# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Glyco_hydro_18 PF00704.28 KXS08763.1 - 2.8e-44 152.1 0.0 3.1e-44 152.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Asp-B-Hydro_N PF05279.11 KXS08766.1 - 5.6 7.0 8.8 6.9 6.7 8.8 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DDE_Tnp_4 PF13359.6 KXS08770.1 - 1.2e-10 41.2 0.0 1.4e-10 41.0 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Transp_cyt_pur PF02133.15 KXS08772.1 - 1.4e-19 70.2 4.0 1.5e-19 70.1 4.0 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin MIR PF02815.19 KXS08774.1 - 2.2e-08 34.2 0.0 8e-08 32.3 0.0 1.8 1 1 0 1 1 1 1 MIR domain MULE PF10551.9 KXS08775.1 - 0.094 13.1 0.1 0.22 11.9 0.0 1.7 2 0 0 2 2 2 0 MULE transposase domain SAM_1 PF00536.30 KXS08775.1 - 0.11 13.0 0.1 0.29 11.6 0.1 1.7 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) TetR_C_35 PF18556.1 KXS08775.1 - 0.13 12.4 0.1 0.23 11.6 0.1 1.3 1 0 0 1 1 1 0 Bacterial Tetracyclin repressor, C-terminal domain TPK_catalytic PF04263.16 KXS08777.1 - 7.6e-33 113.1 0.0 9.2e-33 112.8 0.0 1.1 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain zf-UBP PF02148.19 KXS08778.1 - 9.6e-18 64.3 7.6 1.5e-17 63.7 7.6 1.3 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-UBP_var PF17807.1 KXS08778.1 - 0.054 13.3 2.8 0.14 11.9 2.8 1.7 1 0 0 1 1 1 0 Variant UBP zinc finger zf-C3HC4_3 PF13920.6 KXS08778.1 - 0.19 11.6 6.5 0.11 12.3 2.6 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-HIT PF04438.16 KXS08778.1 - 0.3 11.0 3.6 0.82 9.6 3.6 1.8 1 0 0 1 1 1 0 HIT zinc finger DLEU7 PF15760.5 KXS08779.1 - 0.054 13.0 0.1 0.085 12.3 0.1 1.3 1 0 0 1 1 1 0 Leukemia-associated protein 7 GREB1 PF15782.5 KXS08779.1 - 0.07 10.3 0.3 0.08 10.1 0.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer MFS_1 PF07690.16 KXS08780.1 - 2.8e-23 82.4 28.0 4.1e-23 81.9 28.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily BPL_N PF09825.9 KXS08781.1 - 0.096 11.7 0.1 0.11 11.6 0.1 1.1 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal Sds3 PF08598.11 KXS08783.1 - 3.2e-08 33.9 0.0 3.2e-08 33.9 0.0 2.8 2 1 2 4 4 4 1 Sds3-like Nop53 PF07767.11 KXS08783.1 - 0.35 10.2 35.7 0.045 13.1 29.0 2.1 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) TIC20 PF16166.5 KXS08784.1 - 0.13 12.1 4.3 1.7 8.4 0.1 2.4 2 0 0 2 2 2 0 Chloroplast import apparatus Tic20-like DM PF00751.18 KXS08786.1 - 0.0082 16.0 5.9 0.0082 16.0 5.9 2.1 2 0 0 2 2 2 1 DM DNA binding domain WSK PF03832.13 KXS08787.1 - 0.17 11.6 0.1 0.17 11.6 0.1 2.5 2 0 0 2 2 2 0 WSK motif RVT_1 PF00078.27 KXS08788.1 - 0.026 14.0 0.1 0.053 13.0 0.1 1.5 1 1 1 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) HTH_23 PF13384.6 KXS08790.1 - 1.2e-05 25.0 0.0 2e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KXS08790.1 - 2.7e-05 24.2 0.0 4.5e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_7 PF02796.15 KXS08790.1 - 0.0009 19.3 0.0 0.0097 16.0 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_29 PF13551.6 KXS08790.1 - 0.0022 17.9 0.0 0.0041 17.1 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn helix HTH_Tnp_4 PF13613.6 KXS08790.1 - 0.031 14.0 0.0 0.049 13.4 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease GerE PF00196.19 KXS08790.1 - 0.1 12.1 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family DnaJ PF00226.31 KXS08794.1 - 2.2e-27 94.9 3.5 3.3e-27 94.4 3.5 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_C PF01556.18 KXS08794.1 - 2.1e-16 60.3 0.0 3.1e-16 59.8 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 KXS08794.1 - 3.5e-10 40.1 14.0 6.5e-10 39.2 14.0 1.5 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.19 KXS08794.1 - 0.045 13.8 8.3 0.31 11.1 1.7 2.4 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Anti-TRAP PF15777.5 KXS08794.1 - 3.7 7.6 9.7 0.97 9.5 3.2 2.7 1 1 2 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein BCOR PF15808.5 KXS08795.1 - 0.11 12.8 1.8 0.21 11.8 1.8 1.5 1 0 0 1 1 1 0 BCL-6 co-repressor, non-ankyrin-repeat region Polysacc_synt_2 PF02719.15 KXS08796.1 - 3.4e-58 197.1 0.4 4.6e-58 196.7 0.4 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KXS08796.1 - 2.8e-11 43.1 0.0 2.6e-09 36.6 0.0 2.1 1 1 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 KXS08796.1 - 4.4e-09 36.2 0.1 1.1e-07 31.6 0.1 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXS08796.1 - 3.5e-07 30.0 0.1 3.2e-05 23.5 0.1 2.1 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KXS08796.1 - 0.00036 19.8 0.1 0.13 11.4 0.1 2.4 1 1 1 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.19 KXS08796.1 - 0.028 13.4 1.0 0.12 11.4 0.1 2.3 2 2 1 3 3 3 0 3-beta hydroxysteroid dehydrogenase/isomerase family TFIIF_beta PF02270.15 KXS08796.1 - 0.15 12.2 0.0 0.32 11.2 0.0 1.4 1 0 0 1 1 1 0 TFIIF, beta subunit HTH domain DUF4062 PF13271.6 KXS08797.1 - 0.11 12.8 0.0 0.18 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4062) BUD22 PF09073.10 KXS08798.1 - 4.6 6.5 13.2 5.9 6.1 13.2 1.2 1 0 0 1 1 1 0 BUD22 Sugar_tr PF00083.24 KXS08799.1 - 2.1e-12 46.6 7.5 2.6e-06 26.6 3.8 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KXS08799.1 - 0.001 18.1 11.2 0.017 14.0 3.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3367 PF11847.8 KXS08799.1 - 0.028 12.3 0.3 0.03 12.2 0.3 1.0 1 0 0 1 1 1 0 Alpha-(1->3)-arabinofuranosyltransferase MFS_2 PF13347.6 KXS08799.1 - 0.054 12.0 8.6 0.88 8.0 8.8 1.9 1 1 0 1 1 1 0 MFS/sugar transport protein PMT_2 PF13231.6 KXS08799.1 - 0.075 13.2 5.3 0.68 10.1 0.2 2.1 1 1 1 2 2 2 0 Dolichyl-phosphate-mannose-protein mannosyltransferase TRI12 PF06609.13 KXS08799.1 - 0.085 11.3 3.2 0.35 9.2 1.7 1.9 1 1 1 2 2 2 0 Fungal trichothecene efflux pump (TRI12) Tic110 PF16940.5 KXS08799.1 - 0.2 10.1 0.0 0.27 9.7 0.0 1.2 1 0 0 1 1 1 0 Chloroplast envelope transporter DUF2269 PF10027.9 KXS08799.1 - 5.4 7.1 8.0 46 4.0 7.5 2.0 1 1 1 2 2 2 0 Predicted integral membrane protein (DUF2269) ZapB PF06005.12 KXS08800.1 - 0.016 15.6 0.1 0.026 15.0 0.1 1.3 1 0 0 1 1 1 0 Cell division protein ZapB JAKMIP_CC3 PF16034.5 KXS08800.1 - 0.026 14.5 0.4 0.043 13.8 0.4 1.3 1 0 0 1 1 1 0 JAKMIP CC3 domain zf-CCHC PF00098.23 KXS08802.1 - 0.00055 19.9 1.4 0.00055 19.9 1.4 4.0 4 0 0 4 4 4 2 Zinc knuckle zf-CCHC_3 PF13917.6 KXS08802.1 - 0.0033 17.4 8.4 0.0033 17.4 8.4 2.8 2 1 1 3 3 3 1 Zinc knuckle DUF1299 PF06975.11 KXS08803.1 - 0.061 13.4 0.1 0.15 12.2 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1299) Pox_VLTF3 PF04947.14 KXS08806.1 - 7e-06 25.9 0.0 5.7e-05 22.9 0.0 1.9 1 1 0 1 1 1 1 Poxvirus Late Transcription Factor VLTF3 like ParBc PF02195.18 KXS08808.1 - 0.00037 20.7 0.0 0.00085 19.6 0.0 1.6 1 0 0 1 1 1 1 ParB-like nuclease domain Trypan_PARP PF05887.11 KXS08808.1 - 0.18 11.8 3.6 0.3 11.1 3.6 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF745 PF05335.13 KXS08809.1 - 5.1e-05 23.1 8.7 5.1e-05 23.1 8.7 3.3 3 1 1 4 4 4 1 Protein of unknown function (DUF745) Syntaxin-6_N PF09177.11 KXS08809.1 - 0.041 14.4 0.0 0.041 14.4 0.0 4.8 3 2 1 5 5 5 0 Syntaxin 6, N-terminal Occludin_ELL PF07303.13 KXS08809.1 - 1.3 9.8 17.9 0.31 11.8 1.7 4.9 3 2 1 5 5 5 0 Occludin homology domain FlxA PF14282.6 KXS08809.1 - 2.1 8.4 19.6 0.25 11.4 0.4 4.4 4 1 1 5 5 5 0 FlxA-like protein Spc7 PF08317.11 KXS08809.1 - 7.6 5.3 51.6 0.015 14.2 7.1 4.7 3 2 1 4 4 4 0 Spc7 kinetochore protein FlaC_arch PF05377.11 KXS08809.1 - 9.6 6.7 11.8 90 3.6 0.0 5.4 5 1 1 6 6 6 0 Flagella accessory protein C (FlaC) zf-CCHC PF00098.23 KXS08811.1 - 1.8e-05 24.6 35.7 0.00095 19.1 3.9 5.7 6 0 0 6 6 6 3 Zinc knuckle zf-CCHC_6 PF15288.6 KXS08811.1 - 0.077 12.8 0.9 0.077 12.8 0.9 4.2 2 1 2 4 4 4 0 Zinc knuckle zf-CCHC_4 PF14392.6 KXS08811.1 - 0.091 12.5 0.8 0.091 12.5 0.8 4.1 3 1 1 4 4 4 0 Zinc knuckle DUF2826 PF11442.8 KXS08811.1 - 1.3 8.8 6.8 0.15 11.9 2.6 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2826) zf-C2H2 PF00096.26 KXS08812.1 - 3e-18 65.2 15.4 6.7e-07 29.4 0.5 3.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KXS08812.1 - 6.4e-17 61.1 18.9 1.5e-08 34.7 0.5 3.7 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KXS08812.1 - 1.4e-12 47.3 13.9 7.2e-06 26.4 0.2 3.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KXS08812.1 - 7.5e-09 35.4 12.5 0.00022 21.1 0.3 3.3 3 1 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KXS08812.1 - 1.9e-08 33.9 4.9 0.00019 21.1 0.1 3.2 3 0 0 3 3 3 2 zinc-finger C2H2-type zf-met PF12874.7 KXS08812.1 - 2.4e-06 27.7 7.5 0.013 15.9 0.1 3.4 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KXS08812.1 - 2.3e-05 24.5 9.2 0.0015 18.8 0.1 3.2 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_3rep PF18868.1 KXS08812.1 - 0.00023 21.9 6.0 0.025 15.3 0.3 2.8 2 1 1 3 3 3 2 Zinc finger C2H2-type, 3 repeats zf_UBZ PF18439.1 KXS08812.1 - 0.00046 19.7 5.5 0.14 11.8 0.0 3.3 3 0 0 3 3 3 2 Ubiquitin-Binding Zinc Finger BolA PF01722.18 KXS08812.1 - 0.00087 19.5 0.4 0.035 14.4 0.1 2.6 2 1 1 3 3 3 1 BolA-like protein FYVE PF01363.21 KXS08812.1 - 0.0017 18.5 2.2 0.0048 17.0 2.2 1.9 1 1 0 1 1 1 1 FYVE zinc finger zf-BED PF02892.15 KXS08812.1 - 0.0032 17.4 0.6 0.0032 17.4 0.6 3.1 2 1 1 3 3 3 1 BED zinc finger Prok-RING_1 PF14446.6 KXS08812.1 - 0.0042 17.0 6.9 0.25 11.3 0.2 3.0 3 0 0 3 3 3 2 Prokaryotic RING finger family 1 Zn-ribbon_8 PF09723.10 KXS08812.1 - 0.022 14.9 8.0 0.49 10.6 2.5 3.0 2 1 0 2 2 2 0 Zinc ribbon domain zf-C2HC_2 PF13913.6 KXS08812.1 - 0.043 13.7 8.3 0.89 9.5 0.2 3.4 3 0 0 3 3 3 0 zinc-finger of a C2HC-type Zn-C2H2_12 PF18112.1 KXS08812.1 - 0.054 14.0 3.4 17 6.0 0.0 3.5 3 1 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain Zn_ribbon_SprT PF17283.2 KXS08812.1 - 0.058 13.3 0.4 0.058 13.3 0.4 2.5 1 1 2 3 3 3 0 SprT-like zinc ribbon domain zf-MYST PF17772.1 KXS08812.1 - 0.074 12.7 3.8 1.9 8.1 0.1 2.6 2 1 1 3 3 3 0 MYST family zinc finger domain Zn_Tnp_IS1595 PF12760.7 KXS08812.1 - 0.074 13.0 6.0 0.43 10.6 1.9 2.3 2 0 0 2 2 2 0 Transposase zinc-ribbon domain DUF2256 PF10013.9 KXS08812.1 - 0.086 13.0 3.2 6.4 7.0 0.0 3.1 3 1 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) DZR PF12773.7 KXS08812.1 - 0.087 12.9 5.1 0.09 12.8 0.7 2.1 1 1 1 2 2 2 0 Double zinc ribbon zf-HIT PF04438.16 KXS08812.1 - 0.11 12.4 10.8 0.94 9.4 0.3 3.2 3 1 0 3 3 3 0 HIT zinc finger zf-Di19 PF05605.12 KXS08812.1 - 0.11 12.7 5.3 4.9 7.5 0.8 2.5 1 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding MCM_OB PF17207.3 KXS08812.1 - 0.21 11.4 1.8 0.31 10.9 1.8 1.5 1 1 0 1 1 1 0 MCM OB domain Zf_RING PF16744.5 KXS08812.1 - 0.23 11.6 5.9 0.54 10.4 2.2 2.6 1 1 1 2 2 2 0 KIAA1045 RING finger zf-Sec23_Sec24 PF04810.15 KXS08812.1 - 0.36 10.9 3.4 4.9 7.3 0.1 2.8 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger XPA_N PF01286.18 KXS08812.1 - 0.45 10.6 7.3 8.3 6.6 0.1 3.1 3 0 0 3 3 3 0 XPA protein N-terminal zf-FCS PF06467.14 KXS08812.1 - 0.82 9.7 8.4 10 6.1 0.2 3.0 2 1 1 3 3 3 0 MYM-type Zinc finger with FCS sequence motif Cript PF10235.9 KXS08812.1 - 1.4 9.6 6.3 12 6.6 0.2 2.7 1 1 1 2 2 2 0 Microtubule-associated protein CRIPT zf_ZIC PF18366.1 KXS08812.1 - 1.4 9.1 5.7 15 5.8 0.4 2.9 1 1 2 3 3 3 0 Zic proteins zinc finger domain zf-AN1 PF01428.16 KXS08812.1 - 2.7 8.2 12.6 5.7 7.2 0.2 3.3 3 0 0 3 3 3 0 AN1-like Zinc finger ADK_lid PF05191.14 KXS08812.1 - 2.8 8.0 11.5 3.6 7.6 5.6 2.9 2 1 0 2 2 2 0 Adenylate kinase, active site lid zf-H2C2_5 PF13909.6 KXS08812.1 - 4.1 7.2 0.0 4.1 7.2 0.0 4.7 5 0 0 5 5 5 0 C2H2-type zinc-finger domain TFIIS_C PF01096.18 KXS08812.1 - 6 6.8 9.3 23 4.9 0.4 3.1 3 0 0 3 3 3 0 Transcription factor S-II (TFIIS) C1_2 PF03107.16 KXS08812.1 - 7.8 6.9 18.7 4.6 7.6 4.3 3.8 1 1 2 3 3 3 0 C1 domain zf-H2C2_2 PF13465.6 KXS08813.1 - 3e-13 49.5 21.2 3.7e-07 30.3 0.6 3.9 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.26 KXS08813.1 - 1.3e-12 47.4 22.5 6e-05 23.3 2.1 3.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXS08813.1 - 4.1e-09 36.5 20.1 0.00076 20.1 1.5 3.2 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KXS08813.1 - 1.4e-05 25.3 3.6 2.2e-05 24.6 3.6 1.3 1 1 0 1 1 1 1 C2H2-type zinc ribbon zf-H2C2_5 PF13909.6 KXS08813.1 - 6e-05 22.7 12.8 0.0044 16.7 2.0 3.2 3 1 0 3 3 3 2 C2H2-type zinc-finger domain zf-C2H2_11 PF16622.5 KXS08813.1 - 0.042 13.6 3.3 0.064 13.0 0.4 2.5 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_aberr PF17017.5 KXS08813.1 - 0.11 12.7 3.4 0.44 10.7 3.1 2.0 1 1 0 1 1 1 0 Aberrant zinc-finger zf-met PF12874.7 KXS08813.1 - 0.28 11.6 7.8 6.7 7.2 0.0 3.7 3 1 0 3 3 3 0 Zinc-finger of C2H2 type TrkA_C PF02080.21 KXS08814.1 - 0.045 13.6 0.0 0.12 12.2 0.0 1.8 1 0 0 1 1 1 0 TrkA-C domain Herpes_ori_bp PF02399.15 KXS08815.1 - 3.3e-24 85.0 2.4 4.2e-23 81.4 2.4 2.1 1 1 0 1 1 1 1 Origin of replication binding protein DEAD PF00270.29 KXS08815.1 - 0.00074 19.3 0.0 0.0047 16.7 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase PriCT_2 PF08707.11 KXS08815.1 - 0.01 16.2 0.2 0.031 14.6 0.2 1.8 1 0 0 1 1 1 0 Primase C terminal 2 (PriCT-2) DUF5321 PF17254.2 KXS08815.1 - 0.05 13.0 0.1 0.14 11.6 0.1 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5321) Thioredoxin PF00085.20 KXS08815.1 - 0.13 12.3 0.1 0.4 10.7 0.1 1.8 1 0 0 1 1 1 0 Thioredoxin zf-CCHC PF00098.23 KXS08817.1 - 5.7e-10 38.8 9.1 8.7e-05 22.4 3.5 2.3 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_3 PF13917.6 KXS08817.1 - 0.0081 16.1 7.0 0.015 15.3 1.1 2.3 1 1 1 2 2 2 1 Zinc knuckle TMEM238 PF15125.6 KXS08817.1 - 0.043 14.0 2.3 0.084 13.1 2.3 1.4 1 0 0 1 1 1 0 TMEM238 protein family DUF3040 PF11239.8 KXS08817.1 - 0.11 12.8 3.4 0.31 11.3 3.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) eIF3g PF12353.8 KXS08817.1 - 0.45 10.9 0.1 0.45 10.9 0.1 1.5 1 1 1 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G zf-CCHC_2 PF13696.6 KXS08817.1 - 0.45 10.4 13.5 1.3 8.9 1.2 2.3 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.6 KXS08817.1 - 1.1 9.1 4.5 12 5.7 1.9 2.3 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC PF00098.23 KXS08818.1 - 1.6e-09 37.4 10.8 0.00017 21.5 3.5 2.3 2 0 0 2 2 2 2 Zinc knuckle Retrotran_gag_2 PF14223.6 KXS08818.1 - 8.8e-05 22.2 0.0 0.00011 21.9 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC_2 PF13696.6 KXS08818.1 - 0.1 12.4 15.5 0.15 11.9 2.6 2.6 2 0 0 2 2 2 0 Zinc knuckle TMEM238 PF15125.6 KXS08818.1 - 0.5 10.6 4.4 1.1 9.5 4.4 1.5 1 0 0 1 1 1 0 TMEM238 protein family zf-CCHC_3 PF13917.6 KXS08818.1 - 0.68 9.9 6.9 1.6 8.8 1.2 2.6 2 1 1 3 3 3 0 Zinc knuckle N6_N4_Mtase PF01555.18 KXS08819.1 - 0.0019 18.0 0.0 0.0075 16.0 0.0 2.0 1 1 0 1 1 1 1 DNA methylase ParBc PF02195.18 KXS08819.1 - 0.084 13.2 0.0 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 ParB-like nuclease domain Cwf_Cwc_15 PF04889.12 KXS08819.1 - 0.87 9.3 8.5 1.7 8.3 8.5 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DNA_pol_phi PF04931.13 KXS08819.1 - 0.95 7.5 7.0 1.4 6.9 7.0 1.2 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 KXS08819.1 - 3.7 5.6 7.0 5.7 5.0 7.0 1.2 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.12 KXS08819.1 - 4.4 6.5 10.2 8.1 5.7 10.2 1.4 1 0 0 1 1 1 0 NOA36 protein Extensin_2 PF04554.13 KXS08823.1 - 7 6.8 22.4 8.3 6.6 16.2 3.1 1 1 1 2 2 2 0 Extensin-like region Lectin_N PF03954.14 KXS08824.1 - 0.069 12.9 0.1 0.17 11.6 0.1 1.6 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain C2-C2_1 PF11618.8 KXS08828.1 - 7.8e-17 61.7 0.1 1.6e-16 60.7 0.1 1.5 1 0 0 1 1 1 1 First C2 domain of RPGR-interacting protein 1 Imm6 PF14434.6 KXS08828.1 - 0.069 13.1 1.6 0.098 12.6 0.1 1.9 2 0 0 2 2 2 0 Immunity protein Imm6 Sec15 PF04091.12 KXS08828.1 - 0.32 10.4 5.2 7.1 5.9 0.1 3.0 3 0 0 3 3 3 0 Exocyst complex subunit Sec15-like XkdW PF09636.10 KXS08828.1 - 0.35 11.0 7.8 0.34 11.0 0.2 2.4 2 0 0 2 2 2 0 XkdW protein V_ATPase_I PF01496.19 KXS08828.1 - 1.9 6.3 6.1 0.44 8.4 2.1 1.7 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family GAS PF13851.6 KXS08828.1 - 4.5 6.6 20.9 1.9 7.8 12.5 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding CCDC24 PF15669.5 KXS08829.1 - 0.014 15.3 0.6 0.022 14.7 0.6 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family SNF2_N PF00176.23 KXS08830.1 - 1.1e-51 175.6 0.0 3e-51 174.2 0.0 1.7 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-C3HC4_2 PF13923.6 KXS08830.1 - 1.3e-08 34.5 7.6 3.1e-08 33.3 7.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXS08830.1 - 9.5e-08 32.3 8.5 3.1e-07 30.6 8.5 2.0 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KXS08830.1 - 4.5e-07 29.6 7.6 9.6e-07 28.6 7.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Helicase_C PF00271.31 KXS08830.1 - 1.9e-06 28.1 0.0 3.7e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.6 KXS08830.1 - 7.3e-06 25.7 6.2 1.6e-05 24.7 6.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXS08830.1 - 4e-05 23.5 7.2 0.0001 22.2 7.2 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KXS08830.1 - 0.00015 21.7 5.3 0.00052 20.0 5.3 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 KXS08830.1 - 0.0012 19.1 11.2 0.0064 16.8 11.2 2.2 1 1 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 KXS08830.1 - 0.0052 16.6 5.4 0.014 15.3 5.4 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 TPR_8 PF13181.6 KXS08830.1 - 0.066 13.5 0.0 0.6 10.5 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-C3HC4_4 PF15227.6 KXS08830.1 - 0.076 13.2 8.4 0.2 11.9 8.4 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING TPR_7 PF13176.6 KXS08830.1 - 0.077 13.1 0.0 2.3 8.4 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-RING_10 PF16685.5 KXS08830.1 - 0.44 10.7 7.8 0.1 12.7 3.9 2.0 2 0 0 2 2 2 0 zinc RING finger of MSL2 Pyridoxal_deC PF00282.19 KXS08831.1 - 3.8e-15 55.5 0.0 5.6e-15 54.9 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 KXS08831.1 - 1.2e-09 37.6 0.0 2.7e-09 36.5 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KXS08831.1 - 8.4e-05 22.0 0.0 0.00012 21.5 0.0 1.1 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 KXS08831.1 - 0.00063 19.0 0.0 0.00093 18.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KXS08831.1 - 0.14 10.7 0.0 0.17 10.4 0.0 1.1 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Peptidase_S9 PF00326.21 KXS08832.1 - 0.029 13.8 0.1 2.1 7.8 0.0 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KXS08832.1 - 0.036 13.3 0.0 2.9 7.1 0.0 2.1 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Acetyltransf_7 PF13508.7 KXS08833.1 - 2.9e-07 30.8 0.0 4.1e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXS08833.1 - 3.7e-07 30.4 0.0 4.7e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXS08833.1 - 8.9e-05 22.4 0.0 0.00013 21.9 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KXS08833.1 - 0.12 12.5 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase adh_short_C2 PF13561.6 KXS08834.1 - 2.2e-58 197.6 0.3 2.6e-58 197.4 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXS08834.1 - 2.3e-47 161.0 0.6 3e-47 160.6 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXS08834.1 - 2e-10 40.9 0.4 3.7e-10 40.0 0.4 1.4 1 0 0 1 1 1 1 KR domain ASC PF00858.24 KXS08836.1 - 4.5e-24 85.2 16.1 5.1e-15 55.4 7.6 2.3 1 1 1 2 2 2 2 Amiloride-sensitive sodium channel MFS_1 PF07690.16 KXS08836.1 - 5.9e-06 25.4 2.3 5.9e-06 25.4 2.3 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXS08836.1 - 0.00012 21.1 0.9 0.00017 20.6 0.9 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter TIG PF01833.24 KXS08836.1 - 0.0053 16.8 2.2 0.012 15.7 0.1 2.7 3 1 0 3 3 3 1 IPT/TIG domain RPM2 PF08579.11 KXS08836.1 - 0.17 12.3 0.1 0.29 11.5 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial ribonuclease P subunit (RPM2) ParBc PF02195.18 KXS08838.1 - 0.0027 18.0 0.0 0.0057 16.9 0.0 1.6 1 0 0 1 1 1 1 ParB-like nuclease domain DUF3990 PF13151.6 KXS08841.1 - 9.3e-08 31.9 0.0 2e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3990) HHH_3 PF12836.7 KXS08841.1 - 0.00012 22.2 0.0 0.0015 18.7 0.0 2.4 1 1 0 1 1 1 1 Helix-hairpin-helix motif HHH_6 PF14579.6 KXS08841.1 - 0.00072 19.8 0.0 0.0018 18.5 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif BSP PF04450.12 KXS08842.1 - 2.7e-06 27.4 0.4 4.8e-06 26.5 0.4 1.4 1 0 0 1 1 1 1 Peptidase of plants and bacteria LRR_6 PF13516.6 KXS08843.1 - 6.2e-56 181.8 36.6 8.9e-08 31.6 0.4 9.4 9 0 0 9 9 9 8 Leucine Rich repeat LRR_1 PF00560.33 KXS08843.1 - 5.9e-11 41.3 0.0 4.9 8.1 0.0 7.7 8 0 0 8 8 8 1 Leucine Rich Repeat LRR_4 PF12799.7 KXS08843.1 - 2.1e-08 34.3 32.2 0.0023 18.3 0.7 5.7 1 1 8 9 9 9 8 Leucine Rich repeats (2 copies) Caskin1-CID PF16600.5 KXS08843.1 - 4e-05 24.1 10.1 2.6 8.7 0.0 7.0 8 1 0 8 8 8 1 Caskin1 CASK-interaction domain DUF3175 PF11373.8 KXS08843.1 - 0.0091 16.1 2.7 14 5.9 0.1 4.2 2 1 2 4 4 4 1 Protein of unknown function (DUF3175) DUF3107 PF11305.8 KXS08843.1 - 0.012 15.8 8.4 1.9 8.8 0.0 5.3 2 1 5 7 7 7 0 Protein of unknown function (DUF3107) FlgT_M PF16539.5 KXS08843.1 - 0.035 14.2 7.8 2.7 8.1 0.4 4.1 1 1 3 4 4 4 0 Flagellar assembly protein T, middle domain Spc24 PF08286.11 KXS08843.1 - 0.13 12.6 8.0 0.89 9.8 0.2 3.3 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 LRR_8 PF13855.6 KXS08843.1 - 0.2 11.4 41.6 0.48 10.2 2.8 7.6 2 1 5 7 7 7 0 Leucine rich repeat Ntox10 PF15520.6 KXS08843.1 - 0.8 9.5 4.9 12 5.7 0.1 3.0 1 1 2 3 3 3 0 Novel toxin 10 Sel1 PF08238.12 KXS08844.1 - 1.6e-23 82.6 19.8 1.3e-07 32.0 0.4 6.6 7 0 0 7 7 7 5 Sel1 repeat Pkinase_Tyr PF07714.17 KXS08844.1 - 4.8e-05 22.8 0.0 6.8e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase TPR_16 PF13432.6 KXS08844.1 - 0.0022 18.6 5.3 0.13 13.0 0.8 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat Pkinase PF00069.25 KXS08845.1 - 1.5e-22 80.2 0.0 6.2e-18 65.1 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXS08845.1 - 3.5e-18 65.8 0.0 1.2e-13 50.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 KXS08845.1 - 0.00011 21.3 0.0 0.074 12.0 0.0 2.1 2 0 0 2 2 2 2 Haspin like kinase domain APH PF01636.23 KXS08845.1 - 0.0021 18.0 0.0 0.0033 17.4 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KXS08845.1 - 0.052 13.1 0.0 0.081 12.5 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Choline_kinase PF01633.20 KXS08845.1 - 0.059 12.9 0.0 0.09 12.4 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 KXS08845.1 - 0.12 11.2 0.0 0.15 10.8 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase F-box-like PF12937.7 KXS08848.1 - 1.9e-05 24.4 0.1 5.1e-05 23.1 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXS08848.1 - 0.011 15.6 0.1 0.028 14.3 0.1 1.6 1 0 0 1 1 1 0 F-box domain Spc7 PF08317.11 KXS08852.1 - 0.0022 16.9 8.1 0.0022 16.9 8.1 5.1 1 1 4 6 6 6 3 Spc7 kinetochore protein Gp58 PF07902.11 KXS08852.1 - 0.0026 16.2 2.6 0.0026 16.2 2.6 2.8 2 1 0 2 2 2 1 gp58-like protein Fez1 PF06818.15 KXS08852.1 - 0.0034 17.9 18.4 0.0034 17.9 18.4 5.3 1 1 4 5 5 5 1 Fez1 CENP-F_leu_zip PF10473.9 KXS08852.1 - 0.0045 17.0 5.3 0.0045 17.0 5.3 7.1 3 3 4 7 7 4 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Nsp1_C PF05064.13 KXS08852.1 - 0.0089 15.8 0.2 0.0089 15.8 0.2 3.2 3 2 0 3 3 2 1 Nsp1-like C-terminal region DUF1664 PF07889.12 KXS08852.1 - 0.068 13.2 25.5 0.13 12.3 0.7 6.2 4 2 1 6 6 6 0 Protein of unknown function (DUF1664) TMPIT PF07851.13 KXS08852.1 - 0.071 12.3 0.2 0.071 12.3 0.2 4.2 3 1 1 5 5 5 0 TMPIT-like protein SlyX PF04102.12 KXS08852.1 - 0.073 13.7 0.7 0.073 13.7 0.7 8.6 6 3 3 9 9 8 0 SlyX Fib_alpha PF08702.10 KXS08852.1 - 0.1 12.7 15.7 0.42 10.8 0.1 4.9 3 1 2 5 5 5 0 Fibrinogen alpha/beta chain family Baculo_PEP_C PF04513.12 KXS08852.1 - 0.12 12.4 5.0 2.8 8.0 0.0 4.5 4 2 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Cor1 PF04803.12 KXS08852.1 - 0.46 10.7 12.6 0.88 9.8 1.5 3.7 3 1 0 3 3 3 0 Cor1/Xlr/Xmr conserved region DUF641 PF04859.12 KXS08852.1 - 0.53 10.6 50.6 0.12 12.7 2.6 7.7 3 1 5 8 8 8 0 Plant protein of unknown function (DUF641) Prominin PF05478.11 KXS08852.1 - 0.76 7.7 6.0 0.31 9.0 0.2 2.7 1 1 1 3 3 3 0 Prominin BLOC1_2 PF10046.9 KXS08852.1 - 0.89 9.9 15.9 2.7 8.4 0.2 5.0 4 2 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF725 PF05267.12 KXS08852.1 - 1.5 8.8 5.4 0.69 9.9 1.2 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF725) ATG16 PF08614.11 KXS08852.1 - 6.3 7.0 99.7 0.22 11.7 14.8 7.3 1 1 6 7 7 6 0 Autophagy protein 16 (ATG16) Lectin_N PF03954.14 KXS08852.1 - 7.9 6.2 14.0 0.2 11.4 0.2 4.6 5 2 1 6 6 6 0 Hepatic lectin, N-terminal domain ParBc PF02195.18 KXS08853.1 - 0.12 12.7 0.0 0.16 12.3 0.0 1.2 1 0 0 1 1 1 0 ParB-like nuclease domain NeA_P2 PF12312.8 KXS08854.1 - 0.088 12.3 0.0 0.12 11.8 0.0 1.1 1 0 0 1 1 1 0 Nepovirus subgroup A polyprotein DUF3500 PF12006.8 KXS08854.1 - 0.11 12.0 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3500) Ole-e-6 PF09253.10 KXS08857.1 - 0.066 13.2 0.8 0.14 12.1 0.8 1.5 1 0 0 1 1 1 0 Pollen allergen ole e 6 DUF5595 PF18077.1 KXS08858.1 - 0.4 10.8 5.6 0.92 9.6 5.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5595) DivIC PF04977.15 KXS08858.1 - 1.2 8.9 9.3 0.24 11.2 5.2 1.9 2 1 0 2 2 2 0 Septum formation initiator F-box-like PF12937.7 KXS08859.1 - 3.1e-08 33.4 0.0 6.4e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXS08859.1 - 4.2e-05 23.3 0.0 8.1e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 F-box domain PRANC PF09372.10 KXS08859.1 - 0.21 11.9 0.2 0.64 10.4 0.0 1.8 2 0 0 2 2 2 0 PRANC domain Peptidase_M20 PF01546.28 KXS08862.1 - 2.5e-32 112.2 0.0 9.4e-32 110.4 0.0 1.8 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KXS08862.1 - 1.1e-10 41.4 0.0 3.5e-10 39.8 0.0 1.8 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KXS08862.1 - 1.3e-07 31.5 0.0 2.7e-05 23.9 0.0 2.1 2 0 0 2 2 2 2 Peptidase family M28 Glyco_hydro_7 PF00840.20 KXS08863.1 - 7.7e-25 87.5 20.1 9.6e-19 67.4 1.5 4.4 1 1 2 3 3 3 2 Glycosyl hydrolase family 7 Orthoreo_P10 PF07204.11 KXS08864.1 - 0.03 14.3 1.5 5.5 7.0 0.2 2.4 2 1 0 2 2 2 0 Orthoreovirus membrane fusion protein p10 Vfa1 PF08432.10 KXS08865.1 - 1.5 9.1 7.2 1.9 8.8 7.2 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF913 PF06025.12 KXS08865.1 - 4.4 6.2 4.2 4.4 6.2 4.2 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) VWA PF00092.28 KXS08866.1 - 6.7e-15 55.8 0.8 1.1e-14 55.1 0.8 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KXS08866.1 - 7.2e-12 45.9 0.1 1.4e-11 45.0 0.1 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 KXS08866.1 - 0.011 15.1 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein BclA_C PF18573.1 KXS08866.1 - 0.06 13.3 3.1 1.2 9.0 0.0 2.9 3 1 0 3 3 3 0 BclA C-terminal domain Sel1 PF08238.12 KXS08868.1 - 3.7e-25 87.8 23.9 8.5e-09 35.8 0.1 6.8 6 1 0 6 6 6 4 Sel1 repeat TPR_19 PF14559.6 KXS08868.1 - 1e-08 35.6 0.2 0.0079 16.7 0.1 2.7 3 1 0 3 3 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 KXS08868.1 - 4.2e-07 29.6 12.7 0.00018 21.4 0.0 5.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 KXS08868.1 - 4.9e-07 30.3 1.5 0.0027 18.3 0.0 4.0 2 2 3 5 5 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 KXS08868.1 - 3.8e-06 26.7 5.3 0.015 15.5 0.0 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 KXS08868.1 - 8.8e-06 25.9 1.8 0.006 16.8 0.0 4.2 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 KXS08868.1 - 1.2e-05 24.9 12.6 0.00064 19.4 0.0 5.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 KXS08868.1 - 8e-05 23.1 0.1 4.4 8.4 0.0 4.1 3 2 1 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 KXS08868.1 - 0.00016 21.4 0.4 2.7 8.2 0.0 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat MIT PF04212.18 KXS08868.1 - 0.00041 20.4 0.4 2.7 8.1 0.0 3.9 3 1 1 4 4 4 1 MIT (microtubule interacting and transport) domain TPR_6 PF13174.6 KXS08868.1 - 0.00054 20.4 2.7 4 8.3 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KXS08868.1 - 0.0014 18.8 1.1 0.068 13.4 0.2 2.7 1 1 2 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 KXS08868.1 - 0.0015 18.3 1.1 1.1 9.2 0.0 4.1 4 1 0 4 4 4 1 Tetratricopeptide repeat ANTAR PF03861.14 KXS08868.1 - 0.0088 15.9 0.0 0.66 9.9 0.0 2.3 2 0 0 2 2 2 1 ANTAR domain DUF5112 PF17139.4 KXS08868.1 - 0.011 15.2 0.5 0.41 10.1 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5112) PPR PF01535.20 KXS08868.1 - 0.015 15.5 0.8 3 8.3 0.1 3.2 4 0 0 4 4 3 0 PPR repeat TPR_21 PF09976.9 KXS08868.1 - 0.024 14.4 0.5 0.057 13.1 0.1 1.7 2 0 0 2 2 2 0 Tetratricopeptide repeat-like domain TPR_MalT PF17874.1 KXS08868.1 - 0.026 13.9 0.0 0.046 13.1 0.0 1.4 1 1 0 1 1 1 0 MalT-like TPR region DUF2225 PF09986.9 KXS08868.1 - 0.11 12.2 0.1 0.42 10.3 0.0 1.9 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) TFIIB PF00382.19 KXS08868.1 - 0.23 11.5 0.3 22 5.2 0.0 2.9 3 0 0 3 3 3 0 Transcription factor TFIIB repeat TPR_11 PF13414.6 KXS08868.1 - 0.36 10.5 9.2 23 4.8 0.2 5.1 4 3 0 4 4 4 0 TPR repeat TAP_C PF03943.13 KXS08868.1 - 0.38 10.4 0.1 0.38 10.4 0.1 2.2 3 0 0 3 3 2 0 TAP C-terminal domain LRR_6 PF13516.6 KXS08869.1 - 5.4e-55 178.8 34.7 1.9e-06 27.5 0.3 12.3 12 0 0 12 12 12 11 Leucine Rich repeat Arm-DNA-bind_1 PF09003.10 KXS08869.1 - 8.4e-13 48.3 35.5 1.3 9.2 0.1 11.5 2 1 10 12 12 12 5 Bacteriophage lambda integrase, Arm DNA-binding domain HOASN PF14515.6 KXS08869.1 - 2.7e-11 43.7 33.0 1.1 9.7 0.1 10.5 1 1 10 11 11 11 4 Haem-oxygenase-associated N-terminal helices LRR_1 PF00560.33 KXS08869.1 - 6.2e-07 29.1 0.0 1.2e+02 3.9 0.0 8.4 10 0 0 10 10 9 0 Leucine Rich Repeat LRR_8 PF13855.6 KXS08869.1 - 1.4e-05 24.7 20.4 0.5 10.2 0.5 7.9 1 1 8 9 9 9 1 Leucine rich repeat LRR_4 PF12799.7 KXS08869.1 - 2.4e-05 24.6 22.3 0.72 10.4 0.4 6.6 2 2 5 7 7 7 5 Leucine Rich repeats (2 copies) YwqJ-deaminase PF14431.6 KXS08869.1 - 0.00011 22.4 1.5 15 5.7 0.0 5.1 1 1 6 7 7 7 0 YwqJ-like deaminase DUF2202 PF09968.9 KXS08869.1 - 0.00023 21.0 11.0 2.9 7.7 0.1 7.3 1 1 7 8 8 8 1 Uncharacterized protein domain (DUF2202) DUF2682 PF10909.8 KXS08869.1 - 0.00028 21.3 9.0 20 5.8 0.0 5.9 1 1 1 5 5 5 0 Protein of unknown function (DUF2682) DUF3701 PF12482.8 KXS08869.1 - 0.00071 19.6 6.0 15 5.7 0.0 7.1 1 1 8 9 9 9 0 Phage integrase protein Mg_chelatase_C PF13335.6 KXS08869.1 - 0.0022 18.6 26.8 23 5.7 0.2 7.8 1 1 5 7 7 7 0 Magnesium chelatase, subunit ChlI C-terminal SpoU_sub_bind PF08032.12 KXS08869.1 - 0.0083 16.4 6.2 94 3.4 0.0 6.2 5 1 4 9 9 8 0 RNA 2'-O ribose methyltransferase substrate binding YusW PF14039.6 KXS08869.1 - 0.029 14.9 3.2 53 4.4 0.1 4.3 1 1 4 6 6 6 0 YusW-like protein AhpC-TSA PF00578.21 KXS08869.1 - 0.035 14.0 0.0 13 5.8 0.0 4.4 1 1 1 4 4 4 0 AhpC/TSA family DNase-RNase PF02577.14 KXS08869.1 - 0.17 11.5 3.5 4 7.1 0.0 3.7 3 2 0 3 3 3 0 Bifunctional nuclease MRP-S35 PF10246.9 KXS08869.1 - 0.62 10.1 4.5 40 4.2 0.1 4.3 2 2 1 5 5 5 0 Mitochondrial ribosomal protein MRP-S35 Gallidermin PF02052.15 KXS08869.1 - 9.4 6.7 10.6 50 4.3 0.0 5.5 7 2 1 8 8 8 0 Gallidermin GAT PF03127.14 KXS08869.1 - 10 6.5 16.4 4.1 7.8 0.1 6.6 2 2 7 9 9 9 0 GAT domain LRR_6 PF13516.6 KXS08870.1 - 1.6e-40 133.7 49.3 2.1e-05 24.2 0.6 11.8 12 0 0 12 12 12 9 Leucine Rich repeat LRR_1 PF00560.33 KXS08870.1 - 1.4e-07 31.0 1.8 12 6.9 0.0 6.5 6 0 0 6 6 6 2 Leucine Rich Repeat LRR_4 PF12799.7 KXS08870.1 - 1.5e-07 31.6 18.1 0.015 15.7 1.0 5.5 3 1 3 6 6 6 6 Leucine Rich repeats (2 copies) Beta_helix PF13229.6 KXS08870.1 - 0.032 14.1 2.7 0.35 10.7 2.2 2.4 1 1 1 2 2 2 0 Right handed beta helix region SpoU_sub_bind PF08032.12 KXS08870.1 - 0.1 12.9 3.2 26 5.2 0.0 4.5 4 1 1 6 6 6 0 RNA 2'-O ribose methyltransferase substrate binding LRR_8 PF13855.6 KXS08870.1 - 0.42 10.4 23.5 11 5.9 2.0 6.8 4 3 0 4 4 4 0 Leucine rich repeat ActA PF05058.12 KXS08872.1 - 0.017 13.5 0.1 0.022 13.2 0.1 1.1 1 0 0 1 1 1 0 ActA Protein Corona_nucleoca PF00937.18 KXS08872.1 - 0.9 8.5 7.6 1.3 8.0 7.6 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein DUF4799 PF16056.5 KXS08872.1 - 1.1 8.4 9.9 0.063 12.4 0.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4799) RNR_Alpha PF17975.1 KXS08873.1 - 4.5e-37 126.6 0.8 1.1e-36 125.4 0.1 2.0 2 0 0 2 2 2 1 Ribonucleotide reductase alpha domain Ribonuc_red_lgC PF02867.15 KXS08873.1 - 7.1e-13 47.9 0.2 1.8e-05 23.5 0.1 3.3 3 0 0 3 3 3 3 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 KXS08873.1 - 0.057 13.4 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 Ribonucleotide reductase, all-alpha domain zf-CCHC PF00098.23 KXS08874.1 - 0.016 15.3 2.7 0.036 14.2 2.7 1.6 1 0 0 1 1 1 0 Zinc knuckle AAA_12 PF13087.6 KXS08875.1 - 1.5e-14 54.1 0.3 5.2e-14 52.3 0.3 2.0 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KXS08875.1 - 1.8e-14 54.2 0.0 4e-06 26.8 0.0 3.4 3 1 0 3 3 3 2 AAA domain AAA_30 PF13604.6 KXS08875.1 - 9.6e-13 48.3 0.0 3.6e-12 46.4 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KXS08875.1 - 1.9e-11 44.5 0.0 2.5e-10 40.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain Helicase_C PF00271.31 KXS08875.1 - 2.9e-10 40.5 0.0 1.2e-09 38.5 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXS08875.1 - 3e-09 37.1 0.0 0.0033 17.4 0.1 3.5 2 1 1 3 3 3 2 Type III restriction enzyme, res subunit TTC5_OB PF16669.5 KXS08875.1 - 1.2e-05 25.0 5.3 0.17 11.6 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat protein 5 OB fold domain DEAD PF00270.29 KXS08875.1 - 0.00016 21.5 0.0 0.0053 16.5 0.0 2.9 3 0 0 3 3 3 1 DEAD/DEAH box helicase T2SSE PF00437.20 KXS08875.1 - 0.00044 19.4 0.0 3.2 6.7 0.0 3.3 3 0 0 3 3 3 1 Type II/IV secretion system protein PhoH PF02562.16 KXS08875.1 - 0.0018 17.7 0.0 0.012 15.1 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein UvrD-helicase PF00580.21 KXS08875.1 - 0.011 15.2 0.2 0.074 12.6 0.0 2.6 4 0 0 4 4 4 0 UvrD/REP helicase N-terminal domain SWI2_SNF2 PF18766.1 KXS08875.1 - 0.015 15.0 2.5 1.6 8.3 0.1 3.1 3 0 0 3 3 3 0 SWI2/SNF2 ATPase Whib PF02467.16 KXS08875.1 - 0.035 14.7 0.2 0.15 12.6 0.1 2.1 2 0 0 2 2 2 0 Transcription factor WhiB Helicase_RecD PF05127.14 KXS08875.1 - 0.037 13.9 0.0 0.1 12.5 0.0 1.8 1 0 0 1 1 1 0 Helicase AAA_22 PF13401.6 KXS08875.1 - 0.039 14.2 0.0 1.4 9.1 0.0 3.0 2 0 0 2 2 2 0 AAA domain SNF2_N PF00176.23 KXS08875.1 - 0.049 12.3 0.1 0.27 9.9 0.1 1.9 1 1 1 2 2 2 0 SNF2 family N-terminal domain AAA_25 PF13481.6 KXS08875.1 - 0.077 12.6 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KXS08875.1 - 0.11 12.9 0.0 3.1 8.2 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Glyco_transf_41 PF13844.6 KXS08877.1 - 2.5e-22 79.0 3.8 1.8e-14 53.1 0.0 3.0 2 1 1 3 3 3 2 Glycosyl transferase family 41 HHV-5_US34A PF17087.5 KXS08877.1 - 0.67 10.1 5.3 18 5.6 0.2 3.3 3 0 0 3 3 3 0 Herpesvirus US34A protein family DUF1664 PF07889.12 KXS08877.1 - 4.9 7.2 18.5 0.08 13.0 0.8 3.8 2 1 0 4 4 4 0 Protein of unknown function (DUF1664) HMMR_N PF15905.5 KXS08877.1 - 5.9 6.3 52.0 0.82 9.1 24.1 2.9 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal RVT_1 PF00078.27 KXS08880.1 - 0.019 14.5 0.0 0.033 13.7 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) adh_short PF00106.25 KXS08881.1 - 1.3e-47 161.8 0.0 1.7e-47 161.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXS08881.1 - 6.9e-41 140.3 0.0 8.3e-41 140.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXS08881.1 - 2.9e-11 43.6 0.0 5.5e-11 42.7 0.0 1.4 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KXS08881.1 - 0.00044 19.8 0.0 0.00092 18.7 0.0 1.7 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KXS08881.1 - 0.11 11.6 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF4763 PF15960.5 KXS08882.1 - 0.01 15.2 11.1 0.019 14.3 11.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) BRE1 PF08647.11 KXS08882.1 - 0.012 15.7 8.1 0.027 14.5 8.1 1.6 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase DUF812 PF05667.11 KXS08882.1 - 0.052 12.4 14.1 0.079 11.8 14.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) MPS2 PF17060.5 KXS08882.1 - 0.059 12.6 8.2 0.086 12.1 8.2 1.2 1 0 0 1 1 1 0 Monopolar spindle protein 2 Bcr-Abl_Oligo PF09036.10 KXS08882.1 - 0.15 12.1 4.0 14 5.7 1.3 2.9 2 1 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain Spc29 PF17082.5 KXS08882.1 - 0.18 11.6 6.8 1.8 8.4 0.6 2.4 1 1 1 2 2 2 0 Spindle Pole Component 29 SlyX PF04102.12 KXS08882.1 - 1.2 9.8 20.8 2.4 8.9 1.4 4.3 1 1 3 4 4 4 0 SlyX ATG16 PF08614.11 KXS08882.1 - 1.6 8.9 22.1 5.4 7.2 22.3 1.7 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.9 KXS08882.1 - 2.8 8.0 20.1 1.2 9.2 16.1 2.0 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 UPF0242 PF06785.11 KXS08882.1 - 4.9 7.2 14.2 7.7 6.6 14.2 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus NDUFB11 PF17250.2 KXS08883.1 - 0.03 15.0 0.2 0.054 14.1 0.2 1.3 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase 11 kDa subunit Rpn9_C PF18261.1 KXS08883.1 - 0.15 11.7 0.2 0.15 11.7 0.2 1.8 2 0 0 2 2 2 0 Rpn9 C-terminal helix DAHP_synth_1 PF00793.20 KXS08884.1 - 1.4e-98 329.2 0.0 1.6e-98 329.0 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family VIR_N PF15912.5 KXS08885.1 - 0.0089 15.7 1.3 1.2 8.7 0.0 3.2 3 0 0 3 3 3 1 Virilizer, N-terminal zf-CCHC PF00098.23 KXS08887.1 - 0.51 10.5 4.1 1.3 9.2 4.1 1.7 1 0 0 1 1 1 0 Zinc knuckle PHD_3 PF13922.6 KXS08887.1 - 1.3 9.4 0.0 1.3 9.4 0.0 3.0 3 1 0 3 3 3 0 PHD domain of transcriptional enhancer, Asx Cellulase PF00150.18 KXS08890.1 - 1.8e-21 76.8 0.1 4e-14 52.7 0.0 2.2 1 1 1 2 2 2 2 Cellulase (glycosyl hydrolase family 5) GlcNAc PF11397.8 KXS08892.1 - 3.5e-21 76.0 0.0 4.8e-21 75.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase (GlcNAc) NIR_SIR_ferr PF03460.17 KXS08892.1 - 0.073 12.9 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 Nitrite/Sulfite reductase ferredoxin-like half domain SWIB PF02201.18 KXS08893.1 - 0.0079 16.1 0.1 0.16 11.9 0.0 2.4 1 1 1 2 2 2 1 SWIB/MDM2 domain NPR3 PF03666.13 KXS08893.1 - 0.75 8.5 9.1 6 5.5 5.1 2.1 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 RNA_pol_Rpb1_5 PF04998.17 KXS08894.1 - 2.1e-87 293.0 0.3 4.3e-87 291.9 0.3 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.12 KXS08894.1 - 3.3e-82 276.3 0.6 6.5e-82 275.3 0.6 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.20 KXS08894.1 - 1.4e-65 220.6 0.0 3.1e-65 219.4 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 KXS08894.1 - 1.3e-39 135.6 0.4 8.9e-38 129.7 0.1 2.7 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 KXS08894.1 - 3.6e-27 94.4 0.0 1.2e-26 92.8 0.0 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_7 PF04990.12 KXS08894.1 - 1.3e-06 28.4 0.1 4.3e-06 26.8 0.1 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 7 DUF4118 PF13493.6 KXS08896.1 - 0.079 12.8 0.5 0.11 12.2 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4118) UL11 PF11094.8 KXS08896.1 - 0.18 11.7 2.1 0.47 10.4 0.5 2.1 2 0 0 2 2 2 0 Membrane-associated tegument protein Cyclin_N PF00134.23 KXS08897.1 - 2e-16 59.9 0.2 2.5e-13 49.9 0.0 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain Bac_GDH PF05088.12 KXS08898.1 - 0.024 12.2 0.2 0.024 12.1 0.2 1.1 1 0 0 1 1 1 0 Bacterial NAD-glutamate dehydrogenase DUF2318 PF10080.9 KXS08898.1 - 0.029 14.5 0.4 0.056 13.6 0.4 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) TF_Zn_Ribbon PF08271.12 KXS08898.1 - 0.033 13.7 1.9 0.087 12.4 1.9 1.8 1 0 0 1 1 1 0 TFIIB zinc-binding DUF327 PF03885.13 KXS08898.1 - 0.042 13.8 5.0 0.045 13.7 0.1 2.8 3 1 0 3 3 3 0 Protein of unknown function (DUF327) Ribosomal_S27e PF01667.17 KXS08898.1 - 0.069 12.9 2.4 0.08 12.7 1.2 1.7 2 0 0 2 2 2 0 Ribosomal protein S27 RPA_interact_C PF14768.6 KXS08898.1 - 0.079 13.5 0.5 0.21 12.2 0.5 1.8 1 0 0 1 1 1 0 Replication protein A interacting C-terminal A2L_zn_ribbon PF08792.10 KXS08898.1 - 0.13 12.0 2.5 0.25 11.1 2.5 1.5 1 0 0 1 1 1 0 A2L zinc ribbon domain ATP-cone PF03477.16 KXS08899.1 - 5.5e-13 49.3 0.1 1.3e-12 48.1 0.0 1.6 2 0 0 2 2 2 1 ATP cone domain Ribonuc_red_lgN PF00317.21 KXS08899.1 - 5.2e-10 39.2 0.1 1.6e-09 37.6 0.0 1.8 2 0 0 2 2 2 1 Ribonucleotide reductase, all-alpha domain Lipase_GDSL_3 PF14606.6 KXS08899.1 - 0.0061 16.7 0.5 0.59 10.2 0.1 2.2 1 1 1 2 2 2 2 GDSL-like Lipase/Acylhydrolase family DUF1601 PF07671.11 KXS08899.1 - 0.11 12.4 0.1 0.26 11.2 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1601) HNH_5 PF14279.6 KXS08900.1 - 0.016 15.1 0.8 0.3 11.0 0.1 2.7 2 1 1 3 3 3 0 HNH endonuclease LAGLIDADG_WhiA PF14527.6 KXS08900.1 - 0.16 12.1 0.4 0.36 10.9 0.4 1.5 1 0 0 1 1 1 0 WhiA LAGLIDADG-like domain NUDIX PF00293.28 KXS08901.1 - 3.3e-07 30.4 0.0 4.9e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Pkinase PF00069.25 KXS08902.1 - 4.4e-20 72.1 0.0 4.7e-20 72.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KXS08902.1 - 1.6e-08 33.8 0.3 1.7e-08 33.7 0.3 1.0 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_Tyr PF07714.17 KXS08902.1 - 4.1e-08 32.8 0.0 4.5e-08 32.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KXS08902.1 - 0.00012 21.5 0.1 0.00015 21.2 0.1 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KXS08902.1 - 0.0041 16.7 0.0 0.0048 16.5 0.0 1.1 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 KXS08902.1 - 0.012 15.5 0.0 0.016 15.2 0.0 1.1 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 KXS08902.1 - 0.02 14.5 0.0 0.027 14.1 0.0 1.2 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 YrbL-PhoP_reg PF10707.9 KXS08902.1 - 0.035 13.6 0.0 0.043 13.3 0.0 1.1 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Glyco_hydro_114 PF03537.13 KXS08903.1 - 2.3e-43 148.2 0.0 2.6e-43 148.0 0.0 1.0 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 F-box-like PF12937.7 KXS08904.1 - 0.016 15.1 0.3 0.045 13.6 0.3 1.8 1 0 0 1 1 1 0 F-box-like DUF1738 PF08401.11 KXS08905.1 - 0.15 12.2 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1738) JmjC PF02373.22 KXS08906.1 - 2.3e-09 37.7 0.0 4.7e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase SDH_C PF18317.1 KXS08906.1 - 0.015 15.1 0.2 0.026 14.3 0.2 1.4 1 0 0 1 1 1 0 Shikimate 5'-dehydrogenase C-terminal domain Cupin_2 PF07883.11 KXS08906.1 - 0.055 13.2 0.0 0.18 11.5 0.0 1.8 2 0 0 2 2 2 0 Cupin domain C1_2 PF03107.16 KXS08906.1 - 7.8 6.9 12.6 3.3 8.1 7.0 2.5 2 0 0 2 2 2 0 C1 domain zf-CCHC PF00098.23 KXS08907.1 - 0.14 12.3 5.5 0.47 10.6 5.5 1.8 1 1 0 1 1 1 0 Zinc knuckle Ndc1_Nup PF09531.10 KXS08909.1 - 4.3 5.9 6.9 6 5.4 6.9 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup mRNA_cap_enzyme PF01331.19 KXS08911.1 - 4.7e-20 72.2 0.0 1.2e-19 70.9 0.0 1.8 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain Pox_MCEL PF03291.16 KXS08911.1 - 3.2e-19 69.2 0.2 9.8e-19 67.6 0.0 1.8 2 0 0 2 2 2 1 mRNA capping enzyme Methyltransf_25 PF13649.6 KXS08911.1 - 2.3e-08 34.6 0.0 9.6e-08 32.6 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXS08911.1 - 1.1e-07 32.4 0.0 2.6e-07 31.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXS08911.1 - 5.3e-07 30.3 0.9 1.6e-05 25.6 0.0 3.2 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXS08911.1 - 2.4e-06 27.4 1.6 2.3e-05 24.3 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain mRNA_cap_C PF03919.15 KXS08911.1 - 7.4e-06 26.6 0.1 7.4e-06 26.6 0.1 2.3 2 0 0 2 2 2 1 mRNA capping enzyme, C-terminal domain RNA_ligase PF09414.10 KXS08911.1 - 1.3e-05 25.6 0.5 0.00012 22.5 0.0 2.6 3 0 0 3 3 3 1 RNA ligase Pox_ATPase-GT PF10640.9 KXS08911.1 - 0.0096 14.8 1.3 0.17 10.7 0.2 2.3 1 1 1 2 2 2 1 mRNA capping enzyme N-terminal, ATPase and guanylyltransferase Pkinase PF00069.25 KXS08912.1 - 1.1e-53 182.3 0.0 1.3e-53 182.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS08912.1 - 1.1e-35 123.3 0.0 1.2e-35 123.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXS08912.1 - 3.2e-09 36.5 0.0 4.2e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 KXS08912.1 - 0.0009 18.4 0.0 0.0016 17.6 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 RIO1 PF01163.22 KXS08912.1 - 0.0095 15.5 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 KXS08912.1 - 0.015 15.3 0.1 0.094 12.6 0.1 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KXS08912.1 - 0.023 13.6 0.1 0.038 12.9 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 KXS08912.1 - 0.044 13.1 0.0 0.084 12.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KXS08912.1 - 0.055 12.2 0.2 0.063 12.0 0.2 1.2 1 0 0 1 1 1 0 Fungal protein kinase SWIB PF02201.18 KXS08913.1 - 2.6e-15 56.1 0.0 5.1e-15 55.1 0.0 1.5 1 0 0 1 1 1 1 SWIB/MDM2 domain Ufd2P_core PF10408.9 KXS08914.1 - 0.009 14.7 0.3 0.009 14.7 0.3 1.5 2 0 0 2 2 2 1 Ubiquitin elongating factor core SOGA PF11365.8 KXS08914.1 - 0.33 12.1 13.0 0.47 11.6 1.0 2.8 2 0 0 2 2 2 0 Protein SOGA KxDL PF10241.9 KXS08914.1 - 1.3 9.3 12.7 1.3 9.3 6.1 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein Nup54 PF13874.6 KXS08914.1 - 2.4 8.3 16.4 2.8 8.0 3.1 2.5 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 APG6_N PF17675.1 KXS08914.1 - 7.2 7.2 16.4 3.4 8.2 5.0 2.8 2 1 0 2 2 2 0 Apg6 coiled-coil region BRE1 PF08647.11 KXS08914.1 - 9 6.4 19.8 0.41 10.8 2.1 3.2 2 1 0 3 3 3 0 BRE1 E3 ubiquitin ligase zf-C2H2_4 PF13894.6 KXS08915.1 - 0.038 14.8 0.1 0.16 12.8 0.1 2.2 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KXS08915.1 - 0.065 13.7 0.1 0.18 12.3 0.1 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type Dimer_Tnp_hAT PF05699.14 KXS08916.1 - 3.9e-13 49.0 0.0 4.4e-13 48.8 0.0 1.1 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Clat_adaptor_s PF01217.20 KXS08917.1 - 6.6e-16 58.5 0.0 2.7e-14 53.3 0.0 2.0 1 1 0 1 1 1 1 Clathrin adaptor complex small chain AP-5_subunit_s1 PF15001.6 KXS08917.1 - 0.048 13.7 0.0 0.07 13.1 0.0 1.2 1 0 0 1 1 1 0 AP-5 complex subunit sigma-1 SBDS PF01172.18 KXS08918.1 - 1e-13 51.2 0.0 1.5e-13 50.6 0.0 1.2 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein Ribosomal_S17e PF00833.18 KXS08919.1 - 1.3e-50 170.4 2.0 2.1e-50 169.7 2.0 1.3 1 0 0 1 1 1 1 Ribosomal S17 Tmemb_55A PF09788.9 KXS08920.1 - 0.091 11.8 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 55A DUF1180 PF06679.12 KXS08920.1 - 0.24 11.8 1.8 0.67 10.3 1.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) RabGAP-TBC PF00566.18 KXS08921.1 - 1.1e-12 48.0 0.0 9.9e-06 25.4 0.0 3.7 4 0 0 4 4 4 2 Rab-GTPase-TBC domain Dcc1 PF09724.9 KXS08922.1 - 0.056 12.7 0.0 0.089 12.1 0.0 1.2 1 0 0 1 1 1 0 Sister chromatid cohesion protein Dcc1 G-alpha PF00503.20 KXS08923.1 - 7.2e-121 403.7 5.5 8.3e-121 403.5 5.5 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KXS08923.1 - 7.7e-16 58.0 0.9 9.9e-11 41.4 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family zf-CHC2 PF01807.20 KXS08923.1 - 0.00025 20.8 0.1 0.0012 18.6 0.0 2.0 2 0 0 2 2 2 1 CHC2 zinc finger Gtr1_RagA PF04670.12 KXS08923.1 - 0.0016 17.8 3.8 0.12 11.7 0.3 2.7 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region AAA_15 PF13175.6 KXS08923.1 - 0.003 17.3 0.3 0.0069 16.1 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain Roc PF08477.13 KXS08923.1 - 0.0042 17.3 1.2 1.7 8.9 0.0 2.8 3 0 0 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 KXS08923.1 - 0.0073 16.0 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain MCM PF00493.23 KXS08923.1 - 0.056 12.5 0.0 0.12 11.5 0.0 1.5 1 0 0 1 1 1 0 MCM P-loop domain FtsK_SpoIIIE PF01580.18 KXS08923.1 - 0.06 12.7 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family MMR_HSR1 PF01926.23 KXS08923.1 - 0.096 12.8 0.0 12 6.0 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF1713 PF08213.11 KXS08924.1 - 0.00083 19.2 16.1 0.0016 18.3 16.1 1.4 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) Ras PF00071.22 KXS08925.1 - 8.4e-51 171.8 0.0 9.9e-51 171.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXS08925.1 - 1.8e-18 66.9 0.0 2.9e-18 66.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXS08925.1 - 2e-10 40.4 0.0 2.5e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KXS08925.1 - 2e-09 37.3 0.2 7.1e-09 35.5 0.2 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KXS08925.1 - 7.6e-06 25.9 0.4 0.0055 16.6 0.0 2.2 1 1 1 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KXS08925.1 - 2.5e-05 24.3 0.1 4e-05 23.7 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.18 KXS08925.1 - 0.033 13.5 0.1 0.084 12.1 0.1 1.6 1 0 0 1 1 1 0 Septin Retrotran_gag_2 PF14223.6 KXS08926.1 - 0.18 11.5 0.0 0.19 11.4 0.0 1.1 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type LRR_4 PF12799.7 KXS08928.1 - 5.5e-27 93.4 53.3 2e-07 31.2 0.9 8.5 4 2 2 8 8 8 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXS08928.1 - 5.5e-15 54.9 51.3 0.00064 19.4 5.4 8.0 2 1 7 9 9 9 8 Leucine rich repeat LRR_1 PF00560.33 KXS08928.1 - 9.8e-13 46.8 41.1 0.22 12.2 0.2 14.1 12 2 1 13 13 13 3 Leucine Rich Repeat LRR_6 PF13516.6 KXS08928.1 - 1.4e-11 43.4 46.4 5.4 7.3 0.3 14.2 15 0 0 15 15 15 7 Leucine Rich repeat SH3_9 PF14604.6 KXS08928.1 - 0.0045 16.8 0.0 0.04 13.8 0.0 2.4 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 KXS08928.1 - 0.0082 15.8 0.0 0.018 14.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXS08928.1 - 0.012 15.1 0.0 0.027 14.1 0.0 1.5 1 0 0 1 1 1 0 SH3 domain DUF2749 PF10907.8 KXS08929.1 - 0.46 10.7 2.0 1.2 9.4 2.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2749) Prim-Pol PF09250.11 KXS08931.1 - 1.4e-19 71.0 0.7 2.2e-19 70.3 0.1 1.5 2 0 0 2 2 2 1 Bifunctional DNA primase/polymerase, N-terminal Replicase PF03090.17 KXS08931.1 - 0.041 13.7 0.0 0.068 13.0 0.0 1.3 1 0 0 1 1 1 0 Replicase family Pkinase PF00069.25 KXS08934.1 - 0.0002 20.8 0.0 0.71 9.2 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXS08934.1 - 0.015 14.6 0.0 2.2 7.5 0.0 2.4 2 0 0 2 2 2 0 Protein tyrosine kinase IL17R_fnIII_D1 PF16556.5 KXS08934.1 - 0.023 14.4 0.1 0.15 11.7 0.0 2.1 2 0 0 2 2 2 0 Interleukin-17 receptor, fibronectin-III-like domain 1 MFS_1 PF07690.16 KXS08937.1 - 9.4e-22 77.4 11.3 9.4e-22 77.4 11.3 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KXS08937.1 - 1.5e-08 33.6 9.8 1.7e-08 33.4 9.8 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KXS08937.1 - 0.00044 19.2 13.2 0.00044 19.2 13.2 2.6 1 1 0 1 1 1 1 Sugar (and other) transporter DUF4149 PF13664.6 KXS08937.1 - 0.23 11.8 8.5 0.36 11.2 4.5 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4149) DNA_binding_1 PF01035.20 KXS08938.1 - 1.4e-19 70.0 0.1 2e-19 69.5 0.1 1.2 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Fungal_trans PF04082.18 KXS08939.1 - 0.0015 17.6 0.3 0.0027 16.8 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 KXS08940.1 - 3.6e-31 108.4 33.0 4.4e-30 104.8 33.0 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXS08940.1 - 2.9e-11 42.9 17.6 1.8e-09 37.0 8.9 3.1 2 1 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.13 KXS08940.1 - 4e-05 22.2 12.6 0.0044 15.5 12.6 2.0 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 KXS08941.1 - 0.0021 17.0 10.3 0.0023 16.9 10.3 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Trp_oprn_chp PF09534.10 KXS08943.1 - 0.024 14.4 0.6 0.04 13.7 0.1 1.5 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) zinc_ribbon_2 PF13240.6 KXS08944.1 - 0.038 13.7 0.8 0.038 13.7 0.8 4.0 4 0 0 4 4 4 0 zinc-ribbon domain SH3_9 PF14604.6 KXS08946.1 - 2e-05 24.3 0.0 0.0004 20.2 0.0 2.3 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 KXS08946.1 - 0.026 14.1 0.0 0.049 13.2 0.0 1.5 1 0 0 1 1 1 0 SH3 domain HSP70 PF00012.20 KXS08947.1 - 3.5e-13 48.6 0.0 4.8e-13 48.2 0.0 1.1 1 0 0 1 1 1 1 Hsp70 protein BcrAD_BadFG PF01869.20 KXS08947.1 - 0.03 13.8 0.1 7.1 6.0 0.1 2.4 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family D5_N PF08706.11 KXS08949.1 - 2.1e-10 41.1 0.0 6.9e-10 39.4 0.0 2.0 1 0 0 1 1 1 1 D5 N terminal like PPL4 PF18188.1 KXS08949.1 - 0.16 11.9 0.8 1.2 9.1 0.8 2.2 1 1 0 1 1 1 0 Prim-pol 4 Ribonuc_red_sm PF00268.21 KXS08949.1 - 0.38 10.2 2.7 12 5.2 0.2 2.6 3 0 0 3 3 3 0 Ribonucleotide reductase, small chain Glyco_hydro_16 PF00722.21 KXS08950.1 - 5.1e-16 58.6 3.0 8.6e-16 57.9 3.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.15 KXS08950.1 - 6.2e-09 34.8 2.1 0.00045 18.7 0.1 2.2 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) DUF1080 PF06439.11 KXS08950.1 - 0.00028 21.1 2.1 0.0004 20.6 2.1 1.2 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1080) SKG6 PF08693.10 KXS08952.1 - 0.018 14.4 2.5 0.04 13.3 2.5 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain CcmF_C PF16327.5 KXS08952.1 - 0.22 10.8 0.9 0.3 10.3 0.9 1.1 1 0 0 1 1 1 0 Cytochrome c-type biogenesis protein CcmF C-terminal SH3_9 PF14604.6 KXS08953.1 - 3e-06 27.0 0.0 6.3e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KXS08953.1 - 0.016 14.8 0.1 0.037 13.7 0.1 1.5 1 0 0 1 1 1 0 Variant SH3 domain Podoplanin PF05808.11 KXS08953.1 - 0.18 11.9 10.1 20 5.2 10.1 2.6 1 1 0 1 1 1 0 Podoplanin SH3_1 PF00018.28 KXS08953.1 - 0.2 11.3 0.0 0.34 10.6 0.0 1.4 1 0 0 1 1 1 0 SH3 domain TMEM154 PF15102.6 KXS08953.1 - 0.24 11.3 5.0 1.6 8.6 0.0 2.7 1 1 1 2 2 2 0 TMEM154 protein family Ank_2 PF12796.7 KXS08955.1 - 1.2e-35 121.9 0.6 1.8e-12 47.7 0.0 4.1 1 1 4 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXS08955.1 - 7.1e-20 71.1 3.6 1.5e-06 28.6 0.1 5.2 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXS08955.1 - 2.3e-18 64.4 2.1 0.0041 17.5 0.0 7.9 8 0 0 8 8 8 4 Ankyrin repeat Ank_5 PF13857.6 KXS08955.1 - 1.5e-16 60.2 7.5 0.0013 18.9 0.0 7.4 4 1 4 8 8 8 4 Ankyrin repeats (many copies) Ank PF00023.30 KXS08955.1 - 3.1e-09 36.9 7.6 0.079 13.4 0.1 7.5 8 0 0 8 8 8 2 Ankyrin repeat DnaJ_C PF01556.18 KXS08955.1 - 0.1 12.7 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 DnaJ C terminal domain Ank_2 PF12796.7 KXS08956.1 - 1.9e-07 31.6 0.0 1e-06 29.2 0.0 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXS08956.1 - 0.00037 20.7 0.1 17 6.4 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 KXS08956.1 - 0.00092 19.7 0.2 0.092 13.4 0.0 2.7 1 1 2 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXS08956.1 - 0.002 18.4 0.1 1.2 9.5 0.0 2.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Clat_adaptor_s PF01217.20 KXS08957.1 - 3.6e-13 49.6 0.0 1.7e-11 44.2 0.0 2.0 1 1 0 1 1 1 1 Clathrin adaptor complex small chain AP-5_subunit_s1 PF15001.6 KXS08957.1 - 0.038 14.0 0.0 0.052 13.6 0.0 1.2 1 0 0 1 1 1 0 AP-5 complex subunit sigma-1 SBDS PF01172.18 KXS08958.1 - 8.5e-13 48.2 0.0 1.2e-12 47.7 0.0 1.2 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein Ribosomal_S17e PF00833.18 KXS08959.1 - 3.1e-51 172.4 1.5 3.6e-51 172.2 1.5 1.0 1 0 0 1 1 1 1 Ribosomal S17 WES_acyltransf PF03007.16 KXS08960.1 - 4.4e-24 85.7 0.1 2e-20 73.7 0.0 2.2 2 0 0 2 2 2 2 Wax ester synthase-like Acyl-CoA acyltransferase domain DUF1298 PF06974.13 KXS08960.1 - 1e-11 45.0 0.0 1.8e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1298) DUF3402 PF11882.8 KXS08961.1 - 2.7e-84 283.9 0.0 5.5e-84 282.9 0.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.13 KXS08961.1 - 2.5e-54 184.4 0.0 4.3e-54 183.7 0.0 1.3 1 0 0 1 1 1 1 N1221-like protein DUF1992 PF09350.10 KXS08962.1 - 2.1e-16 59.8 0.1 3.7e-16 59.0 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1992) MFS_1 PF07690.16 KXS08963.1 - 8.8e-34 117.0 58.1 2.2e-25 89.4 30.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KXS08963.1 - 9.1e-08 31.1 25.2 1.2e-05 24.0 14.0 2.2 1 1 1 2 2 2 2 MFS/sugar transport protein MFS_1 PF07690.16 KXS08964.1 - 1.4e-47 162.3 52.2 2.6e-45 154.9 31.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXS08964.1 - 1.1e-13 50.9 28.6 1.2e-12 47.4 28.6 2.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.6 KXS08964.1 - 3.9e-06 25.7 4.0 3.9e-06 25.7 4.0 3.5 2 2 1 3 3 3 2 MFS/sugar transport protein TRI12 PF06609.13 KXS08964.1 - 1.3e-05 23.9 6.7 1.3e-05 23.9 6.7 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 KXS08964.1 - 3.6e-05 22.4 5.8 3.6e-05 22.4 5.8 1.8 2 0 0 2 2 2 1 Transmembrane secretion effector ESSS PF10183.9 KXS08964.1 - 0.3 11.3 3.7 1.2 9.3 0.2 3.0 3 0 0 3 3 3 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) OATP PF03137.20 KXS08964.1 - 1.2 7.3 12.4 0.58 8.4 0.5 3.2 1 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Peptidase_S9 PF00326.21 KXS08965.1 - 3.6e-41 141.0 0.0 6.6e-41 140.1 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 KXS08965.1 - 1.5e-07 31.2 0.0 7.1e-07 29.0 0.0 1.9 1 1 0 1 1 1 1 Dienelactone hydrolase family PD40 PF07676.12 KXS08965.1 - 1.1e-06 28.4 2.8 0.0075 16.2 0.3 2.7 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat Hydrolase_4 PF12146.8 KXS08965.1 - 1e-05 25.0 0.0 0.049 12.9 0.0 2.4 2 0 0 2 2 2 2 Serine aminopeptidase, S33 COesterase PF00135.28 KXS08965.1 - 0.00083 18.3 0.0 0.0013 17.7 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family LIP PF03583.14 KXS08965.1 - 0.0026 17.1 0.3 0.32 10.3 0.3 2.2 1 1 1 2 2 2 1 Secretory lipase Abhydrolase_3 PF07859.13 KXS08965.1 - 0.0034 17.3 0.0 0.015 15.2 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 KXS08965.1 - 0.0048 16.6 0.0 2.3 7.8 0.1 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold BAAT_C PF08840.11 KXS08965.1 - 0.0056 16.6 0.0 0.055 13.4 0.0 2.1 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal AXE1 PF05448.12 KXS08965.1 - 0.015 14.0 0.5 0.25 10.0 0.5 2.2 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) Abhydrolase_4 PF08386.10 KXS08965.1 - 0.063 13.4 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein Dimer_Tnp_hAT PF05699.14 KXS08966.1 - 1.3e-11 44.1 0.1 1.4e-11 44.0 0.1 1.0 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Cofac_haem_bdg PF04187.13 KXS08969.1 - 1.9e-05 24.8 0.1 0.074 13.0 0.0 2.4 2 0 0 2 2 2 2 Haem-binding uptake, Tiki superfamily, ChaN JIP_LZII PF16471.5 KXS08970.1 - 0.0021 18.2 1.2 0.003 17.7 1.2 1.3 1 0 0 1 1 1 1 JNK-interacting protein leucine zipper II HALZ PF02183.18 KXS08970.1 - 0.0043 17.2 3.8 0.008 16.4 3.8 1.4 1 0 0 1 1 1 1 Homeobox associated leucine zipper Cep57_CLD_2 PF14197.6 KXS08970.1 - 0.015 15.3 5.6 0.026 14.6 5.6 1.3 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 NRBF2 PF08961.10 KXS08970.1 - 0.018 14.7 1.5 0.025 14.2 1.5 1.1 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator DivIC PF04977.15 KXS08970.1 - 0.021 14.6 3.4 0.032 14.0 3.4 1.3 1 0 0 1 1 1 0 Septum formation initiator YabA PF06156.13 KXS08970.1 - 0.021 15.4 0.3 0.034 14.8 0.3 1.2 1 0 0 1 1 1 0 Initiation control protein YabA ParBc PF02195.18 KXS08970.1 - 0.081 13.2 0.1 0.43 10.9 0.0 2.0 2 0 0 2 2 2 0 ParB-like nuclease domain Shugoshin_N PF07558.11 KXS08970.1 - 0.091 12.7 3.8 0.15 11.9 3.8 1.3 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region Rootletin PF15035.6 KXS08970.1 - 0.098 12.7 2.3 0.14 12.1 2.3 1.1 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion XRCC4 PF06632.12 KXS08970.1 - 0.15 10.9 1.6 0.21 10.4 1.6 1.1 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 ZapB PF06005.12 KXS08970.1 - 0.16 12.4 4.8 0.28 11.6 4.8 1.3 1 0 0 1 1 1 0 Cell division protein ZapB APG6_N PF17675.1 KXS08970.1 - 0.22 12.0 5.0 0.31 11.6 5.0 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF2381 PF09544.10 KXS08970.1 - 0.42 10.1 3.2 0.55 9.7 3.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2381) NYD-SP28_assoc PF14775.6 KXS08970.1 - 0.48 10.6 5.4 0.93 9.6 5.4 1.4 1 0 0 1 1 1 0 Sperm tail C-terminal domain APC_N_CC PF16689.5 KXS08970.1 - 0.66 10.1 5.2 2.4 8.3 5.2 1.9 1 1 0 1 1 1 0 Coiled-coil N-terminus of APC, dimerisation domain MctB PF11382.8 KXS08970.1 - 0.67 9.6 1.5 0.94 9.1 1.5 1.1 1 0 0 1 1 1 0 Copper transport outer membrane protein, MctB HNH PF01844.23 KXS08971.1 - 0.00077 19.6 0.7 0.48 10.6 0.0 3.0 2 0 0 2 2 2 2 HNH endonuclease HNH_4 PF13395.6 KXS08971.1 - 0.096 12.6 0.1 2.5 8.1 0.1 3.0 3 0 0 3 3 3 0 HNH endonuclease RecO_N_2 PF13114.6 KXS08971.1 - 0.17 11.6 0.1 0.55 10.0 0.1 1.8 1 0 0 1 1 1 0 RecO N terminal HNH_5 PF14279.6 KXS08971.1 - 0.33 10.8 10.1 0.81 9.6 0.1 4.0 4 0 0 4 4 4 0 HNH endonuclease SPT6_acidic PF14632.6 KXS08971.1 - 1.2 9.8 8.8 0.14 12.8 2.9 2.5 2 0 0 2 2 2 0 Acidic N-terminal SPT6 Capsid_N PF16903.5 KXS08972.1 - 1.9e-51 174.7 0.0 2.6e-51 174.2 0.0 1.2 1 0 0 1 1 1 1 Major capsid protein N-terminus Capsid_NCLDV PF04451.12 KXS08972.1 - 1e-46 159.2 0.1 8.4e-46 156.2 0.1 2.1 2 0 0 2 2 2 1 Large eukaryotic DNA virus major capsid protein Jnk-SapK_ap_N PF09744.9 KXS08973.1 - 0.021 15.0 6.0 0.021 15.0 6.0 2.3 3 0 0 3 3 3 0 JNK_SAPK-associated protein-1 GntR PF00392.21 KXS08973.1 - 0.082 12.6 0.0 0.26 11.0 0.0 1.9 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family FlxA PF14282.6 KXS08973.1 - 3 7.9 13.7 0.19 11.7 7.0 2.4 2 0 0 2 2 2 0 FlxA-like protein Glyco_hydro_18 PF00704.28 KXS08974.1 - 1.7e-16 60.9 0.2 2.6e-16 60.2 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Serglycin PF04360.12 KXS08974.1 - 1.4 8.8 8.4 1.1 9.1 6.7 1.7 2 0 0 2 2 2 0 Serglycin ResIII PF04851.15 KXS08976.1 - 4.6e-22 78.8 0.0 5e-21 75.4 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 KXS08976.1 - 8.4e-05 21.4 0.0 0.00013 20.8 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.29 KXS08976.1 - 0.00015 21.6 0.0 0.00045 20.0 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase MtrG PF04210.13 KXS08976.1 - 0.07 13.0 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit G LCD1 PF09798.9 KXS08976.1 - 0.15 10.6 0.1 0.24 9.9 0.1 1.2 1 0 0 1 1 1 0 DNA damage checkpoint protein Glyco_hydro_18 PF00704.28 KXS08977.1 - 9.5e-09 35.4 1.1 1.3e-08 34.9 1.1 1.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 OTU PF02338.19 KXS08978.1 - 5.3e-08 33.4 0.0 2.2e-07 31.4 0.0 1.8 2 0 0 2 2 2 1 OTU-like cysteine protease bZIP_1 PF00170.21 KXS08978.1 - 0.012 15.7 4.1 0.022 14.9 4.1 1.3 1 0 0 1 1 1 0 bZIP transcription factor DUF1104 PF06518.11 KXS08978.1 - 0.017 15.5 0.4 3.3 8.1 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1104) DivIC PF04977.15 KXS08978.1 - 0.033 14.0 0.9 0.059 13.1 0.9 1.3 1 0 0 1 1 1 0 Septum formation initiator bZIP_2 PF07716.15 KXS08978.1 - 0.15 12.2 7.6 0.25 11.5 7.6 1.3 1 0 0 1 1 1 0 Basic region leucine zipper HSP20 PF00011.21 KXS08979.1 - 1.3e-17 63.8 0.7 1.2e-14 54.3 0.7 2.1 1 1 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KXS08979.1 - 5.7e-09 35.4 0.1 2.2e-08 33.5 0.1 1.9 1 1 0 1 1 1 1 HSP20-like domain found in ArsA Flavi_glycop_C PF02832.16 KXS08979.1 - 0.16 12.2 1.1 0.64 10.2 0.2 2.3 1 1 2 3 3 3 0 Flavivirus glycoprotein, immunoglobulin-like domain VWA_2 PF13519.6 KXS08981.1 - 0.00055 20.5 0.0 0.0012 19.5 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 KXS08981.1 - 0.013 15.5 0.0 0.044 13.7 0.0 1.9 2 0 0 2 2 2 0 von Willebrand factor type A domain VWA PF00092.28 KXS08981.1 - 0.051 13.8 0.0 0.098 12.9 0.0 1.5 1 0 0 1 1 1 0 von Willebrand factor type A domain Peptidase_M19 PF01244.21 KXS08983.1 - 2.2e-06 27.1 0.0 0.0035 16.6 0.0 2.3 2 0 0 2 2 2 2 Membrane dipeptidase (Peptidase family M19) Acyltransferase PF01553.21 KXS08984.1 - 1.1e-21 76.9 0.0 1.6e-21 76.4 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Phage_holin_2_4 PF16082.5 KXS08985.1 - 0.86 9.4 5.7 0.099 12.4 0.5 2.0 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like Pkinase PF00069.25 KXS08988.1 - 3.5e-46 157.7 0.0 6.9e-46 156.7 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS08988.1 - 1.4e-30 106.4 0.0 8.3e-30 103.9 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXS08988.1 - 0.00084 18.7 0.0 0.0013 18.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KXS08988.1 - 0.0011 17.8 0.0 0.0038 16.0 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase RIO1 PF01163.22 KXS08988.1 - 0.0037 16.9 0.0 0.0072 15.9 0.0 1.5 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 KXS08988.1 - 0.028 14.4 0.0 0.055 13.4 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KXS08988.1 - 0.031 13.2 0.0 0.047 12.6 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain adh_short PF00106.25 KXS08989.1 - 3.6e-34 117.9 0.1 6.9e-34 117.0 0.1 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXS08989.1 - 5.7e-30 104.6 0.0 1.5e-29 103.2 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXS08989.1 - 7.9e-07 29.2 2.1 5.9e-06 26.3 0.4 2.4 2 1 0 2 2 2 1 KR domain 3Beta_HSD PF01073.19 KXS08989.1 - 0.0012 17.9 0.3 0.0019 17.3 0.3 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family ADH_zinc_N PF00107.26 KXS08989.1 - 0.011 15.7 0.3 0.017 15.1 0.3 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase NmrA PF05368.13 KXS08989.1 - 0.14 11.7 1.2 0.21 11.1 1.2 1.2 1 0 0 1 1 1 0 NmrA-like family Epimerase PF01370.21 KXS08989.1 - 0.14 11.6 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Rieske PF00355.26 KXS08990.1 - 6.1e-06 26.1 0.0 9.9e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 KXS08990.1 - 0.00034 20.5 0.0 0.00084 19.2 0.0 1.7 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain GIDA PF01134.22 KXS08991.1 - 0.064 12.3 0.0 0.087 11.9 0.0 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A FMO-like PF00743.19 KXS08991.1 - 0.075 11.4 0.0 0.083 11.3 0.0 1.2 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like E1-E2_ATPase PF00122.20 KXS08992.1 - 1.1e-51 174.9 4.7 1.1e-51 174.9 4.7 2.7 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KXS08992.1 - 3.3e-45 154.0 9.1 3.3e-45 154.0 9.1 2.1 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KXS08992.1 - 2.9e-21 76.7 4.7 1.1e-20 74.8 1.7 3.1 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KXS08992.1 - 6.2e-19 67.4 0.4 3.8e-18 64.9 0.0 2.3 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 KXS08992.1 - 1.3e-18 66.8 0.0 2.6e-18 65.9 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KXS08992.1 - 2.5e-09 37.2 1.4 3.1e-06 27.1 0.9 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 KXS08992.1 - 3.1e-06 27.7 0.0 9.4e-06 26.1 0.0 1.9 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Peripla_BP_4 PF13407.6 KXS08992.1 - 0.033 13.7 0.7 0.17 11.5 0.1 2.2 2 0 0 2 2 2 0 Periplasmic binding protein domain IstB_IS21 PF01695.17 KXS08992.1 - 0.14 11.8 0.0 0.33 10.7 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein WHEP-TRS PF00458.20 KXS08992.1 - 0.28 11.4 2.0 0.53 10.5 0.2 2.3 2 0 0 2 2 2 0 WHEP-TRS domain CBM_1 PF00734.18 KXS08993.1 - 1.8e-19 69.4 36.9 2e-10 40.4 15.0 2.5 2 0 0 2 2 2 2 Fungal cellulose binding domain Toxin_7 PF05980.12 KXS08993.1 - 0.78 10.0 24.5 0.89 9.9 9.5 2.3 2 0 0 2 2 2 0 Toxin 7 DSPc PF00782.20 KXS08994.1 - 1.6e-22 79.7 0.0 2.2e-22 79.3 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KXS08994.1 - 0.012 15.2 0.0 0.019 14.6 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Smg4_UPF3 PF03467.15 KXS08996.1 - 9.7e-26 90.8 0.1 1.1e-25 90.7 0.1 1.0 1 0 0 1 1 1 1 Smg-4/UPF3 family Smg4_UPF3 PF03467.15 KXS08997.1 - 1.7e-13 51.0 0.1 2.1e-13 50.7 0.1 1.1 1 0 0 1 1 1 1 Smg-4/UPF3 family Mg_trans_NIPA PF05653.14 KXS08998.1 - 1.4e-06 27.7 2.2 3.9e-05 22.9 0.2 2.2 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 KXS08998.1 - 1.7e-05 25.0 1.9 1.7e-05 25.0 1.9 3.4 4 0 0 4 4 4 1 EamA-like transporter family PUNUT PF16913.5 KXS08998.1 - 0.0023 17.2 0.2 0.0023 17.2 0.2 1.8 2 0 0 2 2 2 1 Purine nucleobase transmembrane transport TMEM234 PF10639.9 KXS08998.1 - 0.011 15.8 0.2 0.12 12.4 0.0 2.3 2 0 0 2 2 2 0 Putative transmembrane family 234 MccV PF17508.2 KXS08998.1 - 1.3 9.6 6.5 0.67 10.5 1.5 2.7 2 0 0 2 2 2 0 Microcin V bacteriocin TFIIF_alpha PF05793.12 KXS08999.1 - 0.013 14.1 1.9 0.015 13.9 1.9 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) VID27_N PF17748.1 KXS08999.1 - 0.023 14.5 1.2 0.033 14.0 1.2 1.3 1 0 0 1 1 1 0 VID27 N-terminal region GRP PF07172.11 KXS09000.1 - 0.00012 22.7 10.6 0.00014 22.5 10.6 1.1 1 0 0 1 1 1 1 Glycine rich protein family zf-CCHC PF00098.23 KXS09001.1 - 0.0084 16.2 3.0 0.0084 16.2 3.0 1.7 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_4 PF14392.6 KXS09001.1 - 0.061 13.1 0.2 0.088 12.6 0.2 1.2 1 0 0 1 1 1 0 Zinc knuckle Retrotran_gag_2 PF14223.6 KXS09002.1 - 1e-05 25.2 0.4 2e-05 24.3 0.3 1.5 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type Chromo PF00385.24 KXS09003.1 - 7.8e-09 35.3 0.0 9.7e-09 35.0 0.0 1.2 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain FAM76 PF16046.5 KXS09005.1 - 0.00052 19.5 8.2 0.00052 19.5 8.2 2.1 1 1 1 2 2 2 1 FAM76 protein DUF4407 PF14362.6 KXS09005.1 - 0.0045 16.4 8.2 0.008 15.6 8.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) CC2-LZ PF16516.5 KXS09005.1 - 0.01 16.2 9.4 0.13 12.6 3.4 2.9 2 0 0 2 2 2 2 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DYW_deaminase PF14432.6 KXS09005.1 - 0.02 14.8 0.1 0.049 13.5 0.1 1.6 1 0 0 1 1 1 0 DYW family of nucleic acid deaminases SlyX PF04102.12 KXS09005.1 - 0.4 11.3 13.5 0.26 11.9 1.6 3.0 2 0 0 2 2 2 0 SlyX V_ATPase_I PF01496.19 KXS09005.1 - 0.87 7.4 7.7 1.1 7.1 7.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Serine_rich PF08824.10 KXS09005.1 - 1.9 8.5 10.7 4.5 7.3 3.1 2.9 2 1 0 2 2 2 0 Serine rich protein interaction domain ApoC-I PF04691.12 KXS09005.1 - 2.5 8.1 7.2 0.97 9.4 1.2 3.0 3 0 0 3 3 3 0 Apolipoprotein C-I (ApoC-1) N6_N4_Mtase PF01555.18 KXS09006.1 - 0.0071 16.1 0.0 0.016 14.9 0.0 1.6 2 0 0 2 2 2 1 DNA methylase ParBc PF02195.18 KXS09006.1 - 0.032 14.5 0.0 0.1 12.9 0.0 1.8 2 0 0 2 2 2 0 ParB-like nuclease domain ABC_tran PF00005.27 KXS09008.1 - 4.9e-32 111.3 0.1 7.3e-32 110.8 0.1 1.3 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KXS09008.1 - 6.4e-10 38.8 0.5 6e-06 25.9 0.0 2.1 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KXS09008.1 - 6.9e-05 22.8 0.4 0.0071 16.2 0.0 2.8 2 1 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KXS09008.1 - 0.00049 20.5 1.2 0.0021 18.5 1.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 KXS09008.1 - 0.00052 19.9 0.0 0.00088 19.2 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_15 PF13175.6 KXS09008.1 - 0.0019 18.0 0.0 0.0026 17.5 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KXS09008.1 - 0.0028 18.1 0.1 0.036 14.5 0.1 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 KXS09008.1 - 0.0029 17.3 0.2 0.0069 16.1 0.2 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Zeta_toxin PF06414.12 KXS09008.1 - 0.0048 16.2 0.1 0.041 13.2 0.0 2.1 2 0 0 2 2 2 1 Zeta toxin AAA_22 PF13401.6 KXS09008.1 - 0.0087 16.3 0.1 0.053 13.8 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KXS09008.1 - 0.016 15.0 0.2 0.078 12.7 0.2 2.0 1 1 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 KXS09008.1 - 0.027 14.7 0.8 0.25 11.6 0.8 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.14 KXS09008.1 - 0.028 14.4 0.0 0.19 11.7 0.0 2.2 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF815 PF05673.13 KXS09008.1 - 0.068 12.3 0.0 0.58 9.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_18 PF13238.6 KXS09008.1 - 0.071 13.7 0.1 0.54 10.8 0.1 2.2 2 1 1 3 3 3 0 AAA domain AAA_23 PF13476.6 KXS09008.1 - 0.11 13.0 0.0 0.24 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KXS09008.1 - 0.13 12.0 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AMP-binding PF00501.28 KXS09010.1 - 5.9e-74 249.1 0.0 1.2e-73 248.1 0.0 1.5 2 0 0 2 2 2 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXS09010.1 - 1.9e-10 41.5 0.0 6.5e-10 39.9 0.0 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain FGGY_N PF00370.21 KXS09011.1 - 2.6e-11 43.6 0.0 5.8e-07 29.3 0.0 2.9 2 2 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 KXS09011.1 - 8.2e-10 38.7 0.1 2.8e-09 37.0 0.0 1.8 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain Arm PF00514.23 KXS09012.1 - 2.9e-11 43.0 10.3 7.1e-06 25.9 0.4 5.0 4 1 0 4 4 4 2 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 KXS09012.1 - 3.5e-10 40.1 14.2 2.5e-06 27.8 3.4 3.9 2 2 1 4 4 4 3 HEAT repeats HEAT_EZ PF13513.6 KXS09012.1 - 1.1e-08 35.4 14.6 0.014 15.9 0.0 4.8 4 0 0 4 4 4 3 HEAT-like repeat HEAT PF02985.22 KXS09012.1 - 2.6e-08 33.4 13.2 0.081 13.2 0.1 6.3 6 1 1 7 7 7 3 HEAT repeat Adaptin_N PF01602.20 KXS09012.1 - 0.0027 16.4 3.4 0.03 12.9 3.5 2.3 1 1 0 1 1 1 1 Adaptin N terminal region UNC45-central PF11701.8 KXS09012.1 - 0.0041 17.1 0.1 0.33 10.9 0.0 2.2 2 0 0 2 2 2 1 Myosin-binding striated muscle assembly central IFRD PF05004.13 KXS09012.1 - 0.01 15.0 0.4 0.92 8.5 0.1 2.4 2 0 0 2 2 2 0 Interferon-related developmental regulator (IFRD) Cnd1 PF12717.7 KXS09012.1 - 0.011 15.8 0.1 0.71 9.9 0.1 2.7 2 1 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 PUL PF08324.11 KXS09012.1 - 0.011 14.9 1.3 2.4 7.3 0.2 2.6 2 1 1 3 3 3 0 PUL domain RICTOR_N PF14664.6 KXS09012.1 - 0.066 12.2 0.7 4.1 6.3 0.0 3.0 3 1 1 4 4 4 0 Rapamycin-insensitive companion of mTOR, N-term TetR_C_16 PF17920.1 KXS09012.1 - 0.76 10.0 9.0 15 5.9 0.1 3.6 3 1 1 4 4 4 0 Tetracyclin repressor-like, C-terminal domain Methyltr_RsmB-F PF01189.17 KXS09013.1 - 3.1e-23 82.5 0.0 3e-15 56.4 0.0 3.3 2 1 1 3 3 3 2 16S rRNA methyltransferase RsmB/F Methyltransf_31 PF13847.6 KXS09013.1 - 0.032 14.0 0.0 3.4 7.4 0.0 2.4 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.12 KXS09013.1 - 0.033 14.8 0.0 13 6.5 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_25 PF13649.6 KXS09013.1 - 0.052 14.2 0.0 3.6 8.4 0.0 2.6 2 0 0 2 2 2 0 Methyltransferase domain Amino_oxidase PF01593.24 KXS09015.1 - 5.4e-18 65.5 0.0 8.5e-18 64.9 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KXS09015.1 - 6.6e-14 51.9 0.0 1.6e-13 50.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXS09015.1 - 6.4e-07 29.3 3.6 2.8e-05 23.9 0.2 2.4 2 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KXS09015.1 - 0.012 14.7 0.2 0.032 13.3 0.1 1.7 2 0 0 2 2 2 0 FAD binding domain NAD_binding_9 PF13454.6 KXS09015.1 - 0.013 15.5 0.0 0.034 14.2 0.0 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding Thi4 PF01946.17 KXS09015.1 - 0.016 14.5 1.5 0.076 12.3 0.0 2.2 2 0 0 2 2 2 0 Thi4 family Pyr_redox_2 PF07992.14 KXS09015.1 - 0.069 12.4 0.4 0.13 11.4 0.1 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SPX PF03105.19 KXS09016.1 - 1.1e-32 114.5 1.4 2.2e-32 113.4 1.4 1.5 1 1 0 1 1 1 1 SPX domain zf-C3HC4_4 PF15227.6 KXS09016.1 - 1.6e-08 34.6 5.6 4e-08 33.3 5.8 1.6 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 KXS09016.1 - 2.8e-07 30.5 4.3 2.8e-07 30.5 4.3 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KXS09016.1 - 7.7e-07 28.9 5.8 1.3e-06 28.2 5.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXS09016.1 - 1.4e-06 28.2 6.8 2.6e-06 27.3 6.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KXS09016.1 - 2.2e-06 27.4 7.4 3.8e-06 26.7 7.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXS09016.1 - 5.8e-06 26.1 6.8 9.8e-06 25.3 6.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXS09016.1 - 2.8e-05 24.4 9.4 4.8e-05 23.6 9.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_6 PF14835.6 KXS09016.1 - 0.0038 17.1 3.8 0.0076 16.1 3.8 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_10 PF16685.5 KXS09016.1 - 0.018 15.1 4.7 0.035 14.3 4.7 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 Prok-RING_4 PF14447.6 KXS09016.1 - 0.031 14.1 9.3 0.79 9.6 9.6 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 IFT57 PF10498.9 KXS09016.1 - 0.19 10.6 0.5 7.7 5.4 0.1 2.1 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 zf-rbx1 PF12678.7 KXS09016.1 - 1.2 9.5 7.1 3.5 8.0 7.1 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-Nse PF11789.8 KXS09016.1 - 1.4 8.8 4.3 3.7 7.4 4.3 1.8 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.6 KXS09016.1 - 7.4 6.5 7.6 0.66 9.8 2.5 1.7 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Histone PF00125.24 KXS09017.1 - 8.9e-22 77.9 0.8 1.1e-21 77.6 0.8 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KXS09017.1 - 5.5e-05 23.4 0.0 0.00014 22.0 0.0 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KXS09017.1 - 0.0026 18.2 0.0 0.0044 17.5 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A RP-C PF03428.13 KXS09017.1 - 0.085 12.5 0.1 0.22 11.2 0.1 1.6 1 1 0 1 1 1 0 Replication protein C N-terminal domain Histone_H2A_C PF16211.5 KXS09018.1 - 8.2e-20 70.3 1.4 1.4e-19 69.5 1.4 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KXS09018.1 - 4.4e-16 59.4 0.0 4.9e-16 59.3 0.0 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KXS09018.1 - 3.6e-06 27.2 0.0 4.6e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone MRG PF05712.13 KXS09019.1 - 0.081 12.2 0.0 0.094 12.0 0.0 1.2 1 0 0 1 1 1 0 MRG CMD PF02627.20 KXS09021.1 - 5.1e-27 93.8 0.0 2.2e-13 50.1 0.0 2.6 2 0 0 2 2 2 2 Carboxymuconolactone decarboxylase family MOZART1 PF12554.8 KXS09021.1 - 0.015 15.1 0.2 0.71 9.7 0.0 3.0 4 0 0 4 4 4 0 Mitotic-spindle organizing gamma-tubulin ring associated PIF1 PF05970.14 KXS09022.1 - 7.1e-36 124.1 0.3 1.1e-35 123.5 0.3 1.2 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KXS09022.1 - 1.3e-16 60.9 0.0 1.9e-16 60.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KXS09022.1 - 1.6e-11 44.8 0.1 2.6e-11 44.0 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KXS09022.1 - 2.5e-06 27.8 0.1 6.1e-06 26.5 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KXS09022.1 - 0.00031 20.3 0.1 0.0018 17.8 0.1 2.0 2 0 0 2 2 2 1 P-loop containing dynein motor region T2SSE PF00437.20 KXS09022.1 - 0.0015 17.7 0.0 0.0023 17.1 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_5 PF07728.14 KXS09022.1 - 0.0017 18.3 0.1 0.011 15.7 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KXS09022.1 - 0.0037 17.7 0.2 0.0093 16.4 0.1 1.7 2 0 0 2 2 1 1 AAA ATPase domain Mg_chelatase PF01078.21 KXS09022.1 - 0.0043 16.5 0.1 0.0084 15.5 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RsgA_GTPase PF03193.16 KXS09022.1 - 0.0043 17.0 0.0 0.0066 16.4 0.0 1.2 1 0 0 1 1 1 1 RsgA GTPase PhoH PF02562.16 KXS09022.1 - 0.0064 16.0 0.1 0.014 14.8 0.1 1.5 1 0 0 1 1 1 1 PhoH-like protein AAA_11 PF13086.6 KXS09022.1 - 0.0082 16.0 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 KXS09022.1 - 0.0095 15.7 0.1 0.041 13.6 0.1 1.9 2 0 0 2 2 2 1 Sigma-54 interaction domain Helicase_RecD PF05127.14 KXS09022.1 - 0.012 15.5 2.9 0.029 14.2 0.8 2.5 2 1 0 2 2 2 0 Helicase AAA_10 PF12846.7 KXS09022.1 - 0.015 14.3 0.0 0.023 13.6 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain RNA_helicase PF00910.22 KXS09022.1 - 0.018 15.4 0.0 0.087 13.2 0.1 2.2 2 1 0 2 2 1 0 RNA helicase NACHT PF05729.12 KXS09022.1 - 0.046 13.6 0.0 0.082 12.8 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Zeta_toxin PF06414.12 KXS09022.1 - 0.05 12.9 0.0 0.08 12.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_33 PF13671.6 KXS09022.1 - 0.074 13.2 0.1 0.14 12.4 0.1 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KXS09022.1 - 0.077 13.5 0.1 0.16 12.5 0.1 1.5 1 0 0 1 1 1 0 ABC transporter AAA_18 PF13238.6 KXS09022.1 - 0.091 13.3 0.1 0.22 12.1 0.1 1.8 2 0 0 2 2 1 0 AAA domain ATPase_2 PF01637.18 KXS09022.1 - 0.11 12.4 0.0 0.31 10.9 0.0 1.5 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea TsaE PF02367.17 KXS09022.1 - 0.11 12.5 0.1 0.21 11.6 0.1 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 KXS09022.1 - 0.12 12.2 0.0 0.79 9.4 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein Bac_DnaA PF00308.18 KXS09022.1 - 0.12 12.2 0.1 0.42 10.4 0.0 1.8 2 0 0 2 2 2 0 Bacterial dnaA protein Herpes_Helicase PF02689.14 KXS09022.1 - 0.14 10.1 0.0 0.18 9.7 0.0 1.2 1 0 0 1 1 1 0 Helicase TrwB_AAD_bind PF10412.9 KXS09022.1 - 0.14 11.0 0.0 0.23 10.4 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA PF00004.29 KXS09022.1 - 0.15 12.5 0.1 0.26 11.7 0.1 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 KXS09022.1 - 0.19 11.0 0.1 0.31 10.2 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) CENP-F_N PF10481.9 KXS09023.1 - 0.034 13.8 0.0 0.15 11.6 0.0 1.8 2 0 0 2 2 2 0 Cenp-F N-terminal domain Trimer_CC PF08954.11 KXS09023.1 - 0.048 13.2 0.6 0.11 12.0 0.6 1.6 1 0 0 1 1 1 0 Trimerisation motif AAA PF00004.29 KXS09026.1 - 7.4e-37 126.7 0.0 1.1e-36 126.1 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KXS09026.1 - 8.7e-06 25.5 0.1 2.2e-05 24.2 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 KXS09026.1 - 5.3e-05 23.2 0.1 0.00029 20.9 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KXS09026.1 - 7.1e-05 23.3 0.3 0.0032 17.8 0.0 2.7 1 1 2 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 KXS09026.1 - 0.00013 21.7 0.0 0.0011 18.7 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KXS09026.1 - 0.00078 19.7 0.1 0.021 15.1 0.1 2.5 1 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 KXS09026.1 - 0.00081 18.8 0.1 0.0019 17.6 0.1 1.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 KXS09026.1 - 0.0027 17.5 0.0 0.0043 16.8 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.6 KXS09026.1 - 0.0048 17.1 0.2 0.024 14.8 0.0 2.4 2 1 0 2 2 2 1 AAA domain TIP49 PF06068.13 KXS09026.1 - 0.0074 15.5 0.0 0.015 14.6 0.0 1.5 1 1 0 1 1 1 1 TIP49 P-loop domain AAA_2 PF07724.14 KXS09026.1 - 0.011 15.9 0.0 0.14 12.3 0.0 2.4 1 1 1 2 2 2 0 AAA domain (Cdc48 subfamily) AAA_25 PF13481.6 KXS09026.1 - 0.016 14.8 0.3 0.17 11.4 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KXS09026.1 - 0.02 15.5 0.0 0.041 14.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KXS09026.1 - 0.042 13.9 0.0 0.063 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KXS09026.1 - 0.082 12.6 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 KXS09026.1 - 0.085 12.6 0.0 0.29 10.8 0.0 1.8 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_28 PF13521.6 KXS09026.1 - 0.088 13.0 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 KXS09026.1 - 0.14 11.6 0.1 0.28 10.6 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_7 PF12775.7 KXS09026.1 - 0.16 11.5 0.0 0.32 10.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region NACHT PF05729.12 KXS09026.1 - 0.18 11.7 0.1 0.33 10.9 0.1 1.4 1 0 0 1 1 1 0 NACHT domain ATPase PF06745.13 KXS09026.1 - 0.19 11.0 0.0 0.35 10.2 0.0 1.3 1 0 0 1 1 1 0 KaiC RNA_helicase PF00910.22 KXS09026.1 - 0.24 11.8 0.0 0.41 11.0 0.0 1.4 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.27 KXS09028.1 - 4.9e-32 111.3 0.1 7.3e-32 110.8 0.1 1.3 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KXS09028.1 - 6.4e-10 38.8 0.5 6e-06 25.9 0.0 2.1 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KXS09028.1 - 6.9e-05 22.8 0.4 0.0071 16.2 0.0 2.8 2 1 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KXS09028.1 - 0.00049 20.5 1.2 0.0021 18.5 1.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 KXS09028.1 - 0.00052 19.9 0.0 0.00088 19.2 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_15 PF13175.6 KXS09028.1 - 0.0019 18.0 0.0 0.0026 17.5 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KXS09028.1 - 0.0028 18.1 0.1 0.036 14.5 0.1 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 KXS09028.1 - 0.0029 17.3 0.2 0.0069 16.1 0.2 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Zeta_toxin PF06414.12 KXS09028.1 - 0.0048 16.2 0.1 0.041 13.2 0.0 2.1 2 0 0 2 2 2 1 Zeta toxin AAA_22 PF13401.6 KXS09028.1 - 0.0087 16.3 0.1 0.053 13.8 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KXS09028.1 - 0.016 15.0 0.2 0.078 12.7 0.2 2.0 1 1 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 KXS09028.1 - 0.027 14.7 0.8 0.25 11.6 0.8 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.14 KXS09028.1 - 0.028 14.4 0.0 0.19 11.7 0.0 2.2 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF815 PF05673.13 KXS09028.1 - 0.068 12.3 0.0 0.58 9.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_18 PF13238.6 KXS09028.1 - 0.071 13.7 0.1 0.54 10.8 0.1 2.2 2 1 1 3 3 3 0 AAA domain AAA_23 PF13476.6 KXS09028.1 - 0.11 13.0 0.0 0.24 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KXS09028.1 - 0.13 12.0 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Guanylate_kin PF00625.21 KXS09029.1 - 0.092 12.4 0.6 0.17 11.6 0.6 1.3 1 0 0 1 1 1 0 Guanylate kinase Jagunal PF07086.12 KXS09029.1 - 0.1 12.6 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Jagunal, ER re-organisation during oogenesis Skp1 PF01466.19 KXS09029.1 - 0.13 12.4 0.1 0.38 10.9 0.1 1.7 1 0 0 1 1 1 0 Skp1 family, dimerisation domain RNA_helicase PF00910.22 KXS09030.1 - 0.0039 17.6 0.0 0.008 16.6 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_18 PF13238.6 KXS09030.1 - 0.13 12.8 0.1 2.1 8.9 0.1 2.4 1 1 0 1 1 1 0 AAA domain zf-C4H2 PF10146.9 KXS09036.1 - 0.00034 21.0 2.6 0.00051 20.4 2.6 1.3 1 0 0 1 1 1 1 Zinc finger-containing protein CCDC144C PF14915.6 KXS09036.1 - 0.0024 17.0 2.7 0.0035 16.5 2.7 1.2 1 0 0 1 1 1 1 CCDC144C protein coiled-coil region DNA_pol_B_N PF18094.1 KXS09036.1 - 0.013 16.0 0.1 0.039 14.5 0.1 1.8 1 1 0 1 1 1 0 DNA polymerase beta N-terminal domain STAT_alpha PF01017.20 KXS09036.1 - 0.013 15.4 0.9 0.022 14.7 0.9 1.4 1 0 0 1 1 1 0 STAT protein, all-alpha domain GAS PF13851.6 KXS09036.1 - 0.016 14.5 4.1 0.031 13.6 4.1 1.5 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 KXS09036.1 - 0.02 13.8 3.9 0.031 13.2 3.9 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Fez1 PF06818.15 KXS09036.1 - 0.076 13.5 7.6 0.12 12.8 7.6 1.3 1 0 0 1 1 1 0 Fez1 DLP_helical PF18709.1 KXS09036.1 - 0.22 10.7 3.1 0.43 9.7 0.6 2.0 1 1 1 2 2 2 0 Dynamin-like helical domain TMPIT PF07851.13 KXS09036.1 - 0.25 10.5 0.9 0.34 10.1 0.9 1.2 1 0 0 1 1 1 0 TMPIT-like protein CCDC-167 PF15188.6 KXS09036.1 - 0.27 11.6 5.1 0.24 11.8 3.7 1.7 2 0 0 2 2 1 0 Coiled-coil domain-containing protein 167 Golgin_A5 PF09787.9 KXS09036.1 - 0.31 10.5 6.6 0.45 9.9 6.6 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 HAUS5 PF14817.6 KXS09036.1 - 0.52 9.0 8.0 0.61 8.8 8.0 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 ABC_tran_CTD PF16326.5 KXS09036.1 - 0.75 10.1 3.8 4.4 7.6 1.5 2.4 1 1 1 2 2 2 0 ABC transporter C-terminal domain APG6_N PF17675.1 KXS09036.1 - 0.92 10.0 11.4 0.46 11.0 9.0 1.8 2 1 0 2 2 2 0 Apg6 coiled-coil region DUF2235 PF09994.9 KXS09037.1 - 9e-59 199.2 0.0 1.6e-58 198.4 0.0 1.4 1 1 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Trypsin PF00089.26 KXS09038.1 - 0.079 12.8 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Trypsin MFS_1 PF07690.16 KXS09039.1 - 1.7e-24 86.4 33.5 1.7e-24 86.4 33.5 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Dioxygenase_C PF00775.21 KXS09040.1 - 5.9e-05 22.6 0.1 0.0001 21.8 0.1 1.4 1 0 0 1 1 1 1 Dioxygenase SNRNP27 PF08648.12 KXS09042.1 - 0.0026 17.8 0.5 0.0076 16.3 0.5 1.8 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins DUF3883 PF13020.6 KXS09043.1 - 2.3e-05 24.4 0.0 4.5e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3883) COesterase PF00135.28 KXS09045.1 - 7.8e-22 77.8 0.2 9.9e-22 77.5 0.2 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXS09045.1 - 6.2e-06 26.2 0.0 7.6e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KXS09045.1 - 0.0017 17.9 0.1 0.0023 17.4 0.1 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.28 KXS09046.1 - 2.9e-99 333.3 0.0 3.5e-99 333.0 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXS09046.1 - 1.3e-07 31.7 0.1 5.6e-05 23.1 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KXS09046.1 - 0.0026 17.3 0.1 0.0049 16.4 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family PhoLip_ATPase_C PF16212.5 KXS09048.1 - 1.9e-54 185.1 14.7 1.9e-54 185.1 14.7 2.7 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal Hydrolase PF00702.26 KXS09048.1 - 3.1e-12 47.2 0.5 1.2e-07 32.2 1.2 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase PhoLip_ATPase_N PF16209.5 KXS09048.1 - 1.3e-10 40.8 0.1 5.1e-10 38.9 0.0 2.0 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 KXS09048.1 - 4e-09 36.4 0.0 3.7e-08 33.4 0.0 2.4 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 KXS09048.1 - 1.7e-05 24.4 0.0 1.7e-05 24.4 0.0 2.9 3 1 0 3 3 3 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KXS09048.1 - 0.005 16.6 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase F-box-like PF12937.7 KXS09049.1 - 3.3e-08 33.3 1.2 7.5e-08 32.1 1.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXS09049.1 - 0.00025 20.8 0.3 0.00051 19.9 0.3 1.5 1 0 0 1 1 1 1 F-box domain PP2 PF14299.6 KXS09049.1 - 0.0085 16.1 0.0 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 Phloem protein 2 COesterase PF00135.28 KXS09050.1 - 6.4e-92 309.0 0.0 7.9e-92 308.8 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Chitin_bind_1 PF00187.19 KXS09050.1 - 1.5e-07 31.8 20.2 3.4e-07 30.6 20.2 1.6 1 0 0 1 1 1 1 Chitin recognition protein Abhydrolase_3 PF07859.13 KXS09050.1 - 7.7e-07 29.2 0.4 5e-05 23.3 0.0 2.7 3 0 0 3 3 3 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KXS09050.1 - 0.00062 19.3 0.2 0.0013 18.2 0.1 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family Aldedh PF00171.22 KXS09051.1 - 2.3e-154 514.3 0.0 1.2e-153 511.9 0.0 1.8 1 1 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KXS09051.1 - 0.039 13.4 0.0 0.24 10.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) CBM_1 PF00734.18 KXS09052.1 - 1.6e-11 43.9 8.4 1.6e-11 43.9 8.4 3.3 2 0 0 2 2 2 1 Fungal cellulose binding domain Sina PF03145.16 KXS09053.1 - 1.3e-05 25.3 1.4 1.9e-05 24.7 1.4 1.2 1 0 0 1 1 1 1 Seven in absentia protein family DUF1644 PF07800.12 KXS09053.1 - 0.014 15.5 1.9 0.014 15.5 1.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1644) CDKN3 PF05706.12 KXS09053.1 - 0.014 15.1 0.1 0.022 14.4 0.1 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) DUF5316 PF17247.2 KXS09054.1 - 0.0041 17.1 0.0 0.0075 16.3 0.0 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5316) Phage_HK97_TLTM PF06120.11 KXS09054.1 - 0.026 13.7 0.1 0.037 13.2 0.1 1.1 1 0 0 1 1 1 0 Tail length tape measure protein Helicase_C PF00271.31 KXS09055.1 - 8.1e-06 26.2 0.2 2.2e-05 24.8 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain UvrD-helicase PF00580.21 KXS09055.1 - 0.098 12.2 0.1 1.5 8.3 0.1 2.0 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain Phi-29_GP3 PF05435.11 KXS09055.1 - 0.11 12.0 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Phi-29 DNA terminal protein GP3 zf-C3HC4_3 PF13920.6 KXS09055.1 - 0.17 11.8 10.4 0.35 10.8 10.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXS09055.1 - 0.42 10.6 10.4 1.1 9.2 10.4 1.7 1 0 0 1 1 1 0 zinc-RING finger domain DUF3948 PF13134.6 KXS09056.1 - 0.031 14.0 2.7 0.072 12.8 2.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3948) Dimer_Tnp_hAT PF05699.14 KXS09057.1 - 1.2e-18 66.7 0.0 1.4e-18 66.5 0.0 1.1 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Patatin PF01734.22 KXS09059.1 - 7e-17 62.3 1.5 9.6e-15 55.3 1.5 2.1 1 1 0 1 1 1 1 Patatin-like phospholipase TPR_10 PF13374.6 KXS09060.1 - 6.4e-52 172.1 30.4 3.5e-11 42.6 0.2 10.4 9 1 1 10 10 10 8 Tetratricopeptide repeat TPR_12 PF13424.6 KXS09060.1 - 6.6e-50 167.3 32.0 3.7e-12 46.3 0.4 7.2 3 1 5 8 8 7 6 Tetratricopeptide repeat TPR_8 PF13181.6 KXS09060.1 - 6.1e-19 66.6 3.7 0.068 13.4 0.0 9.5 9 1 1 10 10 10 5 Tetratricopeptide repeat TPR_4 PF07721.14 KXS09060.1 - 8e-16 57.0 21.6 0.035 14.7 0.3 8.7 7 1 1 8 8 8 4 Tetratricopeptide repeat TPR_2 PF07719.17 KXS09060.1 - 1.1e-15 56.4 8.4 0.12 12.5 0.0 8.9 10 0 0 10 10 8 5 Tetratricopeptide repeat NB-ARC PF00931.22 KXS09060.1 - 3.8e-15 55.7 0.0 7e-15 54.9 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain TPR_19 PF14559.6 KXS09060.1 - 1.6e-13 51.0 18.1 0.014 15.9 0.1 8.0 4 1 6 10 10 8 3 Tetratricopeptide repeat TPR_1 PF00515.28 KXS09060.1 - 5.1e-13 48.2 5.2 0.4 10.6 0.0 8.9 10 0 0 10 10 8 2 Tetratricopeptide repeat NAPRTase PF04095.16 KXS09060.1 - 2.4e-12 47.0 0.0 5.6e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family TPR_14 PF13428.6 KXS09060.1 - 7.6e-11 41.9 20.8 0.55 11.2 0.1 8.8 8 1 1 9 9 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 KXS09060.1 - 3.1e-10 39.3 12.9 0.46 10.6 0.1 8.4 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_16 PF13432.6 KXS09060.1 - 4.4e-10 40.0 19.8 0.046 14.4 0.2 6.3 3 2 2 5 5 5 5 Tetratricopeptide repeat TPR_20 PF14561.6 KXS09060.1 - 8.4e-10 38.9 18.1 1.2 9.6 0.0 8.1 2 1 6 8 8 8 4 Tetratricopeptide repeat TPR_6 PF13174.6 KXS09060.1 - 5.3e-08 33.0 14.5 0.63 10.8 0.1 9.0 12 1 0 12 12 8 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KXS09060.1 - 6.4e-07 29.5 6.7 4.5 7.6 0.0 7.3 2 1 7 9 9 9 1 Anaphase-promoting complex, cyclosome, subunit 3 AAA_22 PF13401.6 KXS09060.1 - 6.6e-06 26.4 0.0 1.8e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 KXS09060.1 - 0.00016 21.6 0.0 0.00031 20.7 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_25 PF13481.6 KXS09060.1 - 0.00016 21.3 0.4 0.0013 18.4 0.1 2.7 2 1 0 2 2 2 1 AAA domain PPR PF01535.20 KXS09060.1 - 0.00016 21.7 0.0 47 4.6 0.0 6.5 6 0 0 6 6 6 0 PPR repeat PilO PF04350.13 KXS09060.1 - 0.00061 20.0 1.2 24 5.1 0.0 5.0 4 2 3 7 7 6 0 Pilus assembly protein, PilO AAA_16 PF13191.6 KXS09060.1 - 0.0032 17.9 0.5 0.018 15.4 0.5 2.4 1 1 0 1 1 1 1 AAA ATPase domain IstB_IS21 PF01695.17 KXS09060.1 - 0.0065 16.2 0.0 0.025 14.3 0.0 2.0 2 0 0 2 2 2 1 IstB-like ATP binding protein TPR_17 PF13431.6 KXS09060.1 - 0.015 15.6 20.1 0.97 10.0 0.1 7.4 8 0 0 8 8 8 0 Tetratricopeptide repeat SH3_19 PF18597.1 KXS09060.1 - 0.08 12.8 0.0 0.22 11.4 0.0 1.7 1 0 0 1 1 1 0 Myosin X N-terminal SH3 domain AAA_7 PF12775.7 KXS09060.1 - 0.082 12.4 0.0 0.27 10.7 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region LigB PF02900.18 KXS09061.1 - 7.1e-31 107.3 0.0 9e-31 106.9 0.0 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase zf-CDGSH PF09360.10 KXS09062.1 - 1.2e-19 70.3 3.0 4.5e-11 42.8 0.1 2.2 2 0 0 2 2 2 2 Iron-binding zinc finger CDGSH type SKI PF01202.22 KXS09064.1 - 1.5e-05 25.2 0.0 0.0013 18.9 0.0 2.2 1 1 0 1 1 1 1 Shikimate kinase AAA_28 PF13521.6 KXS09064.1 - 6.9e-05 23.1 0.3 0.00015 22.1 0.3 1.9 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KXS09064.1 - 0.00014 22.1 0.0 0.00019 21.6 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KXS09064.1 - 0.0007 20.2 0.0 0.0023 18.5 0.0 1.8 1 1 1 2 2 2 1 AAA domain Cytidylate_kin PF02224.18 KXS09064.1 - 0.0012 18.6 0.0 0.0019 18.0 0.0 1.3 1 0 0 1 1 1 1 Cytidylate kinase AAA PF00004.29 KXS09064.1 - 0.0018 18.7 0.0 0.0026 18.2 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KXS09064.1 - 0.0063 16.9 0.0 0.012 16.0 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain IPT PF01745.16 KXS09064.1 - 0.0072 15.7 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 Isopentenyl transferase dNK PF01712.19 KXS09064.1 - 0.018 14.9 0.0 0.043 13.7 0.0 1.6 2 0 0 2 2 2 0 Deoxynucleoside kinase AAA_22 PF13401.6 KXS09064.1 - 0.034 14.4 0.0 0.052 13.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 KXS09064.1 - 0.038 14.1 0.0 0.056 13.5 0.0 1.2 1 0 0 1 1 1 0 Dynamin family PduV-EutP PF10662.9 KXS09064.1 - 0.044 13.5 0.0 0.061 13.1 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 KXS09064.1 - 0.052 13.6 0.0 0.095 12.8 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase RNA_helicase PF00910.22 KXS09064.1 - 0.069 13.6 0.0 0.11 12.9 0.0 1.3 1 0 0 1 1 1 0 RNA helicase ATPase_2 PF01637.18 KXS09064.1 - 0.07 13.0 0.0 3.5 7.5 0.0 2.1 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea T2SSE PF00437.20 KXS09064.1 - 0.073 12.1 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_24 PF13479.6 KXS09064.1 - 0.074 12.8 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KXS09064.1 - 0.087 12.8 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) CobU PF02283.16 KXS09064.1 - 0.12 12.0 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase AAA_17 PF13207.6 KXS09064.1 - 0.14 12.6 0.0 0.49 10.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KXS09064.1 - 0.14 11.9 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain SnoaL_4 PF13577.6 KXS09065.1 - 0.028 14.6 0.1 0.031 14.4 0.1 1.2 1 0 0 1 1 1 0 SnoaL-like domain PBP1_TM PF14812.6 KXS09067.1 - 0.023 15.1 48.0 0.035 14.5 7.6 3.4 2 1 1 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PI3K_1B_p101 PF10486.9 KXS09067.1 - 0.97 7.1 8.9 0.033 12.0 2.5 1.6 2 0 0 2 2 2 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DUF4611 PF15387.6 KXS09067.1 - 1.5 9.1 35.5 0.056 13.7 2.7 3.5 3 1 0 3 3 3 0 Domain of unknown function (DUF4611) DNA_pol_phi PF04931.13 KXS09067.1 - 2.2 6.2 26.4 1.4 7.0 24.8 1.3 1 1 0 1 1 1 0 DNA polymerase phi PH_4 PF15404.6 KXS09067.1 - 4.7 7.0 6.0 0.72 9.6 1.1 1.9 2 0 0 2 2 2 0 Pleckstrin homology domain NOA36 PF06524.12 KXS09067.1 - 8 5.7 28.7 0.3 10.4 0.6 3.2 3 0 0 3 3 3 0 NOA36 protein CDC27 PF09507.10 KXS09067.1 - 9.6 5.5 36.5 0.6 9.4 17.6 2.0 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 zf-RING_2 PF13639.6 KXS09068.1 - 7.6e-11 42.2 5.0 1.2e-10 41.6 5.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KXS09068.1 - 3.3e-09 36.3 2.7 5.9e-09 35.5 2.7 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KXS09068.1 - 8.5e-09 35.1 5.7 1.3e-08 34.5 5.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXS09068.1 - 7.9e-08 32.0 4.3 1.2e-07 31.4 4.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KXS09068.1 - 3e-07 30.6 5.9 1.4e-06 28.5 5.9 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KXS09068.1 - 2.2e-05 24.4 1.1 3.7e-05 23.7 1.1 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 KXS09068.1 - 0.0002 21.3 2.1 0.00038 20.4 0.7 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 KXS09068.1 - 0.00031 20.6 2.4 0.00048 20.0 2.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KXS09068.1 - 0.00063 19.5 2.1 0.001 18.9 2.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.11 KXS09068.1 - 0.0096 16.2 1.6 0.015 15.6 1.6 1.3 1 0 0 1 1 1 1 RING-like domain PHD PF00628.29 KXS09068.1 - 0.013 15.4 3.1 0.013 15.4 3.1 1.9 2 0 0 2 2 2 0 PHD-finger Prok-RING_4 PF14447.6 KXS09068.1 - 0.022 14.6 4.8 0.042 13.7 4.8 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 KXS09068.1 - 0.064 12.9 2.8 0.12 12.0 2.8 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 KXS09068.1 - 0.7 9.7 3.5 1.3 8.9 3.5 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 KXS09068.1 - 0.84 9.9 4.6 9.9 6.4 4.6 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain Prok-RING_1 PF14446.6 KXS09068.1 - 1.3 9.0 3.7 3.2 7.8 1.0 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-C3H2C3 PF17122.5 KXS09068.1 - 2.4 8.2 6.2 5.7 7.1 6.2 1.7 1 1 0 1 1 1 0 Zinc-finger TPMT PF05724.11 KXS09069.1 - 2.3e-46 158.2 0.0 2.7e-46 158.0 0.0 1.0 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) DnaJ PF00226.31 KXS09070.1 - 4.7e-13 49.1 3.8 3e-12 46.5 0.1 3.0 3 0 0 3 3 3 1 DnaJ domain SPESP1 PF15754.5 KXS09070.1 - 0.091 11.9 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Sperm equatorial segment protein 1 ABA_WDS PF02496.16 KXS09071.1 - 0.00097 19.6 0.1 0.0013 19.1 0.1 1.2 1 0 0 1 1 1 1 ABA/WDS induced protein YadA_head PF05658.14 KXS09072.1 - 0.045 14.2 1.3 0.079 13.4 1.3 1.4 1 0 0 1 1 1 0 Head domain of trimeric autotransporter adhesin KxDL PF10241.9 KXS09073.1 - 0.0015 18.8 3.9 0.19 12.0 0.2 2.5 2 1 0 2 2 2 2 Uncharacterized conserved protein DUF4201 PF13870.6 KXS09073.1 - 0.0024 17.6 2.7 0.013 15.2 2.7 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4201) Vps54_N PF10475.9 KXS09073.1 - 0.0048 16.2 3.3 0.015 14.6 0.7 1.9 1 1 1 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex Lebercilin PF15619.6 KXS09073.1 - 0.0052 16.5 2.3 0.0052 16.5 2.3 1.9 1 1 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease DUF1664 PF07889.12 KXS09073.1 - 0.0078 16.2 4.1 0.024 14.6 1.9 1.9 1 1 1 2 2 2 2 Protein of unknown function (DUF1664) Effector_1 PF04518.12 KXS09073.1 - 0.0079 15.3 2.8 0.009 15.2 1.1 1.7 1 1 0 1 1 1 1 Effector from type III secretion system LXG PF04740.12 KXS09073.1 - 0.012 15.4 3.6 0.014 15.1 3.6 1.1 1 0 0 1 1 1 0 LXG domain of WXG superfamily YabA PF06156.13 KXS09073.1 - 0.028 15.0 2.0 0.2 12.3 0.4 2.1 1 1 1 2 2 2 0 Initiation control protein YabA HrpB7 PF09486.10 KXS09073.1 - 0.029 14.7 1.5 0.029 14.7 1.5 2.2 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) DUF3496 PF12001.8 KXS09073.1 - 0.037 14.4 1.6 0.64 10.4 0.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3496) Atg14 PF10186.9 KXS09073.1 - 0.062 12.4 8.3 0.076 12.1 8.3 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF2316 PF10078.9 KXS09073.1 - 0.09 13.0 1.4 0.21 11.8 1.3 1.8 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2316) Spc7 PF08317.11 KXS09073.1 - 0.12 11.2 7.3 0.26 10.1 7.3 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF4763 PF15960.5 KXS09073.1 - 0.15 11.3 6.1 0.2 10.9 6.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) TMF_TATA_bd PF12325.8 KXS09073.1 - 0.17 12.1 5.9 0.12 12.6 1.8 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF948 PF06103.11 KXS09073.1 - 0.17 12.2 2.1 3.2 8.1 0.1 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Seryl_tRNA_N PF02403.22 KXS09073.1 - 0.2 11.9 4.1 1.6 9.0 0.3 2.2 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain COG2 PF06148.11 KXS09073.1 - 0.24 11.5 2.5 0.84 9.7 0.3 2.1 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 TMPIT PF07851.13 KXS09073.1 - 0.28 10.4 2.6 0.34 10.1 2.6 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF1515 PF07439.11 KXS09073.1 - 0.31 11.1 6.5 3.2 7.8 0.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) DUF4200 PF13863.6 KXS09073.1 - 0.38 11.2 8.1 1.5 9.2 1.7 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) THOC7 PF05615.13 KXS09073.1 - 0.83 9.9 9.3 2.8 8.2 8.5 1.8 1 1 0 1 1 1 0 Tho complex subunit 7 DUF2721 PF11026.8 KXS09073.1 - 1 9.2 3.6 0.53 10.2 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) BST2 PF16716.5 KXS09073.1 - 1.1 9.9 7.0 0.64 10.6 3.6 2.0 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 ADIP PF11559.8 KXS09073.1 - 1.4 9.0 10.7 1.3 9.1 3.3 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding CorA PF01544.18 KXS09073.1 - 1.7 7.9 6.5 2.2 7.5 6.5 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DivIC PF04977.15 KXS09073.1 - 8.7 6.2 10.7 4 7.3 0.2 2.9 1 1 2 3 3 3 0 Septum formation initiator FUSC PF04632.12 KXS09073.1 - 9.6 4.6 11.7 11 4.4 11.7 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family GDP_Man_Dehyd PF16363.5 KXS09075.1 - 2.9e-54 184.7 0.0 3.8e-54 184.3 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KXS09075.1 - 1.3e-49 168.9 0.0 1.8e-49 168.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KXS09075.1 - 9.7e-16 57.7 0.0 5.4e-15 55.3 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 KXS09075.1 - 1.3e-15 57.2 0.0 8.9e-15 54.4 0.0 2.1 3 0 0 3 3 3 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KXS09075.1 - 1.7e-10 40.5 0.0 2.9e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 KXS09075.1 - 5.6e-06 25.7 0.0 0.011 14.9 0.0 2.6 2 1 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 KXS09075.1 - 1.9e-05 24.7 0.0 3.6e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 KXS09075.1 - 3.5e-05 23.8 0.0 5.9e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 KXS09075.1 - 0.00025 20.6 0.0 0.00049 19.6 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase Methyltransf_31 PF13847.6 KXS09075.1 - 0.045 13.5 0.0 0.11 12.2 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain NmrA PF05368.13 KXS09075.1 - 0.087 12.4 0.2 0.24 10.9 0.2 1.9 1 1 0 1 1 1 0 NmrA-like family TrkA_N PF02254.18 KXS09075.1 - 0.13 12.5 0.1 0.29 11.4 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain DAO PF01266.24 KXS09076.1 - 1.2e-27 97.5 4.8 2.8e-27 96.3 4.8 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXS09076.1 - 0.00033 20.0 0.0 0.0006 19.1 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXS09076.1 - 0.0015 19.1 0.0 0.0029 18.1 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXS09076.1 - 0.0056 16.9 0.7 0.016 15.5 0.7 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.18 KXS09076.1 - 0.0061 16.5 0.0 0.0094 15.8 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 KXS09076.1 - 0.019 14.5 0.3 0.037 13.6 0.3 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.19 KXS09076.1 - 0.023 14.1 0.0 0.04 13.3 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 KXS09076.1 - 0.025 13.8 0.0 0.039 13.2 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Glu_dehyd_C PF16912.5 KXS09076.1 - 0.035 13.6 0.1 0.11 12.0 0.0 1.8 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus NAD_binding_7 PF13241.6 KXS09076.1 - 0.058 13.8 0.0 0.1 13.1 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding ApbA PF02558.16 KXS09076.1 - 0.077 12.6 0.2 0.16 11.6 0.2 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA GDP_Man_Dehyd PF16363.5 KXS09077.1 - 9.5e-54 183.0 0.0 1.1e-53 182.8 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KXS09077.1 - 1.8e-50 171.7 0.0 2.1e-50 171.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXS09077.1 - 2.2e-16 59.7 0.0 2e-15 56.6 0.0 1.9 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KXS09077.1 - 3.6e-15 55.9 0.0 2.9e-14 52.9 0.0 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KXS09077.1 - 2.5e-10 39.9 0.0 3.8e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 KXS09077.1 - 7.2e-06 25.4 0.0 0.00056 19.2 0.0 2.5 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 KXS09077.1 - 1.3e-05 25.2 0.0 2.2e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 KXS09077.1 - 2.7e-05 24.2 0.1 4.2e-05 23.5 0.1 1.3 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 KXS09077.1 - 0.00028 20.4 0.0 0.00048 19.6 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase UDPG_MGDP_dh_N PF03721.14 KXS09077.1 - 0.052 13.1 0.1 0.084 12.4 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NmrA PF05368.13 KXS09077.1 - 0.056 13.0 0.1 0.18 11.3 0.1 1.8 2 0 0 2 2 2 0 NmrA-like family TrkA_N PF02254.18 KXS09077.1 - 0.18 12.1 0.1 0.33 11.2 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain Methyltransf_31 PF13847.6 KXS09077.1 - 0.19 11.5 0.0 0.45 10.3 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain Glyco_hydro_114 PF03537.13 KXS09078.1 - 5.9e-75 251.5 1.0 7.5e-75 251.2 1.0 1.0 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 Cation_ATPase_C PF00689.21 KXS09080.1 - 3.2e-38 131.3 4.9 3.2e-38 131.3 4.9 1.9 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KXS09080.1 - 1.5e-34 119.1 2.0 1.5e-34 119.1 2.0 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 KXS09080.1 - 7e-16 58.1 0.0 1.4e-15 57.1 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KXS09080.1 - 5.3e-15 56.3 12.8 1.1e-13 52.0 12.8 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KXS09080.1 - 5.9e-10 38.7 1.7 4.2e-09 36.0 0.0 2.7 3 0 0 3 3 3 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KXS09080.1 - 0.00033 20.5 0.9 0.0044 16.8 0.8 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase CPL PF08144.11 KXS09085.1 - 1.9e-12 47.7 0.0 1.6e-11 44.8 0.0 2.5 3 0 0 3 3 3 1 CPL (NUC119) domain PUF PF00806.19 KXS09085.1 - 0.00073 19.1 0.0 2.5 8.0 0.1 4.0 4 0 0 4 4 4 2 Pumilio-family RNA binding repeat YL1 PF05764.13 KXS09085.1 - 0.089 12.9 18.3 0.18 11.9 18.3 1.5 1 0 0 1 1 1 0 YL1 nuclear protein SDA1 PF05285.12 KXS09085.1 - 0.16 11.4 18.9 0.26 10.7 18.9 1.3 1 0 0 1 1 1 0 SDA1 LRR_4 PF12799.7 KXS09086.1 - 0.0076 16.6 4.1 0.11 13.0 0.0 2.4 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) Beta-lactamase PF00144.24 KXS09087.1 - 2.1e-21 76.5 0.7 5.7e-21 75.1 0.7 1.6 1 1 0 1 1 1 1 Beta-lactamase PDDEXK_1 PF12705.7 KXS09088.1 - 0.002 18.1 0.1 0.0048 16.8 0.0 1.7 2 0 0 2 2 2 1 PD-(D/E)XK nuclease superfamily Utp13 PF08625.11 KXS09088.1 - 0.076 12.9 0.1 0.78 9.6 0.0 2.5 3 0 0 3 3 3 0 Utp13 specific WD40 associated domain KicB PF03882.14 KXS09088.1 - 0.081 13.1 0.1 0.19 11.9 0.1 1.6 1 0 0 1 1 1 0 MukF winged-helix domain PhoLip_ATPase_N PF16209.5 KXS09089.1 - 3.5e-07 29.8 0.0 6.7e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cadherin_tail PF15974.5 KXS09089.1 - 0.07 13.5 0.9 0.11 12.9 0.2 1.8 2 0 0 2 2 2 0 Cadherin C-terminal cytoplasmic tail, catenin-binding region PorA PF11271.8 KXS09091.1 - 0.087 12.1 0.6 0.14 11.4 0.6 1.2 1 0 0 1 1 1 0 Porin PorA DUF1138 PF06592.13 KXS09093.1 - 0.18 11.9 0.1 0.38 10.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1138) Ank_2 PF12796.7 KXS09094.1 - 6.2e-20 71.6 1.1 2.9e-16 59.8 0.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXS09094.1 - 1.2e-14 54.4 0.8 1e-07 32.3 0.0 3.3 1 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXS09094.1 - 1.8e-14 52.4 0.8 7.6e-07 29.0 0.1 4.0 3 1 1 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 KXS09094.1 - 2.2e-13 50.2 1.3 7.3e-07 29.3 0.1 3.2 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 KXS09094.1 - 5.7e-11 42.3 5.2 1.2e-05 25.5 0.1 3.9 3 1 0 3 3 3 2 Ankyrin repeat DDE_Tnp_4 PF13359.6 KXS09095.1 - 1.9e-13 50.4 0.0 2.4e-13 50.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Feld-I_B PF09252.10 KXS09096.1 - 0.71 9.9 2.3 11 6.0 0.2 2.4 2 0 0 2 2 2 0 Allergen Fel d I-B chain Pacs-1 PF10254.9 KXS09096.1 - 2.2 7.2 6.0 4 6.3 4.7 1.8 1 1 1 2 2 2 0 PACS-1 cytosolic sorting protein Cu-oxidase PF00394.22 KXS09097.1 - 1.6e-40 138.8 0.2 2.1e-38 131.9 0.0 3.5 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 KXS09097.1 - 4.9e-37 126.6 9.8 6.6e-37 126.1 2.0 3.6 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KXS09097.1 - 6e-28 97.3 9.0 1.2e-24 86.6 0.4 4.3 3 2 0 3 3 3 2 Multicopper oxidase PAP2 PF01569.21 KXS09098.1 - 4.5e-27 94.5 1.4 4.5e-27 94.5 1.4 2.0 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 KXS09098.1 - 0.00095 18.9 13.5 0.038 13.7 0.6 3.3 3 0 0 3 3 3 2 PAP2 superfamily ECF_trnsprt PF12822.7 KXS09098.1 - 0.0013 18.9 1.0 0.7 10.0 0.2 2.3 2 0 0 2 2 2 2 ECF transporter, substrate-specific component SdpI PF13630.6 KXS09098.1 - 0.031 14.4 2.8 11 6.2 0.0 3.6 4 0 0 4 4 4 0 SdpI/YhfL protein family EamA PF00892.20 KXS09098.1 - 0.37 11.0 6.2 0.3 11.3 0.3 2.9 2 1 1 3 3 3 0 EamA-like transporter family Colicin_V PF02674.16 KXS09098.1 - 1.9 8.4 8.1 0.17 11.8 0.4 2.7 2 1 0 2 2 2 0 Colicin V production protein SUIM_assoc PF16619.5 KXS09101.1 - 0.038 14.0 1.7 0.074 13.1 1.7 1.5 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 GramPos_pilinD1 PF16555.5 KXS09104.1 - 1.8 8.7 12.1 0.33 11.1 8.0 1.7 2 0 0 2 2 2 0 Gram-positive pilin subunit D1, N-terminal domain AMP-binding PF00501.28 KXS09105.1 - 1.5e-97 326.9 0.0 1.8e-97 326.6 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXS09105.1 - 7e-17 62.2 0.3 7e-16 59.0 0.1 2.7 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain zf-RING_2 PF13639.6 KXS09107.1 - 3.2e-13 49.8 5.3 5.1e-13 49.1 5.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KXS09107.1 - 2e-11 43.4 2.5 4e-11 42.5 2.5 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KXS09107.1 - 2.4e-10 40.1 5.3 4.3e-10 39.3 5.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXS09107.1 - 7.9e-10 38.5 4.8 1.3e-09 37.8 4.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KXS09107.1 - 3.2e-09 36.9 3.0 6.6e-09 35.9 3.0 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KXS09107.1 - 2.4e-07 30.6 3.6 3.8e-07 29.9 3.6 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KXS09107.1 - 8.8e-06 25.7 4.4 1.8e-05 24.7 4.4 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KXS09107.1 - 0.00011 22.0 2.9 0.00017 21.4 2.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KXS09107.1 - 0.00049 19.9 3.5 0.00089 19.1 3.5 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KXS09107.1 - 0.00076 19.5 0.6 0.0013 18.7 0.6 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 KXS09107.1 - 0.012 15.3 4.6 0.049 13.3 5.0 1.7 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type RINGv PF12906.7 KXS09107.1 - 0.035 14.2 2.8 0.074 13.2 2.8 1.5 1 1 0 1 1 1 0 RING-variant domain zf-C3HC4_4 PF15227.6 KXS09107.1 - 0.055 13.6 2.7 0.16 12.2 2.7 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 KXS09107.1 - 0.37 11.0 5.4 1.5 9.0 5.4 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain Zf_RING PF16744.5 KXS09107.1 - 0.41 10.8 2.7 0.75 9.9 2.7 1.5 1 0 0 1 1 1 0 KIAA1045 RING finger zf-RING_4 PF14570.6 KXS09107.1 - 0.48 10.3 4.2 0.78 9.6 4.2 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.29 KXS09107.1 - 0.82 9.6 4.9 1.6 8.7 4.9 1.5 1 1 0 1 1 1 0 PHD-finger zf-RING-like PF08746.11 KXS09107.1 - 0.92 9.9 4.2 2.3 8.6 4.2 1.7 1 1 0 1 1 1 0 RING-like domain Ank PF00023.30 KXS09108.1 - 5.9e-06 26.5 0.2 0.31 11.6 0.0 4.0 4 1 0 4 4 3 2 Ankyrin repeat Ank_4 PF13637.6 KXS09108.1 - 4.2e-05 24.0 0.0 0.12 13.0 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXS09108.1 - 0.00012 22.2 0.0 0.67 10.7 0.0 3.7 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.7 KXS09108.1 - 0.00065 20.2 0.0 0.12 13.0 0.1 3.0 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) SH3_9 PF14604.6 KXS09108.1 - 0.0019 18.0 0.3 0.0045 16.8 0.0 1.7 2 0 0 2 2 2 1 Variant SH3 domain bZIP_1 PF00170.21 KXS09108.1 - 0.0069 16.5 0.3 0.014 15.5 0.3 1.5 1 0 0 1 1 1 1 bZIP transcription factor Ank_5 PF13857.6 KXS09108.1 - 0.013 15.8 0.0 9.5 6.7 0.0 3.4 3 0 0 3 3 3 0 Ankyrin repeats (many copies) SH3_1 PF00018.28 KXS09108.1 - 0.035 13.7 0.3 0.097 12.3 0.0 1.8 2 0 0 2 2 2 0 SH3 domain APG6_N PF17675.1 KXS09108.1 - 0.042 14.4 0.0 0.07 13.7 0.0 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region YabA PF06156.13 KXS09108.1 - 0.045 14.4 0.4 0.08 13.6 0.4 1.4 1 0 0 1 1 1 0 Initiation control protein YabA ATG16 PF08614.11 KXS09108.1 - 0.063 13.5 0.4 0.12 12.6 0.4 1.6 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Agglutinin_C PF18021.1 KXS09108.1 - 0.13 12.7 0.0 0.44 11.1 0.0 1.8 2 0 0 2 2 2 0 Agglutinin C-terminal ZapB PF06005.12 KXS09108.1 - 0.41 11.1 4.4 1.4 9.5 0.8 2.3 1 1 1 2 2 2 0 Cell division protein ZapB Shugoshin_N PF07558.11 KXS09108.1 - 0.63 10.0 5.1 1.5 8.8 3.6 2.4 2 1 0 2 2 2 0 Shugoshin N-terminal coiled-coil region Phage_holin_3_6 PF07332.11 KXS09109.1 - 0.35 10.9 12.2 0.86 9.7 0.2 2.6 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III DNA_pol_phi PF04931.13 KXS09112.1 - 3.4 5.7 6.4 4.4 5.3 6.4 1.2 1 0 0 1 1 1 0 DNA polymerase phi Cwf_Cwc_15 PF04889.12 KXS09112.1 - 3.6 7.2 8.5 5.9 6.6 8.5 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein p450 PF00067.22 KXS09113.1 - 3.7e-34 118.3 0.0 3.1e-31 108.6 0.0 3.1 2 2 1 3 3 3 1 Cytochrome P450 Peptidase_C12 PF01088.21 KXS09114.1 - 2.2e-50 171.3 0.0 6.2e-50 169.9 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 KXS09114.1 - 9.8e-09 35.0 0.5 4.7e-08 32.8 0.2 2.3 1 1 1 2 2 2 1 Ubiquitin carboxyl-terminal hydrolases Atg14 PF10186.9 KXS09114.1 - 0.099 11.7 4.0 0.19 10.8 4.0 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 CAMSAP_CC1 PF17095.5 KXS09114.1 - 0.89 9.4 6.4 3.1 7.7 0.1 2.6 2 0 0 2 2 2 0 Spectrin-binding region of Ca2+-Calmodulin ASXH PF13919.6 KXS09114.1 - 8.9 6.3 11.7 0.088 12.8 2.1 2.5 3 0 0 3 3 3 0 Asx homology domain adh_short PF00106.25 KXS09117.1 - 3.6e-47 160.3 0.1 4.9e-47 159.9 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXS09117.1 - 2.6e-38 131.9 0.1 3.3e-38 131.5 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXS09117.1 - 6.9e-08 32.6 0.1 1.3e-07 31.7 0.1 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KXS09117.1 - 0.002 17.7 0.2 0.0083 15.6 0.1 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family HI0933_like PF03486.14 KXS09117.1 - 0.029 13.1 0.4 0.046 12.4 0.4 1.3 1 0 0 1 1 1 0 HI0933-like protein F420_oxidored PF03807.17 KXS09117.1 - 0.043 14.4 0.0 0.093 13.3 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent GDP_Man_Dehyd PF16363.5 KXS09117.1 - 0.061 12.7 0.3 0.2 11.0 0.0 1.8 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase HGTP_anticodon PF03129.20 KXS09117.1 - 0.094 12.9 0.0 11 6.2 0.0 2.3 2 0 0 2 2 2 0 Anticodon binding domain Peptidase_C11 PF03415.14 KXS09117.1 - 0.17 11.2 0.0 0.22 10.9 0.0 1.1 1 0 0 1 1 1 0 Clostripain family PQQ_2 PF13360.6 KXS09118.1 - 3.2e-11 43.3 0.1 1.4e-09 37.9 0.1 2.1 1 1 0 1 1 1 1 PQQ-like domain PQQ PF01011.21 KXS09118.1 - 2.1e-08 33.7 0.5 0.2 11.7 0.1 3.3 3 0 0 3 3 3 3 PQQ enzyme repeat PQQ_3 PF13570.6 KXS09118.1 - 4e-05 24.0 3.3 0.005 17.3 0.2 3.3 2 1 1 3 3 3 1 PQQ-like domain Ank_3 PF13606.6 KXS09119.1 - 6.9e-12 44.5 7.8 0.046 14.3 0.0 7.7 8 0 0 8 8 8 3 Ankyrin repeat Ank_2 PF12796.7 KXS09119.1 - 4.5e-10 40.0 3.9 0.0057 17.2 0.0 6.7 6 3 1 7 7 7 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXS09119.1 - 1.3e-08 35.2 0.4 0.53 10.9 0.0 6.8 8 0 0 8 8 8 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXS09119.1 - 5e-07 29.9 1.5 0.0036 17.6 0.0 5.3 5 1 0 5 5 5 1 Ankyrin repeats (many copies) Ank PF00023.30 KXS09119.1 - 1.2e-06 28.7 8.3 1.1 9.8 0.0 7.3 8 0 0 8 8 8 2 Ankyrin repeat SH3_9 PF14604.6 KXS09120.1 - 7.2e-12 45.0 0.0 1.1e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXS09120.1 - 3.7e-10 39.3 0.0 6.1e-10 38.5 0.0 1.4 1 0 0 1 1 1 1 SH3 domain ATG16 PF08614.11 KXS09120.1 - 0.0018 18.5 3.2 0.0025 18.1 3.2 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.9 KXS09120.1 - 0.0029 17.7 3.6 0.0045 17.0 3.6 1.3 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SH3_2 PF07653.17 KXS09120.1 - 0.0088 15.7 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain Med9 PF07544.13 KXS09120.1 - 0.01 15.9 5.7 0.017 15.2 5.7 1.3 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Phage_GP20 PF06810.11 KXS09120.1 - 0.012 15.5 1.3 0.017 14.9 1.3 1.3 1 0 0 1 1 1 0 Phage minor structural protein GP20 Tropomyosin_1 PF12718.7 KXS09120.1 - 0.014 15.5 6.0 0.02 15.0 6.0 1.1 1 0 0 1 1 1 0 Tropomyosin like UPF0242 PF06785.11 KXS09120.1 - 0.017 15.2 1.9 0.023 14.8 1.9 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Uso1_p115_C PF04871.13 KXS09120.1 - 0.025 15.0 7.1 0.034 14.5 7.1 1.2 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Atg14 PF10186.9 KXS09120.1 - 0.03 13.4 1.6 0.036 13.2 1.6 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Spc7 PF08317.11 KXS09120.1 - 0.034 13.0 4.2 0.041 12.8 4.2 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein GAS PF13851.6 KXS09120.1 - 0.036 13.4 4.2 0.05 12.9 4.2 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding TPR_MLP1_2 PF07926.12 KXS09120.1 - 0.036 14.1 9.4 0.76 9.8 2.7 2.1 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein TMF_TATA_bd PF12325.8 KXS09120.1 - 0.039 14.2 4.9 0.052 13.8 4.9 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding TMCO5 PF14992.6 KXS09120.1 - 0.047 13.3 2.1 0.056 13.0 2.1 1.1 1 0 0 1 1 1 0 TMCO5 family Phage_GPO PF05929.11 KXS09120.1 - 0.067 12.8 1.1 0.09 12.4 1.1 1.1 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DivIC PF04977.15 KXS09120.1 - 0.083 12.7 6.6 0.06 13.1 4.5 1.8 1 1 1 2 2 2 0 Septum formation initiator Seryl_tRNA_N PF02403.22 KXS09120.1 - 0.11 12.8 4.1 0.15 12.3 4.1 1.2 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain FapA PF03961.13 KXS09120.1 - 0.12 10.9 0.8 0.14 10.7 0.8 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A FemAB PF02388.16 KXS09120.1 - 0.15 10.9 1.9 0.18 10.6 1.9 1.1 1 0 0 1 1 1 0 FemAB family DUF4763 PF15960.5 KXS09120.1 - 0.19 11.0 3.3 0.32 10.3 3.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4763) Cauli_AT PF03233.13 KXS09120.1 - 0.2 11.6 2.7 0.3 11.0 2.7 1.2 1 0 0 1 1 1 0 Aphid transmission protein Golgin_A5 PF09787.9 KXS09120.1 - 0.21 11.0 6.1 0.84 9.0 5.9 1.6 1 1 0 1 1 1 0 Golgin subfamily A member 5 HAUS-augmin3 PF14932.6 KXS09120.1 - 0.23 11.0 4.8 0.32 10.5 4.8 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 ABC_tran_CTD PF16326.5 KXS09120.1 - 0.27 11.5 9.5 0.11 12.7 4.0 2.3 1 1 1 2 2 2 0 ABC transporter C-terminal domain Lectin_N PF03954.14 KXS09120.1 - 0.5 10.1 4.1 0.36 10.6 1.6 1.9 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain ADIP PF11559.8 KXS09120.1 - 0.61 10.2 7.2 1.3 9.1 7.3 1.5 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding Sipho_Gp157 PF05565.11 KXS09120.1 - 0.74 9.8 6.0 0.49 10.4 1.1 2.0 1 1 1 2 2 2 0 Siphovirus Gp157 TMF_DNA_bd PF12329.8 KXS09120.1 - 0.81 9.7 11.5 0.41 10.7 6.1 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding JIP_LZII PF16471.5 KXS09120.1 - 0.81 9.9 5.5 0.16 12.1 1.3 1.8 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II Spc24 PF08286.11 KXS09120.1 - 1.3 9.3 5.0 3.7 7.8 4.9 1.8 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 Prefoldin_2 PF01920.20 KXS09120.1 - 1.4 8.9 7.4 0.93 9.5 2.3 2.2 1 1 1 2 2 2 0 Prefoldin subunit FlaC_arch PF05377.11 KXS09120.1 - 1.8 9.0 4.3 5.8 7.4 1.4 2.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Ank_3 PF13606.6 KXS09121.1 - 0.001 19.4 0.0 0.0095 16.4 0.0 2.5 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 KXS09121.1 - 0.034 14.5 0.0 0.38 11.1 0.0 2.6 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXS09121.1 - 0.17 12.5 0.0 0.66 10.6 0.0 1.9 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXS09123.1 - 2.5e-06 27.6 0.3 0.15 12.4 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXS09123.1 - 0.00013 22.5 0.0 0.00033 21.2 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) SH3_9 PF14604.6 KXS09123.1 - 0.00025 20.9 0.1 0.0005 19.9 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain Ank_3 PF13606.6 KXS09123.1 - 0.0036 17.7 0.2 0.094 13.3 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 KXS09123.1 - 0.0052 17.3 0.1 0.4 11.3 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeats (many copies) HalX PF08663.10 KXS09123.1 - 0.042 14.2 0.2 0.084 13.2 0.2 1.4 1 0 0 1 1 1 0 HalX domain Ank PF00023.30 KXS09123.1 - 0.16 12.4 0.0 0.67 10.5 0.0 2.1 1 0 0 1 1 1 0 Ankyrin repeat Abhydrolase_1 PF00561.20 KXS09124.1 - 4.5e-11 42.9 0.0 4.2e-10 39.7 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXS09124.1 - 1.6e-09 38.7 0.0 2.3e-09 38.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXS09124.1 - 2.7e-07 30.1 0.0 1.8e-06 27.4 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DUF4570 PF15134.6 KXS09124.1 - 0.046 13.7 0.1 0.096 12.7 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4570) SH3_9 PF14604.6 KXS09125.1 - 3.2e-07 30.1 0.0 6.6e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXS09125.1 - 2.8e-06 26.8 0.1 4.8e-06 26.1 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KXS09125.1 - 0.00049 19.7 0.0 0.001 18.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Ank_2 PF12796.7 KXS09125.1 - 0.00085 19.9 0.0 0.0017 18.9 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXS09125.1 - 0.0075 16.7 0.0 0.12 13.0 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeat Glyco_hydro_18 PF00704.28 KXS09129.1 - 1.4e-49 169.5 0.2 1.7e-49 169.2 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Cullin PF00888.22 KXS09130.1 - 0.092 11.3 0.0 0.1 11.2 0.0 1.0 1 0 0 1 1 1 0 Cullin family adh_short PF00106.25 KXS09131.1 - 6.1e-26 91.1 0.3 1.2e-25 90.2 0.2 1.4 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXS09131.1 - 7.4e-19 68.2 0.5 1e-18 67.7 0.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXS09131.1 - 1.3e-06 28.4 0.0 2e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KXS09131.1 - 1.1e-05 25.4 0.4 2.8e-05 24.1 0.2 1.7 2 0 0 2 2 2 1 NAD(P)H-binding Hyaluronidase_1 PF07212.11 KXS09131.1 - 0.072 12.4 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Hyaluronidase protein (HylP) BSP_II PF05432.11 KXS09132.1 - 0.14 11.9 1.3 0.2 11.4 1.3 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) zf-C3HC4_2 PF13923.6 KXS09133.1 - 1.9e-11 43.6 7.1 2.4e-11 43.3 7.1 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXS09133.1 - 1.7e-10 41.0 7.4 2.1e-10 40.8 7.4 1.1 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KXS09133.1 - 7.2e-09 35.4 5.9 9.1e-09 35.0 5.9 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXS09133.1 - 2.9e-07 30.4 2.2 4.3e-07 29.8 2.2 1.2 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KXS09133.1 - 7.3e-07 28.9 3.9 8.3e-07 28.8 3.9 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KXS09133.1 - 1.4e-06 28.5 9.7 4.6e-06 26.8 9.7 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 KXS09133.1 - 5.9e-06 25.9 1.7 1.4e-05 24.7 1.7 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_5 PF14634.6 KXS09133.1 - 2.1e-05 24.4 4.8 2.6e-05 24.1 4.8 1.2 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3H2C3 PF17122.5 KXS09133.1 - 0.00053 20.0 4.7 0.0011 18.9 4.7 1.5 1 1 0 1 1 1 1 Zinc-finger Zn_ribbon_17 PF17120.5 KXS09133.1 - 0.0062 16.1 6.7 0.0093 15.6 6.7 1.4 1 1 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 KXS09133.1 - 0.0094 16.0 5.9 0.019 15.0 5.9 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 KXS09133.1 - 0.012 15.3 5.0 0.023 14.5 5.0 1.4 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 KXS09133.1 - 0.015 15.4 2.6 0.028 14.6 2.6 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING-like PF08746.11 KXS09133.1 - 0.16 12.3 9.5 0.34 11.2 9.5 1.6 1 1 0 1 1 1 0 RING-like domain Baculo_RING PF05883.11 KXS09133.1 - 0.18 11.8 2.4 0.65 10.0 2.4 1.8 1 1 0 1 1 1 0 Baculovirus U-box/Ring-like domain LRR_8 PF13855.6 KXS09134.1 - 4e-07 29.7 2.9 0.00011 21.9 0.2 3.2 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 KXS09134.1 - 0.00033 21.0 4.1 0.74 10.3 0.5 3.8 2 1 3 5 5 5 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KXS09134.1 - 0.0082 16.5 3.8 69 4.6 0.0 4.7 3 1 0 3 3 3 0 Leucine Rich Repeat Ank PF00023.30 KXS09136.1 - 2.2e-06 27.8 1.7 0.14 12.6 0.1 3.6 3 1 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 KXS09136.1 - 1.3e-05 25.2 0.2 0.011 16.2 0.1 3.5 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.7 KXS09136.1 - 0.00011 22.8 0.2 0.045 14.3 0.1 3.0 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXS09136.1 - 0.00064 20.0 0.5 0.049 14.0 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXS09136.1 - 0.012 16.1 0.2 5.6 7.7 0.1 2.7 2 1 1 3 3 3 0 Ankyrin repeats (many copies) Cation_ATPase_C PF00689.21 KXS09138.1 - 3.9e-32 111.4 2.4 3.9e-32 111.4 2.4 1.8 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KXS09138.1 - 8.6e-18 64.5 3.9 8.8e-18 64.5 0.4 2.6 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 KXS09138.1 - 2e-13 50.2 0.0 1.4e-12 47.5 0.0 2.2 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KXS09138.1 - 3.7e-12 47.0 3.3 1.4e-11 45.1 3.3 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KXS09138.1 - 1.5e-06 28.2 1.0 0.00026 20.8 0.3 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase MerC PF03203.14 KXS09138.1 - 3.8 8.0 7.1 3.6 8.1 1.3 2.8 2 1 0 2 2 2 0 MerC mercury resistance protein E1-E2_ATPase PF00122.20 KXS09139.1 - 0.12 11.9 1.2 0.29 10.6 1.1 1.9 1 1 0 1 1 1 0 E1-E2 ATPase zf-C3HC4_2 PF13923.6 KXS09140.1 - 0.00069 19.4 10.4 0.0015 18.3 10.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXS09140.1 - 0.00098 19.1 11.6 0.0022 18.0 11.6 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KXS09140.1 - 0.001 18.9 9.9 0.0021 17.9 9.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXS09140.1 - 0.0012 19.1 10.3 0.0012 19.1 10.3 1.6 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 KXS09140.1 - 0.029 14.7 10.5 0.096 13.0 10.5 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger domain Sina PF03145.16 KXS09140.1 - 0.047 13.6 0.1 0.074 13.0 0.1 1.2 1 0 0 1 1 1 0 Seven in absentia protein family zf-C3HC4_3 PF13920.6 KXS09140.1 - 0.39 10.6 9.0 0.86 9.5 9.0 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Serpin PF00079.20 KXS09142.1 - 1.1e-31 110.5 0.0 3.6e-21 75.9 0.0 2.0 2 0 0 2 2 2 2 Serpin (serine protease inhibitor) Met_10 PF02475.16 KXS09143.1 - 0.059 13.1 0.1 0.09 12.5 0.1 1.2 1 0 0 1 1 1 0 Met-10+ like-protein STE2 PF02116.15 KXS09144.1 - 0.094 12.0 12.0 0.12 11.7 9.5 2.3 1 1 1 2 2 2 0 Fungal pheromone mating factor STE2 GPCR ArgoMid PF16487.5 KXS09144.1 - 0.15 12.3 0.0 0.25 11.6 0.0 1.3 1 0 0 1 1 1 0 Mid domain of argonaute Methyltransf_31 PF13847.6 KXS09146.1 - 6.1e-15 55.3 0.0 2.1e-14 53.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXS09146.1 - 2.1e-13 50.8 0.0 5e-13 49.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXS09146.1 - 1.2e-11 44.7 0.0 1.8e-11 44.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXS09146.1 - 1.8e-11 44.5 0.0 1.9e-10 41.2 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXS09146.1 - 6.4e-11 42.9 0.0 1.1e-10 42.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 KXS09146.1 - 5.9e-05 22.8 0.0 8.9e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) MTS PF05175.14 KXS09146.1 - 0.002 17.7 0.0 0.0044 16.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 KXS09146.1 - 0.045 13.1 0.0 0.064 12.6 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 KXS09146.1 - 0.1 12.6 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain AdoHcyase_NAD PF00670.21 KXS09146.1 - 0.12 12.5 0.0 0.36 10.9 0.0 1.7 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Methyltransf_4 PF02390.17 KXS09146.1 - 0.22 11.0 0.0 0.35 10.3 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase CMAS PF02353.20 KXS09146.1 - 0.24 10.7 0.0 0.36 10.1 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase AAA PF00004.29 KXS09147.1 - 9.5e-17 61.7 0.0 2e-16 60.6 0.0 1.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KXS09147.1 - 0.00022 21.5 0.1 0.024 14.9 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 KXS09147.1 - 0.00065 20.1 0.4 0.0024 18.3 0.4 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_2 PF07724.14 KXS09147.1 - 0.003 17.7 0.0 0.01 16.0 0.0 2.1 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 KXS09147.1 - 0.0031 17.5 0.0 0.0073 16.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Zot PF05707.12 KXS09147.1 - 0.033 13.8 0.0 2.4 7.8 0.0 2.3 1 1 1 2 2 2 0 Zonular occludens toxin (Zot) Mg_chelatase PF01078.21 KXS09147.1 - 0.035 13.5 0.6 0.15 11.5 0.1 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI CPT PF07931.12 KXS09147.1 - 0.047 13.5 0.1 0.95 9.3 0.0 2.3 1 1 1 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_19 PF13245.6 KXS09147.1 - 0.067 13.5 1.5 0.99 9.7 1.5 2.2 1 1 0 1 1 1 0 AAA domain RuvB_N PF05496.12 KXS09147.1 - 0.13 12.0 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Vps36_ESCRT-II PF11605.8 KXS09147.1 - 0.15 12.2 0.0 0.33 11.2 0.0 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 DsrC PF04358.13 KXS09147.1 - 0.16 12.5 0.0 0.29 11.7 0.0 1.4 1 0 0 1 1 1 0 DsrC like protein FAD_binding_4 PF01565.23 KXS09148.1 - 3.5e-16 59.2 0.0 5.6e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain GalKase_gal_bdg PF10509.9 KXS09149.1 - 1.3e-15 56.7 0.6 1.1e-14 53.7 0.6 2.4 1 1 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.13 KXS09149.1 - 1.3e-12 47.8 0.0 3e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 KXS09149.1 - 1.1e-09 38.4 2.5 2.7e-09 37.1 2.5 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain 7tm_3 PF00003.22 KXS09150.1 - 1.7e-26 93.4 15.2 2.4e-26 93.0 15.2 1.1 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR LANC_like PF05147.13 KXS09152.1 - 1.6e-19 69.7 0.0 4.2e-14 51.9 0.0 2.1 2 0 0 2 2 2 2 Lanthionine synthetase C-like protein Methyltransf_11 PF08241.12 KXS09153.1 - 2.6e-05 24.8 0.1 9.4e-05 23.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Glyco_trans_2_3 PF13632.6 KXS09153.1 - 0.0027 17.7 0.0 0.0047 16.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Methyltransf_25 PF13649.6 KXS09153.1 - 0.027 15.2 0.0 0.18 12.5 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain AdoMet_MTase PF07757.13 KXS09154.1 - 8.8e-29 100.1 0.0 1.6e-28 99.2 0.0 1.4 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_31 PF13847.6 KXS09154.1 - 0.0099 15.7 0.0 0.016 15.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXS09154.1 - 0.046 14.4 0.0 0.1 13.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.6 KXS09154.1 - 0.1 12.6 0.2 0.73 9.8 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Pkinase PF00069.25 KXS09155.1 - 2e-24 86.4 0.0 1.5e-12 47.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXS09155.1 - 2e-05 24.0 0.1 0.00035 20.0 0.0 2.2 2 1 0 2 2 2 1 Protein tyrosine kinase Aldolase_II PF00596.21 KXS09156.1 - 8.5e-28 97.6 0.0 1.3e-27 97.0 0.0 1.3 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain HTH_5 PF01022.20 KXS09156.1 - 0.16 11.8 0.0 0.26 11.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family FAD_binding_4 PF01565.23 KXS09157.1 - 2.8e-26 91.9 1.2 6.2e-26 90.8 1.2 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXS09157.1 - 9.2e-10 38.5 0.0 1.7e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 Berberine and berberine like Peptidase_M30 PF10460.9 KXS09157.1 - 0.055 12.4 0.0 0.08 11.9 0.0 1.2 1 0 0 1 1 1 0 Peptidase M30 Glyoxalase PF00903.25 KXS09159.1 - 0.0023 18.1 0.0 0.0029 17.8 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily FAA_hydrolase PF01557.18 KXS09160.1 - 1.6e-62 211.0 0.0 2.2e-62 210.6 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family AOC_like PF18678.1 KXS09160.1 - 0.027 14.1 0.0 0.13 11.8 0.0 2.0 2 0 0 2 2 2 0 Allene oxide cyclase barrel like domain Zn_clus PF00172.18 KXS09161.1 - 4e-08 33.2 9.0 6.6e-08 32.6 9.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyoxalase PF00903.25 KXS09162.1 - 3.8e-11 43.3 0.1 5.5e-11 42.8 0.1 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 KXS09162.1 - 6.1e-05 23.8 0.0 0.00011 22.9 0.0 1.4 1 0 0 1 1 1 1 Glyoxalase-like domain CppA_N PF14506.6 KXS09162.1 - 0.032 14.3 0.0 0.049 13.7 0.0 1.3 1 0 0 1 1 1 0 CppA N-terminal FAD_binding_3 PF01494.19 KXS09163.1 - 5.7e-43 147.5 0.0 9.5e-29 100.7 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 KXS09163.1 - 0.00091 18.5 0.0 0.0035 16.6 0.0 1.9 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 KXS09163.1 - 0.0029 17.8 0.0 0.0055 16.9 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain 3HCDH_N PF02737.18 KXS09163.1 - 0.0059 16.5 0.0 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 KXS09163.1 - 0.012 14.7 0.1 0.026 13.6 0.0 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein F420_oxidored PF03807.17 KXS09163.1 - 0.013 16.1 0.1 0.085 13.4 0.0 2.3 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_8 PF13450.6 KXS09163.1 - 0.021 15.0 0.1 0.098 12.9 0.0 2.2 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KXS09163.1 - 0.026 13.8 0.0 0.044 13.0 0.0 1.2 1 0 0 1 1 1 0 Thi4 family ApbA PF02558.16 KXS09163.1 - 0.064 12.9 0.0 0.36 10.5 0.0 2.0 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.23 KXS09163.1 - 0.11 12.5 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus HI0933_like PF03486.14 KXS09163.1 - 0.2 10.3 0.0 0.28 9.9 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein EI24 PF07264.11 KXS09165.1 - 2.8e-11 44.0 16.6 3.6e-11 43.6 16.6 1.1 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) ABC_membrane_2 PF06472.15 KXS09166.1 - 2.5e-47 161.6 1.4 5.6e-47 160.4 1.4 1.5 1 1 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 KXS09166.1 - 9.6e-12 45.6 0.0 2.4e-11 44.3 0.0 1.7 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KXS09166.1 - 0.00099 19.0 0.1 0.0021 17.9 0.1 1.5 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system DUF3584 PF12128.8 KXS09166.1 - 0.0098 13.5 0.2 0.013 13.0 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) AAA_30 PF13604.6 KXS09166.1 - 0.026 14.2 0.1 0.047 13.4 0.1 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KXS09166.1 - 0.042 13.8 0.2 0.075 12.9 0.2 1.4 1 0 0 1 1 1 0 NACHT domain AAA_29 PF13555.6 KXS09166.1 - 0.057 13.2 0.1 0.12 12.2 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 KXS09166.1 - 0.11 13.0 0.0 0.18 12.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 KXS09166.1 - 0.32 10.7 0.0 0.75 9.4 0.0 1.5 2 0 0 2 2 2 0 AAA ATPase domain Methyltransf_21 PF05050.12 KXS09167.1 - 3.6e-09 36.9 0.0 8.4e-08 32.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase FkbM domain Kinesin PF00225.23 KXS09168.1 - 3.2e-119 397.8 0.7 4.9e-119 397.2 0.7 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KXS09168.1 - 9.7e-25 87.2 0.0 2.3e-24 86.0 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding DUF812 PF05667.11 KXS09168.1 - 0.00012 21.1 11.3 0.00015 20.8 11.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Homeodomain PF00046.29 KXS09168.1 - 0.0083 16.0 0.7 0.025 14.4 0.7 1.8 1 0 0 1 1 1 1 Homeodomain PIF1 PF05970.14 KXS09168.1 - 0.018 14.2 0.2 0.036 13.2 0.2 1.4 1 0 0 1 1 1 0 PIF1-like helicase DinB_2 PF12867.7 KXS09168.1 - 0.021 15.3 0.3 0.056 14.0 0.3 1.8 1 0 0 1 1 1 0 DinB superfamily MHC_I_3 PF16497.5 KXS09168.1 - 0.069 12.6 0.1 0.12 11.8 0.1 1.3 1 0 0 1 1 1 0 MHC-I family domain Atg14 PF10186.9 KXS09168.1 - 0.071 12.2 9.8 0.14 11.3 9.8 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF948 PF06103.11 KXS09168.1 - 0.095 13.0 3.3 0.12 12.7 1.0 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) AAA_16 PF13191.6 KXS09168.1 - 0.14 12.5 0.0 0.14 12.5 0.0 2.7 2 1 0 2 2 1 0 AAA ATPase domain AAA_22 PF13401.6 KXS09168.1 - 0.22 11.8 0.1 0.22 11.8 0.1 2.8 3 1 0 3 3 3 0 AAA domain Lectin_N PF03954.14 KXS09168.1 - 0.45 10.3 3.5 1.7 8.4 3.5 2.0 1 1 0 1 1 1 0 Hepatic lectin, N-terminal domain DUF724 PF05266.14 KXS09168.1 - 3.7 7.4 14.4 2.6 7.8 11.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Kinesin_assoc PF16183.5 KXS09168.1 - 8.9 6.4 15.7 91 3.1 12.8 2.8 2 1 0 2 2 2 0 Kinesin-associated p450 PF00067.22 KXS09169.1 - 4.9e-08 32.2 0.6 2.5e-07 29.8 0.9 1.7 1 1 1 2 2 2 1 Cytochrome P450 MotA_ExbB PF01618.16 KXS09169.1 - 0.11 12.2 0.5 0.26 11.0 0.2 1.7 2 0 0 2 2 2 0 MotA/TolQ/ExbB proton channel family DHHC PF01529.20 KXS09170.1 - 1.8e-35 122.0 7.1 3.3e-35 121.1 7.1 1.4 1 0 0 1 1 1 1 DHHC palmitoyltransferase Cut8 PF08559.10 KXS09171.1 - 1.1e-35 123.3 0.0 2.1e-35 122.5 0.0 1.4 1 1 0 1 1 1 1 Cut8, nuclear proteasome tether protein DnaJ PF00226.31 KXS09172.1 - 1e-19 70.4 0.8 1.4e-18 66.8 0.1 2.8 2 0 0 2 2 2 1 DnaJ domain Myb_DNA-binding PF00249.31 KXS09172.1 - 1.1e-07 31.9 0.2 0.012 15.8 0.1 3.0 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KXS09172.1 - 0.0018 18.5 2.9 0.95 9.8 0.0 3.1 3 0 0 3 3 3 2 Myb-like DNA-binding domain adh_short PF00106.25 KXS09173.1 - 5.2e-34 117.4 0.1 6.7e-34 117.0 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXS09173.1 - 2.5e-25 89.4 0.0 2.8e-25 89.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXS09173.1 - 0.00032 20.7 0.0 0.00057 19.8 0.0 1.4 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KXS09173.1 - 0.0017 18.3 0.1 0.0024 17.8 0.1 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.21 KXS09173.1 - 0.076 12.5 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family ApbA PF02558.16 KXS09173.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.23 KXS09173.1 - 0.11 12.4 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox PF00070.27 KXS09173.1 - 0.18 12.4 0.1 0.36 11.4 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AMP-binding PF00501.28 KXS09174.1 - 6.7e-91 305.0 0.0 8.3e-91 304.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXS09174.1 - 4e-16 59.8 1.3 9.7e-16 58.5 1.3 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain LRR_4 PF12799.7 KXS09176.1 - 2.3e-15 56.4 19.1 3.8e-06 27.1 2.6 5.6 3 1 0 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXS09176.1 - 5e-15 55.0 18.3 2.6e-08 33.5 6.9 4.3 2 1 2 4 4 4 4 Leucine rich repeat SH3_1 PF00018.28 KXS09176.1 - 4.1e-05 23.1 0.0 8.8e-05 22.0 0.0 1.5 1 0 0 1 1 1 1 SH3 domain LRR_1 PF00560.33 KXS09176.1 - 0.0097 16.3 18.7 41 5.3 0.0 8.0 8 1 0 8 8 8 0 Leucine Rich Repeat SH3_9 PF14604.6 KXS09176.1 - 0.01 15.7 0.0 0.024 14.5 0.0 1.6 1 0 0 1 1 1 0 Variant SH3 domain LRR_5 PF13306.6 KXS09176.1 - 0.065 13.2 0.1 0.37 10.7 0.2 2.2 2 0 0 2 2 2 0 BspA type Leucine rich repeat region (6 copies) MGC-24 PF05283.11 KXS09176.1 - 0.53 10.7 3.6 0.16 12.4 0.3 1.8 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin EBP PF05241.12 KXS09177.1 - 1.9e-54 183.8 9.6 2.2e-54 183.6 9.6 1.0 1 0 0 1 1 1 1 Emopamil binding protein Med10 PF09748.9 KXS09178.1 - 4.8e-25 87.9 0.7 5.5e-25 87.7 0.7 1.0 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex ACT_5 PF13710.6 KXS09178.1 - 0.017 15.0 0.2 0.031 14.1 0.2 1.4 1 0 0 1 1 1 0 ACT domain DUF3634 PF12321.8 KXS09178.1 - 0.072 13.5 0.1 0.22 11.9 0.1 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3634) SDA1 PF05285.12 KXS09179.1 - 2.6e-40 138.9 56.0 5.1e-38 131.4 24.0 3.2 2 1 1 3 3 3 2 SDA1 NUC130_3NT PF08158.12 KXS09179.1 - 3.8e-26 91.2 0.5 1.6e-25 89.1 0.5 2.2 1 0 0 1 1 1 1 NUC130/3NT domain Cnd1 PF12717.7 KXS09179.1 - 0.52 10.3 4.0 0.65 10.0 1.8 2.3 1 1 1 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Proteasome PF00227.26 KXS09180.1 - 6.1e-48 162.8 0.4 6.9e-48 162.7 0.4 1.0 1 0 0 1 1 1 1 Proteasome subunit YkuD PF03734.14 KXS09180.1 - 0.02 15.3 0.2 0.063 13.7 0.2 1.7 1 1 0 1 1 1 0 L,D-transpeptidase catalytic domain ProRS-C_1 PF09180.11 KXS09182.1 - 1.7e-25 89.0 0.3 6.7e-25 87.1 0.3 2.1 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.25 KXS09182.1 - 1e-18 68.0 0.0 2.7e-18 66.6 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KXS09182.1 - 2.3e-17 62.9 0.0 6.6e-17 61.4 0.0 1.8 1 0 0 1 1 1 1 Anticodon binding domain tRNA_edit PF04073.15 KXS09182.1 - 3e-12 46.7 0.3 5.8e-12 45.8 0.3 1.5 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain RRM_1 PF00076.22 KXS09183.1 - 6.8e-15 54.7 0.0 1e-14 54.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SprT-like PF10263.9 KXS09184.1 - 1.5e-26 92.5 0.0 2.3e-26 91.9 0.0 1.3 1 0 0 1 1 1 1 SprT-like family WLM PF08325.10 KXS09184.1 - 0.069 13.2 2.6 0.22 11.6 0.0 2.2 2 0 0 2 2 2 0 WLM domain ABATE PF07336.11 KXS09184.1 - 0.099 13.3 1.3 0.26 11.9 0.6 2.0 2 0 0 2 2 2 0 Putative stress-induced transcription regulator zf_UBZ PF18439.1 KXS09184.1 - 0.19 11.3 0.0 0.19 11.3 0.0 1.9 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Abhydrolase_1 PF00561.20 KXS09185.1 - 1.9e-28 99.8 0.3 1.9e-28 99.8 0.3 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXS09185.1 - 4e-18 66.8 5.3 8.2e-18 65.8 5.3 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXS09185.1 - 3e-16 59.4 0.0 1.7e-15 57.0 0.0 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.20 KXS09185.1 - 1.6e-05 24.7 0.1 7.7e-05 22.5 0.1 2.0 1 1 0 1 1 1 1 Putative esterase Ser_hydrolase PF06821.13 KXS09185.1 - 9.2e-05 22.4 0.0 0.00037 20.4 0.0 2.0 2 0 0 2 2 2 1 Serine hydrolase Chlorophyllase2 PF12740.7 KXS09185.1 - 0.00055 18.9 0.0 0.00084 18.3 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_5 PF12695.7 KXS09185.1 - 0.00068 19.4 0.0 0.0013 18.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.14 KXS09185.1 - 0.0022 16.7 0.0 0.0036 16.0 0.0 1.2 1 0 0 1 1 1 1 Ndr family Abhydrolase_3 PF07859.13 KXS09185.1 - 0.0035 17.2 0.0 0.0084 16.0 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KXS09185.1 - 0.0059 16.1 0.0 0.013 15.0 0.0 1.6 1 0 0 1 1 1 1 Prolyl oligopeptidase family LIDHydrolase PF10230.9 KXS09185.1 - 0.018 14.6 0.0 0.031 13.8 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase UPF0227 PF05728.12 KXS09185.1 - 0.037 14.0 0.0 0.068 13.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) DUF915 PF06028.11 KXS09185.1 - 0.04 13.3 0.0 0.083 12.2 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) PGAP1 PF07819.13 KXS09185.1 - 0.049 13.3 0.0 0.096 12.4 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Lipase_3 PF01764.25 KXS09185.1 - 0.15 12.0 0.0 0.32 10.9 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) Pneumo_att_G PF05539.11 KXS09185.1 - 0.68 9.5 3.5 1.2 8.6 3.5 1.3 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G ubiquitin PF00240.23 KXS09186.1 - 8.4e-70 230.5 4.8 3.7e-34 116.3 0.4 2.2 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.8 KXS09186.1 - 9.6e-34 115.1 5.7 3.3e-16 58.9 0.5 2.2 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KXS09186.1 - 3.4e-12 46.7 1.0 0.0002 21.8 0.1 3.2 2 2 0 2 2 2 2 Ubiquitin-like domain TBK1_ULD PF18396.1 KXS09186.1 - 1.5e-07 31.2 0.4 0.02 14.8 0.1 2.3 2 0 0 2 2 2 2 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 KXS09186.1 - 2.2e-07 31.1 0.6 0.027 14.8 0.1 2.2 1 1 1 2 2 2 2 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 KXS09186.1 - 6e-07 29.5 0.3 0.05 13.7 0.0 2.8 2 2 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 KXS09186.1 - 1.8e-06 28.4 0.1 0.069 13.7 0.0 2.2 1 1 0 2 2 2 2 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 KXS09186.1 - 0.00027 20.9 8.3 6.8 6.8 0.2 4.1 4 0 0 4 4 4 2 Ubiquitin-like domain Sde2_N_Ubi PF13019.6 KXS09186.1 - 0.00062 19.6 0.0 1.4 8.8 0.0 2.4 1 1 1 2 2 2 2 Silencing defective 2 N-terminal ubiquitin domain DUF3861 PF12977.7 KXS09186.1 - 0.0056 16.8 0.2 5.1 7.3 0.0 2.3 2 0 0 2 2 2 2 Domain of Unknown Function with PDB structure (DUF3861) ACT_5 PF13710.6 KXS09186.1 - 0.027 14.3 0.4 8.9 6.2 0.0 2.4 2 0 0 2 2 2 0 ACT domain DUF2870 PF11069.8 KXS09186.1 - 0.048 14.0 0.0 15 6.0 0.0 2.7 2 2 0 2 2 2 0 Protein of unknown function (DUF2870) ACT_4 PF13291.6 KXS09186.1 - 0.092 13.3 0.1 36 5.0 0.0 2.8 3 0 0 3 3 3 0 ACT domain Big_7 PF17957.1 KXS09186.1 - 0.094 13.5 0.8 26 5.7 0.0 2.6 3 0 0 3 3 3 0 Bacterial Ig domain Plexin_cytopl PF08337.12 KXS09186.1 - 0.23 10.1 3.9 12 4.4 0.3 3.2 2 1 0 3 3 3 0 Plexin cytoplasmic RasGAP domain Tash_PEST PF07708.11 KXS09186.1 - 0.43 10.8 9.6 4.2 7.7 1.5 2.3 2 0 0 2 2 2 0 Tash protein PEST motif HSCB_C PF07743.13 KXS09187.1 - 1.4e-14 54.3 6.6 2.8e-14 53.4 4.0 2.2 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 KXS09187.1 - 2.7e-05 24.2 0.0 6.6e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain zf-ribbon_3 PF13248.6 KXS09187.1 - 0.011 15.1 0.7 0.024 14.1 0.7 1.5 1 0 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_2 PF13240.6 KXS09187.1 - 0.051 13.3 0.1 0.092 12.5 0.1 1.4 1 0 0 1 1 1 0 zinc-ribbon domain zf-tcix PF14952.6 KXS09187.1 - 0.13 11.9 0.3 0.23 11.1 0.3 1.3 1 0 0 1 1 1 0 Putative treble-clef, zinc-finger, Zn-binding Ribosomal_L40e PF01020.17 KXS09187.1 - 0.15 12.0 0.1 0.31 11.0 0.1 1.4 1 0 0 1 1 1 0 Ribosomal L40e family DUF2508 PF10704.9 KXS09187.1 - 0.44 10.7 2.3 1.5 9.1 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2508) FYVE PF01363.21 KXS09188.1 - 1.3e-15 57.3 12.6 2.3e-15 56.5 12.6 1.4 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 KXS09188.1 - 0.29 11.4 3.6 0.6 10.3 3.6 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger adh_short PF00106.25 KXS09189.1 - 2.5e-19 69.5 0.9 6.9e-08 32.2 0.1 3.6 3 1 0 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXS09189.1 - 6.2e-10 39.0 1.0 0.0029 17.2 0.1 3.1 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Prot_ATP_OB_N PF17758.1 KXS09191.1 - 0.084 12.5 0.1 0.13 11.9 0.1 1.3 1 0 0 1 1 1 0 Proteasomal ATPase OB N-terminal domain RGS PF00615.19 KXS09192.1 - 0.079 13.2 0.0 0.094 13.0 0.0 1.2 1 0 0 1 1 1 0 Regulator of G protein signaling domain RGS PF00615.19 KXS09193.1 - 3.7e-05 24.0 0.0 0.0004 20.6 0.0 2.1 1 1 0 1 1 1 1 Regulator of G protein signaling domain FA_desaturase PF00487.24 KXS09194.1 - 5.6e-14 52.6 21.6 5.6e-14 52.6 21.6 1.5 1 1 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 KXS09194.1 - 1.6e-11 44.2 0.0 3.1e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain SH3_9 PF14604.6 KXS09197.1 - 7.8e-16 57.7 0.4 1.6e-07 31.1 0.1 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 KXS09197.1 - 1.3e-12 47.1 0.0 2.3e-05 23.9 0.0 2.3 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 KXS09197.1 - 8e-05 22.2 0.0 0.071 12.8 0.0 2.3 2 0 0 2 2 2 2 Variant SH3 domain PFK PF00365.20 KXS09198.1 - 4.8e-56 190.2 0.0 5.9e-56 189.9 0.0 1.1 1 0 0 1 1 1 1 Phosphofructokinase EutA PF06277.11 KXS09198.1 - 0.016 14.1 0.0 0.022 13.6 0.0 1.1 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutA Pkinase PF00069.25 KXS09199.1 - 1.4e-70 237.7 0.0 1.7e-70 237.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS09199.1 - 4.8e-30 104.7 0.0 6.2e-30 104.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 KXS09199.1 - 1.2e-14 54.7 2.7 2.9e-14 53.5 2.7 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 KXS09199.1 - 5.7e-05 22.6 0.0 0.00015 21.2 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KXS09199.1 - 0.016 14.6 0.0 0.024 14.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KXS09199.1 - 0.047 12.6 0.0 0.063 12.2 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 KXS09199.1 - 0.07 13.0 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family AA_permease_2 PF13520.6 KXS09200.1 - 1.1e-58 199.1 45.4 1.4e-58 198.8 45.4 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXS09200.1 - 5.6e-24 84.6 40.7 7.8e-24 84.1 40.7 1.1 1 0 0 1 1 1 1 Amino acid permease Bax1-I PF01027.20 KXS09202.1 - 1e-21 77.7 18.2 1.2e-21 77.5 18.2 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF1003 PF06210.11 KXS09202.1 - 0.035 14.2 0.2 0.068 13.3 0.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1003) Peptidase_U4 PF03419.13 KXS09202.1 - 2.1 7.6 7.9 0.46 9.7 4.6 1.6 1 1 0 1 1 1 0 Sporulation factor SpoIIGA Abhydrolase_3 PF07859.13 KXS09203.1 - 1.2e-51 175.6 0.2 2e-51 174.9 0.2 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KXS09203.1 - 5.1e-11 42.1 0.1 1.4e-10 40.7 0.1 1.6 1 1 0 1 1 1 1 Carboxylesterase family Say1_Mug180 PF10340.9 KXS09203.1 - 4.6e-05 22.4 0.0 5.7e-05 22.1 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Chlorophyllase2 PF12740.7 KXS09203.1 - 0.0044 16.0 0.3 0.55 9.1 0.0 2.4 3 0 0 3 3 3 2 Chlorophyllase enzyme Esterase_phd PF10503.9 KXS09203.1 - 0.007 15.9 1.3 0.23 10.9 0.2 2.3 2 0 0 2 2 2 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 KXS09203.1 - 0.019 14.4 0.0 0.03 13.8 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family AXE1 PF05448.12 KXS09203.1 - 0.036 12.7 0.0 0.38 9.4 0.0 2.0 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Hydrolase_4 PF12146.8 KXS09203.1 - 0.058 12.7 0.0 6.9 5.9 0.0 2.4 3 0 0 3 3 3 0 Serine aminopeptidase, S33 Chlorophyllase PF07224.11 KXS09203.1 - 0.076 12.0 0.1 1.2 8.1 0.0 2.0 2 0 0 2 2 2 0 Chlorophyllase MtN3_slv PF03083.16 KXS09204.1 - 1.5e-34 117.9 1.4 1.2e-19 70.1 0.1 2.2 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange DUF981 PF06168.11 KXS09204.1 - 0.12 12.2 10.8 0.076 12.9 8.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF981) InaF-motif PF15018.6 KXS09204.1 - 0.14 12.0 0.5 0.14 12.0 0.5 2.3 2 0 0 2 2 2 0 TRP-interacting helix Piwi PF02171.17 KXS09205.1 - 3.4e-41 141.4 0.0 9.1e-32 110.5 0.0 2.3 1 1 1 2 2 2 2 Piwi domain RRM_1 PF00076.22 KXS09205.1 - 1.3e-22 79.4 0.0 7e-13 48.2 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ArgoL2 PF16488.5 KXS09205.1 - 7.9e-12 45.3 0.1 1.8e-11 44.2 0.1 1.7 1 0 0 1 1 1 1 Argonaute linker 2 domain PAZ PF02170.22 KXS09205.1 - 6.3e-10 39.0 0.0 1.3e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 PAZ domain ArgoL1 PF08699.10 KXS09205.1 - 1.7e-06 27.6 0.0 4.3e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoMid PF16487.5 KXS09205.1 - 0.037 14.3 0.0 0.085 13.1 0.0 1.6 1 0 0 1 1 1 0 Mid domain of argonaute VHS PF00790.19 KXS09207.1 - 1.1e-33 116.1 0.6 1.9e-33 115.3 0.6 1.4 1 0 0 1 1 1 1 VHS domain SH3_9 PF14604.6 KXS09207.1 - 1.7e-13 50.2 0.1 3.9e-13 49.0 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXS09207.1 - 6.8e-13 48.0 0.1 1.4e-12 47.0 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KXS09207.1 - 1.8e-11 43.5 0.0 3.2e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain GAT PF03127.14 KXS09207.1 - 5.7e-10 39.4 1.1 5.7e-10 39.4 1.1 2.2 3 0 0 3 3 3 1 GAT domain UIM PF02809.20 KXS09207.1 - 0.00038 20.2 3.8 0.00092 19.0 3.8 1.7 1 0 0 1 1 1 1 Ubiquitin interaction motif RAP80_UIM PF18282.1 KXS09207.1 - 0.068 12.9 0.3 0.22 11.4 0.3 1.8 1 0 0 1 1 1 0 RAP80 N-terminal ubiquitin interaction motif Hrs_helical PF12210.8 KXS09207.1 - 2.4 8.8 4.2 2.1 9.0 0.4 2.5 3 0 0 3 3 3 0 Hepatocyte growth factor-regulated tyrosine kinase substrate ADIP PF11559.8 KXS09208.1 - 1.3e-26 93.5 10.6 1.3e-26 93.5 10.6 2.7 2 1 1 3 3 3 1 Afadin- and alpha -actinin-Binding Exonuc_VII_L PF02601.15 KXS09208.1 - 0.0003 20.5 15.6 0.011 15.4 8.2 2.3 2 0 0 2 2 2 2 Exonuclease VII, large subunit EzrA PF06160.12 KXS09208.1 - 1.3 7.1 17.2 1.2 7.2 10.2 2.2 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA Spc7 PF08317.11 KXS09208.1 - 3.9 6.3 32.8 0.047 12.6 1.0 3.4 4 0 0 4 4 4 0 Spc7 kinetochore protein Lebercilin PF15619.6 KXS09208.1 - 6.9 6.3 35.0 0.39 10.3 9.7 2.6 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DUF3584 PF12128.8 KXS09208.1 - 9.6 3.6 27.7 0.76 7.2 12.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) LysM PF01476.20 KXS09209.1 - 1.1e-28 99.0 0.0 2.4e-08 33.9 0.0 4.4 4 0 0 4 4 4 4 LysM domain LysM PF01476.20 KXS09210.1 - 1.3e-24 85.9 0.2 5e-11 42.5 0.0 2.2 2 0 0 2 2 2 2 LysM domain Sugar-bind PF04198.13 KXS09210.1 - 0.0025 17.0 0.1 0.0032 16.6 0.1 1.1 1 0 0 1 1 1 1 Putative sugar-binding domain Tcp10_C PF07202.13 KXS09212.1 - 5.8e-21 75.2 0.1 1.1e-20 74.3 0.1 1.4 1 0 0 1 1 1 1 T-complex protein 10 C-terminus End3 PF12761.7 KXS09212.1 - 0.15 12.2 12.4 0.02 15.1 7.8 1.8 1 1 1 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 Atg14 PF10186.9 KXS09212.1 - 0.5 9.4 11.6 0.89 8.6 11.6 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 APG6_N PF17675.1 KXS09212.1 - 1 9.9 22.2 3.2 8.3 2.9 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region TPR_MLP1_2 PF07926.12 KXS09212.1 - 1.7 8.7 21.2 0.46 10.6 2.2 2.8 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein SWIRM-assoc_1 PF16495.5 KXS09212.1 - 8.3 6.4 12.7 0.49 10.4 4.7 2.7 2 0 0 2 2 2 0 SWIRM-associated region 1 RNA_pol_Rpb4 PF03874.16 KXS09213.1 - 6.1e-11 42.7 0.3 7e-11 42.5 0.3 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 Pkinase PF00069.25 KXS09215.1 - 1.3e-57 195.2 0.0 1.6e-57 194.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS09215.1 - 7.3e-42 143.4 0.0 9.6e-42 143.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXS09215.1 - 8e-05 22.1 0.0 0.00016 21.1 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KXS09215.1 - 0.00021 20.2 0.0 0.00031 19.7 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KXS09215.1 - 0.00069 19.6 0.0 0.0015 18.5 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KXS09215.1 - 0.013 14.8 0.0 0.022 14.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KXS09215.1 - 0.015 14.3 0.0 0.16 10.8 0.0 2.0 2 0 0 2 2 2 0 Haspin like kinase domain ABC1 PF03109.16 KXS09215.1 - 0.15 12.2 0.0 0.29 11.3 0.0 1.4 1 0 0 1 1 1 0 ABC1 family APH PF01636.23 KXS09216.1 - 3.1e-07 30.6 0.6 0.056 13.3 0.0 3.2 2 1 1 3 3 3 3 Phosphotransferase enzyme family Kdo PF06293.14 KXS09216.1 - 4.6e-06 26.1 0.0 0.0031 16.9 0.0 2.5 3 0 0 3 3 3 2 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KXS09216.1 - 0.00067 19.3 0.0 0.79 9.3 0.0 2.2 2 0 0 2 2 2 2 RIO1 family Pkinase PF00069.25 KXS09216.1 - 0.0038 16.6 0.0 0.0078 15.6 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain ATP_synt_H PF05493.13 KXS09217.1 - 3.9e-16 59.3 0.8 4.7e-16 59.0 0.8 1.1 1 0 0 1 1 1 1 ATP synthase subunit H DUF4134 PF13572.6 KXS09217.1 - 0.057 13.7 0.0 0.069 13.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4134) Ribosomal_L11_N PF03946.14 KXS09218.1 - 6.4e-26 90.0 1.9 5.3e-25 87.0 0.9 2.2 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 KXS09218.1 - 1.3e-23 83.3 0.7 2e-23 82.6 0.7 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Rhodanese PF00581.20 KXS09220.1 - 1.8e-10 41.3 0.0 2.4e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain adh_short PF00106.25 KXS09221.1 - 7.9e-14 51.6 0.1 1.3e-13 50.9 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXS09221.1 - 1.5e-13 50.9 0.1 2e-13 50.5 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KXS09221.1 - 7e-08 32.2 0.2 1.1e-06 28.3 0.2 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXS09221.1 - 0.0062 16.0 0.0 0.42 9.9 0.0 2.3 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KXS09221.1 - 0.008 15.3 0.1 0.013 14.6 0.1 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Aldedh PF00171.22 KXS09222.1 - 7.7e-17 60.9 4.6 2.5e-10 39.5 3.2 2.6 2 1 0 2 2 2 2 Aldehyde dehydrogenase family Clat_adaptor_s PF01217.20 KXS09223.1 - 5.3e-58 195.0 2.1 5.9e-58 194.8 2.1 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain PCAF_N PF06466.11 KXS09223.1 - 0.011 15.4 0.1 0.014 15.0 0.1 1.2 1 0 0 1 1 1 0 PCAF (P300/CBP-associated factor) N-terminal domain Rep_fac-A_C PF08646.10 KXS09224.1 - 6.4e-54 181.7 0.0 2.3e-52 176.6 0.0 2.4 2 0 0 2 2 2 1 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 KXS09224.1 - 1.4e-31 108.3 0.0 3.2e-31 107.1 0.0 1.6 1 0 0 1 1 1 1 Replication protein A OB domain Rep-A_N PF04057.12 KXS09224.1 - 2.3e-23 82.1 0.1 6.1e-23 80.8 0.1 1.8 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.25 KXS09224.1 - 3.4e-10 39.8 1.0 3.8e-07 30.0 0.1 3.6 3 0 0 3 3 3 1 OB-fold nucleic acid binding domain CDC24_OB3 PF17244.2 KXS09224.1 - 0.0013 18.5 0.1 0.9 9.2 0.0 2.7 3 0 0 3 3 3 2 Cell division control protein 24, OB domain 3 IBR PF01485.21 KXS09224.1 - 0.14 12.4 1.5 0.27 11.5 1.5 1.4 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain zf-AN1 PF01428.16 KXS09224.1 - 0.17 12.1 1.1 0.27 11.4 1.1 1.3 1 0 0 1 1 1 0 AN1-like Zinc finger Kinesin PF00225.23 KXS09225.1 - 1.8e-112 375.6 0.0 2.2e-112 375.3 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KXS09225.1 - 1.9e-27 96.0 0.0 5.3e-27 94.6 0.0 1.7 2 0 0 2 2 2 1 Microtubule binding AAA_7 PF12775.7 KXS09225.1 - 0.024 14.1 0.0 0.047 13.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Bac_DnaA PF00308.18 KXS09225.1 - 0.042 13.7 0.1 0.12 12.1 0.0 1.8 2 0 0 2 2 2 0 Bacterial dnaA protein AAA_22 PF13401.6 KXS09225.1 - 0.043 14.1 0.0 0.14 12.4 0.0 1.9 2 1 0 2 2 2 0 AAA domain Microtub_bind PF13931.6 KXS09226.1 - 0.0005 20.5 0.1 0.0005 20.5 0.1 2.6 3 0 0 3 3 3 1 Kinesin-associated microtubule-binding Baculo_PEP_C PF04513.12 KXS09226.1 - 0.0052 16.8 8.1 2.4 8.2 0.2 4.4 2 2 3 5 5 5 1 Baculovirus polyhedron envelope protein, PEP, C terminus Apolipoprotein PF01442.18 KXS09226.1 - 0.013 15.4 10.0 0.42 10.5 9.8 3.0 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Prominin PF05478.11 KXS09226.1 - 0.014 13.4 0.7 1.5 6.6 0.0 2.0 1 1 1 2 2 2 0 Prominin Tmemb_cc2 PF10267.9 KXS09226.1 - 0.11 11.6 5.1 0.016 14.4 0.8 1.7 2 0 0 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein DUF1640 PF07798.11 KXS09226.1 - 0.17 11.9 6.1 0.033 14.2 1.0 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1640) ApoLp-III PF07464.11 KXS09226.1 - 0.21 11.7 3.9 2.8 8.0 0.1 2.9 2 1 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) DUF1664 PF07889.12 KXS09226.1 - 0.23 11.5 2.8 18 5.4 0.3 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) BshC PF10079.9 KXS09226.1 - 0.28 9.9 3.8 5.3 5.7 0.4 2.2 2 0 0 2 2 2 0 Bacillithiol biosynthesis BshC CCDC24 PF15669.5 KXS09226.1 - 0.49 10.2 6.2 0.38 10.6 0.4 3.3 2 1 1 3 3 3 0 Coiled-coil domain-containing protein 24 family ZapB PF06005.12 KXS09226.1 - 1.5 9.3 7.6 1.2 9.6 0.2 3.5 4 0 0 4 4 4 0 Cell division protein ZapB YabA PF06156.13 KXS09226.1 - 1.9 9.2 4.8 1 10.0 0.6 2.7 3 2 0 3 3 3 0 Initiation control protein YabA CbiQ PF02361.16 KXS09228.1 - 0.089 12.4 0.0 0.1 12.2 0.0 1.0 1 0 0 1 1 1 0 Cobalt transport protein GTP_EFTU_D3 PF03143.17 KXS09229.1 - 5.2e-42 142.7 0.0 1.1e-41 141.7 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KXS09229.1 - 2.5e-14 53.4 0.2 2.5e-14 53.4 0.2 2.3 3 0 0 3 3 3 1 Elongation factor Tu domain 2 GTP_EFTU PF00009.27 KXS09229.1 - 5e-11 42.5 0.3 1e-10 41.5 0.3 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D4 PF14578.6 KXS09229.1 - 0.012 15.5 0.1 0.012 15.5 0.1 2.3 3 0 0 3 3 3 0 Elongation factor Tu domain 4 Semialdhyde_dhC PF02774.18 KXS09229.1 - 0.019 15.1 0.4 0.04 14.0 0.1 1.7 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, dimerisation domain zf-RING_2 PF13639.6 KXS09233.1 - 2.2e-09 37.5 6.5 4.4e-09 36.5 6.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KXS09233.1 - 7.4e-09 35.3 6.3 1.3e-08 34.6 6.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXS09233.1 - 2.1e-07 30.6 7.7 3.7e-07 29.9 7.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KXS09233.1 - 3.3e-07 30.1 3.1 5.3e-07 29.4 3.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXS09233.1 - 5.1e-06 26.4 4.5 1.9e-05 24.6 3.6 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 KXS09233.1 - 0.00018 21.4 4.9 0.00018 21.4 4.9 1.7 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KXS09233.1 - 0.00062 19.6 9.1 0.0036 17.1 8.8 2.1 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 KXS09233.1 - 0.0047 17.2 7.5 0.0047 17.2 7.5 2.1 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KXS09233.1 - 0.059 13.4 2.1 0.12 12.5 2.1 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 KXS09233.1 - 0.07 13.3 8.3 0.14 12.4 8.3 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Zn-C2H2_12 PF18112.1 KXS09233.1 - 0.14 12.6 0.4 8.7 6.9 0.0 2.6 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zf-RING_10 PF16685.5 KXS09233.1 - 0.54 10.4 2.7 1 9.6 2.7 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_11 PF17123.5 KXS09233.1 - 1.7 8.5 4.7 3.5 7.4 4.7 1.6 1 0 0 1 1 1 0 RING-like zinc finger GATase PF00117.28 KXS09234.1 - 1.4e-06 28.2 0.0 2e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KXS09234.1 - 0.09 12.5 0.1 0.22 11.2 0.1 1.6 1 1 1 2 2 2 0 Peptidase C26 TLP1_add_C PF18313.1 KXS09235.1 - 1e-17 63.8 0.0 2.5e-17 62.6 0.0 1.6 1 0 0 1 1 1 1 Thiolase-like protein type 1 additional C-terminal domain DUF3712 PF12505.8 KXS09236.1 - 3.8e-09 36.9 0.4 5.7e-05 23.4 0.1 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF3712) Vac_ImportDeg PF09783.9 KXS09236.1 - 0.23 11.3 0.0 3.1 7.6 0.0 2.3 2 0 0 2 2 2 0 Vacuolar import and degradation protein GST_N_3 PF13417.6 KXS09237.1 - 1.7e-08 34.7 0.0 3.3e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KXS09237.1 - 3.7e-06 27.1 0.0 6.5e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KXS09237.1 - 0.00061 20.1 0.0 0.0012 19.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KXS09237.1 - 0.0073 16.3 0.1 0.017 15.1 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain HSF_DNA-bind PF00447.17 KXS09238.1 - 2.5e-31 108.2 1.1 4.6e-31 107.3 1.1 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding Response_reg PF00072.24 KXS09238.1 - 7.4e-26 90.5 0.4 2.2e-25 89.0 0.1 1.9 2 0 0 2 2 2 1 Response regulator receiver domain D5_N PF08706.11 KXS09238.1 - 0.023 14.9 0.1 0.023 14.9 0.1 1.6 2 0 0 2 2 2 0 D5 N terminal like DivIC PF04977.15 KXS09238.1 - 0.39 10.5 3.3 0.83 9.5 3.3 1.5 1 0 0 1 1 1 0 Septum formation initiator Pyr_redox_2 PF07992.14 KXS09239.1 - 1.1e-49 169.3 0.0 1.3e-49 169.0 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXS09239.1 - 9.3e-13 48.5 0.0 3.1e-10 40.5 0.1 3.0 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXS09239.1 - 0.01 15.1 1.1 0.52 9.5 0.0 2.4 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXS09239.1 - 0.023 14.9 0.0 1.6 9.0 0.0 3.1 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain TrkA_N PF02254.18 KXS09239.1 - 0.029 14.6 0.0 11 6.4 0.0 3.5 2 1 1 3 3 3 0 TrkA-N domain K_oxygenase PF13434.6 KXS09239.1 - 0.037 13.2 0.0 0.35 9.9 0.0 2.4 2 1 1 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KXS09239.1 - 0.084 12.4 0.0 15 5.1 0.0 2.5 2 1 1 3 3 3 0 FAD dependent oxidoreductase OB_NTP_bind PF07717.16 KXS09241.1 - 8.6e-12 45.3 0.0 3.3e-11 43.4 0.0 2.0 1 1 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 KXS09241.1 - 1.2e-11 44.8 0.1 1.2e-11 44.8 0.1 3.0 3 1 0 3 3 3 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KXS09241.1 - 3e-10 40.4 0.0 6.6e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 KXS09241.1 - 0.0022 18.3 0.0 0.009 16.3 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KXS09241.1 - 0.0067 16.8 0.0 0.014 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 KXS09241.1 - 0.012 14.7 0.0 0.022 13.8 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein DEAD PF00270.29 KXS09241.1 - 0.02 14.7 0.3 0.15 11.8 0.3 2.2 1 1 0 1 1 1 0 DEAD/DEAH box helicase ATPase PF06745.13 KXS09241.1 - 0.11 11.8 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_23 PF13476.6 KXS09241.1 - 3.9 7.9 0.0 3.9 7.9 0.0 3.5 2 1 1 3 3 3 0 AAA domain Glyoxalase PF00903.25 KXS09243.1 - 4.1e-11 43.2 0.0 5.1e-11 42.9 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily PLDc PF00614.22 KXS09244.1 - 3e-13 49.4 2.4 3.6e-06 26.9 0.3 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 KXS09244.1 - 1.5e-12 47.6 0.2 4.5e-06 26.6 0.0 3.6 2 1 0 2 2 2 2 PLD-like domain Pyr_redox_2 PF07992.14 KXS09245.1 - 2.7e-40 138.4 0.0 3.6e-40 138.0 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXS09245.1 - 1.3e-10 41.7 0.1 8.2e-10 39.1 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXS09245.1 - 0.016 15.4 0.3 0.13 12.5 0.0 2.8 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain HAD_2 PF13419.6 KXS09245.1 - 0.17 12.0 0.1 0.34 11.0 0.1 1.4 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Pyr_redox_3 PF13738.6 KXS09245.1 - 0.23 10.6 2.1 0.96 8.6 0.0 2.1 1 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GCN5L1 PF06320.13 KXS09246.1 - 3.9e-27 94.7 5.1 4.3e-27 94.5 5.1 1.0 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) SLATT_1 PF18181.1 KXS09246.1 - 0.0036 17.2 0.2 0.0061 16.5 0.2 1.4 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain 1 LOH1CR12 PF10158.9 KXS09246.1 - 0.021 14.8 1.5 0.054 13.5 1.5 1.6 1 1 0 1 1 1 0 Tumour suppressor protein MIS13 PF08202.11 KXS09246.1 - 0.03 13.6 1.2 0.036 13.3 1.2 1.2 1 0 0 1 1 1 0 Mis12-Mtw1 protein family Foie-gras_1 PF11817.8 KXS09246.1 - 0.058 13.0 0.5 0.066 12.8 0.5 1.1 1 0 0 1 1 1 0 Foie gras liver health family 1 Sec2p PF06428.11 KXS09246.1 - 0.069 13.1 3.7 0.1 12.6 3.3 1.5 1 1 0 1 1 1 0 GDP/GTP exchange factor Sec2p Peptidase_S39 PF02122.15 KXS09246.1 - 0.1 12.1 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Peptidase S39 Prefoldin_2 PF01920.20 KXS09246.1 - 0.14 12.1 4.7 6.8 6.7 0.1 2.2 2 0 0 2 2 2 0 Prefoldin subunit Baculo_PEP_C PF04513.12 KXS09246.1 - 0.53 10.3 5.7 10 6.1 5.7 2.0 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus LRR_4 PF12799.7 KXS09247.1 - 4.3e-17 61.9 11.3 1.6e-05 25.1 0.2 5.0 1 1 6 7 7 7 7 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KXS09247.1 - 1.1e-16 60.8 0.3 8.1e-13 48.2 0.3 2.3 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 KXS09247.1 - 2.1e-12 46.6 8.9 0.00057 19.6 0.0 3.8 3 1 0 3 3 3 3 Leucine rich repeat LRR_6 PF13516.6 KXS09247.1 - 0.0079 16.2 11.2 0.47 10.6 0.0 5.5 7 0 0 7 7 7 2 Leucine Rich repeat LRR_1 PF00560.33 KXS09247.1 - 1.1 10.0 10.3 12 6.9 0.1 4.9 5 1 0 5 5 5 0 Leucine Rich Repeat Menin PF05053.13 KXS09247.1 - 1.3 7.3 5.8 1.8 6.8 5.8 1.1 1 0 0 1 1 1 0 Menin Ipi1_N PF12333.8 KXS09248.1 - 1.5e-10 41.6 0.4 1.5e-10 41.6 0.4 3.2 3 0 0 3 3 3 1 Rix1 complex component involved in 60S ribosome maturation Vac14_Fab1_bd PF12755.7 KXS09248.1 - 0.0047 17.5 0.0 0.045 14.3 0.0 2.5 2 0 0 2 2 2 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 KXS09248.1 - 0.018 15.1 0.0 0.045 13.8 0.0 1.6 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 GatB_Yqey PF02637.18 KXS09248.1 - 0.082 12.8 0.1 0.19 11.6 0.1 1.6 1 0 0 1 1 1 0 GatB domain Pkinase PF00069.25 KXS09249.1 - 3.4e-40 138.1 0.0 4.5e-40 137.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS09249.1 - 1.7e-20 73.4 0.0 2.2e-20 73.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXS09249.1 - 0.0047 16.9 0.0 0.046 13.6 0.1 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family ABC2_membrane PF01061.24 KXS09251.1 - 3.1e-73 245.6 54.2 1e-39 136.1 16.8 2.5 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 KXS09251.1 - 1.3e-27 97.0 0.1 7e-15 55.8 0.0 2.8 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.12 KXS09251.1 - 2.9e-22 78.4 9.6 2.7e-15 56.0 0.0 3.9 3 0 0 3 3 3 2 CDR ABC transporter ABC_trans_N PF14510.6 KXS09251.1 - 0.00034 21.2 0.0 0.00098 19.7 0.0 1.8 1 0 0 1 1 1 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 KXS09251.1 - 0.00085 18.5 42.8 0.0098 15.0 12.8 3.5 2 1 1 3 3 3 2 ABC-2 family transporter protein SMC_N PF02463.19 KXS09251.1 - 0.0046 16.4 0.0 0.053 13.0 0.1 2.5 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KXS09251.1 - 0.03 14.7 0.1 0.15 12.4 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_21 PF13304.6 KXS09251.1 - 0.043 13.6 0.2 0.12 12.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system ACT PF01842.25 KXS09251.1 - 0.12 12.1 0.1 0.5 10.2 0.1 2.0 1 0 0 1 1 1 0 ACT domain p450 PF00067.22 KXS09252.1 - 9.8e-36 123.5 0.0 4e-29 101.7 0.0 3.0 2 1 0 2 2 2 2 Cytochrome P450 NmrA PF05368.13 KXS09253.1 - 2.6e-26 92.6 0.0 3.3e-26 92.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXS09253.1 - 1.7e-09 37.8 0.2 3.8e-09 36.7 0.2 1.6 1 1 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KXS09253.1 - 3.2e-05 24.2 0.2 4.9e-05 23.6 0.2 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 KXS09253.1 - 0.015 14.7 0.1 0.056 12.9 0.1 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 KXS09253.1 - 0.06 13.8 0.0 0.1 13.0 0.0 1.3 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.10 KXS09253.1 - 0.083 12.8 0.2 0.12 12.3 0.2 1.2 1 0 0 1 1 1 0 KR domain DUF3798 PF12683.7 KXS09253.1 - 0.22 10.9 0.0 0.33 10.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3798) NmrA PF05368.13 KXS09254.1 - 8.4e-06 25.5 0.0 8.4e-06 25.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family Helicase_C PF00271.31 KXS09255.1 - 2.7e-11 43.8 0.0 4.9e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Suv3_C_1 PF18147.1 KXS09255.1 - 1.2e-08 34.7 0.0 2.2e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Suv3 C-terminal domain 1 AAA_22 PF13401.6 KXS09255.1 - 0.0057 16.9 0.0 0.012 15.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KXS09255.1 - 0.037 13.7 0.2 0.23 11.1 0.2 2.2 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KXS09255.1 - 0.062 13.3 0.0 0.15 12.1 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.6 KXS09255.1 - 0.1 12.4 0.8 0.26 11.1 0.7 1.5 1 1 0 1 1 1 0 AAA domain MazG PF03819.17 KXS09255.1 - 0.15 12.3 0.0 0.28 11.4 0.0 1.4 1 0 0 1 1 1 0 MazG nucleotide pyrophosphohydrolase domain DUF3506 PF12014.8 KXS09256.1 - 1.3e-09 38.2 0.0 4.8e-09 36.4 0.0 1.9 2 1 0 2 2 2 1 Domain of unknown function (DUF3506) ECSCR PF15820.5 KXS09257.1 - 0.015 15.1 0.3 0.035 13.9 0.3 1.6 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator dCache_1 PF02743.18 KXS09257.1 - 0.022 14.5 2.1 0.095 12.5 1.6 2.0 1 1 1 2 2 2 0 Cache domain CEP19 PF14933.6 KXS09258.1 - 2.4e-20 73.5 0.0 5.1e-20 72.4 0.0 1.5 1 0 0 1 1 1 1 CEP19-like protein F-box-like PF12937.7 KXS09259.1 - 0.0012 18.7 0.0 0.0029 17.4 0.0 1.6 1 0 0 1 1 1 1 F-box-like AA_permease_2 PF13520.6 KXS09262.1 - 4.8e-45 154.2 52.2 6.7e-45 153.7 52.2 1.2 1 0 0 1 1 1 1 Amino acid permease Glyco_hydro_16 PF00722.21 KXS09262.1 - 7.6e-18 64.6 2.1 1.1e-17 64.1 0.9 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 AA_permease PF00324.21 KXS09262.1 - 3.4e-15 55.6 47.8 4.9e-15 55.1 47.8 1.1 1 0 0 1 1 1 1 Amino acid permease CD34_antigen PF06365.12 KXS09262.1 - 2 7.9 3.0 0.65 9.6 0.1 1.6 2 0 0 2 2 2 0 CD34/Podocalyxin family AA_permease_2 PF13520.6 KXS09263.1 - 6.4e-46 157.0 49.5 8e-46 156.7 49.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXS09263.1 - 1.2e-16 60.4 44.7 1.5e-16 60.0 44.7 1.1 1 0 0 1 1 1 1 Amino acid permease SWIM PF04434.17 KXS09265.1 - 3.9e-07 29.6 0.1 1.3e-06 28.0 0.1 1.9 1 0 0 1 1 1 1 SWIM zinc finger PRESAN PF09687.10 KXS09265.1 - 0.022 15.3 0.6 0.056 14.0 0.6 1.6 1 0 0 1 1 1 0 Plasmodium RESA N-terminal MULE PF10551.9 KXS09265.1 - 0.088 13.2 0.1 8 7.0 0.0 2.8 2 0 0 2 2 2 0 MULE transposase domain MCR PF18509.1 KXS09265.1 - 0.72 9.5 6.2 2.3 7.8 0.2 3.1 3 0 0 3 3 3 0 Magnetochrome domain Zn_clus PF00172.18 KXS09266.1 - 0.0011 19.1 2.2 0.0011 19.1 2.2 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4777 PF16007.5 KXS09267.1 - 0.013 15.7 0.0 0.023 14.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4777) ODV-E18 PF10717.9 KXS09271.1 - 0.27 11.1 2.0 0.51 10.2 2.0 1.4 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 DGF-1_4 PF11024.8 KXS09272.1 - 0.015 16.1 0.3 0.023 15.5 0.3 1.3 1 0 0 1 1 1 0 Dispersed gene family protein 1 of Trypanosoma cruzi region 4 LRAT PF04970.13 KXS09273.1 - 7.3e-07 29.5 0.0 4.5e-05 23.7 0.1 2.2 2 0 0 2 2 2 1 Lecithin retinol acyltransferase Peptidase_C97 PF05903.14 KXS09273.1 - 0.0078 16.0 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain Ac81 PF05820.11 KXS09273.1 - 0.034 13.7 0.7 1.1 8.8 0.1 2.1 2 0 0 2 2 2 0 Baculoviridae AC81 OsmC PF02566.19 KXS09274.1 - 1.1e-11 45.1 0.0 5.3e-11 42.9 0.0 1.8 2 0 0 2 2 2 1 OsmC-like protein Ank_2 PF12796.7 KXS09275.1 - 3.1e-05 24.5 6.7 0.0046 17.5 0.6 2.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 KXS09275.1 - 4.4e-05 23.7 1.4 0.05 14.1 0.1 3.2 2 1 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 KXS09275.1 - 6.7e-05 23.4 0.5 0.0075 16.8 0.0 3.2 1 1 2 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXS09275.1 - 0.00045 20.5 1.4 1.1 9.7 0.0 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXS09275.1 - 0.00055 20.2 0.3 0.66 10.7 0.0 3.5 4 0 0 4 4 4 1 Ankyrin repeat Asparaginase_II PF06089.12 KXS09275.1 - 0.011 14.8 0.2 0.012 14.6 0.2 1.2 1 0 0 1 1 1 0 L-asparaginase II Oxysterol_BP PF01237.18 KXS09277.1 - 1.8e-45 155.4 0.1 5.3e-37 127.5 0.0 3.2 2 1 0 2 2 2 2 Oxysterol-binding protein Voltage_CLC PF00654.20 KXS09279.1 - 4.2e-69 233.5 30.5 4.2e-69 233.5 30.5 2.0 2 1 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 KXS09279.1 - 8.7e-11 42.1 0.6 7.3e-08 32.7 0.1 2.6 2 0 0 2 2 2 2 CBS domain Cwf_Cwc_15 PF04889.12 KXS09280.1 - 0.087 12.5 6.8 0.13 12.0 6.8 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 KXS09280.1 - 0.42 8.8 5.2 0.49 8.5 5.2 1.1 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 KXS09280.1 - 1.9 6.5 8.5 2.5 6.1 8.5 1.2 1 0 0 1 1 1 0 DNA polymerase phi COPI_C PF06957.11 KXS09280.1 - 5.7 5.6 5.0 7 5.3 5.0 1.2 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus Pkinase PF00069.25 KXS09281.1 - 0.02 14.3 0.0 0.029 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain ALMT PF11744.8 KXS09285.1 - 1.2e-15 57.4 5.2 1.2e-15 57.4 5.2 1.9 2 0 0 2 2 2 1 Aluminium activated malate transporter FUSC PF04632.12 KXS09285.1 - 4.2e-14 52.0 10.4 4.2e-14 52.0 10.4 3.3 3 0 0 3 3 3 2 Fusaric acid resistance protein family FUSC_2 PF13515.6 KXS09285.1 - 3.7e-13 49.7 33.6 2.2e-11 43.9 11.2 3.3 3 1 0 3 3 3 2 Fusaric acid resistance protein-like ArAE_2 PF10334.9 KXS09285.1 - 9.4e-13 48.5 2.2 8.5e-11 42.1 0.2 2.3 2 0 0 2 2 2 2 Aromatic acid exporter family member 2 RRM_1 PF00076.22 KXS09286.1 - 6.8e-29 99.5 1.3 1.1e-17 63.6 0.0 2.9 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 KXS09286.1 - 0.00045 20.2 0.8 0.066 13.3 0.1 2.3 2 0 0 2 2 2 2 Limkain b1 RRM_7 PF16367.5 KXS09286.1 - 0.0041 17.2 0.0 0.014 15.5 0.0 1.8 1 1 1 2 2 2 1 RNA recognition motif Nup35_RRM_2 PF14605.6 KXS09286.1 - 0.032 14.2 0.1 0.22 11.5 0.0 2.2 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 KXS09286.1 - 0.04 14.0 0.7 0.44 10.6 0.2 2.2 2 0 0 2 2 2 0 RNA binding motif RRM_5 PF13893.6 KXS09286.1 - 0.049 13.2 0.0 2.8 7.6 0.0 2.1 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 KXS09286.1 - 0.15 12.3 0.1 3.6 7.8 0.0 2.2 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter JmjC PF02373.22 KXS09287.1 - 6e-14 52.5 0.0 1.6e-13 51.1 0.0 1.8 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 KXS09287.1 - 3.7e-13 49.8 0.0 6.9e-13 48.9 0.0 1.5 1 0 0 1 1 1 1 Cupin-like domain F-box-like PF12937.7 KXS09287.1 - 1.4e-05 24.8 0.4 3.7e-05 23.5 0.4 1.7 1 0 0 1 1 1 1 F-box-like EcKinase PF02958.20 KXS09287.1 - 0.19 11.0 0.0 5.6 6.2 0.0 2.1 2 0 0 2 2 2 0 Ecdysteroid kinase Ribosomal_S19 PF00203.21 KXS09288.1 - 1e-22 79.8 0.0 1.3e-22 79.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 BAG PF02179.16 KXS09289.1 - 4.8e-10 39.7 0.0 6.3e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 BAG domain ubiquitin PF00240.23 KXS09289.1 - 3e-06 26.9 0.0 5.5e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_4 PF18036.1 KXS09289.1 - 0.035 14.1 0.0 8.3 6.5 0.0 2.3 1 1 1 2 2 2 0 Ubiquitin-like domain EB PF01683.18 KXS09290.1 - 0.0019 18.4 7.2 0.0033 17.7 7.2 1.3 1 0 0 1 1 1 1 EB module PWI PF01480.17 KXS09291.1 - 4.3e-07 30.1 0.1 1e-06 28.9 0.1 1.6 1 0 0 1 1 1 1 PWI domain RRM_1 PF00076.22 KXS09291.1 - 8.9e-07 28.6 0.0 1.9e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Metallophos PF00149.28 KXS09292.1 - 1.2e-06 29.2 0.0 2.2e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase SSF PF00474.17 KXS09292.1 - 0.29 9.9 0.9 2.3 7.0 0.6 2.0 2 0 0 2 2 2 0 Sodium:solute symporter family Plant_vir_prot PF01307.17 KXS09293.1 - 0.017 15.3 0.3 0.037 14.2 0.3 1.6 1 1 0 1 1 1 0 Plant viral movement protein MFS_2 PF13347.6 KXS09293.1 - 0.027 13.0 0.2 0.03 12.9 0.2 1.0 1 0 0 1 1 1 0 MFS/sugar transport protein CbtB PF09489.10 KXS09293.1 - 0.1 12.7 0.2 0.1 12.7 0.2 2.1 2 0 0 2 2 2 0 Probable cobalt transporter subunit (CbtB) OppC_N PF12911.7 KXS09293.1 - 4.7 7.3 5.7 4.8 7.3 0.1 2.4 2 1 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C PAPS_reduct PF01507.19 KXS09294.1 - 7.7e-43 146.5 0.0 1.3e-42 145.8 0.0 1.3 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family SH3_9 PF14604.6 KXS09295.1 - 2.2e-05 24.2 1.0 0.00014 21.6 0.0 2.6 2 1 1 3 3 3 1 Variant SH3 domain Herpes_gE PF02480.16 KXS09295.1 - 0.00022 20.1 0.2 0.00033 19.6 0.2 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E SH3_1 PF00018.28 KXS09295.1 - 0.0013 18.3 0.0 0.0013 18.3 0.0 1.6 2 0 0 2 2 2 1 SH3 domain TMEM154 PF15102.6 KXS09295.1 - 0.16 11.8 7.2 0.54 10.2 7.2 1.8 1 1 0 1 1 1 0 TMEM154 protein family SH3_2 PF07653.17 KXS09295.1 - 0.17 11.6 0.0 0.45 10.2 0.0 1.7 1 0 0 1 1 1 0 Variant SH3 domain DUF5305 PF17231.2 KXS09295.1 - 0.17 11.2 1.7 0.33 10.3 1.7 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF5305) UCH PF00443.29 KXS09299.1 - 1.2e-59 201.9 0.0 1.6e-59 201.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KXS09299.1 - 8.2e-17 61.8 0.0 6.9e-08 32.4 0.0 3.2 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase CS PF04969.16 KXS09299.1 - 0.0046 18.0 0.0 0.013 16.6 0.0 1.8 1 0 0 1 1 1 1 CS domain ADH_zinc_N_2 PF13602.6 KXS09300.1 - 4.5e-24 86.0 0.0 8.7e-24 85.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KXS09300.1 - 1.4e-23 83.3 0.1 2.3e-23 82.6 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXS09300.1 - 2.8e-08 33.6 0.6 1.3e-07 31.4 0.1 2.3 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 KXS09300.1 - 0.0026 17.6 0.3 0.0063 16.4 0.0 1.7 2 0 0 2 2 2 1 N-terminal domain of oxidoreductase DapB_N PF01113.20 KXS09300.1 - 0.077 13.1 0.1 0.14 12.3 0.1 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus ssDBP_DBD PF18361.1 KXS09300.1 - 0.16 12.1 0.0 0.35 11.0 0.0 1.5 1 0 0 1 1 1 0 Single stranded DNA-binding protein ss DNA binding domain NFACT-R_1 PF05670.13 KXS09301.1 - 3.3e-31 108.2 0.0 6.4e-31 107.2 0.0 1.5 1 0 0 1 1 1 1 NFACT protein RNA binding domain FbpA PF05833.11 KXS09301.1 - 1.2e-30 106.7 0.2 1e-21 77.3 0.0 2.3 2 0 0 2 2 2 2 Fibronectin-binding protein A N-terminus (FbpA) NFACT-C PF11923.8 KXS09301.1 - 4.8e-28 97.2 0.1 2.4e-27 94.9 0.1 2.3 1 0 0 1 1 1 1 NFACT protein C-terminal domain zf-AN1 PF01428.16 KXS09302.1 - 1.2e-20 73.3 26.9 5.9e-13 48.7 3.5 3.2 2 1 1 3 3 3 2 AN1-like Zinc finger zf-ribbon_3 PF13248.6 KXS09302.1 - 0.022 14.2 0.4 5.4 6.6 0.0 2.6 2 0 0 2 2 2 0 zinc-ribbon domain C5HCH PF17982.1 KXS09302.1 - 4.8 7.4 19.2 9.2 6.5 1.6 3.7 2 1 1 3 3 3 0 NSD Cys-His rich domain Desmo_N PF06771.11 KXS09303.1 - 0.11 12.8 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 Viral Desmoplakin N-terminus HA2 PF04408.23 KXS09304.1 - 2.9e-19 69.3 0.0 2.9e-19 69.3 0.0 2.7 3 0 0 3 3 3 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KXS09304.1 - 2e-12 47.4 0.1 4.1e-12 46.4 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KXS09304.1 - 6.1e-09 35.9 0.0 1.1e-08 35.1 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.16 KXS09304.1 - 1.6e-05 25.2 0.0 3.9e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.6 KXS09304.1 - 0.0026 18.1 0.0 0.0067 16.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KXS09304.1 - 0.0042 16.8 0.0 0.0042 16.8 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KXS09304.1 - 0.016 15.6 0.4 0.057 13.8 0.4 1.9 1 1 0 1 1 1 0 AAA ATPase domain T2SSE PF00437.20 KXS09304.1 - 0.027 13.5 0.0 0.055 12.5 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein SRP54 PF00448.22 KXS09304.1 - 0.12 11.9 0.4 1.6 8.3 0.4 2.2 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain DUF4536 PF15055.6 KXS09305.1 - 2.1e-05 24.7 2.1 4.4e-05 23.6 2.1 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4536) DUF1266 PF06889.11 KXS09306.1 - 0.6 10.1 2.5 2.7 8.0 2.5 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1266) DUF1445 PF07286.12 KXS09307.1 - 6.8e-38 129.8 0.2 7.5e-38 129.7 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1445) ArfGap PF01412.18 KXS09308.1 - 6e-31 106.9 0.1 9.2e-31 106.3 0.1 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Adap_comp_sub PF00928.21 KXS09309.1 - 1.4e-57 195.1 0.0 1.7e-57 194.8 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KXS09309.1 - 0.00046 20.1 0.0 0.012 15.5 0.0 2.2 2 0 0 2 2 2 1 Clathrin adaptor complex small chain DUF1524 PF07510.11 KXS09310.1 - 0.13 12.2 1.1 0.15 12.0 1.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1524) zf-ANAPC11 PF12861.7 KXS09311.1 - 6.2e-43 144.8 9.5 6.8e-43 144.7 9.5 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 KXS09311.1 - 4.9e-23 81.2 11.3 6.7e-23 80.7 11.3 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KXS09311.1 - 6e-06 26.5 15.7 0.0001 22.5 15.8 2.3 1 1 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KXS09311.1 - 0.00027 20.9 8.9 0.00056 19.9 8.9 1.5 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KXS09311.1 - 0.01 15.7 11.5 0.056 13.3 11.5 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.8 KXS09311.1 - 0.014 15.2 2.2 0.021 14.6 2.2 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_2 PF13923.6 KXS09311.1 - 0.044 13.6 16.9 0.81 9.6 16.9 2.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KXS09311.1 - 0.045 13.4 13.7 0.21 11.2 13.3 2.1 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 KXS09311.1 - 0.24 11.4 13.7 8.4 6.4 14.5 2.6 1 1 1 2 2 2 0 zinc-RING finger domain zf-RING_11 PF17123.5 KXS09311.1 - 0.53 10.1 13.4 9.4 6.1 13.4 2.4 1 1 0 1 1 1 0 RING-like zinc finger FANCL_C PF11793.8 KXS09311.1 - 7.1 6.9 18.4 87 3.4 18.4 2.8 1 1 0 1 1 1 0 FANCL C-terminal domain Adap_comp_sub PF00928.21 KXS09312.1 - 2.2e-93 312.5 0.0 3.5e-93 311.8 0.0 1.3 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KXS09312.1 - 3.4e-08 33.5 1.0 5.8e-08 32.8 1.0 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 KXS09312.1 - 0.0021 17.5 0.0 0.0038 16.7 0.0 1.3 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain APG12 PF04110.13 KXS09314.1 - 2e-27 95.4 0.0 2.4e-27 95.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.16 KXS09314.1 - 0.0052 17.0 0.0 0.0058 16.8 0.0 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like WD40 PF00400.32 KXS09315.1 - 0.00015 22.5 0.1 0.00015 22.5 0.1 2.5 3 1 0 3 3 3 1 WD domain, G-beta repeat Ras PF00071.22 KXS09317.1 - 4.3e-39 133.7 0.0 5.7e-39 133.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXS09317.1 - 9.8e-21 74.2 0.0 2.2e-20 73.1 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXS09317.1 - 3.3e-06 26.7 0.0 4.5e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family DLIC PF05783.11 KXS09317.1 - 0.072 11.9 0.1 0.14 11.0 0.0 1.5 1 1 1 2 2 2 0 Dynein light intermediate chain (DLIC) MMR_HSR1 PF01926.23 KXS09317.1 - 0.076 13.1 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase Y_phosphatase2 PF03162.13 KXS09319.1 - 8e-41 139.4 0.0 9.8e-41 139.1 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 KXS09319.1 - 0.0035 17.3 0.0 0.0068 16.4 0.0 1.5 1 1 1 2 2 2 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 KXS09319.1 - 0.022 14.4 0.0 0.026 14.1 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Baculo_PEP_C PF04513.12 KXS09321.1 - 2.1 8.4 9.8 3.1 7.8 4.5 3.0 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3584 PF12128.8 KXS09321.1 - 2.3 5.6 47.0 0.95 6.9 32.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) TFIID-31kDa PF02291.15 KXS09322.1 - 5e-36 123.4 0.0 6.4e-36 123.1 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit CENP-S PF15630.6 KXS09322.1 - 3.3e-06 27.4 0.1 5.1e-06 26.8 0.1 1.3 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 KXS09322.1 - 0.015 15.4 0.0 0.022 14.9 0.0 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold Bromo_TP PF07524.13 KXS09322.1 - 0.021 14.8 0.0 0.043 13.8 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated Histone PF00125.24 KXS09322.1 - 0.035 14.5 0.1 0.051 13.9 0.1 1.3 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 DUF4690 PF15756.5 KXS09323.1 - 0.00027 21.5 2.1 0.00027 21.5 2.1 1.8 1 1 0 1 1 1 1 Small Novel Rich in Cartilage SOG2 PF10428.9 KXS09323.1 - 3.5 6.7 14.8 5.3 6.1 14.8 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein PPI_Ypi1 PF07491.11 KXS09324.1 - 2.8e-19 68.7 0.2 5.9e-19 67.7 0.2 1.5 1 0 0 1 1 1 1 Protein phosphatase inhibitor SelP_N PF04592.14 KXS09324.1 - 0.15 11.5 9.5 0.21 11.0 9.5 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Chorion_2 PF03964.15 KXS09324.1 - 9.5 7.1 14.4 24 5.8 12.4 2.3 1 1 1 2 2 2 0 Chorion family 2 F-box-like PF12937.7 KXS09325.1 - 0.0019 18.0 0.0 0.003 17.4 0.0 1.3 1 0 0 1 1 1 1 F-box-like DIT1_PvcA PF05141.12 KXS09325.1 - 0.077 12.5 0.0 0.083 12.3 0.0 1.1 1 0 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein VWA_3 PF13768.6 KXS09325.1 - 0.12 12.3 0.0 0.15 12.0 0.0 1.1 1 0 0 1 1 1 0 von Willebrand factor type A domain Trypsin PF00089.26 KXS09328.1 - 2.7e-27 96.0 3.3 3.5e-27 95.7 3.3 1.1 1 0 0 1 1 1 1 Trypsin PIF1 PF05970.14 KXS09329.1 - 3.4e-14 52.8 0.2 4.7e-14 52.3 0.2 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KXS09329.1 - 1.3e-08 34.8 0.9 2.1e-08 34.1 0.9 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KXS09329.1 - 1.1e-06 29.0 1.1 1.7e-06 28.4 1.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KXS09329.1 - 0.00012 22.5 0.3 0.00021 21.7 0.3 1.3 1 0 0 1 1 1 1 AAA ATPase domain TrwB_AAD_bind PF10412.9 KXS09329.1 - 0.0015 17.5 0.1 0.0022 17.0 0.1 1.1 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain AAA_7 PF12775.7 KXS09329.1 - 0.017 14.7 0.0 0.027 14.0 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF815 PF05673.13 KXS09329.1 - 0.02 14.1 0.1 0.032 13.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) MeaB PF03308.16 KXS09329.1 - 0.032 13.2 0.4 0.048 12.6 0.4 1.1 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_5 PF07728.14 KXS09329.1 - 0.065 13.2 0.1 0.094 12.7 0.1 1.2 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Viral_helicase1 PF01443.18 KXS09329.1 - 0.11 12.2 0.3 0.18 11.5 0.3 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Zeta_toxin PF06414.12 KXS09329.1 - 0.15 11.3 0.1 0.26 10.6 0.1 1.2 1 0 0 1 1 1 0 Zeta toxin T2SSE PF00437.20 KXS09329.1 - 0.17 10.9 0.0 0.26 10.3 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein ATPase_2 PF01637.18 KXS09329.1 - 0.18 11.7 0.0 0.26 11.1 0.0 1.1 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_22 PF13401.6 KXS09329.1 - 0.19 12.0 0.3 0.34 11.2 0.3 1.3 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KXS09329.1 - 0.19 11.6 0.4 0.29 11.0 0.4 1.3 1 0 0 1 1 1 0 NTPase Sigma54_activat PF00158.26 KXS09329.1 - 0.24 11.1 0.1 0.37 10.5 0.1 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF2075 PF09848.9 KXS09329.1 - 0.36 10.0 0.5 0.51 9.5 0.5 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) adh_short_C2 PF13561.6 KXS09330.1 - 3.6e-59 200.2 0.4 5.4e-59 199.6 0.4 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXS09330.1 - 2.2e-44 151.3 0.1 2.8e-44 150.9 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXS09330.1 - 1.7e-09 37.9 0.2 2.8e-09 37.2 0.2 1.3 1 0 0 1 1 1 1 KR domain Glyco_tran_WecB PF03808.13 KXS09330.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family Phage_holin_3_5 PF16085.5 KXS09333.1 - 0.1 12.7 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage holin Hol, superfamily III RepA1_leader PF08048.12 KXS09334.1 - 0.013 15.8 0.1 0.026 14.8 0.1 1.5 1 0 0 1 1 1 0 Tap RepA1 leader peptide PAF-AH_p_II PF03403.13 KXS09334.1 - 0.17 10.4 0.0 0.17 10.4 0.0 1.0 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Fungal_trans PF04082.18 KXS09335.1 - 1.2e-09 37.7 0.1 2e-09 36.9 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXS09335.1 - 8.5e-05 22.6 8.5 0.00016 21.7 8.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain bZIP_1 PF00170.21 KXS09337.1 - 4.7e-06 26.6 6.9 1.1e-05 25.5 6.9 1.7 1 0 0 1 1 1 1 bZIP transcription factor KASH_CCD PF14662.6 KXS09337.1 - 0.022 14.6 2.5 0.16 11.8 2.8 1.9 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH HALZ PF02183.18 KXS09337.1 - 0.11 12.7 0.8 0.39 11.0 0.8 1.9 1 0 0 1 1 1 0 Homeobox associated leucine zipper DivIC PF04977.15 KXS09337.1 - 0.36 10.6 2.7 0.4 10.5 1.0 1.8 1 1 1 2 2 2 0 Septum formation initiator bZIP_Maf PF03131.17 KXS09337.1 - 5.1 7.7 10.2 1 9.9 6.7 1.7 2 0 0 2 2 2 0 bZIP Maf transcription factor COA2 PF17051.5 KXS09338.1 - 0.044 13.8 0.2 0.079 13.0 0.2 1.5 1 0 0 1 1 1 0 Cytochrome C oxidase assembly factor 2 Orthopox_A5L PF06193.11 KXS09338.1 - 0.13 11.7 7.2 0.4 10.1 1.0 2.1 2 0 0 2 2 2 0 Orthopoxvirus A5L protein-like GyrI-like PF06445.15 KXS09340.1 - 5.1e-11 43.1 0.0 6.7e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 GyrI-like small molecule binding domain Cass2 PF14526.6 KXS09340.1 - 0.0045 17.2 0.0 0.006 16.8 0.0 1.2 1 0 0 1 1 1 1 Integron-associated effector binding protein zf-RING_2 PF13639.6 KXS09341.1 - 2e-12 47.2 6.2 2e-12 47.2 6.2 1.6 2 0 0 2 2 1 1 Ring finger domain zf-RING_11 PF17123.5 KXS09341.1 - 8.6e-11 41.4 2.7 2e-10 40.2 2.7 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KXS09341.1 - 8.5e-09 35.1 5.7 8.5e-09 35.1 5.7 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXS09341.1 - 3.9e-08 33.0 4.1 7.6e-08 32.1 4.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXS09341.1 - 4.8e-07 29.6 4.0 8.5e-07 28.8 4.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 KXS09341.1 - 3e-06 27.4 9.4 7.8e-06 26.1 9.4 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 KXS09341.1 - 8.6e-06 25.5 2.4 1.8e-05 24.5 2.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXS09341.1 - 0.00019 21.4 1.3 0.00019 21.4 1.3 2.0 1 1 1 2 2 2 1 RING-type zinc-finger Zn_ribbon_17 PF17120.5 KXS09341.1 - 0.00029 20.4 2.3 0.00059 19.4 2.3 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 KXS09341.1 - 0.00033 20.4 4.9 0.00033 20.4 4.9 1.6 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KXS09341.1 - 0.0035 17.4 4.7 0.0061 16.6 4.7 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger YdjO PF14169.6 KXS09341.1 - 0.015 15.0 4.0 2.2 8.1 0.1 2.3 2 0 0 2 2 2 0 Cold-inducible protein YdjO VitD-bind_III PF09164.10 KXS09341.1 - 0.015 15.2 0.2 0.025 14.6 0.2 1.3 1 0 0 1 1 1 0 Vitamin D binding protein, domain III zf-RING-like PF08746.11 KXS09341.1 - 0.02 15.2 3.7 0.02 15.2 3.7 1.8 2 0 0 2 2 2 0 RING-like domain PHD PF00628.29 KXS09341.1 - 0.041 13.8 4.0 0.041 13.8 4.0 1.9 2 1 0 2 2 2 0 PHD-finger Zn_Tnp_IS1595 PF12760.7 KXS09341.1 - 2 8.5 7.8 8.9 6.4 3.3 2.3 2 0 0 2 2 2 0 Transposase zinc-ribbon domain WD40 PF00400.32 KXS09342.1 - 4.3e-08 33.7 6.3 0.012 16.4 0.0 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXS09342.1 - 0.026 14.8 0.1 11 6.4 0.0 3.5 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 KXS09342.1 - 0.029 14.9 2.6 0.26 11.9 0.1 3.5 4 0 0 4 4 4 0 PQQ-like domain DEAD PF00270.29 KXS09343.1 - 1.2e-47 162.0 0.0 2.5e-47 160.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXS09343.1 - 3.7e-25 88.4 0.0 3e-24 85.5 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 KXS09343.1 - 3.4e-13 49.6 2.5 3.4e-13 49.6 2.5 2.1 2 0 0 2 2 2 1 DBP10CT (NUC160) domain ResIII PF04851.15 KXS09343.1 - 5e-05 23.4 0.0 9e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Ank PF00023.30 KXS09344.1 - 1.6e-07 31.4 0.5 2.1e-06 27.9 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 KXS09344.1 - 5.5e-07 29.4 0.1 5.2e-06 26.4 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.7 KXS09344.1 - 8.5e-07 29.5 0.0 4.1e-05 24.1 0.0 2.5 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXS09344.1 - 2.1e-05 24.7 0.2 0.00015 22.0 0.0 2.5 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXS09344.1 - 0.00046 20.7 0.3 0.016 15.8 0.0 3.4 4 1 0 4 4 4 1 Ankyrin repeats (many copies) RNase_PH_C PF03725.15 KXS09344.1 - 0.031 14.3 0.0 0.91 9.6 0.1 2.6 2 0 0 2 2 2 0 3' exoribonuclease family, domain 2 DIOX_N PF14226.6 KXS09345.1 - 6.2e-26 91.5 0.1 3.7e-25 89.0 0.0 2.1 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KXS09345.1 - 2.8e-13 50.2 0.0 5e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Kelch_6 PF13964.6 KXS09345.1 - 0.11 12.8 0.1 0.64 10.4 0.0 2.1 2 0 0 2 2 2 0 Kelch motif GCHY-1 PF02649.14 KXS09345.1 - 0.25 10.8 0.1 0.34 10.4 0.1 1.1 1 0 0 1 1 1 0 Type I GTP cyclohydrolase folE2 N6-adenineMlase PF10237.9 KXS09346.1 - 1.2e-39 135.7 0.0 1.6e-39 135.3 0.0 1.2 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase Cons_hypoth95 PF03602.15 KXS09346.1 - 0.17 11.5 0.0 0.36 10.5 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Abhydrolase_9_N PF15420.6 KXS09347.1 - 0.93 9.5 8.8 1 9.3 7.7 1.7 1 1 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus SH3_9 PF14604.6 KXS09349.1 - 4.4e-06 26.5 0.0 7.6e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXS09349.1 - 3.1e-05 23.5 0.0 5.5e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 SH3 domain HIP1_clath_bdg PF16515.5 KXS09349.1 - 0.0051 17.4 2.1 0.0051 17.4 2.1 8.3 4 1 5 9 9 9 1 Clathrin-binding domain of Huntingtin-interacting protein 1 MscS_porin PF12795.7 KXS09349.1 - 0.89 9.0 103.1 0.36 10.3 3.1 6.4 2 1 3 5 5 5 0 Mechanosensitive ion channel porin domain DUF4140 PF13600.6 KXS09349.1 - 1.5 9.3 0.0 1.5 9.3 0.0 11.2 4 2 4 9 9 9 0 N-terminal domain of unknown function (DUF4140) KLRAQ PF10205.9 KXS09349.1 - 2.1 8.6 11.6 0.57 10.4 5.3 3.3 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein ATG16 PF08614.11 KXS09349.1 - 7 6.8 105.8 0.26 11.5 7.3 6.0 1 1 4 5 5 5 0 Autophagy protein 16 (ATG16) Ank_2 PF12796.7 KXS09350.1 - 2.9e-49 165.6 12.7 1.9e-12 47.6 0.0 6.3 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXS09350.1 - 6.5e-41 138.2 6.2 5.7e-07 30.0 0.0 10.0 5 3 5 10 10 10 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXS09350.1 - 1.3e-34 114.3 4.3 0.00014 22.0 0.1 11.3 12 0 0 12 12 12 7 Ankyrin repeat Ank_5 PF13857.6 KXS09350.1 - 4.2e-32 109.8 14.9 3.1e-09 36.9 0.2 7.6 4 1 4 8 8 8 6 Ankyrin repeats (many copies) Ank PF00023.30 KXS09350.1 - 3.3e-30 103.2 15.8 0.00013 22.2 0.0 9.7 10 1 0 10 10 10 7 Ankyrin repeat Bin3 PF06859.12 KXS09351.1 - 2.3e-34 118.2 0.0 3.7e-34 117.6 0.0 1.3 1 0 0 1 1 1 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_23 PF13489.6 KXS09351.1 - 5.5e-08 32.8 0.0 9.8e-08 32.0 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXS09351.1 - 5.7e-07 30.2 0.0 0.058 14.1 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 KXS09351.1 - 2e-06 28.4 0.0 0.00093 19.9 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXS09351.1 - 2.7e-06 27.3 0.0 4.5e-05 23.3 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXS09351.1 - 3.2e-05 24.5 0.0 0.18 12.5 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain MTS PF05175.14 KXS09351.1 - 0.036 13.6 0.0 0.16 11.5 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase small domain PrmA PF06325.13 KXS09351.1 - 0.072 12.5 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_PK PF05891.12 KXS09351.1 - 0.082 12.4 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Methyltransf_2 PF00891.18 KXS09351.1 - 0.098 11.9 0.1 0.46 9.8 0.0 2.0 3 0 0 3 3 3 0 O-methyltransferase domain Utp12 PF04003.12 KXS09352.1 - 1.7e-08 34.7 0.0 2.7e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family WD40 PF00400.32 KXS09352.1 - 0.015 16.1 0.1 0.11 13.4 0.0 2.6 2 0 0 2 2 2 0 WD domain, G-beta repeat Lactamase_B PF00753.27 KXS09353.1 - 2.7e-06 27.5 0.5 6.1e-06 26.4 0.5 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KXS09353.1 - 0.012 15.2 1.6 0.012 15.2 1.6 2.1 2 1 0 2 2 2 0 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KXS09353.1 - 0.15 12.0 0.2 3.8 7.4 0.0 2.2 2 0 0 2 2 2 0 Beta-lactamase superfamily domain Chlorovi_GP_rpt PF06598.11 KXS09353.1 - 0.23 11.5 0.0 0.5 10.5 0.0 1.5 1 0 0 1 1 1 0 Chlorovirus glycoprotein repeat SRC-1 PF08832.10 KXS09354.1 - 0.083 14.0 0.0 0.15 13.2 0.0 1.4 1 0 0 1 1 1 0 Steroid receptor coactivator ADH_N_2 PF16884.5 KXS09355.1 - 1.1e-29 102.5 0.1 2.1e-29 101.6 0.0 1.5 2 0 0 2 2 2 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 KXS09355.1 - 4.2e-14 52.6 0.8 4e-13 49.5 0.0 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXS09355.1 - 2.1e-07 32.1 0.0 3.3e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PGM_PMM_I PF02878.16 KXS09357.1 - 1.1e-31 109.4 0.0 1.8e-31 108.7 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 KXS09357.1 - 1.2e-20 74.1 0.0 2.5e-20 73.0 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 KXS09357.1 - 4.2e-16 59.2 0.0 7.3e-16 58.4 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 KXS09357.1 - 8.3e-05 22.7 0.0 0.00025 21.2 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain OrfB_Zn_ribbon PF07282.11 KXS09358.1 - 0.002 18.0 4.4 0.0042 17.0 4.4 1.4 1 1 0 1 1 1 1 Putative transposase DNA-binding domain Nup54 PF13874.6 KXS09363.1 - 0.027 14.6 4.0 0.044 13.9 4.0 1.3 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 Jnk-SapK_ap_N PF09744.9 KXS09363.1 - 0.038 14.2 1.5 0.071 13.3 1.5 1.4 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Serine_rich PF08824.10 KXS09363.1 - 0.039 14.0 0.8 0.062 13.3 0.8 1.2 1 0 0 1 1 1 0 Serine rich protein interaction domain ATG16 PF08614.11 KXS09363.1 - 0.092 13.0 6.6 0.16 12.2 6.6 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Cys_Met_Meta_PP PF01053.20 KXS09364.1 - 0.24 9.9 0.1 0.36 9.3 0.1 1.1 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Shikimate_DH PF01488.20 KXS09365.1 - 0.12 12.5 0.0 0.28 11.2 0.0 1.8 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase MPC PF03650.13 KXS09368.1 - 4.3e-44 149.1 0.7 5.1e-44 148.9 0.7 1.0 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers MtN3_slv PF03083.16 KXS09368.1 - 0.037 14.0 1.1 0.055 13.5 1.1 1.3 1 1 0 1 1 1 0 Sugar efflux transporter for intercellular exchange LRR_4 PF12799.7 KXS09369.1 - 0.00033 21.0 6.1 0.002 18.5 0.5 2.9 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) SH3_1 PF00018.28 KXS09370.1 - 3.8e-05 23.2 0.0 6.5e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KXS09370.1 - 0.0014 18.4 0.0 0.003 17.4 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KXS09370.1 - 0.0029 17.3 0.0 0.0045 16.6 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SKG6 PF08693.10 KXS09371.1 - 1.5e-05 24.3 1.7 4.4e-05 22.8 1.7 1.9 1 0 0 1 1 1 1 Transmembrane alpha-helix domain LRR_4 PF12799.7 KXS09371.1 - 3.4e-05 24.1 13.5 0.00084 19.7 1.1 2.0 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) SH3_1 PF00018.28 KXS09371.1 - 0.00066 19.2 0.0 0.0012 18.5 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KXS09371.1 - 0.0016 18.3 0.0 0.0033 17.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KXS09371.1 - 0.003 17.2 0.0 0.0065 16.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain DUF202 PF02656.15 KXS09371.1 - 0.082 13.4 0.6 0.23 11.9 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF202) LRR_1 PF00560.33 KXS09371.1 - 0.25 12.0 2.9 5 8.1 2.9 2.7 1 1 0 1 1 1 0 Leucine Rich Repeat LRR_8 PF13855.6 KXS09371.1 - 0.34 10.7 2.8 1.2 9.0 2.9 1.8 1 1 0 1 1 1 0 Leucine rich repeat DUF3445 PF11927.8 KXS09372.1 - 4.5e-46 157.3 0.0 7.4e-46 156.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) HA2 PF04408.23 KXS09372.1 - 8.9e-25 87.1 0.1 2.9e-24 85.4 0.1 1.9 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KXS09372.1 - 2e-23 82.6 0.0 4.3e-23 81.5 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold S1 PF00575.23 KXS09372.1 - 2.8e-09 37.2 0.1 8.2e-09 35.7 0.1 1.9 1 1 0 1 1 1 1 S1 RNA binding domain DEAD PF00270.29 KXS09372.1 - 4.1e-05 23.4 0.0 0.0013 18.6 0.1 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KXS09372.1 - 0.00011 22.4 0.0 0.00025 21.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KXS09372.1 - 0.00017 21.4 0.1 0.00042 20.1 0.1 1.6 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 KXS09372.1 - 0.0023 17.2 0.0 0.005 16.1 0.0 1.5 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.27 KXS09372.1 - 0.011 16.2 0.2 0.81 10.2 0.1 2.9 2 1 1 3 3 3 0 ABC transporter SRP54 PF00448.22 KXS09372.1 - 0.027 14.1 0.1 0.049 13.3 0.1 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain T2SSE PF00437.20 KXS09372.1 - 0.037 13.1 0.0 0.092 11.8 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_19 PF13245.6 KXS09372.1 - 0.11 12.8 0.2 0.25 11.7 0.2 1.5 1 0 0 1 1 1 0 AAA domain SnoaL_2 PF12680.7 KXS09373.1 - 0.0034 18.0 0.0 0.006 17.2 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like domain COesterase PF00135.28 KXS09374.1 - 1.6e-51 175.8 0.1 4.3e-51 174.3 0.1 1.4 1 1 1 2 2 2 1 Carboxylesterase family 6PF2K PF01591.18 KXS09375.1 - 6.8e-52 176.0 0.0 9.1e-52 175.6 0.0 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 KXS09375.1 - 1.6e-36 125.8 0.0 7.9e-25 87.7 0.0 2.2 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 KXS09375.1 - 0.059 13.5 0.0 0.1 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain Sigma70_r4_2 PF08281.12 KXS09375.1 - 0.17 11.6 0.4 3.2 7.5 0.1 2.3 2 0 0 2 2 2 0 Sigma-70, region 4 Ribosomal_S27e PF01667.17 KXS09378.1 - 0.038 13.7 0.5 0.067 12.9 0.5 1.4 1 0 0 1 1 1 0 Ribosomal protein S27 LRR_6 PF13516.6 KXS09378.1 - 3.7 7.8 5.0 50 4.3 0.0 3.9 4 0 0 4 4 4 0 Leucine Rich repeat AMP-binding PF00501.28 KXS09379.1 - 1.1e-91 307.6 0.0 1.3e-91 307.4 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXS09379.1 - 5.6e-18 65.7 0.9 1.2e-17 64.6 0.4 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DUF2618 PF10940.8 KXS09379.1 - 0.14 12.0 0.1 0.32 10.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2618) DnaJ_C PF01556.18 KXS09380.1 - 2.7e-37 128.1 0.1 3.6e-37 127.7 0.1 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KXS09380.1 - 8.4e-28 96.3 4.9 1.3e-27 95.7 4.9 1.3 1 0 0 1 1 1 1 DnaJ domain RPT PF13446.6 KXS09380.1 - 0.0037 17.2 0.1 0.0073 16.2 0.1 1.5 1 0 0 1 1 1 1 A repeated domain in UCH-protein HMG_box PF00505.19 KXS09382.1 - 1.7e-15 57.2 0.0 3e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KXS09382.1 - 0.00022 21.7 0.0 0.00045 20.8 0.0 1.5 1 0 0 1 1 1 1 HMG-box domain MATalpha_HMGbox PF04769.12 KXS09382.1 - 0.0074 15.6 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 HMG-box Ccdc124 PF06244.12 KXS09382.1 - 0.015 15.8 0.0 0.026 15.1 0.0 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 124 /Oxs1 HMG_box PF00505.19 KXS09383.1 - 3.9e-20 72.0 0.0 5.9e-20 71.5 0.0 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KXS09383.1 - 8.3e-07 29.5 0.0 1.6e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 HMG-box domain MATalpha_HMGbox PF04769.12 KXS09383.1 - 0.0044 16.4 0.0 0.0068 15.7 0.0 1.2 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 HMG-box Pkinase PF00069.25 KXS09387.1 - 2.8e-25 89.2 0.0 8.2e-25 87.7 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS09387.1 - 1.1e-08 34.7 0.0 4.1e-06 26.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KXS09387.1 - 0.00014 21.9 0.1 0.00028 20.9 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family SR-25 PF10500.9 KXS09387.1 - 0.063 12.9 25.4 0.13 11.9 25.4 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF2722 PF10846.8 KXS09387.1 - 0.62 9.0 14.3 0.94 8.4 14.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Med19 PF10278.9 KXS09387.1 - 1.9 8.4 22.3 0.07 13.1 16.4 1.5 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 Sigma70_ner PF04546.13 KXS09387.1 - 7.7 6.3 14.7 13 5.5 14.7 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region Nitroreductase PF00881.24 KXS09388.1 - 4.2e-30 105.0 0.0 5.5e-30 104.6 0.0 1.2 1 0 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 KXS09388.1 - 2.1e-05 24.2 0.1 0.00074 19.2 0.1 2.6 2 1 0 2 2 2 1 Putative TM nitroreductase SnoaL_2 PF12680.7 KXS09389.1 - 0.0009 19.9 0.1 0.0032 18.1 0.1 2.0 1 1 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 KXS09389.1 - 0.0013 19.2 0.0 0.0023 18.3 0.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4440) Fea1 PF07692.11 KXS09389.1 - 0.031 13.3 0.0 0.037 13.1 0.0 1.1 1 0 0 1 1 1 0 Low iron-inducible periplasmic protein Lumazine_bd_2 PF12893.7 KXS09389.1 - 0.04 14.6 0.0 0.15 12.8 0.0 1.8 2 0 0 2 2 2 0 Putative lumazine-binding DUF4440 PF14534.6 KXS09391.1 - 0.00014 22.2 0.0 0.00029 21.2 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4440) SnoaL_2 PF12680.7 KXS09391.1 - 0.0073 16.9 0.0 0.024 15.3 0.0 2.0 2 1 0 2 2 2 1 SnoaL-like domain SnoaL_4 PF13577.6 KXS09391.1 - 0.053 13.7 0.0 0.13 12.4 0.0 1.7 1 1 0 1 1 1 0 SnoaL-like domain Alba PF01918.21 KXS09391.1 - 0.14 12.0 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Alba FixQ PF05545.11 KXS09396.1 - 2.3 8.2 4.4 7.3 6.6 1.1 2.3 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ Ax_dynein_light PF10211.9 KXS09398.1 - 1.4e-91 305.6 14.4 1.6e-91 305.3 14.4 1.1 1 0 0 1 1 1 1 Axonemal dynein light chain Jnk-SapK_ap_N PF09744.9 KXS09398.1 - 0.036 14.3 16.5 2 8.7 16.5 2.3 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 EMP24_GP25L PF01105.24 KXS09398.1 - 0.079 12.9 1.7 0.13 12.2 1.7 1.4 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD TSNAXIP1_N PF15739.5 KXS09398.1 - 0.22 11.9 14.5 1.2 9.5 3.3 2.3 1 1 1 2 2 2 0 Translin-associated factor X-interacting N-terminus HALZ PF02183.18 KXS09398.1 - 0.27 11.5 5.7 0.14 12.4 1.5 2.4 2 0 0 2 2 2 0 Homeobox associated leucine zipper GrpE PF01025.19 KXS09398.1 - 0.71 9.5 10.0 3.3 7.4 9.9 2.0 2 1 0 2 2 2 0 GrpE DUF4164 PF13747.6 KXS09398.1 - 0.78 10.1 10.9 1.8 8.9 4.9 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4164) UPF0242 PF06785.11 KXS09398.1 - 0.81 9.8 11.2 0.21 11.7 7.5 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus APG6_N PF17675.1 KXS09398.1 - 2 8.9 21.0 13 6.4 21.2 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF5320 PF17253.2 KXS09398.1 - 2.1 9.5 7.4 6.4 7.9 1.3 2.7 1 1 1 2 2 2 0 Family of unknown function (DUF5320) DUF724 PF05266.14 KXS09398.1 - 2.5 7.9 12.3 2.6 7.9 10.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Spc24 PF08286.11 KXS09398.1 - 2.9 8.2 10.5 5.5 7.3 8.9 2.2 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 bZIP_2 PF07716.15 KXS09398.1 - 3.4 7.8 22.6 0.84 9.8 4.8 3.4 3 0 0 3 3 3 0 Basic region leucine zipper Ku PF02735.16 KXS09399.1 - 5.4e-22 78.5 0.0 1e-21 77.6 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_PK_bind PF08785.11 KXS09399.1 - 3.9e-18 65.8 0.4 8.6e-18 64.6 0.4 1.6 1 0 0 1 1 1 1 Ku C terminal domain like Ku_C PF03730.14 KXS09399.1 - 3.8e-05 24.3 0.0 0.00014 22.5 0.0 2.0 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm QWRF PF04484.12 KXS09400.1 - 0.069 12.9 14.0 0.097 12.4 14.0 1.2 1 0 0 1 1 1 0 QWRF family ANAPC4_WD40 PF12894.7 KXS09401.1 - 1e-21 77.0 5.2 1.5e-08 34.8 0.1 5.4 2 1 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KXS09401.1 - 3.4e-18 65.7 25.7 6.5e-05 23.6 0.4 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat Ge1_WD40 PF16529.5 KXS09401.1 - 2.1e-07 30.2 0.8 0.00054 19.0 0.0 3.5 1 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KXS09401.1 - 6.4e-06 26.2 0.0 0.3 10.9 0.0 3.4 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A TFIIIC_delta PF12657.7 KXS09401.1 - 0.087 12.7 0.5 1.1 9.2 0.0 2.6 2 1 1 3 3 3 0 Transcription factor IIIC subunit delta N-term IKI3 PF04762.12 KXS09401.1 - 0.19 9.7 3.0 1.7 6.5 2.5 2.1 1 1 0 1 1 1 0 IKI3 family Sec7 PF01369.20 KXS09402.1 - 2.4e-62 209.9 0.0 4.5e-62 209.0 0.0 1.5 1 0 0 1 1 1 1 Sec7 domain DUF1981 PF09324.10 KXS09402.1 - 3.2e-29 100.6 0.6 2.8e-26 91.2 0.1 4.1 4 0 0 4 4 4 1 Domain of unknown function (DUF1981) Sec7_N PF12783.7 KXS09402.1 - 7.3e-28 97.5 0.1 2.1e-26 92.7 0.0 2.8 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DCB PF16213.5 KXS09402.1 - 9.3e-14 51.5 0.1 3.1e-08 33.5 0.3 3.4 3 0 0 3 3 3 2 Dimerisation and cyclophilin-binding domain of Mon2 Mon2_C PF16206.5 KXS09402.1 - 0.12 10.5 0.1 0.44 8.6 0.1 1.8 1 1 1 2 2 2 0 C-terminal region of Mon2 protein HEAT PF02985.22 KXS09402.1 - 0.26 11.6 3.3 1.1e+02 3.5 0.1 5.2 6 0 0 6 6 6 0 HEAT repeat zf-C2H2 PF00096.26 KXS09403.1 - 0.00084 19.7 1.7 0.0025 18.2 1.7 1.9 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KXS09403.1 - 0.0013 19.1 3.9 0.052 14.0 0.7 2.7 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KXS09403.1 - 0.018 15.8 1.7 0.049 14.5 1.7 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger zf-met PF12874.7 KXS09403.1 - 0.24 11.9 0.7 0.52 10.8 0.7 1.6 1 0 0 1 1 1 0 Zinc-finger of C2H2 type Mei5 PF10376.9 KXS09403.1 - 0.89 9.4 4.4 0.61 9.9 2.4 1.7 1 1 1 2 2 2 0 Double-strand recombination repair protein Aldedh PF00171.22 KXS09404.1 - 1.5e-149 498.5 1.2 1.7e-149 498.3 1.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LexA_DNA_bind PF01726.16 KXS09404.1 - 0.056 13.2 0.0 0.18 11.6 0.0 1.8 1 0 0 1 1 1 0 LexA DNA binding domain KfrA_N PF11740.8 KXS09404.1 - 0.11 13.2 0.2 6.1 7.6 0.0 2.5 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term CRAL_TRIO PF00650.20 KXS09405.1 - 1.6e-26 92.9 0.0 2.6e-26 92.2 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KXS09405.1 - 1.7e-06 28.1 0.1 3.5e-06 27.1 0.1 1.5 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain EMP24_GP25L PF01105.24 KXS09405.1 - 1.4e-05 25.1 0.1 2.5e-05 24.3 0.1 1.3 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Proteasome PF00227.26 KXS09405.1 - 0.052 13.0 0.0 0.096 12.2 0.0 1.3 1 0 0 1 1 1 0 Proteasome subunit Cation_ATPase_N PF00690.26 KXS09405.1 - 0.17 11.6 0.6 1.2 8.8 0.0 2.3 2 0 0 2 2 2 0 Cation transporter/ATPase, N-terminus UQ_con PF00179.26 KXS09406.1 - 3.4e-22 78.6 0.0 5.2e-22 78.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Arm PF00514.23 KXS09407.1 - 1.8e-62 205.6 26.9 2e-05 24.5 0.2 14.0 15 0 0 15 15 15 13 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 KXS09407.1 - 1.8e-16 60.3 19.3 3e-05 24.3 0.7 7.7 1 1 6 8 8 8 6 HEAT repeats V-ATPase_H_C PF11698.8 KXS09407.1 - 1.2e-08 35.1 4.3 0.86 9.7 0.1 6.5 3 1 5 8 8 8 2 V-ATPase subunit H Arm_2 PF04826.13 KXS09407.1 - 1.3e-08 34.6 6.3 0.049 13.1 0.1 5.9 3 2 3 7 7 7 2 Armadillo-like Adaptin_N PF01602.20 KXS09407.1 - 2.2e-08 33.2 2.1 0.014 14.0 0.0 3.3 2 1 1 3 3 3 3 Adaptin N terminal region Cnd1 PF12717.7 KXS09407.1 - 1.5e-07 31.6 2.1 0.23 11.5 0.1 4.5 2 2 2 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 KXS09407.1 - 5.5e-07 30.0 20.0 0.86 10.2 0.0 9.2 8 2 3 11 11 11 2 HEAT-like repeat KAP PF05804.12 KXS09407.1 - 1.6e-05 23.3 0.9 0.16 10.1 0.7 3.1 1 1 1 3 3 3 2 Kinesin-associated protein (KAP) HEAT PF02985.22 KXS09407.1 - 0.00016 21.7 21.7 0.28 11.6 0.1 8.7 9 1 1 10 10 7 1 HEAT repeat UNC45-central PF11701.8 KXS09407.1 - 0.00039 20.4 6.1 1.5 8.8 0.1 4.5 3 2 1 4 4 4 1 Myosin-binding striated muscle assembly central DUF727 PF05303.12 KXS09407.1 - 0.013 15.6 0.0 0.036 14.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF727) NopRA1 PF16201.5 KXS09407.1 - 0.022 14.3 0.0 3.4 7.2 0.0 3.6 4 0 0 4 4 4 0 Nucleolar pre-ribosomal-associated protein 1 RTP1_C1 PF10363.9 KXS09407.1 - 0.039 14.1 0.1 6.8 6.9 0.0 4.0 4 0 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 GCIP PF13324.6 KXS09407.1 - 0.071 12.7 0.1 0.22 11.1 0.1 1.8 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Proteasom_PSMB PF10508.9 KXS09407.1 - 0.087 11.3 1.9 1.4 7.4 0.0 2.9 3 1 0 3 3 3 0 Proteasome non-ATPase 26S subunit WAPL PF07814.13 KXS09407.1 - 0.12 11.1 5.2 0.19 10.5 0.1 3.4 4 1 0 4 4 4 0 Wings apart-like protein regulation of heterochromatin RICTOR_N PF14664.6 KXS09407.1 - 0.54 9.2 2.6 7.8 5.4 0.1 3.0 2 1 0 3 3 3 0 Rapamycin-insensitive companion of mTOR, N-term RasGEF_N_2 PF14663.6 KXS09407.1 - 1.5 9.3 10.6 64 4.0 0.0 6.3 5 3 2 7 7 7 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Lactamase_B_2 PF12706.7 KXS09408.1 - 1.3e-06 28.1 0.3 3.3e-06 26.8 0.3 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain DRMBL PF07522.14 KXS09408.1 - 1.5e-06 28.3 0.0 4.9e-06 26.7 0.0 1.8 1 1 0 1 1 1 1 DNA repair metallo-beta-lactamase DUF3760 PF12586.8 KXS09408.1 - 0.099 12.8 0.2 1.8 8.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3760) Sybindin PF04099.12 KXS09409.1 - 1.6e-21 76.7 0.0 2.1e-21 76.3 0.0 1.2 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 KXS09409.1 - 0.16 12.1 0.0 0.22 11.6 0.0 1.2 1 0 0 1 1 1 0 Sedlin, N-terminal conserved region Beta-lactamase PF00144.24 KXS09410.1 - 4.6e-40 137.9 0.3 1.5e-38 132.9 0.3 2.5 1 1 0 1 1 1 1 Beta-lactamase ABC1 PF03109.16 KXS09410.1 - 1.4e-33 115.6 0.6 2.9e-33 114.5 0.6 1.6 1 0 0 1 1 1 1 ABC1 family WaaY PF06176.11 KXS09410.1 - 0.00067 19.4 0.0 0.0012 18.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) TPR_12 PF13424.6 KXS09412.1 - 1.5e-15 57.2 0.1 4e-09 36.7 0.2 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 KXS09412.1 - 3.4e-14 52.0 5.7 1.3e-08 34.3 0.0 4.6 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 KXS09412.1 - 5.6e-13 47.9 1.1 1.3e-05 24.9 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat dCache_1 PF02743.18 KXS09412.1 - 7.5e-13 48.8 0.0 7e-12 45.7 0.0 2.1 2 0 0 2 2 2 1 Cache domain TPR_8 PF13181.6 KXS09412.1 - 1.1e-08 34.6 0.8 6.5e-05 22.8 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 KXS09412.1 - 9.4e-08 31.7 5.5 2.2e-06 27.4 0.3 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KXS09412.1 - 1.7e-07 30.9 0.1 0.0014 18.1 0.0 2.3 1 1 1 2 2 2 2 MalT-like TPR region TPR_7 PF13176.6 KXS09412.1 - 2.2e-06 27.3 0.5 0.00057 19.7 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 KXS09412.1 - 7.1e-06 25.6 3.2 0.0034 17.0 0.0 3.5 4 0 0 4 4 4 2 TPR repeat TPR_16 PF13432.6 KXS09412.1 - 0.00054 20.5 6.1 2 9.2 0.1 4.1 4 0 0 4 4 3 2 Tetratricopeptide repeat HAMP PF00672.25 KXS09412.1 - 0.00065 20.0 0.0 0.0017 18.7 0.0 1.7 1 0 0 1 1 1 1 HAMP domain SNAP PF14938.6 KXS09412.1 - 0.0012 18.3 0.0 0.67 9.3 0.0 2.3 1 1 1 2 2 2 2 Soluble NSF attachment protein, SNAP TPR_17 PF13431.6 KXS09412.1 - 0.0033 17.7 0.1 2.5 8.7 0.0 3.3 2 0 0 2 2 2 1 Tetratricopeptide repeat dCache_2 PF08269.11 KXS09412.1 - 0.18 11.0 0.0 0.35 10.0 0.0 1.5 1 0 0 1 1 1 0 Cache domain TPR_14 PF13428.6 KXS09412.1 - 0.2 12.5 4.8 2.7 9.0 0.0 4.0 5 0 0 5 5 4 0 Tetratricopeptide repeat VWA PF00092.28 KXS09413.1 - 3.9e-14 53.3 0.0 4.8e-14 53.0 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KXS09413.1 - 7.3e-10 39.4 0.1 3.8e-09 37.1 0.0 1.9 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 KXS09413.1 - 0.00011 21.7 0.6 0.00017 21.1 0.6 1.3 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein DUF2201 PF09967.9 KXS09413.1 - 0.0018 18.4 0.0 0.0035 17.5 0.0 1.6 1 0 0 1 1 1 1 VWA-like domain (DUF2201) VWA_3 PF13768.6 KXS09413.1 - 0.0021 18.0 0.0 0.0032 17.4 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain dCache_1 PF02743.18 KXS09415.1 - 1.3e-14 54.6 3.5 4.4e-14 52.9 2.0 2.1 2 0 0 2 2 2 1 Cache domain ATP_synth_reg PF14960.6 KXS09415.1 - 0.17 11.4 0.3 0.31 10.6 0.3 1.4 1 0 0 1 1 1 0 ATP synthase regulation Pectinesterase PF01095.19 KXS09416.1 - 7.1e-21 74.2 2.4 1.2e-14 53.8 1.5 2.0 1 1 1 2 2 2 2 Pectinesterase Pectinesterase PF01095.19 KXS09417.1 - 1.3e-50 171.8 5.0 1.7e-50 171.4 5.0 1.0 1 0 0 1 1 1 1 Pectinesterase Bac_DnaA PF00308.18 KXS09417.1 - 0.14 12.0 0.1 0.23 11.2 0.1 1.3 1 0 0 1 1 1 0 Bacterial dnaA protein Band_7 PF01145.25 KXS09418.1 - 1e-28 100.5 4.7 1.3e-28 100.2 4.7 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family LRS4 PF10422.9 KXS09418.1 - 0.052 13.1 0.2 0.075 12.6 0.2 1.2 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 TANGO2 PF05742.12 KXS09419.1 - 1.1e-40 140.3 0.0 1.5e-40 139.9 0.0 1.2 1 0 0 1 1 1 1 Transport and Golgi organisation 2 COesterase PF00135.28 KXS09420.1 - 1.3e-55 189.2 0.0 1.4e-47 162.8 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 KXS09420.1 - 5.2e-13 49.3 0.0 3.6e-05 23.7 0.2 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold Pkinase_Tyr PF07714.17 KXS09421.1 - 3.2e-70 236.4 0.0 3.7e-47 160.8 0.0 2.5 3 0 0 3 3 3 2 Protein tyrosine kinase Pkinase PF00069.25 KXS09421.1 - 1.1e-55 188.8 0.0 8e-36 123.7 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Kinase-like PF14531.6 KXS09421.1 - 5.5e-05 22.6 0.0 0.0015 18.0 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KXS09421.1 - 0.0026 17.2 0.0 0.76 9.1 0.0 2.2 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KXS09421.1 - 0.0035 17.0 0.0 0.0067 16.0 0.0 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 KXS09421.1 - 0.0035 17.3 0.0 0.024 14.5 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family SH3_2 PF07653.17 KXS09421.1 - 0.0046 16.6 0.0 0.012 15.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KXS09421.1 - 0.013 15.4 0.0 0.051 13.4 0.0 2.0 2 0 0 2 2 2 0 Variant SH3 domain SH3_1 PF00018.28 KXS09421.1 - 0.015 14.9 0.0 0.026 14.1 0.0 1.4 1 0 0 1 1 1 0 SH3 domain RecQ5 PF06959.11 KXS09422.1 - 0.034 14.1 1.0 0.048 13.6 1.0 1.2 1 0 0 1 1 1 0 RecQ helicase protein-like 5 (RecQ5) RNase_H PF00075.24 KXS09423.1 - 5.7e-21 75.2 0.0 9e-21 74.6 0.0 1.3 1 0 0 1 1 1 1 RNase H TMEM135_C_rich PF15982.5 KXS09424.1 - 6e-11 43.1 0.9 5.7e-08 33.4 0.2 2.3 2 0 0 2 2 2 2 N-terminal cysteine-rich region of Transmembrane protein 135 Tim17 PF02466.19 KXS09424.1 - 0.039 14.3 5.0 0.056 13.8 1.1 2.8 3 0 0 3 3 3 0 Tim17/Tim22/Tim23/Pmp24 family MDMPI_C PF07398.11 KXS09424.1 - 0.34 11.8 6.2 1.7 9.5 0.5 2.5 2 0 0 2 2 2 0 MDMPI C-terminal domain ApbA PF02558.16 KXS09425.1 - 4.1e-08 33.0 0.1 1.8e-07 30.9 0.0 2.1 2 1 0 2 2 2 1 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.6 KXS09425.1 - 0.00035 21.0 0.0 0.0007 20.0 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding DAO PF01266.24 KXS09425.1 - 0.0014 18.3 0.0 0.002 17.8 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXS09425.1 - 0.0067 15.7 0.1 0.011 15.0 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXS09425.1 - 0.0098 16.4 0.5 0.021 15.4 0.5 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 KXS09425.1 - 0.03 14.2 0.5 0.071 13.0 0.5 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_8 PF13450.6 KXS09425.1 - 0.037 14.2 0.3 0.072 13.3 0.3 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.20 KXS09425.1 - 0.11 12.5 0.1 0.25 11.4 0.1 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase GIDA PF01134.22 KXS09425.1 - 0.15 11.1 0.2 0.21 10.6 0.2 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A ThiF PF00899.21 KXS09425.1 - 0.19 11.1 0.1 0.39 10.0 0.1 1.5 1 0 0 1 1 1 0 ThiF family Pyr_redox_3 PF13738.6 KXS09425.1 - 0.24 10.6 0.1 0.37 10.0 0.1 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Baculo_PEP_C PF04513.12 KXS09426.1 - 5.5e-06 26.5 32.9 2.5 8.1 0.5 9.7 5 3 4 10 10 10 6 Baculovirus polyhedron envelope protein, PEP, C terminus PH PF00169.29 KXS09426.1 - 4.7e-05 23.9 0.0 0.00011 22.7 0.0 1.7 1 0 0 1 1 1 1 PH domain ApoLp-III PF07464.11 KXS09426.1 - 0.48 10.5 48.0 0.93 9.6 0.3 7.9 4 4 4 8 8 8 0 Apolipophorin-III precursor (apoLp-III) Glyco_hydro_67N PF03648.14 KXS09426.1 - 0.57 10.5 3.2 1.4 9.2 1.1 2.9 2 0 0 2 2 2 0 Glycosyl hydrolase family 67 N-terminus HALZ PF02183.18 KXS09426.1 - 0.89 9.8 6.3 6.4 7.1 0.5 3.9 3 0 0 3 3 3 0 Homeobox associated leucine zipper DASH_Dam1 PF08653.10 KXS09426.1 - 1.3 8.9 4.8 41 4.1 0.0 5.3 6 0 0 6 6 6 0 DASH complex subunit Dam1 F-box PF00646.33 KXS09428.1 - 3.4e-05 23.6 0.2 8e-05 22.4 0.2 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KXS09428.1 - 0.00026 20.8 0.4 0.00071 19.4 0.4 1.7 1 0 0 1 1 1 1 F-box-like TPR_10 PF13374.6 KXS09429.1 - 5.8e-05 22.8 2.9 0.22 11.5 0.1 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 KXS09429.1 - 0.0017 18.3 0.1 0.48 10.6 0.1 3.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 KXS09429.1 - 0.061 13.6 0.7 1.1 9.6 0.4 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.14 KXS09429.1 - 0.36 11.6 5.1 0.54 11.0 1.9 3.2 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 KXS09429.1 - 0.55 11.2 7.5 0.38 11.7 0.8 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat His_Phos_2 PF00328.22 KXS09431.1 - 2.4e-15 56.8 0.0 3.5e-14 53.0 0.0 2.2 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Cytochrom_C PF00034.21 KXS09434.1 - 8.6e-13 49.3 0.0 1.3e-12 48.6 0.0 1.3 1 1 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 KXS09434.1 - 1.2e-08 35.1 1.6 6e-08 32.9 1.6 1.9 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 KXS09434.1 - 0.0053 16.5 1.3 0.012 15.3 1.3 1.9 1 1 0 1 1 1 1 Cytochrome c-550 domain Cytochrome-c551 PF10643.9 KXS09434.1 - 0.13 11.8 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 Hep_59 PF07052.11 KXS09435.1 - 2.5e-25 89.3 0.0 7e-25 87.8 0.0 1.8 1 0 0 1 1 1 1 Hepatocellular carcinoma-associated antigen 59 Sel1 PF08238.12 KXS09436.1 - 4e-74 243.4 33.0 5.3e-09 36.5 0.3 10.4 10 0 0 10 10 10 10 Sel1 repeat GATA PF00320.27 KXS09436.1 - 4.5e-07 29.4 6.3 8.9e-07 28.4 6.3 1.5 1 0 0 1 1 1 1 GATA zinc finger TPR_16 PF13432.6 KXS09436.1 - 8.6e-05 23.1 4.9 0.15 12.8 0.1 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 KXS09436.1 - 0.01 16.4 3.1 9 7.2 0.1 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 KXS09436.1 - 0.029 14.6 0.6 25 5.4 0.0 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 KXS09436.1 - 0.089 13.1 8.4 1.1 9.6 0.0 5.9 7 1 1 8 8 8 0 Tetratricopeptide repeat TPR_10 PF13374.6 KXS09436.1 - 0.1 12.5 2.5 2.3 8.2 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Rogdi_lz PF10259.9 KXS09437.1 - 5.6e-27 94.9 0.2 1e-26 94.0 0.2 1.5 1 1 0 1 1 1 1 Rogdi leucine zipper containing protein MIS13 PF08202.11 KXS09438.1 - 5.5e-34 117.8 0.1 9.7e-34 117.0 0.1 1.3 1 0 0 1 1 1 1 Mis12-Mtw1 protein family Uds1 PF15456.6 KXS09438.1 - 0.26 11.4 0.1 0.26 11.4 0.1 2.3 2 0 0 2 2 2 0 Up-regulated During Septation DUF3367 PF11847.8 KXS09439.1 - 1 7.2 2.7 1.2 6.9 2.7 1.0 1 0 0 1 1 1 0 Alpha-(1->3)-arabinofuranosyltransferase MCM PF00493.23 KXS09440.1 - 5.6e-98 326.5 0.0 1.5e-97 325.1 0.0 1.7 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 KXS09440.1 - 1.4e-38 131.6 0.2 2.5e-38 130.8 0.2 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KXS09440.1 - 1.7e-26 92.5 2.6 3.3e-26 91.5 2.6 1.5 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KXS09440.1 - 4e-12 46.6 0.0 1.6e-11 44.7 0.0 2.1 1 0 0 1 1 1 1 MCM N-terminal domain AAA_5 PF07728.14 KXS09440.1 - 1.3e-07 31.7 0.1 1.1e-06 28.6 0.0 2.6 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 KXS09440.1 - 2.9e-07 30.1 0.0 2.9e-05 23.5 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KXS09440.1 - 0.00024 21.0 0.0 0.001 18.9 0.0 2.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KXS09440.1 - 0.0028 17.4 0.1 1.4 8.5 0.0 2.8 3 0 0 3 3 3 2 Sigma-54 interaction domain NTPase_1 PF03266.15 KXS09440.1 - 0.019 14.9 0.0 1.8 8.5 0.0 2.4 1 1 1 2 2 2 0 NTPase FANC_SAP PF18081.1 KXS09440.1 - 0.076 13.2 0.3 0.27 11.4 0.3 1.9 1 0 0 1 1 1 0 Fanconi anemia-associated nuclease SAP domain AAA_16 PF13191.6 KXS09440.1 - 0.29 11.5 0.0 0.29 11.5 0.0 3.3 2 2 0 2 2 2 0 AAA ATPase domain Coiled-coil_56 PF09813.9 KXS09441.1 - 0.0026 17.8 0.0 0.0037 17.3 0.0 1.2 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 PQ-loop PF04193.14 KXS09443.1 - 3.9e-14 52.2 4.3 1.5e-09 37.5 1.3 2.8 2 0 0 2 2 2 2 PQ loop repeat DUF4231 PF14015.6 KXS09443.1 - 0.55 10.7 5.8 0.15 12.6 1.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4231) Zip PF02535.22 KXS09443.1 - 3.4 6.8 9.5 9.5 5.3 0.3 2.2 1 1 1 2 2 2 0 ZIP Zinc transporter Glyco_hydro_67C PF07477.12 KXS09445.1 - 0.11 12.0 0.0 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 67 C-terminus Lactamase_B PF00753.27 KXS09446.1 - 7.9e-15 55.4 0.9 1.3e-14 54.7 0.4 1.6 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KXS09446.1 - 6.4e-05 22.6 0.1 0.0001 21.9 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain HDPD PF02924.14 KXS09446.1 - 0.002 18.2 0.1 0.0036 17.4 0.1 1.4 1 0 0 1 1 1 1 Bacteriophage lambda head decoration protein D LRR_4 PF12799.7 KXS09447.1 - 4.2e-16 58.8 29.1 2.2e-07 31.1 2.2 7.4 3 1 7 10 10 10 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXS09447.1 - 5.2e-11 42.1 23.7 0.0012 18.6 1.9 6.0 4 2 1 5 5 5 4 Leucine rich repeat LRR_1 PF00560.33 KXS09447.1 - 0.00046 20.3 13.1 0.44 11.3 0.4 7.7 8 0 0 8 8 8 1 Leucine Rich Repeat SH3_9 PF14604.6 KXS09447.1 - 0.00052 19.8 0.5 0.0011 18.8 0.1 1.8 2 0 0 2 2 2 1 Variant SH3 domain Pentapeptide_3 PF13576.6 KXS09447.1 - 0.019 15.1 1.4 0.048 13.8 0.1 2.4 2 0 0 2 2 2 0 Pentapeptide repeats (9 copies) LRR_6 PF13516.6 KXS09447.1 - 0.026 14.6 17.5 0.34 11.1 0.5 6.8 9 0 0 9 9 9 0 Leucine Rich repeat SH3_1 PF00018.28 KXS09447.1 - 0.043 13.4 0.0 0.1 12.2 0.0 1.6 1 0 0 1 1 1 0 SH3 domain Piwi PF02171.17 KXS09448.1 - 2.7e-51 174.6 0.2 3.9e-51 174.1 0.2 1.2 1 0 0 1 1 1 1 Piwi domain DUF4573 PF15140.6 KXS09449.1 - 0.025 14.4 2.5 0.033 14.0 2.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4573) PRMT5_TIM PF17285.2 KXS09449.1 - 0.058 12.6 0.1 0.061 12.5 0.1 1.1 1 0 0 1 1 1 0 PRMT5 TIM barrel domain PY_rept_46 PF09689.10 KXS09449.1 - 0.065 13.8 4.1 7 7.3 0.4 2.7 1 1 1 3 3 3 0 Plasmodium yoelii repeat (PY_rept_46) eIF_4G1 PF12152.8 KXS09449.1 - 0.12 12.5 3.5 1.1 9.5 1.0 2.5 1 1 1 2 2 2 0 Eukaryotic translation initiation factor 4G1 Peptidase_S8_N PF16361.5 KXS09449.1 - 0.33 11.4 7.1 0.34 11.4 1.9 2.1 1 1 1 2 2 2 0 N-terminal of Subtilase family GDPD PF03009.17 KXS09452.1 - 4.3e-13 49.6 0.0 1.1e-11 44.9 0.0 2.5 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GTP_cyclohydro2 PF00925.20 KXS09454.1 - 6.4e-58 195.0 0.0 7.8e-58 194.7 0.0 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase II adh_short PF00106.25 KXS09455.1 - 6.8e-13 48.5 0.0 1.1e-09 38.1 0.1 2.8 2 1 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 KXS09455.1 - 9.6e-06 25.6 0.4 1.7e-05 24.9 0.4 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 KXS09455.1 - 0.0026 17.4 0.0 0.0085 15.7 0.1 1.7 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KXS09455.1 - 0.024 14.1 0.1 0.038 13.5 0.1 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Pro_isomerase PF00160.21 KXS09456.1 - 1.4e-49 168.4 0.0 2.5e-49 167.6 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_1 PF00515.28 KXS09456.1 - 2.3e-11 43.0 1.9 1.3e-05 24.8 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KXS09456.1 - 2.6e-10 39.6 2.9 1.6e-05 24.6 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KXS09456.1 - 1.4e-05 25.2 0.9 0.0011 19.2 0.1 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 KXS09456.1 - 1.7e-05 24.4 0.9 0.0049 16.5 0.4 2.5 2 0 0 2 2 2 2 TPR repeat TPR_8 PF13181.6 KXS09456.1 - 5.2e-05 23.1 1.2 0.0067 16.6 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 KXS09456.1 - 0.00016 21.4 0.9 1.2 9.3 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 KXS09456.1 - 0.00041 20.4 0.2 0.0044 17.1 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 KXS09456.1 - 0.012 16.2 4.8 1.1 9.9 0.2 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KXS09456.1 - 0.042 14.7 0.8 0.46 11.4 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 KXS09456.1 - 0.24 12.1 4.3 1.1 10.1 0.0 3.5 4 0 0 4 4 3 0 Tetratricopeptide repeat Amidohydro_2 PF04909.14 KXS09457.1 - 2.3e-32 112.9 0.0 4e-32 112.2 0.0 1.4 1 1 0 1 1 1 1 Amidohydrolase TatD_DNase PF01026.21 KXS09457.1 - 0.17 11.2 0.0 3.3 7.0 0.0 2.3 2 1 0 2 2 2 0 TatD related DNase Alpha-amylase_C PF02806.18 KXS09461.1 - 6.3e-18 65.0 0.0 1.3e-17 64.1 0.0 1.5 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Pkinase PF00069.25 KXS09462.1 - 7.1e-10 38.7 0.0 1.7e-09 37.5 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS09462.1 - 0.0081 15.5 0.0 0.014 14.7 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase D-ser_dehydrat PF14031.6 KXS09466.1 - 9.1e-14 51.9 0.1 2.1e-13 50.7 0.1 1.7 1 0 0 1 1 1 1 Putative serine dehydratase domain Ala_racemase_N PF01168.20 KXS09466.1 - 7.2e-12 45.4 1.5 3.1e-11 43.3 0.1 2.1 2 0 0 2 2 2 1 Alanine racemase, N-terminal domain ABC_tran PF00005.27 KXS09467.1 - 1.7e-29 103.1 0.0 2.8e-29 102.4 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 KXS09467.1 - 4.4e-18 65.5 23.8 5.8e-18 65.1 23.8 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 KXS09467.1 - 3.2e-13 50.2 0.8 1.4e-07 31.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KXS09467.1 - 3.9e-05 23.2 0.1 0.0059 16.1 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain Mg_chelatase PF01078.21 KXS09467.1 - 0.00035 20.0 0.2 0.00075 18.9 0.2 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_15 PF13175.6 KXS09467.1 - 0.0029 17.4 0.1 0.23 11.1 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 KXS09467.1 - 0.011 16.2 0.3 0.019 15.5 0.3 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KXS09467.1 - 0.036 13.8 0.2 0.21 11.3 0.1 2.0 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KXS09467.1 - 0.042 13.6 0.3 0.086 12.6 0.3 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain SbcCD_C PF13558.6 KXS09467.1 - 0.098 12.9 0.2 1.9 8.8 0.0 2.8 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Pkinase_Tyr PF07714.17 KXS09468.1 - 7e-31 107.4 0.0 1.6e-30 106.3 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 KXS09468.1 - 3.3e-27 95.5 0.0 6.5e-27 94.5 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Kinase-like PF14531.6 KXS09468.1 - 0.0043 16.4 0.0 0.008 15.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KXS09468.1 - 0.017 14.4 0.0 0.072 12.4 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Fzo_mitofusin PF04799.13 KXS09468.1 - 0.11 12.1 1.0 0.23 11.0 1.0 1.5 1 0 0 1 1 1 0 fzo-like conserved region Peptidase_M16_M PF16187.5 KXS09469.1 - 3.9e-78 262.6 3.0 9.3e-78 261.3 0.3 2.1 2 0 0 2 2 2 1 Middle or third domain of peptidase_M16 Peptidase_M16_C PF05193.21 KXS09469.1 - 1.9e-43 148.6 0.0 2.3e-25 89.7 0.0 3.3 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KXS09469.1 - 2e-35 122.0 0.3 6.6e-35 120.3 0.0 2.0 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) zf-MIZ PF02891.20 KXS09471.1 - 5e-09 35.8 0.0 8.6e-09 35.0 0.0 1.3 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger TSC22 PF01166.18 KXS09471.1 - 0.022 15.0 0.1 0.074 13.4 0.0 1.9 2 0 0 2 2 2 0 TSC-22/dip/bun family zf-Nse PF11789.8 KXS09471.1 - 0.032 14.0 0.0 0.07 13.0 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit F-box PF00646.33 KXS09472.1 - 0.014 15.2 0.2 0.028 14.3 0.2 1.4 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.7 KXS09472.1 - 0.2 11.6 1.2 0.24 11.3 0.1 1.6 2 0 0 2 2 2 0 F-box-like DUF4698 PF15769.5 KXS09473.1 - 0.65 9.0 1.2 1.1 8.3 1.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4698) GST_N_3 PF13417.6 KXS09476.1 - 2.4e-13 50.3 0.0 4.5e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KXS09476.1 - 1.3e-08 35.0 0.0 2.8e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KXS09476.1 - 1.2e-06 28.8 0.0 2.3e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_5 PF16865.5 KXS09476.1 - 2.7e-05 24.7 0.0 7e-05 23.4 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KXS09476.1 - 0.00016 21.6 0.1 0.00031 20.7 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KXS09476.1 - 0.00056 20.1 0.0 0.0045 17.2 0.0 2.3 2 1 1 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KXS09476.1 - 0.029 14.6 0.0 0.058 13.6 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Pkinase PF00069.25 KXS09477.1 - 1.8e-39 135.7 0.0 2.8e-39 135.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS09477.1 - 6.3e-37 127.3 0.0 1e-36 126.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ank PF00023.30 KXS09477.1 - 0.005 17.2 1.4 0.14 12.7 0.1 3.7 6 0 0 6 6 6 1 Ankyrin repeat APH PF01636.23 KXS09477.1 - 0.0083 16.1 0.0 0.02 14.8 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Ank_2 PF12796.7 KXS09477.1 - 0.017 15.7 0.0 0.11 13.1 0.0 2.2 2 1 0 2 2 2 0 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXS09477.1 - 0.02 15.4 0.0 0.073 13.7 0.0 2.0 1 1 0 1 1 1 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXS09477.1 - 0.035 14.6 0.1 0.31 11.7 0.1 2.6 2 0 0 2 2 2 0 Ankyrin repeat Pkinase_fungal PF17667.1 KXS09477.1 - 0.043 12.6 0.0 0.07 11.9 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Fungal_trans PF04082.18 KXS09478.1 - 3.1e-17 62.5 0.1 4.8e-17 61.9 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXS09478.1 - 3.5e-07 30.2 11.9 6.1e-07 29.5 11.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hydantoinase_B PF02538.14 KXS09479.1 - 2.8e-221 735.4 0.0 4.1e-221 734.9 0.0 1.2 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 KXS09479.1 - 1.5e-98 329.7 0.1 5.8e-98 327.7 0.0 2.0 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 KXS09479.1 - 8.7e-57 191.7 0.0 3.6e-55 186.4 0.0 2.4 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region MFS_1 PF07690.16 KXS09480.1 - 1.6e-34 119.4 31.6 1.6e-34 119.4 31.6 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Presenilin PF01080.17 KXS09481.1 - 7.9e-103 344.3 14.0 9e-66 222.3 4.4 2.3 3 0 0 3 3 3 2 Presenilin AAA PF00004.29 KXS09482.1 - 5.9e-38 130.3 0.0 1.2e-37 129.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KXS09482.1 - 1.6e-08 34.2 0.0 4.2e-08 32.9 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 KXS09482.1 - 2e-06 27.9 0.1 8.6e-06 25.8 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KXS09482.1 - 8.9e-06 25.5 0.0 1.9e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KXS09482.1 - 9.8e-05 22.8 0.1 0.0011 19.4 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain AAA_14 PF13173.6 KXS09482.1 - 0.00013 22.0 0.0 0.00024 21.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KXS09482.1 - 0.00018 21.8 0.4 0.0053 17.0 0.4 2.4 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KXS09482.1 - 0.00065 19.5 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_28 PF13521.6 KXS09482.1 - 0.00081 19.7 0.0 0.011 16.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 KXS09482.1 - 0.0012 18.2 0.3 0.0032 16.9 0.2 1.6 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 KXS09482.1 - 0.0012 19.0 0.0 0.0027 17.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 KXS09482.1 - 0.0013 18.9 0.0 0.0031 17.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.22 KXS09482.1 - 0.0014 19.0 0.0 0.0055 17.1 0.0 2.0 2 0 0 2 2 2 1 RNA helicase TniB PF05621.11 KXS09482.1 - 0.0027 17.1 0.7 2.2 7.6 0.0 3.0 3 1 1 4 4 3 1 Bacterial TniB protein AAA_18 PF13238.6 KXS09482.1 - 0.0029 18.1 0.0 0.0062 17.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 KXS09482.1 - 0.0033 17.0 0.5 0.054 13.1 0.1 2.4 1 1 0 2 2 2 1 AAA domain Rad17 PF03215.15 KXS09482.1 - 0.0052 16.7 0.0 0.011 15.6 0.0 1.5 1 1 0 1 1 1 1 Rad17 P-loop domain Guanylate_kin PF00625.21 KXS09482.1 - 0.007 16.1 0.1 0.11 12.2 0.0 2.7 2 1 0 3 3 3 1 Guanylate kinase AAA_7 PF12775.7 KXS09482.1 - 0.0094 15.5 0.0 0.02 14.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region Sigma54_activ_2 PF14532.6 KXS09482.1 - 0.012 15.7 0.0 0.024 14.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_24 PF13479.6 KXS09482.1 - 0.015 15.1 0.1 0.032 13.9 0.1 1.7 1 1 0 1 1 1 0 AAA domain DUF815 PF05673.13 KXS09482.1 - 0.021 14.0 0.0 0.033 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) NACHT PF05729.12 KXS09482.1 - 0.027 14.4 0.1 0.13 12.1 0.0 2.0 1 1 1 2 2 2 0 NACHT domain Sigma54_activat PF00158.26 KXS09482.1 - 0.028 14.1 0.0 0.1 12.3 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain Viral_helicase1 PF01443.18 KXS09482.1 - 0.038 13.7 0.0 0.065 13.0 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Zeta_toxin PF06414.12 KXS09482.1 - 0.042 13.1 0.1 0.087 12.1 0.1 1.4 1 0 0 1 1 1 0 Zeta toxin TsaE PF02367.17 KXS09482.1 - 0.049 13.6 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 KXS09482.1 - 0.059 13.9 0.0 0.18 12.3 0.0 1.9 2 1 0 2 2 1 0 ABC transporter AAA_17 PF13207.6 KXS09482.1 - 0.062 13.7 0.1 0.16 12.4 0.1 1.7 1 0 0 1 1 1 0 AAA domain CPT PF07931.12 KXS09482.1 - 0.071 12.9 0.5 0.3 10.9 0.0 2.1 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein TIP49 PF06068.13 KXS09482.1 - 0.095 11.9 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain ATPase PF06745.13 KXS09482.1 - 0.11 11.8 0.0 0.24 10.7 0.0 1.7 1 1 0 1 1 1 0 KaiC MCM PF00493.23 KXS09482.1 - 0.11 11.5 0.0 0.3 10.1 0.0 1.6 1 1 0 1 1 1 0 MCM P-loop domain Parvo_NS1 PF01057.17 KXS09482.1 - 0.15 11.2 0.1 0.24 10.4 0.1 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ATPase_2 PF01637.18 KXS09482.1 - 0.15 12.0 0.1 0.38 10.6 0.0 1.7 2 1 0 2 2 1 0 ATPase domain predominantly from Archaea AAA_3 PF07726.11 KXS09482.1 - 0.17 11.8 0.0 0.36 10.7 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Hydin_ADK PF17213.3 KXS09482.1 - 0.88 9.8 3.9 10 6.3 0.1 2.8 3 1 0 3 3 2 0 Hydin Adenylate kinase-like domain DUF2408 PF10303.9 KXS09485.1 - 4.1e-47 160.1 0.0 3.9e-13 50.1 0.1 5.1 2 1 3 5 5 5 5 Protein of unknown function (DUF2408) Baculo_PEP_C PF04513.12 KXS09485.1 - 0.0029 17.6 0.1 0.29 11.2 0.0 3.2 3 0 0 3 3 3 1 Baculovirus polyhedron envelope protein, PEP, C terminus MAP65_ASE1 PF03999.12 KXS09485.1 - 0.016 13.9 0.2 0.029 13.1 0.2 1.4 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) DUF1664 PF07889.12 KXS09485.1 - 0.08 13.0 10.0 2.7 8.1 0.0 4.5 5 0 0 5 5 5 0 Protein of unknown function (DUF1664) U3_assoc_6 PF08640.11 KXS09485.1 - 0.18 11.9 7.8 3.2 7.9 0.0 4.4 5 0 0 5 5 5 0 U3 small nucleolar RNA-associated protein 6 MIP-T3_C PF17749.1 KXS09485.1 - 0.36 10.8 4.3 17 5.3 0.0 3.8 4 0 0 4 4 4 0 Microtubule-binding protein MIP-T3 C-terminal region DUF3450 PF11932.8 KXS09485.1 - 1.1 8.5 5.1 3.7 6.8 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3450) YabA PF06156.13 KXS09485.1 - 7.7 7.2 5.9 31 5.3 0.3 4.0 4 1 1 5 5 5 0 Initiation control protein YabA FUSC PF04632.12 KXS09485.1 - 9 4.7 6.3 10 4.5 0.1 2.6 1 1 1 3 3 3 0 Fusaric acid resistance protein family EB1 PF03271.17 KXS09486.1 - 1.4e-08 34.8 0.0 2.5e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.31 KXS09486.1 - 0.00018 21.6 0.3 0.00029 21.0 0.3 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain FAD_binding_4 PF01565.23 KXS09487.1 - 8.2e-28 96.9 0.7 1.8e-27 95.8 0.4 1.8 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 KXS09487.1 - 0.0023 18.0 0.0 0.0023 18.0 0.0 1.8 2 0 0 2 2 2 1 Berberine and berberine like AAA_18 PF13238.6 KXS09488.1 - 1.2e-06 29.1 0.0 2e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KXS09488.1 - 2.8e-05 24.3 0.3 0.0047 17.1 0.0 2.4 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 KXS09488.1 - 0.00086 18.6 0.2 0.0059 15.9 0.0 2.0 2 0 0 2 2 2 1 Zeta toxin PRK PF00485.18 KXS09488.1 - 0.0013 18.6 0.0 0.0018 18.0 0.0 1.3 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_16 PF13191.6 KXS09488.1 - 0.0021 18.5 0.0 0.0031 17.9 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.22 KXS09488.1 - 0.0031 16.7 0.0 0.0046 16.2 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain APS_kinase PF01583.20 KXS09488.1 - 0.0044 16.9 0.0 0.007 16.3 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_17 PF13207.6 KXS09488.1 - 0.014 15.8 0.0 0.11 12.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain KTI12 PF08433.10 KXS09488.1 - 0.016 14.7 0.0 0.023 14.2 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 MeaB PF03308.16 KXS09488.1 - 0.035 13.1 0.0 0.047 12.7 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Mg_chelatase PF01078.21 KXS09488.1 - 0.036 13.5 0.0 0.048 13.0 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KXS09488.1 - 0.036 14.1 0.0 0.074 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.6 KXS09488.1 - 0.047 13.4 0.0 0.085 12.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.6 KXS09488.1 - 0.057 13.1 0.0 0.091 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KXS09488.1 - 0.062 13.2 0.0 0.088 12.7 0.0 1.2 1 0 0 1 1 1 0 NTPase AAA_28 PF13521.6 KXS09488.1 - 0.078 13.2 0.4 0.18 12.1 0.1 1.9 2 1 0 2 2 2 0 AAA domain AAA PF00004.29 KXS09488.1 - 0.079 13.4 0.0 0.14 12.6 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TetR_C_7 PF14246.6 KXS09488.1 - 0.079 13.0 0.1 15 5.7 0.0 2.3 2 0 0 2 2 2 0 AefR-like transcriptional repressor, C-terminal domain AAA_22 PF13401.6 KXS09488.1 - 0.093 13.0 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 KXS09488.1 - 0.1 11.6 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein ABC_tran PF00005.27 KXS09488.1 - 0.15 12.6 0.0 0.23 12.0 0.0 1.3 1 0 0 1 1 1 0 ABC transporter DAP3 PF10236.9 KXS09488.1 - 0.21 10.7 0.0 0.26 10.4 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 ZU5 PF00791.20 KXS09490.1 - 0.15 12.4 0.0 0.23 11.9 0.0 1.3 1 0 0 1 1 1 0 ZU5 domain NIF PF03031.18 KXS09491.1 - 2.2e-53 180.2 0.0 2.8e-53 179.9 0.0 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase ZU5 PF00791.20 KXS09494.1 - 0.15 12.4 0.0 0.23 11.9 0.0 1.3 1 0 0 1 1 1 0 ZU5 domain Pkinase PF00069.25 KXS09496.1 - 2.6e-73 246.7 0.0 3.4e-73 246.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS09496.1 - 7.2e-43 146.7 0.0 1.1e-42 146.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXS09496.1 - 1.2e-07 31.3 0.0 4.9e-07 29.4 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KXS09496.1 - 0.0037 16.7 0.1 0.0065 15.8 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KXS09496.1 - 0.03 13.9 0.1 0.43 10.2 0.0 2.1 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 KXS09496.1 - 0.035 12.9 0.0 0.066 12.0 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase YrbL-PhoP_reg PF10707.9 KXS09496.1 - 0.11 12.0 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL TFIIA PF03153.13 KXS09496.1 - 2.2 8.2 4.5 3 7.8 4.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SLX9 PF15341.6 KXS09497.1 - 2.8e-14 53.6 8.5 4.1e-14 53.1 8.5 1.3 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 CD99L2 PF12301.8 KXS09497.1 - 2.6 8.3 7.1 6.2 7.1 7.2 1.7 1 1 0 1 1 1 0 CD99 antigen like protein 2 PET117 PF15786.5 KXS09497.1 - 2.9 8.2 7.5 18 5.7 0.3 2.5 2 0 0 2 2 2 0 PET assembly of cytochrome c oxidase, mitochondrial Methyltr_RsmB-F PF01189.17 KXS09498.1 - 1.8e-75 253.0 0.0 2.6e-75 252.5 0.0 1.2 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 KXS09498.1 - 1.3e-08 35.2 0.0 5.3e-08 33.2 0.0 2.0 2 0 0 2 2 2 1 N-terminal domain of 16S rRNA methyltransferase RsmF Cons_hypoth95 PF03602.15 KXS09498.1 - 0.0045 16.7 0.0 0.0081 15.8 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 FtsJ PF01728.19 KXS09498.1 - 0.016 15.3 0.1 0.034 14.3 0.1 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_15 PF09445.10 KXS09498.1 - 0.023 14.3 0.1 0.049 13.2 0.1 1.6 1 1 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_25 PF13649.6 KXS09498.1 - 0.024 15.3 0.1 0.051 14.3 0.1 1.6 1 0 0 1 1 1 0 Methyltransferase domain DUF2431 PF10354.9 KXS09498.1 - 0.031 14.5 0.0 0.058 13.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2431) Methyltransf_31 PF13847.6 KXS09498.1 - 0.05 13.4 0.1 0.077 12.8 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 KXS09498.1 - 0.099 12.4 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF1394 PF07159.12 KXS09499.1 - 3e-100 335.4 0.0 3.3e-100 335.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1394) T3SS_needle_E PF08988.10 KXS09499.1 - 0.071 13.3 0.1 8.8 6.6 0.0 2.4 2 0 0 2 2 2 0 Type III secretion system, cytoplasmic E component of needle BORCS7 PF16088.5 KXS09500.1 - 0.0081 16.4 0.1 0.01 16.1 0.1 1.2 1 0 0 1 1 1 1 BLOC-1-related complex sub-unit 7 DUF1204 PF06721.11 KXS09500.1 - 0.11 12.0 0.1 0.15 11.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1204) F-box PF00646.33 KXS09501.1 - 0.0087 15.9 0.4 0.023 14.6 0.4 1.7 1 0 0 1 1 1 1 F-box domain Sod_Cu PF00080.20 KXS09502.1 - 3e-44 150.6 3.0 4.7e-44 150.0 3.0 1.3 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) ABC_membrane PF00664.23 KXS09504.1 - 2.3e-59 201.3 25.2 1.7e-34 119.7 4.9 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KXS09504.1 - 1.9e-45 154.7 0.0 4e-25 88.9 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KXS09504.1 - 6.3e-10 38.9 0.1 0.037 13.4 0.0 4.1 3 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KXS09504.1 - 3e-07 30.6 0.2 0.51 10.1 0.1 3.9 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 KXS09504.1 - 2.7e-05 24.2 0.2 0.083 13.0 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KXS09504.1 - 3e-05 24.0 0.8 0.039 13.8 0.3 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 KXS09504.1 - 9e-05 22.9 0.0 0.033 14.6 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 KXS09504.1 - 9.6e-05 23.0 0.0 0.33 11.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KXS09504.1 - 0.00037 20.2 0.2 0.27 11.0 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain TsaE PF02367.17 KXS09504.1 - 0.00055 19.9 0.2 0.11 12.5 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 KXS09504.1 - 0.0015 18.1 0.1 0.076 12.5 0.0 2.6 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_30 PF13604.6 KXS09504.1 - 0.0058 16.4 0.1 1 9.1 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_15 PF13175.6 KXS09504.1 - 0.0073 16.1 0.0 1.9 8.1 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.12 KXS09504.1 - 0.01 15.1 0.1 0.41 9.9 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_5 PF07728.14 KXS09504.1 - 0.017 15.1 1.4 1.4 8.9 0.1 3.5 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 KXS09504.1 - 0.017 15.5 0.0 1 9.8 0.0 2.6 2 0 0 2 2 2 0 RNA helicase IstB_IS21 PF01695.17 KXS09504.1 - 0.023 14.5 0.1 1.3 8.7 0.0 2.6 2 0 0 2 2 2 0 IstB-like ATP binding protein Dynamin_N PF00350.23 KXS09504.1 - 0.023 14.7 0.8 3.2 7.8 0.1 2.4 2 0 0 2 2 2 0 Dynamin family AAA_22 PF13401.6 KXS09504.1 - 0.026 14.8 0.4 2.7 8.2 0.1 2.9 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 KXS09504.1 - 0.03 14.6 0.5 9.7 6.4 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA PF00004.29 KXS09504.1 - 0.032 14.7 0.0 0.44 11.0 0.0 2.8 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 KXS09504.1 - 0.048 13.4 0.1 0.15 11.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KXS09504.1 - 0.059 13.1 0.1 5.6 6.6 0.0 2.8 3 0 0 3 3 2 0 AAA domain FtsX PF02687.21 KXS09504.1 - 0.067 13.7 0.2 0.067 13.7 0.2 3.7 4 1 0 4 4 1 0 FtsX-like permease family TIP49 PF06068.13 KXS09504.1 - 0.068 12.4 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_19 PF13245.6 KXS09504.1 - 0.07 13.5 0.1 0.35 11.2 0.0 2.2 3 0 0 3 3 2 0 AAA domain NACHT PF05729.12 KXS09504.1 - 0.09 12.7 0.6 4 7.3 0.0 3.0 3 0 0 3 3 3 0 NACHT domain DUF815 PF05673.13 KXS09504.1 - 0.098 11.8 0.0 4.5 6.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) cobW PF02492.19 KXS09504.1 - 0.34 10.5 2.7 0.73 9.4 0.3 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Amidase PF01425.21 KXS09505.1 - 6e-92 308.9 0.0 1.8e-91 307.3 0.0 1.7 1 1 0 1 1 1 1 Amidase Sterol-sensing PF12349.8 KXS09505.1 - 0.015 15.2 0.1 0.026 14.4 0.1 1.3 1 0 0 1 1 1 0 Sterol-sensing domain of SREBP cleavage-activation Cytochrome_P460 PF16694.5 KXS09505.1 - 0.069 13.5 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 Cytochrome P460 TTc_toxin_rep PF18807.1 KXS09505.1 - 0.14 12.0 0.1 6.5 6.7 0.0 2.4 2 0 0 2 2 2 0 Tripartite Tc toxins repeat Peptidase_S15 PF02129.18 KXS09506.1 - 6e-09 35.9 0.0 7.2e-09 35.6 0.0 1.1 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) AC_N PF16214.5 KXS09507.1 - 0.14 11.2 0.0 0.17 10.9 0.0 1.0 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region Peptidase_S15 PF02129.18 KXS09508.1 - 1.5e-08 34.6 0.0 1.8e-08 34.3 0.0 1.1 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Glyoxalase PF00903.25 KXS09509.1 - 1.2e-09 38.4 0.1 1.9e-09 37.8 0.1 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KXS09509.1 - 0.005 17.1 0.0 0.008 16.4 0.0 1.4 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily FAD_binding_3 PF01494.19 KXS09510.1 - 2e-48 165.5 0.0 2.6e-48 165.1 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KXS09510.1 - 0.011 14.9 0.0 0.017 14.3 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.14 KXS09510.1 - 0.028 13.6 0.1 0.089 12.0 0.1 1.7 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KXS09510.1 - 0.057 12.5 0.1 0.35 9.9 0.0 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein TrkA_N PF02254.18 KXS09510.1 - 0.069 13.4 0.0 0.42 10.9 0.0 2.1 2 0 0 2 2 2 0 TrkA-N domain HI0933_like PF03486.14 KXS09510.1 - 0.2 10.3 0.0 0.29 9.8 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Fungal_trans PF04082.18 KXS09511.1 - 4.7e-18 65.2 0.1 6.9e-18 64.6 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXS09511.1 - 2.8e-06 27.3 11.2 5.1e-06 26.5 11.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cyclase PF04199.13 KXS09512.1 - 1.6e-20 73.7 0.1 2.3e-20 73.2 0.1 1.3 1 0 0 1 1 1 1 Putative cyclase Rieske PF00355.26 KXS09513.1 - 5.9e-07 29.4 0.0 8.8e-07 28.8 0.0 1.3 1 1 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 KXS09513.1 - 0.0012 18.7 0.0 0.0044 16.9 0.0 1.8 2 0 0 2 2 2 1 Rieske-like [2Fe-2S] domain FAA_hydrolase PF01557.18 KXS09514.1 - 8.4e-51 172.7 0.0 1.1e-50 172.3 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 KXS09514.1 - 4e-30 104.2 0.0 9.9e-30 102.9 0.0 1.7 2 0 0 2 2 2 1 Fumarylacetoacetase N-terminal Cyclase PF04199.13 KXS09515.1 - 3.1e-22 79.3 0.1 4.2e-22 78.9 0.1 1.3 1 0 0 1 1 1 1 Putative cyclase Zn_clus PF00172.18 KXS09516.1 - 1.4e-06 28.3 11.0 2.2e-06 27.7 11.0 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HSBP1 PF06825.12 KXS09516.1 - 0.073 12.9 0.4 0.14 12.1 0.1 1.6 2 0 0 2 2 2 0 Heat shock factor binding protein 1 Fungal_trans PF04082.18 KXS09517.1 - 5e-06 25.7 0.0 6e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain FAD_binding_3 PF01494.19 KXS09518.1 - 1.7e-43 149.2 0.0 2.3e-43 148.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KXS09518.1 - 0.023 13.9 0.1 0.038 13.2 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.12 KXS09518.1 - 0.18 10.8 0.0 1.4 7.9 0.0 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KXS09518.1 - 0.29 10.3 0.7 0.7 9.1 0.2 1.9 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pkinase PF00069.25 KXS09519.1 - 2.4e-07 30.4 0.0 3e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 KXS09519.1 - 0.00015 21.2 0.0 0.00019 20.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.17 KXS09519.1 - 0.0084 15.4 0.0 0.01 15.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Yippee-Mis18 PF03226.14 KXS09520.1 - 1.5e-13 50.9 1.3 1.6e-13 50.7 1.3 1.0 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.8 KXS09520.1 - 0.00048 20.3 1.4 0.00059 20.1 1.4 1.2 1 0 0 1 1 1 1 C-terminal domain of RIG-I NapB PF03892.14 KXS09520.1 - 0.06 13.4 0.1 0.11 12.5 0.1 1.4 1 0 0 1 1 1 0 Nitrate reductase cytochrome c-type subunit (NapB) DUF678 PF05077.12 KXS09520.1 - 0.069 13.3 0.2 0.41 10.8 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF678) DUF3933 PF13069.6 KXS09520.1 - 0.1 12.4 0.1 0.23 11.3 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3933) zf-CHY PF05495.12 KXS09520.1 - 1.5 9.4 7.7 16 6.1 7.6 2.1 1 1 0 1 1 1 0 CHY zinc finger Ank_2 PF12796.7 KXS09521.1 - 2.4e-06 28.1 0.1 8.7e-06 26.2 0.1 1.9 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXS09521.1 - 0.00028 21.1 0.0 1 10.2 0.0 3.4 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 KXS09521.1 - 0.00083 19.9 0.2 0.0075 16.8 0.1 2.7 2 2 1 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXS09521.1 - 0.0022 18.2 0.6 0.46 10.9 0.1 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KXS09521.1 - 0.026 15.0 1.1 1.7 9.2 0.4 2.9 2 1 0 2 2 2 0 Ankyrin repeat LRR_4 PF12799.7 KXS09523.1 - 2.5e-10 40.4 6.4 8.1e-06 26.1 0.4 2.2 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXS09523.1 - 3.5e-05 23.5 0.3 4.9e-05 23.0 0.3 1.3 1 0 0 1 1 1 1 Leucine rich repeat LRR_6 PF13516.6 KXS09523.1 - 0.0081 16.1 0.2 0.57 10.4 0.0 2.4 2 0 0 2 2 2 1 Leucine Rich repeat RNA12 PF10443.9 KXS09523.1 - 0.041 12.6 0.0 0.044 12.5 0.0 1.0 1 0 0 1 1 1 0 RNA12 protein LRR_1 PF00560.33 KXS09523.1 - 0.044 14.3 0.0 1.2 10.0 0.0 2.5 2 0 0 2 2 2 0 Leucine Rich Repeat Syndecan PF01034.20 KXS09524.1 - 0.11 12.5 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Syndecan domain CUB PF00431.20 KXS09525.1 - 2.2e-17 63.4 0.0 4.5e-17 62.4 0.0 1.4 1 0 0 1 1 1 1 CUB domain Kelch_4 PF13418.6 KXS09525.1 - 2.1e-12 46.8 13.4 0.00043 20.2 0.0 6.5 5 1 1 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.6 KXS09525.1 - 4.5e-10 39.3 4.7 0.059 13.4 0.0 5.8 6 0 0 6 6 6 2 Kelch motif Kelch_6 PF13964.6 KXS09525.1 - 1.6e-08 34.5 8.1 0.016 15.5 0.0 5.9 6 0 0 6 6 6 3 Kelch motif Kelch_1 PF01344.25 KXS09525.1 - 4.5e-05 22.9 2.6 5.8 6.6 0.1 5.5 5 0 0 5 5 5 2 Kelch motif Kelch_3 PF13415.6 KXS09525.1 - 5.1e-05 23.4 24.1 0.0021 18.3 0.1 6.6 6 2 1 7 7 7 2 Galactose oxidase, central domain Kelch_2 PF07646.15 KXS09525.1 - 0.009 16.0 2.9 2 8.5 0.0 4.2 4 0 0 4 4 4 1 Kelch motif DUF637 PF04830.13 KXS09526.1 - 0.066 13.0 0.7 0.075 12.8 0.1 1.5 2 0 0 2 2 2 0 Possible hemagglutinin (DUF637) CUE PF02845.16 KXS09528.1 - 8.8e-10 38.1 0.0 1.3e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 CUE domain TMEM171 PF15471.6 KXS09528.1 - 0.12 11.4 0.8 0.15 11.1 0.8 1.2 1 0 0 1 1 1 0 Transmembrane protein family 171 SR-25 PF10500.9 KXS09528.1 - 0.29 10.7 7.0 0.45 10.1 7.0 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein AAA_6 PF12774.7 KXS09529.1 - 3.4e-164 545.5 0.0 2.5e-161 536.1 0.0 2.7 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 KXS09529.1 - 1.3e-142 475.6 0.8 1.3e-142 475.6 0.8 3.1 3 0 0 3 3 2 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 KXS09529.1 - 1.4e-106 355.6 0.0 3.6e-106 354.2 0.0 1.8 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 KXS09529.1 - 3.5e-106 354.9 0.0 2.1e-101 339.2 0.0 2.9 2 0 0 2 2 2 2 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 KXS09529.1 - 8e-93 309.6 2.9 3e-92 307.7 0.3 3.1 3 0 0 3 3 3 1 ATP-binding dynein motor region AAA_7 PF12775.7 KXS09529.1 - 4.9e-79 264.1 0.0 3.9e-72 241.6 0.0 4.4 4 0 0 4 4 4 3 P-loop containing dynein motor region MT PF12777.7 KXS09529.1 - 8.2e-57 192.8 15.3 2e-56 191.5 15.3 1.6 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_lid_11 PF18198.1 KXS09529.1 - 8.2e-57 191.6 0.1 4.1e-55 186.1 0.0 3.0 3 0 0 3 3 3 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 KXS09529.1 - 3.2e-43 146.6 0.0 8.2e-41 138.8 0.0 3.6 3 0 0 3 3 3 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 KXS09529.1 - 1.7e-28 99.2 2.2 9.8e-28 96.8 0.1 3.4 3 0 0 3 3 2 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 KXS09529.1 - 2.3e-21 76.2 0.0 1.7e-06 28.1 0.0 5.4 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 KXS09529.1 - 1.9e-19 69.7 0.1 8.8e-19 67.6 0.1 2.2 1 0 0 1 1 1 1 AAA+ lid domain AAA PF00004.29 KXS09529.1 - 1.7e-12 47.9 0.1 0.027 14.9 0.0 4.9 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KXS09529.1 - 4.1e-11 43.5 4.6 0.0022 18.4 0.0 6.1 5 1 1 6 6 5 2 AAA ATPase domain AAA_22 PF13401.6 KXS09529.1 - 2.5e-08 34.3 1.2 0.37 11.0 0.0 5.2 4 0 0 4 4 4 1 AAA domain AAA_18 PF13238.6 KXS09529.1 - 3.9e-07 30.7 0.6 0.15 12.6 0.0 4.7 5 0 0 5 5 3 1 AAA domain RNA_helicase PF00910.22 KXS09529.1 - 9.4e-06 26.0 0.1 2.1 8.7 0.0 4.1 3 0 0 3 3 3 1 RNA helicase T2SSE PF00437.20 KXS09529.1 - 1.6e-05 24.2 0.3 0.97 8.4 0.0 3.8 4 0 0 4 4 3 2 Type II/IV secretion system protein Sigma54_activat PF00158.26 KXS09529.1 - 8.1e-05 22.4 0.3 0.29 10.8 0.0 3.9 4 0 0 4 4 4 1 Sigma-54 interaction domain AAA_14 PF13173.6 KXS09529.1 - 0.00018 21.6 2.5 0.52 10.3 0.0 4.4 5 0 0 5 5 3 1 AAA domain AAA_30 PF13604.6 KXS09529.1 - 0.00021 21.0 2.7 1.2 8.9 0.1 4.7 4 0 0 4 4 4 1 AAA domain Spc7 PF08317.11 KXS09529.1 - 0.00026 20.0 23.3 0.00027 19.9 4.5 3.9 3 0 0 3 3 3 1 Spc7 kinetochore protein TsaE PF02367.17 KXS09529.1 - 0.00054 20.0 1.9 3.7 7.5 0.0 4.1 4 0 0 4 4 4 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 KXS09529.1 - 0.00059 19.1 0.1 0.29 10.3 0.0 3.2 3 0 0 3 3 3 1 Protein of unknown function (DUF815) AAA_33 PF13671.6 KXS09529.1 - 0.00071 19.7 0.1 15 5.7 0.0 4.6 4 0 0 4 4 4 0 AAA domain Mg_chelatase PF01078.21 KXS09529.1 - 0.0029 17.0 1.5 0.89 8.9 0.0 3.3 4 0 0 4 4 3 1 Magnesium chelatase, subunit ChlI Rad17 PF03215.15 KXS09529.1 - 0.0039 17.1 0.1 14 5.6 0.0 3.6 3 0 0 3 3 3 0 Rad17 P-loop domain RsgA_GTPase PF03193.16 KXS09529.1 - 0.0054 16.6 0.1 0.5 10.3 0.0 3.3 3 0 0 3 3 3 1 RsgA GTPase SRP54 PF00448.22 KXS09529.1 - 0.0081 15.8 2.8 1.1 8.8 0.2 3.8 4 0 0 4 4 4 1 SRP54-type protein, GTPase domain NACHT PF05729.12 KXS09529.1 - 0.01 15.8 1.0 7 6.5 0.0 3.7 3 0 0 3 3 3 0 NACHT domain AAA_29 PF13555.6 KXS09529.1 - 0.011 15.4 2.3 2.2 8.1 0.1 3.5 3 0 0 3 3 3 0 P-loop containing region of AAA domain ABC_tran PF00005.27 KXS09529.1 - 0.043 14.3 4.6 23 5.5 0.1 4.3 4 0 0 4 4 3 0 ABC transporter NB-ARC PF00931.22 KXS09529.1 - 0.046 12.9 0.4 0.48 9.6 0.0 2.8 3 0 0 3 3 3 0 NB-ARC domain AAA_25 PF13481.6 KXS09529.1 - 0.047 13.3 0.8 2 8.0 0.0 3.5 3 0 0 3 3 3 0 AAA domain Tim44 PF04280.15 KXS09529.1 - 0.095 12.8 0.3 0.52 10.4 0.2 2.3 2 0 0 2 2 1 0 Tim44-like domain DUF4407 PF14362.6 KXS09529.1 - 0.18 11.1 12.0 0.23 10.7 3.8 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Zeta_toxin PF06414.12 KXS09529.1 - 0.21 10.8 2.4 3.9 6.7 0.0 3.4 4 0 0 4 4 3 0 Zeta toxin Exonuc_VII_L PF02601.15 KXS09529.1 - 0.32 10.5 8.2 0.35 10.4 1.9 2.8 2 0 0 2 2 2 0 Exonuclease VII, large subunit DUF1664 PF07889.12 KXS09529.1 - 0.32 11.0 7.6 0.31 11.1 1.7 3.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) TrwB_AAD_bind PF10412.9 KXS09529.1 - 0.47 9.3 6.1 3.4 6.5 0.0 3.9 4 0 0 4 4 4 0 Type IV secretion-system coupling protein DNA-binding domain TACC_C PF05010.14 KXS09529.1 - 0.51 10.1 15.3 0.094 12.5 3.1 3.0 2 0 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal NTPase_1 PF03266.15 KXS09529.1 - 1 9.2 3.7 12 5.7 0.0 4.0 5 0 0 5 5 3 0 NTPase Ntox28 PF15605.6 KXS09529.1 - 1.1 9.5 3.1 4.8 7.5 1.5 2.9 2 0 0 2 2 2 0 Bacterial toxin 28 AAA_13 PF13166.6 KXS09529.1 - 2.8 6.5 8.1 0.9 8.1 2.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KXS09529.1 - 3 8.1 10.3 27 5.0 0.1 4.8 5 0 0 5 5 4 0 AAA domain Atg14 PF10186.9 KXS09529.1 - 5.2 6.1 11.4 1.7 7.6 5.0 2.5 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Laminin_II PF06009.12 KXS09529.1 - 6.2 6.8 16.3 6.1 6.9 4.5 3.7 4 0 0 4 4 2 0 Laminin Domain II Sec2p PF06428.11 KXS09529.1 - 6.3 6.8 10.8 0.55 10.2 3.0 3.1 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p Filament PF00038.21 KXS09529.1 - 7.6 6.0 18.6 1.7 8.2 5.4 3.4 3 0 0 3 3 3 0 Intermediate filament protein OmpH PF03938.14 KXS09529.1 - 8.8 6.7 23.8 6 7.2 10.1 3.4 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) AA_permease_2 PF13520.6 KXS09530.1 - 4.5e-06 25.8 0.3 8.3e-06 24.9 0.2 1.4 1 1 1 2 2 2 1 Amino acid permease Lipoprotein_15 PF03640.15 KXS09530.1 - 0.1 12.2 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 Secreted repeat of unknown function DUF2236 PF09995.9 KXS09532.1 - 9.9e-25 88.1 0.0 1.8e-24 87.2 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) NUDIX PF00293.28 KXS09533.1 - 5.5e-15 55.6 0.0 8e-15 55.0 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Endonuclease_5 PF04493.14 KXS09533.1 - 0.081 12.6 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Endonuclease V UCH PF00443.29 KXS09536.1 - 5.2e-40 137.6 0.0 8.1e-40 136.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KXS09536.1 - 4.2e-24 85.7 0.0 1.9e-23 83.5 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase LysM PF01476.20 KXS09538.1 - 4.6e-05 23.4 0.0 8.2e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 LysM domain AMP-binding PF00501.28 KXS09539.1 - 9.4e-81 271.6 0.0 1.4e-80 271.0 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXS09539.1 - 9.9e-09 36.1 0.3 2.3e-08 34.9 0.3 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Ank_2 PF12796.7 KXS09541.1 - 3.8e-11 43.4 0.0 2.6e-08 34.3 0.1 2.3 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KXS09541.1 - 4.2e-08 33.3 0.6 0.031 14.7 1.3 3.6 3 1 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 KXS09541.1 - 9.7e-08 32.4 0.2 0.074 13.7 0.0 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXS09541.1 - 2.3e-06 27.5 0.2 0.77 10.5 0.0 4.2 4 1 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 KXS09541.1 - 3e-05 24.2 0.3 0.22 11.9 0.1 3.6 1 1 2 3 3 3 2 Ankyrin repeats (many copies) ELMO_CED12 PF04727.13 KXS09542.1 - 4.7e-18 65.9 0.0 1e-17 64.8 0.0 1.5 1 1 0 1 1 1 1 ELMO/CED-12 family ApbA_C PF08546.11 KXS09542.1 - 2.1e-17 63.5 0.0 4.8e-17 62.3 0.0 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 KXS09542.1 - 8.9e-15 54.6 0.0 1.7e-14 53.7 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA DUF3361 PF11841.8 KXS09542.1 - 3.5e-13 49.8 0.0 8.3e-13 48.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3361) PH_12 PF16457.5 KXS09542.1 - 5.2e-13 49.7 0.4 1.6e-12 48.1 0.0 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain adh_short_C2 PF13561.6 KXS09543.1 - 1.8e-48 165.2 0.0 2.2e-48 164.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXS09543.1 - 1.6e-44 151.7 0.0 2.1e-44 151.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXS09543.1 - 8.4e-08 32.3 0.0 1.3e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXS09543.1 - 0.0028 17.2 0.0 0.016 14.7 0.0 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Antimicrobial10 PF08105.11 KXS09543.1 - 0.098 12.8 0.1 0.26 11.4 0.1 1.6 1 0 0 1 1 1 0 Metchnikowin family Usp PF00582.26 KXS09545.1 - 5.2e-20 72.4 0.1 5.6e-20 72.3 0.1 1.1 1 0 0 1 1 1 1 Universal stress protein family AAA_26 PF13500.6 KXS09545.1 - 0.0024 17.7 0.6 1.8 8.4 0.0 2.3 1 1 1 2 2 2 2 AAA domain PK_C PF02887.16 KXS09545.1 - 0.094 12.9 0.8 3 8.1 0.1 2.4 2 0 0 2 2 2 0 Pyruvate kinase, alpha/beta domain ThrE PF06738.12 KXS09546.1 - 1.5e-59 201.3 20.4 1.3e-49 168.8 3.2 2.1 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 KXS09546.1 - 7e-15 55.3 26.2 5.9e-11 42.6 5.8 2.6 3 0 0 3 3 3 2 Threonine/Serine exporter, ThrE RTA1 PF04479.13 KXS09547.1 - 1.6e-63 214.1 11.2 5.3e-48 163.4 8.5 2.5 2 0 0 2 2 2 2 RTA1 like protein RTA1 PF04479.13 KXS09549.1 - 6.7e-55 185.9 10.7 9.9e-55 185.3 10.7 1.2 1 0 0 1 1 1 1 RTA1 like protein PIRT PF15099.6 KXS09549.1 - 0.38 10.3 2.1 0.7 9.5 0.9 2.1 2 1 0 2 2 2 0 Phosphoinositide-interacting protein family KilA-N PF04383.13 KXS09552.1 - 1.2e-05 25.1 0.0 0.0011 18.8 0.0 2.1 1 1 0 1 1 1 1 KilA-N domain THOC7 PF05615.13 KXS09553.1 - 3.6e-13 49.9 4.1 3.6e-13 49.9 4.1 1.6 1 1 1 2 2 2 1 Tho complex subunit 7 Syntaxin-6_N PF09177.11 KXS09553.1 - 0.022 15.3 0.1 0.16 12.5 0.1 2.1 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Mt_ATP-synt_B PF05405.14 KXS09553.1 - 0.082 12.5 0.3 0.12 12.0 0.3 1.2 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) zf-C4H2 PF10146.9 KXS09553.1 - 0.12 12.7 0.0 0.14 12.4 0.0 1.2 1 0 0 1 1 1 0 Zinc finger-containing protein MMR_HSR1 PF01926.23 KXS09554.1 - 7.1e-07 29.3 0.0 2e-06 27.9 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KXS09554.1 - 4.5e-06 26.7 0.1 9e-06 25.7 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase AIG1 PF04548.16 KXS09554.1 - 2.1e-05 24.0 0.0 3.4e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 AIG1 family Septin PF00735.18 KXS09554.1 - 5e-05 22.7 0.0 0.0001 21.7 0.0 1.4 1 0 0 1 1 1 1 Septin GBP PF02263.19 KXS09554.1 - 0.00023 20.5 0.0 0.00034 20.0 0.0 1.2 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain T2SSE PF00437.20 KXS09554.1 - 0.0003 19.9 0.0 0.00055 19.1 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_16 PF13191.6 KXS09554.1 - 0.0007 20.0 0.0 0.0015 18.9 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain Dynamin_N PF00350.23 KXS09554.1 - 0.001 19.1 0.1 0.0019 18.3 0.1 1.5 1 0 0 1 1 1 1 Dynamin family ABC_tran PF00005.27 KXS09554.1 - 0.0024 18.4 0.1 0.0071 16.9 0.0 2.0 2 0 0 2 2 1 1 ABC transporter AAA_29 PF13555.6 KXS09554.1 - 0.011 15.5 0.0 0.022 14.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 KXS09554.1 - 0.011 16.0 0.0 0.027 14.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KXS09554.1 - 0.015 15.8 0.2 0.038 14.5 0.1 1.5 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 KXS09554.1 - 0.022 14.2 0.0 0.045 13.2 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein AAA_7 PF12775.7 KXS09554.1 - 0.027 14.0 0.1 0.065 12.8 0.1 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase_2 PF01637.18 KXS09554.1 - 0.071 13.0 0.0 0.17 11.8 0.0 1.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea FtsK_SpoIIIE PF01580.18 KXS09554.1 - 0.083 12.2 0.1 0.21 10.9 0.1 1.6 1 1 0 1 1 1 0 FtsK/SpoIIIE family Roc PF08477.13 KXS09554.1 - 0.096 12.9 0.4 1.1 9.5 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Bud13 PF09736.9 KXS09556.1 - 1.2e-44 152.2 4.9 1.2e-44 152.2 4.9 2.5 4 0 0 4 4 4 1 Pre-mRNA-splicing factor of RES complex SH3_9 PF14604.6 KXS09557.1 - 2.1e-08 33.9 0.8 6.9e-08 32.2 0.7 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 KXS09557.1 - 0.0019 17.7 1.1 0.0034 17.0 1.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KXS09557.1 - 0.0045 16.6 0.3 0.012 15.3 0.1 1.8 2 0 0 2 2 2 1 Variant SH3 domain BAG PF02179.16 KXS09558.1 - 2.3e-11 43.9 0.2 2.3e-11 43.9 0.2 2.3 2 0 0 2 2 2 1 BAG domain IQ PF00612.27 KXS09558.1 - 0.026 14.3 1.9 0.062 13.1 1.9 1.7 1 0 0 1 1 1 0 IQ calmodulin-binding motif M16C_assoc PF08367.11 KXS09558.1 - 0.28 10.3 3.6 0.42 9.7 3.6 1.2 1 0 0 1 1 1 0 Peptidase M16C associated MS_channel PF00924.18 KXS09559.1 - 5.8e-20 71.7 3.6 1e-19 71.0 3.6 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.32 KXS09559.1 - 0.0099 15.4 1.1 0.024 14.2 0.0 2.3 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.6 KXS09559.1 - 0.028 14.4 0.0 0.16 12.0 0.0 2.4 1 0 0 1 1 1 0 EF-hand domain EF-hand_5 PF13202.6 KXS09559.1 - 0.076 12.5 0.0 0.19 11.3 0.0 1.7 1 0 0 1 1 1 0 EF hand zf-C2H2 PF00096.26 KXS09560.1 - 6.6e-05 23.1 18.8 0.0096 16.3 1.0 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXS09560.1 - 0.0013 19.4 18.1 0.041 14.7 0.7 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger Mst1_SARAH PF11629.8 KXS09560.1 - 0.026 14.6 0.6 0.055 13.6 0.6 1.4 1 0 0 1 1 1 0 C terminal SARAH domain of Mst1 zf-H2C2_2 PF13465.6 KXS09560.1 - 0.6 10.6 8.9 7.2 7.2 0.1 3.4 3 0 0 3 3 3 0 Zinc-finger double domain ketoacyl-synt PF00109.26 KXS09561.1 - 2.3e-55 187.9 0.2 2.2e-54 184.7 0.2 2.3 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KXS09561.1 - 3.1e-29 101.4 0.4 4.8e-29 100.8 0.4 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KXS09561.1 - 7.5e-07 29.6 0.0 2.3e-06 28.0 0.0 1.8 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 KXS09561.1 - 2e-05 24.1 0.0 3.9e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.10 KXS09561.1 - 0.037 13.9 0.2 1 9.3 0.1 2.4 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III AMP-binding PF00501.28 KXS09562.1 - 1.6e-51 175.3 0.1 1.3e-49 169.0 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 KXS09562.1 - 8.4e-17 61.9 0.2 2.1e-16 60.6 0.2 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain RabGAP-TBC PF00566.18 KXS09563.1 - 0.0051 16.5 0.0 0.014 15.1 0.0 1.6 2 0 0 2 2 2 1 Rab-GTPase-TBC domain PhzC-PhzF PF02567.16 KXS09564.1 - 1e-52 179.4 0.0 1.1e-52 179.2 0.0 1.0 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Pro_racemase PF05544.11 KXS09564.1 - 3.9e-07 29.4 0.0 2.6e-05 23.5 0.0 2.2 1 1 1 2 2 2 2 Proline racemase zf-C3HC4_3 PF13920.6 KXS09565.1 - 0.021 14.7 5.4 0.042 13.7 5.4 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KXS09565.1 - 0.051 13.4 7.0 0.14 12.1 7.1 1.7 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 Ribosomal_60s PF00428.19 KXS09566.1 - 0.099 13.2 8.3 2.2 8.9 4.0 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein adh_short PF00106.25 KXS09567.1 - 3.1e-52 176.9 0.1 4.1e-52 176.5 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXS09567.1 - 5.4e-39 134.1 0.1 6.6e-39 133.8 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXS09567.1 - 5.7e-13 49.2 0.1 7.3e-13 48.8 0.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXS09567.1 - 0.00052 19.5 0.4 0.00082 18.9 0.1 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 KXS09567.1 - 0.009 15.4 0.0 0.022 14.1 0.0 1.7 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) THF_DHG_CYH_C PF02882.19 KXS09567.1 - 0.011 15.1 0.0 0.033 13.5 0.0 1.8 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_10 PF13460.6 KXS09567.1 - 0.019 14.9 0.6 0.085 12.7 0.6 1.9 1 1 0 1 1 1 0 NAD(P)H-binding Wax2_C PF12076.8 KXS09567.1 - 0.084 12.6 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 WAX2 C-terminal domain 2-Hacid_dh_C PF02826.19 KXS09567.1 - 0.099 12.0 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain adh_short PF00106.25 KXS09568.1 - 4.7e-70 235.0 21.9 4.8e-38 130.6 6.0 2.7 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXS09568.1 - 2.2e-56 191.1 14.2 1.2e-29 103.6 3.9 2.3 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXS09568.1 - 4.4e-25 88.6 12.0 2.1e-14 53.8 2.8 2.2 2 0 0 2 2 2 2 KR domain THF_DHG_CYH_C PF02882.19 KXS09568.1 - 0.0017 17.7 5.0 0.19 11.0 0.5 2.6 2 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain RNA_GG_bind PF10258.9 KXS09568.1 - 0.016 15.2 0.0 12 6.0 0.0 3.6 4 0 0 4 4 4 0 PHAX RNA-binding domain DUF2677 PF10838.8 KXS09568.1 - 0.17 11.8 0.1 0.64 10.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2677) NAD_binding_7 PF13241.6 KXS09568.1 - 0.64 10.5 5.3 13 6.3 1.1 2.7 2 0 0 2 2 2 0 Putative NAD(P)-binding 3HCDH_N PF02737.18 KXS09568.1 - 6.7 6.6 12.6 1.9 8.3 1.8 2.4 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Cupin_8 PF13621.6 KXS09570.1 - 6.7e-42 144.0 0.0 1e-41 143.3 0.0 1.3 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 KXS09570.1 - 0.00016 21.3 0.4 0.0004 19.9 0.1 1.8 3 0 0 3 3 3 1 Cupin superfamily protein JmjC PF02373.22 KXS09570.1 - 0.16 12.4 0.0 0.34 11.3 0.0 1.5 1 0 0 1 1 1 0 JmjC domain, hydroxylase BUD22 PF09073.10 KXS09570.1 - 0.22 10.8 4.9 0.32 10.3 4.9 1.1 1 0 0 1 1 1 0 BUD22 CCDC-167 PF15188.6 KXS09570.1 - 0.25 11.7 0.9 5.4 7.4 1.1 2.3 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 Nop14 PF04147.12 KXS09570.1 - 2.7 6.1 8.7 3.6 5.7 8.7 1.1 1 0 0 1 1 1 0 Nop14-like family Transglut_core PF01841.19 KXS09571.1 - 5.8e-08 33.2 0.0 1.1e-07 32.3 0.0 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF553 PF04473.12 KXS09571.1 - 0.011 15.3 0.0 0.019 14.5 0.0 1.4 1 0 0 1 1 1 0 Transglutaminase-like domain Transglut_core PF01841.19 KXS09574.1 - 3.1e-09 37.3 0.0 6.2e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF553 PF04473.12 KXS09574.1 - 0.046 13.3 0.0 7.6 6.0 0.3 3.0 2 1 0 2 2 2 0 Transglutaminase-like domain Acetyltransf_2 PF00797.17 KXS09574.1 - 0.2 11.4 0.0 0.34 10.7 0.0 1.3 1 0 0 1 1 1 0 N-acetyltransferase Pex2_Pex12 PF04757.14 KXS09575.1 - 6.6e-31 107.7 0.0 8.9e-31 107.2 0.0 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.6 KXS09575.1 - 3.3e-10 39.7 6.0 4.9e-10 39.1 6.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXS09575.1 - 1.7e-09 37.4 8.7 2.9e-09 36.6 8.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXS09575.1 - 4.1e-09 36.6 10.4 7e-09 35.9 10.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KXS09575.1 - 5.2e-09 35.8 8.9 8.7e-09 35.1 8.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KXS09575.1 - 2.7e-07 30.8 6.7 6.1e-07 29.6 6.7 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 KXS09575.1 - 3.3e-07 30.0 7.4 5.2e-07 29.4 7.4 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KXS09575.1 - 3.8e-07 30.0 7.4 6.6e-07 29.2 7.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KXS09575.1 - 8.1e-07 29.0 4.4 9.6e-06 25.5 5.3 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KXS09575.1 - 1.5e-06 28.3 9.2 2.9e-06 27.3 9.2 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 KXS09575.1 - 0.00018 21.5 2.5 0.00032 20.7 2.5 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.8 KXS09575.1 - 0.036 13.9 4.0 0.083 12.7 4.0 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.6 KXS09575.1 - 0.082 12.7 7.7 0.15 11.9 7.7 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_10 PF16685.5 KXS09575.1 - 0.15 12.2 5.2 0.3 11.2 5.2 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_6 PF14835.6 KXS09575.1 - 0.15 11.9 2.5 0.28 11.1 2.5 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Zn_ribbon_17 PF17120.5 KXS09575.1 - 0.25 11.0 5.9 0.46 10.1 5.9 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type DUF3090 PF11290.8 KXS09575.1 - 3.2 7.5 4.3 28 4.5 0.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3090) DUF572 PF04502.13 KXS09576.1 - 3.2e-82 276.8 0.7 3.9e-82 276.6 0.7 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) TF_Zn_Ribbon PF08271.12 KXS09576.1 - 0.0071 15.8 1.3 0.0071 15.8 1.3 2.4 2 0 0 2 2 2 1 TFIIB zinc-binding DUF866 PF05907.13 KXS09576.1 - 0.033 14.1 0.6 0.057 13.3 0.6 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF866) DUF2797 PF10977.8 KXS09576.1 - 0.52 10.2 3.6 0.93 9.3 3.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2797) zf-PHD-like PF15446.6 KXS09576.1 - 1.1 8.8 5.2 1.3 8.7 1.6 2.2 1 1 1 2 2 2 0 PHD/FYVE-zinc-finger like domain Pkinase PF00069.25 KXS09577.1 - 1.4e-58 198.4 0.0 8.1e-45 153.2 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXS09577.1 - 1.1e-25 90.5 0.0 1.6e-25 89.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KXS09577.1 - 4.2e-07 29.5 0.2 1.5e-06 27.8 0.3 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KXS09577.1 - 1.8e-06 27.5 0.0 7.6e-06 25.4 0.0 1.8 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 KXS09577.1 - 0.00014 21.9 0.0 0.00022 21.2 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXS09577.1 - 0.00043 19.2 0.0 0.00056 18.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 KXS09577.1 - 0.0019 17.2 0.2 0.0043 16.0 0.1 1.5 2 0 0 2 2 2 1 Haspin like kinase domain RIO1 PF01163.22 KXS09577.1 - 0.0023 17.6 0.2 0.0046 16.6 0.2 1.4 1 0 0 1 1 1 1 RIO1 family FTA2 PF13095.6 KXS09577.1 - 0.021 14.4 0.0 0.066 12.8 0.0 1.9 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DUF1556 PF07590.11 KXS09577.1 - 0.29 11.5 2.0 0.4 11.0 0.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1556) Metallophos PF00149.28 KXS09578.1 - 4.9e-10 40.2 0.0 9.9e-10 39.3 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase ADH_zinc_N PF00107.26 KXS09579.1 - 1.1e-17 64.3 0.0 1.6e-17 63.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXS09579.1 - 5.5e-12 46.9 0.0 8.4e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXS09579.1 - 5.9e-08 32.6 0.0 1.6e-07 31.2 0.0 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ACP_syn_III_C PF08541.10 KXS09579.1 - 0.0031 17.6 0.0 0.028 14.6 0.0 2.4 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Peptidase_M24 PF00557.24 KXS09580.1 - 4.3e-48 163.8 0.1 5.5e-48 163.4 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 KXS09580.1 - 3.5e-12 46.4 12.0 8.4e-12 45.2 12.0 1.5 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 KXS09580.1 - 0.00053 20.0 10.9 0.001 19.1 10.9 1.5 1 0 0 1 1 1 1 MYND finger Peptidase_M24 PF00557.24 KXS09581.1 - 3.2e-48 164.2 0.1 3.9e-48 163.9 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 KXS09581.1 - 3e-12 46.6 7.1 7.6e-12 45.3 7.1 1.7 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 KXS09581.1 - 0.039 14.0 4.5 0.039 14.0 4.5 1.9 2 0 0 2 2 2 0 MYND finger SelB-wing_1 PF09105.10 KXS09581.1 - 0.073 13.1 0.1 7 6.7 0.0 2.9 3 0 0 3 3 3 0 Elongation factor SelB, winged helix HHH_8 PF14716.6 KXS09582.1 - 2.2e-10 40.7 0.1 4.7e-10 39.7 0.1 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain Troponin-I_N PF11636.8 KXS09582.1 - 0.057 13.4 0.1 0.23 11.4 0.1 2.1 1 0 0 1 1 1 0 Troponin I residues 1-32 Ank PF00023.30 KXS09583.1 - 3.4e-30 103.2 1.4 1.1e-06 28.8 0.0 5.3 5 0 0 5 5 5 4 Ankyrin repeat Ank_2 PF12796.7 KXS09583.1 - 9.4e-26 90.2 0.0 6e-12 46.0 0.0 3.1 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXS09583.1 - 1.2e-24 83.7 0.1 1.2e-05 25.3 0.0 5.1 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 KXS09583.1 - 4.8e-23 80.9 0.2 7.7e-06 26.1 0.1 4.3 4 0 0 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXS09583.1 - 2.7e-22 78.8 0.1 3.4e-09 37.1 0.0 4.7 3 2 1 4 4 4 4 Ankyrin repeats (many copies) GDPD PF03009.17 KXS09584.1 - 8e-55 186.4 0.0 1.1e-54 185.9 0.0 1.1 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family DUF3605 PF12239.8 KXS09585.1 - 2.2e-16 60.6 1.4 3.4e-15 56.7 1.4 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF3605) Atg14 PF10186.9 KXS09586.1 - 2.5e-31 109.0 8.6 3.7e-18 65.7 0.0 2.2 2 0 0 2 2 2 2 Vacuolar sorting 38 and autophagy-related subunit 14 Plant_NMP1 PF06694.11 KXS09586.1 - 0.076 12.1 0.2 0.19 10.8 0.2 1.7 1 1 0 1 1 1 0 Plant nuclear matrix protein 1 (NMP1) IFT20 PF14931.6 KXS09586.1 - 0.097 12.9 1.0 0.18 12.0 1.0 1.3 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 DUF4337 PF14235.6 KXS09586.1 - 0.14 12.3 1.3 0.23 11.5 1.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Spc7 PF08317.11 KXS09586.1 - 0.16 10.8 3.1 0.22 10.3 3.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein SidE PF12252.8 KXS09586.1 - 0.23 9.0 1.0 0.3 8.6 1.0 1.0 1 0 0 1 1 1 0 Dot/Icm substrate protein DivIC PF04977.15 KXS09586.1 - 0.33 10.8 1.0 0.83 9.5 0.5 2.0 2 1 0 2 2 2 0 Septum formation initiator Uso1_p115_C PF04871.13 KXS09586.1 - 0.96 9.8 3.0 2.1 8.7 3.0 1.5 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Band_3_cyto PF07565.13 KXS09586.1 - 1.2 8.9 6.5 1.8 8.3 6.5 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Nup54 PF13874.6 KXS09586.1 - 1.6 8.8 7.6 3 7.9 7.6 1.4 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 dCache_2 PF08269.11 KXS09586.1 - 1.9 7.6 3.2 3 6.9 3.2 1.2 1 0 0 1 1 1 0 Cache domain CENP-H PF05837.12 KXS09586.1 - 5.2 7.5 7.4 6.1 7.3 5.8 1.8 1 1 1 2 2 2 0 Centromere protein H (CENP-H) LRS4 PF10422.9 KXS09586.1 - 8.6 5.8 8.2 31 4.0 8.2 1.8 1 1 0 1 1 1 0 Monopolin complex subunit LRS4 zf-B_box PF00643.24 KXS09586.1 - 9.4 6.5 9.2 1.7 8.9 4.8 2.0 2 0 0 2 2 2 0 B-box zinc finger NAD_kinase PF01513.21 KXS09588.1 - 1e-59 202.2 0.0 1.4e-59 201.7 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase zf-SNAP50_C PF12251.8 KXS09588.1 - 0.27 10.9 0.0 0.44 10.2 0.0 1.2 1 0 0 1 1 1 0 snRNA-activating protein of 50kDa MW C terminal Ubie_methyltran PF01209.18 KXS09589.1 - 4.5e-80 268.3 0.0 5.2e-80 268.1 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 KXS09589.1 - 1.2e-17 64.3 0.0 2.8e-17 63.2 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXS09589.1 - 1.2e-16 61.1 0.0 2.8e-16 59.9 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXS09589.1 - 2.8e-13 49.9 0.0 4.3e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXS09589.1 - 1.4e-10 41.8 0.0 2.5e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXS09589.1 - 4.5e-07 29.9 0.0 1.2e-06 28.4 0.0 1.6 1 1 1 2 2 2 1 Methyltransferase domain MTS PF05175.14 KXS09589.1 - 0.0043 16.6 0.0 0.0099 15.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_28 PF02636.17 KXS09589.1 - 0.013 15.2 0.0 0.017 14.7 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase ADH_zinc_N PF00107.26 KXS09589.1 - 0.11 12.4 0.0 0.33 10.9 0.0 1.8 2 1 0 2 2 2 0 Zinc-binding dehydrogenase Rep_fac_C PF08542.11 KXS09590.1 - 2.7e-22 79.0 0.0 1.4e-21 76.7 0.0 2.2 3 0 0 3 3 1 1 Replication factor C C-terminal domain AAA PF00004.29 KXS09590.1 - 6.4e-18 65.4 0.0 1e-17 64.8 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 KXS09590.1 - 1.4e-14 54.2 0.0 3.4e-10 39.9 0.0 2.4 1 1 1 2 2 2 2 DNA polymerase III, delta subunit Rad17 PF03215.15 KXS09590.1 - 2.4e-09 37.4 0.0 1.2e-08 35.1 0.0 1.8 1 1 1 2 2 2 1 Rad17 P-loop domain AAA_30 PF13604.6 KXS09590.1 - 5.4e-06 26.3 0.1 2.7e-05 24.0 0.0 2.1 3 0 0 3 3 2 1 AAA domain RuvB_N PF05496.12 KXS09590.1 - 1.2e-05 25.1 0.0 2.7e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_11 PF13086.6 KXS09590.1 - 1.2e-05 25.2 0.1 9.7e-05 22.3 0.0 2.0 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 KXS09590.1 - 1.9e-05 25.1 0.0 8.9e-05 22.9 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 KXS09590.1 - 2.1e-05 24.5 0.0 5.2e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_assoc_2 PF16193.5 KXS09590.1 - 3.7e-05 24.0 0.0 0.00011 22.4 0.0 1.9 1 0 0 1 1 1 1 AAA C-terminal domain AAA_22 PF13401.6 KXS09590.1 - 4.6e-05 23.7 0.2 0.021 15.1 0.0 2.6 1 1 1 2 2 2 1 AAA domain AAA_24 PF13479.6 KXS09590.1 - 0.00012 21.9 0.0 0.00028 20.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 KXS09590.1 - 0.00021 21.3 0.0 0.004 17.2 0.0 2.1 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_5 PF07728.14 KXS09590.1 - 0.00048 20.1 0.2 0.0013 18.7 0.0 1.8 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 KXS09590.1 - 0.00054 19.5 0.0 0.00093 18.8 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region DUF815 PF05673.13 KXS09590.1 - 0.00059 19.1 0.0 0.00087 18.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_19 PF13245.6 KXS09590.1 - 0.00069 20.0 0.0 0.0013 19.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain DNA_pol3_delta PF06144.13 KXS09590.1 - 0.0008 19.2 0.0 0.0012 18.7 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase III, delta subunit TniB PF05621.11 KXS09590.1 - 0.00094 18.6 0.0 0.42 10.0 0.0 2.3 1 1 1 2 2 2 1 Bacterial TniB protein AAA_3 PF07726.11 KXS09590.1 - 0.0021 17.9 0.0 0.005 16.7 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.18 KXS09590.1 - 0.0045 16.7 0.0 0.0081 15.9 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase IstB_IS21 PF01695.17 KXS09590.1 - 0.007 16.1 0.0 0.026 14.2 0.0 1.8 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_18 PF13238.6 KXS09590.1 - 0.012 16.1 0.0 0.055 14.0 0.0 2.0 2 1 0 2 2 2 0 AAA domain TPR_6 PF13174.6 KXS09590.1 - 0.017 15.7 0.7 7.6 7.4 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat AAA_28 PF13521.6 KXS09590.1 - 0.018 15.3 0.1 0.039 14.2 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KXS09590.1 - 0.026 15.0 0.4 0.065 13.7 0.4 1.9 1 1 1 2 2 1 0 AAA domain ATPase_2 PF01637.18 KXS09590.1 - 0.029 14.3 0.0 0.056 13.3 0.0 1.4 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea DEAD PF00270.29 KXS09590.1 - 0.035 13.9 0.2 0.46 10.2 0.0 2.2 1 1 1 2 2 2 0 DEAD/DEAH box helicase AAA_25 PF13481.6 KXS09590.1 - 0.036 13.6 0.1 0.14 11.7 0.1 2.0 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KXS09590.1 - 0.04 14.3 0.0 0.084 13.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_29 PF13555.6 KXS09590.1 - 0.051 13.3 0.0 0.18 11.6 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain Mg_chelatase PF01078.21 KXS09590.1 - 0.054 12.9 0.0 0.34 10.3 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 KXS09590.1 - 0.059 12.6 0.0 0.092 11.9 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain SRP54 PF00448.22 KXS09590.1 - 0.063 12.9 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain MeaB PF03308.16 KXS09590.1 - 0.095 11.7 0.1 0.87 8.5 0.0 2.0 1 1 1 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ABC_tran PF00005.27 KXS09590.1 - 0.096 13.2 0.0 0.3 11.6 0.0 2.0 1 1 0 1 1 1 0 ABC transporter AAA_33 PF13671.6 KXS09590.1 - 0.13 12.5 0.1 0.32 11.2 0.1 1.7 1 1 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 KXS09590.1 - 0.13 12.0 0.0 13 5.5 0.0 2.6 3 0 0 3 3 2 0 Sigma-54 interaction domain NTPase_1 PF03266.15 KXS09590.1 - 0.19 11.6 0.0 0.73 9.7 0.0 2.0 3 0 0 3 3 2 0 NTPase HATPase_c PF02518.26 KXS09591.1 - 6.7e-25 87.8 1.2 2.6e-24 85.9 0.1 2.4 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KXS09591.1 - 5.2e-23 81.4 0.0 3.1e-22 78.9 0.0 2.3 2 1 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 KXS09591.1 - 9.3e-11 41.6 0.2 2.1e-10 40.5 0.2 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain CBFD_NFYB_HMF PF00808.23 KXS09592.1 - 2.8e-26 91.6 0.4 4.5e-26 90.9 0.4 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KXS09592.1 - 0.00017 21.9 0.0 0.00027 21.3 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 KXS09592.1 - 0.0024 18.0 0.0 0.0037 17.4 0.0 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TFIID-18kDa PF02269.16 KXS09592.1 - 0.028 14.4 0.0 0.051 13.6 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.13 KXS09592.1 - 0.057 13.4 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Bromodomain associated Mic1 PF07035.12 KXS09593.1 - 2.6e-06 27.3 0.0 0.095 12.4 0.0 3.1 3 0 0 3 3 3 3 Colon cancer-associated protein Mic1-like Foie-gras_1 PF11817.8 KXS09595.1 - 2.5e-37 128.9 0.0 6.1e-37 127.6 0.0 1.7 1 1 0 1 1 1 1 Foie gras liver health family 1 Gryzun PF07919.12 KXS09595.1 - 2.9e-25 89.1 0.0 1.8e-24 86.5 0.0 2.1 1 1 0 1 1 1 1 Gryzun, putative trafficking through Golgi TPR_12 PF13424.6 KXS09595.1 - 0.017 15.4 1.4 0.38 11.1 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Gryzun-like PF12742.7 KXS09595.1 - 0.032 14.2 0.0 0.067 13.2 0.0 1.5 1 0 0 1 1 1 0 Gryzun, putative Golgi trafficking TRAPPC-Trs85 PF12739.7 KXS09595.1 - 0.18 10.7 0.0 0.26 10.2 0.0 1.1 1 0 0 1 1 1 0 ER-Golgi trafficking TRAPP I complex 85 kDa subunit ThiF PF00899.21 KXS09596.1 - 2.6e-65 220.2 0.0 3.6e-65 219.7 0.0 1.1 1 0 0 1 1 1 1 ThiF family E2_bind PF08825.10 KXS09596.1 - 2.5e-28 98.0 0.1 4.2e-28 97.3 0.1 1.3 1 0 0 1 1 1 1 E2 binding domain Shikimate_DH PF01488.20 KXS09596.1 - 0.004 17.2 0.0 0.0084 16.2 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 KXS09596.1 - 0.02 15.5 0.0 0.043 14.4 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase zf-C3HC4_3 PF13920.6 KXS09596.1 - 0.038 13.9 1.0 3.9 7.4 0.2 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Ecm33 PF12454.8 KXS09596.1 - 0.066 13.4 0.8 0.13 12.4 0.8 1.5 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein E1_UFD PF09358.10 KXS09596.1 - 0.068 13.9 0.0 0.13 13.0 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin fold domain FA_hydroxylase PF04116.13 KXS09598.1 - 1.9e-17 63.8 17.6 1.9e-17 63.8 17.6 1.7 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily LRR_4 PF12799.7 KXS09599.1 - 4.8e-38 128.5 16.7 4.1e-05 23.9 0.2 9.8 6 3 4 11 11 11 11 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXS09599.1 - 6.2e-35 118.8 15.6 3.5e-06 26.7 0.1 10.5 8 3 3 11 11 11 8 Leucine rich repeat LRR_9 PF14580.6 KXS09599.1 - 9.2e-13 48.1 7.6 8.5e-07 28.6 0.3 5.0 3 2 2 5 5 5 3 Leucine-rich repeat LRR_1 PF00560.33 KXS09599.1 - 9e-10 37.7 11.9 37 5.4 0.2 10.6 13 0 0 13 13 13 0 Leucine Rich Repeat LRR_6 PF13516.6 KXS09599.1 - 3.1e-07 29.9 31.1 1.2 9.4 0.3 11.5 12 0 0 12 12 12 3 Leucine Rich repeat Exo_endo_phos PF03372.23 KXS09600.1 - 1.2e-09 38.0 0.0 2.4e-09 37.0 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family PNP_UDP_1 PF01048.20 KXS09602.1 - 4.9e-36 124.1 0.0 6.5e-36 123.8 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily NUP PF06516.11 KXS09602.1 - 0.00015 21.1 0.1 0.00038 19.8 0.1 1.6 2 0 0 2 2 2 1 Purine nucleoside permease (NUP) DUF1968 PF09291.10 KXS09603.1 - 0.0023 18.0 0.2 0.0046 17.0 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1968) DDE_3 PF13358.6 KXS09604.1 - 1.5e-12 47.5 0.0 5.2e-06 26.3 0.0 3.1 3 0 0 3 3 3 2 DDE superfamily endonuclease EMC1_C PF07774.13 KXS09605.1 - 1.4e-62 211.1 0.0 2.2e-62 210.5 0.0 1.3 1 0 0 1 1 1 1 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 KXS09605.1 - 0.0004 20.0 0.7 0.031 13.9 0.1 1.9 1 1 1 2 2 2 2 PQQ-like domain PQQ PF01011.21 KXS09605.1 - 0.062 13.3 0.2 0.72 9.9 0.0 2.7 3 0 0 3 3 3 0 PQQ enzyme repeat ABC1 PF03109.16 KXS09606.1 - 2.9e-32 111.3 0.0 4.7e-32 110.6 0.0 1.4 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 KXS09606.1 - 0.027 14.4 0.3 0.64 9.9 0.1 2.6 1 1 2 3 3 3 0 Phosphotransferase enzyme family CRIM PF16978.5 KXS09607.1 - 9.9e-35 119.7 0.0 1.6e-34 119.0 0.0 1.3 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), middle CRIM domain SIN1_PH PF16979.5 KXS09607.1 - 4.9e-08 33.2 0.0 1e-07 32.2 0.0 1.4 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology TUG-UBL1 PF11470.8 KXS09607.1 - 0.0014 18.8 0.1 0.0027 17.9 0.1 1.4 1 0 0 1 1 1 1 TUG ubiquitin-like domain RBD PF02196.15 KXS09607.1 - 0.0075 16.3 0.1 0.019 15.0 0.1 1.6 1 0 0 1 1 1 1 Raf-like Ras-binding domain RA PF00788.23 KXS09607.1 - 0.18 12.4 0.1 0.41 11.3 0.1 1.6 1 0 0 1 1 1 0 Ras association (RalGDS/AF-6) domain DUF295 PF03478.18 KXS09608.1 - 0.018 14.6 0.1 0.046 13.3 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF295) DUF295 PF03478.18 KXS09610.1 - 0.049 13.2 0.2 0.1 12.2 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF295) Pkinase PF00069.25 KXS09612.1 - 1.2e-65 221.5 0.0 1.8e-65 221.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS09612.1 - 7e-36 123.8 0.0 1.1e-35 123.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KXS09612.1 - 0.0023 17.3 0.0 0.0043 16.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KXS09612.1 - 0.017 13.9 0.0 0.033 13.0 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 KXS09612.1 - 0.058 12.7 0.1 5.1 6.3 0.0 2.3 2 0 0 2 2 2 0 Kinase-like APH PF01636.23 KXS09612.1 - 0.082 12.8 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family PI-PLC-X PF00388.19 KXS09614.1 - 0.00079 19.0 0.0 0.0012 18.4 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-C1 PF16670.5 KXS09614.1 - 0.19 10.8 0.2 2 7.4 0.2 2.3 1 1 0 1 1 1 0 Phosphoinositide phospholipase C, Ca2+-dependent Peptidase_M2 PF01401.18 KXS09615.1 - 1.5e-177 591.7 0.0 1.8e-177 591.4 0.0 1.0 1 0 0 1 1 1 1 Angiotensin-converting enzyme PHD PF00628.29 KXS09616.1 - 0.0068 16.3 2.2 0.012 15.5 2.2 1.4 1 0 0 1 1 1 1 PHD-finger Peptidase_M76 PF09768.9 KXS09617.1 - 2e-64 216.5 1.5 2.4e-64 216.2 1.5 1.1 1 0 0 1 1 1 1 Peptidase M76 family SprT-like PF10263.9 KXS09617.1 - 0.0024 17.7 0.2 0.0046 16.8 0.2 1.4 1 0 0 1 1 1 1 SprT-like family Peptidase_M91 PF14891.6 KXS09617.1 - 0.21 11.9 0.0 0.32 11.3 0.0 1.3 1 0 0 1 1 1 0 Effector protein MR_MLE_C PF13378.6 KXS09618.1 - 0.075 12.6 0.3 0.15 11.6 0.3 1.4 1 0 0 1 1 1 0 Enolase C-terminal domain-like TAF4 PF05236.14 KXS09619.1 - 8.5 6.0 9.1 17 5.1 9.1 1.7 1 1 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family zf-H2C2_2 PF13465.6 KXS09620.1 - 1.4e-09 37.9 3.4 0.00088 19.6 0.6 2.1 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 KXS09620.1 - 4.6e-09 36.2 11.8 1.3e-05 25.4 0.9 3.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXS09620.1 - 7.3e-06 26.4 9.5 0.0025 18.5 0.4 3.1 3 0 0 3 3 3 1 C2H2-type zinc finger zinc_ribbon_4 PF13717.6 KXS09620.1 - 0.0024 17.8 0.6 0.54 10.2 0.0 2.2 2 0 0 2 2 2 1 zinc-ribbon domain zf-C2H2_11 PF16622.5 KXS09620.1 - 0.0029 17.3 4.6 0.11 12.3 0.3 2.5 3 0 0 3 3 3 2 zinc-finger C2H2-type zinc_ribbon_15 PF17032.5 KXS09620.1 - 0.0034 18.1 0.2 0.0035 18.1 0.2 1.1 1 0 0 1 1 1 1 zinc-ribbon family zinc_ribbon_9 PF14369.6 KXS09620.1 - 0.0055 16.9 0.7 0.97 9.8 0.0 2.1 2 0 0 2 2 2 1 zinc-ribbon zf-met PF12874.7 KXS09620.1 - 0.0056 17.0 5.3 0.71 10.3 0.1 3.1 3 0 0 3 3 3 1 Zinc-finger of C2H2 type Trm112p PF03966.16 KXS09620.1 - 0.0066 17.0 0.9 0.67 10.6 0.1 2.1 1 1 1 2 2 2 1 Trm112p-like protein IBR PF01485.21 KXS09620.1 - 0.0086 16.3 0.4 0.011 16.0 0.4 1.1 1 0 0 1 1 1 1 IBR domain, a half RING-finger domain A2L_zn_ribbon PF08792.10 KXS09620.1 - 0.018 14.8 0.8 2.3 8.1 0.1 2.2 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-ribbon_3 PF13248.6 KXS09620.1 - 0.018 14.5 2.9 0.48 9.9 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf-NADH-PPase PF09297.11 KXS09620.1 - 0.02 14.5 1.2 0.83 9.4 0.1 2.3 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Zn-ribbon_8 PF09723.10 KXS09620.1 - 0.022 14.9 3.6 1.5 9.0 0.3 2.1 1 1 0 2 2 2 0 Zinc ribbon domain zf-C2H2_jaz PF12171.8 KXS09620.1 - 0.028 14.7 4.3 0.77 10.1 0.1 3.0 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Prok-RING_1 PF14446.6 KXS09620.1 - 0.036 14.0 0.6 0.74 9.8 0.6 2.1 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 zf-CSL PF05207.13 KXS09620.1 - 0.037 13.8 0.1 1.3 8.8 0.0 2.1 2 0 0 2 2 2 0 CSL zinc finger DNA_RNApol_7kD PF03604.13 KXS09620.1 - 0.049 13.3 1.1 1.9 8.2 0.4 2.2 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit zf-H2C2_5 PF13909.6 KXS09620.1 - 0.052 13.3 2.1 7.8 6.4 1.2 2.4 2 1 0 2 2 2 0 C2H2-type zinc-finger domain PriA_CRR PF18319.1 KXS09620.1 - 0.055 13.5 3.4 6.4 6.9 0.1 2.7 2 1 0 2 2 2 0 PriA DNA helicase Cys-rich region (CRR) domain DUF2318 PF10080.9 KXS09620.1 - 0.069 13.3 0.8 1.6 8.9 0.1 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2318) Nudix_N_2 PF14803.6 KXS09620.1 - 0.2 11.6 3.5 2.9 7.9 0.1 2.3 2 1 0 2 2 2 0 Nudix N-terminal zf-LYAR PF08790.11 KXS09620.1 - 0.22 11.5 2.2 4.2 7.4 0.0 2.5 3 0 0 3 3 2 0 LYAR-type C2HC zinc finger zf-C2HE PF16278.5 KXS09620.1 - 0.3 11.5 8.8 10 6.6 0.5 3.1 1 1 2 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger zf-MYND PF01753.18 KXS09620.1 - 0.85 9.8 6.0 1.6 8.9 1.1 2.5 1 1 1 2 2 2 0 MYND finger DSPc PF00782.20 KXS09621.1 - 7.1e-11 42.1 0.0 8.2e-11 41.9 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KXS09621.1 - 2.1e-06 27.5 0.0 2.9e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 KXS09621.1 - 0.00046 19.9 0.0 0.00058 19.6 0.0 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) SH3_9 PF14604.6 KXS09622.1 - 2.3e-05 24.2 0.0 4.3e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Ank_2 PF12796.7 KXS09622.1 - 0.0013 19.3 0.0 0.014 16.0 0.0 2.5 2 1 1 3 3 3 1 Ankyrin repeats (3 copies) Spc29 PF17082.5 KXS09622.1 - 0.0015 18.4 0.0 0.0023 17.8 0.0 1.2 1 0 0 1 1 1 1 Spindle Pole Component 29 Ank_4 PF13637.6 KXS09622.1 - 0.0034 17.9 0.0 0.095 13.3 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 KXS09622.1 - 0.0061 16.9 0.0 8.3 7.0 0.0 3.3 3 0 0 3 3 3 0 Ankyrin repeat Ank_3 PF13606.6 KXS09622.1 - 0.0064 16.9 0.0 0.058 14.0 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat SH3_1 PF00018.28 KXS09622.1 - 0.0088 15.6 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 1 SH3 domain ATG16 PF08614.11 KXS09622.1 - 0.013 15.8 0.2 0.019 15.2 0.2 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) HOOK PF05622.12 KXS09622.1 - 0.014 13.6 1.1 0.019 13.1 1.1 1.1 1 0 0 1 1 1 0 HOOK protein Ank_5 PF13857.6 KXS09622.1 - 0.02 15.2 0.0 0.13 12.7 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeats (many copies) ERM PF00769.19 KXS09622.1 - 0.027 14.3 2.1 0.041 13.7 2.1 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family CAGE1 PF15066.6 KXS09622.1 - 0.034 12.8 0.3 0.048 12.3 0.3 1.1 1 0 0 1 1 1 0 Cancer-associated gene protein 1 family KASH_CCD PF14662.6 KXS09622.1 - 0.042 13.7 2.8 0.061 13.2 2.8 1.1 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Cytochrom_B562 PF07361.11 KXS09622.1 - 0.07 13.8 0.3 0.12 13.1 0.3 1.3 1 0 0 1 1 1 0 Cytochrome b562 SH3_2 PF07653.17 KXS09622.1 - 0.071 12.8 0.0 0.23 11.2 0.0 1.8 2 0 0 2 2 2 0 Variant SH3 domain PKcGMP_CC PF16808.5 KXS09622.1 - 0.11 12.4 1.6 1.2 9.0 1.1 2.4 1 1 2 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase AAA_13 PF13166.6 KXS09622.1 - 0.16 10.6 2.5 0.22 10.1 2.5 1.0 1 0 0 1 1 1 0 AAA domain HEAT_2 PF13646.6 KXS09622.1 - 0.17 12.3 2.8 13 6.3 0.0 3.7 3 0 0 3 3 3 0 HEAT repeats CEP209_CC5 PF16574.5 KXS09622.1 - 0.18 12.0 2.5 0.29 11.3 2.5 1.3 1 0 0 1 1 1 0 Coiled-coil region of centrosome protein CE290 FliJ PF02050.16 KXS09622.1 - 0.31 11.3 2.1 0.5 10.6 2.1 1.3 1 0 0 1 1 1 0 Flagellar FliJ protein Spc7 PF08317.11 KXS09622.1 - 0.73 8.7 3.6 1.1 8.1 3.6 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein SlyX PF04102.12 KXS09622.1 - 1.8 9.2 4.6 0.37 11.4 0.5 2.0 2 0 0 2 2 1 0 SlyX BTB_2 PF02214.22 KXS09623.1 - 2.1e-05 24.8 0.0 8.9e-05 22.8 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain adh_short_C2 PF13561.6 KXS09625.1 - 7.5e-54 182.8 6.7 9.2e-54 182.5 6.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXS09625.1 - 4.8e-50 169.7 3.6 6.6e-50 169.3 3.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXS09625.1 - 1.1e-16 61.3 2.3 1.1e-16 61.3 2.3 1.5 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KXS09625.1 - 0.00063 19.3 0.6 0.006 16.1 0.6 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family AdoHcyase_NAD PF00670.21 KXS09625.1 - 0.13 12.3 2.3 0.18 11.9 2.0 1.5 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Eno-Rase_NADH_b PF12242.8 KXS09625.1 - 0.23 11.2 4.9 0.24 11.2 0.9 2.5 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase TPP_enzyme_N PF02776.18 KXS09625.1 - 1.7 8.2 6.1 1.4 8.5 1.7 2.3 1 1 0 2 2 2 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain Erf4 PF10256.9 KXS09626.1 - 0.00024 21.2 0.4 0.0026 17.8 0.0 2.2 1 1 1 2 2 2 1 Golgin subfamily A member 7/ERF4 family AAA PF00004.29 KXS09627.1 - 3.5e-66 221.6 0.0 2.2e-33 115.5 0.0 3.3 3 0 0 3 3 3 3 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KXS09627.1 - 8.1e-15 55.6 2.5 2.1e-07 31.5 0.0 4.5 3 1 0 3 3 3 2 AAA ATPase domain AAA_lid_3 PF17862.1 KXS09627.1 - 9.2e-13 47.8 2.3 1.6e-07 31.0 0.3 2.6 2 0 0 2 2 2 2 AAA+ lid domain AAA_5 PF07728.14 KXS09627.1 - 2e-11 44.1 0.5 2.4e-05 24.3 0.2 4.4 3 2 0 3 3 3 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KXS09627.1 - 3.1e-10 40.0 0.0 0.0055 16.5 0.0 4.1 4 0 0 4 4 4 2 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 KXS09627.1 - 2.6e-08 34.1 0.1 0.0049 17.0 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.6 KXS09627.1 - 5.2e-07 30.0 0.3 0.031 14.6 0.1 5.0 4 2 0 5 5 5 1 AAA domain AAA_2 PF07724.14 KXS09627.1 - 1.1e-05 25.7 0.0 0.0023 18.0 0.0 2.6 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) NACHT PF05729.12 KXS09627.1 - 8.1e-05 22.6 0.1 0.076 12.9 0.0 3.5 4 0 0 4 4 4 1 NACHT domain AAA_3 PF07726.11 KXS09627.1 - 0.00014 21.7 0.0 0.027 14.3 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 KXS09627.1 - 0.00017 21.4 0.0 0.05 13.3 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_25 PF13481.6 KXS09627.1 - 0.00018 21.2 0.4 0.19 11.3 0.0 2.7 2 1 0 2 2 2 2 AAA domain AAA_28 PF13521.6 KXS09627.1 - 0.0002 21.6 0.1 0.045 14.0 0.0 2.8 3 0 0 3 3 2 1 AAA domain RNA_helicase PF00910.22 KXS09627.1 - 0.0003 21.1 0.0 0.53 10.7 0.0 3.3 4 0 0 4 4 3 1 RNA helicase TsaE PF02367.17 KXS09627.1 - 0.00039 20.4 0.0 0.1 12.6 0.0 2.3 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_11 PF13086.6 KXS09627.1 - 0.001 18.9 0.0 0.26 11.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KXS09627.1 - 0.0012 19.4 0.0 0.37 11.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 KXS09627.1 - 0.0044 17.0 0.0 0.56 10.1 0.0 2.2 2 0 0 2 2 2 1 Rad17 P-loop domain NTPase_1 PF03266.15 KXS09627.1 - 0.0045 16.9 0.0 1.5 8.7 0.0 2.3 2 0 0 2 2 2 1 NTPase Mg_chelatase PF01078.21 KXS09627.1 - 0.0059 16.0 0.8 3 7.2 0.0 2.8 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI ABC_tran PF00005.27 KXS09627.1 - 0.0066 17.0 0.0 13 6.3 0.0 3.2 3 0 0 3 3 3 0 ABC transporter AAA_19 PF13245.6 KXS09627.1 - 0.018 15.4 0.0 0.28 11.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 KXS09627.1 - 0.019 14.2 0.0 8.9 5.4 0.0 2.8 3 0 0 3 3 3 0 NB-ARC domain AAA_24 PF13479.6 KXS09627.1 - 0.026 14.2 0.0 0.84 9.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 KXS09627.1 - 0.031 14.0 0.0 1.9 8.2 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_7 PF12775.7 KXS09627.1 - 0.046 13.2 0.0 3.2 7.2 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region TIP49 PF06068.13 KXS09627.1 - 0.066 12.4 0.0 6.7 5.8 0.0 2.2 2 0 0 2 2 2 0 TIP49 P-loop domain AAA_30 PF13604.6 KXS09627.1 - 0.13 11.9 5.6 0.3 10.8 0.1 3.1 3 1 0 3 3 3 0 AAA domain cobW PF02492.19 KXS09627.1 - 0.23 11.0 0.1 1.1 8.8 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Bac_DnaA PF00308.18 KXS09627.1 - 0.3 10.9 0.0 0.99 9.2 0.0 1.8 2 0 0 2 2 2 0 Bacterial dnaA protein Ank_2 PF12796.7 KXS09628.1 - 6.5e-43 145.2 8.2 3.9e-08 33.8 0.2 7.0 3 1 5 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXS09628.1 - 2.3e-33 114.1 17.4 0.0014 19.2 0.1 9.2 8 2 2 10 10 10 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXS09628.1 - 2.2e-24 82.9 10.9 0.86 10.4 0.0 14.0 14 1 1 15 15 15 6 Ankyrin repeat Ank PF00023.30 KXS09628.1 - 3.8e-20 71.4 30.9 0.16 12.5 0.1 13.8 13 2 2 15 15 15 8 Ankyrin repeat Ank_5 PF13857.6 KXS09628.1 - 6.7e-11 42.2 15.0 0.19 12.1 0.0 9.4 5 5 7 12 12 12 4 Ankyrin repeats (many copies) AMP-binding PF00501.28 KXS09629.1 - 1.8e-81 273.9 0.0 2.4e-81 273.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXS09629.1 - 5.6e-18 65.7 0.3 1.3e-17 64.5 0.3 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PfkB PF00294.24 KXS09630.1 - 3.9e-30 105.2 0.1 8.3e-30 104.1 0.1 1.6 1 1 0 1 1 1 1 pfkB family carbohydrate kinase KH_1 PF00013.29 KXS09630.1 - 0.014 15.2 0.0 0.027 14.3 0.0 1.4 1 0 0 1 1 1 0 KH domain TatD_DNase PF01026.21 KXS09631.1 - 2.7e-36 125.3 0.0 3.5e-36 124.9 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase BAR PF03114.18 KXS09633.1 - 9.1e-34 117.1 1.1 1.2e-33 116.8 1.1 1.1 1 0 0 1 1 1 1 BAR domain GlcNAc PF11397.8 KXS09634.1 - 3.9e-50 171.3 0.0 5.7e-39 134.6 0.0 2.6 1 1 1 2 2 2 2 Glycosyltransferase (GlcNAc) 2OG-FeII_Oxy_3 PF13640.6 KXS09634.1 - 3.1e-17 63.2 0.0 7.6e-17 62.0 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 KXS09634.1 - 1.7e-07 31.8 0.0 3.2e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF676 PF05057.14 KXS09635.1 - 6.7e-39 133.6 0.0 1.2e-38 132.8 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 KXS09635.1 - 0.016 15.1 0.0 0.025 14.4 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Hemerythrin PF01814.23 KXS09636.1 - 7.7e-14 52.4 2.7 1.3e-13 51.7 2.7 1.3 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Mac PF12464.8 KXS09636.1 - 0.041 14.1 0.2 0.11 12.7 0.2 1.7 1 0 0 1 1 1 0 Maltose acetyltransferase Mito_carr PF00153.27 KXS09639.1 - 7.7e-24 83.4 4.5 1.4e-10 41.0 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KXS09639.1 - 0.00034 19.8 1.0 0.0055 15.9 0.4 2.5 1 1 1 2 2 2 2 Gammaproteobacterial serine protease Erv26 PF04148.13 KXS09640.1 - 4.1e-58 196.6 14.5 1.6e-57 194.6 14.5 1.8 1 1 0 1 1 1 1 Transmembrane adaptor Erv26 KH_1 PF00013.29 KXS09641.1 - 1.4e-23 82.5 0.2 1.8e-13 50.1 0.1 2.2 2 0 0 2 2 2 2 KH domain KH_2 PF07650.17 KXS09641.1 - 3.4e-07 30.0 1.7 0.0046 16.8 0.4 2.3 2 0 0 2 2 2 2 KH domain KH_4 PF13083.6 KXS09641.1 - 0.0021 17.9 0.5 1.3 9.0 0.1 2.3 2 0 0 2 2 2 2 KH domain KH_5 PF13184.6 KXS09641.1 - 0.024 14.7 1.1 4.4 7.5 0.2 2.4 2 0 0 2 2 2 0 NusA-like KH domain zf-CCHC_4 PF14392.6 KXS09642.1 - 0.072 12.8 0.7 0.14 11.9 0.7 1.4 1 0 0 1 1 1 0 Zinc knuckle DUF3237 PF11578.8 KXS09644.1 - 6.6e-31 107.2 0.0 7.6e-31 107.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) SGL PF08450.12 KXS09644.1 - 0.069 12.7 0.0 0.074 12.6 0.0 1.2 1 0 0 1 1 1 0 SMP-30/Gluconolactonase/LRE-like region bZIP_1 PF00170.21 KXS09645.1 - 1.6e-09 37.8 5.2 3.2e-09 36.8 5.2 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KXS09645.1 - 2e-09 37.4 6.1 3.8e-09 36.5 6.1 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KXS09645.1 - 0.00076 19.9 4.2 0.00076 19.9 4.2 1.8 2 0 0 2 2 2 1 bZIP Maf transcription factor Shugoshin_N PF07558.11 KXS09645.1 - 0.0067 16.3 1.1 0.012 15.4 1.1 1.3 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region TSC22 PF01166.18 KXS09645.1 - 0.098 13.0 0.2 0.25 11.7 0.2 1.6 1 0 0 1 1 1 0 TSC-22/dip/bun family SOG2 PF10428.9 KXS09645.1 - 8 5.5 15.1 11 5.0 15.1 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein Pyridoxal_deC PF00282.19 KXS09646.1 - 1.2e-15 57.1 0.0 1.2e-14 53.9 0.0 2.0 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 KXS09646.1 - 1.3e-09 37.6 0.0 9.1e-09 34.7 0.0 2.2 2 1 0 2 2 2 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 KXS09646.1 - 1.2e-05 24.7 0.0 0.00016 21.0 0.0 2.1 1 1 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 KXS09646.1 - 0.00022 20.7 0.0 0.00036 20.0 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family FAM176 PF14851.6 KXS09647.1 - 7.3 6.2 9.8 1 9.0 1.3 2.2 1 1 1 2 2 2 0 FAM176 family ASH PF15780.5 KXS09648.1 - 2.1e-05 24.6 0.2 0.45 10.8 0.0 3.7 4 0 0 4 4 4 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin UPA PF17217.3 KXS09648.1 - 0.016 15.1 0.7 0.091 12.6 0.7 2.1 1 1 0 1 1 1 0 UPA domain TMEM131_like PF12371.8 KXS09648.1 - 0.19 12.0 1.6 56 4.1 0.0 3.7 3 1 0 3 3 3 0 Transmembrane protein 131-like Motile_Sperm PF00635.26 KXS09648.1 - 0.28 11.0 1.7 4.2 7.3 0.0 3.0 4 0 0 4 4 4 0 MSP (Major sperm protein) domain ASH PF15780.5 KXS09649.1 - 2.6e-07 30.7 0.7 0.059 13.6 0.1 7.1 8 0 0 8 8 8 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 KXS09649.1 - 0.00028 20.7 0.1 1.4 8.8 0.0 3.9 4 0 0 4 4 4 2 MSP (Major sperm protein) domain Ank PF00023.30 KXS09650.1 - 3.5e-12 46.2 0.4 0.59 10.7 0.2 6.5 6 1 0 6 6 6 3 Ankyrin repeat Ank_2 PF12796.7 KXS09650.1 - 3.2e-11 43.6 0.8 0.21 12.2 0.0 5.4 4 1 1 5 5 5 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXS09650.1 - 4.5e-10 38.9 2.9 0.21 12.3 0.1 5.9 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 KXS09650.1 - 1.6e-05 25.1 0.1 6 7.3 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXS09650.1 - 4.7e-05 23.9 0.4 5 7.8 0.1 5.4 4 1 1 5 5 5 1 Ankyrin repeats (many copies) Pkinase PF00069.25 KXS09651.1 - 7e-24 84.6 0.0 9.2e-24 84.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS09651.1 - 5.2e-19 68.5 0.0 6.2e-19 68.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXS09651.1 - 0.0031 17.5 0.0 0.0052 16.7 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KXS09651.1 - 0.012 14.9 0.0 0.017 14.4 0.0 1.3 1 0 0 1 1 1 0 Kinase-like FAD_binding_4 PF01565.23 KXS09652.1 - 9.6e-25 86.9 0.6 1.9e-24 86.0 0.6 1.5 1 0 0 1 1 1 1 FAD binding domain Sec1 PF00995.23 KXS09653.1 - 3.3e-86 290.8 0.0 5.6e-86 290.0 0.0 1.4 1 1 0 1 1 1 1 Sec1 family bZIP_2 PF07716.15 KXS09654.1 - 6.6e-05 22.9 6.3 0.00012 22.1 6.3 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 KXS09654.1 - 0.004 17.2 7.1 0.0072 16.4 7.1 1.3 1 0 0 1 1 1 1 bZIP transcription factor Sec1 PF00995.23 KXS09655.1 - 9e-113 378.5 0.0 1.1e-112 378.2 0.0 1.1 1 0 0 1 1 1 1 Sec1 family PDZ_1 PF12812.7 KXS09655.1 - 0.11 12.5 0.0 0.47 10.5 0.0 2.1 1 0 0 1 1 1 0 PDZ-like domain Ank_2 PF12796.7 KXS09657.1 - 1.3e-08 35.3 0.6 0.0023 18.5 0.1 2.3 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXS09657.1 - 1.6e-07 31.7 2.2 4.3e-05 24.0 0.4 3.3 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXS09657.1 - 1.9e-06 28.0 2.2 1.9 8.9 0.0 4.4 3 2 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXS09657.1 - 1.2e-05 25.3 1.1 0.66 10.7 0.1 4.7 5 0 0 5 5 5 2 Ankyrin repeat Ank PF00023.30 KXS09657.1 - 0.018 15.5 2.4 2.6 8.7 0.3 3.8 3 1 0 3 3 3 0 Ankyrin repeat LRR_4 PF12799.7 KXS09659.1 - 3.2e-09 36.9 2.2 0.0009 19.6 0.3 2.4 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXS09659.1 - 0.00014 21.5 4.9 0.00056 19.6 4.4 2.1 1 1 0 1 1 1 1 Leucine rich repeat LRR_6 PF13516.6 KXS09659.1 - 0.045 13.8 1.4 1.6 9.0 0.2 3.3 3 0 0 3 3 3 0 Leucine Rich repeat LRR_1 PF00560.33 KXS09659.1 - 0.094 13.3 0.5 14 6.7 0.0 3.4 3 0 0 3 3 3 0 Leucine Rich Repeat zf-C2H2 PF00096.26 KXS09660.1 - 2.7e-06 27.5 3.5 0.16 12.5 0.3 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXS09660.1 - 0.00025 21.6 5.8 0.47 11.4 0.2 3.8 3 1 0 3 3 3 2 C2H2-type zinc finger zf-C2HC_2 PF13913.6 KXS09660.1 - 1.8 8.5 7.8 11 6.0 3.3 3.2 2 1 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2 PF00096.26 KXS09661.1 - 2.1e-06 27.9 2.2 0.29 11.7 0.2 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXS09661.1 - 0.0011 19.7 4.2 2.6 9.1 0.1 3.9 3 1 0 3 3 3 2 C2H2-type zinc finger PX PF00787.24 KXS09663.1 - 0.0017 18.3 0.0 0.005 16.8 0.0 1.7 1 0 0 1 1 1 1 PX domain Ank_3 PF13606.6 KXS09664.1 - 0.0072 16.7 0.0 3.8 8.4 0.0 3.6 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.7 KXS09664.1 - 0.012 16.1 0.0 3.2 8.4 0.0 3.1 3 0 0 3 3 3 0 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXS09664.1 - 0.19 12.3 0.0 23 5.7 0.0 3.0 4 0 0 4 4 4 0 Ankyrin repeats (many copies) p450 PF00067.22 KXS09665.1 - 9.7e-73 245.5 0.0 1.4e-72 245.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 His_Phos_2 PF00328.22 KXS09667.1 - 1.4e-07 31.2 0.0 0.00062 19.2 0.0 2.4 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) zf-RING_2 PF13639.6 KXS09668.1 - 5e-11 42.8 3.7 8.3e-11 42.0 3.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KXS09668.1 - 8.9e-08 31.9 3.1 1.6e-07 31.1 3.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KXS09668.1 - 1.5e-07 31.0 1.6 2.7e-07 30.2 1.6 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 KXS09668.1 - 2.9e-06 27.0 0.8 5.7e-06 26.1 0.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KXS09668.1 - 3.3e-06 27.3 4.4 7.3e-06 26.2 4.4 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KXS09668.1 - 6.5e-06 26.1 2.4 6.3e-05 22.9 3.4 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 KXS09668.1 - 0.00013 22.0 1.2 0.00023 21.2 1.2 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 KXS09668.1 - 0.00053 19.9 0.4 0.00098 19.0 0.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KXS09668.1 - 0.00064 19.5 0.8 0.0011 18.8 0.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KXS09668.1 - 0.0069 16.0 2.2 0.013 15.1 2.2 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 KXS09668.1 - 0.024 14.8 3.0 0.17 12.1 3.0 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain Prok-RING_4 PF14447.6 KXS09668.1 - 0.068 13.0 2.6 0.17 11.8 2.6 1.7 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 KXS09668.1 - 0.081 12.7 1.3 0.13 12.0 1.3 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3H2C3 PF17122.5 KXS09668.1 - 0.11 12.6 2.0 0.22 11.6 2.0 1.6 1 1 0 1 1 1 0 Zinc-finger zf-C3HC4_4 PF15227.6 KXS09668.1 - 0.47 10.7 3.6 1.1 9.5 3.6 1.6 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING LMBR1 PF04791.16 KXS09670.1 - 5.7 5.7 7.3 6.2 5.6 7.3 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein AAA_11 PF13086.6 KXS09670.1 - 8.2 6.1 12.1 9.2 6.0 12.1 1.0 1 0 0 1 1 1 0 AAA domain MFS_1 PF07690.16 KXS09672.1 - 2.1e-33 115.7 28.7 2.1e-33 115.7 28.7 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily BLM10_mid PF16507.5 KXS09674.1 - 9.6e-129 430.4 0.0 2.2e-128 429.2 0.0 1.6 2 0 0 2 2 2 1 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 KXS09674.1 - 3.5e-36 123.0 0.0 7.3e-30 102.7 0.0 3.6 3 0 0 3 3 3 2 Domain of unknown function (DUF3437) HEAT_EZ PF13513.6 KXS09674.1 - 1.3e-05 25.6 0.7 1.2 9.7 0.0 5.1 4 1 0 4 4 4 2 HEAT-like repeat HEAT_2 PF13646.6 KXS09674.1 - 0.0063 16.9 2.1 7.2 7.1 0.1 4.0 3 0 0 3 3 3 2 HEAT repeats Ribonuc_2-5A PF06479.12 KXS09675.1 - 1.5e-24 86.6 0.0 2.8e-24 85.7 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase PF00069.25 KXS09675.1 - 0.00024 20.5 0.0 0.00036 20.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Cyclin_N PF00134.23 KXS09676.1 - 1.3e-25 89.6 0.0 2.2e-25 88.9 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Glyco_hyd_101C PF17451.2 KXS09677.1 - 0.0034 17.7 0.0 0.62 10.4 0.0 2.3 2 0 0 2 2 2 2 Glycosyl hydrolase 101 beta sandwich domain Palm_thioest PF02089.15 KXS09678.1 - 1.7e-75 254.0 0.0 2e-75 253.8 0.0 1.1 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF1262 PF06880.11 KXS09678.1 - 0.17 12.4 0.1 0.53 10.7 0.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1262) DUF2183 PF09949.9 KXS09680.1 - 1.4e-09 38.1 0.0 2.1e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) Pyr_redox_3 PF13738.6 KXS09681.1 - 1.4e-15 57.3 0.0 1e-07 31.5 0.0 3.4 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KXS09681.1 - 1.7e-13 49.9 0.1 1.8e-11 43.2 0.0 3.4 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KXS09681.1 - 1.5e-10 40.8 0.0 1.1e-08 34.7 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXS09681.1 - 8.3e-09 35.6 0.0 1.1e-07 32.0 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KXS09681.1 - 2.1e-07 30.4 0.2 2.8e-05 23.4 0.0 3.3 3 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KXS09681.1 - 2.3e-05 24.1 0.0 0.00044 19.9 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KXS09681.1 - 0.0018 17.7 0.1 0.003 17.0 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KXS09681.1 - 0.002 17.4 0.0 0.64 9.2 0.0 2.2 2 0 0 2 2 2 2 Thi4 family FAD_binding_2 PF00890.24 KXS09681.1 - 0.0049 16.0 0.1 0.0083 15.2 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 KXS09681.1 - 0.007 16.4 0.0 0.74 9.8 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 KXS09681.1 - 0.0095 16.5 0.0 2.6 8.7 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 KXS09681.1 - 0.04 14.0 0.0 0.55 10.3 0.0 2.3 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Staph_opine_DH PF10100.9 KXS09681.1 - 0.084 11.5 0.1 0.83 8.2 0.0 2.0 2 0 0 2 2 2 0 Staphylopine dehydrogenase NAD_binding_7 PF13241.6 KXS09681.1 - 0.17 12.3 0.1 1.7 9.2 0.0 2.2 2 0 0 2 2 2 0 Putative NAD(P)-binding HI0933_like PF03486.14 KXS09681.1 - 0.18 10.5 0.3 0.43 9.2 0.4 1.6 2 0 0 2 2 2 0 HI0933-like protein CBP_BcsG PF11658.8 KXS09683.1 - 0.0099 14.3 0.0 0.016 13.7 0.0 1.2 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsG Per1 PF04080.13 KXS09684.1 - 5.2e-74 249.2 3.5 1.6e-54 185.3 0.6 2.1 2 0 0 2 2 2 2 Per1-like family Acetyltransf_1 PF00583.25 KXS09687.1 - 8.9e-11 42.1 0.0 1.2e-10 41.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXS09687.1 - 1.3e-06 28.7 0.0 2.7e-06 27.7 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KXS09687.1 - 0.00011 22.9 0.0 0.00013 22.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXS09687.1 - 0.00014 21.7 0.0 0.00025 21.0 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 KXS09687.1 - 0.00066 19.6 0.0 0.00095 19.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KXS09687.1 - 0.0024 18.0 0.0 0.003 17.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Zn_clus PF00172.18 KXS09688.1 - 2.2e-08 34.1 9.7 2.2e-08 34.1 9.7 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2659 PF10858.8 KXS09689.1 - 0.0071 16.0 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2659) Peptidase_S58 PF03576.14 KXS09690.1 - 6.1e-98 328.0 0.1 7e-98 327.8 0.1 1.0 1 0 0 1 1 1 1 Peptidase family S58 BKACE PF05853.12 KXS09691.1 - 1.3e-54 185.4 0.0 1.5e-54 185.2 0.0 1.0 1 0 0 1 1 1 1 beta-keto acid cleavage enzyme LRR_6 PF13516.6 KXS09693.1 - 0.082 13.0 1.3 7.6 6.9 0.2 3.1 3 0 0 3 3 3 0 Leucine Rich repeat adh_short_C2 PF13561.6 KXS09695.1 - 1.6e-28 99.8 0.1 2.1e-28 99.5 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXS09695.1 - 7e-17 61.5 0.2 1.8e-16 60.2 0.2 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXS09695.1 - 0.15 12.0 1.0 1.2 9.1 0.4 2.1 1 1 1 2 2 2 0 KR domain MBOAT PF03062.19 KXS09696.1 - 1.2e-37 130.1 4.5 1.2e-37 130.1 4.5 2.0 2 1 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family zf-C2H2 PF00096.26 KXS09697.1 - 0.00036 20.8 0.8 0.00085 19.7 0.8 1.7 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXS09697.1 - 0.0069 17.1 1.1 0.016 16.0 0.4 2.0 2 0 0 2 2 2 1 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KXS09697.1 - 0.24 11.9 0.4 0.24 11.9 0.4 1.8 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2HC_2 PF13913.6 KXS09697.1 - 0.54 10.2 4.1 1.3 9.0 3.2 2.2 1 1 1 2 2 2 0 zinc-finger of a C2HC-type Ank PF00023.30 KXS09700.1 - 1.9e-05 24.9 0.3 0.022 15.2 0.3 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 KXS09700.1 - 0.00062 20.0 0.0 0.018 15.5 0.1 2.7 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.7 KXS09700.1 - 0.00092 19.8 0.0 0.037 14.6 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Exonuc_VII_S PF02609.16 KXS09700.1 - 0.029 14.4 0.0 0.068 13.2 0.0 1.6 1 0 0 1 1 1 0 Exonuclease VII small subunit Metal_resist PF13801.6 KXS09700.1 - 0.033 14.4 3.6 0.097 12.9 3.6 1.8 1 0 0 1 1 1 0 Heavy-metal resistance ATG16 PF08614.11 KXS09700.1 - 0.04 14.2 0.5 0.054 13.7 0.5 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Sigma70_ner PF04546.13 KXS09700.1 - 0.054 13.4 0.0 0.076 12.9 0.0 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region ABC_tran_CTD PF16326.5 KXS09700.1 - 0.091 13.0 0.2 0.2 11.9 0.1 1.6 1 1 0 1 1 1 0 ABC transporter C-terminal domain FAD_binding_2 PF00890.24 KXS09701.1 - 1.7e-77 261.2 2.0 2.1e-77 260.9 2.0 1.1 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.28 KXS09701.1 - 5.6e-21 74.5 0.1 2.3e-20 72.5 0.1 2.1 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.24 KXS09701.1 - 5.1e-13 49.3 1.6 1.4e-12 47.9 1.6 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXS09701.1 - 4e-08 33.4 0.4 2.6e-07 30.8 0.2 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KXS09701.1 - 7.5e-08 32.1 2.7 1.2e-07 31.4 2.7 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXS09701.1 - 2.1e-07 30.5 1.3 1.7e-06 27.5 1.4 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXS09701.1 - 1.2e-05 24.7 0.5 0.00073 18.8 0.3 2.3 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 KXS09701.1 - 0.00021 20.6 0.5 0.00038 19.8 0.2 1.5 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 KXS09701.1 - 0.00039 19.2 0.5 0.00039 19.2 0.5 2.8 3 0 0 3 3 3 1 HI0933-like protein GIDA PF01134.22 KXS09701.1 - 0.0011 18.2 2.5 0.016 14.3 1.2 2.3 2 0 0 2 2 2 1 Glucose inhibited division protein A Amino_oxidase PF01593.24 KXS09701.1 - 0.0014 18.1 0.7 0.053 12.8 0.1 2.4 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 KXS09701.1 - 0.0041 17.6 0.9 0.0083 16.7 0.1 2.0 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXS09701.1 - 0.0064 15.8 0.4 0.087 12.1 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXS09701.1 - 0.0069 16.4 1.4 0.1 12.6 1.4 2.3 1 1 0 1 1 1 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 KXS09701.1 - 0.025 13.7 0.3 1.2 8.2 0.0 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.21 KXS09701.1 - 0.03 13.6 0.8 0.052 12.8 0.8 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 KXS09701.1 - 0.079 13.2 2.1 0.32 11.2 0.4 2.6 3 0 0 3 3 3 0 TrkA-N domain NAD_binding_7 PF13241.6 KXS09701.1 - 0.16 12.5 0.0 0.38 11.2 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding Ribosomal_60s PF00428.19 KXS09701.1 - 5.5 7.6 9.4 20 5.9 9.4 2.0 1 0 0 1 1 1 0 60s Acidic ribosomal protein Synaptobrevin PF00957.21 KXS09702.1 - 2.2e-33 113.9 0.4 3.5e-33 113.3 0.4 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 KXS09702.1 - 8.6e-26 89.8 0.0 1.5e-25 89.1 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Brix PF04427.18 KXS09703.1 - 1.6e-28 100.1 0.3 3e-28 99.3 0.3 1.4 1 0 0 1 1 1 1 Brix domain Rad51 PF08423.11 KXS09704.1 - 1.4e-126 421.0 0.0 1.7e-126 420.7 0.0 1.1 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 KXS09704.1 - 3.8e-12 46.3 0.0 5.1e-12 45.8 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.6 KXS09704.1 - 8.3e-11 41.8 0.1 1.2e-10 41.3 0.1 1.2 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.6 KXS09704.1 - 1.5e-08 35.1 0.1 3.3e-08 34.0 0.1 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain ATPase PF06745.13 KXS09704.1 - 9.8e-06 25.1 0.0 1.7e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 KaiC HhH-GPD PF00730.25 KXS09704.1 - 0.00085 19.7 0.0 0.027 14.9 0.0 2.2 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein DnaB_C PF03796.15 KXS09704.1 - 0.005 16.2 0.2 0.063 12.6 0.0 2.2 1 1 0 2 2 2 1 DnaB-like helicase C terminal domain AAA_24 PF13479.6 KXS09704.1 - 0.0078 16.0 0.0 0.014 15.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain HHH PF00633.23 KXS09704.1 - 0.01 15.6 0.0 0.021 14.7 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif AAA_22 PF13401.6 KXS09704.1 - 0.017 15.4 0.0 0.035 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain PAXNEB PF05625.11 KXS09704.1 - 0.2 10.8 0.9 1.2 8.2 0.5 2.0 1 1 1 2 2 2 0 PAXNEB protein PHF12_MRG_bd PF16737.5 KXS09704.1 - 0.21 11.3 0.5 0.38 10.5 0.1 1.6 2 0 0 2 2 2 0 PHD finger protein 12 MRG binding domain UNC-50 PF05216.13 KXS09705.1 - 3e-87 291.8 20.7 3.4e-87 291.6 20.7 1.0 1 0 0 1 1 1 1 UNC-50 family MRP-L20 PF12824.7 KXS09706.1 - 2.1e-16 60.6 0.3 2.4e-16 60.3 0.3 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Adhes-Ig_like PF09085.10 KXS09707.1 - 0.031 14.4 0.1 0.87 9.7 0.0 2.0 1 1 1 2 2 2 0 Adhesion molecule, immunoglobulin-like TauD PF02668.16 KXS09709.1 - 3.4e-51 174.6 1.3 4.6e-51 174.2 1.3 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family FAD_binding_2 PF00890.24 KXS09710.1 - 2.3e-76 257.6 13.8 1.3e-69 235.3 8.2 2.0 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 KXS09710.1 - 1.1e-16 61.3 6.7 1.1e-06 28.5 1.0 3.4 3 0 0 3 3 3 3 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXS09710.1 - 8.6e-11 41.9 5.2 0.00012 22.2 0.4 3.5 3 0 0 3 3 3 2 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KXS09710.1 - 1.1e-09 38.2 6.0 0.00026 20.5 1.8 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXS09710.1 - 5.7e-07 29.1 8.1 0.0031 16.8 1.7 3.8 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXS09710.1 - 1.4e-06 27.7 3.9 0.017 14.4 0.2 3.7 3 0 0 3 3 3 2 Thi4 family Lycopene_cycl PF05834.12 KXS09710.1 - 2.8e-05 23.3 0.4 0.082 11.9 0.0 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein HI0933_like PF03486.14 KXS09710.1 - 0.00022 20.1 5.4 0.16 10.6 0.2 3.4 4 0 0 4 4 4 2 HI0933-like protein GIDA PF01134.22 KXS09710.1 - 0.00072 18.7 8.3 0.31 10.1 0.2 3.9 4 0 0 4 4 4 2 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 KXS09710.1 - 0.00093 18.5 2.0 0.63 9.3 0.1 2.3 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.6 KXS09710.1 - 0.0017 18.3 0.6 0.33 10.9 0.1 3.0 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 KXS09710.1 - 0.0075 16.8 2.6 24 5.6 0.1 3.5 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KXS09710.1 - 0.0096 15.2 8.6 0.66 9.2 2.0 3.1 2 1 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.6 KXS09710.1 - 0.16 11.2 0.7 23 4.1 0.1 3.0 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Hydantoinase_B PF02538.14 KXS09711.1 - 3.6e-132 441.4 0.0 1.8e-131 439.1 0.0 1.9 2 0 0 2 2 2 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 KXS09711.1 - 8e-94 314.2 0.5 8e-94 314.2 0.5 2.4 3 0 0 3 3 3 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 KXS09711.1 - 3.1e-43 147.5 0.0 8e-41 139.7 0.0 2.5 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region MutL PF13941.6 KXS09711.1 - 0.00013 20.7 2.5 0.076 11.6 0.3 2.3 2 0 0 2 2 2 2 MutL protein Amidase PF01425.21 KXS09712.1 - 1.6e-50 172.4 0.4 7.9e-50 170.1 0.4 1.8 1 1 0 1 1 1 1 Amidase Amidase PF01425.21 KXS09713.1 - 7.8e-119 397.6 0.0 1.2e-118 396.9 0.0 1.3 1 1 0 1 1 1 1 Amidase F-box PF00646.33 KXS09714.1 - 1.2e-05 25.0 0.0 2.5e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KXS09714.1 - 0.05 13.5 0.0 0.13 12.2 0.0 1.8 1 0 0 1 1 1 0 F-box-like Polysacc_deac_1 PF01522.21 KXS09715.1 - 8.5e-16 58.0 0.0 1.2e-15 57.4 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 KXS09715.1 - 0.00015 21.5 0.7 0.0004 20.1 0.4 1.8 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2334) DUF2194 PF09960.9 KXS09715.1 - 0.088 11.1 0.0 0.11 10.8 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2194) Glyco_hydro_18 PF00704.28 KXS09716.1 - 5.4e-46 157.7 0.0 6.4e-46 157.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 CorC_HlyC PF03471.17 KXS09716.1 - 0.21 11.6 0.0 0.39 10.8 0.0 1.4 1 0 0 1 1 1 0 Transporter associated domain TLD PF07534.16 KXS09717.1 - 2.7e-19 69.8 0.0 8.5e-12 45.5 0.0 2.4 2 0 0 2 2 2 2 TLD Homeodomain PF00046.29 KXS09718.1 - 5.1e-18 64.7 0.6 5.4e-18 64.6 0.6 1.0 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KXS09718.1 - 0.00013 21.8 0.3 0.0002 21.2 0.3 1.3 1 0 0 1 1 1 1 Homeobox KN domain HTH_48 PF17906.1 KXS09718.1 - 0.044 13.9 0.1 0.24 11.5 0.1 1.9 1 1 1 2 2 2 0 HTH domain in Mos1 transposase Homez PF11569.8 KXS09718.1 - 0.046 13.2 0.0 0.067 12.7 0.0 1.2 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Pkinase_Tyr PF07714.17 KXS09719.1 - 7.7e-49 166.3 0.0 1.2e-48 165.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXS09719.1 - 6.3e-44 150.3 0.0 8.8e-44 149.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 KXS09719.1 - 6.8e-07 28.9 0.0 9e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KXS09719.1 - 0.00095 18.8 0.0 0.0019 17.8 0.0 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 KXS09719.1 - 0.0013 18.7 0.0 0.0026 17.7 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KXS09719.1 - 0.0019 17.6 0.0 0.0035 16.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family SH3_2 PF07653.17 KXS09719.1 - 0.14 11.8 0.1 0.44 10.3 0.0 1.8 2 0 0 2 2 2 0 Variant SH3 domain AAA_2 PF07724.14 KXS09721.1 - 1.7e-55 187.7 0.0 3.6e-52 176.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 KXS09721.1 - 1.2e-36 124.8 2.7 1.2e-36 124.8 2.7 3.5 4 1 1 5 5 4 1 AAA lid domain AAA PF00004.29 KXS09721.1 - 3.8e-24 85.6 0.1 5.3e-12 46.3 0.0 3.1 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 KXS09721.1 - 8.6e-22 77.0 3.6 1.3e-21 76.4 0.0 3.2 3 0 0 3 3 2 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 KXS09721.1 - 1.4e-15 57.5 4.8 1.1e-10 41.6 0.0 4.2 5 2 0 5 5 2 2 AAA domain (dynein-related subfamily) Clp_N PF02861.20 KXS09721.1 - 1.3e-14 54.0 5.8 6.7e-08 32.5 0.4 3.0 2 0 0 2 2 2 2 Clp amino terminal domain, pathogenicity island component AAA_16 PF13191.6 KXS09721.1 - 7.7e-11 42.7 16.8 3.7e-06 27.4 0.1 5.8 5 3 0 5 5 4 2 AAA ATPase domain AAA_22 PF13401.6 KXS09721.1 - 1.1e-09 38.7 1.9 0.006 16.9 0.0 4.9 2 2 1 3 3 3 2 AAA domain IstB_IS21 PF01695.17 KXS09721.1 - 6.9e-09 35.7 0.0 0.0019 17.9 0.0 2.8 2 0 0 2 2 2 2 IstB-like ATP binding protein Sigma54_activat PF00158.26 KXS09721.1 - 8.4e-09 35.3 0.1 6.6e-06 25.9 0.0 2.9 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_14 PF13173.6 KXS09721.1 - 2e-07 31.1 0.0 0.0086 16.1 0.0 3.8 4 0 0 4 4 4 2 AAA domain TniB PF05621.11 KXS09721.1 - 1.2e-06 28.0 0.0 0.0033 16.9 0.0 3.6 2 1 0 2 2 2 1 Bacterial TniB protein AAA_18 PF13238.6 KXS09721.1 - 1.9e-06 28.5 0.0 0.018 15.6 0.0 3.5 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 KXS09721.1 - 2.9e-06 26.9 0.0 0.018 14.5 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region Zeta_toxin PF06414.12 KXS09721.1 - 9.4e-06 25.0 2.9 0.0025 17.1 0.0 4.1 4 1 1 5 5 4 1 Zeta toxin Roc PF08477.13 KXS09721.1 - 1.5e-05 25.2 0.0 0.089 13.0 0.0 2.9 3 0 0 3 3 2 2 Ras of Complex, Roc, domain of DAPkinase ATPase_2 PF01637.18 KXS09721.1 - 1.7e-05 24.9 2.2 0.74 9.7 0.1 4.8 5 1 0 6 6 5 2 ATPase domain predominantly from Archaea NACHT PF05729.12 KXS09721.1 - 3.4e-05 23.8 0.0 0.085 12.8 0.0 2.7 2 0 0 2 2 2 2 NACHT domain RNA_helicase PF00910.22 KXS09721.1 - 5.1e-05 23.6 0.0 0.23 11.9 0.0 2.9 3 0 0 3 3 2 2 RNA helicase TsaE PF02367.17 KXS09721.1 - 6.2e-05 23.0 0.1 0.59 10.1 0.0 3.0 3 0 0 3 3 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 KXS09721.1 - 0.00012 21.6 0.8 0.68 9.3 0.0 3.7 3 1 0 4 4 4 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 KXS09721.1 - 0.00012 22.3 0.2 0.18 12.0 0.0 3.4 3 0 0 3 3 2 1 AAA domain AAA_24 PF13479.6 KXS09721.1 - 0.0002 21.1 0.0 0.29 10.8 0.0 3.4 3 0 0 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 KXS09721.1 - 0.0002 21.3 0.0 0.91 9.4 0.0 3.1 3 0 0 3 3 2 2 RsgA GTPase AAA_28 PF13521.6 KXS09721.1 - 0.00024 21.4 0.3 2.5 8.3 0.0 4.3 3 0 0 3 3 3 1 AAA domain AAA_3 PF07726.11 KXS09721.1 - 0.00033 20.5 0.0 0.51 10.2 0.0 3.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 KXS09721.1 - 0.00037 21.0 0.2 0.15 12.6 0.0 3.3 3 0 0 3 3 2 1 ABC transporter RuvB_N PF05496.12 KXS09721.1 - 0.00039 20.2 5.5 0.1 12.4 0.0 4.5 5 1 0 5 5 4 1 Holliday junction DNA helicase RuvB P-loop domain AAA_23 PF13476.6 KXS09721.1 - 0.00064 20.3 10.4 0.64 10.5 0.9 4.7 5 0 0 5 5 4 1 AAA domain AAA_30 PF13604.6 KXS09721.1 - 0.002 17.9 2.4 1.9 8.2 0.0 4.0 3 1 0 3 3 3 1 AAA domain DUF815 PF05673.13 KXS09721.1 - 0.0025 17.0 0.0 1.5 7.9 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) T2SSE PF00437.20 KXS09721.1 - 0.0027 16.8 0.1 0.026 13.6 0.0 2.7 2 2 0 2 2 2 1 Type II/IV secretion system protein AAA_25 PF13481.6 KXS09721.1 - 0.0051 16.4 0.1 0.84 9.2 0.0 3.2 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 KXS09721.1 - 0.0067 16.4 0.2 5.7 6.8 0.0 3.2 3 0 0 3 3 3 0 NTPase Torsin PF06309.11 KXS09721.1 - 0.01 15.9 0.1 0.25 11.5 0.0 2.5 2 0 0 2 2 2 0 Torsin DUF87 PF01935.17 KXS09721.1 - 0.01 15.9 4.2 0.25 11.4 0.0 3.8 4 0 0 4 4 4 0 Helicase HerA, central domain ResIII PF04851.15 KXS09721.1 - 0.02 14.9 0.0 0.94 9.4 0.0 3.0 3 0 0 3 3 2 0 Type III restriction enzyme, res subunit SRP54 PF00448.22 KXS09721.1 - 0.032 13.8 0.0 4.1 7.0 0.0 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain zf-C4H2 PF10146.9 KXS09721.1 - 0.036 14.4 6.7 0.23 11.8 3.1 2.3 2 0 0 2 2 2 0 Zinc finger-containing protein AAA_19 PF13245.6 KXS09721.1 - 0.04 14.3 0.1 3 8.2 0.1 3.1 3 1 0 3 3 2 0 AAA domain DNA_pol3_delta2 PF13177.6 KXS09721.1 - 0.052 13.3 0.0 0.24 11.2 0.0 2.1 2 0 0 2 2 1 0 DNA polymerase III, delta subunit AAA_29 PF13555.6 KXS09721.1 - 0.052 13.3 0.0 16 5.3 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain Bac_DnaA PF00308.18 KXS09721.1 - 0.067 13.0 0.0 6.5 6.5 0.0 3.0 3 0 0 3 3 2 0 Bacterial dnaA protein TIP49 PF06068.13 KXS09721.1 - 0.072 12.3 3.1 3.8 6.6 0.0 3.1 4 0 0 4 4 4 0 TIP49 P-loop domain MMR_HSR1 PF01926.23 KXS09721.1 - 0.093 12.8 0.0 19 5.4 0.0 3.0 2 0 0 2 2 2 0 50S ribosome-binding GTPase PduV-EutP PF10662.9 KXS09721.1 - 0.17 11.6 0.0 2 8.2 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation BLOC1_2 PF10046.9 KXS09721.1 - 0.94 9.8 6.0 0.32 11.3 1.6 2.6 2 0 0 2 2 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 RRN3 PF05327.11 KXS09721.1 - 1 7.8 6.6 1.9 7.0 6.6 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 ADIP PF11559.8 KXS09721.1 - 5.3 7.1 16.3 0.08 13.0 8.2 2.1 2 0 0 2 2 1 0 Afadin- and alpha -actinin-Binding SKA1 PF07160.12 KXS09721.1 - 5.3 6.8 10.9 0.23 11.3 4.2 1.9 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 V_ATPase_I PF01496.19 KXS09721.1 - 8 4.2 5.5 3.4 5.4 1.8 1.9 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Fib_alpha PF08702.10 KXS09721.1 - 8.9 6.5 7.0 10 6.3 2.2 2.7 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family F-box-like PF12937.7 KXS09722.1 - 1.6e-06 27.9 0.1 2.5e-06 27.3 0.1 1.3 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXS09722.1 - 8.1e-06 25.6 0.0 1.6e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 F-box domain ADH_zinc_N_2 PF13602.6 KXS09724.1 - 6.5e-20 72.5 0.0 1.1e-19 71.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KXS09724.1 - 9e-12 45.1 0.1 1.6e-11 44.3 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXS09724.1 - 2.4e-06 27.4 0.1 7.2e-06 25.9 0.0 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain DUF2855 PF11017.8 KXS09724.1 - 0.00036 20.4 0.0 0.017 14.9 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2855) ADH_N_2 PF16884.5 KXS09724.1 - 0.00075 19.4 0.1 0.0027 17.6 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain of oxidoreductase DapB_N PF01113.20 KXS09724.1 - 0.049 13.8 0.0 0.085 13.0 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus DHFR_2 PF06442.11 KXS09724.1 - 0.084 12.7 0.1 0.2 11.5 0.1 1.6 1 0 0 1 1 1 0 R67 dihydrofolate reductase ADH_zinc_N PF00107.26 KXS09725.1 - 2.1e-10 40.7 0.0 3e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXS09725.1 - 2.8e-06 28.4 0.0 4.1e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF2855 PF11017.8 KXS09725.1 - 0.015 15.0 0.0 0.02 14.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2855) Eno-Rase_NADH_b PF12242.8 KXS09725.1 - 0.073 12.8 0.3 1.5 8.7 0.0 2.3 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF5522 PF17653.1 KXS09726.1 - 5.4e-23 80.7 6.5 7e-23 80.3 6.5 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5522) Na_H_Exchanger PF00999.21 KXS09727.1 - 4.8e-46 157.3 38.9 6.2e-46 156.9 38.9 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Ribosomal_L27 PF01016.19 KXS09728.1 - 1e-29 102.4 0.6 1.1e-29 102.3 0.6 1.0 1 0 0 1 1 1 1 Ribosomal L27 protein RHD3 PF05879.12 KXS09730.1 - 1.6e-216 721.0 1.6 2.2e-193 644.4 0.4 2.0 1 1 1 2 2 2 2 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.19 KXS09730.1 - 8.3e-06 25.3 0.1 1.7e-05 24.2 0.1 1.5 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain MMR_HSR1 PF01926.23 KXS09730.1 - 1.3e-05 25.2 0.0 3.8e-05 23.7 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 KXS09730.1 - 4.5e-05 23.6 0.3 0.00016 21.8 0.0 2.1 2 0 0 2 2 2 1 Dynamin family AAA_28 PF13521.6 KXS09730.1 - 0.0037 17.5 0.2 0.027 14.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain MIEAP PF16026.5 KXS09730.1 - 0.11 12.7 2.6 0.21 11.8 2.6 1.4 1 0 0 1 1 1 0 Mitochondria-eating protein Septin PF00735.18 KXS09730.1 - 0.12 11.6 0.1 0.32 10.2 0.1 1.7 1 0 0 1 1 1 0 Septin KxDL PF10241.9 KXS09730.1 - 0.22 11.8 6.0 0.82 10.0 1.1 3.3 3 0 0 3 3 3 0 Uncharacterized conserved protein PIN_8 PF18476.1 KXS09730.1 - 0.73 9.7 10.3 0.48 10.2 5.8 2.6 2 1 1 3 3 3 0 PIN like domain FliG_C PF01706.16 KXS09730.1 - 1.4 9.1 5.7 15 5.8 0.6 2.6 1 1 1 2 2 2 0 FliG C-terminal domain NPA PF16469.5 KXS09730.1 - 1.8 9.1 5.1 23 5.6 2.4 2.9 1 1 2 3 3 3 0 Nematode polyprotein allergen ABA-1 AA_permease_2 PF13520.6 KXS09731.1 - 9e-43 146.7 44.9 1.7e-42 145.7 44.9 1.4 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXS09731.1 - 1.5e-17 63.3 34.3 1.8e-10 40.0 15.5 2.5 2 1 1 3 3 3 2 Amino acid permease DUF4506 PF14958.6 KXS09732.1 - 0.00036 20.1 0.0 0.00059 19.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4506) Aminotran_1_2 PF00155.21 KXS09733.1 - 8.1e-27 94.3 0.0 2.1e-19 70.0 0.0 2.0 2 0 0 2 2 2 2 Aminotransferase class I and II CPSase_sm_chain PF00988.22 KXS09734.1 - 5.8e-44 149.0 0.0 1.1e-43 148.2 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 KXS09734.1 - 2.7e-35 121.9 0.0 3.6e-35 121.5 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KXS09734.1 - 0.0042 16.9 0.2 0.4 10.4 0.2 2.3 1 1 0 1 1 1 1 Peptidase C26 Zip PF02535.22 KXS09735.1 - 1.7e-26 93.3 21.7 7.4e-25 87.9 21.7 3.1 1 1 0 1 1 1 1 ZIP Zinc transporter DUF4400 PF14348.6 KXS09735.1 - 0.03 13.8 0.1 0.053 13.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4400) Sec10 PF07393.11 KXS09736.1 - 2e-114 383.6 0.0 2.4e-114 383.3 0.0 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 F-box PF00646.33 KXS09736.1 - 0.0037 17.1 0.0 0.0073 16.2 0.0 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KXS09736.1 - 0.015 15.2 0.0 0.033 14.1 0.0 1.6 1 0 0 1 1 1 0 F-box-like gag-asp_proteas PF13975.6 KXS09737.1 - 0.13 12.8 0.0 0.59 10.7 0.0 2.1 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease dUTPase PF00692.19 KXS09737.1 - 0.14 11.9 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 dUTPase NUDE_C PF04880.13 KXS09737.1 - 0.95 9.9 6.7 3.9 7.9 6.7 2.1 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region Ank_2 PF12796.7 KXS09738.1 - 2.6e-19 69.6 1.9 1.8e-10 41.3 0.2 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KXS09738.1 - 4.2e-14 52.3 10.8 0.00019 21.8 0.3 4.2 3 1 1 4 4 4 4 Ankyrin repeat Ank_3 PF13606.6 KXS09738.1 - 5.9e-14 50.8 1.7 0.0059 17.0 0.1 4.2 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 KXS09738.1 - 2.1e-12 47.3 3.2 0.0014 19.2 0.1 3.9 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXS09738.1 - 1.1e-10 41.5 4.7 0.002 18.4 0.4 3.3 2 1 1 3 3 3 3 Ankyrin repeats (many copies) PDZ_3 PF17815.1 KXS09738.1 - 0.15 11.9 0.0 0.25 11.2 0.0 1.4 1 1 0 1 1 1 0 PDZ domain EH_Signature PF15611.6 KXS09739.1 - 0.14 11.5 0.3 5.5 6.3 0.1 2.1 2 0 0 2 2 2 0 EH_Signature domain DAP10 PF07213.11 KXS09740.1 - 0.0024 17.8 0.1 0.006 16.5 0.1 1.6 1 0 0 1 1 1 1 DAP10 membrane protein Cadherin_C_2 PF16492.5 KXS09740.1 - 0.041 14.6 4.9 0.29 11.9 0.3 2.9 2 1 0 2 2 2 0 Cadherin cytoplasmic C-terminal Rax2 PF12768.7 KXS09740.1 - 0.24 10.9 0.1 0.4 10.1 0.1 1.3 1 0 0 1 1 1 0 Cortical protein marker for cell polarity CAF1 PF04857.20 KXS09741.1 - 1.2e-56 192.2 0.0 1.7e-56 191.8 0.0 1.2 1 0 0 1 1 1 1 CAF1 family ribonuclease RNA_bind PF08675.11 KXS09741.1 - 0.12 12.4 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 RNA binding domain SH3_9 PF14604.6 KXS09742.1 - 4.4e-06 26.5 0.0 7.1e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXS09742.1 - 0.00011 21.7 0.0 0.00018 21.0 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KXS09742.1 - 0.088 12.5 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Variant SH3 domain RGS PF00615.19 KXS09743.1 - 0.00026 21.3 0.0 0.00049 20.3 0.0 1.4 1 0 0 1 1 1 1 Regulator of G protein signaling domain Peptidase_U4 PF03419.13 KXS09743.1 - 0.4 9.9 2.6 0.72 9.1 2.6 1.4 1 0 0 1 1 1 0 Sporulation factor SpoIIGA Cas9_Topo PF17894.1 KXS09744.1 - 0.17 12.0 0.0 0.28 11.2 0.0 1.3 1 0 0 1 1 1 0 Topo homolgy domain in CRISPR-associated endonuclease Cas9 F-box-like PF12937.7 KXS09746.1 - 8.5e-05 22.4 1.3 0.00017 21.4 1.3 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXS09746.1 - 0.0014 18.4 0.6 0.0014 18.4 0.6 1.9 2 0 0 2 2 2 1 F-box domain DUF5559 PF17714.1 KXS09746.1 - 5.4 6.9 9.9 1.5 8.7 3.7 2.7 3 0 0 3 3 3 0 Family of unknown function (DUF5559) Dala_Dala_lig_C PF07478.13 KXS09747.1 - 3.3e-15 56.2 0.0 4.3e-15 55.8 0.0 1.2 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus GARS_A PF01071.19 KXS09747.1 - 1.7e-07 31.2 0.0 3e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_3 PF02655.14 KXS09747.1 - 1.2e-05 25.4 0.0 3e-05 24.1 0.0 1.7 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.6 KXS09747.1 - 0.0001 21.9 0.0 0.00065 19.3 0.0 2.2 2 1 0 2 2 2 1 ATP-grasp domain ATP-grasp PF02222.22 KXS09747.1 - 0.00031 20.4 0.0 0.00055 19.6 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain His_biosynth PF00977.21 KXS09748.1 - 2.2e-46 158.2 0.0 1e-45 156.0 0.0 2.1 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.28 KXS09748.1 - 1.4e-15 57.6 0.0 2.2e-15 56.9 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 KXS09748.1 - 2.9e-07 30.3 0.0 7.5e-07 28.9 0.0 1.6 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain SNO PF01174.19 KXS09748.1 - 8.7e-06 25.7 0.0 0.0047 16.8 0.0 2.3 2 0 0 2 2 2 2 SNO glutamine amidotransferase family SOR_SNZ PF01680.17 KXS09748.1 - 0.055 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 SOR/SNZ family ThiG PF05690.14 KXS09748.1 - 0.067 12.5 0.0 0.14 11.4 0.0 1.5 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG NMO PF03060.15 KXS09748.1 - 0.15 11.4 0.2 0.39 10.1 0.0 1.7 2 0 0 2 2 2 0 Nitronate monooxygenase Dus PF01207.17 KXS09748.1 - 0.19 10.8 0.0 0.43 9.6 0.0 1.5 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) Zwilch PF09817.9 KXS09749.1 - 0.012 14.2 0.0 0.017 13.6 0.0 1.1 1 0 0 1 1 1 0 RZZ complex, subunit zwilch TMEM18 PF14770.6 KXS09750.1 - 1.7e-09 37.7 4.7 1.4e-05 25.1 0.4 2.1 2 0 0 2 2 2 2 Transmembrane protein 18 Sec1 PF00995.23 KXS09754.1 - 7.4e-10 38.7 0.0 6.4e-08 32.3 0.0 2.1 2 0 0 2 2 2 2 Sec1 family DUF3017 PF11222.8 KXS09754.1 - 0.16 12.2 0.8 5.3 7.4 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3017) peroxidase PF00141.23 KXS09755.1 - 1e-22 80.9 0.0 2.1e-22 79.9 0.0 1.5 1 1 0 1 1 1 1 Peroxidase Acetyltransf_1 PF00583.25 KXS09756.1 - 1.9e-06 28.1 0.0 3.2e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXS09756.1 - 8.8e-05 22.9 0.0 0.00013 22.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KXS09756.1 - 0.00023 21.1 0.0 0.00038 20.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KXS09756.1 - 0.0015 18.6 0.0 0.0029 17.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXS09756.1 - 0.042 13.8 0.0 0.079 12.9 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Polysacc_deac_1 PF01522.21 KXS09758.1 - 3.7e-18 65.6 0.0 6.3e-18 64.9 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase SWI-SNF_Ssr4 PF08549.10 KXS09758.1 - 2.2 6.8 4.0 3.1 6.3 4.0 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) WD40 PF00400.32 KXS09759.1 - 0.098 13.6 2.0 0.62 11.0 0.1 3.3 3 1 0 3 3 3 0 WD domain, G-beta repeat PQQ_3 PF13570.6 KXS09759.1 - 0.22 12.1 2.2 1.5 9.5 0.7 2.8 2 0 0 2 2 2 0 PQQ-like domain HEAT_2 PF13646.6 KXS09760.1 - 3.1e-37 126.8 1.1 2.5e-14 53.4 0.1 4.0 2 2 2 4 4 4 4 HEAT repeats HEAT_PBS PF03130.16 KXS09760.1 - 2.2e-29 99.1 0.0 7.7e-06 26.1 0.0 6.3 6 0 0 6 6 6 6 PBS lyase HEAT-like repeat HEAT PF02985.22 KXS09760.1 - 2e-08 33.8 0.1 0.013 15.7 0.0 4.7 5 0 0 5 5 5 2 HEAT repeat HEAT_EZ PF13513.6 KXS09760.1 - 8.4e-06 26.2 0.1 0.34 11.5 0.0 3.7 2 2 1 3 3 3 2 HEAT-like repeat Arm PF00514.23 KXS09760.1 - 0.022 14.8 0.0 3 8.0 0.0 2.7 2 1 0 2 2 2 0 Armadillo/beta-catenin-like repeat Vitellogenin_N PF01347.22 KXS09760.1 - 0.03 12.7 0.0 4.4 5.6 0.0 2.2 2 0 0 2 2 2 0 Lipoprotein amino terminal region COQ7 PF03232.13 KXS09761.1 - 8.9e-76 253.4 0.4 1.1e-75 253.1 0.4 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Ferritin PF00210.24 KXS09761.1 - 0.0048 16.8 0.4 0.12 12.3 0.0 2.1 2 0 0 2 2 2 1 Ferritin-like domain Metal_hydrol PF10118.9 KXS09761.1 - 0.11 12.2 0.1 0.15 11.7 0.1 1.3 1 0 0 1 1 1 0 Predicted metal-dependent hydrolase zf_UBZ PF18439.1 KXS09762.1 - 0.011 15.3 2.0 1 9.0 0.1 2.6 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-Di19 PF05605.12 KXS09762.1 - 0.061 13.6 10.2 0.9 9.9 4.5 2.5 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding TRAF6_Z2 PF18048.1 KXS09762.1 - 0.23 11.6 5.7 2.5 8.3 0.1 3.4 3 0 0 3 3 3 0 TNF receptor-associated factor 6 zinc finger 2 UVR PF02151.19 KXS09762.1 - 0.39 10.5 3.7 9.6 6.1 0.2 2.6 2 0 0 2 2 2 0 UvrB/uvrC motif zf-ribbon_3 PF13248.6 KXS09762.1 - 0.87 9.1 5.2 5.4 6.6 0.2 3.3 3 0 0 3 3 3 0 zinc-ribbon domain FAM72 PF14976.6 KXS09763.1 - 1.2e-06 28.7 1.4 1.2e-06 28.7 1.4 2.8 3 0 0 3 3 3 1 FAM72 protein zf-C2HC5 PF06221.13 KXS09763.1 - 1.4 8.9 11.3 1.2 9.2 0.2 2.4 2 0 0 2 2 2 0 Putative zinc finger motif, C2HC5-type Desulfoferrod_N PF06397.12 KXS09764.1 - 1.1 9.0 3.2 0.79 9.4 0.5 2.0 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain CDP-OH_P_transf PF01066.21 KXS09766.1 - 4e-11 43.5 0.6 4e-11 43.5 0.6 2.2 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Solute_trans_a PF03619.16 KXS09767.1 - 9.7e-07 28.6 0.2 1.2e-06 28.3 0.2 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Solute_trans_a PF03619.16 KXS09768.1 - 2.9e-46 158.2 9.4 3.2e-46 158.0 9.4 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Rhodanese PF00581.20 KXS09769.1 - 1.3e-32 112.4 0.0 8.6e-16 58.4 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain AMP-binding PF00501.28 KXS09769.1 - 0.061 11.9 0.0 4.9 5.6 0.0 2.1 2 0 0 2 2 2 0 AMP-binding enzyme Rhodanese PF00581.20 KXS09770.1 - 1.3e-17 64.3 0.0 1.3e-08 35.4 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain Na_H_Exchanger PF00999.21 KXS09771.1 - 4.5e-48 164.0 29.0 5.5e-48 163.7 29.0 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Pkinase PF00069.25 KXS09772.1 - 3.2e-62 210.3 0.0 3.9e-62 210.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS09772.1 - 1e-24 87.2 0.0 1.4e-24 86.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXS09772.1 - 0.00049 20.1 0.8 0.0015 18.5 0.2 2.0 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KXS09772.1 - 0.01 15.2 0.0 0.015 14.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KXS09772.1 - 0.018 13.9 0.0 0.026 13.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 KXS09772.1 - 0.044 13.4 0.9 0.054 13.1 0.0 1.6 2 0 0 2 2 2 0 RIO1 family YrbL-PhoP_reg PF10707.9 KXS09772.1 - 0.074 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Acetyltransf_1 PF00583.25 KXS09775.1 - 7.9e-16 58.3 0.0 1.9e-15 57.1 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXS09775.1 - 2.3e-08 34.3 0.0 4.6e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KXS09775.1 - 0.00011 22.1 0.0 0.00019 21.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DOMON PF03351.17 KXS09777.1 - 1.4e-12 47.9 0.2 2.6e-12 47.0 0.2 1.4 1 0 0 1 1 1 1 DOMON domain Cytochrom_B561 PF03188.16 KXS09777.1 - 1.6e-12 47.8 8.0 2.9e-12 46.9 8.0 1.4 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF2427 PF10348.9 KXS09777.1 - 4.6e-09 36.0 2.6 1.1e-08 34.8 2.6 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF2427) CDH-cyt PF16010.5 KXS09777.1 - 0.00022 21.0 0.0 0.00039 20.2 0.0 1.3 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase DUF4079 PF13301.6 KXS09777.1 - 0.011 15.9 2.5 0.041 14.1 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4079) Peptidase_U4 PF03419.13 KXS09777.1 - 0.074 12.3 1.7 0.13 11.5 1.7 1.3 1 0 0 1 1 1 0 Sporulation factor SpoIIGA Ni_hydr_CYTB PF01292.20 KXS09777.1 - 4.3 6.9 15.0 1.7 8.2 9.4 2.8 2 1 1 3 3 3 0 Prokaryotic cytochrome b561 CPBP PF02517.16 KXS09777.1 - 4.9 7.6 7.3 3 8.3 1.5 3.0 4 0 0 4 4 4 0 CPBP intramembrane metalloprotease ANAPC3 PF12895.7 KXS09778.1 - 1.4e-13 50.8 23.8 7.3e-06 26.1 0.1 4.7 3 1 1 4 4 4 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 KXS09778.1 - 1.9e-10 41.1 9.7 1.3e-05 25.6 1.3 5.3 4 2 1 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 KXS09778.1 - 8.4e-06 26.3 12.4 0.18 12.5 0.5 5.1 4 2 2 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.6 KXS09778.1 - 9.6e-06 25.7 2.4 0.00049 20.2 0.5 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 KXS09778.1 - 1.3e-05 25.6 6.5 0.57 11.1 0.1 6.8 5 2 2 7 7 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 KXS09778.1 - 0.00017 21.4 2.9 0.59 10.3 0.0 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 KXS09778.1 - 0.00021 21.1 28.6 0.07 13.3 0.0 7.8 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_6 PF13174.6 KXS09778.1 - 0.00044 20.7 11.2 3.2 8.6 0.0 6.1 7 0 0 7 7 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 KXS09778.1 - 0.0016 18.7 9.7 0.83 10.0 0.0 5.1 4 2 1 5 5 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 KXS09778.1 - 0.0023 18.0 10.9 1.4 9.3 0.4 5.7 5 0 0 5 5 5 1 Tetratricopeptide repeat SRP_TPR_like PF17004.5 KXS09778.1 - 0.015 15.3 0.1 0.015 15.3 0.1 4.2 2 2 2 4 4 4 0 Putative TPR-like repeat PPR PF01535.20 KXS09778.1 - 0.044 14.0 1.4 6.6 7.2 0.0 4.2 7 0 0 7 7 3 0 PPR repeat FMN_red PF03358.15 KXS09778.1 - 0.045 13.5 0.0 0.096 12.4 0.0 1.5 1 0 0 1 1 1 0 NADPH-dependent FMN reductase C_LFY_FLO PF17538.2 KXS09778.1 - 0.052 13.0 1.1 0.16 11.4 1.1 1.8 1 1 0 1 1 1 0 DNA Binding Domain (C-terminal) Leafy/Floricaula TPR_17 PF13431.6 KXS09778.1 - 0.14 12.6 2.9 4.2 8.0 0.0 4.0 3 1 1 4 4 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 KXS09778.1 - 0.42 10.5 16.9 1.6 8.7 0.2 6.1 7 0 0 7 7 7 0 Tetratricopeptide repeat HA2 PF04408.23 KXS09779.1 - 1.3e-18 67.2 0.3 5.9e-18 65.1 0.0 2.3 2 0 0 2 2 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KXS09779.1 - 6.3e-13 49.0 0.0 1.5e-12 47.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain dsrm PF00035.26 KXS09779.1 - 3.6e-10 40.4 0.1 0.00025 21.7 0.0 4.2 3 1 0 3 3 3 2 Double-stranded RNA binding motif OB_NTP_bind PF07717.16 KXS09779.1 - 6.5e-05 23.2 0.0 0.00019 21.8 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 KXS09779.1 - 0.0004 20.2 0.0 0.001 18.9 0.0 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase Dicer_dimer PF03368.14 KXS09779.1 - 0.00069 19.7 0.0 0.9 9.7 0.0 2.9 2 0 0 2 2 2 2 Dicer dimerisation domain AAA_19 PF13245.6 KXS09779.1 - 0.0011 19.4 0.0 0.0022 18.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 KXS09779.1 - 0.012 15.5 0.0 0.028 14.3 0.0 1.6 1 0 0 1 1 1 0 NACHT domain T2SSE PF00437.20 KXS09779.1 - 0.014 14.5 0.0 0.035 13.2 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein ResIII PF04851.15 KXS09779.1 - 0.026 14.5 0.0 0.062 13.3 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit SRP54 PF00448.22 KXS09779.1 - 0.056 13.1 0.1 0.22 11.1 0.0 1.9 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain cobW PF02492.19 KXS09779.1 - 0.18 11.4 0.1 1.5 8.4 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Zn_clus PF00172.18 KXS09780.1 - 1.2e-06 28.5 9.0 1.9e-06 27.9 9.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GST_C PF00043.25 KXS09781.1 - 1.5e-09 37.9 0.0 3e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KXS09781.1 - 7.1e-09 35.8 0.0 1.2e-08 35.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KXS09781.1 - 1e-08 35.4 0.0 2.2e-08 34.3 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KXS09781.1 - 1.5e-07 31.3 0.0 2.9e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KXS09781.1 - 0.0015 18.8 0.0 0.0027 18.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_5 PF16865.5 KXS09781.1 - 0.12 13.0 0.0 0.21 12.1 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain KxDL PF10241.9 KXS09782.1 - 2.8e-13 49.9 0.0 4e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein CBM_20 PF00686.19 KXS09784.1 - 6.1e-11 42.1 0.0 1.9e-10 40.5 0.0 1.8 1 1 0 1 1 1 1 Starch binding domain DUF1929 PF09118.11 KXS09784.1 - 3e-05 24.2 0.0 7.4e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) DSPc PF00782.20 KXS09784.1 - 3.6e-05 23.6 0.0 5.9e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KXS09784.1 - 0.00031 20.8 0.4 0.0006 19.9 0.4 1.4 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 KXS09784.1 - 0.0016 18.0 0.1 0.0035 16.9 0.1 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 KXS09784.1 - 0.05 13.3 0.0 0.092 12.4 0.0 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Stc1 PF12898.7 KXS09786.1 - 0.0029 18.1 1.6 0.032 14.8 2.5 2.0 1 1 1 2 2 2 2 Stc1 domain RNA_POL_M_15KD PF02150.16 KXS09786.1 - 0.27 11.2 5.2 35 4.4 0.0 3.1 2 1 0 2 2 2 0 RNA polymerases M/15 Kd subunit A2L_zn_ribbon PF08792.10 KXS09786.1 - 3.2 7.6 7.7 21 5.0 1.0 3.2 3 0 0 3 3 3 0 A2L zinc ribbon domain MRP-S28 PF10213.9 KXS09787.1 - 1e-20 74.5 1.2 1.3e-15 57.9 0.1 2.8 3 0 0 3 3 3 2 Mitochondrial ribosomal subunit protein Ins_P5_2-kin PF06090.12 KXS09788.1 - 2.6e-26 92.9 0.0 3e-26 92.7 0.0 1.0 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase Dimer_Tnp_hAT PF05699.14 KXS09789.1 - 1.7e-11 43.7 0.0 1.8e-11 43.6 0.0 1.0 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region PhyH PF05721.13 KXS09790.1 - 4.8e-22 79.3 0.0 6e-22 78.9 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) SIT PF15330.6 KXS09790.1 - 0.039 14.4 0.0 0.059 13.8 0.0 1.3 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT DUF1479 PF07350.12 KXS09790.1 - 0.14 10.9 0.0 0.22 10.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1479) DNA_binding_1 PF01035.20 KXS09791.1 - 2.9e-27 94.6 0.9 3.7e-27 94.2 0.1 1.6 2 0 0 2 2 2 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Tcp11 PF05794.13 KXS09793.1 - 2.1e-59 201.8 0.0 2.6e-59 201.5 0.0 1.1 1 0 0 1 1 1 1 T-complex protein 11 PhnA_Zn_Ribbon PF08274.12 KXS09793.1 - 0.1 12.6 0.4 0.2 11.6 0.4 1.5 1 0 0 1 1 1 0 PhnA Zinc-Ribbon IcmF-related PF06761.12 KXS09793.1 - 0.1 12.0 0.0 0.27 10.7 0.0 1.6 1 0 0 1 1 1 0 Intracellular multiplication and human macrophage-killing MFS_1 PF07690.16 KXS09794.1 - 5.5e-52 176.8 48.7 1e-51 176.0 48.7 1.5 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KXS09794.1 - 5.8e-14 51.4 23.0 1e-13 50.6 22.9 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KXS09794.1 - 1.2e-08 34.2 10.1 8.9e-08 31.4 1.6 4.0 3 1 1 4 4 4 2 Sugar (and other) transporter Tmp39 PF10271.9 KXS09794.1 - 0.085 11.8 1.6 0.14 11.1 1.6 1.2 1 0 0 1 1 1 0 Putative transmembrane protein CrgA PF06781.12 KXS09794.1 - 7 6.8 0.0 7 6.8 0.0 4.2 2 2 4 6 6 6 0 Cell division protein CrgA MFS_1 PF07690.16 KXS09795.1 - 5.5e-46 157.1 61.2 5.5e-46 157.1 61.2 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KXS09795.1 - 3.3e-12 45.7 26.3 4.2e-12 45.3 26.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KXS09795.1 - 9.3e-09 34.6 13.3 9.3e-09 34.6 13.3 3.8 1 1 0 3 3 3 1 Sugar (and other) transporter DUF2627 PF11118.8 KXS09795.1 - 3.7 8.2 0.0 3.7 8.2 0.0 4.5 5 2 1 6 6 6 0 Protein of unknown function (DUF2627) F-box-like PF12937.7 KXS09796.1 - 0.015 15.2 0.1 0.062 13.2 0.1 2.0 2 0 0 2 2 2 0 F-box-like Dimer_Tnp_hAT PF05699.14 KXS09797.1 - 3.1e-15 55.7 0.0 4.2e-15 55.3 0.0 1.2 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region TC1 PF15063.6 KXS09797.1 - 0.14 12.1 0.0 0.31 10.9 0.0 1.6 2 0 0 2 2 2 0 Thyroid cancer protein 1 Reeler PF02014.16 KXS09798.1 - 9.8e-07 29.6 0.0 1.9e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 Reeler domain DUF4246 PF14033.6 KXS09799.1 - 9.1e-106 354.7 0.0 5.8e-105 352.0 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_5 PF13759.6 KXS09799.1 - 0.11 13.0 0.0 0.31 11.5 0.0 1.8 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase MFS_1 PF07690.16 KXS09800.1 - 1.7e-46 158.8 46.3 5e-30 104.6 8.5 3.4 3 1 0 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.13 KXS09800.1 - 3.7e-15 55.4 28.5 1.3e-14 53.6 28.5 1.7 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KXS09800.1 - 3.7e-11 42.6 10.3 3.7e-11 42.6 10.3 3.3 2 1 0 3 3 3 1 Sugar (and other) transporter zf-C2H2_4 PF13894.6 KXS09802.1 - 0.00074 20.1 0.2 0.0016 19.1 0.2 1.6 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2 PF00096.26 KXS09802.1 - 0.00083 19.7 0.6 0.0023 18.3 0.6 1.8 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-met PF12874.7 KXS09802.1 - 0.13 12.7 0.0 0.24 11.8 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KXS09802.1 - 0.16 12.3 0.0 0.35 11.2 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 KXS09802.1 - 0.23 11.4 1.4 0.5 10.3 1.4 1.6 1 0 0 1 1 1 0 zinc-finger of a C2HC-type GTP_EFTU PF00009.27 KXS09803.1 - 8.1e-67 224.5 0.3 1.2e-66 223.9 0.3 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 KXS09803.1 - 9.4e-30 102.9 0.0 4.8e-29 100.6 0.0 2.2 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 KXS09803.1 - 2.7e-23 81.8 0.0 9.6e-23 80.0 0.0 2.0 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KXS09803.1 - 7.6e-14 51.9 0.1 2.8e-13 50.0 0.1 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 KXS09803.1 - 8.8e-12 45.0 0.0 1.8e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 KXS09803.1 - 0.00014 21.9 0.2 0.00027 21.0 0.2 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase MFS_1 PF07690.16 KXS09804.1 - 2.8e-48 164.6 45.6 2.8e-48 164.6 45.6 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KXS09804.1 - 1.4e-19 70.0 20.6 2.1e-19 69.4 20.6 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KXS09804.1 - 6.3e-09 35.2 10.8 6.3e-09 35.2 10.8 3.4 2 1 2 4 4 4 1 Sugar (and other) transporter zf-MYND PF01753.18 KXS09807.1 - 5.8e-11 42.3 9.5 9.5e-11 41.6 9.5 1.5 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KXS09807.1 - 0.0077 16.5 7.0 0.0077 16.5 7.0 1.7 2 0 0 2 2 2 1 zf-MYND-like zinc finger, mRNA-binding MFS_1 PF07690.16 KXS09808.1 - 8.1e-50 169.7 49.7 8.1e-50 169.7 49.7 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KXS09808.1 - 3.2e-17 62.2 24.9 4.1e-17 61.8 24.9 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KXS09808.1 - 9.6e-13 47.8 9.8 4.4e-09 35.7 5.7 3.8 2 2 1 3 3 3 2 Sugar (and other) transporter OATP PF03137.20 KXS09808.1 - 0.034 12.5 17.8 0.31 9.3 15.6 2.7 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family AAA PF00004.29 KXS09809.1 - 2.3e-07 31.3 0.0 3.7e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NifW PF03206.14 KXS09809.1 - 0.2 12.2 0.0 13 6.4 0.0 2.3 2 0 0 2 2 2 0 Nitrogen fixation protein NifW Ank_2 PF12796.7 KXS09810.1 - 0.12 13.0 0.0 0.28 11.8 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) ABC_membrane PF00664.23 KXS09811.1 - 7.7e-72 242.2 18.8 3.5e-27 95.7 7.8 5.5 4 1 0 4 4 4 3 ABC transporter transmembrane region ABC_tran PF00005.27 KXS09811.1 - 2.2e-41 141.6 0.0 1e-20 74.7 0.0 3.6 3 0 0 3 3 3 2 ABC transporter AAA_16 PF13191.6 KXS09811.1 - 4e-11 43.6 2.0 4.3e-06 27.2 0.1 3.1 3 1 0 3 3 2 2 AAA ATPase domain SMC_N PF02463.19 KXS09811.1 - 2.8e-10 40.0 0.2 0.00076 19.0 0.0 4.6 5 0 0 5 5 5 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KXS09811.1 - 5.1e-07 29.7 0.1 0.021 14.7 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 KXS09811.1 - 2.3e-06 27.2 1.0 0.0099 15.6 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA PF00004.29 KXS09811.1 - 1.9e-05 25.1 0.3 2.4 8.6 0.0 4.2 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KXS09811.1 - 3.2e-05 24.2 1.1 0.031 14.5 0.2 3.9 3 1 0 3 3 3 1 AAA domain AAA_21 PF13304.6 KXS09811.1 - 0.00019 21.3 0.5 0.94 9.2 0.0 3.4 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system Zeta_toxin PF06414.12 KXS09811.1 - 0.00085 18.7 2.4 0.59 9.4 0.0 3.0 3 0 0 3 3 3 2 Zeta toxin AAA_33 PF13671.6 KXS09811.1 - 0.0013 18.9 1.0 0.61 10.2 0.1 3.7 3 0 0 3 3 3 1 AAA domain SbcCD_C PF13558.6 KXS09811.1 - 0.0013 18.9 0.3 1.5 9.1 0.0 3.1 3 0 0 3 3 2 1 Putative exonuclease SbcCD, C subunit MMR_HSR1 PF01926.23 KXS09811.1 - 0.0013 18.8 0.1 2.2 8.4 0.0 3.0 3 0 0 3 3 2 1 50S ribosome-binding GTPase DUF87 PF01935.17 KXS09811.1 - 0.0024 18.0 1.5 0.5 10.4 0.4 2.5 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_23 PF13476.6 KXS09811.1 - 0.0027 18.2 0.0 0.77 10.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KXS09811.1 - 0.0043 16.6 0.1 1.2 8.6 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_5 PF07728.14 KXS09811.1 - 0.0051 16.8 0.1 4.3 7.3 0.0 2.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 KXS09811.1 - 0.0092 15.6 1.3 0.64 9.6 0.1 3.0 3 0 0 3 3 2 1 AAA domain DUF815 PF05673.13 KXS09811.1 - 0.0093 15.1 0.1 0.79 8.8 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) MeaB PF03308.16 KXS09811.1 - 0.0095 14.9 0.2 0.45 9.4 0.0 2.3 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB ArsP_1 PF03773.13 KXS09811.1 - 0.011 14.9 0.4 0.011 14.9 0.4 2.8 4 0 0 4 4 4 0 Predicted permease NB-ARC PF00931.22 KXS09811.1 - 0.011 14.9 0.5 1.4 8.0 0.1 2.4 2 1 0 2 2 2 0 NB-ARC domain AAA_24 PF13479.6 KXS09811.1 - 0.014 15.2 0.0 4.4 7.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KXS09811.1 - 0.03 14.0 7.0 0.82 9.4 0.1 3.2 4 0 0 4 4 3 0 AAA domain ATP-synt_ab PF00006.25 KXS09811.1 - 0.033 13.8 0.0 4.4 6.9 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_18 PF13238.6 KXS09811.1 - 0.051 14.1 0.8 6.6 7.3 0.0 3.0 3 0 0 3 3 2 0 AAA domain TsaE PF02367.17 KXS09811.1 - 0.067 13.2 0.2 11 6.0 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATP_bind_1 PF03029.17 KXS09811.1 - 0.12 12.1 0.2 13 5.5 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Ank_2 PF12796.7 KXS09812.1 - 2.4e-10 40.9 0.0 1.4e-07 32.0 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KXS09812.1 - 1.1e-08 35.1 0.0 8.8e-05 22.8 0.0 4.3 4 0 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.6 KXS09812.1 - 1.1e-07 32.0 0.0 1e-06 28.9 0.1 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXS09812.1 - 3.8e-07 29.9 0.0 0.0014 18.9 0.0 3.7 4 0 0 4 4 4 1 Ankyrin repeat Ank_4 PF13637.6 KXS09812.1 - 9e-07 29.3 0.0 9.5e-06 26.1 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXS09813.1 - 0.00054 20.2 0.0 0.0014 18.9 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 KXS09813.1 - 0.0042 17.5 0.1 0.01 16.2 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeat PDZ_4 PF17816.1 KXS09813.1 - 0.027 14.9 0.1 0.041 14.3 0.1 1.3 1 0 0 1 1 1 0 PDZ domain Ank_2 PF12796.7 KXS09813.1 - 0.11 13.1 0.0 0.55 10.9 0.0 1.6 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) Asn_synthase PF00733.21 KXS09814.1 - 2.2e-12 47.3 0.1 9.3e-10 38.7 0.0 2.1 1 1 1 2 2 2 2 Asparagine synthase Mito_carr PF00153.27 KXS09815.1 - 1.6e-61 204.2 0.1 4.3e-19 68.2 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KXS09815.1 - 0.0025 17.0 2.3 0.37 9.9 0.0 3.5 3 1 1 4 4 4 2 Gammaproteobacterial serine protease BCIP PF13862.6 KXS09817.1 - 6e-32 111.1 0.0 7.2e-32 110.8 0.0 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein PMT PF02366.18 KXS09818.1 - 1.5e-59 201.6 17.4 2.7e-59 200.7 17.4 1.5 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 KXS09818.1 - 2.4e-48 164.4 5.3 2.4e-48 164.4 5.3 2.5 4 0 0 4 4 4 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 KXS09818.1 - 8.3e-13 48.6 0.0 3e-12 46.8 0.0 1.8 1 1 0 1 1 1 1 MIR domain DUF3151 PF11349.8 KXS09819.1 - 0.051 13.7 0.1 0.086 12.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3151) Methyltransf_10 PF05971.12 KXS09819.1 - 0.15 11.3 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 RNA methyltransferase BASP1 PF05466.12 KXS09820.1 - 0.88 9.5 5.4 1.1 9.3 5.4 1.1 1 0 0 1 1 1 0 Brain acid soluble protein 1 (BASP1 protein) ATG16 PF08614.11 KXS09821.1 - 3.6e-05 24.1 8.6 3.6e-05 24.1 8.6 8.8 2 2 6 8 8 8 4 Autophagy protein 16 (ATG16) Spc7 PF08317.11 KXS09821.1 - 3.7e-05 22.8 9.4 3.7e-05 22.8 9.4 8.6 4 2 5 9 9 9 4 Spc7 kinetochore protein EzrA PF06160.12 KXS09821.1 - 0.00034 18.9 4.8 0.00034 18.9 4.8 6.5 4 2 3 7 7 7 2 Septation ring formation regulator, EzrA HIP1_clath_bdg PF16515.5 KXS09821.1 - 0.00052 20.6 4.3 0.00052 20.6 4.3 13.2 5 2 7 13 13 13 3 Clathrin-binding domain of Huntingtin-interacting protein 1 MscS_porin PF12795.7 KXS09821.1 - 0.0053 16.3 11.0 0.0053 16.3 11.0 7.3 4 3 1 6 6 6 2 Mechanosensitive ion channel porin domain BRE1 PF08647.11 KXS09821.1 - 0.0068 16.5 8.0 0.019 15.0 1.1 9.0 6 4 2 8 8 8 4 BRE1 E3 ubiquitin ligase HisK_N PF09385.10 KXS09821.1 - 0.012 15.6 0.5 0.03 14.3 0.5 1.6 1 0 0 1 1 1 0 Histidine kinase N terminal Fib_alpha PF08702.10 KXS09821.1 - 0.18 12.0 40.3 2 8.6 2.9 7.2 4 2 3 7 7 7 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.12 KXS09821.1 - 0.4 10.7 63.6 0.84 9.7 3.8 10.1 5 2 5 12 12 12 0 Protein of unknown function (DUF1664) Golgin_A5 PF09787.9 KXS09821.1 - 4.7 6.6 110.6 0.029 13.8 15.6 7.2 4 2 2 7 7 7 0 Golgin subfamily A member 5 AA_permease_2 PF13520.6 KXS09822.1 - 3.8e-26 91.9 51.0 5.4e-26 91.4 51.0 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXS09822.1 - 8.2e-17 60.9 44.9 1.3e-16 60.3 44.9 1.2 1 0 0 1 1 1 1 Amino acid permease TMEM208_SND2 PF05620.11 KXS09822.1 - 0.073 12.9 2.4 3 7.6 0.0 3.2 2 0 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 Pkinase PF00069.25 KXS09823.1 - 1.4e-62 211.4 0.0 2.1e-62 210.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS09823.1 - 6.4e-37 127.2 0.0 1e-36 126.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.22 KXS09823.1 - 9e-21 73.5 17.8 1.1e-10 41.3 10.2 2.3 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) HR1 PF02185.16 KXS09823.1 - 6.3e-13 48.6 10.1 1.2e-06 28.6 0.5 3.8 3 0 0 3 3 3 2 Hr1 repeat Pkinase_C PF00433.24 KXS09823.1 - 1.2e-10 41.9 3.4 7e-10 39.5 3.4 2.5 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 KXS09823.1 - 0.00025 20.5 0.1 0.00082 18.8 0.0 1.8 2 0 0 2 2 2 1 Kinase-like C1_2 PF03107.16 KXS09823.1 - 0.0066 16.7 14.5 0.024 14.9 7.1 2.4 2 0 0 2 2 2 2 C1 domain Pkinase_fungal PF17667.1 KXS09823.1 - 0.014 14.2 0.0 0.014 14.2 0.0 3.0 2 1 0 2 2 2 0 Fungal protein kinase XAF1_C PF18608.1 KXS09823.1 - 2.7 7.6 5.1 1.2 8.7 1.1 2.5 2 1 1 3 3 3 0 XIAP-associated factor 1 C-terminal domain DJ-1_PfpI PF01965.24 KXS09824.1 - 9.4e-05 22.3 0.0 0.00017 21.4 0.0 1.5 2 0 0 2 2 2 1 DJ-1/PfpI family Phi_1 PF04674.12 KXS09825.1 - 3.8e-28 98.6 0.1 1e-27 97.2 0.1 1.7 1 1 0 1 1 1 1 Phosphate-induced protein 1 conserved region LRR_4 PF12799.7 KXS09825.1 - 0.00016 22.0 0.6 1.3 9.5 0.0 3.0 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXS09825.1 - 0.0038 17.0 0.4 0.41 10.4 0.0 2.4 2 0 0 2 2 2 2 Leucine rich repeat LRR_1 PF00560.33 KXS09825.1 - 0.2 12.3 2.6 2.8e+02 2.8 0.1 4.9 3 1 0 3 3 3 0 Leucine Rich Repeat Cys_Met_Meta_PP PF01053.20 KXS09826.1 - 6.4e-55 186.2 0.0 2.4e-54 184.3 0.0 1.9 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme MFS_1 PF07690.16 KXS09829.1 - 1.1e-23 83.7 60.6 2.5e-12 46.4 23.3 2.5 2 1 0 2 2 2 2 Major Facilitator Superfamily BCHF PF07284.11 KXS09829.1 - 0.071 13.1 0.3 0.91 9.5 0.1 2.5 2 0 0 2 2 2 0 2-vinyl bacteriochlorophyllide hydratase (BCHF) DNA_binding_1 PF01035.20 KXS09830.1 - 3.1e-27 94.5 0.0 5e-27 93.8 0.0 1.3 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Methyltransf_1N PF02870.15 KXS09830.1 - 0.054 14.3 0.0 0.087 13.6 0.0 1.5 1 0 0 1 1 1 0 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain 2CSK_N PF08521.10 KXS09830.1 - 0.15 12.1 0.0 0.22 11.6 0.0 1.2 1 0 0 1 1 1 0 Two-component sensor kinase N-terminal Rhodanese PF00581.20 KXS09831.1 - 7e-12 45.8 0.0 1.1e-11 45.2 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain HATPase_c PF02518.26 KXS09832.1 - 1.2e-26 93.4 0.1 1.5e-25 89.9 0.0 2.7 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KXS09832.1 - 2.5e-20 72.7 0.1 4.9e-20 71.8 0.1 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 KXS09832.1 - 1.8e-18 66.4 1.6 3.2e-18 65.5 0.1 2.4 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain Host_attach PF10116.9 KXS09832.1 - 0.009 16.6 0.6 0.026 15.1 0.0 2.1 2 0 0 2 2 2 1 Protein required for attachment to host cells PAS_4 PF08448.10 KXS09832.1 - 0.13 12.5 0.0 1.5 9.1 0.0 2.4 2 0 0 2 2 2 0 PAS fold Mis12 PF05859.12 KXS09832.1 - 0.14 12.2 0.0 14 5.7 0.0 2.8 3 0 0 3 3 3 0 Mis12 protein KLRAQ PF10205.9 KXS09833.1 - 0.0011 19.2 0.0 0.0016 18.6 0.0 1.2 1 0 0 1 1 1 1 Predicted coiled-coil domain-containing protein DEC-1_N PF04625.13 KXS09833.1 - 2.8 6.9 5.2 3.8 6.4 5.2 1.3 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region LRR_4 PF12799.7 KXS09834.1 - 1.9e-16 59.9 17.4 1.8e-06 28.2 2.1 3.5 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXS09834.1 - 2.5e-06 27.1 23.1 0.00023 20.8 2.6 3.9 1 1 1 3 3 3 3 Leucine rich repeat LRR_1 PF00560.33 KXS09834.1 - 0.0043 17.4 18.2 0.11 13.1 0.4 5.5 4 2 0 4 4 4 2 Leucine Rich Repeat SH3_2 PF07653.17 KXS09834.1 - 0.015 15.0 0.0 0.042 13.5 0.0 1.8 1 0 0 1 1 1 0 Variant SH3 domain SH3_9 PF14604.6 KXS09834.1 - 0.074 12.9 0.0 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 Variant SH3 domain SH3_1 PF00018.28 KXS09834.1 - 0.14 11.8 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 SH3 domain LRR_9 PF14580.6 KXS09834.1 - 0.4 10.2 1.0 0.88 9.1 0.6 1.7 1 1 0 1 1 1 0 Leucine-rich repeat Ank_2 PF12796.7 KXS09835.1 - 1e-06 29.2 0.8 0.00094 19.7 0.2 3.3 2 1 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXS09835.1 - 0.00011 22.7 1.2 0.33 11.6 0.3 3.8 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXS09835.1 - 0.0005 20.3 0.9 17 6.4 0.0 4.6 5 0 0 5 5 5 2 Ankyrin repeat DUF249 PF03158.13 KXS09835.1 - 0.067 12.9 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Multigene family 530 protein UPF0061 PF02696.14 KXS09837.1 - 3.2e-35 121.8 0.0 4.6e-35 121.3 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family RVT_1 PF00078.27 KXS09838.1 - 4.2e-11 42.8 0.0 9.2e-11 41.7 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RTC PF01137.21 KXS09839.1 - 1.2e-69 233.9 0.0 2.5e-69 232.9 0.0 1.5 1 1 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 KXS09839.1 - 2.2e-07 31.4 0.0 6.5e-07 29.8 0.0 1.8 2 0 0 2 2 2 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain F-box-like PF12937.7 KXS09842.1 - 0.0026 17.6 0.2 0.0052 16.7 0.2 1.5 1 0 0 1 1 1 1 F-box-like HABP4_PAI-RBP1 PF04774.15 KXS09844.1 - 2.8e-05 24.9 1.7 3.2e-05 24.8 1.7 1.1 1 0 0 1 1 1 1 Hyaluronan / mRNA binding family Class_IIIsignal PF04021.12 KXS09845.1 - 0.019 15.0 0.7 0.093 12.7 0.7 2.3 1 0 0 1 1 1 0 Class III signal peptide DUF3040 PF11239.8 KXS09845.1 - 0.56 10.5 11.5 2.5 8.4 2.1 3.5 4 1 1 5 5 5 0 Protein of unknown function (DUF3040) DUF2721 PF11026.8 KXS09845.1 - 4.2 7.3 6.7 1.5 8.7 1.2 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2721) Claudin_3 PF06653.11 KXS09845.1 - 9.1 6.2 8.5 3.4 7.6 0.1 2.8 3 0 0 3 3 3 0 Tight junction protein, Claudin-like DUF3382 PF11862.8 KXS09846.1 - 0.13 12.6 5.4 0.21 11.9 4.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3382) DUF1404 PF07185.11 KXS09847.1 - 0.68 9.6 7.6 1.5 8.5 0.4 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1404) SRP-alpha_N PF04086.13 KXS09849.1 - 0.089 12.7 4.5 0.11 12.4 4.5 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal SPATIAL PF15256.6 KXS09849.1 - 0.26 11.6 1.6 0.39 11.0 1.6 1.3 1 0 0 1 1 1 0 SPATIAL SOG2 PF10428.9 KXS09849.1 - 9.8 5.2 15.3 13 4.8 15.3 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein GCR1_C PF12550.8 KXS09851.1 - 1.5e-20 73.3 0.0 1.8e-20 73.1 0.0 1.1 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes IBB PF01749.20 KXS09851.1 - 0.015 15.7 0.4 0.019 15.4 0.4 1.2 1 0 0 1 1 1 0 Importin beta binding domain adh_short PF00106.25 KXS09852.1 - 3.4e-25 88.6 0.0 3.4e-20 72.3 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXS09852.1 - 1.5e-14 54.1 0.0 2.4e-13 50.2 0.0 2.0 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXS09852.1 - 5.8e-06 26.3 0.0 9.8e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 KR domain HEAT PF02985.22 KXS09852.1 - 0.11 12.8 0.0 0.35 11.3 0.0 1.8 1 0 0 1 1 1 0 HEAT repeat 3HCDH_N PF02737.18 KXS09852.1 - 0.13 12.2 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Kelch_3 PF13415.6 KXS09853.1 - 7.9e-23 80.2 31.7 2.3e-08 34.1 0.2 7.6 7 2 0 7 7 7 4 Galactose oxidase, central domain Kelch_5 PF13854.6 KXS09853.1 - 3.2e-22 78.0 7.4 5e-05 23.2 0.1 6.0 5 1 0 5 5 5 5 Kelch motif Kelch_4 PF13418.6 KXS09853.1 - 3.2e-20 71.9 27.3 2e-09 37.3 0.5 8.1 7 2 1 8 8 8 3 Galactose oxidase, central domain Kelch_6 PF13964.6 KXS09853.1 - 1.6e-12 47.2 16.1 3.8e-07 30.1 0.1 5.6 6 1 0 6 6 6 3 Kelch motif Kelch_1 PF01344.25 KXS09853.1 - 3.7e-11 42.4 3.7 6.4e-07 28.9 0.0 4.8 4 1 0 4 4 4 2 Kelch motif Kelch_2 PF07646.15 KXS09853.1 - 1.1e-08 34.7 5.7 0.0078 16.2 0.0 5.8 6 0 0 6 6 6 3 Kelch motif DUF1648 PF07853.11 KXS09860.1 - 4.1e-14 52.0 2.3 4.6e-14 51.8 0.2 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF1648) Protocadherin PF08374.11 KXS09860.1 - 0.022 14.8 0.1 0.072 13.1 0.0 1.7 2 0 0 2 2 2 0 Protocadherin zf-H2C2_2 PF13465.6 KXS09864.1 - 0.00016 21.9 11.8 0.00017 21.8 1.3 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 KXS09864.1 - 0.00018 21.8 2.9 0.0056 17.1 0.1 2.6 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXS09864.1 - 0.00033 21.2 1.7 0.0067 17.2 0.1 2.9 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KXS09864.1 - 0.0011 18.9 0.3 0.0036 17.3 0.3 1.9 1 0 0 1 1 1 1 C2H2-type zinc finger FA_hydroxylase PF04116.13 KXS09865.1 - 2.1e-22 79.9 9.6 2.1e-22 79.9 9.6 2.0 1 1 1 2 2 2 1 Fatty acid hydroxylase superfamily MFS_1 PF07690.16 KXS09866.1 - 0.0038 16.2 0.9 0.0038 16.2 0.9 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.16 KXS09867.1 - 1.6e-17 63.5 35.7 2.8e-17 62.7 30.9 2.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXS09867.1 - 0.0036 16.2 9.1 0.0036 16.2 9.1 2.7 2 1 0 2 2 2 1 Sugar (and other) transporter SBP_bac_6 PF13343.6 KXS09867.1 - 0.22 10.9 0.0 0.34 10.3 0.0 1.2 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein Mannosyl_trans3 PF11051.8 KXS09868.1 - 3.7e-44 151.1 0.0 9.6e-44 149.8 0.0 1.6 1 1 0 1 1 1 1 Mannosyltransferase putative Nucleotid_trans PF03407.16 KXS09868.1 - 0.16 11.9 0.5 0.36 10.8 0.5 1.5 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase EpuA PF11772.8 KXS09868.1 - 0.21 11.3 0.0 0.21 11.3 0.0 1.9 2 0 0 2 2 2 0 DNA-directed RNA polymerase subunit beta Gly_transf_sug PF04488.15 KXS09870.1 - 8.6e-10 39.1 0.1 1.4e-09 38.5 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Glyco_trans_1_2 PF13524.6 KXS09871.1 - 2e-05 24.9 0.1 4.5e-05 23.7 0.1 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 ATP-cone PF03477.16 KXS09871.1 - 0.39 11.3 1.9 1.1 9.9 0.1 2.5 3 0 0 3 3 3 0 ATP cone domain DUF5389 PF17364.2 KXS09874.1 - 0.065 13.3 0.1 0.12 12.5 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5389) PseudoU_synth_1 PF01416.20 KXS09875.1 - 6.8e-18 65.1 0.0 3.9e-17 62.7 0.0 2.3 3 0 0 3 3 3 1 tRNA pseudouridine synthase ETC_C1_NDUFA5 PF04716.14 KXS09876.1 - 1.5e-30 104.7 0.2 2.2e-30 104.2 0.2 1.3 1 0 0 1 1 1 1 ETC complex I subunit conserved region FATC PF02260.20 KXS09876.1 - 0.064 13.1 4.9 0.29 11.0 4.9 2.0 1 1 0 1 1 1 0 FATC domain Homeodomain PF00046.29 KXS09879.1 - 9.1e-20 70.3 3.5 5.1e-12 45.4 0.4 2.8 3 0 0 3 3 3 2 Homeodomain Homeobox_KN PF05920.11 KXS09879.1 - 4.4e-16 58.5 1.2 2.5e-10 40.1 0.2 2.6 2 0 0 2 2 2 2 Homeobox KN domain Homez PF11569.8 KXS09879.1 - 0.0003 20.2 0.1 0.0027 17.1 0.0 2.2 2 0 0 2 2 2 1 Homeodomain leucine-zipper encoding, Homez HTH_3 PF01381.22 KXS09879.1 - 0.00033 20.6 0.0 0.48 10.5 0.0 2.6 2 0 0 2 2 2 2 Helix-turn-helix YdaS_antitoxin PF15943.5 KXS09879.1 - 0.0042 16.9 0.1 3.9 7.4 0.0 2.5 2 0 0 2 2 2 2 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT DS PF01916.17 KXS09880.1 - 3.6e-118 394.0 0.0 4.2e-118 393.8 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase bZIP_1 PF00170.21 KXS09881.1 - 1.8e-06 27.9 9.6 4.5e-06 26.7 8.3 2.1 1 1 1 2 2 2 1 bZIP transcription factor CCD48 PF15799.5 KXS09881.1 - 6 5.1 12.2 0.041 12.2 1.2 2.2 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 48 Dimer_Tnp_hAT PF05699.14 KXS09885.1 - 1.5e-16 60.0 0.0 1.7e-16 59.8 0.0 1.1 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Prok-RING_2 PF14445.6 KXS09886.1 - 0.078 13.2 0.6 0.37 11.0 0.0 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 2 SH3_9 PF14604.6 KXS09887.1 - 0.072 13.0 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 Variant SH3 domain SDA1 PF05285.12 KXS09888.1 - 0.15 11.4 16.8 0.16 11.4 16.8 1.0 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 KXS09888.1 - 1.1 7.4 14.7 1.1 7.3 14.7 1.1 1 0 0 1 1 1 0 Nop14-like family PPP4R2 PF09184.11 KXS09888.1 - 3.1 7.3 11.8 3.7 7.1 11.8 1.2 1 0 0 1 1 1 0 PPP4R2 Sel1 PF08238.12 KXS09889.1 - 1.2e-40 137.1 8.2 1.8e-09 38.0 0.3 6.0 7 0 0 7 7 7 5 Sel1 repeat OrfB_Zn_ribbon PF07282.11 KXS09892.1 - 7.4e-08 32.2 2.8 1.4e-07 31.3 2.8 1.5 1 0 0 1 1 1 1 Putative transposase DNA-binding domain RecR PF02132.15 KXS09892.1 - 0.33 10.6 0.1 0.33 10.6 0.1 2.5 2 0 0 2 2 2 0 RecR protein DUF1062 PF06353.12 KXS09892.1 - 0.61 10.9 3.7 1.3 9.8 3.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1062) F-box PF00646.33 KXS09893.1 - 3e-08 33.3 0.4 6.1e-06 26.0 0.0 2.4 2 0 0 2 2 2 2 F-box domain F-box-like PF12937.7 KXS09893.1 - 1.7e-07 31.0 0.1 3.7e-07 29.9 0.1 1.6 1 0 0 1 1 1 1 F-box-like RRM_1 PF00076.22 KXS09894.1 - 2e-17 62.7 0.1 2.5e-17 62.4 0.1 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) adh_short PF00106.25 KXS09895.1 - 1.3e-28 99.8 0.4 2.2e-26 92.5 0.3 2.0 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXS09895.1 - 3.6e-18 66.0 0.2 2.7e-17 63.1 0.0 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXS09895.1 - 4.1e-07 30.1 0.2 6e-07 29.5 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXS09895.1 - 0.0034 16.9 0.0 0.0045 16.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Peptidase_S9_N PF02897.15 KXS09897.1 - 5.7e-65 219.7 0.3 7.8e-65 219.3 0.3 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 KXS09897.1 - 7.6e-54 182.4 0.0 1.8e-52 177.9 0.0 2.4 2 0 0 2 2 2 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 KXS09897.1 - 0.0036 17.0 0.0 0.0083 15.7 0.0 1.6 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PD40 PF07676.12 KXS09897.1 - 0.38 10.7 2.0 5.4 7.1 0.1 3.1 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Pyridox_ox_2 PF12900.7 KXS09898.1 - 1.1e-46 158.3 0.0 1.5e-46 157.9 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase FMN_bind_2 PF04299.12 KXS09898.1 - 0.025 14.3 0.0 0.046 13.4 0.0 1.5 1 1 0 1 1 1 0 Putative FMN-binding domain GATA PF00320.27 KXS09899.1 - 7.9e-13 47.8 3.7 7.9e-13 47.8 3.7 1.8 2 0 0 2 2 2 1 GATA zinc finger DUF2373 PF10180.9 KXS09900.1 - 4e-23 81.0 0.1 6.8e-23 80.3 0.1 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) RRM_1 PF00076.22 KXS09901.1 - 1.6e-23 82.3 0.1 2.1e-23 81.9 0.1 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KXS09901.1 - 0.00029 20.9 0.0 0.00037 20.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif RRM_3 PF08777.11 KXS09901.1 - 0.12 12.5 0.0 0.15 12.1 0.0 1.1 1 0 0 1 1 1 0 RNA binding motif EMP24_GP25L PF01105.24 KXS09902.1 - 3.4e-45 154.2 0.9 3.9e-45 154.0 0.9 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD PP28 PF10252.9 KXS09902.1 - 0.036 14.5 3.3 0.054 13.9 3.3 1.2 1 0 0 1 1 1 0 Casein kinase substrate phosphoprotein PP28 EMP24_GP25L PF01105.24 KXS09903.1 - 8.9e-39 133.3 0.1 1e-38 133.1 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF5125 PF17163.4 KXS09903.1 - 0.064 13.4 0.8 1.5 8.9 0.0 2.5 1 1 2 3 3 3 0 Domain of unknown function (DUF5125) ZZ PF00569.17 KXS09906.1 - 6.7e-08 32.2 6.2 1.3e-07 31.3 6.2 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.31 KXS09906.1 - 1.7e-06 28.1 0.9 4.2e-06 26.9 0.9 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain SWIRM PF04433.17 KXS09906.1 - 2.3e-05 24.6 0.0 6.3e-05 23.2 0.0 1.8 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-bind_6 PF13921.6 KXS09906.1 - 0.0035 17.6 0.7 0.0085 16.3 0.7 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain C1_2 PF03107.16 KXS09906.1 - 0.14 12.5 3.6 0.28 11.5 3.6 1.5 1 0 0 1 1 1 0 C1 domain Ribosomal_S26e PF01283.19 KXS09908.1 - 5.4e-51 171.6 6.1 6.7e-51 171.3 6.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S26e Carla_C4 PF01623.17 KXS09908.1 - 0.014 15.3 1.3 0.028 14.4 1.3 1.5 1 0 0 1 1 1 0 Carlavirus putative nucleic acid binding protein eRF1_1 PF03463.15 KXS09911.1 - 7.2e-50 168.3 0.3 1.2e-49 167.6 0.3 1.4 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.15 KXS09911.1 - 9e-28 97.2 0.2 1.4e-27 96.6 0.2 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 KXS09911.1 - 9.2e-19 68.0 0.0 2.3e-18 66.7 0.0 1.7 1 0 0 1 1 1 1 eRF1 domain 3 Ank_4 PF13637.6 KXS09913.1 - 3e-28 97.8 3.2 6.5e-14 52.1 0.1 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXS09913.1 - 2.4e-19 69.7 0.1 2.3e-11 44.1 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KXS09913.1 - 1.6e-18 66.2 3.7 8.3e-10 38.7 0.2 2.7 2 1 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 KXS09913.1 - 2e-17 63.0 1.0 4.7e-08 33.1 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXS09913.1 - 7.7e-16 56.6 0.4 1.9e-07 30.8 0.1 3.4 3 0 0 3 3 3 2 Ankyrin repeat Nitro_FeMo-Co PF02579.17 KXS09913.1 - 0.0021 18.4 0.1 0.0041 17.4 0.1 1.5 1 1 0 1 1 1 1 Dinitrogenase iron-molybdenum cofactor MFS_1 PF07690.16 KXS09914.1 - 6.8e-23 81.1 62.5 3.3e-14 52.6 36.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXS09914.1 - 0.0067 15.3 4.4 0.0067 15.3 4.4 4.2 1 1 3 4 4 4 4 Sugar (and other) transporter MFS_1 PF07690.16 KXS09916.1 - 1.4e-22 80.1 67.1 3.2e-13 49.3 37.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KXS09916.1 - 0.0034 16.0 13.7 0.0034 16.0 13.7 2.6 1 1 1 2 2 2 1 MFS/sugar transport protein Ldl_recept_a PF00057.18 KXS09917.1 - 0.1 12.8 0.1 0.19 12.0 0.1 1.3 1 0 0 1 1 1 0 Low-density lipoprotein receptor domain class A SF3A2 PF16835.5 KXS09918.1 - 5.4e-37 126.1 0.0 9.1e-37 125.3 0.0 1.4 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 KXS09918.1 - 4.8e-07 30.0 1.7 4.8e-07 30.0 1.7 1.9 2 0 0 2 2 2 1 Zinc-finger of C2H2 type CactinC_cactus PF09732.9 KXS09918.1 - 5.3e-06 26.4 0.4 1e-05 25.5 0.3 1.5 1 1 0 1 1 1 1 Cactus-binding C-terminus of cactin protein PRP4 PF08799.11 KXS09918.1 - 0.012 15.2 0.6 0.019 14.5 0.6 1.3 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like DUF5024 PF16427.5 KXS09918.1 - 0.062 13.6 0.0 0.16 12.3 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF5024) Amino_oxidase PF01593.24 KXS09919.1 - 0.00012 21.5 0.0 0.00012 21.5 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase PLAC8 PF04749.17 KXS09920.1 - 7.7e-19 68.5 1.4 9.1e-19 68.3 1.4 1.1 1 0 0 1 1 1 1 PLAC8 family Porph_ging PF09697.10 KXS09920.1 - 0.1 13.2 0.0 3.5 8.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (Porph_ging) Aminotran_5 PF00266.19 KXS09921.1 - 4.7e-46 157.4 0.0 5.7e-46 157.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V DUF2462 PF09495.10 KXS09922.1 - 3.5e-10 40.5 11.6 3.5e-10 40.5 11.6 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF2462) Sar8_2 PF03058.14 KXS09922.1 - 0.26 11.8 2.4 0.41 11.2 2.4 1.3 1 0 0 1 1 1 0 Sar8.2 family Lipase_3 PF01764.25 KXS09925.1 - 4.3e-12 46.1 0.0 6.3e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.7 KXS09925.1 - 0.034 13.9 0.0 0.81 9.4 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase family RIBIOP_C PF04950.12 KXS09926.1 - 1.5e-96 323.3 0.0 3.4e-96 322.1 0.0 1.6 2 0 0 2 2 2 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 KXS09926.1 - 2.9e-14 52.9 0.0 7.3e-14 51.6 0.0 1.7 1 0 0 1 1 1 1 AARP2CN (NUC121) domain ABC1 PF03109.16 KXS09927.1 - 1e-32 112.8 0.0 1.8e-32 112.0 0.0 1.4 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 KXS09927.1 - 0.025 14.5 0.1 0.62 9.9 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family WaaY PF06176.11 KXS09927.1 - 0.15 11.6 0.0 0.41 10.2 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide core biosynthesis protein (WaaY) ABC1 PF03109.16 KXS09928.1 - 7.5e-28 97.1 0.1 1.2e-27 96.4 0.1 1.4 1 0 0 1 1 1 1 ABC1 family Oxysterol_BP PF01237.18 KXS09931.1 - 1e-45 156.2 0.0 2.3e-44 151.8 0.0 2.1 1 1 0 1 1 1 1 Oxysterol-binding protein UPF0176_N PF17773.1 KXS09933.1 - 1e-05 25.8 0.0 2.4e-05 24.6 0.0 1.7 1 1 0 1 1 1 1 UPF0176 acylphosphatase like domain Rhodanese PF00581.20 KXS09933.1 - 1.1e-05 25.9 0.0 5.5e-05 23.6 0.0 2.0 2 0 0 2 2 2 1 Rhodanese-like domain Ssl1 PF04056.14 KXS09934.1 - 3.9e-64 216.0 0.0 7.1e-63 211.9 0.0 2.0 1 1 1 2 2 2 1 Ssl1-like VWA_2 PF13519.6 KXS09934.1 - 7.2e-13 49.1 0.0 1.4e-12 48.2 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain C1_4 PF07975.12 KXS09934.1 - 2.2e-07 31.0 10.1 2.2e-07 31.0 10.1 2.6 4 1 0 4 4 4 1 TFIIH C1-like domain DZR PF12773.7 KXS09934.1 - 0.0035 17.3 1.6 0.0035 17.3 1.6 2.4 1 1 1 2 2 2 1 Double zinc ribbon VWA PF00092.28 KXS09934.1 - 0.0095 16.2 0.0 0.026 14.8 0.0 1.7 1 1 0 1 1 1 1 von Willebrand factor type A domain zf-UBP PF02148.19 KXS09934.1 - 1.1 9.6 7.3 2.7 8.4 6.0 2.1 2 0 0 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein C1_2 PF03107.16 KXS09934.1 - 2.4 8.5 10.6 5.3 7.4 0.1 2.8 2 1 0 2 2 2 0 C1 domain DUF4956 PF16316.5 KXS09935.1 - 0.032 13.9 1.1 0.044 13.4 1.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4956) DUF4337 PF14235.6 KXS09935.1 - 0.15 12.2 2.1 0.19 11.8 2.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF202 PF02656.15 KXS09935.1 - 1.3 9.5 11.9 2.4 8.6 11.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF202) UBA PF00627.31 KXS09937.1 - 0.0078 16.1 0.1 0.084 12.8 0.0 2.2 2 0 0 2 2 2 1 UBA/TS-N domain PQQ_2 PF13360.6 KXS09938.1 - 6.8e-06 25.8 0.2 5.3e-05 22.9 0.1 2.2 2 0 0 2 2 2 1 PQQ-like domain PQQ PF01011.21 KXS09938.1 - 0.00011 21.9 0.8 0.68 10.0 0.0 3.4 3 0 0 3 3 3 2 PQQ enzyme repeat ANAPC4_WD40 PF12894.7 KXS09938.1 - 0.015 15.6 0.1 0.93 9.8 0.0 3.3 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain ABC_membrane PF00664.23 KXS09939.1 - 1.9e-115 385.2 24.4 2.3e-62 211.2 3.7 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KXS09939.1 - 2.1e-67 225.9 0.0 4.5e-34 117.9 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KXS09939.1 - 5.5e-17 62.0 0.0 1.7e-06 27.6 0.0 3.7 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KXS09939.1 - 2.4e-07 31.3 2.6 0.035 14.5 0.2 3.5 3 1 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 KXS09939.1 - 2.8e-07 30.9 0.5 0.088 13.1 0.0 4.1 3 2 0 3 3 3 2 AAA domain AAA_29 PF13555.6 KXS09939.1 - 2.8e-06 27.0 1.3 0.012 15.4 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Zeta_toxin PF06414.12 KXS09939.1 - 7.7e-06 25.3 0.3 0.081 12.2 0.0 3.2 3 0 0 3 3 3 2 Zeta toxin AAA_15 PF13175.6 KXS09939.1 - 1.1e-05 25.4 0.2 0.04 13.6 0.0 2.5 3 0 0 3 3 2 2 AAA ATPase domain AAA_30 PF13604.6 KXS09939.1 - 2e-05 24.4 2.7 0.12 12.1 0.2 3.6 2 2 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KXS09939.1 - 3e-05 24.0 0.0 0.23 11.4 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase ABC_ATPase PF09818.9 KXS09939.1 - 7.1e-05 21.8 1.1 0.26 10.1 0.1 2.6 3 0 0 3 3 3 2 Predicted ATPase of the ABC class G-alpha PF00503.20 KXS09939.1 - 0.0001 21.6 0.0 0.067 12.3 0.0 2.4 2 0 0 2 2 2 2 G-protein alpha subunit AAA_21 PF13304.6 KXS09939.1 - 0.00018 21.4 0.1 2.7 7.7 0.1 3.9 3 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_7 PF12775.7 KXS09939.1 - 0.00029 20.4 0.0 0.2 11.1 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region SbcCD_C PF13558.6 KXS09939.1 - 0.00051 20.2 3.8 0.57 10.5 0.3 4.0 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.6 KXS09939.1 - 0.0012 19.0 0.0 2.5 8.2 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 KXS09939.1 - 0.0021 17.8 0.0 2.3 7.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 KXS09939.1 - 0.0024 18.1 0.4 6.7 6.9 0.0 3.3 2 1 0 2 2 2 0 AAA domain AAA_5 PF07728.14 KXS09939.1 - 0.0042 17.1 0.1 2.4 8.2 0.0 3.4 4 0 0 4 4 3 1 AAA domain (dynein-related subfamily) AAA PF00004.29 KXS09939.1 - 0.0046 17.4 7.4 3.2 8.2 0.2 4.5 3 2 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KXS09939.1 - 0.0048 17.4 0.0 1.8 9.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KXS09939.1 - 0.0054 17.1 0.0 2.1 8.8 0.0 3.1 3 0 0 3 3 3 1 RNA helicase APS_kinase PF01583.20 KXS09939.1 - 0.0071 16.2 0.0 0.82 9.5 0.0 2.6 2 0 0 2 2 2 1 Adenylylsulphate kinase NB-ARC PF00931.22 KXS09939.1 - 0.013 14.7 0.1 2.8 7.1 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain Rad17 PF03215.15 KXS09939.1 - 0.018 15.0 0.0 1.3 9.0 0.0 2.5 2 0 0 2 2 2 0 Rad17 P-loop domain DUF815 PF05673.13 KXS09939.1 - 0.03 13.5 0.0 0.34 10.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF815) PRK PF00485.18 KXS09939.1 - 0.031 14.0 0.0 4.9 6.8 0.0 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family DUF87 PF01935.17 KXS09939.1 - 0.037 14.1 2.6 0.74 9.9 0.0 2.9 3 0 0 3 3 3 0 Helicase HerA, central domain AAA_23 PF13476.6 KXS09939.1 - 0.042 14.4 5.3 5.5 7.4 0.0 3.3 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.6 KXS09939.1 - 0.064 12.8 2.7 8.3 5.9 0.4 3.1 2 1 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 KXS09939.1 - 0.076 12.8 1.3 23 4.7 0.0 3.6 4 0 0 4 4 4 0 IstB-like ATP binding protein MMR_HSR1 PF01926.23 KXS09939.1 - 0.1 12.7 0.2 14 5.8 0.1 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_17 PF13207.6 KXS09939.1 - 0.66 10.4 5.1 17 5.8 0.0 3.4 4 0 0 4 4 2 0 AAA domain CDC45 PF02724.14 KXS09939.1 - 2.4 6.3 6.0 3.8 5.7 6.0 1.2 1 0 0 1 1 1 0 CDC45-like protein ABC_tran PF00005.27 KXS09940.1 - 1.4e-13 51.5 0.0 1.8e-13 51.2 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_15 PF13175.6 KXS09940.1 - 0.0039 16.9 0.0 0.0042 16.9 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 KXS09940.1 - 0.055 13.3 0.0 0.085 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KXS09940.1 - 0.12 12.7 0.0 0.13 12.6 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 KXS09940.1 - 0.21 11.8 0.0 0.31 11.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain GST_N_2 PF13409.6 KXS09942.1 - 7.2e-26 90.3 0.4 7.8e-25 87.0 0.1 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KXS09942.1 - 5.4e-12 45.6 0.3 8.6e-10 38.5 0.0 2.9 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KXS09942.1 - 2e-05 24.9 0.8 0.0062 16.9 0.0 3.4 3 1 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KXS09942.1 - 0.13 12.5 0.0 0.37 11.0 0.0 1.9 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF1206 PF06724.11 KXS09943.1 - 7.2e-09 35.6 18.6 0.00046 20.2 0.2 3.7 3 1 1 4 4 4 4 Domain of Unknown Function (DUF1206) Pyridoxal_deC PF00282.19 KXS09944.1 - 4e-129 430.6 0.0 4.8e-129 430.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain MIF PF01187.18 KXS09945.1 - 5.6e-21 75.0 0.0 6.1e-21 74.8 0.0 1.0 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Tautomerase PF01361.21 KXS09945.1 - 6.2e-06 26.1 0.0 0.059 13.3 0.0 2.1 2 0 0 2 2 2 2 Tautomerase enzyme DUF1904 PF08921.11 KXS09945.1 - 0.07 13.4 0.0 0.081 13.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1904) Aminotran_3 PF00202.21 KXS09946.1 - 4.4e-95 318.7 0.0 5.4e-95 318.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 KXS09946.1 - 0.06 12.5 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class I and II Yip1 PF04893.17 KXS09947.1 - 2.4e-12 46.9 12.6 5.2e-12 45.8 12.6 1.6 1 0 0 1 1 1 1 Yip1 domain DDHD PF02862.17 KXS09948.1 - 7.5e-36 124.4 0.0 1.7e-32 113.4 0.0 3.9 3 1 0 3 3 3 1 DDHD domain Hydrolase_4 PF12146.8 KXS09948.1 - 0.027 13.8 0.2 0.1 11.8 0.0 2.0 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_9 PF10081.9 KXS09948.1 - 0.052 12.6 0.0 0.086 11.9 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta-hydrolase family DUF3915 PF13054.6 KXS09948.1 - 0.18 11.8 13.5 1.6 8.7 6.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) LIDHydrolase PF10230.9 KXS09948.1 - 0.27 10.7 0.0 0.45 10.0 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Vfa1 PF08432.10 KXS09948.1 - 1.1 9.6 10.1 4.1 7.7 3.9 2.2 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 bZIP_2 PF07716.15 KXS09949.1 - 7.1e-06 26.0 12.6 0.00022 21.2 2.0 3.5 4 0 0 4 4 3 2 Basic region leucine zipper ZapB PF06005.12 KXS09949.1 - 0.0026 18.2 8.3 0.0072 16.7 8.3 1.7 1 0 0 1 1 1 1 Cell division protein ZapB bZIP_1 PF00170.21 KXS09949.1 - 0.0089 16.1 4.0 0.0089 16.1 4.0 3.5 3 1 1 4 4 3 2 bZIP transcription factor DivIC PF04977.15 KXS09949.1 - 0.011 15.4 2.4 0.028 14.2 2.4 1.6 1 0 0 1 1 1 0 Septum formation initiator GAS PF13851.6 KXS09949.1 - 0.015 14.7 1.8 0.027 13.8 1.8 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Dzip-like_N PF13815.6 KXS09949.1 - 0.021 14.8 0.6 0.021 14.8 0.6 1.5 2 0 0 2 2 1 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal YscO-like PF16789.5 KXS09949.1 - 0.025 14.6 1.6 0.025 14.6 1.6 2.0 2 0 0 2 2 2 0 YscO-like protein UPF0564 PF10595.9 KXS09949.1 - 0.026 13.6 4.6 0.039 13.0 4.6 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0564 EzrA PF06160.12 KXS09949.1 - 0.057 11.6 0.3 0.071 11.3 0.3 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA DUF1664 PF07889.12 KXS09949.1 - 0.06 13.4 0.2 0.096 12.7 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF2203 PF09969.9 KXS09949.1 - 0.091 13.5 0.4 0.091 13.5 0.4 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Spc24 PF08286.11 KXS09949.1 - 0.25 11.6 1.6 0.54 10.5 1.6 1.6 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 UPF0242 PF06785.11 KXS09949.1 - 0.34 11.0 2.6 0.5 10.4 2.6 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus bZIP_Maf PF03131.17 KXS09949.1 - 1.2 9.7 14.1 4.1 8.0 5.4 2.3 2 0 0 2 2 2 0 bZIP Maf transcription factor XRCC4 PF06632.12 KXS09949.1 - 1.3 7.8 6.7 5.5 5.8 1.2 2.1 2 0 0 2 2 2 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Spc7 PF08317.11 KXS09949.1 - 1.4 7.8 7.7 3.2 6.6 7.7 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein Spc29 PF17082.5 KXS09949.1 - 1.4 8.7 7.9 3.2 7.5 7.9 1.5 1 1 0 1 1 1 0 Spindle Pole Component 29 KLRAQ PF10205.9 KXS09949.1 - 3.7 7.9 7.1 0.38 11.0 0.7 2.1 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein TMF_TATA_bd PF12325.8 KXS09949.1 - 10 6.4 11.0 0.25 11.6 4.0 1.8 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding zf-C2H2 PF00096.26 KXS09952.1 - 1.2e-09 38.1 3.0 4.2e-05 23.7 0.8 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXS09952.1 - 3.1e-07 30.6 3.6 0.009 16.8 0.7 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KXS09952.1 - 2.2e-06 27.8 0.3 2.2e-06 27.8 0.3 3.4 4 0 0 4 4 4 1 Zinc-finger double domain zf-met PF12874.7 KXS09952.1 - 0.0013 19.1 0.1 1.2 9.6 0.0 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 KXS09952.1 - 0.076 12.8 0.3 0.19 11.5 0.3 1.7 1 0 0 1 1 1 0 C2H2-type zinc-finger domain p450 PF00067.22 KXS09953.1 - 5.4e-77 259.5 0.0 7.3e-77 259.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 BAR PF03114.18 KXS09954.1 - 1.8e-41 142.4 0.1 2.2e-41 142.1 0.1 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 KXS09954.1 - 1.4e-13 50.2 0.1 2.5e-13 49.4 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KXS09954.1 - 3.6e-12 45.9 0.1 7.5e-12 44.9 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KXS09954.1 - 1.3e-07 31.1 0.1 2.5e-07 30.3 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain Arfaptin PF06456.13 KXS09954.1 - 0.026 14.1 0.5 0.61 9.6 0.0 2.3 2 0 0 2 2 2 0 Arfaptin-like domain HgmA PF04209.13 KXS09955.1 - 2.5e-142 474.5 0.0 3.2e-142 474.2 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase Proteasome PF00227.26 KXS09956.1 - 2.9e-53 180.2 0.3 4.1e-53 179.7 0.3 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KXS09956.1 - 6.3e-15 54.5 0.1 1.2e-14 53.6 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Pet191_N PF10203.9 KXS09957.1 - 4e-23 81.5 0.7 4.7e-23 81.3 0.7 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 CX9C PF16860.5 KXS09957.1 - 0.12 12.4 0.4 1.9 8.6 0.1 2.4 2 1 1 3 3 3 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, ADH_zinc_N PF00107.26 KXS09958.1 - 1.3e-15 57.6 0.5 2.1e-15 56.9 0.5 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXS09958.1 - 7.3e-08 33.5 0.0 3.2e-06 28.2 0.0 2.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXS09958.1 - 6.7e-06 26.0 0.0 2.4e-05 24.2 0.0 1.9 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Tctex-1 PF03645.13 KXS09959.1 - 3e-34 117.3 0.8 3.5e-34 117.1 0.8 1.1 1 0 0 1 1 1 1 Tctex-1 family GST_N PF02798.20 KXS09960.1 - 3.6e-11 43.3 0.0 6.8e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KXS09960.1 - 1.4e-10 41.5 0.0 2.5e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KXS09960.1 - 9.6e-10 38.6 0.0 1.6e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KXS09960.1 - 1.7e-09 37.8 0.0 2.8e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KXS09960.1 - 1.5e-06 28.3 0.0 2.7e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KXS09960.1 - 0.00046 20.2 0.0 0.00081 19.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Carb_anhydrase PF00194.21 KXS09961.1 - 3.5e-37 128.3 0.0 4.3e-37 128.0 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase F-box PF00646.33 KXS09962.1 - 0.0066 16.3 1.6 0.016 15.1 1.6 1.6 1 0 0 1 1 1 1 F-box domain EAL PF00563.20 KXS09962.1 - 0.025 14.1 0.0 0.047 13.2 0.0 1.6 1 0 0 1 1 1 0 EAL domain Carb_anhydrase PF00194.21 KXS09963.1 - 2.2e-37 129.0 0.0 2.8e-37 128.6 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Kelch_6 PF13964.6 KXS09964.1 - 1.3e-05 25.3 0.2 0.18 12.1 0.0 3.6 3 0 0 3 3 3 2 Kelch motif Kelch_5 PF13854.6 KXS09964.1 - 0.0029 17.5 0.1 0.24 11.4 0.0 2.8 2 0 0 2 2 2 1 Kelch motif Kelch_4 PF13418.6 KXS09964.1 - 0.016 15.2 0.2 6.3 6.9 0.0 3.3 3 0 0 3 3 3 0 Galactose oxidase, central domain Pkinase PF00069.25 KXS09967.1 - 8.6e-60 202.3 0.0 1e-58 198.8 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS09967.1 - 1.7e-25 89.8 0.6 4e-18 65.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 KXS09967.1 - 0.0016 17.5 0.1 0.0025 16.8 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KXS09967.1 - 0.0079 16.1 0.4 0.62 9.9 0.0 2.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KXS09967.1 - 0.008 15.6 0.0 0.018 14.4 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KXS09967.1 - 0.015 14.6 0.3 0.47 9.7 0.0 2.5 3 0 0 3 3 3 0 Kinase-like MtN3_slv PF03083.16 KXS09968.1 - 1.5e-29 101.8 9.6 3.9e-17 62.1 3.0 2.3 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange TMEM43 PF07787.12 KXS09968.1 - 3.5 6.9 6.4 10 5.4 6.3 1.8 1 1 0 1 1 1 0 Transmembrane protein 43 BB_PF PF18063.1 KXS09970.1 - 3.7e-47 160.6 2.6 4.7e-47 160.2 2.6 1.1 1 0 0 1 1 1 1 Beta barrel Pore-forming domain AMP-binding PF00501.28 KXS09972.1 - 1.6e-91 307.0 0.0 2e-91 306.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXS09972.1 - 6.2e-23 81.6 0.1 3.1e-22 79.3 0.4 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 KXS09972.1 - 7.3e-15 54.6 0.1 1.6e-14 53.5 0.1 1.6 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus Epimerase PF01370.21 KXS09973.1 - 3.1e-12 46.5 0.0 4.5e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KXS09973.1 - 4.3e-05 22.8 0.0 6.7e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 KXS09973.1 - 0.016 14.7 0.0 0.24 10.8 0.0 2.1 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase ASH PF15780.5 KXS09974.1 - 0.00054 20.1 1.1 0.41 10.9 0.0 4.1 3 1 0 3 3 3 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin S-antigen PF05756.11 KXS09974.1 - 2.3 8.6 3.5 7.5 7.0 3.5 1.8 1 0 0 1 1 1 0 S-antigen protein FAM184 PF15665.5 KXS09975.1 - 0.0002 21.2 29.2 0.0002 21.2 29.2 18.0 6 5 10 17 17 17 2 Family with sequence similarity 184, A and B MscS_porin PF12795.7 KXS09975.1 - 0.0021 17.6 11.1 0.0021 17.6 11.1 22.1 9 5 13 22 22 22 3 Mechanosensitive ion channel porin domain PEX11 PF05648.14 KXS09976.1 - 6e-20 71.7 0.0 6.9e-20 71.5 0.0 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Clathrin_H_link PF13838.6 KXS09976.1 - 0.071 13.0 0.5 6.6 6.7 0.1 2.5 2 0 0 2 2 2 0 Clathrin-H-link Synaptobrevin PF00957.21 KXS09979.1 - 7.1e-27 93.0 2.8 7.7e-27 92.9 2.8 1.0 1 0 0 1 1 1 1 Synaptobrevin Pex24p PF06398.11 KXS09979.1 - 0.027 13.5 0.0 0.027 13.4 0.0 1.0 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin ODV-E18 PF10717.9 KXS09979.1 - 0.042 13.7 1.1 0.049 13.5 1.1 1.2 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 CD34_antigen PF06365.12 KXS09979.1 - 0.12 12.0 0.7 0.13 11.9 0.7 1.0 1 0 0 1 1 1 0 CD34/Podocalyxin family UPF0258 PF06789.12 KXS09979.1 - 0.13 12.3 0.9 0.13 12.4 0.9 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0258) DUF2116 PF09889.9 KXS09979.1 - 0.8 9.7 3.3 1.1 9.3 3.3 1.4 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) CPSase_L_D2 PF02786.17 KXS09980.1 - 1.6e-64 217.3 0.1 2.9e-64 216.4 0.1 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 KXS09980.1 - 1.9e-35 121.7 0.0 3e-34 117.9 0.0 2.3 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KXS09980.1 - 4.2e-26 91.2 0.0 2.4e-25 88.7 0.0 2.3 1 1 0 1 1 1 1 Biotin carboxylase C-terminal domain Dala_Dala_lig_C PF07478.13 KXS09980.1 - 8.6e-11 41.7 0.0 2e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl PF00364.22 KXS09980.1 - 2e-10 40.3 2.8 3.2e-09 36.5 0.4 2.5 1 1 1 2 2 2 1 Biotin-requiring enzyme ATP-grasp_3 PF02655.14 KXS09980.1 - 4.7e-07 30.0 0.1 8.9e-07 29.1 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.22 KXS09980.1 - 4.8e-07 29.5 0.1 9.7e-07 28.5 0.1 1.4 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 KXS09980.1 - 0.00067 19.4 0.1 0.0022 17.8 0.1 2.0 1 0 0 1 1 1 1 Biotin-lipoyl like ATPgrasp_ST PF14397.6 KXS09980.1 - 0.00094 18.5 0.0 0.0032 16.8 0.0 1.8 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp HlyD_3 PF13437.6 KXS09980.1 - 0.0012 19.5 0.6 0.03 15.0 0.1 2.8 1 1 1 2 2 2 1 HlyD family secretion protein RnfC_N PF13375.6 KXS09980.1 - 0.021 14.8 0.1 0.087 12.8 0.1 2.1 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain ATPgrasp_Ter PF15632.6 KXS09980.1 - 0.038 13.7 0.1 0.15 11.8 0.0 2.0 2 0 0 2 2 2 0 ATP-grasp in the biosynthetic pathway with Ter operon GCV_H PF01597.19 KXS09980.1 - 0.46 10.4 2.2 6.2 6.7 0.1 2.7 3 0 0 3 3 3 0 Glycine cleavage H-protein DUF2236 PF09995.9 KXS09981.1 - 1.5e-09 38.4 0.4 2.3e-09 37.8 0.4 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) DM13 PF10517.9 KXS09983.1 - 3.8e-12 46.7 0.1 1.1e-11 45.3 0.0 1.7 2 0 0 2 2 2 1 Electron transfer DM13 DOMON PF03351.17 KXS09983.1 - 6.1e-09 36.2 1.2 1.5e-08 34.9 0.1 2.3 2 1 0 2 2 2 1 DOMON domain NIR_SIR PF01077.22 KXS09983.1 - 0.17 11.4 0.0 0.44 10.0 0.0 1.8 1 1 0 1 1 1 0 Nitrite and sulphite reductase 4Fe-4S domain DEC-1_N PF04625.13 KXS09983.1 - 3.7 6.5 6.0 6.1 5.7 6.0 1.3 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region DUF2263 PF10021.9 KXS09984.1 - 1.6e-23 83.7 0.0 2.4e-23 83.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Phage_holin_3_6 PF07332.11 KXS09985.1 - 3 7.9 12.1 4.6 7.3 12.1 1.2 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Spem1 PF15670.5 KXS09987.1 - 0.19 11.3 9.3 0.21 11.2 9.3 1.2 1 0 0 1 1 1 0 Spermatid maturation protein 1 VIR_N PF15912.5 KXS09987.1 - 0.94 9.0 10.2 1.3 8.5 10.2 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal Aquarius_N PF16399.5 KXS09989.1 - 9.4e-124 414.2 0.0 7e-117 391.5 0.0 2.1 2 0 0 2 2 2 2 Intron-binding protein aquarius N-terminus AAA_11 PF13086.6 KXS09989.1 - 2.6e-29 102.8 0.0 1.2e-28 100.6 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_12 PF13087.6 KXS09989.1 - 4.2e-26 91.8 0.0 1.6e-25 89.9 0.0 2.1 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.6 KXS09989.1 - 6.7e-09 36.2 0.0 9.4e-08 32.5 0.0 2.7 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KXS09989.1 - 9.1e-06 25.5 0.0 0.016 14.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain ResIII PF04851.15 KXS09989.1 - 0.00029 20.9 0.0 0.00059 19.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 KXS09989.1 - 0.00076 19.1 0.0 0.0015 18.2 0.0 1.4 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA PF00004.29 KXS09989.1 - 0.0023 18.3 0.0 0.0054 17.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) UvrD_C_2 PF13538.6 KXS09989.1 - 0.014 15.2 0.1 0.035 13.9 0.1 1.7 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA_25 PF13481.6 KXS09989.1 - 0.019 14.6 0.0 0.06 12.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 KXS09989.1 - 0.026 13.8 0.1 0.54 9.4 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.6 KXS09989.1 - 0.031 14.7 0.0 0.14 12.6 0.0 2.1 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 KXS09989.1 - 0.037 14.3 0.0 0.28 11.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 KXS09989.1 - 0.075 12.5 0.1 0.47 9.9 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein DnaB_C PF03796.15 KXS09989.1 - 0.11 11.8 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_23 PF13476.6 KXS09989.1 - 0.13 12.7 0.0 0.3 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain F-box-like PF12937.7 KXS09990.1 - 0.075 12.9 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 F-box-like Tubulin PF00091.25 KXS09991.1 - 3e-64 216.9 0.0 4e-64 216.4 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KXS09991.1 - 2.7e-45 153.6 0.0 4.5e-45 152.9 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KXS09991.1 - 0.00034 20.4 0.0 0.00086 19.0 0.0 1.6 2 0 0 2 2 2 1 Tubulin domain adh_short_C2 PF13561.6 KXS09992.1 - 2.6e-46 158.1 0.0 3.1e-46 157.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXS09992.1 - 2.2e-39 135.0 0.0 2.8e-39 134.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXS09992.1 - 0.00015 21.7 0.0 0.00022 21.2 0.0 1.4 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KXS09992.1 - 0.081 12.3 0.1 0.14 11.5 0.1 1.3 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) DUF2034 PF10356.9 KXS09993.1 - 5.8e-15 55.2 0.0 2.5e-07 30.3 0.0 2.5 1 1 1 2 2 2 2 Protein of unknown function (DUF2034) Mrr_cat PF04471.12 KXS09993.1 - 1.5e-08 34.6 0.0 8.1e-08 32.3 0.0 1.9 1 1 0 1 1 1 1 Restriction endonuclease Collagen PF01391.18 KXS09993.1 - 4.1 7.2 13.6 0.57 10.0 8.4 1.9 2 0 0 2 2 2 0 Collagen triple helix repeat (20 copies) MutS_V PF00488.21 KXS09994.1 - 1.1e-65 221.2 0.0 1.8e-65 220.5 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KXS09994.1 - 2.7e-08 34.3 0.0 5e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 MutS domain III AAA_29 PF13555.6 KXS09994.1 - 0.044 13.5 0.1 0.094 12.5 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF5315 PF17242.2 KXS09994.1 - 0.071 12.9 0.2 0.86 9.5 0.0 2.4 2 0 0 2 2 2 0 Disordered region of unknown function (DUF5315) Pyrophosphatase PF00719.19 KXS09994.1 - 0.11 12.3 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Inorganic pyrophosphatase RuBisCO_large PF00016.20 KXS09995.1 - 0.00013 21.3 14.6 10 5.2 0.1 7.4 1 1 7 8 8 8 5 Ribulose bisphosphate carboxylase large chain, catalytic domain Hpr_kinase_N PF02603.16 KXS09995.1 - 0.013 15.5 0.0 46 4.1 0.0 4.3 1 1 3 5 5 5 0 HPr Serine kinase N terminus Gp45_2 PF17470.2 KXS09995.1 - 0.019 14.9 2.6 59 3.7 0.0 5.0 6 0 0 6 6 6 0 Phage gene product 45.2 eIF3_N PF09440.10 KXS09995.1 - 2.5 8.6 9.6 0.46 10.9 0.5 3.6 1 1 5 6 6 6 0 eIF3 subunit 6 N terminal domain RRM_1 PF00076.22 KXS09996.1 - 1.2e-15 57.0 0.0 1.9e-15 56.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KXS09996.1 - 0.017 15.2 0.1 0.028 14.4 0.1 1.4 1 0 0 1 1 1 0 RNA binding motif RL PF17797.1 KXS09996.1 - 0.1 12.6 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 RL domain Ank_5 PF13857.6 KXS10000.1 - 1.3e-06 28.5 0.0 3.8e-06 27.1 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXS10000.1 - 0.00016 22.2 0.0 0.00033 21.2 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXS10000.1 - 0.0003 21.3 0.1 0.0046 17.5 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXS10000.1 - 0.00068 19.9 0.4 0.0078 16.6 0.0 2.9 4 0 0 4 4 4 1 Ankyrin repeat Ank PF00023.30 KXS10000.1 - 0.0097 16.3 0.0 0.038 14.4 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeat HAT_KAT11 PF08214.11 KXS10001.1 - 1.3e-20 74.0 0.0 3.4e-20 72.6 0.0 1.6 1 1 0 1 1 1 1 Histone acetylation protein Acyl-CoA_dh_1 PF00441.24 KXS10002.1 - 6.4e-41 140.0 0.8 1e-40 139.4 0.8 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KXS10002.1 - 4.3e-21 74.9 0.0 7.6e-21 74.1 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KXS10002.1 - 6.7e-13 49.3 0.0 5.7e-12 46.3 0.0 2.5 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KXS10002.1 - 4.6e-10 39.9 0.2 7.6e-10 39.2 0.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 KXS10002.1 - 9.4e-05 22.2 0.0 0.00019 21.2 0.0 1.5 1 0 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal Ank_3 PF13606.6 KXS10004.1 - 1.1e-06 28.5 0.0 0.001 19.3 0.0 3.5 3 0 0 3 3 3 1 Ankyrin repeat SH3_9 PF14604.6 KXS10004.1 - 4e-06 26.6 0.2 6.5e-06 25.9 0.2 1.4 1 0 0 1 1 1 1 Variant SH3 domain Ank PF00023.30 KXS10004.1 - 0.00014 22.1 0.2 0.075 13.5 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeat SH3_1 PF00018.28 KXS10004.1 - 0.00083 18.9 0.0 0.0014 18.2 0.0 1.4 1 0 0 1 1 1 1 SH3 domain Ank_2 PF12796.7 KXS10004.1 - 0.0015 19.1 0.0 0.011 16.3 0.0 2.3 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXS10004.1 - 0.006 16.9 0.0 0.029 14.7 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXS10004.1 - 0.06 13.9 0.0 0.21 12.2 0.0 2.0 2 0 0 2 2 2 0 Ankyrin repeats (many copies) dCache_2 PF08269.11 KXS10004.1 - 0.074 12.2 2.3 0.1 11.7 2.3 1.1 1 0 0 1 1 1 0 Cache domain CdvA PF18822.1 KXS10004.1 - 0.1 12.4 5.0 0.14 12.0 4.3 1.6 1 1 1 2 2 2 0 CdvA-like coiled-coil domain MRP-S31 PF15433.6 KXS10004.1 - 0.17 11.6 1.8 0.23 11.1 1.8 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 zf-MYND PF01753.18 KXS10005.1 - 3.3e-08 33.5 8.2 3.3e-08 33.5 8.2 2.0 2 0 0 2 2 2 1 MYND finger RPAP2_Rtr1 PF04181.13 KXS10005.1 - 0.34 11.3 3.4 0.87 10.0 3.4 1.6 1 0 0 1 1 1 0 Rtr1/RPAP2 family zf-C6H2 PF15801.5 KXS10005.1 - 6.3 7.2 8.4 0.83 10.0 3.6 2.0 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding YIF1 PF03878.15 KXS10006.1 - 8.2e-76 254.7 1.6 1.1e-75 254.3 1.6 1.1 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.17 KXS10006.1 - 2.1e-05 24.3 10.0 2.1e-05 24.3 10.0 1.5 1 1 0 1 1 1 1 Yip1 domain Wzy_C PF04932.15 KXS10006.1 - 0.91 9.1 8.0 0.23 11.1 4.3 1.9 1 1 1 2 2 2 0 O-Antigen ligase HAUS6_N PF14661.6 KXS10007.1 - 1.4e-18 67.3 0.0 1.1e-11 44.8 0.0 2.1 1 1 1 2 2 2 2 HAUS augmin-like complex subunit 6 N-terminus Thymosin PF01290.20 KXS10009.1 - 7e-12 44.9 0.8 7.9e-12 44.7 0.8 1.1 1 0 0 1 1 1 1 Thymosin beta-4 family DUF4522 PF15022.6 KXS10009.1 - 0.029 14.7 0.0 0.029 14.6 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4522) GTP_EFTU PF00009.27 KXS10010.1 - 2.2e-49 167.6 0.0 3.4e-49 167.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 KXS10010.1 - 1.2e-44 150.8 5.3 2.3e-44 149.9 5.3 1.4 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 KXS10010.1 - 4.1e-20 71.6 0.0 9.3e-20 70.5 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus RF3_C PF16658.5 KXS10010.1 - 4.3e-07 29.8 0.0 8.4e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain GTP_EFTU_D2 PF03144.25 KXS10010.1 - 1.5e-06 28.5 0.4 3e-06 27.5 0.1 1.8 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.6 KXS10010.1 - 1e-05 25.5 0.0 2.5e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 KXS10010.1 - 0.00015 21.8 0.0 0.00034 20.7 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 KXS10010.1 - 0.0038 16.9 0.0 0.0066 16.1 0.0 1.3 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 KXS10010.1 - 0.054 12.9 0.0 0.16 11.4 0.0 1.8 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF2745 PF10922.8 KXS10010.1 - 0.087 13.1 0.0 2.2 8.6 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2745) CS PF04969.16 KXS10011.1 - 9.1e-05 23.4 1.2 9.7e-05 23.3 0.3 1.5 2 0 0 2 2 2 1 CS domain PRKCSH PF07915.13 KXS10012.1 - 6.7e-13 49.5 1.3 1.4e-12 48.4 0.2 2.1 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein Ribosomal_L6e PF01159.19 KXS10013.1 - 5.7e-33 113.8 0.2 1.7e-32 112.2 0.2 1.8 1 1 0 1 1 1 1 Ribosomal protein L6e Ribosomal_L6e_N PF03868.15 KXS10013.1 - 0.0015 18.7 1.8 0.0016 18.7 0.2 1.9 2 0 0 2 2 2 1 Ribosomal protein L6, N-terminal domain Pkinase PF00069.25 KXS10014.1 - 1.8e-71 240.6 0.0 2.3e-71 240.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS10014.1 - 2.7e-27 95.7 0.0 3.6e-27 95.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXS10014.1 - 3.6e-06 26.5 0.0 1.1e-05 24.9 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KXS10014.1 - 0.00022 21.2 0.0 0.00055 19.9 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KXS10014.1 - 0.0036 16.7 0.0 0.0063 15.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 KXS10014.1 - 0.087 12.3 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Pkinase PF00069.25 KXS10015.1 - 4.1e-70 236.2 0.0 5.3e-70 235.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS10015.1 - 1.7e-28 99.6 0.0 2.4e-28 99.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXS10015.1 - 1.6e-05 24.4 0.0 5.3e-05 22.7 0.0 1.7 1 1 1 2 2 2 1 Kinase-like APH PF01636.23 KXS10015.1 - 0.00013 22.0 0.0 0.00027 21.0 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KXS10015.1 - 0.00016 21.1 0.0 0.00029 20.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 KXS10015.1 - 0.099 12.1 0.3 3.5 7.1 0.0 2.2 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Pkinase_fungal PF17667.1 KXS10015.1 - 0.17 10.6 0.1 0.43 9.3 0.0 1.6 2 0 0 2 2 2 0 Fungal protein kinase ORC6 PF05460.13 KXS10015.1 - 3.1 7.0 6.8 2.1 7.6 1.4 2.2 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) eIF3_N PF09440.10 KXS10016.1 - 1.7e-43 148.2 3.2 2.7e-43 147.6 1.9 2.0 2 0 0 2 2 2 1 eIF3 subunit 6 N terminal domain PCI PF01399.27 KXS10016.1 - 2.7e-14 53.6 0.0 1.4e-13 51.3 0.0 2.2 2 0 0 2 2 2 1 PCI domain CelTOS PF18659.1 KXS10016.1 - 0.085 13.3 0.1 0.26 11.7 0.1 1.8 1 0 0 1 1 1 0 Cell-traversal protein for ookinetes and sporozoites NUDIX PF00293.28 KXS10017.1 - 2.7e-13 50.1 0.1 1.2e-11 44.8 0.0 2.1 2 0 0 2 2 2 2 NUDIX domain DUF4806 PF16064.5 KXS10017.1 - 0.13 12.6 0.0 0.25 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4806) Kinesin PF00225.23 KXS10018.1 - 8.3e-119 396.4 0.0 9.4e-119 396.2 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KXS10018.1 - 1e-26 93.7 0.0 1.8e-26 92.9 0.0 1.3 1 0 0 1 1 1 1 Microtubule binding AAA_22 PF13401.6 KXS10018.1 - 0.0035 17.6 0.0 0.013 15.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain PIF1 PF05970.14 KXS10018.1 - 0.031 13.4 0.0 0.068 12.3 0.0 1.5 1 0 0 1 1 1 0 PIF1-like helicase AAA_30 PF13604.6 KXS10018.1 - 0.034 13.9 0.0 0.07 12.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain Bac_rhamnosid6H PF17389.2 KXS10019.1 - 4.9e-11 42.5 0.0 3.2e-10 39.8 0.0 1.9 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_C PF17390.2 KXS10019.1 - 4.3e-06 26.4 0.0 1.4e-05 24.8 0.0 1.9 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase C-terminal domain NP1-WLL PF11733.8 KXS10019.1 - 0.07 12.9 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Non-capsid protein NP1 Glyco_hydro_36 PF17167.4 KXS10019.1 - 0.077 11.7 0.0 0.12 11.0 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase 36 superfamily, catalytic domain 4HBT_3 PF13622.6 KXS10020.1 - 6.5e-09 36.4 0.3 9.1e-09 35.9 0.3 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily DUF2678 PF10856.8 KXS10022.1 - 7.9e-15 54.8 0.8 1e-14 54.4 0.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2678) COX6A PF02046.15 KXS10023.1 - 3.3e-10 40.4 0.6 3.7e-10 40.3 0.6 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa Pro_isomerase PF00160.21 KXS10024.1 - 1.6e-43 148.7 0.2 2.5e-43 148.1 0.2 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 KXS10024.1 - 1e-18 66.9 0.0 1.7e-18 66.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KXS10024.1 - 0.02 15.0 0.0 0.04 14.0 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif COG4 PF08318.12 KXS10025.1 - 5.2e-66 223.0 0.0 8.3e-66 222.3 0.0 1.3 1 0 0 1 1 1 1 COG4 transport protein RINT1_TIP1 PF04437.13 KXS10025.1 - 6.4e-07 28.6 0.7 1.2e-06 27.8 0.7 1.4 1 0 0 1 1 1 1 RINT-1 / TIP-1 family Sec10 PF07393.11 KXS10025.1 - 0.0019 16.7 1.1 0.0019 16.7 1.1 1.6 2 0 0 2 2 2 1 Exocyst complex component Sec10 MEIOC PF15189.6 KXS10025.1 - 0.17 11.5 1.9 0.33 10.5 0.7 2.0 2 0 0 2 2 2 0 Meiosis-specific coiled-coil domain-containing protein MEIOC TPR_19 PF14559.6 KXS10025.1 - 0.29 11.7 1.7 45 4.7 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Glyco_transf_49 PF13896.6 KXS10026.1 - 9.4e-47 160.0 0.1 8.6e-44 150.2 0.1 2.8 1 1 0 1 1 1 1 Glycosyl-transferase for dystroglycan CECR6_TMEM121 PF14997.6 KXS10026.1 - 0.15 11.9 0.0 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 CECR6/TMEM121 family FA_desaturase PF00487.24 KXS10027.1 - 1.6e-29 103.5 25.4 2.2e-29 103.0 25.4 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 KXS10027.1 - 5.5e-14 52.1 0.0 1e-13 51.2 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain TMEM208_SND2 PF05620.11 KXS10027.1 - 2.2 8.1 4.1 8.9 6.1 0.6 2.3 2 0 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 Iso_dh PF00180.20 KXS10028.1 - 2.6e-97 326.1 0.0 1.8e-96 323.4 0.0 1.8 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Oxidored_molyb PF00174.19 KXS10029.1 - 1.6e-48 164.5 0.0 3.4e-48 163.5 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 KXS10029.1 - 2e-29 102.4 0.1 4.6e-29 101.2 0.1 1.6 1 1 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Cyt-b5 PF00173.28 KXS10029.1 - 6.6e-13 48.6 0.0 1.3e-12 47.6 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Big_7 PF17957.1 KXS10029.1 - 0.015 16.1 0.0 0.04 14.7 0.0 1.8 1 0 0 1 1 1 0 Bacterial Ig domain Aconitase PF00330.20 KXS10030.1 - 4.4e-106 355.6 0.1 4.6e-105 352.3 0.1 2.0 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KXS10030.1 - 2.7e-22 79.5 0.0 5.3e-22 78.6 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Aminotran_3 PF00202.21 KXS10031.1 - 7.5e-92 308.1 0.0 9e-92 307.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III NMD3 PF04981.13 KXS10032.1 - 1.7e-80 270.0 1.7 2.2e-80 269.7 1.7 1.1 1 0 0 1 1 1 1 NMD3 family Chromo PF00385.24 KXS10034.1 - 0.00018 21.3 7.0 0.093 12.7 0.3 3.0 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain HEAT PF02985.22 KXS10035.1 - 2.8e-07 30.2 19.2 0.074 13.3 0.0 8.3 8 0 0 8 8 8 4 HEAT repeat HEAT_2 PF13646.6 KXS10035.1 - 1.3e-06 28.7 11.6 0.59 10.6 0.0 7.1 6 2 1 7 7 7 3 HEAT repeats Arm PF00514.23 KXS10035.1 - 0.012 15.6 0.3 0.012 15.6 0.3 6.6 9 0 0 9 9 9 0 Armadillo/beta-catenin-like repeat Zincin_2 PF10103.9 KXS10035.1 - 0.58 9.4 4.8 0.075 12.3 0.2 1.8 2 0 0 2 2 2 0 Zincin-like metallopeptidase Voltage_CLC PF00654.20 KXS10036.1 - 1.6e-79 267.7 24.4 1.6e-79 267.7 24.4 2.1 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 KXS10036.1 - 4.3e-11 43.1 0.2 4.5e-05 23.8 0.0 2.5 2 0 0 2 2 2 2 CBS domain PDZ_5 PF17817.1 KXS10040.1 - 0.05 13.9 0.1 0.092 13.0 0.1 1.4 1 0 0 1 1 1 0 PDZ domain Nodulin PF02451.15 KXS10041.1 - 0.038 13.5 1.5 0.061 12.8 1.5 1.2 1 0 0 1 1 1 0 Nodulin LIM PF00412.22 KXS10042.1 - 1.6e-13 50.6 4.3 2.1e-13 50.3 4.3 1.1 1 0 0 1 1 1 1 LIM domain OrfB_Zn_ribbon PF07282.11 KXS10042.1 - 0.032 14.1 0.8 0.07 13.1 0.8 1.6 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-RRN7 PF11781.8 KXS10042.1 - 0.05 13.3 4.7 0.32 10.7 1.0 2.5 2 1 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zf-TFIIB PF13453.6 KXS10042.1 - 0.051 12.9 3.8 0.14 11.5 3.8 1.7 1 1 0 1 1 1 0 Transcription factor zinc-finger zf-ACC PF17848.1 KXS10042.1 - 0.051 13.6 2.8 0.9 9.7 0.5 2.3 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain Zn_Tnp_IS1595 PF12760.7 KXS10042.1 - 2.6 8.1 8.5 5 7.2 7.0 2.0 1 1 1 2 2 2 0 Transposase zinc-ribbon domain Methyltransf_34 PF11312.8 KXS10043.1 - 8.3e-47 159.9 0.0 1.5e-46 159.0 0.0 1.4 1 1 0 1 1 1 1 Putative SAM-dependent methyltransferase DUF4629 PF15442.6 KXS10043.1 - 0.079 13.2 0.3 0.14 12.4 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4629) GNAT_acetyltr_2 PF13718.6 KXS10044.1 - 7.3e-77 257.8 0.0 1.3e-76 257.0 0.0 1.4 1 0 0 1 1 1 1 GNAT acetyltransferase 2 tRNA_bind_2 PF13725.6 KXS10044.1 - 1.8e-60 204.6 0.0 1.4e-49 168.9 0.0 2.5 1 1 1 2 2 2 2 Possible tRNA binding domain Helicase_RecD PF05127.14 KXS10044.1 - 1.2e-56 191.3 0.0 3e-56 190.1 0.0 1.7 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.11 KXS10044.1 - 1.4e-32 111.5 0.0 4.7e-32 109.8 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1726) AAA_22 PF13401.6 KXS10044.1 - 0.0052 17.1 0.1 0.38 11.0 0.0 2.6 1 1 1 2 2 2 1 AAA domain Acetyltransf_7 PF13508.7 KXS10044.1 - 0.033 14.6 0.2 0.61 10.6 0.1 2.8 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXS10044.1 - 0.045 14.0 0.0 0.36 11.1 0.0 2.5 3 0 0 3 3 3 0 Acetyltransferase (GNAT) family DDE_Tnp_4 PF13359.6 KXS10045.1 - 3e-09 36.7 0.0 3.9e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 KXS10045.1 - 0.022 14.4 0.0 0.027 14.1 0.0 1.1 1 0 0 1 1 1 0 Transposase DDE domain N6_N4_Mtase PF01555.18 KXS10048.1 - 0.052 13.3 0.0 0.095 12.4 0.0 1.5 1 1 0 1 1 1 0 DNA methylase Cwf_Cwc_15 PF04889.12 KXS10049.1 - 0.24 11.1 5.0 0.25 11.1 5.0 1.0 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DNA_pol_phi PF04931.13 KXS10049.1 - 0.74 7.8 4.0 0.74 7.8 4.0 1.0 1 0 0 1 1 1 0 DNA polymerase phi MFS_1 PF07690.16 KXS10050.1 - 6e-27 94.5 39.3 6e-27 94.5 39.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ABC_tran PF00005.27 KXS10051.1 - 1.1e-43 149.1 1.1 1.6e-23 83.7 0.0 3.9 3 1 0 3 3 2 2 ABC transporter AAA_21 PF13304.6 KXS10051.1 - 4.4e-14 53.0 11.1 0.0074 16.1 0.2 4.3 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran_Xtn PF12848.7 KXS10051.1 - 5.3e-10 39.2 6.5 5.3e-10 39.2 6.5 2.8 3 0 0 3 3 3 1 ABC transporter SMC_N PF02463.19 KXS10051.1 - 6.6e-07 29.0 0.9 0.67 9.3 0.0 4.1 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KXS10051.1 - 8.3e-07 29.1 0.5 0.0065 16.5 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 KXS10051.1 - 1e-06 28.4 2.4 0.056 13.2 0.2 3.4 3 0 0 3 3 3 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KXS10051.1 - 3.2e-06 27.2 0.3 0.065 13.1 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 KXS10051.1 - 0.0017 18.7 0.1 4.3 7.6 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_18 PF13238.6 KXS10051.1 - 0.0056 17.2 0.6 1.5 9.4 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA PF00004.29 KXS10051.1 - 0.007 16.8 0.1 2.1 8.8 0.1 3.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) MeaB PF03308.16 KXS10051.1 - 0.015 14.3 2.8 0.5 9.3 0.3 2.9 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_33 PF13671.6 KXS10051.1 - 0.016 15.3 0.9 0.92 9.7 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.6 KXS10051.1 - 0.018 15.5 8.5 0.98 9.8 0.0 3.9 3 1 0 3 3 2 0 AAA ATPase domain NACHT PF05729.12 KXS10051.1 - 0.02 14.8 2.5 5.3 6.9 0.1 3.3 4 0 0 4 4 3 0 NACHT domain DUF87 PF01935.17 KXS10051.1 - 0.023 14.8 8.6 1 9.4 0.4 3.7 3 0 0 3 3 3 0 Helicase HerA, central domain AAA_14 PF13173.6 KXS10051.1 - 0.028 14.5 0.0 4.8 7.2 0.0 3.0 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 KXS10051.1 - 0.04 13.8 0.8 2.6 7.9 0.1 2.7 2 0 0 2 2 2 0 NTPase RNA_helicase PF00910.22 KXS10051.1 - 0.04 14.3 0.1 3.8 7.9 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_28 PF13521.6 KXS10051.1 - 0.057 13.7 2.7 2.5 8.3 0.0 3.4 3 1 0 3 3 3 0 AAA domain AAA_23 PF13476.6 KXS10051.1 - 0.062 13.8 0.2 0.062 13.8 0.2 4.3 4 1 0 4 4 3 0 AAA domain DUF2572 PF10833.8 KXS10051.1 - 0.074 12.8 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2572) Roc PF08477.13 KXS10051.1 - 0.098 12.9 1.2 26 5.0 0.0 3.2 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase EIIA-man PF03610.16 KXS10051.1 - 0.13 12.6 0.3 0.83 9.9 0.0 2.5 3 0 0 3 3 3 0 PTS system fructose IIA component AAA_24 PF13479.6 KXS10051.1 - 0.15 11.8 3.2 3.9 7.1 0.1 3.3 4 0 0 4 4 4 0 AAA domain Dynamin_N PF00350.23 KXS10051.1 - 0.25 11.4 3.9 0.36 10.9 0.0 3.2 5 0 0 5 5 5 0 Dynamin family AAA_15 PF13175.6 KXS10051.1 - 4.9 6.8 12.7 1.3 8.7 0.0 3.7 4 1 1 5 5 5 0 AAA ATPase domain IQ PF00612.27 KXS10052.1 - 0.016 15.0 0.2 0.043 13.6 0.2 1.8 1 0 0 1 1 1 0 IQ calmodulin-binding motif HAD_2 PF13419.6 KXS10053.1 - 2.7e-09 37.4 0.0 6.2e-09 36.2 0.0 1.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KXS10053.1 - 2.7e-08 34.4 0.0 9.2e-08 32.6 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KXS10053.1 - 3.6e-07 30.1 0.0 7.5e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 KXS10053.1 - 0.095 12.8 0.0 0.37 10.9 0.0 1.9 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase ECH_1 PF00378.20 KXS10054.1 - 2.4e-42 145.0 0.0 3.9e-42 144.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXS10054.1 - 1.3e-16 61.0 0.0 1.2e-15 57.8 0.0 1.9 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase GST_N_2 PF13409.6 KXS10055.1 - 1.1e-11 44.8 0.0 4.9e-11 42.8 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KXS10055.1 - 5.1e-10 39.6 0.0 8.7e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KXS10055.1 - 2.6e-09 37.3 0.0 5.3e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KXS10055.1 - 4.8e-06 26.7 0.0 1.1e-05 25.6 0.0 1.5 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KXS10055.1 - 0.00014 22.0 0.0 0.00024 21.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KXS10055.1 - 0.016 15.2 0.0 0.069 13.2 0.0 1.9 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Nsp1_C PF05064.13 KXS10056.1 - 7.8e-19 67.6 1.2 1.7e-18 66.5 1.2 1.4 1 0 0 1 1 1 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.6 KXS10056.1 - 2.9e-11 44.0 55.1 3.1e-07 31.1 19.0 9.8 2 1 9 11 11 11 3 Nucleoporin FG repeat region Tropomyosin PF00261.20 KXS10056.1 - 0.0039 16.6 4.3 0.083 12.3 0.5 2.1 2 0 0 2 2 2 2 Tropomyosin APG6_N PF17675.1 KXS10056.1 - 0.026 15.0 5.1 0.2 12.2 0.5 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region FliJ PF02050.16 KXS10056.1 - 0.046 14.0 7.1 0.91 9.8 0.6 2.2 2 0 0 2 2 2 0 Flagellar FliJ protein CENP-K PF11802.8 KXS10056.1 - 0.088 12.4 0.2 0.14 11.7 0.2 1.2 1 0 0 1 1 1 0 Centromere-associated protein K DHR10 PF18595.1 KXS10056.1 - 0.39 10.8 5.7 6.6 6.8 0.9 2.2 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain KfrA_N PF11740.8 KXS10056.1 - 3.2 8.5 11.6 2.6 8.7 3.8 2.7 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term TMEM219 PF14940.6 KXS10057.1 - 0.078 12.5 0.0 0.091 12.3 0.0 1.1 1 0 0 1 1 1 0 Transmembrane 219 RGS PF00615.19 KXS10058.1 - 0.00054 20.2 0.0 0.00073 19.8 0.0 1.1 1 0 0 1 1 1 1 Regulator of G protein signaling domain SH3_9 PF14604.6 KXS10059.1 - 3.1e-07 30.2 0.0 7.1e-07 29.0 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXS10059.1 - 6.6e-05 22.4 0.0 0.00015 21.3 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KXS10059.1 - 0.00013 21.5 0.0 0.00029 20.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Ank_2 PF12796.7 KXS10059.1 - 0.0034 18.0 0.0 0.019 15.6 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXS10059.1 - 0.0072 16.8 0.0 0.11 13.1 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 KXS10059.1 - 0.027 14.8 0.0 0.13 12.6 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank PF00023.30 KXS10059.1 - 0.073 13.6 0.0 0.56 10.8 0.0 2.5 2 0 0 2 2 2 0 Ankyrin repeat MAD PF05557.13 KXS10059.1 - 1.5 7.1 42.9 1.9 6.7 6.7 3.6 2 1 0 2 2 2 0 Mitotic checkpoint protein DUF4407 PF14362.6 KXS10059.1 - 1.7 7.9 41.4 0.051 12.9 5.5 3.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) Transketolase_N PF00456.21 KXS10060.1 - 1.6e-145 484.3 0.1 2e-145 483.9 0.1 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 KXS10060.1 - 5.3e-40 137.0 0.0 1.7e-39 135.3 0.0 1.9 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KXS10060.1 - 6.4e-11 42.2 0.0 1.5e-10 41.0 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 KXS10060.1 - 0.00019 20.8 0.1 0.00028 20.2 0.1 1.2 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 KXS10060.1 - 0.0025 17.6 2.2 0.022 14.5 0.6 3.2 1 1 1 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Abhydrolase_1 PF00561.20 KXS10061.1 - 8.2e-11 42.0 0.0 2.7e-10 40.3 0.1 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXS10061.1 - 0.0021 18.7 0.2 0.0032 18.1 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family UPF0014 PF03649.13 KXS10062.1 - 1.6e-64 217.6 25.5 1.8e-64 217.4 25.5 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0014) FtsX PF02687.21 KXS10062.1 - 0.011 16.2 3.0 0.011 16.2 3.0 3.4 2 1 1 3 3 3 0 FtsX-like permease family SH3_9 PF14604.6 KXS10063.1 - 2e-17 62.8 0.2 1.8e-08 34.1 0.0 2.8 3 0 0 3 3 3 2 Variant SH3 domain zf-C3HC4_3 PF13920.6 KXS10063.1 - 2.5e-17 62.5 8.8 3.7e-17 61.9 8.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) SH3_1 PF00018.28 KXS10063.1 - 1.8e-15 56.2 0.0 3.2e-07 29.9 0.0 2.5 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 KXS10063.1 - 2e-10 40.2 0.0 0.00013 21.6 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain Prok-RING_4 PF14447.6 KXS10063.1 - 1.4e-09 37.7 7.6 2.2e-09 37.0 7.6 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KXS10063.1 - 5.4e-07 29.9 7.7 8.3e-07 29.3 7.7 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KXS10063.1 - 1.7e-06 27.8 7.8 2.6e-06 27.3 7.8 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KXS10063.1 - 1.9e-05 24.4 7.7 3e-05 23.8 7.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXS10063.1 - 4.3e-05 23.3 8.8 6.6e-05 22.7 8.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) SHD1 PF03983.12 KXS10063.1 - 0.0012 18.6 0.0 0.0044 16.8 0.0 1.8 1 1 0 1 1 1 1 SLA1 homology domain 1, SHD1 zf-P11 PF03854.14 KXS10063.1 - 0.006 16.2 2.3 0.013 15.1 2.3 1.6 1 0 0 1 1 1 1 P-11 zinc finger zf-RING_UBOX PF13445.6 KXS10063.1 - 0.062 13.3 4.0 0.73 9.9 4.7 2.2 1 1 1 2 2 2 0 RING-type zinc-finger zf-RING_4 PF14570.6 KXS10063.1 - 0.27 11.0 7.2 0.46 10.3 7.2 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 KXS10063.1 - 0.42 10.8 4.5 0.92 9.7 4.5 1.6 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING DZR PF12773.7 KXS10063.1 - 1.2 9.2 6.9 2.1 8.4 6.9 1.4 1 0 0 1 1 1 0 Double zinc ribbon Ribosomal_L21e PF01157.18 KXS10064.1 - 5.6e-47 157.7 3.3 9.9e-47 157.0 3.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L21e S4 PF01479.25 KXS10065.1 - 1.1e-10 41.1 1.2 1.1e-10 41.1 1.2 2.3 2 0 0 2 2 2 1 S4 domain Ribosomal_S4 PF00163.19 KXS10065.1 - 1.1e-05 26.2 0.2 3e-05 24.9 0.0 1.8 1 1 1 2 2 2 1 Ribosomal protein S4/S9 N-terminal domain Slu7 PF11708.8 KXS10066.1 - 2.8e-104 348.6 10.3 2.8e-104 348.6 10.3 1.7 2 0 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor Cnl2_NKP2 PF09447.10 KXS10066.1 - 0.043 14.0 0.2 0.097 12.8 0.2 1.6 1 0 0 1 1 1 0 Cnl2/NKP2 family protein zf-CCHC_4 PF14392.6 KXS10066.1 - 0.1 12.4 0.6 0.19 11.5 0.6 1.4 1 0 0 1 1 1 0 Zinc knuckle SF3b10 PF07189.11 KXS10067.1 - 3.8e-38 129.4 0.0 4.4e-38 129.2 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) Utp21 PF04192.12 KXS10068.1 - 6.5e-46 156.7 0.0 9.3e-46 156.2 0.0 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.32 KXS10068.1 - 1.1e-22 79.8 26.1 3.4e-09 37.2 0.2 10.3 12 0 0 12 12 12 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXS10068.1 - 2.5e-20 72.6 0.1 3.4e-06 27.3 0.0 8.2 3 2 4 8 8 8 3 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 KXS10068.1 - 0.0001 21.2 0.2 0.5 9.1 0.0 3.3 2 1 1 3 3 3 2 Nup133 N terminal like Cytochrom_D1 PF02239.16 KXS10068.1 - 0.0011 17.6 0.1 0.0046 15.5 0.0 2.1 2 1 1 3 3 3 1 Cytochrome D1 heme domain WD40_like PF17005.5 KXS10068.1 - 0.0082 15.5 0.0 0.17 11.2 0.0 2.7 4 0 0 4 4 4 1 WD40-like domain Ge1_WD40 PF16529.5 KXS10068.1 - 0.011 14.7 0.1 4.6 6.1 0.0 3.5 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein RAB3GAP2_N PF14655.6 KXS10068.1 - 0.11 11.8 0.5 2.8 7.1 0.1 3.0 3 0 0 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus GxGYxYP_C PF14323.6 KXS10068.1 - 0.19 11.5 0.0 23 4.7 0.0 2.6 3 0 0 3 3 3 0 GxGYxYP putative glycoside hydrolase C-terminal domain FANCI_S1 PF14675.6 KXS10069.1 - 0.0046 16.6 0.0 0.006 16.2 0.0 1.1 1 0 0 1 1 1 1 FANCI solenoid 1 SARS_3b PF12383.8 KXS10069.1 - 0.062 13.4 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 Severe acute respiratory syndrome coronavirus 3b protein PP-binding PF00550.25 KXS10070.1 - 1.1e-10 41.7 0.1 1.6e-10 41.2 0.1 1.4 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 KXS10070.1 - 0.099 12.9 0.1 0.13 12.5 0.1 1.2 1 0 0 1 1 1 0 Acyl-carrier Dpy-30 PF05186.13 KXS10071.1 - 6e-12 45.0 0.1 9e-12 44.5 0.1 1.3 1 0 0 1 1 1 1 Dpy-30 motif DKCLD PF08068.12 KXS10073.1 - 1.1e-34 118.3 1.0 8.1e-33 112.3 0.4 3.0 3 0 0 3 3 3 1 DKCLD (NUC011) domain TruB_N PF01509.18 KXS10073.1 - 8.4e-25 87.9 0.3 7.7e-22 78.3 0.3 3.3 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 KXS10073.1 - 1.8e-22 79.3 1.2 3.3e-22 78.4 1.2 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain PUA PF01472.20 KXS10073.1 - 6.4e-21 74.1 1.6 1.1e-20 73.3 1.6 1.4 1 0 0 1 1 1 1 PUA domain UPF0113 PF03657.13 KXS10073.1 - 0.00023 21.4 0.0 0.00056 20.1 0.0 1.6 1 0 0 1 1 1 1 UPF0113 PUA domain MMS19_N PF14500.6 KXS10074.1 - 6.1e-76 255.4 1.3 4.3e-74 249.4 0.0 3.3 3 1 0 3 3 3 1 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.8 KXS10074.1 - 4.5e-69 233.6 13.4 6.2e-67 226.6 8.4 4.1 4 2 0 4 4 4 1 RNAPII transcription regulator C-terminal Cnd1 PF12717.7 KXS10074.1 - 5.7e-05 23.2 5.9 1.9 8.5 0.0 4.8 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 KXS10074.1 - 0.0037 17.7 17.2 0.012 16.1 0.4 6.9 6 1 1 7 7 7 1 HEAT-like repeat HEAT_2 PF13646.6 KXS10074.1 - 0.014 15.7 6.0 6.7 7.2 0.1 5.2 3 1 2 5 5 5 0 HEAT repeats UME PF08064.13 KXS10074.1 - 0.065 13.1 0.9 1.9 8.5 0.0 3.8 4 0 0 4 4 4 0 UME (NUC010) domain Rcd1 PF04078.13 KXS10074.1 - 0.12 11.7 2.4 0.48 9.7 0.2 2.9 3 0 0 3 3 3 0 Cell differentiation family, Rcd1-like V-ATPase_H_N PF03224.14 KXS10074.1 - 0.26 10.5 7.3 4.5 6.5 0.2 3.6 4 0 0 4 4 4 0 V-ATPase subunit H HEAT PF02985.22 KXS10074.1 - 0.47 10.9 13.2 18 5.9 0.2 5.8 7 0 0 7 7 6 0 HEAT repeat Adaptin_N PF01602.20 KXS10074.1 - 2.9 6.3 9.5 7.2 5.0 1.0 3.0 3 1 0 3 3 3 0 Adaptin N terminal region DUF3349 PF11829.8 KXS10074.1 - 3.1 8.6 5.4 15 6.5 0.1 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF3349) DUF5582 PF17819.1 KXS10075.1 - 3.3e-05 24.4 0.9 5.5e-05 23.6 0.3 1.6 2 0 0 2 2 2 1 Family of unknown function (DUF5582) EF-hand_6 PF13405.6 KXS10075.1 - 0.00085 19.1 0.0 0.0019 18.0 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.32 KXS10075.1 - 0.0014 18.0 0.0 0.0024 17.3 0.0 1.5 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 KXS10075.1 - 0.015 15.7 0.1 0.022 15.2 0.1 1.3 1 1 0 1 1 1 0 EF-hand domain pair EF-hand_8 PF13833.6 KXS10075.1 - 0.016 15.0 0.0 0.026 14.4 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain pair FF PF01846.19 KXS10076.1 - 1.4e-50 169.2 21.2 2e-13 50.3 0.1 6.0 5 0 0 5 5 5 5 FF domain WW PF00397.26 KXS10076.1 - 2.4e-16 59.5 19.7 8.1e-09 35.4 2.5 3.1 3 0 0 3 3 3 2 WW domain RhoGAP-FF1 PF16512.5 KXS10076.1 - 2.4e-05 24.9 19.8 0.0017 19.0 1.5 4.8 4 1 1 5 5 5 2 p190-A and -B Rho GAPs FF domain SelB-wing_2 PF09106.11 KXS10076.1 - 0.019 15.2 0.2 0.073 13.3 0.2 2.1 1 0 0 1 1 1 0 Elongation factor SelB, winged helix Peptidase_C10 PF01640.17 KXS10076.1 - 0.11 12.8 1.1 0.37 11.1 0.5 2.2 2 0 0 2 2 2 0 Peptidase C10 family Glyco_hyd_101C PF17451.2 KXS10076.1 - 0.49 10.7 13.3 2.6 8.3 2.5 3.1 2 1 1 3 3 3 0 Glycosyl hydrolase 101 beta sandwich domain zf-TRAF PF02176.18 KXS10077.1 - 2e-15 57.2 18.8 2.4e-08 34.6 2.5 4.0 1 1 2 3 3 3 3 TRAF-type zinc finger zf-C3HC4_2 PF13923.6 KXS10077.1 - 9.1e-07 28.6 7.7 9.1e-07 28.6 7.7 2.8 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXS10077.1 - 3.8e-05 23.6 9.9 3.8e-05 23.6 9.9 2.7 2 1 0 2 2 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 KXS10077.1 - 4.5e-05 23.7 6.9 4.5e-05 23.7 6.9 3.7 2 1 1 3 3 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KXS10077.1 - 9.2e-05 22.2 5.3 9.2e-05 22.2 5.3 3.1 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-TRAF_2 PF15965.5 KXS10077.1 - 0.00011 22.5 20.0 0.00023 21.5 0.7 4.0 2 1 2 4 4 4 1 TRAF-like zinc-finger zf-RING_5 PF14634.6 KXS10077.1 - 0.00012 22.0 6.7 0.00012 22.0 6.7 2.7 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KXS10077.1 - 0.00014 21.6 7.7 0.00014 21.6 7.7 3.0 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KXS10077.1 - 0.0003 20.9 6.4 0.0003 20.9 6.4 2.6 2 1 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 KXS10077.1 - 0.0072 16.4 5.0 0.0072 16.4 5.0 2.5 2 1 1 3 3 1 1 zinc RING finger of MSL2 HALZ PF02183.18 KXS10077.1 - 0.008 16.4 0.2 1.5 9.1 0.0 2.7 2 0 0 2 2 2 1 Homeobox associated leucine zipper Sina PF03145.16 KXS10077.1 - 0.0082 16.1 12.2 3.5 7.5 1.0 3.9 1 1 3 4 4 4 2 Seven in absentia protein family Zn-ribbon_8 PF09723.10 KXS10077.1 - 0.0096 16.0 2.4 0.0096 16.0 2.4 3.0 2 1 0 2 2 1 1 Zinc ribbon domain zf-rbx1 PF12678.7 KXS10077.1 - 0.013 15.8 5.3 0.013 15.8 5.3 2.7 2 1 0 2 2 1 0 RING-H2 zinc finger domain zf-ACC PF17848.1 KXS10077.1 - 0.094 12.8 6.7 4.9 7.3 0.1 3.7 3 0 0 3 3 3 0 Acetyl-coA carboxylase zinc finger domain KASH_CCD PF14662.6 KXS10077.1 - 0.28 11.0 2.8 4.3 7.1 0.0 2.2 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH PRKG1_interact PF15898.5 KXS10077.1 - 0.29 12.1 1.0 23 6.0 0.0 2.4 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain zinc-ribbons_6 PF07191.12 KXS10077.1 - 0.45 10.5 12.1 0.47 10.5 2.7 2.6 2 0 0 2 2 2 0 zinc-ribbons Csm1_N PF18504.1 KXS10077.1 - 0.46 10.9 3.3 2.4 8.6 0.2 2.5 2 0 0 2 2 2 0 Csm1 N-terminal domain zf-DNA_Pol PF08996.10 KXS10077.1 - 5.6 6.7 11.3 0.21 11.4 3.2 2.3 1 1 1 2 2 2 0 DNA Polymerase alpha zinc finger Ribosomal_L50 PF10501.9 KXS10078.1 - 6e-06 26.4 0.0 9.2e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal subunit 39S ATP-synt_F6 PF05511.11 KXS10078.1 - 0.15 12.4 0.0 1.2 9.6 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial ATP synthase coupling factor 6 Acyltransferase PF01553.21 KXS10079.1 - 2.9e-16 59.3 0.0 4.3e-16 58.8 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 KXS10079.1 - 1.3e-11 44.4 0.0 3.1e-11 43.2 0.0 1.6 1 0 0 1 1 1 1 Acyltransferase C-terminus Mt_ATP-synt_B PF05405.14 KXS10080.1 - 1.1e-34 119.4 4.5 1.3e-34 119.2 4.5 1.0 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF4349 PF14257.6 KXS10080.1 - 0.0021 17.5 4.2 0.0038 16.7 3.7 1.8 1 1 1 2 2 2 1 Domain of unknown function (DUF4349) BLUF PF04940.12 KXS10080.1 - 0.077 13.1 0.1 0.17 12.0 0.1 1.6 1 0 0 1 1 1 0 Sensors of blue-light using FAD GPS2_interact PF15784.5 KXS10080.1 - 0.086 13.3 0.2 0.086 13.3 0.2 1.9 3 0 0 3 3 3 0 G-protein pathway suppressor 2-interacting domain PET117 PF15786.5 KXS10081.1 - 1.5e-14 54.0 0.5 1.8e-14 53.8 0.5 1.0 1 0 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial ERCC4 PF02732.15 KXS10082.1 - 7.2e-23 81.5 0.0 1.1e-22 80.9 0.0 1.3 1 0 0 1 1 1 1 ERCC4 domain HHH_8 PF14716.6 KXS10082.1 - 5.4e-05 23.5 0.0 0.00011 22.5 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain Collagen PF01391.18 KXS10082.1 - 0.0015 18.3 14.5 0.0031 17.2 14.5 1.4 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) RRM_1 PF00076.22 KXS10083.1 - 5.9e-17 61.3 0.1 1.5e-11 43.9 0.0 3.3 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KXS10083.1 - 0.019 15.1 0.0 0.18 11.9 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif PHM7_cyt PF14703.6 KXS10083.1 - 0.12 12.6 0.2 12 6.1 0.0 3.1 2 2 1 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter AC_N PF16214.5 KXS10083.1 - 2.4 7.2 4.6 4 6.5 4.6 1.3 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region SH3_1 PF00018.28 KXS10084.1 - 1.7e-20 72.4 0.1 1.2e-09 37.6 0.0 2.4 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 KXS10084.1 - 4.1e-20 71.2 0.1 1.7e-09 37.2 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_9 PF14604.6 KXS10084.1 - 1.5e-17 63.1 0.1 4.9e-08 32.7 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SAM_2 PF07647.17 KXS10084.1 - 2.9e-13 49.7 0.0 4.4e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KXS10084.1 - 3.3e-13 49.9 0.0 5.8e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.23 KXS10084.1 - 1.7e-06 28.6 0.0 2.8e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SH3_3 PF08239.11 KXS10084.1 - 0.0011 19.2 8.1 0.04 14.2 0.2 3.4 3 0 0 3 3 3 2 Bacterial SH3 domain SH3_10 PF17902.1 KXS10084.1 - 0.017 15.2 0.0 0.22 11.6 0.0 2.3 2 0 0 2 2 2 0 SH3 domain SAM_4 PF18017.1 KXS10084.1 - 0.04 13.9 0.0 0.075 13.0 0.0 1.3 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) SDA1 PF05285.12 KXS10085.1 - 0.0088 15.5 25.6 0.01 15.3 25.6 1.1 1 0 0 1 1 1 1 SDA1 Mucin-like PF16058.5 KXS10085.1 - 1.7 8.8 17.9 0.88 9.7 15.6 1.8 1 1 0 1 1 1 0 Mucin-like RRM_1 PF00076.22 KXS10086.1 - 1.2e-08 34.7 0.0 1.6e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KXS10086.1 - 0.0023 18.0 0.0 0.0028 17.8 0.0 1.3 1 1 0 1 1 1 1 RNA recognition motif Alg14 PF08660.11 KXS10087.1 - 3.5e-63 212.7 0.0 4.5e-63 212.3 0.0 1.1 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like Sds3 PF08598.11 KXS10088.1 - 4e-20 72.7 1.1 4.9e-20 72.5 0.3 1.5 2 0 0 2 2 2 1 Sds3-like APC_u14 PF16635.5 KXS10088.1 - 0.12 12.9 0.0 0.52 10.9 0.0 2.0 2 0 0 2 2 2 0 Unstructured region on APC between SAMP and APC_crr PX PF00787.24 KXS10089.1 - 1e-17 64.1 0.0 2.2e-17 63.1 0.0 1.5 1 0 0 1 1 1 1 PX domain DUF2461 PF09365.10 KXS10090.1 - 7e-64 215.6 0.6 1.1e-63 215.0 0.6 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein (DUF2461) DUF4778 PF16008.5 KXS10090.1 - 0.11 12.5 3.8 0.16 12.0 3.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) MFMR_assoc PF16596.5 KXS10090.1 - 0.95 9.9 9.5 1.8 9.0 9.5 1.4 1 0 0 1 1 1 0 Disordered region downstream of MFMR DUF913 PF06025.12 KXS10090.1 - 0.99 8.3 6.5 1.4 7.8 6.5 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) CDC45 PF02724.14 KXS10090.1 - 9.1 4.4 15.1 12 4.1 15.1 1.1 1 0 0 1 1 1 0 CDC45-like protein STT3 PF02516.14 KXS10091.1 - 2.7e-140 468.5 30.9 7.9e-136 453.8 27.9 2.4 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit SH3_1 PF00018.28 KXS10092.1 - 1.4e-35 120.6 5.4 6.3e-18 64.1 0.1 3.1 3 0 0 3 3 3 2 SH3 domain SH3_9 PF14604.6 KXS10092.1 - 5.6e-33 112.6 2.0 5.1e-16 58.3 0.1 3.0 3 0 0 3 3 3 2 Variant SH3 domain Cofilin_ADF PF00241.20 KXS10092.1 - 5.2e-23 81.1 0.0 9.8e-23 80.2 0.0 1.5 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein SH3_2 PF07653.17 KXS10092.1 - 4.3e-21 74.3 0.3 4.8e-10 39.0 0.0 3.5 3 0 0 3 3 3 2 Variant SH3 domain Evr1_Alr PF04777.13 KXS10093.1 - 8.6e-25 87.1 0.5 1.1e-24 86.7 0.5 1.2 1 0 0 1 1 1 1 Erv1 / Alr family SNAD4 PF18750.1 KXS10093.1 - 0.1 12.7 0.1 0.14 12.3 0.1 1.2 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 Actin PF00022.19 KXS10095.1 - 3.6e-117 391.4 0.0 3e-116 388.4 0.0 1.9 1 1 0 1 1 1 1 Actin FAD_binding_3 PF01494.19 KXS10096.1 - 1.3e-16 60.8 2.3 1.5e-15 57.3 2.3 2.2 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KXS10096.1 - 1.1e-06 28.5 0.4 0.00014 21.5 0.1 2.3 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXS10096.1 - 2.9e-05 24.2 0.4 8.3e-05 22.7 0.4 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KXS10096.1 - 7.5e-05 21.6 0.1 0.00011 21.0 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.14 KXS10096.1 - 0.00016 21.0 0.1 0.00024 20.4 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXS10096.1 - 0.00041 20.8 0.1 0.008 16.7 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXS10096.1 - 0.00092 18.4 0.2 0.0015 17.7 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain ApbA PF02558.16 KXS10096.1 - 0.018 14.7 0.1 0.034 13.8 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.6 KXS10096.1 - 0.02 14.1 0.0 0.031 13.5 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KXS10096.1 - 0.029 13.4 0.1 0.038 13.1 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 KXS10096.1 - 0.042 13.1 0.1 0.074 12.3 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 KXS10096.1 - 0.055 13.0 0.0 0.093 12.3 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Glu_dehyd_C PF16912.5 KXS10096.1 - 0.11 11.9 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus FAD_oxidored PF12831.7 KXS10096.1 - 0.12 11.6 0.8 0.22 10.9 0.4 1.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase Nop53 PF07767.11 KXS10097.1 - 6.5e-81 272.7 19.2 7.8e-81 272.5 19.2 1.1 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) Merozoite_SPAM PF07133.11 KXS10097.1 - 4.4 7.3 21.7 7.5 6.5 21.7 1.3 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) RRN3 PF05327.11 KXS10097.1 - 4.9 5.6 6.4 7.7 4.9 6.4 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 RNase_H2_suC PF08615.11 KXS10098.1 - 3.3e-20 72.7 0.0 4.2e-20 72.4 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) LRR_6 PF13516.6 KXS10099.1 - 9.7e-30 100.1 17.8 0.003 17.5 0.1 9.8 9 0 0 9 9 9 7 Leucine Rich repeat Pkinase PF00069.25 KXS10099.1 - 1.6e-24 86.7 0.0 3.1e-24 85.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS10099.1 - 2.3e-24 86.1 0.0 3.9e-24 85.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXS10099.1 - 5.7e-07 29.1 0.1 2.1e-06 27.3 0.1 1.9 1 1 0 1 1 1 1 Kinase-like LRR_4 PF12799.7 KXS10099.1 - 7.1e-06 26.3 9.8 0.057 13.9 0.1 5.7 2 2 3 6 6 6 3 Leucine Rich repeats (2 copies) APH PF01636.23 KXS10099.1 - 0.00014 21.9 0.0 0.00033 20.7 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family LRR_8 PF13855.6 KXS10099.1 - 0.00032 20.4 14.1 0.048 13.4 0.2 6.1 2 2 3 5 5 5 4 Leucine rich repeat LRR_1 PF00560.33 KXS10099.1 - 0.00073 19.7 6.2 13 6.8 0.0 7.1 9 0 0 9 9 7 1 Leucine Rich Repeat Kdo PF06293.14 KXS10099.1 - 0.0018 17.6 0.0 0.0035 16.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KXS10099.1 - 0.01 15.4 0.0 0.02 14.5 0.0 1.4 1 0 0 1 1 1 0 RIO1 family DUF4347 PF14252.6 KXS10099.1 - 0.01 15.7 0.1 3.1 7.6 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4347) Choline_kinase PF01633.20 KXS10099.1 - 0.12 12.0 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase SGL PF08450.12 KXS10099.1 - 0.12 11.9 0.0 0.28 10.7 0.0 1.5 1 0 0 1 1 1 0 SMP-30/Gluconolactonase/LRE-like region Ribosomal_L21p PF00829.21 KXS10100.1 - 3.2e-15 56.2 0.2 4e-15 55.9 0.2 1.1 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein MTABC_N PF16185.5 KXS10102.1 - 0.14 11.6 4.2 0.031 13.8 0.8 1.8 2 0 0 2 2 2 0 Mitochondrial ABC-transporter N-terminal five TM region PIRT PF15099.6 KXS10102.1 - 2.7 7.6 6.8 1.9 8.1 3.0 2.7 2 1 0 2 2 2 0 Phosphoinositide-interacting protein family Inositol_P PF00459.25 KXS10103.1 - 3.1e-65 220.4 0.0 3.6e-65 220.2 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family NAD_Gly3P_dh_C PF07479.14 KXS10104.1 - 2.3e-45 154.4 0.6 3.1e-45 153.9 0.6 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.23 KXS10104.1 - 9.1e-35 120.0 0.0 1.5e-34 119.3 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.17 KXS10104.1 - 3.5e-07 30.7 0.0 1.7e-06 28.5 0.0 2.2 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 KXS10104.1 - 7.3e-05 22.5 0.0 0.00013 21.6 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.14 KXS10104.1 - 9.1e-05 22.1 0.0 0.00015 21.4 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.18 KXS10104.1 - 0.00029 21.1 0.0 0.00087 19.5 0.0 1.9 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_2 PF03446.15 KXS10104.1 - 0.00093 19.4 0.0 0.0034 17.6 0.0 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_8 PF13450.6 KXS10104.1 - 0.0013 18.9 0.0 0.0029 17.8 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXS10104.1 - 0.0051 16.1 0.0 0.2 10.9 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase XdhC_C PF13478.6 KXS10104.1 - 0.017 15.6 0.0 0.05 14.1 0.0 1.9 1 0 0 1 1 1 0 XdhC Rossmann domain AlaDh_PNT_C PF01262.21 KXS10104.1 - 0.032 13.5 0.0 0.057 12.7 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 KXS10104.1 - 0.058 12.8 0.0 0.24 10.7 0.0 2.0 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox PF00070.27 KXS10104.1 - 0.06 13.9 0.0 0.31 11.6 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXS10104.1 - 0.073 12.6 0.0 0.17 11.5 0.0 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase 3HCDH_N PF02737.18 KXS10104.1 - 0.084 12.7 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 KXS10104.1 - 0.098 12.9 0.0 0.58 10.4 0.0 2.1 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 KXS10104.1 - 0.1 12.7 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 KXS10104.1 - 0.13 12.7 0.0 0.31 11.5 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Beta_elim_lyase PF01212.21 KXS10105.1 - 1.5e-51 175.4 0.0 2e-51 175.0 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Chromate_transp PF02417.15 KXS10108.1 - 2.3e-24 86.3 11.5 3.8e-24 85.6 11.5 1.3 1 0 0 1 1 1 1 Chromate transporter DUF3938 PF13074.6 KXS10108.1 - 0.18 12.1 0.3 0.57 10.5 0.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3938) DUF1752 PF08550.10 KXS10109.1 - 1.3e-08 34.5 4.3 1.8e-08 34.0 4.3 1.2 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) MFS_1 PF07690.16 KXS10110.1 - 1.4e-46 159.1 49.3 1.4e-46 159.1 49.3 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KXS10110.1 - 4.7e-18 65.0 19.8 4.7e-18 65.0 19.8 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KXS10110.1 - 3.2e-11 42.7 12.6 3.2e-11 42.7 12.6 2.7 2 1 0 2 2 2 2 Sugar (and other) transporter OATP PF03137.20 KXS10110.1 - 3 6.0 23.2 0.043 12.1 2.9 3.3 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family adh_short_C2 PF13561.6 KXS10111.1 - 3.4e-52 177.3 1.9 1.2e-51 175.6 1.9 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXS10111.1 - 3.7e-41 140.7 3.4 1.1e-40 139.1 3.4 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXS10111.1 - 2.7e-06 27.4 0.3 6e-06 26.3 0.3 1.5 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 KXS10111.1 - 2.1e-05 23.7 0.9 0.0091 15.0 0.4 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KXS10111.1 - 0.0027 17.2 1.5 0.025 14.0 1.5 2.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 KXS10111.1 - 0.0089 15.9 0.3 0.015 15.2 0.3 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KXS10111.1 - 0.034 14.2 0.2 0.18 11.9 0.2 2.1 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Methyltransf_PK PF05891.12 KXS10111.1 - 0.13 11.8 0.1 0.22 11.0 0.1 1.3 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase ELMO_CED12 PF04727.13 KXS10112.1 - 1.6e-30 106.5 0.0 2e-30 106.2 0.0 1.1 1 0 0 1 1 1 1 ELMO/CED-12 family FA_desaturase PF00487.24 KXS10113.1 - 4.3e-28 98.8 24.6 5.8e-28 98.4 24.6 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 KXS10113.1 - 3.9e-13 49.3 0.0 8.4e-13 48.3 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Pkinase PF00069.25 KXS10116.1 - 1.6e-62 211.3 0.0 2e-62 210.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS10116.1 - 4.8e-31 108.0 0.0 6e-31 107.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KXS10116.1 - 0.0014 18.0 0.0 0.0022 17.4 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KXS10116.1 - 0.0019 17.6 0.0 0.56 9.5 0.0 2.6 3 0 0 3 3 3 2 Kinase-like Pkinase_fungal PF17667.1 KXS10116.1 - 0.0057 15.5 0.0 0.012 14.4 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KXS10116.1 - 0.021 14.8 0.3 2.5 7.9 1.3 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family FTA2 PF13095.6 KXS10116.1 - 0.13 11.9 0.1 0.53 9.9 0.1 2.0 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 bZIP_2 PF07716.15 KXS10118.1 - 3.4e-09 36.6 12.4 3.4e-09 36.6 12.4 2.1 1 1 1 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 KXS10118.1 - 1.2e-08 34.9 11.2 1.2e-08 34.9 11.2 1.7 1 1 0 1 1 1 1 bZIP transcription factor Nucleo_P87 PF07267.11 KXS10118.1 - 0.019 13.9 0.0 0.02 13.8 0.0 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF3763 PF12592.8 KXS10118.1 - 0.12 12.5 1.4 1.2 9.3 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3763) Fez1 PF06818.15 KXS10118.1 - 0.2 12.1 12.5 0.29 11.5 12.5 1.2 1 0 0 1 1 1 0 Fez1 bZIP_Maf PF03131.17 KXS10118.1 - 1.2 9.8 16.4 4.5 7.9 16.4 1.9 1 1 0 1 1 1 0 bZIP Maf transcription factor DUF572 PF04502.13 KXS10118.1 - 2.1 7.9 12.5 3 7.4 12.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF4407 PF14362.6 KXS10118.1 - 2.7 7.3 8.7 3.8 6.8 8.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) UQ_con PF00179.26 KXS10119.1 - 2.3e-46 156.9 0.0 2.6e-46 156.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KXS10119.1 - 0.00054 19.7 0.0 0.00067 19.4 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KXS10119.1 - 0.0053 17.0 0.0 0.0054 17.0 0.0 1.4 1 1 0 1 1 1 1 RWD domain YEATS PF03366.16 KXS10120.1 - 3.5e-31 107.0 0.2 5.8e-31 106.3 0.2 1.4 1 0 0 1 1 1 1 YEATS family DivIC PF04977.15 KXS10120.1 - 0.025 14.3 1.2 0.042 13.6 1.2 1.4 1 0 0 1 1 1 0 Septum formation initiator Pyridoxal_deC PF00282.19 KXS10121.1 - 1.2e-15 57.1 0.0 1.2e-14 53.9 0.0 2.0 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 KXS10121.1 - 1.3e-09 37.6 0.0 9.1e-09 34.7 0.0 2.2 2 1 0 2 2 2 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 KXS10121.1 - 1.3e-05 24.6 0.0 0.00016 21.0 0.0 2.1 1 1 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 KXS10121.1 - 0.00022 20.7 0.0 0.00036 20.0 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Ala_racemase_C PF00842.21 KXS10122.1 - 0.016 15.0 0.1 0.22 11.3 0.1 2.3 2 0 0 2 2 2 0 Alanine racemase, C-terminal domain DUF3287 PF11690.8 KXS10122.1 - 0.12 12.1 0.1 0.62 9.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3287) SH3_1 PF00018.28 KXS10123.1 - 0.0011 18.5 0.1 0.0037 16.8 0.0 1.9 2 0 0 2 2 2 1 SH3 domain NUFIP1 PF10453.9 KXS10123.1 - 0.084 12.7 0.1 0.23 11.3 0.1 1.7 1 0 0 1 1 1 0 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) Alpha_kinase PF02816.18 KXS10126.1 - 5.6e-26 91.8 0.0 1.1e-25 90.9 0.0 1.5 1 0 0 1 1 1 1 Alpha-kinase family DUF2258 PF10015.9 KXS10126.1 - 0.04 14.1 0.1 0.12 12.5 0.1 1.9 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2258) LPD1 PF18796.1 KXS10126.1 - 0.044 13.9 0.8 0.51 10.5 0.0 2.5 2 0 0 2 2 2 0 Large polyvalent protein-associated domain 1 HALZ PF02183.18 KXS10126.1 - 0.49 10.7 0.1 0.49 10.7 0.1 2.9 4 0 0 4 4 4 0 Homeobox associated leucine zipper TMF_DNA_bd PF12329.8 KXS10126.1 - 6.9 6.7 12.2 2.5 8.2 2.5 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding ZapB PF06005.12 KXS10126.1 - 8.4 6.9 11.5 0.57 10.7 1.6 2.8 2 1 1 3 3 3 0 Cell division protein ZapB DUF4164 PF13747.6 KXS10127.1 - 0.0015 18.8 4.3 0.0015 18.8 4.3 3.8 2 2 1 3 3 3 1 Domain of unknown function (DUF4164) CENP-F_leu_zip PF10473.9 KXS10127.1 - 0.006 16.6 16.0 0.0081 16.2 7.7 2.4 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.6 KXS10127.1 - 0.027 13.8 0.6 0.027 13.8 0.6 2.9 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 KXS10127.1 - 2.8 6.8 17.1 0.15 10.9 7.8 2.6 2 1 1 3 3 3 0 Spc7 kinetochore protein Fez1 PF06818.15 KXS10127.1 - 4.6 7.6 15.5 0.83 10.1 8.5 2.2 2 0 0 2 2 2 0 Fez1 THOC7 PF05615.13 KXS10127.1 - 5.6 7.3 16.1 5.9 7.2 8.3 3.1 2 1 0 2 2 2 0 Tho complex subunit 7 DUF2968 PF11180.8 KXS10127.1 - 8.6 6.0 13.6 1.8 8.2 6.7 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF2968) APG6_N PF17675.1 KXS10127.1 - 9.9 6.7 21.8 30 5.2 2.3 3.4 2 1 0 2 2 2 0 Apg6 coiled-coil region VWA_2 PF13519.6 KXS10129.1 - 0.00027 21.5 0.0 0.00058 20.5 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain MINDY_DUB PF04424.13 KXS10129.1 - 0.036 14.1 0.0 0.067 13.2 0.0 1.4 1 0 0 1 1 1 0 MINDY deubiquitinase GTP_EFTU PF00009.27 KXS10131.1 - 6.2e-56 189.0 0.0 8.7e-56 188.5 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 KXS10131.1 - 7.2e-23 80.5 0.0 1.2e-22 79.7 0.0 1.4 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 KXS10131.1 - 3.4e-17 62.2 0.0 7.9e-17 61.1 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus RF3_C PF16658.5 KXS10131.1 - 1.2e-07 31.6 0.0 2.3e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain EFG_IV PF03764.18 KXS10131.1 - 0.00028 20.6 0.0 0.00063 19.5 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV GTP_EFTU_D2 PF03144.25 KXS10131.1 - 0.061 13.7 0.0 0.27 11.7 0.0 2.2 1 1 0 1 1 1 0 Elongation factor Tu domain 2 Phage_Mu_Gam PF07352.12 KXS10132.1 - 0.05 13.5 0.8 0.05 13.5 0.8 2.2 2 1 0 2 2 2 0 Bacteriophage Mu Gam like protein Sds3 PF08598.11 KXS10132.1 - 0.2 11.6 8.2 0.26 11.2 8.2 1.2 1 0 0 1 1 1 0 Sds3-like YabA PF06156.13 KXS10132.1 - 0.24 12.1 0.2 0.24 12.1 0.2 2.9 1 1 2 3 3 3 0 Initiation control protein YabA GSH_synth_ATP PF03917.17 KXS10133.1 - 3.8e-127 424.1 0.0 4.3e-127 424.0 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 KXS10133.1 - 1.1e-33 115.7 0.0 2.1e-33 114.9 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic glutathione synthase Sel1 PF08238.12 KXS10134.1 - 0.00028 21.5 3.4 0.00056 20.5 3.4 1.5 1 0 0 1 1 1 1 Sel1 repeat SWIRM PF04433.17 KXS10136.1 - 1.2e-06 28.7 0.0 2.3e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 SWIRM domain F-box-like PF12937.7 KXS10137.1 - 0.0016 18.3 0.0 0.004 17.0 0.0 1.7 1 0 0 1 1 1 1 F-box-like Spermine_synth PF01564.17 KXS10139.1 - 7.2e-06 25.5 0.0 1.1e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Methyltransf_25 PF13649.6 KXS10139.1 - 0.00054 20.6 0.0 0.0012 19.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXS10139.1 - 0.01 16.4 0.1 0.029 15.0 0.1 1.8 1 0 0 1 1 1 0 Methyltransferase domain YABBY PF04690.13 KXS10140.1 - 2.5e-17 63.9 1.0 2.9e-17 63.7 1.0 1.1 1 0 0 1 1 1 1 YABBY protein Ccdc124 PF06244.12 KXS10140.1 - 1.2e-07 32.3 0.7 1.5e-07 32.1 0.7 1.3 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 124 /Oxs1 HMG_box PF00505.19 KXS10140.1 - 1.9e-05 25.0 0.4 3.7e-05 24.1 0.4 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KXS10140.1 - 0.011 16.4 0.7 0.018 15.6 0.5 1.5 1 1 0 1 1 1 0 HMG-box domain Pkinase PF00069.25 KXS10141.1 - 1.5e-63 214.7 0.0 1.9e-63 214.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS10141.1 - 1.9e-20 73.3 0.0 2.6e-20 72.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXS10141.1 - 0.00025 20.5 0.0 0.00046 19.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KXS10141.1 - 0.014 15.3 0.0 0.032 14.2 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 KXS10141.1 - 0.031 13.6 0.0 0.056 12.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KXS10141.1 - 0.068 12.8 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase AMP-binding PF00501.28 KXS10142.1 - 3.8e-79 266.3 0.1 4.9e-79 265.9 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXS10142.1 - 4.4e-26 91.7 0.1 9.2e-26 90.6 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 KXS10142.1 - 1.3e-15 57.0 0.7 4.9e-15 55.2 0.4 2.2 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus Carn_acyltransf PF00755.20 KXS10143.1 - 3.6e-181 603.8 0.0 4.3e-181 603.5 0.0 1.1 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase LRR_8 PF13855.6 KXS10144.1 - 1.5e-11 43.9 4.8 1.7e-10 40.5 2.4 2.3 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KXS10144.1 - 6e-10 39.2 8.3 2.9e-06 27.5 3.5 3.3 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) SH3_9 PF14604.6 KXS10144.1 - 1.4e-05 24.9 0.1 3.2e-05 23.7 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain LRR_1 PF00560.33 KXS10144.1 - 0.00018 21.6 3.1 9.7 7.2 0.1 4.9 4 0 0 4 4 4 1 Leucine Rich Repeat SH3_1 PF00018.28 KXS10144.1 - 0.0009 18.8 0.0 0.0018 17.8 0.0 1.5 1 0 0 1 1 1 1 SH3 domain LRR_6 PF13516.6 KXS10144.1 - 0.008 16.2 6.6 4.4 7.6 0.1 4.4 4 0 0 4 4 4 1 Leucine Rich repeat SH3_2 PF07653.17 KXS10144.1 - 0.022 14.5 0.0 0.048 13.3 0.0 1.6 1 0 0 1 1 1 0 Variant SH3 domain Adeno_E3_CR2 PF02439.15 KXS10144.1 - 0.064 13.0 2.1 0.13 12.0 2.1 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Hpt PF01627.23 KXS10146.1 - 9.6e-10 38.6 0.4 1.9e-09 37.6 0.0 1.7 2 1 0 2 2 2 1 Hpt domain Hpt PF01627.23 KXS10147.1 - 4.7e-10 39.6 0.1 7.6e-10 38.9 0.1 1.3 1 0 0 1 1 1 1 Hpt domain PRESAN PF09687.10 KXS10147.1 - 0.077 13.5 0.0 12 6.5 0.0 2.3 2 0 0 2 2 2 0 Plasmodium RESA N-terminal Telomere_reg-2 PF10193.9 KXS10147.1 - 0.12 12.9 0.1 0.34 11.4 0.1 1.8 2 0 0 2 2 2 0 Telomere length regulation protein ETF_QO PF05187.13 KXS10148.1 - 4.7e-37 126.3 0.0 9.1e-37 125.4 0.0 1.5 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S DAO PF01266.24 KXS10148.1 - 3.1e-10 40.2 0.2 4.1e-06 26.6 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KXS10148.1 - 3e-09 36.5 1.4 3.2e-05 23.2 2.2 2.2 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.17 KXS10148.1 - 2e-08 33.7 0.3 3.2e-05 23.3 0.1 2.4 3 0 0 3 3 3 2 Thi4 family NAD_binding_8 PF13450.6 KXS10148.1 - 5e-07 29.8 0.0 1.5e-06 28.3 0.0 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXS10148.1 - 5.4e-07 29.1 0.3 8.6e-06 25.2 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KXS10148.1 - 6.6e-06 25.6 0.2 2.3e-05 23.8 0.2 1.8 1 1 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.14 KXS10148.1 - 1e-05 24.6 0.1 0.002 17.0 0.5 2.2 2 0 0 2 2 2 2 Tryptophan halogenase Pyr_redox PF00070.27 KXS10148.1 - 3.5e-05 24.3 0.6 0.055 14.0 0.7 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXS10148.1 - 7.2e-05 22.8 0.2 0.00014 21.9 0.2 1.4 1 0 0 1 1 1 1 FAD-NAD(P)-binding HI0933_like PF03486.14 KXS10148.1 - 0.00015 20.6 0.9 0.00049 18.9 0.9 1.7 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 KXS10148.1 - 0.00033 20.1 0.0 0.00047 19.6 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KXS10148.1 - 0.00075 18.8 0.5 0.0012 18.2 0.5 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KXS10148.1 - 0.0023 17.1 0.4 0.0034 16.5 0.4 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein GIDA PF01134.22 KXS10148.1 - 0.05 12.7 0.7 0.078 12.1 0.7 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A K_oxygenase PF13434.6 KXS10148.1 - 0.061 12.5 0.0 0.098 11.8 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.21 KXS10148.1 - 0.084 12.1 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ABC_tran PF00005.27 KXS10149.1 - 1.2e-24 87.4 0.0 2.2e-24 86.5 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 KXS10149.1 - 2.8e-19 69.4 20.7 2.8e-19 69.4 20.7 1.5 2 0 0 2 2 2 1 ABC-2 type transporter AAA_21 PF13304.6 KXS10149.1 - 1.1e-05 25.4 0.1 0.041 13.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KXS10149.1 - 0.00017 21.5 0.1 0.00037 20.4 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase T2SSE PF00437.20 KXS10149.1 - 0.00036 19.7 0.1 0.0006 19.0 0.1 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_16 PF13191.6 KXS10149.1 - 0.0049 17.3 0.0 0.0086 16.5 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 KXS10149.1 - 0.0051 16.3 0.8 0.11 11.9 0.0 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain NACHT PF05729.12 KXS10149.1 - 0.014 15.3 0.0 0.03 14.2 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_28 PF13521.6 KXS10149.1 - 0.025 14.8 0.4 0.059 13.6 0.4 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KXS10149.1 - 0.032 14.0 0.5 0.094 12.5 0.5 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.6 KXS10149.1 - 0.037 13.6 0.1 0.081 12.5 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KXS10149.1 - 0.12 12.7 0.2 0.28 11.5 0.2 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KXS10149.1 - 0.15 11.8 0.3 0.28 10.9 0.3 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KXS10149.1 - 0.18 12.1 0.5 0.52 10.6 0.3 1.9 1 1 1 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KXS10149.1 - 0.18 11.9 0.2 0.42 10.7 0.2 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase ABC2_membrane_3 PF12698.7 KXS10149.1 - 1.3 8.0 20.7 2.9 6.9 20.6 1.5 1 1 0 1 1 1 0 ABC-2 family transporter protein Aminopep PF10023.9 KXS10150.1 - 0.051 12.9 0.0 0.059 12.7 0.0 1.0 1 0 0 1 1 1 0 Putative aminopeptidase fn3_2 PF16893.5 KXS10150.1 - 0.073 13.2 0.0 0.076 13.2 0.0 1.1 1 0 0 1 1 1 0 Fibronectin type III domain RVT_1 PF00078.27 KXS10150.1 - 0.21 11.1 0.0 0.21 11.0 0.0 1.0 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Cgr1 PF03879.14 KXS10151.1 - 3.9e-14 52.9 22.8 4.7e-14 52.7 22.8 1.1 1 0 0 1 1 1 1 Cgr1 family NA37 PF04245.13 KXS10151.1 - 0.76 9.2 5.8 0.88 9.0 5.8 1.1 1 0 0 1 1 1 0 37-kD nucleoid-associated bacterial protein TIG PF01833.24 KXS10153.1 - 0.0002 21.3 0.0 0.00057 19.9 0.0 1.8 1 0 0 1 1 1 1 IPT/TIG domain RTA1 PF04479.13 KXS10154.1 - 5.2e-51 173.2 10.4 7.6e-51 172.7 10.4 1.2 1 0 0 1 1 1 1 RTA1 like protein UPF0182 PF03699.13 KXS10154.1 - 0.26 9.4 3.5 0.19 9.8 2.1 1.3 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0182) Pkinase PF00069.25 KXS10155.1 - 2.9e-73 246.5 0.0 3.6e-73 246.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS10155.1 - 3.2e-36 124.9 0.0 4.5e-36 124.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXS10155.1 - 0.0018 18.2 0.3 0.0047 16.9 0.1 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXS10155.1 - 0.0019 17.1 0.0 0.0035 16.2 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KXS10155.1 - 0.0024 17.3 0.0 0.0039 16.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KXS10155.1 - 0.0068 15.8 0.0 0.02 14.3 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 KXS10155.1 - 0.086 11.8 0.1 0.13 11.2 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase WD40 PF00400.32 KXS10156.1 - 8.4e-21 73.9 9.8 0.0001 23.0 0.0 7.0 6 1 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXS10156.1 - 3.4e-13 49.7 0.0 0.0062 16.8 0.1 5.0 3 2 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KXS10156.1 - 0.00015 20.8 0.7 0.18 10.7 0.1 3.0 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KXS10156.1 - 0.00048 18.9 0.1 0.00089 18.0 0.1 1.4 1 1 0 1 1 1 1 Nucleoporin Nup120/160 PQQ_2 PF13360.6 KXS10156.1 - 0.0017 18.0 0.0 0.0034 17.0 0.0 1.5 1 1 0 1 1 1 1 PQQ-like domain PQQ_3 PF13570.6 KXS10156.1 - 0.12 12.9 1.0 0.48 11.0 0.0 2.6 2 0 0 2 2 2 0 PQQ-like domain SOG2 PF10428.9 KXS10157.1 - 1.3 8.2 10.1 1.3 8.1 10.1 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Oxidored_FMN PF00724.20 KXS10160.1 - 1.2e-51 176.0 0.0 1.5e-51 175.7 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.17 KXS10160.1 - 0.1 11.7 0.3 0.49 9.4 0.0 1.9 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) CN_hydrolase PF00795.22 KXS10161.1 - 1.2e-42 146.1 0.0 1.5e-42 145.8 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase DDE_3 PF13358.6 KXS10162.1 - 9.9e-07 28.6 0.0 1.4e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease adh_short PF00106.25 KXS10163.1 - 6.4e-08 32.3 0.3 0.0019 17.7 0.0 3.0 3 0 0 3 3 3 3 short chain dehydrogenase adh_short_C2 PF13561.6 KXS10163.1 - 0.0065 16.1 2.9 0.11 12.0 0.2 3.0 2 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Gln-synt_C PF00120.24 KXS10164.1 - 5.3e-69 232.8 0.0 7e-69 232.4 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Sigma70_r1_1 PF03979.14 KXS10164.1 - 0.041 13.9 0.0 0.69 10.0 0.0 2.4 2 0 0 2 2 2 0 Sigma-70 factor, region 1.1 GCS2 PF04107.13 KXS10164.1 - 0.054 12.8 0.2 0.8 9.0 0.0 2.3 2 1 0 3 3 3 0 Glutamate-cysteine ligase family 2(GCS2) Pkinase PF00069.25 KXS10165.1 - 3.7e-28 98.6 0.0 4.5e-28 98.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS10165.1 - 2.3e-13 50.0 0.0 3.4e-13 49.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXS10165.1 - 0.0022 17.3 0.0 0.0034 16.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KXS10165.1 - 0.043 13.2 0.0 0.065 12.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-CCHC_3 PF13917.6 KXS10167.1 - 7.7e-06 25.8 0.2 1.7e-05 24.6 0.2 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 KXS10167.1 - 0.0014 18.6 4.0 0.0024 17.9 4.0 1.4 1 0 0 1 1 1 1 Zinc knuckle BUD22 PF09073.10 KXS10167.1 - 0.88 8.8 42.9 1.3 8.3 42.9 1.3 1 0 0 1 1 1 0 BUD22 SRP-alpha_N PF04086.13 KXS10167.1 - 2.1 8.2 38.1 2.8 7.8 38.1 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal MFS_1 PF07690.16 KXS10168.1 - 1.2e-31 109.9 41.9 1.2e-31 109.9 41.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXS10168.1 - 1.8e-06 27.1 24.6 2.2e-05 23.5 24.8 2.6 1 1 0 1 1 1 1 Sugar (and other) transporter zf-MYND PF01753.18 KXS10169.1 - 4.5e-06 26.6 9.5 4.5e-06 26.6 9.5 3.6 2 1 0 2 2 2 1 MYND finger Glyco_transf_41 PF13844.6 KXS10170.1 - 6.3e-105 351.3 1.1 2.6e-50 171.2 0.0 4.2 4 1 0 5 5 5 3 Glycosyl transferase family 41 TPR_11 PF13414.6 KXS10170.1 - 1.8e-24 85.1 4.8 9.6e-07 28.4 0.2 6.7 5 1 2 7 7 7 5 TPR repeat TPR_1 PF00515.28 KXS10170.1 - 2.8e-23 80.7 10.1 2.4e-06 27.1 0.1 8.8 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_17 PF13431.6 KXS10170.1 - 1.1e-20 72.4 6.0 0.00039 20.6 0.1 7.5 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_2 PF07719.17 KXS10170.1 - 9.6e-17 59.7 11.5 0.00019 21.3 0.1 7.2 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 KXS10170.1 - 2.1e-16 58.7 1.9 0.0011 19.0 0.0 7.3 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 KXS10170.1 - 1.8e-15 56.3 12.1 0.0016 19.1 0.0 8.4 6 2 3 9 9 7 4 Tetratricopeptide repeat TPR_16 PF13432.6 KXS10170.1 - 1.7e-14 54.1 11.4 5.5e-10 39.7 0.1 5.3 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 KXS10170.1 - 7.4e-14 51.8 10.1 2.6e-06 27.6 0.4 6.2 4 4 1 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 KXS10170.1 - 1.7e-12 47.6 3.3 0.0012 19.3 0.2 4.3 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_7 PF13176.6 KXS10170.1 - 5.8e-12 44.7 5.2 0.00032 20.5 0.0 6.8 7 1 1 8 8 7 2 Tetratricopeptide repeat TPR_10 PF13374.6 KXS10170.1 - 5e-11 42.1 12.5 0.0011 18.7 0.1 6.8 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_9 PF13371.6 KXS10170.1 - 1.6e-05 24.9 1.0 0.00059 19.9 0.1 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 KXS10170.1 - 0.0015 19.0 6.9 11 6.9 0.1 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_15 PF13429.6 KXS10170.1 - 0.017 14.3 0.5 0.11 11.8 0.0 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat PPR PF01535.20 KXS10170.1 - 0.071 13.4 0.5 11 6.5 0.2 2.8 2 0 0 2 2 2 0 PPR repeat TPR_4 PF07721.14 KXS10170.1 - 1.4 9.7 10.7 15 6.5 0.0 5.1 5 0 0 5 5 3 0 Tetratricopeptide repeat Peptidase_S49 PF01343.18 KXS10171.1 - 2.1e-51 173.9 0.0 1.4e-36 125.8 0.0 3.0 3 0 0 3 3 3 2 Peptidase family S49 CLP_protease PF00574.23 KXS10171.1 - 0.019 14.9 0.1 0.43 10.4 0.0 2.6 3 0 0 3 3 3 0 Clp protease Ferritin PF00210.24 KXS10171.1 - 0.19 11.6 0.0 0.37 10.7 0.0 1.4 1 0 0 1 1 1 0 Ferritin-like domain Ion_trans PF00520.31 KXS10172.1 - 6.6e-05 22.2 8.4 8.9e-05 21.8 8.4 1.1 1 0 0 1 1 1 1 Ion transport protein DUF2207 PF09972.9 KXS10172.1 - 0.64 8.7 2.5 0.88 8.3 2.5 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Sgf11 PF08209.11 KXS10173.1 - 3.3e-10 39.4 0.1 3.3e-10 39.4 0.1 3.0 3 1 0 3 3 3 1 Sgf11 (transcriptional regulation protein) DZR PF12773.7 KXS10173.1 - 0.039 14.0 3.7 0.069 13.2 3.7 1.4 1 0 0 1 1 1 0 Double zinc ribbon Zn-ribbon_8 PF09723.10 KXS10173.1 - 0.64 10.2 5.3 9.3 6.5 5.3 2.3 1 1 0 1 1 1 0 Zinc ribbon domain SAMP PF05924.11 KXS10173.1 - 6.8 6.1 5.9 2.2 7.7 1.7 2.2 2 0 0 2 2 2 0 SAMP Motif PA28_alpha PF02251.18 KXS10174.1 - 0.016 15.3 0.2 3 8.0 0.3 2.6 2 0 0 2 2 2 0 Proteasome activator pa28 alpha subunit ApoLp-III PF07464.11 KXS10174.1 - 0.043 13.9 1.3 22 5.2 1.3 3.7 3 1 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) Ribosomal_L28e PF01778.17 KXS10175.1 - 2.2e-15 57.4 0.0 2.8e-15 57.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal L28e protein family PGA2 PF07543.12 KXS10176.1 - 9.5 6.2 14.6 22 5.0 14.6 1.6 1 0 0 1 1 1 0 Protein trafficking PGA2 BAR_3 PF16746.5 KXS10177.1 - 3.3e-47 161.2 0.2 5.3e-47 160.5 0.2 1.2 1 0 0 1 1 1 1 BAR domain of APPL family ArfGap PF01412.18 KXS10177.1 - 6.7e-37 126.1 0.0 1.8e-36 124.8 0.0 1.8 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PH PF00169.29 KXS10177.1 - 1e-09 38.8 0.0 2.1e-09 37.8 0.0 1.6 1 0 0 1 1 1 1 PH domain BAR PF03114.18 KXS10177.1 - 1.7e-09 37.7 1.2 3.9e-09 36.5 1.2 1.6 1 0 0 1 1 1 1 BAR domain Ank_5 PF13857.6 KXS10177.1 - 3.2e-08 33.7 0.5 3.4e-06 27.2 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXS10177.1 - 4.1e-07 30.5 0.0 1.6e-06 28.6 0.0 1.9 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXS10177.1 - 1.5e-05 25.0 0.0 0.0045 17.4 0.0 3.6 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 KXS10177.1 - 0.0006 20.1 0.1 0.026 15.0 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 KXS10177.1 - 0.00067 20.2 0.0 0.0077 16.8 0.0 2.4 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Vps5 PF09325.10 KXS10177.1 - 0.00095 18.8 0.6 0.0019 17.8 0.6 1.4 1 0 0 1 1 1 1 Vps5 C terminal like PH_17 PF18012.1 KXS10177.1 - 0.063 13.0 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 PH domain PPP4R2 PF09184.11 KXS10177.1 - 0.074 12.6 5.6 0.14 11.7 5.6 1.4 1 0 0 1 1 1 0 PPP4R2 FAM92 PF06730.11 KXS10177.1 - 0.14 11.5 0.6 0.24 10.8 0.6 1.2 1 0 0 1 1 1 0 FAM92 protein DUF3449 PF11931.8 KXS10177.1 - 1 9.1 4.3 2.2 8.0 4.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) NOA36 PF06524.12 KXS10177.1 - 1.6 8.0 11.0 2.6 7.3 11.0 1.2 1 0 0 1 1 1 0 NOA36 protein PBP1_TM PF14812.6 KXS10177.1 - 1.8 9.0 8.6 5.3 7.5 8.6 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4611 PF15387.6 KXS10177.1 - 2.7 8.2 16.6 1.2 9.4 13.4 2.1 2 0 0 2 2 1 0 Domain of unknown function (DUF4611) Nop14 PF04147.12 KXS10177.1 - 4.1 5.5 13.6 7.6 4.6 13.6 1.3 1 0 0 1 1 1 0 Nop14-like family Myc_N PF01056.18 KXS10177.1 - 5.1 6.9 10.3 0.23 11.3 3.1 2.1 2 0 0 2 2 2 0 Myc amino-terminal region EMP70 PF02990.16 KXS10178.1 - 2.3e-205 683.2 7.2 3.5e-205 682.6 7.2 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 F-box-like PF12937.7 KXS10180.1 - 6.8e-06 25.9 0.6 1e-05 25.3 0.6 1.2 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXS10180.1 - 0.00047 19.9 0.3 0.00072 19.4 0.3 1.3 1 0 0 1 1 1 1 F-box domain DUF3331 PF11811.8 KXS10180.1 - 0.01 15.7 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3331) Kinesin PF00225.23 KXS10182.1 - 3.3e-111 371.4 0.3 3.4e-109 364.8 0.0 2.7 2 0 0 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 KXS10182.1 - 3.2e-22 79.1 0.0 1.6e-21 76.8 0.0 2.3 2 0 0 2 2 2 1 Microtubule binding Exotox-A_cataly PF09009.10 KXS10182.1 - 0.023 14.4 0.1 0.11 12.2 0.1 2.2 1 0 0 1 1 1 0 Exotoxin A catalytic Peptidase_M74 PF03411.13 KXS10184.1 - 0.029 13.9 0.2 0.031 13.8 0.2 1.1 1 0 0 1 1 1 0 Penicillin-insensitive murein endopeptidase Fungal_trans PF04082.18 KXS10185.1 - 1.1e-11 44.3 0.3 4.1e-11 42.4 0.3 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXS10185.1 - 5.6e-06 26.4 15.4 1e-05 25.6 15.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AMP-binding PF00501.28 KXS10186.1 - 2.4e-59 201.0 0.0 3.9e-59 200.3 0.0 1.3 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXS10186.1 - 7e-17 62.2 0.1 1.4e-16 61.2 0.1 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AtuA PF07287.11 KXS10187.1 - 2.8e-113 378.2 0.0 3.6e-113 377.9 0.0 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA Sel1 PF08238.12 KXS10189.1 - 2.8e-36 123.1 18.9 3.7e-06 27.4 0.0 8.8 8 0 0 8 8 8 7 Sel1 repeat Pkinase_Tyr PF07714.17 KXS10189.1 - 1.2e-34 119.8 0.0 4.6e-31 108.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase LRR_6 PF13516.6 KXS10189.1 - 6e-34 113.2 51.7 0.00018 21.3 0.2 13.3 13 0 0 13 13 13 9 Leucine Rich repeat Pkinase PF00069.25 KXS10189.1 - 1.4e-24 86.9 0.0 5.1e-21 75.2 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain TPR_2 PF07719.17 KXS10189.1 - 6.4e-07 29.0 14.8 0.044 13.9 0.1 6.8 7 0 0 7 7 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 KXS10189.1 - 1.7e-06 28.2 7.5 0.22 11.8 0.2 4.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KXS10189.1 - 3.8e-06 27.3 2.6 1.4 9.4 0.1 5.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 KXS10189.1 - 0.00012 21.8 8.2 2.1 8.3 0.1 6.1 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.28 KXS10189.1 - 0.00017 21.3 14.4 0.58 10.1 0.0 6.2 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_8 PF13181.6 KXS10189.1 - 0.00059 19.8 5.5 6.4 7.3 0.1 5.9 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 KXS10189.1 - 0.0024 17.5 0.2 0.77 9.5 0.0 4.1 3 0 0 3 3 3 1 TPR repeat ANAPC3 PF12895.7 KXS10189.1 - 0.0024 18.1 1.0 3.3 8.0 0.0 4.0 5 0 0 5 5 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 KXS10189.1 - 0.0031 18.1 12.5 0.52 11.0 0.1 6.3 4 1 2 6 6 5 1 Tetratricopeptide repeat LRR_4 PF12799.7 KXS10189.1 - 0.0046 17.3 16.7 2.8 8.5 0.3 7.2 6 2 1 7 7 7 1 Leucine Rich repeats (2 copies) TPR_7 PF13176.6 KXS10189.1 - 0.0061 16.5 11.5 1.8 8.8 0.1 5.7 7 0 0 7 7 4 2 Tetratricopeptide repeat HOASN PF14515.6 KXS10189.1 - 0.015 15.6 16.1 0.46 10.9 0.3 7.0 3 2 4 8 8 8 0 Haem-oxygenase-associated N-terminal helices LRR_1 PF00560.33 KXS10189.1 - 0.083 13.5 9.2 30 5.7 0.1 7.4 11 0 0 11 11 6 0 Leucine Rich Repeat MIT PF04212.18 KXS10189.1 - 0.19 11.8 0.4 20 5.4 0.0 4.0 5 0 0 5 5 4 0 MIT (microtubule interacting and transport) domain DUF2202 PF09968.9 KXS10189.1 - 0.3 10.9 5.2 26 4.6 0.1 4.6 4 2 1 5 5 5 0 Uncharacterized protein domain (DUF2202) TPR_6 PF13174.6 KXS10189.1 - 0.8 10.5 7.4 47 4.9 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat Zn_Tnp_IS1595 PF12760.7 KXS10191.1 - 0.056 13.4 0.3 0.098 12.6 0.3 1.3 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Pellino PF04710.14 KXS10191.1 - 0.22 10.1 0.0 0.33 9.6 0.0 1.1 1 0 0 1 1 1 0 Pellino Sigma70_ner PF04546.13 KXS10192.1 - 3.2 7.6 7.3 6.7 6.5 7.0 1.7 2 0 0 2 2 2 0 Sigma-70, non-essential region Viral_helicase1 PF01443.18 KXS10194.1 - 0.031 14.0 0.4 0.034 13.9 0.4 1.1 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase FUSC PF04632.12 KXS10195.1 - 0.49 8.9 3.2 0.74 8.3 3.2 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family RBB1NT PF08169.11 KXS10196.1 - 0.028 14.5 0.0 0.042 14.0 0.0 1.4 1 0 0 1 1 1 0 RBB1NT (NUC162) domain F-box PF00646.33 KXS10196.1 - 0.045 13.6 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 F-box domain APH PF01636.23 KXS10197.1 - 0.0065 16.4 0.1 0.11 12.4 0.0 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family Xan_ur_permease PF00860.20 KXS10198.1 - 8.1e-75 251.9 42.3 1.1e-74 251.6 42.3 1.1 1 0 0 1 1 1 1 Permease family AIRS PF00586.24 KXS10198.1 - 1.8 9.3 5.3 24 5.7 0.7 2.9 2 0 0 2 2 2 0 AIR synthase related protein, N-terminal domain Aldolase_II PF00596.21 KXS10199.1 - 2.7e-48 164.4 0.0 3.3e-48 164.1 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain bZIP_1 PF00170.21 KXS10200.1 - 6.8e-08 32.5 10.6 1.3e-07 31.6 10.6 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 KXS10200.1 - 0.025 15.1 6.3 0.055 14.0 6.3 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor bZIP_2 PF07716.15 KXS10200.1 - 0.027 14.5 11.1 0.027 14.5 11.1 2.1 2 0 0 2 2 2 0 Basic region leucine zipper AA_permease_2 PF13520.6 KXS10201.1 - 5e-28 98.1 35.8 6.2e-28 97.8 35.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXS10201.1 - 0.00024 19.8 37.4 0.00052 18.7 37.4 1.6 1 1 0 1 1 1 1 Amino acid permease Amino_oxidase PF01593.24 KXS10203.1 - 1.5e-63 215.7 0.0 2e-63 215.3 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KXS10203.1 - 7.1e-17 61.4 0.3 1.8e-16 60.1 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KXS10203.1 - 2.5e-06 26.8 2.4 4.1e-06 26.1 2.4 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KXS10203.1 - 2.7e-05 23.1 0.9 3.8e-05 22.6 0.9 1.2 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.24 KXS10203.1 - 5.7e-05 22.9 5.2 0.00011 22.0 5.2 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KXS10203.1 - 8.1e-05 22.1 2.7 8.1e-05 22.1 2.7 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXS10203.1 - 0.00011 21.5 0.3 0.00024 20.4 0.3 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KXS10203.1 - 0.00018 20.9 1.7 0.00028 20.3 1.7 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KXS10203.1 - 0.0003 20.1 0.1 0.00056 19.2 0.1 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 KXS10203.1 - 0.0011 19.5 1.1 0.0025 18.3 1.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KXS10203.1 - 0.0015 17.7 1.1 0.051 12.6 0.6 2.3 2 0 0 2 2 2 1 Lycopene cyclase protein GIDA PF01134.22 KXS10203.1 - 0.0017 17.5 1.0 0.0025 17.0 1.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KXS10203.1 - 0.0028 17.0 1.3 0.0058 15.9 1.3 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KXS10203.1 - 0.0077 15.5 1.0 0.012 14.9 1.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain IlvN PF07991.12 KXS10203.1 - 0.021 14.4 0.1 0.035 13.7 0.1 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_9 PF13454.6 KXS10203.1 - 0.59 10.1 2.5 1.1 9.2 0.5 2.3 3 0 0 3 3 3 0 FAD-NAD(P)-binding zf-RING_2 PF13639.6 KXS10204.1 - 2.8e-07 30.8 3.0 4.4e-07 30.1 3.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KXS10204.1 - 1.3e-05 24.9 2.8 2.2e-05 24.2 2.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXS10204.1 - 1.5e-05 24.7 1.0 5.5e-05 22.9 1.2 1.8 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KXS10204.1 - 0.00068 19.3 1.6 0.00068 19.3 1.6 1.7 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_5 PF14634.6 KXS10204.1 - 0.0012 18.8 3.1 0.0019 18.1 3.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KXS10204.1 - 0.0018 18.1 3.3 0.0031 17.3 3.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KXS10204.1 - 0.0037 16.9 4.5 0.0068 16.0 4.5 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-rbx1 PF12678.7 KXS10204.1 - 0.0067 16.7 1.9 0.013 15.8 1.9 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KXS10204.1 - 0.016 15.2 0.1 0.05 13.6 0.1 1.8 1 1 1 2 2 2 0 RING-type zinc-finger Rad50_zn_hook PF04423.14 KXS10204.1 - 0.051 13.4 1.1 0.12 12.2 0.2 1.9 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-RING_2 PF13639.6 KXS10205.1 - 0.00022 21.5 2.0 0.00042 20.6 2.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KXS10205.1 - 0.00078 19.1 1.7 0.0024 17.6 0.5 2.2 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KXS10205.1 - 0.022 14.6 1.5 0.066 13.1 1.8 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXS10205.1 - 0.076 12.9 1.1 0.13 12.1 1.1 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C2H2 PF00096.26 KXS10205.1 - 0.13 12.7 0.2 0.27 11.8 0.2 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type Prok-RING_1 PF14446.6 KXS10205.1 - 0.6 10.1 5.3 0.24 11.4 1.8 1.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 PHD PF00628.29 KXS10205.1 - 1.4 8.9 3.5 7.6 6.5 3.6 2.1 1 1 0 1 1 1 0 PHD-finger SMC_ScpA PF02616.14 KXS10205.1 - 1.9 8.3 4.8 2.6 7.9 4.8 1.2 1 0 0 1 1 1 0 Segregation and condensation protein ScpA zf-MYND PF01753.18 KXS10206.1 - 2.7e-07 30.5 2.1 3.5e-07 30.2 2.1 1.2 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KXS10206.1 - 7.7e-05 22.9 2.0 0.00016 21.9 2.0 1.5 1 1 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding PPR_3 PF13812.6 KXS10207.1 - 1.3e-08 34.8 0.0 0.00051 20.1 0.0 2.9 2 1 0 2 2 2 2 Pentatricopeptide repeat domain PPR_2 PF13041.6 KXS10207.1 - 4.5e-05 23.5 0.0 0.00081 19.5 0.0 2.3 2 1 0 2 2 2 1 PPR repeat family PPR_long PF17177.4 KXS10207.1 - 0.0059 16.0 0.0 0.0079 15.6 0.0 1.2 1 0 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP TPR_19 PF14559.6 KXS10207.1 - 0.11 13.0 0.0 0.18 12.3 0.0 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat bacHORMA_2 PF18173.1 KXS10207.1 - 0.14 12.0 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 Bacterial HORMA domain 2 NGP1NT PF08153.12 KXS10208.1 - 3.7e-44 150.0 0.0 3.7e-44 150.0 0.0 1.7 2 0 0 2 2 2 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 KXS10208.1 - 5e-18 65.2 0.2 9.1e-14 51.5 0.0 3.4 3 0 0 3 3 3 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KXS10208.1 - 8.8e-06 25.7 0.0 0.00039 20.4 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase FeoB_N PF02421.18 KXS10208.1 - 0.00021 20.9 0.0 0.00047 19.7 0.0 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B Coilin_N PF15862.5 KXS10208.1 - 0.00057 19.7 0.0 0.011 15.5 0.0 2.7 2 1 0 2 2 2 1 Coilin N-terminus GTP_EFTU PF00009.27 KXS10208.1 - 0.0038 16.8 0.0 2.3 7.7 0.0 3.5 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain Arf PF00025.21 KXS10208.1 - 0.018 14.5 0.1 0.081 12.4 0.0 1.9 2 0 0 2 2 2 0 ADP-ribosylation factor family Roc PF08477.13 KXS10208.1 - 0.087 13.0 0.0 13 6.0 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 KXS10208.1 - 0.18 11.9 2.8 0.53 10.3 0.0 3.0 3 1 1 4 4 4 0 Dynamin family SART-1 PF03343.13 KXS10209.1 - 1.1e-128 430.6 48.1 1.3e-128 430.3 48.1 1.0 1 0 0 1 1 1 1 SART-1 family DUF4241 PF14025.6 KXS10210.1 - 0.096 13.0 0.1 0.25 11.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4241) Aldedh PF00171.22 KXS10211.1 - 1.5e-120 402.8 0.0 7e-120 400.6 0.0 1.7 1 1 0 1 1 1 1 Aldehyde dehydrogenase family CBM_1 PF00734.18 KXS10212.1 - 7.3e-26 89.8 24.9 1.1e-12 47.7 6.6 3.5 2 0 0 2 2 2 2 Fungal cellulose binding domain DUF1993 PF09351.10 KXS10212.1 - 0.52 10.4 2.5 1.1 9.4 2.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1993) VWA_2 PF13519.6 KXS10213.1 - 1.7e-10 41.5 0.2 4.3e-10 40.2 0.2 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 KXS10213.1 - 2.5e-09 37.7 0.0 4.9e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 KXS10213.1 - 6.4e-06 26.2 0.1 1.5e-05 25.0 0.1 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 KXS10213.1 - 0.001 18.5 0.4 0.0023 17.4 0.4 1.6 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein Thymopoietin PF08198.11 KXS10214.1 - 0.00019 21.0 0.2 0.00036 20.1 0.2 1.4 1 0 0 1 1 1 1 Thymopoietin protein LAGLIDADG_3 PF14528.6 KXS10215.1 - 2.6e-07 30.8 0.1 0.0026 18.0 0.1 2.5 2 0 0 2 2 2 2 LAGLIDADG-like domain LAGLIDADG_1 PF00961.19 KXS10215.1 - 0.00028 21.8 2.0 0.014 16.3 0.1 3.4 2 1 0 2 2 2 1 LAGLIDADG endonuclease Hom_end PF05204.14 KXS10215.1 - 0.097 12.8 0.0 31 4.8 0.0 3.1 2 1 1 3 3 3 0 Homing endonuclease D5_N PF08706.11 KXS10216.1 - 3.2e-12 47.0 0.0 9.7e-12 45.4 0.0 1.7 1 1 0 1 1 1 1 D5 N terminal like D5_N PF08706.11 KXS10217.1 - 1.5e-09 38.2 0.0 2.9e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 D5 N terminal like Herpes_UL52 PF03121.15 KXS10217.1 - 0.00028 20.7 0.6 0.00056 19.8 0.6 1.4 1 0 0 1 1 1 1 Herpesviridae UL52/UL70 DNA primase Prim-Pol PF09250.11 KXS10217.1 - 0.0028 18.1 0.0 0.0066 16.8 0.0 1.6 1 0 0 1 1 1 1 Bifunctional DNA primase/polymerase, N-terminal RNA_POL_M_15KD PF02150.16 KXS10217.1 - 0.0046 16.8 0.4 0.0091 15.8 0.4 1.4 1 0 0 1 1 1 1 RNA polymerases M/15 Kd subunit Nop25 PF09805.9 KXS10220.1 - 8.6 6.8 15.3 17 5.9 15.3 1.4 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) Pkinase_Tyr PF07714.17 KXS10221.1 - 4.8e-28 98.2 0.0 6.8e-28 97.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXS10221.1 - 3.2e-26 92.3 0.0 4.8e-26 91.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KXS10221.1 - 0.00013 20.9 0.0 0.00026 19.9 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 KXS10221.1 - 0.011 15.7 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family NYN PF01936.18 KXS10221.1 - 0.13 12.8 0.0 0.21 12.0 0.0 1.5 1 0 0 1 1 1 0 NYN domain Aldo_ket_red PF00248.21 KXS10222.1 - 9.4e-25 87.4 0.0 1.1e-24 87.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF3860 PF12976.7 KXS10222.1 - 0.05 13.6 0.0 0.08 13.0 0.0 1.3 1 1 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3860) tRNA_edit PF04073.15 KXS10222.1 - 0.14 12.3 0.0 0.23 11.6 0.0 1.3 1 0 0 1 1 1 0 Aminoacyl-tRNA editing domain Aldo_ket_red PF00248.21 KXS10223.1 - 2.4e-74 250.2 0.0 2.7e-74 250.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family ATP-synt_F6 PF05511.11 KXS10223.1 - 0.089 13.2 0.0 0.32 11.4 0.0 1.9 2 0 0 2 2 2 0 Mitochondrial ATP synthase coupling factor 6 Aldo_ket_red PF00248.21 KXS10224.1 - 2.7e-73 246.7 0.0 3.2e-73 246.5 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family WW PF00397.26 KXS10225.1 - 0.0024 17.9 10.2 0.011 15.8 10.2 2.1 1 1 0 1 1 1 1 WW domain SH3_1 PF00018.28 KXS10226.1 - 2e-08 33.7 0.0 3.3e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KXS10226.1 - 2.7e-08 33.5 0.0 5.2e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KXS10226.1 - 0.005 16.5 0.0 0.0095 15.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Phage_Coat_B PF05356.11 KXS10226.1 - 0.22 11.5 0.1 0.22 11.5 0.1 3.2 4 0 0 4 4 4 0 Phage Coat protein B Bacteriocin_IIc PF10439.9 KXS10226.1 - 0.38 10.9 5.6 1.2 9.3 5.6 1.9 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide SH3_1 PF00018.28 KXS10227.1 - 2.6e-06 26.9 0.0 4.4e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KXS10227.1 - 0.00014 21.7 0.0 0.00042 20.1 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain Sina PF03145.16 KXS10228.1 - 8e-05 22.7 1.6 0.00013 22.0 1.6 1.3 1 0 0 1 1 1 1 Seven in absentia protein family zf-CCHC PF00098.23 KXS10230.1 - 2.3e-06 27.4 1.1 2.3e-06 27.4 1.1 2.2 2 0 0 2 2 2 1 Zinc knuckle Ank_2 PF12796.7 KXS10232.1 - 5.6e-12 46.1 1.3 1.6e-10 41.4 0.1 1.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXS10232.1 - 5.1e-07 30.1 0.5 0.0073 16.9 0.3 2.7 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXS10232.1 - 6.2e-07 29.3 0.9 0.64 10.8 0.0 3.9 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 KXS10232.1 - 8.7e-05 22.8 2.0 2.8 8.5 0.1 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 KXS10232.1 - 0.00041 20.6 2.0 0.025 14.9 0.1 3.4 1 1 3 4 4 4 1 Ankyrin repeats (many copies) FoP_duplication PF13865.6 KXS10233.1 - 1.2 9.7 22.4 0.86 10.2 4.7 2.4 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 VWA PF00092.28 KXS10234.1 - 1.5e-10 41.6 0.0 4.7e-10 40.0 0.0 1.7 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_3 PF13768.6 KXS10234.1 - 2.5e-08 34.0 0.0 5.6e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KXS10234.1 - 1.3e-06 29.0 0.2 4.6e-06 27.2 0.0 1.9 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 KXS10234.1 - 0.019 14.3 0.3 0.071 12.5 0.1 1.9 2 1 0 2 2 2 0 VWA domain containing CoxE-like protein GST_N_2 PF13409.6 KXS10235.1 - 2.8e-08 33.9 0.0 6.4e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KXS10235.1 - 3.3e-07 30.6 0.0 1.1e-06 29.0 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KXS10235.1 - 9.2e-07 28.8 0.1 3.4e-06 27.0 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KXS10235.1 - 3.1e-05 24.1 0.0 7.1e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KXS10235.1 - 5.7e-05 23.3 0.0 0.0022 18.2 0.0 2.5 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain CTV_P6 PF06706.11 KXS10238.1 - 0.019 14.7 0.5 0.031 14.0 0.5 1.3 1 0 0 1 1 1 0 Citrus tristeza virus 6-kDa protein zf-RING_2 PF13639.6 KXS10239.1 - 1.5e-10 41.2 3.6 1.5e-10 41.2 3.6 1.7 2 0 0 2 2 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KXS10239.1 - 4.2e-08 33.1 2.2 2.7e-07 30.5 0.4 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KXS10239.1 - 4.9e-08 32.7 2.8 9.5e-08 31.8 2.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KXS10239.1 - 1.2e-07 31.3 1.5 1.2e-07 31.3 1.5 1.8 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 KXS10239.1 - 8.2e-07 28.8 0.8 1.5e-06 27.9 0.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KXS10239.1 - 1.9e-05 24.9 8.0 0.00011 22.4 8.2 2.1 1 1 1 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 KXS10239.1 - 8.8e-05 22.3 1.2 0.00016 21.5 1.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXS10239.1 - 0.00014 21.8 0.6 0.00014 21.8 0.6 1.7 2 0 0 2 2 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KXS10239.1 - 0.00053 20.1 1.0 0.0015 18.6 1.1 1.8 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 KXS10239.1 - 0.00083 19.4 3.3 0.0026 17.8 3.3 1.8 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 KXS10239.1 - 0.0014 18.2 2.6 0.0027 17.3 2.6 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_9 PF13901.6 KXS10239.1 - 0.094 12.7 0.5 0.14 12.1 0.5 1.2 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon zf-RING_4 PF14570.6 KXS10239.1 - 0.15 11.9 1.2 0.29 11.0 1.2 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 KXS10239.1 - 0.22 11.4 9.3 0.13 12.2 3.8 2.7 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 PHD PF00628.29 KXS10239.1 - 0.36 10.7 1.8 1.5 8.7 1.7 2.0 1 1 1 2 2 2 0 PHD-finger zf-C3H2C3 PF17122.5 KXS10239.1 - 0.37 10.9 8.5 0.11 12.5 1.3 2.6 2 0 0 2 2 2 0 Zinc-finger zf-Nse PF11789.8 KXS10239.1 - 0.38 10.6 1.8 0.95 9.3 1.8 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit FANCL_C PF11793.8 KXS10239.1 - 0.65 10.2 3.0 5.3 7.3 3.0 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain Prok-RING_1 PF14446.6 KXS10239.1 - 1.2 9.2 4.7 8.8 6.3 0.4 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Rad50_zn_hook PF04423.14 KXS10239.1 - 4 7.4 5.6 0.29 11.0 0.5 1.6 2 0 0 2 2 1 0 Rad50 zinc hook motif zf-Di19 PF05605.12 KXS10239.1 - 4.1 7.8 5.7 22 5.4 0.8 2.5 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-MIZ PF02891.20 KXS10239.1 - 9.3 6.1 7.2 76 3.2 7.2 2.3 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger zf-RING_2 PF13639.6 KXS10240.1 - 2.4e-11 43.8 4.0 3.8e-11 43.1 4.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KXS10240.1 - 1.1e-08 34.7 1.6 2.3e-08 33.6 1.6 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 KXS10240.1 - 1.2e-08 34.8 2.5 6e-08 32.6 0.5 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KXS10240.1 - 1.8e-08 34.0 3.8 3e-08 33.4 3.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXS10240.1 - 1.3e-07 31.4 1.0 1.9e-07 30.8 1.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KXS10240.1 - 9.3e-06 25.4 1.4 1.4e-05 24.8 1.4 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KXS10240.1 - 2.4e-05 24.5 7.0 0.00011 22.4 7.1 2.0 1 1 1 2 2 2 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KXS10240.1 - 2.5e-05 24.1 0.5 4e-05 23.5 0.5 1.3 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KXS10240.1 - 0.00064 19.5 4.0 0.0061 16.4 3.9 2.1 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KXS10240.1 - 0.00083 19.5 1.4 0.0019 18.3 1.5 1.6 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 KXS10240.1 - 0.001 19.1 2.6 0.0036 17.3 2.7 1.9 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 KXS10240.1 - 0.0028 17.2 2.5 0.0047 16.5 2.5 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 KXS10240.1 - 0.081 12.7 1.3 0.12 12.2 1.3 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Di19 PF05605.12 KXS10240.1 - 0.23 11.8 1.0 9.5 6.6 0.0 2.2 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C3H2C3 PF17122.5 KXS10240.1 - 0.52 10.4 5.2 1.6 8.8 5.1 1.9 1 1 0 1 1 1 0 Zinc-finger Rad50_zn_hook PF04423.14 KXS10240.1 - 0.81 9.6 3.8 0.2 11.5 0.4 1.6 2 0 0 2 2 2 0 Rad50 zinc hook motif FANCL_C PF11793.8 KXS10240.1 - 1.7 8.9 3.2 12 6.2 3.2 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain MFS_1 PF07690.16 KXS10242.1 - 1.6e-54 185.2 67.1 1.1e-41 142.9 39.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KXS10242.1 - 3.7e-15 55.7 22.4 5.2e-09 35.4 6.0 3.2 1 1 2 3 3 3 3 MFS_1 like family Sugar_tr PF00083.24 KXS10242.1 - 8.1e-12 44.7 28.7 5.4e-06 25.5 8.7 2.9 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_4 PF06779.14 KXS10242.1 - 5.8e-09 35.7 31.9 1.4e-06 27.9 12.6 3.1 2 1 1 3 3 3 3 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 KXS10242.1 - 1.7e-05 23.3 11.9 3.5e-05 22.3 7.6 2.7 1 1 1 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family MFS_3 PF05977.13 KXS10242.1 - 0.096 11.1 27.9 0.25 9.7 11.3 2.1 1 1 0 2 2 2 0 Transmembrane secretion effector MccV PF17508.2 KXS10242.1 - 0.21 12.1 2.3 6.6 7.3 0.2 3.1 2 0 0 2 2 2 0 Microcin V bacteriocin MFS_1 PF07690.16 KXS10243.1 - 2.4e-34 118.8 6.8 2.7e-34 118.6 6.8 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 KXS10243.1 - 4.7e-07 28.7 6.7 6.1e-07 28.4 6.7 1.1 1 0 0 1 1 1 1 MFS/sugar transport protein MFS_1_like PF12832.7 KXS10243.1 - 1.2e-05 24.4 6.5 0.0044 15.9 5.7 2.1 1 1 1 2 2 2 2 MFS_1 like family Sugar_tr PF00083.24 KXS10243.1 - 2.2e-05 23.5 10.0 3e-05 23.1 2.3 1.9 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_4 PF06779.14 KXS10243.1 - 0.00037 19.9 8.6 0.0011 18.4 6.7 1.8 1 1 1 2 2 2 2 Uncharacterised MFS-type transporter YbfB TRI12 PF06609.13 KXS10243.1 - 0.0055 15.2 1.8 0.0064 15.0 1.8 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 KXS10243.1 - 0.0089 14.5 3.8 0.011 14.2 3.8 1.1 1 0 0 1 1 1 1 Transmembrane secretion effector OATP PF03137.20 KXS10243.1 - 0.021 13.1 8.6 0.012 14.0 2.4 2.1 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF697 PF05128.12 KXS10243.1 - 0.34 10.6 3.4 0.64 9.7 3.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF697) CPP1-like PF11833.8 KXS10243.1 - 1.1 8.8 5.1 4.4 6.9 5.1 1.9 1 1 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like FAD_binding_3 PF01494.19 KXS10244.1 - 2.9e-23 82.7 0.0 4.8e-23 82.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.24 KXS10244.1 - 1.5e-07 31.1 0.3 0.0027 17.1 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase DAO PF01266.24 KXS10244.1 - 1.9e-06 27.7 1.1 0.0028 17.3 0.4 2.1 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KXS10244.1 - 1.7e-05 24.3 0.1 0.012 14.9 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXS10244.1 - 8e-05 22.8 0.1 0.00019 21.6 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 KXS10244.1 - 0.00011 21.3 0.3 0.016 14.0 0.1 2.1 1 1 1 2 2 2 2 Tryptophan halogenase Pyr_redox_2 PF07992.14 KXS10244.1 - 0.03 13.5 1.3 1.6 7.9 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXS10244.1 - 0.21 10.8 1.1 0.38 10.0 0.1 1.8 2 0 0 2 2 2 0 Thi4 family Pyr_redox PF00070.27 KXS10244.1 - 4.3 8.0 6.3 13 6.5 0.1 3.5 4 0 0 4 4 4 0 Pyridine nucleotide-disulphide oxidoreductase zf-HIT PF04438.16 KXS10245.1 - 4.1e-07 29.7 10.9 6.4e-07 29.1 10.9 1.3 1 0 0 1 1 1 1 HIT zinc finger MFS_1 PF07690.16 KXS10247.1 - 1.7e-28 99.6 44.5 2.3e-26 92.6 32.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Cytochrom_B558a PF05038.13 KXS10247.1 - 0.036 13.7 1.1 0.099 12.2 1.1 1.8 1 0 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit Methyltranf_PUA PF13636.6 KXS10247.1 - 0.25 11.3 0.9 1.6 8.8 0.1 2.6 3 0 0 3 3 3 0 RNA-binding PUA-like domain of methyltransferase RsmF DDE_Tnp_4 PF13359.6 KXS10250.1 - 4.6e-10 39.4 0.0 5.8e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease CHCH PF06747.13 KXS10250.1 - 0.034 14.3 0.6 1.4 9.1 0.0 2.5 2 0 0 2 2 2 0 CHCH domain Lipase_GDSL PF00657.22 KXS10251.1 - 1.3e-05 25.3 0.0 3.4e-05 23.9 0.0 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Ank_2 PF12796.7 KXS10253.1 - 5.9e-21 74.9 0.2 1.9e-10 41.2 0.2 2.8 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXS10253.1 - 1.3e-18 67.1 0.0 2e-09 37.8 0.1 5.0 4 2 1 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXS10253.1 - 2e-16 58.4 0.2 0.027 15.0 0.0 6.5 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.6 KXS10253.1 - 6.4e-10 39.1 0.8 0.0052 17.1 0.0 4.7 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 KXS10253.1 - 2.6e-09 37.1 0.4 0.28 11.7 0.1 5.9 7 0 0 7 7 7 2 Ankyrin repeat gag-asp_proteas PF13975.6 KXS10257.1 - 0.0014 19.2 0.0 0.0023 18.5 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 KXS10257.1 - 0.13 12.1 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease Ank_2 PF12796.7 KXS10261.1 - 2.2e-32 111.5 5.3 8.4e-10 39.1 0.0 5.3 2 1 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXS10261.1 - 4.8e-27 91.0 5.4 0.037 14.6 0.1 9.0 9 0 0 9 9 9 7 Ankyrin repeat Ank_4 PF13637.6 KXS10261.1 - 2.2e-26 91.8 5.5 3.5e-07 30.7 0.2 7.1 3 2 5 8 8 8 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXS10261.1 - 2e-15 56.7 10.0 0.022 15.1 0.1 8.0 3 2 5 8 8 8 5 Ankyrin repeats (many copies) Ank PF00023.30 KXS10261.1 - 9.7e-12 44.8 8.6 1.4 9.5 0.1 9.0 8 2 1 9 9 9 4 Ankyrin repeat Maf_N PF08383.11 KXS10261.1 - 6.1 6.7 5.2 78 3.2 0.0 3.5 3 1 0 3 3 3 0 Maf N-terminal region Beta-lactamase2 PF13354.6 KXS10262.1 - 3.3e-23 82.4 0.0 5.1e-23 81.7 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase enzyme family Beta-lactamase PF00144.24 KXS10262.1 - 4.2e-05 22.9 0.1 8.3e-05 22.0 0.0 1.6 2 0 0 2 2 2 1 Beta-lactamase CBS PF00571.28 KXS10263.1 - 4.4e-20 71.9 1.7 2.9e-05 24.4 0.0 4.3 4 1 0 4 4 4 3 CBS domain Glyco_transf_15 PF01793.16 KXS10264.1 - 2e-106 355.9 6.0 2.2e-106 355.8 6.0 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase DUF3405 PF11885.8 KXS10264.1 - 0.1 11.2 2.9 0.1 11.2 1.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3405) EMP24_GP25L PF01105.24 KXS10265.1 - 1.5e-42 145.6 0.6 1.7e-42 145.4 0.6 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD BCA_ABC_TP_C PF12399.8 KXS10266.1 - 0.061 13.3 1.6 0.1 12.6 0.2 1.9 2 0 0 2 2 2 0 Branched-chain amino acid ATP-binding cassette transporter DUF2075 PF09848.9 KXS10267.1 - 0.00037 19.8 0.1 0.00048 19.5 0.1 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Retrotran_gag_2 PF14223.6 KXS10267.1 - 0.00075 19.2 0.1 0.0011 18.6 0.1 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Histone PF00125.24 KXS10268.1 - 3.1e-23 82.6 0.2 8.6e-23 81.1 0.2 1.6 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 KXS10268.1 - 0.00045 20.3 0.1 0.00062 19.9 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Bromo_TP PF07524.13 KXS10268.1 - 0.022 14.7 0.1 0.034 14.1 0.1 1.4 1 0 0 1 1 1 0 Bromodomain associated CBFD_NFYB_HMF PF00808.23 KXS10268.1 - 0.078 13.3 0.1 0.13 12.6 0.1 1.3 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Dimer_Tnp_hAT PF05699.14 KXS10269.1 - 1.9e-09 37.2 0.0 7.1e-09 35.3 0.0 2.0 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region Condensation PF00668.20 KXS10272.1 - 2.9e-26 92.2 0.0 5.7e-26 91.2 0.0 1.4 1 1 0 1 1 1 1 Condensation domain Sel1 PF08238.12 KXS10275.1 - 5.3e-39 131.8 10.8 4.1e-08 33.6 0.2 5.4 5 0 0 5 5 5 5 Sel1 repeat TPR_10 PF13374.6 KXS10275.1 - 9.2 6.3 6.8 7.2 6.6 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Pkinase_Tyr PF07714.17 KXS10276.1 - 0.069 12.4 0.1 0.095 12.0 0.1 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase APH PF01636.23 KXS10277.1 - 5.2e-10 39.7 0.0 1.3e-09 38.4 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 KXS10277.1 - 8.2e-10 38.5 0.0 9.9e-07 28.4 0.0 2.2 2 0 0 2 2 2 2 Ecdysteroid kinase DUF1679 PF07914.11 KXS10277.1 - 0.084 11.7 0.0 0.17 10.7 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) APH PF01636.23 KXS10278.1 - 3.7e-30 105.6 0.2 5e-30 105.2 0.2 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 KXS10278.1 - 0.021 14.1 0.0 0.047 13.0 0.0 1.5 1 0 0 1 1 1 0 Ecdysteroid kinase SH3_9 PF14604.6 KXS10279.1 - 2e-09 37.2 0.0 4.2e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXS10279.1 - 3.1e-06 26.7 0.0 5.8e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 SH3 domain Podoplanin PF05808.11 KXS10279.1 - 0.022 14.9 4.6 0.041 14.0 4.6 1.4 1 0 0 1 1 1 0 Podoplanin Pyocin_S PF06958.12 KXS10279.1 - 0.1 13.2 2.1 0.22 12.0 2.1 1.5 1 0 0 1 1 1 0 S-type Pyocin SH3_2 PF07653.17 KXS10279.1 - 0.13 11.9 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain SPX PF03105.19 KXS10279.1 - 0.2 11.5 6.2 0.29 11.0 6.2 1.2 1 0 0 1 1 1 0 SPX domain Apt1 PF10351.9 KXS10279.1 - 0.77 8.5 6.1 1.1 8.1 6.1 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 KXS10279.1 - 5.1 5.5 11.7 7.1 5.0 11.7 1.1 1 0 0 1 1 1 0 Macoilin family F-box PF00646.33 KXS10280.1 - 0.25 11.3 0.9 1.4 8.9 0.1 2.5 2 0 0 2 2 2 0 F-box domain EB PF01683.18 KXS10283.1 - 0.00018 21.7 0.9 0.00045 20.5 0.9 1.7 1 0 0 1 1 1 1 EB module FhuF_C PF11575.8 KXS10283.1 - 0.1 12.5 12.3 0.23 11.4 2.7 3.1 3 0 0 3 3 3 0 FhuF 2Fe-2S C-terminal domain DUF390 PF04094.14 KXS10283.1 - 0.75 8.0 5.6 1.9 6.7 5.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF390) zf-MYND PF01753.18 KXS10286.1 - 1.3e-10 41.2 9.2 1.3e-10 41.2 9.2 1.5 2 0 0 2 2 2 1 MYND finger zf-C6H2 PF15801.5 KXS10286.1 - 0.0013 19.0 7.1 0.0026 18.0 7.1 1.5 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding Ecl1 PF12855.7 KXS10286.1 - 0.03 15.5 0.3 0.032 15.4 0.3 1.2 1 0 0 1 1 1 0 ECL1/2/3 zinc binding proteins Phenol_monoox PF04663.12 KXS10286.1 - 0.12 12.5 0.0 0.17 12.0 0.0 1.2 1 0 0 1 1 1 0 Phenol hydroxylase conserved region MFS_1 PF07690.16 KXS10288.1 - 1.2e-25 90.2 52.8 5.7e-16 58.4 28.2 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Gemini_mov PF01708.16 KXS10288.1 - 0.3 10.9 1.2 0.67 9.8 0.1 2.1 2 0 0 2 2 2 0 Geminivirus putative movement protein BTB PF00651.31 KXS10289.1 - 0.015 15.5 0.0 0.038 14.2 0.0 1.7 1 1 0 1 1 1 0 BTB/POZ domain DUF2153 PF09921.9 KXS10289.1 - 0.075 12.8 0.2 0.12 12.2 0.2 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2153) BTB PF00651.31 KXS10290.1 - 7.4e-10 39.0 0.0 1.6e-09 37.9 0.0 1.6 2 0 0 2 2 2 1 BTB/POZ domain Beta-lactamase2 PF13354.6 KXS10291.1 - 0.013 15.1 0.0 0.028 14.0 0.0 1.6 1 0 0 1 1 1 0 Beta-lactamase enzyme family AF-4 PF05110.13 KXS10292.1 - 8.5 4.3 6.4 11 3.9 6.4 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Fungal_trans PF04082.18 KXS10293.1 - 1.6e-06 27.3 0.4 3.5e-06 26.2 0.3 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Glyoxalase_6 PF18029.1 KXS10294.1 - 0.00011 23.0 0.0 0.00016 22.4 0.0 1.4 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.25 KXS10294.1 - 0.0012 19.0 0.0 0.002 18.3 0.0 1.4 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase PF00903.25 KXS10295.1 - 0.00073 19.7 0.0 0.0029 17.8 0.0 1.9 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 KXS10295.1 - 0.016 16.0 0.0 0.021 15.6 0.0 1.2 1 0 0 1 1 1 0 Glyoxalase-like domain Ceramidase PF05875.12 KXS10296.1 - 2.1e-61 207.7 9.9 2.6e-61 207.3 9.9 1.0 1 0 0 1 1 1 1 Ceramidase UPF0121 PF03661.13 KXS10297.1 - 3.8e-35 121.4 9.8 5e-35 121.0 9.8 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) Med16 PF11635.8 KXS10298.1 - 0.089 10.7 2.1 0.18 9.7 2.0 1.7 1 1 0 1 1 1 0 Mediator complex subunit 16 PhoLip_ATPase_C PF16212.5 KXS10299.1 - 1.9e-57 194.9 15.6 1.9e-57 194.9 15.6 2.3 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KXS10299.1 - 2.6e-15 55.9 0.2 7.4e-15 54.4 0.2 1.7 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KXS10299.1 - 6e-12 46.3 0.3 2.2e-06 28.1 0.2 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KXS10299.1 - 1.7e-10 40.9 0.0 3e-09 36.8 0.0 2.3 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 KXS10299.1 - 5.6e-07 29.2 0.0 5.6e-07 29.2 0.0 3.5 3 1 0 3 3 3 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KXS10299.1 - 0.0031 17.3 0.7 0.0068 16.2 0.0 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase LRR_4 PF12799.7 KXS10300.1 - 0.0014 18.9 3.0 0.0042 17.5 3.0 1.8 1 0 0 1 1 1 1 Leucine Rich repeats (2 copies) Podoplanin PF05808.11 KXS10300.1 - 0.051 13.7 0.1 0.051 13.7 0.1 1.9 2 0 0 2 2 2 0 Podoplanin LRR_8 PF13855.6 KXS10300.1 - 0.078 12.8 4.2 0.21 11.4 4.2 1.7 1 1 0 1 1 1 0 Leucine rich repeat SH3_1 PF00018.28 KXS10300.1 - 0.2 11.3 0.0 0.4 10.3 0.0 1.4 1 0 0 1 1 1 0 SH3 domain SKG6 PF08693.10 KXS10300.1 - 0.36 10.3 4.9 0.99 8.9 4.9 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain TrbC PF04956.13 KXS10300.1 - 0.95 9.7 6.2 3.9 7.8 0.0 2.7 2 0 0 2 2 2 0 TrbC/VIRB2 family Acetyltransf_1 PF00583.25 KXS10301.1 - 8.6e-11 42.1 0.0 1.7e-09 38.0 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXS10301.1 - 1.7e-07 31.6 0.0 3.8e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KXS10301.1 - 4.3e-06 26.7 0.0 7.8e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXS10301.1 - 2.8e-05 24.0 0.0 4.9e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_13 PF13880.6 KXS10301.1 - 0.076 13.0 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Acetyltransf_8 PF13523.6 KXS10301.1 - 0.079 12.6 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KXS10301.1 - 0.13 13.0 0.0 0.24 12.1 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KXS10301.1 - 0.13 12.3 0.0 1.1 9.4 0.0 2.2 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain F-box PF00646.33 KXS10304.1 - 0.072 13.0 0.1 0.15 12.0 0.1 1.5 1 0 0 1 1 1 0 F-box domain CtnDOT_TraJ PF07863.11 KXS10305.1 - 0.14 12.8 1.0 0.32 11.7 0.0 2.2 2 1 0 2 2 2 0 Homologues of TraJ from Bacteroides conjugative transposon zf-H2C2_2 PF13465.6 KXS10306.1 - 1.1e-10 41.4 2.3 9.7e-08 32.1 0.2 2.3 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KXS10306.1 - 8.6e-06 26.2 4.7 0.0002 21.9 1.7 2.2 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2 PF00096.26 KXS10306.1 - 8.8e-06 25.9 6.4 3.7e-05 23.9 2.9 2.1 2 0 0 2 2 2 1 Zinc finger, C2H2 type DZR PF12773.7 KXS10306.1 - 0.0013 18.7 0.2 0.0018 18.2 0.2 1.2 1 0 0 1 1 1 1 Double zinc ribbon zf_UBZ PF18439.1 KXS10306.1 - 0.002 17.7 0.5 0.18 11.4 0.0 2.4 2 0 0 2 2 2 1 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 KXS10306.1 - 0.0035 17.4 1.5 0.18 11.9 1.5 2.1 1 1 1 2 2 2 2 Zinc ribbon domain ADK_lid PF05191.14 KXS10306.1 - 0.0046 16.9 0.1 0.0099 15.8 0.1 1.6 1 1 0 1 1 1 1 Adenylate kinase, active site lid Zn_ribbon_recom PF13408.6 KXS10306.1 - 0.0055 17.2 1.1 0.59 10.7 0.1 2.1 2 0 0 2 2 2 1 Recombinase zinc beta ribbon domain zinc_ribbon_9 PF14369.6 KXS10306.1 - 0.0056 16.9 0.6 3.4 8.0 0.1 2.2 2 0 0 2 2 2 2 zinc-ribbon GATA PF00320.27 KXS10306.1 - 0.0091 15.6 0.7 0.82 9.3 0.0 2.2 2 0 0 2 2 2 1 GATA zinc finger zf-RING_7 PF02591.15 KXS10306.1 - 0.01 16.0 0.4 3.7 7.8 0.0 2.2 2 0 0 2 2 2 1 C4-type zinc ribbon domain PhnA_Zn_Ribbon PF08274.12 KXS10306.1 - 0.013 15.4 0.3 1.7 8.7 0.1 2.1 2 0 0 2 2 2 0 PhnA Zinc-Ribbon zf-ribbon_3 PF13248.6 KXS10306.1 - 0.015 14.6 2.1 0.46 10.0 0.2 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zinc-ribbons_6 PF07191.12 KXS10306.1 - 0.032 14.2 0.4 0.22 11.5 0.4 1.9 1 1 0 1 1 1 0 zinc-ribbons zf-C2H2_6 PF13912.6 KXS10306.1 - 0.039 14.0 3.6 2.8 8.0 1.7 2.6 2 1 0 2 2 2 0 C2H2-type zinc finger zf-Di19 PF05605.12 KXS10306.1 - 0.04 14.2 0.2 0.06 13.6 0.2 1.3 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-FPG_IleRS PF06827.14 KXS10306.1 - 0.046 13.6 1.5 6.4 6.7 0.1 2.3 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS zf-C4_Topoisom PF01396.19 KXS10306.1 - 0.047 13.5 0.6 1.6 8.6 0.1 2.2 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger LIM PF00412.22 KXS10306.1 - 0.056 13.7 1.1 2.4 8.5 2.6 2.0 1 1 1 2 2 2 0 LIM domain zinc_ribbon_2 PF13240.6 KXS10306.1 - 0.062 13.0 1.6 0.81 9.5 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain DUF1610 PF07754.11 KXS10306.1 - 0.086 12.8 3.3 0.12 12.4 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) Nudix_N_2 PF14803.6 KXS10306.1 - 0.13 12.2 3.0 2.5 8.1 3.0 2.3 1 1 1 2 2 2 0 Nudix N-terminal Zn_Tnp_IS1595 PF12760.7 KXS10306.1 - 0.17 11.9 2.6 0.33 11.0 2.0 1.7 1 1 1 2 2 2 0 Transposase zinc-ribbon domain OrfB_Zn_ribbon PF07282.11 KXS10306.1 - 0.19 11.7 0.7 1.2 9.1 0.7 1.9 1 1 1 2 2 2 0 Putative transposase DNA-binding domain zf_C2H2_13 PF18508.1 KXS10306.1 - 0.21 11.2 1.3 2.1 8.0 0.1 2.1 2 0 0 2 2 2 0 Zinc finger domain zf-ISL3 PF14690.6 KXS10306.1 - 0.22 12.2 0.5 0.22 12.2 0.5 2.0 1 1 1 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf_C2H2_ZHX PF18387.1 KXS10306.1 - 0.24 11.0 3.0 0.23 11.1 1.2 1.7 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain IlvGEDA_leader PF08046.11 KXS10306.1 - 0.41 10.1 2.1 3.5 7.2 0.8 2.0 2 0 0 2 2 2 0 IlvGEDA operon leader peptide CpXC PF14353.6 KXS10306.1 - 0.51 10.4 1.7 1.1 9.3 0.5 1.8 1 1 1 2 2 2 0 CpXC protein zf-AN1 PF01428.16 KXS10306.1 - 4.7 7.4 7.8 10 6.4 0.8 2.3 1 1 1 2 2 2 0 AN1-like Zinc finger zf-C2H2_11 PF16622.5 KXS10306.1 - 7.4 6.4 9.7 1.1 9.1 3.8 2.0 2 0 0 2 2 2 0 zinc-finger C2H2-type SH3_9 PF14604.6 KXS10308.1 - 0.014 15.3 0.3 0.025 14.4 0.3 1.5 1 0 0 1 1 1 0 Variant SH3 domain BTRD1 PF17660.1 KXS10308.1 - 0.062 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial tandem repeat domain 1 Pkinase_Tyr PF07714.17 KXS10309.1 - 3.4e-38 131.4 0.0 1.5e-37 129.3 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase VIT PF08487.10 KXS10309.1 - 1.2e-31 109.2 0.1 2.1e-31 108.4 0.1 1.4 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain Pkinase PF00069.25 KXS10309.1 - 4.7e-29 101.6 0.0 1.3e-28 100.2 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain VWA_3 PF13768.6 KXS10309.1 - 3.2e-16 59.6 0.0 5.9e-16 58.8 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT_2 PF13757.6 KXS10309.1 - 1.5e-10 40.8 0.0 7.2e-10 38.6 0.0 2.1 2 0 0 2 2 2 1 Vault protein inter-alpha-trypsin domain VWA PF00092.28 KXS10309.1 - 9.3e-08 32.5 0.0 1.5e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KXS10309.1 - 3.7e-06 27.5 0.0 3.3e-05 24.5 0.0 2.2 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 KXS10309.1 - 0.0012 18.2 0.0 0.0022 17.4 0.0 1.3 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein PCI PF01399.27 KXS10310.1 - 3e-06 27.7 0.0 0.0063 17.0 0.0 2.7 2 0 0 2 2 2 2 PCI domain BBIP10 PF14777.6 KXS10311.1 - 0.25 10.9 0.0 0.35 10.5 0.0 1.2 1 0 0 1 1 1 0 Cilia BBSome complex subunit 10 Ank_3 PF13606.6 KXS10312.1 - 1.5e-10 40.4 1.2 0.2 12.3 0.0 4.8 4 1 1 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 KXS10312.1 - 1.8e-10 40.8 3.8 0.055 13.8 0.0 4.4 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXS10312.1 - 1.2e-08 35.4 0.9 0.00011 22.7 0.2 3.2 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXS10312.1 - 5.2e-08 33.3 1.3 0.41 11.3 0.0 4.3 5 0 0 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 KXS10312.1 - 2e-07 31.2 5.9 0.34 11.5 0.1 5.1 5 0 0 5 5 5 2 Ankyrin repeat DUF3885 PF13021.6 KXS10312.1 - 0.072 13.2 0.3 4.6 7.4 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3885) Sel1 PF08238.12 KXS10313.1 - 2.1e-49 164.8 30.9 7.2e-08 32.9 0.2 8.3 8 0 0 8 8 8 8 Sel1 repeat ATG27 PF09451.10 KXS10313.1 - 1.5e-25 90.6 0.0 2.4e-25 89.9 0.0 1.2 1 0 0 1 1 1 1 Autophagy-related protein 27 Pkinase_Tyr PF07714.17 KXS10313.1 - 1.3e-05 24.6 0.0 2.6e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase TPR_6 PF13174.6 KXS10313.1 - 0.0045 17.6 8.2 21 6.0 0.0 6.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_16 PF13432.6 KXS10313.1 - 0.011 16.3 20.6 2.2 9.0 3.3 4.6 3 1 2 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 KXS10313.1 - 0.18 11.9 7.7 1.3 9.2 0.3 4.8 3 2 2 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 KXS10313.1 - 3.3 8.1 15.0 12 6.3 1.0 5.0 4 1 0 4 4 4 0 Tetratricopeptide repeat MIT PF04212.18 KXS10313.1 - 4.6 7.4 5.8 15 5.8 0.1 3.8 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain CLASP_N PF12348.8 KXS10314.1 - 1.2e-34 119.8 0.0 3.8e-24 85.5 0.0 4.5 4 0 0 4 4 4 4 CLASP N terminal HEAT PF02985.22 KXS10314.1 - 2.1e-05 24.4 11.8 0.0049 17.0 0.1 6.3 6 0 0 6 6 6 1 HEAT repeat HEAT_2 PF13646.6 KXS10314.1 - 0.00014 22.2 13.6 0.49 10.8 0.4 5.6 3 1 1 5 5 5 3 HEAT repeats Tti2 PF10521.9 KXS10314.1 - 0.0081 15.7 2.3 0.4 10.2 0.9 3.2 3 0 0 3 3 3 1 Tti2 family Spindle_Spc25 PF08234.12 KXS10316.1 - 1e-22 80.1 0.6 2.4e-22 78.9 0.2 1.9 2 0 0 2 2 2 1 Chromosome segregation protein Spc25 GHL13 PF14883.6 KXS10316.1 - 0.036 13.1 1.6 0.05 12.7 1.6 1.2 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase family 13 DASH_Hsk3 PF08227.11 KXS10316.1 - 0.11 12.8 1.1 16 6.0 0.1 3.1 3 0 0 3 3 3 0 DASH complex subunit Hsk3 like DUF3496 PF12001.8 KXS10316.1 - 0.35 11.3 8.1 0.64 10.4 8.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3496) DivIC PF04977.15 KXS10316.1 - 0.91 9.3 7.3 0.23 11.2 0.6 2.7 1 1 2 3 3 3 0 Septum formation initiator DUF465 PF04325.13 KXS10316.1 - 1.1 9.4 8.1 13 5.9 5.3 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF465) TMPIT PF07851.13 KXS10316.1 - 1.1 8.5 3.9 1.4 8.1 3.9 1.2 1 0 0 1 1 1 0 TMPIT-like protein APG6_N PF17675.1 KXS10316.1 - 4.2 7.9 18.4 3.6 8.1 14.4 2.4 1 1 2 3 3 3 0 Apg6 coiled-coil region p450 PF00067.22 KXS10317.1 - 8.7e-76 255.5 0.0 1.1e-75 255.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Amidase PF01425.21 KXS10318.1 - 5.1e-96 322.4 0.0 5.9e-96 322.2 0.0 1.0 1 0 0 1 1 1 1 Amidase p450 PF00067.22 KXS10319.1 - 3.5e-74 250.2 0.0 4.8e-74 249.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Tma16 PF11176.8 KXS10319.1 - 0.085 12.7 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Translation machinery-associated protein 16 zf-C2H2 PF00096.26 KXS10320.1 - 0.071 13.6 0.6 0.16 12.5 0.6 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXS10320.1 - 0.11 13.4 0.3 0.33 11.9 0.3 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger FXR_C1 PF16096.5 KXS10321.1 - 0.048 13.9 3.7 0.12 12.6 3.7 1.7 1 0 0 1 1 1 0 Fragile X-related 1 protein C-terminal region 2 zf-C2H2 PF00096.26 KXS10321.1 - 0.086 13.3 1.4 0.22 12.1 1.4 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type TraT PF05818.12 KXS10321.1 - 0.12 12.1 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein zf-C2H2_4 PF13894.6 KXS10321.1 - 0.19 12.6 0.8 0.53 11.3 0.8 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger Cation_ATPase_C PF00689.21 KXS10322.1 - 3.8e-45 153.8 9.3 3.8e-45 153.8 9.3 2.4 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KXS10322.1 - 4.3e-36 124.1 3.3 4.3e-36 124.1 3.3 3.2 4 0 0 4 4 4 1 E1-E2 ATPase Cation_ATPase PF13246.6 KXS10322.1 - 1.7e-17 63.2 0.0 3.6e-17 62.2 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KXS10322.1 - 3.8e-17 63.3 0.2 1.3e-13 51.7 0.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KXS10322.1 - 4e-09 36.0 0.0 1.2e-07 31.3 0.0 2.6 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KXS10322.1 - 7.3e-06 25.9 1.3 0.00087 19.1 0.7 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase CAMSAP_CKK PF08683.11 KXS10322.1 - 0.0076 16.4 0.0 0.019 15.1 0.0 1.6 1 0 0 1 1 1 1 Microtubule-binding calmodulin-regulated spectrin-associated MFS_1 PF07690.16 KXS10323.1 - 4.7e-27 94.8 36.9 4.7e-27 94.8 36.9 1.5 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF4419 PF14388.6 KXS10324.1 - 1.7e-63 214.9 0.0 2.1e-63 214.5 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) MFS_1 PF07690.16 KXS10325.1 - 7.2e-26 90.9 40.6 7.2e-26 90.9 40.6 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF3938 PF13074.6 KXS10325.1 - 0.072 13.3 0.5 0.42 10.9 0.5 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3938) adh_short PF00106.25 KXS10326.1 - 1.4e-43 148.6 1.4 7.6e-43 146.3 1.4 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXS10326.1 - 2.5e-42 145.0 1.3 2.4e-41 141.8 1.3 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXS10326.1 - 1.6e-06 28.2 0.2 3e-06 27.3 0.1 1.6 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KXS10326.1 - 0.017 14.6 0.0 2.8 7.3 0.0 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family bZIP_2 PF07716.15 KXS10327.1 - 0.21 11.7 7.7 0.38 10.9 7.7 1.3 1 0 0 1 1 1 0 Basic region leucine zipper 4HBT PF03061.22 KXS10330.1 - 3.8e-13 49.6 0.1 8.1e-13 48.5 0.1 1.5 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_2 PF13279.6 KXS10330.1 - 3.1e-06 27.7 0.0 4.3e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.17 KXS10330.1 - 0.00019 20.8 2.9 0.00049 19.5 1.7 1.9 2 0 0 2 2 2 1 Acyl-ACP thioesterase RRM_1 PF00076.22 KXS10331.1 - 5.4e-15 55.0 0.4 8.3e-15 54.4 0.4 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SAPS PF04499.15 KXS10331.1 - 2.7 6.7 5.9 3.3 6.4 5.9 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein TPR_12 PF13424.6 KXS10332.1 - 4.1e-14 52.6 16.1 6.2e-07 29.6 0.0 5.3 5 1 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 KXS10332.1 - 4.2e-10 39.0 15.9 0.82 9.9 0.1 8.1 7 2 1 8 8 8 4 Tetratricopeptide repeat TPR_1 PF00515.28 KXS10332.1 - 1.4e-06 27.8 18.1 0.042 13.7 0.0 6.9 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.6 KXS10332.1 - 8.1e-06 25.7 10.4 0.76 10.1 0.8 5.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_6 PF13174.6 KXS10332.1 - 0.014 16.0 8.1 31 5.5 0.1 6.9 7 2 0 7 7 7 0 Tetratricopeptide repeat ANAPC5 PF12862.7 KXS10332.1 - 0.046 13.8 11.0 0.72 10.0 0.1 3.6 4 1 0 4 4 4 0 Anaphase-promoting complex subunit 5 HicB_lk_antitox PF15919.5 KXS10332.1 - 0.13 12.4 0.1 0.59 10.2 0.0 2.2 2 1 0 2 2 2 0 HicB_like antitoxin of bacterial toxin-antitoxin system TPR_10 PF13374.6 KXS10332.1 - 0.77 9.7 12.9 2.7 8.0 0.0 5.4 7 0 0 7 7 7 0 Tetratricopeptide repeat ArnB_C PF18677.1 KXS10332.1 - 1.8 8.7 7.7 0.25 11.5 2.0 2.5 2 1 0 2 2 2 0 Archaellum regulatory network B, C-terminal domain PCRF PF03462.18 KXS10332.1 - 2.8 7.8 9.2 2.9 7.7 1.3 2.7 2 1 0 2 2 2 0 PCRF domain TMPIT PF07851.13 KXS10332.1 - 4.4 6.5 5.2 0.86 8.8 0.8 1.8 2 0 0 2 2 2 0 TMPIT-like protein PEMT PF04191.13 KXS10333.1 - 2.6e-28 98.5 1.2 5.2e-28 97.6 1.2 1.4 1 0 0 1 1 1 1 Phospholipid methyltransferase ICMT PF04140.14 KXS10333.1 - 0.08 13.4 0.2 0.23 11.9 0.2 1.8 1 1 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family CDC27 PF09507.10 KXS10334.1 - 2.6 7.3 10.6 5.2 6.4 10.6 1.4 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 CAP PF00188.26 KXS10335.1 - 3.1e-39 134.7 13.1 5.3e-20 72.5 1.0 3.2 3 0 0 3 3 3 3 Cysteine-rich secretory protein family Herpes_UL36 PF03586.13 KXS10335.1 - 4.9e-05 22.8 3.3 0.16 11.3 0.1 3.1 3 0 0 3 3 3 2 Herpesvirus UL36 tegument protein Preseq_ALAS PF09029.10 KXS10335.1 - 0.11 12.9 0.8 13 6.3 0.1 3.1 3 0 0 3 3 3 0 5-aminolevulinate synthase presequence CAP_N PF01213.19 KXS10335.1 - 3.2 7.1 24.3 1.1 8.7 2.7 2.5 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal CrtC PF07143.11 KXS10336.1 - 3.5e-05 24.5 0.5 0.00026 21.7 0.5 2.0 1 1 0 1 1 1 1 CrtC N-terminal lipocalin domain V-SNARE PF05008.15 KXS10337.1 - 2.6e-14 53.3 5.9 1e-13 51.4 5.9 2.0 1 0 0 1 1 1 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.8 KXS10337.1 - 7e-14 51.9 8.5 7.4e-14 51.8 3.7 2.5 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 KXS10337.1 - 0.0033 17.3 1.8 0.014 15.3 0.1 2.6 2 1 1 3 3 3 1 Sec20 Fusion_gly PF00523.18 KXS10337.1 - 0.0042 15.4 2.1 0.0085 14.4 0.3 2.0 2 0 0 2 2 2 1 Fusion glycoprotein F0 DUF745 PF05335.13 KXS10337.1 - 0.0044 16.7 6.6 0.018 14.8 1.9 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF745) Synaptobrevin PF00957.21 KXS10337.1 - 0.005 16.6 0.8 0.005 16.6 0.8 2.4 2 1 0 2 2 2 1 Synaptobrevin FAM76 PF16046.5 KXS10337.1 - 0.006 16.0 0.4 0.006 16.0 0.4 1.5 2 0 0 2 2 2 1 FAM76 protein DUF4407 PF14362.6 KXS10337.1 - 0.011 15.2 5.1 0.032 13.6 5.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) IL11 PF07400.11 KXS10337.1 - 0.015 15.0 1.4 2.6 7.7 0.3 2.5 1 1 1 2 2 2 0 Interleukin 11 Muted PF14942.6 KXS10337.1 - 0.024 15.0 0.8 0.024 15.0 0.8 1.8 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein SPW PF03779.14 KXS10337.1 - 0.096 12.3 0.6 0.19 11.4 0.6 1.4 1 0 0 1 1 1 0 SPW repeat NA37 PF04245.13 KXS10337.1 - 0.14 11.6 0.0 14 5.0 0.0 2.3 2 0 0 2 2 2 0 37-kD nucleoid-associated bacterial protein Nbl1_Borealin_N PF10444.9 KXS10337.1 - 0.45 10.2 5.8 1.5 8.5 0.7 2.9 1 1 0 2 2 2 0 Nbl1 / Borealin N terminal Exonuc_VII_L PF02601.15 KXS10337.1 - 0.83 9.2 8.2 0.91 9.0 5.7 2.1 1 1 1 2 2 2 0 Exonuclease VII, large subunit COG5 PF10392.9 KXS10337.1 - 2.5 8.3 9.3 0.069 13.3 2.2 2.0 3 0 0 3 3 3 0 Golgi transport complex subunit 5 TMEM135_C_rich PF15982.5 KXS10338.1 - 0.00092 19.8 0.2 0.002 18.7 0.2 1.5 1 0 0 1 1 1 1 N-terminal cysteine-rich region of Transmembrane protein 135 Piwi PF02171.17 KXS10339.1 - 1.4e-09 37.7 0.0 2.1e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Piwi domain zf-C2H2 PF00096.26 KXS10340.1 - 0.0025 18.2 0.3 0.0049 17.3 0.3 1.5 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXS10340.1 - 0.0042 17.8 0.1 0.0094 16.7 0.1 1.6 1 0 0 1 1 1 1 C2H2-type zinc finger Abhydrolase_6 PF12697.7 KXS10342.1 - 1.4e-07 32.3 6.2 1.4e-07 32.3 6.2 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family WD40 PF00400.32 KXS10343.1 - 9.2e-42 140.2 27.7 2.5e-07 31.2 0.4 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.8 KXS10343.1 - 3.6e-08 32.5 4.0 0.019 13.7 0.1 4.1 1 1 3 4 4 4 3 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 KXS10343.1 - 4.7e-07 30.0 0.5 0.072 13.4 0.0 4.4 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KXS10343.1 - 0.069 12.5 0.0 4.3 6.6 0.0 3.0 2 1 1 4 4 4 0 WD40-like domain Sensor PF13796.6 KXS10344.1 - 0.00026 21.1 15.7 0.00026 21.1 15.7 2.0 1 1 1 2 2 2 2 Putative sensor Ras PF00071.22 KXS10345.1 - 1.1e-44 152.0 0.0 1.3e-44 151.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXS10345.1 - 2.1e-11 44.1 0.0 3.1e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 KXS10345.1 - 0.2 11.1 0.0 0.4 10.2 0.0 1.4 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain zf-C2H2 PF00096.26 KXS10346.1 - 0.0084 16.5 0.8 0.028 14.9 0.8 2.0 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_11 PF16622.5 KXS10346.1 - 0.038 13.7 1.1 0.093 12.5 1.1 1.6 1 0 0 1 1 1 0 zinc-finger C2H2-type F-box-like PF12937.7 KXS10349.1 - 0.0032 17.3 0.1 0.008 16.1 0.1 1.7 1 0 0 1 1 1 1 F-box-like ELM2 PF01448.24 KXS10349.1 - 4.4 8.1 5.9 0.69 10.7 0.2 2.6 3 0 0 3 3 3 0 ELM2 domain F-box-like PF12937.7 KXS10353.1 - 0.001 18.9 0.8 0.0028 17.5 0.0 2.2 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 KXS10353.1 - 0.047 13.6 0.0 0.14 12.1 0.0 1.8 1 0 0 1 1 1 0 F-box domain BTB PF00651.31 KXS10354.1 - 9.3e-07 29.1 0.0 1.7e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain DUF5495 PF17599.2 KXS10354.1 - 0.022 15.0 0.0 0.042 14.1 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5495) ZapB PF06005.12 KXS10354.1 - 0.11 13.0 3.9 0.2 12.1 3.9 1.3 1 0 0 1 1 1 0 Cell division protein ZapB TSC22 PF01166.18 KXS10354.1 - 0.13 12.6 1.4 0.25 11.7 1.4 1.4 1 0 0 1 1 1 0 TSC-22/dip/bun family DUF3450 PF11932.8 KXS10354.1 - 0.13 11.5 3.2 0.22 10.8 3.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) JIP_LZII PF16471.5 KXS10354.1 - 0.14 12.3 1.8 0.28 11.4 1.8 1.4 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II Ank_2 PF12796.7 KXS10355.1 - 7.3e-05 23.3 0.1 0.00036 21.1 0.1 2.1 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 KXS10355.1 - 0.00059 20.2 1.0 0.0059 17.0 0.5 2.7 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 KXS10355.1 - 0.0012 19.2 0.3 0.068 13.8 0.1 3.3 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 KXS10355.1 - 0.03 14.6 0.0 0.3 11.5 0.0 2.5 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXS10356.1 - 0.00032 21.2 0.0 0.0036 17.8 0.0 2.6 2 1 1 3 3 3 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXS10356.1 - 0.0014 18.9 0.8 0.0095 16.4 0.1 2.7 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 KXS10356.1 - 0.0014 19.0 2.0 0.0036 17.7 0.1 2.5 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 KXS10356.1 - 0.0023 18.2 0.1 0.13 12.6 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXS10356.1 - 0.13 12.8 0.0 4.3 8.0 0.0 2.5 2 0 0 2 2 2 0 Ankyrin repeats (many copies) ORC6 PF05460.13 KXS10356.1 - 0.27 10.5 4.4 0.37 10.0 4.4 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) CAF1-p150_C2 PF15539.6 KXS10360.1 - 0.15 11.5 0.1 0.56 9.6 0.1 1.7 1 1 1 2 2 2 0 CAF1 complex subunit p150, region binding to CAF1-p60 at C-term KaiB PF07689.12 KXS10365.1 - 0.025 14.3 0.0 0.07 12.9 0.0 1.7 2 0 0 2 2 2 0 KaiB domain Lipase_3 PF01764.25 KXS10367.1 - 1.7e-13 50.6 0.0 3.1e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KXS10367.1 - 0.54 10.8 17.2 0.36 11.4 14.7 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase family PAC2 PF09754.9 KXS10368.1 - 7.9e-13 48.9 0.0 9.2e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 PAC2 family Pkinase PF00069.25 KXS10369.1 - 2.3e-06 27.2 0.0 4e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KXS10369.1 - 0.085 11.6 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Pkinase PF00069.25 KXS10370.1 - 6.4e-05 22.4 0.0 6.4e-05 22.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS10370.1 - 0.00082 18.7 0.0 0.00093 18.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Sel1 PF08238.12 KXS10371.1 - 8.5e-24 83.5 16.4 7.9e-06 26.4 0.0 5.4 5 1 1 6 6 6 5 Sel1 repeat TPR_2 PF07719.17 KXS10371.1 - 2.4 8.5 11.5 4.4 7.7 0.1 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat Sel1 PF08238.12 KXS10372.1 - 7.8e-21 74.1 4.9 1.1e-10 41.8 0.3 3.1 3 0 0 3 3 3 2 Sel1 repeat TPR_1 PF00515.28 KXS10372.1 - 5.7e-05 22.8 5.0 0.3 11.0 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KXS10372.1 - 0.00083 19.3 5.1 0.47 10.7 0.1 3.5 4 0 0 4 4 4 2 Tetratricopeptide repeat SHNi-TPR PF10516.9 KXS10372.1 - 0.0065 15.9 0.6 4.5 6.8 0.0 2.8 3 0 0 3 3 3 2 SHNi-TPR MIT PF04212.18 KXS10372.1 - 0.0098 15.9 0.0 2.6 8.2 0.0 2.3 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain TPR_12 PF13424.6 KXS10372.1 - 0.015 15.6 2.0 0.25 11.6 2.0 2.7 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_11 PF13414.6 KXS10372.1 - 0.023 14.4 5.1 2.1 8.1 0.2 2.8 4 0 0 4 4 4 0 TPR repeat TPR_16 PF13432.6 KXS10372.1 - 0.041 14.5 0.6 0.56 10.9 0.6 2.2 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_7 PF13176.6 KXS10372.1 - 0.11 12.6 1.3 3.1 8.0 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 KXS10372.1 - 0.12 12.7 4.1 9.6 6.7 0.1 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 KXS10372.1 - 1.2 9.2 5.3 18 5.4 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat SH3_9 PF14604.6 KXS10373.1 - 0.00012 21.9 0.0 0.00024 20.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain DUF3138 PF11336.8 KXS10373.1 - 0.19 10.3 0.0 0.27 9.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) NAD_binding_2 PF03446.15 KXS10374.1 - 2.8e-18 66.6 0.0 4.3e-18 66.0 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KXS10374.1 - 9.3e-11 42.0 0.1 2.2e-10 40.9 0.1 1.6 1 1 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase TauD PF02668.16 KXS10377.1 - 6.4e-48 163.9 4.4 4.4e-41 141.5 0.8 2.0 1 1 1 2 2 2 2 Taurine catabolism dioxygenase TauD, TfdA family DJ-1_PfpI PF01965.24 KXS10379.1 - 6.2e-16 58.6 0.0 8.9e-16 58.1 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family GATase PF00117.28 KXS10379.1 - 0.0007 19.4 0.0 0.00093 19.0 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 KXS10379.1 - 0.004 16.8 0.0 0.0061 16.2 0.0 1.4 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Strep_pep PF14404.6 KXS10379.1 - 0.048 13.9 0.0 0.38 11.0 0.0 2.1 2 0 0 2 2 2 0 Ribosomally synthesized peptide in Streptomyces species Methyltransf_16 PF10294.9 KXS10380.1 - 4.3e-18 65.6 0.0 2.2e-13 50.3 0.0 2.2 2 0 0 2 2 2 2 Lysine methyltransferase PrmA PF06325.13 KXS10380.1 - 6.7e-08 32.3 0.1 9.9e-08 31.7 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 KXS10380.1 - 6.5e-05 22.8 0.0 8e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXS10380.1 - 0.0019 17.8 0.0 0.0027 17.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Met_10 PF02475.16 KXS10380.1 - 0.0022 17.7 0.0 0.0029 17.4 0.0 1.1 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_25 PF13649.6 KXS10380.1 - 0.036 14.8 0.0 0.068 13.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 KXS10380.1 - 0.22 11.2 0.0 0.32 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Acyltransferase PF01553.21 KXS10381.1 - 3e-09 36.6 0.0 5.3e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase PilJ PF13675.6 KXS10381.1 - 0.044 13.8 0.6 0.42 10.6 0.0 2.4 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term zf-RING_5 PF14634.6 KXS10383.1 - 3.7e-09 36.4 3.4 4.9e-09 36.0 3.4 1.2 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 KXS10383.1 - 1.3e-06 28.6 3.4 1.8e-06 28.2 3.4 1.3 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 KXS10383.1 - 3.9e-06 26.6 3.4 5.1e-06 26.2 3.4 1.2 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 KXS10383.1 - 3.2e-05 23.7 2.7 5e-05 23.1 2.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXS10383.1 - 0.00023 20.9 4.4 0.00034 20.4 4.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXS10383.1 - 0.00032 20.5 2.6 0.00048 19.9 2.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KXS10383.1 - 0.00099 19.3 2.0 0.0016 18.7 2.0 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KXS10383.1 - 0.0023 17.9 3.3 0.0026 17.7 1.6 1.8 1 1 1 2 2 2 1 RING-type zinc-finger DUF1272 PF06906.11 KXS10383.1 - 0.0093 16.0 3.7 0.015 15.4 3.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1272) zf-P11 PF03854.14 KXS10383.1 - 0.011 15.4 1.4 0.014 15.0 1.4 1.2 1 0 0 1 1 1 0 P-11 zinc finger zinc-ribbons_6 PF07191.12 KXS10383.1 - 0.016 15.2 1.9 0.022 14.7 1.9 1.2 1 0 0 1 1 1 0 zinc-ribbons zf-RING_4 PF14570.6 KXS10383.1 - 0.019 14.8 2.8 0.034 14.0 2.8 1.5 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.6 KXS10383.1 - 0.024 14.5 2.0 0.033 14.1 2.0 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Prok-RING_1 PF14446.6 KXS10383.1 - 0.049 13.6 1.4 0.14 12.1 0.0 2.1 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 DZR PF12773.7 KXS10383.1 - 0.089 12.8 4.2 0.38 10.8 4.4 1.9 1 1 1 2 2 2 0 Double zinc ribbon IBR PF01485.21 KXS10383.1 - 0.63 10.3 4.9 4.4 7.6 5.0 2.0 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain zf-C2H2 PF00096.26 KXS10384.1 - 6.6e-05 23.1 1.3 0.0002 21.7 1.3 1.9 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXS10384.1 - 0.031 15.1 1.4 0.14 13.1 1.4 2.2 1 0 0 1 1 1 0 C2H2-type zinc finger FOXP-CC PF16159.5 KXS10384.1 - 0.034 14.8 0.2 0.099 13.3 0.2 1.8 1 0 0 1 1 1 0 FOXP coiled-coil domain CxC4 PF18717.1 KXS10384.1 - 0.086 12.7 1.6 0.19 11.6 1.6 1.5 1 0 0 1 1 1 0 CxC4 like cysteine cluster associated with KDZ transposases zf-H2C2_2 PF13465.6 KXS10384.1 - 0.34 11.4 7.6 0.53 10.8 1.9 2.5 2 0 0 2 2 2 0 Zinc-finger double domain IPPT PF01715.17 KXS10385.1 - 6.6e-62 209.3 0.0 3.2e-61 207.0 0.0 1.8 1 1 0 1 1 1 1 IPP transferase IPT PF01745.16 KXS10385.1 - 0.064 12.6 0.1 9.5 5.5 0.0 2.2 2 0 0 2 2 2 0 Isopentenyl transferase AAA_18 PF13238.6 KXS10385.1 - 0.32 11.5 1.0 9.5 6.8 0.2 2.3 2 0 0 2 2 2 0 AAA domain 2-oxogl_dehyd_N PF16078.5 KXS10387.1 - 0.1 12.2 3.2 0.32 10.6 3.2 1.9 1 0 0 1 1 1 0 2-oxoglutarate dehydrogenase N-terminus Pet100 PF09803.9 KXS10387.1 - 0.76 10.3 4.2 2.2 8.9 4.2 1.7 1 0 0 1 1 1 0 Pet100 Cyt_c_ox_IV PF12270.8 KXS10388.1 - 0.25 11.5 0.3 3.4 7.8 0.0 2.5 3 0 0 3 3 3 0 Cytochrome c oxidase subunit IV F-box PF00646.33 KXS10389.1 - 0.00039 20.2 0.4 0.00078 19.3 0.4 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KXS10389.1 - 0.004 17.0 0.3 0.019 14.8 0.1 2.1 2 0 0 2 2 2 1 F-box-like AraC_N PF06719.13 KXS10389.1 - 0.018 14.7 0.7 0.29 10.8 0.0 2.2 2 0 0 2 2 2 0 AraC-type transcriptional regulator N-terminus Cyt_c_ox_IV PF12270.8 KXS10390.1 - 0.25 11.5 0.3 3.4 7.8 0.0 2.5 3 0 0 3 3 3 0 Cytochrome c oxidase subunit IV Pirin PF02678.16 KXS10391.1 - 2.9e-31 107.6 0.3 5.4e-31 106.8 0.3 1.4 1 0 0 1 1 1 1 Pirin Cupin_2 PF07883.11 KXS10391.1 - 4.2e-07 29.6 1.9 4.2e-07 29.6 1.9 2.0 2 0 0 2 2 2 1 Cupin domain Pirin_C_2 PF17954.1 KXS10391.1 - 8.7e-07 29.0 0.4 4.2e-05 23.7 0.1 2.8 2 1 0 2 2 2 1 Quercetinase C-terminal cupin domain 2OG-FeII_Oxy PF03171.20 KXS10391.1 - 0.037 14.5 0.1 0.1 13.1 0.1 1.8 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily PrpF PF04303.13 KXS10392.1 - 4.6e-132 440.5 0.4 6.3e-132 440.0 0.4 1.2 1 0 0 1 1 1 1 PrpF protein NYN PF01936.18 KXS10392.1 - 1.1e-11 45.5 0.0 2e-11 44.6 0.0 1.4 1 0 0 1 1 1 1 NYN domain PIN7 PF18475.1 KXS10392.1 - 0.058 14.0 0.0 0.12 13.1 0.0 1.4 1 0 0 1 1 1 0 PIN domain DUF1073 PF06381.11 KXS10392.1 - 0.2 10.4 0.0 0.33 9.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1073) Polysacc_deac_1 PF01522.21 KXS10393.1 - 7.9e-17 61.3 0.0 1.6e-16 60.3 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF4440 PF14534.6 KXS10395.1 - 1.5e-05 25.3 0.1 1.7e-05 25.2 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) p450 PF00067.22 KXS10396.1 - 1.8e-63 214.9 0.0 2.3e-63 214.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Abhydrolase_3 PF07859.13 KXS10398.1 - 2.2e-40 138.8 0.0 3.1e-40 138.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KXS10398.1 - 3e-09 36.2 0.0 4.2e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 KXS10398.1 - 0.0012 18.3 0.2 1.4 8.4 0.0 2.9 2 1 1 3 3 3 2 Prolyl oligopeptidase family COesterase PF00135.28 KXS10398.1 - 0.0099 14.8 0.0 0.029 13.2 0.0 1.6 2 0 0 2 2 2 1 Carboxylesterase family FMO-like PF00743.19 KXS10400.1 - 6.3e-27 94.2 0.0 2.7e-17 62.4 0.0 2.0 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KXS10400.1 - 8.7e-13 48.2 0.0 2.2e-11 43.6 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXS10400.1 - 2.5e-12 46.6 0.0 9.8e-11 41.4 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXS10400.1 - 5.6e-07 30.0 0.0 0.071 13.7 0.1 3.7 4 0 0 4 4 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXS10400.1 - 6.2e-07 28.9 0.1 1.2e-05 24.6 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_oxidored PF12831.7 KXS10400.1 - 3.3e-06 26.7 0.1 8.8e-06 25.3 0.1 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXS10400.1 - 9e-06 25.8 0.1 2.9e-05 24.2 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXS10400.1 - 9.6e-06 25.4 0.2 0.00053 19.7 0.5 2.4 1 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KXS10400.1 - 7e-05 22.1 0.1 0.00057 19.1 0.3 2.2 2 1 1 3 3 3 1 FAD binding domain Shikimate_DH PF01488.20 KXS10400.1 - 0.00087 19.4 0.1 1.3 9.0 0.0 3.2 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase IlvN PF07991.12 KXS10400.1 - 0.001 18.7 0.0 0.02 14.5 0.0 2.3 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain Thi4 PF01946.17 KXS10400.1 - 0.0012 18.1 0.1 0.0025 17.1 0.1 1.4 1 0 0 1 1 1 1 Thi4 family Amino_oxidase PF01593.24 KXS10400.1 - 0.0022 17.4 0.0 0.01 15.2 0.0 1.8 1 1 0 2 2 2 1 Flavin containing amine oxidoreductase HI0933_like PF03486.14 KXS10400.1 - 0.0023 16.7 0.5 0.0059 15.4 0.1 1.8 3 0 0 3 3 3 1 HI0933-like protein FAD_binding_3 PF01494.19 KXS10400.1 - 0.0038 16.5 0.0 0.0072 15.6 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 KXS10400.1 - 0.0049 16.2 0.4 0.0084 15.4 0.0 1.5 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 KXS10400.1 - 0.0069 16.8 0.0 0.44 11.0 0.0 2.4 2 0 0 2 2 2 1 Putative NAD(P)-binding NAD_binding_9 PF13454.6 KXS10400.1 - 0.023 14.7 1.3 0.59 10.1 0.4 3.3 3 1 0 3 3 3 0 FAD-NAD(P)-binding XdhC_C PF13478.6 KXS10400.1 - 0.066 13.7 0.0 0.64 10.5 0.0 2.2 2 0 0 2 2 2 0 XdhC Rossmann domain Indigoidine_A PF04227.12 KXS10401.1 - 5.9e-116 386.9 1.6 8.7e-116 386.3 1.6 1.3 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.24 KXS10401.1 - 1.2e-20 74.1 3.1 2.4e-12 46.8 0.1 3.4 3 1 0 3 3 3 2 pfkB family carbohydrate kinase Sirohm_synth_C PF14823.6 KXS10402.1 - 0.018 14.6 0.0 0.036 13.7 0.0 1.4 1 0 0 1 1 1 0 Sirohaem biosynthesis protein C-terminal PsbY PF06298.11 KXS10402.1 - 0.066 13.1 3.9 0.13 12.2 3.9 1.4 1 0 0 1 1 1 0 Photosystem II protein Y (PsbY) 4HBT_3 PF13622.6 KXS10403.1 - 2.9e-26 93.2 3.6 9.3e-26 91.6 3.6 1.8 1 1 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 KXS10403.1 - 0.011 16.1 0.1 2.6 8.5 0.0 3.0 2 2 0 2 2 2 0 Thioesterase superfamily Oxidored_FMN PF00724.20 KXS10404.1 - 7.4e-52 176.7 0.0 8.9e-52 176.4 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF1912 PF08930.10 KXS10404.1 - 0.0047 17.1 0.1 0.0089 16.2 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1912) zf-C2H2 PF00096.26 KXS10405.1 - 0.043 14.3 1.0 0.079 13.5 1.0 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXS10405.1 - 0.088 13.7 0.4 0.16 12.9 0.4 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger RNase_T PF00929.24 KXS10407.1 - 4.1e-31 108.8 0.0 4.7e-31 108.6 0.0 1.0 1 0 0 1 1 1 1 Exonuclease DUF5051 PF16473.5 KXS10407.1 - 0.099 12.6 0.0 0.15 12.1 0.0 1.5 1 1 0 1 1 1 0 3' exoribonuclease, RNase T-like HAGH_C PF16123.5 KXS10408.1 - 9.1e-22 77.4 0.0 1.4e-21 76.8 0.0 1.3 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 KXS10408.1 - 1.1e-08 35.3 6.8 6.7e-08 32.8 6.8 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KXS10408.1 - 8.2e-05 22.2 1.4 0.00033 20.2 1.4 1.8 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KXS10408.1 - 0.0025 17.7 0.2 0.0041 17.0 0.2 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain RNA_pol_L_2 PF13656.6 KXS10409.1 - 3.2e-28 97.3 0.1 3.7e-28 97.1 0.1 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 KXS10409.1 - 9.1e-08 31.4 0.0 1.2e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Ribosomal_L7Ae PF01248.26 KXS10410.1 - 8.5e-25 86.3 0.6 1.2e-24 85.9 0.6 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 KXS10410.1 - 0.015 15.4 0.0 0.016 15.2 0.0 1.1 1 0 0 1 1 1 0 RNase P subunit Pop3 TOM6p PF15184.6 KXS10411.1 - 0.14 12.0 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial import receptor subunit TOM6 homolog EF-hand_8 PF13833.6 KXS10413.1 - 0.0096 15.8 0.0 0.022 14.6 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 KXS10413.1 - 0.062 12.9 0.1 0.13 11.9 0.1 1.6 1 0 0 1 1 1 0 EF hand SH3_9 PF14604.6 KXS10415.1 - 1.3e-10 41.0 0.0 2.9e-10 39.8 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXS10415.1 - 1.9e-10 40.2 0.0 3.2e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KXS10415.1 - 1.2e-05 24.9 0.0 2.4e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Rax2 PF12768.7 KXS10415.1 - 0.12 11.9 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Beta-APP PF03494.13 KXS10415.1 - 5.6 6.9 6.7 11 5.9 6.7 1.5 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) Fungal_trans PF04082.18 KXS10416.1 - 5.2e-05 22.4 0.0 0.00011 21.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain WES_acyltransf PF03007.16 KXS10418.1 - 4.6e-26 92.2 0.2 1.9e-22 80.3 0.1 2.1 2 0 0 2 2 2 2 Wax ester synthase-like Acyl-CoA acyltransferase domain DUF1298 PF06974.13 KXS10418.1 - 2.2e-10 40.6 0.0 4.4e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1298) Spore_YhaL PF14147.6 KXS10418.1 - 1.3 8.8 3.0 3.2 7.5 3.0 1.7 1 0 0 1 1 1 0 Sporulation protein YhaL ELO PF01151.18 KXS10419.1 - 3.5e-51 174.1 7.8 4.7e-51 173.7 7.8 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family Retrotran_gag_3 PF14244.6 KXS10419.1 - 0.075 12.8 0.1 0.15 11.9 0.1 1.4 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Aldedh PF00171.22 KXS10420.1 - 1.2e-88 297.6 0.0 1.4e-88 297.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KXS10420.1 - 0.03 13.4 0.0 0.12 11.4 0.0 1.8 1 1 0 1 1 1 0 Acyl-CoA reductase (LuxC) NFACT-R_1 PF05670.13 KXS10421.1 - 8.4e-44 148.7 0.1 1.5e-43 147.9 0.1 1.4 1 0 0 1 1 1 1 NFACT protein RNA binding domain cobW PF02492.19 KXS10422.1 - 3e-42 144.2 0.0 4.3e-42 143.7 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 KXS10422.1 - 0.016 15.1 0.0 0.088 12.7 0.0 2.1 2 0 0 2 2 2 0 Cobalamin synthesis protein cobW C-terminal domain RsgA_GTPase PF03193.16 KXS10422.1 - 0.075 12.9 0.1 8.2 6.3 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 KXS10422.1 - 0.13 12.7 0.0 0.24 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain LtrA PF06772.11 KXS10423.1 - 3e-46 158.3 25.5 6.7e-46 157.1 25.6 1.5 1 1 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) FtsL PF04999.13 KXS10423.1 - 0.96 9.5 4.3 37 4.4 0.0 3.3 3 0 0 3 3 3 0 Cell division protein FtsL Peptidase_M24 PF00557.24 KXS10425.1 - 5e-47 160.3 0.0 7e-47 159.8 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 KXS10425.1 - 6.3e-27 93.7 0.0 1e-26 93.1 0.0 1.3 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain ALAD PF00490.21 KXS10426.1 - 2.8e-121 404.6 0.0 3.4e-121 404.3 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase DUF1068 PF06364.12 KXS10427.1 - 0.037 13.9 3.5 0.055 13.3 3.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1068) Pinin_SDK_N PF04697.13 KXS10428.1 - 0.071 13.8 1.5 0.17 12.5 1.5 1.6 1 0 0 1 1 1 0 pinin/SDK conserved region DAP10 PF07213.11 KXS10430.1 - 0.06 13.3 0.4 0.14 12.1 0.4 1.6 1 0 0 1 1 1 0 DAP10 membrane protein Podoplanin PF05808.11 KXS10430.1 - 1.4 9.0 5.2 4.1 7.5 0.0 2.9 3 0 0 3 3 3 0 Podoplanin Amidohydro_1 PF01979.20 KXS10431.1 - 2.8e-72 243.9 0.0 3.6e-72 243.6 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KXS10431.1 - 9.2e-15 55.1 0.3 7.9e-11 42.1 0.0 2.6 3 0 0 3 3 3 2 Amidohydrolase family Peptidase_C48 PF02902.19 KXS10432.1 - 2.1e-14 53.9 0.0 6.2e-14 52.3 0.0 1.7 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Peptidase_S9 PF00326.21 KXS10433.1 - 7.3e-28 97.5 0.0 1.1e-27 96.9 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KXS10433.1 - 3e-08 33.6 1.0 0.0024 17.6 2.0 2.7 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXS10433.1 - 8e-07 28.6 0.1 0.0014 18.0 0.2 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 DLH PF01738.18 KXS10433.1 - 0.00093 18.8 0.0 0.0019 17.8 0.0 1.4 1 0 0 1 1 1 1 Dienelactone hydrolase family PD40 PF07676.12 KXS10433.1 - 0.0038 17.1 0.8 4.9 7.2 0.1 3.2 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat Abhydrolase_3 PF07859.13 KXS10433.1 - 0.0095 15.8 0.0 0.047 13.6 0.0 2.1 2 1 0 2 2 2 1 alpha/beta hydrolase fold DUF2618 PF10940.8 KXS10433.1 - 0.027 14.3 0.4 0.065 13.1 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2618) FSH1 PF03959.13 KXS10433.1 - 0.17 11.5 0.0 0.29 10.8 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) zf-C2H2 PF00096.26 KXS10434.1 - 1.3e-07 31.6 6.1 0.00035 20.9 2.1 2.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KXS10434.1 - 1.5e-07 31.5 5.8 5.7e-07 29.7 1.2 2.3 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KXS10434.1 - 0.00013 22.5 5.3 0.023 15.5 2.1 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger FOXP-CC PF16159.5 KXS10434.1 - 0.014 16.0 2.3 0.079 13.6 0.2 2.0 1 1 1 2 2 2 0 FOXP coiled-coil domain CHORD PF04968.12 KXS10434.1 - 0.05 14.3 1.5 2.2 9.0 0.7 2.0 1 1 1 2 2 2 0 CHORD IBR PF01485.21 KXS10434.1 - 0.051 13.8 0.4 0.55 10.5 0.4 1.9 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain zf-C2H2_aberr PF17017.5 KXS10434.1 - 0.15 12.2 1.4 3.1 7.9 0.1 2.0 1 1 1 2 2 2 0 Aberrant zinc-finger Peptidase_S10 PF00450.22 KXS10435.1 - 8.6e-124 414.1 0.0 1.1e-123 413.8 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Ank_5 PF13857.6 KXS10436.1 - 7.8e-05 22.9 0.2 0.39 11.1 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXS10436.1 - 0.0031 18.0 0.1 2 9.1 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXS10436.1 - 0.0071 16.8 0.3 2.6 8.9 0.1 2.4 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 KXS10436.1 - 0.0089 16.6 0.3 0.1 13.2 0.3 2.0 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) 2OG-FeII_Oxy_3 PF13640.6 KXS10437.1 - 0.16 12.9 0.0 0.32 11.9 0.0 1.6 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Amidase PF01425.21 KXS10438.1 - 2e-84 284.2 0.0 3.3e-84 283.4 0.0 1.3 1 1 0 1 1 1 1 Amidase PMP22_Claudin PF00822.20 KXS10440.1 - 0.1 12.5 1.1 0.23 11.3 0.4 1.8 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin family Pox_D5 PF03288.16 KXS10440.1 - 0.11 12.9 0.5 0.31 11.5 0.1 1.9 2 0 0 2 2 2 0 Poxvirus D5 protein-like Peptidase_M13_N PF05649.13 KXS10441.1 - 1.4e-91 308.0 0.0 2e-91 307.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 KXS10441.1 - 3.5e-59 199.9 0.0 5.6e-59 199.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M13 Acetyltransf_10 PF13673.7 KXS10445.1 - 3.1e-10 40.1 0.0 1.8e-09 37.6 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXS10445.1 - 2.2e-09 37.6 0.0 4.9e-09 36.4 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXS10445.1 - 3.5e-06 27.3 0.0 5.7e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PanZ PF12568.8 KXS10445.1 - 0.0024 17.6 0.0 0.011 15.5 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_9 PF13527.7 KXS10445.1 - 0.0074 16.4 0.0 0.041 14.0 0.0 2.2 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 KXS10445.1 - 0.032 14.2 0.1 0.061 13.3 0.1 1.4 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase FR47 PF08445.10 KXS10445.1 - 0.065 13.2 0.0 0.2 11.7 0.0 1.8 1 1 0 1 1 1 0 FR47-like protein MS_channel PF00924.18 KXS10446.1 - 3e-17 62.9 4.0 5.2e-17 62.1 4.0 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel 7tm_7 PF08395.12 KXS10446.1 - 0.00094 18.5 5.1 0.00094 18.5 5.1 1.9 2 0 0 2 2 2 1 7tm Chemosensory receptor EF-hand_1 PF00036.32 KXS10446.1 - 0.0032 16.9 0.0 0.0076 15.7 0.0 1.6 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KXS10446.1 - 0.0079 16.0 0.0 0.023 14.6 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.6 KXS10446.1 - 0.011 15.3 0.0 0.03 13.8 0.0 1.8 2 0 0 2 2 2 0 EF hand EF-hand_7 PF13499.6 KXS10446.1 - 0.07 13.6 0.1 0.16 12.4 0.1 1.6 1 0 0 1 1 1 0 EF-hand domain pair WaaY PF06176.11 KXS10447.1 - 0.0055 16.4 0.0 0.0055 16.4 0.0 1.0 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) Pkinase PF00069.25 KXS10447.1 - 0.024 14.0 0.0 0.024 14.0 0.0 1.0 1 0 0 1 1 1 0 Protein kinase domain 3-HAO PF06052.12 KXS10449.1 - 4.7e-50 169.1 0.1 8.8e-49 165.0 0.1 2.0 1 1 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.11 KXS10449.1 - 0.00043 19.9 0.0 0.00066 19.3 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 KXS10449.1 - 0.00084 19.0 0.0 0.0011 18.6 0.0 1.1 1 0 0 1 1 1 1 Cupin zf-TFIIB PF13453.6 KXS10449.1 - 0.00085 18.6 1.2 0.058 12.7 0.1 2.6 2 0 0 2 2 2 1 Transcription factor zinc-finger DZR PF12773.7 KXS10449.1 - 0.00099 19.1 1.5 0.0016 18.5 1.5 1.3 1 0 0 1 1 1 1 Double zinc ribbon Zn_Tnp_IS1595 PF12760.7 KXS10449.1 - 0.004 17.1 4.4 0.014 15.4 1.0 2.3 2 0 0 2 2 2 1 Transposase zinc-ribbon domain Cupin_3 PF05899.12 KXS10449.1 - 0.017 14.8 0.0 0.03 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Zn-ribbon_8 PF09723.10 KXS10449.1 - 0.052 13.7 1.8 0.062 13.4 0.1 2.0 1 1 0 1 1 1 0 Zinc ribbon domain AraC_binding PF02311.19 KXS10449.1 - 0.076 12.9 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 AraC-like ligand binding domain zf-ACC PF17848.1 KXS10449.1 - 0.094 12.8 1.2 7.3 6.8 0.0 2.3 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain zf-ribbon_3 PF13248.6 KXS10449.1 - 0.28 10.6 0.3 0.28 10.6 0.3 2.0 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_2 PF13240.6 KXS10449.1 - 1 9.1 5.0 0.41 10.4 0.3 2.5 2 0 0 2 2 2 0 zinc-ribbon domain Nudix_N_2 PF14803.6 KXS10449.1 - 1.6 8.7 7.8 4.5 7.3 0.5 2.7 2 1 0 2 2 2 0 Nudix N-terminal RmlD_sub_bind PF04321.17 KXS10450.1 - 3.7e-49 167.4 0.0 5.6e-47 160.2 0.0 2.0 2 0 0 2 2 2 2 RmlD substrate binding domain Epimerase PF01370.21 KXS10450.1 - 3.5e-20 72.5 0.0 4.9e-20 72.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KXS10450.1 - 4e-07 29.5 0.4 3.9e-05 23.0 0.0 2.6 2 1 0 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.15 KXS10450.1 - 4.3e-07 29.4 0.4 1.6e-05 24.2 0.0 2.5 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KXS10450.1 - 1e-06 28.4 0.0 1.7e-06 27.6 0.0 1.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Nup160 PF11715.8 KXS10452.1 - 1.1e-05 24.3 0.0 3.5e-05 22.6 0.0 1.7 1 1 0 1 1 1 1 Nucleoporin Nup120/160 SRP-alpha_N PF04086.13 KXS10455.1 - 7 6.5 18.4 9.9 6.0 18.4 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal RCC1 PF00415.18 KXS10456.1 - 5.2e-07 30.2 0.0 0.0095 16.5 0.0 3.5 3 0 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat Pkinase PF00069.25 KXS10458.1 - 1.6e-68 230.9 0.0 2.2e-68 230.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS10458.1 - 2.5e-32 112.2 0.0 3.6e-32 111.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXS10458.1 - 1.2e-08 34.7 0.0 2.5e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KXS10458.1 - 0.00067 19.6 0.4 0.011 15.7 0.0 2.7 2 2 0 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 KXS10458.1 - 0.00098 18.5 0.0 0.0032 16.8 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KXS10458.1 - 0.0081 15.8 0.3 0.044 13.4 0.0 2.1 2 0 0 2 2 2 1 Choline/ethanolamine kinase KA1 PF02149.19 KXS10458.1 - 0.012 15.4 0.0 0.025 14.4 0.0 1.5 1 0 0 1 1 1 0 Kinase associated domain 1 Haspin_kinase PF12330.8 KXS10458.1 - 0.051 12.5 0.0 0.12 11.2 0.0 1.6 1 0 0 1 1 1 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 KXS10458.1 - 0.063 12.3 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 SH3_1 PF00018.28 KXS10459.1 - 7.4e-26 89.5 0.5 1.1e-12 47.4 0.0 2.3 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 KXS10459.1 - 3.2e-24 84.5 0.8 3.9e-11 42.6 0.0 2.3 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.17 KXS10459.1 - 3e-19 68.5 0.2 1.3e-11 44.0 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain C1_1 PF00130.22 KXS10459.1 - 1.8e-11 43.8 5.7 2.9e-11 43.1 5.7 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_3 PF08239.11 KXS10459.1 - 5.5e-11 42.6 1.6 0.00033 20.9 0.1 2.5 2 0 0 2 2 2 2 Bacterial SH3 domain C1_2 PF03107.16 KXS10459.1 - 0.0015 18.8 1.4 0.0028 17.9 1.4 1.5 1 0 0 1 1 1 1 C1 domain SH3_18 PF18354.1 KXS10459.1 - 0.042 13.9 0.0 2.8 8.0 0.0 2.3 2 0 0 2 2 2 0 CarS bacterial SH3 domain SH3_16 PF18348.1 KXS10459.1 - 0.15 11.9 0.1 13 5.7 0.0 2.5 2 0 0 2 2 2 0 Bacterial dipeptidyl-peptidase Sh3 domain DZR PF12773.7 KXS10459.1 - 1.1 9.4 5.5 2.2 8.4 5.5 1.5 1 0 0 1 1 1 0 Double zinc ribbon zf-RING_2 PF13639.6 KXS10460.1 - 1.7e-07 31.5 30.9 6.4e-07 29.6 4.8 4.1 3 1 0 3 3 3 2 Ring finger domain zf-C3HC4_2 PF13923.6 KXS10460.1 - 0.0028 17.4 5.0 0.0028 17.4 5.0 3.9 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 KXS10460.1 - 0.015 15.2 1.3 0.015 15.2 1.3 3.0 3 0 0 3 3 3 0 PHD-finger zf-RING_11 PF17123.5 KXS10460.1 - 0.018 14.8 1.0 0.018 14.8 1.0 3.3 4 0 0 4 4 4 0 RING-like zinc finger zf-ANAPC11 PF12861.7 KXS10460.1 - 0.019 15.0 1.4 0.019 15.0 1.4 3.2 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING-like PF08746.11 KXS10460.1 - 3.5 8.0 14.5 4.5 7.7 2.6 2.8 2 0 0 2 2 2 0 RING-like domain GAIN_A PF18619.1 KXS10461.1 - 0.17 12.1 1.4 0.37 11.0 0.3 1.9 2 0 0 2 2 2 0 GPCR-Autoproteolysis-INducing (GAIN) subdomain A HA2 PF04408.23 KXS10462.1 - 3.8e-19 69.0 5.6 6.5e-19 68.2 0.0 3.4 3 0 0 3 3 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KXS10462.1 - 2.7e-18 66.1 0.0 1.7e-17 63.5 0.0 2.3 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KXS10462.1 - 1.6e-13 51.0 0.1 3.5e-13 49.9 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KXS10462.1 - 1.1e-08 35.1 0.0 2.2e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase RWD PF05773.22 KXS10462.1 - 1.9e-05 24.9 0.0 4.6e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 RWD domain AAA_22 PF13401.6 KXS10462.1 - 0.00062 20.0 2.0 0.0013 19.0 0.1 2.4 2 1 0 2 2 2 1 AAA domain ATPase PF06745.13 KXS10462.1 - 0.00064 19.1 0.0 0.0015 18.0 0.0 1.5 1 0 0 1 1 1 1 KaiC ABC_tran PF00005.27 KXS10462.1 - 0.06 13.9 0.2 0.32 11.5 0.0 2.3 2 0 0 2 2 2 0 ABC transporter UBA PF00627.31 KXS10462.1 - 0.11 12.4 0.0 4.9 7.2 0.0 3.3 3 0 0 3 3 3 0 UBA/TS-N domain PaaX PF07848.12 KXS10462.1 - 0.12 12.7 0.1 36 4.7 0.0 3.5 3 0 0 3 3 3 0 PaaX-like protein T2SSM PF04612.12 KXS10462.1 - 0.44 10.6 6.2 0.24 11.4 1.9 2.7 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein M AAA_23 PF13476.6 KXS10462.1 - 0.54 10.7 7.6 4.9 7.6 0.0 2.9 3 0 0 3 3 2 0 AAA domain DUF4436 PF14494.6 KXS10463.1 - 1e-19 70.8 0.5 1e-19 70.8 0.5 1.7 2 1 0 2 2 2 1 Domain of unknown function (DUF4436) DUF5325 PF17259.2 KXS10463.1 - 0.031 14.2 0.4 0.031 14.2 0.4 2.3 3 0 0 3 3 3 0 Family of unknown function (DUF5325) Yip1 PF04893.17 KXS10463.1 - 8.3 6.1 13.2 0.9 9.2 3.0 2.7 3 0 0 3 3 3 0 Yip1 domain DUF4436 PF14494.6 KXS10466.1 - 5.9e-20 71.6 0.6 8.9e-20 71.1 0.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4436) MS_channel PF00924.18 KXS10468.1 - 1.9e-11 43.9 1.5 4.3e-11 42.7 1.5 1.5 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.32 KXS10468.1 - 0.0014 18.0 0.0 0.0035 16.8 0.0 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KXS10468.1 - 0.0032 17.3 0.0 0.0087 15.9 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain MIS13 PF08202.11 KXS10468.1 - 0.035 13.4 1.1 0.062 12.6 0.0 1.9 2 0 0 2 2 2 0 Mis12-Mtw1 protein family DUF1140 PF06600.11 KXS10468.1 - 0.044 14.2 0.8 0.11 12.9 0.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1140) EF-hand_5 PF13202.6 KXS10468.1 - 0.087 12.4 0.0 0.31 10.6 0.0 2.0 2 0 0 2 2 2 0 EF hand EF-hand_7 PF13499.6 KXS10468.1 - 0.13 12.7 0.0 0.43 11.1 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair MS_channel PF00924.18 KXS10469.1 - 5.1e-15 55.6 6.1 9.4e-15 54.7 6.1 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_6 PF13405.6 KXS10469.1 - 0.011 15.6 0.0 0.034 14.1 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain EF-hand_1 PF00036.32 KXS10469.1 - 0.014 14.9 0.0 0.034 13.7 0.0 1.7 1 0 0 1 1 1 0 EF hand EMC3_TMCO1 PF01956.16 KXS10469.1 - 0.026 14.3 0.4 0.026 14.3 0.4 2.1 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like Orai-1 PF07856.12 KXS10469.1 - 0.049 13.3 7.4 0.057 13.1 0.1 3.0 3 0 0 3 3 3 0 Mediator of CRAC channel activity EF-hand_5 PF13202.6 KXS10469.1 - 0.051 13.1 0.0 0.19 11.3 0.0 2.0 2 0 0 2 2 2 0 EF hand ATP_synt_H PF05493.13 KXS10469.1 - 2.2 8.8 8.0 21 5.7 2.2 2.9 2 0 0 2 2 2 0 ATP synthase subunit H PQ-loop PF04193.14 KXS10472.1 - 1.8e-28 98.1 12.3 2.8e-16 59.0 3.6 3.4 4 0 0 4 4 4 2 PQ loop repeat Fungal_trans PF04082.18 KXS10473.1 - 7e-10 38.4 3.8 1.2e-09 37.6 3.8 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF4449 PF14613.6 KXS10476.1 - 2.3e-08 34.3 0.2 2.3e-08 34.3 0.2 4.7 4 1 0 5 5 5 1 Protein of unknown function (DUF4449) Collagen_mid PF15984.5 KXS10476.1 - 0.00044 20.1 0.0 0.0022 17.8 0.0 2.2 2 0 0 2 2 2 1 Bacterial collagen, middle region Com_YlbF PF06133.11 KXS10476.1 - 0.055 14.1 0.6 0.055 14.1 0.6 3.6 3 1 1 4 4 4 0 Control of competence regulator ComK, YlbF/YmcA ARTD15_N PF18084.1 KXS10476.1 - 0.15 12.3 0.0 0.56 10.5 0.0 2.0 1 0 0 1 1 1 0 ARTD15 N-terminal domain CBFD_NFYB_HMF PF00808.23 KXS10476.1 - 1.3 9.4 4.8 15 6.0 0.0 4.6 5 0 0 5 5 5 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PCI PF01399.27 KXS10482.1 - 2.9e-13 50.2 0.2 6.2e-13 49.2 0.2 1.6 1 0 0 1 1 1 1 PCI domain Pkinase PF00069.25 KXS10484.1 - 1.3e-53 182.0 0.0 1.7e-53 181.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS10484.1 - 2.4e-20 72.9 0.0 3e-20 72.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 KXS10484.1 - 0.0031 17.2 0.0 0.33 10.5 0.0 2.1 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 KXS10484.1 - 0.025 14.0 0.1 0.35 10.2 0.0 2.1 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KXS10484.1 - 0.18 10.5 0.0 0.22 10.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Pkinase PF00069.25 KXS10487.1 - 1.1e-68 231.5 0.0 1.3e-68 231.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS10487.1 - 1e-38 133.1 0.0 1.3e-38 132.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXS10487.1 - 4.9e-07 29.3 0.0 8.3e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KXS10487.1 - 0.00012 21.5 0.0 0.00017 21.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KXS10487.1 - 0.00081 19.0 0.0 0.0018 17.9 0.0 1.5 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 KXS10487.1 - 0.0011 18.9 0.1 0.0024 17.8 0.1 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KXS10487.1 - 0.0035 16.4 0.0 0.0045 16.0 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 KXS10487.1 - 0.0039 16.0 0.0 0.0078 15.0 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase Choline_kinase PF01633.20 KXS10487.1 - 0.15 11.7 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase AA_permease_2 PF13520.6 KXS10488.1 - 1e-05 24.6 47.0 0.0011 17.9 24.6 4.0 2 1 1 3 3 3 1 Amino acid permease AA_permease PF00324.21 KXS10488.1 - 0.024 13.2 29.0 0.27 9.8 29.0 2.7 1 1 0 1 1 1 0 Amino acid permease ATXN-1_C PF12547.8 KXS10488.1 - 0.04 14.3 0.5 0.12 12.8 0.5 1.8 1 0 0 1 1 1 0 Capicua transcriptional repressor modulator Methyltransf_23 PF13489.6 KXS10490.1 - 1.1e-16 61.1 0.0 1.4e-16 60.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXS10490.1 - 7.3e-09 36.3 0.0 1.1e-08 35.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXS10490.1 - 9.7e-09 35.8 0.0 2.4e-08 34.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXS10490.1 - 2.2e-06 27.6 0.0 3.4e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXS10490.1 - 2.1e-05 25.1 0.0 4.3e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_17 PF12692.7 KXS10490.1 - 0.028 14.4 0.0 0.045 13.8 0.0 1.2 1 0 0 1 1 1 0 S-adenosyl-L-methionine methyltransferase Ubie_methyltran PF01209.18 KXS10490.1 - 0.15 11.4 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family RRM_1 PF00076.22 KXS10492.1 - 1.8e-21 75.7 0.0 2.7e-21 75.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KXS10492.1 - 0.0017 18.4 0.0 0.0029 17.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif DUF478 PF04334.12 KXS10493.1 - 0.042 13.9 0.3 0.14 12.3 0.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF478) DUF4148 PF13663.6 KXS10493.1 - 9.9 6.4 8.7 0.46 10.7 1.4 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4148) SnoaL_2 PF12680.7 KXS10495.1 - 0.019 15.6 0.6 0.064 13.9 0.0 2.1 3 0 0 3 3 3 0 SnoaL-like domain SpoU_methylase PF00588.19 KXS10497.1 - 2.2e-20 73.3 0.0 5.8e-13 49.2 0.0 2.4 2 0 0 2 2 2 2 SpoU rRNA Methylase family Myosin_N PF02736.19 KXS10499.1 - 0.12 12.3 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain Rap_GAP PF02145.15 KXS10500.1 - 1.6e-60 203.8 0.0 2.1e-60 203.4 0.0 1.2 1 0 0 1 1 1 1 Rap/ran-GAP IFRD_C PF04836.12 KXS10500.1 - 0.038 14.6 0.0 0.13 12.9 0.0 1.9 1 0 0 1 1 1 0 Interferon-related protein conserved region HHH PF00633.23 KXS10501.1 - 0.063 13.2 0.0 0.17 11.9 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix motif Peptidase_M56 PF05569.11 KXS10501.1 - 0.069 12.3 0.2 0.12 11.6 0.2 1.3 1 0 0 1 1 1 0 BlaR1 peptidase M56 Saf_2TM PF18303.1 KXS10501.1 - 0.14 11.7 0.1 0.32 10.6 0.1 1.5 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain tRNA_lig_kinase PF08303.11 KXS10503.1 - 2.2e-35 122.3 0.0 3.9e-35 121.4 0.0 1.4 1 0 0 1 1 1 1 tRNA ligase kinase domain tRNA_lig_CPD PF08302.11 KXS10503.1 - 6.8e-30 104.4 0.0 1e-29 103.8 0.0 1.2 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain AAA_18 PF13238.6 KXS10503.1 - 0.0035 17.9 0.0 0.01 16.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain FAS_N PF17828.1 KXS10503.1 - 0.07 13.1 0.0 0.18 11.8 0.0 1.7 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta LigT_PEase PF02834.16 KXS10503.1 - 0.072 13.3 0.0 4.6 7.5 0.0 2.6 2 0 0 2 2 2 0 LigT like Phosphoesterase adh_short_C2 PF13561.6 KXS10504.1 - 2.6e-51 174.4 2.1 3.1e-50 170.9 2.1 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXS10504.1 - 5.7e-44 149.9 3.0 4.7e-43 146.9 3.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXS10504.1 - 3.3e-07 30.4 1.0 3.3e-07 30.4 1.0 1.6 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KXS10504.1 - 8.1e-06 25.5 0.7 1.7e-05 24.4 0.7 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXS10504.1 - 0.013 14.5 2.8 0.028 13.4 2.8 1.5 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF1120 PF06551.12 KXS10504.1 - 0.014 15.5 1.5 5.4 7.2 0.0 3.4 2 1 0 3 3 3 0 Protein of unknown function (DUF1120) UDPG_MGDP_dh_N PF03721.14 KXS10504.1 - 0.077 12.6 1.2 0.14 11.7 1.2 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.18 KXS10504.1 - 0.18 11.7 0.6 0.37 10.7 0.6 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ABM PF03992.16 KXS10505.1 - 8.9e-20 70.6 0.0 9.9e-20 70.4 0.0 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Cyclase_polyket PF04673.12 KXS10505.1 - 0.1 12.9 0.0 0.13 12.5 0.0 1.2 1 0 0 1 1 1 0 Polyketide synthesis cyclase PhyH PF05721.13 KXS10506.1 - 2.9e-26 93.1 0.0 3.6e-26 92.8 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Toxin_35 PF10530.9 KXS10507.1 - 4.9 7.2 17.8 5.5 7.1 6.1 2.6 2 0 0 2 2 2 0 Toxin with inhibitor cystine knot ICK or Knottin scaffold RNB PF00773.19 KXS10509.1 - 3.5e-44 151.5 0.0 4.7e-44 151.1 0.0 1.1 1 0 0 1 1 1 1 RNB domain MFS_1 PF07690.16 KXS10510.1 - 8.2e-08 31.5 0.7 8.2e-08 31.5 0.7 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily Gag_p6 PF08705.11 KXS10510.1 - 0.039 14.2 0.0 0.13 12.6 0.0 1.8 2 0 0 2 2 2 0 Gag protein p6 MFS_3 PF05977.13 KXS10510.1 - 0.046 12.1 0.8 0.15 10.5 0.1 1.8 2 0 0 2 2 2 0 Transmembrane secretion effector MFS_1 PF07690.16 KXS10511.1 - 2.2e-38 132.1 40.7 2.2e-38 132.1 40.7 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXS10511.1 - 1.4e-09 37.3 8.7 1.4e-09 37.3 8.7 3.0 3 0 0 3 3 3 1 Sugar (and other) transporter MFS_3 PF05977.13 KXS10511.1 - 0.0018 16.7 7.4 0.0028 16.1 7.4 1.3 1 0 0 1 1 1 1 Transmembrane secretion effector NUDIX PF00293.28 KXS10512.1 - 0.0021 18.1 0.1 0.29 11.2 0.0 2.5 2 1 0 2 2 2 2 NUDIX domain NUDIX_4 PF14815.6 KXS10512.1 - 0.084 12.9 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 NUDIX domain F-box-like PF12937.7 KXS10513.1 - 1.6e-08 34.3 0.9 3.2e-08 33.3 0.9 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXS10513.1 - 0.00012 21.8 1.2 0.00024 20.9 1.2 1.5 1 0 0 1 1 1 1 F-box domain PQQ_3 PF13570.6 KXS10513.1 - 0.024 15.1 1.1 13 6.4 0.1 3.0 2 0 0 2 2 2 0 PQQ-like domain SnoaL_2 PF12680.7 KXS10515.1 - 3.2e-06 27.7 0.0 3.8e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 KXS10515.1 - 3.3e-06 27.5 0.0 3.9e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_3 PF13474.6 KXS10515.1 - 0.0021 18.3 0.0 0.0025 18.0 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain ABM PF03992.16 KXS10518.1 - 4e-14 52.5 0.0 4.9e-14 52.2 0.0 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Dehydratase_hem PF13816.6 KXS10518.1 - 0.12 11.8 0.0 0.13 11.6 0.0 1.0 1 0 0 1 1 1 0 Haem-containing dehydratase MFS_1 PF07690.16 KXS10519.1 - 4.3e-15 55.5 44.1 4.3e-15 55.5 44.1 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily Pyr_redox_2 PF07992.14 KXS10520.1 - 2.4e-20 73.0 3.6 1.7e-14 53.7 0.3 3.1 1 1 2 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXS10520.1 - 5.1e-08 33.4 1.3 1.6e-06 28.6 0.6 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXS10520.1 - 8.1e-06 25.2 0.1 1.7e-05 24.1 0.1 1.4 1 1 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KXS10520.1 - 8.5e-05 21.9 0.4 0.00022 20.6 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXS10520.1 - 9.6e-05 21.7 0.9 0.028 13.7 0.1 2.9 2 1 0 3 3 3 1 Thi4 family DAO PF01266.24 KXS10520.1 - 0.00099 18.8 5.4 0.083 12.5 0.6 3.2 2 1 1 3 3 3 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KXS10520.1 - 0.0013 17.8 0.1 0.015 14.4 0.0 2.5 3 0 0 3 3 3 1 Lycopene cyclase protein Trp_halogenase PF04820.14 KXS10520.1 - 0.0037 16.2 1.8 1.1 8.0 0.2 3.0 2 1 1 3 3 3 1 Tryptophan halogenase NAD_binding_8 PF13450.6 KXS10520.1 - 0.0039 17.4 0.2 1 9.6 0.1 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain TrkA_N PF02254.18 KXS10520.1 - 0.0052 17.0 0.7 0.019 15.2 0.3 2.0 2 0 0 2 2 2 1 TrkA-N domain FAD_binding_2 PF00890.24 KXS10520.1 - 0.017 14.2 0.0 0.1 11.7 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain NAD_binding_9 PF13454.6 KXS10520.1 - 0.023 14.7 2.7 0.42 10.6 2.7 2.8 1 1 0 1 1 1 0 FAD-NAD(P)-binding PALP PF00291.25 KXS10520.1 - 0.048 13.1 0.0 0.07 12.5 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme 3HCDH_N PF02737.18 KXS10520.1 - 0.056 13.3 0.3 0.089 12.7 0.3 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF3236 PF11576.8 KXS10520.1 - 0.17 11.6 0.2 1.3 8.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3236) HI0933_like PF03486.14 KXS10520.1 - 0.18 10.5 0.1 0.7 8.5 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein Plavaka PF18759.1 KXS10522.1 - 0.0018 17.6 0.0 0.0029 16.9 0.0 1.3 1 0 0 1 1 1 1 Plavaka transposase Pkinase PF00069.25 KXS10524.1 - 3.1e-68 230.0 0.0 4e-68 229.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS10524.1 - 2.5e-38 131.9 0.0 3.4e-38 131.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXS10524.1 - 2.2e-06 27.2 0.0 3.5e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KXS10524.1 - 0.00052 19.4 0.0 0.0011 18.4 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXS10524.1 - 0.0013 18.8 0.1 0.0037 17.2 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 KXS10524.1 - 0.0029 17.2 0.0 0.006 16.2 0.0 1.5 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 KXS10524.1 - 0.0074 15.3 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 KXS10524.1 - 0.0077 15.1 0.0 0.017 13.9 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 KXS10524.1 - 0.14 11.2 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 AA_permease_2 PF13520.6 KXS10525.1 - 7.3e-47 160.1 51.8 9.7e-47 159.7 51.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXS10525.1 - 1.6e-17 63.3 44.8 2.2e-17 62.9 44.8 1.1 1 0 0 1 1 1 1 Amino acid permease Methyltransf_23 PF13489.6 KXS10526.1 - 6.8e-17 61.8 0.0 8.5e-17 61.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXS10526.1 - 1e-08 35.7 0.0 2.6e-08 34.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXS10526.1 - 1.8e-08 35.1 0.0 2.7e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXS10526.1 - 6.1e-06 26.1 0.0 1e-05 25.4 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXS10526.1 - 9.5e-05 23.0 0.0 0.00023 21.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_17 PF12692.7 KXS10526.1 - 0.018 15.0 0.0 0.028 14.4 0.0 1.2 1 0 0 1 1 1 0 S-adenosyl-L-methionine methyltransferase Ubie_methyltran PF01209.18 KXS10526.1 - 0.22 10.8 0.0 0.32 10.3 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family RRM_1 PF00076.22 KXS10528.1 - 1.8e-21 75.7 0.0 2.7e-21 75.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KXS10528.1 - 0.0017 18.4 0.0 0.0029 17.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif FAM196 PF15265.6 KXS10531.1 - 0.075 12.5 0.0 0.075 12.5 0.0 3.3 2 1 1 3 3 3 0 FAM196 family Dehydrin PF00257.19 KXS10532.1 - 2.6e-05 24.9 3.1 2.6e-05 24.9 3.1 1.7 2 0 0 2 2 2 1 Dehydrin SnoaL_2 PF12680.7 KXS10532.1 - 0.025 15.2 0.6 0.09 13.4 0.0 2.1 3 0 0 3 3 3 0 SnoaL-like domain Rap_GAP PF02145.15 KXS10536.1 - 1.1e-61 207.7 0.0 1.4e-61 207.3 0.0 1.2 1 0 0 1 1 1 1 Rap/ran-GAP IFRD_C PF04836.12 KXS10536.1 - 0.04 14.5 0.0 0.13 12.9 0.0 1.9 1 0 0 1 1 1 0 Interferon-related protein conserved region CybS PF05328.12 KXS10537.1 - 0.027 14.1 0.3 0.067 12.9 0.3 1.6 1 0 0 1 1 1 0 CybS, succinate dehydrogenase cytochrome B small subunit Peptidase_M56 PF05569.11 KXS10537.1 - 0.11 11.7 0.1 0.27 10.4 0.1 1.6 1 0 0 1 1 1 0 BlaR1 peptidase M56 Ion_trans PF00520.31 KXS10537.1 - 5.2 6.2 8.0 6.3 6.0 0.1 2.7 3 1 0 3 3 3 0 Ion transport protein RNA_lig_T4_1 PF09511.10 KXS10539.1 - 1.6e-76 257.0 0.0 2.6e-76 256.3 0.0 1.4 1 0 0 1 1 1 1 RNA ligase tRNA_lig_kinase PF08303.11 KXS10539.1 - 1.5e-36 126.0 0.1 3.4e-36 124.9 0.1 1.6 1 0 0 1 1 1 1 tRNA ligase kinase domain tRNA_lig_CPD PF08302.11 KXS10539.1 - 1.4e-31 109.9 0.0 2.2e-31 109.2 0.0 1.2 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain AAA_18 PF13238.6 KXS10539.1 - 0.0017 18.9 0.0 0.0044 17.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain TaqI_C PF12950.7 KXS10539.1 - 0.014 15.4 0.1 0.049 13.7 0.1 1.9 2 0 0 2 2 2 0 TaqI-like C-terminal specificity domain adh_short_C2 PF13561.6 KXS10540.1 - 2.3e-51 174.6 1.0 2.2e-50 171.4 1.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXS10540.1 - 2.8e-43 147.7 2.0 2.1e-42 144.8 2.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXS10540.1 - 4.8e-07 29.9 1.2 9.4e-07 28.9 1.2 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXS10540.1 - 2e-05 24.2 0.5 3.2e-05 23.5 0.5 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF664 PF04978.12 KXS10540.1 - 0.016 15.6 0.0 0.027 14.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF664) 3Beta_HSD PF01073.19 KXS10540.1 - 0.029 13.4 3.0 0.068 12.2 3.0 1.5 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family UDPG_MGDP_dh_N PF03721.14 KXS10540.1 - 0.11 12.1 2.1 0.14 11.7 1.1 1.7 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain OPT PF03169.15 KXS10541.1 - 1.2e-117 394.1 40.0 1.4e-117 393.9 40.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Phage_holin_5_2 PF16079.5 KXS10541.1 - 0.018 15.3 0.3 0.018 15.3 0.3 4.1 5 0 0 5 5 5 0 Phage holin family Hol44, in holin superfamily V CrgA PF06781.12 KXS10541.1 - 0.3 11.1 2.8 1.1 9.4 0.0 3.2 3 0 0 3 3 3 0 Cell division protein CrgA DUF4231 PF14015.6 KXS10541.1 - 1.3 9.5 4.3 0.46 11.0 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) DUF2306 PF10067.9 KXS10541.1 - 2.2 8.5 12.1 1.9 8.7 2.2 3.5 3 0 0 3 3 3 0 Predicted membrane protein (DUF2306) ABM PF03992.16 KXS10542.1 - 2.4e-21 75.6 0.1 2.6e-21 75.5 0.1 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Cyclase_polyket PF04673.12 KXS10542.1 - 0.094 13.0 0.0 0.12 12.6 0.0 1.1 1 0 0 1 1 1 0 Polyketide synthesis cyclase PhyH PF05721.13 KXS10543.1 - 2e-13 51.1 0.0 2.8e-08 34.3 0.0 2.0 1 1 1 2 2 2 2 Phytanoyl-CoA dioxygenase (PhyH) MFS_1 PF07690.16 KXS10544.1 - 0.0081 15.1 8.2 0.021 13.7 4.2 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Caveolin PF01146.17 KXS10544.1 - 0.65 10.0 4.1 11 6.0 1.9 2.2 1 1 1 2 2 2 0 Caveolin MFS_1 PF07690.16 KXS10545.1 - 4.5e-38 131.1 41.7 4.5e-38 131.1 41.7 1.6 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXS10545.1 - 8.3e-09 34.8 9.5 8.3e-09 34.8 9.5 3.0 3 0 0 3 3 3 1 Sugar (and other) transporter MFS_3 PF05977.13 KXS10545.1 - 0.0011 17.5 8.3 0.0016 16.9 8.3 1.3 1 0 0 1 1 1 1 Transmembrane secretion effector F-box-like PF12937.7 KXS10548.1 - 8.2e-10 38.4 1.2 1.6e-09 37.5 1.2 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXS10548.1 - 1.2e-06 28.2 1.3 2.3e-06 27.3 1.3 1.4 1 0 0 1 1 1 1 F-box domain PQQ_3 PF13570.6 KXS10548.1 - 0.023 15.2 1.2 13 6.4 0.1 3.2 2 0 0 2 2 2 0 PQQ-like domain MFS_1 PF07690.16 KXS10549.1 - 5e-15 55.3 62.3 1.1e-12 47.5 35.3 2.9 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.13 KXS10549.1 - 4e-05 22.3 15.2 0.00032 19.3 15.2 2.1 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Pyr_redox_2 PF07992.14 KXS10550.1 - 1.7e-37 129.3 0.0 2.1e-37 128.9 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXS10550.1 - 6.8e-13 49.0 1.4 6.4e-10 39.4 0.9 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXS10550.1 - 7.8e-10 38.5 0.0 1.6e-08 34.2 0.0 2.0 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXS10550.1 - 1.7e-09 37.7 0.5 0.068 12.7 0.0 3.3 3 0 0 3 3 3 3 FAD dependent oxidoreductase K_oxygenase PF13434.6 KXS10550.1 - 1.1e-05 24.7 0.1 2.3e-05 23.7 0.1 1.4 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.14 KXS10550.1 - 8.4e-05 21.6 0.8 0.6 8.9 0.2 3.1 2 1 1 3 3 3 2 Tryptophan halogenase Lycopene_cycl PF05834.12 KXS10550.1 - 0.0001 21.5 0.1 0.02 14.0 0.0 3.0 3 0 0 3 3 3 1 Lycopene cyclase protein Thi4 PF01946.17 KXS10550.1 - 0.00022 20.6 0.2 0.039 13.2 0.0 2.3 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 KXS10550.1 - 0.00072 18.7 0.1 0.15 11.1 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KXS10550.1 - 0.00075 19.7 0.4 1.2 9.4 0.2 2.8 2 1 0 2 2 2 2 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KXS10550.1 - 0.0013 18.7 1.3 0.33 10.9 0.0 3.2 2 1 1 3 3 3 1 FAD-NAD(P)-binding FAD_oxidored PF12831.7 KXS10550.1 - 0.0021 17.5 1.3 2.9 7.1 0.0 3.9 4 0 0 4 4 4 1 FAD dependent oxidoreductase Beta_helix_2 PF18835.1 KXS10550.1 - 0.009 15.7 0.1 0.03 14.1 0.1 1.8 1 0 0 1 1 1 1 Beta helix repeat of Inulin fructotransferase HI0933_like PF03486.14 KXS10550.1 - 0.017 13.8 0.9 1.4 7.6 0.2 3.1 2 1 1 3 3 3 0 HI0933-like protein GIDA PF01134.22 KXS10550.1 - 0.028 13.5 0.2 3.2 6.7 0.1 2.5 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_3 PF01494.19 KXS10550.1 - 0.053 12.8 0.1 0.52 9.5 0.1 2.1 2 0 0 2 2 2 0 FAD binding domain TrkA_N PF02254.18 KXS10550.1 - 0.18 12.1 0.9 0.49 10.7 0.2 2.1 2 0 0 2 2 2 0 TrkA-N domain PhyH PF05721.13 KXS10551.1 - 4.4e-50 170.9 0.0 5.5e-50 170.5 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 KXS10551.1 - 0.0075 16.7 0.0 0.019 15.4 0.0 1.7 2 0 0 2 2 2 1 Putative 2OG-Fe(II) oxygenase SH3_9 PF14604.6 KXS10552.1 - 7.2e-06 25.8 0.1 5.7e-05 22.9 0.0 2.3 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 KXS10552.1 - 0.00015 21.3 0.0 0.00089 18.8 0.0 2.3 3 0 0 3 3 3 1 SH3 domain Microvir_J PF04726.13 KXS10553.1 - 0.1 12.6 2.1 0.2 11.6 0.2 2.1 2 0 0 2 2 2 0 Microvirus J protein UvdE PF03851.14 KXS10554.1 - 2.6e-84 282.8 0.0 3.4e-84 282.4 0.0 1.1 1 0 0 1 1 1 1 UV-endonuclease UvdE Gal-3-0_sulfotr PF06990.11 KXS10554.1 - 0.018 14.0 0.1 0.5 9.2 0.0 2.1 2 0 0 2 2 2 0 Galactose-3-O-sulfotransferase DUF5381 PF17353.2 KXS10554.1 - 0.071 12.9 0.0 0.51 10.1 0.0 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5381) Tctex-1 PF03645.13 KXS10555.1 - 3.4e-26 91.5 0.0 4.3e-26 91.1 0.0 1.1 1 0 0 1 1 1 1 Tctex-1 family Ribonuclease_T2 PF00445.18 KXS10556.1 - 0.076 13.2 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 Ribonuclease T2 family COMM_domain PF07258.14 KXS10556.1 - 0.13 12.3 0.8 0.33 11.1 0.4 1.8 2 0 0 2 2 2 0 COMM domain Annexin PF00191.20 KXS10557.1 - 1.8e-72 239.4 4.4 1.3e-19 70.0 0.0 4.1 4 0 0 4 4 4 4 Annexin OST-HTH PF12872.7 KXS10557.1 - 0.0064 16.3 0.0 1.5 8.7 0.0 3.6 4 1 0 4 4 4 1 OST-HTH/LOTUS domain RNase_H_2 PF13482.6 KXS10557.1 - 0.0089 16.0 0.0 0.014 15.4 0.0 1.4 1 0 0 1 1 1 1 RNase_H superfamily PurK_C PF17769.1 KXS10557.1 - 0.077 12.7 0.3 2.3 8.0 0.0 2.6 3 0 0 3 3 3 0 Phosphoribosylaminoimidazole carboxylase C-terminal domain YlbE PF14003.6 KXS10557.1 - 0.1 13.0 0.1 20 5.7 0.1 3.4 3 0 0 3 3 3 0 YlbE-like protein DUF3198 PF11433.8 KXS10557.1 - 0.11 12.3 0.3 0.33 10.9 0.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3198) DUF1275 PF06912.11 KXS10558.1 - 0.0026 17.7 0.5 0.0041 17.1 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) NmrA PF05368.13 KXS10559.1 - 3.8e-35 121.5 0.0 4.8e-35 121.2 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXS10559.1 - 1.2e-20 74.2 0.0 1.9e-20 73.5 0.0 1.4 2 0 0 2 2 2 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KXS10559.1 - 1.4e-09 37.4 0.1 2.1e-09 36.8 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KXS10559.1 - 3.9e-07 29.8 0.0 7.4e-07 28.9 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KXS10559.1 - 0.00089 19.5 0.2 0.0018 18.6 0.2 1.5 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain AA_permease_2 PF13520.6 KXS10560.1 - 5.6e-45 153.9 51.9 7.6e-45 153.5 51.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXS10560.1 - 2.7e-15 55.9 46.9 3.7e-15 55.5 46.9 1.1 1 0 0 1 1 1 1 Amino acid permease Exo_endo_phos PF03372.23 KXS10562.1 - 0.00099 18.7 0.0 0.0014 18.2 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 KXS10562.1 - 0.018 14.8 0.0 0.28 11.1 0.0 2.2 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase Fungal_trans PF04082.18 KXS10565.1 - 1.2e-22 80.3 0.0 1.9e-22 79.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXS10565.1 - 1.3e-08 34.8 11.2 2.5e-08 33.9 11.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2826 PF11442.8 KXS10565.1 - 0.024 14.5 0.3 0.045 13.6 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2826) Prefoldin_2 PF01920.20 KXS10566.1 - 2.7e-16 59.4 1.6 3.2e-16 59.2 1.6 1.1 1 0 0 1 1 1 1 Prefoldin subunit Tab2_like PF06485.11 KXS10566.1 - 0.015 14.8 0.5 0.021 14.4 0.5 1.3 1 1 0 1 1 1 0 RNA-binding protein Tab2/Atab2 DNA_repr_REX1B PF14966.6 KXS10566.1 - 0.031 14.9 1.7 0.038 14.7 0.4 1.8 1 1 1 2 2 2 0 DNA repair REX1-B Chorismate_synt PF01264.21 KXS10566.1 - 0.034 12.9 0.0 0.04 12.6 0.0 1.1 1 0 0 1 1 1 0 Chorismate synthase zf-RanBP PF00641.18 KXS10567.1 - 2e-05 23.8 7.4 3.2e-05 23.1 7.4 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others RecR PF02132.15 KXS10567.1 - 0.44 10.1 2.9 0.84 9.3 2.9 1.4 1 0 0 1 1 1 0 RecR protein Thioredoxin PF00085.20 KXS10568.1 - 1.3e-49 166.5 0.0 3.6e-25 87.9 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_6 PF13848.6 KXS10568.1 - 3e-17 63.1 0.0 1.3e-10 41.5 0.0 3.1 2 1 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_2 PF13098.6 KXS10568.1 - 1e-10 42.0 0.2 1.9e-05 25.0 0.0 3.0 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KXS10568.1 - 2.7e-09 37.2 0.0 0.0015 18.8 0.0 4.6 3 2 1 4 4 4 2 Thioredoxin-like Thioredoxin_7 PF13899.6 KXS10568.1 - 1.4e-08 34.8 0.0 0.0008 19.5 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin-like TraF PF13728.6 KXS10568.1 - 3.2e-05 23.9 0.0 0.15 11.8 0.0 2.3 2 0 0 2 2 2 2 F plasmid transfer operon protein HyaE PF07449.11 KXS10568.1 - 8.8e-05 22.4 0.0 2.6 8.1 0.0 4.0 4 0 0 4 4 4 2 Hydrogenase-1 expression protein HyaE Thioredoxin_3 PF13192.6 KXS10568.1 - 0.00011 22.1 0.0 0.46 10.6 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin domain OST3_OST6 PF04756.13 KXS10568.1 - 0.00016 21.2 0.0 0.0092 15.4 0.0 2.9 3 1 0 3 3 3 1 OST3 / OST6 family, transporter family Thioredoxin_9 PF14595.6 KXS10568.1 - 0.0024 17.6 0.0 0.74 9.6 0.0 2.7 3 0 0 3 3 3 1 Thioredoxin Redoxin PF08534.10 KXS10568.1 - 0.019 14.7 0.3 1.6 8.5 0.1 2.5 2 0 0 2 2 2 0 Redoxin Asp_Glu_race_2 PF14669.6 KXS10568.1 - 0.16 11.6 0.0 0.33 10.6 0.0 1.4 1 0 0 1 1 1 0 Putative aspartate racemase zf-FPG_IleRS PF06827.14 KXS10568.1 - 0.24 11.3 4.8 1.5 8.8 0.5 2.5 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS DUF2934 PF11154.8 KXS10569.1 - 0.0069 16.0 0.9 0.012 15.2 0.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2934) Methyltransf_23 PF13489.6 KXS10570.1 - 1.4e-16 60.7 0.0 2.2e-16 60.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXS10570.1 - 1.1e-15 58.0 0.0 2.1e-15 57.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXS10570.1 - 7.1e-14 52.3 0.0 1.3e-13 51.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXS10570.1 - 2.6e-12 47.3 0.1 4.7e-12 46.5 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXS10570.1 - 5.9e-09 35.9 0.0 1e-08 35.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXS10570.1 - 1.1e-07 31.5 0.1 1.7e-07 30.8 0.1 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family DREV PF05219.12 KXS10570.1 - 1.2e-05 24.5 0.0 2.3e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 DREV methyltransferase MTS PF05175.14 KXS10570.1 - 0.015 14.9 0.0 0.023 14.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_PK PF05891.12 KXS10570.1 - 0.12 11.9 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Methyltransf_16 PF10294.9 KXS10570.1 - 0.14 11.9 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase ABC_tran PF00005.27 KXS10571.1 - 1.3e-50 171.5 0.1 7.6e-27 94.5 0.0 4.0 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KXS10571.1 - 9.7e-15 55.2 1.6 0.021 14.7 0.1 4.4 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system Chromo PF00385.24 KXS10571.1 - 4.1e-09 36.2 0.4 7.4e-09 35.4 0.4 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain SMC_N PF02463.19 KXS10571.1 - 1e-08 34.9 0.1 0.22 11.0 0.0 4.2 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KXS10571.1 - 1.3e-08 34.5 0.0 0.00084 19.0 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KXS10571.1 - 7e-08 32.6 0.3 0.00059 19.8 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KXS10571.1 - 3.2e-07 30.4 0.0 0.0044 17.1 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.6 KXS10571.1 - 5.2e-07 30.4 5.3 0.01 16.3 0.0 3.0 3 1 0 3 3 2 2 AAA domain AAA_22 PF13401.6 KXS10571.1 - 1.2e-05 25.5 1.0 0.19 12.0 0.0 3.6 5 0 0 5 5 2 2 AAA domain NACHT PF05729.12 KXS10571.1 - 3.7e-05 23.7 0.1 0.076 12.9 0.0 2.7 2 0 0 2 2 2 2 NACHT domain AAA_28 PF13521.6 KXS10571.1 - 4e-05 23.9 0.0 0.52 10.5 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.6 KXS10571.1 - 5.4e-05 23.6 0.1 0.47 10.8 0.0 3.1 3 0 0 3 3 3 2 AAA ATPase domain Rad17 PF03215.15 KXS10571.1 - 7.1e-05 22.8 0.1 0.037 14.0 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain DUF87 PF01935.17 KXS10571.1 - 7.5e-05 22.9 0.2 0.0057 16.8 0.0 2.8 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_33 PF13671.6 KXS10571.1 - 0.00016 21.9 0.1 1 9.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain NB-ARC PF00931.22 KXS10571.1 - 0.00031 20.0 0.1 0.035 13.3 0.0 2.6 3 0 0 3 3 2 1 NB-ARC domain RNA_helicase PF00910.22 KXS10571.1 - 0.00041 20.7 0.1 1.5 9.2 0.0 2.9 2 0 0 2 2 2 2 RNA helicase AAA_30 PF13604.6 KXS10571.1 - 0.00044 20.0 0.1 0.22 11.2 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 KXS10571.1 - 0.00063 19.6 0.0 0.27 10.9 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 KXS10571.1 - 0.00064 20.3 0.0 2 9.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_27 PF13514.6 KXS10571.1 - 0.00077 19.1 0.5 0.75 9.3 0.0 2.9 3 0 0 3 3 3 1 AAA domain MeaB PF03308.16 KXS10571.1 - 0.0011 18.0 0.8 0.18 10.8 0.1 2.5 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA PF00004.29 KXS10571.1 - 0.0013 19.2 0.0 3.7 8.0 0.0 3.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KXS10571.1 - 0.0016 18.2 0.0 1.1 8.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain FliH PF02108.16 KXS10571.1 - 0.0029 17.7 0.6 0.39 10.8 0.1 2.9 2 0 0 2 2 2 1 Flagellar assembly protein FliH ParcG PF10274.9 KXS10571.1 - 0.0096 16.1 1.8 0.094 12.8 0.3 2.3 1 1 1 2 2 2 1 Parkin co-regulated protein IstB_IS21 PF01695.17 KXS10571.1 - 0.012 15.4 0.2 9.5 5.9 0.0 3.7 4 0 0 4 4 4 0 IstB-like ATP binding protein Dynamin_N PF00350.23 KXS10571.1 - 0.013 15.6 0.1 4 7.5 0.0 3.1 2 1 1 3 3 3 0 Dynamin family AAA_14 PF13173.6 KXS10571.1 - 0.014 15.4 0.0 9.5 6.3 0.0 2.8 2 1 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 KXS10571.1 - 0.015 15.2 0.4 4.7 7.1 0.1 3.0 3 0 0 3 3 3 0 NTPase Roc PF08477.13 KXS10571.1 - 0.016 15.4 0.0 4.8 7.4 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Cytidylate_kin PF02224.18 KXS10571.1 - 0.016 14.9 0.1 3.2 7.4 0.0 2.5 2 0 0 2 2 2 0 Cytidylate kinase DUF815 PF05673.13 KXS10571.1 - 0.017 14.3 0.1 0.26 10.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) TsaE PF02367.17 KXS10571.1 - 0.023 14.7 0.5 4.2 7.4 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 KXS10571.1 - 0.04 13.5 0.2 13 5.2 0.0 3.0 3 0 0 3 3 3 0 AAA domain Ploopntkinase3 PF18751.1 KXS10571.1 - 0.04 13.8 0.0 26 4.7 0.0 3.4 4 0 0 4 4 4 0 P-loop Nucleotide Kinase3 AAA_7 PF12775.7 KXS10571.1 - 0.052 13.1 0.2 7.1 6.1 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region PduV-EutP PF10662.9 KXS10571.1 - 0.053 13.3 0.0 2.9 7.7 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Mg_chelatase PF01078.21 KXS10571.1 - 0.064 12.6 0.3 1 8.7 0.1 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI cobW PF02492.19 KXS10571.1 - 0.084 12.5 0.1 12 5.4 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ATPase_2 PF01637.18 KXS10571.1 - 0.089 12.7 0.1 17 5.2 0.0 2.8 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea AAA_13 PF13166.6 KXS10571.1 - 0.09 11.4 0.0 8.7 4.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 KXS10571.1 - 0.1 12.4 0.5 7.5 6.3 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_5 PF07728.14 KXS10571.1 - 0.19 11.7 0.5 17 5.4 0.0 2.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) MutS_V PF00488.21 KXS10571.1 - 0.23 11.5 0.7 8.5 6.3 0.2 2.3 2 0 0 2 2 2 0 MutS domain V DUF3584 PF12128.8 KXS10571.1 - 0.26 8.8 1.0 7.5 3.9 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Trypsin PF00089.26 KXS10572.1 - 1.2e-27 97.2 0.2 1.4e-27 97.0 0.2 1.1 1 0 0 1 1 1 1 Trypsin Gp_dh_C PF02800.20 KXS10573.1 - 1.6e-53 180.5 0.1 2.5e-53 179.9 0.1 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 KXS10573.1 - 8.7e-19 67.7 0.9 2.4e-17 63.1 0.0 2.8 3 0 0 3 3 3 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Trypsin PF00089.26 KXS10574.1 - 1.1e-28 100.6 0.6 1.3e-28 100.3 0.6 1.1 1 0 0 1 1 1 1 Trypsin HLH PF00010.26 KXS10576.1 - 4.3e-07 29.8 0.7 8e-07 28.9 0.7 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain NUDIX PF00293.28 KXS10577.1 - 4.4e-14 52.6 0.0 6.9e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Photo_RC PF00124.19 KXS10577.1 - 0.055 12.7 0.0 0.077 12.2 0.0 1.1 1 0 0 1 1 1 0 Photosynthetic reaction centre protein Glyco_hydro_31 PF01055.26 KXS10579.1 - 6.4e-40 137.7 0.3 2.7e-28 99.3 0.0 2.6 1 1 1 2 2 2 2 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 KXS10579.1 - 2.1e-07 31.1 0.0 3.7e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Fz PF01392.22 KXS10580.1 - 1.9e-06 28.5 2.5 4.2e-06 27.3 2.5 1.6 1 0 0 1 1 1 1 Fz domain Prefoldin_2 PF01920.20 KXS10580.1 - 0.032 14.2 0.6 0.078 12.9 0.6 1.6 1 0 0 1 1 1 0 Prefoldin subunit HalX PF08663.10 KXS10580.1 - 0.056 13.8 1.6 0.13 12.6 1.6 1.6 1 0 0 1 1 1 0 HalX domain DEC-1_N PF04625.13 KXS10580.1 - 1.1 8.2 10.0 1.7 7.5 10.0 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region LRR_4 PF12799.7 KXS10581.1 - 0.00012 22.3 7.4 0.43 11.1 0.2 6.1 6 1 1 7 7 7 2 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KXS10581.1 - 0.00013 21.8 0.0 0.00035 20.4 0.0 1.8 1 0 0 1 1 1 1 F-box-like SPC25 PF06703.11 KXS10583.1 - 2.7e-31 108.5 0.0 2.9e-30 105.2 0.0 2.1 1 1 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) NDK PF00334.19 KXS10584.1 - 4.4e-47 159.5 0.0 4.9e-47 159.3 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Ribosomal_S8 PF00410.19 KXS10586.1 - 2.9e-22 79.0 0.0 3.9e-22 78.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8 AAA PF00004.29 KXS10589.1 - 7.2e-15 55.6 0.1 8.4e-13 48.9 0.1 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BCS1_N PF08740.11 KXS10589.1 - 0.004 17.2 0.1 0.0063 16.5 0.1 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA_16 PF13191.6 KXS10589.1 - 0.008 16.6 0.2 0.053 13.9 0.1 2.4 1 1 1 2 2 2 1 AAA ATPase domain Bromo_TP PF07524.13 KXS10589.1 - 0.015 15.3 0.0 0.47 10.5 0.0 2.4 2 0 0 2 2 2 0 Bromodomain associated AAA_5 PF07728.14 KXS10589.1 - 0.032 14.2 0.0 5.6 7.0 0.0 2.3 1 1 1 2 2 2 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KXS10589.1 - 0.072 13.4 0.2 12 6.1 0.0 2.6 2 1 1 3 3 3 0 AAA domain adh_short PF00106.25 KXS10590.1 - 4.2e-57 192.8 1.4 5.4e-57 192.4 1.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXS10590.1 - 2.8e-41 141.6 0.7 3.3e-41 141.4 0.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXS10590.1 - 1.1e-16 61.2 0.1 1.5e-16 60.8 0.1 1.1 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 KXS10590.1 - 2.8e-05 24.4 0.4 4.3e-05 23.8 0.4 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 KXS10590.1 - 6.3e-05 22.5 0.1 9.7e-05 21.9 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KXS10590.1 - 0.00023 20.4 0.7 0.00037 19.7 0.7 1.3 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 2-Hacid_dh_C PF02826.19 KXS10590.1 - 0.00092 18.6 0.4 0.0027 17.1 0.4 1.7 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 KXS10590.1 - 0.0036 17.9 1.5 0.0081 16.7 0.6 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent THF_DHG_CYH_C PF02882.19 KXS10590.1 - 0.043 13.1 0.4 0.086 12.2 0.1 1.7 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Shikimate_DH PF01488.20 KXS10590.1 - 0.049 13.7 0.6 0.091 12.8 0.6 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase RmlD_sub_bind PF04321.17 KXS10590.1 - 0.096 11.8 1.1 0.13 11.3 1.1 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain NAD_binding_7 PF13241.6 KXS10590.1 - 0.18 12.3 1.8 0.4 11.1 1.8 1.6 1 1 0 1 1 1 0 Putative NAD(P)-binding 3HCDH_N PF02737.18 KXS10590.1 - 0.22 11.4 2.4 0.36 10.7 2.4 1.4 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain p450 PF00067.22 KXS10591.1 - 1.5e-69 234.9 0.0 2.1e-69 234.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FA_hydroxylase PF04116.13 KXS10592.1 - 1.6e-19 70.5 12.4 1.6e-19 70.5 12.4 1.7 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF1294 PF06961.13 KXS10592.1 - 0.035 14.3 0.4 11 6.4 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1294) Per1 PF04080.13 KXS10593.1 - 1.6e-89 300.0 7.8 1.4e-54 185.6 0.2 2.1 2 0 0 2 2 2 2 Per1-like family Fungal_trans PF04082.18 KXS10595.1 - 6.5e-14 51.6 0.1 1e-13 51.0 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXS10595.1 - 4.6e-10 39.4 11.6 8.4e-10 38.6 11.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Rnk_N PF14760.6 KXS10595.1 - 1.4 9.4 3.1 16 6.0 0.1 2.6 2 0 0 2 2 2 0 Rnk N-terminus Peptidase_S58 PF03576.14 KXS10596.1 - 0.011 15.3 0.0 0.013 15.1 0.0 1.0 1 0 0 1 1 1 0 Peptidase family S58 Peptidase_S58 PF03576.14 KXS10597.1 - 6.6e-69 232.7 0.9 7.4e-69 232.5 0.9 1.0 1 0 0 1 1 1 1 Peptidase family S58 BKACE PF05853.12 KXS10598.1 - 5e-44 150.7 0.0 7.1e-35 120.6 0.0 2.0 2 0 0 2 2 2 2 beta-keto acid cleavage enzyme Ribosomal_L23eN PF03939.13 KXS10599.1 - 0.76 10.0 4.4 0.42 10.8 0.5 2.2 2 0 0 2 2 2 0 Ribosomal protein L23, N-terminal domain F-box-like PF12937.7 KXS10600.1 - 0.0037 17.1 0.0 0.015 15.2 0.0 2.1 2 1 0 2 2 2 1 F-box-like LRR_6 PF13516.6 KXS10600.1 - 0.25 11.5 3.2 17 5.8 0.2 2.9 3 0 0 3 3 3 0 Leucine Rich repeat adh_short_C2 PF13561.6 KXS10601.1 - 4.7e-26 91.8 0.1 8.8e-16 58.2 0.0 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXS10601.1 - 1.7e-15 57.0 0.3 5.1e-09 35.9 0.0 2.2 1 1 1 2 2 2 2 short chain dehydrogenase MBOAT PF03062.19 KXS10602.1 - 4.4e-37 128.2 3.3 4.4e-37 128.2 3.3 2.0 2 1 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family NfI_DNAbd_pre-N PF10524.9 KXS10602.1 - 0.056 13.3 0.6 2.2 8.2 0.3 2.7 2 0 0 2 2 2 0 Nuclear factor I protein pre-N-terminus zf-C2H2 PF00096.26 KXS10603.1 - 0.00096 19.5 0.7 0.0029 18.0 0.7 1.9 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXS10603.1 - 0.0082 16.9 0.5 0.026 15.3 0.5 1.9 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2HC_2 PF13913.6 KXS10605.1 - 0.0022 17.8 2.8 0.0036 17.2 2.8 1.4 1 0 0 1 1 1 1 zinc-finger of a C2HC-type zf-C2H2 PF00096.26 KXS10605.1 - 0.016 15.6 0.2 0.028 14.9 0.2 1.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXS10605.1 - 0.046 14.6 0.2 0.084 13.8 0.2 1.4 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_4 PF13894.6 KXS10606.1 - 0.013 16.3 1.5 0.023 15.5 0.1 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KXS10606.1 - 0.12 12.4 0.0 0.12 12.4 0.0 2.0 2 0 0 2 2 2 0 C2H2-type zinc finger Dimer_Tnp_hAT PF05699.14 KXS10609.1 - 8.1e-11 41.6 0.0 2.6e-10 39.9 0.0 1.9 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DDE_Tnp_4 PF13359.6 KXS10610.1 - 5.1e-05 23.0 0.0 6.3e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Pro_dh PF01619.18 KXS10612.1 - 1.4e-60 205.4 0.0 2.5e-60 204.5 0.0 1.4 2 0 0 2 2 2 1 Proline dehydrogenase adh_short PF00106.25 KXS10613.1 - 1.2e-13 51.0 8.1 1.5e-13 50.7 8.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXS10613.1 - 8.9e-08 32.0 8.5 1.1e-07 31.7 8.5 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXS10613.1 - 0.00034 20.6 2.1 0.00041 20.3 0.8 1.8 2 0 0 2 2 2 1 KR domain Septin PF00735.18 KXS10614.1 - 2.3e-99 332.3 0.0 2.5e-99 332.1 0.0 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KXS10614.1 - 4.7e-07 29.9 0.0 1.3e-06 28.5 0.0 1.8 2 0 0 2 2 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KXS10614.1 - 1e-05 25.5 0.1 3.7e-05 23.7 0.1 1.8 2 0 0 2 2 2 1 RsgA GTPase T2SSE PF00437.20 KXS10614.1 - 1.5e-05 24.2 0.1 2.9e-05 23.3 0.0 1.5 2 0 0 2 2 1 1 Type II/IV secretion system protein Dynamin_N PF00350.23 KXS10614.1 - 5e-05 23.4 0.0 0.14 12.2 0.0 2.3 1 1 1 2 2 2 2 Dynamin family AIG1 PF04548.16 KXS10614.1 - 0.00026 20.4 0.0 0.00041 19.7 0.0 1.2 1 0 0 1 1 1 1 AIG1 family Roc PF08477.13 KXS10614.1 - 0.001 19.3 0.0 0.0017 18.6 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 KXS10614.1 - 0.0014 19.1 0.0 0.0023 18.5 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_7 PF12775.7 KXS10614.1 - 0.0018 17.9 0.0 0.0029 17.2 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region cobW PF02492.19 KXS10614.1 - 0.0023 17.5 0.2 0.0078 15.8 0.2 2.0 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain DUF815 PF05673.13 KXS10614.1 - 0.0031 16.7 0.0 0.0045 16.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 KXS10614.1 - 0.0031 17.8 0.1 0.009 16.3 0.1 1.9 1 1 0 1 1 1 1 AAA domain GTP_EFTU PF00009.27 KXS10614.1 - 0.0032 17.0 0.2 0.031 13.8 0.1 2.4 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_29 PF13555.6 KXS10614.1 - 0.0035 17.0 0.0 0.008 15.9 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain G-alpha PF00503.20 KXS10614.1 - 0.0036 16.5 0.0 0.0044 16.2 0.0 1.2 1 0 0 1 1 1 1 G-protein alpha subunit AAA_16 PF13191.6 KXS10614.1 - 0.0047 17.3 0.1 0.01 16.3 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain FtsK_SpoIIIE PF01580.18 KXS10614.1 - 0.0056 16.1 0.0 0.0094 15.3 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_33 PF13671.6 KXS10614.1 - 0.0061 16.7 0.2 0.014 15.6 0.2 1.6 1 1 0 1 1 1 1 AAA domain SRPRB PF09439.10 KXS10614.1 - 0.0086 15.5 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 KXS10614.1 - 0.0094 15.7 0.0 0.074 12.8 0.0 2.1 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.12 KXS10614.1 - 0.011 15.1 0.0 0.019 14.3 0.0 1.4 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.17 KXS10614.1 - 0.011 15.5 0.3 0.14 11.9 0.1 2.4 2 1 1 3 3 2 0 Conserved hypothetical ATP binding protein Mg_chelatase PF01078.21 KXS10614.1 - 0.012 15.0 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_23 PF13476.6 KXS10614.1 - 0.013 16.1 0.0 0.019 15.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KXS10614.1 - 0.014 15.4 0.0 0.025 14.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) SRP54 PF00448.22 KXS10614.1 - 0.02 14.5 0.3 0.07 12.8 0.2 1.9 2 1 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_21 PF13304.6 KXS10614.1 - 0.021 14.6 0.0 0.03 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Pox_A32 PF04665.12 KXS10614.1 - 0.026 14.0 0.0 0.045 13.2 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein TsaE PF02367.17 KXS10614.1 - 0.044 13.8 0.2 0.095 12.7 0.0 1.6 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 KXS10614.1 - 0.047 13.4 0.0 0.078 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KXS10614.1 - 0.063 12.8 0.0 0.13 11.8 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KXS10614.1 - 0.073 12.8 0.0 0.099 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 KXS10614.1 - 0.081 12.3 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein CLP1_P PF16575.5 KXS10614.1 - 0.083 12.7 0.0 12 5.6 0.0 2.3 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA PF00004.29 KXS10614.1 - 0.1 13.0 0.0 0.18 12.2 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KXS10614.1 - 0.13 12.7 0.0 0.22 11.9 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_28 PF13521.6 KXS10614.1 - 0.13 12.5 0.0 0.27 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KXS10614.1 - 0.17 11.1 0.0 0.31 10.2 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_14 PF13173.6 KXS10614.1 - 0.17 11.9 0.0 0.39 10.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain Rft-1 PF04506.13 KXS10615.1 - 0.11 11.2 0.1 0.16 10.7 0.1 1.2 1 0 0 1 1 1 0 Rft protein Astro_capsid_p PF12226.8 KXS10616.1 - 2 7.5 5.7 2.2 7.3 5.7 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein F-box-like PF12937.7 KXS10617.1 - 3.7e-05 23.5 0.6 0.0019 18.1 1.7 2.6 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KXS10617.1 - 0.17 11.8 0.9 1.2 9.0 1.5 2.1 2 0 0 2 2 2 0 F-box domain DUF3043 PF11241.8 KXS10617.1 - 10 6.2 8.5 2.3 8.2 0.7 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3043) Nop14 PF04147.12 KXS10618.1 - 2.1 6.5 18.9 3.1 5.9 18.9 1.2 1 0 0 1 1 1 0 Nop14-like family Zip PF02535.22 KXS10618.1 - 2.8 7.1 9.5 4 6.6 9.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter p450 PF00067.22 KXS10619.1 - 3.2e-23 82.2 0.1 1.2e-10 40.7 0.0 2.3 1 1 1 2 2 2 2 Cytochrome P450 DUF1684 PF07920.11 KXS10619.1 - 0.053 13.8 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1684) F-box PF00646.33 KXS10621.1 - 0.0018 18.1 1.2 0.0035 17.2 0.1 1.9 2 1 0 2 2 2 1 F-box domain Abhydrolase_1 PF00561.20 KXS10623.1 - 2.6e-10 40.4 0.0 3.4e-10 40.0 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXS10623.1 - 7.7e-10 39.7 0.7 1.1e-09 39.2 0.7 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXS10623.1 - 2.6e-05 23.6 0.0 9.7e-05 21.7 0.0 1.8 2 0 0 2 2 2 1 Serine aminopeptidase, S33 ArsA_HSP20 PF17886.1 KXS10624.1 - 0.033 13.7 0.0 0.055 13.0 0.0 1.3 1 0 0 1 1 1 0 HSP20-like domain found in ArsA Got1 PF04178.12 KXS10625.1 - 9.3e-25 87.2 6.7 1e-24 87.1 6.7 1.0 1 0 0 1 1 1 1 Got1/Sft2-like family PMT PF02366.18 KXS10626.1 - 3e-80 269.3 22.6 3e-80 269.3 22.6 1.6 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 KXS10626.1 - 4.1e-53 179.9 11.0 4.1e-53 179.9 11.0 2.8 2 1 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 KXS10626.1 - 1.6e-31 109.6 1.3 2.4e-31 109.1 1.3 1.2 1 0 0 1 1 1 1 MIR domain PMT_2 PF13231.6 KXS10626.1 - 0.011 16.0 15.4 0.011 16.0 15.4 3.2 2 1 1 3 3 3 0 Dolichyl-phosphate-mannose-protein mannosyltransferase ADIP PF11559.8 KXS10629.1 - 0.0021 18.1 7.6 0.0026 17.9 7.6 1.1 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding Spc7 PF08317.11 KXS10629.1 - 0.0042 16.0 7.5 0.0053 15.7 7.5 1.0 1 0 0 1 1 1 1 Spc7 kinetochore protein EzrA PF06160.12 KXS10629.1 - 0.0055 14.9 3.4 0.0064 14.7 3.4 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA FUSC PF04632.12 KXS10629.1 - 0.017 13.7 3.2 0.019 13.6 3.2 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family GvpL_GvpF PF06386.11 KXS10629.1 - 0.019 14.9 4.5 0.022 14.7 4.5 1.0 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF CorA PF01544.18 KXS10629.1 - 0.023 14.0 2.4 0.027 13.8 2.4 1.0 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein ISG65-75 PF11727.8 KXS10629.1 - 0.032 13.4 0.8 0.038 13.2 0.8 1.1 1 0 0 1 1 1 0 Invariant surface glycoprotein DUF3402 PF11882.8 KXS10629.1 - 0.057 12.5 1.4 0.064 12.4 1.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3402) Orbi_VP5 PF00901.17 KXS10629.1 - 0.058 11.8 0.4 0.065 11.6 0.4 1.0 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 FlaC_arch PF05377.11 KXS10629.1 - 0.063 13.7 0.5 7.7 7.0 0.0 2.4 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) TMF_DNA_bd PF12329.8 KXS10629.1 - 0.087 12.8 8.9 0.53 10.3 7.3 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding THOC7 PF05615.13 KXS10629.1 - 0.1 12.9 8.5 0.22 11.8 8.4 1.6 1 1 0 1 1 1 0 Tho complex subunit 7 ZapB PF06005.12 KXS10629.1 - 0.1 13.1 7.4 2.6 8.6 0.2 2.2 2 0 0 2 2 2 0 Cell division protein ZapB YabA PF06156.13 KXS10629.1 - 0.11 13.2 1.8 0.15 12.7 1.8 1.3 1 0 0 1 1 1 0 Initiation control protein YabA FAM76 PF16046.5 KXS10629.1 - 0.12 11.7 0.2 0.13 11.6 0.2 1.1 1 0 0 1 1 1 0 FAM76 protein DUF148 PF02520.17 KXS10629.1 - 0.15 12.1 2.6 0.24 11.5 0.7 1.9 1 1 1 2 2 2 0 Domain of unknown function DUF148 TMCO5 PF14992.6 KXS10629.1 - 0.25 10.9 5.7 0.3 10.6 5.7 1.0 1 0 0 1 1 1 0 TMCO5 family YkyA PF10368.9 KXS10629.1 - 0.26 10.9 6.8 1.2 8.8 0.7 2.0 1 1 1 2 2 2 0 Putative cell-wall binding lipoprotein XLF PF09302.11 KXS10629.1 - 0.26 11.4 3.1 0.74 10.0 1.4 1.9 1 1 1 2 2 2 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component Fzo_mitofusin PF04799.13 KXS10629.1 - 0.34 10.4 2.3 0.59 9.7 2.3 1.5 1 1 0 1 1 1 0 fzo-like conserved region Metal_resist PF13801.6 KXS10629.1 - 0.37 11.0 8.7 0.74 10.0 8.7 1.5 1 1 0 1 1 1 0 Heavy-metal resistance DivIC PF04977.15 KXS10629.1 - 0.43 10.4 6.7 1.2 8.9 0.1 2.4 1 1 1 2 2 2 0 Septum formation initiator Atg14 PF10186.9 KXS10629.1 - 0.5 9.4 3.9 0.54 9.3 3.9 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 SLATT_4 PF18186.1 KXS10629.1 - 0.62 9.7 6.8 0.59 9.7 4.7 1.8 1 1 1 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 4 APG6_N PF17675.1 KXS10629.1 - 0.76 10.3 12.4 1.2 9.6 12.3 1.4 1 1 0 1 1 1 0 Apg6 coiled-coil region Med4 PF10018.9 KXS10629.1 - 2.3 7.9 6.7 11 5.7 0.7 2.0 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 Alg6_Alg8 PF03155.15 KXS10630.1 - 1.5e-142 476.0 25.5 2.2e-142 475.5 25.5 1.2 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Zn_Tnp_IS1595 PF12760.7 KXS10631.1 - 0.13 12.3 3.1 8.7 6.4 0.6 2.2 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Lysyl_oxidase PF01186.17 KXS10632.1 - 1.6e-40 138.9 0.0 2.4e-40 138.4 0.0 1.2 1 0 0 1 1 1 1 Lysyl oxidase Peptidase_M14 PF00246.24 KXS10633.1 - 2e-70 237.9 0.1 2.6e-70 237.5 0.1 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase DUF2249 PF10006.9 KXS10633.1 - 0.16 11.8 0.0 0.4 10.6 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2249) TauD PF02668.16 KXS10634.1 - 1.9e-63 214.8 3.1 2.4e-63 214.4 3.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Carboxyl_trans PF01039.22 KXS10635.1 - 1.4e-143 479.1 0.0 2e-143 478.7 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain Peptidase_M48 PF01435.18 KXS10636.1 - 1.1e-24 87.3 0.0 3e-24 85.9 0.0 1.7 1 1 0 1 1 1 1 Peptidase family M48 DUF5345 PF17280.2 KXS10636.1 - 0.16 12.0 0.0 0.38 10.8 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5345) TatD_DNase PF01026.21 KXS10637.1 - 7.4e-45 153.3 0.0 9.9e-45 152.9 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase DUF934 PF06073.12 KXS10637.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF934) SH3_9 PF14604.6 KXS10638.1 - 4.7e-18 64.8 0.0 1.3e-08 34.5 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 KXS10638.1 - 1.2e-15 56.8 0.0 1.1e-08 34.6 0.0 2.4 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 KXS10638.1 - 1.1e-05 25.0 0.0 0.0013 18.4 0.0 2.4 2 0 0 2 2 2 1 Variant SH3 domain EphA2_TM PF14575.6 KXS10638.1 - 0.094 13.6 0.2 0.23 12.3 0.0 1.7 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain cEGF PF12662.7 KXS10638.1 - 0.4 10.7 2.4 1.1 9.2 2.4 1.8 1 0 0 1 1 1 0 Complement Clr-like EGF-like Ion_trans PF00520.31 KXS10639.1 - 4.6e-24 85.0 17.3 6.1e-24 84.6 17.3 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 KXS10639.1 - 4.5e-09 36.1 7.9 4.5e-09 36.1 7.9 2.2 2 0 0 2 2 2 1 Ion channel UPF0121 PF03661.13 KXS10639.1 - 0.15 11.4 3.0 0.085 12.2 0.6 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0121) Pkinase PF00069.25 KXS10640.1 - 0.00046 19.7 0.0 0.0011 18.4 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain zf-C2H2 PF00096.26 KXS10641.1 - 7.5e-17 60.8 5.3 1.1e-05 25.7 0.6 3.3 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KXS10641.1 - 2.6e-13 49.7 1.5 4.7e-08 33.1 0.0 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KXS10641.1 - 1.4e-11 44.2 5.4 0.01 16.6 0.6 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KXS10641.1 - 9.3e-05 22.6 1.3 2.3 8.6 0.0 3.3 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 KXS10641.1 - 0.0015 18.8 0.7 0.11 12.8 0.3 2.2 1 1 1 2 2 2 1 C2H2-type zinc ribbon zf-met PF12874.7 KXS10641.1 - 0.0016 18.7 3.0 1.1 9.8 0.0 3.4 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KXS10641.1 - 0.004 17.1 5.1 3.7 7.6 1.0 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 KXS10641.1 - 0.015 15.4 2.0 4.2 7.6 0.6 2.5 2 0 0 2 2 2 0 Zinc ribbon domain Rubredoxin_2 PF18073.1 KXS10641.1 - 0.08 12.7 5.0 4.4 7.1 0.5 2.6 2 0 0 2 2 2 0 Rubredoxin metal binding domain zf_UBZ PF18439.1 KXS10641.1 - 0.1 12.2 0.6 16 5.2 0.1 2.6 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger OrfB_Zn_ribbon PF07282.11 KXS10641.1 - 0.11 12.5 1.2 2.6 8.0 0.0 2.4 2 0 0 2 2 2 0 Putative transposase DNA-binding domain zf-C2H2_11 PF16622.5 KXS10641.1 - 0.28 11.0 1.9 9.1 6.1 0.1 3.0 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-LYAR PF08790.11 KXS10641.1 - 0.64 10.0 3.2 15 5.6 0.1 3.0 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger zf-BED PF02892.15 KXS10641.1 - 0.92 9.6 4.3 1.1 9.3 0.4 2.4 2 0 0 2 2 2 0 BED zinc finger DZR PF12773.7 KXS10641.1 - 4.8 7.3 6.7 13 5.9 6.7 1.7 1 1 0 1 1 1 0 Double zinc ribbon zf_C2H2_ZHX PF18387.1 KXS10641.1 - 5.2 6.8 5.4 1.1 9.0 1.0 2.1 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain NTPase_I-T PF01931.18 KXS10643.1 - 1.8e-18 66.9 0.3 4.9e-15 55.7 0.2 2.1 1 1 1 2 2 2 2 Protein of unknown function DUF84 DDE_3 PF13358.6 KXS10644.1 - 6.9e-09 35.6 0.0 1.6e-08 34.4 0.0 1.7 1 1 0 1 1 1 1 DDE superfamily endonuclease Peptidase_C14 PF00656.22 KXS10645.1 - 1.4e-51 175.8 0.1 2e-51 175.4 0.1 1.1 1 0 0 1 1 1 1 Caspase domain Pho88 PF10032.9 KXS10645.1 - 0.022 14.0 0.2 0.035 13.4 0.2 1.3 1 0 0 1 1 1 0 Phosphate transport (Pho88) Extensin_2 PF04554.13 KXS10645.1 - 0.4 10.8 10.8 0.96 9.6 10.8 1.6 1 0 0 1 1 1 0 Extensin-like region BAT2_N PF07001.11 KXS10645.1 - 1 9.8 11.4 6 7.3 1.8 2.7 2 0 0 2 2 2 0 BAT2 N-terminus GET2 PF08690.10 KXS10645.1 - 3.8 7.1 6.4 0.17 11.6 0.4 1.8 2 0 0 2 2 2 0 GET complex subunit GET2 Syntaxin-18_N PF10496.9 KXS10646.1 - 8.7e-11 41.9 0.0 2.2e-10 40.6 0.0 1.7 1 0 0 1 1 1 1 SNARE-complex protein Syntaxin-18 N-terminus DUF4201 PF13870.6 KXS10646.1 - 0.051 13.3 0.3 0.051 13.3 0.3 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) Abhydrolase_1 PF00561.20 KXS10649.1 - 2.9e-16 59.9 0.0 2.2e-15 57.0 0.0 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 KXS10649.1 - 3.1e-10 40.1 0.0 7.2e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein ATP_bind_2 PF03668.15 KXS10649.1 - 0.14 11.4 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 P-loop ATPase protein family Fib_alpha PF08702.10 KXS10650.1 - 0.089 13.0 1.1 13 5.9 0.0 3.5 4 0 0 4 4 4 0 Fibrinogen alpha/beta chain family HalX PF08663.10 KXS10650.1 - 0.34 11.3 2.6 4.4 7.7 0.0 3.0 2 1 0 2 2 2 0 HalX domain Fez1 PF06818.15 KXS10650.1 - 0.55 10.7 5.4 0.23 11.9 1.8 2.0 2 0 0 2 2 2 0 Fez1 NUP50 PF08911.11 KXS10652.1 - 0.33 11.7 1.5 0.42 11.3 1.0 1.6 1 1 0 1 1 1 0 NUP50 (Nucleoporin 50 kDa) Sel1 PF08238.12 KXS10655.1 - 6.1e-75 246.0 45.2 5e-10 39.7 1.5 10.4 10 0 0 10 10 10 9 Sel1 repeat Pkinase_Tyr PF07714.17 KXS10655.1 - 3.5e-35 121.5 0.0 1.3e-22 80.3 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXS10655.1 - 3.3e-33 115.2 0.0 8.5e-33 113.8 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KXS10655.1 - 0.00054 18.9 0.0 0.00089 18.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KXS10655.1 - 0.12 11.7 0.1 0.43 9.9 0.1 1.7 1 1 0 1 1 1 0 Kinase-like MFS_1 PF07690.16 KXS10656.1 - 3.7e-17 62.3 46.8 2.4e-10 39.9 21.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXS10656.1 - 7e-07 28.5 16.0 0.0036 16.2 10.5 2.4 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.6 KXS10656.1 - 0.01 14.4 31.9 0.0097 14.5 16.5 2.8 2 1 1 3 3 3 0 MFS/sugar transport protein CAAD PF14159.6 KXS10656.1 - 0.17 11.7 9.3 0.42 10.5 1.2 3.2 2 0 0 2 2 2 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase Aldo_ket_red PF00248.21 KXS10657.1 - 1.1e-36 126.5 0.0 1.5e-36 126.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family SH3_9 PF14604.6 KXS10659.1 - 4.3e-06 26.5 0.0 9.3e-06 25.4 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXS10659.1 - 2.1e-05 24.0 0.0 3.5e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 SH3 domain HHH_3 PF12836.7 KXS10659.1 - 0.16 12.3 0.1 0.29 11.4 0.1 1.4 1 0 0 1 1 1 0 Helix-hairpin-helix motif SHOCT PF09851.9 KXS10659.1 - 0.21 11.4 0.2 0.38 10.6 0.2 1.4 1 0 0 1 1 1 0 Short C-terminal domain Endonuclease_5 PF04493.14 KXS10660.1 - 1.8e-54 184.4 0.0 1e-53 182.0 0.0 2.0 1 1 0 1 1 1 1 Endonuclease V UvrC_HhH_N PF08459.11 KXS10660.1 - 0.17 11.8 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 UvrC Helix-hairpin-helix N-terminal Ribosomal_S27e PF01667.17 KXS10661.1 - 8.4e-26 89.5 1.7 8.4e-26 89.5 1.7 1.4 2 0 0 2 2 2 1 Ribosomal protein S27 zinc_ribbon_4 PF13717.6 KXS10661.1 - 0.021 14.7 2.9 1.1 9.3 0.5 2.4 2 0 0 2 2 2 0 zinc-ribbon domain DUF3797 PF12677.7 KXS10661.1 - 0.036 14.0 0.1 5.4 7.0 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3797) Mu-like_Com PF10122.9 KXS10661.1 - 0.11 12.0 4.2 1.6 8.3 0.1 2.2 1 1 1 2 2 2 0 Mu-like prophage protein Com Prok-RING_1 PF14446.6 KXS10661.1 - 0.48 10.4 3.6 1 9.4 3.6 1.5 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 DUF2162 PF09930.9 KXS10661.1 - 1.3 8.4 6.9 2.3 7.6 0.1 2.0 1 1 1 2 2 2 0 Predicted transporter (DUF2162) zf-LITAF-like PF10601.9 KXS10662.1 - 1.3e-16 60.6 0.8 2.1e-16 59.9 0.8 1.3 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain zf_UBZ PF18439.1 KXS10662.1 - 0.15 11.6 3.8 3.4 7.4 0.1 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_2 PF13240.6 KXS10662.1 - 0.21 11.4 3.1 6.5 6.6 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain HscB_4_cys PF18256.1 KXS10662.1 - 0.21 11.4 0.0 0.21 11.4 0.0 3.1 3 0 0 3 3 3 0 Co-chaperone HscB tetracysteine metal binding motif zf-C4_Topoisom PF01396.19 KXS10662.1 - 0.43 10.4 3.5 12 5.7 0.9 2.3 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger zf_C2H2_10 PF18414.1 KXS10662.1 - 0.44 10.1 5.0 2.3 7.8 0.9 2.3 2 0 0 2 2 2 0 C2H2 type zinc-finger UPF0547 PF10571.9 KXS10662.1 - 0.71 10.0 9.1 0.52 10.4 0.5 2.7 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 zf-Di19 PF05605.12 KXS10662.1 - 1.8 8.9 5.9 23 5.4 0.1 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-LITAF-like PF10601.9 KXS10663.1 - 1.9e-18 66.5 0.4 2.5e-18 66.1 0.4 1.1 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain Mut7-C PF01927.16 KXS10663.1 - 0.033 14.3 0.0 0.043 13.9 0.0 1.1 1 0 0 1 1 1 0 Mut7-C RNAse domain zf-LITAF-like PF10601.9 KXS10664.1 - 1.9e-19 69.7 1.3 2.6e-19 69.2 1.3 1.2 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain LPD22 PF18834.1 KXS10664.1 - 0.015 15.5 1.6 0.88 9.8 0.7 2.1 2 0 0 2 2 2 0 Large polyvalent protein associated domain 22 zf-C2HC5 PF06221.13 KXS10664.1 - 0.04 13.9 0.3 3.5 7.7 0.1 2.2 2 0 0 2 2 2 0 Putative zinc finger motif, C2HC5-type zinc_ribbon_2 PF13240.6 KXS10664.1 - 0.13 12.1 2.6 4.4 7.2 0.3 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-RING_7 PF02591.15 KXS10664.1 - 0.19 11.9 1.7 11 6.2 0.0 2.6 2 0 0 2 2 2 0 C4-type zinc ribbon domain RecR PF02132.15 KXS10664.1 - 2.6 7.7 4.8 3.5 7.3 0.6 2.1 2 0 0 2 2 2 0 RecR protein adh_short PF00106.25 KXS10666.1 - 1.6e-26 92.9 0.0 5.9e-22 78.1 0.0 2.0 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXS10666.1 - 6.1e-12 45.6 0.0 1.9e-11 44.0 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXS10666.1 - 4.3e-05 23.5 0.0 6.7e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXS10666.1 - 9.2e-05 22.0 0.1 0.002 17.7 0.1 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Glyco_transf_4 PF13439.6 KXS10666.1 - 0.0016 18.5 0.1 0.44 10.5 0.0 2.4 2 0 0 2 2 2 2 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 KXS10666.1 - 0.0048 17.3 0.2 0.071 13.6 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Ank_2 PF12796.7 KXS10667.1 - 2.5e-10 40.8 0.0 3.1e-05 24.5 0.0 2.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXS10667.1 - 2.6e-06 27.9 0.0 0.38 11.4 0.0 3.9 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXS10667.1 - 5.2e-05 23.4 0.1 1.3 9.4 0.0 4.1 5 0 0 5 5 5 2 Ankyrin repeats (many copies) Ank PF00023.30 KXS10667.1 - 0.00012 22.3 1.9 0.71 10.4 0.4 3.9 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 KXS10667.1 - 0.00059 20.1 0.9 19 6.2 0.0 5.0 5 1 0 5 5 5 1 Ankyrin repeat Glyoxalase PF00903.25 KXS10669.1 - 2.2e-10 40.8 0.0 4.5e-07 30.1 0.0 2.1 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KXS10669.1 - 0.00023 21.4 0.0 0.00033 20.9 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 KXS10669.1 - 0.002 18.3 0.0 0.0034 17.5 0.0 1.4 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_6 PF18029.1 KXS10669.1 - 0.0054 17.5 0.2 0.043 14.6 0.2 2.1 1 1 0 1 1 1 1 Glyoxalase-like domain PriCT_2 PF08707.11 KXS10670.1 - 5.5e-07 29.9 0.1 1.2e-06 28.7 0.1 1.6 1 0 0 1 1 1 1 Primase C terminal 2 (PriCT-2) Herpes_ori_bp PF02399.15 KXS10670.1 - 0.024 12.7 0.1 3.1 5.7 0.3 2.8 1 1 1 2 2 2 0 Origin of replication binding protein AAA_22 PF13401.6 KXS10670.1 - 0.092 13.0 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF726 PF05277.12 KXS10671.1 - 0.007 15.3 0.0 0.01 14.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) DUF726 PF05277.12 KXS10672.1 - 1.5e-80 270.7 0.0 2e-80 270.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Say1_Mug180 PF10340.9 KXS10672.1 - 0.046 12.6 0.4 0.42 9.4 0.4 2.0 1 1 0 1 1 1 0 Steryl acetyl hydrolase LCAT PF02450.15 KXS10672.1 - 0.13 11.4 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase LRIF1 PF15741.5 KXS10672.1 - 0.37 9.3 3.7 0.5 8.8 3.7 1.0 1 0 0 1 1 1 0 Ligand-dependent nuclear receptor-interacting factor 1 ANAPC_CDC26 PF10471.9 KXS10672.1 - 0.47 11.3 3.3 0.86 10.5 3.3 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit CDC26 Glyoxalase PF00903.25 KXS10673.1 - 3.7e-09 36.9 0.0 5e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily adh_short_C2 PF13561.6 KXS10674.1 - 2.2e-43 148.5 3.7 2.5e-43 148.3 3.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXS10674.1 - 1.9e-31 109.0 1.7 2.5e-31 108.7 1.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXS10674.1 - 6.5e-07 29.4 2.7 1.7e-05 24.8 0.1 2.1 2 0 0 2 2 2 2 KR domain YjeF_N PF03853.15 KXS10674.1 - 8.6e-05 22.5 0.1 0.00017 21.6 0.1 1.5 1 0 0 1 1 1 1 YjeF-related protein N-terminus HlyD_D23 PF16576.5 KXS10674.1 - 0.0071 15.6 0.1 0.011 15.0 0.1 1.2 1 0 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion Usp PF00582.26 KXS10675.1 - 0.0005 20.6 0.0 0.0018 18.8 0.0 2.0 1 1 0 1 1 1 1 Universal stress protein family YabA PF06156.13 KXS10675.1 - 0.029 15.0 0.0 0.046 14.4 0.0 1.3 1 0 0 1 1 1 0 Initiation control protein YabA PLDc_2 PF13091.6 KXS10676.1 - 1.9e-50 170.2 0.0 1.7e-24 86.2 0.0 2.4 2 1 0 2 2 2 2 PLD-like domain FAM83 PF07894.12 KXS10676.1 - 1.9e-12 47.3 1.1 0.00044 19.9 0.0 3.7 4 0 0 4 4 4 3 FAM83 A-H PLDc PF00614.22 KXS10676.1 - 0.0027 17.8 0.3 0.61 10.4 0.2 3.1 3 0 0 3 3 3 1 Phospholipase D Active site motif Regulator_TrmB PF11495.8 KXS10676.1 - 0.051 12.7 0.1 1.3 8.1 0.0 2.3 2 0 0 2 2 2 0 Archaeal transcriptional regulator TrmB 120_Rick_ant PF12574.8 KXS10676.1 - 0.11 11.7 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 120 KDa Rickettsia surface antigen NYN PF01936.18 KXS10676.1 - 0.16 12.4 0.1 0.49 10.9 0.0 1.8 2 0 0 2 2 2 0 NYN domain ParBc PF02195.18 KXS10677.1 - 0.013 15.8 0.1 0.043 14.1 0.0 1.9 2 0 0 2 2 2 0 ParB-like nuclease domain SARAF PF06682.12 KXS10677.1 - 0.037 13.7 1.1 0.2 11.3 0.0 2.0 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis Hist_deacetyl PF00850.19 KXS10678.1 - 5.7e-19 68.7 0.0 7e-19 68.4 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Response_reg PF00072.24 KXS10680.1 - 9.4e-20 70.9 0.4 1.6e-19 70.1 0.4 1.4 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 KXS10680.1 - 0.00014 21.8 1.2 0.0003 20.7 0.2 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c PF02518.26 KXS10680.1 - 0.015 15.8 0.0 0.073 13.6 0.0 2.0 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase BAF PF02961.14 KXS10680.1 - 0.19 12.2 0.0 0.38 11.2 0.0 1.5 1 0 0 1 1 1 0 Barrier to autointegration factor Syntaxin_2 PF14523.6 KXS10681.1 - 2e-19 69.8 9.2 6.3e-18 65.0 4.5 2.2 2 0 0 2 2 2 2 Syntaxin-like protein SNARE PF05739.19 KXS10681.1 - 1e-13 51.0 2.9 1.6e-13 50.5 1.2 2.1 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.25 KXS10681.1 - 0.00011 22.0 9.2 0.00023 20.9 9.2 1.6 1 1 0 1 1 1 1 Syntaxin MCPsignal PF00015.21 KXS10681.1 - 0.02 14.7 2.9 0.02 14.7 2.9 2.1 1 1 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Vac14_Fig4_bd PF11916.8 KXS10681.1 - 0.023 14.3 2.0 0.32 10.7 0.1 2.2 2 0 0 2 2 2 0 Vacuolar protein 14 C-terminal Fig4p binding Trimer_CC PF08954.11 KXS10681.1 - 0.1 12.2 1.5 0.61 9.7 0.0 3.0 3 1 1 4 4 4 0 Trimerisation motif DUF1664 PF07889.12 KXS10681.1 - 0.77 9.8 9.5 0.26 11.3 1.4 3.0 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF4404 PF14357.6 KXS10681.1 - 3.1 8.5 8.1 19 6.0 0.7 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4404) UPF0242 PF06785.11 KXS10681.1 - 5 7.2 10.3 40 4.3 10.3 2.1 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus SlyX PF04102.12 KXS10681.1 - 9.4 6.9 9.6 1.7 9.3 0.8 3.2 3 0 0 3 3 3 0 SlyX Use1 PF09753.9 KXS10682.1 - 6.3e-13 49.0 2.6 6.7e-13 48.9 2.6 1.0 1 0 0 1 1 1 1 Membrane fusion protein Use1 DUF2951 PF11166.8 KXS10682.1 - 0.053 13.7 0.0 0.065 13.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) BatD PF13584.6 KXS10682.1 - 0.054 12.3 0.2 0.057 12.2 0.2 1.0 1 0 0 1 1 1 0 Oxygen tolerance DASH_Dam1 PF08653.10 KXS10682.1 - 0.14 12.0 0.5 0.35 10.7 0.1 1.8 1 1 1 2 2 2 0 DASH complex subunit Dam1 FeoB_Cyto PF17910.1 KXS10682.1 - 0.18 12.4 0.0 0.23 12.1 0.0 1.1 1 0 0 1 1 1 0 FeoB cytosolic helical domain Med22 PF06179.12 KXS10683.1 - 2.5e-12 46.9 2.0 3.2e-12 46.6 2.0 1.2 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex AIP3 PF03915.13 KXS10683.1 - 0.0077 15.4 0.4 0.0088 15.2 0.4 1.0 1 0 0 1 1 1 1 Actin interacting protein 3 GIT_CC PF16559.5 KXS10683.1 - 0.042 13.7 0.1 0.07 13.0 0.1 1.4 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor ETC_C1_NDUFA5 PF04716.14 KXS10683.1 - 0.048 13.5 0.9 0.46 10.3 0.6 2.2 2 0 0 2 2 2 0 ETC complex I subunit conserved region Cnd2 PF05786.14 KXS10684.1 - 9.3e-18 64.3 0.3 1.1e-17 64.1 0.3 1.0 1 0 0 1 1 1 1 Condensin complex subunit 2 Cnd2 PF05786.14 KXS10685.1 - 1.3e-23 83.7 4.2 3.3e-18 65.8 0.8 2.2 1 1 0 2 2 2 2 Condensin complex subunit 2 PRA-CH PF01502.18 KXS10686.1 - 8.9e-20 70.3 0.0 1.5e-19 69.6 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.17 KXS10686.1 - 2.5e-14 53.5 0.0 4.6e-14 52.6 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase MazG-like PF12643.7 KXS10686.1 - 0.064 13.5 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 MazG-like family PAP_central PF04928.17 KXS10687.1 - 1.3e-111 371.6 0.0 1.6e-111 371.2 0.0 1.1 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 KXS10687.1 - 1.7e-36 125.5 0.1 1.8e-34 118.8 0.1 2.3 1 1 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 KXS10687.1 - 1.3e-10 41.4 0.0 3.7e-10 40.0 0.0 1.8 1 0 0 1 1 1 1 Nucleotidyltransferase domain Nrap_D2 PF17403.2 KXS10687.1 - 0.0046 16.7 0.0 0.0086 15.9 0.0 1.5 1 0 0 1 1 1 1 Nrap protein PAP/OAS-like domain Sel1 PF08238.12 KXS10688.1 - 8.2e-110 356.8 52.7 1.6e-09 38.1 0.5 16.1 16 0 0 16 16 16 16 Sel1 repeat Scm3 PF10384.9 KXS10689.1 - 4.7e-12 45.4 0.3 9.6e-12 44.5 0.3 1.5 1 0 0 1 1 1 1 Centromere protein Scm3 Complex1_LYR_2 PF13233.6 KXS10690.1 - 7.7e-14 52.2 0.1 1e-13 51.8 0.1 1.2 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 KXS10690.1 - 4e-06 26.8 0.2 6.5e-06 26.1 0.2 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) ChaB PF06150.12 KXS10690.1 - 0.021 15.4 0.5 0.096 13.3 0.2 2.1 2 0 0 2 2 2 0 ChaB CH PF00307.31 KXS10691.1 - 2e-13 50.5 0.0 1.8e-06 28.1 0.0 2.9 2 1 0 2 2 2 2 Calponin homology (CH) domain Myosin_head PF00063.21 KXS10692.1 - 3.5e-213 709.6 0.0 4.2e-213 709.4 0.0 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) AAA_16 PF13191.6 KXS10692.1 - 0.0011 19.3 0.0 0.0037 17.7 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KXS10692.1 - 0.02 15.2 0.0 0.051 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 KXS10692.1 - 0.069 12.2 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_19 PF13245.6 KXS10692.1 - 0.14 12.5 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain PI3_PI4_kinase PF00454.27 KXS10694.1 - 1.5e-37 129.8 0.0 7.8e-35 120.9 0.0 3.0 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 KXS10694.1 - 7.2e-21 74.4 0.0 1.5e-20 73.3 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) MKT1_C PF12246.8 KXS10694.1 - 0.074 12.3 0.3 0.18 11.0 0.0 1.7 2 0 0 2 2 2 0 Temperature dependent protein affecting M2 dsRNA replication DUF4135 PF13575.6 KXS10694.1 - 0.11 11.8 0.0 0.3 10.4 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4135) Sedlin_N PF04628.13 KXS10695.1 - 1.5e-48 164.3 0.0 1.6e-48 164.1 0.0 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 KXS10695.1 - 1e-08 35.2 0.1 1.5e-08 34.7 0.1 1.4 1 1 0 1 1 1 1 Sybindin-like family SURF6 PF04935.12 KXS10696.1 - 1.7e-34 119.4 27.9 1.7e-34 119.4 27.9 2.9 2 1 1 3 3 3 1 Surfeit locus protein 6 RRP14 PF15459.6 KXS10696.1 - 2.6e-21 76.0 1.4 2.6e-21 76.0 1.4 5.5 4 1 0 5 5 5 1 60S ribosome biogenesis protein Rrp14 MerR-DNA-bind PF09278.11 KXS10696.1 - 0.088 13.3 3.6 11 6.6 0.0 3.8 3 0 0 3 3 3 0 MerR, DNA binding SNF2_N PF00176.23 KXS10697.1 - 9.5e-23 80.5 0.1 2.9e-22 78.9 0.1 1.8 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KXS10697.1 - 1.3e-07 31.9 0.0 2.6e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 KXS10697.1 - 0.00039 19.7 0.3 0.0013 17.9 0.0 2.0 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.15 KXS10697.1 - 0.13 12.3 0.0 0.35 10.8 0.0 1.8 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit SH3_1 PF00018.28 KXS10698.1 - 0.0001 21.8 0.0 0.00017 21.1 0.0 1.4 1 0 0 1 1 1 1 SH3 domain Tropomyosin PF00261.20 KXS10698.1 - 0.00042 19.8 1.6 0.0007 19.0 1.6 1.3 1 0 0 1 1 1 1 Tropomyosin SH3_9 PF14604.6 KXS10698.1 - 0.00064 19.5 0.0 0.001 18.9 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain ATG16 PF08614.11 KXS10698.1 - 0.0012 19.1 5.5 0.0012 19.1 5.5 1.4 2 0 0 2 2 1 1 Autophagy protein 16 (ATG16) FlxA PF14282.6 KXS10698.1 - 0.0037 17.2 5.1 0.0065 16.4 5.1 1.3 1 0 0 1 1 1 1 FlxA-like protein TSC22 PF01166.18 KXS10698.1 - 0.0043 17.3 0.1 0.0092 16.3 0.1 1.5 1 0 0 1 1 1 1 TSC-22/dip/bun family PspA_IM30 PF04012.12 KXS10698.1 - 0.0051 16.4 5.3 0.007 16.0 5.3 1.1 1 0 0 1 1 1 1 PspA/IM30 family Uso1_p115_C PF04871.13 KXS10698.1 - 0.0058 17.0 3.8 0.0087 16.4 3.8 1.2 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, C terminal region Tropomyosin_1 PF12718.7 KXS10698.1 - 0.0086 16.2 0.6 0.012 15.7 0.6 1.2 1 0 0 1 1 1 1 Tropomyosin like Filament PF00038.21 KXS10698.1 - 0.0096 15.5 2.5 0.012 15.2 2.5 1.1 1 0 0 1 1 1 1 Intermediate filament protein CLZ PF16526.5 KXS10698.1 - 0.013 15.8 0.7 0.022 15.1 0.7 1.4 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ASD2 PF08687.11 KXS10698.1 - 0.016 14.7 0.1 0.023 14.3 0.1 1.1 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 MscS_porin PF12795.7 KXS10698.1 - 0.018 14.6 8.7 0.026 14.1 8.7 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain HOOK PF05622.12 KXS10698.1 - 0.024 12.8 0.3 0.029 12.6 0.3 1.0 1 0 0 1 1 1 0 HOOK protein DUF4686 PF15742.5 KXS10698.1 - 0.026 13.7 1.0 0.035 13.3 1.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4686) DUF724 PF05266.14 KXS10698.1 - 0.037 13.9 1.1 0.049 13.4 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) ADIP PF11559.8 KXS10698.1 - 0.043 13.9 2.6 0.068 13.3 2.6 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding bZIP_2 PF07716.15 KXS10698.1 - 0.054 13.6 1.7 0.11 12.6 1.7 1.5 1 0 0 1 1 1 0 Basic region leucine zipper APG6_N PF17675.1 KXS10698.1 - 0.067 13.7 2.8 0.098 13.2 2.8 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region PRKG1_interact PF15898.5 KXS10698.1 - 0.094 13.6 1.7 0.16 12.9 1.7 1.3 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain FlaC_arch PF05377.11 KXS10698.1 - 0.11 13.0 0.4 0.21 12.0 0.4 1.5 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) ABC_tran_CTD PF16326.5 KXS10698.1 - 0.12 12.7 5.4 0.1 12.9 0.9 2.1 2 0 0 2 2 2 0 ABC transporter C-terminal domain MerR-DNA-bind PF09278.11 KXS10698.1 - 0.13 12.8 2.6 0.31 11.6 2.6 1.6 1 0 0 1 1 1 0 MerR, DNA binding Nsp1_C PF05064.13 KXS10698.1 - 0.14 12.0 0.5 0.21 11.4 0.5 1.2 1 0 0 1 1 1 0 Nsp1-like C-terminal region Ax_dynein_light PF10211.9 KXS10698.1 - 0.14 12.1 0.8 0.2 11.6 0.8 1.2 1 0 0 1 1 1 0 Axonemal dynein light chain GAS PF13851.6 KXS10698.1 - 0.15 11.4 1.5 0.21 10.9 1.5 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding SlyX PF04102.12 KXS10698.1 - 0.16 12.6 2.1 0.36 11.5 1.7 1.8 1 1 1 2 2 1 0 SlyX CCDC53 PF10152.9 KXS10698.1 - 0.21 12.0 0.1 0.21 12.0 0.1 2.2 1 1 1 2 2 2 0 Subunit CCDC53 of WASH complex XhlA PF10779.9 KXS10698.1 - 0.25 11.6 0.2 0.42 10.8 0.2 1.3 1 0 0 1 1 1 0 Haemolysin XhlA ZapB PF06005.12 KXS10698.1 - 0.26 11.7 3.7 0.33 11.4 2.9 1.5 1 1 0 1 1 1 0 Cell division protein ZapB DUF4140 PF13600.6 KXS10698.1 - 0.33 11.4 9.5 4.2 7.9 9.5 2.2 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Cep57_CLD PF14073.6 KXS10698.1 - 0.34 10.9 5.6 0.78 9.7 5.6 1.5 1 1 0 1 1 1 0 Centrosome localisation domain of Cep57 DUF4200 PF13863.6 KXS10698.1 - 0.37 11.2 3.8 0.55 10.6 3.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Swi5 PF07061.11 KXS10698.1 - 0.41 10.8 3.2 0.45 10.6 1.2 1.9 1 1 1 2 2 2 0 Swi5 M PF02370.16 KXS10698.1 - 0.59 10.9 3.2 1.2 9.9 1.3 2.1 1 1 1 2 2 2 0 M protein repeat DUF3450 PF11932.8 KXS10698.1 - 0.93 8.7 6.9 1.3 8.2 6.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) TMF_DNA_bd PF12329.8 KXS10698.1 - 1.1 9.3 5.1 1.4 8.9 4.0 1.7 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding LPP PF04728.13 KXS10698.1 - 1.3 9.4 8.2 0.5 10.8 0.6 2.3 2 0 0 2 2 2 0 Lipoprotein leucine-zipper Alanine_zipper PF11839.8 KXS10698.1 - 1.8 9.0 19.2 3.9 7.9 2.9 2.3 1 1 1 2 2 2 0 Alanine-zipper, major outer membrane lipoprotein DivIC PF04977.15 KXS10698.1 - 6 6.7 6.4 1.2 9.0 2.9 1.5 2 0 0 2 2 1 0 Septum formation initiator IMUP PF15761.5 KXS10698.1 - 9.6 7.0 9.8 0.23 12.2 2.8 1.8 2 0 0 2 2 1 0 Immortalisation up-regulated protein DUF4964 PF16334.5 KXS10699.1 - 0.062 12.8 0.0 0.074 12.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4964) F-box-like PF12937.7 KXS10702.1 - 4.3e-06 26.5 0.3 1.3e-05 25.0 0.3 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXS10702.1 - 6e-06 26.0 0.5 1.6e-05 24.6 0.5 1.8 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KXS10702.1 - 0.0075 16.1 0.0 0.015 15.1 0.0 1.6 1 0 0 1 1 1 1 F-box FAD_binding_3 PF01494.19 KXS10703.1 - 9.5e-43 146.8 0.1 3.1e-34 118.8 0.0 2.2 1 1 1 2 2 2 2 FAD binding domain FAD_binding_2 PF00890.24 KXS10703.1 - 0.027 13.5 0.1 0.052 12.6 0.1 1.5 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.7 KXS10703.1 - 0.052 12.9 0.3 0.079 12.3 0.3 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXS10703.1 - 0.058 12.6 2.9 0.11 11.7 0.3 2.3 2 1 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Ncstrn_small PF18266.1 KXS10704.1 - 1.5e-33 116.1 0.0 6.8e-33 114.1 0.0 2.0 2 0 0 2 2 2 1 Nicastrin small lobe Nicastrin PF05450.15 KXS10704.1 - 1e-24 87.3 0.0 2.3e-24 86.2 0.0 1.5 1 1 0 1 1 1 1 Nicastrin EF-hand_1 PF00036.32 KXS10705.1 - 7.8e-29 97.0 13.8 1.1e-09 37.2 0.2 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KXS10705.1 - 2.4e-28 98.4 11.7 5.9e-15 55.5 2.4 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KXS10705.1 - 3.6e-22 76.3 10.6 1.7e-08 33.8 0.2 4.6 3 1 1 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 KXS10705.1 - 3.3e-20 71.7 13.9 7.9e-10 38.4 0.7 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 KXS10705.1 - 3.3e-12 45.3 10.6 1.2e-05 24.5 0.1 3.9 4 1 0 4 4 4 3 EF hand EF-hand_9 PF14658.6 KXS10705.1 - 1.5e-10 41.3 1.1 0.00021 21.5 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 KXS10705.1 - 1e-08 35.1 4.7 0.00011 22.1 0.1 2.7 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 KXS10705.1 - 0.00065 19.7 0.6 0.36 10.7 0.0 3.4 1 1 3 4 4 4 1 Caleosin related protein EF-hand_14 PF17959.1 KXS10705.1 - 0.0013 19.0 2.1 0.14 12.6 0.2 2.3 2 0 0 2 2 2 1 EF-hand domain Dockerin_1 PF00404.18 KXS10705.1 - 0.007 16.5 0.1 0.22 11.8 0.1 2.4 2 0 0 2 2 2 1 Dockerin type I domain SPARC_Ca_bdg PF10591.9 KXS10705.1 - 0.017 15.5 2.0 1.7 9.0 0.1 2.2 1 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DUF3164 PF11363.8 KXS10705.1 - 0.023 14.3 0.3 0.65 9.6 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3164) TerB PF05099.13 KXS10705.1 - 0.025 14.5 2.8 4.9 7.1 0.3 2.9 1 1 2 3 3 3 0 Tellurite resistance protein TerB EF-hand_11 PF08976.11 KXS10705.1 - 0.038 14.8 0.7 1.6 9.7 0.1 2.2 1 1 1 2 2 2 0 EF-hand domain SurA_N_2 PF13623.6 KXS10705.1 - 0.063 13.1 0.9 3.1 7.6 0.2 2.6 2 1 1 3 3 3 0 SurA N-terminal domain FlgD PF03963.14 KXS10705.1 - 0.066 13.5 0.0 0.56 10.6 0.0 2.1 2 0 0 2 2 2 0 Flagellar hook capping protein - N-terminal region DUF1296 PF06972.11 KXS10705.1 - 0.074 13.2 0.4 2.7 8.2 0.2 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1296) MgtE_N PF03448.17 KXS10705.1 - 0.18 12.5 3.9 0.17 12.5 0.7 2.4 1 1 0 2 2 2 0 MgtE intracellular N domain OTU PF02338.19 KXS10706.1 - 1.1e-25 90.6 0.1 2.1e-25 89.7 0.0 1.5 2 0 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 KXS10706.1 - 1.6e-06 27.8 0.0 0.0003 20.3 0.0 2.2 2 0 0 2 2 2 2 Peptidase C65 Otubain Zn_clus PF00172.18 KXS10707.1 - 9e-09 35.3 12.7 1.4e-08 34.7 12.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain P68HR PF08061.11 KXS10707.1 - 0.091 12.9 1.6 0.2 11.9 1.6 1.6 1 0 0 1 1 1 0 P68HR (NUC004) repeat Homeodomain PF00046.29 KXS10708.1 - 9.6e-13 47.8 0.7 2.1e-12 46.7 0.7 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KXS10708.1 - 0.022 14.7 0.1 0.058 13.3 0.1 1.7 1 0 0 1 1 1 0 Homeobox KN domain YdaS_antitoxin PF15943.5 KXS10708.1 - 0.19 11.6 0.0 0.34 10.8 0.0 1.3 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT zf-C2H2 PF00096.26 KXS10711.1 - 1.3e-06 28.5 6.6 0.0047 17.3 1.5 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KXS10711.1 - 9.8e-06 25.8 6.9 0.00059 20.2 0.4 3.9 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KXS10711.1 - 3.8e-05 24.1 10.7 0.018 15.8 1.8 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KXS10711.1 - 0.00034 20.9 0.3 0.18 12.2 0.1 2.5 1 1 1 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 KXS10711.1 - 0.025 14.9 0.3 0.088 13.1 0.1 2.0 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf_C2H2_ZHX PF18387.1 KXS10711.1 - 0.096 12.3 1.1 0.24 11.1 0.7 1.9 1 1 0 1 1 1 0 Zinc-fingers and homeoboxes C2H2 finger domain CpXC PF14353.6 KXS10711.1 - 0.13 12.3 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 CpXC protein zf-C2H2_3rep PF18868.1 KXS10711.1 - 0.14 12.9 1.7 0.44 11.2 0.3 2.2 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-met PF12874.7 KXS10711.1 - 0.26 11.7 0.1 0.26 11.7 0.1 2.9 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-BED PF02892.15 KXS10711.1 - 0.89 9.6 5.9 0.19 11.8 2.1 1.9 2 0 0 2 2 2 0 BED zinc finger zf-C2H2_6 PF13912.6 KXS10711.1 - 1.3 9.1 5.0 9.8 6.3 1.0 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KXS10711.1 - 6.6 6.6 12.7 2.3 8.0 0.0 3.3 4 0 0 4 4 4 0 C2H2-type zinc-finger domain DUF1168 PF06658.12 KXS10712.1 - 9.6e-38 129.1 2.5 9.6e-38 129.1 2.5 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1168) Nop14 PF04147.12 KXS10712.1 - 0.46 8.6 10.4 0.71 8.0 10.4 1.2 1 0 0 1 1 1 0 Nop14-like family Fungal_trans PF04082.18 KXS10716.1 - 2.7e-13 49.5 0.0 3.9e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain ATE_C PF04377.15 KXS10717.1 - 3.5e-49 166.9 0.7 6.9e-49 165.9 0.7 1.5 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 KXS10717.1 - 2.2e-31 108.1 4.4 4.6e-31 107.0 4.4 1.6 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus Acetyltransf_6 PF13480.7 KXS10717.1 - 0.062 13.4 0.1 0.14 12.3 0.1 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain adh_short PF00106.25 KXS10718.1 - 2.5e-36 125.0 0.0 3.2e-36 124.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXS10718.1 - 4.2e-23 82.1 0.0 5.8e-23 81.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXS10718.1 - 2.1e-10 40.8 0.1 3.4e-10 40.1 0.1 1.2 1 0 0 1 1 1 1 KR domain Pyr_redox PF00070.27 KXS10718.1 - 0.0002 21.8 0.1 0.00076 20.0 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 KXS10718.1 - 0.004 17.6 0.2 0.0079 16.6 0.2 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding THF_DHG_CYH_C PF02882.19 KXS10718.1 - 0.0049 16.2 0.0 0.0087 15.4 0.0 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ADH_zinc_N PF00107.26 KXS10718.1 - 0.0059 16.6 0.3 0.015 15.3 0.3 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Polysacc_synt_2 PF02719.15 KXS10718.1 - 0.0083 15.3 0.1 0.011 14.9 0.1 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3HCDH_N PF02737.18 KXS10718.1 - 0.012 15.5 0.5 0.02 14.8 0.5 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 KXS10718.1 - 0.013 15.4 1.2 0.053 13.4 1.2 1.9 1 1 0 1 1 1 0 NAD(P)H-binding DFP PF04127.15 KXS10718.1 - 0.089 12.6 0.3 0.15 11.9 0.3 1.3 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Pyr_redox_2 PF07992.14 KXS10718.1 - 0.13 11.5 0.2 0.19 10.9 0.2 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase zf-C3HC4_2 PF13923.6 KXS10719.1 - 3.1e-08 33.3 13.7 5e-08 32.7 13.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXS10719.1 - 3.4e-08 33.2 13.4 5.5e-08 32.5 13.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXS10719.1 - 5.5e-07 29.8 12.6 8.4e-07 29.2 12.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KXS10719.1 - 2.3e-06 27.5 14.1 8.9e-06 25.6 14.5 1.8 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KXS10719.1 - 1e-05 25.5 9.6 2.5e-05 24.2 9.6 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KXS10719.1 - 3e-05 23.8 15.2 4e-05 23.4 15.2 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 KXS10719.1 - 6.5e-05 22.7 7.2 0.00011 22.0 7.2 1.3 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-Nse PF11789.8 KXS10719.1 - 0.006 16.4 8.2 0.01 15.6 8.2 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.6 KXS10719.1 - 0.021 15.0 11.4 0.038 14.2 11.4 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 KXS10719.1 - 0.037 13.8 12.2 0.13 12.1 12.4 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 KXS10719.1 - 0.059 13.7 12.5 0.27 11.6 12.5 2.0 1 1 1 2 2 2 0 RING-H2 zinc finger domain DUF4689 PF15755.5 KXS10719.1 - 0.16 11.6 0.8 0.19 11.3 0.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4689) zf-RING_11 PF17123.5 KXS10719.1 - 0.44 10.3 7.3 1.2 9.0 7.3 1.8 1 0 0 1 1 1 0 RING-like zinc finger zf-Di19 PF05605.12 KXS10719.1 - 1.2 9.5 13.8 15 6.0 13.8 2.3 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding WD40 PF00400.32 KXS10720.1 - 1.8e-28 98.2 4.5 2.1e-08 34.7 0.4 4.8 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXS10720.1 - 8.9e-16 58.0 0.0 0.0001 22.6 0.0 4.4 1 1 3 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain LisH_TPL PF17814.1 KXS10720.1 - 2.6e-13 49.4 0.8 5.3e-13 48.4 0.8 1.6 1 0 0 1 1 1 1 LisH-like dimerisation domain Ge1_WD40 PF16529.5 KXS10720.1 - 2.7e-07 29.9 0.6 0.11 11.5 0.1 3.8 2 1 3 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KXS10720.1 - 0.13 12.2 0.1 1 9.3 0.0 2.5 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat F-box PF00646.33 KXS10722.1 - 0.0047 16.8 0.4 0.012 15.5 0.4 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KXS10722.1 - 0.019 14.8 0.8 0.04 13.8 0.8 1.5 1 0 0 1 1 1 0 F-box-like Peptidase_M3 PF01432.20 KXS10723.1 - 3.1e-43 148.7 0.0 6.3e-37 127.9 0.0 3.2 1 1 1 2 2 2 2 Peptidase family M3 Dickkopf_N PF04706.12 KXS10724.1 - 0.61 10.6 5.9 0.45 11.0 3.8 1.9 2 0 0 2 2 2 0 Dickkopf N-terminal cysteine-rich region EB PF01683.18 KXS10724.1 - 0.93 9.8 6.1 2.6 8.4 5.0 2.0 2 0 0 2 2 2 0 EB module Sec23_trunk PF04811.15 KXS10725.1 - 2.3e-71 240.2 0.0 3.5e-71 239.6 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 KXS10725.1 - 2e-24 85.4 0.1 5.1e-24 84.1 0.0 1.8 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 KXS10725.1 - 2.1e-19 70.1 0.0 4.1e-19 69.1 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 KXS10725.1 - 1.4e-15 57.0 5.4 2.6e-15 56.2 5.4 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 KXS10725.1 - 6e-05 22.9 0.0 0.00017 21.4 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 KXS10725.1 - 0.012 15.0 0.1 0.027 13.9 0.1 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Cys_Met_Meta_PP PF01053.20 KXS10727.1 - 1.4e-136 455.0 0.0 1.7e-136 454.8 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme CoA_binding_2 PF13380.6 KXS10727.1 - 4.1e-34 117.5 0.1 5.6e-33 113.9 0.1 2.4 2 0 0 2 2 2 1 CoA binding domain Aminotran_1_2 PF00155.21 KXS10727.1 - 3.8e-08 32.9 0.0 6.5e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 KXS10727.1 - 1.5e-07 31.1 0.0 2.6e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 KXS10727.1 - 3e-06 26.5 0.0 5.2e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KXS10727.1 - 4.3e-05 22.9 0.0 0.00011 21.6 0.0 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase CoA_binding PF02629.19 KXS10727.1 - 0.00097 19.8 0.2 0.0061 17.2 0.0 2.2 2 0 0 2 2 2 1 CoA binding domain GDC-P PF02347.16 KXS10727.1 - 0.024 13.5 0.0 0.035 12.9 0.0 1.1 1 0 0 1 1 1 0 Glycine cleavage system P-protein BTRD1 PF17660.1 KXS10727.1 - 0.062 13.1 0.1 0.53 10.1 0.0 2.3 2 0 0 2 2 2 0 Bacterial tandem repeat domain 1 Cys_Met_Meta_PP PF01053.20 KXS10730.1 - 4.3e-134 446.8 0.0 5.2e-134 446.6 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme CoA_binding_2 PF13380.6 KXS10730.1 - 1.7e-37 128.4 0.1 5.4e-37 126.8 0.1 1.9 1 0 0 1 1 1 1 CoA binding domain Aminotran_1_2 PF00155.21 KXS10730.1 - 2.1e-09 37.0 0.0 3.5e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 KXS10730.1 - 1.9e-06 27.5 0.0 4.8e-06 26.1 0.0 1.6 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 KXS10730.1 - 2.8e-06 26.5 0.0 6.8e-06 25.3 0.0 1.6 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KXS10730.1 - 0.0012 18.2 0.0 0.0037 16.6 0.0 1.7 1 1 0 1 1 1 1 Beta-eliminating lyase CoA_binding PF02629.19 KXS10730.1 - 0.008 16.8 0.0 0.036 14.7 0.0 2.1 3 0 0 3 3 3 1 CoA binding domain DUF4604 PF15377.6 KXS10731.1 - 6.3e-10 39.8 8.1 9.3e-10 39.2 8.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) BING4CT PF08149.11 KXS10732.1 - 4.8e-42 141.6 0.0 7e-39 131.5 0.0 3.4 3 0 0 3 3 3 2 BING4CT (NUC141) domain ANAPC4_WD40 PF12894.7 KXS10732.1 - 6.2e-05 23.2 0.0 1.2 9.5 0.0 3.9 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 KXS10732.1 - 9.2e-05 21.7 0.0 0.00014 21.1 0.0 1.2 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.32 KXS10732.1 - 9.8e-05 23.1 0.0 0.089 13.7 0.0 4.7 5 0 0 5 5 5 1 WD domain, G-beta repeat PQQ_2 PF13360.6 KXS10732.1 - 0.0022 17.6 0.0 0.005 16.5 0.0 1.6 1 1 0 1 1 1 1 PQQ-like domain zf-CCCH_4 PF18044.1 KXS10733.1 - 3.6e-18 64.9 30.1 6.4e-07 29.0 0.6 4.7 4 0 0 4 4 4 4 CCCH-type zinc finger Torus PF16131.5 KXS10733.1 - 7.7e-13 49.1 18.8 1.7e-05 25.4 0.1 4.4 3 1 1 4 4 4 4 Torus domain zf-CCCH PF00642.24 KXS10733.1 - 4.5e-10 39.2 30.8 0.0014 18.5 0.2 4.6 4 0 0 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KXS10733.1 - 2.9e-09 36.7 41.1 0.0002 21.3 5.5 5.2 4 1 0 4 4 4 3 Zinc finger domain zf-C3HC4 PF00097.25 KXS10733.1 - 6.2e-07 29.2 4.7 6.2e-07 29.2 4.7 2.5 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXS10733.1 - 6.6e-07 29.6 6.2 6.6e-07 29.6 6.2 3.7 4 0 0 4 4 4 1 Ring finger domain zf-RING_5 PF14634.6 KXS10733.1 - 8.6e-07 28.8 5.3 8.6e-07 28.8 5.3 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KXS10733.1 - 4.4e-05 23.3 4.2 4.4e-05 23.3 4.2 3.0 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXS10733.1 - 0.00039 20.4 3.1 0.001 19.0 3.1 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-CCCH_3 PF15663.5 KXS10733.1 - 0.00062 20.0 1.4 0.00062 20.0 1.4 2.8 3 0 0 3 3 3 1 Zinc-finger containing family zf-C3HC4_4 PF15227.6 KXS10733.1 - 0.0015 18.6 4.0 0.0015 18.6 4.0 2.8 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 KXS10733.1 - 0.0034 17.6 6.6 0.0034 17.6 6.6 2.2 2 1 0 2 2 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KXS10733.1 - 0.0041 16.9 5.7 0.0041 16.9 5.7 3.0 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KXS10733.1 - 0.029 14.4 0.8 0.029 14.4 0.8 2.2 2 0 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger RNF220 PF15926.5 KXS10733.1 - 0.14 11.7 4.4 0.053 13.1 1.6 1.6 2 0 0 2 2 2 0 E3 ubiquitin-protein ligase RNF220 zf-CCHH PF10283.9 KXS10733.1 - 1.3 9.0 6.8 16 5.6 2.3 3.3 2 0 0 2 2 2 0 PBZ domain zf-RING_10 PF16685.5 KXS10733.1 - 1.7 8.8 7.0 2.5 8.3 1.8 2.6 2 0 0 2 2 2 0 zinc RING finger of MSL2 Prok-RING_4 PF14447.6 KXS10733.1 - 2.1 8.3 12.8 0.091 12.6 5.7 2.6 2 1 1 3 3 2 0 Prokaryotic RING finger family 4 zinc_ribbon_9 PF14369.6 KXS10733.1 - 5.3 7.4 7.3 1.9 8.8 2.0 2.6 2 0 0 2 2 2 0 zinc-ribbon Amidohydro_1 PF01979.20 KXS10734.1 - 1.3e-11 44.4 0.1 2.3e-11 43.6 0.1 1.4 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_2 PF04909.14 KXS10734.1 - 7.1e-08 32.6 0.6 1.8e-07 31.2 0.0 1.9 3 0 0 3 3 3 1 Amidohydrolase Pkinase PF00069.25 KXS10735.1 - 3.2e-17 62.8 0.0 3.3e-17 62.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS10735.1 - 5.7e-10 38.9 0.0 6.6e-10 38.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase RabGAP-TBC PF00566.18 KXS10736.1 - 2.3e-16 60.1 0.3 1.2e-15 57.8 0.3 1.9 1 1 0 1 1 1 1 Rab-GTPase-TBC domain DUF2397 PF09660.10 KXS10736.1 - 0.22 10.4 0.0 0.33 9.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2397) SMK-1 PF04802.15 KXS10737.1 - 1.9e-40 138.8 0.0 3.6e-40 137.8 0.0 1.5 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 Aldo_ket_red PF00248.21 KXS10739.1 - 3.1e-42 144.8 0.0 1e-31 110.3 0.0 2.0 2 0 0 2 2 2 2 Aldo/keto reductase family DUF4490 PF14892.6 KXS10740.1 - 5.1e-15 55.4 0.2 5.7e-15 55.2 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4490) HSF_DNA-bind PF00447.17 KXS10742.1 - 1.1e-26 93.3 0.0 1.2e-26 93.2 0.0 1.0 1 0 0 1 1 1 1 HSF-type DNA-binding DUF3558 PF12079.8 KXS10743.1 - 2.2 8.3 5.5 2.7 8.0 5.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3558) Pkinase PF00069.25 KXS10744.1 - 5.5e-16 58.7 0.1 3.6e-14 52.8 0.1 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS10744.1 - 0.00022 20.6 0.0 0.013 14.8 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 KXS10744.1 - 0.0075 15.9 0.0 0.64 9.6 0.0 2.2 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KXS10744.1 - 0.015 15.2 0.0 0.029 14.3 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 KXS10744.1 - 0.019 14.3 0.0 0.034 13.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Fructosamin_kin PF03881.14 KXS10744.1 - 0.026 13.8 0.1 0.59 9.3 0.0 2.1 1 1 1 2 2 2 0 Fructosamine kinase Integrase_H2C2 PF17921.1 KXS10745.1 - 1.1e-09 38.3 0.0 2.1e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain SMP_2 PF10144.9 KXS10748.1 - 0.036 13.7 0.9 0.036 13.7 0.9 1.7 2 0 0 2 2 2 0 Bacterial virulence factor haemolysin Ldt_C PF17969.1 KXS10748.1 - 0.08 13.7 2.1 6.1 7.7 0.8 2.7 1 1 1 2 2 2 0 L,D-transpeptidase C-terminal domain Glyco_tranf_2_3 PF13641.6 KXS10749.1 - 0.0013 18.6 0.0 0.0017 18.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Abhydrolase_1 PF00561.20 KXS10751.1 - 2.9e-14 53.3 0.1 8.8e-14 51.8 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold FSH1 PF03959.13 KXS10751.1 - 0.0052 16.5 0.0 0.36 10.5 0.0 2.2 1 1 1 2 2 2 2 Serine hydrolase (FSH1) Hydrolase_4 PF12146.8 KXS10751.1 - 0.015 14.6 0.0 0.28 10.4 0.0 2.2 1 1 0 1 1 1 0 Serine aminopeptidase, S33 PRIMA1 PF16101.5 KXS10752.1 - 1.5 8.9 9.7 0.97 9.5 2.7 2.4 3 0 0 3 3 3 0 Proline-rich membrane anchor 1 Ank_2 PF12796.7 KXS10753.1 - 5.8e-15 55.7 0.0 2e-11 44.3 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXS10753.1 - 3.3e-10 40.3 0.0 0.00011 22.6 0.0 3.8 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXS10753.1 - 1.2e-09 37.6 0.0 0.26 12.0 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 KXS10753.1 - 1e-05 25.7 0.2 1.8 9.1 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 KXS10753.1 - 0.00029 21.1 0.1 0.74 10.2 0.0 3.7 1 1 3 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXS10754.1 - 2e-22 79.3 0.3 2.8e-05 24.6 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXS10754.1 - 3e-19 69.4 0.8 1.2e-07 32.2 0.1 4.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXS10754.1 - 1.9e-18 64.6 2.8 0.0005 20.3 0.0 6.1 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 KXS10754.1 - 2.4e-16 59.6 2.0 0.00022 21.4 0.0 4.9 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 KXS10754.1 - 4.4e-11 42.7 1.8 0.29 11.6 0.2 5.7 6 0 0 6 6 6 3 Ankyrin repeat DUF3447 PF11929.8 KXS10754.1 - 0.0052 16.7 0.0 0.19 11.7 0.0 2.3 1 1 1 2 2 2 1 Domain of unknown function (DUF3447) F-box-like PF12937.7 KXS10755.1 - 5.2e-09 35.9 0.5 1.2e-08 34.7 0.5 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXS10755.1 - 8.1e-06 25.6 0.1 1.8e-05 24.5 0.1 1.5 1 0 0 1 1 1 1 F-box domain FH2 PF02181.23 KXS10756.1 - 4e-58 197.3 13.7 8.8e-30 104.1 1.5 4.3 4 0 0 4 4 4 3 Formin Homology 2 Domain Drf_FH3 PF06367.16 KXS10756.1 - 0.0036 17.0 1.9 0.015 15.0 0.0 2.5 2 1 0 2 2 2 1 Diaphanous FH3 Domain MWFE PF15879.5 KXS10756.1 - 0.11 12.7 1.3 0.28 11.4 0.0 2.4 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase MWFE subunit DUF4355 PF14265.6 KXS10756.1 - 4.4 7.6 9.2 3.1 8.0 4.7 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) DSPn PF14671.6 KXS10757.1 - 1.4e-43 148.7 0.0 3.6e-43 147.4 0.0 1.7 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 KXS10757.1 - 2.7e-13 49.9 0.0 1.1e-12 47.9 0.0 2.0 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KXS10757.1 - 5.3e-05 22.9 0.0 8.3e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 KXS10757.1 - 0.00024 21.3 0.0 0.00037 20.6 0.0 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 KXS10757.1 - 0.071 13.1 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family CPSase_L_D2 PF02786.17 KXS10758.1 - 1.3e-101 338.5 0.1 7.4e-85 283.7 0.0 3.1 2 1 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 KXS10758.1 - 6.5e-39 133.1 0.1 2.7e-38 131.0 0.1 2.1 1 1 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp PF02222.22 KXS10758.1 - 2.7e-15 56.4 0.1 3.5e-08 33.2 0.0 2.7 2 1 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.13 KXS10758.1 - 2.8e-15 56.4 0.9 7.8e-09 35.4 0.1 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 KXS10758.1 - 4.8e-06 26.3 0.0 0.047 13.4 0.0 3.4 3 1 0 3 3 3 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.14 KXS10758.1 - 1.1e-05 25.6 0.2 0.012 15.7 0.1 2.4 2 0 0 2 2 2 2 ATP-grasp domain GARS_A PF01071.19 KXS10758.1 - 5.7e-05 23.0 0.2 0.29 10.9 0.0 2.4 2 0 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RimK PF08443.11 KXS10758.1 - 0.00012 21.7 0.0 0.64 9.6 0.0 2.7 2 1 0 2 2 2 2 RimK-like ATP-grasp domain ATP-grasp_5 PF13549.6 KXS10758.1 - 0.00041 19.9 0.1 0.079 12.4 0.0 2.5 2 0 0 2 2 2 1 ATP-grasp domain DUF3215 PF11503.8 KXS10758.1 - 0.00096 19.0 0.1 0.003 17.4 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3215) TrkA_N PF02254.18 KXS10758.1 - 0.013 15.7 0.1 2.3 8.5 0.0 3.1 3 0 0 3 3 3 0 TrkA-N domain Phage_TAC_2 PF06894.11 KXS10760.1 - 0.16 11.8 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage lambda tail assembly chaperone, TAC, protein G Myb_DNA-bind_3 PF12776.7 KXS10761.1 - 1.6e-15 57.9 0.9 3.5e-15 56.8 0.9 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Ank_3 PF13606.6 KXS10761.1 - 9.3e-05 22.6 0.1 1.8 9.4 0.0 3.9 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 KXS10761.1 - 0.00045 20.7 0.2 1.7 9.3 0.0 3.9 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXS10761.1 - 0.00048 20.7 0.0 3.5 8.3 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Rootletin PF15035.6 KXS10761.1 - 0.009 16.1 0.0 0.017 15.2 0.0 1.3 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion YabA PF06156.13 KXS10761.1 - 0.0093 16.6 0.1 0.02 15.5 0.1 1.5 1 0 0 1 1 1 1 Initiation control protein YabA DUF573 PF04504.14 KXS10761.1 - 0.016 15.9 0.5 0.044 14.4 0.5 1.8 1 0 0 1 1 1 0 Protein of unknown function, DUF573 KASH_CCD PF14662.6 KXS10761.1 - 0.019 14.8 0.2 0.033 14.0 0.2 1.3 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH TSC22 PF01166.18 KXS10761.1 - 0.035 14.4 0.9 0.39 11.1 0.4 2.3 1 1 1 2 2 2 0 TSC-22/dip/bun family K-box PF01486.17 KXS10761.1 - 0.043 14.0 3.6 15 5.9 2.8 3.2 2 1 0 2 2 2 0 K-box region DivIC PF04977.15 KXS10761.1 - 0.068 13.0 2.4 0.54 10.1 0.7 2.4 1 1 1 2 2 2 0 Septum formation initiator rhaM PF05336.13 KXS10761.1 - 0.16 12.0 0.6 8.6 6.5 0.1 2.4 2 0 0 2 2 2 0 L-rhamnose mutarotase ADIP PF11559.8 KXS10761.1 - 0.39 10.8 4.8 0.64 10.1 4.1 1.6 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding ZapB PF06005.12 KXS10761.1 - 0.69 10.4 4.7 1.2 9.6 2.4 2.5 2 1 0 2 2 2 0 Cell division protein ZapB DDE_Tnp_IS66 PF03050.14 KXS10762.1 - 0.12 11.8 0.1 0.16 11.4 0.1 1.1 1 0 0 1 1 1 0 Transposase IS66 family Lipase_3 PF01764.25 KXS10764.1 - 3.2e-14 53.0 0.0 5.3e-14 52.3 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Mpv17_PMP22 PF04117.12 KXS10765.1 - 5.9e-23 80.9 2.7 9.8e-23 80.2 2.7 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family DUF2530 PF10745.9 KXS10765.1 - 0.044 14.0 0.8 0.11 12.8 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2530) NmrA PF05368.13 KXS10766.1 - 1e-15 57.9 0.0 1.4e-15 57.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXS10766.1 - 3.4e-13 49.9 0.0 6.3e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Mpv17_PMP22 PF04117.12 KXS10767.1 - 5.1e-23 81.1 3.6 5.1e-23 81.1 3.6 1.8 2 0 0 2 2 2 1 Mpv17 / PMP22 family Pkinase PF00069.25 KXS10769.1 - 6.3e-69 232.3 0.0 7.2e-69 232.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS10769.1 - 2.4e-36 125.4 0.0 3.2e-36 124.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXS10769.1 - 0.012 14.9 0.0 0.017 14.4 0.0 1.4 1 1 0 1 1 1 0 Kinase-like YrbL-PhoP_reg PF10707.9 KXS10769.1 - 0.085 12.4 0.0 0.16 11.5 0.0 1.4 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL zf-C5HC2 PF02928.16 KXS10770.1 - 0.058 13.8 0.1 0.099 13.0 0.1 1.5 1 0 0 1 1 1 0 C5HC2 zinc finger AIG2_2 PF13772.6 KXS10771.1 - 0.026 14.9 0.0 0.054 13.9 0.0 1.5 1 0 0 1 1 1 0 AIG2-like family cobW PF02492.19 KXS10772.1 - 4.7e-35 120.8 0.0 6.4e-35 120.3 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 KXS10772.1 - 0.00013 21.9 0.0 0.00022 21.1 0.0 1.4 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain T2SSE PF00437.20 KXS10772.1 - 0.00046 19.3 0.0 0.00075 18.6 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein MobB PF03205.14 KXS10772.1 - 0.0011 18.8 0.0 0.0049 16.8 0.0 2.0 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B TsaE PF02367.17 KXS10772.1 - 0.002 18.1 0.0 0.025 14.6 0.0 2.2 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE KTI12 PF08433.10 KXS10772.1 - 0.014 14.9 0.0 0.027 13.9 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_16 PF13191.6 KXS10772.1 - 0.014 15.8 0.0 0.025 14.9 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 KXS10772.1 - 0.019 15.2 0.0 0.036 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KXS10772.1 - 0.024 14.5 0.0 1.4 8.8 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase AAA_14 PF13173.6 KXS10772.1 - 0.032 14.3 0.0 0.074 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KXS10772.1 - 0.033 13.5 0.0 0.065 12.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_33 PF13671.6 KXS10772.1 - 0.036 14.2 0.0 0.1 12.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KXS10772.1 - 0.039 13.9 0.0 0.099 12.5 0.0 1.7 1 0 0 1 1 1 0 NTPase AAA_18 PF13238.6 KXS10772.1 - 0.072 13.6 0.0 0.18 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 KXS10772.1 - 0.16 12.0 0.1 1.7 8.8 0.0 2.2 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_7 PF12775.7 KXS10772.1 - 0.24 10.9 0.0 0.37 10.3 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region Acyl-CoA_dh_1 PF00441.24 KXS10773.1 - 4.2e-28 98.4 2.4 6.5e-28 97.8 2.4 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KXS10773.1 - 2.1e-16 60.6 0.0 5.5e-16 59.2 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KXS10773.1 - 7.4e-15 54.9 0.0 1.4e-14 54.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KXS10773.1 - 8.8e-05 22.8 0.1 8.8e-05 22.8 0.1 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Toprim_2 PF13155.6 KXS10773.1 - 0.13 12.7 0.1 1.8 9.1 0.0 2.3 2 0 0 2 2 2 0 Toprim-like adh_short_C2 PF13561.6 KXS10774.1 - 6.8e-30 104.4 2.0 1.7e-29 103.1 2.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXS10774.1 - 1.2e-28 100.0 0.7 1.8e-28 99.3 0.7 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXS10774.1 - 1.4e-06 28.4 0.3 1.8e-06 28.0 0.3 1.3 1 0 0 1 1 1 1 KR domain AdoHcyase_NAD PF00670.21 KXS10774.1 - 0.021 14.9 0.1 0.039 14.0 0.1 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain SH3_9 PF14604.6 KXS10776.1 - 3.2e-06 26.9 0.0 7.8e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXS10776.1 - 0.0024 17.4 0.0 0.0067 16.0 0.0 1.8 2 0 0 2 2 2 1 SH3 domain Gelsolin PF00626.22 KXS10777.1 - 2.2e-17 62.7 0.0 0.0053 16.6 0.0 5.8 5 0 0 5 5 5 5 Gelsolin repeat VHP PF02209.19 KXS10777.1 - 1.2e-11 44.5 4.8 2.6e-11 43.4 4.8 1.6 1 0 0 1 1 1 1 Villin headpiece domain Fungal_trans PF04082.18 KXS10778.1 - 8.5e-16 57.8 0.1 9.3e-16 57.6 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain RGS PF00615.19 KXS10779.1 - 3.3e-10 40.2 0.4 1.7e-05 25.1 0.0 3.1 2 1 1 3 3 3 3 Regulator of G protein signaling domain DUF21 PF01595.20 KXS10780.1 - 1.5e-30 106.2 0.1 3.3e-27 95.3 0.0 2.3 2 0 0 2 2 2 2 Cyclin M transmembrane N-terminal domain CBS PF00571.28 KXS10780.1 - 6.6e-06 26.5 3.6 0.00051 20.4 0.3 3.1 2 1 0 2 2 2 2 CBS domain B_lectin PF01453.24 KXS10781.1 - 5.9e-09 36.4 0.0 0.0051 17.3 0.0 2.4 3 0 0 3 3 3 2 D-mannose binding lectin PQQ_3 PF13570.6 KXS10781.1 - 0.01 16.3 0.2 12 6.5 0.0 3.3 1 1 1 2 2 2 0 PQQ-like domain PQQ_2 PF13360.6 KXS10781.1 - 0.012 15.2 0.1 0.058 13.0 0.1 2.0 1 1 1 2 2 2 0 PQQ-like domain PQQ PF01011.21 KXS10781.1 - 0.029 14.3 0.1 0.25 11.4 0.0 2.5 3 0 0 3 3 3 0 PQQ enzyme repeat RHS PF03527.14 KXS10781.1 - 0.14 11.9 5.5 6.7 6.6 0.1 3.2 3 0 0 3 3 3 0 RHS protein ParA PF10609.9 KXS10781.1 - 0.2 11.1 0.0 0.27 10.7 0.0 1.2 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase Reeler PF02014.16 KXS10782.1 - 6.2e-08 33.5 0.0 9.2e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Reeler domain Rib_recp_KP_reg PF05104.12 KXS10782.1 - 0.36 11.8 27.4 0.52 11.3 27.4 1.2 1 0 0 1 1 1 0 Ribosome receptor lysine/proline rich region Phi_1 PF04674.12 KXS10783.1 - 2e-05 24.1 1.0 0.049 12.9 0.1 2.2 2 0 0 2 2 2 2 Phosphate-induced protein 1 conserved region LRR_8 PF13855.6 KXS10783.1 - 0.0022 17.7 4.5 0.022 14.5 4.0 2.5 1 1 2 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 KXS10783.1 - 0.085 13.3 10.0 0.41 11.1 0.4 3.9 2 1 1 4 4 4 0 Leucine Rich repeats (2 copies) Phi_1 PF04674.12 KXS10784.1 - 3.5e-07 29.8 0.0 4.9e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Phosphate-induced protein 1 conserved region EF-hand_4 PF12763.7 KXS10785.1 - 0.0021 18.0 0.0 1.9 8.5 0.0 2.3 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand Nucleo_P87 PF07267.11 KXS10785.1 - 1.8 7.3 7.9 2.4 6.9 7.9 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 TFIIA PF03153.13 KXS10785.1 - 3.5 7.5 22.7 4.3 7.2 22.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RhoGEF PF00621.20 KXS10786.1 - 8.2e-46 156.5 2.2 1.1e-45 156.1 2.2 1.2 1 0 0 1 1 1 1 RhoGEF domain PH_13 PF16652.5 KXS10786.1 - 4.1e-15 55.9 0.1 2.4e-14 53.4 0.0 2.1 1 1 1 2 2 2 1 Pleckstrin homology domain PUA_2 PF14306.6 KXS10786.1 - 9e-05 22.2 0.1 0.00017 21.3 0.1 1.4 1 0 0 1 1 1 1 PUA-like domain PH_5 PF15405.6 KXS10786.1 - 0.00032 20.8 0.0 0.0011 19.0 0.0 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain PH_16 PF17838.1 KXS10786.1 - 0.034 14.0 0.0 0.11 12.3 0.0 1.9 1 0 0 1 1 1 0 PH domain C2 PF00168.30 KXS10787.1 - 7.2e-07 29.5 0.0 8.4e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 C2 domain Mito_carr PF00153.27 KXS10788.1 - 8.7e-61 201.9 2.2 1.5e-21 76.1 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein F-box-like PF12937.7 KXS10791.1 - 6.4e-07 29.2 0.9 1.7e-06 27.8 0.9 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXS10791.1 - 3.9e-06 26.6 2.3 3.9e-06 26.6 2.3 2.1 2 0 0 2 2 2 1 F-box domain DUF742 PF05331.11 KXS10791.1 - 0.0043 16.9 0.4 0.025 14.4 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF742) COesterase PF00135.28 KXS10792.1 - 1.8e-93 314.2 0.0 2.3e-93 313.8 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXS10792.1 - 3.2e-11 43.5 3.1 5.1e-07 29.8 0.0 2.8 3 0 0 3 3 3 2 alpha/beta hydrolase fold Chitin_bind_1 PF00187.19 KXS10792.1 - 5.4e-08 33.2 18.2 5.4e-08 33.2 18.2 2.2 2 0 0 2 2 2 1 Chitin recognition protein Peptidase_S9 PF00326.21 KXS10792.1 - 0.0082 15.6 0.1 0.015 14.8 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family CCDC53 PF10152.9 KXS10793.1 - 0.015 15.8 0.4 0.015 15.8 0.4 4.3 4 2 0 4 4 4 0 Subunit CCDC53 of WASH complex CENP-Q PF13094.6 KXS10793.1 - 0.015 15.5 2.4 0.015 15.5 2.4 2.1 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF4200 PF13863.6 KXS10793.1 - 0.028 14.8 0.9 0.05 14.0 0.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Laminin_II PF06009.12 KXS10793.1 - 0.097 12.7 0.7 0.18 11.8 0.7 1.3 1 0 0 1 1 1 0 Laminin Domain II Nucleo_P87 PF07267.11 KXS10793.1 - 0.68 8.7 7.2 0.023 13.6 0.6 1.8 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 E1-N PF14463.6 KXS10795.1 - 0.36 10.6 3.9 0.19 11.5 1.4 1.7 2 0 0 2 2 2 0 E1 N-terminal domain LigB PF02900.18 KXS10799.1 - 1.6e-07 30.7 0.0 2e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase DHC_N1 PF08385.12 KXS10801.1 - 2.7e-169 564.4 0.2 2.7e-169 564.4 0.2 3.4 4 0 0 4 4 3 1 Dynein heavy chain, N-terminal region 1 MT PF12777.7 KXS10801.1 - 2.3e-161 536.6 16.4 4.1e-161 535.7 16.4 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_6 PF12774.7 KXS10801.1 - 3.1e-156 519.4 0.1 1.1e-153 511.0 0.0 2.9 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 KXS10801.1 - 7.5e-126 420.4 9.2 7.5e-126 420.4 9.2 4.3 5 1 0 5 5 4 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 KXS10801.1 - 8.1e-103 343.3 0.0 1.3e-101 339.4 0.0 2.8 3 0 0 3 3 3 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 KXS10801.1 - 1.5e-94 316.7 1.3 3.2e-94 315.6 0.2 2.2 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 KXS10801.1 - 8.7e-84 280.0 0.2 4.5e-83 277.7 0.0 2.4 2 0 0 2 2 2 1 ATP-binding dynein motor region AAA_7 PF12775.7 KXS10801.1 - 1.2e-74 249.7 0.1 2.4e-69 232.5 0.0 3.7 3 0 0 3 3 3 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 KXS10801.1 - 1.3e-53 181.2 0.4 1.5e-50 171.3 0.0 2.8 2 0 0 2 2 2 2 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 KXS10801.1 - 8e-41 138.9 0.0 1.8e-38 131.3 0.0 4.0 3 0 0 3 3 3 1 Dynein heavy chain region D6 P-loop domain AAA_lid_1 PF17857.1 KXS10801.1 - 8.6e-39 131.8 0.8 8.6e-39 131.8 0.8 3.1 3 0 0 3 3 2 1 AAA+ lid domain AAA_5 PF07728.14 KXS10801.1 - 4.5e-26 91.5 0.0 1.3e-11 44.6 0.0 6.4 6 1 0 6 6 6 4 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 KXS10801.1 - 3.4e-25 88.6 0.5 1.5e-24 86.5 0.5 2.3 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_16 PF13191.6 KXS10801.1 - 5.7e-09 36.6 0.2 0.0018 18.7 0.0 5.6 5 0 0 5 5 5 2 AAA ATPase domain AAA_22 PF13401.6 KXS10801.1 - 4.5e-07 30.2 0.1 0.21 11.9 0.0 4.3 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 KXS10801.1 - 2.8e-06 27.9 0.7 0.017 15.7 0.0 4.6 4 0 0 4 4 4 1 AAA domain AAA PF00004.29 KXS10801.1 - 3.9e-06 27.3 0.9 0.52 10.7 0.0 5.1 5 0 0 5 5 4 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 KXS10801.1 - 4.4e-05 24.0 0.1 0.62 10.6 0.0 3.9 3 0 0 3 3 2 2 ABC transporter AAA_30 PF13604.6 KXS10801.1 - 0.00014 21.7 0.8 1.5 8.5 0.0 3.9 4 0 0 4 4 3 1 AAA domain AAA_19 PF13245.6 KXS10801.1 - 0.00046 20.5 0.5 4.6 7.6 0.0 4.4 3 0 0 3 3 3 0 AAA domain AAA_14 PF13173.6 KXS10801.1 - 0.00047 20.2 0.0 1.3 9.0 0.0 4.1 4 0 0 4 4 4 1 AAA domain NB-ARC PF00931.22 KXS10801.1 - 0.0007 18.8 2.2 0.56 9.3 0.0 4.3 5 0 0 5 5 4 1 NB-ARC domain TsaE PF02367.17 KXS10801.1 - 0.0026 17.7 0.6 2 8.4 0.0 3.8 3 0 0 3 3 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 KXS10801.1 - 0.0031 16.7 0.0 0.71 9.0 0.0 3.3 3 0 0 3 3 3 1 Protein of unknown function (DUF815) NACHT PF05729.12 KXS10801.1 - 0.0045 16.9 0.0 0.69 9.8 0.0 3.3 2 0 0 2 2 2 1 NACHT domain ATP-synt_ab PF00006.25 KXS10801.1 - 0.0046 16.6 0.0 0.42 10.2 0.0 2.6 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain RNA_helicase PF00910.22 KXS10801.1 - 0.0047 17.3 0.0 56 4.2 0.0 4.3 4 0 0 4 4 3 0 RNA helicase Viral_helicase1 PF01443.18 KXS10801.1 - 0.0075 16.0 0.0 1.9 8.1 0.0 3.4 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase APG6_N PF17675.1 KXS10801.1 - 0.0077 16.8 0.8 0.0077 16.8 0.8 6.1 6 1 0 6 6 2 1 Apg6 coiled-coil region AAA_29 PF13555.6 KXS10801.1 - 0.013 15.3 0.2 32 4.4 0.0 3.6 3 0 0 3 3 3 0 P-loop containing region of AAA domain Mg_chelatase PF01078.21 KXS10801.1 - 0.023 14.1 0.1 14 5.0 0.0 3.5 4 0 0 4 4 4 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 KXS10801.1 - 0.036 13.4 0.2 4.7 6.4 0.0 3.2 3 0 0 3 3 2 0 Zeta toxin Sigma54_activ_2 PF14532.6 KXS10801.1 - 0.039 14.1 0.0 22 5.2 0.0 3.6 4 0 0 4 4 2 0 Sigma-54 interaction domain PhoH PF02562.16 KXS10801.1 - 0.065 12.7 0.8 29 4.0 0.0 3.6 3 0 0 3 3 3 0 PhoH-like protein BRE1 PF08647.11 KXS10801.1 - 0.081 13.0 22.6 0.046 13.8 4.7 4.3 3 0 0 3 3 3 0 BRE1 E3 ubiquitin ligase AAA_33 PF13671.6 KXS10801.1 - 0.15 12.2 0.5 1.1e+02 3.0 0.0 3.9 4 0 0 4 4 3 0 AAA domain PduV-EutP PF10662.9 KXS10801.1 - 0.21 11.4 0.5 5.9 6.6 0.1 3.2 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Laminin_II PF06009.12 KXS10801.1 - 0.39 10.7 24.5 0.0088 16.1 1.0 6.0 5 0 0 5 5 4 0 Laminin Domain II Nup54 PF13874.6 KXS10801.1 - 4.1 7.5 8.1 2.4 8.3 0.1 3.5 3 0 0 3 3 2 0 Nucleoporin complex subunit 54 Spc7 PF08317.11 KXS10801.1 - 4.3 6.1 45.7 0.13 11.1 6.4 5.7 6 0 0 6 6 5 0 Spc7 kinetochore protein Cob_adeno_trans PF01923.18 KXS10801.1 - 4.4 7.4 5.1 83 3.3 0.1 3.8 2 0 0 2 2 2 0 Cobalamin adenosyltransferase MerR-DNA-bind PF09278.11 KXS10801.1 - 7.8 7.1 7.4 11 6.6 2.0 4.1 4 0 0 4 4 3 0 MerR, DNA binding SQS_PSY PF00494.19 KXS10802.1 - 2e-42 145.5 0.0 2.8e-42 145.0 0.0 1.2 1 0 0 1 1 1 1 Squalene/phytoene synthase AA_permease_2 PF13520.6 KXS10804.1 - 7.4e-55 186.5 47.3 8.7e-55 186.2 47.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXS10804.1 - 6.3e-18 64.6 42.2 8.7e-18 64.2 42.2 1.1 1 0 0 1 1 1 1 Amino acid permease Ribosomal_L13 PF00572.18 KXS10805.1 - 1.1e-12 48.3 0.6 1.2e-10 41.7 0.0 2.6 2 1 0 2 2 2 1 Ribosomal protein L13 Seryl_tRNA_N PF02403.22 KXS10805.1 - 0.019 15.2 1.5 0.026 14.7 1.5 1.2 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain ELFV_dehydrog PF00208.21 KXS10805.1 - 0.16 11.6 1.0 0.28 10.8 1.0 1.4 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase APS_kinase PF01583.20 KXS10806.1 - 1.6e-74 249.0 0.0 2e-74 248.8 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.6 KXS10806.1 - 6.3e-08 32.9 0.0 1.3e-07 31.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KXS10806.1 - 0.00014 22.4 0.0 0.00025 21.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 KXS10806.1 - 0.0037 16.7 0.0 0.0043 16.6 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 CPT PF07931.12 KXS10806.1 - 0.015 15.1 0.2 0.14 12.0 0.2 2.3 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Zeta_toxin PF06414.12 KXS10806.1 - 0.022 14.0 0.0 0.054 12.8 0.0 1.5 2 1 0 2 2 2 0 Zeta toxin AAA_16 PF13191.6 KXS10806.1 - 0.024 15.0 0.1 0.031 14.7 0.1 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 KXS10806.1 - 0.025 14.3 0.0 0.042 13.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 KXS10806.1 - 0.051 14.1 0.0 0.064 13.8 0.0 1.4 1 1 0 1 1 1 0 ABC transporter G-alpha PF00503.20 KXS10806.1 - 0.093 11.9 0.0 0.15 11.2 0.0 1.2 1 1 0 1 1 1 0 G-protein alpha subunit 6PF2K PF01591.18 KXS10806.1 - 0.15 11.3 0.0 0.26 10.6 0.0 1.4 2 0 0 2 2 2 0 6-phosphofructo-2-kinase Flavi_M PF01004.19 KXS10807.1 - 0.0094 15.7 3.5 0.66 9.8 0.1 3.7 1 1 3 4 4 4 2 Flavivirus envelope glycoprotein M AAA_18 PF13238.6 KXS10809.1 - 1.3e-25 90.4 0.0 2.1e-25 89.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KXS10809.1 - 9.9e-05 22.5 0.2 0.03 14.5 0.1 2.4 1 1 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KXS10809.1 - 0.00014 22.2 1.6 0.00035 20.8 0.1 2.2 1 1 0 2 2 2 1 AAA domain AAA_17 PF13207.6 KXS10809.1 - 0.00027 21.4 0.0 0.00061 20.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KXS10809.1 - 0.00052 20.4 0.1 0.00099 19.5 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain SKI PF01202.22 KXS10809.1 - 0.00088 19.4 0.0 0.0014 18.8 0.0 1.3 1 0 0 1 1 1 1 Shikimate kinase AAA_22 PF13401.6 KXS10809.1 - 0.0018 18.6 0.0 0.0042 17.4 0.0 1.6 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.18 KXS10809.1 - 0.0025 17.2 0.0 0.0053 16.1 0.0 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family T2SSE PF00437.20 KXS10809.1 - 0.0034 16.5 0.0 0.005 15.9 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA PF00004.29 KXS10809.1 - 0.0054 17.1 0.0 0.0094 16.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ADK PF00406.22 KXS10809.1 - 0.015 15.4 0.0 0.062 13.4 0.0 1.8 2 0 0 2 2 2 0 Adenylate kinase AAA_5 PF07728.14 KXS10809.1 - 0.016 15.2 0.0 0.029 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.12 KXS10809.1 - 0.023 14.0 0.0 0.051 12.9 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin KTI12 PF08433.10 KXS10809.1 - 0.027 14.0 0.0 0.049 13.1 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 RNA_helicase PF00910.22 KXS10809.1 - 0.029 14.8 0.0 0.055 13.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_19 PF13245.6 KXS10809.1 - 0.037 14.4 2.0 0.075 13.4 0.2 2.0 1 1 1 2 2 2 0 AAA domain IstB_IS21 PF01695.17 KXS10809.1 - 0.037 13.7 0.0 0.061 13.0 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein dNK PF01712.19 KXS10809.1 - 0.041 13.7 0.0 4.5 7.1 0.0 2.1 2 0 0 2 2 2 0 Deoxynucleoside kinase MeaB PF03308.16 KXS10809.1 - 0.043 12.8 0.4 0.088 11.8 0.2 1.6 1 1 1 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF2075 PF09848.9 KXS10809.1 - 0.049 12.9 0.0 0.08 12.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_24 PF13479.6 KXS10809.1 - 0.056 13.2 0.0 0.14 11.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KXS10809.1 - 0.068 12.9 0.9 0.15 11.8 0.3 1.8 1 1 1 2 2 2 0 AAA domain NTPase_1 PF03266.15 KXS10809.1 - 0.08 12.9 0.1 0.18 11.7 0.0 1.6 2 0 0 2 2 2 0 NTPase TrwB_AAD_bind PF10412.9 KXS10809.1 - 0.081 11.8 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_29 PF13555.6 KXS10809.1 - 0.082 12.7 0.1 0.14 11.9 0.1 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATPase PF06745.13 KXS10809.1 - 0.12 11.8 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 KaiC AAA_25 PF13481.6 KXS10809.1 - 0.13 11.8 1.9 0.58 9.7 1.9 2.0 1 1 0 1 1 1 0 AAA domain Phi_1 PF04674.12 KXS10810.1 - 3.9e-23 82.2 0.2 5.9e-23 81.6 0.2 1.3 1 0 0 1 1 1 1 Phosphate-induced protein 1 conserved region LRR_8 PF13855.6 KXS10810.1 - 0.018 14.8 1.0 0.095 12.5 1.0 2.2 1 1 0 1 1 1 0 Leucine rich repeat zf-CCCH_2 PF14608.6 KXS10811.1 - 1.7e-09 37.8 56.7 0.014 15.9 2.1 5.3 5 0 0 5 5 5 5 RNA-binding, Nab2-type zinc finger SpdB PF05122.13 KXS10811.1 - 1 9.6 11.8 0.34 11.1 1.4 3.5 3 0 0 3 3 3 0 Mobile element transfer protein VanZ PF04892.12 KXS10813.1 - 1.1e-05 26.1 0.0 2.2e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 VanZ like family DUF746 PF05344.11 KXS10814.1 - 0.14 12.0 0.1 0.74 9.7 0.0 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF746) PB1 PF00564.24 KXS10815.1 - 0.00017 21.5 0.0 0.00022 21.1 0.0 1.1 1 0 0 1 1 1 1 PB1 domain Mito_carr PF00153.27 KXS10816.1 - 7e-49 163.7 5.5 6e-18 64.6 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein ABC_membrane PF00664.23 KXS10818.1 - 1.7e-70 237.8 30.4 2.7e-40 138.8 9.5 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KXS10818.1 - 2.5e-54 183.5 0.0 6e-30 104.5 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_29 PF13555.6 KXS10818.1 - 1.7e-06 27.7 1.2 0.035 13.8 0.3 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KXS10818.1 - 2e-06 27.8 0.1 0.011 15.7 0.1 2.9 3 0 0 3 3 3 2 RsgA GTPase MMR_HSR1 PF01926.23 KXS10818.1 - 3.2e-06 27.2 0.8 0.11 12.6 0.2 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.23 KXS10818.1 - 3.8e-06 27.1 0.1 0.00046 20.3 0.0 2.6 2 0 0 2 2 2 1 Dynamin family AAA_16 PF13191.6 KXS10818.1 - 3.1e-05 24.4 0.1 0.086 13.2 0.0 3.0 2 1 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 KXS10818.1 - 3.3e-05 24.5 0.5 0.083 13.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 KXS10818.1 - 4.7e-05 22.8 1.0 0.0034 16.7 0.1 2.9 3 0 0 3 3 3 1 Zeta toxin SMC_N PF02463.19 KXS10818.1 - 8.6e-05 22.1 6.6 0.14 11.6 0.7 3.7 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain FtsK_SpoIIIE PF01580.18 KXS10818.1 - 0.00018 20.9 0.3 0.34 10.2 0.1 2.5 2 0 0 2 2 2 2 FtsK/SpoIIIE family T2SSE PF00437.20 KXS10818.1 - 0.00059 19.0 0.5 0.041 13.0 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein MeaB PF03308.16 KXS10818.1 - 0.0017 17.4 0.4 1.2 8.0 0.2 2.3 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_21 PF13304.6 KXS10818.1 - 0.0027 17.6 3.9 4.3 7.1 0.4 4.0 3 1 1 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system RNA_helicase PF00910.22 KXS10818.1 - 0.0028 18.0 0.2 2.3 8.6 0.0 3.2 3 0 0 3 3 2 1 RNA helicase AAA_25 PF13481.6 KXS10818.1 - 0.003 17.2 0.4 2.6 7.6 0.0 3.0 3 0 0 3 3 2 1 AAA domain cobW PF02492.19 KXS10818.1 - 0.0085 15.7 1.3 0.8 9.3 0.1 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 KXS10818.1 - 0.0086 15.6 0.1 1.6 8.2 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_22 PF13401.6 KXS10818.1 - 0.011 16.0 5.7 2.2 8.6 0.1 3.5 4 0 0 4 4 3 0 AAA domain KAP_NTPase PF07693.14 KXS10818.1 - 0.016 14.5 0.0 0.84 8.8 0.0 2.4 2 0 0 2 2 2 0 KAP family P-loop domain AAA_33 PF13671.6 KXS10818.1 - 0.025 14.7 2.3 4.1 7.5 0.1 3.1 3 0 0 3 3 2 0 AAA domain AAA_18 PF13238.6 KXS10818.1 - 0.027 15.0 0.1 9.5 6.8 0.1 2.9 3 0 0 3 3 2 0 AAA domain NACHT PF05729.12 KXS10818.1 - 0.032 14.2 0.9 5.9 6.8 0.2 2.6 2 0 0 2 2 2 0 NACHT domain AAA PF00004.29 KXS10818.1 - 0.048 14.1 0.0 1.3 9.4 0.1 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 KXS10818.1 - 0.059 12.5 0.0 1.1 8.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_24 PF13479.6 KXS10818.1 - 0.12 12.1 0.1 0.51 10.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain GTP_EFTU PF00009.27 KXS10818.1 - 0.12 11.9 0.1 17 4.9 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_15 PF13175.6 KXS10818.1 - 0.14 11.9 0.3 7.5 6.1 0.3 2.2 2 0 0 2 2 2 0 AAA ATPase domain NB-ARC PF00931.22 KXS10818.1 - 0.15 11.2 0.5 7.5 5.7 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain DUF2075 PF09848.9 KXS10818.1 - 0.16 11.2 0.4 5.2 6.2 0.1 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Septin PF00735.18 KXS10818.1 - 0.17 11.2 0.1 20 4.4 0.1 2.3 2 0 0 2 2 2 0 Septin AAA_30 PF13604.6 KXS10818.1 - 0.27 10.9 3.8 12 5.6 0.2 3.5 4 0 0 4 4 3 0 AAA domain PIF1 PF05970.14 KXS10818.1 - 0.29 10.2 3.0 0.19 10.8 0.1 2.1 3 0 0 3 3 2 0 PIF1-like helicase DUF87 PF01935.17 KXS10818.1 - 0.61 10.1 4.3 0.67 10.0 0.1 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain Peptidase_M20 PF01546.28 KXS10819.1 - 5.6e-33 114.4 0.0 8e-33 113.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KXS10819.1 - 2.2e-13 50.1 0.0 4.1e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KXS10819.1 - 0.0015 18.3 0.0 0.0027 17.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Ank_2 PF12796.7 KXS10820.1 - 0.00082 19.9 0.0 0.0016 19.0 0.0 1.5 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXS10820.1 - 0.17 12.2 0.0 0.39 11.1 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXS10821.1 - 0.017 15.7 0.1 0.034 14.8 0.1 1.5 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXS10821.1 - 0.083 13.5 0.0 0.13 12.9 0.0 1.3 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) FAD_binding_3 PF01494.19 KXS10822.1 - 4.4e-21 75.5 0.1 7.7e-12 45.1 0.0 2.9 2 1 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 KXS10822.1 - 5.4e-09 35.7 0.0 2.3e-05 23.8 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXS10822.1 - 8.8e-07 28.8 0.1 0.0015 18.2 0.1 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.14 KXS10822.1 - 2.6e-06 26.4 0.2 0.00037 19.3 0.1 2.2 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_3 PF13738.6 KXS10822.1 - 7.6e-06 25.4 0.1 0.083 12.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXS10822.1 - 1.7e-05 24.9 0.0 4.4e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KXS10822.1 - 9.8e-05 21.6 0.5 0.00019 20.6 0.2 1.6 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 KXS10822.1 - 0.00014 21.4 0.6 0.00071 19.0 0.1 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KXS10822.1 - 0.00024 21.6 0.0 0.49 11.0 0.0 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KXS10822.1 - 0.00046 19.4 0.1 0.0013 17.9 0.0 1.6 2 0 0 2 2 2 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 KXS10822.1 - 0.0036 16.4 0.0 1.4 7.9 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein Amino_oxidase PF01593.24 KXS10822.1 - 0.013 14.9 0.1 2.5 7.3 0.0 2.3 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Trp_halogenase PF04820.14 KXS10822.1 - 0.019 13.8 0.1 0.14 11.0 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase SE PF08491.10 KXS10822.1 - 0.072 12.1 0.0 0.18 10.8 0.0 1.6 2 0 0 2 2 2 0 Squalene epoxidase NAD_binding_9 PF13454.6 KXS10822.1 - 0.08 12.9 0.1 7.2 6.6 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding NAD_binding_7 PF13241.6 KXS10822.1 - 0.097 13.1 0.0 0.21 12.1 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Ank_3 PF13606.6 KXS10823.1 - 4.3e-05 23.6 0.0 0.00058 20.1 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 KXS10823.1 - 9.4e-05 22.6 0.0 0.0028 17.9 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXS10823.1 - 0.0003 21.3 0.0 0.00062 20.3 0.0 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KXS10823.1 - 0.0017 18.7 0.0 0.0041 17.5 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeat Ank_4 PF13637.6 KXS10823.1 - 0.0032 18.0 0.0 0.33 11.6 0.0 2.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Methyltransf_25 PF13649.6 KXS10824.1 - 5.3e-09 36.7 0.0 3.1e-08 34.2 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXS10824.1 - 9.4e-09 35.9 0.0 3.6e-08 34.1 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXS10824.1 - 8.1e-08 32.3 0.0 1.1e-07 31.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXS10824.1 - 9.9e-08 32.5 0.0 3.2e-07 30.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXS10824.1 - 5.1e-07 29.6 0.0 1.1e-06 28.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXS10824.1 - 0.005 16.4 0.0 0.0096 15.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 KXS10824.1 - 0.052 12.9 0.1 0.072 12.5 0.1 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 KXS10824.1 - 0.053 13.5 0.0 0.075 13.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.17 KXS10824.1 - 0.19 11.1 0.0 0.3 10.6 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Glyco_hydro_18 PF00704.28 KXS10825.1 - 4.4e-41 141.6 0.3 5.3e-41 141.4 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Ribosomal_S11 PF00411.19 KXS10825.1 - 0.21 12.0 0.0 0.36 11.2 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein S11 Redoxin PF08534.10 KXS10826.1 - 1.4e-15 57.3 0.0 2.2e-15 56.7 0.0 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 KXS10826.1 - 2.1e-14 53.5 0.0 2.9e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 KXS10826.1 - 4.6e-14 52.5 0.0 7.7e-14 51.8 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.20 KXS10826.1 - 6.5e-09 35.7 0.1 2.6e-08 33.8 0.1 1.9 1 1 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.6 KXS10826.1 - 0.0012 19.2 0.0 0.002 18.5 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain Armet PF10208.9 KXS10826.1 - 0.002 18.1 0.5 0.0033 17.4 0.1 1.6 2 0 0 2 2 2 1 Degradation arginine-rich protein for mis-folding Thioredoxin_9 PF14595.6 KXS10826.1 - 0.03 14.1 0.0 0.27 11.0 0.1 2.0 1 1 1 2 2 2 0 Thioredoxin DUF899 PF05988.12 KXS10826.1 - 0.1 12.1 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF899) Abhydrolase_9_N PF15420.6 KXS10829.1 - 0.00077 19.5 2.6 0.63 10.0 0.0 2.2 2 0 0 2 2 2 2 Alpha/beta-hydrolase family N-terminus FANCI_S4 PF14678.6 KXS10830.1 - 1.2e-31 109.7 0.3 1.1e-29 103.3 0.0 3.2 3 0 0 3 3 3 1 FANCI solenoid 4 FANCI_HD2 PF14680.6 KXS10830.1 - 1.6e-30 106.1 0.0 1.9e-29 102.6 0.0 2.9 4 0 0 4 4 4 1 FANCI helical domain 2 FANCI_S2 PF14676.6 KXS10830.1 - 2.3e-24 86.6 1.5 5.1e-23 82.2 0.1 3.3 2 1 1 3 3 3 1 FANCI solenoid 2 FANCI_S1 PF14675.6 KXS10830.1 - 1.2e-18 67.6 0.0 3.9e-18 65.8 0.0 1.9 1 0 0 1 1 1 1 FANCI solenoid 1 FANCI_HD1 PF14679.6 KXS10830.1 - 3.9e-10 39.6 0.1 2e-09 37.3 0.0 2.3 2 0 0 2 2 2 1 FANCI helical domain 1 Ric8 PF10165.9 KXS10830.1 - 0.0011 18.1 8.4 0.002 17.2 1.5 3.3 4 1 0 4 4 4 1 Guanine nucleotide exchange factor synembryn CRAL_TRIO PF00650.20 KXS10831.1 - 0.049 13.3 0.0 0.057 13.1 0.0 1.1 1 0 0 1 1 1 0 CRAL/TRIO domain Pkinase_Tyr PF07714.17 KXS10833.1 - 8.4e-73 244.8 0.0 9.8e-47 159.4 0.0 3.0 2 1 1 3 3 3 2 Protein tyrosine kinase Pkinase PF00069.25 KXS10833.1 - 5.2e-56 189.9 0.0 8.4e-36 123.7 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Kinase-like PF14531.6 KXS10833.1 - 4.7e-06 26.1 0.0 0.00072 19.0 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 KXS10833.1 - 0.00075 18.9 0.1 0.55 9.5 0.0 2.2 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family SH3_9 PF14604.6 KXS10833.1 - 0.0031 17.3 0.0 0.0059 16.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KXS10833.1 - 0.0053 16.4 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain APH PF01636.23 KXS10833.1 - 0.0086 16.0 0.0 0.026 14.5 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 KXS10833.1 - 0.024 14.2 0.0 0.045 13.4 0.0 1.3 1 0 0 1 1 1 0 RIO1 family SH3_1 PF00018.28 KXS10833.1 - 0.026 14.1 0.0 0.049 13.3 0.0 1.5 1 0 0 1 1 1 0 SH3 domain HET PF06985.11 KXS10834.1 - 3.6e-22 79.3 0.6 5.8e-22 78.6 0.6 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DZR PF12773.7 KXS10834.1 - 0.3 11.1 1.8 0.97 9.5 0.1 2.2 2 0 0 2 2 2 0 Double zinc ribbon DUF4494 PF14902.6 KXS10835.1 - 0.031 14.1 0.4 0.046 13.6 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4494) TMEM247 PF15444.6 KXS10835.1 - 0.069 13.2 0.4 0.085 12.9 0.4 1.2 1 0 0 1 1 1 0 Transmembrane protein 247 DDE_Tnp_4 PF13359.6 KXS10836.1 - 2.5e-09 37.0 0.0 2.8e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF3987 PF13148.6 KXS10838.1 - 0.17 10.9 0.0 0.2 10.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Sel1 PF08238.12 KXS10839.1 - 7.2e-35 118.6 29.2 1.8e-06 28.4 0.0 7.7 7 1 0 7 7 7 7 Sel1 repeat TPR_2 PF07719.17 KXS10839.1 - 0.077 13.1 11.5 1.2 9.5 0.0 5.3 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_11 PF13414.6 KXS10839.1 - 1.6 8.5 7.7 1.1 9.0 0.1 4.3 6 0 0 6 6 6 0 TPR repeat TPR_17 PF13431.6 KXS10839.1 - 1.9 9.1 3.6 62 4.3 0.1 4.2 4 1 0 4 4 4 0 Tetratricopeptide repeat HNH_repeat PF18780.1 KXS10839.1 - 5.1 7.0 4.6 46 4.0 0.2 3.2 3 0 0 3 3 3 0 Homing endonuclease repeat TPR_1 PF00515.28 KXS10839.1 - 6.7 6.7 9.5 49 4.0 0.1 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat LRR_6 PF13516.6 KXS10840.1 - 3.6e-15 54.6 3.4 0.0002 21.1 0.1 4.4 4 0 0 4 4 4 4 Leucine Rich repeat HOASN PF14515.6 KXS10840.1 - 0.0026 18.1 0.6 9.1 6.7 0.0 3.2 1 1 2 3 3 3 2 Haem-oxygenase-associated N-terminal helices FumaraseC_C PF10415.9 KXS10840.1 - 0.026 14.9 0.3 5.1 7.6 0.0 3.0 1 1 2 3 3 3 0 Fumarase C C-terminus Arm-DNA-bind_1 PF09003.10 KXS10840.1 - 0.03 14.4 0.4 18 5.6 0.0 3.1 1 1 2 3 3 3 0 Bacteriophage lambda integrase, Arm DNA-binding domain Ank_2 PF12796.7 KXS10844.1 - 4.3e-20 72.1 0.0 2.3e-10 40.9 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXS10844.1 - 3.4e-11 43.1 0.9 3e-06 27.4 0.2 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KXS10844.1 - 5.2e-09 36.1 0.0 0.00012 22.4 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 KXS10844.1 - 2.6e-08 33.5 0.0 9.8e-05 22.5 0.0 3.4 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 KXS10844.1 - 2.7e-07 31.0 0.1 4.4e-06 27.1 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Cnd1_N PF12922.7 KXS10844.1 - 0.15 11.9 0.2 0.3 10.9 0.2 1.5 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1, N-term Spt5_N PF11942.8 KXS10844.1 - 1.5 9.8 8.9 0.16 13.0 3.0 2.3 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Pkinase PF00069.25 KXS10845.1 - 3.1e-41 141.5 0.0 7.6e-41 140.2 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS10845.1 - 3.7e-37 128.0 0.0 3.4e-32 111.8 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Sel1 PF08238.12 KXS10845.1 - 7.7e-31 105.9 15.9 5.1e-06 27.0 0.4 5.4 5 0 0 5 5 5 5 Sel1 repeat Pkinase_fungal PF17667.1 KXS10845.1 - 1.2e-06 27.6 0.0 1.9e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KXS10845.1 - 0.00035 20.6 0.3 0.00074 19.5 0.1 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KXS10845.1 - 0.0058 16.0 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KXS10845.1 - 0.038 13.3 0.0 0.069 12.4 0.0 1.3 1 0 0 1 1 1 0 Kinase-like L31 PF09784.9 KXS10845.1 - 0.18 12.2 0.1 0.37 11.3 0.1 1.5 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L31 AAA PF00004.29 KXS10846.1 - 7.3e-16 58.8 0.0 1.8e-15 57.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KXS10846.1 - 0.00014 21.9 0.0 0.00027 21.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KXS10846.1 - 0.00052 20.3 0.3 0.0064 16.8 0.1 2.2 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 KXS10846.1 - 0.0015 18.9 0.0 0.003 18.0 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 KXS10846.1 - 0.016 15.0 0.2 0.038 13.7 0.2 1.7 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KXS10846.1 - 0.018 14.4 0.1 0.038 13.4 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ATPase PF06745.13 KXS10846.1 - 0.028 13.8 0.0 0.083 12.2 0.0 1.7 1 1 0 1 1 1 0 KaiC AAA_19 PF13245.6 KXS10846.1 - 0.029 14.7 0.0 0.06 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zot PF05707.12 KXS10846.1 - 0.083 12.5 0.0 7.9 6.1 0.0 2.2 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) AAA_11 PF13086.6 KXS10846.1 - 0.09 12.5 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF4505 PF14956.6 KXS10846.1 - 0.098 12.4 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4505) TIP49 PF06068.13 KXS10846.1 - 0.1 11.8 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_2 PF07724.14 KXS10846.1 - 0.11 12.6 0.0 0.3 11.2 0.0 1.5 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_28 PF13521.6 KXS10846.1 - 0.11 12.7 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KXS10846.1 - 0.12 12.5 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KXS10846.1 - 0.16 11.5 0.4 0.44 10.1 0.4 1.9 1 1 0 1 1 1 0 AAA domain Vps36_ESCRT-II PF11605.8 KXS10846.1 - 0.18 12.0 0.0 0.43 10.8 0.0 1.6 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 DUF2075 PF09848.9 KXS10846.1 - 0.23 10.6 0.0 0.4 9.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DOMON PF03351.17 KXS10847.1 - 6.2e-09 36.1 0.1 9.4e-09 35.5 0.1 1.2 1 0 0 1 1 1 1 DOMON domain CDH-cyt PF16010.5 KXS10847.1 - 4.2e-07 29.8 0.0 5.8e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase Aminotran_3 PF00202.21 KXS10849.1 - 2e-40 138.7 0.0 2e-38 132.2 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class-III Oxidored_molyb PF00174.19 KXS10851.1 - 1.3e-57 194.2 0.0 2.3e-57 193.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 KXS10851.1 - 4.4e-36 123.9 0.1 7.7e-36 123.1 0.1 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Cyt-b5 PF00173.28 KXS10851.1 - 1.9e-18 66.3 0.0 3.6e-18 65.5 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain BNR PF02012.20 KXS10851.1 - 0.075 13.1 0.0 0.55 10.5 0.0 2.6 1 0 0 1 1 1 0 BNR/Asp-box repeat BCS1_N PF08740.11 KXS10852.1 - 2.8e-50 170.9 0.4 3.8e-50 170.5 0.4 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 KXS10852.1 - 5e-19 69.0 0.0 8e-19 68.4 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KXS10852.1 - 0.0063 16.9 0.7 0.075 13.4 0.4 2.5 2 1 1 3 3 3 1 AAA ATPase domain AAA_24 PF13479.6 KXS10852.1 - 0.033 13.9 0.0 0.071 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 KXS10852.1 - 0.037 13.4 0.0 0.062 12.6 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_18 PF13238.6 KXS10852.1 - 0.037 14.6 0.0 0.069 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 KXS10852.1 - 0.084 12.0 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_25 PF13481.6 KXS10852.1 - 0.089 12.4 0.0 0.28 10.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF4964 PF16334.5 KXS10852.1 - 0.16 11.5 0.3 0.44 10.1 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4964) Viral_helicase1 PF01443.18 KXS10852.1 - 0.2 11.4 0.0 0.4 10.4 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Oxysterol_BP PF01237.18 KXS10853.1 - 3.7e-80 269.6 0.0 5.3e-72 242.7 0.0 2.0 1 1 1 2 2 2 2 Oxysterol-binding protein TPR_1 PF00515.28 KXS10855.1 - 2e-61 201.5 26.3 2.4e-08 33.4 0.1 10.8 11 1 0 11 11 10 9 Tetratricopeptide repeat TPR_2 PF07719.17 KXS10855.1 - 3e-52 170.6 23.8 1.8e-06 27.6 0.0 10.2 11 0 0 11 11 10 9 Tetratricopeptide repeat TPR_8 PF13181.6 KXS10855.1 - 8.5e-42 137.9 17.5 7.9e-05 22.6 0.0 10.9 10 1 0 10 10 10 8 Tetratricopeptide repeat TPR_16 PF13432.6 KXS10855.1 - 5.7e-34 116.5 13.2 3.3e-06 27.6 0.0 6.4 4 2 2 6 6 6 6 Tetratricopeptide repeat TPR_17 PF13431.6 KXS10855.1 - 5.1e-33 111.1 20.1 0.00094 19.4 0.1 10.4 10 1 1 11 11 10 7 Tetratricopeptide repeat TPR_14 PF13428.6 KXS10855.1 - 6e-33 110.7 16.8 5.1e-06 26.9 0.0 9.5 3 3 7 10 10 10 8 Tetratricopeptide repeat TPR_19 PF14559.6 KXS10855.1 - 4.1e-29 100.9 16.4 2.4e-06 28.0 0.3 7.0 4 1 3 7 7 7 7 Tetratricopeptide repeat TPR_11 PF13414.6 KXS10855.1 - 7.6e-26 89.5 30.6 1.8e-05 24.3 1.5 10.2 4 3 6 10 10 10 6 TPR repeat TPR_12 PF13424.6 KXS10855.1 - 1.6e-25 89.2 25.6 9.8e-05 22.6 1.0 7.8 4 3 3 7 7 7 7 Tetratricopeptide repeat TPR_6 PF13174.6 KXS10855.1 - 7.2e-25 85.9 21.4 0.0053 17.3 0.0 9.8 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_7 PF13176.6 KXS10855.1 - 2.4e-24 83.5 13.9 0.035 14.1 0.0 9.9 10 1 0 10 10 10 7 Tetratricopeptide repeat TPR_9 PF13371.6 KXS10855.1 - 7.2e-19 67.7 15.0 0.0018 18.4 0.2 6.9 3 2 5 8 8 8 7 Tetratricopeptide repeat TPR_15 PF13429.6 KXS10855.1 - 3.4e-12 46.1 8.7 0.015 14.5 0.0 5.8 1 1 4 5 5 5 4 Tetratricopeptide repeat TPR_21 PF09976.9 KXS10855.1 - 7e-11 42.2 5.5 0.00087 19.0 0.1 4.7 4 2 1 5 5 5 2 Tetratricopeptide repeat-like domain ANAPC3 PF12895.7 KXS10855.1 - 1.2e-09 38.3 12.5 3.7e-06 27.1 0.7 4.3 3 1 3 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_MalT PF17874.1 KXS10855.1 - 5.2e-06 26.1 3.9 2 7.7 0.1 3.9 2 1 1 4 4 3 2 MalT-like TPR region TPR_10 PF13374.6 KXS10855.1 - 5.5e-05 22.9 19.6 3.7 7.5 0.0 8.1 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_20 PF14561.6 KXS10855.1 - 6.1e-05 23.3 3.0 1.9 8.9 0.0 5.1 3 2 2 6 6 6 2 Tetratricopeptide repeat DUF2225 PF09986.9 KXS10855.1 - 0.00016 21.5 1.9 0.11 12.3 0.1 3.4 1 1 1 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2225) ChAPs PF09295.10 KXS10855.1 - 0.00065 18.8 2.4 0.016 14.2 0.1 2.9 3 0 0 3 3 3 1 ChAPs (Chs5p-Arf1p-binding proteins) Fis1_TPR_C PF14853.6 KXS10855.1 - 0.00075 19.5 5.2 11 6.1 0.0 6.1 6 1 1 7 7 7 0 Fis1 C-terminal tetratricopeptide repeat SNAP PF14938.6 KXS10855.1 - 0.0023 17.4 15.3 1.4 8.3 2.1 5.4 2 2 3 5 5 5 1 Soluble NSF attachment protein, SNAP Tcf25 PF04910.14 KXS10855.1 - 0.0083 15.2 1.8 0.21 10.6 0.0 3.1 3 1 0 3 3 3 1 Transcriptional repressor TCF25 DUF4919 PF16266.5 KXS10855.1 - 0.065 13.2 0.1 16 5.4 0.0 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4919) DUF1824 PF08854.10 KXS10855.1 - 0.12 12.3 0.5 1.3 8.9 0.1 2.7 3 1 1 4 4 3 0 Domain of unknown function (DUF1824) BTAD PF03704.17 KXS10855.1 - 0.38 11.2 8.2 23 5.4 0.0 3.5 3 1 0 3 3 3 0 Bacterial transcriptional activator domain TOM20_plant PF06552.12 KXS10855.1 - 0.6 9.8 3.4 14 5.3 0.7 4.0 4 1 0 4 4 4 0 Plant specific mitochondrial import receptor subunit TOM20 TipAS PF07739.13 KXS10855.1 - 0.64 10.6 5.2 1.2 9.7 0.3 3.3 3 1 0 3 3 3 0 TipAS antibiotic-recognition domain TPR_3 PF07720.12 KXS10855.1 - 1.6 8.8 29.4 8.1 6.5 2.9 7.1 8 0 0 8 8 7 0 Tetratricopeptide repeat MIT PF04212.18 KXS10855.1 - 1.8 8.7 22.2 24 5.1 0.3 6.6 8 0 0 8 8 6 0 MIT (microtubule interacting and transport) domain APP_E2 PF12925.7 KXS10855.1 - 2.5 7.8 4.9 14 5.3 0.0 3.5 4 2 0 4 4 3 0 E2 domain of amyloid precursor protein GrpE PF01025.19 KXS10856.1 - 8.8e-45 152.3 0.2 1.1e-44 152.0 0.2 1.1 1 0 0 1 1 1 1 GrpE DUF812 PF05667.11 KXS10856.1 - 0.0012 17.8 0.1 0.0015 17.6 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF812) NPH3 PF03000.14 KXS10856.1 - 0.011 15.4 0.2 0.015 14.9 0.2 1.1 1 0 0 1 1 1 0 NPH3 family PBP_sp32 PF07222.12 KXS10856.1 - 0.03 13.8 0.5 0.058 12.8 0.5 1.5 2 0 0 2 2 2 0 Proacrosin binding protein sp32 DUF4407 PF14362.6 KXS10856.1 - 0.047 13.0 1.0 0.06 12.7 1.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TPD52 PF04201.15 KXS10856.1 - 0.065 12.8 1.6 0.095 12.3 1.6 1.2 1 0 0 1 1 1 0 Tumour protein D52 family Glu-tRNAGln PF02686.15 KXS10856.1 - 0.068 13.5 0.2 1.7 9.0 0.2 2.3 1 1 0 1 1 1 0 Glu-tRNAGln amidotransferase C subunit Cnn_1N PF07989.11 KXS10856.1 - 0.086 13.0 0.4 0.16 12.1 0.4 1.5 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 Atg14 PF10186.9 KXS10856.1 - 0.1 11.7 0.5 0.13 11.4 0.5 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TSC22 PF01166.18 KXS10856.1 - 0.12 12.6 1.5 0.25 11.7 1.5 1.5 1 0 0 1 1 1 0 TSC-22/dip/bun family DUF3412 PF11892.8 KXS10856.1 - 0.13 12.3 0.2 0.21 11.7 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3412) Prominin PF05478.11 KXS10856.1 - 0.16 9.9 0.2 0.21 9.5 0.2 1.0 1 0 0 1 1 1 0 Prominin HIP1_clath_bdg PF16515.5 KXS10856.1 - 0.76 10.4 7.2 6.1 7.5 3.0 2.2 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 APG6_N PF17675.1 KXS10856.1 - 0.87 10.1 5.4 1.2 9.7 5.4 1.1 1 0 0 1 1 1 0 Apg6 coiled-coil region COG2 PF06148.11 KXS10856.1 - 2.7 8.1 5.4 5.8 7.0 5.4 1.6 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 DivIC PF04977.15 KXS10856.1 - 3.1 7.6 6.9 4.8 7.0 6.5 1.5 1 1 0 1 1 1 0 Septum formation initiator tRNA-synt_2d PF01409.20 KXS10857.1 - 5.2e-44 150.6 1.3 1.1e-24 87.3 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 KXS10857.1 - 1.9e-21 76.3 0.1 3.9e-21 75.3 0.1 1.6 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain HMG_box PF00505.19 KXS10858.1 - 3.9e-09 36.8 1.0 9.7e-09 35.5 1.0 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KXS10858.1 - 2.1e-08 34.6 0.6 5.6e-08 33.3 0.6 1.8 1 0 0 1 1 1 1 HMG-box domain DUF1912 PF08930.10 KXS10858.1 - 0.017 15.3 0.7 0.034 14.3 0.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1912) TPR_1 PF00515.28 KXS10859.1 - 3e-29 99.6 2.7 8.3e-05 22.2 0.0 13.2 13 0 0 13 13 13 5 Tetratricopeptide repeat TPR_2 PF07719.17 KXS10859.1 - 5.2e-28 94.9 38.4 0.00013 21.8 0.0 17.5 21 0 0 21 21 18 6 Tetratricopeptide repeat TPR_19 PF14559.6 KXS10859.1 - 5.5e-27 94.1 50.9 0.00057 20.3 0.1 13.4 12 1 1 13 13 13 7 Tetratricopeptide repeat TPR_11 PF13414.6 KXS10859.1 - 6e-26 89.9 12.2 8.8e-07 28.5 0.1 13.8 12 2 2 14 14 14 4 TPR repeat TPR_8 PF13181.6 KXS10859.1 - 8.8e-22 75.5 8.9 0.0042 17.2 0.0 13.8 15 0 0 15 15 14 4 Tetratricopeptide repeat TPR_17 PF13431.6 KXS10859.1 - 6.2e-21 73.2 6.9 0.041 14.3 0.0 12.7 14 0 0 14 14 12 4 Tetratricopeptide repeat TPR_14 PF13428.6 KXS10859.1 - 1.5e-17 62.8 66.8 0.0056 17.4 0.2 18.3 13 4 7 20 20 18 6 Tetratricopeptide repeat TPR_16 PF13432.6 KXS10859.1 - 9.4e-16 58.2 89.2 3e-06 27.8 0.4 14.9 12 2 3 16 16 15 8 Tetratricopeptide repeat TPR_12 PF13424.6 KXS10859.1 - 1.4e-06 28.4 60.0 0.0093 16.2 0.0 15.2 12 4 5 17 17 15 4 Tetratricopeptide repeat TPR_7 PF13176.6 KXS10859.1 - 1.6e-05 24.6 24.2 1.4 9.1 0.1 10.3 11 0 0 11 11 11 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KXS10859.1 - 4.4e-05 23.6 8.5 0.049 13.9 0.0 6.8 7 1 0 7 7 7 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 KXS10859.1 - 0.00015 21.8 39.3 0.0048 17.0 0.4 9.6 10 0 0 10 10 10 3 Tetratricopeptide repeat NARP1 PF12569.8 KXS10859.1 - 0.00063 18.8 0.8 0.0046 15.9 0.0 2.6 3 0 0 3 3 3 1 NMDA receptor-regulated protein 1 TPR_6 PF13174.6 KXS10859.1 - 0.0083 16.7 29.2 56 4.7 0.0 12.9 14 0 0 14 14 12 0 Tetratricopeptide repeat Sel1 PF08238.12 KXS10859.1 - 0.021 15.5 1.3 24 5.8 0.1 4.9 4 0 0 4 4 4 0 Sel1 repeat Alkyl_sulf_dimr PF14863.6 KXS10859.1 - 3.3 8.2 8.8 5.7 7.4 0.4 4.7 4 1 0 4 4 4 0 Alkyl sulfatase dimerisation DHHC PF01529.20 KXS10860.1 - 1.4e-36 125.6 6.3 1.4e-36 125.6 6.3 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase Lactamase_B PF00753.27 KXS10861.1 - 2.5e-26 92.9 0.5 3.2e-26 92.6 0.5 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KXS10861.1 - 0.00071 19.1 0.5 0.0018 17.8 0.5 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain ImpA_N PF06812.12 KXS10864.1 - 0.12 12.5 0.0 0.3 11.2 0.0 1.7 1 0 0 1 1 1 0 ImpA, N-terminal, type VI secretion system Glyco_hydro_11 PF00457.17 KXS10864.1 - 0.17 11.5 0.0 0.37 10.4 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolases family 11 CTC1 PF15489.6 KXS10865.1 - 2.3e-23 81.8 0.0 6.8e-12 43.8 0.0 3.3 3 0 0 3 3 3 3 CST, telomere maintenance, complex subunit CTC1 tRNA_anti-codon PF01336.25 KXS10865.1 - 9e-05 22.4 0.8 7.8 6.6 0.0 5.3 6 0 0 6 6 6 2 OB-fold nucleic acid binding domain PEPCK_GTP PF00821.18 KXS10866.1 - 2.5e-161 536.5 0.0 3e-161 536.2 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain PEPCK_N PF17297.2 KXS10866.1 - 2.2e-89 298.8 0.0 2.9e-89 298.4 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase N-terminal domain ICA69 PF04629.14 KXS10867.1 - 0.061 13.6 0.9 0.091 13.1 0.9 1.2 1 0 0 1 1 1 0 Islet cell autoantigen ICA69, C-terminal domain TYA PF01021.19 KXS10867.1 - 4 7.8 7.2 16 5.9 5.9 2.4 2 1 0 2 2 2 0 TYA transposon protein Pyr_redox_2 PF07992.14 KXS10868.1 - 4.7e-38 131.1 0.8 7.6e-38 130.4 0.8 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.6 KXS10868.1 - 7.7e-22 77.2 0.0 2.6e-21 75.5 0.0 2.0 2 0 0 2 2 2 1 Rieske-like [2Fe-2S] domain NIR_SIR PF01077.22 KXS10868.1 - 1e-18 67.4 0.0 1.7e-18 66.6 0.0 1.3 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Pyr_redox PF00070.27 KXS10868.1 - 5.1e-16 59.0 0.2 3.1e-14 53.3 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Fer2_BFD PF04324.15 KXS10868.1 - 6.1e-16 58.5 7.4 6.3e-11 42.5 6.0 2.7 2 0 0 2 2 2 2 BFD-like [2Fe-2S] binding domain Rieske PF00355.26 KXS10868.1 - 7.4e-12 45.1 0.0 2.2e-11 43.5 0.0 1.9 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain NIR_SIR_ferr PF03460.17 KXS10868.1 - 1.4e-10 40.9 0.0 4.9e-10 39.1 0.0 2.0 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Rubredoxin_C PF18267.1 KXS10868.1 - 9.5e-05 22.2 0.0 0.00029 20.7 0.0 1.9 1 0 0 1 1 1 1 Rubredoxin NAD+ reductase C-terminal domain GIDA PF01134.22 KXS10868.1 - 0.00026 20.2 1.0 0.013 14.6 0.5 2.4 2 0 0 2 2 2 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 KXS10868.1 - 0.0021 17.4 0.3 0.037 13.3 0.1 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.6 KXS10868.1 - 0.021 14.8 2.8 1.7 8.6 0.1 3.3 2 1 1 3 3 3 0 FAD-NAD(P)-binding TrkA_N PF02254.18 KXS10868.1 - 0.043 14.1 0.1 9.6 6.5 0.0 2.6 2 0 0 2 2 2 0 TrkA-N domain NAD_binding_8 PF13450.6 KXS10868.1 - 0.11 12.7 0.1 0.59 10.4 0.1 2.3 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Rxt3 PF08642.10 KXS10871.1 - 2.3e-21 76.9 1.7 3.9e-20 72.9 0.0 2.9 2 1 0 2 2 2 1 Histone deacetylation protein Rxt3 LCCL PF03815.19 KXS10871.1 - 2.5e-05 24.3 0.0 0.00071 19.6 0.0 2.3 2 0 0 2 2 2 1 LCCL domain SPX PF03105.19 KXS10871.1 - 0.74 9.7 5.0 0.87 9.4 5.0 1.2 1 0 0 1 1 1 0 SPX domain TFIIA PF03153.13 KXS10871.1 - 7.9 6.4 12.6 11 5.9 12.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ribosomal_L15e PF00827.17 KXS10872.1 - 3.5e-85 284.6 8.0 3.5e-85 284.6 8.0 2.2 2 0 0 2 2 2 1 Ribosomal L15 VPS13 PF16908.5 KXS10872.1 - 4.1e-68 229.7 0.3 1.7e-66 224.4 0.0 3.7 5 0 0 5 5 5 1 Vacuolar sorting-associated protein 13, N-terminal VPS13_C PF16909.5 KXS10872.1 - 1.4e-64 217.1 3.8 1.8e-58 197.2 0.2 2.5 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal VPS13_mid_rpt PF16910.5 KXS10872.1 - 5.3e-57 193.0 1.7 2.4e-56 190.8 0.8 2.7 3 0 0 3 3 3 1 Repeating coiled region of VPS13 SHR-BD PF06650.12 KXS10872.1 - 1e-53 182.5 0.0 2.1e-26 92.9 0.0 3.4 3 0 0 3 3 3 2 SHR-binding domain of vacuolar-sorting associated protein 13 MORN PF02493.20 KXS10872.1 - 6.6e-43 142.1 50.7 1.1e-05 25.0 1.0 10.3 10 0 0 10 10 10 9 MORN repeat Chorein_N PF12624.7 KXS10872.1 - 6.3e-31 106.9 0.1 2.3e-30 105.1 0.1 2.0 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 DPM2 PF07297.12 KXS10872.1 - 1.9e-21 76.1 4.7 4.4e-21 75.0 4.7 1.6 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) CUE PF02845.16 KXS10872.1 - 8e-09 35.0 0.1 2e-08 33.7 0.1 1.7 1 0 0 1 1 1 1 CUE domain ATG_C PF09333.11 KXS10872.1 - 4e-07 30.3 0.1 1.3e-06 28.7 0.1 1.9 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain PIG-P PF08510.12 KXS10872.1 - 0.011 15.7 0.3 0.024 14.5 0.3 1.6 1 0 0 1 1 1 0 PIG-P ThiF PF00899.21 KXS10873.1 - 1.6e-64 217.6 0.0 2.5e-64 217.0 0.0 1.2 1 0 0 1 1 1 1 ThiF family UBA_e1_thiolCys PF10585.9 KXS10873.1 - 1.8e-14 54.3 0.0 8.6e-09 35.7 0.0 2.4 1 1 1 2 2 2 2 Ubiquitin-activating enzyme active site UAE_UbL PF14732.6 KXS10873.1 - 9.3e-10 39.0 5.0 2.4e-09 37.6 5.0 1.7 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain Shikimate_DH PF01488.20 KXS10873.1 - 0.0016 18.5 0.1 0.0034 17.5 0.1 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 KXS10873.1 - 0.023 15.1 0.0 0.06 13.8 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox PF00070.27 KXS10873.1 - 0.037 14.6 0.8 0.67 10.6 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Polysacc_synt_2 PF02719.15 KXS10873.1 - 0.12 11.5 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 KXS10873.1 - 0.14 12.4 0.1 0.35 11.1 0.1 1.7 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain zf-RING_2 PF13639.6 KXS10874.1 - 7.8e-12 45.3 5.4 1.1e-11 44.8 5.4 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KXS10874.1 - 9.6e-11 41.2 1.2 9.6e-11 41.2 1.2 1.9 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KXS10874.1 - 1.1e-08 34.7 5.0 1.7e-08 34.2 5.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KXS10874.1 - 1.9e-06 28.0 4.5 4.6e-06 26.8 4.5 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KXS10874.1 - 2.2e-06 27.4 2.3 3.3e-06 26.9 2.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXS10874.1 - 3.7e-06 26.8 2.2 5.5e-06 26.2 2.2 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KXS10874.1 - 3.1e-05 23.9 2.1 9.6e-05 22.3 0.7 2.2 1 1 1 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KXS10874.1 - 0.00089 19.1 2.5 0.0018 18.1 2.6 1.5 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KXS10874.1 - 0.0014 18.7 1.1 0.0029 17.6 1.1 1.5 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 KXS10874.1 - 0.002 18.0 2.4 0.0029 17.4 2.4 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) TauD PF02668.16 KXS10874.1 - 0.037 13.8 0.0 0.06 13.1 0.0 1.2 1 0 0 1 1 1 0 Taurine catabolism dioxygenase TauD, TfdA family zf-C3H2C3 PF17122.5 KXS10874.1 - 0.046 13.8 2.0 0.11 12.6 2.0 1.6 1 1 0 1 1 1 0 Zinc-finger Zn_ribbon_17 PF17120.5 KXS10874.1 - 0.16 11.6 2.5 0.32 10.7 2.5 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type PHD PF00628.29 KXS10874.1 - 0.34 10.8 3.2 0.78 9.7 3.3 1.6 1 1 0 1 1 1 0 PHD-finger zf-RING_4 PF14570.6 KXS10874.1 - 0.68 9.8 3.9 1.4 8.7 3.9 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 KXS10874.1 - 0.82 9.9 4.2 4.9 7.4 4.2 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain zf-HIT PF04438.16 KXS10877.1 - 1.8e-10 40.5 9.1 2.9e-10 39.8 9.1 1.4 1 0 0 1 1 1 1 HIT zinc finger STI1 PF17830.1 KXS10877.1 - 0.0056 16.6 0.1 0.019 14.9 0.0 1.9 2 1 0 3 3 3 1 STI1 domain zf-MYND PF01753.18 KXS10877.1 - 0.0081 16.2 4.2 0.014 15.5 4.2 1.3 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KXS10877.1 - 0.39 11.1 5.9 0.92 9.9 5.9 1.6 1 1 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Rz1 PF06085.11 KXS10877.1 - 6.6 6.6 9.5 7.5 6.4 1.0 2.7 3 0 0 3 3 3 0 Lipoprotein Rz1 precursor ParA PF10609.9 KXS10878.1 - 1.3e-98 329.3 0.0 1.6e-98 329.1 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KXS10878.1 - 1.4e-13 51.0 0.0 2.4e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 KXS10878.1 - 2.1e-07 31.0 0.0 3e-06 27.2 0.0 2.1 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.15 KXS10878.1 - 1.7e-06 27.5 0.7 5.8e-05 22.4 0.1 2.6 2 1 0 2 2 2 1 Anion-transporting ATPase Fer4_NifH PF00142.18 KXS10878.1 - 0.0011 18.5 0.0 0.29 10.5 0.0 2.4 2 1 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_25 PF13481.6 KXS10878.1 - 0.0024 17.5 0.0 0.0048 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_26 PF13500.6 KXS10878.1 - 0.0043 16.9 0.1 0.33 10.7 0.0 2.4 2 1 0 2 2 2 1 AAA domain MipZ PF09140.11 KXS10878.1 - 0.011 15.1 0.0 0.03 13.6 0.0 1.7 1 1 0 1 1 1 0 ATPase MipZ RsgA_GTPase PF03193.16 KXS10878.1 - 0.02 14.8 0.0 0.04 13.8 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase NB-ARC PF00931.22 KXS10878.1 - 0.022 14.0 0.0 0.038 13.2 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_16 PF13191.6 KXS10878.1 - 0.13 12.6 0.0 0.21 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.14 KXS10878.1 - 0.16 12.0 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 KXS10878.1 - 0.17 11.8 0.1 0.32 10.9 0.1 1.4 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.22 KXS10878.1 - 0.18 12.2 0.0 0.34 11.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase RRM_1 PF00076.22 KXS10879.1 - 5e-12 45.5 0.1 8.6e-12 44.7 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Torus PF16131.5 KXS10879.1 - 1.3e-08 35.5 0.2 2.9e-08 34.4 0.2 1.5 1 0 0 1 1 1 1 Torus domain zf_CCCH_4 PF18345.1 KXS10879.1 - 5.5e-07 29.4 3.7 1.7e-06 27.9 3.7 1.9 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 KXS10879.1 - 0.00014 21.7 2.2 0.00014 21.7 2.2 2.4 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 KXS10879.1 - 0.00036 20.7 0.1 0.00087 19.5 0.1 1.6 1 0 0 1 1 1 1 Zinc-finger containing family Nup35_RRM_2 PF14605.6 KXS10879.1 - 0.007 16.3 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif FYVE PF01363.21 KXS10879.1 - 0.0074 16.4 0.4 0.0074 16.4 0.4 1.8 2 0 0 2 2 2 1 FYVE zinc finger zf-CCCH_4 PF18044.1 KXS10879.1 - 0.027 14.3 3.6 0.027 14.3 3.6 2.0 2 0 0 2 2 2 0 CCCH-type zinc finger zf-CCCH_2 PF14608.6 KXS10879.1 - 0.034 14.6 1.9 0.034 14.6 1.9 2.4 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger ATP12 PF07542.11 KXS10880.1 - 8.6e-40 135.8 0.4 8.6e-40 135.8 0.4 1.6 2 0 0 2 2 2 1 ATP12 chaperone protein DUF3535 PF12054.8 KXS10880.1 - 0.055 12.7 0.0 0.067 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3535) SWIB PF02201.18 KXS10880.1 - 0.15 12.0 0.0 1.1 9.3 0.0 2.3 3 0 0 3 3 3 0 SWIB/MDM2 domain DUF2012 PF09430.10 KXS10881.1 - 1.6e-24 86.4 0.0 2.2e-24 85.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) Xan_ur_permease PF00860.20 KXS10882.1 - 3e-64 217.2 27.8 4.5e-64 216.6 27.8 1.1 1 0 0 1 1 1 1 Permease family FAD_binding_3 PF01494.19 KXS10883.1 - 1.6e-104 350.0 0.0 2e-104 349.6 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DUF1929 PF09118.11 KXS10883.1 - 0.0071 16.6 0.0 0.039 14.2 0.0 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF1929) FAD_binding_2 PF00890.24 KXS10883.1 - 0.095 11.8 0.1 4.7 6.2 0.0 2.8 3 0 0 3 3 3 0 FAD binding domain Ribosomal_L28 PF00830.19 KXS10884.1 - 3.6e-14 52.7 0.5 5.6e-14 52.1 0.5 1.3 1 0 0 1 1 1 1 Ribosomal L28 family WD40 PF00400.32 KXS10885.1 - 4.9e-09 36.7 13.0 0.0032 18.3 1.7 5.2 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXS10885.1 - 5e-07 29.9 0.1 0.01 16.2 0.1 2.8 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KXS10885.1 - 1.6e-05 24.9 0.0 4.4e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A EspG PF06872.11 KXS10885.1 - 0.044 12.4 0.0 0.066 11.8 0.0 1.1 1 0 0 1 1 1 0 EspG protein Brix PF04427.18 KXS10889.1 - 5.9e-32 111.3 0.0 7.7e-32 111.0 0.0 1.1 1 0 0 1 1 1 1 Brix domain ZapB PF06005.12 KXS10890.1 - 0.00081 19.8 6.1 0.00081 19.8 6.1 8.8 5 4 3 8 8 8 2 Cell division protein ZapB RRS1 PF04939.12 KXS10891.1 - 8.4e-57 191.6 0.7 1.5e-56 190.7 0.7 1.4 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) Rho_Binding PF08912.11 KXS10891.1 - 0.0043 17.8 0.4 0.0043 17.8 0.4 2.2 2 0 0 2 2 2 1 Rho Binding O-FucT PF10250.9 KXS10892.1 - 7.9e-15 55.4 0.0 1.9e-14 54.1 0.0 1.6 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Glyco_transf_11 PF01531.16 KXS10892.1 - 0.024 13.8 0.2 0.27 10.4 0.2 2.0 2 0 0 2 2 2 0 Glycosyl transferase family 11 Death PF00531.22 KXS10892.1 - 0.15 12.2 0.0 0.36 11.0 0.0 1.6 1 0 0 1 1 1 0 Death domain PNP_UDP_1 PF01048.20 KXS10895.1 - 5.8e-05 22.5 0.0 0.00012 21.5 0.0 1.4 1 0 0 1 1 1 1 Phosphorylase superfamily DUF647 PF04884.14 KXS10896.1 - 1.4e-78 263.9 1.9 3.2e-78 262.7 1.9 1.5 1 1 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis PI3_PI4_kinase PF00454.27 KXS10897.1 - 4.6e-46 157.7 0.0 9.7e-46 156.6 0.0 1.5 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase SMN PF06003.12 KXS10897.1 - 0.22 10.7 1.3 0.45 9.7 1.3 1.4 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Hist_deacetyl PF00850.19 KXS10898.1 - 4.1e-82 276.1 0.0 5.4e-82 275.7 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain eIF-3c_N PF05470.12 KXS10898.1 - 0.75 8.0 3.3 1.2 7.4 3.3 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PIG-S PF10510.9 KXS10899.1 - 2.9e-122 409.1 0.4 3.4e-122 408.9 0.4 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein Vma12 PF11712.8 KXS10899.1 - 0.03 14.4 0.1 0.069 13.2 0.1 1.5 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase MCD PF05292.11 KXS10899.1 - 0.042 13.4 0.1 0.069 12.7 0.1 1.3 1 0 0 1 1 1 0 Malonyl-CoA decarboxylase C-terminal domain zf-Nse PF11789.8 KXS10900.1 - 5.3e-17 61.4 1.3 1.2e-16 60.3 1.3 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 KXS10900.1 - 1.3e-07 31.5 0.5 2.4e-07 30.7 0.5 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KXS10900.1 - 0.00032 20.5 0.2 0.00064 19.5 0.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KXS10900.1 - 0.0047 17.1 0.9 0.0084 16.2 0.9 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-MIZ PF02891.20 KXS10900.1 - 0.0069 16.1 0.5 0.015 15.1 0.5 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-C3HC4 PF00097.25 KXS10900.1 - 0.0092 15.8 0.6 0.018 14.9 0.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Mss51 PF13824.6 KXS10900.1 - 0.012 15.7 0.2 0.034 14.2 0.2 1.8 1 1 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 Rtf2 PF04641.12 KXS10900.1 - 0.015 14.7 0.5 0.036 13.4 0.0 1.7 1 1 1 2 2 2 0 Rtf2 RING-finger zf-RING_2 PF13639.6 KXS10900.1 - 0.039 14.3 0.6 0.066 13.6 0.6 1.4 1 0 0 1 1 1 0 Ring finger domain Enkurin PF13864.6 KXS10901.1 - 3.9e-20 72.1 2.4 3.9e-20 72.1 2.4 2.2 2 0 0 2 2 2 1 Calmodulin-binding Flg_hook PF02120.16 KXS10901.1 - 0.035 14.0 0.2 0.085 12.8 0.2 1.6 1 0 0 1 1 1 0 Flagellar hook-length control protein FliK Ras PF00071.22 KXS10902.1 - 2.2e-19 69.6 0.0 2.4e-19 69.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXS10902.1 - 1.1e-15 57.8 0.0 1.2e-15 57.7 0.0 1.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KXS10902.1 - 0.014 15.5 0.0 0.016 15.3 0.0 1.0 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_5 PF07728.14 KXS10902.1 - 0.017 15.1 0.0 0.02 14.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Arf PF00025.21 KXS10902.1 - 0.019 14.4 0.0 0.023 14.2 0.0 1.0 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA_24 PF13479.6 KXS10902.1 - 0.069 12.9 0.1 0.069 12.9 0.1 1.4 1 1 0 1 1 1 0 AAA domain GCP_C_terminal PF04130.13 KXS10903.1 - 2e-69 234.5 1.4 3e-69 233.9 1.4 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 KXS10903.1 - 1.7e-63 215.1 0.0 4.9e-63 213.6 0.0 1.7 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal UPF0184 PF03670.13 KXS10904.1 - 0.00026 21.3 1.4 0.00031 21.1 0.8 1.5 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0184) CCDC53 PF10152.9 KXS10904.1 - 0.0049 17.3 4.2 0.0055 17.1 4.2 1.0 1 0 0 1 1 1 1 Subunit CCDC53 of WASH complex TolA_bind_tri PF16331.5 KXS10904.1 - 0.048 13.7 0.7 0.071 13.2 0.7 1.2 1 0 0 1 1 1 0 TolA binding protein trimerisation DUF3292 PF11696.8 KXS10904.1 - 0.065 11.6 1.8 0.071 11.5 1.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) EF1_GNE PF00736.19 KXS10905.1 - 5.7e-32 109.8 0.8 5.7e-32 109.8 0.8 2.1 2 0 0 2 2 2 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 KXS10905.1 - 1.5e-10 41.3 6.7 1.5e-10 41.3 6.7 2.7 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_3 PF14497.6 KXS10905.1 - 0.035 14.3 0.1 0.1 12.8 0.0 1.9 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Stm1_N PF09598.10 KXS10905.1 - 0.12 13.2 5.4 0.76 10.7 0.4 2.7 3 0 0 3 3 3 0 Stm1 tRNA-synt_1 PF00133.22 KXS10906.1 - 5.4e-213 708.6 0.0 1e-211 704.3 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KXS10906.1 - 9.2e-38 129.6 0.1 2.2e-37 128.4 0.1 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KXS10906.1 - 1.7e-16 59.9 0.4 4.6e-07 28.9 0.0 4.6 3 2 1 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 KXS10906.1 - 1.3e-09 37.9 7.8 3.1e-09 36.6 0.0 3.3 2 1 2 4 4 4 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 KXS10906.1 - 0.01 15.2 0.0 0.12 11.7 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain DUF1917 PF08939.10 KXS10906.1 - 0.16 11.8 1.5 0.38 10.6 1.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1917) HLH PF00010.26 KXS10907.1 - 1.5e-09 37.6 0.4 2.5e-09 36.9 0.4 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Reprolysin_2 PF13574.6 KXS10907.1 - 0.11 12.3 2.1 0.33 10.8 1.4 1.8 1 1 1 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like PXA PF02194.15 KXS10908.1 - 3.3e-25 89.1 0.0 1.8e-24 86.8 0.0 2.2 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.12 KXS10908.1 - 3.8e-20 72.5 0.1 1.1e-19 71.1 0.1 1.9 1 0 0 1 1 1 1 Sorting nexin C terminal PX PF00787.24 KXS10908.1 - 3e-11 43.3 0.0 3e-10 40.1 0.0 2.4 2 0 0 2 2 2 1 PX domain Mod_r PF07200.13 KXS10909.1 - 6.8e-30 104.1 11.8 6.8e-30 104.1 11.8 1.5 2 0 0 2 2 2 1 Modifier of rudimentary (Mod(r)) protein DUF5320 PF17253.2 KXS10909.1 - 0.00094 20.2 0.8 0.00094 20.2 0.8 2.7 2 1 1 3 3 3 1 Family of unknown function (DUF5320) UQ_con PF00179.26 KXS10909.1 - 0.0032 17.1 0.1 0.0032 17.1 0.1 1.8 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme SKA1 PF07160.12 KXS10909.1 - 0.029 14.2 2.0 0.058 13.2 2.0 1.5 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 Herpes_Helicase PF02689.14 KXS10909.1 - 0.1 10.5 1.0 0.14 10.1 1.0 1.1 1 0 0 1 1 1 0 Helicase PRP3 PF08572.10 KXS10910.1 - 3.5e-76 255.8 0.7 5.4e-76 255.2 0.7 1.3 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 KXS10910.1 - 1.5e-41 141.9 1.9 3.1e-41 140.9 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) DUF4611 PF15387.6 KXS10910.1 - 0.03 14.5 1.6 0.036 14.3 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) DUF4407 PF14362.6 KXS10910.1 - 0.19 11.1 1.7 1.6 8.0 1.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Vpu PF00558.19 KXS10910.1 - 1.2 9.0 0.0 1.2 9.0 0.0 2.9 4 0 0 4 4 4 0 Vpu protein Fib_alpha PF08702.10 KXS10910.1 - 10 6.3 8.1 1.8 8.8 4.2 1.7 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family WD40 PF00400.32 KXS10911.1 - 2.3e-20 72.5 15.7 0.00046 20.9 0.1 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat AMPK1_CBM PF16561.5 KXS10913.1 - 3.5e-07 30.3 0.0 6e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase SH3_9 PF14604.6 KXS10915.1 - 1.5e-06 28.0 0.1 2.7e-06 27.1 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXS10915.1 - 0.0013 18.3 0.1 0.0024 17.4 0.1 1.4 1 0 0 1 1 1 1 SH3 domain Ank_3 PF13606.6 KXS10915.1 - 0.034 14.7 0.0 1.7 9.5 0.0 3.0 3 0 0 3 3 3 0 Ankyrin repeat Ank_2 PF12796.7 KXS10915.1 - 0.12 13.0 0.0 0.48 11.1 0.0 2.0 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) IIGP PF05049.13 KXS10916.1 - 9.7e-18 64.4 0.4 1.7e-17 63.5 0.0 1.6 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) MMR_HSR1 PF01926.23 KXS10916.1 - 7.7e-09 35.6 0.0 2.4e-08 34.1 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KXS10916.1 - 6.8e-05 22.8 0.0 0.00018 21.5 0.0 1.7 1 0 0 1 1 1 1 RsgA GTPase ABC_tran PF00005.27 KXS10916.1 - 0.0013 19.2 0.0 0.003 18.1 0.0 1.9 1 1 0 1 1 1 1 ABC transporter DUF1484 PF07363.11 KXS10916.1 - 0.0024 18.9 1.6 0.0054 17.7 1.3 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1484) FeoB_N PF02421.18 KXS10916.1 - 0.0098 15.4 0.0 0.021 14.4 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B Roc PF08477.13 KXS10916.1 - 0.034 14.4 0.0 0.096 12.9 0.0 1.8 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 KXS10916.1 - 0.036 14.4 0.0 0.099 12.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KXS10916.1 - 0.05 13.3 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 KXS10916.1 - 0.053 14.0 0.6 0.25 11.8 0.6 2.2 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KXS10916.1 - 0.058 14.0 0.2 0.19 12.3 0.1 2.1 1 1 1 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 KXS10916.1 - 0.058 12.7 0.1 0.19 11.0 0.0 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_16 PF13191.6 KXS10916.1 - 0.081 13.3 0.0 0.2 12.0 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain Dynamin_N PF00350.23 KXS10916.1 - 0.098 12.7 1.0 0.49 10.4 0.2 2.5 2 1 1 3 3 3 0 Dynamin family AAA_7 PF12775.7 KXS10916.1 - 0.11 11.9 0.2 0.79 9.2 0.1 2.3 2 1 1 3 3 3 0 P-loop containing dynein motor region ATP-synt_C PF00137.21 KXS10921.1 - 1e-25 89.8 27.9 7.2e-15 55.1 12.9 2.1 2 0 0 2 2 2 2 ATP synthase subunit C SLATT_5 PF18160.1 KXS10921.1 - 0.35 10.2 1.1 0.45 9.8 0.1 1.6 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 Pkinase_Tyr PF07714.17 KXS10922.1 - 4.1e-41 141.0 0.0 5.5e-41 140.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXS10922.1 - 2e-33 115.9 0.0 2.6e-33 115.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Sel1 PF08238.12 KXS10922.1 - 1.2e-11 44.8 8.6 1.7e-06 28.5 0.0 4.8 5 0 0 5 5 5 2 Sel1 repeat APH PF01636.23 KXS10922.1 - 8.4e-05 22.6 0.0 0.00016 21.7 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KXS10922.1 - 0.00043 19.7 0.0 0.00067 19.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KXS10922.1 - 0.036 13.4 0.0 0.064 12.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TMPIT PF07851.13 KXS10923.1 - 2.2e-67 227.6 23.2 4.7e-65 220.0 14.0 2.8 2 1 0 2 2 2 2 TMPIT-like protein SHE3 PF17078.5 KXS10923.1 - 0.04 13.6 0.2 0.063 13.0 0.2 1.2 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 DUF5358 PF17311.2 KXS10923.1 - 0.11 12.4 0.5 0.25 11.3 0.5 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5358) RICH PF05062.12 KXS10923.1 - 0.84 10.0 6.5 4.8 7.6 4.6 2.2 2 0 0 2 2 2 0 RICH domain Arteri_Gl PF00951.18 KXS10924.1 - 1.3 8.8 9.0 2.4 8.0 9.0 1.3 1 0 0 1 1 1 0 Arterivirus GL envelope glycoprotein SnoaL_2 PF12680.7 KXS10925.1 - 0.11 13.1 0.0 0.2 12.3 0.0 1.4 1 0 0 1 1 1 0 SnoaL-like domain LRR_4 PF12799.7 KXS10926.1 - 0.031 14.7 1.8 0.067 13.6 1.8 1.6 1 0 0 1 1 1 0 Leucine Rich repeats (2 copies) DUF4690 PF15756.5 KXS10926.1 - 1.3 9.6 9.5 1.3 9.7 6.7 2.5 2 1 0 2 2 2 0 Small Novel Rich in Cartilage Ank_2 PF12796.7 KXS10927.1 - 4.6e-24 84.8 0.1 6.5e-11 42.7 0.0 3.8 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXS10927.1 - 3.3e-18 65.8 1.6 0.00096 19.7 0.0 4.9 3 1 2 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXS10927.1 - 9e-17 60.9 3.7 0.001 19.3 0.1 6.1 4 2 2 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXS10927.1 - 1.5e-16 58.8 4.8 0.0045 17.4 0.0 7.0 7 0 0 7 7 7 4 Ankyrin repeat Ank PF00023.30 KXS10927.1 - 3.6e-12 46.1 5.0 0.085 13.3 0.0 7.8 8 0 0 8 8 8 3 Ankyrin repeat Phage_holin_7_1 PF16081.5 KXS10928.1 - 0.015 15.5 0.8 0.027 14.7 0.8 1.3 1 0 0 1 1 1 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family Statherin PF03875.13 KXS10931.1 - 0.16 12.1 0.0 0.32 11.1 0.0 1.5 1 0 0 1 1 1 0 Statherin Ribosomal_S8e PF01201.22 KXS10933.1 - 7.1e-43 146.1 6.2 1.5e-42 145.0 6.2 1.6 1 1 0 1 1 1 1 Ribosomal protein S8e DUF3523 PF12037.8 KXS10933.1 - 0.56 9.5 13.3 0.81 9.0 13.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3523) DUF429 PF04250.13 KXS10933.1 - 1.3 8.7 6.0 1.3 8.8 4.7 1.7 2 1 0 2 2 2 0 Protein of unknown function (DUF429) Aldo_ket_red PF00248.21 KXS10934.1 - 1.3e-42 146.0 0.0 1.7e-18 66.8 0.0 3.2 1 1 2 3 3 3 3 Aldo/keto reductase family DUF2139 PF09910.9 KXS10934.1 - 0.0014 17.9 0.0 0.0022 17.3 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2139) Aldo_ket_red PF00248.21 KXS10935.1 - 2e-78 263.6 0.0 2.2e-78 263.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Ank_2 PF12796.7 KXS10936.1 - 7.3e-13 48.9 0.1 6.2e-05 23.5 0.0 2.7 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KXS10936.1 - 1.5e-12 47.3 0.3 0.0044 17.4 0.1 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 KXS10936.1 - 3.7e-12 45.3 0.2 0.0045 17.4 0.0 4.5 5 0 0 5 5 5 2 Ankyrin repeat Ank_4 PF13637.6 KXS10936.1 - 3.6e-11 43.4 0.6 0.0012 19.4 0.0 2.8 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXS10936.1 - 3.9e-07 30.2 1.4 0.071 13.4 0.0 3.7 2 2 2 4 4 4 2 Ankyrin repeats (many copies) BNR_6 PF15899.5 KXS10937.1 - 0.45 10.7 7.5 25 5.3 0.2 3.6 3 0 0 3 3 3 0 BNR-Asp box repeat SH3_9 PF14604.6 KXS10938.1 - 1.2e-06 28.3 0.2 2.2e-06 27.4 0.2 1.5 1 0 0 1 1 1 1 Variant SH3 domain Ank_3 PF13606.6 KXS10938.1 - 1e-05 25.5 0.0 0.13 12.9 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 KXS10938.1 - 0.00016 22.2 0.0 0.00052 20.5 0.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXS10938.1 - 0.00048 20.6 0.0 0.61 10.7 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXS10938.1 - 0.00074 19.8 0.0 0.66 10.4 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) SH3_1 PF00018.28 KXS10938.1 - 0.029 14.0 0.1 0.049 13.2 0.1 1.4 1 0 0 1 1 1 0 SH3 domain Cnn_1N PF07989.11 KXS10938.1 - 0.21 11.8 2.7 1.8 8.8 2.7 2.1 1 1 0 1 1 1 0 Centrosomin N-terminal motif 1 Bap31_Bap29_C PF18035.1 KXS10938.1 - 0.31 11.1 0.3 0.58 10.2 0.3 1.4 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain bZIP_1 PF00170.21 KXS10938.1 - 0.36 10.9 2.4 0.93 9.6 0.3 2.2 1 1 1 2 2 2 0 bZIP transcription factor Shugoshin_N PF07558.11 KXS10938.1 - 0.47 10.4 3.2 11 6.0 0.1 2.3 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region Cep57_CLD_2 PF14197.6 KXS10938.1 - 1.3 9.2 4.9 1.6 8.9 0.2 2.2 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 K_channel_TID PF07941.11 KXS10938.1 - 9.6 6.7 14.3 3.1 8.3 5.5 3.2 3 0 0 3 3 3 0 Potassium channel Kv1.4 tandem inactivation domain TROVE PF05731.11 KXS10941.1 - 1.7e-26 93.3 0.0 4.8e-18 65.4 0.0 3.1 2 1 1 3 3 3 3 TROVE domain VWA_CoxE PF05762.14 KXS10941.1 - 0.037 13.4 0.0 0.11 11.8 0.0 1.7 1 1 0 1 1 1 0 VWA domain containing CoxE-like protein SH3_9 PF14604.6 KXS10942.1 - 1.3e-08 34.6 0.2 3.3e-08 33.3 0.2 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXS10942.1 - 9.8e-07 28.3 0.0 1.6e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KXS10942.1 - 0.00097 18.8 0.1 0.0018 17.9 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain Podoplanin PF05808.11 KXS10942.1 - 0.0064 16.6 0.4 0.0064 16.6 0.4 2.3 2 0 0 2 2 2 1 Podoplanin MtrF PF09472.10 KXS10942.1 - 0.046 13.1 3.2 0.098 12.1 3.2 1.6 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) SH3_1 PF00018.28 KXS10943.1 - 0.0026 17.3 0.9 0.0045 16.6 0.0 1.9 2 0 0 2 2 2 1 SH3 domain Ank_2 PF12796.7 KXS10944.1 - 0.0074 16.9 0.0 0.02 15.5 0.0 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXS10944.1 - 0.012 16.1 0.0 10 7.1 0.0 2.5 2 0 0 2 2 2 0 Ankyrin repeat Pkinase_Tyr PF07714.17 KXS10946.1 - 4.2e-19 68.8 0.0 4.4e-19 68.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXS10946.1 - 1.4e-17 64.0 0.0 1.5e-17 63.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KXS10946.1 - 0.00064 19.1 0.0 0.00064 19.1 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KXS10946.1 - 0.029 13.7 0.0 0.034 13.5 0.0 1.0 1 0 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 KXS10946.1 - 0.041 12.7 0.1 0.045 12.5 0.1 1.0 1 0 0 1 1 1 0 Fungal protein kinase Dimer_Tnp_hAT PF05699.14 KXS10947.1 - 4.4e-19 68.1 0.0 5.1e-19 67.9 0.0 1.1 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region GFA PF04828.14 KXS10948.1 - 9.2e-07 29.1 0.8 1.6e-06 28.4 0.8 1.5 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme 7tm_3 PF00003.22 KXS10949.1 - 8.8e-31 107.5 21.1 1.6e-30 106.6 21.1 1.3 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR SBP_bac_1 PF01547.25 KXS10949.1 - 0.028 14.4 0.5 0.053 13.5 0.5 1.4 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein F-box PF00646.33 KXS10949.1 - 0.091 12.7 0.6 0.31 11.0 0.6 1.9 1 0 0 1 1 1 0 F-box domain DUF2749 PF10907.8 KXS10949.1 - 0.24 11.6 1.0 1.1 9.5 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2749) TPR_7 PF13176.6 KXS10950.1 - 5.2e-06 26.1 0.1 1.1e-05 25.1 0.1 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_10 PF13374.6 KXS10950.1 - 0.00028 20.7 1.8 0.00033 20.4 0.3 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 KXS10950.1 - 0.00048 19.8 0.5 0.0017 18.1 0.0 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 KXS10950.1 - 0.0015 18.8 1.1 0.0029 17.8 1.1 1.6 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.6 KXS10950.1 - 0.0037 16.9 0.2 0.0061 16.2 0.2 1.3 1 0 0 1 1 1 1 TPR repeat TPR_19 PF14559.6 KXS10950.1 - 0.0043 17.5 0.3 0.008 16.7 0.2 1.5 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 KXS10950.1 - 0.013 16.2 0.1 0.035 14.9 0.0 1.8 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_16 PF13432.6 KXS10950.1 - 0.022 15.4 0.2 0.022 15.4 0.2 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Vps39_1 PF10366.9 KXS10950.1 - 0.028 14.7 0.2 0.034 14.4 0.2 1.2 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 1 TPR_2 PF07719.17 KXS10950.1 - 0.091 12.9 1.0 0.23 11.7 0.1 2.1 3 0 0 3 3 3 0 Tetratricopeptide repeat PPR PF01535.20 KXS10950.1 - 0.1 12.9 0.1 0.33 11.3 0.0 1.9 2 0 0 2 2 2 0 PPR repeat adh_short PF00106.25 KXS10952.1 - 1.3e-36 125.9 0.1 1.5e-36 125.7 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXS10952.1 - 9.9e-28 97.3 0.0 1.3e-27 96.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXS10952.1 - 3.7e-08 33.5 0.2 5.6e-08 32.9 0.2 1.3 1 0 0 1 1 1 1 KR domain AdoHcyase_NAD PF00670.21 KXS10952.1 - 0.016 15.3 0.2 0.023 14.8 0.2 1.3 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Epimerase PF01370.21 KXS10952.1 - 0.016 14.6 0.1 0.047 13.1 0.1 1.8 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.19 KXS10952.1 - 0.031 13.7 0.1 0.048 13.0 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 KXS10952.1 - 0.1 11.7 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 3HCDH_N PF02737.18 KXS10952.1 - 0.12 12.3 0.2 0.26 11.2 0.1 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SH3_9 PF14604.6 KXS10953.1 - 2.9e-11 43.1 0.1 4.9e-11 42.3 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain Ank_4 PF13637.6 KXS10953.1 - 9.2e-08 32.5 0.0 0.029 15.0 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXS10953.1 - 1.2e-07 31.4 0.7 0.0066 16.9 0.1 4.2 5 0 0 5 5 5 2 Ankyrin repeat Ank_2 PF12796.7 KXS10953.1 - 1.4e-07 32.0 0.0 0.0016 19.0 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 KXS10953.1 - 1.2e-06 28.7 0.3 0.029 14.8 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeat SH3_1 PF00018.28 KXS10953.1 - 7.8e-05 22.2 0.2 0.00015 21.3 0.2 1.5 1 0 0 1 1 1 1 SH3 domain Ank_5 PF13857.6 KXS10953.1 - 9.9e-05 22.6 0.0 0.22 11.9 0.0 3.7 4 0 0 4 4 4 1 Ankyrin repeats (many copies) SH3_2 PF07653.17 KXS10953.1 - 0.01 15.5 0.0 0.046 13.4 0.0 2.0 2 0 0 2 2 2 0 Variant SH3 domain bZIP_2 PF07716.15 KXS10953.1 - 1.5 9.0 5.6 4.3 7.5 0.4 2.4 2 0 0 2 2 2 0 Basic region leucine zipper TolA_bind_tri PF16331.5 KXS10954.1 - 0.0048 17.0 0.9 0.011 15.8 0.9 1.6 1 0 0 1 1 1 1 TolA binding protein trimerisation KLRAQ PF10205.9 KXS10954.1 - 0.017 15.4 1.3 0.028 14.7 0.2 1.8 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein SGP PF17228.2 KXS10954.1 - 7.9 7.4 29.2 4.4 8.2 5.7 2.1 1 1 1 2 2 2 0 Sulphur globule protein SH3_2 PF07653.17 KXS10955.1 - 0.0037 16.9 0.0 0.0054 16.4 0.0 1.2 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KXS10955.1 - 0.034 14.0 0.0 0.049 13.5 0.0 1.2 1 0 0 1 1 1 0 Variant SH3 domain SH3_1 PF00018.28 KXS10955.1 - 0.035 13.7 0.0 0.049 13.2 0.0 1.2 1 0 0 1 1 1 0 SH3 domain SH3_1 PF00018.28 KXS10956.1 - 5.7e-06 25.8 0.1 9.6e-06 25.1 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KXS10956.1 - 0.00023 21.0 0.3 0.002 17.9 0.2 2.2 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 KXS10956.1 - 0.0011 18.6 0.1 0.0019 17.9 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain Stevor PF17410.2 KXS10956.1 - 0.11 12.0 0.1 0.17 11.4 0.1 1.1 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame CcmD PF04995.14 KXS10956.1 - 0.12 12.5 0.9 0.33 11.1 0.9 1.8 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) PTP_tm PF18861.1 KXS10956.1 - 0.21 11.6 0.4 7.5 6.5 0.1 2.1 2 0 0 2 2 2 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J MtrF PF09472.10 KXS10956.1 - 0.54 9.7 2.4 5.6 6.4 4.2 1.8 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) Ank_2 PF12796.7 KXS10957.1 - 2.3e-16 60.2 0.5 6.4e-11 42.7 0.1 3.1 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXS10957.1 - 4.2e-09 36.8 0.4 0.039 14.5 0.0 4.0 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXS10957.1 - 1.3e-08 34.4 2.1 0.97 10.2 0.2 5.4 5 1 1 6 6 6 3 Ankyrin repeat Ank PF00023.30 KXS10957.1 - 2.4e-07 30.9 6.9 0.33 11.5 0.1 5.4 4 1 1 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 KXS10957.1 - 0.00011 22.4 5.5 0.17 12.2 0.2 4.3 3 1 1 4 4 4 2 Ankyrin repeats (many copies) ATG16 PF08614.11 KXS10958.1 - 0.0014 18.9 2.9 0.0022 18.3 2.9 1.3 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Ank_3 PF13606.6 KXS10958.1 - 0.0021 18.4 0.2 0.16 12.6 0.1 3.5 5 0 0 5 5 5 1 Ankyrin repeat Ank_2 PF12796.7 KXS10958.1 - 0.015 15.9 0.0 0.067 13.8 0.0 2.1 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXS10958.1 - 0.02 15.2 0.0 1.2 9.5 0.1 2.8 2 0 0 2 2 2 0 Ankyrin repeats (many copies) SH3_9 PF14604.6 KXS10958.1 - 0.11 12.3 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain YabA PF06156.13 KXS10958.1 - 0.21 12.2 0.2 0.38 11.4 0.2 1.3 1 0 0 1 1 1 0 Initiation control protein YabA DivIC PF04977.15 KXS10958.1 - 2.9 7.7 4.3 5.4 6.9 0.5 1.7 1 1 1 2 2 2 0 Septum formation initiator SH3_1 PF00018.28 KXS10959.1 - 0.0083 15.7 0.1 0.02 14.5 0.1 1.6 1 0 0 1 1 1 1 SH3 domain TSC22 PF01166.18 KXS10959.1 - 0.012 15.9 0.2 0.075 13.3 0.0 2.1 2 0 0 2 2 2 0 TSC-22/dip/bun family Shugoshin_N PF07558.11 KXS10959.1 - 0.024 14.5 0.3 0.27 11.2 0.4 2.2 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region SH3_9 PF14604.6 KXS10959.1 - 0.035 14.0 0.0 0.091 12.6 0.0 1.7 1 0 0 1 1 1 0 Variant SH3 domain GIT_CC PF16559.5 KXS10959.1 - 0.076 12.9 0.3 0.13 12.1 0.3 1.4 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor TPR_MLP1_2 PF07926.12 KXS10959.1 - 0.094 12.8 0.6 0.15 12.2 0.6 1.2 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein bZIP_2 PF07716.15 KXS10959.1 - 0.12 12.5 0.7 0.34 11.0 0.4 1.9 2 0 0 2 2 2 0 Basic region leucine zipper Ank_4 PF13637.6 KXS10959.1 - 0.17 12.5 0.0 17 6.1 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeats (many copies) bZIP_1 PF00170.21 KXS10959.1 - 0.18 11.9 0.2 0.34 11.0 0.2 1.4 1 0 0 1 1 1 0 bZIP transcription factor Antimicrobial19 PF08225.11 KXS10961.1 - 0.26 10.9 1.3 0.4 10.3 0.3 1.9 2 0 0 2 2 2 0 Pseudin antimicrobial peptide Ank_2 PF12796.7 KXS10963.1 - 2.7e-17 63.1 0.0 3.6e-11 43.5 0.0 3.6 1 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXS10963.1 - 5.7e-11 42.7 0.1 0.00074 20.0 0.0 4.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXS10963.1 - 4.4e-10 38.9 3.8 0.043 14.4 0.0 6.5 6 1 1 7 7 7 2 Ankyrin repeat Ank PF00023.30 KXS10963.1 - 2.8e-09 37.0 5.9 0.5 10.9 0.1 5.6 5 1 1 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 KXS10963.1 - 1.1e-06 28.8 0.3 0.03 14.7 0.1 4.2 2 1 2 4 4 4 3 Ankyrin repeats (many copies) 3HCDH_RFF PF18321.1 KXS10963.1 - 0.00061 20.2 0.5 0.0017 18.7 0.5 1.7 1 0 0 1 1 1 1 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain F-box-like_2 PF13013.6 KXS10963.1 - 0.0058 16.6 0.0 0.01 15.8 0.0 1.4 1 0 0 1 1 1 1 F-box-like domain Ank_2 PF12796.7 KXS10964.1 - 6.5e-11 42.7 0.1 3.7e-05 24.2 0.0 2.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXS10964.1 - 4.5e-06 27.1 0.0 0.071 13.7 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXS10964.1 - 4.8e-06 26.7 0.1 0.01 16.1 0.0 2.5 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KXS10964.1 - 7.1e-05 23.1 0.1 0.57 10.7 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 KXS10964.1 - 0.00011 22.3 0.0 0.33 11.7 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeat Maf_N PF08383.11 KXS10964.1 - 0.21 11.4 0.2 3.4 7.5 0.4 2.2 2 0 0 2 2 2 0 Maf N-terminal region Ank_2 PF12796.7 KXS10965.1 - 8.5e-12 45.5 1.3 0.005 17.4 0.1 3.3 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXS10965.1 - 2.1e-10 40.6 1.3 0.00096 19.4 0.2 3.9 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXS10965.1 - 1e-07 31.6 0.8 0.12 13.0 0.0 4.4 5 0 0 5 5 5 2 Ankyrin repeat Ank_4 PF13637.6 KXS10965.1 - 1.6e-06 28.6 3.5 0.0089 16.6 0.0 4.2 3 1 3 6 6 6 3 Ankyrin repeats (many copies) Ank PF00023.30 KXS10965.1 - 0.025 15.0 1.9 2.2 8.9 0.1 3.2 2 1 1 3 3 3 0 Ankyrin repeat F-box-like_2 PF13013.6 KXS10965.1 - 0.13 12.3 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 F-box-like domain FAD_binding_4 PF01565.23 KXS10966.1 - 8.7e-16 57.9 0.4 1.9e-15 56.9 0.2 1.6 2 0 0 2 2 2 1 FAD binding domain Ank_2 PF12796.7 KXS10967.1 - 7e-31 106.7 8.6 3.6e-07 30.7 0.2 5.7 3 2 4 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXS10967.1 - 2.2e-18 66.4 12.6 0.024 15.2 0.1 8.7 7 2 1 9 9 9 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXS10967.1 - 3.6e-16 59.0 7.4 0.17 12.2 0.0 9.1 6 4 3 9 9 9 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXS10967.1 - 6.9e-16 56.8 9.8 0.39 11.4 0.0 12.5 12 1 1 13 13 13 2 Ankyrin repeat Ank PF00023.30 KXS10967.1 - 5.4e-11 42.4 23.6 0.076 13.5 0.0 11.1 9 3 1 10 10 10 2 Ankyrin repeat PELOTA_1 PF15608.6 KXS10967.1 - 0.032 14.1 0.1 0.12 12.3 0.1 1.9 1 0 0 1 1 1 0 PELOTA RNA binding domain DUF1296 PF06972.11 KXS10967.1 - 0.16 12.2 0.0 0.53 10.5 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1296) DSPc PF00782.20 KXS10968.1 - 5.2e-08 32.8 0.0 6.5e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KXS10968.1 - 0.00011 21.8 0.0 0.00016 21.3 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 KXS10968.1 - 0.0023 17.6 1.0 0.0043 16.7 0.0 1.8 2 0 0 2 2 2 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) UCH PF00443.29 KXS10969.1 - 5.8e-35 121.0 0.0 7.1e-35 120.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KXS10969.1 - 7.3e-17 61.9 0.0 5e-11 42.8 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase YjeF_N PF03853.15 KXS10970.1 - 1.6e-10 41.2 0.0 1.8e-10 41.0 0.0 1.0 1 0 0 1 1 1 1 YjeF-related protein N-terminus YjeF_N PF03853.15 KXS10971.1 - 0.11 12.4 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 YjeF-related protein N-terminus Peptidase_S8 PF00082.22 KXS10972.1 - 5e-39 134.3 1.4 1.2e-38 133.1 1.4 1.4 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 KXS10972.1 - 4.6e-14 52.8 0.0 8.7e-14 52.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 Trypan_PARP PF05887.11 KXS10972.1 - 0.0038 17.2 2.5 0.0038 17.2 2.5 1.9 2 0 0 2 2 2 1 Procyclic acidic repetitive protein (PARP) DUF2868 PF11067.8 KXS10972.1 - 0.49 9.9 1.5 0.82 9.1 1.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) TALPID3 PF15324.6 KXS10972.1 - 1.5 6.4 5.3 2.3 5.8 5.3 1.2 1 0 0 1 1 1 0 Hedgehog signalling target Candida_ALS PF05792.13 KXS10972.1 - 3.9 8.1 6.3 8.8 7.0 6.3 1.6 1 0 0 1 1 1 0 Candida agglutinin-like (ALS) NMO PF03060.15 KXS10973.1 - 7.2e-58 196.5 1.1 1.1e-57 195.9 1.1 1.4 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KXS10973.1 - 7.9e-12 44.8 2.1 2.6e-10 39.8 2.1 2.2 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KXS10973.1 - 2.3e-08 33.4 3.7 3.7e-08 32.8 3.7 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 KXS10973.1 - 0.11 11.6 4.7 0.2 10.8 3.9 1.7 2 0 0 2 2 2 0 Conserved region in glutamate synthase Polysacc_deac_1 PF01522.21 KXS10974.1 - 2.2e-23 82.5 0.0 3.7e-23 81.8 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase La PF05383.17 KXS10975.1 - 2.2e-21 75.7 0.1 3.8e-21 74.9 0.1 1.4 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 KXS10975.1 - 0.00027 20.7 0.1 0.18 11.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KXS10975.1 - 0.00036 20.5 0.0 0.0012 18.9 0.0 1.9 1 0 0 1 1 1 1 RNA binding motif PHM7_cyt PF14703.6 KXS10975.1 - 0.0023 18.2 0.1 0.51 10.6 0.0 2.5 1 1 1 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter Nup35_RRM_2 PF14605.6 KXS10975.1 - 0.043 13.8 0.0 2.1 8.4 0.0 2.5 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif FoP_duplication PF13865.6 KXS10975.1 - 7.2 7.2 27.6 27 5.4 27.6 2.0 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Zn_clus PF00172.18 KXS10978.1 - 0.0064 16.6 12.3 0.01 15.9 12.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GHMP_kinases_N PF00288.26 KXS10979.1 - 2.9e-17 62.7 1.0 5.8e-17 61.7 1.0 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KXS10979.1 - 0.00017 21.9 0.0 0.00051 20.4 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases C terminal ABC_tran PF00005.27 KXS10981.1 - 7.4e-28 97.8 0.0 8.4e-18 65.2 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC2_membrane PF01061.24 KXS10981.1 - 5.7e-14 52.0 43.9 2.3e-08 33.7 10.8 4.8 3 2 2 5 5 5 4 ABC-2 type transporter Las1 PF04031.13 KXS10982.1 - 1.4e-13 51.3 0.7 6.7e-11 42.5 0.0 2.6 1 1 1 2 2 2 2 Las1-like IDO PF01231.18 KXS10983.1 - 1.6e-121 406.1 0.0 5.2e-76 256.2 0.0 2.2 2 0 0 2 2 2 2 Indoleamine 2,3-dioxygenase TUSC2 PF15000.6 KXS10984.1 - 0.067 13.5 0.0 0.09 13.1 0.0 1.2 1 0 0 1 1 1 0 Tumour suppressor candidate 2 Romo1 PF10247.9 KXS10985.1 - 5.9e-25 87.4 13.2 7.8e-25 87.0 13.2 1.2 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 TMEM65 PF10507.9 KXS10985.1 - 0.04 13.9 0.1 0.63 10.0 0.0 2.0 2 0 0 2 2 2 0 Transmembrane protein 65 Tmemb_14 PF03647.13 KXS10985.1 - 0.061 14.1 1.1 0.061 14.1 1.1 1.7 1 1 1 2 2 2 0 Transmembrane proteins 14C Tim17 PF02466.19 KXS10985.1 - 1.1 9.7 6.0 1.9 8.9 6.0 1.4 1 1 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family SHQ1 PF04925.15 KXS10988.1 - 2.9e-61 206.1 1.6 4.1e-61 205.6 1.6 1.1 1 0 0 1 1 1 1 SHQ1 protein Cyclin_N PF00134.23 KXS10989.1 - 3e-12 46.4 0.2 4.6e-12 45.8 0.2 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain PhetRS_B1 PF18262.1 KXS10989.1 - 0.0017 18.5 0.3 0.0038 17.4 0.3 1.6 1 0 0 1 1 1 1 Phe-tRNA synthetase beta subunit B1 domain Ras PF00071.22 KXS10990.1 - 1.8e-37 128.5 0.0 2.2e-37 128.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXS10990.1 - 2.5e-23 82.6 0.0 5.6e-23 81.4 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXS10990.1 - 3.9e-07 29.7 0.4 7.4e-06 25.5 0.1 2.0 2 0 0 2 2 2 1 ADP-ribosylation factor family DUF815 PF05673.13 KXS10990.1 - 0.0026 16.9 0.0 0.0084 15.3 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) G-alpha PF00503.20 KXS10990.1 - 0.0046 16.2 0.2 0.81 8.8 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit Pox_A32 PF04665.12 KXS10990.1 - 0.016 14.6 0.0 0.025 14.0 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_7 PF12775.7 KXS10990.1 - 0.037 13.6 0.0 0.057 12.9 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region Gtr1_RagA PF04670.12 KXS10990.1 - 0.039 13.3 0.0 0.063 12.6 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region TsaE PF02367.17 KXS10990.1 - 0.047 13.7 0.0 0.093 12.7 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 KXS10990.1 - 0.057 13.1 0.1 0.076 12.7 0.1 1.2 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KXS10990.1 - 0.13 12.2 0.1 7.6 6.4 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase AAA_33 PF13671.6 KXS10990.1 - 0.14 12.3 0.1 0.24 11.6 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KXS10990.1 - 0.19 12.1 0.0 0.31 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Etmic-2 PF06670.11 KXS10991.1 - 0.08 11.9 0.1 0.39 9.6 0.0 1.7 1 1 0 2 2 2 0 Microneme protein Etmic-2 PhoR PF11808.8 KXS10991.1 - 0.35 11.3 5.1 0.25 11.8 3.4 1.6 2 0 0 2 2 2 0 Phosphate regulon sensor protein PhoR PAXNEB PF05625.11 KXS10992.1 - 9.6e-65 219.1 0.0 1.3e-64 218.7 0.0 1.0 1 0 0 1 1 1 1 PAXNEB protein Gelsolin PF00626.22 KXS10993.1 - 9.8e-18 63.8 1.1 1.1e-07 31.7 0.2 2.6 3 0 0 3 3 3 2 Gelsolin repeat Retrotran_gag_2 PF14223.6 KXS10994.1 - 0.14 11.8 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type L31 PF09784.9 KXS10996.1 - 9.6e-21 74.1 0.2 1.4e-20 73.6 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 KcnmB2_inactiv PF09303.10 KXS10996.1 - 0.1 12.4 0.3 2 8.3 0.0 2.3 2 0 0 2 2 2 0 KCNMB2, ball and chain domain Ribosomal_S18 PF01084.20 KXS10997.1 - 3.7e-18 65.5 0.2 1.1e-17 63.9 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein S18 GDI PF00996.18 KXS10998.1 - 3.3e-46 157.7 0.0 2.5e-37 128.4 0.0 2.0 2 0 0 2 2 2 2 GDP dissociation inhibitor CREPT PF16566.5 KXS10998.1 - 0.025 14.8 0.0 0.04 14.1 0.0 1.3 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour RNA_pol_I_A49 PF06870.12 KXS10999.1 - 6.4e-48 163.5 1.5 3.7e-46 157.7 1.5 2.1 1 1 0 1 1 1 1 A49-like RNA polymerase I associated factor SET PF00856.28 KXS11000.1 - 2.6e-17 63.7 1.1 5.5e-16 59.4 0.0 3.2 3 1 0 3 3 3 1 SET domain AWS PF17907.1 KXS11000.1 - 1.2e-15 57.2 4.2 3.1e-15 55.9 4.2 1.8 1 0 0 1 1 1 1 AWS domain SRI PF08236.11 KXS11000.1 - 2.9e-15 56.2 2.3 2.9e-15 56.2 2.3 2.1 2 0 0 2 2 2 1 SRI (Set2 Rpb1 interacting) domain Med26 PF08711.11 KXS11000.1 - 0.003 17.6 0.2 0.003 17.6 0.2 2.3 3 0 0 3 3 3 1 TFIIS helical bundle-like domain Spo12 PF05032.12 KXS11001.1 - 3.5e-09 36.4 0.2 5.4e-09 35.8 0.2 1.3 1 0 0 1 1 1 1 Spo12 family WD40 PF00400.32 KXS11002.1 - 1.2e-12 48.2 10.7 3e-07 31.0 0.2 6.7 7 0 0 7 7 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXS11002.1 - 4.1e-12 46.2 3.1 0.0012 19.1 0.1 5.2 3 2 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 KXS11002.1 - 1.5e-10 40.7 9.1 0.00031 19.9 1.3 4.7 4 1 2 6 6 6 3 Coatomer WD associated region Clathrin PF00637.20 KXS11002.1 - 0.0001 22.2 0.7 1.9 8.4 0.1 4.0 2 1 2 4 4 4 1 Region in Clathrin and VPS TPR_6 PF13174.6 KXS11002.1 - 0.0091 16.6 5.1 7.7 7.4 0.2 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 KXS11002.1 - 0.017 15.1 4.0 9.7 6.5 0.0 5.2 4 1 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KXS11002.1 - 0.059 13.6 0.2 5 7.4 0.0 3.4 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.20 KXS11002.1 - 0.06 13.6 0.1 13 6.3 0.0 4.3 5 0 0 5 5 5 0 PPR repeat TPR_2 PF07719.17 KXS11002.1 - 0.096 12.9 8.1 40 4.7 1.0 5.5 4 2 2 6 6 6 0 Tetratricopeptide repeat PPR_1 PF12854.7 KXS11002.1 - 0.2 11.4 1.2 1.6 8.5 0.0 2.7 2 0 0 2 2 2 0 PPR repeat TPR_19 PF14559.6 KXS11002.1 - 0.64 10.6 4.9 29 5.3 0.0 4.3 4 1 1 5 5 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 KXS11002.1 - 3 8.9 10.2 31 5.8 0.0 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF2870 PF11069.8 KXS11003.1 - 4.1e-40 136.1 1.7 4.1e-40 136.1 1.7 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2870) ThiJ_like PF17124.5 KXS11004.1 - 6e-56 189.2 0.0 7.2e-56 189.0 0.0 1.1 1 0 0 1 1 1 1 ThiJ/PfpI family-like DJ-1_PfpI PF01965.24 KXS11004.1 - 1.7e-08 34.5 0.0 3.7e-08 33.3 0.0 1.8 1 1 0 1 1 1 1 DJ-1/PfpI family GATase_3 PF07685.14 KXS11004.1 - 0.034 13.7 0.0 0.05 13.2 0.0 1.2 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain SNO PF01174.19 KXS11004.1 - 0.15 11.9 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 SNO glutamine amidotransferase family Ion_trans PF00520.31 KXS11005.1 - 1.8e-127 423.6 73.4 2.5e-39 135.0 21.3 4.2 4 0 0 4 4 4 4 Ion transport protein GPHH PF16905.5 KXS11005.1 - 0.075 12.8 0.0 0.22 11.3 0.0 1.8 1 0 0 1 1 1 0 Voltage-dependent L-type calcium channel, IQ-associated GP41 PF00517.17 KXS11005.1 - 0.73 9.7 4.8 0.16 11.8 0.5 2.2 2 0 0 2 2 2 0 Retroviral envelope protein PKD_channel PF08016.12 KXS11005.1 - 2.1 6.9 51.0 0.015 14.0 2.8 6.5 4 3 2 6 6 6 0 Polycystin cation channel FAT PF02259.23 KXS11006.1 - 3.8e-122 407.8 2.6 3.8e-122 407.8 2.6 1.7 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.27 KXS11006.1 - 5.5e-76 255.7 0.1 9.8e-76 254.9 0.1 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.8 KXS11006.1 - 5.8e-69 231.1 8.0 4e-64 215.4 0.8 4.8 4 1 1 5 5 4 3 Domain of unknown function (DUF3385) FRB_dom PF08771.11 KXS11006.1 - 1.5e-47 160.0 2.7 4.9e-47 158.4 0.7 3.0 2 0 0 2 2 2 1 FKBP12-rapamycin binding domain HEAT_EZ PF13513.6 KXS11006.1 - 3.1e-16 59.5 15.0 0.00042 20.7 0.1 10.9 9 2 1 10 10 8 3 HEAT-like repeat HEAT PF02985.22 KXS11006.1 - 3.5e-15 54.8 14.9 0.024 14.9 0.0 11.6 12 0 0 12 12 10 3 HEAT repeat HEAT_2 PF13646.6 KXS11006.1 - 1.1e-14 54.6 19.5 0.0038 17.6 0.0 9.8 7 2 3 10 10 8 6 HEAT repeats FATC PF02260.20 KXS11006.1 - 5.3e-13 48.5 0.9 1.6e-12 47.0 0.9 2.0 1 0 0 1 1 1 1 FATC domain Vac14_Fab1_bd PF12755.7 KXS11006.1 - 1.6e-09 38.2 0.1 1 10.0 0.0 7.9 6 3 2 8 8 8 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 KXS11006.1 - 7.1e-09 35.9 1.1 0.00044 20.3 0.0 5.7 4 1 2 6 6 6 1 non-SMC mitotic condensation complex subunit 1 Sec7_N PF12783.7 KXS11006.1 - 5.1e-06 26.5 5.5 0.042 13.7 2.3 4.4 5 0 0 5 5 4 2 Guanine nucleotide exchange factor in Golgi transport N-terminal IFRD PF05004.13 KXS11006.1 - 1.7e-05 24.1 2.7 0.082 12.0 0.1 4.9 3 1 1 4 4 4 1 Interferon-related developmental regulator (IFRD) Adaptin_N PF01602.20 KXS11006.1 - 7.5e-05 21.5 9.2 0.00038 19.2 0.7 4.4 4 1 0 4 4 4 1 Adaptin N terminal region TPR_19 PF14559.6 KXS11006.1 - 0.00035 21.0 0.0 1.5 9.4 0.0 3.7 2 0 0 2 2 2 1 Tetratricopeptide repeat ParcG PF10274.9 KXS11006.1 - 0.00043 20.5 11.2 1.2 9.2 0.2 6.7 4 2 3 7 7 7 1 Parkin co-regulated protein UME PF08064.13 KXS11006.1 - 0.00065 19.6 3.1 13 5.8 0.2 6.7 6 2 1 7 7 5 0 UME (NUC010) domain TPR_7 PF13176.6 KXS11006.1 - 0.0028 17.6 0.9 4.1 7.6 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat Ecm29 PF13001.7 KXS11006.1 - 0.0075 15.0 4.0 0.23 10.1 0.4 3.8 3 1 0 3 3 3 1 Proteasome stabiliser TPR_16 PF13432.6 KXS11006.1 - 0.012 16.2 2.6 0.67 10.6 0.0 4.2 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 KXS11006.1 - 0.013 15.2 1.5 4.4 7.3 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Dopey_N PF04118.14 KXS11006.1 - 0.026 13.6 3.6 0.18 10.9 0.9 2.8 2 0 0 2 2 2 0 Dopey, N-terminal TPR_2 PF07719.17 KXS11006.1 - 0.031 14.4 2.5 15 6.0 0.1 4.3 3 0 0 3 3 3 0 Tetratricopeptide repeat VirDNA-topo-I_N PF09266.10 KXS11006.1 - 0.037 14.2 0.5 0.12 12.6 0.1 2.1 2 0 0 2 2 1 0 Viral DNA topoisomerase I, N-terminal ANAPC3 PF12895.7 KXS11006.1 - 0.043 14.1 0.2 1.8 8.9 0.0 3.2 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 KXS11006.1 - 0.19 12.4 0.3 48 4.9 0.0 3.9 3 0 0 3 3 2 0 Tetratricopeptide repeat Cohesin_HEAT PF12765.7 KXS11006.1 - 0.22 11.8 0.9 14 6.1 0.0 4.5 4 0 0 4 4 3 0 HEAT repeat associated with sister chromatid cohesion Mg_trans_NIPA PF05653.14 KXS11007.1 - 6.6e-101 337.3 20.6 7.4e-101 337.1 20.6 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 KXS11007.1 - 5e-07 30.0 9.5 5e-07 30.0 9.5 3.8 3 1 0 3 3 3 1 EamA-like transporter family Acyl_transf_3 PF01757.22 KXS11007.1 - 2.5 7.0 17.6 2e+02 0.8 17.6 2.4 1 1 0 1 1 1 0 Acyltransferase family Mg_trans_NIPA PF05653.14 KXS11008.1 - 1.2e-109 366.0 16.1 1.7e-103 345.8 13.2 2.0 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 KXS11008.1 - 1.5e-05 25.2 8.2 1.5e-05 25.2 8.2 3.3 3 1 0 3 3 3 2 EamA-like transporter family Acyl_transf_3 PF01757.22 KXS11008.1 - 0.22 10.6 20.1 0.035 13.2 12.1 2.2 1 1 1 2 2 2 0 Acyltransferase family Otopetrin PF03189.13 KXS11008.1 - 0.6 8.9 5.5 1.1 8.0 5.4 1.4 1 1 0 1 1 1 0 Otopetrin IFT20 PF14931.6 KXS11011.1 - 0.0011 19.1 4.1 0.0011 19.1 4.1 6.4 3 3 1 5 5 5 2 Intraflagellar transport complex B, subunit 20 CENP-F_leu_zip PF10473.9 KXS11011.1 - 0.008 16.2 11.9 0.008 16.2 11.9 5.7 3 2 2 5 5 5 4 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ISG65-75 PF11727.8 KXS11011.1 - 0.011 15.0 5.5 0.011 15.0 5.5 5.4 2 2 4 6 6 6 0 Invariant surface glycoprotein CEP63 PF17045.5 KXS11011.1 - 1.7 8.5 76.3 0.043 13.7 11.6 3.4 3 0 0 3 3 3 0 Centrosomal protein of 63 kDa AAA PF00004.29 KXS11012.1 - 9e-26 90.9 0.0 2.3e-24 86.3 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KXS11012.1 - 2.2e-07 31.2 0.0 0.059 13.7 0.0 3.5 3 1 0 3 3 3 2 AAA domain AAA_5 PF07728.14 KXS11012.1 - 3.1e-05 24.0 0.3 0.00081 19.4 0.1 2.9 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KXS11012.1 - 8.7e-05 23.0 0.0 0.0014 19.1 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain Mg_chelatase PF01078.21 KXS11012.1 - 0.00045 19.7 0.0 0.00086 18.7 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 KXS11012.1 - 0.00083 19.5 0.0 0.0016 18.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 KXS11012.1 - 0.0035 17.0 0.0 1.6 8.5 0.0 2.3 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_2 PF07724.14 KXS11012.1 - 0.0049 17.0 0.0 0.18 11.9 0.0 2.8 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_24 PF13479.6 KXS11012.1 - 0.011 15.5 0.0 0.026 14.2 0.0 1.5 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 KXS11012.1 - 0.013 14.9 0.0 0.026 13.9 0.0 1.4 1 0 0 1 1 1 0 KaiC IstB_IS21 PF01695.17 KXS11012.1 - 0.023 14.4 0.0 0.17 11.6 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_7 PF12775.7 KXS11012.1 - 0.029 13.9 0.0 0.057 12.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_25 PF13481.6 KXS11012.1 - 0.057 13.0 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KXS11012.1 - 0.074 13.3 0.0 0.42 10.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KXS11012.1 - 0.074 13.5 0.1 0.39 11.1 0.0 2.1 2 1 0 2 2 2 0 RNA helicase AAA_11 PF13086.6 KXS11012.1 - 0.11 12.3 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 KXS11012.1 - 0.11 11.9 0.1 2.7 7.3 0.0 2.8 2 1 1 3 3 3 0 Bacterial TniB protein AAA_30 PF13604.6 KXS11012.1 - 0.12 12.1 0.0 1.3 8.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 KXS11012.1 - 0.12 12.4 0.0 7.8 6.5 0.0 2.5 1 1 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KXS11012.1 - 0.12 12.9 0.0 0.27 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KXS11012.1 - 0.16 12.3 0.0 0.59 10.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.12 KXS11012.1 - 0.16 11.7 0.1 0.74 9.5 0.0 2.0 2 1 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain PPTA PF01239.22 KXS11014.1 - 1.6e-38 129.3 14.7 2.9e-10 39.5 0.2 5.4 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat Phage_tail_APC PF16778.5 KXS11014.1 - 0.074 12.9 0.3 0.22 11.4 0.3 1.8 1 0 0 1 1 1 0 Phage tail assembly chaperone protein Sulfotransfer_3 PF13469.6 KXS11014.1 - 0.18 12.2 1.4 0.43 10.9 0.8 1.9 1 1 0 1 1 1 0 Sulfotransferase family MCM PF00493.23 KXS11015.1 - 2.1e-103 344.3 0.3 3.4e-103 343.5 0.3 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KXS11015.1 - 1.2e-37 128.6 0.0 2.2e-37 127.7 0.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM6_C PF18263.1 KXS11015.1 - 2.2e-27 95.4 1.0 2.2e-27 95.4 1.0 2.1 2 0 0 2 2 2 1 MCM6 C-terminal winged-helix domain MCM_lid PF17855.1 KXS11015.1 - 3.2e-23 81.9 4.8 4.4e-23 81.5 3.2 2.1 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 KXS11015.1 - 1.6e-16 60.8 3.8 3.7e-16 59.6 0.6 2.6 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 KXS11015.1 - 1.7e-07 30.8 0.0 2.7e-06 26.9 0.0 2.4 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KXS11015.1 - 3.5e-05 23.8 0.0 8.7e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KXS11015.1 - 8.2e-05 22.5 0.0 0.00017 21.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KXS11015.1 - 0.0021 17.8 0.0 0.0045 16.7 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain RabGAP-TBC PF00566.18 KXS11016.1 - 1.2e-25 90.5 0.0 1.5e-25 90.1 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_7 PF13499.6 KXS11017.1 - 4.7e-12 46.2 2.9 0.0042 17.5 0.5 4.9 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.6 KXS11017.1 - 2.1e-07 30.3 7.3 0.0095 15.8 0.1 5.7 5 0 0 5 5 5 2 EF-hand domain EF-hand_13 PF17958.1 KXS11017.1 - 1.3e-06 28.1 0.0 5.7e-05 22.8 0.0 3.0 3 0 0 3 3 3 1 EF-hand domain EF-hand_8 PF13833.6 KXS11017.1 - 0.0023 17.7 1.9 1.1 9.2 0.1 4.2 4 0 0 4 4 4 1 EF-hand domain pair EF-hand_1 PF00036.32 KXS11017.1 - 0.065 12.8 17.6 0.1 12.2 0.4 5.3 6 1 0 6 6 6 0 EF hand EF-hand_5 PF13202.6 KXS11017.1 - 4.1 7.1 7.4 15 5.3 0.0 3.6 4 0 0 4 4 4 0 EF hand Sel1 PF08238.12 KXS11018.1 - 2.4e-42 142.4 25.2 6.2e-10 39.4 0.6 7.1 7 0 0 7 7 7 6 Sel1 repeat ADH_zinc_N PF00107.26 KXS11019.1 - 3.5e-20 72.3 0.6 3.5e-20 72.3 0.6 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXS11019.1 - 2.4e-12 48.0 0.0 4.3e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXS11019.1 - 2.6e-10 40.2 0.0 5.5e-10 39.1 0.0 1.6 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain NDUF_B12 PF08122.12 KXS11019.1 - 0.037 14.1 0.1 0.085 12.9 0.1 1.6 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B12 subunit family AlaDh_PNT_C PF01262.21 KXS11019.1 - 0.074 12.3 0.1 0.12 11.6 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain PGF-CTERM PF18204.1 KXS11019.1 - 1 9.5 6.2 3.5 7.7 6.2 2.0 1 0 0 1 1 1 0 PGF-CTERM motif Sec16 PF12932.7 KXS11022.1 - 1.5e-11 44.9 0.1 1.5e-11 44.9 0.1 2.9 2 0 0 2 2 2 1 Vesicle coat trafficking protein Sec16 mid-region zinc_ribbon_2 PF13240.6 KXS11022.1 - 0.0001 21.9 3.1 0.00017 21.2 3.1 1.4 1 0 0 1 1 1 1 zinc-ribbon domain zf-ribbon_3 PF13248.6 KXS11022.1 - 0.00018 20.8 3.0 0.00037 19.8 3.0 1.5 1 0 0 1 1 1 1 zinc-ribbon domain OCRE PF17780.1 KXS11022.1 - 0.00024 21.1 6.0 0.00056 19.9 6.0 1.6 1 0 0 1 1 1 1 OCRE domain DZR PF12773.7 KXS11022.1 - 0.00038 20.4 0.5 0.00083 19.3 0.5 1.4 1 0 0 1 1 1 1 Double zinc ribbon UPF0547 PF10571.9 KXS11022.1 - 0.03 14.4 2.3 0.091 12.9 2.3 1.8 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 zinc_ribbon_15 PF17032.5 KXS11022.1 - 0.088 13.6 0.6 0.15 12.8 0.6 1.3 1 0 0 1 1 1 0 zinc-ribbon family Sec16_C PF12931.7 KXS11023.1 - 2.7e-66 224.3 0.0 9.1e-66 222.5 0.0 1.7 2 0 0 2 2 2 1 Sec23-binding domain of Sec16 Redoxin PF08534.10 KXS11024.1 - 3e-35 121.1 0.1 3.6e-35 120.9 0.1 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 KXS11024.1 - 1.1e-11 44.8 0.0 1.2e-11 44.5 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family FAM177 PF14774.6 KXS11025.1 - 5.1e-11 43.0 0.0 6.8e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 FAM177 family Forkhead PF00250.18 KXS11026.1 - 6.8e-13 48.7 0.1 1.3e-12 47.7 0.1 1.5 1 0 0 1 1 1 1 Forkhead domain SQS_PSY PF00494.19 KXS11027.1 - 2.9e-57 194.2 1.1 2.9e-57 194.2 1.1 1.4 2 0 0 2 2 2 1 Squalene/phytoene synthase Metallophos PF00149.28 KXS11028.1 - 5.2e-09 36.9 0.0 6.2e-08 33.4 0.0 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KXS11028.1 - 2.6e-06 27.7 0.4 7.4e-05 23.0 0.0 2.7 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.6 KXS11028.1 - 1.6e-05 24.4 0.0 0.00044 19.7 0.0 2.5 3 0 0 3 3 3 1 Metallophosphoesterase, calcineurin superfamily LRR_4 PF12799.7 KXS11029.1 - 3.8e-29 100.3 4.5 2.6e-05 24.5 0.6 7.4 3 2 5 9 9 9 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXS11029.1 - 3e-27 94.1 2.8 6.1e-05 22.7 0.8 5.8 5 1 0 5 5 5 5 Leucine rich repeat LRR_9 PF14580.6 KXS11029.1 - 2.3e-10 40.3 2.8 0.21 11.1 0.0 4.9 2 2 2 4 4 4 4 Leucine-rich repeat LRR_1 PF00560.33 KXS11029.1 - 8.3e-09 34.8 5.0 0.92 10.3 0.0 8.5 7 2 1 8 8 8 2 Leucine Rich Repeat LRR_6 PF13516.6 KXS11029.1 - 7.1e-06 25.7 9.8 18 5.7 0.3 8.6 9 0 0 9 9 9 2 Leucine Rich repeat Clat_adaptor_s PF01217.20 KXS11032.1 - 3e-46 156.9 2.3 3.5e-46 156.7 2.3 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Pkinase PF00069.25 KXS11033.1 - 1.6e-14 53.9 0.0 1.6e-14 53.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS11033.1 - 1.1e-11 44.5 0.0 1.1e-11 44.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KXS11033.1 - 0.044 13.1 0.0 0.057 12.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KXS11033.1 - 0.066 12.0 0.0 0.066 12.0 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 KXS11033.1 - 0.18 11.7 0.0 0.24 11.3 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family CRAL_TRIO PF00650.20 KXS11035.1 - 1.7e-08 34.3 0.0 2.3e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain RPAP2_Rtr1 PF04181.13 KXS11036.1 - 2e-15 56.8 0.2 4e-15 55.9 0.2 1.5 1 0 0 1 1 1 1 Rtr1/RPAP2 family CH PF00307.31 KXS11038.1 - 2.8e-48 162.6 0.2 7.8e-25 87.2 0.0 2.6 2 0 0 2 2 2 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.10 KXS11038.1 - 1.6e-12 47.3 0.0 5.1e-12 45.7 0.0 1.9 2 0 0 2 2 2 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.8 KXS11038.1 - 2.7e-09 36.7 0.0 6.6e-07 29.1 0.0 2.5 2 0 0 2 2 2 2 CAMSAP CH domain EF-hand_6 PF13405.6 KXS11038.1 - 0.00091 19.0 0.2 0.0058 16.5 0.1 2.4 2 0 0 2 2 2 1 EF-hand domain Spectrin PF00435.21 KXS11038.1 - 0.0013 19.2 0.0 1.5 9.4 0.0 2.7 2 0 0 2 2 2 2 Spectrin repeat EF-hand_1 PF00036.32 KXS11038.1 - 0.0014 18.1 0.0 0.0036 16.8 0.0 1.8 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 KXS11038.1 - 0.0019 18.6 0.1 0.014 15.8 0.1 2.4 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 KXS11038.1 - 0.076 12.9 0.0 7 6.6 0.0 2.8 2 0 0 2 2 2 0 EF-hand domain pair Citrate_synt PF00285.21 KXS11039.1 - 2.1e-106 356.0 0.0 2.5e-106 355.8 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Pkinase PF00069.25 KXS11041.1 - 2e-60 204.4 0.0 2.5e-52 177.9 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXS11041.1 - 3.5e-36 124.8 0.0 7.9e-33 113.8 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KXS11041.1 - 3.3e-07 29.9 0.0 1.2e-06 28.0 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KXS11041.1 - 0.0062 16.5 0.2 0.027 14.4 0.2 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXS11041.1 - 0.036 12.9 0.0 0.052 12.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 KXS11041.1 - 0.075 12.4 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family LSM_int_assoc PF16605.5 KXS11041.1 - 0.084 13.0 0.5 0.16 12.1 0.5 1.4 1 0 0 1 1 1 0 LSM-interacting associated unstructured PDEase_I PF00233.19 KXS11042.1 - 7.9e-65 218.9 1.2 3.1e-34 118.7 0.0 2.3 2 0 0 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase RasGEF PF00617.19 KXS11043.1 - 1.2e-50 172.2 0.0 2.2e-50 171.3 0.0 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KXS11043.1 - 9e-15 54.8 0.0 2.6e-14 53.3 0.0 1.9 1 0 0 1 1 1 1 RasGEF N-terminal motif MMADHC PF10229.9 KXS11043.1 - 0.073 12.8 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Methylmalonic aciduria and homocystinuria type D protein zf-RING_2 PF13639.6 KXS11044.1 - 2.9e-08 33.9 3.0 4.6e-08 33.3 3.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KXS11044.1 - 1.7e-07 31.0 2.9 2.8e-07 30.3 2.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KXS11044.1 - 3.9e-06 26.8 0.7 6.8e-06 26.1 0.7 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 KXS11044.1 - 5.5e-06 26.6 4.9 1.2e-05 25.5 4.9 1.5 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KXS11044.1 - 4.9e-05 23.2 2.2 9e-05 22.4 2.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 KXS11044.1 - 7.6e-05 22.4 2.2 0.00015 21.4 2.2 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KXS11044.1 - 0.00015 21.5 4.4 0.00035 20.3 4.4 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 KXS11044.1 - 0.00016 21.7 4.7 0.0022 18.1 4.7 2.2 1 1 0 1 1 1 1 FANCL C-terminal domain zf-Di19 PF05605.12 KXS11044.1 - 0.0015 18.8 0.9 0.21 11.9 0.1 2.4 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-C3HC4_3 PF13920.6 KXS11044.1 - 0.008 16.0 2.0 0.015 15.2 2.0 1.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXS11044.1 - 0.0084 16.1 2.6 0.037 14.1 2.8 1.9 1 1 1 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KXS11044.1 - 0.021 14.7 2.6 0.035 13.9 2.6 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 PHD PF00628.29 KXS11044.1 - 0.021 14.7 3.3 0.038 13.9 3.3 1.4 1 0 0 1 1 1 0 PHD-finger Zn_ribbon_17 PF17120.5 KXS11044.1 - 0.041 13.5 2.0 0.084 12.5 2.0 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-ribbon_3 PF13248.6 KXS11044.1 - 0.081 12.4 2.2 1.5 8.3 0.2 2.3 2 0 0 2 2 2 0 zinc-ribbon domain CitMHS PF03600.16 KXS11044.1 - 0.09 12.0 3.4 0.13 11.4 3.4 1.2 1 0 0 1 1 1 0 Citrate transporter zf-C3HC4_4 PF15227.6 KXS11044.1 - 0.14 12.4 1.5 0.3 11.3 1.5 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Sgf11 PF08209.11 KXS11044.1 - 0.15 11.6 1.3 0.21 11.2 0.1 1.8 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) zf-Nse PF11789.8 KXS11044.1 - 0.17 11.7 0.9 0.3 11.0 0.9 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Zf_RING PF16744.5 KXS11044.1 - 0.23 11.6 1.2 0.44 10.7 1.2 1.5 1 0 0 1 1 1 0 KIAA1045 RING finger RINGv PF12906.7 KXS11044.1 - 0.35 11.0 2.9 0.79 9.9 3.0 1.6 1 1 0 1 1 1 0 RING-variant domain zf-C3H2C3 PF17122.5 KXS11044.1 - 1.6 8.8 6.5 8.4 6.5 6.5 2.2 1 1 0 1 1 1 0 Zinc-finger Proteasome PF00227.26 KXS11045.1 - 5.3e-64 215.2 0.1 6.8e-64 214.9 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KXS11045.1 - 3.6e-14 52.1 0.2 8.9e-14 50.9 0.1 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Mito_carr PF00153.27 KXS11046.1 - 1.4e-55 185.2 7.2 2.3e-22 78.7 0.1 4.0 3 1 1 4 4 4 4 Mitochondrial carrier protein Serine_protease PF18405.1 KXS11046.1 - 0.00058 19.1 0.1 0.31 10.2 0.0 2.3 2 0 0 2 2 2 2 Gammaproteobacterial serine protease LRR_8 PF13855.6 KXS11047.1 - 9.5e-52 172.6 74.8 1.8e-10 40.4 5.5 9.5 3 2 8 12 12 12 12 Leucine rich repeat LRR_4 PF12799.7 KXS11047.1 - 2.9e-38 129.2 46.3 6.2e-08 32.8 0.7 10.3 2 1 9 12 12 12 10 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KXS11047.1 - 3.3e-12 45.1 43.9 1.2 10.0 1.1 14.6 14 2 0 14 14 14 6 Leucine Rich Repeat LRR_9 PF14580.6 KXS11047.1 - 4.7e-06 26.2 18.4 0.016 14.7 1.1 5.4 2 1 4 7 7 7 4 Leucine-rich repeat LRR_6 PF13516.6 KXS11047.1 - 3.4e-05 23.6 44.6 0.17 12.0 0.4 12.5 13 0 0 13 13 13 4 Leucine Rich repeat LRR_5 PF13306.6 KXS11047.1 - 0.00017 21.6 0.3 0.014 15.3 0.0 3.1 3 0 0 3 3 3 1 BspA type Leucine rich repeat region (6 copies) RRM_1 PF00076.22 KXS11048.1 - 1.7e-09 37.4 0.0 2.9e-07 30.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Peptidase_M22 PF00814.25 KXS11049.1 - 1.2e-83 281.0 0.1 1.2e-82 277.7 0.1 1.9 1 1 0 1 1 1 1 Glycoprotease family STIMATE PF12400.8 KXS11050.1 - 9e-33 113.5 7.4 9e-33 113.5 7.4 1.6 2 0 0 2 2 2 1 STIMATE family KASH_CCD PF14662.6 KXS11051.1 - 1.1e-05 25.4 5.2 1.7e-05 24.8 5.2 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH GIT_CC PF16559.5 KXS11051.1 - 3.4e-05 23.6 2.8 0.00058 19.7 0.9 2.5 2 0 0 2 2 2 1 GIT coiled-coil Rho guanine nucleotide exchange factor SH3_9 PF14604.6 KXS11051.1 - 0.00012 21.8 0.1 0.00022 21.0 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain Shugoshin_N PF07558.11 KXS11051.1 - 0.00016 21.5 11.0 0.052 13.4 1.3 4.2 3 1 1 4 4 4 2 Shugoshin N-terminal coiled-coil region HALZ PF02183.18 KXS11051.1 - 0.00084 19.5 1.2 0.25 11.6 0.0 3.9 2 1 2 4 4 4 1 Homeobox associated leucine zipper MAD PF05557.13 KXS11051.1 - 0.0016 16.9 3.9 0.0023 16.4 3.9 1.1 1 0 0 1 1 1 1 Mitotic checkpoint protein SlyX PF04102.12 KXS11051.1 - 0.0021 18.7 6.9 0.045 14.4 0.5 3.3 1 1 2 3 3 3 2 SlyX SH3_1 PF00018.28 KXS11051.1 - 0.0088 15.6 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 SH3 domain Atg14 PF10186.9 KXS11051.1 - 0.01 14.9 0.0 0.015 14.4 0.0 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TSC22 PF01166.18 KXS11051.1 - 0.012 15.9 1.9 2.7 8.4 0.2 2.7 1 1 1 2 2 2 0 TSC-22/dip/bun family DUF4407 PF14362.6 KXS11051.1 - 0.015 14.7 0.1 0.022 14.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) bZIP_1 PF00170.21 KXS11051.1 - 0.025 14.7 1.2 0.51 10.5 0.1 2.5 1 1 2 3 3 3 0 bZIP transcription factor YabA PF06156.13 KXS11051.1 - 0.031 14.9 1.8 0.63 10.7 1.3 2.5 1 1 0 1 1 1 0 Initiation control protein YabA Spc7 PF08317.11 KXS11051.1 - 0.05 12.5 3.2 0.029 13.3 0.8 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein Rootletin PF15035.6 KXS11051.1 - 0.053 13.5 5.4 0.092 12.8 5.4 1.3 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Filament PF00038.21 KXS11051.1 - 0.057 13.0 2.9 0.088 12.4 2.9 1.3 1 0 0 1 1 1 0 Intermediate filament protein DivIC PF04977.15 KXS11051.1 - 0.062 13.1 7.7 4.1 7.2 0.1 3.3 1 1 1 3 3 3 0 Septum formation initiator ZapB PF06005.12 KXS11051.1 - 0.089 13.2 6.7 1.2 9.6 0.2 2.9 1 1 2 3 3 3 0 Cell division protein ZapB DUF5094 PF17015.5 KXS11051.1 - 0.091 12.9 1.0 0.13 12.3 1.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5094) DUF3450 PF11932.8 KXS11051.1 - 0.17 11.1 4.2 0.27 10.5 4.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) bZIP_2 PF07716.15 KXS11051.1 - 0.18 11.9 8.6 0.8 9.8 0.3 3.5 2 1 2 4 4 3 0 Basic region leucine zipper K-box PF01486.17 KXS11051.1 - 0.21 11.8 0.8 18 5.6 0.1 2.3 1 1 1 2 2 2 0 K-box region Lzipper-MIP1 PF14389.6 KXS11051.1 - 0.35 11.2 2.2 0.93 9.8 1.9 1.9 1 1 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 Cep57_CLD_2 PF14197.6 KXS11051.1 - 0.46 10.6 7.3 2.1 8.5 4.1 2.7 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 Macoilin PF09726.9 KXS11051.1 - 0.47 8.9 2.7 0.65 8.5 2.7 1.1 1 0 0 1 1 1 0 Macoilin family UPF0242 PF06785.11 KXS11051.1 - 0.47 10.5 1.7 0.73 9.9 1.7 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TPR_MLP1_2 PF07926.12 KXS11051.1 - 0.9 9.6 9.0 2.3 8.3 9.0 1.6 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein TMF_TATA_bd PF12325.8 KXS11051.1 - 1.1 9.5 4.9 0.46 10.7 1.0 2.0 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding BRE1 PF08647.11 KXS11051.1 - 1.7 8.8 4.9 5 7.3 2.7 2.0 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase ADIP PF11559.8 KXS11051.1 - 2.1 8.4 9.1 19 5.3 8.1 2.1 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding NAD_binding_8 PF13450.6 KXS11053.1 - 2.5e-09 37.2 0.0 5.8e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXS11053.1 - 3.4e-05 23.2 0.0 0.0069 15.7 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXS11053.1 - 0.00015 21.5 0.5 0.00033 20.3 0.5 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KXS11053.1 - 0.0058 15.8 0.3 0.012 14.8 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 KXS11053.1 - 0.013 16.0 0.0 0.092 13.3 0.2 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KXS11053.1 - 0.09 12.1 0.2 0.18 11.1 0.2 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KXS11053.1 - 0.11 11.7 0.0 0.33 10.1 0.0 1.8 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KXS11053.1 - 0.14 10.6 0.0 0.97 7.8 0.0 2.0 2 0 0 2 2 2 0 Flavin-binding monooxygenase-like Trp_halogenase PF04820.14 KXS11053.1 - 0.14 11.0 0.4 0.22 10.3 0.4 1.3 1 0 0 1 1 1 0 Tryptophan halogenase GIDA PF01134.22 KXS11053.1 - 0.28 10.2 0.1 0.5 9.4 0.1 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A Stk19 PF10494.9 KXS11054.1 - 5.6e-16 59.0 0.0 1.4e-15 57.7 0.0 1.5 1 1 0 1 1 1 1 Serine-threonine protein kinase 19 IMS PF00817.20 KXS11055.1 - 2.8e-41 141.0 0.1 7.3e-41 139.6 0.1 1.8 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 KXS11055.1 - 1.2e-11 45.3 0.0 3.4e-11 43.9 0.0 1.7 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain BRCT_2 PF16589.5 KXS11055.1 - 4.7e-09 36.5 0.0 8.9e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain UBM PF14377.6 KXS11055.1 - 2.6e-07 29.8 5.5 5.4e-05 22.5 0.4 2.6 2 0 0 2 2 2 2 Ubiquitin binding region PTCB-BRCT PF12738.7 KXS11055.1 - 3.1e-06 27.0 0.4 8.7e-06 25.6 0.4 1.8 1 0 0 1 1 1 1 twin BRCT domain REV1_C PF16727.5 KXS11055.1 - 5.2e-06 26.8 0.0 1.6e-05 25.2 0.0 1.9 1 0 0 1 1 1 1 DNA repair protein REV1 C-terminal domain HHH_5 PF14520.6 KXS11055.1 - 0.00021 21.8 0.1 0.001 19.7 0.1 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix domain IMS_HHH PF11798.8 KXS11055.1 - 0.0003 20.9 0.1 0.0012 19.1 0.0 2.1 2 0 0 2 2 1 1 IMS family HHH motif LIG3_BRCT PF16759.5 KXS11055.1 - 0.00031 21.0 0.1 0.00065 19.9 0.1 1.5 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain BRCT PF00533.26 KXS11055.1 - 0.0093 16.3 0.0 0.025 15.0 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DNA_pol_lambd_f PF10391.9 KXS11055.1 - 0.014 15.2 0.0 0.034 14.0 0.0 1.6 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda RNA_pol_A_CTD PF03118.15 KXS11055.1 - 0.022 14.5 0.0 0.049 13.4 0.0 1.5 1 0 0 1 1 1 0 Bacterial RNA polymerase, alpha chain C terminal domain HK97-gp10_like PF04883.12 KXS11055.1 - 0.078 14.0 0.1 1.1 10.3 0.0 2.9 2 0 0 2 2 2 0 Bacteriophage HK97-gp10, putative tail-component Cdd1 PF11731.8 KXS11055.1 - 0.11 12.8 0.0 0.32 11.3 0.0 1.7 1 0 0 1 1 1 0 Pathogenicity locus TAFII55_N PF04658.13 KXS11056.1 - 4.2e-37 127.3 2.0 8.3e-37 126.4 2.0 1.5 1 0 0 1 1 1 1 TAFII55 protein conserved region GrpE PF01025.19 KXS11056.1 - 0.065 12.9 5.9 0.13 11.9 5.9 1.4 1 0 0 1 1 1 0 GrpE OmpH PF03938.14 KXS11056.1 - 0.6 10.4 5.7 1.7 8.9 5.7 1.7 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) SH3_1 PF00018.28 KXS11058.1 - 0.0076 15.8 0.0 0.025 14.2 0.0 1.8 2 0 0 2 2 2 1 SH3 domain Mucin15 PF15672.5 KXS11058.1 - 0.053 13.0 3.7 0.082 12.4 3.7 1.2 1 0 0 1 1 1 0 Cell-membrane associated Mucin15 SH3_9 PF14604.6 KXS11058.1 - 0.13 12.2 0.0 0.39 10.6 0.0 1.9 2 0 0 2 2 2 0 Variant SH3 domain Rick_17kDa_Anti PF05433.15 KXS11058.1 - 0.3 11.0 8.7 0.15 12.0 5.6 2.0 2 0 0 2 2 2 0 Glycine zipper 2TM domain DUF347 PF03988.12 KXS11058.1 - 0.93 9.7 3.7 2.1 8.6 3.7 1.6 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) SKG6 PF08693.10 KXS11058.1 - 0.97 8.9 6.1 0.08 12.4 0.6 2.1 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Pkinase PF00069.25 KXS11059.1 - 1.1e-17 64.3 0.0 1.7e-17 63.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS11059.1 - 2.8e-05 23.5 0.0 4.2e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KXS11059.1 - 0.032 13.6 0.1 0.066 12.6 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family GalP_UDP_transf PF01087.22 KXS11060.1 - 3.4e-69 233.0 0.1 8.9e-68 228.3 0.2 2.3 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.17 KXS11060.1 - 2e-56 190.3 0.0 3.3e-55 186.3 0.0 2.1 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, C-terminal domain HIT PF01230.23 KXS11060.1 - 0.0024 18.6 0.0 0.089 13.5 0.0 2.4 2 0 0 2 2 2 1 HIT domain DUF4921 PF16268.5 KXS11060.1 - 0.0051 15.7 0.2 2.2 7.0 0.1 2.4 2 1 0 2 2 2 2 Domain of unknown function (DUF4921) HSP70 PF00012.20 KXS11061.1 - 2.7e-79 267.0 5.0 2.7e-79 267.0 5.0 2.8 2 1 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 KXS11061.1 - 0.00027 19.9 0.4 0.089 11.6 0.0 2.3 2 0 0 2 2 2 2 MreB/Mbl protein PLU-1 PF08429.11 KXS11061.1 - 0.048 12.8 1.1 0.21 10.7 0.1 2.1 2 0 0 2 2 2 0 PLU-1-like protein DUF4746 PF15928.5 KXS11061.1 - 0.06 12.8 0.5 0.15 11.5 0.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) BcrAD_BadFG PF01869.20 KXS11061.1 - 0.089 12.3 0.8 0.17 11.4 0.1 1.8 1 1 1 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Malate_synthase PF01274.22 KXS11062.1 - 1.2e-222 739.9 0.0 1.4e-222 739.7 0.0 1.0 1 0 0 1 1 1 1 Malate synthase cobW PF02492.19 KXS11063.1 - 7.5e-41 139.6 0.0 1.1e-40 139.1 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 KXS11063.1 - 0.00016 21.5 0.1 0.00068 19.5 0.1 2.1 1 1 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain AAA_23 PF13476.6 KXS11063.1 - 0.0081 16.7 0.3 0.013 16.0 0.3 1.2 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 KXS11063.1 - 0.013 15.4 0.0 0.14 12.1 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 KXS11063.1 - 0.014 15.8 0.1 0.056 13.8 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_33 PF13671.6 KXS11063.1 - 0.028 14.6 0.3 2 8.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain GTP_EFTU PF00009.27 KXS11063.1 - 0.054 13.0 0.0 9.8 5.7 0.1 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain TsaE PF02367.17 KXS11063.1 - 0.085 12.9 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Motilin_assoc PF04643.12 KXS11063.1 - 0.092 12.6 0.1 0.2 11.5 0.1 1.5 1 0 0 1 1 1 0 Motilin/ghrelin-associated peptide DAGAT PF03982.13 KXS11063.1 - 0.26 10.1 0.0 0.43 9.5 0.0 1.2 1 0 0 1 1 1 0 Diacylglycerol acyltransferase Radical_SAM_C PF16199.5 KXS11064.1 - 4e-32 110.1 0.0 9e-32 108.9 0.0 1.6 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 KXS11064.1 - 1.2e-19 71.3 0.7 2.1e-18 67.3 0.1 2.6 3 0 0 3 3 3 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 KXS11064.1 - 2e-11 44.2 0.1 3.5e-11 43.4 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXS11064.1 - 3.5e-06 27.0 0.0 9.7e-06 25.5 0.1 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXS11064.1 - 0.0011 19.3 0.0 0.0022 18.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXS11064.1 - 0.013 15.5 0.0 0.036 14.0 0.0 1.7 1 0 0 1 1 1 0 FR47-like protein CSD PF00313.22 KXS11065.1 - 7.8e-20 70.5 0.0 1.1e-19 70.0 0.0 1.3 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain WD40 PF00400.32 KXS11066.1 - 3.8e-09 37.0 3.4 0.33 11.9 0.3 5.8 6 0 0 6 6 6 3 WD domain, G-beta repeat Cytochrom_D1 PF02239.16 KXS11066.1 - 8.7e-06 24.5 0.2 5.3e-05 21.9 0.1 2.1 2 0 0 2 2 2 1 Cytochrome D1 heme domain Frtz PF11768.8 KXS11066.1 - 0.041 12.2 0.0 0.15 10.3 0.0 1.7 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz Glyco_hydr_30_2 PF14587.6 KXS11067.1 - 2e-13 50.7 0.3 8.3e-13 48.7 0.1 2.0 2 1 0 2 2 2 1 O-Glycosyl hydrolase family 30 RseC_MucC PF04246.12 KXS11067.1 - 0.064 13.2 0.1 0.17 11.8 0.1 1.7 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC COesterase PF00135.28 KXS11067.1 - 0.16 10.8 0.0 0.23 10.3 0.0 1.2 1 0 0 1 1 1 0 Carboxylesterase family Pkinase PF00069.25 KXS11069.1 - 6.5e-07 29.0 0.0 1.4e-06 27.9 0.0 1.6 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS11069.1 - 0.097 11.9 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Aldo_ket_red PF00248.21 KXS11070.1 - 4.1e-51 173.9 0.0 4.7e-51 173.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family RdRP PF05183.12 KXS11071.1 - 9.7e-74 249.0 0.0 1.3e-73 248.6 0.0 1.0 1 0 0 1 1 1 1 RNA dependent RNA polymerase adh_short PF00106.25 KXS11073.1 - 9.8e-11 41.5 0.3 5.9e-10 38.9 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXS11073.1 - 2.3e-07 30.6 0.1 5.6e-07 29.3 0.0 1.6 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase ATXN-1_C PF12547.8 KXS11073.1 - 0.035 14.4 0.8 0.084 13.2 0.8 1.6 1 0 0 1 1 1 0 Capicua transcriptional repressor modulator Glyoxalase PF00903.25 KXS11074.1 - 0.0086 16.3 0.0 0.015 15.5 0.0 1.4 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Methyltransf_2 PF00891.18 KXS11075.1 - 6.3e-31 107.3 0.0 8.1e-31 107.0 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_25 PF13649.6 KXS11075.1 - 0.0001 22.9 0.0 0.00051 20.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain HTH_15 PF12324.8 KXS11075.1 - 0.016 15.1 0.0 0.064 13.2 0.0 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain of alkylmercury lyase Methyltransf_31 PF13847.6 KXS11075.1 - 0.058 13.2 0.0 0.13 12.1 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain Peptidase_S8 PF00082.22 KXS11076.1 - 5.2e-32 111.3 16.3 9.5e-32 110.4 16.3 1.3 1 1 0 1 1 1 1 Subtilase family Ank_4 PF13637.6 KXS11077.1 - 0.00082 19.9 0.0 0.64 10.7 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXS11077.1 - 0.0082 16.6 0.0 1.9 9.3 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.7 KXS11077.1 - 0.024 15.2 0.0 2.6 8.7 0.0 2.8 2 1 0 2 2 2 0 Ankyrin repeats (3 copies) Ank PF00023.30 KXS11077.1 - 0.049 14.1 0.0 6.7 7.3 0.0 3.0 3 0 0 3 3 3 0 Ankyrin repeat Ank_5 PF13857.6 KXS11077.1 - 0.13 12.7 0.0 1.6 9.2 0.0 2.5 2 0 0 2 2 2 0 Ankyrin repeats (many copies) DUF3481 PF11980.8 KXS11078.1 - 0.0029 17.3 0.1 0.0058 16.3 0.1 1.5 1 0 0 1 1 1 1 C-terminal domain of neuropilin glycoprotein F-box-like PF12937.7 KXS11079.1 - 0.002 18.0 0.0 0.0047 16.8 0.0 1.7 1 0 0 1 1 1 1 F-box-like Pkinase PF00069.25 KXS11081.1 - 7.8e-21 74.6 0.0 9e-21 74.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS11081.1 - 6.7e-20 71.5 0.0 8.2e-20 71.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXS11081.1 - 0.0004 19.3 0.0 0.00046 19.1 0.0 1.0 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KXS11081.1 - 0.02 14.2 0.0 0.022 14.1 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KXS11081.1 - 0.21 11.2 0.0 0.29 10.7 0.0 1.1 1 0 0 1 1 1 0 RIO1 family PROL5-SMR PF15621.6 KXS11082.1 - 0.048 14.2 8.0 0.056 14.0 8.0 1.1 1 0 0 1 1 1 0 Proline-rich submaxillary gland androgen-regulated family CitMHS_2 PF16980.5 KXS11083.1 - 5e-12 45.2 9.5 1.2e-05 24.2 0.4 3.1 1 1 2 3 3 3 3 Putative citrate transport DUF4964 PF16334.5 KXS11083.1 - 0.06 12.9 0.3 0.31 10.6 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4964) AA_permease_2 PF13520.6 KXS11084.1 - 4.7e-37 127.8 26.3 5.5e-37 127.6 26.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXS11084.1 - 3.1e-14 52.5 23.5 4e-14 52.1 23.5 1.1 1 0 0 1 1 1 1 Amino acid permease Sel1 PF08238.12 KXS11085.1 - 2.4e-26 91.6 3.0 3.8e-09 36.9 0.2 3.3 3 0 0 3 3 3 3 Sel1 repeat Recombinase PF07508.13 KXS11085.1 - 0.18 12.2 2.8 0.099 13.1 0.8 1.5 2 0 0 2 2 2 0 Recombinase fn3_3 PF14686.6 KXS11085.1 - 4.7 7.1 10.5 4.7 7.1 0.5 3.1 1 1 2 3 3 3 0 Polysaccharide lyase family 4, domain II ox_reductase_C PF08635.10 KXS11085.1 - 4.9 6.8 7.0 10 5.8 0.1 2.9 1 1 2 3 3 3 0 Putative oxidoreductase C terminal domain Pkinase PF00069.25 KXS11086.1 - 1.5e-08 34.3 0.0 1.5e-08 34.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS11086.1 - 2.6e-05 23.6 0.0 2.6e-05 23.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXS11086.1 - 0.0045 15.8 0.1 0.0046 15.8 0.1 1.0 1 0 0 1 1 1 1 Fungal protein kinase RPAP3_C PF13877.6 KXS11088.1 - 0.0036 17.8 0.0 0.0063 17.0 0.0 1.5 1 0 0 1 1 1 1 Potential Monad-binding region of RPAP3 Ecm33 PF12454.8 KXS11089.1 - 0.2 11.9 0.4 46 4.3 0.0 2.8 3 0 0 3 3 3 0 GPI-anchored cell wall organization protein TRI12 PF06609.13 KXS11093.1 - 0.00023 19.7 3.2 0.00025 19.6 3.2 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Vma12 PF11712.8 KXS11093.1 - 0.11 12.6 3.5 1.3 9.1 0.1 2.1 1 1 1 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase F-box-like PF12937.7 KXS11095.1 - 8.1e-05 22.4 0.2 0.00022 21.1 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXS11095.1 - 0.65 10.0 2.5 0.81 9.6 0.2 2.4 2 0 0 2 2 2 0 F-box domain O-FucT PF10250.9 KXS11098.1 - 1.9e-05 24.6 0.0 2e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Polysacc_deac_1 PF01522.21 KXS11100.1 - 0.0012 18.8 0.0 0.002 18.0 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF1180 PF06679.12 KXS11100.1 - 0.78 10.1 7.7 1.5 9.2 7.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) zf-C2H2_3rep PF18868.1 KXS11101.1 - 0.022 15.4 0.1 0.029 15.1 0.1 1.2 1 0 0 1 1 1 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_12 PF18658.1 KXS11101.1 - 0.033 13.8 1.1 0.033 13.8 1.1 1.7 1 1 1 2 2 2 0 Zinc-finger C2H2-type zf-C2H2 PF00096.26 KXS11101.1 - 0.036 14.5 1.9 0.14 12.7 0.3 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type Rubis-subs-bind PF09273.11 KXS11103.1 - 0.0056 17.4 0.0 0.014 16.1 0.0 1.7 1 1 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.28 KXS11103.1 - 0.011 16.1 0.0 0.23 11.8 0.0 2.4 3 0 0 3 3 3 0 SET domain 2OG-FeII_Oxy PF03171.20 KXS11104.1 - 3.4e-22 78.8 0.0 8.9e-22 77.5 0.0 1.6 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 KXS11104.1 - 1.3e-20 74.3 0.0 2e-20 73.7 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Sel1 PF08238.12 KXS11106.1 - 1.8e-71 234.9 25.9 9.8e-11 42.0 0.0 8.3 8 0 0 8 8 8 8 Sel1 repeat TPR_6 PF13174.6 KXS11106.1 - 0.00018 21.9 0.1 1.2e+02 3.6 0.0 6.0 8 0 0 8 8 8 0 Tetratricopeptide repeat Fib_succ_major PF09603.10 KXS11106.1 - 0.11 13.1 21.4 1.9 9.1 2.2 4.8 1 1 3 4 4 4 0 Fibrobacter succinogenes major domain (Fib_succ_major) GyrI-like PF06445.15 KXS11106.1 - 0.7 10.2 3.2 38 4.6 0.0 3.3 1 1 2 4 4 4 0 GyrI-like small molecule binding domain GH-E PF14410.6 KXS11106.1 - 2.2 8.7 4.6 11 6.6 0.3 3.2 3 0 0 3 3 3 0 HNH/ENDO VII superfamily nuclease with conserved GHE residues Ank_2 PF12796.7 KXS11107.1 - 1.9e-25 89.3 0.2 2.9e-11 43.8 0.0 4.2 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXS11107.1 - 6.5e-22 77.6 0.0 1.6e-05 25.4 0.2 6.3 6 1 1 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXS11107.1 - 9e-17 59.5 0.1 0.00056 20.2 0.0 9.0 10 0 0 10 10 10 3 Ankyrin repeat Ank_5 PF13857.6 KXS11107.1 - 9.5e-13 48.1 0.1 0.031 14.6 0.0 6.3 4 1 2 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 KXS11107.1 - 5.8e-09 36.0 4.5 0.23 12.0 0.0 7.8 7 2 2 9 9 9 2 Ankyrin repeat Myb_DNA-binding PF00249.31 KXS11108.1 - 1.4e-07 31.5 0.3 4.3e-07 30.0 0.3 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.17 KXS11108.1 - 8.8e-07 28.6 4.6 1.6e-06 27.8 4.6 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-bind_6 PF13921.6 KXS11108.1 - 9.8e-05 22.5 0.2 0.00021 21.5 0.2 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Tnp_zf-ribbon_2 PF13842.6 KXS11108.1 - 6.9 7.6 8.1 36 5.3 0.2 2.5 1 1 1 2 2 2 0 DDE_Tnp_1-like zinc-ribbon dCache_1 PF02743.18 KXS11109.1 - 0.0041 17.0 3.2 0.0077 16.0 0.2 2.0 1 1 1 2 2 2 1 Cache domain E1-E2_ATPase PF00122.20 KXS11109.1 - 0.07 12.7 0.4 0.11 12.0 0.4 1.3 1 0 0 1 1 1 0 E1-E2 ATPase PUA_3 PF17785.1 KXS11109.1 - 0.13 12.1 0.0 0.37 10.6 0.0 1.8 1 1 0 1 1 1 0 PUA-like domain OapA_N PF08525.11 KXS11109.1 - 0.14 12.1 0.8 0.27 11.2 0.8 1.5 1 0 0 1 1 1 0 Opacity-associated protein A N-terminal motif adh_short_C2 PF13561.6 KXS11110.1 - 3.1e-10 40.0 0.0 3.1e-10 40.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short_C2 PF13561.6 KXS11111.1 - 2.7e-42 144.9 0.3 5.3e-40 137.4 0.3 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXS11111.1 - 2e-40 138.4 0.1 2.4e-40 138.1 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXS11111.1 - 4e-11 43.2 0.1 8.8e-11 42.0 0.0 1.5 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.6 KXS11112.1 - 6.8e-60 202.5 0.0 8e-60 202.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXS11112.1 - 6.5e-43 146.5 0.0 8.4e-43 146.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXS11112.1 - 6.3e-11 42.5 0.0 9.7e-11 41.9 0.0 1.2 1 0 0 1 1 1 1 KR domain FAD_binding_3 PF01494.19 KXS11113.1 - 0.00036 19.9 0.0 0.00042 19.7 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 KXS11113.1 - 0.0037 16.6 0.0 0.005 16.1 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KXS11113.1 - 0.1 11.9 0.0 0.13 11.6 0.0 1.0 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase DapB_N PF01113.20 KXS11114.1 - 0.0036 17.4 0.0 0.0047 17.1 0.0 1.2 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Nucleic_acid_bd PF13820.6 KXS11114.1 - 0.045 13.6 0.0 0.071 13.0 0.0 1.5 1 1 0 1 1 1 0 Putative nucleic acid-binding region ENTH PF01417.20 KXS11115.1 - 6.2e-37 126.4 0.0 8.1e-37 126.0 0.0 1.1 1 0 0 1 1 1 1 ENTH domain VHS PF00790.19 KXS11115.1 - 0.0044 16.9 0.0 0.0055 16.5 0.0 1.2 1 0 0 1 1 1 1 VHS domain ANAPC10 PF03256.16 KXS11116.1 - 5.9e-12 45.6 0.0 7.4e-12 45.3 0.0 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) AAA PF00004.29 KXS11117.1 - 3e-05 24.5 0.0 5.5e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KXS11117.1 - 0.00016 22.1 0.1 0.00034 21.1 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain Viral_helicase1 PF01443.18 KXS11117.1 - 0.00061 19.6 0.1 0.0017 18.1 0.0 1.9 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_24 PF13479.6 KXS11117.1 - 0.00085 19.1 0.0 0.0014 18.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KXS11117.1 - 0.0041 16.9 0.3 0.013 15.2 0.0 2.0 2 1 0 2 2 2 1 AAA domain TniB PF05621.11 KXS11117.1 - 0.0074 15.7 0.0 1.3 8.4 0.0 2.4 2 0 0 2 2 2 1 Bacterial TniB protein AAA_19 PF13245.6 KXS11117.1 - 0.01 16.2 1.7 0.029 14.7 0.1 2.5 2 1 0 2 2 2 0 AAA domain ATPase PF06745.13 KXS11117.1 - 0.013 14.9 0.1 0.17 11.2 0.0 2.1 2 0 0 2 2 2 0 KaiC NTPase_1 PF03266.15 KXS11117.1 - 0.018 14.9 0.1 0.71 9.8 0.1 2.6 3 0 0 3 3 3 0 NTPase AAA_14 PF13173.6 KXS11117.1 - 0.021 14.8 0.0 0.057 13.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_3 PF07726.11 KXS11117.1 - 0.022 14.6 0.0 0.04 13.8 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 KXS11117.1 - 0.026 14.1 0.1 1.1 8.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 KXS11117.1 - 0.031 14.1 0.1 0.3 10.8 0.0 2.4 1 1 1 2 2 2 0 AAA domain AAA_22 PF13401.6 KXS11117.1 - 0.039 14.2 0.1 0.11 12.7 0.1 1.8 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.22 KXS11117.1 - 0.055 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_5 PF07728.14 KXS11117.1 - 0.058 13.4 0.0 0.21 11.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) TrwB_AAD_bind PF10412.9 KXS11117.1 - 0.063 12.2 0.1 0.15 11.0 0.1 1.5 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_18 PF13238.6 KXS11117.1 - 0.071 13.7 0.0 0.12 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KXS11117.1 - 0.077 13.0 0.0 0.4 10.7 0.0 1.9 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 KXS11117.1 - 0.078 13.5 0.1 0.17 12.4 0.1 1.5 1 1 0 1 1 1 0 ABC transporter RuvB_N PF05496.12 KXS11117.1 - 0.081 12.7 0.1 0.24 11.2 0.0 1.7 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 KXS11117.1 - 0.15 12.5 0.0 0.29 11.6 0.0 1.6 1 1 0 1 1 1 0 RNA helicase HIRA_B PF09453.10 KXS11118.1 - 0.15 11.9 2.1 13 5.8 0.1 3.3 3 0 0 3 3 3 0 HIRA B motif DHFR_2 PF06442.11 KXS11118.1 - 0.19 11.6 0.0 0.41 10.5 0.0 1.5 1 0 0 1 1 1 0 R67 dihydrofolate reductase DUF773 PF05600.12 KXS11121.1 - 0.25 10.0 12.9 3.8 6.1 12.9 2.0 1 1 0 1 1 1 0 CDK5 regulatory subunit-associated protein 3 ACAS_N PF16177.5 KXS11121.1 - 2.6 8.0 13.6 32 4.6 1.2 4.5 1 1 2 3 3 3 0 Acetyl-coenzyme A synthetase N-terminus CBM_1 PF00734.18 KXS11124.1 - 1.5e-11 44.0 12.1 2.5e-11 43.3 12.1 1.3 1 0 0 1 1 1 1 Fungal cellulose binding domain Conotoxin PF02950.17 KXS11124.1 - 0.19 12.7 0.1 0.47 11.5 0.1 1.7 1 0 0 1 1 1 0 Conotoxin EphA2_TM PF14575.6 KXS11124.1 - 0.2 12.5 0.0 0.45 11.4 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain LapA_dom PF06305.11 KXS11124.1 - 0.41 10.5 3.5 0.15 11.9 0.2 1.8 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Glyco_hydro_2_N PF02837.18 KXS11126.1 - 7.1e-06 26.0 0.0 1.9e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.17 KXS11126.1 - 8.5e-05 21.8 0.0 0.00023 20.4 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Mannosidase_ig PF17786.1 KXS11126.1 - 0.0015 19.1 0.0 0.0073 16.9 0.0 2.2 3 0 0 3 3 3 1 Mannosidase Ig/CBM-like domain Ig_mannosidase PF17753.1 KXS11126.1 - 0.0041 16.8 0.0 0.01 15.6 0.0 1.6 1 0 0 1 1 1 1 Ig-fold domain Glyco_hydro_2 PF00703.21 KXS11126.1 - 0.085 13.5 0.0 0.19 12.4 0.0 1.6 1 0 0 1 1 1 0 Glycosyl hydrolases family 2 Tocopherol_cycl PF14249.6 KXS11127.1 - 8.1e-09 35.0 0.3 1e-08 34.7 0.3 1.1 1 0 0 1 1 1 1 Tocopherol cyclase FixP_N PF14715.6 KXS11128.1 - 0.45 10.3 4.7 2.5 7.9 1.0 2.7 2 0 0 2 2 2 0 N-terminal domain of cytochrome oxidase-cbb3, FixP DDE_Tnp_4 PF13359.6 KXS11130.1 - 1.3e-20 73.6 0.0 1.7e-20 73.3 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 KXS11130.1 - 0.023 14.4 0.0 0.032 13.9 0.0 1.2 1 0 0 1 1 1 0 Transposase DDE domain Pkinase PF00069.25 KXS11132.1 - 6.7e-16 58.4 0.0 2.2e-15 56.8 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS11132.1 - 8.3e-11 41.7 0.0 2e-10 40.4 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase AAA PF00004.29 KXS11133.1 - 3.3e-58 195.8 0.0 9.8e-41 139.3 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.11 KXS11133.1 - 1.1e-26 93.1 0.3 3.2e-26 91.6 0.3 1.9 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_lid_3 PF17862.1 KXS11133.1 - 1.3e-13 50.6 0.2 1.7e-07 30.9 0.0 2.6 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 KXS11133.1 - 5.7e-07 30.1 8.8 0.021 15.2 0.1 4.6 2 2 1 3 3 3 2 AAA ATPase domain RuvB_N PF05496.12 KXS11133.1 - 2.9e-06 27.1 0.0 0.0038 17.0 0.0 2.8 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KXS11133.1 - 3.9e-06 26.9 0.1 0.12 12.3 0.0 2.9 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KXS11133.1 - 3e-05 24.3 3.5 0.19 12.0 0.2 4.4 2 2 1 3 3 3 2 AAA domain AAA_17 PF13207.6 KXS11133.1 - 5.5e-05 23.6 0.0 0.3 11.5 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 KXS11133.1 - 0.00013 22.1 1.9 0.063 13.4 0.0 3.4 3 0 0 3 3 3 1 AAA domain ABC_tran PF00005.27 KXS11133.1 - 0.00018 22.0 0.1 0.021 15.3 0.0 2.8 2 0 0 2 2 2 1 ABC transporter AAA_14 PF13173.6 KXS11133.1 - 0.00021 21.3 0.0 0.94 9.5 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_19 PF13245.6 KXS11133.1 - 0.00025 21.4 0.0 0.0062 16.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 KXS11133.1 - 0.00032 20.7 0.1 0.42 10.6 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 KXS11133.1 - 0.0005 20.6 4.6 0.13 12.8 0.0 3.2 3 0 0 3 3 2 2 AAA domain RNA_helicase PF00910.22 KXS11133.1 - 0.00075 19.9 0.0 1.7 9.0 0.0 2.7 2 1 0 2 2 2 2 RNA helicase Viral_helicase1 PF01443.18 KXS11133.1 - 0.0009 19.0 0.1 0.2 11.3 0.0 2.7 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_2 PF07724.14 KXS11133.1 - 0.0009 19.4 0.0 0.039 14.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 KXS11133.1 - 0.0029 17.4 0.1 1.2 8.9 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_25 PF13481.6 KXS11133.1 - 0.0029 17.2 5.4 1.5 8.4 0.1 3.9 2 2 1 3 3 3 1 AAA domain Zeta_toxin PF06414.12 KXS11133.1 - 0.004 16.5 0.8 2 7.6 0.0 3.0 3 0 0 3 3 3 1 Zeta toxin TIP49 PF06068.13 KXS11133.1 - 0.0057 15.9 0.0 0.16 11.2 0.0 2.2 2 0 0 2 2 2 1 TIP49 P-loop domain Sigma54_activat PF00158.26 KXS11133.1 - 0.0071 16.1 0.0 1.5 8.5 0.0 2.7 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_7 PF12775.7 KXS11133.1 - 0.0076 15.8 0.0 0.72 9.3 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region Rad17 PF03215.15 KXS11133.1 - 0.014 15.3 0.0 1 9.3 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain Mg_chelatase PF01078.21 KXS11133.1 - 0.018 14.4 0.3 0.73 9.2 0.0 2.8 3 0 0 3 3 2 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 KXS11133.1 - 0.018 15.3 0.0 8.7 6.6 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.11 KXS11133.1 - 0.022 14.6 0.1 0.97 9.3 0.0 3.0 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 KXS11133.1 - 0.023 13.9 0.1 0.48 9.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_24 PF13479.6 KXS11133.1 - 0.027 14.2 0.0 7.7 6.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain Bac_DnaA PF00308.18 KXS11133.1 - 0.032 14.1 0.0 3.7 7.3 0.0 2.2 2 0 0 2 2 2 0 Bacterial dnaA protein Sigma54_activ_2 PF14532.6 KXS11133.1 - 0.035 14.2 0.1 1.7 8.8 0.1 2.8 2 1 0 2 2 2 0 Sigma-54 interaction domain PEX-2N PF09263.10 KXS11133.1 - 0.11 12.8 0.0 0.46 10.8 0.0 2.0 1 1 0 1 1 1 0 Peroxisome biogenesis factor 1, N-terminal NACHT PF05729.12 KXS11133.1 - 0.12 12.3 4.1 6.9 6.6 0.1 3.6 3 1 0 3 3 3 0 NACHT domain Roc PF08477.13 KXS11133.1 - 0.19 11.9 0.1 0.75 10.0 0.0 2.0 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase DUF2075 PF09848.9 KXS11133.1 - 0.19 10.9 0.6 6.5 5.9 0.0 3.0 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2075) cobW PF02492.19 KXS11133.1 - 0.7 9.5 2.7 18 4.9 0.1 3.1 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain Pro_isomerase PF00160.21 KXS11134.1 - 1.2e-46 158.8 0.2 1.4e-46 158.7 0.2 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD CLU PF13236.6 KXS11135.1 - 5.2e-24 85.3 0.0 6.6e-23 81.7 0.0 2.1 1 1 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 KXS11135.1 - 7.7e-08 32.6 0.3 2.1e-07 31.1 0.3 1.7 1 1 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 PH PF00169.29 KXS11135.1 - 0.0031 18.0 0.0 0.006 17.1 0.0 1.5 1 0 0 1 1 1 1 PH domain TPR_12 PF13424.6 KXS11135.1 - 0.0046 17.2 1.0 0.01 16.1 1.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat SPATA9 PF15824.5 KXS11135.1 - 0.095 12.0 0.1 0.18 11.1 0.1 1.3 1 0 0 1 1 1 0 Spermatogenesis-associated protein 9 ROF PF07073.12 KXS11135.1 - 0.095 12.9 0.0 0.26 11.5 0.0 1.7 1 0 0 1 1 1 0 Modulator of Rho-dependent transcription termination (ROF) FAD_binding_3 PF01494.19 KXS11136.1 - 3.5e-22 79.1 0.0 3.4e-21 75.9 0.0 2.4 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KXS11136.1 - 2e-05 24.0 0.3 7.7e-05 22.1 0.3 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXS11136.1 - 0.00019 21.6 0.1 0.00086 19.5 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KXS11136.1 - 0.00094 18.0 0.2 0.0022 16.8 0.1 1.6 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 KXS11136.1 - 0.0011 18.2 0.2 0.002 17.2 0.2 1.6 1 1 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 KXS11136.1 - 0.006 15.7 0.1 0.011 14.8 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain SE PF08491.10 KXS11136.1 - 0.011 14.7 0.0 0.029 13.4 0.0 1.6 2 0 0 2 2 2 0 Squalene epoxidase Pyr_redox_3 PF13738.6 KXS11136.1 - 0.032 13.5 0.2 0.19 11.0 0.1 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KXS11136.1 - 0.067 12.5 0.1 0.11 11.8 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase DAO PF01266.24 KXS11136.1 - 0.17 11.4 0.2 0.53 9.8 0.0 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KXS11136.1 - 0.21 10.4 0.2 4.6 6.0 0.3 2.0 2 0 0 2 2 2 0 Tryptophan halogenase Chromo PF00385.24 KXS11138.1 - 6e-11 42.1 0.1 1.4e-10 40.9 0.0 1.6 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain ParBc PF02195.18 KXS11139.1 - 0.00031 21.0 0.0 0.00089 19.5 0.0 1.7 1 0 0 1 1 1 1 ParB-like nuclease domain RNA_polI_A34 PF08208.11 KXS11139.1 - 0.0049 17.0 2.7 0.0081 16.3 2.7 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase I subunit RPA34.5 Asn_synthase PF00733.21 KXS11141.1 - 1.1e-05 25.2 0.0 0.0022 17.7 0.0 2.2 2 0 0 2 2 2 2 Asparagine synthase Ank_2 PF12796.7 KXS11142.1 - 1.1e-17 64.3 0.0 8.2e-10 39.1 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXS11142.1 - 4.6e-17 61.8 0.8 1.9e-05 24.8 0.0 5.3 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 KXS11142.1 - 1.1e-14 54.1 1.1 0.00049 20.4 0.0 5.7 6 0 0 6 6 6 3 Ankyrin repeat Ank_4 PF13637.6 KXS11142.1 - 1.4e-13 51.0 0.0 9.5e-09 35.6 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXS11142.1 - 4.4e-13 48.1 0.0 0.0022 18.3 0.0 4.8 4 0 0 4 4 4 3 Ankyrin repeat zf-MYND PF01753.18 KXS11142.1 - 8.9e-11 41.7 8.6 8.9e-11 41.7 8.6 1.8 2 0 0 2 2 2 1 MYND finger zf-C6H2 PF15801.5 KXS11142.1 - 0.00027 21.2 5.7 0.00061 20.0 5.7 1.6 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding PDZ_4 PF17816.1 KXS11142.1 - 0.1 13.0 0.1 0.19 12.1 0.1 1.3 1 0 0 1 1 1 0 PDZ domain ABC_tran PF00005.27 KXS11143.1 - 1.6e-42 145.2 0.0 1.1e-20 74.5 0.0 3.4 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KXS11143.1 - 1.9e-25 90.1 27.2 8.6e-22 78.1 13.9 4.8 3 1 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 KXS11143.1 - 6.2e-11 42.2 0.8 0.00025 20.6 0.0 4.7 6 0 0 6 6 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KXS11143.1 - 8.3e-11 42.6 1.3 9.9e-06 26.0 0.1 2.7 2 1 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KXS11143.1 - 1.8e-07 31.2 0.1 0.019 14.9 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 KXS11143.1 - 1.8e-06 27.6 1.0 0.0089 15.8 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA PF00004.29 KXS11143.1 - 3.7e-05 24.2 0.1 2.4 8.6 0.0 4.2 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KXS11143.1 - 6.3e-05 23.3 0.3 0.069 13.4 0.0 3.7 4 0 0 4 4 4 1 AAA domain AAA_21 PF13304.6 KXS11143.1 - 0.00013 21.9 0.7 0.2 11.4 0.0 3.1 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system DUF87 PF01935.17 KXS11143.1 - 0.0002 21.5 1.8 0.044 13.9 0.2 2.7 3 0 0 3 3 2 1 Helicase HerA, central domain MMR_HSR1 PF01926.23 KXS11143.1 - 0.00028 20.9 0.1 1.4 9.0 0.0 2.9 3 0 0 3 3 2 2 50S ribosome-binding GTPase Zeta_toxin PF06414.12 KXS11143.1 - 0.0003 20.1 0.1 0.61 9.3 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin SbcCD_C PF13558.6 KXS11143.1 - 0.00035 20.8 0.2 1.3 9.3 0.0 3.1 3 0 0 3 3 2 2 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 KXS11143.1 - 0.00053 19.8 1.3 0.72 9.5 0.2 3.0 3 0 0 3 3 3 2 AAA domain AAA_33 PF13671.6 KXS11143.1 - 0.0012 19.0 0.1 0.55 10.4 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_23 PF13476.6 KXS11143.1 - 0.0013 19.3 0.0 0.41 11.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KXS11143.1 - 0.002 18.1 0.0 3.9 7.5 0.0 2.9 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 KXS11143.1 - 0.0035 16.9 0.1 1.1 8.8 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_25 PF13481.6 KXS11143.1 - 0.0068 16.0 0.7 0.57 9.7 0.1 2.7 3 0 0 3 3 3 1 AAA domain MeaB PF03308.16 KXS11143.1 - 0.007 15.4 0.2 0.4 9.6 0.0 2.3 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_24 PF13479.6 KXS11143.1 - 0.0079 15.9 0.0 3.9 7.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 KXS11143.1 - 0.008 15.4 0.0 1.3 8.1 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain DUF815 PF05673.13 KXS11143.1 - 0.0081 15.3 0.0 0.71 9.0 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) ATP-synt_ab PF00006.25 KXS11143.1 - 0.014 15.1 0.0 4.1 7.0 0.0 2.4 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_18 PF13238.6 KXS11143.1 - 0.027 15.0 0.5 4.5 7.8 0.0 2.9 3 0 0 3 3 2 0 AAA domain TsaE PF02367.17 KXS11143.1 - 0.029 14.4 0.2 9.8 6.2 0.0 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activat PF00158.26 KXS11143.1 - 0.13 12.0 0.0 9.4 5.9 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain ATP_bind_1 PF03029.17 KXS11143.1 - 0.15 11.8 0.2 17 5.1 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.22 KXS11143.1 - 0.16 12.4 0.1 20 5.6 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_15 PF13175.6 KXS11143.1 - 0.28 10.9 0.0 5.5 6.6 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_28 PF13521.6 KXS11143.1 - 0.28 11.4 1.0 3.8 7.7 0.1 2.8 2 1 1 3 3 3 0 AAA domain Ank_3 PF13606.6 KXS11144.1 - 0.0035 17.7 0.0 0.11 13.1 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.7 KXS11144.1 - 0.016 15.8 0.0 0.056 14.0 0.0 1.8 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXS11144.1 - 0.046 14.0 0.0 0.19 12.1 0.0 2.1 1 0 0 1 1 1 0 Ankyrin repeats (many copies) AAA PF00004.29 KXS11145.1 - 4.4e-18 66.0 0.0 6.9e-18 65.3 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KXS11145.1 - 0.00048 20.6 0.0 0.00089 19.7 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 KXS11145.1 - 0.00089 19.0 0.0 0.0014 18.4 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KXS11145.1 - 0.0021 18.0 0.0 0.0068 16.4 0.0 1.7 1 1 1 2 2 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 KXS11145.1 - 0.0022 17.6 0.1 0.85 9.2 0.1 2.6 2 0 0 2 2 2 2 AAA domain AAA_11 PF13086.6 KXS11145.1 - 0.0065 16.3 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain Glyco_transf_6 PF03414.13 KXS11145.1 - 0.0093 14.8 0.0 0.016 14.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 6 AAA_3 PF07726.11 KXS11145.1 - 0.013 15.4 0.0 0.024 14.5 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) BCS1_N PF08740.11 KXS11145.1 - 0.026 14.5 0.1 0.044 13.8 0.1 1.3 1 0 0 1 1 1 0 BCS1 N terminal AAA_22 PF13401.6 KXS11145.1 - 0.043 14.1 0.3 0.44 10.8 0.1 2.3 1 1 0 2 2 2 0 AAA domain Gtr1_RagA PF04670.12 KXS11145.1 - 0.048 13.0 0.0 0.36 10.1 0.0 2.0 1 1 1 2 2 2 0 Gtr1/RagA G protein conserved region AAA_30 PF13604.6 KXS11145.1 - 0.067 12.9 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 KXS11145.1 - 0.08 12.1 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_18 PF13238.6 KXS11145.1 - 0.12 12.9 0.0 0.34 11.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain NIF PF03031.18 KXS11146.1 - 5.1e-07 29.6 0.0 7.7e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase MFS_1 PF07690.16 KXS11147.1 - 6e-46 157.0 46.5 6e-46 157.0 46.5 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KXS11147.1 - 6.3e-22 77.7 16.2 8e-22 77.4 16.1 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KXS11147.1 - 2e-09 36.8 7.3 2e-09 36.8 7.3 3.1 1 1 2 3 3 3 1 Sugar (and other) transporter GTP_EFTU PF00009.27 KXS11148.1 - 8.5e-67 224.5 0.3 1.3e-66 223.9 0.3 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 KXS11148.1 - 1e-29 102.8 0.0 5e-29 100.6 0.0 2.2 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 KXS11148.1 - 2.8e-23 81.7 0.0 9.9e-23 80.0 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KXS11148.1 - 8e-14 51.8 0.1 2.9e-13 50.0 0.1 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 KXS11148.1 - 9.1e-12 44.9 0.0 1.9e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 KXS11148.1 - 0.00014 21.9 0.2 0.00028 20.9 0.2 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase MFS_1 PF07690.16 KXS11150.1 - 2.2e-51 174.9 38.8 2.2e-51 174.9 38.8 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KXS11150.1 - 7.1e-20 71.0 16.2 1.1e-19 70.4 16.2 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KXS11150.1 - 5.5e-11 42.0 13.9 5.5e-11 42.0 13.9 2.9 2 1 1 3 3 3 1 Sugar (and other) transporter MFS_1_like PF12832.7 KXS11150.1 - 2.3e-06 26.7 6.9 2.3e-06 26.7 6.9 2.3 2 0 0 2 2 2 1 MFS_1 like family RRM_1 PF00076.22 KXS11151.1 - 4e-10 39.4 0.0 5.6e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.23 KXS11151.1 - 2e-07 30.8 3.8 0.012 15.7 1.3 2.6 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.6 KXS11151.1 - 0.036 13.9 3.2 0.036 13.9 3.2 3.1 4 0 0 4 4 4 0 Zinc knuckle zf-CCHC_3 PF13917.6 KXS11151.1 - 0.057 13.4 2.0 1.1 9.3 0.3 2.3 2 0 0 2 2 2 0 Zinc knuckle F-box-like PF12937.7 KXS11152.1 - 0.0016 18.3 3.4 0.0031 17.3 3.4 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXS11152.1 - 0.0076 16.1 1.1 0.017 15.0 1.1 1.6 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KXS11152.1 - 0.12 12.2 0.4 0.26 11.2 0.4 1.5 1 0 0 1 1 1 0 F-box MFS_1 PF07690.16 KXS11154.1 - 1.1e-49 169.3 44.2 2.4e-49 168.2 44.2 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KXS11154.1 - 7.8e-14 51.0 12.0 7.8e-14 51.0 12.0 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KXS11154.1 - 1.9e-08 33.6 8.7 3.8e-07 29.3 1.0 4.1 2 2 1 4 4 4 2 Sugar (and other) transporter Tcp11 PF05794.13 KXS11155.1 - 2.3e-59 201.7 0.0 2.8e-59 201.4 0.0 1.1 1 0 0 1 1 1 1 T-complex protein 11 Nrf1_activ_bdg PF10492.9 KXS11155.1 - 0.14 12.8 0.4 5.2 7.8 0.0 2.5 2 0 0 2 2 2 0 Nrf1 activator activation site binding domain DUF3546 PF12066.8 KXS11157.1 - 1.2e-21 77.0 0.6 4e-21 75.3 0.6 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3546) ARS2 PF04959.13 KXS11157.1 - 4.7e-17 63.0 13.6 4.7e-17 63.0 13.6 2.9 2 1 0 2 2 2 1 Arsenite-resistance protein 2 RRM_1 PF00076.22 KXS11157.1 - 1.3e-05 25.0 0.0 2.8e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C2H2_2 PF12756.7 KXS11157.1 - 0.037 14.3 0.2 0.087 13.2 0.2 1.6 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zinc_ribbon_4 PF13717.6 KXS11157.1 - 0.046 13.6 0.3 0.083 12.8 0.3 1.4 1 0 0 1 1 1 0 zinc-ribbon domain BRAP2 PF07576.12 KXS11157.1 - 0.37 11.0 0.0 0.37 11.0 0.0 2.0 2 0 0 2 2 2 0 BRCA1-associated protein 2 Creatinase_N_2 PF16189.5 KXS11158.1 - 2.4e-30 105.8 0.0 1.2e-28 100.2 0.0 2.4 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 KXS11158.1 - 1.6e-21 77.0 0.0 2.5e-21 76.3 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Peptidase_M24_C PF16188.5 KXS11158.1 - 4.8e-14 52.2 0.3 1.7e-13 50.4 0.1 2.1 2 0 0 2 2 2 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 KXS11158.1 - 4.9e-08 33.7 0.0 2.7e-07 31.3 0.0 2.1 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain CBP_BcsO PF17037.5 KXS11159.1 - 0.66 10.1 6.4 0.96 9.6 6.4 1.3 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsO Sirohm_synth_M PF14824.6 KXS11160.1 - 2.5e-07 30.0 0.1 4.5e-07 29.2 0.1 1.5 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Sirohm_synth_C PF14823.6 KXS11160.1 - 1.9e-05 24.2 1.4 3.1e-05 23.5 1.4 1.2 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal NAD_binding_7 PF13241.6 KXS11160.1 - 0.0093 16.4 0.9 0.015 15.7 0.3 1.7 2 0 0 2 2 2 1 Putative NAD(P)-binding Saf-Nte_pilin PF09460.10 KXS11160.1 - 0.039 14.0 0.1 0.049 13.6 0.1 1.2 1 0 0 1 1 1 0 Saf-pilin pilus formation protein F-box-like PF12937.7 KXS11161.1 - 1.3e-07 31.4 0.8 5e-07 29.5 0.2 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KXS11161.1 - 0.008 16.0 0.7 0.046 13.6 0.3 2.5 2 0 0 2 2 2 1 F-box domain LRR_4 PF12799.7 KXS11161.1 - 0.032 14.7 5.6 35 5.0 0.2 6.1 6 1 1 7 7 7 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KXS11162.1 - 2.4e-05 24.1 2.1 0.00023 21.0 0.3 3.1 3 0 0 3 3 3 1 F-box-like Fungal_trans PF04082.18 KXS11164.1 - 1.8e-11 43.6 0.0 3e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.18 KXS11165.1 - 0.021 13.9 0.0 0.025 13.6 0.0 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain AA_permease PF00324.21 KXS11167.1 - 9.3e-16 57.5 0.3 1.1e-15 57.2 0.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KXS11167.1 - 7.3e-05 21.8 0.0 7.8e-05 21.7 0.0 1.0 1 0 0 1 1 1 1 Amino acid permease 4HBT_2 PF13279.6 KXS11169.1 - 0.00026 21.5 0.0 0.00036 21.0 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily Methyltransf_21 PF05050.12 KXS11170.1 - 1.2e-06 28.7 0.0 1.9e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase FkbM domain zf-CCHC PF00098.23 KXS11171.1 - 2.1e-06 27.6 26.9 0.0069 16.4 0.3 4.4 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_2 PF13696.6 KXS11171.1 - 0.0093 15.8 26.8 0.15 11.9 0.3 4.5 4 0 0 4 4 4 3 Zinc knuckle zf-CCHC_4 PF14392.6 KXS11171.1 - 0.018 14.8 24.1 0.51 10.1 0.5 4.3 4 0 0 4 4 4 0 Zinc knuckle RR_TM4-6 PF06459.12 KXS11171.1 - 3.1 7.5 8.6 4.5 7.0 8.6 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Ribosomal_60s PF00428.19 KXS11172.1 - 8.6e-21 74.3 19.3 8.6e-21 74.3 19.3 1.6 2 1 0 2 2 2 1 60s Acidic ribosomal protein Tic110 PF16940.5 KXS11172.1 - 2.4 6.5 5.7 2.7 6.4 5.7 1.1 1 0 0 1 1 1 0 Chloroplast envelope transporter Spherulin4 PF12138.8 KXS11174.1 - 2.3e-11 43.8 0.0 3.5e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 Spherulation-specific family 4 Csm1 PF12539.8 KXS11175.1 - 2.3e-10 41.0 0.0 2.7e-09 37.5 0.0 2.0 1 1 0 1 1 1 1 Chromosome segregation protein Csm1/Pcs1 PDDEXK_10 PF07788.11 KXS11175.1 - 0.11 12.4 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 PD-(D/E)XK nuclease superfamily Methyltransf_16 PF10294.9 KXS11176.1 - 2.8e-31 108.6 0.1 1.2e-17 64.2 0.0 3.4 3 1 0 3 3 3 2 Lysine methyltransferase PrmA PF06325.13 KXS11176.1 - 1.4e-06 27.9 0.1 2.1e-06 27.4 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KXS11176.1 - 2.6e-05 23.9 0.0 3.9e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 KXS11176.1 - 0.00048 20.8 0.5 0.0014 19.3 0.5 1.8 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXS11176.1 - 0.014 15.3 0.0 0.018 14.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.15 KXS11176.1 - 0.05 13.2 0.0 0.077 12.6 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_31 PF13847.6 KXS11176.1 - 0.057 13.2 0.1 0.089 12.6 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 KXS11176.1 - 0.22 11.3 0.1 0.28 10.9 0.1 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) BRCT_2 PF16589.5 KXS11177.1 - 0.00014 22.2 0.0 0.00024 21.5 0.0 1.3 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain PGA2 PF07543.12 KXS11177.1 - 0.25 11.3 2.8 0.41 10.6 2.8 1.2 1 0 0 1 1 1 0 Protein trafficking PGA2 MccV PF17508.2 KXS11177.1 - 0.36 11.4 0.0 0.36 11.4 0.0 2.1 1 1 1 2 2 2 0 Microcin V bacteriocin SH3_9 PF14604.6 KXS11178.1 - 7e-06 25.8 0.2 3.6e-05 23.5 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain HSBP1 PF06825.12 KXS11178.1 - 0.00099 18.9 2.3 0.049 13.5 0.3 2.4 1 1 1 2 2 2 2 Heat shock factor binding protein 1 CLZ PF16526.5 KXS11178.1 - 0.0025 18.1 1.1 0.0025 18.1 1.1 2.4 1 1 1 2 2 2 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Ank_3 PF13606.6 KXS11178.1 - 0.0034 17.7 0.1 6.2 7.7 0.0 3.0 2 0 0 2 2 2 1 Ankyrin repeat Dynamitin PF04912.14 KXS11178.1 - 0.014 14.7 1.3 0.02 14.2 1.3 1.2 1 0 0 1 1 1 0 Dynamitin SH3_1 PF00018.28 KXS11178.1 - 0.015 14.9 0.0 0.031 13.9 0.0 1.5 1 0 0 1 1 1 0 SH3 domain ABC_tran_CTD PF16326.5 KXS11178.1 - 0.019 15.2 5.8 0.03 14.6 2.0 2.3 1 1 1 2 2 2 0 ABC transporter C-terminal domain DUF4515 PF14988.6 KXS11178.1 - 0.069 13.0 5.8 0.12 12.2 5.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4515) Atg14 PF10186.9 KXS11178.1 - 0.088 11.9 1.4 0.12 11.4 1.4 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF3584 PF12128.8 KXS11178.1 - 0.12 9.9 4.0 0.15 9.5 4.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Baculo_PEP_C PF04513.12 KXS11178.1 - 0.13 12.4 6.6 0.031 14.3 3.2 1.6 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus PspA_IM30 PF04012.12 KXS11178.1 - 0.18 11.3 5.7 0.39 10.3 5.7 1.5 1 0 0 1 1 1 0 PspA/IM30 family DASH_Hsk3 PF08227.11 KXS11178.1 - 0.2 12.0 5.7 0.58 10.6 1.6 2.7 1 1 1 2 2 2 0 DASH complex subunit Hsk3 like OmpH PF03938.14 KXS11178.1 - 0.23 11.8 4.3 0.39 11.0 4.3 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) BLOC1_2 PF10046.9 KXS11178.1 - 0.26 11.6 3.2 0.54 10.6 0.8 2.1 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 OprB PF04966.12 KXS11178.1 - 0.35 10.2 1.3 0.54 9.6 1.3 1.3 1 0 0 1 1 1 0 Carbohydrate-selective porin, OprB family ACCA PF03255.14 KXS11178.1 - 0.45 10.4 1.6 0.75 9.7 1.6 1.4 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF2730 PF10805.8 KXS11178.1 - 0.74 9.9 2.9 1.9 8.6 1.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) NPV_P10 PF05531.12 KXS11178.1 - 1 9.9 4.2 2.3 8.8 1.9 2.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Wtap PF17098.5 KXS11178.1 - 1.3 9.0 7.3 1.7 8.6 4.7 2.0 1 1 1 2 2 2 0 WTAP/Mum2p family bZIP_2 PF07716.15 KXS11178.1 - 3.2 7.9 11.3 0.36 11.0 3.9 2.8 2 1 1 3 3 3 0 Basic region leucine zipper BCDHK_Adom3 PF10436.9 KXS11179.1 - 8.3e-32 110.3 0.0 1.1e-31 109.9 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KXS11179.1 - 1.6e-13 51.1 0.0 2.9e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KXS11179.1 - 0.00037 20.3 0.0 0.0016 18.2 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DEAD PF00270.29 KXS11180.1 - 2.6e-49 167.3 0.0 1.7e-48 164.7 0.0 2.2 2 1 1 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXS11180.1 - 1.9e-31 108.7 0.1 1e-30 106.4 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXS11180.1 - 4e-05 23.7 0.0 7.9e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 KXS11180.1 - 0.031 13.6 0.0 0.11 11.9 0.0 1.9 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit PRAI PF00697.22 KXS11180.1 - 0.052 13.3 0.1 0.091 12.5 0.1 1.3 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase DXP_reductoisom PF02670.16 KXS11180.1 - 0.17 12.6 0.1 1.7 9.3 0.1 2.2 2 0 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase BatA PF07584.11 KXS11182.1 - 0.098 13.0 0.1 0.45 10.9 0.1 2.1 1 0 0 1 1 1 0 Aerotolerance regulator N-terminal MFS_1 PF07690.16 KXS11182.1 - 0.6 9.0 30.9 1.5 7.7 18.6 3.3 3 1 1 4 4 4 0 Major Facilitator Superfamily bZIP_Maf PF03131.17 KXS11183.1 - 0.0061 17.1 14.4 0.01 16.3 14.4 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_1 PF00170.21 KXS11183.1 - 0.02 15.0 14.8 0.04 14.0 14.8 1.5 1 1 0 1 1 1 0 bZIP transcription factor bZIP_2 PF07716.15 KXS11183.1 - 0.021 14.9 16.9 2.7 8.2 16.9 2.3 1 1 0 1 1 1 0 Basic region leucine zipper SlyX PF04102.12 KXS11183.1 - 0.12 13.0 1.8 0.45 11.2 1.8 2.0 1 0 0 1 1 1 0 SlyX ATG16 PF08614.11 KXS11183.1 - 1.9 8.7 17.1 0.049 13.9 10.2 1.8 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF5401 PF17380.2 KXS11183.1 - 4.9 5.1 10.4 7.4 4.5 10.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) Caleosin PF05042.13 KXS11184.1 - 1.6e-09 37.9 0.1 2.1e-09 37.5 0.1 1.1 1 0 0 1 1 1 1 Caleosin related protein Caleosin PF05042.13 KXS11185.1 - 1.9e-40 138.6 0.0 2.1e-40 138.5 0.0 1.0 1 0 0 1 1 1 1 Caleosin related protein CENP-N PF05238.13 KXS11187.1 - 0.13 11.5 0.0 0.16 11.2 0.0 1.1 1 0 0 1 1 1 0 Kinetochore protein CHL4 like DUF2408 PF10303.9 KXS11189.1 - 2.6e-31 109.0 0.0 4.5e-25 88.8 0.0 3.5 3 1 0 3 3 3 2 Protein of unknown function (DUF2408) TauD PF02668.16 KXS11190.1 - 2.7e-29 102.8 0.0 3.7e-29 102.3 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 KXS11190.1 - 0.062 12.4 0.0 0.098 11.7 0.0 1.2 1 0 0 1 1 1 0 CsiD Methyltransf_16 PF10294.9 KXS11192.1 - 6.2e-19 68.4 0.0 9.7e-19 67.8 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 KXS11192.1 - 3.3e-05 23.4 0.0 5.1e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 KXS11192.1 - 0.00096 19.0 0.0 0.0015 18.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXS11192.1 - 0.003 18.2 0.0 0.0074 17.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXS11192.1 - 0.0039 17.9 0.0 0.016 15.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXS11192.1 - 0.0044 16.8 0.0 0.011 15.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXS11192.1 - 0.021 14.3 0.0 0.033 13.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Ank_3 PF13606.6 KXS11193.1 - 0.068 13.8 0.1 10 7.1 0.0 3.0 3 0 0 3 3 3 0 Ankyrin repeat Ank_3 PF13606.6 KXS11194.1 - 0.0018 18.6 0.2 0.83 10.4 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 KXS11194.1 - 0.041 14.2 0.1 9.3 6.7 0.0 3.0 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXS11194.1 - 0.086 13.4 0.0 0.59 10.8 0.0 2.3 2 1 0 2 2 2 0 Ankyrin repeats (3 copies) CBFD_NFYB_HMF PF00808.23 KXS11196.1 - 1.9e-15 56.9 0.1 1.9e-15 56.9 0.1 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KXS11196.1 - 0.00014 22.2 0.0 0.00029 21.2 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 FoP_duplication PF13865.6 KXS11196.1 - 0.012 16.1 17.0 0.012 16.1 17.0 2.3 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 Ank_4 PF13637.6 KXS11197.1 - 0.019 15.5 0.0 6.2 7.5 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank PF00023.30 KXS11197.1 - 0.024 15.1 0.0 0.42 11.1 0.0 2.8 3 0 0 3 3 3 0 Ankyrin repeat Ank_3 PF13606.6 KXS11197.1 - 0.037 14.6 0.0 2.5 8.9 0.0 2.9 3 0 0 3 3 3 0 Ankyrin repeat Ank_2 PF12796.7 KXS11197.1 - 0.13 12.9 0.0 0.24 12.0 0.0 1.4 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) HMG_CoA_synt_C PF08540.10 KXS11198.1 - 3.6e-95 318.8 0.0 4.7e-95 318.4 0.0 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 KXS11198.1 - 5.2e-90 300.0 0.2 7.1e-90 299.5 0.2 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal ACP_syn_III_C PF08541.10 KXS11198.1 - 0.096 12.9 0.0 11 6.3 0.0 2.4 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Rdx PF10262.9 KXS11200.1 - 0.089 13.0 0.0 0.15 12.3 0.0 1.3 1 0 0 1 1 1 0 Rdx family DUF2722 PF10846.8 KXS11201.1 - 0.066 12.2 0.6 0.11 11.4 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Arm PF00514.23 KXS11201.1 - 0.17 12.0 5.3 25 5.1 0.1 5.5 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat Ank_2 PF12796.7 KXS11202.1 - 2.6e-09 37.6 0.4 8.1e-09 36.0 0.3 1.8 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXS11202.1 - 0.00013 22.4 0.6 0.002 18.7 0.1 2.4 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXS11202.1 - 0.00028 21.1 1.9 0.035 14.4 0.0 2.8 2 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXS11202.1 - 0.00095 19.5 1.3 0.16 12.6 0.0 3.7 4 0 0 4 4 4 1 Ankyrin repeat DUF742 PF05331.11 KXS11202.1 - 0.085 12.7 0.6 1.3 8.9 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF742) Ank PF00023.30 KXS11202.1 - 0.11 13.0 4.0 0.83 10.2 0.0 3.3 3 2 1 4 4 4 0 Ankyrin repeat E1-E2_ATPase PF00122.20 KXS11204.1 - 7.7e-11 41.8 0.0 1.3e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_N PF00690.26 KXS11204.1 - 0.0039 16.8 0.0 0.011 15.4 0.0 1.7 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus E1-E2_ATPase PF00122.20 KXS11205.1 - 2.5e-06 27.1 1.6 2.5e-06 27.1 1.6 2.2 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 KXS11205.1 - 0.0076 16.6 0.4 0.02 15.2 0.4 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF4604 PF15377.6 KXS11205.1 - 0.022 15.2 0.5 0.033 14.6 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) RNA_pol PF00940.19 KXS11206.1 - 1.4e-157 524.8 0.0 1.9e-157 524.4 0.0 1.2 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 KXS11206.1 - 1.8e-23 83.5 0.0 3.2e-23 82.7 0.0 1.4 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal zf-RING_2 PF13639.6 KXS11207.1 - 2.3e-10 40.7 6.6 3.3e-09 36.9 1.5 2.7 2 1 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 KXS11207.1 - 8.6e-05 22.7 3.7 8.6e-05 22.7 3.7 2.9 2 2 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KXS11207.1 - 0.00034 20.4 4.2 0.00034 20.4 4.2 3.4 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KXS11207.1 - 0.03 14.2 4.0 1.2 9.0 0.2 3.1 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 KXS11207.1 - 0.038 13.8 10.5 0.2 11.6 4.6 3.0 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXS11207.1 - 0.05 13.5 3.7 0.16 11.9 0.5 2.9 3 1 0 3 3 2 0 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.7 KXS11207.1 - 0.062 13.4 1.0 0.062 13.4 1.0 1.7 2 0 0 2 2 1 0 RING-variant domain zf-P11 PF03854.14 KXS11207.1 - 0.075 12.7 0.0 0.075 12.7 0.0 2.3 3 0 0 3 3 3 0 P-11 zinc finger zf-RING_5 PF14634.6 KXS11207.1 - 0.096 12.7 3.9 0.77 9.8 1.2 2.7 2 1 0 2 2 2 0 zinc-RING finger domain Rad50_zn_hook PF04423.14 KXS11207.1 - 0.12 12.2 3.7 12 5.9 0.0 3.1 3 0 0 3 3 3 0 Rad50 zinc hook motif zf-RING_UBOX PF13445.6 KXS11207.1 - 0.17 12.0 4.6 1.4 9.0 0.2 3.7 2 2 1 3 3 3 0 RING-type zinc-finger DUF983 PF06170.12 KXS11207.1 - 0.17 12.3 0.1 6.5 7.2 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF983) zf-ANAPC11 PF12861.7 KXS11207.1 - 0.34 11.0 3.8 0.39 10.8 0.5 2.6 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_1 PF14446.6 KXS11207.1 - 0.35 10.8 6.3 3 7.9 0.1 3.6 3 1 1 4 4 4 0 Prokaryotic RING finger family 1 Zn_ribbon_17 PF17120.5 KXS11207.1 - 0.46 10.1 3.9 0.29 10.8 0.8 2.1 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 KXS11207.1 - 2.9 8.1 4.6 1.9 8.8 0.6 2.5 2 2 0 2 2 2 0 FANCL C-terminal domain zf-WRNIP1_ubi PF18279.1 KXS11207.1 - 9.5 7.1 8.1 58 4.7 0.3 3.6 3 0 0 3 3 3 0 Werner helicase-interacting protein 1 ubiquitin-binding domain CitMHS_2 PF16980.5 KXS11208.1 - 0.0024 16.6 0.5 0.0025 16.5 0.5 1.0 1 0 0 1 1 1 1 Putative citrate transport ADP_ribosyl_GH PF03747.14 KXS11209.1 - 0.0013 18.5 0.1 0.0014 18.5 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase Glyco_transf_10 PF00852.19 KXS11210.1 - 5.5e-30 104.4 0.8 9.9e-30 103.6 0.8 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 KXS11210.1 - 3.3e-07 30.7 0.2 9e-06 26.1 0.0 2.2 2 0 0 2 2 2 1 Fucosyltransferase, N-terminal Fungal_trans PF04082.18 KXS11211.1 - 1.2e-09 37.6 0.0 1.9e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXS11211.1 - 3.8e-06 26.9 8.9 3.8e-06 26.9 8.9 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Astro_capsid_p PF12226.8 KXS11211.1 - 0.22 10.6 3.9 0.37 9.9 3.9 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Nop14 PF04147.12 KXS11211.1 - 5.3 5.1 6.1 8 4.5 6.1 1.1 1 0 0 1 1 1 0 Nop14-like family Globin PF00042.22 KXS11212.1 - 0.00045 20.7 0.0 0.00067 20.2 0.0 1.3 1 0 0 1 1 1 1 Globin Arteri_GP4 PF02497.15 KXS11212.1 - 0.025 14.7 0.0 0.067 13.3 0.0 1.6 1 1 0 1 1 1 0 Arterivirus glycoprotein Protoglobin PF11563.8 KXS11212.1 - 0.028 14.3 0.0 0.081 12.8 0.0 1.7 1 1 0 1 1 1 0 Protoglobin BNR PF02012.20 KXS11212.1 - 0.14 12.2 0.8 0.19 11.8 0.0 1.7 2 0 0 2 2 2 0 BNR/Asp-box repeat Cupin_8 PF13621.6 KXS11213.1 - 2.4e-19 70.1 0.0 4.2e-19 69.3 0.0 1.4 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 KXS11213.1 - 1e-05 25.2 0.1 1.9e-05 24.3 0.1 1.3 1 0 0 1 1 1 1 Cupin superfamily protein zf-C2H2_aberr PF17017.5 KXS11216.1 - 3.5e-08 33.8 4.0 0.0005 20.3 0.7 2.1 1 1 1 2 2 2 2 Aberrant zinc-finger zf-C2H2 PF00096.26 KXS11216.1 - 1.1e-06 28.8 4.4 0.014 15.9 0.6 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXS11216.1 - 9.9e-05 22.9 2.9 0.19 12.6 0.2 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf_Hakai PF18408.1 KXS11216.1 - 0.016 14.9 0.2 5.6 6.8 0.0 2.2 2 0 0 2 2 2 0 C2H2 Hakai zinc finger domain zf_C2H2_ZHX PF18387.1 KXS11216.1 - 0.019 14.6 1.1 3.8 7.2 0.1 2.2 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_jaz PF12171.8 KXS11216.1 - 0.1 12.9 0.0 24 5.4 0.0 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.15 KXS11216.1 - 0.18 11.8 4.1 1 9.4 0.3 2.3 2 0 0 2 2 2 0 BED zinc finger A_deaminase PF00962.22 KXS11217.1 - 4.4e-22 78.8 0.0 7.4e-22 78.1 0.0 1.3 1 1 0 1 1 1 1 Adenosine/AMP deaminase Phos_pyr_kin PF08543.12 KXS11218.1 - 9.4e-70 234.8 0.1 1.6e-47 162.0 0.0 3.5 2 1 1 3 3 3 3 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.16 KXS11218.1 - 2.4e-38 132.1 0.1 2.3e-36 125.6 0.1 2.3 1 1 0 1 1 1 1 TENA/THI-4/PQQC family Pkinase PF00069.25 KXS11220.1 - 3.2e-64 216.9 0.0 2e-63 214.2 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS11220.1 - 3.5e-34 118.2 0.0 1.5e-33 116.2 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXS11220.1 - 3.5e-05 23.8 0.3 0.0054 16.7 0.0 2.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KXS11220.1 - 0.0011 18.7 0.0 0.0018 17.9 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kinase-like PF14531.6 KXS11220.1 - 0.0046 16.3 0.0 0.41 9.9 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 KXS11220.1 - 0.0074 15.7 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KXS11220.1 - 0.17 10.8 0.0 0.24 10.3 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Spherulin4 PF12138.8 KXS11222.1 - 2.2e-33 115.9 0.0 4.8e-33 114.8 0.0 1.6 1 1 0 1 1 1 1 Spherulation-specific family 4 Pkinase PF00069.25 KXS11223.1 - 3.3e-63 213.5 0.0 1.5e-33 116.3 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXS11223.1 - 2.4e-21 76.2 0.0 2.3e-14 53.3 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 KXS11223.1 - 0.04 13.3 0.0 0.083 12.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXS11223.1 - 0.062 13.2 0.1 1.8 8.4 0.1 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.6 KXS11223.1 - 0.075 12.3 0.0 6.7 5.9 0.0 2.1 2 0 0 2 2 2 0 Kinase-like Ribonuc_L-PSP PF01042.21 KXS11224.1 - 3.4e-33 114.2 0.0 4.1e-33 114.0 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP zf-RING_2 PF13639.6 KXS11226.1 - 2.1e-10 40.8 7.6 3.3e-10 40.1 7.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KXS11226.1 - 1.7e-07 30.8 3.0 1.7e-07 30.8 3.0 2.0 2 0 0 2 2 2 1 RING-like zinc finger zf-rbx1 PF12678.7 KXS11226.1 - 6e-07 29.7 4.3 1.1e-06 28.8 4.3 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KXS11226.1 - 1.1e-06 28.4 5.5 1.8e-06 27.7 5.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXS11226.1 - 5.5e-05 22.9 8.3 9.3e-05 22.2 8.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KXS11226.1 - 7.2e-05 22.8 4.2 0.00016 21.6 4.2 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 KXS11226.1 - 8.7e-05 22.4 4.1 0.00013 21.8 4.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KXS11226.1 - 0.00016 21.5 5.6 0.00025 20.8 5.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXS11226.1 - 0.004 17.1 2.8 0.004 17.1 2.8 2.2 2 0 0 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KXS11226.1 - 0.022 14.6 7.3 0.25 11.2 8.1 2.0 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 KXS11226.1 - 0.12 12.0 4.9 0.25 11.0 4.9 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 KXS11226.1 - 0.2 11.9 6.6 0.68 10.1 6.6 1.9 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 KXS11226.1 - 0.73 9.7 6.0 1.3 8.9 6.0 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.29 KXS11226.1 - 1.8 8.5 4.5 3.5 7.6 4.5 1.5 1 1 0 1 1 1 0 PHD-finger Zn_clus PF00172.18 KXS11228.1 - 1.5e-09 37.9 13.1 1.9e-09 37.5 13.1 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Rep_fac-A_C PF08646.10 KXS11228.1 - 4.9 6.9 7.0 5.6 6.7 7.0 1.1 1 0 0 1 1 1 0 Replication factor-A C terminal domain EF-hand_13 PF17958.1 KXS11229.1 - 3.8e-18 65.1 0.0 7.8e-18 64.1 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 KXS11229.1 - 2.8e-13 50.1 0.2 9.5e-12 45.2 0.0 3.0 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 KXS11229.1 - 2.4e-05 23.6 0.0 0.0031 17.0 0.1 2.7 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.6 KXS11229.1 - 4.6e-05 22.7 0.0 0.00012 21.4 0.0 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KXS11229.1 - 0.00017 21.2 0.2 0.0057 16.5 0.1 2.6 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.6 KXS11229.1 - 0.0061 16.4 0.1 0.039 13.8 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KXS11229.1 - 0.034 14.5 0.3 4.6 7.6 0.0 2.6 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region REF PF05755.12 KXS11229.1 - 0.057 13.2 0.0 0.099 12.5 0.0 1.2 1 0 0 1 1 1 0 Rubber elongation factor protein (REF) MelC1 PF06236.11 KXS11229.1 - 1.4 9.0 8.9 4 7.5 8.9 1.7 1 0 0 1 1 1 0 Tyrosinase co-factor MelC1 FHA PF00498.26 KXS11230.1 - 8.4e-16 58.1 0.0 1.7e-15 57.1 0.0 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KXS11230.1 - 0.00012 22.3 0.0 0.00037 20.8 0.0 1.8 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Med25_VWA PF11265.8 KXS11230.1 - 0.075 12.8 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Mediator complex subunit 25 von Willebrand factor type A OHCU_decarbox PF09349.10 KXS11231.1 - 8e-33 114.1 0.0 9.3e-33 113.9 0.0 1.1 1 0 0 1 1 1 1 OHCU decarboxylase Polysacc_deac_1 PF01522.21 KXS11232.1 - 5.3e-15 55.4 0.1 9.5e-15 54.6 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Ank_2 PF12796.7 KXS11233.1 - 4.9e-41 139.2 0.1 6.9e-17 61.8 0.1 4.2 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 KXS11233.1 - 1.3e-32 110.8 9.2 5.5e-06 26.6 0.1 7.0 6 1 1 7 7 7 6 Ankyrin repeat Ank_4 PF13637.6 KXS11233.1 - 1.3e-32 111.7 1.2 1e-07 32.3 0.1 6.2 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXS11233.1 - 4.2e-31 106.6 2.5 8e-09 35.6 0.1 5.3 4 1 1 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXS11233.1 - 4e-28 94.3 1.4 0.00047 20.4 0.0 7.0 7 0 0 7 7 7 5 Ankyrin repeat F-box-like PF12937.7 KXS11233.1 - 0.0003 20.6 0.1 0.00057 19.7 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXS11233.1 - 0.05 13.5 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 F-box domain CBFB_NFYA PF02045.15 KXS11234.1 - 9.6e-23 80.6 3.0 9.6e-23 80.6 3.0 1.7 2 0 0 2 2 2 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B LapA_dom PF06305.11 KXS11236.1 - 0.016 15.0 0.1 0.086 12.7 0.0 2.3 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain DUF3684 PF12449.8 KXS11237.1 - 6.2e-242 805.8 0.0 3.1e-240 800.2 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF3684) HATPase_c_3 PF13589.6 KXS11237.1 - 0.028 14.3 0.0 0.46 10.3 0.0 2.3 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase WLM PF08325.10 KXS11237.1 - 0.074 13.1 0.4 0.19 11.8 0.4 1.6 1 0 0 1 1 1 0 WLM domain CUE PF02845.16 KXS11237.1 - 0.14 11.9 0.1 0.36 10.6 0.1 1.7 1 0 0 1 1 1 0 CUE domain adh_short PF00106.25 KXS11238.1 - 1.1e-42 145.7 0.4 1.5e-42 145.3 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXS11238.1 - 1.2e-29 103.5 0.1 1.6e-29 103.2 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXS11238.1 - 5.8e-08 32.9 0.0 9.8e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KXS11238.1 - 0.02 14.3 0.0 0.3 10.4 0.0 2.1 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) Senescence PF06911.12 KXS11239.1 - 2e-05 25.0 1.2 2e-05 25.0 1.2 3.5 4 0 0 4 4 4 1 Senescence-associated protein DUF588 PF04535.12 KXS11239.1 - 2.3 8.0 5.2 1.3 8.8 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF588) MFS_1 PF07690.16 KXS11240.1 - 2.8e-25 89.0 12.7 3.1e-21 75.7 7.2 2.6 2 1 0 2 2 2 2 Major Facilitator Superfamily LacY_symp PF01306.19 KXS11240.1 - 0.0046 15.8 2.8 3 6.5 0.1 3.1 3 0 0 3 3 3 2 LacY proton/sugar symporter OATP PF03137.20 KXS11240.1 - 0.019 13.3 0.0 4.4 5.5 0.1 2.5 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family AAA_6 PF12774.7 KXS11241.1 - 3.6e-153 509.3 0.0 1.4e-152 507.4 0.0 2.0 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 KXS11241.1 - 1.8e-146 488.3 7.7 1.8e-146 488.3 7.7 2.6 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 KXS11241.1 - 2.2e-118 394.9 0.3 4.4e-117 390.7 0.0 2.6 3 0 0 3 3 3 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 KXS11241.1 - 6.4e-111 369.8 0.0 1.6e-110 368.5 0.0 1.7 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 KXS11241.1 - 1.6e-87 292.2 1.2 1.6e-87 292.2 1.2 2.7 3 0 0 3 3 3 1 ATP-binding dynein motor region AAA_7 PF12775.7 KXS11241.1 - 2.5e-87 291.1 0.0 1.1e-84 282.4 0.0 3.7 4 0 0 4 4 4 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 KXS11241.1 - 9.2e-64 214.2 0.0 2.2e-63 213.0 0.0 1.7 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 KXS11241.1 - 1.2e-57 195.6 8.2 1.2e-57 195.6 8.2 2.6 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 KXS11241.1 - 3.3e-45 153.0 0.0 3.7e-42 143.2 0.0 3.5 4 0 0 4 4 2 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 KXS11241.1 - 3.9e-32 111.0 0.0 5.1e-31 107.4 0.0 2.9 3 0 0 3 3 2 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 KXS11241.1 - 3.3e-22 79.0 0.0 7.4e-06 26.0 0.0 6.5 5 1 0 5 5 5 4 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 KXS11241.1 - 1.6e-19 69.9 0.1 7.3e-19 67.8 0.1 2.2 1 0 0 1 1 1 1 AAA+ lid domain AAA PF00004.29 KXS11241.1 - 7.8e-08 32.8 0.0 1.2 9.6 0.0 5.2 5 0 0 5 5 4 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KXS11241.1 - 4.5e-06 27.1 0.0 0.43 10.9 0.0 4.6 4 0 0 4 4 4 2 AAA ATPase domain AAA_22 PF13401.6 KXS11241.1 - 5.8e-06 26.6 0.0 1.6 9.0 0.0 4.8 4 0 0 4 4 4 1 AAA domain EF-hand_5 PF13202.6 KXS11241.1 - 0.00071 19.0 0.7 0.0023 17.3 0.7 1.9 1 0 0 1 1 1 1 EF hand RNA_helicase PF00910.22 KXS11241.1 - 0.0051 17.2 0.0 7.5 7.0 0.0 3.7 3 0 0 3 3 3 0 RNA helicase EF-hand_1 PF00036.32 KXS11241.1 - 0.0057 16.1 1.1 0.027 14.0 1.1 2.2 1 0 0 1 1 1 1 EF hand AAA_18 PF13238.6 KXS11241.1 - 0.0079 16.7 0.3 2.8 8.5 0.0 4.3 4 0 0 4 4 4 1 AAA domain Mg_chelatase PF01078.21 KXS11241.1 - 0.012 15.0 0.1 4.5 6.6 0.0 3.2 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI EF-hand_6 PF13405.6 KXS11241.1 - 0.02 14.8 1.0 0.1 12.6 1.0 2.3 1 0 0 1 1 1 0 EF-hand domain DUF815 PF05673.13 KXS11241.1 - 0.025 13.8 1.0 2.1 7.4 0.0 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF815) AAA_33 PF13671.6 KXS11241.1 - 0.051 13.7 0.0 27 4.9 0.0 3.8 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.6 KXS11241.1 - 0.08 12.7 0.1 5.5 6.7 0.0 3.2 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.27 KXS11241.1 - 0.097 13.2 0.8 21 5.6 0.0 3.8 4 0 0 4 4 3 0 ABC transporter AAA_29 PF13555.6 KXS11241.1 - 0.099 12.4 0.1 11 5.8 0.0 3.4 3 0 0 3 3 3 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 KXS11241.1 - 0.28 10.5 0.8 11 5.2 0.0 3.5 4 0 0 4 4 4 0 FtsK/SpoIIIE family DUF2730 PF10805.8 KXS11241.1 - 0.88 9.7 9.4 39 4.4 0.3 4.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2730) Sec34 PF04136.15 KXS11241.1 - 0.9 9.4 11.3 40 4.1 1.1 5.6 5 0 0 5 5 5 0 Sec34-like family AAA_30 PF13604.6 KXS11241.1 - 1.8 8.2 11.0 1.3 8.7 0.1 4.4 5 0 0 5 5 5 0 AAA domain Vps5 PF09325.10 KXS11241.1 - 4.5 6.8 12.0 0.19 11.2 1.1 3.2 4 0 0 4 4 3 0 Vps5 C terminal like Spc7 PF08317.11 KXS11241.1 - 8.8 5.1 37.6 0.063 12.2 3.1 4.0 4 0 0 4 4 3 0 Spc7 kinetochore protein LigB PF02900.18 KXS11242.1 - 6.7e-27 94.2 0.0 8.9e-27 93.8 0.0 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase SH3_9 PF14604.6 KXS11243.1 - 0.00017 21.3 0.0 0.0005 19.9 0.0 1.7 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 KXS11243.1 - 0.00048 19.7 0.0 0.00092 18.8 0.0 1.4 1 0 0 1 1 1 1 SH3 domain DUF2613 PF11021.8 KXS11243.1 - 0.044 13.9 0.5 0.11 12.6 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) SH3_2 PF07653.17 KXS11243.1 - 0.17 11.6 0.0 0.33 10.7 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain Aa_trans PF01490.18 KXS11244.1 - 7.5e-27 94.1 8.0 1.1e-26 93.6 8.0 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein SNARE_assoc PF09335.11 KXS11245.1 - 1.3e-14 54.8 9.8 2.2e-14 54.0 7.0 2.5 2 0 0 2 2 2 1 SNARE associated Golgi protein DUF805 PF05656.14 KXS11245.1 - 0.099 13.1 6.0 0.25 11.7 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF805) Spherulin4 PF12138.8 KXS11246.1 - 2.9e-41 141.7 0.0 8.8e-41 140.1 0.0 1.8 1 1 0 1 1 1 1 Spherulation-specific family 4 DUF5419 PF17441.2 KXS11246.1 - 0.0032 17.5 1.7 1.2 9.3 0.1 2.7 2 0 0 2 2 2 2 Family of unknown function (DUF5419) F-box-like PF12937.7 KXS11247.1 - 7.1e-07 29.0 0.6 1.5e-06 28.0 0.6 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXS11247.1 - 0.00082 19.2 0.0 0.0019 18.0 0.0 1.7 1 0 0 1 1 1 1 F-box domain SH3_1 PF00018.28 KXS11249.1 - 4.9e-08 32.5 0.1 8.8e-08 31.6 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KXS11249.1 - 4.6e-06 26.4 0.0 8.8e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain PTP_tm PF18861.1 KXS11249.1 - 0.0017 18.4 0.6 0.0026 17.8 0.6 1.2 1 0 0 1 1 1 1 Transmembrane domain of protein tyrosine phosphatase, receptor type J SKG6 PF08693.10 KXS11249.1 - 0.04 13.3 7.1 0.075 12.5 7.1 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Podoplanin PF05808.11 KXS11249.1 - 0.094 12.8 0.3 0.17 12.0 0.3 1.4 1 0 0 1 1 1 0 Podoplanin VSP PF03302.13 KXS11249.1 - 0.21 10.4 1.4 0.31 9.8 1.4 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein SH3_9 PF14604.6 KXS11250.1 - 9.6e-08 31.8 0.1 1.6e-07 31.0 0.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXS11250.1 - 3.1e-07 29.9 0.3 5.1e-07 29.2 0.3 1.3 1 0 0 1 1 1 1 SH3 domain Insulin_TMD PF17870.1 KXS11250.1 - 0.044 13.9 0.0 0.088 12.9 0.0 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment SH3_2 PF07653.17 KXS11250.1 - 0.076 12.7 0.1 0.15 11.8 0.1 1.4 1 0 0 1 1 1 0 Variant SH3 domain Amnionless PF14828.6 KXS11250.1 - 0.13 11.0 0.0 0.18 10.6 0.0 1.1 1 0 0 1 1 1 0 Amnionless TPR_19 PF14559.6 KXS11251.1 - 0.00046 20.6 0.0 0.93 10.0 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_4 PF07721.14 KXS11251.1 - 0.01 16.4 6.4 5.6 7.9 0.2 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 KXS11251.1 - 0.014 16.2 0.4 56 5.0 0.0 4.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 KXS11251.1 - 0.031 14.4 0.0 22 5.5 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Acetyltransf_6 PF13480.7 KXS11251.1 - 0.046 13.9 0.0 0.15 12.2 0.0 1.9 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain SH2 PF00017.24 KXS11251.1 - 0.059 13.5 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 SH2 domain TPR_12 PF13424.6 KXS11251.1 - 0.1 12.9 0.0 9.3 6.6 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat AAA_lid_4 PF17864.1 KXS11251.1 - 0.12 12.2 0.0 2.6 7.9 0.0 2.5 2 0 0 2 2 2 0 RuvB AAA lid domain Haspin_kinase PF12330.8 KXS11253.1 - 1.6e-54 185.3 0.0 2.2e-54 184.8 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Beta-lactamase PF00144.24 KXS11254.1 - 8e-32 110.8 3.3 1.6e-31 109.8 3.3 1.4 1 0 0 1 1 1 1 Beta-lactamase CDC45 PF02724.14 KXS11254.1 - 3.2 5.9 13.3 4.6 5.4 13.3 1.1 1 0 0 1 1 1 0 CDC45-like protein PseudoU_synth_2 PF00849.22 KXS11255.1 - 6.5e-19 68.6 0.0 1.4e-17 64.3 0.0 2.1 2 0 0 2 2 2 1 RNA pseudouridylate synthase p450 PF00067.22 KXS11256.1 - 3.7e-74 250.1 0.0 5.2e-74 249.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Parathyroid PF01279.17 KXS11256.1 - 0.12 13.0 0.3 0.45 11.1 0.1 2.0 2 0 0 2 2 2 0 Parathyroid hormone family PhyH PF05721.13 KXS11257.1 - 0.00029 21.2 0.1 0.00087 19.6 0.1 1.8 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) FG-GAP PF01839.23 KXS11260.1 - 0.00082 19.4 0.2 0.0023 18.0 0.2 1.8 1 0 0 1 1 1 1 FG-GAP repeat Furin-like PF00757.20 KXS11260.1 - 0.051 13.4 0.2 0.12 12.2 0.2 1.5 1 0 0 1 1 1 0 Furin-like cysteine rich region ABC_tran PF00005.27 KXS11261.1 - 1.4e-35 122.8 0.0 2e-20 73.7 0.0 2.7 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KXS11261.1 - 2.4e-17 63.7 8.8 8e-09 35.7 0.1 4.2 2 2 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KXS11261.1 - 1.3e-07 31.3 0.0 0.0012 18.5 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.19 KXS11261.1 - 2.9e-05 23.6 0.0 0.75 9.2 0.0 3.4 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain Ploopntkinase1 PF18748.1 KXS11261.1 - 0.0001 21.9 0.0 0.053 13.0 0.0 2.3 2 0 0 2 2 2 2 P-loop Nucleotide Kinase1 MMR_HSR1 PF01926.23 KXS11261.1 - 0.00041 20.4 0.0 0.39 10.8 0.1 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.6 KXS11261.1 - 0.00047 20.5 0.0 1.6 9.0 0.0 2.8 3 1 0 3 3 2 2 AAA domain Dynamin_N PF00350.23 KXS11261.1 - 0.00059 19.9 0.9 0.24 11.4 0.1 2.5 3 0 0 3 3 2 1 Dynamin family AAA_33 PF13671.6 KXS11261.1 - 0.001 19.3 0.0 2.5 8.3 0.0 2.7 2 1 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KXS11261.1 - 0.0011 18.9 0.0 0.68 9.8 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_18 PF13238.6 KXS11261.1 - 0.0065 17.0 0.0 1.7 9.2 0.0 2.7 3 0 0 3 3 2 1 AAA domain AAA_23 PF13476.6 KXS11261.1 - 0.0094 16.5 0.0 0.14 12.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 KXS11261.1 - 0.012 15.8 0.0 1.1 9.5 0.0 2.6 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit NACHT PF05729.12 KXS11261.1 - 0.016 15.1 0.1 1.9 8.4 0.0 3.6 4 0 0 4 4 4 0 NACHT domain IstB_IS21 PF01695.17 KXS11261.1 - 0.028 14.2 0.0 2.9 7.6 0.0 2.6 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_16 PF13191.6 KXS11261.1 - 0.052 13.9 0.0 8.8 6.7 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain AAA_28 PF13521.6 KXS11261.1 - 0.078 13.2 0.0 3 8.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 KXS11261.1 - 0.078 12.7 0.1 0.31 10.7 0.1 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_25 PF13481.6 KXS11261.1 - 0.099 12.2 0.1 2.8 7.5 0.0 3.0 3 0 0 3 3 3 0 AAA domain cobW PF02492.19 KXS11261.1 - 0.12 12.0 0.1 7.9 6.0 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF87 PF01935.17 KXS11261.1 - 0.17 11.9 0.0 8.8 6.3 0.0 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_7 PF12775.7 KXS11261.1 - 0.18 11.3 0.0 19 4.7 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region CRCB PF02537.15 KXS11262.1 - 6.7e-29 100.1 16.9 4e-18 65.5 5.4 2.7 2 1 0 2 2 2 2 CrcB-like protein, Camphor Resistance (CrcB) DUF5419 PF17441.2 KXS11263.1 - 0.37 10.9 5.3 8 6.7 0.2 3.3 3 0 0 3 3 3 0 Family of unknown function (DUF5419) Pectinesterase PF01095.19 KXS11264.1 - 4e-128 426.3 47.3 8.5e-45 152.7 6.9 4.7 5 0 0 5 5 5 4 Pectinesterase Pectate_lyase_3 PF12708.7 KXS11264.1 - 7e-17 62.0 48.8 1e-08 35.3 7.8 5.2 4 2 0 4 4 4 3 Pectate lyase superfamily protein Glyco_transf_7N PF13733.6 KXS11264.1 - 0.12 12.1 0.4 26 4.4 0.0 3.3 3 0 0 3 3 3 0 N-terminal region of glycosyl transferase group 7 DUF3737 PF12541.8 KXS11264.1 - 0.2 10.8 4.1 5.9 6.0 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3737) MARVEL PF01284.23 KXS11265.1 - 0.038 14.0 10.8 0.059 13.4 4.8 2.2 1 1 1 2 2 2 0 Membrane-associating domain Halogen_Hydrol PF10112.9 KXS11265.1 - 6.1 6.8 5.5 6.4 6.7 0.1 2.0 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Prismane PF03063.20 KXS11268.1 - 1.1e-130 436.8 0.0 1.4e-130 436.4 0.0 1.1 1 0 0 1 1 1 1 Prismane/CO dehydrogenase family FAD_binding_1 PF00667.20 KXS11268.1 - 6.7e-32 110.9 0.0 1.1e-31 110.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KXS11268.1 - 4e-25 88.7 0.0 8.4e-24 84.4 0.0 2.4 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.21 KXS11268.1 - 0.13 12.9 0.0 0.38 11.4 0.0 1.8 1 0 0 1 1 1 0 Oxidoreductase NAD-binding domain Pkinase PF00069.25 KXS11269.1 - 5e-52 176.9 0.0 6.6e-52 176.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS11269.1 - 5.6e-19 68.4 0.0 9.5e-19 67.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXS11269.1 - 2.6e-07 30.2 0.0 2.7e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KXS11269.1 - 0.00053 20.0 0.2 0.0019 18.2 0.1 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXS11269.1 - 0.0033 16.3 0.0 0.0041 16.0 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 KXS11269.1 - 0.0068 16.0 0.1 0.012 15.2 0.1 1.4 1 0 0 1 1 1 1 RIO1 family Ribosomal_L2 PF00181.23 KXS11269.1 - 0.03 14.3 0.0 0.062 13.3 0.0 1.5 1 0 0 1 1 1 0 Ribosomal Proteins L2, RNA binding domain FTA2 PF13095.6 KXS11269.1 - 0.058 13.0 0.0 0.087 12.4 0.0 1.2 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 KXS11269.1 - 0.086 11.8 0.0 0.12 11.3 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 KXS11269.1 - 0.092 12.1 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TauD PF02668.16 KXS11270.1 - 6.7e-55 186.8 3.3 9e-55 186.3 3.3 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DAGAT PF03982.13 KXS11271.1 - 1.8e-58 197.8 0.0 7.6e-43 146.5 0.0 2.0 2 0 0 2 2 2 2 Diacylglycerol acyltransferase CitMHS PF03600.16 KXS11272.1 - 0.043 13.0 2.1 0.052 12.7 2.1 1.1 1 0 0 1 1 1 0 Citrate transporter PALP PF00291.25 KXS11273.1 - 1.6e-80 270.7 0.0 2e-80 270.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 KXS11273.1 - 1.2e-23 82.6 0.0 1.4e-10 40.8 0.0 2.4 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase Imm6 PF14434.6 KXS11273.1 - 0.17 11.8 0.0 0.41 10.6 0.0 1.6 1 0 0 1 1 1 0 Immunity protein Imm6 Ank_2 PF12796.7 KXS11276.1 - 5.8e-16 58.8 0.3 1.1e-15 57.9 0.3 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) SH3_1 PF00018.28 KXS11276.1 - 8.1e-16 57.4 0.2 1.4e-15 56.6 0.2 1.4 1 0 0 1 1 1 1 SH3 domain Ank PF00023.30 KXS11276.1 - 7.3e-15 54.7 1.3 0.00014 22.2 0.3 3.4 3 0 0 3 3 3 3 Ankyrin repeat SH3_9 PF14604.6 KXS11276.1 - 1.3e-14 53.7 0.2 2.1e-14 53.1 0.2 1.3 1 0 0 1 1 1 1 Variant SH3 domain Ank_4 PF13637.6 KXS11276.1 - 3.2e-14 53.1 0.7 7.4e-10 39.2 0.1 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXS11276.1 - 2.5e-13 49.9 2.3 5.7e-05 23.3 0.0 4.1 1 1 3 4 4 4 3 Ankyrin repeats (many copies) SH3_2 PF07653.17 KXS11276.1 - 1.6e-10 40.5 0.0 2.9e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Ank_3 PF13606.6 KXS11276.1 - 3e-10 39.4 0.5 0.012 16.1 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat SH3_3 PF08239.11 KXS11276.1 - 0.00015 21.9 0.2 0.00028 21.1 0.2 1.4 1 0 0 1 1 1 1 Bacterial SH3 domain EF-hand_7 PF13499.6 KXS11278.1 - 1.5e-09 38.2 0.3 1.9e-09 37.8 0.3 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 KXS11278.1 - 6.9e-07 28.4 0.2 0.023 14.2 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 KXS11278.1 - 8.6e-07 28.7 0.3 0.01 15.7 0.0 2.4 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KXS11278.1 - 2.4e-06 26.8 2.4 0.027 14.0 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 KXS11278.1 - 6.2e-06 25.7 1.1 0.0014 18.4 0.3 2.5 2 1 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 KXS11278.1 - 0.015 15.6 0.0 0.18 12.1 0.0 2.0 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KXS11278.1 - 0.027 14.4 0.6 4.1 7.4 0.0 2.2 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand FA_hydroxylase PF04116.13 KXS11279.1 - 2.7e-17 63.4 12.5 1.9e-09 38.0 3.8 2.1 2 0 0 2 2 2 2 Fatty acid hydroxylase superfamily COG5 PF10392.9 KXS11280.1 - 4e-16 59.4 10.4 6.5e-16 58.7 4.7 3.3 4 0 0 4 4 4 1 Golgi transport complex subunit 5 Vps51 PF08700.11 KXS11280.1 - 0.00066 19.7 0.7 0.022 14.8 0.6 2.7 2 0 0 2 2 2 1 Vps51/Vps67 COG2 PF06148.11 KXS11280.1 - 0.055 13.6 1.6 0.8 9.8 1.3 2.6 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Spc7 PF08317.11 KXS11280.1 - 0.057 12.3 0.7 0.11 11.3 0.7 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein MiaE_2 PF13794.6 KXS11280.1 - 0.088 12.5 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like Zw10 PF06248.13 KXS11280.1 - 0.14 10.7 0.8 0.22 10.1 0.8 1.2 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 Vps54_N PF10475.9 KXS11280.1 - 0.23 10.7 1.5 0.42 9.8 1.5 1.3 1 0 0 1 1 1 0 Vacuolar-sorting protein 54, of GARP complex ELO PF01151.18 KXS11281.1 - 3.3e-56 190.6 19.6 4e-56 190.3 19.6 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family RIC1 PF07064.13 KXS11282.1 - 6.1e-58 196.2 0.5 9.2e-58 195.6 0.5 1.3 1 0 0 1 1 1 1 RIC1 SUI1 PF01253.22 KXS11284.1 - 4.2e-25 88.1 0.2 5.7e-25 87.7 0.2 1.2 1 0 0 1 1 1 1 Translation initiation factor SUI1 TatD_DNase PF01026.21 KXS11286.1 - 2.1e-24 86.3 0.0 6.3e-19 68.3 0.0 2.3 2 0 0 2 2 2 2 TatD related DNase IBR PF01485.21 KXS11288.1 - 3.9e-19 68.6 31.2 7.3e-11 42.1 0.6 4.1 3 1 1 4 4 4 3 IBR domain, a half RING-finger domain SRAP PF02586.14 KXS11289.1 - 4.3e-56 189.9 0.0 1.1e-51 175.4 0.0 2.1 2 0 0 2 2 2 2 SOS response associated peptidase (SRAP) Herpes_pp85 PF04637.12 KXS11289.1 - 5.8 5.2 7.5 9.1 4.6 7.5 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) SH3_9 PF14604.6 KXS11291.1 - 1.2e-05 25.1 0.0 2.2e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXS11291.1 - 0.0004 19.9 0.0 0.0012 18.5 0.0 1.8 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 KXS11291.1 - 0.11 12.1 0.0 0.32 10.7 0.0 1.7 1 0 0 1 1 1 0 Variant SH3 domain SH3_1 PF00018.28 KXS11292.1 - 1.4e-10 40.6 0.0 9.2e-05 22.0 0.0 3.6 3 0 0 3 3 3 3 SH3 domain SH3_9 PF14604.6 KXS11292.1 - 2.5e-09 36.9 0.0 0.018 14.9 0.0 3.7 3 0 0 3 3 3 3 Variant SH3 domain SH3_2 PF07653.17 KXS11292.1 - 3.1e-06 26.8 0.0 0.92 9.2 0.1 3.5 3 0 0 3 3 3 3 Variant SH3 domain Il2rg PF15874.5 KXS11293.1 - 1.2e-16 60.8 0.1 3.1e-11 43.4 0.0 2.3 2 0 0 2 2 2 2 Putative Interleukin 2 receptor, gamma chain OGG_N PF07934.12 KXS11294.1 - 7.5e-32 110.0 0.2 1e-31 109.5 0.2 1.2 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 KXS11294.1 - 6.4e-12 45.9 0.0 1.2e-11 45.0 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 KXS11294.1 - 0.074 13.0 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif SH3_9 PF14604.6 KXS11295.1 - 1.4e-07 31.2 0.1 1.4e-07 31.2 0.1 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 KXS11295.1 - 0.00064 19.3 1.6 0.00083 18.9 0.0 2.0 2 0 0 2 2 2 1 SH3 domain Phage_holin_7_1 PF16081.5 KXS11295.1 - 0.076 13.2 2.0 0.14 12.4 2.0 1.4 1 0 0 1 1 1 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family TRAUB PF08164.12 KXS11297.1 - 1.9e-16 60.3 0.1 6.1e-16 58.7 0.0 1.9 2 0 0 2 2 2 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.6 KXS11297.1 - 1.7e-11 44.9 0.1 1.4e-10 42.0 0.0 2.4 2 1 0 2 2 2 1 Apoptosis antagonizing transcription factor Macoilin PF09726.9 KXS11297.1 - 0.11 11.1 0.6 0.12 10.9 0.6 1.1 1 0 0 1 1 1 0 Macoilin family Suf PF05843.14 KXS11297.1 - 0.13 12.2 0.1 0.21 11.5 0.1 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Nop14 PF04147.12 KXS11297.1 - 0.13 10.4 17.0 0.19 9.9 17.0 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 KXS11297.1 - 1.6 6.9 16.8 2.4 6.4 16.8 1.1 1 0 0 1 1 1 0 CDC45-like protein LAP1C PF05609.12 KXS11297.1 - 4.2 6.4 9.1 6 5.9 9.1 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) BUD22 PF09073.10 KXS11297.1 - 7.3 5.8 24.0 13 5.0 23.6 1.5 2 0 0 2 2 2 0 BUD22 Adaptin_N PF01602.20 KXS11298.1 - 9e-132 440.3 0.0 1e-131 440.1 0.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KXS11298.1 - 4.6e-08 33.3 0.0 0.00019 21.5 0.0 2.5 1 1 1 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KXS11298.1 - 5.8e-05 23.4 6.7 0.28 11.6 0.1 5.0 3 2 1 4 4 4 2 HEAT repeats HEAT PF02985.22 KXS11298.1 - 0.0028 17.8 3.6 13 6.3 0.1 5.1 5 0 0 5 5 5 1 HEAT repeat Arm PF00514.23 KXS11298.1 - 0.16 12.1 2.2 62 3.8 0.0 4.7 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Cmc1 PF08583.10 KXS11300.1 - 7e-17 61.2 2.2 9.7e-17 60.8 2.2 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.13 KXS11300.1 - 0.0058 16.7 2.5 0.02 15.1 2.5 1.9 1 1 0 1 1 1 1 CHCH domain NDUF_B7 PF05676.13 KXS11300.1 - 0.0069 16.1 1.3 0.011 15.5 1.3 1.4 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) CX9C PF16860.5 KXS11300.1 - 0.0088 16.0 0.8 0.018 15.1 0.8 1.4 1 0 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, OPT PF03169.15 KXS11301.1 - 4.6e-166 554.1 48.4 5.3e-166 553.8 48.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein TLD PF07534.16 KXS11303.1 - 1.4e-20 73.9 0.2 2.8e-20 73.0 0.2 1.5 1 0 0 1 1 1 1 TLD Miff PF05644.11 KXS11303.1 - 0.066 12.8 1.1 0.11 12.1 1.1 1.2 1 0 0 1 1 1 0 Mitochondrial and peroxisomal fission factor Mff GST_C_3 PF14497.6 KXS11304.1 - 8.1e-22 77.3 0.0 1.2e-21 76.8 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KXS11304.1 - 0.051 13.8 0.0 0.089 13.0 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Beach PF02138.18 KXS11307.1 - 9.6e-124 412.2 0.0 1.4e-123 411.7 0.0 1.3 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 KXS11307.1 - 2.5e-13 50.0 0.0 9.6e-13 48.1 0.0 2.0 2 0 0 2 2 2 1 PH domain associated with Beige/BEACH WD40 PF00400.32 KXS11307.1 - 4e-07 30.6 5.4 0.86 10.6 0.8 5.7 5 0 0 5 5 5 2 WD domain, G-beta repeat DEDD_Tnp_IS110 PF01548.17 KXS11307.1 - 0.17 11.8 0.0 0.34 10.8 0.0 1.4 1 0 0 1 1 1 0 Transposase ABC2_membrane PF01061.24 KXS11308.1 - 2.5e-35 121.8 20.9 2.5e-35 121.8 20.9 2.1 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 KXS11308.1 - 1.3e-25 90.5 0.0 2.2e-25 89.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KXS11308.1 - 0.0051 16.7 0.0 1.6 8.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system Calici_MSP PF05752.11 KXS11308.1 - 0.019 14.8 0.0 0.035 13.9 0.0 1.3 1 0 0 1 1 1 0 Calicivirus minor structural protein AAA_29 PF13555.6 KXS11308.1 - 0.051 13.3 0.4 0.16 11.8 0.4 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_28 PF13521.6 KXS11308.1 - 0.066 13.5 0.1 0.13 12.5 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KXS11308.1 - 0.09 12.3 0.0 0.4 10.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KXS11308.1 - 0.11 12.9 0.0 0.25 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain ABC2_membrane_3 PF12698.7 KXS11308.1 - 0.33 10.0 22.2 0.81 8.7 22.2 1.7 1 0 0 1 1 1 0 ABC-2 family transporter protein ATP-synt_ab PF00006.25 KXS11308.1 - 0.36 10.4 1.1 1.8 8.1 1.1 2.0 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Saf_2TM PF18303.1 KXS11308.1 - 1.1 8.9 4.5 4.5 6.8 0.1 3.1 3 0 0 3 3 3 0 SAVED-fused 2TM effector domain I_LWEQ PF01608.17 KXS11309.1 - 9e-39 133.2 135.3 1.4e-32 113.0 9.9 14.2 8 4 6 15 15 15 8 I/LWEQ domain FERM_M PF00373.18 KXS11309.1 - 2.1e-28 99.1 0.4 2.1e-28 99.1 0.4 2.6 3 0 0 3 3 3 1 FERM central domain Talin_middle PF09141.10 KXS11309.1 - 3e-28 98.9 3.3 3e-28 98.9 3.3 14.9 6 4 3 12 12 12 5 Talin, middle domain FERM_f0 PF16511.5 KXS11309.1 - 6.6e-18 64.8 0.1 8e-14 51.7 0.0 3.0 2 0 0 2 2 2 2 N-terminal or F0 domain of Talin-head FERM FERM_N PF09379.10 KXS11309.1 - 1.5e-13 50.5 0.0 3.9e-13 49.1 0.0 1.8 1 0 0 1 1 1 1 FERM N-terminal domain IRS PF02174.17 KXS11309.1 - 0.029 14.2 0.0 0.089 12.7 0.0 1.8 1 0 0 1 1 1 0 PTB domain (IRS-1 type) RA PF00788.23 KXS11309.1 - 0.061 14.0 0.2 0.16 12.6 0.2 1.7 1 0 0 1 1 1 0 Ras association (RalGDS/AF-6) domain ACBP PF00887.19 KXS11309.1 - 0.095 12.9 0.1 0.43 10.8 0.1 2.2 1 0 0 1 1 1 0 Acyl CoA binding protein Antimicrobial15 PF08110.12 KXS11309.1 - 0.99 9.8 4.3 5.6 7.4 1.4 3.5 2 0 0 2 2 2 0 Ocellatin family ParBc PF02195.18 KXS11310.1 - 0.00038 20.7 0.0 0.00065 19.9 0.0 1.3 1 0 0 1 1 1 1 ParB-like nuclease domain ODC_AZ PF02100.17 KXS11310.1 - 0.013 15.4 0.1 0.031 14.2 0.1 1.6 1 1 0 1 1 1 0 Ornithine decarboxylase antizyme DndB PF14072.6 KXS11310.1 - 0.026 13.7 0.0 0.029 13.6 0.0 1.1 1 0 0 1 1 1 0 DNA-sulfur modification-associated DUF262 PF03235.14 KXS11310.1 - 0.087 13.0 0.0 0.089 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF262 AflR PF08493.10 KXS11311.1 - 0.038 13.5 0.6 0.054 13.0 0.6 1.1 1 0 0 1 1 1 0 Aflatoxin regulatory protein Mit_ribos_Mrp51 PF11709.8 KXS11311.1 - 0.11 12.0 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal protein subunit SH3_9 PF14604.6 KXS11312.1 - 5.5e-08 32.5 0.1 1.6e-07 31.1 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 KXS11312.1 - 3.4e-06 26.6 0.0 6e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KXS11312.1 - 4.2e-05 23.1 0.0 8.7e-05 22.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain DUF1180 PF06679.12 KXS11312.1 - 0.28 11.6 16.7 0.89 10.0 8.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Stevor PF17410.2 KXS11312.1 - 0.36 10.3 4.1 0.53 9.8 4.1 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame SOG2 PF10428.9 KXS11312.1 - 0.58 9.3 11.6 0.96 8.6 11.6 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein DUF5305 PF17231.2 KXS11312.1 - 4.4 6.6 6.2 6.8 6.0 6.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5305) DUF3357 PF11837.8 KXS11312.1 - 7.1 7.1 8.3 0.56 10.7 0.8 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF3357) Ank_4 PF13637.6 KXS11313.1 - 4.7e-10 39.8 0.3 2.5e-08 34.3 0.1 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXS11313.1 - 1.4e-09 38.0 0.3 3e-07 30.6 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KXS11313.1 - 1.6e-09 37.7 1.8 1.2e-05 25.5 0.8 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 KXS11313.1 - 4e-08 33.7 0.0 1.2e-07 32.2 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXS11313.1 - 1.1e-07 31.5 0.5 0.00076 19.8 0.2 2.8 2 0 0 2 2 2 2 Ankyrin repeat DUF1664 PF07889.12 KXS11313.1 - 0.00062 19.8 32.1 0.0046 17.0 0.9 5.0 3 1 2 5 5 5 4 Protein of unknown function (DUF1664) ATG16 PF08614.11 KXS11313.1 - 4 7.6 69.2 1.7 8.8 16.4 5.3 1 1 3 4 4 4 0 Autophagy protein 16 (ATG16) A_deaminase PF00962.22 KXS11314.1 - 1.2e-62 212.2 0.0 1.5e-62 211.8 0.0 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase Dynamin_N PF00350.23 KXS11315.1 - 3e-05 24.1 0.0 4.1e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Dynamin family AAA_23 PF13476.6 KXS11315.1 - 0.1 13.1 0.0 0.11 13.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KXS11315.1 - 0.15 11.9 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KXS11315.1 - 0.19 11.6 0.0 0.23 11.4 0.0 1.1 1 0 0 1 1 1 0 RsgA GTPase HATPase_c_3 PF13589.6 KXS11317.1 - 1.4e-09 37.9 0.0 2.2e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KXS11317.1 - 1.6e-08 35.0 0.0 3.7e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase v110 PF01639.17 KXS11318.1 - 0.016 15.1 1.8 0.029 14.2 1.8 1.5 1 0 0 1 1 1 0 Viral family 110 p450 PF00067.22 KXS11319.1 - 4.4e-70 236.7 0.0 7.2e-70 236.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Tox-HNH-HHH PF15637.6 KXS11319.1 - 0.11 12.7 0.1 0.3 11.3 0.1 1.7 1 0 0 1 1 1 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif Ribosomal_L7Ae PF01248.26 KXS11321.1 - 3.5e-26 90.8 0.1 4.3e-26 90.5 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 KXS11321.1 - 0.0003 20.9 0.0 0.00034 20.7 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.6 KXS11321.1 - 0.00053 19.8 0.0 0.00076 19.3 0.0 1.2 1 0 0 1 1 1 1 PELOTA RNA binding domain Ank_3 PF13606.6 KXS11323.1 - 0.022 15.3 0.1 0.092 13.4 0.0 2.0 2 0 0 2 2 2 0 Ankyrin repeat SlyX PF04102.12 KXS11323.1 - 0.064 13.9 1.4 0.1 13.2 1.4 1.4 1 0 0 1 1 1 0 SlyX GIT_CC PF16559.5 KXS11323.1 - 0.1 12.5 0.1 0.19 11.6 0.1 1.4 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor ADIP PF11559.8 KXS11323.1 - 0.11 12.6 0.2 0.17 12.0 0.2 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding NAD_binding_8 PF13450.6 KXS11325.1 - 3.2e-08 33.7 0.0 6.8e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXS11325.1 - 1.1e-05 25.3 0.0 2.2e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXS11325.1 - 0.0024 17.1 0.0 0.24 10.6 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXS11325.1 - 0.0046 17.5 0.0 0.38 11.4 0.1 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KXS11325.1 - 0.064 12.5 0.1 0.11 11.8 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain TCR_zetazeta PF11628.8 KXS11325.1 - 0.1 12.3 0.1 0.23 11.1 0.1 1.6 1 0 0 1 1 1 0 T-cell surface glycoprotein CD3 zeta chain Pyr_redox_3 PF13738.6 KXS11325.1 - 0.24 10.6 0.0 3.1 7.0 0.1 2.7 3 1 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Metallophos PF00149.28 KXS11326.1 - 3.8e-10 40.6 0.4 5.7e-10 40.0 0.4 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PhoD PF09423.10 KXS11326.1 - 0.043 12.8 0.0 0.065 12.2 0.0 1.3 1 0 0 1 1 1 0 PhoD-like phosphatase Prok-JAB PF14464.6 KXS11326.1 - 0.085 12.6 0.6 0.18 11.6 0.1 1.8 2 0 0 2 2 2 0 Prokaryotic homologs of the JAB domain WD40 PF00400.32 KXS11327.1 - 1.2e-08 35.5 0.1 3e-08 34.2 0.1 1.7 1 0 0 1 1 1 1 WD domain, G-beta repeat Ank PF00023.30 KXS11328.1 - 0.0046 17.3 0.0 1.1 9.8 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeat THDPS_N_2 PF14805.6 KXS11328.1 - 0.12 12.6 0.1 0.81 10.0 0.0 2.4 2 0 0 2 2 2 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal HAD_2 PF13419.6 KXS11329.1 - 1.4e-20 74.1 0.0 1.8e-20 73.8 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KXS11329.1 - 1.1e-09 39.0 0.0 9.3e-08 32.6 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 KXS11329.1 - 0.00063 19.8 0.0 2 8.5 0.0 2.7 1 1 1 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KXS11329.1 - 0.0018 18.3 0.0 0.011 15.8 0.0 2.1 2 0 0 2 2 2 1 HAD-hyrolase-like Zn_clus PF00172.18 KXS11330.1 - 6.9e-07 29.3 11.0 1.3e-06 28.4 11.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.32 KXS11331.1 - 2.5e-13 50.2 4.8 0.00082 20.1 0.5 5.5 5 0 0 5 5 5 3 WD domain, G-beta repeat LisH PF08513.11 KXS11331.1 - 1.2e-05 25.1 0.1 2.2e-05 24.2 0.1 1.5 1 0 0 1 1 1 1 LisH ADH_zinc_N PF00107.26 KXS11332.1 - 4.9e-25 88.0 0.4 8.4e-25 87.2 0.4 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXS11332.1 - 2e-14 54.8 0.0 3.5e-14 54.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXS11332.1 - 3.9e-10 39.6 0.0 9.8e-10 38.3 0.0 1.7 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Mg_trans_NIPA PF05653.14 KXS11334.1 - 1.2e-85 287.3 17.3 1.4e-85 287.0 17.3 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 KXS11334.1 - 2e-05 24.8 2.5 2e-05 24.8 2.5 4.0 3 1 0 3 3 3 2 EamA-like transporter family DUF4064 PF13273.6 KXS11334.1 - 0.33 11.2 0.0 0.33 11.2 0.0 4.1 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) Hexokinase_2 PF03727.16 KXS11335.1 - 1.5e-70 237.4 0.0 2.2e-70 236.8 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 KXS11335.1 - 1.5e-61 207.8 0.0 1.6e-60 204.4 0.0 2.0 2 0 0 2 2 2 1 Hexokinase Abhydrolase_6 PF12697.7 KXS11336.1 - 2.4e-21 77.3 5.7 3.9e-21 76.7 5.7 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXS11336.1 - 1.8e-10 40.5 0.4 2.7e-10 39.9 0.4 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KXS11336.1 - 2e-06 27.6 0.0 9.1e-05 22.2 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.20 KXS11336.1 - 0.013 15.7 0.0 2.1 8.4 0.0 2.3 2 0 0 2 2 2 0 Thioesterase domain Ser_hydrolase PF06821.13 KXS11336.1 - 0.023 14.5 0.1 0.039 13.8 0.1 1.4 1 0 0 1 1 1 0 Serine hydrolase DUF2015 PF09435.10 KXS11337.1 - 3.3e-15 55.9 0.0 5e-15 55.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) CoA_binding_3 PF13727.6 KXS11337.1 - 0.067 13.2 0.0 0.1 12.6 0.0 1.2 1 0 0 1 1 1 0 CoA-binding domain Plasmod_MYXSPDY PF07981.11 KXS11338.1 - 0.065 13.2 0.8 0.13 12.3 0.8 1.5 1 0 0 1 1 1 0 Plasmodium repeat_MYXSPDY Cyclin PF08613.11 KXS11339.1 - 2.1e-06 28.2 0.1 7.5e-06 26.4 0.0 1.9 2 0 0 2 2 2 1 Cyclin COX7B PF05392.11 KXS11340.1 - 0.019 14.6 0.2 0.022 14.4 0.2 1.1 1 0 0 1 1 1 0 Cytochrome C oxidase chain VIIB DUF4200 PF13863.6 KXS11341.1 - 5.1e-25 88.2 15.3 5.1e-25 88.2 15.3 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4200) Phage_GP20 PF06810.11 KXS11341.1 - 0.025 14.4 2.7 0.025 14.4 2.7 2.6 2 1 0 2 2 2 0 Phage minor structural protein GP20 LMBR1 PF04791.16 KXS11341.1 - 0.043 12.7 4.2 0.048 12.6 4.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein CNP_C_terminal PF17839.1 KXS11341.1 - 0.044 14.5 2.3 1.1 10.1 0.0 3.3 3 1 1 4 4 4 0 C-terminal domain of cyclic nucleotide phosphodiesterase FliG_N PF14842.6 KXS11341.1 - 0.069 13.7 7.5 2.5 8.7 0.6 2.8 1 1 0 2 2 2 0 FliG N-terminal domain Peptidase_S46 PF10459.9 KXS11341.1 - 0.43 9.2 11.2 0.58 8.7 11.2 1.3 1 0 0 1 1 1 0 Peptidase S46 Spc7 PF08317.11 KXS11341.1 - 0.74 8.6 22.0 0.094 11.6 9.7 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein CCDC-167 PF15188.6 KXS11341.1 - 5.8 7.3 10.1 5.5 7.4 0.1 3.4 2 1 1 3 3 3 0 Coiled-coil domain-containing protein 167 DNA_primase_lrg PF04104.14 KXS11342.1 - 1.5e-85 286.8 0.0 2.2e-85 286.3 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit PAP2 PF01569.21 KXS11344.1 - 1.8e-11 43.9 0.0 6.2e-11 42.2 0.0 1.9 1 0 0 1 1 1 1 PAP2 superfamily PATR PF12951.7 KXS11344.1 - 8.3e-09 35.4 4.9 8.3e-09 35.4 4.9 2.8 3 0 0 3 3 3 1 Passenger-associated-transport-repeat Tropomyosin_1 PF12718.7 KXS11345.1 - 0.0021 18.2 5.7 0.0021 18.2 5.7 5.0 4 1 1 5 5 5 1 Tropomyosin like DUF2408 PF10303.9 KXS11345.1 - 0.89 10.1 26.6 0.12 12.9 10.2 4.7 3 2 2 5 5 5 0 Protein of unknown function (DUF2408) Peptidase_U57 PF05582.12 KXS11345.1 - 3.9 6.7 14.0 0.023 14.0 2.2 2.7 2 1 1 3 3 3 0 YabG peptidase U57 DUF4407 PF14362.6 KXS11345.1 - 7.1 5.9 42.6 0.012 15.0 4.6 3.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) rRNA_proc-arch PF13234.6 KXS11346.1 - 2.5e-72 244.1 0.0 6.2e-72 242.8 0.0 1.7 2 0 0 2 2 2 1 rRNA-processing arch domain DSHCT PF08148.12 KXS11346.1 - 1.9e-54 183.7 2.1 3.5e-54 182.9 2.1 1.4 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.29 KXS11346.1 - 1.6e-17 63.8 0.0 5.4e-17 62.1 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXS11346.1 - 1.2e-06 28.9 0.0 1.4e-05 25.3 0.0 2.7 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXS11346.1 - 7.1e-05 22.9 0.0 0.00018 21.6 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PIG-P PF08510.12 KXS11347.1 - 0.00025 20.9 0.1 0.00029 20.7 0.1 1.1 1 0 0 1 1 1 1 PIG-P START PF01852.19 KXS11347.1 - 0.079 12.4 0.0 0.081 12.3 0.0 1.1 1 0 0 1 1 1 0 START domain Methyltransf_16 PF10294.9 KXS11349.1 - 5.1e-23 81.7 0.0 7.4e-23 81.2 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 KXS11349.1 - 4.7e-06 26.2 0.1 6.7e-06 25.7 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Cons_hypoth95 PF03602.15 KXS11349.1 - 0.008 15.8 0.1 0.014 15.1 0.1 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_23 PF13489.6 KXS11349.1 - 0.014 15.2 0.0 0.031 14.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 KXS11349.1 - 0.016 15.9 0.1 0.086 13.6 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.14 KXS11349.1 - 0.043 13.3 0.1 0.077 12.5 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase small domain RPN6_N PF18055.1 KXS11349.1 - 0.19 12.1 0.0 0.43 10.9 0.0 1.5 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN6 N-terminal domain Bromo_TP PF07524.13 KXS11350.1 - 7.5e-17 61.1 0.0 1.2e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated Bromo_TP_like PF17027.5 KXS11350.1 - 0.081 13.1 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 Histone-fold protein DUF829 PF05705.14 KXS11351.1 - 9.8e-21 74.7 0.1 3.4e-20 73.0 0.1 1.9 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) HemY_N PF07219.13 KXS11351.1 - 0.24 11.6 2.2 0.41 10.8 2.2 1.3 1 0 0 1 1 1 0 HemY protein N-terminus GDPD PF03009.17 KXS11352.1 - 7.8e-16 58.6 0.0 1.5e-13 51.1 0.0 2.7 1 1 1 2 2 2 2 Glycerophosphoryl diester phosphodiesterase family Arm_3 PF16186.5 KXS11352.1 - 0.18 11.4 0.0 0.36 10.4 0.0 1.4 1 0 0 1 1 1 0 Atypical Arm repeat adh_short_C2 PF13561.6 KXS11353.1 - 1.6e-27 96.6 1.8 2.7e-15 56.6 0.4 3.8 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXS11353.1 - 1.9e-22 79.7 1.0 2.4e-16 59.8 0.4 2.8 1 1 1 2 2 2 2 short chain dehydrogenase KR PF08659.10 KXS11353.1 - 1.9e-06 27.9 0.0 2.8e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF1409 PF07197.12 KXS11353.1 - 0.12 12.3 0.0 0.87 9.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1409) F-box-like PF12937.7 KXS11354.1 - 0.016 15.0 0.0 0.041 13.8 0.0 1.7 1 0 0 1 1 1 0 F-box-like F-box PF00646.33 KXS11354.1 - 0.024 14.5 0.0 0.055 13.4 0.0 1.6 1 0 0 1 1 1 0 F-box domain HA2 PF04408.23 KXS11356.1 - 2.9e-23 82.2 0.0 7.6e-23 80.9 0.0 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KXS11356.1 - 6.9e-14 52.0 0.0 1.5e-13 50.9 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KXS11356.1 - 9e-13 48.5 0.0 2.1e-12 47.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KXS11356.1 - 2.3e-05 24.2 0.0 0.00011 22.0 0.0 2.0 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KXS11356.1 - 0.01 16.1 0.2 0.14 12.5 0.1 2.7 2 1 0 2 2 2 0 AAA domain T2SSE PF00437.20 KXS11356.1 - 0.015 14.4 0.0 0.032 13.3 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_19 PF13245.6 KXS11356.1 - 0.11 12.8 0.0 0.51 10.7 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KXS11356.1 - 0.17 11.6 0.1 0.49 10.2 0.0 1.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain Pkinase PF00069.25 KXS11357.1 - 4e-40 137.9 0.0 4.7e-40 137.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS11357.1 - 4.2e-16 59.0 0.0 5.6e-16 58.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase YrbL-PhoP_reg PF10707.9 KXS11357.1 - 0.12 11.8 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Mito_carr PF00153.27 KXS11358.1 - 2.7e-55 184.3 4.1 1.1e-18 67.0 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein PrcB_C PF14343.6 KXS11358.1 - 0.022 14.9 0.0 1 9.5 0.0 2.4 2 0 0 2 2 2 0 PrcB C-terminal MFS_1 PF07690.16 KXS11359.1 - 2e-23 82.9 19.1 2.2e-22 79.5 19.1 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KXS11359.1 - 6.3e-12 44.7 6.2 9.7e-12 44.1 6.2 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KXS11359.1 - 1.8e-08 33.7 3.1 1.8e-08 33.7 3.1 2.3 1 1 1 2 2 2 1 Sugar (and other) transporter EF1_GNE PF00736.19 KXS11361.1 - 1.1e-36 124.9 1.6 1.1e-36 124.9 1.6 2.0 2 0 0 2 2 2 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 KXS11361.1 - 2.2e-10 40.8 6.2 2.2e-10 40.8 6.2 2.8 3 0 0 3 3 3 1 Eukaryotic elongation factor 1 beta central acidic region HTH_33 PF13592.6 KXS11362.1 - 1e-07 31.5 0.0 2.1e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.6 KXS11362.1 - 0.00018 21.6 0.8 0.0018 18.4 0.0 2.6 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_23 PF13384.6 KXS11362.1 - 0.00072 19.3 0.1 0.0059 16.4 0.0 2.3 2 0 0 2 2 2 1 Homeodomain-like domain HTH_ABP1_N PF18107.1 KXS11362.1 - 0.00092 18.9 0.0 0.0019 17.9 0.0 1.5 1 0 0 1 1 1 1 Fission yeast centromere protein N-terminal domain HTH_29 PF13551.6 KXS11362.1 - 0.0077 16.2 0.1 0.029 14.4 0.0 2.1 2 0 0 2 2 2 1 Winged helix-turn helix HTH_Tnp_IS630 PF01710.16 KXS11362.1 - 0.017 15.2 0.2 0.031 14.3 0.2 1.4 1 1 0 1 1 1 0 Transposase HTH_17 PF12728.7 KXS11362.1 - 0.029 14.6 1.0 0.076 13.2 0.0 2.2 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_32 PF13565.6 KXS11362.1 - 0.031 14.9 1.1 0.23 12.1 0.0 2.4 2 1 1 3 3 3 0 Homeodomain-like domain Sporozoite_P67 PF05642.11 KXS11362.1 - 0.4 8.7 10.2 0.51 8.4 10.2 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SKG6 PF08693.10 KXS11362.1 - 2.3 7.7 8.0 4.2 6.9 8.0 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain F-box-like PF12937.7 KXS11364.1 - 0.093 12.6 0.5 0.22 11.4 0.2 1.9 2 0 0 2 2 2 0 F-box-like F-box PF00646.33 KXS11364.1 - 0.16 11.9 0.4 0.37 10.7 0.4 1.7 1 0 0 1 1 1 0 F-box domain DUF4419 PF14388.6 KXS11365.1 - 2e-33 116.2 5.0 2.7e-32 112.4 5.0 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF4419) DUF498 PF04430.14 KXS11366.1 - 1.3e-26 92.8 0.0 3.5e-26 91.4 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) MapZ_EC1 PF18041.1 KXS11368.1 - 0.0013 19.0 0.3 0.008 16.4 0.0 2.2 1 1 1 2 2 2 1 MapZ extracellular domain 1 SH3BP5 PF05276.14 KXS11368.1 - 0.0028 17.5 7.5 0.0038 17.1 7.1 1.4 1 1 0 1 1 1 1 SH3 domain-binding protein 5 (SH3BP5) DUF3540 PF12059.8 KXS11368.1 - 0.011 15.6 1.6 0.017 14.9 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3540) PfUIS3 PF11567.8 KXS11368.1 - 0.012 16.0 0.2 0.2 12.0 0.0 2.2 1 1 1 2 2 2 0 Plasmodium falciparum UIS3 membrane protein AAA_32 PF13654.6 KXS11368.1 - 0.017 13.9 7.1 0.02 13.7 7.1 1.0 1 0 0 1 1 1 0 AAA domain HalX PF08663.10 KXS11368.1 - 0.02 15.2 3.0 0.02 15.2 3.0 3.4 3 1 1 4 4 4 0 HalX domain RICH PF05062.12 KXS11368.1 - 0.023 15.0 7.2 0.024 14.9 1.0 2.7 2 1 0 2 2 2 0 RICH domain FapA PF03961.13 KXS11368.1 - 0.11 11.1 2.4 0.13 10.8 2.4 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A CLZ PF16526.5 KXS11368.1 - 0.27 11.6 13.3 1.5 9.2 5.6 2.9 1 1 3 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ABC_tran_CTD PF16326.5 KXS11368.1 - 0.42 10.9 16.6 0.49 10.7 3.3 3.3 1 1 2 3 3 3 0 ABC transporter C-terminal domain DUF1664 PF07889.12 KXS11368.1 - 1 9.4 6.6 1.9 8.5 0.5 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) Prefoldin_2 PF01920.20 KXS11368.1 - 4.5 7.3 14.6 7.3 6.6 5.4 3.0 2 1 1 3 3 3 0 Prefoldin subunit FlxA PF14282.6 KXS11368.1 - 4.7 7.2 14.2 8.6 6.4 4.9 2.8 1 1 1 2 2 2 0 FlxA-like protein UPF0242 PF06785.11 KXS11368.1 - 5.7 7.0 11.0 8.2 6.5 11.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Trimer_CC PF08954.11 KXS11368.1 - 7.8 6.1 11.5 4.7 6.8 3.3 2.7 2 1 0 2 2 2 0 Trimerisation motif Spc7 PF08317.11 KXS11368.1 - 8.1 5.2 14.8 13 4.6 3.6 1.8 1 1 1 2 2 2 0 Spc7 kinetochore protein HSP20 PF00011.21 KXS11370.1 - 2.1e-17 63.2 0.8 4.2e-15 55.7 0.8 2.1 1 1 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KXS11370.1 - 4.8e-09 35.6 0.0 1.7e-08 33.9 0.0 1.8 1 1 0 1 1 1 1 HSP20-like domain found in ArsA SSP160 PF06933.11 KXS11370.1 - 0.23 9.6 6.0 0.27 9.4 6.0 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Flavi_glycop_C PF02832.16 KXS11370.1 - 0.92 9.7 3.2 2.7 8.2 0.5 2.5 1 1 2 3 3 3 0 Flavivirus glycoprotein, immunoglobulin-like domain adh_short PF00106.25 KXS11371.1 - 7.1e-46 156.1 0.0 9.1e-46 155.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXS11371.1 - 9.5e-28 97.3 0.0 1.2e-27 96.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXS11371.1 - 1.4e-13 51.2 0.0 2.1e-13 50.6 0.0 1.1 1 0 0 1 1 1 1 KR domain WW PF00397.26 KXS11372.1 - 1.3e-12 47.5 0.8 2.5e-12 46.6 0.8 1.5 1 0 0 1 1 1 1 WW domain SMN PF06003.12 KXS11372.1 - 2.3 7.4 5.9 2.8 7.1 5.9 1.2 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Peptidase_C14 PF00656.22 KXS11373.1 - 5.8e-45 154.2 0.0 1.2e-44 153.2 0.0 1.4 1 1 0 1 1 1 1 Caspase domain DUF1072 PF06380.11 KXS11374.1 - 0.25 11.3 0.1 0.25 11.3 0.1 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF1072) ATP-synt_I PF03899.15 KXS11374.1 - 9 6.7 11.6 0.42 11.0 3.3 2.3 2 0 0 2 2 2 0 ATP synthase I chain SH3_9 PF14604.6 KXS11375.1 - 3.4e-34 116.5 5.9 3.9e-13 49.0 0.7 3.5 3 0 0 3 3 3 3 Variant SH3 domain SH3_1 PF00018.28 KXS11375.1 - 1.1e-30 105.0 3.5 5.2e-12 45.2 0.0 4.0 3 1 0 3 3 3 3 SH3 domain SHD1 PF03983.12 KXS11375.1 - 1.3e-26 92.2 0.0 3e-26 91.0 0.0 1.6 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_2 PF07653.17 KXS11375.1 - 1.3e-24 85.6 0.1 1.6e-08 34.1 0.0 3.6 3 0 0 3 3 3 3 Variant SH3 domain SAM_4 PF18017.1 KXS11375.1 - 0.0002 21.3 0.0 0.00035 20.5 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_10 PF17902.1 KXS11375.1 - 0.072 13.2 0.1 36 4.5 0.0 3.3 3 0 0 3 3 3 0 SH3 domain zf-CSL PF05207.13 KXS11376.1 - 0.055 13.2 0.3 0.11 12.2 0.3 1.5 1 1 0 1 1 1 0 CSL zinc finger Hist_deacetyl PF00850.19 KXS11377.1 - 9.2e-57 192.8 0.1 1.2e-56 192.5 0.1 1.1 1 0 0 1 1 1 1 Histone deacetylase domain MFS_1 PF07690.16 KXS11378.1 - 4.9e-16 58.6 39.5 8.6e-14 51.2 34.4 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily QCR10 PF09796.9 KXS11378.1 - 0.58 10.3 0.0 0.58 10.3 0.0 3.6 3 1 1 4 4 4 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) PSP1 PF04468.12 KXS11381.1 - 1.3e-31 108.7 4.7 1.3e-31 108.7 4.7 1.5 2 0 0 2 2 2 1 PSP1 C-terminal conserved region 5TM-5TMR_LYT PF07694.12 KXS11381.1 - 1.4 8.4 2.9 2.2 7.8 2.9 1.2 1 0 0 1 1 1 0 5TMR of 5TMR-LYT PPP4R2 PF09184.11 KXS11382.1 - 1.3e-17 64.4 0.0 1.6e-17 64.0 0.0 1.1 1 0 0 1 1 1 1 PPP4R2 RraA-like PF03737.15 KXS11384.1 - 2.3e-21 76.5 1.6 3.1e-21 76.1 1.6 1.2 1 0 0 1 1 1 1 Aldolase/RraA PRA-PH PF01503.17 KXS11384.1 - 0.12 12.8 0.1 0.68 10.4 0.0 2.1 2 0 0 2 2 2 0 Phosphoribosyl-ATP pyrophosphohydrolase RPN13_C PF16550.5 KXS11384.1 - 0.16 12.2 0.3 8.2 6.7 0.1 2.2 2 0 0 2 2 2 0 UCH-binding domain ubiquitin PF00240.23 KXS11392.1 - 8.1e-27 92.8 0.1 8.7e-27 92.7 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KXS11392.1 - 1.4e-13 50.5 0.0 1.4e-13 50.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KXS11392.1 - 0.0009 19.7 0.0 0.0015 19.0 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 KXS11392.1 - 0.001 19.0 0.0 0.0011 18.9 0.0 1.2 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain DUF2407 PF10302.9 KXS11392.1 - 0.092 13.3 0.0 0.11 13.1 0.0 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain S1FA PF04689.13 KXS11394.1 - 0.0062 16.7 0.0 0.009 16.1 0.0 1.3 1 0 0 1 1 1 1 DNA binding protein S1FA UTP25 PF06862.12 KXS11396.1 - 2.3e-160 534.5 2.1 2.6e-160 534.3 2.1 1.0 1 0 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 DEAD PF00270.29 KXS11396.1 - 0.0041 16.9 0.3 0.12 12.1 0.3 2.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase KH_8 PF17903.1 KXS11397.1 - 2.5e-33 114.0 0.7 4.2e-33 113.3 0.1 1.7 2 0 0 2 2 2 1 Krr1 KH1 domain KH_1 PF00013.29 KXS11397.1 - 0.0031 17.3 0.1 0.0064 16.3 0.1 1.5 1 0 0 1 1 1 1 KH domain KH_4 PF13083.6 KXS11397.1 - 0.046 13.6 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 KH domain GIT_SHD PF08518.11 KXS11398.1 - 1.8e-24 85.1 7.4 2.2e-13 49.6 1.6 2.9 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT FPP PF05911.11 KXS11398.1 - 6.1e-05 21.4 17.8 0.00011 20.6 14.2 2.2 2 0 0 2 2 2 1 Filament-like plant protein, long coiled-coil GIT1_C PF12205.8 KXS11398.1 - 0.00012 22.2 0.5 0.00012 22.2 0.5 3.4 3 1 0 3 3 3 1 G protein-coupled receptor kinase-interacting protein 1 C term ERM PF00769.19 KXS11398.1 - 0.00087 19.2 15.4 0.00087 19.2 15.4 2.9 3 0 0 3 3 3 1 Ezrin/radixin/moesin family DUF3584 PF12128.8 KXS11398.1 - 0.0098 13.5 18.2 0.022 12.3 18.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) BORCS7 PF16088.5 KXS11398.1 - 0.014 15.7 8.5 0.27 11.5 0.1 3.1 2 1 1 3 3 3 0 BLOC-1-related complex sub-unit 7 EzrA PF06160.12 KXS11398.1 - 0.016 13.4 20.1 0.022 13.0 13.4 2.5 2 1 0 3 3 3 0 Septation ring formation regulator, EzrA CSN7a_helixI PF18392.1 KXS11398.1 - 0.055 13.4 0.3 0.15 11.9 0.3 1.7 1 0 0 1 1 1 0 COP9 signalosome complex subunit 7a helix I domain DUF639 PF04842.12 KXS11398.1 - 0.064 12.7 0.2 0.17 11.3 0.0 1.8 2 0 0 2 2 1 0 Plant protein of unknown function (DUF639) TolA_bind_tri PF16331.5 KXS11398.1 - 0.071 13.2 29.9 0.57 10.3 5.6 4.5 3 1 1 4 4 4 0 TolA binding protein trimerisation DUF812 PF05667.11 KXS11398.1 - 0.12 11.2 19.5 0.032 13.1 15.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF812) Spc7 PF08317.11 KXS11398.1 - 0.19 10.6 26.8 0.0088 15.0 10.1 3.2 2 1 1 3 3 3 0 Spc7 kinetochore protein Swi5 PF07061.11 KXS11398.1 - 0.27 11.3 14.7 0.11 12.6 2.4 3.8 2 1 1 3 3 3 0 Swi5 DUF4988 PF16378.5 KXS11398.1 - 0.28 10.8 2.1 0.84 9.3 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function Scaffolding_pro PF11418.8 KXS11398.1 - 0.32 11.6 4.3 3.7 8.2 1.5 2.9 2 0 0 2 2 2 0 Phi29 scaffolding protein DUF4972 PF16342.5 KXS11398.1 - 0.36 10.5 4.3 0.42 10.3 0.1 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF4972) DUF724 PF05266.14 KXS11398.1 - 0.44 10.3 14.9 0.36 10.6 10.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DUF4795 PF16043.5 KXS11398.1 - 0.7 9.5 18.6 5.7 6.5 10.0 3.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4795) BLOC1_2 PF10046.9 KXS11398.1 - 0.85 10.0 14.9 0.13 12.6 0.8 4.1 3 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 bZIP_1 PF00170.21 KXS11398.1 - 0.86 9.7 16.8 3.7 7.7 0.6 4.1 3 1 0 3 3 3 0 bZIP transcription factor COG2 PF06148.11 KXS11398.1 - 1.2 9.2 9.8 0.84 9.7 4.9 3.1 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 PRKG1_interact PF15898.5 KXS11398.1 - 1.5 9.8 26.0 0.64 11.0 9.6 3.5 3 0 0 3 3 2 0 cGMP-dependent protein kinase interacting domain APG6_N PF17675.1 KXS11398.1 - 1.5 9.4 30.0 0.026 15.1 20.3 2.8 3 0 0 3 3 3 0 Apg6 coiled-coil region HSBP1 PF06825.12 KXS11398.1 - 1.7 8.6 6.8 21 5.1 0.3 4.2 2 2 0 2 2 2 0 Heat shock factor binding protein 1 DUF4200 PF13863.6 KXS11398.1 - 2.5 8.5 22.7 0.28 11.6 10.7 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) Tropomyosin_1 PF12718.7 KXS11398.1 - 2.6 8.2 25.4 2.7 8.2 9.8 3.3 2 1 1 3 3 3 0 Tropomyosin like Cob_adeno_trans PF01923.18 KXS11398.1 - 3.9 7.6 13.1 31 4.7 0.0 3.3 2 1 1 3 3 3 0 Cobalamin adenosyltransferase BST2 PF16716.5 KXS11398.1 - 4.1 8.1 20.4 1 10.0 8.0 3.4 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 CENP-F_leu_zip PF10473.9 KXS11398.1 - 4.2 7.4 27.4 4 7.5 0.2 2.9 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3450 PF11932.8 KXS11398.1 - 4.5 6.5 23.8 0.8 9.0 13.0 4.0 2 1 2 4 4 4 0 Protein of unknown function (DUF3450) Laminin_II PF06009.12 KXS11398.1 - 6.3 6.8 20.3 27 4.8 10.7 4.2 2 1 3 5 5 5 0 Laminin Domain II DUF1664 PF07889.12 KXS11398.1 - 7.1 6.7 16.5 7.2 6.7 6.2 4.2 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) ETC_C1_NDUFA4 PF04800.12 KXS11399.1 - 1.2e-36 124.8 0.2 1.4e-36 124.6 0.2 1.0 1 0 0 1 1 1 1 ETC complex I subunit conserved region Pex2_Pex12 PF04757.14 KXS11400.1 - 1.1e-30 107.0 3.2 1.4e-30 106.5 3.2 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region IBN_N PF03810.19 KXS11401.1 - 1.6e-11 44.0 0.2 1.2e-10 41.2 0.0 2.6 3 0 0 3 3 3 1 Importin-beta N-terminal domain Xpo1 PF08389.12 KXS11401.1 - 0.013 15.6 0.0 0.041 13.9 0.0 1.9 1 0 0 1 1 1 0 Exportin 1-like protein HEAT_2 PF13646.6 KXS11401.1 - 0.05 14.0 0.2 10 6.6 0.0 3.5 2 1 0 2 2 2 0 HEAT repeats RNase_H2-Ydr279 PF09468.10 KXS11402.1 - 6.4e-15 55.7 0.2 1.4e-13 51.4 0.2 2.2 1 1 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) wHTH domain Ydr279_N PF17745.1 KXS11402.1 - 0.00015 21.9 0.0 0.00028 21.1 0.0 1.5 1 0 0 1 1 1 1 Ydr279p protein triple barrel domain DOCK_N PF16172.5 KXS11403.1 - 1.4e-44 152.6 0.1 1.3e-27 96.7 0.1 2.5 2 1 1 3 3 3 2 DOCK N-terminus DOCK-C2 PF14429.6 KXS11403.1 - 1e-28 100.5 0.0 1.8e-28 99.7 0.0 1.4 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins SH3_1 PF00018.28 KXS11403.1 - 0.043 13.4 0.0 0.1 12.2 0.0 1.6 1 0 0 1 1 1 0 SH3 domain DHR-2 PF06920.13 KXS11404.1 - 5.9e-67 226.5 1.5 4.8e-66 223.5 1.5 2.1 1 1 0 1 1 1 1 Dock homology region 2 Actin PF00022.19 KXS11405.1 - 5.1e-47 160.4 0.0 5.6e-47 160.2 0.0 1.0 1 0 0 1 1 1 1 Actin FHA PF00498.26 KXS11406.1 - 1.5e-11 44.5 0.0 2.8e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 FHA domain PP1_bind PF15276.6 KXS11406.1 - 2e-10 40.8 2.7 2e-10 40.8 2.7 5.3 5 0 0 5 5 5 1 Protein phosphatase 1 binding COesterase PF00135.28 KXS11407.1 - 4.3e-15 55.6 0.0 4.6e-15 55.5 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXS11407.1 - 0.0014 18.5 0.1 0.003 17.5 0.0 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold FA_desaturase PF00487.24 KXS11408.1 - 1.1e-34 120.4 25.9 1.6e-34 119.9 25.9 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 KXS11408.1 - 8e-10 38.7 0.0 1.9e-09 37.6 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Beta-lactamase PF00144.24 KXS11409.1 - 1.6e-09 37.5 2.6 9.6e-06 25.1 0.4 3.1 1 1 1 2 2 2 2 Beta-lactamase F-box-like PF12937.7 KXS11411.1 - 9e-07 28.7 0.1 3.1e-06 27.0 0.1 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXS11411.1 - 0.015 15.2 0.5 0.099 12.5 0.0 2.5 2 0 0 2 2 2 0 F-box domain AP_endonuc_2 PF01261.24 KXS11411.1 - 0.057 12.9 0.0 0.18 11.2 0.0 1.9 1 1 1 2 2 2 0 Xylose isomerase-like TIM barrel DUF1478 PF07349.11 KXS11411.1 - 0.064 13.1 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1478) F-box_5 PF18511.1 KXS11411.1 - 0.14 11.8 0.0 0.3 10.7 0.0 1.6 1 0 0 1 1 1 0 F-box F-box-like PF12937.7 KXS11412.1 - 2.3e-12 46.6 4.8 4.5e-08 32.9 0.1 3.3 3 0 0 3 3 3 2 F-box-like F-box PF00646.33 KXS11412.1 - 3e-09 36.5 1.2 1.4e-05 24.8 0.0 3.0 3 0 0 3 3 3 2 F-box domain F-box_5 PF18511.1 KXS11412.1 - 0.0049 16.4 0.1 2.4 7.8 0.1 2.5 2 0 0 2 2 2 2 F-box F-box_4 PF15966.5 KXS11412.1 - 0.073 13.0 0.1 0.28 11.1 0.1 2.0 1 0 0 1 1 1 0 F-box TMEM125 PF15109.6 KXS11412.1 - 0.2 12.0 1.2 14 6.0 0.1 3.3 3 0 0 3 3 3 0 TMEM125 protein family F-box-like PF12937.7 KXS11413.1 - 4.2e-06 26.5 0.6 1.1e-05 25.2 0.6 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXS11413.1 - 0.0002 21.1 0.1 0.00064 19.5 0.1 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KXS11414.1 - 1.4e-07 31.3 0.4 5.1e-07 29.5 0.4 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXS11414.1 - 4.2e-05 23.3 0.1 0.00014 21.7 0.1 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KXS11415.1 - 3.8e-05 23.5 0.6 3.8e-05 23.5 0.6 2.2 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 KXS11415.1 - 0.0019 18.0 0.5 0.0075 16.1 0.5 2.1 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KXS11417.1 - 7.5e-06 25.7 0.2 1.5e-05 24.8 0.2 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXS11417.1 - 2.8e-05 23.9 0.2 0.00014 21.7 0.1 2.0 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KXS11421.1 - 2.7e-06 27.1 0.3 6.8e-06 25.9 0.3 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXS11421.1 - 0.00011 22.0 0.1 0.00031 20.5 0.1 1.7 1 0 0 1 1 1 1 F-box domain Med20 PF08612.11 KXS11424.1 - 1.2e-09 37.9 0.0 2.5e-09 36.9 0.0 1.5 1 1 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex MAT1 PF06391.13 KXS11426.1 - 3.9e-15 56.2 3.5 3.9e-15 56.2 3.5 1.3 2 0 0 2 2 2 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_5 PF17121.5 KXS11426.1 - 1.1e-10 41.2 9.1 2.2e-10 40.3 9.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXS11426.1 - 0.00013 21.8 7.6 0.00021 21.2 7.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 KXS11426.1 - 0.00014 22.1 6.5 0.00025 21.3 6.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KXS11426.1 - 0.00051 19.9 5.7 0.0013 18.6 5.7 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KXS11426.1 - 0.00066 19.5 10.2 0.01 15.7 10.2 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KXS11426.1 - 0.0027 17.9 3.0 0.0058 16.9 3.0 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KXS11426.1 - 0.0037 17.1 9.1 0.016 15.0 9.1 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KXS11426.1 - 0.011 15.6 9.3 0.017 15.0 2.8 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 LIM PF00412.22 KXS11426.1 - 0.39 11.0 5.4 0.13 12.5 2.3 1.8 2 0 0 2 2 2 0 LIM domain zf-RING_UBOX PF13445.6 KXS11426.1 - 0.69 10.0 8.1 1.4 9.0 8.1 1.6 1 0 0 1 1 1 0 RING-type zinc-finger MAT1 PF06391.13 KXS11427.1 - 1.5e-09 38.0 3.4 2e-09 37.6 3.4 1.2 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 TPR_2 PF07719.17 KXS11428.1 - 1.9e-21 74.4 6.6 5.9e-06 26.0 0.0 7.6 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_1 PF00515.28 KXS11428.1 - 2.3e-17 62.0 3.5 7.3e-06 25.6 0.0 6.9 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_12 PF13424.6 KXS11428.1 - 5.1e-15 55.5 14.7 1.3e-05 25.3 0.1 6.5 4 2 1 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 KXS11428.1 - 7.6e-13 47.6 2.4 0.00077 19.5 0.0 7.2 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_19 PF14559.6 KXS11428.1 - 8.3e-13 48.6 3.6 9.4e-05 22.8 0.1 5.0 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 KXS11428.1 - 2.6e-10 40.3 12.2 0.012 16.3 0.0 7.7 5 2 3 8 8 7 2 Tetratricopeptide repeat TPR_16 PF13432.6 KXS11428.1 - 1.5e-09 38.3 6.7 8.8e-05 23.1 0.2 4.8 3 2 3 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 KXS11428.1 - 6.5e-09 35.2 6.3 0.21 11.7 0.0 7.1 7 0 0 7 7 7 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KXS11428.1 - 4.4e-08 33.2 1.9 0.088 13.1 0.0 4.3 3 2 1 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 KXS11428.1 - 2.3e-07 30.4 1.2 0.00028 20.5 0.0 3.3 3 0 0 3 3 3 2 TPR repeat TPR_6 PF13174.6 KXS11428.1 - 6.7e-07 29.5 4.2 6.7 7.6 0.0 6.0 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 KXS11428.1 - 8.5e-05 22.7 0.4 7 7.3 0.0 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 KXS11428.1 - 0.0011 19.0 7.4 1.3 9.3 0.2 5.0 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_4 PF07721.14 KXS11428.1 - 0.023 15.3 15.4 4.6 8.2 0.1 6.7 7 0 0 7 7 6 0 Tetratricopeptide repeat NPF PF16601.5 KXS11428.1 - 0.2 12.1 0.8 0.39 11.2 0.8 1.4 1 0 0 1 1 1 0 Rabosyn-5 repeating NPF sequence-motif TPR_MalT PF17874.1 KXS11428.1 - 0.75 9.1 8.1 4.4 6.6 0.0 3.8 3 2 2 5 5 5 0 MalT-like TPR region DUF202 PF02656.15 KXS11430.1 - 2.2 8.8 6.2 0.4 11.1 1.7 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF202) Crp PF00325.20 KXS11431.1 - 0.066 12.9 0.2 0.15 11.8 0.0 1.7 2 0 0 2 2 2 0 Bacterial regulatory proteins, crp family F-box-like PF12937.7 KXS11432.1 - 0.03 14.2 0.2 0.1 12.5 0.2 1.9 1 0 0 1 1 1 0 F-box-like V-SNARE_C PF12352.8 KXS11434.1 - 1.4e-10 41.3 0.2 1.6e-10 41.1 0.2 1.1 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 KXS11434.1 - 5.1e-05 23.1 0.0 6.1e-05 22.9 0.0 1.0 1 0 0 1 1 1 1 Sec20 Sigma70_r4 PF04545.16 KXS11434.1 - 0.033 13.7 0.1 0.056 13.0 0.1 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 Hom_end PF05204.14 KXS11434.1 - 0.14 12.3 0.0 0.14 12.3 0.0 1.2 1 0 0 1 1 1 0 Homing endonuclease Ost4 PF10215.9 KXS11434.1 - 0.36 10.7 2.5 2.4 8.0 0.0 2.3 2 0 0 2 2 2 0 Oligosaccaryltransferase Fungal_trans PF04082.18 KXS11437.1 - 1.9e-08 33.7 0.0 2.2e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3285 PF11688.8 KXS11438.1 - 0.1 12.5 0.1 0.16 11.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3285) peroxidase PF00141.23 KXS11442.1 - 1.1e-32 113.6 0.1 2.3e-18 66.7 0.0 2.3 2 0 0 2 2 2 2 Peroxidase VirB7 PF17413.2 KXS11442.1 - 0.16 11.3 0.2 0.83 9.0 0.1 2.2 2 0 0 2 2 2 0 Outer membrane lipoprotein virB7 DoxX PF07681.12 KXS11442.1 - 0.17 12.5 0.8 60 4.3 0.0 3.5 3 0 0 3 3 3 0 DoxX Macoilin PF09726.9 KXS11443.1 - 0.9 8.0 3.3 1.1 7.7 3.3 1.1 1 0 0 1 1 1 0 Macoilin family DUF4515 PF14988.6 KXS11444.1 - 0.00025 21.0 27.3 0.00025 21.0 27.3 3.2 1 1 2 3 3 3 1 Domain of unknown function (DUF4515) RNR_N PF08343.10 KXS11444.1 - 0.21 11.6 4.5 0.18 11.9 0.7 2.8 2 1 0 2 2 2 0 Ribonucleotide reductase N-terminal Angiomotin_C PF12240.8 KXS11444.1 - 0.5 9.9 37.8 0.25 10.9 22.5 2.7 2 1 0 2 2 2 0 Angiomotin C terminal ApoO PF09769.9 KXS11444.1 - 2 8.4 11.8 6.3 6.8 0.1 4.1 3 1 2 5 5 5 0 Apolipoprotein O STATa_Ig PF18214.1 KXS11444.1 - 4 7.5 7.4 7 6.7 0.7 2.6 2 0 0 2 2 2 0 STATa Immunoglobulin-like domain bZIP_1 PF00170.21 KXS11444.1 - 7.2 6.8 40.2 3.9 7.7 1.4 6.7 4 3 4 8 8 8 0 bZIP transcription factor DUF2203 PF09969.9 KXS11444.1 - 9.9 6.9 34.0 0.33 11.7 6.6 4.5 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2203) Sel1 PF08238.12 KXS11445.1 - 6.2e-25 87.1 9.1 9.3e-06 26.2 0.0 5.7 5 1 0 5 5 5 5 Sel1 repeat LRR_6 PF13516.6 KXS11445.1 - 6.1e-08 32.1 9.2 0.00025 20.8 0.3 4.3 4 0 0 4 4 4 2 Leucine Rich repeat LRR_4 PF12799.7 KXS11445.1 - 8.1e-05 22.9 2.8 0.005 17.2 0.4 2.6 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) TPR_2 PF07719.17 KXS11445.1 - 0.0002 21.2 1.3 7.6 6.9 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 KXS11445.1 - 0.00045 20.7 0.1 1.7 9.2 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat LRR_8 PF13855.6 KXS11445.1 - 0.0013 18.4 4.0 0.012 15.4 3.7 2.6 1 1 0 1 1 1 1 Leucine rich repeat TPR_1 PF00515.28 KXS11445.1 - 0.0017 18.1 1.2 2.3 8.2 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 KXS11445.1 - 0.0021 17.9 1.8 4.4 7.6 0.0 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KXS11445.1 - 0.004 17.3 0.2 0.64 10.3 0.2 3.0 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 KXS11445.1 - 0.017 15.7 0.1 49 4.9 0.0 3.8 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 KXS11445.1 - 0.033 14.5 0.3 6.1 7.2 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 KXS11445.1 - 0.099 12.9 0.1 85 3.8 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat PPR PF01535.20 KXS11445.1 - 0.18 12.1 0.8 5.8 7.4 0.0 3.1 3 0 0 3 3 3 0 PPR repeat Pkinase PF00069.25 KXS11446.1 - 8.2e-17 61.4 0.0 1.8e-14 53.8 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXS11446.1 - 1.1e-12 47.8 0.0 1.1e-10 41.2 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Cytidylate_kin PF02224.18 KXS11447.1 - 2.4e-52 177.8 0.4 5.1e-52 176.7 0.4 1.5 1 1 0 1 1 1 1 Cytidylate kinase AAA_18 PF13238.6 KXS11447.1 - 0.00029 21.4 0.0 0.35 11.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain Cytidylate_kin2 PF13189.6 KXS11447.1 - 0.003 17.7 0.3 0.032 14.3 0.3 2.5 1 1 0 1 1 1 1 Cytidylate kinase-like family TAP42 PF04177.12 KXS11448.1 - 9.6e-71 238.5 0.8 1.1e-70 238.3 0.8 1.0 1 0 0 1 1 1 1 TAP42-like family CENP-C_mid PF15620.6 KXS11448.1 - 0.021 14.8 1.3 0.03 14.3 1.3 1.3 1 0 0 1 1 1 0 Centromere assembly component CENP-C middle DNMT3B-binding region LRR_4 PF12799.7 KXS11450.1 - 0.0022 18.4 0.3 0.0043 17.4 0.1 1.6 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXS11450.1 - 0.018 14.8 0.1 0.061 13.1 0.0 1.9 2 1 0 2 2 2 0 Leucine rich repeat LRR_1 PF00560.33 KXS11450.1 - 0.02 15.4 1.2 0.12 13.0 0.1 2.8 3 1 0 3 3 3 0 Leucine Rich Repeat LRR_6 PF13516.6 KXS11450.1 - 0.067 13.3 0.1 0.14 12.3 0.1 1.6 1 0 0 1 1 1 0 Leucine Rich repeat SH3_9 PF14604.6 KXS11451.1 - 0.00021 21.1 0.0 0.0005 19.9 0.0 1.7 1 1 0 1 1 1 1 Variant SH3 domain LRR_4 PF12799.7 KXS11452.1 - 9.3e-05 22.7 1.0 0.00015 22.0 1.0 1.4 1 0 0 1 1 1 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXS11452.1 - 0.021 14.6 0.5 0.031 14.0 0.5 1.3 1 0 0 1 1 1 0 Leucine rich repeat DUF167 PF02594.16 KXS11454.1 - 9.4e-21 73.7 0.0 1.1e-20 73.5 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised ACR, YggU family COG1872 XPG_I_2 PF12813.7 KXS11455.1 - 7.9e-07 28.8 0.1 1.2e-06 28.2 0.1 1.2 1 0 0 1 1 1 1 XPG domain containing XPG_I PF00867.18 KXS11455.1 - 0.012 15.9 0.0 0.023 15.1 0.0 1.5 1 0 0 1 1 1 0 XPG I-region Pheromone PF08015.11 KXS11455.1 - 2 9.5 6.5 2.6 9.1 2.3 2.8 2 0 0 2 2 2 0 Fungal mating-type pheromone SH2_2 PF14633.6 KXS11457.1 - 3.2e-37 128.0 0.9 8.3e-37 126.7 0.2 2.0 2 0 0 2 2 2 1 SH2 domain HHH_7 PF14635.6 KXS11457.1 - 1.3e-19 70.4 0.0 2.7e-19 69.4 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.6 KXS11457.1 - 1.6e-19 70.2 0.0 4.2e-19 68.8 0.0 1.7 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 HTH_44 PF14641.6 KXS11457.1 - 1.2e-10 41.9 0.1 3.4e-10 40.4 0.1 1.7 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 SPT6_acidic PF14632.6 KXS11457.1 - 3.6e-08 33.9 21.3 3.6e-08 33.9 21.3 7.1 7 2 0 7 7 7 2 Acidic N-terminal SPT6 HHH_9 PF17674.1 KXS11457.1 - 0.00033 21.5 1.9 0.00094 20.0 0.5 2.6 2 0 0 2 2 2 1 HHH domain Tex_N PF09371.10 KXS11457.1 - 0.00037 20.2 0.1 0.03 14.0 0.1 2.6 1 1 0 1 1 1 1 Tex-like protein N-terminal domain Forkhead PF00250.18 KXS11458.1 - 4.3e-31 107.0 0.1 4.7e-31 106.9 0.1 1.0 1 0 0 1 1 1 1 Forkhead domain HSP70 PF00012.20 KXS11459.1 - 1.7e-64 218.1 0.5 3.5e-51 174.1 0.1 3.6 1 1 1 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 KXS11459.1 - 7.9e-05 21.6 3.1 0.00028 19.8 0.5 2.6 3 0 0 3 3 3 1 MreB/Mbl protein FAM183 PF14886.6 KXS11460.1 - 0.029 15.1 0.9 0.066 13.9 0.0 2.0 2 1 0 2 2 2 0 FAM183A and FAM183B related Barttin PF15462.6 KXS11460.1 - 0.51 10.1 4.5 0.84 9.4 4.5 1.4 1 0 0 1 1 1 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) Cactin_mid PF10312.9 KXS11461.1 - 7.9e-60 202.0 0.7 7.9e-60 202.0 0.7 3.1 4 0 0 4 4 4 1 Conserved mid region of cactin CactinC_cactus PF09732.9 KXS11461.1 - 8.3e-60 200.2 9.9 1.6e-59 199.3 9.9 1.5 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein SF3A2 PF16835.5 KXS11461.1 - 0.072 13.5 0.1 0.33 11.4 0.1 2.1 1 0 0 1 1 1 0 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) CCCAP PF15964.5 KXS11462.1 - 0.00064 18.2 1.3 0.001 17.4 1.3 1.3 1 0 0 1 1 1 1 Centrosomal colon cancer autoantigen protein family Goodbye PF17109.5 KXS11462.1 - 0.0028 18.1 0.1 0.0073 16.8 0.1 1.6 1 0 0 1 1 1 1 fungal STAND N-terminal Goodbye domain GAS PF13851.6 KXS11462.1 - 0.018 14.4 2.5 0.028 13.8 2.5 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding BRE1 PF08647.11 KXS11462.1 - 0.037 14.1 3.2 0.063 13.4 3.2 1.4 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase DUF1722 PF08349.11 KXS11462.1 - 0.11 12.7 0.0 0.52 10.6 0.0 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1722) IFT20 PF14931.6 KXS11462.1 - 0.12 12.5 3.2 0.93 9.7 2.1 2.3 2 0 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 Folliculin PF11704.8 KXS11462.1 - 0.14 12.0 0.1 0.14 12.0 0.1 1.7 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport Occludin_ELL PF07303.13 KXS11462.1 - 0.15 12.8 1.7 0.43 11.3 0.7 2.1 2 0 0 2 2 2 0 Occludin homology domain DUF641 PF04859.12 KXS11462.1 - 0.16 12.3 1.9 0.31 11.4 1.2 1.8 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) Vps51 PF08700.11 KXS11462.1 - 0.2 11.7 1.6 0.52 10.4 1.0 1.9 1 1 0 1 1 1 0 Vps51/Vps67 DUF737 PF05300.11 KXS11462.1 - 1.2 9.4 6.4 0.57 10.5 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF737) AAA PF00004.29 KXS11464.1 - 1.2e-41 142.3 0.0 2.9e-41 141.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KXS11464.1 - 1e-16 60.6 0.1 2.2e-16 59.6 0.1 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 KXS11464.1 - 7.7e-11 41.6 0.1 2.3e-10 40.1 0.1 1.9 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 KXS11464.1 - 8.5e-06 25.8 0.4 4.4e-05 23.5 0.1 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KXS11464.1 - 1.9e-05 25.1 0.3 0.0074 16.7 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_2 PF07724.14 KXS11464.1 - 0.00015 21.9 0.3 0.00075 19.7 0.0 2.2 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 KXS11464.1 - 0.00017 21.4 0.0 0.00049 19.9 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KXS11464.1 - 0.00079 19.7 0.4 0.061 13.6 0.4 2.5 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 KXS11464.1 - 0.0046 16.4 0.1 0.047 13.2 0.0 2.2 2 0 0 2 2 2 1 PhoH-like protein AAA_33 PF13671.6 KXS11464.1 - 0.0051 17.0 0.1 0.023 14.8 0.1 2.3 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 KXS11464.1 - 0.0066 15.6 0.0 0.018 14.2 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF815) Mg_chelatase PF01078.21 KXS11464.1 - 0.013 14.9 0.1 0.034 13.5 0.1 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF1192 PF06698.11 KXS11464.1 - 0.019 15.0 0.9 0.058 13.5 0.9 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) IstB_IS21 PF01695.17 KXS11464.1 - 0.025 14.3 0.0 0.051 13.3 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein Atg14 PF10186.9 KXS11464.1 - 0.025 13.7 1.0 0.038 13.1 1.0 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 AAA_11 PF13086.6 KXS11464.1 - 0.026 14.3 2.3 0.25 11.1 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KXS11464.1 - 0.03 14.1 0.8 0.17 11.6 0.1 2.5 2 1 0 2 2 2 0 AAA domain AAA_3 PF07726.11 KXS11464.1 - 0.031 14.1 0.2 1.3 8.8 0.0 2.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) TRAF_BIRC3_bd PF16673.5 KXS11464.1 - 0.066 13.0 3.5 0.16 11.7 2.0 2.3 2 0 0 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain FlxA PF14282.6 KXS11464.1 - 0.081 12.9 1.1 0.25 11.3 0.5 2.1 2 0 0 2 2 2 0 FlxA-like protein AAA_18 PF13238.6 KXS11464.1 - 0.11 13.0 0.2 0.7 10.4 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KXS11464.1 - 0.13 11.8 0.0 0.28 10.7 0.0 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region Cdh1_DBD_1 PF18196.1 KXS11464.1 - 1.1 9.6 6.4 20 5.5 0.0 3.1 2 1 1 3 3 3 0 Chromodomain helicase DNA-binding domain 1 Peptidase_M14 PF00246.24 KXS11465.1 - 5.4e-70 236.5 0.1 6.5e-70 236.2 0.1 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Peptidase_M14 PF00246.24 KXS11466.1 - 6.9e-72 242.7 0.1 9.4e-72 242.2 0.1 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase TMEM223 PF14640.6 KXS11467.1 - 2.6e-15 57.0 0.0 4.2e-15 56.3 0.0 1.2 1 0 0 1 1 1 1 Transmembrane protein 223 GST_N_3 PF13417.6 KXS11468.1 - 8.2e-11 42.2 0.0 1.6e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KXS11468.1 - 8e-08 32.4 0.0 1.7e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KXS11468.1 - 9.7e-07 29.0 0.0 1.9e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KXS11468.1 - 2.3e-06 27.5 0.1 4.2e-06 26.7 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KXS11468.1 - 0.00024 21.4 0.0 0.00056 20.2 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 KXS11468.1 - 0.061 14.1 0.0 1.3 9.8 0.0 2.4 2 0 0 2 2 2 0 Glutathione S-transferase N-terminal domain GST_C_3 PF14497.6 KXS11468.1 - 0.065 13.4 0.1 0.12 12.6 0.1 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain COX5B PF01215.19 KXS11469.1 - 3.6e-26 91.4 0.0 4.7e-26 91.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb Transcrip_reg PF01709.20 KXS11471.1 - 1.2e-63 214.8 0.0 1.3e-63 214.6 0.0 1.0 1 0 0 1 1 1 1 Transcriptional regulator HSP90 PF00183.18 KXS11474.1 - 1.8e-173 578.2 14.8 1.8e-173 578.2 14.8 1.3 2 0 0 2 2 2 1 Hsp90 protein HATPase_c PF02518.26 KXS11474.1 - 3.7e-11 43.5 0.1 8.8e-11 42.3 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KXS11474.1 - 3e-09 36.8 0.3 8.3e-09 35.4 0.3 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF4368 PF14287.6 KXS11474.1 - 0.085 13.2 0.0 0.38 11.1 0.0 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4368) WD40 PF00400.32 KXS11475.1 - 7.5e-45 150.0 18.8 1.6e-05 25.6 1.9 11.4 11 0 0 11 11 11 10 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXS11475.1 - 9e-19 67.6 0.3 0.0036 17.6 0.1 6.7 3 2 3 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KXS11475.1 - 2.2e-08 34.2 0.1 0.39 10.6 0.1 4.8 2 2 3 5 5 5 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KXS11475.1 - 0.00011 21.3 5.0 3.3 6.6 1.0 5.7 3 2 2 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KXS11475.1 - 0.00072 18.3 0.1 0.41 9.2 0.1 2.9 3 0 0 3 3 3 2 Nucleoporin Nup120/160 PD40 PF07676.12 KXS11475.1 - 0.0021 17.9 0.2 62 3.7 0.0 4.8 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Lactonase PF10282.9 KXS11475.1 - 0.03 13.6 0.4 0.35 10.1 0.0 2.5 2 0 0 2 2 2 0 Lactonase, 7-bladed beta-propeller TFIIIC_delta PF12657.7 KXS11475.1 - 0.036 14.0 1.7 2.5 8.0 0.2 3.5 2 2 1 3 3 3 0 Transcription factor IIIC subunit delta N-term IKI3 PF04762.12 KXS11475.1 - 0.073 11.1 0.0 3.5 5.5 0.0 2.3 2 0 0 2 2 2 0 IKI3 family WD40_like PF17005.5 KXS11475.1 - 0.097 12.0 0.0 13 5.0 0.0 3.3 3 0 0 3 3 3 0 WD40-like domain DOMON PF03351.17 KXS11476.1 - 2.2e-16 60.2 0.0 4.2e-16 59.3 0.0 1.4 1 0 0 1 1 1 1 DOMON domain CDH-cyt PF16010.5 KXS11476.1 - 1.1e-11 44.7 0.2 1.8e-11 44.1 0.2 1.2 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase Cytochrom_B561 PF03188.16 KXS11476.1 - 1.3e-10 41.5 12.5 2.6e-10 40.5 12.5 1.5 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 MARVEL PF01284.23 KXS11476.1 - 0.00035 20.6 2.8 0.00035 20.6 2.8 3.0 3 1 0 3 3 3 1 Membrane-associating domain DUF4079 PF13301.6 KXS11476.1 - 0.41 10.8 13.4 0.5 10.5 11.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4079) Abhydrolase_9_N PF15420.6 KXS11476.1 - 0.62 10.0 8.5 1.2 9.1 8.5 1.5 1 0 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus Bax1-I PF01027.20 KXS11476.1 - 0.99 9.2 19.8 0.033 14.0 13.6 1.6 2 0 0 2 2 2 0 Inhibitor of apoptosis-promoting Bax1 DUF2427 PF10348.9 KXS11476.1 - 1.9 8.3 16.8 0.061 13.1 9.0 2.6 2 2 0 2 2 2 0 Domain of unknown function (DUF2427) Cation_ATPase_C PF00689.21 KXS11476.1 - 3.2 7.4 14.5 2.1 8.0 11.9 1.9 1 1 0 1 1 1 0 Cation transporting ATPase, C-terminus tRNA-synt_2d PF01409.20 KXS11477.1 - 1.9e-91 305.9 0.0 2.4e-91 305.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 KXS11477.1 - 5.1e-19 68.3 1.1 2.7e-18 66.0 0.4 2.5 2 0 0 2 2 2 1 PheRS DNA binding domain 3 tRNA_synthFbeta PF17759.1 KXS11477.1 - 3.8e-08 33.0 0.0 0.00013 21.5 0.0 2.3 2 0 0 2 2 2 2 Phenylalanyl tRNA synthetase beta chain CLM domain tRNA-synt_2b PF00587.25 KXS11477.1 - 4.8e-05 23.4 0.0 0.00012 22.2 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2 PF00152.20 KXS11477.1 - 0.002 17.3 0.1 0.015 14.4 0.0 2.2 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) PheRS_DBD2 PF18554.1 KXS11477.1 - 0.002 18.1 3.7 0.0043 17.0 3.7 1.6 1 0 0 1 1 1 1 PheRS DNA binding domain 2 ING PF12998.7 KXS11478.1 - 6.1e-18 65.3 0.1 1.2e-17 64.3 0.1 1.4 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 KXS11478.1 - 1.1e-06 28.4 6.0 1.8e-06 27.7 6.0 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KXS11478.1 - 0.56 9.8 3.4 1.1 8.8 3.4 1.5 1 0 0 1 1 1 0 PHD-finger LNS2 PF08235.13 KXS11479.1 - 3.6e-98 327.6 0.0 5.6e-98 326.9 0.0 1.3 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 KXS11479.1 - 4.7e-37 126.0 0.0 8.2e-37 125.3 0.0 1.4 1 0 0 1 1 1 1 lipin, N-terminal conserved region Lipin_mid PF16876.5 KXS11479.1 - 8.8e-22 77.2 0.0 1.5e-21 76.4 0.0 1.4 1 0 0 1 1 1 1 Lipin/Ned1/Smp2 multi-domain protein middle domain Actin PF00022.19 KXS11480.1 - 4.9e-113 377.8 0.0 2.1e-112 375.7 0.0 1.7 1 1 0 1 1 1 1 Actin GerD PF17898.1 KXS11480.1 - 0.063 13.2 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 Spore germination GerD central core domain Ion_trans PF00520.31 KXS11481.1 - 0.0014 17.9 5.7 0.0014 17.9 5.7 2.2 2 0 0 2 2 2 1 Ion transport protein PKD_channel PF08016.12 KXS11481.1 - 0.0086 14.8 2.4 0.015 14.0 2.4 1.4 1 0 0 1 1 1 1 Polycystin cation channel FtsX PF02687.21 KXS11484.1 - 0.19 12.2 8.5 0.19 12.2 0.9 2.1 1 1 1 2 2 2 0 FtsX-like permease family Ferric_reduct PF01794.19 KXS11487.1 - 4.4e-19 68.8 11.6 4.4e-19 68.8 11.6 1.9 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KXS11487.1 - 3.6e-17 62.9 0.0 8.5e-17 61.7 0.0 1.6 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KXS11487.1 - 2e-15 56.8 0.0 3.6e-15 56.0 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 KXS11487.1 - 1.9e-06 28.5 0.0 1.1e-05 26.1 0.0 2.1 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain PAC3 PF10178.9 KXS11488.1 - 2.1e-08 34.2 0.0 1.2e-06 28.5 0.0 2.3 2 0 0 2 2 2 2 Proteasome assembly chaperone 3 XAP5 PF04921.14 KXS11489.1 - 2.9e-83 279.5 1.8 3.9e-83 279.1 1.8 1.1 1 0 0 1 1 1 1 XAP5, circadian clock regulator HLH PF00010.26 KXS11490.1 - 7e-13 48.3 0.0 2.1e-12 46.8 0.0 1.9 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Il13Ra_Ig PF18001.1 KXS11491.1 - 0.29 11.3 5.1 0.22 11.7 0.7 3.0 2 1 1 3 3 3 0 Interleukin-13 receptor subunit alpha Ig-like domain TPH PF13868.6 KXS11491.1 - 1.7 7.0 117.4 0.0031 16.1 90.9 2.2 1 1 1 2 2 2 0 Trichohyalin-plectin-homology domain Fungal_trans PF04082.18 KXS11492.1 - 0.00013 21.1 0.1 0.00026 20.1 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Erg28 PF03694.13 KXS11494.1 - 9.9e-29 99.9 3.2 1.2e-28 99.7 3.2 1.1 1 0 0 1 1 1 1 Erg28 like protein DUF2381 PF09544.10 KXS11495.1 - 0.027 14.0 4.5 0.033 13.7 4.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2381) Hamartin PF04388.12 KXS11496.1 - 9.4 4.8 9.4 11 4.5 9.4 1.0 1 0 0 1 1 1 0 Hamartin protein Dimer_Tnp_hAT PF05699.14 KXS11497.1 - 6.8e-06 25.8 0.0 1.7e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4413 PF14372.6 KXS11497.1 - 0.0017 18.7 1.4 0.012 16.0 0.3 2.5 1 1 1 2 2 2 1 Domain of unknown function (DUF4413) UNC-93 PF05978.16 KXS11498.1 - 0.0023 17.7 0.7 0.24 11.1 0.0 2.4 2 0 0 2 2 2 2 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 KXS11498.1 - 9.5 5.0 33.8 4.7 6.0 28.7 2.5 1 1 0 1 1 1 0 Major Facilitator Superfamily zf-MYND PF01753.18 KXS11499.1 - 1e-10 41.5 1.9 1.6e-10 40.9 1.9 1.4 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KXS11499.1 - 0.057 13.7 0.5 0.089 13.1 0.5 1.4 1 1 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 KXS11500.1 - 9.5e-11 41.6 4.5 2.8e-10 40.1 4.5 1.9 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KXS11500.1 - 0.19 12.1 3.1 0.19 12.1 0.4 2.2 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding adh_short_C2 PF13561.6 KXS11502.1 - 7.1e-57 192.6 0.0 9.7e-57 192.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXS11502.1 - 9.3e-47 159.0 0.0 1.2e-46 158.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXS11502.1 - 6.1e-11 42.6 0.0 1e-10 41.8 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXS11502.1 - 5e-05 22.9 0.0 7.5e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXS11502.1 - 0.039 13.4 0.0 0.06 12.7 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Eno-Rase_NADH_b PF12242.8 KXS11502.1 - 0.27 11.0 0.9 0.93 9.3 0.8 2.0 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF3482 PF11981.8 KXS11503.1 - 0.24 10.8 0.0 0.25 10.7 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) ADK PF00406.22 KXS11504.1 - 4.8e-41 140.4 0.0 6.3e-41 140.0 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KXS11504.1 - 6.8e-35 120.4 0.0 9.4e-35 120.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KXS11504.1 - 8.2e-09 36.1 0.0 1.3e-08 35.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KXS11504.1 - 4.6e-06 26.8 0.1 1.5e-05 25.2 0.1 1.8 1 1 0 1 1 1 1 AAA domain MFS_1 PF07690.16 KXS11505.1 - 9.1e-30 103.8 34.8 9.1e-30 103.8 34.8 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KXS11505.1 - 5.3e-06 26.0 3.0 5.3e-06 26.0 3.0 2.7 2 1 1 3 3 3 1 Uncharacterised MFS-type transporter YbfB SNARE_assoc PF09335.11 KXS11506.1 - 2.7e-05 24.7 0.1 2.7e-05 24.7 0.1 2.7 3 0 0 3 3 3 1 SNARE associated Golgi protein Mg_trans_NIPA PF05653.14 KXS11507.1 - 1.6e-87 293.3 19.1 6.7e-87 291.3 19.1 1.7 1 1 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 KXS11507.1 - 0.00026 21.2 6.8 0.00026 21.2 6.8 4.7 3 1 1 4 4 4 2 EamA-like transporter family Saf_2TM PF18303.1 KXS11507.1 - 0.52 9.9 4.8 0.32 10.6 1.1 2.5 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain PRELI PF04707.14 KXS11508.1 - 1.2e-41 142.2 0.1 5.4e-41 140.0 0.1 1.8 1 1 0 1 1 1 1 PRELI-like family DUF746 PF05344.11 KXS11510.1 - 0.082 12.8 0.1 0.3 10.9 0.0 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF746) tRNA-synt_1d PF00750.19 KXS11511.1 - 8e-114 380.2 0.0 6.5e-113 377.2 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 KXS11511.1 - 2.1e-29 102.1 0.1 5.5e-29 100.8 0.1 1.8 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 KXS11511.1 - 2.3e-07 31.3 0.0 5.4e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain tRNA-synt_1e PF01406.19 KXS11511.1 - 0.014 14.7 0.0 0.025 13.9 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain GST_C_2 PF13410.6 KXS11511.1 - 0.028 14.4 0.0 0.079 13.0 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain HAP1_N PF04849.13 KXS11512.1 - 0.04 13.1 1.2 0.067 12.4 1.2 1.2 1 0 0 1 1 1 0 HAP1 N-terminal conserved region ZapB PF06005.12 KXS11512.1 - 0.066 13.7 3.3 0.075 13.5 0.7 2.2 2 0 0 2 2 2 0 Cell division protein ZapB TMEM247 PF15444.6 KXS11512.1 - 0.18 11.8 0.3 0.3 11.1 0.3 1.3 1 0 0 1 1 1 0 Transmembrane protein 247 zf-C3HC4_3 PF13920.6 KXS11513.1 - 6.8e-14 51.5 10.3 6.8e-14 51.5 10.3 2.9 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.21 KXS11513.1 - 5e-12 45.8 6.5 5e-12 45.8 6.5 2.7 2 1 0 2 2 1 1 FYVE zinc finger zf-RING_2 PF13639.6 KXS11513.1 - 2.6e-05 24.4 10.3 2.6e-05 24.4 10.3 2.7 2 1 0 2 2 2 1 Ring finger domain Armet PF10208.9 KXS11513.1 - 0.00028 20.8 0.0 0.015 15.3 0.0 2.5 2 0 0 2 2 2 1 Degradation arginine-rich protein for mis-folding zf-C3HC4 PF00097.25 KXS11513.1 - 0.00034 20.4 12.4 0.00034 20.4 12.4 3.1 2 1 1 3 3 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KXS11513.1 - 0.00078 19.3 10.2 0.00078 19.3 10.2 2.9 2 1 1 3 3 3 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 KXS11513.1 - 0.0011 18.8 11.6 0.0011 18.8 11.6 3.0 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXS11513.1 - 0.0014 18.5 11.5 0.0014 18.5 11.5 2.9 2 1 0 2 2 2 1 zinc-RING finger domain FYVE_2 PF02318.16 KXS11513.1 - 0.0023 18.1 4.2 0.0023 18.1 4.2 2.5 2 0 0 2 2 2 1 FYVE-type zinc finger SAP PF02037.27 KXS11513.1 - 0.024 14.4 0.6 1 9.2 0.0 2.7 2 1 0 2 2 2 0 SAP domain Pellino PF04710.14 KXS11513.1 - 0.032 12.9 0.2 0.049 12.3 0.2 1.3 1 0 0 1 1 1 0 Pellino Ish1 PF10281.9 KXS11513.1 - 0.059 13.7 0.0 0.14 12.5 0.0 1.6 1 0 0 1 1 1 0 Putative stress-responsive nuclear envelope protein zf-C3HC4_4 PF15227.6 KXS11513.1 - 5.3 7.3 26.0 0.12 12.5 7.7 3.8 2 2 2 4 4 4 0 zinc finger of C3HC4-type, RING Glyco_transf_28 PF03033.20 KXS11514.1 - 1.7e-13 50.8 0.0 4.8e-13 49.4 0.0 1.8 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain FaeA PF04703.12 KXS11514.1 - 0.12 12.8 0.1 0.27 11.7 0.1 1.6 1 0 0 1 1 1 0 FaeA-like protein HEAT_EZ PF13513.6 KXS11514.1 - 0.17 12.4 0.7 66 4.2 0.1 3.8 3 0 0 3 3 3 0 HEAT-like repeat HEAT PF02985.22 KXS11514.1 - 0.31 11.4 2.3 41 4.8 0.0 4.1 4 0 0 4 4 4 0 HEAT repeat PH PF00169.29 KXS11516.1 - 2.4e-08 34.4 0.0 4.1e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 KXS11516.1 - 0.015 15.7 0.6 0.19 12.1 0.1 2.6 2 1 0 2 2 2 0 Pleckstrin homology domain FAD_binding_1 PF00667.20 KXS11518.1 - 0.15 11.6 0.0 4 6.9 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain MFS_1 PF07690.16 KXS11519.1 - 1.1e-24 87.1 62.1 4e-24 85.2 54.9 2.8 1 1 2 3 3 3 2 Major Facilitator Superfamily KTI12 PF08433.10 KXS11520.1 - 1.8e-05 24.3 0.0 0.02 14.3 0.0 3.1 2 1 1 3 3 3 1 Chromatin associated protein KTI12 AAA PF00004.29 KXS11520.1 - 0.0008 19.8 0.0 0.0034 17.8 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KXS11520.1 - 0.0011 19.5 0.0 0.0021 18.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KXS11520.1 - 0.0014 18.8 0.1 0.49 10.5 0.0 2.5 2 1 0 2 2 2 1 AAA domain TsaE PF02367.17 KXS11520.1 - 0.0052 16.8 0.0 0.0097 15.9 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 KXS11520.1 - 0.007 16.6 0.3 0.025 14.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KXS11520.1 - 0.008 16.6 0.4 0.014 15.8 0.4 1.8 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 KXS11520.1 - 0.026 14.3 0.0 0.059 13.1 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain ABC_tran PF00005.27 KXS11520.1 - 0.042 14.4 0.0 0.1 13.1 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 KXS11520.1 - 0.054 13.8 0.4 0.41 10.9 0.0 2.2 2 1 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KXS11520.1 - 0.071 13.2 0.0 0.19 11.8 0.0 1.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_17 PF13207.6 KXS11520.1 - 0.075 13.5 0.0 0.31 11.4 0.0 2.1 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 KXS11520.1 - 0.1 12.2 0.1 0.36 10.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KXS11520.1 - 0.12 12.1 0.0 0.39 10.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KXS11520.1 - 0.13 11.6 0.0 0.23 10.7 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin NB-ARC PF00931.22 KXS11520.1 - 0.17 11.0 0.0 0.31 10.2 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain MOZART1 PF12554.8 KXS11521.1 - 3.4e-23 81.2 0.2 4.2e-23 80.9 0.2 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated LRR_4 PF12799.7 KXS11522.1 - 0.0069 16.8 4.3 0.045 14.2 4.1 2.1 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXS11522.1 - 0.01 15.6 0.9 0.017 14.8 0.9 1.3 1 0 0 1 1 1 0 Leucine rich repeat RabGAP-TBC PF00566.18 KXS11523.1 - 7.3e-47 159.8 0.0 5.6e-46 156.9 0.0 2.0 2 0 0 2 2 2 1 Rab-GTPase-TBC domain SPDY PF03771.16 KXS11526.1 - 3.4 7.7 5.1 28 4.7 0.0 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF317) SesA PF17107.5 KXS11527.1 - 0.01 16.0 0.0 0.028 14.6 0.0 1.7 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases FAD-oxidase_C PF02913.19 KXS11529.1 - 1.9e-38 132.5 0.0 2.7e-38 132.0 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KXS11529.1 - 1.7e-30 105.6 0.7 3.5e-30 104.6 0.5 1.6 2 0 0 2 2 2 1 FAD binding domain NAD_binding_10 PF13460.6 KXS11531.1 - 5.4e-05 23.1 0.0 6.3e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 KXS11531.1 - 0.016 15.6 0.1 0.034 14.6 0.1 1.5 1 1 1 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain DUF3768 PF12599.8 KXS11531.1 - 0.12 12.4 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3768) JTB PF05439.12 KXS11532.1 - 0.0059 16.6 1.1 0.023 14.8 0.5 2.0 2 0 0 2 2 2 1 Jumping translocation breakpoint protein (JTB) DUF3357 PF11837.8 KXS11532.1 - 0.069 13.6 0.0 0.15 12.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) Fungus-induced PF10917.8 KXS11532.1 - 0.35 11.2 3.5 3.2 8.1 0.5 2.7 2 0 0 2 2 2 0 Fungus-induced protein Linker_histone PF00538.19 KXS11534.1 - 4.6e-27 94.2 1.1 6.5e-27 93.7 0.1 1.8 2 0 0 2 2 2 1 linker histone H1 and H5 family DUF4724 PF15852.5 KXS11534.1 - 1.8 9.1 4.4 2.9 8.4 0.0 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4724) SH3_1 PF00018.28 KXS11535.1 - 1.3e-07 31.1 0.0 2.1e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KXS11535.1 - 3.4e-06 26.8 0.0 5.3e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KXS11536.1 - 8.3e-06 25.6 0.0 1.7e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXS11536.1 - 0.00018 21.1 0.0 0.00035 20.1 0.0 1.5 1 0 0 1 1 1 1 SH3 domain LPMO_10 PF03067.15 KXS11537.1 - 0.0013 19.4 0.0 0.0017 19.1 0.0 1.1 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading SH3_9 PF14604.6 KXS11539.1 - 0.00012 21.8 0.0 0.0002 21.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXS11539.1 - 0.0025 17.4 0.0 0.004 16.7 0.0 1.3 1 0 0 1 1 1 1 SH3 domain Podoplanin PF05808.11 KXS11539.1 - 0.015 15.4 2.3 0.046 13.8 2.3 1.8 1 0 0 1 1 1 0 Podoplanin SH3_9 PF14604.6 KXS11540.1 - 3.8e-05 23.4 0.0 6.3e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXS11540.1 - 0.0044 16.6 0.0 0.0073 15.9 0.0 1.4 1 0 0 1 1 1 1 SH3 domain EphA2_TM PF14575.6 KXS11540.1 - 0.018 15.9 0.1 0.049 14.5 0.0 1.8 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Amnionless PF14828.6 KXS11540.1 - 0.13 11.1 0.9 0.23 10.2 0.0 1.8 2 0 0 2 2 2 0 Amnionless SH3_9 PF14604.6 KXS11542.1 - 0.00026 20.8 0.0 0.00049 19.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXS11542.1 - 0.017 14.7 0.0 0.028 14.0 0.0 1.4 1 0 0 1 1 1 0 SH3 domain EphA2_TM PF14575.6 KXS11542.1 - 0.099 13.5 0.2 0.25 12.2 0.0 1.7 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF3827 PF12877.7 KXS11542.1 - 3 6.1 10.1 0.45 8.8 5.7 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3827) RRM_1 PF00076.22 KXS11543.1 - 1.4e-26 92.0 0.0 1.3e-10 40.9 0.0 5.8 6 0 0 6 6 6 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SPOC PF07744.13 KXS11543.1 - 3.8e-07 30.1 0.0 7.8e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 SPOC domain RRM_3 PF08777.11 KXS11543.1 - 2e-05 24.6 0.1 0.21 11.7 0.1 2.6 2 0 0 2 2 2 2 RNA binding motif BRAP2 PF07576.12 KXS11543.1 - 2.1e-05 24.6 0.0 0.033 14.4 0.0 2.4 2 0 0 2 2 2 2 BRCA1-associated protein 2 RRM_7 PF16367.5 KXS11543.1 - 0.00016 21.7 0.3 5.8 7.1 0.0 4.6 5 0 0 5 5 5 2 RNA recognition motif RRM_5 PF13893.6 KXS11543.1 - 0.023 14.3 0.0 0.054 13.1 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SET_assoc PF11767.8 KXS11543.1 - 0.064 12.9 0.0 5 6.9 0.0 2.8 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated LysM PF01476.20 KXS11544.1 - 4.8e-09 36.1 0.0 7.7e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 LysM domain Ribosomal_L30_N PF08079.12 KXS11545.1 - 1.2e-27 96.0 15.8 2.4e-27 95.0 15.8 1.5 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 KXS11545.1 - 6.8e-19 67.5 1.1 1.7e-18 66.2 1.1 1.8 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Endonuclease_NS PF01223.23 KXS11547.1 - 0.017 14.9 0.0 0.062 13.1 0.0 1.8 1 1 0 1 1 1 0 DNA/RNA non-specific endonuclease Bromodomain PF00439.25 KXS11548.1 - 2e-16 59.8 0.0 3.4e-16 59.1 0.0 1.4 1 0 0 1 1 1 1 Bromodomain GATA PF00320.27 KXS11548.1 - 1.5e-05 24.5 1.2 1.5e-05 24.5 1.2 2.0 2 0 0 2 2 2 1 GATA zinc finger TFIIE-A_C PF11521.8 KXS11548.1 - 8.7 6.7 8.8 1.5 9.2 0.2 3.0 3 0 0 3 3 3 0 C-terminal general transcription factor TFIIE alpha Pkinase PF00069.25 KXS11549.1 - 3.1e-36 125.1 0.0 4.1e-36 124.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS11549.1 - 6.8e-14 51.8 0.0 7.7e-14 51.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXS11549.1 - 0.0032 17.4 0.0 0.0055 16.7 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXS11549.1 - 0.0066 15.3 0.0 0.0086 14.9 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KXS11549.1 - 0.033 13.5 0.0 0.044 13.1 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 KXS11549.1 - 0.039 13.3 0.0 0.056 12.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KXS11550.1 - 1.5e-56 191.7 0.0 1.8e-56 191.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS11550.1 - 9.9e-26 90.6 0.0 1.4e-25 90.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KXS11550.1 - 0.00016 21.1 0.0 0.0003 20.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXS11550.1 - 0.00045 20.2 0.0 0.00081 19.4 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXS11550.1 - 0.0033 16.2 0.0 0.0051 15.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KXS11550.1 - 0.0089 15.4 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like ALG3 PF05208.13 KXS11551.1 - 2.9e-133 444.7 11.7 3.8e-133 444.3 11.7 1.1 1 0 0 1 1 1 1 ALG3 protein PhoLip_ATPase_C PF16212.5 KXS11552.1 - 9.3e-56 189.4 23.8 9.3e-56 189.4 23.8 2.1 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KXS11552.1 - 1.8e-18 66.0 4.6 6.2e-18 64.3 0.1 3.0 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 KXS11552.1 - 7.4e-10 38.8 0.0 2.7e-09 37.0 0.0 1.8 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KXS11552.1 - 2.7e-09 37.6 2.0 5.3e-05 23.6 0.5 3.4 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KXS11552.1 - 2.8e-05 23.7 0.0 0.00048 19.7 0.0 2.5 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KXS11552.1 - 0.014 15.2 1.3 0.1 12.3 1.2 2.1 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase T3SS_LEE_assoc PF13327.6 KXS11552.1 - 0.17 11.9 0.0 0.4 10.7 0.0 1.6 1 0 0 1 1 1 0 Type III secretion system subunit SnoaL_2 PF12680.7 KXS11553.1 - 0.0018 18.9 0.0 0.0049 17.5 0.0 1.7 2 0 0 2 2 2 1 SnoaL-like domain DUF2184 PF09950.9 KXS11553.1 - 0.14 11.6 0.2 0.32 10.3 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2184) PAP2 PF01569.21 KXS11554.1 - 5.3e-23 81.3 2.0 9.7e-23 80.4 0.2 2.1 2 0 0 2 2 2 1 PAP2 superfamily DUF998 PF06197.13 KXS11554.1 - 0.57 9.8 10.2 1.3 8.6 4.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF998) PAP2_3 PF14378.6 KXS11554.1 - 8.1 6.1 13.9 4 7.1 0.4 3.4 3 1 0 3 3 3 0 PAP2 superfamily F-box-like PF12937.7 KXS11555.1 - 0.03 14.2 1.0 0.06 13.3 0.0 2.0 2 0 0 2 2 2 0 F-box-like Cu-oxidase_2 PF07731.14 KXS11556.1 - 1.9e-41 141.0 6.4 6.6e-39 132.8 1.0 2.8 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 KXS11556.1 - 1.2e-37 129.5 0.0 9.4e-33 113.6 0.0 2.3 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KXS11556.1 - 7.9e-33 113.0 5.6 2.1e-28 98.7 0.2 3.7 3 1 0 3 3 3 2 Multicopper oxidase Cupredoxin_1 PF13473.6 KXS11556.1 - 0.0065 16.6 0.0 0.11 12.7 0.0 2.7 3 1 0 3 3 3 1 Cupredoxin-like domain CBM60 PF16841.5 KXS11556.1 - 0.11 12.9 0.0 0.31 11.5 0.0 1.7 1 0 0 1 1 1 0 Ca-dependent carbohydrate-binding module xylan-binding EXS PF03124.14 KXS11558.1 - 7.2e-35 120.9 0.6 8e-35 120.7 0.6 1.0 1 0 0 1 1 1 1 EXS family Methyltransf_24 PF13578.6 KXS11560.1 - 7.8e-06 26.9 0.0 1.2e-05 26.3 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Glyco_transf_4 PF13439.6 KXS11560.1 - 0.1 12.6 0.1 0.14 12.2 0.1 1.1 1 0 0 1 1 1 0 Glycosyltransferase Family 4 adh_short PF00106.25 KXS11565.1 - 8.5e-56 188.5 5.4 1e-55 188.2 5.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXS11565.1 - 7.5e-53 179.5 7.7 8.9e-53 179.2 7.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXS11565.1 - 7.1e-11 42.3 1.6 9.7e-11 41.9 1.6 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXS11565.1 - 0.0082 15.6 0.6 0.013 14.9 0.6 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Glyoxalase_4 PF13669.6 KXS11566.1 - 1.1e-05 25.7 0.0 3.5e-05 24.0 0.0 1.8 2 0 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 KXS11566.1 - 2.9e-05 24.2 0.0 4.3e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_6 PF18029.1 KXS11566.1 - 0.0051 17.6 0.0 2 9.3 0.0 2.4 2 0 0 2 2 2 2 Glyoxalase-like domain AcetylCoA_hyd_C PF13336.6 KXS11567.1 - 1.6e-57 193.7 0.0 2.4e-57 193.2 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain AcetylCoA_hydro PF02550.15 KXS11567.1 - 3.4e-18 66.3 0.0 5.6e-18 65.6 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain DUF1298 PF06974.13 KXS11570.1 - 1.5e-14 54.2 0.0 2.5e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1298) WES_acyltransf PF03007.16 KXS11570.1 - 0.0015 18.4 0.1 0.0037 17.1 0.0 1.6 2 0 0 2 2 2 1 Wax ester synthase-like Acyl-CoA acyltransferase domain AKAP7_NLS PF10469.9 KXS11572.1 - 8.2e-31 107.5 0.0 1.8e-30 106.4 0.0 1.5 1 1 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain 2_5_RNA_ligase2 PF13563.6 KXS11572.1 - 2.7e-08 33.9 0.1 5.3e-08 32.9 0.1 1.4 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily LigT_PEase PF02834.16 KXS11572.1 - 0.047 13.9 0.2 6.4 7.0 0.0 3.0 3 0 0 3 3 3 0 LigT like Phosphoesterase FadA PF09403.10 KXS11573.1 - 0.017 15.6 0.5 0.017 15.6 0.5 1.5 2 0 0 2 2 2 0 Adhesion protein FadA DLP_helical PF18709.1 KXS11573.1 - 0.033 13.4 1.6 0.061 12.5 1.6 1.4 1 0 0 1 1 1 0 Dynamin-like helical domain Spc7 PF08317.11 KXS11573.1 - 0.12 11.3 5.8 0.21 10.4 5.8 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein GAS PF13851.6 KXS11573.1 - 0.14 11.5 4.3 0.28 10.5 4.3 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF5069 PF16798.5 KXS11573.1 - 1.8 8.8 5.9 0.23 11.6 0.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5069) Sedlin_N PF04628.13 KXS11576.1 - 1.1e-25 90.3 0.0 1.3e-25 90.0 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 KXS11576.1 - 0.13 12.2 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 Sybindin-like family Es2 PF09751.9 KXS11577.1 - 1.2e-65 223.0 0.0 1.5e-65 222.6 0.0 1.1 1 0 0 1 1 1 1 Nuclear protein Es2 MFS_1 PF07690.16 KXS11578.1 - 1.7e-20 73.2 36.3 2.1e-19 69.7 36.9 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Cation_efflux PF01545.21 KXS11581.1 - 4.2e-51 173.5 10.1 5.4e-51 173.2 10.1 1.1 1 0 0 1 1 1 1 Cation efflux family Peptidase_M50 PF02163.22 KXS11582.1 - 1e-10 41.4 0.8 0.002 17.4 0.0 3.2 3 0 0 3 3 3 3 Peptidase family M50 PDZ_6 PF17820.1 KXS11582.1 - 0.0028 17.5 0.2 0.0075 16.1 0.2 1.8 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KXS11582.1 - 0.056 13.8 0.3 0.45 10.9 0.1 2.2 2 0 0 2 2 2 0 PDZ domain DUF3712 PF12505.8 KXS11583.1 - 1e-46 158.3 13.8 4e-23 82.0 0.1 5.6 5 0 0 5 5 5 5 Protein of unknown function (DUF3712) LEA_2 PF03168.13 KXS11583.1 - 2e-07 31.5 9.9 0.069 13.7 0.0 4.9 4 0 0 4 4 4 3 Late embryogenesis abundant protein MFS_1 PF07690.16 KXS11585.1 - 2.4e-23 82.7 23.2 2.4e-23 82.7 23.2 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 KXS11585.1 - 1.9e-11 43.2 14.2 4.1e-11 42.1 1.8 3.0 2 1 1 3 3 3 3 MFS/sugar transport protein MFS_1 PF07690.16 KXS11587.1 - 4.1e-10 39.1 3.0 5.1e-10 38.8 3.0 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 KXS11587.1 - 7.7e-07 28.0 0.1 1e-06 27.6 0.1 1.0 1 0 0 1 1 1 1 MFS/sugar transport protein OATP PF03137.20 KXS11587.1 - 0.0076 14.6 0.8 0.011 14.0 0.2 1.4 1 1 1 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family Sec15 PF04091.12 KXS11588.1 - 3.7e-07 29.9 0.2 8.2e-07 28.7 0.0 1.7 2 0 0 2 2 2 1 Exocyst complex subunit Sec15-like Sec8_exocyst PF04048.14 KXS11588.1 - 0.021 14.7 0.7 0.039 13.9 0.7 1.5 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain DUF4055 PF13264.6 KXS11588.1 - 0.085 13.0 2.3 0.11 12.6 0.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4055) COG2 PF06148.11 KXS11588.1 - 0.13 12.3 4.9 0.044 13.9 1.7 1.8 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Pyridoxal_deC PF00282.19 KXS11589.1 - 2.1e-35 122.2 0.0 2.8e-35 121.8 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain ETF PF01012.21 KXS11590.1 - 8.6e-44 149.6 4.4 1.4e-43 148.9 4.4 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 KXS11590.1 - 2.1e-37 127.0 1.4 1.8e-36 124.0 0.4 2.4 2 0 0 2 2 2 1 Electron transfer flavoprotein FAD-binding domain zf-MIZ PF02891.20 KXS11591.1 - 3.9e-19 68.1 1.1 7.9e-19 67.2 1.1 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger PINIT PF14324.6 KXS11591.1 - 3.6e-17 63.1 0.0 7.7e-17 62.0 0.0 1.6 1 0 0 1 1 1 1 PINIT domain zf-Nse PF11789.8 KXS11591.1 - 2.1e-05 24.3 0.4 2.1e-05 24.3 0.4 2.0 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit SAP PF02037.27 KXS11591.1 - 0.0055 16.4 0.5 0.01 15.5 0.5 1.5 1 0 0 1 1 1 1 SAP domain Rad50_zn_hook PF04423.14 KXS11591.1 - 0.045 13.6 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 Rad50 zinc hook motif Prok-RING_4 PF14447.6 KXS11591.1 - 0.098 12.5 0.6 0.19 11.6 0.6 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 NTP_transf_3 PF12804.7 KXS11592.1 - 2.4e-08 34.5 0.0 3.8e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.23 KXS11592.1 - 1.3e-06 28.2 0.0 1.9e-06 27.7 0.0 1.4 1 1 0 1 1 1 1 Nucleotidyl transferase SH3_1 PF00018.28 KXS11594.1 - 4.9e-07 29.3 0.0 7.6e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KXS11594.1 - 2.1e-06 27.5 0.0 3.7e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KXS11594.1 - 2.4e-06 27.1 0.0 4.4e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Ion_trans_2 PF07885.16 KXS11595.1 - 0.15 12.1 0.4 0.15 12.1 0.4 2.5 2 1 1 3 3 3 0 Ion channel Chromate_transp PF02417.15 KXS11595.1 - 0.16 12.1 5.9 0.63 10.2 5.9 1.8 1 1 0 1 1 1 0 Chromate transporter Peptidase_C12 PF01088.21 KXS11596.1 - 5.8e-57 192.8 0.0 6.9e-57 192.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Ribosomal_S3Ae PF01015.18 KXS11597.1 - 5.5e-92 306.9 3.3 6.6e-92 306.6 3.3 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Abhydro_lipase PF04083.16 KXS11597.1 - 0.16 11.6 0.1 0.32 10.6 0.1 1.5 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region DUF2418 PF10332.9 KXS11598.1 - 6.8e-23 81.0 0.1 2e-22 79.5 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2418) HD PF01966.22 KXS11599.1 - 2.7e-10 40.5 0.1 7.5e-10 39.1 0.1 1.8 1 0 0 1 1 1 1 HD domain HTH_1 PF00126.27 KXS11599.1 - 0.047 13.7 0.0 0.098 12.6 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family V-SNARE_C PF12352.8 KXS11600.1 - 1.8e-06 28.1 2.6 2.1e-06 27.9 1.0 1.9 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus V-SNARE PF05008.15 KXS11600.1 - 1.9e-06 28.1 1.8 1.9e-06 28.1 1.8 2.5 2 1 1 3 3 3 1 Vesicle transport v-SNARE protein N-terminus Sec20 PF03908.13 KXS11600.1 - 8.1e-06 25.7 0.8 8.4e-05 22.4 0.2 2.5 2 1 1 3 3 3 1 Sec20 SNARE PF05739.19 KXS11600.1 - 0.00018 21.4 0.3 0.00052 20.0 0.3 1.8 1 0 0 1 1 1 1 SNARE domain ApoLp-III PF07464.11 KXS11600.1 - 0.0016 18.5 0.5 1.3 9.1 0.0 2.8 2 1 1 3 3 3 2 Apolipophorin-III precursor (apoLp-III) T3SS_needle_E PF08988.10 KXS11600.1 - 0.0016 18.5 0.5 0.49 10.6 0.0 2.7 3 0 0 3 3 3 1 Type III secretion system, cytoplasmic E component of needle DMPK_coil PF08826.10 KXS11600.1 - 0.036 14.2 5.9 4 7.6 0.1 3.5 3 0 0 3 3 3 0 DMPK coiled coil domain like DUF4200 PF13863.6 KXS11600.1 - 0.044 14.2 0.5 0.044 14.2 0.5 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) Use1 PF09753.9 KXS11600.1 - 0.05 13.3 6.2 3.7 7.2 6.2 2.1 1 1 0 1 1 1 0 Membrane fusion protein Use1 Cytochrom_B562 PF07361.11 KXS11600.1 - 0.056 14.1 5.2 3.2 8.5 0.2 3.1 1 1 2 3 3 3 0 Cytochrome b562 Tropomyosin PF00261.20 KXS11600.1 - 0.063 12.6 8.9 0.02 14.3 1.9 2.2 2 0 0 2 2 2 0 Tropomyosin OppC_N PF12911.7 KXS11600.1 - 0.11 12.5 0.6 0.17 11.9 0.6 1.3 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C DUF1759 PF03564.15 KXS11600.1 - 0.12 12.3 1.9 1.2 9.1 0.3 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1759) TSP_NTD PF17804.1 KXS11600.1 - 0.32 11.3 4.5 0.51 10.6 4.5 1.4 1 1 0 1 1 1 0 Tail specific protease N-terminal domain UPF0172 PF03665.13 KXS11601.1 - 2.6e-44 151.5 0.0 3.1e-44 151.3 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) MRG PF05712.13 KXS11602.1 - 1.9e-56 190.6 1.0 2.9e-56 189.9 1.0 1.3 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.8 KXS11602.1 - 1.6e-08 34.3 0.1 2.9e-08 33.5 0.1 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.24 KXS11602.1 - 0.0025 17.7 0.3 0.0073 16.2 0.3 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain S-antigen PF05756.11 KXS11602.1 - 0.23 11.9 1.2 8 6.9 0.0 2.4 2 0 0 2 2 2 0 S-antigen protein SQHop_cyclase_C PF13243.6 KXS11604.1 - 6.5e-51 173.3 1.4 4.3e-47 160.8 0.5 2.4 2 1 0 2 2 2 2 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 KXS11604.1 - 7.1e-45 153.3 0.0 1e-38 133.1 0.0 3.9 3 1 1 4 4 4 3 Squalene-hopene cyclase N-terminal domain Prenyltrans PF00432.21 KXS11604.1 - 3.8e-32 109.7 12.3 2.4e-10 40.0 0.0 6.2 5 1 0 5 5 5 3 Prenyltransferase and squalene oxidase repeat Mago-bind PF09282.10 KXS11604.1 - 0.0064 16.3 0.1 0.019 14.8 0.1 1.9 1 0 0 1 1 1 1 Mago binding Pec_lyase PF09492.10 KXS11604.1 - 0.089 12.1 0.1 15 4.8 0.0 3.8 5 0 0 5 5 5 0 Pectic acid lyase Putative_PNPOx PF01243.20 KXS11605.1 - 0.029 14.5 0.0 0.043 14.0 0.0 1.2 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase LRR_6 PF13516.6 KXS11606.1 - 2.4e-11 42.7 4.9 0.41 10.8 0.0 5.8 6 0 0 6 6 6 4 Leucine Rich repeat LRR_4 PF12799.7 KXS11606.1 - 2e-05 24.9 2.3 0.53 10.8 0.4 4.2 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) DUF1722 PF08349.11 KXS11606.1 - 0.0058 16.9 2.6 0.14 12.4 0.1 2.7 1 1 0 2 2 2 1 Protein of unknown function (DUF1722) Apolipoprotein PF01442.18 KXS11606.1 - 0.013 15.4 2.7 0.013 15.4 2.7 1.8 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain LPD5 PF18799.1 KXS11606.1 - 0.022 15.2 2.3 0.061 13.7 0.2 2.3 2 0 0 2 2 2 0 Large polyvalent protein-associated domain 5 Muted PF14942.6 KXS11606.1 - 0.048 14.0 6.9 0.039 14.3 3.8 2.3 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein FapA PF03961.13 KXS11606.1 - 0.16 10.5 6.6 0.044 12.4 3.3 1.7 2 0 0 2 2 2 0 Flagellar Assembly Protein A DUF1664 PF07889.12 KXS11606.1 - 0.94 9.5 8.8 0.96 9.5 4.5 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 KXS11606.1 - 5.7 7.1 10.4 2.5 8.3 6.8 2.2 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family MFS_1 PF07690.16 KXS11607.1 - 1.4e-24 86.7 58.2 5.5e-18 65.0 26.8 2.7 1 1 2 3 3 3 2 Major Facilitator Superfamily DUF1158 PF06643.11 KXS11607.1 - 1.3 9.5 5.2 2.6 8.6 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1158) Abhydrolase_6 PF12697.7 KXS11608.1 - 2.6e-20 74.0 1.0 3.3e-20 73.6 1.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXS11608.1 - 8e-16 58.5 0.0 6.2e-15 55.5 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXS11608.1 - 2.4e-13 49.9 0.0 3.1e-13 49.6 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Palm_thioest PF02089.15 KXS11608.1 - 0.0016 18.3 0.0 0.0081 16.0 0.0 1.9 2 0 0 2 2 2 1 Palmitoyl protein thioesterase BAAT_C PF08840.11 KXS11608.1 - 0.0025 17.8 0.0 0.0086 16.0 0.0 1.7 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal PGAP1 PF07819.13 KXS11608.1 - 0.0036 17.0 1.3 0.18 11.5 0.1 2.6 2 1 1 3 3 3 1 PGAP1-like protein Abhydrolase_8 PF06259.12 KXS11608.1 - 0.0049 16.5 0.9 0.024 14.2 0.0 2.4 3 0 0 3 3 3 1 Alpha/beta hydrolase Abhydrolase_3 PF07859.13 KXS11608.1 - 0.011 15.6 0.0 0.025 14.5 0.0 1.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KXS11608.1 - 0.018 14.5 0.0 5.3 6.4 0.0 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family Thioesterase PF00975.20 KXS11608.1 - 0.079 13.1 0.0 0.2 11.8 0.0 1.6 2 0 0 2 2 2 0 Thioesterase domain Lipase_3 PF01764.25 KXS11608.1 - 0.097 12.5 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_2 PF02230.16 KXS11608.1 - 0.17 11.7 0.1 2.1 8.1 0.1 2.3 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Penicil_amidase PF01804.18 KXS11609.1 - 1.6e-169 566.1 0.0 1.8e-169 565.9 0.0 1.0 1 0 0 1 1 1 1 Penicillin amidase BUD22 PF09073.10 KXS11610.1 - 5.1e-10 39.3 39.3 5.1e-10 39.3 39.3 3.1 1 1 1 2 2 2 1 BUD22 Metallophos PF00149.28 KXS11611.1 - 1.4e-33 117.1 0.0 2.3e-33 116.4 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase zf-CCCH_2 PF14608.6 KXS11612.1 - 0.019 15.4 7.2 0.18 12.3 0.8 2.3 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger PPR PF01535.20 KXS11613.1 - 0.00041 20.4 0.4 0.14 12.5 0.0 4.0 4 0 0 4 4 4 1 PPR repeat TPR_14 PF13428.6 KXS11613.1 - 0.071 14.0 0.7 5.6 8.1 0.1 3.5 3 1 1 4 4 4 0 Tetratricopeptide repeat FCH PF00611.23 KXS11614.1 - 9.7e-11 41.8 0.0 1.3e-10 41.4 0.0 1.2 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain JmjC PF02373.22 KXS11615.1 - 2.2e-08 34.5 0.0 3e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 KXS11615.1 - 1.1e-05 25.3 0.0 1.4e-05 25.0 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 KXS11615.1 - 0.0032 17.0 0.0 0.0034 16.9 0.0 1.1 1 0 0 1 1 1 1 Cupin superfamily protein Pkinase PF00069.25 KXS11616.1 - 6.7e-74 248.6 0.0 7.9e-74 248.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS11616.1 - 4e-36 124.6 0.0 5.1e-36 124.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXS11616.1 - 2.1e-06 27.3 0.0 2.6e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KXS11616.1 - 0.00019 20.3 0.0 0.0012 17.7 0.0 1.9 1 1 1 2 2 2 1 Fungal protein kinase Kdo PF06293.14 KXS11616.1 - 0.0046 16.3 0.0 0.0075 15.6 0.0 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Exo_endo_phos PF03372.23 KXS11617.1 - 5.2e-06 26.2 0.0 7.8e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family PMD PF10536.9 KXS11620.1 - 0.021 13.9 0.0 0.023 13.8 0.0 1.1 1 0 0 1 1 1 0 Plant mobile domain TGF_beta_GS PF08515.12 KXS11621.1 - 0.022 14.2 1.7 0.04 13.4 0.1 2.3 2 0 0 2 2 2 0 Transforming growth factor beta type I GS-motif DUF1179 PF06678.11 KXS11621.1 - 0.19 11.7 0.2 0.45 10.5 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1179) Tubulin PF00091.25 KXS11622.1 - 2.4e-69 233.5 0.0 4.7e-69 232.5 0.0 1.5 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KXS11622.1 - 3.6e-43 146.7 0.1 5.6e-43 146.1 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 KXS11622.1 - 1.1e-05 25.7 0.1 3e-05 24.3 0.0 1.8 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 KXS11622.1 - 0.0011 18.7 0.0 0.0022 17.7 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 KXS11622.1 - 0.017 14.3 0.0 0.056 12.6 0.0 1.8 2 0 0 2 2 2 0 Tubulin like Hamartin PF04388.12 KXS11624.1 - 0.81 8.3 32.2 1 7.9 32.2 1.0 1 0 0 1 1 1 0 Hamartin protein TFIIS_M PF07500.14 KXS11625.1 - 2e-25 89.5 0.6 3.8e-25 88.5 0.6 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain SPOC PF07744.13 KXS11625.1 - 7.3e-18 64.9 0.0 1.5e-17 63.9 0.0 1.5 1 0 0 1 1 1 1 SPOC domain PHD PF00628.29 KXS11625.1 - 1e-09 38.1 8.2 1.8e-09 37.3 8.2 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KXS11625.1 - 0.31 10.6 4.2 0.57 9.8 4.2 1.4 1 0 0 1 1 1 0 PHD-finger cwf18 PF08315.12 KXS11626.1 - 3.2e-26 92.6 8.8 4.1e-26 92.3 8.8 1.1 1 0 0 1 1 1 1 cwf18 pre-mRNA splicing factor TLP1_add_C PF18313.1 KXS11626.1 - 0.054 13.4 0.1 0.095 12.7 0.1 1.4 1 0 0 1 1 1 0 Thiolase-like protein type 1 additional C-terminal domain PHD PF00628.29 KXS11627.1 - 1.1e-10 41.2 7.9 1.8e-10 40.5 7.9 1.3 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KXS11627.1 - 1.2e-06 28.0 1.9 2.1e-06 27.2 1.9 1.4 1 0 0 1 1 1 1 PHD-finger BAH PF01426.18 KXS11627.1 - 2.5e-05 24.1 0.0 4.1e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 BAH domain zf-H2C2_2 PF13465.6 KXS11627.1 - 0.018 15.4 1.5 8 7.1 0.0 2.6 2 0 0 2 2 2 0 Zinc-finger double domain zf-4CXXC_R1 PF10497.9 KXS11627.1 - 0.1 12.8 1.1 0.16 12.2 1.1 1.3 1 0 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 zf-CW PF07496.15 KXS11627.1 - 0.27 11.3 10.1 0.079 13.0 6.2 2.1 2 1 0 2 2 2 0 CW-type Zinc Finger C1_1 PF00130.22 KXS11627.1 - 0.34 10.8 5.2 0.067 13.1 1.4 1.8 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Zf_RING PF16744.5 KXS11627.1 - 0.81 9.8 3.8 15 5.8 3.8 2.3 1 1 0 1 1 1 0 KIAA1045 RING finger PHD_4 PF16866.5 KXS11627.1 - 1.6 8.9 7.7 3 8.0 7.7 1.5 1 0 0 1 1 1 0 PHD-finger zf-RING_2 PF13639.6 KXS11627.1 - 3.7 8.0 7.4 7.1 7.0 7.4 1.5 1 0 0 1 1 1 0 Ring finger domain KH_1 PF00013.29 KXS11628.1 - 9.2e-10 38.2 0.0 2.6e-08 33.6 0.0 2.4 2 0 0 2 2 2 1 KH domain RF-1 PF00472.20 KXS11628.1 - 0.13 12.2 0.7 0.37 10.7 0.1 2.1 2 0 0 2 2 2 0 RF-1 domain Ribosomal_L9_C PF03948.14 KXS11629.1 - 0.00072 20.0 0.1 0.0027 18.1 0.1 2.1 2 1 0 2 2 2 1 Ribosomal protein L9, C-terminal domain Ribosomal_L9_N PF01281.19 KXS11629.1 - 0.00072 19.1 0.0 0.0013 18.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain DEAD PF00270.29 KXS11630.1 - 9e-39 133.0 0.0 6.5e-37 127.0 0.0 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXS11630.1 - 7.7e-19 68.1 0.0 2.1e-18 66.7 0.0 1.8 1 1 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KXS11630.1 - 4.9e-17 61.9 0.1 1.1e-16 60.8 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KXS11630.1 - 0.0026 17.8 0.0 0.0068 16.4 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KXS11630.1 - 0.089 13.1 0.0 1.1 9.5 0.0 2.5 3 0 0 3 3 3 0 AAA domain DNA_ligase_A_M PF01068.21 KXS11631.1 - 3e-47 160.9 0.0 6.9e-47 159.7 0.0 1.6 1 1 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KXS11631.1 - 8.4e-33 114.1 0.1 1.3e-32 113.6 0.1 1.3 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 KXS11631.1 - 1.7e-21 76.6 0.0 5.6e-21 75.0 0.0 1.9 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region mRNA_cap_enzyme PF01331.19 KXS11631.1 - 0.00046 20.1 0.0 0.39 10.5 0.0 2.2 2 0 0 2 2 2 2 mRNA capping enzyme, catalytic domain Methyltransf_4 PF02390.17 KXS11632.1 - 6.6e-51 172.2 0.0 8.6e-51 171.8 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 KXS11632.1 - 0.0066 17.1 0.0 0.017 15.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXS11632.1 - 0.015 14.8 0.0 0.038 13.5 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_31 PF13847.6 KXS11632.1 - 0.029 14.2 0.0 0.06 13.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.20 KXS11632.1 - 0.032 13.5 0.0 0.097 11.9 0.0 1.7 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 KXS11632.1 - 0.096 13.4 0.0 0.21 12.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.6 KXS11632.1 - 0.16 11.9 0.0 0.25 11.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain WD40 PF00400.32 KXS11633.1 - 9e-27 92.8 24.0 0.00022 22.0 0.9 7.0 6 1 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXS11633.1 - 5.8e-09 36.1 4.5 0.028 14.7 0.1 4.9 3 2 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KXS11633.1 - 0.092 11.7 3.4 2.6 6.9 0.1 3.8 3 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein LSM PF01423.22 KXS11634.1 - 1.1e-18 66.7 0.5 1.4e-18 66.3 0.5 1.2 1 0 0 1 1 1 1 LSM domain DUF150_C PF17384.2 KXS11634.1 - 0.0015 18.6 1.5 0.0026 17.9 1.5 1.4 1 1 0 1 1 1 1 RimP C-terminal SH3 domain P-II PF00543.22 KXS11634.1 - 0.016 15.8 0.1 0.017 15.7 0.1 1.1 1 0 0 1 1 1 0 Nitrogen regulatory protein P-II Ribosomal_L18A PF01775.17 KXS11635.1 - 1.1e-53 180.5 1.4 1.1e-28 99.8 0.1 2.1 2 0 0 2 2 2 2 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A eIF-5a PF01287.20 KXS11636.1 - 1.6e-29 101.8 0.4 2.3e-29 101.3 0.4 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 KXS11636.1 - 0.0062 16.5 0.3 0.04 13.9 0.1 2.1 2 0 0 2 2 2 1 Elongation factor P (EF-P) KOW-like domain Tubulin_3 PF14881.6 KXS11637.1 - 2.9e-28 98.8 0.3 3.6e-23 82.2 0.0 2.2 2 0 0 2 2 2 2 Tubulin domain Misat_Tub_SegII PF10644.9 KXS11637.1 - 1.2e-23 83.7 0.0 6.3e-23 81.3 0.0 2.2 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin PF00091.25 KXS11637.1 - 0.0038 17.4 0.0 1 9.5 0.0 2.4 2 0 0 2 2 2 2 Tubulin/FtsZ family, GTPase domain Fis1_TPR_C PF14853.6 KXS11638.1 - 1.7e-21 76.1 0.2 2.7e-21 75.4 0.2 1.3 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 KXS11638.1 - 1.5e-11 43.7 0.1 3.2e-11 42.7 0.1 1.6 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.17 KXS11638.1 - 8.2e-05 22.4 0.2 0.00025 20.9 0.1 1.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 KXS11638.1 - 0.045 14.3 0.0 0.064 13.8 0.0 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat Ax_dynein_light PF10211.9 KXS11639.1 - 2.7e-05 24.2 0.9 2.7e-05 24.2 0.9 3.0 3 1 0 3 3 3 1 Axonemal dynein light chain TetR_C_13 PF16925.5 KXS11639.1 - 0.046 13.6 0.2 0.29 11.1 0.0 2.4 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Virulence_fact PF13769.6 KXS11639.1 - 0.63 10.3 4.4 0.76 10.1 1.3 2.8 3 0 0 3 3 3 0 Virulence factor DUF445 PF04286.12 KXS11639.1 - 3.6 7.3 7.2 1.9 8.2 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF445) PAXX PF15384.6 KXS11640.1 - 0.00015 21.5 0.1 0.0018 18.0 0.0 2.0 2 0 0 2 2 2 1 PAXX, PAralog of XRCC4 and XLF, also called C9orf142 Glyco_tran_WecB PF03808.13 KXS11640.1 - 0.069 13.1 0.0 1.4 8.8 0.0 2.5 1 1 1 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family zf-RING_2 PF13639.6 KXS11642.1 - 2.8e-13 49.9 4.2 2.8e-13 49.9 4.2 2.1 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 KXS11642.1 - 1.4e-09 37.7 4.7 1.4e-09 37.7 4.7 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KXS11642.1 - 2.9e-08 33.3 1.5 8.3e-08 31.8 1.5 1.8 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 KXS11642.1 - 1.7e-07 31.4 4.5 1.7e-07 31.4 4.5 2.3 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KXS11642.1 - 5.1e-07 29.5 2.1 5.1e-07 29.5 2.1 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KXS11642.1 - 2.1e-06 27.5 5.6 7e-05 22.6 1.4 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_9 PF14369.6 KXS11642.1 - 3.8e-06 27.0 2.3 3.8e-06 27.0 2.3 2.2 2 0 0 2 2 2 1 zinc-ribbon zf-RING_UBOX PF13445.6 KXS11642.1 - 4.4e-06 26.6 0.3 4.4e-06 26.6 0.3 2.0 2 1 0 2 2 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KXS11642.1 - 3e-05 23.8 2.0 3e-05 23.8 2.0 2.2 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KXS11642.1 - 0.00044 20.1 2.0 0.00044 20.1 2.0 2.2 2 0 0 2 2 2 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 KXS11642.1 - 0.00065 19.3 3.5 0.00065 19.3 3.5 2.0 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 KXS11642.1 - 0.0011 19.0 0.9 0.0024 17.9 0.9 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING-like PF08746.11 KXS11642.1 - 0.031 14.6 3.6 0.031 14.6 3.6 2.0 2 0 0 2 2 2 0 RING-like domain FANCL_C PF11793.8 KXS11642.1 - 0.088 13.0 4.8 0.92 9.7 4.8 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain NOB1_Zn_bind PF08772.11 KXS11642.1 - 0.11 12.7 0.2 0.24 11.6 0.2 1.5 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like DZR PF12773.7 KXS11642.1 - 0.38 10.8 5.2 0.81 9.8 0.4 2.6 2 1 0 2 2 2 0 Double zinc ribbon zinc-ribbons_6 PF07191.12 KXS11642.1 - 0.49 10.4 6.1 1.2 9.1 0.6 2.4 2 1 0 2 2 2 0 zinc-ribbons HypA PF01155.19 KXS11642.1 - 1.2 9.2 5.0 2.1 8.4 0.4 2.3 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C2HC5 PF06221.13 KXS11642.1 - 1.5 8.9 5.1 0.57 10.2 0.2 2.5 3 0 0 3 3 3 0 Putative zinc finger motif, C2HC5-type zf-RING_10 PF16685.5 KXS11642.1 - 1.8 8.7 6.7 3.1 8.0 2.0 2.2 2 0 0 2 2 2 0 zinc RING finger of MSL2 Prok-RING_1 PF14446.6 KXS11642.1 - 2 8.4 12.5 1.8 8.6 3.1 3.2 2 1 1 3 3 3 0 Prokaryotic RING finger family 1 zf-P11 PF03854.14 KXS11642.1 - 5.8 6.7 8.7 5.6 6.7 1.1 2.3 2 0 0 2 2 2 0 P-11 zinc finger TPR_14 PF13428.6 KXS11643.1 - 6.1e-10 39.1 13.6 0.13 13.2 0.0 10.9 10 2 1 11 11 11 2 Tetratricopeptide repeat Suf PF05843.14 KXS11643.1 - 2.7e-07 30.9 2.2 0.11 12.5 0.0 5.6 6 1 0 6 6 6 2 Suppressor of forked protein (Suf) TPR_8 PF13181.6 KXS11643.1 - 5e-06 26.3 1.3 0.056 13.7 0.1 5.2 6 0 0 6 6 5 2 Tetratricopeptide repeat RPN7 PF10602.9 KXS11643.1 - 9.3e-06 25.5 0.0 0.047 13.4 0.0 3.2 3 0 0 3 3 3 2 26S proteasome subunit RPN7 Mad3_BUB1_I PF08311.12 KXS11643.1 - 2e-05 24.6 8.1 3.9 7.5 0.0 5.9 7 0 0 7 7 7 2 Mad3/BUB1 homology region 1 TPR_2 PF07719.17 KXS11643.1 - 5.4e-05 23.0 8.3 0.0053 16.8 0.2 6.9 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_19 PF14559.6 KXS11643.1 - 9.5e-05 22.8 5.0 2.5 8.7 0.0 5.6 5 1 1 6 6 6 1 Tetratricopeptide repeat NRDE-2 PF08424.10 KXS11643.1 - 0.0016 17.6 3.1 2 7.5 0.0 4.4 3 1 1 4 4 4 1 NRDE-2, necessary for RNA interference TPR_7 PF13176.6 KXS11643.1 - 0.0052 16.7 4.9 0.16 12.1 0.0 5.1 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_12 PF13424.6 KXS11643.1 - 0.026 14.8 2.6 0.46 10.8 0.0 4.0 4 0 0 4 4 3 0 Tetratricopeptide repeat SNAP PF14938.6 KXS11643.1 - 0.038 13.4 3.7 2.8 7.3 0.1 3.5 3 1 0 3 3 3 0 Soluble NSF attachment protein, SNAP TPR_17 PF13431.6 KXS11643.1 - 0.05 14.0 0.1 7.8 7.1 0.0 4.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 KXS11643.1 - 0.054 13.3 7.4 0.069 13.0 0.1 4.5 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_10 PF13374.6 KXS11643.1 - 0.12 12.3 0.0 0.12 12.3 0.0 3.8 4 0 0 4 4 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 KXS11643.1 - 0.2 12.4 6.9 4 8.3 0.1 6.0 7 0 0 7 7 5 0 Tetratricopeptide repeat VPS28 PF03997.12 KXS11644.1 - 9e-38 129.9 0.0 7.5e-25 87.7 0.0 2.0 1 1 1 2 2 2 2 VPS28 protein IFT46_B_C PF12317.8 KXS11644.1 - 0.035 13.9 0.0 0.4 10.4 0.0 2.1 1 1 1 2 2 2 0 Intraflagellar transport complex B protein 46 C terminal DUF3349 PF11829.8 KXS11644.1 - 0.054 14.3 0.1 0.22 12.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3349) VPS28 PF03997.12 KXS11645.1 - 5.4e-29 101.2 0.0 6.4e-29 101.0 0.0 1.0 1 0 0 1 1 1 1 VPS28 protein YadA_stalk PF05662.14 KXS11645.1 - 0.037 14.4 0.9 0.073 13.4 0.2 1.8 2 0 0 2 2 2 0 Coiled stalk of trimeric autotransporter adhesin RabGAP-TBC PF00566.18 KXS11646.1 - 2.9e-35 121.9 0.0 4.3e-35 121.3 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Pkinase PF00069.25 KXS11646.1 - 6e-35 120.9 0.0 8.7e-35 120.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS11646.1 - 3.2e-22 79.1 0.0 5.2e-22 78.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXS11646.1 - 0.0002 20.8 0.0 0.00034 20.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like MatE PF01554.18 KXS11647.1 - 1.9e-47 160.9 34.8 1.1e-24 86.9 7.1 2.6 3 0 0 3 3 3 2 MatE PGAP1 PF07819.13 KXS11649.1 - 9.2e-72 241.5 0.1 1.2e-71 241.1 0.1 1.1 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 KXS11649.1 - 0.00021 22.0 0.0 0.00031 21.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.14 KXS11649.1 - 0.0084 15.6 0.0 0.026 14.0 0.0 1.7 2 0 0 2 2 2 1 Putative serine esterase (DUF676) Abhydrolase_1 PF00561.20 KXS11649.1 - 0.052 13.2 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 KXS11649.1 - 0.14 11.9 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXS11649.1 - 0.15 11.3 0.0 0.31 10.3 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Adaptin_N PF01602.20 KXS11652.1 - 1.6e-76 257.9 0.0 3.9e-73 246.8 0.0 2.0 2 0 0 2 2 2 2 Adaptin N terminal region Cnd1 PF12717.7 KXS11652.1 - 3.8e-16 59.5 0.1 5.3e-14 52.6 0.0 2.7 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KXS11652.1 - 1.3e-09 38.3 9.2 3.3e-05 24.2 0.4 4.3 2 1 2 4 4 4 4 HEAT repeats HEAT PF02985.22 KXS11652.1 - 7.1e-09 35.2 0.6 0.04 14.2 0.0 5.4 5 0 0 5 5 4 2 HEAT repeat HEAT_EZ PF13513.6 KXS11652.1 - 9.8e-06 26.0 7.2 0.047 14.2 0.1 4.1 3 1 0 3 3 3 2 HEAT-like repeat Cnd3 PF12719.7 KXS11652.1 - 0.11 11.6 0.1 4.2 6.5 0.0 2.8 2 1 1 3 3 3 0 Nuclear condensing complex subunits, C-term domain HEAT_UF PF18817.1 KXS11652.1 - 0.14 12.4 0.0 1.1 9.6 0.1 2.5 2 0 0 2 2 2 0 Repeat of uncharacterized protein PH0542 PPP4R2 PF09184.11 KXS11652.1 - 0.45 10.1 9.3 0.79 9.3 9.3 1.4 1 0 0 1 1 1 0 PPP4R2 Sporozoite_P67 PF05642.11 KXS11652.1 - 2.8 5.9 7.8 4.6 5.2 7.8 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CDC45 PF02724.14 KXS11652.1 - 4.6 5.4 9.7 6.9 4.8 9.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 KXS11652.1 - 9.4 4.3 14.2 14 3.7 14.2 1.2 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 KXS11653.1 - 8.6e-118 394.5 36.5 4.2e-62 210.4 0.0 3.8 3 1 1 4 4 4 3 DNA polymerase phi Zip PF02535.22 KXS11653.1 - 0.43 9.7 6.5 0.61 9.2 0.4 3.1 3 0 0 3 3 3 0 ZIP Zinc transporter RRN3 PF05327.11 KXS11653.1 - 0.57 8.7 15.3 1.3 7.5 12.6 2.3 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 Nop14 PF04147.12 KXS11653.1 - 3.3 5.8 29.6 0.061 11.5 19.0 2.5 2 0 0 2 2 2 0 Nop14-like family Ribosomal_L1 PF00687.21 KXS11654.1 - 1.5e-61 207.8 0.1 1.5e-61 207.8 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein L1p/L10e family PBP1_TM PF14812.6 KXS11654.1 - 0.14 12.5 7.3 0.38 11.1 7.3 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Zip PF02535.22 KXS11654.1 - 1.1 8.4 3.4 1.6 7.9 3.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter MCM_bind PF09739.9 KXS11654.1 - 1.7 7.0 8.7 2.4 6.5 8.7 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Epimerase PF01370.21 KXS11655.1 - 8e-53 179.4 0.0 1e-52 179.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXS11655.1 - 1.2e-48 166.3 0.0 3.6e-48 164.7 0.0 1.8 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KXS11655.1 - 4e-15 55.6 0.0 3.1e-14 52.6 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KXS11655.1 - 7.3e-14 51.6 0.0 9.1e-13 48.0 0.0 2.3 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KXS11655.1 - 8.4e-11 41.5 0.0 1.2e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 KXS11655.1 - 2.1e-07 31.0 0.0 4e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KXS11655.1 - 1.1e-05 24.8 0.1 0.084 12.0 0.0 2.6 2 1 0 2 2 2 2 Male sterility protein NmrA PF05368.13 KXS11655.1 - 4.1e-05 23.2 0.1 0.0019 17.8 0.1 2.2 2 0 0 2 2 2 1 NmrA-like family KR PF08659.10 KXS11655.1 - 0.00032 20.7 0.3 0.012 15.5 0.1 2.3 2 0 0 2 2 2 1 KR domain adh_short PF00106.25 KXS11655.1 - 0.013 15.0 0.4 0.021 14.3 0.1 1.5 2 0 0 2 2 2 0 short chain dehydrogenase DapB_N PF01113.20 KXS11655.1 - 0.038 14.1 0.1 0.061 13.4 0.1 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Sacchrp_dh_NADP PF03435.18 KXS11655.1 - 0.12 12.7 0.1 0.23 11.7 0.1 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 KXS11655.1 - 0.13 12.5 0.3 0.34 11.2 0.1 1.7 2 0 0 2 2 1 0 TrkA-N domain Aph-1 PF06105.12 KXS11656.1 - 6.2e-57 192.7 15.9 7.4e-57 192.4 15.9 1.0 1 0 0 1 1 1 1 Aph-1 protein NPR3 PF03666.13 KXS11657.1 - 6.9e-52 176.8 0.0 5.4e-44 150.8 0.0 2.3 2 0 0 2 2 2 2 Nitrogen Permease regulator of amino acid transport activity 3 BP28CT PF08146.12 KXS11658.1 - 1.5e-27 96.4 2.9 1.1e-26 93.6 0.0 3.7 4 0 0 4 4 4 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.8 KXS11658.1 - 5.9e-18 65.3 7.3 2.5e-16 60.1 0.1 5.4 5 0 0 5 5 5 1 U3 small nucleolar RNA-associated protein 10 Gly_transf_sug PF04488.15 KXS11658.1 - 3.1e-08 34.1 0.0 1e-07 32.5 0.0 1.9 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif HEAT_2 PF13646.6 KXS11658.1 - 3.6e-08 33.7 0.1 0.037 14.4 0.0 4.5 3 0 0 3 3 3 2 HEAT repeats Cnd1 PF12717.7 KXS11658.1 - 0.00012 22.2 2.1 4 7.5 0.0 6.0 4 2 2 6 6 6 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KXS11658.1 - 0.0012 18.9 3.5 61 4.3 0.0 6.3 7 0 0 7 7 7 0 HEAT repeat Caps_synth PF05704.12 KXS11658.1 - 0.0095 15.3 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein TcdA_TcdB PF12919.7 KXS11658.1 - 0.012 14.9 1.7 0.026 13.8 0.1 2.1 2 1 0 3 3 3 0 TcdA/TcdB catalytic glycosyltransferase domain HEAT_EZ PF13513.6 KXS11658.1 - 0.072 13.6 4.2 5.6 7.6 0.0 5.5 5 1 0 5 5 5 0 HEAT-like repeat RTP1_C1 PF10363.9 KXS11658.1 - 0.24 11.6 7.0 4.1 7.6 0.0 5.0 5 0 0 5 5 5 0 Required for nuclear transport of RNA pol II C-terminus 1 Mito_carr PF00153.27 KXS11659.1 - 8.7e-72 237.1 1.4 7.1e-25 86.8 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein SRP54 PF00448.22 KXS11660.1 - 7.6e-52 175.8 0.4 1.5e-51 174.9 0.4 1.5 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.19 KXS11660.1 - 2.1e-11 43.8 0.0 5.7e-11 42.5 0.0 1.8 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain MeaB PF03308.16 KXS11660.1 - 5.5e-05 22.3 0.1 0.00023 20.3 0.1 1.9 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_33 PF13671.6 KXS11660.1 - 0.00064 19.9 0.1 0.0026 17.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KXS11660.1 - 0.00094 18.9 0.0 0.0016 18.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 KXS11660.1 - 0.007 16.8 0.0 0.027 14.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 KXS11660.1 - 0.017 15.0 0.4 0.1 12.5 0.4 2.1 1 1 0 1 1 1 0 NTPase CbiA PF01656.23 KXS11660.1 - 0.021 14.9 0.1 0.13 12.3 0.1 2.1 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain APS_kinase PF01583.20 KXS11660.1 - 0.023 14.6 0.0 0.05 13.5 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase NACHT PF05729.12 KXS11660.1 - 0.049 13.6 0.0 0.2 11.6 0.0 1.9 2 0 0 2 2 2 0 NACHT domain AAA_24 PF13479.6 KXS11660.1 - 0.083 12.6 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KXS11660.1 - 0.084 12.8 0.1 0.73 9.7 0.0 2.3 2 2 0 2 2 2 0 RsgA GTPase Zeta_toxin PF06414.12 KXS11660.1 - 0.16 11.2 0.0 0.41 9.9 0.0 1.7 1 1 0 1 1 1 0 Zeta toxin DUF4050 PF13259.6 KXS11664.1 - 1.4e-06 28.7 0.2 0.00015 22.1 0.0 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF4050) SUZ PF12752.7 KXS11665.1 - 3.5e-09 37.3 0.1 9.3e-09 35.9 0.0 1.7 2 0 0 2 2 2 1 SUZ domain LOH1CR12 PF10158.9 KXS11666.1 - 1.5e-11 44.5 0.1 2.7e-11 43.6 0.1 1.4 1 0 0 1 1 1 1 Tumour suppressor protein PIN_4 PF13638.6 KXS11666.1 - 5.4e-06 26.7 0.2 0.00018 21.8 0.2 2.5 1 1 0 1 1 1 1 PIN domain DUF3915 PF13054.6 KXS11666.1 - 0.13 12.3 10.5 0.39 10.7 10.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) LRR_4 PF12799.7 KXS11667.1 - 0.00034 20.9 3.6 0.016 15.6 0.1 2.3 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) NDUF_C2 PF06374.11 KXS11668.1 - 5e-05 23.4 0.0 5.9e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2) DUF2182 PF09948.9 KXS11668.1 - 0.0089 15.9 0.0 0.0096 15.8 0.0 1.0 1 0 0 1 1 1 1 Predicted metal-binding integral membrane protein (DUF2182) FAT PF02259.23 KXS11669.1 - 1.8e-66 224.7 8.8 1.8e-66 224.7 8.8 2.1 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.27 KXS11669.1 - 1.1e-28 100.7 0.0 3.1e-28 99.2 0.0 1.8 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 KXS11669.1 - 1.2e-07 31.4 0.3 3.5e-07 29.9 0.3 1.9 1 0 0 1 1 1 1 FATC domain DUF1539 PF07560.11 KXS11669.1 - 0.0027 17.8 0.5 2 8.5 0.0 4.5 3 0 0 3 3 3 1 Domain of Unknown Function (DUF1539) Tubulin PF00091.25 KXS11670.1 - 1.5e-46 159.1 0.0 3.8e-40 138.2 0.0 2.2 2 0 0 2 2 2 2 Tubulin/FtsZ family, GTPase domain Tubulin_2 PF13809.6 KXS11670.1 - 0.00019 20.8 0.0 0.00029 20.1 0.0 1.2 1 0 0 1 1 1 1 Tubulin like HTH_Tnp_ISL3 PF13542.6 KXS11670.1 - 0.019 14.4 0.1 0.053 12.9 0.1 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 RRM_1 PF00076.22 KXS11671.1 - 1.1e-05 25.2 0.1 2.1e-05 24.2 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 KXS11672.1 - 8.5e-06 25.5 0.1 0.00086 19.1 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KXS11672.1 - 0.00013 21.9 0.1 0.00047 20.1 0.0 2.0 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 KXS11672.1 - 0.0069 16.4 0.1 0.039 14.0 0.0 2.2 2 0 0 2 2 2 1 RNA binding motif Pan3_PK PF18101.1 KXS11673.1 - 1.6e-60 203.1 0.1 3.8e-60 201.8 0.1 1.7 1 0 0 1 1 1 1 Pan3 Pseudokinase domain Pkinase PF00069.25 KXS11673.1 - 3.1e-05 23.5 0.0 5.1e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain HIGH_NTase1 PF05636.11 KXS11673.1 - 0.015 14.5 0.0 0.023 13.9 0.0 1.2 1 0 0 1 1 1 0 HIGH Nucleotidyl Transferase Pkinase_Tyr PF07714.17 KXS11673.1 - 0.048 12.9 0.0 0.081 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Phi_1 PF04674.12 KXS11676.1 - 1.7e-25 89.9 0.1 4.5e-21 75.4 0.0 2.2 1 1 1 2 2 2 2 Phosphate-induced protein 1 conserved region LRR_4 PF12799.7 KXS11676.1 - 0.19 12.2 2.1 2.4 8.7 1.3 3.1 2 1 2 4 4 4 0 Leucine Rich repeats (2 copies) DUF3265 PF11665.8 KXS11676.1 - 1.8 8.8 4.8 0.36 11.1 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3265) Sec8_exocyst PF04048.14 KXS11677.1 - 4.8e-33 114.0 1.1 1.2e-32 112.7 1.1 1.8 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain Vps54_N PF10475.9 KXS11677.1 - 0.0015 17.9 3.5 0.0047 16.3 3.5 1.8 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex DUF2451 PF10474.9 KXS11677.1 - 0.0035 17.2 0.1 0.014 15.2 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function C-terminus (DUF2451) DUF948 PF06103.11 KXS11677.1 - 0.59 10.4 3.7 12 6.2 0.1 3.6 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF948) DUF2306 PF10067.9 KXS11679.1 - 0.0013 19.0 12.9 0.0037 17.5 12.9 1.8 1 1 1 2 2 2 1 Predicted membrane protein (DUF2306) LapA_dom PF06305.11 KXS11679.1 - 0.31 10.9 3.0 0.36 10.7 0.1 2.5 2 1 0 2 2 2 0 Lipopolysaccharide assembly protein A domain LIM PF00412.22 KXS11681.1 - 6.7e-27 93.5 15.8 5.8e-10 39.2 0.9 4.2 3 1 0 4 4 4 3 LIM domain DEC-1_N PF04625.13 KXS11682.1 - 1.3 7.9 3.0 1.7 7.6 3.0 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region HNH_5 PF14279.6 KXS11683.1 - 0.56 10.1 4.5 9.5 6.2 0.0 2.3 2 0 0 2 2 2 0 HNH endonuclease Pkinase PF00069.25 KXS11684.1 - 5.2e-09 35.8 0.0 6.5e-09 35.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS11684.1 - 0.0004 19.8 0.0 0.00048 19.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KXS11684.1 - 0.054 12.4 0.0 0.075 12.0 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain SH3_9 PF14604.6 KXS11685.1 - 0.00014 21.6 0.0 0.0003 20.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXS11685.1 - 0.0068 16.0 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 SH3 domain zf-MYND PF01753.18 KXS11686.1 - 5.6e-10 39.2 9.6 5.6e-10 39.2 9.6 1.6 2 0 0 2 2 2 1 MYND finger zf-C6H2 PF15801.5 KXS11686.1 - 0.18 12.1 6.7 0.36 11.2 6.7 1.5 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding zf-Mss51 PF13824.6 KXS11686.1 - 0.4 10.8 3.3 0.88 9.7 3.3 1.5 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-RING_2 PF13639.6 KXS11687.1 - 1.1e-11 44.9 4.5 1.1e-11 44.9 4.5 1.7 2 0 0 2 2 1 1 Ring finger domain zf-RING_11 PF17123.5 KXS11687.1 - 2.6e-08 33.5 0.5 5.5e-08 32.4 0.5 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KXS11687.1 - 4e-08 32.9 4.2 4e-08 32.9 4.2 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXS11687.1 - 3.7e-07 30.1 0.5 3.7e-07 30.1 0.5 2.4 2 1 1 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KXS11687.1 - 1.8e-06 27.7 0.9 1.8e-06 27.7 0.9 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KXS11687.1 - 6e-06 26.4 5.1 1.5e-05 25.2 5.2 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KXS11687.1 - 0.00019 21.3 0.6 0.00019 21.3 0.6 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KXS11687.1 - 0.00037 20.3 1.1 0.00037 20.3 1.1 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KXS11687.1 - 0.0014 18.6 1.0 0.0035 17.3 1.0 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 KXS11687.1 - 0.006 16.7 2.9 0.006 16.7 2.9 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 KXS11687.1 - 0.011 15.5 1.3 0.019 14.7 1.3 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 KXS11687.1 - 0.032 14.1 3.0 0.11 12.3 3.0 1.9 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3H2C3 PF17122.5 KXS11687.1 - 0.12 12.5 2.9 0.28 11.3 2.9 1.7 1 1 0 1 1 1 0 Zinc-finger PHD PF00628.29 KXS11687.1 - 0.24 11.3 1.5 0.62 10.0 1.5 1.8 1 1 0 1 1 1 0 PHD-finger FANCL_C PF11793.8 KXS11687.1 - 0.29 11.3 4.3 2.3 8.4 3.8 2.6 2 1 0 2 2 1 0 FANCL C-terminal domain zinc_ribbon_16 PF17034.5 KXS11687.1 - 0.31 11.3 2.1 0.43 10.8 0.5 2.0 2 0 0 2 2 2 0 Zinc-ribbon like family Amidohydro_2 PF04909.14 KXS11689.1 - 4.9e-29 102.0 0.6 4.3e-28 98.9 0.6 1.9 1 1 0 1 1 1 1 Amidohydrolase VHP PF02209.19 KXS11690.1 - 3.3e-12 46.3 0.7 1.3e-11 44.3 1.0 1.9 2 0 0 2 2 2 1 Villin headpiece domain Gelsolin PF00626.22 KXS11690.1 - 2e-07 30.8 0.0 7.3e-07 29.0 0.0 1.9 2 0 0 2 2 2 1 Gelsolin repeat Pox_A_type_inc PF04508.12 KXS11691.1 - 0.05 13.5 0.0 0.15 12.0 0.0 1.8 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat KLRAQ PF10205.9 KXS11691.1 - 0.15 12.3 1.6 0.16 12.2 0.4 1.6 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein DivIVA PF05103.13 KXS11691.1 - 2.4 8.3 5.3 4.1 7.5 0.8 2.1 1 1 1 2 2 2 0 DivIVA protein DSPc PF00782.20 KXS11692.1 - 2.2e-19 69.6 0.0 2.6e-19 69.4 0.0 1.0 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KXS11692.1 - 0.27 10.8 0.0 0.3 10.6 0.0 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase GATA PF00320.27 KXS11693.1 - 1.4e-05 24.6 2.5 3.1e-05 23.5 2.5 1.6 1 0 0 1 1 1 1 GATA zinc finger FAA_hydrolase PF01557.18 KXS11694.1 - 1.5e-60 204.5 0.0 1.8e-60 204.3 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family SH3_9 PF14604.6 KXS11695.1 - 0.0012 18.7 0.0 0.002 17.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Herpes_gE PF02480.16 KXS11695.1 - 0.0022 16.8 0.0 0.0034 16.2 0.0 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Lustrin_cystein PF14625.6 KXS11695.1 - 0.014 15.7 4.7 0.031 14.6 4.7 1.5 1 0 0 1 1 1 0 Lustrin, cysteine-rich repeated domain SH3_1 PF00018.28 KXS11695.1 - 0.02 14.5 0.0 0.033 13.8 0.0 1.4 1 0 0 1 1 1 0 SH3 domain stn_TNFRSF12A PF12191.8 KXS11695.1 - 0.05 13.8 0.1 0.14 12.3 0.0 1.8 2 0 0 2 2 2 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain MGC-24 PF05283.11 KXS11695.1 - 6.2 7.3 9.9 0.11 13.0 1.4 2.3 2 1 1 3 3 3 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin SH3_9 PF14604.6 KXS11696.1 - 0.0011 18.7 0.1 0.0077 16.1 0.0 2.4 3 0 0 3 3 3 1 Variant SH3 domain SH3_1 PF00018.28 KXS11696.1 - 0.0046 16.5 0.1 0.011 15.3 0.1 1.6 1 0 0 1 1 1 1 SH3 domain Acyl-CoA_dh_1 PF00441.24 KXS11698.1 - 3.8e-45 153.8 2.8 5.5e-45 153.2 2.8 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KXS11698.1 - 6.3e-27 94.5 0.0 1.3e-26 93.5 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KXS11698.1 - 6.6e-22 78.2 0.1 1e-21 77.6 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KXS11698.1 - 1.8e-21 76.1 0.1 3.4e-21 75.2 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain OTU PF02338.19 KXS11699.1 - 7.9e-13 49.0 0.1 2.3e-12 47.5 0.0 1.7 2 0 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 KXS11699.1 - 0.0067 15.9 0.1 2.7 7.4 0.1 2.2 1 1 1 2 2 2 2 Peptidase C65 Otubain NAD_binding_10 PF13460.6 KXS11700.1 - 1.2e-06 28.6 1.7 1.1e-05 25.4 1.5 2.4 2 1 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 KXS11700.1 - 1.4e-06 28.0 0.0 7.3e-06 25.6 0.1 1.9 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXS11700.1 - 3.3e-06 26.3 0.2 8.9e-05 21.6 0.0 2.4 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KXS11700.1 - 5.1e-05 22.6 0.2 0.089 11.9 0.0 2.5 2 1 0 2 2 2 2 Male sterility protein NmrA PF05368.13 KXS11700.1 - 0.006 16.2 0.3 0.006 16.2 0.3 1.6 2 0 0 2 2 2 1 NmrA-like family GDP_Man_Dehyd PF16363.5 KXS11700.1 - 0.014 14.8 0.0 0.018 14.4 0.0 1.1 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase 2-Hacid_dh_C PF02826.19 KXS11700.1 - 0.14 11.5 1.5 0.29 10.5 0.0 2.1 2 1 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Ank_5 PF13857.6 KXS11701.1 - 3.7e-07 30.3 0.7 1.4 9.3 0.0 4.2 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXS11701.1 - 1.2e-06 28.4 0.1 0.2 12.3 0.0 5.3 7 0 0 7 7 7 2 Ankyrin repeat Ank_2 PF12796.7 KXS11701.1 - 1.2e-06 29.0 0.2 0.34 11.5 0.0 3.9 3 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 KXS11701.1 - 2.2e-05 24.7 1.1 11 6.7 0.0 5.0 5 0 0 5 5 5 2 Ankyrin repeat SH3_9 PF14604.6 KXS11701.1 - 0.0035 17.2 0.0 0.0089 15.9 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain Dynamitin PF04912.14 KXS11701.1 - 0.021 14.2 2.3 0.029 13.7 2.3 1.1 1 0 0 1 1 1 0 Dynamitin FH2 PF02181.23 KXS11701.1 - 0.055 12.6 0.1 0.23 10.6 0.0 1.7 1 1 1 2 2 2 0 Formin Homology 2 Domain SH3_1 PF00018.28 KXS11701.1 - 0.061 12.9 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 SH3 domain MFS_1 PF07690.16 KXS11702.1 - 3.8e-27 95.1 32.5 3.8e-27 95.1 32.5 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Cation_ATPase_C PF00689.21 KXS11703.1 - 3.2e-24 85.7 9.8 3.2e-24 85.7 9.8 3.3 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KXS11703.1 - 8.6e-22 77.5 1.9 8.6e-22 77.5 1.9 2.4 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 KXS11703.1 - 5.5e-15 56.2 0.0 7.5e-08 32.9 0.0 2.6 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KXS11703.1 - 2.9e-14 52.9 0.0 6.2e-14 51.9 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KXS11703.1 - 4.8e-08 32.6 0.0 1.2e-07 31.3 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus DUF2798 PF11391.8 KXS11704.1 - 0.27 11.3 4.6 2.8 8.0 1.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2798) UreF PF01730.16 KXS11704.1 - 0.75 10.4 6.6 0.79 10.3 6.3 1.3 1 1 0 1 1 1 0 UreF FGGY_C PF02782.16 KXS11705.1 - 1.3e-35 123.0 0.2 2e-35 122.3 0.2 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 KXS11705.1 - 1.2e-23 84.0 0.0 1.3e-21 77.3 0.0 2.2 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.20 KXS11705.1 - 1.4e-06 28.0 0.1 0.0074 15.8 0.0 2.4 2 0 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family DEDD_Tnp_IS110 PF01548.17 KXS11705.1 - 0.059 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Transposase Hexokinase_1 PF00349.21 KXS11705.1 - 0.18 11.7 0.0 0.28 11.0 0.0 1.2 1 0 0 1 1 1 0 Hexokinase Abhydrolase_3 PF07859.13 KXS11707.1 - 1.4e-33 116.5 0.0 1.9e-33 116.2 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KXS11707.1 - 1.6e-07 30.5 0.0 2.1e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Thiolase_N PF00108.23 KXS11708.1 - 3.4e-77 259.3 3.6 3.4e-77 259.3 3.6 1.5 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KXS11708.1 - 6.7e-48 161.4 0.8 6.7e-48 161.4 0.8 2.0 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KXS11708.1 - 0.00064 19.4 3.1 0.0049 16.5 1.4 2.5 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KXS11708.1 - 0.06 13.2 0.9 15 5.5 0.0 2.7 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Beta-lactamase2 PF13354.6 KXS11708.1 - 0.072 12.7 0.1 5.8 6.5 0.1 2.8 1 1 1 2 2 2 0 Beta-lactamase enzyme family ACP_syn_III_C PF08541.10 KXS11708.1 - 0.075 13.2 0.1 0.33 11.1 0.0 2.2 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Polysacc_deac_1 PF01522.21 KXS11709.1 - 6.2e-23 81.0 0.0 9.7e-23 80.4 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 KXS11709.1 - 2.3e-06 27.4 1.8 2e-05 24.3 1.8 2.2 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) DUF727 PF05303.12 KXS11709.1 - 0.014 15.5 0.0 0.031 14.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF727) PhyH PF05721.13 KXS11712.1 - 1.2e-11 45.2 0.0 1.6e-11 44.9 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) SIT PF15330.6 KXS11712.1 - 0.065 13.7 0.0 0.098 13.1 0.0 1.3 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT Gpr1_Fun34_YaaH PF01184.19 KXS11714.1 - 1e-14 54.7 14.3 1.3e-14 54.3 14.3 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF2070 PF09843.9 KXS11714.1 - 7.7 4.7 9.3 10 4.3 9.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Pkinase_Tyr PF07714.17 KXS11715.1 - 6.1e-07 29.0 0.0 7.2e-07 28.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXS11715.1 - 2.1e-05 24.0 0.0 2.6e-05 23.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain DUF2333 PF10095.9 KXS11717.1 - 0.04 12.9 0.1 0.04 12.9 0.1 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2333) SCO1-SenC PF02630.14 KXS11717.1 - 0.075 12.9 0.1 0.21 11.5 0.0 1.8 2 0 0 2 2 2 0 SCO1/SenC SOBP PF15279.6 KXS11717.1 - 1.2 9.7 5.3 1.7 9.2 5.3 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein DDE_Tnp_4 PF13359.6 KXS11718.1 - 8.4e-07 28.8 0.0 9.7e-07 28.6 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Peptidase_C25 PF01364.18 KXS11718.1 - 0.00067 19.0 0.0 0.00078 18.7 0.0 1.0 1 0 0 1 1 1 1 Peptidase family C25 Sel1 PF08238.12 KXS11719.1 - 6.9e-32 109.2 3.1 3.9e-07 30.5 0.1 4.2 4 0 0 4 4 4 4 Sel1 repeat Pkinase_Tyr PF07714.17 KXS11719.1 - 0.00091 18.6 0.1 0.0014 18.0 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Mannosyl_trans3 PF11051.8 KXS11721.1 - 2.8e-41 141.7 0.0 4.8e-41 140.9 0.0 1.4 1 1 0 1 1 1 1 Mannosyltransferase putative Sel1 PF08238.12 KXS11722.1 - 2.6e-23 81.9 7.8 1.2e-05 25.8 0.7 4.5 4 0 0 4 4 4 4 Sel1 repeat Pkinase_Tyr PF07714.17 KXS11722.1 - 0.0024 17.2 0.1 0.0041 16.4 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase zf-C3HC4_3 PF13920.6 KXS11722.1 - 0.0027 17.5 2.4 0.0027 17.5 2.4 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KXS11722.1 - 0.0074 16.1 3.4 0.0074 16.1 3.4 1.8 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KXS11722.1 - 0.011 15.6 4.0 0.011 15.6 4.0 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXS11722.1 - 0.022 14.6 4.9 0.054 13.4 4.9 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXS11722.1 - 4.9 7.6 9.5 0.55 10.6 3.8 2.2 2 0 0 2 2 2 0 Ring finger domain PX PF00787.24 KXS11723.1 - 1.2e-13 51.0 0.0 2.1e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 PX domain cNMP_binding PF00027.29 KXS11724.1 - 3.2e-20 72.0 0.1 8.8e-20 70.6 0.0 1.8 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain NUDIX PF00293.28 KXS11726.1 - 3.4e-19 69.2 5.1 4e-19 69.0 5.1 1.1 1 0 0 1 1 1 1 NUDIX domain Choline_transpo PF04515.12 KXS11728.1 - 1.5e-75 254.4 28.7 1.5e-75 254.4 28.7 2.0 2 0 0 2 2 2 1 Plasma-membrane choline transporter PRIMA1 PF16101.5 KXS11728.1 - 0.63 10.1 1.7 3 7.9 0.1 2.5 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 hDGE_amylase PF14701.6 KXS11729.1 - 5.2e-147 490.5 0.0 7.2e-147 490.0 0.0 1.1 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain GDE_C PF06202.14 KXS11729.1 - 8.5e-111 370.6 0.0 4.2e-110 368.3 0.0 1.8 2 0 0 2 2 2 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.6 KXS11729.1 - 1.1e-64 218.5 0.0 2e-64 217.7 0.0 1.4 1 0 0 1 1 1 1 Central domain of human glycogen debranching enzyme hGDE_N PF14699.6 KXS11729.1 - 1.5e-12 47.4 0.0 3.7e-12 46.2 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.24 KXS11729.1 - 0.087 12.4 0.0 1.4 8.4 0.0 2.1 2 0 0 2 2 2 0 Alpha amylase, catalytic domain PP2C PF00481.21 KXS11730.1 - 0.033 13.8 0.0 0.42 10.2 0.0 2.3 2 0 0 2 2 2 0 Protein phosphatase 2C CAMSAP_CKK PF08683.11 KXS11731.1 - 1.5e-19 70.3 0.0 2.9e-19 69.4 0.0 1.5 1 0 0 1 1 1 1 Microtubule-binding calmodulin-regulated spectrin-associated CH_2 PF06294.11 KXS11731.1 - 0.0079 16.3 0.0 0.016 15.3 0.0 1.5 1 0 0 1 1 1 1 CH-like domain in sperm protein PIG-L PF02585.17 KXS11732.1 - 4.8e-18 66.0 0.0 9.6e-18 65.1 0.0 1.5 1 1 0 1 1 1 1 GlcNAc-PI de-N-acetylase tRNA_bind PF01588.20 KXS11733.1 - 1.2e-14 54.2 0.0 1.5e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 Putative tRNA binding domain F-box PF00646.33 KXS11735.1 - 0.0033 17.3 0.4 0.029 14.3 0.5 2.5 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.7 KXS11735.1 - 0.022 14.7 0.6 0.061 13.2 0.6 1.8 1 0 0 1 1 1 0 F-box-like CPSase_L_D2 PF02786.17 KXS11738.1 - 1.6e-74 250.0 0.0 3.2e-74 249.0 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 KXS11738.1 - 1.6e-68 230.4 0.0 2.4e-68 229.8 0.0 1.3 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_carb_N PF00289.22 KXS11738.1 - 1.3e-38 132.0 0.2 2.9e-38 130.8 0.2 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KXS11738.1 - 4.4e-32 110.4 0.0 2.9e-31 107.8 0.0 2.2 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.19 KXS11738.1 - 2.5e-26 92.8 0.0 5.1e-26 91.8 0.0 1.5 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.22 KXS11738.1 - 4.7e-14 52.0 2.1 9.7e-14 51.0 2.1 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 KXS11738.1 - 2.7e-08 33.6 0.0 5.4e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.6 KXS11738.1 - 5.4e-08 32.5 2.9 0.0022 17.8 0.5 2.5 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp PF02222.22 KXS11738.1 - 2.7e-07 30.3 0.0 5.7e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 KXS11738.1 - 1e-05 25.7 0.0 2.3e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.6 KXS11738.1 - 9.8e-05 23.0 2.4 0.09 13.5 0.4 3.2 3 1 1 4 4 2 2 HlyD family secretion protein Amidohydro_2 PF04909.14 KXS11738.1 - 0.0023 17.8 0.2 1.3 8.7 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase ATPgrasp_Ter PF15632.6 KXS11738.1 - 0.0027 17.4 0.4 0.082 12.7 0.0 2.7 3 0 0 3 3 3 1 ATP-grasp in the biosynthetic pathway with Ter operon HlyD_D23 PF16576.5 KXS11738.1 - 0.0053 16.0 0.2 0.087 12.0 0.1 2.2 1 1 1 2 2 2 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion Helicase_C PF00271.31 KXS11739.1 - 4.4e-18 65.6 0.0 8.1e-18 64.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 KXS11739.1 - 9e-16 57.5 0.0 1.3e-15 57.0 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain ERCC3_RAD25_C PF16203.5 KXS11739.1 - 0.0017 17.6 0.0 0.0026 17.0 0.0 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase SNF2_N PF00176.23 KXS11740.1 - 3.4e-18 65.5 0.0 5.7e-18 64.7 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 KXS11740.1 - 0.0092 16.0 0.0 0.029 14.4 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Methyltransf_23 PF13489.6 KXS11741.1 - 3e-17 63.0 0.0 4.3e-17 62.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXS11741.1 - 2.3e-16 60.2 0.1 3.6e-16 59.6 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXS11741.1 - 1.2e-14 54.3 0.0 2.4e-14 53.4 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXS11741.1 - 9.9e-14 51.8 0.2 1.8e-13 51.0 0.2 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXS11741.1 - 4.9e-11 43.2 0.1 8.4e-11 42.5 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KXS11741.1 - 1.8e-09 37.3 0.0 3.1e-09 36.5 0.0 1.3 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.13 KXS11741.1 - 3.2e-07 30.0 0.0 4.6e-07 29.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 KXS11741.1 - 1.1e-05 25.5 0.0 1.7e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXS11741.1 - 0.0016 18.0 0.0 0.0024 17.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain TPMT PF05724.11 KXS11741.1 - 0.0018 18.0 0.0 0.0024 17.5 0.0 1.2 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_9 PF08003.11 KXS11741.1 - 0.0021 17.1 0.0 0.0032 16.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Ubie_methyltran PF01209.18 KXS11741.1 - 0.0025 17.2 0.0 0.013 14.9 0.0 1.8 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family MetW PF07021.12 KXS11741.1 - 0.011 15.4 0.2 0.019 14.5 0.2 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW PCMT PF01135.19 KXS11741.1 - 0.021 14.6 0.1 0.035 13.9 0.1 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) NodS PF05401.11 KXS11741.1 - 0.039 13.6 0.0 0.069 12.8 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) Cons_hypoth95 PF03602.15 KXS11741.1 - 0.039 13.6 0.0 0.065 12.9 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 CoA_transf_3 PF02515.17 KXS11741.1 - 0.067 12.3 0.4 0.1 11.7 0.4 1.2 1 0 0 1 1 1 0 CoA-transferase family III Ribosomal_L34e PF01199.18 KXS11742.1 - 6.2e-45 151.4 3.0 8.8e-45 151.0 3.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L34e FhuF_C PF11575.8 KXS11742.1 - 0.57 10.2 4.1 3.4 7.7 0.2 2.5 2 0 0 2 2 2 0 FhuF 2Fe-2S C-terminal domain Phosphodiest PF01663.22 KXS11744.1 - 4.3e-15 56.2 0.0 1.4e-13 51.2 0.0 2.5 1 1 1 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KXS11744.1 - 0.0025 17.2 0.0 0.0049 16.3 0.0 1.5 1 0 0 1 1 1 1 Sulfatase Ub-Mut7C PF14451.6 KXS11744.1 - 0.19 11.6 0.0 0.45 10.4 0.0 1.6 1 0 0 1 1 1 0 Mut7-C ubiquitin Acetyltransf_1 PF00583.25 KXS11745.1 - 1.3e-10 41.5 0.0 1.6e-10 41.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXS11745.1 - 3.8e-10 40.1 0.0 5.1e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KXS11745.1 - 5e-09 36.2 0.0 7e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXS11745.1 - 4.1e-05 23.5 0.0 6.1e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_13 PF13880.6 KXS11745.1 - 0.00032 20.6 0.0 0.00051 20.0 0.0 1.2 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase Acetyltransf_15 PF17013.5 KXS11745.1 - 0.0011 18.5 0.0 0.0043 16.5 0.0 1.8 1 1 0 1 1 1 1 Putative acetyl-transferase Acetyltransf_3 PF13302.7 KXS11745.1 - 0.0071 17.0 0.0 0.0075 17.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KXS11745.1 - 0.061 13.5 0.0 0.071 13.2 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KXS11745.1 - 0.15 12.2 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Ribosomal_L34e PF01199.18 KXS11746.1 - 5.8e-45 151.5 2.5 8.1e-45 151.1 2.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L34e Gpr1_Fun34_YaaH PF01184.19 KXS11747.1 - 3.7e-18 65.9 20.6 4.6e-18 65.6 20.6 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DDDD PF10161.9 KXS11747.1 - 8.6 6.2 6.5 20 5.1 0.3 2.7 2 1 0 2 2 2 0 Putative mitochondrial precursor protein SKA1 PF07160.12 KXS11749.1 - 0.014 15.3 0.0 0.026 14.4 0.0 1.3 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 Peptidase_C14 PF00656.22 KXS11750.1 - 2.9e-23 83.1 0.0 3.9e-23 82.7 0.0 1.1 1 0 0 1 1 1 1 Caspase domain ANAPC4_WD40 PF12894.7 KXS11752.1 - 1.6e-05 25.1 0.0 0.073 13.4 0.0 3.3 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KXS11752.1 - 3.7e-05 24.4 6.7 0.024 15.5 0.0 4.1 4 1 0 4 4 4 2 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 KXS11752.1 - 0.028 13.5 0.0 3 6.8 0.0 2.4 2 0 0 2 2 2 0 Coatomer WD associated region Sterol_MT_C PF08498.10 KXS11753.1 - 5e-23 81.2 0.2 8.2e-23 80.5 0.2 1.4 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 KXS11753.1 - 3.4e-21 75.7 0.0 5.7e-21 75.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXS11753.1 - 7e-18 64.9 0.0 1e-17 64.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXS11753.1 - 1.1e-16 61.3 0.0 1.9e-16 60.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXS11753.1 - 5.7e-14 52.3 0.0 8.4e-14 51.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KXS11753.1 - 1.2e-13 51.0 0.0 1.6e-13 50.6 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 KXS11753.1 - 3.3e-09 36.4 0.0 5.6e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KXS11753.1 - 1.2e-08 35.6 0.0 2.4e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 KXS11753.1 - 1.2e-05 25.0 0.0 1.9e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW PCMT PF01135.19 KXS11753.1 - 0.0029 17.4 0.0 0.0067 16.2 0.0 1.5 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_9 PF08003.11 KXS11753.1 - 0.13 11.2 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) MTS PF05175.14 KXS11753.1 - 0.14 11.7 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_15 PF09445.10 KXS11753.1 - 0.14 11.7 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase RrnaAD PF00398.20 KXS11753.1 - 0.16 11.0 0.0 0.23 10.5 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Pyr_redox_2 PF07992.14 KXS11754.1 - 3e-40 138.3 0.1 3.7e-40 138.0 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.26 KXS11754.1 - 1.1e-10 41.3 0.0 2.1e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox PF00070.27 KXS11754.1 - 5.6e-08 33.2 1.0 0.00014 22.4 0.1 3.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXS11754.1 - 0.0016 17.8 0.1 0.94 8.7 0.0 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KXS11754.1 - 0.0053 15.6 0.3 0.31 9.9 0.1 2.4 2 1 1 3 3 3 2 Tryptophan halogenase Annexin PF00191.20 KXS11756.1 - 7.1e-34 115.7 0.0 3.5e-13 49.4 0.0 3.8 4 0 0 4 4 4 3 Annexin AMPK1_CBM PF16561.5 KXS11756.1 - 7.8e-26 90.1 0.0 9.1e-12 45.0 0.0 2.4 2 0 0 2 2 2 2 Glycogen recognition site of AMP-activated protein kinase CBM_20 PF00686.19 KXS11756.1 - 0.019 14.8 0.0 3.5 7.6 0.0 2.4 2 0 0 2 2 2 0 Starch binding domain Glyco_hydro_26 PF02156.15 KXS11757.1 - 4.5e-09 36.2 0.7 1.3e-06 28.1 0.7 2.2 1 1 0 1 1 1 1 Glycosyl hydrolase family 26 SOG2 PF10428.9 KXS11757.1 - 1.8 7.7 10.2 2.3 7.3 10.2 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Complex1_51K PF01512.17 KXS11759.1 - 1.7e-49 167.6 0.0 2.5e-49 167.1 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 KXS11759.1 - 4.5e-31 106.8 0.3 1.2e-30 105.4 0.1 1.9 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 KXS11759.1 - 3.9e-09 36.2 0.0 7.2e-09 35.4 0.0 1.5 1 0 0 1 1 1 1 SLBB domain Aldedh PF00171.22 KXS11760.1 - 2.7e-99 332.8 0.0 3.6e-99 332.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DMAP1_like PF17024.5 KXS11760.1 - 0.043 13.9 0.6 0.08 13.1 0.6 1.4 1 0 0 1 1 1 0 Putative DMAP1-like ThaI PF15514.6 KXS11760.1 - 0.055 13.1 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Restriction endonuclease ThaI Pkinase PF00069.25 KXS11762.1 - 3.3e-70 236.5 0.0 4.1e-70 236.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS11762.1 - 1.3e-34 119.7 0.0 1.8e-34 119.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KXS11762.1 - 0.00067 19.1 0.3 0.0011 18.4 0.3 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KXS11762.1 - 0.00074 18.6 0.0 0.0013 17.7 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KXS11762.1 - 0.044 13.7 0.6 0.13 12.2 0.1 2.0 2 1 1 3 3 3 0 Phosphotransferase enzyme family Kinase-like PF14531.6 KXS11762.1 - 0.12 11.7 0.0 3.7 6.8 0.0 2.2 1 1 0 2 2 2 0 Kinase-like DIE2_ALG10 PF04922.12 KXS11763.1 - 2.5e-107 359.6 17.7 3.5e-107 359.1 17.7 1.2 1 0 0 1 1 1 1 DIE2/ALG10 family FA_hydroxylase PF04116.13 KXS11764.1 - 1.1e-23 84.0 14.3 1.6e-23 83.5 14.3 1.2 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily Polysacc_deac_1 PF01522.21 KXS11765.1 - 1.1e-15 57.6 0.0 2.4e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase FA_hydroxylase PF04116.13 KXS11766.1 - 3.5e-25 88.9 20.6 7.6e-25 87.8 20.6 1.6 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily zf-Tim10_DDP PF02953.15 KXS11767.1 - 1.3e-24 85.7 0.1 1.5e-24 85.4 0.1 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.13 KXS11767.1 - 0.0087 15.8 1.7 0.042 13.5 1.7 1.8 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) LRR_6 PF13516.6 KXS11769.1 - 0.00064 19.6 0.9 0.012 15.6 0.0 3.0 3 0 0 3 3 3 1 Leucine Rich repeat LRR_4 PF12799.7 KXS11769.1 - 0.08 13.4 1.2 0.38 11.3 1.4 2.0 1 1 0 1 1 1 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXS11769.1 - 0.14 12.0 0.8 0.77 9.6 0.0 2.3 2 0 0 2 2 2 0 Leucine rich repeat Pkinase_Tyr PF07714.17 KXS11770.1 - 4.9e-21 75.2 0.0 5.2e-21 75.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXS11770.1 - 3.2e-17 62.8 0.0 3.4e-17 62.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KXS11770.1 - 8.2e-05 22.0 0.0 8.3e-05 22.0 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KXS11770.1 - 0.00021 20.9 0.0 0.00023 20.8 0.0 1.0 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 KXS11770.1 - 0.0018 18.2 0.0 0.0018 18.2 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KXS11770.1 - 0.0032 16.5 0.0 0.0033 16.4 0.0 1.0 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KXS11770.1 - 0.036 13.4 0.0 0.042 13.2 0.0 1.1 1 0 0 1 1 1 0 Kinase-like Choline_kinase PF01633.20 KXS11770.1 - 0.17 11.4 0.0 0.45 10.1 0.0 1.6 1 1 1 2 2 2 0 Choline/ethanolamine kinase CS PF04969.16 KXS11771.1 - 2.4e-18 66.9 0.1 5.2e-18 65.8 0.0 1.6 2 0 0 2 2 2 1 CS domain Nbs1_C PF08599.10 KXS11771.1 - 3.2 8.0 5.4 23 5.2 0.1 2.7 2 0 0 2 2 2 0 DNA damage repair protein Nbs1 HTH_AraC PF00165.23 KXS11777.1 - 0.036 14.2 0.9 0.057 13.6 0.1 1.7 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix proteins, AraC family TusA PF01206.17 KXS11777.1 - 0.062 13.1 0.0 0.15 11.9 0.0 1.6 2 0 0 2 2 2 0 Sulfurtransferase TusA UPF0004 PF00919.20 KXS11779.1 - 1.1e-16 60.6 0.0 2.4e-16 59.6 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 Radical_SAM PF04055.21 KXS11779.1 - 1e-11 45.5 0.0 2.2e-11 44.4 0.0 1.6 1 0 0 1 1 1 1 Radical SAM superfamily F-box-like PF12937.7 KXS11781.1 - 1.7e-09 37.4 0.2 2.8e-09 36.7 0.2 1.3 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXS11781.1 - 3.8e-07 29.8 0.1 6.2e-07 29.2 0.1 1.3 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KXS11781.1 - 0.02 14.8 0.0 0.026 14.4 0.0 1.3 1 0 0 1 1 1 0 F-box Rad21_Rec8 PF04824.16 KXS11781.1 - 0.17 11.2 0.0 0.31 10.3 0.0 1.4 1 0 0 1 1 1 0 Conserved region of Rad21 / Rec8 like protein Thymidylate_kin PF02223.17 KXS11783.1 - 6.7e-41 140.0 0.0 7.9e-41 139.8 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase AAA_18 PF13238.6 KXS11783.1 - 0.024 15.2 0.0 0.036 14.6 0.0 1.4 1 1 0 1 1 1 0 AAA domain KTI12 PF08433.10 KXS11783.1 - 0.042 13.3 0.0 0.15 11.5 0.0 1.7 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Secretin_N PF03958.17 KXS11783.1 - 0.11 12.9 0.0 13 6.3 0.0 2.7 2 1 1 3 3 3 0 Bacterial type II/III secretion system short domain AAA_16 PF13191.6 KXS11783.1 - 0.12 12.8 0.0 0.2 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Aldo_ket_red PF00248.21 KXS11784.1 - 6e-73 245.6 0.0 6.8e-73 245.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family MC1 PF05854.11 KXS11784.1 - 0.053 13.8 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 Non-histone chromosomal protein MC1 CCDC66 PF15236.6 KXS11786.1 - 7.3e-06 25.9 20.9 7.3e-06 25.9 20.9 3.6 4 0 0 4 4 4 2 Coiled-coil domain-containing protein 66 Borrelia_P83 PF05262.11 KXS11786.1 - 1.6e-05 23.6 4.1 1.6e-05 23.6 4.1 1.6 2 0 0 2 2 2 1 Borrelia P83/100 protein Sporozoite_P67 PF05642.11 KXS11786.1 - 1.9 6.5 8.9 2.2 6.2 3.5 2.3 2 0 0 2 2 2 0 Sporozoite P67 surface antigen F-box-like PF12937.7 KXS11787.1 - 1.9e-07 30.9 0.7 2.3e-07 30.6 0.1 1.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KXS11787.1 - 0.002 17.9 0.0 0.0039 17.0 0.0 1.5 2 0 0 2 2 2 1 F-box domain zf-PARP PF00645.18 KXS11789.1 - 5.3e-13 49.6 0.2 1.1e-12 48.6 0.0 1.6 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region DTHCT PF08070.11 KXS11789.1 - 0.049 14.4 17.9 0.069 13.9 17.5 1.5 1 1 0 1 1 1 0 DTHCT (NUC029) region Aldedh PF00171.22 KXS11790.1 - 1.1e-84 284.6 0.0 2.1e-84 283.7 0.0 1.4 1 1 0 1 1 1 1 Aldehyde dehydrogenase family Glycolytic PF00274.19 KXS11791.1 - 8.2e-174 577.3 0.0 9.3e-174 577.1 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I PE_PPE_C PF12484.8 KXS11791.1 - 1.8 9.6 6.4 18 6.4 0.0 2.9 2 1 0 2 2 2 0 Polymorphic PE/PPE proteins C terminal Lyase_1 PF00206.20 KXS11792.1 - 6.7e-118 393.6 0.0 8.8e-118 393.2 0.0 1.1 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 KXS11792.1 - 2.7e-26 91.7 0.1 5.8e-26 90.7 0.1 1.6 1 0 0 1 1 1 1 Fumarase C C-terminus G-alpha PF00503.20 KXS11792.1 - 0.2 10.8 0.0 0.32 10.1 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit MmgE_PrpD PF03972.14 KXS11793.1 - 4.7e-88 295.6 1.8 6e-88 295.3 1.8 1.0 1 0 0 1 1 1 1 MmgE/PrpD family LRR_6 PF13516.6 KXS11794.1 - 4.1e-33 110.6 30.1 3.4e-06 26.6 0.2 8.0 8 0 0 8 8 8 7 Leucine Rich repeat LRR_4 PF12799.7 KXS11794.1 - 1.9e-16 59.9 18.5 6.9e-06 26.3 0.8 4.5 2 1 2 5 5 5 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KXS11794.1 - 1.3e-12 46.4 5.6 0.17 12.5 0.0 6.4 7 0 0 7 7 7 4 Leucine Rich Repeat LRR_8 PF13855.6 KXS11794.1 - 5.2e-07 29.3 19.6 0.033 14.0 2.1 5.6 4 1 1 5 5 5 4 Leucine rich repeat LRR_2 PF07723.13 KXS11794.1 - 0.00041 20.9 0.0 3.7 8.4 0.0 5.1 6 0 0 6 6 6 1 Leucine Rich Repeat Bunya_NS-S PF01104.17 KXS11794.1 - 0.021 14.6 1.1 2.4 8.0 0.1 3.6 3 1 1 4 4 4 0 Bunyavirus non-structural protein NS-s Ribos_L4_asso_C PF14374.6 KXS11795.1 - 0.018 15.1 0.4 0.038 14.0 0.4 1.5 1 0 0 1 1 1 0 60S ribosomal protein L4 C-terminal domain Luciferase_N PF05295.11 KXS11795.1 - 0.087 12.8 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Luciferase/LBP N-terminal domain DOMON PF03351.17 KXS11797.1 - 2.2e-09 37.6 0.1 3.1e-09 37.1 0.1 1.2 1 0 0 1 1 1 1 DOMON domain CDH-cyt PF16010.5 KXS11797.1 - 2.8e-05 23.9 0.0 2.8e-05 23.9 0.0 1.6 2 0 0 2 2 2 1 Cytochrome domain of cellobiose dehydrogenase VSP PF03302.13 KXS11798.1 - 0.011 14.7 0.3 0.016 14.1 0.3 1.3 1 0 0 1 1 1 0 Giardia variant-specific surface protein SNARE_assoc PF09335.11 KXS11798.1 - 0.1 13.1 0.8 0.26 11.8 0.8 1.6 1 0 0 1 1 1 0 SNARE associated Golgi protein DUF2722 PF10846.8 KXS11799.1 - 0.02 13.9 0.7 0.023 13.7 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Pkinase PF00069.25 KXS11801.1 - 1.3e-15 57.5 0.0 2.1e-14 53.6 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS11801.1 - 5.9e-14 52.0 0.0 2.1e-08 33.8 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXS11802.1 - 1.8e-23 83.2 0.0 2.1e-23 83.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS11802.1 - 4e-18 65.6 0.0 4.9e-18 65.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Acid_phosphat_B PF03767.14 KXS11802.1 - 0.084 12.5 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) Sel1 PF08238.12 KXS11803.1 - 7e-41 137.7 9.1 2.2e-08 34.5 0.1 6.8 7 0 0 7 7 7 6 Sel1 repeat TPR_6 PF13174.6 KXS11803.1 - 0.043 14.5 0.3 13 6.7 0.0 3.3 4 1 0 4 4 4 0 Tetratricopeptide repeat SPO22 PF08631.10 KXS11803.1 - 0.078 12.5 0.4 0.63 9.5 0.0 2.4 2 1 1 3 3 3 0 Meiosis protein SPO22/ZIP4 like Fib_succ_major PF09603.10 KXS11803.1 - 0.17 12.5 7.6 6.7 7.3 0.6 3.7 1 1 1 2 2 2 0 Fibrobacter succinogenes major domain (Fib_succ_major) TPR_1 PF00515.28 KXS11803.1 - 0.34 10.8 9.2 17 5.4 0.0 6.0 8 0 0 8 8 8 0 Tetratricopeptide repeat Capsule_synth PF05159.14 KXS11803.1 - 0.45 9.9 0.9 53 3.1 0.1 3.2 2 1 2 4 4 4 0 Capsule polysaccharide biosynthesis protein SRP_TPR_like PF17004.5 KXS11805.1 - 1.7e-12 47.4 2.9 1.2e-10 41.5 1.6 2.7 2 1 1 3 3 3 1 Putative TPR-like repeat TPR_17 PF13431.6 KXS11805.1 - 1.6e-05 25.0 6.6 0.0056 17.0 0.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KXS11805.1 - 2.4e-05 24.1 15.8 0.19 11.9 0.4 6.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 KXS11805.1 - 0.00074 19.8 16.0 0.0087 16.3 3.3 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KXS11805.1 - 0.0078 16.4 8.2 0.073 13.3 0.4 3.8 2 2 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 KXS11805.1 - 0.0078 16.7 6.6 0.1 13.1 0.0 3.8 2 2 2 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 KXS11805.1 - 0.036 14.9 10.6 17 6.5 0.0 5.3 4 2 2 6 6 6 0 Tetratricopeptide repeat TPR_9 PF13371.6 KXS11805.1 - 0.062 13.5 2.8 4.9 7.4 0.0 3.3 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 KXS11805.1 - 0.081 12.8 14.8 5.1 7.1 0.1 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.6 KXS11805.1 - 0.1 12.9 11.5 8.2 6.9 0.1 5.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_4 PF07721.14 KXS11805.1 - 0.15 12.7 11.9 24 5.9 0.1 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat Acetyltransf_1 PF00583.25 KXS11809.1 - 0.00028 21.1 0.0 0.0015 18.7 0.0 2.2 2 1 0 2 2 2 1 Acetyltransferase (GNAT) family GvpO PF05800.11 KXS11809.1 - 0.052 13.5 0.6 0.1 12.6 0.6 1.5 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpO Ank_2 PF12796.7 KXS11811.1 - 2.9e-21 75.8 7.9 2e-09 37.9 0.1 4.5 1 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXS11811.1 - 7.9e-21 71.9 4.9 0.025 15.1 0.0 8.2 8 0 0 8 8 8 5 Ankyrin repeat Ank_4 PF13637.6 KXS11811.1 - 1.3e-15 57.5 7.3 0.00017 22.1 0.1 7.1 3 2 4 7 7 7 5 Ankyrin repeats (many copies) Ank PF00023.30 KXS11811.1 - 2.3e-15 56.2 17.5 0.087 13.3 0.3 7.7 7 1 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 KXS11811.1 - 2.5e-09 37.2 11.5 0.069 13.5 0.4 6.9 5 1 2 7 7 7 3 Ankyrin repeats (many copies) Fer2_2 PF01799.20 KXS11811.1 - 0.054 13.5 0.1 2.8 8.0 0.1 2.4 2 0 0 2 2 2 0 [2Fe-2S] binding domain FAM131 PF15010.6 KXS11812.1 - 0.11 12.4 0.0 0.25 11.2 0.0 1.6 2 0 0 2 2 2 0 Putative cell signalling MBG_2 PF18676.1 KXS11812.1 - 0.5 11.0 2.6 0.66 10.7 0.3 2.3 2 0 0 2 2 2 0 MBG domain (YGX type) MFS_1 PF07690.16 KXS11814.1 - 1.8e-41 142.3 13.9 1.8e-41 142.3 13.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXS11814.1 - 3.5e-08 32.7 0.5 3.5e-08 32.7 0.5 1.5 2 0 0 2 2 2 1 Sugar (and other) transporter Phage_holin_5_2 PF16079.5 KXS11815.1 - 0.11 12.8 0.9 0.2 12.0 0.9 1.4 1 0 0 1 1 1 0 Phage holin family Hol44, in holin superfamily V Phage_holin_3_6 PF07332.11 KXS11816.1 - 4.8 7.2 8.1 7.8 6.6 5.2 2.1 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III MscL PF01741.18 KXS11819.1 - 1.3e-23 83.6 0.2 1.7e-23 83.2 0.2 1.2 1 0 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL zf-ribbon_3 PF13248.6 KXS11819.1 - 0.15 11.5 1.4 0.26 10.8 1.4 1.4 1 0 0 1 1 1 0 zinc-ribbon domain UPF0547 PF10571.9 KXS11819.1 - 1.3 9.2 5.2 2.4 8.3 5.1 1.5 1 1 0 1 1 1 0 Uncharacterised protein family UPF0547 Exo_endo_phos PF03372.23 KXS11820.1 - 1.4e-12 47.6 0.4 2.1e-12 47.1 0.4 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Ank_3 PF13606.6 KXS11821.1 - 0.00087 19.6 0.0 0.25 12.0 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat SH3_1 PF00018.28 KXS11822.1 - 6.3e-09 35.3 0.0 9.3e-09 34.8 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KXS11822.1 - 8.9e-08 31.9 0.0 1.3e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KXS11822.1 - 0.00039 20.1 0.0 0.00064 19.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain PPR PF01535.20 KXS11823.1 - 4.9e-05 23.3 0.2 0.35 11.2 0.0 4.1 5 0 0 5 5 5 1 PPR repeat PPR_2 PF13041.6 KXS11823.1 - 0.012 15.8 0.1 0.15 12.3 0.0 2.7 3 0 0 3 3 3 0 PPR repeat family IPI_T4 PF11634.8 KXS11823.1 - 0.2 11.7 0.0 0.39 10.7 0.0 1.4 1 0 0 1 1 1 0 Nuclease inhibitor from bacteriophage T4 PPR_2 PF13041.6 KXS11824.1 - 0.14 12.4 0.0 1.5 9.1 0.0 2.5 3 0 0 3 3 3 0 PPR repeat family HEAT PF02985.22 KXS11824.1 - 0.16 12.3 0.0 0.48 10.8 0.0 1.8 1 0 0 1 1 1 0 HEAT repeat Ank_3 PF13606.6 KXS11825.1 - 0.0019 18.5 0.0 1.3 9.9 0.1 3.3 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 KXS11825.1 - 0.02 15.3 0.5 7.8 7.1 0.2 3.4 3 0 0 3 3 3 0 Ankyrin repeat Ank_2 PF12796.7 KXS11825.1 - 0.038 14.6 0.2 0.17 12.5 0.2 2.1 2 1 0 2 2 2 0 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXS11825.1 - 0.074 13.7 0.0 0.22 12.2 0.0 1.8 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Maf1 PF09174.10 KXS11826.1 - 8.6e-23 81.4 0.0 6.9e-22 78.4 0.0 2.0 1 1 0 1 1 1 1 Maf1 regulator DUF568 PF04526.13 KXS11827.1 - 0.077 13.7 0.1 10 6.9 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF568) MscL PF01741.18 KXS11830.1 - 9.2e-28 97.0 0.1 1.1e-27 96.7 0.1 1.1 1 0 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL Virul_fac_BrkB PF03631.15 KXS11830.1 - 0.0025 17.5 4.8 0.0026 17.4 2.6 1.8 1 1 1 2 2 2 1 Virulence factor BrkB zf-ribbon_3 PF13248.6 KXS11830.1 - 0.0034 16.8 0.9 0.0056 16.0 0.9 1.4 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.7 KXS11830.1 - 0.0082 16.2 0.6 0.013 15.5 0.6 1.2 1 0 0 1 1 1 1 Double zinc ribbon Orf78 PF06024.12 KXS11830.1 - 0.19 12.0 0.0 0.29 11.5 0.0 1.2 1 0 0 1 1 1 0 Orf78 (ac78) MscL PF01741.18 KXS11831.1 - 1.5e-27 96.3 2.7 5.5e-27 94.5 2.7 1.7 1 1 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL DZR PF12773.7 KXS11831.1 - 0.0089 16.0 1.3 0.014 15.4 1.3 1.2 1 0 0 1 1 1 1 Double zinc ribbon zf-C3HC4_3 PF13920.6 KXS11831.1 - 0.024 14.5 1.2 0.035 13.9 1.2 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_2 PF13240.6 KXS11831.1 - 0.14 11.9 1.5 0.24 11.2 1.5 1.4 1 0 0 1 1 1 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 KXS11831.1 - 0.17 11.4 2.8 0.3 10.5 2.8 1.5 1 0 0 1 1 1 0 zinc-ribbon domain UPF0547 PF10571.9 KXS11831.1 - 0.21 11.7 2.4 0.38 10.9 2.4 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 zf-HYPF PF07503.12 KXS11831.1 - 0.27 11.0 3.1 6.3 6.7 0.5 2.2 2 0 0 2 2 2 0 HypF finger DUF35_N PF12172.8 KXS11831.1 - 1.1 9.2 5.1 17 5.4 0.1 2.4 2 1 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Zn_clus PF00172.18 KXS11832.1 - 8.3e-08 32.2 14.1 1.1e-07 31.8 14.1 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 7tm_1 PF00001.21 KXS11833.1 - 3.7e-09 36.3 0.0 5.1e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) GCP_C_terminal PF04130.13 KXS11834.1 - 2.4e-15 56.8 0.0 5.3e-15 55.7 0.0 1.6 1 1 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 KXS11834.1 - 3.2e-08 33.6 0.0 6.6e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal Ribosomal_L29 PF00831.23 KXS11835.1 - 1.6e-19 69.6 1.6 1.6e-19 69.6 1.6 2.1 2 0 0 2 2 2 1 Ribosomal L29 protein TolA_bind_tri PF16331.5 KXS11835.1 - 0.035 14.2 0.4 0.035 14.2 0.4 2.2 2 1 0 2 2 2 0 TolA binding protein trimerisation DUF948 PF06103.11 KXS11835.1 - 0.053 13.8 2.1 0.08 13.2 2.1 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) NAD_binding_6 PF08030.12 KXS11835.1 - 0.093 12.8 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 Ferric reductase NAD binding domain Snapin_Pallidin PF14712.6 KXS11835.1 - 1 9.8 8.6 0.12 12.9 4.1 1.7 2 0 0 2 2 2 0 Snapin/Pallidin ER_lumen_recept PF00810.18 KXS11838.1 - 3.8e-32 112.2 13.0 4.9e-32 111.8 13.0 1.1 1 0 0 1 1 1 1 ER lumen protein retaining receptor adh_short PF00106.25 KXS11840.1 - 8.9e-26 90.6 0.1 9.3e-24 84.0 0.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXS11840.1 - 5.3e-15 55.6 0.1 1.1e-14 54.5 0.1 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXS11840.1 - 9.3e-06 25.7 0.2 1.7e-05 24.8 0.2 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXS11840.1 - 0.00014 21.4 0.2 0.00056 19.4 0.1 2.0 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 KXS11840.1 - 0.079 12.3 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Eno-Rase_NADH_b PF12242.8 KXS11840.1 - 0.092 12.5 0.0 0.22 11.3 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.6 KXS11840.1 - 0.12 12.3 0.1 0.17 11.7 0.1 1.5 1 1 0 1 1 1 0 NAD(P)H-binding adh_short PF00106.25 KXS11841.1 - 3.3e-27 95.2 0.1 7.6e-25 87.5 0.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXS11841.1 - 1.8e-14 53.8 0.0 2.4e-13 50.2 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXS11841.1 - 5.2e-08 33.0 0.2 1.1e-07 32.0 0.2 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXS11841.1 - 0.0002 20.9 0.1 0.00038 20.0 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family FCH PF00611.23 KXS11842.1 - 1.6e-12 47.5 0.1 1.6e-12 47.5 0.1 2.0 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.6 KXS11842.1 - 2.9e-12 46.2 0.2 5.6e-12 45.3 0.2 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXS11842.1 - 4e-11 42.3 0.1 7.9e-11 41.4 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KXS11842.1 - 4.9e-11 42.1 0.1 9.2e-11 41.3 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain TFIIA PF03153.13 KXS11842.1 - 2.3e-05 24.6 24.0 7.2e-05 23.0 15.2 2.1 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit Surface_antigen PF11054.8 KXS11842.1 - 0.071 12.8 0.5 0.11 12.1 0.5 1.3 1 0 0 1 1 1 0 Sporozoite TA4 surface antigen Chitin_bind_1 PF00187.19 KXS11843.1 - 5.5e-12 45.9 40.8 5.4e-07 30.0 16.8 2.4 2 0 0 2 2 2 2 Chitin recognition protein FAD_binding_7 PF03441.14 KXS11844.1 - 2e-76 256.0 0.1 2.9e-76 255.5 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 KXS11844.1 - 2.7e-42 144.5 0.3 4.5e-42 143.8 0.3 1.3 1 0 0 1 1 1 1 DNA photolyase Acyl-CoA_dh_1 PF00441.24 KXS11846.1 - 3e-25 89.2 3.2 4.7e-25 88.6 3.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KXS11846.1 - 1.6e-17 64.2 0.0 3.7e-17 63.0 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KXS11846.1 - 2.4e-16 59.7 0.0 4.3e-16 58.9 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KXS11846.1 - 2e-06 28.1 0.1 3.7e-06 27.2 0.1 1.4 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DUF3161 PF11362.8 KXS11846.1 - 0.019 14.9 0.0 0.044 13.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3161) DUF3645 PF12359.8 KXS11846.1 - 0.047 13.1 0.1 1.5 8.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3645) AMPK1_CBM PF16561.5 KXS11847.1 - 0.32 11.3 4.0 3.6 7.9 4.0 2.5 1 1 0 1 1 1 0 Glycogen recognition site of AMP-activated protein kinase Pkinase PF00069.25 KXS11848.1 - 1.4e-30 106.6 0.0 1.7e-30 106.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS11848.1 - 2.5e-30 105.6 0.0 2.8e-30 105.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXS11848.1 - 2.7e-05 23.6 0.0 3.4e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KXS11848.1 - 0.00038 19.9 0.0 0.00056 19.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXS11848.1 - 0.0087 16.0 0.2 0.021 14.7 0.2 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KXS11848.1 - 0.073 12.7 0.0 0.088 12.4 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Haspin_kinase PF12330.8 KXS11848.1 - 0.076 11.9 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain 2_5_RNA_ligase2 PF13563.6 KXS11849.1 - 1.4e-29 103.0 0.0 1.9e-29 102.5 0.0 1.2 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily LigT_PEase PF02834.16 KXS11849.1 - 0.0078 16.4 0.0 0.54 10.5 0.0 2.4 2 0 0 2 2 2 2 LigT like Phosphoesterase Glyco_hydro_28 PF00295.17 KXS11850.1 - 1.6e-22 80.0 14.0 2.9e-14 52.9 5.9 2.2 1 1 1 2 2 2 2 Glycosyl hydrolases family 28 CTXphi_pIII-N1 PF16710.5 KXS11850.1 - 0.0019 18.3 0.2 0.059 13.5 0.0 2.4 2 0 0 2 2 2 1 N-terminal N1 domain of Vibrio phage CTXphi pIII Glyco_hydro_28 PF00295.17 KXS11851.1 - 5.4e-41 140.7 20.2 1.3e-40 139.5 20.1 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 DUF4210 PF13915.6 KXS11854.1 - 1.3e-15 57.7 0.0 2.5e-15 56.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.6 KXS11854.1 - 6.5e-08 32.6 0.0 1.2e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 Chromosome segregation during meiosis Glyco_hydro_18 PF00704.28 KXS11856.1 - 5.5e-15 55.9 0.0 5.9e-15 55.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DIOX_N PF14226.6 KXS11856.1 - 0.025 15.3 0.0 0.026 15.3 0.0 1.2 1 0 0 1 1 1 0 non-haem dioxygenase in morphine synthesis N-terminal DUF1851 PF08906.11 KXS11856.1 - 0.098 12.6 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1851) Ank_3 PF13606.6 KXS11857.1 - 0.0032 17.8 0.0 0.15 12.7 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.7 KXS11857.1 - 0.0054 17.3 0.0 3.2 8.4 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Phage_T4_gp19 PF06841.12 KXS11857.1 - 0.073 12.9 0.3 0.14 12.0 0.3 1.5 1 0 0 1 1 1 0 T4-like virus tail tube protein gp19 Ank_5 PF13857.6 KXS11857.1 - 0.13 12.6 0.1 5 7.6 0.0 2.7 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Methyltransf_28 PF02636.17 KXS11858.1 - 0.016 14.8 0.0 0.019 14.6 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_25 PF13649.6 KXS11858.1 - 0.037 14.7 0.0 0.068 13.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain EF1_GNE PF00736.19 KXS11859.1 - 1.5e-32 111.6 1.2 1.5e-32 111.6 1.2 1.8 2 0 0 2 2 2 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 KXS11859.1 - 1.4e-11 44.6 6.1 1.4e-11 44.6 6.1 2.8 4 0 0 4 4 4 1 Eukaryotic elongation factor 1 beta central acidic region WD40 PF00400.32 KXS11860.1 - 3.6e-40 135.2 17.3 4.1e-10 40.1 0.1 8.2 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXS11860.1 - 1.7e-12 47.5 0.2 0.056 13.7 0.0 5.4 4 1 2 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KXS11860.1 - 4.3e-09 35.6 1.9 0.32 9.6 0.1 5.0 3 1 0 5 5 5 4 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KXS11860.1 - 5e-08 32.3 0.3 0.0054 15.7 0.0 4.5 3 2 1 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 KXS11860.1 - 0.00021 20.2 0.0 0.67 8.6 0.0 4.2 3 1 2 5 5 5 1 Nup133 N terminal like PALB2_WD40 PF16756.5 KXS11860.1 - 0.0018 17.2 0.1 0.0051 15.8 0.1 1.7 1 0 0 1 1 1 1 Partner and localizer of BRCA2 WD40 domain HPS3_N PF14761.6 KXS11860.1 - 0.004 16.7 0.0 0.015 14.8 0.0 1.9 2 0 0 2 2 2 1 Hermansky-Pudlak syndrome 3 NHL PF01436.21 KXS11860.1 - 0.12 12.4 0.2 2.7 8.2 0.1 3.1 3 0 0 3 3 3 0 NHL repeat DUF3826 PF12875.7 KXS11861.1 - 0.013 15.7 0.0 0.014 15.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3826) JTB PF05439.12 KXS11861.1 - 0.56 10.3 4.1 0.23 11.5 0.8 1.9 2 0 0 2 2 2 0 Jumping translocation breakpoint protein (JTB) Pkinase PF00069.25 KXS11862.1 - 4.1e-48 164.0 0.0 6e-48 163.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS11862.1 - 8.8e-22 77.6 0.0 5.7e-21 75.0 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 KXS11862.1 - 0.11 11.4 0.0 0.16 10.9 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Glycos_transf_1 PF00534.20 KXS11864.1 - 6.6e-22 77.9 0.0 2.2e-21 76.1 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KXS11864.1 - 3.5e-17 63.1 0.0 1.2e-16 61.3 0.0 1.9 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 KXS11864.1 - 2.9e-07 30.8 0.0 7.9e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 PPR_2 PF13041.6 KXS11864.1 - 0.0017 18.5 0.1 1.3 9.2 0.0 2.6 2 0 0 2 2 2 2 PPR repeat family Glyco_transf_7C PF02709.14 KXS11864.1 - 0.0058 16.3 0.1 0.021 14.5 0.1 1.9 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.9 KXS11864.1 - 0.007 15.9 0.0 0.014 14.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Dimer_Tnp_hAT PF05699.14 KXS11865.1 - 1.2e-16 60.2 0.1 4.2e-16 58.5 0.1 1.7 1 1 1 2 2 2 2 hAT family C-terminal dimerisation region EKLF_TAD1 PF16832.5 KXS11865.1 - 0.15 11.9 1.8 5.3 7.0 0.0 2.2 2 0 0 2 2 2 0 Erythroid krueppel-like transcription factor, transactivation 1 SMODS PF18144.1 KXS11866.1 - 0.033 14.3 0.0 0.061 13.5 0.0 1.3 1 0 0 1 1 1 0 Second Messenger Oligonucleotide or Dinucleotide Synthetase domain TMEM237 PF15383.6 KXS11867.1 - 2.9e-05 23.3 0.1 3.7e-05 22.9 0.1 1.1 1 0 0 1 1 1 1 Transmembrane protein 237 ANAPC4_WD40 PF12894.7 KXS11868.1 - 2.1e-12 47.2 0.1 0.0017 18.6 0.0 7.7 6 2 2 8 8 8 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KXS11868.1 - 2.4e-12 47.2 7.9 0.0031 18.3 0.1 8.5 10 0 0 10 10 10 3 WD domain, G-beta repeat RCC1 PF00415.18 KXS11869.1 - 1.2e-52 176.3 10.5 2.8e-12 47.1 0.2 6.1 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KXS11869.1 - 2.2e-29 100.6 12.8 1.6e-07 31.0 2.4 5.5 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat NDUF_B7 PF05676.13 KXS11870.1 - 1.5e-22 79.0 5.9 1.7e-22 78.9 5.9 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.10 KXS11870.1 - 0.0024 17.9 0.5 0.0029 17.6 0.5 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Myb_DNA-bind_2 PF08914.11 KXS11871.1 - 1e-20 73.7 0.9 3.4e-15 56.0 0.2 2.6 2 0 0 2 2 2 2 Rap1 Myb domain BRCT_2 PF16589.5 KXS11871.1 - 5.3e-06 26.7 0.0 1.6e-05 25.2 0.0 1.8 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Rap1-DNA-bind PF09197.10 KXS11871.1 - 0.046 14.3 2.7 2.4 8.8 0.8 3.1 2 1 0 2 2 2 0 Rap1, DNA-binding Rap1_C PF11626.8 KXS11872.1 - 1.5e-08 34.6 0.0 3.1e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain MutS_V PF00488.21 KXS11873.1 - 8.2e-74 247.7 0.0 1.6e-73 246.7 0.0 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KXS11873.1 - 2.9e-40 138.5 1.1 8.2e-40 137.1 1.1 1.8 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 KXS11873.1 - 1e-32 112.7 1.3 3.4e-32 111.0 0.2 2.4 3 0 0 3 3 3 1 MutS domain I MutS_II PF05188.17 KXS11873.1 - 1.1e-12 48.4 0.1 6.4e-12 45.9 0.1 2.5 1 1 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 KXS11873.1 - 5.1e-12 46.0 0.2 1.1e-11 44.9 0.2 1.6 1 0 0 1 1 1 1 MutS family domain IV BUD22 PF09073.10 KXS11873.1 - 3.6 6.8 21.5 7.4 5.8 21.5 1.4 1 0 0 1 1 1 0 BUD22 2OG-FeII_Oxy_2 PF13532.6 KXS11874.1 - 9e-23 81.5 0.0 5.4e-22 78.9 0.0 2.0 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-GRF PF06839.12 KXS11874.1 - 0.088 12.9 11.1 0.91 9.7 11.1 2.3 1 1 0 1 1 1 0 GRF zinc finger adh_short PF00106.25 KXS11875.1 - 3.4e-38 131.1 0.0 4e-38 130.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXS11875.1 - 4.7e-28 98.3 0.0 5.5e-28 98.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXS11875.1 - 2.5e-06 27.5 0.0 3.7e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXS11875.1 - 0.00013 21.5 0.0 0.00024 20.6 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.26 KXS11875.1 - 0.027 14.5 0.0 0.049 13.6 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase GDP_Man_Dehyd PF16363.5 KXS11875.1 - 0.16 11.3 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Ank_2 PF12796.7 KXS11876.1 - 0.019 15.5 0.0 0.044 14.4 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXS11876.1 - 0.024 15.1 0.1 0.22 12.2 0.0 2.7 2 0 0 2 2 2 0 Ankyrin repeat Ank PF00023.30 KXS11876.1 - 0.044 14.2 0.1 0.18 12.3 0.0 2.0 2 0 0 2 2 2 0 Ankyrin repeat Glyco_transf_4 PF13439.6 KXS11877.1 - 0.12 12.4 0.3 0.21 11.5 0.3 1.4 1 0 0 1 1 1 0 Glycosyltransferase Family 4 Aminotran_1_2 PF00155.21 KXS11878.1 - 2.6e-14 53.2 0.0 3.1e-14 52.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II RRP7 PF12923.7 KXS11879.1 - 1e-21 77.3 0.2 1e-21 77.3 0.2 3.3 3 1 0 3 3 3 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain RRM_Rrp7 PF17799.1 KXS11879.1 - 1.4e-06 28.2 0.0 6.9e-06 25.9 0.0 2.0 1 1 0 1 1 1 1 Rrp7 RRM-like N-terminal domain RRM_1 PF00076.22 KXS11879.1 - 0.00017 21.3 0.0 0.012 15.4 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Apt1 PF10351.9 KXS11879.1 - 0.98 8.2 10.9 0.071 11.9 1.4 2.2 2 0 0 2 2 2 0 Golgi-body localisation protein domain 3Beta_HSD PF01073.19 KXS11880.1 - 5.2e-46 156.9 0.0 6.5e-46 156.6 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KXS11880.1 - 1.1e-27 97.1 0.0 1.7e-27 96.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KXS11880.1 - 1.5e-15 57.6 0.0 2.2e-15 57.0 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KXS11880.1 - 3.2e-08 33.4 0.0 5.2e-07 29.4 0.0 2.4 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KXS11880.1 - 8.7e-07 28.4 0.0 4.9e-06 25.9 0.0 2.0 2 0 0 2 2 2 1 Male sterility protein NmrA PF05368.13 KXS11880.1 - 1.3e-05 24.9 0.0 2.1e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.17 KXS11880.1 - 0.00013 21.2 0.0 0.00019 20.6 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KXS11880.1 - 0.00071 18.8 0.0 0.0015 17.7 0.0 1.5 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RELT PF12606.8 KXS11880.1 - 0.0008 18.3 0.7 0.0014 17.5 0.7 1.3 1 0 0 1 1 1 1 Tumour necrosis factor receptor superfamily member 19 AP_endonuc_2 PF01261.24 KXS11880.1 - 0.00093 18.7 0.0 0.0013 18.2 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel KR PF08659.10 KXS11880.1 - 0.12 12.3 0.1 1.3 8.9 0.0 2.1 1 1 1 2 2 2 0 KR domain Sacchrp_dh_NADP PF03435.18 KXS11880.1 - 0.41 10.9 2.3 3.7 7.8 1.0 3.0 2 1 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain zf-MIZ PF02891.20 KXS11881.1 - 7.7e-07 28.8 0.2 1.5e-06 27.8 0.2 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 KXS11881.1 - 0.012 15.4 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Flavokinase PF01687.17 KXS11883.1 - 2.6e-37 127.5 0.0 3e-37 127.3 0.0 1.0 1 0 0 1 1 1 1 Riboflavin kinase CDC27 PF09507.10 KXS11884.1 - 4.5e-33 115.3 17.8 2.8e-21 76.4 0.0 2.2 1 1 1 2 2 2 2 DNA polymerase subunit Cdc27 DUF2500 PF10694.9 KXS11885.1 - 2.5 8.6 9.5 0.58 10.7 5.8 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2500) DnaJ_C PF01556.18 KXS11886.1 - 6.2e-37 126.9 0.1 8.4e-37 126.5 0.1 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KXS11886.1 - 1.3e-26 92.4 1.2 2.1e-26 91.8 1.2 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KXS11886.1 - 1.9e-15 57.0 16.9 3.1e-15 56.3 16.9 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 KXS11886.1 - 1.6e-07 31.2 6.9 0.0021 18.0 0.9 2.4 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 KXS11886.1 - 4.9e-05 23.3 5.6 0.074 13.1 1.7 2.3 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_2 PF13240.6 KXS11886.1 - 0.089 12.5 0.2 0.089 12.5 0.2 3.8 4 0 0 4 4 4 0 zinc-ribbon domain SLATT_5 PF18160.1 KXS11886.1 - 0.16 11.3 0.1 0.24 10.7 0.1 1.2 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 Ogr_Delta PF04606.12 KXS11886.1 - 0.25 11.4 0.2 0.25 11.4 0.2 2.4 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger DZR PF12773.7 KXS11886.1 - 0.3 11.1 10.0 1.1 9.3 10.1 1.9 1 1 0 1 1 1 0 Double zinc ribbon Lar_restr_allev PF14354.6 KXS11886.1 - 1.1 9.7 11.4 1.2 9.6 0.1 3.5 2 2 1 3 3 3 0 Restriction alleviation protein Lar TackOD1 PF18551.1 KXS11886.1 - 2.6 7.7 11.9 0.69 9.6 0.9 2.8 2 1 1 3 3 3 0 Thaumarchaeal output domain 1 DUF678 PF05077.12 KXS11886.1 - 3.1 8.0 7.4 1.5 9.0 3.0 2.6 1 1 0 1 1 1 0 Protein of unknown function (DUF678) zf-RanBP PF00641.18 KXS11886.1 - 3.4 7.1 7.8 12 5.4 1.1 2.5 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others zinc_ribbon_9 PF14369.6 KXS11886.1 - 8.1 6.8 12.6 27 5.1 0.2 3.7 3 1 1 4 4 3 0 zinc-ribbon zinc-ribbons_6 PF07191.12 KXS11886.1 - 9.1 6.3 10.3 71 3.5 1.5 2.3 1 1 1 2 2 2 0 zinc-ribbons FdhE PF04216.12 KXS11886.1 - 9.2 6.1 6.2 4.2 7.2 3.6 1.7 1 1 0 1 1 1 0 Protein involved in formate dehydrogenase formation SOR_SNZ PF01680.17 KXS11887.1 - 1.2e-112 374.6 6.3 1.9e-112 374.1 6.3 1.3 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.14 KXS11887.1 - 1.8e-09 37.3 4.8 1.6e-07 30.9 0.1 2.6 2 1 1 3 3 3 2 Thiazole biosynthesis protein ThiG Dus PF01207.17 KXS11887.1 - 0.00027 20.1 0.3 0.43 9.6 0.1 2.5 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) TetR_C_27 PF17935.1 KXS11887.1 - 0.00098 19.2 0.0 0.0077 16.3 0.0 2.2 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain His_biosynth PF00977.21 KXS11887.1 - 0.00099 18.6 0.2 0.12 11.8 0.0 3.0 2 1 1 3 3 3 2 Histidine biosynthesis protein NanE PF04131.14 KXS11887.1 - 0.0051 16.0 1.7 0.1 11.8 0.0 2.6 2 1 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase IGPS PF00218.21 KXS11887.1 - 0.011 14.9 0.1 0.55 9.4 0.0 2.5 2 1 0 2 2 2 0 Indole-3-glycerol phosphate synthase ERCC4 PF02732.15 KXS11888.1 - 1.3e-17 64.4 0.3 3e-17 63.3 0.0 1.7 1 1 1 2 2 2 1 ERCC4 domain Pox_Ag35 PF03286.14 KXS11888.1 - 0.004 17.0 10.9 0.0086 15.9 10.9 1.5 1 0 0 1 1 1 1 Pox virus Ag35 surface protein CPSF100_C PF13299.6 KXS11888.1 - 0.031 14.4 5.2 0.057 13.6 5.2 1.5 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF3303 PF11746.8 KXS11888.1 - 0.11 12.8 0.1 0.38 11.0 0.0 1.9 2 0 0 2 2 1 0 Protein of unknown function (DUF3303) CUE PF02845.16 KXS11888.1 - 0.11 12.2 0.1 0.31 10.8 0.1 1.8 1 0 0 1 1 1 0 CUE domain Nop53 PF07767.11 KXS11888.1 - 0.15 11.4 28.1 0.25 10.7 28.1 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DUF4484 PF14831.6 KXS11888.1 - 0.65 10.0 6.5 6.7 6.7 6.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4484) CDC27 PF09507.10 KXS11888.1 - 0.95 8.8 24.4 1.5 8.2 24.4 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Macoilin PF09726.9 KXS11888.1 - 1.4 7.4 13.5 2.1 6.8 10.5 2.2 2 0 0 2 2 2 0 Macoilin family Presenilin PF01080.17 KXS11888.1 - 2.1 7.0 9.2 2.9 6.6 9.2 1.2 1 0 0 1 1 1 0 Presenilin AAA_11 PF13086.6 KXS11888.1 - 5.2 6.8 11.3 11 5.7 11.3 1.5 1 0 0 1 1 1 0 AAA domain Connexin PF00029.19 KXS11888.1 - 5.6 6.6 8.9 10 5.8 8.9 1.4 1 0 0 1 1 1 0 Connexin Hid1 PF12722.7 KXS11888.1 - 8.3 4.4 7.5 11 4.0 7.5 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RR_TM4-6 PF06459.12 KXS11888.1 - 9.8 5.9 18.5 18 5.0 18.5 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Glyoxalase_4 PF13669.6 KXS11889.1 - 2.5e-21 76.0 0.0 4.3e-21 75.2 0.0 1.4 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 KXS11889.1 - 0.0052 16.9 0.1 0.0085 16.2 0.1 1.4 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.25 KXS11889.1 - 0.011 15.9 0.0 0.016 15.4 0.0 1.4 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily RNase_T PF00929.24 KXS11890.1 - 1.3e-14 55.0 0.0 2e-14 54.5 0.0 1.3 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 KXS11890.1 - 5.4e-05 23.0 0.0 0.00017 21.4 0.0 1.7 1 1 0 1 1 1 1 3'-5' exonuclease ASH PF15780.5 KXS11891.1 - 1.6e-32 111.6 12.2 8.2e-05 22.7 0.1 11.7 12 0 0 12 12 12 5 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 KXS11891.1 - 1.3e-15 57.1 4.6 0.0026 17.6 0.0 9.1 10 0 0 10 10 10 4 MSP (Major sperm protein) domain PapD-like PF14874.6 KXS11891.1 - 1.7e-09 37.8 0.2 0.55 10.4 0.0 5.8 6 0 0 6 6 6 3 Flagellar-associated PapD-like MYCBPAP PF14646.6 KXS11891.1 - 3.7e-09 36.1 0.9 0.62 8.9 0.0 7.4 7 1 0 8 8 8 3 MYCBP-associated protein family fn3_5 PF06280.12 KXS11891.1 - 0.00011 22.8 0.0 1.2 9.9 0.0 5.1 5 0 0 5 5 5 1 Fn3-like domain TetR_N PF00440.23 KXS11891.1 - 0.12 12.2 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family PDEase_I PF00233.19 KXS11892.1 - 2.4e-82 276.2 0.2 3.1e-82 275.9 0.2 1.1 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Ndr PF03096.14 KXS11892.1 - 0.086 11.5 0.0 0.15 10.8 0.0 1.3 1 0 0 1 1 1 0 Ndr family ArfGap PF01412.18 KXS11893.1 - 2.8e-31 108.0 0.0 3e-31 107.9 0.0 1.0 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf UCH PF00443.29 KXS11894.1 - 2.3e-59 201.0 0.1 3.1e-59 200.6 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KXS11894.1 - 1.6e-30 106.8 0.8 1.3e-23 84.1 0.1 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 KXS11894.1 - 0.026 14.0 4.8 0.26 10.7 1.7 2.9 3 1 0 3 3 3 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Calreticulin PF00262.18 KXS11895.1 - 2.3e-165 549.9 14.1 3.2e-165 549.4 14.1 1.2 1 0 0 1 1 1 1 Calreticulin family HTH_11 PF08279.12 KXS11896.1 - 4.6e-05 23.3 0.1 0.068 13.1 0.0 2.4 2 0 0 2 2 2 2 HTH domain HTH_28 PF13518.6 KXS11896.1 - 8.1e-05 22.7 0.4 0.24 11.5 0.1 3.9 5 0 0 5 5 5 1 Helix-turn-helix domain HTH_33 PF13592.6 KXS11896.1 - 0.00053 19.6 0.0 0.0028 17.3 0.0 2.2 2 0 0 2 2 2 1 Winged helix-turn helix HTH_Tnp_IS630 PF01710.16 KXS11896.1 - 0.0087 16.1 0.0 6.1 6.9 0.0 2.6 2 0 0 2 2 2 2 Transposase IFT57 PF10498.9 KXS11896.1 - 0.013 14.5 0.0 0.018 14.0 0.0 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 HTH_23 PF13384.6 KXS11896.1 - 0.039 13.8 0.6 2 8.3 0.1 2.9 3 0 0 3 3 3 0 Homeodomain-like domain HTH_DeoR PF08220.12 KXS11896.1 - 0.053 13.3 0.5 1.2 9.0 0.0 2.4 2 0 0 2 2 2 0 DeoR-like helix-turn-helix domain HTH_3 PF01381.22 KXS11896.1 - 0.055 13.5 0.0 6.4 6.9 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix HTH_32 PF13565.6 KXS11896.1 - 0.18 12.5 0.2 15 6.3 0.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_17 PF12728.7 KXS11896.1 - 0.18 12.0 0.0 11 6.4 0.0 3.2 4 0 0 4 4 4 0 Helix-turn-helix domain YbjQ_1 PF01906.17 KXS11897.1 - 0.062 13.9 0.2 0.58 10.8 0.2 2.2 1 1 0 1 1 1 0 Putative heavy-metal-binding C2 PF00168.30 KXS11898.1 - 2.1e-22 79.4 0.0 4e-22 78.5 0.0 1.5 1 0 0 1 1 1 1 C2 domain YbjQ_1 PF01906.17 KXS11898.1 - 0.0017 19.0 0.0 0.57 10.8 0.0 2.5 2 0 0 2 2 2 2 Putative heavy-metal-binding TFIIS_M PF07500.14 KXS11900.1 - 5.7e-28 97.6 0.1 8.3e-28 97.1 0.1 1.3 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 KXS11900.1 - 9.2e-16 57.4 4.6 1.5e-15 56.7 4.6 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) XRN_M PF17846.1 KXS11900.1 - 0.027 13.5 0.2 0.035 13.1 0.2 1.2 1 0 0 1 1 1 0 Xrn1 helical domain zf-DNL PF05180.12 KXS11900.1 - 0.31 11.0 3.1 0.6 10.1 3.1 1.5 1 0 0 1 1 1 0 DNL zinc finger Pro_isomerase PF00160.21 KXS11901.1 - 3.5e-49 167.1 0.1 6.2e-49 166.3 0.1 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Rtf2 PF04641.12 KXS11901.1 - 3.4e-07 29.9 0.0 6.4e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 Rtf2 RING-finger U-box PF04564.15 KXS11901.1 - 0.0039 17.3 0.0 0.013 15.6 0.0 1.8 2 0 0 2 2 2 1 U-box domain SBP_bac_6 PF13343.6 KXS11901.1 - 0.052 12.9 0.0 0.08 12.3 0.0 1.2 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein Mito_carr PF00153.27 KXS11902.1 - 4.6e-60 199.6 6.3 3e-21 75.2 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein HMD PF03201.16 KXS11902.1 - 0.0012 19.0 0.0 2.6 8.4 0.0 3.2 3 0 0 3 3 3 2 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase Ribonuc_2-5A PF06479.12 KXS11903.1 - 2.7e-48 163.3 0.3 4.2e-48 162.7 0.3 1.3 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase PF00069.25 KXS11903.1 - 2.3e-40 138.6 0.0 5.4e-30 104.6 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXS11903.1 - 7.5e-21 74.6 0.0 1.3e-19 70.5 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXS11903.1 - 1.3e-06 27.5 0.0 2.2e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KXS11903.1 - 0.0047 16.3 0.0 0.0085 15.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 KXS11903.1 - 0.015 14.8 0.0 0.033 13.7 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.23 KXS11903.1 - 0.04 13.8 0.2 0.41 10.5 0.0 2.4 2 1 1 3 3 3 0 Phosphotransferase enzyme family Calcipressin PF04847.12 KXS11906.1 - 3.5e-23 82.3 0.0 6.2e-23 81.5 0.0 1.6 1 1 0 1 1 1 1 Calcipressin ERO1 PF04137.15 KXS11907.1 - 6.2e-122 407.2 0.0 7.2e-122 407.0 0.0 1.0 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) Pkinase PF00069.25 KXS11908.1 - 1.9e-75 253.6 0.0 2.3e-75 253.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS11908.1 - 6.5e-38 130.5 0.0 8.6e-38 130.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXS11908.1 - 6.7e-06 25.6 0.0 8.8e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 KXS11908.1 - 0.0086 15.7 0.0 0.58 9.7 0.0 2.1 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 KXS11908.1 - 0.1 11.5 0.2 0.15 11.0 0.2 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Sushi_2 PF09014.10 KXS11908.1 - 0.11 12.4 0.2 0.23 11.4 0.2 1.5 1 0 0 1 1 1 0 Beta-2-glycoprotein-1 fifth domain Kdo PF06293.14 KXS11908.1 - 0.15 11.4 0.0 0.29 10.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TPR_1 PF00515.28 KXS11909.1 - 1.8e-15 56.0 9.7 0.00033 20.4 0.0 5.9 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.6 KXS11909.1 - 7.1e-14 51.2 14.9 0.003 17.2 0.1 5.4 3 1 2 5 5 5 4 TPR repeat TPR_2 PF07719.17 KXS11909.1 - 1.8e-13 49.5 12.5 0.014 15.5 0.0 6.2 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_17 PF13431.6 KXS11909.1 - 3.9e-13 48.8 9.1 0.017 15.4 0.5 6.2 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_20 PF14561.6 KXS11909.1 - 6.3e-13 48.9 6.1 0.0043 17.3 0.1 5.9 2 2 3 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.6 KXS11909.1 - 1.7e-12 47.0 14.7 0.009 16.8 0.0 7.2 3 2 4 7 7 6 5 Tetratricopeptide repeat TPR_8 PF13181.6 KXS11909.1 - 1.5e-11 43.5 6.3 0.058 13.6 0.0 6.7 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 KXS11909.1 - 1.8e-11 44.4 18.0 0.00062 20.2 0.8 5.4 4 2 3 7 7 6 4 Tetratricopeptide repeat TPR_16 PF13432.6 KXS11909.1 - 8.9e-11 42.3 13.7 7e-05 23.4 0.7 4.9 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 KXS11909.1 - 4.6e-07 30.0 10.4 0.061 13.6 0.6 4.8 4 1 2 6 6 6 4 Tetratricopeptide repeat TPR_9 PF13371.6 KXS11909.1 - 4.1e-06 26.8 5.3 0.28 11.4 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.6 KXS11909.1 - 9.2e-06 25.3 4.8 0.0016 18.4 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KXS11909.1 - 0.0012 19.0 3.9 0.033 14.4 1.6 2.7 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 NADPH_Ox PF08414.10 KXS11909.1 - 0.0032 17.8 0.1 0.081 13.3 0.0 3.0 2 0 0 2 2 2 1 Respiratory burst NADPH oxidase TPR_6 PF13174.6 KXS11909.1 - 0.015 15.9 6.4 8.4 7.3 0.0 5.5 6 0 0 6 6 5 0 Tetratricopeptide repeat DUF1641 PF07849.11 KXS11909.1 - 0.67 9.9 3.8 8.5 6.4 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1641) TPR_10 PF13374.6 KXS11909.1 - 4 7.4 12.9 6.7 6.7 0.0 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Pkinase PF00069.25 KXS11910.1 - 1.9e-42 145.5 0.0 2.6e-42 145.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS11910.1 - 1.4e-25 90.0 0.0 2.3e-25 89.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXS11910.1 - 2.8e-06 26.9 0.0 5.1e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KXS11910.1 - 0.0017 18.3 0.0 0.66 9.8 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXS11910.1 - 0.0074 15.1 0.0 0.012 14.5 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 KXS11910.1 - 0.025 13.5 0.0 0.038 13.0 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain DUF1501 PF07394.12 KXS11911.1 - 0.0072 15.4 1.5 0.0072 15.4 1.5 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1501) CPSase_L_D2 PF02786.17 KXS11912.1 - 6.2e-77 257.9 0.0 1.1e-76 257.0 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 KXS11912.1 - 1.5e-44 151.0 0.3 1.5e-44 151.0 0.3 2.3 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KXS11912.1 - 1.3e-32 112.1 0.0 1.1e-31 109.1 0.0 2.4 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain PCC_BT PF18140.1 KXS11912.1 - 1.1e-21 77.5 0.2 2.6e-21 76.3 0.2 1.7 1 0 0 1 1 1 1 Propionyl-coenzyme A carboxylase BT domain Biotin_lipoyl PF00364.22 KXS11912.1 - 3.6e-17 62.0 1.1 3.6e-17 62.0 1.1 2.3 3 0 0 3 3 3 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 KXS11912.1 - 5.4e-10 39.1 0.0 1.3e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KXS11912.1 - 4.2e-09 36.2 0.0 1.2e-08 34.8 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 KXS11912.1 - 5.8e-07 29.2 0.1 0.0043 16.9 0.0 2.5 1 1 1 2 2 2 2 Biotin-lipoyl like HlyD_3 PF13437.6 KXS11912.1 - 3.2e-05 24.6 0.9 0.31 11.8 0.1 2.8 2 0 0 2 2 2 2 HlyD family secretion protein ATP-grasp_3 PF02655.14 KXS11912.1 - 9.9e-05 22.4 0.0 0.00021 21.4 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain HlyD_D23 PF16576.5 KXS11912.1 - 0.0056 15.9 0.7 0.2 10.8 0.0 2.6 2 1 1 3 3 3 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion GARS_A PF01071.19 KXS11912.1 - 0.0089 15.8 0.0 0.019 14.8 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain PASTA PF03793.19 KXS11912.1 - 0.0092 15.8 0.9 0.29 11.0 0.2 3.1 2 0 0 2 2 2 1 PASTA domain GCV_H PF01597.19 KXS11912.1 - 0.028 14.3 0.3 0.084 12.8 0.3 1.7 1 0 0 1 1 1 0 Glycine cleavage H-protein NQRA PF05896.11 KXS11912.1 - 0.03 13.8 0.1 0.051 13.0 0.1 1.3 1 0 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) RnfC_N PF13375.6 KXS11912.1 - 0.053 13.5 0.2 0.18 11.8 0.1 1.9 2 0 0 2 2 1 0 RnfC Barrel sandwich hybrid domain DUF2118 PF09891.9 KXS11912.1 - 0.055 13.4 0.1 0.15 12.1 0.1 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) Carboxyl_trans PF01039.22 KXS11913.1 - 5.9e-192 638.7 0.1 6.8e-192 638.5 0.1 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 KXS11913.1 - 0.011 15.3 5.5 0.017 14.6 0.0 3.2 3 1 0 4 4 4 0 Malonate decarboxylase gamma subunit (MdcE) NmrA PF05368.13 KXS11914.1 - 2.2e-16 60.1 0.6 5.8e-16 58.8 0.6 1.6 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXS11914.1 - 0.00031 20.7 0.0 0.00048 20.1 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding AidB_N PF18158.1 KXS11916.1 - 7.8e-28 97.4 0.0 1.4e-27 96.6 0.0 1.4 1 0 0 1 1 1 1 Adaptive response protein AidB N-terminal domain Acyl-CoA_dh_1 PF00441.24 KXS11916.1 - 6.9e-26 91.3 3.4 5.4e-25 88.4 3.4 2.1 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.11 KXS11916.1 - 6.2e-09 36.2 1.6 0.00074 19.8 0.0 2.5 2 1 0 2 2 2 2 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KXS11916.1 - 3.8e-07 30.2 0.0 2e-06 27.9 0.0 2.1 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Aminotran_4 PF01063.19 KXS11918.1 - 7.9e-34 117.5 0.0 9.6e-34 117.2 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV COesterase PF00135.28 KXS11919.1 - 1e-90 305.1 0.0 1.2e-90 304.9 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXS11919.1 - 6.2e-07 29.5 0.2 7.9e-06 25.9 0.2 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold p450 PF00067.22 KXS11920.1 - 9.5e-61 205.9 0.0 1.3e-60 205.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF2236 PF09995.9 KXS11921.1 - 6.7e-24 85.4 0.7 9.8e-24 84.8 0.7 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) Glyco_hydro_47 PF01532.20 KXS11923.1 - 8.8e-122 407.3 0.0 1e-121 407.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 ChaC PF04752.12 KXS11924.1 - 0.0033 17.5 0.0 0.012 15.7 0.0 2.0 1 1 0 1 1 1 1 ChaC-like protein Glyco_hydro_38N PF01074.22 KXS11926.1 - 8.3e-85 284.6 1.9 1.4e-84 283.9 1.9 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 KXS11926.1 - 6.7e-55 186.5 0.0 1e-54 185.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 KXS11926.1 - 6.3e-26 90.4 0.1 1.8e-25 88.9 0.1 1.8 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 KXS11926.1 - 4.3e-09 36.4 0.0 1e-08 35.2 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain PI-PLC-X PF00388.19 KXS11927.1 - 5.4e-45 152.5 0.0 8.8e-45 151.9 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 KXS11927.1 - 4.5e-23 81.8 0.0 9.2e-22 77.6 0.0 2.4 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_1 PF00036.32 KXS11927.1 - 1.3e-05 24.4 0.0 3.6e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 KXS11927.1 - 6.8e-05 22.6 0.1 0.00024 20.9 0.0 1.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_7 PF13499.6 KXS11927.1 - 0.0012 19.2 0.1 0.0043 17.5 0.0 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_4 PF12763.7 KXS11927.1 - 0.0024 17.8 0.0 0.0055 16.6 0.0 1.5 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.6 KXS11927.1 - 0.0041 16.9 0.0 0.013 15.3 0.0 1.9 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.6 KXS11927.1 - 0.082 12.4 0.0 0.2 11.2 0.0 1.7 1 0 0 1 1 1 0 EF hand Methyltransf_11 PF08241.12 KXS11928.1 - 7e-09 36.2 0.0 2.1e-08 34.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXS11928.1 - 2.1e-07 31.6 0.0 5.9e-07 30.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXS11928.1 - 0.00082 20.1 0.0 0.0018 19.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain DUF1349 PF07081.11 KXS11929.1 - 3e-35 121.5 0.0 3.8e-35 121.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) Ribosomal_L7Ae PF01248.26 KXS11931.1 - 4.7e-21 74.3 0.0 6.7e-21 73.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DnaJ PF00226.31 KXS11932.1 - 6.8e-20 71.0 0.6 1.4e-19 69.9 0.6 1.6 1 0 0 1 1 1 1 DnaJ domain zf-C2H2_jaz PF12171.8 KXS11932.1 - 5.7e-08 32.8 1.4 1.5e-06 28.3 0.2 2.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KXS11932.1 - 1.7e-07 31.5 0.2 0.012 16.0 0.1 2.5 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 KXS11932.1 - 0.00013 22.2 1.9 0.29 11.6 0.3 2.6 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KXS11932.1 - 0.00044 20.8 4.3 0.13 13.2 0.1 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KXS11932.1 - 0.0054 17.1 1.4 0.67 10.5 0.2 2.9 2 0 0 2 2 2 1 Zinc finger, C2H2 type DUF3708 PF12501.8 KXS11932.1 - 0.84 9.4 2.5 1.7 8.4 2.5 1.4 1 0 0 1 1 1 0 Phosphate ATP-binding cassette transporter zf-C2H2_6 PF13912.6 KXS11932.1 - 0.94 9.6 2.8 1.6 8.8 0.1 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger TauD PF02668.16 KXS11933.1 - 3.7e-40 138.4 0.1 4.6e-40 138.1 0.1 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family SNF5 PF04855.12 KXS11934.1 - 2.8e-44 151.7 0.1 3.6e-22 79.3 0.0 2.2 2 0 0 2 2 2 2 SNF5 / SMARCB1 / INI1 Nop14 PF04147.12 KXS11934.1 - 0.18 10.0 10.6 0.32 9.2 10.6 1.3 1 0 0 1 1 1 0 Nop14-like family SAPS PF04499.15 KXS11934.1 - 0.73 8.6 2.5 0.87 8.3 2.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CNDH2_C PF16858.5 KXS11934.1 - 1.2 8.9 11.8 0.13 12.1 7.1 1.6 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Pox_Ag35 PF03286.14 KXS11934.1 - 1.5 8.6 15.1 0.68 9.7 12.1 1.9 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Aminotran_1_2 PF00155.21 KXS11935.1 - 2.6e-25 89.4 0.0 3e-25 89.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 KXS11935.1 - 5.1e-09 35.4 0.0 7.5e-09 34.9 0.0 1.2 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase NIR_SIR PF01077.22 KXS11938.1 - 2.6e-53 179.8 0.0 1.7e-48 164.2 0.0 2.6 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 KXS11938.1 - 1.2e-26 92.4 0.0 6.3e-15 54.8 0.0 2.5 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.25 KXS11938.1 - 3.9e-25 88.7 1.6 1.3e-24 87.0 0.5 2.2 2 0 0 2 2 2 1 Flavodoxin DUF4388 PF14332.6 KXS11938.1 - 0.11 12.7 0.1 0.39 11.0 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4388) DUF2235 PF09994.9 KXS11939.1 - 2.6e-35 122.2 0.0 4e-35 121.6 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) 2-Hacid_dh_C PF02826.19 KXS11940.1 - 4.4e-55 185.8 0.1 6.8e-55 185.2 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KXS11940.1 - 1.6e-33 115.2 0.1 2.1e-33 114.8 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KXS11940.1 - 1.4e-08 35.1 0.2 3.3e-08 33.9 0.2 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase XdhC_C PF13478.6 KXS11940.1 - 0.021 15.3 0.0 0.1 13.1 0.0 2.2 2 1 0 2 2 2 0 XdhC Rossmann domain IlvN PF07991.12 KXS11940.1 - 0.03 13.9 0.1 0.099 12.2 0.1 1.9 1 1 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain 3HCDH_N PF02737.18 KXS11940.1 - 0.043 13.7 1.3 1.5 8.7 0.3 2.3 1 1 1 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ACT PF01842.25 KXS11940.1 - 0.08 12.7 0.0 0.29 10.9 0.0 1.9 2 0 0 2 2 2 0 ACT domain PrpR_N PF06506.11 KXS11940.1 - 0.12 11.9 0.0 3 7.4 0.0 2.4 2 0 0 2 2 2 0 Propionate catabolism activator Kinesin PF00225.23 KXS11941.1 - 2.6e-91 306.0 0.0 6.8e-91 304.7 0.0 1.7 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KXS11941.1 - 4.1e-22 78.7 0.0 1.7e-21 76.7 0.0 2.1 1 0 0 1 1 1 1 Microtubule binding HMMR_C PF15908.5 KXS11941.1 - 1.6e-05 25.2 1.5 1.6e-05 25.2 1.5 5.6 5 1 1 6 6 6 1 Hyaluronan mediated motility receptor C-terminal ATP-grasp_3 PF02655.14 KXS11941.1 - 0.0056 16.7 0.0 0.015 15.3 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain HIP1_clath_bdg PF16515.5 KXS11941.1 - 0.26 11.9 0.0 0.26 11.9 0.0 7.9 5 1 3 8 8 8 0 Clathrin-binding domain of Huntingtin-interacting protein 1 UPF0184 PF03670.13 KXS11941.1 - 0.39 11.1 5.7 1.4 9.3 0.0 3.8 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0184) AAA_22 PF13401.6 KXS11941.1 - 0.82 9.9 0.0 0.82 9.9 0.0 4.3 4 2 0 4 4 4 0 AAA domain NPV_P10 PF05531.12 KXS11941.1 - 1.2 9.6 14.7 15 6.1 1.4 6.6 7 0 0 7 7 7 0 Nucleopolyhedrovirus P10 protein DUF3103 PF11301.8 KXS11941.1 - 6.4 5.5 7.4 0.74 8.5 2.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3103) Zn_clus PF00172.18 KXS11943.1 - 1.6e-06 28.1 6.8 2.3e-06 27.6 6.8 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.32 KXS11944.1 - 1.9e-18 66.4 18.8 5.9e-05 23.8 0.5 6.4 6 0 0 6 6 6 4 WD domain, G-beta repeat NLE PF08154.12 KXS11944.1 - 3.5e-16 59.5 0.1 6.4e-16 58.6 0.1 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain ANAPC4_WD40 PF12894.7 KXS11944.1 - 8.9e-06 25.9 0.1 5 7.5 0.0 3.8 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KXS11944.1 - 0.0026 16.5 0.3 4.5 5.8 0.0 2.9 1 1 2 3 3 3 3 Nucleoporin Nup120/160 TPR_12 PF13424.6 KXS11945.1 - 7.7e-22 77.4 18.0 5.4e-09 36.2 1.4 4.1 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 KXS11945.1 - 1.6e-20 71.5 15.6 0.00096 19.1 0.1 6.2 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_8 PF13181.6 KXS11945.1 - 3.4e-19 67.4 11.8 0.0002 21.3 0.1 6.2 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_1 PF00515.28 KXS11945.1 - 1.3e-17 62.7 18.6 0.0024 17.6 0.1 6.2 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_7 PF13176.6 KXS11945.1 - 1.2e-14 53.1 12.1 0.035 14.1 0.2 6.2 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.6 KXS11945.1 - 4.4e-11 42.6 6.3 0.08 13.8 0.2 5.8 2 2 3 6 6 6 3 Tetratricopeptide repeat TPR_10 PF13374.6 KXS11945.1 - 4.8e-11 42.2 6.1 0.28 11.1 0.0 5.9 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_6 PF13174.6 KXS11945.1 - 1.4e-08 34.8 7.1 0.031 14.9 0.0 5.7 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KXS11945.1 - 2e-08 34.0 8.8 0.00051 19.5 2.7 2.2 1 1 1 2 2 2 2 MalT-like TPR region TPR_4 PF07721.14 KXS11945.1 - 1.8e-06 28.0 3.1 0.0071 16.9 0.6 4.1 5 1 0 5 5 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 KXS11945.1 - 4.2e-06 27.3 5.1 0.0012 19.4 0.0 3.9 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 KXS11945.1 - 2.6e-05 24.6 10.0 0.043 14.3 1.4 4.5 2 2 1 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KXS11945.1 - 0.00028 21.0 14.5 0.00035 20.7 1.9 4.1 2 2 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 KXS11945.1 - 0.00042 20.4 4.8 0.61 10.3 0.1 4.1 2 2 3 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 KXS11945.1 - 0.00083 19.0 0.6 21 4.9 0.0 5.3 5 0 0 5 5 5 0 TPR repeat RPN7 PF10602.9 KXS11945.1 - 0.00092 19.0 8.3 0.71 9.6 0.7 4.2 1 1 3 5 5 5 2 26S proteasome subunit RPN7 SPO22 PF08631.10 KXS11945.1 - 0.001 18.6 3.4 0.0015 18.1 3.4 1.3 1 0 0 1 1 1 1 Meiosis protein SPO22/ZIP4 like TPR_17 PF13431.6 KXS11945.1 - 0.0011 19.2 3.4 1.3 9.5 0.1 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_15 PF13429.6 KXS11945.1 - 0.0016 17.7 2.8 0.0048 16.1 0.2 2.4 2 1 0 2 2 2 1 Tetratricopeptide repeat DUF3856 PF12968.7 KXS11945.1 - 0.0033 17.5 6.3 0.74 9.9 0.7 3.1 1 1 2 3 3 3 2 Domain of Unknown Function (DUF3856) TPR_20 PF14561.6 KXS11945.1 - 0.012 15.9 2.3 4.7 7.6 0.5 3.6 1 1 3 4 4 4 0 Tetratricopeptide repeat BTAD PF03704.17 KXS11945.1 - 0.027 14.9 9.3 1.5 9.3 1.4 3.9 2 2 2 4 4 3 0 Bacterial transcriptional activator domain MIT PF04212.18 KXS11945.1 - 0.028 14.5 8.5 0.031 14.3 0.1 4.0 4 1 1 5 5 5 0 MIT (microtubule interacting and transport) domain Rapsyn_N PF10579.9 KXS11945.1 - 0.096 12.8 0.3 0.41 10.8 0.0 2.2 3 0 0 3 3 2 0 Rapsyn N-terminal myristoylation and linker region PPR PF01535.20 KXS11945.1 - 0.18 12.1 7.4 30 5.2 0.1 5.0 5 1 1 6 6 6 0 PPR repeat ANAPC5 PF12862.7 KXS11945.1 - 0.6 10.2 6.3 9.1 6.4 0.1 3.9 2 2 2 4 4 4 0 Anaphase-promoting complex subunit 5 SNAPc_SNAP43 PF09808.9 KXS11946.1 - 6.4e-15 55.6 0.2 7.6e-15 55.3 0.2 1.0 1 0 0 1 1 1 1 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 RRM_1 PF00076.22 KXS11947.1 - 4.4e-45 151.4 0.2 1.8e-18 66.1 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 KXS11947.1 - 8.1e-14 52.5 0.7 5.6e-11 43.4 0.7 2.8 1 1 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein Nup35_RRM_2 PF14605.6 KXS11947.1 - 2e-08 34.1 0.0 0.26 11.3 0.0 3.3 3 0 0 3 3 3 3 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 KXS11947.1 - 0.00086 18.9 0.0 1.6 8.4 0.0 2.9 2 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1866 PF08952.11 KXS11947.1 - 0.0018 18.2 0.0 0.54 10.1 0.0 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF1866) RRM_occluded PF16842.5 KXS11947.1 - 0.0049 16.7 0.0 0.28 11.1 0.0 3.1 3 1 1 4 4 4 1 Occluded RNA-recognition motif Aminotran_5 PF00266.19 KXS11948.1 - 4e-10 39.2 0.0 5.8e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KXS11948.1 - 0.00012 21.5 0.1 0.00027 20.4 0.0 1.6 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Metallophos PF00149.28 KXS11949.1 - 6.6e-38 131.3 0.1 9.4e-38 130.8 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KXS11949.1 - 1.5e-18 67.0 0.2 2.5e-18 66.3 0.2 1.4 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain EF_assoc_2 PF08356.12 KXS11950.1 - 2.9e-35 120.1 0.0 9e-35 118.5 0.0 1.8 2 0 0 2 2 1 1 EF hand associated EF_assoc_1 PF08355.12 KXS11950.1 - 8e-31 105.5 0.7 1.8e-30 104.4 0.2 1.8 2 0 0 2 2 2 1 EF hand associated Ras PF00071.22 KXS11950.1 - 1.3e-26 93.2 0.0 2.1e-20 73.0 0.0 2.4 2 1 0 2 2 2 2 Ras family Roc PF08477.13 KXS11950.1 - 5.9e-17 62.0 0.0 3.2e-11 43.5 0.0 2.9 2 1 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase EF-hand_6 PF13405.6 KXS11950.1 - 2.4e-10 39.5 0.3 0.00054 19.7 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 KXS11950.1 - 2.9e-09 37.2 1.3 0.00022 21.6 0.1 2.8 2 0 0 2 2 2 2 EF-hand domain pair MMR_HSR1 PF01926.23 KXS11950.1 - 6.9e-08 32.6 0.1 0.004 17.2 0.0 3.2 2 1 0 2 2 2 2 50S ribosome-binding GTPase EF-hand_1 PF00036.32 KXS11950.1 - 7.7e-08 31.4 3.9 0.00023 20.5 0.2 2.5 2 0 0 2 2 2 2 EF hand RsgA_GTPase PF03193.16 KXS11950.1 - 3e-06 27.2 0.1 0.093 12.6 0.0 3.5 4 0 0 4 4 3 1 RsgA GTPase AAA_22 PF13401.6 KXS11950.1 - 1.1e-05 25.8 0.0 0.12 12.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain Arf PF00025.21 KXS11950.1 - 1.7e-05 24.4 0.0 0.00041 19.8 0.0 2.7 3 0 0 3 3 3 1 ADP-ribosylation factor family Dynamin_N PF00350.23 KXS11950.1 - 2.1e-05 24.7 0.2 0.24 11.4 0.1 2.5 2 0 0 2 2 2 2 Dynamin family AAA_18 PF13238.6 KXS11950.1 - 2.4e-05 24.9 0.0 0.071 13.7 0.0 2.6 3 0 0 3 3 2 2 AAA domain AAA_16 PF13191.6 KXS11950.1 - 6.7e-05 23.3 0.0 0.23 11.9 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain ABC_tran PF00005.27 KXS11950.1 - 0.00011 22.8 0.0 0.38 11.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter EF-hand_10 PF14788.6 KXS11950.1 - 0.00015 21.6 4.7 0.0014 18.5 0.4 2.4 2 0 0 2 2 2 1 EF hand Septin PF00735.18 KXS11950.1 - 0.00027 20.3 0.1 0.05 12.9 0.0 2.7 2 1 1 3 3 3 1 Septin AAA_7 PF12775.7 KXS11950.1 - 0.00037 20.1 0.0 0.29 10.6 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region NACHT PF05729.12 KXS11950.1 - 0.00057 19.8 0.0 0.38 10.6 0.0 2.5 2 0 0 2 2 2 1 NACHT domain SRPRB PF09439.10 KXS11950.1 - 0.00068 19.1 0.0 0.49 9.8 0.0 2.3 2 0 0 2 2 2 2 Signal recognition particle receptor beta subunit AAA_29 PF13555.6 KXS11950.1 - 0.0009 18.9 0.1 0.58 9.9 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF815 PF05673.13 KXS11950.1 - 0.0014 17.8 0.0 0.2 10.8 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA PF00004.29 KXS11950.1 - 0.0016 18.9 0.0 1.8 9.0 0.0 2.7 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) EF-hand_5 PF13202.6 KXS11950.1 - 0.0019 17.6 6.2 0.034 13.7 0.7 2.8 2 0 0 2 2 2 1 EF hand RNA_helicase PF00910.22 KXS11950.1 - 0.0025 18.2 0.0 2.6 8.5 0.0 2.5 2 0 0 2 2 2 1 RNA helicase EF-hand_8 PF13833.6 KXS11950.1 - 0.0045 16.8 2.0 0.66 9.9 0.2 2.9 2 0 0 2 2 2 1 EF-hand domain pair AAA_24 PF13479.6 KXS11950.1 - 0.006 16.3 0.0 0.74 9.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KXS11950.1 - 0.0094 16.2 0.0 2.5 8.3 0.0 2.6 3 0 0 3 3 2 1 AAA domain ATPase_2 PF01637.18 KXS11950.1 - 0.01 15.8 0.0 0.28 11.0 0.0 2.4 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_5 PF07728.14 KXS11950.1 - 0.012 15.7 0.0 1 9.3 0.0 2.6 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 KXS11950.1 - 0.012 15.2 0.0 4.2 6.9 0.0 2.7 3 0 0 3 3 2 0 AAA domain Viral_helicase1 PF01443.18 KXS11950.1 - 0.013 15.2 0.0 0.88 9.3 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase DUF87 PF01935.17 KXS11950.1 - 0.014 15.5 0.1 0.34 11.0 0.0 2.2 2 0 0 2 2 2 0 Helicase HerA, central domain FtsK_SpoIIIE PF01580.18 KXS11950.1 - 0.016 14.5 0.1 0.52 9.6 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family cobW PF02492.19 KXS11950.1 - 0.018 14.7 0.1 0.99 9.0 0.0 2.8 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 KXS11950.1 - 0.019 15.1 0.0 2.4 8.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 KXS11950.1 - 0.02 14.7 0.0 11 5.7 0.0 3.3 4 0 0 4 4 3 0 Ethanolamine utilisation - propanediol utilisation Adeno_IVa2 PF02456.15 KXS11950.1 - 0.021 13.6 0.1 0.21 10.3 0.0 2.0 2 0 0 2 2 2 0 Adenovirus IVa2 protein MCM PF00493.23 KXS11950.1 - 0.042 12.9 0.0 0.12 11.5 0.0 1.7 2 0 0 2 2 2 0 MCM P-loop domain Ploopntkinase3 PF18751.1 KXS11950.1 - 0.058 13.3 0.0 3.9 7.4 0.0 2.2 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 Pox_A32 PF04665.12 KXS11950.1 - 0.065 12.7 0.0 1.1 8.7 0.0 2.1 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_23 PF13476.6 KXS11950.1 - 0.071 13.6 0.1 1.6 9.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 KXS11950.1 - 0.073 12.3 0.0 13 4.9 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain OKR_DC_1_N PF03709.15 KXS11950.1 - 0.076 13.3 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, N-terminal domain SPARC_Ca_bdg PF10591.9 KXS11950.1 - 0.096 13.0 0.4 1.6 9.1 0.0 2.5 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region TsaE PF02367.17 KXS11950.1 - 0.11 12.5 0.0 18 5.4 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 KXS11950.1 - 0.12 11.6 0.0 11 5.2 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin TrwB_AAD_bind PF10412.9 KXS11950.1 - 0.17 10.7 0.0 3.9 6.3 0.0 2.1 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain G-alpha PF00503.20 KXS11950.1 - 0.2 10.8 0.0 25 3.9 0.0 2.7 3 0 0 3 3 3 0 G-protein alpha subunit Arm PF00514.23 KXS11951.1 - 1.2e-87 285.6 21.1 6.8e-12 45.0 0.0 8.7 9 0 0 9 9 9 8 Armadillo/beta-catenin-like repeat Arm_3 PF16186.5 KXS11951.1 - 6e-24 83.4 1.9 4.9e-23 80.4 1.5 2.3 2 0 0 2 2 2 1 Atypical Arm repeat IBB PF01749.20 KXS11951.1 - 3.9e-23 81.7 2.9 1e-22 80.4 2.9 1.8 1 0 0 1 1 1 1 Importin beta binding domain HEAT_EZ PF13513.6 KXS11951.1 - 4.4e-18 65.4 4.0 4.4e-08 33.4 0.1 6.3 4 2 2 6 6 6 4 HEAT-like repeat HEAT_2 PF13646.6 KXS11951.1 - 3.7e-16 59.3 3.3 3.8e-08 33.6 0.1 5.0 3 2 2 5 5 5 4 HEAT repeats HEAT PF02985.22 KXS11951.1 - 4e-16 57.7 0.1 8.2e-06 25.7 0.0 6.6 6 0 0 6 6 6 3 HEAT repeat V-ATPase_H_C PF11698.8 KXS11951.1 - 1.7e-05 24.9 0.0 0.41 10.8 0.0 4.0 3 1 2 5 5 5 3 V-ATPase subunit H Arm_2 PF04826.13 KXS11951.1 - 7.1e-05 22.4 0.1 1.9 7.9 0.0 4.1 2 1 2 4 4 4 2 Armadillo-like RICTOR_V PF14668.6 KXS11951.1 - 0.0015 18.7 1.5 0.07 13.4 0.0 3.7 4 1 1 5 5 5 1 Rapamycin-insensitive companion of mTOR, domain 5 HEAT_PBS PF03130.16 KXS11951.1 - 0.0081 16.7 3.5 0.46 11.3 0.2 4.5 4 0 0 4 4 4 1 PBS lyase HEAT-like repeat Atx10homo_assoc PF09759.9 KXS11951.1 - 0.011 15.8 0.2 0.34 10.9 0.0 3.2 2 1 1 3 3 3 0 Spinocerebellar ataxia type 10 protein domain Myosin_head PF00063.21 KXS11953.1 - 2.1e-256 852.4 0.5 2.1e-256 852.4 0.5 3.2 2 1 0 2 2 2 1 Myosin head (motor domain) Myosin_tail_1 PF01576.19 KXS11953.1 - 2.1e-92 310.6 360.0 5.5e-71 239.8 219.8 4.3 1 1 3 4 4 4 4 Myosin tail Ribosomal_S11 PF00411.19 KXS11953.1 - 1.5e-45 154.1 1.9 4.8e-45 152.5 1.4 2.1 2 0 0 2 2 2 1 Ribosomal protein S11 Myosin_N PF02736.19 KXS11953.1 - 1.3e-11 44.1 0.8 3.3e-11 42.8 0.8 1.7 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain HALZ PF02183.18 KXS11953.1 - 0.00057 20.0 1.0 0.00057 20.0 1.0 16.2 18 1 0 18 18 18 1 Homeobox associated leucine zipper BRE1 PF08647.11 KXS11953.1 - 0.0008 19.4 6.6 0.0008 19.4 6.6 17.6 3 3 15 20 20 20 3 BRE1 E3 ubiquitin ligase IQ PF00612.27 KXS11953.1 - 0.0014 18.2 7.9 0.0018 17.9 2.4 2.9 2 0 0 2 2 2 1 IQ calmodulin-binding motif Erf4 PF10256.9 KXS11953.1 - 0.09 12.9 1.1 0.67 10.1 0.0 3.2 3 0 0 3 3 3 0 Golgin subfamily A member 7/ERF4 family AAA_22 PF13401.6 KXS11953.1 - 0.54 10.5 0.0 0.54 10.5 0.0 6.1 7 1 1 8 8 8 0 AAA domain Pescadillo_N PF06732.11 KXS11955.1 - 1.2e-84 284.1 1.0 1.5e-84 283.8 0.0 1.6 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT_2 PF16589.5 KXS11955.1 - 0.0013 19.1 0.0 0.0026 18.1 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain YL1 PF05764.13 KXS11955.1 - 0.0044 17.2 22.9 0.0078 16.4 22.9 1.3 1 0 0 1 1 1 1 YL1 nuclear protein Mem_trans PF03547.18 KXS11956.1 - 1.6e-17 63.0 7.7 3.2e-16 58.7 7.7 2.5 1 1 0 1 1 1 1 Membrane transport protein Alk_phosphatase PF00245.20 KXS11957.1 - 3.9e-59 200.7 0.0 1.2e-58 199.0 0.0 1.7 1 1 0 1 1 1 1 Alkaline phosphatase Herpes_UL35 PF04496.12 KXS11957.1 - 0.15 12.4 0.1 2.3 8.5 0.0 2.4 2 0 0 2 2 2 0 Herpesvirus UL35 family DUF4107 PF13389.6 KXS11958.1 - 0.14 12.3 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4107) SH3_9 PF14604.6 KXS11960.1 - 0.0002 21.2 0.0 0.00039 20.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain DUF3827 PF12877.7 KXS11960.1 - 0.0022 16.5 0.0 0.0027 16.2 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3827) EphA2_TM PF14575.6 KXS11960.1 - 0.0033 18.3 0.0 0.0043 17.9 0.0 1.3 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Miga PF10265.9 KXS11960.1 - 0.018 14.0 0.0 0.022 13.7 0.0 1.0 1 0 0 1 1 1 0 Mitoguardin SH3_1 PF00018.28 KXS11960.1 - 0.032 13.8 0.0 0.057 13.0 0.0 1.4 1 0 0 1 1 1 0 SH3 domain Pkinase_Tyr PF07714.17 KXS11961.1 - 1.4e-11 44.1 0.0 2e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXS11961.1 - 2.9e-09 36.7 0.0 7.1e-09 35.4 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Sel1 PF08238.12 KXS11962.1 - 3.3e-113 367.6 77.4 1.2e-09 38.5 0.2 15.6 15 1 0 15 15 15 15 Sel1 repeat Pkinase_Tyr PF07714.17 KXS11962.1 - 1.6e-14 53.9 0.1 2.2e-14 53.4 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXS11962.1 - 1.3e-12 47.6 0.1 2e-12 47.1 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain DUF977 PF06163.11 KXS11962.1 - 0.00059 19.8 16.1 2.5 8.1 0.2 6.8 2 2 4 7 7 7 2 Bacterial protein of unknown function (DUF977) TPR_6 PF13174.6 KXS11962.1 - 0.0027 18.2 7.9 1.2e+02 3.7 0.0 8.6 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_12 PF13424.6 KXS11962.1 - 0.064 13.5 18.8 6.8 7.1 0.1 7.8 6 2 1 7 7 7 0 Tetratricopeptide repeat TPR_7 PF13176.6 KXS11962.1 - 0.19 11.8 0.9 2.7 8.2 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 KXS11962.1 - 0.37 10.5 30.2 0.11 12.2 1.5 8.5 9 0 0 9 9 9 0 TPR repeat RIG-I_C PF18119.1 KXS11962.1 - 0.74 9.8 9.6 4.6 7.3 0.2 4.5 4 1 1 5 5 5 0 RIG-I receptor C-terminal domain Neur_chan_memb PF02932.16 KXS11964.1 - 0.094 12.8 0.4 0.17 11.9 0.4 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Gram_pos_anchor PF00746.21 KXS11964.1 - 4.8 7.2 5.2 0.79 9.7 0.2 2.2 2 0 0 2 2 2 0 LPXTG cell wall anchor motif SNF2_N PF00176.23 KXS11965.1 - 2.6e-35 121.8 0.0 4.4e-34 117.7 0.0 2.6 2 1 0 2 2 2 1 SNF2 family N-terminal domain zf-RING_2 PF13639.6 KXS11965.1 - 9.6e-10 38.6 8.8 2.2e-09 37.5 8.8 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KXS11965.1 - 1.2e-08 34.7 6.6 2.6e-08 33.6 6.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXS11965.1 - 2.7e-08 33.5 9.3 4.9e-08 32.7 9.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Helicase_C PF00271.31 KXS11965.1 - 9.3e-08 32.4 0.6 2.9e-07 30.8 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Prok-RING_4 PF14447.6 KXS11965.1 - 1.1e-06 28.4 7.6 2.1e-06 27.5 7.6 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KXS11965.1 - 3.1e-06 27.0 10.3 6.5e-06 25.9 10.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KXS11965.1 - 3.7e-06 27.1 7.6 9.7e-06 25.8 7.6 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KXS11965.1 - 1e-05 25.4 6.3 2.4e-05 24.3 6.3 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KXS11965.1 - 8.3e-05 22.5 8.3 0.00018 21.4 8.3 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 KXS11965.1 - 0.0011 19.0 2.1 0.0023 18.0 2.1 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.6 KXS11965.1 - 0.0046 16.8 1.8 0.011 15.6 1.8 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein ResIII PF04851.15 KXS11965.1 - 0.052 13.6 0.0 0.28 11.2 0.0 2.2 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit Wtap PF17098.5 KXS11965.1 - 0.084 12.8 7.7 1.3 9.0 0.9 2.5 2 0 0 2 2 2 0 WTAP/Mum2p family Zn_ribbon_17 PF17120.5 KXS11965.1 - 0.085 12.5 6.2 0.17 11.5 6.2 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 KXS11965.1 - 0.12 12.6 10.7 0.25 11.5 10.7 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 KXS11965.1 - 0.19 11.9 2.9 0.45 10.7 2.9 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_11 PF17123.5 KXS11965.1 - 0.86 9.4 6.8 2.1 8.1 6.8 1.7 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_4 PF14570.6 KXS11965.1 - 3.8 7.4 7.5 8.5 6.3 7.5 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DivIC PF04977.15 KXS11965.1 - 4 7.3 5.7 18 5.2 0.5 2.6 1 1 1 2 2 2 0 Septum formation initiator DIOX_N PF14226.6 KXS11966.1 - 4.1e-25 88.8 0.0 9.1e-25 87.7 0.0 1.6 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KXS11966.1 - 5.4e-19 68.5 0.0 1.1e-18 67.5 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily p450 PF00067.22 KXS11967.1 - 5.9e-64 216.5 0.0 1.1e-63 215.6 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 DUF2953 PF11167.8 KXS11967.1 - 0.14 12.3 0.5 16 5.7 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2953) 2_5_RNA_ligase2 PF13563.6 KXS11968.1 - 3.8e-33 114.6 1.1 2.9e-32 111.7 0.7 2.4 2 0 0 2 2 2 1 2'-5' RNA ligase superfamily MJ1316 PF04457.12 KXS11968.1 - 1.9e-18 66.9 0.1 4.1e-18 65.9 0.1 1.6 1 0 0 1 1 1 1 MJ1316 RNA cyclic group end recognition domain PAP_central PF04928.17 KXS11968.1 - 1.9e-13 50.0 0.0 3.2e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 Poly(A) polymerase central domain Exo_endo_phos PF03372.23 KXS11968.1 - 4.4e-11 42.8 0.1 3.4e-10 39.8 0.1 2.4 2 1 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family NTP_transf_2 PF01909.23 KXS11968.1 - 0.00079 19.7 0.0 0.0019 18.4 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain NAD_binding_10 PF13460.6 KXS11969.1 - 0.048 13.6 0.0 0.092 12.6 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding DOPA_dioxygen PF08883.11 KXS11970.1 - 3.2e-16 59.5 1.2 4.5e-16 59.0 1.2 1.2 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family Ank_2 PF12796.7 KXS11971.1 - 0.025 15.2 0.0 0.18 12.4 0.0 2.2 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) SH3_2 PF07653.17 KXS11971.1 - 0.09 12.5 0.0 5 6.9 0.0 2.9 2 0 0 2 2 2 0 Variant SH3 domain ATG16 PF08614.11 KXS11971.1 - 0.097 12.9 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Ank_4 PF13637.6 KXS11971.1 - 0.13 12.8 0.0 4.9 7.9 0.0 2.6 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXS11971.1 - 0.14 12.8 0.0 22 6.0 0.0 2.9 2 0 0 2 2 2 0 Ankyrin repeat DUF1192 PF06698.11 KXS11971.1 - 6.2 7.0 11.0 18 5.5 1.4 3.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1192) F-box-like PF12937.7 KXS11972.1 - 0.00027 20.8 3.1 0.0018 18.1 3.1 2.3 1 1 0 1 1 1 1 F-box-like FAD_binding_4 PF01565.23 KXS11973.1 - 3.1e-19 69.1 4.0 3.1e-19 69.1 4.0 1.6 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 KXS11973.1 - 6.3e-11 42.2 0.1 1.2e-10 41.3 0.1 1.4 1 0 0 1 1 1 1 Berberine and berberine like F-box-like PF12937.7 KXS11974.1 - 0.013 15.4 0.3 0.029 14.3 0.3 1.7 1 1 0 1 1 1 0 F-box-like F-box PF00646.33 KXS11974.1 - 0.038 13.9 0.5 1.8 8.5 0.2 2.6 1 1 1 2 2 2 0 F-box domain Methyltransf_23 PF13489.6 KXS11976.1 - 2.9e-25 89.0 0.0 3.6e-25 88.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXS11976.1 - 3e-14 53.4 0.0 8.1e-14 52.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXS11976.1 - 1.3e-11 45.0 0.0 3.9e-10 40.3 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXS11976.1 - 6.6e-11 42.0 0.0 3.3e-10 39.7 0.0 1.9 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KXS11976.1 - 2e-07 31.7 0.0 3.7e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXS11976.1 - 8.3e-06 25.7 0.0 1.5e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ank_2 PF12796.7 KXS11977.1 - 4.2e-16 59.3 1.4 6.5e-06 26.6 0.0 3.7 2 1 1 4 4 4 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXS11977.1 - 2.3e-09 36.7 10.9 0.28 11.9 0.0 7.6 9 0 0 9 9 9 3 Ankyrin repeat Ank_5 PF13857.6 KXS11977.1 - 5.6e-05 23.3 8.1 5.5 7.4 0.0 6.0 4 2 2 6 6 6 2 Ankyrin repeats (many copies) Ank PF00023.30 KXS11977.1 - 0.00068 20.0 14.0 2.9 8.5 0.0 6.1 7 0 0 7 7 7 3 Ankyrin repeat Ank_4 PF13637.6 KXS11977.1 - 0.00083 19.9 5.6 0.91 10.2 0.0 5.2 5 3 1 6 6 6 2 Ankyrin repeats (many copies) DBD_HTH PF18430.1 KXS11977.1 - 0.015 15.1 0.1 0.03 14.1 0.1 1.5 1 0 0 1 1 1 0 Putative DNA-binding domain Syntaxin PF00804.25 KXS11979.1 - 3.8e-21 75.7 0.2 8e-21 74.6 0.0 1.5 2 0 0 2 2 2 1 Syntaxin SNARE PF05739.19 KXS11979.1 - 2.3e-05 24.3 3.3 2.3e-05 24.3 3.3 2.6 3 1 0 3 3 3 1 SNARE domain DUF3827 PF12877.7 KXS11979.1 - 0.0089 14.5 1.5 0.012 14.1 0.8 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3827) RHH_6 PF16762.5 KXS11979.1 - 0.02 15.5 1.0 0.2 12.3 0.1 2.5 2 0 0 2 2 2 0 Ribbon-helix-helix domain Syntaxin_2 PF14523.6 KXS11979.1 - 0.021 15.2 0.0 0.12 12.8 0.0 2.1 2 0 0 2 2 2 0 Syntaxin-like protein IZUMO PF15005.6 KXS11979.1 - 0.15 12.6 0.1 0.42 11.1 0.0 1.8 2 0 0 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated UPF0149 PF03695.13 KXS11979.1 - 0.31 11.3 3.4 0.83 9.9 0.1 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0149) NPV_P10 PF05531.12 KXS11979.1 - 0.65 10.5 2.7 7.4 7.1 0.1 3.0 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein PMEI PF04043.15 KXS11979.1 - 0.88 9.9 7.2 0.64 10.4 1.5 2.1 1 1 1 2 2 2 0 Plant invertase/pectin methylesterase inhibitor 7TMR-HDED PF07697.11 KXS11979.1 - 2.6 8.1 11.2 2.7e+02 1.5 11.2 2.1 1 1 0 1 1 1 0 7TM-HD extracellular TetR_C_11 PF16859.5 KXS11979.1 - 3 8.2 12.6 1.3 9.4 1.6 3.1 2 1 1 3 3 3 0 Tetracyclin repressor-like, C-terminal domain DUF2277 PF10041.9 KXS11979.1 - 7.4 7.0 7.8 22 5.5 0.1 4.3 3 2 2 5 5 5 0 Uncharacterized conserved protein (DUF2277) F-box-like PF12937.7 KXS11980.1 - 1.3e-08 34.6 0.0 2.1e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXS11980.1 - 6e-05 22.8 0.0 0.0001 22.0 0.0 1.4 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KXS11980.1 - 0.11 12.4 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 F-box Reprolysin_5 PF13688.6 KXS11981.1 - 0.052 13.7 0.1 0.093 12.9 0.1 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12 RXT2_N PF08595.11 KXS11982.1 - 0.057 13.5 3.5 0.068 13.2 3.5 1.1 1 0 0 1 1 1 0 RXT2-like, N-terminal Pox_Ag35 PF03286.14 KXS11982.1 - 0.084 12.7 2.6 0.092 12.5 2.6 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CENP-B_dimeris PF09026.10 KXS11982.1 - 0.088 13.2 12.9 0.12 12.8 12.9 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain FAM176 PF14851.6 KXS11982.1 - 0.088 12.5 1.7 0.11 12.2 1.7 1.2 1 0 0 1 1 1 0 FAM176 family CTU2 PF10288.9 KXS11982.1 - 0.26 11.6 2.6 0.56 10.5 2.6 1.6 1 1 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 Cwf_Cwc_15 PF04889.12 KXS11982.1 - 0.26 11.0 10.8 0.3 10.8 10.8 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein YL1 PF05764.13 KXS11982.1 - 0.54 10.3 4.8 0.58 10.2 4.8 1.1 1 0 0 1 1 1 0 YL1 nuclear protein TNFR_c6 PF00020.18 KXS11982.1 - 0.58 10.6 6.1 0.63 10.5 2.3 2.1 2 0 0 2 2 2 0 TNFR/NGFR cysteine-rich region zf-C2H2_7 PF15269.6 KXS11982.1 - 0.97 9.6 0.1 0.97 9.6 0.1 2.4 2 1 0 2 2 2 0 Zinc-finger BUD22 PF09073.10 KXS11982.1 - 0.98 8.7 5.2 1 8.6 5.2 1.0 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 KXS11982.1 - 1.1 7.3 7.4 1.3 7.2 7.4 1.0 1 0 0 1 1 1 0 Nop14-like family DUF3295 PF11702.8 KXS11982.1 - 2 7.7 5.0 2.2 7.5 5.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) PBP1_TM PF14812.6 KXS11982.1 - 2.1 8.8 13.4 3.7 8.0 13.4 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sporozoite_P67 PF05642.11 KXS11982.1 - 2.8 5.9 5.0 3.2 5.7 5.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF2457 PF10446.9 KXS11982.1 - 3.8 6.6 17.7 4.4 6.3 17.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF4611 PF15387.6 KXS11982.1 - 5.8 7.2 10.7 8.5 6.7 10.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Sigma70_ner PF04546.13 KXS11982.1 - 6.7 6.5 9.7 8.4 6.2 9.7 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region CDC45 PF02724.14 KXS11982.1 - 6.9 4.8 7.7 7.4 4.7 7.7 1.0 1 0 0 1 1 1 0 CDC45-like protein C1_2 PF03107.16 KXS11982.1 - 6.9 7.1 9.8 19 5.7 1.1 3.2 2 1 1 3 3 3 0 C1 domain zf-CCHC_2 PF13696.6 KXS11982.1 - 8.7 6.3 12.0 3 7.8 0.5 3.0 3 0 0 3 3 3 0 Zinc knuckle RRN3 PF05327.11 KXS11982.1 - 9.3 4.7 7.2 10 4.5 7.2 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DSPc PF00782.20 KXS11983.1 - 1.7e-26 92.6 0.0 2.1e-26 92.3 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KXS11983.1 - 0.00094 18.8 0.0 0.0012 18.5 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 KXS11983.1 - 0.066 13.3 0.0 0.094 12.8 0.0 1.2 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase2 PF03162.13 KXS11983.1 - 0.13 11.8 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family SET PF00856.28 KXS11984.1 - 5.6e-05 23.6 2.0 0.004 17.6 0.0 3.4 2 2 0 2 2 2 1 SET domain zf-MYND PF01753.18 KXS11984.1 - 0.0034 17.4 1.5 0.0034 17.4 1.5 2.7 3 0 0 3 3 3 1 MYND finger BSP_II PF05432.11 KXS11984.1 - 0.0036 17.1 11.5 0.0057 16.4 11.5 1.2 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) TPR_12 PF13424.6 KXS11984.1 - 0.012 15.9 0.0 0.034 14.4 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_10 PF13374.6 KXS11984.1 - 0.054 13.4 0.1 0.19 11.6 0.1 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat Ecl1 PF12855.7 KXS11984.1 - 0.19 12.8 0.4 0.19 12.8 0.4 2.4 3 0 0 3 3 3 0 ECL1/2/3 zinc binding proteins Rotamase PF00639.21 KXS11984.1 - 0.23 12.5 0.9 0.69 10.9 0.9 1.8 1 0 0 1 1 1 0 PPIC-type PPIASE domain zf-FCS PF06467.14 KXS11984.1 - 0.94 9.5 6.7 17 5.4 0.0 3.1 2 1 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zf-B_box PF00643.24 KXS11985.1 - 4.8e-09 36.2 8.9 4.8e-09 36.2 8.9 2.6 2 1 0 2 2 2 1 B-box zinc finger zf-C3HC4_3 PF13920.6 KXS11985.1 - 0.00011 21.9 10.3 0.00011 21.9 10.3 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXS11985.1 - 0.00043 20.5 12.5 0.00043 20.5 12.5 2.1 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 KXS11985.1 - 0.0012 18.6 12.6 0.0012 18.6 12.6 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 KXS11985.1 - 0.14 12.1 5.8 0.45 10.4 5.8 1.9 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Rad50_zn_hook PF04423.14 KXS11985.1 - 0.21 11.5 2.0 1.6 8.6 0.3 2.7 2 0 0 2 2 2 0 Rad50 zinc hook motif Zn_ribbon_17 PF17120.5 KXS11985.1 - 2.7 7.7 14.0 0.15 11.7 7.5 2.0 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-UDP PF14569.6 KXS11985.1 - 5.2 7.3 8.4 23 5.2 2.7 2.4 2 0 0 2 2 2 0 Zinc-binding RING-finger Methyltransf_16 PF10294.9 KXS11986.1 - 2.6e-19 69.6 0.0 6.7e-19 68.3 0.0 1.7 1 1 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 KXS11986.1 - 8.8e-05 22.4 0.0 0.00017 21.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Na_Pi_cotrans PF02690.15 KXS11986.1 - 0.045 13.8 0.3 0.077 13.1 0.3 1.2 1 0 0 1 1 1 0 Na+/Pi-cotransporter MTS PF05175.14 KXS11986.1 - 0.075 12.6 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Peptidase_M36 PF02128.15 KXS11987.1 - 0.0087 15.3 0.1 0.013 14.6 0.1 1.3 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) Acetyltransf_1 PF00583.25 KXS11988.1 - 4.1e-10 39.9 0.0 3.4e-09 37.0 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXS11988.1 - 1.8e-09 37.9 0.0 3.2e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KXS11988.1 - 1.1e-07 31.8 0.0 8.4e-07 29.0 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXS11988.1 - 0.00028 20.8 0.0 0.0016 18.3 0.0 2.1 1 1 0 1 1 1 1 FR47-like protein PanZ PF12568.8 KXS11988.1 - 0.00063 19.5 0.4 0.0011 18.7 0.1 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_3 PF13302.7 KXS11988.1 - 0.0012 19.5 0.0 0.0023 18.6 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KXS11988.1 - 0.016 15.3 0.0 0.027 14.6 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_13 PF13880.6 KXS11988.1 - 0.08 12.9 0.1 0.31 11.0 0.1 1.9 2 0 0 2 2 2 0 ESCO1/2 acetyl-transferase HMD PF03201.16 KXS11988.1 - 0.18 12.0 1.7 0.31 11.3 1.7 1.3 1 0 0 1 1 1 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase DUF389 PF04087.14 KXS11988.1 - 0.51 10.4 7.5 0.87 9.6 7.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF389) Ank_2 PF12796.7 KXS11990.1 - 0.00016 22.2 0.0 0.64 10.7 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXS11990.1 - 0.0051 17.2 0.0 0.55 11.0 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeat Mon2_C PF16206.5 KXS11990.1 - 0.063 11.4 0.0 0.071 11.2 0.0 1.0 1 0 0 1 1 1 0 C-terminal region of Mon2 protein Ank_5 PF13857.6 KXS11990.1 - 0.16 12.3 0.0 2 8.9 0.0 2.1 2 0 0 2 2 2 0 Ankyrin repeats (many copies) PB1 PF00564.24 KXS11991.1 - 5.4e-08 32.7 0.0 9.9e-08 31.8 0.0 1.3 1 0 0 1 1 1 1 PB1 domain Calycin_like PF13944.6 KXS11991.1 - 0.31 11.4 3.7 0.12 12.7 0.4 1.9 2 0 0 2 2 2 0 Calycin-like beta-barrel domain Nucleo_P87 PF07267.11 KXS11992.1 - 0.055 12.3 1.7 0.061 12.2 1.7 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Presenilin PF01080.17 KXS11992.1 - 9.5 4.9 6.2 11 4.7 6.2 1.2 1 0 0 1 1 1 0 Presenilin TPR_10 PF13374.6 KXS11993.1 - 0.044 13.7 1.8 5.4 7.0 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Orf78 PF06024.12 KXS11994.1 - 0.18 12.1 0.0 0.31 11.3 0.0 1.3 1 0 0 1 1 1 0 Orf78 (ac78) Phosphodiest PF01663.22 KXS11995.1 - 1.7e-78 264.7 0.0 2e-78 264.5 0.0 1.0 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KXS11995.1 - 4.8e-05 22.9 0.1 0.2 11.0 0.0 2.3 2 1 0 2 2 2 2 Sulfatase Metalloenzyme PF01676.18 KXS11995.1 - 0.027 13.8 0.0 0.047 13.1 0.0 1.3 1 0 0 1 1 1 0 Metalloenzyme superfamily PglZ PF08665.12 KXS11995.1 - 0.21 11.7 0.0 0.39 10.8 0.0 1.3 1 0 0 1 1 1 0 PglZ domain DLH PF01738.18 KXS11997.1 - 8.3e-16 58.2 0.0 1.1e-15 57.8 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 KXS11997.1 - 0.016 14.9 0.0 0.025 14.2 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Rhodanese PF00581.20 KXS11998.1 - 4.3e-11 43.3 0.0 6.9e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain PAF-AH_p_II PF03403.13 KXS11999.1 - 7.8e-53 179.3 0.0 3.1e-52 177.4 0.0 2.0 1 1 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 KXS11999.1 - 2.8e-08 33.0 0.1 8.2e-05 21.6 0.0 2.5 2 1 0 2 2 2 2 Chlorophyllase enzyme Chlorophyllase PF07224.11 KXS11999.1 - 0.00018 20.6 0.0 0.015 14.3 0.0 2.9 3 0 0 3 3 3 1 Chlorophyllase Hydrolase_4 PF12146.8 KXS11999.1 - 0.00056 19.3 0.4 0.35 10.1 0.1 2.7 3 0 0 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KXS11999.1 - 0.025 14.3 0.3 0.11 12.1 0.3 2.1 1 1 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KXS11999.1 - 0.027 13.9 0.0 0.059 12.8 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family Radical_SAM PF04055.21 KXS12000.1 - 2e-11 44.6 0.1 1.3e-10 41.9 0.1 2.2 1 1 0 1 1 1 1 Radical SAM superfamily HemN_C PF06969.16 KXS12000.1 - 8.1e-06 25.8 0.0 1.5e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 HemN C-terminal domain Cyclin_N PF00134.23 KXS12003.1 - 3.5e-12 46.2 0.2 4.2e-12 45.9 0.2 1.1 1 0 0 1 1 1 1 Cyclin, N-terminal domain Defensin_propep PF00879.18 KXS12003.1 - 0.34 11.2 2.4 0.73 10.1 2.4 1.5 1 0 0 1 1 1 0 Defensin propeptide PDZ_3 PF17815.1 KXS12004.1 - 1.9e-27 95.9 0.0 3.3e-27 95.1 0.0 1.3 1 0 0 1 1 1 1 PDZ domain Trypsin_2 PF13365.6 KXS12004.1 - 5.4e-21 76.1 0.7 1.1e-20 75.0 0.3 1.8 2 0 0 2 2 2 1 Trypsin-like peptidase domain Trypsin PF00089.26 KXS12004.1 - 6.3e-15 55.6 0.1 1.1e-14 54.8 0.1 1.3 1 0 0 1 1 1 1 Trypsin PDZ_2 PF13180.6 KXS12004.1 - 3.3e-05 24.1 0.0 0.0029 17.9 0.0 2.8 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 KXS12004.1 - 0.00027 20.7 0.0 0.49 10.3 0.0 2.7 2 0 0 2 2 2 2 PDZ domain Peptidase_S46 PF10459.9 KXS12004.1 - 0.0011 17.8 1.0 0.14 10.7 0.1 2.1 2 0 0 2 2 2 2 Peptidase S46 PDZ PF00595.24 KXS12004.1 - 0.012 15.9 0.0 0.097 13.0 0.0 2.3 2 0 0 2 2 2 0 PDZ domain DUF1604 PF07713.13 KXS12005.1 - 0.0049 16.6 1.1 0.016 15.0 0.9 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1604) ERG2_Sigma1R PF04622.12 KXS12007.1 - 2.3e-65 219.8 0.5 2.8e-65 219.6 0.5 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein ScsC_N PF18312.1 KXS12007.1 - 0.19 11.5 0.0 0.4 10.5 0.0 1.5 1 0 0 1 1 1 0 Copper resistance protein ScsC N-terminal domain zf-GRF PF06839.12 KXS12008.1 - 4.8e-06 26.6 8.6 7.2e-06 26.0 8.6 1.3 1 0 0 1 1 1 1 GRF zinc finger He_PIG PF05345.12 KXS12009.1 - 0.0021 18.2 0.0 0.0021 18.2 0.0 3.5 3 0 0 3 3 3 1 Putative Ig domain Gram_pos_anchor PF00746.21 KXS12009.1 - 0.34 10.9 2.4 1 9.4 2.4 1.8 1 0 0 1 1 1 0 LPXTG cell wall anchor motif AJAP1_PANP_C PF15298.6 KXS12009.1 - 0.47 10.6 14.0 0.45 10.7 0.9 2.3 2 0 0 2 2 2 0 AJAP1/PANP C-terminus Abhydrolase_2 PF02230.16 KXS12010.1 - 5.7e-66 222.4 0.0 6.9e-66 222.2 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase FSH1 PF03959.13 KXS12010.1 - 4.9e-09 36.2 0.0 1.5e-08 34.6 0.0 1.7 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Hydrolase_4 PF12146.8 KXS12010.1 - 2.2e-08 33.7 0.5 0.00063 19.1 0.0 3.1 2 1 1 3 3 3 3 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KXS12010.1 - 7.3e-08 33.3 0.9 2.6e-07 31.5 0.5 1.6 1 1 1 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KXS12010.1 - 5.3e-06 26.1 0.9 0.0002 20.9 0.0 2.3 2 1 1 3 3 3 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 KXS12010.1 - 4.8e-05 23.3 0.2 0.1 12.4 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold DLH PF01738.18 KXS12010.1 - 0.00013 21.6 0.0 0.00018 21.1 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 KXS12010.1 - 0.0067 16.1 3.1 1.1 8.8 0.3 2.9 2 1 1 3 3 3 1 alpha/beta hydrolase fold LIP PF03583.14 KXS12010.1 - 0.013 14.8 0.0 0.23 10.8 0.0 2.1 2 0 0 2 2 2 0 Secretory lipase Esterase PF00756.20 KXS12010.1 - 0.031 13.9 0.0 0.036 13.7 0.0 1.2 1 0 0 1 1 1 0 Putative esterase Lipase_3 PF01764.25 KXS12010.1 - 0.069 13.0 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Cutinase PF01083.22 KXS12010.1 - 0.21 11.5 0.0 0.32 10.9 0.0 1.3 1 0 0 1 1 1 0 Cutinase Abhydrolase_1 PF00561.20 KXS12011.1 - 3.8e-22 79.2 0.0 2e-16 60.4 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXS12011.1 - 4.4e-21 76.5 0.1 6.5e-21 75.9 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXS12011.1 - 9e-13 48.0 0.0 3.1e-12 46.3 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 EHN PF06441.12 KXS12011.1 - 0.012 16.0 0.0 0.023 15.1 0.0 1.5 1 0 0 1 1 1 0 Epoxide hydrolase N terminus FSH1 PF03959.13 KXS12011.1 - 0.02 14.6 0.0 0.3 10.7 0.0 2.2 2 0 0 2 2 2 0 Serine hydrolase (FSH1) FHA PF00498.26 KXS12012.1 - 2.5e-14 53.4 0.0 7e-14 51.9 0.0 1.8 2 0 0 2 2 2 1 FHA domain zf-RING_11 PF17123.5 KXS12012.1 - 6.4e-10 38.6 12.8 1.4e-09 37.5 12.8 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 KXS12012.1 - 1.3e-05 25.5 13.1 2.1e-05 24.8 13.1 1.4 1 0 0 1 1 1 1 Ring finger domain Yop-YscD_cpl PF16697.5 KXS12012.1 - 9.7e-05 22.6 0.0 0.00022 21.4 0.0 1.5 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain zf-ANAPC11 PF12861.7 KXS12012.1 - 0.054 13.6 5.5 0.095 12.8 5.5 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 KXS12012.1 - 0.37 10.8 13.6 0.68 9.9 13.6 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.25 KXS12012.1 - 1.1 9.1 14.0 1.9 8.4 14.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KXS12012.1 - 1.2 9.5 9.0 2.8 8.3 9.0 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KXS12012.1 - 6.1 6.8 14.9 11 5.9 14.9 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 KXS12012.1 - 6.5 6.7 11.8 12 5.9 11.8 1.5 1 0 0 1 1 1 0 PHD-finger Mg_trans_NIPA PF05653.14 KXS12013.1 - 1.9e-20 73.2 10.4 1.6e-18 66.9 8.5 2.9 2 1 0 2 2 2 2 Magnesium transporter NIPA TBPIP PF07106.13 KXS12014.1 - 2.3e-19 69.1 0.3 3.8e-19 68.4 0.3 1.4 1 0 0 1 1 1 1 TBPIP/Hop2 winged helix domain TFIIE_beta PF02186.15 KXS12014.1 - 0.003 17.8 1.8 0.011 16.0 0.1 2.4 3 0 0 3 3 3 1 TFIIE beta subunit core domain Penicillinase_R PF03965.16 KXS12014.1 - 0.0061 16.9 0.5 0.011 16.1 0.5 1.4 1 0 0 1 1 1 1 Penicillinase repressor DUF4140 PF13600.6 KXS12014.1 - 0.24 11.8 3.7 0.13 12.7 1.2 1.9 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) zf-CCCH PF00642.24 KXS12015.1 - 2.1e-19 68.9 11.8 3.5e-10 39.5 5.1 2.1 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KXS12015.1 - 3e-10 39.8 13.0 2.6e-07 30.5 0.8 2.3 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 KXS12015.1 - 1.5e-07 31.1 9.4 0.00031 20.5 0.3 2.3 2 0 0 2 2 2 2 CCCH-type zinc finger Torus PF16131.5 KXS12015.1 - 0.003 18.2 9.1 0.06 14.0 2.1 2.1 1 1 1 2 2 2 2 Torus domain Defensin_int PF17858.1 KXS12015.1 - 0.081 12.9 2.4 0.15 12.0 0.5 2.0 2 0 0 2 2 2 0 Platypus intermediate defensin-like peptide zf-CCCH_3 PF15663.5 KXS12015.1 - 0.12 12.6 6.9 2 8.6 7.2 1.9 1 1 1 2 2 2 0 Zinc-finger containing family zf-CCCH_2 PF14608.6 KXS12015.1 - 0.17 12.4 0.3 0.17 12.4 0.3 2.6 3 1 0 3 3 3 0 RNA-binding, Nab2-type zinc finger AWS PF17907.1 KXS12015.1 - 0.52 10.4 6.4 7.1 6.8 1.7 2.3 2 0 0 2 2 2 0 AWS domain oligo_HPY PF08352.12 KXS12015.1 - 4.4 7.9 9.2 8.9 6.9 2.0 2.1 1 1 1 2 2 2 0 Oligopeptide/dipeptide transporter, C-terminal region Defensin_beta_2 PF13841.6 KXS12015.1 - 6.7 7.3 11.6 5.4 7.6 2.5 2.6 3 0 0 3 3 3 0 Beta defensin PGI PF00342.19 KXS12016.1 - 4.1e-246 817.2 0.3 4.7e-246 817.0 0.3 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase FA_hydroxylase PF04116.13 KXS12016.1 - 0.15 12.4 1.0 4.9 7.5 0.1 2.5 2 0 0 2 2 2 0 Fatty acid hydroxylase superfamily MutL_C PF08676.11 KXS12017.1 - 6e-06 26.1 0.1 0.0038 17.0 0.0 3.7 3 1 0 3 3 3 2 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 KXS12018.1 - 1.5e-11 44.0 0.2 0.00031 20.4 0.0 2.9 3 0 0 3 3 3 2 DNA mismatch repair protein, C-terminal domain HATPase_c PF02518.26 KXS12018.1 - 3.5e-10 40.4 0.1 1.4e-09 38.5 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KXS12018.1 - 4.8e-10 39.4 0.1 1.1e-09 38.3 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase OTU PF02338.19 KXS12019.1 - 8.8e-07 29.5 0.0 1.4e-06 28.9 0.0 1.2 1 0 0 1 1 1 1 OTU-like cysteine protease MSA-2c PF12238.8 KXS12019.1 - 1.7 8.6 5.8 2.6 8.0 5.8 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c Thr_synth_N PF14821.6 KXS12020.1 - 5.8e-24 84.1 0.0 1.8e-23 82.5 0.0 1.9 2 0 0 2 2 2 1 Threonine synthase N terminus PALP PF00291.25 KXS12020.1 - 3.6e-14 52.9 0.1 3.1e-13 49.8 0.1 1.9 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme VCBS PF13517.6 KXS12020.1 - 0.1 13.2 0.0 3.3 8.4 0.0 3.2 2 1 1 3 3 3 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella adh_short PF00106.25 KXS12021.1 - 0.011 15.3 0.0 0.062 12.7 0.0 1.9 1 1 0 1 1 1 0 short chain dehydrogenase adh_short PF00106.25 KXS12023.1 - 1.3e-28 99.8 0.1 2.3e-27 95.7 0.1 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXS12023.1 - 1.1e-16 61.2 0.1 1.5e-15 57.4 0.0 2.3 1 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXS12023.1 - 7.4e-08 32.5 0.1 1.4e-07 31.6 0.1 1.4 1 0 0 1 1 1 1 KR domain Pyr_redox_3 PF13738.6 KXS12023.1 - 0.1 11.8 0.1 0.15 11.3 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 KXS12023.1 - 0.12 12.2 0.4 0.22 11.4 0.1 1.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MFS_1 PF07690.16 KXS12024.1 - 2.3e-15 56.4 41.1 1.6e-10 40.5 12.6 2.7 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXS12024.1 - 8.4e-06 24.9 7.3 8.4e-06 24.9 7.3 3.2 3 1 0 3 3 3 2 Sugar (and other) transporter MFS_1_like PF12832.7 KXS12024.1 - 0.28 10.0 7.8 0.12 11.3 0.1 2.8 2 1 0 2 2 2 0 MFS_1 like family Cation_efflux PF01545.21 KXS12025.1 - 1.2e-23 83.8 3.5 1.6e-23 83.5 3.5 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KXS12025.1 - 3.4e-05 23.9 0.0 8.9e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter GPHR_N PF12537.8 KXS12025.1 - 0.067 13.3 0.0 0.18 11.9 0.0 1.7 1 0 0 1 1 1 0 The Golgi pH Regulator (GPHR) Family N-terminal Peptidase_M16 PF00675.20 KXS12027.1 - 1e-18 67.7 0.0 2.2e-18 66.7 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KXS12027.1 - 1.3e-14 54.6 0.0 2.2e-14 53.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase M16 inactive domain TFCD_C PF12612.8 KXS12028.1 - 2.4e-44 151.4 0.0 1.3e-42 145.8 0.0 3.3 2 1 0 2 2 2 1 Tubulin folding cofactor D C terminal HEAT_2 PF13646.6 KXS12028.1 - 3.1e-06 27.5 13.1 0.014 15.8 0.2 5.4 4 2 2 6 6 6 2 HEAT repeats HEAT PF02985.22 KXS12028.1 - 0.0055 16.9 19.9 0.024 14.8 0.1 7.3 8 0 0 8 8 8 2 HEAT repeat Vac14_Fab1_bd PF12755.7 KXS12028.1 - 0.019 15.6 0.0 7.8 7.2 0.0 3.6 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 KXS12028.1 - 9.7 6.8 21.1 3.2 8.4 0.1 6.3 7 0 0 7 7 7 0 HEAT-like repeat TPH PF13868.6 KXS12029.1 - 1.9e-24 85.8 109.5 1.9e-24 85.8 109.5 2.1 1 1 1 2 2 2 1 Trichohyalin-plectin-homology domain CytochromB561_N PF09786.9 KXS12029.1 - 0.51 9.3 5.6 0.47 9.4 4.0 1.7 1 1 1 2 2 2 0 Cytochrome B561, N terminal AGO_N PF18236.1 KXS12030.1 - 0.036 14.3 1.0 0.041 14.1 1.0 1.2 1 0 0 1 1 1 0 Argonaute N domain VanY PF02557.17 KXS12030.1 - 0.075 12.8 3.5 0.09 12.6 3.5 1.2 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase Sbi-IV PF11621.8 KXS12030.1 - 0.085 13.2 4.9 0.061 13.7 3.5 1.6 1 1 1 2 2 2 0 C3 binding domain 4 of IgG-bind protein SBI Zn_clus PF00172.18 KXS12032.1 - 2.9e-11 43.3 9.9 4e-11 42.8 9.9 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Thioredoxin_7 PF13899.6 KXS12032.1 - 0.026 14.7 0.6 0.073 13.3 0.0 2.0 2 0 0 2 2 2 0 Thioredoxin-like Fungal_trans PF04082.18 KXS12034.1 - 2e-16 59.8 0.0 3.5e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXS12034.1 - 2.3e-09 37.2 10.3 3.9e-09 36.5 10.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain eIF2_C PF09173.11 KXS12035.1 - 1.7e-36 124.3 1.1 2.9e-36 123.6 0.3 1.8 2 0 0 2 2 2 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 KXS12035.1 - 5e-24 84.9 0.3 2.8e-23 82.5 0.3 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 KXS12035.1 - 6.4e-14 52.1 1.2 1.8e-13 50.7 0.5 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 RsgA_GTPase PF03193.16 KXS12035.1 - 0.0011 18.9 0.5 0.011 15.6 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 KXS12035.1 - 0.0014 18.7 0.0 0.003 17.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 KXS12035.1 - 0.018 14.8 0.9 0.39 10.5 0.2 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1_Xtn PF16897.5 KXS12035.1 - 0.037 14.1 0.1 0.09 12.8 0.1 1.6 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Dynamin_N PF00350.23 KXS12035.1 - 0.12 12.5 0.1 0.55 10.3 0.0 2.1 2 1 0 2 2 2 0 Dynamin family MAGI_u5 PF16666.5 KXS12035.1 - 0.83 9.8 3.1 1.5 9.0 3.1 1.4 1 0 0 1 1 1 0 Unstructured region on MAGI CLTH PF10607.9 KXS12036.1 - 1.4e-27 96.4 0.0 3.4e-27 95.2 0.0 1.6 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.6 KXS12036.1 - 1.1e-05 25.4 0.2 2.2e-05 24.4 0.2 1.5 1 0 0 1 1 1 1 RING-type zinc-finger Rtf2 PF04641.12 KXS12036.1 - 8.5e-05 22.0 1.6 9.7e-05 21.9 0.1 1.7 2 0 0 2 2 2 1 Rtf2 RING-finger zf-C3HC4_4 PF15227.6 KXS12036.1 - 0.0028 17.8 0.9 0.0028 17.8 0.9 1.8 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 KXS12036.1 - 0.0043 17.0 0.8 0.0096 15.9 0.8 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 KXS12036.1 - 0.041 14.2 1.1 0.082 13.3 1.1 1.5 1 0 0 1 1 1 0 Ring finger domain FNIP_M PF14637.6 KXS12036.1 - 0.041 13.9 0.9 0.94 9.4 0.5 2.1 2 0 0 2 2 2 0 Folliculin-interacting protein middle domain AA_synth PF06684.11 KXS12036.1 - 0.074 12.6 0.1 12 5.4 0.0 2.3 2 0 0 2 2 2 0 Amino acid synthesis zf-C2H2_2 PF12756.7 KXS12036.1 - 0.15 12.4 2.7 1.1 9.6 0.5 2.4 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) SelR PF01641.18 KXS12037.1 - 1.7e-47 160.5 0.1 2.1e-47 160.2 0.1 1.1 1 0 0 1 1 1 1 SelR domain zf-ACC PF17848.1 KXS12037.1 - 0.044 13.9 0.7 0.94 9.6 0.0 2.4 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain zinc_ribbon_10 PF10058.9 KXS12037.1 - 0.063 13.0 0.1 1.2 8.9 0.0 2.3 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein Yippee-Mis18 PF03226.14 KXS12037.1 - 0.12 12.6 0.5 0.4 10.9 0.5 1.9 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Ribosomal_L37e PF01907.19 KXS12037.1 - 0.4 10.9 3.5 11 6.3 0.7 2.3 2 0 0 2 2 2 0 Ribosomal protein L37e zf-Mss51 PF13824.6 KXS12037.1 - 0.47 10.6 2.2 7.9 6.7 0.4 2.8 2 1 1 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 TF_Zn_Ribbon PF08271.12 KXS12037.1 - 2.1 7.9 4.9 17 5.0 0.2 2.7 3 0 0 3 3 3 0 TFIIB zinc-binding tRNA-synt_1 PF00133.22 KXS12038.1 - 4.4e-36 124.3 0.0 8.3e-22 77.2 0.0 3.7 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 KXS12038.1 - 1.6e-18 66.7 0.0 7.3e-10 38.1 0.1 2.9 2 1 0 2 2 2 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 KXS12038.1 - 3.3e-14 53.1 0.0 7.3e-14 52.0 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 KXS12038.1 - 1.2e-08 34.7 0.0 2.4e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 KXS12038.1 - 0.03 13.3 0.0 0.065 12.1 0.0 1.5 1 0 0 1 1 1 0 tRNA synthetases class I (K) G-patch PF01585.23 KXS12039.1 - 1.2e-11 44.3 0.7 2.3e-11 43.4 0.7 1.4 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KXS12039.1 - 0.0029 17.6 0.1 0.02 15.0 0.1 2.2 2 0 0 2 2 2 1 G-patch domain Aldedh PF00171.22 KXS12040.1 - 1.3e-133 445.9 0.0 1.6e-133 445.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family CGI-121 PF08617.10 KXS12041.1 - 1.6e-30 106.4 0.0 2.3e-30 105.9 0.0 1.2 1 1 0 1 1 1 1 Kinase binding protein CGI-121 2_5_RNA_ligase2 PF13563.6 KXS12042.1 - 2.7e-08 33.9 0.1 8e-05 22.6 0.0 2.4 1 1 2 3 3 3 2 2'-5' RNA ligase superfamily CPDase PF07823.11 KXS12042.1 - 9.4e-05 22.2 0.0 0.00013 21.7 0.0 1.3 1 1 0 1 1 1 1 Cyclic phosphodiesterase-like protein DSS1_SEM1 PF05160.13 KXS12043.1 - 5.9e-19 67.9 14.8 5.9e-19 67.9 14.8 1.6 2 0 0 2 2 2 1 DSS1/SEM1 family DUF2947 PF11163.8 KXS12043.1 - 0.003 17.4 6.4 0.0036 17.1 6.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2947) HisG PF01634.18 KXS12044.1 - 2.1e-53 180.5 0.0 3e-53 180.0 0.0 1.2 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 KXS12044.1 - 8.7e-28 96.3 0.0 6.4e-27 93.5 0.0 2.2 2 0 0 2 2 2 1 HisG, C-terminal domain NMT1 PF09084.11 KXS12044.1 - 9.5e-06 25.7 0.0 1.4e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 NMT1/THI5 like FAD-oxidase_C PF02913.19 KXS12045.1 - 6.6e-57 193.0 0.0 9.6e-57 192.5 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KXS12045.1 - 1.6e-36 125.1 0.7 3e-36 124.2 0.7 1.3 1 0 0 1 1 1 1 FAD binding domain DUF2642 PF10842.8 KXS12045.1 - 0.057 13.3 0.1 4.3 7.3 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2642) RRM_1 PF00076.22 KXS12046.1 - 3e-22 78.2 0.0 5.7e-14 51.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KXS12046.1 - 0.047 13.6 0.0 0.64 9.9 0.0 2.2 2 0 0 2 2 2 0 Occluded RNA-recognition motif zf-RING_2 PF13639.6 KXS12047.1 - 2.5e-06 27.7 7.8 4.7e-06 26.8 7.8 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KXS12047.1 - 0.00026 21.2 5.6 0.00052 20.2 5.6 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain FANCL_C PF11793.8 KXS12047.1 - 0.0025 18.0 4.6 0.0056 16.8 4.6 1.5 1 0 0 1 1 1 1 FANCL C-terminal domain zf-ANAPC11 PF12861.7 KXS12047.1 - 0.0029 17.6 2.6 0.0061 16.6 2.6 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING-like PF08746.11 KXS12047.1 - 0.033 14.5 7.4 0.065 13.6 7.4 1.5 1 0 0 1 1 1 0 RING-like domain zf-C3HC4 PF00097.25 KXS12047.1 - 0.044 13.7 6.6 0.083 12.8 6.6 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.7 KXS12047.1 - 0.051 13.7 6.8 0.1 12.7 6.8 1.6 1 0 0 1 1 1 0 RING-variant domain Zn_ribbon_17 PF17120.5 KXS12047.1 - 0.11 12.2 4.8 0.24 11.0 4.8 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type SelB-wing_2 PF09106.11 KXS12047.1 - 0.18 12.0 1.8 28 5.0 0.0 3.4 3 0 0 3 3 2 0 Elongation factor SelB, winged helix zf-C3HC4_2 PF13923.6 KXS12047.1 - 0.31 10.9 6.3 0.71 9.8 6.3 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) C1_1 PF00130.22 KXS12047.1 - 1.5 8.8 6.3 3.1 7.7 6.3 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Zf_RING PF16744.5 KXS12047.1 - 1.5 8.9 3.7 3.5 7.8 3.7 1.5 1 0 0 1 1 1 0 KIAA1045 RING finger zf-RING_4 PF14570.6 KXS12047.1 - 2.5 8.0 5.0 4.8 7.1 5.0 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.29 KXS12047.1 - 3.8 7.5 5.4 7.5 6.5 5.4 1.5 1 0 0 1 1 1 0 PHD-finger Ion_trans PF00520.31 KXS12048.1 - 2.4e-24 85.9 15.8 3.9e-24 85.2 15.8 1.3 1 0 0 1 1 1 1 Ion transport protein RmlD_sub_bind PF04321.17 KXS12048.1 - 0.095 11.8 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain RRM_1 PF00076.22 KXS12049.1 - 5.4e-08 32.6 0.0 0.00051 19.8 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MAPKK1_Int PF08923.10 KXS12049.1 - 0.16 11.8 0.3 0.99 9.2 0.0 2.1 2 0 0 2 2 2 0 Mitogen-activated protein kinase kinase 1 interacting PNRC PF15365.6 KXS12049.1 - 5.7 6.9 10.6 0.28 11.1 3.7 2.5 2 0 0 2 2 2 0 Proline-rich nuclear receptor coactivator motif Kinesin PF00225.23 KXS12050.1 - 7.6e-92 307.8 0.0 9.6e-92 307.4 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KXS12050.1 - 2.5e-23 82.7 0.0 4.6e-23 81.8 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding HHH_3 PF12836.7 KXS12050.1 - 4.5e-05 23.6 0.0 0.00011 22.3 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.6 KXS12050.1 - 0.044 14.4 0.2 0.16 12.6 0.2 2.0 2 0 0 2 2 2 0 Helix-hairpin-helix domain AphA_like PF14557.6 KXS12050.1 - 0.11 12.2 0.1 0.35 10.6 0.0 1.8 2 0 0 2 2 2 0 Putative AphA-like transcriptional regulator TPR_2 PF07719.17 KXS12051.1 - 6e-21 72.8 0.3 1.4e-05 24.9 0.1 6.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 KXS12051.1 - 4.9e-17 60.9 0.1 1.6e-05 24.5 0.1 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 KXS12051.1 - 7.8e-15 53.8 1.4 0.0023 18.0 0.1 6.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 KXS12051.1 - 3.5e-12 46.1 4.2 0.0025 18.5 0.0 6.7 4 1 2 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 KXS12051.1 - 2.2e-09 37.0 2.0 0.04 14.3 0.1 5.2 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 KXS12051.1 - 3.4e-09 36.1 0.9 0.015 15.3 0.0 6.9 6 1 0 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.6 KXS12051.1 - 3e-08 33.2 0.7 0.0068 16.1 0.0 5.4 4 1 2 6 6 6 2 TPR repeat TPR_16 PF13432.6 KXS12051.1 - 3.1e-08 34.1 4.3 0.002 18.7 0.0 5.6 6 1 1 7 7 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 KXS12051.1 - 4.6e-07 30.0 13.7 0.0068 16.7 0.1 5.8 5 1 2 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 KXS12051.1 - 1.7e-06 28.4 2.3 0.0037 17.7 0.1 4.5 3 1 3 6 6 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 KXS12051.1 - 1e-05 25.2 5.9 0.013 15.3 0.1 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_15 PF13429.6 KXS12051.1 - 0.00013 21.3 0.9 0.00013 21.3 0.9 3.6 5 1 0 5 5 5 1 Tetratricopeptide repeat NARP1 PF12569.8 KXS12051.1 - 0.00061 18.8 0.6 0.64 8.9 0.1 2.2 2 0 0 2 2 2 2 NMDA receptor-regulated protein 1 TPR_6 PF13174.6 KXS12051.1 - 0.0008 19.9 7.4 8.9 7.2 0.0 7.0 8 1 1 9 9 7 1 Tetratricopeptide repeat TPR_9 PF13371.6 KXS12051.1 - 0.0014 18.7 0.0 1 9.5 0.0 3.4 1 1 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KXS12051.1 - 0.0059 16.8 3.3 0.051 13.8 0.3 3.2 3 1 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.6 KXS12051.1 - 0.027 14.5 0.6 0.85 9.7 0.1 3.3 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat RPN7 PF10602.9 KXS12051.1 - 0.085 12.6 0.7 17 5.1 0.0 4.0 3 1 0 3 3 3 0 26S proteasome subunit RPN7 Sec63 PF02889.16 KXS12052.1 - 1.4e-141 470.0 0.0 5.9e-79 264.9 0.0 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 KXS12052.1 - 4.5e-48 163.3 0.0 2.9e-24 85.8 0.2 3.0 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.15 KXS12052.1 - 2.5e-23 82.9 0.0 1.8e-11 44.3 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KXS12052.1 - 5.6e-16 58.9 0.0 2.6e-06 27.8 0.0 3.7 2 1 0 2 2 2 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 KXS12052.1 - 5.5e-07 29.9 0.4 0.04 14.2 0.2 3.7 2 2 0 2 2 2 2 AAA domain PhoH PF02562.16 KXS12052.1 - 0.0075 15.7 0.0 2.1 7.8 0.0 2.7 2 0 0 2 2 2 2 PhoH-like protein IstB_IS21 PF01695.17 KXS12052.1 - 0.0089 15.8 0.3 0.58 9.9 0.0 3.4 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA_11 PF13086.6 KXS12052.1 - 0.087 12.6 0.1 2.7 7.7 0.0 2.9 3 1 1 4 4 4 0 AAA domain LCM PF04072.14 KXS12054.1 - 3.9e-28 98.7 0.0 1.5e-27 96.8 0.0 1.9 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase PfkB PF00294.24 KXS12054.1 - 0.12 11.6 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 pfkB family carbohydrate kinase Cyclin PF08613.11 KXS12055.1 - 6.5e-38 130.6 0.5 1.1e-37 130.0 0.5 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 KXS12055.1 - 0.035 13.9 0.1 0.058 13.1 0.1 1.3 1 0 0 1 1 1 0 Cyclin, N-terminal domain LRR_6 PF13516.6 KXS12056.1 - 1.2e-17 62.3 2.2 0.0011 18.9 0.0 5.9 5 0 0 5 5 5 4 Leucine Rich repeat LRR_1 PF00560.33 KXS12056.1 - 0.002 18.4 2.6 20 6.3 0.0 5.3 4 1 0 4 4 4 0 Leucine Rich Repeat CHASE8 PF17152.4 KXS12056.1 - 0.012 15.8 1.4 0.8 10.0 0.3 2.8 2 0 0 2 2 2 0 Periplasmic sensor domain MetOD2 PF18548.1 KXS12056.1 - 0.033 14.3 0.7 0.033 14.3 0.7 5.5 3 2 2 6 6 6 0 Metanogen output domain 2 Hema_stalk PF08720.10 KXS12056.1 - 0.05 13.3 0.3 0.16 11.7 0.3 1.8 1 0 0 1 1 1 0 Influenza C hemagglutinin stalk DUF3181 PF11378.8 KXS12056.1 - 0.068 13.5 0.1 1.8 8.9 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3181) LRR_8 PF13855.6 KXS12056.1 - 0.15 11.9 2.8 2.9 7.7 0.3 3.7 3 1 1 4 4 4 0 Leucine rich repeat LRR_4 PF12799.7 KXS12056.1 - 0.19 12.2 2.7 0.73 10.4 0.1 3.2 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) CALCOCO1 PF07888.11 KXS12056.1 - 0.96 8.2 64.9 0.29 10.0 10.3 3.1 1 1 2 3 3 3 0 Calcium binding and coiled-coil domain (CALCOCO1) like Baculo_PEP_C PF04513.12 KXS12056.1 - 1 9.4 16.0 0.36 10.9 2.9 3.9 1 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fez1 PF06818.15 KXS12056.1 - 6.4 7.2 56.8 6.8 7.1 6.1 3.2 1 1 1 3 3 3 0 Fez1 Tcp11 PF05794.13 KXS12057.1 - 3.3e-90 303.3 4.3 6.1e-90 302.4 4.3 1.4 1 0 0 1 1 1 1 T-complex protein 11 Atx10homo_assoc PF09759.9 KXS12059.1 - 1.5e-33 114.7 0.6 2.5e-33 114.0 0.6 1.3 1 0 0 1 1 1 1 Spinocerebellar ataxia type 10 protein domain DEAD PF00270.29 KXS12060.1 - 4.1e-44 150.4 0.0 6.9e-44 149.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXS12060.1 - 3.3e-28 98.2 0.1 9.1e-28 96.8 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXS12060.1 - 0.007 16.4 0.0 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KXS12060.1 - 0.15 12.4 0.1 0.9 9.8 0.1 2.2 1 1 0 1 1 1 0 AAA domain TFIIF_alpha PF05793.12 KXS12060.1 - 0.25 9.9 7.5 0.36 9.4 7.5 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Lin-8 PF03353.15 KXS12060.1 - 0.8 9.2 2.8 1.1 8.8 2.8 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist zf-C2H2_aberr PF17017.5 KXS12061.1 - 0.012 15.8 0.0 0.017 15.3 0.0 1.2 1 0 0 1 1 1 0 Aberrant zinc-finger WD40 PF00400.32 KXS12063.1 - 0.0009 20.0 2.5 0.019 15.8 0.1 3.2 3 0 0 3 3 3 1 WD domain, G-beta repeat DLIC PF05783.11 KXS12064.1 - 3.5e-75 253.6 0.0 1e-28 100.5 0.0 3.5 3 1 0 3 3 3 3 Dynein light intermediate chain (DLIC) AAA_16 PF13191.6 KXS12064.1 - 0.02 15.3 0.1 0.097 13.0 0.0 2.2 3 0 0 3 3 3 0 AAA ATPase domain GTP_EFTU PF00009.27 KXS12064.1 - 0.026 14.1 0.0 2.3 7.7 0.0 2.1 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain FtsK_SpoIIIE PF01580.18 KXS12064.1 - 0.027 13.8 0.0 0.05 12.9 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family G-alpha PF00503.20 KXS12064.1 - 0.11 11.6 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit AAA_29 PF13555.6 KXS12064.1 - 0.11 12.2 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain HbrB PF08539.11 KXS12065.1 - 4e-25 88.7 0.9 6.5e-18 65.3 0.0 2.3 1 1 1 2 2 2 2 HbrB-like eIF3g PF12353.8 KXS12066.1 - 4.1e-35 120.9 0.9 8.2e-35 119.9 0.9 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.22 KXS12066.1 - 3.7e-20 71.5 0.1 7e-20 70.6 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CDV3 PF15359.6 KXS12066.1 - 0.01 16.3 0.7 0.025 15.1 0.4 1.9 1 1 1 2 2 2 0 Carnitine deficiency-associated protein 3 DUF2576 PF10845.8 KXS12067.1 - 0.031 13.9 0.2 0.067 12.8 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2576) ABC_tran PF00005.27 KXS12068.1 - 2.9e-30 105.6 0.0 4.6e-30 104.9 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 KXS12068.1 - 6.2e-20 71.6 22.8 8.4e-20 71.2 22.8 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 KXS12068.1 - 2e-15 57.4 0.3 1.6e-09 38.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KXS12068.1 - 3.9e-05 23.2 0.1 0.0056 16.1 0.0 2.2 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain Mg_chelatase PF01078.21 KXS12068.1 - 0.0064 15.9 0.0 0.015 14.7 0.0 1.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_23 PF13476.6 KXS12068.1 - 0.012 16.1 0.2 0.022 15.3 0.2 1.3 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KXS12068.1 - 0.025 14.3 0.1 0.052 13.3 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain MPS-4 PF17523.2 KXS12068.1 - 0.045 13.9 0.7 0.045 13.9 0.7 2.4 2 0 0 2 2 2 0 MinK-related peptide, potassium channel accessory sub-unit protein 4 AAA_30 PF13604.6 KXS12068.1 - 0.05 13.3 0.1 0.2 11.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 KXS12068.1 - 0.054 13.2 0.0 5 6.7 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain SbcCD_C PF13558.6 KXS12068.1 - 0.07 13.4 0.0 1.1 9.6 0.0 2.6 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit ABC2_membrane_2 PF12679.7 KXS12068.1 - 1.4 8.1 15.1 2.8 7.1 15.1 1.5 1 1 0 1 1 1 0 ABC-2 family transporter protein RT_RNaseH_2 PF17919.1 KXS12069.1 - 1.4e-11 44.3 0.0 4.4e-11 42.7 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KXS12069.1 - 5.8e-11 42.6 0.0 1.2e-10 41.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase IML1 PF12257.8 KXS12070.1 - 4.7e-102 341.0 0.0 7.2e-102 340.3 0.0 1.3 1 0 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 DEP PF00610.21 KXS12070.1 - 3.2e-20 72.0 0.2 6.2e-20 71.0 0.2 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) IKI3 PF04762.12 KXS12071.1 - 1.1e-85 288.5 3.3 1.5e-72 245.0 0.5 2.3 3 0 0 3 3 3 2 IKI3 family DUF1878 PF08963.10 KXS12071.1 - 0.073 13.6 1.7 2.6 8.6 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1878) TCTP PF00838.17 KXS12073.1 - 3e-66 222.8 0.7 3.4e-66 222.7 0.7 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein PseudoU_synth_2 PF00849.22 KXS12074.1 - 5.7e-14 52.5 0.0 7.3e-14 52.2 0.0 1.2 1 0 0 1 1 1 1 RNA pseudouridylate synthase Sec39 PF08314.11 KXS12075.1 - 2.4e-23 82.6 13.9 3.6e-17 62.1 2.6 2.8 3 0 0 3 3 3 2 Secretory pathway protein Sec39 Nbas_N PF15492.6 KXS12075.1 - 2.6e-09 36.8 0.9 1.1e-07 31.4 0.3 3.1 2 1 0 2 2 2 1 Neuroblastoma-amplified sequence, N terminal ANAPC4_WD40 PF12894.7 KXS12075.1 - 0.00049 20.3 1.0 0.097 13.0 0.1 3.5 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain DUF4871 PF16167.5 KXS12075.1 - 0.1 12.6 0.6 0.94 9.5 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4871) RRN3 PF05327.11 KXS12076.1 - 8.9e-119 397.6 0.1 1.2e-118 397.1 0.1 1.0 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 ATP-synt_F PF01990.17 KXS12077.1 - 3.1e-33 113.9 0.3 3.5e-33 113.8 0.3 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit CorC_HlyC PF03471.17 KXS12077.1 - 0.0056 16.7 0.1 1.3 9.1 0.0 2.3 1 1 1 2 2 2 2 Transporter associated domain PIN_8 PF18476.1 KXS12077.1 - 0.044 13.6 0.0 0.049 13.5 0.0 1.1 1 0 0 1 1 1 0 PIN like domain Dynamin_N PF00350.23 KXS12078.1 - 1.1e-43 149.2 0.0 1.1e-43 149.2 0.0 2.7 3 0 0 3 3 3 1 Dynamin family Dynamin_M PF01031.20 KXS12078.1 - 6.4e-08 32.1 0.2 0.019 14.2 0.0 3.7 4 0 0 4 4 4 2 Dynamin central region MMR_HSR1 PF01926.23 KXS12078.1 - 8.3e-07 29.1 0.0 8.8e-06 25.8 0.0 2.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_21 PF13304.6 KXS12078.1 - 0.028 14.2 0.7 0.22 11.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system BAF1_ABF1 PF04684.13 KXS12078.1 - 0.061 12.4 13.5 0.15 11.1 13.5 1.5 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor AAA_15 PF13175.6 KXS12078.1 - 0.39 10.4 0.0 0.39 10.4 0.0 2.4 3 0 0 3 3 3 0 AAA ATPase domain AAA_23 PF13476.6 KXS12078.1 - 3.1 8.2 22.6 21 5.5 1.5 4.3 4 0 0 4 4 4 0 AAA domain UBA_4 PF14555.6 KXS12079.1 - 1.5e-14 53.5 0.1 2.2e-14 53.0 0.1 1.2 1 0 0 1 1 1 1 UBA-like domain TAP_C PF03943.13 KXS12079.1 - 0.04 13.5 0.0 0.06 13.0 0.0 1.2 1 0 0 1 1 1 0 TAP C-terminal domain RRM_1 PF00076.22 KXS12080.1 - 4.6e-55 183.3 0.0 1.2e-17 63.5 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KXS12080.1 - 1.5e-09 37.7 0.1 0.00013 21.9 0.0 3.3 3 0 0 3 3 3 3 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 KXS12080.1 - 2.3e-07 30.6 0.0 0.0017 18.2 0.0 2.9 3 1 0 3 3 3 2 Occluded RNA-recognition motif RRM_7 PF16367.5 KXS12080.1 - 3.8e-05 23.7 0.1 0.22 11.7 0.0 3.6 3 0 0 3 3 3 1 RNA recognition motif SET_assoc PF11767.8 KXS12080.1 - 7.5e-05 22.3 0.0 0.31 10.7 0.0 2.7 3 0 0 3 3 3 2 Histone lysine methyltransferase SET associated RRM_8 PF11835.8 KXS12080.1 - 0.00039 20.6 0.0 0.075 13.3 0.0 3.0 3 0 0 3 3 3 1 RRM-like domain RRM_5 PF13893.6 KXS12080.1 - 0.0021 17.6 0.0 0.019 14.6 0.0 2.2 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ank_4 PF13637.6 KXS12081.1 - 8.2e-21 74.1 0.7 0.00045 20.7 0.0 4.1 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXS12081.1 - 2.2e-16 60.2 0.2 1.4e-08 35.1 0.0 3.1 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 KXS12081.1 - 1.8e-14 53.5 3.7 0.00078 19.8 0.0 5.4 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 KXS12081.1 - 2e-12 46.1 1.0 0.0051 17.2 0.0 5.7 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 KXS12081.1 - 5.6e-11 42.5 3.5 0.0037 17.6 0.0 4.6 2 2 3 5 5 5 2 Ankyrin repeats (many copies) UCR_hinge PF02320.16 KXS12083.1 - 1.3e-19 70.2 6.0 1.5e-19 69.9 6.0 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein Ndufs5 PF10200.9 KXS12083.1 - 0.011 15.9 3.5 0.013 15.7 3.5 1.1 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa Ribosomal_S7 PF00177.21 KXS12085.1 - 9.4e-37 125.9 0.6 1.2e-36 125.6 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Sugar_tr PF00083.24 KXS12087.1 - 2.4e-35 122.3 26.3 7.4e-32 110.8 26.3 2.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXS12087.1 - 9.7e-33 113.5 36.7 3.2e-24 85.5 15.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KXS12087.1 - 1.1e-07 31.6 3.3 1.9e-07 30.7 3.3 1.4 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB MFS_1_like PF12832.7 KXS12087.1 - 0.00035 19.6 14.7 0.00085 18.3 10.2 2.6 1 1 1 2 2 2 2 MFS_1 like family MarR_2 PF12802.7 KXS12087.1 - 0.048 13.5 0.0 3.7 7.5 0.0 2.7 3 0 0 3 3 3 0 MarR family RNA_pol_Rpb8 PF03870.15 KXS12092.1 - 7.7e-40 136.3 0.0 8.6e-40 136.1 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 RNA_pol_RpbG PF16992.5 KXS12092.1 - 0.041 13.9 0.0 1.9 8.6 0.0 2.1 2 0 0 2 2 2 0 DNA-directed RNA polymerase, subunit G Guanylate_kin PF00625.21 KXS12093.1 - 1.1e-56 191.4 0.0 1.3e-56 191.2 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_16 PF13191.6 KXS12093.1 - 7.1e-08 33.0 0.0 1.2e-07 32.3 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KXS12093.1 - 0.00011 22.5 0.0 0.00022 21.5 0.0 1.6 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 KXS12093.1 - 0.00018 22.0 0.0 0.00019 21.9 0.0 1.4 1 1 0 1 1 1 1 ABC transporter Rad17 PF03215.15 KXS12093.1 - 0.00049 20.1 0.0 0.00063 19.7 0.0 1.2 1 0 0 1 1 1 1 Rad17 P-loop domain MMR_HSR1 PF01926.23 KXS12093.1 - 0.0037 17.3 0.0 0.0075 16.3 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_18 PF13238.6 KXS12093.1 - 0.0044 17.6 0.1 0.029 14.9 0.1 2.3 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 KXS12093.1 - 0.005 17.0 0.2 0.14 12.4 0.2 2.3 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 KXS12093.1 - 0.0064 16.4 0.0 0.01 15.8 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_28 PF13521.6 KXS12093.1 - 0.0066 16.7 0.0 0.05 13.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KXS12093.1 - 0.0082 16.1 0.0 0.068 13.2 0.0 2.4 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 KXS12093.1 - 0.0082 16.5 0.0 0.013 15.9 0.0 1.3 1 0 0 1 1 1 1 RNA helicase AAA_14 PF13173.6 KXS12093.1 - 0.014 15.4 0.0 0.022 14.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 KXS12093.1 - 0.016 15.1 0.0 0.028 14.3 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_29 PF13555.6 KXS12093.1 - 0.021 14.5 0.0 0.042 13.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.29 KXS12093.1 - 0.028 14.9 0.0 0.048 14.1 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) dNK PF01712.19 KXS12093.1 - 0.052 13.4 0.0 0.45 10.3 0.0 2.0 2 0 0 2 2 2 0 Deoxynucleoside kinase NACHT PF05729.12 KXS12093.1 - 0.11 12.4 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_7 PF12775.7 KXS12093.1 - 0.13 11.7 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_21 PF13304.6 KXS12093.1 - 0.19 11.5 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KXS12093.1 - 0.21 12.1 0.0 0.43 11.1 0.0 1.4 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.14 KXS12093.1 - 0.21 10.8 0.0 0.22 10.7 0.0 1.3 1 1 0 1 1 1 0 KAP family P-loop domain Sel1 PF08238.12 KXS12094.1 - 3.9e-32 110.0 14.5 5.7e-11 42.7 0.3 4.5 5 0 0 5 5 4 4 Sel1 repeat TPR_16 PF13432.6 KXS12094.1 - 7e-07 29.8 0.7 0.02 15.5 0.1 3.0 1 1 2 3 3 3 3 Tetratricopeptide repeat NHR2 PF08788.11 KXS12094.1 - 8.7e-06 25.4 0.7 0.18 11.6 0.0 3.9 4 0 0 4 4 4 2 NHR2 domain like TPR_12 PF13424.6 KXS12094.1 - 0.00026 21.2 1.7 0.9 9.9 0.0 4.0 4 2 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 KXS12094.1 - 0.0018 18.3 11.4 2.2 8.6 0.0 5.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 KXS12094.1 - 0.0026 17.8 9.2 2.4 8.6 0.0 5.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 KXS12094.1 - 0.0027 17.4 6.1 0.37 10.5 0.8 3.9 3 2 0 3 3 3 1 TPR repeat SPO22 PF08631.10 KXS12094.1 - 0.0038 16.7 3.4 0.89 9.0 0.0 3.7 1 1 1 3 3 3 1 Meiosis protein SPO22/ZIP4 like ANTAR PF03861.14 KXS12094.1 - 0.019 14.8 0.0 1.2 9.0 0.0 3.2 4 0 0 4 4 4 0 ANTAR domain TPR_14 PF13428.6 KXS12094.1 - 0.023 15.5 2.6 16 6.7 0.0 3.6 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 KXS12094.1 - 0.072 13.0 6.2 12 5.9 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 KXS12094.1 - 0.089 12.7 6.9 13 5.8 0.0 5.0 6 0 0 6 6 6 0 Tetratricopeptide repeat SpoIIAA-like PF11964.8 KXS12094.1 - 0.22 12.6 2.4 9.6 7.3 0.2 2.4 2 1 0 2 2 2 0 SpoIIAA-like TPR_5 PF12688.7 KXS12094.1 - 0.3 11.3 1.1 17 5.7 0.0 3.1 3 1 0 3 3 3 0 Tetratrico peptide repeat Enolase_like_N PF18374.1 KXS12094.1 - 0.46 9.9 4.9 11 5.5 0.1 3.6 4 0 0 4 4 4 0 Enolase N-terminal domain-like TPR_19 PF14559.6 KXS12094.1 - 0.75 10.3 4.0 11 6.6 0.1 2.8 2 2 0 2 2 2 0 Tetratricopeptide repeat MBG_2 PF18676.1 KXS12096.1 - 0.0075 16.9 0.5 0.0075 16.9 0.5 2.5 2 1 1 3 3 3 1 MBG domain (YGX type) Polysacc_deac_1 PF01522.21 KXS12096.1 - 0.043 13.7 0.0 0.12 12.3 0.0 1.7 2 0 0 2 2 2 0 Polysaccharide deacetylase CMD PF02627.20 KXS12097.1 - 0.00017 21.5 0.0 0.00035 20.5 0.0 1.5 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family Aldo_ket_red PF00248.21 KXS12099.1 - 1.4e-69 234.6 0.0 1.6e-69 234.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF4879 PF16219.5 KXS12099.1 - 0.12 12.5 0.1 1.9 8.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4879) DEAD PF00270.29 KXS12100.1 - 5.2e-43 146.8 0.0 8.9e-43 146.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXS12100.1 - 2.3e-22 79.4 0.1 5.4e-22 78.2 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF2306 PF10067.9 KXS12100.1 - 5.6e-06 26.6 3.6 9.4e-06 25.9 3.6 1.4 1 0 0 1 1 1 1 Predicted membrane protein (DUF2306) ResIII PF04851.15 KXS12100.1 - 0.0029 17.6 0.0 0.0052 16.8 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit F-box-like PF12937.7 KXS12101.1 - 5.8e-05 22.9 0.1 0.00011 22.0 0.1 1.5 1 0 0 1 1 1 1 F-box-like Pentapeptide_3 PF13576.6 KXS12101.1 - 0.082 13.1 0.2 5.3 7.3 0.1 2.5 2 0 0 2 2 2 0 Pentapeptide repeats (9 copies) Arm PF00514.23 KXS12102.1 - 4.4e-41 137.7 31.6 9.3e-12 44.6 0.3 9.4 10 0 0 10 10 10 6 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KXS12102.1 - 2.4e-12 47.1 25.0 3.6e-05 24.1 0.4 7.7 6 2 2 8 8 8 4 HEAT-like repeat HEAT_2 PF13646.6 KXS12102.1 - 4e-10 39.9 16.0 0.0053 17.1 0.4 6.2 3 2 3 6 6 6 4 HEAT repeats HEAT PF02985.22 KXS12102.1 - 6.3e-09 35.3 13.6 0.25 11.7 0.1 7.2 7 0 0 7 7 7 3 HEAT repeat Adaptin_N PF01602.20 KXS12102.1 - 2.1e-07 29.9 3.1 0.00033 19.3 0.3 2.3 1 1 1 2 2 2 2 Adaptin N terminal region V-ATPase_H_N PF03224.14 KXS12102.1 - 4.2e-05 23.0 0.0 0.00019 20.9 0.0 1.9 1 1 0 1 1 1 1 V-ATPase subunit H Arm_2 PF04826.13 KXS12102.1 - 0.00023 20.7 0.4 0.0012 18.4 0.2 2.1 1 1 1 2 2 2 1 Armadillo-like KAP PF05804.12 KXS12102.1 - 0.0044 15.2 0.0 0.15 10.2 0.0 2.4 1 1 1 2 2 2 1 Kinesin-associated protein (KAP) DUF3361 PF11841.8 KXS12102.1 - 0.0081 16.1 0.3 0.098 12.6 0.1 2.3 1 1 1 2 2 2 1 Domain of unknown function (DUF3361) Cnd1 PF12717.7 KXS12102.1 - 0.011 15.8 0.3 0.062 13.3 0.2 2.2 1 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 DUF5578 PF17741.1 KXS12102.1 - 0.017 14.6 0.9 3.9 6.8 0.0 3.0 2 1 1 3 3 3 0 Family of unknown function (DUF5578) V-ATPase_H_C PF11698.8 KXS12102.1 - 0.041 14.0 0.1 0.34 11.0 0.0 2.6 4 0 0 4 4 4 0 V-ATPase subunit H F-box PF00646.33 KXS12103.1 - 0.001 18.9 0.3 0.0019 18.0 0.3 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KXS12103.1 - 0.081 12.8 0.4 0.11 12.4 0.4 1.2 1 0 0 1 1 1 0 F-box-like adh_short PF00106.25 KXS12105.1 - 1.6e-12 47.3 0.0 2.3e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXS12105.1 - 3.9e-09 36.4 0.0 4.6e-09 36.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NmrA PF05368.13 KXS12105.1 - 0.0068 16.0 0.1 0.013 15.1 0.1 1.5 1 0 0 1 1 1 1 NmrA-like family F-box-like PF12937.7 KXS12106.1 - 1.5e-09 37.6 0.8 2.3e-09 37.0 0.3 1.6 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KXS12106.1 - 0.0012 18.6 0.0 0.0031 17.4 0.0 1.6 1 0 0 1 1 1 1 F-box domain HD PF01966.22 KXS12108.1 - 1.8e-06 28.2 0.0 3e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 HD domain DIOX_N PF14226.6 KXS12109.1 - 2.9e-21 76.4 0.0 4.4e-21 75.8 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KXS12109.1 - 3.2e-11 43.6 0.0 5.5e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DnaJ PF00226.31 KXS12110.1 - 4.9e-23 81.0 4.0 1.4e-22 79.6 4.0 1.8 1 0 0 1 1 1 1 DnaJ domain TPR_1 PF00515.28 KXS12110.1 - 6.9e-17 60.5 9.4 8.3e-06 25.4 0.1 6.6 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.17 KXS12110.1 - 2.3e-16 58.5 15.1 0.0032 17.5 0.1 6.7 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_9 PF13371.6 KXS12110.1 - 2.3e-12 46.8 27.4 2.7e-05 24.2 3.5 5.3 3 2 2 5 5 5 5 Tetratricopeptide repeat TPR_19 PF14559.6 KXS12110.1 - 1.5e-10 41.4 31.1 2.3e-05 24.8 2.1 5.8 2 2 2 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 KXS12110.1 - 1.8e-09 37.0 3.4 0.11 12.8 0.0 6.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 KXS12110.1 - 5.6e-08 33.0 37.0 0.012 16.4 0.2 8.2 4 3 4 8 8 7 5 Tetratricopeptide repeat TPR_16 PF13432.6 KXS12110.1 - 5.7e-07 30.1 44.7 0.00015 22.3 8.6 6.4 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 KXS12110.1 - 1.1e-05 25.0 15.5 0.019 14.6 6.5 5.0 4 1 1 5 5 5 3 TPR repeat ANAPC3 PF12895.7 KXS12110.1 - 0.00018 21.7 3.4 0.65 10.3 0.0 4.3 3 2 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 KXS12110.1 - 0.0018 18.5 16.8 0.14 12.5 1.5 5.9 3 3 2 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 KXS12110.1 - 0.0088 16.4 11.4 3.6 8.2 0.0 5.5 7 0 0 7 7 4 1 Tetratricopeptide repeat TPR_20 PF14561.6 KXS12110.1 - 0.0092 16.3 0.5 0.0092 16.3 0.5 5.1 5 1 2 7 7 6 1 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 KXS12110.1 - 0.022 14.4 1.2 0.42 10.3 0.2 2.6 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) DUF5545 PF17699.1 KXS12110.1 - 0.11 12.3 1.0 0.23 11.2 0.2 2.0 2 1 0 2 2 2 0 Family of unknown function (DUF5545) Alkyl_sulf_dimr PF14863.6 KXS12110.1 - 1 9.8 8.6 0.6 10.6 0.6 3.5 3 2 1 4 4 4 0 Alkyl sulfatase dimerisation TPR_7 PF13176.6 KXS12110.1 - 1.2 9.4 8.3 22 5.4 0.0 5.1 5 1 1 6 6 6 0 Tetratricopeptide repeat BTAD PF03704.17 KXS12110.1 - 5.3 7.5 15.5 0.6 10.5 1.0 3.6 3 1 0 3 3 3 0 Bacterial transcriptional activator domain TPR_6 PF13174.6 KXS12110.1 - 7.3 7.5 17.3 66 4.5 0.1 6.9 7 0 0 7 7 6 0 Tetratricopeptide repeat MIT PF04212.18 KXS12110.1 - 7.8 6.6 14.7 0.36 10.9 5.1 3.4 4 0 0 4 4 3 0 MIT (microtubule interacting and transport) domain 7tm_1 PF00001.21 KXS12111.1 - 1.5e-10 40.9 4.7 2.1e-10 40.4 4.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF3270 PF11674.8 KXS12113.1 - 0.032 14.4 0.7 0.049 13.8 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3270) CIA30 PF08547.12 KXS12114.1 - 7.4e-39 133.3 0.0 1e-38 132.9 0.0 1.2 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) SGBP_B_XBD PF18329.1 KXS12114.1 - 0.0053 16.7 0.0 0.0082 16.1 0.0 1.4 1 0 0 1 1 1 1 Surface glycan-binding protein B xyloglucan binding domain Ank_2 PF12796.7 KXS12115.1 - 2.3e-35 121.0 5.8 9.6e-09 35.7 0.1 6.3 2 2 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXS12115.1 - 5.2e-33 113.0 1.8 1.1e-05 25.8 0.0 8.8 4 3 4 9 9 9 6 Ankyrin repeats (many copies) Ank PF00023.30 KXS12115.1 - 6.7e-28 95.9 14.6 0.0015 18.9 0.0 9.1 9 0 0 9 9 9 7 Ankyrin repeat Ank_5 PF13857.6 KXS12115.1 - 1.2e-25 89.2 5.9 1.8e-05 24.9 0.0 6.5 5 2 1 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXS12115.1 - 9e-20 68.7 10.0 0.08 13.5 0.0 9.7 10 0 0 10 10 10 5 Ankyrin repeat HTH_46 PF15977.5 KXS12116.1 - 0.14 12.2 0.0 0.51 10.4 0.0 1.9 2 0 0 2 2 2 0 Winged helix-turn-helix DNA binding Aldo_ket_red PF00248.21 KXS12117.1 - 1.3e-33 116.5 0.0 1.5e-33 116.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family F-box-like PF12937.7 KXS12118.1 - 0.00092 19.1 0.4 0.0024 17.7 0.4 1.7 1 0 0 1 1 1 1 F-box-like Aldo_ket_red PF00248.21 KXS12119.1 - 6.9e-12 45.2 0.0 9.1e-12 44.8 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Mito_carr PF00153.27 KXS12121.1 - 7.3e-60 198.9 0.1 7.4e-23 80.3 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KXS12121.1 - 0.001 18.3 0.8 0.43 9.7 0.0 3.6 3 1 1 4 4 4 2 Gammaproteobacterial serine protease zf-RING_11 PF17123.5 KXS12124.1 - 0.0044 16.7 0.3 0.012 15.3 0.3 1.8 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 KXS12124.1 - 0.0093 16.3 2.8 0.045 14.1 2.8 2.1 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KXS12124.1 - 0.099 12.5 2.2 0.41 10.5 0.1 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KXS12124.1 - 0.24 11.7 5.1 2.1 8.7 5.1 2.3 1 1 0 1 1 1 0 RING-H2 zinc finger domain ECH_1 PF00378.20 KXS12125.1 - 6.6e-26 91.1 0.0 1.9e-25 89.6 0.0 1.6 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXS12125.1 - 1.7e-14 54.1 0.0 2.1e-14 53.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase RTA1 PF04479.13 KXS12126.1 - 4.4e-37 127.7 10.1 2.4e-23 82.8 5.7 2.0 1 1 1 2 2 2 2 RTA1 like protein zf-RING_2 PF13639.6 KXS12127.1 - 4.5e-11 42.9 4.3 9.7e-11 41.8 4.3 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KXS12127.1 - 5.7e-09 36.1 2.6 1.1e-08 35.2 2.6 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 KXS12127.1 - 3.7e-08 33.0 0.8 1.1e-07 31.5 0.8 1.8 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KXS12127.1 - 7.1e-08 32.2 3.0 7.1e-08 32.2 3.0 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXS12127.1 - 4.1e-06 26.7 1.3 1e-05 25.5 0.4 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KXS12127.1 - 7.9e-06 25.6 1.4 7.9e-06 25.6 1.4 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXS12127.1 - 1.3e-05 25.0 1.9 2.6e-05 24.1 1.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KXS12127.1 - 2.2e-05 24.3 1.9 4.3e-05 23.3 1.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KXS12127.1 - 0.00038 20.5 4.0 0.0023 18.0 4.0 2.1 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 KXS12127.1 - 0.022 14.6 2.4 0.052 13.4 2.4 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 FANCL_C PF11793.8 KXS12127.1 - 0.051 13.8 5.4 1.9 8.8 5.4 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain Thaumatin PF00314.17 KXS12129.1 - 4.7e-08 32.9 4.7 4.7e-08 32.9 4.7 5.7 3 2 2 5 5 5 2 Thaumatin family Carb_bind PF10645.9 KXS12129.1 - 9.3e-06 25.8 60.9 0.0012 19.0 3.8 5.8 6 0 0 6 6 6 4 Carbohydrate binding ACI44 PF15270.6 KXS12129.1 - 0.031 14.5 1.4 0.14 12.3 1.4 2.1 1 0 0 1 1 1 0 Metallo-carboxypeptidase inhibitor DSPc PF00782.20 KXS12130.1 - 9.3e-18 64.3 0.0 1.2e-17 63.9 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Rhodanese PF00581.20 KXS12130.1 - 0.015 15.8 0.0 0.34 11.5 0.0 2.9 3 1 0 3 3 3 0 Rhodanese-like domain DEK_C PF08766.11 KXS12131.1 - 0.12 12.3 0.1 0.19 11.7 0.1 1.2 1 0 0 1 1 1 0 DEK C terminal domain VHS PF00790.19 KXS12132.1 - 1.4e-39 135.2 0.2 2.3e-37 128.0 0.0 2.4 2 0 0 2 2 2 1 VHS domain FYVE PF01363.21 KXS12132.1 - 8e-18 64.3 7.8 1.3e-17 63.7 7.8 1.3 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.20 KXS12132.1 - 0.00022 20.9 15.1 0.0048 16.7 1.5 3.1 3 0 0 3 3 3 2 Ubiquitin interaction motif FYVE_2 PF02318.16 KXS12132.1 - 0.0087 16.3 6.2 0.01 16.0 4.7 1.8 2 0 0 2 2 2 1 FYVE-type zinc finger HypA PF01155.19 KXS12132.1 - 0.19 11.8 0.5 0.39 10.7 0.5 1.5 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 KXS12132.1 - 1.3 9.1 10.9 16 5.6 0.6 2.3 1 1 1 2 2 2 0 Double zinc ribbon DnaJ_CXXCXGXG PF00684.19 KXS12132.1 - 1.8 9.0 9.8 0.82 10.1 3.2 2.3 1 1 0 2 2 2 0 DnaJ central domain Cellulase PF00150.18 KXS12137.1 - 6.5e-19 68.4 0.5 1.9e-18 66.9 0.5 1.6 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Ank_2 PF12796.7 KXS12138.1 - 6.8e-17 61.8 0.6 6.8e-07 29.8 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXS12138.1 - 1.2e-08 35.1 6.0 0.069 13.5 0.0 5.5 4 2 2 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXS12138.1 - 1.2e-06 28.3 2.1 14 6.6 0.0 6.3 5 1 1 6 6 6 2 Ankyrin repeat Ank_4 PF13637.6 KXS12138.1 - 1.6e-06 28.5 2.3 0.87 10.2 0.0 4.9 3 2 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 KXS12138.1 - 1.3e-05 25.4 5.3 1.6 9.3 0.1 5.7 3 3 2 5 5 5 2 Ankyrin repeat HBS1_N PF08938.10 KXS12138.1 - 0.035 14.4 0.0 0.078 13.3 0.0 1.6 1 0 0 1 1 1 0 HBS1 N-terminus FUSC PF04632.12 KXS12139.1 - 1.8 7.0 8.9 2.5 6.5 8.9 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Ank_2 PF12796.7 KXS12140.1 - 5.3e-27 94.2 0.0 3.1e-12 46.9 0.0 2.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXS12140.1 - 2e-14 53.7 0.7 6.9e-06 26.5 0.0 4.3 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 KXS12140.1 - 1.2e-13 50.8 0.6 0.0011 19.3 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 KXS12140.1 - 1.2e-11 43.8 0.3 0.0022 18.3 0.0 4.4 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 KXS12140.1 - 2.5e-11 43.6 2.6 0.0074 16.6 0.1 4.3 2 1 2 4 4 4 3 Ankyrin repeats (many copies) SnoaL_2 PF12680.7 KXS12143.1 - 0.00039 21.0 0.0 0.00059 20.4 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 KXS12143.1 - 0.00098 19.5 0.1 0.002 18.5 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4440) LEH PF07858.12 KXS12143.1 - 0.0029 17.7 0.1 0.0045 17.1 0.1 1.3 1 1 0 1 1 1 1 Limonene-1,2-epoxide hydrolase catalytic domain Lumazine_bd_2 PF12893.7 KXS12143.1 - 0.09 13.5 0.0 0.62 10.7 0.0 2.0 2 1 0 2 2 2 0 Putative lumazine-binding F-box-like PF12937.7 KXS12144.1 - 0.00049 19.9 0.0 0.00097 19.0 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 KXS12144.1 - 0.0015 18.4 0.0 0.011 15.7 0.0 2.2 2 0 0 2 2 2 1 F-box F-box PF00646.33 KXS12144.1 - 0.0034 17.2 0.0 0.01 15.7 0.0 1.8 2 0 0 2 2 2 1 F-box domain FAD_binding_4 PF01565.23 KXS12145.1 - 1.6e-13 50.5 3.6 2.2e-08 33.9 2.6 2.5 2 0 0 2 2 2 2 FAD binding domain FAD_binding_4 PF01565.23 KXS12146.1 - 1.8e-27 95.8 2.6 3.6e-27 94.8 2.6 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXS12146.1 - 4.4e-13 49.1 0.5 9.3e-13 48.1 0.1 1.8 2 0 0 2 2 2 1 Berberine and berberine like Nitroreductase PF00881.24 KXS12147.1 - 2.7e-30 105.7 0.0 3.6e-30 105.2 0.0 1.2 1 0 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 KXS12147.1 - 4e-06 26.6 0.1 0.00059 19.5 0.1 2.7 2 1 0 2 2 2 2 Putative TM nitroreductase CTX_RstB PF07459.11 KXS12148.1 - 0.061 13.6 0.0 0.1 12.8 0.0 1.3 1 0 0 1 1 1 0 CTX phage RstB protein Pkinase PF00069.25 KXS12149.1 - 1.1e-25 90.5 0.0 3.5e-25 88.9 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS12149.1 - 7.7e-09 35.2 0.0 2.7e-06 26.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KXS12149.1 - 0.0002 21.4 0.1 0.00041 20.3 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KXS12149.1 - 0.16 11.2 0.0 0.29 10.4 0.0 1.3 1 0 0 1 1 1 0 Kinase-like RR_TM4-6 PF06459.12 KXS12149.1 - 0.37 10.6 15.5 0.69 9.7 15.5 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 F-box-like PF12937.7 KXS12150.1 - 2.8e-08 33.5 0.7 6e-08 32.5 0.7 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXS12150.1 - 0.00033 20.4 0.7 0.00072 19.4 0.7 1.5 1 0 0 1 1 1 1 F-box domain MFS_1 PF07690.16 KXS12151.1 - 2e-22 79.6 36.7 2.8e-22 79.1 36.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXS12151.1 - 7.4e-06 25.1 18.5 0.00038 19.4 1.6 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.6 KXS12151.1 - 0.00049 18.8 5.3 0.00049 18.8 5.3 2.1 2 1 0 2 2 2 1 MFS/sugar transport protein zf-LITAF-like PF10601.9 KXS12151.1 - 2.6 8.4 4.2 1.1 9.6 0.1 2.5 2 1 0 2 2 2 0 LITAF-like zinc ribbon domain HMG_box PF00505.19 KXS12154.1 - 3.9e-20 72.0 0.0 5.9e-20 71.5 0.0 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KXS12154.1 - 8.3e-07 29.5 0.0 1.6e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 HMG-box domain MATalpha_HMGbox PF04769.12 KXS12154.1 - 0.0044 16.4 0.0 0.0068 15.7 0.0 1.2 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 HMG-box RNA_pol_Rpc34 PF05158.12 KXS12157.1 - 2.8e-56 191.3 0.0 4e-56 190.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit Rrf2 PF02082.20 KXS12157.1 - 0.002 18.4 0.5 0.0048 17.2 0.2 1.8 2 0 0 2 2 2 1 Transcriptional regulator MarR_2 PF12802.7 KXS12157.1 - 0.0059 16.5 0.3 0.03 14.2 0.1 2.1 2 0 0 2 2 2 1 MarR family TrmB PF01978.19 KXS12157.1 - 0.011 15.6 0.1 0.16 11.9 0.2 2.2 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB Penicillinase_R PF03965.16 KXS12157.1 - 0.013 15.9 0.3 7.6 6.9 0.2 2.4 2 0 0 2 2 2 0 Penicillinase repressor GntR PF00392.21 KXS12157.1 - 0.017 14.7 0.3 0.34 10.6 0.1 2.2 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family HTH_36 PF13730.6 KXS12157.1 - 0.018 15.0 0.0 0.059 13.3 0.0 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_41 PF14502.6 KXS12157.1 - 0.019 14.7 0.1 0.033 13.9 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain PadR PF03551.14 KXS12157.1 - 0.025 14.5 0.8 11 6.1 0.0 2.8 3 0 0 3 3 3 0 Transcriptional regulator PadR-like family HTH_20 PF12840.7 KXS12157.1 - 0.046 13.8 0.2 0.27 11.3 0.0 2.3 3 0 0 3 3 3 0 Helix-turn-helix domain Replic_Relax PF13814.6 KXS12157.1 - 0.097 12.7 0.3 5.7 6.9 0.0 2.2 2 0 0 2 2 2 0 Replication-relaxation DUF3668 PF12416.8 KXS12158.1 - 2.3e-30 106.1 0.0 4.7e-30 105.1 0.0 1.5 1 0 0 1 1 1 1 Cep120 protein C2 PF00168.30 KXS12158.1 - 0.0016 18.7 0.0 0.11 12.8 0.0 3.1 3 0 0 3 3 3 1 C2 domain Ribosomal_S28e PF01200.18 KXS12159.1 - 2.2e-33 114.0 1.0 2.5e-33 113.9 1.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e Phostensin_N PF13916.6 KXS12159.1 - 0.076 13.4 0.0 0.079 13.3 0.0 1.1 1 0 0 1 1 1 0 PP1-regulatory protein, Phostensin N-terminal EMC3_TMCO1 PF01956.16 KXS12160.1 - 1e-56 191.3 2.8 1.3e-56 191.0 2.8 1.1 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like DUF2208 PF09973.9 KXS12160.1 - 0.011 15.3 0.2 0.011 15.3 0.2 1.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2208) WD40 PF00400.32 KXS12161.1 - 1.1e-24 86.2 24.5 1.9e-05 25.3 0.2 8.3 8 0 0 8 8 8 5 WD domain, G-beta repeat Bromodomain PF00439.25 KXS12161.1 - 1.4e-14 53.9 0.0 2.9e-14 52.9 0.0 1.5 1 0 0 1 1 1 1 Bromodomain ANAPC4_WD40 PF12894.7 KXS12161.1 - 1.3e-09 38.3 0.8 0.036 14.4 0.1 4.9 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KXS12161.1 - 0.0036 16.0 0.4 0.88 8.1 0.0 2.5 2 0 0 2 2 2 2 Nucleoporin Nup120/160 Pkinase PF00069.25 KXS12162.1 - 4e-76 255.9 0.0 5.2e-76 255.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS12162.1 - 5.1e-48 163.6 0.0 7.1e-48 163.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 KXS12162.1 - 1.5e-21 76.5 0.0 4.2e-21 75.1 0.0 1.9 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.6 KXS12162.1 - 1.3e-07 31.2 0.0 2.1e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KXS12162.1 - 4.2e-06 25.8 0.0 4.2e-06 25.8 0.0 2.4 3 0 0 3 3 3 1 Fungal protein kinase DSHCT PF08148.12 KXS12162.1 - 0.0038 16.9 0.0 0.0072 16.0 0.0 1.4 1 0 0 1 1 1 1 DSHCT (NUC185) domain Kdo PF06293.14 KXS12162.1 - 0.01 15.2 0.1 0.041 13.2 0.0 1.8 1 1 1 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXS12162.1 - 0.43 10.5 0.0 0.43 10.5 0.0 2.8 2 1 1 3 3 3 0 Phosphotransferase enzyme family DUF89 PF01937.19 KXS12163.1 - 6.9e-70 235.8 0.2 8.3e-70 235.5 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 Fumble PF03630.14 KXS12164.1 - 1.7e-132 441.6 0.0 2.8e-132 440.9 0.0 1.3 1 0 0 1 1 1 1 Fumble DUF89 PF01937.19 KXS12164.1 - 9.9e-40 136.6 0.1 1.5e-39 136.0 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF89 Spc7 PF08317.11 KXS12165.1 - 8.5e-14 51.1 10.0 1.3e-13 50.5 10.0 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF3767 PF12597.8 KXS12165.1 - 0.13 12.0 0.1 0.31 10.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3767) Pkinase PF00069.25 KXS12166.1 - 5.8e-51 173.4 0.2 7.1e-26 91.1 0.3 2.9 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXS12166.1 - 5.5e-22 78.3 0.1 5.6e-14 52.1 0.1 3.3 3 1 0 3 3 3 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXS12166.1 - 0.00052 18.9 0.0 0.00089 18.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 KXS12166.1 - 0.011 15.4 0.0 0.025 14.2 0.0 1.6 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KXS12166.1 - 0.021 14.7 0.0 0.8 9.6 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.6 KXS12166.1 - 0.099 11.9 0.0 5.3 6.3 0.0 2.2 2 0 0 2 2 2 0 Kinase-like HABP4_PAI-RBP1 PF04774.15 KXS12167.1 - 3.7e-10 40.7 10.0 3.7e-10 40.7 10.0 2.7 3 0 0 3 3 3 1 Hyaluronan / mRNA binding family Stm1_N PF09598.10 KXS12167.1 - 1.2e-05 26.0 6.8 1.2e-05 26.0 6.8 4.2 3 1 0 3 3 3 1 Stm1 HEAT_2 PF13646.6 KXS12168.1 - 1.4e-10 41.4 6.3 0.025 15.0 0.0 8.1 9 1 1 10 10 10 3 HEAT repeats HEAT PF02985.22 KXS12168.1 - 4.9e-09 35.7 15.1 0.46 10.9 0.0 9.8 9 0 0 9 9 9 3 HEAT repeat Arm PF00514.23 KXS12168.1 - 0.02 14.9 1.2 19 5.5 0.1 5.2 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat U3snoRNP10 PF12397.8 KXS12168.1 - 0.21 11.9 1.4 13 6.2 0.0 3.7 3 0 0 3 3 3 0 U3 small nucleolar RNA-associated protein 10 Nipped-B_C PF12830.7 KXS12168.1 - 0.25 11.3 2.9 4.7 7.1 0.0 4.3 5 1 0 5 5 5 0 Sister chromatid cohesion C-terminus HEAT_EZ PF13513.6 KXS12168.1 - 0.37 11.4 9.9 6.7 7.3 0.0 6.5 7 0 0 7 7 7 0 HEAT-like repeat Cnd1 PF12717.7 KXS12168.1 - 0.94 9.5 10.5 74 3.3 0.2 6.6 8 1 1 9 9 9 0 non-SMC mitotic condensation complex subunit 1 DUF3730 PF12530.8 KXS12168.1 - 8.9 5.8 7.9 3.1 7.3 0.1 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3730) ORC5_C PF14630.6 KXS12169.1 - 1.7e-55 188.6 0.0 2.4e-55 188.1 0.0 1.2 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.6 KXS12169.1 - 5.5e-13 49.7 0.0 6.3e-12 46.2 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KXS12169.1 - 2.4e-06 27.9 0.1 6e-05 23.3 0.1 2.6 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 KXS12169.1 - 0.015 15.2 0.1 0.16 11.9 0.0 2.2 2 0 0 2 2 2 0 NACHT domain ATPase_2 PF01637.18 KXS12169.1 - 0.019 14.9 0.0 0.098 12.6 0.0 2.0 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA PF00004.29 KXS12169.1 - 0.052 14.0 0.0 0.14 12.6 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KXS12169.1 - 0.073 12.8 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.6 KXS12169.1 - 0.08 12.7 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF815 PF05673.13 KXS12169.1 - 0.11 11.6 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) PIF1 PF05970.14 KXS12169.1 - 0.18 10.9 0.0 0.3 10.2 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase Ribosomal_L6 PF00347.23 KXS12171.1 - 5.4e-28 97.5 9.6 2.8e-14 53.5 1.6 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 Ribosomal_L19 PF01245.20 KXS12171.1 - 0.11 12.5 3.1 0.086 12.8 0.8 2.0 2 0 0 2 2 2 0 Ribosomal protein L19 zf-H2C2_2 PF13465.6 KXS12172.1 - 3.8e-10 39.7 2.5 0.00018 21.8 0.2 3.5 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 KXS12172.1 - 9.9e-10 38.3 7.1 6.1e-05 23.2 0.3 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXS12172.1 - 3.3e-07 30.6 5.8 0.0041 17.8 1.1 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KXS12172.1 - 0.00098 18.8 4.2 0.13 12.1 1.2 2.5 2 0 0 2 2 2 2 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 KXS12172.1 - 0.011 16.0 0.7 1.8 8.9 0.6 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KXS12172.1 - 0.23 11.5 2.0 13 5.9 0.2 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KXS12172.1 - 7.7 6.4 9.6 1.8 8.4 0.3 2.6 3 0 0 3 3 3 0 zinc-finger C2H2-type Pyr_redox_2 PF07992.14 KXS12174.1 - 2.9e-08 33.3 0.0 2.1e-05 23.9 0.0 3.3 2 2 2 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXS12174.1 - 1e-07 31.5 0.0 1.9e-06 27.4 0.0 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KXS12174.1 - 1.2e-06 27.3 0.0 6.6e-06 24.8 0.0 2.2 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KXS12174.1 - 1.3e-06 28.5 0.2 2.4e-05 24.5 0.1 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.20 KXS12174.1 - 0.00024 21.2 0.5 0.0096 16.0 0.0 2.5 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase ThiF PF00899.21 KXS12174.1 - 0.017 14.5 0.1 1.4 8.2 0.0 2.2 2 0 0 2 2 2 0 ThiF family Pyr_redox PF00070.27 KXS12174.1 - 0.028 15.0 1.0 2.4 8.8 0.5 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KXS12174.1 - 0.036 13.3 0.7 0.14 11.3 0.2 2.1 3 0 0 3 3 3 0 FAD binding domain 2-Hacid_dh_C PF02826.19 KXS12174.1 - 0.043 13.2 0.0 0.13 11.6 0.0 1.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Thi4 PF01946.17 KXS12174.1 - 0.17 11.1 0.1 5.4 6.2 0.0 2.3 2 0 0 2 2 2 0 Thi4 family DAO PF01266.24 KXS12174.1 - 0.19 11.3 3.0 28 4.1 0.1 3.7 3 1 1 4 4 4 0 FAD dependent oxidoreductase MOZ_SAS PF01853.18 KXS12175.1 - 1.9e-66 223.1 0.0 2.5e-66 222.7 0.0 1.1 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 KXS12175.1 - 8.2e-19 67.0 0.0 1.3e-18 66.3 0.0 1.4 1 0 0 1 1 1 1 MYST family zinc finger domain Tudor-knot PF11717.8 KXS12175.1 - 6.4e-12 45.2 0.0 1.5e-11 44.0 0.0 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 KXS12175.1 - 0.005 17.2 0.0 0.01 16.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain zf-C2H2_4 PF13894.6 KXS12175.1 - 0.16 12.9 0.6 0.52 11.3 0.6 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger Lectin_C PF00059.21 KXS12176.1 - 0.043 14.5 1.5 0.16 12.7 0.1 2.5 3 0 0 3 3 3 0 Lectin C-type domain SPX PF03105.19 KXS12176.1 - 0.12 12.2 4.0 0.18 11.7 4.0 1.2 1 0 0 1 1 1 0 SPX domain Apt1 PF10351.9 KXS12176.1 - 0.26 10.1 5.7 0.35 9.7 5.7 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SOG2 PF10428.9 KXS12176.1 - 0.72 9.0 19.9 1.2 8.2 19.9 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein Ammonium_transp PF00909.21 KXS12177.1 - 8.7e-94 314.4 30.7 9.9e-94 314.3 30.7 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family 2-Hacid_dh_C PF02826.19 KXS12178.1 - 2.5e-48 163.8 0.0 3.5e-48 163.3 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KXS12178.1 - 6.4e-22 77.7 0.0 7.5e-22 77.4 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KXS12178.1 - 0.043 14.0 0.0 0.1 12.7 0.0 1.6 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Rad21_Rec8_N PF04825.13 KXS12179.1 - 4.6e-22 78.3 0.0 8.2e-22 77.5 0.0 1.3 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 KXS12179.1 - 1.3e-07 30.8 0.4 2.8e-07 29.7 0.0 1.8 2 0 0 2 2 2 1 Conserved region of Rad21 / Rec8 like protein SMC_ScpA PF02616.14 KXS12179.1 - 0.013 15.4 0.0 0.019 14.9 0.0 1.2 1 0 0 1 1 1 0 Segregation and condensation protein ScpA Ank_2 PF12796.7 KXS12180.1 - 6.7e-35 119.5 13.5 3.9e-10 40.2 1.8 6.5 3 1 4 8 8 8 6 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXS12180.1 - 9.7e-25 83.9 17.8 0.0059 17.0 0.1 12.3 14 0 0 14 14 14 5 Ankyrin repeat Ank_4 PF13637.6 KXS12180.1 - 1.9e-24 85.7 18.0 0.00017 22.0 0.2 10.2 4 3 8 12 12 12 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXS12180.1 - 2.5e-18 65.9 15.1 5.9e-05 23.3 0.2 7.4 4 2 3 7 7 7 4 Ankyrin repeats (many copies) Ank PF00023.30 KXS12180.1 - 6e-18 64.4 23.2 0.0013 19.0 0.2 10.6 11 0 0 11 11 11 5 Ankyrin repeat DUF249 PF03158.13 KXS12180.1 - 0.013 15.2 0.0 0.89 9.2 0.0 3.2 3 1 0 3 3 3 0 Multigene family 530 protein SoPB_HTH PF18090.1 KXS12180.1 - 0.019 15.1 1.0 4 7.6 0.0 3.9 2 1 1 3 3 3 0 Centromere-binding protein HTH domain DUF2298 PF10060.9 KXS12180.1 - 0.058 12.1 6.0 0.095 11.4 0.6 2.5 2 1 1 3 3 3 0 Uncharacterized membrane protein (DUF2298) Oxidored_q6 PF01058.22 KXS12181.1 - 2.8e-23 82.2 0.2 3.9e-23 81.7 0.2 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit MMACHC PF16690.5 KXS12182.1 - 0.037 13.7 0.0 0.53 9.9 0.0 2.4 3 0 0 3 3 3 0 Methylmalonic aciduria and homocystinuria type C family ABC1 PF03109.16 KXS12183.1 - 3.7e-22 78.7 0.1 8.5e-15 55.0 0.1 2.5 2 0 0 2 2 2 2 ABC1 family RIO1 PF01163.22 KXS12183.1 - 3.6e-06 26.7 0.0 7.5e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 RIO1 family Pkinase PF00069.25 KXS12183.1 - 0.0031 16.9 0.1 0.0081 15.6 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain APH PF01636.23 KXS12183.1 - 0.014 15.3 0.0 0.049 13.6 0.0 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family WaaY PF06176.11 KXS12183.1 - 0.14 11.8 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) CHRD PF07452.12 KXS12184.1 - 6.1e-16 59.4 0.1 6.1e-16 59.4 0.1 2.6 2 1 0 2 2 2 1 CHRD domain DNA_pol_A_exo1 PF01612.20 KXS12185.1 - 3.3e-13 49.7 0.0 5.2e-13 49.1 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease Spo7 PF03907.13 KXS12188.1 - 1.1e-06 28.3 1.3 1.6e-06 27.8 1.3 1.4 1 1 0 1 1 1 1 Spo7-like protein NICE-1 PF15845.5 KXS12188.1 - 0.89 10.4 11.9 2.3 9.0 3.6 2.7 2 1 1 3 3 3 0 Cysteine-rich C-terminal 1 family Thiolase_N PF00108.23 KXS12189.1 - 9e-16 58.0 0.0 5.1e-12 45.7 0.0 2.3 1 1 1 2 2 2 2 Thiolase, N-terminal domain Thiolase_C PF02803.18 KXS12189.1 - 2.6e-08 33.5 0.1 1.5e-07 31.1 0.1 2.3 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KXS12189.1 - 7.9e-05 22.3 0.4 0.071 12.7 0.1 2.7 1 1 1 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KXS12189.1 - 0.012 15.5 1.1 0.94 9.4 0.1 2.8 2 1 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Amidohydro_1 PF01979.20 KXS12190.1 - 1.3e-51 176.0 0.0 1.9e-51 175.4 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KXS12190.1 - 2.4e-09 37.2 0.7 1e-06 28.5 0.1 2.2 2 0 0 2 2 2 2 Amidohydrolase family ECH_1 PF00378.20 KXS12192.1 - 1.4e-29 103.2 0.0 1.7e-29 102.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXS12192.1 - 3.9e-08 33.2 0.0 4.6e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase CRC_subunit PF08624.10 KXS12195.1 - 5.1e-34 117.6 0.0 8.1e-34 117.0 0.0 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit PHD PF00628.29 KXS12195.1 - 3.5e-21 74.8 36.4 1e-10 41.3 8.7 3.8 3 1 1 4 4 4 3 PHD-finger PHD_4 PF16866.5 KXS12195.1 - 0.0075 16.3 3.3 0.0075 16.3 3.3 3.7 2 1 1 3 3 3 1 PHD-finger C1_1 PF00130.22 KXS12195.1 - 0.013 15.4 31.5 0.061 13.2 7.0 4.1 3 1 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) SRP_SPB PF02978.19 KXS12195.1 - 0.2 12.3 0.4 0.46 11.1 0.4 1.5 1 0 0 1 1 1 0 Signal peptide binding domain AT_hook PF02178.19 KXS12195.1 - 7.1 6.9 34.6 0.43 10.6 3.7 3.8 3 0 0 3 3 3 0 AT hook motif EVE PF01878.18 KXS12196.1 - 9.6e-47 158.6 0.3 1.7e-46 157.8 0.0 1.6 2 0 0 2 2 2 1 EVE domain Vpu PF00558.19 KXS12196.1 - 1.2 8.9 2.6 25 4.7 0.3 2.2 2 0 0 2 2 2 0 Vpu protein Presenilin PF01080.17 KXS12196.1 - 6.3 5.4 4.5 1.3 7.7 0.3 1.7 2 0 0 2 2 2 0 Presenilin adh_short PF00106.25 KXS12197.1 - 1.3e-40 138.9 0.1 1.8e-40 138.5 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXS12197.1 - 1.6e-20 73.7 0.0 2.2e-20 73.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXS12197.1 - 4.9e-07 29.8 0.1 9.1e-07 29.0 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXS12197.1 - 0.0033 16.9 0.1 0.0072 15.8 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 KXS12197.1 - 0.0083 16.0 0.1 0.015 15.2 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KXS12197.1 - 0.033 14.2 0.1 0.17 11.9 0.0 2.0 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Glyco_tran_WecB PF03808.13 KXS12197.1 - 0.037 14.0 0.0 0.57 10.1 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family Sacchrp_dh_NADP PF03435.18 KXS12197.1 - 0.056 13.7 0.1 0.11 12.7 0.1 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain PqqD PF05402.12 KXS12197.1 - 0.091 13.1 0.1 0.2 12.0 0.1 1.6 1 0 0 1 1 1 0 Coenzyme PQQ synthesis protein D (PqqD) WD40 PF00400.32 KXS12198.1 - 1.4e-61 202.9 23.9 1.5e-11 44.6 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXS12198.1 - 2.2e-23 82.3 0.6 3.1e-05 24.2 0.0 6.0 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KXS12198.1 - 1e-11 45.1 0.0 1.2e-07 31.8 0.0 3.8 1 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KXS12198.1 - 1.5e-11 43.6 8.3 0.0017 17.1 0.1 5.3 3 1 3 6 6 6 3 Nucleoporin Nup120/160 WD40_like PF17005.5 KXS12198.1 - 6.2e-07 29.0 0.0 0.0004 19.8 0.0 3.5 2 1 2 4 4 4 2 WD40-like domain Ge1_WD40 PF16529.5 KXS12198.1 - 2.2e-06 26.9 1.4 0.28 10.1 0.6 3.7 1 1 2 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PALB2_WD40 PF16756.5 KXS12198.1 - 0.0026 16.7 2.4 8.3 5.2 0.0 4.0 1 1 3 4 4 4 2 Partner and localizer of BRCA2 WD40 domain DUF1513 PF07433.11 KXS12198.1 - 0.017 14.2 0.0 3.1 6.8 0.0 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF1513) VID27 PF08553.10 KXS12198.1 - 0.089 11.8 0.0 0.77 8.7 0.0 2.1 2 1 1 3 3 3 0 VID27 C-terminal WD40-like domain Cytochrom_D1 PF02239.16 KXS12198.1 - 0.09 11.3 0.0 4 5.9 0.0 2.6 2 1 1 3 3 3 0 Cytochrome D1 heme domain Nucleoporin_N PF08801.11 KXS12198.1 - 0.13 10.9 8.1 1.3 7.6 0.3 4.1 1 1 2 4 4 4 0 Nup133 N terminal like Pectinesterase PF01095.19 KXS12199.1 - 6.6e-20 71.0 0.6 5.5e-16 58.1 0.3 2.1 2 0 0 2 2 2 2 Pectinesterase LMBR1 PF04791.16 KXS12200.1 - 7.7e-106 355.0 0.0 1.7e-105 353.8 0.0 1.5 1 1 1 2 2 2 1 LMBR1-like membrane protein TFIIB PF00382.19 KXS12200.1 - 2e-15 56.6 1.5 1.6e-09 37.7 0.1 2.5 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 KXS12200.1 - 2.4e-06 27.0 1.4 4.6e-06 26.0 1.4 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding F-box-like PF12937.7 KXS12201.1 - 3.3e-10 39.7 0.2 1e-09 38.1 0.2 1.9 1 0 0 1 1 1 1 F-box-like F-box_5 PF18511.1 KXS12201.1 - 4.9e-07 29.2 1.4 2.2e-06 27.1 0.0 2.3 2 0 0 2 2 2 1 F-box F-box PF00646.33 KXS12201.1 - 0.00067 19.5 0.2 0.0082 16.0 0.0 2.7 2 0 0 2 2 2 1 F-box domain PRANC PF09372.10 KXS12201.1 - 0.19 12.1 0.0 0.35 11.2 0.0 1.4 1 0 0 1 1 1 0 PRANC domain DUF1388 PF07142.12 KXS12202.1 - 0.19 11.7 0.8 0.29 11.1 0.8 1.2 1 0 0 1 1 1 0 Repeat of unknown function (DUF1388) WD40 PF00400.32 KXS12203.1 - 1.7e-20 72.9 9.2 2.1e-05 25.2 0.3 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXS12203.1 - 4.3e-06 26.9 0.0 0.03 14.6 0.0 4.1 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 KXS12203.1 - 0.0032 17.9 0.1 0.2 12.2 0.1 3.3 2 0 0 2 2 2 1 PQQ-like domain PQQ PF01011.21 KXS12203.1 - 0.12 12.3 0.2 1.2 9.2 0.4 2.4 2 0 0 2 2 2 0 PQQ enzyme repeat His_Phos_1 PF00300.22 KXS12204.1 - 6.5e-10 39.0 0.0 3.4e-07 30.2 0.0 2.5 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) Mito_carr PF00153.27 KXS12205.1 - 4.9e-32 109.7 4.6 1.4e-19 69.8 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF4687 PF15747.5 KXS12206.1 - 0.3 11.6 3.1 1.7 9.2 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4687) 4HBT PF03061.22 KXS12207.1 - 1.8e-06 28.2 0.0 3.1e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily zf-MYND PF01753.18 KXS12208.1 - 5e-10 39.3 15.1 6.9e-10 38.9 15.1 1.2 1 0 0 1 1 1 1 MYND finger Shisa PF13908.6 KXS12208.1 - 0.28 11.4 9.1 0.36 11.1 9.1 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator LRR_8 PF13855.6 KXS12209.1 - 1.8e-07 30.8 16.6 7.2e-05 22.5 1.6 3.7 2 1 2 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 KXS12209.1 - 1e-06 28.9 9.3 0.0026 18.1 0.7 3.3 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KXS12209.1 - 0.0015 18.8 2.3 33 5.6 0.0 4.8 3 1 0 3 3 3 1 Leucine Rich Repeat LRR_6 PF13516.6 KXS12209.1 - 0.33 11.1 3.2 7.6 6.9 0.0 3.5 4 0 0 4 4 4 0 Leucine Rich repeat zf-RING_2 PF13639.6 KXS12210.1 - 2e-10 40.8 2.5 2.9e-10 40.3 2.5 1.2 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KXS12210.1 - 7.8e-08 31.9 2.8 1.2e-07 31.3 2.8 1.3 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KXS12210.1 - 1.4e-06 28.1 3.5 2e-06 27.5 3.5 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KXS12210.1 - 2.4e-06 27.8 1.3 4.4e-06 26.9 1.3 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KXS12210.1 - 2.9e-05 24.0 3.7 5.5e-05 23.1 3.7 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KXS12210.1 - 4.7e-05 23.2 2.0 6.9e-05 22.6 2.0 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXS12210.1 - 0.0001 22.2 1.9 0.00015 21.6 1.9 1.3 1 0 0 1 1 1 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 KXS12210.1 - 0.00091 18.8 1.9 0.0015 18.1 1.9 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 KXS12210.1 - 0.029 14.2 2.1 0.045 13.6 2.1 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KXS12210.1 - 0.032 14.4 3.5 0.051 13.7 3.5 1.3 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 KXS12210.1 - 0.043 13.9 0.6 0.078 13.0 0.6 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger PHD PF00628.29 KXS12210.1 - 0.31 11.0 1.4 0.54 10.2 1.4 1.4 1 0 0 1 1 1 0 PHD-finger zf-C3H2C3 PF17122.5 KXS12210.1 - 0.56 10.3 2.9 1.1 9.4 2.9 1.5 1 1 0 1 1 1 0 Zinc-finger NmrA PF05368.13 KXS12211.1 - 1.2e-19 70.8 0.0 1.7e-19 70.3 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXS12211.1 - 2.6e-06 27.5 0.0 4.4e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding GHL6 PF14871.6 KXS12211.1 - 0.034 14.3 0.0 0.052 13.7 0.0 1.2 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase 6 MCM PF00493.23 KXS12213.1 - 9.1e-73 244.1 0.0 1.5e-72 243.3 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KXS12213.1 - 1e-23 83.5 0.1 2.1e-23 82.5 0.1 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KXS12213.1 - 1.9e-21 76.3 1.1 3.8e-21 75.3 0.4 2.0 2 0 0 2 2 2 1 MCM AAA-lid domain Mg_chelatase PF01078.21 KXS12213.1 - 2.3e-08 33.7 0.2 0.00013 21.4 0.0 2.7 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KXS12213.1 - 9.6e-07 28.9 0.0 2.7e-06 27.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 KXS12213.1 - 0.00057 19.6 0.1 0.068 12.9 0.0 2.2 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_3 PF07726.11 KXS12213.1 - 0.001 18.9 0.0 0.0023 17.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KXS12213.1 - 0.03 14.7 0.3 0.14 12.5 0.1 2.3 1 1 1 2 2 2 0 AAA ATPase domain AAA_30 PF13604.6 KXS12213.1 - 0.032 13.9 0.5 0.11 12.3 0.5 1.8 1 1 0 1 1 1 0 AAA domain Glyco_transf_28 PF03033.20 KXS12214.1 - 1.2e-17 64.2 0.0 2.8e-17 63.1 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 KXS12214.1 - 0.00027 19.9 0.1 0.00054 18.9 0.1 1.4 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase GRAM PF02893.20 KXS12214.1 - 0.15 11.9 0.0 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 GRAM domain MFS_1 PF07690.16 KXS12216.1 - 3.8e-23 82.0 26.8 3.8e-23 82.0 26.8 2.0 1 1 0 2 2 2 2 Major Facilitator Superfamily PhoR PF11808.8 KXS12216.1 - 0.1 13.0 0.3 0.1 13.0 0.3 4.6 5 0 0 5 5 5 0 Phosphate regulon sensor protein PhoR DUF21 PF01595.20 KXS12216.1 - 7.7 6.2 9.9 0.22 11.2 1.4 2.6 3 0 0 3 3 3 0 Cyclin M transmembrane N-terminal domain Hemerythrin PF01814.23 KXS12218.1 - 1.8e-09 38.3 4.2 4e-05 24.3 2.3 2.4 2 0 0 2 2 2 2 Hemerythrin HHE cation binding domain GST_N_3 PF13417.6 KXS12218.1 - 4.2e-09 36.7 0.0 9.7e-09 35.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KXS12218.1 - 1e-07 32.1 0.0 2.3e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KXS12218.1 - 1.5e-06 28.1 0.0 4.2e-06 26.7 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KXS12218.1 - 0.00048 20.4 0.0 0.0015 18.8 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 KXS12218.1 - 0.012 15.3 0.0 0.027 14.2 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF3889 PF13028.6 KXS12218.1 - 0.063 13.2 0.0 0.19 11.7 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3889) GST_C PF00043.25 KXS12218.1 - 0.095 12.9 0.0 0.29 11.4 0.0 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain P53_TAD PF08563.11 KXS12218.1 - 0.1 12.1 0.2 0.19 11.3 0.2 1.4 1 0 0 1 1 1 0 P53 transactivation motif FAA_hydrolase_N PF09298.11 KXS12218.1 - 0.12 12.5 0.1 4.4 7.5 0.0 2.5 2 0 0 2 2 2 0 Fumarylacetoacetase N-terminal CALCOCO1 PF07888.11 KXS12223.1 - 0.011 14.6 0.3 0.017 14.0 0.3 1.2 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like CLZ PF16526.5 KXS12223.1 - 0.044 14.1 2.8 6.7 7.2 0.3 3.0 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels TPR_MLP1_2 PF07926.12 KXS12223.1 - 0.049 13.7 1.5 0.11 12.6 1.5 1.5 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Pox_A_type_inc PF04508.12 KXS12223.1 - 0.066 13.1 0.8 0.43 10.5 0.0 2.9 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat PhoU_div PF01865.16 KXS12223.1 - 0.11 11.7 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF47 Baculo_PEP_C PF04513.12 KXS12223.1 - 0.12 12.4 0.4 23 5.0 0.0 2.5 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus EamA PF00892.20 KXS12224.1 - 7.1e-18 65.1 36.2 3.1e-07 30.7 7.7 3.1 3 0 0 3 3 3 3 EamA-like transporter family SLC35F PF06027.12 KXS12224.1 - 7.8e-06 25.6 11.3 2.4e-05 24.0 9.3 2.4 2 1 0 2 2 2 1 Solute carrier family 35 PUNUT PF16913.5 KXS12224.1 - 2.9e-05 23.5 3.9 2.9e-05 23.5 3.9 1.9 2 1 0 3 3 3 1 Purine nucleobase transmembrane transport TPT PF03151.16 KXS12224.1 - 0.0004 19.8 2.0 0.0004 19.8 2.0 2.6 3 0 0 3 3 3 1 Triose-phosphate Transporter family UAA PF08449.11 KXS12224.1 - 0.16 11.2 10.6 0.043 13.0 7.5 1.6 2 1 0 2 2 2 0 UAA transporter family CoA_binding_3 PF13727.6 KXS12224.1 - 0.26 11.3 0.1 0.26 11.3 0.1 2.3 3 0 0 3 3 3 0 CoA-binding domain CD20 PF04103.15 KXS12224.1 - 1 9.4 8.4 0.045 13.8 2.2 2.0 2 0 0 2 2 2 0 CD20-like family ILVD_EDD PF00920.21 KXS12226.1 - 9.4e-206 684.4 0.3 1.1e-205 684.2 0.3 1.0 1 0 0 1 1 1 1 Dehydratase family DNA_binding_1 PF01035.20 KXS12226.1 - 0.19 11.9 0.0 28 4.9 0.0 2.6 2 0 0 2 2 2 0 6-O-methylguanine DNA methyltransferase, DNA binding domain AMP-binding PF00501.28 KXS12227.1 - 3.5e-56 190.6 0.0 4.7e-56 190.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXS12227.1 - 4.7e-15 56.3 0.8 1.5e-14 54.7 0.3 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain dCMP_cyt_deam_1 PF00383.23 KXS12228.1 - 8.9e-15 54.4 1.1 1.2e-14 54.0 1.1 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 KXS12228.1 - 1.4e-09 38.3 2.4 1.5e-07 31.7 0.5 2.2 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.6 KXS12228.1 - 0.07 12.7 1.2 2.4 7.7 0.1 2.6 2 1 0 2 2 2 0 A distinct subfamily of CDD/CDA-like deaminases COX16 PF14138.6 KXS12229.1 - 5e-20 71.8 0.4 5.9e-20 71.6 0.4 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 DHDPS PF00701.22 KXS12230.1 - 1.4e-31 109.3 0.0 1e-30 106.5 0.0 1.9 2 0 0 2 2 2 1 Dihydrodipicolinate synthetase family GATase PF00117.28 KXS12231.1 - 7.5e-11 42.2 0.0 1e-10 41.7 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KXS12231.1 - 0.00013 21.8 2.0 0.0038 17.0 2.0 2.7 1 1 0 1 1 1 1 Peptidase C26 Hemerythrin PF01814.23 KXS12232.1 - 1.5e-12 48.3 0.2 8.1e-09 36.2 0.0 2.2 1 1 1 2 2 2 2 Hemerythrin HHE cation binding domain GATase PF00117.28 KXS12232.1 - 3.2e-09 36.8 0.0 5.1e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KXS12232.1 - 0.00035 20.4 0.2 0.011 15.5 0.2 2.7 1 1 0 2 2 2 1 Peptidase C26 Carboxyl_trans PF01039.22 KXS12233.1 - 3.9e-75 253.4 0.0 5.3e-75 252.9 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain SBP_bac_3 PF00497.20 KXS12234.1 - 1e-66 224.6 0.0 1.4e-32 113.0 0.0 2.0 2 0 0 2 2 2 2 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.9 KXS12234.1 - 0.0016 18.7 0.0 0.45 10.7 0.0 2.5 2 0 0 2 2 2 2 Ligated ion channel L-glutamate- and glycine-binding site NMT1 PF09084.11 KXS12234.1 - 0.02 14.8 0.2 0.13 12.2 0.1 2.2 2 0 0 2 2 2 0 NMT1/THI5 like Phosphonate-bd PF12974.7 KXS12234.1 - 0.034 13.7 0.1 2.3 7.7 0.0 3.2 3 0 0 3 3 3 0 ABC transporter, phosphonate, periplasmic substrate-binding protein DUF746 PF05344.11 KXS12234.1 - 0.065 13.1 0.3 5.9 6.8 0.1 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF746) MG2 PF01835.19 KXS12234.1 - 0.072 13.5 0.0 18 5.9 0.0 2.3 2 0 0 2 2 2 0 MG2 domain PSII_Pbs31 PF18240.1 KXS12234.1 - 0.086 13.3 0.5 7.6 7.0 0.3 2.4 2 0 0 2 2 2 0 Photosystem II Psb31 protein Put_DNA-bind_N PF06971.13 KXS12234.1 - 0.14 12.2 0.0 30 4.7 0.0 2.5 2 0 0 2 2 2 0 Putative DNA-binding protein N-terminus Gln-synt_C PF00120.24 KXS12235.1 - 4.9e-83 279.0 0.0 6.3e-83 278.6 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain adh_short_C2 PF13561.6 KXS12240.1 - 6.3e-42 143.7 0.0 9.7e-42 143.1 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXS12240.1 - 1.1e-40 139.1 0.1 1.4e-40 138.8 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXS12240.1 - 0.0091 15.9 0.7 0.026 14.4 0.7 1.8 1 1 0 1 1 1 1 KR domain Heme_oxygenase PF01126.20 KXS12241.1 - 2.3e-40 138.6 0.0 3.8e-40 137.9 0.0 1.3 1 1 0 1 1 1 1 Heme oxygenase PaaA_PaaC PF05138.12 KXS12241.1 - 0.05 12.8 0.5 15 4.6 0.0 2.9 3 0 0 3 3 3 0 Phenylacetic acid catabolic protein Jiraiya PF15038.6 KXS12242.1 - 0.074 12.5 0.4 0.091 12.2 0.4 1.2 1 0 0 1 1 1 0 Jiraiya zf-C2H2 PF00096.26 KXS12243.1 - 1.6e-13 50.3 10.7 1.5e-06 28.3 0.7 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXS12243.1 - 4.4e-10 39.5 10.7 0.0012 19.5 0.4 3.2 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KXS12243.1 - 3.1e-05 24.2 4.4 0.033 14.6 0.1 2.8 3 1 0 3 3 2 2 Zinc-finger double domain zf_ZIC PF18366.1 KXS12243.1 - 0.00014 21.9 1.1 0.12 12.5 0.0 2.6 1 1 1 2 2 2 2 Zic proteins zinc finger domain zf-C2H2_8 PF15909.5 KXS12243.1 - 0.00019 21.7 1.0 0.0011 19.3 1.0 1.9 1 1 0 1 1 1 1 C2H2-type zinc ribbon FOXP-CC PF16159.5 KXS12243.1 - 0.00034 21.2 3.7 0.07 13.8 0.2 2.2 1 1 1 2 2 2 2 FOXP coiled-coil domain zf-H2C2_5 PF13909.6 KXS12243.1 - 0.0013 18.4 1.0 0.14 11.9 0.2 2.3 2 0 0 2 2 2 1 C2H2-type zinc-finger domain zf-Di19 PF05605.12 KXS12243.1 - 0.01 16.1 3.5 0.1 12.9 0.9 2.1 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-BED PF02892.15 KXS12243.1 - 0.025 14.6 6.3 0.41 10.7 2.2 3.0 1 1 2 3 3 3 0 BED zinc finger zf-C2H2_aberr PF17017.5 KXS12243.1 - 0.04 14.1 0.7 0.11 12.6 0.1 1.9 1 1 1 2 2 2 0 Aberrant zinc-finger zf-CGNR PF11706.8 KXS12243.1 - 0.041 13.7 1.0 2 8.3 0.2 2.5 2 0 0 2 2 2 0 CGNR zinc finger SpdB PF05122.13 KXS12243.1 - 0.047 13.8 8.0 1.1 9.5 0.4 3.0 2 1 1 3 3 3 0 Mobile element transfer protein IBR PF01485.21 KXS12243.1 - 0.08 13.2 3.5 0.2 11.9 0.4 2.1 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain CHORD PF04968.12 KXS12243.1 - 0.1 13.3 6.1 6 7.7 3.4 2.6 2 1 0 2 2 2 0 CHORD Ogr_Delta PF04606.12 KXS12243.1 - 0.12 12.3 2.7 3.1 7.8 0.1 2.9 3 0 0 3 3 3 0 Ogr/Delta-like zinc finger zf-C2H2_6 PF13912.6 KXS12243.1 - 0.18 11.9 3.8 2.6 8.1 0.4 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger Zn_clus PF00172.18 KXS12244.1 - 3.4e-11 43.1 13.8 4e-11 42.9 13.8 1.1 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXS12245.1 - 1.1e-05 24.7 0.2 1.4e-05 24.2 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain CCDC23 PF15674.5 KXS12247.1 - 0.67 10.0 3.9 0.19 11.8 0.5 1.8 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 23 Sporozoite_P67 PF05642.11 KXS12247.1 - 4.6 5.2 29.0 0.0055 14.9 5.9 2.2 2 0 0 2 2 2 0 Sporozoite P67 surface antigen bZIP_1 PF00170.21 KXS12247.1 - 6.1 7.0 13.2 13 6.0 13.2 1.4 1 1 0 1 1 1 0 bZIP transcription factor Pkinase PF00069.25 KXS12248.1 - 3.1e-74 249.7 0.0 5.1e-74 249.0 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS12248.1 - 2.8e-32 112.0 0.0 4.7e-21 75.3 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KXS12248.1 - 2e-07 30.6 0.1 0.3 10.4 0.0 3.1 3 0 0 3 3 3 3 Kinase-like APH PF01636.23 KXS12248.1 - 0.0025 17.8 0.3 1.4 8.8 0.0 2.6 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.14 KXS12248.1 - 0.042 13.2 0.0 0.072 12.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KXS12248.1 - 0.07 11.9 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Cyclase PF04199.13 KXS12249.1 - 2.5e-11 44.0 0.0 5.1e-11 43.0 0.0 1.5 1 1 0 1 1 1 1 Putative cyclase Aa_trans PF01490.18 KXS12250.1 - 5e-33 114.4 1.3 4.7e-18 65.1 0.0 2.3 1 1 1 2 2 2 2 Transmembrane amino acid transporter protein DUF202 PF02656.15 KXS12250.1 - 0.069 13.6 0.1 0.069 13.6 0.1 4.3 4 3 0 4 4 4 0 Domain of unknown function (DUF202) MOSC_N PF03476.16 KXS12252.1 - 1.2e-22 80.1 0.0 2.3e-22 79.1 0.0 1.5 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.17 KXS12252.1 - 8.2e-16 58.2 0.0 1.4e-15 57.5 0.0 1.4 1 0 0 1 1 1 1 MOSC domain Fungal_trans PF04082.18 KXS12253.1 - 2.8e-19 69.2 0.0 4.2e-19 68.6 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain ORC6 PF05460.13 KXS12253.1 - 0.29 10.4 3.1 0.44 9.8 3.1 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) AT_hook PF02178.19 KXS12253.1 - 0.4 10.7 6.0 1.2 9.2 6.0 1.8 1 0 0 1 1 1 0 AT hook motif Na_H_Exchanger PF00999.21 KXS12254.1 - 5.2e-57 193.4 38.2 6.4e-57 193.1 38.2 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF3852 PF12963.7 KXS12254.1 - 2 8.8 10.3 2.5 8.5 2.1 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3852) TPP_enzyme_N PF02776.18 KXS12255.1 - 1.7e-56 190.5 0.1 4e-56 189.3 0.1 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KXS12255.1 - 8.4e-53 178.3 0.3 3.7e-51 172.9 0.1 2.8 3 1 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KXS12255.1 - 1.4e-41 141.4 0.1 3.5e-41 140.2 0.1 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain DUF1910 PF08928.10 KXS12255.1 - 0.15 12.0 0.1 0.35 10.9 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1910) Epimerase PF01370.21 KXS12256.1 - 0.062 12.8 0.0 0.15 11.5 0.0 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Rieske PF00355.26 KXS12258.1 - 3e-11 43.1 0.1 4.2e-11 42.6 0.1 1.2 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.14 KXS12258.1 - 5.8e-08 33.1 0.5 1.4e-07 31.9 0.5 1.6 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region zf-C2H2 PF00096.26 KXS12259.1 - 1.5e-09 37.8 6.3 7.7e-05 22.9 0.2 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXS12259.1 - 3.7e-07 30.4 5.2 0.0026 18.5 0.9 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KXS12259.1 - 0.1 12.9 1.1 9.8 6.6 0.1 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KXS12259.1 - 0.46 10.5 5.2 16 5.7 0.0 2.9 2 1 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KXS12259.1 - 1.4 9.5 10.5 9.6 6.8 0.4 3.4 3 0 0 3 3 3 0 Zinc-finger double domain RRM_1 PF00076.22 KXS12261.1 - 4.4e-31 106.5 0.0 5.4e-15 55.0 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 KXS12261.1 - 0.031 14.1 0.0 5.5 6.8 0.0 2.8 3 0 0 3 3 3 0 Rrp7 RRM-like N-terminal domain RRM_occluded PF16842.5 KXS12261.1 - 0.1 12.4 0.0 4 7.4 0.0 2.2 2 0 0 2 2 2 0 Occluded RNA-recognition motif Limkain-b1 PF11608.8 KXS12261.1 - 0.11 12.6 0.2 18 5.5 0.0 2.7 2 2 0 2 2 2 0 Limkain b1 Pro_dh PF01619.18 KXS12262.1 - 3.6e-60 204.0 0.0 8.3e-60 202.8 0.0 1.5 2 0 0 2 2 2 1 Proline dehydrogenase adh_short PF00106.25 KXS12263.1 - 7.6e-11 41.8 7.1 1.1e-10 41.3 7.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXS12263.1 - 7.3e-10 38.8 8.6 1.2e-09 38.1 8.6 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXS12263.1 - 0.00084 19.3 1.0 0.00084 19.3 1.0 1.7 2 0 0 2 2 2 1 KR domain Septin PF00735.18 KXS12264.1 - 7.5e-97 324.0 0.0 8.6e-97 323.8 0.0 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KXS12264.1 - 6.5e-07 29.4 0.0 1.7e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KXS12264.1 - 1.6e-05 24.9 0.2 4.6e-05 23.4 0.1 1.7 2 0 0 2 2 2 1 RsgA GTPase T2SSE PF00437.20 KXS12264.1 - 1.6e-05 24.1 0.0 3.1e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein Dynamin_N PF00350.23 KXS12264.1 - 6.5e-05 23.0 0.0 0.17 11.9 0.0 2.3 1 1 1 2 2 2 2 Dynamin family AIG1 PF04548.16 KXS12264.1 - 0.00034 20.0 0.0 0.00051 19.4 0.0 1.2 1 0 0 1 1 1 1 AIG1 family Roc PF08477.13 KXS12264.1 - 0.0012 19.0 0.0 0.0021 18.3 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 KXS12264.1 - 0.0018 18.8 0.0 0.0028 18.2 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_7 PF12775.7 KXS12264.1 - 0.0022 17.5 0.0 0.0036 16.8 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region DUF815 PF05673.13 KXS12264.1 - 0.0029 16.8 0.0 0.0045 16.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) cobW PF02492.19 KXS12264.1 - 0.0037 16.9 0.2 0.012 15.2 0.2 2.0 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.6 KXS12264.1 - 0.0042 16.8 0.0 0.0094 15.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 KXS12264.1 - 0.0042 17.4 0.1 0.011 16.0 0.1 1.9 1 1 0 1 1 1 1 AAA domain GTP_EFTU PF00009.27 KXS12264.1 - 0.0047 16.5 0.1 0.038 13.5 0.1 2.3 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain G-alpha PF00503.20 KXS12264.1 - 0.0048 16.1 0.0 0.0064 15.7 0.0 1.2 1 0 0 1 1 1 1 G-protein alpha subunit AAA_16 PF13191.6 KXS12264.1 - 0.0055 17.1 0.0 0.009 16.4 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain FtsK_SpoIIIE PF01580.18 KXS12264.1 - 0.0073 15.7 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_33 PF13671.6 KXS12264.1 - 0.0078 16.4 0.2 0.02 15.1 0.2 1.5 1 1 0 1 1 1 1 AAA domain SRPRB PF09439.10 KXS12264.1 - 0.011 15.2 0.0 0.017 14.5 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit CLP1_P PF16575.5 KXS12264.1 - 0.011 15.6 0.1 15 5.3 0.0 3.1 3 0 0 3 3 3 0 mRNA cleavage and polyadenylation factor CLP1 P-loop PduV-EutP PF10662.9 KXS12264.1 - 0.012 15.3 0.0 0.086 12.6 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.12 KXS12264.1 - 0.014 14.8 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Mg_chelatase PF01078.21 KXS12264.1 - 0.015 14.7 0.0 0.025 14.0 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ATP_bind_1 PF03029.17 KXS12264.1 - 0.017 14.9 0.2 0.16 11.7 0.1 2.2 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_5 PF07728.14 KXS12264.1 - 0.018 15.1 0.0 0.029 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_23 PF13476.6 KXS12264.1 - 0.018 15.6 0.0 0.024 15.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.6 KXS12264.1 - 0.026 14.3 0.0 0.037 13.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Pox_A32 PF04665.12 KXS12264.1 - 0.032 13.7 0.0 0.053 13.0 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein SRP54 PF00448.22 KXS12264.1 - 0.035 13.7 0.0 0.064 12.9 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain TsaE PF02367.17 KXS12264.1 - 0.049 13.6 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 KXS12264.1 - 0.057 13.1 0.0 0.093 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KXS12264.1 - 0.085 12.4 0.0 0.17 11.4 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KXS12264.1 - 0.09 12.5 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 KXS12264.1 - 0.1 12.0 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein AAA PF00004.29 KXS12264.1 - 0.13 12.7 0.0 0.21 12.0 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KXS12264.1 - 0.15 12.4 0.0 0.26 11.7 0.0 1.4 1 0 0 1 1 1 0 RNA helicase NB-ARC PF00931.22 KXS12264.1 - 0.2 10.8 0.0 0.36 10.0 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain DEC-1_N PF04625.13 KXS12264.1 - 2.1 7.2 3.8 2.6 7.0 3.8 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region F-box-like PF12937.7 KXS12265.1 - 0.00052 19.8 0.6 0.0079 16.1 1.5 2.2 2 0 0 2 2 2 1 F-box-like Zip PF02535.22 KXS12265.1 - 2.9 7.0 10.4 5.8 6.0 10.4 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter BatA PF07584.11 KXS12269.1 - 0.018 15.4 0.3 0.049 14.0 0.3 1.8 1 0 0 1 1 1 0 Aerotolerance regulator N-terminal DUF4112 PF13430.6 KXS12269.1 - 0.11 12.7 4.2 0.77 10.1 0.1 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF4112) His_Phos_2 PF00328.22 KXS12270.1 - 2.3e-16 60.2 0.1 4.4e-12 46.0 0.5 2.9 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) zf-C2H2_11 PF16622.5 KXS12271.1 - 0.0048 16.6 0.3 0.0098 15.6 0.3 1.4 1 0 0 1 1 1 1 zinc-finger C2H2-type zf-C2H2 PF00096.26 KXS12271.1 - 0.009 16.4 1.2 0.023 15.2 1.2 1.7 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-LYAR PF08790.11 KXS12271.1 - 0.039 13.9 0.2 0.073 13.0 0.2 1.5 1 0 0 1 1 1 0 LYAR-type C2HC zinc finger zf-C2H2_4 PF13894.6 KXS12271.1 - 0.077 13.9 0.5 0.2 12.6 0.5 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger F-box PF00646.33 KXS12274.1 - 2.8e-05 23.9 0.7 4e-05 23.4 0.7 1.2 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KXS12274.1 - 0.0021 17.9 0.7 0.003 17.4 0.7 1.2 1 0 0 1 1 1 1 F-box-like Phytoreo_P8 PF07124.11 KXS12274.1 - 0.064 12.2 0.0 0.069 12.1 0.0 1.0 1 0 0 1 1 1 0 Phytoreovirus outer capsid protein P8 F-box_4 PF15966.5 KXS12274.1 - 0.12 12.3 0.1 0.15 12.0 0.1 1.2 1 0 0 1 1 1 0 F-box Got1 PF04178.12 KXS12275.1 - 2.6e-33 114.8 17.5 1.2e-32 112.7 16.7 1.9 1 1 1 2 2 2 2 Got1/Sft2-like family PMT PF02366.18 KXS12276.1 - 4.3e-80 268.8 22.4 4.3e-80 268.8 22.4 1.5 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 KXS12276.1 - 7.3e-53 179.1 9.8 7.3e-53 179.1 9.8 3.4 3 1 0 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 KXS12276.1 - 2.3e-29 102.6 1.2 8.8e-22 77.8 0.1 2.2 2 0 0 2 2 2 2 MIR domain PMT_2 PF13231.6 KXS12276.1 - 4.1 7.6 29.9 0.036 14.3 15.1 3.7 3 1 1 4 4 4 0 Dolichyl-phosphate-mannose-protein mannosyltransferase Alg6_Alg8 PF03155.15 KXS12280.1 - 1.8e-145 485.6 24.1 2.1e-145 485.4 24.1 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family TauD PF02668.16 KXS12283.1 - 6.8e-63 213.0 3.6 8.7e-63 212.6 3.6 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family AMP-binding PF00501.28 KXS12284.1 - 8.8e-91 304.6 0.1 1.2e-90 304.2 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXS12284.1 - 0.00048 21.0 0.0 0.0013 19.7 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Carboxyl_trans PF01039.22 KXS12285.1 - 7.7e-144 480.0 0.0 1e-143 479.6 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain ECH_1 PF00378.20 KXS12285.1 - 0.26 10.6 0.7 0.78 9.0 0.0 1.9 2 0 0 2 2 2 0 Enoyl-CoA hydratase/isomerase Peptidase_M48 PF01435.18 KXS12286.1 - 3e-29 102.2 0.0 4.9e-29 101.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M48 DUF5345 PF17280.2 KXS12286.1 - 0.099 12.6 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5345) TatD_DNase PF01026.21 KXS12287.1 - 2.2e-21 76.4 0.4 1.5e-18 67.1 0.1 2.5 1 1 1 2 2 2 2 TatD related DNase SH3_9 PF14604.6 KXS12288.1 - 1.4e-07 31.3 0.0 2.1e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXS12288.1 - 5e-05 22.8 0.0 0.0001 21.8 0.0 1.5 1 0 0 1 1 1 1 SH3 domain Ion_trans PF00520.31 KXS12289.1 - 8.7e-25 87.4 17.4 1.2e-24 86.9 17.4 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 KXS12289.1 - 4.8e-09 36.1 8.4 4.8e-09 36.1 8.4 2.4 2 1 0 2 2 2 1 Ion channel Lig_chan PF00060.26 KXS12289.1 - 0.077 12.8 0.3 0.077 12.8 0.3 2.2 2 0 0 2 2 2 0 Ligand-gated ion channel PhoD PF09423.10 KXS12290.1 - 0.00013 21.2 0.0 0.00017 20.7 0.0 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase CDC45 PF02724.14 KXS12294.1 - 1.2 7.3 5.8 1.1 7.5 5.8 1.0 1 0 0 1 1 1 0 CDC45-like protein TFIID_20kDa PF03847.13 KXS12297.1 - 1.7e-14 54.1 0.0 3.5e-14 53.0 0.0 1.6 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A ABM PF03992.16 KXS12298.1 - 9.5e-17 60.9 0.1 1.1e-16 60.7 0.1 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Dabb PF07876.12 KXS12298.1 - 0.12 13.0 0.0 0.15 12.7 0.0 1.1 1 0 0 1 1 1 0 Stress responsive A/B Barrel Domain Acyl-CoA_dh_1 PF00441.24 KXS12299.1 - 4.9e-30 104.7 0.2 8.9e-30 103.9 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.28 KXS12299.1 - 1.3e-21 76.5 0.1 4.2e-21 74.9 0.0 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.19 KXS12299.1 - 3.7e-18 65.5 0.2 7.9e-18 64.5 0.2 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KXS12299.1 - 0.00011 22.8 0.0 0.00035 21.2 0.0 1.9 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KXS12299.1 - 0.00019 21.7 0.0 0.00036 20.8 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain adh_short PF00106.25 KXS12301.1 - 1.3e-47 161.8 2.7 1.6e-47 161.5 2.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXS12301.1 - 6.6e-33 114.2 0.3 8.1e-33 113.9 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXS12301.1 - 5.8e-07 29.6 0.6 1e-06 28.8 0.6 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KXS12301.1 - 1.1e-05 25.0 0.2 1.5e-05 24.6 0.2 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 KXS12301.1 - 0.0001 21.8 0.0 0.0037 16.7 0.0 2.0 1 1 1 2 2 2 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.6 KXS12301.1 - 0.00027 20.9 0.4 0.00034 20.5 0.4 1.3 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KXS12301.1 - 0.086 12.2 0.2 0.12 11.7 0.2 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KXS12301.1 - 0.11 11.5 0.1 0.15 11.2 0.1 1.1 1 0 0 1 1 1 0 RmlD substrate binding domain Hemerythrin PF01814.23 KXS12302.1 - 1.6e-06 28.8 0.1 2.4e-06 28.2 0.1 1.3 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain zf-C2H2 PF00096.26 KXS12306.1 - 1e-12 47.8 16.4 3.3e-05 24.1 1.2 3.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KXS12306.1 - 3.5e-11 43.0 4.9 1.1e-09 38.2 0.2 2.6 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KXS12306.1 - 7.1e-11 42.0 14.0 0.0028 18.4 0.6 3.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KXS12306.1 - 0.00076 19.4 4.5 3.1 7.9 0.4 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KXS12306.1 - 0.074 13.4 2.6 9.1 6.7 0.3 3.2 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf_ZIC PF18366.1 KXS12306.1 - 0.089 12.9 3.4 0.35 11.0 0.4 2.3 2 0 0 2 2 2 0 Zic proteins zinc finger domain YdjO PF14169.6 KXS12306.1 - 0.092 12.5 0.7 0.28 10.9 0.7 1.9 1 1 0 1 1 1 0 Cold-inducible protein YdjO zf-LYAR PF08790.11 KXS12306.1 - 0.14 12.0 0.2 0.14 12.0 0.2 2.9 2 1 1 3 3 3 0 LYAR-type C2HC zinc finger Nop25 PF09805.9 KXS12307.1 - 3e-19 69.8 15.1 3e-19 69.8 15.1 2.1 1 1 0 2 2 2 1 Nucleolar protein 12 (25kDa) ALC PF17527.2 KXS12307.1 - 0.04 13.6 0.6 0.071 12.7 0.6 1.3 1 0 0 1 1 1 0 Phage ALC protein zf-C2H2 PF00096.26 KXS12308.1 - 0.0018 18.7 1.2 0.0058 17.0 1.2 2.0 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXS12308.1 - 0.024 15.4 0.5 0.08 13.8 0.5 2.0 1 0 0 1 1 1 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KXS12308.1 - 0.1 13.1 0.3 0.1 13.1 0.3 1.9 2 0 0 2 2 2 0 Zinc-finger double domain Dimer_Tnp_hAT PF05699.14 KXS12309.1 - 1.2e-18 66.7 0.0 1.4e-18 66.5 0.0 1.1 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region F-box PF00646.33 KXS12310.1 - 0.00021 21.1 0.1 0.0007 19.4 0.1 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KXS12310.1 - 0.025 14.4 0.3 0.025 14.4 0.3 2.1 2 0 0 2 2 2 0 F-box-like HHV-5_US34A PF17087.5 KXS12311.1 - 0.24 11.6 0.3 0.95 9.7 0.3 2.0 1 0 0 1 1 1 0 Herpesvirus US34A protein family Metallophos PF00149.28 KXS12312.1 - 9.4e-34 117.7 0.1 1.2e-33 117.4 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase FMO-like PF00743.19 KXS12313.1 - 8.1e-06 24.5 0.0 1.1e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KXS12313.1 - 1.5e-05 24.3 0.0 3.6e-05 23.1 0.0 1.6 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) K_oxygenase PF13434.6 KXS12314.1 - 0.0084 15.3 0.0 0.057 12.6 0.0 1.9 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KXS12314.1 - 0.033 13.4 0.1 0.84 8.8 0.1 2.1 1 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KXS12314.1 - 0.038 12.4 0.0 5.5 5.3 0.0 2.1 2 0 0 2 2 2 0 Flavin-binding monooxygenase-like Shikimate_DH PF01488.20 KXS12314.1 - 0.047 13.8 0.1 0.11 12.6 0.0 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 KXS12314.1 - 0.053 14.0 0.0 0.08 13.4 0.0 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox PF00070.27 KXS12314.1 - 0.14 12.7 0.0 0.27 11.8 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Catalase PF00199.19 KXS12315.1 - 3.9e-90 302.7 0.0 5.2e-90 302.3 0.0 1.2 1 0 0 1 1 1 1 Catalase Catalase_C PF18011.1 KXS12315.1 - 4.5e-21 75.1 6.5 6.9e-20 71.2 4.4 2.8 2 1 0 2 2 2 1 C-terminal domain found in long catalases Catalase-rel PF06628.12 KXS12315.1 - 1.1e-18 67.2 0.1 2.4e-18 66.1 0.1 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive DJ-1_PfpI PF01965.24 KXS12315.1 - 1.1e-14 54.6 1.0 1.6e-14 54.0 1.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family Glyoxalase PF00903.25 KXS12316.1 - 1.4e-06 28.5 0.0 4.7e-06 26.8 0.0 1.7 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KXS12316.1 - 0.0005 20.3 0.0 0.0073 16.6 0.0 2.1 2 0 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 KXS12316.1 - 0.003 18.3 0.0 0.0066 17.2 0.0 1.5 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_3 PF13468.6 KXS12316.1 - 0.01 15.9 0.0 0.074 13.2 0.0 1.9 2 0 0 2 2 2 0 Glyoxalase-like domain Glyoxalase PF00903.25 KXS12317.1 - 2.6e-07 30.9 0.0 2e-06 28.0 0.0 2.2 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KXS12317.1 - 0.035 14.4 0.0 0.36 11.1 0.0 2.2 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 KXS12317.1 - 0.094 12.7 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Glyoxalase-like domain FMO-like PF00743.19 KXS12318.1 - 0.12 10.8 0.0 0.15 10.5 0.0 1.0 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like Hemerythrin PF01814.23 KXS12321.1 - 3e-05 24.6 0.1 5.1e-05 23.9 0.1 1.4 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain DUF2804 PF10974.8 KXS12322.1 - 2.9e-56 191.4 0.0 3.5e-56 191.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2804) AA_kinase PF00696.28 KXS12323.1 - 2.7e-39 135.2 0.5 2.7e-39 135.2 0.5 1.5 2 0 0 2 2 2 1 Amino acid kinase family PUA PF01472.20 KXS12323.1 - 2.7e-17 62.5 3.6 7.4e-17 61.1 3.6 1.8 1 0 0 1 1 1 1 PUA domain PUA_3 PF17785.1 KXS12323.1 - 0.0041 16.9 0.3 0.013 15.3 0.2 1.9 1 1 0 1 1 1 1 PUA-like domain Exo_endo_phos PF03372.23 KXS12324.1 - 0.00017 21.2 0.0 0.00032 20.3 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family VPDSG-CTERM PF18205.1 KXS12324.1 - 0.11 12.3 0.2 0.29 11.0 0.2 1.8 1 0 0 1 1 1 0 VPDSG-CTERM motif Pyridoxal_deC PF00282.19 KXS12325.1 - 8.6e-59 199.1 0.0 1.2e-58 198.7 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 KXS12325.1 - 0.024 13.9 0.0 0.069 12.4 0.0 1.7 2 1 0 2 2 2 0 Beta-eliminating lyase Aminotran_5 PF00266.19 KXS12325.1 - 0.046 12.7 0.0 0.086 11.8 0.0 1.5 1 0 0 1 1 1 0 Aminotransferase class-V Acyl-CoA_dh_1 PF00441.24 KXS12327.1 - 6.7e-26 91.3 0.0 1.1e-25 90.6 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KXS12327.1 - 2.3e-24 86.2 0.0 6.3e-24 84.8 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KXS12327.1 - 1.9e-20 72.8 0.0 3.3e-20 72.1 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KXS12327.1 - 1.6e-06 28.4 0.0 3e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Pantoate_transf PF02548.15 KXS12328.1 - 1.9e-99 332.3 0.1 2.3e-99 332.0 0.1 1.1 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 KXS12328.1 - 8.3e-05 22.1 0.0 0.00013 21.5 0.0 1.4 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Asp_Glu_race PF01177.22 KXS12328.1 - 0.0035 17.2 0.0 0.005 16.7 0.0 1.4 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase YceG PF02618.16 KXS12328.1 - 0.11 12.0 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 YceG-like family Hydrolase_4 PF12146.8 KXS12329.1 - 3.3e-08 33.1 2.1 0.089 12.0 0.1 3.1 2 1 1 3 3 3 3 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KXS12329.1 - 5.1e-08 32.9 0.6 0.0023 17.6 0.0 3.1 2 1 1 3 3 3 3 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXS12329.1 - 0.046 14.3 0.2 0.73 10.4 0.6 2.4 1 1 1 2 2 2 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KXS12329.1 - 0.071 12.6 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Acyl_transf_2 PF02273.15 KXS12329.1 - 0.15 11.3 0.1 7.5 5.7 0.0 2.1 2 0 0 2 2 2 0 Acyl transferase Epimerase PF01370.21 KXS12330.1 - 6.6e-10 38.8 0.0 9.1e-10 38.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXS12330.1 - 0.003 16.6 0.0 0.0045 16.0 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KXS12330.1 - 0.0045 16.9 0.1 2.7 7.8 0.0 2.4 2 0 0 2 2 2 2 NAD(P)H-binding MFS_1 PF07690.16 KXS12331.1 - 1.3e-30 106.5 43.8 4.9e-19 68.5 13.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXS12331.1 - 1.6e-06 27.3 29.5 0.00013 21.0 9.5 2.6 3 0 0 3 3 3 2 Sugar (and other) transporter DUF4538 PF15061.6 KXS12331.1 - 2.4 7.9 4.3 1.2 9.0 0.2 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4538) Annexin PF00191.20 KXS12332.1 - 4.1e-79 260.6 5.2 1.7e-23 82.4 0.0 4.0 4 0 0 4 4 4 4 Annexin OST-HTH PF12872.7 KXS12332.1 - 0.00055 19.7 0.0 4.4 7.2 0.0 4.0 4 0 0 4 4 4 2 OST-HTH/LOTUS domain YlbE PF14003.6 KXS12332.1 - 0.0058 17.0 0.0 0.43 11.0 0.0 3.2 3 0 0 3 3 3 1 YlbE-like protein Acetyltransf_11 PF13720.6 KXS12332.1 - 0.18 12.3 0.5 4.8 7.7 0.0 3.3 3 2 1 4 4 4 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 WD40 PF00400.32 KXS12333.1 - 2e-41 139.1 5.8 1.5e-06 28.8 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXS12333.1 - 6.5e-13 48.8 0.2 0.00076 19.7 0.0 4.5 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Gmad1 PF10647.9 KXS12333.1 - 0.00011 22.1 0.3 0.00086 19.1 0.0 2.4 2 1 1 3 3 3 1 Lipoprotein LpqB beta-propeller domain eIF2A PF08662.11 KXS12333.1 - 0.0022 17.9 0.1 1.2 8.9 0.0 3.1 2 1 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KXS12333.1 - 0.0068 15.4 0.0 9.3 5.1 0.0 3.8 2 1 2 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KXS12333.1 - 0.0092 15.9 0.8 25 4.9 0.0 4.0 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Nup160 PF11715.8 KXS12333.1 - 0.23 10.1 0.5 11 4.5 0.0 2.8 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Frtz PF11768.8 KXS12333.1 - 0.23 9.7 0.0 7 4.8 0.0 2.4 2 1 1 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz IQ PF00612.27 KXS12334.1 - 9.9e-16 56.0 10.4 2.8e-06 26.6 1.4 3.5 3 0 0 3 3 3 3 IQ calmodulin-binding motif KduI PF04962.12 KXS12334.1 - 0.046 13.0 0.5 0.069 12.5 0.5 1.3 1 0 0 1 1 1 0 KduI/IolB family RET_CLD3 PF17812.1 KXS12334.1 - 0.13 12.5 0.2 13 6.1 0.0 2.8 1 1 2 3 3 3 0 RET Cadherin like domain 3 AAA_16 PF13191.6 KXS12334.1 - 0.16 12.3 2.9 0.14 12.5 1.5 1.5 2 0 0 2 2 2 0 AAA ATPase domain CENP-S PF15630.6 KXS12335.1 - 1.5e-27 95.8 0.7 2.2e-27 95.2 0.7 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 KXS12335.1 - 3e-06 27.3 0.1 4.1e-06 26.9 0.1 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Bromo_TP PF07524.13 KXS12335.1 - 0.0027 17.7 0.5 0.0091 16.0 0.1 1.9 2 0 0 2 2 2 1 Bromodomain associated Histone PF00125.24 KXS12335.1 - 0.014 15.8 0.5 0.021 15.2 0.5 1.3 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KXS12335.1 - 0.016 15.3 0.1 0.022 14.8 0.1 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit VIT PF08487.10 KXS12336.1 - 9.9e-35 119.1 0.3 1.9e-34 118.2 0.3 1.5 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.6 KXS12336.1 - 2.8e-25 89.1 0.0 6.1e-25 88.0 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT_2 PF13757.6 KXS12336.1 - 7.3e-12 45.0 0.2 1.5e-11 44.0 0.2 1.5 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_2 PF13519.6 KXS12336.1 - 2.4e-10 41.0 0.0 5.6e-10 39.8 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 KXS12336.1 - 1.7e-09 38.2 0.0 3.5e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 KXS12336.1 - 0.065 12.6 0.0 0.15 11.4 0.0 1.6 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein HdeA PF06411.11 KXS12336.1 - 0.11 12.6 0.1 0.41 10.9 0.0 1.9 2 0 0 2 2 2 0 HdeA/HdeB family VIT PF08487.10 KXS12337.1 - 3.4e-25 88.4 0.7 5.8e-25 87.7 0.7 1.3 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VIT_2 PF13757.6 KXS12337.1 - 1e-11 44.5 0.5 1.8e-11 43.8 0.5 1.3 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain Not3 PF04065.15 KXS12338.1 - 8.8e-76 254.4 18.4 1.2e-75 253.9 18.4 1.2 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 KXS12338.1 - 4.2e-46 156.3 8.2 1.1e-45 155.0 8.2 1.7 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Syntaxin_2 PF14523.6 KXS12338.1 - 0.012 15.9 3.3 0.012 15.9 3.3 2.6 1 1 1 2 2 2 0 Syntaxin-like protein TT1725 PF18324.1 KXS12338.1 - 0.11 12.6 0.1 0.24 11.5 0.1 1.5 1 0 0 1 1 1 0 Hypothetical protein TT1725 Spc7 PF08317.11 KXS12338.1 - 0.19 10.5 21.2 0.19 10.6 6.7 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein NPV_P10 PF05531.12 KXS12338.1 - 0.32 11.5 8.3 22 5.6 4.5 3.7 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Exonuc_VII_S PF02609.16 KXS12338.1 - 1.7 8.7 9.5 20 5.3 0.1 4.2 4 0 0 4 4 4 0 Exonuclease VII small subunit Cep57_MT_bd PF06657.13 KXS12338.1 - 2.7 8.5 12.0 0.43 11.1 2.3 2.9 2 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DUF2203 PF09969.9 KXS12338.1 - 7.4 7.3 12.2 13 6.6 2.4 2.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Hemerythrin PF01814.23 KXS12341.1 - 5.4e-13 49.7 6.7 1.2e-12 48.5 6.7 1.6 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain GST_N_3 PF13417.6 KXS12341.1 - 5e-09 36.4 0.0 1.2e-08 35.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KXS12341.1 - 4e-08 33.4 0.0 8.3e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KXS12341.1 - 1.6e-05 24.8 0.0 7.6e-05 22.7 0.0 2.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KXS12341.1 - 0.00051 20.3 0.0 0.0016 18.7 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 KXS12341.1 - 0.075 13.3 0.1 0.27 11.5 0.1 1.9 1 0 0 1 1 1 0 Glutaredoxin TFIID_30kDa PF03540.13 KXS12342.1 - 5.6e-25 87.0 0.2 8.8e-25 86.4 0.2 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit TAF4 PF05236.14 KXS12342.1 - 0.058 13.1 0.4 0.12 12.1 0.1 1.5 1 1 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family RNA_pol_Rpc4 PF05132.14 KXS12343.1 - 8.7e-19 68.4 0.1 8.7e-19 68.4 0.1 2.8 2 1 0 2 2 2 1 RNA polymerase III RPC4 DUF5473 PF17567.2 KXS12343.1 - 2.8 8.3 8.8 6 7.2 5.8 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5473) Glyoxalase PF00903.25 KXS12344.1 - 2.1e-18 66.7 0.0 2.1e-11 44.1 0.0 2.4 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KXS12344.1 - 1.7e-10 41.1 0.0 0.00031 21.0 0.0 2.5 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 KXS12344.1 - 3.4e-08 33.8 0.0 0.018 15.2 0.0 3.5 1 1 1 2 2 2 2 Glyoxalase-like domain Glyoxalase_5 PF14696.6 KXS12344.1 - 2.3e-06 27.8 0.0 1.1e-05 25.6 0.0 2.1 3 0 0 3 3 3 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Ank PF00023.30 KXS12346.1 - 2.3e-08 34.1 0.2 0.00026 21.3 0.2 3.5 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 KXS12346.1 - 3.3e-05 23.9 0.3 0.008 16.6 0.1 3.3 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.7 KXS12346.1 - 3.7e-05 24.2 0.0 0.0011 19.5 0.0 2.6 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXS12346.1 - 0.021 15.4 0.0 2.4 8.9 0.0 3.2 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXS12346.1 - 0.15 12.4 0.1 12 6.3 0.0 3.1 3 0 0 3 3 3 0 Ankyrin repeats (many copies) SSP160 PF06933.11 KXS12346.1 - 2.9 6.0 13.0 4.6 5.3 13.0 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 MFS_1 PF07690.16 KXS12347.1 - 4e-25 88.5 33.3 4e-25 88.5 33.3 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF5453 PF17534.2 KXS12347.1 - 0.19 11.7 0.6 0.5 10.3 0.3 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5453) CoA_trans PF01144.23 KXS12348.1 - 8.8e-107 355.4 1.2 5.2e-70 235.2 0.1 2.2 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.6 KXS12348.1 - 0.051 13.5 0.0 0.087 12.8 0.0 1.3 1 0 0 1 1 1 0 Acetyl-CoA hydrolase/transferase C-terminal domain ICMT PF04140.14 KXS12349.1 - 1.3e-26 92.8 0.4 2.8e-26 91.8 0.4 1.5 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KXS12349.1 - 5.8e-09 36.3 2.0 5.8e-09 36.3 2.0 1.8 2 0 0 2 2 2 1 Phospholipid methyltransferase NnrU PF07298.11 KXS12349.1 - 0.004 16.7 2.4 0.004 16.7 2.4 1.5 1 1 0 1 1 1 1 NnrU protein Ofd1_CTDD PF10637.9 KXS12350.1 - 5.2e-82 275.0 0.0 2.9e-78 262.8 0.0 2.2 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 KXS12350.1 - 5.8e-26 91.0 0.0 1.2e-25 90.0 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 KXS12350.1 - 3.2e-13 50.4 0.0 8e-13 49.1 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Cwf_Cwc_15 PF04889.12 KXS12350.1 - 0.19 11.5 5.9 0.33 10.6 5.9 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RNA_pol_3_Rpc31 PF11705.8 KXS12350.1 - 1.3 9.3 10.1 2.6 8.2 10.1 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 tRNA-synt_1b PF00579.25 KXS12351.1 - 1e-69 235.1 0.0 1.4e-69 234.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) TyrRSs_C PF16714.5 KXS12351.1 - 2e-05 24.4 0.7 0.0028 17.5 0.7 2.5 1 1 0 1 1 1 1 Tyrosyl-tRNA synthetase C-terminal domain S4 PF01479.25 KXS12351.1 - 0.0027 17.4 0.0 0.0051 16.5 0.0 1.5 1 0 0 1 1 1 1 S4 domain Methyltransf_16 PF10294.9 KXS12352.1 - 1.9e-18 66.8 0.0 4e-18 65.7 0.0 1.5 1 1 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 KXS12352.1 - 0.059 12.9 0.1 0.25 10.9 0.1 1.9 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_31 PF13847.6 KXS12352.1 - 0.1 12.4 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 KXS12352.1 - 0.15 12.9 0.0 0.27 12.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.6 KXS12352.1 - 0.15 12.0 0.0 0.24 11.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Mre11_DNA_bind PF04152.14 KXS12353.1 - 2e-46 158.4 0.1 2e-46 158.4 0.1 2.1 2 0 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 KXS12353.1 - 5.3e-09 36.9 3.4 3.7e-08 34.1 3.4 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KXS12353.1 - 0.0019 18.4 0.2 0.089 13.0 0.0 3.0 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain FKBP_N PF01346.18 KXS12353.1 - 0.63 11.0 4.6 2.1 9.3 4.6 1.8 1 0 0 1 1 1 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase UPF0020 PF01170.18 KXS12354.1 - 1.4e-13 51.0 0.0 6.1e-13 48.9 0.0 1.9 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 AviRa PF11599.8 KXS12354.1 - 0.02 14.4 0.0 0.038 13.5 0.0 1.3 1 0 0 1 1 1 0 RRNA methyltransferase AviRa Nodulin_late PF07127.11 KXS12355.1 - 0.035 14.4 0.0 0.035 14.4 0.0 1.7 2 0 0 2 2 2 0 Late nodulin protein DUF2771 PF10969.8 KXS12357.1 - 0.069 13.2 0.1 0.11 12.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2771) DUF4381 PF14316.6 KXS12357.1 - 0.12 12.7 0.4 0.3 11.3 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF5134 PF17197.4 KXS12357.1 - 2.4 8.1 5.2 0.45 10.4 0.8 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF5134) FMN_bind_2 PF04299.12 KXS12359.1 - 4.4e-52 176.2 0.1 5.6e-52 175.9 0.1 1.1 1 0 0 1 1 1 1 Putative FMN-binding domain Laminin_G_3 PF13385.6 KXS12361.1 - 0.023 14.8 0.4 0.037 14.2 0.4 1.5 1 0 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily CTK3_C PF12350.8 KXS12362.1 - 2.2e-08 34.1 0.8 4.8e-08 33.1 0.8 1.5 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 C-terminus CTK3 PF12243.8 KXS12362.1 - 2.4e-05 24.3 0.0 4e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTD_bind PF04818.13 KXS12362.1 - 0.0039 18.0 0.1 0.014 16.2 0.1 2.0 2 0 0 2 2 2 1 RNA polymerase II-binding domain. TF_Zn_Ribbon PF08271.12 KXS12363.1 - 0.029 13.9 0.2 0.058 12.9 0.2 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding DnaJ PF00226.31 KXS12364.1 - 2.3e-12 46.8 1.2 2.8e-12 46.6 1.2 1.1 1 0 0 1 1 1 1 DnaJ domain CorA PF01544.18 KXS12365.1 - 5e-36 124.5 1.4 2.2e-30 106.0 0.6 2.2 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein Pox_A11 PF05061.13 KXS12365.1 - 0.028 13.7 0.0 2.1 7.6 0.0 2.2 2 0 0 2 2 2 0 Poxvirus A11 Protein Dus PF01207.17 KXS12366.1 - 1.4e-78 264.2 0.0 1.6e-78 264.0 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) NMO PF03060.15 KXS12366.1 - 1.4e-05 24.6 0.0 2.1e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase SOR_SNZ PF01680.17 KXS12366.1 - 0.00019 21.3 1.2 0.016 15.0 0.1 2.2 1 1 1 2 2 2 2 SOR/SNZ family DHO_dh PF01180.21 KXS12366.1 - 0.00023 20.5 0.0 0.03 13.5 0.0 2.1 2 0 0 2 2 2 2 Dihydroorotate dehydrogenase G3P_antiterm PF04309.12 KXS12366.1 - 0.0014 18.1 0.0 0.0024 17.3 0.0 1.4 1 0 0 1 1 1 1 Glycerol-3-phosphate responsive antiterminator His_biosynth PF00977.21 KXS12366.1 - 0.0023 17.5 0.1 0.011 15.3 0.1 1.9 1 1 0 1 1 1 1 Histidine biosynthesis protein IMPDH PF00478.25 KXS12366.1 - 0.0096 15.0 0.0 0.019 14.0 0.0 1.4 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.14 KXS12366.1 - 0.013 14.8 0.0 0.026 13.9 0.0 1.4 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG FMN_dh PF01070.18 KXS12366.1 - 0.083 11.9 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 FMN-dependent dehydrogenase LRR_6 PF13516.6 KXS12367.1 - 5.8e-07 29.1 0.6 0.2 11.8 0.0 5.4 6 0 0 6 6 6 2 Leucine Rich repeat Senescence_reg PF04520.13 KXS12367.1 - 0.28 12.0 8.0 0.5 11.2 8.0 1.4 1 0 0 1 1 1 0 Senescence regulator LRR_1 PF00560.33 KXS12367.1 - 0.61 10.9 4.9 2.9 8.8 0.1 3.7 3 0 0 3 3 3 0 Leucine Rich Repeat Presenilin PF01080.17 KXS12367.1 - 1 8.1 7.1 1.3 7.7 7.1 1.1 1 0 0 1 1 1 0 Presenilin LZ_Tnp_IS66 PF13007.7 KXS12367.1 - 2.8 8.8 7.1 0.25 12.2 0.8 2.5 2 2 0 2 2 2 0 Transposase C of IS166 homeodomain DTHCT PF08070.11 KXS12367.1 - 3.1 8.6 20.6 4 8.2 14.7 2.5 2 0 0 2 2 2 0 DTHCT (NUC029) region E7 PF00527.18 KXS12367.1 - 3.5 7.9 5.3 1.1 9.5 0.4 2.9 2 1 1 3 3 3 0 E7 protein, Early protein SRP-alpha_N PF04086.13 KXS12367.1 - 9 6.1 16.5 1.4 8.8 12.2 1.7 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal SNF2_N PF00176.23 KXS12368.1 - 4.3e-45 154.0 0.1 1.6e-33 115.9 0.0 3.1 3 0 0 3 3 3 2 SNF2 family N-terminal domain Helicase_C PF00271.31 KXS12368.1 - 2e-10 41.0 0.1 2.8e-09 37.3 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.25 KXS12368.1 - 1.7e-06 27.8 5.2 1.7e-06 27.8 5.2 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KXS12368.1 - 3.3e-06 26.8 3.1 3.3e-06 26.8 3.1 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXS12368.1 - 6.9e-05 22.7 3.7 6.9e-05 22.7 3.7 2.2 2 0 0 2 2 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KXS12368.1 - 7.1e-05 22.7 1.6 0.00019 21.4 0.4 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KXS12368.1 - 0.0002 21.2 3.7 0.0002 21.2 3.7 2.9 2 1 1 3 3 1 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.29 KXS12368.1 - 0.00024 20.9 0.0 0.0005 19.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_2 PF13639.6 KXS12368.1 - 0.00071 19.9 4.0 0.00071 19.9 4.0 2.4 2 0 0 2 2 2 1 Ring finger domain zf-Nse PF11789.8 KXS12368.1 - 0.0059 16.4 2.0 0.013 15.3 2.0 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.6 KXS12368.1 - 0.0082 16.0 3.6 0.0082 16.0 3.6 2.0 2 0 0 2 2 1 1 Prokaryotic RING finger family 4 ResIII PF04851.15 KXS12368.1 - 0.009 16.0 0.0 0.24 11.4 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Uds1 PF15456.6 KXS12368.1 - 0.055 13.6 1.1 1.5 9.0 0.4 2.8 2 0 0 2 2 2 0 Up-regulated During Septation DPBB_1 PF03330.18 KXS12369.1 - 0.057 13.7 0.0 0.072 13.4 0.0 1.2 1 0 0 1 1 1 0 Lytic transglycolase DPBB_1 PF03330.18 KXS12371.1 - 0.056 13.7 0.0 0.069 13.4 0.0 1.2 1 0 0 1 1 1 0 Lytic transglycolase PHP PF02811.19 KXS12373.1 - 7.2e-15 55.7 0.1 1.2e-14 55.0 0.1 1.4 1 0 0 1 1 1 1 PHP domain UQ_con PF00179.26 KXS12375.1 - 1e-46 158.1 0.0 1.2e-46 157.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Pcc1 PF09341.10 KXS12376.1 - 8e-19 67.6 0.0 9.2e-19 67.4 0.0 1.0 1 0 0 1 1 1 1 Transcription factor Pcc1 DUF3128 PF11326.8 KXS12377.1 - 1.8e-19 69.9 2.3 2.2e-19 69.6 2.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) SPATA3 PF15662.5 KXS12377.1 - 0.028 15.1 0.1 0.039 14.6 0.1 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated protein 3 family COPIIcoated_ERV PF07970.12 KXS12378.1 - 4.9e-37 127.9 0.0 8e-37 127.2 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 KXS12378.1 - 4.3e-21 75.1 0.0 6.8e-21 74.4 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Myosin_head PF00063.21 KXS12380.1 - 6e-223 741.9 0.0 8.9e-172 572.8 0.2 2.3 2 0 0 2 2 2 2 Myosin head (motor domain) IQ PF00612.27 KXS12380.1 - 1.3e-17 61.9 34.0 9.4e-06 25.0 0.6 6.7 6 0 0 6 6 6 5 IQ calmodulin-binding motif DIL PF01843.19 KXS12380.1 - 2.6e-17 63.0 0.1 1e-16 61.1 0.1 2.1 1 0 0 1 1 1 1 DIL domain AAA_22 PF13401.6 KXS12380.1 - 0.023 15.0 0.0 0.098 12.9 0.0 2.1 1 0 0 1 1 1 0 AAA domain Myosin_N PF02736.19 KXS12380.1 - 0.029 14.2 0.4 0.094 12.6 0.4 1.9 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain DUF812 PF05667.11 KXS12380.1 - 0.098 11.5 20.1 0.15 10.9 20.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) CENP-F_leu_zip PF10473.9 KXS12380.1 - 0.15 12.1 14.2 0.16 12.0 13.0 1.8 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 RsgA_GTPase PF03193.16 KXS12380.1 - 0.16 11.8 0.6 0.75 9.7 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase Fib_alpha PF08702.10 KXS12380.1 - 0.54 10.4 10.8 0.034 14.3 2.4 3.0 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family SHE3 PF17078.5 KXS12380.1 - 0.82 9.3 14.5 0.029 14.1 6.0 2.3 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 DUF724 PF05266.14 KXS12380.1 - 1.4 8.7 15.3 0.54 10.1 2.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF724) FAM76 PF16046.5 KXS12380.1 - 2.2 7.6 14.4 4.1 6.7 14.4 1.4 1 0 0 1 1 1 0 FAM76 protein TMPIT PF07851.13 KXS12380.1 - 2.3 7.4 11.6 0.066 12.5 1.3 2.3 1 1 1 2 2 2 0 TMPIT-like protein FlxA PF14282.6 KXS12380.1 - 3.3 7.7 11.7 3.9 7.5 0.8 3.0 2 1 1 3 3 3 0 FlxA-like protein PGM_PMM_I PF02878.16 KXS12381.1 - 3.3e-35 120.8 0.1 5e-35 120.2 0.1 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 KXS12381.1 - 2.8e-27 95.1 0.0 6.1e-27 94.1 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 KXS12381.1 - 6.7e-16 58.8 0.0 1.8e-15 57.4 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 KXS12381.1 - 2e-08 34.3 0.0 4.8e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain WW PF00397.26 KXS12382.1 - 7.9e-13 48.3 1.5 1.2e-12 47.7 1.5 1.3 1 0 0 1 1 1 1 WW domain DUF2076 PF09849.9 KXS12382.1 - 0.0041 17.2 1.7 0.0044 17.1 1.7 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) Chorion_3 PF05387.11 KXS12382.1 - 8.4 5.9 16.1 4.5 6.8 14.7 1.3 1 1 0 1 1 1 0 Chorion family 3 MMgT PF10270.9 KXS12383.1 - 3.1e-13 49.9 0.0 4.2e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 Membrane magnesium transporter F-box-like PF12937.7 KXS12384.1 - 0.00012 21.9 0.0 0.00025 20.9 0.0 1.5 1 0 0 1 1 1 1 F-box-like Proteasome PF00227.26 KXS12385.1 - 5e-38 130.5 0.0 6e-38 130.2 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome PF00227.26 KXS12386.1 - 6.1e-47 159.6 0.5 7.1e-47 159.4 0.5 1.1 1 0 0 1 1 1 1 Proteasome subunit Cerato-platanin PF07249.12 KXS12387.1 - 1.6e-06 28.2 0.1 1.8e-06 28.1 0.1 1.1 1 0 0 1 1 1 1 Cerato-platanin DPBB_1 PF03330.18 KXS12387.1 - 0.0018 18.5 0.2 0.0032 17.7 0.2 1.5 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 KXS12387.1 - 0.0018 18.1 0.0 0.002 18.0 0.0 1.1 1 0 0 1 1 1 1 Barwin family DUF2690 PF10901.8 KXS12387.1 - 0.11 12.8 0.1 0.14 12.5 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2690) TFIIB PF00382.19 KXS12388.1 - 0.00041 20.3 0.0 0.0064 16.5 0.0 2.2 2 0 0 2 2 2 1 Transcription factor TFIIB repeat Response_reg PF00072.24 KXS12389.1 - 1.3e-07 31.8 0.0 3.8e-07 30.3 0.0 1.7 1 1 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 KXS12389.1 - 4.4e-05 23.9 0.0 8.7e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase RNA_pol_Rpb1_R PF05001.13 KXS12389.1 - 0.41 11.1 6.9 3.1 8.3 6.9 2.3 1 1 0 1 1 1 0 RNA polymerase Rpb1 C-terminal repeat GATase PF00117.28 KXS12390.1 - 2.7e-13 50.1 0.0 4.1e-13 49.5 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KXS12390.1 - 0.0042 16.9 0.8 0.15 11.8 0.1 2.8 1 1 1 2 2 2 1 Peptidase C26 FAD_binding_3 PF01494.19 KXS12391.1 - 4.3e-17 62.4 0.1 1.6e-16 60.5 0.1 1.9 1 1 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 KXS12391.1 - 6.7e-05 22.1 1.9 0.00012 21.3 1.9 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KXS12391.1 - 7e-05 23.0 0.6 0.00017 21.7 0.6 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KXS12391.1 - 0.0014 18.1 1.5 0.0021 17.5 1.5 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXS12391.1 - 0.0069 15.7 2.8 0.013 14.7 0.4 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KXS12391.1 - 0.031 13.3 1.4 0.051 12.7 1.4 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KXS12391.1 - 0.061 12.6 1.1 0.1 11.9 1.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXS12391.1 - 0.23 11.0 3.7 0.43 10.1 3.7 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Cerato-platanin PF07249.12 KXS12394.1 - 2.3e-14 53.5 1.3 2.3e-14 53.5 1.3 2.0 2 0 0 2 2 2 1 Cerato-platanin Barwin PF00967.17 KXS12394.1 - 0.00017 21.4 0.9 0.00017 21.4 0.9 2.0 2 1 0 2 2 2 1 Barwin family ETRAMP PF09716.10 KXS12394.1 - 0.09 12.9 0.1 0.16 12.0 0.1 1.4 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Gaa1 PF04114.14 KXS12395.1 - 2.1e-59 201.9 1.7 1.1e-58 199.5 1.7 1.8 1 1 0 1 1 1 1 Gaa1-like, GPI transamidase component Dynactin_p62 PF05502.13 KXS12396.1 - 8.3e-50 169.9 13.6 2.1e-33 115.8 6.3 2.3 1 1 1 2 2 2 2 Dynactin p62 family AMPK1_CBM PF16561.5 KXS12397.1 - 5.1e-34 116.4 0.0 9.3e-34 115.5 0.0 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase AMPKBI PF04739.15 KXS12397.1 - 7.3e-24 83.8 3.1 1.7e-23 82.7 3.1 1.7 1 0 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interaction domain CBM53 PF16760.5 KXS12397.1 - 0.01 16.4 0.0 0.029 14.9 0.0 1.7 1 0 0 1 1 1 0 Starch/carbohydrate-binding module (family 53) SR-25 PF10500.9 KXS12397.1 - 1.1 8.8 7.5 2.3 7.7 7.5 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Cytochrom_B558a PF05038.13 KXS12397.1 - 6.5 6.3 6.7 27 4.3 4.9 2.6 2 0 0 2 2 2 0 Cytochrome Cytochrome b558 alpha-subunit Suc_Fer-like PF06999.12 KXS12398.1 - 9e-27 94.2 0.0 1.5e-26 93.4 0.0 1.3 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Fer2 PF00111.27 KXS12398.1 - 5.8e-10 39.0 0.4 1.3e-09 37.9 0.4 1.6 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Abhydrolase_3 PF07859.13 KXS12400.1 - 2.3e-34 119.1 0.0 1.6e-27 96.7 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KXS12400.1 - 1.7e-05 23.9 0.0 0.00027 19.9 0.0 2.0 2 0 0 2 2 2 2 Steryl acetyl hydrolase Lactamase_B PF00753.27 KXS12401.1 - 9.8e-19 68.1 1.2 1.5e-18 67.5 1.2 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily BLACT_WH PF17778.1 KXS12401.1 - 1.4e-14 53.8 0.4 3.6e-14 52.5 0.4 1.8 1 0 0 1 1 1 1 Beta-lactamase associated winged helix domain Lactamase_B_2 PF12706.7 KXS12401.1 - 3.6e-07 29.9 0.0 5.7e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KXS12401.1 - 0.034 14.0 0.0 0.13 12.2 0.0 1.8 2 0 0 2 2 2 0 Beta-lactamase superfamily domain PEX11 PF05648.14 KXS12402.1 - 2.8e-13 49.8 0.1 1.3e-09 37.8 0.0 2.1 2 0 0 2 2 2 2 Peroxisomal biogenesis factor 11 (PEX11) Exo70 PF03081.15 KXS12403.1 - 8.7e-77 258.7 0.0 2.5e-76 257.2 0.0 1.7 2 0 0 2 2 2 1 Exo70 exocyst complex subunit COG6 PF06419.11 KXS12403.1 - 0.0026 16.1 2.2 0.17 10.0 0.2 2.8 2 2 1 3 3 3 2 Conserved oligomeric complex COG6 APG17 PF04108.12 KXS12403.1 - 0.019 14.1 0.7 0.086 11.9 0.6 2.1 2 0 0 2 2 2 0 Autophagy protein Apg17 Vps52 PF04129.12 KXS12403.1 - 0.077 11.7 1.8 1.9 7.1 0.5 2.5 2 0 0 2 2 2 0 Vps52 / Sac2 family KLRAQ PF10205.9 KXS12403.1 - 0.12 12.6 0.2 0.33 11.2 0.2 1.7 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein Baculo_PEP_C PF04513.12 KXS12403.1 - 0.22 11.6 2.8 14 5.7 0.6 2.6 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus YTH PF04146.15 KXS12404.1 - 5.2e-11 42.8 0.1 1.4e-10 41.4 0.1 1.6 2 0 0 2 2 2 1 YT521-B-like domain RRM_1 PF00076.22 KXS12404.1 - 2.3e-06 27.3 0.0 3.7e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1725 PF08333.11 KXS12405.1 - 0.14 11.8 0.2 0.25 11.0 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1725) 6PF2K PF01591.18 KXS12406.1 - 1.2e-70 237.3 0.1 1.9e-70 236.7 0.1 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 KXS12406.1 - 1.8e-35 122.4 0.0 2.2e-34 118.9 0.0 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 KXS12406.1 - 8.1e-05 22.8 0.0 0.00017 21.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF2313 PF10076.9 KXS12406.1 - 0.036 13.9 0.0 0.059 13.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2313) KTI12 PF08433.10 KXS12406.1 - 0.13 11.7 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 FAD_binding_3 PF01494.19 KXS12407.1 - 5e-25 88.5 0.0 3.2e-24 85.8 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KXS12407.1 - 3.4e-09 36.4 0.0 0.00057 19.2 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXS12407.1 - 5.3e-07 29.2 0.2 0.023 14.0 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXS12407.1 - 6.1e-07 28.5 0.3 0.013 14.2 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein DAO PF01266.24 KXS12407.1 - 2.8e-06 27.2 0.1 0.065 12.8 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 KXS12407.1 - 1.1e-05 25.9 0.4 0.036 14.6 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 KXS12407.1 - 0.00021 20.4 0.0 0.42 9.6 0.0 2.1 2 0 0 2 2 2 2 Squalene epoxidase NAD_binding_8 PF13450.6 KXS12407.1 - 0.0011 19.2 0.0 0.0025 18.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 KXS12407.1 - 0.0011 17.9 0.7 0.26 10.1 0.0 2.1 2 0 0 2 2 2 2 Tryptophan halogenase NAD_binding_9 PF13454.6 KXS12407.1 - 0.021 14.8 1.0 0.28 11.2 0.1 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 KXS12407.1 - 0.024 13.8 0.0 0.062 12.4 0.0 1.7 2 0 0 2 2 2 0 FAD binding domain Amino_oxidase PF01593.24 KXS12407.1 - 0.033 13.5 0.0 0.077 12.3 0.0 1.6 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Oxidored_FMN PF00724.20 KXS12408.1 - 5e-23 81.9 0.0 5e-18 65.5 0.0 2.1 1 1 1 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family PRCC PF10253.9 KXS12411.1 - 1.1 10.0 4.5 2.3 9.0 4.5 1.5 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting GARP PF16731.5 KXS12412.1 - 0.0066 16.2 0.1 0.0069 16.1 0.1 1.0 1 0 0 1 1 1 1 Glutamic acid/alanine-rich protein of Trypanosoma LAMTOR PF15454.6 KXS12412.1 - 0.1 13.2 0.0 0.12 13.0 0.0 1.2 1 0 0 1 1 1 0 Late endosomal/lysosomal adaptor and MAPK and MTOR activator DegS PF05384.11 KXS12412.1 - 0.14 11.7 0.0 0.15 11.6 0.0 1.0 1 0 0 1 1 1 0 Sensor protein DegS F-box-like PF12937.7 KXS12414.1 - 0.013 15.4 0.1 0.023 14.6 0.1 1.4 1 0 0 1 1 1 0 F-box-like F-box PF00646.33 KXS12414.1 - 0.12 12.3 0.1 0.3 11.0 0.1 1.7 1 0 0 1 1 1 0 F-box domain HlyIII PF03006.20 KXS12415.1 - 1.6e-54 185.0 22.3 1.9e-54 184.7 22.3 1.1 1 0 0 1 1 1 1 Haemolysin-III related TMEM238 PF15125.6 KXS12415.1 - 0.18 12.0 0.3 0.18 12.0 0.3 3.3 1 1 2 3 3 3 0 TMEM238 protein family Fungal_trans_2 PF11951.8 KXS12420.1 - 0.038 12.8 0.0 0.049 12.4 0.0 1.1 1 0 0 1 1 1 0 Fungal specific transcription factor domain OmpH PF03938.14 KXS12422.1 - 2.7e-05 24.5 18.1 0.0095 16.3 10.9 2.3 2 0 0 2 2 2 2 Outer membrane protein (OmpH-like) Nup54 PF13874.6 KXS12422.1 - 5.9e-05 23.2 2.0 0.00048 20.2 2.0 2.1 1 1 0 1 1 1 1 Nucleoporin complex subunit 54 Flg_hook PF02120.16 KXS12422.1 - 0.00021 21.1 9.7 0.00083 19.2 0.5 3.1 3 0 0 3 3 3 1 Flagellar hook-length control protein FliK DUF4407 PF14362.6 KXS12422.1 - 0.0018 17.7 6.0 0.0027 17.1 6.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) Bactofilin PF04519.13 KXS12422.1 - 0.014 15.7 0.4 0.35 11.2 0.0 2.8 2 1 0 2 2 2 0 Polymer-forming cytoskeletal DUF2218 PF09981.9 KXS12422.1 - 0.016 15.6 1.8 5.9 7.4 0.0 3.1 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2218) Spore_GerAC PF05504.11 KXS12422.1 - 0.02 15.1 0.9 0.02 15.1 0.9 2.0 2 0 0 2 2 2 0 Spore germination B3/ GerAC like, C-terminal CHIP_TPR_N PF18391.1 KXS12422.1 - 0.025 15.4 3.8 0.025 15.4 3.8 2.4 1 1 1 2 2 2 0 CHIP N-terminal tetratricopeptide repeat domain Luteo_P1-P2 PF08467.10 KXS12422.1 - 0.027 13.8 6.1 0.07 12.4 6.0 1.6 1 1 1 2 2 2 0 Luteovirus RNA polymerase P1-P2/replicase Baculo_PEP_C PF04513.12 KXS12422.1 - 0.029 14.4 7.0 0.48 10.4 4.0 2.4 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Apolipoprotein PF01442.18 KXS12422.1 - 0.048 13.5 18.8 0.54 10.1 18.8 2.5 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF45 PF01863.17 KXS12422.1 - 0.077 13.0 1.1 0.2 11.7 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function DUF45 CCDC-167 PF15188.6 KXS12422.1 - 0.29 11.5 0.1 0.29 11.5 0.1 3.0 2 1 1 3 3 3 0 Coiled-coil domain-containing protein 167 Med9 PF07544.13 KXS12422.1 - 0.35 11.0 15.7 1.6 8.9 3.3 3.3 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 HlyD_2 PF12700.7 KXS12422.1 - 0.42 9.3 9.6 1.4 7.6 3.1 2.1 2 0 0 2 2 2 0 HlyD family secretion protein FliT PF05400.13 KXS12422.1 - 1.3 9.9 16.9 0.27 12.1 0.5 3.1 2 1 0 2 2 2 0 Flagellar protein FliT Cauli_DNA-bind PF03310.13 KXS12422.1 - 1.4 9.0 5.6 6.6 6.8 1.7 2.2 2 0 0 2 2 2 0 Caulimovirus DNA-binding protein Mitofilin PF09731.9 KXS12422.1 - 2.4 6.9 17.5 3.5 6.3 10.9 2.0 2 0 0 2 2 2 0 Mitochondrial inner membrane protein Fib_alpha PF08702.10 KXS12422.1 - 2.5 8.3 9.7 16 5.7 2.3 3.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Phage_Mu_Gam PF07352.12 KXS12422.1 - 3.8 7.4 20.6 0.88 9.5 0.9 3.0 2 1 1 3 3 3 0 Bacteriophage Mu Gam like protein DUF5403 PF17395.2 KXS12422.1 - 4.6 7.6 7.6 37 4.7 0.8 3.1 2 1 1 3 3 3 0 Family of unknown function (DUF5403) DUF5595 PF18077.1 KXS12422.1 - 8 6.6 7.9 14 5.9 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF5595) DUF1690 PF07956.11 KXS12422.1 - 8.9 6.7 11.5 13 6.2 5.5 2.2 2 0 0 2 2 2 0 Protein of Unknown function (DUF1690) Nt_Gln_amidase PF09764.9 KXS12423.1 - 4.9e-59 199.0 0.0 5.7e-59 198.8 0.0 1.0 1 0 0 1 1 1 1 N-terminal glutamine amidase DUF676 PF05057.14 KXS12424.1 - 5e-05 22.9 0.0 0.00013 21.6 0.0 1.7 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Annexin PF00191.20 KXS12425.1 - 9.7e-32 108.9 0.1 7.6e-12 45.1 0.1 4.2 4 0 0 4 4 4 4 Annexin DUF2255 PF10012.9 KXS12425.1 - 0.13 12.4 0.1 20 5.4 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2255) AOC_like PF18678.1 KXS12425.1 - 0.15 11.7 0.0 0.41 10.3 0.0 1.7 2 0 0 2 2 2 0 Allene oxide cyclase barrel like domain Longin PF13774.6 KXS12426.1 - 4.5e-29 100.3 0.1 7.8e-29 99.6 0.1 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 KXS12426.1 - 1.5e-16 60.0 0.1 2.1e-16 59.5 0.1 1.3 1 0 0 1 1 1 1 Synaptobrevin T2SSF PF00482.23 KXS12426.1 - 0.14 12.1 0.1 1.4 8.8 0.0 2.1 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F UPF0767 PF15990.5 KXS12426.1 - 0.15 12.2 0.1 0.34 11.1 0.1 1.6 1 0 0 1 1 1 0 UPF0767 family MFS_1 PF07690.16 KXS12427.1 - 3.7e-22 78.7 24.2 3e-14 52.7 7.4 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Oxidored_q5_N PF01059.17 KXS12427.1 - 0.69 10.0 6.1 3.2 7.9 1.2 2.9 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase chain 4, amino terminus zf-MYND PF01753.18 KXS12428.1 - 4.2e-09 36.3 6.8 1e-08 35.1 6.8 1.7 1 0 0 1 1 1 1 MYND finger DUF1664 PF07889.12 KXS12429.1 - 0.055 13.5 3.7 16 5.5 0.0 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF2884 PF11101.8 KXS12429.1 - 0.34 10.4 3.3 2 7.9 0.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2884) Apolipoprotein PF01442.18 KXS12429.1 - 0.57 10.0 14.0 17 5.2 13.5 2.7 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain HSCB_C PF07743.13 KXS12429.1 - 0.64 10.6 3.7 49 4.5 1.4 3.7 2 2 1 3 3 3 0 HSCB C-terminal oligomerisation domain ApoLp-III PF07464.11 KXS12429.1 - 0.73 9.9 4.1 5.8 7.0 0.5 2.9 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) zf-C3HC4 PF00097.25 KXS12430.1 - 1.7e-06 27.8 1.7 2.9e-06 27.0 1.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KXS12430.1 - 2.3e-06 27.3 1.1 3.8e-06 26.6 1.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXS12430.1 - 0.00036 20.3 3.5 0.00068 19.4 3.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXS12430.1 - 0.0039 17.5 2.4 0.0068 16.7 2.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KXS12430.1 - 0.0056 16.7 1.1 0.011 15.8 1.1 1.5 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KXS12430.1 - 0.012 15.4 2.1 0.021 14.7 2.1 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KXS12430.1 - 0.014 15.3 1.5 0.023 14.6 1.5 1.3 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KXS12430.1 - 0.33 11.1 1.5 0.65 10.2 1.5 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING LRR_8 PF13855.6 KXS12431.1 - 0.043 13.6 0.7 7.2 6.5 0.7 2.6 2 0 0 2 2 2 0 Leucine rich repeat LRR_4 PF12799.7 KXS12431.1 - 0.16 12.4 3.2 5.9 7.5 1.0 3.0 2 1 0 2 2 2 0 Leucine Rich repeats (2 copies) tRNA-synt_1g PF09334.11 KXS12432.1 - 2.2e-99 332.9 0.0 8e-99 331.0 0.0 1.7 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 KXS12432.1 - 4e-28 98.0 0.3 5.5e-12 44.7 0.2 3.1 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 KXS12432.1 - 5.1e-11 42.5 0.0 5.1e-05 22.8 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 KXS12432.1 - 0.13 11.1 0.0 0.22 10.4 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (K) Lectin_leg-like PF03388.13 KXS12435.1 - 3.1e-47 160.8 0.0 4.4e-47 160.4 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family Bact_lectin PF18483.1 KXS12435.1 - 0.00053 20.1 0.0 0.00079 19.5 0.0 1.2 1 0 0 1 1 1 1 Bacterial lectin DUF16 PF01519.16 KXS12435.1 - 0.78 10.3 8.4 3.4 8.2 0.3 2.7 2 1 0 2 2 2 0 Protein of unknown function DUF16 Oxidored_FMN PF00724.20 KXS12436.1 - 3.2e-47 161.5 0.0 3.9e-47 161.2 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family TMEM135_C_rich PF15982.5 KXS12437.1 - 6.9e-08 33.2 1.1 1e-06 29.4 0.3 2.3 2 0 0 2 2 2 1 N-terminal cysteine-rich region of Transmembrane protein 135 DUF4149 PF13664.6 KXS12437.1 - 0.33 11.3 2.8 0.5 10.7 0.8 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4149) AIRC PF00731.20 KXS12438.1 - 5.7e-61 204.4 2.1 5.7e-61 204.4 2.1 2.3 3 0 0 3 3 3 1 AIR carboxylase ATP-grasp PF02222.22 KXS12438.1 - 3.3e-54 183.0 0.0 6.4e-54 182.1 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain PurK_C PF17769.1 KXS12438.1 - 1.2e-18 66.5 0.1 2.3e-18 65.6 0.1 1.5 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain CPSase_L_D2 PF02786.17 KXS12438.1 - 4.8e-05 22.9 0.0 8.5e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Dala_Dala_lig_C PF07478.13 KXS12438.1 - 0.0013 18.3 0.0 0.0042 16.7 0.0 1.8 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus AlaDh_PNT_C PF01262.21 KXS12438.1 - 0.0016 17.8 0.1 0.0039 16.5 0.1 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ATP-grasp_5 PF13549.6 KXS12438.1 - 0.0019 17.7 0.0 0.0039 16.7 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain 2-Hacid_dh_C PF02826.19 KXS12438.1 - 0.0024 17.2 0.0 0.0047 16.3 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain SnoaL_4 PF13577.6 KXS12439.1 - 0.00063 19.9 1.8 0.00068 19.8 1.8 1.1 1 0 0 1 1 1 1 SnoaL-like domain DUF1799 PF08809.11 KXS12439.1 - 0.046 13.9 0.4 0.055 13.7 0.4 1.2 1 0 0 1 1 1 0 Phage related hypothetical protein (DUF1799) AA_permease_2 PF13520.6 KXS12440.1 - 5.8e-51 173.7 48.8 6.9e-51 173.4 48.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXS12440.1 - 4.6e-23 81.6 40.1 6.8e-23 81.0 40.1 1.2 1 0 0 1 1 1 1 Amino acid permease Alpha_L_fucos PF01120.17 KXS12441.1 - 1.7e-48 165.9 0.4 2.3e-48 165.4 0.4 1.1 1 0 0 1 1 1 1 Alpha-L-fucosidase CoA_transf_3 PF02515.17 KXS12442.1 - 4.7e-127 424.1 0.0 5.3e-127 423.9 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III FTHFS PF01268.19 KXS12444.1 - 3.7e-261 867.2 0.2 1.1e-260 865.6 0.0 1.7 2 0 0 2 2 2 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 KXS12444.1 - 3.5e-63 211.7 2.3 8.5e-63 210.4 2.3 1.7 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 KXS12444.1 - 3.5e-39 133.7 1.0 6.8e-39 132.7 1.0 1.5 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain TACC_C PF05010.14 KXS12445.1 - 2.4e-16 60.1 34.1 2.4e-16 60.1 34.1 1.9 2 0 0 2 2 2 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Cadherin_C PF01049.17 KXS12445.1 - 0.2 12.0 1.7 0.3 11.4 0.0 2.1 2 0 0 2 2 2 0 Cadherin cytoplasmic region 3Beta_HSD PF01073.19 KXS12447.1 - 6.3e-23 81.2 0.0 5.4e-19 68.3 0.0 2.1 1 1 1 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KXS12447.1 - 0.0017 17.9 0.0 0.079 12.4 0.0 2.1 1 1 1 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KXS12447.1 - 0.052 12.7 0.0 0.091 11.9 0.0 1.4 1 0 0 1 1 1 0 Male sterility protein TPR_19 PF14559.6 KXS12448.1 - 3.9e-32 110.6 22.6 5.8e-06 26.7 2.1 9.7 6 3 3 10 10 10 7 Tetratricopeptide repeat TPR_16 PF13432.6 KXS12448.1 - 3.7e-28 97.9 55.8 1.2e-06 29.1 5.1 11.3 11 1 1 12 12 11 6 Tetratricopeptide repeat TPR_2 PF07719.17 KXS12448.1 - 2e-27 93.0 33.4 0.002 18.1 0.0 15.0 16 0 0 16 16 14 5 Tetratricopeptide repeat TPR_14 PF13428.6 KXS12448.1 - 7.4e-22 76.2 50.6 0.0039 17.9 4.5 13.9 9 6 6 15 15 14 6 Tetratricopeptide repeat TPR_12 PF13424.6 KXS12448.1 - 1.2e-20 73.6 28.9 0.00015 22.0 0.0 10.5 8 2 2 10 10 10 5 Tetratricopeptide repeat TPR_1 PF00515.28 KXS12448.1 - 1.3e-20 72.2 12.4 0.0044 16.8 0.0 12.2 13 0 0 13 13 13 4 Tetratricopeptide repeat TPR_6 PF13174.6 KXS12448.1 - 9.1e-19 66.8 16.8 0.057 14.1 0.1 12.1 13 0 0 13 13 12 5 Tetratricopeptide repeat TPR_8 PF13181.6 KXS12448.1 - 3.3e-15 55.0 8.8 0.79 10.1 0.0 11.4 11 0 0 11 11 11 4 Tetratricopeptide repeat TPR_17 PF13431.6 KXS12448.1 - 6.2e-14 51.3 7.3 0.53 10.8 0.1 11.5 13 0 0 13 13 13 2 Tetratricopeptide repeat TPR_7 PF13176.6 KXS12448.1 - 4.4e-12 45.1 6.1 1.2 9.4 0.3 11.3 12 1 0 12 12 11 1 Tetratricopeptide repeat TPR_11 PF13414.6 KXS12448.1 - 1.2e-11 44.1 1.5 1.6 8.5 0.0 8.7 7 2 2 9 9 9 2 TPR repeat ANAPC3 PF12895.7 KXS12448.1 - 1.7e-09 37.8 1.7 0.0054 16.9 0.0 6.0 7 0 0 7 7 7 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 KXS12448.1 - 1.1e-07 31.9 27.0 0.056 13.6 3.3 8.7 7 3 3 10 10 10 3 Tetratricopeptide repeat TPR_10 PF13374.6 KXS12448.1 - 2.5e-05 24.0 22.1 0.38 10.7 0.5 9.3 10 0 0 10 10 10 3 Tetratricopeptide repeat GGDEF PF00990.21 KXS12448.1 - 0.0048 16.7 0.0 0.26 11.0 0.0 2.7 2 0 0 2 2 2 1 Diguanylate cyclase, GGDEF domain TPR_5 PF12688.7 KXS12448.1 - 0.044 14.0 3.9 0.13 12.5 0.3 3.7 3 1 1 4 4 4 0 Tetratrico peptide repeat HrpB1_HrpK PF09613.10 KXS12448.1 - 0.055 13.1 10.4 0.065 12.9 0.0 4.2 4 1 1 5 5 5 0 Bacterial type III secretion protein (HrpB1_HrpK) p450 PF00067.22 KXS12449.1 - 1.4e-30 106.5 0.0 1.8e-30 106.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 HTH_32 PF13565.6 KXS12449.1 - 0.14 12.7 0.0 0.31 11.7 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain CDP-OH_P_transf PF01066.21 KXS12450.1 - 4.1e-12 46.7 0.5 1e-11 45.4 0.5 1.7 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase Nckap1 PF09735.9 KXS12451.1 - 1.2e-41 142.8 0.0 1.3e-28 99.6 0.0 3.9 2 1 0 2 2 2 2 Membrane-associated apoptosis protein Phosducin PF02114.16 KXS12452.1 - 4.2e-17 62.0 0.1 7.1e-17 61.2 0.1 1.3 1 1 0 1 1 1 1 Phosducin PYC_OADA PF02436.18 KXS12452.1 - 0.021 14.6 0.4 0.033 13.9 0.4 1.3 1 0 0 1 1 1 0 Conserved carboxylase domain DUF4515 PF14988.6 KXS12454.1 - 1.3e-12 48.0 33.4 1.3e-12 48.0 33.4 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4515) DUF4618 PF15397.6 KXS12454.1 - 2.2e-09 37.2 29.9 3.1e-09 36.6 29.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4618) Spc7 PF08317.11 KXS12454.1 - 0.0012 17.8 35.7 0.023 13.6 22.3 2.5 1 1 0 2 2 2 2 Spc7 kinetochore protein FAM184 PF15665.5 KXS12454.1 - 0.0066 16.3 23.9 0.0066 16.3 23.9 2.2 1 1 1 2 2 2 2 Family with sequence similarity 184, A and B APC_N_CC PF16689.5 KXS12454.1 - 0.11 12.5 8.7 4.4 7.4 0.1 4.0 3 1 1 4 4 4 0 Coiled-coil N-terminus of APC, dimerisation domain TSC22 PF01166.18 KXS12454.1 - 0.14 12.5 17.8 0.13 12.5 0.8 5.1 3 2 2 5 5 5 0 TSC-22/dip/bun family DUF1664 PF07889.12 KXS12454.1 - 1.2 9.2 18.0 2.7 8.0 6.5 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) ComP_DUS PF16732.5 KXS12454.1 - 1.9 9.4 5.4 3.2 8.7 0.1 3.3 2 2 1 3 3 3 0 Type IV minor pilin ComP, DNA uptake sequence receptor Hemagglutinin PF00509.18 KXS12454.1 - 2 6.7 6.6 2.8 6.3 6.6 1.2 1 0 0 1 1 1 0 Haemagglutinin MIT_C PF16565.5 KXS12454.1 - 4.5 7.3 8.2 2.7 8.0 3.2 2.6 1 1 2 3 3 3 0 Phospholipase D-like domain at C-terminus of MIT TFIIE_alpha PF02002.17 KXS12455.1 - 3.6e-13 49.3 1.1 7.2e-13 48.3 1.1 1.5 1 0 0 1 1 1 1 TFIIE alpha subunit TF_Zn_Ribbon PF08271.12 KXS12455.1 - 0.00081 18.9 0.2 0.0018 17.8 0.2 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding zf-RING_4 PF14570.6 KXS12455.1 - 0.14 12.0 0.3 0.29 11.0 0.3 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain LTXXQ PF07813.12 KXS12455.1 - 6.3 7.6 8.8 13 6.6 4.8 2.8 2 1 1 3 3 3 0 LTXXQ motif family protein Rad60-SLD PF11976.8 KXS12456.1 - 7.6e-08 32.1 0.0 0.00046 20.0 0.0 2.5 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like F-box-like PF12937.7 KXS12457.1 - 6.1e-05 22.8 1.2 6.1e-05 22.8 1.2 2.5 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KXS12457.1 - 0.0096 15.8 0.3 0.036 14.0 0.3 2.0 1 0 0 1 1 1 1 F-box domain LRR_4 PF12799.7 KXS12459.1 - 7.2e-08 32.6 6.2 7.1e-07 29.4 0.4 2.7 2 1 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXS12459.1 - 5e-05 23.0 3.9 0.024 14.4 0.3 2.3 2 0 0 2 2 2 2 Leucine rich repeat LRR_6 PF13516.6 KXS12459.1 - 0.011 15.7 4.7 0.99 9.6 0.3 3.9 3 0 0 3 3 3 0 Leucine Rich repeat LRR_1 PF00560.33 KXS12459.1 - 0.013 16.0 2.0 1.7 9.5 0.2 3.6 3 0 0 3 3 3 0 Leucine Rich Repeat LSM PF01423.22 KXS12460.1 - 1.8e-20 72.4 0.0 2e-20 72.3 0.0 1.0 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 KXS12460.1 - 0.039 13.6 0.0 0.046 13.4 0.0 1.2 1 0 0 1 1 1 0 Hfq protein SM-ATX PF14438.6 KXS12460.1 - 0.046 13.9 0.0 0.05 13.7 0.0 1.1 1 0 0 1 1 1 0 Ataxin 2 SM domain Pkinase PF00069.25 KXS12461.1 - 2.3e-28 99.3 0.0 3e-28 98.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS12461.1 - 2.8e-10 39.9 0.0 4.2e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXS12461.1 - 0.00095 19.1 0.0 0.0018 18.2 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXS12461.1 - 0.038 12.8 0.0 0.15 10.8 0.0 1.7 1 1 0 2 2 2 0 Fungal protein kinase Kdo PF06293.14 KXS12461.1 - 0.041 13.2 0.0 0.083 12.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KXS12461.1 - 0.096 12.3 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Choline_kinase PF01633.20 KXS12461.1 - 0.24 10.9 0.0 0.37 10.3 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Tfb2 PF03849.14 KXS12462.1 - 3.9e-118 394.5 0.1 4.6e-118 394.2 0.1 1.0 1 0 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 KXS12462.1 - 2.5e-20 72.7 0.0 5.5e-20 71.6 0.0 1.6 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 KXS12462.1 - 4.6e-07 30.0 0.1 1.7e-06 28.2 0.1 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF2431 PF10354.9 KXS12463.1 - 2.4e-30 106.0 0.0 3.1e-30 105.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) Mnd1 PF03962.15 KXS12464.1 - 2.9e-25 88.3 0.9 6.4e-25 87.2 0.4 1.9 2 0 0 2 2 2 1 Mnd1 HTH domain LZ3wCH PF18517.1 KXS12464.1 - 9.7e-09 35.2 1.8 1.6e-08 34.5 0.1 2.3 2 0 0 2 2 2 1 Leucine zipper with capping helix domain LEM PF03020.15 KXS12464.1 - 0.083 12.5 0.0 0.59 9.7 0.0 2.2 2 0 0 2 2 2 0 LEM domain CCDC-167 PF15188.6 KXS12464.1 - 0.29 11.5 5.2 0.65 10.4 5.2 1.6 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 Spc24 PF08286.11 KXS12464.1 - 0.33 11.2 4.9 2.6 8.3 1.9 2.5 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 V-SNARE PF05008.15 KXS12464.1 - 0.36 11.2 4.3 2.7 8.4 3.4 2.4 1 1 1 2 2 2 0 Vesicle transport v-SNARE protein N-terminus AAA_23 PF13476.6 KXS12464.1 - 1.3 9.5 5.8 1.8 9.0 5.8 1.2 1 0 0 1 1 1 0 AAA domain DcpS PF05652.12 KXS12467.1 - 0.0023 18.7 0.0 0.0032 18.3 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal Thioredoxin_7 PF13899.6 KXS12468.1 - 4.1e-19 68.5 0.1 1.9e-18 66.4 0.0 2.1 3 0 0 3 3 3 1 Thioredoxin-like UBA_4 PF14555.6 KXS12468.1 - 3.1e-14 52.5 0.0 5.3e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.20 KXS12468.1 - 4.7e-10 39.5 0.0 1.1e-09 38.4 0.0 1.6 1 0 0 1 1 1 1 UBX domain Thioredoxin_2 PF13098.6 KXS12468.1 - 0.0012 19.3 0.1 0.0023 18.3 0.1 1.5 1 0 0 1 1 1 1 Thioredoxin-like domain Pkinase PF00069.25 KXS12469.1 - 1.3e-68 231.2 0.0 1.7e-68 230.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS12469.1 - 1.3e-51 175.4 0.0 1.7e-51 175.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXS12469.1 - 5.7e-06 25.4 0.0 8.2e-06 24.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KXS12469.1 - 0.022 14.1 0.1 0.18 11.1 0.0 2.1 2 1 0 2 2 2 0 Kinase-like Haspin_kinase PF12330.8 KXS12469.1 - 0.041 12.8 0.1 3 6.7 0.0 2.1 2 0 0 2 2 2 0 Haspin like kinase domain Acetyltransf_13 PF13880.6 KXS12470.1 - 1.1e-27 95.8 0.1 1.9e-27 95.0 0.1 1.5 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.6 KXS12470.1 - 2.4e-12 46.5 0.3 4.7e-12 45.5 0.3 1.5 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_7 PF13508.7 KXS12470.1 - 0.00096 19.5 0.0 0.002 18.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KXS12470.1 - 0.0016 18.4 0.0 0.0053 16.7 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXS12470.1 - 0.032 14.4 0.0 0.052 13.8 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Hen1_L PF12623.7 KXS12470.1 - 0.06 12.4 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 RNA repair, ligase-Pnkp-associating, region of Hen1 Mucin PF01456.17 KXS12470.1 - 0.17 11.8 2.4 0.33 10.9 2.4 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein DDE_3 PF13358.6 KXS12472.1 - 6.8e-06 25.9 0.1 7e-06 25.9 0.1 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease PH_3 PF14593.6 KXS12472.1 - 0.04 14.0 0.1 0.043 13.9 0.1 1.1 1 0 0 1 1 1 0 PH domain SH3_9 PF14604.6 KXS12473.1 - 0.00064 19.5 0.1 0.0013 18.6 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXS12473.1 - 0.0031 17.1 0.1 0.0056 16.3 0.1 1.4 1 0 0 1 1 1 1 SH3 domain ZapB PF06005.12 KXS12473.1 - 0.0057 17.1 1.8 0.021 15.2 1.8 2.0 1 0 0 1 1 1 1 Cell division protein ZapB HAP1_N PF04849.13 KXS12473.1 - 0.0089 15.3 0.4 0.015 14.5 0.4 1.2 1 0 0 1 1 1 1 HAP1 N-terminal conserved region CASP_C PF08172.12 KXS12473.1 - 0.071 12.4 1.4 0.12 11.7 1.4 1.2 1 0 0 1 1 1 0 CASP C terminal Shugoshin_N PF07558.11 KXS12473.1 - 0.14 12.0 3.9 0.11 12.4 1.4 2.1 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region DivIC PF04977.15 KXS12473.1 - 0.15 11.8 2.7 0.17 11.7 0.6 2.2 2 0 0 2 2 2 0 Septum formation initiator TSC22 PF01166.18 KXS12473.1 - 0.27 11.6 2.5 0.53 10.6 0.8 2.5 2 2 1 3 3 3 0 TSC-22/dip/bun family HALZ PF02183.18 KXS12473.1 - 0.28 11.4 4.9 0.16 12.2 0.6 2.5 2 1 1 3 3 2 0 Homeobox associated leucine zipper CENP-H PF05837.12 KXS12473.1 - 0.33 11.4 1.7 0.74 10.2 0.4 2.3 2 0 0 2 2 2 0 Centromere protein H (CENP-H) YabA PF06156.13 KXS12473.1 - 0.69 10.6 2.7 0.42 11.3 0.3 1.9 2 0 0 2 2 1 0 Initiation control protein YabA bZIP_Maf PF03131.17 KXS12473.1 - 0.95 10.0 7.2 7.6 7.1 2.4 2.6 1 1 1 2 2 2 0 bZIP Maf transcription factor Mod_r PF07200.13 KXS12473.1 - 1.3 9.1 4.7 0.24 11.5 0.5 1.8 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein bZIP_1 PF00170.21 KXS12473.1 - 1.9 8.6 6.7 0.18 11.9 0.4 2.4 2 0 0 2 2 2 0 bZIP transcription factor DUF1236 PF06823.12 KXS12474.1 - 0.24 11.3 2.8 0.31 10.9 0.0 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1236) ANTH PF07651.16 KXS12475.1 - 4.2e-58 196.5 0.0 4.2e-58 196.5 0.0 3.0 3 1 0 3 3 3 1 ANTH domain I_LWEQ PF01608.17 KXS12475.1 - 5.7e-48 163.0 18.3 5.7e-48 163.0 18.3 7.0 3 2 4 7 7 7 2 I/LWEQ domain Glyco_hydro_19 PF00182.19 KXS12476.1 - 2.4e-07 30.9 0.0 1.1e-06 28.7 0.1 1.8 1 1 1 2 2 2 1 Chitinase class I Thiolase_N PF00108.23 KXS12477.1 - 3.8e-17 62.5 0.0 1.6e-13 50.7 0.0 2.3 1 1 1 2 2 2 2 Thiolase, N-terminal domain Thiolase_C PF02803.18 KXS12477.1 - 1.4e-10 40.9 0.1 5.3e-10 39.0 0.1 2.1 2 0 0 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III PF08545.10 KXS12477.1 - 0.0039 17.0 0.0 0.11 12.4 0.0 2.8 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.26 KXS12477.1 - 0.005 16.5 0.5 0.031 13.9 0.2 2.4 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KXS12477.1 - 0.039 14.0 0.2 1.3 9.1 0.1 2.8 2 1 0 2 2 2 0 Beta-ketoacyl synthase, C-terminal domain Pmp3 PF01679.17 KXS12478.1 - 7.1e-11 42.1 16.5 9.7e-10 38.5 16.5 2.1 1 1 0 1 1 1 1 Proteolipid membrane potential modulator CH PF00307.31 KXS12480.1 - 7.3e-20 71.2 0.0 9.5e-20 70.8 0.0 1.2 1 0 0 1 1 1 1 Calponin homology (CH) domain Calponin PF00402.18 KXS12480.1 - 2.5e-07 30.2 11.8 0.00069 19.2 2.2 2.4 2 0 0 2 2 2 2 Calponin family repeat CDC24 PF06395.11 KXS12480.1 - 0.0089 16.3 0.1 0.013 15.8 0.1 1.3 1 0 0 1 1 1 1 CDC24 Calponin zf-C3HC4_3 PF13920.6 KXS12481.1 - 4.4e-10 39.3 2.2 6.3e-10 38.8 2.2 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KXS12481.1 - 0.32 10.9 3.4 0.61 10.0 3.4 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KXS12481.1 - 0.55 10.6 3.9 0.9 9.9 3.9 1.4 1 0 0 1 1 1 0 Ring finger domain RNB PF00773.19 KXS12482.1 - 0.15 11.4 0.0 0.28 10.5 0.0 1.4 1 0 0 1 1 1 0 RNB domain Alanine_zipper PF11839.8 KXS12483.1 - 0.54 10.7 6.9 1.3 9.5 6.9 1.6 1 1 0 1 1 1 0 Alanine-zipper, major outer membrane lipoprotein Reeler PF02014.16 KXS12484.1 - 1.4e-08 35.6 0.1 2.7e-08 34.6 0.1 1.5 1 0 0 1 1 1 1 Reeler domain Aldedh PF00171.22 KXS12485.1 - 2.5e-133 445.0 0.1 2.8e-133 444.8 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KXS12485.1 - 0.18 10.8 0.0 0.29 10.1 0.0 1.3 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) Transket_pyr PF02779.24 KXS12486.1 - 1.5e-61 207.1 0.0 3.8e-61 205.9 0.0 1.7 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 KXS12486.1 - 1.2e-58 198.4 0.0 1.9e-58 197.8 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 KXS12486.1 - 2.2e-51 173.5 0.0 3.8e-51 172.8 0.0 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 KXS12486.1 - 1.1e-10 40.9 0.8 2.6e-10 39.7 0.8 1.7 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus Cyclin_N PF00134.23 KXS12487.1 - 1.6e-09 37.6 0.0 2.7e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Glyco_hydro_cc PF11790.8 KXS12489.1 - 1.7e-44 152.2 0.0 3e-44 151.4 0.0 1.4 1 1 1 2 2 2 1 Glycosyl hydrolase catalytic core DUF1180 PF06679.12 KXS12489.1 - 2.9 8.3 3.9 4.1 7.8 3.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Sec62 PF03839.16 KXS12490.1 - 9.5e-47 159.3 6.5 5e-46 156.9 6.5 1.7 1 1 0 1 1 1 1 Translocation protein Sec62 Peptidase_U4 PF03419.13 KXS12490.1 - 1 8.6 6.5 1.4 8.1 6.5 1.2 1 0 0 1 1 1 0 Sporulation factor SpoIIGA STAG PF08514.11 KXS12491.1 - 2.3e-08 33.9 0.0 1.2e-07 31.6 0.0 2.3 2 0 0 2 2 2 1 STAG domain BP28CT PF08146.12 KXS12491.1 - 0.12 12.2 0.1 2 8.2 0.2 2.5 2 0 0 2 2 2 0 BP28CT (NUC211) domain Kelch_5 PF13854.6 KXS12492.1 - 2.7e-10 40.0 6.7 9e-05 22.4 0.0 5.3 6 0 0 6 6 6 3 Kelch motif Kelch_4 PF13418.6 KXS12492.1 - 1.5e-08 34.5 7.1 0.012 15.6 0.0 4.7 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_1 PF01344.25 KXS12492.1 - 1.1e-07 31.3 6.9 2.4e-05 23.8 2.7 3.9 3 1 0 3 3 3 2 Kelch motif Kelch_6 PF13964.6 KXS12492.1 - 2e-05 24.7 5.1 0.35 11.2 0.0 4.1 3 1 0 3 3 3 2 Kelch motif Kelch_2 PF07646.15 KXS12492.1 - 0.0041 17.0 7.2 0.16 12.0 0.0 4.2 4 0 0 4 4 4 1 Kelch motif Dimer_Tnp_hAT PF05699.14 KXS12493.1 - 1.7e-16 59.8 0.0 2.6e-16 59.2 0.0 1.3 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4413 PF14372.6 KXS12493.1 - 0.024 15.0 0.3 0.064 13.6 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4413) VASt PF16016.5 KXS12495.1 - 8.1e-18 65.3 0.0 1.5e-17 64.4 0.0 1.5 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 KXS12495.1 - 1.8e-05 24.6 0.0 3.4e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 GRAM domain PMM PF03332.13 KXS12496.1 - 1.3e-101 339.0 0.0 1.5e-101 338.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 KXS12496.1 - 0.017 14.8 0.0 4.2 7.0 0.0 2.1 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Use1 PF09753.9 KXS12497.1 - 0.039 13.7 0.0 0.046 13.4 0.0 1.1 1 0 0 1 1 1 0 Membrane fusion protein Use1 Fungal_trans PF04082.18 KXS12498.1 - 0.034 13.2 0.0 0.034 13.2 0.0 1.0 1 0 0 1 1 1 0 Fungal specific transcription factor domain Methyltransf_8 PF05148.15 KXS12499.1 - 3e-63 213.6 0.0 7.5e-52 176.3 0.0 3.0 2 1 0 2 2 2 2 Hypothetical methyltransferase Methyltransf_11 PF08241.12 KXS12499.1 - 8.4e-05 23.1 0.1 0.00027 21.5 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXS12499.1 - 0.0009 19.9 0.1 0.011 16.5 0.1 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXS12499.1 - 0.0063 16.3 0.1 0.55 10.0 0.0 2.5 3 0 0 3 3 3 1 Methyltransferase domain Mito_carr PF00153.27 KXS12500.1 - 9e-46 153.7 2.1 1.7e-16 59.9 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PrcB_C PF14343.6 KXS12500.1 - 0.25 11.5 0.9 2.6 8.3 0.0 2.5 2 0 0 2 2 2 0 PrcB C-terminal MtrF PF09472.10 KXS12500.1 - 3.1 7.3 6.1 0.35 10.3 0.3 2.4 3 0 0 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) Pam16 PF03656.13 KXS12501.1 - 3.8e-30 104.5 0.0 4.4e-30 104.3 0.0 1.0 1 0 0 1 1 1 1 Pam16 MerR_1 PF13411.6 KXS12501.1 - 0.083 13.0 0.0 0.15 12.2 0.0 1.4 1 1 0 1 1 1 0 MerR HTH family regulatory protein ATP_bind_1 PF03029.17 KXS12502.1 - 8.9e-47 159.9 0.0 2.2e-46 158.6 0.0 1.6 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein Got1 PF04178.12 KXS12504.1 - 4.4e-17 62.5 6.9 5e-14 52.7 3.3 2.4 1 1 1 2 2 2 2 Got1/Sft2-like family 4HBT PF03061.22 KXS12504.1 - 7.5e-09 35.8 0.0 1.8e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.6 KXS12504.1 - 0.00092 19.4 0.0 0.0016 18.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4442) UMP1 PF05348.11 KXS12505.1 - 2.8e-28 98.5 0.0 3.7e-28 98.1 0.0 1.2 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 Pkinase PF00069.25 KXS12506.1 - 2.1e-54 184.7 0.0 2.4e-54 184.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS12506.1 - 3.5e-26 92.0 0.0 3.9e-26 91.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXS12506.1 - 5.4e-07 28.7 0.0 6.8e-07 28.4 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KXS12506.1 - 1.8e-05 24.2 0.0 2.7e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KXS12506.1 - 5.5e-05 22.6 0.0 8.5e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Occludin_ELL PF07303.13 KXS12509.1 - 0.14 12.9 0.4 0.27 12.0 0.4 1.5 1 1 0 1 1 1 0 Occludin homology domain Arginosuc_synth PF00764.19 KXS12510.1 - 1.2e-159 531.8 0.0 1.4e-159 531.6 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 KXS12510.1 - 4.7e-05 23.0 0.1 9.1e-05 22.0 0.1 1.4 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 KXS12510.1 - 0.0072 15.2 0.0 0.01 14.6 0.0 1.2 1 0 0 1 1 1 1 tRNA methyl transferase Collagen PF01391.18 KXS12512.1 - 9.3e-06 25.3 11.7 2e-05 24.2 11.7 1.6 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) Methyltransf_25 PF13649.6 KXS12513.1 - 1e-07 32.5 0.0 2e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXS12513.1 - 1.9e-06 28.5 0.0 3.2e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXS12513.1 - 3.8e-05 23.5 0.0 5.8e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXS12513.1 - 7e-05 22.3 0.0 0.00017 21.0 0.0 1.6 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KXS12513.1 - 0.027 15.2 0.0 0.043 14.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain adh_short_C2 PF13561.6 KXS12514.1 - 6.8e-52 176.3 0.2 5e-36 124.4 0.0 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXS12514.1 - 4e-40 137.4 0.0 6e-40 136.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXS12514.1 - 2.1e-14 53.8 0.0 3.6e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXS12514.1 - 0.0011 18.5 0.1 0.0016 18.0 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXS12514.1 - 0.0012 18.3 0.0 0.0016 17.9 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase HHH_5 PF14520.6 KXS12514.1 - 0.14 12.8 0.8 0.27 11.9 0.8 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix domain tRNA_int_endo PF01974.17 KXS12516.1 - 7.8e-08 32.3 0.0 1.7e-07 31.2 0.0 1.6 1 1 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain SelK_SelG PF10961.8 KXS12516.1 - 1.2 9.8 5.1 2.4 8.8 5.1 1.4 1 0 0 1 1 1 0 Selenoprotein SelK_SelG MTS PF05175.14 KXS12517.1 - 8.4e-09 35.2 0.0 1.2e-06 28.1 0.0 2.1 2 0 0 2 2 2 2 Methyltransferase small domain Methyltransf_25 PF13649.6 KXS12517.1 - 0.00012 22.7 0.0 0.00026 21.6 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_24 PF13578.6 KXS12517.1 - 0.0011 19.9 0.0 0.015 16.3 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXS12517.1 - 0.031 14.9 0.0 0.12 13.1 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.12 KXS12517.1 - 0.047 14.4 0.0 0.33 11.7 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain DUF938 PF06080.12 KXS12517.1 - 0.052 13.3 0.0 0.077 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) PrmA PF06325.13 KXS12517.1 - 0.077 12.4 0.0 0.17 11.2 0.0 1.5 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Pribosyl_synth PF14572.6 KXS12518.1 - 6.7e-39 133.8 0.4 1.5e-38 132.7 0.4 1.6 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 KXS12518.1 - 1.3e-35 121.9 0.7 5.4e-35 119.8 0.1 2.3 3 0 0 3 3 3 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 KXS12518.1 - 2e-14 53.4 0.7 5.2e-14 52.1 0.3 1.8 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KXS12518.1 - 0.11 11.9 0.5 0.23 10.9 0.5 1.4 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase YbfN PF13982.6 KXS12519.1 - 0.034 14.4 0.1 0.049 13.9 0.1 1.2 1 0 0 1 1 1 0 YbfN-like lipoprotein DEC-1_N PF04625.13 KXS12520.1 - 0.18 10.8 0.6 0.23 10.4 0.3 1.3 1 1 0 1 1 1 0 DEC-1 protein, N-terminal region ArsB PF02040.15 KXS12521.1 - 2e-27 96.6 20.4 3e-16 59.8 8.6 2.1 2 0 0 2 2 2 2 Arsenical pump membrane protein CitMHS PF03600.16 KXS12521.1 - 1.5e-26 93.3 12.3 1.9e-25 89.7 4.0 2.2 1 1 1 2 2 2 2 Citrate transporter OATP PF03137.20 KXS12521.1 - 0.024 12.9 0.4 0.052 11.8 0.4 1.5 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Flavin_Reduct PF01613.18 KXS12522.1 - 7.5e-16 58.5 0.1 1.1e-15 58.1 0.1 1.1 1 0 0 1 1 1 1 Flavin reductase like domain Polysacc_deac_1 PF01522.21 KXS12523.1 - 0.017 15.0 0.0 0.033 14.1 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide deacetylase ELFV_dehydrog PF00208.21 KXS12524.1 - 2.8e-57 194.2 0.0 8.4e-57 192.7 0.0 1.8 2 0 0 2 2 2 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 KXS12524.1 - 4e-22 77.7 0.0 2.3e-15 55.3 0.0 2.1 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.18 KXS12524.1 - 0.037 13.9 0.0 0.36 10.7 0.0 2.5 2 0 0 2 2 2 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain CEND1 PF15677.5 KXS12525.1 - 0.091 13.3 3.0 0.084 13.4 1.3 1.9 1 1 0 1 1 1 0 Cell cycle exit and neuronal differentiation protein 1 SKG6 PF08693.10 KXS12525.1 - 0.18 11.3 3.8 0.39 10.2 3.8 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF3040 PF11239.8 KXS12525.1 - 0.98 9.7 3.8 0.73 10.1 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) AA_permease_2 PF13520.6 KXS12526.1 - 1.5e-17 63.6 34.7 2.6e-17 62.8 34.7 1.3 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXS12526.1 - 7.8e-09 34.6 31.4 2.6e-08 32.9 31.2 1.7 1 1 0 1 1 1 1 Amino acid permease Tetraspanin PF00335.20 KXS12526.1 - 0.019 14.7 0.8 0.044 13.5 0.2 1.9 2 0 0 2 2 2 0 Tetraspanin family PRA1 PF03208.19 KXS12527.1 - 0.42 10.2 12.7 0.48 10.0 12.7 1.1 1 0 0 1 1 1 0 PRA1 family protein DUF5313 PF17240.2 KXS12527.1 - 0.51 10.8 4.8 0.62 10.5 4.8 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5313) Wzy_C PF04932.15 KXS12527.1 - 3.9 7.1 8.9 4.8 6.8 8.9 1.2 1 0 0 1 1 1 0 O-Antigen ligase S_4TM PF18159.1 KXS12527.1 - 8.2 5.6 6.8 8.9 5.5 6.8 1.1 1 0 0 1 1 1 0 SMODS-associating 4TM effector domain PurS PF02700.14 KXS12528.1 - 0.13 12.5 1.5 2.7 8.2 0.1 3.2 3 1 0 3 3 3 0 Phosphoribosylformylglycinamidine (FGAM) synthase Amidohydro_1 PF01979.20 KXS12530.1 - 3.2e-68 230.6 3.4 4.9e-68 230.0 3.4 1.2 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.20 KXS12530.1 - 3e-56 189.0 1.0 7e-56 187.8 1.0 1.7 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_beta PF00699.20 KXS12530.1 - 5.9e-41 138.5 0.1 1.9e-40 136.8 0.1 1.9 1 0 0 1 1 1 1 Urease beta subunit Urease_gamma PF00547.18 KXS12530.1 - 6.7e-41 138.6 0.1 1.5e-40 137.5 0.1 1.7 1 0 0 1 1 1 1 Urease, gamma subunit Amidohydro_3 PF07969.11 KXS12530.1 - 7.8e-07 28.9 0.6 2.3e-06 27.4 0.0 2.1 3 0 0 3 3 3 1 Amidohydrolase family LRR_8 PF13855.6 KXS12532.1 - 4.5e-05 23.1 12.9 0.0024 17.6 6.8 2.3 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KXS12532.1 - 8e-05 22.9 11.2 0.00066 20.0 1.9 3.1 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KXS12532.1 - 0.31 11.2 2.9 2.5 8.4 0.2 2.9 2 0 0 2 2 2 0 Leucine Rich repeat UQ_con PF00179.26 KXS12533.1 - 2.9e-18 65.9 0.8 3.1e-18 65.8 0.8 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KXS12533.1 - 0.08 13.2 0.5 0.13 12.5 0.3 1.5 1 1 0 1 1 1 0 RWD domain DUF1003 PF06210.11 KXS12534.1 - 1.7e-28 98.7 1.1 2.8e-28 98.0 1.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1003) DUF667 PF05018.13 KXS12537.1 - 2.1e-93 311.2 1.2 2.3e-93 311.1 1.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF667) DDE_1 PF03184.19 KXS12537.1 - 0.1 12.2 0.1 0.13 11.9 0.1 1.2 1 0 0 1 1 1 0 DDE superfamily endonuclease NAC PF01849.18 KXS12538.1 - 3.2e-23 81.4 1.0 4.9e-23 80.9 1.0 1.3 1 0 0 1 1 1 1 NAC domain DNA_pol_E_B PF04042.16 KXS12539.1 - 2.6e-45 154.4 0.1 4e-45 153.8 0.1 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DUF5601 PF18151.1 KXS12539.1 - 0.0099 16.2 0.0 0.019 15.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5601) EHN PF06441.12 KXS12540.1 - 6.9e-21 74.6 0.1 1.4e-20 73.6 0.1 1.5 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KXS12540.1 - 0.13 11.9 0.5 0.44 10.1 0.1 2.2 3 0 0 3 3 3 0 alpha/beta hydrolase fold DNA_primase_S PF01896.19 KXS12541.1 - 1.1e-55 188.4 0.1 1.5e-55 188.0 0.1 1.2 1 0 0 1 1 1 1 DNA primase small subunit adh_short_C2 PF13561.6 KXS12542.1 - 3.3e-21 75.9 0.0 7.6e-18 64.9 0.0 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXS12542.1 - 2.4e-10 40.2 0.0 3.7e-08 33.0 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase Rhodanese PF00581.20 KXS12544.1 - 2.2e-12 47.4 0.0 2.8e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain DUF543 PF04418.12 KXS12545.1 - 1.3e-23 82.8 0.0 1.4e-23 82.7 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF543) TMEM171 PF15471.6 KXS12545.1 - 0.075 12.0 0.0 0.083 11.9 0.0 1.1 1 0 0 1 1 1 0 Transmembrane protein family 171 Cullin_binding PF03556.15 KXS12546.1 - 5.6e-19 68.8 0.2 8.4e-19 68.2 0.2 1.2 1 0 0 1 1 1 1 Cullin binding Pyr_redox_2 PF07992.14 KXS12547.1 - 5.4e-54 183.4 0.2 9.6e-54 182.6 0.2 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KXS12547.1 - 1.8e-30 105.4 0.0 1.8e-29 102.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Glutaredoxin PF00462.24 KXS12547.1 - 2.9e-17 62.6 0.0 5.6e-17 61.7 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin Pyr_redox PF00070.27 KXS12547.1 - 3.7e-17 62.6 0.5 7.2e-13 48.9 0.0 3.4 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXS12547.1 - 4.3e-11 42.6 0.2 4.8e-07 29.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXS12547.1 - 2e-06 27.1 0.7 6.3e-06 25.5 0.4 1.9 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 KXS12547.1 - 5.4e-05 22.1 0.2 0.00056 18.7 0.1 2.3 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.6 KXS12547.1 - 0.0004 20.6 0.8 0.013 15.7 0.1 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KXS12547.1 - 0.00098 18.4 0.3 0.0022 17.3 0.3 1.5 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 KXS12547.1 - 0.0015 17.7 0.1 0.0026 16.9 0.1 1.5 1 0 0 1 1 1 1 Glucose inhibited division protein A Thioredoxin_3 PF13192.6 KXS12547.1 - 0.0019 18.2 0.0 0.0061 16.6 0.0 1.8 2 0 0 2 2 1 1 Thioredoxin domain AlaDh_PNT_C PF01262.21 KXS12547.1 - 0.0022 17.3 0.0 0.21 10.9 0.0 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 KXS12547.1 - 0.0033 16.8 0.0 0.0051 16.2 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thioredoxin PF00085.20 KXS12547.1 - 0.0055 16.7 0.0 0.01 15.8 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin K_oxygenase PF13434.6 KXS12547.1 - 0.015 14.5 0.1 0.35 10.0 0.0 2.3 1 1 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KXS12547.1 - 0.021 14.4 2.4 0.099 12.2 2.3 2.2 1 1 0 1 1 1 0 FAD dependent oxidoreductase GST_N_2 PF13409.6 KXS12547.1 - 0.13 12.6 0.0 0.26 11.6 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Thioredoxin_2 PF13098.6 KXS12547.1 - 0.13 12.7 0.0 0.46 11.0 0.0 1.9 1 0 0 1 1 1 0 Thioredoxin-like domain GST_N_3 PF13417.6 KXS12547.1 - 0.16 12.4 0.0 0.3 11.5 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Nup160 PF11715.8 KXS12548.1 - 0.079 11.6 0.0 0.079 11.6 0.0 1.1 1 0 0 1 1 1 0 Nucleoporin Nup120/160 HgmA PF04209.13 KXS12549.1 - 4.6e-174 579.1 0.3 8.3e-174 578.3 0.3 1.4 1 1 0 1 1 1 1 homogentisate 1,2-dioxygenase DUF2367 PF10164.9 KXS12550.1 - 1.3e-14 54.5 6.4 2.1e-14 53.9 6.4 1.5 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2367) IPK PF03770.16 KXS12551.1 - 6.5e-42 143.6 0.1 7.8e-42 143.4 0.1 1.1 1 0 0 1 1 1 1 Inositol polyphosphate kinase START PF01852.19 KXS12552.1 - 0.042 13.3 0.0 0.048 13.1 0.0 1.2 1 0 0 1 1 1 0 START domain MT0933_antitox PF14013.6 KXS12552.1 - 6.4 7.2 6.1 11 6.4 2.3 2.7 2 1 0 2 2 2 0 MT0933-like antitoxin protein Syntaxin PF00804.25 KXS12553.1 - 1.8e-17 63.7 10.3 3.1e-17 62.9 10.3 1.3 1 0 0 1 1 1 1 Syntaxin SNARE PF05739.19 KXS12553.1 - 1e-06 28.6 1.8 3.8e-06 26.8 1.8 2.0 1 0 0 1 1 1 1 SNARE domain Syntaxin_2 PF14523.6 KXS12553.1 - 0.0012 19.1 10.6 0.0018 18.6 4.2 2.5 2 0 0 2 2 2 1 Syntaxin-like protein XkdW PF09636.10 KXS12553.1 - 0.16 12.1 0.5 0.41 10.8 0.0 1.9 2 0 0 2 2 2 0 XkdW protein 4HB_MCP_1 PF12729.7 KXS12553.1 - 0.36 10.3 10.0 1.4 8.4 0.8 3.0 2 1 1 3 3 3 0 Four helix bundle sensory module for signal transduction Med9 PF07544.13 KXS12553.1 - 0.7 10.0 7.9 0.15 12.2 3.6 2.2 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 V-SNARE PF05008.15 KXS12553.1 - 1.8 9.0 9.5 0.57 10.6 3.7 2.8 2 1 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus H-kinase_dim PF02895.14 KXS12553.1 - 9.3 6.7 10.5 2.9 8.3 1.9 2.9 2 1 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain Pkinase PF00069.25 KXS12554.1 - 2.1e-57 194.5 0.0 2e-56 191.3 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS12554.1 - 1.4e-24 86.8 0.0 2.4e-17 63.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KXS12554.1 - 8.2e-05 22.6 1.8 0.00042 20.3 0.5 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KXS12554.1 - 0.006 16.0 0.7 0.018 14.4 0.1 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KXS12554.1 - 0.022 14.1 0.1 0.18 11.1 0.0 2.1 2 0 0 2 2 2 0 Kinase-like FTA2 PF13095.6 KXS12554.1 - 0.059 13.0 0.0 3.1 7.4 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 KXS12554.1 - 0.25 10.2 0.0 0.36 9.7 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain BTB_2 PF02214.22 KXS12556.1 - 5.4e-08 33.1 0.0 1.3e-07 31.9 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain IFP_35_N PF07334.13 KXS12556.1 - 0.15 12.1 0.1 0.3 11.2 0.1 1.4 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus NARP1 PF12569.8 KXS12558.1 - 5.7e-176 586.4 16.4 5.7e-176 586.4 16.4 2.4 2 1 1 3 3 3 1 NMDA receptor-regulated protein 1 TPR_2 PF07719.17 KXS12558.1 - 1.3e-14 53.1 19.2 0.00025 20.9 0.4 9.0 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_16 PF13432.6 KXS12558.1 - 7.2e-13 49.0 11.8 0.058 14.0 0.1 8.1 8 1 0 8 8 8 3 Tetratricopeptide repeat TPR_14 PF13428.6 KXS12558.1 - 8.6e-11 41.7 13.5 0.098 13.5 0.1 9.0 6 2 2 9 9 8 2 Tetratricopeptide repeat TPR_1 PF00515.28 KXS12558.1 - 1.7e-10 40.3 11.7 0.0032 17.2 0.9 6.4 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 KXS12558.1 - 2.6e-09 36.5 11.2 0.00072 19.6 0.4 7.1 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 KXS12558.1 - 1e-07 32.3 14.8 0.091 13.3 0.1 6.9 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_11 PF13414.6 KXS12558.1 - 3.8e-07 29.7 6.8 0.0002 21.0 0.2 5.1 5 0 0 5 5 5 1 TPR repeat TPR_7 PF13176.6 KXS12558.1 - 6.9e-06 25.7 4.4 1.4 9.1 0.1 5.4 4 0 0 4 4 4 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KXS12558.1 - 1.7e-05 24.8 11.1 0.067 13.3 0.2 6.1 5 2 2 7 7 7 2 Fis1 C-terminal tetratricopeptide repeat TPR_9 PF13371.6 KXS12558.1 - 1.8e-05 24.8 7.1 0.012 15.7 0.2 6.2 7 1 1 8 8 7 1 Tetratricopeptide repeat TPR_15 PF13429.6 KXS12558.1 - 3.1e-05 23.3 6.0 9.7e-05 21.7 0.6 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 KXS12558.1 - 4.3e-05 23.7 13.5 0.89 9.9 0.4 6.4 5 1 0 5 5 5 1 Tetratricopeptide repeat NatB_MDM20 PF09797.9 KXS12558.1 - 0.00022 20.3 3.7 0.00056 19.0 0.1 3.0 2 1 0 2 2 2 1 N-acetyltransferase B complex (NatB) non catalytic subunit ANAPC3 PF12895.7 KXS12558.1 - 0.00062 19.9 10.6 12 6.1 0.0 6.0 5 1 1 6 6 6 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 KXS12558.1 - 0.0035 17.9 1.1 22 6.0 0.0 5.0 5 0 0 5 5 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 KXS12558.1 - 0.0035 17.6 4.2 4.2 8.0 0.0 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 KXS12558.1 - 0.029 14.0 1.5 1.9 8.1 0.0 3.2 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) BTAD PF03704.17 KXS12558.1 - 1.3 9.4 6.1 1.5 9.3 0.8 3.2 2 1 1 3 3 3 0 Bacterial transcriptional activator domain DUF2681 PF10883.8 KXS12558.1 - 7.2 7.1 7.5 21 5.6 7.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2681) Rad60-SLD_2 PF13881.6 KXS12559.1 - 4.6e-17 62.1 0.2 8.3e-17 61.3 0.0 1.4 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KXS12559.1 - 2.1e-05 24.2 0.0 4.9e-05 23.0 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin family EF-hand_1 PF00036.32 KXS12560.1 - 5.6e-37 122.5 17.0 2.2e-09 36.2 1.2 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KXS12560.1 - 1.3e-31 108.8 9.1 2.8e-16 59.7 0.4 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KXS12560.1 - 1.3e-28 96.4 9.5 2.9e-09 36.1 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 KXS12560.1 - 4.6e-27 93.6 10.4 2.4e-12 46.5 0.9 3.8 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 KXS12560.1 - 2e-19 68.1 15.8 1.2e-05 24.6 0.2 4.4 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 KXS12560.1 - 5.7e-14 52.2 0.1 5.1e-06 26.7 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 KXS12560.1 - 3.9e-06 26.8 4.4 0.17 11.9 0.4 3.3 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 KXS12560.1 - 2.5e-05 24.5 0.2 0.17 12.2 0.0 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region SurA_N_3 PF13624.6 KXS12560.1 - 0.00016 21.5 1.3 0.32 10.8 0.2 2.1 1 1 1 2 2 2 2 SurA N-terminal domain EF-hand_14 PF17959.1 KXS12560.1 - 0.0037 17.6 1.3 2.6 8.5 0.2 2.4 1 1 1 2 2 2 2 EF-hand domain SurA_N_2 PF13623.6 KXS12560.1 - 0.004 17.0 0.5 1.4 8.8 0.1 2.3 2 0 0 2 2 2 2 SurA N-terminal domain Dockerin_1 PF00404.18 KXS12560.1 - 0.006 16.8 0.3 0.92 9.8 0.1 2.6 2 1 0 2 2 2 1 Dockerin type I domain HTH_40 PF14493.6 KXS12560.1 - 0.0097 16.3 3.4 0.78 10.2 1.2 2.5 1 1 1 2 2 2 1 Helix-turn-helix domain Sigma54_CBD PF04963.13 KXS12560.1 - 0.011 15.5 0.2 0.015 15.1 0.2 1.2 1 0 0 1 1 1 0 Sigma-54 factor, core binding domain EF-hand_11 PF08976.11 KXS12560.1 - 0.013 16.4 0.4 0.93 10.4 0.0 2.1 1 1 1 2 2 2 0 EF-hand domain DUF3911 PF13050.6 KXS12560.1 - 0.071 13.2 1.2 3.4 7.8 0.1 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3911) Caleosin PF05042.13 KXS12560.1 - 0.098 12.6 1.2 9.3 6.1 0.0 3.3 1 1 2 3 3 3 0 Caleosin related protein UPF0154 PF03672.13 KXS12560.1 - 0.1 12.6 0.2 9.4 6.3 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) DUF21 PF01595.20 KXS12560.1 - 0.11 12.2 1.2 0.73 9.5 0.5 2.1 2 0 0 2 2 2 0 Cyclin M transmembrane N-terminal domain DUF3349 PF11829.8 KXS12560.1 - 0.12 13.1 1.0 23 5.9 0.1 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF3349) FlgD PF03963.14 KXS12560.1 - 0.17 12.2 0.0 0.59 10.5 0.0 1.9 2 0 0 2 2 2 0 Flagellar hook capping protein - N-terminal region LETM1 PF07766.13 KXS12560.1 - 0.22 10.9 2.0 0.3 10.4 1.1 1.8 1 1 0 1 1 1 0 LETM1-like protein MgtE_N PF03448.17 KXS12560.1 - 0.31 11.7 3.2 0.23 12.1 0.6 2.1 3 0 0 3 3 2 0 MgtE intracellular N domain EF-hand_10 PF14788.6 KXS12560.1 - 1 9.3 5.9 1.9 8.4 0.9 3.0 2 1 1 3 3 3 0 EF hand EHN PF06441.12 KXS12563.1 - 3.3e-33 114.3 0.1 6.8e-33 113.3 0.1 1.5 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KXS12563.1 - 1.3e-17 64.3 0.0 1.2e-16 61.2 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXS12563.1 - 2.1e-05 25.3 0.2 5.7e-05 23.8 0.0 1.8 2 1 0 2 2 2 1 Alpha/beta hydrolase family Putative_PNPOx PF01243.20 KXS12564.1 - 0.00041 20.5 0.0 0.00085 19.5 0.0 1.5 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase eIF-3_zeta PF05091.12 KXS12565.1 - 1.4e-123 413.7 0.0 1.7e-123 413.4 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) FoP_duplication PF13865.6 KXS12565.1 - 5.6 7.6 9.9 11 6.7 9.9 1.4 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 GFO_IDH_MocA PF01408.22 KXS12567.1 - 1.4e-20 74.3 0.1 2.7e-20 73.4 0.1 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold ubiquitin PF00240.23 KXS12568.1 - 0.038 13.8 0.0 0.054 13.3 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin family DUF1534 PF07551.11 KXS12570.1 - 0.053 13.3 0.1 0.083 12.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1534) RPN1_RPN2_N PF17781.1 KXS12571.1 - 2.2e-124 414.9 1.1 3.7e-124 414.1 1.1 1.4 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 KXS12571.1 - 3.1e-30 104.0 0.1 8.3e-30 102.6 0.1 1.8 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 KXS12571.1 - 4.3e-22 77.4 24.6 3.3e-07 30.4 0.1 7.9 8 0 0 8 8 7 5 Proteasome/cyclosome repeat zf-C2H2 PF00096.26 KXS12571.1 - 5.8e-10 39.1 10.4 0.00031 21.0 0.1 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KXS12571.1 - 2.4e-08 34.0 8.8 5.9e-07 29.6 1.6 2.7 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KXS12571.1 - 1.2e-06 28.9 10.6 0.0061 17.3 0.1 3.1 3 0 0 3 3 2 2 C2H2-type zinc finger zf-C2HE PF16278.5 KXS12571.1 - 0.0011 19.4 1.0 0.027 14.9 0.3 2.8 2 0 0 2 2 2 1 C2HE / C2H2 / C2HC zinc-binding finger HEAT_2 PF13646.6 KXS12571.1 - 0.012 16.0 0.4 2 8.9 0.0 3.2 3 0 0 3 3 2 0 HEAT repeats DUF5320 PF17253.2 KXS12571.1 - 0.039 15.0 0.6 0.11 13.5 0.6 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5320) zf-C2H2_jaz PF12171.8 KXS12571.1 - 0.064 13.6 0.2 11 6.5 0.0 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Cript PF10235.9 KXS12571.1 - 0.091 13.3 0.9 0.24 12.0 0.9 1.6 1 0 0 1 1 1 0 Microtubule-associated protein CRIPT zf-Di19 PF05605.12 KXS12571.1 - 0.78 10.1 4.6 0.27 11.5 0.4 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-LYAR PF08790.11 KXS12571.1 - 0.97 9.4 6.0 12 5.9 0.1 2.7 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-C2H2_11 PF16622.5 KXS12571.1 - 1.1 9.0 6.5 2.8 7.8 2.9 2.4 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 KXS12571.1 - 1.2 9.2 5.7 1.9 8.6 0.1 2.9 3 0 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KXS12571.1 - 3.2 7.6 13.9 0.037 13.8 4.2 2.7 3 0 0 3 3 3 0 C2H2-type zinc-finger domain CLP_protease PF00574.23 KXS12572.1 - 5e-74 248.1 0.0 6.1e-74 247.8 0.0 1.1 1 0 0 1 1 1 1 Clp protease Csm1_N PF18504.1 KXS12573.1 - 0.015 15.6 2.6 0.015 15.6 2.6 1.8 2 0 0 2 2 2 0 Csm1 N-terminal domain DUF4515 PF14988.6 KXS12573.1 - 0.021 14.7 0.5 0.036 13.9 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4515) ZapB PF06005.12 KXS12573.1 - 0.03 14.7 4.9 0.034 14.6 2.0 2.0 2 0 0 2 2 2 0 Cell division protein ZapB Med21 PF11221.8 KXS12573.1 - 0.052 13.8 0.6 0.052 13.8 0.6 1.5 2 0 0 2 2 2 0 Subunit 21 of Mediator complex Spc29 PF17082.5 KXS12573.1 - 0.12 12.2 2.2 0.15 11.9 1.8 1.4 1 1 1 2 2 2 0 Spindle Pole Component 29 DUF1465 PF07323.12 KXS12573.1 - 0.14 12.0 0.1 1.4 8.8 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1465) DUF3972 PF13118.6 KXS12573.1 - 0.15 12.5 1.9 0.28 11.6 1.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3972) DUF948 PF06103.11 KXS12573.1 - 0.19 12.0 1.8 0.38 11.0 0.3 1.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) TSC22 PF01166.18 KXS12573.1 - 0.19 12.1 3.4 1.2 9.5 0.1 2.3 2 1 0 2 2 2 0 TSC-22/dip/bun family Cep57_CLD_2 PF14197.6 KXS12573.1 - 0.25 11.5 4.0 0.15 12.1 2.0 1.6 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 FlaC_arch PF05377.11 KXS12573.1 - 0.52 10.8 3.7 19 5.7 0.1 2.8 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Ank_2 PF12796.7 KXS12576.1 - 6.7e-23 81.1 0.2 2.2e-10 41.0 0.2 3.3 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXS12576.1 - 4.1e-20 71.9 0.4 2.2e-09 37.6 0.1 4.9 4 2 1 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXS12576.1 - 4.1e-17 60.5 0.3 0.03 14.8 0.0 7.3 8 0 0 8 8 8 4 Ankyrin repeat Ank_5 PF13857.6 KXS12576.1 - 9.2e-10 38.6 0.8 0.0058 16.9 0.0 4.7 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 KXS12576.1 - 4e-09 36.5 0.7 0.31 11.6 0.1 6.1 8 0 0 8 8 8 2 Ankyrin repeat Lipase_GDSL PF00657.22 KXS12578.1 - 3.8e-10 40.1 0.0 9.5e-10 38.8 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 KXS12578.1 - 0.0019 18.6 0.0 0.091 13.2 0.0 2.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family MT-A70 PF05063.14 KXS12579.1 - 7.3e-31 107.4 0.0 8.5e-31 107.2 0.0 1.0 1 0 0 1 1 1 1 MT-A70 Phytase-like PF13449.6 KXS12580.1 - 7.5e-53 180.3 0.0 9.3e-53 180.0 0.0 1.1 1 0 0 1 1 1 1 Esterase-like activity of phytase Glyco_transf_90 PF05686.12 KXS12581.1 - 1.7e-16 60.2 0.0 8.7e-16 57.8 0.0 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.6 KXS12581.1 - 0.048 14.1 0.0 0.085 13.3 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferases group 1 DUF2154 PF09922.9 KXS12583.1 - 6e-06 26.1 0.4 4.1e-05 23.4 0.0 2.0 1 1 1 2 2 2 1 Cell wall-active antibiotics response 4TMS YvqF DUF2977 PF11192.8 KXS12583.1 - 1.1 9.4 2.9 74 3.6 0.0 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF2977) Put_Phosphatase PF06888.12 KXS12584.1 - 1.3e-42 145.8 0.0 2.8e-24 85.8 0.0 2.0 2 0 0 2 2 2 2 Putative Phosphatase HAD PF12710.7 KXS12584.1 - 4.6e-06 27.1 2.3 6.6e-05 23.4 1.0 2.6 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KXS12584.1 - 0.13 12.6 0.0 1.1 9.5 0.0 2.2 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Phg_2220_C PF09524.10 KXS12584.1 - 0.26 11.4 0.8 0.74 9.9 0.2 1.9 2 0 0 2 2 2 0 Conserved phage C-terminus (Phg_2220_C) Trypsin PF00089.26 KXS12585.1 - 2.8e-30 105.8 5.0 3.2e-30 105.6 5.0 1.0 1 0 0 1 1 1 1 Trypsin Aldedh PF00171.22 KXS12586.1 - 2.2e-168 560.5 0.3 2.5e-168 560.4 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family AAA PF00004.29 KXS12587.1 - 2.2e-42 144.6 0.0 3.9e-42 143.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KXS12587.1 - 1.2e-10 41.1 0.0 2.6e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 KXS12587.1 - 7.9e-09 35.2 1.0 1.4e-08 34.4 1.0 1.4 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 KXS12587.1 - 4.1e-06 27.0 0.0 8.1e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 KXS12587.1 - 3.3e-05 23.2 0.0 6.2e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 KXS12587.1 - 3.9e-05 23.9 0.2 0.028 14.7 0.1 2.4 1 1 1 2 2 2 2 AAA domain AAA_5 PF07728.14 KXS12587.1 - 8.1e-05 22.6 0.1 0.0005 20.1 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KXS12587.1 - 0.0002 21.8 0.1 0.0072 16.7 0.1 2.4 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 KXS12587.1 - 0.00054 19.7 0.0 0.001 18.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 KXS12587.1 - 0.0029 18.1 0.1 0.0069 16.9 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_33 PF13671.6 KXS12587.1 - 0.0064 16.7 0.0 0.014 15.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 KXS12587.1 - 0.0068 15.8 0.1 0.2 11.0 0.1 2.4 1 1 1 2 2 2 1 KaiC AAA_3 PF07726.11 KXS12587.1 - 0.0074 16.1 0.1 0.022 14.6 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 KXS12587.1 - 0.02 14.9 0.0 0.039 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KXS12587.1 - 0.028 14.2 0.0 0.053 13.2 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_28 PF13521.6 KXS12587.1 - 0.039 14.2 0.3 0.1 12.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain Prot_ATP_OB_N PF17758.1 KXS12587.1 - 0.084 12.5 0.2 1 9.0 0.0 2.6 3 0 0 3 3 2 0 Proteasomal ATPase OB N-terminal domain TIP49 PF06068.13 KXS12587.1 - 0.084 12.1 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain NACHT PF05729.12 KXS12587.1 - 0.089 12.7 0.1 0.82 9.6 0.1 2.1 1 1 1 2 2 2 0 NACHT domain DUF2075 PF09848.9 KXS12587.1 - 0.11 11.7 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.22 KXS12587.1 - 0.11 12.9 0.0 0.22 11.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.21 KXS12587.1 - 0.13 11.6 0.0 0.26 10.7 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 KXS12587.1 - 0.14 11.8 0.3 0.35 10.5 0.3 1.7 1 1 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 KXS12587.1 - 0.16 11.7 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 KXS12587.1 - 0.19 11.4 0.4 0.42 10.3 0.4 1.6 1 1 0 1 1 1 0 AAA domain CCDC85 PF10226.9 KXS12588.1 - 0.00028 20.6 2.3 0.00036 20.3 2.3 1.1 1 0 0 1 1 1 1 CCDC85 family CCDC23 PF15674.5 KXS12588.1 - 0.0025 17.7 4.0 0.0049 16.8 4.0 1.5 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 23 TMCO5 PF14992.6 KXS12588.1 - 0.0061 16.2 1.4 0.008 15.8 1.4 1.2 1 0 0 1 1 1 1 TMCO5 family bZIP_1 PF00170.21 KXS12588.1 - 0.019 15.0 15.0 0.051 13.7 15.0 1.6 1 1 0 1 1 1 0 bZIP transcription factor GAS PF13851.6 KXS12588.1 - 0.21 10.9 6.7 0.29 10.4 6.7 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding YabA PF06156.13 KXS12588.1 - 0.37 11.5 2.3 0.43 11.2 1.6 1.4 1 1 0 1 1 1 0 Initiation control protein YabA bZIP_2 PF07716.15 KXS12588.1 - 4 7.6 15.8 42 4.3 15.8 2.1 1 1 0 1 1 1 0 Basic region leucine zipper Nodulin_late PF07127.11 KXS12589.1 - 0.065 13.6 0.0 0.097 13.0 0.0 1.3 1 0 0 1 1 1 0 Late nodulin protein DUF900 PF05990.12 KXS12590.1 - 9.8e-12 44.9 0.0 1.3e-10 41.2 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_6 PF12697.7 KXS12590.1 - 0.00097 19.8 0.1 0.0012 19.5 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXS12590.1 - 0.013 15.2 0.0 0.019 14.6 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold AMP-binding_C PF13193.6 KXS12591.1 - 0.074 14.0 0.0 0.12 13.4 0.0 1.3 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain LCM PF04072.14 KXS12592.1 - 6.7e-09 36.0 0.0 3.8e-08 33.5 0.0 2.0 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase DUF938 PF06080.12 KXS12592.1 - 0.079 12.7 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF938) CK_II_beta PF01214.18 KXS12593.1 - 2e-65 220.0 0.0 2.8e-65 219.6 0.0 1.2 1 0 0 1 1 1 1 Casein kinase II regulatory subunit BUD22 PF09073.10 KXS12593.1 - 0.028 13.8 8.5 0.04 13.3 8.5 1.3 1 0 0 1 1 1 0 BUD22 Mu-like_Com PF10122.9 KXS12593.1 - 0.17 11.4 0.4 1.1 8.8 0.4 2.3 1 1 0 1 1 1 0 Mu-like prophage protein Com Acyl-CoA_dh_1 PF00441.24 KXS12594.1 - 1.8e-38 132.1 0.6 3.9e-38 131.0 0.6 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KXS12594.1 - 7e-22 77.5 0.3 1.2e-21 76.7 0.3 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.28 KXS12594.1 - 3.5e-20 71.9 0.0 9.3e-20 70.6 0.0 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.16 KXS12594.1 - 2.1e-12 47.7 0.0 4.6e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KXS12594.1 - 2e-05 24.9 0.0 4.2e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain S4 PF01479.25 KXS12595.1 - 1.3e-12 47.2 0.0 3.1e-12 46.0 0.0 1.7 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.19 KXS12595.1 - 3.5e-09 37.5 0.6 6.4e-09 36.6 0.5 1.6 2 0 0 2 2 2 1 Ribosomal protein S4/S9 N-terminal domain Form_Nir_trans PF01226.17 KXS12596.1 - 2.9e-62 210.1 22.8 3.2e-62 210.0 22.8 1.0 1 0 0 1 1 1 1 Formate/nitrite transporter HA2 PF04408.23 KXS12597.1 - 1.8e-19 70.0 0.0 1e-18 67.6 0.0 2.3 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KXS12597.1 - 5.9e-16 58.8 0.0 1.5e-15 57.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KXS12597.1 - 6.8e-12 45.5 0.0 1.6e-11 44.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KXS12597.1 - 2.2e-06 28.0 0.0 5.6e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain OB_NTP_bind PF07717.16 KXS12597.1 - 0.0085 16.4 0.0 0.019 15.3 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold IstB_IS21 PF01695.17 KXS12597.1 - 0.014 15.1 0.0 4.9 6.8 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein Rad17 PF03215.15 KXS12597.1 - 0.017 15.0 0.2 0.037 14.0 0.0 1.5 2 0 0 2 2 2 0 Rad17 P-loop domain T2SSE PF00437.20 KXS12597.1 - 0.021 13.9 0.0 0.044 12.8 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_19 PF13245.6 KXS12597.1 - 0.024 14.9 0.0 0.051 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KXS12597.1 - 0.075 13.5 0.0 0.38 11.3 0.0 2.2 2 0 0 2 2 2 0 ABC transporter Myb_Cef PF11831.8 KXS12598.1 - 8.6e-34 117.1 0.0 8.6e-34 117.1 0.0 3.9 4 1 0 4 4 4 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.31 KXS12598.1 - 1.2e-22 79.8 4.0 1.1e-11 44.7 1.2 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KXS12598.1 - 2.6e-20 72.4 5.0 2.8e-13 49.9 2.5 2.7 1 1 1 2 2 2 2 Myb-like DNA-binding domain Glyco_hydro_26 PF02156.15 KXS12599.1 - 7.9e-10 38.6 0.2 2.3e-05 24.0 0.0 2.3 2 0 0 2 2 2 2 Glycosyl hydrolase family 26 EF-hand_5 PF13202.6 KXS12599.1 - 0.037 13.5 0.2 0.078 12.5 0.2 1.4 1 0 0 1 1 1 0 EF hand DUF1054 PF06335.12 KXS12600.1 - 0.029 14.3 0.3 0.035 14.0 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1054) Cullin PF00888.22 KXS12601.1 - 4.6e-190 633.3 8.4 6.2e-190 632.9 8.4 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KXS12601.1 - 2.5e-27 94.7 1.2 2.5e-27 94.7 1.2 2.0 2 0 0 2 2 2 1 Cullin protein neddylation domain CsgA PF17334.2 KXS12601.1 - 0.05 14.3 6.0 6.5 7.6 0.2 4.1 4 0 0 4 4 4 0 Minor curli fiber component A Phage_TAC_12 PF12363.8 KXS12601.1 - 0.066 13.6 0.2 0.44 11.0 0.2 2.5 1 1 0 1 1 1 0 Phage tail assembly chaperone protein, TAC OrfB_IS605 PF01385.19 KXS12601.1 - 0.086 13.1 0.9 0.21 11.8 0.0 2.1 2 0 0 2 2 2 0 Probable transposase Penicillinase_R PF03965.16 KXS12601.1 - 2 8.8 9.4 2.7 8.4 0.1 4.4 5 0 0 5 5 5 0 Penicillinase repressor NIF PF03031.18 KXS12602.1 - 1.2e-40 138.8 0.1 1.8e-40 138.3 0.1 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase hDGE_amylase PF14701.6 KXS12602.1 - 0.09 11.8 0.0 0.11 11.5 0.0 1.1 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain Selenoprotein_S PF06936.11 KXS12602.1 - 4.3 7.1 9.7 0.14 12.0 2.2 1.9 2 0 0 2 2 2 0 Selenoprotein S (SelS) Med8 PF10232.9 KXS12604.1 - 4.3e-06 26.5 8.1 3.6e-05 23.5 8.0 2.1 1 1 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 CO_deh_flav_C PF03450.17 KXS12604.1 - 0.043 14.0 0.1 0.078 13.2 0.1 1.4 1 0 0 1 1 1 0 CO dehydrogenase flavoprotein C-terminal domain Fcf2 PF08698.11 KXS12605.1 - 3.5e-35 120.3 1.4 3.5e-35 120.3 1.4 2.1 2 0 0 2 2 2 1 Fcf2 pre-rRNA processing DUF4637 PF15470.6 KXS12605.1 - 0.41 10.4 4.3 0.5 10.1 3.3 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) Dala_Dala_lig_C PF07478.13 KXS12607.1 - 2.3e-12 46.9 0.0 4e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_4 PF13535.6 KXS12607.1 - 0.013 15.1 0.0 0.044 13.4 0.0 1.9 2 0 0 2 2 2 0 ATP-grasp domain ATP-grasp_3 PF02655.14 KXS12607.1 - 0.019 15.0 0.0 0.054 13.5 0.0 1.8 1 1 0 1 1 1 0 ATP-grasp domain CPSase_L_D2 PF02786.17 KXS12607.1 - 0.088 12.3 0.0 0.24 10.9 0.0 1.6 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, ATP binding domain IlvN PF07991.12 KXS12608.1 - 3.7e-44 150.2 0.0 6e-44 149.5 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 KXS12608.1 - 7.4e-41 139.8 0.0 1.3e-40 139.0 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_2 PF03446.15 KXS12608.1 - 0.078 13.1 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase DUF3539 PF12058.8 KXS12608.1 - 0.13 12.4 0.1 0.28 11.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3539) PRIMA1 PF16101.5 KXS12609.1 - 0.47 10.5 2.5 1 9.4 1.2 2.1 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 DNA_repr_REX1B PF14966.6 KXS12610.1 - 5.7e-10 39.7 0.2 8e-09 36.1 0.0 2.0 2 0 0 2 2 2 1 DNA repair REX1-B HAUS-augmin3 PF14932.6 KXS12610.1 - 0.037 13.6 0.3 0.041 13.5 0.3 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 CdvA PF18822.1 KXS12610.1 - 0.11 12.3 0.5 8.3 6.3 0.5 2.2 1 1 0 1 1 1 0 CdvA-like coiled-coil domain GHL5 PF14872.6 KXS12610.1 - 0.13 10.2 0.1 0.15 10.0 0.1 1.1 1 0 0 1 1 1 0 Hypothetical glycoside hydrolase 5 CCDC53 PF10152.9 KXS12611.1 - 0.13 12.7 0.2 0.19 12.1 0.2 1.3 1 1 0 1 1 1 0 Subunit CCDC53 of WASH complex FAP206 PF12018.8 KXS12612.1 - 4.8e-53 180.5 0.0 8.9e-53 179.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function YHS PF04945.13 KXS12612.1 - 0.033 14.3 0.0 0.14 12.3 0.0 2.1 2 0 0 2 2 2 0 YHS domain ITAM_Cys-rich PF10538.9 KXS12612.1 - 0.041 13.6 0.3 0.081 12.7 0.3 1.4 1 0 0 1 1 1 0 Immunoreceptor tyrosine-based activation motif EI24 PF07264.11 KXS12613.1 - 1.1e-23 84.3 8.3 1.6e-23 83.9 8.3 1.2 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Methyltransf_16 PF10294.9 KXS12614.1 - 3.6e-29 101.7 0.1 7.7e-29 100.6 0.0 1.5 2 0 0 2 2 2 1 Lysine methyltransferase PrmA PF06325.13 KXS12614.1 - 0.00038 20.0 1.1 0.00052 19.5 1.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KXS12614.1 - 0.0012 18.4 0.1 0.0017 17.9 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 KXS12614.1 - 0.0022 18.7 0.1 0.0033 18.1 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 KXS12614.1 - 0.0052 16.4 0.1 0.0078 15.9 0.1 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_23 PF13489.6 KXS12614.1 - 0.014 15.3 0.0 0.018 14.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain GCV_H PF01597.19 KXS12614.1 - 0.1 12.5 0.2 0.64 9.9 0.1 2.1 2 0 0 2 2 2 0 Glycine cleavage H-protein GidB PF02527.15 KXS12614.1 - 0.14 11.5 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Sld5 PF05916.11 KXS12615.1 - 1.9e-10 41.2 0.0 2.6e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein Gluconate_2-dh3 PF13618.6 KXS12615.1 - 0.072 13.3 0.0 0.09 13.0 0.0 1.3 1 0 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 Mito_carr PF00153.27 KXS12616.1 - 9.3e-61 201.8 7.1 1.2e-22 79.6 0.1 4.3 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KXS12616.1 - 0.015 14.5 0.0 2.8 7.0 0.0 2.6 2 0 0 2 2 2 0 Gammaproteobacterial serine protease Acyl-CoA_dh_1 PF00441.24 KXS12618.1 - 8.5e-38 129.9 0.4 1.3e-37 129.3 0.4 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KXS12618.1 - 1.6e-21 76.3 0.5 2.8e-21 75.5 0.5 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.28 KXS12618.1 - 5.5e-21 74.5 0.0 1.2e-20 73.5 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.16 KXS12618.1 - 1.3e-09 38.7 0.0 6.5e-09 36.4 0.0 2.3 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KXS12618.1 - 3.4e-09 37.1 0.3 6.5e-09 36.2 0.3 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain NmrA PF05368.13 KXS12619.1 - 2.8e-12 46.7 0.0 3.7e-12 46.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXS12619.1 - 6.3e-09 36.0 0.0 8.9e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding DapB_N PF01113.20 KXS12619.1 - 0.00088 19.4 0.0 0.0013 18.8 0.0 1.3 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.24 KXS12619.1 - 0.0072 16.8 0.0 0.012 16.0 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KXS12619.1 - 0.018 15.1 0.0 0.026 14.6 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase GFO_IDH_MocA PF01408.22 KXS12619.1 - 0.069 14.0 0.0 0.12 13.2 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold CoA_binding PF02629.19 KXS12619.1 - 0.11 13.1 0.2 0.28 11.9 0.1 1.7 2 0 0 2 2 2 0 CoA binding domain Orai-1 PF07856.12 KXS12620.1 - 0.018 14.7 3.5 0.044 13.5 2.4 1.9 1 1 1 2 2 2 0 Mediator of CRAC channel activity DUF267 PF03268.14 KXS12620.1 - 0.057 12.3 0.1 0.1 11.5 0.0 1.4 1 1 0 1 1 1 0 Caenorhabditis protein of unknown function, DUF267 WD40 PF00400.32 KXS12621.1 - 2.2e-14 53.6 12.1 0.00025 21.8 0.0 7.1 7 0 0 7 7 6 3 WD domain, G-beta repeat zf-C3HC4_2 PF13923.6 KXS12621.1 - 4.4e-11 42.4 10.9 9.1e-11 41.4 10.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXS12621.1 - 1.5e-08 34.3 10.9 3.1e-08 33.3 10.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KXS12621.1 - 1.8e-08 34.1 7.7 3.6e-08 33.1 7.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXS12621.1 - 1.3e-06 28.2 9.4 1.3e-06 28.2 9.4 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KXS12621.1 - 1.9e-06 27.8 4.5 1.9e-06 27.8 4.5 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 KXS12621.1 - 2.3e-06 27.8 10.3 2.3e-06 27.8 10.3 1.9 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.6 KXS12621.1 - 3.9e-06 26.9 9.7 8.9e-06 25.8 9.7 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 KXS12621.1 - 0.00096 18.9 3.8 0.0025 17.6 3.8 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.6 KXS12621.1 - 0.0024 17.7 2.0 0.005 16.7 2.0 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 KXS12621.1 - 0.0037 17.5 5.7 0.0037 17.5 5.7 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger domain WD40_like PF17005.5 KXS12621.1 - 0.0049 16.2 0.0 0.049 13.0 0.0 2.2 1 1 1 2 2 2 1 WD40-like domain Prok-RING_4 PF14447.6 KXS12621.1 - 0.012 15.4 8.8 0.012 15.4 8.8 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 U-box PF04564.15 KXS12621.1 - 0.038 14.2 0.0 0.12 12.5 0.0 1.9 1 0 0 1 1 1 0 U-box domain eIF2A PF08662.11 KXS12621.1 - 0.14 12.0 0.1 14 5.5 0.0 2.5 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Baculo_IE-1 PF05290.11 KXS12621.1 - 0.31 11.0 1.6 0.62 10.0 1.6 1.4 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-RING_10 PF16685.5 KXS12621.1 - 0.42 10.8 8.7 0.23 11.6 4.6 2.2 2 0 0 2 2 2 0 zinc RING finger of MSL2 zf-RING_4 PF14570.6 KXS12621.1 - 0.44 10.4 7.8 0.97 9.3 7.8 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 KXS12621.1 - 0.54 10.3 3.7 0.77 9.9 1.7 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger HECT PF00632.25 KXS12622.1 - 4e-83 279.4 0.0 5.6e-83 279.0 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF2070 PF09843.9 KXS12623.1 - 0.12 10.7 8.8 0.15 10.3 8.8 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) TRIQK PF15168.6 KXS12623.1 - 0.16 11.9 6.8 0.4 10.6 1.8 2.6 2 0 0 2 2 2 0 Triple QxxK/R motif-containing protein family LysM PF01476.20 KXS12624.1 - 1e-05 25.5 0.1 1.5e-05 25.0 0.1 1.2 1 0 0 1 1 1 1 LysM domain Nop14 PF04147.12 KXS12624.1 - 0.0023 16.2 58.9 0.0031 15.8 58.9 1.3 1 0 0 1 1 1 1 Nop14-like family TFIIF_alpha PF05793.12 KXS12624.1 - 0.014 14.0 59.4 0.022 13.4 59.4 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Caldesmon PF02029.15 KXS12624.1 - 0.15 10.8 60.0 0.2 10.4 60.0 1.2 1 0 0 1 1 1 0 Caldesmon LTV PF04180.14 KXS12624.1 - 3.5 7.3 37.8 4.9 6.8 37.8 1.3 1 0 0 1 1 1 0 Low temperature viability protein Thioredoxin PF00085.20 KXS12625.1 - 6e-65 215.7 0.0 1.1e-31 108.9 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.12 KXS12625.1 - 4.1e-20 72.5 2.7 8.9e-20 71.4 2.7 1.6 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain OST3_OST6 PF04756.13 KXS12625.1 - 3.3e-13 49.7 0.0 1e-06 28.3 0.0 2.3 1 1 1 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 KXS12625.1 - 6.7e-12 45.8 0.9 2.4e-06 28.0 0.0 3.3 2 2 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KXS12625.1 - 2.4e-08 34.2 0.3 0.016 15.5 0.0 4.0 3 2 2 5 5 5 2 Thioredoxin-like Thioredoxin_7 PF13899.6 KXS12625.1 - 1.1e-07 31.9 0.0 0.0044 17.2 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.21 KXS12625.1 - 1.6e-07 31.3 0.1 0.0081 16.1 0.0 2.4 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_6 PF13848.6 KXS12625.1 - 1.6e-06 28.2 0.3 0.24 11.3 0.0 3.7 2 2 1 3 3 3 3 Thioredoxin-like domain HyaE PF07449.11 KXS12625.1 - 3.3e-05 23.8 0.0 0.053 13.5 0.0 2.7 2 0 0 2 2 2 2 Hydrogenase-1 expression protein HyaE Redoxin PF08534.10 KXS12625.1 - 0.00017 21.3 0.0 0.54 10.0 0.0 2.4 2 0 0 2 2 2 2 Redoxin TraF PF13728.6 KXS12625.1 - 0.00033 20.5 0.9 1 9.1 0.0 2.8 3 0 0 3 3 3 2 F plasmid transfer operon protein Thioredoxin_4 PF13462.6 KXS12625.1 - 0.0032 17.6 3.2 4.7 7.4 0.1 3.4 3 0 0 3 3 3 2 Thioredoxin DDE_Tnp_1_2 PF13586.6 KXS12625.1 - 0.0044 17.4 0.0 2 8.9 0.0 2.7 2 1 0 2 2 2 1 Transposase DDE domain Thioredoxin_9 PF14595.6 KXS12625.1 - 0.052 13.3 0.1 3.4 7.5 0.0 2.5 2 0 0 2 2 2 0 Thioredoxin LBP_BPI_CETP PF01273.25 KXS12626.1 - 0.00051 19.7 0.0 0.0058 16.3 0.0 2.3 1 1 0 1 1 1 1 LBP / BPI / CETP family, N-terminal domain Coatomer_E PF04733.14 KXS12627.1 - 1.8e-75 254.1 2.1 2e-75 253.9 2.1 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit ANAPC3 PF12895.7 KXS12627.1 - 8.5e-05 22.7 0.3 0.0022 18.2 0.1 2.7 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 KXS12627.1 - 0.012 16.1 12.5 0.076 13.5 0.1 4.6 2 1 3 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.6 KXS12627.1 - 0.025 14.8 6.2 0.87 9.9 0.0 4.1 2 2 1 4 4 4 0 Tetratricopeptide repeat ATP-synt_G PF04718.15 KXS12627.1 - 0.093 13.6 0.7 0.38 11.6 0.1 2.1 2 1 0 2 2 2 0 Mitochondrial ATP synthase g subunit ubiquitin PF00240.23 KXS12628.1 - 4.2e-18 64.8 0.1 6.4e-18 64.3 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 KXS12628.1 - 8.8e-11 41.5 0.1 2e-10 40.3 0.1 1.7 1 0 0 1 1 1 1 UBA/TS-N domain Rad60-SLD PF11976.8 KXS12628.1 - 2.1e-06 27.5 0.0 3.7e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like STI1 PF17830.1 KXS12628.1 - 4.3e-06 26.6 7.6 0.0037 17.2 0.3 2.6 1 1 1 2 2 2 2 STI1 domain DUF2407 PF10302.9 KXS12628.1 - 0.00058 20.4 0.0 0.0014 19.1 0.0 1.6 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 KXS12628.1 - 0.00069 19.7 0.0 0.0021 18.1 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like CUE PF02845.16 KXS12628.1 - 0.028 14.1 0.8 0.16 11.8 0.0 2.3 2 0 0 2 2 2 0 CUE domain HOIP-UBA PF16678.5 KXS12628.1 - 0.084 12.9 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 HOIP UBA domain pair Pkinase PF00069.25 KXS12629.1 - 3.7e-69 233.0 0.0 4.5e-69 232.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS12629.1 - 5.8e-39 133.9 0.0 7.4e-39 133.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXS12629.1 - 0.00065 18.6 0.0 0.0012 17.7 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KXS12629.1 - 0.00077 19.5 0.0 0.0013 18.7 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KXS12629.1 - 0.0043 16.4 0.0 0.0074 15.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 KXS12629.1 - 0.02 14.0 0.0 0.15 11.1 0.0 2.1 2 0 0 2 2 2 0 Seadornavirus VP7 IP_trans PF02121.18 KXS12629.1 - 0.041 13.4 0.0 5.2 6.6 0.0 2.1 2 0 0 2 2 2 0 Phosphatidylinositol transfer protein Haspin_kinase PF12330.8 KXS12629.1 - 0.042 12.8 0.1 0.12 11.3 0.0 1.6 2 0 0 2 2 2 0 Haspin like kinase domain TPR_2 PF07719.17 KXS12630.1 - 4.4e-05 23.3 2.2 0.88 9.8 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KXS12630.1 - 8e-05 22.3 0.2 2.1 8.3 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KXS12630.1 - 0.0004 20.8 1.9 0.032 14.7 0.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 KXS12630.1 - 0.00063 19.8 0.8 0.00063 19.8 0.8 3.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 KXS12630.1 - 0.0014 18.3 0.4 0.041 13.6 0.0 2.6 3 0 0 3 3 3 1 TPR repeat CS PF04969.16 KXS12630.1 - 0.038 15.0 0.0 0.077 14.0 0.0 1.6 1 0 0 1 1 1 0 CS domain Herpes_capsid PF06112.11 KXS12630.1 - 0.13 12.4 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein TPR_14 PF13428.6 KXS12630.1 - 0.32 11.9 22.7 0.092 13.6 3.0 4.6 4 1 1 5 5 5 0 Tetratricopeptide repeat Abhydrolase_1 PF00561.20 KXS12632.1 - 1.3e-21 77.4 0.1 9.4e-21 74.6 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXS12632.1 - 9e-21 75.5 0.2 1.5e-20 74.8 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXS12632.1 - 4.7e-11 42.4 0.0 6.5e-11 42.0 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 KXS12632.1 - 2.8e-09 37.0 0.0 6.1e-07 29.4 0.0 2.6 1 1 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.20 KXS12632.1 - 0.00015 21.9 0.0 0.00021 21.5 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Chlorophyllase2 PF12740.7 KXS12632.1 - 0.0033 16.4 0.0 0.0055 15.6 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme PAF-AH_p_II PF03403.13 KXS12632.1 - 0.047 12.2 0.0 1.6 7.2 0.0 2.7 2 1 1 3 3 3 0 Platelet-activating factor acetylhydrolase, isoform II Palm_thioest PF02089.15 KXS12632.1 - 0.056 13.3 0.0 0.085 12.7 0.0 1.3 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Esterase PF00756.20 KXS12632.1 - 0.067 12.8 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Chlorophyllase PF07224.11 KXS12632.1 - 0.067 12.2 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase DUF676 PF05057.14 KXS12632.1 - 0.079 12.5 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Ser_hydrolase PF06821.13 KXS12632.1 - 0.081 12.8 0.0 0.14 12.0 0.0 1.5 1 1 0 1 1 1 0 Serine hydrolase Abhydro_lipase PF04083.16 KXS12632.1 - 0.27 10.8 0.4 3.5 7.3 0.0 2.7 3 0 0 3 3 3 0 Partial alpha/beta-hydrolase lipase region CUE PF02845.16 KXS12633.1 - 9.8e-06 25.2 0.7 0.42 10.4 0.0 3.7 4 0 0 4 4 4 2 CUE domain IBR PF01485.21 KXS12633.1 - 3.6e-05 23.9 8.6 3.6e-05 23.9 8.6 5.0 3 1 2 5 5 5 2 IBR domain, a half RING-finger domain Peptidase_C48 PF02902.19 KXS12634.1 - 8.7e-26 91.1 0.2 6.6e-25 88.2 0.2 2.0 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Epimerase PF01370.21 KXS12635.1 - 2.4e-13 50.1 0.1 2.9e-12 46.6 0.1 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KXS12635.1 - 9.5e-13 48.4 0.0 1.4e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KXS12635.1 - 7.8e-10 38.7 0.0 1.1e-09 38.2 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.17 KXS12635.1 - 2.4e-08 33.4 0.1 8.5e-07 28.3 0.0 2.6 2 1 0 2 2 2 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 KXS12635.1 - 2.8e-06 26.5 0.0 0.0032 16.5 0.0 2.2 1 1 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KXS12635.1 - 4.4e-06 26.0 0.5 0.088 12.0 0.0 3.1 3 1 1 4 4 4 2 Male sterility protein GDP_Man_Dehyd PF16363.5 KXS12635.1 - 0.0093 15.4 0.1 1.5 8.1 0.0 2.4 2 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase Sacchrp_dh_NADP PF03435.18 KXS12635.1 - 0.065 13.5 0.0 0.17 12.2 0.0 1.7 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain FAD_SOX PF18371.1 KXS12635.1 - 0.16 12.4 0.0 0.3 11.5 0.0 1.4 1 0 0 1 1 1 0 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase Actin PF00022.19 KXS12636.1 - 1e-56 192.3 0.0 1.2e-30 106.4 0.0 2.5 2 1 0 2 2 2 2 Actin DUF3040 PF11239.8 KXS12636.1 - 0.27 11.5 5.7 0.42 10.9 1.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) Acyltransferase PF01553.21 KXS12637.1 - 2.5e-09 36.9 0.0 3.9e-08 33.0 0.0 2.3 1 1 0 1 1 1 1 Acyltransferase DAP10 PF07213.11 KXS12638.1 - 0.0026 17.7 0.2 0.0071 16.3 0.2 1.7 1 0 0 1 1 1 1 DAP10 membrane protein CEND1 PF15677.5 KXS12638.1 - 0.0066 17.0 2.1 0.02 15.5 2.1 1.8 1 0 0 1 1 1 1 Cell cycle exit and neuronal differentiation protein 1 DUF4690 PF15756.5 KXS12638.1 - 0.017 15.7 1.9 0.072 13.7 1.9 2.2 1 0 0 1 1 1 0 Small Novel Rich in Cartilage Amnionless PF14828.6 KXS12638.1 - 0.13 11.1 0.0 0.19 10.5 0.0 1.1 1 0 0 1 1 1 0 Amnionless Glyco_hydro_28 PF00295.17 KXS12639.1 - 1.3e-26 93.4 0.3 1.8e-26 93.0 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Pectate_lyase_3 PF12708.7 KXS12639.1 - 2.7e-09 37.2 6.6 1.3e-07 31.7 0.0 2.9 2 1 0 2 2 2 2 Pectate lyase superfamily protein Glyco_hydro_49 PF03718.13 KXS12639.1 - 0.12 12.3 1.4 3.5 7.6 0.6 2.4 2 0 0 2 2 2 0 Glycosyl hydrolase family 49 Exo_endo_phos PF03372.23 KXS12640.1 - 0.00031 20.3 2.0 0.00042 19.9 2.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family FSA_C PF10479.9 KXS12643.1 - 2.5 6.1 5.2 3.4 5.7 5.2 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus 2-Hacid_dh_C PF02826.19 KXS12645.1 - 1.5e-40 138.5 0.0 2.1e-40 138.0 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KXS12645.1 - 0.019 14.6 0.0 0.025 14.3 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KXS12645.1 - 0.033 14.4 0.0 0.049 13.8 0.0 1.2 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase PROCN PF08083.11 KXS12646.1 - 6.2e-233 772.8 6.0 1.1e-232 772.0 6.0 1.4 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 KXS12646.1 - 7.5e-128 424.9 0.2 1.3e-127 424.2 0.2 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 KXS12646.1 - 2.9e-89 297.1 3.0 7.3e-89 295.8 3.0 1.8 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 KXS12646.1 - 5.6e-85 282.9 4.5 1.4e-84 281.6 4.5 1.7 1 0 0 1 1 1 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 KXS12646.1 - 2.1e-74 248.0 0.0 4.2e-74 247.0 0.0 1.5 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.9 KXS12646.1 - 2e-46 156.2 0.4 4.9e-46 155.0 0.4 1.7 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.11 KXS12646.1 - 2e-45 153.7 0.0 6.2e-45 152.1 0.0 1.8 1 0 0 1 1 1 1 PROCT (NUC072) domain JAB PF01398.21 KXS12646.1 - 2.4e-08 34.0 0.0 5.7e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease zf-C2H2 PF00096.26 KXS12647.1 - 8e-30 101.6 47.9 2.6e-05 24.4 1.1 8.3 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXS12647.1 - 1.2e-22 78.6 46.6 0.00029 21.4 0.1 8.2 8 0 0 8 8 8 7 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KXS12647.1 - 2.1e-11 43.7 40.1 0.0014 18.9 1.1 8.3 8 0 0 8 8 8 5 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KXS12647.1 - 3e-11 43.3 0.5 0.64 10.4 0.2 6.2 6 0 0 6 6 6 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KXS12647.1 - 1.6e-07 31.5 14.3 4.5 7.8 0.0 6.5 6 0 0 6 6 6 2 Zinc-finger of C2H2 type zf-Di19 PF05605.12 KXS12647.1 - 3.3e-06 27.3 27.6 0.0023 18.2 0.5 5.6 5 0 0 5 5 5 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_3rep PF18868.1 KXS12647.1 - 3.2e-05 24.6 9.2 3.2 8.5 0.4 5.1 3 1 2 5 5 5 2 Zinc finger C2H2-type, 3 repeats Zn-C2H2_12 PF18112.1 KXS12647.1 - 0.00089 19.7 9.1 0.11 13.0 0.2 5.6 5 0 0 5 5 5 1 Autophagy receptor zinc finger-C2H2 domain zf-C2H2_6 PF13912.6 KXS12647.1 - 0.0014 18.5 24.4 0.5 10.4 0.2 6.7 6 1 0 6 6 6 2 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KXS12647.1 - 0.0048 17.2 15.4 0.11 12.8 1.3 4.0 3 1 1 4 4 4 2 C2H2-type zinc ribbon zf-C2H2_2 PF12756.7 KXS12647.1 - 0.011 16.0 15.2 4.4 7.7 0.2 5.2 3 1 2 5 5 5 0 C2H2 type zinc-finger (2 copies) zinc_ribbon_4 PF13717.6 KXS12647.1 - 0.069 13.1 13.0 15 5.6 0.1 4.9 5 0 0 5 5 5 0 zinc-ribbon domain zf-C2H2_11 PF16622.5 KXS12647.1 - 0.13 12.0 26.9 0.25 11.1 0.3 6.0 6 0 0 6 6 6 0 zinc-finger C2H2-type Serglycin PF04360.12 KXS12647.1 - 0.14 12.1 1.2 0.32 10.9 1.2 1.5 1 0 0 1 1 1 0 Serglycin IBR PF01485.21 KXS12647.1 - 0.21 11.8 11.1 1 9.6 0.6 4.0 4 0 0 4 4 4 0 IBR domain, a half RING-finger domain zf_Hakai PF18408.1 KXS12647.1 - 1.2 8.9 0.0 1.2 8.9 0.0 3.3 3 0 0 3 3 2 0 C2H2 Hakai zinc finger domain Elf1 PF05129.13 KXS12647.1 - 1.3 9.1 8.7 24 5.0 0.1 4.2 4 0 0 4 4 4 0 Transcription elongation factor Elf1 like CpXC PF14353.6 KXS12647.1 - 2 8.5 10.7 24 5.0 1.1 4.3 3 1 2 5 5 5 0 CpXC protein zf-C2H2_9 PF16293.5 KXS12647.1 - 2.1 8.2 15.9 8.8 6.3 0.0 5.2 5 1 1 6 6 5 0 C2H2 type zinc-finger (1 copy) DUF2225 PF09986.9 KXS12647.1 - 2.3 7.9 6.0 49 3.5 0.1 3.8 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2225) DUF2256 PF10013.9 KXS12647.1 - 8.5 6.6 22.1 25 5.1 0.1 5.7 6 0 0 6 6 6 0 Uncharacterized protein conserved in bacteria (DUF2256) DUF2306 PF10067.9 KXS12648.1 - 6.6e-06 26.4 1.1 8.6e-06 26.0 1.1 1.3 1 0 0 1 1 1 1 Predicted membrane protein (DUF2306) Chitin_synth_2 PF03142.15 KXS12649.1 - 4e-194 646.1 0.2 4.5e-194 645.9 0.2 1.0 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.6 KXS12649.1 - 1.7e-14 54.2 3.4 3.3e-14 53.3 3.4 1.5 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KXS12649.1 - 2e-10 40.9 0.0 3.3e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KXS12649.1 - 0.00024 20.6 0.3 0.029 13.9 0.2 2.6 2 1 1 3 3 3 2 Glycosyl transferase family 21 Reeler PF02014.16 KXS12651.1 - 3.3e-07 31.1 0.7 5.8e-07 30.3 0.0 1.7 2 0 0 2 2 2 1 Reeler domain MMR_HSR1 PF01926.23 KXS12652.1 - 1.8e-17 63.4 0.0 4e-15 55.9 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 KXS12652.1 - 5.2e-08 32.6 0.0 3.8e-06 26.5 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KXS12652.1 - 1.3e-07 31.7 0.0 0.00027 20.9 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AIG1 PF04548.16 KXS12652.1 - 0.00012 21.4 0.0 0.00024 20.5 0.0 1.5 1 0 0 1 1 1 1 AIG1 family GTP_EFTU PF00009.27 KXS12652.1 - 0.00025 20.7 0.0 0.64 9.5 0.0 2.4 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 KXS12652.1 - 0.012 15.7 0.4 0.012 15.7 0.4 2.9 2 1 1 3 3 3 0 Dynamin family Roc PF08477.13 KXS12652.1 - 0.075 13.3 0.3 1.7 8.9 0.0 2.5 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 KXS12652.1 - 0.25 11.9 0.5 0.6 10.6 0.1 1.8 2 0 0 2 2 2 0 ABC transporter ASH PF15780.5 KXS12653.1 - 1.3e-08 34.9 1.1 0.28 11.4 0.0 6.5 8 0 0 8 8 8 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 KXS12653.1 - 0.0014 18.4 0.8 5.7 6.8 0.0 5.3 6 0 0 6 6 6 1 MSP (Major sperm protein) domain PapD-like PF14874.6 KXS12653.1 - 0.016 15.3 0.9 2.6 8.3 0.1 3.2 3 0 0 3 3 3 0 Flagellar-associated PapD-like MYCBPAP PF14646.6 KXS12653.1 - 0.071 12.0 0.0 0.2 10.6 0.0 1.7 2 0 0 2 2 2 0 MYCBP-associated protein family Bap31 PF05529.12 KXS12654.1 - 5.9e-31 107.1 0.4 5.9e-31 107.1 0.4 1.8 2 0 0 2 2 2 1 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 KXS12654.1 - 2.5e-14 53.0 13.8 3e-12 46.3 8.4 2.4 1 1 1 2 2 2 2 Bap31/Bap29 cytoplasmic coiled-coil domain Fmp27_WPPW PF10359.9 KXS12654.1 - 0.035 13.0 6.0 0.046 12.6 6.0 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Agglutinin PF07468.11 KXS12654.1 - 0.039 14.2 0.1 0.059 13.6 0.1 1.3 1 0 0 1 1 1 0 Agglutinin domain kleA_kleC PF17383.2 KXS12654.1 - 0.17 12.2 1.2 0.37 11.1 0.5 1.8 1 1 1 2 2 2 0 Uncharacterized KorC regulated protein A FlaC_arch PF05377.11 KXS12654.1 - 0.22 11.9 0.2 0.22 11.9 0.2 1.9 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Ribosomal_S17 PF00366.20 KXS12655.1 - 1.4e-22 79.5 1.3 2.1e-22 79.0 1.3 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 Prenyltrans PF00432.21 KXS12656.1 - 3.4e-17 61.9 15.8 4.5e-05 23.1 0.2 6.2 7 0 0 7 7 7 4 Prenyltransferase and squalene oxidase repeat RICTOR_N PF14664.6 KXS12656.1 - 0.17 10.8 0.0 0.66 8.9 0.0 1.8 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, N-term Met_asp_mut_E PF06368.11 KXS12656.1 - 0.24 9.8 0.0 0.33 9.4 0.0 1.1 1 0 0 1 1 1 0 Methylaspartate mutase E chain (MutE) Myosin_head PF00063.21 KXS12657.1 - 8.9e-238 790.9 0.0 1.1e-237 790.6 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 KXS12657.1 - 9.8e-41 139.5 2.0 1.9e-40 138.6 2.0 1.5 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding SH3_9 PF14604.6 KXS12657.1 - 1.5e-15 56.8 0.1 3.4e-15 55.6 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXS12657.1 - 5.6e-15 54.7 0.0 1.3e-14 53.5 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KXS12657.1 - 2e-06 27.4 0.0 4.4e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain AAA_16 PF13191.6 KXS12657.1 - 0.006 17.0 0.0 0.016 15.6 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 KXS12657.1 - 0.014 15.3 0.0 0.037 13.9 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase AAA_22 PF13401.6 KXS12657.1 - 0.029 14.7 0.1 0.11 12.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain IQ PF00612.27 KXS12657.1 - 0.068 13.0 2.2 0.19 11.6 2.2 1.7 1 0 0 1 1 1 0 IQ calmodulin-binding motif DUF1744 PF08490.12 KXS12658.1 - 5.1e-130 433.7 1.3 7.7e-130 433.1 1.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 KXS12658.1 - 4.6e-74 249.5 0.0 1.6e-73 247.8 0.0 1.8 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 KXS12658.1 - 8.4e-15 54.4 0.4 2.3e-12 46.4 0.0 2.9 3 1 0 3 3 3 2 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 KXS12658.1 - 5e-06 26.4 0.0 1.7e-05 24.6 0.0 1.9 1 1 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 KXS12658.1 - 0.0012 18.8 0.0 0.0053 16.8 0.0 2.1 2 0 0 2 2 2 1 RNase_H superfamily zf-C2H2_3 PF13878.6 KXS12658.1 - 0.024 14.4 0.0 0.024 14.4 0.0 2.5 3 0 0 3 3 3 0 zinc-finger of acetyl-transferase ESCO SWIRM PF04433.17 KXS12659.1 - 5.7e-32 109.9 0.1 1.2e-31 108.8 0.1 1.6 1 0 0 1 1 1 1 SWIRM domain SWIRM-assoc_1 PF16495.5 KXS12659.1 - 3.1e-25 87.9 15.7 3.1e-25 87.9 15.7 2.2 3 0 0 3 3 3 1 SWIRM-associated region 1 Myb_DNA-binding PF00249.31 KXS12659.1 - 1.8e-13 50.4 0.1 3.8e-13 49.4 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KXS12659.1 - 1.5e-07 31.5 0.1 3.5e-07 30.4 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.17 KXS12659.1 - 2.8e-06 27.0 6.4 4.9e-06 26.3 6.4 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-bind_7 PF15963.5 KXS12659.1 - 0.1 12.5 1.3 1.3 9.0 0.0 2.4 2 0 0 2 2 2 0 Myb DNA-binding like NUC PF18510.1 KXS12659.1 - 0.21 12.0 0.4 0.4 11.1 0.4 1.4 1 0 0 1 1 1 0 Nuclease domain C1_2 PF03107.16 KXS12659.1 - 0.44 10.9 5.4 0.76 10.1 5.4 1.4 1 0 0 1 1 1 0 C1 domain RNase_PH PF01138.21 KXS12660.1 - 1.7e-23 83.6 0.1 5.4e-23 81.9 0.0 1.8 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KXS12660.1 - 5.5e-14 51.9 0.0 1.2e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Pns11_12 PF17464.2 KXS12660.1 - 0.0068 16.1 0.0 0.0092 15.7 0.0 1.2 1 0 0 1 1 1 1 Non-structural protein 11 and 12 UCR_UQCRX_QCR9 PF05365.12 KXS12661.1 - 7.3e-25 86.7 0.9 7.9e-25 86.6 0.9 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like RhoGAP PF00620.27 KXS12662.1 - 3.1e-32 111.5 0.0 1.6e-31 109.2 0.0 2.0 2 0 0 2 2 2 1 RhoGAP domain MyTH4 PF00784.17 KXS12662.1 - 4.1e-26 91.6 0.0 8.3e-25 87.4 0.0 2.3 2 0 0 2 2 2 1 MyTH4 domain WW PF00397.26 KXS12662.1 - 1.4e-05 25.1 6.0 0.047 13.8 0.0 2.4 2 0 0 2 2 2 2 WW domain Pkinase PF00069.25 KXS12663.1 - 1.6e-66 224.4 0.0 2e-66 224.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS12663.1 - 6.3e-34 117.4 0.0 9.1e-34 116.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KXS12663.1 - 7.6e-05 22.2 0.0 0.00024 20.5 0.0 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KXS12663.1 - 8.2e-05 21.7 0.0 0.00011 21.2 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KXS12663.1 - 0.0078 15.6 0.0 0.011 15.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KXS12663.1 - 0.01 15.8 0.0 0.022 14.7 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 KXS12663.1 - 0.015 15.0 0.0 0.022 14.4 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 KXS12663.1 - 0.015 14.9 0.1 0.038 13.6 0.0 1.7 2 0 0 2 2 2 0 RIO1 family eIF-6 PF01912.18 KXS12664.1 - 3.8e-80 267.9 0.4 3.8e-80 267.9 0.4 1.3 2 0 0 2 2 2 1 eIF-6 family G-alpha PF00503.20 KXS12665.1 - 1.2e-111 373.4 1.0 1.4e-111 373.1 1.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KXS12665.1 - 2.5e-16 59.6 4.2 2.3e-11 43.5 0.2 2.8 2 2 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KXS12665.1 - 1.9e-05 24.2 1.0 0.046 13.1 0.1 2.2 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 KXS12665.1 - 0.00033 20.8 0.4 0.28 11.4 0.1 2.6 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_15 PF13175.6 KXS12665.1 - 0.035 13.8 0.1 0.078 12.7 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain GTP_EFTU PF00009.27 KXS12665.1 - 0.043 13.4 0.0 1.1 8.8 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_29 PF13555.6 KXS12665.1 - 0.056 13.2 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Saw1 PF11561.8 KXS12665.1 - 0.07 12.7 1.0 0.12 11.9 1.0 1.3 1 0 0 1 1 1 0 Single strand annealing-weakened 1 Ank_2 PF12796.7 KXS12666.1 - 4e-08 33.7 0.2 7.1e-08 32.9 0.2 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXS12666.1 - 7.7e-08 32.7 0.1 2.7e-06 27.8 0.0 2.5 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KXS12666.1 - 9.3e-06 25.9 2.3 0.17 12.4 0.1 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 KXS12666.1 - 0.00035 20.8 0.3 3.2 8.6 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 KXS12666.1 - 0.00041 20.6 0.1 0.0019 18.5 0.1 2.1 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Mcl1_mid PF12341.8 KXS12667.1 - 1.7e-93 313.3 0.7 2.2e-92 309.6 0.0 2.8 3 1 0 3 3 3 1 Minichromosome loss protein, Mcl1, middle region WD40 PF00400.32 KXS12667.1 - 2e-13 50.6 25.9 3.8e-08 33.9 0.2 7.1 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXS12667.1 - 4e-09 36.7 1.3 0.045 14.1 0.0 4.9 1 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain DNA_pol_alpha_N PF12254.8 KXS12667.1 - 0.14 12.2 6.4 0.36 11.0 6.4 1.7 1 0 0 1 1 1 0 DNA polymerase alpha subunit p180 N terminal OB_NTP_bind PF07717.16 KXS12668.1 - 4.8e-19 68.5 0.0 1.4e-18 67.0 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 KXS12668.1 - 1.3e-18 67.2 0.0 3.3e-18 66.0 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KXS12668.1 - 4.8e-14 52.6 0.0 1.3e-13 51.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KXS12668.1 - 1.1e-07 31.8 0.4 4.5e-07 29.8 0.1 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KXS12668.1 - 6e-07 29.8 0.2 1.7e-06 28.4 0.1 1.8 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KXS12668.1 - 6.2e-06 26.1 0.1 1.2e-05 25.2 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KXS12668.1 - 2.8e-05 24.5 0.3 6.6e-05 23.3 0.3 1.5 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 KXS12668.1 - 0.0017 17.5 0.0 0.0044 16.1 0.0 1.7 1 0 0 1 1 1 1 Type II/IV secretion system protein SRP54 PF00448.22 KXS12668.1 - 0.021 14.5 1.4 0.063 12.9 1.4 1.9 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_7 PF12775.7 KXS12668.1 - 0.027 14.0 0.0 0.058 12.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Zeta_toxin PF06414.12 KXS12668.1 - 0.032 13.5 0.1 0.086 12.1 0.0 1.7 1 1 0 1 1 1 0 Zeta toxin cobW PF02492.19 KXS12668.1 - 0.12 12.0 0.0 3.9 7.0 0.0 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 KXS12668.1 - 0.12 12.5 0.6 0.72 10.0 0.6 2.3 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KXS12668.1 - 0.13 12.7 0.2 1.1 9.7 0.2 2.3 1 1 0 1 1 1 0 ABC transporter DUF2075 PF09848.9 KXS12668.1 - 0.14 11.4 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_14 PF13173.6 KXS12668.1 - 0.16 12.0 0.2 8.2 6.5 0.2 2.5 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 KXS12668.1 - 0.2 12.1 0.5 4 7.9 0.5 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Rad1 PF02144.16 KXS12669.1 - 3.9e-55 186.8 0.1 4.9e-55 186.5 0.1 1.1 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 PIN_6 PF17146.4 KXS12670.1 - 7e-27 93.8 0.5 1.4e-26 92.8 0.5 1.5 1 0 0 1 1 1 1 PIN domain of ribonuclease NOB1_Zn_bind PF08772.11 KXS12670.1 - 2.3e-15 56.5 0.1 6.4e-15 55.1 0.1 1.7 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like SDA1 PF05285.12 KXS12670.1 - 0.0039 16.7 11.9 0.006 16.0 11.9 1.3 1 0 0 1 1 1 1 SDA1 YL1 PF05764.13 KXS12670.1 - 0.07 13.2 13.8 0.12 12.5 13.8 1.3 1 0 0 1 1 1 0 YL1 nuclear protein CDC45 PF02724.14 KXS12670.1 - 1 7.6 12.4 1.4 7.1 12.4 1.1 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 KXS12670.1 - 1.4 8.1 24.8 2.4 7.4 24.8 1.2 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 KXS12670.1 - 3 5.9 20.1 4.3 5.4 20.1 1.1 1 0 0 1 1 1 0 Nop14-like family TEBP_beta PF07404.11 KXS12670.1 - 3.4 6.9 6.7 8.3 5.6 6.3 1.7 2 0 0 2 2 2 0 Telomere-binding protein beta subunit (TEBP beta) TFIIF_alpha PF05793.12 KXS12670.1 - 3.5 6.1 23.2 5.3 5.5 23.2 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Apt1 PF10351.9 KXS12670.1 - 7.1 5.4 8.1 10 4.9 8.1 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain BUD22 PF09073.10 KXS12671.1 - 0.82 8.9 7.2 0.35 10.1 1.0 2.1 2 0 0 2 2 2 0 BUD22 Amino_oxidase PF01593.24 KXS12673.1 - 0.058 12.7 0.0 0.058 12.7 0.0 1.1 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Ras PF00071.22 KXS12675.1 - 3.6e-43 147.0 0.1 4e-43 146.8 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXS12675.1 - 1.2e-11 44.9 0.0 1.8e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 KXS12675.1 - 1.6e-09 37.6 0.1 2.1e-09 37.2 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Arf PF00025.21 KXS12675.1 - 1.5e-08 34.3 0.1 1.8e-08 34.0 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KXS12675.1 - 0.00078 19.4 0.0 0.0012 18.7 0.0 1.3 1 1 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 KXS12675.1 - 0.0097 16.0 0.1 0.015 15.4 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 KXS12675.1 - 0.071 12.9 0.0 0.082 12.7 0.0 1.1 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein DUF1713 PF08213.11 KXS12676.1 - 0.00099 19.0 16.1 0.0016 18.3 16.1 1.3 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) THOC7 PF05615.13 KXS12676.1 - 0.023 15.0 0.1 0.035 14.4 0.1 1.2 1 0 0 1 1 1 0 Tho complex subunit 7 G-alpha PF00503.20 KXS12677.1 - 6.7e-121 403.8 5.2 7.7e-121 403.6 5.2 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KXS12677.1 - 7.7e-16 58.0 0.9 1e-10 41.3 0.1 2.6 2 0 0 2 2 2 2 ADP-ribosylation factor family zf-CHC2 PF01807.20 KXS12677.1 - 0.00025 20.8 0.1 0.0011 18.7 0.0 2.0 2 0 0 2 2 2 1 CHC2 zinc finger Gtr1_RagA PF04670.12 KXS12677.1 - 0.0039 16.6 5.0 0.13 11.6 0.4 2.7 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region AAA_15 PF13175.6 KXS12677.1 - 0.004 16.9 0.2 0.0098 15.6 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain Roc PF08477.13 KXS12677.1 - 0.005 17.0 1.4 1.7 8.9 0.0 2.8 3 0 0 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 KXS12677.1 - 0.0075 16.0 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain MCM PF00493.23 KXS12677.1 - 0.055 12.6 0.1 0.12 11.5 0.1 1.5 1 1 0 1 1 1 0 MCM P-loop domain FtsK_SpoIIIE PF01580.18 KXS12677.1 - 0.061 12.7 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family MMR_HSR1 PF01926.23 KXS12677.1 - 0.1 12.7 0.0 12 6.0 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KXS12677.1 - 0.18 11.3 1.0 4 6.9 0.1 2.7 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain EIF_2_alpha PF07541.12 KXS12678.1 - 3.6e-34 117.3 0.0 6.4e-34 116.5 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 KXS12678.1 - 3.3e-12 46.6 0.1 5.6e-12 45.8 0.1 1.4 1 0 0 1 1 1 1 S1 RNA binding domain MitMem_reg PF13012.6 KXS12679.1 - 1.5e-21 76.9 0.1 2.2e-21 76.3 0.1 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 KXS12679.1 - 1.2e-13 51.1 0.0 2.3e-13 50.2 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease FMO-like PF00743.19 KXS12680.1 - 1.7e-13 49.9 0.2 8.2e-13 47.6 0.2 2.0 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KXS12680.1 - 1.9e-11 43.7 0.0 7.3e-07 28.6 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KXS12680.1 - 4.6e-09 35.9 0.0 1.2e-07 31.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXS12680.1 - 6.1e-07 29.6 0.0 1.8e-06 28.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KXS12680.1 - 0.00043 19.6 0.0 0.0014 17.9 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXS12680.1 - 0.0098 15.9 0.0 0.17 11.9 0.0 2.7 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.24 KXS12680.1 - 0.041 13.5 1.0 4.9 6.6 1.5 3.2 3 1 1 4 4 4 0 FAD dependent oxidoreductase Thi4 PF01946.17 KXS12680.1 - 0.086 12.1 0.0 0.51 9.5 0.0 1.9 2 0 0 2 2 2 0 Thi4 family ODAPH PF15848.5 KXS12680.1 - 0.7 10.4 3.8 0.98 9.9 0.4 2.4 2 0 0 2 2 2 0 Odontogenesis associated phosphoprotein Trypsin PF00089.26 KXS12681.1 - 2.5e-21 76.5 2.3 3.4e-21 76.1 2.3 1.2 1 0 0 1 1 1 1 Trypsin PLA2_inh PF02988.15 KXS12681.1 - 0.49 11.1 4.1 0.15 12.8 0.6 1.9 2 0 0 2 2 2 0 Phospholipase A2 inhibitor AA_permease_2 PF13520.6 KXS12682.1 - 1.3e-28 100.0 19.0 1.6e-28 99.7 19.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXS12682.1 - 2.1e-13 49.7 18.7 2.5e-13 49.5 18.7 1.0 1 0 0 1 1 1 1 Amino acid permease F-box-like PF12937.7 KXS12685.1 - 0.0001 22.1 0.2 0.00021 21.1 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXS12685.1 - 0.0003 20.6 0.2 0.00077 19.3 0.2 1.7 1 0 0 1 1 1 1 F-box domain SIR2 PF02146.17 KXS12686.1 - 0.00027 20.9 0.2 0.00041 20.3 0.2 1.2 1 0 0 1 1 1 1 Sir2 family BIR PF00653.21 KXS12688.1 - 4.4e-35 120.2 1.0 1e-20 74.1 0.4 2.4 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain Ten1_2 PF15490.6 KXS12689.1 - 6.1e-17 61.4 0.0 6.8e-17 61.3 0.0 1.1 1 0 0 1 1 1 1 Telomere-capping, CST complex subunit Rep_fac-A_3 PF08661.11 KXS12689.1 - 0.027 14.8 0.0 0.035 14.5 0.0 1.1 1 0 0 1 1 1 0 Replication factor A protein 3 DUF3551 PF12071.8 KXS12690.1 - 0.011 15.8 0.3 1.3 9.1 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3551) TPR_12 PF13424.6 KXS12691.1 - 3.4e-155 504.7 59.4 3.9e-17 62.3 0.1 13.5 5 4 13 18 18 18 16 Tetratricopeptide repeat TPR_10 PF13374.6 KXS12691.1 - 2.1e-144 466.1 51.4 5.3e-13 48.4 0.1 19.3 21 0 0 21 21 20 16 Tetratricopeptide repeat TPR_7 PF13176.6 KXS12691.1 - 1.6e-55 181.2 27.3 0.00043 20.1 0.0 16.6 17 0 0 17 17 17 11 Tetratricopeptide repeat TPR_1 PF00515.28 KXS12691.1 - 2.2e-38 128.5 19.3 0.00078 19.2 0.0 15.6 17 0 0 17 17 16 10 Tetratricopeptide repeat TPR_8 PF13181.6 KXS12691.1 - 6.7e-35 116.4 23.2 0.1 12.8 0.0 15.9 16 0 0 16 16 15 8 Tetratricopeptide repeat TPR_2 PF07719.17 KXS12691.1 - 1.8e-30 102.5 30.3 0.078 13.1 0.0 15.7 16 0 0 16 16 15 8 Tetratricopeptide repeat TPR_14 PF13428.6 KXS12691.1 - 5.7e-25 85.9 57.4 0.14 13.0 0.0 18.6 12 5 8 20 20 19 6 Tetratricopeptide repeat TPR_19 PF14559.6 KXS12691.1 - 2.6e-22 79.1 58.1 0.0063 17.0 0.0 14.7 6 4 9 16 16 16 10 Tetratricopeptide repeat TPR_4 PF07721.14 KXS12691.1 - 2.6e-21 74.0 0.0 1.7 9.5 0.0 14.1 15 0 0 15 15 12 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KXS12691.1 - 9.3e-18 64.2 14.9 0.093 13.0 0.0 11.4 5 3 7 13 13 12 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 KXS12691.1 - 4.4e-16 58.4 46.9 0.29 11.9 0.1 16.8 17 0 0 17 17 17 4 Tetratricopeptide repeat TPR_17 PF13431.6 KXS12691.1 - 3e-14 52.3 26.0 0.34 11.4 0.1 14.2 16 0 0 16 16 13 3 Tetratricopeptide repeat Sel1 PF08238.12 KXS12691.1 - 1.3e-11 44.8 5.8 3.7e-06 27.4 0.9 6.2 7 0 0 7 7 4 2 Sel1 repeat PPR PF01535.20 KXS12691.1 - 1.2e-07 31.5 6.3 7.1 7.1 0.0 9.5 10 0 0 10 10 9 0 PPR repeat RPN7 PF10602.9 KXS12691.1 - 8.6e-07 28.8 16.1 1 9.0 0.0 8.9 3 1 3 9 9 9 2 26S proteasome subunit RPN7 TPR_16 PF13432.6 KXS12691.1 - 2.7e-06 27.9 57.5 0.014 16.0 0.3 13.6 11 4 4 15 15 13 3 Tetratricopeptide repeat ATG16 PF08614.11 KXS12691.1 - 2.7e-05 24.5 27.7 0.72 10.0 0.4 8.8 2 2 7 10 10 10 2 Autophagy protein 16 (ATG16) TPR_11 PF13414.6 KXS12691.1 - 0.00065 19.3 18.3 9.8 6.0 0.1 9.9 12 0 0 12 12 12 0 TPR repeat Pkinase_Tyr PF07714.17 KXS12691.1 - 0.011 15.1 0.0 0.022 14.0 0.0 1.6 1 0 0 1 1 1 0 Protein tyrosine kinase Glyco_hydro_115 PF15979.5 KXS12691.1 - 0.02 14.3 12.1 7.7 5.9 0.0 6.3 3 3 1 5 5 5 0 Glycosyl hydrolase family 115 Tcf25 PF04910.14 KXS12691.1 - 0.028 13.5 3.0 16 4.4 0.0 4.7 2 2 4 6 6 6 0 Transcriptional repressor TCF25 YqgF PF14639.6 KXS12691.1 - 0.032 14.0 0.6 0.22 11.3 0.1 2.6 2 0 0 2 2 2 0 Holliday-junction resolvase-like of SPT6 TPR_9 PF13371.6 KXS12691.1 - 0.04 14.1 26.8 1.5 9.0 0.3 8.8 6 3 3 10 10 8 0 Tetratricopeptide repeat UPF0052 PF01933.18 KXS12691.1 - 0.059 12.6 8.6 9.1 5.4 0.1 5.5 3 2 0 3 3 3 0 Uncharacterised protein family UPF0052 LAGLIDADG_2 PF03161.13 KXS12691.1 - 0.069 13.2 0.0 14 5.7 0.0 3.9 2 1 1 3 3 3 0 LAGLIDADG DNA endonuclease family Clathrin PF00637.20 KXS12691.1 - 0.16 11.9 11.0 0.19 11.6 0.2 6.0 4 2 2 7 7 7 0 Region in Clathrin and VPS DUF3896 PF13035.6 KXS12691.1 - 0.17 12.1 0.6 5.6 7.2 0.0 3.7 3 1 1 4 4 4 0 Protein of unknown function (DUF3896) DUF745 PF05335.13 KXS12691.1 - 0.57 9.9 30.7 0.34 10.6 0.4 7.5 3 3 4 8 8 8 0 Protein of unknown function (DUF745) Pkinase PF00069.25 KXS12692.1 - 1.4e-33 116.4 0.0 3.3e-33 115.2 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS12692.1 - 2.2e-32 112.4 0.0 1.2e-26 93.6 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KXS12692.1 - 0.00011 21.7 0.0 0.00075 18.9 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KXS12692.1 - 0.00016 21.1 0.0 0.00026 20.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXS12692.1 - 0.035 14.0 0.0 0.057 13.3 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 KXS12692.1 - 0.047 13.3 0.0 0.072 12.7 0.0 1.2 1 0 0 1 1 1 0 RIO1 family FTA2 PF13095.6 KXS12692.1 - 0.094 12.3 0.0 0.18 11.4 0.0 1.5 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 YoaP PF14268.6 KXS12694.1 - 0.0029 17.1 0.1 0.93 9.1 0.0 2.3 2 0 0 2 2 2 2 YoaP-like DUF2154 PF09922.9 KXS12694.1 - 0.016 15.1 0.0 0.018 14.9 0.0 1.2 1 0 0 1 1 1 0 Cell wall-active antibiotics response 4TMS YvqF Ank_2 PF12796.7 KXS12695.1 - 2.2e-20 73.0 0.3 6.1e-10 39.6 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXS12695.1 - 7.6e-20 71.0 0.3 1.1e-05 25.9 0.0 4.0 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXS12695.1 - 6.7e-14 50.7 2.3 0.25 12.0 0.1 5.1 5 0 0 5 5 5 5 Ankyrin repeat Ank PF00023.30 KXS12695.1 - 1.3e-13 50.7 10.2 0.00039 20.7 0.7 5.0 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 KXS12695.1 - 1.3e-10 41.3 2.2 0.019 15.3 0.0 5.0 2 1 3 5 5 5 4 Ankyrin repeats (many copies) DUF4246 PF14033.6 KXS12696.1 - 4.1e-64 217.3 0.0 4.4e-64 217.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) FLYWCH_N PF15423.6 KXS12698.1 - 0.073 13.2 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 FLYWCH-type zinc finger-containing protein DEAD PF00270.29 KXS12699.1 - 3.4e-32 111.6 0.1 5.6e-32 110.9 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXS12699.1 - 8.2e-28 97.0 0.0 1.8e-27 95.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXS12699.1 - 0.00052 20.1 0.0 0.0011 19.0 0.0 1.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 KXS12699.1 - 0.0029 17.4 0.2 0.0055 16.4 0.2 1.4 1 0 0 1 1 1 1 AAA domain Pertussis_S2S3 PF02918.15 KXS12700.1 - 0.066 13.1 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Pertussis toxin, subunit 2 and 3, C-terminal domain Herpes_LAMP2 PF06126.11 KXS12700.1 - 0.28 9.7 0.0 0.33 9.5 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus Latent membrane protein 2 Pkinase PF00069.25 KXS12701.1 - 1.2e-52 178.9 0.0 1.9e-52 178.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS12701.1 - 6.2e-21 74.8 0.2 4e-20 72.2 0.2 2.1 2 1 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 KXS12701.1 - 0.024 14.0 0.5 0.037 13.4 0.5 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXS12701.1 - 0.054 13.4 0.3 1.7 8.5 0.2 2.3 1 1 0 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.6 KXS12701.1 - 0.081 12.2 0.1 0.45 9.8 0.1 2.1 2 1 0 3 3 3 0 Kinase-like RIO1 PF01163.22 KXS12701.1 - 0.084 12.5 0.5 0.25 10.9 0.2 1.8 1 1 1 2 2 2 0 RIO1 family YIEGIA PF14045.6 KXS12701.1 - 0.23 10.3 0.0 0.36 9.6 0.0 1.2 1 0 0 1 1 1 0 YIEGIA protein Transglut_core2 PF13369.6 KXS12702.1 - 1.2e-34 119.1 0.0 1.9e-34 118.5 0.0 1.3 1 0 0 1 1 1 1 Transglutaminase-like superfamily F-box-like PF12937.7 KXS12702.1 - 3.7e-05 23.5 2.4 9e-05 22.3 2.4 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXS12702.1 - 0.16 11.9 2.6 0.13 12.2 0.5 2.0 2 0 0 2 2 2 0 F-box domain DUF2154 PF09922.9 KXS12703.1 - 3.4e-07 30.1 0.1 5.2e-07 29.5 0.1 1.2 1 0 0 1 1 1 1 Cell wall-active antibiotics response 4TMS YvqF SH3_9 PF14604.6 KXS12704.1 - 0.058 13.3 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Variant SH3 domain Ank_3 PF13606.6 KXS12705.1 - 7.8e-05 22.8 0.0 0.022 15.3 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.7 KXS12705.1 - 0.0024 18.4 0.0 0.11 13.1 0.0 2.9 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 KXS12705.1 - 0.0027 18.1 0.1 1.1 9.8 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 KXS12705.1 - 0.0036 17.9 0.0 0.02 15.5 0.0 2.2 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Cep57_MT_bd PF06657.13 KXS12705.1 - 0.0076 16.7 0.0 0.016 15.6 0.0 1.5 1 0 0 1 1 1 1 Centrosome microtubule-binding domain of Cep57 Ank_5 PF13857.6 KXS12705.1 - 0.026 14.9 0.0 0.16 12.3 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeats (many copies) F-box-like PF12937.7 KXS12706.1 - 0.00015 21.6 0.2 0.00036 20.4 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXS12706.1 - 0.014 15.2 0.1 0.047 13.6 0.1 1.9 1 0 0 1 1 1 0 F-box domain BTB_2 PF02214.22 KXS12708.1 - 6e-12 45.7 0.0 9.6e-12 45.1 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain F-box-like PF12937.7 KXS12710.1 - 0.0001 22.1 0.2 0.00021 21.1 0.2 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXS12710.1 - 0.00077 19.3 0.2 0.00077 19.3 0.2 1.8 2 0 0 2 2 2 1 F-box domain Myb_DNA-bind_3 PF12776.7 KXS12711.1 - 0.015 16.3 0.1 0.027 15.5 0.1 1.5 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain p450 PF00067.22 KXS12712.1 - 5.8e-78 262.7 0.0 7.5e-78 262.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 zf-C2H2 PF00096.26 KXS12715.1 - 0.075 13.5 1.4 0.075 13.5 1.4 2.4 2 1 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXS12715.1 - 8.1 7.6 8.8 1 10.4 2.4 2.8 2 1 0 2 2 2 0 C2H2-type zinc finger TPR_1 PF00515.28 KXS12717.1 - 1.9e-24 84.4 3.7 2.6e-08 33.4 0.1 5.7 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 KXS12717.1 - 1.4e-20 73.6 11.0 2.5e-07 31.2 0.0 3.5 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.17 KXS12717.1 - 5.7e-20 69.8 6.4 0.0003 20.7 0.0 5.7 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 KXS12717.1 - 1.3e-18 65.5 2.7 8.9e-06 25.5 0.1 5.5 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 KXS12717.1 - 9e-18 63.7 7.4 7.1e-07 28.8 0.1 5.1 3 1 1 4 4 4 3 TPR repeat TPR_14 PF13428.6 KXS12717.1 - 1.3e-17 63.0 5.0 0.00031 21.3 0.0 4.8 2 2 2 4 4 4 4 Tetratricopeptide repeat TPR_17 PF13431.6 KXS12717.1 - 4.1e-17 61.3 2.3 0.0031 17.8 0.0 5.5 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_19 PF14559.6 KXS12717.1 - 5.8e-16 58.8 4.9 5.9e-06 26.7 4.9 3.5 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 KXS12717.1 - 3.9e-11 43.1 5.4 4.1e-06 27.0 0.1 4.0 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_20 PF14561.6 KXS12717.1 - 5.7e-11 42.6 1.2 0.0026 18.0 0.1 5.0 2 2 3 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 KXS12717.1 - 1.6e-09 37.1 0.7 0.11 12.6 0.0 4.8 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_6 PF13174.6 KXS12717.1 - 2.2e-09 37.3 2.4 0.055 14.1 0.0 6.1 6 0 0 6 6 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KXS12717.1 - 1.6e-08 34.7 1.5 0.015 15.5 0.1 3.1 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 KXS12717.1 - 3.1e-07 30.4 1.3 0.052 13.7 0.0 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_3 PF07720.12 KXS12717.1 - 2.6e-05 24.1 0.1 0.041 13.9 0.1 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_15 PF13429.6 KXS12717.1 - 5.4e-05 22.6 0.1 0.11 11.7 0.1 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat MIT PF04212.18 KXS12717.1 - 5.5e-05 23.2 2.6 1.6 8.9 0.3 4.4 4 0 0 4 4 4 1 MIT (microtubule interacting and transport) domain TPR_10 PF13374.6 KXS12717.1 - 0.0018 18.1 4.9 0.64 10.0 0.2 4.8 4 1 1 5 5 5 1 Tetratricopeptide repeat DUF4810 PF16068.5 KXS12717.1 - 0.0031 18.0 0.0 0.082 13.5 0.0 2.7 2 1 1 3 3 3 1 Domain of unknown function (DUF4810) TPR_21 PF09976.9 KXS12717.1 - 0.01 15.6 2.2 1.5 8.5 0.8 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat-like domain SUV3_C PF12513.8 KXS12717.1 - 0.014 15.3 0.0 0.037 14.0 0.0 1.7 1 0 0 1 1 1 0 Mitochondrial degradasome RNA helicase subunit C terminal BTAD PF03704.17 KXS12717.1 - 0.093 13.2 1.6 4.5 7.7 0.0 2.5 2 0 0 2 2 2 0 Bacterial transcriptional activator domain MAS20 PF02064.15 KXS12717.1 - 0.13 12.3 0.1 19 5.4 0.0 3.3 2 1 2 4 4 3 0 MAS20 protein import receptor DUF1641 PF07849.11 KXS12717.1 - 0.17 11.8 0.2 0.17 11.8 0.2 1.7 2 0 0 2 2 1 0 Protein of unknown function (DUF1641) CMAS PF02353.20 KXS12718.1 - 2.4e-24 86.1 0.1 1.3e-22 80.4 0.1 2.2 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.6 KXS12718.1 - 1.8e-08 34.3 0.0 2.7e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXS12718.1 - 8.3e-08 32.2 0.1 2.3e-07 30.8 0.1 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KXS12718.1 - 4.5e-06 26.2 0.0 8.2e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 KXS12718.1 - 4.5e-06 27.3 0.0 9.4e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXS12718.1 - 9.5e-05 22.0 0.0 0.00015 21.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain GidB PF02527.15 KXS12718.1 - 0.00013 21.3 0.0 0.00021 20.7 0.0 1.2 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G TehB PF03848.14 KXS12718.1 - 0.0014 18.1 0.0 0.0021 17.5 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_12 PF08242.12 KXS12718.1 - 0.0016 19.1 0.0 0.043 14.6 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain tRNA_U5-meth_tr PF05958.11 KXS12718.1 - 0.0041 16.1 0.0 0.0057 15.7 0.0 1.1 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Plasmod_MYXSPDY PF07981.11 KXS12718.1 - 0.006 16.5 2.5 0.016 15.2 2.5 1.7 1 0 0 1 1 1 1 Plasmodium repeat_MYXSPDY Methyltransf_11 PF08241.12 KXS12718.1 - 0.0065 17.1 0.0 0.02 15.5 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase domain GcpE PF04551.14 KXS12718.1 - 0.038 13.1 0.0 0.054 12.6 0.0 1.1 1 0 0 1 1 1 0 GcpE protein Methyltr_RsmB-F PF01189.17 KXS12718.1 - 0.056 13.1 0.0 0.093 12.4 0.0 1.2 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F Sulfotransfer_4 PF17784.1 KXS12718.1 - 0.062 13.1 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Sulfotransferase domain PCMT PF01135.19 KXS12718.1 - 0.15 11.8 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DEAD PF00270.29 KXS12719.1 - 4e-46 157.0 0.0 6.6e-46 156.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXS12719.1 - 2.7e-26 92.1 0.0 7.3e-26 90.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXS12719.1 - 0.0068 16.4 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Rab5ip PF07019.12 KXS12720.1 - 7e-21 74.6 7.9 8.4e-21 74.4 7.9 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) Cu-oxidase_2 PF07731.14 KXS12722.1 - 1.1e-42 145.0 8.6 5.2e-41 139.6 0.1 3.2 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 KXS12722.1 - 1.9e-38 132.1 4.1 6.2e-33 114.2 0.7 3.0 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KXS12722.1 - 1.5e-35 121.8 8.3 9.6e-32 109.5 1.3 3.9 4 1 0 4 4 4 2 Multicopper oxidase Cupredoxin_1 PF13473.6 KXS12722.1 - 0.00061 19.9 0.0 0.1 12.8 0.0 3.7 3 2 0 3 3 3 1 Cupredoxin-like domain FTR1 PF03239.14 KXS12723.1 - 1.3e-69 234.7 9.0 1.7e-69 234.3 9.0 1.1 1 0 0 1 1 1 1 Iron permease FTR1 family CoA_binding_3 PF13727.6 KXS12723.1 - 0.031 14.3 0.1 0.031 14.3 0.1 2.5 3 1 0 3 3 3 0 CoA-binding domain YebO PF13974.6 KXS12723.1 - 0.19 11.8 0.2 8.1 6.6 0.4 2.5 2 0 0 2 2 2 0 YebO-like protein DUF3180 PF11377.8 KXS12723.1 - 2.8 8.1 14.4 1.4 9.0 2.3 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF3180) DUF3341 PF11821.8 KXS12723.1 - 5.3 6.7 8.2 1.3 8.6 0.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3341) DUF4418 PF14387.6 KXS12723.1 - 6.8 6.9 9.7 5.8 7.1 1.0 3.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4418) Aldo_ket_red PF00248.21 KXS12724.1 - 1.1e-32 113.4 0.0 1.4e-32 113.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF3930 PF13067.6 KXS12725.1 - 0.17 12.2 0.4 0.36 11.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3930) Aldo_ket_red PF00248.21 KXS12726.1 - 5.8e-52 176.7 0.0 7e-52 176.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family MBOAT PF03062.19 KXS12727.1 - 2.7e-29 102.6 10.5 7.1e-29 101.2 10.1 1.9 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family DUF373 PF04123.13 KXS12727.1 - 1.9 7.8 5.9 0.87 9.0 0.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF373) MFS_1 PF07690.16 KXS12728.1 - 9.5e-39 133.3 17.1 2.9e-31 108.7 7.2 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXS12728.1 - 3e-06 26.4 2.5 3e-06 26.4 2.5 3.0 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KXS12728.1 - 0.00045 18.8 0.1 0.00062 18.3 0.1 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 KXS12728.1 - 0.0037 15.7 9.1 0.023 13.1 2.6 3.0 2 1 0 2 2 2 2 Transmembrane secretion effector CPP1-like PF11833.8 KXS12728.1 - 0.0084 15.8 2.4 0.012 15.3 1.2 1.8 2 0 0 2 2 2 1 Protein CHAPERONE-LIKE PROTEIN OF POR1-like NrsF PF06532.11 KXS12728.1 - 0.026 14.2 0.4 0.026 14.2 0.4 2.1 3 0 0 3 3 3 0 Negative regulator of sigma F MFS_1_like PF12832.7 KXS12728.1 - 0.093 11.6 5.7 0.42 9.4 0.2 2.5 1 1 1 2 2 2 0 MFS_1 like family DUF3866 PF12982.7 KXS12728.1 - 0.17 10.9 0.0 0.27 10.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3866) Peptidase_A22B PF04258.13 KXS12732.1 - 9.6e-52 176.3 6.9 7.5e-35 120.8 3.0 2.3 2 0 0 2 2 2 2 Signal peptide peptidase FA_desaturase PF00487.24 KXS12732.1 - 3.4 7.4 16.6 0.052 13.4 0.7 3.1 2 1 1 3 3 3 0 Fatty acid desaturase PAN_4 PF14295.6 KXS12734.1 - 6.5 6.7 9.3 21 5.1 0.8 3.6 3 0 0 3 3 3 0 PAN domain SH3_9 PF14604.6 KXS12735.1 - 5.9e-05 22.8 0.0 0.00012 21.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXS12735.1 - 0.00018 21.1 0.0 0.00034 20.2 0.0 1.5 1 0 0 1 1 1 1 SH3 domain Stig1 PF04885.13 KXS12735.1 - 0.011 16.2 7.1 0.011 16.2 7.1 2.0 2 0 0 2 2 2 0 Stigma-specific protein, Stig1 SH3_9 PF14604.6 KXS12737.1 - 1.1e-06 28.4 0.1 2e-06 27.6 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXS12737.1 - 0.0035 16.9 0.0 0.0068 16.0 0.0 1.5 1 0 0 1 1 1 1 SH3 domain DUF3602 PF12223.8 KXS12737.1 - 0.013 16.1 2.5 0.68 10.6 2.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3602) Phage_HK97_TLTM PF06120.11 KXS12737.1 - 0.24 10.6 0.3 0.34 10.1 0.3 1.2 1 0 0 1 1 1 0 Tail length tape measure protein SH3_9 PF14604.6 KXS12738.1 - 1.2e-06 28.3 0.0 2e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXS12738.1 - 0.023 14.3 0.0 0.042 13.5 0.0 1.4 1 0 0 1 1 1 0 SH3 domain Stig1 PF04885.13 KXS12738.1 - 0.034 14.6 10.8 0.095 13.2 10.8 1.7 1 0 0 1 1 1 0 Stigma-specific protein, Stig1 DUF2358 PF10184.9 KXS12739.1 - 4.4e-14 52.7 0.0 5.4e-08 33.1 0.0 2.2 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2358) MMU163 PF17119.5 KXS12739.1 - 4.3e-06 26.1 0.0 0.015 14.5 0.0 2.4 1 1 0 2 2 2 2 Mitochondrial protein up-regulated during meiosis SnoaL_2 PF12680.7 KXS12739.1 - 0.013 16.1 0.1 0.29 11.8 0.1 2.3 1 1 0 1 1 1 0 SnoaL-like domain FAD_binding_2 PF00890.24 KXS12740.1 - 1.5e-125 419.5 3.5 2.1e-125 419.1 3.5 1.2 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 KXS12740.1 - 4.5e-44 149.5 3.7 6.7e-44 149.0 3.7 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Thi4 PF01946.17 KXS12740.1 - 0.0016 17.7 0.6 1.5 8.0 0.1 2.5 2 0 0 2 2 2 2 Thi4 family FAD_binding_3 PF01494.19 KXS12740.1 - 0.003 16.9 0.2 0.0052 16.1 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 KXS12740.1 - 0.0035 16.5 1.7 0.24 10.4 1.9 2.4 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 KXS12740.1 - 0.0062 15.8 0.5 0.025 13.8 0.1 2.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXS12740.1 - 0.33 9.6 1.3 4.8 5.8 0.5 2.9 4 0 0 4 4 4 0 HI0933-like protein MFS_1 PF07690.16 KXS12741.1 - 2.8e-51 174.5 47.4 1.1e-39 136.4 25.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXS12741.1 - 2.8e-11 42.9 15.7 1e-07 31.2 2.0 2.7 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.7 KXS12741.1 - 3.2e-06 26.3 4.0 0.0011 17.9 0.4 2.3 2 0 0 2 2 2 2 MFS_1 like family MFS_3 PF05977.13 KXS12741.1 - 2.7e-05 22.8 26.3 0.0052 15.2 13.5 2.1 2 0 0 2 2 2 2 Transmembrane secretion effector OATP PF03137.20 KXS12741.1 - 0.0047 15.3 8.7 0.27 9.5 0.1 3.1 2 1 1 3 3 3 3 Organic Anion Transporter Polypeptide (OATP) family LacY_symp PF01306.19 KXS12741.1 - 0.076 11.8 4.6 0.018 13.9 0.8 1.8 2 1 0 2 2 2 0 LacY proton/sugar symporter NAD_Gly3P_dh_C PF07479.14 KXS12742.1 - 4.2e-43 147.0 0.1 6.1e-43 146.5 0.1 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.23 KXS12742.1 - 1e-35 123.1 0.0 1.4e-35 122.6 0.0 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.17 KXS12742.1 - 2.2e-06 28.2 0.0 1.2e-05 25.8 0.0 2.2 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 KXS12742.1 - 1.8e-05 24.5 0.0 2.8e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_2 PF03446.15 KXS12742.1 - 0.00016 21.9 0.0 0.00046 20.4 0.0 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase UDPG_MGDP_dh_N PF03721.14 KXS12742.1 - 0.0015 18.1 0.0 0.0024 17.5 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Shikimate_DH PF01488.20 KXS12742.1 - 0.021 14.9 0.0 0.046 13.8 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 KXS12742.1 - 0.022 14.1 0.0 0.099 12.0 0.0 2.0 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 KXS12742.1 - 0.042 14.1 0.0 0.19 12.0 0.0 2.0 2 0 0 2 2 2 0 TrkA-N domain 3HCDH_N PF02737.18 KXS12742.1 - 0.15 11.9 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain IlvN PF07991.12 KXS12742.1 - 0.15 11.6 0.0 0.62 9.6 0.0 1.9 1 1 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Sacchrp_dh_NADP PF03435.18 KXS12742.1 - 0.16 12.2 0.0 1 9.6 0.0 2.1 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain zf-C2H2 PF00096.26 KXS12744.1 - 5.7e-08 32.8 6.1 0.0006 20.1 0.7 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXS12744.1 - 2.9e-06 27.6 5.2 0.043 14.6 0.7 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KXS12744.1 - 4.2e-06 27.0 1.9 4.2e-06 27.0 1.9 2.5 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_11 PF16622.5 KXS12744.1 - 0.044 13.5 0.8 0.3 10.9 1.0 2.1 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 KXS12744.1 - 0.58 10.2 3.7 16 5.6 0.1 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger Auts2 PF15336.6 KXS12746.1 - 9.2 6.3 10.9 4.4 7.4 0.7 2.2 2 0 0 2 2 2 0 Autism susceptibility gene 2 protein Exo_endo_phos PF03372.23 KXS12747.1 - 4.6e-20 72.1 0.3 9e-20 71.2 0.3 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family MFS_1 PF07690.16 KXS12748.1 - 6.5e-23 81.2 32.3 7.8e-23 80.9 32.3 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Cupin_2 PF07883.11 KXS12749.1 - 5.7e-12 45.2 0.1 1.2e-11 44.1 0.1 1.6 1 1 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 KXS12749.1 - 2.8e-05 23.8 0.0 3.3e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Cupin Cupin_7 PF12973.7 KXS12749.1 - 4.4e-05 23.3 0.1 0.00011 22.1 0.1 1.6 1 1 1 2 2 2 1 ChrR Cupin-like domain GPI PF06560.11 KXS12749.1 - 0.0019 17.5 0.0 0.0027 17.0 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate isomerase (GPI) Cupin_3 PF05899.12 KXS12749.1 - 0.0028 17.3 0.0 0.0045 16.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF861) AraC_binding PF02311.19 KXS12749.1 - 0.0048 16.8 0.0 0.0071 16.2 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_6 PF12852.7 KXS12749.1 - 0.019 14.7 0.0 0.022 14.5 0.0 1.1 1 0 0 1 1 1 0 Cupin ARD PF03079.14 KXS12749.1 - 0.1 12.8 0.0 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 ARD/ARD' family TMC PF07810.13 KXS12750.1 - 8.9e-17 61.7 0.5 1.7e-16 60.8 0.2 1.7 2 0 0 2 2 2 1 TMC domain DUF4381 PF14316.6 KXS12750.1 - 0.079 13.2 0.6 0.15 12.3 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF2207 PF09972.9 KXS12750.1 - 9.1 4.9 7.7 1.6 7.4 0.5 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) Sel1 PF08238.12 KXS12751.1 - 2.2e-18 66.3 33.8 0.00074 20.1 0.2 9.6 9 0 0 9 9 9 6 Sel1 repeat zf-H2C2_2 PF13465.6 KXS12752.1 - 2.9e-08 33.8 1.5 9.5e-08 32.1 1.5 2.0 1 0 0 1 1 1 1 Zinc-finger double domain zf-C2H2 PF00096.26 KXS12752.1 - 8.3e-06 26.0 12.1 4.6e-05 23.6 1.7 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXS12752.1 - 1.7e-05 25.2 7.3 0.022 15.6 1.4 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf_C2H2_6 PF18450.1 KXS12752.1 - 0.38 10.5 3.6 0.51 10.1 1.4 2.1 2 0 0 2 2 2 0 Zinc Finger domain zf-C2H2_11 PF16622.5 KXS12752.1 - 3.3 7.6 4.1 6.5 6.6 0.2 2.4 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-H2C2_5 PF13909.6 KXS12752.1 - 5 7.0 8.4 0.4 10.5 0.5 2.9 2 1 0 2 2 2 0 C2H2-type zinc-finger domain SGL PF08450.12 KXS12753.1 - 1.3e-19 70.8 0.0 4.3e-12 46.2 0.0 2.1 2 0 0 2 2 2 2 SMP-30/Gluconolactonase/LRE-like region Pirin PF02678.16 KXS12754.1 - 4.2e-31 107.1 0.0 8.3e-31 106.2 0.0 1.5 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 KXS12754.1 - 2.8e-26 91.9 0.0 3.4e-25 88.4 0.0 2.1 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.11 KXS12754.1 - 0.2 11.4 2.7 3.3 7.5 0.2 3.1 3 0 0 3 3 3 0 Cupin domain ADH_zinc_N PF00107.26 KXS12756.1 - 3.4e-12 46.5 0.1 4.7e-12 46.0 0.1 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KXS12756.1 - 5.3e-05 22.6 0.7 6.3e-05 22.4 0.7 1.1 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 KXS12756.1 - 0.0047 16.3 0.2 0.0061 15.9 0.2 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 KXS12756.1 - 0.093 12.6 0.1 0.11 12.4 0.1 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F-box-like PF12937.7 KXS12758.1 - 4.9e-08 32.7 0.2 5.3e-08 32.6 0.2 1.1 1 0 0 1 1 1 1 F-box-like F-box_5 PF18511.1 KXS12758.1 - 0.0066 16.0 0.6 0.011 15.3 0.6 1.3 1 0 0 1 1 1 1 F-box F-box PF00646.33 KXS12758.1 - 0.031 14.2 2.6 0.22 11.4 2.6 2.0 1 1 0 1 1 1 0 F-box domain Phage_CRI PF05144.14 KXS12758.1 - 0.26 10.6 0.0 0.26 10.6 0.0 1.1 1 0 0 1 1 1 0 Phage replication protein CRI Pex24p PF06398.11 KXS12759.1 - 6.2e-11 41.9 3.5 1.2e-10 40.9 3.5 1.5 1 1 0 1 1 1 1 Integral peroxisomal membrane peroxin zf-MYND PF01753.18 KXS12760.1 - 3.6e-12 46.2 13.9 6.1e-12 45.4 13.9 1.4 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KXS12760.1 - 0.029 14.7 8.8 0.029 14.7 8.8 1.8 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding zf-BED PF02892.15 KXS12761.1 - 4.6 7.4 6.6 18 5.4 6.2 2.2 2 1 0 2 2 2 0 BED zinc finger Med21 PF11221.8 KXS12765.1 - 1.2e-21 77.5 0.6 2e-21 76.7 0.6 1.3 1 0 0 1 1 1 1 Subunit 21 of Mediator complex Glyoxalase PF00903.25 KXS12765.1 - 1.2e-14 54.6 0.0 5.6e-14 52.4 0.0 1.9 2 0 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KXS12765.1 - 6.8e-09 36.0 0.0 1.5e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Med9 PF07544.13 KXS12765.1 - 0.001 19.1 0.4 0.001 19.1 0.4 2.0 2 0 0 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 CppA_N PF14506.6 KXS12765.1 - 0.0017 18.4 0.5 0.011 15.8 0.0 2.2 2 1 0 2 2 2 1 CppA N-terminal Glyoxalase_2 PF12681.7 KXS12765.1 - 0.019 14.9 0.1 0.079 12.9 0.0 2.0 2 1 1 3 3 3 0 Glyoxalase-like domain RMI1_N PF08585.12 KXS12765.1 - 0.083 12.6 0.1 0.12 12.1 0.1 1.2 1 0 0 1 1 1 0 RecQ mediated genome instability protein SH3_9 PF14604.6 KXS12767.1 - 1.3e-06 28.2 0.0 2.5e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXS12767.1 - 0.0027 17.3 0.0 0.0048 16.5 0.0 1.4 1 0 0 1 1 1 1 SH3 domain Stig1 PF04885.13 KXS12767.1 - 9 6.8 16.8 20 5.6 16.8 1.5 1 0 0 1 1 1 0 Stigma-specific protein, Stig1 2-Hacid_dh_C PF02826.19 KXS12769.1 - 7.4e-36 123.2 0.3 4.6e-33 114.1 0.3 2.2 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KXS12769.1 - 2.8e-15 56.1 0.0 4.6e-13 49.0 0.0 2.1 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain adh_short PF00106.25 KXS12769.1 - 0.0023 17.4 0.2 0.0046 16.4 0.2 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXS12769.1 - 0.14 12.1 0.0 0.33 10.8 0.0 1.6 1 0 0 1 1 1 0 KR domain adh_short PF00106.25 KXS12770.1 - 1.7e-41 141.9 0.1 2.1e-41 141.5 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXS12770.1 - 6.1e-27 94.7 0.3 7.7e-27 94.3 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXS12770.1 - 4.1e-10 39.8 0.1 6.4e-10 39.2 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXS12770.1 - 0.039 13.4 0.1 2.7 7.4 0.1 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Methyltransf_16 PF10294.9 KXS12771.1 - 3.3e-14 53.0 0.0 1.1e-08 35.0 0.0 2.1 2 0 0 2 2 2 2 Lysine methyltransferase MTS PF05175.14 KXS12771.1 - 5.5e-05 22.8 0.0 0.0001 21.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 KXS12771.1 - 0.0007 20.3 0.1 0.0018 19.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXS12771.1 - 0.013 15.3 0.0 0.02 14.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 KXS12771.1 - 0.023 14.1 0.0 0.035 13.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 KXS12771.1 - 0.067 13.9 0.0 0.14 12.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 KXS12771.1 - 0.11 12.3 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ecm29 PF13001.7 KXS12772.1 - 1.9e-126 422.7 0.0 2.1e-124 416.0 0.0 3.5 5 0 0 5 5 5 1 Proteasome stabiliser HEAT_EZ PF13513.6 KXS12772.1 - 2.1e-06 28.1 3.3 0.0069 16.9 0.0 7.4 6 1 1 7 7 7 1 HEAT-like repeat HEAT_2 PF13646.6 KXS12772.1 - 5.9e-06 26.6 8.3 0.45 10.9 0.0 8.5 9 0 0 9 9 9 1 HEAT repeats Dopey_N PF04118.14 KXS12772.1 - 0.00034 19.8 0.2 2 7.5 0.0 4.0 4 0 0 4 4 4 2 Dopey, N-terminal HEAT PF02985.22 KXS12772.1 - 0.00036 20.6 11.3 0.39 11.1 0.1 7.9 8 0 0 8 8 8 1 HEAT repeat MMS19_N PF14500.6 KXS12772.1 - 0.00037 20.2 4.6 0.42 10.2 0.2 5.2 4 2 2 6 6 6 2 Dos2-interacting transcription regulator of RNA-Pol-II Vac14_Fab1_bd PF12755.7 KXS12772.1 - 0.00047 20.7 0.0 0.2 12.3 0.0 4.5 3 1 1 4 4 4 1 Vacuolar 14 Fab1-binding region Arm PF00514.23 KXS12772.1 - 0.0026 17.7 2.5 0.47 10.6 0.0 5.0 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat RhoGAP PF00620.27 KXS12772.1 - 0.021 14.6 0.1 0.16 11.8 0.1 2.5 2 0 0 2 2 2 0 RhoGAP domain IBN_N PF03810.19 KXS12772.1 - 0.84 9.6 3.0 30 4.6 0.0 4.1 4 0 0 4 4 4 0 Importin-beta N-terminal domain Adaptin_N PF01602.20 KXS12772.1 - 1.3 7.5 5.0 15 4.0 0.1 3.8 4 1 0 4 4 4 0 Adaptin N terminal region Aminotran_5 PF00266.19 KXS12773.1 - 3.1e-40 138.3 0.0 3.5e-40 138.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V NAS PF03059.16 KXS12774.1 - 5.8e-36 124.3 0.0 1.7e-35 122.7 0.0 1.6 1 1 0 1 1 1 1 Nicotianamine synthase protein Methyltransf_25 PF13649.6 KXS12774.1 - 1.3e-05 25.8 0.0 2.6e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXS12774.1 - 1.5e-05 24.8 0.0 2.3e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXS12774.1 - 8.6e-05 23.2 0.0 0.00018 22.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXS12774.1 - 0.0048 17.5 0.1 0.0087 16.7 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.21 KXS12775.1 - 1.9e-23 83.2 0.4 5.7e-11 42.3 0.0 3.0 1 1 1 2 2 2 2 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXS12775.1 - 2e-11 43.9 0.2 1.6e-05 24.5 0.1 3.3 3 1 0 3 3 3 3 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KXS12775.1 - 5.1e-09 36.3 0.0 1.4e-08 34.9 0.0 1.7 2 0 0 2 2 2 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 KXS12775.1 - 6.4e-07 28.7 0.0 0.00021 20.5 0.0 2.3 2 0 0 2 2 2 2 RmlD substrate binding domain 3Beta_HSD PF01073.19 KXS12775.1 - 9.3e-07 28.1 0.0 0.011 14.8 0.0 2.3 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KXS12775.1 - 3.9e-06 26.2 0.0 0.5 9.4 0.0 3.2 3 0 0 3 3 3 2 Polysaccharide biosynthesis protein adh_short PF00106.25 KXS12775.1 - 0.00021 20.8 0.0 0.0004 19.9 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.13 KXS12775.1 - 0.00026 20.6 0.1 0.0033 17.0 0.0 2.1 2 0 0 2 2 2 1 NmrA-like family NAD_binding_4 PF07993.12 KXS12775.1 - 0.006 15.8 0.1 0.043 13.0 0.0 2.3 2 1 0 3 3 3 1 Male sterility protein DapB_N PF01113.20 KXS12775.1 - 0.0065 16.6 0.0 0.18 11.9 0.0 2.8 3 0 0 3 3 3 1 Dihydrodipicolinate reductase, N-terminus KR PF08659.10 KXS12775.1 - 0.0092 15.9 0.0 0.022 14.7 0.0 1.6 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KXS12775.1 - 0.029 14.2 0.1 0.1 12.5 0.0 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 KXS12775.1 - 0.059 12.7 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 KXS12775.1 - 0.19 12.3 0.3 0.8 10.3 0.0 2.1 3 0 0 3 3 2 0 NADP oxidoreductase coenzyme F420-dependent RabGAP-TBC PF00566.18 KXS12776.1 - 3.6e-10 39.9 0.1 9.2e-10 38.5 0.1 1.5 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Nha1_C PF08619.10 KXS12776.1 - 0.018 14.2 4.8 0.03 13.6 4.8 1.2 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus FAM176 PF14851.6 KXS12776.1 - 0.44 10.2 5.3 0.22 11.2 2.0 2.1 2 0 0 2 2 2 0 FAM176 family NOA36 PF06524.12 KXS12776.1 - 2 7.6 5.1 3.4 6.9 5.1 1.3 1 0 0 1 1 1 0 NOA36 protein C2 PF00168.30 KXS12777.1 - 2.5e-59 197.9 0.0 3e-18 66.0 0.0 4.3 4 0 0 4 4 4 4 C2 domain MMM1 PF10296.9 KXS12777.1 - 8.1e-05 21.8 0.0 0.00013 21.2 0.0 1.2 1 0 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 DSBA PF01323.20 KXS12778.1 - 9.1e-23 81.0 0.0 4.4e-10 39.6 0.0 2.2 2 0 0 2 2 2 2 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 KXS12778.1 - 0.0054 16.9 0.0 0.94 9.6 0.0 2.2 2 0 0 2 2 2 2 Thioredoxin HSP70 PF00012.20 KXS12779.1 - 1.9e-261 868.6 6.0 2.1e-261 868.4 6.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KXS12779.1 - 4.1e-16 58.7 0.1 8.4e-15 54.4 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein Hydantoinase_A PF01968.18 KXS12779.1 - 0.013 14.8 0.1 0.027 13.7 0.1 1.6 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase FGGY_C PF02782.16 KXS12779.1 - 0.036 13.8 0.0 0.13 12.0 0.0 1.9 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.20 KXS12779.1 - 0.049 13.1 0.1 4.4 6.7 0.0 2.5 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family GRP PF07172.11 KXS12779.1 - 0.1 13.3 8.9 0.25 12.1 8.9 1.6 1 0 0 1 1 1 0 Glycine rich protein family SH3_9 PF14604.6 KXS12781.1 - 5.4e-05 23.0 0.0 0.0001 22.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain zf-MYND PF01753.18 KXS12782.1 - 3.7e-06 26.9 6.9 5.6e-06 26.4 6.9 1.3 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.16 KXS12782.1 - 0.077 12.9 6.8 0.15 11.9 6.8 1.5 1 0 0 1 1 1 0 HIT zinc finger AA_permease_2 PF13520.6 KXS12783.1 - 3.1e-49 168.0 40.1 4.1e-49 167.6 40.1 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXS12783.1 - 1.7e-19 69.8 37.2 1.7e-19 69.8 37.2 1.7 1 1 0 1 1 1 1 Amino acid permease FAD_binding_8 PF08022.12 KXS12785.1 - 5.3e-13 49.0 0.0 1.3e-12 47.7 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 KXS12785.1 - 1.8e-12 47.7 0.1 1.4e-11 44.7 0.1 2.1 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 KXS12785.1 - 1.8e-08 34.5 12.3 0.00012 22.1 0.3 2.6 2 0 0 2 2 2 2 Ferric reductase like transmembrane component NAD_binding_1 PF00175.21 KXS12785.1 - 0.0016 19.1 2.6 0.05 14.3 2.6 2.3 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KXS12785.1 - 0.023 15.0 0.0 0.12 12.8 0.0 2.2 2 0 0 2 2 2 0 Oxidoreductase FAD-binding domain Reeler PF02014.16 KXS12786.1 - 8.8e-09 36.2 0.0 1.6e-08 35.3 0.0 1.4 1 0 0 1 1 1 1 Reeler domain Reeler PF02014.16 KXS12787.1 - 2.4e-10 41.2 0.2 4e-10 40.6 0.2 1.3 1 0 0 1 1 1 1 Reeler domain Reeler PF02014.16 KXS12788.1 - 0.0057 17.4 0.0 0.0079 16.9 0.0 1.2 1 0 0 1 1 1 1 Reeler domain Peptidase_M56 PF05569.11 KXS12788.1 - 0.12 11.5 0.4 0.17 11.0 0.4 1.1 1 0 0 1 1 1 0 BlaR1 peptidase M56 F-box-like PF12937.7 KXS12790.1 - 0.0068 16.3 0.1 0.014 15.3 0.1 1.5 1 0 0 1 1 1 1 F-box-like Ribosomal_S27e PF01667.17 KXS12791.1 - 0.0032 17.2 1.4 0.19 11.5 0.0 2.3 1 1 1 2 2 2 2 Ribosomal protein S27 CCDC144C PF14915.6 KXS12792.1 - 0.0017 17.6 0.8 0.0021 17.2 0.8 1.1 1 0 0 1 1 1 1 CCDC144C protein coiled-coil region DUF3375 PF11855.8 KXS12792.1 - 0.016 14.1 0.2 0.019 13.9 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3375) bZIP_2 PF07716.15 KXS12792.1 - 0.022 14.8 0.3 0.047 13.8 0.3 1.4 1 0 0 1 1 1 0 Basic region leucine zipper GIT_CC PF16559.5 KXS12792.1 - 0.35 10.8 3.7 5.9 6.8 0.4 2.2 1 1 1 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor AAA_16 PF13191.6 KXS12793.1 - 0.001 19.5 0.0 0.0019 18.6 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain TsaE PF02367.17 KXS12793.1 - 0.027 14.5 0.0 0.049 13.6 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 KXS12793.1 - 0.041 14.1 0.0 0.087 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KXS12793.1 - 0.042 14.4 0.0 0.081 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KXS12793.1 - 0.069 13.6 0.0 0.16 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KXS12793.1 - 0.13 11.6 0.0 0.24 10.6 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin DUF1944 PF09175.10 KXS12793.1 - 0.15 11.9 0.0 0.24 11.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1944) PRK PF00485.18 KXS12793.1 - 0.18 11.5 0.0 0.76 9.5 0.0 2.0 1 1 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA PF00004.29 KXS12793.1 - 0.19 12.2 0.0 0.43 11.0 0.0 1.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF2362 PF10154.9 KXS12794.1 - 8.1e-06 25.1 0.0 1e-05 24.7 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2362) PB1 PF00564.24 KXS12794.1 - 0.029 14.3 0.0 0.094 12.7 0.0 1.8 2 0 0 2 2 2 0 PB1 domain DUF2362 PF10154.9 KXS12795.1 - 1.1e-60 206.1 0.0 2.1e-58 198.5 0.0 2.2 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2362) Fungal_trans PF04082.18 KXS12796.1 - 1.3e-18 67.0 1.2 1.8e-18 66.6 1.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXS12796.1 - 2.5e-09 37.1 12.5 5e-09 36.1 12.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 4HBT_3 PF13622.6 KXS12797.1 - 3.8e-19 69.9 0.0 7.4e-19 69.0 0.0 1.4 1 0 0 1 1 1 1 Thioesterase-like superfamily PDEase_I PF00233.19 KXS12798.1 - 1.7e-13 50.9 0.1 1.9e-08 34.4 0.0 2.4 2 0 0 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase TPMT PF05724.11 KXS12799.1 - 0.033 13.9 0.0 0.059 13.0 0.0 1.3 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) TRAPPC9-Trs120 PF08626.11 KXS12799.1 - 0.15 9.4 0.0 0.18 9.1 0.0 1.0 1 0 0 1 1 1 0 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit His_Phos_2 PF00328.22 KXS12800.1 - 6.3e-24 85.0 0.0 3.6e-23 82.6 0.0 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) His_Phos_1 PF00300.22 KXS12800.1 - 0.0079 15.9 0.0 0.031 14.0 0.0 2.0 2 1 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) RNA_pol_A_bac PF01000.26 KXS12801.1 - 1.6e-24 86.4 0.0 3.2e-24 85.5 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 KXS12801.1 - 8e-22 76.5 0.0 2.4e-21 74.9 0.0 1.7 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Ran_BP1 PF00638.18 KXS12802.1 - 1.5e-11 44.6 0.1 2.5e-11 43.9 0.1 1.3 1 0 0 1 1 1 1 RanBP1 domain NUP50 PF08911.11 KXS12802.1 - 4.4e-07 30.5 0.3 4.4e-07 30.5 0.3 4.0 3 1 0 3 3 3 1 NUP50 (Nucleoporin 50 kDa) MIIP PF15734.5 KXS12804.1 - 1.2e-08 34.9 0.1 1.4e-08 34.6 0.1 1.1 1 0 0 1 1 1 1 Migration and invasion-inhibitory Cupin_2 PF07883.11 KXS12805.1 - 1.2e-13 50.6 1.5 1.5e-06 27.8 0.1 3.1 3 0 0 3 3 3 2 Cupin domain Cupin_3 PF05899.12 KXS12805.1 - 4.8e-08 32.6 0.1 0.00086 19.0 0.0 3.2 3 0 0 3 3 3 2 Protein of unknown function (DUF861) Cupin_6 PF12852.7 KXS12805.1 - 9.9e-06 25.4 0.9 0.064 13.0 0.1 2.8 3 0 0 3 3 3 2 Cupin AraC_binding PF02311.19 KXS12805.1 - 0.00016 21.6 0.8 0.011 15.6 0.4 2.3 2 0 0 2 2 2 1 AraC-like ligand binding domain HutD PF05962.11 KXS12805.1 - 0.013 15.4 0.0 5.2 7.0 0.0 2.4 2 0 0 2 2 2 0 HutD Ectoine_synth PF06339.12 KXS12805.1 - 0.057 13.6 0.1 0.15 12.3 0.1 1.6 2 0 0 2 2 2 0 Ectoine synthase RNase_II_C_S1 PF18614.1 KXS12805.1 - 0.15 12.1 0.6 20 5.2 0.1 2.7 2 0 0 2 2 2 0 RNase II-type exonuclease C-terminal S1 domain Abhydrolase_3 PF07859.13 KXS12807.1 - 4e-22 79.1 0.0 6.1e-22 78.5 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KXS12807.1 - 5.3e-16 58.4 0.0 1.1e-15 57.4 0.0 1.4 1 1 0 1 1 1 1 Steryl acetyl hydrolase SH3_9 PF14604.6 KXS12808.1 - 6.8e-07 29.1 0.0 1.1e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Ank_3 PF13606.6 KXS12808.1 - 3.1e-06 27.1 0.1 0.0053 17.1 0.0 3.4 4 0 0 4 4 2 1 Ankyrin repeat DUF3450 PF11932.8 KXS12808.1 - 2.7e-05 23.6 2.4 4.5e-05 22.9 2.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) Ank_4 PF13637.6 KXS12808.1 - 3e-05 24.5 0.0 0.6 10.8 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KXS12808.1 - 0.00014 22.2 0.5 0.068 13.7 0.1 3.5 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.7 KXS12808.1 - 0.00072 20.1 0.0 0.019 15.6 0.0 2.8 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) SH3_1 PF00018.28 KXS12808.1 - 0.0012 18.5 0.0 0.0021 17.6 0.0 1.5 1 0 0 1 1 1 1 SH3 domain Ank_5 PF13857.6 KXS12808.1 - 0.012 15.9 0.0 2 8.8 0.0 2.8 3 0 0 3 3 2 0 Ankyrin repeats (many copies) SH3_2 PF07653.17 KXS12808.1 - 0.091 12.5 0.0 0.22 11.2 0.0 1.6 1 1 0 1 1 1 0 Variant SH3 domain CEP209_CC5 PF16574.5 KXS12808.1 - 0.15 12.3 1.8 0.25 11.5 1.8 1.3 1 0 0 1 1 1 0 Coiled-coil region of centrosome protein CE290 FlxA PF14282.6 KXS12808.1 - 0.15 12.1 3.5 0.29 11.2 3.5 1.4 1 0 0 1 1 1 0 FlxA-like protein DivIC PF04977.15 KXS12808.1 - 0.31 10.8 9.9 0.64 9.8 1.9 2.6 2 1 1 3 3 2 0 Septum formation initiator GAS PF13851.6 KXS12808.1 - 0.32 10.3 5.5 0.48 9.8 5.5 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding CENP-F_N PF10481.9 KXS12808.1 - 0.33 10.5 3.5 0.26 10.9 1.6 1.7 2 0 0 2 2 2 0 Cenp-F N-terminal domain DUF4094 PF13334.6 KXS12808.1 - 0.35 11.3 2.5 0.68 10.4 1.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) APG6_N PF17675.1 KXS12808.1 - 1.1 9.8 8.8 1.8 9.1 8.8 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region Jnk-SapK_ap_N PF09744.9 KXS12808.1 - 1.6 9.0 6.1 2.7 8.2 6.1 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 ADIP PF11559.8 KXS12808.1 - 1.7 8.7 9.3 2.7 8.1 9.3 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding M PF02370.16 KXS12808.1 - 2 9.2 7.5 21 6.1 0.4 2.7 2 0 0 2 2 2 0 M protein repeat Cnn_1N PF07989.11 KXS12808.1 - 2.2 8.5 4.5 32 4.8 4.5 2.2 1 1 0 1 1 1 0 Centrosomin N-terminal motif 1 KfrA_N PF11740.8 KXS12808.1 - 3.4 8.4 16.2 88 3.8 11.1 3.1 2 1 0 2 2 2 0 Plasmid replication region DNA-binding N-term ZapB PF06005.12 KXS12808.1 - 6.3 7.3 9.1 13 6.3 9.1 1.5 1 0 0 1 1 1 0 Cell division protein ZapB bZIP_2 PF07716.15 KXS12808.1 - 6.5 6.9 9.5 4.5 7.4 2.9 2.3 1 1 1 2 2 2 0 Basic region leucine zipper IF3_N PF05198.16 KXS12809.1 - 8.4e-08 32.4 0.0 1.4e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 Translation initiation factor IF-3, N-terminal domain IF3_C PF00707.22 KXS12809.1 - 0.0096 15.9 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain ADH_zinc_N PF00107.26 KXS12811.1 - 8.9e-25 87.2 0.0 1.3e-24 86.6 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXS12811.1 - 9.7e-14 52.6 0.0 1.5e-13 52.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXS12811.1 - 1.9e-08 34.1 0.0 6e-08 32.5 0.0 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain zf-C2H2 PF00096.26 KXS12812.1 - 2.5e-13 49.7 20.9 0.00043 20.6 3.7 3.3 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KXS12812.1 - 2.3e-10 40.4 20.5 3.8e-05 23.9 0.9 4.2 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KXS12812.1 - 4.4e-08 33.3 20.4 0.0012 19.5 1.2 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KXS12812.1 - 0.00081 19.1 7.8 0.55 10.0 0.9 3.5 3 0 0 3 3 3 2 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 KXS12812.1 - 0.0027 17.9 1.4 12 6.3 0.0 3.4 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 KXS12812.1 - 0.0038 17.0 10.5 0.69 9.7 1.9 3.3 3 0 0 3 3 3 2 zinc-finger C2H2-type zf-C2H2_8 PF15909.5 KXS12812.1 - 0.005 17.1 5.2 0.0069 16.7 4.0 1.7 1 1 1 2 2 2 1 C2H2-type zinc ribbon FOXP-CC PF16159.5 KXS12812.1 - 0.025 15.2 5.1 2.1 9.0 1.2 2.5 2 0 0 2 2 2 0 FOXP coiled-coil domain IBR PF01485.21 KXS12812.1 - 0.13 12.5 7.3 0.71 10.2 4.1 2.2 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain zf_ZIC PF18366.1 KXS12812.1 - 0.14 12.3 5.7 2.2 8.5 0.2 3.1 1 1 2 3 3 3 0 Zic proteins zinc finger domain zf-met PF12874.7 KXS12812.1 - 3.7 8.1 6.3 37 4.9 0.0 3.5 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KXS12812.1 - 6.5 6.9 13.0 4.5 7.4 0.5 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger Fungal_trans PF04082.18 KXS12813.1 - 4.3e-17 62.0 0.0 6.6e-17 61.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXS12813.1 - 3.9e-09 36.5 10.5 7.7e-09 35.5 10.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Troponin-I_N PF11636.8 KXS12813.1 - 0.17 11.8 0.8 3.3 7.7 0.2 2.5 2 0 0 2 2 2 0 Troponin I residues 1-32 Putative_PNPOx PF01243.20 KXS12815.1 - 6.7e-25 87.1 0.0 1.2e-24 86.3 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase PNP_phzG_C PF10590.9 KXS12815.1 - 1.1e-20 73.4 1.3 2.7e-20 72.2 1.3 1.7 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxase_2 PF12766.7 KXS12815.1 - 1.3e-05 25.7 0.0 2.3e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Sel1 PF08238.12 KXS12816.1 - 2.1e-47 158.5 22.0 8.7e-07 29.4 0.3 10.7 10 1 0 10 10 10 9 Sel1 repeat TPR_16 PF13432.6 KXS12816.1 - 0.13 12.9 23.1 17 6.1 0.4 7.4 5 3 3 8 8 8 0 Tetratricopeptide repeat PPR PF01535.20 KXS12816.1 - 0.4 11.0 1.6 15 6.1 0.0 4.0 5 0 0 5 5 5 0 PPR repeat TPR_6 PF13174.6 KXS12816.1 - 1.7 9.5 16.1 24 5.8 0.9 6.5 7 1 0 7 7 7 0 Tetratricopeptide repeat WD40 PF00400.32 KXS12817.1 - 3.6e-36 122.6 21.9 1.3e-08 35.3 0.1 8.5 7 2 0 7 7 7 7 WD domain, G-beta repeat PRP4 PF08799.11 KXS12817.1 - 1.5e-14 53.3 1.9 3.3e-14 52.1 1.9 1.7 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like ANAPC4_WD40 PF12894.7 KXS12817.1 - 2.9e-12 46.7 0.1 0.0025 18.1 0.0 5.8 3 1 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KXS12817.1 - 0.00045 19.7 0.0 0.019 14.3 0.0 2.2 2 0 0 2 2 2 1 WD40-like domain Nup160 PF11715.8 KXS12817.1 - 0.01 14.5 0.2 0.054 12.1 0.0 2.3 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KXS12817.1 - 0.03 13.3 0.3 12 4.7 0.0 3.5 2 1 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein ADH_zinc_N PF00107.26 KXS12818.1 - 1.2e-20 73.8 0.0 1.8e-20 73.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXS12818.1 - 7.9e-15 56.1 0.0 1.5e-14 55.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXS12818.1 - 2.5e-09 37.0 0.0 4.5e-08 33.0 0.0 2.3 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Pyridoxal_deC PF00282.19 KXS12821.1 - 3.7e-30 104.9 0.0 2.4e-15 56.2 0.0 3.2 2 1 1 3 3 3 3 Pyridoxal-dependent decarboxylase conserved domain DUF1778 PF08681.11 KXS12821.1 - 0.042 13.8 0.4 1.2 9.1 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1778) CKAP2_C PF15297.6 KXS12821.1 - 0.25 10.4 0.0 0.25 10.4 0.0 1.5 2 0 0 2 2 2 0 Cytoskeleton-associated protein 2 C-terminus Methyltransf_21 PF05050.12 KXS12822.1 - 8.9e-05 22.6 0.0 8.9e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase FkbM domain PseudoU_synth_2 PF00849.22 KXS12823.1 - 3.6e-27 95.4 0.0 5.4e-27 94.8 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 KXS12823.1 - 0.0039 16.9 0.0 0.0099 15.6 0.0 1.7 1 0 0 1 1 1 1 S4 domain Ub-Mut7C PF14451.6 KXS12823.1 - 0.025 14.4 0.0 0.067 13.0 0.0 1.7 1 0 0 1 1 1 0 Mut7-C ubiquitin ThiS-like PF14453.6 KXS12823.1 - 0.045 13.8 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 ThiS-like ubiquitin Thymopoietin PF08198.11 KXS12824.1 - 6.7e-09 35.2 0.1 1.5e-08 34.1 0.1 1.6 1 0 0 1 1 1 1 Thymopoietin protein HeH PF12949.7 KXS12824.1 - 0.019 14.7 0.1 0.037 13.7 0.1 1.5 1 0 0 1 1 1 0 HeH/LEM domain Imm17 PF15562.6 KXS12824.1 - 0.066 13.1 0.1 0.16 11.9 0.1 1.6 1 0 0 1 1 1 0 Immunity protein 17 adh_short PF00106.25 KXS12825.1 - 5.3e-27 94.5 0.0 7e-27 94.2 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXS12825.1 - 2.6e-25 89.3 0.0 4.1e-25 88.7 0.0 1.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 3HCDH_N PF02737.18 KXS12825.1 - 0.00022 21.1 0.0 0.00032 20.6 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain KR PF08659.10 KXS12825.1 - 0.0021 18.0 0.0 0.0033 17.4 0.0 1.4 1 0 0 1 1 1 1 KR domain B12-binding PF02310.19 KXS12825.1 - 0.11 12.6 0.0 1.7 8.7 0.0 2.1 2 0 0 2 2 2 0 B12 binding domain NAD_binding_2 PF03446.15 KXS12825.1 - 0.14 12.4 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase EB PF01683.18 KXS12826.1 - 0.029 14.7 13.0 0.34 11.2 10.1 2.3 1 1 1 2 2 2 0 EB module IPTL-CTERM PF18203.1 KXS12826.1 - 0.036 14.0 2.0 0.072 13.0 2.0 1.5 1 0 0 1 1 1 0 IPTL-CTERM motif TMEM154 PF15102.6 KXS12826.1 - 0.24 11.3 0.9 0.57 10.1 0.1 1.8 1 1 1 2 2 2 0 TMEM154 protein family LisH PF08513.11 KXS12827.1 - 0.0033 17.3 0.0 0.0061 16.5 0.0 1.5 1 0 0 1 1 1 1 LisH LRRFIP PF09738.9 KXS12827.1 - 0.6 9.5 3.4 0.24 10.8 0.1 1.8 2 0 0 2 2 2 0 LRRFIP family BRD4_CDT PF17105.5 KXS12827.1 - 0.75 9.4 6.0 1.5 8.5 6.0 1.5 1 0 0 1 1 1 0 C-terminal domain of bromodomain protein 4 FYVE PF01363.21 KXS12828.1 - 5.7e-10 39.2 2.0 1e-09 38.4 2.0 1.4 1 0 0 1 1 1 1 FYVE zinc finger DHR10 PF18595.1 KXS12828.1 - 0.012 15.6 16.5 0.35 10.9 3.2 2.8 2 1 1 3 3 3 0 Designed helical repeat protein 10 domain zf-AN1 PF01428.16 KXS12828.1 - 0.04 14.1 4.6 0.08 13.1 4.6 1.5 1 0 0 1 1 1 0 AN1-like Zinc finger FemAB PF02388.16 KXS12828.1 - 0.13 11.1 0.5 0.21 10.4 0.5 1.2 1 0 0 1 1 1 0 FemAB family TBCC_N PF16752.5 KXS12828.1 - 0.16 12.5 9.1 2.4 8.6 0.2 3.1 1 1 2 3 3 3 0 Tubulin-specific chaperone C N-terminal domain CENP-F_leu_zip PF10473.9 KXS12828.1 - 0.2 11.7 12.5 1.4 8.9 5.2 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SKA1 PF07160.12 KXS12828.1 - 0.23 11.3 5.0 0.41 10.5 1.3 2.1 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 FliJ PF02050.16 KXS12828.1 - 0.52 10.5 10.1 0.73 10.1 3.2 2.4 1 1 1 2 2 2 0 Flagellar FliJ protein GAS PF13851.6 KXS12828.1 - 0.54 9.6 9.0 0.54 9.6 7.9 1.5 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DivIVA PF05103.13 KXS12828.1 - 0.72 9.9 7.5 1.3 9.1 7.5 1.4 1 0 0 1 1 1 0 DivIVA protein CC2-LZ PF16516.5 KXS12828.1 - 0.89 10.0 6.8 0.59 10.5 2.3 2.3 1 1 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DUF1043 PF06295.12 KXS12828.1 - 2.3 8.2 5.6 4.4 7.3 4.6 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1043) Sec2p PF06428.11 KXS12828.1 - 2.6 8.1 13.6 4.4 7.3 4.0 3.4 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p Pox_A_type_inc PF04508.12 KXS12828.1 - 2.7 8.0 7.4 0.26 11.2 0.6 3.0 3 0 0 3 3 2 0 Viral A-type inclusion protein repeat Rho_Binding PF08912.11 KXS12828.1 - 2.7 8.9 7.7 0.56 11.1 3.0 2.2 2 1 0 2 2 2 0 Rho Binding UPF0242 PF06785.11 KXS12828.1 - 2.8 8.0 11.0 1.9 8.6 8.9 1.6 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus APG6_N PF17675.1 KXS12828.1 - 5.5 7.5 15.8 1.1 9.8 9.3 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region Fez1 PF06818.15 KXS12828.1 - 9.1 6.7 12.4 22 5.4 12.4 1.6 1 1 0 1 1 1 0 Fez1 DUF3808 PF10300.9 KXS12829.1 - 5e-80 269.6 0.0 2.2e-40 138.8 0.0 2.5 2 1 0 2 2 2 2 Protein of unknown function (DUF3808) TPR_16 PF13432.6 KXS12829.1 - 5.3e-06 27.0 5.9 0.015 15.9 0.1 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KXS12829.1 - 5.2e-05 23.0 8.3 0.51 10.6 0.2 5.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 KXS12829.1 - 0.00035 21.0 1.5 3.3 8.3 0.1 4.4 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 KXS12829.1 - 0.0012 19.4 2.5 6.9 7.5 0.0 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 KXS12829.1 - 0.024 14.7 0.5 9 6.6 0.2 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 KXS12829.1 - 0.55 10.6 1.6 2.9 8.3 0.2 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KXS12829.1 - 0.9 10.5 5.5 97 4.2 0.0 5.1 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.6 KXS12829.1 - 1.6 9.1 4.1 39 4.6 1.0 4.1 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 KXS12829.1 - 4.3 7.3 6.6 69 3.5 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 KXS12829.1 - 5.5 7.9 5.8 92 4.1 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat O-FucT PF10250.9 KXS12830.1 - 8.4e-15 55.3 0.0 1.5e-14 54.5 0.0 1.3 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase RasGAP PF00616.19 KXS12830.1 - 0.056 13.1 0.3 0.092 12.4 0.3 1.2 1 0 0 1 1 1 0 GTPase-activator protein for Ras-like GTPase MukE PF04288.13 KXS12831.1 - 0.12 11.4 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 MukE-like family Peptidase_M20 PF01546.28 KXS12832.1 - 1.9e-29 102.9 0.5 2.3e-29 102.6 0.5 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KXS12832.1 - 8.9e-12 44.9 0.4 1.6e-11 44.1 0.4 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Read-through PF16814.5 KXS12832.1 - 0.18 11.6 0.0 0.34 10.7 0.0 1.4 1 0 0 1 1 1 0 Read-through domain Spb1_C PF07780.12 KXS12833.1 - 3.1e-64 216.5 14.6 3.1e-64 216.5 14.6 3.5 5 0 0 5 5 5 1 Spb1 C-terminal domain FtsJ PF01728.19 KXS12833.1 - 3.1e-54 183.8 0.1 8.6e-54 182.3 0.0 1.8 2 0 0 2 2 2 1 FtsJ-like methyltransferase DUF3381 PF11861.8 KXS12833.1 - 6.5e-34 117.1 0.7 6.5e-34 117.1 0.7 5.7 4 1 2 6 6 6 1 Domain of unknown function (DUF3381) HhH-GPD PF00730.25 KXS12833.1 - 0.085 13.3 1.8 27 5.2 0.0 3.5 3 0 0 3 3 3 0 HhH-GPD superfamily base excision DNA repair protein Pet100 PF09803.9 KXS12834.1 - 0.12 12.9 0.0 0.21 12.1 0.0 1.3 1 0 0 1 1 1 0 Pet100 ARS2 PF04959.13 KXS12834.1 - 1.4 9.3 4.8 1.7 8.9 4.5 1.3 1 1 0 1 1 1 0 Arsenite-resistance protein 2 UQ_con PF00179.26 KXS12839.1 - 3e-10 39.9 0.0 5.8e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme CTP_transf_like PF01467.26 KXS12840.1 - 0.00056 20.1 0.0 0.0011 19.1 0.0 1.5 1 0 0 1 1 1 1 Cytidylyltransferase-like Aldo_ket_red PF00248.21 KXS12841.1 - 8.1e-72 241.9 0.1 1e-71 241.5 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Mito_carr PF00153.27 KXS12842.1 - 7.7e-64 211.7 1.2 3.4e-22 78.2 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein HCV_NS5a_1a PF08300.13 KXS12842.1 - 0.13 12.4 0.2 1 9.5 0.1 2.5 3 0 0 3 3 3 0 Hepatitis C virus non-structural 5a zinc finger domain zf-RING_2 PF13639.6 KXS12844.1 - 7.7e-13 48.6 4.4 1.4e-12 47.7 4.4 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KXS12844.1 - 8.9e-11 41.3 1.2 2.1e-10 40.1 1.2 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KXS12844.1 - 9.1e-09 35.0 3.3 1.7e-08 34.1 3.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXS12844.1 - 3.1e-08 33.3 1.4 5e-08 32.7 1.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PA PF02225.22 KXS12844.1 - 5.2e-07 29.6 0.0 1.3e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 PA domain zf-rbx1 PF12678.7 KXS12844.1 - 1e-06 28.9 4.6 3.9e-06 27.0 4.6 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KXS12844.1 - 1.4e-06 28.2 1.3 3.7e-06 26.9 0.3 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 KXS12844.1 - 1.7e-06 27.9 1.4 2.7e-06 27.2 1.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KXS12844.1 - 6.6e-05 22.7 1.4 0.00012 21.9 1.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KXS12844.1 - 0.011 15.3 1.6 0.019 14.6 1.6 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 KXS12844.1 - 0.012 15.6 2.4 0.037 14.1 2.4 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 KXS12844.1 - 0.024 14.5 2.8 0.06 13.2 2.8 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 KXS12844.1 - 0.038 13.8 4.2 0.077 12.8 4.2 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 KXS12844.1 - 0.043 14.0 1.0 0.18 12.0 1.1 2.1 2 0 0 2 2 2 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.6 KXS12844.1 - 0.13 12.4 2.9 0.27 11.4 2.9 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING PHD PF00628.29 KXS12844.1 - 0.5 10.3 1.9 0.9 9.5 1.9 1.4 1 0 0 1 1 1 0 PHD-finger RINGv PF12906.7 KXS12844.1 - 3.9 7.7 4.8 2.5 8.3 2.6 1.9 2 0 0 2 2 1 0 RING-variant domain DUF2256 PF10013.9 KXS12844.1 - 4.5 7.5 6.2 1.2 9.3 3.1 1.7 2 0 0 2 2 1 0 Uncharacterized protein conserved in bacteria (DUF2256) HAD PF12710.7 KXS12845.1 - 1.6e-08 35.1 0.0 2.8e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KXS12845.1 - 0.014 15.6 0.1 1.3 9.3 0.0 2.3 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.12 KXS12845.1 - 0.13 11.8 0.1 0.21 11.0 0.1 1.6 1 1 0 1 1 1 0 Pyrimidine 5'-nucleotidase (UMPH-1) MFS_1 PF07690.16 KXS12846.1 - 1.2e-20 73.7 11.9 1.1e-18 67.3 6.9 2.8 2 1 0 2 2 2 2 Major Facilitator Superfamily DUF5079 PF16882.5 KXS12846.1 - 0.065 13.1 0.1 0.11 12.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5079) MFS_1_like PF12832.7 KXS12846.1 - 4.8 5.9 13.3 9.9 4.9 7.6 3.5 2 1 0 2 2 2 0 MFS_1 like family adh_short PF00106.25 KXS12847.1 - 1.9e-26 92.8 0.0 2.3e-19 69.6 0.0 2.0 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXS12847.1 - 2.5e-15 56.7 0.0 3.4e-13 49.7 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXS12847.1 - 2.7e-05 24.2 0.0 4.4e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXS12847.1 - 0.15 11.5 0.0 0.94 8.9 0.0 1.8 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family adh_short PF00106.25 KXS12848.1 - 5.1e-27 94.6 0.2 1.4e-25 89.9 0.2 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXS12848.1 - 3.5e-17 62.8 0.2 5.2e-15 55.6 0.2 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXS12848.1 - 2.3e-06 27.6 0.1 3.7e-06 27.0 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXS12848.1 - 0.088 12.2 0.1 0.36 10.3 0.1 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 KXS12848.1 - 0.091 12.1 0.1 1.4 8.2 0.0 2.2 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain FtsX PF02687.21 KXS12849.1 - 0.27 11.7 1.6 0.36 11.3 1.6 1.1 1 0 0 1 1 1 0 FtsX-like permease family MFS_1 PF07690.16 KXS12850.1 - 5e-29 101.3 34.9 9.3e-29 100.4 33.6 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF2070 PF09843.9 KXS12850.1 - 0.2 9.9 8.0 0.31 9.3 8.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) YrhC PF14143.6 KXS12850.1 - 5.7 7.1 6.5 4.5 7.4 0.1 3.5 3 1 0 3 3 3 0 YrhC-like protein zf-RING_2 PF13639.6 KXS12851.1 - 6.5e-12 45.6 6.5 1.1e-11 44.9 6.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KXS12851.1 - 5.5e-08 32.5 5.3 9.4e-08 31.8 5.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KXS12851.1 - 1.5e-07 31.6 6.6 2.9e-07 30.7 5.8 1.9 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 KXS12851.1 - 1.6e-07 30.9 4.4 3.2e-07 30.0 4.4 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 KXS12851.1 - 5.5e-07 29.4 2.7 9.4e-07 28.6 2.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXS12851.1 - 4.7e-06 26.5 2.4 1.9e-05 24.6 2.8 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KXS12851.1 - 0.00015 21.5 3.0 0.00025 20.8 3.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXS12851.1 - 0.00025 20.9 3.1 0.00034 20.5 2.2 1.7 2 0 0 2 2 2 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 KXS12851.1 - 0.0019 18.2 3.1 0.0042 17.1 3.1 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 KXS12851.1 - 0.0031 17.3 3.1 0.0078 16.1 3.1 1.7 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KXS12851.1 - 0.0085 16.2 5.8 0.015 15.4 5.8 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 KXS12851.1 - 0.093 12.5 3.3 0.15 11.9 3.3 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Zn_ribbon_17 PF17120.5 KXS12851.1 - 0.27 10.9 6.6 0.66 9.7 6.6 1.7 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3H2C3 PF17122.5 KXS12851.1 - 0.57 10.3 4.1 1.4 9.1 4.1 1.7 1 1 0 1 1 1 0 Zinc-finger FANCL_C PF11793.8 KXS12851.1 - 0.88 9.8 4.7 5.3 7.3 4.7 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain Ndc1_Nup PF09531.10 KXS12852.1 - 2 7.0 5.2 3 6.4 5.2 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RRM_1 PF00076.22 KXS12854.1 - 0.00023 20.9 0.0 0.00047 19.9 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF5614 PF18474.1 KXS12856.1 - 0.093 12.0 0.0 0.29 10.4 0.0 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5614) LRR_8 PF13855.6 KXS12858.1 - 9e-09 35.0 7.6 8e-06 25.5 1.6 2.4 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KXS12858.1 - 8.6e-06 26.0 3.2 0.0019 18.5 1.0 2.7 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KXS12858.1 - 0.0013 18.6 1.4 1.3 9.3 0.2 2.8 2 0 0 2 2 2 2 Leucine Rich repeat SH3_1 PF00018.28 KXS12858.1 - 0.0053 16.3 0.0 0.009 15.6 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KXS12858.1 - 0.0053 16.6 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain LRR_9 PF14580.6 KXS12858.1 - 0.019 14.5 0.0 0.045 13.3 0.0 1.5 1 1 1 2 2 2 0 Leucine-rich repeat LRR_1 PF00560.33 KXS12858.1 - 0.18 12.5 2.7 10 7.1 0.1 3.9 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_8 PF13855.6 KXS12859.1 - 4.3e-18 64.8 13.7 1.1e-10 41.1 4.4 4.6 3 2 1 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 KXS12859.1 - 2.5e-13 50.0 16.0 0.0025 18.2 0.0 5.5 4 2 4 8 8 8 6 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KXS12859.1 - 7.6e-08 32.1 1.4 6.5e-05 22.5 0.0 2.4 2 0 0 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.6 KXS12859.1 - 0.00022 21.0 21.0 5.7 7.3 1.0 7.6 8 0 0 8 8 8 3 Leucine Rich repeat LRR_1 PF00560.33 KXS12859.1 - 0.018 15.5 19.7 24 6.0 0.8 7.4 6 1 1 7 7 7 0 Leucine Rich Repeat DUF5092 PF17010.5 KXS12860.1 - 1.3e-32 113.0 0.0 1.6e-25 89.9 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF5092) B3 PF02362.21 KXS12860.1 - 0.015 15.1 0.0 0.03 14.2 0.0 1.4 1 0 0 1 1 1 0 B3 DNA binding domain S_4TM PF18159.1 KXS12860.1 - 1.5 8.1 3.7 2.1 7.6 3.7 1.1 1 0 0 1 1 1 0 SMODS-associating 4TM effector domain FA_desaturase PF00487.24 KXS12861.1 - 2e-24 86.8 15.0 2e-24 86.8 15.0 1.9 1 1 1 2 2 2 2 Fatty acid desaturase Lipid_DES PF08557.10 KXS12861.1 - 2.5e-16 58.8 0.2 4.2e-16 58.2 0.2 1.4 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) Thiolase_N PF00108.23 KXS12862.1 - 4.8e-88 294.9 2.1 9e-83 277.6 2.9 2.4 1 1 1 2 2 2 2 Thiolase, N-terminal domain Thiolase_C PF02803.18 KXS12862.1 - 2e-38 130.8 0.3 4.5e-38 129.7 0.3 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain Lipid_DES PF08557.10 KXS12862.1 - 5.8e-16 57.7 0.2 1.1e-15 56.8 0.2 1.5 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) FA_desaturase PF00487.24 KXS12862.1 - 3.5e-15 56.5 6.1 3.5e-15 56.5 6.1 2.7 2 1 1 3 3 3 2 Fatty acid desaturase ketoacyl-synt PF00109.26 KXS12862.1 - 2.7e-05 23.9 2.5 8e-05 22.3 0.6 2.5 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain Methyltransf_25 PF13649.6 KXS12863.1 - 1.5e-13 51.2 0.1 2.7e-13 50.4 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXS12863.1 - 6.4e-11 42.8 0.1 9.8e-11 42.2 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXS12863.1 - 5.7e-09 36.6 0.0 8.4e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXS12863.1 - 1.5e-07 31.4 0.0 2.5e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXS12863.1 - 1.3e-05 25.0 0.0 1.8e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KXS12863.1 - 1.9e-05 24.1 0.0 2.5e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase TehB PF03848.14 KXS12863.1 - 0.042 13.3 0.0 0.086 12.2 0.0 1.5 2 0 0 2 2 2 0 Tellurite resistance protein TehB PrmA PF06325.13 KXS12863.1 - 0.06 12.7 0.0 0.086 12.2 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_15 PF09445.10 KXS12863.1 - 0.13 11.8 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase CPBP PF02517.16 KXS12864.1 - 8.2e-05 22.9 4.8 8.2e-05 22.9 4.8 2.3 2 1 1 3 3 3 1 CPBP intramembrane metalloprotease Fungal_trans PF04082.18 KXS12865.1 - 3.1e-09 36.2 0.2 5.4e-09 35.5 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF1639 PF07797.14 KXS12865.1 - 0.2 11.7 0.0 0.39 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1639) PRIMA1 PF16101.5 KXS12866.1 - 0.66 10.0 2.8 1.1 9.3 2.8 1.3 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Fungal_trans PF04082.18 KXS12867.1 - 4.8e-08 32.3 1.9 4.7e-07 29.1 1.9 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_61 PF03443.14 KXS12868.1 - 3.4e-45 154.5 0.1 4.8e-45 154.0 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.18 KXS12868.1 - 2.2e-10 40.3 10.6 6.3e-10 38.9 10.6 1.9 1 0 0 1 1 1 1 Fungal cellulose binding domain SH3_3 PF08239.11 KXS12868.1 - 0.12 12.7 0.0 0.26 11.6 0.0 1.6 1 1 0 1 1 1 0 Bacterial SH3 domain SH3_9 PF14604.6 KXS12869.1 - 2.7e-05 23.9 0.0 0.00015 21.6 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain Ank_3 PF13606.6 KXS12869.1 - 4.6e-05 23.5 0.1 0.13 12.9 0.0 4.4 4 0 0 4 4 4 1 Ankyrin repeat Ank PF00023.30 KXS12869.1 - 0.00015 22.0 0.4 4.6 7.9 0.0 4.4 4 0 0 4 4 4 1 Ankyrin repeat SH3_1 PF00018.28 KXS12869.1 - 0.01 15.4 0.0 0.019 14.6 0.0 1.4 1 0 0 1 1 1 0 SH3 domain Ank_4 PF13637.6 KXS12869.1 - 0.015 15.8 0.0 1.9 9.1 0.0 3.4 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXS12869.1 - 0.027 14.8 0.3 19 5.7 0.0 3.4 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXS12869.1 - 0.064 13.8 0.2 8.3 7.1 0.0 3.1 2 1 1 3 3 3 0 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXS12870.1 - 0.00023 21.4 0.0 0.00078 19.7 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.7 KXS12870.1 - 0.00092 19.8 0.0 0.12 12.9 0.0 2.0 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXS12870.1 - 0.0021 18.6 0.0 0.012 16.2 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXS12870.1 - 0.019 15.3 0.0 0.051 13.9 0.0 1.7 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank PF00023.30 KXS12870.1 - 0.15 12.6 0.0 0.9 10.1 0.0 2.0 2 0 0 2 2 2 0 Ankyrin repeat Ank_3 PF13606.6 KXS12871.1 - 6.6e-11 41.5 0.6 0.013 15.9 0.0 5.6 6 0 0 6 6 6 2 Ankyrin repeat Ank_2 PF12796.7 KXS12871.1 - 9.6e-11 42.1 0.0 0.00076 20.0 0.0 3.9 3 2 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXS12871.1 - 1.1e-09 38.3 0.1 0.011 16.0 0.0 3.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KXS12871.1 - 5.1e-09 36.2 0.2 0.014 15.8 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat SH3_9 PF14604.6 KXS12871.1 - 5.9e-07 29.2 0.1 1.2e-06 28.2 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain Ank_4 PF13637.6 KXS12871.1 - 2.3e-05 24.9 0.0 5.8 7.6 0.0 5.3 5 1 1 6 6 6 1 Ankyrin repeats (many copies) SH3_1 PF00018.28 KXS12871.1 - 0.00012 21.7 0.0 0.00021 20.8 0.0 1.4 1 0 0 1 1 1 1 SH3 domain EzrA PF06160.12 KXS12871.1 - 0.1 10.8 1.8 0.15 10.2 1.8 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Cluap1 PF10234.9 KXS12871.1 - 0.24 10.8 3.2 0.4 10.0 3.2 1.3 1 0 0 1 1 1 0 Clusterin-associated protein-1 Chs7 PF12271.8 KXS12872.1 - 2e-100 335.9 14.9 2.3e-100 335.7 14.9 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone DUF4491 PF14898.6 KXS12872.1 - 4.2 7.9 9.5 0.31 11.5 0.5 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4491) SH3_9 PF14604.6 KXS12873.1 - 8.4e-05 22.4 5.5 8.5e-05 22.3 2.6 2.5 2 1 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 KXS12873.1 - 0.015 14.9 0.1 0.05 13.2 0.1 1.9 1 1 0 1 1 1 0 SH3 domain SH3_4 PF06347.13 KXS12873.1 - 0.11 12.3 1.1 0.32 10.9 1.1 1.7 1 0 0 1 1 1 0 Bacterial SH3 domain SH3_2 PF07653.17 KXS12873.1 - 0.15 11.7 0.5 0.36 10.5 0.5 1.6 1 0 0 1 1 1 0 Variant SH3 domain Arylsulfotran_2 PF14269.6 KXS12874.1 - 1.4e-32 113.3 0.0 2.4e-25 89.5 0.1 2.1 1 1 1 2 2 2 2 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KXS12874.1 - 2.4e-07 30.0 0.0 3.3e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Ig_3 PF13927.6 KXS12874.1 - 0.069 13.8 0.1 1.2 9.8 0.0 2.3 2 0 0 2 2 2 0 Immunoglobulin domain Prenyltrans PF00432.21 KXS12875.1 - 1.7e-62 206.8 13.2 9.9e-12 44.4 0.2 6.2 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 KXS12875.1 - 0.00067 18.9 0.0 0.41 9.7 0.0 3.7 2 2 1 4 4 4 2 Squalene-hopene cyclase N-terminal domain SH3_9 PF14604.6 KXS12876.1 - 5e-05 23.1 0.1 8.7e-05 22.3 0.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXS12876.1 - 0.0052 16.4 0.2 0.0073 15.9 0.2 1.2 1 0 0 1 1 1 1 SH3 domain MFS_1 PF07690.16 KXS12877.1 - 5.8e-46 157.0 26.8 5.8e-46 157.0 26.8 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXS12877.1 - 2.7e-12 46.3 27.0 4.7e-12 45.5 5.3 3.3 2 1 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 KXS12877.1 - 0.00011 20.8 2.6 0.00011 20.8 2.6 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF2371 PF10177.9 KXS12877.1 - 0.013 15.7 1.5 5.7 7.1 0.1 3.7 4 0 0 4 4 4 0 Uncharacterised conserved protein (DUF2371) LapA_dom PF06305.11 KXS12877.1 - 0.93 9.4 0.0 0.93 9.4 0.0 3.4 4 0 0 4 4 4 0 Lipopolysaccharide assembly protein A domain OATP PF03137.20 KXS12877.1 - 2.2 6.5 9.1 0.55 8.4 0.9 3.0 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family DUF3285 PF11688.8 KXS12877.1 - 4.8 7.2 5.2 4.7 7.2 0.8 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3285) Sua5_yciO_yrdC PF01300.18 KXS12879.1 - 1.1e-47 161.9 0.0 6.5e-30 104.0 0.0 2.2 2 0 0 2 2 2 2 Telomere recombination SUA5 PF03481.13 KXS12879.1 - 3.2e-21 76.3 0.0 6e-21 75.4 0.0 1.5 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding La PF05383.17 KXS12880.1 - 4.4e-14 52.3 0.0 7.5e-14 51.5 0.0 1.4 1 0 0 1 1 1 1 La domain PBP5_C PF07943.13 KXS12882.1 - 0.012 15.8 4.7 0.012 15.8 4.7 2.1 2 0 0 2 2 2 0 Penicillin-binding protein 5, C-terminal domain DGF-1_C PF11040.8 KXS12882.1 - 0.11 12.5 0.3 0.11 12.5 0.3 2.5 1 1 0 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus Ank_4 PF13637.6 KXS12883.1 - 2.5e-13 50.3 0.6 0.0013 19.3 0.0 4.6 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXS12883.1 - 7.8e-13 48.4 1.3 0.0054 17.0 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXS12883.1 - 2.3e-06 28.1 0.1 0.11 13.1 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 KXS12883.1 - 1.5e-05 25.2 5.1 1.2 9.7 0.1 5.2 5 1 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.6 KXS12883.1 - 0.00018 21.6 0.9 11 6.9 0.0 4.4 5 0 0 5 5 5 2 Ankyrin repeat La PF05383.17 KXS12885.1 - 1e-23 83.1 0.1 2.7e-23 81.8 0.1 1.8 1 0 0 1 1 1 1 La domain RRM_3 PF08777.11 KXS12885.1 - 5.7e-07 29.5 0.0 0.016 15.2 0.0 3.4 2 0 0 2 2 2 2 RNA binding motif La PF05383.17 KXS12886.1 - 1.1e-17 63.8 0.0 1.9e-17 63.1 0.0 1.4 1 0 0 1 1 1 1 La domain p450 PF00067.22 KXS12887.1 - 0.0064 15.3 0.0 0.0074 15.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_S9 PF00326.21 KXS12888.1 - 2.2e-37 128.6 0.0 4e-37 127.8 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S9_N PF02897.15 KXS12888.1 - 1.8e-27 96.2 0.0 4e-27 95.1 0.0 1.4 1 1 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Hydrolase_4 PF12146.8 KXS12888.1 - 0.19 11.0 0.0 0.89 8.8 0.0 1.9 1 1 1 2 2 2 0 Serine aminopeptidase, S33 Aconitase PF00330.20 KXS12889.1 - 9.9e-161 535.8 0.2 1.2e-160 535.5 0.2 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KXS12889.1 - 1.4e-38 132.2 0.0 2.6e-38 131.3 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain Kdo PF06293.14 KXS12890.1 - 1.6e-06 27.6 0.0 2.2e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXS12890.1 - 4.5e-06 26.8 1.0 0.08 12.9 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase PF00069.25 KXS12890.1 - 2e-05 24.1 0.0 3.3e-05 23.4 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 KXS12890.1 - 0.001 18.7 0.0 0.0016 18.1 0.0 1.3 1 1 0 1 1 1 1 RIO1 family WaaY PF06176.11 KXS12890.1 - 0.02 14.5 0.0 0.032 13.8 0.0 1.4 1 1 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) ESSS PF10183.9 KXS12890.1 - 0.02 15.1 0.1 0.049 13.9 0.1 1.6 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Choline_kinase PF01633.20 KXS12890.1 - 0.03 13.9 0.0 0.12 12.0 0.0 1.8 1 1 1 2 2 2 0 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 KXS12890.1 - 0.045 12.5 0.0 0.053 12.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Chorion_2 PF03964.15 KXS12890.1 - 1.1 10.1 5.2 1.9 9.4 4.8 1.6 1 1 1 2 2 2 0 Chorion family 2 Sel1 PF08238.12 KXS12891.1 - 5.2e-35 119.1 26.9 4.8e-06 27.1 2.4 8.0 8 1 0 8 8 8 7 Sel1 repeat TPR_2 PF07719.17 KXS12891.1 - 2.4e-05 24.1 13.5 1.2 9.5 0.0 7.2 7 1 1 8 8 8 2 Tetratricopeptide repeat TPR_16 PF13432.6 KXS12891.1 - 0.00011 22.7 10.8 0.85 10.3 0.0 5.4 3 1 3 6 6 6 3 Tetratricopeptide repeat Pkinase_Tyr PF07714.17 KXS12891.1 - 0.00034 20.0 0.0 0.00057 19.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase TPR_14 PF13428.6 KXS12891.1 - 0.0051 17.5 5.0 3.1 8.8 0.0 5.2 5 2 2 7 7 7 1 Tetratricopeptide repeat TPR_1 PF00515.28 KXS12891.1 - 0.041 13.7 13.8 2.1 8.3 0.0 6.4 7 1 0 7 7 7 0 Tetratricopeptide repeat Glyoxalase PF00903.25 KXS12891.1 - 0.088 13.0 0.6 0.95 9.7 0.6 2.6 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily TPR_11 PF13414.6 KXS12891.1 - 0.27 11.0 10.3 4.4 7.1 0.1 5.5 7 0 0 7 7 7 0 TPR repeat TPR_8 PF13181.6 KXS12891.1 - 7.7 7.0 0.0 7.7 7.0 0.0 5.4 7 1 0 7 7 7 0 Tetratricopeptide repeat LRR_6 PF13516.6 KXS12892.1 - 1.2e-28 96.7 30.1 1.7e-06 27.6 0.3 7.2 7 0 0 7 7 7 6 Leucine Rich repeat LRR_4 PF12799.7 KXS12892.1 - 1.4e-09 38.0 13.7 0.0082 16.5 0.2 3.7 3 2 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KXS12892.1 - 3e-07 30.0 0.2 15 6.6 0.0 6.0 6 0 0 6 6 6 1 Leucine Rich Repeat LRR_8 PF13855.6 KXS12892.1 - 0.0044 16.7 21.2 1.6 8.5 1.4 5.2 1 1 5 6 6 6 5 Leucine rich repeat YwqJ-deaminase PF14431.6 KXS12892.1 - 0.0049 17.0 0.3 3.6 7.8 0.1 3.6 1 1 3 4 4 4 2 YwqJ-like deaminase HOASN PF14515.6 KXS12892.1 - 0.051 14.0 3.4 15 6.0 0.0 4.0 1 1 2 4 4 4 0 Haem-oxygenase-associated N-terminal helices YusW PF14039.6 KXS12892.1 - 0.066 13.7 1.1 25 5.5 0.1 3.0 2 1 1 3 3 3 0 YusW-like protein SpoU_sub_bind PF08032.12 KXS12892.1 - 0.092 13.0 4.4 0.61 10.4 0.0 3.2 4 1 1 5 5 5 0 RNA 2'-O ribose methyltransferase substrate binding Put_DNA-bind_N PF06971.13 KXS12892.1 - 0.42 10.7 4.2 18 5.5 0.1 4.0 6 0 0 6 6 6 0 Putative DNA-binding protein N-terminus Arm-DNA-bind_1 PF09003.10 KXS12892.1 - 2.9 8.1 9.3 9.1 6.5 0.2 4.5 2 2 3 5 5 5 0 Bacteriophage lambda integrase, Arm DNA-binding domain p450 PF00067.22 KXS12893.1 - 2e-33 115.8 0.3 2e-20 73.0 0.1 2.0 2 0 0 2 2 2 2 Cytochrome P450 Glyco_hydro_28 PF00295.17 KXS12895.1 - 2.8e-50 171.2 3.8 4.1e-50 170.7 3.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Lectin_legB PF00139.19 KXS12896.1 - 8.7e-17 61.5 0.0 1.5e-16 60.7 0.0 1.3 1 0 0 1 1 1 1 Legume lectin domain Bact_lectin PF18483.1 KXS12896.1 - 3.6e-15 56.5 0.0 7.4e-15 55.5 0.0 1.5 1 1 0 1 1 1 1 Bacterial lectin PLDc_N PF13396.6 KXS12898.1 - 0.13 12.2 2.7 0.24 11.3 2.7 1.4 1 0 0 1 1 1 0 Phospholipase_D-nuclease N-terminal F-box-like PF12937.7 KXS12900.1 - 3.3e-06 26.9 0.0 7.7e-06 25.7 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXS12900.1 - 0.001 18.9 1.8 0.0044 16.9 0.3 2.5 2 0 0 2 2 2 1 F-box domain Dehydrin PF00257.19 KXS12900.1 - 0.59 10.7 1.5 0.94 10.0 1.5 1.2 1 0 0 1 1 1 0 Dehydrin Form_Nir_trans PF01226.17 KXS12901.1 - 3.4e-67 226.2 18.6 4.4e-67 225.9 18.6 1.1 1 0 0 1 1 1 1 Formate/nitrite transporter Histone_H2A_C PF16211.5 KXS12902.1 - 8.2e-20 70.3 1.4 1.4e-19 69.5 1.4 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KXS12902.1 - 4.4e-16 59.4 0.0 4.9e-16 59.3 0.0 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KXS12902.1 - 3.6e-06 27.2 0.0 4.6e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KXS12903.1 - 8.9e-22 77.9 0.8 1.1e-21 77.6 0.8 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KXS12903.1 - 5.5e-05 23.4 0.0 0.00014 22.0 0.0 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KXS12903.1 - 0.0026 18.2 0.0 0.0044 17.5 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A RP-C PF03428.13 KXS12903.1 - 0.085 12.5 0.1 0.22 11.2 0.1 1.6 1 1 0 1 1 1 0 Replication protein C N-terminal domain EAF PF09816.9 KXS12904.1 - 3.1e-05 24.3 0.0 7.5e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor SRP-alpha_N PF04086.13 KXS12904.1 - 8.2 6.3 8.4 0.47 10.3 2.2 1.8 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal AA_permease_2 PF13520.6 KXS12905.1 - 1.8e-48 165.4 40.1 2.5e-48 165.0 40.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXS12905.1 - 7e-22 77.7 37.2 9.5e-22 77.2 37.2 1.1 1 0 0 1 1 1 1 Amino acid permease LapA_dom PF06305.11 KXS12905.1 - 0.0026 17.5 1.9 0.098 12.5 0.1 3.5 2 0 0 2 2 2 1 Lipopolysaccharide assembly protein A domain DIOX_N PF14226.6 KXS12906.1 - 8e-23 81.4 0.0 1.7e-22 80.4 0.0 1.6 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KXS12906.1 - 7.6e-20 71.3 0.0 1.6e-19 70.3 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ABC_membrane PF00664.23 KXS12907.1 - 6.3e-98 327.8 23.7 4.8e-49 167.5 9.5 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KXS12907.1 - 1.9e-68 229.2 0.3 8.1e-35 120.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KXS12907.1 - 2.4e-11 43.5 5.2 5.6e-05 22.7 0.0 4.2 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KXS12907.1 - 2e-07 31.3 0.7 0.0061 16.8 0.1 3.6 2 2 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 KXS12907.1 - 1.3e-06 27.8 0.9 0.021 14.1 0.0 3.1 3 0 0 3 3 3 2 Zeta toxin RsgA_GTPase PF03193.16 KXS12907.1 - 2e-06 27.8 0.5 0.0074 16.2 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 KXS12907.1 - 2.3e-06 27.2 3.0 0.042 13.6 0.2 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KXS12907.1 - 2.3e-06 28.1 4.1 0.056 13.8 0.6 3.4 2 2 0 2 2 2 2 AAA ATPase domain AAA PF00004.29 KXS12907.1 - 3e-06 27.7 0.1 0.051 14.0 0.0 3.9 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.20 KXS12907.1 - 2.8e-05 24.1 0.2 0.056 13.3 0.1 2.6 2 0 0 2 2 2 2 Adenylylsulphate kinase AAA_21 PF13304.6 KXS12907.1 - 0.00012 22.0 1.3 0.052 13.3 0.0 3.6 4 0 0 4 4 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_24 PF13479.6 KXS12907.1 - 0.00013 21.8 0.1 0.28 10.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KXS12907.1 - 0.00014 22.4 0.2 0.47 11.0 0.0 2.8 2 1 0 2 2 2 2 AAA domain AAA_15 PF13175.6 KXS12907.1 - 0.00017 21.4 0.4 0.022 14.5 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 KXS12907.1 - 0.00024 21.1 0.1 1.2 9.1 0.0 3.1 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 KXS12907.1 - 0.0003 20.4 0.3 0.41 10.2 0.0 3.2 3 0 0 3 3 3 1 AAA domain G-alpha PF00503.20 KXS12907.1 - 0.0005 19.3 0.2 0.29 10.3 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit Cytidylate_kin PF02224.18 KXS12907.1 - 0.00052 19.8 0.4 0.49 10.1 0.1 2.4 2 0 0 2 2 2 2 Cytidylate kinase AAA_7 PF12775.7 KXS12907.1 - 0.00073 19.1 0.1 0.67 9.4 0.0 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region Roc PF08477.13 KXS12907.1 - 0.0021 18.3 0.1 1.7 8.9 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase SbcCD_C PF13558.6 KXS12907.1 - 0.0024 18.1 3.5 1.3 9.3 0.4 3.7 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit ATP-synt_ab PF00006.25 KXS12907.1 - 0.0033 17.1 0.1 0.7 9.5 0.0 2.6 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain RNA_helicase PF00910.22 KXS12907.1 - 0.0043 17.4 0.3 3.1 8.2 0.0 3.5 4 0 0 4 4 3 1 RNA helicase AAA_33 PF13671.6 KXS12907.1 - 0.0044 17.2 0.5 1.1 9.5 0.2 3.0 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 KXS12907.1 - 0.0048 16.3 0.0 1.3 8.4 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_30 PF13604.6 KXS12907.1 - 0.0049 16.6 2.9 1.1 8.9 0.1 3.5 2 2 0 2 2 2 1 AAA domain NB-ARC PF00931.22 KXS12907.1 - 0.0056 15.9 0.2 0.45 9.6 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain Sigma54_activat PF00158.26 KXS12907.1 - 0.0063 16.2 0.0 0.55 9.9 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain Gtr1_RagA PF04670.12 KXS12907.1 - 0.0084 15.5 0.1 3.7 6.8 0.0 2.4 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region TniB PF05621.11 KXS12907.1 - 0.011 15.1 0.2 15 5.0 0.0 3.5 4 0 0 4 4 4 0 Bacterial TniB protein AAA_23 PF13476.6 KXS12907.1 - 0.013 16.0 3.4 1.5 9.3 0.0 2.8 3 0 0 3 3 2 0 AAA domain PRK PF00485.18 KXS12907.1 - 0.014 15.2 0.4 4 7.1 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family DUF815 PF05673.13 KXS12907.1 - 0.014 14.5 0.2 4.6 6.3 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 KXS12907.1 - 0.028 14.1 0.0 16 5.1 0.0 3.2 3 0 0 3 3 3 0 IstB-like ATP binding protein MMR_HSR1 PF01926.23 KXS12907.1 - 0.03 14.4 2.6 6.1 7.0 0.0 2.9 3 0 0 3 3 2 0 50S ribosome-binding GTPase DUF87 PF01935.17 KXS12907.1 - 0.04 14.0 3.8 4.9 7.2 0.0 3.7 4 1 0 4 4 3 0 Helicase HerA, central domain NACHT PF05729.12 KXS12907.1 - 0.1 12.5 0.1 5.2 6.9 0.0 2.6 2 0 0 2 2 2 0 NACHT domain TsaE PF02367.17 KXS12907.1 - 0.12 12.4 0.0 6.8 6.7 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 KXS12907.1 - 0.15 12.3 0.1 25 5.1 0.0 2.8 2 0 0 2 2 2 0 AAA domain Ploopntkinase3 PF18751.1 KXS12907.1 - 0.21 11.5 1.4 31 4.4 0.0 3.2 3 1 0 3 3 3 0 P-loop Nucleotide Kinase3 ABC_ATPase PF09818.9 KXS12907.1 - 0.33 9.7 2.7 4.5 5.9 0.2 2.5 3 0 0 3 3 3 0 Predicted ATPase of the ABC class AAA_17 PF13207.6 KXS12907.1 - 1.3 9.5 3.6 12 6.4 0.1 3.4 4 0 0 4 4 2 0 AAA domain Herpes_pp85 PF04637.12 KXS12908.1 - 7.4 4.9 7.1 11 4.3 7.1 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Lactamase_B_2 PF12706.7 KXS12909.1 - 3.9e-35 121.2 0.0 1.4e-34 119.4 0.0 1.8 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KXS12909.1 - 4.2e-14 52.7 0.0 2.8e-13 50.1 0.0 2.0 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KXS12909.1 - 0.011 15.8 0.0 0.1 12.6 0.0 2.4 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily VWA_2 PF13519.6 KXS12910.1 - 0.00024 21.7 0.0 0.0023 18.5 0.0 2.2 2 1 0 2 2 2 1 von Willebrand factor type A domain Zn_clus PF00172.18 KXS12911.1 - 1.5e-08 34.6 7.1 3.1e-08 33.6 7.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXS12911.1 - 3.9e-06 26.1 0.0 5.4e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain ABC_membrane PF00664.23 KXS12912.1 - 8e-104 347.1 22.4 8.9e-57 192.8 3.0 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KXS12912.1 - 1.2e-68 229.9 0.2 2.4e-35 122.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KXS12912.1 - 2.4e-18 66.4 0.2 1.5e-07 31.1 0.0 3.9 2 2 2 4 4 4 2 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.12 KXS12912.1 - 7.5e-10 38.4 0.8 0.002 17.5 0.0 3.2 3 0 0 3 3 3 2 Zeta toxin APS_kinase PF01583.20 KXS12912.1 - 8.8e-08 32.2 1.0 0.00015 21.7 0.1 2.9 3 0 0 3 3 2 2 Adenylylsulphate kinase ABC_ATPase PF09818.9 KXS12912.1 - 1e-06 27.9 1.7 0.004 16.0 0.2 2.6 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_16 PF13191.6 KXS12912.1 - 1.1e-06 29.1 4.0 0.018 15.5 0.2 3.0 2 2 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 KXS12912.1 - 1.7e-06 28.3 2.4 0.13 12.5 0.4 3.8 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KXS12912.1 - 1.9e-06 27.5 0.8 0.015 15.0 0.1 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain G-alpha PF00503.20 KXS12912.1 - 7.4e-06 25.3 0.1 0.025 13.8 0.0 2.5 3 0 0 3 3 3 2 G-protein alpha subunit AAA PF00004.29 KXS12912.1 - 0.0001 22.7 1.0 0.31 11.5 0.2 4.0 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.6 KXS12912.1 - 0.00013 22.1 4.1 0.97 9.7 0.3 4.4 3 2 0 3 3 2 2 Putative exonuclease SbcCD, C subunit RsgA_GTPase PF03193.16 KXS12912.1 - 0.00013 21.9 0.6 0.73 9.7 0.0 2.8 3 0 0 3 3 2 2 RsgA GTPase AAA_15 PF13175.6 KXS12912.1 - 0.00015 21.6 0.0 0.37 10.5 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 KXS12912.1 - 0.00024 21.0 0.3 0.17 11.6 0.1 3.3 2 1 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 KXS12912.1 - 0.00054 20.5 0.0 0.097 13.2 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KXS12912.1 - 0.00065 19.5 7.2 0.4 10.4 0.5 3.9 3 2 0 3 3 2 2 AAA domain AAA_5 PF07728.14 KXS12912.1 - 0.001 19.0 0.1 0.55 10.2 0.0 3.2 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 KXS12912.1 - 0.0011 18.7 0.0 1.1 9.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 KXS12912.1 - 0.0012 19.0 0.0 0.55 10.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain PRK PF00485.18 KXS12912.1 - 0.0024 17.6 0.1 1.4 8.6 0.0 2.3 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_7 PF12775.7 KXS12912.1 - 0.0039 16.7 0.1 0.92 9.0 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region DUF87 PF01935.17 KXS12912.1 - 0.0041 17.3 6.2 0.029 14.5 0.1 2.8 3 0 0 3 3 3 1 Helicase HerA, central domain AAA_28 PF13521.6 KXS12912.1 - 0.0049 17.1 0.4 3.2 8.0 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KXS12912.1 - 0.0089 15.6 3.3 1.4 8.4 0.4 3.4 3 0 0 3 3 3 1 AAA domain IstB_IS21 PF01695.17 KXS12912.1 - 0.011 15.5 1.0 22 4.7 0.0 4.1 4 0 0 4 4 4 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 KXS12912.1 - 0.012 15.0 0.2 4 6.8 0.0 3.3 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI NB-ARC PF00931.22 KXS12912.1 - 0.018 14.3 1.5 1.2 8.2 0.0 2.7 3 0 0 3 3 3 0 NB-ARC domain AAA_17 PF13207.6 KXS12912.1 - 0.024 15.1 0.0 7.8 6.9 0.0 3.1 3 0 0 3 3 2 0 AAA domain DUF815 PF05673.13 KXS12912.1 - 0.035 13.3 0.1 3.7 6.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) RNA_helicase PF00910.22 KXS12912.1 - 0.039 14.3 0.0 14 6.1 0.0 2.5 2 0 0 2 2 2 0 RNA helicase NACHT PF05729.12 KXS12912.1 - 0.047 13.6 0.0 6.1 6.7 0.0 2.6 2 0 0 2 2 2 0 NACHT domain SRP54 PF00448.22 KXS12912.1 - 0.071 12.7 0.1 16 5.0 0.0 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Sigma54_activat PF00158.26 KXS12912.1 - 0.072 12.8 0.0 2 8.1 0.0 2.6 3 0 0 3 3 2 0 Sigma-54 interaction domain MMR_HSR1 PF01926.23 KXS12912.1 - 0.1 12.7 0.1 13 5.9 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase KAP_NTPase PF07693.14 KXS12912.1 - 0.14 11.4 0.0 1.7 7.8 0.0 2.3 2 0 0 2 2 2 0 KAP family P-loop domain AAA_23 PF13476.6 KXS12912.1 - 0.49 10.9 4.3 6.8 7.1 0.1 3.0 3 0 0 3 3 2 0 AAA domain DUF4787 PF16029.5 KXS12913.1 - 0.047 13.8 1.3 0.09 12.9 1.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4787) Ribonuclease_3 PF00636.26 KXS12914.1 - 6.9e-33 113.4 0.0 6.3e-17 62.1 0.0 2.8 2 0 0 2 2 2 2 Ribonuclease III domain Helicase_C PF00271.31 KXS12914.1 - 1.8e-17 63.6 0.2 1.5e-16 60.7 0.2 2.2 1 1 0 1 1 1 1 Helicase conserved C-terminal domain Ribonucleas_3_3 PF14622.6 KXS12914.1 - 2.6e-16 59.9 0.1 2.7e-06 27.5 0.0 3.8 3 1 0 3 3 3 2 Ribonuclease-III-like Dicer_dimer PF03368.14 KXS12914.1 - 4.2e-15 55.7 0.0 1.1e-14 54.4 0.0 1.6 1 0 0 1 1 1 1 Dicer dimerisation domain ResIII PF04851.15 KXS12914.1 - 1.1e-12 48.3 0.1 2.4e-12 47.2 0.1 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KXS12914.1 - 5.6e-12 45.8 0.0 1.1e-11 44.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase PhoH PF02562.16 KXS12914.1 - 0.1 12.0 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Dicty_REP PF05086.12 KXS12916.1 - 0.52 8.2 13.5 0.91 7.4 13.4 1.3 1 1 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Methyltransf_PK PF05891.12 KXS12917.1 - 5.2e-68 228.8 0.0 7.1e-68 228.4 0.0 1.2 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 KXS12917.1 - 1.1e-10 42.0 0.0 2.4e-10 41.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXS12917.1 - 4.1e-09 36.5 0.0 7.8e-09 35.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXS12917.1 - 2.1e-08 34.7 0.0 4.1e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXS12917.1 - 1.4e-06 29.0 0.0 3e-06 27.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Bin3 PF06859.12 KXS12917.1 - 0.022 15.4 0.0 0.035 14.8 0.0 1.4 1 0 0 1 1 1 0 Bicoid-interacting protein 3 (Bin3) Methyltransf_2 PF00891.18 KXS12917.1 - 0.024 13.9 0.1 0.071 12.4 0.1 1.9 1 1 0 1 1 1 0 O-methyltransferase domain adh_short_C2 PF13561.6 KXS12918.1 - 1.1e-26 93.9 0.5 8.5e-25 87.7 0.5 3.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXS12918.1 - 7.8e-25 87.5 0.0 8e-23 80.9 0.0 2.5 1 1 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 KXS12918.1 - 0.013 15.0 0.0 0.024 14.1 0.0 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family KR PF08659.10 KXS12918.1 - 0.077 12.9 0.1 0.2 11.6 0.0 1.7 2 0 0 2 2 2 0 KR domain F-box PF00646.33 KXS12919.1 - 3.8e-07 29.8 2.4 3.8e-07 29.8 2.4 2.1 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KXS12919.1 - 7.3e-07 29.0 1.6 2e-06 27.6 1.6 1.8 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 KXS12919.1 - 0.12 12.3 1.5 0.14 12.0 0.1 1.8 2 0 0 2 2 2 0 F-box TALPID3 PF15324.6 KXS12921.1 - 2.6 5.6 7.6 3.4 5.2 7.6 1.1 1 0 0 1 1 1 0 Hedgehog signalling target NMO PF03060.15 KXS12923.1 - 2.2e-62 211.4 2.5 1.4e-60 205.4 2.5 2.0 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KXS12923.1 - 2.1e-15 56.6 0.1 4.8e-14 52.1 0.1 2.1 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KXS12923.1 - 5.5e-05 22.3 3.5 0.0011 18.0 2.6 2.8 2 1 1 3 3 3 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 KXS12923.1 - 0.0002 20.6 0.6 0.00099 18.3 0.2 2.0 2 0 0 2 2 2 1 Conserved region in glutamate synthase NanE PF04131.14 KXS12923.1 - 0.00082 18.6 0.1 0.00082 18.6 0.1 1.7 2 0 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase TMP-TENI PF02581.17 KXS12923.1 - 0.0039 16.6 0.2 0.0064 15.9 0.2 1.4 1 0 0 1 1 1 1 Thiamine monophosphate synthase Peripla_BP_6 PF13458.6 KXS12923.1 - 0.0078 15.9 0.1 4.8 6.7 0.0 2.5 2 1 0 2 2 2 2 Periplasmic binding protein His_biosynth PF00977.21 KXS12923.1 - 0.012 15.1 0.3 0.038 13.5 0.2 1.8 2 0 0 2 2 2 0 Histidine biosynthesis protein ThiG PF05690.14 KXS12923.1 - 0.032 13.5 0.4 0.088 12.1 0.1 1.8 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG RNA_pol_RpbG PF16992.5 KXS12923.1 - 0.048 13.7 0.1 0.089 12.9 0.1 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase, subunit G Diphthamide_syn PF01866.17 KXS12924.1 - 2e-113 378.8 0.0 6.7e-113 377.1 0.0 1.7 1 1 0 1 1 1 1 Putative diphthamide synthesis protein Methyltransf_16 PF10294.9 KXS12926.1 - 6.1e-06 26.1 0.0 0.00074 19.3 0.0 2.8 1 1 0 1 1 1 1 Lysine methyltransferase BNIP3 PF06553.12 KXS12926.1 - 0.045 13.4 0.5 0.073 12.7 0.1 1.5 2 0 0 2 2 2 0 BNIP3 LRR_8 PF13855.6 KXS12927.1 - 9.7e-22 76.5 7.3 7.4e-08 32.0 4.0 3.8 2 1 2 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 KXS12927.1 - 8.8e-20 70.5 11.2 1.8e-06 28.2 0.8 4.8 2 1 2 6 6 6 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KXS12927.1 - 4e-12 44.9 4.1 0.66 10.7 0.1 7.3 8 0 0 8 8 8 3 Leucine Rich Repeat LRR_6 PF13516.6 KXS12927.1 - 5.2e-05 23.0 13.5 3 8.1 0.0 6.8 7 1 0 7 7 7 2 Leucine Rich repeat LRR_5 PF13306.6 KXS12927.1 - 0.006 16.5 0.2 0.26 11.2 0.0 2.2 1 1 1 2 2 2 1 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KXS12927.1 - 0.011 15.2 2.1 0.082 12.4 1.5 2.4 1 1 2 3 3 3 0 Leucine-rich repeat Ank_2 PF12796.7 KXS12928.1 - 2.2e-19 69.8 0.0 5e-07 30.2 0.0 4.4 3 1 2 5 5 5 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXS12928.1 - 7.9e-17 61.4 0.1 3.7e-07 30.6 0.0 5.5 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXS12928.1 - 2.9e-13 49.8 0.1 4e-05 23.8 0.1 5.4 4 2 1 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXS12928.1 - 6.8e-12 44.5 0.0 0.00071 19.8 0.0 5.9 6 0 0 6 6 6 2 Ankyrin repeat Ank PF00023.30 KXS12928.1 - 5.9e-10 39.1 0.1 0.00086 19.6 0.0 4.7 5 0 0 5 5 5 2 Ankyrin repeat DUF4034 PF13226.6 KXS12929.1 - 0.021 14.2 0.1 0.17 11.2 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4034) Ank_2 PF12796.7 KXS12930.1 - 1.6e-21 76.7 0.1 4.6e-07 30.3 0.1 4.3 3 1 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXS12930.1 - 1.6e-13 49.5 1.0 0.053 14.1 0.0 7.1 7 0 0 7 7 7 3 Ankyrin repeat Ank_4 PF13637.6 KXS12930.1 - 1.8e-13 50.7 0.3 0.0076 16.8 0.0 5.8 6 0 0 6 6 6 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXS12930.1 - 1.2e-12 47.8 1.8 0.0029 17.9 0.2 5.2 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 KXS12930.1 - 1.5e-10 41.0 3.6 0.12 12.9 0.1 6.9 7 0 0 7 7 7 3 Ankyrin repeat Ribul_P_3_epim PF00834.19 KXS12931.1 - 2.7e-71 239.1 0.0 3.1e-71 238.9 0.0 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family ThiG PF05690.14 KXS12931.1 - 0.027 13.8 0.1 0.04 13.2 0.1 1.2 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG OMPdecase PF00215.24 KXS12931.1 - 0.038 13.6 0.0 0.16 11.5 0.0 1.9 2 0 0 2 2 2 0 Orotidine 5'-phosphate decarboxylase / HUMPS family AP_endonuc_2 PF01261.24 KXS12931.1 - 0.13 11.7 0.0 8.1 5.8 0.0 2.3 2 1 0 2 2 2 0 Xylose isomerase-like TIM barrel His_biosynth PF00977.21 KXS12931.1 - 0.14 11.6 0.0 0.4 10.1 0.0 1.8 2 0 0 2 2 2 0 Histidine biosynthesis protein Sulf_transp PF04143.14 KXS12932.1 - 2.3e-31 109.5 31.7 1.2e-29 103.9 31.7 2.1 1 1 0 1 1 1 1 Sulphur transport PetM PF08041.11 KXS12932.1 - 0.46 10.1 7.8 0.045 13.4 1.6 2.7 2 0 0 2 2 2 0 PetM family of cytochrome b6f complex subunit 7 Isy1 PF06246.12 KXS12933.1 - 1e-91 307.1 1.5 1e-91 307.1 1.5 2.1 2 0 0 2 2 2 1 Isy1-like splicing family DUF2201_N PF13203.6 KXS12933.1 - 1.5 8.4 8.8 2.5 7.6 8.8 1.4 1 0 0 1 1 1 0 Putative metallopeptidase domain RR_TM4-6 PF06459.12 KXS12933.1 - 6.4 6.5 11.3 9 6.0 11.3 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 UCH PF00443.29 KXS12934.1 - 4.5e-51 173.8 0.0 6.9e-51 173.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KXS12934.1 - 3.3e-21 76.2 0.0 4.1e-20 72.6 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KXS12934.1 - 0.00023 21.4 6.1 0.00023 21.4 6.1 3.0 2 1 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein Zn-ribbon_8 PF09723.10 KXS12934.1 - 0.97 9.6 13.4 3.7 7.7 0.2 4.2 4 0 0 4 4 4 0 Zinc ribbon domain WD40 PF00400.32 KXS12935.1 - 1.4e-16 60.6 0.0 0.00086 20.1 0.0 6.2 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXS12935.1 - 8.4e-12 45.2 0.0 0.068 13.5 0.0 5.6 2 2 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 KXS12935.1 - 0.0071 15.1 0.0 2.9 6.5 0.0 2.8 2 1 1 3 3 3 2 Nup133 N terminal like Frtz PF11768.8 KXS12935.1 - 0.14 10.5 0.0 11 4.2 0.0 2.5 3 0 0 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz NUP PF06516.11 KXS12935.1 - 0.17 11.1 0.0 0.28 10.3 0.0 1.2 1 0 0 1 1 1 0 Purine nucleoside permease (NUP) Bmt2 PF11968.8 KXS12936.1 - 6.7e-45 153.6 0.0 2.4e-44 151.8 0.0 1.9 1 1 0 1 1 1 1 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 AAA_2 PF07724.14 KXS12937.1 - 9.6e-42 143.0 0.0 1.5e-41 142.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Ank_5 PF13857.6 KXS12937.1 - 1.1e-19 70.2 0.0 1.1e-09 38.4 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KXS12937.1 - 7e-18 64.2 0.1 9.8e-08 32.1 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 KXS12937.1 - 8.1e-17 59.6 0.3 4.1e-07 29.8 0.1 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 KXS12937.1 - 1.9e-16 60.4 0.0 1.2e-07 32.2 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXS12937.1 - 2.5e-13 50.2 0.6 6.5e-05 23.4 0.1 3.2 2 1 1 3 3 3 3 Ankyrin repeats (many copies) AAA_5 PF07728.14 KXS12937.1 - 3.7e-10 39.9 0.0 8.9e-10 38.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ClpB_D2-small PF10431.9 KXS12937.1 - 1.4e-09 37.8 0.0 5.9e-09 35.9 0.0 2.1 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 KXS12937.1 - 2.7e-06 27.8 0.0 5.8e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KXS12937.1 - 1.6e-05 24.7 0.0 2.6e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain Torsin PF06309.11 KXS12937.1 - 0.00026 21.1 0.0 0.00058 20.0 0.0 1.5 1 0 0 1 1 1 1 Torsin AAA_16 PF13191.6 KXS12937.1 - 0.0011 19.4 0.0 0.027 14.9 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.12 KXS12937.1 - 0.0058 15.9 0.8 0.013 14.8 0.0 2.0 3 0 0 3 3 3 1 Zeta toxin AAA_3 PF07726.11 KXS12937.1 - 0.014 15.3 0.0 0.086 12.7 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KXS12937.1 - 0.034 14.4 0.0 0.23 11.7 0.0 2.3 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.22 KXS12937.1 - 0.054 13.1 0.0 0.092 12.4 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain YchF-GTPase_C PF06071.13 KXS12937.1 - 0.066 13.4 0.0 0.19 12.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF933) MobB PF03205.14 KXS12937.1 - 0.083 12.8 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.27 KXS12937.1 - 0.1 13.1 0.0 0.23 11.9 0.0 1.7 1 0 0 1 1 1 0 ABC transporter Mg_chelatase PF01078.21 KXS12937.1 - 0.17 11.2 0.1 3.1 7.1 0.1 2.2 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI Peptidase_C14 PF00656.22 KXS12938.1 - 4.9e-42 144.6 0.0 7.3e-42 144.0 0.0 1.2 1 0 0 1 1 1 1 Caspase domain Glyco_hydro_18 PF00704.28 KXS12939.1 - 1.1e-68 232.3 0.0 1.3e-68 232.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Isochorismatase PF00857.20 KXS12940.1 - 2.4e-28 99.5 0.1 2.9e-28 99.2 0.1 1.1 1 0 0 1 1 1 1 Isochorismatase family Cyclin_N PF00134.23 KXS12941.1 - 1.1e-27 96.3 0.2 2.7e-27 95.0 0.0 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KXS12941.1 - 0.0004 20.4 0.1 0.00094 19.3 0.1 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain ECH_1 PF00378.20 KXS12942.1 - 1.4e-37 129.4 0.0 2e-37 128.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXS12942.1 - 1.9e-23 83.5 0.6 5.8e-20 72.1 0.1 2.1 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase PIG-P PF08510.12 KXS12944.1 - 2.1e-32 111.6 0.0 3.1e-32 111.0 0.0 1.3 1 0 0 1 1 1 1 PIG-P DPM2 PF07297.12 KXS12944.1 - 0.0018 18.5 5.3 0.0032 17.7 5.3 1.3 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) DUF4131 PF13567.6 KXS12944.1 - 0.0077 15.9 0.1 0.011 15.3 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4131) zf-XS PF03470.14 KXS12944.1 - 0.55 10.5 1.3 1.2 9.5 1.3 1.6 1 0 0 1 1 1 0 XS zinc finger domain F-box PF00646.33 KXS12945.1 - 0.0012 18.7 0.0 0.0026 17.6 0.0 1.6 1 0 0 1 1 1 1 F-box domain ADH_zinc_N PF00107.26 KXS12947.1 - 3.1e-08 33.6 1.1 2.2e-05 24.4 0.0 2.9 3 0 0 3 3 3 2 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXS12947.1 - 1.2e-05 26.3 0.0 2.7e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXS12947.1 - 0.00071 19.4 0.0 0.0019 18.1 0.0 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain SET PF00856.28 KXS12948.1 - 2.4e-12 47.6 0.0 4e-12 46.8 0.0 1.5 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.18 KXS12948.1 - 0.0018 18.3 3.1 0.0018 18.3 3.1 2.9 3 2 0 3 3 3 1 MYND finger Myb_DNA-bind_3 PF12776.7 KXS12949.1 - 9.6e-13 48.9 0.8 9.6e-13 48.9 0.8 2.0 2 1 1 3 3 3 1 Myb/SANT-like DNA-binding domain Effector_1 PF04518.12 KXS12949.1 - 0.031 13.4 0.1 0.045 12.9 0.1 1.1 1 0 0 1 1 1 0 Effector from type III secretion system Pirin PF02678.16 KXS12950.1 - 6e-21 74.4 0.3 1.6e-20 73.1 0.2 1.7 2 0 0 2 2 2 1 Pirin Pirin_C PF05726.13 KXS12950.1 - 2.4e-15 56.8 0.0 5.4e-15 55.6 0.0 1.6 1 0 0 1 1 1 1 Pirin C-terminal cupin domain tRNA-synt_1c_C PF03950.18 KXS12950.1 - 0.27 11.1 0.0 0.41 10.5 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), anti-codon binding domain DSBA PF01323.20 KXS12953.1 - 6.4e-51 172.9 0.0 1.6e-26 93.3 0.0 2.5 2 1 0 2 2 2 2 DSBA-like thioredoxin domain Rep_fac_C PF08542.11 KXS12954.1 - 1e-21 77.1 0.0 2e-21 76.2 0.0 1.5 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 KXS12954.1 - 1.6e-12 47.5 0.0 1.1e-08 35.0 0.1 2.3 1 1 1 2 2 2 2 DNA polymerase III, delta subunit AAA PF00004.29 KXS12954.1 - 3.8e-12 46.8 0.0 6.6e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 KXS12954.1 - 3.4e-07 30.4 0.0 5.1e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 KXS12954.1 - 9.3e-07 28.9 0.0 1.5e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain RuvB_N PF05496.12 KXS12954.1 - 1.9e-06 27.7 0.1 5.8e-06 26.1 0.1 1.9 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KXS12954.1 - 2.2e-06 28.0 0.2 0.03 14.6 0.0 2.6 2 1 1 3 3 2 2 AAA domain AAA_16 PF13191.6 KXS12954.1 - 3.5e-06 27.5 0.0 0.00044 20.7 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain Viral_helicase1 PF01443.18 KXS12954.1 - 4.6e-05 23.3 0.1 0.00021 21.1 0.0 1.9 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_3 PF07726.11 KXS12954.1 - 0.00012 22.0 0.0 0.00023 21.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 KXS12954.1 - 0.00033 20.1 0.1 0.0079 15.6 0.1 2.2 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_11 PF13086.6 KXS12954.1 - 0.002 18.0 0.0 0.0028 17.5 0.0 1.4 1 1 0 1 1 1 1 AAA domain TniB PF05621.11 KXS12954.1 - 0.0043 16.5 0.1 0.31 10.4 0.0 2.4 1 1 1 2 2 2 1 Bacterial TniB protein AAA_19 PF13245.6 KXS12954.1 - 0.0045 17.3 0.3 0.11 12.8 0.2 2.2 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 KXS12954.1 - 0.0055 16.7 0.0 0.013 15.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 KXS12954.1 - 0.007 16.1 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain DNA_pol3_delta PF06144.13 KXS12954.1 - 0.009 15.8 0.1 0.015 15.1 0.1 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit NTPase_1 PF03266.15 KXS12954.1 - 0.014 15.3 0.1 0.049 13.6 0.1 1.9 1 1 0 1 1 1 0 NTPase AAA_assoc_2 PF16193.5 KXS12954.1 - 0.022 15.1 0.0 0.067 13.5 0.0 1.8 2 0 0 2 2 1 0 AAA C-terminal domain ABC_tran PF00005.27 KXS12954.1 - 0.022 15.2 0.0 0.055 14.0 0.0 1.6 1 1 0 1 1 1 0 ABC transporter DEAD PF00270.29 KXS12954.1 - 0.031 14.0 0.1 0.93 9.2 0.0 2.3 1 1 1 2 2 2 0 DEAD/DEAH box helicase AAA_28 PF13521.6 KXS12954.1 - 0.032 14.5 0.0 0.052 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KXS12954.1 - 0.04 14.5 0.2 0.28 11.7 0.0 2.4 3 0 0 3 3 3 0 AAA domain MeaB PF03308.16 KXS12954.1 - 0.074 12.0 0.0 0.23 10.4 0.0 1.8 1 1 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ATPase_2 PF01637.18 KXS12954.1 - 0.084 12.8 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea RhodobacterPufX PF11511.8 KXS12954.1 - 0.12 12.0 0.3 0.24 11.0 0.3 1.4 1 0 0 1 1 1 0 Intrinsic membrane protein PufX AAA_25 PF13481.6 KXS12954.1 - 0.12 12.0 0.0 0.4 10.2 0.0 2.0 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KXS12954.1 - 0.12 12.7 0.0 0.28 11.6 0.0 1.7 1 1 0 1 1 1 0 RNA helicase SgrR_N PF12793.7 KXS12954.1 - 0.16 12.2 0.1 0.38 11.0 0.1 1.6 1 0 0 1 1 1 0 Sugar transport-related sRNA regulator N-term AAA_30 PF13604.6 KXS12954.1 - 0.18 11.5 0.0 0.46 10.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain Kelch_1 PF01344.25 KXS12955.1 - 9.4e-10 37.9 9.1 0.00011 21.6 0.3 4.7 5 0 0 5 5 5 3 Kelch motif Kelch_6 PF13964.6 KXS12955.1 - 2e-08 34.2 10.9 0.038 14.3 0.2 5.2 4 1 1 5 5 5 3 Kelch motif Kelch_3 PF13415.6 KXS12955.1 - 1.5e-05 25.2 6.7 3.8 7.9 0.0 5.8 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_5 PF13854.6 KXS12955.1 - 0.00015 21.7 10.7 0.3 11.1 0.1 4.8 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.15 KXS12955.1 - 0.0011 18.9 7.2 8.7 6.5 0.1 5.0 5 0 0 5 5 5 3 Kelch motif Kelch_4 PF13418.6 KXS12955.1 - 0.003 17.5 10.0 3.3 7.8 0.2 5.3 5 0 0 5 5 5 2 Galactose oxidase, central domain Abhydrolase_6 PF12697.7 KXS12956.1 - 4.5e-06 27.4 0.4 8.9e-06 26.5 0.1 1.5 1 1 1 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KXS12956.1 - 0.00017 21.2 0.0 0.081 12.4 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KXS12956.1 - 0.00085 19.0 0.0 0.0016 18.1 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 KXS12956.1 - 0.0027 17.6 0.0 0.0068 16.3 0.0 1.7 2 1 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXS12956.1 - 0.059 12.6 0.0 0.12 11.6 0.0 1.5 1 1 0 1 1 1 0 Serine aminopeptidase, S33 R3H PF01424.22 KXS12957.1 - 5.1e-15 55.2 0.1 9.8e-15 54.3 0.1 1.5 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.17 KXS12957.1 - 1.7e-05 24.7 61.2 0.00033 20.7 16.6 14.2 14 1 0 14 14 14 7 NF-X1 type zinc finger 3Beta_HSD PF01073.19 KXS12958.1 - 5.8e-50 169.9 0.1 1.3e-49 168.7 0.1 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KXS12958.1 - 6.8e-10 38.8 0.1 1.6e-09 37.6 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXS12958.1 - 9.3e-06 25.3 0.1 0.00021 20.8 0.2 2.5 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KXS12958.1 - 1.3e-05 24.5 0.0 3.2e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.17 KXS12958.1 - 3.2e-05 23.2 0.1 8.4e-05 21.8 0.0 1.6 2 0 0 2 2 2 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KXS12958.1 - 0.044 12.9 0.1 0.093 11.8 0.1 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein COX7a PF02238.15 KXS12958.1 - 0.077 13.4 0.1 0.19 12.1 0.1 1.6 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VII NAD_binding_10 PF13460.6 KXS12958.1 - 0.13 12.1 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding Xan_ur_permease PF00860.20 KXS12959.1 - 9.9e-64 215.4 29.7 3.2e-62 210.5 29.7 2.1 1 1 0 1 1 1 1 Permease family Transmemb_17 PF09799.9 KXS12959.1 - 8.5 7.0 9.6 0.87 10.2 2.8 2.6 2 0 0 2 2 2 0 Predicted membrane protein Transferase PF02458.15 KXS12960.1 - 4.8e-07 28.8 0.0 0.0078 14.9 0.0 2.1 2 0 0 2 2 2 2 Transferase family SpoIIE PF07228.12 KXS12961.1 - 3.4e-08 33.6 0.0 4.7e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 KXS12961.1 - 0.011 15.3 0.6 0.088 12.4 0.6 2.2 1 1 0 1 1 1 0 Protein phosphatase 2C PP2C PF00481.21 KXS12961.1 - 0.012 15.2 0.3 0.99 9.0 0.1 2.1 2 0 0 2 2 2 0 Protein phosphatase 2C Chitin_bind_1 PF00187.19 KXS12965.1 - 5.6e-28 97.1 102.4 1.2e-10 41.7 24.3 4.9 5 0 0 5 5 5 3 Chitin recognition protein DPBB_1 PF03330.18 KXS12965.1 - 0.00022 21.4 0.2 0.00022 21.4 0.2 2.7 3 1 0 3 3 3 1 Lytic transglycolase CAP_N PF01213.19 KXS12965.1 - 4.4 6.7 5.6 7.4 6.0 0.8 2.1 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal zf-MIZ PF02891.20 KXS12966.1 - 1.1e-10 41.1 1.1 2e-10 40.3 1.1 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 KXS12966.1 - 2.5e-05 24.0 0.1 4.7e-05 23.1 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit F-box-like PF12937.7 KXS12967.1 - 0.0018 18.1 0.1 0.0018 18.1 0.1 2.8 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 KXS12967.1 - 0.0031 17.3 0.0 0.0031 17.3 0.0 3.1 4 0 0 4 4 4 1 F-box domain AhpC-TSA PF00578.21 KXS12968.1 - 2.4e-31 108.2 0.0 3.3e-31 107.8 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.9 KXS12968.1 - 6.6e-12 45.1 0.6 1.3e-11 44.2 0.6 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.10 KXS12968.1 - 1.9e-11 43.9 0.0 2.4e-11 43.6 0.0 1.1 1 0 0 1 1 1 1 Redoxin PS_Dcarbxylase PF02666.15 KXS12968.1 - 0.044 13.3 0.0 0.068 12.7 0.0 1.3 1 0 0 1 1 1 0 Phosphatidylserine decarboxylase AhpC-TSA_2 PF13911.6 KXS12968.1 - 0.06 13.5 0.0 0.076 13.1 0.0 1.3 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme ASH PF15780.5 KXS12968.1 - 0.13 12.4 0.0 0.26 11.5 0.0 1.4 1 0 0 1 1 1 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Beta-lactamase PF00144.24 KXS12969.1 - 9.3e-33 113.9 0.5 3e-32 112.2 0.5 1.8 1 1 0 1 1 1 1 Beta-lactamase Hydrolase_4 PF12146.8 KXS12970.1 - 5.5e-14 52.0 0.0 5.8e-13 48.6 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KXS12970.1 - 2.8e-10 40.3 0.0 2.8e-09 37.0 0.0 2.0 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXS12970.1 - 7.8e-07 29.9 0.0 5.6e-06 27.1 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family LIP PF03583.14 KXS12970.1 - 0.0089 15.4 0.0 0.019 14.3 0.0 1.5 2 0 0 2 2 2 1 Secretory lipase DUF915 PF06028.11 KXS12970.1 - 0.043 13.1 0.0 0.41 9.9 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Ser_hydrolase PF06821.13 KXS12970.1 - 0.058 13.3 0.0 3.1 7.6 0.0 2.3 2 0 0 2 2 2 0 Serine hydrolase DUF2017 PF09438.10 KXS12970.1 - 0.092 12.6 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF2017) DUF900 PF05990.12 KXS12970.1 - 0.21 11.1 0.2 0.4 10.1 0.2 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) SpoIIE PF07228.12 KXS12971.1 - 0.022 14.7 0.1 0.042 13.7 0.1 1.6 1 1 0 1 1 1 0 Stage II sporulation protein E (SpoIIE) ABC_membrane PF00664.23 KXS12972.1 - 5.4e-117 390.3 21.4 7.5e-63 212.7 5.4 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KXS12972.1 - 3.5e-56 189.5 0.0 2.8e-33 115.3 0.0 3.1 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KXS12972.1 - 9.3e-18 64.5 0.0 7.2e-07 28.9 0.0 3.2 2 1 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KXS12972.1 - 0.00018 22.0 1.1 0.0041 17.5 0.4 3.2 2 1 0 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.12 KXS12972.1 - 0.00026 20.3 1.0 0.0014 17.9 0.0 2.5 3 0 0 3 3 3 1 Zeta toxin SbcCD_C PF13558.6 KXS12972.1 - 0.0049 17.1 4.1 1 9.6 0.5 3.8 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 KXS12972.1 - 0.0065 16.2 0.1 0.017 14.8 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA PF00004.29 KXS12972.1 - 0.008 16.6 0.6 1.1 9.7 0.4 3.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 KXS12972.1 - 0.008 15.9 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 KXS12972.1 - 0.013 15.5 0.0 0.036 14.0 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase G-alpha PF00503.20 KXS12972.1 - 0.013 14.6 0.0 0.023 13.9 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit ABC_ATPase PF09818.9 KXS12972.1 - 0.024 13.4 1.6 2.8 6.6 0.1 2.6 3 0 0 3 3 3 0 Predicted ATPase of the ABC class AAA_22 PF13401.6 KXS12972.1 - 0.036 14.3 0.1 0.48 10.7 0.1 2.8 2 1 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KXS12972.1 - 0.045 13.3 0.0 0.09 12.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_21 PF13304.6 KXS12972.1 - 0.054 13.3 0.1 0.28 11.0 0.0 2.2 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 KXS12972.1 - 0.057 13.1 1.7 0.41 10.3 0.0 3.0 4 0 0 4 4 3 0 AAA domain AAA_24 PF13479.6 KXS12972.1 - 0.1 12.3 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.20 KXS12972.1 - 0.11 12.3 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase Auto_anti-p27 PF06677.12 KXS12973.1 - 3.5e-25 87.9 9.0 4.6e-13 49.1 1.3 2.2 2 0 0 2 2 2 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Zn_Tnp_IS91 PF14319.6 KXS12973.1 - 0.3 11.1 2.1 1 9.5 0.2 2.1 2 0 0 2 2 2 0 Transposase zinc-binding domain SfsA PF03749.13 KXS12974.1 - 5e-10 39.4 0.0 1.4e-05 25.0 0.0 2.3 2 0 0 2 2 2 2 Sugar fermentation stimulation protein RE domain SfsA_N PF17746.1 KXS12974.1 - 0.00043 20.4 1.1 0.43 10.8 0.0 3.2 3 0 0 3 3 3 2 SfsA N-terminal OB domain Taeniidae_ag PF05596.11 KXS12974.1 - 0.41 10.7 2.5 0.78 9.8 2.5 1.4 1 0 0 1 1 1 0 Taeniidae antigen Ank_3 PF13606.6 KXS12975.1 - 0.011 16.1 0.0 1.6 9.5 0.0 2.8 3 0 0 3 3 3 0 Ankyrin repeat Sec2p PF06428.11 KXS12975.1 - 0.012 15.6 0.2 0.025 14.6 0.2 1.5 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p DUF4140 PF13600.6 KXS12975.1 - 0.02 15.3 0.5 0.049 14.1 0.5 1.6 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Rootletin PF15035.6 KXS12975.1 - 0.076 13.0 0.5 0.12 12.4 0.5 1.2 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion SNase PF00565.17 KXS12976.1 - 4.7e-23 81.7 0.0 6.7e-23 81.2 0.0 1.2 1 0 0 1 1 1 1 Staphylococcal nuclease homologue Polysacc_deac_1 PF01522.21 KXS12978.1 - 9.5e-27 93.4 0.0 1.4e-26 92.8 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.19 KXS12978.1 - 2.6e-16 59.8 45.2 2.3e-09 37.5 17.3 2.6 2 0 0 2 2 2 2 Chitin recognition protein DUF2334 PF10096.9 KXS12978.1 - 0.084 12.5 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) Chitin_bind_1 PF00187.19 KXS12979.1 - 1.1e-28 99.4 75.8 8e-11 42.2 19.7 3.7 3 0 0 3 3 3 3 Chitin recognition protein Polysacc_deac_1 PF01522.21 KXS12979.1 - 6.7e-24 84.2 0.0 9.7e-24 83.6 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 KXS12979.1 - 0.027 14.1 0.0 0.04 13.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) HSP70 PF00012.20 KXS12980.1 - 2.7e-61 207.5 0.0 3.4e-61 207.2 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KXS12980.1 - 1.7e-09 37.0 0.0 1.3e-08 34.1 0.0 2.3 2 1 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 KXS12980.1 - 0.0048 17.3 0.1 0.047 14.1 0.0 2.5 2 0 0 2 2 2 1 Cell division protein FtsA DUF4174 PF13778.6 KXS12980.1 - 0.1 13.1 0.7 0.59 10.6 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4174) FDX-ACB PF03147.14 KXS12980.1 - 0.1 13.0 0.1 0.32 11.4 0.1 1.8 1 0 0 1 1 1 0 Ferredoxin-fold anticodon binding domain HSP70 PF00012.20 KXS12981.1 - 1.8e-18 66.1 0.1 2.4e-18 65.7 0.1 1.0 1 0 0 1 1 1 1 Hsp70 protein DUF3219 PF11514.8 KXS12981.1 - 0.13 12.2 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3219) Chitin_synth_1 PF01644.17 KXS12982.1 - 2.6e-58 196.6 0.0 4.2e-58 195.9 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.15 KXS12982.1 - 2.5e-21 75.9 0.4 4.6e-16 58.5 0.0 2.7 2 1 1 3 3 3 2 Chitin synthase Chitin_synth_1N PF08407.11 KXS12982.1 - 2.1e-17 62.8 0.0 4.8e-17 61.7 0.0 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Glyco_trans_2_3 PF13632.6 KXS12982.1 - 5.2e-12 46.1 0.2 5.2e-12 46.1 0.2 2.7 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KXS12982.1 - 0.054 13.4 0.0 0.088 12.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase like family 2 BORA_N PF15280.6 KXS12982.1 - 0.12 12.0 0.1 0.23 11.1 0.1 1.3 1 0 0 1 1 1 0 Protein aurora borealis N-terminus LcrG PF07216.12 KXS12983.1 - 0.022 14.6 1.4 0.037 14.0 0.2 1.8 1 1 1 2 2 2 0 LcrG protein WbqC PF08889.11 KXS12983.1 - 0.13 12.2 1.8 0.18 11.7 1.8 1.2 1 0 0 1 1 1 0 WbqC-like protein family Pkinase_Tyr PF07714.17 KXS12984.1 - 1.8e-11 43.9 0.0 1.2e-06 28.0 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXS12984.1 - 2.1e-07 30.6 0.0 9.6e-05 21.9 0.0 2.4 2 1 0 2 2 2 2 Protein kinase domain Pkinase PF00069.25 KXS12985.1 - 1.9e-09 37.3 0.0 1.8e-06 27.5 0.0 2.8 3 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXS12985.1 - 0.21 10.8 0.0 3 7.1 0.0 2.1 2 0 0 2 2 2 0 Protein tyrosine kinase BRE1 PF08647.11 KXS12986.1 - 1.5e-05 25.0 10.2 0.0004 20.4 1.4 6.1 2 2 3 6 6 6 2 BRE1 E3 ubiquitin ligase GRAB PF10375.9 KXS12986.1 - 1.9e-05 24.3 3.1 3.8e-05 23.4 3.1 1.5 1 0 0 1 1 1 1 GRIP-related Arf-binding domain Filament PF00038.21 KXS12986.1 - 6.9e-05 22.6 15.9 6.9e-05 22.6 15.9 4.5 2 2 2 4 4 4 2 Intermediate filament protein Spc7 PF08317.11 KXS12986.1 - 0.0014 17.6 10.6 0.0014 17.6 10.6 4.9 2 2 3 5 5 5 2 Spc7 kinetochore protein Atg14 PF10186.9 KXS12986.1 - 0.0044 16.1 6.8 0.0044 16.1 6.8 4.3 2 2 2 4 4 4 1 Vacuolar sorting 38 and autophagy-related subunit 14 DUF5105 PF17118.5 KXS12986.1 - 0.0093 15.8 1.3 0.0093 15.8 1.3 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF5105) DUF1664 PF07889.12 KXS12986.1 - 0.16 12.0 48.1 1.1 9.3 2.0 7.3 3 2 5 8 8 8 0 Protein of unknown function (DUF1664) YqjK PF13997.6 KXS12986.1 - 0.24 11.7 1.9 9.6 6.5 0.2 3.9 3 0 0 3 3 3 0 YqjK-like protein HisK_N PF09385.10 KXS12986.1 - 0.66 9.9 3.6 0.72 9.8 0.6 2.4 2 0 0 2 2 2 0 Histidine kinase N terminal Golgin_A5 PF09787.9 KXS12986.1 - 0.84 9.0 74.6 0.66 9.4 13.6 5.1 2 2 3 5 5 5 0 Golgin subfamily A member 5 DUF948 PF06103.11 KXS12986.1 - 0.95 9.8 26.1 0.036 14.3 2.5 6.1 5 1 0 6 6 6 0 Bacterial protein of unknown function (DUF948) Flg_hook PF02120.16 KXS12986.1 - 2.6 8.0 16.7 5.5 6.9 0.1 4.8 4 1 1 5 5 5 0 Flagellar hook-length control protein FliK DUF2353 PF09789.9 KXS12986.1 - 5.1 6.4 47.9 0.086 12.2 12.7 4.0 2 1 1 4 4 4 0 Uncharacterized coiled-coil protein (DUF2353) NIBRIN_BRCT_II PF16508.5 KXS12986.1 - 6.9 7.0 7.7 2.2 8.6 3.1 2.6 3 0 0 3 3 3 0 Second BRCT domain on Nijmegen syndrome breakage protein Fez1 PF06818.15 KXS12986.1 - 7.7 6.9 71.6 0.062 13.8 12.2 5.2 2 2 3 5 5 5 0 Fez1 CENP-F_leu_zip PF10473.9 KXS12986.1 - 8.9 6.3 74.3 0.23 11.5 5.4 6.2 3 2 4 7 7 6 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AA_permease_2 PF13520.6 KXS12988.1 - 5.6e-07 28.7 13.2 1.8e-05 23.8 5.7 2.2 2 0 0 2 2 2 2 Amino acid permease AA_permease PF00324.21 KXS12988.1 - 6.3e-05 21.8 4.0 0.00012 20.9 4.0 1.4 1 0 0 1 1 1 1 Amino acid permease DUF5418 PF17439.2 KXS12988.1 - 0.5 10.4 6.7 0.81 9.8 6.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5418) Pkinase PF00069.25 KXS12990.1 - 1e-62 211.9 0.0 1.5e-62 211.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS12990.1 - 1.3e-36 126.3 0.0 2e-36 125.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.22 KXS12990.1 - 9.1e-21 73.5 17.8 1.1e-10 41.3 10.2 2.3 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) HR1 PF02185.16 KXS12990.1 - 8.9e-11 41.7 17.1 1.2e-06 28.6 0.5 3.8 4 0 0 4 4 4 2 Hr1 repeat Pkinase_C PF00433.24 KXS12990.1 - 1.1e-10 42.0 3.4 7e-10 39.5 3.4 2.5 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 KXS12990.1 - 0.00016 21.1 0.1 0.00054 19.4 0.0 1.9 2 0 0 2 2 2 1 Kinase-like C1_2 PF03107.16 KXS12990.1 - 0.0066 16.7 14.5 0.024 14.9 7.1 2.4 2 0 0 2 2 2 2 C1 domain Pkinase_fungal PF17667.1 KXS12990.1 - 0.035 12.9 0.0 0.035 12.9 0.0 2.8 2 1 0 2 2 2 0 Fungal protein kinase XAF1_C PF18608.1 KXS12990.1 - 2.7 7.6 5.1 1.2 8.7 1.1 2.5 2 1 1 3 3 3 0 XIAP-associated factor 1 C-terminal domain Phi_1 PF04674.12 KXS12991.1 - 0.089 12.1 0.9 0.17 11.2 0.9 1.5 1 1 0 1 1 1 0 Phosphate-induced protein 1 conserved region Rib PF08428.10 KXS12991.1 - 0.15 12.0 4.2 2.4 8.2 3.9 2.2 2 0 0 2 2 2 0 Rib/alpha-like repeat PH_9 PF15410.6 KXS12992.1 - 1.7e-08 34.9 0.0 2.6e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 KXS12992.1 - 8.9e-06 26.2 0.0 1.5e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 PH domain Cu-oxidase_2 PF07731.14 KXS12993.1 - 1.4e-32 112.3 0.6 2.8e-32 111.3 0.6 1.4 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase PF00394.22 KXS12993.1 - 3.7e-19 69.4 1.7 5.2e-19 68.9 0.7 1.7 2 0 0 2 2 2 1 Multicopper oxidase Rhodanese PF00581.20 KXS12994.1 - 4.9e-11 43.1 0.0 8.2e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain DNA_binding_1 PF01035.20 KXS12995.1 - 5.9e-27 93.6 0.0 8.9e-27 93.0 0.0 1.3 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Methyltransf_1N PF02870.15 KXS12995.1 - 0.018 15.8 0.0 0.034 15.0 0.0 1.5 1 0 0 1 1 1 0 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain HTH_32 PF13565.6 KXS12996.1 - 0.042 14.5 0.1 0.071 13.7 0.1 1.4 1 0 0 1 1 1 0 Homeodomain-like domain zf-MYND PF01753.18 KXS12997.1 - 1.9e-09 37.5 13.2 1.9e-09 37.5 13.2 1.9 2 1 0 2 2 2 1 MYND finger DUF4722 PF15849.5 KXS12997.1 - 0.016 14.9 0.0 0.024 14.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4722) zf-C6H2 PF15801.5 KXS12997.1 - 0.99 9.8 11.8 4 7.8 11.8 2.1 1 1 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Asp PF00026.23 KXS12998.1 - 4.1e-21 75.7 0.0 4.8e-21 75.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease AGTRAP PF06396.11 KXS12999.1 - 0.025 14.4 0.4 0.039 13.8 0.4 1.4 1 1 0 1 1 1 0 Angiotensin II, type I receptor-associated protein (AGTRAP) MMS1_N PF10433.9 KXS13000.1 - 1.8e-94 317.2 0.0 2.4e-94 316.7 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 KXS13000.1 - 7.2e-67 226.0 0.0 1.3e-66 225.2 0.0 1.4 1 0 0 1 1 1 1 CPSF A subunit region Imm45 PF15572.6 KXS13000.1 - 0.12 12.8 0.0 0.28 11.6 0.0 1.6 1 0 0 1 1 1 0 Immunity protein 45 ANAPC10 PF03256.16 KXS13001.1 - 2.8e-51 173.8 0.0 3e-51 173.7 0.0 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) HATPase_c PF02518.26 KXS13002.1 - 4.4e-20 72.3 0.0 1.2e-19 70.9 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KXS13002.1 - 3.2e-14 53.1 0.0 7.8e-14 51.8 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 KXS13002.1 - 3e-12 46.4 0.3 5.6e-12 45.5 0.3 1.5 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain NUDIX PF00293.28 KXS13003.1 - 1.1e-18 67.5 0.8 1.4e-18 67.2 0.8 1.1 1 0 0 1 1 1 1 NUDIX domain Geminin PF07412.12 KXS13006.1 - 0.006 16.4 0.3 0.012 15.3 0.3 1.5 1 0 0 1 1 1 1 Geminin TolA_bind_tri PF16331.5 KXS13006.1 - 0.0069 16.4 3.9 0.01 15.9 0.2 2.7 2 1 0 2 2 2 1 TolA binding protein trimerisation Herpes_BLRF2 PF05812.12 KXS13006.1 - 0.023 14.8 0.4 0.087 13.0 0.4 2.1 1 1 0 1 1 1 0 Herpesvirus BLRF2 protein XLF PF09302.11 KXS13006.1 - 0.056 13.6 0.1 0.43 10.7 0.1 2.1 2 0 0 2 2 2 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component TSC22 PF01166.18 KXS13006.1 - 0.13 12.6 1.2 0.27 11.6 1.2 1.5 1 0 0 1 1 1 0 TSC-22/dip/bun family FAS_I_H PF18314.1 KXS13006.1 - 0.14 11.8 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 Fatty acid synthase type I helical domain ZapB PF06005.12 KXS13006.1 - 0.21 12.1 2.3 0.36 11.3 0.7 2.0 2 0 0 2 2 2 0 Cell division protein ZapB Vps52 PF04129.12 KXS13007.1 - 2.1e-128 429.3 0.0 2.7e-128 428.9 0.0 1.1 1 0 0 1 1 1 1 Vps52 / Sac2 family Sec3_C PF09763.9 KXS13007.1 - 2.1e-10 39.7 3.9 1.9e-09 36.5 3.3 2.0 2 0 0 2 2 2 1 Exocyst complex component Sec3 COG6 PF06419.11 KXS13007.1 - 0.00061 18.1 4.2 0.023 13.0 0.0 2.5 3 0 0 3 3 3 2 Conserved oligomeric complex COG6 COG2 PF06148.11 KXS13007.1 - 0.0013 18.8 1.5 0.0053 16.9 1.5 2.1 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Sec8_exocyst PF04048.14 KXS13007.1 - 0.0044 16.9 0.4 0.011 15.6 0.4 1.6 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain Nup54 PF13874.6 KXS13007.1 - 0.04 14.0 1.0 0.12 12.5 1.0 1.8 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 DUF4315 PF14193.6 KXS13007.1 - 0.26 11.3 1.1 0.58 10.2 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4315) DHR10 PF18595.1 KXS13007.1 - 2.4 8.2 5.7 0.47 10.5 1.4 2.0 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain Cofilin_ADF PF00241.20 KXS13008.1 - 3.1e-36 123.8 1.8 3.4e-36 123.7 1.8 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Pox_MCEL PF03291.16 KXS13009.1 - 1.7e-05 24.1 0.0 1.9e-05 23.9 0.0 1.0 1 0 0 1 1 1 1 mRNA capping enzyme Porin_3 PF01459.22 KXS13011.1 - 6.8e-70 235.6 1.2 7.6e-70 235.5 1.2 1.0 1 0 0 1 1 1 1 Eukaryotic porin DUF756 PF05506.12 KXS13011.1 - 0.11 13.4 0.8 4.5 8.3 0.7 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF756) zf_CCCH_4 PF18345.1 KXS13013.1 - 0.31 11.1 2.9 16 5.7 0.8 2.6 1 1 1 2 2 2 0 Zinc finger domain IIGP PF05049.13 KXS13014.1 - 1.1e-22 80.7 0.0 1.4e-22 80.3 0.0 1.1 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) RsgA_GTPase PF03193.16 KXS13014.1 - 2.8e-07 30.6 0.0 8.2e-06 25.8 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 KXS13014.1 - 1.6e-06 28.1 0.0 2.3e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.18 KXS13014.1 - 0.0039 16.5 0.0 0.0065 15.8 0.0 1.3 1 0 0 1 1 1 1 Septin Dynamin_N PF00350.23 KXS13014.1 - 0.0061 16.6 0.1 0.016 15.3 0.1 1.7 1 1 1 2 2 2 1 Dynamin family AAA_22 PF13401.6 KXS13014.1 - 0.0079 16.5 0.0 0.016 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain Roc PF08477.13 KXS13014.1 - 0.0088 16.3 0.0 0.013 15.7 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase FeoB_N PF02421.18 KXS13014.1 - 0.01 15.4 0.0 0.016 14.7 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_29 PF13555.6 KXS13014.1 - 0.011 15.5 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AIG1 PF04548.16 KXS13014.1 - 0.016 14.5 0.0 0.033 13.5 0.0 1.5 1 0 0 1 1 1 0 AIG1 family ABC_tran PF00005.27 KXS13014.1 - 0.019 15.5 0.0 0.039 14.5 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_16 PF13191.6 KXS13014.1 - 0.025 15.0 0.0 0.038 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain ATP_bind_1 PF03029.17 KXS13014.1 - 0.11 12.3 0.1 0.66 9.7 0.0 2.2 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein FtsK_SpoIIIE PF01580.18 KXS13014.1 - 0.12 11.7 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Ras PF00071.22 KXS13014.1 - 0.14 11.8 0.1 0.29 10.7 0.1 1.7 1 1 0 1 1 1 0 Ras family T2SSE PF00437.20 KXS13014.1 - 0.14 11.2 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_7 PF12775.7 KXS13014.1 - 0.16 11.5 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 KXS13014.1 - 0.19 12.1 0.0 0.45 10.9 0.0 1.7 1 1 0 1 1 1 0 RNA helicase CAF1 PF04857.20 KXS13016.1 - 2.2e-25 89.5 0.2 1.7e-24 86.6 0.2 1.9 1 1 0 1 1 1 1 CAF1 family ribonuclease PhoLip_ATPase_C PF16212.5 KXS13017.1 - 2.6e-26 92.9 5.2 3.7e-26 92.4 5.2 1.1 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal Hydrolase_3 PF08282.12 KXS13017.1 - 0.0039 17.0 0.1 0.0062 16.3 0.1 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KXS13017.1 - 0.064 13.5 0.0 0.093 13.0 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF1186 PF06685.11 KXS13020.1 - 0.27 10.6 0.0 0.39 10.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1186) MFS_1 PF07690.16 KXS13021.1 - 2.7e-32 112.1 36.4 2.7e-32 112.1 36.4 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily SBF_like PF13593.6 KXS13022.1 - 2.5e-83 280.0 17.7 2.9e-83 279.8 17.7 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) SBF PF01758.16 KXS13022.1 - 7.4e-13 48.6 9.0 7.4e-13 48.6 9.0 2.0 1 1 1 2 2 2 1 Sodium Bile acid symporter family CLPTM1 PF05602.12 KXS13023.1 - 1.6e-135 452.5 6.0 1.8e-135 452.3 6.0 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.14 KXS13023.1 - 0.00039 20.1 0.8 0.063 13.1 0.2 2.5 2 0 0 2 2 2 2 PQ loop repeat DUF1097 PF06496.11 KXS13023.1 - 0.055 13.6 0.6 0.13 12.4 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1097) DRMBL PF07522.14 KXS13024.1 - 3.7e-20 72.2 0.0 6.2e-20 71.4 0.0 1.4 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 KXS13024.1 - 4.7e-05 23.0 0.1 0.00022 20.8 0.1 2.1 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KXS13024.1 - 0.3 11.1 5.5 0.48 10.4 3.9 2.0 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily Trehalase PF01204.18 KXS13025.1 - 8.5e-112 374.6 0.1 1.2e-73 248.7 3.4 2.9 2 1 0 2 2 2 2 Trehalase zf-MYND PF01753.18 KXS13027.1 - 6.8e-07 29.3 0.0 2.4e-06 27.5 0.0 2.1 1 1 0 1 1 1 1 MYND finger Sel1 PF08238.12 KXS13027.1 - 8e-05 23.2 15.3 0.25 12.1 0.1 5.7 6 0 0 6 6 6 2 Sel1 repeat AdoMet_MTase PF07757.13 KXS13029.1 - 0.17 12.2 0.0 0.33 11.3 0.0 1.5 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase WD40 PF00400.32 KXS13031.1 - 2.5e-51 170.5 19.5 1.5e-11 44.6 0.2 8.6 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXS13031.1 - 1e-21 77.0 1.0 8.8e-06 25.9 0.0 5.7 3 2 3 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KXS13031.1 - 2.9e-06 27.3 0.7 0.1 12.5 0.0 3.6 2 2 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KXS13031.1 - 0.0016 17.5 0.1 4 6.3 0.0 3.3 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 KXS13031.1 - 0.0032 16.8 0.1 3.2 7.0 0.0 2.8 2 1 1 3 3 3 2 Neuroblastoma-amplified sequence, N terminal LisH PF08513.11 KXS13031.1 - 0.0059 16.5 0.2 0.0096 15.9 0.2 1.3 1 0 0 1 1 1 1 LisH PD40 PF07676.12 KXS13031.1 - 0.03 14.2 0.2 4.1 7.4 0.0 3.7 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat GFA PF04828.14 KXS13032.1 - 1.4e-10 41.3 0.6 2e-10 40.9 0.6 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Haem_bd PF14376.6 KXS13032.1 - 0.061 13.3 1.9 0.43 10.5 0.0 2.1 1 1 1 2 2 2 0 Haem-binding domain F-box-like PF12937.7 KXS13033.1 - 0.078 12.9 0.1 0.2 11.6 0.1 1.7 1 0 0 1 1 1 0 F-box-like zf-MYND PF01753.18 KXS13034.1 - 1.2e-06 28.5 6.0 2.2e-06 27.7 6.0 1.4 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KXS13034.1 - 0.11 12.8 7.7 0.19 12.1 7.7 1.4 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Gasdermin PF04598.12 KXS13035.1 - 0.15 11.5 0.0 0.18 11.2 0.0 1.1 1 0 0 1 1 1 0 Gasdermin pore forming domain Methyltransf_16 PF10294.9 KXS13036.1 - 3.1e-13 49.8 0.1 2.3e-12 47.0 0.1 2.1 1 1 0 1 1 1 1 Lysine methyltransferase Methyltransf_31 PF13847.6 KXS13036.1 - 0.085 12.7 0.2 0.47 10.3 0.2 1.9 1 1 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 KXS13036.1 - 0.11 11.8 0.2 0.42 9.9 0.1 1.8 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KXS13036.1 - 0.16 11.5 0.0 0.3 10.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_23 PF13489.6 KXS13036.1 - 0.2 11.5 0.0 0.41 10.4 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain DUF905 PF06006.12 KXS13037.1 - 0.045 13.7 0.1 6.1 6.9 0.1 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF905) SAE2 PF08573.10 KXS13038.1 - 1e-11 45.9 6.4 1e-11 45.9 6.4 4.6 4 2 0 4 4 4 1 DNA repair protein endonuclease SAE2/CtIP C-terminus DUF4407 PF14362.6 KXS13038.1 - 1 8.7 22.2 0.23 10.8 12.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) CYYR1 PF10873.8 KXS13039.1 - 0.017 15.6 3.1 0.017 15.6 3.1 1.7 2 0 0 2 2 2 0 Cysteine and tyrosine-rich protein 1 DUF2154 PF09922.9 KXS13039.1 - 0.08 12.8 0.0 0.31 10.9 0.0 1.8 2 0 0 2 2 2 0 Cell wall-active antibiotics response 4TMS YvqF GRA6 PF05084.13 KXS13042.1 - 0.076 13.0 0.0 0.18 11.7 0.0 1.6 2 0 0 2 2 2 0 Granule antigen protein (GRA6) SOG2 PF10428.9 KXS13042.1 - 8.1 5.5 8.9 13 4.9 8.9 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Phage_Nu1 PF07471.12 KXS13043.1 - 0.035 13.9 0.1 0.035 13.9 0.1 1.0 1 0 0 1 1 1 0 Phage DNA packaging protein Nu1 FliT PF05400.13 KXS13043.1 - 0.042 14.7 0.3 0.056 14.3 0.3 1.2 1 0 0 1 1 1 0 Flagellar protein FliT GAT PF03127.14 KXS13043.1 - 0.063 13.6 0.0 0.098 13.0 0.0 1.4 2 0 0 2 2 2 0 GAT domain LRR_6 PF13516.6 KXS13044.1 - 4.3e-05 23.2 14.3 1.6 9.0 0.0 6.1 5 1 0 5 5 5 4 Leucine Rich repeat Arm-DNA-bind_1 PF09003.10 KXS13044.1 - 0.17 12.0 2.2 15 5.8 0.0 3.3 3 1 1 4 4 4 0 Bacteriophage lambda integrase, Arm DNA-binding domain LRR_6 PF13516.6 KXS13045.1 - 1.5e-07 30.9 4.1 0.00021 21.1 0.1 2.4 2 0 0 2 2 2 2 Leucine Rich repeat LRR_4 PF12799.7 KXS13045.1 - 0.0027 18.1 0.0 0.0059 17.0 0.0 1.6 1 1 0 1 1 1 1 Leucine Rich repeats (2 copies) RCC1_2 PF13540.6 KXS13046.1 - 2.8e-07 30.2 17.2 1.7e-05 24.5 1.0 5.0 4 1 0 4 4 4 2 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 KXS13046.1 - 7.5e-07 29.7 30.9 0.0035 17.9 0.0 8.4 9 0 0 9 9 9 2 Regulator of chromosome condensation (RCC1) repeat AviRa PF11599.8 KXS13046.1 - 0.088 12.2 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 RRNA methyltransferase AviRa Glyoxalase_6 PF18029.1 KXS13047.1 - 1.2e-08 35.7 0.0 3.6e-07 30.9 0.0 2.4 2 0 0 2 2 2 1 Glyoxalase-like domain Glyoxalase PF00903.25 KXS13047.1 - 0.0022 18.2 0.0 1.9 8.7 0.0 3.2 3 0 0 3 3 3 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Ank_2 PF12796.7 KXS13048.1 - 2e-11 44.3 0.1 3.7e-06 27.4 0.4 3.0 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXS13048.1 - 4.3e-08 32.8 0.8 3.6 8.4 0.0 5.6 6 0 0 6 6 6 3 Ankyrin repeat Ank_4 PF13637.6 KXS13048.1 - 4.2e-07 30.4 0.5 1 10.0 0.1 4.4 4 1 0 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXS13048.1 - 4.9e-06 26.7 1.4 1.3 9.4 0.0 4.9 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank PF00023.30 KXS13048.1 - 6.9e-06 26.3 1.7 0.79 10.3 0.1 5.4 6 0 0 6 6 6 1 Ankyrin repeat TRAPPC9-Trs120 PF08626.11 KXS13052.1 - 6.8e-109 364.9 0.0 1.2e-44 152.1 0.0 6.4 5 2 0 5 5 5 5 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit TPR_16 PF13432.6 KXS13052.1 - 4.6 8.0 6.7 1.6 9.5 0.7 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat ABM PF03992.16 KXS13054.1 - 0.00056 20.0 0.0 0.0008 19.5 0.0 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase TrbC_Ftype PF09673.10 KXS13054.1 - 0.035 14.2 0.0 0.039 14.0 0.0 1.2 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin assembly protein LCCL PF03815.19 KXS13055.1 - 4.8e-16 58.6 0.0 8.7e-16 57.8 0.0 1.4 1 0 0 1 1 1 1 LCCL domain Rxt3 PF08642.10 KXS13055.1 - 0.0085 16.9 0.1 0.02 15.6 0.1 1.6 1 0 0 1 1 1 1 Histone deacetylation protein Rxt3 Ank_2 PF12796.7 KXS13057.1 - 0.00063 20.3 0.0 0.00063 20.3 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KXS13057.1 - 0.00073 19.9 0.1 0.0027 18.1 0.1 1.8 1 1 1 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 KXS13057.1 - 0.01 16.4 0.0 0.013 16.0 0.0 1.2 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXS13057.1 - 0.069 13.5 0.0 0.069 13.5 0.0 1.2 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Sel1 PF08238.12 KXS13058.1 - 1.7e-19 69.8 13.2 2.8e-06 27.8 1.3 4.8 5 0 0 5 5 5 3 Sel1 repeat HSP70 PF00012.20 KXS13059.1 - 4.1e-87 292.8 0.9 5.9e-87 292.3 0.3 1.4 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 KXS13059.1 - 5.2e-06 25.5 0.7 1.2e-05 24.3 0.7 1.5 1 0 0 1 1 1 1 MreB/Mbl protein BcrAD_BadFG PF01869.20 KXS13059.1 - 0.0033 17.0 0.6 0.23 10.9 0.1 2.1 2 0 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family FtsA PF14450.6 KXS13059.1 - 0.073 13.5 0.0 1.4 9.4 0.0 2.5 1 1 0 1 1 1 0 Cell division protein FtsA Ank_2 PF12796.7 KXS13060.1 - 2.2e-11 44.2 0.0 0.00073 20.1 0.0 4.0 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXS13060.1 - 3e-09 36.3 0.1 5.5 7.9 0.0 6.8 6 1 1 7 7 7 2 Ankyrin repeat Ank_4 PF13637.6 KXS13060.1 - 3.3e-05 24.3 0.0 2.8 8.6 0.0 4.8 2 2 3 5 5 5 1 Ankyrin repeats (many copies) Ank PF00023.30 KXS13060.1 - 3.9e-05 23.9 0.2 0.55 10.8 0.0 5.6 7 1 0 7 7 7 1 Ankyrin repeat Ank_5 PF13857.6 KXS13060.1 - 4e-05 23.8 0.0 2 8.8 0.0 4.4 4 0 0 4 4 4 1 Ankyrin repeats (many copies) TPP_enzyme_M PF00205.22 KXS13060.1 - 0.04 13.7 0.0 0.071 12.9 0.0 1.5 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, central domain S4 PF01479.25 KXS13060.1 - 0.12 12.2 0.5 0.31 10.8 0.1 1.9 2 0 0 2 2 2 0 S4 domain Fasciclin PF02469.22 KXS13061.1 - 5e-07 30.0 0.1 1.7e-06 28.3 0.1 1.8 1 1 0 1 1 1 1 Fasciclin domain Pox_VLTF3 PF04947.14 KXS13062.1 - 0.0066 16.2 0.0 0.0067 16.2 0.0 1.1 1 0 0 1 1 1 1 Poxvirus Late Transcription Factor VLTF3 like Rrp44_CSD1 PF17216.3 KXS13063.1 - 0.11 12.2 0.2 0.12 12.1 0.2 1.2 1 0 0 1 1 1 0 Rrp44-like cold shock domain PGC7_Stella PF15549.6 KXS13064.1 - 0.071 13.1 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 PGC7/Stella/Dppa3 domain WD40 PF00400.32 KXS13065.1 - 4.9e-13 49.3 11.8 2e-05 25.2 0.0 6.6 7 0 0 7 7 7 3 WD domain, G-beta repeat eIF2A PF08662.11 KXS13065.1 - 0.0022 17.9 0.0 0.037 13.9 0.0 2.3 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 KXS13065.1 - 0.0041 17.4 0.0 2.2 8.6 0.0 3.5 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KXS13065.1 - 0.061 13.3 2.9 4 7.5 0.1 3.6 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat LisH PF08513.11 KXS13065.1 - 0.13 12.3 0.1 0.24 11.4 0.1 1.5 1 0 0 1 1 1 0 LisH LRAT PF04970.13 KXS13069.1 - 3.8e-08 33.7 0.0 5.9e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Lecithin retinol acyltransferase DUF1175 PF06672.11 KXS13069.1 - 0.02 14.6 0.0 0.035 13.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1175) Amidase_6 PF12671.7 KXS13069.1 - 0.081 13.0 0.5 0.13 12.4 0.1 1.5 2 0 0 2 2 2 0 Putative amidase domain DDE_Tnp_4 PF13359.6 KXS13070.1 - 1.4e-12 47.6 0.0 1.9e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Keratin PF02422.16 KXS13070.1 - 0.17 11.6 0.0 0.3 10.8 0.0 1.3 1 0 0 1 1 1 0 Keratin HMG_box PF00505.19 KXS13071.1 - 2.2e-09 37.6 0.1 2.2e-09 37.6 0.1 2.7 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KXS13071.1 - 0.0043 17.6 0.0 0.0043 17.6 0.0 2.6 2 0 0 2 2 2 1 HMG-box domain AT_hook PF02178.19 KXS13071.1 - 1.6 8.8 8.4 0.24 11.4 3.8 2.2 2 0 0 2 2 2 0 AT hook motif Capsid_NCLDV PF04451.12 KXS13073.1 - 7.2e-35 120.6 0.0 1.1e-34 119.9 0.0 1.3 1 0 0 1 1 1 1 Large eukaryotic DNA virus major capsid protein Capsid_N PF16903.5 KXS13073.1 - 4.6e-15 55.8 2.8 7.5e-15 55.1 0.4 2.1 1 1 1 2 2 2 1 Major capsid protein N-terminus Stig1 PF04885.13 KXS13074.1 - 1.9 9.0 37.9 0.3 11.5 9.5 3.4 3 1 1 4 4 4 0 Stigma-specific protein, Stig1 FoP_duplication PF13865.6 KXS13075.1 - 0.013 16.1 15.9 0.032 14.8 15.9 1.6 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Endonuclease_7 PF02945.15 KXS13075.1 - 0.047 13.6 0.3 15 5.6 0.1 2.5 2 0 0 2 2 2 0 Recombination endonuclease VII Ecl1 PF12855.7 KXS13076.1 - 1.1e-09 39.7 17.7 1.9e-09 38.9 17.7 1.4 1 1 0 1 1 1 1 ECL1/2/3 zinc binding proteins DUF5440 PF17509.2 KXS13076.1 - 0.047 13.3 0.0 0.078 12.6 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5440) DUF2116 PF09889.9 KXS13076.1 - 0.19 11.7 2.0 0.32 11.0 2.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) BC10 PF06726.12 KXS13077.1 - 8.2e-13 48.4 6.9 1.6e-12 47.5 6.9 1.5 1 0 0 1 1 1 1 Bladder cancer-related protein BC10 Pex14_N PF04695.13 KXS13077.1 - 0.06 14.0 3.5 0.088 13.5 3.5 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Sporozoite_P67 PF05642.11 KXS13077.1 - 0.094 10.8 12.4 0.12 10.4 12.4 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Plasmodium_Vir PF05795.11 KXS13077.1 - 0.33 10.3 1.3 0.44 9.9 1.3 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF3300 PF11737.8 KXS13079.1 - 0.0028 17.3 0.1 0.0036 16.9 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3300) Glyco_hydro_26 PF02156.15 KXS13080.1 - 2.9e-10 40.1 5.3 7.6e-07 28.9 0.1 2.2 2 0 0 2 2 2 2 Glycosyl hydrolase family 26 EF-hand_1 PF00036.32 KXS13080.1 - 0.18 11.4 0.2 0.79 9.4 0.1 1.9 2 0 0 2 2 2 0 EF hand Ribo_biogen_C PF04034.13 KXS13081.1 - 6.5e-49 164.9 0.0 8.7e-49 164.5 0.0 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 KXS13081.1 - 6.1e-12 45.1 0.0 9.6e-12 44.5 0.0 1.3 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI DUF2201_N PF13203.6 KXS13081.1 - 0.33 10.5 4.8 0.56 9.8 4.8 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain DIOX_N PF14226.6 KXS13082.1 - 4.3e-35 121.0 0.0 9.8e-35 119.9 0.0 1.6 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KXS13082.1 - 1.1e-16 61.1 0.0 2.7e-16 59.9 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily NopRA1 PF16201.5 KXS13082.1 - 0.18 11.3 0.0 0.28 10.7 0.0 1.2 1 0 0 1 1 1 0 Nucleolar pre-ribosomal-associated protein 1 DUF2985 PF11204.8 KXS13083.1 - 2e-10 40.7 1.7 2e-10 40.7 1.7 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2985) Dynamin_M PF01031.20 KXS13084.1 - 1.1e-80 271.0 0.2 2.2e-80 269.9 0.0 1.6 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 KXS13084.1 - 1.4e-52 178.1 0.0 2.9e-52 177.1 0.0 1.5 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 KXS13084.1 - 4e-20 71.8 1.4 1.1e-19 70.3 1.4 1.8 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KXS13084.1 - 1.8e-05 24.8 0.2 0.0001 22.3 0.2 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 KXS13084.1 - 0.16 12.2 0.0 0.39 10.9 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase V-SNARE PF05008.15 KXS13084.1 - 0.26 11.7 0.8 2.8 8.4 0.0 2.4 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus AAA_15 PF13175.6 KXS13084.1 - 0.32 10.7 4.3 0.26 10.9 0.2 2.3 2 1 0 2 2 2 0 AAA ATPase domain Gelsolin PF00626.22 KXS13085.1 - 1.4e-43 146.7 0.0 6.2e-15 54.9 0.0 3.4 3 0 0 3 3 3 3 Gelsolin repeat DUF1761 PF08570.10 KXS13086.1 - 1.1e-08 35.4 0.0 1.3e-08 35.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1761) Abhydrolase_1 PF00561.20 KXS13087.1 - 9.5e-30 104.1 0.1 2.2e-29 102.9 0.1 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXS13087.1 - 6.3e-10 40.0 7.2 1.2e-09 39.1 7.2 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXS13087.1 - 1.7e-09 37.3 0.0 3.4e-06 26.5 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 KXS13087.1 - 0.047 13.8 0.0 0.085 13.0 0.0 1.3 1 0 0 1 1 1 0 TAP-like protein Glyco_hydro_3_C PF01915.22 KXS13088.1 - 5.3e-52 176.8 0.0 8.7e-52 176.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KXS13088.1 - 1.7e-44 152.5 0.0 2.5e-44 151.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KXS13088.1 - 1.6e-20 73.0 0.4 5.4e-20 71.3 0.1 2.1 2 0 0 2 2 2 1 Fibronectin type III-like domain fn3_5 PF06280.12 KXS13088.1 - 0.14 12.8 0.0 0.29 11.8 0.0 1.5 1 0 0 1 1 1 0 Fn3-like domain Glyco_hydro_3_C PF01915.22 KXS13090.1 - 1.1e-52 178.9 0.1 2.2e-52 178.0 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KXS13090.1 - 4e-42 144.7 0.0 1.3e-41 143.0 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KXS13090.1 - 5.1e-21 74.6 0.1 1.2e-20 73.4 0.1 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain PP2C PF00481.21 KXS13091.1 - 1.5e-48 165.7 0.0 1.8e-48 165.4 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 KXS13091.1 - 1.9e-05 24.4 0.1 3.5e-05 23.6 0.1 1.4 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 KXS13091.1 - 0.0064 16.4 0.0 0.028 14.3 0.0 1.9 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) DUF4236 PF14020.6 KXS13091.1 - 0.91 10.1 5.8 0.3 11.7 1.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4236) zf-CCCH_4 PF18044.1 KXS13093.1 - 2.6e-16 59.0 14.5 4.6e-08 32.7 4.8 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KXS13093.1 - 7e-16 57.7 18.9 4.2e-08 33.0 5.3 2.3 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH PF00642.24 KXS13093.1 - 7.9e-15 54.3 13.9 3.6e-07 29.9 3.1 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 KXS13093.1 - 8.6e-10 39.3 5.0 6.4e-05 23.6 0.8 2.3 2 0 0 2 2 2 2 Torus domain zf-CCCH_2 PF14608.6 KXS13093.1 - 0.0016 18.9 2.5 0.0016 18.9 2.5 2.6 3 0 0 3 3 3 2 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 KXS13093.1 - 0.2 11.9 4.3 8.4 6.7 0.7 2.2 2 0 0 2 2 2 0 Zinc-finger containing family Gram_pos_anchor PF00746.21 KXS13094.1 - 0.22 11.5 2.8 0.76 9.8 2.8 2.0 1 0 0 1 1 1 0 LPXTG cell wall anchor motif Podoplanin PF05808.11 KXS13094.1 - 0.35 10.9 8.2 0.99 9.5 8.2 1.7 1 1 0 1 1 1 0 Podoplanin bZIP_1 PF00170.21 KXS13095.1 - 2.2e-08 34.1 6.0 2.2e-08 34.1 6.0 1.8 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KXS13095.1 - 1.2e-05 25.3 4.7 1.2e-05 25.3 4.7 2.0 1 1 1 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 KXS13095.1 - 0.036 14.6 5.8 0.1 13.1 5.7 1.8 1 1 0 1 1 1 0 bZIP Maf transcription factor Peptidase_M1 PF01433.20 KXS13096.1 - 9.3e-44 149.6 0.0 1.3e-43 149.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 KXS13096.1 - 1.8e-35 121.4 0.0 2.8e-35 120.8 0.0 1.3 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 KXS13096.1 - 1.6e-20 74.0 0.0 2.4e-20 73.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_MA_2 PF13485.6 KXS13096.1 - 0.068 12.8 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Peptidase MA superfamily DUF4407 PF14362.6 KXS13097.1 - 0.32 10.3 2.7 2.3 7.5 1.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DBINO PF13892.6 KXS13097.1 - 1.7 9.0 5.1 3 8.2 5.1 1.4 1 0 0 1 1 1 0 DNA-binding domain Peptidase_C42 PF05533.12 KXS13098.1 - 0.05 13.6 0.0 0.8 9.8 0.0 2.1 2 0 0 2 2 2 0 Beet yellows virus-type papain-like endopeptidase C42 Acetyltransf_1 PF00583.25 KXS13100.1 - 3e-06 27.4 0.0 4.8e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXS13100.1 - 0.00019 21.4 0.0 0.00034 20.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.7 KXS13100.1 - 0.0017 18.5 0.4 0.0037 17.4 0.1 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXS13100.1 - 0.02 15.3 0.0 0.036 14.5 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KXS13100.1 - 0.083 13.0 0.1 0.15 12.2 0.1 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.7 KXS13100.1 - 0.089 12.9 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Glyco_hydro_125 PF06824.11 KXS13102.1 - 1.9e-143 478.3 0.0 2.2e-143 478.1 0.0 1.0 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) Exo_endo_phos PF03372.23 KXS13103.1 - 9.5e-12 44.9 2.4 3.8e-11 43.0 2.4 2.0 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RGS PF00615.19 KXS13104.1 - 0.0048 17.2 0.0 0.011 16.0 0.0 1.7 1 1 0 1 1 1 1 Regulator of G protein signaling domain UPF0047 PF01894.17 KXS13105.1 - 1.7e-38 131.3 0.0 2e-38 131.1 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 zf-4CXXC_R1 PF10497.9 KXS13106.1 - 1.2e-21 76.7 6.4 1.3e-12 47.8 0.9 2.5 2 0 0 2 2 2 2 Zinc-finger domain of monoamine-oxidase A repressor R1 Rubredoxin_2 PF18073.1 KXS13106.1 - 0.014 15.1 2.6 0.014 15.1 2.6 2.3 2 0 0 2 2 2 0 Rubredoxin metal binding domain RINGv PF12906.7 KXS13107.1 - 0.00059 19.9 3.7 0.0015 18.6 3.7 1.7 1 1 0 1 1 1 1 RING-variant domain FAD_binding_3 PF01494.19 KXS13109.1 - 1.3e-34 120.0 0.0 4.5e-25 88.6 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.17 KXS13109.1 - 0.0074 15.6 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 KXS13109.1 - 0.19 10.7 0.1 0.88 8.5 0.1 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein F-box-like PF12937.7 KXS13110.1 - 1.1e-06 28.4 1.0 4.2e-06 26.5 0.3 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KXS13110.1 - 0.0013 18.5 0.3 0.0013 18.5 0.3 2.5 2 1 0 2 2 2 1 F-box domain LRR_6 PF13516.6 KXS13110.1 - 0.089 12.9 0.2 0.98 9.6 0.2 2.6 2 0 0 2 2 2 0 Leucine Rich repeat RCC1 PF00415.18 KXS13111.1 - 2.4e-26 92.1 4.3 2e-05 25.1 0.0 5.8 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 KXS13111.1 - 6.6e-25 87.5 0.1 5.3e-11 42.7 0.1 3.3 2 1 1 3 3 3 2 BTB/POZ domain RCC1_2 PF13540.6 KXS13111.1 - 2e-19 68.9 16.6 7e-06 25.7 0.0 7.9 8 0 0 8 8 8 4 Regulator of chromosome condensation (RCC1) repeat Ank_4 PF13637.6 KXS13111.1 - 2e-11 44.2 0.0 0.00082 19.9 0.0 4.3 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXS13111.1 - 3.6e-11 43.5 0.0 3.4e-09 37.2 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXS13111.1 - 1.2e-10 41.4 0.7 3e-05 24.2 0.0 3.6 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 KXS13111.1 - 5.8e-07 29.7 3.6 0.025 15.0 0.1 4.6 5 0 0 5 5 5 2 Ankyrin repeat Ank_3 PF13606.6 KXS13111.1 - 1e-06 28.6 0.0 0.17 12.5 0.0 4.5 4 0 0 4 4 4 2 Ankyrin repeat PUF PF00806.19 KXS13112.1 - 7.8e-69 223.7 9.3 1e-09 37.5 0.0 8.3 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat sCache_2 PF17200.4 KXS13112.1 - 0.013 15.3 0.5 14 5.5 0.0 4.0 5 0 0 5 5 5 0 Single Cache domain 2 DUF4821 PF16092.5 KXS13112.1 - 0.072 12.7 0.2 12 5.4 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4821) DUF445 PF04286.12 KXS13112.1 - 0.16 11.7 0.1 0.37 10.5 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF445) RraA-like PF03737.15 KXS13112.1 - 0.19 11.9 0.4 44 4.2 0.1 3.1 2 1 0 3 3 3 0 Aldolase/RraA Elong_Iki1 PF10483.9 KXS13113.1 - 2.6e-16 60.0 0.0 2.7e-08 33.7 0.2 2.1 1 1 1 2 2 2 2 Elongator subunit Iki1 OCD_Mu_crystall PF02423.15 KXS13114.1 - 8.6e-40 136.6 0.6 6.6e-39 133.7 0.6 1.9 1 1 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.20 KXS13114.1 - 4.3e-06 26.8 0.0 7.4e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NOC3p PF07540.11 KXS13115.1 - 3.1e-19 69.2 0.0 1e-18 67.6 0.0 1.9 2 0 0 2 2 2 1 Nucleolar complex-associated protein CBF PF03914.17 KXS13115.1 - 8.4e-11 42.2 0.1 2.1e-10 40.9 0.1 1.7 1 0 0 1 1 1 1 CBF/Mak21 family ATP_sub_h PF10775.9 KXS13115.1 - 0.037 14.0 1.5 0.14 12.2 1.5 2.0 1 0 0 1 1 1 0 ATP synthase complex subunit h DUF4407 PF14362.6 KXS13115.1 - 0.88 8.9 5.2 1.6 8.0 5.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Thg1 PF04446.12 KXS13116.1 - 1e-29 103.1 0.0 6e-21 74.8 0.0 2.2 2 0 0 2 2 2 2 tRNAHis guanylyltransferase CCDC23 PF15674.5 KXS13116.1 - 0.12 12.4 0.0 0.32 11.0 0.0 1.7 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 23 FMN_dh PF01070.18 KXS13117.1 - 2.7e-125 418.0 0.6 3.3e-125 417.7 0.6 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KXS13117.1 - 1.1e-22 79.9 0.0 2.3e-22 78.9 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 KXS13117.1 - 2.7e-08 33.3 0.1 4.7e-08 32.6 0.1 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 KXS13117.1 - 3.1e-05 23.1 0.5 6.2e-05 22.2 0.4 1.5 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.14 KXS13117.1 - 0.0058 16.0 0.1 1.8 7.8 0.1 2.3 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG NMO PF03060.15 KXS13117.1 - 0.023 14.1 0.1 0.031 13.7 0.1 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase His_biosynth PF00977.21 KXS13117.1 - 0.036 13.5 0.1 0.12 11.8 0.1 1.8 1 1 0 1 1 1 0 Histidine biosynthesis protein RGS PF00615.19 KXS13118.1 - 1e-16 61.3 0.2 2.5e-15 56.8 0.2 2.1 1 1 0 1 1 1 1 Regulator of G protein signaling domain Succ_DH_flav_C PF02910.20 KXS13118.1 - 0.072 13.1 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Fumarate reductase flavoprotein C-term PFL-like PF02901.15 KXS13119.1 - 1.6e-194 648.3 0.0 2.6e-194 647.5 0.0 1.3 1 0 0 1 1 1 1 Pyruvate formate lyase-like Gly_radical PF01228.21 KXS13119.1 - 2.7e-41 140.4 0.0 5.1e-41 139.5 0.0 1.5 1 0 0 1 1 1 1 Glycine radical DUF3029 PF11230.8 KXS13119.1 - 0.022 13.1 0.0 0.04 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3029) Radical_SAM PF04055.21 KXS13120.1 - 9.6e-17 61.9 0.0 1.3e-16 61.4 0.0 1.2 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 KXS13120.1 - 4.9e-14 52.8 0.0 7.8e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 KXS13120.1 - 9e-06 25.8 0.0 1.6e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain HrpB7 PF09486.10 KXS13121.1 - 0.00032 21.1 7.0 0.0033 17.8 3.9 2.3 2 0 0 2 2 2 1 Bacterial type III secretion protein (HrpB7) PKcGMP_CC PF16808.5 KXS13121.1 - 0.0028 17.4 3.4 1.6 8.6 0.1 2.6 1 1 1 2 2 2 2 Coiled-coil N-terminus of cGMP-dependent protein kinase LemA PF04011.12 KXS13121.1 - 0.027 14.3 0.6 4 7.3 0.1 2.6 2 1 0 2 2 2 0 LemA family DLP_helical PF18709.1 KXS13121.1 - 0.058 12.6 2.4 0.11 11.7 2.4 1.5 1 0 0 1 1 1 0 Dynamin-like helical domain DUF4763 PF15960.5 KXS13121.1 - 0.12 11.6 9.1 0.023 14.0 3.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4763) V_ATPase_I PF01496.19 KXS13121.1 - 0.13 10.1 1.8 0.19 9.6 1.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DHR10 PF18595.1 KXS13121.1 - 0.27 11.3 11.1 0.094 12.8 5.8 2.1 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain Exonuc_VII_L PF02601.15 KXS13121.1 - 0.31 10.6 7.3 0.023 14.3 2.5 1.6 2 0 0 2 2 2 0 Exonuclease VII, large subunit Spc7 PF08317.11 KXS13121.1 - 0.51 9.2 9.6 0.088 11.7 4.7 1.9 2 0 0 2 2 2 0 Spc7 kinetochore protein GrpE PF01025.19 KXS13121.1 - 1 9.0 8.6 0.37 10.5 3.9 2.0 2 0 0 2 2 2 0 GrpE Tropomyosin_1 PF12718.7 KXS13121.1 - 1.1 9.4 10.0 0.18 11.9 6.1 1.8 2 1 0 2 2 2 0 Tropomyosin like TMF_DNA_bd PF12329.8 KXS13121.1 - 1.5 8.8 10.2 0.89 9.6 7.2 1.9 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF724 PF05266.14 KXS13121.1 - 2.2 8.1 8.1 0.63 9.8 4.8 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DUF3450 PF11932.8 KXS13121.1 - 7.4 5.8 11.2 4.2 6.6 6.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Golgin_A5 PF09787.9 KXS13122.1 - 0.00026 20.6 13.6 0.00026 20.6 13.6 2.0 1 1 1 2 2 2 1 Golgin subfamily A member 5 TMF_DNA_bd PF12329.8 KXS13122.1 - 0.0043 17.0 7.5 0.07 13.1 0.2 2.9 2 0 0 2 2 2 1 TATA element modulatory factor 1 DNA binding Bacillus_HBL PF05791.11 KXS13122.1 - 0.0049 16.7 0.7 0.01 15.7 0.7 1.5 1 0 0 1 1 1 1 Bacillus haemolytic enterotoxin (HBL) ArgJ PF01960.18 KXS13122.1 - 0.055 12.2 0.2 0.095 11.4 0.2 1.3 1 0 0 1 1 1 0 ArgJ family GAS PF13851.6 KXS13122.1 - 0.16 11.3 14.6 0.029 13.7 6.3 2.8 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding BBP1_C PF15272.6 KXS13122.1 - 0.17 11.7 11.4 0.55 10.0 10.4 2.2 1 1 1 2 2 2 0 Spindle pole body component BBP1, C-terminal Med9 PF07544.13 KXS13122.1 - 0.17 12.0 6.3 1.8 8.7 0.8 3.1 1 1 2 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Tup_N PF08581.10 KXS13122.1 - 0.3 11.4 14.2 0.14 12.4 6.3 3.2 3 0 0 3 3 3 0 Tup N-terminal DUF3450 PF11932.8 KXS13122.1 - 0.35 10.1 22.7 0.03 13.6 2.2 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) ABC_tran_CTD PF16326.5 KXS13122.1 - 0.77 10.1 19.9 0.08 13.2 2.4 3.1 2 1 1 3 3 3 0 ABC transporter C-terminal domain CytochromB561_N PF09786.9 KXS13122.1 - 0.94 8.4 12.3 0.23 10.4 4.3 2.1 2 0 0 2 2 2 0 Cytochrome B561, N terminal Csm1_N PF18504.1 KXS13122.1 - 1.6 9.1 15.5 0.88 10.0 0.3 4.3 2 1 3 5 5 5 0 Csm1 N-terminal domain Spc7 PF08317.11 KXS13122.1 - 1.8 7.4 19.2 0.47 9.3 14.5 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein Jnk-SapK_ap_N PF09744.9 KXS13122.1 - 3.1 8.0 26.1 8.5 6.6 4.9 3.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 APG6_N PF17675.1 KXS13122.1 - 4.8 7.7 26.5 0.35 11.4 2.8 2.8 1 1 1 2 2 2 0 Apg6 coiled-coil region V_ATPase_I PF01496.19 KXS13122.1 - 7.5 4.3 6.5 9.8 3.9 6.5 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family BB_PF PF18063.1 KXS13123.1 - 4.3e-27 95.0 1.9 1.3e-26 93.5 1.3 1.8 2 0 0 2 2 2 1 Beta barrel Pore-forming domain Fungal_KA1 PF16797.5 KXS13123.1 - 0.051 13.3 0.1 0.097 12.4 0.1 1.5 1 0 0 1 1 1 0 Fungal kinase associated-1 domain Med21 PF11221.8 KXS13124.1 - 0.27 11.5 4.2 0.13 12.6 1.1 2.1 2 1 0 2 2 2 0 Subunit 21 of Mediator complex UBA2_C PF16195.5 KXS13124.1 - 1.3 9.8 11.9 0.32 11.7 7.8 2.1 1 1 0 1 1 1 0 SUMO-activating enzyme subunit 2 C-terminus RNA_pol_Rpb1_5 PF04998.17 KXS13125.1 - 3.5e-09 36.5 0.2 4.5e-09 36.1 0.2 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 DUF4056 PF13265.6 KXS13125.1 - 0.11 11.8 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4056) PS_pyruv_trans PF04230.13 KXS13127.1 - 0.035 14.0 0.1 0.073 13.0 0.1 1.5 1 0 0 1 1 1 0 Polysaccharide pyruvyl transferase Pox_VLTF3 PF04947.14 KXS13128.1 - 4.1e-07 29.9 0.0 7.1e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Poxvirus Late Transcription Factor VLTF3 like TF_Zn_Ribbon PF08271.12 KXS13128.1 - 0.00018 21.0 1.3 0.00035 20.0 1.3 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding Methyltransf_24 PF13578.6 KXS13129.1 - 1.7e-07 32.2 0.1 4.1e-07 31.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain AcetylCoA_hyd_C PF13336.6 KXS13132.1 - 6e-57 191.9 0.0 8.9e-57 191.3 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain AcetylCoA_hydro PF02550.15 KXS13132.1 - 7.8e-18 65.2 0.0 1.3e-17 64.5 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain EI24 PF07264.11 KXS13133.1 - 0.0028 17.9 6.4 0.0028 17.9 6.4 2.6 2 1 0 2 2 2 2 Etoposide-induced protein 2.4 (EI24) ADH_N PF08240.12 KXS13135.1 - 1.8e-07 31.0 0.0 3.3e-06 27.0 0.0 2.5 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 KXS13135.1 - 2.8e-05 23.7 0.1 0.017 14.6 0.2 2.3 2 0 0 2 2 2 2 Glucose dehydrogenase C-terminus ADH_zinc_N PF00107.26 KXS13135.1 - 0.086 12.8 0.1 0.35 10.9 0.1 2.1 1 1 0 1 1 1 0 Zinc-binding dehydrogenase DUF1298 PF06974.13 KXS13136.1 - 4.9e-15 55.7 0.0 7.8e-15 55.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1298) WES_acyltransf PF03007.16 KXS13136.1 - 0.0041 16.9 0.0 0.0072 16.1 0.0 1.4 1 0 0 1 1 1 1 Wax ester synthase-like Acyl-CoA acyltransferase domain TraL PF07178.11 KXS13138.1 - 0.16 12.5 0.6 0.5 10.9 0.1 2.0 1 1 1 2 2 2 0 TraL protein Sedlin_N PF04628.13 KXS13140.1 - 0.0094 16.1 0.0 0.013 15.6 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Es2 PF09751.9 KXS13141.1 - 1.3e-66 226.1 0.0 1.8e-66 225.7 0.0 1.1 1 0 0 1 1 1 1 Nuclear protein Es2 MFS_1 PF07690.16 KXS13142.1 - 1.1e-11 44.3 24.7 1.1e-11 44.3 24.7 2.3 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF5538 PF17692.1 KXS13142.1 - 0.5 10.4 4.1 1 9.4 4.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5538) DEAD PF00270.29 KXS13144.1 - 2.1e-44 151.4 0.0 3.7e-44 150.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXS13144.1 - 3.4e-27 95.0 0.0 7.7e-27 93.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXS13144.1 - 0.00034 20.7 0.0 0.00055 20.0 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KXS13144.1 - 0.037 14.3 0.2 7.1 6.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain VSP PF03302.13 KXS13145.1 - 4.2 6.1 12.8 11 4.7 12.8 1.7 1 1 0 1 1 1 0 Giardia variant-specific surface protein Podoplanin PF05808.11 KXS13145.1 - 6.5 6.8 6.6 15 5.7 6.4 1.6 1 1 0 1 1 1 0 Podoplanin YmgB PF10798.8 KXS13146.1 - 0.11 12.4 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Biofilm development protein YmgB/AriR F-box-like PF12937.7 KXS13149.1 - 1.1e-06 28.4 0.0 2.4e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXS13149.1 - 0.019 14.8 0.0 0.033 14.1 0.0 1.4 1 0 0 1 1 1 0 F-box domain adh_short PF00106.25 KXS13151.1 - 5.7e-25 87.9 0.5 9.1e-15 54.6 0.0 2.6 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXS13151.1 - 3.7e-12 46.3 1.0 5.1e-08 32.8 0.1 2.8 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase THF_DHG_CYH_C PF02882.19 KXS13151.1 - 0.0062 15.9 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain KR PF08659.10 KXS13151.1 - 0.041 13.8 0.8 0.7 9.8 0.3 2.3 2 0 0 2 2 2 0 KR domain DUF3757 PF12582.8 KXS13151.1 - 0.11 12.9 0.0 0.23 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3757) DDE_Tnp_4 PF13359.6 KXS13155.1 - 8.3e-13 48.3 0.0 9.8e-13 48.1 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Histidinol_dh PF00815.20 KXS13155.1 - 0.26 10.3 0.0 0.32 10.0 0.0 1.1 1 0 0 1 1 1 0 Histidinol dehydrogenase HMG_box PF00505.19 KXS13156.1 - 7.7e-08 32.6 2.4 1.4e-07 31.8 0.0 2.4 2 0 0 2 2 2 1 HMG (high mobility group) box MFS_1 PF07690.16 KXS13157.1 - 1.1e-19 70.6 29.7 2.1e-19 69.7 14.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KXS13157.1 - 2.4e-10 39.6 1.3 2.4e-10 39.6 1.3 3.0 2 1 1 3 3 3 2 MFS/sugar transport protein Sec15 PF04091.12 KXS13158.1 - 2.1e-89 300.1 1.0 3.8e-89 299.2 1.0 1.4 1 0 0 1 1 1 1 Exocyst complex subunit Sec15-like DUF4055 PF13264.6 KXS13158.1 - 0.23 11.6 2.9 0.18 12.0 0.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4055) Sec8_exocyst PF04048.14 KXS13158.1 - 0.27 11.1 6.6 0.078 12.9 0.7 2.7 3 0 0 3 3 3 0 Sec8 exocyst complex component specific domain PB1 PF00564.24 KXS13162.1 - 0.00012 22.0 0.0 0.00026 20.9 0.0 1.6 1 0 0 1 1 1 1 PB1 domain QWRF PF04484.12 KXS13165.1 - 0.88 9.3 4.6 0.95 9.1 4.6 1.1 1 0 0 1 1 1 0 QWRF family Ecm33 PF12454.8 KXS13167.1 - 0.59 10.3 2.1 1.3 9.2 2.1 1.5 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein Methyltransf_23 PF13489.6 KXS13168.1 - 0.17 11.7 0.0 0.32 10.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Glyco_hydro_26 PF02156.15 KXS13171.1 - 0.085 12.3 1.9 0.19 11.1 0.1 1.9 1 1 1 2 2 2 0 Glycosyl hydrolase family 26 SNF5 PF04855.12 KXS13172.1 - 1.5e-15 57.6 0.0 2.6e-15 56.9 0.0 1.3 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 SNF5 PF04855.12 KXS13173.1 - 4.4e-25 88.9 0.0 6.7e-25 88.3 0.0 1.3 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 Nudix_N_2 PF14803.6 KXS13173.1 - 1.6 8.7 4.4 2.4 8.1 1.4 2.5 2 0 0 2 2 2 0 Nudix N-terminal Carboxyl_trans PF01039.22 KXS13174.1 - 3.3e-35 121.7 0.3 4.2e-30 104.8 0.4 3.1 2 1 0 2 2 2 2 Carboxyl transferase domain CPSase_L_D2 PF02786.17 KXS13174.1 - 3.8e-34 118.0 0.0 4.1e-18 65.7 0.1 2.5 1 1 1 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 KXS13174.1 - 2.8e-26 92.2 0.1 6.5e-14 52.4 0.1 3.0 2 1 1 3 3 3 2 Biotin carboxylase, N-terminal domain Biotin_lipoyl PF00364.22 KXS13174.1 - 1.5e-08 34.4 0.8 3.5e-08 33.2 0.8 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_carb_C PF02785.19 KXS13174.1 - 2.3e-08 34.1 0.0 8.5e-08 32.3 0.0 2.0 1 1 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl_2 PF13533.6 KXS13174.1 - 0.0042 16.9 0.2 0.01 15.7 0.2 1.6 1 0 0 1 1 1 1 Biotin-lipoyl like RnfC_N PF13375.6 KXS13174.1 - 0.016 15.1 0.4 0.037 14.0 0.4 1.5 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain zf-UBP PF02148.19 KXS13175.1 - 7.6e-15 55.0 4.5 1.6e-14 54.0 4.5 1.4 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein F-box-like PF12937.7 KXS13175.1 - 0.00012 21.9 3.3 0.00019 21.2 0.8 2.6 2 1 1 3 3 3 1 F-box-like F-box PF00646.33 KXS13175.1 - 0.046 13.6 0.1 0.14 12.1 0.1 1.9 1 1 0 1 1 1 0 F-box domain DUSP PF06337.12 KXS13175.1 - 0.09 13.4 0.0 0.16 12.6 0.0 1.4 1 0 0 1 1 1 0 DUSP domain FYDLN_acid PF09538.10 KXS13175.1 - 0.15 12.7 3.5 0.27 11.9 3.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) AhpC-TSA_2 PF13911.6 KXS13176.1 - 7.5e-11 42.2 0.0 1.1e-10 41.6 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 KXS13176.1 - 0.015 15.2 0.0 0.022 14.7 0.0 1.2 1 0 0 1 1 1 0 AhpC/TSA family Redoxin PF08534.10 KXS13176.1 - 0.081 12.6 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Redoxin Kinesin PF00225.23 KXS13177.1 - 9.7e-82 274.6 0.0 1.2e-81 274.3 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KXS13177.1 - 5.3e-17 62.1 0.0 2.6e-13 50.2 0.0 2.2 2 0 0 2 2 2 2 Microtubule binding ABC_tran PF00005.27 KXS13178.1 - 1.5e-33 116.2 0.0 3.5e-33 115.0 0.0 1.7 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 KXS13178.1 - 3e-27 96.0 0.0 1.7e-12 47.6 0.0 2.3 1 1 1 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 KXS13178.1 - 6.1e-07 29.1 0.1 9.3e-05 22.0 0.0 2.3 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 KXS13178.1 - 0.00014 20.8 0.1 0.0014 17.5 0.0 2.0 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_22 PF13401.6 KXS13178.1 - 0.00019 21.7 0.5 0.0026 18.0 0.5 2.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KXS13178.1 - 0.0013 19.1 0.0 0.0038 17.6 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 KXS13178.1 - 0.006 16.3 0.1 0.014 15.1 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.6 KXS13178.1 - 0.0065 16.1 0.1 0.062 12.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 KXS13178.1 - 0.013 14.7 0.9 0.053 12.8 0.0 2.3 3 0 0 3 3 3 0 Zeta toxin RsgA_GTPase PF03193.16 KXS13178.1 - 0.014 15.3 0.0 0.029 14.3 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_30 PF13604.6 KXS13178.1 - 0.03 14.1 0.3 0.59 9.8 0.3 2.6 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KXS13178.1 - 0.038 13.9 0.1 0.89 9.5 0.0 2.4 2 0 0 2 2 2 0 NTPase DEAD PF00270.29 KXS13178.1 - 0.048 13.4 0.0 5.5 6.7 0.0 2.2 2 0 0 2 2 2 0 DEAD/DEAH box helicase Imm75 PF15660.6 KXS13178.1 - 0.12 12.7 0.0 0.33 11.2 0.0 1.8 1 0 0 1 1 1 0 Putative Immunity protein 75 AAA_7 PF12775.7 KXS13178.1 - 0.18 11.3 0.0 0.33 10.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Bot1p PF12298.8 KXS13179.1 - 1.5e-11 44.8 0.0 1.7e-11 44.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic mitochondrial regulator protein MRP-L20 PF12824.7 KXS13179.1 - 2.6e-05 24.5 0.0 2.9e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 UPF0240 PF06784.11 KXS13179.1 - 0.007 16.4 0.0 0.0079 16.3 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0240) HTH_32 PF13565.6 KXS13179.1 - 0.11 13.2 0.1 0.13 12.9 0.1 1.2 1 0 0 1 1 1 0 Homeodomain-like domain Ferric_reduct PF01794.19 KXS13180.1 - 1.2e-13 51.3 6.8 1.2e-13 51.3 6.8 3.0 2 1 1 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KXS13180.1 - 1.1e-06 28.7 0.0 2.1e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 KXS13180.1 - 0.00064 20.3 0.0 0.2 12.3 0.0 2.3 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 KXS13180.1 - 0.0028 17.8 0.0 1.1 9.4 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain DAO PF01266.24 KXS13181.1 - 9.1e-48 163.6 7.1 9.1e-48 163.6 7.1 1.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KXS13181.1 - 2.5e-06 26.8 0.3 3.9e-06 26.2 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KXS13181.1 - 7.6e-06 25.3 0.5 2.4e-05 23.7 0.1 1.8 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 KXS13181.1 - 0.0008 19.6 0.1 0.0022 18.2 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXS13181.1 - 0.0025 17.1 0.0 0.011 14.9 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXS13181.1 - 0.0029 18.1 1.6 0.034 14.7 0.0 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KXS13181.1 - 0.068 12.0 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase RRM_1 PF00076.22 KXS13182.1 - 2e-44 149.3 0.0 9.3e-18 63.8 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KXS13182.1 - 1.5e-05 24.7 0.0 3.6e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Occluded RNA-recognition motif RRM_5 PF13893.6 KXS13182.1 - 2.2e-05 24.0 0.0 0.00039 20.0 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KXS13182.1 - 0.00013 22.0 0.0 0.047 13.8 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 KXS13182.1 - 0.00031 20.7 0.0 0.0026 17.7 0.0 2.4 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 KXS13182.1 - 0.0012 18.8 0.0 0.0037 17.3 0.0 1.7 2 0 0 2 2 2 1 RNA binding motif Limkain-b1 PF11608.8 KXS13182.1 - 0.16 12.0 0.0 6.3 6.9 0.0 2.5 2 0 0 2 2 2 0 Limkain b1 Pex16 PF08610.10 KXS13183.1 - 1.2e-46 159.3 0.3 6.1e-46 157.1 0.3 2.0 1 1 0 1 1 1 1 Peroxisomal membrane protein (Pex16) Annexin PF00191.20 KXS13184.1 - 3.4e-61 203.2 0.3 3.9e-19 68.5 0.2 4.2 4 0 0 4 4 4 4 Annexin RHD3 PF05879.12 KXS13184.1 - 0.078 11.1 0.2 0.093 10.9 0.2 1.2 1 0 0 1 1 1 0 Root hair defective 3 GTP-binding protein (RHD3) Pkinase_Tyr PF07714.17 KXS13185.1 - 1.6e-35 122.7 0.0 2e-35 122.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXS13185.1 - 6.1e-31 107.7 0.0 7.8e-31 107.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KXS13185.1 - 0.0005 19.5 0.0 0.00073 18.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KXS13185.1 - 0.0012 18.3 0.0 0.0015 17.9 0.0 1.1 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KXS13185.1 - 0.0046 16.6 0.0 0.0083 15.7 0.0 1.5 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 KXS13185.1 - 0.041 13.8 0.0 0.077 12.9 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KXS13185.1 - 0.12 11.3 0.0 0.18 10.7 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Inhibitor_I9 PF05922.16 KXS13186.1 - 1e-10 42.1 0.1 2.6e-10 40.8 0.1 1.6 1 1 0 1 1 1 1 Peptidase inhibitor I9 Sigma_reg_C PF13791.6 KXS13186.1 - 0.014 15.6 0.0 0.015 15.5 0.0 1.0 1 0 0 1 1 1 0 Sigma factor regulator C-terminal DAHP_snth_FXD PF18152.1 KXS13186.1 - 0.033 14.0 0.0 0.05 13.4 0.0 1.3 1 0 0 1 1 1 0 DAHP synthase ferredoxin-like domain CspB_prodomain PF18425.1 KXS13186.1 - 0.039 13.9 0.0 0.045 13.8 0.0 1.1 1 0 0 1 1 1 0 Csp protease B prodomain IES5 PF17335.2 KXS13186.1 - 0.11 12.7 0.0 0.13 12.6 0.0 1.2 1 0 0 1 1 1 0 Ino80 complex subunit 5 CWC25 PF12542.8 KXS13187.1 - 2.3e-23 83.0 1.3 2.3e-23 83.0 1.3 2.7 3 0 0 3 3 3 1 Pre-mRNA splicing factor Cir_N PF10197.9 KXS13187.1 - 1.7e-13 50.5 9.6 1.7e-13 50.5 9.6 4.6 3 2 1 4 4 4 1 N-terminal domain of CBF1 interacting co-repressor CIR DSPc PF00782.20 KXS13188.1 - 4.9e-31 107.3 0.0 6.5e-31 106.9 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 KXS13188.1 - 0.076 13.3 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 Rit1 DUSP-like domain DUF4224 PF13986.6 KXS13188.1 - 0.17 11.8 0.0 0.55 10.2 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4224) bZIP_1 PF00170.21 KXS13189.1 - 2e-08 34.2 7.3 4.1e-08 33.2 7.3 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KXS13189.1 - 0.00029 20.9 8.4 0.00049 20.1 8.4 1.3 1 0 0 1 1 1 1 Basic region leucine zipper PAP1 PF08601.10 KXS13189.1 - 0.0035 17.1 0.1 0.0035 17.1 0.1 2.5 2 1 0 2 2 2 1 Transcription factor PAP1 GvpL_GvpF PF06386.11 KXS13189.1 - 0.043 13.7 1.9 0.065 13.2 1.9 1.3 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Tom6 PF17112.5 KXS13191.1 - 0.11 12.0 0.0 0.31 10.6 0.0 1.7 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom6, fungal AA_permease_2 PF13520.6 KXS13191.1 - 0.11 11.3 24.0 0.035 12.9 15.9 2.2 1 1 1 2 2 2 0 Amino acid permease MIR PF02815.19 KXS13192.1 - 1.1e-11 44.9 0.1 6.2e-10 39.2 0.1 2.6 1 1 2 3 3 3 3 MIR domain Metallophos_2 PF12850.7 KXS13195.1 - 4.1e-18 66.1 0.1 5.3e-18 65.7 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 KXS13195.1 - 0.0027 18.2 0.1 2.1 8.8 0.0 2.3 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase CMD PF02627.20 KXS13196.1 - 6.8e-18 64.5 0.1 9e-18 64.1 0.1 1.2 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family PhyH PF05721.13 KXS13197.1 - 3.2e-26 92.9 0.0 4.8e-26 92.3 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Sarcoglycan_2 PF05510.13 KXS13198.1 - 0.077 11.8 0.1 0.2 10.4 0.0 1.6 2 0 0 2 2 2 0 Sarcoglycan alpha/epsilon ABC_membrane PF00664.23 KXS13200.1 - 3e-118 394.4 22.3 9.9e-65 218.9 4.1 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KXS13200.1 - 2.6e-64 215.9 0.0 1.7e-33 116.0 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KXS13200.1 - 3.2e-15 56.2 2.2 6.7e-05 22.4 0.0 4.3 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KXS13200.1 - 4.7e-09 36.6 0.0 0.0041 17.4 0.0 3.8 3 1 0 3 3 3 2 AAA domain AAA_16 PF13191.6 KXS13200.1 - 7.3e-09 36.2 1.9 0.0031 17.9 0.0 3.4 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 KXS13200.1 - 1.2e-06 28.1 3.0 0.009 15.7 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_ATPase PF09818.9 KXS13200.1 - 1.7e-06 27.1 1.1 0.018 13.9 0.1 3.6 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_21 PF13304.6 KXS13200.1 - 4.1e-06 26.8 0.2 0.069 13.0 0.0 3.6 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KXS13200.1 - 1.8e-05 24.7 0.1 0.042 13.8 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_18 PF13238.6 KXS13200.1 - 2.6e-05 24.8 0.0 0.1 13.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 KXS13200.1 - 8.2e-05 22.9 0.2 2 8.6 0.1 3.5 2 1 1 3 3 3 1 AAA domain AAA PF00004.29 KXS13200.1 - 9.5e-05 22.8 3.4 0.65 10.4 0.3 4.1 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KXS13200.1 - 0.0001 22.1 0.0 0.21 11.3 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_30 PF13604.6 KXS13200.1 - 0.00013 21.8 3.3 0.13 11.9 0.1 3.4 2 2 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 KXS13200.1 - 0.00013 21.3 0.8 0.051 12.8 0.0 2.9 3 0 0 3 3 3 1 Zeta toxin AAA_15 PF13175.6 KXS13200.1 - 0.00021 21.1 0.0 0.32 10.7 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain G-alpha PF00503.20 KXS13200.1 - 0.00022 20.5 0.0 0.1 11.7 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit DUF87 PF01935.17 KXS13200.1 - 0.00024 21.3 0.5 0.67 10.0 0.0 2.6 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_33 PF13671.6 KXS13200.1 - 0.00025 21.2 0.0 0.42 10.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 KXS13200.1 - 0.00052 20.2 5.3 0.54 10.5 0.6 3.9 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.14 KXS13200.1 - 0.0016 18.4 0.1 5.1 7.1 0.0 3.4 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) PRK PF00485.18 KXS13200.1 - 0.0017 18.1 0.0 1.9 8.2 0.0 2.4 2 0 0 2 2 2 2 Phosphoribulokinase / Uridine kinase family Ploopntkinase3 PF18751.1 KXS13200.1 - 0.0024 17.8 0.3 0.35 10.8 0.0 3.1 2 1 0 2 2 2 1 P-loop Nucleotide Kinase3 AAA_25 PF13481.6 KXS13200.1 - 0.0031 17.1 0.1 2.6 7.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain Cytidylate_kin PF02224.18 KXS13200.1 - 0.0032 17.2 0.0 1.3 8.7 0.0 2.5 2 0 0 2 2 2 1 Cytidylate kinase APS_kinase PF01583.20 KXS13200.1 - 0.0047 16.8 0.0 1.1 9.1 0.0 2.7 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_7 PF12775.7 KXS13200.1 - 0.0056 16.2 0.0 1.8 8.0 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region MMR_HSR1 PF01926.23 KXS13200.1 - 0.0094 16.0 1.8 1.5 8.9 0.0 3.4 4 0 0 4 4 2 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 KXS13200.1 - 0.012 16.0 0.1 15 6.0 0.0 3.3 3 0 0 3 3 3 0 RNA helicase NB-ARC PF00931.22 KXS13200.1 - 0.014 14.6 0.2 2.3 7.3 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain AAA_23 PF13476.6 KXS13200.1 - 0.027 15.0 0.3 0.73 10.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 KXS13200.1 - 0.029 14.1 0.4 7.1 6.3 0.0 3.6 4 0 0 4 4 4 0 IstB-like ATP binding protein ATP_bind_1 PF03029.17 KXS13200.1 - 0.045 13.5 0.1 1.9 8.2 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein KAP_NTPase PF07693.14 KXS13200.1 - 0.065 12.5 0.0 4 6.6 0.0 2.3 2 0 0 2 2 2 0 KAP family P-loop domain Rad17 PF03215.15 KXS13200.1 - 0.086 12.7 0.0 1 9.3 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain DUF1778 PF08681.11 KXS13200.1 - 0.12 12.4 0.0 0.58 10.1 0.0 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1778) NACHT PF05729.12 KXS13200.1 - 0.16 11.8 0.2 7 6.5 0.0 2.6 2 0 0 2 2 2 0 NACHT domain dNK PF01712.19 KXS13200.1 - 0.19 11.6 0.0 3.6 7.4 0.0 2.2 2 0 0 2 2 2 0 Deoxynucleoside kinase Ifi-6-16 PF06140.13 KXS13200.1 - 0.58 10.1 7.6 0.28 11.1 3.3 2.8 2 0 0 2 2 1 0 Interferon-induced 6-16 family WD40 PF00400.32 KXS13201.1 - 1.9e-23 82.3 15.9 6.7e-05 23.6 0.2 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.8 KXS13201.1 - 0.00059 18.6 4.0 0.0045 15.7 0.4 2.8 1 1 1 3 3 3 2 Nucleoporin Nup120/160 zf-LITAF-like PF10601.9 KXS13202.1 - 3.2e-12 46.5 11.9 4.5e-12 46.1 11.9 1.2 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain UPF0193 PF05250.11 KXS13203.1 - 3.3e-12 46.7 1.3 8.8e-11 42.0 1.3 2.2 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0193) Cas_APE2256 PF09651.10 KXS13204.1 - 0.19 11.6 0.2 0.29 11.0 0.2 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_APE2256) CPSF100_C PF13299.6 KXS13204.1 - 0.21 11.7 4.4 2.7 8.1 4.9 2.1 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Borrelia_P83 PF05262.11 KXS13204.1 - 4.4 5.7 10.0 5.8 5.3 10.0 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Pkinase PF00069.25 KXS13205.1 - 1.9e-33 115.9 0.0 2.8e-24 85.9 0.0 3.8 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 KXS13205.1 - 1.6e-11 44.0 0.0 8.8e-05 21.9 0.0 3.9 3 1 0 3 3 3 3 Protein tyrosine kinase Kinase-like PF14531.6 KXS13205.1 - 1.2e-07 31.4 0.0 9.6e-05 21.8 0.0 2.1 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 KXS13205.1 - 0.038 13.4 0.0 0.066 12.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DcuA_DcuB PF03605.14 KXS13205.1 - 0.32 9.8 0.4 0.52 9.1 0.4 1.2 1 0 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter Roughex PF06020.11 KXS13206.1 - 0.26 10.3 2.8 0.43 9.6 2.7 1.4 1 1 1 2 2 2 0 Drosophila roughex protein MgtE PF01769.16 KXS13207.1 - 1.3e-12 48.2 1.5 2.2e-12 47.5 1.5 1.3 1 0 0 1 1 1 1 Divalent cation transporter ACT_7 PF13840.6 KXS13208.1 - 2e-27 94.7 0.0 2.4e-13 49.7 0.0 2.6 2 0 0 2 2 2 2 ACT domain Castor1_N PF18700.1 KXS13208.1 - 1.7e-11 43.8 0.0 2.2e-05 24.2 0.0 2.4 2 0 0 2 2 2 2 Cytosolic arginine sensor for mTORC1 subunit 1 N-terminal domain Ndc1_Nup PF09531.10 KXS13209.1 - 3.7 6.1 5.8 4.3 5.9 5.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PBP1_TM PF14812.6 KXS13209.1 - 7.4 7.0 8.2 4.5 7.7 2.2 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Glyco_hydro_10 PF00331.20 KXS13210.1 - 1e-78 264.7 0.1 1.6e-78 264.1 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 BTB PF00651.31 KXS13211.1 - 1.3e-06 28.6 0.0 1.6e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain HTH_23 PF13384.6 KXS13212.1 - 0.16 11.8 0.0 0.37 10.7 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 KXS13212.1 - 0.19 11.9 0.0 0.41 10.8 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain RNase_T PF00929.24 KXS13213.1 - 1.6e-35 123.1 0.0 1.9e-35 122.9 0.0 1.0 1 0 0 1 1 1 1 Exonuclease DUF5051 PF16473.5 KXS13213.1 - 0.011 15.7 0.0 0.016 15.2 0.0 1.3 1 0 0 1 1 1 0 3' exoribonuclease, RNase T-like LexA_DNA_bind PF01726.16 KXS13213.1 - 0.093 12.5 0.0 0.24 11.2 0.0 1.7 1 0 0 1 1 1 0 LexA DNA binding domain Peptidase_M18 PF02127.15 KXS13214.1 - 1.5e-155 518.3 0.0 1.7e-155 518.1 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 KXS13214.1 - 4.6e-05 22.6 0.0 8.8e-05 21.7 0.0 1.4 1 0 0 1 1 1 1 M42 glutamyl aminopeptidase Gln-synt_C PF00120.24 KXS13215.1 - 2.9e-88 296.2 0.0 4.5e-88 295.5 0.0 1.2 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N_2 PF16952.5 KXS13215.1 - 2.5e-05 24.0 0.0 4.8e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase N-terminal domain LHC PF00556.20 KXS13216.1 - 0.18 12.0 0.9 0.28 11.4 0.9 1.3 1 0 0 1 1 1 0 Antenna complex alpha/beta subunit Aa_trans PF01490.18 KXS13217.1 - 3.3e-29 101.8 13.4 8e-29 100.6 13.4 1.5 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein DUF4436 PF14494.6 KXS13218.1 - 0.18 11.1 0.1 0.28 10.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4436) Nop14 PF04147.12 KXS13218.1 - 7.4 4.7 10.0 9.9 4.2 10.0 1.1 1 0 0 1 1 1 0 Nop14-like family TPR_2 PF07719.17 KXS13219.1 - 0.0002 21.2 0.0 0.42 10.9 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat zf-HC3 PF16827.5 KXS13220.1 - 0.18 12.0 3.7 4.7 7.5 0.2 2.5 1 1 1 2 2 2 0 zinc-finger MFS_1 PF07690.16 KXS13224.1 - 6.4e-47 160.2 43.8 6.4e-47 160.2 43.8 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KXS13224.1 - 7.5e-13 47.8 20.7 1.1e-12 47.2 20.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KXS13224.1 - 2.4e-11 43.2 11.1 2.4e-11 43.2 11.1 3.6 3 2 0 3 3 3 1 Sugar (and other) transporter HlyIII PF03006.20 KXS13224.1 - 1.5 8.4 15.3 0.013 15.2 4.7 2.7 2 1 1 3 3 3 0 Haemolysin-III related Thioredoxin PF00085.20 KXS13225.1 - 1.6e-24 85.9 0.1 1.9e-24 85.6 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 KXS13225.1 - 1.1e-05 25.6 0.0 0.00023 21.4 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_2 PF13098.6 KXS13225.1 - 0.0018 18.7 0.1 0.0098 16.3 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.10 KXS13225.1 - 0.0026 17.5 0.0 0.01 15.6 0.0 1.8 1 1 0 1 1 1 1 Redoxin Thioredoxin_9 PF14595.6 KXS13225.1 - 0.012 15.3 0.0 0.013 15.3 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin AhpC-TSA PF00578.21 KXS13225.1 - 0.013 15.4 0.1 0.026 14.4 0.1 1.5 1 1 0 1 1 1 0 AhpC/TSA family TraF PF13728.6 KXS13225.1 - 0.02 14.8 0.0 0.025 14.4 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein Mcp5_PH PF12814.7 KXS13226.1 - 2.2e-05 24.5 0.0 9e-05 22.6 0.0 1.8 1 1 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology LPD23 PF18838.1 KXS13226.1 - 0.055 13.2 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Large polyvalent protein associated domain 23 CENP-F_leu_zip PF10473.9 KXS13227.1 - 0.00016 21.7 7.0 0.00016 21.7 7.0 14.4 6 3 7 14 14 14 5 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Rab5-bind PF09311.11 KXS13227.1 - 0.00017 21.1 13.0 0.00017 21.1 13.0 10.2 4 2 3 9 9 9 4 Rabaptin-like protein 3HCDH_RFF PF18321.1 KXS13227.1 - 0.22 12.0 4.4 1.6 9.3 4.4 2.6 1 0 0 1 1 1 0 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain TFA2_Winged_2 PF18121.1 KXS13227.1 - 4.3 7.1 6.5 40 4.0 0.1 4.0 3 0 0 3 3 3 0 TFA2 Winged helix domain 2 Dimer_Tnp_hAT PF05699.14 KXS13229.1 - 1e-20 73.3 0.0 1.2e-20 73.1 0.0 1.1 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF3326 PF11805.8 KXS13230.1 - 0.15 10.9 0.0 0.24 10.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3326) Cyt-b5 PF00173.28 KXS13232.1 - 0.027 14.6 0.0 0.053 13.7 0.0 1.3 1 0 0 1 1 1 0 Cytochrome b5-like Heme/Steroid binding domain Fzo_mitofusin PF04799.13 KXS13232.1 - 0.17 11.4 0.2 0.28 10.7 0.2 1.3 1 0 0 1 1 1 0 fzo-like conserved region Inositol_P PF00459.25 KXS13233.1 - 6.2e-55 186.6 0.3 2.7e-54 184.5 0.3 1.8 1 1 0 1 1 1 1 Inositol monophosphatase family Chs7 PF12271.8 KXS13234.1 - 6e-105 350.7 22.4 7e-105 350.5 22.4 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone Na_Ca_ex PF01699.24 KXS13239.1 - 4e-44 150.2 35.4 3e-22 79.2 6.9 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein 7tm_7 PF08395.12 KXS13239.1 - 0.0056 15.9 0.2 0.0056 15.9 0.2 1.8 2 0 0 2 2 2 1 7tm Chemosensory receptor YWFCY PF14293.6 KXS13239.1 - 0.011 16.0 0.0 0.053 13.8 0.0 2.2 2 0 0 2 2 2 0 YWFCY protein DUF1240 PF06836.12 KXS13239.1 - 0.094 13.3 0.1 0.094 13.3 0.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1240) GXWXG PF14231.6 KXS13240.1 - 0.11 12.7 0.8 0.4 10.8 0.8 2.0 1 1 0 1 1 1 0 GXWXG protein Na_sulph_symp PF00939.19 KXS13241.1 - 2.5e-32 112.5 33.1 3.7e-32 112.0 33.1 1.2 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region SPX PF03105.19 KXS13241.1 - 1e-29 104.7 25.2 1.6e-13 51.4 0.1 3.9 1 1 1 2 2 2 2 SPX domain CitMHS PF03600.16 KXS13241.1 - 1e-26 93.8 33.9 1e-26 93.8 33.9 2.2 1 1 1 2 2 2 1 Citrate transporter Myotub-related PF06602.14 KXS13242.1 - 5.8e-73 245.8 0.0 1.8e-70 237.7 0.0 2.1 2 0 0 2 2 2 2 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.6 KXS13242.1 - 0.085 12.8 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family Nop10p PF04135.12 KXS13243.1 - 6.3e-25 87.0 2.0 7.3e-25 86.8 2.0 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family Pkinase_Tyr PF07714.17 KXS13244.1 - 3.2e-07 29.9 0.0 0.0021 17.4 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXS13244.1 - 1.5e-05 24.5 0.0 2.2e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain HSP9_HSP12 PF04119.12 KXS13246.1 - 1.5e-18 66.9 1.9 1.5e-18 66.9 1.9 2.1 1 1 0 2 2 2 1 Heat shock protein 9/12 CTU2 PF10288.9 KXS13247.1 - 2.1e-07 31.2 0.0 5.3e-07 29.9 0.0 1.7 1 0 0 1 1 1 1 Cytoplasmic tRNA 2-thiolation protein 2 Methyltransf_31 PF13847.6 KXS13248.1 - 5.3e-20 71.7 0.0 7.4e-20 71.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXS13248.1 - 6.7e-13 49.2 0.0 1.2e-12 48.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXS13248.1 - 1.1e-12 48.6 0.0 1.7e-12 48.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXS13248.1 - 6.3e-12 46.0 0.0 1.1e-11 45.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXS13248.1 - 4.1e-11 43.0 0.0 6.9e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXS13248.1 - 4.7e-06 26.3 0.0 7.7e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 KXS13248.1 - 6.6e-06 25.7 0.0 1.1e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Ubie_methyltran PF01209.18 KXS13248.1 - 8.3e-06 25.3 0.0 1.4e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.13 KXS13248.1 - 1.8e-05 24.3 0.0 2.7e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_9 PF08003.11 KXS13248.1 - 0.0022 17.0 0.0 0.0031 16.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) CMAS PF02353.20 KXS13248.1 - 0.018 14.4 0.0 0.041 13.2 0.0 1.5 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.18 KXS13248.1 - 0.022 14.0 0.0 0.046 13.0 0.0 1.5 1 0 0 1 1 1 0 O-methyltransferase domain HTH_9 PF08221.11 KXS13248.1 - 0.037 14.1 0.0 0.074 13.2 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 helix-turn-helix domain Cullin PF00888.22 KXS13248.1 - 0.093 11.3 0.0 0.13 10.9 0.0 1.1 1 0 0 1 1 1 0 Cullin family PCMT PF01135.19 KXS13248.1 - 0.099 12.4 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.7 KXS13248.1 - 0.11 12.5 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Pkinase_Tyr PF07714.17 KXS13249.1 - 2.2e-54 184.5 0.0 2.2e-27 96.0 0.0 3.1 3 0 0 3 3 3 3 Protein tyrosine kinase Pkinase PF00069.25 KXS13249.1 - 2.8e-45 154.7 0.0 3.4e-24 85.6 0.0 3.1 3 0 0 3 3 3 3 Protein kinase domain Kinase-like PF14531.6 KXS13249.1 - 0.0007 19.0 0.0 0.017 14.4 0.0 2.3 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KXS13249.1 - 0.0058 16.0 0.0 1.8 7.8 0.0 2.4 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family EamA PF00892.20 KXS13252.1 - 2.8e-22 79.4 23.9 2.2e-12 47.3 8.6 3.1 2 1 1 3 3 3 3 EamA-like transporter family UPF0060 PF02694.15 KXS13252.1 - 0.016 15.4 1.5 0.029 14.6 0.5 1.9 2 0 0 2 2 2 0 Uncharacterised BCR, YnfA/UPF0060 family SUR7 PF06687.12 KXS13252.1 - 0.03 13.9 1.2 1 9.0 0.0 2.9 3 0 0 3 3 3 0 SUR7/PalI family IMS PF00817.20 KXS13253.1 - 7e-20 71.6 0.0 5e-13 49.3 0.0 2.4 2 0 0 2 2 2 2 impB/mucB/samB family Mem_trans PF03547.18 KXS13254.1 - 5.2e-21 74.5 0.1 8.1e-21 73.9 0.1 1.3 1 0 0 1 1 1 1 Membrane transport protein LapA_dom PF06305.11 KXS13254.1 - 0.037 13.8 0.9 0.037 13.8 0.9 3.4 4 0 0 4 4 4 0 Lipopolysaccharide assembly protein A domain Mif2_N PF15624.6 KXS13254.1 - 0.97 10.1 4.7 1.5 9.5 4.7 1.2 1 0 0 1 1 1 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Mem_trans PF03547.18 KXS13255.1 - 1.4e-16 59.9 6.4 3.2e-15 55.4 6.4 2.3 1 1 0 1 1 1 1 Membrane transport protein LapA_dom PF06305.11 KXS13255.1 - 0.029 14.2 0.4 0.029 14.2 0.4 2.5 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain DUF5426 PF17473.2 KXS13255.1 - 0.27 11.5 0.6 0.51 10.6 0.6 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5426) HSP9_HSP12 PF04119.12 KXS13256.1 - 1.3e-08 35.1 0.3 3.2e-08 33.8 0.3 1.6 1 1 1 2 2 2 1 Heat shock protein 9/12 HSP9_HSP12 PF04119.12 KXS13257.1 - 1.1e-28 99.4 12.3 3.6e-21 75.3 3.1 2.5 1 1 2 3 3 3 2 Heat shock protein 9/12 Dehydrin PF00257.19 KXS13257.1 - 0.0051 17.4 0.3 0.0071 16.9 0.3 1.2 1 0 0 1 1 1 1 Dehydrin Ig_J_chain PF15097.6 KXS13257.1 - 0.011 15.6 0.1 0.015 15.2 0.1 1.2 1 0 0 1 1 1 0 Immunoglobulin J chain SpoIISA_toxin PF14171.6 KXS13257.1 - 0.24 11.1 0.1 0.25 11.0 0.1 1.1 1 0 0 1 1 1 0 Toxin SpoIISA, type II toxin-antitoxin system YtxH PF12732.7 KXS13257.1 - 1.5 9.4 4.9 59 4.3 4.9 2.1 1 1 0 1 1 1 0 YtxH-like protein CitMHS_2 PF16980.5 KXS13258.1 - 1.3e-150 501.9 17.5 1.8e-81 274.1 9.6 2.0 2 0 0 2 2 2 2 Putative citrate transport CitMHS PF03600.16 KXS13258.1 - 9.5e-18 64.4 1.4 5.6e-16 58.6 0.0 2.5 1 1 1 2 2 2 2 Citrate transporter Med13_N PF11597.8 KXS13259.1 - 0.0062 16.0 0.4 0.0083 15.6 0.4 1.1 1 0 0 1 1 1 1 Mediator complex subunit 13 N-terminal Peptidase_M13 PF01431.21 KXS13259.1 - 0.026 14.1 0.6 0.037 13.6 0.6 1.2 1 0 0 1 1 1 0 Peptidase family M13 HSP9_HSP12 PF04119.12 KXS13260.1 - 7.3e-29 100.0 10.1 1.5e-21 76.5 2.3 2.1 1 1 2 3 3 3 2 Heat shock protein 9/12 Grg1 PF11034.8 KXS13260.1 - 0.03 14.5 1.8 0.067 13.4 1.0 2.0 1 1 1 2 2 2 0 Glucose-repressible protein Grg1 NAD_kinase PF01513.21 KXS13261.1 - 3.2e-45 154.6 0.0 3.9e-45 154.3 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 KXS13261.1 - 0.01 15.5 0.1 0.027 14.1 0.0 1.7 2 0 0 2 2 2 1 Diacylglycerol kinase catalytic domain ECH_1 PF00378.20 KXS13262.1 - 8.5e-44 149.7 0.0 2.2e-43 148.4 0.0 1.6 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXS13262.1 - 1.5e-23 83.9 0.0 1.2e-22 80.8 0.0 1.8 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase PDZ_1 PF12812.7 KXS13263.1 - 1.5e-41 140.3 0.0 6.1e-28 96.7 0.0 2.6 2 0 0 2 2 2 2 PDZ-like domain Trypsin_2 PF13365.6 KXS13263.1 - 1.2e-23 84.6 1.0 8.3e-20 72.2 0.0 2.5 2 0 0 2 2 2 2 Trypsin-like peptidase domain PDZ_6 PF17820.1 KXS13263.1 - 2.3e-20 72.2 0.1 1.5e-07 31.1 0.1 4.6 4 0 0 4 4 4 3 PDZ domain PDZ_2 PF13180.6 KXS13263.1 - 1.9e-15 56.9 1.0 6.5e-07 29.6 0.1 4.6 4 0 0 4 4 4 3 PDZ domain PDZ PF00595.24 KXS13263.1 - 8.8e-11 42.0 0.0 0.00022 21.5 0.0 4.1 4 0 0 4 4 4 2 PDZ domain Tricorn_PDZ PF14685.6 KXS13263.1 - 0.0002 21.3 2.3 0.0083 16.1 0.2 3.8 5 0 0 5 5 5 1 Tricorn protease PDZ domain PDZ_3 PF17815.1 KXS13263.1 - 0.0083 16.0 0.0 1.6 8.5 0.0 3.2 3 1 0 3 3 3 1 PDZ domain Peptidase_S46 PF10459.9 KXS13263.1 - 0.1 11.2 0.1 0.18 10.4 0.1 1.3 1 0 0 1 1 1 0 Peptidase S46 DUF4889 PF16230.5 KXS13263.1 - 0.16 12.2 0.4 0.39 11.0 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4889) DUF31 PF01732.16 KXS13263.1 - 0.19 11.2 0.2 0.28 10.7 0.2 1.2 1 0 0 1 1 1 0 Putative peptidase (DUF31) TRAPP PF04051.16 KXS13264.1 - 1.4e-34 118.9 0.0 1.7e-34 118.6 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Ins134_P3_kin PF05770.11 KXS13264.1 - 0.1 12.1 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain C_GCAxxG_C_C PF09719.10 KXS13264.1 - 0.12 12.6 0.0 18 5.6 0.0 2.2 2 0 0 2 2 2 0 Putative redox-active protein (C_GCAxxG_C_C) Enkurin PF13864.6 KXS13265.1 - 2.9e-23 82.1 1.9 4.5e-23 81.5 1.9 1.3 1 0 0 1 1 1 1 Calmodulin-binding CRAL_TRIO PF00650.20 KXS13266.1 - 1.7e-30 105.8 0.0 2.6e-30 105.2 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KXS13266.1 - 1.1e-07 32.0 0.2 1.7e-07 31.3 0.2 1.4 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KXS13266.1 - 2.6e-05 24.4 0.0 3.2e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DUF4336 PF14234.6 KXS13267.1 - 4.8e-13 49.0 0.2 4.6e-09 35.9 0.0 2.9 1 1 1 2 2 2 2 Domain of unknown function (DUF4336) LSDAT_euk PF18139.1 KXS13268.1 - 0.047 13.1 0.2 0.053 12.9 0.2 1.1 1 0 0 1 1 1 0 SLOG in TRPM AAA PF00004.29 KXS13269.1 - 3.2e-96 318.8 0.0 4.3e-47 159.9 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KXS13269.1 - 3.8e-25 87.4 4.6 1.9e-12 46.8 0.2 3.1 2 2 0 2 2 2 2 AAA+ lid domain CDC48_N PF02359.18 KXS13269.1 - 7.4e-19 67.7 1.7 2.1e-18 66.2 1.7 1.9 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 KXS13269.1 - 9.7e-14 51.4 0.0 2.6e-05 24.0 0.0 3.1 2 2 1 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 KXS13269.1 - 3.6e-12 46.7 0.0 1.1e-06 28.9 0.0 3.2 3 1 0 3 3 3 2 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 KXS13269.1 - 6.8e-12 45.6 0.1 8.7e-06 25.8 0.1 3.7 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KXS13269.1 - 7.4e-12 46.0 0.0 0.00084 19.8 0.0 4.3 2 2 0 2 2 2 2 AAA ATPase domain AAA_33 PF13671.6 KXS13269.1 - 3.3e-11 43.5 0.0 2.6e-05 24.4 0.0 3.0 3 0 0 3 3 2 2 AAA domain CDC48_2 PF02933.17 KXS13269.1 - 3.5e-10 39.5 0.1 1.2e-09 37.8 0.0 1.9 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), domain 2 AAA_22 PF13401.6 KXS13269.1 - 2.4e-09 37.6 0.2 0.028 14.7 0.0 4.0 2 2 1 3 3 3 2 AAA domain TIP49 PF06068.13 KXS13269.1 - 2.4e-08 33.6 0.0 0.0025 17.1 0.0 2.7 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_18 PF13238.6 KXS13269.1 - 1.1e-07 32.4 0.1 0.031 14.8 0.0 3.2 3 0 0 3 3 2 2 AAA domain RNA_helicase PF00910.22 KXS13269.1 - 3.4e-07 30.6 0.0 0.0058 17.0 0.0 3.0 3 0 0 3 3 2 2 RNA helicase AAA_14 PF13173.6 KXS13269.1 - 3.7e-07 30.3 0.0 0.011 15.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 KXS13269.1 - 6.5e-07 28.9 0.1 0.024 14.0 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 KXS13269.1 - 6.8e-07 29.1 1.3 1.2 8.7 0.0 4.3 3 1 0 4 4 4 2 AAA domain IstB_IS21 PF01695.17 KXS13269.1 - 2.1e-06 27.6 0.0 0.073 12.8 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein ABC_tran PF00005.27 KXS13269.1 - 2.1e-06 28.3 0.0 0.0099 16.4 0.0 3.5 2 1 0 2 2 2 1 ABC transporter Vps4_C PF09336.10 KXS13269.1 - 2.3e-06 27.5 0.9 4.8e-05 23.3 0.1 3.0 3 0 0 3 3 2 1 Vps4 C terminal oligomerisation domain AAA_7 PF12775.7 KXS13269.1 - 9.3e-06 25.3 0.0 0.11 12.0 0.0 2.7 2 1 0 2 2 2 2 P-loop containing dynein motor region ATPase PF06745.13 KXS13269.1 - 1.3e-05 24.6 0.1 1 8.7 0.0 3.5 3 0 0 3 3 3 2 KaiC AAA_28 PF13521.6 KXS13269.1 - 1.4e-05 25.4 0.0 0.17 12.2 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_17 PF13207.6 KXS13269.1 - 2.7e-05 24.6 0.7 0.76 10.2 0.0 3.8 4 0 0 4 4 3 2 AAA domain Parvo_NS1 PF01057.17 KXS13269.1 - 5e-05 22.5 0.1 0.035 13.2 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_24 PF13479.6 KXS13269.1 - 5.4e-05 23.0 0.0 0.16 11.7 0.0 2.9 3 0 0 3 3 2 2 AAA domain Bac_DnaA PF00308.18 KXS13269.1 - 5.6e-05 23.1 0.0 0.66 9.8 0.0 3.0 3 0 0 3 3 3 2 Bacterial dnaA protein Viral_helicase1 PF01443.18 KXS13269.1 - 9.1e-05 22.3 0.0 0.0074 16.1 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase ATPase_2 PF01637.18 KXS13269.1 - 0.00012 22.1 0.1 0.22 11.4 0.0 3.3 2 1 0 2 2 2 1 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 KXS13269.1 - 0.00016 21.4 0.0 1 9.0 0.0 3.1 2 1 0 2 2 2 2 Sigma-54 interaction domain TsaE PF02367.17 KXS13269.1 - 0.00022 21.2 0.0 0.32 11.0 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 KXS13269.1 - 0.00031 20.0 0.0 0.042 13.0 0.0 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF815) NB-ARC PF00931.22 KXS13269.1 - 0.00043 19.5 0.0 0.17 11.0 0.0 2.6 2 0 0 2 2 2 1 NB-ARC domain NACHT PF05729.12 KXS13269.1 - 0.00058 19.8 0.1 0.23 11.4 0.0 2.8 3 0 0 3 3 2 1 NACHT domain ResIII PF04851.15 KXS13269.1 - 0.00067 19.7 0.0 0.12 12.4 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_3 PF07726.11 KXS13269.1 - 0.00077 19.3 0.0 1.7 8.5 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 KXS13269.1 - 0.0013 18.3 0.7 1.7 8.0 0.0 2.7 3 0 0 3 3 2 2 PhoH-like protein Zeta_toxin PF06414.12 KXS13269.1 - 0.0014 17.9 0.0 0.68 9.2 0.0 2.8 2 0 0 2 2 2 1 Zeta toxin DUF2075 PF09848.9 KXS13269.1 - 0.002 17.4 0.0 0.94 8.6 0.0 2.5 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 KXS13269.1 - 0.0021 18.4 0.4 3.9 7.8 0.1 3.8 3 1 0 4 4 3 0 AAA domain Rad17 PF03215.15 KXS13269.1 - 0.004 17.1 0.0 0.68 9.8 0.0 2.7 2 0 0 2 2 2 1 Rad17 P-loop domain Sigma54_activ_2 PF14532.6 KXS13269.1 - 0.0053 16.9 0.0 3.9 7.6 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_11 PF13086.6 KXS13269.1 - 0.0089 15.8 0.2 5.5 6.7 0.0 2.6 3 0 0 3 3 2 0 AAA domain Cytidylate_kin2 PF13189.6 KXS13269.1 - 0.016 15.3 0.0 1.4 9.0 0.0 2.8 2 0 0 2 2 2 0 Cytidylate kinase-like family NTPase_1 PF03266.15 KXS13269.1 - 0.018 14.9 3.6 5 7.0 0.0 4.5 4 1 0 5 5 4 0 NTPase Molydop_binding PF01568.21 KXS13269.1 - 0.033 14.2 0.2 0.095 12.7 0.2 1.8 1 0 0 1 1 1 0 Molydopterin dinucleotide binding domain AAA_30 PF13604.6 KXS13269.1 - 0.038 13.7 0.1 8.2 6.1 0.1 2.7 2 0 0 2 2 2 0 AAA domain Cytidylate_kin PF02224.18 KXS13269.1 - 0.059 13.1 0.1 19 4.9 0.0 3.1 3 0 0 3 3 2 0 Cytidylate kinase SKI PF01202.22 KXS13269.1 - 0.1 12.7 0.1 9.5 6.3 0.0 2.6 2 0 0 2 2 2 0 Shikimate kinase PduV-EutP PF10662.9 KXS13269.1 - 0.17 11.6 0.0 5.7 6.7 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Hydin_ADK PF17213.3 KXS13269.1 - 0.28 11.4 1.7 1.6e+02 2.4 0.0 3.9 4 0 0 4 4 4 0 Hydin Adenylate kinase-like domain ATP11 PF06644.11 KXS13270.1 - 4.1e-59 200.6 0.0 5.2e-59 200.3 0.0 1.1 1 0 0 1 1 1 1 ATP11 protein HAD_SAK_1 PF10307.9 KXS13271.1 - 3e-44 151.3 0.0 9.4e-44 149.7 0.0 1.7 1 1 0 1 1 1 1 HAD domain family 1 in Swiss Army Knife RNA repair proteins Ion_trans_2 PF07885.16 KXS13272.1 - 6.5e-22 77.3 26.0 1.1e-11 44.5 9.0 2.7 2 0 0 2 2 2 2 Ion channel ATPase_gene1 PF09527.10 KXS13272.1 - 0.072 13.3 0.1 0.072 13.3 0.1 3.1 3 0 0 3 3 3 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter Lactamase_B_4 PF13691.6 KXS13273.1 - 3.4e-11 42.6 0.0 1e-10 41.1 0.0 1.9 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B_2 PF12706.7 KXS13273.1 - 6.7e-08 32.3 0.2 0.01 15.4 0.0 2.5 2 0 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KXS13273.1 - 0.035 14.1 0.1 0.14 12.1 0.1 2.0 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily DUF3951 PF13131.6 KXS13274.1 - 0.017 15.3 0.1 0.017 15.3 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3951) Helicase_C PF00271.31 KXS13275.1 - 2.9e-15 56.6 0.0 2e-14 53.9 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 KXS13275.1 - 5.8e-15 55.5 0.0 4.8e-07 29.7 0.0 2.3 2 0 0 2 2 2 2 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 KXS13275.1 - 4.7e-12 46.5 0.6 1.4e-11 44.9 0.6 1.9 1 0 0 1 1 1 1 RecQ zinc-binding DUF3459 PF11941.8 KXS13275.1 - 0.021 15.2 3.3 0.17 12.3 0.0 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF3459) CAP PF00188.26 KXS13276.1 - 1.9e-26 93.3 2.1 3e-26 92.7 2.1 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family AMP-binding PF00501.28 KXS13278.1 - 1.8e-76 257.5 0.0 2.3e-76 257.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXS13278.1 - 3.2e-12 47.3 0.2 6.4e-12 46.3 0.2 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain SAP PF02037.27 KXS13278.1 - 0.053 13.3 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 SAP domain CorA PF01544.18 KXS13279.1 - 1.9e-07 30.7 0.0 2.9e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DDE_3 PF13358.6 KXS13283.1 - 3e-09 36.8 0.0 1.3e-08 34.7 0.0 1.8 1 1 0 1 1 1 1 DDE superfamily endonuclease Tropomyosin PF00261.20 KXS13285.1 - 6.4e-08 32.3 36.4 6.4e-08 32.3 36.4 12.6 5 3 7 13 13 13 4 Tropomyosin Cation_efflux PF01545.21 KXS13286.1 - 2e-41 141.9 8.6 2.6e-39 135.0 8.6 2.2 1 1 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KXS13286.1 - 1.4e-15 57.2 4.7 3.4e-11 43.1 0.3 2.6 2 0 0 2 2 2 2 Dimerisation domain of Zinc Transporter GPW_gp25 PF04965.14 KXS13286.1 - 0.039 13.7 0.2 0.47 10.3 0.0 2.2 2 0 0 2 2 2 0 Gene 25-like lysozyme Glycogen_syn PF05693.13 KXS13287.1 - 3e-290 964.4 0.0 6.7e-240 798.0 0.0 2.0 2 0 0 2 2 2 2 Glycogen synthase Glycos_transf_1 PF00534.20 KXS13287.1 - 8.3e-06 25.4 0.0 0.00016 21.3 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KXS13287.1 - 0.00018 21.9 0.0 0.0079 16.6 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferases group 1 Abhydrolase_1 PF00561.20 KXS13288.1 - 3.6e-15 56.3 0.1 1.3e-14 54.5 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXS13288.1 - 5.6e-14 53.3 0.7 5.6e-14 53.3 0.7 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXS13288.1 - 5e-12 45.6 0.0 2.1e-11 43.5 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KXS13288.1 - 0.011 15.3 0.2 0.06 12.8 0.1 2.0 2 0 0 2 2 2 0 Prolyl oligopeptidase family FSH1 PF03959.13 KXS13288.1 - 0.13 11.9 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase (FSH1) HisKA PF00512.25 KXS13288.1 - 1.3 9.1 4.1 2 8.5 0.2 2.3 2 0 0 2 2 2 0 His Kinase A (phospho-acceptor) domain WD40 PF00400.32 KXS13289.1 - 6.4e-12 45.8 11.0 1.2e-05 25.9 0.3 5.7 7 0 0 7 7 7 3 WD domain, G-beta repeat Nup160 PF11715.8 KXS13289.1 - 0.0066 15.1 0.1 0.011 14.4 0.1 1.3 1 0 0 1 1 1 1 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 KXS13289.1 - 0.05 13.9 0.0 5.4 7.4 0.0 3.4 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Epimerase PF01370.21 KXS13290.1 - 5.8e-53 179.8 0.0 9.3e-53 179.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXS13290.1 - 2.7e-15 56.6 0.1 1.4e-14 54.2 0.0 1.8 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KXS13290.1 - 0.00018 20.6 0.0 0.0004 19.5 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KXS13290.1 - 0.0014 17.8 0.4 0.02 14.0 0.4 2.2 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KXS13290.1 - 0.078 12.1 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain TSNR_N PF04705.12 KXS13290.1 - 0.16 12.1 0.0 0.6 10.2 0.0 1.9 2 0 0 2 2 2 0 Thiostrepton-resistance methylase, N terminus Pkinase PF00069.25 KXS13292.1 - 3.6e-46 157.7 0.0 4.4e-46 157.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS13292.1 - 8.8e-16 58.0 0.0 1.8e-15 56.9 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KXS13292.1 - 0.057 12.8 0.0 0.084 12.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KXS13292.1 - 0.12 12.0 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 KXS13292.1 - 0.17 11.4 0.0 0.24 11.0 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Hist_deacetyl PF00850.19 KXS13295.1 - 2.1e-72 244.2 1.5 2.5e-72 243.9 1.5 1.0 1 0 0 1 1 1 1 Histone deacetylase domain PLAC8 PF04749.17 KXS13296.1 - 8e-20 71.7 17.1 1.1e-19 71.3 17.1 1.2 1 0 0 1 1 1 1 PLAC8 family Forkhead PF00250.18 KXS13297.1 - 0.016 15.5 0.1 0.21 11.9 0.0 2.5 3 0 0 3 3 3 0 Forkhead domain Kei1 PF08552.11 KXS13300.1 - 1 9.2 2.3 0.93 9.3 0.1 2.0 2 0 0 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 ADH_zinc_N PF00107.26 KXS13301.1 - 5.7e-11 42.5 0.0 9.7e-11 41.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXS13301.1 - 9.5e-11 42.9 0.0 1.8e-10 42.0 0.0 1.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXS13301.1 - 1.6e-09 37.6 0.0 3.6e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 KXS13301.1 - 0.014 14.7 2.6 0.036 13.4 0.9 2.0 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain CMD PF02627.20 KXS13302.1 - 1.1e-18 67.0 0.1 1.5e-18 66.6 0.1 1.2 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family ASFV_360 PF01671.16 KXS13302.1 - 0.16 11.4 0.0 0.19 11.2 0.0 1.1 1 0 0 1 1 1 0 African swine fever virus multigene family 360 protein zf-RING_2 PF13639.6 KXS13305.1 - 1.1e-12 48.1 4.3 1.7e-12 47.4 4.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KXS13305.1 - 4.3e-10 39.1 1.1 7.4e-10 38.4 1.1 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KXS13305.1 - 2.5e-09 36.8 3.5 4e-09 36.2 3.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXS13305.1 - 1.1e-07 31.6 1.5 1.7e-07 31.0 1.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KXS13305.1 - 4.9e-06 26.7 5.2 1.4e-05 25.2 5.2 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 KXS13305.1 - 0.00025 20.9 2.2 0.00039 20.2 2.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXS13305.1 - 0.00064 19.7 0.4 0.0013 18.7 0.1 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KXS13305.1 - 0.00073 19.5 1.6 0.0011 18.9 1.6 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 KXS13305.1 - 0.00094 19.2 0.2 0.0016 18.4 0.2 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger MGTL PF17059.5 KXS13305.1 - 0.018 14.8 0.1 0.018 14.8 0.1 2.6 2 0 0 2 2 2 0 MgtA leader peptide zf-C3H2C3 PF17122.5 KXS13305.1 - 0.03 14.4 1.6 0.093 12.8 1.6 1.8 1 1 0 1 1 1 0 Zinc-finger Prok-RING_4 PF14447.6 KXS13305.1 - 0.04 13.8 3.0 0.083 12.8 3.0 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KXS13305.1 - 0.055 13.6 0.6 0.12 12.6 0.6 1.6 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Zn_ribbon_17 PF17120.5 KXS13305.1 - 0.073 12.7 4.8 0.14 11.8 4.7 1.6 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING-like PF08746.11 KXS13305.1 - 0.25 11.7 2.3 0.48 10.8 2.3 1.5 1 0 0 1 1 1 0 RING-like domain zf-RING_4 PF14570.6 KXS13305.1 - 0.38 10.6 3.1 0.68 9.8 3.1 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 KXS13305.1 - 1.6 9.0 5.4 15 5.9 5.4 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain F-box-like PF12937.7 KXS13307.1 - 1 9.3 4.9 0.44 10.5 1.1 2.6 2 1 0 2 2 2 0 F-box-like EF-hand_5 PF13202.6 KXS13308.1 - 0.014 14.9 0.0 0.031 13.8 0.0 1.6 1 0 0 1 1 1 0 EF hand EF-hand_1 PF00036.32 KXS13308.1 - 0.044 13.3 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 EF hand RNA_polI_A34 PF08208.11 KXS13308.1 - 3.6 7.6 11.1 0.65 10.0 0.1 2.4 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 zf-C3HC4_3 PF13920.6 KXS13312.1 - 1.6e-12 47.0 8.0 1.6e-12 47.0 8.0 1.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KXS13312.1 - 2.2e-05 24.2 8.0 3.8e-05 23.5 8.0 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KXS13312.1 - 0.0011 19.3 10.2 0.0011 19.3 10.2 1.6 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 KXS13312.1 - 0.011 15.6 8.7 0.011 15.6 8.7 2.1 2 1 0 2 2 2 0 zinc-RING finger domain zf-FPG_IleRS PF06827.14 KXS13312.1 - 0.72 9.8 6.4 6.8 6.7 0.8 2.7 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS zf-C3HC4 PF00097.25 KXS13312.1 - 1.6 8.7 14.7 0.14 12.0 9.2 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXS13312.1 - 1.7 8.6 14.5 0.17 11.7 9.8 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) ABC_membrane PF00664.23 KXS13313.1 - 7.5e-68 229.1 19.8 2.1e-36 126.0 6.2 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KXS13313.1 - 1.7e-50 171.1 0.0 7.1e-29 101.1 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KXS13313.1 - 1.1e-08 34.8 0.0 0.0011 18.5 0.0 3.9 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KXS13313.1 - 5.2e-05 23.7 5.1 0.11 12.9 0.1 2.8 3 0 0 3 3 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 KXS13313.1 - 0.00059 19.9 0.1 0.56 10.3 0.1 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase DEAD PF00270.29 KXS13313.1 - 0.0046 16.7 0.1 0.52 10.0 0.1 2.7 2 1 0 2 2 2 1 DEAD/DEAH box helicase RsgA_GTPase PF03193.16 KXS13313.1 - 0.0054 16.7 1.9 0.15 12.0 0.4 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 KXS13313.1 - 0.0069 16.1 0.5 2.4 8.0 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA PF00004.29 KXS13313.1 - 0.016 15.7 0.6 2.5 8.5 0.1 3.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 KXS13313.1 - 0.02 14.1 0.3 0.34 10.0 0.2 2.4 2 0 0 2 2 2 0 NB-ARC domain AAA_24 PF13479.6 KXS13313.1 - 0.022 14.5 0.1 0.18 11.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KXS13313.1 - 0.048 13.2 1.4 3.2 7.2 0.1 2.9 3 0 0 3 3 3 0 P-loop containing dynein motor region DUF87 PF01935.17 KXS13313.1 - 0.055 13.6 0.1 0.055 13.6 0.1 2.9 3 0 0 3 3 3 0 Helicase HerA, central domain AAA_21 PF13304.6 KXS13313.1 - 0.055 13.3 0.8 33 4.2 0.6 3.7 3 1 1 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system IstB_IS21 PF01695.17 KXS13313.1 - 0.22 11.2 1.2 17 5.1 0.0 3.1 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_11 PF13086.6 KXS13313.1 - 0.33 10.7 3.8 1.4 8.7 2.2 2.3 3 0 0 3 3 2 0 AAA domain TIP49 PF06068.13 KXS13313.1 - 0.34 10.1 2.2 0.75 8.9 0.3 2.2 2 0 0 2 2 2 0 TIP49 P-loop domain Zeta_toxin PF06414.12 KXS13313.1 - 0.38 10.0 2.6 4.2 6.6 0.3 2.8 3 0 0 3 3 3 0 Zeta toxin AAA_22 PF13401.6 KXS13313.1 - 0.43 10.8 6.8 18 5.6 0.3 3.7 3 1 0 3 3 3 0 AAA domain DUF2207 PF09972.9 KXS13313.1 - 0.8 8.4 2.3 1.6 7.4 0.1 2.4 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) AAA_25 PF13481.6 KXS13313.1 - 1.1 8.8 7.7 26 4.3 0.2 3.4 3 0 0 3 3 3 0 AAA domain p450 PF00067.22 KXS13314.1 - 7.4e-69 232.7 0.0 1.1e-68 232.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Acylphosphatase PF00708.18 KXS13315.1 - 1.6e-24 86.1 0.2 1.8e-24 85.9 0.2 1.0 1 0 0 1 1 1 1 Acylphosphatase MFS_1 PF07690.16 KXS13316.1 - 5.2e-19 68.4 36.3 5.8e-16 58.4 25.3 3.2 3 1 0 3 3 3 2 Major Facilitator Superfamily DUF2244 PF10003.9 KXS13316.1 - 0.34 10.6 0.1 0.34 10.6 0.1 3.0 3 0 0 3 3 3 0 Integral membrane protein (DUF2244) DUF4202 PF13875.6 KXS13319.1 - 1e-39 136.4 0.0 1.7e-39 135.7 0.0 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4202) Troponin-I_N PF11636.8 KXS13319.1 - 2.2 8.3 6.9 6.4 6.8 6.9 1.8 1 0 0 1 1 1 0 Troponin I residues 1-32 DUF2236 PF09995.9 KXS13321.1 - 7.6e-24 85.2 2.5 1.3e-23 84.4 2.5 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) PsaL PF02605.15 KXS13321.1 - 0.12 12.1 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 Photosystem I reaction centre subunit XI MFS_1 PF07690.16 KXS13322.1 - 1e-22 80.5 46.6 4.2e-16 58.8 20.5 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily MBOAT_2 PF13813.6 KXS13323.1 - 1.2e-08 35.1 3.1 0.0001 22.5 0.1 2.6 2 0 0 2 2 2 2 Membrane bound O-acyl transferase family CN_hydrolase PF00795.22 KXS13324.1 - 2.6e-60 204.0 0.0 3.1e-60 203.7 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase PA PF02225.22 KXS13324.1 - 0.39 10.8 1.5 8 6.6 0.2 2.8 3 1 0 3 3 3 0 PA domain Glyco_hydro_32N PF00251.20 KXS13325.1 - 1.3e-23 84.0 7.7 7.1e-21 75.1 2.8 3.3 2 2 0 2 2 2 2 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 KXS13325.1 - 4.2e-19 69.1 0.0 6.8e-19 68.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Ldr_toxin PF13940.6 KXS13325.1 - 0.011 15.8 0.0 0.025 14.6 0.0 1.6 1 0 0 1 1 1 0 Toxin Ldr, type I toxin-antitoxin system DUF4975 PF16346.5 KXS13325.1 - 0.022 14.9 0.0 0.086 12.9 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4975) Pkinase PF00069.25 KXS13327.1 - 1.8e-57 194.7 0.0 2.3e-57 194.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS13327.1 - 9.3e-32 110.3 0.0 5.1e-30 104.6 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 KXS13327.1 - 0.0023 17.6 0.1 0.0085 15.7 0.1 1.8 1 1 0 1 1 1 1 RIO1 family APH PF01636.23 KXS13327.1 - 0.013 15.4 0.2 0.14 12.1 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.6 KXS13327.1 - 0.029 13.7 0.0 0.31 10.3 0.0 2.1 2 0 0 2 2 2 0 Kinase-like SCAB-ABD PF16711.5 KXS13327.1 - 0.037 13.9 0.4 0.13 12.2 0.4 1.9 2 0 0 2 2 2 0 Actin-binding domain of plant-specific actin-binding protein DUF5401 PF17380.2 KXS13327.1 - 0.23 9.5 1.6 0.34 8.9 1.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) DIOX_N PF14226.6 KXS13328.1 - 4.3e-30 104.9 0.1 1.4e-29 103.3 0.0 1.9 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KXS13328.1 - 2.8e-20 72.7 0.0 4.5e-20 72.0 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Methyltransf_11 PF08241.12 KXS13329.1 - 1.8e-10 41.3 0.0 3.6e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXS13329.1 - 3.2e-06 27.8 0.0 8.9e-06 26.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXS13329.1 - 2.8e-05 24.0 0.0 4e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXS13329.1 - 0.0026 17.1 0.0 0.0058 16.0 0.0 1.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 KXS13329.1 - 0.0051 16.6 0.0 0.033 14.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXS13329.1 - 0.014 16.1 0.0 0.072 13.8 0.0 2.1 2 1 0 2 2 2 0 Methyltransferase domain MSA-2c PF12238.8 KXS13330.1 - 1.3 8.9 3.7 2 8.4 3.7 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c Sds3 PF08598.11 KXS13332.1 - 0.0038 17.3 4.8 0.0038 17.3 4.8 2.0 2 1 0 2 2 2 1 Sds3-like Nicastrin PF05450.15 KXS13332.1 - 0.75 9.2 1.9 1.4 8.3 1.9 1.3 1 0 0 1 1 1 0 Nicastrin Spt5-NGN PF03439.13 KXS13333.1 - 6e-11 42.1 0.0 4.6e-06 26.4 0.0 2.4 2 0 0 2 2 2 2 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.29 KXS13333.1 - 1.1e-06 28.4 25.8 0.27 11.2 3.3 6.6 6 0 0 6 6 6 4 KOW motif Spt5_N PF11942.8 KXS13333.1 - 1.2e-06 29.4 9.8 1.2e-06 29.4 9.8 2.3 2 0 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal CTD PF12815.7 KXS13333.1 - 1.6e-05 25.3 19.7 3.2e-05 24.4 16.8 2.6 1 1 1 2 2 2 2 Spt5 C-terminal nonapeptide repeat binding Spt4 YajC PF02699.15 KXS13333.1 - 0.0019 18.0 3.6 0.096 12.6 0.6 2.9 3 0 0 3 3 3 2 Preprotein translocase subunit UvrB PF12344.8 KXS13336.1 - 0.17 11.8 0.2 0.26 11.2 0.2 1.3 1 0 0 1 1 1 0 Ultra-violet resistance protein B SNF PF00209.18 KXS13338.1 - 1.7e-91 307.5 35.9 1.7e-55 188.8 16.9 3.0 1 1 2 3 3 3 3 Sodium:neurotransmitter symporter family DUF378 PF04070.12 KXS13338.1 - 0.075 12.9 8.4 1.2 9.1 3.6 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF378) BIR PF00653.21 KXS13339.1 - 1e-05 26.1 2.6 1e-05 26.1 2.6 2.5 2 1 0 2 2 2 1 Inhibitor of Apoptosis domain Cyclin_N PF00134.23 KXS13341.1 - 1.2e-09 38.0 0.0 1.9e-08 34.1 0.0 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KXS13341.1 - 0.00091 19.3 0.0 0.0023 18.0 0.0 1.7 2 0 0 2 2 2 1 Cyclin, C-terminal domain HTH_IclR PF09339.10 KXS13342.1 - 0.003 17.3 0.0 0.019 14.8 0.0 2.2 2 0 0 2 2 2 1 IclR helix-turn-helix domain Spc7 PF08317.11 KXS13342.1 - 0.12 11.2 4.2 0.037 12.9 0.7 1.9 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF4795 PF16043.5 KXS13342.1 - 0.16 11.6 0.9 1.5 8.4 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) adh_short PF00106.25 KXS13345.1 - 7e-14 51.7 3.5 1e-13 51.2 3.5 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXS13345.1 - 0.0017 18.3 1.2 0.0025 17.7 0.2 1.7 1 1 1 2 2 2 1 KR domain MIP PF00230.20 KXS13347.1 - 3.7e-55 187.1 16.1 5e-55 186.7 16.1 1.1 1 0 0 1 1 1 1 Major intrinsic protein Wzy_C PF04932.15 KXS13347.1 - 7.6 6.1 11.1 0.041 13.5 0.7 2.1 2 1 0 2 2 2 0 O-Antigen ligase ECH_1 PF00378.20 KXS13348.1 - 9.6e-27 93.9 0.2 2.1e-26 92.8 0.2 1.5 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXS13348.1 - 2.3e-11 43.8 0.4 3.4e-11 43.2 0.4 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Ubiq-Cytc-red_N PF09165.10 KXS13348.1 - 7.2 7.6 9.3 2.1 9.3 0.9 3.2 3 0 0 3 3 3 0 Ubiquinol-cytochrome c reductase 8 kDa, N-terminal Abhydrolase_6 PF12697.7 KXS13350.1 - 6e-05 23.7 1.4 9e-05 23.2 1.4 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXS13350.1 - 0.057 12.7 0.0 0.21 10.8 0.0 1.8 2 0 0 2 2 2 0 Serine aminopeptidase, S33 SRC-1 PF08832.10 KXS13350.1 - 0.17 13.0 0.0 0.37 11.9 0.0 1.5 1 0 0 1 1 1 0 Steroid receptor coactivator DUF4486 PF14858.6 KXS13351.1 - 0.0074 14.8 0.0 0.011 14.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4486) DUF2225 PF09986.9 KXS13351.1 - 0.039 13.7 0.1 1.7 8.3 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) ATG16 PF08614.11 KXS13351.1 - 0.19 12.0 6.6 0.073 13.3 1.6 2.3 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) FIVAR PF07554.13 KXS13352.1 - 0.03 15.1 0.0 0.067 14.0 0.0 1.6 1 0 0 1 1 1 0 FIVAR domain THOC7 PF05615.13 KXS13352.1 - 0.051 13.9 5.4 2.1 8.6 0.4 2.3 2 0 0 2 2 2 0 Tho complex subunit 7 WH2 PF02205.20 KXS13353.1 - 0.00043 20.0 0.3 0.00082 19.1 0.3 1.5 1 0 0 1 1 1 1 WH2 motif HTH_IclR PF09339.10 KXS13353.1 - 0.012 15.4 0.0 0.043 13.6 0.0 1.9 2 0 0 2 2 2 0 IclR helix-turn-helix domain Dimer_Tnp_hAT PF05699.14 KXS13354.1 - 0.00027 20.6 0.0 0.00085 19.1 0.0 2.0 1 1 0 1 1 1 1 hAT family C-terminal dimerisation region DUF2774 PF11242.8 KXS13354.1 - 0.12 12.6 0.1 0.31 11.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2774) Glyco_hydro_53 PF07745.13 KXS13356.1 - 5e-96 321.6 0.0 5.8e-96 321.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 Metallophos PF00149.28 KXS13357.1 - 8.7e-36 124.3 0.7 1.5e-35 123.5 0.7 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF5378 PF17349.2 KXS13357.1 - 0.065 12.5 0.0 0.099 12.0 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5378) Mtc PF03820.17 KXS13357.1 - 0.1 11.6 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Tricarboxylate carrier DIOX_N PF14226.6 KXS13358.1 - 1.4e-23 83.9 0.0 2.3e-23 83.2 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KXS13358.1 - 8.7e-18 64.7 0.1 1.7e-17 63.7 0.1 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily FAM72 PF14976.6 KXS13360.1 - 2.8e-55 186.4 3.0 3.4e-55 186.2 3.0 1.0 1 0 0 1 1 1 1 FAM72 protein Yippee-Mis18 PF03226.14 KXS13360.1 - 1.5 9.1 7.1 3.6 7.9 7.1 1.7 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly MFS_1 PF07690.16 KXS13361.1 - 3e-50 171.1 44.8 4.6e-50 170.5 44.8 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXS13361.1 - 1e-13 51.0 14.3 1e-13 51.0 14.3 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.13 KXS13361.1 - 2.5e-12 46.1 26.7 2.5e-12 46.1 26.7 1.6 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) CBP_BcsS PF17036.5 KXS13361.1 - 0.084 12.8 0.2 0.26 11.2 0.1 1.8 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsS YtpI PF14007.6 KXS13361.1 - 4.7 7.4 6.7 1.9 8.7 0.5 2.7 2 0 0 2 2 2 0 YtpI-like protein MFS_1 PF07690.16 KXS13363.1 - 4.4e-49 167.3 38.3 8.2e-49 166.4 38.3 1.5 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KXS13363.1 - 2e-16 59.6 26.1 3.4e-16 58.8 26.1 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KXS13363.1 - 2.3e-14 53.1 14.6 2.3e-14 53.1 14.6 2.6 3 1 0 3 3 3 1 Sugar (and other) transporter DUF2530 PF10745.9 KXS13363.1 - 3.1 8.1 10.3 10 6.4 0.4 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) ECH_1 PF00378.20 KXS13364.1 - 8.6e-35 120.2 0.0 9.9e-34 116.8 0.0 1.9 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXS13364.1 - 6.5e-17 62.0 0.0 1.1e-16 61.3 0.0 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase MFS_1 PF07690.16 KXS13365.1 - 1.1e-48 166.0 47.4 1.1e-48 166.0 47.4 2.2 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 KXS13365.1 - 0.0037 16.2 24.0 0.037 12.9 6.1 2.2 2 0 0 2 2 2 2 MFS_1 like family MotA_ExbB PF01618.16 KXS13365.1 - 0.0083 15.9 4.0 0.55 10.0 0.5 3.0 2 0 0 2 2 2 2 MotA/TolQ/ExbB proton channel family RVT_thumb PF06817.14 KXS13365.1 - 0.049 13.5 0.0 0.088 12.7 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase thumb domain DUF2919 PF11143.8 KXS13365.1 - 0.068 13.5 1.7 0.22 11.8 0.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2919) DUF4349 PF14257.6 KXS13365.1 - 0.24 10.8 0.2 0.66 9.4 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) OATP PF03137.20 KXS13365.1 - 0.44 8.8 14.2 0.061 11.6 0.8 3.4 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family DUF4286 PF14114.6 KXS13366.1 - 1.5e-08 35.0 0.0 9e-08 32.5 0.0 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4286) MIF4G_like PF09088.11 KXS13366.1 - 0.094 12.5 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 MIF4G like WW_1 PF18507.1 KXS13367.1 - 0.1 12.3 0.4 0.2 11.4 0.4 1.4 1 0 0 1 1 1 0 WW domain Ada3 PF10198.9 KXS13368.1 - 8.5e-26 90.7 0.1 2.2e-25 89.4 0.1 1.7 1 0 0 1 1 1 1 Histone acetyltransferases subunit 3 HTH_50 PF18024.1 KXS13368.1 - 0.091 12.4 0.7 0.23 11.1 0.7 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain Sulfate_transp PF00916.20 KXS13369.1 - 1e-108 363.5 17.9 1.3e-108 363.2 17.9 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KXS13369.1 - 1.5e-11 43.9 0.0 2.9e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 KXS13369.1 - 0.01 16.1 0.3 0.033 14.5 0.3 1.8 2 0 0 2 2 2 0 STAS domain MFS_MOT1 PF16983.5 KXS13369.1 - 0.02 15.3 4.6 0.02 15.3 4.6 2.9 2 1 0 2 2 2 0 Molybdate transporter of MFS superfamily YebO PF13974.6 KXS13369.1 - 0.12 12.4 0.0 0.36 10.9 0.0 1.7 1 0 0 1 1 1 0 YebO-like protein DUF1764 PF08576.10 KXS13370.1 - 6.7e-17 62.2 13.1 1.3e-16 61.3 1.1 2.4 1 1 1 2 2 2 2 Eukaryotic protein of unknown function (DUF1764) DUF4551 PF15087.6 KXS13370.1 - 2.9 6.6 6.5 3.2 6.5 6.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) NTP_transferase PF00483.23 KXS13371.1 - 7.7e-50 169.8 0.0 1.1e-49 169.3 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 KXS13371.1 - 5.2e-16 57.7 14.0 2.1e-09 36.7 3.0 3.7 1 1 3 4 4 4 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 KXS13371.1 - 2.5e-10 40.9 0.0 3.5e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 KXS13371.1 - 0.013 15.3 6.1 0.013 15.3 6.1 2.6 4 0 0 4 4 4 0 Hexapeptide repeat of succinyl-transferase IspD PF01128.19 KXS13371.1 - 0.026 14.3 0.0 0.085 12.6 0.0 1.9 2 0 0 2 2 2 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase DUF4954 PF16314.5 KXS13371.1 - 0.12 10.5 0.4 0.17 10.0 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) Zip PF02535.22 KXS13372.1 - 5.7e-17 61.9 0.8 8e-12 45.0 0.3 2.1 2 0 0 2 2 2 2 ZIP Zinc transporter RWD PF05773.22 KXS13374.1 - 7.1e-11 42.4 0.0 1.3e-10 41.6 0.0 1.4 1 0 0 1 1 1 1 RWD domain IBR PF01485.21 KXS13374.1 - 1.7e-09 37.7 0.1 1.7e-09 37.7 0.1 3.0 3 0 0 3 3 3 1 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 KXS13374.1 - 0.00058 19.7 3.2 0.00058 19.7 3.2 2.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXS13374.1 - 0.0028 18.0 14.5 0.0032 17.8 7.2 2.7 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 KXS13374.1 - 0.0063 16.5 7.7 0.0063 16.5 7.7 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KXS13374.1 - 0.0079 16.2 5.6 0.0079 16.2 5.6 2.8 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KXS13374.1 - 0.015 15.2 14.4 0.019 14.8 6.3 2.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Copper-fist PF00649.18 KXS13374.1 - 0.031 13.8 0.9 0.23 11.0 0.0 2.5 2 0 0 2 2 2 0 Copper fist DNA binding domain zf-RING_11 PF17123.5 KXS13374.1 - 1.1 9.0 11.5 2.3 8.1 10.5 2.1 2 0 0 2 2 2 0 RING-like zinc finger CEBP_ZZ PF16366.5 KXS13374.1 - 4.1 7.7 11.3 7.7 6.8 3.2 2.6 2 0 0 2 2 2 0 Cytoplasmic polyadenylation element-binding protein ZZ domain Thymidylat_synt PF00303.19 KXS13375.1 - 1.8e-95 319.1 0.0 2.2e-95 318.8 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase RhodobacterPufX PF11511.8 KXS13376.1 - 0.037 13.6 0.5 0.08 12.6 0.5 1.5 1 0 0 1 1 1 0 Intrinsic membrane protein PufX Collagen PF01391.18 KXS13377.1 - 0.0003 20.5 11.3 0.0003 20.5 11.3 2.9 2 0 0 2 2 2 1 Collagen triple helix repeat (20 copies) CAP_N PF01213.19 KXS13378.1 - 5.5 6.4 6.5 7.2 6.0 6.5 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal YccF PF03733.13 KXS13379.1 - 4.7e-19 68.8 32.0 1.6e-11 44.7 10.8 2.6 3 0 0 3 3 3 2 Inner membrane component domain FAM199X PF15814.5 KXS13382.1 - 0.042 12.9 0.0 0.077 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein family FAM199X Band_7 PF01145.25 KXS13384.1 - 6e-27 94.8 2.9 7.5e-27 94.5 2.9 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 KXS13384.1 - 0.026 14.2 0.6 0.036 13.8 0.6 1.3 1 0 0 1 1 1 0 SPFH domain-Band 7 family LRS4 PF10422.9 KXS13384.1 - 0.087 12.4 0.5 0.12 12.0 0.5 1.2 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 DUF2605 PF10792.9 KXS13384.1 - 1 9.3 3.9 5.1 7.1 0.4 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF2605) MFS_1 PF07690.16 KXS13386.1 - 2.3e-40 138.6 29.7 3.4e-40 138.1 29.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily HTH_33 PF13592.6 KXS13388.1 - 0.0001 21.9 1.4 0.00018 21.1 0.0 2.1 2 0 0 2 2 2 1 Winged helix-turn helix HTH_23 PF13384.6 KXS13388.1 - 0.00011 21.8 0.2 0.12 12.2 0.0 2.7 2 1 0 2 2 2 2 Homeodomain-like domain HTH_32 PF13565.6 KXS13388.1 - 0.00017 22.1 0.0 0.00038 21.0 0.0 1.6 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.6 KXS13388.1 - 0.0024 17.8 0.1 0.23 11.5 0.0 2.5 2 0 0 2 2 2 1 Winged helix-turn helix DDE_3 PF13358.6 KXS13388.1 - 0.0041 16.9 0.0 0.0083 15.9 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_IS630 PF01710.16 KXS13388.1 - 0.015 15.3 0.3 0.048 13.7 0.3 1.8 1 1 0 1 1 1 0 Transposase HTH_Tnp_Tc3_2 PF01498.18 KXS13388.1 - 0.039 14.2 0.2 0.73 10.1 0.1 2.2 2 0 0 2 2 2 0 Transposase TCTP PF00838.17 KXS13388.1 - 0.077 13.3 0.1 0.12 12.7 0.1 1.4 1 1 0 1 1 1 0 Translationally controlled tumour protein HTH_ABP1_N PF18107.1 KXS13388.1 - 0.12 12.1 0.0 0.28 10.9 0.0 1.6 1 0 0 1 1 1 0 Fission yeast centromere protein N-terminal domain Dimer_Tnp_hAT PF05699.14 KXS13389.1 - 1.2e-18 66.7 0.0 1.4e-18 66.5 0.0 1.1 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Rubredoxin PF00301.20 KXS13390.1 - 0.024 14.7 0.4 0.063 13.3 0.4 1.7 1 0 0 1 1 1 0 Rubredoxin p450 PF00067.22 KXS13392.1 - 1.5e-24 86.6 0.0 1.2e-22 80.3 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Rhomboid_SP PF12595.8 KXS13392.1 - 0.15 11.4 3.9 0.22 10.8 3.9 1.3 1 0 0 1 1 1 0 Rhomboid serine protease RRM_1 PF00076.22 KXS13393.1 - 2.3e-06 27.3 0.0 4e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NTF2 PF02136.20 KXS13393.1 - 2.4e-06 28.1 0.0 1.9e-05 25.2 0.0 2.1 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain SnoaL_2 PF12680.7 KXS13393.1 - 0.073 13.7 0.2 0.24 12.0 0.2 1.9 1 1 0 1 1 1 0 SnoaL-like domain Actin PF00022.19 KXS13394.1 - 2.3e-125 418.4 0.0 2.8e-124 414.8 0.0 1.9 1 1 0 1 1 1 1 Actin Dcc1 PF09724.9 KXS13395.1 - 3.7e-69 233.6 0.0 4.4e-69 233.3 0.0 1.1 1 0 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 Strep_his_triad PF04270.13 KXS13395.1 - 0.15 12.1 0.0 0.38 10.8 0.0 1.7 1 0 0 1 1 1 0 Streptococcal histidine triad protein PD40 PF07676.12 KXS13396.1 - 0.12 12.3 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat PQQ_2 PF13360.6 KXS13396.1 - 0.17 11.4 0.0 0.21 11.2 0.0 1.1 1 0 0 1 1 1 0 PQQ-like domain DprA_WH PF17782.1 KXS13397.1 - 0.018 15.2 0.0 0.045 13.9 0.0 1.7 1 0 0 1 1 1 0 DprA winged helix domain WD40 PF00400.32 KXS13398.1 - 0.16 12.9 1.2 0.98 10.4 0.3 2.6 2 0 0 2 2 2 0 WD domain, G-beta repeat Lipase_GDSL_2 PF13472.6 KXS13400.1 - 3.7e-16 60.0 0.0 4.5e-16 59.8 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KXS13400.1 - 5.7e-05 23.2 0.0 0.00015 21.8 0.0 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Ras PF00071.22 KXS13402.1 - 2.2e-62 209.4 0.2 2.6e-62 209.2 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXS13402.1 - 9.7e-35 119.4 0.1 1.5e-34 118.8 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXS13402.1 - 2.3e-12 46.7 0.1 2.8e-12 46.5 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KXS13402.1 - 3.9e-07 30.1 0.1 6.5e-07 29.4 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 KXS13402.1 - 3.7e-05 24.0 0.0 0.00057 20.2 0.0 2.3 1 1 0 1 1 1 1 AAA domain GTP_EFTU PF00009.27 KXS13402.1 - 0.00051 19.6 0.2 0.0024 17.5 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KXS13402.1 - 0.00086 19.2 0.2 0.019 14.8 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase FAD-SLDH PF12318.8 KXS13402.1 - 0.0076 16.3 0.1 0.02 15.0 0.0 1.7 2 0 0 2 2 2 1 Membrane bound FAD containing D-sorbitol dehydrogenase Gtr1_RagA PF04670.12 KXS13402.1 - 0.011 15.1 0.1 0.016 14.5 0.1 1.4 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KXS13402.1 - 0.024 14.1 0.0 0.059 12.8 0.0 1.6 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 KXS13402.1 - 0.027 14.2 0.0 0.046 13.5 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.6 KXS13402.1 - 0.028 14.1 0.1 0.067 12.9 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KXS13402.1 - 0.029 14.8 0.1 0.048 14.0 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 KXS13402.1 - 0.035 14.6 0.1 0.063 13.8 0.1 1.5 1 1 0 1 1 1 0 ABC transporter TniB PF05621.11 KXS13402.1 - 0.053 12.9 0.0 0.19 11.1 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein AAA_28 PF13521.6 KXS13402.1 - 0.085 13.1 0.1 0.67 10.2 0.1 2.2 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.18 KXS13402.1 - 0.097 12.2 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B KAP_NTPase PF07693.14 KXS13402.1 - 0.1 11.8 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain MCM PF00493.23 KXS13402.1 - 0.11 11.6 0.0 0.2 10.7 0.0 1.5 1 0 0 1 1 1 0 MCM P-loop domain AAA_14 PF13173.6 KXS13402.1 - 0.12 12.4 0.1 0.32 11.0 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_21 PF13304.6 KXS13402.1 - 0.14 12.0 0.1 0.24 11.2 0.1 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system E1-E2_ATPase PF00122.20 KXS13403.1 - 5.5e-36 123.8 4.4 1e-35 122.9 4.4 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 KXS13403.1 - 3.6e-33 115.6 0.0 6e-33 114.9 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 KXS13403.1 - 2.4e-16 59.9 0.0 7.1e-08 32.8 0.0 2.7 2 0 0 2 2 2 2 Heavy-metal-associated domain Hydrolase_3 PF08282.12 KXS13403.1 - 0.00056 19.7 0.0 0.0013 18.5 0.0 1.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KXS13403.1 - 0.13 12.7 0.1 0.9 9.9 0.0 2.5 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase Pkinase PF00069.25 KXS13405.1 - 1.5e-58 198.3 0.0 2.7e-58 197.4 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS13405.1 - 8.4e-35 120.3 0.0 5.7e-34 117.6 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Plk4_PB2 PF18409.1 KXS13405.1 - 7.7e-17 62.0 0.0 1.5e-16 61.1 0.0 1.5 1 0 0 1 1 1 1 Polo-like Kinase 4 Polo Box 2 Plk4_PB1 PF18190.1 KXS13405.1 - 1.8e-07 31.3 0.0 9.8e-07 28.9 0.0 2.3 2 1 0 2 2 2 1 Polo-like Kinase 4 Polo Box 1 Kinase-like PF14531.6 KXS13405.1 - 0.0024 17.2 0.0 0.0051 16.2 0.0 1.5 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KXS13405.1 - 0.012 15.3 0.0 0.023 14.3 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 KXS13405.1 - 0.018 13.9 0.0 0.031 13.0 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 KXS13405.1 - 0.019 14.9 0.3 0.019 14.9 0.3 2.1 2 1 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 KXS13405.1 - 0.13 11.6 0.1 0.21 10.9 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family POLO_box PF00659.18 KXS13405.1 - 0.22 11.7 0.0 0.46 10.7 0.0 1.5 1 0 0 1 1 1 0 POLO box duplicated region Haspin_kinase PF12330.8 KXS13405.1 - 0.23 10.3 0.1 0.4 9.6 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain UCH PF00443.29 KXS13406.1 - 3.2e-44 151.4 0.0 5.5e-44 150.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.31 KXS13406.1 - 7.1e-26 89.7 2.0 1.2e-13 50.7 0.1 2.6 2 0 0 2 2 2 2 UBA/TS-N domain zf-UBP PF02148.19 KXS13406.1 - 2.5e-25 88.6 11.7 1.4e-19 70.2 0.7 3.3 2 0 0 2 2 2 2 Zn-finger in ubiquitin-hydrolases and other protein zf-UBP_var PF17807.1 KXS13406.1 - 7.5e-24 83.3 1.8 9.3e-22 76.6 0.2 2.9 2 0 0 2 2 2 2 Variant UBP zinc finger UCH_1 PF13423.6 KXS13406.1 - 3.7e-10 39.9 1.6 2.9e-06 27.1 0.0 3.9 2 1 1 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase fn3_3 PF14686.6 KXS13406.1 - 0.012 15.3 0.1 5.1 6.9 0.0 2.4 2 0 0 2 2 2 0 Polysaccharide lyase family 4, domain II DUF3173 PF11372.8 KXS13406.1 - 0.15 11.9 0.0 1.8 8.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3173) SH3_1 PF00018.28 KXS13408.1 - 2e-05 24.1 0.0 6.7e-05 22.4 0.0 1.9 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 KXS13408.1 - 3.9e-05 23.4 0.0 0.00038 20.3 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 KXS13408.1 - 0.14 11.9 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Variant SH3 domain DUF4604 PF15377.6 KXS13409.1 - 0.011 16.2 2.2 0.011 16.2 2.2 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4604) DUF1664 PF07889.12 KXS13409.1 - 0.024 14.6 0.5 0.06 13.4 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) GCFC PF07842.12 KXS13409.1 - 0.17 11.5 0.1 0.36 10.4 0.1 1.5 1 0 0 1 1 1 0 GC-rich sequence DNA-binding factor-like protein K-box PF01486.17 KXS13409.1 - 0.35 11.1 2.4 8.8 6.6 0.0 3.3 3 1 1 4 4 4 0 K-box region adh_short PF00106.25 KXS13412.1 - 4.5e-20 71.9 0.0 2.9e-18 66.0 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXS13412.1 - 2.4e-17 63.3 0.0 1.2e-15 57.7 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXS13412.1 - 6.5e-07 29.4 0.0 1e-06 28.8 0.0 1.3 1 0 0 1 1 1 1 KR domain WBS_methylT PF12589.8 KXS13414.1 - 9.2e-22 77.6 1.5 1.5e-21 77.0 1.5 1.3 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.12 KXS13414.1 - 5e-11 43.1 0.0 8.8e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXS13414.1 - 6.2e-10 39.7 0.0 1.4e-09 38.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXS13414.1 - 3.4e-05 24.5 0.0 8e-05 23.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXS13414.1 - 0.00069 19.4 0.0 0.00098 18.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXS13414.1 - 0.0014 18.4 0.0 0.0024 17.7 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain AdoMet_MTase PF07757.13 KXS13414.1 - 0.0075 16.6 0.0 0.019 15.3 0.0 1.6 2 0 0 2 2 2 1 Predicted AdoMet-dependent methyltransferase CMAS PF02353.20 KXS13414.1 - 0.015 14.6 0.0 0.05 12.9 0.0 1.7 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.6 KXS13414.1 - 0.025 14.6 0.0 0.04 13.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 KXS13414.1 - 0.064 12.6 0.0 0.099 12.0 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family PCMT PF01135.19 KXS13414.1 - 0.084 12.6 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ribosomal_S13 PF00416.22 KXS13415.1 - 1.4e-19 70.7 1.5 1.9e-17 63.8 1.5 2.1 1 1 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 KXS13415.1 - 0.034 12.9 0.0 0.042 12.6 0.0 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) DUF4648 PF15505.6 KXS13415.1 - 0.037 14.9 0.2 0.07 14.0 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4648) Kinesin PF00225.23 KXS13416.1 - 2.1e-47 161.7 0.0 2.8e-47 161.3 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KXS13416.1 - 7.9e-19 68.1 0.0 1.9e-18 66.8 0.0 1.6 2 0 0 2 2 2 1 Microtubule binding Barwin PF00967.17 KXS13418.1 - 0.0062 16.4 0.6 0.012 15.5 0.6 1.4 1 0 0 1 1 1 1 Barwin family DUF3357 PF11837.8 KXS13418.1 - 0.064 13.7 3.8 0.11 12.9 3.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3357) DUF3040 PF11239.8 KXS13418.1 - 0.22 11.8 1.4 0.57 10.5 1.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) F-box-like PF12937.7 KXS13419.1 - 0.018 14.9 0.0 0.054 13.4 0.0 1.9 1 0 0 1 1 1 0 F-box-like F-box PF00646.33 KXS13419.1 - 0.15 11.9 0.0 0.15 11.9 0.0 2.6 3 0 0 3 3 3 0 F-box domain Nse5 PF08691.10 KXS13420.1 - 0.4 9.3 0.8 0.58 8.8 0.8 1.2 1 0 0 1 1 1 0 DNA repair proteins Nse5 and Nse6 F-box PF00646.33 KXS13422.1 - 1.1e-06 28.4 0.1 1.5e-06 27.9 0.1 1.3 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KXS13422.1 - 4.9e-06 26.3 0.0 7.4e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 KXS13422.1 - 0.00053 19.9 0.2 0.00075 19.4 0.2 1.2 1 0 0 1 1 1 1 F-box Helicase_C_4 PF13871.6 KXS13423.1 - 2.5e-18 66.7 0.1 3e-09 36.9 0.0 2.2 2 0 0 2 2 2 2 C-terminal domain on Strawberry notch homologue AAA_34 PF13872.6 KXS13423.1 - 1.5e-15 56.9 0.0 3.7e-13 49.0 0.0 2.3 1 1 1 2 2 2 2 P-loop containing NTP hydrolase pore-1 ADH_N_2 PF16884.5 KXS13424.1 - 6.4e-27 93.6 0.0 1.2e-26 92.7 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 KXS13424.1 - 1.1e-17 64.3 0.0 1.6e-17 63.7 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXS13424.1 - 6.1e-05 24.1 0.0 0.00012 23.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF2840 PF11000.8 KXS13425.1 - 0.076 12.8 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2840) DNA_pol_phi PF04931.13 KXS13425.1 - 0.49 8.4 5.2 0.58 8.2 5.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi SDA1 PF05285.12 KXS13425.1 - 1.2 8.5 9.1 1.5 8.2 9.1 1.1 1 0 0 1 1 1 0 SDA1 TPR_2 PF07719.17 KXS13426.1 - 1.1e-60 196.9 6.4 0.00027 20.8 0.0 20.8 21 1 0 21 21 20 12 Tetratricopeptide repeat TPR_1 PF00515.28 KXS13426.1 - 2.1e-52 172.9 10.3 0.00064 19.4 0.0 19.8 22 1 0 22 22 21 10 Tetratricopeptide repeat TPR_11 PF13414.6 KXS13426.1 - 2.6e-45 151.8 1.0 0.00022 20.9 0.0 14.4 13 1 1 14 14 14 9 TPR repeat TPR_17 PF13431.6 KXS13426.1 - 2.5e-38 127.7 1.1 0.059 13.8 0.0 17.3 17 1 1 18 18 17 7 Tetratricopeptide repeat TPR_9 PF13371.6 KXS13426.1 - 3.3e-38 129.7 32.4 7.6e-05 22.8 0.0 14.4 6 3 6 14 14 14 10 Tetratricopeptide repeat TPR_16 PF13432.6 KXS13426.1 - 1e-37 128.5 33.0 7.4e-07 29.7 1.0 14.5 9 3 8 17 17 17 11 Tetratricopeptide repeat TPR_19 PF14559.6 KXS13426.1 - 1e-26 93.2 9.5 0.023 15.2 0.1 11.2 10 1 2 12 12 12 7 Tetratricopeptide repeat TPR_8 PF13181.6 KXS13426.1 - 7.7e-26 88.1 0.1 2.4 8.6 0.0 15.0 16 0 0 16 16 15 4 Tetratricopeptide repeat TPR_12 PF13424.6 KXS13426.1 - 1.9e-21 76.1 12.0 0.0027 18.0 0.6 10.0 9 4 0 9 9 9 4 Tetratricopeptide repeat TPR_14 PF13428.6 KXS13426.1 - 5.3e-20 70.4 34.9 0.68 10.9 0.1 14.9 8 6 8 16 16 16 4 Tetratricopeptide repeat TPR_7 PF13176.6 KXS13426.1 - 3.6e-17 61.1 9.6 0.013 15.5 0.0 11.9 11 1 0 11 11 11 3 Tetratricopeptide repeat TPR_6 PF13174.6 KXS13426.1 - 1.6e-16 59.7 18.0 2.5 8.9 0.0 16.1 20 0 0 20 20 16 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KXS13426.1 - 2.2e-09 37.4 0.1 0.61 10.3 0.0 7.1 7 1 2 9 9 8 1 Anaphase-promoting complex, cyclosome, subunit 3 NARP1 PF12569.8 KXS13426.1 - 1.5e-07 30.7 0.5 0.52 9.2 0.0 6.8 7 2 2 9 9 9 1 NMDA receptor-regulated protein 1 TPR_MalT PF17874.1 KXS13426.1 - 0.0011 18.4 0.0 1.8 7.9 0.0 3.6 3 0 0 3 3 3 2 MalT-like TPR region BTAD PF03704.17 KXS13426.1 - 0.0046 17.4 15.4 0.037 14.5 0.4 5.4 5 1 0 5 5 5 1 Bacterial transcriptional activator domain TPR_10 PF13374.6 KXS13426.1 - 0.015 15.1 17.4 0.21 11.5 0.1 8.2 9 1 0 9 9 9 0 Tetratricopeptide repeat PPTA PF01239.22 KXS13426.1 - 0.028 14.2 3.0 9.4 6.1 0.0 4.2 4 0 0 4 4 4 0 Protein prenyltransferase alpha subunit repeat SHNi-TPR PF10516.9 KXS13426.1 - 0.039 13.4 14.3 2.3 7.7 0.0 7.2 9 0 0 9 9 9 0 SHNi-TPR Fis1_TPR_C PF14853.6 KXS13426.1 - 0.041 13.9 0.1 66 3.7 0.0 4.6 6 0 0 6 6 4 0 Fis1 C-terminal tetratricopeptide repeat DUF3808 PF10300.9 KXS13426.1 - 0.13 11.0 0.0 3 6.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3808) RibD_C PF01872.17 KXS13428.1 - 7.7e-18 65.0 0.0 3.6e-17 62.8 0.0 1.8 1 1 0 1 1 1 1 RibD C-terminal domain UvrA_inter PF17760.1 KXS13428.1 - 0.2 11.8 0.0 0.27 11.3 0.0 1.3 1 0 0 1 1 1 0 UvrA interaction domain STAS_2 PF13466.6 KXS13429.1 - 0.071 13.5 0.7 4.6 7.7 0.1 2.6 3 0 0 3 3 3 0 STAS domain DEAD PF00270.29 KXS13430.1 - 3.9e-43 147.3 0.0 6.6e-43 146.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXS13430.1 - 1.8e-23 83.0 0.0 2.2e-22 79.5 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.6 KXS13430.1 - 0.014 15.5 0.0 0.029 14.5 0.0 1.5 1 0 0 1 1 1 0 Helicase C-terminal domain UTP25 PF06862.12 KXS13430.1 - 0.24 10.1 0.0 12 4.5 0.0 2.2 2 0 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Nop14 PF04147.12 KXS13430.1 - 0.93 7.6 14.0 0.24 9.6 7.6 2.1 2 0 0 2 2 2 0 Nop14-like family Aldedh PF00171.22 KXS13431.1 - 1.2e-157 525.2 4.4 1.4e-157 525.0 4.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KXS13431.1 - 0.00035 20.1 0.0 0.0027 17.2 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) RRF PF01765.19 KXS13431.1 - 0.023 14.6 0.5 0.24 11.3 0.1 2.3 2 0 0 2 2 2 0 Ribosome recycling factor DUF2229 PF09989.9 KXS13431.1 - 0.17 11.5 0.2 0.31 10.7 0.2 1.3 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) adh_short PF00106.25 KXS13432.1 - 9.3e-42 142.7 6.5 2.2e-41 141.5 6.5 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXS13432.1 - 7e-40 137.0 6.3 1.3e-39 136.1 6.3 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXS13432.1 - 1.9e-09 37.7 2.5 3.3e-09 36.9 2.5 1.3 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KXS13432.1 - 0.0011 18.4 2.5 0.005 16.3 2.5 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 KXS13432.1 - 0.018 14.4 0.0 0.041 13.2 0.0 1.6 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) 3HCDH_N PF02737.18 KXS13432.1 - 0.09 12.7 1.9 0.16 11.8 1.9 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NmrA PF05368.13 KXS13432.1 - 0.2 11.2 2.3 0.31 10.6 2.3 1.3 1 0 0 1 1 1 0 NmrA-like family Ank_2 PF12796.7 KXS13433.1 - 5.4e-25 87.8 5.1 1.6e-16 60.7 3.0 3.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXS13433.1 - 1.8e-21 76.2 10.5 1.4e-10 41.4 0.1 4.4 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXS13433.1 - 1.9e-20 70.7 0.9 3.3e-06 27.0 0.0 5.7 5 0 0 5 5 5 4 Ankyrin repeat FYVE PF01363.21 KXS13433.1 - 5.5e-18 64.9 8.7 5.5e-18 64.9 8.7 2.6 2 0 0 2 2 2 1 FYVE zinc finger Ank_5 PF13857.6 KXS13433.1 - 1.3e-15 57.2 4.9 3.1e-07 30.5 0.9 5.2 3 1 3 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 KXS13433.1 - 1.2e-13 50.8 10.8 2.5e-05 24.5 0.1 4.9 4 0 0 4 4 4 4 Ankyrin repeat zf-RING_2 PF13639.6 KXS13433.1 - 2.4e-06 27.8 8.5 2.4e-06 27.8 8.5 3.5 3 0 0 3 3 2 1 Ring finger domain Pex24p PF06398.11 KXS13433.1 - 2.4e-06 26.8 1.2 4.3e-06 25.9 1.2 1.4 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin zf-RING_11 PF17123.5 KXS13433.1 - 3.9e-05 23.3 5.2 9.1e-05 22.1 5.2 1.7 1 0 0 1 1 1 1 RING-like zinc finger Zn_ribbon_17 PF17120.5 KXS13433.1 - 0.0033 17.0 6.2 0.0033 17.0 6.2 2.4 3 0 0 3 3 2 1 Zinc-ribbon, C4HC2 type zf-C3HC4_2 PF13923.6 KXS13433.1 - 0.0036 17.1 7.3 0.0036 17.1 7.3 3.5 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KXS13433.1 - 0.012 15.9 6.2 0.012 15.9 6.2 2.0 2 0 0 2 2 1 0 RING-H2 zinc finger domain FANCL_C PF11793.8 KXS13433.1 - 0.33 11.2 4.6 1 9.6 4.6 1.9 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING_9 PF13901.6 KXS13433.1 - 2.8 7.9 11.2 32 4.4 11.2 2.6 1 1 0 1 1 1 0 Putative zinc-RING and/or ribbon Methyltrn_RNA_4 PF09936.9 KXS13434.1 - 0.098 12.5 0.5 0.32 10.8 0.5 1.9 1 1 0 1 1 1 0 SAM-dependent RNA methyltransferase AA_permease_2 PF13520.6 KXS13435.1 - 2.4e-11 43.1 18.5 2.8e-11 42.9 18.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXS13435.1 - 0.002 16.8 14.2 0.0025 16.5 14.2 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KXS13436.1 - 1.6e-43 149.1 43.4 3.8e-43 147.9 43.4 1.5 1 1 0 1 1 1 1 Amino acid permease ABA_GPCR PF12430.8 KXS13438.1 - 7.8e-13 48.6 0.0 7.8e-13 48.6 0.0 2.3 2 1 0 2 2 2 1 Abscisic acid G-protein coupled receptor GPHR_N PF12537.8 KXS13438.1 - 2.7e-10 40.2 0.1 1.4e-09 37.9 0.0 2.2 2 0 0 2 2 2 1 The Golgi pH Regulator (GPHR) Family N-terminal S_4TM PF18159.1 KXS13438.1 - 2.2 7.5 0.0 2.2 7.5 0.0 2.5 2 1 0 2 2 2 0 SMODS-associating 4TM effector domain Rap_GAP PF02145.15 KXS13439.1 - 1.1e-40 139.2 0.0 2e-40 138.3 0.0 1.4 1 0 0 1 1 1 1 Rap/ran-GAP Lysine_decarbox PF03641.14 KXS13440.1 - 4.3e-32 111.0 0.0 8.5e-32 110.0 0.0 1.5 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 KXS13440.1 - 1.7e-13 50.4 0.0 3e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 SLOG cluster4 family Methyltransf_32 PF13679.6 KXS13441.1 - 3.5e-12 46.6 0.0 4.8e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXS13441.1 - 5.3e-05 23.1 0.1 0.00013 21.8 0.1 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXS13441.1 - 0.00058 19.7 0.0 0.0017 18.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 KXS13441.1 - 0.00086 18.9 0.1 0.0011 18.5 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 KXS13441.1 - 0.001 19.7 0.0 0.0019 18.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXS13441.1 - 0.0023 18.7 0.0 0.0039 17.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXS13441.1 - 0.0072 16.9 0.0 0.016 15.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 KXS13441.1 - 0.023 14.3 0.1 0.63 9.6 0.0 2.1 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW NodS PF05401.11 KXS13441.1 - 0.054 13.1 0.1 0.42 10.2 0.1 2.0 1 1 1 2 2 2 0 Nodulation protein S (NodS) TRM13 PF05206.14 KXS13441.1 - 0.071 12.6 0.0 0.095 12.2 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase TRM13 Trypsin_2 PF13365.6 KXS13443.1 - 7.7e-28 98.3 1.4 1.3e-27 97.6 1.4 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 KXS13443.1 - 6.1e-05 22.9 0.0 0.42 10.4 0.1 2.4 2 0 0 2 2 2 2 Trypsin Peptidase_S46 PF10459.9 KXS13443.1 - 0.0028 16.4 0.2 0.24 10.0 0.0 2.0 2 0 0 2 2 2 2 Peptidase S46 Peptidase_S29 PF02907.15 KXS13443.1 - 0.014 15.1 0.1 0.037 13.8 0.1 1.7 1 0 0 1 1 1 0 Hepatitis C virus NS3 protease QRPTase_C PF01729.19 KXS13444.1 - 2.2e-58 196.8 0.0 2.9e-58 196.4 0.0 1.2 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 KXS13444.1 - 6.4e-20 71.0 0.0 1.5e-19 69.9 0.0 1.6 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain TMP-TENI PF02581.17 KXS13444.1 - 0.035 13.5 0.0 0.061 12.6 0.0 1.4 1 0 0 1 1 1 0 Thiamine monophosphate synthase DUF2408 PF10303.9 KXS13445.1 - 2.1e-13 51.0 0.1 2.3e-06 28.2 0.0 2.8 1 1 1 2 2 2 2 Protein of unknown function (DUF2408) Ank_3 PF13606.6 KXS13447.1 - 0.00025 21.3 0.0 0.0086 16.5 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 KXS13447.1 - 0.0027 18.1 0.0 0.1 13.1 0.0 2.6 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 KXS13447.1 - 0.0069 16.7 0.0 0.034 14.5 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXS13447.1 - 0.0084 16.7 0.0 0.16 12.6 0.0 2.4 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXS13447.1 - 0.016 15.8 0.0 0.55 10.9 0.0 2.9 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Abhydrolase_1 PF00561.20 KXS13448.1 - 2.6e-21 76.4 0.1 1.5e-20 73.9 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXS13448.1 - 2.5e-14 53.2 0.0 2.6e-11 43.3 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KXS13448.1 - 1.4e-13 51.9 0.3 2.3e-13 51.3 0.3 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KXS13448.1 - 0.0011 18.4 0.1 1.1 8.7 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family DUF1749 PF08538.10 KXS13448.1 - 0.0075 15.4 0.0 0.024 13.7 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1749) Peptidase_S15 PF02129.18 KXS13448.1 - 0.022 14.3 0.1 3 7.4 0.0 2.2 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) ATG16 PF08614.11 KXS13449.1 - 3.7 7.7 0.0 3.7 7.7 0.0 2.7 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) CN_hydrolase PF00795.22 KXS13450.1 - 4.5e-07 29.5 0.0 8.2e-06 25.3 0.0 2.4 2 1 0 2 2 2 1 Carbon-nitrogen hydrolase Med13_C PF06333.12 KXS13450.1 - 0.045 13.0 0.0 0.067 12.5 0.0 1.2 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain HK97-gp10_like PF04883.12 KXS13450.1 - 0.21 12.6 0.4 14 6.8 0.0 2.7 3 0 0 3 3 3 0 Bacteriophage HK97-gp10, putative tail-component CitMHS PF03600.16 KXS13451.1 - 0.17 11.0 11.0 0.24 10.5 11.0 1.3 1 1 0 1 1 1 0 Citrate transporter GST_N_3 PF13417.6 KXS13452.1 - 2e-10 40.9 0.0 3.6e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KXS13452.1 - 7.8e-08 32.6 0.0 1.4e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KXS13452.1 - 7.2e-06 26.1 0.1 1.3e-05 25.3 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KXS13452.1 - 7.2e-06 26.2 0.0 6.9e-05 23.1 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KXS13452.1 - 0.00012 22.2 0.0 0.00023 21.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 KXS13452.1 - 0.00015 22.4 0.0 0.00054 20.6 0.0 2.0 2 1 0 2 2 2 1 Glutathione S-transferase N-terminal domain GST_C_2 PF13410.6 KXS13452.1 - 0.00017 21.6 0.6 0.00036 20.5 0.6 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Cys_Met_Meta_PP PF01053.20 KXS13453.1 - 1.2e-60 205.1 0.0 3e-60 203.8 0.0 1.6 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DUF423 PF04241.15 KXS13454.1 - 0.13 12.4 0.4 0.13 12.4 0.4 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF423) DUF3835 PF12927.7 KXS13455.1 - 0.002 19.0 8.4 0.23 12.3 1.0 3.9 3 0 0 3 3 3 2 Domain of unknown function (DUF3835) Aldose_epim PF01263.20 KXS13456.1 - 3.4e-33 115.2 0.0 5e-33 114.7 0.0 1.3 1 0 0 1 1 1 1 Aldose 1-epimerase iPGM_N PF06415.13 KXS13457.1 - 9.7e-75 250.7 0.0 1.3e-74 250.3 0.0 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Metalloenzyme PF01676.18 KXS13457.1 - 1.3e-74 250.7 0.0 1.5e-74 250.5 0.0 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 KXS13457.1 - 1.5e-06 27.8 0.0 3.7e-06 26.6 0.0 1.8 2 1 0 2 2 2 1 Sulfatase Phosphodiest PF01663.22 KXS13457.1 - 1.8e-06 27.8 0.1 3.2e-06 27.0 0.1 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase PBP1_TM PF14812.6 KXS13459.1 - 0.65 10.4 6.9 2.2 8.7 2.5 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal AF-4 PF05110.13 KXS13459.1 - 0.96 7.5 19.0 1.2 7.2 19.0 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein F-box-like PF12937.7 KXS13460.1 - 0.0048 16.8 0.4 0.011 15.6 0.2 1.7 2 0 0 2 2 2 1 F-box-like CorA PF01544.18 KXS13461.1 - 1.4e-38 132.9 0.1 2.7e-36 125.4 0.0 2.2 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein MFS_1 PF07690.16 KXS13462.1 - 2.1e-22 79.6 36.5 2.4e-22 79.3 26.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily CitMHS PF03600.16 KXS13462.1 - 0.11 11.7 11.6 0.87 8.7 0.9 2.4 2 1 0 2 2 2 0 Citrate transporter MIP PF00230.20 KXS13463.1 - 3.2e-48 164.4 13.3 3.6e-48 164.3 13.3 1.0 1 0 0 1 1 1 1 Major intrinsic protein SWIB PF02201.18 KXS13464.1 - 1.5e-24 85.6 0.0 2.9e-24 84.8 0.0 1.5 1 0 0 1 1 1 1 SWIB/MDM2 domain DEK_C PF08766.11 KXS13464.1 - 5e-11 42.4 0.9 5e-11 42.4 0.9 1.9 3 0 0 3 3 3 1 DEK C terminal domain DUF2201_N PF13203.6 KXS13464.1 - 0.0061 16.2 0.0 0.013 15.1 0.0 1.5 1 1 1 2 2 2 1 Putative metallopeptidase domain LRR_4 PF12799.7 KXS13466.1 - 1.2e-10 41.4 16.7 7.1e-05 23.1 2.9 3.2 1 1 4 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXS13466.1 - 1.2e-07 31.4 12.9 7.3e-05 22.5 1.6 2.6 1 1 2 3 3 3 3 Leucine rich repeat LRR_1 PF00560.33 KXS13466.1 - 0.0071 16.7 4.3 21 6.2 0.0 5.0 3 2 1 4 4 4 1 Leucine Rich Repeat LRR_6 PF13516.6 KXS13466.1 - 0.8 9.9 5.2 5 7.4 0.1 3.5 3 0 0 3 3 3 0 Leucine Rich repeat Ssu72 PF04722.13 KXS13467.1 - 3.1e-82 274.8 0.0 3.5e-82 274.6 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein DUF1794 PF08768.11 KXS13468.1 - 7.5e-34 116.8 0.0 9.5e-34 116.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1794) AAA_5 PF07728.14 KXS13469.1 - 1.4e-83 277.8 0.0 2.1e-28 99.1 0.0 4.7 3 1 0 3 3 3 3 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KXS13469.1 - 4e-08 33.8 1.3 0.12 12.8 0.0 4.9 3 2 2 5 5 5 2 AAA ATPase domain AAA_22 PF13401.6 KXS13469.1 - 1.9e-05 25.0 0.1 0.45 10.8 0.0 4.0 2 1 0 2 2 2 2 AAA domain CbbQ_C PF08406.10 KXS13469.1 - 0.00012 22.3 0.1 0.029 14.6 0.0 2.8 2 0 0 2 2 2 1 CbbQ/NirQ/NorQ C-terminal ABC_tran PF00005.27 KXS13469.1 - 0.0002 21.9 0.0 0.67 10.5 0.0 2.7 2 0 0 2 2 2 2 ABC transporter Mg_chelatase PF01078.21 KXS13469.1 - 0.0014 18.0 0.1 3.8 6.8 0.0 3.5 3 1 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_29 PF13555.6 KXS13469.1 - 0.0016 18.1 0.0 0.31 10.8 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_lid_7 PF17867.1 KXS13469.1 - 0.0017 18.5 0.1 0.078 13.2 0.0 2.5 2 0 0 2 2 2 1 Midasin AAA lid domain AAA_7 PF12775.7 KXS13469.1 - 0.0067 16.0 0.0 2.6 7.5 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region Roc PF08477.13 KXS13469.1 - 0.025 14.8 0.0 4.3 7.6 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_30 PF13604.6 KXS13469.1 - 0.034 13.9 0.3 0.3 10.8 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KXS13469.1 - 0.047 13.9 0.8 1 9.6 0.0 3.2 4 0 0 4 4 4 0 AAA domain AAA_14 PF13173.6 KXS13469.1 - 0.063 13.3 0.0 4.4 7.3 0.0 3.0 3 0 0 3 3 3 0 AAA domain TniB PF05621.11 KXS13469.1 - 0.081 12.3 0.0 11 5.4 0.0 3.0 3 0 0 3 3 3 0 Bacterial TniB protein FtsK_SpoIIIE PF01580.18 KXS13469.1 - 0.092 12.1 0.0 0.51 9.7 0.0 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_33 PF13671.6 KXS13469.1 - 0.11 12.7 0.0 1.3 9.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KXS13469.1 - 0.14 12.7 0.0 1.3 9.5 0.0 2.7 3 0 0 3 3 2 0 AAA domain RNA_helicase PF00910.22 KXS13469.1 - 0.18 12.2 0.0 3.1 8.2 0.0 2.4 2 0 0 2 2 2 0 RNA helicase EGF_alliinase PF04863.13 KXS13469.1 - 0.19 12.1 0.0 0.51 10.8 0.0 1.7 1 0 0 1 1 1 0 Alliinase EGF-like domain BioY PF02632.14 KXS13470.1 - 0.026 14.6 0.3 0.026 14.6 0.3 3.0 2 1 1 3 3 3 0 BioY family Glyco_hydro_47 PF01532.20 KXS13471.1 - 1.9e-84 284.2 0.0 2.8e-84 283.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 RNR_Alpha PF17975.1 KXS13471.1 - 0.023 15.2 0.4 0.045 14.3 0.4 1.4 1 0 0 1 1 1 0 Ribonucleotide reductase alpha domain GH-E PF14410.6 KXS13472.1 - 0.071 13.5 0.1 0.15 12.5 0.1 1.5 1 0 0 1 1 1 0 HNH/ENDO VII superfamily nuclease with conserved GHE residues FMO-like PF00743.19 KXS13473.1 - 4.1e-10 38.7 0.0 6.5e-09 34.7 0.0 2.1 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KXS13473.1 - 1.1e-09 37.9 0.0 1.5e-08 34.2 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXS13473.1 - 4e-08 32.8 0.0 1.4e-07 31.0 0.0 1.8 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KXS13473.1 - 9.4e-08 32.2 0.0 4e-07 30.1 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KXS13473.1 - 1.6e-07 30.9 0.0 2.6e-06 26.9 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXS13473.1 - 0.0043 16.3 0.0 0.8 8.9 0.0 2.4 2 0 0 2 2 2 2 Thi4 family Pyr_redox PF00070.27 KXS13473.1 - 0.01 16.4 0.0 7.7 7.2 0.0 2.8 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXS13473.1 - 0.03 13.0 0.0 14 4.3 0.0 2.9 3 0 0 3 3 3 0 HI0933-like protein NAD_binding_9 PF13454.6 KXS13473.1 - 0.032 14.2 0.1 6.2 6.8 0.0 3.4 4 0 0 4 4 4 0 FAD-NAD(P)-binding NAD_binding_7 PF13241.6 KXS13473.1 - 0.039 14.4 0.0 0.13 12.7 0.0 2.0 2 0 0 2 2 1 0 Putative NAD(P)-binding Shikimate_DH PF01488.20 KXS13473.1 - 0.1 12.7 0.0 0.66 10.0 0.0 2.1 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase AlaDh_PNT_C PF01262.21 KXS13473.1 - 0.11 11.8 0.0 2.3 7.4 0.0 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain DUF5496 PF17600.2 KXS13473.1 - 0.19 11.8 0.0 0.47 10.5 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5496) Asp PF00026.23 KXS13474.1 - 7.2e-72 242.5 4.4 1.2e-71 241.8 4.4 1.3 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KXS13474.1 - 2.7e-11 44.0 1.2 1.6e-10 41.5 1.2 2.1 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 KXS13474.1 - 7.6e-05 22.5 0.0 0.00034 20.4 0.0 2.1 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal Glyco_hydro_26 PF02156.15 KXS13475.1 - 8.6e-07 28.7 7.7 5.7e-05 22.7 7.7 2.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 26 Bromodomain PF00439.25 KXS13476.1 - 5.9e-18 64.7 0.1 1.2e-17 63.8 0.1 1.5 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 KXS13476.1 - 6.1e-09 36.1 0.1 1.5e-08 34.9 0.1 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXS13476.1 - 4.1e-06 26.7 0.0 7.5e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXS13476.1 - 0.0004 20.8 0.2 0.00091 19.6 0.2 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Ribosomal_L7Ae PF01248.26 KXS13477.1 - 3e-24 84.5 0.0 3.5e-24 84.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Cyto_heme_lyase PF01265.17 KXS13478.1 - 1.3e-70 238.3 6.7 1.8e-69 234.6 6.7 2.1 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase RNase_PH PF01138.21 KXS13479.1 - 3.3e-26 92.3 0.0 5.1e-26 91.7 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KXS13479.1 - 1.1e-07 31.8 0.0 2e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 PP2C PF00481.21 KXS13480.1 - 2.2e-14 53.7 0.0 4.4e-12 46.2 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C Cript PF10235.9 KXS13481.1 - 5.7e-28 97.3 6.0 5.7e-28 97.3 6.0 1.5 1 1 1 2 2 2 1 Microtubule-associated protein CRIPT DZR PF12773.7 KXS13481.1 - 0.0048 16.9 9.6 0.0084 16.1 6.0 2.2 1 1 1 2 2 2 1 Double zinc ribbon DUF2039 PF10217.9 KXS13481.1 - 0.015 15.6 7.5 0.015 15.6 7.5 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) zinc_ribbon_2 PF13240.6 KXS13481.1 - 0.02 14.6 10.2 0.56 10.0 4.2 3.2 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_15 PF17032.5 KXS13481.1 - 0.06 14.1 11.3 0.17 12.7 7.9 2.6 2 1 0 2 2 2 0 zinc-ribbon family Cytochrom_c3_2 PF14537.6 KXS13481.1 - 0.64 10.5 9.4 0.18 12.3 6.2 1.9 2 1 0 2 2 2 0 Cytochrome c3 Fer2 PF00111.27 KXS13481.1 - 0.79 9.7 10.3 2 8.4 1.7 3.0 2 1 1 3 3 3 0 2Fe-2S iron-sulfur cluster binding domain zf-dskA_traR PF01258.17 KXS13481.1 - 2.2 8.3 0.1 2.2 8.3 0.1 3.5 3 1 1 4 4 4 0 Prokaryotic dksA/traR C4-type zinc finger RTTN_N PF14726.6 KXS13483.1 - 2.2e-07 31.6 0.1 2.8e-06 28.0 0.1 2.5 1 1 0 1 1 1 1 Rotatin, an armadillo repeat protein, centriole functioning Sde2_N_Ubi PF13019.6 KXS13484.1 - 1e-23 84.0 1.1 1.4e-23 83.5 1.1 1.4 1 1 0 1 1 1 1 Silencing defective 2 N-terminal ubiquitin domain CUE PF02845.16 KXS13485.1 - 8.9e-10 38.1 0.9 1.8e-09 37.1 0.3 1.9 2 0 0 2 2 2 1 CUE domain TMA7 PF09072.10 KXS13485.1 - 1.7 9.5 7.2 13 6.7 0.8 2.3 2 0 0 2 2 2 0 Translation machinery associated TMA7 Y_phosphatase2 PF03162.13 KXS13486.1 - 2.5e-31 108.5 0.0 3.1e-31 108.2 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family AAA PF00004.29 KXS13487.1 - 1.6e-42 145.1 0.0 2.6e-42 144.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KXS13487.1 - 1.4e-13 50.4 0.1 2.8e-13 49.4 0.1 1.5 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 KXS13487.1 - 1.5e-09 37.6 1.0 2.5e-09 37.0 0.1 1.9 2 0 0 2 2 1 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 KXS13487.1 - 1.7e-07 31.3 0.1 2.4e-06 27.6 0.0 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KXS13487.1 - 1.6e-06 28.6 0.1 0.00064 20.1 0.1 2.8 2 1 1 3 3 3 1 AAA ATPase domain AAA_2 PF07724.14 KXS13487.1 - 5.6e-06 26.6 0.0 1.4e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 KXS13487.1 - 1.6e-05 24.7 0.0 3.6e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KXS13487.1 - 0.00017 21.8 0.1 0.0049 17.2 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KXS13487.1 - 0.00058 20.4 0.0 0.0018 18.8 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KXS13487.1 - 0.0019 17.7 0.0 0.0037 16.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region DUF815 PF05673.13 KXS13487.1 - 0.0022 17.2 0.0 0.0051 16.0 0.0 1.6 2 0 0 2 2 1 1 Protein of unknown function (DUF815) AAA_33 PF13671.6 KXS13487.1 - 0.0039 17.3 0.0 0.011 15.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 KXS13487.1 - 0.0041 16.5 0.0 0.0083 15.5 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TsaE PF02367.17 KXS13487.1 - 0.0054 16.7 0.0 0.0097 15.9 0.0 1.3 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Thymidylate_kin PF02223.17 KXS13487.1 - 0.006 16.3 0.1 3.1 7.4 0.0 2.6 2 1 0 2 2 2 1 Thymidylate kinase TIP49 PF06068.13 KXS13487.1 - 0.009 15.3 0.0 0.017 14.4 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_3 PF07726.11 KXS13487.1 - 0.0094 15.8 0.0 0.021 14.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KXS13487.1 - 0.013 15.2 0.0 0.028 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KXS13487.1 - 0.015 15.1 0.0 0.028 14.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Sigma54_activat PF00158.26 KXS13487.1 - 0.021 14.5 0.0 0.099 12.3 0.0 2.1 1 1 0 1 1 1 0 Sigma-54 interaction domain RNA_helicase PF00910.22 KXS13487.1 - 0.028 14.8 0.0 0.056 13.8 0.0 1.5 1 0 0 1 1 1 0 RNA helicase ATPase PF06745.13 KXS13487.1 - 0.037 13.4 1.1 0.16 11.3 0.0 2.4 3 0 0 3 3 3 0 KaiC AAA_28 PF13521.6 KXS13487.1 - 0.04 14.2 0.1 0.093 13.0 0.0 1.7 2 0 0 2 2 1 0 AAA domain PhoH PF02562.16 KXS13487.1 - 0.044 13.2 0.0 0.082 12.3 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_14 PF13173.6 KXS13487.1 - 0.05 13.6 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KXS13487.1 - 0.075 12.6 0.1 0.22 11.1 0.1 1.7 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 KXS13487.1 - 0.077 12.1 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NACHT PF05729.12 KXS13487.1 - 0.12 12.3 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_30 PF13604.6 KXS13487.1 - 0.13 12.0 0.1 0.35 10.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain SSB PF00436.25 KXS13488.1 - 8.1e-15 54.7 0.2 1e-14 54.4 0.2 1.1 1 0 0 1 1 1 1 Single-strand binding protein family DUF4131 PF13567.6 KXS13488.1 - 0.036 13.7 0.0 0.049 13.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF3672 PF12421.8 KXS13488.1 - 0.13 12.1 0.0 0.27 11.2 0.0 1.5 2 0 0 2 2 2 0 Fibronectin type III protein ATP-synt_C PF00137.21 KXS13489.1 - 2.3e-32 111.1 33.7 1.4e-19 70.2 11.4 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Transket_pyr PF02779.24 KXS13490.1 - 3.3e-46 157.2 0.1 6.6e-46 156.2 0.1 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KXS13490.1 - 7.4e-41 138.9 0.1 1.4e-40 138.0 0.1 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain PFOR_II PF17147.4 KXS13490.1 - 0.022 15.1 0.0 0.068 13.5 0.0 1.8 2 0 0 2 2 2 0 Pyruvate:ferredoxin oxidoreductase core domain II Coatomer_WDAD PF04053.14 KXS13491.1 - 3.5e-168 560.3 0.0 2.2e-166 554.3 0.0 2.2 2 0 0 2 2 2 2 Coatomer WD associated region WD40 PF00400.32 KXS13491.1 - 6.7e-41 137.5 4.5 5.8e-07 30.1 0.0 7.9 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXS13491.1 - 2.1e-08 34.3 0.1 0.37 11.1 0.0 6.1 3 2 3 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KXS13491.1 - 0.05 12.2 2.5 1.5 7.4 0.0 3.2 2 2 1 3 3 3 0 Nucleoporin Nup120/160 SPC22 PF04573.12 KXS13492.1 - 4e-50 169.6 0.0 4.5e-50 169.5 0.0 1.0 1 0 0 1 1 1 1 Signal peptidase subunit PARG_cat PF05028.14 KXS13493.1 - 8.5e-89 298.2 0.0 1.3e-88 297.6 0.0 1.2 1 0 0 1 1 1 1 Poly (ADP-ribose) glycohydrolase (PARG) HTH_28 PF13518.6 KXS13493.1 - 0.13 12.4 0.0 0.34 11.1 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain IDO PF01231.18 KXS13494.1 - 2.4e-76 257.3 0.0 4.6e-76 256.4 0.0 1.4 1 1 0 1 1 1 1 Indoleamine 2,3-dioxygenase MaoC_dehydratas PF01575.19 KXS13495.1 - 6.9e-28 96.7 0.0 1.1e-27 96.1 0.0 1.2 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 KXS13495.1 - 6.6e-08 32.8 0.0 5e-06 26.7 0.0 2.2 2 0 0 2 2 2 2 N-terminal half of MaoC dehydratase Pkinase PF00069.25 KXS13496.1 - 2.6e-54 184.4 0.0 3.8e-54 183.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS13496.1 - 2e-28 99.4 0.0 3e-28 98.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXS13496.1 - 0.0031 16.9 0.0 0.0067 15.8 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 KXS13496.1 - 0.014 15.3 0.0 0.35 10.7 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 KXS13496.1 - 0.19 11.1 0.0 0.31 10.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ArfGap PF01412.18 KXS13497.1 - 1.3e-36 125.2 0.1 2.7e-36 124.2 0.1 1.6 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf BAR_3 PF16746.5 KXS13497.1 - 1.5e-18 67.4 0.8 6.6e-18 65.3 0.8 1.8 1 1 0 1 1 1 1 BAR domain of APPL family Ank_4 PF13637.6 KXS13497.1 - 3.1e-11 43.6 0.2 1.7e-06 28.4 0.0 3.9 3 0 0 3 3 3 2 Ankyrin repeats (many copies) PH PF00169.29 KXS13497.1 - 8.3e-10 39.1 0.0 2.2e-09 37.8 0.0 1.8 1 0 0 1 1 1 1 PH domain Ank_3 PF13606.6 KXS13497.1 - 5.7e-07 29.3 0.1 0.0011 19.3 0.0 3.7 2 1 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 KXS13497.1 - 2e-06 28.0 0.1 0.016 15.6 0.1 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 KXS13497.1 - 7.1e-06 26.2 1.0 0.0021 18.4 0.1 3.4 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXS13497.1 - 0.00017 22.1 0.1 0.0043 17.6 0.1 2.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) IMD PF08397.11 KXS13497.1 - 0.0051 16.2 0.4 0.012 15.0 0.2 1.7 1 1 1 2 2 2 1 IRSp53/MIM homology domain SOG2 PF10428.9 KXS13497.1 - 0.99 8.5 16.0 2.2 7.4 16.0 1.5 1 0 0 1 1 1 0 RAM signalling pathway protein Sec1 PF00995.23 KXS13498.1 - 9.8e-124 414.7 0.0 1.2e-123 414.4 0.0 1.1 1 0 0 1 1 1 1 Sec1 family OSCP PF00213.18 KXS13498.1 - 0.029 14.5 0.9 0.069 13.3 0.4 1.9 2 0 0 2 2 2 0 ATP synthase delta (OSCP) subunit PDGF_N PF04692.13 KXS13498.1 - 0.73 10.7 2.7 68 4.3 0.1 3.4 3 1 1 4 4 4 0 Platelet-derived growth factor, N terminal region L27 PF02828.16 KXS13498.1 - 0.9 9.3 5.4 2.5 7.9 0.3 2.9 3 0 0 3 3 3 0 L27 domain PP2C PF00481.21 KXS13500.1 - 1.8e-63 214.6 0.0 8.5e-62 209.1 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.12 KXS13500.1 - 0.0071 16.3 0.1 0.14 12.0 0.1 2.3 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) LRR_4 PF12799.7 KXS13501.1 - 0.01 16.2 6.1 0.4 11.2 1.1 4.1 4 1 0 5 5 5 0 Leucine Rich repeats (2 copies) DHBP_synthase PF00926.19 KXS13501.1 - 0.11 12.1 0.0 7 6.1 0.0 2.2 2 0 0 2 2 2 0 3,4-dihydroxy-2-butanone 4-phosphate synthase Lact-deh-memb PF09330.11 KXS13501.1 - 0.22 10.8 0.0 0.41 10.0 0.0 1.3 1 0 0 1 1 1 0 D-lactate dehydrogenase, membrane binding LRR_1 PF00560.33 KXS13501.1 - 1.1 10.0 3.0 19 6.3 0.1 3.6 4 0 0 4 4 4 0 Leucine Rich Repeat zf-MYND PF01753.18 KXS13502.1 - 1.2e-08 34.8 11.8 1.2e-08 34.8 11.8 2.2 2 0 0 2 2 2 1 MYND finger SET PF00856.28 KXS13503.1 - 0.0032 17.9 0.1 0.0041 17.5 0.1 1.4 1 1 0 1 1 1 1 SET domain FeThRed_A PF02941.15 KXS13503.1 - 0.14 12.3 0.0 7 6.9 0.0 2.2 2 0 0 2 2 2 0 Ferredoxin thioredoxin reductase variable alpha chain EB PF01683.18 KXS13504.1 - 0.00012 22.3 61.8 0.11 12.8 7.2 6.4 4 4 2 6 6 6 4 EB module Gram_pos_anchor PF00746.21 KXS13504.1 - 0.0065 16.4 0.4 0.0065 16.4 0.4 2.1 2 0 0 2 2 2 1 LPXTG cell wall anchor motif Podoplanin PF05808.11 KXS13504.1 - 0.02 15.0 0.2 0.042 13.9 0.2 1.5 1 0 0 1 1 1 0 Podoplanin Yip1 PF04893.17 KXS13504.1 - 0.061 13.0 0.0 0.096 12.4 0.0 1.3 1 0 0 1 1 1 0 Yip1 domain DUF3042 PF11240.8 KXS13504.1 - 0.15 12.1 0.5 0.33 11.0 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3042) DUF202 PF02656.15 KXS13504.1 - 1 9.9 4.0 0.45 11.0 1.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF202) Ribosomal_L36e PF01158.18 KXS13505.1 - 1.5e-41 140.6 7.4 1.7e-41 140.4 7.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e TetR_C_9 PF14514.6 KXS13505.1 - 0.0079 16.3 0.2 0.0098 16.0 0.2 1.1 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain LemA PF04011.12 KXS13505.1 - 0.014 15.2 0.7 0.019 14.8 0.7 1.2 1 0 0 1 1 1 0 LemA family 4HB_MCP_1 PF12729.7 KXS13505.1 - 0.029 13.9 0.2 0.036 13.6 0.2 1.1 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction PBS_linker_poly PF00427.21 KXS13505.1 - 0.06 13.4 0.2 0.069 13.2 0.2 1.1 1 0 0 1 1 1 0 Phycobilisome Linker polypeptide DUF2207 PF09972.9 KXS13505.1 - 0.089 11.5 0.1 0.1 11.3 0.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) zf-CCCH PF00642.24 KXS13506.1 - 7.2e-12 44.9 13.5 6.4e-07 29.1 5.0 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 KXS13506.1 - 1.4e-10 41.8 2.0 6.5e-06 26.8 0.1 2.3 2 0 0 2 2 2 2 Torus domain zf_CCCH_4 PF18345.1 KXS13506.1 - 8.1e-10 38.4 19.0 2.8e-05 24.0 5.1 2.3 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 KXS13506.1 - 1.2e-07 31.4 16.9 0.00059 19.6 3.6 2.3 2 0 0 2 2 2 2 CCCH-type zinc finger zf-CCCH_2 PF14608.6 KXS13506.1 - 0.0036 17.7 11.0 0.021 15.3 2.1 2.4 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 KXS13506.1 - 4.2 7.6 5.9 8.5 6.6 0.3 2.3 2 0 0 2 2 2 0 Zinc-finger containing family PMT PF02366.18 KXS13508.1 - 2.3e-87 292.7 17.5 2.3e-87 292.7 17.5 1.9 3 0 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 KXS13508.1 - 1.8e-55 187.6 4.0 1.8e-55 187.6 4.0 2.7 2 0 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 KXS13508.1 - 5.5e-23 81.8 0.3 5.4e-16 59.0 0.2 2.4 2 0 0 2 2 2 2 MIR domain Cyclin_N PF00134.23 KXS13509.1 - 3.4e-35 120.6 0.2 7.4e-35 119.5 0.1 1.6 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KXS13509.1 - 6.8e-22 77.8 0.0 1.5e-21 76.7 0.0 1.6 2 0 0 2 2 2 1 Cyclin, C-terminal domain JmjC PF02373.22 KXS13510.1 - 1.6e-39 134.8 0.8 4e-39 133.6 0.4 1.9 2 0 0 2 2 2 1 JmjC domain, hydroxylase ARID PF01388.21 KXS13510.1 - 2.7e-17 63.2 0.0 4.9e-17 62.4 0.0 1.5 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain JmjN PF02375.17 KXS13510.1 - 6.3e-15 54.8 1.6 8.8e-15 54.4 0.7 1.8 2 0 0 2 2 2 1 jmjN domain zf-C5HC2 PF02928.16 KXS13510.1 - 1.4e-06 28.6 14.3 0.00092 19.6 2.1 2.7 2 0 0 2 2 2 2 C5HC2 zinc finger PHD PF00628.29 KXS13510.1 - 3.7e-06 26.7 4.1 3.7e-06 26.7 4.1 2.9 3 0 0 3 3 3 1 PHD-finger PHD_2 PF13831.6 KXS13510.1 - 0.0003 20.3 3.7 0.0012 18.4 3.7 2.1 1 0 0 1 1 1 1 PHD-finger zf-PHD-like PF15446.6 KXS13510.1 - 0.0033 17.0 0.5 0.0073 15.9 0.5 1.6 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain DUF3079 PF11278.8 KXS13510.1 - 0.0081 16.0 1.8 0.03 14.1 1.8 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3079) C1_1 PF00130.22 KXS13510.1 - 0.021 14.7 0.2 0.021 14.7 0.2 2.4 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.6 KXS13510.1 - 9.7 6.2 11.0 0.43 10.5 1.8 2.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 PIF1 PF05970.14 KXS13512.1 - 1.4e-25 90.3 4.8 2.6e-09 36.8 0.0 5.0 3 2 2 5 5 5 4 PIF1-like helicase AAA_30 PF13604.6 KXS13512.1 - 2.6e-09 37.1 0.1 0.19 11.4 0.0 4.2 3 1 1 4 4 4 3 AAA domain AAA_16 PF13191.6 KXS13512.1 - 0.00025 21.5 0.0 0.00049 20.5 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 KXS13512.1 - 0.0052 16.3 0.0 0.009 15.5 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_32 PF13654.6 KXS13512.1 - 0.0065 15.3 0.0 0.0096 14.7 0.0 1.1 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 KXS13512.1 - 0.0071 16.3 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 NTPase AAA_22 PF13401.6 KXS13512.1 - 0.0077 16.5 0.2 0.023 15.0 0.2 1.8 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KXS13512.1 - 0.0087 15.8 0.1 0.12 12.1 0.0 2.1 1 1 1 2 2 2 1 IstB-like ATP binding protein PhoH PF02562.16 KXS13512.1 - 0.033 13.6 0.0 0.055 12.9 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein Mg_chelatase PF01078.21 KXS13512.1 - 0.063 12.7 0.0 0.17 11.2 0.0 1.5 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 KXS13512.1 - 0.088 12.0 0.1 0.15 11.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ATPase_2 PF01637.18 KXS13512.1 - 0.11 12.3 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_33 PF13671.6 KXS13512.1 - 0.16 12.1 0.6 1.3 9.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 KXS13512.1 - 0.16 11.1 0.0 0.3 10.2 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Orn_Arg_deC_N PF02784.16 KXS13513.1 - 5.6e-42 143.8 0.0 8.9e-42 143.2 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Arg_decarb_HB PF17810.1 KXS13513.1 - 7.3e-17 61.4 0.0 1.4e-16 60.5 0.0 1.5 1 0 0 1 1 1 1 Arginine decarboxylase helical bundle domain Arg_decarbox_C PF17944.1 KXS13513.1 - 4.4e-12 46.4 0.0 9.7e-12 45.3 0.0 1.6 1 0 0 1 1 1 1 Arginine decarboxylase C-terminal helical extension CENP-T_C PF15511.6 KXS13514.1 - 4.7e-08 33.1 0.1 5.7e-08 32.8 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 KXS13514.1 - 8.4e-05 22.7 0.1 0.00012 22.1 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 KXS13514.1 - 0.00016 22.0 0.1 0.00021 21.6 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 KXS13514.1 - 0.0013 18.9 0.1 0.0025 18.0 0.0 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KXS13514.1 - 0.002 18.5 0.1 0.0023 18.3 0.1 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KXS13514.1 - 0.036 14.1 0.0 0.04 14.0 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Histone PF00125.24 KXS13515.1 - 3.2e-52 176.4 2.7 3.5e-52 176.2 2.7 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 KXS13515.1 - 2.3e-05 24.7 0.0 3.5e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 KXS13515.1 - 3e-05 24.1 0.4 4.8e-05 23.4 0.1 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 KXS13515.1 - 0.00018 22.1 1.1 0.00021 21.9 1.1 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 KXS13515.1 - 0.0057 16.9 0.0 0.011 16.0 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KXS13515.1 - 0.057 13.5 0.1 0.11 12.6 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KXS13515.1 - 0.1 12.6 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated Flagellin_N PF00669.20 KXS13517.1 - 0.028 14.5 0.2 0.082 13.0 0.2 1.8 1 0 0 1 1 1 0 Bacterial flagellin N-terminal helical region Histone PF00125.24 KXS13518.1 - 3.2e-52 176.4 2.7 3.5e-52 176.2 2.7 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 KXS13518.1 - 2.3e-05 24.7 0.0 3.5e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 KXS13518.1 - 3e-05 24.1 0.4 4.8e-05 23.4 0.1 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 KXS13518.1 - 0.00018 22.1 1.1 0.00021 21.9 1.1 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 KXS13518.1 - 0.0057 16.9 0.0 0.011 16.0 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KXS13518.1 - 0.057 13.5 0.1 0.11 12.6 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KXS13518.1 - 0.1 12.6 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated CENP-T_C PF15511.6 KXS13519.1 - 4.7e-08 33.1 0.1 5.7e-08 32.8 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 KXS13519.1 - 8.4e-05 22.7 0.1 0.00012 22.1 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 KXS13519.1 - 0.00016 22.0 0.1 0.00021 21.6 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 KXS13519.1 - 0.0013 18.9 0.1 0.0025 18.0 0.0 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KXS13519.1 - 0.002 18.5 0.1 0.0023 18.3 0.1 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KXS13519.1 - 0.036 14.1 0.0 0.04 14.0 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit FmdA_AmdA PF03069.15 KXS13520.1 - 6.5e-104 347.7 0.0 7.7e-104 347.5 0.0 1.1 1 0 0 1 1 1 1 Acetamidase/Formamidase family DNA_pol_E_B PF04042.16 KXS13522.1 - 8.7e-36 123.2 0.0 1.1e-35 122.9 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Pol_alpha_B_N PF08418.10 KXS13522.1 - 0.00074 19.6 0.0 0.0012 18.9 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal Pol_alpha_B_N PF08418.10 KXS13523.1 - 5e-09 36.5 0.0 5.6e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal Glyco_transf_22 PF03901.17 KXS13524.1 - 6.6e-79 266.1 13.3 7.8e-79 265.8 13.3 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Peptidase_S24 PF00717.23 KXS13525.1 - 9.8e-11 41.5 0.1 2.2e-10 40.3 0.1 1.7 1 1 0 1 1 1 1 Peptidase S24-like TerC PF03741.16 KXS13525.1 - 0.036 13.7 1.0 0.12 12.1 0.1 1.9 2 0 0 2 2 2 0 Integral membrane protein TerC family Pam16 PF03656.13 KXS13526.1 - 3.8e-05 23.7 0.0 4.2e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Pam16 DnaJ PF00226.31 KXS13526.1 - 5.8e-05 23.1 0.3 0.00012 22.1 0.0 1.7 2 0 0 2 2 2 1 DnaJ domain DUF4083 PF13314.6 KXS13526.1 - 0.14 12.2 0.0 0.34 10.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) zf-RanBP PF00641.18 KXS13527.1 - 2.8e-22 77.7 31.2 4.2e-08 32.3 5.5 3.4 3 0 0 3 3 3 3 Zn-finger in Ran binding protein and others DZR PF12773.7 KXS13527.1 - 0.02 14.9 17.6 0.24 11.5 9.5 2.8 2 1 1 3 3 3 0 Double zinc ribbon zf-Sec23_Sec24 PF04810.15 KXS13527.1 - 0.32 11.1 10.3 12 6.0 0.1 3.9 3 1 1 4 4 4 0 Sec23/Sec24 zinc finger Rubredoxin PF00301.20 KXS13527.1 - 0.98 9.5 14.5 1.6 8.8 0.6 4.1 4 0 0 4 4 4 0 Rubredoxin Vps36-NZF-N PF16988.5 KXS13527.1 - 1.2 8.6 18.5 0.81 9.1 0.6 3.8 3 1 0 3 3 3 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain PDEase_I PF00233.19 KXS13528.1 - 3.5e-74 249.5 2.5 3.8e-69 233.0 0.1 2.0 2 0 0 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase Phage_TAC_7 PF10109.9 KXS13528.1 - 0.073 13.2 0.0 0.17 12.0 0.0 1.5 1 1 0 1 1 1 0 Phage tail assembly chaperone proteins, E, or 41 or 14 F-box-like PF12937.7 KXS13530.1 - 0.0079 16.1 4.1 0.0093 15.8 0.1 2.9 2 1 1 3 3 3 1 F-box-like FAD_binding_3 PF01494.19 KXS13531.1 - 4.1e-18 65.7 0.0 5.3e-18 65.4 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KXS13531.1 - 0.029 13.6 0.3 0.27 10.4 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KXS13531.1 - 0.083 11.7 1.9 0.23 10.3 0.1 2.3 3 0 0 3 3 3 0 Tryptophan halogenase Lycopene_cycl PF05834.12 KXS13531.1 - 0.1 11.6 0.1 0.31 10.0 0.0 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein Cation_ATPase_C PF00689.21 KXS13532.1 - 2e-39 135.2 5.3 2e-39 135.2 5.3 2.0 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KXS13532.1 - 4.1e-37 127.5 0.8 4.1e-37 127.5 0.8 2.6 4 0 0 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 KXS13532.1 - 1.3e-17 64.8 0.0 4.9e-17 62.9 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KXS13532.1 - 4e-14 52.5 0.0 7.4e-14 51.6 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KXS13532.1 - 0.00021 20.9 0.0 0.00052 19.7 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KXS13532.1 - 0.00032 20.5 1.0 0.00063 19.6 0.5 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HhH-GPD PF00730.25 KXS13534.1 - 1.4e-17 64.1 0.0 7.5e-17 61.8 0.0 2.1 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein NUDIX_4 PF14815.6 KXS13534.1 - 4.3e-14 52.4 0.6 1.8e-07 31.1 0.1 2.4 2 0 0 2 2 2 2 NUDIX domain EndIII_4Fe-2S PF10576.9 KXS13534.1 - 4.9e-05 23.5 6.2 4.9e-05 23.5 6.2 1.6 2 0 0 2 2 2 1 Iron-sulfur binding domain of endonuclease III HHH PF00633.23 KXS13534.1 - 5.3e-05 22.9 0.0 0.00015 21.4 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif IQ PF00612.27 KXS13535.1 - 8.2e-19 65.6 45.4 0.00015 21.2 0.6 7.9 7 0 0 7 7 7 7 IQ calmodulin-binding motif PCMT PF01135.19 KXS13536.1 - 7.9e-79 264.3 0.0 9.5e-79 264.0 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 KXS13536.1 - 3.9e-07 30.0 0.0 5.1e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXS13536.1 - 6.2e-06 26.8 0.0 1.5e-05 25.6 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain GCD14 PF08704.10 KXS13536.1 - 7.6e-06 25.8 0.0 1e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PrmA PF06325.13 KXS13536.1 - 4e-05 23.2 0.0 5.2e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Fibrillarin PF01269.17 KXS13536.1 - 0.00019 20.6 0.0 0.0003 20.0 0.0 1.2 1 0 0 1 1 1 1 Fibrillarin MTS PF05175.14 KXS13536.1 - 0.00025 20.7 0.0 0.0004 20.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 KXS13536.1 - 0.0025 17.7 0.0 0.0042 16.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 KXS13536.1 - 0.0038 17.2 0.0 0.0058 16.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXS13536.1 - 0.0048 17.5 0.0 0.0099 16.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 KXS13536.1 - 0.0089 15.8 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase FtsJ PF01728.19 KXS13536.1 - 0.0095 16.1 0.0 0.013 15.6 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase RrnaAD PF00398.20 KXS13536.1 - 0.0099 15.0 0.0 0.015 14.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_32 PF13679.6 KXS13536.1 - 0.011 15.7 0.0 0.016 15.2 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.20 KXS13536.1 - 0.035 13.4 0.0 0.046 13.0 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_3 PF01596.17 KXS13536.1 - 0.044 13.0 0.0 0.08 12.1 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase Ubie_methyltran PF01209.18 KXS13536.1 - 0.081 12.3 0.0 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family MetW PF07021.12 KXS13536.1 - 0.18 11.3 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW DUF423 PF04241.15 KXS13537.1 - 5.6e-26 90.6 0.6 7.1e-26 90.2 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF423) GDA1_CD39 PF01150.17 KXS13539.1 - 4e-89 299.2 0.0 6.1e-89 298.6 0.0 1.2 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.16 KXS13539.1 - 0.089 12.2 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Ppx/GppA phosphatase family Peptidase_M14 PF00246.24 KXS13540.1 - 6.9e-76 255.8 0.0 1.3e-75 254.9 0.0 1.3 1 0 0 1 1 1 1 Zinc carboxypeptidase TauE PF01925.19 KXS13541.1 - 4.8e-16 59.1 33.3 4.2e-10 39.7 5.4 3.2 3 0 0 3 3 3 2 Sulfite exporter TauE/SafE MtrD PF04207.12 KXS13541.1 - 0.16 11.7 6.5 0.044 13.5 0.9 2.2 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit D LSM PF01423.22 KXS13542.1 - 8.8e-14 51.0 0.1 6.7e-11 41.7 0.1 2.3 2 0 0 2 2 2 2 LSM domain Ndc1_Nup PF09531.10 KXS13542.1 - 5.6 5.5 6.6 6.8 5.2 6.6 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF1275 PF06912.11 KXS13543.1 - 1.4e-26 93.6 15.6 1.7e-26 93.3 15.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) MRP-L27 PF09809.9 KXS13544.1 - 2.3e-17 62.8 0.1 3.3e-17 62.4 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 Mito_carr PF00153.27 KXS13545.1 - 9.9e-67 220.9 3.1 4.6e-24 84.2 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Fuseless PF15993.5 KXS13545.1 - 0.14 11.4 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 Fuseless COX14 PF14880.6 KXS13545.1 - 0.49 10.3 1.9 1.1 9.2 1.1 1.9 2 0 0 2 2 2 0 Cytochrome oxidase c assembly DSS1_SEM1 PF05160.13 KXS13546.1 - 1 9.5 16.1 4.8 7.3 12.4 2.5 1 1 1 2 2 2 0 DSS1/SEM1 family BHD_3 PF10405.9 KXS13547.1 - 5.8e-29 100.3 0.0 1.1e-28 99.5 0.0 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_2 PF10404.9 KXS13547.1 - 3.1e-18 66.5 0.4 3.1e-18 66.5 0.4 3.0 3 1 0 3 3 3 1 Rad4 beta-hairpin domain 2 BHD_1 PF10403.9 KXS13547.1 - 1.8e-17 62.9 0.0 3.7e-17 61.9 0.0 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 F-box-like PF12937.7 KXS13548.1 - 0.039 13.8 0.2 0.092 12.7 0.2 1.6 1 0 0 1 1 1 0 F-box-like CoA_transf_3 PF02515.17 KXS13549.1 - 6.1e-94 315.1 0.0 7.6e-94 314.8 0.0 1.1 1 0 0 1 1 1 1 CoA-transferase family III SAM_decarbox PF01536.16 KXS13550.1 - 5.3e-118 394.1 0.0 5.4e-116 387.5 0.0 2.0 2 0 0 2 2 2 2 Adenosylmethionine decarboxylase PH PF00169.29 KXS13551.1 - 2.3e-05 24.8 0.0 0.00011 22.7 0.0 2.1 2 0 0 2 2 2 1 PH domain RhoGEF PF00621.20 KXS13551.1 - 3.3e-05 24.2 0.1 0.016 15.4 0.0 2.4 1 1 1 2 2 2 2 RhoGEF domain Tma16 PF11176.8 KXS13552.1 - 5.1e-32 110.8 6.6 6.5e-29 100.7 6.6 2.3 1 1 0 1 1 1 1 Translation machinery-associated protein 16 TCTP PF00838.17 KXS13552.1 - 0.041 14.2 0.3 0.057 13.8 0.3 1.2 1 0 0 1 1 1 0 Translationally controlled tumour protein TMEM215 PF15746.5 KXS13552.1 - 0.19 11.2 0.8 0.3 10.5 0.8 1.3 1 0 0 1 1 1 0 TMEM215 family Hid1 PF12722.7 KXS13552.1 - 0.62 8.1 5.4 0.99 7.5 5.4 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein AAA PF00004.29 KXS13553.1 - 8.3e-17 61.8 0.0 2.3e-16 60.4 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KXS13553.1 - 5.1e-05 23.6 0.3 0.0019 18.4 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 KXS13553.1 - 0.00028 21.3 1.8 0.0019 18.6 1.8 2.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 KXS13553.1 - 0.0018 18.3 0.0 0.0035 17.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KXS13553.1 - 0.0056 16.8 0.0 0.011 15.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Vps36_ESCRT-II PF11605.8 KXS13553.1 - 0.035 14.3 0.0 0.063 13.5 0.0 1.4 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 Mg_chelatase PF01078.21 KXS13553.1 - 0.055 12.8 0.2 0.19 11.1 0.1 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Zot PF05707.12 KXS13553.1 - 0.064 12.9 0.0 6.6 6.3 0.0 2.3 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) NUDIX PF00293.28 KXS13554.1 - 4.9e-07 29.8 0.4 3.6e-05 23.8 0.4 3.1 1 1 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 KXS13554.1 - 0.0054 16.7 0.0 0.024 14.6 0.0 2.0 2 0 0 2 2 2 1 NUDIX domain Arginase PF00491.21 KXS13555.1 - 4.3e-83 279.0 0.2 6.2e-83 278.5 0.2 1.2 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 KXS13555.1 - 0.016 15.5 0.1 0.026 14.8 0.1 1.3 1 0 0 1 1 1 0 UPF0489 domain DUF3759 PF12585.8 KXS13556.1 - 7e-07 29.2 0.0 1.3e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) S1 PF00575.23 KXS13557.1 - 3.3e-13 49.8 0.0 8.6e-13 48.4 0.0 1.7 1 0 0 1 1 1 1 S1 RNA binding domain zf-CCHC_3 PF13917.6 KXS13557.1 - 0.0015 18.4 0.3 0.0046 16.9 0.3 1.8 1 0 0 1 1 1 1 Zinc knuckle DUF1682 PF07946.14 KXS13557.1 - 0.011 15.0 13.5 0.011 15.0 13.5 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1682) zf-CCHC PF00098.23 KXS13557.1 - 0.17 12.0 1.8 0.35 11.0 1.8 1.4 1 0 0 1 1 1 0 Zinc knuckle Glyco_hydro_26 PF02156.15 KXS13558.1 - 2.6e-10 40.2 0.6 4.2e-07 29.7 0.0 2.3 2 0 0 2 2 2 2 Glycosyl hydrolase family 26 EF-hand_5 PF13202.6 KXS13558.1 - 0.22 11.1 0.7 0.43 10.2 0.7 1.5 1 0 0 1 1 1 0 EF hand zf-AN1 PF01428.16 KXS13559.1 - 6.9e-12 45.3 2.7 1e-11 44.8 2.7 1.3 1 0 0 1 1 1 1 AN1-like Zinc finger CCDC53 PF10152.9 KXS13559.1 - 1.5 9.2 5.5 1.8 9.0 5.5 1.1 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex SUIM_assoc PF16619.5 KXS13559.1 - 1.7 8.8 13.8 2.5 8.2 13.8 1.3 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 F-box-like PF12937.7 KXS13560.1 - 0.00027 20.7 0.1 0.00086 19.2 0.1 1.9 1 0 0 1 1 1 1 F-box-like TMEM213 PF15192.6 KXS13560.1 - 0.063 13.3 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 TMEM213 family F-box PF00646.33 KXS13560.1 - 0.066 13.1 0.0 0.23 11.4 0.0 2.0 1 0 0 1 1 1 0 F-box domain LRR_4 PF12799.7 KXS13560.1 - 4.1 8.0 7.3 4.5 7.8 0.3 3.5 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) FAD-oxidase_C PF02913.19 KXS13561.1 - 9.3e-53 179.4 0.2 1.3e-52 178.9 0.2 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KXS13561.1 - 7.6e-34 116.4 0.1 1.4e-33 115.5 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain PDZ_3 PF17815.1 KXS13562.1 - 2.3e-34 118.3 0.0 3.7e-34 117.7 0.0 1.3 1 0 0 1 1 1 1 PDZ domain Trypsin_2 PF13365.6 KXS13562.1 - 3.2e-21 76.8 0.0 6.8e-21 75.7 0.0 1.6 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 KXS13562.1 - 1.9e-16 60.5 0.0 3e-16 59.9 0.0 1.3 1 0 0 1 1 1 1 Trypsin PDZ_2 PF13180.6 KXS13562.1 - 1e-07 32.1 2.6 7.2e-05 23.0 0.0 4.0 2 1 1 3 3 3 1 PDZ domain PDZ_6 PF17820.1 KXS13562.1 - 0.00077 19.3 0.7 0.51 10.2 0.0 3.0 3 0 0 3 3 3 2 PDZ domain PDZ PF00595.24 KXS13562.1 - 0.00079 19.7 0.1 0.06 13.7 0.0 2.8 2 1 0 2 2 2 1 PDZ domain Peptidase_S46 PF10459.9 KXS13562.1 - 0.011 14.5 0.0 0.016 13.9 0.0 1.2 1 0 0 1 1 1 0 Peptidase S46 Peptidase_S7 PF00949.21 KXS13562.1 - 0.083 12.7 0.1 0.17 11.7 0.1 1.5 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease Aldo_ket_red PF00248.21 KXS13563.1 - 8e-47 159.8 0.0 9.3e-47 159.6 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Filo_VP35 PF02097.15 KXS13563.1 - 0.13 11.3 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 Filoviridae VP35 Uds1 PF15456.6 KXS13564.1 - 1.5e-11 44.6 6.1 1.5e-11 44.6 6.1 12.6 3 2 7 10 10 10 1 Up-regulated During Septation AAA_13 PF13166.6 KXS13564.1 - 0.00025 19.8 20.9 0.00025 19.8 20.9 6.3 2 1 4 6 6 6 1 AAA domain TPR_MLP1_2 PF07926.12 KXS13564.1 - 0.0011 19.0 27.4 0.0011 19.0 27.4 11.1 4 2 5 11 11 11 1 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.9 KXS13564.1 - 0.0028 17.7 22.1 0.0028 17.7 22.1 9.6 3 2 7 10 10 10 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATG16 PF08614.11 KXS13564.1 - 0.005 17.1 18.1 0.005 17.1 18.1 9.8 3 1 6 9 9 9 1 Autophagy protein 16 (ATG16) Alanine_zipper PF11839.8 KXS13564.1 - 0.0058 17.0 10.3 0.0058 17.0 10.3 14.5 6 2 6 12 12 12 5 Alanine-zipper, major outer membrane lipoprotein RTBV_P46 PF06216.11 KXS13564.1 - 0.055 12.3 0.3 0.13 11.1 0.1 1.5 1 1 0 1 1 1 0 Rice tungro bacilliform virus P46 protein Fusion_gly PF00523.18 KXS13564.1 - 0.19 10.0 0.5 0.56 8.4 0.5 1.8 1 0 0 1 1 1 0 Fusion glycoprotein F0 Laminin_II PF06009.12 KXS13564.1 - 8.9 6.3 107.0 0.028 14.5 4.3 10.9 3 2 6 11 11 11 0 Laminin Domain II WD40 PF00400.32 KXS13565.1 - 2.9e-17 62.7 2.1 3.8e-05 24.4 0.1 6.7 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXS13565.1 - 0.0034 17.6 0.0 8.8 6.7 0.0 4.0 3 2 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 KXS13565.1 - 0.036 14.6 7.2 37 5.0 0.0 5.6 6 1 0 6 6 6 0 PQQ-like domain p450 PF00067.22 KXS13566.1 - 8.8e-67 225.8 0.0 1.1e-66 225.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Potass_KdpF PF09604.10 KXS13566.1 - 3.6 7.7 6.3 6.4 6.9 6.3 1.4 1 0 0 1 1 1 0 F subunit of K+-transporting ATPase (Potass_KdpF) HSP90 PF00183.18 KXS13569.1 - 0.21 10.4 5.6 0.39 9.6 0.0 2.0 2 0 0 2 2 2 0 Hsp90 protein PGF-CTERM PF18204.1 KXS13569.1 - 0.22 11.6 4.2 0.43 10.6 4.2 1.5 1 0 0 1 1 1 0 PGF-CTERM motif Presenilin PF01080.17 KXS13569.1 - 0.44 9.3 7.1 0.6 8.8 7.1 1.1 1 0 0 1 1 1 0 Presenilin Zip PF02535.22 KXS13569.1 - 0.85 8.8 11.6 1.1 8.4 11.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter CKAP2_C PF15297.6 KXS13569.1 - 1.1 8.3 5.4 1.6 7.8 5.4 1.1 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus RP-C_C PF11800.8 KXS13569.1 - 6.6 6.8 6.7 12 5.9 6.7 1.4 1 0 0 1 1 1 0 Replication protein C C-terminal region CCDC106 PF15794.5 KXS13569.1 - 7.5 6.2 9.6 12 5.6 9.6 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 WW_1 PF18507.1 KXS13570.1 - 0.036 13.8 0.1 7.2 6.4 0.0 2.5 2 0 0 2 2 2 0 WW domain RNA_pol_3_Rpc31 PF11705.8 KXS13571.1 - 0.0061 16.8 27.8 0.032 14.5 5.4 3.5 3 1 0 3 3 3 3 DNA-directed RNA polymerase III subunit Rpc31 Dicty_REP PF05086.12 KXS13571.1 - 7.2 4.4 7.1 12 3.7 7.1 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein La PF05383.17 KXS13572.1 - 2.4e-06 27.5 0.0 3.4e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 La domain Vault PF01505.18 KXS13572.1 - 0.11 12.7 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 Major Vault Protein repeat domain HEAT PF02985.22 KXS13573.1 - 7.1e-09 35.2 14.7 0.9 10.0 0.1 9.8 10 0 0 10 10 10 4 HEAT repeat HEAT_EZ PF13513.6 KXS13573.1 - 1.3e-08 35.1 16.5 0.093 13.3 0.1 8.8 9 2 2 11 11 11 4 HEAT-like repeat HEAT_2 PF13646.6 KXS13573.1 - 5.3e-05 23.5 10.3 4.8 7.6 0.1 7.1 6 1 0 6 6 6 2 HEAT repeats Arm PF00514.23 KXS13573.1 - 0.0047 16.9 0.2 5.2 7.3 0.1 4.6 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 KXS13573.1 - 0.026 14.6 0.2 13 5.8 0.0 3.3 2 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 DUF3149 PF11346.8 KXS13574.1 - 0.041 13.5 5.8 0.082 12.5 5.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) DUF4389 PF14333.6 KXS13574.1 - 7.1 6.6 10.1 0.63 10.0 1.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4389) MMR_HSR1 PF01926.23 KXS13575.1 - 2.1e-05 24.5 0.0 0.0013 18.8 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KXS13575.1 - 0.00087 18.9 0.0 0.46 10.0 0.0 2.5 3 0 0 3 3 3 2 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 KXS13575.1 - 0.068 13.5 0.0 0.56 10.6 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain RsgA_GTPase PF03193.16 KXS13575.1 - 0.33 10.8 1.7 0.59 10.0 0.0 2.2 3 0 0 3 3 3 0 RsgA GTPase Arm PF00514.23 KXS13577.1 - 7.6e-09 35.3 2.0 0.00024 21.0 0.1 4.6 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KXS13577.1 - 0.00014 22.2 0.8 0.046 14.3 0.0 3.9 3 0 0 3 3 3 1 HEAT-like repeat HEAT PF02985.22 KXS13577.1 - 0.019 15.2 0.1 0.34 11.3 0.0 3.1 3 0 0 3 3 3 0 HEAT repeat HEAT_2 PF13646.6 KXS13577.1 - 0.021 15.2 0.0 0.16 12.4 0.0 2.6 2 0 0 2 2 2 0 HEAT repeats RINGv PF12906.7 KXS13578.1 - 0.6 10.3 6.9 1 9.5 6.9 1.4 1 0 0 1 1 1 0 RING-variant domain Asn_synthase PF00733.21 KXS13579.1 - 5.2e-91 305.9 0.0 7.5e-56 190.3 0.0 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 KXS13579.1 - 2.2e-37 127.7 0.0 3.5e-37 127.1 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 KXS13579.1 - 3.5e-29 101.7 0.0 5.7e-29 101.0 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 KXS13579.1 - 3.2e-10 39.8 0.0 5.6e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 KXS13579.1 - 0.0049 16.0 0.0 0.0078 15.4 0.0 1.3 1 0 0 1 1 1 1 NAD synthase PhyH PF05721.13 KXS13580.1 - 7e-18 65.7 0.0 9.2e-18 65.3 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) SIT PF15330.6 KXS13580.1 - 0.19 12.2 0.0 0.29 11.6 0.0 1.3 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT RWD PF05773.22 KXS13581.1 - 1.1e-20 74.0 0.0 2e-20 73.2 0.0 1.4 1 0 0 1 1 1 1 RWD domain DFRP_C PF16543.5 KXS13581.1 - 5.1e-08 33.3 2.8 5.1e-08 33.3 2.8 2.9 1 1 2 3 3 3 1 DRG Family Regulatory Proteins, Tma46 RRM_1 PF00076.22 KXS13582.1 - 1.9e-16 59.7 0.0 3.2e-16 58.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CAF1C_H4-bd PF12265.8 KXS13583.1 - 1.5e-16 60.4 0.0 2e-15 56.8 0.0 2.4 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 KXS13583.1 - 1.2e-14 54.5 15.6 7.4e-07 29.8 0.8 5.8 7 0 0 7 7 7 3 WD domain, G-beta repeat Lactonase PF10282.9 KXS13583.1 - 0.043 13.1 0.0 0.18 11.0 0.0 2.0 2 1 0 2 2 2 0 Lactonase, 7-bladed beta-propeller F-box-like PF12937.7 KXS13584.1 - 0.0028 17.5 0.2 0.0067 16.3 0.2 1.7 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.6 KXS13584.1 - 0.056 13.5 0.7 2.8 8.2 0.0 3.2 3 0 0 3 3 3 0 Leucine Rich repeat Abhydrolase_1 PF00561.20 KXS13585.1 - 1.7e-29 103.3 0.0 2.6e-29 102.6 0.0 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXS13585.1 - 1.8e-14 54.9 0.0 2.5e-14 54.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXS13585.1 - 2.8e-07 30.0 0.0 1.9e-06 27.3 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 KXS13585.1 - 0.00011 21.0 0.0 0.00017 20.4 0.0 1.3 1 0 0 1 1 1 1 Ndr family DLH PF01738.18 KXS13585.1 - 0.0017 17.9 0.0 0.064 12.8 0.0 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family EHN PF06441.12 KXS13585.1 - 0.0095 16.3 0.0 0.023 15.0 0.0 1.7 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Sec34 PF04136.15 KXS13586.1 - 5.5e-40 136.7 8.4 1.3e-39 135.4 8.4 1.7 1 0 0 1 1 1 1 Sec34-like family SKA2 PF16740.5 KXS13586.1 - 0.021 14.6 0.7 0.11 12.3 0.4 2.5 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 GyrB_insert PF18053.1 KXS13586.1 - 0.024 14.5 1.4 0.072 13.0 0.0 2.6 3 0 0 3 3 3 0 DNA gyrase B subunit insert domain Helitron_like_N PF14214.6 KXS13586.1 - 0.18 12.0 0.1 1.2 9.3 0.0 2.4 2 0 0 2 2 2 0 Helitron helicase-like domain at N-terminus CENP-H PF05837.12 KXS13586.1 - 0.24 11.8 3.4 1.1 9.7 1.0 2.8 2 0 0 2 2 2 0 Centromere protein H (CENP-H) SIR2 PF02146.17 KXS13587.1 - 1.7e-47 161.6 0.0 2.9e-47 160.9 0.0 1.4 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 KXS13587.1 - 0.006 16.3 0.0 3.5 7.4 0.0 2.5 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain DUF592 PF04574.13 KXS13587.1 - 0.02 14.7 0.0 0.057 13.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF592) NOA36 PF06524.12 KXS13587.1 - 2.2 7.5 7.4 4.6 6.5 6.1 1.8 1 1 1 2 2 2 0 NOA36 protein DSPc PF00782.20 KXS13588.1 - 7.1e-05 22.6 0.0 0.00015 21.6 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KXS13588.1 - 0.0022 17.6 0.0 0.0031 17.1 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase polyprenyl_synt PF00348.17 KXS13589.1 - 8.7e-67 224.9 0.0 1e-66 224.6 0.0 1.0 1 0 0 1 1 1 1 Polyprenyl synthetase Terpene_synth_C PF03936.16 KXS13589.1 - 0.089 12.1 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Terpene synthase family, metal binding domain Tropomyosin_1 PF12718.7 KXS13590.1 - 3.4e-26 92.1 28.5 4.6e-26 91.7 28.5 1.2 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.20 KXS13590.1 - 8.3e-13 48.3 31.4 1.6e-06 27.7 11.4 3.0 1 1 2 3 3 3 3 Tropomyosin TPR_MLP1_2 PF07926.12 KXS13590.1 - 3.9e-05 23.7 29.9 0.017 15.2 5.5 2.1 1 1 1 2 2 2 2 TPR/MLP1/MLP2-like protein PspA_IM30 PF04012.12 KXS13590.1 - 0.00016 21.3 25.0 0.0033 17.0 6.4 2.2 1 1 1 2 2 2 2 PspA/IM30 family TMF_DNA_bd PF12329.8 KXS13590.1 - 0.00068 19.6 7.2 0.00068 19.6 7.2 3.4 1 1 1 3 3 3 1 TATA element modulatory factor 1 DNA binding DHR10 PF18595.1 KXS13590.1 - 0.0043 17.1 8.0 0.0043 17.1 8.0 2.5 1 1 1 2 2 2 1 Designed helical repeat protein 10 domain ATG16 PF08614.11 KXS13590.1 - 0.0065 16.7 31.1 0.81 9.9 14.5 2.2 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) DUF812 PF05667.11 KXS13590.1 - 0.014 14.3 27.1 0.017 14.0 27.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) HrpB7 PF09486.10 KXS13590.1 - 0.019 15.4 4.8 0.019 15.4 4.8 3.0 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) DUF1598 PF07643.11 KXS13590.1 - 0.027 14.7 1.0 0.085 13.1 0.1 2.2 1 1 2 3 3 3 0 Protein of unknown function (DUF1598) DUF3584 PF12128.8 KXS13590.1 - 0.031 11.8 26.4 0.038 11.5 26.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Laminin_II PF06009.12 KXS13590.1 - 0.032 14.2 16.7 0.17 11.9 8.6 2.6 1 1 1 2 2 2 0 Laminin Domain II DUF1192 PF06698.11 KXS13590.1 - 0.064 13.3 2.3 0.064 13.3 2.3 3.7 2 2 1 5 5 2 0 Protein of unknown function (DUF1192) Fez1 PF06818.15 KXS13590.1 - 0.09 13.2 25.7 2.6 8.5 25.6 2.0 1 1 0 1 1 1 0 Fez1 CENP-F_leu_zip PF10473.9 KXS13590.1 - 0.12 12.4 30.6 0.19 11.7 14.1 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ADIP PF11559.8 KXS13590.1 - 0.13 12.3 29.3 0.44 10.6 1.4 3.1 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Tup_N PF08581.10 KXS13590.1 - 0.14 12.5 17.1 0.054 13.8 2.2 2.6 1 1 0 2 2 2 0 Tup N-terminal Spc7 PF08317.11 KXS13590.1 - 0.18 10.6 30.2 0.019 13.9 9.3 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein EzrA PF06160.12 KXS13590.1 - 0.21 9.7 22.7 0.52 8.4 22.7 1.6 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA GAS PF13851.6 KXS13590.1 - 0.22 10.9 26.6 13 5.1 20.9 2.2 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Alanine_zipper PF11839.8 KXS13590.1 - 0.24 11.8 12.9 7.5 7.0 0.3 3.6 2 1 2 4 4 4 0 Alanine-zipper, major outer membrane lipoprotein DUF2461 PF09365.10 KXS13590.1 - 0.25 11.3 4.1 0.13 12.3 1.6 1.8 1 1 1 2 2 2 0 Conserved hypothetical protein (DUF2461) TMF_TATA_bd PF12325.8 KXS13590.1 - 0.32 11.2 25.5 1.7 8.9 13.5 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding ABC_tran_CTD PF16326.5 KXS13590.1 - 0.33 11.2 29.9 0.53 10.6 8.5 3.3 2 1 1 3 3 3 0 ABC transporter C-terminal domain Fmp27_WPPW PF10359.9 KXS13590.1 - 0.33 9.7 20.8 0.45 9.3 11.0 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain FlaC_arch PF05377.11 KXS13590.1 - 0.34 11.3 18.7 1.3 9.5 2.1 4.4 1 1 4 5 5 5 0 Flagella accessory protein C (FlaC) DUF4200 PF13863.6 KXS13590.1 - 0.35 11.3 32.4 0.15 12.5 6.5 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) APG17 PF04108.12 KXS13590.1 - 0.43 9.6 17.1 2.7 7.0 4.6 2.1 1 1 1 2 2 2 0 Autophagy protein Apg17 PKcGMP_CC PF16808.5 KXS13590.1 - 0.46 10.4 0.0 0.46 10.4 0.0 4.1 4 1 1 5 5 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Lectin_N PF03954.14 KXS13590.1 - 0.47 10.2 13.6 2.7 7.7 2.4 3.3 1 1 3 4 4 4 0 Hepatic lectin, N-terminal domain Seryl_tRNA_N PF02403.22 KXS13590.1 - 0.51 10.6 25.7 0.24 11.7 12.6 2.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF3450 PF11932.8 KXS13590.1 - 0.52 9.6 23.7 0.12 11.7 3.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF1664 PF07889.12 KXS13590.1 - 0.61 10.1 15.5 0.19 11.8 1.7 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DASH_Spc19 PF08287.11 KXS13590.1 - 0.66 9.9 26.1 0.78 9.6 19.8 2.8 1 1 2 3 3 3 0 Spc19 DUF745 PF05335.13 KXS13590.1 - 0.72 9.5 19.1 3.2 7.5 19.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF745) DUF724 PF05266.14 KXS13590.1 - 0.8 9.5 25.2 0.2 11.5 6.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF724) FAM76 PF16046.5 KXS13590.1 - 0.93 8.8 20.2 0.51 9.7 2.0 2.1 1 1 1 2 2 2 0 FAM76 protein DUF948 PF06103.11 KXS13590.1 - 1.1 9.6 11.8 0.98 9.7 0.7 2.9 1 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Prefoldin_2 PF01920.20 KXS13590.1 - 1.1 9.2 32.0 0.42 10.6 1.8 4.1 1 1 3 4 4 4 0 Prefoldin subunit ERM PF00769.19 KXS13590.1 - 1.2 9.0 32.4 1.4 8.6 6.6 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family DUF4795 PF16043.5 KXS13590.1 - 1.2 8.7 23.4 1.2e+02 2.1 23.4 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) DUF1818 PF08848.11 KXS13590.1 - 1.2 9.2 8.4 0.78 9.9 1.4 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF1818) Atg14 PF10186.9 KXS13590.1 - 1.2 8.1 26.4 71 2.3 26.3 2.0 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 KASH_CCD PF14662.6 KXS13590.1 - 1.3 8.8 27.2 0.88 9.4 22.8 2.0 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH AAA_13 PF13166.6 KXS13590.1 - 1.6 7.3 22.4 0.13 10.9 4.8 2.0 1 1 1 2 2 2 0 AAA domain FAP206 PF12018.8 KXS13590.1 - 1.6 8.2 13.9 0.36 10.3 9.0 1.9 1 1 1 2 2 2 0 Domain of unknown function CLZ PF16526.5 KXS13590.1 - 1.7 9.1 26.4 47 4.5 15.6 3.5 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels SlyX PF04102.12 KXS13590.1 - 1.7 9.3 22.6 1.5 9.5 8.0 3.3 2 1 1 3 3 3 0 SlyX Ku_N PF03731.15 KXS13590.1 - 1.8 8.3 11.1 4 7.1 3.4 2.0 1 1 1 2 2 2 0 Ku70/Ku80 N-terminal alpha/beta domain Fib_alpha PF08702.10 KXS13590.1 - 1.9 8.7 16.8 3 8.0 6.6 2.5 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family BLOC1_2 PF10046.9 KXS13590.1 - 2.3 8.6 19.3 1.7 9.0 2.9 2.8 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 T2SSF PF00482.23 KXS13590.1 - 2.4 8.2 4.4 0.69 9.9 0.5 2.1 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F COG2 PF06148.11 KXS13590.1 - 2.5 8.2 15.5 2.9 8.0 4.9 3.0 1 1 3 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 LPP PF04728.13 KXS13590.1 - 2.7 8.4 10.2 18 5.8 0.0 3.9 2 2 2 4 4 4 0 Lipoprotein leucine-zipper FUSC PF04632.12 KXS13590.1 - 2.7 6.4 5.9 3.2 6.2 5.9 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF4407 PF14362.6 KXS13590.1 - 2.8 7.2 21.9 9.4 5.5 21.9 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) CHDCT2 PF08074.11 KXS13590.1 - 3.2 7.9 8.6 1.4 9.1 5.4 1.8 1 1 1 2 2 2 0 CHDCT2 (NUC038) domain DUF4337 PF14235.6 KXS13590.1 - 3.3 7.8 23.0 5.5 7.1 5.3 3.2 1 1 1 3 3 3 0 Domain of unknown function (DUF4337) PA26 PF04636.13 KXS13590.1 - 3.8 6.3 8.6 4.8 6.0 8.6 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Cep57_CLD_2 PF14197.6 KXS13590.1 - 4.1 7.6 27.4 1.2 9.2 6.1 4.0 1 1 2 4 4 4 0 Centrosome localisation domain of PPC89 XhlA PF10779.9 KXS13590.1 - 4.2 7.6 25.5 0.95 9.7 1.1 4.0 2 1 2 4 4 4 0 Haemolysin XhlA Ax_dynein_light PF10211.9 KXS13590.1 - 4.5 7.2 26.8 3.5 7.5 9.2 3.1 1 1 2 3 3 3 0 Axonemal dynein light chain Troponin PF00992.20 KXS13590.1 - 5.3 7.4 25.4 0.4 11.0 3.4 2.8 1 1 1 2 2 2 0 Troponin DUF16 PF01519.16 KXS13590.1 - 5.4 7.5 20.4 0.067 13.7 3.7 2.8 1 1 2 3 3 3 0 Protein of unknown function DUF16 CSN5_C PF18323.1 KXS13590.1 - 5.7 7.9 14.7 2.1 9.3 5.6 2.6 1 1 2 3 3 2 0 Cop9 signalosome subunit 5 C-terminal domain UPF0242 PF06785.11 KXS13590.1 - 5.8 7.0 27.5 18 5.4 16.2 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Bacillus_HBL PF05791.11 KXS13590.1 - 6.3 6.6 13.6 0.69 9.7 1.7 2.1 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DUF641 PF04859.12 KXS13590.1 - 7.2 7.0 20.8 0.06 13.7 1.9 2.9 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) APG6_N PF17675.1 KXS13590.1 - 8.6 6.9 34.8 74 3.9 15.4 2.5 1 1 1 2 2 2 0 Apg6 coiled-coil region Casc1_N PF15927.5 KXS13590.1 - 9.8 5.8 28.2 6.2 6.5 14.8 2.2 1 1 0 2 2 2 0 Cancer susceptibility candidate 1 N-terminus Dus PF01207.17 KXS13591.1 - 3.9e-39 134.6 0.0 5e-37 127.6 0.0 2.1 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) peroxidase PF00141.23 KXS13592.1 - 5.2e-54 183.4 0.0 7.6e-54 182.8 0.0 1.2 1 0 0 1 1 1 1 Peroxidase Ntox4 PF15541.6 KXS13592.1 - 0.19 12.1 0.0 0.48 10.8 0.0 1.6 2 0 0 2 2 2 0 Bacterial toxin 4 ArAE_2_N PF10337.9 KXS13593.1 - 7.3e-16 58.3 10.7 5.4e-11 42.2 0.1 3.2 2 1 1 3 3 3 2 Putative ER transporter, 6TM, N-terminal FUSC_2 PF13515.6 KXS13593.1 - 6.2e-15 55.4 22.5 6.2e-15 55.4 22.5 3.2 2 2 1 3 3 3 1 Fusaric acid resistance protein-like ALMT PF11744.8 KXS13593.1 - 2.2e-11 43.3 15.9 4.8e-10 38.9 15.9 2.2 2 0 0 2 2 2 1 Aluminium activated malate transporter FUSC PF04632.12 KXS13593.1 - 3.5e-06 25.9 27.2 2.3e-05 23.2 15.2 2.5 2 0 0 2 2 2 2 Fusaric acid resistance protein family ArAE_1 PF06081.11 KXS13593.1 - 4.6 7.4 17.9 0.14 12.3 10.3 2.4 2 0 0 2 2 2 0 Aromatic acid exporter family member 1 RNA_pol_Rpb4 PF03874.16 KXS13595.1 - 5e-13 49.5 0.0 5.9e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb4 GDP_Man_Dehyd PF16363.5 KXS13596.1 - 2.5e-58 198.0 0.0 5.5e-58 196.9 0.0 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KXS13596.1 - 1.3e-48 165.6 0.0 1.5e-48 165.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXS13596.1 - 1.4e-10 40.7 0.0 2.1e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KXS13596.1 - 5.4e-10 38.9 0.1 5.2e-07 29.1 0.0 2.5 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 KXS13596.1 - 1.5e-09 37.4 0.1 1.6e-05 24.2 0.0 2.3 1 1 1 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 KXS13596.1 - 5.1e-09 35.6 0.0 6.5e-09 35.3 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 KXS13596.1 - 0.024 14.1 0.0 0.039 13.4 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase ANAPC_CDC26 PF10471.9 KXS13598.1 - 0.16 12.8 3.2 0.21 12.5 3.2 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit CDC26 Pkinase_Tyr PF07714.17 KXS13601.1 - 3.6e-09 36.3 0.0 4.7e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXS13601.1 - 6.2e-09 35.6 0.0 1e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Sel1 PF08238.12 KXS13601.1 - 0.00018 22.1 0.5 0.003 18.2 0.3 2.2 2 0 0 2 2 2 1 Sel1 repeat Amidohydro_1 PF01979.20 KXS13602.1 - 6.8e-57 193.3 0.0 8.3e-57 193.0 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KXS13602.1 - 6.2e-19 68.8 0.5 1.4e-11 44.5 0.1 2.3 2 0 0 2 2 2 2 Amidohydrolase family TPT PF03151.16 KXS13603.1 - 9.3e-27 94.1 16.9 1.1e-26 93.9 16.9 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 KXS13603.1 - 1.7e-09 37.3 13.5 2.6e-09 36.7 13.5 1.3 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 KXS13603.1 - 1.4e-06 28.5 29.5 0.00077 19.7 10.1 2.3 2 0 0 2 2 2 2 EamA-like transporter family Dynactin_p22 PF07426.11 KXS13604.1 - 9.8e-12 45.0 0.0 2.2e-11 43.9 0.0 1.5 2 0 0 2 2 2 1 Dynactin subunit p22 zf-C3HC4_3 PF13920.6 KXS13605.1 - 4.2e-07 29.7 7.5 4.2e-07 29.7 7.5 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KXS13605.1 - 0.0028 17.5 6.3 0.0028 17.5 6.3 2.9 4 0 0 4 4 4 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 KXS13605.1 - 0.0094 15.8 7.4 0.0094 15.8 7.4 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Adaptin_binding PF10199.9 KXS13606.1 - 3.5e-11 43.8 0.1 1.6e-10 41.6 0.0 2.4 2 2 0 2 2 2 1 Alpha and gamma adaptin binding protein p34 Ribosom_S12_S23 PF00164.25 KXS13607.1 - 1.7e-37 127.5 2.6 3.1e-37 126.7 2.6 1.4 1 0 0 1 1 1 1 Ribosomal protein S12/S23 DUF2574 PF10836.8 KXS13607.1 - 0.088 12.7 0.4 0.2 11.6 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2574) Aminotran_5 PF00266.19 KXS13608.1 - 1.2e-32 113.4 0.0 1.8e-32 112.8 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KXS13608.1 - 0.00011 21.6 0.0 0.00028 20.3 0.0 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 KXS13608.1 - 0.016 13.8 0.0 0.021 13.4 0.0 1.1 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 KXS13609.1 - 3.3e-30 105.3 0.0 4.7e-30 104.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KXS13609.1 - 9.6e-06 25.1 0.0 2.5e-05 23.7 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase TAF8_C PF10406.9 KXS13610.1 - 1.9e-07 31.5 0.5 1.9e-07 31.5 0.5 2.7 3 0 0 3 3 3 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.13 KXS13610.1 - 3.3e-05 23.8 0.0 6.3e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated NPR3 PF03666.13 KXS13610.1 - 4.4 6.0 10.1 6.3 5.5 10.1 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Paf1 PF03985.13 KXS13610.1 - 4.6 6.1 17.2 7 5.5 17.2 1.2 1 0 0 1 1 1 0 Paf1 Glyco_transf_90 PF05686.12 KXS13611.1 - 1.9e-18 66.6 0.0 4.6e-18 65.3 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 90 DNA_RNApol_7kD PF03604.13 KXS13612.1 - 3.5e-18 65.0 5.4 5.6e-18 64.3 5.4 1.3 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit DZR PF12773.7 KXS13612.1 - 0.00022 21.2 0.6 0.00028 20.8 0.6 1.1 1 0 0 1 1 1 1 Double zinc ribbon Zn_ribbon_SprT PF17283.2 KXS13612.1 - 0.0026 17.6 1.5 1 9.3 0.4 2.2 2 0 0 2 2 2 2 SprT-like zinc ribbon domain zinc_ribbon_13 PF09855.9 KXS13612.1 - 0.0092 16.1 0.3 0.0092 16.1 0.3 1.7 1 1 1 2 2 2 1 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) OrfB_Zn_ribbon PF07282.11 KXS13612.1 - 0.017 15.0 0.7 0.022 14.7 0.7 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-NADH-PPase PF09297.11 KXS13612.1 - 0.019 14.6 1.9 0.057 13.1 1.9 1.8 1 1 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain MCM_OB PF17207.3 KXS13612.1 - 0.022 14.6 0.4 0.023 14.6 0.4 1.1 1 0 0 1 1 1 0 MCM OB domain HypA PF01155.19 KXS13612.1 - 0.024 14.7 0.3 0.028 14.5 0.3 1.1 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-ISL3 PF14690.6 KXS13612.1 - 0.039 14.6 3.7 0.11 13.2 0.1 2.4 2 1 1 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zinc-ribbon_6 PF10005.9 KXS13612.1 - 0.039 14.6 0.2 0.049 14.3 0.2 1.2 1 0 0 1 1 1 0 zinc-ribbon domain Rubredoxin_2 PF18073.1 KXS13612.1 - 0.051 13.3 5.4 1.8 8.4 0.6 2.2 2 0 0 2 2 2 0 Rubredoxin metal binding domain TFIIS_C PF01096.18 KXS13612.1 - 0.051 13.4 0.7 6.2 6.8 0.1 2.3 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) zinc_ribbon_10 PF10058.9 KXS13612.1 - 0.069 12.9 2.4 0.5 10.1 0.1 2.2 1 1 1 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein Zn_ribbon_recom PF13408.6 KXS13612.1 - 0.07 13.6 5.0 1.1 9.9 0.4 2.1 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain zinc_ribbon_2 PF13240.6 KXS13612.1 - 0.11 12.2 6.5 2 8.2 6.5 2.2 1 1 0 1 1 1 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 KXS13612.1 - 0.13 11.7 4.3 0.63 9.5 4.3 1.9 1 1 0 1 1 1 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 KXS13612.1 - 0.2 11.8 3.6 0.57 10.3 3.5 1.8 1 1 1 2 2 2 0 Zinc ribbon domain A2L_zn_ribbon PF08792.10 KXS13612.1 - 0.22 11.3 3.3 0.57 10.0 3.2 1.7 1 1 1 2 2 2 0 A2L zinc ribbon domain zf-HYPF PF07503.12 KXS13612.1 - 0.36 10.6 4.6 0.55 10.1 0.1 2.3 2 1 0 2 2 2 0 HypF finger TF_Zn_Ribbon PF08271.12 KXS13612.1 - 1.4 8.5 6.7 19 4.8 6.7 2.1 1 1 0 1 1 1 0 TFIIB zinc-binding Ferrochelatase PF00762.19 KXS13613.1 - 4.2e-107 357.9 0.0 4.8e-107 357.7 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase CbiX PF01903.17 KXS13613.1 - 0.067 13.5 0.0 27 5.1 0.0 3.2 3 1 0 3 3 3 0 CbiX WD40 PF00400.32 KXS13615.1 - 3.9e-09 37.0 15.0 0.059 14.3 0.0 6.4 6 1 0 6 6 6 4 WD domain, G-beta repeat Dynein_IC2 PF11540.8 KXS13615.1 - 4.3e-06 26.6 0.1 8.9e-06 25.6 0.1 1.6 1 0 0 1 1 1 1 Cytoplasmic dynein 1 intermediate chain 2 ANAPC4_WD40 PF12894.7 KXS13615.1 - 0.11 12.9 0.0 0.92 9.8 0.0 2.5 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain SNF2_N PF00176.23 KXS13616.1 - 4.6e-70 236.1 0.0 9.5e-70 235.0 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KXS13616.1 - 6e-19 68.4 0.1 4.6e-18 65.6 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain HSA PF07529.13 KXS13616.1 - 1.3e-13 51.1 15.6 1.3e-13 51.1 15.6 2.5 3 0 0 3 3 3 1 HSA ResIII PF04851.15 KXS13616.1 - 2.6e-12 47.1 0.0 7.4e-12 45.6 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 KXS13616.1 - 2.7e-05 23.9 0.0 6.7e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 SWI2/SNF2 ATPase DEAD PF00270.29 KXS13616.1 - 0.0001 22.2 0.0 0.00027 20.7 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase QLQ PF08880.11 KXS13616.1 - 0.00036 20.2 0.0 0.00076 19.2 0.0 1.6 1 0 0 1 1 1 1 QLQ AT_hook PF02178.19 KXS13616.1 - 0.39 10.7 4.5 1.5 8.9 4.5 2.1 1 0 0 1 1 1 0 AT hook motif Amidase PF01425.21 KXS13617.1 - 5.5e-97 325.5 0.0 6.5e-97 325.3 0.0 1.0 1 0 0 1 1 1 1 Amidase RRM_1 PF00076.22 KXS13618.1 - 1.3e-23 82.6 0.0 2.1e-23 81.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF2_hinge PF14327.6 KXS13618.1 - 8.4e-17 61.4 1.4 2.8e-16 59.7 1.4 1.9 1 0 0 1 1 1 1 Hinge domain of cleavage stimulation factor subunit 2 CSTF_C PF14304.6 KXS13618.1 - 5.6e-09 35.4 4.6 2.6e-08 33.3 4.6 2.1 1 0 0 1 1 1 1 Transcription termination and cleavage factor C-terminal RRM_7 PF16367.5 KXS13618.1 - 0.014 15.5 0.0 0.036 14.2 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif CDC45 PF02724.14 KXS13618.1 - 5.7 5.1 19.5 7.7 4.7 19.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Transglut_core PF01841.19 KXS13619.1 - 1.1e-05 25.9 0.0 6.2e-05 23.4 0.0 2.4 2 0 0 2 2 2 1 Transglutaminase-like superfamily DUF5622 PF18533.1 KXS13619.1 - 0.021 15.0 0.0 0.06 13.5 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5622) HGD-D PF06050.13 KXS13619.1 - 0.059 13.1 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 2-hydroxyglutaryl-CoA dehydratase, D-component Transglut_core3 PF13471.6 KXS13619.1 - 0.15 12.0 0.1 7.1 6.6 0.0 3.3 3 0 0 3 3 3 0 Transglutaminase-like superfamily PPR_3 PF13812.6 KXS13620.1 - 4.1e-36 122.9 0.0 4.2e-12 46.0 0.1 6.7 6 1 1 7 7 7 5 Pentatricopeptide repeat domain PPR_2 PF13041.6 KXS13620.1 - 1.3e-33 115.0 0.2 4.1e-12 46.1 0.1 7.4 6 1 1 7 7 7 5 PPR repeat family PPR_1 PF12854.7 KXS13620.1 - 1.6e-17 62.9 2.1 0.0013 18.3 0.1 7.0 7 0 0 7 7 7 4 PPR repeat PPR PF01535.20 KXS13620.1 - 7.5e-11 41.5 5.1 0.0023 18.0 0.0 6.9 7 1 0 7 7 7 2 PPR repeat PPR_long PF17177.4 KXS13620.1 - 2.3e-09 36.9 0.3 4.1e-06 26.3 0.0 3.8 3 1 1 4 4 4 1 Pentacotripeptide-repeat region of PRORP MRP-S27 PF10037.9 KXS13620.1 - 0.0012 17.8 0.0 0.0028 16.6 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S27 TPR_4 PF07721.14 KXS13620.1 - 0.027 15.1 0.1 2.8 8.8 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF1682 PF07946.14 KXS13621.1 - 1.3e-54 185.6 0.0 1.6e-54 185.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) Ribosomal_L37 PF08561.10 KXS13621.1 - 0.31 11.6 10.7 0.49 10.9 10.1 1.6 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L37 E1-E2_ATPase PF00122.20 KXS13622.1 - 0.024 14.2 0.7 0.038 13.5 0.7 1.2 1 0 0 1 1 1 0 E1-E2 ATPase Hydrolase_3 PF08282.12 KXS13624.1 - 4.7e-42 144.5 0.0 3.1e-27 95.9 0.0 2.0 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase S6PP PF05116.13 KXS13624.1 - 2.8e-12 46.7 0.0 2.9e-08 33.6 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 KXS13624.1 - 0.0005 20.4 0.0 0.18 12.1 0.0 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 KXS13624.1 - 0.00055 20.4 0.4 1.7 9.0 0.0 3.2 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase Trehalose_PPase PF02358.16 KXS13624.1 - 0.2 10.8 0.0 0.43 9.7 0.0 1.5 2 0 0 2 2 2 0 Trehalose-phosphatase SnAC PF14619.6 KXS13625.1 - 0.00097 19.7 1.5 0.0016 19.0 0.9 1.7 1 1 0 1 1 1 1 Snf2-ATP coupling, chromatin remodelling complex TMEM70 PF06979.12 KXS13626.1 - 0.52 10.7 3.0 11 6.4 1.1 2.1 2 0 0 2 2 2 0 Assembly, mitochondrial proton-transport ATP synth complex ETF PF01012.21 KXS13628.1 - 3.4e-48 163.9 7.1 4.2e-48 163.6 7.1 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Toprim_2 PF13155.6 KXS13628.1 - 0.082 13.3 0.2 0.16 12.4 0.2 1.5 1 0 0 1 1 1 0 Toprim-like Rotamase_3 PF13616.6 KXS13629.1 - 7.5e-18 65.2 1.0 3.1e-17 63.2 1.0 2.0 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 KXS13629.1 - 1.4e-15 58.0 0.5 2.5e-15 57.2 0.5 1.7 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 KXS13629.1 - 3.1e-05 24.8 0.4 8.9e-05 23.3 0.4 1.8 1 1 0 1 1 1 1 PPIC-type PPIASE domain DUF4777 PF16007.5 KXS13629.1 - 0.026 14.8 0.0 0.043 14.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4777) Wound_ind PF08186.11 KXS13629.1 - 5.3 7.5 7.4 37 4.9 3.3 2.4 2 0 0 2 2 2 0 Wound-inducible basic protein family HSP20 PF00011.21 KXS13630.1 - 6.6e-13 48.7 0.0 3.6e-12 46.3 0.0 2.0 1 1 0 1 1 1 1 Hsp20/alpha crystallin family Phasin_2 PF09361.10 KXS13630.1 - 0.00069 19.8 14.2 0.031 14.5 10.6 2.6 1 1 0 2 2 2 2 Phasin protein ArsA_HSP20 PF17886.1 KXS13630.1 - 0.059 12.9 0.0 0.15 11.7 0.0 1.7 1 1 0 1 1 1 0 HSP20-like domain found in ArsA HSP9_HSP12 PF04119.12 KXS13630.1 - 0.71 10.3 3.0 8.9 6.8 0.0 3.0 3 0 0 3 3 3 0 Heat shock protein 9/12 DUF883 PF05957.13 KXS13630.1 - 1.4 9.6 12.7 1.3 9.7 8.4 2.8 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) Phage_holin_5_1 PF06946.11 KXS13630.1 - 2.8 8.4 8.2 4.1 7.9 0.8 3.2 3 0 0 3 3 3 0 Bacteriophage A118-like holin, Hol118 Kinesin PF00225.23 KXS13631.1 - 1.2e-103 346.6 0.0 1.5e-103 346.3 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KXS13631.1 - 2.1e-21 76.4 0.0 4.1e-21 75.5 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding RhoGEF PF00621.20 KXS13632.1 - 7.1e-29 101.3 0.0 7.8e-29 101.2 0.0 1.0 1 0 0 1 1 1 1 RhoGEF domain Chromo PF00385.24 KXS13633.1 - 0.00025 20.9 14.0 0.011 15.6 0.6 3.1 2 1 1 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain CcmD PF04995.14 KXS13637.1 - 0.004 17.2 4.0 0.004 17.2 4.0 2.0 2 0 0 2 2 2 1 Heme exporter protein D (CcmD) GCN5L1 PF06320.13 KXS13637.1 - 0.082 13.1 0.9 0.12 12.5 0.9 1.2 1 0 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) GSHPx PF00255.19 KXS13638.1 - 9.9e-45 150.6 0.1 1.2e-44 150.3 0.1 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 KXS13638.1 - 5.3e-06 26.4 0.0 1.6e-05 24.8 0.0 1.8 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KXS13638.1 - 0.0062 16.2 0.1 0.02 14.6 0.1 1.8 1 1 0 1 1 1 1 Redoxin DUF4174 PF13778.6 KXS13638.1 - 0.08 13.4 0.0 0.091 13.2 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4174) ATG_C PF09333.11 KXS13639.1 - 2.6e-34 117.4 0.6 6.3e-34 116.2 0.1 2.0 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain Chorein_N PF12624.7 KXS13639.1 - 5.3e-15 55.6 0.0 1.5e-14 54.1 0.0 1.7 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 ATG2_CAD PF13329.6 KXS13639.1 - 3.4e-13 49.6 0.2 3.4e-12 46.4 0.1 2.6 3 0 0 3 3 3 1 Autophagy-related protein 2 CAD motif VPS13_C PF16909.5 KXS13639.1 - 1.3e-08 34.8 0.0 3.1e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 Vacuolar-sorting-associated 13 protein C-terminal AAA_16 PF13191.6 KXS13640.1 - 0.011 16.1 0.4 0.52 10.7 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain EF-hand_13 PF17958.1 KXS13641.1 - 6.4e-17 61.1 0.0 3.8e-16 58.7 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 KXS13641.1 - 1.6e-11 44.5 0.0 5.3e-09 36.4 0.0 3.4 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 KXS13641.1 - 2.6e-05 23.5 0.6 0.003 17.0 0.2 3.3 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.6 KXS13641.1 - 0.00025 20.7 3.7 0.016 15.1 0.2 3.5 3 0 0 3 3 3 1 EF-hand domain EF-hand_5 PF13202.6 KXS13641.1 - 0.00025 20.4 0.0 0.00089 18.6 0.0 2.0 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 KXS13641.1 - 0.01 15.7 0.7 0.064 13.1 0.2 2.4 2 0 0 2 2 2 0 EF-hand domain pair Nipped-B_C PF12830.7 KXS13643.1 - 2.5e-40 138.4 0.8 2.8e-39 135.1 0.2 2.9 2 1 1 3 3 3 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 KXS13643.1 - 4.6e-12 46.0 5.2 1.7e-09 37.8 1.2 3.5 3 0 0 3 3 3 2 HEAT repeat associated with sister chromatid cohesion Adaptin_N PF01602.20 KXS13643.1 - 0.00043 19.0 2.4 0.39 9.2 0.1 3.4 3 1 0 3 3 3 2 Adaptin N terminal region HEAT PF02985.22 KXS13643.1 - 0.00075 19.5 8.0 1.5 9.3 0.0 6.5 7 0 0 7 7 7 1 HEAT repeat HEAT_2 PF13646.6 KXS13643.1 - 0.0044 17.4 5.3 0.4 11.1 0.0 5.0 5 1 0 5 5 5 1 HEAT repeats Cnd1 PF12717.7 KXS13643.1 - 0.036 14.1 0.2 2.2 8.3 0.0 3.4 2 1 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 HHV-5_US34A PF17087.5 KXS13643.1 - 0.076 13.2 0.0 0.29 11.3 0.0 2.1 1 0 0 1 1 1 0 Herpesvirus US34A protein family HEAT_EZ PF13513.6 KXS13643.1 - 1.2 9.8 7.2 1.1e+02 3.4 0.0 5.3 5 0 0 5 5 5 0 HEAT-like repeat PBP1_TM PF14812.6 KXS13643.1 - 8.7 6.8 12.7 0.79 10.1 7.2 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal HLH PF00010.26 KXS13644.1 - 1.3e-08 34.7 0.1 1.3e-08 34.7 0.1 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain DUF3530 PF12048.8 KXS13644.1 - 0.16 11.4 0.1 0.16 11.4 0.1 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3530) Hydrolase_4 PF12146.8 KXS13645.1 - 1.5e-20 73.5 0.0 2.1e-20 73.0 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KXS13645.1 - 4.3e-12 47.1 4.7 6.3e-12 46.6 4.7 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXS13645.1 - 5.8e-07 29.4 0.1 1.4e-06 28.1 0.1 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold PPS_PS PF02006.16 KXS13645.1 - 0.13 11.8 0.0 2 7.9 0.0 2.1 2 0 0 2 2 2 0 Phosphopantothenate/pantothenate synthetase Methyltransf_23 PF13489.6 KXS13646.1 - 1.9e-07 31.1 0.0 2.3e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXS13646.1 - 4.2e-06 27.4 0.0 8.5e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXS13646.1 - 1.8e-05 25.4 0.0 3.8e-05 24.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXS13646.1 - 0.00016 22.2 0.0 0.00031 21.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_28 PF02636.17 KXS13646.1 - 0.00031 20.5 0.0 0.00063 19.4 0.0 1.4 2 0 0 2 2 2 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PCMT PF01135.19 KXS13646.1 - 0.017 14.9 0.0 0.027 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 KXS13646.1 - 0.02 14.9 0.0 0.029 14.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Botulinum_HA-17 PF05588.11 KXS13647.1 - 0.042 14.0 0.1 0.092 12.9 0.1 1.5 1 1 0 1 1 1 0 Clostridium botulinum HA-17 domain YL1_C PF08265.11 KXS13649.1 - 3.9e-15 55.3 0.5 7.6e-15 54.4 0.1 1.7 2 0 0 2 2 2 1 YL1 nuclear protein C-terminal domain zf-HIT PF04438.16 KXS13649.1 - 0.1 12.5 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 HIT zinc finger AMP-binding PF00501.28 KXS13652.1 - 1.3e-71 241.4 0.0 3e-71 240.2 0.0 1.5 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXS13652.1 - 1.7e-22 80.1 0.0 2.9e-21 76.2 0.1 3.0 3 1 0 3 3 3 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 KXS13652.1 - 4.6e-17 61.7 1.5 9.9e-17 60.6 1.5 1.6 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus RXT2_N PF08595.11 KXS13654.1 - 4.9e-09 36.4 0.0 2.7e-07 30.8 0.0 2.3 1 1 1 2 2 2 2 RXT2-like, N-terminal BCA_ABC_TP_C PF12399.8 KXS13654.1 - 0.016 15.1 0.1 0.13 12.2 0.3 2.3 2 0 0 2 2 2 0 Branched-chain amino acid ATP-binding cassette transporter HEAT_EZ PF13513.6 KXS13655.1 - 3.8e-28 97.5 13.3 1.9e-07 31.4 0.0 9.9 7 2 3 10 10 9 7 HEAT-like repeat Importin_rep_4 PF18808.1 KXS13655.1 - 1.1e-20 73.7 0.1 1.1e-20 73.7 0.1 4.1 5 0 0 5 5 4 1 Importin repeat HEAT PF02985.22 KXS13655.1 - 1.3e-19 68.6 19.6 3.4e-06 26.8 0.0 11.7 13 0 0 13 13 11 4 HEAT repeat HEAT_2 PF13646.6 KXS13655.1 - 9.1e-17 61.2 8.1 0.00025 21.4 0.0 8.5 4 2 3 7 7 7 3 HEAT repeats Importin_rep_6 PF18829.1 KXS13655.1 - 7e-13 48.7 0.6 7e-13 48.7 0.6 3.6 5 0 0 5 5 4 1 Importin repeat 6 Vac14_Fab1_bd PF12755.7 KXS13655.1 - 7.7e-13 48.9 0.1 1.7e-05 25.3 0.0 6.9 4 2 4 8 8 7 1 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 KXS13655.1 - 3.2e-08 32.6 0.8 0.00072 18.2 0.1 3.8 4 0 0 4 4 4 2 Adaptin N terminal region CLASP_N PF12348.8 KXS13655.1 - 7e-08 32.3 0.0 0.79 9.2 0.0 6.4 5 2 1 6 6 6 2 CLASP N terminal RIX1 PF08167.12 KXS13655.1 - 6.8e-07 29.2 0.2 0.044 13.5 0.0 4.5 3 2 1 4 4 4 2 rRNA processing/ribosome biogenesis Cnd1 PF12717.7 KXS13655.1 - 8.1e-07 29.2 0.7 0.0014 18.7 0.0 4.4 5 1 0 5 5 4 1 non-SMC mitotic condensation complex subunit 1 MMS19_C PF12460.8 KXS13655.1 - 8.4e-06 25.2 1.1 0.36 9.9 0.1 4.6 4 1 1 5 5 5 2 RNAPII transcription regulator C-terminal Arm PF00514.23 KXS13655.1 - 1e-05 25.4 6.6 0.52 10.4 0.0 6.2 7 0 0 7 7 5 2 Armadillo/beta-catenin-like repeat Cohesin_HEAT PF12765.7 KXS13655.1 - 4e-05 23.8 0.0 1.2 9.5 0.0 4.1 4 0 0 4 4 3 1 HEAT repeat associated with sister chromatid cohesion RTP1_C1 PF10363.9 KXS13655.1 - 5.8e-05 23.3 0.0 3.6 7.8 0.0 5.2 5 2 2 7 7 7 1 Required for nuclear transport of RNA pol II C-terminus 1 DUF3385 PF11865.8 KXS13655.1 - 0.00048 20.1 0.1 0.87 9.5 0.0 5.3 4 1 1 5 5 5 2 Domain of unknown function (DUF3385) UME PF08064.13 KXS13655.1 - 0.0019 18.1 0.0 7.9 6.5 0.0 4.0 4 0 0 4 4 4 0 UME (NUC010) domain DUF4042 PF13251.6 KXS13655.1 - 0.0023 17.6 0.1 0.43 10.3 0.0 3.8 4 0 0 4 4 4 1 Domain of unknown function (DUF4042) Importin_rep_5 PF18816.1 KXS13655.1 - 0.0036 17.6 0.0 0.011 16.0 0.0 1.8 1 0 0 1 1 1 1 Importin repeat DUF5071 PF16804.5 KXS13655.1 - 0.0037 17.5 2.1 10 6.4 0.0 4.6 4 0 0 4 4 4 0 Domain of unknown function (DUF5071) V-ATPase_H_C PF11698.8 KXS13655.1 - 0.011 15.8 0.1 16 5.6 0.0 3.6 3 0 0 3 3 3 0 V-ATPase subunit H ParcG PF10274.9 KXS13655.1 - 0.057 13.5 0.1 0.75 9.9 0.1 2.9 3 0 0 3 3 2 0 Parkin co-regulated protein Cnd3 PF12719.7 KXS13655.1 - 0.082 12.1 0.3 2.1 7.5 0.0 3.2 4 0 0 4 4 4 0 Nuclear condensing complex subunits, C-term domain V-ATPase_H_N PF03224.14 KXS13655.1 - 0.14 11.4 0.1 4.8 6.4 0.1 2.8 3 0 0 3 3 3 0 V-ATPase subunit H ING PF12998.7 KXS13657.1 - 2.9e-20 72.7 0.7 5.3e-20 71.9 0.7 1.4 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 KXS13657.1 - 7.2e-06 25.8 7.2 1.2e-05 25.1 7.2 1.4 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 KXS13657.1 - 0.019 15.2 0.7 0.019 15.2 0.7 1.8 1 1 1 2 2 2 0 PHD-like zinc-binding domain PHD_2 PF13831.6 KXS13657.1 - 0.034 13.7 3.0 0.066 12.8 3.0 1.4 1 0 0 1 1 1 0 PHD-finger FAM76 PF16046.5 KXS13657.1 - 0.047 13.0 2.1 0.062 12.6 0.3 1.9 2 0 0 2 2 2 0 FAM76 protein zf-RING_2 PF13639.6 KXS13657.1 - 3.5 8.0 7.2 6.2 7.2 7.2 1.4 1 0 0 1 1 1 0 Ring finger domain DNA_topoisoIV PF00521.20 KXS13658.1 - 8.3e-125 417.0 0.4 4.1e-124 414.7 0.4 2.1 1 1 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 KXS13658.1 - 2.5e-51 173.3 0.3 2.5e-51 173.3 0.3 2.2 2 0 0 2 2 2 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 KXS13658.1 - 9.1e-28 96.9 1.8 1.6e-27 96.1 0.4 2.0 2 0 0 2 2 2 1 DNA gyrase B HATPase_c PF02518.26 KXS13658.1 - 1.3e-13 51.5 0.0 3.5e-13 50.0 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 KXS13658.1 - 7e-10 39.1 0.0 4.5e-08 33.3 0.0 2.7 2 0 0 2 2 2 1 Toprim domain TFIIS_M PF07500.14 KXS13658.1 - 0.0031 18.0 2.0 0.027 14.9 0.1 3.2 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS), central domain GatB_Yqey PF02637.18 KXS13658.1 - 0.011 15.6 2.4 0.029 14.3 0.2 2.5 2 0 0 2 2 2 0 GatB domain DUF4467 PF14729.6 KXS13658.1 - 0.59 10.5 2.8 0.57 10.6 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function with cystatin-like fold (DUF4467) Sacchrp_dh_C PF16653.5 KXS13659.1 - 7.7e-89 298.3 0.0 2.4e-88 296.7 0.0 1.7 1 1 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 KXS13659.1 - 7e-26 91.0 0.0 1e-25 90.5 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 KXS13659.1 - 1.5e-05 24.9 0.0 2.4e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Shikimate_DH PF01488.20 KXS13659.1 - 1.8e-05 24.8 0.0 0.00017 21.7 0.0 2.0 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_3 PF03447.16 KXS13659.1 - 0.0014 19.2 0.0 0.0027 18.4 0.0 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 KXS13659.1 - 0.036 14.9 0.1 0.072 13.9 0.1 1.5 1 1 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.24 KXS13659.1 - 0.085 13.3 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 KXS13659.1 - 0.14 12.6 0.0 0.26 11.7 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Na_K-ATPase PF00287.18 KXS13660.1 - 0.043 13.0 0.1 0.066 12.4 0.1 1.2 1 0 0 1 1 1 0 Sodium / potassium ATPase beta chain DUF5325 PF17259.2 KXS13660.1 - 0.25 11.2 0.1 0.25 11.2 0.1 3.0 4 0 0 4 4 4 0 Family of unknown function (DUF5325) DUF5337 PF17272.2 KXS13660.1 - 3.5 7.5 7.6 0.3 10.9 1.4 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5337) Ring_hydroxyl_A PF00848.19 KXS13661.1 - 5.5e-27 95.1 0.0 9.4e-27 94.4 0.0 1.3 1 0 0 1 1 1 1 Ring hydroxylating alpha subunit (catalytic domain) Complex1_49kDa PF00346.19 KXS13661.1 - 0.0068 15.5 0.0 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit Imm35 PF15567.6 KXS13661.1 - 0.04 14.1 0.0 0.079 13.1 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 35 DUF3016 PF11454.8 KXS13661.1 - 0.17 11.6 0.0 0.36 10.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3016) DUF2070 PF09843.9 KXS13663.1 - 0.035 12.4 1.6 0.038 12.3 1.6 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) LRR_8 PF13855.6 KXS13665.1 - 3.9e-22 77.8 10.5 7.5e-11 41.6 0.5 4.6 4 1 1 5 5 5 3 Leucine rich repeat LRR_4 PF12799.7 KXS13665.1 - 7.4e-19 67.5 5.4 4.3e-05 23.8 0.1 5.4 5 1 1 6 6 6 5 Leucine Rich repeats (2 copies) SH3_9 PF14604.6 KXS13665.1 - 7.6e-11 41.7 0.0 1.7e-10 40.6 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain LRR_1 PF00560.33 KXS13665.1 - 2.2e-07 30.4 1.1 1.2 10.0 0.1 7.0 8 0 0 8 8 8 2 Leucine Rich Repeat SH3_1 PF00018.28 KXS13665.1 - 7.7e-07 28.6 0.0 1.3e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KXS13665.1 - 0.00093 18.8 0.0 0.0018 17.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain LRR_6 PF13516.6 KXS13665.1 - 0.0017 18.2 4.6 3.9 7.8 0.0 5.7 6 0 0 6 6 6 1 Leucine Rich repeat LRR_9 PF14580.6 KXS13665.1 - 0.057 12.9 0.2 1.3 8.5 0.1 2.5 1 1 1 3 3 3 0 Leucine-rich repeat SKG6 PF08693.10 KXS13665.1 - 0.32 10.5 2.0 0.6 9.6 2.0 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain VSP PF03302.13 KXS13665.1 - 9 5.0 9.5 22 3.8 9.5 1.6 1 1 0 1 1 1 0 Giardia variant-specific surface protein SHS2_Rpb7-N PF03876.17 KXS13666.1 - 1.2e-12 48.0 0.0 2e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 KXS13666.1 - 8.8e-08 32.4 0.0 1.7e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.12 KXS13666.1 - 0.038 14.2 0.0 0.058 13.6 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase III subunit Rpc25 IFT43 PF15305.6 KXS13667.1 - 0.00093 19.4 10.7 0.0099 16.1 10.7 2.0 1 1 0 1 1 1 1 Intraflagellar transport protein 43 EF1G PF00647.19 KXS13668.1 - 7.1e-47 157.9 0.3 1.4e-46 157.0 0.3 1.5 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_N PF02798.20 KXS13668.1 - 1.5e-16 60.5 0.0 4.9e-16 58.8 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KXS13668.1 - 1e-12 48.1 0.1 1e-12 48.1 0.1 2.5 2 1 0 2 2 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KXS13668.1 - 4.8e-07 30.1 0.1 2.7e-06 27.7 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KXS13668.1 - 6.8e-06 26.2 0.0 6.8e-06 26.2 0.0 2.4 3 0 0 3 3 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KXS13668.1 - 3.6e-05 23.7 0.0 8.9e-05 22.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KXS13668.1 - 0.001 19.3 0.0 0.0026 18.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 KXS13668.1 - 0.011 15.5 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain CPSF100_C PF13299.6 KXS13668.1 - 0.037 14.2 5.3 0.069 13.3 5.3 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal ORC_WH_C PF18137.1 KXS13668.1 - 0.064 13.3 1.3 0.12 12.4 1.3 1.4 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal DUF913 PF06025.12 KXS13668.1 - 0.27 10.2 0.6 0.38 9.7 0.6 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) RR_TM4-6 PF06459.12 KXS13668.1 - 0.41 10.4 10.1 0.57 10.0 10.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.14 KXS13668.1 - 0.67 8.2 4.9 0.89 7.8 4.9 1.1 1 0 0 1 1 1 0 CDC45-like protein RNA_pol_Rpc4 PF05132.14 KXS13668.1 - 0.71 10.3 9.0 1.2 9.6 9.0 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 NARP1 PF12569.8 KXS13668.1 - 1.5 7.6 10.6 2.2 7.1 10.6 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 FGF-BP1 PF06473.12 KXS13668.1 - 1.7 8.4 11.3 2.5 7.9 11.3 1.1 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) SpoIIP PF07454.11 KXS13668.1 - 3.7 6.9 8.1 5.5 6.4 8.1 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) GAGA_bind PF06217.12 KXS13668.1 - 3.8 7.7 9.2 5.6 7.2 9.2 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family Tim54 PF11711.8 KXS13668.1 - 3.8 6.2 12.6 5.5 5.7 12.6 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 NPL4 PF05021.15 KXS13669.1 - 1.3e-120 402.5 0.0 1.6e-120 402.1 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.15 KXS13669.1 - 1.3e-62 210.2 0.0 2e-62 209.6 0.0 1.3 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.8 KXS13669.1 - 2.2e-11 44.1 0.0 4.5e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 zf-RanBP PF00641.18 KXS13669.1 - 0.00011 21.4 1.4 0.00011 21.4 1.4 1.9 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others Ephrin_rec_like PF07699.13 KXS13669.1 - 8.9 6.2 8.5 0.15 11.8 0.5 2.3 2 1 0 2 2 2 0 Putative ephrin-receptor like RIO1 PF01163.22 KXS13670.1 - 2e-49 167.8 0.0 2.9e-49 167.2 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.11 KXS13670.1 - 3.2e-34 117.0 0.4 6.3e-34 116.0 0.2 1.6 2 0 0 2 2 2 1 Rio2, N-terminal APH PF01636.23 KXS13670.1 - 2.2e-13 50.7 3.6 3.4e-07 30.4 0.3 2.7 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KXS13670.1 - 1.6e-07 30.9 0.2 9.1e-06 25.2 0.1 2.5 2 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KXS13670.1 - 0.082 12.2 0.1 0.61 9.3 0.0 2.0 2 0 0 2 2 2 0 Kinase-like APH_6_hur PF04655.14 KXS13670.1 - 0.13 11.7 0.0 2.5 7.4 0.0 2.2 2 0 0 2 2 2 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase Nkap_C PF06047.11 KXS13671.1 - 1.9e-47 159.6 6.3 3.6e-47 158.7 6.3 1.5 1 0 0 1 1 1 1 NF-kappa-B-activating protein C-terminal domain Zip PF02535.22 KXS13671.1 - 1.2 8.3 6.0 1.6 7.9 6.0 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Ribosomal_L35Ae PF01247.18 KXS13672.1 - 1.4e-41 140.5 0.2 1.6e-41 140.4 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 KXS13672.1 - 0.09 13.0 0.0 3.5 7.9 0.0 2.1 2 0 0 2 2 2 0 RimM N-terminal domain FmiP_Thoc5 PF09766.9 KXS13673.1 - 5.7e-58 197.0 8.3 1.4e-39 136.5 8.5 2.9 2 1 1 3 3 3 2 Fms-interacting protein/Thoc5 DUF1043 PF06295.12 KXS13673.1 - 0.091 12.8 2.6 1.7 8.7 2.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) APG6_N PF17675.1 KXS13673.1 - 0.25 11.9 20.7 2.8 8.5 2.0 2.4 1 1 1 2 2 2 0 Apg6 coiled-coil region OmpH PF03938.14 KXS13673.1 - 0.57 10.5 8.1 0.11 12.8 3.5 1.9 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) WDCP PF15390.6 KXS13673.1 - 1.6 7.1 3.0 2.1 6.6 3.0 1.1 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family Spc24 PF08286.11 KXS13673.1 - 2 8.7 6.1 0.21 11.8 1.1 1.9 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 LSM PF01423.22 KXS13674.1 - 5.7e-22 77.2 0.1 6.4e-22 77.0 0.1 1.1 1 0 0 1 1 1 1 LSM domain DUF150_C PF17384.2 KXS13674.1 - 0.12 12.5 0.0 0.15 12.2 0.0 1.2 1 0 0 1 1 1 0 RimP C-terminal SH3 domain Hfq PF17209.3 KXS13674.1 - 0.15 11.7 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 Hfq protein Ribosomal_L26 PF16906.5 KXS13675.1 - 1.4e-39 134.4 3.9 1.9e-39 134.0 3.9 1.2 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 KXS13675.1 - 2.1e-07 30.7 4.0 5.5e-07 29.3 4.0 1.7 1 0 0 1 1 1 1 KOW motif Musclin PF11037.8 KXS13675.1 - 0.038 13.9 1.1 0.062 13.2 1.1 1.5 1 1 0 1 1 1 0 Insulin-resistance promoting peptide in skeletal muscle ASF1_hist_chap PF04729.13 KXS13676.1 - 2.9e-71 238.4 0.2 3.3e-71 238.2 0.2 1.0 1 0 0 1 1 1 1 ASF1 like histone chaperone DUF4148 PF13663.6 KXS13678.1 - 0.2 11.8 0.3 0.29 11.3 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) APG6 PF04111.12 KXS13679.1 - 3.4e-68 229.1 0.0 5.1e-68 228.5 0.0 1.3 1 0 0 1 1 1 1 Apg6 BARA domain APG6_N PF17675.1 KXS13679.1 - 5e-28 98.3 15.9 8.5e-28 97.5 15.9 1.4 1 0 0 1 1 1 1 Apg6 coiled-coil region BH3 PF15285.6 KXS13679.1 - 5e-05 23.0 0.3 0.00011 21.9 0.3 1.5 1 0 0 1 1 1 1 Beclin-1 BH3 domain, Bcl-2-interacting DUF4698 PF15769.5 KXS13679.1 - 0.35 9.9 5.6 0.47 9.4 5.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4698) GAS PF13851.6 KXS13679.1 - 0.36 10.1 9.8 0.063 12.6 5.6 1.8 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF1843 PF08898.10 KXS13679.1 - 2.3 8.8 8.6 2.4 8.7 5.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) zf-HYPF PF07503.12 KXS13679.1 - 2.4 8.0 4.2 2.8 7.8 0.5 2.4 2 0 0 2 2 2 0 HypF finger DUF4530 PF15039.6 KXS13679.1 - 3.4 7.9 7.2 6.4 7.0 6.5 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4530) zf-CCCH PF00642.24 KXS13680.1 - 6.1e-12 45.1 33.9 0.0028 17.5 0.1 5.3 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3H1 PF10650.9 KXS13680.1 - 0.00024 20.7 7.0 0.081 12.7 0.4 3.9 4 0 0 4 4 4 2 Putative zinc-finger domain zf_CCCH_4 PF18345.1 KXS13680.1 - 0.0068 16.4 32.0 0.13 12.3 0.7 6.3 5 2 0 5 5 5 3 Zinc finger domain zf-CCCH_3 PF15663.5 KXS13680.1 - 0.023 14.9 2.3 0.023 14.9 2.3 3.4 1 1 2 3 3 3 0 Zinc-finger containing family Torus PF16131.5 KXS13680.1 - 0.18 12.5 23.3 0.78 10.5 0.1 4.8 1 1 4 5 5 5 0 Torus domain eIF-1a PF01176.19 KXS13681.1 - 1.9e-18 66.0 0.2 3.1e-18 65.3 0.2 1.4 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Pkinase PF00069.25 KXS13683.1 - 2.4e-66 223.8 0.0 3.2e-66 223.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS13683.1 - 6.7e-33 114.1 0.0 1.1e-32 113.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXS13683.1 - 2.8e-05 23.6 1.3 0.023 14.0 0.1 2.4 2 1 1 3 3 3 2 Kinase-like Haspin_kinase PF12330.8 KXS13683.1 - 0.0073 15.3 0.0 0.065 12.2 0.0 2.0 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KXS13683.1 - 0.029 13.7 0.0 0.051 12.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXS13683.1 - 0.037 14.0 0.0 0.088 12.7 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family AdoHcyase PF05221.17 KXS13683.1 - 0.07 12.3 0.1 0.11 11.7 0.1 1.2 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase DUF1325 PF07039.11 KXS13684.1 - 1.2e-25 90.1 0.0 2.1e-25 89.3 0.0 1.4 1 0 0 1 1 1 1 SGF29 tudor-like domain Tudor_3 PF18115.1 KXS13684.1 - 0.00038 20.3 0.0 0.00084 19.1 0.0 1.6 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain TUDOR_5 PF18359.1 KXS13684.1 - 0.017 14.8 0.0 0.033 13.9 0.0 1.4 1 0 0 1 1 1 0 Histone methyltransferase Tudor domain 1 RPN6_N PF18055.1 KXS13685.1 - 8.2e-34 116.5 0.2 3.6e-33 114.4 0.0 2.1 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 KXS13685.1 - 4.8e-19 68.8 0.8 1.6e-18 67.1 0.2 2.2 2 0 0 2 2 2 1 PCI domain RPN6_C_helix PF18503.1 KXS13685.1 - 1.5e-13 50.2 0.5 4e-13 48.8 0.5 1.8 1 0 0 1 1 1 1 26S proteasome subunit RPN6 C-terminal helix domain TPR_MalT PF17874.1 KXS13685.1 - 0.00097 18.6 0.9 0.009 15.4 0.4 2.1 2 0 0 2 2 2 1 MalT-like TPR region DDRGK PF09756.9 KXS13685.1 - 0.059 13.0 0.1 0.1 12.2 0.1 1.3 1 0 0 1 1 1 0 DDRGK domain Vps39_1 PF10366.9 KXS13685.1 - 0.088 13.1 1.2 0.23 11.8 0.4 2.1 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 TPR_12 PF13424.6 KXS13685.1 - 0.38 11.1 6.2 3.6 8.0 1.2 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 KXS13685.1 - 2.1 8.9 5.3 35 5.0 0.2 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat zf_CCCH_4 PF18345.1 KXS13686.1 - 1.4e-16 60.0 51.9 8.7e-07 28.8 2.0 6.3 6 1 0 6 6 6 4 Zinc finger domain zf-CCCH PF00642.24 KXS13686.1 - 1e-15 57.2 38.9 6.6e-06 25.9 0.6 5.4 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 KXS13686.1 - 8.5e-12 45.7 27.4 0.00014 22.5 0.5 5.3 1 1 4 5 5 5 5 Torus domain zf-CCCH_4 PF18044.1 KXS13686.1 - 4.2e-09 36.0 7.3 1.8e-05 24.4 0.4 5.7 5 1 0 5 5 5 2 CCCH-type zinc finger zf-CCCH_3 PF15663.5 KXS13686.1 - 1.2e-08 35.1 23.3 3.7e-07 30.3 8.5 3.8 1 1 2 3 3 3 2 Zinc-finger containing family zf-CCCH_2 PF14608.6 KXS13686.1 - 1.3e-07 31.8 46.0 0.031 14.7 1.2 6.0 6 0 0 6 6 6 5 RNA-binding, Nab2-type zinc finger zf-CCHC PF00098.23 KXS13686.1 - 2.6e-06 27.2 2.6 2.6e-06 27.2 2.6 3.4 3 0 0 3 3 3 1 Zinc knuckle CRAM_rpt PF07016.11 KXS13686.1 - 3.4 7.6 7.6 21 5.1 0.0 4.1 4 0 0 4 4 4 0 Cysteine-rich acidic integral membrane protein precursor Ribosomal_S6 PF01250.17 KXS13687.1 - 3.2e-19 69.0 0.0 3.6e-19 68.8 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S6 Helicase_C_2 PF13307.6 KXS13688.1 - 3.9e-56 189.9 0.2 3.4e-55 186.8 0.0 2.5 3 1 0 3 3 3 1 Helicase C-terminal domain DEAD_2 PF06733.15 KXS13688.1 - 2.1e-47 161.0 0.0 3.8e-47 160.2 0.0 1.4 1 0 0 1 1 1 1 DEAD_2 DEAD PF00270.29 KXS13688.1 - 0.00015 21.6 0.0 0.011 15.4 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase PhoH PF02562.16 KXS13688.1 - 0.00015 21.3 0.1 0.0055 16.2 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein ResIII PF04851.15 KXS13688.1 - 0.00029 20.9 1.5 0.051 13.6 0.1 2.8 2 2 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KXS13688.1 - 0.033 14.5 0.3 18 5.6 0.0 3.6 4 0 0 4 4 4 0 AAA domain ArsA_ATPase PF02374.15 KXS13689.1 - 3.2e-115 384.5 0.4 3.7e-115 384.3 0.4 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 KXS13689.1 - 2.6e-14 53.6 0.1 1.2e-13 51.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain CbiA PF01656.23 KXS13689.1 - 1.8e-12 47.4 0.0 8.1e-12 45.3 0.0 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Fer4_NifH PF00142.18 KXS13689.1 - 1.2e-05 24.9 0.0 2.7e-05 23.7 0.0 1.7 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ParA PF10609.9 KXS13689.1 - 2e-05 24.2 3.1 0.00012 21.6 0.4 2.4 2 1 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase SRP54 PF00448.22 KXS13689.1 - 3e-05 23.8 1.2 0.0017 18.0 0.4 2.5 1 1 1 2 2 2 1 SRP54-type protein, GTPase domain CBP_BcsQ PF06564.12 KXS13689.1 - 0.00012 21.6 0.1 0.00032 20.3 0.0 1.6 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ AAA_18 PF13238.6 KXS13689.1 - 0.0036 17.8 0.0 0.012 16.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KXS13689.1 - 0.012 15.0 0.0 0.021 14.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_24 PF13479.6 KXS13689.1 - 0.015 15.0 0.0 0.054 13.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 KXS13689.1 - 0.03 13.9 2.5 0.28 10.8 2.5 2.2 1 1 0 1 1 1 0 AAA domain Elf1 PF05129.13 KXS13689.1 - 0.051 13.6 0.0 0.098 12.7 0.0 1.4 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like MeaB PF03308.16 KXS13689.1 - 0.052 12.5 0.1 5.5 5.9 0.0 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RNA_helicase PF00910.22 KXS13689.1 - 0.055 13.9 1.0 0.85 10.0 0.2 3.0 2 2 1 3 3 3 0 RNA helicase CobA_CobO_BtuR PF02572.15 KXS13689.1 - 0.099 12.9 2.2 18 5.5 0.8 3.2 2 1 0 2 2 2 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP NB-ARC PF00931.22 KXS13689.1 - 0.1 11.8 0.2 0.28 10.4 0.1 1.7 2 0 0 2 2 2 0 NB-ARC domain AAA PF00004.29 KXS13689.1 - 0.17 12.3 0.8 4.9 7.6 0.2 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Nop14 PF04147.12 KXS13690.1 - 5.6e-148 494.7 6.0 1.2e-118 397.6 0.4 2.1 1 1 1 2 2 2 2 Nop14-like family DEC-1_N PF04625.13 KXS13690.1 - 0.2 10.6 4.4 0.31 10.0 2.6 2.0 2 0 0 2 2 2 0 DEC-1 protein, N-terminal region Metallophos PF00149.28 KXS13692.1 - 9.4e-37 127.5 0.6 1.5e-36 126.8 0.5 1.4 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KXS13692.1 - 0.0024 18.2 0.0 0.0055 17.1 0.0 1.6 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain PARP PF00644.20 KXS13693.1 - 7.7e-57 192.0 0.1 3.4e-56 189.9 0.0 2.1 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 KXS13693.1 - 5.4e-48 162.5 0.9 1.5e-47 161.1 0.4 1.9 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 KXS13693.1 - 3.2e-29 100.8 2.8 3.2e-29 100.8 2.8 2.1 2 0 0 2 2 2 1 WGR domain BRCT PF00533.26 KXS13693.1 - 4.9e-13 49.3 0.0 2.1e-12 47.2 0.0 2.1 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KXS13693.1 - 1.9e-10 41.0 0.0 3.9e-10 40.0 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 KXS13693.1 - 3.7e-06 26.8 0.0 7.6e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain Arrestin_C PF02752.22 KXS13693.1 - 0.19 12.2 0.3 1 9.8 0.0 2.1 2 0 0 2 2 2 0 Arrestin (or S-antigen), C-terminal domain SUI1 PF01253.22 KXS13694.1 - 3.2e-22 78.8 0.0 5.6e-22 78.1 0.0 1.4 1 0 0 1 1 1 1 Translation initiation factor SUI1 BAR_2 PF10455.9 KXS13694.1 - 0.031 13.4 0.4 0.037 13.2 0.4 1.1 1 0 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking zf-C2H2 PF00096.26 KXS13695.1 - 0.0027 18.1 0.7 0.0054 17.1 0.7 1.6 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXS13695.1 - 0.017 15.9 0.3 0.035 15.0 0.3 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger zf-ribbon_3 PF13248.6 KXS13695.1 - 0.032 13.6 0.1 0.051 13.0 0.1 1.4 1 0 0 1 1 1 0 zinc-ribbon domain zf_UBZ PF18439.1 KXS13695.1 - 0.083 12.5 0.1 0.13 11.9 0.1 1.3 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger DUF2225 PF09986.9 KXS13695.1 - 0.41 10.3 0.6 0.5 10.1 0.6 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) adh_short_C2 PF13561.6 KXS13697.1 - 6.1e-54 183.0 3.5 7.3e-54 182.8 3.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXS13697.1 - 1.1e-42 145.7 3.0 1.5e-42 145.3 3.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXS13697.1 - 5.8e-07 29.6 1.2 1e-06 28.8 1.2 1.3 1 0 0 1 1 1 1 KR domain UDG PF03167.19 KXS13698.1 - 1.2e-23 83.9 0.0 1.7e-23 83.4 0.0 1.2 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily LRR_8 PF13855.6 KXS13700.1 - 3e-19 68.5 11.5 6e-07 29.1 1.4 4.3 3 1 2 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 KXS13700.1 - 3.4e-17 62.3 11.5 0.0001 22.6 2.0 4.6 3 1 1 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KXS13700.1 - 1.7e-06 27.7 5.0 7.5 7.5 0.1 7.6 9 0 0 9 9 9 1 Leucine Rich Repeat LRR_9 PF14580.6 KXS13700.1 - 0.0002 20.9 0.2 0.00078 19.0 0.0 2.0 2 1 1 3 3 3 1 Leucine-rich repeat LRR_6 PF13516.6 KXS13700.1 - 0.0044 17.0 12.8 14 6.0 0.1 7.1 7 0 0 7 7 7 1 Leucine Rich repeat TB2_DP1_HVA22 PF03134.19 KXS13701.1 - 1.6e-05 24.8 0.0 2.7e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Meth_synt_2 PF01717.18 KXS13704.1 - 8.7e-14 51.5 0.0 2.5e-13 50.0 0.0 1.7 1 1 0 1 1 1 1 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 KXS13704.1 - 0.0078 15.8 0.0 0.018 14.5 0.0 1.6 1 1 0 1 1 1 1 Cobalamin-independent synthase, N-terminal domain URO-D PF01208.17 KXS13704.1 - 0.03 13.5 0.0 0.11 11.7 0.0 1.7 1 1 0 1 1 1 0 Uroporphyrinogen decarboxylase (URO-D) G-alpha PF00503.20 KXS13706.1 - 1.9e-54 185.2 4.2 8e-43 146.9 1.2 2.4 1 1 0 2 2 2 2 G-protein alpha subunit Arf PF00025.21 KXS13706.1 - 4.9e-16 58.7 0.0 1.8e-12 47.0 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KXS13706.1 - 0.00014 21.3 0.0 0.00027 20.4 0.0 1.5 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KXS13706.1 - 0.026 14.1 0.0 0.27 10.8 0.0 2.1 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain 2OG-FeII_Oxy_3 PF13640.6 KXS13707.1 - 2.5e-12 47.5 0.0 5.2e-12 46.5 0.0 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF1757 PF08560.10 KXS13708.1 - 3e-11 43.6 0.0 5.1e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1757) DUF456 PF04306.13 KXS13708.1 - 0.023 15.0 1.1 0.023 15.0 1.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF456) FAD_binding_3 PF01494.19 KXS13709.1 - 8.3e-05 22.0 0.0 0.0002 20.8 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain FTR1 PF03239.14 KXS13712.1 - 1.9e-25 89.7 0.0 7.8e-10 38.4 0.0 3.8 1 1 2 3 3 3 3 Iron permease FTR1 family Cu-oxidase_2 PF07731.14 KXS13713.1 - 2.9e-41 140.4 0.9 8.7e-39 132.4 0.0 3.1 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KXS13713.1 - 2.7e-36 124.2 5.4 3.9e-31 107.5 0.8 3.6 4 1 1 5 5 5 2 Multicopper oxidase Cu-oxidase PF00394.22 KXS13713.1 - 1.2e-35 123.0 0.2 1.4e-31 109.7 0.1 2.7 3 0 0 3 3 3 2 Multicopper oxidase Cupredoxin_1 PF13473.6 KXS13713.1 - 0.0055 16.8 0.0 0.062 13.4 0.0 2.7 2 1 0 2 2 2 1 Cupredoxin-like domain FH2 PF02181.23 KXS13715.1 - 3.5e-86 289.6 0.2 3.5e-86 289.6 0.2 2.1 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.13 KXS13715.1 - 2.7e-21 76.0 9.8 1e-11 44.8 0.0 3.7 4 1 0 4 4 4 2 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 KXS13715.1 - 5.6e-17 62.0 6.2 2.6e-16 59.8 0.0 3.1 3 0 0 3 3 3 1 Diaphanous FH3 Domain CENP-B_dimeris PF09026.10 KXS13715.1 - 0.037 14.4 12.3 0.1 13.0 12.3 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Spore_coat_CotO PF14153.6 KXS13715.1 - 1.6 8.7 5.3 0.83 9.6 0.1 2.6 2 0 0 2 2 2 0 Spore coat protein CotO Abhydrolase_3 PF07859.13 KXS13716.1 - 2.6e-32 112.4 0.1 1.1e-24 87.5 0.1 2.6 2 0 0 2 2 2 2 alpha/beta hydrolase fold Pro_isomerase PF00160.21 KXS13717.1 - 1.4e-31 109.9 0.0 2.6e-31 109.1 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 KXS13717.1 - 2.9e-14 52.6 0.1 5.7e-14 51.7 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KXS13717.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C2H2_4 PF13894.6 KXS13719.1 - 4.8e-05 23.8 0.6 0.00011 22.8 0.6 1.6 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2 PF00096.26 KXS13719.1 - 0.00023 21.4 0.6 0.0005 20.4 0.6 1.6 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-met PF12874.7 KXS13719.1 - 0.0021 18.4 0.0 0.0041 17.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KXS13719.1 - 0.0082 16.4 0.1 0.015 15.5 0.1 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-MYST PF17772.1 KXS13719.1 - 0.026 14.1 0.2 0.041 13.5 0.2 1.3 1 0 0 1 1 1 0 MYST family zinc finger domain zf-Di19 PF05605.12 KXS13719.1 - 0.039 14.3 0.2 0.062 13.6 0.2 1.3 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding DUF2225 PF09986.9 KXS13719.1 - 0.17 11.6 0.1 0.22 11.2 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-C2H2_2 PF12756.7 KXS13719.1 - 0.18 12.1 0.1 0.26 11.7 0.1 1.2 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Spherulin4 PF12138.8 KXS13720.1 - 1.2e-47 162.6 0.0 1.5e-47 162.3 0.0 1.1 1 0 0 1 1 1 1 Spherulation-specific family 4 DUF1524 PF07510.11 KXS13722.1 - 3.9e-09 36.5 0.0 4.7e-09 36.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1524) RRM_1 PF00076.22 KXS13726.1 - 5.2e-35 119.1 0.0 5.7e-18 64.5 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KXS13726.1 - 0.00048 20.1 0.0 0.21 11.6 0.0 2.2 2 0 0 2 2 2 2 RNA binding motif ATP-grasp_2 PF08442.10 KXS13726.1 - 0.00086 18.9 2.2 0.21 11.1 0.0 2.6 2 1 1 3 3 3 2 ATP-grasp domain Limkain-b1 PF11608.8 KXS13726.1 - 0.0078 16.3 0.0 0.57 10.3 0.0 2.4 2 0 0 2 2 2 1 Limkain b1 GRP PF07172.11 KXS13726.1 - 0.35 11.6 21.5 2.4 8.9 7.2 2.4 2 0 0 2 2 2 0 Glycine rich protein family Mito_carr PF00153.27 KXS13727.1 - 0.12 12.3 0.0 0.14 12.1 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial carrier protein ABC_membrane PF00664.23 KXS13731.1 - 1.9e-60 204.9 3.0 2.4e-60 204.5 3.0 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KXS13731.1 - 1.3e-34 119.7 0.0 2.4e-34 118.8 0.0 1.5 1 0 0 1 1 1 1 ABC transporter Zeta_toxin PF06414.12 KXS13731.1 - 0.00011 21.6 0.0 0.00023 20.5 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin SMC_N PF02463.19 KXS13731.1 - 0.00013 21.5 0.0 0.0028 17.1 0.0 1.8 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 KXS13731.1 - 0.014 14.2 0.0 0.014 14.2 0.0 1.6 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_16 PF13191.6 KXS13731.1 - 0.02 15.3 0.4 0.092 13.1 0.0 2.2 2 1 0 2 2 2 0 AAA ATPase domain RsgA_GTPase PF03193.16 KXS13731.1 - 0.16 11.8 0.1 0.35 10.7 0.1 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 KXS13731.1 - 0.33 10.7 1.5 0.72 9.6 1.5 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Pkinase PF00069.25 KXS13732.1 - 2.9e-10 39.9 0.0 3.4e-10 39.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS13732.1 - 0.00079 18.8 0.0 0.00094 18.5 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXS13732.1 - 0.15 12.0 0.0 0.25 11.3 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family BRCT PF00533.26 KXS13734.1 - 1.8e-21 76.3 0.0 6.6e-09 36.0 0.0 3.7 3 0 0 3 3 3 3 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 KXS13734.1 - 4.5e-21 74.6 0.0 1.6e-13 50.3 0.0 3.6 3 0 0 3 3 3 2 twin BRCT domain BRCT_2 PF16589.5 KXS13734.1 - 5.5e-16 58.7 0.0 0.00061 20.2 0.0 3.8 4 0 0 4 4 4 3 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 KXS13734.1 - 0.0018 18.1 0.0 0.057 13.3 0.0 2.5 2 0 0 2 2 2 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_3 PF18428.1 KXS13734.1 - 0.0033 17.5 0.0 7 6.8 0.0 3.4 3 0 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 KXS13734.1 - 0.024 14.9 0.0 4.2 7.7 0.0 3.6 4 0 0 4 4 4 0 DNA ligase 3 BRCT domain Axin_b-cat_bind PF08833.10 KXS13734.1 - 0.055 13.6 1.4 16 5.7 0.1 3.2 2 0 0 2 2 2 0 Axin beta-catenin binding domain DUF3363 PF11843.8 KXS13734.1 - 0.097 11.6 0.1 3.5 6.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3363) Rad60-SLD PF11976.8 KXS13735.1 - 0.00014 21.6 0.0 0.0064 16.3 0.0 2.3 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Takusan PF04822.13 KXS13735.1 - 0.048 13.5 0.0 0.094 12.6 0.0 1.4 1 0 0 1 1 1 0 Takusan DeoC PF01791.9 KXS13736.1 - 3.1e-10 40.1 3.1 1.1e-09 38.2 3.1 1.7 1 1 0 1 1 1 1 DeoC/LacD family aldolase DLH PF01738.18 KXS13737.1 - 3.7e-25 88.8 0.0 6.2e-25 88.0 0.0 1.3 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 KXS13737.1 - 1.1e-05 25.3 0.0 1.4e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.18 KXS13738.1 - 5.3e-17 62.1 0.0 1.3e-16 60.8 0.0 1.6 1 1 0 1 1 1 1 Dienelactone hydrolase family DLH PF01738.18 KXS13739.1 - 7.7e-24 84.4 0.0 1.5e-23 83.5 0.0 1.4 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 KXS13739.1 - 0.00017 21.3 0.0 0.00023 20.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF4232 PF14016.6 KXS13741.1 - 0.049 13.8 0.4 0.083 13.0 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4232) zf-RING_2 PF13639.6 KXS13742.1 - 1.8e-12 47.4 3.9 2.7e-12 46.8 3.9 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KXS13742.1 - 3.4e-09 36.3 1.2 7.2e-09 35.2 1.2 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 KXS13742.1 - 1.4e-08 34.6 1.5 1.6e-07 31.2 2.4 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KXS13742.1 - 2.9e-08 33.5 1.1 4.4e-08 32.9 1.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXS13742.1 - 5.7e-08 32.5 3.2 9.1e-08 31.8 3.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KXS13742.1 - 4.2e-07 30.1 4.8 9.4e-07 29.0 4.8 1.5 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KXS13742.1 - 8.2e-07 28.9 0.6 1.2e-06 28.3 0.6 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KXS13742.1 - 4.7e-05 23.2 1.1 6.8e-05 22.6 1.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KXS13742.1 - 0.0002 21.3 0.8 0.00038 20.4 0.8 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 KXS13742.1 - 0.00025 20.6 2.2 0.00041 19.9 2.2 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 KXS13742.1 - 0.0017 18.5 3.2 0.0031 17.6 3.2 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KXS13742.1 - 0.0057 16.5 2.8 0.011 15.6 2.8 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 KXS13742.1 - 0.02 14.7 1.6 0.031 14.1 1.6 1.2 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_1 PF14446.6 KXS13742.1 - 0.038 13.9 1.6 0.44 10.5 0.4 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 FANCL_C PF11793.8 KXS13742.1 - 0.08 13.1 3.2 0.48 10.7 3.2 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain DUF4381 PF14316.6 KXS13742.1 - 0.081 13.2 1.5 0.11 12.7 0.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) PHD PF00628.29 KXS13742.1 - 0.12 12.3 1.6 0.27 11.2 1.6 1.6 1 1 0 1 1 1 0 PHD-finger zf-C3H2C3 PF17122.5 KXS13742.1 - 0.16 12.0 3.2 0.41 10.7 3.2 1.8 1 0 0 1 1 1 0 Zinc-finger RINGv PF12906.7 KXS13742.1 - 1.6 9.0 3.5 2.9 8.1 3.5 1.5 1 0 0 1 1 1 0 RING-variant domain Lactamase_B PF00753.27 KXS13744.1 - 1.1e-20 74.4 1.1 1.8e-20 73.8 1.1 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KXS13744.1 - 0.0081 15.7 0.2 0.02 14.4 0.2 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain F-box-like PF12937.7 KXS13746.1 - 0.00028 20.7 0.0 0.00061 19.6 0.0 1.6 1 0 0 1 1 1 1 F-box-like Acetyltransf_3 PF13302.7 KXS13747.1 - 2.7e-22 79.9 0.0 2.6e-21 76.8 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXS13747.1 - 0.0019 18.4 0.0 0.0027 17.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 KXS13747.1 - 0.0087 15.7 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DIOX_N PF14226.6 KXS13748.1 - 3.2e-23 82.7 0.0 5.1e-23 82.1 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KXS13748.1 - 1.1e-22 80.4 0.0 2.9e-22 79.1 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Pkinase PF00069.25 KXS13749.1 - 5e-44 150.6 0.0 5.2e-34 117.8 0.0 2.8 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXS13749.1 - 5e-21 75.1 0.0 8e-18 64.6 0.0 3.1 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KXS13749.1 - 1.2e-07 31.3 0.0 7.8e-05 22.1 0.0 2.2 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 KXS13749.1 - 1e-06 28.2 0.0 1.8e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXS13749.1 - 7.7e-05 22.7 0.0 0.00073 19.5 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 KXS13749.1 - 0.00018 21.2 0.0 0.00032 20.4 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 KXS13749.1 - 0.0012 17.9 0.0 0.0022 17.0 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 KXS13749.1 - 0.028 13.2 0.0 0.96 8.1 0.0 2.2 2 0 0 2 2 2 0 Fungal protein kinase Choline_kinase PF01633.20 KXS13749.1 - 0.046 13.3 0.1 1.6 8.3 0.0 2.1 1 1 1 2 2 2 0 Choline/ethanolamine kinase Ank_3 PF13606.6 KXS13752.1 - 3.3e-06 27.0 0.4 0.25 12.0 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 KXS13752.1 - 5.6e-06 26.6 1.4 1.8 9.1 0.2 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.7 KXS13752.1 - 1.6e-05 25.4 0.2 0.0087 16.6 0.0 3.1 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Tropomyosin PF00261.20 KXS13752.1 - 0.00048 19.6 0.4 0.00069 19.1 0.4 1.1 1 0 0 1 1 1 1 Tropomyosin Ank_5 PF13857.6 KXS13752.1 - 0.014 15.7 0.1 7.3 7.0 0.0 2.9 3 0 0 3 3 3 0 Ankyrin repeats (many copies) TrwC PF08751.11 KXS13752.1 - 0.014 15.0 0.4 0.75 9.3 0.0 2.1 2 0 0 2 2 2 0 TrwC relaxase GST_C PF00043.25 KXS13755.1 - 8.3e-09 35.6 0.0 1.5e-08 34.8 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KXS13755.1 - 1e-08 35.5 0.0 2.4e-08 34.3 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KXS13755.1 - 1.9e-07 31.0 0.1 6.3e-07 29.3 0.1 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KXS13755.1 - 7.4e-07 29.4 0.0 2.1e-06 27.9 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KXS13755.1 - 0.0028 17.8 0.0 0.0078 16.4 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KXS13755.1 - 0.017 15.4 0.1 0.052 13.9 0.1 1.8 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 KXS13755.1 - 0.024 14.4 0.0 0.041 13.7 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain LSM PF01423.22 KXS13756.1 - 2.3e-16 59.3 0.1 2.7e-16 59.0 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KXS13756.1 - 0.00019 21.5 0.1 0.00022 21.3 0.1 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain DUF1461 PF07314.11 KXS13756.1 - 0.043 13.7 0.0 0.043 13.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1461) FLgD_tudor PF13861.6 KXS13756.1 - 0.065 13.5 0.4 0.097 12.9 0.1 1.3 2 0 0 2 2 2 0 FlgD Tudor-like domain SH3_2 PF07653.17 KXS13757.1 - 0.11 12.2 0.0 17 5.2 0.0 2.5 2 0 0 2 2 2 0 Variant SH3 domain EPL1 PF10513.9 KXS13758.1 - 2.7e-17 63.6 0.0 4.5e-17 62.9 0.0 1.3 1 0 0 1 1 1 1 Enhancer of polycomb-like p450 PF00067.22 KXS13759.1 - 6.8e-66 222.9 0.0 8.8e-66 222.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.7 KXS13760.1 - 0.00067 19.5 0.2 0.002 18.0 0.2 1.9 1 0 0 1 1 1 1 F-box-like Tim54 PF11711.8 KXS13761.1 - 8.9e-35 120.2 0.1 1.6e-33 116.0 0.1 2.4 1 1 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 PEMT PF04191.13 KXS13762.1 - 6.4e-47 158.3 19.3 4.4e-30 104.2 1.6 3.5 4 0 0 4 4 4 2 Phospholipid methyltransferase HECW_N PF16562.5 KXS13762.1 - 0.12 12.2 0.0 0.3 10.9 0.0 1.6 1 0 0 1 1 1 0 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 Aldedh PF00171.22 KXS13763.1 - 2.7e-183 609.7 0.3 3.1e-183 609.5 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KXS13763.1 - 0.00013 21.1 0.0 0.0002 20.5 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) NAD_binding_10 PF13460.6 KXS13766.1 - 6.8e-12 45.7 0.0 1.2e-11 44.8 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KXS13766.1 - 5.3e-07 29.4 0.0 7.2e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 KXS13766.1 - 2.6e-06 27.1 0.0 8.1e-06 25.5 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 KXS13766.1 - 0.0057 16.1 0.0 0.01 15.3 0.0 1.3 1 1 0 1 1 1 1 short chain dehydrogenase 3Beta_HSD PF01073.19 KXS13766.1 - 0.0071 15.4 0.0 0.0085 15.1 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DUF3708 PF12501.8 KXS13766.1 - 0.019 14.8 0.0 0.022 14.6 0.0 1.3 1 1 0 1 1 1 0 Phosphate ATP-binding cassette transporter F420_oxidored PF03807.17 KXS13766.1 - 0.023 15.2 0.0 0.04 14.5 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DUF4134 PF13572.6 KXS13766.1 - 0.06 13.6 0.3 0.12 12.7 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4134) GDP_Man_Dehyd PF16363.5 KXS13766.1 - 0.23 10.8 0.0 0.34 10.3 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase UQ_con PF00179.26 KXS13767.1 - 3e-49 166.3 0.0 3.4e-49 166.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RNase_PH PF01138.21 KXS13770.1 - 5.4e-23 81.9 0.2 9e-23 81.2 0.2 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 GHMP_kinases_C PF08544.13 KXS13770.1 - 0.085 13.2 0.3 0.16 12.4 0.3 1.5 1 0 0 1 1 1 0 GHMP kinases C terminal Ank_2 PF12796.7 KXS13771.1 - 1.8e-24 86.1 0.4 2.1e-10 41.0 0.2 2.8 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXS13771.1 - 7.2e-20 71.1 10.6 1.6e-05 25.3 0.5 4.9 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXS13771.1 - 1.5e-17 63.4 1.2 3.5e-05 24.0 0.3 4.4 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXS13771.1 - 2.4e-14 52.0 1.3 0.00016 21.8 0.1 5.5 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.30 KXS13771.1 - 1.2e-13 50.9 4.7 5.6e-05 23.4 0.3 6.0 5 1 0 5 5 5 3 Ankyrin repeat WD40 PF00400.32 KXS13772.1 - 2e-28 98.1 5.9 2.4e-05 25.0 0.0 6.2 7 0 0 7 7 7 5 WD domain, G-beta repeat Sof1 PF04158.14 KXS13772.1 - 8.2e-24 83.7 5.9 1.5e-23 82.9 5.9 1.4 1 0 0 1 1 1 1 Sof1-like domain ANAPC4_WD40 PF12894.7 KXS13772.1 - 2.8e-08 34.0 0.3 0.0027 17.9 0.0 4.0 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KXS13772.1 - 0.00065 18.7 0.0 0.011 14.7 0.0 2.3 2 1 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KXS13772.1 - 0.0044 16.9 0.1 0.11 12.3 0.0 2.0 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Pex14_N PF04695.13 KXS13773.1 - 5.6e-33 114.8 6.8 5.6e-33 114.8 6.8 3.1 2 1 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1664 PF07889.12 KXS13773.1 - 0.00022 21.3 2.5 0.0004 20.4 2.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1664) Rx_N PF18052.1 KXS13773.1 - 0.00029 21.0 5.1 0.17 12.2 1.4 2.5 1 1 1 2 2 2 2 Rx N-terminal domain DUF3584 PF12128.8 KXS13773.1 - 0.002 15.8 2.5 0.0028 15.3 2.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Baculo_PEP_C PF04513.12 KXS13773.1 - 0.0022 18.1 5.6 0.0034 17.4 5.6 1.2 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus EzrA PF06160.12 KXS13773.1 - 0.0026 16.0 5.4 0.0036 15.5 5.4 1.2 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA Golgin_A5 PF09787.9 KXS13773.1 - 0.003 17.1 3.0 0.005 16.3 3.0 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 5 YkyA PF10368.9 KXS13773.1 - 0.012 15.2 7.5 0.024 14.3 7.5 1.4 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein DUF4763 PF15960.5 KXS13773.1 - 0.019 14.3 0.9 0.031 13.6 0.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4763) TolA_bind_tri PF16331.5 KXS13773.1 - 0.023 14.8 2.3 0.12 12.5 0.2 2.5 2 1 1 3 3 2 0 TolA binding protein trimerisation RPW8 PF05659.11 KXS13773.1 - 0.029 14.1 3.1 0.055 13.1 3.1 1.5 1 1 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 XhlA PF10779.9 KXS13773.1 - 0.033 14.4 3.0 0.033 14.4 3.0 2.8 3 0 0 3 3 2 0 Haemolysin XhlA Hormone_1 PF00103.20 KXS13773.1 - 0.036 13.8 2.5 0.055 13.2 2.5 1.2 1 0 0 1 1 1 0 Somatotropin hormone family UPF0242 PF06785.11 KXS13773.1 - 0.04 14.0 0.2 0.077 13.1 0.2 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Cluap1 PF10234.9 KXS13773.1 - 0.046 13.1 3.6 0.068 12.6 3.6 1.3 1 0 0 1 1 1 0 Clusterin-associated protein-1 Spc7 PF08317.11 KXS13773.1 - 0.046 12.6 7.2 0.085 11.7 7.2 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein Laminin_II PF06009.12 KXS13773.1 - 0.053 13.5 10.3 0.095 12.7 10.3 1.4 1 0 0 1 1 1 0 Laminin Domain II TMPIT PF07851.13 KXS13773.1 - 0.056 12.7 4.4 0.086 12.1 4.4 1.2 1 0 0 1 1 1 0 TMPIT-like protein NPV_P10 PF05531.12 KXS13773.1 - 0.063 13.7 12.1 0.68 10.4 6.4 2.8 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF848 PF05852.11 KXS13773.1 - 0.11 12.6 5.9 0.21 11.7 5.9 1.4 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) Fusion_gly PF00523.18 KXS13773.1 - 0.13 10.5 3.3 0.15 10.3 1.2 1.8 1 1 1 2 2 2 0 Fusion glycoprotein F0 LMBR1 PF04791.16 KXS13773.1 - 0.24 10.3 0.1 0.33 9.8 0.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4208 PF13907.6 KXS13773.1 - 0.25 11.8 1.1 0.47 10.9 1.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4208) COG2 PF06148.11 KXS13773.1 - 0.32 11.1 5.7 0.29 11.2 3.0 2.0 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 YabA PF06156.13 KXS13773.1 - 0.38 11.4 2.0 0.94 10.2 2.0 1.7 1 0 0 1 1 1 0 Initiation control protein YabA PRAS PF15798.5 KXS13773.1 - 0.4 11.3 3.4 0.22 12.1 0.6 2.0 2 0 0 2 2 1 0 Proline-rich AKT1 substrate 1 SKA2 PF16740.5 KXS13773.1 - 0.55 10.0 7.0 3.6 7.4 0.2 2.3 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 Atg14 PF10186.9 KXS13773.1 - 0.63 9.1 3.7 1.1 8.3 3.7 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TMF_TATA_bd PF12325.8 KXS13773.1 - 0.66 10.2 8.3 0.79 10.0 5.8 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding CCDC-167 PF15188.6 KXS13773.1 - 0.75 10.2 4.9 2.2 8.7 4.9 1.8 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 Fib_alpha PF08702.10 KXS13773.1 - 0.78 9.9 8.1 1.4 9.1 8.1 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Baculo_p24 PF05073.12 KXS13773.1 - 0.93 9.2 4.1 1.5 8.6 4.1 1.2 1 0 0 1 1 1 0 Baculovirus P24 capsid protein SKA1 PF07160.12 KXS13773.1 - 0.99 9.2 7.2 2.1 8.1 7.2 1.7 1 1 0 1 1 1 0 Spindle and kinetochore-associated protein 1 DUF1216 PF06746.11 KXS13773.1 - 1.2 9.1 9.2 0.34 10.9 5.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1216) V_ATPase_I PF01496.19 KXS13773.1 - 1.3 6.8 2.6 1.9 6.3 2.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Muted PF14942.6 KXS13773.1 - 1.4 9.2 6.6 9.5 6.6 6.5 2.1 1 1 0 1 1 1 0 Organelle biogenesis, Muted-like protein DUF948 PF06103.11 KXS13773.1 - 5.2 7.4 10.9 1.7 8.9 4.6 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Uso1_p115_C PF04871.13 KXS13773.1 - 6.7 7.1 14.8 0.64 10.4 8.4 2.3 2 1 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Noc2 PF03715.13 KXS13774.1 - 1.8e-74 250.7 0.0 2.4e-74 250.3 0.0 1.1 1 0 0 1 1 1 1 Noc2p family BrkDBD PF09607.10 KXS13775.1 - 0.19 11.5 0.0 1.8 8.4 0.0 2.1 2 0 0 2 2 2 0 Brinker DNA-binding domain Inhibitor_I36 PF03995.13 KXS13775.1 - 0.72 9.8 12.6 1.2 9.1 2.3 2.6 1 1 2 3 3 3 0 Peptidase inhibitor family I36 BCD PF15461.6 KXS13776.1 - 0.11 12.0 0.1 0.12 11.8 0.1 1.1 1 0 0 1 1 1 0 Beta-carotene 15,15'-dioxygenase WD40 PF00400.32 KXS13779.1 - 2.3e-10 40.9 14.6 0.00028 21.6 0.2 5.8 5 1 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXS13779.1 - 1.1e-06 28.8 0.5 0.00082 19.6 0.1 3.8 2 2 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KXS13779.1 - 0.0033 17.3 0.7 0.035 14.0 0.1 2.4 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.22 KXS13780.1 - 4.1e-25 87.4 0.2 2.3e-13 49.8 0.0 2.6 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KXS13780.1 - 5.3e-10 39.0 0.0 9e-05 22.1 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KXS13780.1 - 4.1e-05 23.3 0.0 0.002 17.9 0.0 2.2 2 0 0 2 2 2 1 Occluded RNA-recognition motif DUF4775 PF16001.5 KXS13780.1 - 0.03 13.8 8.7 0.041 13.3 8.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4775) Limkain-b1 PF11608.8 KXS13780.1 - 0.041 14.0 0.0 0.25 11.5 0.0 2.1 2 0 0 2 2 2 0 Limkain b1 PHM7_cyt PF14703.6 KXS13780.1 - 0.092 13.0 2.3 8.1 6.6 0.8 3.4 2 2 1 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter DUF846 PF05832.12 KXS13782.1 - 1.1e-52 177.8 13.0 1.3e-52 177.5 13.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) DDDD PF10161.9 KXS13782.1 - 5.1 6.9 7.5 13 5.6 0.1 3.1 3 0 0 3 3 3 0 Putative mitochondrial precursor protein Iso_dh PF00180.20 KXS13783.1 - 3.8e-75 253.2 0.0 4.5e-75 253.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase MlaC PF05494.12 KXS13783.1 - 0.032 14.0 0.0 6.9 6.4 0.0 3.1 2 1 1 3 3 3 0 MlaC protein Rbx_binding PF18113.1 KXS13783.1 - 0.091 12.6 0.0 0.32 10.8 0.0 1.9 2 0 0 2 2 2 0 Rubredoxin binding C-terminal domain DHFR_2 PF06442.11 KXS13783.1 - 0.097 12.5 0.0 9.3 6.2 0.0 2.6 2 0 0 2 2 2 0 R67 dihydrofolate reductase S-AdoMet_synt_C PF02773.16 KXS13784.1 - 9.4e-60 200.6 0.4 4.8e-59 198.3 0.0 2.1 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 KXS13784.1 - 3.4e-47 159.6 0.0 6.9e-47 158.6 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 KXS13784.1 - 2.3e-45 153.3 0.3 6e-45 152.0 0.3 1.7 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain AdoMet_Synthase PF01941.19 KXS13784.1 - 0.0075 15.1 1.1 0.11 11.3 0.2 2.1 1 1 1 2 2 2 1 S-adenosylmethionine synthetase (AdoMet synthetase) WD40 PF00400.32 KXS13787.1 - 6.9e-41 137.5 17.4 8.7e-08 32.7 0.4 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.8 KXS13787.1 - 0.00046 19.0 1.4 0.24 10.0 0.1 3.3 1 1 2 3 3 3 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 KXS13787.1 - 0.0051 17.1 2.1 1.4 9.3 0.1 4.1 1 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 KXS13787.1 - 0.085 11.6 0.2 36 2.9 0.0 3.9 2 1 3 5 5 5 0 Nup133 N terminal like WD40_like PF17005.5 KXS13787.1 - 0.1 11.9 0.0 0.46 9.8 0.0 2.0 1 1 0 2 2 2 0 WD40-like domain GCV_T PF01571.21 KXS13788.1 - 1.8e-08 34.1 0.0 2.7e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain Xpo1 PF08389.12 KXS13789.1 - 5.7e-28 97.9 0.0 1.3e-27 96.7 0.0 1.6 1 0 0 1 1 1 1 Exportin 1-like protein Sema PF01403.19 KXS13790.1 - 0.16 10.8 0.1 0.22 10.3 0.1 1.1 1 0 0 1 1 1 0 Sema domain Spt20 PF12090.8 KXS13790.1 - 6 6.4 14.0 11 5.6 14.0 1.3 1 0 0 1 1 1 0 Spt20 family Cep57_CLD PF14073.6 KXS13791.1 - 0.00014 22.0 12.3 0.00014 22.0 12.3 2.2 2 0 0 2 2 2 1 Centrosome localisation domain of Cep57 GAS PF13851.6 KXS13791.1 - 0.029 13.7 17.3 0.035 13.5 13.2 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF1415 PF07209.12 KXS13791.1 - 0.047 13.4 0.1 0.082 12.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1415) Tropomyosin_1 PF12718.7 KXS13791.1 - 1 9.5 18.2 0.48 10.6 13.2 2.1 2 0 0 2 2 2 0 Tropomyosin like DUF3782 PF12644.7 KXS13791.1 - 3.2 8.0 7.8 0.59 10.3 0.2 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3782) V_ATPase_I PF01496.19 KXS13791.1 - 3.2 5.5 5.9 1.5 6.6 2.8 1.7 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family PspB PF06667.12 KXS13791.1 - 3.5 7.8 10.5 20 5.3 0.1 3.5 2 1 1 3 3 3 0 Phage shock protein B DUF724 PF05266.14 KXS13791.1 - 5.8 6.7 10.0 3.7 7.3 6.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF724) CorA PF01544.18 KXS13791.1 - 9.7 5.4 8.3 2.9 7.1 5.5 1.5 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein WD40 PF00400.32 KXS13792.1 - 9.6e-14 51.6 6.3 0.0001 23.0 0.0 8.0 9 0 0 9 9 9 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXS13792.1 - 0.003 17.8 0.0 4.2 7.7 0.0 4.3 4 1 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleotid_trans PF03407.16 KXS13792.1 - 0.027 14.4 0.0 0.047 13.7 0.0 1.3 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase Nup160 PF11715.8 KXS13792.1 - 0.12 11.0 0.5 5 5.7 0.1 2.2 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Cation_ATPase_C PF00689.21 KXS13793.1 - 1.8e-21 76.7 8.9 3.5e-21 75.7 8.9 1.5 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 KXS13793.1 - 9e-10 38.5 0.0 1.9e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KXS13793.1 - 5.4e-09 36.6 0.8 4.1e-07 30.5 0.7 3.1 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KXS13793.1 - 0.00044 19.8 1.0 0.00044 19.8 1.0 3.2 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KXS13793.1 - 0.00084 19.1 0.5 0.018 14.8 0.3 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF4197 PF13852.6 KXS13793.1 - 0.17 11.6 0.0 0.32 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4197) DHC_N1 PF08385.12 KXS13794.1 - 2e-179 597.9 8.9 2e-179 597.9 8.9 3.3 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.7 KXS13794.1 - 1.7e-147 490.7 0.0 1.2e-145 484.6 0.0 2.8 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 KXS13794.1 - 2.2e-125 418.9 3.1 2.2e-125 418.9 3.1 4.5 6 1 0 6 6 5 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 KXS13794.1 - 6.6e-95 317.3 0.0 1.4e-94 316.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 KXS13794.1 - 1.1e-93 313.8 1.6 1.9e-92 309.7 0.0 3.5 3 0 0 3 3 3 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 KXS13794.1 - 5.9e-87 290.4 4.0 2.4e-86 288.4 4.0 2.2 1 0 0 1 1 1 1 ATP-binding dynein motor region AAA_7 PF12775.7 KXS13794.1 - 7.8e-67 224.3 0.4 4.3e-61 205.6 0.0 4.0 4 0 0 4 4 3 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 KXS13794.1 - 2.6e-56 189.9 0.0 8.6e-56 188.3 0.0 2.0 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 KXS13794.1 - 2.2e-43 147.1 0.1 2.7e-39 133.9 0.0 4.5 5 0 0 5 5 3 2 Dynein heavy chain region D6 P-loop domain MT PF12777.7 KXS13794.1 - 1.6e-38 132.6 11.5 4.4e-38 131.2 11.5 1.8 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.14 KXS13794.1 - 2.8e-23 82.5 0.0 8.6e-09 35.5 0.0 5.3 4 0 0 4 4 4 4 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 KXS13794.1 - 2.6e-18 66.1 0.1 3.7e-17 62.4 0.0 3.0 3 0 0 3 3 2 1 AAA+ lid domain Dynein_AAA_lid PF17852.1 KXS13794.1 - 8.4e-18 64.7 0.1 1.5e-16 60.7 0.0 3.1 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_16 PF13191.6 KXS13794.1 - 3.6e-09 37.2 0.3 0.11 12.8 0.0 6.0 5 0 0 5 5 5 2 AAA ATPase domain AAA PF00004.29 KXS13794.1 - 1.2e-08 35.4 3.0 0.75 10.2 0.0 5.4 5 0 0 5 5 4 3 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KXS13794.1 - 9.9e-07 29.1 1.6 0.98 9.7 0.0 4.9 4 0 0 4 4 4 2 AAA domain AAA_18 PF13238.6 KXS13794.1 - 0.00056 20.5 0.1 0.48 11.0 0.0 3.8 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.6 KXS13794.1 - 0.0052 16.9 0.1 0.25 11.5 0.0 3.4 3 0 0 3 3 2 1 AAA domain RNA_helicase PF00910.22 KXS13794.1 - 0.008 16.6 0.1 2.3 8.6 0.0 3.9 3 0 0 3 3 3 1 RNA helicase AAA_19 PF13245.6 KXS13794.1 - 0.012 15.9 9.6 0.21 11.9 0.1 4.9 4 0 0 4 4 4 0 AAA domain Mg_chelatase PF01078.21 KXS13794.1 - 0.055 12.8 0.4 5.9 6.2 0.0 2.9 3 0 0 3 3 2 0 Magnesium chelatase, subunit ChlI ATPase PF06745.13 KXS13794.1 - 0.077 12.3 1.3 0.27 10.6 0.0 2.6 2 0 0 2 2 2 0 KaiC AAA_11 PF13086.6 KXS13794.1 - 0.14 11.9 12.8 1.5 8.6 0.0 4.8 5 0 0 5 5 5 0 AAA domain AAA_24 PF13479.6 KXS13794.1 - 0.16 11.7 5.6 22 4.7 0.0 5.2 4 1 1 5 5 5 0 AAA domain Cut12 PF11500.8 KXS13794.1 - 0.21 11.5 3.2 4.6 7.2 0.3 3.0 2 0 0 2 2 2 0 Spindle pole body formation-associated protein DUF4515 PF14988.6 KXS13795.1 - 9.4e-12 45.2 29.2 9.4e-12 45.2 29.2 3.1 2 2 0 2 2 2 1 Domain of unknown function (DUF4515) Pox_A_type_inc PF04508.12 KXS13795.1 - 0.004 16.9 3.2 0.026 14.4 0.0 3.4 3 0 0 3 3 3 1 Viral A-type inclusion protein repeat UPF0242 PF06785.11 KXS13795.1 - 0.016 15.3 20.1 0.016 15.3 20.1 3.6 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus BRE PF06113.12 KXS13796.1 - 5.3e-08 32.1 0.0 1.8e-07 30.4 0.0 1.8 1 1 0 1 1 1 1 Brain and reproductive organ-expressed protein (BRE) Ank_2 PF12796.7 KXS13797.1 - 2.9e-17 63.0 0.1 1.2e-07 32.2 0.1 3.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXS13797.1 - 1e-11 45.1 0.5 8.9e-06 26.2 0.0 3.6 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXS13797.1 - 4.5e-09 36.4 2.4 0.0055 17.0 0.2 4.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXS13797.1 - 1.1e-08 34.7 1.8 0.084 13.5 0.0 5.0 4 1 1 5 5 5 2 Ankyrin repeat Ank PF00023.30 KXS13797.1 - 4.1e-06 27.0 5.4 0.19 12.2 0.0 4.6 4 1 0 4 4 4 2 Ankyrin repeat SPG48 PF14764.6 KXS13797.1 - 0.077 13.5 0.0 0.15 12.5 0.0 1.6 1 0 0 1 1 1 0 AP-5 complex subunit, vesicle trafficking Atg14 PF10186.9 KXS13798.1 - 1e-13 51.1 0.1 3.2e-13 49.5 0.1 1.7 1 1 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 APG6 PF04111.12 KXS13798.1 - 1.7e-05 24.9 0.0 2.8e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Apg6 BARA domain DUF3799 PF12684.7 KXS13798.1 - 0.062 13.1 0.0 0.092 12.5 0.0 1.1 1 0 0 1 1 1 0 PDDEXK-like domain of unknown function (DUF3799) Kre28 PF17097.5 KXS13798.1 - 0.11 11.5 0.4 0.18 10.7 0.4 1.3 1 0 0 1 1 1 0 Spindle pole body component DNA_pol_delta_4 PF04081.13 KXS13799.1 - 1.4e-23 83.6 0.5 1.7e-23 83.4 0.5 1.1 1 0 0 1 1 1 1 DNA polymerase delta, subunit 4 Dimer_Tnp_hAT PF05699.14 KXS13801.1 - 1.3e-16 60.2 0.0 6.2e-16 58.0 0.0 1.9 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region DUF4175 PF13779.6 KXS13801.1 - 0.14 10.0 1.0 0.18 9.7 1.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF3334 PF11813.8 KXS13802.1 - 0.076 12.7 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3334) ORC4_C PF14629.6 KXS13802.1 - 0.13 11.6 0.0 0.16 11.4 0.0 1.1 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 4 C-terminus Ferric_reduct PF01794.19 KXS13803.1 - 3.6e-14 53.0 11.6 6.1e-14 52.2 11.6 1.4 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KXS13803.1 - 4.5e-09 36.4 0.1 1e-08 35.2 0.1 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 KXS13803.1 - 6.3e-06 26.4 0.0 0.031 14.4 0.0 2.3 1 1 1 2 2 2 2 Ferric reductase NAD binding domain DUF5461 PF17545.2 KXS13803.1 - 0.13 12.6 0.2 1.1 9.6 0.3 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5461) eIF-3_zeta PF05091.12 KXS13805.1 - 3.8e-139 465.0 0.0 5.1e-138 461.3 0.0 2.3 1 1 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Putative_PNPOx PF01243.20 KXS13806.1 - 3.1e-08 33.7 0.0 4.8e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase EF-hand_1 PF00036.32 KXS13809.1 - 4.9e-37 122.7 16.8 1.8e-09 36.5 0.4 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KXS13809.1 - 4.2e-32 110.4 8.7 1.2e-16 60.9 0.3 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KXS13809.1 - 2.7e-28 95.4 8.9 9.1e-09 34.6 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 KXS13809.1 - 1.2e-26 92.3 13.7 2.4e-12 46.5 0.9 3.8 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 KXS13809.1 - 2.5e-18 64.7 14.4 3.2e-05 23.2 0.3 4.4 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 KXS13809.1 - 1.6e-14 53.9 0.1 4.9e-06 26.8 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 KXS13809.1 - 4.6e-06 26.5 4.5 0.16 11.9 0.4 3.2 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 KXS13809.1 - 0.00011 22.4 0.8 0.43 10.9 0.2 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region SurA_N_3 PF13624.6 KXS13809.1 - 0.00011 22.0 1.0 0.4 10.5 0.1 2.1 1 1 0 2 2 2 2 SurA N-terminal domain EF-hand_14 PF17959.1 KXS13809.1 - 0.0012 19.2 1.2 1.2 9.6 0.1 2.4 1 1 1 2 2 2 2 EF-hand domain HTH_40 PF14493.6 KXS13809.1 - 0.0052 17.2 2.9 0.58 10.6 1.3 2.5 1 1 2 3 3 3 1 Helix-turn-helix domain Sigma54_CBD PF04963.13 KXS13809.1 - 0.0066 16.3 0.2 0.0087 15.9 0.2 1.2 1 0 0 1 1 1 1 Sigma-54 factor, core binding domain Dockerin_1 PF00404.18 KXS13809.1 - 0.013 15.7 0.1 0.89 9.8 0.1 2.5 2 1 0 2 2 2 0 Dockerin type I domain SurA_N_2 PF13623.6 KXS13809.1 - 0.013 15.3 0.6 1.2 9.0 0.2 2.3 1 1 1 2 2 2 0 SurA N-terminal domain TerB PF05099.13 KXS13809.1 - 0.014 15.4 2.0 0.25 11.3 0.0 2.8 1 1 1 3 3 3 0 Tellurite resistance protein TerB EF-hand_11 PF08976.11 KXS13809.1 - 0.037 14.9 0.3 2.9 8.8 0.0 2.1 1 1 1 2 2 2 0 EF-hand domain FlgD PF03963.14 KXS13809.1 - 0.056 13.8 0.0 0.19 12.1 0.0 1.8 2 0 0 2 2 2 0 Flagellar hook capping protein - N-terminal region Caleosin PF05042.13 KXS13809.1 - 0.077 12.9 1.5 9.2 6.2 0.0 3.3 1 1 3 4 4 4 0 Caleosin related protein DUF21 PF01595.20 KXS13809.1 - 0.091 12.5 0.6 0.54 9.9 0.2 2.0 2 0 0 2 2 2 0 Cyclin M transmembrane N-terminal domain Toprim_2 PF13155.6 KXS13809.1 - 0.096 13.1 1.1 3.2 8.2 0.2 2.3 1 1 0 2 2 2 0 Toprim-like UPF0154 PF03672.13 KXS13809.1 - 0.11 12.6 0.1 12 6.0 0.0 2.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) Leucyl-specific PF14795.6 KXS13809.1 - 0.11 12.6 0.8 12 6.1 0.0 2.4 2 0 0 2 2 2 0 Leucine-tRNA synthetase-specific domain DUF3911 PF13050.6 KXS13809.1 - 0.13 12.4 2.4 2.7 8.2 0.1 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3911) LETM1 PF07766.13 KXS13809.1 - 0.14 11.5 1.5 0.21 10.9 1.3 1.7 1 1 0 1 1 1 0 LETM1-like protein DUF3349 PF11829.8 KXS13809.1 - 0.15 12.9 1.2 22 5.9 0.1 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF3349) SUB1_ProdP9 PF18213.1 KXS13809.1 - 0.31 10.9 2.2 0.19 11.6 0.3 1.6 2 0 0 2 2 2 0 SUB1 protease Prodomain ProdP9 MgtE_N PF03448.17 KXS13809.1 - 0.58 10.8 4.6 0.18 12.4 0.9 2.0 3 0 0 3 3 2 0 MgtE intracellular N domain Gp-FAR-1 PF05823.12 KXS13809.1 - 0.88 9.9 4.9 0.74 10.2 0.3 2.7 3 1 0 3 3 3 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) EF-hand_10 PF14788.6 KXS13809.1 - 1.5 8.8 5.3 1.8 8.5 0.9 2.6 2 1 1 3 3 3 0 EF hand Rad60-SLD_2 PF13881.6 KXS13810.1 - 2.4e-17 63.0 0.0 3.2e-17 62.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KXS13810.1 - 1.2e-05 25.0 0.0 3e-05 23.7 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin family NARP1 PF12569.8 KXS13811.1 - 2e-177 591.2 14.9 2e-177 591.2 14.9 2.3 2 1 0 2 2 2 1 NMDA receptor-regulated protein 1 TPR_2 PF07719.17 KXS13811.1 - 4.6e-16 57.6 21.5 0.00059 19.8 0.4 9.2 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_16 PF13432.6 KXS13811.1 - 4.4e-12 46.5 13.4 0.057 14.1 0.1 8.5 8 1 1 9 9 8 3 Tetratricopeptide repeat TPR_8 PF13181.6 KXS13811.1 - 9.2e-12 44.2 13.6 0.0014 18.7 0.3 7.8 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.6 KXS13811.1 - 6.4e-11 42.1 14.7 0.65 11.0 0.0 9.2 7 2 4 11 11 9 4 Tetratricopeptide repeat TPR_1 PF00515.28 KXS13811.1 - 8.6e-11 41.2 14.0 0.0097 15.7 0.9 6.6 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_19 PF14559.6 KXS13811.1 - 1.2e-08 35.4 15.2 0.22 12.1 0.0 7.0 6 1 0 6 6 6 3 Tetratricopeptide repeat TPR_9 PF13371.6 KXS13811.1 - 6.9e-07 29.3 2.5 0.29 11.3 0.2 5.9 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.6 KXS13811.1 - 1.4e-05 24.7 8.2 0.045 13.4 0.3 5.4 6 0 0 6 6 6 1 TPR repeat TPR_12 PF13424.6 KXS13811.1 - 3.8e-05 23.9 12.3 0.87 9.9 0.5 6.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_15 PF13429.6 KXS13811.1 - 4.8e-05 22.7 7.8 0.0014 17.9 0.9 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KXS13811.1 - 6.8e-05 22.8 9.3 2 8.5 0.0 6.2 5 2 2 7 7 7 2 Fis1 C-terminal tetratricopeptide repeat ANAPC3 PF12895.7 KXS13811.1 - 0.00063 19.9 11.7 19 5.6 0.1 6.1 5 1 1 6 6 6 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 KXS13811.1 - 0.0012 18.7 7.8 1.8 8.8 0.1 5.6 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 KXS13811.1 - 0.0076 16.8 2.5 27 5.7 0.0 5.5 6 0 0 6 6 5 0 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 KXS13811.1 - 0.018 14.7 0.5 1.4 8.6 0.0 3.2 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_17 PF13431.6 KXS13811.1 - 0.024 15.0 1.4 32 5.2 0.0 5.5 5 1 1 6 6 6 0 Tetratricopeptide repeat ParBc PF02195.18 KXS13815.1 - 0.0041 17.4 0.0 0.0079 16.5 0.0 1.5 1 0 0 1 1 1 1 ParB-like nuclease domain N6_N4_Mtase PF01555.18 KXS13815.1 - 0.013 15.2 0.0 0.027 14.2 0.0 1.5 1 0 0 1 1 1 0 DNA methylase TRAP_beta PF05753.14 KXS13815.1 - 0.092 12.1 0.1 0.77 9.1 0.1 2.1 2 0 0 2 2 2 0 Translocon-associated protein beta (TRAPB) mit_SMPDase PF14724.6 KXS13816.1 - 0.2 9.6 0.0 0.25 9.3 0.0 1.0 1 0 0 1 1 1 0 Mitochondrial-associated sphingomyelin phosphodiesterase Pkinase PF00069.25 KXS13818.1 - 1e-55 189.0 0.0 6.5e-55 186.3 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS13818.1 - 5.4e-23 81.6 0.0 9.6e-16 57.8 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KXS13818.1 - 0.00015 21.7 4.1 0.0034 17.3 1.7 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.20 KXS13818.1 - 0.067 12.8 0.1 0.1 12.1 0.1 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Syntaxin PF00804.25 KXS13819.1 - 1.8e-17 63.7 10.3 3.1e-17 62.9 10.3 1.3 1 0 0 1 1 1 1 Syntaxin SNARE PF05739.19 KXS13819.1 - 1e-06 28.6 1.8 3.8e-06 26.8 1.8 2.0 1 0 0 1 1 1 1 SNARE domain Syntaxin_2 PF14523.6 KXS13819.1 - 0.0012 19.1 10.6 0.0018 18.6 4.2 2.5 2 0 0 2 2 2 1 Syntaxin-like protein XkdW PF09636.10 KXS13819.1 - 0.16 12.1 0.5 0.41 10.8 0.0 1.9 2 0 0 2 2 2 0 XkdW protein 4HB_MCP_1 PF12729.7 KXS13819.1 - 0.36 10.3 10.0 1.4 8.4 0.8 3.0 2 1 1 3 3 3 0 Four helix bundle sensory module for signal transduction Med9 PF07544.13 KXS13819.1 - 0.7 10.0 7.9 0.15 12.2 3.6 2.2 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 V-SNARE PF05008.15 KXS13819.1 - 1.8 9.0 9.5 0.57 10.6 3.7 2.8 2 1 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus H-kinase_dim PF02895.14 KXS13819.1 - 9.3 6.7 10.5 2.9 8.3 1.9 2.9 2 1 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain IPK PF03770.16 KXS13821.1 - 2.1e-42 145.3 0.0 2.5e-42 145.0 0.0 1.1 1 0 0 1 1 1 1 Inositol polyphosphate kinase HgmA PF04209.13 KXS13822.1 - 2.1e-74 250.8 0.1 3.9e-41 141.2 0.0 3.1 1 1 2 3 3 3 3 homogentisate 1,2-dioxygenase WD40 PF00400.32 KXS13823.1 - 3.1e-05 24.7 1.8 0.18 12.8 0.0 4.6 5 0 0 5 5 5 2 WD domain, G-beta repeat Pyr_redox_2 PF07992.14 KXS13824.1 - 2.3e-46 158.4 0.0 3.8e-46 157.7 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXS13824.1 - 3.1e-18 66.1 0.4 2e-13 50.7 0.0 3.8 4 0 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KXS13824.1 - 9e-16 58.1 0.1 5.4e-09 36.3 0.0 2.5 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Glutaredoxin PF00462.24 KXS13824.1 - 8.8e-12 45.1 0.0 2.8e-11 43.5 0.0 1.9 1 1 0 1 1 1 1 Glutaredoxin Pyr_redox_3 PF13738.6 KXS13824.1 - 1.1e-09 38.0 0.0 3.6e-05 23.2 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXS13824.1 - 4e-07 29.5 0.1 1.2e-06 27.9 0.0 1.8 3 0 0 3 3 3 1 FAD binding domain HI0933_like PF03486.14 KXS13824.1 - 3.9e-05 22.5 0.1 0.00029 19.7 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.6 KXS13824.1 - 0.00021 21.5 0.7 0.0085 16.3 0.2 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KXS13824.1 - 0.00072 18.9 0.3 0.0015 17.8 0.3 1.5 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 KXS13824.1 - 0.00081 19.1 1.7 0.0052 16.4 1.5 2.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase HHH_3 PF12836.7 KXS13824.1 - 0.0022 18.2 0.1 4.1 7.7 0.0 3.9 4 0 0 4 4 4 1 Helix-hairpin-helix motif FAD_oxidored PF12831.7 KXS13824.1 - 0.0063 15.9 1.4 0.012 15.0 1.1 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 KXS13824.1 - 0.01 15.2 0.0 0.17 11.1 0.0 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 KXS13824.1 - 0.013 14.6 0.2 0.029 13.5 0.2 1.6 1 0 0 1 1 1 0 Glucose inhibited division protein A K_oxygenase PF13434.6 KXS13824.1 - 0.021 14.0 0.1 0.59 9.2 0.0 2.3 1 1 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Thioredoxin_3 PF13192.6 KXS13824.1 - 0.032 14.3 0.0 0.12 12.5 0.0 1.9 1 0 0 1 1 1 0 Thioredoxin domain Thioredoxin_9 PF14595.6 KXS13824.1 - 0.052 13.3 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin FAD_binding_3 PF01494.19 KXS13824.1 - 0.36 10.0 2.3 3.6 6.7 0.3 2.5 2 1 0 2 2 2 0 FAD binding domain Cullin_binding PF03556.15 KXS13825.1 - 5.4e-20 72.0 0.2 6.7e-20 71.7 0.2 1.1 1 0 0 1 1 1 1 Cullin binding DUF543 PF04418.12 KXS13826.1 - 2.8e-21 75.3 0.1 3.3e-21 75.0 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) Rhodanese PF00581.20 KXS13827.1 - 1.3e-12 48.2 0.0 1.6e-12 47.9 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain RsfS PF02410.15 KXS13832.1 - 0.002 18.5 0.0 0.0057 17.1 0.0 1.7 2 0 0 2 2 2 1 Ribosomal silencing factor during starvation Glyoxalase PF00903.25 KXS13833.1 - 0.015 15.5 0.0 3.6 7.8 0.0 2.3 1 1 1 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 2H-phosphodiest PF08975.10 KXS13834.1 - 0.039 13.9 0.0 0.058 13.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1868) DUF2849 PF11011.8 KXS13834.1 - 0.19 12.4 0.0 0.31 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2849) F-box-like PF12937.7 KXS13835.1 - 2.4e-08 33.8 0.5 6.4e-08 32.4 0.0 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KXS13835.1 - 7.8e-06 25.6 0.0 1.9e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 F-box domain RhoGAP PF00620.27 KXS13836.1 - 1.3e-18 67.3 0.1 1.4e-18 67.2 0.1 1.0 1 0 0 1 1 1 1 RhoGAP domain Tropomyosin PF00261.20 KXS13837.1 - 0.044 13.1 4.2 0.066 12.6 4.2 1.2 1 0 0 1 1 1 0 Tropomyosin BBP1_C PF15272.6 KXS13837.1 - 0.054 13.3 0.1 0.089 12.6 0.1 1.3 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal Aldo_ket_red PF00248.21 KXS13843.1 - 1.9e-14 53.5 0.0 2.6e-14 53.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family UPF0020 PF01170.18 KXS13844.1 - 5.9e-10 39.2 0.0 6.7e-09 35.7 0.0 2.2 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 DUF43 PF01861.16 KXS13844.1 - 0.0028 16.9 0.0 0.0057 15.9 0.0 1.4 1 0 0 1 1 1 1 Branched-chain polyamine synthase A C-terminal domain N6_Mtase PF02384.16 KXS13844.1 - 0.0063 15.8 0.0 0.27 10.5 0.0 2.1 2 0 0 2 2 2 1 N-6 DNA Methylase N6_N4_Mtase PF01555.18 KXS13844.1 - 0.0075 16.0 0.0 1.1 8.9 0.0 2.3 2 0 0 2 2 2 2 DNA methylase DUF3597 PF12200.8 KXS13844.1 - 0.17 12.4 1.3 5.8 7.5 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3597) T2SSM PF04612.12 KXS13845.1 - 1.5 8.9 5.7 2.5 8.1 5.7 1.3 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M CMS1 PF14617.6 KXS13847.1 - 0.13 11.6 0.0 0.16 11.3 0.0 1.1 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit adh_short PF00106.25 KXS13849.1 - 2.7e-34 118.3 0.0 3.6e-34 118.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXS13849.1 - 3e-22 79.3 0.0 4.3e-22 78.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXS13849.1 - 2.8e-09 37.2 0.0 5.3e-09 36.2 0.0 1.4 1 1 0 1 1 1 1 KR domain tRNA-synt_2b PF00587.25 KXS13850.1 - 1.5e-34 119.6 0.0 2.9e-34 118.6 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KXS13850.1 - 7.2e-17 61.3 0.1 1.5e-16 60.3 0.1 1.6 1 0 0 1 1 1 1 Anticodon binding domain TGS PF02824.21 KXS13850.1 - 3.8e-12 46.1 0.0 7.1e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 TGS domain tRNA_SAD PF07973.14 KXS13850.1 - 6.4e-12 45.4 0.0 1.5e-11 44.2 0.0 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain Hid1 PF12722.7 KXS13851.1 - 1.2e-23 83.2 0.8 4.9e-16 58.1 0.1 2.0 1 1 1 2 2 2 2 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 KXS13851.1 - 5.4e-12 44.9 0.0 6.8e-12 44.6 0.0 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Hid1 PF12722.7 KXS13852.1 - 7e-44 150.2 0.0 9.3e-44 149.8 0.0 1.1 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 KXS13852.1 - 3.7e-29 101.6 0.0 4.5e-29 101.4 0.0 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Cmc1 PF08583.10 KXS13853.1 - 3.4e-09 36.6 3.4 4e-09 36.4 3.4 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CX9C PF16860.5 KXS13853.1 - 0.0022 18.0 3.6 0.22 11.5 0.1 2.1 2 0 0 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, NDUF_B7 PF05676.13 KXS13853.1 - 0.014 15.1 6.2 0.015 15.0 6.2 1.1 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) GCK PF07802.11 KXS13853.1 - 0.021 15.3 2.5 0.039 14.4 2.5 1.4 1 1 0 1 1 1 0 GCK domain DHR-2 PF06920.13 KXS13853.1 - 0.049 12.3 0.7 0.056 12.1 0.7 1.0 1 0 0 1 1 1 0 Dock homology region 2 DUF3128 PF11326.8 KXS13853.1 - 0.072 13.5 3.8 0.35 11.3 3.7 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3128) Pet191_N PF10203.9 KXS13853.1 - 0.15 12.4 5.2 3.2 8.1 0.9 2.0 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 CHCH PF06747.13 KXS13853.1 - 0.17 12.0 4.6 0.49 10.6 0.8 2.2 2 0 0 2 2 2 0 CHCH domain HD_3 PF13023.6 KXS13854.1 - 1.1e-40 139.3 0.3 1.3e-40 139.1 0.3 1.1 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 KXS13854.1 - 6.8e-12 45.5 0.1 9.9e-12 45.0 0.1 1.3 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 KXS13854.1 - 6.2e-06 26.4 1.2 2e-05 24.8 1.2 1.9 1 1 0 1 1 1 1 HD domain F-box-like PF12937.7 KXS13855.1 - 0.0018 18.1 1.0 0.018 15.0 0.2 2.7 2 0 0 2 2 2 1 F-box-like NumbF PF06311.12 KXS13855.1 - 0.06 13.9 0.0 0.21 12.2 0.0 1.9 1 0 0 1 1 1 0 NUMB domain F-box_5 PF18511.1 KXS13855.1 - 0.11 12.1 0.8 0.88 9.2 0.4 2.6 2 0 0 2 2 2 0 F-box Peptidase_M17 PF00883.21 KXS13856.1 - 8.6e-116 386.6 0.0 1.1e-115 386.1 0.0 1.2 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.17 KXS13856.1 - 3.6e-09 36.5 0.8 1.5e-08 34.5 0.2 2.2 2 1 0 2 2 2 1 Cytosol aminopeptidase family, N-terminal domain DUF4201 PF13870.6 KXS13857.1 - 2.4e-40 138.1 8.1 2.4e-40 138.1 8.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4201) MscS_porin PF12795.7 KXS13857.1 - 0.0046 16.5 1.1 0.0046 16.5 1.1 3.8 3 2 0 3 3 3 1 Mechanosensitive ion channel porin domain Spc7 PF08317.11 KXS13857.1 - 0.007 15.3 0.3 0.007 15.3 0.3 3.1 2 1 0 3 3 3 1 Spc7 kinetochore protein APG6_N PF17675.1 KXS13857.1 - 0.023 15.2 22.7 0.4 11.2 6.9 3.1 2 1 0 2 2 2 0 Apg6 coiled-coil region HIP1_clath_bdg PF16515.5 KXS13857.1 - 0.18 12.4 20.0 1.8 9.3 0.2 3.7 3 1 1 4 4 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 THOC7 PF05615.13 KXS13857.1 - 0.21 11.8 24.5 1.3 9.3 1.6 4.2 4 0 0 4 4 4 0 Tho complex subunit 7 UPF0242 PF06785.11 KXS13857.1 - 1.4 9.0 17.6 1.9 8.6 11.0 2.3 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF4200 PF13863.6 KXS13857.1 - 2.1 8.8 21.6 2.5 8.5 14.2 3.5 2 2 1 3 3 3 0 Domain of unknown function (DUF4200) TPR_MLP1_2 PF07926.12 KXS13857.1 - 4 7.5 31.6 1.8 8.6 8.4 4.4 3 2 1 4 4 4 0 TPR/MLP1/MLP2-like protein Occludin_ELL PF07303.13 KXS13857.1 - 4.8 8.0 15.8 3.5 8.4 0.4 3.3 2 1 0 2 2 2 0 Occludin homology domain RGS PF00615.19 KXS13859.1 - 2.1e-08 34.4 0.2 0.00027 21.2 0.0 2.5 2 1 0 2 2 2 2 Regulator of G protein signaling domain Tom22 PF04281.13 KXS13861.1 - 6.7e-28 97.2 1.5 8.9e-28 96.8 1.5 1.1 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 PBP1_TM PF14812.6 KXS13861.1 - 0.091 13.1 0.9 0.12 12.7 0.9 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PI3K_1B_p101 PF10486.9 KXS13861.1 - 0.24 9.1 0.4 0.28 8.9 0.4 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DUF5572 PF17733.1 KXS13862.1 - 1.2e-20 73.1 0.4 1.2e-20 73.1 0.4 2.0 2 0 0 2 2 2 1 Family of unknown function (DUF5572) NDK PF00334.19 KXS13864.1 - 1.5e-42 144.9 0.0 1.9e-42 144.4 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Dpy-30 PF05186.13 KXS13864.1 - 2.4e-13 49.5 0.2 4e-13 48.8 0.2 1.3 1 0 0 1 1 1 1 Dpy-30 motif T2SSG PF08334.11 KXS13864.1 - 0.1 12.7 0.1 0.18 11.9 0.1 1.3 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein G FeoB_associated PF12669.7 KXS13865.1 - 8.8 6.8 10.0 15 6.1 0.2 2.7 3 0 0 3 3 3 0 FeoB-associated Cys-rich membrane protein DUF863 PF05904.11 KXS13866.1 - 0.17 10.3 3.4 0.21 10.0 3.4 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF863) Vps39_1 PF10366.9 KXS13868.1 - 3.4e-23 82.0 0.0 2.7e-22 79.1 0.0 2.3 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.9 KXS13868.1 - 6.7e-17 61.9 1.7 1.3e-16 61.0 0.2 2.1 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 ANAPC4_WD40 PF12894.7 KXS13868.1 - 1.9e-06 28.1 0.0 6 7.2 0.0 4.7 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KXS13868.1 - 0.00015 22.5 12.1 0.12 13.3 0.6 5.7 6 0 0 6 6 6 2 WD domain, G-beta repeat Clathrin PF00637.20 KXS13868.1 - 0.0015 18.4 0.0 0.0097 15.8 0.0 2.1 2 0 0 2 2 2 1 Region in Clathrin and VPS Vac7 PF12751.7 KXS13868.1 - 0.46 9.9 5.6 0.92 8.9 5.6 1.4 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 FRG2 PF15315.6 KXS13868.1 - 3 8.0 10.8 0.16 12.1 4.0 2.3 3 0 0 3 3 3 0 Facioscapulohumeral muscular dystrophy candidate 2 Ank_3 PF13606.6 KXS13869.1 - 3.2e-07 30.1 0.0 0.0093 16.4 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat SH3_9 PF14604.6 KXS13869.1 - 1.1e-06 28.4 0.0 2.4e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Ank_2 PF12796.7 KXS13869.1 - 2.3e-06 28.1 0.0 3.8e-05 24.2 0.0 2.6 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) SH3_1 PF00018.28 KXS13869.1 - 5.1e-05 22.8 0.0 9.3e-05 22.0 0.0 1.5 1 0 0 1 1 1 1 SH3 domain Ank_4 PF13637.6 KXS13869.1 - 0.00036 21.1 0.0 0.013 16.1 0.0 3.1 3 1 0 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 KXS13869.1 - 0.00063 20.1 0.0 0.8 10.3 0.0 3.6 3 0 0 3 3 3 1 Ankyrin repeat Filament PF00038.21 KXS13869.1 - 0.0014 18.3 5.0 0.0023 17.6 5.0 1.3 1 0 0 1 1 1 1 Intermediate filament protein SH3_2 PF07653.17 KXS13869.1 - 0.0036 17.0 0.0 0.0073 16.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Ank_5 PF13857.6 KXS13869.1 - 0.0059 16.9 0.0 0.41 11.0 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) ATG16 PF08614.11 KXS13869.1 - 0.1 12.8 10.2 1.7 8.9 1.1 2.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF3450 PF11932.8 KXS13869.1 - 0.1 11.9 4.3 4.1 6.7 1.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) CENP-F_leu_zip PF10473.9 KXS13869.1 - 0.19 11.7 8.0 0.34 10.9 8.0 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ADIP PF11559.8 KXS13869.1 - 0.2 11.7 9.9 0.56 10.3 2.9 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding BLOC1_2 PF10046.9 KXS13869.1 - 0.25 11.7 2.4 0.66 10.3 0.1 2.3 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Sec2p PF06428.11 KXS13869.1 - 0.7 9.9 5.4 8.1 6.5 0.3 2.4 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p DHR10 PF18595.1 KXS13869.1 - 0.93 9.6 11.7 0.16 12.1 3.7 2.3 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain Cluap1 PF10234.9 KXS13869.1 - 1.1 8.6 8.1 2.4 7.5 8.2 1.6 1 1 0 1 1 1 0 Clusterin-associated protein-1 ZapB PF06005.12 KXS13869.1 - 1.8 9.1 11.0 1.5 9.3 1.0 2.3 2 0 0 2 2 2 0 Cell division protein ZapB SlyX PF04102.12 KXS13869.1 - 2.2 8.9 5.8 14 6.4 0.6 2.6 2 0 0 2 2 2 0 SlyX YabA PF06156.13 KXS13869.1 - 6 7.6 7.2 8.2 7.1 1.8 2.4 1 1 1 2 2 2 0 Initiation control protein YabA SnoaL_2 PF12680.7 KXS13870.1 - 0.00093 19.8 0.1 0.0015 19.2 0.1 1.3 1 0 0 1 1 1 1 SnoaL-like domain CCT PF06203.14 KXS13870.1 - 0.08 13.0 0.5 0.13 12.4 0.5 1.3 1 0 0 1 1 1 0 CCT motif Rcd1 PF04078.13 KXS13871.1 - 5.8e-122 406.0 0.0 6.5e-122 405.8 0.0 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like UCH PF00443.29 KXS13872.1 - 4.2e-32 111.7 0.0 5.8e-32 111.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KXS13872.1 - 3.3e-12 46.6 0.5 6.2e-12 45.7 0.5 1.4 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 KXS13872.1 - 0.038 13.6 0.0 0.3 10.6 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase FliT PF05400.13 KXS13873.1 - 0.025 15.4 6.3 0.025 15.4 6.3 1.8 1 1 1 2 2 2 0 Flagellar protein FliT ATG16 PF08614.11 KXS13873.1 - 0.11 12.8 12.3 0.032 14.4 9.7 1.4 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) GAS PF13851.6 KXS13873.1 - 0.11 11.9 7.6 0.22 10.8 5.6 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF1664 PF07889.12 KXS13873.1 - 0.33 11.0 3.6 1.9 8.5 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Macoilin PF09726.9 KXS13873.1 - 1.2 7.7 9.2 3.3 6.2 9.4 1.5 1 1 0 1 1 1 0 Macoilin family Lung_7-TM_R PF06814.13 KXS13874.1 - 4.4e-69 233.0 17.7 5.3e-69 232.7 17.7 1.0 1 0 0 1 1 1 1 Lung seven transmembrane receptor 2-Hacid_dh_C PF02826.19 KXS13875.1 - 2e-46 157.6 0.0 2.8e-46 157.1 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KXS13875.1 - 2e-15 56.6 0.0 2.6e-15 56.2 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KXS13875.1 - 0.016 15.4 0.0 0.024 14.8 0.0 1.2 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 4HBT_3 PF13622.6 KXS13876.1 - 0.0022 18.3 0.0 0.0024 18.2 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily CBS PF00571.28 KXS13877.1 - 6e-32 109.9 0.1 1.4e-09 38.2 0.1 4.3 4 0 0 4 4 4 4 CBS domain Med26 PF08711.11 KXS13878.1 - 1.8e-11 43.9 0.1 4.3e-11 42.7 0.1 1.7 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Ku_C PF03730.14 KXS13878.1 - 1.9 9.3 0.0 1.9 9.3 0.0 4.4 3 2 0 3 3 3 0 Ku70/Ku80 C-terminal arm Tctex-1 PF03645.13 KXS13879.1 - 6.3e-25 87.4 0.0 8.5e-25 87.0 0.0 1.2 1 0 0 1 1 1 1 Tctex-1 family Sld5 PF05916.11 KXS13879.1 - 0.022 15.2 0.1 0.036 14.5 0.1 1.3 1 0 0 1 1 1 0 GINS complex protein Speriolin_C PF15059.6 KXS13879.1 - 0.042 14.0 0.1 0.061 13.4 0.1 1.2 1 0 0 1 1 1 0 Speriolin C-terminus PG_binding_4 PF12229.8 KXS13879.1 - 0.076 13.3 0.4 0.11 12.8 0.4 1.2 1 0 0 1 1 1 0 Putative peptidoglycan binding domain Ribosomal_L36 PF00444.18 KXS13880.1 - 1.5e-18 66.7 8.2 2.3e-18 66.1 8.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L36 DUF4761 PF15958.5 KXS13880.1 - 0.073 13.2 0.1 3.3 7.9 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4761) RasGEF PF00617.19 KXS13881.1 - 9.5e-46 156.2 0.0 1.7e-45 155.4 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain zf-C2H2_jaz PF12171.8 KXS13882.1 - 2.7e-08 33.9 1.7 4.1e-08 33.3 1.7 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding FidL_like PF15941.5 KXS13882.1 - 0.046 14.2 0.2 0.96 9.9 0.0 2.0 2 0 0 2 2 2 0 FidL-like putative membrane protein zf-C2H2 PF00096.26 KXS13882.1 - 0.048 14.1 0.8 0.093 13.2 0.8 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_3rep PF18868.1 KXS13882.1 - 0.049 14.3 0.3 0.082 13.6 0.1 1.4 2 0 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats ArfGap PF01412.18 KXS13882.1 - 0.54 10.3 2.7 0.86 9.7 0.8 2.1 2 1 0 2 2 2 0 Putative GTPase activating protein for Arf C2 PF00168.30 KXS13883.1 - 9.7e-21 74.0 0.0 1.3e-20 73.6 0.0 1.2 1 0 0 1 1 1 1 C2 domain C2 PF00168.30 KXS13884.1 - 9.2e-12 45.2 0.1 3e-11 43.5 0.0 1.9 2 0 0 2 2 2 1 C2 domain EF-hand_6 PF13405.6 KXS13884.1 - 0.061 13.3 0.2 1.1 9.4 0.0 2.6 3 0 0 3 3 3 0 EF-hand domain PS_Dcarbxylase PF02666.15 KXS13885.1 - 2.1e-54 184.1 0.1 3e-54 183.6 0.1 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase POR_N PF01855.19 KXS13885.1 - 0.14 11.9 0.1 0.23 11.2 0.1 1.2 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Myb_DNA-binding PF00249.31 KXS13886.1 - 0.00014 22.0 0.0 0.00033 20.8 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF2730 PF10805.8 KXS13886.1 - 0.022 14.9 0.9 0.036 14.2 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) Nucleoporin_FG2 PF15967.5 KXS13886.1 - 0.41 9.1 1.2 0.52 8.8 1.2 1.1 1 0 0 1 1 1 0 Nucleoporin FG repeated region Acetyltransf_1 PF00583.25 KXS13887.1 - 3.8e-19 69.1 0.0 4.7e-19 68.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXS13887.1 - 3.4e-12 46.6 0.0 4.7e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KXS13887.1 - 8e-12 45.2 0.0 9.5e-12 45.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXS13887.1 - 7.5e-08 32.2 0.1 1.1e-07 31.7 0.1 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.6 KXS13887.1 - 3.9e-05 23.3 0.0 5.6e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KXS13887.1 - 4.5e-05 24.2 0.0 6.7e-05 23.6 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KXS13887.1 - 0.0016 18.5 0.0 0.0058 16.7 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KXS13887.1 - 0.0044 17.2 0.0 0.0054 16.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KXS13887.1 - 0.0083 16.2 0.0 0.014 15.5 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase LRR_8 PF13855.6 KXS13888.1 - 1.7e-13 50.1 5.3 7e-07 28.9 1.5 2.9 2 2 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 KXS13888.1 - 4.6e-11 42.8 6.1 0.022 15.2 0.1 4.3 2 1 3 5 5 5 5 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KXS13888.1 - 0.0039 17.1 0.2 0.12 12.5 0.0 3.2 3 0 0 3 3 3 1 Leucine Rich repeat LRR_9 PF14580.6 KXS13888.1 - 0.067 12.7 0.3 0.34 10.4 0.0 2.0 1 1 1 2 2 2 0 Leucine-rich repeat LRR_1 PF00560.33 KXS13888.1 - 5.5 7.9 7.6 1.7 9.5 0.2 3.7 4 1 0 4 4 4 0 Leucine Rich Repeat AAA PF00004.29 KXS13889.1 - 2.1e-41 141.5 0.0 3.8e-41 140.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KXS13889.1 - 1.1e-07 31.5 0.1 2.4e-07 30.4 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 KXS13889.1 - 2.6e-05 24.2 0.0 0.0001 22.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KXS13889.1 - 7.6e-05 23.0 0.0 0.005 17.1 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 KXS13889.1 - 0.00014 22.3 0.1 0.0013 19.1 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain AAA_2 PF07724.14 KXS13889.1 - 0.00021 21.4 0.0 0.00074 19.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 KXS13889.1 - 0.00047 19.4 0.0 0.00088 18.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 KXS13889.1 - 0.003 17.3 0.0 0.0063 16.3 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 KXS13889.1 - 0.0094 15.5 0.0 0.023 14.2 0.0 1.6 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_28 PF13521.6 KXS13889.1 - 0.015 15.5 0.0 0.026 14.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KXS13889.1 - 0.018 15.2 0.0 0.038 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KXS13889.1 - 0.032 14.6 0.0 0.083 13.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_3 PF07726.11 KXS13889.1 - 0.034 14.0 0.0 0.07 13.0 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.13 KXS13889.1 - 0.039 13.2 0.0 0.087 12.0 0.0 1.5 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_24 PF13479.6 KXS13889.1 - 0.039 13.7 0.1 0.14 11.8 0.0 1.9 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 KXS13889.1 - 0.043 13.7 0.0 5.7 6.8 0.0 2.4 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea AAA_18 PF13238.6 KXS13889.1 - 0.05 14.1 0.1 0.14 12.7 0.0 1.9 2 0 0 2 2 1 0 AAA domain Sigma54_activ_2 PF14532.6 KXS13889.1 - 0.054 13.6 0.0 0.15 12.2 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain Mg_chelatase PF01078.21 KXS13889.1 - 0.056 12.8 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 KXS13889.1 - 0.074 12.8 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain IstB_IS21 PF01695.17 KXS13889.1 - 0.12 12.1 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_14 PF13173.6 KXS13889.1 - 0.15 12.1 0.0 0.29 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain XPG_I_2 PF12813.7 KXS13890.1 - 0.0053 16.3 0.0 0.01 15.4 0.0 1.4 1 0 0 1 1 1 1 XPG domain containing BPL_LplA_LipB_2 PF16917.5 KXS13890.1 - 0.11 12.0 0.0 0.26 10.8 0.0 1.5 1 0 0 1 1 1 0 Biotin/lipoate A/B protein ligase family GHMP_kinases_C PF08544.13 KXS13890.1 - 0.17 12.3 0.2 0.53 10.7 0.2 1.8 1 0 0 1 1 1 0 GHMP kinases C terminal RNase_H PF00075.24 KXS13891.1 - 0.031 14.5 0.0 0.047 13.9 0.0 1.3 1 0 0 1 1 1 0 RNase H Mcp5_PH PF12814.7 KXS13892.1 - 1.4e-17 64.0 0.2 5.2e-17 62.1 0.2 2.0 1 1 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology ERM PF00769.19 KXS13892.1 - 3.8e-05 23.6 20.6 0.00017 21.5 10.0 3.1 3 0 0 3 3 3 2 Ezrin/radixin/moesin family PH PF00169.29 KXS13892.1 - 0.014 15.9 0.3 0.06 13.9 0.0 2.2 2 0 0 2 2 2 0 PH domain APG6_N PF17675.1 KXS13892.1 - 0.2 12.2 20.1 0.48 10.9 0.1 3.4 3 0 0 3 3 3 0 Apg6 coiled-coil region HALZ PF02183.18 KXS13892.1 - 3.4 8.0 7.9 1.8 8.8 3.8 2.4 2 0 0 2 2 2 0 Homeobox associated leucine zipper KASH_CCD PF14662.6 KXS13892.1 - 8.9 6.1 17.4 3.3 7.5 7.5 2.7 3 0 0 3 3 3 0 Coiled-coil region of CCDC155 or KASH p450 PF00067.22 KXS13893.1 - 1.6e-34 119.5 0.0 2e-34 119.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KXS13894.1 - 8.2e-06 24.8 0.0 0.00047 19.0 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 eIF-3c_N PF05470.12 KXS13894.1 - 0.00016 20.1 0.0 0.18 10.1 0.0 2.0 2 0 0 2 2 2 2 Eukaryotic translation initiation factor 3 subunit 8 N-terminus RVT_1 PF00078.27 KXS13894.1 - 0.1 12.1 0.0 0.82 9.1 0.0 2.0 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) Abhydrolase_3 PF07859.13 KXS13895.1 - 5.1e-55 186.6 0.1 6.1e-55 186.3 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KXS13895.1 - 3.5e-07 29.5 0.0 9e-07 28.1 0.0 1.5 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 KXS13895.1 - 3.8e-06 26.5 0.0 4.7e-05 22.9 0.0 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family AXE1 PF05448.12 KXS13895.1 - 0.0033 16.1 0.2 0.0072 15.0 0.1 1.5 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) Chlorophyllase2 PF12740.7 KXS13895.1 - 0.15 10.9 0.0 0.26 10.2 0.0 1.3 1 1 0 1 1 1 0 Chlorophyllase enzyme Abhydrolase_3 PF07859.13 KXS13896.1 - 1.3e-24 87.2 1.2 1.8e-13 50.9 0.4 2.4 1 1 1 2 2 2 2 alpha/beta hydrolase fold TauD PF02668.16 KXS13897.1 - 9.2e-53 179.7 0.6 1.2e-52 179.4 0.6 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Glyco_hydro_2_N PF02837.18 KXS13897.1 - 0.068 13.1 0.0 0.12 12.2 0.0 1.4 2 0 0 2 2 2 0 Glycosyl hydrolases family 2, sugar binding domain Slx4 PF09494.10 KXS13898.1 - 1.1e-07 31.7 0.0 1.8e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Slx4 endonuclease Sgf11 PF08209.11 KXS13898.1 - 0.12 12.0 8.1 0.49 10.0 0.2 2.9 3 0 0 3 3 3 0 Sgf11 (transcriptional regulation protein) RNHCP PF12647.7 KXS13898.1 - 0.18 11.8 7.6 0.82 9.7 1.0 2.4 1 1 1 2 2 2 0 RNHCP domain zf-TFIIB PF13453.6 KXS13898.1 - 0.21 10.9 2.3 1.5 8.2 0.0 2.5 2 0 0 2 2 2 0 Transcription factor zinc-finger zf-CpG_bind_C PF12269.8 KXS13898.1 - 0.24 11.1 1.6 0.43 10.3 1.0 1.7 1 1 1 2 2 2 0 CpG binding protein zinc finger C terminal domain RNF220 PF15926.5 KXS13898.1 - 0.63 9.6 2.4 2.2 7.8 0.2 2.6 2 1 1 3 3 3 0 E3 ubiquitin-protein ligase RNF220 zinc-ribbons_6 PF07191.12 KXS13898.1 - 1.7 8.7 3.6 9.6 6.3 1.3 2.4 2 1 0 2 2 2 0 zinc-ribbons Ribosomal_L13 PF00572.18 KXS13899.1 - 2.2e-46 157.2 0.0 2.5e-46 157.0 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L13 UTP15_C PF09384.10 KXS13900.1 - 4.1e-44 149.8 0.3 6.5e-44 149.2 0.3 1.3 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.32 KXS13900.1 - 1.8e-23 82.3 7.1 0.00014 22.6 0.2 7.5 8 0 0 8 8 8 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXS13900.1 - 3.4e-08 33.7 0.0 0.1 12.9 0.0 4.2 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Gmad1 PF10647.9 KXS13900.1 - 0.05 13.4 1.7 0.13 12.0 0.4 2.1 2 0 0 2 2 2 0 Lipoprotein LpqB beta-propeller domain PALB2_WD40 PF16756.5 KXS13900.1 - 0.11 11.4 0.1 0.19 10.6 0.1 1.3 1 0 0 1 1 1 0 Partner and localizer of BRCA2 WD40 domain BBS2_Mid PF14783.6 KXS13900.1 - 0.11 12.5 0.0 9.5 6.3 0.1 3.0 2 1 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region Oest_recep PF02159.15 KXS13900.1 - 0.13 12.8 0.0 0.23 12.0 0.0 1.4 1 0 0 1 1 1 0 Oestrogen receptor NmrA PF05368.13 KXS13901.1 - 9.5e-35 120.2 0.0 1.4e-34 119.7 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXS13901.1 - 3.4e-13 49.9 0.0 4.8e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KXS13901.1 - 0.00036 20.1 0.0 0.0032 17.0 0.0 2.3 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXS13901.1 - 0.18 10.8 0.0 0.28 10.2 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Ank_3 PF13606.6 KXS13902.1 - 0.00024 21.3 0.6 0.12 13.0 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 KXS13902.1 - 0.0008 20.0 0.0 0.62 10.7 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KXS13902.1 - 0.0064 16.9 1.4 0.39 11.3 0.3 2.6 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 KXS13902.1 - 0.022 15.1 0.1 11 6.5 0.0 2.5 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXS13902.1 - 0.04 14.5 0.0 8.6 7.1 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Seipin PF06775.14 KXS13904.1 - 1.9e-30 106.5 0.0 2.9e-30 105.9 0.0 1.3 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) DUF5600 PF18150.1 KXS13905.1 - 0.0016 19.0 0.0 0.0029 18.2 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF5600) Pkinase_Tyr PF07714.17 KXS13906.1 - 1.6e-30 106.3 0.0 5.9e-30 104.4 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXS13906.1 - 1.7e-30 106.3 0.0 6e-30 104.5 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KXS13906.1 - 0.0024 17.2 0.0 0.0036 16.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KXS13906.1 - 0.01 14.7 0.0 0.014 14.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 KXS13906.1 - 0.029 14.0 0.0 0.048 13.3 0.0 1.3 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 KXS13906.1 - 0.07 13.0 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-PolyVal PF18762.1 KXS13906.1 - 0.17 11.8 0.0 0.27 11.2 0.0 1.2 1 0 0 1 1 1 0 Serine/Threonine/Tyrosine Kinase found in polyvalent proteins Y_phosphatase2 PF03162.13 KXS13908.1 - 2.1e-59 199.8 0.0 2.3e-59 199.7 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 KXS13908.1 - 3.8e-06 27.0 0.0 6e-06 26.4 0.0 1.4 1 1 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 KXS13908.1 - 0.026 14.3 0.0 0.032 14.0 0.0 1.2 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KXS13908.1 - 0.15 11.6 0.0 0.18 11.4 0.0 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase CRT10 PF08728.10 KXS13909.1 - 0.16 10.1 0.0 0.21 9.7 0.0 1.1 1 0 0 1 1 1 0 CRT10 DUF4551 PF15087.6 KXS13909.1 - 0.34 9.7 4.2 0.39 9.5 4.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Dicer_dimer PF03368.14 KXS13911.1 - 8.9e-19 67.4 0.0 2.2e-18 66.2 0.0 1.7 1 0 0 1 1 1 1 Dicer dimerisation domain Helicase_C PF00271.31 KXS13911.1 - 5.5e-15 55.7 0.0 1.4e-14 54.3 0.0 1.7 1 1 0 1 1 1 1 Helicase conserved C-terminal domain Ribonuclease_3 PF00636.26 KXS13911.1 - 1e-12 48.6 0.0 2.7e-12 47.2 0.0 1.8 1 0 0 1 1 1 1 Ribonuclease III domain ResIII PF04851.15 KXS13911.1 - 9e-12 45.3 0.0 1.8e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Ribonucleas_3_3 PF14622.6 KXS13911.1 - 8.4e-10 38.9 0.0 1.3e-06 28.6 0.0 3.0 3 0 0 3 3 3 2 Ribonuclease-III-like DEAD PF00270.29 KXS13911.1 - 1.1e-09 38.4 0.0 2.5e-09 37.1 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KXS13911.1 - 0.13 12.6 0.0 0.29 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain dsrm PF00035.26 KXS13912.1 - 0.00011 22.8 0.1 0.00027 21.6 0.1 1.8 1 1 0 1 1 1 1 Double-stranded RNA binding motif Ribonuclease_3 PF00636.26 KXS13912.1 - 0.00019 22.0 0.0 0.00043 20.9 0.0 1.7 1 0 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KXS13912.1 - 0.0048 17.0 0.0 0.01 16.0 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease-III-like DUF4443 PF14544.6 KXS13912.1 - 0.042 14.1 0.0 0.084 13.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4443) Carboxyl_trans PF01039.22 KXS13913.1 - 4.4e-68 230.1 0.0 5.6e-68 229.8 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain SH3_9 PF14604.6 KXS13914.1 - 0.00031 20.5 0.0 0.00055 19.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXS13914.1 - 0.0031 17.1 0.0 0.0048 16.5 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KXS13914.1 - 0.03 14.0 0.0 0.043 13.5 0.0 1.2 1 0 0 1 1 1 0 Variant SH3 domain LRR_8 PF13855.6 KXS13915.1 - 1.5e-06 27.9 0.1 2.6e-06 27.1 0.1 1.3 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 KXS13915.1 - 3.3e-05 24.2 1.3 0.0024 18.2 0.1 2.3 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KXS13915.1 - 0.039 14.5 0.7 4.6 8.2 0.0 3.1 3 0 0 3 3 3 0 Leucine Rich Repeat PAC4 PF16093.5 KXS13916.1 - 1.7e-11 44.2 0.0 1.7e-11 44.2 0.0 1.5 2 0 0 2 2 2 1 Proteasome assembly chaperone 4 TPR_1 PF00515.28 KXS13917.1 - 1.4e-12 46.8 0.5 5.5e-08 32.3 0.1 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 KXS13917.1 - 1.9e-11 43.4 0.3 1.2e-07 31.2 0.0 2.3 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.17 KXS13917.1 - 1.5e-10 40.3 4.3 1.4e-06 27.9 0.1 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KXS13917.1 - 3e-08 33.2 1.4 0.00055 19.9 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KXS13917.1 - 3.5e-08 33.9 0.1 3.5e-08 33.9 0.1 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 KXS13917.1 - 3.7e-06 27.0 0.4 8.5e-06 25.8 0.4 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.6 KXS13917.1 - 7.4e-05 22.9 0.1 0.0028 17.9 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 KXS13917.1 - 8.3e-05 23.1 3.8 0.42 11.6 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KXS13917.1 - 0.00038 20.7 0.0 0.00086 19.6 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.6 KXS13917.1 - 0.00089 19.7 4.2 0.0031 18.0 0.2 2.7 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 KXS13917.1 - 0.06 14.0 0.1 5.2 7.9 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 KXS13917.1 - 0.081 12.8 0.1 0.46 10.4 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 KXS13917.1 - 0.087 12.9 0.1 1.2 9.3 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Sigma_reg_N PF13800.6 KXS13918.1 - 0.037 14.3 0.2 0.056 13.7 0.2 1.3 1 0 0 1 1 1 0 Sigma factor regulator N-terminal MOR2-PAG1_N PF14222.6 KXS13920.1 - 4.4e-104 349.4 0.0 6.3e-85 286.2 0.0 2.3 1 1 0 2 2 2 2 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.6 KXS13920.1 - 3.1e-59 200.9 0.0 3.1e-58 197.6 0.0 2.7 2 0 0 2 2 2 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.6 KXS13920.1 - 1.1e-24 86.3 0.3 2e-16 58.9 0.0 3.1 3 1 0 3 3 3 2 Cell morphogenesis central region HEAT_2 PF13646.6 KXS13920.1 - 0.001 19.4 1.0 1.8 9.0 0.0 4.9 4 0 0 4 4 4 1 HEAT repeats HEAT PF02985.22 KXS13920.1 - 0.0018 18.4 7.0 3.1 8.3 0.1 6.1 5 0 0 5 5 5 1 HEAT repeat Arm PF00514.23 KXS13920.1 - 0.19 11.8 4.8 27 5.0 0.1 3.8 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat F-box-like PF12937.7 KXS13921.1 - 8.3e-06 25.6 0.1 1.5e-05 24.7 0.1 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXS13921.1 - 0.11 12.5 0.8 0.36 10.8 0.8 1.8 1 1 0 1 1 1 0 F-box domain SPX PF03105.19 KXS13921.1 - 0.15 11.9 4.1 0.18 11.7 4.1 1.1 1 0 0 1 1 1 0 SPX domain SOG2 PF10428.9 KXS13921.1 - 1.2 8.3 8.7 1.5 8.0 8.7 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DUF775 PF05603.12 KXS13922.1 - 1.4e-40 139.0 0.0 1.6e-40 138.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF775) Pkinase_Tyr PF07714.17 KXS13924.1 - 1.5e-06 27.7 0.0 1.6e-06 27.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXS13924.1 - 0.0078 15.6 0.0 0.0091 15.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain DNA_pol_B_palm PF14792.6 KXS13925.1 - 6.5e-26 90.8 0.0 1.2e-25 89.9 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.6 KXS13925.1 - 1.3e-23 82.9 0.4 9.4e-23 80.2 0.0 2.5 3 0 0 3 3 3 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.9 KXS13925.1 - 7.4e-18 64.1 0.1 2.1e-17 62.7 0.1 1.9 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.6 KXS13925.1 - 2.7e-14 53.3 0.1 1.2e-13 51.2 0.1 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix domain NTP_transf_2 PF01909.23 KXS13925.1 - 0.0018 18.5 0.0 0.0046 17.2 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain HHH_2 PF12826.7 KXS13925.1 - 0.037 14.1 0.0 0.37 10.9 0.0 2.6 2 0 0 2 2 2 0 Helix-hairpin-helix motif SUFU PF05076.13 KXS13925.1 - 0.07 13.1 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Suppressor of fused protein (SUFU) Serglycin PF04360.12 KXS13925.1 - 3 7.8 12.6 19 5.2 12.6 2.2 1 1 0 1 1 1 0 Serglycin HgmA PF04209.13 KXS13927.1 - 2.8e-164 546.9 0.6 7e-164 545.5 0.6 1.5 1 1 0 1 1 1 1 homogentisate 1,2-dioxygenase CAP_N PF01213.19 KXS13929.1 - 0.11 11.9 12.7 0.14 11.6 12.7 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.11 KXS13929.1 - 2.2 8.3 10.1 2.7 8.0 10.1 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator PRIMA1 PF16101.5 KXS13929.1 - 8.4 6.5 17.9 12 5.9 17.9 1.2 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 DNA_pol_delta_4 PF04081.13 KXS13931.1 - 2e-22 79.9 0.4 2.4e-22 79.7 0.4 1.1 1 0 0 1 1 1 1 DNA polymerase delta, subunit 4 Atg14 PF10186.9 KXS13932.1 - 1.7e-15 56.9 0.0 3.6e-15 55.8 0.0 1.5 1 1 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 APG6 PF04111.12 KXS13932.1 - 3.2e-05 24.0 0.0 5e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Apg6 BARA domain GBP_C PF02841.14 KXS13932.1 - 0.99 8.8 7.1 1.6 8.0 7.1 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Ank_2 PF12796.7 KXS13933.1 - 2.5e-44 149.8 10.2 4e-10 40.2 0.0 6.5 1 1 5 7 7 7 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXS13933.1 - 5.8e-31 106.5 14.0 2.5e-06 27.9 0.0 8.4 4 3 5 9 9 9 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXS13933.1 - 1.9e-23 80.0 16.0 0.0068 16.8 0.0 11.8 12 0 0 12 12 12 5 Ankyrin repeat Ank PF00023.30 KXS13933.1 - 4.8e-21 74.2 31.8 0.0062 16.9 0.1 11.6 10 1 2 12 12 12 7 Ankyrin repeat Ank_5 PF13857.6 KXS13933.1 - 1.3e-19 70.0 26.7 3.7e-05 23.9 0.1 10.9 2 2 9 12 12 12 8 Ankyrin repeats (many copies) DUF4515 PF14988.6 KXS13934.1 - 8.9e-09 35.5 21.3 8.9e-09 35.5 21.3 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF4515) BRE PF06113.12 KXS13934.1 - 0.0059 15.5 2.9 0.95 8.2 0.0 3.3 3 0 0 3 3 3 2 Brain and reproductive organ-expressed protein (BRE) Cnd1_N PF12922.7 KXS13934.1 - 0.035 13.9 1.5 0.12 12.2 1.5 1.9 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1, N-term UCH PF00443.29 KXS13937.1 - 7.5e-61 205.9 0.0 9.1e-61 205.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KXS13937.1 - 1.3e-16 61.1 0.0 2.6e-14 53.6 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUF3138 PF11336.8 KXS13939.1 - 0.21 10.1 4.3 0.071 11.7 1.9 1.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) Pkinase PF00069.25 KXS13940.1 - 1.1e-11 44.6 0.0 1.5e-11 44.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS13940.1 - 0.00039 19.8 0.5 0.001 18.4 0.5 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase DUF4471 PF14740.6 KXS13940.1 - 0.079 12.2 0.0 0.17 11.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4471) DUF4413 PF14372.6 KXS13942.1 - 0.0037 17.6 0.8 0.0081 16.5 0.8 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4413) Ac76 PF05814.11 KXS13942.1 - 0.0065 16.4 0.6 0.013 15.5 0.6 1.4 1 0 0 1 1 1 1 Orf76 (Ac76) MerC PF03203.14 KXS13942.1 - 0.029 14.8 0.1 0.054 13.9 0.1 1.4 1 0 0 1 1 1 0 MerC mercury resistance protein Wx5_PLAF3D7 PF09688.10 KXS13942.1 - 0.14 12.1 5.5 0.51 10.3 5.5 1.9 1 1 0 1 1 1 0 Protein of unknown function (Wx5_PLAF3D7) Aminotran_1_2 PF00155.21 KXS13943.1 - 8.2e-41 140.4 0.0 1.1e-40 139.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 KXS13943.1 - 0.0015 17.8 0.0 0.0025 17.1 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase FdtA PF05523.11 KXS13943.1 - 0.025 14.3 0.0 0.052 13.3 0.0 1.5 1 0 0 1 1 1 0 WxcM-like, C-terminal Aminotran_MocR PF12897.7 KXS13943.1 - 0.16 10.7 0.0 0.22 10.2 0.0 1.2 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase FoP_duplication PF13865.6 KXS13943.1 - 3.7 8.2 8.9 6.6 7.4 8.9 1.4 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 TPR_1 PF00515.28 KXS13944.1 - 8.1e-13 47.6 0.5 0.0071 16.1 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KXS13944.1 - 1.3e-09 37.4 0.8 0.016 15.3 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat UBA PF00627.31 KXS13944.1 - 1e-05 25.3 0.0 2.5e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain TPR_16 PF13432.6 KXS13944.1 - 0.00025 21.6 4.2 0.002 18.7 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 KXS13944.1 - 0.011 16.0 2.9 0.22 11.8 2.3 2.9 2 1 0 2 2 2 0 Tetratricopeptide repeat DnaJ PF00226.31 KXS13944.1 - 0.067 13.3 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 DnaJ domain TPR_7 PF13176.6 KXS13944.1 - 0.074 13.1 0.2 6.7 7.0 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 KXS13944.1 - 0.1 12.3 0.0 0.95 9.2 0.1 2.2 2 0 0 2 2 2 0 TPR repeat TPR_17 PF13431.6 KXS13944.1 - 0.13 12.7 0.4 1.2 9.6 0.1 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KXS13944.1 - 0.22 12.4 1.5 14 6.9 0.1 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 KXS13944.1 - 0.69 10.7 2.1 5.6 7.8 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Adaptin_N PF01602.20 KXS13945.1 - 9.7e-118 394.0 9.9 1.3e-117 393.6 9.9 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 KXS13945.1 - 7.2e-57 191.8 0.1 1.9e-56 190.4 0.0 1.8 2 0 0 2 2 2 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 KXS13945.1 - 1.3e-36 125.3 0.0 3.4e-36 123.9 0.0 1.8 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 KXS13945.1 - 5.3e-19 68.4 5.8 4.6e-09 36.6 0.1 5.6 3 2 2 5 5 5 3 HEAT repeats Cnd1 PF12717.7 KXS13945.1 - 4e-16 59.5 9.6 5.2e-07 29.8 0.2 4.3 4 0 0 4 4 4 3 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KXS13945.1 - 2.7e-05 24.0 13.1 11 6.6 0.3 7.4 7 0 0 7 7 7 2 HEAT repeat HEAT_EZ PF13513.6 KXS13945.1 - 0.0003 21.2 8.4 0.0075 16.8 1.4 4.3 4 0 0 4 4 4 1 HEAT-like repeat HEAT_PBS PF03130.16 KXS13945.1 - 0.0082 16.7 3.4 9.7 7.2 0.1 5.0 4 0 0 4 4 4 1 PBS lyase HEAT-like repeat Arm PF00514.23 KXS13945.1 - 0.079 13.0 1.2 12 6.1 0.0 4.4 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat KdgT PF03812.13 KXS13945.1 - 0.13 11.5 1.1 5 6.3 0.4 2.3 2 0 0 2 2 2 0 2-keto-3-deoxygluconate permease F1F0-ATPsyn_F PF10791.9 KXS13946.1 - 5.6e-09 36.3 0.1 6e-09 36.3 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi tRNA_int_endo PF01974.17 KXS13947.1 - 1.9e-16 59.9 0.1 5.8e-16 58.3 0.1 1.8 2 0 0 2 2 2 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.14 KXS13947.1 - 7.2e-06 25.6 0.0 1.8e-05 24.3 0.0 1.6 1 1 0 1 1 1 1 tRNA intron endonuclease, N-terminal domain Glyco_hydro_63 PF03200.16 KXS13948.1 - 3.5e-163 543.9 1.5 1.2e-101 340.9 0.0 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 KXS13948.1 - 9.2e-55 186.2 0.0 1.5e-54 185.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 63 N-terminal domain Trehalase PF01204.18 KXS13948.1 - 0.00047 19.1 0.0 0.00074 18.5 0.0 1.2 1 0 0 1 1 1 1 Trehalase Bac_rhamnosid6H PF17389.2 KXS13948.1 - 0.0012 18.2 0.0 0.0048 16.2 0.0 1.9 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain WD40 PF00400.32 KXS13951.1 - 3.5e-33 113.1 12.2 0.0063 17.3 0.0 11.7 12 0 0 12 12 12 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXS13951.1 - 2.3e-14 53.5 0.1 0.05 13.9 0.0 6.0 5 2 0 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KXS13951.1 - 2.1e-10 40.4 0.3 2.6e-06 27.0 0.0 3.8 4 1 0 4 4 4 2 WD40-like domain PQQ_2 PF13360.6 KXS13951.1 - 7.7e-08 32.2 0.7 0.0084 15.7 0.0 4.5 1 1 3 4 4 4 3 PQQ-like domain PQQ_3 PF13570.6 KXS13951.1 - 1.3e-06 28.7 5.0 1.3 9.6 0.0 6.4 6 1 0 6 6 6 2 PQQ-like domain BBS2_Mid PF14783.6 KXS13951.1 - 0.0018 18.3 0.2 11 6.1 0.0 4.2 3 1 0 4 4 4 1 Ciliary BBSome complex subunit 2, middle region DUF2169 PF09937.9 KXS13951.1 - 0.039 13.4 0.0 0.11 11.9 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2169) SBBP PF06739.11 KXS13951.1 - 0.052 13.5 0.1 19 5.4 0.0 3.2 3 0 0 3 3 3 0 Beta-propeller repeat Rtt106 PF08512.12 KXS13952.1 - 9.2e-21 74.1 0.1 3.5e-20 72.2 0.0 1.9 2 0 0 2 2 2 1 Histone chaperone Rttp106-like PH_18 PF18469.1 KXS13952.1 - 0.00073 19.5 0.0 0.0018 18.2 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain Tox-REase-3 PF15647.6 KXS13952.1 - 0.32 11.3 1.1 0.63 10.3 0.3 1.9 2 0 0 2 2 2 0 Restriction endonuclease fold toxin 3 RRM_1 PF00076.22 KXS13953.1 - 0.0019 18.0 0.1 0.0065 16.3 0.1 1.9 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) adh_short_C2 PF13561.6 KXS13954.1 - 3.8e-10 39.7 0.0 4.2e-10 39.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase zf-C3HC4_3 PF13920.6 KXS13956.1 - 1.9e-15 56.4 8.9 2.7e-15 55.9 8.9 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KXS13956.1 - 2.5e-09 36.8 7.4 3.9e-09 36.2 7.4 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KXS13956.1 - 1.7e-06 27.9 10.1 2.4e-06 27.4 10.1 1.2 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KXS13956.1 - 5.9e-05 22.9 9.5 9e-05 22.3 9.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXS13956.1 - 8e-05 22.9 10.3 0.00013 22.2 10.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KXS13956.1 - 0.0043 16.9 10.9 0.007 16.2 10.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-P11 PF03854.14 KXS13956.1 - 0.061 13.0 5.5 0.13 12.0 5.5 1.6 1 0 0 1 1 1 0 P-11 zinc finger FdhE PF04216.12 KXS13956.1 - 0.53 10.1 4.9 0.85 9.4 4.9 1.2 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation zf-C3HC4_4 PF15227.6 KXS13956.1 - 0.69 10.1 5.0 13 6.0 5.5 2.2 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING NUC153 PF08159.12 KXS13957.1 - 1.9e-10 40.3 2.3 9e-10 38.2 1.0 2.3 2 0 0 2 2 2 1 NUC153 domain WD40 PF00400.32 KXS13957.1 - 0.00044 21.0 0.3 2.5 9.1 0.5 3.5 3 0 0 3 3 3 2 WD domain, G-beta repeat NUP50 PF08911.11 KXS13957.1 - 0.028 15.1 4.7 0.088 13.5 4.7 1.9 1 0 0 1 1 1 0 NUP50 (Nucleoporin 50 kDa) ANAPC4_WD40 PF12894.7 KXS13957.1 - 0.047 14.0 0.0 0.12 12.6 0.0 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain DUF4746 PF15928.5 KXS13957.1 - 0.57 9.6 5.9 1.2 8.5 5.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Nop14 PF04147.12 KXS13957.1 - 4.5 5.4 13.8 6.7 4.8 13.8 1.2 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 KXS13957.1 - 8.5 4.3 7.1 13 3.7 7.1 1.2 1 0 0 1 1 1 0 DNA polymerase phi Mito_fiss_reg PF05308.11 KXS13958.1 - 9.2 6.3 10.2 2.2 8.3 1.6 2.1 2 0 0 2 2 2 0 Mitochondrial fission regulator Mito_fiss_reg PF05308.11 KXS13959.1 - 1.3 9.0 3.2 2 8.5 3.2 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 KXS13959.1 - 6.8 6.1 7.1 9.6 5.6 7.1 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Pribosyltran_N PF13793.6 KXS13960.1 - 6.5e-45 151.8 0.3 2e-43 147.0 0.1 2.3 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 KXS13960.1 - 2.1e-44 151.7 1.4 1.3e-39 136.1 0.5 2.6 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 KXS13960.1 - 2e-15 56.6 1.4 4.1e-14 52.4 0.4 2.3 2 0 0 2 2 2 1 Phosphoribosyl transferase domain Glyco_hydro_88 PF07470.13 KXS13962.1 - 2.9e-32 112.1 0.0 4e-32 111.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 YHYH PF14240.6 KXS13962.1 - 0.0015 18.5 0.4 1.4 8.9 0.1 2.3 2 0 0 2 2 2 2 YHYH protein NAD_binding_5 PF07994.12 KXS13964.1 - 5.8e-138 459.7 0.0 6.8e-138 459.4 0.0 1.0 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 KXS13964.1 - 2.5e-44 150.0 0.0 4.3e-44 149.2 0.0 1.4 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase SelK_SelG PF10961.8 KXS13965.1 - 0.032 14.9 0.2 0.034 14.8 0.2 1.1 1 0 0 1 1 1 0 Selenoprotein SelK_SelG Surp PF01805.20 KXS13967.1 - 5.2e-22 77.6 0.2 4.1e-10 39.5 0.1 2.4 2 0 0 2 2 2 2 Surp module DRY_EERY PF09750.9 KXS13967.1 - 1.5e-13 51.2 0.4 6.6e-13 49.1 0.4 2.1 1 1 0 1 1 1 1 Alternative splicing regulator Caldesmon PF02029.15 KXS13967.1 - 1.7 7.3 12.5 0.019 13.7 2.6 2.0 2 0 0 2 2 2 0 Caldesmon F-box-like PF12937.7 KXS13969.1 - 1.1e-06 28.4 1.2 1.1e-06 28.4 1.2 2.2 2 1 0 2 2 2 1 F-box-like F-box PF00646.33 KXS13969.1 - 1.1e-05 25.1 1.6 2.4e-05 24.1 0.4 2.1 2 0 0 2 2 2 1 F-box domain F-box_4 PF15966.5 KXS13969.1 - 0.0013 18.6 0.1 0.004 17.0 0.0 1.8 2 0 0 2 2 2 1 F-box DUF410 PF04190.13 KXS13971.1 - 3.6e-50 171.1 0.0 5.7e-50 170.5 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF410) TPR_20 PF14561.6 KXS13971.1 - 0.037 14.3 0.0 0.07 13.5 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat Vps54_N PF10475.9 KXS13971.1 - 0.094 12.0 0.2 0.15 11.3 0.2 1.2 1 0 0 1 1 1 0 Vacuolar-sorting protein 54, of GARP complex TetR_C_27 PF17935.1 KXS13973.1 - 0.05 13.7 0.1 1.1 9.3 0.0 2.1 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Glyco_trans_2_3 PF13632.6 KXS13977.1 - 1.5e-14 54.4 1.0 2e-14 54.0 0.6 1.6 1 1 0 1 1 1 1 Glycosyl transferase family group 2 MFS_1 PF07690.16 KXS13978.1 - 6.1e-27 94.5 33.0 7.7e-27 94.1 33.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily ECH_1 PF00378.20 KXS13979.1 - 1.8e-15 57.0 0.0 2.8e-14 53.0 0.0 2.3 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXS13979.1 - 2.1e-09 37.3 0.1 6.7e-06 25.8 0.2 2.1 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase MOSC PF03473.17 KXS13982.1 - 1.5e-15 57.3 0.0 2.2e-15 56.9 0.0 1.2 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 KXS13982.1 - 7e-14 51.7 0.1 3.3e-08 33.4 0.0 3.0 2 2 1 4 4 4 2 MOSC N-terminal beta barrel domain Peptidase_S8 PF00082.22 KXS13983.1 - 6.9e-65 219.2 2.0 1e-63 215.4 0.6 2.3 2 0 0 2 2 2 1 Subtilase family TPPII PF12580.8 KXS13983.1 - 1.4e-49 168.2 0.0 3.1e-49 167.1 0.0 1.5 1 0 0 1 1 1 1 Tripeptidyl peptidase II DUF885 PF05960.11 KXS13983.1 - 0.043 13.5 2.5 0.059 13.0 1.6 1.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF885) Spectrin_like PF18373.1 KXS13983.1 - 0.22 11.6 0.0 0.5 10.5 0.0 1.5 1 0 0 1 1 1 0 Spectrin like domain PFK PF00365.20 KXS13984.1 - 3.4e-25 88.9 0.1 4.9e-13 49.1 0.0 3.1 1 1 1 2 2 2 2 Phosphofructokinase PFK PF00365.20 KXS13985.1 - 1.1e-35 123.4 0.0 1.1e-35 123.3 0.0 1.0 1 0 0 1 1 1 1 Phosphofructokinase NAD_kinase PF01513.21 KXS13985.1 - 0.073 12.2 0.1 0.094 11.9 0.1 1.2 1 0 0 1 1 1 0 ATP-NAD kinase DAGK_cat PF00781.24 KXS13985.1 - 0.14 11.8 0.4 0.25 11.0 0.1 1.5 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain F-box-like PF12937.7 KXS13987.1 - 7.5e-12 45.0 2.0 7.5e-12 45.0 2.0 1.7 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KXS13987.1 - 2.4e-07 30.5 1.9 5.4e-07 29.3 1.9 1.6 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KXS13987.1 - 0.016 15.1 0.1 0.098 12.5 0.0 2.1 2 0 0 2 2 2 0 F-box LRR_1 PF00560.33 KXS13987.1 - 0.27 11.9 2.6 12 6.9 0.2 3.1 2 0 0 2 2 2 0 Leucine Rich Repeat SHNi-TPR PF10516.9 KXS13988.1 - 2.2e-07 30.2 0.1 8.2e-07 28.4 0.0 2.0 2 0 0 2 2 2 1 SHNi-TPR TPR_12 PF13424.6 KXS13988.1 - 7e-05 23.0 0.2 0.0015 18.7 0.0 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 KXS13988.1 - 0.0012 18.8 2.3 1.5 9.2 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KXS13988.1 - 0.0061 17.2 3.4 4.6 8.0 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat NOA36 PF06524.12 KXS13988.1 - 0.54 9.5 5.4 1 8.6 5.4 1.4 1 0 0 1 1 1 0 NOA36 protein TPR_14 PF13428.6 KXS13988.1 - 2.7 9.1 4.7 20 6.3 0.3 4.1 4 1 0 4 4 4 0 Tetratricopeptide repeat RNA_pol_3_Rpc31 PF11705.8 KXS13988.1 - 8.3 6.6 12.2 0.99 9.6 5.3 2.3 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 DIOX_N PF14226.6 KXS13989.1 - 3.8e-19 69.6 0.0 7.5e-19 68.6 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KXS13989.1 - 6e-16 58.8 0.0 1.5e-15 57.5 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Rootletin PF15035.6 KXS13990.1 - 5.1 7.1 10.5 8.9 6.3 9.8 1.8 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DUF962 PF06127.11 KXS13991.1 - 4.2e-22 78.0 1.2 1e-21 76.8 1.2 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF962) Ribophorin_II PF05817.14 KXS13991.1 - 0.0023 16.6 0.1 0.0031 16.1 0.1 1.2 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II DUF3561 PF12084.8 KXS13991.1 - 0.059 13.4 5.9 0.11 12.5 5.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3561) Acyl-CoA_dh_1 PF00441.24 KXS13992.1 - 1.1e-35 123.1 0.4 1.7e-35 122.5 0.4 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KXS13992.1 - 7.1e-25 87.9 0.0 1.7e-24 86.7 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KXS13992.1 - 3.5e-20 72.0 0.1 8.3e-20 70.8 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KXS13992.1 - 2.7e-14 53.6 1.3 6.4e-14 52.4 1.3 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain MIF4G_like_2 PF09090.11 KXS13993.1 - 9.3e-38 130.2 0.0 1.9e-37 129.2 0.0 1.5 1 0 0 1 1 1 1 MIF4G like MIF4G_like PF09088.11 KXS13993.1 - 8.7e-27 94.1 0.2 2e-26 93.0 0.2 1.7 1 0 0 1 1 1 1 MIF4G like MIF4G PF02854.19 KXS13993.1 - 8.1e-07 28.9 0.0 2.1e-06 27.6 0.0 1.6 2 0 0 2 2 2 1 MIF4G domain DEAD PF00270.29 KXS13996.1 - 1.1e-39 136.0 0.0 2e-39 135.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXS13996.1 - 1.6e-29 102.5 0.0 3.2e-27 95.1 0.1 2.8 2 1 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXS13996.1 - 1.4e-08 34.9 0.0 2.2e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 KXS13996.1 - 0.00017 21.0 0.0 0.00037 19.9 0.0 1.4 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit UvrD-helicase PF00580.21 KXS13996.1 - 0.077 12.5 0.0 0.16 11.5 0.0 1.7 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain zf-UBR PF02207.20 KXS13997.1 - 9.7e-11 41.7 11.8 9.7e-11 41.7 11.8 2.8 3 1 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) PHD PF00628.29 KXS13997.1 - 0.00026 20.8 12.4 0.00026 20.8 12.4 3.8 3 1 1 4 4 4 1 PHD-finger AIG1 PF04548.16 KXS13999.1 - 5.4e-05 22.6 0.0 0.0029 17.0 0.0 2.3 2 0 0 2 2 2 1 AIG1 family Dynamin_N PF00350.23 KXS13999.1 - 0.00011 22.3 0.0 0.00036 20.6 0.0 1.8 1 1 0 1 1 1 1 Dynamin family ABC_tran PF00005.27 KXS13999.1 - 0.00023 21.7 0.0 0.00071 20.1 0.0 1.6 1 1 0 1 1 1 1 ABC transporter MMR_HSR1 PF01926.23 KXS13999.1 - 0.0013 18.8 0.0 0.003 17.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KXS13999.1 - 0.002 18.5 0.0 0.0038 17.6 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 KXS13999.1 - 0.0055 16.6 0.0 0.049 13.5 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase CRAL_TRIO_2 PF13716.6 KXS13999.1 - 0.019 15.1 0.0 0.036 14.2 0.0 1.4 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain Septin PF00735.18 KXS13999.1 - 0.05 12.9 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 Septin AAA_23 PF13476.6 KXS13999.1 - 0.15 12.6 0.8 0.41 11.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain HMG_box PF00505.19 KXS14000.1 - 3.6e-11 43.3 0.1 3.6e-11 43.3 0.1 2.2 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KXS14000.1 - 0.0004 20.9 0.0 0.0004 20.9 0.0 1.9 2 0 0 2 2 2 1 HMG-box domain DDE_Tnp_4 PF13359.6 KXS14001.1 - 2.4e-13 50.1 0.0 3.1e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Lipase_3 PF01764.25 KXS14003.1 - 4.8e-06 26.5 0.1 0.027 14.3 0.0 3.0 3 0 0 3 3 3 2 Lipase (class 3) MMR_HSR1 PF01926.23 KXS14003.1 - 0.00093 19.3 0.0 0.0025 17.9 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Glyco_hydro_26 PF02156.15 KXS14004.1 - 7.8e-10 38.7 8.2 2.1e-07 30.7 8.2 2.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 26 Methyltransf_31 PF13847.6 KXS14005.1 - 6.6e-33 113.6 0.0 9.8e-33 113.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXS14005.1 - 5.8e-23 81.4 0.0 1.2e-22 80.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXS14005.1 - 3.2e-22 79.0 0.0 6.8e-22 77.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXS14005.1 - 1.6e-19 70.2 0.0 2.4e-18 66.3 0.0 2.1 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 KXS14005.1 - 7.2e-14 52.0 0.0 1.2e-13 51.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXS14005.1 - 1.2e-12 48.4 0.0 1.9e-12 47.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KXS14005.1 - 6.7e-10 39.1 0.0 1.7e-09 37.8 0.0 1.5 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 KXS14005.1 - 2.1e-08 33.9 0.0 4e-08 33.0 0.0 1.4 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KXS14005.1 - 9.3e-05 22.0 0.0 0.0002 20.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 KXS14005.1 - 0.00095 18.5 0.0 0.0015 17.9 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase UPF0020 PF01170.18 KXS14005.1 - 0.0079 15.9 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_32 PF13679.6 KXS14005.1 - 0.013 15.5 6.5 0.11 12.5 6.5 2.2 1 1 0 1 1 1 0 Methyltransferase domain GCD14 PF08704.10 KXS14005.1 - 0.018 14.7 0.0 0.035 13.8 0.0 1.4 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit DOT1 PF08123.13 KXS14005.1 - 0.022 14.3 0.0 0.065 12.8 0.0 1.7 2 0 0 2 2 2 0 Histone methylation protein DOT1 Fibrillarin PF01269.17 KXS14005.1 - 0.041 13.0 0.0 0.092 11.8 0.0 1.5 2 0 0 2 2 2 0 Fibrillarin FtsJ PF01728.19 KXS14005.1 - 0.052 13.7 0.0 0.21 11.7 0.0 1.9 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_8 PF05148.15 KXS14005.1 - 0.12 12.2 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 Hypothetical methyltransferase Methyltransf_4 PF02390.17 KXS14005.1 - 0.13 11.7 0.0 0.53 9.7 0.0 1.9 3 0 0 3 3 3 0 Putative methyltransferase Methyltransf_16 PF10294.9 KXS14005.1 - 0.16 11.7 0.2 0.3 10.8 0.0 1.5 2 0 0 2 2 2 0 Lysine methyltransferase zf-RING_2 PF13639.6 KXS14006.1 - 9.3e-14 51.5 4.9 1.4e-13 50.9 4.9 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KXS14006.1 - 7.2e-11 41.7 5.7 1.1e-10 41.1 5.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXS14006.1 - 9.7e-10 38.2 4.4 1.4e-09 37.6 4.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KXS14006.1 - 7.3e-09 35.8 6.0 1.8e-08 34.5 6.0 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 KXS14006.1 - 2.1e-08 33.8 1.5 4.3e-08 32.8 1.5 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 KXS14006.1 - 8.8e-07 28.8 0.8 8.8e-07 28.8 0.8 2.0 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 KXS14006.1 - 1.1e-06 28.5 3.1 1.6e-06 28.0 3.1 1.2 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 KXS14006.1 - 8.7e-06 25.7 2.1 1.6e-05 24.9 2.1 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 KXS14006.1 - 4.1e-05 23.3 3.6 5.9e-05 22.8 3.6 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KXS14006.1 - 0.00038 20.0 4.0 0.00074 19.1 4.0 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 KXS14006.1 - 0.0012 19.0 3.2 0.0027 17.8 3.2 1.6 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING RINGv PF12906.7 KXS14006.1 - 0.0022 18.1 1.8 0.0052 16.9 1.8 1.7 1 1 0 1 1 1 1 RING-variant domain Prok-RING_4 PF14447.6 KXS14006.1 - 0.0044 16.8 6.2 0.043 13.7 0.7 2.2 1 1 1 2 2 2 2 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 KXS14006.1 - 0.0073 16.1 4.1 0.032 14.0 4.4 1.8 1 1 1 2 2 2 1 RING/Ubox like zinc-binding domain zf-Nse PF11789.8 KXS14006.1 - 0.0083 15.9 2.3 0.014 15.2 2.3 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING-like PF08746.11 KXS14006.1 - 0.025 14.9 2.6 0.049 14.0 2.6 1.5 1 1 0 1 1 1 0 RING-like domain FANCL_C PF11793.8 KXS14006.1 - 0.075 13.2 7.1 0.32 11.2 7.1 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain PHD PF00628.29 KXS14006.1 - 0.11 12.5 3.0 0.2 11.6 3.0 1.5 1 0 0 1 1 1 0 PHD-finger Rad50_zn_hook PF04423.14 KXS14006.1 - 0.18 11.7 0.6 9.6 6.1 0.0 2.2 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-Di19 PF05605.12 KXS14006.1 - 0.23 11.8 6.4 2.2 8.6 6.4 2.1 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C3H2C3 PF17122.5 KXS14006.1 - 7.1 6.8 10.4 1.3 9.1 4.4 2.5 2 1 0 2 2 2 0 Zinc-finger SH3_1 PF00018.28 KXS14007.1 - 0.00053 19.5 0.0 0.0011 18.5 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KXS14007.1 - 0.0075 16.1 0.1 0.036 13.9 0.0 2.2 3 0 0 3 3 3 1 Variant SH3 domain SR-25 PF10500.9 KXS14008.1 - 8.2 6.0 6.2 11 5.6 6.2 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RRM_1 PF00076.22 KXS14009.1 - 4.3e-12 45.7 0.0 6.2e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 KXS14009.1 - 0.13 12.4 0.0 0.32 11.2 0.0 1.7 1 0 0 1 1 1 0 RRM-like domain DRY_EERY PF09750.9 KXS14010.1 - 2.3e-17 63.6 0.0 2.3e-17 63.6 0.0 2.6 3 0 0 3 3 3 1 Alternative splicing regulator DUF501 PF04417.12 KXS14010.1 - 0.35 10.7 2.1 0.45 10.3 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF501) DUF4981 PF16353.5 KXS14013.1 - 0.14 12.6 0.1 0.36 11.3 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function(DUF4981) SnoaL PF07366.12 KXS14014.1 - 1.1e-07 31.7 0.0 1.9e-07 30.9 0.0 1.5 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 KXS14014.1 - 1.2e-06 29.1 0.0 1.9e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like domain Chromo PF00385.24 KXS14015.1 - 2.3e-16 59.5 7.6 6.3e-16 58.0 0.3 3.0 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.6 KXS14015.1 - 0.025 14.7 6.3 1.2 9.4 0.6 2.4 2 0 0 2 2 2 0 Polycomb-like MTF2 factor 2 Tudor-knot PF11717.8 KXS14015.1 - 0.11 12.4 0.0 0.43 10.5 0.0 1.9 2 0 0 2 2 2 0 RNA binding activity-knot of a chromodomain Tudor-knot PF11717.8 KXS14017.1 - 0.0017 18.2 2.7 0.0019 18.0 2.7 1.4 1 1 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.24 KXS14017.1 - 0.0021 17.9 1.1 0.0038 17.1 1.1 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain SecE PF00584.20 KXS14018.1 - 1.9e-14 53.3 0.0 2.1e-14 53.2 0.0 1.0 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex COesterase PF00135.28 KXS14019.1 - 1.1e-10 41.1 0.0 1e-09 37.8 0.0 2.1 1 1 1 2 2 2 1 Carboxylesterase family UNC-79 PF14776.6 KXS14019.1 - 0.16 10.7 0.2 0.23 10.2 0.2 1.1 1 0 0 1 1 1 0 Cation-channel complex subunit UNC-79 LRR_4 PF12799.7 KXS14020.1 - 1.8e-10 40.9 15.9 0.00017 21.9 0.5 3.4 1 1 4 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXS14020.1 - 0.00043 20.0 12.8 0.022 14.5 2.2 2.9 1 1 2 3 3 3 3 Leucine rich repeat LRR_1 PF00560.33 KXS14020.1 - 0.00065 19.9 5.7 5.1 8.0 0.0 5.2 5 1 0 5 5 5 2 Leucine Rich Repeat Herpes_gE PF02480.16 KXS14020.1 - 0.017 13.9 0.0 0.022 13.5 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E LRR_6 PF13516.6 KXS14020.1 - 0.035 14.2 11.4 0.78 9.9 0.2 4.6 5 0 0 5 5 5 0 Leucine Rich repeat TrbC PF04956.13 KXS14020.1 - 0.096 12.9 3.7 5.3 7.3 0.1 2.4 2 0 0 2 2 2 0 TrbC/VIRB2 family Adeno_E3_CR2 PF02439.15 KXS14020.1 - 0.3 10.9 6.7 0.6 9.9 6.7 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Syndecan PF01034.20 KXS14020.1 - 0.92 9.5 2.4 2 8.4 2.4 1.5 1 0 0 1 1 1 0 Syndecan domain DUF2970 PF11174.8 KXS14020.1 - 5.8 6.8 7.4 0.28 11.1 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2970) LRR_4 PF12799.7 KXS14021.1 - 3e-12 46.5 13.7 5e-05 23.6 5.8 3.5 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXS14021.1 - 3.7e-05 23.4 22.2 0.00025 20.7 4.6 3.7 2 1 3 5 5 5 4 Leucine rich repeat LRR_1 PF00560.33 KXS14021.1 - 0.0014 18.9 14.7 3.8 8.4 0.1 5.8 3 1 1 4 4 4 2 Leucine Rich Repeat Protocadherin PF08374.11 KXS14021.1 - 0.18 11.8 0.0 0.25 11.3 0.0 1.2 1 0 0 1 1 1 0 Protocadherin LRR_6 PF13516.6 KXS14021.1 - 0.25 11.5 8.5 3.7 7.9 0.4 4.2 4 0 0 4 4 4 0 Leucine Rich repeat HIT PF01230.23 KXS14022.1 - 6.3e-19 68.5 0.2 9.5e-19 68.0 0.2 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KXS14022.1 - 2.1e-09 37.8 0.0 3.1e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 KXS14022.1 - 0.00014 21.7 0.3 0.0002 21.2 0.3 1.4 1 1 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 DUF4158 PF13700.6 KXS14023.1 - 0.053 13.3 0.1 5.4 6.8 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4158) Cyanate_lyase PF02560.14 KXS14026.1 - 1e-20 73.3 0.1 1.4e-20 72.9 0.1 1.2 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain HTH_31 PF13560.6 KXS14026.1 - 0.032 14.6 0.0 0.044 14.1 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain PKS_DE PF18369.1 KXS14026.1 - 0.058 14.0 0.1 0.14 12.7 0.1 1.5 1 0 0 1 1 1 0 Polyketide synthase dimerisation element domain AI-2E_transport PF01594.16 KXS14027.1 - 0.027 13.6 0.8 0.034 13.3 0.8 1.0 1 0 0 1 1 1 0 AI-2E family transporter Lectin_N PF03954.14 KXS14027.1 - 0.073 12.8 0.1 0.085 12.6 0.1 1.1 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain SP_C-Propep PF08999.10 KXS14027.1 - 0.14 12.0 1.5 0.21 11.4 1.4 1.6 1 1 0 1 1 1 0 Surfactant protein C, N terminal propeptide Homoserine_dh PF00742.19 KXS14029.1 - 4.6e-49 166.7 0.0 5.9e-49 166.3 0.0 1.1 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 KXS14029.1 - 4.6e-21 75.6 0.0 6.7e-21 75.1 0.0 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Glycos_transf_2 PF00535.26 KXS14030.1 - 2.5e-34 118.5 0.0 3e-34 118.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KXS14030.1 - 3.8e-16 59.7 0.0 4.7e-16 59.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 KXS14030.1 - 0.00051 19.6 0.0 0.00067 19.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KXS14030.1 - 0.00075 19.0 0.0 0.0011 18.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_4 PF13704.6 KXS14030.1 - 0.0088 16.5 0.0 0.022 15.2 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferase family 2 NTPase_I-T PF01931.18 KXS14032.1 - 2e-53 180.5 0.0 2.3e-53 180.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF84 Peptidase_C14 PF00656.22 KXS14033.1 - 4e-51 174.4 0.1 5.5e-51 173.9 0.1 1.1 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.6 KXS14033.1 - 2.3 8.1 5.8 0.64 10.0 0.1 2.8 3 1 0 3 3 3 0 Raptor N-terminal CASPase like domain DUF4201 PF13870.6 KXS14034.1 - 0.024 14.4 0.2 0.038 13.7 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) MFS_1 PF07690.16 KXS14035.1 - 3.1e-20 72.4 55.6 3.2e-17 62.5 21.3 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily Abhydrolase_4 PF08386.10 KXS14037.1 - 1.1e-10 41.5 0.0 2.6e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.20 KXS14037.1 - 2.4e-07 30.7 0.0 2.2e-05 24.2 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Sel1 PF08238.12 KXS14040.1 - 1.5e-23 82.7 10.7 1.5e-10 41.4 0.1 4.8 4 1 1 5 5 5 4 Sel1 repeat TPR_1 PF00515.28 KXS14040.1 - 0.054 13.3 5.4 9 6.3 0.1 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.6 KXS14040.1 - 0.06 13.0 11.0 15 5.3 0.2 5.3 4 1 0 5 5 5 0 TPR repeat TPR_2 PF07719.17 KXS14040.1 - 0.2 11.9 4.7 24 5.4 0.0 4.4 4 1 1 5 5 5 0 Tetratricopeptide repeat Pkinase_Tyr PF07714.17 KXS14041.1 - 1.5e-07 30.9 0.0 2.5e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXS14041.1 - 0.067 12.5 0.0 0.088 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain MFS_1 PF07690.16 KXS14042.1 - 1.2e-17 63.9 34.1 1.2e-17 63.9 34.1 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXS14042.1 - 2.6e-06 26.6 16.2 0.004 16.1 9.3 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.6 KXS14042.1 - 0.0028 16.3 26.3 0.0068 15.0 15.2 2.7 2 1 0 2 2 2 2 MFS/sugar transport protein Aldo_ket_red PF00248.21 KXS14043.1 - 6.2e-67 225.9 0.0 7e-67 225.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family SH3_9 PF14604.6 KXS14046.1 - 3.7e-06 26.7 0.0 1.3e-05 25.0 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 KXS14046.1 - 3.8e-05 23.2 0.0 6.7e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SHOCT PF09851.9 KXS14046.1 - 0.026 14.3 0.2 0.043 13.6 0.2 1.3 1 0 0 1 1 1 0 Short C-terminal domain Ring_hydroxyl_A PF00848.19 KXS14047.1 - 8.4e-28 97.8 0.3 2e-27 96.6 0.3 1.5 1 1 0 1 1 1 1 Ring hydroxylating alpha subunit (catalytic domain) Endonuclease_5 PF04493.14 KXS14048.1 - 2.4e-55 187.3 0.0 1.1e-54 185.1 0.0 2.0 1 1 0 1 1 1 1 Endonuclease V UvrC_HhH_N PF08459.11 KXS14048.1 - 0.16 11.9 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 UvrC Helix-hairpin-helix N-terminal DUF3682 PF12446.8 KXS14048.1 - 3.2 8.3 7.4 0.43 11.0 2.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3682) PLDc_2 PF13091.6 KXS14050.1 - 4.8e-49 165.7 0.0 2.1e-23 82.7 0.0 2.6 2 1 0 2 2 2 2 PLD-like domain FAM83 PF07894.12 KXS14050.1 - 4.8e-12 46.0 0.5 0.0014 18.3 0.0 3.8 4 0 0 4 4 4 3 FAM83 A-H PLDc PF00614.22 KXS14050.1 - 5.2e-05 23.2 0.4 0.61 10.4 0.2 3.2 3 0 0 3 3 3 2 Phospholipase D Active site motif Regulator_TrmB PF11495.8 KXS14050.1 - 0.11 11.6 0.0 2.9 7.0 0.0 2.2 2 0 0 2 2 2 0 Archaeal transcriptional regulator TrmB NYN PF01936.18 KXS14050.1 - 0.16 12.4 0.1 0.49 10.9 0.0 1.8 2 0 0 2 2 2 0 NYN domain 120_Rick_ant PF12574.8 KXS14050.1 - 0.18 11.0 0.0 0.29 10.3 0.0 1.2 1 0 0 1 1 1 0 120 KDa Rickettsia surface antigen YabA PF06156.13 KXS14051.1 - 0.01 16.4 0.1 0.013 16.1 0.1 1.2 1 0 0 1 1 1 0 Initiation control protein YabA CENP-H PF05837.12 KXS14051.1 - 0.053 13.9 0.6 0.071 13.5 0.6 1.2 1 0 0 1 1 1 0 Centromere protein H (CENP-H) adh_short PF00106.25 KXS14052.1 - 1.6e-06 27.7 2.1 0.00013 21.5 0.1 2.3 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXS14052.1 - 5.8e-06 26.0 3.6 0.0087 15.6 0.2 2.8 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase YjeF_N PF03853.15 KXS14052.1 - 0.0077 16.1 0.1 0.013 15.4 0.1 1.3 1 0 0 1 1 1 1 YjeF-related protein N-terminus Glyoxalase PF00903.25 KXS14053.1 - 3.9e-09 36.8 0.0 1.1e-08 35.3 0.0 1.7 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glucokinase PF02685.16 KXS14053.1 - 0.18 10.8 0.0 0.21 10.5 0.0 1.1 1 0 0 1 1 1 0 Glucokinase DUF726 PF05277.12 KXS14054.1 - 1.4e-79 267.5 0.0 1.9e-79 267.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Say1_Mug180 PF10340.9 KXS14054.1 - 0.046 12.6 0.4 0.5 9.2 0.4 2.0 1 1 0 1 1 1 0 Steryl acetyl hydrolase LCAT PF02450.15 KXS14054.1 - 0.13 11.4 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase PNP_UDP_1 PF01048.20 KXS14057.1 - 1.5e-20 73.5 0.1 1.7e-20 73.3 0.1 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily GLTP PF08718.11 KXS14061.1 - 2.1e-41 141.6 0.0 2.5e-41 141.4 0.0 1.1 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) zf-C2H2 PF00096.26 KXS14062.1 - 1.1e-09 38.2 7.6 0.0002 21.6 0.9 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KXS14062.1 - 6.4e-09 35.8 1.1 2e-07 31.1 0.1 2.7 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KXS14062.1 - 2.8e-07 30.8 7.2 0.0042 17.8 0.6 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger DZR PF12773.7 KXS14062.1 - 0.029 14.4 0.2 0.056 13.5 0.2 1.4 1 0 0 1 1 1 0 Double zinc ribbon zf-Di19 PF05605.12 KXS14062.1 - 0.038 14.3 1.8 2.2 8.6 0.0 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 KXS14062.1 - 0.048 13.7 2.8 6.8 6.8 0.5 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KXS14062.1 - 0.048 13.4 0.2 0.14 11.9 0.2 1.9 1 0 0 1 1 1 0 C2H2-type zinc-finger domain zf-met PF12874.7 KXS14062.1 - 0.068 13.6 0.1 0.068 13.6 0.1 2.1 2 0 0 2 2 2 0 Zinc-finger of C2H2 type ADK_lid PF05191.14 KXS14062.1 - 0.072 13.1 1.7 4.4 7.4 0.6 3.1 3 0 0 3 3 3 0 Adenylate kinase, active site lid zf-C2H2_11 PF16622.5 KXS14062.1 - 0.2 11.4 5.3 1.4 8.8 0.5 2.4 2 0 0 2 2 2 0 zinc-finger C2H2-type GAGA PF09237.11 KXS14062.1 - 0.39 10.6 4.1 0.16 11.8 0.8 2.0 1 1 1 2 2 2 0 GAGA factor Zn-ribbon_8 PF09723.10 KXS14062.1 - 0.47 10.6 2.8 0.87 9.8 0.5 2.1 1 1 1 2 2 2 0 Zinc ribbon domain DUF1610 PF07754.11 KXS14062.1 - 0.69 9.9 2.8 1.4 9.0 2.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1610) zf-C2H2_2 PF12756.7 KXS14062.1 - 0.74 10.2 3.1 18 5.7 0.1 2.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf_UBZ PF18439.1 KXS14062.1 - 1.7 8.3 3.8 4.1 7.1 0.0 2.5 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger DUF4200 PF13863.6 KXS14063.1 - 4.7e-27 94.7 7.5 4.7e-27 94.7 7.5 3.7 4 0 0 4 4 4 2 Domain of unknown function (DUF4200) Transformer PF06495.11 KXS14063.1 - 0.0034 17.5 10.5 0.011 15.8 10.5 1.9 1 0 0 1 1 1 1 Fruit fly transformer protein DUF1993 PF09351.10 KXS14063.1 - 1.1 9.4 3.1 2.3 8.3 0.1 2.8 2 2 1 3 3 3 0 Domain of unknown function (DUF1993) Spem1 PF15670.5 KXS14063.1 - 4.9 6.7 6.3 1.4 8.4 2.6 1.9 2 0 0 2 2 2 0 Spermatid maturation protein 1 Stathmin PF00836.19 KXS14064.1 - 0.085 12.8 19.4 0.052 13.5 9.3 2.8 2 1 0 2 2 2 0 Stathmin family Zn_clus PF00172.18 KXS14065.1 - 0.001 19.1 12.1 0.0017 18.4 12.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Oxidored-like PF09791.9 KXS14068.1 - 6.6e-12 44.9 2.0 1.3e-11 44.0 2.0 1.4 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal DUF5522 PF17653.1 KXS14068.1 - 0.014 15.3 4.5 0.028 14.4 4.5 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5522) ADH_zinc_N PF00107.26 KXS14069.1 - 8.3e-11 42.0 0.9 1.6e-10 41.0 0.9 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXS14069.1 - 1.8e-08 35.5 0.0 3.2e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXS14069.1 - 0.00028 20.7 0.0 0.00051 19.9 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Glyco_trans_4_4 PF13579.6 KXS14069.1 - 0.0074 16.7 1.0 0.14 12.6 0.1 2.2 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Pantoate_transf PF02548.15 KXS14069.1 - 0.009 15.4 0.0 0.019 14.4 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase Prp19 PF08606.11 KXS14070.1 - 9.3e-30 102.4 2.4 2e-29 101.3 2.4 1.6 1 0 0 1 1 1 1 Prp19/Pso4-like WD40 PF00400.32 KXS14070.1 - 4.3e-07 30.5 12.3 0.065 14.1 0.1 5.9 6 1 0 6 6 6 3 WD domain, G-beta repeat Cytochrom_D1 PF02239.16 KXS14070.1 - 0.0012 17.4 0.2 0.0036 15.9 0.1 1.7 1 1 1 2 2 2 1 Cytochrome D1 heme domain zf-Nse PF11789.8 KXS14070.1 - 0.028 14.2 0.0 0.048 13.5 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit HPS3_N PF14761.6 KXS14070.1 - 0.099 12.2 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Hermansky-Pudlak syndrome 3 TMF_TATA_bd PF12325.8 KXS14070.1 - 0.1 12.8 0.7 0.24 11.6 0.7 1.6 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DUF4446 PF14584.6 KXS14073.1 - 0.02 14.9 0.1 0.032 14.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) CitMHS_2 PF16980.5 KXS14076.1 - 2.1e-36 125.6 6.4 3.8e-32 111.5 0.4 3.0 3 0 0 3 3 3 3 Putative citrate transport Kelch_5 PF13854.6 KXS14077.1 - 2.1e-19 69.1 0.0 0.00072 19.5 0.0 5.8 5 0 0 5 5 5 5 Kelch motif Kelch_3 PF13415.6 KXS14077.1 - 2.2e-14 53.3 3.8 8.4e-05 22.8 0.0 5.3 5 1 0 5 5 5 4 Galactose oxidase, central domain Kelch_1 PF01344.25 KXS14077.1 - 5.7e-13 48.2 4.7 0.043 13.4 0.0 5.7 5 1 0 5 5 5 4 Kelch motif Kelch_4 PF13418.6 KXS14077.1 - 1.3e-11 44.3 9.2 0.00062 19.7 0.0 5.8 5 1 0 5 5 5 3 Galactose oxidase, central domain Kelch_6 PF13964.6 KXS14077.1 - 3.4e-11 43.0 0.6 0.093 13.1 0.0 5.8 5 1 0 5 5 5 2 Kelch motif Kelch_2 PF07646.15 KXS14077.1 - 1.6e-05 24.6 4.3 0.085 12.9 0.5 5.1 5 1 0 5 5 5 2 Kelch motif DUF5320 PF17253.2 KXS14077.1 - 0.28 12.3 34.2 0.037 15.1 4.5 4.4 3 1 1 4 4 4 0 Family of unknown function (DUF5320) PetM PF08041.11 KXS14078.1 - 0.013 15.1 1.6 0.013 15.1 1.6 1.9 2 1 0 2 2 2 0 PetM family of cytochrome b6f complex subunit 7 TRAM_LAG1_CLN8 PF03798.16 KXS14079.1 - 6e-25 88.1 7.5 6.7e-25 88.0 7.5 1.0 1 0 0 1 1 1 1 TLC domain His_Phos_1 PF00300.22 KXS14080.1 - 1.3e-31 109.8 0.0 1.5e-31 109.6 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF1153 PF06627.11 KXS14080.1 - 0.047 13.8 0.0 0.09 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1153) His_Phos_1 PF00300.22 KXS14081.1 - 2.5e-32 112.1 0.0 2.8e-32 112.0 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF1153 PF06627.11 KXS14081.1 - 0.12 12.5 0.0 0.22 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1153) F-box PF00646.33 KXS14082.1 - 2.9e-05 23.8 0.4 6.5e-05 22.7 0.4 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KXS14082.1 - 6.3e-05 22.8 0.2 0.0001 22.1 0.2 1.3 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 KXS14082.1 - 0.0013 18.6 0.1 0.002 18.0 0.1 1.3 1 0 0 1 1 1 1 F-box Stomagen PF16851.5 KXS14082.1 - 0.11 12.6 0.2 0.22 11.6 0.2 1.5 1 0 0 1 1 1 0 Stomagen adh_short PF00106.25 KXS14083.1 - 2e-31 109.0 0.0 3.6e-31 108.2 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXS14083.1 - 1e-20 74.3 0.1 2.8e-20 72.9 0.1 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXS14083.1 - 1.3e-05 25.2 0.4 0.00018 21.5 0.4 2.3 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KXS14083.1 - 0.0073 15.8 0.1 0.023 14.1 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family TPMT PF05724.11 KXS14083.1 - 0.074 12.7 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) DUF3772 PF12607.8 KXS14084.1 - 0.28 10.9 1.5 0.42 10.4 1.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3772) DUF4602 PF15375.6 KXS14085.1 - 0.00039 20.7 0.1 0.00039 20.7 0.1 2.2 3 0 0 3 3 3 1 Domain of unknown function (DUF4602) DNA_pol_phi PF04931.13 KXS14085.1 - 5.3 5.0 11.7 6.9 4.6 11.7 1.2 1 0 0 1 1 1 0 DNA polymerase phi 4HBT_3 PF13622.6 KXS14086.1 - 1.2e-19 71.6 7.4 5e-18 66.3 5.1 2.2 2 0 0 2 2 2 2 Thioesterase-like superfamily HBB PF06777.11 KXS14087.1 - 0.12 12.1 0.0 0.13 11.9 0.0 1.1 1 0 0 1 1 1 0 Helical and beta-bridge domain BTB_2 PF02214.22 KXS14088.1 - 2.8e-12 46.8 0.0 4.8e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain LRR_6 PF13516.6 KXS14089.1 - 0.00014 21.7 0.4 16 5.9 0.0 5.5 5 0 0 5 5 5 2 Leucine Rich repeat F-box-like PF12937.7 KXS14089.1 - 0.074 13.0 1.5 0.11 12.4 0.1 2.1 2 0 0 2 2 2 0 F-box-like MFS_1 PF07690.16 KXS14094.1 - 7.7e-26 90.8 55.5 2e-14 53.3 32.6 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Ribosomal_L17 PF01196.19 KXS14095.1 - 1.6e-24 86.6 0.1 7.7e-24 84.4 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein L17 Fez1 PF06818.15 KXS14095.1 - 0.019 15.4 3.7 0.14 12.6 0.9 2.2 2 0 0 2 2 2 0 Fez1 DUF4407 PF14362.6 KXS14095.1 - 0.022 14.1 2.4 0.038 13.3 2.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Prefoldin_2 PF01920.20 KXS14095.1 - 0.13 12.2 4.0 8.6 6.4 0.0 2.7 2 1 0 2 2 2 0 Prefoldin subunit CCDC-167 PF15188.6 KXS14095.1 - 0.21 11.9 6.4 3.5 8.0 4.2 2.3 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 Occludin_ELL PF07303.13 KXS14095.1 - 0.32 11.8 2.3 4.7 8.0 0.0 2.5 2 0 0 2 2 2 0 Occludin homology domain Syntaxin-6_N PF09177.11 KXS14095.1 - 0.64 10.6 5.9 0.71 10.5 2.7 2.5 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Caskin-tail PF16632.5 KXS14095.1 - 0.89 10.0 3.3 14 6.1 0.6 2.5 2 0 0 2 2 2 0 C-terminal region of Caskin SlyX PF04102.12 KXS14095.1 - 5 7.8 9.2 15 6.3 0.0 3.3 3 0 0 3 3 3 0 SlyX F-box-like PF12937.7 KXS14096.1 - 0.00035 20.4 0.0 0.00048 20.0 0.0 1.2 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXS14096.1 - 0.0026 17.6 0.0 0.0041 17.0 0.0 1.3 1 0 0 1 1 1 1 F-box domain MFS_1 PF07690.16 KXS14098.1 - 9.4e-42 143.2 37.7 7.9e-41 140.1 37.6 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXS14098.1 - 9.1e-09 34.7 9.9 9.1e-09 34.7 9.9 2.8 2 1 0 3 3 3 1 Sugar (and other) transporter MFS_1_like PF12832.7 KXS14098.1 - 2.4e-05 23.4 2.5 2.4e-05 23.4 2.5 2.2 1 1 0 2 2 2 1 MFS_1 like family MFS_3 PF05977.13 KXS14098.1 - 2.5e-05 22.9 2.2 2.5e-05 22.9 2.2 2.6 3 0 0 3 3 3 1 Transmembrane secretion effector GFA PF04828.14 KXS14101.1 - 2.3e-17 63.1 0.9 3.6e-17 62.5 0.9 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme GFA PF04828.14 KXS14102.1 - 5.1e-14 52.4 0.4 8e-14 51.7 0.4 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme MFS_1 PF07690.16 KXS14103.1 - 3.7e-32 111.6 63.2 5.8e-24 84.7 43.0 2.6 1 1 2 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.24 KXS14103.1 - 0.00083 18.3 33.8 0.11 11.4 33.7 2.9 1 1 0 1 1 1 1 Sugar (and other) transporter ATG16 PF08614.11 KXS14104.1 - 2.3e-05 24.7 15.4 2.3e-05 24.7 15.4 4.0 1 1 2 4 4 4 1 Autophagy protein 16 (ATG16) Spc7 PF08317.11 KXS14104.1 - 0.00025 20.0 46.0 0.0044 16.0 14.1 3.2 2 1 1 3 3 3 2 Spc7 kinetochore protein Sipho_Gp157 PF05565.11 KXS14104.1 - 0.0012 18.9 1.1 0.0012 18.9 1.1 3.9 3 1 1 4 4 4 1 Siphovirus Gp157 TMF_TATA_bd PF12325.8 KXS14104.1 - 0.0093 16.2 10.1 0.0093 16.2 10.1 5.3 4 3 3 7 7 6 1 TATA element modulatory factor 1 TATA binding Baculo_PEP_C PF04513.12 KXS14104.1 - 0.014 15.4 5.0 0.014 15.4 5.0 4.6 2 1 3 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus BLOC1_2 PF10046.9 KXS14104.1 - 0.093 13.0 28.3 0.15 12.4 0.8 4.7 4 1 2 6 6 6 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fez1 PF06818.15 KXS14104.1 - 0.76 10.2 46.3 55 4.1 5.4 3.8 1 1 1 2 2 1 0 Fez1 APG6_N PF17675.1 KXS14104.1 - 0.88 10.1 53.7 0.89 10.1 9.9 5.2 2 1 4 6 6 6 0 Apg6 coiled-coil region Surfac_D-trimer PF09006.11 KXS14104.1 - 0.89 9.5 3.9 0.96 9.4 0.1 2.7 3 0 0 3 3 3 0 Lung surfactant protein D coiled-coil trimerisation YabA PF06156.13 KXS14104.1 - 1.6 9.4 40.3 0.27 11.9 2.2 5.5 2 1 3 5 5 5 0 Initiation control protein YabA DivIC PF04977.15 KXS14104.1 - 2.2 8.1 33.4 2.1 8.2 0.6 6.6 4 2 3 7 7 7 0 Septum formation initiator DUF4407 PF14362.6 KXS14104.1 - 3.2 7.0 28.6 0.35 10.2 1.4 3.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) HrpB7 PF09486.10 KXS14104.1 - 6.7 7.1 27.0 0.088 13.2 5.5 3.9 2 1 2 4 4 4 0 Bacterial type III secretion protein (HrpB7) bZIP_1 PF00170.21 KXS14104.1 - 7.9 6.7 31.8 0.29 11.3 0.8 5.8 6 1 1 7 7 6 0 bZIP transcription factor MFS_1 PF07690.16 KXS14105.1 - 6.7e-28 97.6 13.9 1.2e-21 77.1 1.8 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXS14105.1 - 0.1 11.4 9.3 0.32 9.8 0.7 2.2 2 0 0 2 2 2 0 Sugar (and other) transporter MFS_1_like PF12832.7 KXS14105.1 - 0.42 9.4 11.1 1.8 7.3 1.0 2.7 2 1 0 2 2 2 0 MFS_1 like family Ribosomal_L10 PF00466.20 KXS14106.1 - 1.1e-21 76.8 0.0 1.5e-21 76.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L10 RL10P_insert PF17777.1 KXS14106.1 - 2.7e-20 72.1 0.0 4.7e-20 71.4 0.0 1.3 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Transglut_core PF01841.19 KXS14106.1 - 0.11 13.0 0.0 0.89 10.0 0.0 2.2 3 0 0 3 3 3 0 Transglutaminase-like superfamily DUF349 PF03993.12 KXS14106.1 - 0.13 12.6 1.1 0.36 11.2 1.1 1.7 1 0 0 1 1 1 0 Domain of Unknown Function (DUF349) Pacs-1 PF10254.9 KXS14106.1 - 0.39 9.6 2.5 0.57 9.1 2.5 1.2 1 0 0 1 1 1 0 PACS-1 cytosolic sorting protein Ank_2 PF12796.7 KXS14107.1 - 4e-47 158.7 10.3 1.7e-11 44.5 0.1 7.0 4 2 2 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXS14107.1 - 5.5e-33 112.9 18.4 0.00065 20.2 0.0 12.6 8 3 6 14 14 14 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXS14107.1 - 3.4e-32 106.8 14.8 0.15 12.7 0.0 14.8 15 0 0 15 15 15 8 Ankyrin repeat Ank PF00023.30 KXS14107.1 - 8.5e-24 82.9 34.5 0.015 15.7 0.2 13.3 14 2 0 14 14 14 8 Ankyrin repeat Ank_5 PF13857.6 KXS14107.1 - 1.3e-18 66.8 26.2 0.00026 21.2 0.3 11.8 6 4 7 13 13 13 7 Ankyrin repeats (many copies) CCDC84 PF14968.6 KXS14107.1 - 0.13 11.8 0.0 9.6 5.7 0.0 2.3 2 0 0 2 2 2 0 Coiled coil protein 84 CoiA PF06054.11 KXS14108.1 - 0.068 12.3 0.6 0.11 11.6 0.6 1.2 1 0 0 1 1 1 0 Competence protein CoiA-like family AMP-binding PF00501.28 KXS14109.1 - 6.2e-83 278.7 0.0 8.1e-83 278.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXS14109.1 - 3.4e-16 60.0 0.6 8.5e-16 58.7 0.4 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Prim-Pol PF09250.11 KXS14110.1 - 9.2e-17 61.8 0.0 1.3e-16 61.3 0.0 1.2 1 0 0 1 1 1 1 Bifunctional DNA primase/polymerase, N-terminal LRR_6 PF13516.6 KXS14113.1 - 2e-19 67.9 19.4 4.2e-05 23.3 0.7 7.1 7 0 0 7 7 7 4 Leucine Rich repeat LRR_4 PF12799.7 KXS14113.1 - 0.00015 22.1 9.8 0.17 12.4 0.0 4.7 2 2 3 5 5 5 3 Leucine Rich repeats (2 copies) SpoU_sub_bind PF08032.12 KXS14113.1 - 0.0039 17.4 4.4 3.3 8.0 0.0 4.6 3 2 2 5 5 5 1 RNA 2'-O ribose methyltransferase substrate binding LRR_8 PF13855.6 KXS14113.1 - 0.0064 16.2 7.9 0.44 10.3 0.1 4.2 2 2 1 3 3 3 2 Leucine rich repeat LRR_1 PF00560.33 KXS14113.1 - 0.066 13.8 0.1 2.1e+02 3.1 0.0 4.8 5 0 0 5 5 5 0 Leucine Rich Repeat HOASN PF14515.6 KXS14113.1 - 0.11 12.9 1.2 19 5.7 0.0 2.6 2 0 0 2 2 2 0 Haem-oxygenase-associated N-terminal helices DUF2390 PF09523.10 KXS14113.1 - 0.26 11.6 2.8 0.83 10.0 2.8 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2390) Pox_VLTF3 PF04947.14 KXS14114.1 - 1.7e-36 125.4 0.1 3.2e-36 124.6 0.1 1.4 1 0 0 1 1 1 1 Poxvirus Late Transcription Factor VLTF3 like TF_Zn_Ribbon PF08271.12 KXS14114.1 - 0.0037 16.8 0.4 0.0084 15.6 0.4 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding DUF2318 PF10080.9 KXS14114.1 - 0.053 13.6 0.1 0.097 12.8 0.1 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) RPA_interact_C PF14768.6 KXS14114.1 - 0.072 13.7 0.7 0.2 12.2 0.2 2.0 2 0 0 2 2 2 0 Replication protein A interacting C-terminal zf-NADH-PPase PF09297.11 KXS14114.1 - 0.092 12.4 0.3 0.4 10.4 0.4 2.0 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain PhyH PF05721.13 KXS14115.1 - 1.7e-07 31.7 0.0 3e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Ceramidase PF05875.12 KXS14116.1 - 6.2e-44 150.4 2.5 7.6e-44 150.1 2.5 1.0 1 0 0 1 1 1 1 Ceramidase DUF2157 PF09925.9 KXS14116.1 - 0.025 14.4 6.2 0.017 14.9 3.4 2.1 1 1 1 2 2 2 0 Predicted membrane protein (DUF2157) Trp_oprn_chp PF09534.10 KXS14116.1 - 0.05 13.4 1.5 0.083 12.7 1.5 1.4 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) CcmD PF04995.14 KXS14116.1 - 1.6 8.9 7.8 4.2 7.5 0.1 3.5 3 0 0 3 3 3 0 Heme exporter protein D (CcmD) LRR_4 PF12799.7 KXS14117.1 - 0.065 13.7 10.0 49 4.5 0.1 6.1 6 1 0 6 6 6 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KXS14117.1 - 0.35 11.0 7.1 9.8 6.5 0.0 5.7 8 0 0 8 8 8 0 Leucine Rich repeat MFS_1 PF07690.16 KXS14119.1 - 5.4e-28 97.9 23.4 6.4e-28 97.7 23.4 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Mon1 PF03164.14 KXS14120.1 - 3.3e-109 365.6 0.0 5.5e-109 364.9 0.0 1.3 1 1 0 1 1 1 1 Trafficking protein Mon1 LRR_4 PF12799.7 KXS14121.1 - 3.9e-06 27.1 4.1 0.0021 18.4 0.1 3.3 2 1 3 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXS14121.1 - 7e-05 22.5 1.5 0.00026 20.7 0.0 2.4 3 0 0 3 3 3 1 Leucine rich repeat LRR_1 PF00560.33 KXS14121.1 - 0.13 12.9 4.1 5.2 8.0 0.0 4.0 4 1 1 5 5 5 0 Leucine Rich Repeat FA_desaturase PF00487.24 KXS14122.1 - 2.6e-12 47.1 23.0 2.6e-12 47.1 23.0 1.9 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.28 KXS14122.1 - 2.3e-11 43.7 0.1 4.1e-11 42.9 0.1 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain EFP_N PF08207.12 KXS14122.1 - 0.16 12.0 0.0 0.37 10.9 0.0 1.6 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain F-box PF00646.33 KXS14123.1 - 0.024 14.5 0.4 0.037 13.9 0.4 1.3 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.7 KXS14123.1 - 0.026 14.4 0.2 0.053 13.4 0.2 1.5 1 0 0 1 1 1 0 F-box-like adh_short_C2 PF13561.6 KXS14124.1 - 3.1e-44 151.3 1.3 3.6e-44 151.1 1.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXS14124.1 - 2.5e-33 115.2 0.3 3.3e-33 114.8 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXS14124.1 - 4.4e-06 26.7 2.1 4.6e-05 23.4 2.1 2.0 1 1 0 1 1 1 1 KR domain YjeF_N PF03853.15 KXS14124.1 - 0.035 14.0 0.1 0.061 13.2 0.1 1.4 1 0 0 1 1 1 0 YjeF-related protein N-terminus NAD_binding_10 PF13460.6 KXS14125.1 - 1.3e-06 28.4 0.0 1.7e-06 28.0 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KXS14125.1 - 0.026 13.7 0.0 0.041 13.1 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein Drc1-Sld2 PF11719.8 KXS14126.1 - 0.063 12.8 0.3 0.074 12.6 0.3 1.0 1 0 0 1 1 1 0 DNA replication and checkpoint protein Pkinase PF00069.25 KXS14127.1 - 6.5e-58 196.2 0.0 8.5e-58 195.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS14127.1 - 4.1e-22 78.7 0.0 5.6e-22 78.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXS14127.1 - 7.8e-06 25.4 0.0 1.1e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KXS14127.1 - 7.9e-06 25.1 0.1 8.6e-06 24.9 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KXS14127.1 - 2.4e-05 23.8 0.7 4.1e-05 23.0 0.7 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXS14127.1 - 0.00013 22.0 6.3 0.0018 18.3 1.4 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXS14127.1 - 0.00035 19.5 0.1 0.00049 19.0 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase Choline_kinase PF01633.20 KXS14127.1 - 0.0015 18.2 0.6 0.0021 17.7 0.6 1.1 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 KXS14127.1 - 0.004 16.8 0.7 0.0067 16.0 0.7 1.4 1 0 0 1 1 1 1 RIO1 family FTA2 PF13095.6 KXS14127.1 - 0.075 12.6 0.3 1 9.0 0.1 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DUF1883 PF08980.10 KXS14127.1 - 0.13 12.2 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1883) KH_1 PF00013.29 KXS14128.1 - 6.8e-24 83.5 0.2 6.2e-09 35.6 0.0 6.4 7 0 0 7 7 7 3 KH domain SAM_1 PF00536.30 KXS14128.1 - 1.1e-11 44.9 0.0 2.4e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KXS14128.1 - 3.2e-09 36.8 0.0 1.1e-08 35.1 0.0 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) PMSR PF01625.21 KXS14129.1 - 2e-65 219.7 0.8 2.2e-65 219.5 0.8 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase RRM_2 PF04059.12 KXS14131.1 - 2.2e-47 159.2 0.4 3.2e-47 158.7 0.4 1.2 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_1 PF00076.22 KXS14131.1 - 1.4e-05 24.8 0.0 0.012 15.5 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BRAP2 PF07576.12 KXS14131.1 - 0.00076 19.7 0.1 0.0017 18.5 0.1 1.5 1 0 0 1 1 1 1 BRCA1-associated protein 2 Smg4_UPF3 PF03467.15 KXS14131.1 - 0.038 14.0 0.0 0.23 11.4 0.0 2.0 2 0 0 2 2 2 0 Smg-4/UPF3 family Ank_5 PF13857.6 KXS14135.1 - 1.4e-07 31.7 0.0 2e-05 24.7 0.0 2.4 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXS14135.1 - 2.4e-06 28.0 0.0 2.6e-05 24.7 0.0 2.1 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KXS14135.1 - 1.7e-05 25.0 0.7 4.1e-05 23.8 0.2 1.9 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 KXS14135.1 - 0.00024 21.6 0.0 0.023 15.3 0.0 2.9 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXS14135.1 - 0.00029 21.0 0.0 0.0034 17.7 0.0 2.5 3 0 0 3 3 3 1 Ankyrin repeat Zip PF02535.22 KXS14136.1 - 3.7e-47 161.2 9.7 7e-47 160.3 9.7 1.5 1 1 0 1 1 1 1 ZIP Zinc transporter adh_short PF00106.25 KXS14137.1 - 1.7e-28 99.4 0.1 2.1e-27 95.9 0.1 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXS14137.1 - 3.3e-20 72.7 0.1 4.9e-13 49.2 0.0 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXS14137.1 - 1.6e-08 34.7 0.2 4.7e-08 33.2 0.0 1.7 2 0 0 2 2 2 1 KR domain GDP_Man_Dehyd PF16363.5 KXS14137.1 - 0.028 13.8 0.4 0.1 12.0 0.0 1.9 2 1 0 2 2 2 0 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KXS14137.1 - 0.034 13.3 0.0 0.22 10.6 0.0 1.9 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Epimerase PF01370.21 KXS14137.1 - 0.037 13.5 0.1 0.13 11.7 0.0 1.8 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family DUF3240 PF11582.8 KXS14139.1 - 0.013 15.6 0.0 0.03 14.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3240) p450 PF00067.22 KXS14140.1 - 1.4e-61 208.7 0.0 2e-61 208.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Ferritin PF00210.24 KXS14140.1 - 0.029 14.3 0.0 0.056 13.4 0.0 1.4 1 0 0 1 1 1 0 Ferritin-like domain p450 PF00067.22 KXS14141.1 - 4e-19 68.7 0.0 5.1e-19 68.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Sel1 PF08238.12 KXS14142.1 - 6.9e-95 309.3 53.5 4.1e-09 36.8 0.5 14.8 15 0 0 15 15 15 14 Sel1 repeat Pkinase_Tyr PF07714.17 KXS14142.1 - 0.00039 19.8 0.1 0.00061 19.2 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase TPR_11 PF13414.6 KXS14142.1 - 0.0014 18.3 18.9 2.6 7.8 0.0 8.7 8 0 0 8 8 8 2 TPR repeat ANAPC3 PF12895.7 KXS14142.1 - 0.0052 17.0 14.3 0.01 16.0 0.3 5.6 5 1 1 6 6 6 1 Anaphase-promoting complex, cyclosome, subunit 3 DUF3856 PF12968.7 KXS14142.1 - 0.032 14.3 3.7 0.72 9.9 0.0 3.3 3 1 0 3 3 3 0 Domain of Unknown Function (DUF3856) TPR_6 PF13174.6 KXS14142.1 - 0.33 11.7 15.0 1.6 9.5 0.4 7.4 8 2 2 10 10 10 0 Tetratricopeptide repeat TPR_16 PF13432.6 KXS14142.1 - 2.4 8.9 32.4 0.94 10.2 0.1 7.9 6 2 4 10 10 10 0 Tetratricopeptide repeat SPO22 PF08631.10 KXS14142.1 - 5.8 6.3 6.6 79 2.6 0.1 4.4 2 1 3 5 5 5 0 Meiosis protein SPO22/ZIP4 like TPR_19 PF14559.6 KXS14142.1 - 8.2 7.0 18.4 3.7 8.1 0.2 6.2 5 1 3 8 8 8 0 Tetratricopeptide repeat SnoaL_2 PF12680.7 KXS14148.1 - 6.9e-13 49.1 0.0 2.1e-12 47.5 0.0 1.8 2 0 0 2 2 2 1 SnoaL-like domain SnoaL_3 PF13474.6 KXS14148.1 - 0.00011 22.4 0.0 0.00019 21.7 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 KXS14148.1 - 0.0066 16.3 0.0 0.014 15.2 0.0 1.6 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase DUF4440 PF14534.6 KXS14148.1 - 0.042 14.2 0.0 0.063 13.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) SoxZ PF08770.11 KXS14148.1 - 0.14 12.0 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 Sulphur oxidation protein SoxZ F-box-like PF12937.7 KXS14149.1 - 1.2e-06 28.2 0.3 3e-06 27.0 0.3 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXS14149.1 - 0.17 11.8 0.6 0.59 10.1 0.6 1.9 1 1 0 1 1 1 0 F-box domain FtsJ PF01728.19 KXS14151.1 - 8.4e-29 100.9 0.1 9.2e-29 100.8 0.1 1.0 1 0 0 1 1 1 1 FtsJ-like methyltransferase zf-AD PF07776.15 KXS14152.1 - 0.14 12.4 0.1 0.33 11.2 0.0 1.7 2 0 0 2 2 2 0 Zinc-finger associated domain (zf-AD) Ribosomal_L32e PF01655.18 KXS14155.1 - 1.3e-45 154.3 0.0 1.6e-45 154.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 F-box PF00646.33 KXS14156.1 - 0.0011 18.8 0.1 0.0018 18.1 0.1 1.4 1 0 0 1 1 1 1 F-box domain PRANC PF09372.10 KXS14156.1 - 0.0035 17.6 0.0 0.0042 17.4 0.0 1.1 1 0 0 1 1 1 1 PRANC domain F-box-like PF12937.7 KXS14156.1 - 0.0044 16.9 0.3 0.0044 16.9 0.3 1.6 2 0 0 2 2 2 1 F-box-like Y_phosphatase2 PF03162.13 KXS14157.1 - 5.6e-55 185.4 0.0 6.4e-55 185.2 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 KXS14157.1 - 2e-08 34.5 0.0 2.1e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 KXS14157.1 - 6.5e-05 22.8 0.1 9.6e-05 22.2 0.1 1.5 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KXS14157.1 - 0.0011 18.6 0.0 0.0016 18.1 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Myotub-related PF06602.14 KXS14157.1 - 0.12 11.3 0.1 0.18 10.7 0.1 1.2 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain GFO_IDH_MocA PF01408.22 KXS14158.1 - 2.3e-08 34.9 0.1 1.1e-07 32.7 0.1 2.1 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KXS14158.1 - 0.0014 18.7 0.0 0.0044 17.0 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain DUF3439 PF11921.8 KXS14158.1 - 0.11 12.5 0.5 0.23 11.4 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) ABM PF03992.16 KXS14159.1 - 0.00072 19.6 0.0 0.00099 19.2 0.0 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase FHA PF00498.26 KXS14160.1 - 3.4e-17 62.5 0.0 5.7e-17 61.8 0.0 1.4 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KXS14160.1 - 0.00023 21.4 0.0 0.0014 18.9 0.0 2.0 1 1 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Arteri_nucleo PF01481.16 KXS14161.1 - 0.15 12.4 0.0 0.24 11.7 0.0 1.5 1 1 0 1 1 1 0 Arterivirus nucleocapsid protein KinB_sensor PF16767.5 KXS14161.1 - 0.15 12.5 0.0 0.25 11.8 0.0 1.3 1 0 0 1 1 1 0 Sensor domain of alginate biosynthesis sensor protein KinB Bestrophin PF01062.21 KXS14162.1 - 2.4e-36 125.7 0.4 3.4e-36 125.1 0.4 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel DnaJ PF00226.31 KXS14163.1 - 8.2e-25 86.7 2.1 1.2e-24 86.2 2.1 1.2 1 0 0 1 1 1 1 DnaJ domain Ank_2 PF12796.7 KXS14164.1 - 0.0004 20.9 0.1 1.9 9.2 0.0 2.4 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXS14164.1 - 0.036 14.7 0.8 4.7 7.9 0.1 2.6 2 1 0 2 2 2 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXS14165.1 - 0.00061 20.3 0.0 0.023 15.3 0.0 2.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXS14165.1 - 0.0051 17.2 0.1 1.1 10.0 0.0 3.7 4 0 0 4 4 4 1 Ankyrin repeat Ank_4 PF13637.6 KXS14165.1 - 0.12 12.9 0.0 12 6.6 0.1 3.2 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXS14166.1 - 8.3e-19 68.0 5.7 3.1e-07 30.9 0.1 2.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXS14166.1 - 8.1e-09 35.0 4.1 0.53 11.0 0.0 4.8 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.6 KXS14166.1 - 2.9e-08 34.1 2.3 0.082 13.5 0.1 3.8 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 KXS14166.1 - 2e-05 24.8 8.8 1.3 9.6 0.2 4.5 4 1 1 5 5 5 2 Ankyrin repeat Mur_ligase PF01225.25 KXS14166.1 - 0.0011 19.3 0.8 0.25 11.7 0.0 3.1 1 1 1 2 2 2 1 Mur ligase family, catalytic domain DUF3885 PF13021.6 KXS14166.1 - 0.014 15.5 1.3 1.3 9.2 0.0 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF3885) Ank_5 PF13857.6 KXS14166.1 - 0.084 13.2 1.7 56 4.2 0.1 3.9 4 0 0 4 4 4 0 Ankyrin repeats (many copies) AAA_12 PF13087.6 KXS14173.1 - 1.1e-14 54.5 0.0 1.4e-14 54.2 0.0 1.1 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 KXS14173.1 - 0.074 12.9 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Myb_DNA-binding PF00249.31 KXS14174.1 - 1.6e-16 60.2 0.0 4.2e-08 33.3 0.0 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KXS14174.1 - 1.5e-07 31.6 0.0 6.4e-05 23.1 0.0 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain PRIMA1 PF16101.5 KXS14176.1 - 1.5 8.9 4.5 2.6 8.1 3.6 1.8 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Far-17a_AIG1 PF04750.14 KXS14177.1 - 7.4e-25 87.5 11.8 1.1e-24 86.9 11.8 1.2 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein Umbravirus_LDM PF04817.12 KXS14178.1 - 0.03 13.7 0.0 0.042 13.2 0.0 1.2 1 0 0 1 1 1 0 Umbravirus long distance movement (LDM) family 4F5 PF04419.14 KXS14179.1 - 5.6e-10 39.9 8.5 5.6e-10 39.9 8.5 2.2 1 1 1 2 2 2 1 4F5 protein family PPR_long PF17177.4 KXS14182.1 - 0.00025 20.5 0.0 0.00036 20.0 0.0 1.2 1 0 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP PPR_2 PF13041.6 KXS14182.1 - 0.00027 21.1 0.1 0.0009 19.4 0.0 2.0 2 1 0 2 2 2 1 PPR repeat family PPR PF01535.20 KXS14182.1 - 0.00042 20.4 1.2 0.01 16.0 0.0 3.3 4 0 0 4 4 4 1 PPR repeat PPR_3 PF13812.6 KXS14182.1 - 0.092 12.8 0.0 0.21 11.7 0.0 1.6 2 0 0 2 2 2 0 Pentatricopeptide repeat domain FYVE PF01363.21 KXS14184.1 - 1.5e-16 60.3 4.3 9.1e-16 57.8 2.2 2.4 2 1 0 2 2 2 1 FYVE zinc finger zf-C2H2_4 PF13894.6 KXS14184.1 - 0.12 13.2 0.0 0.12 13.2 0.0 4.0 3 1 1 4 4 4 0 C2H2-type zinc finger zf-Di19 PF05605.12 KXS14184.1 - 0.16 12.3 8.3 0.53 10.6 0.1 2.5 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Rbsn PF11464.8 KXS14184.1 - 0.22 11.3 2.3 0.53 10.1 2.3 1.7 1 0 0 1 1 1 0 Rabenosyn Rab binding domain zf-C2H2 PF00096.26 KXS14184.1 - 0.38 11.3 0.0 0.38 11.3 0.0 3.9 3 1 1 4 4 4 0 Zinc finger, C2H2 type Prok-RING_2 PF14445.6 KXS14184.1 - 0.55 10.5 3.4 1.5 9.0 3.4 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 2 zinc_ribbon_9 PF14369.6 KXS14184.1 - 1.1 9.6 6.5 0.55 10.5 0.2 3.0 3 0 0 3 3 3 0 zinc-ribbon zinc-ribbons_6 PF07191.12 KXS14184.1 - 4.7 7.3 7.5 4.3 7.4 2.5 2.8 3 0 0 3 3 3 0 zinc-ribbons zf_C2HC_14 PF18574.1 KXS14184.1 - 4.9 7.0 6.1 1.7 8.5 1.6 2.1 2 0 0 2 2 2 0 C2HC Zing finger domain Ndufs5 PF10200.9 KXS14186.1 - 0.00023 21.4 0.3 0.00025 21.2 0.3 1.1 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa UPF0203 PF05254.12 KXS14186.1 - 0.00042 20.5 1.8 0.00053 20.2 1.8 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) CHCH PF06747.13 KXS14186.1 - 0.057 13.6 6.0 0.17 12.1 6.0 1.7 1 1 0 1 1 1 0 CHCH domain DUF3128 PF11326.8 KXS14186.1 - 0.23 11.9 3.4 2.3 8.6 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3128) CX9C PF16860.5 KXS14186.1 - 0.39 10.7 4.0 1.1 9.3 1.8 2.1 1 1 1 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, TB2_DP1_HVA22 PF03134.19 KXS14187.1 - 8.7e-28 96.1 8.6 1.5e-27 95.3 8.6 1.4 1 0 0 1 1 1 1 TB2/DP1, HVA22 family CH PF00307.31 KXS14188.1 - 8.3e-78 257.6 0.6 7.3e-21 74.4 0.2 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain CAMSAP_CH PF11971.8 KXS14188.1 - 9.9e-09 34.9 0.0 8e-05 22.4 0.0 2.9 3 0 0 3 3 3 2 CAMSAP CH domain EF-hand_5 PF13202.6 KXS14188.1 - 3.4e-05 23.1 0.5 9.3e-05 21.7 0.1 2.0 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 KXS14188.1 - 4.3e-05 23.1 0.0 0.00016 21.3 0.0 2.0 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 KXS14188.1 - 6.6e-05 23.3 0.1 0.00027 21.3 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 KXS14188.1 - 0.00019 20.7 0.0 0.00063 19.1 0.0 2.0 1 0 0 1 1 1 1 EF hand CH_2 PF06294.11 KXS14188.1 - 0.021 14.9 1.3 0.17 12.0 0.1 2.8 4 0 0 4 4 4 0 CH-like domain in sperm protein GlutR_dimer PF00745.20 KXS14188.1 - 0.042 14.3 0.6 1.5 9.3 0.0 3.3 3 1 0 3 3 3 0 Glutamyl-tRNAGlu reductase, dimerisation domain Fungal_trans PF04082.18 KXS14189.1 - 7e-17 61.3 0.1 1.4e-16 60.3 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXS14189.1 - 2.3e-05 24.4 12.5 4.4e-05 23.5 12.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain VWA_N2 PF16164.5 KXS14189.1 - 0.14 12.3 1.5 0.49 10.6 1.5 1.9 1 0 0 1 1 1 0 VWA N-terminal WD40 PF00400.32 KXS14190.1 - 6.3e-39 131.3 26.6 0.00011 22.9 0.1 11.5 11 0 0 11 11 11 10 WD domain, G-beta repeat Utp12 PF04003.12 KXS14190.1 - 3.4e-14 53.0 0.2 6.7e-14 52.1 0.2 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 KXS14190.1 - 1e-10 41.7 2.6 0.064 13.6 0.0 7.8 5 3 3 9 9 9 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KXS14190.1 - 1.5e-06 27.7 0.0 0.00028 20.3 0.0 2.5 2 0 0 2 2 2 2 WD40-like domain Nup160 PF11715.8 KXS14190.1 - 0.00021 20.1 6.4 0.19 10.3 0.7 4.4 3 2 1 4 4 4 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KXS14190.1 - 0.0043 16.1 4.6 26 3.7 0.1 5.0 2 2 3 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein FSIP1 PF15554.6 KXS14191.1 - 1.2e-09 37.9 0.0 0.0044 16.2 0.0 3.3 3 0 0 3 3 3 3 FSIP1 family adh_short PF00106.25 KXS14192.1 - 1.8e-10 40.6 0.0 2e-10 40.4 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXS14192.1 - 1.5e-06 27.9 0.0 1.7e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXS14192.1 - 0.0053 16.7 0.0 0.0059 16.5 0.0 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KXS14192.1 - 0.0087 16.0 1.0 0.011 15.6 1.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding FR47 PF08445.10 KXS14193.1 - 2.2e-13 50.0 0.0 3.6e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_1 PF00583.25 KXS14193.1 - 0.00045 20.4 0.0 0.00067 19.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXS14193.1 - 0.015 15.7 0.0 0.026 14.9 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KXS14193.1 - 0.066 13.1 0.0 0.1 12.6 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF2236 PF09995.9 KXS14194.1 - 3.8e-21 76.3 0.0 6.9e-21 75.5 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) adh_short PF00106.25 KXS14195.1 - 4.6e-18 65.4 0.0 5.6e-18 65.1 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXS14195.1 - 2.5e-13 50.1 0.0 2.8e-13 50.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXS14195.1 - 4.6e-06 26.7 0.0 5.3e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KXS14195.1 - 0.00022 21.2 0.1 0.00036 20.5 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Glyco_tran_WecB PF03808.13 KXS14195.1 - 0.0051 16.8 0.0 0.0073 16.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase WecB/TagA/CpsF family Ribosomal_L13e PF01294.18 KXS14197.1 - 5.6e-73 244.6 3.2 6.5e-73 244.4 3.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L13e Ribosomal_S9 PF00380.19 KXS14198.1 - 3.6e-30 105.0 0.1 4.1e-30 104.8 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 LRR_4 PF12799.7 KXS14200.1 - 8.7e-12 45.1 24.7 1.8e-05 25.0 0.9 5.0 2 1 4 6 6 6 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXS14200.1 - 2.8e-05 23.8 26.9 0.00061 19.5 7.1 4.0 2 2 1 3 3 3 3 Leucine rich repeat LRR_6 PF13516.6 KXS14200.1 - 0.00018 21.3 14.5 0.63 10.2 2.0 5.4 5 0 0 5 5 5 2 Leucine Rich repeat LRR_1 PF00560.33 KXS14200.1 - 0.00047 20.3 25.9 1.9 9.3 0.1 7.6 7 1 0 7 7 7 3 Leucine Rich Repeat SH3_9 PF14604.6 KXS14200.1 - 0.0013 18.5 0.0 0.0028 17.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KXS14200.1 - 0.013 15.2 0.0 0.022 14.4 0.0 1.4 1 0 0 1 1 1 0 Variant SH3 domain SH3_1 PF00018.28 KXS14200.1 - 0.022 14.4 0.0 0.038 13.6 0.0 1.3 1 0 0 1 1 1 0 SH3 domain Syndecan PF01034.20 KXS14200.1 - 0.8 9.7 2.7 1.4 8.9 2.7 1.3 1 0 0 1 1 1 0 Syndecan domain LRR_9 PF14580.6 KXS14200.1 - 1 8.9 2.5 1.2 8.6 0.2 1.9 2 0 0 2 2 2 0 Leucine-rich repeat DUF5102 PF17104.5 KXS14201.1 - 2.4e-15 57.3 8.3 2.4e-15 57.3 8.3 5.8 3 3 1 4 4 4 2 Domain of unknown function (DUF5102) FEZ PF07763.13 KXS14201.1 - 0.0025 17.6 4.3 0.0053 16.5 4.3 1.4 1 0 0 1 1 1 1 FEZ-like protein Clathrin_bdg PF15045.6 KXS14201.1 - 0.022 14.7 0.0 0.076 13.0 0.0 1.9 1 0 0 1 1 1 0 Clathrin-binding box of Aftiphilin, vesicle trafficking HNH_repeat PF18780.1 KXS14203.1 - 0.032 14.0 1.9 0.053 13.3 1.9 1.3 1 0 0 1 1 1 0 Homing endonuclease repeat tRNA-synt_1b PF00579.25 KXS14203.1 - 0.24 10.7 0.0 0.31 10.3 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (W and Y) tRNA-synt_1b PF00579.25 KXS14204.1 - 0.00087 18.7 0.0 0.001 18.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Pkinase_Tyr PF07714.17 KXS14205.1 - 6e-37 127.3 0.0 1.2e-33 116.5 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Sel1 PF08238.12 KXS14205.1 - 7e-35 118.7 33.8 4.9e-11 42.9 0.4 8.4 8 1 0 8 8 8 6 Sel1 repeat Pkinase PF00069.25 KXS14205.1 - 1.6e-28 99.8 0.0 1.8e-25 89.8 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Kinase-like PF14531.6 KXS14205.1 - 1.6e-05 24.4 0.0 3.6e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KXS14205.1 - 0.0072 16.3 0.1 0.024 14.6 0.1 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 KXS14205.1 - 0.052 13.1 0.0 0.097 12.3 0.0 1.4 1 0 0 1 1 1 0 RIO1 family TPR_1 PF00515.28 KXS14205.1 - 0.076 12.9 11.1 1.6 8.6 0.1 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Cu_amine_oxid PF01179.20 KXS14205.1 - 0.077 11.9 0.1 0.12 11.3 0.1 1.2 1 0 0 1 1 1 0 Copper amine oxidase, enzyme domain MIT PF04212.18 KXS14205.1 - 0.15 12.2 7.5 14 5.8 0.1 3.8 3 1 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_2 PF07719.17 KXS14205.1 - 6.4 7.1 24.2 4.3 7.7 0.2 6.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.6 KXS14205.1 - 6.7 7.2 11.2 21 5.7 0.1 4.3 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 KXS14205.1 - 9 6.7 9.1 7.2 7.0 0.4 3.9 3 1 0 3 3 3 0 Tetratricopeptide repeat Sel1 PF08238.12 KXS14206.1 - 3.7e-35 119.6 23.5 1.5e-08 35.0 1.1 6.5 6 0 0 6 6 6 6 Sel1 repeat Pkinase_Tyr PF07714.17 KXS14206.1 - 3.8e-12 46.0 0.0 5.9e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXS14206.1 - 0.00054 19.4 0.0 0.00093 18.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 KXS14206.1 - 0.085 12.2 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Kinase-like dCMP_cyt_deam_1 PF00383.23 KXS14207.1 - 9.5e-05 22.2 0.0 0.00017 21.4 0.0 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.6 KXS14207.1 - 0.00057 20.0 0.1 0.07 13.2 0.0 2.3 2 0 0 2 2 2 2 Bd3614-like deaminase MafB19-deam PF14437.6 KXS14207.1 - 0.00096 18.9 0.0 0.0015 18.2 0.0 1.3 1 0 0 1 1 1 1 MafB19-like deaminase Med25_VWA PF11265.8 KXS14210.1 - 0.00011 22.1 0.0 0.0071 16.2 0.0 2.2 1 1 0 1 1 1 1 Mediator complex subunit 25 von Willebrand factor type A Nucleo_P87 PF07267.11 KXS14210.1 - 0.3 9.9 0.5 0.42 9.4 0.5 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF908 PF06012.12 KXS14211.1 - 2.4e-41 142.4 0.0 4.2e-41 141.6 0.0 1.3 1 0 0 1 1 1 1 Domain of Unknown Function (DUF908) DUF913 PF06025.12 KXS14211.1 - 3e-40 138.3 2.8 6e-40 137.4 0.1 2.5 3 0 0 3 3 3 1 Domain of Unknown Function (DUF913) GFO_IDH_MocA PF01408.22 KXS14212.1 - 4e-14 53.5 0.2 1.3e-13 51.8 0.2 1.9 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold UCH PF00443.29 KXS14213.1 - 5.2e-45 153.9 0.2 8.2e-45 153.3 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KXS14213.1 - 7.7e-24 84.9 1.5 4.9e-23 82.2 0.3 2.6 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 KXS14213.1 - 1.9e-06 28.4 0.1 0.0044 17.6 0.0 3.4 3 0 0 3 3 3 1 DUSP domain zf-RanBP PF00641.18 KXS14213.1 - 6.2e-06 25.4 0.6 6.2e-06 25.4 0.6 3.0 3 0 0 3 3 3 1 Zn-finger in Ran binding protein and others ubiquitin PF00240.23 KXS14213.1 - 6.9e-06 25.7 0.0 2.6e-05 23.9 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin family UIM PF02809.20 KXS14213.1 - 0.00056 19.7 1.1 0.0016 18.3 1.1 1.8 1 0 0 1 1 1 1 Ubiquitin interaction motif PHA-1 PF06542.11 KXS14213.1 - 0.067 12.0 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Regulator protein PHA-1 Zn-ribbon_8 PF09723.10 KXS14213.1 - 5.9 7.1 13.2 17 5.6 0.2 4.9 5 0 0 5 5 5 0 Zinc ribbon domain zf-C2H2 PF00096.26 KXS14214.1 - 9.9e-12 44.6 10.4 4.4e-05 23.7 0.1 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KXS14214.1 - 3.6e-10 39.8 8.5 8.2e-08 32.3 1.6 2.8 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KXS14214.1 - 9.3e-09 35.4 8.6 0.00084 20.0 0.1 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2HE PF16278.5 KXS14214.1 - 4e-05 24.0 1.0 0.003 18.0 0.3 2.4 2 0 0 2 2 2 1 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_jaz PF12171.8 KXS14214.1 - 0.002 18.3 0.2 1.6 9.2 0.0 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KXS14214.1 - 0.0052 16.5 4.2 0.0052 16.5 4.2 2.8 2 1 0 2 2 2 1 C2H2-type zinc-finger domain Cript PF10235.9 KXS14214.1 - 0.01 16.4 0.6 0.017 15.7 0.6 1.3 1 0 0 1 1 1 0 Microtubule-associated protein CRIPT zf-LYAR PF08790.11 KXS14214.1 - 0.029 14.3 6.0 1.7 8.6 0.1 2.4 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-C2H2_11 PF16622.5 KXS14214.1 - 0.03 14.1 6.5 0.41 10.5 2.9 2.3 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-Di19 PF05605.12 KXS14214.1 - 0.031 14.6 4.6 0.04 14.2 0.4 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.7 KXS14214.1 - 0.045 14.1 2.5 5.6 7.4 0.1 2.4 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 KXS14214.1 - 0.053 13.5 5.9 0.28 11.2 0.1 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2HC_2 PF13913.6 KXS14214.1 - 0.074 13.0 1.2 0.18 11.7 1.2 1.7 1 0 0 1 1 1 0 zinc-finger of a C2HC-type zf-BED PF02892.15 KXS14214.1 - 0.1 12.7 2.2 5.7 7.1 0.2 2.4 1 1 1 2 2 2 0 BED zinc finger zf-C2H2_3rep PF18868.1 KXS14214.1 - 0.26 12.0 2.3 5.7 7.6 0.3 2.3 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-AN1 PF01428.16 KXS14214.1 - 1.2 9.4 10.0 11 6.3 3.1 2.4 1 1 1 2 2 2 0 AN1-like Zinc finger CLP_protease PF00574.23 KXS14215.1 - 4.1e-77 258.2 0.0 4.7e-77 258.0 0.0 1.0 1 0 0 1 1 1 1 Clp protease TSC22 PF01166.18 KXS14216.1 - 0.0016 18.7 3.2 0.32 11.3 0.1 3.4 3 0 0 3 3 3 1 TSC-22/dip/bun family ZapB PF06005.12 KXS14216.1 - 0.0064 16.9 11.3 0.07 13.6 2.0 3.1 3 0 0 3 3 3 1 Cell division protein ZapB UPF0449 PF15136.6 KXS14216.1 - 0.015 15.7 1.6 6.3 7.3 0.0 3.1 3 0 0 3 3 3 0 Uncharacterised protein family UPF0449 Csm1_N PF18504.1 KXS14216.1 - 0.026 14.9 12.3 0.033 14.5 2.6 3.0 3 1 0 3 3 3 0 Csm1 N-terminal domain Germane PF10646.9 KXS14216.1 - 0.03 15.1 0.1 0.056 14.2 0.1 1.5 1 1 0 1 1 1 0 Sporulation and spore germination APG6_N PF17675.1 KXS14216.1 - 0.033 14.7 5.4 1.1 9.8 0.4 2.3 2 1 0 2 2 2 0 Apg6 coiled-coil region bZIP_1 PF00170.21 KXS14216.1 - 0.044 13.9 12.9 3.4 7.8 1.5 3.4 3 0 0 3 3 3 0 bZIP transcription factor Vps51 PF08700.11 KXS14216.1 - 0.064 13.3 1.2 12 6.0 0.1 3.2 3 1 0 3 3 3 0 Vps51/Vps67 DUF4201 PF13870.6 KXS14216.1 - 0.075 12.8 11.1 0.22 11.2 2.3 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4201) Med21 PF11221.8 KXS14216.1 - 0.082 13.2 0.3 0.082 13.2 0.3 2.5 3 0 0 3 3 3 0 Subunit 21 of Mediator complex DUF948 PF06103.11 KXS14216.1 - 0.084 13.1 4.1 0.59 10.4 0.3 2.9 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF1465 PF07323.12 KXS14216.1 - 0.1 12.4 1.6 2.9 7.7 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1465) BLOC1_2 PF10046.9 KXS14216.1 - 0.11 12.8 7.6 0.26 11.6 0.2 3.1 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3972 PF13118.6 KXS14216.1 - 0.12 12.8 4.2 0.58 10.6 1.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3972) CCDC144C PF14915.6 KXS14216.1 - 0.37 9.9 7.1 0.52 9.4 0.7 2.5 2 1 0 2 2 2 0 CCDC144C protein coiled-coil region COG2 PF06148.11 KXS14216.1 - 0.45 10.6 4.8 18 5.4 0.3 3.0 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 FlaC_arch PF05377.11 KXS14216.1 - 0.53 10.7 8.9 23 5.5 0.4 3.9 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) Spc29 PF17082.5 KXS14216.1 - 0.65 9.8 5.1 0.76 9.6 2.4 2.1 1 1 0 2 2 2 0 Spindle Pole Component 29 YabA PF06156.13 KXS14216.1 - 0.7 10.6 6.4 11 6.7 0.5 3.0 2 1 1 3 3 3 0 Initiation control protein YabA Rho_Binding PF08912.11 KXS14216.1 - 0.93 10.4 7.8 8.9 7.2 0.6 3.2 3 0 0 3 3 3 0 Rho Binding HrpB7 PF09486.10 KXS14216.1 - 1.1 9.6 4.0 27 5.1 0.0 2.9 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB7) DUF4140 PF13600.6 KXS14216.1 - 1.1 9.7 6.5 5.5 7.5 0.2 3.1 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) Spc7 PF08317.11 KXS14216.1 - 1.3 7.8 8.1 7.9 5.3 1.4 2.7 3 0 0 3 3 3 0 Spc7 kinetochore protein Mod_r PF07200.13 KXS14216.1 - 1.6 8.9 7.5 3.5 7.7 0.7 2.9 3 0 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein Syntaxin_2 PF14523.6 KXS14216.1 - 1.9 8.9 7.3 18 5.8 2.5 2.9 2 1 1 3 3 3 0 Syntaxin-like protein GAS PF13851.6 KXS14216.1 - 2.2 7.6 11.4 5.6 6.3 4.0 2.8 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding BRE1 PF08647.11 KXS14216.1 - 2.3 8.3 12.3 1.8 8.7 2.2 2.8 3 0 0 3 3 3 0 BRE1 E3 ubiquitin ligase TMF_DNA_bd PF12329.8 KXS14216.1 - 3.1 7.9 14.4 6.1 6.9 4.2 3.3 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding Rootletin PF15035.6 KXS14216.1 - 3.8 7.5 8.5 3.3 7.7 1.6 2.6 2 1 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion CENP-H PF05837.12 KXS14216.1 - 4 7.9 6.8 18 5.8 0.6 2.7 3 0 0 3 3 3 0 Centromere protein H (CENP-H) Laminin_II PF06009.12 KXS14216.1 - 7 6.7 9.3 25 4.9 0.3 3.1 3 0 0 3 3 3 0 Laminin Domain II DUF4795 PF16043.5 KXS14216.1 - 8.2 6.0 8.9 3.8 7.1 0.8 2.8 2 1 0 3 3 3 0 Domain of unknown function (DUF4795) Spectrin PF00435.21 KXS14216.1 - 8.3 7.0 7.7 8.3 7.0 0.4 2.8 3 0 0 3 3 3 0 Spectrin repeat C2-C2_1 PF11618.8 KXS14217.1 - 3.5e-33 114.7 0.1 1.5e-25 89.9 0.1 2.6 2 0 0 2 2 2 2 First C2 domain of RPGR-interacting protein 1 C2 PF00168.30 KXS14217.1 - 0.00014 22.1 0.0 0.0035 17.6 0.0 2.4 2 0 0 2 2 2 1 C2 domain JIP_LZII PF16471.5 KXS14217.1 - 0.012 15.8 2.6 0.012 15.8 2.6 3.8 2 2 2 4 4 4 0 JNK-interacting protein leucine zipper II DUF755 PF05501.11 KXS14217.1 - 0.23 11.7 1.2 0.64 10.3 1.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Tup_N PF08581.10 KXS14217.1 - 0.24 11.7 0.1 0.24 11.7 0.1 4.0 3 2 1 4 4 4 0 Tup N-terminal CDC37_C PF08564.10 KXS14217.1 - 0.51 10.5 4.6 0.75 10.0 1.3 2.4 2 0 0 2 2 2 0 Cdc37 C terminal domain DUF3450 PF11932.8 KXS14217.1 - 1.6 8.0 16.8 0.26 10.5 3.2 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF948 PF06103.11 KXS14217.1 - 3.2 8.1 4.9 6.2 7.2 0.2 3.3 2 2 2 4 4 4 0 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.12 KXS14217.1 - 4 7.5 13.6 7 6.7 2.1 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Fzo_mitofusin PF04799.13 KXS14217.1 - 7.2 6.1 11.2 9.9 5.7 0.3 3.0 2 1 1 3 3 3 0 fzo-like conserved region RPGR1_C PF18111.1 KXS14218.1 - 2.3e-07 30.9 0.0 3.1e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Retinitis pigmentosa G-protein regulator interacting C-terminal AAA_33 PF13671.6 KXS14219.1 - 4e-09 36.8 0.0 6.2e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KXS14219.1 - 6.5e-05 23.5 0.0 0.00015 22.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KXS14219.1 - 0.00016 22.1 0.0 0.00022 21.7 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 KXS14219.1 - 0.00053 19.3 0.0 0.00062 19.1 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin Viral_helicase1 PF01443.18 KXS14219.1 - 0.001 18.9 0.0 0.0016 18.2 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase NACHT PF05729.12 KXS14219.1 - 0.002 18.0 0.1 0.0072 16.3 0.0 1.8 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 KXS14219.1 - 0.0021 18.3 0.0 0.0036 17.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain APS_kinase PF01583.20 KXS14219.1 - 0.0029 17.5 0.0 0.0048 16.8 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase PRK PF00485.18 KXS14219.1 - 0.0045 16.8 0.0 0.0078 16.0 0.0 1.4 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family dNK PF01712.19 KXS14219.1 - 0.0062 16.4 0.0 0.26 11.1 0.0 2.1 2 0 0 2 2 2 1 Deoxynucleoside kinase RNA_helicase PF00910.22 KXS14219.1 - 0.0064 16.9 0.0 0.01 16.2 0.0 1.3 1 0 0 1 1 1 1 RNA helicase NB-ARC PF00931.22 KXS14219.1 - 0.0083 15.3 0.1 0.013 14.7 0.1 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_30 PF13604.6 KXS14219.1 - 0.024 14.3 0.1 0.054 13.2 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 KXS14219.1 - 0.027 14.9 0.0 0.053 13.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KXS14219.1 - 0.03 14.4 0.0 0.053 13.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.9 KXS14219.1 - 0.03 13.6 0.0 0.052 12.8 0.0 1.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ATPase_2 PF01637.18 KXS14219.1 - 0.032 14.1 0.0 0.048 13.6 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea ABC_tran PF00005.27 KXS14219.1 - 0.037 14.5 0.0 0.072 13.6 0.0 1.6 1 1 0 1 1 1 0 ABC transporter IPPT PF01715.17 KXS14219.1 - 0.041 13.7 0.0 0.047 13.5 0.0 1.2 1 0 0 1 1 1 0 IPP transferase Ploopntkinase3 PF18751.1 KXS14219.1 - 0.054 13.4 0.0 0.087 12.7 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 AAA_19 PF13245.6 KXS14219.1 - 0.082 13.2 0.0 0.54 10.6 0.0 2.0 2 1 0 2 2 2 0 AAA domain AAA PF00004.29 KXS14219.1 - 0.094 13.1 0.0 0.16 12.4 0.0 1.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 KXS14219.1 - 0.1 12.5 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain RsgA_GTPase PF03193.16 KXS14219.1 - 0.15 12.0 0.0 0.36 10.7 0.0 1.7 2 0 0 2 2 2 0 RsgA GTPase Methyltr_RsmB-F PF01189.17 KXS14220.1 - 1.5e-16 60.7 0.0 2.3e-16 60.1 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 KXS14220.1 - 0.073 13.2 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase Dimer_Tnp_hAT PF05699.14 KXS14223.1 - 3.4e-12 46.0 0.0 3.6e-12 45.9 0.0 1.0 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF92 PF01940.16 KXS14226.1 - 2.7e-76 256.1 4.7 3.2e-76 255.8 4.7 1.0 1 0 0 1 1 1 1 Integral membrane protein DUF92 DNA_primase_S PF01896.19 KXS14227.1 - 1.1e-59 201.4 0.1 1.6e-59 200.9 0.1 1.2 1 0 0 1 1 1 1 DNA primase small subunit DUF2914 PF11141.8 KXS14228.1 - 0.075 12.8 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2914) DUF1003 PF06210.11 KXS14229.1 - 7.1e-16 58.2 4.9 1.3e-15 57.3 4.9 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1003) DUF667 PF05018.13 KXS14231.1 - 2.1e-93 311.2 1.2 2.3e-93 311.1 1.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF667) DDE_1 PF03184.19 KXS14231.1 - 0.1 12.2 0.1 0.13 11.9 0.1 1.2 1 0 0 1 1 1 0 DDE superfamily endonuclease NAC PF01849.18 KXS14232.1 - 3.2e-23 81.4 1.0 4.9e-23 80.9 1.0 1.3 1 0 0 1 1 1 1 NAC domain DNA_pol_E_B PF04042.16 KXS14233.1 - 4.2e-44 150.4 0.0 6.4e-44 149.8 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DUF5601 PF18151.1 KXS14233.1 - 0.027 14.8 0.1 0.049 14.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5601) UQ_con PF00179.26 KXS14237.1 - 2.7e-46 156.7 0.0 3.3e-46 156.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KXS14237.1 - 0.095 13.0 0.5 0.52 10.6 0.3 2.1 1 1 0 1 1 1 0 RWD domain LRR_4 PF12799.7 KXS14238.1 - 3.9e-19 68.4 35.8 4.9e-06 26.8 2.5 7.0 1 1 4 7 7 7 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXS14238.1 - 3.3e-13 49.2 32.4 7.4e-05 22.4 5.1 5.4 2 1 4 6 6 6 5 Leucine rich repeat SH3_9 PF14604.6 KXS14238.1 - 8.8e-06 25.5 0.0 1.9e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXS14238.1 - 1.6e-05 24.4 0.0 3.3e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 SH3 domain LRR_1 PF00560.33 KXS14238.1 - 4e-05 23.6 10.8 4.9 8.1 0.1 7.0 7 1 0 7 7 7 2 Leucine Rich Repeat LRR_9 PF14580.6 KXS14238.1 - 0.00066 19.2 3.3 1.7 8.2 0.1 3.2 1 1 2 3 3 3 3 Leucine-rich repeat LRR_6 PF13516.6 KXS14238.1 - 0.87 9.8 26.8 8.1 6.8 0.1 7.6 8 0 0 8 8 8 0 Leucine Rich repeat DUF3222 PF11519.8 KXS14239.1 - 0.43 10.8 4.2 2.3 8.5 0.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3222) Amidohydro_1 PF01979.20 KXS14241.1 - 1.6e-68 231.6 2.6 2.4e-68 231.0 2.6 1.2 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.20 KXS14241.1 - 3.1e-56 188.9 1.0 7e-56 187.8 1.0 1.7 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_gamma PF00547.18 KXS14241.1 - 1.8e-41 140.5 0.1 4e-41 139.3 0.1 1.6 1 0 0 1 1 1 1 Urease, gamma subunit Urease_beta PF00699.20 KXS14241.1 - 6.2e-41 138.4 0.1 1.9e-40 136.8 0.1 1.9 1 0 0 1 1 1 1 Urease beta subunit Amidohydro_3 PF07969.11 KXS14241.1 - 1.1e-06 28.5 1.5 1.4e-06 28.0 0.0 2.0 3 0 0 3 3 3 1 Amidohydrolase family Ephrin_rec_like PF07699.13 KXS14243.1 - 2.1e-15 56.2 31.3 1.2e-06 28.2 0.9 5.7 2 1 2 4 4 4 3 Putative ephrin-receptor like PsbX PF06596.11 KXS14244.1 - 4.3 7.4 7.1 7.3 6.7 7.1 1.3 1 0 0 1 1 1 0 Photosystem II reaction centre X protein (PsbX) PHY PF00360.20 KXS14247.1 - 0.028 13.7 2.6 0.034 13.4 2.6 1.1 1 0 0 1 1 1 0 Phytochrome region zf-MYND PF01753.18 KXS14249.1 - 1.9e-05 24.6 1.2 3.5e-05 23.8 1.2 1.4 1 0 0 1 1 1 1 MYND finger Annexin PF00191.20 KXS14250.1 - 4e-29 100.5 0.0 5.9e-09 35.9 0.0 4.3 4 0 0 4 4 4 4 Annexin Extensin_1 PF02095.15 KXS14250.1 - 6.7 7.2 7.2 36 4.9 7.2 2.4 1 0 0 1 1 1 0 Extensin-like protein repeat SKG6 PF08693.10 KXS14251.1 - 0.028 13.8 1.2 0.052 13.0 1.2 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain ELFV_dehydrog PF00208.21 KXS14252.1 - 3.5e-57 193.9 0.0 1e-56 192.4 0.0 1.8 2 0 0 2 2 2 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 KXS14252.1 - 3.5e-22 77.9 0.0 2.1e-15 55.4 0.0 2.1 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.18 KXS14252.1 - 0.039 13.8 0.0 0.36 10.7 0.0 2.5 2 0 0 2 2 2 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Flavin_Reduct PF01613.18 KXS14253.1 - 3e-16 59.9 0.1 4.3e-16 59.4 0.1 1.1 1 0 0 1 1 1 1 Flavin reductase like domain ArsB PF02040.15 KXS14254.1 - 1.2e-28 100.7 17.5 3.6e-17 62.8 6.2 2.2 2 0 0 2 2 2 2 Arsenical pump membrane protein CitMHS PF03600.16 KXS14254.1 - 7.5e-28 97.6 13.5 1.8e-26 93.0 5.5 2.3 1 1 1 2 2 2 2 Citrate transporter OATP PF03137.20 KXS14254.1 - 0.27 9.5 3.3 0.1 10.8 0.4 1.7 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Bacteriocin_IIc PF10439.9 KXS14254.1 - 9.8 6.4 10.8 1.4 9.1 1.0 2.9 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide Pribosyl_synth PF14572.6 KXS14256.1 - 8.2e-39 133.5 0.5 1.8e-38 132.4 0.5 1.6 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 KXS14256.1 - 1.6e-35 121.5 0.8 5.4e-35 119.8 0.1 2.2 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 KXS14256.1 - 1.8e-13 50.3 0.7 4.6e-13 49.0 0.4 1.8 2 0 0 2 2 2 1 Phosphoribosyl transferase domain MTS PF05175.14 KXS14257.1 - 1.1e-08 34.8 0.0 9.9e-07 28.5 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_25 PF13649.6 KXS14257.1 - 0.00028 21.5 0.0 0.00056 20.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 KXS14257.1 - 0.0058 17.6 0.0 0.029 15.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXS14257.1 - 0.05 14.3 0.0 0.14 12.9 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.12 KXS14257.1 - 0.067 13.8 0.0 0.14 12.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DUF938 PF06080.12 KXS14257.1 - 0.085 12.6 0.0 0.12 12.2 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF938) PrmA PF06325.13 KXS14257.1 - 0.14 11.5 0.0 0.25 10.7 0.0 1.3 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) UPF0020 PF01170.18 KXS14257.1 - 0.16 11.6 0.0 0.65 9.6 0.0 1.8 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 tRNA_int_endo PF01974.17 KXS14258.1 - 6.8e-08 32.5 0.0 1.5e-07 31.4 0.0 1.5 1 1 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain SelK_SelG PF10961.8 KXS14258.1 - 9.5 6.9 14.9 20 5.9 14.9 1.6 1 0 0 1 1 1 0 Selenoprotein SelK_SelG Methyltransf_25 PF13649.6 KXS14259.1 - 6.8e-08 33.1 0.0 1.6e-07 32.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXS14259.1 - 2.6e-06 28.0 0.0 4.7e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXS14259.1 - 1e-05 25.0 0.0 2.7e-05 23.6 0.0 1.6 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 KXS14259.1 - 0.00013 21.7 0.0 0.0002 21.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXS14259.1 - 0.02 15.6 0.0 0.032 15.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Collagen PF01391.18 KXS14261.1 - 0.0044 16.7 16.9 0.0044 16.7 16.9 2.8 3 0 0 3 3 3 1 Collagen triple helix repeat (20 copies) Arginosuc_synth PF00764.19 KXS14262.1 - 1.5e-157 524.8 0.0 1.8e-157 524.6 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 KXS14262.1 - 3.7e-05 23.3 0.1 7.1e-05 22.4 0.1 1.4 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 KXS14262.1 - 0.0062 15.4 0.0 0.0089 14.8 0.0 1.2 1 0 0 1 1 1 1 tRNA methyl transferase Pkinase PF00069.25 KXS14266.1 - 1.3e-44 152.6 0.0 1.5e-44 152.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS14266.1 - 1.1e-18 67.5 0.0 1.4e-18 67.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXS14266.1 - 6.1e-05 22.5 0.0 0.00011 21.7 0.0 1.4 1 1 0 1 1 1 1 Kinase-like FTA2 PF13095.6 KXS14266.1 - 0.012 15.2 0.0 0.02 14.5 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 UMP1 PF05348.11 KXS14267.1 - 3.9e-31 107.7 0.0 5.3e-31 107.3 0.0 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 Got1 PF04178.12 KXS14268.1 - 2.3e-27 95.6 12.9 3e-27 95.3 12.9 1.0 1 0 0 1 1 1 1 Got1/Sft2-like family 4HBT PF03061.22 KXS14269.1 - 1.5e-13 50.8 0.1 3e-13 49.9 0.1 1.5 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.6 KXS14269.1 - 2.3e-05 24.5 0.1 2.9e-05 24.2 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4442) ATP_bind_1 PF03029.17 KXS14271.1 - 5.7e-61 206.4 0.0 6.4e-61 206.2 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein CbiA PF01656.23 KXS14271.1 - 0.00068 19.7 0.0 0.00075 19.6 0.0 1.3 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain CLP1_P PF16575.5 KXS14271.1 - 0.00097 19.0 0.0 0.0045 16.8 0.0 2.0 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop MeaB PF03308.16 KXS14271.1 - 0.0013 17.7 0.0 0.0025 16.8 0.0 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 KXS14271.1 - 0.0014 19.1 0.0 0.0024 18.3 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain SRP54 PF00448.22 KXS14271.1 - 0.0017 18.0 0.0 0.0028 17.3 0.0 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA PF00004.29 KXS14271.1 - 0.0023 18.4 0.0 0.004 17.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KXS14271.1 - 0.0032 17.8 0.0 0.0048 17.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KXS14271.1 - 0.0033 18.0 0.1 0.009 16.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KXS14271.1 - 0.0039 16.9 0.0 0.0079 15.9 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KXS14271.1 - 0.004 17.1 0.0 0.0066 16.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KXS14271.1 - 0.0055 16.9 0.0 0.0089 16.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KXS14271.1 - 0.0059 16.3 0.0 0.0099 15.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_31 PF13614.6 KXS14271.1 - 0.0072 16.3 0.1 0.021 14.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 KXS14271.1 - 0.0088 16.5 0.3 0.016 15.7 0.3 1.4 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.7 KXS14271.1 - 0.01 14.8 0.0 0.032 13.1 0.0 1.7 1 1 1 2 2 2 0 AAA-like domain Zeta_toxin PF06414.12 KXS14271.1 - 0.036 13.4 0.0 0.061 12.6 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin cobW PF02492.19 KXS14271.1 - 0.051 13.2 0.0 0.11 12.1 0.0 1.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain KTI12 PF08433.10 KXS14271.1 - 0.055 12.9 0.0 0.078 12.4 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 SMC_N PF02463.19 KXS14271.1 - 0.068 12.6 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_14 PF13173.6 KXS14271.1 - 0.096 12.7 0.0 0.2 11.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain ArsA_ATPase PF02374.15 KXS14271.1 - 0.1 11.8 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Anion-transporting ATPase RNA_helicase PF00910.22 KXS14271.1 - 0.1 13.0 0.0 0.21 12.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase NTPase_1 PF03266.15 KXS14271.1 - 0.15 12.0 0.0 0.53 10.2 0.0 1.8 2 0 0 2 2 2 0 NTPase MipZ PF09140.11 KXS14271.1 - 0.18 11.1 0.0 9.5 5.4 0.0 2.3 2 0 0 2 2 2 0 ATPase MipZ IstB_IS21 PF01695.17 KXS14271.1 - 0.19 11.5 0.1 4.4 7.0 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein PPV_E1_C PF00519.17 KXS14271.1 - 0.2 10.5 0.0 0.3 9.9 0.0 1.1 1 0 0 1 1 1 0 Papillomavirus helicase Viral_helicase1 PF01443.18 KXS14271.1 - 0.2 11.4 0.1 0.45 10.2 0.0 1.6 1 1 1 2 2 2 0 Viral (Superfamily 1) RNA helicase Pam16 PF03656.13 KXS14272.1 - 1.6e-30 105.8 0.1 2e-30 105.4 0.1 1.0 1 0 0 1 1 1 1 Pam16 MerR_1 PF13411.6 KXS14272.1 - 0.14 12.2 0.0 0.42 10.7 0.0 1.7 1 1 1 2 2 2 0 MerR HTH family regulatory protein Mito_carr PF00153.27 KXS14273.1 - 5.1e-45 151.3 3.5 2.1e-16 59.6 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PrcB_C PF14343.6 KXS14273.1 - 0.27 11.4 1.4 2 8.6 0.1 2.5 2 0 0 2 2 2 0 PrcB C-terminal Methyltransf_8 PF05148.15 KXS14274.1 - 2e-49 168.4 0.0 6.1e-49 166.8 0.0 1.8 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_11 PF08241.12 KXS14274.1 - 0.12 13.0 0.0 0.2 12.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain FA_desaturase PF00487.24 KXS14275.1 - 1.1e-28 100.8 22.1 1.1e-28 100.8 22.1 2.1 1 1 1 2 2 2 2 Fatty acid desaturase Cyt-b5 PF00173.28 KXS14275.1 - 2.2e-18 66.2 0.3 1e-17 64.0 0.1 2.0 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain RTA1 PF04479.13 KXS14276.1 - 1.6e-16 60.5 0.2 2.6e-16 59.9 0.2 1.3 1 0 0 1 1 1 1 RTA1 like protein zf-MYND PF01753.18 KXS14277.1 - 1.3e-06 28.4 9.7 1.3e-06 28.4 9.7 1.9 2 1 0 2 2 2 1 MYND finger Use1 PF09753.9 KXS14280.1 - 0.051 13.3 0.0 0.051 13.3 0.0 1.1 1 0 0 1 1 1 0 Membrane fusion protein Use1 PMM PF03332.13 KXS14281.1 - 9.3e-102 339.5 0.0 1.1e-101 339.3 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 KXS14281.1 - 0.0087 15.8 0.0 3.6 7.2 0.0 2.1 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase VASt PF16016.5 KXS14283.1 - 1e-18 68.2 0.0 2.2e-18 67.1 0.0 1.6 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 KXS14283.1 - 6.2e-06 26.1 0.0 1.1e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 GRAM domain RDD PF06271.12 KXS14283.1 - 0.13 12.5 1.2 14 5.8 0.4 2.5 2 0 0 2 2 2 0 RDD family NAT PF04768.13 KXS14285.1 - 3.2e-44 150.6 0.1 9.3e-44 149.1 0.1 1.8 2 0 0 2 2 2 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase Semialdhyde_dh PF01118.24 KXS14285.1 - 5.8e-28 97.8 0.0 1.3e-27 96.6 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.28 KXS14285.1 - 1.3e-26 93.7 0.5 6e-26 91.5 0.1 2.1 1 1 1 2 2 2 1 Amino acid kinase family DapB_N PF01113.20 KXS14285.1 - 0.0038 17.4 0.0 0.012 15.8 0.0 1.9 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Aminotran_1_2 PF00155.21 KXS14286.1 - 1.1e-33 116.9 0.0 1.6e-33 116.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Polysacc_deac_1 PF01522.21 KXS14287.1 - 4.9e-31 107.2 0.0 8.9e-31 106.4 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 KXS14287.1 - 0.0029 16.9 0.0 0.0042 16.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 SOG2 PF10428.9 KXS14287.1 - 0.23 10.6 5.8 0.39 9.9 5.8 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein DUF3498 PF12004.8 KXS14287.1 - 5.7 6.0 7.7 8 5.5 7.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3498) Ependymin PF00811.18 KXS14288.1 - 0.1 12.9 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 Ependymin Ribosomal_L16 PF00252.18 KXS14289.1 - 1e-34 119.4 0.1 1.3e-34 119.0 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e ThiF PF00899.21 KXS14290.1 - 3.2e-18 66.0 0.0 1.4e-16 60.6 0.0 2.2 2 0 0 2 2 2 2 ThiF family MSA-2c PF12238.8 KXS14290.1 - 0.42 10.6 1.3 0.83 9.6 1.3 1.5 1 0 0 1 1 1 0 Merozoite surface antigen 2c zf-C2H2 PF00096.26 KXS14291.1 - 0.00036 20.8 0.5 0.0008 19.7 0.5 1.6 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXS14291.1 - 0.013 16.3 0.4 0.027 15.3 0.2 1.7 1 1 0 1 1 1 0 C2H2-type zinc finger Sgf11 PF08209.11 KXS14291.1 - 0.08 12.5 0.1 0.17 11.5 0.1 1.5 1 0 0 1 1 1 0 Sgf11 (transcriptional regulation protein) DUF1610 PF07754.11 KXS14291.1 - 0.095 12.7 0.8 0.24 11.4 0.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1610) Rad50_zn_hook PF04423.14 KXS14291.1 - 0.18 11.7 0.1 0.33 10.8 0.1 1.4 1 0 0 1 1 1 0 Rad50 zinc hook motif zf-C2HC_2 PF13913.6 KXS14291.1 - 0.91 9.5 3.7 1.1 9.2 2.1 2.0 1 1 1 2 2 2 0 zinc-finger of a C2HC-type SH3_9 PF14604.6 KXS14294.1 - 0.0013 18.6 0.0 0.0039 17.0 0.1 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 KXS14294.1 - 0.0018 17.8 0.0 0.0028 17.2 0.0 1.3 1 0 0 1 1 1 1 SH3 domain Beta-APP PF03494.13 KXS14294.1 - 0.2 11.6 3.3 0.33 10.8 3.3 1.3 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) ADH_zinc_N PF00107.26 KXS14295.1 - 4e-11 43.0 0.0 7.5e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXS14295.1 - 1.7e-09 37.5 0.0 4e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Pyr_redox_3 PF13738.6 KXS14295.1 - 0.049 12.9 0.5 5.9 6.0 0.1 2.6 2 1 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Cyt-b5 PF00173.28 KXS14297.1 - 9.5e-21 73.7 0.1 3.4e-20 72.0 0.1 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.13 KXS14297.1 - 8.8e-12 45.5 17.8 8.8e-12 45.5 17.8 2.0 1 1 1 2 2 2 1 Fatty acid hydroxylase superfamily Glyco_hydro_5_C PF18564.1 KXS14298.1 - 6.7e-07 29.8 0.0 1.1e-06 29.1 0.0 1.3 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain Cellulase PF00150.18 KXS14298.1 - 0.0043 16.5 0.0 0.0071 15.8 0.0 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) SCP2 PF02036.17 KXS14299.1 - 1.8e-46 156.8 3.7 2.4e-22 79.3 0.2 2.1 2 0 0 2 2 2 2 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 KXS14299.1 - 2.4e-09 37.5 1.0 0.00094 19.5 0.1 2.2 2 0 0 2 2 2 2 Alkyl sulfatase C-terminal SCP_3 PF17844.1 KXS14299.1 - 0.049 13.4 0.0 16 5.4 0.0 2.7 3 0 0 3 3 3 0 Bacterial SCP ortholog CITED PF04487.12 KXS14299.1 - 0.094 12.8 0.2 2.6 8.0 0.2 2.2 1 1 1 2 2 2 0 CITED Sec61_beta PF03911.16 KXS14300.1 - 2.4e-16 59.5 0.9 3.3e-16 59.0 0.9 1.2 1 0 0 1 1 1 1 Sec61beta family LRR_6 PF13516.6 KXS14301.1 - 4.3e-06 26.3 3.3 0.12 12.5 0.0 3.7 3 0 0 3 3 3 2 Leucine Rich repeat LRR_8 PF13855.6 KXS14301.1 - 0.002 17.9 4.0 0.41 10.4 0.4 3.3 3 1 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 KXS14301.1 - 0.0046 17.3 8.5 0.014 15.8 0.7 4.0 3 1 1 4 4 4 1 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KXS14301.1 - 0.19 11.2 0.1 0.32 10.5 0.1 1.4 1 0 0 1 1 1 0 Leucine-rich repeat Ribosomal_S17_N PF16205.5 KXS14302.1 - 2.8e-32 110.9 0.2 2.8e-32 110.9 0.2 1.7 2 0 0 2 2 2 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 KXS14302.1 - 2.3e-26 91.6 0.5 4.2e-26 90.8 0.5 1.4 1 0 0 1 1 1 1 Ribosomal protein S17 Cyclin_N PF00134.23 KXS14303.1 - 9e-48 161.2 0.5 1.6e-44 150.7 0.3 2.1 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 KXS14303.1 - 4.5e-35 120.3 0.2 8.5e-35 119.4 0.1 1.5 2 0 0 2 2 2 1 Cyclin, C-terminal domain Bac_surface_Ag PF01103.23 KXS14304.1 - 1.7e-42 146.1 0.0 2.1e-42 145.8 0.0 1.1 1 0 0 1 1 1 1 Surface antigen POTRA PF07244.15 KXS14304.1 - 0.00064 20.3 0.0 0.001 19.6 0.0 1.4 1 0 0 1 1 1 1 Surface antigen variable number repeat Pkinase PF00069.25 KXS14305.1 - 2.7e-05 23.7 0.0 3.4e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain F-box PF00646.33 KXS14308.1 - 6.1e-05 22.8 1.3 0.00016 21.5 1.3 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KXS14308.1 - 0.00033 20.5 0.3 0.00063 19.6 0.3 1.5 1 0 0 1 1 1 1 F-box-like DUF2236 PF09995.9 KXS14309.1 - 2e-09 38.0 0.0 1.3e-06 28.8 0.0 2.2 2 0 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2236) Sugar_tr PF00083.24 KXS14312.1 - 1.3e-94 317.6 25.2 1.5e-94 317.4 25.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXS14312.1 - 1.2e-38 133.0 19.5 1.2e-38 133.0 19.5 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KXS14312.1 - 0.0015 17.0 1.8 0.0015 17.0 1.8 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF3792 PF12670.7 KXS14312.1 - 0.051 13.7 22.3 0.64 10.2 5.7 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3792) Peptidase_M55 PF04951.13 KXS14313.1 - 8.3e-29 100.8 0.2 1.5e-28 99.9 0.2 1.4 1 1 0 1 1 1 1 D-aminopeptidase DUF1598 PF07643.11 KXS14313.1 - 0.023 14.9 0.0 0.034 14.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1598) DUF4145 PF13643.6 KXS14314.1 - 0.11 12.7 0.0 0.32 11.1 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4145) RhoGAP PF00620.27 KXS14315.1 - 1.6e-36 125.4 0.0 1.9e-36 125.2 0.0 1.0 1 0 0 1 1 1 1 RhoGAP domain CoA_transf_3 PF02515.17 KXS14316.1 - 7.8e-75 252.3 0.2 3.3e-74 250.2 0.2 2.0 1 1 0 1 1 1 1 CoA-transferase family III Ser_hydrolase PF06821.13 KXS14316.1 - 0.12 12.2 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase MSC PF09402.10 KXS14318.1 - 2.5e-23 83.1 0.0 4.5e-23 82.3 0.0 1.4 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain Thymopoietin PF08198.11 KXS14318.1 - 7.2e-11 41.5 0.0 3.9e-10 39.1 0.1 2.1 2 0 0 2 2 2 1 Thymopoietin protein HeH PF12949.7 KXS14318.1 - 9.4e-09 34.8 0.1 1.7e-08 34.0 0.1 1.4 1 0 0 1 1 1 1 HeH/LEM domain DUF3231 PF11553.8 KXS14318.1 - 0.089 12.4 0.1 0.15 11.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3231) FAD_binding_3 PF01494.19 KXS14319.1 - 2.3e-16 60.0 0.0 4.2e-08 32.8 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 KXS14319.1 - 0.00076 18.8 0.0 0.0013 18.1 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KXS14319.1 - 0.057 12.3 0.0 0.084 11.7 0.0 1.1 1 0 0 1 1 1 0 Tryptophan halogenase ECH_1 PF00378.20 KXS14320.1 - 4.6e-58 196.5 0.0 6e-58 196.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXS14320.1 - 3.5e-37 128.6 0.1 2.1e-35 122.8 0.1 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 KXS14320.1 - 0.014 15.3 0.1 0.14 12.1 0.0 2.1 2 0 0 2 2 2 0 Peptidase family S49 CLP_protease PF00574.23 KXS14320.1 - 0.017 15.0 0.2 5.3 6.9 0.2 2.4 1 1 1 2 2 2 0 Clp protease Mannosyl_trans3 PF11051.8 KXS14321.1 - 0.0076 15.6 0.0 0.011 15.2 0.0 1.1 1 0 0 1 1 1 1 Mannosyltransferase putative Abhydrolase_1 PF00561.20 KXS14323.1 - 4.5e-13 49.4 0.0 6.8e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 KXS14323.1 - 1.5e-12 46.9 0.0 2.8e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Hydrolase_4 PF12146.8 KXS14323.1 - 0.0016 17.8 0.0 0.002 17.4 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 CH PF00307.31 KXS14325.1 - 4.4e-28 97.6 0.0 5.7e-13 49.0 0.0 2.7 2 1 0 2 2 2 2 Calponin homology (CH) domain Remorin_C PF03763.13 KXS14325.1 - 0.17 11.7 2.0 0.41 10.6 2.0 1.5 1 0 0 1 1 1 0 Remorin, C-terminal region FA_desaturase PF00487.24 KXS14326.1 - 1.1e-28 100.7 24.1 1.1e-28 100.7 24.1 2.1 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.28 KXS14326.1 - 0.0021 18.2 0.0 0.011 15.9 0.0 2.1 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Tyr-DNA_phospho PF06087.12 KXS14327.1 - 4.4e-48 164.2 0.1 5.3e-48 164.0 0.1 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase Methyltransf_16 PF10294.9 KXS14328.1 - 5.2e-05 23.0 0.0 0.00019 21.2 0.0 1.7 2 0 0 2 2 2 1 Lysine methyltransferase Methyltransf_12 PF08242.12 KXS14328.1 - 0.19 12.5 0.0 0.26 12.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Complex1_30kDa PF00329.19 KXS14329.1 - 1.4e-45 154.9 0.1 2e-45 154.4 0.1 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit MPC PF03650.13 KXS14330.1 - 0.079 13.1 0.0 0.24 11.5 0.0 1.9 1 0 0 1 1 1 0 Mitochondrial pyruvate carriers Pex26 PF07163.12 KXS14331.1 - 0.0031 16.9 0.3 0.014 14.8 0.0 2.0 2 0 0 2 2 2 1 Pex26 protein Adaptin_N PF01602.20 KXS14332.1 - 2.3e-138 462.0 5.3 2.8e-138 461.8 5.3 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KXS14332.1 - 3.8e-65 218.9 2.3 6.6e-64 214.8 0.1 3.0 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KXS14332.1 - 1.2e-15 57.6 4.3 1.4e-07 31.8 0.1 5.7 2 2 6 8 8 8 4 HEAT repeats HEAT PF02985.22 KXS14332.1 - 5.5e-09 35.5 2.7 0.0034 17.5 0.0 4.3 5 0 0 5 5 5 2 HEAT repeat HEAT_EZ PF13513.6 KXS14332.1 - 9.8e-06 26.0 2.2 0.14 12.7 0.1 4.0 4 0 0 4 4 3 2 HEAT-like repeat Alpha_adaptinC2 PF02883.20 KXS14332.1 - 6.1e-05 23.3 1.0 6.1e-05 23.3 1.0 2.1 2 0 0 2 2 2 1 Adaptin C-terminal domain RTP1_C1 PF10363.9 KXS14332.1 - 0.00089 19.4 0.1 1.3 9.3 0.0 3.5 2 1 1 3 3 3 2 Required for nuclear transport of RNA pol II C-terminus 1 UNC45-central PF11701.8 KXS14332.1 - 0.014 15.3 2.4 3.5 7.6 0.1 3.7 3 1 0 3 3 3 0 Myosin-binding striated muscle assembly central CLASP_N PF12348.8 KXS14332.1 - 0.041 13.4 0.2 2.4 7.7 0.0 3.3 3 1 1 4 4 4 0 CLASP N terminal Arm PF00514.23 KXS14332.1 - 0.048 13.7 3.7 1.9 8.7 0.1 4.3 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Aminoglyc_resit PF10706.9 KXS14332.1 - 0.079 12.7 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Aminoglycoside-2''-adenylyltransferase Atx10homo_assoc PF09759.9 KXS14332.1 - 0.13 12.3 0.9 50 4.0 0.0 4.3 4 1 0 5 5 5 0 Spinocerebellar ataxia type 10 protein domain Abhydrolase_6 PF12697.7 KXS14333.1 - 5.2e-06 27.2 0.9 6.2e-06 27.0 0.9 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXS14333.1 - 2.1e-05 23.9 0.1 0.00047 19.5 0.1 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 LIP PF03583.14 KXS14333.1 - 0.0025 17.2 0.3 0.0047 16.3 0.3 1.3 1 0 0 1 1 1 1 Secretory lipase PhrC_PhrF PF11131.8 KXS14334.1 - 0.15 11.7 1.3 0.3 10.7 1.3 1.5 1 0 0 1 1 1 0 Rap-phr extracellular signalling Hydrolase_4 PF12146.8 KXS14341.1 - 6.8e-10 38.6 0.0 3e-05 23.4 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KXS14341.1 - 5.5e-06 26.0 0.2 0.016 14.7 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 KXS14341.1 - 1.2e-05 26.1 0.9 1.5e-05 25.7 0.9 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family LIP PF03583.14 KXS14341.1 - 0.0001 21.8 0.8 0.00079 18.8 0.8 1.9 2 0 0 2 2 2 1 Secretory lipase Aminotran_4 PF01063.19 KXS14342.1 - 1.3e-20 74.2 0.0 1.6e-20 73.9 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV Abhydrolase_6 PF12697.7 KXS14344.1 - 2.5e-07 31.5 2.0 3.6e-07 31.0 2.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXS14344.1 - 0.019 14.6 0.8 3.9 7.1 0.6 3.0 2 1 0 2 2 2 0 alpha/beta hydrolase fold Ser_hydrolase PF06821.13 KXS14344.1 - 0.039 13.8 0.2 0.075 12.9 0.1 1.5 2 0 0 2 2 2 0 Serine hydrolase Hydrolase_4 PF12146.8 KXS14344.1 - 0.059 12.6 0.2 0.13 11.5 0.2 1.6 1 1 0 1 1 1 0 Serine aminopeptidase, S33 Acyl-CoA_dh_1 PF00441.24 KXS14345.1 - 1.9e-39 135.3 0.8 4.6e-39 134.0 0.4 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KXS14345.1 - 8.8e-29 100.5 0.0 1.8e-28 99.5 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KXS14345.1 - 3.7e-25 87.9 0.0 6.5e-25 87.2 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KXS14345.1 - 1.2e-17 64.5 0.1 1.7e-17 64.0 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain ACOX PF01756.19 KXS14345.1 - 0.082 12.5 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Acyl-CoA oxidase Pkinase PF00069.25 KXS14346.1 - 5.7e-46 157.0 0.0 1.5e-45 155.6 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS14346.1 - 2.8e-20 72.7 0.0 2.1e-13 50.2 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KXS14346.1 - 0.0023 17.9 0.1 0.0095 15.9 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KXS14346.1 - 0.0026 17.1 0.0 0.0048 16.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KXS14346.1 - 0.0032 16.8 0.1 0.031 13.6 0.0 2.1 2 0 0 2 2 2 1 Kinase-like CBFD_NFYB_HMF PF00808.23 KXS14347.1 - 4.7e-18 65.2 0.5 5.9e-18 64.9 0.5 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KXS14347.1 - 2.5e-14 53.7 0.5 3.2e-14 53.4 0.5 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.10 KXS14347.1 - 0.00082 19.6 0.1 0.0011 19.2 0.1 1.2 1 0 0 1 1 1 1 CENP-S associating Centromere protein X CENP-T_C PF15511.6 KXS14347.1 - 0.041 14.0 0.2 0.052 13.7 0.2 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold PALP PF00291.25 KXS14348.1 - 2.3e-33 115.9 0.6 5.1e-32 111.5 0.6 2.4 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Exo_endo_phos PF03372.23 KXS14349.1 - 3.6e-19 69.2 0.0 6.6e-19 68.3 0.0 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 KXS14349.1 - 0.0053 16.6 0.0 0.02 14.8 0.0 2.0 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Caleosin PF05042.13 KXS14350.1 - 5.7e-68 228.1 0.1 1.6e-62 210.4 0.0 2.1 2 0 0 2 2 2 2 Caleosin related protein EF-hand_1 PF00036.32 KXS14350.1 - 3.8e-06 26.1 0.5 0.00011 21.5 0.0 2.9 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.6 KXS14350.1 - 5.2e-06 26.0 0.2 0.00017 21.2 0.0 2.9 3 0 0 3 3 3 1 EF-hand domain EF-hand_8 PF13833.6 KXS14350.1 - 7.2e-05 22.6 0.5 0.00077 19.3 0.0 2.5 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_7 PF13499.6 KXS14350.1 - 0.00084 19.7 0.1 0.023 15.2 0.0 2.5 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 KXS14350.1 - 0.015 14.8 4.5 1.7 8.2 0.0 3.4 3 0 0 3 3 3 0 EF hand zf-MYND PF01753.18 KXS14351.1 - 9e-05 22.5 12.1 9e-05 22.5 12.1 1.9 2 0 0 2 2 2 1 MYND finger Shisa PF13908.6 KXS14351.1 - 0.0026 18.0 0.8 0.0044 17.3 0.8 1.3 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator PPR_2 PF13041.6 KXS14352.1 - 3.9e-16 59.0 0.0 2.3e-06 27.7 0.0 3.6 4 0 0 4 4 4 2 PPR repeat family PPR_1 PF12854.7 KXS14352.1 - 5.4e-11 42.0 0.0 8.3e-06 25.4 0.0 4.0 4 0 0 4 4 4 2 PPR repeat PPR PF01535.20 KXS14352.1 - 5.6e-09 35.7 0.1 3e-05 24.0 0.0 4.2 4 0 0 4 4 4 1 PPR repeat PPR_3 PF13812.6 KXS14352.1 - 8.3e-09 35.4 0.0 0.0048 16.9 0.0 2.8 2 1 0 2 2 2 2 Pentatricopeptide repeat domain PPR_long PF17177.4 KXS14352.1 - 3.8e-05 23.1 0.0 0.011 15.2 0.0 2.7 1 1 1 2 2 2 2 Pentacotripeptide-repeat region of PRORP DUF3368 PF11848.8 KXS14352.1 - 0.0047 16.7 0.0 0.024 14.4 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3368) RPM2 PF08579.11 KXS14352.1 - 0.031 14.7 0.0 10 6.6 0.0 3.3 3 1 1 4 4 4 0 Mitochondrial ribonuclease P subunit (RPM2) TPR_14 PF13428.6 KXS14352.1 - 0.066 14.1 0.1 2 9.5 0.0 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 KXS14352.1 - 0.097 13.2 0.1 1.5 9.4 0.1 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat KH_1 PF00013.29 KXS14353.1 - 1.6e-47 159.2 13.2 7.4e-18 64.1 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 KXS14353.1 - 2e-16 59.6 7.6 6e-05 22.8 0.0 3.2 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 KXS14353.1 - 1e-07 31.7 3.7 0.0059 16.5 0.1 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 KXS14353.1 - 0.00021 21.3 9.2 0.12 12.5 0.2 3.4 3 0 0 3 3 3 3 NusA-like KH domain DUF3148 PF11347.8 KXS14353.1 - 0.094 12.5 0.1 0.26 11.0 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3148) ThiF PF00899.21 KXS14354.1 - 6.4e-62 209.1 0.0 9.2e-62 208.6 0.0 1.1 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 KXS14354.1 - 0.0007 20.1 0.0 0.0018 18.7 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain UDPG_MGDP_dh_N PF03721.14 KXS14354.1 - 0.0017 17.9 0.1 0.0028 17.3 0.1 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Sacchrp_dh_NADP PF03435.18 KXS14354.1 - 0.0074 16.5 0.1 0.024 14.9 0.1 1.8 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Pyr_redox_2 PF07992.14 KXS14354.1 - 0.089 12.0 0.1 1.4 8.1 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 KXS14354.1 - 0.11 12.6 0.2 0.4 10.7 0.0 1.9 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Shugoshin_N PF07558.11 KXS14354.1 - 0.59 10.1 2.0 3.1 7.7 0.3 2.3 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region GDP_Man_Dehyd PF16363.5 KXS14355.1 - 1.2e-161 537.7 0.0 1.4e-161 537.5 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KXS14355.1 - 1.1e-74 250.9 0.0 1.6e-74 250.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KXS14355.1 - 3.7e-07 29.5 0.0 5.3e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KXS14355.1 - 0.00085 18.5 0.0 0.0013 17.9 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 KXS14355.1 - 0.0031 17.1 0.0 0.0051 16.4 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.25 KXS14356.1 - 1.4e-12 47.5 0.0 2.2e-08 33.8 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXS14356.1 - 4.1e-06 26.5 0.0 0.00013 21.6 0.0 2.1 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase DUF3859 PF12975.7 KXS14356.1 - 0.048 13.6 0.0 0.082 12.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3859) Somatostatin PF03002.15 KXS14356.1 - 0.23 11.4 0.3 0.43 10.5 0.3 1.3 1 0 0 1 1 1 0 Somatostatin/Cortistatin family Chitin_synth_2 PF03142.15 KXS14358.1 - 2e-247 822.0 0.1 2e-247 822.0 0.1 1.3 2 0 0 2 2 2 1 Chitin synthase Glyco_trans_2_3 PF13632.6 KXS14358.1 - 7.6e-12 45.6 1.0 3.7e-11 43.3 1.0 2.3 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KXS14358.1 - 8.7e-09 35.6 0.0 1.4e-07 31.6 0.0 2.2 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KXS14358.1 - 0.0055 16.2 0.0 0.048 13.1 0.0 2.4 3 0 0 3 3 3 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 KXS14358.1 - 0.032 14.0 0.0 0.82 9.5 0.0 2.5 2 0 0 2 2 2 0 Glycosyl transferase family 2 SKA1 PF07160.12 KXS14359.1 - 1.8e-35 122.9 0.0 2.4e-35 122.6 0.0 1.1 1 0 0 1 1 1 1 Spindle and kinetochore-associated protein 1 Tmemb_cc2 PF10267.9 KXS14361.1 - 0.0017 17.6 2.6 0.002 17.4 2.6 1.1 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein HEPN_STY4199 PF18729.1 KXS14361.1 - 0.0091 15.2 0.3 0.0091 15.2 0.3 1.4 2 0 0 2 2 2 1 STY4199-like HEPN FUSC PF04632.12 KXS14361.1 - 0.42 9.1 3.7 0.43 9.1 3.7 1.2 1 1 0 1 1 1 0 Fusaric acid resistance protein family BSD PF03909.17 KXS14362.1 - 4.4e-05 23.4 0.1 0.015 15.2 0.1 2.8 2 0 0 2 2 2 2 BSD domain UQ_con PF00179.26 KXS14363.1 - 6.3e-11 42.1 0.1 2.9e-10 40.0 0.1 1.9 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KXS14363.1 - 0.0016 18.1 0.0 0.0024 17.6 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KXS14363.1 - 0.017 15.4 0.0 0.03 14.6 0.0 1.3 1 1 0 1 1 1 0 RWD domain Prok-E2_A PF14457.6 KXS14363.1 - 0.036 13.7 0.0 0.069 12.8 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic E2 family A HEAT_2 PF13646.6 KXS14364.1 - 7.9e-07 29.4 6.0 0.0015 18.9 0.4 5.7 4 1 2 6 6 6 3 HEAT repeats HEAT PF02985.22 KXS14364.1 - 0.00028 20.9 2.5 19 5.9 0.0 6.0 6 0 0 6 6 6 1 HEAT repeat MRG PF05712.13 KXS14364.1 - 0.0052 16.1 1.3 0.022 14.1 0.0 2.5 2 1 0 2 2 2 1 MRG HEAT_EZ PF13513.6 KXS14364.1 - 0.06 13.9 0.7 53 4.5 0.0 4.2 3 1 1 4 4 4 0 HEAT-like repeat U3snoRNP10 PF12397.8 KXS14364.1 - 0.31 11.4 1.5 11 6.4 0.1 3.8 3 0 0 3 3 3 0 U3 small nucleolar RNA-associated protein 10 ANTH PF07651.16 KXS14365.1 - 6.2e-36 123.8 0.0 1.1e-35 123.0 0.0 1.4 1 0 0 1 1 1 1 ANTH domain Spt20 PF12090.8 KXS14365.1 - 0.012 15.2 13.5 0.012 15.2 13.5 2.2 2 0 0 2 2 2 0 Spt20 family SUIM_assoc PF16619.5 KXS14365.1 - 0.92 9.6 22.1 0.6 10.2 12.6 3.7 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 SARAF PF06682.12 KXS14365.1 - 2.6 7.6 12.8 5.1 6.7 12.7 1.5 1 1 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis DUF4407 PF14362.6 KXS14365.1 - 5.3 6.3 9.1 8.8 5.6 9.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Mitoc_L55 PF09776.9 KXS14366.1 - 0.0052 16.5 0.0 0.0078 15.9 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L55 Ribosomal_L31 PF01197.18 KXS14366.1 - 0.012 15.8 0.0 0.025 14.8 0.0 1.6 2 0 0 2 2 2 0 Ribosomal protein L31 BRE1 PF08647.11 KXS14368.1 - 0.00057 19.9 10.9 0.022 14.8 1.7 3.5 3 1 0 3 3 3 2 BRE1 E3 ubiquitin ligase Tropomyosin PF00261.20 KXS14368.1 - 1.6 8.0 0.0 1.6 8.0 0.0 3.3 3 1 0 3 3 3 0 Tropomyosin DUF1192 PF06698.11 KXS14368.1 - 2.5 8.2 6.6 1.6 8.8 0.7 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF1192) DUF3138 PF11336.8 KXS14368.1 - 4.3 5.8 8.9 1.3 7.6 2.5 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3138) ADIP PF11559.8 KXS14368.1 - 4.6 7.3 9.6 6.8 6.8 1.9 3.3 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding LRR_6 PF13516.6 KXS14370.1 - 1.9e-49 161.5 46.1 5.9e-06 25.9 0.0 13.3 13 0 0 13 13 13 12 Leucine Rich repeat LRR_4 PF12799.7 KXS14370.1 - 1.7e-23 82.3 33.4 6.9e-05 23.1 2.9 9.2 3 2 7 11 11 11 10 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXS14370.1 - 2.9e-20 71.8 40.0 0.00015 21.4 5.3 10.0 5 4 3 8 8 8 8 Leucine rich repeat LRR_1 PF00560.33 KXS14370.1 - 9.3e-15 52.9 16.4 2.3 9.1 0.1 12.0 11 2 1 12 12 12 5 Leucine Rich Repeat Moricin PF06451.11 KXS14370.1 - 2.6e-06 27.1 22.1 1.2 9.0 0.5 8.9 9 1 1 10 10 10 3 Moricin Pkinase_Tyr PF07714.17 KXS14371.1 - 4e-36 124.6 0.0 5e-36 124.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXS14371.1 - 3e-35 121.9 0.0 4.1e-35 121.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KXS14371.1 - 5.5e-05 23.2 0.0 0.00011 22.2 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KXS14371.1 - 0.00043 19.7 0.0 0.00057 19.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KXS14371.1 - 0.0021 17.5 0.0 0.0031 16.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 KXS14371.1 - 0.0039 16.2 0.0 0.0051 15.8 0.0 1.1 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase RIO1 PF01163.22 KXS14371.1 - 0.014 15.0 0.0 0.021 14.4 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Seadorna_VP7 PF07387.11 KXS14371.1 - 0.14 11.2 0.1 0.23 10.5 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 HBS1_N PF08938.10 KXS14372.1 - 4.1e-06 27.0 7.2 6.6e-06 26.3 7.2 1.3 1 0 0 1 1 1 1 HBS1 N-terminus UBA_4 PF14555.6 KXS14372.1 - 5.7e-06 26.0 0.5 1.2e-05 25.0 0.5 1.6 1 0 0 1 1 1 1 UBA-like domain CUE PF02845.16 KXS14372.1 - 0.0079 15.9 0.1 0.015 15.0 0.1 1.5 1 0 0 1 1 1 1 CUE domain DUF1296 PF06972.11 KXS14372.1 - 0.011 15.9 0.6 0.036 14.2 0.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1296) YL1 PF05764.13 KXS14372.1 - 0.048 13.8 6.2 0.064 13.4 6.2 1.1 1 0 0 1 1 1 0 YL1 nuclear protein E3_UbLigase_EDD PF11547.8 KXS14372.1 - 0.15 11.8 0.0 0.15 11.8 0.0 1.6 2 0 0 2 2 2 0 E3 ubiquitin ligase EDD GTP_EFTU PF00009.27 KXS14373.1 - 1.2e-42 145.6 0.0 1.9e-42 145.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KXS14373.1 - 4e-23 81.9 0.1 1e-22 80.5 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KXS14373.1 - 9e-10 38.8 0.2 1.9e-09 37.8 0.2 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KXS14373.1 - 1.3e-08 34.9 0.0 0.00019 21.5 0.0 2.8 2 1 1 3 3 3 2 50S ribosome-binding GTPase cobW PF02492.19 KXS14373.1 - 0.0019 17.8 0.4 11 5.6 0.0 3.3 3 0 0 3 3 3 2 CobW/HypB/UreG, nucleotide-binding domain GTP_EFTU_D4 PF14578.6 KXS14373.1 - 0.0021 17.9 0.1 0.0072 16.2 0.1 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Arf PF00025.21 KXS14373.1 - 0.0025 17.3 0.0 0.065 12.7 0.0 2.2 2 0 0 2 2 2 1 ADP-ribosylation factor family AAA_29 PF13555.6 KXS14373.1 - 0.13 12.1 0.0 0.4 10.5 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain HSP70 PF00012.20 KXS14374.1 - 3.1e-257 854.6 9.1 3.5e-257 854.4 9.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KXS14374.1 - 6.9e-17 61.2 0.5 3.6e-15 55.6 0.3 2.2 2 0 0 2 2 2 1 MreB/Mbl protein Radial_spoke_3 PF06098.11 KXS14374.1 - 0.0018 17.6 6.2 0.0018 17.6 6.2 1.6 2 0 0 2 2 2 1 Radial spoke protein 3 Hydantoinase_A PF01968.18 KXS14374.1 - 0.002 17.4 5.2 0.014 14.6 0.2 3.2 2 1 1 3 3 3 1 Hydantoinase/oxoprolinase FtsA PF14450.6 KXS14374.1 - 0.0052 17.2 3.8 5 7.6 0.1 3.9 3 2 0 3 3 3 2 Cell division protein FtsA DDR PF08841.10 KXS14374.1 - 0.006 15.6 0.6 0.028 13.4 0.3 2.0 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain CorC_HlyC PF03471.17 KXS14374.1 - 0.088 12.8 0.3 0.62 10.1 0.1 2.5 2 0 0 2 2 2 0 Transporter associated domain DIOX_N PF14226.6 KXS14374.1 - 0.27 12.0 2.3 0.82 10.4 0.3 2.4 2 0 0 2 2 2 0 non-haem dioxygenase in morphine synthesis N-terminal Ribosomal_L14 PF00238.19 KXS14375.1 - 1.8e-40 137.8 4.5 2.3e-40 137.5 4.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e DUF2518 PF10726.9 KXS14375.1 - 0.1 12.2 0.1 0.15 11.7 0.1 1.2 1 0 0 1 1 1 0 Protein of function (DUF2518) COesterase PF00135.28 KXS14376.1 - 3e-73 247.4 0.2 4e-73 247.1 0.2 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXS14376.1 - 6.6e-08 32.7 2.3 0.0043 16.9 0.1 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold Pro_Al_protease PF02983.14 KXS14376.1 - 2.4 8.3 5.0 23 5.2 0.0 3.5 3 0 0 3 3 3 0 Alpha-lytic protease prodomain Actin PF00022.19 KXS14377.1 - 7e-46 156.6 0.0 2.4e-30 105.5 0.0 2.2 2 0 0 2 2 2 2 Actin HTH_AsnC-type PF13404.6 KXS14377.1 - 0.14 12.0 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain Nop14 PF04147.12 KXS14377.1 - 0.21 9.8 0.0 0.31 9.2 0.0 1.2 1 0 0 1 1 1 0 Nop14-like family Prefoldin PF02996.17 KXS14378.1 - 5.7e-28 97.2 0.0 1.1e-27 96.3 0.0 1.5 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.20 KXS14378.1 - 0.0052 16.7 3.4 0.035 14.0 0.1 2.3 2 1 0 2 2 2 1 Prefoldin subunit LOH1CR12 PF10158.9 KXS14378.1 - 0.029 14.4 0.4 0.13 12.3 0.0 1.9 2 0 0 2 2 2 0 Tumour suppressor protein UPF0449 PF15136.6 KXS14378.1 - 0.16 12.4 2.6 5.8 7.4 0.1 2.4 2 1 0 2 2 2 0 Uncharacterised protein family UPF0449 CDC45 PF02724.14 KXS14381.1 - 0.26 9.5 8.8 0.32 9.2 8.8 1.0 1 0 0 1 1 1 0 CDC45-like protein Apt1 PF10351.9 KXS14381.1 - 3.5 6.4 5.9 4 6.2 5.9 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain SRP-alpha_N PF04086.13 KXS14381.1 - 7.7 6.3 10.8 9.7 6.0 10.8 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal RIO1 PF01163.22 KXS14382.1 - 5.6e-35 120.6 0.0 6.1e-35 120.5 0.0 1.0 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 KXS14382.1 - 0.028 13.2 0.0 0.033 13.0 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Pkinase PF00069.25 KXS14382.1 - 0.12 11.7 0.0 0.14 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain NAD_binding_10 PF13460.6 KXS14385.1 - 0.00072 19.5 0.0 0.0012 18.8 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KXS14385.1 - 0.00091 18.8 0.1 0.013 15.0 0.0 2.1 1 1 1 2 2 2 1 NmrA-like family Rossmann-like PF10727.9 KXS14385.1 - 0.0016 18.3 0.1 0.003 17.4 0.1 1.4 1 0 0 1 1 1 1 Rossmann-like domain F420_oxidored PF03807.17 KXS14385.1 - 0.031 14.9 0.0 0.056 14.0 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.21 KXS14385.1 - 0.034 13.6 0.0 0.052 13.0 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family HYR PF02494.16 KXS14385.1 - 0.094 13.1 1.0 4.6 7.7 0.1 3.1 3 1 0 3 3 3 0 HYR domain zf-met PF12874.7 KXS14385.1 - 0.15 12.5 0.3 0.29 11.6 0.3 1.5 1 0 0 1 1 1 0 Zinc-finger of C2H2 type EutH PF04346.12 KXS14385.1 - 0.2 10.8 0.0 0.27 10.4 0.0 1.1 1 0 0 1 1 1 0 Ethanolamine utilisation protein, EutH Zip PF02535.22 KXS14386.1 - 4.9e-50 170.6 6.1 6.5e-50 170.2 6.1 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter HupE_UreJ PF04955.12 KXS14386.1 - 0.042 13.3 5.0 0.022 14.2 1.9 2.1 2 0 0 2 2 2 0 HupE / UreJ protein FAD_binding_4 PF01565.23 KXS14387.1 - 7.7e-28 97.0 2.4 1.4e-27 96.1 2.4 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXS14387.1 - 9.7e-08 32.0 0.1 1.7e-07 31.2 0.1 1.4 1 0 0 1 1 1 1 Berberine and berberine like FNIP_C PF14638.6 KXS14389.1 - 0.094 12.3 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Folliculin-interacting protein C-terminus NIF PF03031.18 KXS14390.1 - 1.7e-55 187.1 0.1 1.9e-55 186.9 0.1 1.0 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD PF12710.7 KXS14390.1 - 0.062 13.7 0.4 0.6 10.5 0.0 2.0 1 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase Glyco_hydro_9 PF00759.19 KXS14391.1 - 1.3e-72 245.5 5.0 1.8e-72 245.0 5.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 Annexin PF00191.20 KXS14392.1 - 1.2e-22 79.8 0.6 1.5e-10 41.0 0.1 3.7 4 0 0 4 4 4 3 Annexin NIF PF03031.18 KXS14393.1 - 3.8e-52 176.2 0.0 5.1e-52 175.8 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Ribosomal_S7 PF00177.21 KXS14394.1 - 1.2e-26 93.1 0.6 1.4e-26 92.9 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e M-inducer_phosp PF06617.13 KXS14394.1 - 0.045 13.0 0.1 2.2 7.5 0.0 2.0 1 1 1 2 2 2 0 M-phase inducer phosphatase FYVE PF01363.21 KXS14395.1 - 4.2e-16 58.8 12.3 6.6e-16 58.2 12.3 1.3 1 0 0 1 1 1 1 FYVE zinc finger zf-AN1 PF01428.16 KXS14395.1 - 0.0057 16.8 5.1 0.0057 16.8 5.1 2.2 2 0 0 2 2 2 1 AN1-like Zinc finger IBR PF01485.21 KXS14395.1 - 0.51 10.6 8.9 0.052 13.8 3.6 2.0 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain Neurensin PF14927.6 KXS14397.1 - 0.1 12.3 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Neurensin Podoplanin PF05808.11 KXS14397.1 - 0.76 9.9 7.7 4.5 7.3 7.8 2.2 1 1 1 2 2 2 0 Podoplanin MtrF PF09472.10 KXS14397.1 - 1.9 7.9 5.5 3.8 7.0 5.5 1.5 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) DNA_pol_A_exo1 PF01612.20 KXS14398.1 - 2.6e-38 131.5 0.1 3.4e-38 131.1 0.1 1.1 1 0 0 1 1 1 1 3'-5' exonuclease FAST_2 PF08368.12 KXS14398.1 - 0.028 15.2 0.0 0.28 12.0 0.0 2.2 2 0 0 2 2 2 0 FAST kinase-like protein, subdomain 2 SIR2 PF02146.17 KXS14399.1 - 2e-53 180.9 0.0 1.6e-34 119.4 0.0 2.2 2 0 0 2 2 2 2 Sir2 family Pkinase PF00069.25 KXS14400.1 - 6.3e-52 176.6 0.0 8.3e-52 176.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS14400.1 - 2.1e-24 86.2 0.0 3e-24 85.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXS14400.1 - 9.3e-06 25.7 0.0 0.0004 20.4 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KXS14400.1 - 0.00022 20.7 0.1 0.00037 19.9 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KXS14400.1 - 0.0015 18.2 0.0 0.0029 17.2 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 KXS14400.1 - 0.0019 17.0 0.0 0.0019 17.0 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 KXS14400.1 - 0.0028 17.0 0.0 0.0066 15.8 0.0 1.5 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 KXS14400.1 - 0.17 11.5 0.0 0.53 9.9 0.0 1.7 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 TPR_14 PF13428.6 KXS14400.1 - 0.28 12.1 1.2 22 6.2 0.2 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Chitin_synth_2 PF03142.15 KXS14401.1 - 1.1e-230 766.8 0.0 1.5e-230 766.3 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_tranf_2_3 PF13641.6 KXS14401.1 - 2.5e-14 53.7 0.2 1.1e-13 51.7 0.1 2.0 3 0 0 3 3 3 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 KXS14401.1 - 3.6e-11 43.3 9.4 3.6e-11 43.3 9.4 2.2 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 KXS14401.1 - 0.00047 19.7 0.1 0.41 10.1 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 21 DUF4579 PF15158.6 KXS14401.1 - 0.26 11.0 1.8 0.52 10.0 1.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4579) EF-hand_1 PF00036.32 KXS14402.1 - 1.9e-26 89.6 13.5 6.3e-07 28.5 0.4 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KXS14402.1 - 3.3e-23 81.9 7.2 1e-13 51.5 1.1 2.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KXS14402.1 - 8.9e-21 72.0 8.0 4.8e-05 23.0 0.0 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KXS14402.1 - 3.7e-19 67.3 14.2 1.3e-06 27.6 0.3 4.5 4 1 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 KXS14402.1 - 7.6e-16 57.7 13.8 1e-05 25.3 1.0 4.3 2 2 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KXS14402.1 - 3.3e-08 33.9 0.0 0.0026 18.0 0.0 2.3 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KXS14402.1 - 1e-05 25.4 6.8 0.0083 16.1 0.3 3.9 1 1 3 4 4 4 1 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 KXS14402.1 - 0.0011 19.2 0.3 1.6 9.1 0.0 3.1 2 1 1 3 3 3 1 EF-hand domain Sigma54_CBD PF04963.13 KXS14402.1 - 0.025 14.5 0.1 0.26 11.1 0.0 2.2 1 1 1 2 2 2 0 Sigma-54 factor, core binding domain Dockerin_1 PF00404.18 KXS14402.1 - 0.028 14.6 5.3 0.24 11.6 1.6 3.1 1 1 3 4 4 4 0 Dockerin type I domain CHCH PF06747.13 KXS14403.1 - 0.0025 17.9 0.4 0.0049 17.0 0.4 1.5 1 0 0 1 1 1 1 CHCH domain DnaJ PF00226.31 KXS14404.1 - 4.1e-10 39.7 0.0 7.7e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain B12D PF06522.11 KXS14406.1 - 0.049 13.4 0.1 0.065 13.0 0.1 1.2 1 0 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit Arb2 PF09757.9 KXS14407.1 - 3.5e-05 23.1 0.0 4.7e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Arb2 domain Hydrolase_4 PF12146.8 KXS14407.1 - 0.0019 17.5 0.0 0.0025 17.1 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 P5CR_dimer PF14748.6 KXS14410.1 - 1.8e-36 124.5 1.2 1.8e-36 124.5 1.2 1.8 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 KXS14410.1 - 5.8e-14 52.4 0.1 1.7e-13 50.9 0.1 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 KXS14410.1 - 0.14 12.2 0.0 0.44 10.6 0.0 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Glyco_hydro_15 PF00723.21 KXS14411.1 - 1.5e-124 416.2 0.0 1.9e-124 415.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 ILEI PF15711.5 KXS14411.1 - 2.5e-15 56.7 0.0 8.3e-15 55.0 0.0 2.0 1 0 0 1 1 1 1 Interleukin-like EMT inducer Milton PF12448.8 KXS14411.1 - 0.16 12.0 0.7 0.38 10.9 0.7 1.5 1 0 0 1 1 1 0 Kinesin associated protein DUF4366 PF14283.6 KXS14412.1 - 0.026 14.5 0.6 0.046 13.8 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) DUF4746 PF15928.5 KXS14412.1 - 0.031 13.7 0.8 0.055 12.9 0.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) GEN1_C PF18380.1 KXS14412.1 - 0.095 13.6 2.6 0.2 12.6 2.6 1.4 1 0 0 1 1 1 0 Holliday junction resolvase Gen1 C-terminal domain Sec3_C PF09763.9 KXS14412.1 - 0.1 11.0 3.8 0.13 10.6 3.8 1.0 1 0 0 1 1 1 0 Exocyst complex component Sec3 FAM176 PF14851.6 KXS14412.1 - 0.11 12.1 5.1 0.2 11.3 5.1 1.4 1 0 0 1 1 1 0 FAM176 family Folate_carrier PF01770.18 KXS14412.1 - 0.2 10.4 0.4 0.28 9.9 0.4 1.1 1 0 0 1 1 1 0 Reduced folate carrier DUF3112 PF11309.8 KXS14412.1 - 0.26 10.7 0.4 0.44 9.9 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3112) DUF3464 PF11947.8 KXS14412.1 - 0.27 11.0 3.7 0.56 10.0 3.7 1.5 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 SpoIIIAH PF12685.7 KXS14412.1 - 0.47 10.3 7.8 0.64 9.8 7.8 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein PPL5 PF18168.1 KXS14412.1 - 0.57 9.4 3.1 0.74 9.1 3.1 1.3 1 0 0 1 1 1 0 Prim-pol family 5 NPR3 PF03666.13 KXS14412.1 - 0.78 8.5 3.7 0.91 8.2 3.7 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 RPN2_C PF18004.1 KXS14412.1 - 1 9.2 8.7 2 8.3 8.7 1.4 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain F-box PF00646.33 KXS14413.1 - 4.1e-06 26.5 0.1 4.1e-06 26.5 0.1 2.1 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KXS14413.1 - 4.3e-05 23.3 0.1 4.3e-05 23.3 0.1 3.2 3 0 0 3 3 3 1 F-box-like F-box_4 PF15966.5 KXS14413.1 - 0.00015 21.6 1.2 0.00023 21.0 0.0 1.8 2 0 0 2 2 2 1 F-box OMPdecase PF00215.24 KXS14415.1 - 2.4e-68 230.1 0.0 3.3e-68 229.7 0.0 1.1 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family RCDG1 PF15725.5 KXS14415.1 - 0.058 13.8 2.2 0.11 12.9 2.2 1.4 1 0 0 1 1 1 0 Renal cancer differentiation gene 1 protein zf-C2H2 PF00096.26 KXS14416.1 - 2.1e-14 53.1 7.7 4.8e-05 23.6 0.4 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXS14416.1 - 8e-12 44.9 4.9 0.0036 18.0 0.4 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KXS14416.1 - 1.5e-07 31.5 4.7 0.00028 21.2 0.8 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-BED PF02892.15 KXS14416.1 - 1.4e-06 28.2 6.1 0.0078 16.2 0.1 3.3 1 1 2 3 3 3 3 BED zinc finger zf-Di19 PF05605.12 KXS14416.1 - 6.7e-05 23.1 0.4 0.3 11.4 0.1 2.6 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 KXS14416.1 - 0.00029 21.1 4.4 0.2 12.1 0.1 3.3 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-CHCC PF10276.9 KXS14416.1 - 0.0012 18.8 1.3 3.3 7.9 0.2 3.2 3 0 0 3 3 3 2 Zinc-finger domain PyrI_C PF02748.15 KXS14416.1 - 0.0016 18.3 3.2 1 9.3 0.1 2.6 2 1 0 2 2 2 2 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_jaz PF12171.8 KXS14416.1 - 0.0043 17.3 5.0 1.5 9.2 0.3 3.4 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 KXS14416.1 - 0.0053 16.5 5.5 3.3 7.6 0.2 3.4 3 0 0 3 3 3 1 zinc-finger C2H2-type zf-C2H2_8 PF15909.5 KXS14416.1 - 0.0092 16.3 0.3 0.022 15.0 0.3 1.7 1 0 0 1 1 1 1 C2H2-type zinc ribbon zf-C2HC_2 PF13913.6 KXS14416.1 - 0.025 14.5 9.1 1.2 9.1 0.2 3.8 3 1 0 3 3 3 0 zinc-finger of a C2HC-type C1_1 PF00130.22 KXS14416.1 - 0.047 13.6 2.3 0.46 10.4 0.5 2.4 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-FCS PF06467.14 KXS14416.1 - 0.051 13.5 4.3 3.5 7.6 0.2 3.0 3 0 0 3 3 3 0 MYM-type Zinc finger with FCS sequence motif Prok-RING_1 PF14446.6 KXS14416.1 - 0.062 13.2 2.1 19 5.3 0.0 3.2 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 zf-C2HE PF16278.5 KXS14416.1 - 0.088 13.3 5.1 13 6.3 0.3 3.3 1 1 2 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger Zn-ribbon_8 PF09723.10 KXS14416.1 - 0.1 12.7 4.6 2.8 8.1 0.9 3.0 2 1 1 3 3 3 0 Zinc ribbon domain zf_UBZ PF18439.1 KXS14416.1 - 0.13 11.9 3.0 7.3 6.3 0.1 3.2 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-C2H2_2 PF12756.7 KXS14416.1 - 0.13 12.6 3.9 11 6.4 0.1 3.0 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2H2_3rep PF18868.1 KXS14416.1 - 0.18 12.4 6.1 15 6.2 0.2 3.5 1 1 2 3 3 3 0 Zinc finger C2H2-type, 3 repeats FYVE PF01363.21 KXS14416.1 - 0.19 11.9 5.5 0.52 10.5 5.5 1.8 1 1 0 1 1 1 0 FYVE zinc finger zf-C2H2_6 PF13912.6 KXS14416.1 - 0.26 11.3 6.0 8.3 6.5 0.6 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger C1_2 PF03107.16 KXS14416.1 - 0.26 11.6 6.6 4.5 7.7 0.2 3.2 1 1 2 3 3 3 0 C1 domain OrfB_Zn_ribbon PF07282.11 KXS14416.1 - 0.55 10.2 4.5 4.9 7.1 1.3 2.7 1 1 2 3 3 3 0 Putative transposase DNA-binding domain zf-ribbon_3 PF13248.6 KXS14416.1 - 0.73 9.3 2.8 21 4.7 0.2 3.1 3 0 0 3 3 3 0 zinc-ribbon domain Sgf11 PF08209.11 KXS14416.1 - 0.86 9.2 5.0 15 5.3 0.2 3.0 3 0 0 3 3 3 0 Sgf11 (transcriptional regulation protein) DZR PF12773.7 KXS14416.1 - 1.2 9.2 4.8 41 4.3 4.8 2.6 1 1 0 1 1 1 0 Double zinc ribbon EXS PF03124.14 KXS14418.1 - 1.8e-65 221.5 5.1 2.7e-65 220.9 5.1 1.2 1 0 0 1 1 1 1 EXS family Cons_hypoth698 PF03601.14 KXS14418.1 - 0.019 13.9 0.5 4.6 6.0 0.1 2.3 2 0 0 2 2 2 0 Conserved hypothetical protein 698 APC_u9 PF16633.5 KXS14418.1 - 0.17 13.0 0.8 0.33 12.1 0.8 1.4 1 0 0 1 1 1 0 Unstructured region on APC between 1st two creatine-rich regions zf-C2H2 PF00096.26 KXS14421.1 - 0.012 16.0 3.2 0.012 16.0 3.2 3.1 3 0 0 3 3 3 0 Zinc finger, C2H2 type Pox_D2 PF04701.13 KXS14422.1 - 0.085 13.0 0.0 0.09 13.0 0.0 1.0 1 0 0 1 1 1 0 Pox virus D2 protein Glyoxalase PF00903.25 KXS14424.1 - 1.6e-11 44.5 0.0 1e-08 35.4 0.0 3.0 2 2 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 KXS14424.1 - 2.2e-09 38.1 0.0 1.7e-05 25.5 0.0 2.4 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_4 PF13669.6 KXS14424.1 - 0.0013 19.0 0.0 0.051 13.9 0.0 2.6 2 1 1 3 3 3 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Bombolitin PF08096.11 KXS14424.1 - 0.074 13.3 0.1 0.21 11.9 0.1 1.8 1 0 0 1 1 1 0 Bombolitin family BRCT_2 PF16589.5 KXS14424.1 - 0.18 12.2 0.0 5.2 7.6 0.0 2.3 2 0 0 2 2 2 0 BRCT domain, a BRCA1 C-terminus domain Pept_tRNA_hydro PF01195.19 KXS14425.1 - 1.4e-42 145.6 0.0 1.6e-42 145.4 0.0 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase B3_4 PF03483.17 KXS14425.1 - 0.11 12.1 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 B3/4 domain Myb_DNA-binding PF00249.31 KXS14426.1 - 1.3e-13 50.9 0.2 1.7e-10 40.9 0.1 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KXS14426.1 - 3.1e-10 40.2 0.7 5.7e-08 32.9 0.0 2.5 3 0 0 3 3 3 2 Myb-like DNA-binding domain APC_u13 PF16634.5 KXS14426.1 - 0.075 12.9 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 Unstructured region on APC between APC_crr and SAMP LRR_4 PF12799.7 KXS14427.1 - 2.3e-05 24.7 0.0 5.3 7.6 0.0 4.3 4 1 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KXS14427.1 - 6.6e-05 22.7 1.4 0.36 11.0 0.0 4.2 4 0 0 4 4 4 2 Leucine Rich repeat LRR_1 PF00560.33 KXS14427.1 - 0.0022 18.3 0.2 12 6.9 0.0 4.5 4 1 1 5 5 5 1 Leucine Rich Repeat RTC PF01137.21 KXS14428.1 - 2.4e-52 177.3 0.0 2.8e-52 177.1 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 KXS14428.1 - 8.5e-31 106.5 0.0 1.9e-30 105.4 0.0 1.6 1 1 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain Ashwin PF15323.6 KXS14428.1 - 0.82 9.6 5.6 1.3 9.0 5.6 1.2 1 0 0 1 1 1 0 Developmental protein Ribonuc_red_lgC PF02867.15 KXS14429.1 - 3.2e-188 626.5 0.0 4e-188 626.2 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 KXS14429.1 - 1.1e-21 76.6 0.0 2.5e-21 75.5 0.0 1.6 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 KXS14429.1 - 5.2e-16 59.0 0.0 2.1e-15 57.1 0.0 2.1 2 0 0 2 2 2 1 ATP cone domain Ribonuc_red_sm PF00268.21 KXS14430.1 - 2.7e-91 305.9 0.1 3.2e-91 305.7 0.1 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Abhydrolase_1 PF00561.20 KXS14431.1 - 2.8e-24 86.2 0.0 1.4e-23 83.8 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXS14431.1 - 3.4e-15 57.2 1.4 4.4e-15 56.9 1.4 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXS14431.1 - 0.0071 15.6 0.1 0.011 15.0 0.1 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Frag1 PF10277.9 KXS14432.1 - 6.3e-33 114.2 12.3 6.9e-33 114.0 12.3 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family MnhB PF04039.13 KXS14432.1 - 0.14 12.5 5.0 0.61 10.4 1.7 2.5 1 1 2 3 3 3 0 Domain related to MnhB subunit of Na+/H+ antiporter DUF4181 PF13789.6 KXS14432.1 - 0.4 11.0 9.3 4.6 7.5 0.1 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4181) 7tm_1 PF00001.21 KXS14432.1 - 0.8 9.0 8.0 1.9 7.7 6.4 2.2 1 1 1 2 2 2 0 7 transmembrane receptor (rhodopsin family) DUF485 PF04341.12 KXS14432.1 - 0.89 9.5 14.3 0.85 9.6 0.2 3.4 4 0 0 4 4 4 0 Protein of unknown function, DUF485 DUF2070 PF09843.9 KXS14432.1 - 4.4 5.5 9.3 5.6 5.1 8.6 1.5 1 1 1 2 2 2 0 Predicted membrane protein (DUF2070) CMAS PF02353.20 KXS14433.1 - 1.6e-56 191.6 0.4 2e-56 191.3 0.4 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 KXS14433.1 - 3.6e-10 40.4 0.0 8.2e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXS14433.1 - 1.6e-09 38.3 0.0 4.3e-09 36.9 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXS14433.1 - 1.9e-08 34.4 0.0 4.4e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXS14433.1 - 8.4e-08 32.9 0.0 3.1e-07 31.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXS14433.1 - 1.2e-06 28.5 0.0 7e-06 25.9 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain MTS PF05175.14 KXS14433.1 - 0.012 15.2 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_4 PF02390.17 KXS14433.1 - 0.026 14.0 0.0 0.081 12.4 0.0 1.8 2 0 0 2 2 2 0 Putative methyltransferase DOT1 PF08123.13 KXS14433.1 - 0.03 13.8 0.0 0.05 13.1 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 HTH_24 PF13412.6 KXS14433.1 - 0.16 11.6 0.0 23 4.6 0.0 3.3 4 0 0 4 4 4 0 Winged helix-turn-helix DNA-binding PrmA PF06325.13 KXS14433.1 - 0.16 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) FCH PF00611.23 KXS14434.1 - 9.5e-05 22.6 0.7 0.00052 20.2 0.4 2.3 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain BAR_3 PF16746.5 KXS14434.1 - 0.00023 21.0 2.5 0.00044 20.0 2.5 1.4 1 0 0 1 1 1 1 BAR domain of APPL family SPATA19 PF15212.6 KXS14434.1 - 0.022 14.9 0.9 0.11 12.7 0.1 2.4 2 0 0 2 2 2 0 Spermatogenesis-associated protein 19, mitochondrial Vps5 PF09325.10 KXS14434.1 - 0.025 14.1 6.5 0.034 13.7 0.7 3.1 3 0 0 3 3 3 0 Vps5 C terminal like DUF4061 PF13270.6 KXS14434.1 - 0.054 13.8 0.1 0.18 12.1 0.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4061) Fez1 PF06818.15 KXS14434.1 - 0.25 11.8 3.2 0.34 11.3 1.3 2.2 1 1 0 1 1 1 0 Fez1 FAM184 PF15665.5 KXS14434.1 - 8.4 6.1 9.8 0.71 9.6 4.6 1.8 2 0 0 2 2 2 0 Family with sequence similarity 184, A and B MAD PF05557.13 KXS14435.1 - 0.0087 14.5 13.8 0.011 14.2 13.8 1.0 1 0 0 1 1 1 1 Mitotic checkpoint protein Bacillus_HBL PF05791.11 KXS14435.1 - 0.088 12.6 2.3 0.12 12.2 2.3 1.1 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) DUF2807 PF10988.8 KXS14435.1 - 0.099 12.4 0.1 0.99 9.2 0.0 1.9 1 1 1 2 2 2 0 Putative auto-transporter adhesin, head GIN domain Spc29 PF17082.5 KXS14435.1 - 0.15 11.9 2.5 0.11 12.3 0.6 1.6 1 1 1 2 2 2 0 Spindle Pole Component 29 DUF1676 PF07898.13 KXS14435.1 - 0.43 10.6 5.2 0.62 10.1 5.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) Spc7 PF08317.11 KXS14435.1 - 1 8.2 14.6 1.5 7.6 14.6 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein FPP PF05911.11 KXS14435.1 - 1.9 6.6 15.0 3.9 5.5 15.0 1.4 1 1 0 1 1 1 0 Filament-like plant protein, long coiled-coil Exonuc_VII_L PF02601.15 KXS14435.1 - 2.1 7.9 7.0 2.5 7.6 7.0 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit TMCO5 PF14992.6 KXS14435.1 - 2.1 7.8 14.5 3 7.4 14.5 1.1 1 0 0 1 1 1 0 TMCO5 family DUF2730 PF10805.8 KXS14435.1 - 3.3 7.8 6.8 1.1 9.4 2.6 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF2730) UPF0139 PF03669.13 KXS14436.1 - 0.0003 20.6 0.6 0.00044 20.1 0.6 1.3 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0139) DUF2798 PF11391.8 KXS14436.1 - 3.8 7.6 9.4 0.96 9.5 3.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2798) EF-hand_7 PF13499.6 KXS14437.1 - 2.2e-10 40.8 0.2 2.9e-10 40.4 0.2 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 KXS14437.1 - 1.3e-09 36.9 2.7 0.00031 20.1 0.0 2.5 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 KXS14437.1 - 6.4e-08 31.9 0.1 0.0026 17.6 0.0 2.4 2 1 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 KXS14437.1 - 1.6e-07 30.5 0.8 0.00031 20.1 0.1 2.4 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 KXS14437.1 - 4.5e-06 26.4 0.4 0.016 15.0 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_4 PF12763.7 KXS14437.1 - 0.0016 18.3 0.8 0.0039 17.1 0.4 1.6 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 KXS14437.1 - 0.047 14.0 0.1 0.07 13.5 0.1 1.3 1 0 0 1 1 1 0 EF-hand domain sCache_like PF16736.5 KXS14437.1 - 0.063 13.4 0.1 0.077 13.1 0.1 1.2 1 0 0 1 1 1 0 Single Cache-like MMgT PF10270.9 KXS14437.1 - 0.14 12.6 0.0 0.16 12.4 0.0 1.1 1 0 0 1 1 1 0 Membrane magnesium transporter DUF4291 PF14124.6 KXS14439.1 - 6e-52 176.1 0.0 9.4e-52 175.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4291) Ham1p_like PF01725.16 KXS14441.1 - 5e-53 179.8 0.0 5.7e-53 179.6 0.0 1.0 1 0 0 1 1 1 1 Ham1 family Sporozoite_P67 PF05642.11 KXS14442.1 - 0.0086 14.2 0.0 0.0097 14.0 0.0 1.0 1 0 0 1 1 1 1 Sporozoite P67 surface antigen His_Phos_1 PF00300.22 KXS14443.1 - 1.8e-26 93.1 0.0 2.2e-26 92.8 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.22 KXS14443.1 - 0.11 11.9 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) LssY_C PF14067.6 KXS14443.1 - 0.13 11.7 0.1 0.2 11.2 0.1 1.2 1 0 0 1 1 1 0 LssY C-terminus Cpn60_TCP1 PF00118.24 KXS14444.1 - 1.4e-166 554.9 2.9 1.7e-166 554.7 2.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Tim44 PF04280.15 KXS14445.1 - 0.065 13.3 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Tim44-like domain Myb_DNA-bind_3 PF12776.7 KXS14446.1 - 1e-12 48.9 1.1 1.5e-12 48.3 0.3 1.7 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain DDE_Tnp_4 PF13359.6 KXS14447.1 - 8.5e-11 41.8 0.0 9.3e-11 41.6 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 KXS14447.1 - 0.0067 16.1 0.0 0.0074 15.9 0.0 1.1 1 0 0 1 1 1 1 Transposase DDE domain SH3_9 PF14604.6 KXS14449.1 - 4.1e-07 29.8 0.1 8.7e-07 28.7 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXS14449.1 - 8.6e-05 22.1 0.0 0.00014 21.4 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_16 PF18348.1 KXS14449.1 - 0.0063 16.3 0.0 0.015 15.1 0.0 1.6 1 0 0 1 1 1 1 Bacterial dipeptidyl-peptidase Sh3 domain Acyltransferase PF01553.21 KXS14451.1 - 1.4e-20 73.3 0.0 2e-20 72.8 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Trypsin PF00089.26 KXS14452.1 - 5e-34 118.0 6.0 7.4e-34 117.5 6.0 1.3 1 0 0 1 1 1 1 Trypsin PAN_1 PF00024.26 KXS14452.1 - 0.00011 22.1 1.4 0.00056 19.8 0.3 2.5 2 0 0 2 2 2 1 PAN domain PAN_3 PF08277.12 KXS14452.1 - 0.3 10.9 4.8 0.28 11.0 1.8 2.5 2 0 0 2 2 2 0 PAN-like domain PhyH PF05721.13 KXS14453.1 - 1.8e-29 103.5 0.1 2.4e-29 103.1 0.1 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 KXS14453.1 - 0.0032 17.9 0.0 1.2 9.6 0.0 2.3 1 1 1 2 2 2 2 Putative 2OG-Fe(II) oxygenase SEP PF08059.13 KXS14453.1 - 0.15 12.7 0.0 1.7 9.3 0.0 2.2 2 0 0 2 2 2 0 SEP domain Peptidase_M3 PF01432.20 KXS14454.1 - 3.1e-152 508.0 0.0 4e-152 507.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 GLTP PF08718.11 KXS14455.1 - 7.1e-14 52.3 0.0 1.1e-13 51.7 0.0 1.3 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) PHF5 PF03660.14 KXS14456.1 - 4.7e-50 168.1 9.7 5.3e-50 168.0 9.7 1.0 1 0 0 1 1 1 1 PHF5-like protein PolC_DP2 PF03833.13 KXS14456.1 - 0.0021 16.0 4.0 0.0022 16.0 4.0 1.0 1 0 0 1 1 1 1 DNA polymerase II large subunit DP2 C1_2 PF03107.16 KXS14456.1 - 0.26 11.7 14.6 0.18 12.1 2.2 2.4 1 1 1 2 2 2 0 C1 domain DZR PF12773.7 KXS14456.1 - 0.53 10.3 10.5 2.4 8.2 9.3 2.3 1 1 1 2 2 2 0 Double zinc ribbon Amino_oxidase PF01593.24 KXS14457.1 - 3e-49 168.6 0.1 3.6e-49 168.3 0.1 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KXS14457.1 - 4.6e-09 36.4 0.0 9.9e-09 35.3 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KXS14457.1 - 0.025 14.6 0.2 1.5 8.8 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding DAO PF01266.24 KXS14457.1 - 0.034 13.7 0.6 0.15 11.6 0.1 2.2 3 0 0 3 3 3 0 FAD dependent oxidoreductase BTG PF07742.12 KXS14458.1 - 7.8e-25 87.0 0.0 2.5e-24 85.4 0.0 1.7 1 1 0 1 1 1 1 BTG family MFS_1 PF07690.16 KXS14460.1 - 1e-22 80.6 13.8 5.3e-15 55.2 1.7 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXS14460.1 - 0.14 11.0 0.0 0.14 11.0 0.0 1.9 3 0 0 3 3 3 0 Sugar (and other) transporter Pkinase PF00069.25 KXS14462.1 - 6.4e-36 124.1 0.0 1.4e-24 86.9 0.0 2.1 1 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXS14462.1 - 1.1e-15 57.7 0.0 1.4e-08 34.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase WW PF00397.26 KXS14464.1 - 8.1e-11 41.8 3.0 1.3e-10 41.1 3.0 1.4 1 0 0 1 1 1 1 WW domain 2-oxogl_dehyd_N PF16078.5 KXS14464.1 - 0.024 14.2 0.8 0.037 13.6 0.8 1.3 1 0 0 1 1 1 0 2-oxoglutarate dehydrogenase N-terminus Pkinase PF00069.25 KXS14465.1 - 8.4e-35 120.4 0.0 1.1e-34 120.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS14465.1 - 4.2e-13 49.2 0.0 6.1e-13 48.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KXS14465.1 - 9.8e-05 21.5 0.0 0.00014 21.0 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KXS14465.1 - 0.00028 20.9 0.3 0.0039 17.1 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KXS14465.1 - 0.00043 19.7 0.0 0.00069 19.0 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KXS14465.1 - 0.013 15.1 0.9 0.043 13.4 0.0 2.0 2 0 0 2 2 2 0 Choline/ethanolamine kinase MBOAT PF03062.19 KXS14466.1 - 1.3e-34 120.1 5.4 1.3e-34 120.1 5.4 2.6 2 1 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family Pkinase PF00069.25 KXS14467.1 - 3.6e-45 154.4 0.0 4.8e-45 154.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS14467.1 - 1.5e-21 76.9 0.0 2e-21 76.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KXS14467.1 - 4.6e-05 22.9 0.3 6.7e-05 22.3 0.3 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KXS14467.1 - 7e-05 21.9 0.2 0.0001 21.4 0.2 1.1 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KXS14467.1 - 0.00022 21.3 0.6 0.00055 19.9 0.1 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KXS14467.1 - 0.00027 20.3 0.0 0.00043 19.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KXS14467.1 - 0.091 11.5 0.0 0.13 11.0 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Fic_N PF13784.6 KXS14468.1 - 0.12 12.5 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Fic/DOC family N-terminal Luciferase_N PF05295.11 KXS14469.1 - 0.18 11.8 0.0 0.33 11.0 0.0 1.4 1 0 0 1 1 1 0 Luciferase/LBP N-terminal domain EP400_N PF15790.5 KXS14470.1 - 0.00056 18.9 1.2 0.00056 18.9 1.2 2.0 2 0 0 2 2 2 1 E1A-binding protein p400, N-terminal Bactofilin PF04519.13 KXS14471.1 - 0.13 12.6 4.0 0.38 11.1 4.0 1.7 1 0 0 1 1 1 0 Polymer-forming cytoskeletal Pkinase PF00069.25 KXS14473.1 - 3.2e-43 148.0 0.0 4.3e-43 147.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS14473.1 - 5.9e-21 74.9 0.0 8.4e-21 74.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXS14473.1 - 1.4e-06 28.4 0.8 0.00011 22.3 0.2 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KXS14473.1 - 0.0011 18.1 0.1 0.0015 17.6 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 KXS14473.1 - 0.0023 16.8 0.5 0.0031 16.3 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 KXS14473.1 - 0.0043 16.4 0.1 0.01 15.2 0.1 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KXS14473.1 - 0.051 12.9 0.0 0.16 11.2 0.0 1.7 2 0 0 2 2 2 0 Kinase-like DSPc PF00782.20 KXS14474.1 - 2.8e-14 53.1 0.0 1.7e-13 50.6 0.1 1.9 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain CysG_dimeriser PF10414.9 KXS14474.1 - 0.031 14.0 0.1 0.087 12.6 0.1 1.7 1 0 0 1 1 1 0 Sirohaem synthase dimerisation region Collagen PF01391.18 KXS14474.1 - 0.074 12.8 8.9 0.12 12.1 8.9 1.3 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) DSPc PF00782.20 KXS14475.1 - 4.9e-15 55.5 0.0 1.8e-14 53.7 0.0 1.7 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 KXS14475.1 - 0.13 12.6 0.0 0.3 11.4 0.0 1.7 1 1 0 1 1 1 0 Rit1 DUSP-like domain Y_phosphatase PF00102.27 KXS14475.1 - 0.2 11.2 0.0 0.28 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase GCR1_C PF12550.8 KXS14476.1 - 3.7e-14 52.8 0.0 4.2e-14 52.6 0.0 1.0 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes Glyco_transf_54 PF04666.13 KXS14477.1 - 0.00018 20.4 0.0 0.026 13.4 0.0 2.6 3 0 0 3 3 3 2 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region MMR_HSR1_Xtn PF16897.5 KXS14478.1 - 3e-38 130.1 0.3 6.6e-38 129.0 0.3 1.6 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 KXS14478.1 - 8.1e-22 77.0 0.0 1.6e-21 76.1 0.0 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 KXS14478.1 - 5.4e-19 68.4 0.0 1.1e-18 67.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KXS14478.1 - 1e-08 34.9 0.0 1.7e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KXS14478.1 - 0.00073 19.6 0.2 0.25 11.4 0.0 2.3 1 1 0 2 2 2 2 Dynamin family MeaB PF03308.16 KXS14478.1 - 0.03 13.3 0.2 0.094 11.7 0.0 1.9 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NB-ARC PF00931.22 KXS14478.1 - 0.034 13.3 0.0 0.062 12.5 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain MCM PF00493.23 KXS14478.1 - 0.096 11.8 0.0 0.2 10.7 0.0 1.5 1 0 0 1 1 1 0 MCM P-loop domain adh_short_C2 PF13561.6 KXS14479.1 - 1.3e-62 211.4 0.6 1.6e-62 211.1 0.6 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXS14479.1 - 3e-54 183.4 1.1 3.7e-54 183.2 1.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXS14479.1 - 1.8e-06 28.0 2.2 3.8e-06 26.9 2.2 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KXS14479.1 - 0.01 15.3 0.2 0.023 14.2 0.2 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 KXS14479.1 - 0.011 15.0 0.1 0.022 14.1 0.1 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF3679 PF12438.8 KXS14481.1 - 0.0028 17.3 0.9 0.0055 16.4 0.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3679) DUF4330 PF14221.6 KXS14481.1 - 0.019 15.2 0.0 0.029 14.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4330) DUF687 PF05095.12 KXS14481.1 - 0.052 12.0 0.4 0.084 11.4 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF687) Glyco_hydro_47 PF01532.20 KXS14482.1 - 2.8e-117 392.4 0.0 3.7e-117 392.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 PHD PF00628.29 KXS14483.1 - 0.00041 20.2 1.0 0.00086 19.2 1.0 1.5 1 0 0 1 1 1 1 PHD-finger DUF35_N PF12172.8 KXS14483.1 - 0.03 14.2 0.8 0.14 12.0 0.8 2.2 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) DUF1488 PF07369.11 KXS14483.1 - 0.076 13.0 1.3 0.16 12.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1488) adh_short_C2 PF13561.6 KXS14484.1 - 3.9e-28 98.6 1.7 6.3e-26 91.4 1.7 2.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXS14484.1 - 6.2e-25 87.8 3.5 1.2e-22 80.3 3.5 2.9 1 1 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 KXS14484.1 - 0.012 15.1 0.1 0.023 14.2 0.1 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family F-box-like PF12937.7 KXS14485.1 - 0.0029 17.4 0.2 0.0066 16.3 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXS14485.1 - 0.0055 16.5 0.7 0.011 15.6 0.7 1.4 1 0 0 1 1 1 1 F-box domain Adap_comp_sub PF00928.21 KXS14486.1 - 1.5e-80 270.3 0.0 1.9e-80 270.0 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KXS14486.1 - 7.3e-07 29.2 0.2 1.2e-06 28.6 0.2 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF2973 PF11189.8 KXS14488.1 - 0.033 14.3 0.2 0.098 12.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2973) FUSC-like PF12805.7 KXS14488.1 - 0.039 13.0 5.1 0.068 12.2 5.1 1.4 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS DUF3488 PF11992.8 KXS14488.1 - 3 6.7 10.4 2.2 7.1 1.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3488) DUF3328 PF11807.8 KXS14490.1 - 0.2 11.4 0.0 0.45 10.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) 7tm_1 PF00001.21 KXS14492.1 - 4.3e-13 49.2 7.6 5.9e-13 48.7 7.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) TetR_C_28 PF17937.1 KXS14492.1 - 0.15 12.5 0.4 0.45 11.0 0.1 1.9 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Cytochrom_B_C PF00032.17 KXS14492.1 - 4.9 7.5 6.4 1.6 9.0 0.9 2.7 2 1 1 3 3 3 0 Cytochrome b(C-terminal)/b6/petD Exo_endo_phos PF03372.23 KXS14493.1 - 2.1e-11 43.8 0.0 5.9e-11 42.3 0.0 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family HlyIII PF03006.20 KXS14494.1 - 1.2e-56 192.0 23.6 1.4e-56 191.7 23.6 1.1 1 0 0 1 1 1 1 Haemolysin-III related TrbE PF11100.8 KXS14494.1 - 2.8 8.2 6.7 0.47 10.7 0.2 2.8 3 0 0 3 3 3 0 Conjugal transfer protein TrbE NADHdh-2_N PF12155.8 KXS14494.1 - 3 8.3 6.3 1.3 9.5 0.3 2.9 3 0 0 3 3 3 0 NADH dehydrogenase subunit 2 N-terminal Cyclin_N PF00134.23 KXS14495.1 - 9.2e-26 90.1 0.2 1.5e-25 89.3 0.2 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KXS14495.1 - 1.5e-06 28.3 1.2 0.00045 20.3 0.2 2.3 2 0 0 2 2 2 2 Cyclin, C-terminal domain SKG6 PF08693.10 KXS14496.1 - 0.14 11.6 2.7 0.27 10.7 2.7 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Amnionless PF14828.6 KXS14496.1 - 0.19 10.5 0.0 2.9 6.6 0.0 2.1 2 0 0 2 2 2 0 Amnionless PhnA_Zn_Ribbon PF08274.12 KXS14497.1 - 0.14 12.1 0.0 0.27 11.2 0.0 1.6 1 1 0 1 1 1 0 PhnA Zinc-Ribbon zf_CopZ PF18423.1 KXS14497.1 - 0.52 10.3 2.5 0.81 9.7 0.9 1.9 1 1 1 2 2 2 0 Zinc binding domain Ank_4 PF13637.6 KXS14498.1 - 9.5e-19 67.5 5.4 8e-06 26.3 0.1 2.9 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXS14498.1 - 9.3e-18 62.5 0.3 0.0039 17.6 0.0 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_2 PF12796.7 KXS14498.1 - 1.2e-16 61.1 0.0 7.9e-12 45.6 0.0 2.1 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXS14498.1 - 5.4e-15 55.3 5.2 1.7e-06 28.2 0.1 3.9 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 KXS14498.1 - 1.8e-09 37.6 1.1 0.18 12.3 0.0 4.1 3 1 1 4 4 4 4 Ankyrin repeat MatE PF01554.18 KXS14500.1 - 9.4e-50 168.4 19.8 3.3e-28 98.4 9.1 3.4 2 1 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 KXS14500.1 - 3.5e-09 36.9 5.9 3.5e-09 36.9 5.9 3.3 3 2 0 3 3 3 1 Polysaccharide biosynthesis C-terminal domain MAP17 PF15807.5 KXS14500.1 - 0.11 12.8 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Fe_hyd_lg_C PF02906.14 KXS14501.1 - 1.3e-57 195.3 0.0 3.1e-57 194.1 0.0 1.6 1 1 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain F-box PF00646.33 KXS14504.1 - 0.01 15.7 1.1 0.015 15.1 1.1 1.2 1 0 0 1 1 1 0 F-box domain DUF3678 PF12435.8 KXS14504.1 - 2.2 7.7 5.1 3.9 6.9 5.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3678) Acetyltransf_1 PF00583.25 KXS14505.1 - 7e-14 52.1 0.0 9.9e-14 51.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXS14505.1 - 1.1e-08 35.4 0.0 1.6e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXS14505.1 - 2.8e-08 33.6 0.0 7.2e-08 32.3 0.0 1.6 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_9 PF13527.7 KXS14505.1 - 1.6e-07 31.5 0.1 5.2e-07 29.8 0.1 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KXS14505.1 - 6.9e-06 26.0 0.0 1.3e-05 25.1 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KXS14505.1 - 0.0048 17.0 0.0 0.0092 16.1 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_15 PF17013.5 KXS14505.1 - 0.0086 15.6 0.0 0.0086 15.6 0.0 1.2 1 0 0 1 1 1 1 Putative acetyl-transferase Acetyltransf_13 PF13880.6 KXS14505.1 - 0.071 13.1 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase TauD PF02668.16 KXS14506.1 - 2.2e-53 181.8 0.2 3e-53 181.4 0.2 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.16 KXS14507.1 - 1.1e-16 60.7 28.7 6.2e-16 58.3 28.7 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily Tocopherol_cycl PF14249.6 KXS14510.1 - 5.5e-10 38.9 3.9 6.2e-10 38.7 3.9 1.2 1 0 0 1 1 1 1 Tocopherol cyclase AMPK1_CBM PF16561.5 KXS14511.1 - 7e-07 29.4 0.0 9.4e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase CBM_48 PF02922.18 KXS14511.1 - 1.4e-05 25.3 0.1 1.8e-05 25.0 0.1 1.2 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) CBM53 PF16760.5 KXS14511.1 - 0.0033 18.0 0.5 0.0051 17.4 0.5 1.4 1 1 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) RHS PF03527.14 KXS14511.1 - 0.019 14.7 0.3 0.066 13.0 0.1 1.9 2 0 0 2 2 2 0 RHS protein PLAC8 PF04749.17 KXS14512.1 - 1.6e-20 73.9 4.7 2.8e-20 73.2 4.7 1.4 1 0 0 1 1 1 1 PLAC8 family MARVEL PF01284.23 KXS14516.1 - 1.1e-05 25.5 26.0 2.7e-05 24.2 26.0 1.6 1 1 0 1 1 1 1 Membrane-associating domain DUF2070 PF09843.9 KXS14516.1 - 1.1 7.5 5.9 1.3 7.3 5.9 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) HtrL_YibB PF09612.10 KXS14518.1 - 3.6e-07 30.0 0.0 3.3e-06 26.8 0.0 2.1 1 1 0 1 1 1 1 Bacterial protein of unknown function (HtrL_YibB) MFS_1 PF07690.16 KXS14519.1 - 1.3e-21 77.0 59.9 2.4e-16 59.6 31.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Histone_H2A_C PF16211.5 KXS14520.1 - 4.6e-20 71.1 1.1 1e-19 69.9 1.1 1.6 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KXS14520.1 - 9.6e-17 61.6 0.0 1.2e-16 61.2 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KXS14520.1 - 7e-06 26.2 0.0 1e-05 25.7 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KXS14521.1 - 6.6e-22 78.3 0.6 7.8e-22 78.0 0.6 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KXS14521.1 - 6.1e-05 23.2 0.0 0.00014 22.0 0.0 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KXS14521.1 - 0.0026 18.2 0.0 0.0044 17.5 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A RP-C PF03428.13 KXS14521.1 - 0.087 12.5 0.1 0.21 11.2 0.1 1.6 1 1 0 1 1 1 0 Replication protein C N-terminal domain DUF1018 PF06252.12 KXS14521.1 - 0.1 13.6 0.4 0.16 12.9 0.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1018) NUDIX PF00293.28 KXS14523.1 - 1.3e-09 38.2 0.0 2.2e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain UNC-93 PF05978.16 KXS14525.1 - 0.061 13.0 0.1 0.061 13.0 0.1 2.6 3 0 0 3 3 3 0 Ion channel regulatory protein UNC-93 dCache_1 PF02743.18 KXS14526.1 - 0.0015 18.4 0.1 0.0028 17.5 0.1 1.6 1 1 0 1 1 1 1 Cache domain TarH PF02203.15 KXS14526.1 - 0.048 13.6 0.7 0.11 12.4 0.7 1.6 1 0 0 1 1 1 0 Tar ligand binding domain homologue EPO_TPO PF00758.18 KXS14526.1 - 0.42 10.6 1.9 1.6 8.7 0.1 2.2 2 0 0 2 2 2 0 Erythropoietin/thrombopoietin CUTL PF16557.5 KXS14526.1 - 0.52 10.5 2.3 2 8.7 2.3 2.0 1 0 0 1 1 1 0 CUT1-like DNA-binding domain of SATB ParBc PF02195.18 KXS14527.1 - 4e-05 23.8 0.1 6.8e-05 23.1 0.1 1.4 1 0 0 1 1 1 1 ParB-like nuclease domain AAA_33 PF13671.6 KXS14527.1 - 0.094 12.9 0.0 0.24 11.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain EIF_2_alpha PF07541.12 KXS14527.1 - 0.16 12.0 0.0 0.37 10.9 0.0 1.4 1 1 0 1 1 1 0 Eukaryotic translation initiation factor 2 alpha subunit Peptidase_Prp PF04327.12 KXS14528.1 - 0.12 12.6 0.3 0.32 11.3 0.0 1.8 2 1 0 2 2 2 0 Cysteine protease Prp DUF3287 PF11690.8 KXS14528.1 - 0.14 11.9 0.9 0.25 11.1 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) HSBP1 PF06825.12 KXS14528.1 - 0.32 10.9 3.6 0.52 10.2 3.6 1.4 1 0 0 1 1 1 0 Heat shock factor binding protein 1 Ribosomal_L37e PF01907.19 KXS14531.1 - 5.1e-27 93.8 9.0 8.5e-27 93.1 9.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L37e SelR PF01641.18 KXS14531.1 - 0.011 15.8 0.4 0.013 15.6 0.4 1.1 1 0 0 1 1 1 0 SelR domain DZR PF12773.7 KXS14531.1 - 0.031 14.3 1.2 0.047 13.7 1.2 1.3 1 0 0 1 1 1 0 Double zinc ribbon F-box-like PF12937.7 KXS14533.1 - 0.017 15.0 0.1 0.057 13.3 0.1 1.9 1 0 0 1 1 1 0 F-box-like DUF1754 PF08555.10 KXS14535.1 - 7.2e-11 42.7 13.1 7.2e-11 42.7 13.1 2.0 2 1 0 2 2 2 1 Eukaryotic family of unknown function (DUF1754) Peptidase_S46 PF10459.9 KXS14535.1 - 0.081 11.6 3.1 0.093 11.4 3.1 1.0 1 0 0 1 1 1 0 Peptidase S46 FAD_binding_3 PF01494.19 KXS14536.1 - 7.7e-16 58.3 0.7 4.7e-12 45.8 0.1 3.8 2 1 0 2 2 2 2 FAD binding domain SE PF08491.10 KXS14536.1 - 0.00032 19.9 0.0 0.037 13.1 0.0 2.1 2 0 0 2 2 2 2 Squalene epoxidase DER1 PF04511.15 KXS14537.1 - 0.00016 21.6 1.6 0.0034 17.3 1.6 2.1 1 1 0 1 1 1 1 Der1-like family GATase PF00117.28 KXS14538.1 - 3.5e-12 46.5 0.0 4.8e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KXS14538.1 - 1.8e-05 24.6 0.2 0.00011 22.1 0.2 2.0 1 1 0 1 1 1 1 Peptidase C26 WD40 PF00400.32 KXS14539.1 - 2.3e-06 28.2 2.1 0.016 16.1 0.0 3.4 3 0 0 3 3 3 2 WD domain, G-beta repeat Rhodanese PF00581.20 KXS14540.1 - 1.1e-09 38.8 0.0 3.1e-09 37.3 0.0 1.7 2 0 0 2 2 2 1 Rhodanese-like domain Aldolase_II PF00596.21 KXS14541.1 - 5.1e-41 140.7 0.0 6.4e-41 140.3 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain NIF PF03031.18 KXS14542.1 - 0.027 14.3 0.0 0.61 9.8 0.0 2.2 1 1 0 1 1 1 0 NLI interacting factor-like phosphatase Hydrolase PF00702.26 KXS14542.1 - 0.03 14.6 0.0 0.082 13.2 0.0 1.6 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KXS14542.1 - 0.041 13.9 0.0 0.073 13.1 0.0 1.4 1 0 0 1 1 1 0 HAD-hyrolase-like HAD_2 PF13419.6 KXS14542.1 - 0.2 11.7 0.0 0.31 11.1 0.0 1.4 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase COQ9 PF08511.11 KXS14543.1 - 8.9e-16 57.4 0.2 3.8e-15 55.4 0.2 2.0 1 1 0 1 1 1 1 COQ9 SWIRM-assoc_2 PF16496.5 KXS14544.1 - 0.16 10.9 3.3 0.18 10.6 3.3 1.2 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal Pex2_Pex12 PF04757.14 KXS14545.1 - 7.7e-46 156.5 1.4 9.5e-46 156.2 1.4 1.0 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.6 KXS14545.1 - 1.2e-05 25.1 3.2 1.7e-05 24.6 3.2 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXS14545.1 - 0.0013 18.5 5.3 0.002 18.0 5.3 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXS14545.1 - 0.0017 18.2 4.7 0.0025 17.6 4.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXS14545.1 - 0.0043 17.4 4.3 0.0063 16.8 4.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KXS14545.1 - 0.018 15.1 5.9 0.032 14.2 5.9 1.4 1 0 0 1 1 1 0 RING-type zinc-finger Prok-RING_4 PF14447.6 KXS14545.1 - 0.022 14.6 2.6 0.032 14.1 2.6 1.2 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KXS14545.1 - 0.12 12.5 8.7 0.2 11.8 8.7 1.3 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 KXS14545.1 - 0.21 11.9 1.6 0.43 10.9 1.6 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger domain ATE_N PF04376.13 KXS14545.1 - 0.25 11.7 4.1 0.47 10.9 0.7 2.4 2 1 0 2 2 2 0 Arginine-tRNA-protein transferase, N terminus Glyoxalase PF00903.25 KXS14547.1 - 9.7e-06 25.8 0.0 0.00016 21.9 0.0 2.4 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily zf-MYND PF01753.18 KXS14548.1 - 1.6e-09 37.7 3.1 1.6e-09 37.7 3.1 2.1 2 0 0 2 2 2 1 MYND finger zf-C6H2 PF15801.5 KXS14548.1 - 0.024 14.9 4.0 0.024 14.9 4.0 2.3 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding Chitin_bind_1 PF00187.19 KXS14549.1 - 5.5e-24 84.4 96.5 4.9e-11 42.9 21.1 5.4 5 1 1 6 6 6 3 Chitin recognition protein Aldedh PF00171.22 KXS14550.1 - 2.4e-87 293.4 0.0 2.9e-87 293.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family adh_short PF00106.25 KXS14551.1 - 3.9e-24 85.2 0.1 1.4e-23 83.4 0.1 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXS14551.1 - 2.5e-12 46.9 0.2 7.4e-12 45.3 0.2 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXS14551.1 - 5.6e-06 26.4 0.0 8.6e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXS14551.1 - 0.00045 19.8 0.0 0.00088 18.8 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXS14551.1 - 0.011 15.2 0.0 0.029 13.8 0.0 1.7 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase BCA_ABC_TP_C PF12399.8 KXS14552.1 - 0.13 12.3 1.6 0.17 11.9 0.2 1.8 2 0 0 2 2 2 0 Branched-chain amino acid ATP-binding cassette transporter ThiF PF00899.21 KXS14554.1 - 1.7e-37 129.1 0.0 2.9e-37 128.3 0.0 1.3 1 0 0 1 1 1 1 ThiF family UDPG_MGDP_dh_N PF03721.14 KXS14554.1 - 0.0013 18.3 0.1 0.0026 17.4 0.1 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Sacchrp_dh_NADP PF03435.18 KXS14554.1 - 0.0021 18.3 0.9 0.013 15.7 0.9 2.1 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Ldh_1_N PF00056.23 KXS14554.1 - 0.011 15.8 0.4 0.022 14.9 0.4 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain TrkA_N PF02254.18 KXS14554.1 - 0.032 14.5 0.1 0.059 13.6 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain AlaDh_PNT_C PF01262.21 KXS14554.1 - 0.033 13.5 0.3 0.075 12.3 0.3 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.16 KXS14554.1 - 0.048 13.3 0.1 0.092 12.4 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.27 KXS14554.1 - 0.061 13.9 2.7 0.49 11.0 0.5 2.9 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KXS14554.1 - 0.1 11.8 0.6 0.15 11.3 0.6 1.2 1 0 0 1 1 1 0 FAD binding domain Shikimate_DH PF01488.20 KXS14554.1 - 0.11 12.5 0.4 0.3 11.2 0.2 1.6 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 KXS14554.1 - 0.2 11.5 0.1 0.35 10.7 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PNRC PF15365.6 KXS14555.1 - 6.5e-05 22.6 6.4 6.5e-05 22.6 6.4 6.8 9 0 0 9 9 9 1 Proline-rich nuclear receptor coactivator motif DUF5543 PF17697.1 KXS14556.1 - 1.8 8.9 5.0 2 8.7 0.0 2.7 3 0 0 3 3 3 0 Family of unknown function (DUF5543) PAXIP1_C PF15364.6 KXS14556.1 - 3.5 7.9 8.4 6.2 7.1 4.8 2.4 1 1 1 2 2 2 0 PAXIP1-associated-protein-1 C term PTIP binding protein RRM_1 PF00076.22 KXS14559.1 - 6.2e-23 80.4 0.2 1.4e-05 24.8 0.0 6.6 6 0 0 6 6 6 6 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DLH PF01738.18 KXS14561.1 - 1.7e-19 70.2 0.0 2.3e-19 69.8 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 KXS14561.1 - 0.011 15.4 0.0 0.019 14.6 0.0 1.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold BAAT_C PF08840.11 KXS14561.1 - 0.033 14.1 0.0 0.071 13.0 0.0 1.6 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal STI1 PF17830.1 KXS14561.1 - 0.11 12.4 0.1 0.37 10.8 0.0 1.8 2 0 0 2 2 2 0 STI1 domain AA_permease_2 PF13520.6 KXS14563.1 - 7.2e-43 147.0 62.6 8.7e-43 146.7 62.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXS14563.1 - 3.5e-14 52.3 57.2 5.2e-14 51.7 57.2 1.2 1 0 0 1 1 1 1 Amino acid permease Abhydrolase_3 PF07859.13 KXS14564.1 - 4.5e-35 121.4 0.0 6e-35 121.0 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KXS14564.1 - 4e-15 55.5 0.0 6e-15 55.0 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 KXS14564.1 - 6.3e-05 22.5 0.0 0.0025 17.3 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KXS14564.1 - 0.041 13.2 0.0 0.59 9.4 0.0 2.4 2 1 0 2 2 2 0 Serine aminopeptidase, S33 BAAT_C PF08840.11 KXS14564.1 - 0.049 13.5 0.3 0.11 12.5 0.0 1.6 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Glyco_hydro_16 PF00722.21 KXS14565.1 - 2.2e-24 85.9 0.8 3e-24 85.5 0.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Bestrophin PF01062.21 KXS14566.1 - 3.6e-41 141.5 0.1 5.5e-41 140.9 0.1 1.2 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Bestrophin PF01062.21 KXS14567.1 - 1e-36 126.9 2.7 1.1e-35 123.5 2.7 1.9 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel DUF456 PF04306.13 KXS14567.1 - 0.12 12.6 6.4 1.5 9.1 1.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF456) DUF2244 PF10003.9 KXS14567.1 - 0.49 10.1 5.7 0.67 9.6 0.5 2.3 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) DUF4191 PF13829.6 KXS14567.1 - 2.8 7.2 5.3 4.2 6.6 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) Bestrophin PF01062.21 KXS14568.1 - 6.2e-43 147.3 0.5 8.5e-43 146.8 0.5 1.0 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Peptidase_Mx PF15887.5 KXS14568.1 - 0.02 14.3 0.0 0.029 13.8 0.0 1.2 1 0 0 1 1 1 0 Putative zinc-binding metallo-peptidase Osw5 PF17062.5 KXS14568.1 - 0.035 14.2 1.5 0.13 12.4 1.5 2.0 1 0 0 1 1 1 0 Outer spore wall 5 DUF4191 PF13829.6 KXS14568.1 - 0.14 11.5 2.6 0.89 8.9 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) GRAM PF02893.20 KXS14569.1 - 2.6e-20 72.4 0.1 4e-20 71.8 0.1 1.2 1 0 0 1 1 1 1 GRAM domain rhaM PF05336.13 KXS14571.1 - 6.8e-23 80.8 0.1 8.3e-23 80.5 0.1 1.1 1 0 0 1 1 1 1 L-rhamnose mutarotase Amnionless PF14828.6 KXS14572.1 - 0.026 13.4 0.0 0.047 12.5 0.0 1.3 1 0 0 1 1 1 0 Amnionless CKS PF01111.19 KXS14573.1 - 2.8e-30 104.4 0.6 5.6e-30 103.4 0.6 1.5 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit R3H PF01424.22 KXS14574.1 - 3.6e-06 26.9 0.1 2.9e-05 23.9 0.1 2.5 1 1 0 1 1 1 1 R3H domain F-box-like PF12937.7 KXS14574.1 - 0.00015 21.6 0.1 0.00078 19.3 0.0 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KXS14574.1 - 0.11 12.4 0.5 0.23 11.4 0.0 1.8 2 0 0 2 2 2 0 F-box domain DASH_Spc19 PF08287.11 KXS14574.1 - 0.34 10.8 3.5 0.87 9.5 3.5 1.7 1 0 0 1 1 1 0 Spc19 Snf7 PF03357.21 KXS14575.1 - 1e-11 44.8 27.7 1e-11 44.8 27.7 1.9 1 1 2 3 3 3 1 Snf7 Ist1 PF03398.14 KXS14575.1 - 0.063 13.2 14.1 1.9 8.4 14.1 2.3 1 1 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway ABC_tran_CTD PF16326.5 KXS14575.1 - 0.19 12.0 15.0 0.1 12.8 2.3 2.8 2 1 0 2 2 2 0 ABC transporter C-terminal domain YlqD PF11068.8 KXS14575.1 - 0.24 11.8 25.5 0.23 11.8 6.9 2.3 1 1 1 2 2 2 0 YlqD protein DUF3886 PF13025.6 KXS14575.1 - 0.43 10.8 8.7 1 9.6 7.9 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3886) DUF4037 PF13228.6 KXS14575.1 - 0.69 10.7 4.9 0.82 10.5 2.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4037) CDPS PF16715.5 KXS14575.1 - 0.8 9.3 6.7 0.99 9.0 6.3 1.3 1 1 0 1 1 1 0 Cyclodipeptide synthase DUF3984 PF13136.6 KXS14575.1 - 1.8 7.9 7.3 2.3 7.5 7.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) RNA_pol_Rpb1_5 PF04998.17 KXS14575.1 - 4.8 6.5 9.3 6.3 6.1 9.2 1.3 1 1 0 1 1 1 0 RNA polymerase Rpb1, domain 5 Peptidase_A3 PF02160.15 KXS14575.1 - 6.9 6.1 9.4 11 5.4 2.4 2.1 1 1 1 2 2 2 0 Cauliflower mosaic virus peptidase (A3) NUDIX PF00293.28 KXS14576.1 - 6.4e-07 29.5 0.0 1e-05 25.6 0.0 2.4 1 1 0 1 1 1 1 NUDIX domain DUF104 PF01954.16 KXS14576.1 - 0.074 13.5 0.8 0.18 12.3 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF104 NADH_B2 PF14813.6 KXS14577.1 - 0.00046 19.9 1.6 0.00062 19.5 1.6 1.4 1 0 0 1 1 1 1 NADH dehydrogenase 1 beta subcomplex subunit 2 DUF4381 PF14316.6 KXS14577.1 - 0.0064 16.7 0.5 0.0069 16.6 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4381) Homeodomain PF00046.29 KXS14578.1 - 5.4e-13 48.6 2.4 9.2e-13 47.8 2.4 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KXS14578.1 - 0.34 10.9 5.0 0.11 12.5 0.8 2.2 2 0 0 2 2 2 0 Homeobox KN domain WLM PF08325.10 KXS14579.1 - 4e-53 180.3 0.0 5.9e-53 179.8 0.0 1.2 1 0 0 1 1 1 1 WLM domain zf-RanBP PF00641.18 KXS14579.1 - 1.2e-11 43.7 11.4 1.1e-05 24.6 2.7 2.3 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others DZR PF12773.7 KXS14579.1 - 0.0017 18.3 4.0 0.0048 16.9 4.1 1.7 1 1 0 1 1 1 1 Double zinc ribbon SVIP PF15811.5 KXS14579.1 - 0.029 14.8 5.7 0.062 13.8 0.4 2.4 2 0 0 2 2 2 0 Small VCP/p97-interacting protein zinc_ribbon_15 PF17032.5 KXS14579.1 - 0.045 14.5 1.7 0.072 13.9 1.7 1.3 1 0 0 1 1 1 0 zinc-ribbon family zf-MIZ PF02891.20 KXS14579.1 - 0.082 12.7 1.4 0.5 10.2 0.5 2.2 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger zf-Sec23_Sec24 PF04810.15 KXS14579.1 - 0.099 12.7 1.4 0.37 10.9 0.2 2.3 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger DUF45 PF01863.17 KXS14579.1 - 0.18 11.8 0.2 0.39 10.7 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF45 Rubredoxin PF00301.20 KXS14579.1 - 0.44 10.6 5.7 0.99 9.5 0.4 3.2 3 0 0 3 3 3 0 Rubredoxin Vps36-NZF-N PF16988.5 KXS14579.1 - 1.7 8.1 13.4 0.19 11.1 5.4 2.9 2 1 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain PHD PF00628.29 KXS14579.1 - 6.4 6.8 11.1 3 7.8 4.9 3.1 1 1 2 3 3 3 0 PHD-finger PHD_2 PF13831.6 KXS14579.1 - 9.7 5.8 7.7 9.6 5.9 0.2 3.5 4 0 0 4 4 4 0 PHD-finger Cupin_7 PF12973.7 KXS14580.1 - 5.1e-35 119.3 0.0 8.6e-35 118.5 0.0 1.4 1 0 0 1 1 1 1 ChrR Cupin-like domain Cupin_2 PF07883.11 KXS14580.1 - 0.00029 20.5 1.0 0.0017 18.0 0.2 2.5 3 0 0 3 3 3 1 Cupin domain KduI PF04962.12 KXS14580.1 - 0.067 12.5 0.2 0.53 9.6 0.1 1.9 2 0 0 2 2 2 0 KduI/IolB family GFA PF04828.14 KXS14581.1 - 2.7e-22 78.9 2.7 5.5e-10 39.5 0.0 3.0 3 1 0 3 3 3 2 Glutathione-dependent formaldehyde-activating enzyme Nudix_N_2 PF14803.6 KXS14581.1 - 0.089 12.7 0.0 0.089 12.7 0.0 4.1 5 0 0 5 5 5 0 Nudix N-terminal NOB1_Zn_bind PF08772.11 KXS14581.1 - 0.8 9.9 0.1 0.8 9.9 0.1 3.2 4 0 0 4 4 4 0 Nin one binding (NOB1) Zn-ribbon like zinc_ribbon_2 PF13240.6 KXS14581.1 - 1.8 8.4 6.6 7 6.5 0.0 3.4 3 0 0 3 3 3 0 zinc-ribbon domain DZR PF12773.7 KXS14581.1 - 3.3 7.8 10.6 23 5.1 0.0 3.8 3 1 0 3 3 3 0 Double zinc ribbon CC2D2AN-C2 PF15625.6 KXS14582.1 - 7.9e-11 42.0 0.0 7.2e-06 25.8 0.1 2.4 2 0 0 2 2 2 2 CC2D2A N-terminal C2 domain C2 PF00168.30 KXS14582.1 - 0.00014 22.1 0.0 0.00038 20.7 0.0 1.8 1 0 0 1 1 1 1 C2 domain DUF1525 PF07511.11 KXS14582.1 - 0.26 11.5 0.7 0.63 10.2 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1525) Peptidase_M41 PF01434.18 KXS14583.1 - 0.049 13.5 0.1 2.6 7.8 0.0 2.2 1 1 1 2 2 2 0 Peptidase family M41 FMN_red PF03358.15 KXS14584.1 - 2e-21 76.4 0.0 2.6e-21 76.0 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase TTC5_OB PF16669.5 KXS14586.1 - 1.2e-06 28.2 0.0 2e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat protein 5 OB fold domain TPR_2 PF07719.17 KXS14586.1 - 0.11 12.7 1.3 7.9 6.9 0.1 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat SOG2 PF10428.9 KXS14586.1 - 1.4 8.1 28.6 0.44 9.7 16.1 2.2 2 0 0 2 2 2 0 RAM signalling pathway protein ATF7IP_BD PF16788.5 KXS14586.1 - 9 6.3 15.6 0.18 11.9 5.4 2.2 2 0 0 2 2 2 0 ATF-interacting protein binding domain Thioredoxin PF00085.20 KXS14587.1 - 9.2e-24 83.4 0.0 1.3e-23 82.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin UBX PF00789.20 KXS14587.1 - 2.5e-07 30.8 0.0 4.4e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 UBX domain Thioredoxin_7 PF13899.6 KXS14587.1 - 6.5e-05 23.0 0.0 0.00012 22.2 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 KXS14587.1 - 0.0013 19.1 0.1 0.016 15.7 0.1 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.21 KXS14587.1 - 0.0038 17.1 0.0 0.0068 16.3 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_9 PF14595.6 KXS14587.1 - 0.005 16.6 0.0 0.0071 16.1 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Nucleocap_ssRNA PF11128.8 KXS14587.1 - 0.066 12.9 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Plant viral coat protein nucleocapsid Redoxin PF08534.10 KXS14587.1 - 0.096 12.4 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 Redoxin Thioredoxin_8 PF13905.6 KXS14587.1 - 0.1 13.0 0.0 0.16 12.3 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like Phosducin PF02114.16 KXS14587.1 - 0.11 11.4 0.0 0.16 10.9 0.0 1.1 1 0 0 1 1 1 0 Phosducin Patatin PF01734.22 KXS14591.1 - 6.2e-17 62.4 2.9 6.2e-17 62.4 2.9 3.7 3 1 0 3 3 3 1 Patatin-like phospholipase cNMP_binding PF00027.29 KXS14591.1 - 6.7e-12 45.3 0.0 0.03 14.4 0.0 4.9 5 0 0 5 5 5 3 Cyclic nucleotide-binding domain SH3_9 PF14604.6 KXS14592.1 - 0.00023 20.9 0.0 0.00048 19.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXS14592.1 - 0.011 15.4 0.0 0.087 12.4 0.0 2.2 2 0 0 2 2 2 0 SH3 domain zf-C2H2 PF00096.26 KXS14593.1 - 5.9e-10 39.1 5.9 2.7e-05 24.4 1.0 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KXS14593.1 - 7.9e-09 35.5 4.1 1.4e-08 34.8 0.6 2.5 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KXS14593.1 - 2.3e-08 34.2 3.9 0.00031 21.3 0.5 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KXS14593.1 - 0.00022 21.1 2.3 0.095 12.7 0.1 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KXS14593.1 - 0.00083 19.1 2.7 0.0031 17.2 0.4 2.3 2 0 0 2 2 2 1 zinc-finger C2H2-type zf-met PF12874.7 KXS14593.1 - 0.0013 19.1 1.1 0.68 10.4 0.2 2.4 2 0 0 2 2 2 2 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.10 KXS14593.1 - 0.19 11.9 2.0 0.71 10.0 2.0 1.9 1 1 1 2 2 2 0 Zinc ribbon domain zf_UBZ PF18439.1 KXS14593.1 - 0.38 10.4 1.0 7.2 6.3 0.1 2.4 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-H2C2_5 PF13909.6 KXS14593.1 - 9.1 6.1 8.5 1.4 8.8 3.8 2.2 2 1 0 2 2 2 0 C2H2-type zinc-finger domain PPP1R35_C PF15503.6 KXS14595.1 - 0.12 12.2 0.6 1.3 8.8 0.0 2.4 2 0 0 2 2 2 0 Protein phosphatase 1 regulatory subunit 35 C-terminus Peripla_BP_2 PF01497.18 KXS14596.1 - 6.8e-08 32.4 0.0 3.5e-07 30.0 0.0 1.9 1 1 1 2 2 2 1 Periplasmic binding protein Spt4 PF06093.13 KXS14597.1 - 3.7e-30 103.9 0.3 4.4e-30 103.6 0.3 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger WW PF00397.26 KXS14598.1 - 9.9e-11 41.5 2.2 2.6e-10 40.2 2.2 1.8 1 0 0 1 1 1 1 WW domain Sel_put PF04328.13 KXS14598.1 - 0.08 13.0 0.9 0.17 11.9 0.9 1.5 1 0 0 1 1 1 0 Selenoprotein, putative Med19 PF10278.9 KXS14598.1 - 6 6.8 11.5 9.1 6.2 3.0 2.3 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 Peptidase_M24 PF00557.24 KXS14599.1 - 2.1e-57 194.2 0.0 2.9e-57 193.8 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 KXS14599.1 - 1.4e-20 73.2 0.1 1.2e-19 70.3 0.0 2.2 2 0 0 2 2 2 1 Aminopeptidase P, N-terminal domain ATP-grasp_2 PF08442.10 KXS14601.1 - 4.9e-75 251.5 0.3 8.3e-75 250.8 0.3 1.4 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 KXS14601.1 - 7.6e-27 94.0 0.9 1.3e-26 93.2 0.9 1.4 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 KXS14601.1 - 2.7e-07 30.3 0.3 7.5e-07 28.8 0.3 1.7 1 1 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 KXS14601.1 - 0.0017 18.2 0.0 0.0059 16.4 0.0 1.9 1 1 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain OKR_DC_1_N PF03709.15 KXS14601.1 - 0.035 14.4 0.0 0.094 13.0 0.0 1.7 1 1 0 1 1 1 0 Orn/Lys/Arg decarboxylase, N-terminal domain zf-C2H2 PF00096.26 KXS14602.1 - 2.1e-06 27.9 22.4 2.1e-05 24.7 1.2 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KXS14602.1 - 3.7e-06 27.1 8.7 0.00011 22.5 1.8 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KXS14602.1 - 0.0035 17.6 4.0 0.4 11.0 2.7 2.3 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 KXS14602.1 - 0.0055 17.4 19.0 0.0069 17.1 0.4 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KXS14602.1 - 0.0065 16.4 11.9 0.091 12.8 0.0 2.3 2 0 0 2 2 2 1 C2H2-type zinc finger ADK_lid PF05191.14 KXS14602.1 - 0.0081 16.1 1.7 0.022 14.8 1.7 1.8 1 0 0 1 1 1 1 Adenylate kinase, active site lid DUF2256 PF10013.9 KXS14602.1 - 0.058 13.5 0.4 7 6.9 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) zf_C2H2_ZHX PF18387.1 KXS14602.1 - 0.39 10.4 6.4 1.4 8.6 0.0 2.4 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain COG6 PF06419.11 KXS14603.1 - 0.057 11.6 0.7 0.1 10.8 0.5 1.4 2 0 0 2 2 2 0 Conserved oligomeric complex COG6 SlyX PF04102.12 KXS14603.1 - 0.066 13.8 4.2 0.23 12.1 1.4 2.6 2 0 0 2 2 2 0 SlyX FAD-oxidase_C PF02913.19 KXS14604.1 - 3.2e-54 184.2 0.2 6.3e-54 183.2 0.0 1.5 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KXS14604.1 - 1.2e-35 122.3 0.2 2.3e-35 121.4 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain DUF747 PF05346.11 KXS14605.1 - 5.3e-94 315.3 0.0 7.2e-94 314.8 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family CutA1 PF03091.15 KXS14608.1 - 8.5e-36 121.8 0.1 9.9e-36 121.6 0.1 1.0 1 0 0 1 1 1 1 CutA1 divalent ion tolerance protein Ctf8 PF09696.10 KXS14609.1 - 2.7e-09 37.5 0.0 2e-06 28.2 0.0 2.8 1 1 1 2 2 2 2 Ctf8 zf-H2C2_2 PF13465.6 KXS14610.1 - 2.9e-10 40.1 5.5 3.6e-08 33.5 0.4 2.7 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 KXS14610.1 - 2.1e-08 34.2 10.0 5.2e-05 23.5 1.2 2.5 3 0 0 3 3 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXS14610.1 - 2.5e-08 34.0 4.0 0.0011 19.7 0.8 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KXS14610.1 - 7.9e-05 22.6 0.9 0.021 14.8 0.0 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger C5HCH PF17982.1 KXS14610.1 - 0.013 15.7 1.2 0.42 10.8 0.1 2.4 2 0 0 2 2 2 0 NSD Cys-His rich domain Zn-ribbon_8 PF09723.10 KXS14610.1 - 0.015 15.4 2.3 0.18 12.0 0.2 2.2 2 0 0 2 2 2 0 Zinc ribbon domain C1_4 PF07975.12 KXS14610.1 - 0.025 14.8 2.6 0.33 11.2 0.1 2.2 1 1 1 2 2 2 0 TFIIH C1-like domain zf-C2H2_jaz PF12171.8 KXS14610.1 - 0.052 13.9 1.1 4.1 7.8 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding RNA_POL_M_15KD PF02150.16 KXS14610.1 - 0.057 13.3 0.7 0.28 11.1 0.0 2.1 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit zf-C2H2_3rep PF18868.1 KXS14610.1 - 0.088 13.5 2.3 0.84 10.3 0.3 2.0 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-MYST PF17772.1 KXS14610.1 - 0.26 10.9 1.7 1.2 8.8 0.4 2.0 2 0 0 2 2 2 0 MYST family zinc finger domain DUF629 PF04780.12 KXS14610.1 - 0.4 9.2 1.6 2.1 6.8 0.5 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF629) zf-AN1 PF01428.16 KXS14610.1 - 7.6 6.8 10.2 5.8 7.2 0.8 2.5 2 1 1 3 3 3 0 AN1-like Zinc finger NYN PF01936.18 KXS14611.1 - 0.0014 19.2 0.0 0.0023 18.4 0.0 1.3 1 0 0 1 1 1 1 NYN domain Tubulin PF00091.25 KXS14612.1 - 4.4e-67 226.1 0.1 1.3e-66 224.6 0.1 1.8 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KXS14612.1 - 2.4e-33 115.0 0.1 3.8e-33 114.3 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 KXS14612.1 - 5.8e-06 26.6 0.0 1.3e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 KXS14612.1 - 0.19 11.4 0.0 0.35 10.5 0.0 1.4 1 0 0 1 1 1 0 Tubulin domain UQ_con PF00179.26 KXS14613.1 - 1.3e-20 73.4 0.0 2.3e-20 72.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme zf-RanBP PF00641.18 KXS14613.1 - 0.0076 15.6 0.3 0.014 14.7 0.3 1.3 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others SOG2 PF10428.9 KXS14613.1 - 0.056 12.6 15.2 0.08 12.1 15.2 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Tropomyosin_1 PF12718.7 KXS14614.1 - 6.9e-05 23.0 22.3 0.0028 17.8 7.0 2.2 1 1 1 2 2 2 2 Tropomyosin like Spc7 PF08317.11 KXS14614.1 - 0.032 13.1 11.8 0.049 12.5 11.8 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein BRE1 PF08647.11 KXS14614.1 - 1.2 9.2 10.1 0.12 12.5 3.0 2.2 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase GAS PF13851.6 KXS14614.1 - 2.3 7.5 12.2 6.4 6.1 10.6 1.9 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding FUSC PF04632.12 KXS14614.1 - 2.4 6.6 18.0 3.4 6.1 18.0 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family SET PF00856.28 KXS14615.1 - 5.3e-07 30.2 0.0 2.8e-06 27.8 0.0 2.3 2 1 0 2 2 2 1 SET domain Rubis-subs-bind PF09273.11 KXS14615.1 - 0.0021 18.8 0.0 0.0049 17.6 0.0 1.6 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding VID27_N PF17748.1 KXS14615.1 - 0.71 9.7 3.3 0.65 9.8 0.3 2.1 2 0 0 2 2 2 0 VID27 N-terminal region AA_permease_2 PF13520.6 KXS14618.1 - 1.4e-38 132.8 39.1 1.8e-38 132.5 39.1 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXS14618.1 - 1.5e-17 63.4 38.5 2e-17 63.0 38.5 1.1 1 0 0 1 1 1 1 Amino acid permease MSP1_C PF07462.11 KXS14619.1 - 0.1 11.3 0.4 0.14 10.8 0.4 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Thg1 PF04446.12 KXS14620.1 - 1.7e-43 147.6 0.0 2.7e-43 147.0 0.0 1.3 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Thg1C PF14413.6 KXS14620.1 - 2.4e-25 89.1 0.0 1.8e-11 44.3 0.0 2.4 2 0 0 2 2 2 2 Thg1 C terminal domain SET PF00856.28 KXS14621.1 - 7.3e-11 42.7 0.0 1.7e-10 41.6 0.0 1.6 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.18 KXS14621.1 - 0.00016 21.7 6.8 0.00016 21.7 6.8 3.1 3 0 0 3 3 3 1 MYND finger CinA PF02464.17 KXS14622.1 - 5.2e-35 120.3 0.1 5.8e-35 120.1 0.1 1.0 1 0 0 1 1 1 1 Competence-damaged protein LRR_8 PF13855.6 KXS14623.1 - 1.1e-05 25.1 0.7 0.00039 20.1 0.6 2.4 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KXS14623.1 - 2.8e-05 24.4 0.7 0.0056 17.1 0.1 2.8 1 1 3 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KXS14623.1 - 0.056 14.0 0.3 20 6.2 0.1 3.7 3 1 0 3 3 3 0 Leucine Rich Repeat Latarcin PF10279.9 KXS14624.1 - 0.027 14.9 0.2 0.071 13.5 0.1 1.7 2 0 0 2 2 2 0 Latarcin precursor T2SSF PF00482.23 KXS14624.1 - 0.035 14.1 0.2 0.1 12.5 0.0 1.9 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F DUF1216 PF06746.11 KXS14624.1 - 0.11 12.6 0.1 0.25 11.3 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1216) Beta-lactamase PF00144.24 KXS14625.1 - 1.6e-40 139.4 5.4 3.7e-40 138.2 5.4 1.6 1 1 0 1 1 1 1 Beta-lactamase FUSC PF04632.12 KXS14626.1 - 0.38 9.2 2.6 0.58 8.6 2.6 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family LAG1-DNAbind PF09271.11 KXS14627.1 - 7.5e-19 68.8 0.1 2.8e-18 67.0 0.0 2.1 2 0 0 2 2 2 1 LAG1, DNA binding BTD PF09270.10 KXS14627.1 - 1.1e-10 42.0 0.0 4.7e-06 26.9 0.0 2.4 2 0 0 2 2 2 2 Beta-trefoil DNA-binding domain TIG PF01833.24 KXS14627.1 - 0.0026 17.8 0.0 0.0081 16.2 0.0 1.8 1 0 0 1 1 1 1 IPT/TIG domain TFIIF_alpha PF05793.12 KXS14627.1 - 9.7 4.7 22.5 20 3.6 22.5 1.5 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PhoD PF09423.10 KXS14628.1 - 0.026 13.6 0.0 1 8.3 0.0 2.2 2 0 0 2 2 2 0 PhoD-like phosphatase Abhydrolase_1 PF00561.20 KXS14629.1 - 4.2e-45 154.4 0.0 8.6e-45 153.4 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 KXS14629.1 - 0.00025 20.8 0.0 0.00041 20.1 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 KXS14629.1 - 0.0017 17.6 0.0 0.086 12.1 0.1 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KXS14629.1 - 0.027 15.1 3.0 0.084 13.5 3.0 1.9 1 1 0 1 1 1 0 Alpha/beta hydrolase family TP_methylase PF00590.20 KXS14630.1 - 2e-34 119.4 0.3 1e-33 117.1 0.3 1.9 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Sacchrp_dh_NADP PF03435.18 KXS14631.1 - 3.9e-14 53.0 0.2 6.7e-14 52.3 0.2 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NMO PF03060.15 KXS14632.1 - 9.3e-59 199.5 0.5 6.3e-58 196.7 0.5 1.8 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KXS14632.1 - 4.9e-13 48.8 1.3 1.7e-10 40.4 1.2 2.3 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NanE PF04131.14 KXS14632.1 - 0.00025 20.3 0.1 0.00025 20.3 0.1 1.8 2 0 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase FMN_dh PF01070.18 KXS14632.1 - 0.018 14.1 2.0 0.052 12.6 1.8 1.7 1 1 0 1 1 1 0 FMN-dependent dehydrogenase TMP-TENI PF02581.17 KXS14632.1 - 0.076 12.3 0.1 0.15 11.4 0.1 1.4 1 0 0 1 1 1 0 Thiamine monophosphate synthase NicO PF03824.16 KXS14633.1 - 0.048 13.0 1.0 4.9 6.4 0.1 2.1 1 1 1 2 2 2 0 High-affinity nickel-transport protein TMCCDC2 PF15844.5 KXS14633.1 - 0.14 12.1 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Transmembrane and coiled-coil domain-containing protein 2 Transport_MerF PF11431.8 KXS14633.1 - 0.44 10.5 3.5 1.4 8.9 0.6 2.5 2 0 0 2 2 2 0 Membrane transport protein MerF VTC PF09359.10 KXS14634.1 - 2.3e-95 319.1 0.0 3.3e-95 318.6 0.0 1.2 1 0 0 1 1 1 1 VTC domain SPX PF03105.19 KXS14634.1 - 1e-17 65.1 16.7 3.1e-07 30.7 0.4 3.7 2 1 2 4 4 4 3 SPX domain DUF202 PF02656.15 KXS14634.1 - 4.3e-14 52.7 4.8 4.3e-14 52.7 4.8 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) zf-CDGSH PF09360.10 KXS14635.1 - 3.7e-15 55.9 2.5 1.3e-07 31.7 0.4 2.5 2 0 0 2 2 2 2 Iron-binding zinc finger CDGSH type Acyl-CoA_dh_1 PF00441.24 KXS14636.1 - 3.9e-46 157.0 0.3 6.3e-46 156.3 0.3 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KXS14636.1 - 3.6e-26 92.0 0.0 1.5e-25 90.0 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KXS14636.1 - 9.9e-26 89.8 0.1 2.4e-25 88.5 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KXS14636.1 - 1.1e-20 74.2 0.0 1.9e-20 73.5 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 KXS14636.1 - 0.018 14.7 0.1 0.042 13.5 0.1 1.6 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal AgrD PF05931.11 KXS14636.1 - 0.022 14.8 0.0 0.054 13.5 0.0 1.6 1 0 0 1 1 1 0 Staphylococcal AgrD protein URO-D PF01208.17 KXS14637.1 - 1.7e-125 418.8 0.0 1.9e-125 418.6 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) GTP_EFTU PF00009.27 KXS14638.1 - 1.2e-32 113.0 0.0 8.9e-32 110.2 0.0 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 KXS14638.1 - 8.3e-19 67.7 0.0 2.5e-18 66.1 0.0 1.9 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D4 PF14578.6 KXS14638.1 - 8.9e-12 44.8 0.5 2.8e-11 43.1 0.5 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 4 GTP_EFTU_D2 PF03144.25 KXS14638.1 - 3.8e-10 40.0 8.3 2e-08 34.5 0.1 3.4 3 0 0 3 3 3 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KXS14638.1 - 6.7e-07 29.4 0.1 1.3e-05 25.2 0.0 2.8 3 0 0 3 3 3 1 50S ribosome-binding GTPase eIF3_subunit PF08597.10 KXS14638.1 - 0.00032 20.7 33.7 0.00032 20.7 33.7 5.8 1 1 4 5 5 5 1 Translation initiation factor eIF3 subunit ATP_bind_1 PF03029.17 KXS14638.1 - 0.0041 16.9 0.0 0.024 14.4 0.0 2.3 2 1 0 2 2 2 1 Conserved hypothetical ATP binding protein Roc PF08477.13 KXS14638.1 - 0.0042 17.3 0.0 0.011 16.0 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA PF00004.29 KXS14639.1 - 7.8e-61 204.3 0.0 1.3e-45 155.1 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KXS14639.1 - 1.3e-12 48.4 1.6 0.00018 22.0 0.1 3.8 2 1 0 3 3 3 2 AAA ATPase domain AAA_lid_3 PF17862.1 KXS14639.1 - 1.1e-08 34.7 0.4 0.0003 20.5 0.0 2.8 2 0 0 2 2 2 2 AAA+ lid domain AAA_5 PF07728.14 KXS14639.1 - 5.2e-06 26.5 0.2 0.0097 15.9 0.1 3.7 4 1 0 4 4 3 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KXS14639.1 - 6e-06 26.5 0.0 0.13 12.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.6 KXS14639.1 - 1.5e-05 25.1 0.0 0.25 11.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.12 KXS14639.1 - 3.7e-05 23.5 0.0 0.0011 18.8 0.0 2.6 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KXS14639.1 - 6.3e-05 23.3 0.1 0.0066 16.7 0.1 3.2 2 1 1 3 3 3 1 AAA domain RNA_helicase PF00910.22 KXS14639.1 - 0.00037 20.9 0.0 0.018 15.4 0.0 2.5 2 0 0 2 2 2 1 RNA helicase AAA_2 PF07724.14 KXS14639.1 - 0.0004 20.5 0.0 0.004 17.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_7 PF12775.7 KXS14639.1 - 0.0013 18.3 0.0 0.013 15.1 0.0 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region Sigma54_activat PF00158.26 KXS14639.1 - 0.0013 18.5 0.1 0.55 9.9 0.0 2.7 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_18 PF13238.6 KXS14639.1 - 0.0014 19.2 4.0 0.014 16.0 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_3 PF07726.11 KXS14639.1 - 0.0026 17.6 0.0 0.12 12.2 0.0 2.8 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 KXS14639.1 - 0.0028 17.3 1.7 0.068 12.7 0.1 3.2 2 2 0 2 2 2 1 AAA domain Rad17 PF03215.15 KXS14639.1 - 0.0031 17.5 0.0 1.1 9.2 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain TsaE PF02367.17 KXS14639.1 - 0.0032 17.5 0.1 0.092 12.8 0.0 2.3 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 KXS14639.1 - 0.0033 16.9 0.3 0.0091 15.4 0.1 1.8 2 0 0 2 2 1 1 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 KXS14639.1 - 0.0037 16.5 0.0 0.0091 15.2 0.0 1.6 1 0 0 1 1 1 1 TIP49 P-loop domain IstB_IS21 PF01695.17 KXS14639.1 - 0.006 16.3 0.1 0.031 14.0 0.0 2.0 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_17 PF13207.6 KXS14639.1 - 0.0076 16.7 0.2 2.4 8.6 0.0 3.2 3 0 0 3 3 3 1 AAA domain ATPase PF06745.13 KXS14639.1 - 0.0077 15.6 0.0 0.02 14.2 0.0 1.6 1 0 0 1 1 1 1 KaiC Parvo_NS1 PF01057.17 KXS14639.1 - 0.012 14.8 0.0 0.024 13.8 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_28 PF13521.6 KXS14639.1 - 0.012 15.8 0.1 0.63 10.3 0.0 3.2 2 1 1 3 3 3 0 AAA domain NTPase_1 PF03266.15 KXS14639.1 - 0.014 15.3 0.1 2.7 7.9 0.0 2.6 2 0 0 2 2 2 0 NTPase DUF815 PF05673.13 KXS14639.1 - 0.015 14.5 0.0 0.32 10.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_24 PF13479.6 KXS14639.1 - 0.023 14.4 2.2 0.065 12.9 0.1 2.5 3 0 0 3 3 2 0 AAA domain NACHT PF05729.12 KXS14639.1 - 0.024 14.6 0.1 4.8 7.1 0.0 3.0 3 0 0 3 3 2 0 NACHT domain CbiA PF01656.23 KXS14639.1 - 0.028 14.5 0.0 1.1 9.4 0.0 2.4 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_11 PF13086.6 KXS14639.1 - 0.031 14.1 0.4 0.52 10.0 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA_6 PF12774.7 KXS14639.1 - 0.055 12.4 0.2 4.9 6.0 0.0 2.2 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region Cytidylate_kin2 PF13189.6 KXS14639.1 - 0.06 13.5 0.3 3.3 7.8 0.0 3.0 3 0 0 3 3 3 0 Cytidylate kinase-like family PhoH PF02562.16 KXS14639.1 - 0.1 12.0 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein ATPase_2 PF01637.18 KXS14639.1 - 0.11 12.3 0.0 14 5.5 0.0 2.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_19 PF13245.6 KXS14639.1 - 0.15 12.3 0.5 1.3 9.3 0.1 2.3 2 0 0 2 2 2 0 AAA domain PPV_E1_C PF00519.17 KXS14639.1 - 0.28 10.0 0.0 1.9 7.2 0.0 2.1 2 0 0 2 2 2 0 Papillomavirus helicase AAA_29 PF13555.6 KXS14639.1 - 0.32 10.8 0.9 10 5.9 0.2 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain Retrotran_gag_2 PF14223.6 KXS14641.1 - 0.011 15.4 0.0 0.69 9.6 0.0 2.5 2 1 1 3 3 3 0 gag-polypeptide of LTR copia-type CMS1 PF14617.6 KXS14643.1 - 5.8e-18 65.2 0.1 5.8e-18 65.2 0.1 1.9 1 1 1 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.29 KXS14643.1 - 0.005 16.6 0.1 0.0071 16.1 0.1 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-CCHC_3 PF13917.6 KXS14644.1 - 5.3e-09 35.9 2.1 9.1e-09 35.1 2.1 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 KXS14644.1 - 0.011 15.8 1.3 0.017 15.2 1.3 1.3 1 0 0 1 1 1 0 Zinc knuckle RNA_polI_A34 PF08208.11 KXS14644.1 - 0.035 14.2 12.0 0.041 14.0 12.0 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 PAPA-1 PF04795.12 KXS14644.1 - 0.058 14.2 3.5 0.092 13.5 3.5 1.4 1 1 0 1 1 1 0 PAPA-1-like conserved region Nop14 PF04147.12 KXS14644.1 - 2.2 6.4 12.5 2.4 6.3 12.5 1.0 1 0 0 1 1 1 0 Nop14-like family DUF4636 PF15468.6 KXS14644.1 - 2.2 7.9 12.6 3.7 7.2 12.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4636) NAM-associated PF14303.6 KXS14644.1 - 6.2 7.5 16.5 8.4 7.1 16.5 1.3 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Ribosom_S12_S23 PF00164.25 KXS14645.1 - 2.4e-52 175.3 0.3 3.1e-52 175.0 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 VWA_2 PF13519.6 KXS14646.1 - 4.8e-25 88.3 0.8 6.3e-24 84.7 0.1 2.6 2 1 1 3 3 3 1 von Willebrand factor type A domain UIM PF02809.20 KXS14646.1 - 3.8e-09 35.8 10.0 0.0015 18.3 0.2 3.8 3 0 0 3 3 3 3 Ubiquitin interaction motif Ssl1 PF04056.14 KXS14646.1 - 3e-06 27.2 0.0 4.7e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like VWA PF00092.28 KXS14646.1 - 0.0004 20.7 0.4 0.00064 20.0 0.4 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF5406 PF17400.2 KXS14646.1 - 0.12 12.8 0.1 29 5.1 0.0 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5406) LRR_6 PF13516.6 KXS14651.1 - 2.2e-72 233.0 56.5 3.7e-07 29.7 0.1 13.6 13 0 0 13 13 13 13 Leucine Rich repeat LRR_4 PF12799.7 KXS14651.1 - 7.6e-24 83.4 27.2 0.0002 21.7 0.6 9.0 3 3 8 11 11 11 10 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXS14651.1 - 6.4e-19 67.5 36.0 2.1e-05 24.2 3.4 10.0 2 2 5 8 8 8 7 Leucine rich repeat LRR_1 PF00560.33 KXS14651.1 - 4.1e-14 51.0 12.7 5.9 7.8 0.0 12.3 11 2 1 12 12 12 2 Leucine Rich Repeat SH3_1 PF00018.28 KXS14652.1 - 1.2e-05 24.8 0.0 2.3e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KXS14652.1 - 0.0008 19.2 0.0 0.0012 18.7 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KXS14652.1 - 0.025 14.3 0.0 0.04 13.6 0.0 1.3 1 0 0 1 1 1 0 Variant SH3 domain Sdh5 PF03937.16 KXS14652.1 - 0.17 11.9 0.0 0.29 11.1 0.0 1.3 1 0 0 1 1 1 0 Flavinator of succinate dehydrogenase Pkinase PF00069.25 KXS14653.1 - 5.1e-44 150.6 0.0 7e-44 150.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS14653.1 - 3.5e-42 144.5 0.0 4.2e-42 144.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXS14653.1 - 0.0003 20.2 0.0 0.0004 19.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KXS14653.1 - 0.0024 17.5 0.0 0.0034 17.0 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 KXS14653.1 - 0.0074 15.7 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 KXS14653.1 - 0.015 14.4 0.0 0.021 13.9 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 KXS14653.1 - 0.023 14.6 0.0 0.046 13.6 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXS14653.1 - 0.11 11.3 0.0 0.16 10.8 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase DUF3510 PF12022.8 KXS14654.1 - 2.4e-32 111.9 2.3 4.2e-32 111.2 0.2 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3510) COG2 PF06148.11 KXS14654.1 - 9.3e-19 67.8 0.3 9.3e-19 67.8 0.3 2.3 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF2203 PF09969.9 KXS14654.1 - 2 9.2 5.0 4.6 8.0 0.7 3.4 5 0 0 5 5 5 0 Uncharacterized conserved protein (DUF2203) SET PF00856.28 KXS14656.1 - 8.1e-08 32.8 0.0 9.5e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 SET domain Bac_rhamnosid6H PF17389.2 KXS14657.1 - 2.6e-06 26.9 0.0 2.3e-05 23.8 0.0 2.1 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain adh_short_C2 PF13561.6 KXS14658.1 - 1.4e-57 194.9 0.1 1.6e-57 194.7 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXS14658.1 - 2.6e-42 144.5 0.5 3.1e-42 144.2 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXS14658.1 - 2.5e-08 34.1 0.4 4.3e-08 33.3 0.4 1.3 1 0 0 1 1 1 1 KR domain 2-Hacid_dh_C PF02826.19 KXS14659.1 - 4.3e-44 150.0 0.0 5.6e-44 149.6 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KXS14659.1 - 4.3e-16 58.8 0.0 5e-16 58.6 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain UDPG_MGDP_dh_N PF03721.14 KXS14659.1 - 0.012 15.2 0.0 0.022 14.3 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_2 PF03446.15 KXS14659.1 - 0.066 13.4 0.0 0.1 12.8 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase MFS_1 PF07690.16 KXS14660.1 - 1.8e-20 73.2 37.6 5.9e-12 45.2 19.7 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily QCR10 PF09796.9 KXS14660.1 - 0.34 11.0 11.8 1.7 8.8 0.0 4.7 2 1 2 4 4 4 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) RraA-like PF03737.15 KXS14661.1 - 1.5e-18 67.4 0.7 2.1e-18 66.9 0.7 1.2 1 0 0 1 1 1 1 Aldolase/RraA SOUL PF04832.12 KXS14664.1 - 1.3e-44 152.3 1.4 5.1e-26 91.8 0.1 3.0 1 1 1 2 2 2 2 SOUL heme-binding protein Ank_2 PF12796.7 KXS14665.1 - 6.5e-07 29.8 0.0 1.2e-06 29.0 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXS14665.1 - 1.7e-05 24.8 0.4 1.6 9.6 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 KXS14665.1 - 1.9e-05 24.9 1.1 2.1 8.9 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 KXS14665.1 - 0.0012 19.4 0.3 0.024 15.2 0.1 2.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXS14665.1 - 0.012 16.0 0.0 1.1 9.7 0.0 2.8 2 1 0 2 2 2 0 Ankyrin repeats (many copies) F-box-like PF12937.7 KXS14666.1 - 0.00082 19.2 0.1 0.0017 18.2 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXS14666.1 - 0.012 15.5 0.2 0.029 14.2 0.2 1.6 1 0 0 1 1 1 0 F-box domain GATA PF00320.27 KXS14667.1 - 1.5e-13 50.1 6.1 2.6e-13 49.3 6.1 1.4 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.10 KXS14667.1 - 8.9e-10 38.2 0.9 1.7e-09 37.4 0.9 1.4 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Fungal_trans PF04082.18 KXS14668.1 - 0.0038 16.3 0.0 0.0065 15.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-RING_2 PF13639.6 KXS14670.1 - 5.3e-13 49.1 5.0 8.1e-13 48.5 5.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KXS14670.1 - 5.5e-09 35.7 4.1 8.4e-09 35.1 4.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KXS14670.1 - 1.7e-08 34.1 0.8 3.4e-08 33.1 0.8 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 KXS14670.1 - 1.2e-07 31.4 1.7 1.8e-07 30.9 1.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXS14670.1 - 2.7e-07 30.5 3.5 9.2e-07 28.8 0.8 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 KXS14670.1 - 8.3e-07 28.9 1.8 1.2e-06 28.3 1.8 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 KXS14670.1 - 1.3e-06 28.5 6.7 5.1e-06 26.7 6.7 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 KXS14670.1 - 1.2e-05 25.1 3.5 1.8e-05 24.5 3.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KXS14670.1 - 3.9e-05 23.6 1.7 6.8e-05 22.8 1.7 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 KXS14670.1 - 0.00058 19.7 4.4 0.017 15.0 5.4 2.1 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KXS14670.1 - 0.0006 19.9 3.0 0.0011 19.1 3.0 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 KXS14670.1 - 0.0016 18.2 2.4 0.0024 17.6 2.4 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Rad50_zn_hook PF04423.14 KXS14670.1 - 0.0055 16.5 1.6 0.24 11.3 0.2 2.3 2 0 0 2 2 2 1 Rad50 zinc hook motif Zn_ribbon_17 PF17120.5 KXS14670.1 - 0.037 13.7 2.8 0.065 12.9 2.8 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 KXS14670.1 - 0.044 14.0 3.0 0.51 10.5 3.1 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain SLAC1 PF03595.17 KXS14670.1 - 0.058 12.7 0.9 0.084 12.1 0.3 1.5 2 0 0 2 2 2 0 Voltage-dependent anion channel TackOD1 PF18551.1 KXS14670.1 - 0.12 12.1 0.2 0.17 11.5 0.2 1.2 1 0 0 1 1 1 0 Thaumarchaeal output domain 1 Vps39_2 PF10367.9 KXS14670.1 - 0.19 12.2 2.7 0.44 11.0 0.3 2.2 1 1 1 2 2 2 0 Vacuolar sorting protein 39 domain 2 zf-RING-like PF08746.11 KXS14670.1 - 0.61 10.4 5.3 0.14 12.5 1.3 1.9 2 0 0 2 2 2 0 RING-like domain zf-C3H2C3 PF17122.5 KXS14670.1 - 7.6 6.7 7.6 1.3 9.1 2.2 2.2 2 1 0 2 2 2 0 Zinc-finger zf-C2H2 PF00096.26 KXS14671.1 - 3e-24 84.1 29.8 1.9e-05 24.8 2.2 5.1 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KXS14671.1 - 4e-23 80.8 28.3 9.3e-07 29.0 0.4 5.5 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 KXS14671.1 - 1.2e-12 47.6 27.6 0.058 14.3 1.5 5.2 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KXS14671.1 - 9.6e-06 25.8 13.2 0.018 15.4 1.0 2.8 1 1 2 3 3 3 3 C2H2-type zinc ribbon zf-C2H2_aberr PF17017.5 KXS14671.1 - 1.4e-05 25.3 15.1 0.035 14.2 1.1 4.4 4 1 0 4 4 4 2 Aberrant zinc-finger CHORD PF04968.12 KXS14671.1 - 0.024 15.4 13.5 6.5 7.5 0.2 4.4 1 1 4 5 5 5 0 CHORD FOXP-CC PF16159.5 KXS14671.1 - 0.029 15.0 9.0 4.6 7.9 0.1 4.6 2 1 3 5 5 5 0 FOXP coiled-coil domain zf-H2C2_5 PF13909.6 KXS14671.1 - 0.12 12.1 0.3 0.12 12.1 0.3 6.6 8 1 0 8 8 8 0 C2H2-type zinc-finger domain zf-TRAF PF02176.18 KXS14671.1 - 0.37 11.5 16.5 2.4 8.9 0.7 3.7 2 2 1 3 3 3 0 TRAF-type zinc finger zf-met PF12874.7 KXS14671.1 - 1 9.9 0.1 1 9.9 0.1 4.5 5 0 0 5 5 5 0 Zinc-finger of C2H2 type Sel1 PF08238.12 KXS14672.1 - 4.6e-59 195.5 18.2 3.4e-12 46.6 0.0 7.0 7 0 0 7 7 7 6 Sel1 repeat Fib_succ_major PF09603.10 KXS14672.1 - 0.13 12.9 7.6 13 6.4 0.3 3.8 1 1 1 3 3 3 0 Fibrobacter succinogenes major domain (Fib_succ_major) DUF1642 PF07852.11 KXS14672.1 - 9.1 6.9 9.2 7.2 7.2 0.0 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1642) Pkinase PF00069.25 KXS14673.1 - 8.6e-29 100.7 0.0 9.9e-29 100.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS14673.1 - 6.5e-26 91.2 0.0 7.3e-26 91.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXS14673.1 - 0.019 13.8 0.0 0.023 13.5 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase HisG_C PF08029.11 KXS14673.1 - 0.063 13.4 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 HisG, C-terminal domain Kinase-like PF14531.6 KXS14673.1 - 0.24 10.7 0.0 0.29 10.4 0.0 1.3 1 0 0 1 1 1 0 Kinase-like LRR_6 PF13516.6 KXS14674.1 - 2.3e-27 92.7 20.1 1.6e-08 33.9 0.1 6.1 6 1 0 6 6 6 4 Leucine Rich repeat LRR_4 PF12799.7 KXS14674.1 - 1.6e-06 28.3 3.1 0.00065 20.0 0.4 3.0 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KXS14674.1 - 0.0002 21.5 0.0 4.9 8.1 0.0 3.8 4 0 0 4 4 4 2 Leucine Rich Repeat HOASN PF14515.6 KXS14674.1 - 0.0081 16.5 2.6 4.2 7.8 0.3 3.2 2 1 1 3 3 3 1 Haem-oxygenase-associated N-terminal helices LRR_8 PF13855.6 KXS14674.1 - 0.0082 15.9 3.0 3 7.7 1.4 3.4 2 1 0 2 2 2 1 Leucine rich repeat Caskin1-CID PF16600.5 KXS14674.1 - 0.017 15.7 1.1 78 4.0 0.0 4.5 5 0 0 5 5 5 0 Caskin1 CASK-interaction domain Thiolase_C PF02803.18 KXS14674.1 - 0.049 13.3 1.7 6.7 6.4 0.7 3.0 1 1 2 3 3 3 0 Thiolase, C-terminal domain ClpB_D2-small PF10431.9 KXS14674.1 - 0.56 10.3 5.1 41 4.3 0.3 4.1 3 1 1 4 4 4 0 C-terminal, D2-small domain, of ClpB protein HHH_2 PF12826.7 KXS14674.1 - 0.87 9.7 4.9 5.8 7.1 0.2 3.8 2 2 2 4 4 4 0 Helix-hairpin-helix motif T3SS_ExsE PF18286.1 KXS14674.1 - 1.5 8.8 7.7 1e+02 2.9 0.0 4.0 4 0 0 4 4 4 0 Type III secretion system ExsE Cyclin_N PF00134.23 KXS14675.1 - 0.00038 20.2 0.1 0.00061 19.5 0.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain PPI_Ypi1 PF07491.11 KXS14676.1 - 0.4 10.6 2.7 6.5 6.7 0.2 2.6 2 0 0 2 2 2 0 Protein phosphatase inhibitor T5orf172 PF10544.9 KXS14677.1 - 0.00025 21.5 0.1 0.0013 19.2 0.0 2.2 2 0 0 2 2 2 1 T5orf172 domain MUG113 PF13455.6 KXS14677.1 - 0.014 16.1 0.1 0.068 13.8 0.0 2.2 2 0 0 2 2 2 0 Meiotically up-regulated gene 113 TniQ PF06527.11 KXS14677.1 - 0.091 13.5 0.0 0.31 11.8 0.0 1.9 2 0 0 2 2 2 0 TniQ TA0956 PF11513.8 KXS14677.1 - 0.23 11.7 5.2 2 8.7 2.0 2.9 3 0 0 3 3 3 0 Thermoplasma acidophilum protein TA0956 Alanine_zipper PF11839.8 KXS14678.1 - 0.0006 20.1 24.5 0.00098 19.4 24.5 1.3 1 0 0 1 1 1 1 Alanine-zipper, major outer membrane lipoprotein Spt20 PF12090.8 KXS14678.1 - 0.031 13.9 0.4 0.038 13.6 0.4 1.1 1 0 0 1 1 1 0 Spt20 family Selenoprotein_S PF06936.11 KXS14678.1 - 0.096 12.5 5.2 0.13 12.1 5.2 1.1 1 0 0 1 1 1 0 Selenoprotein S (SelS) Etmic-2 PF06670.11 KXS14678.1 - 0.11 11.5 1.7 0.13 11.1 1.7 1.1 1 0 0 1 1 1 0 Microneme protein Etmic-2 SET PF00856.28 KXS14678.1 - 0.12 12.8 0.4 0.13 12.7 0.4 1.1 1 0 0 1 1 1 0 SET domain P22_portal PF16510.5 KXS14678.1 - 0.42 9.1 8.3 0.54 8.8 8.3 1.1 1 0 0 1 1 1 0 Phage P22-like portal protein ERM PF00769.19 KXS14678.1 - 0.46 10.3 15.5 0.64 9.8 15.5 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family EMC3_TMCO1 PF01956.16 KXS14678.1 - 0.51 10.1 3.7 0.72 9.6 3.7 1.5 1 1 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like GTA_holin_3TM PF11351.8 KXS14678.1 - 7.5 7.1 8.5 11 6.6 8.5 1.2 1 0 0 1 1 1 0 Holin of 3TMs, for gene-transfer release Pkinase PF00069.25 KXS14679.1 - 1.2e-24 87.1 0.0 1.3e-24 87.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS14679.1 - 9.1e-19 67.7 0.0 1.1e-18 67.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXS14679.1 - 0.043 12.6 0.0 0.048 12.4 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase YrbL-PhoP_reg PF10707.9 KXS14679.1 - 0.091 12.3 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Kdo PF06293.14 KXS14679.1 - 0.2 11.0 0.0 0.24 10.7 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Fungal_trans PF04082.18 KXS14683.1 - 9.4e-06 24.8 3.3 2e-05 23.8 3.3 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain E3_UbLigase_R4 PF13764.6 KXS14683.1 - 0.02 13.1 0.4 0.022 12.9 0.4 1.0 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase UBR4 Spike_NTD PF16451.5 KXS14683.1 - 0.073 12.4 0.0 0.1 12.0 0.0 1.1 1 0 0 1 1 1 0 Spike glycoprotein N-terminal domain Methyltransf_21 PF05050.12 KXS14684.1 - 2.2e-06 27.8 0.0 3.2e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain BRF1 PF07741.13 KXS14685.1 - 4e-16 59.2 2.5 4e-16 59.2 2.5 2.8 2 1 0 2 2 2 1 Brf1-like TBP-binding domain Dabb PF07876.12 KXS14686.1 - 2.8e-19 69.5 0.0 3.1e-19 69.4 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Methyltransf_22 PF13383.6 KXS14688.1 - 1.5e-16 60.8 0.0 6.2e-16 58.7 0.0 1.9 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_21 PF05050.12 KXS14688.1 - 3.6e-07 30.4 0.0 5.6e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase FkbM domain Kinesin PF00225.23 KXS14690.1 - 1.8e-107 359.1 0.0 2.6e-107 358.6 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KXS14690.1 - 1e-59 200.7 0.0 1.6e-59 200.2 0.0 1.3 1 0 0 1 1 1 1 Microtubule binding LIF_OSM PF01291.17 KXS14690.1 - 0.0047 17.1 0.1 0.0093 16.1 0.1 1.5 1 0 0 1 1 1 1 LIF / OSM family Spc29 PF17082.5 KXS14690.1 - 0.0075 16.1 0.4 0.014 15.3 0.4 1.4 1 0 0 1 1 1 1 Spindle Pole Component 29 YabA PF06156.13 KXS14690.1 - 0.27 11.9 9.4 36 5.1 1.4 4.3 4 1 0 4 4 4 0 Initiation control protein YabA SOAR PF16533.5 KXS14690.1 - 0.42 10.6 4.0 0.59 10.1 2.9 1.9 1 1 0 1 1 1 0 STIM1 Orai1-activating region CENP-F_leu_zip PF10473.9 KXS14690.1 - 0.52 10.3 10.9 1.1 9.3 10.9 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc24 PF08286.11 KXS14690.1 - 1.2 9.5 3.1 25 5.2 1.3 2.5 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Fez1 PF06818.15 KXS14690.1 - 4.3 7.8 11.9 9.9 6.6 11.9 1.6 1 0 0 1 1 1 0 Fez1 Spc7 PF08317.11 KXS14690.1 - 6.8 5.5 12.3 30 3.3 12.3 1.9 1 1 0 1 1 1 0 Spc7 kinetochore protein GAS PF13851.6 KXS14690.1 - 8 5.8 10.1 2.3 7.5 2.0 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Atg14 PF10186.9 KXS14690.1 - 8.4 5.4 8.4 13 4.7 8.4 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Peptidase_M24 PF00557.24 KXS14691.1 - 5.7e-39 134.0 0.1 7.7e-39 133.6 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 TnpW PF14202.6 KXS14691.1 - 0.036 13.9 0.8 1.1 9.1 0.5 2.5 2 0 0 2 2 2 0 Transposon-encoded protein TnpW YL1 PF05764.13 KXS14691.1 - 0.074 13.2 5.3 0.11 12.6 5.3 1.2 1 0 0 1 1 1 0 YL1 nuclear protein NST1 PF13945.6 KXS14691.1 - 0.41 10.7 4.1 0.65 10.1 4.1 1.3 1 0 0 1 1 1 0 Salt tolerance down-regulator NARP1 PF12569.8 KXS14691.1 - 0.52 9.2 4.2 0.93 8.3 4.2 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Zn_clus PF00172.18 KXS14692.1 - 2.7e-05 24.2 5.9 5e-05 23.3 5.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SH3BGR PF04908.15 KXS14693.1 - 1.8e-14 53.7 0.1 2.5e-14 53.2 0.1 1.2 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein Glutaredoxin PF00462.24 KXS14693.1 - 1e-08 35.2 0.0 1.9e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin PgdA_N PF18627.1 KXS14693.1 - 0.02 14.5 0.0 0.025 14.2 0.0 1.1 1 0 0 1 1 1 0 Peptidoglycan GlcNAc deacetylase N-terminal domain Sec1 PF00995.23 KXS14694.1 - 6.4e-112 375.7 0.0 7.6e-112 375.4 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Cu-oxidase_2 PF07731.14 KXS14695.1 - 4.9e-44 149.4 5.6 1.4e-37 128.5 0.3 3.7 3 1 0 3 3 3 3 Multicopper oxidase Cu-oxidase_3 PF07732.15 KXS14695.1 - 3e-42 143.4 4.3 7.2e-42 142.2 0.7 2.9 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.22 KXS14695.1 - 2.8e-33 115.3 0.0 9.8e-33 113.5 0.0 2.0 2 0 0 2 2 2 1 Multicopper oxidase Exostosin PF03016.15 KXS14696.1 - 2.6e-47 161.5 0.0 3.7e-47 161.0 0.0 1.2 1 0 0 1 1 1 1 Exostosin family Exostosin PF03016.15 KXS14697.1 - 7.6e-14 51.6 0.2 9.1e-14 51.4 0.2 1.1 1 0 0 1 1 1 1 Exostosin family Chitin_synth_1 PF01644.17 KXS14698.1 - 1.4e-57 194.3 0.0 1.9e-57 193.8 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.15 KXS14698.1 - 1.7e-20 73.1 0.2 2.6e-15 56.0 0.0 2.4 2 0 0 2 2 2 2 Chitin synthase Chitin_synth_1N PF08407.11 KXS14698.1 - 6.8e-17 61.2 0.0 1.7e-16 59.9 0.0 1.7 1 0 0 1 1 1 1 Chitin synthase N-terminal Glyco_trans_2_3 PF13632.6 KXS14698.1 - 2.1e-11 44.1 0.3 2.1e-11 44.1 0.3 2.7 3 1 0 3 3 3 1 Glycosyl transferase family group 2 Flavoprotein PF02441.19 KXS14699.1 - 1.2e-47 161.7 0.0 1.4e-47 161.4 0.0 1.1 1 0 0 1 1 1 1 Flavoprotein LysR_substrate PF03466.20 KXS14699.1 - 0.034 13.5 0.1 0.06 12.7 0.1 1.3 1 0 0 1 1 1 0 LysR substrate binding domain Josephin PF02099.17 KXS14700.1 - 1.2e-37 129.5 0.0 1.9e-37 128.9 0.0 1.2 1 0 0 1 1 1 1 Josephin UIM PF02809.20 KXS14700.1 - 1.1e-09 37.6 28.4 0.074 13.0 1.1 5.8 5 0 0 5 5 5 5 Ubiquitin interaction motif ParD_antitoxin PF03693.14 KXS14700.1 - 0.086 13.3 0.1 0.24 11.8 0.1 1.7 1 0 0 1 1 1 0 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH PikAIV_N PF18605.1 KXS14700.1 - 1.7 8.3 5.4 5.3 6.7 0.2 3.3 3 0 0 3 3 3 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain TAFII28 PF04719.14 KXS14701.1 - 0.025 14.7 0.7 1.8 8.7 0.0 2.2 2 0 0 2 2 2 0 hTAFII28-like protein conserved region Endosulfine PF04667.17 KXS14703.1 - 4.6e-21 74.7 0.0 7.5e-21 74.1 0.0 1.3 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region ECH_1 PF00378.20 KXS14704.1 - 5.2e-24 84.9 0.0 1.2e-23 83.7 0.0 1.5 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXS14704.1 - 8.4e-08 32.1 0.0 1.3e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase DUF2236 PF09995.9 KXS14705.1 - 4.2e-09 37.0 0.2 5.2e-09 36.6 0.2 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) TP53IP5 PF15331.6 KXS14706.1 - 0.13 12.4 0.0 0.14 12.2 0.0 1.1 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 Acetyltransf_1 PF00583.25 KXS14707.1 - 2.7e-07 30.9 0.0 4e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 KXS14707.1 - 3.9e-05 23.6 0.0 7.5e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 KXS14707.1 - 8.5e-05 23.3 0.0 0.00014 22.5 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KXS14707.1 - 0.00055 19.6 0.0 0.00092 18.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXS14707.1 - 0.00075 19.9 0.0 0.0012 19.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain TPP_enzyme_N PF02776.18 KXS14708.1 - 4.3e-47 159.9 4.3 1.3e-46 158.4 4.3 1.8 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KXS14708.1 - 1.8e-23 83.0 0.7 3.5e-23 82.1 0.2 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KXS14708.1 - 8.6e-12 45.0 0.0 2e-11 43.8 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain POR_N PF01855.19 KXS14708.1 - 0.0033 17.2 2.0 0.0064 16.3 2.0 1.4 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg ACP_syn_III PF08545.10 KXS14708.1 - 0.082 12.8 2.2 0.56 10.1 0.3 3.0 2 1 1 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III FOLN PF09289.10 KXS14709.1 - 0.05 13.8 0.2 0.085 13.1 0.2 1.4 1 0 0 1 1 1 0 Follistatin/Osteonectin-like EGF domain SH3_9 PF14604.6 KXS14710.1 - 1.3e-05 24.9 0.0 2.8e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain CBM_21 PF03370.13 KXS14711.1 - 1.5e-06 28.3 0.0 2.6e-06 27.6 0.0 1.6 1 1 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) Methyltransf_24 PF13578.6 KXS14712.1 - 4.7e-07 30.8 0.1 1.5e-06 29.2 0.0 1.9 3 0 0 3 3 3 1 Methyltransferase domain Beta-lactamase PF00144.24 KXS14713.1 - 1.6e-49 168.9 0.0 2.1e-49 168.5 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase Beta-lactamase2 PF13354.6 KXS14713.1 - 0.11 12.1 0.0 2.2 7.9 0.0 2.3 2 1 0 2 2 2 0 Beta-lactamase enzyme family zf-RING_UBOX PF13445.6 KXS14714.1 - 3.6e-09 36.5 13.3 1.7e-08 34.3 8.7 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KXS14714.1 - 5.8e-09 35.6 6.5 5.8e-09 35.6 6.5 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXS14714.1 - 1.8e-08 34.1 9.5 7.7e-08 32.1 9.7 1.8 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXS14714.1 - 4.7e-08 33.2 11.6 1.1e-07 32.0 11.6 1.6 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 KXS14714.1 - 3.3e-07 30.4 13.1 2.9e-06 27.3 13.5 2.1 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 KXS14714.1 - 1.2e-06 28.2 11.4 7.1e-06 25.8 11.4 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXS14714.1 - 7.5e-06 25.8 7.8 1.3e-05 25.1 7.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KXS14714.1 - 0.024 14.5 14.3 0.5 10.3 14.3 2.3 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 KXS14714.1 - 0.042 13.6 10.9 0.042 13.6 10.9 1.9 2 0 0 2 2 2 0 RING-like zinc finger zf-Nse PF11789.8 KXS14714.1 - 0.084 12.7 5.9 0.16 11.8 5.9 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Zn-C2H2_12 PF18112.1 KXS14714.1 - 0.56 10.7 4.2 9 6.9 0.3 2.5 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zf-RING_6 PF14835.6 KXS14714.1 - 0.83 9.6 7.6 0.16 11.9 4.0 1.6 2 0 0 2 2 2 0 zf-RING of BARD1-type protein DUF3824 PF12868.7 KXS14714.1 - 8.1 7.1 9.0 1.1 9.9 4.8 1.6 2 0 0 2 2 2 0 Domain of unknwon function (DUF3824) GATase PF00117.28 KXS14716.1 - 0.012 15.4 0.0 1.3 8.7 0.0 2.1 1 1 1 2 2 2 0 Glutamine amidotransferase class-I NAD_binding_10 PF13460.6 KXS14717.1 - 2.9e-17 63.1 1.1 4.9e-17 62.4 1.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KXS14717.1 - 3e-16 59.7 0.3 3.9e-16 59.3 0.3 1.1 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 KXS14717.1 - 3.2e-06 26.8 0.1 9e-06 25.3 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KXS14717.1 - 0.00061 19.0 0.6 0.0016 17.6 0.1 1.9 2 1 0 2 2 2 1 RmlD substrate binding domain TrkA_N PF02254.18 KXS14717.1 - 0.0012 19.0 0.2 0.0042 17.3 0.0 2.0 1 1 1 2 2 2 1 TrkA-N domain adh_short PF00106.25 KXS14717.1 - 0.0055 16.2 0.9 0.021 14.3 0.1 2.0 2 0 0 2 2 2 1 short chain dehydrogenase GDP_Man_Dehyd PF16363.5 KXS14717.1 - 0.0084 15.5 0.1 0.02 14.3 0.1 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase DapB_N PF01113.20 KXS14717.1 - 0.0095 16.1 0.1 0.044 13.9 0.0 2.0 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.19 KXS14717.1 - 0.017 14.5 0.0 0.037 13.4 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_4 PF07993.12 KXS14717.1 - 0.055 12.6 0.1 0.1 11.7 0.1 1.4 1 0 0 1 1 1 0 Male sterility protein zf-C3HC4_2 PF13923.6 KXS14718.1 - 8.6e-09 35.1 5.5 8.6e-09 35.1 5.5 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXS14718.1 - 4.2e-08 32.9 8.6 6.9e-08 32.2 8.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KXS14718.1 - 5.3e-08 32.9 5.3 5.3e-08 32.9 5.3 1.7 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 KXS14718.1 - 4.7e-07 29.7 12.3 9.3e-07 28.8 12.3 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KXS14718.1 - 6.2e-06 26.0 4.7 1.3e-05 25.0 4.7 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXS14718.1 - 7.2e-06 26.2 12.9 1.4e-05 25.3 12.9 1.5 1 1 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KXS14718.1 - 0.00015 21.7 5.6 0.00042 20.2 5.8 1.6 1 1 1 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.7 KXS14718.1 - 0.77 10.1 12.2 2.8 8.3 12.2 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger domain Atg14 PF10186.9 KXS14721.1 - 2.5 7.1 10.0 7.7 5.5 0.3 2.2 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4407 PF14362.6 KXS14721.1 - 7.6 5.8 11.3 3.3 7.0 4.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Rootletin PF15035.6 KXS14721.1 - 8.5 6.4 16.9 0.42 10.6 10.0 2.1 3 0 0 3 3 3 0 Ciliary rootlet component, centrosome cohesion CN_hydrolase PF00795.22 KXS14723.1 - 2.2e-07 30.5 0.0 4e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase DCB PF16213.5 KXS14725.1 - 0.22 11.2 4.7 0.44 10.2 4.7 1.6 1 1 0 1 1 1 0 Dimerisation and cyclophilin-binding domain of Mon2 MFS_1 PF07690.16 KXS14726.1 - 4.3e-25 88.4 32.4 2.6e-20 72.6 10.9 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KXS14726.1 - 1.6e-06 27.0 16.2 1.7e-05 23.6 4.2 2.9 2 1 1 3 3 3 3 MFS/sugar transport protein Sugar_tr PF00083.24 KXS14726.1 - 0.00011 21.3 14.6 0.00086 18.3 5.3 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter DUF3846 PF12957.7 KXS14727.1 - 5.5e-05 23.4 0.0 0.0001 22.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3846) GFO_IDH_MocA PF01408.22 KXS14728.1 - 1.8e-21 77.2 0.0 2.8e-21 76.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.24 KXS14728.1 - 0.022 15.2 0.0 0.038 14.4 0.0 1.3 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DUF4532 PF15046.6 KXS14728.1 - 9 5.4 8.6 0.13 11.4 1.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4532) Lipase_GDSL PF00657.22 KXS14729.1 - 0.00091 19.2 0.0 0.0039 17.2 0.0 1.8 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase SSrecog PF03531.14 KXS14730.1 - 7e-25 86.7 0.0 1.8e-24 85.4 0.0 1.8 1 0 0 1 1 1 1 Structure-specific recognition protein (SSRP1) HMG_box PF00505.19 KXS14730.1 - 1.1e-20 73.7 0.4 2e-20 73.0 0.4 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box Rtt106 PF08512.12 KXS14730.1 - 3.7e-16 59.3 0.0 7e-16 58.4 0.0 1.5 1 0 0 1 1 1 1 Histone chaperone Rttp106-like POB3_N PF17292.2 KXS14730.1 - 2.1e-13 50.5 0.0 5.6e-11 42.7 0.0 2.6 2 0 0 2 2 2 1 POB3-like N-terminal PH domain HMG_box_2 PF09011.10 KXS14730.1 - 2.3e-12 47.3 0.3 5.1e-12 46.2 0.3 1.6 1 0 0 1 1 1 1 HMG-box domain K_channel_TID PF07941.11 KXS14730.1 - 0.28 11.7 12.0 0.12 12.9 8.3 2.3 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain GyrI-like PF06445.15 KXS14731.1 - 3.6e-07 30.6 0.3 4.2e-07 30.4 0.3 1.3 1 1 0 1 1 1 1 GyrI-like small molecule binding domain Aminotran_4 PF01063.19 KXS14734.1 - 2.1e-32 112.8 0.0 3e-32 112.3 0.0 1.2 1 0 0 1 1 1 1 Amino-transferase class IV NTP_transf_9 PF04248.12 KXS14735.1 - 2.9e-30 104.0 0.6 3.3e-30 103.8 0.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF427) Peptidase_A4 PF01828.17 KXS14735.1 - 0.11 12.0 2.2 0.64 9.4 2.2 1.9 1 1 0 1 1 1 0 Peptidase A4 family FAD_binding_4 PF01565.23 KXS14736.1 - 7.9e-41 139.1 0.0 1.3e-40 138.3 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.19 KXS14736.1 - 2.3e-33 115.9 0.2 4.3e-33 115.0 0.2 1.4 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain ANF_receptor PF01094.28 KXS14736.1 - 0.0049 16.0 0.0 0.0079 15.3 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Ras PF00071.22 KXS14737.1 - 4.4e-56 189.0 0.0 5.1e-56 188.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXS14737.1 - 4.8e-21 75.2 0.0 6.8e-21 74.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXS14737.1 - 3.9e-07 29.7 0.0 7.3e-07 28.8 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KXS14737.1 - 0.00093 18.7 0.0 0.0014 18.1 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Alpha-amylase PF00128.24 KXS14738.1 - 0.00021 21.0 0.0 0.00023 20.9 0.0 1.0 1 0 0 1 1 1 1 Alpha amylase, catalytic domain NPH3 PF03000.14 KXS14739.1 - 0.045 13.4 0.0 0.07 12.8 0.0 1.2 1 0 0 1 1 1 0 NPH3 family Gpr1_Fun34_YaaH PF01184.19 KXS14740.1 - 7e-19 68.3 21.6 9.4e-19 67.8 21.6 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family MlaA PF04333.13 KXS14740.1 - 0.16 11.6 0.4 0.26 11.0 0.4 1.3 1 0 0 1 1 1 0 MlaA lipoprotein L51_S25_CI-B8 PF05047.16 KXS14741.1 - 0.12 12.3 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Ufd2P_core PF10408.9 KXS14742.1 - 5.4e-169 563.8 0.0 6.5e-169 563.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 KXS14742.1 - 6.4e-21 74.3 0.2 1.4e-20 73.2 0.2 1.6 1 0 0 1 1 1 1 U-box domain Glutaredoxin PF00462.24 KXS14743.1 - 1.4e-14 54.1 0.4 1e-12 48.0 0.0 2.2 2 0 0 2 2 2 2 Glutaredoxin NPH3 PF03000.14 KXS14745.1 - 0.13 11.9 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 NPH3 family RAM PF15320.6 KXS14745.1 - 4.6 7.9 8.2 2.9 8.6 0.1 2.8 2 0 0 2 2 2 0 mRNA cap methylation, RNMT-activating mini protein NAD_binding_10 PF13460.6 KXS14746.1 - 2.9e-18 66.4 0.9 4.5e-18 65.8 0.9 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KXS14746.1 - 1e-17 64.5 0.4 1.3e-17 64.1 0.4 1.1 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 KXS14746.1 - 2.3e-05 24.0 0.1 4.5e-05 23.0 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXS14746.1 - 0.00013 21.5 0.0 0.00029 20.4 0.0 1.6 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KXS14746.1 - 0.0003 20.0 0.1 0.00048 19.3 0.1 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain TrkA_N PF02254.18 KXS14746.1 - 0.0031 17.8 0.1 0.012 15.9 0.0 1.9 1 1 1 2 2 2 1 TrkA-N domain F420_oxidored PF03807.17 KXS14746.1 - 0.0043 17.6 0.1 0.25 12.0 0.0 2.9 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent DapB_N PF01113.20 KXS14746.1 - 0.011 15.9 0.4 0.12 12.4 0.1 2.6 3 0 0 3 3 3 0 Dihydrodipicolinate reductase, N-terminus CysA_C_terminal PF17850.1 KXS14746.1 - 0.015 15.9 0.1 1.2 9.7 0.0 2.7 2 0 0 2 2 2 0 CysA C-terminal regulatory domain NAD_binding_4 PF07993.12 KXS14746.1 - 0.063 12.4 0.2 0.1 11.8 0.2 1.3 1 0 0 1 1 1 0 Male sterility protein Ldh_1_N PF00056.23 KXS14746.1 - 0.085 13.0 0.1 0.33 11.0 0.0 2.1 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.24 KXS14746.1 - 0.089 13.2 0.6 0.24 11.8 0.2 2.1 1 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.25 KXS14748.1 - 6.7e-35 120.3 0.2 1.7e-34 119.0 0.1 1.7 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXS14748.1 - 7.2e-30 104.3 0.1 7.9e-28 97.6 0.0 2.3 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXS14748.1 - 2.9e-08 33.9 0.2 7e-08 32.6 0.2 1.6 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.10 KXS14748.1 - 0.15 11.4 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 KXS14748.1 - 0.16 11.4 0.2 0.79 9.1 0.0 2.1 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family TMF_DNA_bd PF12329.8 KXS14749.1 - 0.047 13.7 3.6 0.054 13.5 3.6 1.1 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Nebulin PF00880.18 KXS14749.1 - 0.56 10.2 2.9 1.1 9.2 0.2 2.3 2 1 1 3 3 3 0 Nebulin repeat BTB PF00651.31 KXS14750.1 - 0.00014 22.0 0.0 0.00044 20.5 0.0 1.9 2 1 0 2 2 2 1 BTB/POZ domain BTB PF00651.31 KXS14751.1 - 4.6e-07 30.0 0.0 8e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KXS14752.1 - 9.5e-06 25.8 0.0 1.8e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KXS14754.1 - 5.2e-07 29.9 0.0 8.7e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2 PF00096.26 KXS14756.1 - 6.5e-17 61.0 9.6 1e-05 25.7 0.8 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXS14756.1 - 1.9e-12 46.9 8.1 0.00096 19.8 0.4 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KXS14756.1 - 1.1e-07 32.0 9.8 0.019 15.4 0.7 3.4 3 0 0 3 3 3 3 Zinc-finger double domain zf-met PF12874.7 KXS14756.1 - 2.6e-05 24.4 1.6 0.11 13.0 0.4 3.4 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2HE PF16278.5 KXS14756.1 - 0.00025 21.5 1.0 0.2 12.1 0.0 2.8 2 1 0 2 2 2 1 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_3rep PF18868.1 KXS14756.1 - 0.0005 20.8 3.7 0.27 11.9 0.3 3.5 1 1 2 3 3 3 1 Zinc finger C2H2-type, 3 repeats zf-C2H2_jaz PF12171.8 KXS14756.1 - 0.0019 18.5 0.3 0.37 11.1 0.0 3.1 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KXS14756.1 - 0.0023 17.9 5.2 0.23 11.5 0.1 3.4 3 0 0 3 3 3 1 C2H2-type zinc finger ADK_lid PF05191.14 KXS14756.1 - 0.0097 15.9 2.6 0.078 13.0 0.3 2.7 2 0 0 2 2 2 1 Adenylate kinase, active site lid zf-BED PF02892.15 KXS14756.1 - 0.01 15.8 6.2 4.6 7.3 0.6 3.3 1 1 1 2 2 2 0 BED zinc finger zf-C2H2_11 PF16622.5 KXS14756.1 - 0.012 15.3 7.5 1.2 9.0 0.2 3.4 3 0 0 3 3 3 0 zinc-finger C2H2-type ADD_ATRX PF17981.1 KXS14756.1 - 0.045 13.6 1.4 0.085 12.7 0.4 1.9 2 0 0 2 2 2 0 Cysteine Rich ADD domain TF_Zn_Ribbon PF08271.12 KXS14756.1 - 0.048 13.2 1.8 0.25 10.9 0.1 2.6 2 0 0 2 2 2 0 TFIIB zinc-binding zf-Di19 PF05605.12 KXS14756.1 - 0.062 13.6 6.2 0.16 12.3 0.5 2.7 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_8 PF15909.5 KXS14756.1 - 0.071 13.4 2.0 0.31 11.3 0.3 2.4 1 1 1 2 2 2 0 C2H2-type zinc ribbon Zn-ribbon_8 PF09723.10 KXS14756.1 - 0.089 12.9 5.1 6.1 7.0 0.5 2.9 2 0 0 2 2 2 0 Zinc ribbon domain zf_UBZ PF18439.1 KXS14756.1 - 0.15 11.7 2.1 14 5.4 0.1 3.1 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-AN1 PF01428.16 KXS14756.1 - 0.31 11.2 5.2 9.4 6.5 0.1 3.1 3 0 0 3 3 3 0 AN1-like Zinc finger DZR PF12773.7 KXS14756.1 - 0.65 10.1 3.3 22 5.2 3.3 2.5 1 1 0 1 1 1 0 Double zinc ribbon Elf1 PF05129.13 KXS14756.1 - 0.75 9.9 3.6 0.38 10.8 0.6 1.9 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like zf-RRN7 PF11781.8 KXS14756.1 - 0.99 9.1 5.2 5.6 6.7 0.1 3.1 3 0 0 3 3 3 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 OrfB_Zn_ribbon PF07282.11 KXS14756.1 - 1 9.3 7.3 2.1 8.3 0.4 3.6 2 1 2 4 4 4 0 Putative transposase DNA-binding domain zf-Mss51 PF13824.6 KXS14756.1 - 1.4 9.1 4.1 20 5.3 3.9 2.8 1 1 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 C1_1 PF00130.22 KXS14756.1 - 6.5 6.7 6.7 24 4.9 0.6 2.6 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) FYDLN_acid PF09538.10 KXS14756.1 - 8.2 7.2 10.5 3.2 8.5 0.4 4.3 2 2 2 4 4 4 0 Protein of unknown function (FYDLN_acid) MFS_1 PF07690.16 KXS14757.1 - 2.9e-05 23.1 8.6 3.2e-05 23.0 8.6 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily LSM PF01423.22 KXS14758.1 - 7.8e-17 60.7 0.4 1e-16 60.4 0.4 1.1 1 0 0 1 1 1 1 LSM domain DUF2599 PF10783.9 KXS14759.1 - 0.11 13.2 0.0 0.28 11.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2599) Glyco_hydro_16 PF00722.21 KXS14760.1 - 5.1e-27 94.5 4.1 7.7e-27 93.9 4.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Dehydrin PF00257.19 KXS14760.1 - 0.027 15.0 1.2 0.071 13.7 1.2 1.8 1 0 0 1 1 1 0 Dehydrin RCR PF12273.8 KXS14760.1 - 1.1 9.9 6.9 0.85 10.3 0.8 3.4 3 1 0 3 3 3 0 Chitin synthesis regulation, resistance to Congo red MSC PF09402.10 KXS14761.1 - 0.028 13.9 0.4 0.045 13.2 0.4 1.5 1 1 0 1 1 1 0 Man1-Src1p-C-terminal domain ADH_N PF08240.12 KXS14762.1 - 8.8e-30 102.8 4.4 2.3e-29 101.5 4.4 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXS14762.1 - 1.1e-24 86.8 3.2 1.7e-24 86.2 3.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXS14762.1 - 1.1e-06 29.7 0.3 1.8e-06 29.0 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TrkA_N PF02254.18 KXS14762.1 - 0.1 12.9 0.1 0.2 11.9 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain IGFBP PF00219.18 KXS14762.1 - 9.6 7.0 9.1 2.5 8.8 2.6 2.7 3 0 0 3 3 3 0 Insulin-like growth factor binding protein Abhydrolase_3 PF07859.13 KXS14765.1 - 1.7e-44 152.2 0.0 2.4e-44 151.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KXS14765.1 - 1.7e-15 56.9 0.1 5.6e-15 55.2 0.1 1.6 1 1 0 1 1 1 1 Carboxylesterase family Say1_Mug180 PF10340.9 KXS14765.1 - 4.9e-05 22.3 0.0 9.6e-05 21.4 0.0 1.3 1 1 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 KXS14765.1 - 0.0075 15.8 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family AXE1 PF05448.12 KXS14765.1 - 0.015 14.0 0.0 0.52 8.9 0.0 2.1 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Ig_Tie2_1 PF10430.9 KXS14765.1 - 0.19 12.2 0.0 0.36 11.3 0.0 1.4 1 0 0 1 1 1 0 Tie-2 Ig-like domain 1 Ras PF00071.22 KXS14766.1 - 2.4e-57 193.0 0.0 2.9e-57 192.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXS14766.1 - 2.3e-35 121.4 0.0 3.1e-35 121.0 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXS14766.1 - 3.8e-16 59.0 0.0 5e-16 58.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KXS14766.1 - 5.2e-06 26.0 0.0 6.4e-06 25.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KXS14766.1 - 3.3e-05 23.9 0.0 4.9e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KXS14766.1 - 0.00028 20.5 0.0 0.00049 19.7 0.0 1.4 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KXS14766.1 - 0.00028 20.8 0.0 0.41 10.5 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 KXS14766.1 - 0.0014 19.0 0.0 0.0019 18.6 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain TAL_FSA PF00923.19 KXS14768.1 - 4.5e-94 315.0 0.0 5.1e-94 314.8 0.0 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase zf-CCHC_2 PF13696.6 KXS14769.1 - 3.7e-20 71.4 15.5 1.3e-10 40.8 6.3 2.6 2 0 0 2 2 2 2 Zinc knuckle CwfJ_C_1 PF04677.15 KXS14769.1 - 1.3e-19 70.3 0.0 2.4e-19 69.4 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 zf-CCHC PF00098.23 KXS14769.1 - 3.8e-09 36.2 8.7 9.6e-05 22.3 1.4 2.6 2 0 0 2 2 2 2 Zinc knuckle CwfJ_C_2 PF04676.14 KXS14769.1 - 8.6e-06 26.6 0.0 1.7e-05 25.6 0.0 1.5 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 zf-CCHC_3 PF13917.6 KXS14769.1 - 0.0034 17.3 3.1 0.64 10.0 0.2 2.6 2 0 0 2 2 2 2 Zinc knuckle CLIP1_ZNF PF16641.5 KXS14769.1 - 2.3 8.2 5.7 9.7 6.2 0.5 2.5 2 0 0 2 2 2 0 CLIP1 zinc knuckle zf-CCHC_4 PF14392.6 KXS14769.1 - 8.3 6.2 5.6 39 4.1 0.5 2.5 2 0 0 2 2 2 0 Zinc knuckle ECH_1 PF00378.20 KXS14770.1 - 1.1e-31 110.1 0.0 1.3e-31 109.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXS14770.1 - 2.5e-22 79.8 0.0 3e-22 79.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase zf-RING_5 PF14634.6 KXS14772.1 - 0.0011 18.9 0.5 0.0026 17.7 0.5 1.6 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 KXS14772.1 - 0.0011 19.3 3.9 0.0035 17.6 3.9 1.7 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KXS14772.1 - 0.0014 18.4 1.6 0.017 14.9 0.1 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXS14772.1 - 0.01 15.9 1.2 0.041 13.9 0.3 2.0 1 1 1 2 2 2 0 RING-type zinc-finger zf-RING_11 PF17123.5 KXS14772.1 - 0.012 15.3 1.4 0.012 15.3 1.4 1.8 2 0 0 2 2 2 0 RING-like zinc finger zf-rbx1 PF12678.7 KXS14772.1 - 0.035 14.4 5.7 0.27 11.5 5.7 2.0 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KXS14772.1 - 0.062 13.4 1.1 0.82 9.8 1.1 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger PHD PF00628.29 KXS14772.1 - 0.11 12.4 2.4 1.3 9.0 2.3 2.1 1 1 1 2 2 2 0 PHD-finger zf-C3HC4 PF00097.25 KXS14772.1 - 0.13 12.2 3.6 1.1 9.2 3.9 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-PHD-like PF15446.6 KXS14772.1 - 0.14 11.8 1.8 0.85 9.2 2.0 1.8 1 1 1 2 2 2 0 PHD/FYVE-zinc-finger like domain CitMHS_2 PF16980.5 KXS14773.1 - 5.1e-12 45.2 0.7 2e-08 33.3 0.1 2.1 2 0 0 2 2 2 2 Putative citrate transport Abhydrolase_1 PF00561.20 KXS14774.1 - 3e-23 82.8 0.0 5.2e-23 82.0 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXS14774.1 - 1.8e-20 74.5 1.9 2.9e-20 73.8 1.9 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXS14774.1 - 5.7e-08 32.3 0.0 1.4e-07 31.0 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DSBA PF01323.20 KXS14775.1 - 1.2e-20 74.2 0.0 3e-20 72.8 0.0 1.6 1 1 0 1 1 1 1 DSBA-like thioredoxin domain DUF2774 PF11242.8 KXS14775.1 - 0.026 14.7 0.2 0.063 13.5 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2774) Thioredoxin_5 PF13743.6 KXS14775.1 - 0.066 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin YTH PF04146.15 KXS14776.1 - 5.8e-40 137.0 0.0 9.7e-40 136.2 0.0 1.4 1 0 0 1 1 1 1 YT521-B-like domain CBS PF00571.28 KXS14778.1 - 2.3e-21 76.0 1.3 0.0024 18.3 0.1 5.7 5 1 0 5 5 5 5 CBS domain Lipase_3 PF01764.25 KXS14779.1 - 1.5e-17 63.8 0.0 2.6e-17 63.0 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) C2 PF00168.30 KXS14779.1 - 5.7e-06 26.6 0.0 1.2e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 C2 domain DUF218 PF02698.17 KXS14780.1 - 0.11 12.5 0.0 0.57 10.2 0.0 2.0 1 1 0 1 1 1 0 DUF218 domain SNase PF00565.17 KXS14781.1 - 1.2e-46 157.6 0.1 8.4e-15 55.2 0.0 5.7 5 1 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.24 KXS14781.1 - 1.9e-20 73.1 0.0 3.8e-20 72.1 0.0 1.5 1 0 0 1 1 1 1 Tudor domain Agenet PF05641.12 KXS14781.1 - 0.016 15.7 0.5 0.17 12.4 0.0 2.9 3 0 0 3 3 3 0 Agenet domain LBR_tudor PF09465.10 KXS14781.1 - 0.089 12.6 0.1 0.2 11.5 0.1 1.6 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain zf-MYND PF01753.18 KXS14782.1 - 1.8e-06 27.9 1.3 3.4e-06 27.0 1.3 1.5 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KXS14782.1 - 0.011 16.1 1.3 0.019 15.2 1.3 1.5 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding zf-HIT PF04438.16 KXS14782.1 - 0.11 12.3 0.3 0.11 12.3 0.3 1.9 3 0 0 3 3 3 0 HIT zinc finger DUF1931 PF09123.11 KXS14783.1 - 0.13 12.4 0.0 0.19 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1931) Peptidase_C14 PF00656.22 KXS14785.1 - 1.7e-52 178.9 0.0 2.1e-52 178.6 0.0 1.0 1 0 0 1 1 1 1 Caspase domain Peptidase_C13 PF01650.18 KXS14785.1 - 0.017 14.7 0.2 2.2 7.8 0.0 2.6 1 1 1 2 2 2 0 Peptidase C13 family Grg1 PF11034.8 KXS14785.1 - 0.065 13.5 0.3 0.13 12.5 0.3 1.5 1 0 0 1 1 1 0 Glucose-repressible protein Grg1 PMSR PF01625.21 KXS14786.1 - 9.3e-06 25.9 0.2 0.00033 20.9 0.2 2.1 1 1 0 1 1 1 1 Peptide methionine sulfoxide reductase p450 PF00067.22 KXS14789.1 - 1.4e-67 228.5 0.0 1.9e-67 228.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KXS14790.1 - 5e-79 266.2 0.0 7.7e-79 265.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 eIF-3c_N PF05470.12 KXS14790.1 - 0.15 10.4 0.1 0.21 9.9 0.1 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Glyco_transf_15 PF01793.16 KXS14791.1 - 2e-98 329.7 5.2 2.2e-98 329.5 5.2 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase F-box PF00646.33 KXS14794.1 - 0.034 14.1 1.8 0.11 12.5 0.2 2.4 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.7 KXS14794.1 - 0.035 14.0 0.1 0.087 12.7 0.1 1.7 1 0 0 1 1 1 0 F-box-like F-box_4 PF15966.5 KXS14794.1 - 0.046 13.6 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 F-box SH3_1 PF00018.28 KXS14796.1 - 2.2e-06 27.2 0.0 4.4e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KXS14796.1 - 3.6e-06 26.7 0.1 8.3e-06 25.6 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain ABM PF03992.16 KXS14797.1 - 3.9e-12 46.1 0.0 4.6e-12 45.9 0.0 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase GxGYxYP_N PF16216.5 KXS14797.1 - 0.096 12.9 0.0 0.11 12.6 0.0 1.1 1 0 0 1 1 1 0 GxGYxY sequence motif in domain of unknown function N-terminal PAP2 PF01569.21 KXS14799.1 - 4.4e-13 49.2 8.0 5.2e-13 48.9 6.6 1.9 1 1 0 1 1 1 1 PAP2 superfamily Phage_holin_3_1 PF05106.12 KXS14799.1 - 0.097 13.1 0.5 0.22 12.0 0.5 1.5 1 0 0 1 1 1 0 Phage holin family (Lysis protein S) ABC2_membrane_5 PF13346.6 KXS14799.1 - 0.46 10.0 8.3 0.47 10.0 4.2 2.0 2 0 0 2 2 2 0 ABC-2 family transporter protein AA_permease_C PF13906.6 KXS14799.1 - 1.1 9.3 7.6 0.36 10.9 2.2 2.4 1 1 1 2 2 2 0 C-terminus of AA_permease DUF1129 PF06570.11 KXS14799.1 - 7.4 6.0 6.0 2.6 7.5 0.9 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1129) CsrA PF02599.16 KXS14800.1 - 0.15 12.0 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Global regulator protein family Sod_Cu PF00080.20 KXS14801.1 - 5.7e-50 169.2 9.4 6.6e-50 169.0 9.4 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) BppL_N PF18338.1 KXS14801.1 - 0.0042 16.8 1.7 0.1 12.4 0.1 3.1 3 0 0 3 3 3 1 Lower baseplate protein N-terminal domain SH3_1 PF00018.28 KXS14802.1 - 8.9e-05 22.0 0.0 0.00015 21.3 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KXS14802.1 - 0.00086 19.1 0.0 0.0019 18.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain AJAP1_PANP_C PF15298.6 KXS14802.1 - 0.0029 17.8 0.3 0.0029 17.8 0.3 1.5 2 0 0 2 2 2 1 AJAP1/PANP C-terminus PsiB PF06290.11 KXS14802.1 - 0.018 14.5 0.0 0.029 13.8 0.0 1.3 1 0 0 1 1 1 0 Plasmid SOS inhibition protein (PsiB) SPX PF03105.19 KXS14804.1 - 0.17 11.8 1.2 0.22 11.4 1.2 1.2 1 0 0 1 1 1 0 SPX domain Cas_Cas2CT1978 PF09707.10 KXS14807.1 - 0.09 12.9 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cas2CT1978) SH3_1 PF00018.28 KXS14808.1 - 4.5e-07 29.4 0.0 1.3e-06 27.9 0.0 1.8 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KXS14808.1 - 0.0005 19.9 2.0 0.0086 15.9 0.1 3.1 2 1 1 3 3 3 1 Variant SH3 domain Isochorismatase PF00857.20 KXS14810.1 - 6.2e-20 72.1 0.0 7.7e-20 71.8 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family SH3_9 PF14604.6 KXS14811.1 - 7.5e-05 22.5 1.1 0.00013 21.7 0.1 2.1 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 KXS14811.1 - 0.002 17.7 0.0 0.0044 16.6 0.0 1.7 1 0 0 1 1 1 1 SH3 domain PB1 PF00564.24 KXS14813.1 - 0.001 19.0 0.0 0.0018 18.1 0.0 1.4 1 0 0 1 1 1 1 PB1 domain MRI PF15325.6 KXS14813.1 - 0.94 10.6 3.3 1.9 9.6 2.3 2.0 2 0 0 2 2 2 0 Modulator of retrovirus infection zf-C2H2 PF00096.26 KXS14815.1 - 1.3e-07 31.7 5.9 0.00014 22.1 0.3 2.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXS14815.1 - 5.6e-06 26.7 4.3 0.014 16.2 0.3 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KXS14815.1 - 0.00021 21.6 1.4 0.0039 17.5 0.2 2.3 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_11 PF16622.5 KXS14815.1 - 0.0029 17.3 0.8 0.0057 16.4 0.8 1.5 1 0 0 1 1 1 1 zinc-finger C2H2-type zf-C2H2_aberr PF17017.5 KXS14815.1 - 0.0048 17.1 0.3 0.0094 16.1 0.3 1.4 1 1 0 1 1 1 1 Aberrant zinc-finger zf-C2H2_6 PF13912.6 KXS14815.1 - 0.62 10.1 3.5 2.9 8.0 0.3 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger SH3_9 PF14604.6 KXS14817.1 - 8.8e-06 25.5 0.0 3e-05 23.8 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 KXS14817.1 - 0.0046 16.5 0.0 0.0076 15.8 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KXS14817.1 - 0.12 12.0 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Variant SH3 domain PB1 PF00564.24 KXS14818.1 - 0.0035 17.3 0.4 0.0035 17.3 0.4 1.1 1 0 0 1 1 1 1 PB1 domain Lysine_decarbox PF03641.14 KXS14818.1 - 0.063 13.4 0.0 0.063 13.4 0.0 1.1 1 0 0 1 1 1 0 Possible lysine decarboxylase Chalcone_2 PF16035.5 KXS14819.1 - 2e-27 96.3 0.0 4.3e-27 95.2 0.0 1.5 1 1 0 1 1 1 1 Chalcone isomerase like Chalcone_3 PF16036.5 KXS14819.1 - 3.4e-06 27.3 0.0 0.018 15.1 0.0 2.1 1 1 1 2 2 2 2 Chalcone isomerase-like Cyclin_N PF00134.23 KXS14820.1 - 1.4e-05 24.8 0.0 2.5e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain PAP_assoc PF03828.19 KXS14822.1 - 2e-14 53.6 0.0 4.7e-14 52.3 0.0 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 KXS14822.1 - 8.1e-06 26.0 0.0 2.7e-05 24.4 0.0 1.9 1 0 0 1 1 1 1 Nucleotidyltransferase domain Nrap_D2 PF17403.2 KXS14822.1 - 0.13 12.0 0.0 0.45 10.3 0.0 1.8 2 0 0 2 2 2 0 Nrap protein PAP/OAS-like domain ECH_1 PF00378.20 KXS14823.1 - 7.3e-40 136.9 0.0 9.6e-40 136.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXS14823.1 - 8e-19 68.3 0.0 9.6e-19 68.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase SET PF00856.28 KXS14824.1 - 8.7e-12 45.7 0.2 2.1e-10 41.3 0.2 2.3 1 1 0 1 1 1 1 SET domain Pre-SET PF05033.16 KXS14824.1 - 2.8e-10 40.8 3.1 2.8e-10 40.8 3.1 1.9 2 0 0 2 2 2 1 Pre-SET motif p450 PF00067.22 KXS14825.1 - 0.11 11.2 1.1 4.6 5.9 0.0 2.1 1 1 1 2 2 2 0 Cytochrome P450 PNP_UDP_1 PF01048.20 KXS14826.1 - 2.6e-39 134.9 0.3 3.3e-39 134.5 0.3 1.2 1 0 0 1 1 1 1 Phosphorylase superfamily ABM PF03992.16 KXS14828.1 - 0.0017 18.4 0.0 0.0025 17.9 0.0 1.3 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase DUF4188 PF13826.6 KXS14828.1 - 0.0026 18.1 0.1 0.0029 17.9 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4188) DUF3291 PF11695.8 KXS14828.1 - 0.004 16.9 0.1 0.0075 16.0 0.1 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF3291) Glyco_transf_34 PF05637.12 KXS14830.1 - 2.3e-15 57.0 0.0 5.9e-09 36.0 0.0 2.1 2 0 0 2 2 2 2 galactosyl transferase GMA12/MNN10 family Nucleotid_trans PF03407.16 KXS14830.1 - 2.6e-05 24.3 0.0 3.6e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Oxidored_q6 PF01058.22 KXS14831.1 - 4e-16 59.0 0.0 5.6e-16 58.6 0.0 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Carn_acyltransf PF00755.20 KXS14832.1 - 1.5e-163 545.6 0.0 1.7e-163 545.4 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase QslA_E PF18226.1 KXS14832.1 - 0.098 12.6 2.0 0.77 9.7 0.1 2.7 3 0 0 3 3 3 0 LasR-specific antiactivator QslA chain E PA_decarbox PF05870.11 KXS14832.1 - 0.17 11.5 0.0 0.51 9.9 0.0 1.8 1 0 0 1 1 1 0 Phenolic acid decarboxylase (PAD) ubiquitin PF00240.23 KXS14834.1 - 0.065 13.0 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin family DUF3839 PF12943.7 KXS14834.1 - 0.084 12.3 0.0 0.096 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3839) TcpQ PF10671.9 KXS14837.1 - 0.06 13.5 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Toxin co-regulated pilus biosynthesis protein Q Glyco_transf_17 PF04724.13 KXS14839.1 - 1.3e-128 429.0 0.0 1.4e-128 428.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 17 Aldedh PF00171.22 KXS14841.1 - 1.3e-186 620.6 0.9 1.5e-186 620.4 0.9 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KXS14841.1 - 1.3e-05 24.5 0.0 2.1e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.11 KXS14841.1 - 0.00029 20.3 0.0 0.0023 17.4 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) Pkinase PF00069.25 KXS14842.1 - 1.3e-32 113.2 0.0 1.5e-32 113.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS14842.1 - 6.6e-13 48.5 0.0 8e-13 48.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXS14842.1 - 0.00093 18.6 0.0 0.0015 17.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KXS14842.1 - 0.02 13.7 0.0 0.022 13.5 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 KXS14842.1 - 0.1 11.5 0.0 0.13 11.2 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 KXS14842.1 - 0.19 11.0 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Acyl_transf_1 PF00698.21 KXS14844.1 - 2.1e-15 57.1 0.1 2.5e-15 56.8 0.1 1.1 1 0 0 1 1 1 1 Acyl transferase domain tRNA-synt_1b PF00579.25 KXS14845.1 - 9.9e-21 74.3 0.0 3.5e-11 43.0 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (W and Y) Pro_isomerase PF00160.21 KXS14846.1 - 3e-39 134.8 0.0 5.2e-39 134.1 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Rhodanese PF00581.20 KXS14847.1 - 0.001 19.6 0.0 0.0043 17.6 0.0 1.8 1 1 0 1 1 1 1 Rhodanese-like domain F_actin_bind PF08919.10 KXS14848.1 - 0.024 14.7 0.0 0.059 13.5 0.0 1.6 1 0 0 1 1 1 0 F-actin binding RIIa PF02197.17 KXS14849.1 - 0.0028 17.3 0.0 0.005 16.5 0.0 1.3 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit PAT1 PF09770.9 KXS14850.1 - 9.4e-91 305.4 23.9 5.5e-82 276.4 0.0 4.3 3 1 2 5 5 5 3 Topoisomerase II-associated protein PAT1 DUF3336 PF11815.8 KXS14851.1 - 2.4e-14 53.2 0.0 3.1e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) DUF1819 PF08849.11 KXS14851.1 - 0.09 12.6 0.0 1.7 8.4 0.1 2.0 2 0 0 2 2 2 0 Putative inner membrane protein (DUF1819) FA_hydroxylase PF04116.13 KXS14856.1 - 1.4e-23 83.7 8.0 3e-23 82.6 8.0 1.6 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily Herpes_HEPA PF03324.14 KXS14856.1 - 0.098 13.1 0.0 0.32 11.5 0.0 1.8 1 0 0 1 1 1 0 Herpesvirus DNA helicase/primase complex associated protein DUF1286 PF06939.11 KXS14856.1 - 0.28 11.4 3.6 6.1 7.2 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1286) ubiquitin PF00240.23 KXS14857.1 - 4.6e-13 48.7 0.0 7.6e-13 48.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 KXS14857.1 - 1.6e-08 34.3 0.1 3.7e-08 33.1 0.1 1.7 1 0 0 1 1 1 1 UBA/TS-N domain Rad60-SLD PF11976.8 KXS14857.1 - 4.8e-06 26.3 0.0 9.6e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 KXS14857.1 - 8e-06 26.4 0.0 1.4e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 KXS14857.1 - 3e-05 24.1 0.0 5.1e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like YukD PF08817.10 KXS14857.1 - 0.041 14.6 0.1 0.091 13.5 0.1 1.6 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD Ubiquitin_4 PF18036.1 KXS14857.1 - 0.28 11.2 0.2 1.8 8.7 0.2 2.0 1 1 0 1 1 1 0 Ubiquitin-like domain STI1 PF17830.1 KXS14857.1 - 0.29 11.1 18.9 1.6 8.7 8.9 2.6 2 0 0 2 2 2 0 STI1 domain DSBA PF01323.20 KXS14859.1 - 1.4e-19 70.6 0.0 1.7e-19 70.4 0.0 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain SinI PF08671.10 KXS14859.1 - 0.036 13.9 0.0 0.071 12.9 0.0 1.5 1 0 0 1 1 1 0 Anti-repressor SinI Polysacc_deac_1 PF01522.21 KXS14860.1 - 1.8e-22 79.5 0.0 3.1e-22 78.8 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 KXS14860.1 - 0.024 14.3 0.0 0.044 13.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) Glyco_hydro_79C PF16862.5 KXS14860.1 - 0.52 11.2 3.9 2.2 9.2 0.7 2.8 2 0 0 2 2 2 0 Glycosyl hydrolase family 79 C-terminal beta domain Polysacc_deac_1 PF01522.21 KXS14861.1 - 0.00032 20.6 0.0 0.00049 20.0 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase ATP_bind_2 PF03668.15 KXS14862.1 - 0.16 11.3 0.0 1.1 8.5 0.0 1.9 2 0 0 2 2 2 0 P-loop ATPase protein family Rieske PF00355.26 KXS14863.1 - 3.6e-10 39.7 0.0 5.9e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 KXS14863.1 - 0.0024 17.8 0.0 0.0037 17.2 0.0 1.3 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Metallophos PF00149.28 KXS14864.1 - 2e-12 48.0 0.0 2.7e-12 47.6 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF3578 PF12102.8 KXS14864.1 - 0.0024 17.5 0.0 0.0037 16.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3578) Rieske PF00355.26 KXS14865.1 - 0.018 14.9 0.0 0.048 13.6 0.0 1.7 1 0 0 1 1 1 0 Rieske [2Fe-2S] domain Ank_3 PF13606.6 KXS14866.1 - 1.3e-05 25.1 1.4 2.1 9.2 0.1 4.4 5 0 0 5 5 5 2 Ankyrin repeat Ank_2 PF12796.7 KXS14866.1 - 0.00046 20.7 1.2 0.0077 16.8 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KXS14866.1 - 0.75 10.3 6.6 9.2 6.9 0.2 3.4 4 0 0 4 4 4 0 Ankyrin repeat Ribosomal_L12 PF00542.19 KXS14868.1 - 1.7e-22 79.5 12.2 2.2e-22 79.2 9.1 2.1 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 KXS14868.1 - 4.4e-09 35.9 22.8 8.8e-08 31.7 19.5 3.4 2 1 0 2 2 2 1 Ribosomal protein L7/L12 dimerisation domain Ribosomal_60s PF00428.19 KXS14868.1 - 0.55 10.8 15.2 0.052 14.2 8.3 2.3 1 1 2 3 3 3 0 60s Acidic ribosomal protein PK PF00224.21 KXS14870.1 - 5.8e-139 462.8 1.6 7e-139 462.5 1.6 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 KXS14870.1 - 4.6e-30 104.3 0.6 1e-29 103.2 0.6 1.6 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 KXS14870.1 - 0.004 16.3 0.5 0.011 14.9 0.3 1.9 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.25 KXS14870.1 - 0.031 13.3 0.2 0.13 11.2 0.0 2.0 3 0 0 3 3 3 0 IMP dehydrogenase / GMP reductase domain YajC PF02699.15 KXS14870.1 - 0.14 12.1 2.4 11 6.0 0.5 2.6 2 0 0 2 2 2 0 Preprotein translocase subunit HMGL-like PF00682.19 KXS14874.1 - 4.3e-75 252.7 0.0 6e-75 252.2 0.0 1.2 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 KXS14874.1 - 5.2e-33 113.8 0.1 9.6e-33 112.9 0.1 1.5 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain Sigma_reg_N PF13800.6 KXS14874.1 - 0.19 12.1 0.0 0.37 11.1 0.0 1.4 1 0 0 1 1 1 0 Sigma factor regulator N-terminal Pyr_redox_2 PF07992.14 KXS14875.1 - 1.1e-10 41.3 0.0 1.2e-08 34.5 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXS14875.1 - 5.6e-09 35.7 0.1 2e-07 30.5 0.0 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KXS14875.1 - 1.8e-08 33.3 0.0 3.2e-07 29.2 0.0 2.2 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KXS14875.1 - 3.2e-07 29.8 0.0 1.7e-06 27.4 0.0 2.0 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KXS14875.1 - 5e-06 26.7 0.0 4.2e-05 23.7 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KXS14875.1 - 0.00069 18.9 0.0 0.21 10.8 0.0 2.3 2 0 0 2 2 2 2 Thi4 family NAD_binding_9 PF13454.6 KXS14875.1 - 0.0022 18.0 0.0 16 5.4 0.0 3.6 3 1 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 KXS14875.1 - 0.047 14.3 0.0 9.2 6.9 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXS14875.1 - 0.13 11.0 0.0 37 2.9 0.0 3.1 3 0 0 3 3 3 0 HI0933-like protein F-box PF00646.33 KXS14877.1 - 5.7e-07 29.3 0.4 1.8e-06 27.7 0.4 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KXS14877.1 - 3.2e-06 26.9 1.2 3.2e-06 26.9 1.2 2.1 2 0 0 2 2 2 1 F-box-like RWP-RK PF02042.15 KXS14877.1 - 1.2 9.2 3.9 1.2 9.1 0.0 2.8 3 0 0 3 3 3 0 RWP-RK domain F-box-like PF12937.7 KXS14878.1 - 0.00061 19.6 0.0 0.0015 18.4 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXS14878.1 - 0.0019 18.0 0.1 0.004 17.0 0.1 1.6 1 0 0 1 1 1 1 F-box domain DUF3604 PF12228.8 KXS14878.1 - 0.0038 15.7 0.1 0.0054 15.2 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3604) WD40 PF00400.32 KXS14878.1 - 0.17 12.8 3.4 2 9.4 0.0 4.1 3 1 0 3 3 3 0 WD domain, G-beta repeat Rep_fac_C PF08542.11 KXS14879.1 - 2.2e-15 56.8 0.0 4e-15 56.0 0.0 1.5 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.29 KXS14879.1 - 6.8e-15 55.7 0.0 1.4e-14 54.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 KXS14879.1 - 7.4e-13 48.6 0.0 2.8e-12 46.7 0.0 1.8 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.15 KXS14879.1 - 4.1e-06 26.9 0.0 7.5e-06 26.0 0.0 1.4 2 0 0 2 2 1 1 Rad17 P-loop domain RuvB_N PF05496.12 KXS14879.1 - 8.8e-05 22.3 0.0 0.00026 20.8 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain DUF2075 PF09848.9 KXS14879.1 - 9.4e-05 21.8 0.0 0.00013 21.3 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_14 PF13173.6 KXS14879.1 - 0.00012 22.2 0.0 0.012 15.7 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 KXS14879.1 - 0.00027 21.3 0.3 0.011 16.1 0.0 2.5 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 KXS14879.1 - 0.00045 20.5 0.0 0.0024 18.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KXS14879.1 - 0.00051 19.9 0.0 0.00094 19.0 0.0 1.5 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 KXS14879.1 - 0.00054 19.2 0.0 0.00077 18.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_24 PF13479.6 KXS14879.1 - 0.00055 19.7 0.0 0.001 18.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KXS14879.1 - 0.00092 19.0 0.0 0.0016 18.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_assoc_2 PF16193.5 KXS14879.1 - 0.00097 19.4 0.0 0.0029 17.9 0.0 1.8 1 0 0 1 1 1 1 AAA C-terminal domain AAA_19 PF13245.6 KXS14879.1 - 0.0015 18.8 0.0 0.005 17.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KXS14879.1 - 0.0019 17.6 0.0 0.029 13.7 0.0 2.4 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 KXS14879.1 - 0.0062 16.1 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_5 PF07728.14 KXS14879.1 - 0.0078 16.2 0.0 0.029 14.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) ResIII PF04851.15 KXS14879.1 - 0.021 14.8 0.0 0.055 13.5 0.0 1.7 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit MCM PF00493.23 KXS14879.1 - 0.023 13.8 0.0 3.7 6.6 0.0 2.2 2 0 0 2 2 2 0 MCM P-loop domain DEAD PF00270.29 KXS14879.1 - 0.072 12.9 0.1 0.44 10.3 0.0 2.1 1 1 0 2 2 2 0 DEAD/DEAH box helicase AAA_3 PF07726.11 KXS14879.1 - 0.075 12.9 0.0 0.77 9.6 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MeaB PF03308.16 KXS14879.1 - 0.076 12.0 0.0 5.8 5.8 0.0 2.2 1 1 1 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB SIS PF01380.22 KXS14880.1 - 1e-50 170.9 0.1 3.3e-30 104.6 0.1 3.2 3 0 0 3 3 3 2 SIS domain GATase_6 PF13522.6 KXS14880.1 - 7.3e-16 58.6 0.0 1.5e-15 57.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 KXS14880.1 - 3.2e-10 40.0 0.0 6.6e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 KXS14880.1 - 2e-06 26.9 0.1 4.3e-06 25.8 0.1 1.5 1 0 0 1 1 1 1 Glutamine amidotransferases class-II MucBP_2 PF17965.1 KXS14880.1 - 0.035 14.7 0.2 0.086 13.4 0.2 1.7 1 0 0 1 1 1 0 Mucin binding domain Hydrolase PF00702.26 KXS14880.1 - 0.059 13.6 0.0 0.27 11.5 0.0 2.1 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase SIS_2 PF13580.6 KXS14880.1 - 0.12 12.4 0.0 0.47 10.5 0.0 1.9 1 1 1 2 2 2 0 SIS domain NUDIX PF00293.28 KXS14881.1 - 8.3e-08 32.3 0.5 7.5e-05 22.8 0.5 3.2 1 1 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 KXS14881.1 - 0.03 14.3 0.1 0.25 11.3 0.0 2.2 2 0 0 2 2 2 0 NUDIX domain eIF3_subunit PF08597.10 KXS14883.1 - 7.5e-48 163.6 18.5 8.5e-48 163.4 18.5 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit PAP_RNA-bind PF04926.15 KXS14883.1 - 0.065 12.9 0.1 0.17 11.5 0.0 1.7 2 0 0 2 2 2 0 Poly(A) polymerase predicted RNA binding domain RAP1 PF07218.11 KXS14883.1 - 0.99 7.6 3.8 1.8 6.7 3.8 1.4 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) FancD2 PF14631.6 KXS14883.1 - 1.1 6.6 4.9 0.38 8.1 0.0 2.0 2 0 0 2 2 2 0 Fanconi anaemia protein FancD2 nuclease Nucleo_P87 PF07267.11 KXS14883.1 - 8.6 5.1 8.7 12 4.6 8.7 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Glyco_hydro_18 PF00704.28 KXS14884.1 - 2.3e-14 53.9 0.3 2.5e-13 50.4 0.3 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 DUF5482 PF17579.2 KXS14884.1 - 0.022 14.6 0.0 0.044 13.7 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5482) Sigma_reg_N PF13800.6 KXS14884.1 - 0.2 12.0 1.4 0.41 11.0 0.6 1.8 2 0 0 2 2 2 0 Sigma factor regulator N-terminal LRR_6 PF13516.6 KXS14886.1 - 2.1e-35 117.8 32.6 6.5e-05 22.7 0.0 10.2 10 0 0 10 10 10 7 Leucine Rich repeat Sel1 PF08238.12 KXS14886.1 - 5.8e-09 36.3 6.1 2.6e-06 27.9 0.3 3.5 4 0 0 4 4 4 2 Sel1 repeat LRR_4 PF12799.7 KXS14886.1 - 3.2e-07 30.6 19.7 0.36 11.3 0.4 5.8 4 2 2 6 6 6 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KXS14886.1 - 6.9e-07 29.0 5.7 6.1 7.8 0.0 8.1 9 0 0 9 9 9 1 Leucine Rich Repeat LRR_8 PF13855.6 KXS14886.1 - 2.5e-05 23.9 21.2 0.037 13.8 1.3 6.8 3 3 2 5 5 5 4 Leucine rich repeat Pkinase PF00069.25 KXS14887.1 - 3.1e-19 69.4 0.0 3.4e-19 69.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS14887.1 - 6e-19 68.3 0.0 7.2e-19 68.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 KXS14887.1 - 0.0011 18.6 0.0 0.0014 18.2 0.0 1.1 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 KXS14887.1 - 0.002 18.1 0.0 0.032 14.1 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 KXS14887.1 - 0.077 12.5 0.0 0.1 12.1 0.0 1.1 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Pkinase_fungal PF17667.1 KXS14887.1 - 0.12 11.2 0.0 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 KXS14887.1 - 0.18 11.1 0.0 0.24 10.7 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KXS14888.1 - 0.041 13.2 0.0 0.056 12.8 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain Pkinase_Tyr PF07714.17 KXS14888.1 - 0.047 13.0 0.0 0.066 12.5 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase FTA2 PF13095.6 KXS14888.1 - 0.19 11.3 0.0 0.27 10.8 0.0 1.1 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 DUF3712 PF12505.8 KXS14889.1 - 6.8e-09 36.1 10.0 3.8e-05 24.0 0.1 4.4 6 0 0 6 6 6 2 Protein of unknown function (DUF3712) LEA_2 PF03168.13 KXS14889.1 - 3.9e-05 24.1 0.1 0.023 15.2 0.0 3.8 4 0 0 4 4 4 1 Late embryogenesis abundant protein PqqA PF08042.11 KXS14889.1 - 0.079 13.0 0.9 0.22 11.6 0.0 2.2 2 0 0 2 2 2 0 PqqA family NADH_dehy_S2_C PF06444.11 KXS14889.1 - 0.087 13.4 1.8 0.37 11.3 1.8 2.1 1 0 0 1 1 1 0 NADH dehydrogenase subunit 2 C-terminus CLAMP PF14769.6 KXS14890.1 - 5.5e-17 62.0 0.0 1.7e-16 60.5 0.0 1.9 1 1 0 1 1 1 1 Flagellar C1a complex subunit C1a-32 WD40 PF00400.32 KXS14891.1 - 4e-26 90.8 8.3 2.7e-05 24.8 0.8 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat F-box-like PF12937.7 KXS14891.1 - 2.2e-06 27.5 0.2 3.9e-06 26.7 0.2 1.4 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 KXS14891.1 - 5e-05 23.5 0.1 2.4 8.5 0.1 4.0 4 0 0 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 KXS14891.1 - 0.11 13.1 1.2 4.9 7.8 0.0 4.1 4 0 0 4 4 4 0 PQQ-like domain BUD22 PF09073.10 KXS14892.1 - 0.07 12.5 13.1 0.079 12.3 13.1 1.2 1 0 0 1 1 1 0 BUD22 PRP38_assoc PF12871.7 KXS14892.1 - 1.1 9.9 19.1 2.1 9.0 11.0 2.4 2 0 0 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term DUF2236 PF09995.9 KXS14893.1 - 4.9e-27 95.6 0.0 3.2e-26 93.0 0.0 2.0 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2236) Pkinase PF00069.25 KXS14895.1 - 5e-28 98.2 0.0 5.5e-28 98.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS14895.1 - 1.5e-26 93.3 0.0 1.6e-26 93.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXS14895.1 - 9.9e-10 37.7 0.0 1.1e-09 37.6 0.0 1.0 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KXS14895.1 - 0.00049 19.5 0.0 0.0006 19.2 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXS14895.1 - 0.0014 18.6 0.0 0.0014 18.6 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 KXS14895.1 - 0.15 11.7 0.0 0.18 11.4 0.0 1.1 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 KXS14895.1 - 0.16 11.5 0.0 0.21 11.2 0.0 1.1 1 0 0 1 1 1 0 RIO1 family Sel1 PF08238.12 KXS14896.1 - 1.1e-56 188.0 26.3 1.3e-10 41.6 0.3 7.9 8 0 0 8 8 8 6 Sel1 repeat TPR_16 PF13432.6 KXS14896.1 - 1.8e-08 34.9 17.3 0.024 15.3 1.0 4.8 1 1 4 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 KXS14896.1 - 4.9e-05 22.9 27.1 0.0039 16.8 1.3 6.7 6 2 0 6 6 6 3 TPR repeat TPR_6 PF13174.6 KXS14896.1 - 0.00022 21.7 5.5 18 6.2 0.1 6.1 5 1 1 6 6 6 1 Tetratricopeptide repeat KID PF02524.14 KXS14896.1 - 0.052 13.6 6.5 42 4.9 0.1 4.4 4 0 0 4 4 4 0 KID repeat DUF2735 PF10931.8 KXS14896.1 - 0.4 11.4 3.6 27 5.6 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2735) TPR_8 PF13181.6 KXS14896.1 - 1.1 9.6 19.6 1.1 9.7 0.3 6.8 7 2 1 8 8 8 0 Tetratricopeptide repeat TPR_1 PF00515.28 KXS14896.1 - 3.9 7.5 34.9 4.9 7.1 0.2 9.8 11 0 0 11 11 11 0 Tetratricopeptide repeat Sld5 PF05916.11 KXS14897.1 - 2.8e-21 76.0 0.2 4.1e-21 75.5 0.2 1.2 1 0 0 1 1 1 1 GINS complex protein RRM_1 PF00076.22 KXS14898.1 - 1.5e-12 47.2 0.1 2.7e-12 46.3 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.23 KXS14898.1 - 0.00015 21.7 5.2 0.00028 20.8 5.2 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 KXS14898.1 - 0.0021 18.0 0.3 0.0043 17.0 0.3 1.5 1 0 0 1 1 1 1 Zinc knuckle RRM_3 PF08777.11 KXS14898.1 - 0.0043 17.1 0.1 0.009 16.0 0.0 1.5 2 0 0 2 2 2 1 RNA binding motif EF-hand_8 PF13833.6 KXS14900.1 - 1.8e-08 34.1 0.5 2.4e-05 24.1 0.1 2.4 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 KXS14900.1 - 0.0014 18.1 0.5 0.0027 17.1 0.1 1.8 2 0 0 2 2 2 1 EF hand WASH-7_N PF14745.6 KXS14900.1 - 0.0035 15.9 0.0 0.0037 15.8 0.0 1.0 1 0 0 1 1 1 1 WASH complex subunit 7, N-terminal EF-hand_7 PF13499.6 KXS14900.1 - 0.0042 17.5 0.1 0.019 15.4 0.0 2.0 2 1 0 2 2 2 1 EF-hand domain pair EFhand_Ca_insen PF08726.10 KXS14900.1 - 0.0066 16.5 0.3 0.24 11.5 0.3 2.8 2 1 0 2 2 2 1 Ca2+ insensitive EF hand EF-hand_6 PF13405.6 KXS14900.1 - 0.022 14.7 0.2 0.13 12.3 0.0 2.2 2 1 0 2 2 2 0 EF-hand domain EF-hand_9 PF14658.6 KXS14900.1 - 0.03 14.6 0.0 0.062 13.6 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain AAA_25 PF13481.6 KXS14900.1 - 0.06 12.9 0.2 0.12 12.0 0.1 1.4 1 1 0 1 1 1 0 AAA domain Drf_FH3 PF06367.16 KXS14901.1 - 0.0057 16.3 11.2 0.012 15.3 8.2 2.5 2 1 1 3 3 3 1 Diaphanous FH3 Domain DUF2383 PF09537.10 KXS14901.1 - 0.064 13.6 7.5 0.15 12.4 5.5 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF2383) GAS PF13851.6 KXS14901.1 - 0.079 12.3 40.5 0.042 13.2 13.4 3.2 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding Mac PF12464.8 KXS14901.1 - 0.4 11.0 1.8 1.2 9.4 1.8 1.8 1 0 0 1 1 1 0 Maltose acetyltransferase FPP PF05911.11 KXS14901.1 - 1.7 6.7 33.3 0.41 8.8 19.1 2.3 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil DUF1664 PF07889.12 KXS14901.1 - 2.4 8.2 21.7 8.8 6.4 4.2 3.8 2 1 0 3 3 3 0 Protein of unknown function (DUF1664) DUF948 PF06103.11 KXS14901.1 - 2.7 8.3 11.9 2.1 8.7 1.7 3.2 2 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) AAA_13 PF13166.6 KXS14901.1 - 2.7 6.5 25.4 0.23 10.0 20.0 1.7 2 0 0 2 2 2 0 AAA domain ATG16 PF08614.11 KXS14901.1 - 2.9 8.1 50.5 0.024 14.9 22.7 4.3 3 1 1 4 4 4 0 Autophagy protein 16 (ATG16) Mto2_bdg PF12808.7 KXS14901.1 - 6.2 7.2 16.2 0.58 10.5 2.0 3.6 3 0 0 3 3 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region MCC-bdg_PDZ PF10506.9 KXS14901.1 - 8.2 6.5 12.5 4.9 7.2 5.6 2.8 2 0 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome WD40 PF00400.32 KXS14902.1 - 3.1e-49 163.9 13.9 5.1e-09 36.6 0.0 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 KXS14902.1 - 1.1e-35 122.7 0.0 1.9e-35 121.9 0.0 1.3 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain ANAPC4_WD40 PF12894.7 KXS14902.1 - 4.5e-15 55.7 0.1 0.021 15.1 0.0 5.4 3 1 2 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KXS14902.1 - 1.9e-06 27.4 0.0 0.19 11.0 0.0 4.3 3 1 2 5 5 5 2 WD40-like domain Ge1_WD40 PF16529.5 KXS14902.1 - 5.6e-05 22.3 0.0 0.76 8.7 0.0 3.7 2 2 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 KXS14902.1 - 7.3e-05 21.7 0.0 0.0096 14.7 0.0 3.0 3 0 0 3 3 3 1 Nup133 N terminal like Nup160 PF11715.8 KXS14902.1 - 0.00016 20.4 0.7 2.3 6.8 0.2 3.6 3 1 1 4 4 4 2 Nucleoporin Nup120/160 eIF2A PF08662.11 KXS14902.1 - 0.00039 20.3 0.0 0.0028 17.6 0.0 2.2 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 KXS14902.1 - 0.0029 17.5 0.0 1.9 8.5 0.0 3.2 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat RAB3GAP2_N PF14655.6 KXS14902.1 - 0.21 10.8 0.1 4.1 6.6 0.0 2.4 2 1 1 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus RabGAP-TBC PF00566.18 KXS14903.1 - 1.7e-45 155.3 0.0 3.4e-45 154.3 0.0 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain GRAM PF02893.20 KXS14903.1 - 1.3e-24 86.3 0.2 3e-16 59.3 0.1 2.5 2 0 0 2 2 2 2 GRAM domain PHD PF00628.29 KXS14904.1 - 6.4e-07 29.2 2.1 6.4e-07 29.2 2.1 1.9 2 0 0 2 2 2 1 PHD-finger C1_1 PF00130.22 KXS14904.1 - 0.0078 16.1 4.1 0.015 15.2 4.1 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Avl9 PF09794.9 KXS14905.1 - 3.2e-51 174.2 0.0 1.7e-50 171.9 0.0 1.9 1 1 0 1 1 1 1 Transport protein Avl9 SPA PF08616.10 KXS14905.1 - 0.0068 16.4 0.0 0.033 14.1 0.0 2.1 2 0 0 2 2 2 1 Stabilization of polarity axis PRELI PF04707.14 KXS14906.1 - 1.2e-33 116.2 0.3 8.6e-33 113.4 0.3 2.0 1 1 0 1 1 1 1 PRELI-like family DUF1218 PF06749.12 KXS14907.1 - 0.13 12.8 1.3 0.23 12.0 0.1 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1218) UPF0242 PF06785.11 KXS14907.1 - 0.2 11.7 0.0 0.39 10.8 0.0 1.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus T_cell_tran_alt PF15128.6 KXS14907.1 - 0.24 11.2 1.0 29 4.6 1.3 2.2 2 0 0 2 2 2 0 T-cell leukemia translocation-altered DUF2956 PF11169.8 KXS14907.1 - 0.51 10.5 3.1 0.55 10.4 0.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) Usp PF00582.26 KXS14908.1 - 3e-14 53.7 0.1 5.1e-14 53.0 0.1 1.3 1 0 0 1 1 1 1 Universal stress protein family SOGA PF11365.8 KXS14909.1 - 0.021 16.0 2.0 0.021 16.0 2.0 6.9 5 3 2 7 7 7 0 Protein SOGA BRCT PF00533.26 KXS14909.1 - 0.11 12.9 0.0 0.95 9.9 0.0 2.5 1 1 1 2 2 2 0 BRCA1 C Terminus (BRCT) domain Fez1 PF06818.15 KXS14909.1 - 0.49 10.8 62.1 0.075 13.5 16.0 4.2 3 1 0 3 3 3 0 Fez1 IL2 PF00715.17 KXS14909.1 - 7.7 6.5 7.0 22 4.9 0.8 3.9 4 0 0 4 4 4 0 Interleukin 2 LLC1 PF14945.6 KXS14911.1 - 9.2e-10 39.1 0.1 1.8e-06 28.5 0.0 2.2 2 0 0 2 2 2 2 Normal lung function maintenance, Low in Lung Cancer 1 protein FAM183 PF14886.6 KXS14911.1 - 0.0011 19.7 0.1 0.0025 18.5 0.1 1.6 1 1 0 1 1 1 1 FAM183A and FAM183B related ARD PF03079.14 KXS14913.1 - 2.5e-27 96.0 0.0 2.9e-27 95.8 0.0 1.1 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 KXS14913.1 - 1.7e-06 27.6 0.1 3.2e-06 26.7 0.1 1.4 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 KXS14913.1 - 0.0014 18.5 0.3 0.0025 17.7 0.0 1.5 2 0 0 2 2 2 1 AraC-like ligand binding domain p450 PF00067.22 KXS14914.1 - 3.4e-14 52.4 0.0 4.1e-14 52.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FSH1 PF03959.13 KXS14915.1 - 6.6e-33 114.2 0.0 1.9e-32 112.7 0.0 1.7 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.20 KXS14915.1 - 0.0099 15.5 0.0 0.16 11.6 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF2048 PF09752.9 KXS14915.1 - 0.011 14.9 0.0 0.2 10.7 0.0 2.1 2 0 0 2 2 2 0 Abhydrolase domain containing 18 PHY PF00360.20 KXS14916.1 - 7.4e-23 80.8 0.1 1.4e-22 79.9 0.1 1.4 1 0 0 1 1 1 1 Phytochrome region HATPase_c PF02518.26 KXS14916.1 - 5.3e-22 78.4 0.0 1.4e-21 77.1 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KXS14916.1 - 3.4e-17 62.6 0.0 1.2e-10 41.6 0.1 2.6 2 0 0 2 2 2 2 Response regulator receiver domain HisKA PF00512.25 KXS14916.1 - 1.1e-13 51.0 0.5 3.7e-13 49.3 0.5 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF PF01590.26 KXS14916.1 - 2.8e-13 50.6 0.0 8.5e-13 49.1 0.0 1.9 1 0 0 1 1 1 1 GAF domain PAS_2 PF08446.11 KXS14916.1 - 3.5e-07 30.9 0.0 1.2e-06 29.1 0.0 2.0 1 0 0 1 1 1 1 PAS fold HATPase_c_5 PF14501.6 KXS14916.1 - 0.18 11.7 0.0 0.48 10.4 0.0 1.7 1 0 0 1 1 1 0 GHKL domain GP40 PF11025.8 KXS14917.1 - 0.044 13.5 0.4 0.11 12.3 0.0 1.8 2 1 0 2 2 2 0 Glycoprotein GP40 of Cryptosporidium Methyltransf_16 PF10294.9 KXS14918.1 - 7.3e-16 58.4 0.0 9.6e-16 58.0 0.0 1.0 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 KXS14918.1 - 0.00018 21.1 0.0 0.00023 20.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 KXS14918.1 - 0.033 14.9 0.0 0.054 14.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 KXS14918.1 - 0.068 13.9 0.0 0.11 13.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 KXS14918.1 - 0.14 11.9 0.0 0.19 11.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain PPR_2 PF13041.6 KXS14919.1 - 5.1e-32 109.8 0.0 2.6e-08 33.9 0.0 7.9 6 1 3 9 9 9 6 PPR repeat family PPR_3 PF13812.6 KXS14919.1 - 3.3e-28 97.6 0.0 3.8e-09 36.5 0.0 5.4 6 0 0 6 6 6 3 Pentatricopeptide repeat domain PPR PF01535.20 KXS14919.1 - 8.3e-25 85.3 2.6 1.8e-05 24.6 0.1 8.3 8 0 0 8 8 8 4 PPR repeat PPR_1 PF12854.7 KXS14919.1 - 5.9e-14 51.5 0.1 0.073 12.8 0.0 7.0 8 0 0 8 8 8 4 PPR repeat PPR_long PF17177.4 KXS14919.1 - 5.7e-11 42.2 0.0 8.8e-07 28.5 0.0 3.3 3 0 0 3 3 3 2 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 KXS14919.1 - 3.2e-10 39.9 12.3 0.17 12.8 1.3 7.5 6 2 1 7 7 7 3 Tetratricopeptide repeat TPR_4 PF07721.14 KXS14919.1 - 0.00065 20.1 6.6 0.2 12.4 0.0 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 KXS14919.1 - 0.011 16.3 0.2 3.5 8.2 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat SPOB_a PF14689.6 KXS14919.1 - 0.052 13.3 0.1 12 5.7 0.0 2.8 3 0 0 3 3 3 0 Sensor_kinase_SpoOB-type, alpha-helical domain Wzy_C_2 PF11846.8 KXS14919.1 - 0.053 13.4 0.0 5.9 6.8 0.0 3.0 3 0 0 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal SH3_9 PF14604.6 KXS14921.1 - 0.00033 20.4 0.0 0.00068 19.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXS14921.1 - 0.015 14.9 0.0 0.025 14.2 0.0 1.4 1 0 0 1 1 1 0 SH3 domain Lactamase_B PF00753.27 KXS14923.1 - 9e-09 35.6 0.3 6e-07 29.7 0.1 2.6 2 1 1 3 3 3 2 Metallo-beta-lactamase superfamily Arylesterase PF01731.20 KXS14924.1 - 1.3e-08 34.9 0.1 0.0036 17.5 0.1 3.0 2 1 1 3 3 3 2 Arylesterase SGL PF08450.12 KXS14924.1 - 6.7e-05 22.6 0.0 0.00022 20.9 0.0 1.8 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region LapA_dom PF06305.11 KXS14925.1 - 0.01 15.7 0.2 0.015 15.1 0.2 1.2 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain PK PF00224.21 KXS14926.1 - 3.1e-109 365.1 1.4 8.5e-61 205.8 0.6 2.1 2 0 0 2 2 2 2 Pyruvate kinase, barrel domain PK_C PF02887.16 KXS14926.1 - 3.5e-17 62.7 1.6 6e-17 62.0 0.3 2.1 3 0 0 3 3 3 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 KXS14926.1 - 0.0014 17.8 0.1 0.0026 17.0 0.1 1.4 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family Zn_clus PF00172.18 KXS14927.1 - 3.4e-06 27.1 10.6 6.9e-06 26.1 10.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXS14927.1 - 0.0037 16.3 0.0 0.0068 15.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain AMP-binding PF00501.28 KXS14928.1 - 1.7e-88 297.0 0.1 2e-88 296.8 0.1 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXS14928.1 - 1e-21 77.7 0.2 2.1e-21 76.7 0.2 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain HSP20 PF00011.21 KXS14929.1 - 4.9e-26 90.8 2.2 6.4e-26 90.5 2.2 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KXS14929.1 - 1.8e-11 43.4 0.0 2.8e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 HSP20-like domain found in ArsA PIH1_CS PF18201.1 KXS14929.1 - 0.057 13.8 0.0 0.12 12.8 0.0 1.5 1 1 0 1 1 1 0 PIH1 CS-like domain Frataxin_Cyay PF01491.16 KXS14929.1 - 0.12 12.5 0.1 0.53 10.4 0.0 1.8 1 1 1 2 2 2 0 Frataxin-like domain DUF1295 PF06966.12 KXS14930.1 - 1e-44 152.8 0.4 1.5e-44 152.3 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.13 KXS14930.1 - 0.0012 19.3 0.3 1.1 9.7 0.0 2.6 2 0 0 2 2 2 2 Phospholipid methyltransferase ICMT PF04140.14 KXS14930.1 - 0.13 12.7 0.0 0.35 11.3 0.0 1.6 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Steroid_dh PF02544.16 KXS14930.1 - 0.18 11.8 1.5 0.44 10.5 1.6 1.8 1 1 0 1 1 1 0 3-oxo-5-alpha-steroid 4-dehydrogenase rRNA_processing PF08524.11 KXS14931.1 - 2.8e-14 53.4 5.6 2.8e-14 53.4 5.6 3.1 3 0 0 3 3 3 2 rRNA processing DNA_pol_phi PF04931.13 KXS14931.1 - 0.89 7.6 6.4 1.1 7.2 6.4 1.4 1 0 0 1 1 1 0 DNA polymerase phi DUF647 PF04884.14 KXS14932.1 - 2.9e-50 171.2 0.9 4e-50 170.7 0.9 1.1 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis DUF1206 PF06724.11 KXS14932.1 - 0.55 10.3 10.1 0.18 11.9 3.6 2.7 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1206) F-box-like PF12937.7 KXS14934.1 - 3.1e-09 36.6 0.4 6.7e-09 35.5 0.4 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXS14934.1 - 4.2e-05 23.3 0.2 8.7e-05 22.3 0.2 1.5 1 0 0 1 1 1 1 F-box domain DDE_Tnp_4 PF13359.6 KXS14935.1 - 0.00016 21.4 0.0 0.00019 21.1 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Tna_leader PF08053.11 KXS14935.1 - 0.0038 17.1 0.2 2.8 8.0 0.0 3.6 4 0 0 4 4 4 1 Tryptophanase operon leader peptide Peptidase_C25 PF01364.18 KXS14935.1 - 0.018 14.2 0.0 0.021 14.0 0.0 1.0 1 0 0 1 1 1 0 Peptidase family C25 2OG-FeII_Oxy PF03171.20 KXS14937.1 - 1.2e-19 70.6 0.0 3.7e-19 69.1 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 KXS14937.1 - 1.5e-16 61.2 0.0 2.4e-16 60.6 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal TssN PF17555.2 KXS14939.1 - 0.00081 18.9 1.0 0.00081 18.9 1.0 2.0 2 0 0 2 2 2 1 Type VI secretion system, TssN PalH PF08733.10 KXS14939.1 - 0.0024 16.9 3.0 0.0024 16.9 3.0 2.0 2 0 0 2 2 2 1 PalH/RIM21 DUF2070 PF09843.9 KXS14939.1 - 0.0096 14.3 11.5 0.017 13.4 1.4 2.0 2 0 0 2 2 2 2 Predicted membrane protein (DUF2070) Intg_mem_TP0381 PF09529.10 KXS14939.1 - 0.032 13.8 9.9 0.059 12.9 9.7 1.4 1 1 0 1 1 1 0 Integral membrane protein (intg_mem_TP0381) TMEM208_SND2 PF05620.11 KXS14939.1 - 0.1 12.4 5.8 1.2 8.9 0.2 2.4 2 0 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 DUF2207 PF09972.9 KXS14939.1 - 0.38 9.5 2.4 2.8 6.6 2.4 2.1 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) XK-related PF09815.9 KXS14939.1 - 1.1 8.2 14.0 0.046 12.8 0.9 2.3 2 1 0 2 2 2 0 XK-related protein BatA PF07584.11 KXS14939.1 - 2.7 8.4 5.3 6 7.3 0.5 2.7 3 0 0 3 3 3 0 Aerotolerance regulator N-terminal DUF4153 PF13687.6 KXS14939.1 - 4.4 6.9 15.8 6.9 6.2 6.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4153) DUF4131 PF13567.6 KXS14939.1 - 7.7 6.1 15.5 6.7 6.3 1.5 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) NSP2-B_epitope PF14757.6 KXS14940.1 - 1.7 8.3 6.4 0.066 12.9 0.4 1.6 1 1 1 2 2 2 0 Immunogenic region of nsp2 protein of arterivirus polyprotein WD40 PF00400.32 KXS14941.1 - 1.1e-71 234.9 27.1 1e-11 45.2 0.4 9.1 8 1 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXS14941.1 - 1.2e-29 102.4 0.2 1.2e-06 28.7 0.0 6.4 2 2 5 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KXS14941.1 - 3.5e-14 52.5 0.7 0.0022 17.0 0.0 5.4 3 2 2 6 6 6 4 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 KXS14941.1 - 7.3e-10 38.6 1.3 0.071 12.4 0.0 5.0 3 2 2 5 5 5 3 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 KXS14941.1 - 8.6e-09 34.6 1.8 0.36 9.4 0.0 5.5 2 2 2 6 6 6 3 Nucleoporin Nup120/160 NLE PF08154.12 KXS14941.1 - 9.3e-07 29.3 0.0 1.5e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 NLE (NUC135) domain PD40 PF07676.12 KXS14941.1 - 0.001 18.9 4.5 0.12 12.3 0.0 3.4 4 0 0 4 4 3 2 WD40-like Beta Propeller Repeat Nucleoporin_N PF08801.11 KXS14941.1 - 0.0076 15.0 0.0 4.7 5.8 0.0 3.9 3 2 0 4 4 4 1 Nup133 N terminal like Cytochrom_D1 PF02239.16 KXS14941.1 - 0.011 14.3 0.0 0.036 12.6 0.0 1.9 2 0 0 2 2 2 0 Cytochrome D1 heme domain PALB2_WD40 PF16756.5 KXS14941.1 - 0.02 13.8 3.0 0.26 10.2 0.1 3.5 3 1 1 4 4 4 0 Partner and localizer of BRCA2 WD40 domain Proteasome_A_N PF10584.9 KXS14941.1 - 0.02 14.6 3.4 1.3 8.7 0.0 4.0 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature DHFR_2 PF06442.11 KXS14941.1 - 0.04 13.8 0.0 1.6 8.6 0.0 3.1 2 1 1 3 3 3 0 R67 dihydrofolate reductase WD40_like PF17005.5 KXS14941.1 - 0.21 10.9 0.0 9.8 5.4 0.0 2.9 2 2 1 3 3 3 0 WD40-like domain DUF5570 PF17731.1 KXS14941.1 - 0.27 11.4 3.9 15 5.7 0.0 4.1 2 1 2 4 4 4 0 Family of unknown function (DUF5570) Hexokinase_2 PF03727.16 KXS14942.1 - 5.5e-71 238.8 0.0 7.7e-71 238.3 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 KXS14942.1 - 1.7e-62 210.9 0.0 2.8e-62 210.2 0.0 1.3 1 0 0 1 1 1 1 Hexokinase DUF348 PF03990.14 KXS14942.1 - 0.068 12.9 0.6 4.2 7.2 0.0 3.3 4 0 0 4 4 4 0 G5-linked-Ubiquitin-like domain VPS9 PF02204.18 KXS14943.1 - 7e-20 71.2 0.0 3.1e-19 69.1 0.0 1.9 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain DDE_Tnp_4 PF13359.6 KXS14944.1 - 5.7e-19 68.3 0.0 7.6e-19 67.9 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Peptidase_C25 PF01364.18 KXS14944.1 - 0.027 13.7 0.0 0.039 13.1 0.0 1.2 1 0 0 1 1 1 0 Peptidase family C25 CBM_35 PF16990.5 KXS14944.1 - 0.039 14.2 0.1 0.18 12.1 0.0 2.1 2 1 0 2 2 2 0 Carbohydrate binding module (family 35) Guanylate_cyc PF00211.20 KXS14946.1 - 2e-17 63.4 0.0 3.4e-17 62.7 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain TerB_N PF13208.6 KXS14947.1 - 0.032 13.9 0.0 0.035 13.8 0.0 1.0 1 0 0 1 1 1 0 TerB N-terminal domain Rod_cone_degen PF15201.6 KXS14948.1 - 0.00092 19.3 0.2 0.00092 19.3 0.2 2.0 2 0 0 2 2 2 1 Progressive rod-cone degeneration adh_short PF00106.25 KXS14949.1 - 2.7e-21 75.9 0.1 1.5e-17 63.7 0.1 2.2 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXS14949.1 - 2.3e-20 73.2 0.1 1.5e-18 67.2 0.1 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXS14949.1 - 0.0018 18.2 0.0 0.0029 17.5 0.0 1.3 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 KXS14949.1 - 0.02 13.9 0.1 0.035 13.1 0.1 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family BKACE PF05853.12 KXS14949.1 - 0.092 12.0 0.1 0.12 11.7 0.1 1.2 1 0 0 1 1 1 0 beta-keto acid cleavage enzyme MFS_1 PF07690.16 KXS14951.1 - 4e-31 108.2 79.2 3.1e-27 95.4 42.5 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2070 PF09843.9 KXS14951.1 - 7 4.8 7.5 11 4.1 7.5 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Abhydrolase_6 PF12697.7 KXS14952.1 - 9.8e-08 32.9 0.0 1.3e-07 32.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXS14952.1 - 1.1e-06 28.6 0.0 1.3e-06 28.2 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXS14952.1 - 0.039 13.2 0.0 0.047 12.9 0.0 1.1 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Thioesterase PF00975.20 KXS14952.1 - 0.061 13.4 0.0 0.078 13.1 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain zf-C2H2_aberr PF17017.5 KXS14955.1 - 0.0097 16.1 0.6 0.016 15.4 0.6 1.2 1 0 0 1 1 1 1 Aberrant zinc-finger zf-C2H2 PF00096.26 KXS14955.1 - 0.41 11.2 4.3 1.1 9.9 0.0 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF4663 PF15668.5 KXS14955.1 - 0.47 9.5 3.9 0.87 8.6 3.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4663) Lipase_GDSL_2 PF13472.6 KXS14956.1 - 8.2e-15 55.7 0.0 9.7e-15 55.4 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KXS14956.1 - 6.7e-05 23.0 0.0 0.00013 22.0 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase LtrA PF06772.11 KXS14957.1 - 4.1e-35 121.6 27.1 5.1e-34 118.0 27.3 2.2 1 1 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) MASE3 PF17159.4 KXS14957.1 - 7.2 6.2 21.2 0.035 13.7 6.3 3.2 2 1 0 3 3 3 0 Membrane-associated sensor domain DUF1264 PF06884.11 KXS14958.1 - 3.4e-19 69.1 0.0 3.9e-19 68.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1264) adh_short PF00106.25 KXS14960.1 - 4.5e-31 107.8 0.0 6.5e-31 107.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXS14960.1 - 5.5e-26 91.6 0.0 8.2e-26 91.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXS14960.1 - 2.9e-06 27.3 0.0 4.5e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 KR domain Serglycin PF04360.12 KXS14961.1 - 0.13 12.2 5.8 0.042 13.8 2.9 1.7 2 0 0 2 2 2 0 Serglycin Phosphoesterase PF04185.14 KXS14963.1 - 4.6e-20 72.1 0.0 1.7e-18 67.0 0.0 2.3 2 1 0 2 2 2 1 Phosphoesterase family PITH PF06201.13 KXS14964.1 - 1.8e-32 112.7 0.0 4.5e-32 111.4 0.0 1.6 2 0 0 2 2 2 1 PITH domain Thioredoxin PF00085.20 KXS14964.1 - 3.9e-27 94.2 0.1 7.1e-27 93.4 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KXS14964.1 - 2.5e-06 27.9 0.2 2.9e-05 24.5 0.2 2.5 2 1 0 2 2 2 1 Thioredoxin-like domain OST3_OST6 PF04756.13 KXS14964.1 - 0.00038 19.9 0.0 0.00057 19.3 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 KXS14964.1 - 0.0011 19.3 0.0 0.0023 18.2 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.6 KXS14964.1 - 0.0021 17.8 0.0 0.0035 17.1 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 KXS14964.1 - 0.0088 16.2 0.0 0.019 15.2 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 KXS14964.1 - 0.095 12.4 0.1 0.28 10.9 0.1 1.7 1 1 0 1 1 1 0 Redoxin adh_short_C2 PF13561.6 KXS14965.1 - 1.9e-51 174.9 0.9 2.2e-51 174.7 0.9 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXS14965.1 - 4.5e-41 140.5 0.2 5.3e-41 140.2 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 KXS14965.1 - 0.00084 18.9 0.1 0.0017 17.9 0.1 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXS14965.1 - 0.016 14.2 0.1 0.021 13.8 0.1 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 KXS14965.1 - 0.021 14.7 2.5 0.096 12.6 2.5 2.2 1 1 0 1 1 1 0 KR domain NUDIX PF00293.28 KXS14965.1 - 0.066 13.3 0.0 0.17 11.9 0.0 1.6 2 0 0 2 2 2 0 NUDIX domain NAD_binding_7 PF13241.6 KXS14965.1 - 0.12 12.8 0.2 0.27 11.7 0.2 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding cNMP_binding PF00027.29 KXS14966.1 - 2.5e-19 69.1 0.0 3.1e-19 68.8 0.0 1.1 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain LMBR1 PF04791.16 KXS14967.1 - 1.7e-18 66.9 17.4 3e-17 62.7 7.3 2.3 1 1 0 2 2 2 2 LMBR1-like membrane protein GPI2 PF06432.11 KXS14967.1 - 7.4 5.9 12.5 7.5 5.9 1.7 3.8 2 2 2 4 4 4 0 Phosphatidylinositol N-acetylglucosaminyltransferase Y_Y_Y PF07495.13 KXS14968.1 - 0.0017 18.3 0.0 0.0048 16.8 0.0 1.8 1 0 0 1 1 1 1 Y_Y_Y domain Oxidored_molyb PF00174.19 KXS14968.1 - 0.004 16.8 0.0 2.9 7.5 0.0 2.7 2 1 1 3 3 3 2 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 KXS14968.1 - 0.084 12.9 0.0 0.22 11.5 0.0 1.7 1 1 0 1 1 1 0 Mo-co oxidoreductase dimerisation domain DUF383 PF04063.14 KXS14969.1 - 9.8e-54 181.9 0.0 2.4e-53 180.6 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF383) DUF384 PF04064.13 KXS14969.1 - 5.4e-18 64.6 1.3 1.2e-17 63.5 1.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF384) HEAT_2 PF13646.6 KXS14969.1 - 0.0038 17.6 0.1 0.19 12.2 0.0 3.1 3 1 0 3 3 3 1 HEAT repeats Cnd1 PF12717.7 KXS14969.1 - 0.017 15.1 0.1 0.11 12.6 0.1 2.2 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 KXS14969.1 - 0.13 12.8 0.1 2.3 8.8 0.0 3.2 3 0 0 3 3 3 0 HEAT-like repeat CwfJ_C_2 PF04676.14 KXS14970.1 - 8.3e-28 97.2 0.9 1.8e-27 96.1 0.9 1.6 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 CwfJ_C_1 PF04677.15 KXS14970.1 - 4.4e-17 62.1 0.0 6.7e-17 61.5 0.0 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 MPP6 PF10175.9 KXS14970.1 - 0.099 13.1 0.1 0.24 11.9 0.1 1.6 1 0 0 1 1 1 0 M-phase phosphoprotein 6 F-box PF00646.33 KXS14971.1 - 0.0084 16.0 0.2 0.02 14.8 0.2 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KXS14971.1 - 0.043 13.7 2.8 0.066 13.1 0.2 2.6 2 0 0 2 2 2 0 F-box-like SH3BP5 PF05276.14 KXS14971.1 - 0.15 11.8 0.1 0.22 11.3 0.1 1.1 1 0 0 1 1 1 0 SH3 domain-binding protein 5 (SH3BP5) DUF1970 PF09301.10 KXS14972.1 - 0.61 10.4 3.2 0.83 9.9 3.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1970) F-box PF00646.33 KXS14973.1 - 0.00011 22.0 0.2 0.00011 22.0 0.2 2.1 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KXS14973.1 - 0.00014 21.6 1.2 0.00059 19.7 1.2 2.2 1 0 0 1 1 1 1 F-box-like 2OG-FeII_Oxy_4 PF13661.6 KXS14975.1 - 3.1e-08 34.2 0.0 6e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 KXS14975.1 - 2.5e-05 25.1 0.3 9.2e-05 23.3 0.3 1.9 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily cobW PF02492.19 KXS14976.1 - 3.3e-33 114.7 0.0 4.2e-33 114.4 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 KXS14976.1 - 0.0011 18.1 0.2 0.92 8.4 0.0 2.1 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 KXS14976.1 - 0.0033 17.5 0.0 0.0087 16.1 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KXS14976.1 - 0.013 15.9 0.0 0.019 15.3 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain ResIII PF04851.15 KXS14976.1 - 0.049 13.6 0.0 0.068 13.2 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_18 PF13238.6 KXS14976.1 - 0.056 14.0 0.0 0.092 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 KXS14976.1 - 0.069 12.3 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain ABC_tran PF00005.27 KXS14976.1 - 0.098 13.2 0.0 0.14 12.6 0.0 1.3 1 0 0 1 1 1 0 ABC transporter ATPase_2 PF01637.18 KXS14976.1 - 0.14 12.1 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_7 PF12775.7 KXS14976.1 - 0.15 11.6 0.0 0.22 11.0 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region Pox_A32 PF04665.12 KXS14976.1 - 0.19 11.1 0.0 0.27 10.6 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein NACHT PF05729.12 KXS14976.1 - 0.2 11.6 0.0 0.31 10.9 0.0 1.3 1 0 0 1 1 1 0 NACHT domain cNMP_binding PF00027.29 KXS14977.1 - 5.5e-43 144.9 0.1 1.2e-20 73.4 0.0 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.17 KXS14977.1 - 4.9e-05 22.9 0.0 9.1e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit CDP-OH_P_transf PF01066.21 KXS14978.1 - 4.7e-16 59.3 0.1 4.7e-16 59.3 0.1 3.2 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase YjcZ_2 PF09680.10 KXS14978.1 - 0.21 11.3 3.6 0.57 9.9 3.6 1.8 1 0 0 1 1 1 0 Family of unknown function CTK3_C PF12350.8 KXS14981.1 - 1.9e-06 27.9 3.0 3.8e-06 27.0 3.0 1.6 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 C-terminus HTH_36 PF13730.6 KXS14981.1 - 0.015 15.2 0.0 0.032 14.2 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain CTK3 PF12243.8 KXS14981.1 - 0.041 13.9 0.0 0.056 13.4 0.0 1.2 1 0 0 1 1 1 0 CTD kinase subunit gamma CTK3 DnaJ PF00226.31 KXS14983.1 - 2.7e-12 46.6 1.4 5.7e-12 45.6 1.4 1.6 1 0 0 1 1 1 1 DnaJ domain PTPRCAP PF15713.5 KXS14983.1 - 0.02 15.2 5.5 0.036 14.4 5.5 1.3 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated EOS1 PF12326.8 KXS14983.1 - 0.051 13.5 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 N-glycosylation protein SID-1_RNA_chan PF13965.6 KXS14983.1 - 0.14 10.5 0.7 0.28 9.5 0.7 1.5 1 1 0 1 1 1 0 dsRNA-gated channel SID-1 GTA_holin_3TM PF11351.8 KXS14983.1 - 0.2 12.2 0.8 0.45 11.1 0.8 1.6 1 0 0 1 1 1 0 Holin of 3TMs, for gene-transfer release CPSF100_C PF13299.6 KXS14983.1 - 0.35 11.0 6.0 0.7 10.1 4.2 2.1 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal NPR3 PF03666.13 KXS14983.1 - 0.4 9.4 4.8 0.44 9.3 3.1 1.8 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 Connexin PF00029.19 KXS14983.1 - 0.64 9.7 2.9 0.25 11.1 0.6 1.6 2 0 0 2 2 2 0 Connexin Presenilin PF01080.17 KXS14983.1 - 0.7 8.6 3.4 1.6 7.5 3.4 1.5 1 0 0 1 1 1 0 Presenilin Rrn6 PF10214.9 KXS14983.1 - 0.79 8.1 7.5 1.1 7.6 7.5 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor CDC45 PF02724.14 KXS14983.1 - 8.9 4.5 9.4 13 4.0 9.4 1.1 1 0 0 1 1 1 0 CDC45-like protein CorA PF01544.18 KXS14984.1 - 9.3e-39 133.5 2.6 6e-33 114.4 1.2 2.1 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein Pox_A11 PF05061.13 KXS14984.1 - 0.18 11.1 0.0 10 5.3 0.0 2.2 2 0 0 2 2 2 0 Poxvirus A11 Protein Dus PF01207.17 KXS14985.1 - 1.3e-77 261.0 0.0 1.5e-77 260.8 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) NMO PF03060.15 KXS14985.1 - 7.9e-05 22.2 0.0 0.00011 21.8 0.0 1.3 1 1 0 1 1 1 1 Nitronate monooxygenase SOR_SNZ PF01680.17 KXS14985.1 - 0.0005 19.9 0.4 0.03 14.1 0.0 2.2 1 1 1 2 2 2 1 SOR/SNZ family DHO_dh PF01180.21 KXS14985.1 - 0.00057 19.2 0.0 0.045 13.0 0.0 2.1 2 0 0 2 2 2 1 Dihydroorotate dehydrogenase G3P_antiterm PF04309.12 KXS14985.1 - 0.0052 16.2 0.0 0.0086 15.5 0.0 1.3 1 0 0 1 1 1 1 Glycerol-3-phosphate responsive antiterminator His_biosynth PF00977.21 KXS14985.1 - 0.01 15.3 0.1 0.043 13.3 0.1 1.9 1 1 0 1 1 1 0 Histidine biosynthesis protein ThiG PF05690.14 KXS14985.1 - 0.011 15.1 0.0 0.019 14.3 0.0 1.4 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG IMPDH PF00478.25 KXS14985.1 - 0.02 13.9 0.0 0.041 12.9 0.0 1.5 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KXS14985.1 - 0.15 11.0 0.0 0.23 10.4 0.0 1.3 1 0 0 1 1 1 0 FMN-dependent dehydrogenase LRR_6 PF13516.6 KXS14986.1 - 2.4e-06 27.2 0.2 2.4 8.4 0.0 6.0 7 0 0 7 7 7 3 Leucine Rich repeat STAS_2 PF13466.6 KXS14986.1 - 0.089 13.1 0.2 0.5 10.7 0.0 2.3 2 0 0 2 2 2 0 STAS domain Apolipoprotein PF01442.18 KXS14987.1 - 0.012 15.4 2.9 0.016 15.1 1.7 1.7 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain Snapin_Pallidin PF14712.6 KXS14987.1 - 0.88 10.0 4.4 2.1 8.8 4.4 1.6 1 0 0 1 1 1 0 Snapin/Pallidin SNF2_N PF00176.23 KXS14988.1 - 1.4e-58 198.3 0.0 1.6e-47 161.9 0.0 3.0 2 1 1 3 3 3 2 SNF2 family N-terminal domain Helicase_C PF00271.31 KXS14988.1 - 2.5e-17 63.2 0.0 1.7e-16 60.6 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KXS14988.1 - 4.2e-07 29.9 0.0 8.5e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KXS14988.1 - 5.2e-07 29.8 0.4 1.6e-06 28.2 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.25 KXS14988.1 - 2e-06 27.6 5.2 2e-06 27.6 5.2 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KXS14988.1 - 3.9e-06 26.6 3.1 3.9e-06 26.6 3.1 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXS14988.1 - 8.2e-05 22.5 3.7 8.2e-05 22.5 3.7 2.1 2 0 0 2 2 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KXS14988.1 - 9.7e-05 22.3 1.6 0.00023 21.1 0.4 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KXS14988.1 - 0.00023 20.9 3.7 0.00023 20.9 3.7 2.6 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXS14988.1 - 0.00083 19.6 4.0 0.00083 19.6 4.0 2.2 2 0 0 2 2 1 1 Ring finger domain zf-Nse PF11789.8 KXS14988.1 - 0.0075 16.1 2.0 0.016 15.0 2.0 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.6 KXS14988.1 - 0.01 15.6 3.6 0.01 15.6 3.6 1.9 2 0 0 2 2 1 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KXS14988.1 - 0.3 11.3 5.0 0.83 9.9 5.0 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Herpes_BLLF1 PF05109.13 KXS14990.1 - 4.8 5.0 21.5 6.3 4.6 21.5 1.2 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) Tic110 PF16940.5 KXS14990.1 - 8.8 4.7 5.0 13 4.1 5.0 1.1 1 0 0 1 1 1 0 Chloroplast envelope transporter DPBB_1 PF03330.18 KXS14991.1 - 0.08 13.2 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 Lytic transglycolase Mito_fiss_reg PF05308.11 KXS14992.1 - 0.0061 16.7 4.8 0.0061 16.7 4.8 2.1 2 0 0 2 2 2 1 Mitochondrial fission regulator Pex14_N PF04695.13 KXS14992.1 - 0.14 12.8 6.2 4.1 8.0 5.6 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Transglut_core PF01841.19 KXS14993.1 - 2.3e-14 53.8 0.4 4.1e-14 53.0 0.4 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily Rad4 PF03835.15 KXS14993.1 - 6.2e-06 26.0 1.2 1.6e-05 24.6 0.7 1.8 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain CT_C_D PF02682.16 KXS14993.1 - 0.099 12.4 0.0 0.19 11.5 0.0 1.4 2 0 0 2 2 2 0 Carboxyltransferase domain, subdomain C and D PHP PF02811.19 KXS14995.1 - 4.3e-07 30.4 0.2 8.1e-07 29.5 0.2 1.6 1 1 0 1 1 1 1 PHP domain UQ_con PF00179.26 KXS14996.1 - 4e-47 159.4 0.0 4.7e-47 159.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Pcc1 PF09341.10 KXS14997.1 - 3.5e-20 71.9 0.1 4e-20 71.7 0.1 1.1 1 0 0 1 1 1 1 Transcription factor Pcc1 DUF3128 PF11326.8 KXS14998.1 - 3.5e-19 68.9 2.1 4.2e-19 68.7 2.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) SPATA3 PF15662.5 KXS14998.1 - 0.025 15.2 0.1 0.03 15.0 0.1 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated protein 3 family ERGIC_N PF13850.6 KXS14999.1 - 1.2e-14 54.3 0.1 2e-14 53.7 0.1 1.2 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) COPIIcoated_ERV PF07970.12 KXS14999.1 - 7.4e-08 32.5 0.1 1.3e-07 31.7 0.1 1.4 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter DUF2406 PF10295.9 KXS15000.1 - 0.12 13.0 0.2 0.22 12.2 0.2 1.4 1 0 0 1 1 1 0 Uncharacterised protein (DUF2406) Myosin_head PF00063.21 KXS15001.1 - 5.2e-201 669.4 0.0 6.8e-201 669.0 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) DIL PF01843.19 KXS15001.1 - 5.9e-17 61.9 0.0 1.2e-16 60.8 0.0 1.6 1 0 0 1 1 1 1 DIL domain AAA_22 PF13401.6 KXS15001.1 - 0.018 15.3 0.0 0.052 13.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain Myosin_N PF02736.19 KXS15001.1 - 0.3 10.9 2.4 0.22 11.4 0.2 2.0 2 0 0 2 2 2 0 Myosin N-terminal SH3-like domain DDE_1 PF03184.19 KXS15002.1 - 1.1e-12 48.0 0.1 1.2e-12 47.9 0.1 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease CoxIIa PF08113.11 KXS15003.1 - 0.028 14.2 0.3 0.044 13.6 0.3 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IIa family PGM_PMM_I PF02878.16 KXS15004.1 - 1.8e-34 118.4 0.1 2.9e-34 117.7 0.1 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 KXS15004.1 - 2.9e-27 95.1 0.0 6e-27 94.1 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 KXS15004.1 - 4e-16 59.5 0.0 1.1e-15 58.1 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 KXS15004.1 - 1.6e-08 34.6 0.1 3.8e-08 33.4 0.1 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain WW PF00397.26 KXS15005.1 - 1.9e-12 47.0 0.7 2.9e-12 46.4 0.7 1.3 1 0 0 1 1 1 1 WW domain DUF2076 PF09849.9 KXS15005.1 - 0.00048 20.3 1.2 0.00051 20.2 1.2 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) Chorion_3 PF05387.11 KXS15005.1 - 0.16 11.6 11.5 0.21 11.2 11.5 1.2 1 0 0 1 1 1 0 Chorion family 3 MMgT PF10270.9 KXS15006.1 - 4.9e-14 52.5 0.0 6.4e-14 52.1 0.0 1.2 1 0 0 1 1 1 1 Membrane magnesium transporter Glycos_transf_3 PF00591.21 KXS15007.1 - 6.1e-85 284.8 0.0 9.4e-85 284.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 KXS15007.1 - 2.6e-08 33.6 0.1 4.4e-08 32.9 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain Glyco_hydro_88 PF07470.13 KXS15012.1 - 8.7e-28 97.4 0.1 1e-27 97.1 0.1 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Proteasome PF00227.26 KXS15014.1 - 5.1e-38 130.5 0.0 6.2e-38 130.2 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome PF00227.26 KXS15015.1 - 5.7e-46 156.4 0.3 6.9e-46 156.1 0.3 1.0 1 0 0 1 1 1 1 Proteasome subunit Cerato-platanin PF07249.12 KXS15016.1 - 1.7e-07 31.3 0.1 2.1e-07 31.1 0.1 1.1 1 0 0 1 1 1 1 Cerato-platanin DPBB_1 PF03330.18 KXS15016.1 - 0.00021 21.5 0.1 0.00034 20.9 0.1 1.4 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 KXS15016.1 - 0.0057 16.5 0.0 0.0065 16.3 0.0 1.1 1 0 0 1 1 1 1 Barwin family TFIIB PF00382.19 KXS15017.1 - 8.4e-08 32.2 0.1 0.017 15.2 0.1 2.6 2 1 0 2 2 2 2 Transcription factor TFIIB repeat HATPase_c PF02518.26 KXS15018.1 - 1.8e-26 92.9 0.1 7.3e-26 90.9 0.0 2.1 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KXS15018.1 - 8.1e-19 67.9 0.0 3.4e-18 65.8 0.0 2.0 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 KXS15018.1 - 5.6e-17 61.5 0.3 1.6e-16 60.1 0.3 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain TerB_C PF15615.6 KXS15018.1 - 0.13 12.6 1.6 0.99 9.7 0.0 2.3 2 0 0 2 2 2 0 TerB-C domain RNA_pol_Rpb1_R PF05001.13 KXS15018.1 - 4.7 7.7 7.3 27 5.4 0.3 2.5 2 0 0 2 2 2 0 RNA polymerase Rpb1 C-terminal repeat GATase PF00117.28 KXS15019.1 - 1.8e-12 47.4 0.1 2.1e-12 47.2 0.1 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KXS15019.1 - 0.098 12.4 0.9 2.3 7.9 0.1 2.8 1 1 2 3 3 3 0 Peptidase C26 FAD_binding_3 PF01494.19 KXS15020.1 - 9.8e-20 71.1 0.0 1.9e-19 70.2 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KXS15020.1 - 2.4e-05 24.5 0.7 5.3e-05 23.4 0.7 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KXS15020.1 - 5.1e-05 22.5 1.6 9.7e-05 21.6 1.6 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KXS15020.1 - 0.00036 19.9 1.7 0.019 14.2 0.7 2.3 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KXS15020.1 - 0.0022 17.4 2.4 0.0038 16.6 2.4 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KXS15020.1 - 0.012 14.8 1.8 0.16 11.2 1.8 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXS15020.1 - 0.013 16.0 0.5 7.4 7.2 1.1 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KXS15020.1 - 0.028 13.7 0.4 2.5 7.3 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase GIDA PF01134.22 KXS15020.1 - 0.047 12.8 1.4 0.076 12.1 1.4 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A DUF4333 PF14230.6 KXS15020.1 - 0.049 13.9 0.0 0.093 13.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4333) HI0933_like PF03486.14 KXS15020.1 - 0.081 11.6 0.8 0.8 8.3 0.3 2.0 2 0 0 2 2 2 0 HI0933-like protein DAO PF01266.24 KXS15020.1 - 0.22 11.0 6.0 0.71 9.4 5.6 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase Cerato-platanin PF07249.12 KXS15021.1 - 5.9e-14 52.2 0.7 5.9e-14 52.2 0.7 2.2 3 0 0 3 3 3 1 Cerato-platanin Barwin PF00967.17 KXS15021.1 - 2.1e-05 24.4 1.9 2.9e-05 23.9 0.1 2.1 2 0 0 2 2 2 1 Barwin family ETRAMP PF09716.10 KXS15021.1 - 0.1 12.6 0.1 0.17 12.0 0.1 1.3 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Dynactin_p62 PF05502.13 KXS15022.1 - 4.6e-20 71.9 9.3 5.6e-20 71.6 9.3 1.1 1 0 0 1 1 1 1 Dynactin p62 family Rrn6 PF10214.9 KXS15023.1 - 0.27 9.7 0.0 0.38 9.2 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor AMPK1_CBM PF16561.5 KXS15024.1 - 3e-33 113.9 0.0 5.2e-33 113.1 0.0 1.3 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase AMPKBI PF04739.15 KXS15024.1 - 3.4e-24 84.9 3.1 1.1e-23 83.3 3.1 1.9 1 0 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interaction domain CBM53 PF16760.5 KXS15024.1 - 0.013 16.1 0.0 0.048 14.2 0.0 1.9 2 0 0 2 2 2 0 Starch/carbohydrate-binding module (family 53) Abhydrolase_3 PF07859.13 KXS15026.1 - 9.9e-43 146.4 0.0 7.1e-35 120.8 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KXS15026.1 - 6.1e-09 35.2 0.0 0.00016 20.6 0.0 2.1 2 0 0 2 2 2 2 Steryl acetyl hydrolase COesterase PF00135.28 KXS15026.1 - 0.0014 17.6 0.0 0.0046 15.9 0.0 1.7 2 0 0 2 2 2 1 Carboxylesterase family Lactamase_B PF00753.27 KXS15027.1 - 9.2e-20 71.5 1.2 1.6e-19 70.7 1.2 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily BLACT_WH PF17778.1 KXS15027.1 - 3.4e-13 49.3 0.6 7.4e-13 48.3 0.6 1.6 1 0 0 1 1 1 1 Beta-lactamase associated winged helix domain Lactamase_B_2 PF12706.7 KXS15027.1 - 7e-09 35.5 0.1 1e-08 34.9 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_6 PF16661.5 KXS15027.1 - 0.17 11.3 0.0 0.29 10.5 0.0 1.4 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily domain PEX11 PF05648.14 KXS15028.1 - 4.8e-17 62.2 0.0 1.5e-15 57.3 0.0 2.1 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Exo70 PF03081.15 KXS15029.1 - 1.1e-75 255.1 0.0 3.2e-75 253.5 0.0 1.7 2 0 0 2 2 2 1 Exo70 exocyst complex subunit COG6 PF06419.11 KXS15029.1 - 0.0068 14.7 2.4 0.41 8.8 0.2 2.8 2 2 1 3 3 3 2 Conserved oligomeric complex COG6 APG17 PF04108.12 KXS15029.1 - 0.014 14.5 0.3 0.078 12.1 0.4 2.0 2 0 0 2 2 2 0 Autophagy protein Apg17 Vps52 PF04129.12 KXS15029.1 - 0.12 11.1 1.9 2 7.1 0.5 2.2 2 0 0 2 2 2 0 Vps52 / Sac2 family KLRAQ PF10205.9 KXS15029.1 - 0.13 12.5 0.2 0.33 11.2 0.2 1.6 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein YTH PF04146.15 KXS15030.1 - 1.9e-32 112.5 0.0 5.8e-32 110.9 0.0 1.8 2 1 0 2 2 2 1 YT521-B-like domain RRM_1 PF00076.22 KXS15030.1 - 4.3e-06 26.5 0.0 7.6e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 6PF2K PF01591.18 KXS15031.1 - 1.1e-70 237.5 0.0 1.7e-70 236.8 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 KXS15031.1 - 1.3e-36 126.1 0.0 1.4e-35 122.7 0.0 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 KXS15031.1 - 0.00049 20.3 0.1 0.0011 19.2 0.1 1.7 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.10 KXS15031.1 - 0.0022 17.5 0.0 0.0038 16.7 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 Oxidored_FMN PF00724.20 KXS15032.1 - 1.1e-53 182.7 0.0 1.4e-53 182.3 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Myb_Cef PF11831.8 KXS15037.1 - 0.16 11.5 0.0 4.7 6.7 0.0 2.6 2 0 0 2 2 2 0 pre-mRNA splicing factor component Ank_2 PF12796.7 KXS15040.1 - 0.00057 20.4 0.1 0.0011 19.5 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) HlyIII PF03006.20 KXS15041.1 - 1.2e-56 192.0 22.5 1.5e-56 191.6 22.5 1.2 1 0 0 1 1 1 1 Haemolysin-III related GREB1 PF15782.5 KXS15042.1 - 0.42 7.7 19.0 0.55 7.3 19.0 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SOBP PF15279.6 KXS15042.1 - 2.4 8.7 22.9 3.7 8.1 22.9 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein Fungal_trans PF04082.18 KXS15046.1 - 9.4e-07 28.1 0.0 1.7e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Flg_hook PF02120.16 KXS15047.1 - 0.00034 20.5 2.7 0.035 14.0 0.3 2.2 1 1 0 2 2 2 2 Flagellar hook-length control protein FliK Bactofilin PF04519.13 KXS15047.1 - 0.00037 20.7 1.0 0.06 13.6 0.3 2.1 1 1 0 2 2 2 1 Polymer-forming cytoskeletal Serpin PF00079.20 KXS15047.1 - 0.034 13.5 0.4 0.039 13.3 0.4 1.1 1 0 0 1 1 1 0 Serpin (serine protease inhibitor) CCDC-167 PF15188.6 KXS15047.1 - 0.13 12.6 8.8 0.52 10.7 1.3 2.2 1 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 FliT PF05400.13 KXS15047.1 - 0.23 12.3 8.7 1.1 10.1 1.1 2.1 1 1 1 2 2 2 0 Flagellar protein FliT Apolipoprotein PF01442.18 KXS15047.1 - 0.31 10.9 7.4 0.96 9.3 7.4 1.6 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Fzo_mitofusin PF04799.13 KXS15047.1 - 0.78 9.3 3.7 1.2 8.6 0.6 1.9 1 1 1 2 2 2 0 fzo-like conserved region OmpH PF03938.14 KXS15047.1 - 0.84 10.0 14.6 1.9 8.8 3.1 2.0 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) PLAC9 PF15205.6 KXS15047.1 - 0.89 10.0 7.4 9.8 6.7 0.5 3.0 1 1 2 3 3 3 0 Placenta-specific protein 9 Phage_GP20 PF06810.11 KXS15047.1 - 1.2 8.9 11.0 6 6.7 11.2 1.8 1 1 0 1 1 1 0 Phage minor structural protein GP20 DivIC PF04977.15 KXS15047.1 - 2.1 8.1 8.8 4.7 7.1 0.3 2.4 2 1 0 2 2 2 0 Septum formation initiator Anti-adapt_IraP PF10796.9 KXS15047.1 - 4.4 7.9 7.8 3.3 8.3 3.8 2.0 1 1 1 2 2 2 0 Sigma-S stabilisation anti-adaptor protein HSCB_C PF07743.13 KXS15047.1 - 4.7 7.8 12.8 2e+03 -0.6 12.8 2.5 1 1 0 1 1 1 0 HSCB C-terminal oligomerisation domain GST_N_4 PF17172.4 KXS15049.1 - 1.6e-15 57.7 0.0 3.1e-15 56.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 KXS15049.1 - 3.9e-13 49.0 0.0 8e-13 48.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KXS15049.1 - 1.3e-05 25.1 0.1 4.7e-05 23.3 0.1 2.0 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 KXS15049.1 - 0.00016 22.0 0.0 0.00027 21.2 0.0 1.4 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C PF00043.25 KXS15049.1 - 0.11 12.7 0.0 0.45 10.8 0.0 2.0 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain zf-RING_2 PF13639.6 KXS15050.1 - 3.5e-07 30.5 15.8 7.4e-06 26.2 6.7 3.7 3 1 0 3 3 3 2 Ring finger domain zf-RING_UBOX PF13445.6 KXS15050.1 - 4.8e-07 29.7 3.9 6.1e-07 29.4 0.1 3.0 2 1 1 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KXS15050.1 - 1e-06 28.5 9.1 1.1e-05 25.2 1.3 3.8 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KXS15050.1 - 1.3e-06 28.6 8.5 2.5e-06 27.7 1.5 2.9 3 0 0 3 3 3 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KXS15050.1 - 2.3e-05 24.3 2.0 2.3e-05 24.3 2.0 3.0 3 0 0 3 3 3 1 zinc-RING finger domain IQ PF00612.27 KXS15050.1 - 2.7e-05 23.6 3.1 4.7e-05 22.8 1.3 2.5 2 0 0 2 2 2 1 IQ calmodulin-binding motif zf-C3HC4_3 PF13920.6 KXS15050.1 - 8.4e-05 22.3 12.3 0.0028 17.5 0.9 3.5 4 0 0 4 4 3 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KXS15050.1 - 0.00017 21.3 6.5 0.0054 16.6 0.2 3.1 3 0 0 3 3 3 2 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KXS15050.1 - 0.00081 19.4 3.8 0.0022 18.0 1.0 2.7 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 KXS15050.1 - 0.0025 17.6 1.0 0.0025 17.6 1.0 4.2 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KXS15050.1 - 0.057 13.2 0.1 0.057 13.2 0.1 3.6 5 0 0 5 5 4 0 RING-like zinc finger Mer2 PF09074.10 KXS15050.1 - 0.15 11.8 0.4 0.23 11.3 0.4 1.2 1 0 0 1 1 1 0 Mer2 zf-UDP PF14569.6 KXS15050.1 - 0.23 11.6 5.2 3.6 7.8 0.2 2.7 3 0 0 3 3 3 0 Zinc-binding RING-finger zf-RING_4 PF14570.6 KXS15050.1 - 0.44 10.4 11.2 0.37 10.6 1.0 2.8 3 0 0 3 3 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_5 PF17121.5 KXS15050.1 - 0.84 9.6 5.1 24 4.9 0.1 2.9 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-P11 PF03854.14 KXS15050.1 - 1 9.0 8.8 8.2 6.2 1.1 3.3 3 0 0 3 3 3 0 P-11 zinc finger RecR PF02132.15 KXS15050.1 - 2.3 7.8 6.1 24 4.6 0.3 3.9 4 0 0 4 4 4 0 RecR protein zf-RING-like PF08746.11 KXS15050.1 - 3.9 7.9 11.1 1.7 9.0 1.8 2.9 3 0 0 3 3 3 0 RING-like domain zf-RING_2 PF13639.6 KXS15051.1 - 4.2e-05 23.8 1.2 4.2e-05 23.8 1.2 1.5 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 KXS15051.1 - 0.00024 21.1 1.6 0.00045 20.2 0.8 1.9 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_11 PF17123.5 KXS15051.1 - 0.00028 20.5 0.4 0.00067 19.4 0.4 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_5 PF14634.6 KXS15051.1 - 0.017 15.0 4.2 0.033 14.1 3.2 1.8 1 1 1 2 2 2 0 zinc-RING finger domain zf-C3HC4 PF00097.25 KXS15051.1 - 0.024 14.5 0.1 0.053 13.4 0.1 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KXS15051.1 - 0.057 13.3 5.6 0.1 12.5 0.8 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 KXS15051.1 - 0.12 12.2 5.4 0.27 11.1 4.4 2.0 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Ribosomal_L36 PF00444.18 KXS15052.1 - 1.6e-05 25.0 4.7 1.6e-05 25.0 4.7 1.9 2 0 0 2 2 2 1 Ribosomal protein L36 PI3_PI4_kinase PF00454.27 KXS15053.1 - 7.9e-51 173.3 0.0 1.2e-50 172.7 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 KXS15053.1 - 9e-10 38.3 0.8 1.6e-09 37.4 0.8 1.3 1 0 0 1 1 1 1 FAT domain FATC PF02260.20 KXS15053.1 - 3.5e-07 29.9 0.1 8.5e-07 28.7 0.1 1.6 1 0 0 1 1 1 1 FATC domain TAN PF11640.8 KXS15054.1 - 7.9e-11 42.3 0.3 2.4e-09 37.5 0.2 2.6 2 0 0 2 2 2 1 Telomere-length maintenance and DNA damage repair IFRD PF05004.13 KXS15054.1 - 1.8e-06 27.3 1.3 0.00022 20.4 0.0 3.2 3 1 1 4 4 4 2 Interferon-related developmental regulator (IFRD) Amino_oxidase PF01593.24 KXS15056.1 - 1.3e-29 103.8 0.0 1.8e-29 103.3 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KXS15056.1 - 4.4e-12 46.0 0.0 1.4e-11 44.4 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXS15056.1 - 1.1e-08 35.1 0.0 1.7e-06 27.9 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KXS15056.1 - 2.1e-05 24.6 0.1 0.0055 16.7 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KXS15056.1 - 0.00077 18.8 0.0 0.0042 16.3 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KXS15056.1 - 0.046 12.6 0.0 0.075 11.9 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase Thi4 PF01946.17 KXS15056.1 - 0.16 11.2 0.0 0.27 10.5 0.0 1.3 1 0 0 1 1 1 0 Thi4 family DNA_pol_A_exo1 PF01612.20 KXS15057.1 - 1.1e-47 162.0 0.1 1.7e-47 161.4 0.1 1.3 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.12 KXS15057.1 - 1e-13 51.8 0.0 4.3e-13 49.8 0.0 2.2 1 0 0 1 1 1 1 PMC2NT (NUC016) domain HRDC PF00570.23 KXS15057.1 - 1.9e-10 40.5 0.0 4e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 HRDC domain NST1 PF13945.6 KXS15057.1 - 0.13 12.3 3.2 0.28 11.3 3.2 1.5 1 0 0 1 1 1 0 Salt tolerance down-regulator Rnk_N PF14760.6 KXS15057.1 - 3.9 8.0 5.9 1.8 9.1 0.2 2.7 2 0 0 2 2 2 0 Rnk N-terminus Amidase PF01425.21 KXS15058.1 - 8.1e-116 387.6 0.3 1.1e-115 387.3 0.3 1.1 1 0 0 1 1 1 1 Amidase NAD_synthase PF02540.17 KXS15058.1 - 0.42 9.7 1.9 0.62 9.1 0.7 1.7 2 0 0 2 2 2 0 NAD synthase ECH_1 PF00378.20 KXS15060.1 - 1.2e-48 165.6 0.0 2.5e-48 164.6 0.0 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXS15060.1 - 4.4e-29 102.0 0.0 5.7e-29 101.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase SBD_N PF07005.11 KXS15061.1 - 3.8e-60 203.5 0.6 1.2e-59 201.9 0.2 2.0 2 0 0 2 2 2 1 Sugar-binding N-terminal domain NAD_binding_11 PF14833.6 KXS15061.1 - 4.9e-48 162.4 1.6 3.3e-33 114.5 0.1 2.8 3 0 0 3 3 3 2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NBD_C PF17042.5 KXS15061.1 - 1.5e-37 129.7 0.3 3.6e-37 128.5 0.3 1.7 1 0 0 1 1 1 1 Nucleotide-binding C-terminal domain NAD_binding_2 PF03446.15 KXS15061.1 - 4.4e-35 121.2 0.3 4.4e-35 121.2 0.3 2.1 3 0 0 3 3 3 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 KXS15061.1 - 0.013 15.4 0.1 0.027 14.4 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 KXS15061.1 - 0.019 15.5 0.0 0.097 13.3 0.0 2.3 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 KXS15061.1 - 0.04 13.3 0.0 0.14 11.5 0.0 1.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Tim17 PF02466.19 KXS15062.1 - 5.8e-08 33.1 1.6 0.0002 21.7 0.3 2.4 2 0 0 2 2 2 2 Tim17/Tim22/Tim23/Pmp24 family TMEM135_C_rich PF15982.5 KXS15062.1 - 0.0004 21.0 1.2 0.076 13.6 0.1 3.1 2 1 1 3 3 3 1 N-terminal cysteine-rich region of Transmembrane protein 135 RPE65 PF03055.15 KXS15063.1 - 1.3e-84 285.1 0.0 2e-84 284.4 0.0 1.2 1 1 0 1 1 1 1 Retinal pigment epithelial membrane protein FAM27 PF15832.5 KXS15064.1 - 0.019 15.5 10.1 0.019 15.5 10.1 10.8 2 2 5 7 7 7 0 FAM27 D and E protein family Forkhead_N PF08430.12 KXS15064.1 - 0.98 10.0 19.1 3.6 8.2 19.1 1.9 1 0 0 1 1 1 0 Forkhead N-terminal region DUF2663 PF10864.8 KXS15065.1 - 0.045 14.2 0.2 0.11 12.9 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2663) HIP1_clath_bdg PF16515.5 KXS15065.1 - 0.47 11.1 9.0 0.15 12.7 4.5 2.3 2 1 1 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Spc7 PF08317.11 KXS15065.1 - 1.7 7.4 9.6 2.2 7.1 9.6 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein U-box PF04564.15 KXS15067.1 - 1.4e-19 70.0 0.1 2.8e-19 69.1 0.1 1.5 1 0 0 1 1 1 1 U-box domain Vwaint PF14624.6 KXS15067.1 - 2.5e-17 62.8 0.1 4.9e-17 61.8 0.1 1.5 1 0 0 1 1 1 1 VWA / Hh protein intein-like Vint PF14623.6 KXS15067.1 - 1.6e-16 60.5 0.0 3.8e-16 59.3 0.0 1.6 1 0 0 1 1 1 1 Hint-domain VWA_2 PF13519.6 KXS15067.1 - 1.2e-15 58.0 0.1 2.5e-15 57.0 0.1 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 KXS15067.1 - 7.1e-15 55.7 0.0 1.2e-14 55.0 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 KXS15067.1 - 1.5e-06 28.3 0.0 1.9e-05 24.6 0.0 2.2 1 1 0 1 1 1 1 von Willebrand factor type A domain zf-Nse PF11789.8 KXS15067.1 - 0.0043 16.8 0.0 0.009 15.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Hint PF01079.20 KXS15067.1 - 0.0063 16.0 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 Hint module VWA_CoxE PF05762.14 KXS15067.1 - 0.064 12.6 0.0 0.8 9.1 0.0 2.5 3 0 0 3 3 3 0 VWA domain containing CoxE-like protein Abhydro_lipase PF04083.16 KXS15067.1 - 0.29 10.7 0.9 0.57 9.8 0.1 1.8 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region Zn_clus PF00172.18 KXS15068.1 - 0.0078 16.3 13.1 0.024 14.8 6.8 3.0 2 1 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain dbPDZ_assoc PF16610.5 KXS15069.1 - 0.18 12.0 1.4 0.41 10.9 0.1 2.1 3 0 0 3 3 3 0 Unstructured region between two PDZ domains on Dlg5 PAS PF00989.25 KXS15070.1 - 1.7e-06 28.0 0.0 2.9e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 PAS fold Zn_clus PF00172.18 KXS15070.1 - 0.00086 19.4 10.0 0.0018 18.3 10.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SelP_N PF04592.14 KXS15070.1 - 3 7.2 5.6 4.9 6.5 5.6 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Pkinase PF00069.25 KXS15071.1 - 3e-51 174.3 0.0 4.5e-51 173.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS15071.1 - 6.5e-21 74.8 0.0 1e-20 74.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXS15071.1 - 0.011 15.7 0.1 0.023 14.6 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family DEAD PF00270.29 KXS15072.1 - 5.5e-24 84.9 0.0 1.3e-23 83.6 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 KXS15072.1 - 2.7e-11 43.8 0.0 5.4e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KXS15072.1 - 1.4e-06 28.6 0.0 4.9e-05 23.7 0.0 2.4 1 1 0 1 1 1 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 KXS15072.1 - 0.003 17.3 0.0 0.0053 16.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain T2SSE PF00437.20 KXS15072.1 - 0.0071 15.4 0.0 0.015 14.3 0.0 1.5 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_19 PF13245.6 KXS15072.1 - 0.015 15.6 0.1 0.058 13.7 0.0 2.1 2 1 0 2 2 2 0 AAA domain UvrD-helicase PF00580.21 KXS15072.1 - 0.026 14.1 0.0 0.053 13.0 0.0 1.5 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain AAA_22 PF13401.6 KXS15072.1 - 0.086 13.1 0.1 1.1 9.5 0.1 2.4 1 1 0 1 1 1 0 AAA domain DUF4916 PF16262.5 KXS15072.1 - 0.14 11.7 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4916) HHH_5 PF14520.6 KXS15073.1 - 4e-07 30.5 0.1 7.6e-07 29.6 0.1 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_2 PF12826.7 KXS15073.1 - 0.023 14.8 0.0 0.092 12.9 0.0 1.9 1 1 0 1 1 1 0 Helix-hairpin-helix motif Cdd1 PF11731.8 KXS15073.1 - 0.099 12.9 0.0 0.28 11.4 0.0 1.8 1 0 0 1 1 1 0 Pathogenicity locus DNA_pol_lambd_f PF10391.9 KXS15073.1 - 0.1 12.5 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda AcetylCoA_hyd_C PF13336.6 KXS15075.1 - 1.9e-60 203.3 0.0 2.9e-60 202.7 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain AcetylCoA_hydro PF02550.15 KXS15075.1 - 1.8e-24 86.8 0.0 4e-24 85.7 0.0 1.5 1 1 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain FKBP_C PF00254.28 KXS15076.1 - 4.1e-30 104.0 0.0 7.2e-30 103.2 0.0 1.4 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase BTHB PF18410.1 KXS15076.1 - 1.2e-22 79.5 0.3 2.1e-22 78.7 0.3 1.4 1 0 0 1 1 1 1 Basic tilted helix bundle domain COX5A PF02284.16 KXS15077.1 - 2.9e-31 107.5 0.0 3.8e-31 107.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va PHINT_rpt PF14882.6 KXS15077.1 - 0.21 11.9 1.1 3.8 7.9 0.3 2.5 3 0 0 3 3 3 0 Phage-integrase repeat unit TPR_2 PF07719.17 KXS15078.1 - 0.05 13.7 0.4 0.05 13.7 0.4 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KXS15078.1 - 0.28 12.1 4.3 13 6.9 0.1 3.8 3 1 1 4 4 4 0 Tetratricopeptide repeat Iso_dh PF00180.20 KXS15080.1 - 1.3e-92 310.6 0.0 1.5e-92 310.4 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Ntox10 PF15520.6 KXS15080.1 - 0.013 15.4 0.3 0.027 14.4 0.3 1.4 1 0 0 1 1 1 0 Novel toxin 10 zf-PARP PF00645.18 KXS15081.1 - 2.5e-19 69.9 0.1 4.8e-19 69.0 0.1 1.5 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region CCDC53 PF10152.9 KXS15081.1 - 0.16 12.4 4.6 0.24 11.8 4.6 1.3 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex F-box-like PF12937.7 KXS15082.1 - 0.00069 19.5 0.0 0.0015 18.4 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXS15082.1 - 0.0071 16.2 0.0 0.016 15.0 0.0 1.6 1 0 0 1 1 1 1 F-box domain Dzip-like_N PF13815.6 KXS15083.1 - 1.9e-05 24.6 0.0 1.9e-05 24.6 0.0 9.6 8 2 0 10 10 10 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal KLRAQ PF10205.9 KXS15083.1 - 5.5e-05 23.3 3.8 5.5e-05 23.3 3.8 12.0 7 3 5 12 12 12 1 Predicted coiled-coil domain-containing protein HMMR_N PF15905.5 KXS15083.1 - 0.0052 16.3 9.9 0.0052 16.3 9.9 8.1 6 2 2 8 8 8 5 Hyaluronan mediated motility receptor N-terminal MUG113 PF13455.6 KXS15083.1 - 0.055 14.1 2.1 0.78 10.5 2.1 3.2 1 0 0 1 1 1 0 Meiotically up-regulated gene 113 HTH_11 PF08279.12 KXS15083.1 - 0.091 12.7 1.9 0.53 10.3 0.0 3.5 3 0 0 3 3 3 0 HTH domain DUF4250 PF14056.6 KXS15083.1 - 0.16 12.0 8.7 0.27 11.2 0.3 5.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4250) HAP1_N PF04849.13 KXS15084.1 - 0.00044 19.6 24.2 0.027 13.7 6.2 2.1 1 1 1 2 2 2 2 HAP1 N-terminal conserved region KASH_CCD PF14662.6 KXS15084.1 - 0.0035 17.2 28.9 0.32 10.8 1.9 2.6 1 1 0 2 2 2 2 Coiled-coil region of CCDC155 or KASH UDPG_MGDP_dh PF00984.19 KXS15084.1 - 0.012 15.8 0.0 0.022 14.9 0.0 1.5 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, central domain Herpes_BLRF2 PF05812.12 KXS15084.1 - 0.047 13.8 0.9 0.047 13.8 0.9 3.3 2 2 1 3 3 3 0 Herpesvirus BLRF2 protein TSC22 PF01166.18 KXS15084.1 - 0.14 12.5 0.7 0.14 12.5 0.7 4.0 5 0 0 5 5 5 0 TSC-22/dip/bun family FAA_hydro_N_2 PF18288.1 KXS15084.1 - 0.33 11.4 0.1 0.33 11.4 0.1 2.5 3 1 1 4 4 4 0 Fumarylacetoacetase N-terminal domain 2 ATG16 PF08614.11 KXS15084.1 - 0.38 10.9 32.5 0.097 12.9 12.0 2.5 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF4407 PF14362.6 KXS15084.1 - 0.41 10.0 13.4 0.38 10.0 12.4 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) HMMR_N PF15905.5 KXS15084.1 - 0.74 9.2 25.3 0.059 12.8 19.8 1.8 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Seryl_tRNA_N PF02403.22 KXS15084.1 - 1.4 9.1 19.1 0.23 11.7 10.8 2.6 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain YscO PF07321.12 KXS15084.1 - 2.9 7.9 32.2 0.046 13.7 12.5 2.9 2 1 1 3 3 3 0 Type III secretion protein YscO APG6_N PF17675.1 KXS15084.1 - 4.1 7.9 36.4 0.8 10.2 17.0 2.5 2 1 0 2 2 2 0 Apg6 coiled-coil region YabA PF06156.13 KXS15084.1 - 4.7 7.9 23.5 3.2 8.4 7.1 3.4 1 1 1 2 2 2 0 Initiation control protein YabA zf-MIZ PF02891.20 KXS15085.1 - 7.3e-06 25.6 0.0 1.3e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger PAS_4 PF08448.10 KXS15085.1 - 0.12 12.7 0.1 0.38 11.0 0.1 1.8 1 0 0 1 1 1 0 PAS fold cNMP_binding PF00027.29 KXS15086.1 - 1.9e-27 95.2 2.3 9.5e-07 28.8 0.0 5.6 5 1 0 5 5 5 4 Cyclic nucleotide-binding domain Patatin PF01734.22 KXS15086.1 - 8.2e-20 71.9 1.1 2.5e-12 47.4 0.3 2.7 2 0 0 2 2 2 2 Patatin-like phospholipase GST_N_4 PF17172.4 KXS15087.1 - 2.4e-15 57.1 0.0 4.9e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 KXS15087.1 - 4.4e-13 48.8 0.0 8.5e-13 47.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KXS15087.1 - 0.00032 20.7 0.0 0.00073 19.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KXS15087.1 - 0.0006 20.0 0.0 0.0012 19.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 KXS15087.1 - 0.016 15.5 0.0 0.03 14.6 0.0 1.5 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein GST_N_3 PF13417.6 KXS15087.1 - 0.072 13.5 0.0 0.33 11.4 0.0 2.1 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain ImpA_N PF06812.12 KXS15088.1 - 0.083 13.0 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 ImpA, N-terminal, type VI secretion system Lebercilin PF15619.6 KXS15089.1 - 7.9e-09 35.5 3.1 7.9e-09 35.5 3.1 2.3 2 0 0 2 2 2 1 Ciliary protein causing Leber congenital amaurosis disease WD40_alt PF14077.6 KXS15089.1 - 0.0027 17.5 0.3 0.0074 16.1 0.3 1.7 1 0 0 1 1 1 1 Alternative WD40 repeat motif TMF_TATA_bd PF12325.8 KXS15089.1 - 0.0094 16.2 3.8 0.0094 16.2 3.8 3.0 2 1 1 3 3 3 1 TATA element modulatory factor 1 TATA binding DMPK_coil PF08826.10 KXS15089.1 - 0.027 14.5 0.1 0.027 14.5 0.1 3.4 3 1 0 3 3 3 0 DMPK coiled coil domain like eIF3_subunit PF08597.10 KXS15089.1 - 0.046 13.6 8.9 0.081 12.8 2.6 2.2 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit TBD PF12845.7 KXS15089.1 - 0.075 12.9 0.2 0.17 11.8 0.2 1.6 1 0 0 1 1 1 0 TBD domain Cep57_CLD PF14073.6 KXS15089.1 - 0.086 12.9 9.3 0.066 13.2 2.2 2.5 2 0 0 2 2 2 0 Centrosome localisation domain of Cep57 Phlebovirus_NSM PF07246.11 KXS15089.1 - 0.19 11.1 1.2 4.7 6.5 0.1 2.1 2 0 0 2 2 2 0 Phlebovirus nonstructural protein NS-M GAS PF13851.6 KXS15089.1 - 0.23 10.8 10.9 0.42 9.9 1.3 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Prp19 PF08606.11 KXS15089.1 - 0.24 11.4 3.6 2.2 8.3 1.5 2.5 2 0 0 2 2 2 0 Prp19/Pso4-like Rootletin PF15035.6 KXS15089.1 - 1.2 9.1 11.9 0.27 11.2 1.7 2.2 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion DUF4140 PF13600.6 KXS15089.1 - 2.3 8.7 12.1 2.7 8.5 4.7 2.9 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) CENP-F_leu_zip PF10473.9 KXS15089.1 - 2.9 7.9 12.2 2.1 8.4 2.5 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DivIC PF04977.15 KXS15089.1 - 2.9 7.7 13.9 7.1 6.5 0.5 2.6 2 0 0 2 2 2 0 Septum formation initiator DUF4407 PF14362.6 KXS15089.1 - 4.9 6.4 17.1 6.2 6.1 4.4 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4407) Macoilin PF09726.9 KXS15089.1 - 5.4 5.5 10.6 1.4 7.4 3.2 2.1 2 0 0 2 2 2 0 Macoilin family APG6_N PF17675.1 KXS15089.1 - 6 7.4 20.1 9.3 6.8 6.8 2.3 1 1 0 2 2 2 0 Apg6 coiled-coil region LRR_8 PF13855.6 KXS15090.1 - 1.7e-12 46.9 4.9 2.3e-06 27.3 0.7 2.6 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KXS15090.1 - 1.6e-08 34.7 5.0 0.16 12.4 1.2 4.9 2 1 3 5 5 5 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KXS15090.1 - 7e-05 22.4 0.1 0.01 15.3 0.0 2.3 1 1 1 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.6 KXS15090.1 - 0.0032 17.4 2.4 13 6.1 0.1 4.3 4 0 0 4 4 4 2 Leucine Rich repeat G_glu_transpept PF01019.21 KXS15091.1 - 2e-176 587.7 0.0 2.3e-176 587.6 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase ELP6 PF09807.9 KXS15092.1 - 5.2e-21 75.2 0.1 8.3e-21 74.5 0.1 1.2 1 0 0 1 1 1 1 Elongation complex protein 6 Elong_Iki1 PF10483.9 KXS15092.1 - 0.0014 18.2 0.0 0.0036 16.9 0.0 1.6 1 1 0 1 1 1 1 Elongator subunit Iki1 zf-H2C2_2 PF13465.6 KXS15093.1 - 1.4e-14 53.7 14.1 1.6e-09 37.8 1.4 2.7 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 KXS15093.1 - 1.2e-05 25.5 19.0 0.0095 16.4 6.5 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXS15093.1 - 0.00046 20.8 18.1 0.0071 17.1 4.7 3.2 3 1 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KXS15093.1 - 0.0053 17.0 1.7 0.0057 16.9 1.7 1.1 1 0 0 1 1 1 1 C2H2-type zinc ribbon zf-CHY PF05495.12 KXS15093.1 - 0.0057 17.1 1.9 0.0071 16.8 1.9 1.3 1 0 0 1 1 1 1 CHY zinc finger zf_UBZ PF18439.1 KXS15093.1 - 0.016 14.7 1.8 0.32 10.6 0.1 2.3 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger HypA PF01155.19 KXS15093.1 - 0.018 15.1 1.0 0.043 13.8 0.3 1.7 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA XPA_N PF01286.18 KXS15093.1 - 0.026 14.6 3.0 0.68 10.0 0.4 2.2 2 0 0 2 2 2 0 XPA protein N-terminal zf-BED PF02892.15 KXS15093.1 - 0.027 14.5 8.2 0.69 10.0 0.6 2.9 1 1 2 3 3 3 0 BED zinc finger C1_1 PF00130.22 KXS15093.1 - 0.029 14.2 5.5 0.48 10.4 0.9 2.0 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Rep_fac-A_C PF08646.10 KXS15093.1 - 0.033 13.9 0.2 0.18 11.5 0.0 1.8 1 1 1 2 2 2 0 Replication factor-A C terminal domain zf-AN1 PF01428.16 KXS15093.1 - 0.033 14.3 10.0 1.1 9.5 2.9 2.4 1 1 1 2 2 2 0 AN1-like Zinc finger zf-C2HE PF16278.5 KXS15093.1 - 0.036 14.5 10.7 0.97 9.9 4.4 2.7 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-LYAR PF08790.11 KXS15093.1 - 0.044 13.7 5.6 1.7 8.6 0.1 2.5 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zinc-ribbons_6 PF07191.12 KXS15093.1 - 0.073 13.1 2.6 1 9.4 2.6 2.1 1 1 0 1 1 1 0 zinc-ribbons Zn-ribbon_8 PF09723.10 KXS15093.1 - 0.1 12.7 5.9 0.3 11.3 0.7 2.2 1 1 2 3 3 3 0 Zinc ribbon domain zf-C2H2_jaz PF12171.8 KXS15093.1 - 0.19 12.0 4.9 0.69 10.3 0.3 2.9 2 1 1 3 3 3 0 Zinc-finger double-stranded RNA-binding zinc_ribbon_4 PF13717.6 KXS15093.1 - 0.21 11.5 5.8 3.2 7.7 0.5 2.5 3 0 0 3 3 3 0 zinc-ribbon domain RIG-I_C-RD PF11648.8 KXS15093.1 - 0.41 10.9 3.0 1.2 9.4 0.2 2.0 1 1 1 2 2 2 0 C-terminal domain of RIG-I OrfB_Zn_ribbon PF07282.11 KXS15093.1 - 0.66 9.9 4.8 6.9 6.7 0.4 2.1 1 1 1 2 2 2 0 Putative transposase DNA-binding domain zf-C2H2_6 PF13912.6 KXS15093.1 - 0.88 9.6 16.3 0.26 11.3 2.9 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger HSD3 PF15244.6 KXS15094.1 - 0.44 10.0 1.8 0.75 9.2 1.8 1.3 1 0 0 1 1 1 0 Spermatogenesis-associated protein 7, or HSD3 ATP-synt_ab PF00006.25 KXS15095.1 - 1.4e-109 364.7 0.0 2e-109 364.2 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 KXS15095.1 - 5.7e-45 152.1 0.0 1.1e-44 151.2 0.0 1.5 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 KXS15095.1 - 4.3e-15 56.0 3.0 9.6e-15 54.9 3.0 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain SUZ PF12752.7 KXS15096.1 - 7.6e-11 42.6 5.7 7.6e-11 42.6 5.7 3.6 3 1 0 3 3 3 1 SUZ domain R3H PF01424.22 KXS15096.1 - 3.7e-06 26.8 0.1 7.1e-06 25.9 0.1 1.5 1 0 0 1 1 1 1 R3H domain DEAD PF00270.29 KXS15097.1 - 1.8e-43 148.3 1.0 2.5e-43 147.9 0.2 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXS15097.1 - 6.2e-32 110.2 0.2 2.1e-31 108.5 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXS15097.1 - 0.00011 22.3 0.1 0.00032 20.8 0.0 1.8 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KXS15097.1 - 0.00044 20.6 0.1 0.012 16.0 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KXS15097.1 - 0.0012 18.6 0.0 0.0027 17.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KXS15097.1 - 0.015 15.5 0.2 0.057 13.7 0.2 1.9 1 1 0 1 1 1 0 AAA domain Helicase_RecD PF05127.14 KXS15097.1 - 0.043 13.7 0.0 0.09 12.6 0.0 1.5 1 0 0 1 1 1 0 Helicase Flavi_DEAD PF07652.14 KXS15097.1 - 0.085 12.8 0.7 0.6 10.1 0.1 2.6 2 1 0 2 2 2 0 Flavivirus DEAD domain UvrD-helicase PF00580.21 KXS15097.1 - 0.13 11.8 0.6 0.18 11.3 0.1 1.5 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain DUF3449 PF11931.8 KXS15098.1 - 2.3e-74 249.2 0.4 2.3e-74 249.2 0.4 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF3449) SF3A3 PF16837.5 KXS15098.1 - 1.2e-23 83.4 0.1 3.9e-23 81.8 0.1 1.9 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 SF3a60_bindingd PF12108.8 KXS15098.1 - 2.1e-12 46.7 0.2 3.8e-12 45.9 0.2 1.5 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-met PF12874.7 KXS15098.1 - 1.4e-09 38.0 0.9 1.6e-06 28.3 0.3 2.4 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KXS15098.1 - 2.7e-06 27.5 0.2 2.7e-06 27.5 0.2 2.3 2 1 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KXS15098.1 - 0.016 15.5 0.3 0.17 12.3 0.0 2.4 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) PUF PF00806.19 KXS15099.1 - 4.7e-58 189.7 12.1 6.3e-07 28.7 0.4 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat zf-CCCH PF00642.24 KXS15099.1 - 3.9e-08 33.0 2.8 1.3e-07 31.3 2.8 1.9 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KXS15099.1 - 7.1e-07 29.1 6.4 2.4e-06 27.4 6.4 2.0 1 0 0 1 1 1 1 Zinc finger domain Torus PF16131.5 KXS15099.1 - 0.00026 21.7 0.1 0.00074 20.2 0.1 1.7 1 0 0 1 1 1 1 Torus domain zf-CCCH_4 PF18044.1 KXS15099.1 - 0.00029 20.6 4.0 0.00029 20.6 4.0 2.2 2 0 0 2 2 2 1 CCCH-type zinc finger zf-CCCH_2 PF14608.6 KXS15099.1 - 0.016 15.6 1.3 0.053 14.0 1.3 2.0 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger LOB PF03195.14 KXS15099.1 - 0.066 13.8 2.6 1.9 9.1 0.4 3.2 2 1 1 3 3 3 0 Lateral organ boundaries (LOB) domain Ribonucleas_3_3 PF14622.6 KXS15100.1 - 7.8e-21 74.6 0.0 1.2e-20 73.9 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 KXS15100.1 - 1.4e-09 38.5 0.0 3.4e-09 37.3 0.0 1.7 1 0 0 1 1 1 1 Ribonuclease III domain dsrm PF00035.26 KXS15100.1 - 6.7e-07 29.9 0.0 1.4e-06 28.9 0.0 1.6 1 0 0 1 1 1 1 Double-stranded RNA binding motif B56 PF01603.20 KXS15101.1 - 2e-195 649.6 9.3 2.4e-195 649.4 9.3 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Sec7_N PF12783.7 KXS15101.1 - 0.014 15.4 1.8 1 9.2 0.3 2.5 2 0 0 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal NAD1 PF18778.1 KXS15101.1 - 0.046 13.8 1.2 1 9.4 0.4 2.3 2 0 0 2 2 2 0 Novel AID APOBEC clade 1 Complex1_LYR PF05347.15 KXS15102.1 - 3.9e-13 49.2 0.1 3.9e-13 49.2 0.1 1.5 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KXS15102.1 - 0.016 15.9 0.0 0.02 15.6 0.0 1.2 1 0 0 1 1 1 0 Complex1_LYR-like Gcd10p PF04189.13 KXS15103.1 - 2.9e-64 217.1 0.0 4.8e-64 216.4 0.0 1.3 1 0 0 1 1 1 1 Gcd10p family Not1 PF04054.15 KXS15104.1 - 9.3e-140 465.7 1.9 2e-139 464.6 1.9 1.5 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 KXS15104.1 - 5.6e-94 313.7 0.9 1.9e-93 312.0 0.3 2.1 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain CNOT1_TTP_bind PF16417.5 KXS15104.1 - 1.9e-64 216.3 0.1 4.8e-64 215.0 0.1 1.7 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 TTP binding domain DUF3819 PF12842.7 KXS15104.1 - 5.2e-54 182.2 0.2 1.3e-53 180.8 0.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) CNOT1_HEAT PF16418.5 KXS15104.1 - 2e-39 135.1 0.0 8.3e-39 133.1 0.0 2.2 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 HEAT repeat G-patch_2 PF12656.7 KXS15105.1 - 8.7e-24 83.4 0.1 2.1e-23 82.2 0.1 1.7 1 0 0 1 1 1 1 G-patch domain G-patch PF01585.23 KXS15105.1 - 6e-05 22.9 0.2 0.0002 21.2 0.2 2.0 1 0 0 1 1 1 1 G-patch domain KOW PF00467.29 KXS15105.1 - 0.0077 16.2 2.1 0.0077 16.2 2.1 2.9 3 0 0 3 3 3 1 KOW motif HAS-barrel PF09378.10 KXS15105.1 - 0.022 14.9 0.2 0.059 13.5 0.2 1.7 1 0 0 1 1 1 0 HAS barrel domain 3-HAO PF06052.12 KXS15105.1 - 0.076 12.7 0.1 0.14 11.8 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyanthranilic acid dioxygenase KN17_SH3 PF18131.1 KXS15105.1 - 0.12 12.5 0.0 0.27 11.4 0.0 1.6 1 0 0 1 1 1 0 KN17 SH3-like C-terminal domain TAF6_C PF07571.13 KXS15106.1 - 6.7e-25 87.2 0.0 1.4e-24 86.2 0.0 1.6 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain TAF PF02969.17 KXS15106.1 - 2.5e-16 59.6 0.4 1.6e-15 57.0 0.1 2.2 2 0 0 2 2 2 1 TATA box binding protein associated factor (TAF) Histone PF00125.24 KXS15106.1 - 0.0027 18.0 0.1 0.0075 16.6 0.0 1.8 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 SPT16 PF08644.11 KXS15107.1 - 3.3e-53 179.9 0.0 3.3e-53 179.9 0.0 2.3 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.6 KXS15107.1 - 1.8e-39 135.1 0.2 5e-39 133.7 0.2 1.8 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.24 KXS15107.1 - 2.2e-26 92.9 0.0 3.2e-26 92.3 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 KXS15107.1 - 7.1e-11 42.4 0.1 2.1e-10 40.9 0.1 1.8 1 0 0 1 1 1 1 Histone chaperone Rttp106-like DUF1623 PF07785.11 KXS15107.1 - 0.047 13.9 0.1 0.18 12.0 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1623) DUF4820 PF16091.5 KXS15107.1 - 4.6 6.5 7.5 0.36 10.2 1.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) DUF908 PF06012.12 KXS15107.1 - 5 6.4 5.2 8.5 5.7 0.2 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF908) UCH PF00443.29 KXS15108.1 - 5.6e-42 144.0 0.0 3.4e-41 141.5 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KXS15108.1 - 3.4e-05 23.6 0.0 0.00011 21.9 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase LSM PF01423.22 KXS15109.1 - 4.3e-17 61.6 0.0 5.7e-17 61.2 0.0 1.2 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 KXS15109.1 - 0.0076 15.9 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 Hfq protein PhnA PF03831.14 KXS15109.1 - 0.094 12.6 0.2 17 5.4 0.0 2.4 1 1 0 2 2 2 0 PhnA domain RB_B PF01857.20 KXS15110.1 - 4.3e-15 55.9 0.8 3.9e-14 52.8 0.7 2.5 2 1 0 2 2 2 1 Retinoblastoma-associated protein B domain RB_A PF01858.17 KXS15110.1 - 2.5e-06 27.5 0.1 9.2e-06 25.6 0.0 1.8 1 1 1 2 2 2 1 Retinoblastoma-associated protein A domain DUF4478 PF14793.6 KXS15111.1 - 0.14 12.1 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Pyrimidine/purine nucleotide 5'-monophosphate nucleosidases PTE PF02126.18 KXS15111.1 - 0.15 11.4 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotriesterase family COX4 PF02936.14 KXS15112.1 - 5.4e-11 42.7 0.0 6.6e-11 42.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV Acetyltransf_1 PF00583.25 KXS15113.1 - 1.2e-12 48.1 0.0 1.7e-12 47.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXS15113.1 - 1.4e-09 37.9 0.2 2e-09 37.5 0.2 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXS15113.1 - 2.7e-06 27.2 0.1 4.1e-06 26.7 0.1 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 KXS15113.1 - 3.4e-06 27.4 0.1 5.3e-06 26.8 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KXS15113.1 - 0.011 15.8 0.4 0.033 14.3 0.3 1.7 1 1 1 2 2 2 0 Acetyltransferase (GNAT) domain M16C_assoc PF08367.11 KXS15113.1 - 0.052 12.7 0.0 0.076 12.1 0.0 1.3 1 0 0 1 1 1 0 Peptidase M16C associated DUF5126 PF17166.4 KXS15113.1 - 0.13 12.2 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5126) HAUS4 PF14735.6 KXS15114.1 - 1.1e-23 84.2 0.1 1.9e-23 83.4 0.1 1.3 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 4 PTPlike_phytase PF14566.6 KXS15115.1 - 8.5e-127 419.0 0.0 3.1e-41 141.1 0.0 3.3 3 0 0 3 3 3 3 Inositol hexakisphosphate DSPc PF00782.20 KXS15115.1 - 6e-06 26.1 0.0 0.34 10.7 0.0 3.6 3 0 0 3 3 3 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KXS15115.1 - 0.00047 19.8 0.0 2.8 7.4 0.0 3.2 3 0 0 3 3 3 3 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 KXS15115.1 - 0.0048 16.9 0.0 3.8 7.4 0.0 3.3 3 0 0 3 3 3 1 Tyrosine phosphatase family FA_desaturase PF00487.24 KXS15116.1 - 2.1e-35 122.8 16.3 2.2e-34 119.4 14.3 2.1 2 0 0 2 2 2 2 Fatty acid desaturase Cyt-b5 PF00173.28 KXS15116.1 - 6e-24 84.0 0.0 1.4e-23 82.8 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Clat_adaptor_s PF01217.20 KXS15117.1 - 4.2e-27 94.8 0.5 4.8e-27 94.6 0.5 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DRIM PF07539.12 KXS15117.1 - 0.063 11.6 0.0 0.075 11.3 0.0 1.0 1 0 0 1 1 1 0 Down-regulated in metastasis CN_hydrolase PF00795.22 KXS15118.1 - 1.6e-37 129.3 0.0 2.6e-37 128.6 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 KXS15118.1 - 1.1e-26 93.4 0.0 1.1e-25 90.2 0.0 2.1 1 1 0 1 1 1 1 NAD synthase Asn_synthase PF00733.21 KXS15118.1 - 0.094 12.4 0.1 0.16 11.6 0.1 1.3 1 0 0 1 1 1 0 Asparagine synthase DUF5395 PF17373.2 KXS15118.1 - 0.2 12.3 0.2 59 4.4 0.0 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF5395) zf-CCHC PF00098.23 KXS15119.1 - 1.5e-22 78.6 32.3 4e-08 33.0 2.2 4.5 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_3 PF13917.6 KXS15119.1 - 1.1e-05 25.3 17.1 0.011 15.7 0.2 4.2 3 1 1 4 4 4 3 Zinc knuckle zf-CCHC_5 PF14787.6 KXS15119.1 - 0.002 17.8 0.8 0.002 17.8 0.8 4.1 4 0 0 4 4 4 2 GAG-polyprotein viral zinc-finger zf-CCHC_4 PF14392.6 KXS15119.1 - 0.061 13.1 0.7 0.061 13.1 0.7 4.0 4 0 0 4 4 4 0 Zinc knuckle DZR PF12773.7 KXS15119.1 - 0.93 9.6 15.9 8.9 6.4 0.0 3.3 2 1 0 3 3 3 0 Double zinc ribbon zf-CCHC_6 PF15288.6 KXS15119.1 - 9.8 6.1 18.8 0.36 10.7 0.7 4.1 3 1 1 4 4 4 0 Zinc knuckle UPF0203 PF05254.12 KXS15120.1 - 0.092 13.0 1.1 0.41 10.9 1.1 1.8 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) DAD PF02109.16 KXS15121.1 - 5.2e-42 142.6 0.9 6.5e-42 142.3 0.9 1.1 1 0 0 1 1 1 1 DAD family zf-met2 PF12907.7 KXS15122.1 - 2.4e-14 53.1 4.5 3.7e-14 52.6 4.5 1.3 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.14 KXS15122.1 - 4.6e-07 30.6 12.1 1.2e-05 26.0 9.0 2.1 2 0 0 2 2 2 2 4F5 protein family zf-C2H2_12 PF18658.1 KXS15122.1 - 0.064 12.8 0.3 0.09 12.4 0.3 1.2 1 0 0 1 1 1 0 Zinc-finger C2H2-type Strabismus PF06638.11 KXS15122.1 - 0.15 10.7 0.2 0.17 10.5 0.2 1.0 1 0 0 1 1 1 0 Strabismus protein Ribosomal_L14 PF00238.19 KXS15123.1 - 5.4e-37 126.6 0.1 6.5e-37 126.3 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Cpn60_TCP1 PF00118.24 KXS15124.1 - 4.5e-155 517.0 13.4 5e-155 516.9 13.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family HTH_26 PF13443.6 KXS15124.1 - 0.075 13.5 0.1 0.26 11.8 0.1 1.9 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain Annexin PF00191.20 KXS15125.1 - 6.1e-29 99.9 0.1 3.9e-14 52.5 0.0 4.1 4 0 0 4 4 4 3 Annexin MSA_2 PF00985.17 KXS15125.1 - 0.11 12.8 0.1 0.24 11.8 0.1 1.4 1 0 0 1 1 1 0 Merozoite Surface Antigen 2 (MSA-2) family ADH_zinc_N PF00107.26 KXS15126.1 - 1.1e-24 86.9 0.4 2e-24 86.0 0.4 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXS15126.1 - 5.9e-12 45.4 0.7 4.6e-11 42.6 0.0 2.3 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KXS15126.1 - 3.2e-05 25.0 0.0 6.1e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 KXS15126.1 - 0.69 9.3 3.3 2.1 7.7 2.3 2.1 2 1 0 2 2 2 0 short chain dehydrogenase Ribosomal_S6e PF01092.19 KXS15127.1 - 1.7e-57 192.8 0.9 2.1e-57 192.5 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein S6e DUF4574 PF15141.6 KXS15127.1 - 0.43 10.5 4.2 0.78 9.7 4.2 1.4 1 0 0 1 1 1 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 Cullin PF00888.22 KXS15129.1 - 6.6e-193 642.7 0.0 8e-193 642.4 0.0 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KXS15129.1 - 2.6e-27 94.6 0.2 6.4e-27 93.4 0.2 1.7 1 0 0 1 1 1 1 Cullin protein neddylation domain Stork_head PF10264.9 KXS15129.1 - 0.11 12.7 0.1 4.5 7.5 0.1 2.6 2 0 0 2 2 2 0 Winged helix Storkhead-box1 domain Actin PF00022.19 KXS15130.1 - 2.6e-86 289.8 0.0 1.5e-84 284.0 0.0 2.0 1 1 0 1 1 1 1 Actin FtsA PF14450.6 KXS15130.1 - 0.00019 21.8 0.1 0.12 12.8 0.0 3.1 2 1 0 2 2 2 1 Cell division protein FtsA MreB_Mbl PF06723.13 KXS15130.1 - 0.0002 20.3 0.0 0.00064 18.6 0.0 1.8 1 1 0 1 1 1 1 MreB/Mbl protein PEN-2 PF10251.9 KXS15131.1 - 4.3e-27 94.4 0.7 4.8e-27 94.2 0.7 1.0 1 0 0 1 1 1 1 Presenilin enhancer-2 subunit of gamma secretase DUF2070 PF09843.9 KXS15131.1 - 0.014 13.7 0.2 0.015 13.6 0.2 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Bcr-Abl_Oligo PF09036.10 KXS15132.1 - 2 8.5 15.8 0.16 12.0 1.5 3.5 2 1 1 3 3 3 0 Bcr-Abl oncoprotein oligomerisation domain KxDL PF10241.9 KXS15132.1 - 9.6 6.6 15.0 7.9 6.8 5.2 3.4 3 1 1 4 4 4 0 Uncharacterized conserved protein zf-C2H2 PF00096.26 KXS15133.1 - 8e-05 22.9 10.9 0.00021 21.6 1.2 3.6 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KXS15133.1 - 0.00031 21.0 9.6 0.0015 18.9 0.4 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KXS15133.1 - 0.004 17.9 10.8 0.0072 17.1 0.8 3.9 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KXS15133.1 - 0.0085 16.1 0.4 0.0085 16.1 0.4 2.4 2 0 0 2 2 2 1 C2H2-type zinc finger C1_4 PF07975.12 KXS15133.1 - 0.051 13.8 1.6 0.13 12.5 1.0 2.0 1 1 0 1 1 1 0 TFIIH C1-like domain zf-C2H2_jaz PF12171.8 KXS15133.1 - 0.062 13.6 0.1 0.062 13.6 0.1 2.1 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Zn_Tnp_IS1595 PF12760.7 KXS15133.1 - 0.34 10.9 2.1 3.5 7.7 0.5 2.3 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf-BED PF02892.15 KXS15133.1 - 0.53 10.3 2.6 0.86 9.7 0.1 2.4 3 0 0 3 3 3 0 BED zinc finger WD40 PF00400.32 KXS15134.1 - 4.8e-28 96.8 5.7 1.5e-07 32.0 0.0 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat Katanin_con80 PF13925.6 KXS15134.1 - 1.3e-26 93.5 0.0 2.6e-26 92.6 0.0 1.5 1 0 0 1 1 1 1 con80 domain of Katanin ANAPC4_WD40 PF12894.7 KXS15134.1 - 1.2e-09 38.3 0.0 0.0078 16.5 0.0 4.7 1 1 4 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain SF3b1 PF08920.10 KXS15135.1 - 1e-45 155.0 19.8 6.8e-43 145.9 5.0 4.5 2 1 1 3 3 3 2 Splicing factor 3B subunit 1 HEAT_2 PF13646.6 KXS15135.1 - 2.5e-11 43.8 8.0 0.0094 16.3 0.1 8.1 6 2 1 8 8 8 3 HEAT repeats HEAT_EZ PF13513.6 KXS15135.1 - 1.1e-10 41.8 4.1 0.59 10.7 0.0 7.6 7 1 0 7 7 7 3 HEAT-like repeat HEAT PF02985.22 KXS15135.1 - 3.6e-10 39.2 7.3 2.5 8.6 0.0 8.7 9 0 0 9 9 9 3 HEAT repeat Cnd1 PF12717.7 KXS15135.1 - 1.2e-05 25.4 9.4 0.7 9.9 0.0 6.3 7 1 1 8 8 8 3 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 KXS15135.1 - 0.00013 22.5 3.6 5.6 7.6 0.0 5.1 5 0 0 5 5 4 2 Vacuolar 14 Fab1-binding region DUF3385 PF11865.8 KXS15135.1 - 0.00039 20.4 4.1 0.27 11.1 0.2 4.8 5 0 0 5 5 5 1 Domain of unknown function (DUF3385) CLASP_N PF12348.8 KXS15135.1 - 0.00042 20.0 0.8 1.4 8.5 0.0 3.4 3 0 0 3 3 3 2 CLASP N terminal Dopey_N PF04118.14 KXS15135.1 - 0.0023 17.1 0.9 0.33 10.0 0.0 3.7 2 1 1 4 4 4 1 Dopey, N-terminal DNA_pol_phi PF04931.13 KXS15135.1 - 0.015 13.5 0.0 1.9 6.5 0.0 2.3 2 0 0 2 2 2 0 DNA polymerase phi Adaptin_N PF01602.20 KXS15135.1 - 0.015 13.9 3.1 0.18 10.3 0.1 2.9 2 1 0 2 2 2 0 Adaptin N terminal region NUC173 PF08161.12 KXS15135.1 - 0.034 13.8 3.7 0.93 9.1 0.0 4.5 6 0 0 6 6 6 0 NUC173 domain MMS19_C PF12460.8 KXS15135.1 - 0.077 12.1 0.0 4.3 6.3 0.0 3.4 3 1 1 4 4 4 0 RNAPII transcription regulator C-terminal Arm PF00514.23 KXS15135.1 - 0.33 11.1 2.4 38 4.5 0.0 4.6 6 0 0 6 6 5 0 Armadillo/beta-catenin-like repeat TPR_19 PF14559.6 KXS15136.1 - 7e-14 52.1 8.9 0.0027 18.2 0.4 6.4 5 2 1 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 KXS15136.1 - 1.5e-10 41.2 11.4 0.42 10.9 0.0 8.1 8 2 0 8 8 7 3 Tetratricopeptide repeat TPR_2 PF07719.17 KXS15136.1 - 8.7e-09 34.8 20.9 0.099 12.8 0.1 9.2 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_14 PF13428.6 KXS15136.1 - 6.9e-07 29.6 12.8 3.4 8.7 0.1 8.4 6 3 3 9 9 8 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KXS15136.1 - 7.5e-07 29.3 16.8 0.0011 19.2 4.2 5.0 5 2 0 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 KXS15136.1 - 8.1e-07 29.6 15.3 0.017 15.7 0.3 6.4 6 1 0 7 7 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 KXS15136.1 - 3.8e-06 26.6 9.7 3.1 8.0 0.0 7.1 8 1 0 8 8 6 2 Tetratricopeptide repeat TPR_15 PF13429.6 KXS15136.1 - 0.00081 18.7 6.1 0.61 9.3 0.7 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KXS15136.1 - 0.0024 17.6 16.6 12 5.9 0.1 7.8 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_6 PF13174.6 KXS15136.1 - 0.0032 18.0 9.8 0.23 12.2 0.1 6.5 7 0 0 7 7 7 1 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 KXS15136.1 - 0.0058 16.3 0.9 0.24 11.0 0.0 3.6 5 0 0 5 5 4 1 Bacterial type III secretion protein (HrpB1_HrpK) TPR_8 PF13181.6 KXS15136.1 - 0.018 15.2 13.1 5.9 7.4 0.0 6.4 8 0 0 8 8 6 0 Tetratricopeptide repeat DUF919 PF06034.11 KXS15136.1 - 0.028 14.3 0.6 0.074 12.9 0.6 1.7 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF919) DUF285 PF03382.14 KXS15136.1 - 0.064 13.0 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Mycoplasma protein of unknown function, DUF285 DUF3808 PF10300.9 KXS15136.1 - 0.083 11.6 3.6 0.053 12.3 1.0 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3808) Sec16_C PF12931.7 KXS15136.1 - 0.093 12.4 0.7 0.2 11.3 0.7 1.5 1 0 0 1 1 1 0 Sec23-binding domain of Sec16 PPR_2 PF13041.6 KXS15136.1 - 0.11 12.7 0.0 59 4.0 0.0 4.3 4 0 0 4 4 4 0 PPR repeat family TPR_17 PF13431.6 KXS15136.1 - 0.35 11.3 4.6 39 4.9 0.1 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_9 PF13371.6 KXS15136.1 - 0.39 10.9 5.8 8.2 6.7 0.2 4.0 5 0 0 5 5 4 0 Tetratricopeptide repeat SNAP PF14938.6 KXS15136.1 - 0.45 9.9 11.8 1.2 8.5 0.1 3.8 3 1 1 4 4 4 0 Soluble NSF attachment protein, SNAP TPR_10 PF13374.6 KXS15136.1 - 0.96 9.4 5.6 20 5.2 0.1 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat ANAPC5 PF12862.7 KXS15136.1 - 6.1 7.0 8.4 1.7 8.8 0.1 4.1 6 0 0 6 6 5 0 Anaphase-promoting complex subunit 5 Bromodomain PF00439.25 KXS15137.1 - 3.1e-118 386.1 4.9 9.2e-21 73.7 0.0 7.1 7 0 0 7 7 7 6 Bromodomain Peptidase_M1 PF01433.20 KXS15137.1 - 6.8e-12 45.4 0.0 2e-11 43.9 0.0 1.8 1 1 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 KXS15137.1 - 1.2e-05 25.5 0.0 0.003 17.8 0.0 2.4 2 0 0 2 2 2 2 Peptidase M1 N-terminal domain UQ_con PF00179.26 KXS15138.1 - 8.6e-18 64.3 0.0 1.5e-17 63.5 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme UQ_con PF00179.26 KXS15141.1 - 1e-47 161.3 0.0 1.2e-47 161.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KXS15141.1 - 0.0082 15.8 0.0 0.01 15.5 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KXS15141.1 - 0.019 15.2 0.0 0.022 15.0 0.0 1.3 1 0 0 1 1 1 0 RWD domain Raffinose_syn PF05691.12 KXS15143.1 - 5.6e-20 70.7 2.8 2.4e-08 32.3 0.1 4.6 2 1 1 3 3 3 3 Raffinose synthase or seed imbibition protein Sip1 Melibiase PF02065.18 KXS15143.1 - 0.026 13.5 0.0 0.043 12.8 0.0 1.3 1 1 0 1 1 1 0 Melibiase Macoilin PF09726.9 KXS15144.1 - 0.069 11.7 20.9 0.093 11.3 20.9 1.3 1 0 0 1 1 1 0 Macoilin family Kinesin PF00225.23 KXS15145.1 - 1.4e-99 333.2 0.2 2.1e-99 332.6 0.2 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KXS15145.1 - 7e-23 81.2 0.0 5.3e-22 78.4 0.0 2.2 2 0 0 2 2 2 1 Microtubule binding AAA_30 PF13604.6 KXS15145.1 - 0.0038 17.0 0.1 0.0084 15.8 0.1 1.5 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 KXS15145.1 - 0.035 14.1 0.2 0.13 12.2 0.0 2.1 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KXS15145.1 - 0.22 11.8 1.0 1.1 9.6 0.1 2.5 2 1 0 2 2 2 0 AAA domain PEHE PF15275.6 KXS15146.1 - 4.6e-05 24.1 5.6 4.6e-05 24.1 5.6 3.3 2 1 1 3 3 3 1 PEHE domain SAS4 PF15460.6 KXS15146.1 - 0.0017 18.4 4.5 0.0043 17.1 4.5 1.6 1 0 0 1 1 1 1 Something about silencing, SAS, complex subunit 4 Pkinase PF00069.25 KXS15147.1 - 2e-70 237.2 0.0 2.7e-70 236.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS15147.1 - 9.1e-38 130.0 0.0 1.4e-37 129.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 KXS15147.1 - 1.1e-30 105.6 0.1 5.8e-17 61.6 0.1 2.6 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.6 KXS15147.1 - 6.3e-06 25.7 0.0 2.8e-05 23.6 0.0 1.9 1 1 0 2 2 2 1 Kinase-like DUF365 PF04033.12 KXS15147.1 - 0.064 13.5 1.2 0.11 12.8 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF365) SPATIAL PF15256.6 KXS15147.1 - 0.1 12.9 0.6 0.23 11.8 0.6 1.5 1 0 0 1 1 1 0 SPATIAL APH PF01636.23 KXS15147.1 - 0.19 11.6 0.9 6.2 6.7 0.1 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family Topoisom_I PF01028.20 KXS15148.1 - 9.7e-100 332.6 2.4 2.5e-99 331.2 2.4 1.7 1 0 0 1 1 1 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.15 KXS15148.1 - 5.2e-94 313.7 1.0 5.2e-94 313.7 1.0 3.3 3 1 0 3 3 3 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topo_C_assoc PF14370.6 KXS15148.1 - 2.8e-34 116.9 1.2 1e-33 115.1 1.2 2.1 1 0 0 1 1 1 1 C-terminal topoisomerase domain Brix PF04427.18 KXS15149.1 - 2.8e-39 135.2 0.1 3.5e-39 134.9 0.1 1.1 1 0 0 1 1 1 1 Brix domain tRNA-synt_2c PF01411.19 KXS15150.1 - 1.5e-221 736.7 0.0 3.4e-221 735.6 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 KXS15150.1 - 7.9e-16 57.9 0.1 1.8e-15 56.7 0.1 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 KXS15150.1 - 6.2e-14 52.6 5.8 6.2e-14 52.6 5.8 1.8 2 0 0 2 2 2 1 DHHA1 domain PWWP PF00855.17 KXS15151.1 - 4.6e-16 59.0 1.0 4.6e-16 59.0 1.0 2.9 2 1 0 2 2 2 1 PWWP domain Med26 PF08711.11 KXS15151.1 - 5e-05 23.2 1.0 5e-05 23.2 1.0 2.4 2 1 1 3 3 3 1 TFIIS helical bundle-like domain Smg8_Smg9 PF10220.9 KXS15151.1 - 0.39 9.0 10.9 0.52 8.5 10.9 1.1 1 0 0 1 1 1 0 Smg8_Smg9 Presenilin PF01080.17 KXS15151.1 - 0.55 8.9 20.5 0.84 8.3 20.5 1.3 1 0 0 1 1 1 0 Presenilin SLC12 PF03522.15 KXS15151.1 - 5.1 6.0 16.3 7.2 5.5 16.3 1.3 1 0 0 1 1 1 0 Solute carrier family 12 DNA_pol_phi PF04931.13 KXS15151.1 - 5.9 4.9 30.1 8.4 4.3 30.1 1.3 1 0 0 1 1 1 0 DNA polymerase phi IF-2B PF01008.17 KXS15152.1 - 2.4e-38 131.9 1.8 2.1e-36 125.6 1.8 2.0 1 1 0 1 1 1 1 Initiation factor 2 subunit family Ribosomal_S16 PF00886.19 KXS15152.1 - 0.09 12.9 0.0 1.1 9.4 0.0 2.2 2 0 0 2 2 2 0 Ribosomal protein S16 DUF3844 PF12955.7 KXS15153.1 - 9.7e-16 57.8 3.3 1.7e-15 57.0 3.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) Actin PF00022.19 KXS15154.1 - 3.7e-151 503.4 0.0 1.2e-150 501.7 0.0 1.6 1 1 0 1 1 1 1 Actin GerD PF17898.1 KXS15154.1 - 0.055 13.4 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 Spore germination GerD central core domain zf-HC5HC2H_2 PF13832.6 KXS15155.1 - 1.1e-22 80.2 8.9 1.1e-22 80.2 8.9 4.2 4 1 0 4 4 4 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 KXS15155.1 - 9.3e-17 61.1 7.2 9.3e-17 61.1 7.2 4.8 4 1 1 5 5 5 2 PHD-like zinc-binding domain BAH PF01426.18 KXS15155.1 - 1.3e-14 54.1 0.1 2.7e-14 53.1 0.1 1.5 1 0 0 1 1 1 1 BAH domain PHD PF00628.29 KXS15155.1 - 9.3e-13 47.9 21.8 7.9e-08 32.1 5.6 5.4 6 0 0 6 6 6 3 PHD-finger PHD_2 PF13831.6 KXS15155.1 - 1.1e-10 40.9 5.8 1.1e-10 40.9 5.8 5.5 6 0 0 6 6 6 1 PHD-finger Zn_ribbon_17 PF17120.5 KXS15155.1 - 0.0039 16.8 5.4 0.0039 16.8 5.4 5.1 6 0 0 6 6 6 1 Zinc-ribbon, C4HC2 type ELM2 PF01448.24 KXS15155.1 - 0.0067 17.2 0.0 0.024 15.4 0.0 2.0 1 0 0 1 1 1 1 ELM2 domain zf-rbx1 PF12678.7 KXS15155.1 - 6.1 7.2 28.0 0.09 13.1 1.0 4.3 3 0 0 3 3 3 0 RING-H2 zinc finger domain HMA PF00403.26 KXS15156.1 - 1.4e-44 150.3 1.3 3.5e-14 53.0 0.1 4.6 5 0 0 5 5 5 3 Heavy-metal-associated domain E1-E2_ATPase PF00122.20 KXS15156.1 - 1e-41 142.4 2.4 1e-41 142.4 2.4 2.7 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 KXS15156.1 - 8.5e-35 120.9 0.2 1.9e-34 119.8 0.2 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KXS15156.1 - 0.0011 18.8 1.1 0.0028 17.5 0.4 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 KXS15156.1 - 0.068 13.3 0.0 0.89 9.7 0.0 2.9 3 0 0 3 3 3 0 Haloacid dehalogenase-like hydrolase FXa_inhibition PF14670.6 KXS15156.1 - 7.2 7.0 8.9 11 6.4 0.4 3.2 3 0 0 3 3 3 0 Coagulation Factor Xa inhibitory site DUF1899 PF08953.11 KXS15157.1 - 2.5e-26 91.3 0.1 5.4e-26 90.3 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 KXS15157.1 - 9.3e-21 73.5 0.2 1.8e-20 72.5 0.2 1.5 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 KXS15157.1 - 3e-12 46.9 8.9 0.0023 18.7 0.3 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXS15157.1 - 0.00018 21.8 0.3 0.0017 18.6 0.2 2.5 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain PRKG1_interact PF15898.5 KXS15157.1 - 0.0081 17.0 4.1 0.014 16.3 4.1 1.4 1 0 0 1 1 1 1 cGMP-dependent protein kinase interacting domain SYF2 PF08231.12 KXS15158.1 - 2.6e-47 161.2 9.0 2.6e-47 161.2 9.0 2.1 2 0 0 2 2 2 1 SYF2 splicing factor MCRA PF06100.11 KXS15159.1 - 2.2e-178 594.1 0.0 2.5e-178 593.9 0.0 1.0 1 0 0 1 1 1 1 MCRA family DAO PF01266.24 KXS15159.1 - 0.00044 19.9 0.4 0.0061 16.2 0.4 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXS15159.1 - 0.0011 19.1 0.6 0.0029 17.8 0.6 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Exo_endo_phos PF03372.23 KXS15160.1 - 2.6e-06 27.1 0.0 1.4e-05 24.8 0.0 2.0 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family WD40 PF00400.32 KXS15161.1 - 5e-36 122.1 19.6 2.3e-06 28.2 0.7 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXS15161.1 - 1.9e-17 63.3 1.6 0.00059 20.1 0.1 6.0 2 1 4 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KXS15161.1 - 2.5e-10 40.6 0.7 0.015 15.1 0.0 3.1 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KXS15161.1 - 8.7e-06 24.9 0.2 0.055 12.4 0.4 3.4 1 1 3 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KXS15161.1 - 0.0032 16.8 0.0 0.053 12.8 0.0 2.0 2 0 0 2 2 2 1 WD40-like domain RhoGAP PF00620.27 KXS15164.1 - 1.1e-39 135.7 0.0 1.7e-39 135.1 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain RhoGAP PF00620.27 KXS15165.1 - 1.9e-32 112.2 0.5 3.6e-32 111.3 0.1 1.7 2 0 0 2 2 2 1 RhoGAP domain RhoGEF PF00621.20 KXS15165.1 - 1.7e-20 74.0 0.0 2.7e-20 73.3 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.21 KXS15165.1 - 6.9e-09 35.6 0.0 1.5e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) SPT6_acidic PF14632.6 KXS15165.1 - 0.087 13.4 0.0 0.24 12.0 0.0 1.7 1 0 0 1 1 1 0 Acidic N-terminal SPT6 RhoGEF PF00621.20 KXS15166.1 - 8.8e-16 58.7 0.0 1.2e-15 58.2 0.0 1.2 1 0 0 1 1 1 1 RhoGEF domain Nup35_RRM PF05172.13 KXS15167.1 - 7.3e-08 32.3 0.0 1.4e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.6 KXS15167.1 - 0.0022 18.0 0.0 0.0034 17.4 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif CTP_synth_N PF06418.14 KXS15168.1 - 1.1e-121 405.2 0.1 1.5e-121 404.8 0.1 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 KXS15168.1 - 3.1e-51 173.9 0.0 4.9e-51 173.2 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KXS15168.1 - 1e-06 28.7 0.0 2.6e-06 27.3 0.0 1.7 1 1 0 1 1 1 1 Peptidase C26 CbiA PF01656.23 KXS15168.1 - 0.0016 18.5 0.0 0.01 15.9 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MeaB PF03308.16 KXS15168.1 - 0.054 12.5 0.2 0.086 11.8 0.2 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Clathrin_lg_ch PF01086.17 KXS15169.1 - 2.6e-35 122.5 0.4 5.4e-35 121.5 0.4 1.5 1 1 0 1 1 1 1 Clathrin light chain Rib_5-P_isom_A PF06026.14 KXS15170.1 - 1.8e-60 203.5 0.0 2.3e-60 203.1 0.0 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) Mg_trans_NIPA PF05653.14 KXS15171.1 - 1.1e-26 93.7 19.3 4.5e-15 55.5 5.6 2.6 3 0 0 3 3 3 2 Magnesium transporter NIPA EamA PF00892.20 KXS15171.1 - 4.4e-08 33.4 3.7 4.4e-08 33.4 3.7 3.2 4 0 0 4 4 4 1 EamA-like transporter family TMEM234 PF10639.9 KXS15171.1 - 1.2e-06 28.5 0.6 3.6e-06 27.0 0.1 2.0 2 0 0 2 2 2 1 Putative transmembrane family 234 UAA PF08449.11 KXS15171.1 - 0.00056 19.2 0.8 0.00056 19.2 0.8 1.6 2 0 0 2 2 2 1 UAA transporter family Nodulin_late PF07127.11 KXS15171.1 - 1.6 9.2 6.6 8.8 6.8 0.0 3.7 4 0 0 4 4 4 0 Late nodulin protein RNA_pol_Rbc25 PF08292.12 KXS15172.1 - 6.9e-18 65.1 0.0 3.7e-17 62.8 0.0 1.9 1 1 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 KXS15172.1 - 1.6e-14 54.0 0.5 3.2e-14 53.1 0.1 1.7 2 0 0 2 2 2 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 T2SSB PF16537.5 KXS15173.1 - 0.16 11.6 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Type II secretion system protein B PAM2 PF07145.15 KXS15174.1 - 0.021 14.5 0.3 0.047 13.4 0.3 1.6 1 0 0 1 1 1 0 Ataxin-2 C-terminal region Pkinase_Tyr PF07714.17 KXS15176.1 - 5.6e-72 242.1 0.0 2e-47 161.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXS15176.1 - 6e-60 202.8 0.0 8e-43 146.7 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Kinase-like PF14531.6 KXS15176.1 - 7.9e-07 28.7 0.0 1.1e-05 25.0 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KXS15176.1 - 8.6e-06 25.2 0.1 0.048 13.0 0.0 2.3 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KXS15176.1 - 0.00044 19.1 0.0 0.00088 18.1 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 KXS15176.1 - 0.0064 16.1 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 KXS15176.1 - 0.01 15.8 0.0 0.027 14.4 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ribosomal_L25p PF01386.19 KXS15179.1 - 0.082 13.4 0.0 0.088 13.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal L25p family zf-C3HC4_3 PF13920.6 KXS15180.1 - 0.03 14.2 8.1 0.051 13.4 8.1 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RNA_polI_A34 PF08208.11 KXS15180.1 - 0.14 12.3 3.1 0.33 11.0 3.1 1.7 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 zf-MYND PF01753.18 KXS15181.1 - 2e-07 31.0 3.9 3.7e-07 30.1 3.9 1.5 1 0 0 1 1 1 1 MYND finger Abhydrolase_3 PF07859.13 KXS15182.1 - 3.7e-39 134.8 0.0 5.1e-39 134.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KXS15182.1 - 1.1e-05 24.5 0.0 2.6e-05 23.3 0.0 1.6 1 1 0 1 1 1 1 Steryl acetyl hydrolase COesterase PF00135.28 KXS15182.1 - 0.0081 15.1 0.4 0.6 8.9 0.0 2.1 2 0 0 2 2 2 2 Carboxylesterase family TMP_2 PF06791.13 KXS15182.1 - 0.051 13.2 0.1 0.099 12.3 0.1 1.4 1 0 0 1 1 1 0 Prophage tail length tape measure protein DLH PF01738.18 KXS15182.1 - 0.15 11.6 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 Dienelactone hydrolase family BCS1_N PF08740.11 KXS15183.1 - 9.4e-34 117.0 0.0 1.3e-33 116.6 0.0 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 KXS15183.1 - 1.6e-17 64.2 0.0 2.8e-17 63.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KXS15183.1 - 0.0081 16.5 0.0 0.035 14.5 0.0 2.1 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 KXS15183.1 - 0.009 16.0 0.0 0.021 14.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF815 PF05673.13 KXS15183.1 - 0.018 14.2 0.0 0.039 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_28 PF13521.6 KXS15183.1 - 0.02 15.1 0.0 0.074 13.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 KXS15183.1 - 0.068 12.7 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 KXS15183.1 - 0.11 11.8 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 KaiC PPV_E1_C PF00519.17 KXS15183.1 - 0.14 10.9 0.0 0.22 10.3 0.0 1.1 1 0 0 1 1 1 0 Papillomavirus helicase AAA_7 PF12775.7 KXS15183.1 - 0.17 11.4 0.0 0.32 10.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region BCS1_N PF08740.11 KXS15184.1 - 2e-35 122.5 0.0 3.1e-35 121.9 0.0 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 KXS15184.1 - 9.4e-19 68.2 0.0 2.8e-18 66.6 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KXS15184.1 - 0.00025 21.5 0.0 0.00076 19.9 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.13 KXS15184.1 - 0.038 13.2 0.0 0.068 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_5 PF07728.14 KXS15184.1 - 0.048 13.7 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KXS15184.1 - 0.13 12.4 0.0 0.28 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KXS15184.1 - 0.18 11.3 0.0 0.32 10.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region V_ATPase_I PF01496.19 KXS15185.1 - 0 1054.2 0.0 0 1054.0 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family CheZ PF04344.13 KXS15185.1 - 0.018 15.0 0.5 0.018 15.0 0.5 1.8 2 0 0 2 2 2 0 Chemotaxis phosphatase, CheZ BBP1_C PF15272.6 KXS15185.1 - 0.13 12.1 2.7 2.4 7.9 0.3 2.1 2 0 0 2 2 2 0 Spindle pole body component BBP1, C-terminal FlaC_arch PF05377.11 KXS15185.1 - 5.8 7.4 8.3 13 6.2 0.6 3.4 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) DCX PF03607.17 KXS15187.1 - 2e-29 101.5 0.0 2.4e-13 50.0 0.0 2.3 2 0 0 2 2 2 2 Doublecortin UB2H PF14814.6 KXS15187.1 - 0.019 15.0 0.0 8 6.6 0.0 2.7 3 0 0 3 3 3 0 Bifunctional transglycosylase second domain CHASE9 PF17153.4 KXS15187.1 - 0.047 13.8 0.0 0.12 12.5 0.0 1.7 1 0 0 1 1 1 0 Periplasmic sensor domain, extracellular AAA_assoc_C PF09821.9 KXS15188.1 - 0.091 13.3 0.1 0.13 12.8 0.1 1.2 1 0 0 1 1 1 0 C-terminal AAA-associated domain MFS_1 PF07690.16 KXS15189.1 - 1.6e-20 73.4 43.6 1.9e-20 73.1 38.9 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily BNIP2 PF12496.8 KXS15190.1 - 0.14 12.5 7.5 0.21 12.0 7.5 1.2 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 SDA1 PF05285.12 KXS15190.1 - 0.28 10.6 7.9 0.31 10.4 7.9 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 KXS15190.1 - 0.3 9.3 6.6 0.36 9.1 6.6 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF3835 PF12927.7 KXS15190.1 - 1.3 9.9 0.1 1.3 9.9 0.1 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF3835) ParBc PF02195.18 KXS15191.1 - 2.3e-05 24.6 0.0 4e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 ParB-like nuclease domain EIF_2_alpha PF07541.12 KXS15191.1 - 0.063 13.4 0.0 0.065 13.3 0.0 1.3 1 1 0 1 1 1 0 Eukaryotic translation initiation factor 2 alpha subunit zf-C2H2 PF00096.26 KXS15192.1 - 2.4e-08 34.0 4.8 4.2e-05 23.8 0.7 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXS15192.1 - 2e-06 28.1 3.9 0.0004 21.0 0.4 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KXS15192.1 - 4.2e-05 23.4 0.6 4.2e-05 23.4 0.6 2.2 2 1 0 2 2 2 1 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KXS15192.1 - 0.00047 20.5 12.2 0.0013 19.1 1.4 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-met PF12874.7 KXS15192.1 - 0.0027 18.1 2.7 0.0098 16.3 0.6 2.1 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KXS15192.1 - 0.0066 16.7 5.6 0.0077 16.5 2.8 2.2 2 1 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-DNA_Pol PF08996.10 KXS15192.1 - 0.038 13.7 1.5 0.037 13.8 1.5 1.0 1 0 0 1 1 1 0 DNA Polymerase alpha zinc finger Gin PF10764.9 KXS15192.1 - 0.059 13.3 0.1 0.059 13.3 0.1 1.6 2 0 0 2 2 2 0 Inhibitor of sigma-G Gin MCM_OB PF17207.3 KXS15192.1 - 0.17 11.8 1.0 0.17 11.7 1.0 1.1 1 0 0 1 1 1 0 MCM OB domain zf-C2H2 PF00096.26 KXS15193.1 - 8.1e-28 95.3 25.2 3.1e-06 27.3 1.0 5.1 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KXS15193.1 - 2.2e-24 84.7 29.0 6.4e-07 29.5 0.4 6.0 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 KXS15193.1 - 2.2e-15 56.0 23.4 0.013 16.3 0.5 5.1 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 KXS15193.1 - 1.8e-08 34.7 14.2 0.078 13.1 0.4 4.5 3 1 1 5 5 5 4 Aberrant zinc-finger zf-C2H2_8 PF15909.5 KXS15193.1 - 9.4e-06 25.8 11.0 0.019 15.3 0.3 3.0 1 1 2 3 3 3 3 C2H2-type zinc ribbon zf-TRAF PF02176.18 KXS15193.1 - 0.00066 20.3 17.4 0.056 14.2 2.0 4.0 2 2 2 4 4 4 2 TRAF-type zinc finger zf-met PF12874.7 KXS15193.1 - 0.00093 19.5 7.0 0.57 10.7 0.1 4.8 5 0 0 5 5 5 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KXS15193.1 - 0.0055 16.9 6.6 2.7 8.4 0.2 4.0 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 KXS15193.1 - 0.038 14.6 7.4 30 5.3 0.1 4.7 1 1 4 5 5 5 0 FOXP coiled-coil domain gpW PF02831.15 KXS15193.1 - 0.23 11.4 0.0 5 7.1 0.0 2.1 2 0 0 2 2 2 0 gpW CCAP PF11105.8 KXS15193.1 - 0.7 9.9 3.8 14 5.7 0.3 2.2 1 1 0 2 2 2 0 Arthropod cardioacceleratory peptide 2a OrsD PF12013.8 KXS15193.1 - 1.7 9.1 10.7 11 6.6 0.3 3.9 1 1 4 5 5 5 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2H2_11 PF16622.5 KXS15193.1 - 5.8 6.8 14.4 0.62 9.9 0.4 4.1 5 0 0 5 5 5 0 zinc-finger C2H2-type DUF1768 PF08719.11 KXS15194.1 - 1.1e-50 172.0 0.0 1.3e-50 171.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Phage_30_3 PF08010.11 KXS15194.1 - 0.15 11.9 0.0 0.21 11.4 0.0 1.4 1 1 0 1 1 1 0 Bacteriophage protein GP30.3 Pkinase PF00069.25 KXS15195.1 - 5.7e-28 98.0 0.0 6.5e-28 97.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS15195.1 - 4.2e-23 82.0 0.0 4.8e-23 81.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXS15195.1 - 0.036 12.8 0.0 0.045 12.5 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 KXS15195.1 - 0.2 10.9 0.0 0.28 10.4 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Sel1 PF08238.12 KXS15196.1 - 6.5e-89 290.4 34.5 3.2e-11 43.5 0.4 9.5 9 1 1 10 10 10 9 Sel1 repeat TPR_6 PF13174.6 KXS15196.1 - 0.00042 20.8 6.1 5 8.0 0.0 5.4 6 1 0 6 6 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KXS15196.1 - 0.0016 18.6 5.5 0.23 11.7 0.5 4.3 4 1 1 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 SPO22 PF08631.10 KXS15196.1 - 0.0025 17.4 2.2 0.98 8.8 0.0 3.8 3 1 1 4 4 4 1 Meiosis protein SPO22/ZIP4 like TPR_11 PF13414.6 KXS15196.1 - 0.0027 17.4 18.8 0.4 10.4 0.6 6.7 8 0 0 8 8 8 3 TPR repeat TPR_16 PF13432.6 KXS15196.1 - 0.0096 16.5 3.0 30 5.4 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat Fib_succ_major PF09603.10 KXS15196.1 - 0.02 15.5 38.4 11 6.6 1.8 7.5 1 1 6 7 7 7 0 Fibrobacter succinogenes major domain (Fib_succ_major) Capsule_synth PF05159.14 KXS15196.1 - 0.034 13.6 2.8 6.6 6.1 0.1 3.5 3 1 1 4 4 4 0 Capsule polysaccharide biosynthesis protein TPR_17 PF13431.6 KXS15196.1 - 0.14 12.6 10.7 37 5.0 0.3 6.4 5 2 2 7 7 7 0 Tetratricopeptide repeat Gsf2 PF11055.8 KXS15196.1 - 0.3 9.8 5.8 5.2 5.7 0.2 3.7 1 1 4 5 5 5 0 Glucose signalling factor 2 TPR_1 PF00515.28 KXS15196.1 - 1.5 8.7 34.1 0.62 10.0 0.4 8.9 11 0 0 11 11 11 0 Tetratricopeptide repeat zf-H2C2_2 PF13465.6 KXS15197.1 - 1.9e-13 50.2 2.1 4e-06 27.0 0.0 2.3 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 KXS15197.1 - 6.7e-13 48.3 4.5 0.00026 21.3 0.0 3.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXS15197.1 - 5.3e-08 33.0 3.9 0.0063 17.3 0.1 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KXS15197.1 - 0.00023 21.4 0.9 0.066 13.5 0.1 2.8 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 KXS15197.1 - 0.0057 16.9 0.3 0.011 16.0 0.3 1.5 1 1 0 1 1 1 1 C2H2-type zinc ribbon zf-met PF12874.7 KXS15197.1 - 0.0089 16.4 0.6 0.3 11.5 0.0 3.1 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_aberr PF17017.5 KXS15197.1 - 0.0092 16.1 3.1 1.2 9.3 0.2 2.1 1 1 1 2 2 2 2 Aberrant zinc-finger zf-C2H2_6 PF13912.6 KXS15197.1 - 0.023 14.7 5.4 2.1 8.4 0.0 3.0 3 1 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KXS15198.1 - 7.9e-18 64.0 16.4 2.1e-05 24.8 0.1 5.2 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.26 KXS15198.1 - 1.5e-17 63.0 20.6 0.00013 22.2 0.2 5.6 5 1 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXS15198.1 - 4.2e-09 36.5 18.2 0.2 12.6 0.2 5.3 5 0 0 5 5 5 3 C2H2-type zinc finger zf_Hakai PF18408.1 KXS15198.1 - 0.00015 21.4 5.0 2.2 8.0 0.0 4.5 4 0 0 4 4 4 2 C2H2 Hakai zinc finger domain zf-C2H2_8 PF15909.5 KXS15198.1 - 0.0002 21.6 6.9 0.00042 20.6 3.0 2.6 1 1 2 3 3 3 2 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 KXS15198.1 - 0.081 13.2 6.1 5.7 7.4 0.0 4.2 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding VKOR PF07884.14 KXS15198.1 - 0.094 12.9 3.8 16 5.7 0.1 3.4 1 1 3 4 4 4 0 Vitamin K epoxide reductase family DUF3268 PF11672.8 KXS15198.1 - 0.54 10.6 8.3 1.5 9.2 0.7 3.0 1 1 3 4 4 4 0 zinc-finger-containing domain zf-CGNR PF11706.8 KXS15198.1 - 2.5 8.0 9.7 9 6.2 0.1 3.8 4 0 0 4 4 4 0 CGNR zinc finger zf-C2H2_6 PF13912.6 KXS15198.1 - 3.8 7.6 7.6 7.9 6.6 0.2 3.7 3 1 0 3 3 3 0 C2H2-type zinc finger LRR_8 PF13855.6 KXS15202.1 - 2.9e-20 71.8 7.3 1.4e-06 27.9 0.0 3.5 3 0 0 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 KXS15202.1 - 5.4e-18 64.8 5.3 3.8e-05 24.0 2.7 3.9 3 1 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KXS15202.1 - 1.3e-08 34.2 1.0 4.4 8.2 0.0 6.0 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_9 PF14580.6 KXS15202.1 - 4e-05 23.2 0.0 0.0061 16.1 0.0 2.2 2 0 0 2 2 2 2 Leucine-rich repeat EIN3 PF04873.13 KXS15202.1 - 0.026 13.8 0.1 0.044 13.1 0.1 1.3 1 0 0 1 1 1 0 Ethylene insensitive 3 LRR_6 PF13516.6 KXS15202.1 - 0.042 13.9 15.2 2 8.7 0.4 6.2 7 0 0 7 7 7 0 Leucine Rich repeat G-patch PF01585.23 KXS15204.1 - 1.8e-13 50.1 0.3 1e-12 47.7 0.3 2.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KXS15204.1 - 8.1e-08 32.2 0.5 8.1e-08 32.2 0.5 4.9 7 0 0 7 7 7 1 G-patch domain DEC-1_N PF04625.13 KXS15204.1 - 0.15 11.0 3.8 0.28 10.2 3.8 1.4 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region zf-MYND PF01753.18 KXS15206.1 - 4.3e-09 36.3 11.1 6.2e-09 35.8 11.1 1.3 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KXS15206.1 - 0.027 14.8 6.9 0.039 14.3 6.9 1.3 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Opi1 PF08618.10 KXS15207.1 - 2.4e-08 33.7 9.8 4.8e-07 29.4 0.0 3.4 3 0 0 3 3 3 2 Transcription factor Opi1 Glyco_hydro_28 PF00295.17 KXS15208.1 - 3.3e-10 39.5 0.0 4.1e-10 39.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 2OG-FeII_Oxy_3 PF13640.6 KXS15209.1 - 1.1e-09 39.1 0.0 2e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 KXS15209.1 - 0.054 14.0 0.0 0.1 13.1 0.0 1.4 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily F-box PF00646.33 KXS15210.1 - 0.05 13.5 0.4 0.16 11.8 0.1 2.1 1 1 0 1 1 1 0 F-box domain LRR_2 PF07723.13 KXS15210.1 - 0.32 11.7 3.3 16 6.3 0.2 2.6 2 0 0 2 2 2 0 Leucine Rich Repeat DNA_pol_phi PF04931.13 KXS15211.1 - 0.17 9.9 1.9 0.21 9.6 1.9 1.0 1 0 0 1 1 1 0 DNA polymerase phi Thioredoxin PF00085.20 KXS15212.1 - 3.3e-28 97.7 0.1 4.6e-28 97.2 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 KXS15212.1 - 2.6e-07 30.9 0.0 3e-06 27.5 0.0 2.0 1 1 1 2 2 2 1 Thioredoxin-like AhpC-TSA PF00578.21 KXS15212.1 - 3.4e-05 23.7 0.1 8.4e-05 22.5 0.1 1.6 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_2 PF13098.6 KXS15212.1 - 5.6e-05 23.5 0.1 0.00054 20.4 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 KXS15212.1 - 0.00034 20.1 0.0 0.00048 19.6 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Redoxin PF08534.10 KXS15212.1 - 0.0043 16.8 0.1 0.0082 15.9 0.1 1.5 1 1 0 1 1 1 1 Redoxin Phosducin PF02114.16 KXS15212.1 - 0.013 14.5 0.0 0.015 14.2 0.0 1.1 1 0 0 1 1 1 0 Phosducin Thioredoxin_9 PF14595.6 KXS15212.1 - 0.022 14.5 0.0 0.027 14.3 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_7 PF13899.6 KXS15212.1 - 0.1 12.8 0.1 0.29 11.3 0.1 1.7 1 1 0 1 1 1 0 Thioredoxin-like TraF PF13728.6 KXS15212.1 - 0.13 12.1 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 F plasmid transfer operon protein TatD_DNase PF01026.21 KXS15213.1 - 2.2e-52 178.0 0.1 2.9e-52 177.6 0.1 1.1 1 0 0 1 1 1 1 TatD related DNase EF-hand_1 PF00036.32 KXS15214.1 - 4.8e-16 57.0 11.7 1.8e-06 27.1 0.8 4.2 3 1 1 4 4 4 3 EF hand EF-hand_7 PF13499.6 KXS15214.1 - 2.3e-14 53.6 8.4 8.7e-09 35.7 1.1 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KXS15214.1 - 6.1e-14 50.8 4.6 0.00024 20.5 0.1 4.4 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 KXS15214.1 - 5.2e-12 44.7 9.9 0.0002 21.0 0.7 4.4 4 1 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 KXS15214.1 - 8.5e-09 35.1 13.6 0.00019 21.2 2.3 4.4 2 2 1 3 3 3 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KXS15214.1 - 0.013 15.8 2.4 0.11 12.8 0.3 2.5 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KXS15214.1 - 0.078 12.9 1.6 0.37 10.8 0.3 2.1 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 KXS15214.1 - 0.38 11.0 4.5 0.81 9.9 1.5 2.4 2 1 0 2 2 2 0 Dockerin type I domain EGF_MSP1_1 PF12946.7 KXS15216.1 - 0.84 9.7 11.7 3.2 7.9 0.8 2.3 2 0 0 2 2 2 0 MSP1 EGF domain 1 EGF_2 PF07974.13 KXS15216.1 - 6.2 7.3 18.4 0.39 11.1 1.9 2.5 1 1 1 2 2 2 0 EGF-like domain EGF_3 PF12947.7 KXS15216.1 - 7.8 6.8 14.9 33 4.8 6.2 2.3 1 1 1 2 2 2 0 EGF domain Phi_1 PF04674.12 KXS15217.1 - 1.1e-11 44.6 0.0 3.1e-11 43.1 0.0 1.7 2 0 0 2 2 2 1 Phosphate-induced protein 1 conserved region LRR_4 PF12799.7 KXS15217.1 - 0.00092 19.6 1.7 0.018 15.4 0.2 3.3 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) Oxidored-like PF09791.9 KXS15217.1 - 0.8 9.4 6.7 1.9 8.2 6.7 1.5 1 0 0 1 1 1 0 Oxidoreductase-like protein, N-terminal PH PF00169.29 KXS15219.1 - 0.00029 21.3 0.1 0.076 13.5 0.3 2.3 2 0 0 2 2 2 2 PH domain DUF4170 PF13773.6 KXS15220.1 - 0.067 13.3 0.0 0.16 12.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4170) 2-Hacid_dh_C PF02826.19 KXS15222.1 - 6.6e-47 159.2 0.0 1.2e-46 158.3 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KXS15222.1 - 7.5e-14 51.5 0.0 8.9e-14 51.3 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KXS15222.1 - 0.00073 19.7 0.0 0.0019 18.4 0.0 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KXS15222.1 - 0.0025 18.4 0.0 0.0065 17.0 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent AdoHcyase_NAD PF00670.21 KXS15222.1 - 0.0076 16.3 0.2 0.035 14.2 0.2 2.0 1 1 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ThiF PF00899.21 KXS15222.1 - 0.3 10.4 2.3 0.66 9.3 1.0 1.9 2 0 0 2 2 2 0 ThiF family Thiolase_N PF00108.23 KXS15223.1 - 2e-69 233.9 0.7 2.5e-69 233.5 0.7 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KXS15223.1 - 4.7e-43 145.7 0.5 9.9e-43 144.7 0.2 1.7 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KXS15223.1 - 5e-05 23.0 3.7 0.0002 21.0 1.6 2.6 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KXS15223.1 - 0.22 11.4 1.8 0.32 10.9 0.2 2.0 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Med13_C PF06333.12 KXS15224.1 - 0.041 13.2 2.6 0.048 12.9 2.6 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain Thioredoxin PF00085.20 KXS15225.1 - 1.3e-14 54.0 0.0 1.6e-14 53.7 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 KXS15225.1 - 0.0026 18.1 0.0 0.0036 17.6 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 KXS15225.1 - 0.019 14.7 0.0 0.026 14.2 0.0 1.3 1 0 0 1 1 1 0 Redoxin Glutaredoxin PF00462.24 KXS15225.1 - 0.097 12.9 0.0 0.29 11.4 0.0 1.8 2 0 0 2 2 2 0 Glutaredoxin DUF953 PF06110.11 KXS15225.1 - 0.1 12.2 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) AhpC-TSA PF00578.21 KXS15225.1 - 0.11 12.4 0.0 0.11 12.4 0.0 1.3 1 1 0 1 1 1 0 AhpC/TSA family PAPS_reduct PF01507.19 KXS15227.1 - 1.6e-29 103.2 0.0 1.8e-17 64.0 0.0 2.2 1 1 1 2 2 2 2 Phosphoadenosine phosphosulfate reductase family MoCF_biosynth PF00994.24 KXS15227.1 - 2.4e-25 88.9 0.0 6.3e-25 87.5 0.0 1.7 2 0 0 2 2 2 1 Probable molybdopterin binding domain zf-C2H2 PF00096.26 KXS15228.1 - 8.2e-08 32.3 10.3 0.00082 19.7 0.6 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KXS15228.1 - 2.7e-06 27.5 4.1 2.7e-06 27.5 4.1 3.5 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KXS15228.1 - 0.0015 19.2 10.2 0.045 14.6 0.7 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KXS15228.1 - 0.034 13.9 4.0 1.2 9.0 0.6 2.6 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-met PF12874.7 KXS15228.1 - 0.84 10.1 3.6 20 5.8 0.5 3.2 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-Di19 PF05605.12 KXS15229.1 - 0.00064 20.0 0.4 0.00064 20.0 0.4 2.4 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.6 KXS15229.1 - 0.00075 19.8 0.4 0.00075 19.8 0.4 2.6 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KXS15229.1 - 0.0011 19.6 8.7 0.02 15.7 1.6 2.9 3 0 0 3 3 3 2 C2H2-type zinc finger zf_C2H2_10 PF18414.1 KXS15229.1 - 0.0052 16.3 2.1 0.079 12.5 0.0 2.3 2 0 0 2 2 2 1 C2H2 type zinc-finger zf-C2H2_8 PF15909.5 KXS15229.1 - 0.019 15.2 1.4 0.11 12.8 1.0 2.3 2 1 1 3 3 3 0 C2H2-type zinc ribbon GAGA PF09237.11 KXS15229.1 - 0.034 14.0 0.4 1.1 9.2 0.5 2.4 2 0 0 2 2 2 0 GAGA factor zf-C2H2 PF00096.26 KXS15229.1 - 0.25 11.9 10.7 0.65 10.6 1.4 3.1 3 0 0 3 3 3 0 Zinc finger, C2H2 type FOXP-CC PF16159.5 KXS15229.1 - 1.8 9.2 9.8 3.3 8.4 1.2 3.3 2 1 1 3 3 3 0 FOXP coiled-coil domain APG5 PF04106.12 KXS15230.1 - 1.2e-44 152.6 0.0 1.6e-44 152.2 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg5 Herpes_pp85 PF04637.12 KXS15230.1 - 0.032 12.6 4.4 0.013 14.0 1.8 1.6 1 1 1 2 2 2 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) NmrA PF05368.13 KXS15231.1 - 1.2e-21 77.3 0.1 1.5e-21 77.0 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXS15231.1 - 3.2e-08 33.7 0.1 9.2e-08 32.2 0.1 1.8 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KXS15231.1 - 0.00043 19.8 0.1 0.077 12.4 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXS15231.1 - 0.016 14.2 0.0 0.024 13.7 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family GYF_2 PF14237.6 KXS15232.1 - 0.17 11.7 0.1 0.43 10.4 0.1 1.6 1 0 0 1 1 1 0 GYF domain 2 Cellulase PF00150.18 KXS15233.1 - 1.7e-13 50.7 0.0 2.4e-08 33.8 0.0 3.1 3 0 0 3 3 3 3 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_5_C PF18564.1 KXS15233.1 - 1.7e-12 47.7 0.2 5e-12 46.2 0.2 1.8 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain AMP-binding PF00501.28 KXS15234.1 - 4.8e-61 206.6 0.0 1.3e-35 122.8 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 KXS15234.1 - 2.8e-05 25.0 0.0 6.8e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DEAD PF00270.29 KXS15236.1 - 1.6e-16 60.6 0.0 2e-16 60.3 0.0 1.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase DEAD PF00270.29 KXS15237.1 - 6.9e-45 153.0 0.0 1.1e-44 152.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXS15237.1 - 8.9e-19 67.9 0.0 2.7e-18 66.4 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXS15237.1 - 0.0016 18.4 0.0 0.0025 17.8 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-CHY PF05495.12 KXS15238.1 - 1.5e-09 38.2 14.3 3.2e-09 37.1 14.3 1.7 1 1 0 1 1 1 1 CHY zinc finger GPCR_chapero_1 PF11904.8 KXS15239.1 - 2.7e-42 145.3 0.0 2.8e-26 92.7 0.0 2.1 2 0 0 2 2 2 2 GPCR-chaperone Ank_2 PF12796.7 KXS15239.1 - 2.6e-07 31.1 0.0 5.9e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXS15239.1 - 9.3e-07 29.3 0.0 4.1e-06 27.2 0.0 2.1 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXS15239.1 - 1.5e-06 28.3 0.0 3.9e-06 27.0 0.0 1.7 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXS15239.1 - 3.3e-06 27.0 0.0 0.0033 17.8 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 KXS15239.1 - 1.5e-05 25.2 0.0 3.9e-05 23.9 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeat CX9C PF16860.5 KXS15240.1 - 2.1e-05 24.4 1.0 0.11 12.6 0.1 2.2 1 1 1 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, UPF0203 PF05254.12 KXS15240.1 - 0.0069 16.6 0.5 0.066 13.5 0.6 1.9 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0203) UCR_hinge PF02320.16 KXS15240.1 - 0.012 15.7 0.4 0.017 15.3 0.4 1.3 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase hinge protein CHCH PF06747.13 KXS15240.1 - 0.06 13.5 1.2 0.18 12.0 0.5 1.9 2 0 0 2 2 2 0 CHCH domain DSHCT PF08148.12 KXS15244.1 - 3e-48 163.6 0.8 3.1e-47 160.3 0.4 2.3 2 0 0 2 2 2 1 DSHCT (NUC185) domain rRNA_proc-arch PF13234.6 KXS15244.1 - 9.8e-29 101.1 0.0 1.6e-28 100.4 0.0 1.3 1 0 0 1 1 1 1 rRNA-processing arch domain Ski2_N PF17911.1 KXS15244.1 - 2.1e-23 82.6 0.0 4.6e-23 81.5 0.0 1.6 1 0 0 1 1 1 1 Ski2 N-terminal region DEAD PF00270.29 KXS15244.1 - 1.3e-17 64.1 0.0 2.6e-17 63.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXS15244.1 - 1e-05 25.8 0.0 2.8e-05 24.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXS15244.1 - 1.5e-05 25.1 0.0 2.7e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF3516 PF12029.8 KXS15244.1 - 0.0078 15.3 0.0 0.013 14.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3516) zf-C2H2_4 PF13894.6 KXS15245.1 - 0.013 16.2 7.5 0.065 14.1 1.1 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KXS15245.1 - 0.018 15.5 9.1 0.021 15.3 1.5 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KXS15245.1 - 0.044 14.2 1.2 0.044 14.2 1.2 2.6 2 0 0 2 2 2 0 Zinc-finger double domain Sfi1_C PF10638.9 KXS15245.1 - 0.048 14.4 0.0 0.096 13.5 0.0 1.4 1 0 0 1 1 1 0 Spindle body associated protein C-terminus WD40 PF00400.32 KXS15246.1 - 4.8e-07 30.4 0.1 0.00058 20.6 0.0 4.0 3 0 0 3 3 3 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXS15246.1 - 8.4e-05 22.8 0.0 2.5 8.5 0.0 4.0 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Gmad1 PF10647.9 KXS15246.1 - 0.031 14.0 0.7 0.061 13.1 0.7 1.4 1 0 0 1 1 1 0 Lipoprotein LpqB beta-propeller domain SET PF00856.28 KXS15247.1 - 9.6e-11 42.4 0.1 2.7e-10 40.9 0.0 1.6 2 0 0 2 2 2 1 SET domain SWIRM-assoc_2 PF16496.5 KXS15247.1 - 0.09 11.6 1.9 0.11 11.4 1.9 1.1 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal Chromo PF00385.24 KXS15249.1 - 2.6e-08 33.6 0.1 5.2e-08 32.7 0.1 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain 2OG-FeII_Oxy_3 PF13640.6 KXS15250.1 - 3.7e-08 34.2 0.0 6.7e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Copper-fist PF00649.18 KXS15251.1 - 2.8e-12 45.9 0.8 2.8e-12 45.9 0.8 2.1 1 1 1 2 2 2 2 Copper fist DNA binding domain Thiolase_N PF00108.23 KXS15252.1 - 8.4e-15 54.8 0.0 7.7e-13 48.4 0.0 2.6 2 1 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KXS15252.1 - 5.6e-11 42.2 0.0 1.5e-10 40.8 0.0 1.8 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KXS15252.1 - 3.8e-05 23.4 4.1 0.0045 16.6 0.2 3.1 2 1 1 3 3 3 2 Beta-ketoacyl synthase, N-terminal domain SpoVAD PF07451.11 KXS15252.1 - 0.0014 17.4 0.7 0.019 13.7 0.1 2.1 2 0 0 2 2 2 1 Stage V sporulation protein AD (SpoVAD) ACP_syn_III PF08545.10 KXS15252.1 - 0.0036 17.1 2.2 0.045 13.6 0.1 3.0 2 1 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III HMG_CoA_synt_N PF01154.17 KXS15252.1 - 0.029 14.2 0.0 0.064 13.1 0.0 1.5 1 0 0 1 1 1 0 Hydroxymethylglutaryl-coenzyme A synthase N terminal Ketoacyl-synt_C PF02801.22 KXS15252.1 - 0.067 13.2 1.0 1.1 9.3 0.1 2.7 3 0 0 3 3 3 0 Beta-ketoacyl synthase, C-terminal domain bZIP_1 PF00170.21 KXS15253.1 - 0.0025 17.9 1.9 0.36 11.0 0.3 2.1 2 0 0 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.15 KXS15253.1 - 0.0071 16.4 7.0 0.016 15.2 2.8 2.1 2 0 0 2 2 2 1 Basic region leucine zipper MbeD_MobD PF04899.12 KXS15253.1 - 0.022 14.9 0.2 0.37 10.9 0.0 2.1 2 0 0 2 2 2 0 MbeD/MobD like DUF4140 PF13600.6 KXS15253.1 - 0.061 13.8 1.1 0.098 13.1 1.1 1.4 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DASH_Dad3 PF08656.10 KXS15253.1 - 0.071 13.2 0.4 0.14 12.2 0.4 1.4 1 1 0 1 1 1 0 DASH complex subunit Dad3 DUF3138 PF11336.8 KXS15253.1 - 0.1 11.2 0.3 0.11 11.1 0.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Med21 PF11221.8 KXS15253.1 - 0.12 12.6 1.5 1.2 9.4 0.7 2.0 2 0 0 2 2 2 0 Subunit 21 of Mediator complex BST2 PF16716.5 KXS15253.1 - 0.12 12.9 2.2 0.25 12.0 0.3 1.9 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 SIKE PF05769.11 KXS15253.1 - 0.13 12.2 3.0 0.69 9.8 2.8 1.8 1 1 0 1 1 1 0 SIKE family NYD-SP28_assoc PF14775.6 KXS15253.1 - 0.13 12.4 3.2 0.31 11.2 0.6 2.0 2 0 0 2 2 2 0 Sperm tail C-terminal domain Glyco_hydro_45 PF02015.16 KXS15254.1 - 2.8e-66 223.4 18.2 3.8e-66 223.0 18.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 Glyco_hydro_45 PF02015.16 KXS15255.1 - 4.3e-63 213.0 15.9 4.3e-63 213.0 15.9 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 45 Glyco_hydro_45 PF02015.16 KXS15256.1 - 2.5e-63 213.8 16.6 6.7e-63 212.4 16.6 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 Peptidase_C28 PF05408.11 KXS15256.1 - 0.00029 20.6 0.2 2 8.1 0.1 3.4 3 0 0 3 3 3 3 Foot-and-mouth virus L-proteinase HAUS-augmin3 PF14932.6 KXS15257.1 - 0.007 16.0 1.4 0.045 13.3 0.5 2.0 2 0 0 2 2 2 1 HAUS augmin-like complex subunit 3 TMF_DNA_bd PF12329.8 KXS15257.1 - 0.04 13.9 1.3 0.04 13.9 1.3 1.9 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding ATG16 PF08614.11 KXS15257.1 - 0.04 14.1 0.1 0.04 14.1 0.1 2.0 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) MnmE_helical PF12631.7 KXS15257.1 - 0.099 12.8 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 MnmE helical domain DUF16 PF01519.16 KXS15257.1 - 0.1 13.1 0.3 0.4 11.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function DUF16 DUF5082 PF16888.5 KXS15257.1 - 0.2 11.9 1.1 0.5 10.7 0.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) CLZ PF16526.5 KXS15257.1 - 0.34 11.3 5.0 0.37 11.2 1.2 2.6 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ERM PF00769.19 KXS15257.1 - 1.6 8.5 7.0 1.5 8.5 0.7 2.1 2 0 0 2 2 2 0 Ezrin/radixin/moesin family DUF4164 PF13747.6 KXS15257.1 - 2.1 8.7 10.2 1.3 9.4 3.5 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4164) DHR10 PF18595.1 KXS15257.1 - 3.8 7.6 11.2 3.1 7.9 4.5 2.4 2 1 0 2 2 2 0 Designed helical repeat protein 10 domain SlyX PF04102.12 KXS15257.1 - 8.8 7.0 8.2 6.2 7.5 0.1 3.5 4 0 0 4 4 4 0 SlyX BLOC1_2 PF10046.9 KXS15258.1 - 8.8e-05 22.7 0.9 0.00013 22.2 0.9 1.3 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Mto2_bdg PF12808.7 KXS15258.1 - 0.00015 22.0 1.2 0.00046 20.4 1.2 1.8 1 1 0 1 1 1 1 Micro-tubular organiser Mto1 C-term Mto2-binding region SIKE PF05769.11 KXS15258.1 - 0.00098 19.1 0.6 0.0012 18.9 0.6 1.1 1 0 0 1 1 1 1 SIKE family bZIP_2 PF07716.15 KXS15258.1 - 0.001 19.1 2.8 0.01 15.9 0.8 2.2 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 KXS15258.1 - 0.0017 18.4 2.6 0.015 15.3 1.2 2.1 2 0 0 2 2 2 1 bZIP transcription factor FlaC_arch PF05377.11 KXS15258.1 - 0.0019 18.6 3.1 0.018 15.4 0.6 2.1 2 0 0 2 2 2 1 Flagella accessory protein C (FlaC) Syntaxin-6_N PF09177.11 KXS15258.1 - 0.0022 18.5 1.5 0.0026 18.3 1.5 1.1 1 0 0 1 1 1 1 Syntaxin 6, N-terminal Med21 PF11221.8 KXS15258.1 - 0.0037 17.5 2.1 0.0048 17.2 2.1 1.2 1 0 0 1 1 1 1 Subunit 21 of Mediator complex Uso1_p115_C PF04871.13 KXS15258.1 - 0.0053 17.1 2.4 0.0062 16.9 2.4 1.1 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, C terminal region TACC_C PF05010.14 KXS15258.1 - 0.0055 16.5 1.1 0.007 16.2 1.1 1.1 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal FAM150 PF15129.6 KXS15258.1 - 0.0074 16.4 0.4 0.0082 16.3 0.4 1.1 1 0 0 1 1 1 1 FAM150 family GAS PF13851.6 KXS15258.1 - 0.009 15.4 3.7 0.024 14.0 3.7 1.7 1 1 0 1 1 1 1 Growth-arrest specific micro-tubule binding DUF2730 PF10805.8 KXS15258.1 - 0.011 15.8 1.3 0.014 15.4 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) DUF2046 PF09755.9 KXS15258.1 - 0.012 14.9 2.6 0.034 13.4 0.8 1.8 1 1 1 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) DivIC PF04977.15 KXS15258.1 - 0.016 15.0 1.6 0.45 10.3 1.0 2.1 2 0 0 2 2 2 0 Septum formation initiator CCDC-167 PF15188.6 KXS15258.1 - 0.021 15.1 2.9 0.026 14.8 2.9 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 Cnn_1N PF07989.11 KXS15258.1 - 0.024 14.8 6.8 0.3 11.3 5.8 2.6 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 HSBP1 PF06825.12 KXS15258.1 - 0.026 14.4 0.9 0.52 10.2 0.0 2.5 2 1 1 3 3 3 0 Heat shock factor binding protein 1 MtrB PF05440.12 KXS15258.1 - 0.036 14.5 0.2 6.1 7.3 0.1 2.1 1 1 1 2 2 2 0 Tetrahydromethanopterin S-methyltransferase subunit B DMPK_coil PF08826.10 KXS15258.1 - 0.039 14.1 3.5 0.05 13.7 1.3 1.9 1 1 1 2 2 2 0 DMPK coiled coil domain like PCRF PF03462.18 KXS15258.1 - 0.039 13.8 1.2 0.047 13.5 1.2 1.0 1 0 0 1 1 1 0 PCRF domain GIT_CC PF16559.5 KXS15258.1 - 0.052 13.4 0.6 0.13 12.1 0.1 1.8 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor ATG16 PF08614.11 KXS15258.1 - 0.052 13.8 5.1 0.27 11.4 5.2 1.8 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) FUSC-like PF12805.7 KXS15258.1 - 0.063 12.3 0.1 0.066 12.3 0.1 1.0 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS WD40_alt PF14077.6 KXS15258.1 - 0.064 13.1 5.1 5.6 6.9 0.0 3.0 2 1 1 3 3 3 0 Alternative WD40 repeat motif ZapB PF06005.12 KXS15258.1 - 0.064 13.7 3.4 0.16 12.5 3.4 1.6 1 1 0 1 1 1 0 Cell division protein ZapB Striatin PF08232.12 KXS15258.1 - 0.066 13.8 1.6 0.23 12.0 0.7 1.9 2 0 0 2 2 2 0 Striatin family Phage_GPO PF05929.11 KXS15258.1 - 0.071 12.7 0.9 0.079 12.6 0.9 1.0 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Anti-adapt_IraP PF10796.9 KXS15258.1 - 0.074 13.6 1.8 0.26 11.8 0.7 1.9 2 0 0 2 2 2 0 Sigma-S stabilisation anti-adaptor protein YabA PF06156.13 KXS15258.1 - 0.079 13.6 1.4 0.11 13.2 1.4 1.2 1 0 0 1 1 1 0 Initiation control protein YabA Thioredoxin_13 PF18401.1 KXS15258.1 - 0.093 12.6 1.1 0.48 10.3 1.1 1.9 1 1 0 1 1 1 0 Thioredoxin-like domain FliT PF05400.13 KXS15258.1 - 0.098 13.5 2.8 0.12 13.2 2.8 1.1 1 0 0 1 1 1 0 Flagellar protein FliT Allexi_40kDa PF05549.11 KXS15258.1 - 0.11 12.0 0.9 0.12 11.8 0.9 1.0 1 0 0 1 1 1 0 Allexivirus 40kDa protein DASH_Dam1 PF08653.10 KXS15258.1 - 0.12 12.1 0.0 3.9 7.4 0.0 2.1 2 0 0 2 2 2 0 DASH complex subunit Dam1 SlyX PF04102.12 KXS15258.1 - 0.13 12.9 3.8 7 7.4 0.1 2.5 1 1 0 2 2 2 0 SlyX CLZ PF16526.5 KXS15258.1 - 0.16 12.3 3.9 0.3 11.5 1.5 2.0 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels KLRAQ PF10205.9 KXS15258.1 - 0.19 12.0 4.2 0.26 11.6 1.5 1.9 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein Trimer_CC PF08954.11 KXS15258.1 - 0.19 11.3 5.0 0.13 11.9 2.8 1.8 1 1 1 2 2 2 0 Trimerisation motif IFP_35_N PF07334.13 KXS15258.1 - 0.34 11.0 3.3 0.2 11.8 1.3 1.6 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus PspB PF06667.12 KXS15258.1 - 0.4 10.8 4.0 10 6.2 0.8 2.3 1 1 1 2 2 2 0 Phage shock protein B TMF_DNA_bd PF12329.8 KXS15258.1 - 0.59 10.2 8.6 3.3 7.8 6.0 2.6 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding M PF02370.16 KXS15258.1 - 1.3 9.8 6.6 0.72 10.6 3.0 2.4 2 1 1 3 3 2 0 M protein repeat Pkinase PF00069.25 KXS15259.1 - 2.6e-66 223.7 0.0 6.1e-66 222.5 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS15259.1 - 5.1e-32 111.2 0.0 7e-32 110.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXS15259.1 - 0.00037 19.9 0.2 0.0011 18.4 0.0 1.9 2 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 KXS15259.1 - 0.00064 18.8 0.0 0.0013 17.8 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KXS15259.1 - 0.00067 19.1 0.1 0.0013 18.2 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXS15259.1 - 0.0022 17.9 0.1 0.0066 16.4 0.1 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KXS15259.1 - 0.0043 16.7 0.0 0.0087 15.7 0.0 1.6 1 0 0 1 1 1 1 RIO1 family Grp7_allergen PF16984.5 KXS15259.1 - 0.047 13.7 0.0 0.082 13.0 0.0 1.5 1 0 0 1 1 1 0 Group 7 allergen Aminotran_5 PF00266.19 KXS15260.1 - 1.7e-09 37.2 0.0 2.7e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V HRI1 PF16815.5 KXS15261.1 - 2.8e-26 92.6 0.0 3.2e-26 92.5 0.0 1.2 1 1 0 1 1 1 1 Protein HRI1 DUF21 PF01595.20 KXS15262.1 - 1.2e-37 129.3 0.6 2.8e-37 128.1 0.5 1.7 2 0 0 2 2 2 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 KXS15262.1 - 6.5e-07 29.7 0.3 0.28 11.7 0.0 3.7 3 0 0 3 3 3 3 CBS domain Pox_ser-thr_kin PF05445.11 KXS15263.1 - 0.15 11.0 0.0 0.21 10.5 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Abhydrolase_6 PF12697.7 KXS15264.1 - 4e-07 30.9 0.0 5.7e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXS15264.1 - 1.9e-05 24.1 0.1 4e-05 23.0 0.0 1.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KXS15264.1 - 0.00022 20.9 0.0 0.0003 20.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Ser_hydrolase PF06821.13 KXS15264.1 - 0.0032 17.4 0.0 0.006 16.5 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase Ribosomal_S13 PF00416.22 KXS15265.1 - 1.5e-55 187.0 2.9 1.8e-55 186.8 2.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 KXS15265.1 - 0.01 14.6 0.0 0.011 14.5 0.0 1.2 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) HHH_6 PF14579.6 KXS15265.1 - 0.06 13.6 0.0 0.19 12.0 0.0 1.9 1 1 0 1 1 1 0 Helix-hairpin-helix motif BET PF17035.5 KXS15265.1 - 0.083 13.1 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 Bromodomain extra-terminal - transcription regulation PP28 PF10252.9 KXS15265.1 - 0.091 13.2 0.6 0.18 12.3 0.6 1.5 1 0 0 1 1 1 0 Casein kinase substrate phosphoprotein PP28 F-box PF00646.33 KXS15266.1 - 3.4e-08 33.2 1.5 2.1e-07 30.6 0.2 2.7 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KXS15266.1 - 6.7e-07 29.1 0.3 6.7e-07 29.1 0.3 2.5 2 0 0 2 2 2 1 F-box-like p450 PF00067.22 KXS15272.1 - 4.9e-54 183.8 0.0 9.7e-54 182.8 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 UPF0060 PF02694.15 KXS15275.1 - 0.096 12.9 0.0 0.14 12.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised BCR, YnfA/UPF0060 family CRAL_TRIO PF00650.20 KXS15276.1 - 6.7e-36 123.4 0.0 8.4e-36 123.1 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KXS15276.1 - 7.9e-09 35.6 0.7 2e-08 34.3 0.7 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KXS15276.1 - 9.3e-07 29.1 0.0 1.3e-06 28.6 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain zf-C3H1 PF10650.9 KXS15277.1 - 2.6e-08 33.4 1.4 4.7e-08 32.6 1.4 1.5 1 0 0 1 1 1 1 Putative zinc-finger domain NRDE-2 PF08424.10 KXS15277.1 - 5.8e-06 25.7 0.3 1.8e-05 24.1 0.3 1.8 1 0 0 1 1 1 1 NRDE-2, necessary for RNA interference DUF4201 PF13870.6 KXS15277.1 - 5.6 6.7 13.7 1.7 8.4 6.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) Shikimate_dh_N PF08501.11 KXS15278.1 - 2.4e-20 72.6 0.0 4.6e-20 71.7 0.0 1.5 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Robl_LC7 PF03259.17 KXS15278.1 - 0.002 17.8 0.2 0.0063 16.3 0.2 1.8 1 0 0 1 1 1 1 Roadblock/LC7 domain OCD_Mu_crystall PF02423.15 KXS15278.1 - 0.11 11.4 0.0 0.16 10.8 0.0 1.1 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family CNH PF00780.22 KXS15279.1 - 3.3e-61 207.3 0.0 6.2e-61 206.4 0.0 1.4 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.20 KXS15279.1 - 4.7e-24 85.6 0.0 6.7e-24 85.1 0.0 1.2 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.6 KXS15279.1 - 1.7e-15 57.3 0.0 2.8e-15 56.6 0.0 1.3 1 0 0 1 1 1 1 Pleckstrin homology domain DEP PF00610.21 KXS15279.1 - 4.2e-12 45.9 0.0 8.4e-12 45.0 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH_16 PF17838.1 KXS15279.1 - 0.071 13.0 0.1 0.15 11.9 0.1 1.5 1 0 0 1 1 1 0 PH domain MFS_1 PF07690.16 KXS15280.1 - 6.6e-10 38.4 33.1 3.7e-07 29.4 15.0 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily PsbX PF06596.11 KXS15280.1 - 0.05 13.6 2.3 0.05 13.6 2.3 3.0 4 0 0 4 4 4 0 Photosystem II reaction centre X protein (PsbX) COesterase PF00135.28 KXS15281.1 - 1.2e-90 304.8 0.0 2.2e-90 304.0 0.0 1.3 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXS15281.1 - 3.8e-11 43.3 0.4 8.1e-05 22.6 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KXS15281.1 - 0.065 12.7 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family HNH_2 PF13391.6 KXS15282.1 - 9.7e-09 35.2 0.0 1.7e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 HNH endonuclease Symplekin_C PF12295.8 KXS15283.1 - 3.6e-57 193.5 0.6 1.7e-56 191.3 0.1 2.1 1 1 1 2 2 2 1 Symplekin tight junction protein C terminal Acetyltransf_1 PF00583.25 KXS15287.1 - 6.3e-12 45.8 0.0 8.1e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXS15287.1 - 6e-11 42.4 0.0 8.6e-11 41.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXS15287.1 - 1.1e-08 35.4 0.0 1.7e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXS15287.1 - 1.8e-05 24.6 0.0 2.9e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein PanZ PF12568.8 KXS15287.1 - 0.013 15.3 0.1 0.02 14.6 0.1 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_CG PF14542.6 KXS15287.1 - 0.026 14.7 0.0 0.041 14.0 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase DUF4334 PF14232.6 KXS15288.1 - 1.1e-22 79.7 0.5 1.8e-22 79.1 0.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4334) GXWXG PF14231.6 KXS15288.1 - 3.4e-22 78.3 0.5 6.8e-22 77.3 0.5 1.5 1 0 0 1 1 1 1 GXWXG protein Pkinase PF00069.25 KXS15289.1 - 0.11 11.9 0.0 0.45 9.8 0.0 1.8 2 0 0 2 2 2 0 Protein kinase domain Sel1 PF08238.12 KXS15290.1 - 1.2e-12 48.1 27.9 2e-05 25.1 0.6 7.5 8 0 0 8 8 8 5 Sel1 repeat DUF977 PF06163.11 KXS15290.1 - 0.041 13.8 0.1 3.7 7.5 0.0 2.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF977) TPR_2 PF07719.17 KXS15290.1 - 0.057 13.6 9.8 0.46 10.7 0.0 4.9 5 1 0 5 5 5 0 Tetratricopeptide repeat LRR_6 PF13516.6 KXS15290.1 - 0.079 13.0 2.7 0.33 11.1 0.3 2.4 2 0 0 2 2 2 0 Leucine Rich repeat TPR_1 PF00515.28 KXS15290.1 - 0.32 10.9 3.7 8.3 6.4 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 KXS15290.1 - 4.7 7.9 8.5 19 6.0 0.0 3.9 4 1 0 4 4 4 0 Tetratricopeptide repeat Ran_BP1 PF00638.18 KXS15291.1 - 3e-19 69.5 0.0 7.8e-19 68.1 0.0 1.6 2 0 0 2 2 2 1 RanBP1 domain WH1 PF00568.23 KXS15291.1 - 0.0012 18.7 0.0 0.0021 18.0 0.0 1.3 1 0 0 1 1 1 1 WH1 domain F-box PF00646.33 KXS15292.1 - 0.02 14.8 0.4 0.051 13.5 0.4 1.7 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.7 KXS15292.1 - 0.051 13.5 0.2 0.12 12.3 0.2 1.6 1 0 0 1 1 1 0 F-box-like Polysacc_deac_1 PF01522.21 KXS15293.1 - 0.00024 21.0 0.0 0.00039 20.3 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Sulphotransf PF09037.10 KXS15293.1 - 0.02 14.4 0.0 0.032 13.8 0.0 1.2 1 0 0 1 1 1 0 Stf0 sulphotransferase FAM199X PF15814.5 KXS15293.1 - 4.3 6.3 7.8 6.1 5.8 7.8 1.2 1 0 0 1 1 1 0 Protein family FAM199X MFS_1 PF07690.16 KXS15294.1 - 5.5e-08 32.1 8.1 1e-07 31.2 8.1 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily PUCC PF03209.15 KXS15294.1 - 0.018 14.1 0.7 0.018 14.1 0.7 2.0 2 0 0 2 2 2 0 PUCC protein PV-1 PF06637.11 KXS15294.1 - 0.048 12.5 0.1 0.07 11.9 0.1 1.1 1 0 0 1 1 1 0 PV-1 protein (PLVAP) UNC-93 PF05978.16 KXS15294.1 - 0.26 11.0 6.2 0.44 10.2 0.5 2.7 2 1 0 2 2 2 0 Ion channel regulatory protein UNC-93 NAT PF04768.13 KXS15295.1 - 1e-40 139.2 0.0 1.8e-40 138.4 0.0 1.4 1 0 0 1 1 1 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase Acetyltransf_1 PF00583.25 KXS15295.1 - 0.13 12.5 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family zf-MYND PF01753.18 KXS15296.1 - 8e-07 29.0 10.5 1.2e-06 28.5 10.5 1.3 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KXS15296.1 - 0.041 14.2 8.9 0.081 13.2 8.9 1.5 1 1 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding CRAL_TRIO PF00650.20 KXS15297.1 - 1.5e-38 132.0 0.0 2.1e-38 131.5 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KXS15297.1 - 5.3e-07 29.7 0.1 1.4e-06 28.3 0.1 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KXS15297.1 - 8.3e-06 26.0 0.0 1.3e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain SPW PF03779.14 KXS15297.1 - 8.1 6.1 6.4 12 5.6 4.3 2.1 1 1 1 2 2 2 0 SPW repeat DUF1869 PF08956.10 KXS15300.1 - 0.61 10.0 2.0 0.56 10.1 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1869) FUN14 PF04930.15 KXS15301.1 - 0.094 13.1 0.0 0.45 11.0 0.0 2.2 2 0 0 2 2 2 0 FUN14 family DUF4519 PF15012.6 KXS15302.1 - 0.1 12.8 1.3 12 6.2 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) FPN1 PF06963.12 KXS15306.1 - 1.2e-19 70.2 0.5 1.1e-12 47.2 0.5 2.1 2 0 0 2 2 2 2 Ferroportin1 (FPN1) Cpta_toxin PF07254.12 KXS15306.1 - 0.02 14.9 0.2 0.063 13.3 0.1 1.8 2 0 0 2 2 2 0 Membrane-bound toxin component of toxin-antitoxin system WLM PF08325.10 KXS15307.1 - 1.5e-43 149.1 0.1 2.6e-43 148.3 0.1 1.3 1 0 0 1 1 1 1 WLM domain ubiquitin PF00240.23 KXS15307.1 - 6.6e-08 32.2 0.0 2.2e-07 30.5 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin family DUF45 PF01863.17 KXS15307.1 - 0.0083 16.2 0.3 0.017 15.2 0.3 1.6 1 0 0 1 1 1 1 Protein of unknown function DUF45 DHHC PF01529.20 KXS15308.1 - 1.4e-21 77.0 13.8 2.8e-21 76.0 13.8 1.5 1 1 0 1 1 1 1 DHHC palmitoyltransferase Mannosyl_trans3 PF11051.8 KXS15309.1 - 2.5e-43 148.4 0.0 4.3e-43 147.7 0.0 1.4 1 1 0 1 1 1 1 Mannosyltransferase putative Nucleotid_trans PF03407.16 KXS15309.1 - 0.002 18.1 0.0 0.0049 16.9 0.0 1.6 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase SpoIIE PF07228.12 KXS15311.1 - 1.7e-14 54.2 0.4 2.5e-14 53.7 0.4 1.2 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 KXS15311.1 - 4.9e-13 49.3 0.5 1.8e-05 24.5 0.0 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 KXS15311.1 - 2.6e-06 27.2 0.1 3.7e-06 26.7 0.1 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C Ank_2 PF12796.7 KXS15312.1 - 7.1e-19 68.2 2.1 5.9e-09 36.4 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXS15312.1 - 1.2e-17 64.0 4.9 4.5e-07 30.3 0.1 3.3 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXS15312.1 - 1.2e-14 54.1 6.2 4.6e-06 26.8 0.2 4.0 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXS15312.1 - 2.6e-14 51.9 5.1 0.0025 18.2 0.1 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank PF00023.30 KXS15312.1 - 2.5e-12 46.6 6.9 0.0023 18.3 0.0 4.1 3 1 1 4 4 4 4 Ankyrin repeat TFIIB PF00382.19 KXS15312.1 - 0.019 15.0 0.1 0.038 14.1 0.0 1.6 1 1 0 1 1 1 0 Transcription factor TFIIB repeat WD40 PF00400.32 KXS15313.1 - 0.00016 22.4 7.8 0.14 13.1 0.4 5.1 4 2 1 5 5 5 3 WD domain, G-beta repeat PARG_cat PF05028.14 KXS15314.1 - 1.1e-14 54.5 0.0 4.2e-08 32.9 0.0 3.1 2 1 1 3 3 3 3 Poly (ADP-ribose) glycohydrolase (PARG) Oxysterol_BP PF01237.18 KXS15315.1 - 9e-93 311.1 0.0 5.3e-92 308.5 0.0 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein DUF3659 PF12396.8 KXS15315.1 - 0.14 12.1 0.2 0.31 11.0 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3659) Ribosomal_L41 PF05162.13 KXS15315.1 - 9.2 6.4 7.4 17 5.5 7.4 1.4 1 0 0 1 1 1 0 Ribosomal protein L41 Methyltransf_11 PF08241.12 KXS15317.1 - 3.7e-22 78.8 0.0 7.6e-22 77.8 0.0 1.5 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXS15317.1 - 1.8e-18 67.0 0.0 4.9e-18 65.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXS15317.1 - 1.5e-12 47.6 0.0 2.9e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXS15317.1 - 3.3e-11 43.8 0.0 6.9e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXS15317.1 - 8.2e-08 31.9 0.0 1.2e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 KXS15317.1 - 1e-07 31.9 0.0 1.3e-06 28.3 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_8 PF05148.15 KXS15317.1 - 0.00049 20.0 0.0 0.0008 19.3 0.0 1.2 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_29 PF03141.16 KXS15317.1 - 0.0079 14.8 0.0 0.017 13.7 0.0 1.5 2 0 0 2 2 2 1 Putative S-adenosyl-L-methionine-dependent methyltransferase DREV PF05219.12 KXS15317.1 - 0.013 14.6 0.0 0.018 14.2 0.0 1.1 1 0 0 1 1 1 0 DREV methyltransferase CMAS PF02353.20 KXS15317.1 - 0.018 14.4 0.0 0.031 13.6 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase MTS PF05175.14 KXS15317.1 - 0.031 13.8 0.0 0.08 12.5 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_2 PF00891.18 KXS15317.1 - 0.075 12.3 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_4 PF02390.17 KXS15317.1 - 0.11 11.9 0.0 1.6 8.2 0.0 2.1 2 0 0 2 2 2 0 Putative methyltransferase TPMT PF05724.11 KXS15317.1 - 0.14 11.7 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Syndecan PF01034.20 KXS15318.1 - 7e-05 22.7 16.9 0.014 15.3 4.0 2.5 2 0 0 2 2 2 2 Syndecan domain RCR PF12273.8 KXS15318.1 - 8.5e-05 23.2 2.2 0.27 11.9 0.3 2.7 2 0 0 2 2 2 2 Chitin synthesis regulation, resistance to Congo red Amnionless PF14828.6 KXS15318.1 - 0.0024 16.8 1.7 0.73 8.6 0.2 2.3 2 0 0 2 2 2 2 Amnionless Glycophorin_A PF01102.18 KXS15318.1 - 0.0039 17.4 1.6 1 9.6 0.0 2.6 2 0 0 2 2 2 1 Glycophorin A EB PF01683.18 KXS15318.1 - 0.0057 16.9 3.4 0.013 15.8 3.4 1.5 1 0 0 1 1 1 1 EB module Yip1 PF04893.17 KXS15318.1 - 0.0078 16.0 12.5 0.08 12.7 0.6 2.8 2 1 0 2 2 2 2 Yip1 domain Podoplanin PF05808.11 KXS15318.1 - 0.021 14.9 6.2 0.78 9.8 0.2 2.4 2 0 0 2 2 2 0 Podoplanin DUF202 PF02656.15 KXS15318.1 - 0.052 14.0 2.1 2.9 8.4 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF202) UL41A PF17591.2 KXS15318.1 - 0.054 13.6 10.6 1.9 8.6 0.6 2.6 2 0 0 2 2 2 0 Herpesvirus UL41A Cadherin_C_2 PF16492.5 KXS15318.1 - 0.061 14.1 0.3 0.58 10.9 0.0 2.4 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal MtrF PF09472.10 KXS15318.1 - 0.07 12.5 18.4 0.19 11.2 3.6 2.8 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) DUF5326 PF17260.2 KXS15318.1 - 0.2 11.8 17.5 0.52 10.5 2.6 2.7 3 0 0 3 3 2 0 Family of unknown function (DUF5326) DUF2755 PF10954.8 KXS15318.1 - 0.37 10.7 7.5 1.3 9.0 0.2 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2755) EphA2_TM PF14575.6 KXS15318.1 - 0.56 11.1 2.9 13 6.7 0.3 2.6 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Mid2 PF04478.12 KXS15318.1 - 0.77 9.6 5.1 4.8 7.0 0.3 2.3 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor Man-6-P_recep PF02157.15 KXS15318.1 - 0.92 8.5 10.3 1.7 7.7 1.5 2.2 2 0 0 2 2 2 0 Mannose-6-phosphate receptor PRIMA1 PF16101.5 KXS15318.1 - 0.95 9.5 7.4 0.42 10.7 1.6 2.5 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 DoxX PF07681.12 KXS15318.1 - 1 10.0 7.3 0.66 10.6 0.4 3.0 2 0 0 2 2 2 0 DoxX Col_cuticle_N PF01484.17 KXS15318.1 - 1.2 9.2 9.9 2.4 8.3 1.2 3.0 2 0 0 2 2 2 0 Nematode cuticle collagen N-terminal domain DUF2781 PF10914.8 KXS15319.1 - 0.0069 16.8 2.0 0.0088 16.5 0.4 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF2781) DUF1180 PF06679.12 KXS15319.1 - 0.0081 16.6 0.2 0.016 15.6 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1180) DUF2062 PF09835.9 KXS15319.1 - 0.0083 16.0 0.4 0.013 15.4 0.4 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2062) 7tm_6 PF02949.20 KXS15319.1 - 0.24 10.5 4.2 0.36 9.9 4.2 1.2 1 0 0 1 1 1 0 7tm Odorant receptor DUF515 PF04415.12 KXS15319.1 - 3.9 5.7 8.3 5.4 5.3 8.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) LapA_dom PF06305.11 KXS15319.1 - 5.4 6.9 9.3 23 4.9 5.4 2.6 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain TauD PF02668.16 KXS15323.1 - 1.3e-53 182.5 0.1 1.5e-53 182.3 0.1 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family COesterase PF00135.28 KXS15324.1 - 0.004 16.1 0.0 0.0041 16.0 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family COesterase PF00135.28 KXS15325.1 - 5.6e-09 35.4 0.0 7.4e-09 35.0 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXS15325.1 - 2.9e-05 24.1 0.1 4.1e-05 23.5 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KXS15326.1 - 3.6e-13 49.2 0.4 4.2e-13 49.0 0.4 1.0 1 0 0 1 1 1 1 Carboxylesterase family WD40 PF00400.32 KXS15327.1 - 1.2e-18 67.1 5.5 8.6e-05 23.2 0.1 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXS15327.1 - 2.3e-06 27.8 0.0 0.49 10.7 0.0 3.9 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 KXS15327.1 - 6.6e-05 23.3 1.0 0.55 10.8 0.1 4.1 4 1 0 4 4 4 1 PQQ-like domain Nup160 PF11715.8 KXS15327.1 - 0.0028 16.4 0.1 0.023 13.3 0.0 2.0 2 0 0 2 2 2 1 Nucleoporin Nup120/160 VID27 PF08553.10 KXS15327.1 - 0.0048 16.0 0.0 2.1 7.3 0.0 2.2 2 0 0 2 2 2 2 VID27 C-terminal WD40-like domain Coatomer_WDAD PF04053.14 KXS15327.1 - 0.013 14.6 0.0 1.5 7.8 0.0 2.1 2 0 0 2 2 2 0 Coatomer WD associated region PQQ PF01011.21 KXS15327.1 - 0.017 15.1 1.9 0.7 9.9 0.1 3.0 3 0 0 3 3 3 0 PQQ enzyme repeat Cytochrom_D1 PF02239.16 KXS15327.1 - 0.024 13.2 3.7 3 6.3 0.0 3.2 4 0 0 4 4 4 0 Cytochrome D1 heme domain Radical_SAM PF04055.21 KXS15328.1 - 8e-15 55.6 0.0 2e-14 54.3 0.0 1.7 2 0 0 2 2 2 1 Radical SAM superfamily Fer4_14 PF13394.6 KXS15328.1 - 0.00064 19.9 0.0 0.0013 18.9 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_12 PF13353.6 KXS15328.1 - 0.082 13.2 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S single cluster domain YjcB PF15940.5 KXS15328.1 - 0.11 12.6 0.0 0.27 11.5 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function Ribosomal_L19e PF01280.20 KXS15329.1 - 4.8e-56 188.8 8.9 6e-56 188.5 8.9 1.1 1 0 0 1 1 1 1 Ribosomal protein L19e Lant_dehydr_C PF14028.6 KXS15329.1 - 0.00012 21.8 0.1 0.00014 21.5 0.1 1.2 1 0 0 1 1 1 1 Lantibiotic biosynthesis dehydratase C-term EF-hand_7 PF13499.6 KXS15330.1 - 8e-05 23.0 0.1 0.00011 22.6 0.1 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 KXS15330.1 - 0.00011 21.5 0.2 0.00022 20.5 0.2 1.6 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KXS15330.1 - 0.00042 20.0 0.7 0.001 18.8 0.7 1.6 1 0 0 1 1 1 1 EF-hand domain EF-hand_8 PF13833.6 KXS15330.1 - 0.0097 15.7 0.4 0.02 14.7 0.2 1.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_4 PF12763.7 KXS15330.1 - 0.091 12.7 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand RabGAP-TBC PF00566.18 KXS15331.1 - 4.1e-08 33.2 0.3 1.1e-07 31.7 0.1 1.7 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Terminase_3 PF04466.13 KXS15331.1 - 0.12 11.9 0.1 0.19 11.3 0.1 1.2 1 0 0 1 1 1 0 Phage terminase large subunit RabGAP-TBC PF00566.18 KXS15332.1 - 4.3e-19 69.0 0.0 6e-19 68.5 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain NigD_N PF12667.7 KXS15332.1 - 0.027 14.6 0.0 0.045 13.9 0.0 1.3 1 0 0 1 1 1 0 NigD-like N-terminal OB domain Ribosomal_L19e PF01280.20 KXS15333.1 - 7.4e-62 207.7 8.4 7.4e-62 207.7 8.4 1.6 2 0 0 2 2 2 1 Ribosomal protein L19e Lant_dehydr_C PF14028.6 KXS15333.1 - 0.0028 17.2 0.1 0.0041 16.7 0.1 1.4 1 0 0 1 1 1 1 Lantibiotic biosynthesis dehydratase C-term YabA PF06156.13 KXS15333.1 - 0.012 16.3 1.3 3.6 8.3 2.1 2.4 2 0 0 2 2 2 0 Initiation control protein YabA DUF4748 PF15932.5 KXS15334.1 - 5.8e-06 26.0 0.0 7e-06 25.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4748) Ribosomal_L39 PF00832.20 KXS15335.1 - 6.8e-21 73.6 9.9 7.9e-21 73.4 9.9 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein UQ_con PF00179.26 KXS15337.1 - 1.2e-20 73.6 0.1 1.9e-20 72.9 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KXS15337.1 - 0.09 12.5 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B SKIP_SNW PF02731.15 KXS15342.1 - 3.7e-69 231.5 1.5 3.7e-69 231.5 1.5 2.5 2 0 0 2 2 2 1 SKIP/SNW domain Bacteriocin_IIc PF10439.9 KXS15342.1 - 1.1 9.4 4.1 2.1 8.5 4.1 1.4 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Presenilin PF01080.17 KXS15342.1 - 8.2 5.1 9.5 13 4.4 9.5 1.3 1 0 0 1 1 1 0 Presenilin RCC1 PF00415.18 KXS15343.1 - 1.2e-57 192.4 1.7 2.8e-10 40.7 0.1 7.3 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KXS15343.1 - 1.7e-30 104.1 25.3 3.3e-06 26.8 0.0 7.3 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat UPF0561 PF10573.9 KXS15344.1 - 0.19 11.8 3.9 0.34 11.0 0.5 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0561 FXMRP1_C_core PF12235.8 KXS15344.1 - 1.9 9.1 8.6 0.37 11.5 3.4 2.0 1 1 1 2 2 2 0 Fragile X-related 1 protein core C terminal Chromate_transp PF02417.15 KXS15346.1 - 4.9e-58 195.7 38.0 1.2e-29 103.5 18.2 2.2 2 0 0 2 2 2 2 Chromate transporter ThiJ_like PF17124.5 KXS15347.1 - 9.1e-55 185.4 0.0 1.1e-54 185.1 0.0 1.1 1 0 0 1 1 1 1 ThiJ/PfpI family-like DJ-1_PfpI PF01965.24 KXS15347.1 - 4.5e-09 36.3 0.0 1.2e-08 35.0 0.0 1.7 2 1 0 2 2 2 1 DJ-1/PfpI family GATase_3 PF07685.14 KXS15347.1 - 0.024 14.2 0.0 0.035 13.7 0.0 1.2 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain SNO PF01174.19 KXS15347.1 - 0.045 13.6 0.0 0.08 12.8 0.0 1.3 1 0 0 1 1 1 0 SNO glutamine amidotransferase family UPF0113_N PF17833.1 KXS15348.1 - 1.3e-24 86.6 0.2 1.7e-24 86.1 0.2 1.2 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 KXS15348.1 - 0.0005 20.3 0.0 0.00099 19.3 0.0 1.5 1 0 0 1 1 1 1 UPF0113 PUA domain UvrB_inter PF17757.1 KXS15348.1 - 0.058 13.6 0.0 0.14 12.4 0.0 1.5 2 0 0 2 2 2 0 UvrB interaction domain DUF5410 PF17422.2 KXS15348.1 - 0.1 11.8 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5410) MFS_1 PF07690.16 KXS15349.1 - 7.8e-43 146.7 41.8 7.8e-43 146.7 41.8 1.5 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 KXS15349.1 - 0.028 13.3 14.0 0.7 8.7 0.3 3.5 2 1 0 3 3 3 0 MFS_1 like family Globin PF00042.22 KXS15350.1 - 0.00034 21.2 0.1 0.0026 18.3 0.1 2.2 1 1 0 1 1 1 1 Globin HMw1_D2 PF18254.1 KXS15350.1 - 0.092 13.1 0.0 0.2 12.0 0.0 1.5 1 0 0 1 1 1 0 HMW1 domain 2 TFIIA PF03153.13 KXS15351.1 - 0.061 13.3 1.2 0.08 12.9 1.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Fungal_trans PF04082.18 KXS15352.1 - 4.4e-14 52.1 2.0 8.6e-13 47.9 0.6 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Tropomyosin PF00261.20 KXS15353.1 - 0.00081 18.8 1.9 0.0016 17.9 1.9 1.4 1 0 0 1 1 1 1 Tropomyosin CENP-H PF05837.12 KXS15353.1 - 0.0049 17.3 4.0 0.0092 16.4 4.0 1.4 1 0 0 1 1 1 1 Centromere protein H (CENP-H) Nup54 PF13874.6 KXS15353.1 - 0.012 15.7 0.2 0.021 14.9 0.2 1.4 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 TMF_DNA_bd PF12329.8 KXS15353.1 - 0.016 15.2 5.3 0.13 12.3 2.0 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding GAS PF13851.6 KXS15353.1 - 0.019 14.3 0.5 0.033 13.5 0.5 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Tropomyosin_1 PF12718.7 KXS15353.1 - 0.023 14.9 2.7 0.048 13.8 2.7 1.5 1 0 0 1 1 1 0 Tropomyosin like DUF724 PF05266.14 KXS15353.1 - 0.034 14.0 0.7 0.056 13.3 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) KLRAQ PF10205.9 KXS15353.1 - 0.072 13.3 0.6 0.13 12.5 0.6 1.4 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein FlaC_arch PF05377.11 KXS15353.1 - 0.19 12.1 2.2 0.31 11.5 1.2 1.8 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) ATG16 PF08614.11 KXS15353.1 - 0.23 11.7 7.7 0.25 11.6 6.9 1.3 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) DivIC PF04977.15 KXS15353.1 - 0.39 10.5 2.5 7.5 6.4 0.2 2.3 1 1 1 2 2 2 0 Septum formation initiator zf-C3HC4 PF00097.25 KXS15354.1 - 1.2e-08 34.7 10.8 2e-08 34.0 10.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXS15354.1 - 5.4e-08 32.5 13.2 9.4e-08 31.8 13.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KXS15354.1 - 7.9e-08 32.0 10.2 1.4e-07 31.3 10.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FHA PF00498.26 KXS15354.1 - 5.5e-07 29.8 0.0 1.9e-06 28.1 0.0 2.0 1 0 0 1 1 1 1 FHA domain zf-RING_2 PF13639.6 KXS15354.1 - 8.6e-06 26.0 14.1 8.6e-06 26.0 14.1 1.7 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 KXS15354.1 - 0.00063 19.7 12.4 0.0013 18.7 12.4 1.5 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KXS15354.1 - 0.0014 18.5 10.3 0.0025 17.6 10.3 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KXS15354.1 - 0.0039 17.1 9.6 0.0067 16.4 9.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KXS15354.1 - 0.0072 16.5 13.2 0.013 15.6 13.2 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 KXS15354.1 - 0.008 16.4 12.0 0.021 15.1 12.0 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_4 PF14570.6 KXS15354.1 - 0.16 11.8 4.2 0.31 10.9 4.2 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_10 PF16685.5 KXS15354.1 - 3.3 7.9 5.4 6 7.1 5.4 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 Ank_4 PF13637.6 KXS15355.1 - 6.2e-05 23.5 0.0 2.6 8.7 0.0 3.7 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 KXS15355.1 - 0.00026 21.3 0.1 0.69 10.5 0.1 3.6 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.7 KXS15355.1 - 0.00048 20.7 0.0 0.14 12.7 0.0 3.2 2 2 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXS15355.1 - 0.0015 18.9 0.0 0.34 11.6 0.0 3.4 4 0 0 4 4 4 1 Ankyrin repeat Pkinase_Tyr PF07714.17 KXS15356.1 - 2.8e-18 66.1 0.0 3e-18 66.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXS15356.1 - 1.9e-17 63.5 0.0 2e-17 63.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 KXS15356.1 - 0.0019 17.8 0.0 0.002 17.8 0.0 1.1 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 KXS15356.1 - 0.007 15.7 0.0 0.0078 15.6 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXS15356.1 - 0.0096 15.9 0.0 0.011 15.7 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KXS15356.1 - 0.027 14.1 0.0 5.7 6.5 0.0 2.0 1 1 1 2 2 2 0 Choline/ethanolamine kinase Pkinase PF00069.25 KXS15357.1 - 1.7e-37 129.3 0.0 7.8e-24 84.5 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXS15357.1 - 1.2e-17 64.0 0.0 1.5e-12 47.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KXS15357.1 - 0.00037 20.5 0.5 0.38 10.6 0.1 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family zf-RING_2 PF13639.6 KXS15358.1 - 1e-14 54.5 5.0 1.5e-14 54.0 5.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KXS15358.1 - 8.4e-11 41.5 4.6 1.4e-10 40.9 4.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KXS15358.1 - 9.1e-11 41.3 1.3 1.9e-10 40.3 1.3 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 KXS15358.1 - 4.6e-09 36.0 2.4 6.9e-09 35.4 2.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXS15358.1 - 8.1e-08 32.2 2.1 2.5e-07 30.6 2.2 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 KXS15358.1 - 9.2e-07 29.1 8.5 2.8e-06 27.5 8.5 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 KXS15358.1 - 1.5e-06 28.0 1.9 2.1e-06 27.5 1.9 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KXS15358.1 - 6.3e-06 26.3 3.2 1.1e-05 25.4 3.2 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 KXS15358.1 - 7.1e-06 25.9 2.6 1.1e-05 25.3 2.6 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 KXS15358.1 - 0.00042 20.3 3.5 0.0012 18.8 3.5 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 KXS15358.1 - 0.0011 18.6 1.9 0.0021 17.7 1.9 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 KXS15358.1 - 0.0019 18.0 1.8 0.0032 17.2 1.8 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING-like PF08746.11 KXS15358.1 - 0.0019 18.5 2.7 0.0031 17.8 2.7 1.3 1 0 0 1 1 1 1 RING-like domain Prok-RING_4 PF14447.6 KXS15358.1 - 0.0054 16.6 7.0 0.099 12.5 7.2 2.2 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-HC5HC2H_2 PF13832.6 KXS15358.1 - 0.14 12.3 0.2 0.23 11.6 0.2 1.3 1 0 0 1 1 1 0 PHD-zinc-finger like domain RINGv PF12906.7 KXS15358.1 - 0.22 11.7 2.6 0.45 10.7 2.6 1.6 1 1 0 1 1 1 0 RING-variant domain FANCL_C PF11793.8 KXS15358.1 - 0.29 11.3 4.3 2.7 8.2 4.3 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_2 PF13639.6 KXS15359.1 - 1.6e-13 50.8 5.6 2.3e-13 50.3 5.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KXS15359.1 - 6.9e-10 38.5 2.2 6.9e-10 38.5 2.2 1.6 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KXS15359.1 - 1.8e-08 34.1 4.6 2.6e-08 33.5 4.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXS15359.1 - 4.4e-08 32.9 2.3 6.5e-08 32.3 2.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KXS15359.1 - 1.4e-07 31.7 7.7 6e-07 29.7 7.7 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KXS15359.1 - 2.5e-06 27.3 2.2 3.7e-06 26.8 2.2 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KXS15359.1 - 4e-06 26.7 6.3 1.1e-05 25.3 6.4 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 KXS15359.1 - 9.7e-05 22.4 5.5 0.00014 21.8 5.5 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 KXS15359.1 - 0.00098 18.9 4.9 0.0032 17.3 4.9 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KXS15359.1 - 0.0058 16.8 3.5 0.015 15.4 3.5 1.7 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING Zn_ribbon_17 PF17120.5 KXS15359.1 - 0.022 14.3 5.7 0.032 13.8 5.7 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 KXS15359.1 - 0.029 14.2 2.5 0.029 14.2 2.5 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 KXS15359.1 - 0.081 12.7 3.2 0.25 11.1 3.0 1.8 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 KXS15359.1 - 0.26 11.5 7.5 3.5 7.9 7.5 2.5 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.7 KXS15359.1 - 0.27 11.4 3.6 0.78 9.9 3.5 1.8 1 1 1 2 2 2 0 RING-variant domain Rad50_zn_hook PF04423.14 KXS15359.1 - 0.34 10.8 1.9 4.8 7.1 0.2 2.1 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-RING-like PF08746.11 KXS15359.1 - 0.75 10.2 7.3 0.28 11.5 0.7 2.1 2 0 0 2 2 2 0 RING-like domain Aminotran_3 PF00202.21 KXS15360.1 - 2.1e-113 379.1 0.0 3.1e-113 378.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 KXS15360.1 - 0.11 11.6 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II Laminin_G_3 PF13385.6 KXS15361.1 - 6e-08 33.0 0.0 1.4e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily ZapB PF06005.12 KXS15361.1 - 9e-08 32.5 15.6 0.056 13.9 3.2 4.6 3 1 1 4 4 4 3 Cell division protein ZapB KASH_CCD PF14662.6 KXS15361.1 - 1.5e-07 31.4 15.7 7.8e-05 22.6 6.6 2.6 1 1 1 2 2 2 2 Coiled-coil region of CCDC155 or KASH Metallophos PF00149.28 KXS15361.1 - 1.4e-05 25.7 0.0 0.00021 21.9 0.0 2.3 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase TSC22 PF01166.18 KXS15361.1 - 2.2e-05 24.6 15.6 1.2 9.5 0.0 6.2 4 2 2 6 6 6 1 TSC-22/dip/bun family YabA PF06156.13 KXS15361.1 - 2.5e-05 24.8 14.6 0.023 15.3 1.2 4.5 1 1 3 4 4 4 2 Initiation control protein YabA DivIC PF04977.15 KXS15361.1 - 4.3e-05 23.2 25.1 0.01 15.6 1.3 5.5 3 2 2 5 5 5 2 Septum formation initiator Shugoshin_N PF07558.11 KXS15361.1 - 0.0003 20.6 22.5 0.033 14.0 2.2 6.0 4 2 2 6 6 6 3 Shugoshin N-terminal coiled-coil region CENP-F_leu_zip PF10473.9 KXS15361.1 - 0.00041 20.4 17.1 0.006 16.6 3.4 3.0 2 1 1 3 3 3 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 bZIP_1 PF00170.21 KXS15361.1 - 0.00084 19.4 18.0 0.15 12.2 3.0 5.6 4 2 1 5 5 5 1 bZIP transcription factor APG6_N PF17675.1 KXS15361.1 - 0.002 18.6 18.0 0.25 11.9 2.1 3.5 2 1 1 3 3 3 2 Apg6 coiled-coil region DUF2046 PF09755.9 KXS15361.1 - 0.0054 16.0 11.9 0.19 10.9 7.4 3.0 1 1 1 2 2 2 1 Uncharacterized conserved protein H4 (DUF2046) Laminin_G_2 PF02210.24 KXS15361.1 - 0.0095 16.5 0.0 0.043 14.4 0.0 2.1 1 0 0 1 1 1 1 Laminin G domain DUF2353 PF09789.9 KXS15361.1 - 0.013 14.8 18.3 0.017 14.5 8.9 2.7 1 1 1 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) CENP-H PF05837.12 KXS15361.1 - 0.016 15.6 0.9 0.016 15.6 0.9 4.3 1 1 3 4 4 4 0 Centromere protein H (CENP-H) Ank_3 PF13606.6 KXS15361.1 - 0.017 15.6 0.1 0.98 10.2 0.1 3.4 3 0 0 3 3 2 0 Ankyrin repeat HMMR_C PF15908.5 KXS15361.1 - 0.025 14.8 14.5 0.77 10.0 0.7 4.5 3 1 2 5 5 4 0 Hyaluronan mediated motility receptor C-terminal ATG16 PF08614.11 KXS15361.1 - 0.034 14.4 33.5 1.4 9.1 1.8 3.3 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) HALZ PF02183.18 KXS15361.1 - 0.047 13.9 16.0 0.9 9.8 0.6 5.9 4 2 2 7 7 6 0 Homeobox associated leucine zipper GIT_CC PF16559.5 KXS15361.1 - 0.054 13.4 17.8 0.57 10.1 0.8 5.4 4 2 1 5 5 5 0 GIT coiled-coil Rho guanine nucleotide exchange factor JIP_LZII PF16471.5 KXS15361.1 - 0.1 12.8 13.4 6.5 7.0 0.7 4.4 2 1 0 3 3 3 0 JNK-interacting protein leucine zipper II Filament PF00038.21 KXS15361.1 - 0.11 12.0 21.3 1.5 8.3 14.7 3.1 2 1 0 2 2 2 0 Intermediate filament protein UPF0449 PF15136.6 KXS15361.1 - 0.13 12.7 12.2 0.56 10.7 7.5 3.6 3 1 0 3 3 2 0 Uncharacterised protein family UPF0449 Ank_2 PF12796.7 KXS15361.1 - 0.15 12.6 0.0 7.1 7.3 0.0 3.2 2 1 0 2 2 1 0 Ankyrin repeats (3 copies) DUF4972 PF16342.5 KXS15361.1 - 0.16 11.7 0.1 0.49 10.1 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4972) Cnn_1N PF07989.11 KXS15361.1 - 0.33 11.1 16.7 0.44 10.7 0.9 4.3 3 1 2 5 5 4 0 Centrosomin N-terminal motif 1 bZIP_2 PF07716.15 KXS15361.1 - 0.36 11.0 22.2 1.2 9.3 0.9 5.7 5 1 1 6 6 6 0 Basic region leucine zipper DUF4686 PF15742.5 KXS15361.1 - 0.4 9.8 13.6 1.2 8.2 11.7 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4686) DUF4201 PF13870.6 KXS15361.1 - 0.5 10.1 13.8 7.6 6.2 1.6 4.2 2 2 2 5 5 4 0 Domain of unknown function (DUF4201) Rootletin PF15035.6 KXS15361.1 - 0.57 10.2 24.3 3.4 7.6 5.8 3.6 2 1 1 3 3 3 0 Ciliary rootlet component, centrosome cohesion DUF724 PF05266.14 KXS15361.1 - 0.97 9.2 13.6 6 6.6 2.1 3.4 2 1 2 4 4 4 0 Protein of unknown function (DUF724) BRE1 PF08647.11 KXS15361.1 - 1.2 9.2 11.5 6.2 7.0 0.2 3.4 2 1 2 4 4 3 0 BRE1 E3 ubiquitin ligase Macoilin PF09726.9 KXS15361.1 - 1.3 7.4 25.6 1.9 6.9 3.1 2.0 1 1 1 2 2 2 0 Macoilin family BLOC1_2 PF10046.9 KXS15361.1 - 1.6 9.0 5.4 24 5.3 0.3 3.4 2 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1664 PF07889.12 KXS15361.1 - 1.7 8.7 6.1 12 6.0 0.1 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) ADIP PF11559.8 KXS15361.1 - 2 8.5 25.4 0.37 10.9 3.6 3.8 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding HAP1_N PF04849.13 KXS15361.1 - 2 7.5 17.8 1.7 7.8 14.3 2.7 2 1 0 2 2 2 0 HAP1 N-terminal conserved region FlxA PF14282.6 KXS15361.1 - 2.9 7.9 6.5 0.82 9.7 0.6 2.5 2 1 0 2 2 2 0 FlxA-like protein TMF_DNA_bd PF12329.8 KXS15361.1 - 3.1 7.8 15.2 3.3 7.8 1.6 4.2 2 1 3 5 5 4 0 TATA element modulatory factor 1 DNA binding Fez1 PF06818.15 KXS15361.1 - 3.3 8.1 23.1 1.1 9.6 9.1 3.1 1 1 0 2 2 2 0 Fez1 Leu_zip PF15294.6 KXS15361.1 - 3.6 7.0 15.0 8.7 5.8 1.6 2.5 1 1 0 2 2 2 0 Leucine zipper Atg14 PF10186.9 KXS15361.1 - 4.6 6.2 26.3 1.3 8.0 11.0 3.1 1 1 1 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 FlaC_arch PF05377.11 KXS15361.1 - 4.8 7.6 5.4 22 5.6 0.3 3.3 3 0 0 3 3 2 0 Flagella accessory protein C (FlaC) TMF_TATA_bd PF12325.8 KXS15361.1 - 5.7 7.2 22.9 3.4 7.9 2.3 4.3 3 1 1 4 4 4 0 TATA element modulatory factor 1 TATA binding APC_N_CC PF16689.5 KXS15361.1 - 6.3 6.9 17.5 0.58 10.3 0.9 5.0 4 1 1 5 5 5 0 Coiled-coil N-terminus of APC, dimerisation domain Uso1_p115_C PF04871.13 KXS15361.1 - 6.7 7.1 20.1 0.3 11.5 8.2 3.1 2 1 1 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region GAS PF13851.6 KXS15361.1 - 7.9 5.8 17.8 3.1 7.1 7.2 3.4 2 1 2 4 4 4 0 Growth-arrest specific micro-tubule binding NRBF2 PF08961.10 KXS15361.1 - 8.7 5.9 21.4 2.4 7.7 2.9 4.7 2 2 3 6 6 6 0 Nuclear receptor-binding factor 2, autophagy regulator CASP_C PF08172.12 KXS15361.1 - 9 5.5 16.9 0.9 8.8 2.1 3.6 1 1 1 2 2 2 0 CASP C terminal MFS_1 PF07690.16 KXS15362.1 - 1.2e-16 60.6 56.6 2.6e-11 43.0 23.0 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily SH3_9 PF14604.6 KXS15363.1 - 1.1e-06 28.4 0.0 1.5e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXS15363.1 - 0.0034 17.0 0.0 0.005 16.4 0.0 1.3 1 0 0 1 1 1 1 SH3 domain TSC22 PF01166.18 KXS15366.1 - 0.00034 20.9 1.2 0.1 12.9 0.1 2.3 1 1 1 2 2 2 2 TSC-22/dip/bun family YabA PF06156.13 KXS15366.1 - 0.00071 20.2 0.4 0.0039 17.8 0.1 1.8 1 1 1 2 2 2 2 Initiation control protein YabA HALZ PF02183.18 KXS15366.1 - 0.00074 19.7 4.2 0.34 11.2 1.3 2.7 1 1 2 3 3 3 2 Homeobox associated leucine zipper bZIP_1 PF00170.21 KXS15366.1 - 0.002 18.2 2.8 0.013 15.6 0.9 2.1 1 1 1 2 2 2 1 bZIP transcription factor KASH_CCD PF14662.6 KXS15366.1 - 0.0082 16.0 3.6 0.013 15.3 1.1 1.7 1 1 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH Shugoshin_N PF07558.11 KXS15366.1 - 0.011 15.6 3.4 2.3 8.2 1.2 2.9 1 1 1 2 2 2 0 Shugoshin N-terminal coiled-coil region DivIC PF04977.15 KXS15366.1 - 0.019 14.7 1.8 0.3 10.9 1.6 2.1 1 1 1 2 2 2 0 Septum formation initiator DUF2353 PF09789.9 KXS15366.1 - 0.025 14.0 0.3 0.027 13.8 0.3 1.0 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) ZapB PF06005.12 KXS15366.1 - 0.026 15.0 2.1 0.097 13.1 2.1 1.8 1 1 0 1 1 1 0 Cell division protein ZapB TMF_TATA_bd PF12325.8 KXS15366.1 - 0.04 14.1 1.4 0.048 13.9 1.4 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding TMCO5 PF14992.6 KXS15366.1 - 0.041 13.5 0.7 0.045 13.3 0.7 1.1 1 0 0 1 1 1 0 TMCO5 family DUF4201 PF13870.6 KXS15366.1 - 0.052 13.3 0.6 0.057 13.1 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) bZIP_2 PF07716.15 KXS15366.1 - 0.077 13.1 5.8 3.8 7.7 3.8 2.8 1 1 1 2 2 2 0 Basic region leucine zipper GIT_CC PF16559.5 KXS15366.1 - 0.1 12.5 5.2 0.93 9.4 0.7 2.2 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor CENP-H PF05837.12 KXS15366.1 - 0.24 11.8 4.2 0.48 10.9 4.2 1.6 1 1 0 1 1 1 0 Centromere protein H (CENP-H) CASP_C PF08172.12 KXS15366.1 - 0.24 10.7 1.8 0.73 9.1 1.1 1.5 1 1 1 2 2 2 0 CASP C terminal Rootletin PF15035.6 KXS15366.1 - 0.3 11.1 5.8 0.44 10.5 3.3 1.8 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion Ank_4 PF13637.6 KXS15368.1 - 9.5e-07 29.3 0.0 0.087 13.4 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXS15368.1 - 0.00031 21.0 0.1 0.62 10.4 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXS15368.1 - 0.00047 20.4 0.1 0.18 12.4 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.7 KXS15368.1 - 0.00077 20.0 0.0 5 7.8 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) MPLKIP PF15502.6 KXS15369.1 - 0.00013 22.1 0.5 0.00077 19.6 0.0 2.6 2 0 0 2 2 2 1 M-phase-specific PLK1-interacting protein Ank_4 PF13637.6 KXS15370.1 - 0.069 13.8 0.0 1.1e+02 3.6 0.0 3.3 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXS15372.1 - 0.00043 20.8 0.0 0.75 10.4 0.0 3.2 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXS15372.1 - 0.00064 20.3 0.2 8.7 7.0 0.0 3.3 3 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXS15372.1 - 0.0029 18.0 0.0 1.2 10.0 0.0 3.6 3 0 0 3 3 3 1 Ankyrin repeat DUF3287 PF11690.8 KXS15372.1 - 0.003 17.3 0.3 0.0053 16.5 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3287) Ank_2 PF12796.7 KXS15373.1 - 1.1e-20 74.0 2.8 7.1e-13 49.0 0.8 3.1 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXS15373.1 - 1.2e-15 56.0 6.1 0.016 15.7 0.2 5.8 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.6 KXS15373.1 - 4.3e-15 55.9 2.5 0.0011 19.5 0.0 4.7 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXS15373.1 - 5e-14 52.2 5.6 0.00052 20.3 0.1 4.5 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 KXS15373.1 - 3.8e-12 46.1 9.4 0.12 12.8 0.4 5.3 4 1 1 5 5 5 5 Ankyrin repeat Tropomyosin_1 PF12718.7 KXS15374.1 - 0.0041 17.3 0.2 0.0053 16.9 0.2 1.1 1 0 0 1 1 1 1 Tropomyosin like TSC22 PF01166.18 KXS15374.1 - 0.0047 17.2 0.2 0.37 11.1 0.0 2.1 1 1 1 2 2 2 1 TSC-22/dip/bun family CENP-F_leu_zip PF10473.9 KXS15374.1 - 0.017 15.2 0.5 0.021 14.8 0.5 1.1 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4618 PF15397.6 KXS15374.1 - 0.023 14.1 0.0 0.027 13.9 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) TMF_TATA_bd PF12325.8 KXS15374.1 - 0.025 14.8 0.4 0.03 14.5 0.4 1.1 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding ADIP PF11559.8 KXS15374.1 - 0.033 14.3 1.0 0.043 13.9 1.0 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding FlaC_arch PF05377.11 KXS15374.1 - 0.037 14.4 0.1 0.055 13.9 0.1 1.2 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) EMP24_GP25L PF01105.24 KXS15374.1 - 0.041 13.8 0.0 0.048 13.6 0.0 1.1 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD YabA PF06156.13 KXS15374.1 - 0.044 14.4 0.1 0.063 13.9 0.1 1.2 1 0 0 1 1 1 0 Initiation control protein YabA Sipho_Gp157 PF05565.11 KXS15374.1 - 0.06 13.4 0.3 0.076 13.0 0.3 1.1 1 0 0 1 1 1 0 Siphovirus Gp157 bZIP_1 PF00170.21 KXS15374.1 - 0.067 13.3 0.5 0.13 12.4 0.5 1.5 1 1 0 1 1 1 0 bZIP transcription factor Prefoldin_2 PF01920.20 KXS15374.1 - 0.087 12.8 0.0 0.11 12.5 0.0 1.1 1 0 0 1 1 1 0 Prefoldin subunit LPP PF04728.13 KXS15374.1 - 0.094 13.1 0.6 0.15 12.5 0.6 1.3 1 0 0 1 1 1 0 Lipoprotein leucine-zipper HALZ PF02183.18 KXS15374.1 - 0.11 12.8 0.6 2.3 8.5 0.7 2.1 1 1 1 2 2 2 0 Homeobox associated leucine zipper DivIC PF04977.15 KXS15374.1 - 0.11 12.3 1.2 7.9 6.3 0.1 2.0 1 1 1 2 2 2 0 Septum formation initiator HMMR_C PF15908.5 KXS15374.1 - 0.11 12.7 0.1 0.14 12.4 0.1 1.1 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor C-terminal DUF4988 PF16378.5 KXS15374.1 - 0.12 12.1 0.1 0.16 11.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function bZIP_2 PF07716.15 KXS15374.1 - 0.31 11.2 1.7 11 6.2 0.2 2.1 1 1 1 2 2 2 0 Basic region leucine zipper Metallophos PF00149.28 KXS15376.1 - 0.0011 19.6 0.2 0.0014 19.2 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF4768 PF15989.5 KXS15376.1 - 0.052 13.5 0.1 0.07 13.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4768) FMO-like PF00743.19 KXS15379.1 - 7e-18 64.3 0.4 9e-16 57.4 0.2 3.2 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KXS15379.1 - 2.3e-10 40.6 0.0 8.2e-09 35.6 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KXS15379.1 - 1.1e-08 34.7 0.0 7.5e-05 22.1 0.0 2.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXS15379.1 - 2.9e-06 27.4 0.1 0.022 14.7 0.0 3.2 2 1 0 2 2 2 2 FAD-NAD(P)-binding K_oxygenase PF13434.6 KXS15379.1 - 2e-05 23.9 0.1 0.035 13.3 0.0 3.2 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KXS15379.1 - 0.00018 20.9 0.0 0.11 11.7 0.0 3.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXS15379.1 - 0.00027 20.2 0.1 0.021 14.1 0.1 2.2 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 KXS15379.1 - 0.0098 15.5 0.3 0.22 11.1 0.1 2.9 2 1 0 2 2 2 1 FAD dependent oxidoreductase PALP PF00291.25 KXS15380.1 - 2e-76 257.2 2.2 2.6e-76 256.8 2.2 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 KXS15380.1 - 1.8e-36 123.8 0.0 5.2e-19 67.8 0.0 2.3 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase Flavi_NS4B PF01349.17 KXS15381.1 - 0.074 12.4 0.1 0.13 11.7 0.1 1.3 1 0 0 1 1 1 0 Flavivirus non-structural protein NS4B Fungal_trans PF04082.18 KXS15382.1 - 5.8e-26 91.1 0.0 8.2e-26 90.6 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain RrnaAD PF00398.20 KXS15384.1 - 2e-55 187.7 0.0 2.6e-55 187.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 KXS15384.1 - 2e-09 38.1 0.0 4e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXS15384.1 - 6.6e-07 29.9 0.0 2.7e-06 27.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.19 KXS15384.1 - 3.4e-06 27.0 0.0 6.3e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.12 KXS15384.1 - 1.9e-05 25.3 0.0 5.8e-05 23.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXS15384.1 - 0.00081 19.2 0.0 0.0013 18.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXS15384.1 - 0.0023 17.8 0.0 0.0048 16.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXS15384.1 - 0.0093 15.3 0.0 0.015 14.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KXS15384.1 - 0.0097 15.5 0.0 0.018 14.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.7 KXS15384.1 - 0.012 15.6 0.0 0.52 10.2 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain CMAS PF02353.20 KXS15384.1 - 0.019 14.3 0.0 0.029 13.6 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase DREV PF05219.12 KXS15384.1 - 0.02 14.0 0.0 0.032 13.3 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase NodS PF05401.11 KXS15384.1 - 0.026 14.2 0.0 0.051 13.2 0.0 1.4 1 0 0 1 1 1 0 Nodulation protein S (NodS) Met_10 PF02475.16 KXS15384.1 - 0.033 13.9 0.0 0.053 13.3 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein PRMT5 PF05185.16 KXS15384.1 - 0.1 12.4 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Methyltransf_28 PF02636.17 KXS15384.1 - 0.12 12.0 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_2 PF00891.18 KXS15384.1 - 0.15 11.4 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain PrmA PF06325.13 KXS15384.1 - 0.17 11.2 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Ribosomal_S2 PF00318.20 KXS15385.1 - 7.8e-28 97.2 0.2 8.7e-14 51.3 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 KXS15385.1 - 0.00037 21.8 15.4 0.0012 20.1 15.4 2.0 1 1 0 1 1 1 1 40S ribosomal protein SA C-terminus dsrm PF00035.26 KXS15386.1 - 0.045 14.5 0.1 0.11 13.2 0.1 1.7 1 0 0 1 1 1 0 Double-stranded RNA binding motif Lipase_3 PF01764.25 KXS15387.1 - 0.00017 21.5 0.0 0.00032 20.6 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_1 PF00561.20 KXS15387.1 - 0.012 15.3 0.0 0.029 14.0 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXS15387.1 - 0.024 13.9 0.0 0.04 13.2 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 UPF0227 PF05728.12 KXS15387.1 - 0.059 13.3 0.0 0.096 12.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Fzo_mitofusin PF04799.13 KXS15387.1 - 0.35 10.4 0.7 0.59 9.7 0.7 1.2 1 0 0 1 1 1 0 fzo-like conserved region HATPase_c PF02518.26 KXS15388.1 - 1.2e-29 103.1 0.0 2.7e-29 102.0 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KXS15388.1 - 1.3e-20 73.2 0.6 2.9e-19 68.8 0.1 2.8 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain Response_reg PF00072.24 KXS15388.1 - 1.2e-15 57.7 0.2 1.9e-15 57.0 0.2 1.4 1 0 0 1 1 1 1 Response regulator receiver domain Prim-Pol PF09250.11 KXS15389.1 - 0.018 15.4 0.0 4.7 7.6 0.0 2.3 2 0 0 2 2 2 0 Bifunctional DNA primase/polymerase, N-terminal D5_N PF08706.11 KXS15390.1 - 3.3e-05 24.2 0.1 9e-05 22.8 0.1 1.8 1 0 0 1 1 1 1 D5 N terminal like DUF2451 PF10474.9 KXS15392.1 - 0.016 15.0 0.0 0.021 14.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2451) AntA PF08346.12 KXS15394.1 - 0.036 14.6 0.0 0.12 12.9 0.0 1.9 2 0 0 2 2 2 0 AntA/AntB antirepressor 4HBT_3 PF13622.6 KXS15395.1 - 2e-30 106.8 0.2 3.1e-30 106.3 0.2 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 KXS15395.1 - 0.0047 17.2 0.2 0.27 11.6 0.0 2.4 2 0 0 2 2 2 1 Thioesterase superfamily AdoHcyase PF05221.17 KXS15396.1 - 2.2e-136 453.9 0.0 8.3e-72 241.8 0.3 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 KXS15396.1 - 1.5e-85 285.3 3.7 2.1e-85 284.7 3.7 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 KXS15396.1 - 5.6e-09 35.6 0.4 1.5e-08 34.2 0.3 1.6 1 1 1 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 KXS15396.1 - 5.5e-05 22.8 0.2 9e-05 22.1 0.2 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 KXS15396.1 - 0.0041 17.4 0.5 0.022 15.0 0.3 2.2 2 0 0 2 2 2 1 TrkA-N domain tRNA_anti_2 PF13742.6 KXS15396.1 - 0.025 14.8 0.0 0.23 11.7 0.0 2.2 2 0 0 2 2 2 0 OB-fold nucleic acid binding domain Thioredoxin_8 PF13905.6 KXS15397.1 - 8.5e-22 77.3 0.0 1.2e-21 76.8 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.20 KXS15397.1 - 7.1e-10 38.8 0.0 8.4e-08 32.1 0.0 2.2 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.6 KXS15397.1 - 7.5e-07 29.6 0.0 2e-06 28.2 0.0 1.7 2 0 0 2 2 2 1 Thioredoxin-like domain TraF PF13728.6 KXS15397.1 - 1.9e-06 27.8 0.0 3.5e-06 27.0 0.0 1.4 1 1 0 1 1 1 1 F plasmid transfer operon protein Redoxin PF08534.10 KXS15397.1 - 6.7e-06 25.9 0.0 1.2e-05 25.1 0.0 1.5 1 1 0 1 1 1 1 Redoxin DUF953 PF06110.11 KXS15397.1 - 2.5e-05 23.9 0.1 0.00035 20.2 0.1 2.2 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) AhpC-TSA PF00578.21 KXS15397.1 - 3.6e-05 23.7 0.0 5.5e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_9 PF14595.6 KXS15397.1 - 0.00011 22.0 0.0 0.0004 20.1 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 KXS15397.1 - 0.0026 17.9 0.0 0.0061 16.7 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin-like Glutaredoxin PF00462.24 KXS15397.1 - 0.0064 16.7 0.2 0.023 14.9 0.2 2.0 1 1 0 1 1 1 1 Glutaredoxin DSBA PF01323.20 KXS15397.1 - 0.24 11.2 0.7 3.5 7.4 0.2 2.1 1 1 1 2 2 2 0 DSBA-like thioredoxin domain Ferric_reduct PF01794.19 KXS15398.1 - 6.8e-08 32.7 3.3 6.8e-08 32.7 3.3 2.2 1 1 1 2 2 2 1 Ferric reductase like transmembrane component SWIRM PF04433.17 KXS15400.1 - 5.7e-05 23.4 0.0 0.00012 22.4 0.0 1.4 1 0 0 1 1 1 1 SWIRM domain Ank_2 PF12796.7 KXS15402.1 - 2.3e-06 28.1 0.1 0.00067 20.2 0.0 3.0 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXS15402.1 - 1.7e-05 24.8 0.3 0.0054 17.1 0.0 3.5 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 KXS15402.1 - 1.7e-05 25.2 0.1 0.2 12.3 0.0 3.6 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 KXS15402.1 - 0.00041 20.7 0.3 0.37 11.3 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeat HALZ PF02183.18 KXS15402.1 - 0.0013 18.9 0.1 0.0022 18.2 0.1 1.3 1 0 0 1 1 1 1 Homeobox associated leucine zipper Ank_5 PF13857.6 KXS15402.1 - 0.0089 16.3 0.0 4.3 7.8 0.0 3.5 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Cnn_1N PF07989.11 KXS15402.1 - 0.012 15.8 0.1 0.035 14.3 0.0 1.7 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 HicA_toxin PF07927.12 KXS15402.1 - 0.13 12.3 0.1 2.2 8.4 0.1 3.0 3 0 0 3 3 3 0 HicA toxin of bacterial toxin-antitoxin, DivIC PF04977.15 KXS15402.1 - 0.17 11.6 0.1 0.31 10.8 0.1 1.3 1 0 0 1 1 1 0 Septum formation initiator ZapB PF06005.12 KXS15402.1 - 0.18 12.2 0.0 0.4 11.2 0.0 1.5 1 0 0 1 1 1 0 Cell division protein ZapB YvbH_ext PF11724.8 KXS15402.1 - 0.2 12.0 0.0 0.65 10.4 0.0 1.9 2 0 0 2 2 2 0 YvbH-like oligomerisation region bZIP_1 PF00170.21 KXS15402.1 - 6.9 6.9 5.7 0.36 10.9 0.2 1.6 2 0 0 2 2 1 0 bZIP transcription factor ubiquitin PF00240.23 KXS15403.1 - 2.2e-138 450.2 17.6 7e-34 115.4 0.4 4.0 4 0 0 4 4 4 4 Ubiquitin family Rad60-SLD PF11976.8 KXS15403.1 - 2.8e-66 219.3 19.3 6.2e-16 58.0 0.5 4.0 4 0 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KXS15403.1 - 8.1e-24 83.9 8.2 0.00037 20.9 0.1 5.8 4 4 0 4 4 4 4 Ubiquitin-like domain TBK1_ULD PF18396.1 KXS15403.1 - 1.2e-15 57.2 4.1 0.036 14.0 0.0 4.2 4 0 0 4 4 4 4 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 KXS15403.1 - 4.3e-14 52.6 3.0 0.14 12.3 0.0 5.0 4 4 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 KXS15403.1 - 6.3e-14 52.1 9.1 0.047 14.0 0.1 4.1 4 0 0 4 4 4 4 Ubiquitin-like domain DUF2407 PF10302.9 KXS15403.1 - 6.9e-14 52.3 0.9 0.23 12.0 0.0 4.2 1 1 2 4 4 4 4 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 KXS15403.1 - 6e-09 35.9 0.3 1.9 8.3 0.0 4.2 1 1 3 4 4 4 4 Silencing defective 2 N-terminal ubiquitin domain Methyltrans_RNA PF04452.14 KXS15403.1 - 3e-07 30.0 1.2 0.74 9.1 0.0 3.4 3 0 0 3 3 3 3 RNA methyltransferase Ubiquitin_4 PF18036.1 KXS15403.1 - 5.6e-07 29.5 24.5 11 6.1 0.2 7.9 8 0 0 8 8 8 0 Ubiquitin-like domain DUF3861 PF12977.7 KXS15403.1 - 8.6e-07 29.0 2.8 8.7 6.6 0.0 4.2 4 0 0 4 4 4 0 Domain of Unknown Function with PDB structure (DUF3861) Big_7 PF17957.1 KXS15403.1 - 2.4e-05 25.0 0.0 46 4.9 0.0 4.1 4 0 0 4 4 4 0 Bacterial Ig domain UDP-g_GGTase PF06427.11 KXS15403.1 - 3.7e-05 23.8 4.7 4.6 7.4 0.0 4.1 4 0 0 4 4 4 3 UDP-glucose:Glycoprotein Glucosyltransferase ACT_5 PF13710.6 KXS15403.1 - 3.7e-05 23.5 4.4 14 5.6 0.0 4.3 4 0 0 4 4 4 0 ACT domain DUF2870 PF11069.8 KXS15403.1 - 3.8e-05 24.0 0.0 49 4.4 0.0 4.8 4 0 0 4 4 4 0 Protein of unknown function (DUF2870) ACT_4 PF13291.6 KXS15403.1 - 0.00013 22.5 0.8 57 4.4 0.0 4.3 4 0 0 4 4 4 0 ACT domain DUF969 PF06149.12 KXS15403.1 - 0.00024 20.6 0.1 20 4.5 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF969) ProRS-C_2 PF09181.10 KXS15403.1 - 0.012 15.7 6.4 54 4.0 0.1 4.1 4 0 0 4 4 4 0 Prolyl-tRNA synthetase, C-terminal ORF11CD3 PF10549.9 KXS15403.1 - 0.026 14.7 0.0 1.5e+02 2.6 0.0 4.4 4 0 0 4 4 4 0 ORF11CD3 domain YukD PF08817.10 KXS15403.1 - 0.027 15.2 0.2 2.5e+02 2.5 0.0 4.1 4 0 0 4 4 4 0 WXG100 protein secretion system (Wss), protein YukD DUF493 PF04359.14 KXS15403.1 - 0.029 15.0 0.1 2.5e+02 2.3 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF493) Phage_sheath_1N PF17481.2 KXS15403.1 - 0.038 14.5 7.1 24 5.5 0.6 4.0 1 1 2 3 3 3 0 Phage tail sheath protein beta-sandwich domain YcgR_2 PF12945.7 KXS15403.1 - 0.13 12.4 4.9 1.3e+02 2.8 0.1 4.1 4 0 0 4 4 4 0 Flagellar protein YcgR Tash_PEST PF07708.11 KXS15403.1 - 0.14 12.3 27.2 6.2 7.1 1.4 4.3 4 0 0 4 4 4 0 Tash protein PEST motif Plexin_cytopl PF08337.12 KXS15403.1 - 0.59 8.7 14.5 19 3.8 0.3 5.2 2 1 0 4 4 4 0 Plexin cytoplasmic RasGAP domain FlgD_ig PF13860.6 KXS15403.1 - 0.7 9.8 8.7 97 2.9 0.1 4.3 4 0 0 4 4 4 0 FlgD Ig-like domain PI3K_p85B PF02192.16 KXS15403.1 - 1.5 8.6 9.6 83 3.0 0.1 4.2 4 0 0 4 4 4 0 PI3-kinase family, p85-binding domain Rootletin PF15035.6 KXS15404.1 - 0.0055 16.7 3.7 0.037 14.0 1.6 2.5 2 0 0 2 2 2 1 Ciliary rootlet component, centrosome cohesion Enkurin PF13864.6 KXS15404.1 - 0.054 13.9 2.2 0.11 13.0 0.0 2.5 3 0 0 3 3 3 0 Calmodulin-binding DUF1798 PF08807.10 KXS15404.1 - 0.24 11.6 0.6 0.88 9.7 0.1 2.2 2 0 0 2 2 2 0 Bacterial domain of unknown function (DUF1798) FUSC PF04632.12 KXS15404.1 - 0.32 9.5 6.1 0.64 8.5 6.1 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family zf-CCHC_3 PF13917.6 KXS15404.1 - 1.6 8.7 7.4 3.1 7.8 7.4 1.5 1 0 0 1 1 1 0 Zinc knuckle FAD_binding_2 PF00890.24 KXS15405.1 - 7.7e-20 71.3 0.0 8.8e-20 71.2 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain NAD_binding_6 PF08030.12 KXS15406.1 - 3.4e-09 37.0 0.0 4e-09 36.8 0.0 1.0 1 0 0 1 1 1 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 KXS15406.1 - 2.9e-05 24.7 0.0 0.0053 17.4 0.1 2.2 1 1 1 2 2 2 2 Oxidoreductase NAD-binding domain Ferric_reduct PF01794.19 KXS15407.1 - 9.3e-19 67.8 8.6 9.3e-19 67.8 8.6 1.9 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KXS15407.1 - 1.2e-07 31.9 0.0 1.7e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 KXS15407.1 - 3.6e-05 24.4 0.2 0.0023 18.5 0.2 2.4 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_8 PF08022.12 KXS15407.1 - 0.0078 16.3 0.0 0.017 15.2 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain FIN1 PF17300.2 KXS15407.1 - 0.29 10.6 0.1 0.44 10.0 0.1 1.1 1 0 0 1 1 1 0 Filaments in between nuclei protein-1 Pro_isomerase PF00160.21 KXS15408.1 - 1e-43 149.4 0.0 1.3e-43 149.0 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD GCD14 PF08704.10 KXS15409.1 - 2.7e-84 282.7 0.1 1.4e-83 280.3 0.1 1.8 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.6 KXS15409.1 - 1.4e-07 31.5 0.0 2.1e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain GCD14_N PF14801.6 KXS15409.1 - 4.6e-07 29.6 0.0 1.5e-06 27.9 0.0 1.9 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit N-term PCMT PF01135.19 KXS15409.1 - 1.1e-05 25.4 0.0 1.5e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Fibrillarin PF01269.17 KXS15409.1 - 0.002 17.3 0.0 0.0032 16.6 0.0 1.3 1 0 0 1 1 1 1 Fibrillarin Methyltransf_25 PF13649.6 KXS15409.1 - 0.0044 17.7 0.0 0.01 16.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain FtsJ PF01728.19 KXS15409.1 - 0.0071 16.5 0.0 0.011 15.9 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_24 PF13578.6 KXS15409.1 - 0.049 14.7 0.0 0.092 13.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltr_RsmB-F PF01189.17 KXS15409.1 - 0.14 11.8 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F LRR_4 PF12799.7 KXS15410.1 - 3.5e-07 30.4 11.6 0.0032 17.8 0.3 2.4 1 1 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXS15410.1 - 0.0068 16.1 7.7 0.023 14.4 1.8 2.4 1 1 2 3 3 3 2 Leucine rich repeat LRR_6 PF13516.6 KXS15410.1 - 0.055 13.5 1.5 15 6.0 0.1 2.8 2 0 0 2 2 2 0 Leucine Rich repeat Protocadherin PF08374.11 KXS15410.1 - 0.064 13.2 0.0 0.089 12.8 0.0 1.2 1 0 0 1 1 1 0 Protocadherin LRR_1 PF00560.33 KXS15410.1 - 0.067 13.8 14.1 1.9 9.3 0.8 3.7 3 0 0 3 3 3 0 Leucine Rich Repeat Syndecan PF01034.20 KXS15410.1 - 0.12 12.4 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 Syndecan domain Beta-APP PF03494.13 KXS15410.1 - 0.32 10.9 2.8 0.17 11.7 0.6 1.7 1 1 1 2 2 2 0 Beta-amyloid peptide (beta-APP) LRR_4 PF12799.7 KXS15411.1 - 4e-13 49.3 11.4 0.0017 18.7 3.0 3.9 2 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXS15411.1 - 5e-09 35.8 8.6 5.3e-07 29.3 0.6 3.4 1 1 1 3 3 3 3 Leucine rich repeat LRR_1 PF00560.33 KXS15411.1 - 0.86 10.4 16.7 2.5 9.0 0.3 5.9 5 2 0 5 5 5 0 Leucine Rich Repeat Glyco_transf_25 PF01755.17 KXS15414.1 - 5.3e-11 42.8 0.0 1e-10 41.8 0.0 1.5 1 1 1 2 2 2 1 Glycosyltransferase family 25 (LPS biosynthesis protein) DnaJ PF00226.31 KXS15415.1 - 1.7e-24 85.7 0.1 2.7e-24 85.1 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain NBP1 PF08537.10 KXS15416.1 - 0.0094 15.4 4.3 0.018 14.4 4.3 1.4 1 0 0 1 1 1 1 Fungal Nap binding protein NBP1 DUF1644 PF07800.12 KXS15416.1 - 0.051 13.6 0.9 0.051 13.6 0.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1644) TPR_MLP1_2 PF07926.12 KXS15416.1 - 0.15 12.1 6.5 0.24 11.4 6.5 1.2 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein CCDC-167 PF15188.6 KXS15416.1 - 0.26 11.6 8.7 0.5 10.7 8.7 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 Lar_restr_allev PF14354.6 KXS15416.1 - 0.31 11.5 2.7 0.63 10.5 2.7 1.4 1 0 0 1 1 1 0 Restriction alleviation protein Lar zf-H2C2_2 PF13465.6 KXS15416.1 - 1.4 9.5 4.1 20 5.8 0.0 3.0 3 0 0 3 3 3 0 Zinc-finger double domain DUF4140 PF13600.6 KXS15416.1 - 4.8 7.7 6.0 69 4.0 6.0 2.3 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Pro_isomerase PF00160.21 KXS15417.1 - 2.7e-49 167.5 0.4 3.4e-49 167.1 0.4 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Glyco_transf_25 PF01755.17 KXS15418.1 - 1.6e-08 34.7 0.0 2.2e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) GvpL_GvpF PF06386.11 KXS15422.1 - 0.045 13.7 0.7 0.07 13.1 0.7 1.2 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Epiglycanin_TR PF05647.11 KXS15422.1 - 0.13 12.2 17.4 0.031 14.2 13.8 1.9 2 0 0 2 2 2 0 Tandem-repeating region of mucin, epiglycanin-like Thioredoxin_12 PF18400.1 KXS15425.1 - 0.1 12.4 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like domain ESR1_C PF12743.7 KXS15427.1 - 1.7 8.5 6.2 0.95 9.3 4.2 1.6 2 0 0 2 2 2 0 Oestrogen-type nuclear receptor final C-terminal CBM53 PF16760.5 KXS15428.1 - 0.0001 22.8 0.0 0.03 14.9 0.0 2.2 2 0 0 2 2 2 2 Starch/carbohydrate-binding module (family 53) CBM_21 PF03370.13 KXS15428.1 - 0.064 13.4 0.0 0.11 12.7 0.0 1.4 1 1 0 1 1 1 0 Carbohydrate/starch-binding module (family 21) Fe_hyd_lg_C PF02906.14 KXS15429.1 - 5.1e-80 268.6 0.0 6.7e-80 268.2 0.0 1.1 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Fe_hyd_SSU PF02256.17 KXS15429.1 - 2.5e-25 88.3 4.1 4.2e-25 87.6 4.1 1.4 1 0 0 1 1 1 1 Iron hydrogenase small subunit Fer4 PF00037.27 KXS15429.1 - 5.6e-10 38.6 18.5 6.5e-07 28.9 2.3 3.4 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_7 PF12838.7 KXS15429.1 - 3.6e-09 37.1 17.3 2.9e-07 31.0 8.0 2.6 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 KXS15429.1 - 1.1e-08 35.0 6.0 0.0014 18.7 0.6 2.7 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 KXS15429.1 - 4.1e-08 33.0 12.5 0.00035 20.5 2.0 2.7 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_21 PF14697.6 KXS15429.1 - 1.5e-07 31.5 6.6 5.2e-07 29.7 6.6 2.0 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 KXS15429.1 - 4e-07 30.4 17.2 7.6e-06 26.3 8.8 2.6 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 KXS15429.1 - 5.4e-06 26.5 9.4 6.2e-06 26.3 6.8 2.5 2 1 1 3 3 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 KXS15429.1 - 9.2e-06 26.5 12.1 0.001 19.9 0.8 3.6 3 0 0 3 3 3 2 4Fe-4S double cluster binding domain Fer4_2 PF12797.7 KXS15429.1 - 1.6e-05 24.7 12.8 0.025 14.7 4.1 3.0 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 KXS15429.1 - 0.00039 20.9 11.6 0.027 15.0 12.5 2.7 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_4 PF12800.7 KXS15429.1 - 0.00075 19.8 14.9 0.047 14.2 1.4 3.1 3 0 0 3 3 2 2 4Fe-4S binding domain Fer4_22 PF17179.4 KXS15429.1 - 0.016 16.0 11.3 0.66 10.9 0.7 3.1 3 0 0 3 3 2 0 4Fe-4S dicluster domain Fer4_15 PF13459.6 KXS15429.1 - 0.062 14.0 7.5 2 9.2 0.3 3.5 3 0 0 3 3 3 0 4Fe-4S single cluster domain Fer4_3 PF12798.7 KXS15429.1 - 0.067 14.1 4.8 0.067 14.1 4.8 3.3 3 0 0 3 3 2 0 4Fe-4S binding domain Fer4_18 PF13746.6 KXS15429.1 - 0.094 12.9 5.9 2.3 8.4 0.8 2.6 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_13 PF13370.6 KXS15429.1 - 0.35 11.4 13.9 3.6 8.2 0.7 3.9 4 0 0 4 4 3 0 4Fe-4S single cluster domain of Ferredoxin I Hemerythrin PF01814.23 KXS15430.1 - 5.6e-10 40.0 0.7 9.3e-10 39.2 0.4 1.6 2 0 0 2 2 2 1 Hemerythrin HHE cation binding domain MauJ PF17419.2 KXS15430.1 - 0.0015 18.0 0.1 0.0025 17.4 0.0 1.4 1 1 0 1 1 1 1 Methylamine utilization protein MauJ DUF935 PF06074.12 KXS15430.1 - 0.0058 15.4 0.1 0.0073 15.1 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF935) DUF202 PF02656.15 KXS15433.1 - 0.0063 16.9 1.6 6 7.4 0.1 3.1 2 0 0 2 2 2 2 Domain of unknown function (DUF202) ATP-synt_I PF03899.15 KXS15433.1 - 0.095 13.1 4.9 3.1 8.2 0.1 3.5 3 0 0 3 3 3 0 ATP synthase I chain DUF5111 PF17138.4 KXS15433.1 - 0.097 12.5 0.3 6.6 6.6 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF5111) DUF3185 PF11381.8 KXS15433.1 - 0.36 10.9 9.9 2.3 8.3 0.8 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3185) UMPH-1 PF05822.12 KXS15434.1 - 8.5e-66 222.0 0.0 1.3e-65 221.4 0.0 1.2 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) HAD PF12710.7 KXS15434.1 - 3.8e-05 24.2 0.3 0.00035 21.0 0.0 2.3 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cellulase-like PF12876.7 KXS15434.1 - 0.13 11.6 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Sugar-binding cellulase-like MFS_1 PF07690.16 KXS15435.1 - 6.9e-07 28.5 7.8 7.1e-07 28.5 7.8 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily DLH PF01738.18 KXS15437.1 - 3.1e-07 30.2 0.1 5.2e-07 29.4 0.1 1.3 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 KXS15437.1 - 7.7e-05 22.5 0.0 0.00011 22.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXS15437.1 - 0.019 14.3 0.0 0.026 13.8 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 KXS15437.1 - 0.087 12.4 0.1 0.14 11.7 0.1 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) BAAT_C PF08840.11 KXS15437.1 - 0.17 11.8 0.1 0.25 11.2 0.1 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Transp_cyt_pur PF02133.15 KXS15440.1 - 4.4e-25 88.4 32.5 7e-25 87.7 32.5 1.3 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF4131 PF13567.6 KXS15440.1 - 0.045 13.4 0.3 0.045 13.4 0.3 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF4131) DUF3754 PF12576.8 KXS15440.1 - 0.064 13.2 0.9 0.89 9.5 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3754) DUF5336 PF17270.2 KXS15440.1 - 1.9 8.1 15.7 0.82 9.3 2.1 2.9 3 0 0 3 3 3 0 Family of unknown function (DUF5336) Aminotran_3 PF00202.21 KXS15441.1 - 1.4e-26 93.1 0.0 7.2e-18 64.4 0.0 2.1 1 1 1 2 2 2 2 Aminotransferase class-III DnaJ-X PF14308.6 KXS15443.1 - 3e-38 131.4 0.3 2.4e-36 125.2 0.1 2.3 2 0 0 2 2 2 2 X-domain of DnaJ-containing DnaJ PF00226.31 KXS15443.1 - 3.8e-23 81.4 0.2 1e-22 80.0 0.2 1.8 1 0 0 1 1 1 1 DnaJ domain zinc_ribbon_4 PF13717.6 KXS15443.1 - 0.0066 16.4 1.0 0.015 15.2 1.0 1.5 1 0 0 1 1 1 1 zinc-ribbon domain Peptidase_M48 PF01435.18 KXS15446.1 - 1.2e-10 41.5 1.4 5.9e-10 39.2 0.2 2.4 2 1 0 2 2 2 1 Peptidase family M48 DUF2268 PF10026.9 KXS15446.1 - 0.0051 16.4 0.0 0.0098 15.5 0.0 1.5 1 1 0 1 1 1 1 Predicted Zn-dependent protease (DUF2268) SprT-like PF10263.9 KXS15446.1 - 0.12 12.3 0.2 0.22 11.4 0.2 1.4 1 0 0 1 1 1 0 SprT-like family Mannosyl_trans3 PF11051.8 KXS15448.1 - 1.2e-44 152.7 0.0 2e-44 152.0 0.0 1.3 1 1 0 1 1 1 1 Mannosyltransferase putative p450 PF00067.22 KXS15449.1 - 0.024 13.4 0.0 0.029 13.1 0.0 1.0 1 0 0 1 1 1 0 Cytochrome P450 p450 PF00067.22 KXS15450.1 - 4.4e-45 154.3 0.1 9.5e-45 153.2 0.1 1.5 1 1 0 1 1 1 1 Cytochrome P450 VOMI PF03762.17 KXS15450.1 - 0.15 12.2 0.0 0.23 11.6 0.0 1.2 1 0 0 1 1 1 0 Vitelline membrane outer layer protein I (VOMI) ADH_zinc_N_2 PF13602.6 KXS15451.1 - 1.4e-16 61.7 0.0 2.3e-16 61.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glutaredoxin PF00462.24 KXS15452.1 - 1e-15 57.7 0.0 2e-15 56.7 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin HrpB7 PF09486.10 KXS15453.1 - 1.7 9.0 6.6 0.068 13.5 0.5 1.7 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) F-box PF00646.33 KXS15456.1 - 0.0072 16.2 0.1 0.02 14.7 0.1 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KXS15456.1 - 0.01 15.7 0.4 0.023 14.6 0.4 1.6 1 0 0 1 1 1 0 F-box-like PRIMA1 PF16101.5 KXS15456.1 - 1.1 9.3 3.3 2.4 8.2 3.3 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Tim44 PF04280.15 KXS15457.1 - 7.2e-29 100.8 0.3 1.9e-28 99.4 0.0 1.9 2 0 0 2 2 2 1 Tim44-like domain LUC7 PF03194.15 KXS15457.1 - 1.4 8.6 5.0 2 8.0 5.0 1.2 1 0 0 1 1 1 0 LUC7 N_terminus PQQ_2 PF13360.6 KXS15458.1 - 1.9e-20 73.5 0.4 2.2e-09 37.3 0.1 2.3 2 0 0 2 2 2 2 PQQ-like domain PQQ PF01011.21 KXS15458.1 - 1.3e-17 62.8 2.0 0.00043 20.1 0.0 4.4 4 0 0 4 4 4 4 PQQ enzyme repeat PQQ_3 PF13570.6 KXS15458.1 - 5e-14 52.3 9.3 0.00016 22.0 2.8 5.2 5 0 0 5 5 5 4 PQQ-like domain PQQ_2 PF13360.6 KXS15459.1 - 4.8e-19 68.9 0.4 7.3e-18 65.0 0.4 2.2 1 1 0 1 1 1 1 PQQ-like domain PQQ PF01011.21 KXS15459.1 - 1.1e-14 53.5 1.2 0.016 15.1 0.0 4.3 4 0 0 4 4 4 4 PQQ enzyme repeat PQQ_3 PF13570.6 KXS15459.1 - 4.9e-09 36.4 0.2 0.015 15.8 0.2 4.8 4 1 0 4 4 4 3 PQQ-like domain adh_short PF00106.25 KXS15460.1 - 7.9e-43 146.2 2.1 5.7e-39 133.6 0.1 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXS15460.1 - 7.5e-36 123.8 0.0 7.5e-36 123.8 0.0 1.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXS15460.1 - 2.1e-05 24.5 1.0 5e-05 23.3 1.0 1.6 1 1 0 1 1 1 1 KR domain Peptidase_C11 PF03415.14 KXS15460.1 - 0.027 13.9 0.0 0.03 13.7 0.0 1.1 1 0 0 1 1 1 0 Clostripain family His_Phos_1 PF00300.22 KXS15461.1 - 3e-32 111.9 0.1 5.7e-32 111.0 0.1 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) F-box-like PF12937.7 KXS15463.1 - 3.2e-10 39.7 1.0 3.2e-10 39.7 1.0 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KXS15463.1 - 3.9e-06 26.6 1.4 2.9e-05 23.8 0.2 2.6 2 0 0 2 2 2 1 F-box domain CbiA PF01656.23 KXS15463.1 - 0.14 12.2 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Peptidase_M55 PF04951.13 KXS15464.1 - 1.5 8.2 3.9 1.9 7.8 3.9 1.2 1 0 0 1 1 1 0 D-aminopeptidase FAD_binding_3 PF01494.19 KXS15467.1 - 6.4e-13 48.7 0.0 2.1e-06 27.2 0.0 2.5 2 1 0 2 2 2 2 FAD binding domain SE PF08491.10 KXS15467.1 - 0.00082 18.5 0.0 0.045 12.8 0.0 2.1 2 0 0 2 2 2 2 Squalene epoxidase DAO PF01266.24 KXS15467.1 - 0.061 12.9 0.0 2.4 7.6 0.0 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KXS15467.1 - 0.13 12.2 0.1 0.82 9.6 0.1 2.3 1 1 0 1 1 1 0 FAD-NAD(P)-binding Zn_clus PF00172.18 KXS15468.1 - 1.2e-06 28.6 9.1 1.2e-06 28.6 9.1 1.5 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 KXS15470.1 - 1.1e-07 31.8 15.3 2.1e-07 31.0 15.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-RING_11 PF17123.5 KXS15471.1 - 0.0017 18.1 0.0 0.0031 17.2 0.0 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 KXS15471.1 - 0.15 12.4 0.0 0.33 11.3 0.0 1.6 1 0 0 1 1 1 0 Ring finger domain DUF1254 PF06863.12 KXS15473.1 - 1e-15 58.0 0.0 1.5e-15 57.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1254) EF-hand_7 PF13499.6 KXS15474.1 - 3.8e-20 72.1 3.0 3.3e-11 43.5 0.5 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KXS15474.1 - 1.1e-16 59.0 8.2 2.2e-06 26.8 0.7 4.0 4 0 0 4 4 4 3 EF hand EF-hand_5 PF13202.6 KXS15474.1 - 7.7e-14 50.5 3.9 2.4e-05 23.6 0.1 4.1 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 KXS15474.1 - 7.5e-13 47.3 4.5 0.00027 20.6 0.3 4.1 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 KXS15474.1 - 1.9e-06 27.6 9.3 0.00046 20.0 0.5 3.6 2 2 2 4 4 4 3 EF-hand domain pair Dockerin_1 PF00404.18 KXS15474.1 - 0.0015 18.6 0.0 7.4 6.9 0.0 3.2 3 0 0 3 3 3 1 Dockerin type I domain EF-hand_4 PF12763.7 KXS15474.1 - 0.012 15.5 0.9 22 5.1 0.1 3.2 2 2 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand EF-hand_11 PF08976.11 KXS15474.1 - 0.021 15.7 0.2 0.75 10.7 0.0 2.1 1 1 1 2 2 2 0 EF-hand domain DHC_N2 PF08393.13 KXS15474.1 - 0.035 13.2 0.5 0.044 12.9 0.5 1.1 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 2 YcxB PF14317.6 KXS15474.1 - 0.064 13.0 0.2 0.23 11.2 0.1 1.9 2 0 0 2 2 2 0 YcxB-like protein EF-hand_10 PF14788.6 KXS15474.1 - 0.15 11.9 1.0 30 4.6 0.1 3.1 3 1 0 3 3 3 0 EF hand DUF4209 PF13910.6 KXS15476.1 - 3e-15 56.2 0.0 7.6e-15 54.9 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4209) DUF3752 PF12572.8 KXS15479.1 - 1.9e-23 83.7 1.5 1.9e-23 83.7 1.5 3.2 3 0 0 3 3 3 1 Protein of unknown function (DUF3752) Transp_cyt_pur PF02133.15 KXS15480.1 - 3.6e-31 108.4 39.0 5.2e-31 107.9 39.0 1.2 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin tRNA-synt_2 PF00152.20 KXS15481.1 - 7.6e-71 238.8 0.0 5.5e-58 196.5 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KXS15481.1 - 2.9e-09 36.8 0.0 7e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA_anti_2 PF13742.6 KXS15481.1 - 0.18 12.1 0.0 0.35 11.1 0.0 1.4 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain Pkinase PF00069.25 KXS15482.1 - 3.8e-62 210.1 0.0 4.9e-62 209.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS15482.1 - 9.7e-40 136.5 0.0 6.7e-39 133.7 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXS15482.1 - 1.2e-06 28.0 0.0 1.9e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KXS15482.1 - 0.0003 20.8 0.2 0.014 15.4 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXS15482.1 - 0.015 14.1 0.0 0.027 13.3 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 KXS15482.1 - 0.068 12.1 0.0 0.13 11.1 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain TPR_14 PF13428.6 KXS15484.1 - 9.7e-14 50.9 26.3 0.0048 17.6 2.3 7.5 7 2 2 9 9 7 4 Tetratricopeptide repeat TPR_19 PF14559.6 KXS15484.1 - 1.9e-10 41.1 1.5 0.0055 17.2 0.1 5.1 4 1 2 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 KXS15484.1 - 4e-10 39.0 10.5 0.1 12.8 0.0 6.8 6 0 0 6 6 6 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KXS15484.1 - 2.1e-08 34.3 0.2 0.036 14.3 0.1 4.0 4 0 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 KXS15484.1 - 4.6e-08 33.2 12.8 0.032 14.5 0.0 5.5 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 KXS15484.1 - 3.8e-07 29.6 1.3 0.31 10.9 0.2 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 KXS15484.1 - 1.3e-06 28.0 0.0 0.053 13.2 0.0 3.9 3 1 1 4 4 4 2 TPR repeat TPR_16 PF13432.6 KXS15484.1 - 3.9e-06 27.4 18.0 0.11 13.2 3.2 5.4 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 KXS15484.1 - 0.00032 20.5 5.6 1.1 9.4 0.1 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 KXS15484.1 - 0.0047 17.0 0.2 1.5 9.2 0.1 4.2 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 KXS15484.1 - 0.0063 16.8 0.3 4.2 8.0 0.0 4.5 4 1 1 5 5 4 1 Tetratricopeptide repeat DHC_N1 PF08385.12 KXS15484.1 - 0.027 13.1 0.2 0.041 12.5 0.2 1.2 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 1 Coatomer_E PF04733.14 KXS15484.1 - 0.059 12.8 0.0 13 5.0 0.0 2.7 3 0 0 3 3 3 0 Coatomer epsilon subunit C2 PF00168.30 KXS15484.1 - 0.1 12.9 0.0 0.26 11.6 0.0 1.7 1 0 0 1 1 1 0 C2 domain TPR_15 PF13429.6 KXS15484.1 - 0.26 10.5 6.1 7.9 5.6 0.1 3.9 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 KXS15484.1 - 2.6 8.9 4.4 59 4.6 0.2 4.2 4 0 0 4 4 3 0 Tetratricopeptide repeat Metallophos PF00149.28 KXS15485.1 - 4.2e-38 131.9 0.1 6.1e-38 131.4 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KXS15485.1 - 0.001 19.5 1.3 0.0025 18.2 1.3 1.7 1 1 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain TAD2 PF18521.1 KXS15485.1 - 0.019 14.9 1.2 0.043 13.8 1.2 1.6 1 0 0 1 1 1 0 Transactivation domain 2 Metallophos_2 PF12850.7 KXS15485.1 - 0.02 15.1 0.0 0.03 14.5 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain CPBP PF02517.16 KXS15486.1 - 4.7e-16 58.9 2.4 4.7e-16 58.9 2.4 2.0 2 1 0 2 2 2 1 CPBP intramembrane metalloprotease CENP-T_C PF15511.6 KXS15487.1 - 3.9e-08 33.4 0.1 4.8e-08 33.1 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 KXS15487.1 - 7.2e-05 22.9 0.1 0.0001 22.4 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 KXS15487.1 - 0.00013 22.2 0.1 0.00017 21.9 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 KXS15487.1 - 0.0011 19.2 0.1 0.0022 18.2 0.0 1.7 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KXS15487.1 - 0.0018 18.7 0.2 0.0022 18.3 0.1 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KXS15487.1 - 0.031 14.4 0.0 0.035 14.2 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Histone PF00125.24 KXS15488.1 - 3.2e-52 176.4 2.7 3.5e-52 176.2 2.7 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 KXS15488.1 - 2.3e-05 24.7 0.0 3.5e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 KXS15488.1 - 3e-05 24.1 0.4 4.8e-05 23.4 0.1 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 KXS15488.1 - 0.00018 22.1 1.1 0.00021 21.9 1.1 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 KXS15488.1 - 0.0057 16.9 0.0 0.011 16.0 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KXS15488.1 - 0.057 13.5 0.1 0.11 12.6 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KXS15488.1 - 0.1 12.6 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated ubiquitin PF00240.23 KXS15491.1 - 1.8e-104 341.6 11.2 4.1e-34 116.2 0.4 3.0 3 0 0 3 3 3 3 Ubiquitin family Rad60-SLD PF11976.8 KXS15491.1 - 2.2e-50 168.4 12.5 3.6e-16 58.7 0.5 3.0 3 0 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KXS15491.1 - 1.4e-18 67.1 4.3 0.00022 21.6 0.1 4.5 3 3 0 3 3 3 3 Ubiquitin-like domain TBK1_ULD PF18396.1 KXS15491.1 - 6.5e-12 45.2 2.3 0.022 14.7 0.1 3.2 3 0 0 3 3 3 3 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 KXS15491.1 - 1.2e-11 44.8 2.9 0.021 15.2 0.1 3.1 1 1 1 3 3 3 3 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 KXS15491.1 - 5.9e-11 42.4 1.3 0.081 13.0 0.0 3.9 3 3 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 KXS15491.1 - 1.9e-10 41.2 0.2 0.13 12.9 0.0 3.2 1 1 1 3 3 3 3 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 KXS15491.1 - 7.1e-07 29.2 0.1 1.1 9.1 0.0 3.2 1 1 2 3 3 3 3 Silencing defective 2 N-terminal ubiquitin domain Ubiquitin_4 PF18036.1 KXS15491.1 - 3.2e-06 27.1 16.4 7.4 6.7 0.2 6.0 6 0 0 6 6 6 0 Ubiquitin-like domain DUF3861 PF12977.7 KXS15491.1 - 2.2e-05 24.5 0.9 5.3 7.3 0.0 3.2 3 0 0 3 3 3 3 Domain of Unknown Function with PDB structure (DUF3861) Methyltrans_RNA PF04452.14 KXS15491.1 - 9e-05 21.9 0.3 0.45 9.8 0.0 2.5 2 0 0 2 2 2 2 RNA methyltransferase ACT_5 PF13710.6 KXS15491.1 - 0.00036 20.3 1.9 9.6 6.1 0.0 3.3 3 0 0 3 3 3 0 ACT domain Big_7 PF17957.1 KXS15491.1 - 0.0008 20.1 0.1 30 5.5 0.0 3.2 3 0 0 3 3 3 0 Bacterial Ig domain UDP-g_GGTase PF06427.11 KXS15491.1 - 0.00094 19.3 1.9 2.9 8.1 0.0 3.2 3 0 0 3 3 3 2 UDP-glucose:Glycoprotein Glucosyltransferase DUF2870 PF11069.8 KXS15491.1 - 0.00096 19.5 0.1 33 4.9 0.0 3.8 3 3 0 3 3 3 0 Protein of unknown function (DUF2870) ACT_4 PF13291.6 KXS15491.1 - 0.0022 18.6 0.2 39 4.9 0.0 3.3 3 0 0 3 3 3 0 ACT domain DUF969 PF06149.12 KXS15491.1 - 0.0047 16.4 0.0 12 5.2 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF969) RBD PF02196.15 KXS15491.1 - 0.021 14.9 0.0 68 3.7 0.0 3.3 3 0 0 3 3 3 0 Raf-like Ras-binding domain ProRS-C_2 PF09181.10 KXS15491.1 - 0.023 14.8 3.0 37 4.5 0.1 3.2 3 0 0 3 3 3 0 Prolyl-tRNA synthetase, C-terminal Phage_sheath_1N PF17481.2 KXS15491.1 - 0.066 13.7 4.0 38 4.8 0.1 3.1 1 1 2 3 3 3 0 Phage tail sheath protein beta-sandwich domain Tash_PEST PF07708.11 KXS15491.1 - 0.13 12.4 18.4 4.5 7.6 1.4 3.3 3 0 0 3 3 3 0 Tash protein PEST motif YcgR_2 PF12945.7 KXS15491.1 - 0.14 12.3 2.1 86 3.4 0.1 3.2 3 0 0 3 3 3 0 Flagellar protein YcgR Plexin_cytopl PF08337.12 KXS15491.1 - 0.34 9.5 9.6 13 4.3 0.7 4.2 2 1 0 3 3 3 0 Plexin cytoplasmic RasGAP domain FlgD_ig PF13860.6 KXS15491.1 - 0.37 10.7 4.6 65 3.5 0.1 3.4 3 0 0 3 3 3 0 FlgD Ig-like domain DMA PF03474.14 KXS15491.1 - 0.4 10.3 1.7 1.1e+02 2.5 0.0 3.3 3 0 0 3 3 3 0 DMRTA motif PI3K_p85B PF02192.16 KXS15491.1 - 0.7 9.7 5.3 58 3.5 0.1 3.2 3 0 0 3 3 3 0 PI3-kinase family, p85-binding domain Zn_clus PF00172.18 KXS15492.1 - 1.3e-05 25.2 2.6 2.2e-05 24.4 2.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pro-MCH PF05824.12 KXS15493.1 - 0.038 13.9 0.0 0.082 12.8 0.0 1.5 1 0 0 1 1 1 0 Pro-melanin-concentrating hormone (Pro-MCH) DUF1320 PF07030.12 KXS15493.1 - 0.05 13.7 0.1 0.68 10.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1320) RRM_1 PF00076.22 KXS15494.1 - 5.4e-10 39.0 0.0 9.3e-10 38.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Retrotran_gag_2 PF14223.6 KXS15495.1 - 1.8e-10 40.6 0.1 2.8e-10 40.0 0.1 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type FCD PF07729.12 KXS15496.1 - 0.004 17.6 0.5 0.0096 16.3 0.5 1.6 1 1 1 2 2 2 1 FCD domain Baculo_p74 PF04583.12 KXS15496.1 - 0.14 11.6 0.0 0.18 11.2 0.0 1.1 1 0 0 1 1 1 0 Baculoviridae p74 conserved region Glyco_hydro_36 PF17167.4 KXS15496.1 - 0.17 10.5 0.0 0.19 10.4 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase 36 superfamily, catalytic domain WBP-1 PF11669.8 KXS15497.1 - 0.062 13.9 6.0 0.72 10.5 2.2 2.9 2 1 0 2 2 2 0 WW domain-binding protein 1 SOG2 PF10428.9 KXS15497.1 - 0.1 11.8 1.1 0.11 11.6 1.1 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein ANTH PF07651.16 KXS15498.1 - 4.5e-58 196.4 0.0 4.5e-58 196.4 0.0 2.9 3 0 0 3 3 3 1 ANTH domain I_LWEQ PF01608.17 KXS15498.1 - 6e-48 163.0 17.8 6e-48 163.0 17.8 7.3 4 3 3 7 7 7 2 I/LWEQ domain Thiolase_N PF00108.23 KXS15499.1 - 4e-17 62.4 0.0 1.6e-13 50.7 0.0 2.2 1 1 1 2 2 2 2 Thiolase, N-terminal domain Thiolase_C PF02803.18 KXS15499.1 - 4.2e-10 39.3 0.2 1.6e-09 37.5 0.1 2.1 2 0 0 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III PF08545.10 KXS15499.1 - 0.0039 17.0 0.0 0.11 12.4 0.0 2.8 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.26 KXS15499.1 - 0.0075 15.9 0.5 0.031 13.9 0.2 2.2 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain NAD_binding_8 PF13450.6 KXS15500.1 - 6.9e-08 32.6 0.6 2.4e-07 30.9 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.19 KXS15500.1 - 1.4e-05 23.7 0.0 0.00016 20.3 0.0 2.2 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like DAO PF01266.24 KXS15500.1 - 0.014 15.0 0.0 0.13 11.8 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXS15500.1 - 0.02 14.2 0.0 0.065 12.5 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KXS15500.1 - 0.33 10.2 2.2 0.16 11.2 0.2 1.5 2 0 0 2 2 2 0 FAD binding domain adh_short PF00106.25 KXS15501.1 - 1.7e-10 40.7 0.2 6e-07 29.1 0.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXS15501.1 - 1.8e-06 27.7 0.3 0.0079 15.8 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.8 KXS15501.1 - 0.0079 15.9 0.7 0.014 15.2 0.7 1.4 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 2-Hacid_dh_C PF02826.19 KXS15501.1 - 0.038 13.3 0.3 0.098 12.0 0.0 1.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ACT_6 PF13740.6 KXS15501.1 - 0.052 13.5 0.1 5.8 7.0 0.1 2.2 2 0 0 2 2 2 0 ACT domain NAD_binding_7 PF13241.6 KXS15501.1 - 0.13 12.7 0.0 0.15 12.5 0.0 1.3 1 1 0 1 1 1 0 Putative NAD(P)-binding Aldo_ket_red PF00248.21 KXS15503.1 - 3.3e-47 161.1 0.0 4.1e-47 160.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Pmp3 PF01679.17 KXS15504.1 - 5e-20 71.4 9.7 7e-20 71.0 9.7 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Lipase_3 PF01764.25 KXS15505.1 - 1.1e-13 51.3 0.0 1.9e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KXS15505.1 - 0.01 16.4 1.9 0.068 13.8 0.1 3.0 1 1 1 2 2 2 0 Alpha/beta hydrolase family Mito_fiss_reg PF05308.11 KXS15506.1 - 0.66 10.0 2.4 0.56 10.3 1.2 1.4 2 0 0 2 2 2 0 Mitochondrial fission regulator CAP_N PF01213.19 KXS15506.1 - 4.2 6.8 4.6 5.5 6.4 4.6 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal CH PF00307.31 KXS15507.1 - 4.2e-20 72.0 0.0 5.4e-20 71.6 0.0 1.2 1 0 0 1 1 1 1 Calponin homology (CH) domain Calponin PF00402.18 KXS15507.1 - 2.5e-07 30.2 11.8 0.0007 19.2 2.2 2.4 2 0 0 2 2 2 2 Calponin family repeat CDC24 PF06395.11 KXS15507.1 - 0.0081 16.4 0.1 0.012 15.9 0.1 1.3 1 0 0 1 1 1 1 CDC24 Calponin Glyco_transf_8 PF01501.20 KXS15508.1 - 6.3e-08 32.5 0.0 2.5e-07 30.5 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 8 zf-C3HC4_3 PF13920.6 KXS15509.1 - 3.7e-06 26.7 1.1 6.2e-06 26.0 1.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Ank_2 PF12796.7 KXS15510.1 - 8.9e-13 48.7 0.3 5.5e-08 33.3 0.1 3.2 2 2 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXS15510.1 - 2e-11 43.0 0.4 0.086 13.4 0.0 5.1 6 0 0 6 6 6 3 Ankyrin repeat Ank_4 PF13637.6 KXS15510.1 - 8.6e-09 35.8 0.1 0.0083 16.7 0.0 3.8 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXS15510.1 - 2e-08 34.3 2.9 0.01 16.1 0.0 4.5 1 1 4 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 KXS15510.1 - 8.3e-07 29.2 0.3 0.78 10.3 0.0 4.3 5 1 0 5 5 5 3 Ankyrin repeat DNA_pol_B_palm PF14792.6 KXS15510.1 - 0.12 12.6 0.0 0.44 10.8 0.0 1.8 2 0 0 2 2 2 0 DNA polymerase beta palm zf-PARP PF00645.18 KXS15511.1 - 0.0046 17.8 0.4 0.0081 17.0 0.4 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Noggin PF05806.12 KXS15511.1 - 0.035 14.0 0.3 0.052 13.5 0.3 1.2 1 0 0 1 1 1 0 Noggin ECH_1 PF00378.20 KXS15512.1 - 2e-42 145.2 0.0 2.5e-42 144.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXS15512.1 - 1.8e-34 119.7 0.0 2.2e-34 119.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Porphobil_deamC PF03900.15 KXS15512.1 - 0.15 12.4 0.6 4.1 7.9 0.0 2.4 1 1 1 2 2 2 0 Porphobilinogen deaminase, C-terminal domain RNA_Me_trans PF04252.13 KXS15513.1 - 2.7e-34 118.5 0.0 1.2e-33 116.4 0.0 1.8 1 1 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase DUF599 PF04654.12 KXS15515.1 - 8.9e-45 152.7 9.7 1.1e-44 152.3 9.7 1.1 1 0 0 1 1 1 1 Protein of unknown function, DUF599 TRIQK PF15168.6 KXS15515.1 - 1.5 8.8 4.9 0.74 9.7 0.4 2.5 3 0 0 3 3 3 0 Triple QxxK/R motif-containing protein family Rieske PF00355.26 KXS15516.1 - 3.7e-12 46.0 0.0 2e-05 24.5 0.0 2.3 2 0 0 2 2 2 2 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 KXS15516.1 - 4.1e-07 29.9 0.0 0.012 15.5 0.0 2.3 2 0 0 2 2 2 2 Rieske-like [2Fe-2S] domain Bd3614-deam PF14439.6 KXS15517.1 - 0.2 11.7 0.1 0.35 10.9 0.1 1.3 1 0 0 1 1 1 0 Bd3614-like deaminase E1-E2_ATPase PF00122.20 KXS15518.1 - 2.1e-22 79.5 6.2 1.2e-19 70.5 1.0 3.0 3 0 0 3 3 3 2 E1-E2 ATPase Hydrolase PF00702.26 KXS15518.1 - 2.9e-14 53.9 4.6 2.4e-06 28.0 1.0 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase P5-ATPase PF12409.8 KXS15518.1 - 3.4e-08 33.6 0.1 6.1e-05 23.1 0.0 2.5 2 0 0 2 2 2 2 P5-type ATPase cation transporter Cation_ATPase_N PF00690.26 KXS15518.1 - 0.0054 16.4 0.0 0.012 15.2 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus GST_N_2 PF13409.6 KXS15521.1 - 3.1e-11 43.4 0.0 5.2e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KXS15521.1 - 3.7e-11 43.2 0.0 7.5e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KXS15521.1 - 3.4e-10 40.2 0.0 6e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KXS15521.1 - 1.3e-08 34.9 0.0 1.9e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KXS15521.1 - 1.8e-07 31.2 0.0 2.8e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KXS15521.1 - 2.5e-06 27.4 0.2 5.5e-06 26.3 0.2 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 KXS15521.1 - 0.19 12.5 0.0 0.48 11.2 0.0 1.8 1 1 0 1 1 1 0 Glutathione S-transferase N-terminal domain Reeler PF02014.16 KXS15522.1 - 8e-08 33.1 0.2 1.7e-07 32.1 0.2 1.5 1 0 0 1 1 1 1 Reeler domain Band_7 PF01145.25 KXS15523.1 - 1.4e-13 51.3 0.0 1.4e-13 51.3 0.0 2.2 2 0 0 2 2 2 1 SPFH domain / Band 7 family Band_7 PF01145.25 KXS15524.1 - 8e-12 45.5 0.0 8e-12 45.5 0.0 2.7 3 0 0 3 3 3 1 SPFH domain / Band 7 family Flot PF15975.5 KXS15524.1 - 0.12 12.6 0.1 0.12 12.6 0.1 2.8 2 1 0 2 2 2 0 Flotillin DUF1993 PF09351.10 KXS15524.1 - 0.51 10.5 3.9 0.98 9.5 3.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1993) BTB_2 PF02214.22 KXS15525.1 - 6.1e-06 26.5 0.0 1.3e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain DUF1917 PF08939.10 KXS15527.1 - 1.2e-36 127.0 0.0 3.4e-36 125.5 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF1917) Aldedh PF00171.22 KXS15529.1 - 6.7e-134 446.9 0.1 7.6e-134 446.7 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KXS15529.1 - 0.18 10.8 0.0 0.28 10.2 0.0 1.3 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) Transket_pyr PF02779.24 KXS15530.1 - 2.9e-61 206.3 0.0 6.8e-61 205.0 0.0 1.7 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 KXS15530.1 - 5.5e-58 196.3 0.0 8.4e-58 195.7 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 KXS15530.1 - 1.1e-51 174.5 0.0 1.9e-51 173.8 0.0 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 KXS15530.1 - 9.8e-11 41.1 0.8 2.6e-10 39.7 0.8 1.8 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus Ytp1 PF10355.9 KXS15531.1 - 8.8e-21 74.3 3.6 1.6e-20 73.5 3.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF1295 PF06966.12 KXS15531.1 - 0.083 12.4 0.0 0.083 12.4 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1295) Prion_bPrPp PF11587.8 KXS15531.1 - 0.13 12.2 0.8 0.59 10.0 0.8 2.2 1 0 0 1 1 1 0 Major prion protein bPrPp - N terminal DUF2427 PF10348.9 KXS15531.1 - 2.5 7.9 10.5 0.038 13.8 1.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF2427) Kinesin PF00225.23 KXS15532.1 - 3.5e-54 184.0 0.0 3.8e-29 101.7 0.0 2.1 2 0 0 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 KXS15532.1 - 5e-09 36.2 0.0 1.5e-08 34.7 0.0 1.8 2 0 0 2 2 2 1 Microtubule binding F-box-like PF12937.7 KXS15533.1 - 0.0012 18.7 0.2 0.0029 17.5 0.2 1.7 1 0 0 1 1 1 1 F-box-like Robl_LC7 PF03259.17 KXS15534.1 - 2.2e-05 24.2 0.6 0.33 10.8 0.0 3.1 3 0 0 3 3 3 3 Roadblock/LC7 domain Sdh5 PF03937.16 KXS15535.1 - 9.7e-25 86.3 0.1 1.2e-24 86.0 0.1 1.1 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase adh_short PF00106.25 KXS15536.1 - 6.5e-22 77.9 0.2 5.6e-19 68.4 0.2 2.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXS15536.1 - 3.5e-13 49.7 0.6 2.6e-12 46.8 0.0 2.2 2 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase AMP-binding_C PF13193.6 KXS15537.1 - 3.3e-12 47.2 0.3 4.3e-11 43.6 0.3 2.2 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain Cyclin_N PF00134.23 KXS15538.1 - 5.1e-26 90.9 0.2 9e-26 90.1 0.2 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain DBR1 PF05011.13 KXS15539.1 - 7.9e-32 110.6 0.0 1.1e-31 110.2 0.0 1.2 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.28 KXS15539.1 - 2.1e-09 38.2 0.8 3.4e-09 37.5 0.8 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KXS15539.1 - 0.0044 17.2 0.0 0.012 15.8 0.0 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Glyco_hydro_cc PF11790.8 KXS15540.1 - 1.5e-44 152.4 0.0 2.5e-44 151.6 0.1 1.3 1 1 0 1 1 1 1 Glycosyl hydrolase catalytic core PRIMA1 PF16101.5 KXS15540.1 - 0.32 11.0 4.8 0.61 10.1 4.8 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Glycos_transf_4 PF00953.21 KXS15542.1 - 1.2e-32 113.0 16.4 1.2e-32 113.0 16.4 2.5 3 1 0 3 3 3 1 Glycosyl transferase family 4 Asp5 PF17000.5 KXS15542.1 - 0.016 15.3 2.2 0.026 14.7 0.1 2.5 2 0 0 2 2 2 0 Accessory secretory protein Sec, Asp5 ABC2_membrane PF01061.24 KXS15543.1 - 1.5e-41 142.2 17.2 1.5e-41 142.2 17.2 1.8 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 KXS15543.1 - 1e-28 100.5 0.0 1.5e-28 100.0 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KXS15543.1 - 4.5e-07 30.0 0.6 0.021 14.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 KXS15543.1 - 2.8e-05 23.4 17.2 3.6e-05 23.0 16.6 1.5 1 1 0 1 1 1 1 ABC-2 family transporter protein SMC_N PF02463.19 KXS15543.1 - 6.6e-05 22.5 0.1 0.15 11.4 0.1 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain ABC2_membrane_2 PF12679.7 KXS15543.1 - 0.00074 18.9 1.7 0.00074 18.9 1.7 1.9 1 1 1 2 2 2 1 ABC-2 family transporter protein AAA_23 PF13476.6 KXS15543.1 - 0.0016 19.0 0.1 0.0026 18.3 0.1 1.2 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 KXS15543.1 - 0.017 15.1 0.2 0.031 14.2 0.2 1.3 1 0 0 1 1 1 0 RsgA GTPase NACHT PF05729.12 KXS15543.1 - 0.025 14.5 0.1 0.065 13.1 0.1 1.7 1 0 0 1 1 1 0 NACHT domain AAA_29 PF13555.6 KXS15543.1 - 0.025 14.3 0.1 0.05 13.3 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.6 KXS15543.1 - 0.054 13.1 0.0 0.15 11.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain Sec62 PF03839.16 KXS15544.1 - 8.3e-48 162.8 8.6 5.1e-47 160.2 8.6 1.8 1 1 0 1 1 1 1 Translocation protein Sec62 DnaJ PF00226.31 KXS15545.1 - 0.16 12.1 0.0 0.33 11.1 0.0 1.5 1 0 0 1 1 1 0 DnaJ domain TPMT PF05724.11 KXS15546.1 - 5.3e-47 160.3 0.0 6.3e-47 160.1 0.0 1.0 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) DUF1768 PF08719.11 KXS15548.1 - 6.1e-46 156.6 0.0 7.5e-46 156.3 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Sel1 PF08238.12 KXS15549.1 - 1.2e-106 346.7 47.3 2.3e-10 40.8 0.3 15.7 16 0 0 16 16 16 15 Sel1 repeat TPR_6 PF13174.6 KXS15549.1 - 1.1e-07 32.0 9.6 4.3 8.2 0.0 9.9 13 0 0 13 13 13 2 Tetratricopeptide repeat MgrB PF13998.6 KXS15549.1 - 0.0075 16.1 3.5 21 5.1 0.0 5.5 7 0 0 7 7 7 2 MgrB protein Fib_succ_major PF09603.10 KXS15549.1 - 0.17 12.5 34.7 19 5.8 0.1 8.2 1 1 5 6 6 6 0 Fibrobacter succinogenes major domain (Fib_succ_major) Glug PF07581.12 KXS15549.1 - 0.54 10.8 2.2 56 4.5 0.0 3.5 4 0 0 4 4 4 0 The GLUG motif zf-RING_2 PF13639.6 KXS15550.1 - 1.9e-11 44.1 5.4 2.9e-11 43.5 5.4 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KXS15550.1 - 9.4e-10 38.1 3.0 1.9e-09 37.1 3.0 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KXS15550.1 - 3.1e-09 36.5 6.3 5.5e-09 35.7 6.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXS15550.1 - 7.3e-08 32.2 4.3 1.2e-07 31.5 4.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KXS15550.1 - 2.1e-07 31.1 6.2 9.5e-07 29.0 6.2 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KXS15550.1 - 4.8e-05 23.3 1.9 9.5e-05 22.4 1.9 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 KXS15550.1 - 9.4e-05 22.3 2.7 0.00015 21.6 2.7 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KXS15550.1 - 0.00012 22.0 2.6 0.00021 21.3 0.9 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KXS15550.1 - 0.00031 20.5 2.6 0.00051 19.8 2.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KXS15550.1 - 0.0042 16.9 4.9 0.0093 15.8 4.9 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING-like PF08746.11 KXS15550.1 - 0.018 15.3 1.7 0.028 14.7 1.7 1.3 1 0 0 1 1 1 0 RING-like domain PHD PF00628.29 KXS15550.1 - 0.02 14.8 5.5 0.024 14.5 3.6 2.0 2 0 0 2 2 2 0 PHD-finger Zn_ribbon_17 PF17120.5 KXS15550.1 - 0.057 13.1 3.1 0.1 12.2 3.1 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-HC5HC2H_2 PF13832.6 KXS15550.1 - 0.27 11.4 1.8 0.54 10.4 1.8 1.5 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-RING_4 PF14570.6 KXS15550.1 - 0.56 10.1 3.9 1.1 9.1 3.9 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 KXS15550.1 - 0.97 9.7 4.9 10 6.3 4.9 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain Prok-RING_1 PF14446.6 KXS15550.1 - 1.6 8.7 4.6 3.5 7.6 1.4 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-C3H2C3 PF17122.5 KXS15550.1 - 5 7.3 6.3 12 6.0 6.3 1.8 1 1 0 1 1 1 0 Zinc-finger Nucleopor_Nup85 PF07575.13 KXS15551.1 - 0.00024 19.8 0.0 0.0055 15.3 0.0 2.1 2 0 0 2 2 2 2 Nup85 Nucleoporin Pox_Ag35 PF03286.14 KXS15552.1 - 0.0023 17.7 4.5 0.0026 17.6 4.5 1.0 1 0 0 1 1 1 1 Pox virus Ag35 surface protein RGS PF00615.19 KXS15553.1 - 0.012 15.9 0.0 0.032 14.5 0.0 1.7 1 1 0 1 1 1 0 Regulator of G protein signaling domain DUF3784 PF12650.7 KXS15553.1 - 0.07 13.3 0.4 0.07 13.3 0.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) DUF2207 PF09972.9 KXS15554.1 - 0.3 9.8 0.0 0.46 9.2 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) TMEM154 PF15102.6 KXS15554.1 - 3.1 7.7 9.1 0.12 12.2 1.3 2.5 2 1 0 2 2 2 0 TMEM154 protein family LapA_dom PF06305.11 KXS15554.1 - 5.5 6.9 4.9 10 6.0 0.2 2.3 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain CSTF_C PF14304.6 KXS15555.1 - 0.15 11.6 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 Transcription termination and cleavage factor C-terminal ThrE PF06738.12 KXS15556.1 - 1.4e-39 135.9 20.7 1.5e-21 76.9 0.0 3.1 3 0 0 3 3 3 3 Putative threonine/serine exporter ThrE_2 PF12821.7 KXS15556.1 - 5.5e-14 52.4 15.0 7.3e-12 45.5 6.3 2.5 2 0 0 2 2 2 2 Threonine/Serine exporter, ThrE CarS-like PF01864.17 KXS15556.1 - 2.6 8.0 7.5 8.5 6.3 0.4 3.0 2 1 1 3 3 3 0 CDP-archaeol synthase NAPRTase_N PF17767.1 KXS15558.1 - 1.4e-21 77.2 3.7 2.1e-21 76.6 3.7 1.2 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain 2OG-FeII_Oxy_2 PF13532.6 KXS15561.1 - 0.0037 17.5 0.0 0.0056 16.9 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 KXS15561.1 - 0.005 17.7 0.1 0.094 13.6 0.1 2.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF4381 PF14316.6 KXS15561.1 - 0.043 14.0 0.1 0.073 13.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Gram_pos_anchor PF00746.21 KXS15561.1 - 0.2 11.7 0.8 0.44 10.5 0.8 1.5 1 0 0 1 1 1 0 LPXTG cell wall anchor motif Bap31 PF05529.12 KXS15562.1 - 0.038 13.8 5.7 0.2 11.5 0.1 2.2 2 0 0 2 2 2 0 Bap31/Bap29 transmembrane region LigB PF02900.18 KXS15563.1 - 1.1e-32 113.2 0.0 1.3e-32 112.9 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase NAPRTase PF04095.16 KXS15564.1 - 1.5e-64 217.9 0.0 2e-64 217.5 0.0 1.2 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family NAPRTase_N PF17767.1 KXS15564.1 - 1.8e-30 105.9 0.4 3.1e-30 105.1 0.4 1.4 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain DUF2749 PF10907.8 KXS15565.1 - 2.8 8.2 5.8 4.7 7.5 5.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2749) FeoB_associated PF12669.7 KXS15565.1 - 5.8 7.4 4.7 0.61 10.5 0.9 1.4 2 0 0 2 2 2 0 FeoB-associated Cys-rich membrane protein ThrE PF06738.12 KXS15566.1 - 2.5e-19 69.6 3.4 2.2e-16 60.0 0.0 2.1 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 KXS15566.1 - 0.00021 21.4 1.2 0.00049 20.2 1.2 1.6 1 0 0 1 1 1 1 Threonine/Serine exporter, ThrE FBP_C PF16571.5 KXS15568.1 - 0.3 10.6 2.9 0.42 10.1 2.9 1.2 1 0 0 1 1 1 0 FBP C-terminal treble-clef zinc-finger Pyr_redox_2 PF07992.14 KXS15569.1 - 6.6e-31 107.6 0.0 8.1e-31 107.3 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXS15569.1 - 7.3e-10 38.6 0.0 3.5e-09 36.4 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXS15569.1 - 1.6e-07 31.8 2.2 5.3e-06 26.9 0.7 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KXS15569.1 - 0.00071 18.5 0.8 0.46 9.3 0.2 3.0 2 1 1 3 3 3 2 Tryptophan halogenase Abhydrolase_6 PF12697.7 KXS15569.1 - 0.0024 18.5 1.5 0.0044 17.6 1.5 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lycopene_cycl PF05834.12 KXS15569.1 - 0.014 14.4 0.3 0.077 12.0 0.0 2.2 3 0 0 3 3 3 0 Lycopene cyclase protein K_oxygenase PF13434.6 KXS15569.1 - 0.018 14.2 0.1 0.037 13.2 0.0 1.5 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KXS15569.1 - 0.019 14.6 0.7 0.19 11.3 0.2 2.5 3 0 0 3 3 3 0 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KXS15569.1 - 0.25 10.6 3.0 1.1 8.6 0.2 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase F-box PF00646.33 KXS15570.1 - 0.0012 18.7 0.5 0.0073 16.2 0.2 2.3 2 0 0 2 2 2 1 F-box domain UPF0061 PF02696.14 KXS15571.1 - 2e-103 346.7 0.0 2.9e-103 346.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family RVT_1 PF00078.27 KXS15572.1 - 1.9e-10 40.6 0.0 4.2e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4611 PF15387.6 KXS15572.1 - 1.3 9.3 7.2 4.2 7.7 3.7 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) RXT2_N PF08595.11 KXS15572.1 - 3.6 7.6 4.7 2.5 8.1 1.2 2.2 2 0 0 2 2 2 0 RXT2-like, N-terminal WD40 PF00400.32 KXS15573.1 - 2.3e-07 31.4 0.5 0.0059 17.4 0.0 3.8 3 0 0 3 3 3 2 WD domain, G-beta repeat cNMP_binding PF00027.29 KXS15574.1 - 7e-15 54.9 0.1 1.6e-14 53.8 0.1 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain 7TM_GPCR_Srd PF10317.9 KXS15575.1 - 0.04 13.1 0.3 0.091 11.9 0.3 1.6 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srd DUF389 PF04087.14 KXS15575.1 - 0.07 13.2 0.9 0.57 10.2 0.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF389) DUF2768 PF10966.8 KXS15575.1 - 2.4 8.7 8.1 0.45 11.0 1.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2768) Tail_VII PF17091.5 KXS15576.1 - 0.14 12.0 1.3 0.26 11.2 0.3 1.9 2 0 0 2 2 2 0 Inovirus G7P protein Kelch_5 PF13854.6 KXS15577.1 - 4.3e-25 87.2 0.8 2.9e-07 30.3 0.0 6.6 7 0 0 7 7 7 5 Kelch motif Kelch_4 PF13418.6 KXS15577.1 - 1.2e-24 86.0 5.4 5e-07 29.6 0.0 6.8 6 1 0 6 6 6 3 Galactose oxidase, central domain Kelch_6 PF13964.6 KXS15577.1 - 5.9e-19 67.6 3.3 3.7e-06 27.0 0.1 6.3 4 1 2 6 6 6 3 Kelch motif Kelch_3 PF13415.6 KXS15577.1 - 5.6e-17 61.6 25.1 1.7e-07 31.3 0.0 6.9 8 2 0 8 8 8 3 Galactose oxidase, central domain Kelch_1 PF01344.25 KXS15577.1 - 1.8e-12 46.6 0.0 0.00032 20.2 0.0 5.6 5 0 0 5 5 5 3 Kelch motif Kelch_2 PF07646.15 KXS15577.1 - 6.6e-10 38.6 4.7 0.044 13.8 0.1 6.1 6 0 0 6 6 6 3 Kelch motif 2OG-FeII_Oxy_3 PF13640.6 KXS15578.1 - 0.013 16.4 0.0 0.03 15.2 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Neurochondrin PF05536.11 KXS15586.1 - 2.3e-24 85.7 0.0 4e-24 84.9 0.0 1.4 1 1 0 1 1 1 1 Neurochondrin Sporozoite_P67 PF05642.11 KXS15586.1 - 0.092 10.8 5.3 0.15 10.1 5.3 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Peptidase_M1 PF01433.20 KXS15591.1 - 5.9e-87 290.8 0.5 8.6e-87 290.3 0.5 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 KXS15591.1 - 4.3e-68 230.2 1.8 7.6e-68 229.4 1.8 1.4 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 KXS15591.1 - 3.1e-46 157.9 0.1 5.1e-44 150.7 0.1 2.3 2 0 0 2 2 2 2 Peptidase M1 N-terminal domain Collagen PF01391.18 KXS15591.1 - 1.7e-05 24.5 30.6 4.3e-05 23.2 30.6 1.6 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) TPR_12 PF13424.6 KXS15591.1 - 0.14 12.5 0.0 0.32 11.3 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat Trypan_PARP PF05887.11 KXS15591.1 - 0.39 10.7 9.9 0.79 9.7 9.9 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) TANGO2 PF05742.12 KXS15592.1 - 2.5e-65 221.0 0.0 1.4e-64 218.6 0.0 1.8 1 1 0 1 1 1 1 Transport and Golgi organisation 2 Zn_clus PF00172.18 KXS15593.1 - 6.1e-06 26.3 8.4 8.9e-06 25.7 8.4 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_4 PF13894.6 KXS15594.1 - 4.2e-06 27.2 4.2 0.026 15.4 0.1 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KXS15594.1 - 1.2e-05 25.5 4.9 0.0032 17.8 1.3 2.4 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 KXS15594.1 - 2.5e-05 24.5 5.3 0.021 15.3 0.1 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 KXS15594.1 - 0.017 15.1 0.4 0.017 15.1 0.4 1.8 2 0 0 2 2 2 0 C2H2-type zinc finger Med3 PF11593.8 KXS15594.1 - 1.3 8.1 4.8 2 7.5 4.8 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal ETC_C1_NDUFA5 PF04716.14 KXS15595.1 - 1.5e-28 98.4 0.2 2.2e-28 97.9 0.2 1.3 1 0 0 1 1 1 1 ETC complex I subunit conserved region Homeodomain PF00046.29 KXS15596.1 - 1.6e-11 43.8 0.8 4.6e-11 42.4 0.4 1.8 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 KXS15596.1 - 1.1e-10 41.2 0.2 2.3e-10 40.2 0.2 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.8 KXS15596.1 - 0.013 14.9 0.1 0.024 14.1 0.1 1.3 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez PAP_fibrillin PF04755.12 KXS15596.1 - 0.03 14.2 0.0 0.052 13.5 0.0 1.3 1 0 0 1 1 1 0 PAP_fibrillin DUF1835 PF08874.10 KXS15596.1 - 0.1 12.8 0.1 0.15 12.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1835) bZIP_1 PF00170.21 KXS15597.1 - 7.5e-07 29.2 13.0 1.5e-05 25.0 11.2 2.2 1 1 1 2 2 2 2 bZIP transcription factor DUF4337 PF14235.6 KXS15597.1 - 0.54 10.4 3.2 0.73 9.9 3.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) PCI PF01399.27 KXS15598.1 - 7.3e-06 26.4 0.0 4.2e-05 24.0 0.0 2.2 1 1 0 1 1 1 1 PCI domain Spindle_Spc25 PF08234.12 KXS15600.1 - 2.9e-23 81.9 0.2 5.6e-23 80.9 0.2 1.5 1 0 0 1 1 1 1 Chromosome segregation protein Spc25 FAM184 PF15665.5 KXS15600.1 - 0.0019 18.0 6.6 0.0033 17.2 6.6 1.4 1 0 0 1 1 1 1 Family with sequence similarity 184, A and B ATG16 PF08614.11 KXS15600.1 - 0.011 16.0 9.1 0.022 15.0 9.1 1.5 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DASH_Hsk3 PF08227.11 KXS15600.1 - 0.011 16.0 0.5 0.011 16.0 0.5 2.5 3 0 0 3 3 3 0 DASH complex subunit Hsk3 like Mce4_CUP1 PF11887.8 KXS15600.1 - 0.016 14.7 1.0 0.031 13.7 1.0 1.4 1 0 0 1 1 1 0 Cholesterol uptake porter CUP1 of Mce4, putative DUF2252 PF10009.9 KXS15600.1 - 0.044 12.8 4.0 0.062 12.4 4.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) DUF465 PF04325.13 KXS15600.1 - 0.11 12.6 0.5 0.11 12.6 0.5 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF465) Tweety PF04906.13 KXS15600.1 - 0.13 10.9 1.0 0.19 10.3 1.0 1.2 1 0 0 1 1 1 0 Tweety APG6_N PF17675.1 KXS15600.1 - 0.17 12.4 17.3 0.038 14.5 12.0 2.4 1 1 2 3 3 3 0 Apg6 coiled-coil region Amidinotransf PF02274.17 KXS15600.1 - 0.17 10.9 2.6 0.26 10.3 2.6 1.2 1 0 0 1 1 1 0 Amidinotransferase COG2 PF06148.11 KXS15600.1 - 0.26 11.4 3.1 0.77 9.9 3.1 1.8 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1043 PF06295.12 KXS15600.1 - 0.29 11.1 3.3 0.64 10.0 1.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1043) ZapB PF06005.12 KXS15600.1 - 0.31 11.5 10.0 2.2 8.8 10.0 2.3 1 1 0 1 1 1 0 Cell division protein ZapB CENP-H PF05837.12 KXS15600.1 - 0.45 10.9 7.5 1.1 9.7 7.5 1.6 1 0 0 1 1 1 0 Centromere protein H (CENP-H) TMPIT PF07851.13 KXS15600.1 - 1.4 8.1 3.3 2 7.6 3.3 1.2 1 0 0 1 1 1 0 TMPIT-like protein DivIC PF04977.15 KXS15600.1 - 2.7 7.8 7.6 0.75 9.6 1.5 2.7 1 1 1 2 2 2 0 Septum formation initiator GrpE PF01025.19 KXS15600.1 - 4.4 6.9 10.2 7.2 6.2 8.9 2.0 1 1 1 2 2 2 0 GrpE Spc7 PF08317.11 KXS15600.1 - 10 4.9 14.2 1.5 7.7 3.6 1.8 2 1 1 3 3 3 0 Spc7 kinetochore protein p450 PF00067.22 KXS15601.1 - 9.1e-76 255.5 0.0 1.2e-75 255.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 P2_N PF18628.1 KXS15601.1 - 0.14 11.9 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 Viral coat protein P2 N-terminal domain Tma16 PF11176.8 KXS15601.1 - 0.19 11.6 0.0 0.38 10.6 0.0 1.4 1 0 0 1 1 1 0 Translation machinery-associated protein 16 TPT PF03151.16 KXS15602.1 - 2.9e-17 62.9 9.8 1.7e-09 37.5 3.5 2.1 2 0 0 2 2 2 2 Triose-phosphate Transporter family UAA PF08449.11 KXS15602.1 - 2e-07 30.5 1.6 0.00025 20.4 0.1 2.2 2 0 0 2 2 2 2 UAA transporter family EamA PF00892.20 KXS15602.1 - 7.7e-07 29.4 28.9 2.2e-06 27.9 13.7 2.9 3 0 0 3 3 3 2 EamA-like transporter family PUNUT PF16913.5 KXS15602.1 - 0.007 15.6 11.2 0.27 10.4 0.8 3.1 3 1 0 4 4 4 2 Purine nucleobase transmembrane transport Wzy_C PF04932.15 KXS15602.1 - 0.015 14.9 4.9 0.082 12.5 0.4 3.0 3 0 0 3 3 3 0 O-Antigen ligase SLC35F PF06027.12 KXS15602.1 - 0.017 14.7 2.7 0.049 13.1 0.0 2.2 2 0 0 2 2 2 0 Solute carrier family 35 SRP54 PF00448.22 KXS15603.1 - 3.3e-79 265.1 0.8 5.5e-79 264.4 0.3 1.6 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 KXS15603.1 - 3.8e-30 104.4 2.1 3.8e-30 104.4 2.1 4.7 2 1 2 4 4 3 1 Signal peptide binding domain SRP54_N PF02881.19 KXS15603.1 - 1.6e-19 69.8 3.2 3.9e-19 68.6 3.2 1.7 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.19 KXS15603.1 - 1.3e-06 28.2 0.1 5.6e-06 26.1 0.1 2.0 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CLP1_P PF16575.5 KXS15603.1 - 3.3e-05 23.8 0.1 0.011 15.6 0.0 2.4 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop CbiA PF01656.23 KXS15603.1 - 3.5e-05 23.8 0.0 0.00015 21.8 0.0 2.0 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_33 PF13671.6 KXS15603.1 - 8.4e-05 22.8 0.0 0.00017 21.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain MeaB PF03308.16 KXS15603.1 - 0.00048 19.2 0.0 0.0015 17.6 0.0 1.8 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_17 PF13207.6 KXS15603.1 - 0.00062 20.2 0.1 0.0025 18.2 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KXS15603.1 - 0.00065 19.5 0.0 0.0018 18.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain SRPRB PF09439.10 KXS15603.1 - 0.001 18.6 0.4 1.1 8.7 0.1 2.5 1 1 0 2 2 2 2 Signal recognition particle receptor beta subunit MobB PF03205.14 KXS15603.1 - 0.0012 18.8 0.0 0.0024 17.8 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_31 PF13614.6 KXS15603.1 - 0.0018 18.3 0.0 0.0035 17.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KXS15603.1 - 0.0019 18.5 1.5 0.0078 16.5 0.1 2.6 2 1 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 KXS15603.1 - 0.0019 18.3 0.0 0.0067 16.5 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KXS15603.1 - 0.0032 17.9 0.0 0.011 16.2 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain APS_kinase PF01583.20 KXS15603.1 - 0.0052 16.7 0.1 0.01 15.7 0.1 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase ArsA_ATPase PF02374.15 KXS15603.1 - 0.0064 15.7 0.0 0.0064 15.7 0.0 2.3 3 0 0 3 3 3 1 Anion-transporting ATPase AAA_28 PF13521.6 KXS15603.1 - 0.0079 16.4 0.0 0.014 15.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.17 KXS15603.1 - 0.0089 15.8 0.2 0.043 13.6 0.0 2.3 3 0 0 3 3 3 1 Conserved hypothetical ATP binding protein AAA_18 PF13238.6 KXS15603.1 - 0.0092 16.5 0.0 0.043 14.4 0.0 2.3 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 KXS15603.1 - 0.017 15.2 0.2 0.043 13.8 0.2 1.7 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit MipZ PF09140.11 KXS15603.1 - 0.017 14.4 0.1 0.51 9.6 0.1 2.3 1 1 0 1 1 1 0 ATPase MipZ Thymidylate_kin PF02223.17 KXS15603.1 - 0.02 14.6 0.0 0.07 12.8 0.0 1.9 1 0 0 1 1 1 0 Thymidylate kinase AAA_19 PF13245.6 KXS15603.1 - 0.031 14.6 0.0 0.087 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KXS15603.1 - 0.035 13.4 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA PF00004.29 KXS15603.1 - 0.077 13.4 0.9 0.64 10.4 0.1 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) GTP_EFTU PF00009.27 KXS15603.1 - 0.099 12.2 0.4 0.27 10.8 0.4 1.6 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 KXS15603.1 - 0.11 12.3 0.3 0.7 9.6 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DNA_pol3_chi PF04364.13 KXS15603.1 - 0.13 12.5 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase III chi subunit, HolC SWC7 PF17330.2 KXS15603.1 - 0.13 12.3 0.1 9.3 6.4 0.1 2.4 1 1 1 2 2 2 0 SWR1 chromatin-remodelling complex, sub-unit Swc7 VirC1 PF07015.11 KXS15603.1 - 0.16 11.3 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 VirC1 protein adh_short PF00106.25 KXS15604.1 - 3.4e-44 150.7 1.5 1.9e-43 148.2 1.5 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXS15604.1 - 1.1e-42 146.3 1.9 7.5e-42 143.5 1.9 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXS15604.1 - 1.9e-07 31.1 0.3 4.2e-07 30.0 0.1 1.7 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KXS15604.1 - 0.07 12.6 0.2 0.47 9.9 0.2 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family MFS_1 PF07690.16 KXS15605.1 - 1.3e-07 30.9 5.6 1.4e-07 30.8 5.6 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily She9_MDM33 PF05546.11 KXS15605.1 - 0.067 13.0 1.8 0.09 12.6 1.8 1.2 1 0 0 1 1 1 0 She9 / Mdm33 family MFS_1 PF07690.16 KXS15606.1 - 5.7e-26 91.3 38.6 5.7e-26 91.3 38.6 1.4 1 1 1 2 2 2 2 Major Facilitator Superfamily TPR_2 PF07719.17 KXS15607.1 - 1.4e-35 118.5 4.0 0.0022 18.0 0.0 12.1 12 0 0 12 12 12 8 Tetratricopeptide repeat TPR_1 PF00515.28 KXS15607.1 - 6.4e-32 108.1 7.4 1.1e-06 28.2 0.0 10.8 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_16 PF13432.6 KXS15607.1 - 3.2e-28 98.1 14.1 5e-06 27.0 3.7 7.8 6 2 2 8 8 7 6 Tetratricopeptide repeat TPR_19 PF14559.6 KXS15607.1 - 4.3e-28 97.6 9.2 1.4e-06 28.7 0.0 8.2 5 3 4 9 9 9 6 Tetratricopeptide repeat TPR_7 PF13176.6 KXS15607.1 - 4.2e-24 82.8 4.6 0.00058 19.7 0.0 11.0 11 1 1 12 12 11 5 Tetratricopeptide repeat TPR_8 PF13181.6 KXS15607.1 - 1.3e-22 78.1 0.0 0.038 14.2 0.0 9.8 10 0 0 10 10 8 5 Tetratricopeptide repeat TPR_12 PF13424.6 KXS15607.1 - 3.2e-22 78.6 18.5 1.4e-07 31.7 0.0 8.6 6 4 3 9 9 8 6 Tetratricopeptide repeat TPR_6 PF13174.6 KXS15607.1 - 8e-22 76.4 0.9 0.13 13.0 0.0 10.7 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_11 PF13414.6 KXS15607.1 - 2e-18 65.8 0.1 0.011 15.4 0.0 7.2 6 2 2 8 8 8 4 TPR repeat TPR_14 PF13428.6 KXS15607.1 - 8.5e-17 60.4 21.8 0.18 12.7 0.4 11.7 6 3 7 13 13 12 5 Tetratricopeptide repeat TPR_9 PF13371.6 KXS15607.1 - 1.3e-10 41.3 9.9 0.011 15.8 0.0 6.5 5 1 2 7 7 7 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KXS15607.1 - 2.6e-09 37.1 7.3 2.8 8.3 1.3 6.8 4 1 4 8 8 8 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_MalT PF17874.1 KXS15607.1 - 4.6e-07 29.5 4.7 0.072 12.5 0.0 4.8 3 1 2 5 5 5 2 MalT-like TPR region TPR_21 PF09976.9 KXS15607.1 - 1.7e-06 27.9 5.1 0.0043 16.8 0.8 3.5 3 1 1 4 4 4 2 Tetratricopeptide repeat-like domain TPR_10 PF13374.6 KXS15607.1 - 5.4e-06 26.1 13.5 8.4 6.4 0.0 8.6 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_17 PF13431.6 KXS15607.1 - 3.5e-05 23.9 6.8 5.3 7.6 0.0 7.5 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_4 PF07721.14 KXS15607.1 - 8e-05 22.9 20.2 0.84 10.5 1.4 8.9 11 0 0 11 11 8 2 Tetratricopeptide repeat DUF3856 PF12968.7 KXS15607.1 - 0.0014 18.7 0.6 10 6.2 0.0 4.4 2 2 1 4 4 4 0 Domain of Unknown Function (DUF3856) NARP1 PF12569.8 KXS15607.1 - 0.005 15.8 0.0 2.1 7.1 0.0 3.2 3 1 0 3 3 3 1 NMDA receptor-regulated protein 1 TPR_15 PF13429.6 KXS15607.1 - 0.0052 16.0 0.1 0.31 10.2 0.0 3.3 3 1 1 4 4 4 2 Tetratricopeptide repeat DUF3808 PF10300.9 KXS15607.1 - 0.045 12.5 0.0 0.097 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3808) Cation_ATPase_C PF00689.21 KXS15608.1 - 7.6e-45 152.8 12.5 8.3e-45 152.7 9.5 2.3 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KXS15608.1 - 2.3e-36 125.0 4.0 2.3e-36 125.0 4.0 3.3 4 0 0 4 4 4 1 E1-E2 ATPase Cation_ATPase PF13246.6 KXS15608.1 - 1.3e-18 66.8 0.0 2.6e-18 65.9 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KXS15608.1 - 4.2e-17 63.2 0.2 1.6e-13 51.4 0.1 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KXS15608.1 - 1.2e-10 40.9 0.1 1.1e-08 34.6 0.0 3.0 3 0 0 3 3 3 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KXS15608.1 - 5.5e-06 26.3 1.3 0.00076 19.3 0.7 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase CAMSAP_CKK PF08683.11 KXS15608.1 - 0.032 14.4 0.0 0.074 13.2 0.0 1.5 1 0 0 1 1 1 0 Microtubule-binding calmodulin-regulated spectrin-associated zf-C2H2 PF00096.26 KXS15609.1 - 0.1 13.1 1.0 0.2 12.2 1.0 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXS15609.1 - 0.11 13.4 0.5 0.23 12.4 0.5 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger LIM PF00412.22 KXS15609.1 - 0.2 11.9 0.5 0.35 11.1 0.5 1.3 1 0 0 1 1 1 0 LIM domain zf-C2H2_4 PF13894.6 KXS15610.1 - 0.019 15.8 0.4 0.038 14.8 0.4 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KXS15610.1 - 0.17 12.4 1.1 0.34 11.5 1.1 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type TPR_14 PF13428.6 KXS15613.1 - 0.00054 20.6 1.2 0.55 11.2 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 KXS15613.1 - 0.014 15.9 1.0 1.2 9.7 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat tRNA_int_endo_N PF02778.14 KXS15613.1 - 0.038 13.7 0.1 0.12 12.1 0.0 1.8 2 0 0 2 2 2 0 tRNA intron endonuclease, N-terminal domain TPR_2 PF07719.17 KXS15613.1 - 0.13 12.4 1.5 25 5.3 1.7 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Lipocalin_2 PF08212.12 KXS15614.1 - 4.8e-20 72.0 0.0 5.6e-20 71.8 0.0 1.1 1 0 0 1 1 1 1 Lipocalin-like domain F-box PF00646.33 KXS15615.1 - 6.6e-06 25.9 0.1 6.6e-06 25.9 0.1 2.3 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.7 KXS15615.1 - 5.3e-05 23.0 0.5 5.3e-05 23.0 0.5 2.1 2 0 0 2 2 2 1 F-box-like F-box_4 PF15966.5 KXS15615.1 - 0.0032 17.4 0.8 0.0041 17.0 0.1 1.6 2 0 0 2 2 2 1 F-box RRM_1 PF00076.22 KXS15617.1 - 1.6e-12 47.0 0.3 2.5e-12 46.4 0.3 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RSRP PF17069.5 KXS15617.1 - 1.8 8.1 52.2 2.2 7.8 52.2 1.2 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 Rbsn PF11464.8 KXS15618.1 - 0.017 14.9 1.7 0.04 13.6 0.0 2.3 2 1 0 2 2 2 0 Rabenosyn Rab binding domain TIMELESS PF04821.14 KXS15619.1 - 3.6e-68 229.8 0.0 3.6e-68 229.8 0.0 2.4 3 0 0 3 3 3 1 Timeless protein TIMELESS_C PF05029.13 KXS15619.1 - 9e-11 41.6 0.1 9e-11 41.6 0.1 4.0 4 1 0 4 4 4 1 Timeless protein C terminal region FAD_binding_7 PF03441.14 KXS15620.1 - 3.6e-38 131.1 0.9 2e-37 128.6 0.9 2.0 1 1 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 KXS15620.1 - 3.5e-10 40.1 0.0 2.9e-09 37.1 0.0 2.5 2 1 0 2 2 2 1 DNA photolyase PEMT PF04191.13 KXS15621.1 - 2.3e-28 98.7 1.3 4.6e-28 97.7 1.3 1.4 1 0 0 1 1 1 1 Phospholipid methyltransferase ICMT PF04140.14 KXS15621.1 - 0.026 14.9 0.2 0.07 13.6 0.2 1.8 1 1 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family RVT_1 PF00078.27 KXS15622.1 - 5.8e-11 42.3 0.0 1.1e-10 41.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Glyco_hydro_7 PF00840.20 KXS15623.1 - 4.6e-30 104.7 11.5 5.3e-18 65.0 2.2 4.1 1 1 1 2 2 2 2 Glycosyl hydrolase family 7 Pyr_redox_2 PF07992.14 KXS15624.1 - 4.5e-34 118.0 0.0 5.9e-34 117.6 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXS15624.1 - 3.6e-12 46.7 3.2 2.5e-11 43.9 1.6 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXS15624.1 - 1.7e-07 30.8 0.1 4.6e-07 29.4 0.0 1.6 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXS15624.1 - 8.3e-07 28.9 4.5 0.21 11.1 0.0 3.3 2 1 1 3 3 3 3 FAD dependent oxidoreductase K_oxygenase PF13434.6 KXS15624.1 - 1.8e-05 24.1 0.2 6.6e-05 22.2 0.1 1.8 1 1 1 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KXS15624.1 - 0.0012 18.8 2.4 5.8 6.9 0.2 3.4 2 1 1 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KXS15624.1 - 0.002 18.3 1.7 1.7 8.9 0.1 2.4 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 KXS15624.1 - 0.0024 16.8 1.6 0.84 8.4 0.4 3.0 2 1 1 3 3 3 1 Tryptophan halogenase Lycopene_cycl PF05834.12 KXS15624.1 - 0.016 14.3 0.1 0.071 12.2 0.0 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_binding_3 PF01494.19 KXS15624.1 - 0.02 14.2 2.3 2.2 7.4 0.0 2.8 2 1 1 3 3 3 0 FAD binding domain FAD_oxidored PF12831.7 KXS15624.1 - 0.033 13.5 1.3 2.5 7.4 0.0 3.0 3 0 0 3 3 3 0 FAD dependent oxidoreductase Thi4 PF01946.17 KXS15624.1 - 0.045 13.0 0.4 0.22 10.7 0.1 2.0 2 0 0 2 2 2 0 Thi4 family FAD_binding_2 PF00890.24 KXS15624.1 - 0.14 11.2 2.2 1.7 7.7 0.5 2.7 2 1 2 4 4 4 0 FAD binding domain TrkA_N PF02254.18 KXS15624.1 - 0.15 12.4 0.9 0.6 10.4 0.3 2.3 2 0 0 2 2 2 0 TrkA-N domain HI0933_like PF03486.14 KXS15624.1 - 0.68 8.6 2.5 4.4 5.9 0.2 2.8 2 1 1 3 3 3 0 HI0933-like protein DUF5419 PF17441.2 KXS15625.1 - 0.17 12.0 4.9 2.2 8.4 0.9 2.4 1 1 1 2 2 2 0 Family of unknown function (DUF5419) Glyco_hydro_7 PF00840.20 KXS15626.1 - 9.3e-26 90.5 9.2 2.1e-19 69.6 1.9 4.1 1 1 1 3 3 3 2 Glycosyl hydrolase family 7 TFIIA PF03153.13 KXS15626.1 - 0.75 9.7 36.6 1.3 8.9 36.6 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Trypsin PF00089.26 KXS15627.1 - 1.2e-24 87.3 2.1 2e-24 86.6 2.1 1.3 1 0 0 1 1 1 1 Trypsin Amidohydro_3 PF07969.11 KXS15629.1 - 6.5e-75 253.4 1.4 7.7e-75 253.2 1.4 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 KXS15629.1 - 2.9e-19 69.6 0.0 9.2e-16 58.1 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Sel1 PF08238.12 KXS15630.1 - 4.5e-15 55.7 7.1 0.00014 22.4 0.3 3.6 3 0 0 3 3 3 3 Sel1 repeat V-SNARE PF05008.15 KXS15631.1 - 1.2e-16 60.8 6.2 1.2e-16 60.8 6.2 1.8 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.8 KXS15631.1 - 2.4e-14 53.4 7.9 1.1e-13 51.2 4.0 2.6 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Fusion_gly PF00523.18 KXS15631.1 - 0.00076 17.8 2.4 0.0054 15.0 0.3 2.0 2 0 0 2 2 2 1 Fusion glycoprotein F0 Sec20 PF03908.13 KXS15631.1 - 0.0014 18.5 5.4 0.0084 16.0 0.1 2.8 2 1 1 3 3 3 1 Sec20 Synaptobrevin PF00957.21 KXS15631.1 - 0.0032 17.2 0.8 0.0032 17.2 0.8 2.4 2 1 0 2 2 2 1 Synaptobrevin DUF745 PF05335.13 KXS15631.1 - 0.017 14.8 8.3 0.036 13.8 2.5 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF745) Fez1 PF06818.15 KXS15631.1 - 0.05 14.1 3.8 0.065 13.7 3.8 1.3 1 1 0 1 1 1 0 Fez1 IL11 PF07400.11 KXS15631.1 - 0.065 12.9 1.1 3.9 7.1 0.1 2.5 1 1 1 2 2 2 0 Interleukin 11 SPW PF03779.14 KXS15631.1 - 0.078 12.6 0.6 0.13 11.9 0.6 1.3 1 0 0 1 1 1 0 SPW repeat Macoilin PF09726.9 KXS15631.1 - 0.14 10.7 1.5 0.19 10.2 1.5 1.1 1 0 0 1 1 1 0 Macoilin family FAM76 PF16046.5 KXS15631.1 - 0.15 11.4 6.7 0.022 14.1 2.8 1.5 2 0 0 2 2 2 0 FAM76 protein Muted PF14942.6 KXS15631.1 - 0.19 12.0 5.2 0.089 13.1 2.8 1.6 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein Exonuc_VII_L PF02601.15 KXS15631.1 - 0.21 11.1 10.6 1.5 8.3 10.6 1.9 1 1 0 1 1 1 0 Exonuclease VII, large subunit Nbl1_Borealin_N PF10444.9 KXS15631.1 - 0.26 11.0 6.1 1.6 8.4 2.5 3.1 1 1 1 2 2 2 0 Nbl1 / Borealin N terminal Laminin_II PF06009.12 KXS15631.1 - 0.47 10.5 6.5 0.48 10.4 3.2 2.3 2 1 0 2 2 2 0 Laminin Domain II DUF16 PF01519.16 KXS15631.1 - 0.56 10.7 3.6 0.38 11.2 1.2 1.8 2 0 0 2 2 2 0 Protein of unknown function DUF16 DUF1664 PF07889.12 KXS15631.1 - 1.9 8.5 5.0 2.1 8.4 0.9 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) OmpH PF03938.14 KXS15631.1 - 3.3 8.0 8.0 55 4.1 8.0 2.6 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) TMEM135_C_rich PF15982.5 KXS15632.1 - 0.00011 22.8 1.6 0.0084 16.7 0.2 3.0 3 0 0 3 3 3 1 N-terminal cysteine-rich region of Transmembrane protein 135 Piwi PF02171.17 KXS15633.1 - 2.6e-68 230.5 0.0 3.4e-68 230.1 0.0 1.1 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 KXS15633.1 - 3.2e-06 27.8 0.0 6.8e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of argonaute PAZ PF02170.22 KXS15633.1 - 0.0004 20.2 0.0 0.00077 19.3 0.0 1.4 1 0 0 1 1 1 1 PAZ domain ArgoL2 PF16488.5 KXS15633.1 - 0.0013 19.0 0.0 0.0038 17.5 0.0 1.8 1 0 0 1 1 1 1 Argonaute linker 2 domain DUF4061 PF13270.6 KXS15634.1 - 0.22 11.8 0.0 3.7 7.9 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4061) Dehydrin PF00257.19 KXS15636.1 - 0.54 10.8 4.2 1.1 9.8 4.2 1.5 1 0 0 1 1 1 0 Dehydrin Mito_carr PF00153.27 KXS15637.1 - 1e-56 188.8 0.4 3.2e-18 65.4 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein PHO4 PF01384.20 KXS15638.1 - 1.3e-86 290.7 20.0 1.5e-86 290.5 20.0 1.1 1 0 0 1 1 1 1 Phosphate transporter family CrtC PF07143.11 KXS15639.1 - 0.00018 22.2 0.7 0.00062 20.5 0.7 1.9 1 1 0 1 1 1 1 CrtC N-terminal lipocalin domain DDE_Tnp_4 PF13359.6 KXS15640.1 - 0.00014 21.6 0.0 0.00015 21.4 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease p450 PF00067.22 KXS15642.1 - 2e-63 214.7 0.0 2.7e-63 214.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DHNA PF04038.12 KXS15642.1 - 0.062 13.8 0.1 10 6.7 0.1 2.3 2 0 0 2 2 2 0 Dihydroneopterin aldolase Myb_DNA-bind_7 PF15963.5 KXS15643.1 - 5.4e-26 90.3 0.3 8.7e-26 89.7 0.3 1.3 1 0 0 1 1 1 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 KXS15643.1 - 6.2e-06 26.3 0.0 5.2e-05 23.3 0.0 2.4 1 1 1 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KXS15643.1 - 0.025 14.8 0.0 0.083 13.2 0.0 1.8 1 1 1 2 2 2 0 Myb-like DNA-binding domain Tankyrase_bdg_C PF15327.6 KXS15643.1 - 0.034 14.6 0.7 0.045 14.2 0.1 1.5 2 0 0 2 2 2 0 Tankyrase binding protein C terminal domain F-box-like PF12937.7 KXS15644.1 - 2.3e-05 24.2 0.6 5.2e-05 23.0 0.6 1.6 1 0 0 1 1 1 1 F-box-like HeH PF12949.7 KXS15645.1 - 0.096 12.4 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 HeH/LEM domain Ank_4 PF13637.6 KXS15646.1 - 7.1e-06 26.5 0.0 0.076 13.6 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeats (many copies) SH3_9 PF14604.6 KXS15646.1 - 1.8e-05 24.5 0.0 4.4e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXS15646.1 - 2.5e-05 23.8 0.2 8.1e-05 22.1 0.0 1.9 2 0 0 2 2 2 1 SH3 domain Ank PF00023.30 KXS15646.1 - 7.7e-05 23.0 1.0 0.63 10.6 0.0 4.2 5 0 0 5 5 4 1 Ankyrin repeat Ank_3 PF13606.6 KXS15646.1 - 0.00049 20.3 0.0 2.1 9.2 0.0 3.7 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.7 KXS15646.1 - 0.0012 19.4 0.0 0.4 11.3 0.0 3.3 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) bZIP_1 PF00170.21 KXS15646.1 - 0.015 15.4 2.2 0.023 14.8 0.3 2.0 1 1 1 2 2 2 0 bZIP transcription factor CENP-F_leu_zip PF10473.9 KXS15646.1 - 0.017 15.2 1.2 0.03 14.3 1.2 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6_N PF17675.1 KXS15646.1 - 0.017 15.6 0.1 0.031 14.8 0.1 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region ATG16 PF08614.11 KXS15646.1 - 0.024 14.9 1.4 0.045 14.0 1.4 1.4 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) YabA PF06156.13 KXS15646.1 - 0.031 14.9 0.3 0.056 14.1 0.3 1.4 1 0 0 1 1 1 0 Initiation control protein YabA JIP_LZII PF16471.5 KXS15646.1 - 0.07 13.3 2.0 0.16 12.2 0.7 2.2 3 0 0 3 3 3 0 JNK-interacting protein leucine zipper II ZapB PF06005.12 KXS15646.1 - 0.17 12.3 5.5 0.27 11.7 1.4 2.2 1 1 1 2 2 2 0 Cell division protein ZapB TolA_bind_tri PF16331.5 KXS15646.1 - 1.8 8.7 5.4 2.8 8.1 4.5 1.7 1 1 1 2 2 2 0 TolA binding protein trimerisation TMF_TATA_bd PF12325.8 KXS15646.1 - 2.6 8.3 5.0 1.3 9.3 2.0 1.8 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding bZIP_2 PF07716.15 KXS15646.1 - 6.2 7.0 5.3 52 4.0 2.2 2.4 2 0 0 2 2 2 0 Basic region leucine zipper zf-RING_2 PF13639.6 KXS15647.1 - 2.4e-13 50.2 5.5 3.6e-13 49.6 5.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KXS15647.1 - 1.9e-11 43.5 2.5 3.5e-11 42.6 2.5 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KXS15647.1 - 3.2e-10 39.7 5.4 5.3e-10 39.0 5.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXS15647.1 - 6.3e-10 38.8 5.2 9.5e-10 38.2 5.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KXS15647.1 - 4e-09 36.6 3.2 7.6e-09 35.7 3.2 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KXS15647.1 - 1.4e-07 31.4 3.7 2e-07 30.9 3.7 1.2 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KXS15647.1 - 2.6e-06 27.4 1.8 3.1e-06 27.1 0.7 1.8 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KXS15647.1 - 0.00016 21.5 3.0 0.00024 20.9 3.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KXS15647.1 - 0.00032 20.5 3.0 0.00059 19.6 3.0 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KXS15647.1 - 0.0011 18.9 0.7 0.002 18.1 0.7 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 KXS15647.1 - 0.0091 15.6 4.6 0.048 13.3 5.1 1.8 1 1 1 2 2 2 1 Zinc-ribbon, C4HC2 type RINGv PF12906.7 KXS15647.1 - 0.027 14.6 2.9 0.058 13.5 2.9 1.6 1 1 0 1 1 1 0 RING-variant domain zf-C3HC4_4 PF15227.6 KXS15647.1 - 0.081 13.1 3.1 0.23 11.6 3.1 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 KXS15647.1 - 0.23 11.7 5.5 0.96 9.7 5.5 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain Zf_RING PF16744.5 KXS15647.1 - 0.25 11.5 2.4 0.46 10.6 2.4 1.5 1 0 0 1 1 1 0 KIAA1045 RING finger zf-RING_4 PF14570.6 KXS15647.1 - 0.63 9.9 4.3 1 9.2 4.3 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.29 KXS15647.1 - 0.73 9.8 4.9 1.3 8.9 4.9 1.5 1 1 0 1 1 1 0 PHD-finger Peptidase_M13_N PF05649.13 KXS15649.1 - 0.0033 17.2 0.0 0.0036 17.0 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13_N PF05649.13 KXS15650.1 - 1.3e-16 61.3 0.0 1.9e-16 60.7 0.0 1.3 1 1 0 1 1 1 1 Peptidase family M13 3-HAO PF06052.12 KXS15653.1 - 6.5e-63 210.9 0.0 7.3e-63 210.7 0.0 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.11 KXS15653.1 - 3.2e-07 30.0 0.0 5.4e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_4 PF08007.12 KXS15653.1 - 0.00014 21.5 0.0 0.00017 21.1 0.0 1.1 1 0 0 1 1 1 1 Cupin superfamily protein DZR PF12773.7 KXS15653.1 - 0.00034 20.6 1.8 0.00054 19.9 1.8 1.3 1 0 0 1 1 1 1 Double zinc ribbon Cupin_1 PF00190.22 KXS15653.1 - 0.0004 20.0 0.0 0.00054 19.6 0.0 1.2 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.19 KXS15653.1 - 0.00049 20.0 0.0 0.00084 19.3 0.0 1.4 1 0 0 1 1 1 1 AraC-like ligand binding domain Zn_Tnp_IS1595 PF12760.7 KXS15653.1 - 0.004 17.1 4.6 0.015 15.2 1.0 2.3 2 0 0 2 2 2 1 Transposase zinc-ribbon domain Cupin_3 PF05899.12 KXS15653.1 - 0.0084 15.8 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF861) zf-ACC PF17848.1 KXS15653.1 - 0.027 14.5 1.6 1.5 8.9 0.1 2.3 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain ARD PF03079.14 KXS15653.1 - 0.037 14.2 0.0 0.055 13.6 0.0 1.2 1 0 0 1 1 1 0 ARD/ARD' family Zn-ribbon_8 PF09723.10 KXS15653.1 - 0.066 13.3 2.0 0.25 11.5 2.0 2.0 1 1 0 1 1 1 0 Zinc ribbon domain zinc_ribbon_15 PF17032.5 KXS15653.1 - 0.066 14.0 0.3 1.4 9.7 0.1 2.1 2 0 0 2 2 2 0 zinc-ribbon family zinc_ribbon_2 PF13240.6 KXS15653.1 - 0.067 12.9 1.8 0.45 10.3 0.3 2.6 2 0 0 2 2 2 0 zinc-ribbon domain zf-TFIIB PF13453.6 KXS15653.1 - 0.17 11.2 1.3 10 5.6 0.1 2.5 2 0 0 2 2 2 0 Transcription factor zinc-finger zf-ribbon_3 PF13248.6 KXS15653.1 - 0.36 10.3 2.6 0.31 10.5 0.3 2.0 2 0 0 2 2 2 0 zinc-ribbon domain Nudix_N_2 PF14803.6 KXS15653.1 - 0.49 10.4 6.9 1.9 8.5 0.3 2.7 2 1 0 2 2 2 0 Nudix N-terminal RmlD_sub_bind PF04321.17 KXS15654.1 - 4e-61 206.6 0.0 5.1e-61 206.3 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 KXS15654.1 - 5.2e-23 81.7 0.0 7.2e-23 81.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KXS15654.1 - 1.6e-08 34.1 0.3 2e-06 27.2 0.0 2.7 1 1 1 2 2 2 2 Male sterility protein GDP_Man_Dehyd PF16363.5 KXS15654.1 - 3.8e-08 33.1 0.0 5.7e-08 32.5 0.0 1.3 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KXS15654.1 - 8.1e-08 31.7 0.2 5.9e-06 25.6 0.2 2.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 KXS15654.1 - 0.00051 19.1 0.0 0.0023 17.0 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family PUA PF01472.20 KXS15654.1 - 0.1 12.5 0.1 1.4 9.0 0.0 2.3 2 0 0 2 2 2 0 PUA domain Sporozoite_P67 PF05642.11 KXS15655.1 - 0.19 9.7 1.6 0.22 9.6 1.6 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DNA_pol_phi PF04931.13 KXS15655.1 - 0.24 9.5 2.8 0.28 9.2 2.8 1.2 1 0 0 1 1 1 0 DNA polymerase phi Cwf_Cwc_15 PF04889.12 KXS15655.1 - 1.7 8.3 6.5 2.7 7.7 6.5 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Pkinase PF00069.25 KXS15656.1 - 1.9e-20 73.3 0.0 2.4e-20 73.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS15656.1 - 0.00021 20.7 0.0 0.00027 20.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RCC1 PF00415.18 KXS15659.1 - 1.4e-22 80.1 23.2 0.00056 20.5 0.0 7.8 7 1 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KXS15659.1 - 1.7e-06 27.7 35.8 0.32 10.9 0.2 9.7 9 2 0 9 9 9 5 Regulator of chromosome condensation (RCC1) repeat SRP-alpha_N PF04086.13 KXS15660.1 - 1.9 8.3 18.1 2.8 7.8 18.1 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal SNF2_N PF00176.23 KXS15661.1 - 5e-39 134.0 0.1 1.6e-38 132.3 0.1 1.8 1 1 1 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KXS15661.1 - 3.9e-18 65.8 0.7 2.1e-17 63.4 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain HSA PF07529.13 KXS15661.1 - 1.9e-09 37.7 9.0 5.8e-09 36.2 9.0 1.9 1 0 0 1 1 1 1 HSA ResIII PF04851.15 KXS15661.1 - 0.016 15.2 0.0 0.044 13.8 0.0 1.7 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DUF1027 PF06265.11 KXS15661.1 - 0.14 12.1 0.0 1.5 8.9 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1027) ABC2_membrane PF01061.24 KXS15662.1 - 1.1e-64 217.7 44.7 9e-41 139.6 15.6 2.5 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 KXS15662.1 - 3.5e-29 102.1 0.0 6e-17 62.5 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KXS15662.1 - 4.9e-14 52.0 3.1 4.3e-12 45.8 0.0 3.8 4 0 0 4 4 4 1 CDR ABC transporter ABC2_membrane_3 PF12698.7 KXS15662.1 - 0.0003 20.0 12.1 0.0003 20.0 12.1 3.4 2 2 1 3 3 3 1 ABC-2 family transporter protein AAA_21 PF13304.6 KXS15662.1 - 0.0019 18.1 0.0 0.0075 16.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KXS15662.1 - 0.0077 16.1 0.0 0.018 14.9 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 KXS15662.1 - 0.0088 16.4 0.1 0.24 11.8 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KXS15662.1 - 0.091 13.0 0.2 0.5 10.6 0.2 2.3 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KXS15662.1 - 0.15 11.8 0.1 1.6 8.6 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain PQ-loop PF04193.14 KXS15665.1 - 1e-28 98.8 17.7 6.3e-16 57.9 2.0 3.1 3 0 0 3 3 3 2 PQ loop repeat Fungal_trans PF04082.18 KXS15666.1 - 4.8e-07 29.1 3.2 5.7e-07 28.8 3.2 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain TIP120 PF08623.10 KXS15666.1 - 0.16 11.8 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 TATA-binding protein interacting (TIP20) DUF4449 PF14613.6 KXS15670.1 - 1.2e-08 35.2 0.3 1.2e-08 35.2 0.3 3.8 3 1 1 4 4 4 1 Protein of unknown function (DUF4449) Com_YlbF PF06133.11 KXS15670.1 - 0.0046 17.6 0.7 0.047 14.3 0.2 2.8 2 0 0 2 2 2 1 Control of competence regulator ComK, YlbF/YmcA Collagen_mid PF15984.5 KXS15670.1 - 0.053 13.3 1.5 0.13 12.0 0.0 2.3 3 0 0 3 3 3 0 Bacterial collagen, middle region GTA_holin_3TM PF11351.8 KXS15670.1 - 3.5 8.2 4.7 1.3 9.6 0.1 2.8 3 0 0 3 3 3 0 Holin of 3TMs, for gene-transfer release DUF4449 PF14613.6 KXS15672.1 - 1.9e-08 34.6 0.0 1.9e-08 34.6 0.0 4.8 3 2 1 4 4 4 1 Protein of unknown function (DUF4449) ARTD15_N PF18084.1 KXS15672.1 - 0.068 13.4 0.1 0.25 11.6 0.1 2.0 1 0 0 1 1 1 0 ARTD15 N-terminal domain DUF4148 PF13663.6 KXS15672.1 - 0.24 11.6 1.2 0.72 10.1 1.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) Nif11 PF07862.11 KXS15672.1 - 0.48 10.8 6.5 0.7 10.2 0.0 4.1 4 1 0 4 4 4 0 Nif11 domain CCDC-167 PF15188.6 KXS15672.1 - 1.1 9.6 3.8 1.9 8.9 0.1 3.4 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 DUF4085 PF13315.6 KXS15672.1 - 4.2 6.9 6.6 11 5.6 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF4085) adh_short PF00106.25 KXS15673.1 - 6.5e-25 87.7 0.6 8.5e-19 67.8 0.0 2.2 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXS15673.1 - 3.2e-14 53.1 0.2 7.1e-12 45.4 0.0 2.2 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase SH3_9 PF14604.6 KXS15674.1 - 9.3e-07 28.6 0.5 2e-06 27.6 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 KXS15674.1 - 2.7e-05 23.7 0.0 4.6e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 SH3 domain TFIIIC_sub6 PF10419.9 KXS15675.1 - 6.5e-14 51.6 0.0 1e-13 50.9 0.0 1.3 1 0 0 1 1 1 1 TFIIIC subunit triple barrel domain PCI PF01399.27 KXS15676.1 - 8.8e-12 45.5 0.0 1.7e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 PCI domain Pkinase PF00069.25 KXS15678.1 - 3.8e-56 190.4 0.0 4.9e-56 190.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS15678.1 - 5.8e-22 78.2 0.0 7.4e-22 77.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 KXS15678.1 - 0.00082 19.1 0.0 0.2 11.3 0.0 2.1 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 KXS15678.1 - 0.027 13.8 0.1 0.19 11.1 0.0 2.0 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family SRP-alpha_N PF04086.13 KXS15680.1 - 0.75 9.7 4.2 1.1 9.1 4.2 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Aldo_ket_red PF00248.21 KXS15681.1 - 1.8e-64 217.7 0.0 2.3e-64 217.4 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 KXS15682.1 - 3.7e-74 249.6 0.0 4.2e-74 249.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 KXS15683.1 - 2.4e-26 92.6 0.0 9.1e-20 71.0 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family zf-RING_2 PF13639.6 KXS15685.1 - 2.6e-08 34.0 0.9 8.4e-08 32.4 0.9 2.0 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KXS15685.1 - 6.4e-08 32.2 1.0 1.4e-07 31.1 1.0 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 KXS15685.1 - 2.1e-07 30.8 1.2 5.4e-07 29.5 1.2 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KXS15685.1 - 8.3e-07 28.7 0.8 2.5e-06 27.2 0.8 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXS15685.1 - 1.2e-05 25.0 0.2 3e-05 23.8 0.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KXS15685.1 - 3.2e-05 23.5 0.6 8e-05 22.2 0.6 1.7 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-rbx1 PF12678.7 KXS15685.1 - 0.003 17.8 5.9 0.026 14.8 5.9 2.4 1 1 1 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 KXS15685.1 - 0.0095 16.1 0.9 0.025 14.7 0.9 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 KXS15685.1 - 0.051 13.5 2.9 0.35 10.9 2.9 2.4 1 1 1 2 2 2 0 zinc-RING finger domain FANCL_C PF11793.8 KXS15685.1 - 0.062 13.5 2.0 0.2 11.8 2.0 1.8 1 1 1 2 2 2 0 FANCL C-terminal domain zf-ANAPC11 PF12861.7 KXS15685.1 - 0.59 10.2 5.4 0.39 10.8 2.2 2.2 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3H2C3 PF17122.5 KXS15685.1 - 2.6 8.1 7.5 1.9 8.6 4.5 2.4 2 1 0 2 2 2 0 Zinc-finger zf-RING_2 PF13639.6 KXS15686.1 - 1.2e-12 47.9 3.0 1.8e-12 47.4 3.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KXS15686.1 - 1.8e-09 37.5 0.9 4.9e-08 32.9 0.3 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KXS15686.1 - 2.3e-09 36.9 2.7 3.9e-09 36.2 2.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KXS15686.1 - 1.4e-08 34.3 1.1 1.4e-08 34.3 1.1 1.6 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 KXS15686.1 - 1.6e-07 31.0 0.6 2.5e-07 30.5 0.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KXS15686.1 - 4.3e-07 30.1 4.9 6.7e-06 26.3 6.2 2.2 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 KXS15686.1 - 4.1e-06 26.6 1.0 6.2e-06 26.0 1.0 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KXS15686.1 - 5.4e-06 26.2 3.9 0.00016 21.5 0.3 2.2 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KXS15686.1 - 6.8e-06 26.0 0.4 1.1e-05 25.2 0.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 KXS15686.1 - 0.00011 22.2 0.9 0.00024 21.1 0.9 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 KXS15686.1 - 0.00013 22.1 1.1 0.00037 20.6 1.3 1.7 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING Zn_ribbon_17 PF17120.5 KXS15686.1 - 0.00034 20.2 2.2 0.00057 19.5 2.2 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type TackOD1 PF18551.1 KXS15686.1 - 0.018 14.7 0.1 0.026 14.2 0.1 1.1 1 0 0 1 1 1 0 Thaumarchaeal output domain 1 zf-RING_4 PF14570.6 KXS15686.1 - 0.018 14.8 1.1 0.028 14.2 1.1 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Nse PF11789.8 KXS15686.1 - 0.029 14.2 0.2 0.051 13.4 0.2 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Rad50_zn_hook PF04423.14 KXS15686.1 - 0.031 14.1 1.9 0.15 12.0 0.4 2.1 2 0 0 2 2 2 0 Rad50 zinc hook motif DUF1272 PF06906.11 KXS15686.1 - 0.044 13.9 0.3 0.075 13.1 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) FANCL_C PF11793.8 KXS15686.1 - 0.11 12.7 3.6 1.4 9.1 3.6 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain Prok-RING_1 PF14446.6 KXS15686.1 - 0.18 11.8 1.6 6.2 6.8 0.2 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 PHD PF00628.29 KXS15686.1 - 0.19 11.7 1.3 0.99 9.4 1.4 2.0 1 1 1 2 2 2 0 PHD-finger Vps39_2 PF10367.9 KXS15686.1 - 0.23 11.9 0.4 1.4 9.4 0.1 2.1 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 zf-C3H2C3 PF17122.5 KXS15686.1 - 0.92 9.6 7.8 0.16 12.0 2.8 2.1 2 1 0 2 2 2 0 Zinc-finger zf-RING_2 PF13639.6 KXS15687.1 - 3.1e-09 37.0 1.8 3.1e-09 37.0 1.8 1.6 2 0 0 2 2 1 1 Ring finger domain zf-RING_11 PF17123.5 KXS15687.1 - 5.7e-08 32.4 1.8 1.3e-07 31.3 1.8 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KXS15687.1 - 1.6e-07 31.0 1.7 1.6e-07 31.0 1.7 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXS15687.1 - 4.6e-07 29.8 1.1 1.1e-06 28.5 1.1 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KXS15687.1 - 2.9e-06 27.1 0.3 6.5e-06 25.9 0.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KXS15687.1 - 2.7e-05 24.4 4.9 0.0002 21.6 5.2 2.1 1 1 1 2 2 2 1 RING-H2 zinc finger domain Zn_ribbon_17 PF17120.5 KXS15687.1 - 0.00079 19.0 0.9 0.0016 18.0 0.9 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 KXS15687.1 - 0.0025 17.9 1.4 0.0047 17.1 1.4 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 KXS15687.1 - 0.0029 17.5 0.2 0.0067 16.4 0.2 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 KXS15687.1 - 0.0082 16.2 1.8 0.022 14.8 1.8 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 KXS15687.1 - 0.012 15.5 0.3 0.024 14.5 0.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KXS15687.1 - 8.7 6.3 9.0 2.6 8.0 1.8 2.9 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KXS15688.1 - 1.6e-11 44.3 4.9 2.6e-11 43.7 4.9 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KXS15688.1 - 3e-09 36.7 3.1 1.1e-08 34.9 0.7 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_11 PF17123.5 KXS15688.1 - 6.5e-09 35.4 1.7 6.5e-09 35.4 1.7 1.7 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KXS15688.1 - 1.8e-08 34.1 4.0 3e-08 33.3 4.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXS15688.1 - 1.2e-07 31.5 1.7 1.8e-07 30.9 1.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KXS15688.1 - 2.6e-06 27.6 7.2 1.2e-05 25.5 7.4 2.0 1 1 1 2 2 2 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KXS15688.1 - 7.8e-06 25.8 0.9 1.2e-05 25.2 0.9 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KXS15688.1 - 2e-05 24.3 1.8 3.1e-05 23.7 1.8 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KXS15688.1 - 0.00019 21.2 5.5 0.0015 18.3 5.3 2.1 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KXS15688.1 - 0.00044 20.2 2.9 0.0014 18.7 2.9 1.8 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 KXS15688.1 - 0.00058 20.0 2.4 0.0011 19.1 2.4 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Zn_ribbon_17 PF17120.5 KXS15688.1 - 0.0012 18.4 2.7 0.002 17.7 2.7 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 KXS15688.1 - 0.01 15.6 1.2 0.015 15.1 1.2 1.2 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.29 KXS15688.1 - 0.17 11.8 1.3 0.53 10.2 1.3 1.8 1 1 1 2 2 2 0 PHD-finger zf-Nse PF11789.8 KXS15688.1 - 0.18 11.6 1.4 0.33 10.8 1.4 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Rad50_zn_hook PF04423.14 KXS15688.1 - 0.18 11.6 0.2 0.18 11.6 0.2 1.7 2 0 0 2 2 2 0 Rad50 zinc hook motif DNA_ligase_ZBD PF03119.16 KXS15688.1 - 0.54 10.3 2.3 0.92 9.6 0.3 2.1 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain FANCL_C PF11793.8 KXS15688.1 - 0.58 10.4 3.4 4 7.7 3.4 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3H2C3 PF17122.5 KXS15688.1 - 1.1 9.3 6.6 3.3 7.8 6.5 1.9 1 1 0 1 1 1 0 Zinc-finger RINGv PF12906.7 KXS15688.1 - 1.8 8.8 3.9 3.2 7.9 3.9 1.4 1 0 0 1 1 1 0 RING-variant domain Prok-RING_1 PF14446.6 KXS15688.1 - 1.9 8.5 6.0 8.3 6.4 0.4 2.5 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 SH3_9 PF14604.6 KXS15689.1 - 1.7e-06 27.8 0.0 7.7e-06 25.7 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 KXS15689.1 - 0.00083 18.9 0.0 0.0017 17.9 0.0 1.5 1 0 0 1 1 1 1 SH3 domain MFS_1 PF07690.16 KXS15691.1 - 1.9e-40 138.9 20.9 2.4e-40 138.5 20.9 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXS15691.1 - 3.5e-08 32.7 5.7 3.5e-08 32.7 5.7 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 KXS15691.1 - 8.1e-06 25.4 12.9 3.1e-05 23.4 11.3 2.2 1 1 1 2 2 2 2 Uncharacterised MFS-type transporter YbfB MFS_1_like PF12832.7 KXS15691.1 - 2.2e-05 23.5 19.9 0.0048 15.8 9.0 3.0 1 1 2 3 3 3 3 MFS_1 like family OATP PF03137.20 KXS15691.1 - 7.8e-05 21.2 6.5 0.0056 15.0 4.0 2.3 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family LacY_symp PF01306.19 KXS15691.1 - 0.0056 15.5 9.6 0.23 10.2 6.5 2.3 1 1 1 2 2 2 2 LacY proton/sugar symporter MFS_1 PF07690.16 KXS15692.1 - 2.9e-54 184.3 40.9 6.3e-39 133.9 13.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KXS15692.1 - 1e-13 50.9 18.9 2.8e-07 29.8 3.9 3.2 1 1 2 3 3 3 3 MFS_1 like family MFS_3 PF05977.13 KXS15692.1 - 1e-06 27.5 20.7 0.00012 20.7 9.1 2.1 2 0 0 2 2 2 2 Transmembrane secretion effector OATP PF03137.20 KXS15692.1 - 1.9e-06 26.5 6.4 1e-05 24.0 1.0 3.0 1 1 1 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family ATG22 PF11700.8 KXS15692.1 - 0.083 11.5 11.3 0.29 9.7 0.7 2.4 2 0 0 2 2 2 0 Vacuole effluxer Atg22 like DUF697 PF05128.12 KXS15692.1 - 0.39 10.4 2.7 0.84 9.3 2.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF697) Clr2_transil PF16761.5 KXS15693.1 - 1e-15 58.3 1.6 1.8e-14 54.3 1.6 2.4 1 1 0 1 1 1 1 Transcription-silencing protein, cryptic loci regulator Clr2 SH3_9 PF14604.6 KXS15694.1 - 1.7e-05 24.6 0.1 0.0085 15.9 0.0 3.2 3 0 0 3 3 3 2 Variant SH3 domain SH3_1 PF00018.28 KXS15694.1 - 0.0062 16.1 0.0 0.17 11.5 0.0 2.6 2 0 0 2 2 2 1 SH3 domain TOBE_2 PF08402.10 KXS15694.1 - 0.021 15.0 0.5 1.5 9.0 0.1 3.4 3 0 0 3 3 3 0 TOBE domain DUF3801 PF12687.7 KXS15694.1 - 0.52 10.4 3.4 1.2 9.2 1.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3801) DIOX_N PF14226.6 KXS15696.1 - 5e-22 78.9 0.0 9.2e-22 78.0 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KXS15696.1 - 4.9e-14 52.7 0.0 8.4e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Amidase PF01425.21 KXS15697.1 - 0.0011 18.1 0.0 0.0015 17.5 0.0 1.2 1 0 0 1 1 1 1 Amidase MtrF PF09472.10 KXS15697.1 - 0.052 13.0 0.0 0.12 11.8 0.0 1.6 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) PQ-loop PF04193.14 KXS15698.1 - 2.8e-17 62.2 5.7 2.7e-15 55.9 1.4 2.9 3 0 0 3 3 3 2 PQ loop repeat PgaD PF13994.6 KXS15698.1 - 8.4e-05 22.7 2.5 0.095 12.8 0.0 3.0 1 1 2 3 3 3 3 PgaD-like protein Ribosomal_L37ae PF01780.19 KXS15699.1 - 2.9e-26 91.3 4.3 3.2e-26 91.2 4.3 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family zf-RING_13 PF17977.1 KXS15699.1 - 0.0012 19.0 2.6 0.0014 18.8 2.6 1.1 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain A2L_zn_ribbon PF08792.10 KXS15699.1 - 0.024 14.3 2.3 3.6 7.4 0.3 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain Zn_Tnp_IS1595 PF12760.7 KXS15699.1 - 0.043 13.8 2.3 0.069 13.1 2.3 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Rsm1 PF08600.10 KXS15699.1 - 0.05 13.8 0.6 0.056 13.6 0.6 1.1 1 0 0 1 1 1 0 Rsm1-like zf-BED PF02892.15 KXS15699.1 - 0.074 13.1 4.8 2.8 8.0 0.4 2.1 1 1 1 2 2 2 0 BED zinc finger zf-C2H2 PF00096.26 KXS15699.1 - 0.22 12.0 2.9 8.8 7.0 0.5 2.3 2 0 0 2 2 2 0 Zinc finger, C2H2 type C1_2 PF03107.16 KXS15699.1 - 0.23 11.8 2.2 0.54 10.6 2.2 1.6 1 1 0 1 1 1 0 C1 domain DUF1451 PF07295.11 KXS15699.1 - 0.23 11.5 1.2 0.35 10.9 1.2 1.2 1 0 0 1 1 1 0 Zinc-ribbon containing domain zf-H2C2_2 PF13465.6 KXS15699.1 - 0.71 10.4 4.5 1.3 9.5 1.2 2.1 1 1 1 2 2 2 0 Zinc-finger double domain zf-Sec23_Sec24 PF04810.15 KXS15699.1 - 1.7 8.8 5.3 3.6 7.7 0.2 2.1 1 1 1 2 2 2 0 Sec23/Sec24 zinc finger Pec_lyase_C PF00544.19 KXS15700.1 - 7.3e-10 38.8 7.8 4.3e-08 33.0 7.8 2.2 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 KXS15700.1 - 7.8e-07 29.1 8.7 4.4e-06 26.6 8.4 2.1 1 1 0 1 1 1 1 Right handed beta helix region AMP-binding PF00501.28 KXS15702.1 - 5.6e-60 203.1 0.0 7e-60 202.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXS15702.1 - 0.003 18.5 0.1 0.0057 17.6 0.1 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PNTB PF02233.16 KXS15703.1 - 1.8e-170 567.9 25.5 1.8e-170 567.9 25.5 2.0 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.21 KXS15703.1 - 3.1e-63 212.9 2.7 3.1e-63 212.9 2.7 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 KXS15703.1 - 8e-37 126.6 0.4 4.2e-35 121.0 0.0 2.6 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain PNTB_4TM PF12769.7 KXS15703.1 - 3.8e-27 94.6 5.6 3.8e-27 94.6 5.6 4.4 3 1 0 3 3 3 1 4TM region of pyridine nucleotide transhydrogenase, mitoch 2-Hacid_dh_C PF02826.19 KXS15703.1 - 4.9e-05 22.8 0.4 0.068 12.5 0.1 3.2 3 0 0 3 3 3 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 KXS15703.1 - 0.019 14.2 0.1 0.045 13.0 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ADH_zinc_N PF00107.26 KXS15703.1 - 0.047 13.7 0.8 0.36 10.8 0.4 2.8 2 1 1 3 3 3 0 Zinc-binding dehydrogenase NAD_binding_8 PF13450.6 KXS15703.1 - 0.078 13.2 0.9 0.9 9.8 0.6 2.8 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain DUF924 PF06041.11 KXS15706.1 - 1.2e-44 152.6 0.1 1.4e-44 152.4 0.1 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF924) NAD_binding_10 PF13460.6 KXS15707.1 - 5.8e-37 127.4 0.1 6.6e-37 127.2 0.1 1.0 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KXS15707.1 - 1.2e-10 40.8 0.0 1.7e-10 40.4 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KXS15707.1 - 6.3e-06 25.8 0.0 9.7e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KXS15707.1 - 8.3e-05 22.3 0.1 0.00054 19.6 0.1 2.2 2 1 0 2 2 2 1 NmrA-like family Polysacc_synt_2 PF02719.15 KXS15707.1 - 0.0004 19.6 0.0 0.0006 19.0 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.25 KXS15707.1 - 0.0022 17.5 0.1 0.0058 16.1 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase GDP_Man_Dehyd PF16363.5 KXS15707.1 - 0.06 12.7 0.0 0.073 12.5 0.0 1.1 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase PIF1 PF05970.14 KXS15708.1 - 3.8e-48 164.5 0.1 7.4e-20 71.4 0.0 3.2 3 0 0 3 3 3 3 PIF1-like helicase AAA_30 PF13604.6 KXS15708.1 - 6.9e-16 58.5 0.0 1.4e-09 38.0 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 KXS15708.1 - 0.0003 21.1 0.0 0.0012 19.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KXS15708.1 - 0.0085 16.4 0.0 0.021 15.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 KXS15708.1 - 0.012 15.1 0.0 0.022 14.2 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_16 PF13191.6 KXS15708.1 - 0.015 15.7 0.0 0.032 14.6 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain TsaE PF02367.17 KXS15708.1 - 0.036 14.1 0.0 2.1 8.4 0.0 2.5 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 KXS15708.1 - 0.04 13.4 0.0 0.075 12.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_11 PF13086.6 KXS15708.1 - 0.057 13.2 0.9 0.93 9.2 0.0 2.6 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 KXS15708.1 - 0.06 13.7 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 RNA helicase TrwB_AAD_bind PF10412.9 KXS15708.1 - 0.079 11.9 0.0 0.12 11.3 0.0 1.1 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain ABC_tran PF00005.27 KXS15708.1 - 0.098 13.2 0.0 0.22 12.1 0.0 1.6 1 0 0 1 1 1 0 ABC transporter T2SSE PF00437.20 KXS15708.1 - 0.15 11.1 0.1 0.35 9.9 0.1 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF87 PF01935.17 KXS15708.1 - 0.16 12.0 0.0 0.38 10.8 0.0 1.6 1 0 0 1 1 1 0 Helicase HerA, central domain AAA PF00004.29 KXS15708.1 - 0.17 12.3 0.0 0.33 11.4 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) IU_nuc_hydro PF01156.19 KXS15709.1 - 1e-15 58.2 0.0 1.1e-15 58.0 0.0 1.3 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase DUF2205 PF10224.9 KXS15710.1 - 0.0031 17.5 1.2 0.014 15.4 0.1 2.0 1 1 1 2 2 2 1 Short coiled-coil protein Tmemb_cc2 PF10267.9 KXS15710.1 - 0.0032 16.7 0.6 0.87 8.7 0.1 2.0 1 1 1 2 2 2 2 Predicted transmembrane and coiled-coil 2 protein Baculo_PEP_C PF04513.12 KXS15710.1 - 0.0068 16.5 3.0 0.0082 16.2 3.0 1.2 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Apolipoprotein PF01442.18 KXS15710.1 - 0.037 13.9 0.3 0.047 13.6 0.3 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Nas2_N PF18265.1 KXS15710.1 - 0.14 12.1 1.9 1.4 8.9 1.9 2.3 1 1 0 1 1 1 0 Nas2 N_terminal domain DUF1640 PF07798.11 KXS15710.1 - 0.27 11.3 2.8 0.58 10.2 2.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) Nbl1_Borealin_N PF10444.9 KXS15710.1 - 0.27 10.9 5.0 0.71 9.5 2.0 2.3 1 1 1 2 2 2 0 Nbl1 / Borealin N terminal VWA PF00092.28 KXS15711.1 - 1.1e-25 91.0 0.0 1.8e-25 90.2 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 KXS15711.1 - 1.3e-19 70.7 0.0 2.2e-19 69.9 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KXS15711.1 - 7.4e-17 62.0 0.1 1.5e-16 60.9 0.1 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 KXS15711.1 - 9.4e-07 28.4 0.1 1.8e-06 27.5 0.1 1.4 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein zf-RING_2 PF13639.6 KXS15711.1 - 7.8e-05 22.9 1.5 0.00017 21.9 1.5 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KXS15711.1 - 0.00094 18.9 1.1 0.0027 17.4 1.1 1.8 1 0 0 1 1 1 1 RING-like zinc finger Copine PF07002.16 KXS15711.1 - 0.032 13.7 0.0 0.055 12.9 0.0 1.2 1 0 0 1 1 1 0 Copine zf-C3HC4_2 PF13923.6 KXS15711.1 - 0.034 14.0 3.7 0.093 12.6 3.7 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 KXS15711.1 - 0.043 13.6 2.4 0.088 12.6 2.4 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING-like PF08746.11 KXS15711.1 - 0.089 13.1 0.2 0.23 11.8 0.2 1.7 1 0 0 1 1 1 0 RING-like domain Zn_ribbon_17 PF17120.5 KXS15711.1 - 0.3 10.7 2.3 0.42 10.3 1.3 1.7 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-rbx1 PF12678.7 KXS15711.1 - 0.31 11.4 1.9 1.5 9.2 2.1 2.1 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4_5 PF17121.5 KXS15711.1 - 0.34 10.8 1.7 0.7 9.8 1.7 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXS15711.1 - 0.61 10.0 2.6 1.6 8.6 2.6 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXS15711.1 - 6.4 6.8 7.4 0.88 9.6 3.3 1.8 2 0 0 2 2 1 0 zinc-RING finger domain CsbD PF05532.12 KXS15713.1 - 0.00031 20.6 0.1 0.00047 20.0 0.1 1.3 1 0 0 1 1 1 1 CsbD-like DnaJ PF00226.31 KXS15714.1 - 1e-18 67.2 0.0 2e-18 66.2 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain TPR_2 PF07719.17 KXS15714.1 - 5.5e-06 26.1 12.2 0.00069 19.5 0.7 5.5 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 KXS15714.1 - 1.1e-05 25.0 0.2 0.28 11.1 0.1 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 KXS15714.1 - 0.045 13.8 1.1 14 6.0 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 KXS15714.1 - 0.096 12.9 0.2 32 5.1 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 KXS15714.1 - 0.15 12.4 9.6 3.6 7.9 0.6 3.5 2 2 2 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KXS15714.1 - 0.43 10.8 1.5 1.6 9.0 1.0 2.2 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TIG PF01833.24 KXS15717.1 - 9.7e-06 25.6 0.1 2.3e-05 24.4 0.1 1.7 1 1 0 1 1 1 1 IPT/TIG domain Ank_2 PF12796.7 KXS15717.1 - 4.1e-05 24.1 0.0 8.8e-05 23.0 0.0 1.6 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXS15717.1 - 0.0011 19.5 0.0 0.61 10.7 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXS15717.1 - 0.0026 18.1 0.0 0.048 14.2 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 KXS15717.1 - 0.0065 16.8 0.0 0.024 14.9 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) EzrA PF06160.12 KXS15717.1 - 0.021 13.1 0.1 0.029 12.6 0.1 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Leu_zip PF15294.6 KXS15717.1 - 0.038 13.5 0.1 0.047 13.2 0.1 1.1 1 0 0 1 1 1 0 Leucine zipper HALZ PF02183.18 KXS15717.1 - 0.19 11.9 0.6 0.27 11.5 0.6 1.2 1 0 0 1 1 1 0 Homeobox associated leucine zipper Ribosomal_L24e PF01246.20 KXS15718.1 - 7.8e-29 99.7 0.2 7.8e-29 99.7 0.2 2.0 2 0 0 2 2 2 1 Ribosomal protein L24e DDHD PF02862.17 KXS15718.1 - 0.54 10.4 4.4 0.61 10.2 4.4 1.1 1 0 0 1 1 1 0 DDHD domain Oxidored_q2 PF00420.24 KXS15720.1 - 0.09 12.4 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L ParBc PF02195.18 KXS15720.1 - 0.13 12.6 0.0 0.2 12.0 0.0 1.3 1 0 0 1 1 1 0 ParB-like nuclease domain MFS_1 PF07690.16 KXS15722.1 - 2.6e-32 112.1 38.3 1.9e-29 102.7 28.6 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Cytochrom_B558a PF05038.13 KXS15722.1 - 0.9 9.1 3.0 2.2 7.8 3.0 1.6 1 0 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit FixG_C PF11614.8 KXS15724.1 - 0.086 13.1 0.0 0.13 12.5 0.0 1.2 1 0 0 1 1 1 0 IG-like fold at C-terminal of FixG, putative oxidoreductase LysM PF01476.20 KXS15725.1 - 1.2e-19 70.0 0.0 5.2e-10 39.2 0.0 2.3 2 0 0 2 2 2 2 LysM domain F-box_4 PF15966.5 KXS15726.1 - 0.0068 16.3 0.5 0.012 15.5 0.5 1.3 1 0 0 1 1 1 1 F-box F-box PF00646.33 KXS15726.1 - 0.0075 16.1 1.7 0.014 15.2 1.7 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KXS15726.1 - 0.015 15.2 1.3 0.03 14.2 1.3 1.5 1 0 0 1 1 1 0 F-box-like Hemerythrin PF01814.23 KXS15728.1 - 1.5e-08 35.4 0.8 2.8e-08 34.5 0.1 1.8 2 0 0 2 2 2 1 Hemerythrin HHE cation binding domain PI_PP_C PF18365.1 KXS15728.1 - 0.017 15.1 0.5 0.17 11.9 0.0 2.3 2 1 0 2 2 2 0 Phosphoinositide phosphatase C-terminal domain CheB_methylest PF01339.17 KXS15728.1 - 0.059 13.1 1.4 0.099 12.4 1.4 1.4 1 1 0 1 1 1 0 CheB methylesterase Hemerythrin PF01814.23 KXS15729.1 - 3.4e-09 37.4 2.1 5.2e-09 36.8 2.1 1.4 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Pep3_Vps18 PF05131.14 KXS15730.1 - 4.9e-18 65.4 0.0 7.5e-18 64.8 0.0 1.3 1 0 0 1 1 1 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 KXS15730.1 - 1.4e-08 34.8 0.0 4.5e-05 23.3 0.0 2.9 3 0 0 3 3 3 2 Region in Clathrin and VPS Vps39_2 PF10367.9 KXS15730.1 - 6.6e-06 26.5 0.0 1.4e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 zf-C3HC4_2 PF13923.6 KXS15730.1 - 5.4e-05 23.0 1.0 0.00011 21.9 1.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXS15730.1 - 0.0012 18.7 0.5 0.0027 17.6 0.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KXS15730.1 - 0.0015 18.5 0.6 0.0037 17.3 0.6 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 KXS15730.1 - 0.0048 17.2 0.9 0.0048 17.2 0.9 1.7 2 0 0 2 2 1 1 Ring finger domain DUF2175 PF09943.9 KXS15730.1 - 0.0069 16.7 0.1 0.024 14.9 0.1 1.9 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2175) Zn_ribbon_17 PF17120.5 KXS15730.1 - 0.0076 15.9 0.1 0.016 14.8 0.1 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type FTHFS PF01268.19 KXS15730.1 - 0.017 13.4 0.0 0.026 12.7 0.0 1.1 1 0 0 1 1 1 0 Formate--tetrahydrofolate ligase zf-C3HC4 PF00097.25 KXS15730.1 - 0.093 12.6 0.5 0.22 11.4 0.5 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KXS15730.1 - 0.13 12.5 0.3 0.3 11.4 0.3 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_11 PF17123.5 KXS15730.1 - 1.9 8.3 10.5 0.025 14.3 3.2 1.7 2 0 0 2 2 1 0 RING-like zinc finger F-box-like PF12937.7 KXS15735.1 - 1.5e-06 28.0 0.0 2.4e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 F-box-like Aminotran_5 PF00266.19 KXS15736.1 - 1.1e-91 307.5 0.0 1.3e-91 307.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KXS15736.1 - 2.9e-06 26.8 0.1 4e-06 26.3 0.1 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 KXS15736.1 - 8e-06 25.4 0.0 2.5e-05 23.8 0.1 1.7 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.19 KXS15736.1 - 0.00084 18.2 0.0 0.0013 17.5 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Bax1-I PF01027.20 KXS15738.1 - 2.9e-44 151.4 31.1 3.4e-44 151.2 31.1 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 PGG PF13962.6 KXS15738.1 - 1.4 8.8 12.2 0.05 13.4 4.5 2.3 1 1 1 2 2 2 0 Domain of unknown function zf-Di19 PF05605.12 KXS15739.1 - 0.075 13.3 0.1 0.15 12.4 0.1 1.5 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Ank PF00023.30 KXS15740.1 - 2.1e-09 37.4 0.0 0.0026 18.1 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 KXS15740.1 - 1.8e-08 34.8 0.0 1.1e-07 32.3 0.0 1.9 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXS15740.1 - 1.4e-07 31.9 0.1 0.0022 18.5 0.0 3.1 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXS15740.1 - 1e-06 28.9 0.7 0.0082 16.4 0.2 3.3 2 2 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXS15740.1 - 4.5e-06 26.6 0.0 0.058 14.0 0.0 3.0 3 1 0 3 3 3 2 Ankyrin repeat Reductase_C PF14759.6 KXS15740.1 - 0.2 12.3 0.7 7.2 7.2 0.0 2.1 1 1 1 2 2 2 0 Reductase C-terminal BssS PF13991.6 KXS15742.1 - 0.059 13.4 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 BssS protein family VIR_N PF15912.5 KXS15742.1 - 0.11 12.1 0.8 4.7 6.7 0.0 2.1 2 0 0 2 2 2 0 Virilizer, N-terminal Hemerythrin PF01814.23 KXS15744.1 - 1.9e-06 28.5 1.6 0.041 14.5 0.0 2.7 2 1 0 2 2 2 2 Hemerythrin HHE cation binding domain zf-MYND PF01753.18 KXS15745.1 - 1.8e-07 31.2 4.8 2.7e-07 30.6 4.8 1.3 1 0 0 1 1 1 1 MYND finger GATase PF00117.28 KXS15747.1 - 6.9e-09 35.7 0.0 1e-08 35.2 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Cys_Met_Meta_PP PF01053.20 KXS15748.1 - 2.2e-108 362.2 0.0 2.6e-108 362.0 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 KXS15748.1 - 8.4e-08 31.9 0.0 1.3e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 KXS15748.1 - 9.9e-08 31.5 0.0 1.7e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KXS15748.1 - 1.5e-06 27.4 0.0 2.4e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KXS15748.1 - 2.1e-05 23.9 0.0 6.3e-05 22.4 0.0 1.7 1 1 0 1 1 1 1 Beta-eliminating lyase GDC-P PF02347.16 KXS15748.1 - 0.021 13.7 0.0 0.031 13.1 0.0 1.2 1 0 0 1 1 1 0 Glycine cleavage system P-protein BTRD1 PF17660.1 KXS15748.1 - 0.15 11.9 0.0 0.34 10.7 0.0 1.6 1 0 0 1 1 1 0 Bacterial tandem repeat domain 1 Ephrin_rec_like PF07699.13 KXS15749.1 - 3e-31 106.9 79.8 3.6e-10 39.4 6.7 8.8 1 1 8 9 9 9 8 Putative ephrin-receptor like NCD3G PF07562.14 KXS15749.1 - 9.7e-15 54.3 46.0 0.0015 18.4 0.4 7.2 3 1 6 10 10 10 9 Nine Cysteines Domain of family 3 GPCR TNFR_c6 PF00020.18 KXS15749.1 - 2.8e-08 34.0 50.8 0.099 13.1 0.7 9.0 4 2 6 10 10 10 9 TNFR/NGFR cysteine-rich region DDE_Tnp_4 PF13359.6 KXS15751.1 - 0.00021 21.0 0.3 0.00035 20.3 0.3 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 KXS15751.1 - 0.012 15.3 0.1 0.016 14.8 0.1 1.1 1 0 0 1 1 1 0 Plant transposon protein Myb_DNA-bind_3 PF12776.7 KXS15752.1 - 4.1e-11 43.7 1.3 7.3e-11 42.9 0.8 1.6 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Peroxin-13_N PF04088.13 KXS15752.1 - 0.012 15.9 0.0 0.012 15.9 0.0 1.1 1 0 0 1 1 1 0 Peroxin 13, N-terminal region Hemerythrin PF01814.23 KXS15753.1 - 7.6e-08 33.0 12.8 1.1e-07 32.5 12.8 1.4 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Nipped-B_C PF12830.7 KXS15753.1 - 0.03 14.2 0.4 0.043 13.8 0.4 1.3 1 0 0 1 1 1 0 Sister chromatid cohesion C-terminus F-box-like PF12937.7 KXS15754.1 - 1.7e-08 34.2 0.1 4.2e-08 33.0 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXS15754.1 - 0.0055 16.5 0.0 0.015 15.2 0.0 1.7 1 0 0 1 1 1 1 F-box domain Sdh_cyt PF01127.22 KXS15755.1 - 0.00017 21.6 8.3 0.009 16.0 3.2 2.4 2 0 0 2 2 2 2 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF1691 PF07950.11 KXS15755.1 - 0.0025 18.5 1.7 0.0031 18.2 0.2 2.0 3 0 0 3 3 3 1 Protein of unknown function (DUF1691) Ferric_reduct PF01794.19 KXS15755.1 - 0.022 14.9 6.2 0.97 9.6 2.5 2.8 2 1 0 2 2 2 0 Ferric reductase like transmembrane component DUF4405 PF14358.6 KXS15755.1 - 0.027 15.0 1.0 5.7 7.6 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4405) DUF1948 PF09185.10 KXS15756.1 - 0.053 13.4 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1948) ubiquitin PF00240.23 KXS15756.1 - 0.15 11.8 0.2 1.4 8.7 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin family zf-RING_2 PF13639.6 KXS15757.1 - 3.3e-11 43.3 3.6 6.2e-11 42.5 3.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KXS15757.1 - 6.4e-10 38.6 0.2 1.3e-09 37.6 0.2 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 KXS15757.1 - 1.8e-06 27.7 0.5 3.7e-06 26.7 0.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KXS15757.1 - 1.9e-06 28.1 5.5 3e-06 27.4 5.5 1.5 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KXS15757.1 - 3.3e-06 26.8 3.1 6.9e-06 25.8 3.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXS15757.1 - 1.6e-05 24.7 0.2 3.1e-05 23.8 0.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 KXS15757.1 - 2.2e-05 24.4 0.8 2.7e-05 24.1 0.8 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 KXS15757.1 - 0.0023 17.8 0.8 0.0036 17.1 0.8 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KXS15757.1 - 0.0035 17.3 4.2 0.0035 17.3 2.0 1.9 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KXS15757.1 - 0.02 14.8 0.6 0.042 13.7 0.6 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 KXS15757.1 - 0.036 14.2 2.6 0.28 11.4 2.0 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 KXS15757.1 - 0.11 12.1 3.5 0.26 10.9 3.4 1.7 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3H2C3 PF17122.5 KXS15757.1 - 0.12 12.5 3.3 0.43 10.7 3.3 1.9 1 1 0 1 1 1 0 Zinc-finger zf-C3HC4_4 PF15227.6 KXS15757.1 - 0.12 12.5 2.3 0.29 11.3 2.3 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING PHD PF00628.29 KXS15757.1 - 3.7 7.5 6.3 9.9 6.1 4.1 2.3 1 1 1 2 2 2 0 PHD-finger Sdh_cyt PF01127.22 KXS15758.1 - 1e-06 28.8 4.9 2.4e-05 24.3 0.9 2.3 2 0 0 2 2 2 2 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF1691 PF07950.11 KXS15758.1 - 0.00013 22.7 2.0 0.0072 17.0 0.1 2.6 2 1 0 2 2 2 2 Protein of unknown function (DUF1691) Ferric_reduct PF01794.19 KXS15758.1 - 0.0076 16.4 1.6 0.13 12.4 0.2 2.5 2 1 0 2 2 2 1 Ferric reductase like transmembrane component DUF3611 PF12263.8 KXS15758.1 - 0.15 12.0 0.1 0.15 12.0 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3611) DUF3237 PF11578.8 KXS15759.1 - 1.7e-26 92.9 0.0 1.9e-26 92.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) DUF3827 PF12877.7 KXS15760.1 - 0.16 10.3 0.0 0.21 10.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) GDP_Man_Dehyd PF16363.5 KXS15761.1 - 1.5e-50 172.5 0.0 1.8e-50 172.2 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KXS15761.1 - 6e-46 156.9 0.0 8.4e-46 156.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXS15761.1 - 5.1e-15 55.2 0.0 1.3e-14 53.8 0.0 1.6 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KXS15761.1 - 9.2e-13 47.9 0.0 1.4e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KXS15761.1 - 1.1e-11 44.5 0.0 7.7e-11 41.7 0.0 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 KXS15761.1 - 4.5e-07 29.9 0.0 7.2e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.12 KXS15761.1 - 1.2e-05 24.7 0.1 0.00033 19.9 0.1 2.3 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.25 KXS15761.1 - 6.4e-05 22.5 0.0 0.00011 21.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.6 KXS15761.1 - 0.00032 20.6 0.0 0.0011 18.9 0.0 1.8 2 0 0 2 2 2 1 NAD(P)H-binding adh_short_C2 PF13561.6 KXS15761.1 - 0.084 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase UDPG_MGDP_dh_N PF03721.14 KXS15761.1 - 0.094 12.3 0.1 0.38 10.3 0.1 1.9 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain GATase_4 PF13230.6 KXS15761.1 - 0.16 10.8 0.0 0.26 10.2 0.0 1.3 1 0 0 1 1 1 0 Glutamine amidotransferases class-II KASH_CCD PF14662.6 KXS15762.1 - 2.1e-06 27.7 8.6 3.8e-06 26.9 8.6 1.3 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH Ank_3 PF13606.6 KXS15762.1 - 1.8e-05 24.8 0.1 0.041 14.4 0.0 3.7 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.7 KXS15762.1 - 3.1e-05 24.5 0.0 0.19 12.3 0.0 3.2 3 0 0 3 3 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXS15762.1 - 0.00011 22.5 0.1 0.24 11.8 0.0 3.0 3 0 0 3 3 2 1 Ankyrin repeats (many copies) Rootletin PF15035.6 KXS15762.1 - 0.00043 20.3 12.2 0.00076 19.6 12.2 1.3 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion FPP PF05911.11 KXS15762.1 - 0.00046 18.5 5.6 0.00089 17.6 5.6 1.4 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil Ank_4 PF13637.6 KXS15762.1 - 0.0011 19.5 0.0 5.7 7.6 0.0 3.6 3 0 0 3 3 3 0 Ankyrin repeats (many copies) SH3_9 PF14604.6 KXS15762.1 - 0.0018 18.1 0.8 0.0091 15.8 0.0 2.5 3 0 0 3 3 2 1 Variant SH3 domain HALZ PF02183.18 KXS15762.1 - 0.0028 17.8 1.6 0.066 13.4 0.3 2.6 1 1 1 2 2 2 1 Homeobox associated leucine zipper DUF4763 PF15960.5 KXS15762.1 - 0.0029 17.0 2.0 0.0046 16.3 2.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4763) Ank PF00023.30 KXS15762.1 - 0.005 17.2 0.0 2.2 8.9 0.0 3.6 3 0 0 3 3 3 1 Ankyrin repeat GOLGA2L5 PF15070.6 KXS15762.1 - 0.0091 14.7 5.1 0.012 14.3 5.1 1.1 1 0 0 1 1 1 1 Putative golgin subfamily A member 2-like protein 5 FAM76 PF16046.5 KXS15762.1 - 0.011 15.1 3.5 0.016 14.5 3.5 1.2 1 0 0 1 1 1 0 FAM76 protein JIP_LZII PF16471.5 KXS15762.1 - 0.011 15.9 2.9 0.011 15.9 2.9 2.3 3 0 0 3 3 1 0 JNK-interacting protein leucine zipper II Spc7 PF08317.11 KXS15762.1 - 0.012 14.5 9.8 0.021 13.7 9.8 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF812 PF05667.11 KXS15762.1 - 0.017 14.0 6.4 0.025 13.5 6.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Cluap1 PF10234.9 KXS15762.1 - 0.024 14.1 7.0 0.037 13.4 7.0 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 THOC7 PF05615.13 KXS15762.1 - 0.027 14.8 12.5 0.053 13.8 12.5 1.4 1 0 0 1 1 1 0 Tho complex subunit 7 TSC22 PF01166.18 KXS15762.1 - 0.03 14.6 2.0 2.9 8.3 0.5 3.5 1 1 2 3 3 3 0 TSC-22/dip/bun family TMCO5 PF14992.6 KXS15762.1 - 0.047 13.3 5.0 0.078 12.5 5.0 1.3 1 0 0 1 1 1 0 TMCO5 family BRE1 PF08647.11 KXS15762.1 - 0.071 13.2 12.6 0.12 12.4 12.6 1.4 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase DUF724 PF05266.14 KXS15762.1 - 0.074 12.9 8.0 0.15 11.9 8.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF724) GAS PF13851.6 KXS15762.1 - 0.086 12.2 7.8 0.17 11.2 7.8 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding SH3_1 PF00018.28 KXS15762.1 - 0.097 12.3 0.0 0.31 10.7 0.0 1.9 2 0 0 2 2 1 0 SH3 domain YabA PF06156.13 KXS15762.1 - 0.13 12.9 6.0 0.26 12.0 3.3 2.5 1 1 1 2 2 2 0 Initiation control protein YabA bZIP_2 PF07716.15 KXS15762.1 - 0.16 12.1 12.7 0.21 11.7 2.1 3.5 2 1 1 3 3 3 0 Basic region leucine zipper Jnk-SapK_ap_N PF09744.9 KXS15762.1 - 0.19 11.9 11.5 0.39 10.9 11.5 1.5 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 CENP-F_leu_zip PF10473.9 KXS15762.1 - 0.2 11.7 10.0 0.48 10.5 10.0 1.6 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Presenilin PF01080.17 KXS15762.1 - 0.21 10.3 0.9 0.35 9.6 0.9 1.3 1 0 0 1 1 1 0 Presenilin Fez1 PF06818.15 KXS15762.1 - 0.27 11.7 12.7 0.79 10.1 11.5 1.9 1 1 1 2 2 2 0 Fez1 ADIP PF11559.8 KXS15762.1 - 0.28 11.3 15.6 0.44 10.6 13.9 1.9 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding ATG16 PF08614.11 KXS15762.1 - 0.29 11.3 26.5 0.05 13.8 21.3 2.1 2 1 0 2 2 1 0 Autophagy protein 16 (ATG16) MAD PF05557.13 KXS15762.1 - 0.31 9.3 12.6 0.47 8.8 12.6 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein APG6_N PF17675.1 KXS15762.1 - 0.34 11.4 15.9 0.95 10.0 16.0 1.6 1 1 0 1 1 1 0 Apg6 coiled-coil region HAUS-augmin3 PF14932.6 KXS15762.1 - 0.41 10.2 11.8 0.21 11.1 9.8 1.5 2 0 0 2 2 1 0 HAUS augmin-like complex subunit 3 bZIP_1 PF00170.21 KXS15762.1 - 0.41 10.8 0.1 0.16 12.1 1.1 2.8 2 1 1 3 3 2 0 bZIP transcription factor Mucin15 PF15672.5 KXS15762.1 - 0.46 9.9 10.9 3 7.2 4.3 2.5 2 1 0 2 2 2 0 Cell-membrane associated Mucin15 UPF0242 PF06785.11 KXS15762.1 - 0.55 10.3 6.0 0.95 9.5 6.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Csm1_N PF18504.1 KXS15762.1 - 0.56 10.6 11.7 1.7 9.0 2.4 3.4 1 1 2 3 3 3 0 Csm1 N-terminal domain Atg14 PF10186.9 KXS15762.1 - 0.57 9.2 10.2 1 8.4 10.2 1.4 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Macoilin PF09726.9 KXS15762.1 - 0.64 8.5 9.7 1 7.8 9.7 1.2 1 0 0 1 1 1 0 Macoilin family DUF3584 PF12128.8 KXS15762.1 - 0.73 7.3 13.3 1 6.8 13.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DivIC PF04977.15 KXS15762.1 - 0.78 9.6 15.8 1.8 8.4 3.2 3.3 1 1 2 3 3 3 0 Septum formation initiator TMF_TATA_bd PF12325.8 KXS15762.1 - 0.9 9.8 13.1 7 6.9 2.4 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF3450 PF11932.8 KXS15762.1 - 0.91 8.8 15.4 0.099 11.9 6.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF4472 PF14739.6 KXS15762.1 - 0.98 10.2 8.0 5.2 7.9 8.5 1.9 2 0 0 2 2 1 0 Domain of unknown function (DUF4472) Cep57_CLD_2 PF14197.6 KXS15762.1 - 1.1 9.4 10.2 1.3 9.1 5.2 2.8 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 Nup54 PF13874.6 KXS15762.1 - 1.2 9.3 14.1 0.39 10.8 11.1 1.8 2 0 0 2 2 1 0 Nucleoporin complex subunit 54 OmpH PF03938.14 KXS15762.1 - 1.2 9.5 7.3 2.1 8.7 7.3 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) AAA_13 PF13166.6 KXS15762.1 - 1.4 7.5 10.8 0.84 8.2 1.0 2.1 1 1 1 2 2 2 0 AAA domain ZapB PF06005.12 KXS15762.1 - 1.4 9.4 14.5 0.12 12.8 3.3 2.9 1 1 1 2 2 2 0 Cell division protein ZapB V_ATPase_I PF01496.19 KXS15762.1 - 1.6 6.5 5.2 2.2 6.1 5.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMF_DNA_bd PF12329.8 KXS15762.1 - 1.7 8.7 15.4 2.8 8.0 3.8 2.7 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding LMBR1 PF04791.16 KXS15762.1 - 2.2 7.1 3.3 3 6.6 3.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Mod_r PF07200.13 KXS15762.1 - 2.8 8.0 10.9 1.7 8.8 6.3 2.3 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein SlyX PF04102.12 KXS15762.1 - 3.1 8.5 14.0 0.26 11.9 3.3 3.3 2 1 1 3 3 3 0 SlyX DUF4200 PF13863.6 KXS15762.1 - 3.8 7.9 12.5 2.3 8.6 8.0 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) DUF641 PF04859.12 KXS15762.1 - 3.9 7.8 10.6 1.1 9.6 2.6 2.4 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Mt_ATP-synt_B PF05405.14 KXS15762.1 - 4 7.0 8.6 7.7 6.1 8.6 1.4 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Uso1_p115_C PF04871.13 KXS15762.1 - 4.6 7.6 18.3 0.83 10.0 11.6 2.7 2 1 1 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region GBP_C PF02841.14 KXS15762.1 - 4.7 6.5 12.4 7.2 5.9 12.4 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Swi5 PF07061.11 KXS15762.1 - 5.8 7.1 9.5 5.7 7.1 0.9 2.6 1 1 2 3 3 3 0 Swi5 Muted PF14942.6 KXS15762.1 - 7.7 6.8 10.7 3.5 8.0 7.3 2.1 3 0 0 3 3 1 0 Organelle biogenesis, Muted-like protein SH3_1 PF00018.28 KXS15763.1 - 4e-06 26.3 0.0 7.1e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KXS15763.1 - 2.1e-05 24.3 0.0 4.1e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Shugoshin_N PF07558.11 KXS15763.1 - 0.001 18.9 1.2 0.011 15.6 0.1 2.3 1 1 1 2 2 2 1 Shugoshin N-terminal coiled-coil region Rootletin PF15035.6 KXS15763.1 - 0.0012 19.0 5.4 0.0024 17.9 5.4 1.5 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion YabA PF06156.13 KXS15763.1 - 0.002 18.7 2.7 0.0021 18.7 1.4 1.6 1 1 1 2 2 2 1 Initiation control protein YabA Cluap1 PF10234.9 KXS15763.1 - 0.013 14.9 7.5 0.019 14.4 7.5 1.1 1 0 0 1 1 1 0 Clusterin-associated protein-1 Ank_3 PF13606.6 KXS15763.1 - 0.026 15.0 0.0 0.55 11.0 0.0 2.8 3 0 0 3 3 2 0 Ankyrin repeat ADIP PF11559.8 KXS15763.1 - 0.031 14.4 14.4 0.15 12.1 7.2 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding HMMR_C PF15908.5 KXS15763.1 - 0.036 14.3 0.8 0.92 9.8 0.5 2.3 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor C-terminal ATG16 PF08614.11 KXS15763.1 - 0.05 13.8 13.0 0.086 13.1 13.0 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) PI3K_P85_iSH2 PF16454.5 KXS15763.1 - 0.064 12.9 1.5 0.12 12.0 1.5 1.4 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain APG6_N PF17675.1 KXS15763.1 - 0.17 12.4 3.7 0.32 11.5 3.7 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF2968 PF11180.8 KXS15763.1 - 0.22 11.2 8.7 0.37 10.4 8.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) DivIC PF04977.15 KXS15763.1 - 0.23 11.2 7.7 0.6 9.9 2.2 2.4 2 0 0 2 2 2 0 Septum formation initiator DUF3450 PF11932.8 KXS15763.1 - 0.26 10.6 7.3 0.44 9.8 7.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) UPF0242 PF06785.11 KXS15763.1 - 0.61 10.2 3.1 0.97 9.5 3.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Cnn_1N PF07989.11 KXS15763.1 - 0.63 10.2 3.0 1.8 8.8 1.2 2.2 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 ZapB PF06005.12 KXS15763.1 - 0.93 10.0 5.3 0.51 10.8 2.7 1.8 1 1 1 2 2 2 0 Cell division protein ZapB FAM76 PF16046.5 KXS15763.1 - 0.97 8.7 4.5 1.7 7.9 4.5 1.3 1 0 0 1 1 1 0 FAM76 protein CENP-H PF05837.12 KXS15763.1 - 1.4 9.3 13.7 0.22 12.0 4.6 2.4 1 1 1 2 2 2 0 Centromere protein H (CENP-H) KASH_CCD PF14662.6 KXS15764.1 - 0.00017 21.4 0.3 0.00021 21.2 0.3 1.1 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH TolA_bind_tri PF16331.5 KXS15764.1 - 0.00042 20.3 1.6 0.0055 16.8 1.6 2.0 1 1 0 1 1 1 1 TolA binding protein trimerisation DUF4618 PF15397.6 KXS15764.1 - 0.0011 18.5 0.1 0.0012 18.4 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4618) TSC22 PF01166.18 KXS15764.1 - 0.0015 18.8 0.6 0.028 14.7 0.1 2.2 1 1 1 2 2 2 1 TSC-22/dip/bun family Prefoldin_2 PF01920.20 KXS15764.1 - 0.015 15.3 0.1 0.02 14.8 0.1 1.2 1 0 0 1 1 1 0 Prefoldin subunit DUF3772 PF12607.8 KXS15764.1 - 0.02 14.7 0.4 0.035 13.9 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3772) HAP1_N PF04849.13 KXS15764.1 - 0.03 13.5 0.2 0.036 13.3 0.2 1.1 1 0 0 1 1 1 0 HAP1 N-terminal conserved region HALZ PF02183.18 KXS15764.1 - 0.056 13.7 0.4 0.64 10.3 0.1 2.0 1 1 1 2 2 2 0 Homeobox associated leucine zipper bZIP_1 PF00170.21 KXS15764.1 - 0.066 13.3 0.2 0.093 12.8 0.2 1.3 1 0 0 1 1 1 0 bZIP transcription factor Tropomyosin_1 PF12718.7 KXS15764.1 - 0.066 13.4 0.1 0.08 13.1 0.1 1.1 1 0 0 1 1 1 0 Tropomyosin like CLZ PF16526.5 KXS15764.1 - 0.067 13.6 0.2 0.093 13.1 0.2 1.2 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Rootletin PF15035.6 KXS15764.1 - 0.092 12.8 0.3 0.11 12.5 0.3 1.1 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion T6PP_N PF18572.1 KXS15764.1 - 0.12 12.2 0.9 1.1 9.1 0.8 1.9 1 1 1 2 2 2 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain Csm1_N PF18504.1 KXS15764.1 - 0.13 12.7 0.2 0.19 12.1 0.2 1.2 1 0 0 1 1 1 0 Csm1 N-terminal domain Vps51 PF08700.11 KXS15764.1 - 0.16 12.1 1.7 3.1 8.0 0.4 2.1 1 1 1 2 2 2 0 Vps51/Vps67 CBM_21 PF03370.13 KXS15766.1 - 1.4e-19 70.4 0.0 7e-19 68.1 0.0 1.8 1 1 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 KXS15766.1 - 2.9e-08 34.2 0.0 0.00031 21.3 0.0 2.2 2 0 0 2 2 2 2 Starch/carbohydrate-binding module (family 53) CAMSAP_CH PF11971.8 KXS15766.1 - 0.043 13.6 0.0 0.08 12.8 0.0 1.4 1 0 0 1 1 1 0 CAMSAP CH domain Thiolase_N PF00108.23 KXS15767.1 - 1.2e-17 64.2 0.0 1.2e-13 51.0 0.0 2.3 2 0 0 2 2 2 2 Thiolase, N-terminal domain Thiolase_C PF02803.18 KXS15767.1 - 1.2e-10 41.1 0.1 8.1e-10 38.4 0.0 2.4 3 0 0 3 3 3 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KXS15767.1 - 0.0024 17.5 0.1 0.07 12.7 0.0 2.3 1 1 1 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KXS15767.1 - 0.0087 15.9 0.2 0.21 11.5 0.0 2.8 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Ketoacyl-synt_C PF02801.22 KXS15767.1 - 0.04 13.9 0.4 2 8.5 0.0 2.9 3 1 0 3 3 3 0 Beta-ketoacyl synthase, C-terminal domain adh_short_C2 PF13561.6 KXS15768.1 - 9.9e-52 175.8 0.1 1.1e-51 175.6 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXS15768.1 - 5.7e-42 143.4 0.0 7.5e-42 143.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXS15768.1 - 6.9e-06 26.1 0.2 2.1e-05 24.5 0.2 1.9 1 1 0 1 1 1 1 KR domain CoA_binding_2 PF13380.6 KXS15768.1 - 0.015 15.8 0.0 0.046 14.2 0.0 1.8 1 0 0 1 1 1 0 CoA binding domain TIR_2 PF13676.6 KXS15768.1 - 0.15 12.7 0.1 2 9.1 0.0 2.3 2 0 0 2 2 2 0 TIR domain DUF58 PF01882.18 KXS15768.1 - 0.17 12.2 0.2 8.9 6.7 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function DUF58 Pkinase PF00069.25 KXS15769.1 - 3.4e-76 256.1 0.0 3.9e-76 255.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS15769.1 - 3.8e-30 105.1 0.0 4.8e-30 104.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXS15769.1 - 2.4e-05 23.8 0.0 0.00028 20.3 0.0 2.2 1 1 1 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 KXS15769.1 - 3.6e-05 22.9 0.1 8.5e-05 21.7 0.1 1.5 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KXS15769.1 - 6.5e-05 23.0 0.1 0.00086 19.3 0.1 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KXS15769.1 - 0.0017 17.7 0.1 0.0028 17.0 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 KXS15769.1 - 0.0079 15.3 0.0 0.014 14.5 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 FTA2 PF13095.6 KXS15769.1 - 0.032 13.9 0.4 0.96 9.0 0.1 2.2 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 KXS15769.1 - 0.036 13.7 0.0 0.053 13.1 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 KXS15769.1 - 0.046 12.5 0.1 0.097 11.4 0.0 1.5 2 0 0 2 2 2 0 Fungal protein kinase Bax1-I PF01027.20 KXS15770.1 - 3.1e-45 154.6 29.8 3.6e-45 154.3 29.8 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 HMG_box PF00505.19 KXS15771.1 - 1.2e-15 57.7 1.1 2.4e-15 56.7 1.1 1.5 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KXS15771.1 - 3e-06 27.7 0.2 6.4e-06 26.7 0.2 1.5 1 0 0 1 1 1 1 HMG-box domain HMG_box PF00505.19 KXS15772.1 - 1.4e-15 57.4 3.0 2.2e-15 56.8 3.0 1.3 1 1 0 1 1 1 1 HMG (high mobility group) box UxaE PF16257.5 KXS15772.1 - 0.023 13.4 0.1 0.025 13.2 0.1 1.0 1 0 0 1 1 1 0 tagaturonate epimerase SOG2 PF10428.9 KXS15773.1 - 2 7.5 13.4 2.2 7.4 13.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Pkinase PF00069.25 KXS15774.1 - 2.4e-48 164.8 0.0 2.8e-48 164.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS15774.1 - 3.3e-28 98.7 0.0 4.2e-28 98.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase zf-MYND PF01753.18 KXS15778.1 - 1.3e-10 41.1 8.3 1.3e-10 41.1 8.3 2.3 2 1 0 2 2 2 1 MYND finger zf-C6H2 PF15801.5 KXS15778.1 - 0.0007 19.8 5.3 0.0007 19.8 5.3 2.1 1 1 1 2 2 2 1 zf-MYND-like zinc finger, mRNA-binding 4HBT_3 PF13622.6 KXS15779.1 - 7.1e-28 98.5 0.2 1.1e-27 97.9 0.2 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 KXS15779.1 - 0.091 13.1 0.0 2.6 8.5 0.0 2.5 2 0 0 2 2 2 0 Thioesterase superfamily Asp PF00026.23 KXS15780.1 - 6.7e-17 61.9 0.1 3.6e-13 49.6 0.0 2.1 2 0 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 KXS15780.1 - 3.2e-07 30.8 0.0 5.9e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal 4HBT_3 PF13622.6 KXS15781.1 - 2.6e-32 113.1 0.1 3.9e-32 112.5 0.1 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 KXS15781.1 - 0.01 16.2 0.0 0.14 12.5 0.0 2.6 3 0 0 3 3 3 0 Thioesterase superfamily Asparaginase PF00710.20 KXS15782.1 - 1.9e-57 193.9 0.0 7.7e-57 191.9 0.0 2.0 1 1 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 KXS15782.1 - 3.8e-25 88.3 0.3 1e-24 86.9 0.3 1.7 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain Ank_5 PF13857.6 KXS15782.1 - 8.2e-18 64.3 0.2 1.6e-08 34.6 0.0 3.6 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXS15782.1 - 2.1e-16 60.3 0.0 1.3e-06 28.9 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXS15782.1 - 1e-11 45.1 0.0 9.9e-06 26.0 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KXS15782.1 - 2e-11 43.8 0.0 0.00022 21.5 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 KXS15782.1 - 2.5e-09 36.6 0.0 0.0042 17.5 0.0 4.6 4 0 0 4 4 4 2 Ankyrin repeat ILVD_EDD PF00920.21 KXS15784.1 - 7.2e-12 44.7 0.0 9.5e-12 44.3 0.0 1.1 1 0 0 1 1 1 1 Dehydratase family Methyltransf_11 PF08241.12 KXS15785.1 - 3.4e-13 50.1 0.0 5.8e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXS15785.1 - 7.7e-13 49.0 0.0 1.3e-12 48.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXS15785.1 - 1e-10 41.7 0.0 1.7e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXS15785.1 - 4.6e-09 36.2 0.0 9.3e-09 35.2 0.0 1.5 1 1 1 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXS15785.1 - 5e-09 35.8 0.0 1.4e-08 34.4 0.0 1.6 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KXS15785.1 - 5.9e-09 36.6 0.0 1e-08 35.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Tir_receptor_C PF07489.11 KXS15785.1 - 0.074 13.0 0.1 0.12 12.4 0.1 1.2 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus Rsm22 PF09243.10 KXS15785.1 - 0.13 11.5 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 adh_short_C2 PF13561.6 KXS15787.1 - 2e-08 34.1 0.0 5.7e-05 22.8 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase zf-U1 PF06220.12 KXS15788.1 - 4.4e-09 36.0 0.2 7.8e-09 35.2 0.2 1.4 1 0 0 1 1 1 1 U1 zinc finger ARHGEF5_35 PF15441.6 KXS15788.1 - 0.013 14.5 3.8 0.03 13.3 2.5 2.0 2 0 0 2 2 2 0 Rho guanine nucleotide exchange factor 5/35 tRNA-synt_1 PF00133.22 KXS15788.1 - 0.025 12.8 1.1 0.032 12.5 1.1 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (I, L, M and V) zf-C2H2_jaz PF12171.8 KXS15788.1 - 0.072 13.4 3.2 0.24 11.7 3.2 1.9 1 1 0 1 1 1 0 Zinc-finger double-stranded RNA-binding OrsD PF12013.8 KXS15788.1 - 0.32 11.5 2.2 0.29 11.6 0.7 1.7 1 1 1 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D Brix PF04427.18 KXS15789.1 - 2.4e-46 158.3 0.0 3.2e-46 157.9 0.0 1.2 1 0 0 1 1 1 1 Brix domain Abhydrolase_6 PF12697.7 KXS15790.1 - 3.4e-20 73.6 0.8 4.5e-20 73.2 0.8 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXS15790.1 - 4.1e-19 69.2 0.0 1.3e-17 64.3 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXS15790.1 - 3.6e-16 59.2 0.0 5.3e-16 58.6 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.20 KXS15790.1 - 2.2e-07 30.8 0.2 1e-06 28.6 0.2 2.0 2 1 0 2 2 2 1 Putative esterase DLH PF01738.18 KXS15790.1 - 0.0018 17.8 0.0 0.032 13.8 0.0 2.2 2 0 0 2 2 2 1 Dienelactone hydrolase family Thioesterase PF00975.20 KXS15790.1 - 0.014 15.5 0.0 0.027 14.6 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_2 PF02230.16 KXS15790.1 - 0.052 13.3 0.0 6.6 6.5 0.0 2.8 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase CP_ATPgrasp_1 PF04174.13 KXS15790.1 - 0.15 11.0 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 A circularly permuted ATPgrasp GTP_cyclohydroI PF01227.22 KXS15791.1 - 1.1e-72 243.2 0.1 1.5e-72 242.8 0.1 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 KXS15791.1 - 0.16 12.1 0.0 0.31 11.2 0.0 1.4 1 0 0 1 1 1 0 QueF-like protein Exc PF07825.11 KXS15793.1 - 0.028 14.4 0.0 0.054 13.5 0.0 1.5 1 0 0 1 1 1 0 Excisionase-like protein Lactamase_B_2 PF12706.7 KXS15794.1 - 1.2e-11 44.6 0.1 4.3e-06 26.4 0.0 2.5 2 1 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KXS15794.1 - 1.7e-10 41.2 0.1 4.9e-10 39.8 0.1 1.7 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_4 PF13691.6 KXS15794.1 - 5.3e-06 26.0 0.0 1.3e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 tRNase Z endonuclease Cu2_monoox_C PF03712.15 KXS15796.1 - 6.1e-10 38.8 1.3 3.7e-08 33.0 1.3 2.2 1 1 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain Cu2_monooxygen PF01082.20 KXS15796.1 - 2.6e-05 24.5 0.0 8.5e-05 22.8 0.0 1.9 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain DOMON PF03351.17 KXS15796.1 - 3.9e-05 23.9 0.0 8.1e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 DOMON domain Vps5 PF09325.10 KXS15797.1 - 4.8e-07 29.6 0.4 7.4e-07 29.0 0.4 1.3 1 0 0 1 1 1 1 Vps5 C terminal like Adeno_PIX PF03955.14 KXS15797.1 - 0.21 11.8 4.7 0.21 11.8 2.0 2.3 1 1 1 2 2 2 0 Adenovirus hexon-associated protein (IX) AMP-binding PF00501.28 KXS15798.1 - 8.9e-64 215.6 0.0 1.9e-63 214.6 0.0 1.5 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXS15798.1 - 2.9e-08 34.6 0.0 6e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Herpes_DNAp_acc PF04929.12 KXS15798.1 - 0.66 8.9 2.9 1 8.3 2.9 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor F-box-like PF12937.7 KXS15800.1 - 2e-08 34.0 0.2 6.2e-08 32.4 0.0 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KXS15800.1 - 6e-07 29.2 2.8 7.5e-07 28.9 0.0 2.4 2 0 0 2 2 2 1 F-box domain Sel1 PF08238.12 KXS15801.1 - 7.5e-06 26.5 0.2 0.017 15.8 0.1 2.3 2 0 0 2 2 2 2 Sel1 repeat Abhydrolase_1 PF00561.20 KXS15804.1 - 1.4e-15 57.6 0.0 4.3e-12 46.2 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXS15804.1 - 2.6e-12 47.8 2.7 2.6e-12 47.8 2.7 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXS15804.1 - 4.8e-09 35.8 0.0 1.4e-06 27.8 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Thioesterase PF00975.20 KXS15804.1 - 1.9e-06 28.2 0.0 2.8e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Esterase PF00756.20 KXS15804.1 - 0.0023 17.6 0.1 0.0032 17.1 0.1 1.2 1 0 0 1 1 1 1 Putative esterase FSH1 PF03959.13 KXS15804.1 - 0.0023 17.6 0.0 1.8 8.2 0.0 2.1 2 0 0 2 2 2 2 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 KXS15804.1 - 0.0029 17.5 0.0 0.0042 16.9 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Ndr PF03096.14 KXS15804.1 - 0.0091 14.7 0.0 0.014 14.2 0.0 1.2 1 0 0 1 1 1 1 Ndr family Ser_hydrolase PF06821.13 KXS15804.1 - 0.024 14.5 0.0 0.047 13.6 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase Palm_thioest PF02089.15 KXS15804.1 - 0.057 13.2 0.0 0.08 12.8 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Peptidase_S9 PF00326.21 KXS15804.1 - 0.16 11.4 0.0 4.8 6.6 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family zf-C2H2_2 PF12756.7 KXS15805.1 - 2.5e-34 117.6 4.9 2.7e-26 91.9 0.0 3.2 3 0 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 KXS15805.1 - 4.9e-12 45.8 13.3 3.2e-07 30.5 4.5 3.4 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KXS15805.1 - 7.8e-06 26.1 4.0 7.8e-06 26.1 4.0 2.8 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KXS15805.1 - 0.0035 18.0 6.0 4.3 8.4 0.3 3.8 3 0 0 3 3 3 1 C2H2-type zinc finger Macoilin PF09726.9 KXS15805.1 - 0.09 11.3 3.6 0.13 10.8 3.6 1.2 1 0 0 1 1 1 0 Macoilin family zf-LYAR PF08790.11 KXS15805.1 - 0.2 11.6 10.7 1.1 9.2 0.5 3.1 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger Ephrin_rec_like PF07699.13 KXS15805.1 - 0.88 9.4 5.9 14 5.5 0.7 3.1 3 0 0 3 3 3 0 Putative ephrin-receptor like AKAP95 PF04988.12 KXS15805.1 - 6 7.1 7.8 1.6 9.0 0.9 2.6 2 1 1 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) Zn_clus PF00172.18 KXS15806.1 - 9.7e-05 22.4 8.8 0.00019 21.5 8.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 KXS15808.1 - 5.4e-09 36.0 10.4 8.6e-09 35.4 10.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 KXS15809.1 - 0.00014 21.9 1.9 0.00014 21.9 1.9 2.5 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXS15810.1 - 4.5e-15 55.4 0.2 8.6e-15 54.5 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXS15810.1 - 2.4e-07 30.7 9.3 2.4e-07 30.7 9.3 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2039 PF10217.9 KXS15811.1 - 1.9e-26 92.2 8.9 2.7e-26 91.7 8.9 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2039) PolC_DP2 PF03833.13 KXS15811.1 - 0.021 12.7 1.3 0.026 12.4 1.3 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zinc-ribbons_6 PF07191.12 KXS15811.1 - 0.12 12.4 7.1 0.96 9.5 6.2 2.0 2 0 0 2 2 2 0 zinc-ribbons DZR PF12773.7 KXS15811.1 - 0.32 11.1 8.3 0.47 10.5 2.2 2.3 1 1 1 2 2 2 0 Double zinc ribbon YhfH PF14149.6 KXS15811.1 - 0.55 10.3 5.4 0.24 11.4 1.6 2.3 2 0 0 2 2 2 0 YhfH-like protein Cript PF10235.9 KXS15811.1 - 1.4 9.5 11.3 2.6 8.7 11.3 1.6 1 1 0 1 1 1 0 Microtubule-associated protein CRIPT TctB PF07331.11 KXS15812.1 - 0.057 13.7 1.4 1.9 8.7 0.1 2.1 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family Pkinase PF00069.25 KXS15813.1 - 4.4e-15 55.8 0.0 4.5e-15 55.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS15813.1 - 7.6e-10 38.5 0.0 8.6e-10 38.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase TPR_2 PF07719.17 KXS15813.1 - 0.13 12.4 0.5 0.3 11.3 0.5 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat MIT PF04212.18 KXS15813.1 - 0.15 12.2 0.7 0.33 11.1 0.7 1.5 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain Sel1 PF08238.12 KXS15814.1 - 0.00022 21.8 2.0 0.018 15.7 0.1 3.0 3 0 0 3 3 3 2 Sel1 repeat RPA_interact_N PF14766.6 KXS15815.1 - 1.3e-06 28.0 5.8 3.2e-06 26.7 5.8 1.6 1 0 0 1 1 1 1 Replication protein A interacting N-terminal Cytochrom_B_N_2 PF13631.6 KXS15816.1 - 0.033 14.2 0.2 0.061 13.3 0.0 1.5 2 0 0 2 2 2 0 Cytochrome b(N-terminal)/b6/petB T2SSI PF02501.17 KXS15816.1 - 0.071 13.3 0.2 0.17 12.0 0.2 1.6 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein I SRP68 PF16969.5 KXS15819.1 - 3.6e-85 287.0 9.1 4.7e-85 286.7 9.1 1.1 1 0 0 1 1 1 1 RNA-binding signal recognition particle 68 Choline_transpo PF04515.12 KXS15820.1 - 1.1e-56 192.4 17.6 1.3e-56 192.2 17.6 1.0 1 0 0 1 1 1 1 Plasma-membrane choline transporter DUF4407 PF14362.6 KXS15820.1 - 1 8.6 4.4 1.9 7.8 4.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Stathmin PF00836.19 KXS15821.1 - 2.2e-10 40.6 102.9 0.025 14.5 19.8 7.3 2 2 5 7 7 7 7 Stathmin family Saccharop_dh_N PF04455.12 KXS15821.1 - 0.064 13.7 0.5 0.064 13.7 0.5 3.1 2 1 0 2 2 2 0 LOR/SDH bifunctional enzyme conserved region zf-RING_2 PF13639.6 KXS15822.1 - 2.9e-10 40.3 9.8 5e-10 39.5 9.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KXS15822.1 - 1.2e-08 34.5 2.6 2.4e-08 33.5 2.6 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KXS15822.1 - 7.1e-08 32.2 9.5 1.2e-07 31.5 9.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXS15822.1 - 2.5e-06 27.2 7.7 4.5e-06 26.4 7.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KXS15822.1 - 0.00014 22.1 7.9 0.0004 20.6 7.9 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KXS15822.1 - 0.00051 20.0 7.3 0.0012 18.9 7.3 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KXS15822.1 - 0.0048 16.7 6.3 0.0079 16.0 6.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXS15822.1 - 0.012 15.6 6.9 0.02 14.9 6.9 1.4 1 0 0 1 1 1 0 zinc-RING finger domain Prok-RING_4 PF14447.6 KXS15822.1 - 1.5 8.8 7.6 3.4 7.6 7.6 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 KXS15822.1 - 8.7 6.1 8.9 17 5.2 8.9 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type S1-P1_nuclease PF02265.16 KXS15823.1 - 6.8e-40 137.5 0.0 8.7e-40 137.1 0.0 1.1 1 0 0 1 1 1 1 S1/P1 Nuclease WD40 PF00400.32 KXS15824.1 - 4.2e-05 24.2 2.1 0.52 11.3 0.1 4.3 4 0 0 4 4 4 2 WD domain, G-beta repeat F-box-like PF12937.7 KXS15825.1 - 1.6e-14 53.5 0.4 2.7e-14 52.8 0.4 1.3 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXS15825.1 - 1.5e-08 34.3 0.1 2.4e-08 33.6 0.1 1.3 1 0 0 1 1 1 1 F-box domain MFS_1 PF07690.16 KXS15826.1 - 4.2e-16 58.8 5.3 4.2e-16 58.8 5.3 2.9 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF4131 PF13567.6 KXS15826.1 - 1 9.0 5.8 20 4.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) BT1 PF03092.16 KXS15826.1 - 1.4 7.0 12.6 0.041 12.1 3.9 2.0 2 0 0 2 2 2 0 BT1 family MARVEL PF01284.23 KXS15826.1 - 9.8 6.2 18.1 17 5.4 3.4 2.6 1 1 1 2 2 2 0 Membrane-associating domain MFS_1 PF07690.16 KXS15827.1 - 5.8e-35 120.8 51.1 1e-33 116.8 51.1 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Fzo_mitofusin PF04799.13 KXS15827.1 - 0.13 11.8 0.2 2.6 7.6 0.0 2.3 2 0 0 2 2 2 0 fzo-like conserved region DUF5464 PF17552.2 KXS15827.1 - 1.1 9.6 7.8 0.12 12.6 0.8 3.0 2 0 0 2 2 2 0 Family of unknown function (DUF5464) FAP PF07174.11 KXS15828.1 - 1.1 8.6 13.0 1.3 8.4 13.0 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) TPR_12 PF13424.6 KXS15829.1 - 2.4e-270 873.6 123.7 1.1e-16 60.8 2.1 21.0 9 4 14 25 25 25 23 Tetratricopeptide repeat TPR_10 PF13374.6 KXS15829.1 - 2.5e-262 841.0 93.3 3.6e-12 45.7 0.1 33.2 33 0 0 33 33 33 31 Tetratricopeptide repeat TPR_7 PF13176.6 KXS15829.1 - 6.3e-117 373.4 76.7 0.00037 20.3 0.1 31.5 32 0 0 32 32 31 27 Tetratricopeptide repeat TPR_1 PF00515.28 KXS15829.1 - 1.7e-98 318.8 69.4 0.0001 22.0 0.1 31.4 32 0 0 32 32 32 24 Tetratricopeptide repeat TPR_8 PF13181.6 KXS15829.1 - 9.4e-69 222.0 94.4 0.0027 17.8 0.1 31.0 32 0 0 32 32 31 18 Tetratricopeptide repeat TPR_14 PF13428.6 KXS15829.1 - 2e-57 186.9 66.5 0.22 12.4 0.2 32.0 16 9 17 33 33 32 15 Tetratricopeptide repeat TPR_2 PF07719.17 KXS15829.1 - 4.3e-56 182.6 73.0 0.069 13.3 0.1 31.5 32 0 0 32 32 32 13 Tetratricopeptide repeat TPR_19 PF14559.6 KXS15829.1 - 6e-48 161.2 68.8 0.00059 20.3 0.1 20.6 12 6 7 21 21 21 14 Tetratricopeptide repeat TPR_MalT PF17874.1 KXS15829.1 - 1e-41 143.4 53.5 6e-05 22.6 0.5 13.3 2 1 10 14 14 14 12 MalT-like TPR region Pkinase PF00069.25 KXS15829.1 - 9.1e-37 126.8 0.0 3.7e-35 121.6 0.0 3.8 5 0 0 5 5 5 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS15829.1 - 2.1e-36 125.5 0.0 4.2e-23 81.9 0.0 2.5 1 1 0 2 2 2 2 Protein tyrosine kinase ANAPC3 PF12895.7 KXS15829.1 - 1.6e-24 85.9 33.6 0.093 13.0 0.0 17.3 9 5 13 23 23 23 6 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.20 KXS15829.1 - 2.6e-23 80.6 41.1 1.4 9.4 0.0 24.9 28 0 0 28 28 25 2 PPR repeat TPR_6 PF13174.6 KXS15829.1 - 4.8e-21 73.9 81.9 0.091 13.4 0.0 28.1 32 0 0 32 32 30 3 Tetratricopeptide repeat TPR_16 PF13432.6 KXS15829.1 - 5.9e-14 52.4 56.9 0.65 10.7 0.0 20.4 16 8 5 21 21 21 3 Tetratricopeptide repeat Sel1 PF08238.12 KXS15829.1 - 1.5e-08 35.1 14.2 7.1e-05 23.3 0.3 7.7 7 0 0 7 7 5 2 Sel1 repeat TPR_5 PF12688.7 KXS15829.1 - 1.5e-07 31.6 28.3 8.3 6.7 0.0 14.8 13 5 0 15 15 15 0 Tetratrico peptide repeat BTAD PF03704.17 KXS15829.1 - 7.4e-07 29.7 66.7 1.1 9.6 0.6 17.4 5 4 11 18 18 17 3 Bacterial transcriptional activator domain TPR_17 PF13431.6 KXS15829.1 - 2.4e-06 27.5 59.3 2 9.0 0.1 21.6 28 0 0 28 28 24 1 Tetratricopeptide repeat Head_binding PF09008.10 KXS15829.1 - 0.00098 19.4 14.7 16 5.8 0.0 11.1 13 1 2 15 15 11 0 Head binding Kinase-like PF14531.6 KXS15829.1 - 0.0056 16.0 0.2 0.024 14.0 0.2 1.9 1 1 0 1 1 1 1 Kinase-like DUF3896 PF13035.6 KXS15829.1 - 0.015 15.4 51.4 3.4 7.9 0.2 18.8 17 4 7 24 24 22 0 Protein of unknown function (DUF3896) TPR_11 PF13414.6 KXS15829.1 - 0.015 14.9 97.8 1.6 8.5 0.3 24.2 28 0 0 28 28 27 0 TPR repeat GH101_N PF17995.1 KXS15829.1 - 0.064 12.9 6.3 30 4.2 0.0 6.7 8 1 0 9 9 7 0 Endo-alpha-N-acetylgalactosaminidase N-terminal ATG16 PF08614.11 KXS15829.1 - 2.7 8.2 43.5 0.062 13.5 0.2 10.8 6 3 5 14 14 14 0 Autophagy protein 16 (ATG16) TPR_20 PF14561.6 KXS15829.1 - 3 8.2 60.9 26 5.3 0.0 19.1 8 5 13 24 24 21 0 Tetratricopeptide repeat PPR_2 PF13041.6 KXS15829.1 - 4.2 7.6 34.7 1.2e+02 3.0 0.0 16.1 23 0 0 23 23 20 0 PPR repeat family RPE65 PF03055.15 KXS15831.1 - 1.4e-77 261.9 0.2 1.2e-50 173.1 0.1 2.0 1 1 1 2 2 2 2 Retinal pigment epithelial membrane protein RPE65 PF03055.15 KXS15832.1 - 3e-111 372.9 0.0 3.5e-111 372.7 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein NAD_binding_8 PF13450.6 KXS15833.1 - 2.8e-06 27.5 0.0 4.8e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain AAA PF00004.29 KXS15834.1 - 3.6e-35 121.3 0.0 6.8e-35 120.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KXS15834.1 - 9.6e-15 54.1 0.3 2.5e-14 52.8 0.3 1.7 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 KXS15834.1 - 8.1e-05 22.4 0.0 0.00018 21.3 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KXS15834.1 - 0.00021 21.3 0.0 0.00044 20.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KXS15834.1 - 0.00023 21.6 0.1 0.00074 19.9 0.0 1.9 2 0 0 2 2 1 1 AAA ATPase domain AAA_22 PF13401.6 KXS15834.1 - 0.0006 20.1 0.1 0.0032 17.8 0.1 2.3 2 1 0 2 2 1 1 AAA domain AAA_25 PF13481.6 KXS15834.1 - 0.0008 19.0 0.9 0.022 14.3 0.3 3.0 2 1 1 3 3 3 1 AAA domain TIP49 PF06068.13 KXS15834.1 - 0.00086 18.6 0.1 0.0031 16.8 0.0 1.8 2 0 0 2 2 2 1 TIP49 P-loop domain Mg_chelatase PF01078.21 KXS15834.1 - 0.001 18.5 0.0 0.002 17.5 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 KXS15834.1 - 0.0014 18.4 0.0 0.0026 17.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KXS15834.1 - 0.0033 17.5 0.0 0.0059 16.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KXS15834.1 - 0.0042 16.8 0.0 0.0092 15.7 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_2 PF07724.14 KXS15834.1 - 0.0057 16.8 0.0 0.011 15.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) LisH PF08513.11 KXS15834.1 - 0.0068 16.3 0.0 0.016 15.2 0.0 1.6 1 0 0 1 1 1 1 LisH RNA_helicase PF00910.22 KXS15834.1 - 0.0075 16.6 0.0 0.017 15.5 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_7 PF12775.7 KXS15834.1 - 0.018 14.5 0.0 0.041 13.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_18 PF13238.6 KXS15834.1 - 0.02 15.4 1.5 0.02 15.4 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_28 PF13521.6 KXS15834.1 - 0.021 15.1 0.0 0.076 13.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KXS15834.1 - 0.032 14.1 0.0 0.077 12.9 0.0 1.7 1 0 0 1 1 1 0 NACHT domain AAA_33 PF13671.6 KXS15834.1 - 0.035 14.3 0.0 0.073 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 KXS15834.1 - 0.037 13.7 0.0 1.5 8.5 0.0 2.7 3 0 0 3 3 3 0 Sigma-54 interaction domain Parvo_NS1 PF01057.17 KXS15834.1 - 0.037 13.1 0.1 0.06 12.4 0.1 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_3 PF07726.11 KXS15834.1 - 0.059 13.2 0.0 0.25 11.2 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 KXS15834.1 - 0.079 13.0 0.0 0.2 11.7 0.0 1.7 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain TsaE PF02367.17 KXS15834.1 - 0.089 12.8 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase PF06745.13 KXS15834.1 - 0.18 11.1 0.1 4.5 6.6 0.1 2.2 1 1 1 2 2 2 0 KaiC AA_permease_2 PF13520.6 KXS15835.1 - 7.3e-48 163.4 44.6 9.3e-48 163.1 44.6 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXS15835.1 - 3.4e-18 65.5 38.8 4.5e-18 65.1 38.8 1.1 1 0 0 1 1 1 1 Amino acid permease Phage_holin_3_6 PF07332.11 KXS15835.1 - 0.075 13.1 0.1 0.075 13.1 0.1 4.2 4 0 0 4 4 4 0 Putative Actinobacterial Holin-X, holin superfamily III SAD_SRA PF02182.17 KXS15836.1 - 3.3e-19 69.1 0.2 3.4e-19 69.1 0.2 1.0 1 0 0 1 1 1 1 SAD/SRA domain SAD_SRA PF02182.17 KXS15837.1 - 3.2e-55 186.1 0.1 4.1e-55 185.8 0.1 1.1 1 0 0 1 1 1 1 SAD/SRA domain End_N_terminal PF12218.8 KXS15837.1 - 0.043 13.5 0.0 0.098 12.4 0.0 1.6 1 0 0 1 1 1 0 N terminal extension of bacteriophage endosialidase Pap_E4 PF02711.14 KXS15837.1 - 1.1 10.3 12.9 13 6.8 12.9 2.2 1 1 0 1 1 1 0 E4 protein TFIIF_alpha PF05793.12 KXS15837.1 - 2.6 6.5 7.3 3.6 6.1 7.3 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Pkinase PF00069.25 KXS15838.1 - 3.3e-69 233.2 0.0 4.2e-69 232.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS15838.1 - 2e-32 112.5 0.0 1e-31 110.2 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXS15838.1 - 6e-09 35.6 0.0 6.5e-05 22.4 0.0 2.3 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 KXS15838.1 - 2.5e-06 27.6 0.0 0.00017 21.6 0.3 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KXS15838.1 - 0.0012 17.9 0.1 0.0016 17.4 0.1 1.3 1 1 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 KXS15838.1 - 0.0022 17.7 0.3 2 8.0 0.0 2.3 1 1 1 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 KXS15838.1 - 0.0047 15.8 0.0 0.0071 15.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 KXS15838.1 - 0.0059 16.2 0.1 0.014 15.0 0.1 1.6 1 1 0 1 1 1 1 RIO1 family Kdo PF06293.14 KXS15838.1 - 0.018 14.4 0.0 0.026 13.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 KXS15838.1 - 0.048 12.7 0.0 0.089 11.8 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 DUF413 PF04219.12 KXS15839.1 - 0.093 12.8 0.5 0.59 10.2 0.5 2.4 1 0 0 1 1 1 0 Protein of unknown function, DUF Fib_alpha PF08702.10 KXS15839.1 - 0.64 10.2 33.6 0.21 11.8 2.3 5.8 2 2 4 6 6 6 0 Fibrinogen alpha/beta chain family UAA PF08449.11 KXS15840.1 - 1.6e-07 30.9 12.3 2.2e-07 30.4 12.3 1.2 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.16 KXS15840.1 - 2.6e-06 27.0 15.0 5.9e-05 22.6 15.0 2.0 1 1 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KXS15840.1 - 7e-06 26.2 5.8 7e-06 26.2 5.8 2.3 2 0 0 2 2 2 2 EamA-like transporter family zf-RING_2 PF13639.6 KXS15841.1 - 4.4e-12 46.1 8.9 6.8e-12 45.5 8.9 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KXS15841.1 - 1.5e-09 37.4 2.2 3.3e-09 36.3 2.2 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KXS15841.1 - 2.8e-08 33.5 8.1 4.4e-08 32.8 8.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXS15841.1 - 1.4e-07 31.3 5.7 2.1e-07 30.7 5.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXS15841.1 - 3.1e-07 30.3 4.7 3.1e-07 30.3 4.7 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 KXS15841.1 - 7.4e-06 26.2 10.8 5e-05 23.5 10.2 2.1 1 1 1 2 2 2 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KXS15841.1 - 1.8e-05 24.6 3.7 2.7e-05 24.0 3.7 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KXS15841.1 - 0.0025 17.6 5.5 0.0039 17.0 5.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KXS15841.1 - 0.0025 17.8 4.3 0.0049 16.9 4.3 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger DUF998 PF06197.13 KXS15841.1 - 0.027 14.1 2.1 0.24 11.0 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF998) Prok-RING_4 PF14447.6 KXS15841.1 - 0.046 13.6 8.2 0.026 14.4 3.9 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 KXS15841.1 - 0.049 13.3 4.7 0.091 12.4 4.7 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-Nse PF11789.8 KXS15841.1 - 0.082 12.7 4.9 0.2 11.5 4.9 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.6 KXS15841.1 - 0.48 10.6 8.5 1 9.6 8.5 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING RINGv PF12906.7 KXS15841.1 - 6 7.1 6.2 9.4 6.5 5.8 1.6 1 1 0 1 1 1 0 RING-variant domain ChaC PF04752.12 KXS15842.1 - 1.4e-54 184.8 0.0 1.9e-54 184.4 0.0 1.2 1 0 0 1 1 1 1 ChaC-like protein HTH_Tnp_1 PF01527.20 KXS15842.1 - 0.0037 17.6 0.0 0.0083 16.4 0.0 1.6 1 0 0 1 1 1 1 Transposase GGACT PF06094.12 KXS15842.1 - 0.0059 17.2 0.2 0.036 14.7 0.1 2.2 2 1 0 2 2 2 1 Gamma-glutamyl cyclotransferase, AIG2-like Suc_Fer-like PF06999.12 KXS15843.1 - 2e-37 129.0 0.0 2.4e-37 128.7 0.0 1.0 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Pkinase PF00069.25 KXS15844.1 - 2.8e-29 102.3 0.0 7.1e-29 101.0 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS15844.1 - 1e-12 47.9 0.0 4.3e-10 39.3 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KXS15844.1 - 0.00045 20.2 2.8 0.00096 19.1 2.2 1.8 2 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KXS15844.1 - 0.00067 19.1 0.1 0.001 18.5 0.1 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KXS15844.1 - 0.0017 17.2 0.0 0.0021 16.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase zf-ANAPC11 PF12861.7 KXS15844.1 - 0.016 15.3 0.0 0.028 14.5 0.0 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Haspin_kinase PF12330.8 KXS15844.1 - 0.032 13.2 0.2 0.055 12.4 0.2 1.3 1 0 0 1 1 1 0 Haspin like kinase domain NPP1 PF05630.11 KXS15846.1 - 8.6e-40 136.9 0.1 1.1e-39 136.6 0.1 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) NPP1 PF05630.11 KXS15847.1 - 6.6e-14 52.5 0.5 5.7e-13 49.4 0.3 1.9 1 1 1 2 2 2 2 Necrosis inducing protein (NPP1) NPP1 PF05630.11 KXS15849.1 - 1e-44 153.0 0.0 1.2e-44 152.8 0.0 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) Phycobilisome PF00502.19 KXS15851.1 - 0.055 13.4 1.1 0.088 12.7 1.1 1.3 1 0 0 1 1 1 0 Phycobilisome protein DUF1664 PF07889.12 KXS15851.1 - 0.2 11.7 4.8 0.33 11.0 0.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Kisspeptin PF15152.6 KXS15851.1 - 0.39 11.5 1.9 1.1 10.1 0.0 2.3 2 1 0 2 2 2 0 Kisspeptin NDC10_II PF16787.5 KXS15853.1 - 3.9e-09 36.0 0.0 1.6e-07 30.7 0.0 2.0 2 0 0 2 2 2 2 Centromere DNA-binding protein complex CBF3 subunit, domain 2 Ribosomal_S5_C PF03719.15 KXS15853.1 - 0.12 11.9 0.0 1.3 8.5 0.0 2.5 1 1 2 3 3 3 0 Ribosomal protein S5, C-terminal domain Hexapep PF00132.24 KXS15853.1 - 0.12 12.1 0.0 0.52 10.1 0.0 1.9 2 0 0 2 2 2 0 Bacterial transferase hexapeptide (six repeats) BTB_2 PF02214.22 KXS15854.1 - 1.9e-17 63.4 0.0 3.6e-17 62.5 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 KXS15854.1 - 0.036 14.2 0.0 0.056 13.5 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain F-box-like PF12937.7 KXS15855.1 - 7e-05 22.6 0.4 0.00022 21.0 0.4 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXS15855.1 - 0.06 13.2 0.4 0.06 13.2 0.4 2.5 3 1 0 3 3 3 0 F-box domain dCMP_cyt_deam_1 PF00383.23 KXS15856.1 - 4.7e-17 61.7 0.0 1.9e-16 59.8 0.0 1.8 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KXS15856.1 - 2.8e-12 46.6 0.0 4.2e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 KXS15856.1 - 0.0093 16.0 0.0 0.071 13.2 0.0 2.0 2 0 0 2 2 2 1 Bd3614-like deaminase RCC1_2 PF13540.6 KXS15856.1 - 0.056 13.3 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Regulator of chromosome condensation (RCC1) repeat F-box-like PF12937.7 KXS15857.1 - 1.4e-07 31.3 0.7 3.7e-07 29.9 0.7 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXS15857.1 - 1.7e-06 27.8 1.0 8e-06 25.6 0.8 2.1 2 0 0 2 2 2 1 F-box domain SelP_N PF04592.14 KXS15860.1 - 4.4 6.6 9.1 6.6 6.1 9.1 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region COX6B PF02297.17 KXS15861.1 - 9.2e-17 61.1 0.3 4e-07 30.2 0.1 2.3 2 0 0 2 2 2 2 Cytochrome oxidase c subunit VIb SOG2 PF10428.9 KXS15861.1 - 0.028 13.6 6.2 0.028 13.6 6.2 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DUF908 PF06012.12 KXS15861.1 - 0.43 9.9 7.3 0.55 9.6 7.3 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Ndc1_Nup PF09531.10 KXS15861.1 - 0.67 8.6 7.1 0.78 8.4 7.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PRCC PF10253.9 KXS15861.1 - 1.8 9.3 11.8 0.29 11.9 7.7 1.7 1 1 1 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting Apt1 PF10351.9 KXS15861.1 - 6 5.6 6.8 7.5 5.3 6.8 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain BTB_2 PF02214.22 KXS15862.1 - 6.7e-10 39.2 0.0 7.6e-09 35.8 0.0 2.3 2 0 0 2 2 2 1 BTB/POZ domain AhpC-TSA PF00578.21 KXS15864.1 - 9.4e-35 119.2 0.0 1.2e-34 118.9 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KXS15864.1 - 2.2e-14 53.4 0.0 3.1e-14 52.9 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 KXS15864.1 - 3.6e-12 45.9 0.1 1.1e-11 44.4 0.1 1.8 2 0 0 2 2 2 1 C-terminal domain of 1-Cys peroxiredoxin SCO1-SenC PF02630.14 KXS15864.1 - 0.053 13.4 0.0 0.097 12.6 0.0 1.4 1 0 0 1 1 1 0 SCO1/SenC Abhydrolase_4 PF08386.10 KXS15865.1 - 0.13 12.4 0.0 0.39 10.9 0.0 1.8 2 0 0 2 2 2 0 TAP-like protein Granulin PF00396.18 KXS15866.1 - 0.076 13.4 3.1 0.13 12.6 3.1 1.4 1 0 0 1 1 1 0 Granulin EutB PF06751.11 KXS15867.1 - 2.8e-128 428.5 0.0 3.7e-128 428.0 0.0 1.1 1 0 0 1 1 1 1 Ethanolamine ammonia lyase large subunit (EutB) EutC PF05985.11 KXS15867.1 - 5.2e-15 55.4 0.5 5.6e-07 29.1 0.6 2.4 2 0 0 2 2 2 2 Ethanolamine ammonia-lyase light chain (EutC) FAM72 PF14976.6 KXS15868.1 - 5.6e-53 179.0 0.9 7.6e-53 178.6 0.9 1.1 1 0 0 1 1 1 1 FAM72 protein BTB_2 PF02214.22 KXS15871.1 - 7.9e-16 58.2 0.0 7.8e-07 29.4 0.0 2.3 2 0 0 2 2 2 2 BTB/POZ domain Glyco_tran_10_N PF17039.5 KXS15871.1 - 0.017 15.6 0.0 0.031 14.7 0.0 1.4 1 0 0 1 1 1 0 Fucosyltransferase, N-terminal PriCT_1 PF08708.11 KXS15871.1 - 0.041 13.6 0.0 2.7 7.8 0.0 2.5 2 0 0 2 2 2 0 Primase C terminal 1 (PriCT-1) Fucosidase_C PF16757.5 KXS15871.1 - 0.051 14.1 0.0 0.29 11.7 0.0 2.0 2 0 0 2 2 2 0 Alpha-L-fucosidase C-terminal domain APG12 PF04110.13 KXS15871.1 - 0.059 13.8 0.0 0.53 10.7 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin-like autophagy protein Apg12 Jacalin PF01419.17 KXS15872.1 - 1.4e-06 28.3 0.2 2.9e-06 27.2 0.2 1.5 1 0 0 1 1 1 1 Jacalin-like lectin domain DUF5046 PF16465.5 KXS15872.1 - 0.053 13.0 0.2 0.053 13.0 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5046) MGC-24 PF05283.11 KXS15873.1 - 0.00028 21.3 1.6 0.00028 21.3 1.6 2.2 2 0 0 2 2 2 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin Podoplanin PF05808.11 KXS15873.1 - 0.011 15.9 0.2 0.027 14.6 0.2 1.6 1 0 0 1 1 1 0 Podoplanin DUF4366 PF14283.6 KXS15873.1 - 0.085 12.9 0.1 0.32 11.0 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) MSA-2c PF12238.8 KXS15873.1 - 0.21 11.6 2.1 0.35 10.8 2.1 1.3 1 0 0 1 1 1 0 Merozoite surface antigen 2c PRR18 PF15671.5 KXS15873.1 - 0.65 9.8 12.1 1.6 8.6 12.1 1.7 1 0 0 1 1 1 0 Proline-rich protein family 18 Mating_N PF12731.7 KXS15874.1 - 0.0007 19.6 0.0 0.00088 19.3 0.0 1.1 1 0 0 1 1 1 1 Mating-type protein beta 1 Spore_YhaL PF14147.6 KXS15874.1 - 0.073 12.8 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Sporulation protein YhaL Pkinase PF00069.25 KXS15877.1 - 3.9e-34 118.2 0.0 9.5e-16 57.9 0.0 2.8 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXS15877.1 - 2e-13 50.2 0.0 2.4e-06 27.1 0.0 3.2 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXS15877.1 - 0.1 11.4 0.0 0.2 10.4 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Prolactin_RP PF15172.6 KXS15878.1 - 0.84 9.3 3.5 0.42 10.3 0.6 1.9 2 0 0 2 2 2 0 Prolactin-releasing peptide ADH_N_2 PF16884.5 KXS15879.1 - 4.7e-18 65.1 0.0 1.1e-17 63.8 0.0 1.7 1 1 0 1 1 1 1 N-terminal domain of oxidoreductase CMAS PF02353.20 KXS15880.1 - 2.9e-54 184.2 0.0 3.6e-43 147.8 0.0 2.1 2 0 0 2 2 2 2 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 KXS15880.1 - 2.4e-05 24.9 0.0 4e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXS15880.1 - 0.00015 22.3 0.0 0.00027 21.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain eIF-5a PF01287.20 KXS15880.1 - 0.034 14.3 0.0 0.079 13.1 0.0 1.6 1 0 0 1 1 1 0 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold MTS PF05175.14 KXS15880.1 - 0.12 12.0 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_23 PF13489.6 KXS15880.1 - 0.12 12.2 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DUF1365 PF07103.11 KXS15881.1 - 4.6e-50 170.5 0.0 5.9e-50 170.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1365) eRF1_2 PF03464.15 KXS15882.1 - 3.6e-28 98.5 0.0 1.6e-21 77.0 0.0 2.4 1 1 1 2 2 2 2 eRF1 domain 2 baeRF_family10 PF18854.1 KXS15882.1 - 8.3e-10 39.1 0.1 1.8e-09 38.0 0.1 1.6 2 0 0 2 2 2 1 Bacterial archaeo-eukaryotic release factor family 10 acVLRF1 PF18859.1 KXS15882.1 - 7.9e-08 32.7 0.3 1.8e-07 31.5 0.1 1.7 2 0 0 2 2 2 1 Actinobacteria/chloroflexi VLRF1 release factor eRF1_1 PF03463.15 KXS15882.1 - 0.00022 21.2 0.0 0.00034 20.6 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 Reeler PF02014.16 KXS15883.1 - 1.6e-06 28.9 0.0 2.7e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Reeler domain TrbC PF04956.13 KXS15883.1 - 0.24 11.6 0.1 0.24 11.6 0.1 2.7 2 1 0 2 2 2 0 TrbC/VIRB2 family Peptidase_M28 PF04389.17 KXS15885.1 - 2.2e-33 115.7 0.0 3.3e-33 115.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KXS15885.1 - 0.0046 16.7 0.0 0.0066 16.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 DUF1126 PF06565.12 KXS15887.1 - 1.3e-83 275.7 0.0 2.5e-31 107.6 0.0 3.2 3 0 0 3 3 3 3 DUF1126 PH-like domain Allantoicase PF03561.15 KXS15888.1 - 1.8e-80 268.0 0.0 2.8e-43 147.3 0.0 2.1 2 0 0 2 2 2 2 Allantoicase repeat zf_C2H2_ZHX PF18387.1 KXS15889.1 - 0.0089 15.6 1.2 0.017 14.7 1.2 1.4 1 0 0 1 1 1 1 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2 PF00096.26 KXS15889.1 - 0.028 14.9 6.1 0.076 13.5 6.1 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_3rep PF18868.1 KXS15889.1 - 0.096 13.4 0.2 0.18 12.5 0.2 1.4 1 0 0 1 1 1 0 Zinc finger C2H2-type, 3 repeats DUF629 PF04780.12 KXS15889.1 - 0.31 9.5 0.7 0.48 8.9 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF629) Rho_GDI PF02115.17 KXS15890.1 - 1.1e-50 172.1 0.2 2e-50 171.3 0.2 1.4 1 1 0 1 1 1 1 RHO protein GDP dissociation inhibitor Bax1-I PF01027.20 KXS15892.1 - 0.0021 17.9 2.5 0.003 17.4 2.5 1.2 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 CbiD PF01888.17 KXS15892.1 - 0.079 12.3 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 CbiD LYRIC PF15686.5 KXS15893.1 - 0.042 13.4 0.8 0.077 12.6 0.0 1.7 2 0 0 2 2 2 0 Lysine-rich CEACAM1 co-isolated protein family DUF4381 PF14316.6 KXS15894.1 - 0.072 13.3 1.3 0.14 12.4 1.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF3262 PF11660.8 KXS15894.1 - 0.19 12.1 4.1 2 8.9 2.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3262) zf-RING_2 PF13639.6 KXS15895.1 - 1.2e-12 48.0 5.0 1.6e-12 47.5 5.0 1.2 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KXS15895.1 - 1.6e-09 37.5 1.9 2.1e-09 37.1 1.9 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXS15895.1 - 5e-08 32.7 4.2 4.7e-07 29.5 4.2 2.0 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXS15895.1 - 1.2e-07 31.6 1.6 1.6e-07 31.1 1.6 1.2 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KXS15895.1 - 3.2e-07 30.2 3.4 3.2e-07 30.2 3.4 1.7 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_11 PF17123.5 KXS15895.1 - 3.6e-07 29.8 5.1 3.6e-07 29.8 5.1 1.6 2 0 0 2 2 2 1 RING-like zinc finger zf-rbx1 PF12678.7 KXS15895.1 - 1.3e-06 28.6 5.5 9.5e-06 25.8 5.5 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 KXS15895.1 - 6.3e-06 25.9 3.6 1.6e-05 24.7 3.3 1.7 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 KXS15895.1 - 1.5e-05 24.7 1.4 2.4e-05 24.1 1.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KXS15895.1 - 0.00071 19.2 3.3 0.0012 18.4 3.3 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 KXS15895.1 - 0.0015 18.5 1.8 0.0026 17.8 1.8 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 KXS15895.1 - 0.047 13.8 2.3 0.058 13.6 0.2 2.0 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING RINGv PF12906.7 KXS15895.1 - 0.32 11.1 1.8 0.89 9.7 1.8 1.8 1 1 0 1 1 1 0 RING-variant domain FANCL_C PF11793.8 KXS15895.1 - 0.37 11.0 4.7 3.7 7.8 4.7 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain Prok-RING_1 PF14446.6 KXS15895.1 - 0.52 10.3 5.4 0.28 11.1 1.4 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-C3H2C3 PF17122.5 KXS15895.1 - 1.9 8.6 7.2 0.32 11.1 2.7 2.0 2 1 0 2 2 2 0 Zinc-finger GMC_oxred_N PF00732.19 KXS15896.1 - 5e-75 252.6 0.0 7.6e-75 252.0 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXS15896.1 - 4.2e-40 137.6 0.1 7.8e-40 136.7 0.1 1.5 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KXS15896.1 - 0.00027 21.1 0.0 0.00068 19.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXS15896.1 - 0.0003 20.5 0.0 0.12 11.9 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KXS15896.1 - 0.00043 19.5 0.0 0.49 9.4 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 KXS15896.1 - 0.0013 17.9 0.0 0.0019 17.3 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 KXS15896.1 - 0.0088 15.3 0.0 0.019 14.2 0.0 1.5 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 KXS15896.1 - 0.016 14.4 0.0 0.069 12.4 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.19 KXS15897.1 - 9.3e-61 205.8 0.0 1.2e-60 205.4 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXS15897.1 - 2.5e-41 141.5 0.0 4.2e-41 140.8 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 KXS15897.1 - 2e-06 27.7 0.0 0.015 14.9 0.0 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KXS15897.1 - 0.00099 18.3 0.0 0.0014 17.7 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KXS15897.1 - 0.001 19.3 0.0 0.0021 18.2 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXS15897.1 - 0.0015 17.8 0.0 0.03 13.6 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXS15897.1 - 0.0044 16.1 0.0 0.64 9.0 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.17 KXS15897.1 - 0.027 13.7 0.0 0.054 12.7 0.0 1.4 1 0 0 1 1 1 0 Thi4 family FAD_binding_3 PF01494.19 KXS15897.1 - 0.07 12.4 0.0 1.6 7.9 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain TetR_C_16 PF17920.1 KXS15897.1 - 0.1 12.8 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain CTP_transf_1 PF01148.20 KXS15898.1 - 1.1e-40 140.1 5.5 1.1e-40 140.1 5.5 1.5 2 0 0 2 2 2 1 Cytidylyltransferase family SNARE_assoc PF09335.11 KXS15898.1 - 1.3 9.5 8.9 0.27 11.7 3.8 2.5 2 0 0 2 2 2 0 SNARE associated Golgi protein ECH_1 PF00378.20 KXS15899.1 - 1.6e-26 93.2 0.0 1.8e-26 93.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXS15899.1 - 3.4e-09 36.7 0.0 3.8e-09 36.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase adh_short PF00106.25 KXS15900.1 - 0.00047 19.7 0.1 0.041 13.3 0.3 2.9 3 0 0 3 3 3 2 short chain dehydrogenase Methyltransf_31 PF13847.6 KXS15901.1 - 6.4e-05 22.8 0.0 0.033 14.0 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 KXS15901.1 - 8.6e-05 23.1 0.2 0.013 16.1 0.2 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXS15901.1 - 0.00012 22.7 0.2 0.012 16.3 0.0 2.4 1 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXS15901.1 - 0.00019 21.3 0.0 0.00032 20.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXS15901.1 - 0.044 14.5 0.2 2 9.2 0.2 2.4 1 1 0 1 1 1 0 Methyltransferase domain Plant_tran PF04827.14 KXS15905.1 - 1.5e-05 24.7 0.0 2.3e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_4 PF13359.6 KXS15905.1 - 1.8e-05 24.4 0.1 2.6e-05 24.0 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Myb_DNA-bind_3 PF12776.7 KXS15906.1 - 0.0037 18.2 5.1 0.052 14.5 2.7 2.6 2 1 0 2 2 2 1 Myb/SANT-like DNA-binding domain TetR_C_1 PF02909.17 KXS15906.1 - 0.018 14.8 0.4 0.035 13.9 0.4 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Rab_eff_C PF04698.12 KXS15906.1 - 0.07 11.4 2.7 0.089 11.1 2.7 1.1 1 0 0 1 1 1 0 Rab effector MyRIP/melanophilin C-terminus LUD_dom PF02589.15 KXS15907.1 - 2.3e-20 73.1 0.0 2.8e-20 72.8 0.0 1.1 1 0 0 1 1 1 1 LUD domain DUF2628 PF10947.8 KXS15908.1 - 0.1 13.0 0.8 0.12 12.7 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2628) LUD_dom PF02589.15 KXS15909.1 - 8.6e-24 84.3 0.0 8.6e-24 84.3 0.0 1.6 2 0 0 2 2 2 1 LUD domain BCAS2 PF05700.11 KXS15909.1 - 0.026 14.2 1.2 0.045 13.4 1.2 1.3 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 2 (BCAS2) Hamartin PF04388.12 KXS15909.1 - 0.09 11.4 4.5 0.11 11.1 4.5 1.1 1 0 0 1 1 1 0 Hamartin protein DUF966 PF06136.13 KXS15909.1 - 1.1 8.9 5.3 1.5 8.5 5.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Ndc1_Nup PF09531.10 KXS15909.1 - 3.6 6.2 4.2 3.9 6.1 4.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup LRR_4 PF12799.7 KXS15911.1 - 2.6e-15 56.3 14.9 0.001 19.4 1.6 7.0 5 1 4 9 9 9 7 Leucine Rich repeats (2 copies) SH3_1 PF00018.28 KXS15911.1 - 2.2e-05 23.9 0.0 4.3e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KXS15911.1 - 0.0012 18.7 0.0 0.0025 17.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain LRR_8 PF13855.6 KXS15911.1 - 0.037 13.8 15.2 6.8 6.5 0.0 5.2 3 1 3 6 6 6 0 Leucine rich repeat DUF420 PF04238.12 KXS15912.1 - 0.0065 16.8 0.1 0.0098 16.2 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF420) DUF5323 PF17257.2 KXS15913.1 - 2 8.3 7.9 14 5.7 3.7 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5323) E1-E2_ATPase PF00122.20 KXS15914.1 - 4.5e-41 140.4 1.7 9.4e-41 139.3 1.7 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KXS15914.1 - 1.1e-33 116.4 17.6 1.9e-33 115.7 3.9 2.7 3 0 0 3 3 3 2 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KXS15914.1 - 7.8e-22 78.6 0.1 1e-11 45.6 0.0 2.9 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KXS15914.1 - 8.5e-20 70.6 0.0 2e-19 69.5 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KXS15914.1 - 1.3e-08 34.9 1.2 7.4e-08 32.4 1.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KXS15914.1 - 6.7e-05 23.4 0.0 0.025 15.0 0.0 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase DAGK_cat PF00781.24 KXS15914.1 - 0.072 12.7 0.4 13 5.4 0.0 2.8 3 0 0 3 3 3 0 Diacylglycerol kinase catalytic domain Abhydrolase_9_N PF15420.6 KXS15914.1 - 0.91 9.5 7.5 0.64 10.0 3.0 2.4 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus zf-CCHC PF00098.23 KXS15915.1 - 5.9e-06 26.1 0.5 1.1e-05 25.3 0.5 1.4 1 0 0 1 1 1 1 Zinc knuckle FoP_duplication PF13865.6 KXS15915.1 - 8.6 7.0 14.7 14 6.3 14.7 1.3 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 UAA PF08449.11 KXS15917.1 - 1.6e-55 188.5 8.2 1.9e-55 188.2 8.2 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 KXS15917.1 - 1.9e-08 34.5 31.6 2.5e-05 24.5 15.3 3.0 3 0 0 3 3 3 2 EamA-like transporter family CRT-like PF08627.10 KXS15917.1 - 7.2e-05 21.9 1.7 9.4e-05 21.5 0.7 1.6 1 1 1 2 2 2 1 CRT-like, chloroquine-resistance transporter-like TPT PF03151.16 KXS15917.1 - 0.62 9.4 11.0 11 5.2 11.0 2.1 1 1 0 1 1 1 0 Triose-phosphate Transporter family UAA PF08449.11 KXS15918.1 - 2.4e-56 191.2 10.6 3e-56 190.9 10.6 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 KXS15918.1 - 1.1e-10 41.8 29.8 7.1e-07 29.5 13.9 3.0 3 0 0 3 3 3 2 EamA-like transporter family SLC35F PF06027.12 KXS15918.1 - 4.9e-06 26.3 10.6 8.2e-06 25.5 10.6 1.3 1 0 0 1 1 1 1 Solute carrier family 35 CRT-like PF08627.10 KXS15918.1 - 0.0047 15.9 0.2 0.0047 15.9 0.2 1.8 2 0 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like Nuc_sug_transp PF04142.15 KXS15918.1 - 0.016 14.4 5.4 0.45 9.6 4.2 2.1 1 1 0 1 1 1 0 Nucleotide-sugar transporter TMEM234 PF10639.9 KXS15918.1 - 0.043 13.9 0.1 0.043 13.9 0.1 1.9 2 0 0 2 2 2 0 Putative transmembrane family 234 DUF2628 PF10947.8 KXS15918.1 - 8.8 6.8 15.2 0.41 11.0 0.3 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2628) Thioredoxin PF00085.20 KXS15919.1 - 2.3e-70 233.1 0.9 6.7e-34 116.0 0.0 3.6 4 0 0 4 4 4 3 Thioredoxin Thioredoxin_6 PF13848.6 KXS15919.1 - 3.4e-50 170.5 0.2 1.4e-35 122.9 0.1 3.5 2 2 2 4 4 4 3 Thioredoxin-like domain Calsequestrin PF01216.17 KXS15919.1 - 1e-13 51.1 1.3 6.6e-13 48.5 0.2 2.5 3 0 0 3 3 3 1 Calsequestrin OST3_OST6 PF04756.13 KXS15919.1 - 9.5e-11 41.6 0.5 0.041 13.2 0.0 4.1 3 1 0 4 4 4 3 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 KXS15919.1 - 2.5e-10 40.4 0.0 0.00014 22.0 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.6 KXS15919.1 - 2.9e-10 40.6 0.3 0.00078 19.9 0.1 3.9 3 2 0 3 3 3 2 Thioredoxin-like domain AhpC-TSA PF00578.21 KXS15919.1 - 9.7e-08 32.0 0.2 0.0044 16.9 0.0 3.5 2 1 0 3 3 3 2 AhpC/TSA family Thioredoxin_8 PF13905.6 KXS15919.1 - 1.1e-07 32.0 0.1 0.039 14.3 0.0 4.1 5 1 0 5 5 4 2 Thioredoxin-like Redoxin PF08534.10 KXS15919.1 - 0.00038 20.2 0.4 0.92 9.2 0.1 2.8 3 0 0 3 3 3 2 Redoxin Glutaredoxin PF00462.24 KXS15919.1 - 0.0061 16.8 0.5 14 6.0 0.4 3.8 3 1 0 3 3 3 0 Glutaredoxin ERp29_N PF07912.13 KXS15919.1 - 0.0075 16.4 0.7 4.8 7.3 0.0 4.0 3 1 1 4 4 4 1 ERp29, N-terminal domain TraF PF13728.6 KXS15919.1 - 0.019 14.8 0.0 2 8.2 0.0 3.2 4 0 0 4 4 4 0 F plasmid transfer operon protein Thioredoxin_4 PF13462.6 KXS15919.1 - 0.083 13.0 0.8 20 5.3 0.2 3.0 2 0 0 2 2 2 0 Thioredoxin RGS PF00615.19 KXS15920.1 - 0.012 15.8 0.0 0.05 13.9 0.0 1.9 1 1 0 1 1 1 0 Regulator of G protein signaling domain LptF_LptG PF03739.14 KXS15920.1 - 0.22 10.3 2.3 0.39 9.5 2.3 1.4 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG Uma2 PF05685.12 KXS15921.1 - 0.17 11.4 0.0 9.2 5.8 0.0 2.1 2 0 0 2 2 2 0 Putative restriction endonuclease Proteasome PF00227.26 KXS15922.1 - 6.2e-48 162.8 0.1 7.7e-48 162.5 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KXS15922.1 - 9.4e-14 50.8 0.1 1.7e-13 50.0 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature TPR_12 PF13424.6 KXS15923.1 - 0.13 12.6 0.1 0.71 10.2 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 KXS15923.1 - 0.77 9.7 2.8 22 5.1 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat SMN PF06003.12 KXS15924.1 - 4.4e-08 32.7 6.7 6e-08 32.3 6.7 1.1 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) TUDOR PF00567.24 KXS15924.1 - 0.00025 21.1 0.1 0.00052 20.0 0.1 1.5 1 0 0 1 1 1 1 Tudor domain SAWADEE PF16719.5 KXS15924.1 - 0.0094 16.0 0.5 0.021 14.8 0.4 1.7 1 1 0 1 1 1 1 SAWADEE domain BNIP2 PF12496.8 KXS15924.1 - 0.085 13.3 2.2 0.21 12.1 2.2 1.8 1 1 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 DUF4337 PF14235.6 KXS15924.1 - 0.23 11.6 6.1 0.45 10.6 6.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) WRNPLPNID PF15017.6 KXS15924.1 - 0.39 11.6 3.8 6.9 7.6 0.1 2.5 2 0 0 2 2 2 0 Putative WW-binding domain and destruction box zf-CCCH PF00642.24 KXS15926.1 - 2.8e-17 62.2 11.6 1e-08 34.9 2.7 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KXS15926.1 - 2.5e-06 27.2 12.1 0.0044 16.8 0.9 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KXS15926.1 - 2.9e-05 24.0 19.9 0.0013 18.7 4.4 2.3 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_2 PF14608.6 KXS15926.1 - 0.00012 22.4 11.2 0.0039 17.6 0.9 2.4 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger Torus PF16131.5 KXS15926.1 - 1.1 10.0 8.6 0.35 11.6 1.0 2.4 1 1 1 2 2 2 0 Torus domain DUF1279 PF06916.13 KXS15927.1 - 5.8e-13 49.2 0.0 8.2e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) AAA_6 PF12774.7 KXS15928.1 - 7.1e-158 524.8 0.0 4e-156 519.0 0.0 2.7 3 0 0 3 3 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 KXS15928.1 - 7.3e-138 460.0 7.4 7.3e-138 460.0 7.4 3.7 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 KXS15928.1 - 5e-114 380.7 0.0 2.3e-113 378.5 0.0 2.3 3 0 0 3 3 2 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 KXS15928.1 - 1.4e-107 358.9 0.1 6.5e-107 356.7 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 KXS15928.1 - 7.7e-94 312.9 4.8 9e-94 312.7 2.2 2.6 2 0 0 2 2 2 1 ATP-binding dynein motor region AAA_7 PF12775.7 KXS15928.1 - 4.1e-82 274.1 0.2 5.9e-80 267.0 0.0 3.5 4 0 0 4 4 3 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 KXS15928.1 - 5.7e-60 201.9 0.2 1.4e-59 200.6 0.2 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 KXS15928.1 - 1.9e-57 194.8 8.1 4.1e-57 193.8 8.1 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 KXS15928.1 - 2.7e-44 150.0 0.0 9e-42 141.9 0.0 3.2 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 KXS15928.1 - 1e-31 109.7 0.0 3.9e-31 107.8 0.0 2.1 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 KXS15928.1 - 4.4e-18 65.3 0.0 2.9e-17 62.7 0.0 2.5 2 0 0 2 2 1 1 AAA+ lid domain AAA_5 PF07728.14 KXS15928.1 - 1.6e-16 60.5 0.0 1e-05 25.6 0.0 5.7 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA PF00004.29 KXS15928.1 - 7e-07 29.7 0.0 0.17 12.3 0.0 4.1 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KXS15928.1 - 0.00021 21.6 0.0 0.35 11.2 0.0 4.1 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 KXS15928.1 - 0.00087 19.7 0.0 4.2 7.7 0.0 4.9 4 0 0 4 4 4 1 AAA ATPase domain T2SSE PF00437.20 KXS15928.1 - 0.0021 17.2 0.0 0.1 11.6 0.0 3.1 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_30 PF13604.6 KXS15928.1 - 0.0049 16.6 0.1 5.9 6.6 0.2 2.9 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 KXS15928.1 - 0.01 15.3 0.2 0.66 9.3 0.0 3.6 5 0 0 5 5 5 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 KXS15928.1 - 0.026 15.1 0.1 0.71 10.4 0.0 3.6 3 0 0 3 3 2 0 AAA domain CppA_C PF14507.6 KXS15928.1 - 0.055 14.2 0.2 0.49 11.1 0.1 2.7 1 1 1 2 2 1 0 CppA C-terminal EF-hand_7 PF13499.6 KXS15928.1 - 0.059 13.8 0.1 0.4 11.1 0.1 2.6 1 0 0 1 1 1 0 EF-hand domain pair AAA_33 PF13671.6 KXS15928.1 - 0.062 13.5 0.0 23 5.1 0.0 3.0 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KXS15928.1 - 0.11 12.9 0.1 62 4.0 0.0 4.0 3 0 0 3 3 3 0 RNA helicase EF-hand_6 PF13405.6 KXS15928.1 - 0.13 12.2 0.4 1.2 9.2 0.1 2.9 2 0 0 2 2 2 0 EF-hand domain Sugarporin_N PF11471.8 KXS15928.1 - 3.7 7.6 8.5 0.65 10.0 2.1 2.8 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension FliD_N PF02465.18 KXS15928.1 - 6.5 7.5 7.2 58 4.5 0.5 3.7 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DnaG_DnaB_bind PF08278.11 KXS15928.1 - 8.5 7.0 11.1 14 6.3 3.8 3.8 2 0 0 2 2 2 0 DNA primase DnaG DnaB-binding DUF1664 PF07889.12 KXS15928.1 - 9.3 6.3 27.9 0.35 10.9 1.8 5.0 5 0 0 5 5 4 0 Protein of unknown function (DUF1664) zf-RING_4 PF14570.6 KXS15930.1 - 2.7e-22 78.3 11.2 2.7e-22 78.3 11.2 1.6 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 KXS15930.1 - 7.7e-07 28.9 8.1 7.7e-07 28.9 8.1 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.22 KXS15930.1 - 6.8e-05 22.6 1.1 0.044 13.6 0.0 2.9 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Prok-RING_4 PF14447.6 KXS15930.1 - 0.00015 21.6 9.1 0.014 15.3 5.3 2.5 1 1 1 2 2 2 2 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KXS15930.1 - 0.00033 20.9 11.6 0.00033 20.9 11.6 1.9 2 0 0 2 2 2 1 Ring finger domain zf-UDP PF14569.6 KXS15930.1 - 0.00051 20.1 3.3 0.00051 20.1 3.3 2.2 2 0 0 2 2 2 1 Zinc-binding RING-finger zf-C3H1 PF10650.9 KXS15930.1 - 0.004 16.8 0.1 0.017 14.8 0.1 2.1 1 0 0 1 1 1 1 Putative zinc-finger domain Baculo_IE-1 PF05290.11 KXS15930.1 - 0.0064 16.4 3.8 0.012 15.6 3.8 1.3 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) Rtf2 PF04641.12 KXS15930.1 - 0.02 14.3 0.8 0.029 13.7 0.8 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger zf-C3HC4 PF00097.25 KXS15930.1 - 0.32 10.9 14.8 0.042 13.7 10.5 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXS15930.1 - 0.57 10.1 16.5 0.12 12.3 11.1 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXS15930.1 - 2.7 8.1 12.1 2.1 8.5 6.7 2.4 2 0 0 2 2 2 0 RING-type zinc-finger FYVE_2 PF02318.16 KXS15930.1 - 7.1 6.9 9.4 0.098 12.9 1.6 1.8 2 0 0 2 2 2 0 FYVE-type zinc finger DUF2505 PF10698.9 KXS15931.1 - 0.0076 16.4 0.0 0.0099 16.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2505) SOCS_box PF07525.16 KXS15931.1 - 0.099 13.0 1.2 1.9 8.9 0.0 3.3 3 1 0 3 3 3 0 SOCS box AA_permease_2 PF13520.6 KXS15932.1 - 2.1e-58 198.2 36.5 2.8e-58 197.8 36.5 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXS15932.1 - 5.2e-41 140.7 33.5 8.7e-41 140.0 33.5 1.4 1 1 0 1 1 1 1 Amino acid permease AA_permease_C PF13906.6 KXS15932.1 - 4.5e-06 26.6 0.9 4.5e-06 26.6 0.9 3.3 3 0 0 3 3 3 1 C-terminus of AA_permease bZIP_1 PF00170.21 KXS15933.1 - 1.5e-05 25.0 2.5 2.6e-05 24.2 2.5 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KXS15933.1 - 0.0057 16.7 2.1 0.0097 16.0 2.1 1.4 1 0 0 1 1 1 1 Basic region leucine zipper Cep57_CLD_2 PF14197.6 KXS15933.1 - 0.049 13.7 0.2 0.14 12.2 0.1 1.8 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 SH3_9 PF14604.6 KXS15934.1 - 1.8e-05 24.5 0.0 3.1e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXS15934.1 - 0.083 12.5 0.0 0.17 11.5 0.0 1.6 1 1 0 1 1 1 0 SH3 domain Pro_isomerase PF00160.21 KXS15935.1 - 7.6e-50 169.3 0.2 3.1e-49 167.3 0.0 2.0 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 KXS15935.1 - 5.3e-07 30.2 0.3 0.13 13.2 0.0 3.8 3 0 0 3 3 3 3 WD domain, G-beta repeat Nodulin-like PF06813.13 KXS15935.1 - 0.12 11.8 0.1 0.21 11.1 0.1 1.2 1 0 0 1 1 1 0 Nodulin-like CDC45 PF02724.14 KXS15936.1 - 4.3e-149 497.8 0.0 7.7e-149 496.9 0.0 1.4 1 1 0 1 1 1 1 CDC45-like protein BUD22 PF09073.10 KXS15936.1 - 0.074 12.4 15.5 0.11 11.8 15.5 1.1 1 0 0 1 1 1 0 BUD22 TFIIF_alpha PF05793.12 KXS15936.1 - 4.8 5.6 20.7 6.8 5.1 20.7 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) bZIP_1 PF00170.21 KXS15937.1 - 5.8e-07 29.5 10.2 0.00029 20.9 5.7 2.2 1 1 1 2 2 2 2 bZIP transcription factor bZIP_Maf PF03131.17 KXS15937.1 - 0.001 19.5 6.4 0.0016 18.9 6.4 1.2 1 0 0 1 1 1 1 bZIP Maf transcription factor KLRAQ PF10205.9 KXS15937.1 - 0.0046 17.2 2.4 0.0074 16.5 2.4 1.2 1 0 0 1 1 1 1 Predicted coiled-coil domain-containing protein HALZ PF02183.18 KXS15937.1 - 0.039 14.2 0.1 0.067 13.4 0.1 1.3 1 0 0 1 1 1 0 Homeobox associated leucine zipper GBP_C PF02841.14 KXS15937.1 - 0.043 13.2 0.2 0.06 12.7 0.2 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain DMPK_coil PF08826.10 KXS15937.1 - 0.13 12.3 1.7 0.23 11.6 1.7 1.3 1 0 0 1 1 1 0 DMPK coiled coil domain like Glutaredoxin2_C PF04399.13 KXS15937.1 - 0.19 11.6 0.2 0.3 10.9 0.2 1.2 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain MLTR_LBD PF17765.1 KXS15937.1 - 0.22 11.6 4.6 1.4 9.0 3.5 2.1 2 0 0 2 2 2 0 MmyB-like transcription regulator ligand binding domain SHE3 PF17078.5 KXS15937.1 - 0.23 11.1 2.7 0.35 10.6 2.7 1.2 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 bZIP_2 PF07716.15 KXS15937.1 - 0.89 9.7 14.6 2.6 8.2 14.6 1.7 1 1 0 1 1 1 0 Basic region leucine zipper DUF1992 PF09350.10 KXS15938.1 - 0.0026 17.9 0.1 0.022 14.9 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF1992) Rbsn PF11464.8 KXS15938.1 - 0.022 14.5 0.2 0.053 13.3 0.2 1.6 1 0 0 1 1 1 0 Rabenosyn Rab binding domain PAS PF00989.25 KXS15940.1 - 3.7e-11 43.0 0.0 6e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 KXS15940.1 - 2.7e-07 30.8 0.0 4.7e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 PAS domain PAS_8 PF13188.7 KXS15940.1 - 1.8e-05 24.7 0.0 3.3e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 KXS15940.1 - 0.002 18.3 0.0 0.0034 17.6 0.0 1.4 1 0 0 1 1 1 1 PAS fold DnaJ_CXXCXGXG PF00684.19 KXS15941.1 - 0.0033 17.7 2.8 0.0046 17.3 2.8 1.3 1 0 0 1 1 1 1 DnaJ central domain MFS_1 PF07690.16 KXS15942.1 - 3.8e-29 101.7 32.8 5.6e-29 101.2 32.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF444 PF04285.12 KXS15943.1 - 0.097 11.7 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF444) PAM2 PF07145.15 KXS15943.1 - 0.17 11.6 27.0 0.19 11.5 0.5 6.2 5 1 1 6 6 6 0 Ataxin-2 C-terminal region zf-H2C2_2 PF13465.6 KXS15944.1 - 0.00014 22.1 0.4 0.001 19.4 0.1 2.3 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.26 KXS15944.1 - 0.0016 18.8 0.6 0.0016 18.8 0.6 2.6 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXS15944.1 - 0.015 16.1 0.7 0.015 16.1 0.7 2.0 2 0 0 2 2 2 0 C2H2-type zinc finger zf-Di19 PF05605.12 KXS15944.1 - 0.031 14.6 2.3 0.038 14.3 1.3 1.5 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-FPG_IleRS PF06827.14 KXS15944.1 - 0.07 13.0 2.2 0.13 12.2 2.2 1.4 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS zf_C2H2_ZHX PF18387.1 KXS15944.1 - 0.26 10.9 2.5 0.23 11.1 0.3 1.9 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_12 PF18658.1 KXS15944.1 - 0.42 10.2 2.2 0.36 10.4 0.4 1.8 1 1 1 2 2 2 0 Zinc-finger C2H2-type Zn_ribbon_SprT PF17283.2 KXS15944.1 - 0.65 10.0 2.7 3.9 7.4 0.1 2.3 2 0 0 2 2 2 0 SprT-like zinc ribbon domain Zn-ribbon_8 PF09723.10 KXS15944.1 - 1.9 8.7 4.8 2.9 8.1 2.9 2.1 1 1 1 2 2 2 0 Zinc ribbon domain ADH_N PF08240.12 KXS15945.1 - 1.3e-29 102.3 5.7 2.2e-29 101.5 5.7 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXS15945.1 - 6.8e-20 71.4 0.5 1.2e-19 70.5 0.5 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXS15945.1 - 5.6e-05 24.2 0.0 0.0001 23.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KXS15945.1 - 0.00093 18.5 0.6 0.00093 18.5 0.6 2.0 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 KXS15945.1 - 0.0041 16.5 0.2 0.0071 15.7 0.2 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 KXS15945.1 - 0.017 15.0 0.1 0.031 14.2 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 KXS15945.1 - 0.17 11.4 1.3 0.52 9.8 0.4 2.2 2 1 0 3 3 3 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Kinesin PF00225.23 KXS15946.1 - 2.1e-62 211.0 0.0 2.8e-62 210.6 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KXS15946.1 - 1.1e-09 38.4 0.0 1.7e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Microtubule binding AAA_16 PF13191.6 KXS15946.1 - 0.029 14.7 0.2 0.15 12.5 0.2 2.1 1 1 0 1 1 1 0 AAA ATPase domain SAM_PNT PF02198.16 KXS15946.1 - 0.1 12.5 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain DUF87 PF01935.17 KXS15946.1 - 0.15 12.1 0.0 0.36 10.9 0.0 1.6 1 0 0 1 1 1 0 Helicase HerA, central domain Peptidase_M41 PF01434.18 KXS15946.1 - 0.21 11.4 0.6 0.33 10.8 0.1 1.5 2 0 0 2 2 2 0 Peptidase family M41 ABC_membrane PF00664.23 KXS15947.1 - 8.4e-117 389.7 28.3 7.9e-64 216.0 4.3 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KXS15947.1 - 5.1e-69 231.1 0.1 1.2e-34 119.8 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KXS15947.1 - 2.9e-11 43.2 8.0 0.00035 20.1 1.6 4.3 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.12 KXS15947.1 - 3.8e-08 32.8 0.7 0.011 15.0 0.0 3.3 3 0 0 3 3 3 2 Zeta toxin ABC_ATPase PF09818.9 KXS15947.1 - 1.4e-07 30.7 1.3 0.0018 17.1 0.0 3.1 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_16 PF13191.6 KXS15947.1 - 2e-07 31.6 3.5 0.0075 16.7 0.2 3.4 3 1 0 3 3 2 2 AAA ATPase domain AAA_29 PF13555.6 KXS15947.1 - 8.3e-07 28.7 0.9 0.021 14.6 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KXS15947.1 - 8.5e-07 29.0 0.2 0.0085 16.0 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 KXS15947.1 - 2.4e-06 27.9 0.1 0.1 12.9 0.0 3.6 3 1 0 3 3 3 2 AAA domain AAA PF00004.29 KXS15947.1 - 3.1e-06 27.6 0.8 4 7.9 0.0 4.4 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 KXS15947.1 - 9.2e-06 25.5 3.2 0.057 13.1 0.8 3.5 2 2 0 2 2 2 2 AAA domain APS_kinase PF01583.20 KXS15947.1 - 1.6e-05 24.8 0.6 0.57 10.1 0.0 3.4 3 0 0 3 3 3 2 Adenylylsulphate kinase AAA_28 PF13521.6 KXS15947.1 - 5.6e-05 23.4 0.0 0.75 10.0 0.0 3.8 3 1 0 3 3 3 1 AAA domain AAA_15 PF13175.6 KXS15947.1 - 0.00011 22.0 0.0 0.22 11.2 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_5 PF07728.14 KXS15947.1 - 0.00014 21.9 0.6 0.34 10.9 0.0 3.6 4 0 0 4 4 3 1 AAA domain (dynein-related subfamily) G-alpha PF00503.20 KXS15947.1 - 0.00027 20.2 0.0 0.18 11.0 0.0 2.3 2 0 0 2 2 2 2 G-protein alpha subunit AAA_21 PF13304.6 KXS15947.1 - 0.0003 20.7 0.0 0.29 10.9 0.0 3.3 4 0 0 4 4 3 1 AAA domain, putative AbiEii toxin, Type IV TA system Rad17 PF03215.15 KXS15947.1 - 0.00045 20.2 0.1 0.049 13.5 0.1 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_7 PF12775.7 KXS15947.1 - 0.0005 19.6 0.2 0.51 9.8 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_18 PF13238.6 KXS15947.1 - 0.00081 19.9 0.2 0.31 11.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 KXS15947.1 - 0.0016 18.6 0.3 1.8 8.6 0.1 2.7 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_24 PF13479.6 KXS15947.1 - 0.0018 18.1 0.0 2.5 7.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 KXS15947.1 - 0.0029 17.8 0.1 2.5 8.2 0.0 2.7 3 0 0 3 3 2 1 AAA domain DUF815 PF05673.13 KXS15947.1 - 0.004 16.4 0.1 2.4 7.3 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF815) ATP-synt_ab PF00006.25 KXS15947.1 - 0.0054 16.4 0.0 4.1 7.0 0.0 2.7 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain SbcCD_C PF13558.6 KXS15947.1 - 0.011 16.0 8.4 1.4 9.2 0.2 4.6 3 2 0 3 3 2 0 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.6 KXS15947.1 - 0.011 15.3 0.1 1.5 8.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 KXS15947.1 - 0.012 16.1 0.2 6.7 7.1 0.1 2.9 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 KXS15947.1 - 0.013 14.7 0.6 2.4 7.3 0.1 2.3 2 0 0 2 2 2 0 NB-ARC domain MMR_HSR1 PF01926.23 KXS15947.1 - 0.02 15.0 0.3 6.1 7.0 0.0 3.1 3 0 0 3 3 3 0 50S ribosome-binding GTPase PRK PF00485.18 KXS15947.1 - 0.021 14.6 0.0 2.7 7.7 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_19 PF13245.6 KXS15947.1 - 0.031 14.6 0.7 7.8 6.8 0.0 2.9 3 0 0 3 3 2 0 AAA domain RNA_helicase PF00910.22 KXS15947.1 - 0.04 14.3 0.0 4.9 7.6 0.0 2.6 2 0 0 2 2 2 0 RNA helicase IstB_IS21 PF01695.17 KXS15947.1 - 0.056 13.2 0.2 20 4.8 0.0 3.4 3 0 0 3 3 3 0 IstB-like ATP binding protein KAP_NTPase PF07693.14 KXS15947.1 - 0.071 12.3 0.0 6.2 6.0 0.0 2.4 2 0 0 2 2 2 0 KAP family P-loop domain NACHT PF05729.12 KXS15947.1 - 0.094 12.6 0.4 17 5.3 0.0 2.6 2 0 0 2 2 2 0 NACHT domain AAA_PrkA PF08298.11 KXS15947.1 - 0.15 10.9 0.2 2 7.2 0.0 2.4 3 0 0 3 3 3 0 PrkA AAA domain AAA_23 PF13476.6 KXS15947.1 - 0.51 10.8 5.8 5.7 7.4 0.0 3.0 3 0 0 3 3 2 0 AAA domain ANAPC4 PF12896.7 KXS15948.1 - 2.7e-31 108.7 0.0 3.9e-31 108.2 0.0 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 ANAPC4_WD40 PF12894.7 KXS15948.1 - 6.1e-14 52.1 0.0 2e-13 50.5 0.0 2.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 KXS15948.1 - 0.1 13.2 2.0 3 8.4 0.1 3.7 3 0 0 3 3 3 0 PQQ-like domain WD40 PF00400.32 KXS15948.1 - 0.12 13.2 0.1 0.62 11.0 0.1 2.3 2 0 0 2 2 2 0 WD domain, G-beta repeat DUF1624 PF07786.12 KXS15949.1 - 1.1e-08 34.9 0.3 8e-08 32.1 0.1 2.3 3 0 0 3 3 3 1 Protein of unknown function (DUF1624) DUF5009 PF16401.5 KXS15949.1 - 0.00045 19.8 0.1 0.00083 18.9 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5009) Nmad5 PF18757.1 KXS15950.1 - 0.098 12.9 0.1 0.13 12.5 0.1 1.3 1 0 0 1 1 1 0 Nucleotide modification associated domain 5 Ank_2 PF12796.7 KXS15951.1 - 1.1e-19 70.7 0.1 1.5e-09 38.3 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXS15951.1 - 6e-18 64.7 4.1 5e-08 33.1 0.1 2.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KXS15951.1 - 7.8e-17 60.9 2.8 0.0015 18.9 0.0 4.2 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 KXS15951.1 - 9.3e-16 58.0 0.1 0.0015 19.1 0.0 3.9 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXS15951.1 - 5.1e-13 47.9 0.2 0.0013 19.0 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat HutD PF05962.11 KXS15951.1 - 0.1 12.5 0.1 0.11 12.4 0.1 1.1 1 0 0 1 1 1 0 HutD MFS_1 PF07690.16 KXS15953.1 - 8.3e-23 80.9 24.9 1.1e-22 80.5 24.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2236 PF09995.9 KXS15955.1 - 7e-27 95.1 0.0 1.1e-26 94.5 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) MFS_1 PF07690.16 KXS15957.1 - 1.7e-38 132.5 30.8 1.7e-38 132.5 30.8 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily TPR_11 PF13414.6 KXS15958.1 - 4.4e-16 58.3 0.3 8.5e-06 25.4 0.0 3.5 2 2 1 3 3 3 3 TPR repeat TPR_19 PF14559.6 KXS15958.1 - 1.1e-14 54.7 0.8 3.5e-06 27.4 1.3 3.2 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 KXS15958.1 - 7.7e-13 48.9 7.1 8.7e-07 29.5 0.1 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 KXS15958.1 - 8.5e-13 47.4 5.2 2.5e-05 24.0 0.0 4.1 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 KXS15958.1 - 1.2e-09 37.5 2.2 0.00047 19.9 1.2 3.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 KXS15958.1 - 1.9e-09 37.2 0.2 0.026 14.9 0.1 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 KXS15958.1 - 5.3e-08 33.0 5.5 0.00075 19.7 2.0 3.1 1 1 3 4 4 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KXS15958.1 - 6.2e-08 32.8 7.9 0.019 15.8 1.0 4.4 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 KXS15958.1 - 2e-06 27.5 0.5 0.44 10.9 0.6 3.9 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 KXS15958.1 - 2.6e-06 27.5 2.5 0.0043 17.2 1.1 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 KXS15958.1 - 0.00024 20.9 2.2 0.052 13.4 0.9 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_20 PF14561.6 KXS15958.1 - 0.0036 17.6 2.2 0.012 15.9 0.4 2.6 3 2 0 3 3 3 1 Tetratricopeptide repeat TPR_5 PF12688.7 KXS15958.1 - 0.0041 17.4 0.2 0.077 13.2 0.1 2.3 2 0 0 2 2 2 1 Tetratrico peptide repeat TPR_7 PF13176.6 KXS15958.1 - 0.0051 16.7 3.8 0.53 10.4 0.4 3.8 3 1 1 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KXS15958.1 - 0.0074 16.5 0.1 5.1 7.4 0.1 2.4 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.14 KXS15958.1 - 0.013 16.0 7.2 0.21 12.3 0.4 3.4 4 0 0 4 4 2 0 Tetratricopeptide repeat TPR_21 PF09976.9 KXS15958.1 - 0.023 14.4 0.8 2 8.1 0.2 2.5 2 1 0 2 2 2 0 Tetratricopeptide repeat-like domain TPR_6 PF13174.6 KXS15958.1 - 0.44 11.3 2.7 31 5.5 0.2 2.9 3 0 0 3 3 2 0 Tetratricopeptide repeat DHHA1 PF02272.19 KXS15959.1 - 5.2e-07 30.2 0.3 9.2e-07 29.4 0.3 1.5 1 1 0 1 1 1 1 DHHA1 domain DHH PF01368.20 KXS15959.1 - 0.18 12.0 0.0 0.31 11.3 0.0 1.4 1 0 0 1 1 1 0 DHH family DHHC PF01529.20 KXS15960.1 - 1.8e-32 112.3 6.2 2.1e-32 112.0 4.9 1.8 2 0 0 2 2 2 1 DHHC palmitoyltransferase F-box PF00646.33 KXS15963.1 - 0.00029 20.6 8.0 0.00069 19.4 2.1 2.9 3 1 0 3 3 3 1 F-box domain F-box-like PF12937.7 KXS15963.1 - 0.0003 20.6 3.7 0.0003 20.6 3.7 2.5 2 1 0 2 2 2 1 F-box-like PP2 PF14299.6 KXS15963.1 - 0.0056 16.7 0.0 0.0082 16.2 0.0 1.2 1 0 0 1 1 1 1 Phloem protein 2 Abhydrolase_6 PF12697.7 KXS15964.1 - 1.5e-08 35.5 4.9 1.8e-07 32.0 4.9 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXS15964.1 - 1.3e-06 28.3 0.0 0.032 13.9 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Ndr PF03096.14 KXS15964.1 - 0.0033 16.2 0.0 0.0048 15.6 0.0 1.1 1 0 0 1 1 1 1 Ndr family Thioesterase PF00975.20 KXS15964.1 - 0.022 14.9 0.0 2.4 8.2 0.0 2.1 2 0 0 2 2 2 0 Thioesterase domain PX PF00787.24 KXS15967.1 - 1.6e-14 53.9 0.0 3e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 PX domain AA_permease_2 PF13520.6 KXS15968.1 - 1.6e-23 83.3 31.9 2e-23 82.9 31.9 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXS15968.1 - 4.6e-17 61.8 26.6 1.1e-16 60.5 26.6 1.6 1 1 0 1 1 1 1 Amino acid permease CAP_N PF01213.19 KXS15968.1 - 0.095 12.2 2.9 0.16 11.4 2.9 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal EF-hand_7 PF13499.6 KXS15971.1 - 3.7e-13 49.7 13.2 2.7e-11 43.7 4.4 2.9 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KXS15971.1 - 1.5e-09 36.7 10.3 0.00041 19.7 0.4 3.7 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.6 KXS15971.1 - 3.9e-09 35.7 7.2 1.7e-05 24.4 0.4 4.2 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.6 KXS15971.1 - 9.1e-05 22.2 13.9 0.0082 16.0 1.6 4.1 3 1 1 4 4 4 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KXS15971.1 - 0.029 14.7 2.9 0.14 12.4 2.0 2.5 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KXS15971.1 - 0.93 9.5 3.4 23 5.0 0.2 2.5 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand EF-hand_5 PF13202.6 KXS15971.1 - 1.3 8.7 6.5 7.9 6.2 0.3 3.3 3 0 0 3 3 3 0 EF hand CFAP91 PF14738.6 KXS15972.1 - 3.3e-44 150.6 1.6 3.3e-44 150.6 1.6 3.3 3 0 0 3 3 3 1 Cilia- and flagella-associated protein 91 Ion_trans PF00520.31 KXS15973.1 - 0.00013 21.3 4.2 0.00018 20.8 4.2 1.2 1 0 0 1 1 1 1 Ion transport protein RINGv PF12906.7 KXS15974.1 - 0.00045 20.3 1.8 0.0011 19.0 1.8 1.7 1 0 0 1 1 1 1 RING-variant domain DUF2721 PF11026.8 KXS15974.1 - 6.1 6.7 7.5 11 5.9 7.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) zf-C2H2_2 PF12756.7 KXS15975.1 - 1.3e-24 86.4 0.0 1.2e-15 57.7 0.0 3.3 3 0 0 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 KXS15975.1 - 1.5e-05 25.5 12.9 0.0039 17.9 0.5 4.3 4 0 0 4 4 4 2 C2H2-type zinc finger zf-met PF12874.7 KXS15975.1 - 0.00091 19.5 1.3 0.047 14.1 0.1 2.9 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 KXS15975.1 - 0.003 17.9 16.4 0.011 16.1 2.2 4.4 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KXS15975.1 - 0.0071 16.6 2.8 1.9 8.9 0.0 3.2 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 KXS15975.1 - 0.0072 16.9 1.2 25 5.6 0.0 4.1 3 1 1 4 4 4 0 FOXP coiled-coil domain zf-C2H2_3rep PF18868.1 KXS15975.1 - 0.03 15.0 0.1 4.6 7.9 0.0 2.8 2 0 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-C2HC_2 PF13913.6 KXS15975.1 - 0.078 12.9 4.5 3 7.8 0.1 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-H2C2_5 PF13909.6 KXS15975.1 - 2.9 7.7 4.9 3.7 7.4 1.6 2.7 2 0 0 2 2 2 0 C2H2-type zinc-finger domain GAGA PF09237.11 KXS15975.1 - 7.3 6.5 6.4 3.2 7.6 0.7 3.1 4 0 0 4 4 4 0 GAGA factor Pkinase PF00069.25 KXS15976.1 - 7.4e-61 205.8 0.0 8.9e-61 205.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS15976.1 - 8.7e-20 71.1 0.0 1.2e-19 70.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXS15976.1 - 0.0005 19.5 0.0 0.00077 18.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KXS15976.1 - 0.0072 16.3 0.0 0.019 14.9 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family ABC1 PF03109.16 KXS15976.1 - 0.01 16.0 0.0 0.021 15.0 0.0 1.4 1 0 0 1 1 1 0 ABC1 family Choline_kinase PF01633.20 KXS15976.1 - 0.09 12.3 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 KXS15976.1 - 0.17 11.2 0.0 0.28 10.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family IMS PF00817.20 KXS15977.1 - 1.5e-43 148.3 0.0 5.1e-43 146.7 0.0 1.9 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.8 KXS15977.1 - 3.8e-16 59.9 0.6 1.1e-15 58.3 0.2 1.9 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 KXS15977.1 - 0.00024 21.2 0.0 0.0012 19.1 0.0 2.2 2 0 0 2 2 2 1 IMS family HHH motif eIF2A PF08662.11 KXS15978.1 - 4e-33 114.9 0.1 2.2e-31 109.2 0.1 2.8 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 KXS15978.1 - 0.00091 19.5 0.0 0.3 11.4 0.0 4.2 4 2 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KXS15978.1 - 0.32 11.9 2.9 1.7e+02 3.3 0.0 4.8 4 1 1 5 5 5 0 WD domain, G-beta repeat DPM3 PF08285.11 KXS15979.1 - 7.5e-24 83.8 0.0 8.3e-24 83.6 0.0 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF3712 PF12505.8 KXS15980.1 - 9.8e-08 32.3 0.4 3.1e-07 30.7 0.4 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3712) LEA_2 PF03168.13 KXS15980.1 - 9.8e-06 26.1 1.8 0.12 12.9 0.2 3.0 2 0 0 2 2 2 2 Late embryogenesis abundant protein Peptidase_M20 PF01546.28 KXS15981.1 - 5.6e-36 124.2 0.0 8.4e-36 123.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KXS15981.1 - 3e-13 49.7 0.0 4.4e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain AMP-binding PF00501.28 KXS15982.1 - 1.4e-98 330.3 0.0 1.8e-98 329.9 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXS15982.1 - 1.1e-16 61.5 0.1 3.7e-16 59.8 0.1 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain AAA_2 PF07724.14 KXS15982.1 - 0.053 13.6 0.0 0.097 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) NIF3 PF01784.18 KXS15983.1 - 5.1e-60 203.1 0.0 6.4e-60 202.8 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) DDE_3 PF13358.6 KXS15987.1 - 5.4e-10 39.2 0.0 1.2e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_33 PF13592.6 KXS15987.1 - 1e-05 25.1 0.1 1.8e-05 24.3 0.1 1.4 1 0 0 1 1 1 1 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.18 KXS15987.1 - 0.0084 16.3 0.1 0.027 14.7 0.0 1.8 2 0 0 2 2 2 1 Transposase DJ-1_PfpI PF01965.24 KXS15988.1 - 3.3e-10 40.0 0.0 5.7e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 KXS15988.1 - 0.01 15.5 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 0 ThiJ/PfpI family-like BRCT PF00533.26 KXS15988.1 - 0.015 15.6 0.0 0.03 14.7 0.0 1.5 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain ABC_membrane PF00664.23 KXS15989.1 - 1.8e-101 339.4 30.2 8.1e-54 183.1 9.8 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KXS15989.1 - 1.1e-67 226.8 1.8 1.1e-33 116.7 0.0 2.8 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.19 KXS15989.1 - 3.5e-18 65.8 0.0 3.8e-08 33.0 0.0 4.0 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KXS15989.1 - 5.1e-07 30.2 5.3 0.016 15.6 0.2 3.3 2 1 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.6 KXS15989.1 - 1.4e-06 27.9 1.6 0.017 14.9 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 KXS15989.1 - 1.8e-06 28.3 0.9 0.11 12.7 0.0 3.6 2 2 0 2 2 2 2 AAA domain AAA PF00004.29 KXS15989.1 - 1.2e-05 25.7 2.5 0.086 13.3 0.1 4.0 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 KXS15989.1 - 0.00024 20.5 4.1 0.032 13.5 0.0 3.9 4 0 0 4 4 4 1 Zeta toxin RsgA_GTPase PF03193.16 KXS15989.1 - 0.00024 21.0 1.1 0.73 9.7 0.1 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_7 PF12775.7 KXS15989.1 - 0.0005 19.6 0.6 0.28 10.7 0.1 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_30 PF13604.6 KXS15989.1 - 0.00075 19.3 4.0 0.6 9.8 0.8 3.2 2 2 0 2 2 2 2 AAA domain AAA_5 PF07728.14 KXS15989.1 - 0.00087 19.3 0.2 1.3 9.1 0.0 3.0 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) G-alpha PF00503.20 KXS15989.1 - 0.0012 18.1 0.1 0.11 11.7 0.0 2.3 2 0 0 2 2 2 1 G-protein alpha subunit AAA_15 PF13175.6 KXS15989.1 - 0.0015 18.3 2.0 1.3 8.6 0.0 2.8 3 0 0 3 3 3 2 AAA ATPase domain AAA_24 PF13479.6 KXS15989.1 - 0.0018 18.0 0.1 1.2 8.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 KXS15989.1 - 0.0026 17.0 0.2 0.2 10.8 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) ABC_ATPase PF09818.9 KXS15989.1 - 0.0048 15.7 1.5 0.39 9.4 0.3 2.4 2 0 0 2 2 2 1 Predicted ATPase of the ABC class Roc PF08477.13 KXS15989.1 - 0.0071 16.6 0.2 0.45 10.7 0.0 2.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_21 PF13304.6 KXS15989.1 - 0.0075 16.1 0.6 1.4 8.6 0.0 3.2 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system DUF87 PF01935.17 KXS15989.1 - 0.024 14.7 5.5 2 8.4 0.1 3.4 3 0 0 3 3 3 0 Helicase HerA, central domain AAA_33 PF13671.6 KXS15989.1 - 0.033 14.3 0.4 4.3 7.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 KXS15989.1 - 0.042 13.2 0.1 3.1 7.1 0.0 2.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 KXS15989.1 - 0.049 14.2 0.2 21 5.7 0.0 3.1 3 0 0 3 3 2 0 AAA domain Gtr1_RagA PF04670.12 KXS15989.1 - 0.054 12.8 0.2 0.79 9.0 0.0 2.3 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KXS15989.1 - 0.061 13.4 1.1 6.3 6.9 0.1 3.0 2 0 0 2 2 2 0 50S ribosome-binding GTPase SbcCD_C PF13558.6 KXS15989.1 - 0.063 13.5 5.4 3 8.1 0.8 3.9 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 KXS15989.1 - 0.079 13.5 6.8 8.9 6.8 0.0 3.4 3 0 0 3 3 3 0 AAA domain Sigma54_activat PF00158.26 KXS15989.1 - 0.098 12.4 0.0 2.2 8.0 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_25 PF13481.6 KXS15989.1 - 0.11 12.0 3.2 1.9 8.0 0.1 3.1 4 0 0 4 4 3 0 AAA domain Lpp-LpqN PF10738.9 KXS15989.1 - 0.14 11.6 0.2 0.42 10.0 0.1 1.8 2 0 0 2 2 2 0 Probable lipoprotein LpqN RNA_helicase PF00910.22 KXS15989.1 - 0.19 12.1 0.8 14 6.1 0.0 3.3 3 0 0 3 3 2 0 RNA helicase APS_kinase PF01583.20 KXS15989.1 - 0.21 11.5 0.7 5.6 6.8 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase NACHT PF05729.12 KXS15989.1 - 0.24 11.3 0.7 4.6 7.1 0.0 2.3 2 0 0 2 2 2 0 NACHT domain ATP_bind_1 PF03029.17 KXS15989.1 - 0.3 10.8 1.4 4.7 6.9 0.1 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein CAC1F_C PF16885.5 KXS15989.1 - 2.2 7.8 6.4 3.9 7.1 6.4 1.3 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term Ank PF00023.30 KXS15990.1 - 1.2e-07 31.8 0.8 0.11 13.0 0.1 5.1 4 1 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.7 KXS15990.1 - 2.5e-07 31.2 0.0 0.00016 22.2 0.0 3.4 2 1 1 3 3 3 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXS15990.1 - 6.4e-06 26.1 2.4 0.21 12.2 0.0 5.1 6 0 0 6 6 6 1 Ankyrin repeat Ank_4 PF13637.6 KXS15990.1 - 1.3e-05 25.7 0.0 0.46 11.1 0.0 4.9 3 1 1 4 4 4 2 Ankyrin repeats (many copies) KilA-N PF04383.13 KXS15990.1 - 5.5e-05 23.0 0.2 0.00083 19.2 0.2 2.1 1 1 0 1 1 1 1 KilA-N domain Ank_5 PF13857.6 KXS15990.1 - 0.00037 20.7 1.4 1.2 9.5 0.0 4.1 3 1 1 4 4 4 1 Ankyrin repeats (many copies) PBP1_TM PF14812.6 KXS15990.1 - 4.2 7.8 8.2 8.8 6.8 8.2 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Pkinase PF00069.25 KXS15992.1 - 2.5e-73 246.7 0.0 2.7e-73 246.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS15992.1 - 6e-40 137.2 0.0 7.6e-40 136.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXS15992.1 - 8.4e-05 22.6 0.0 0.025 14.5 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 KXS15992.1 - 9.5e-05 22.1 0.0 0.00013 21.7 0.0 1.1 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 KXS15992.1 - 0.00019 20.8 0.3 0.00041 19.8 0.3 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KXS15992.1 - 0.00021 20.4 0.0 0.00025 20.1 0.0 1.3 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KXS15992.1 - 0.00026 20.4 0.0 0.00049 19.5 0.0 1.4 1 1 0 1 1 1 1 Kinase-like FTA2 PF13095.6 KXS15992.1 - 0.00056 19.6 0.0 0.085 12.5 0.0 2.1 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Seadorna_VP7 PF07387.11 KXS15992.1 - 0.013 14.6 0.0 0.019 14.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pox_ser-thr_kin PF05445.11 KXS15992.1 - 0.091 11.7 0.4 0.2 10.6 0.0 1.7 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase PIP49_C PF12260.8 KXS15992.1 - 0.11 12.1 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 MdcG PF10620.9 KXS15992.1 - 0.14 11.9 0.0 0.64 9.8 0.0 1.9 2 0 0 2 2 2 0 Phosphoribosyl-dephospho-CoA transferase MdcG cNMP_binding PF00027.29 KXS15993.1 - 2.1e-20 72.6 0.0 5.5e-06 26.4 0.0 5.0 4 1 0 4 4 4 4 Cyclic nucleotide-binding domain Patatin PF01734.22 KXS15993.1 - 8.4e-17 62.0 0.6 4.2e-14 53.2 0.1 3.2 3 0 0 3 3 3 2 Patatin-like phospholipase PPR_1 PF12854.7 KXS15994.1 - 1.9e-08 33.9 0.0 9.2e-06 25.3 0.0 3.4 3 0 0 3 3 3 1 PPR repeat PPR_2 PF13041.6 KXS15994.1 - 1.5e-05 25.1 0.1 0.017 15.3 0.0 4.0 5 0 0 5 5 5 1 PPR repeat family PPR_3 PF13812.6 KXS15994.1 - 2.6e-05 24.2 0.0 0.26 11.4 0.0 3.7 4 0 0 4 4 4 2 Pentatricopeptide repeat domain PPR PF01535.20 KXS15994.1 - 0.00044 20.3 0.4 0.056 13.7 0.0 3.7 4 0 0 4 4 4 1 PPR repeat SAP PF02037.27 KXS15995.1 - 0.23 11.2 1.8 0.24 11.2 0.2 1.9 2 0 0 2 2 2 0 SAP domain SH3_9 PF14604.6 KXS15996.1 - 7.1e-10 38.6 0.0 8.8e-08 31.9 0.0 3.2 3 0 0 3 3 3 1 Variant SH3 domain SH3_1 PF00018.28 KXS15996.1 - 4e-06 26.3 0.1 1.8e-05 24.3 0.0 2.2 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 KXS15996.1 - 0.00057 19.5 0.0 0.0014 18.3 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain Annexin PF00191.20 KXS15997.1 - 1.4e-57 191.7 0.7 9.7e-15 54.4 0.1 4.1 4 0 0 4 4 4 4 Annexin Acetyltransf_11 PF13720.6 KXS15997.1 - 0.12 12.8 0.6 20 5.7 0.0 3.4 3 0 0 3 3 3 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 adh_short_C2 PF13561.6 KXS15998.1 - 1.4e-44 152.4 1.5 1.6e-44 152.2 1.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXS15998.1 - 6.7e-34 117.1 0.2 8.6e-34 116.7 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXS15998.1 - 0.019 14.9 0.9 0.031 14.2 0.0 1.7 2 0 0 2 2 2 0 KR domain YjeF_N PF03853.15 KXS15998.1 - 0.049 13.5 0.1 0.097 12.6 0.1 1.4 1 0 0 1 1 1 0 YjeF-related protein N-terminus Ank_3 PF13606.6 KXS15999.1 - 1.6e-05 24.9 0.1 0.017 15.6 0.0 3.6 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.7 KXS15999.1 - 0.00039 21.0 0.0 0.023 15.3 0.0 2.7 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 KXS15999.1 - 0.0034 17.8 0.4 0.097 13.2 0.1 2.9 3 0 0 3 3 3 1 Ankyrin repeat DUF3368 PF11848.8 KXS15999.1 - 0.0046 16.7 0.1 1 9.2 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF3368) Ank_4 PF13637.6 KXS15999.1 - 0.022 15.3 0.0 48 4.7 0.0 3.5 3 0 0 3 3 3 0 Ankyrin repeats (many copies) I-set PF07679.16 KXS15999.1 - 0.13 12.3 0.0 5.8 7.1 0.0 2.3 2 0 0 2 2 2 0 Immunoglobulin I-set domain RNase_H PF00075.24 KXS16000.1 - 1e-26 93.9 0.0 9.7e-25 87.4 0.0 2.3 1 1 0 1 1 1 1 RNase H Cauli_VI PF01693.16 KXS16000.1 - 3.5e-15 56.0 1.1 6.4e-15 55.2 1.1 1.5 1 0 0 1 1 1 1 Caulimovirus viroplasmin RVT_3 PF13456.6 KXS16000.1 - 0.0045 16.8 0.0 0.048 13.5 0.0 2.1 2 0 0 2 2 2 1 Reverse transcriptase-like Ank_2 PF12796.7 KXS16001.1 - 6.8e-13 49.0 0.0 3.5e-08 33.9 0.0 2.6 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXS16001.1 - 1.2e-11 44.9 0.2 5.9e-06 26.7 0.0 3.2 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXS16001.1 - 1.9e-10 40.8 1.4 0.0017 18.6 0.0 4.0 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 KXS16001.1 - 6.4e-10 39.0 2.5 0.0084 16.5 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 KXS16001.1 - 2.7e-09 36.5 1.7 0.011 16.2 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeat DX PF01666.17 KXS16002.1 - 9.7 6.7 10.6 8.8 6.9 1.1 2.3 2 0 0 2 2 2 0 DX module Aa_trans PF01490.18 KXS16004.1 - 7e-46 156.7 16.2 9.2e-46 156.3 16.2 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein CRAL_TRIO PF00650.20 KXS16005.1 - 3.2e-11 43.2 0.0 4.6e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain PB1 PF00564.24 KXS16006.1 - 8.5e-07 28.8 0.0 1.8e-06 27.8 0.0 1.5 1 1 0 1 1 1 1 PB1 domain Chitin_synth_1 PF01644.17 KXS16007.1 - 9.4e-62 207.8 0.1 1.5e-61 207.1 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.15 KXS16007.1 - 7.9e-19 67.7 2.6 3e-14 52.6 0.0 2.9 3 0 0 3 3 3 2 Chitin synthase Chitin_synth_1N PF08407.11 KXS16007.1 - 1.8e-17 63.0 0.0 5.2e-17 61.6 0.0 1.8 1 0 0 1 1 1 1 Chitin synthase N-terminal Glyco_trans_2_3 PF13632.6 KXS16007.1 - 9e-12 45.3 0.4 9e-12 45.3 0.4 2.7 2 1 0 2 2 2 1 Glycosyl transferase family group 2 DUF719 PF05334.13 KXS16007.1 - 0.087 13.0 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF719) DUF2207 PF09972.9 KXS16007.1 - 0.59 8.8 3.6 2 7.1 0.0 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) SH3_9 PF14604.6 KXS16008.1 - 1.9e-20 72.4 1.7 4.3e-09 36.1 0.2 2.3 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 KXS16008.1 - 2.2e-12 46.4 1.0 1.1e-05 24.9 0.0 2.5 2 1 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 KXS16008.1 - 1.4e-05 24.7 0.1 0.019 14.6 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain DUF5473 PF17567.2 KXS16008.1 - 0.026 14.8 3.0 0.071 13.4 3.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5473) SnAC PF14619.6 KXS16008.1 - 0.61 10.7 2.2 11 6.8 0.4 2.6 2 0 0 2 2 2 0 Snf2-ATP coupling, chromatin remodelling complex SBP_bac_1 PF01547.25 KXS16008.1 - 2.4 8.0 12.4 0.067 13.1 4.1 2.2 2 1 0 2 2 2 0 Bacterial extracellular solute-binding protein adh_short PF00106.25 KXS16009.1 - 7.9e-33 113.6 0.1 1e-32 113.2 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXS16009.1 - 2.8e-22 79.5 0.2 4e-22 78.9 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXS16009.1 - 3.4e-12 46.6 0.5 8.5e-12 45.3 0.5 1.5 1 1 0 1 1 1 1 KR domain Abhydrolase_6 PF12697.7 KXS16009.1 - 0.0042 17.7 0.2 0.0042 17.7 0.2 1.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family Epimerase PF01370.21 KXS16009.1 - 0.0094 15.4 0.1 0.037 13.5 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.8 KXS16009.1 - 0.014 15.2 0.1 0.032 14.0 0.1 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.6 KXS16009.1 - 0.02 14.8 0.1 0.033 14.1 0.1 1.5 1 0 0 1 1 1 0 NAD(P)H-binding LRR_6 PF13516.6 KXS16011.1 - 9.6e-19 65.8 11.7 0.00033 20.5 0.0 6.9 7 0 0 7 7 7 5 Leucine Rich repeat LRR_4 PF12799.7 KXS16011.1 - 5.2e-07 29.9 3.2 0.011 16.1 0.1 4.0 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) Nucleic_acid_bd PF13820.6 KXS16011.1 - 0.0068 16.3 0.1 0.033 14.0 0.0 1.9 2 0 0 2 2 2 1 Putative nucleic acid-binding region LRR_1 PF00560.33 KXS16011.1 - 0.015 15.7 0.0 1.4e+02 3.7 0.1 4.7 5 0 0 5 5 5 0 Leucine Rich Repeat SpoU_sub_bind PF08032.12 KXS16011.1 - 0.065 13.5 1.7 8.8 6.7 0.0 3.9 3 1 2 5 5 5 0 RNA 2'-O ribose methyltransferase substrate binding LRR_8 PF13855.6 KXS16011.1 - 0.34 10.7 9.4 17 5.2 0.6 4.7 4 2 1 5 5 5 0 Leucine rich repeat Ank_3 PF13606.6 KXS16012.1 - 3e-05 24.1 0.1 0.034 14.7 0.0 4.2 5 0 0 5 5 5 1 Ankyrin repeat Ank PF00023.30 KXS16012.1 - 4.8e-05 23.6 0.3 0.75 10.4 0.0 3.1 3 1 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 KXS16012.1 - 0.00015 22.3 0.0 1.9 9.2 0.0 3.5 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXS16012.1 - 0.00048 20.7 0.1 0.03 14.9 0.0 3.4 4 1 0 4 4 4 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXS16012.1 - 0.021 15.1 0.1 0.22 11.9 0.0 2.7 3 0 0 3 3 3 0 Ankyrin repeats (many copies) bZIP_2 PF07716.15 KXS16012.1 - 0.54 10.4 3.5 0.94 9.6 3.5 1.3 1 0 0 1 1 1 0 Basic region leucine zipper Ank_3 PF13606.6 KXS16014.1 - 0.0019 18.5 0.1 0.0096 16.4 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 KXS16014.1 - 0.002 18.5 0.1 0.03 14.8 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.7 KXS16014.1 - 0.0063 17.1 0.0 0.0096 16.5 0.0 1.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXS16014.1 - 0.021 15.1 0.0 0.068 13.5 0.0 1.7 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXS16014.1 - 0.16 12.6 0.0 0.53 10.9 0.0 1.8 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Phosphorylase PF00343.20 KXS16015.1 - 0 1038.7 0.0 0 1038.5 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase Pkinase PF00069.25 KXS16016.1 - 5.6e-56 189.8 0.0 1.5e-55 188.4 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS16016.1 - 1.7e-40 139.0 0.0 2.8e-40 138.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXS16016.1 - 4.9e-06 25.6 0.0 7.4e-06 25.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KXS16016.1 - 7.3e-05 22.2 0.0 0.00016 21.1 0.0 1.5 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KXS16016.1 - 0.00049 19.8 0.1 0.0011 18.7 0.1 1.6 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 KXS16016.1 - 0.067 12.1 0.3 0.11 11.4 0.3 1.3 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 KXS16016.1 - 0.13 12.2 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF4079 PF13301.6 KXS16017.1 - 0.082 13.1 0.1 0.16 12.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4079) Zip PF02535.22 KXS16018.1 - 6.4e-49 167.0 10.2 8.7e-49 166.5 10.2 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter Trypsin PF00089.26 KXS16019.1 - 1.6e-24 87.0 0.6 2.1e-24 86.5 0.6 1.2 1 0 0 1 1 1 1 Trypsin zf-U1 PF06220.12 KXS16020.1 - 2.6e-16 59.1 3.0 3.6e-16 58.6 3.0 1.2 1 0 0 1 1 1 1 U1 zinc finger adh_short_C2 PF13561.6 KXS16021.1 - 9.3e-42 143.2 1.2 1.1e-41 143.0 1.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXS16021.1 - 4.7e-35 120.8 0.4 6.2e-35 120.4 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXS16021.1 - 6.9e-11 42.4 0.3 9.1e-11 42.0 0.3 1.3 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 KXS16021.1 - 0.00071 18.9 0.0 0.0018 17.6 0.0 1.6 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_10 PF13460.6 KXS16021.1 - 0.031 14.2 0.1 0.044 13.7 0.1 1.4 1 0 0 1 1 1 0 NAD(P)H-binding A_thal_3526 PF09713.10 KXS16021.1 - 0.11 12.7 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 Plant protein 1589 of unknown function (A_thal_3526) DUF4879 PF16219.5 KXS16021.1 - 0.13 12.5 0.1 0.29 11.3 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4879) adh_short PF00106.25 KXS16022.1 - 1.7e-08 34.1 0.5 3.4e-08 33.2 0.5 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXS16022.1 - 3.3e-08 33.4 0.3 1.9e-07 30.9 0.3 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase A_thal_3526 PF09713.10 KXS16022.1 - 0.0079 16.4 0.2 0.015 15.5 0.2 1.3 1 0 0 1 1 1 1 Plant protein 1589 of unknown function (A_thal_3526) THF_DHG_CYH_C PF02882.19 KXS16022.1 - 0.017 14.5 0.0 0.025 13.9 0.0 1.2 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Pkinase PF00069.25 KXS16024.1 - 1.5e-40 139.3 0.0 5.3e-40 137.5 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS16024.1 - 1.5e-17 63.7 0.0 2.2e-17 63.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXS16024.1 - 0.024 13.9 0.0 0.039 13.3 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 KXS16024.1 - 0.057 12.8 0.0 0.091 12.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Cellsynth_D PF03500.13 KXS16025.1 - 0.015 15.2 0.2 0.022 14.6 0.2 1.3 1 0 0 1 1 1 0 Cellulose synthase subunit D Pec_lyase_C PF00544.19 KXS16026.1 - 3.8e-11 43.0 8.4 2.9e-08 33.6 0.5 2.2 2 0 0 2 2 2 2 Pectate lyase Beta_helix PF13229.6 KXS16026.1 - 1.9e-06 27.8 17.0 1.4e-05 25.0 16.2 2.3 1 1 1 2 2 2 2 Right handed beta helix region Phage_attach PF05354.11 KXS16026.1 - 0.088 12.7 0.1 0.33 10.8 0.0 1.9 1 1 0 1 1 1 0 Phage Head-Tail Attachment Glyco_hydro_26 PF02156.15 KXS16028.1 - 2.7e-09 36.9 0.1 1.2e-05 24.9 0.0 2.2 2 0 0 2 2 2 2 Glycosyl hydrolase family 26 EF-hand_5 PF13202.6 KXS16028.1 - 0.082 12.4 0.3 0.18 11.4 0.3 1.5 1 0 0 1 1 1 0 EF hand Acyl-CoA_dh_1 PF00441.24 KXS16029.1 - 7.6e-39 133.3 0.4 1.2e-38 132.6 0.4 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KXS16029.1 - 2.7e-21 75.5 0.3 4.7e-21 74.8 0.3 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.28 KXS16029.1 - 1.6e-20 73.0 0.1 3.7e-20 71.9 0.1 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.16 KXS16029.1 - 6e-12 46.2 0.0 1.2e-11 45.2 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KXS16029.1 - 1.5e-05 25.3 0.0 2.6e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain CK_II_beta PF01214.18 KXS16031.1 - 1.4e-61 207.4 0.0 1.9e-61 207.0 0.0 1.2 1 0 0 1 1 1 1 Casein kinase II regulatory subunit BUD22 PF09073.10 KXS16031.1 - 0.034 13.5 2.5 0.044 13.1 2.5 1.2 1 0 0 1 1 1 0 BUD22 COPI_C PF06957.11 KXS16031.1 - 1.7 7.3 8.4 2.7 6.6 8.4 1.2 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus MFS_1_like PF12832.7 KXS16032.1 - 1.6e-55 188.5 17.7 6.4e-55 186.6 17.7 1.8 1 1 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 KXS16032.1 - 3.2e-20 72.4 40.9 7.7e-17 61.2 25.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily LacY_symp PF01306.19 KXS16032.1 - 3.3e-10 39.3 17.1 1e-06 27.9 7.4 2.2 2 0 0 2 2 2 2 LacY proton/sugar symporter DUF4381 PF14316.6 KXS16032.1 - 0.08 13.2 0.5 0.18 12.0 0.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) NmrA PF05368.13 KXS16033.1 - 5.8e-16 58.7 0.0 7.9e-16 58.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXS16033.1 - 1.2e-11 44.8 0.0 2.1e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KXS16033.1 - 0.00018 21.1 0.0 0.00025 20.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GFO_IDH_MocA PF01408.22 KXS16033.1 - 0.0098 16.7 0.0 0.022 15.6 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.17 KXS16033.1 - 0.016 15.8 0.0 0.037 14.6 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent KR PF08659.10 KXS16033.1 - 0.02 14.8 0.0 0.032 14.1 0.0 1.3 1 0 0 1 1 1 0 KR domain TrkA_N PF02254.18 KXS16033.1 - 0.045 14.0 0.0 0.082 13.2 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Semialdhyde_dh PF01118.24 KXS16033.1 - 0.12 12.8 0.0 0.26 11.7 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain VRR_NUC PF08774.11 KXS16034.1 - 3.9e-19 68.7 0.0 4.4e-19 68.6 0.0 1.1 1 0 0 1 1 1 1 VRR-NUC domain HARE-HTH PF05066.13 KXS16035.1 - 0.008 16.5 0.0 2.4 8.6 0.0 2.6 2 0 0 2 2 2 2 HB1, ASXL, restriction endonuclease HTH domain 7TM_GPCR_Srd PF10317.9 KXS16035.1 - 0.077 12.2 0.1 0.14 11.3 0.1 1.3 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srd Pec_lyase_C PF00544.19 KXS16037.1 - 3.8e-11 43.0 8.4 2.9e-08 33.6 0.5 2.2 2 0 0 2 2 2 2 Pectate lyase Beta_helix PF13229.6 KXS16037.1 - 1.9e-06 27.8 17.0 1.4e-05 25.0 16.2 2.3 1 1 1 2 2 2 2 Right handed beta helix region Phage_attach PF05354.11 KXS16037.1 - 0.088 12.7 0.1 0.33 10.8 0.0 1.9 1 1 0 1 1 1 0 Phage Head-Tail Attachment Alpha-E PF04168.12 KXS16039.1 - 0.028 14.2 0.3 0.049 13.4 0.3 1.3 1 0 0 1 1 1 0 A predicted alpha-helical domain with a conserved ER motif. NYN PF01936.18 KXS16040.1 - 4.7e-06 27.2 0.0 8.7e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 NYN domain CCDC23 PF15674.5 KXS16041.1 - 0.0096 15.9 2.5 0.019 14.9 2.5 1.4 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 23 Fmp27_WPPW PF10359.9 KXS16041.1 - 0.017 14.0 1.2 0.02 13.8 1.2 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain TMCO5 PF14992.6 KXS16041.1 - 0.075 12.6 3.3 0.099 12.2 3.3 1.2 1 0 0 1 1 1 0 TMCO5 family bZIP_1 PF00170.21 KXS16041.1 - 0.2 11.8 17.3 0.57 10.3 17.3 1.8 1 1 0 1 1 1 0 bZIP transcription factor MSP1a PF11670.8 KXS16041.1 - 9.3 5.5 7.8 11 5.2 1.1 2.1 2 0 0 2 2 2 0 Major surface protein 1a (MSP1a) TUG-UBL1 PF11470.8 KXS16045.1 - 1.7e-22 79.4 0.2 3.6e-22 78.4 0.2 1.6 1 0 0 1 1 1 1 TUG ubiquitin-like domain UBX PF00789.20 KXS16045.1 - 2.6e-07 30.7 0.0 0.0039 17.4 0.0 3.5 3 0 0 3 3 3 2 UBX domain Hva1_TUDOR PF11160.8 KXS16046.1 - 1.1e-10 41.6 0.4 1.3e-10 41.3 0.4 1.1 1 0 0 1 1 1 1 Hypervirulence associated proteins TUDOR domain HlyD_3 PF13437.6 KXS16046.1 - 0.04 14.6 0.1 0.046 14.4 0.1 1.1 1 0 0 1 1 1 0 HlyD family secretion protein Trypsin PF00089.26 KXS16047.1 - 2.9e-08 33.8 0.0 3.6e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 Trypsin F-box PF00646.33 KXS16048.1 - 9.1e-09 35.0 2.2 1.8e-08 34.0 0.4 2.5 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KXS16048.1 - 8.3e-07 28.8 0.4 2.2e-06 27.4 0.4 1.8 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 KXS16048.1 - 0.00077 19.3 0.1 0.0015 18.4 0.1 1.5 1 0 0 1 1 1 1 F-box PRANC PF09372.10 KXS16048.1 - 0.24 11.7 0.0 0.49 10.8 0.0 1.5 1 0 0 1 1 1 0 PRANC domain Aldedh PF00171.22 KXS16050.1 - 3.4e-170 566.5 0.4 3.8e-170 566.4 0.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family PYNP_C PF07831.13 KXS16050.1 - 0.015 14.9 0.1 0.04 13.6 0.1 1.7 1 0 0 1 1 1 0 Pyrimidine nucleoside phosphorylase C-terminal domain Aldedh PF00171.22 KXS16051.1 - 1.2e-176 587.8 1.2 1.3e-176 587.6 1.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KXS16051.1 - 0.0024 17.4 0.2 0.17 11.3 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) LuxC PF05893.14 KXS16051.1 - 0.045 12.8 0.8 0.32 10.0 0.8 1.9 1 1 0 1 1 1 0 Acyl-CoA reductase (LuxC) Trypsin PF00089.26 KXS16052.1 - 9.9e-25 87.6 2.3 1.2e-24 87.4 2.3 1.1 1 0 0 1 1 1 1 Trypsin Abhydrolase_3 PF07859.13 KXS16054.1 - 5.9e-40 137.4 0.0 8.2e-40 136.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KXS16054.1 - 8e-12 44.7 0.0 1.2e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 KXS16054.1 - 6.6e-06 25.7 0.2 7.9e-05 22.2 0.0 2.5 2 1 0 2 2 2 1 Prolyl oligopeptidase family BAAT_C PF08840.11 KXS16054.1 - 0.002 18.1 0.0 0.0037 17.2 0.0 1.4 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal COesterase PF00135.28 KXS16054.1 - 0.0022 16.9 0.0 0.071 12.0 0.0 2.1 2 0 0 2 2 2 1 Carboxylesterase family Hydrolase_4 PF12146.8 KXS16054.1 - 0.007 15.7 0.0 0.18 11.0 0.0 2.3 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 KXS16054.1 - 0.015 15.1 0.0 0.024 14.4 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase AXE1 PF05448.12 KXS16054.1 - 0.1 11.3 0.1 0.2 10.3 0.1 1.4 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) Abhydrolase_6 PF12697.7 KXS16054.1 - 4.8 7.7 6.6 0.85 10.2 2.0 2.1 1 1 1 2 2 2 0 Alpha/beta hydrolase family SH3_9 PF14604.6 KXS16055.1 - 2.9e-10 39.8 0.0 8.2e-10 38.4 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXS16055.1 - 9.2e-07 28.4 0.0 1.7e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 SH3 domain Podoplanin PF05808.11 KXS16055.1 - 0.14 12.3 7.1 0.31 11.1 7.1 1.5 1 0 0 1 1 1 0 Podoplanin Sclerostin PF05463.11 KXS16055.1 - 0.16 11.6 0.9 0.31 10.7 0.9 1.4 1 0 0 1 1 1 0 Sclerostin (SOST) Apt1 PF10351.9 KXS16055.1 - 0.49 9.2 5.4 0.72 8.6 5.4 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 KXS16055.1 - 7 5.1 12.6 11 4.4 12.6 1.2 1 0 0 1 1 1 0 Macoilin family MFS_1 PF07690.16 KXS16056.1 - 1.5e-25 89.9 18.7 1.7e-22 79.8 14.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 KXS16057.1 - 6.4e-35 120.7 46.1 4.6e-32 111.3 46.9 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily BTB PF00651.31 KXS16058.1 - 3.5e-10 40.1 0.0 7e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KXS16060.1 - 1.6e-08 34.7 0.0 3.4e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Fungal_trans PF04082.18 KXS16062.1 - 0.0061 15.6 0.0 0.012 14.6 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Calpain_inhib PF00748.19 KXS16062.1 - 7.5 7.1 9.7 1.6 9.2 4.7 2.3 2 1 1 3 3 3 0 Calpain inhibitor MGC-24 PF05283.11 KXS16064.1 - 0.00099 19.6 9.1 0.00099 19.6 9.1 2.4 2 1 0 2 2 2 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin SH3_9 PF14604.6 KXS16064.1 - 0.0042 16.9 0.2 0.011 15.5 0.2 1.7 1 0 0 1 1 1 1 Variant SH3 domain DUF5305 PF17231.2 KXS16064.1 - 0.27 10.6 0.0 0.5 9.7 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5305) SHOCT PF09851.9 KXS16064.1 - 0.36 10.6 1.1 0.6 9.9 1.1 1.3 1 0 0 1 1 1 0 Short C-terminal domain Serine_rich PF08824.10 KXS16066.1 - 0.041 13.9 0.9 0.08 12.9 0.9 1.4 1 0 0 1 1 1 0 Serine rich protein interaction domain Nup54 PF13874.6 KXS16066.1 - 0.051 13.7 4.6 0.11 12.7 4.6 1.4 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 Ala_racemase_N PF01168.20 KXS16069.1 - 3.7e-27 95.4 0.0 4.2e-27 95.2 0.0 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Adaptin_N PF01602.20 KXS16070.1 - 3.2e-125 418.7 1.6 3.8e-125 418.4 1.6 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 KXS16070.1 - 3.8e-40 136.6 0.0 2.1e-39 134.2 0.0 2.3 2 0 0 2 2 2 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.20 KXS16070.1 - 1.8e-17 63.6 0.1 3.8e-17 62.6 0.1 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 KXS16070.1 - 1.5e-07 31.6 0.0 4e-05 23.7 0.0 2.9 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KXS16070.1 - 0.00042 20.3 2.8 0.64 10.4 0.1 4.6 4 0 0 4 4 4 1 HEAT repeat HEAT_2 PF13646.6 KXS16070.1 - 0.0014 19.0 0.3 0.37 11.2 0.1 3.4 3 1 0 3 3 3 1 HEAT repeats RasGEF_N_2 PF14663.6 KXS16070.1 - 0.015 15.7 0.3 1.1 9.7 0.1 3.1 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Proteasom_PSMB PF10508.9 KXS16070.1 - 0.035 12.6 4.2 0.45 9.0 0.4 2.2 2 0 0 2 2 2 0 Proteasome non-ATPase 26S subunit RTP1_C1 PF10363.9 KXS16070.1 - 0.076 13.2 1.0 0.2 11.9 0.3 2.0 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 LRR_4 PF12799.7 KXS16071.1 - 2e-09 37.6 1.7 1.2e-05 25.6 0.3 4.4 1 1 5 6 6 6 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KXS16071.1 - 1.8e-08 34.1 1.4 3.6e-06 26.6 0.1 2.2 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 KXS16071.1 - 3e-05 23.7 3.1 0.0064 16.2 0.2 3.3 1 1 3 4 4 4 3 Leucine rich repeat LRR_6 PF13516.6 KXS16071.1 - 0.25 11.5 2.3 7.3 6.9 0.1 3.4 3 0 0 3 3 3 0 Leucine Rich repeat TPH PF13868.6 KXS16072.1 - 1.6e-53 181.5 125.2 1.6e-53 181.5 125.2 2.1 2 0 0 2 2 2 1 Trichohyalin-plectin-homology domain Sad1_UNC PF07738.13 KXS16073.1 - 4e-23 81.9 0.0 6.8e-23 81.1 0.0 1.4 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Aldedh PF00171.22 KXS16074.1 - 2.2e-112 376.0 0.0 1.7e-110 369.7 0.0 2.0 1 1 0 1 1 1 1 Aldehyde dehydrogenase family FA_hydroxylase PF04116.13 KXS16075.1 - 4.2e-28 98.3 11.1 4.2e-28 98.3 11.1 2.2 2 1 1 3 3 3 1 Fatty acid hydroxylase superfamily QueT PF06177.11 KXS16075.1 - 0.73 10.2 4.1 0.86 10.0 0.0 2.6 3 1 0 3 3 3 0 QueT transporter Sybindin PF04099.12 KXS16076.1 - 1.3e-51 174.3 0.0 1.4e-51 174.2 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 KXS16076.1 - 1.6e-07 31.5 0.0 2.3e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region bZIP_1 PF00170.21 KXS16077.1 - 6.6e-12 45.3 4.9 1.2e-11 44.5 4.9 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KXS16077.1 - 7.7e-09 35.5 8.5 1.1e-08 35.0 7.3 1.8 2 0 0 2 2 2 1 Basic region leucine zipper Aft1_OSA PF11785.8 KXS16077.1 - 0.0017 18.7 1.1 0.0017 18.7 1.1 2.9 3 0 0 3 3 3 1 Aft1 osmotic stress response (OSM) domain bZIP_Maf PF03131.17 KXS16077.1 - 0.02 15.4 1.3 0.02 15.4 1.3 1.8 2 0 0 2 2 2 0 bZIP Maf transcription factor DUF4094 PF13334.6 KXS16077.1 - 0.27 11.7 1.6 0.59 10.6 1.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) AA_permease_2 PF13520.6 KXS16078.1 - 3.8e-52 177.6 50.5 4.7e-52 177.3 50.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXS16078.1 - 3.8e-20 72.0 43.2 5e-20 71.6 43.2 1.0 1 0 0 1 1 1 1 Amino acid permease ING PF12998.7 KXS16079.1 - 1.6e-21 76.8 0.5 2.4e-21 76.2 0.5 1.3 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 KXS16079.1 - 2.5e-06 27.3 6.1 3.9e-06 26.7 6.1 1.3 1 0 0 1 1 1 1 PHD-finger Lebercilin PF15619.6 KXS16079.1 - 0.032 13.9 3.5 0.053 13.2 3.5 1.3 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease ABATE PF07336.11 KXS16079.1 - 0.13 12.9 2.6 12 6.6 0.7 2.3 2 0 0 2 2 2 0 Putative stress-induced transcription regulator FUSC PF04632.12 KXS16079.1 - 0.17 10.4 2.5 0.25 9.8 2.5 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family zf-HC5HC2H PF13771.6 KXS16079.1 - 0.74 10.1 3.7 1.9 8.8 3.7 1.7 1 1 0 1 1 1 0 PHD-like zinc-binding domain Cpn60_TCP1 PF00118.24 KXS16080.1 - 3.2e-164 547.2 2.2 3.7e-164 547.0 2.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family KduI PF04962.12 KXS16080.1 - 0.14 11.5 0.0 0.43 9.8 0.0 1.7 2 0 0 2 2 2 0 KduI/IolB family EMP24_GP25L PF01105.24 KXS16081.1 - 1.1e-50 172.1 1.6 1.3e-50 171.9 1.6 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD SdrD_B PF17210.3 KXS16081.1 - 0.0002 21.5 0.1 0.00033 20.8 0.1 1.3 1 0 0 1 1 1 1 SdrD B-like domain DUF98 PF01947.16 KXS16081.1 - 0.039 13.9 0.7 0.059 13.3 0.7 1.3 1 0 0 1 1 1 0 p-hydroxybenzoic acid synthase CarboxypepD_reg PF13620.6 KXS16081.1 - 0.074 13.3 0.1 0.14 12.4 0.1 1.4 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain BMP2K_C PF15282.6 KXS16081.1 - 0.15 11.9 0.0 0.2 11.5 0.0 1.1 1 0 0 1 1 1 0 BMP-2-inducible protein kinase C-terminus ING PF12998.7 KXS16082.1 - 1.5e-10 41.5 0.1 3e-10 40.6 0.1 1.5 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 KXS16082.1 - 2.7e-05 23.9 7.9 4.5e-05 23.2 7.9 1.4 1 0 0 1 1 1 1 PHD-finger Mu-like_Pro PF10123.9 KXS16082.1 - 0.0051 16.4 1.4 0.007 16.0 1.4 1.1 1 0 0 1 1 1 1 Mu-like prophage I protein zf-C4pol PF14260.6 KXS16082.1 - 0.087 13.3 0.7 0.39 11.2 0.2 2.3 2 0 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta PHD_2 PF13831.6 KXS16082.1 - 0.13 11.8 4.0 0.22 11.1 4.0 1.4 1 0 0 1 1 1 0 PHD-finger zf-HC5HC2H PF13771.6 KXS16082.1 - 0.29 11.4 2.5 0.86 9.9 2.5 1.8 1 1 0 1 1 1 0 PHD-like zinc-binding domain GvpL_GvpF PF06386.11 KXS16082.1 - 0.46 10.4 9.1 0.27 11.1 6.4 1.9 1 1 1 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF FUSC PF04632.12 KXS16082.1 - 1.5 7.3 4.1 1.9 6.9 4.1 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF4192 PF13830.6 KXS16082.1 - 3.4 7.6 9.3 1.5 8.8 6.9 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4192) DUF4598 PF15370.6 KXS16083.1 - 1.3e-11 45.0 14.0 2.2e-10 41.0 14.0 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF4598) Ras PF00071.22 KXS16084.1 - 1.3e-67 226.4 0.1 1.6e-67 226.2 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXS16084.1 - 5.4e-36 123.5 0.0 8.2e-36 122.8 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXS16084.1 - 4.6e-16 58.8 0.1 5.3e-16 58.6 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KXS16084.1 - 8.8e-07 28.7 0.1 2.4e-06 27.2 0.1 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KXS16084.1 - 9e-06 25.8 0.1 0.00021 21.3 0.0 2.2 1 1 1 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KXS16084.1 - 2.3e-05 24.3 0.0 0.22 11.4 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 KXS16084.1 - 3.4e-05 23.3 0.0 4.2e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KXS16084.1 - 0.00074 19.0 0.0 0.00096 18.6 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 KXS16084.1 - 0.0068 15.9 0.0 0.077 12.5 0.0 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_29 PF13555.6 KXS16084.1 - 0.043 13.6 0.1 0.14 11.9 0.1 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 KXS16084.1 - 0.06 13.7 0.0 0.1 13.0 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain MCM PF00493.23 KXS16084.1 - 0.091 11.8 0.0 0.31 10.1 0.0 1.7 2 0 0 2 2 2 0 MCM P-loop domain PduV-EutP PF10662.9 KXS16084.1 - 0.1 12.4 0.0 0.65 9.7 0.0 2.4 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation DUF3963 PF13124.6 KXS16084.1 - 0.11 12.5 0.2 0.22 11.5 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3963) AAA_5 PF07728.14 KXS16084.1 - 0.12 12.3 0.0 0.41 10.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KXS16084.1 - 0.17 12.2 0.0 1 9.6 0.0 2.0 1 1 0 2 2 2 0 AAA domain Pkinase PF00069.25 KXS16085.1 - 1.9e-67 227.4 0.0 2.2e-67 227.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS16085.1 - 4.6e-28 98.2 0.0 6.3e-28 97.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXS16085.1 - 1.2e-06 28.1 0.1 0.00011 21.7 0.1 2.1 1 1 1 2 2 2 2 Kinase-like Haspin_kinase PF12330.8 KXS16085.1 - 0.0069 15.4 0.0 0.023 13.7 0.0 1.8 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KXS16085.1 - 0.039 13.9 0.0 0.059 13.3 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 KXS16085.1 - 0.13 11.8 0.1 0.2 11.2 0.1 1.2 1 0 0 1 1 1 0 RIO1 family AA_permease_2 PF13520.6 KXS16086.1 - 7.6e-59 199.6 42.1 9.1e-59 199.4 42.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXS16086.1 - 7.8e-22 77.5 37.5 9.9e-22 77.2 37.5 1.0 1 0 0 1 1 1 1 Amino acid permease Pkinase PF00069.25 KXS16088.1 - 6.8e-23 81.4 0.0 1e-22 80.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.32 KXS16088.1 - 7.6e-18 64.6 11.2 6.3e-08 33.2 0.4 5.9 5 0 0 5 5 5 4 WD domain, G-beta repeat HEAT PF02985.22 KXS16088.1 - 3.6e-11 42.3 12.7 0.35 11.2 0.1 8.9 9 0 0 9 9 9 4 HEAT repeat HEAT_2 PF13646.6 KXS16088.1 - 5e-07 30.0 10.6 0.071 13.5 2.3 5.0 3 2 1 4 4 4 3 HEAT repeats Pkinase_Tyr PF07714.17 KXS16088.1 - 3.4e-05 23.3 0.0 5.5e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXS16088.1 - 0.00082 18.8 0.0 0.0015 17.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like ANAPC4_WD40 PF12894.7 KXS16088.1 - 0.0068 16.7 0.3 0.41 11.0 0.0 3.6 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Cnd1 PF12717.7 KXS16088.1 - 0.027 14.5 0.1 14 5.7 0.0 3.4 2 2 2 4 4 4 0 non-SMC mitotic condensation complex subunit 1 Ge1_WD40 PF16529.5 KXS16088.1 - 0.039 12.9 0.1 0.078 11.9 0.1 1.4 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Kdo PF06293.14 KXS16088.1 - 0.049 13.0 0.0 0.1 11.9 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXS16088.1 - 0.15 11.9 9.6 0.18 11.7 0.1 3.4 2 2 2 4 4 4 0 Phosphotransferase enzyme family HEAT_EZ PF13513.6 KXS16088.1 - 1.8 9.2 7.4 3.7 8.2 2.4 4.0 4 0 0 4 4 4 0 HEAT-like repeat MFS_1 PF07690.16 KXS16089.1 - 1.3e-37 129.6 32.2 1.3e-37 129.6 32.2 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Ank_2 PF12796.7 KXS16090.1 - 3.7e-21 75.5 0.0 4.7e-05 23.9 0.0 4.6 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXS16090.1 - 1.3e-14 54.1 0.4 3e-08 33.8 0.0 5.2 5 2 2 7 7 7 2 Ankyrin repeats (many copies) Ank PF00023.30 KXS16090.1 - 1.7e-12 47.1 0.0 0.00021 21.6 0.0 5.3 6 0 0 6 6 6 2 Ankyrin repeat Ank_4 PF13637.6 KXS16090.1 - 3e-12 46.8 0.1 0.01 16.4 0.0 6.0 4 2 1 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXS16090.1 - 3.4e-11 42.3 0.1 0.17 12.5 0.0 7.3 7 0 0 7 7 7 1 Ankyrin repeat Ribosomal_L7Ae PF01248.26 KXS16090.1 - 2e-09 37.1 0.0 4.5e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Fungal_trans PF04082.18 KXS16091.1 - 1.1e-13 50.8 0.0 1.2e-13 50.7 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.18 KXS16092.1 - 3.2e-29 101.8 0.1 4.5e-29 101.3 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXS16092.1 - 6.7e-08 32.5 11.3 1.5e-07 31.4 11.3 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.26 KXS16093.1 - 0.0042 17.5 4.6 0.093 13.2 1.4 2.6 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_aberr PF17017.5 KXS16093.1 - 0.0079 16.4 0.2 0.96 9.6 0.0 2.2 2 0 0 2 2 2 2 Aberrant zinc-finger zf-H2C2_2 PF13465.6 KXS16093.1 - 0.077 13.5 6.9 0.6 10.6 0.7 2.9 3 0 0 3 3 3 0 Zinc-finger double domain Peptidase_C37 PF05416.12 KXS16093.1 - 0.099 11.1 0.2 0.13 10.8 0.2 1.2 1 0 0 1 1 1 0 Southampton virus-type processing peptidase Carn_acyltransf PF00755.20 KXS16095.1 - 1.3e-179 598.6 0.0 1.5e-179 598.4 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase HEAT PF02985.22 KXS16096.1 - 3.3e-44 145.1 25.0 0.0018 18.3 0.1 14.9 15 0 0 15 15 15 10 HEAT repeat HEAT_2 PF13646.6 KXS16096.1 - 5.6e-31 106.8 14.6 9e-10 38.8 0.1 8.2 2 2 6 8 8 8 7 HEAT repeats Vac14_Fab1_bd PF12755.7 KXS16096.1 - 2.4e-13 50.5 1.5 0.0011 19.5 0.3 7.4 5 3 4 9 9 9 3 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 KXS16096.1 - 5.9e-11 41.6 1.8 1.1e-07 30.8 0.4 3.4 2 1 1 3 3 3 3 Adaptin N terminal region HEAT_EZ PF13513.6 KXS16096.1 - 8.4e-10 38.9 15.6 0.00028 21.3 0.0 9.1 10 1 1 11 11 11 2 HEAT-like repeat Cnd1 PF12717.7 KXS16096.1 - 1.7e-09 37.9 9.0 0.0099 15.9 0.4 5.7 4 1 2 6 6 6 3 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 KXS16096.1 - 2.6e-07 30.8 2.3 0.14 12.3 0.0 4.5 4 1 0 4 4 4 3 Required for nuclear transport of RNA pol II C-terminus 1 CLASP_N PF12348.8 KXS16096.1 - 0.0002 21.0 3.2 0.12 11.9 0.6 4.2 2 2 2 4 4 4 1 CLASP N terminal IFRD PF05004.13 KXS16096.1 - 0.0025 17.0 1.0 0.026 13.6 0.4 2.8 2 1 0 2 2 2 1 Interferon-related developmental regulator (IFRD) Proteasom_PSMB PF10508.9 KXS16096.1 - 0.0039 15.7 1.8 0.0039 15.7 1.8 2.8 2 1 1 3 3 3 1 Proteasome non-ATPase 26S subunit Arm PF00514.23 KXS16096.1 - 0.028 14.5 2.1 15 5.8 0.0 4.9 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat DNA_alkylation PF08713.11 KXS16096.1 - 0.074 12.8 0.5 9.4 5.9 0.1 2.7 2 1 0 2 2 2 0 DNA alkylation repair enzyme Ribosomal_S3_C PF00189.20 KXS16097.1 - 1.2e-22 80.2 0.4 4.3e-22 78.4 0.3 1.9 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 KXS16097.1 - 1.2e-11 44.3 0.2 2.1e-11 43.5 0.2 1.4 1 0 0 1 1 1 1 KH domain 60KD_IMP PF02096.20 KXS16100.1 - 1.9e-16 60.4 0.0 3.9e-16 59.4 0.0 1.5 1 1 0 1 1 1 1 60Kd inner membrane protein ERAP1_C PF11838.8 KXS16100.1 - 0.043 13.4 0.2 0.065 12.8 0.2 1.2 1 0 0 1 1 1 0 ERAP1-like C-terminal domain FRG PF08867.11 KXS16100.1 - 0.078 13.9 0.1 0.8 10.7 0.0 2.2 2 0 0 2 2 2 0 FRG domain TRM13 PF05206.14 KXS16102.1 - 1.7e-57 194.9 0.0 3.9e-39 134.8 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase TRM13 zf-U11-48K PF05253.12 KXS16102.1 - 7.4e-09 35.3 1.4 1.6e-08 34.2 1.4 1.6 1 0 0 1 1 1 1 U11-48K-like CHHC zinc finger zf-TRM13_CCCH PF11722.8 KXS16102.1 - 0.002 17.9 0.8 0.002 17.9 0.8 1.8 2 0 0 2 2 2 1 CCCH zinc finger in TRM13 protein Methyltransf_32 PF13679.6 KXS16102.1 - 0.0097 15.9 0.5 0.081 12.9 0.0 2.4 3 0 0 3 3 3 1 Methyltransferase domain GIT_SHD PF08518.11 KXS16102.1 - 0.033 13.8 0.1 0.065 12.9 0.1 1.5 1 0 0 1 1 1 0 Spa2 homology domain (SHD) of GIT Rrn6 PF10214.9 KXS16102.1 - 0.25 9.8 10.0 0.11 11.0 5.2 2.0 2 0 0 2 2 2 0 RNA polymerase I-specific transcription-initiation factor CBM_1 PF00734.18 KXS16103.1 - 8.4e-16 57.6 27.9 4.1e-09 36.2 11.5 3.5 3 1 0 3 3 3 2 Fungal cellulose binding domain Band_7 PF01145.25 KXS16104.1 - 1.4e-30 106.6 4.2 2.2e-30 106.0 4.0 1.5 1 1 0 1 1 1 1 SPFH domain / Band 7 family Band_7_C PF16200.5 KXS16104.1 - 2.4e-23 81.9 1.1 4.7e-23 81.0 0.0 2.1 2 0 0 2 2 2 1 C-terminal region of band_7 Band_7_1 PF13421.6 KXS16104.1 - 0.0079 15.9 0.1 0.015 15.1 0.1 1.4 1 0 0 1 1 1 1 SPFH domain-Band 7 family Pox_A11 PF05061.13 KXS16104.1 - 0.042 13.1 0.4 0.063 12.6 0.4 1.4 1 0 0 1 1 1 0 Poxvirus A11 Protein adh_short_C2 PF13561.6 KXS16105.1 - 1.6e-51 175.1 0.6 2.1e-51 174.8 0.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXS16105.1 - 1.3e-42 145.5 0.2 1.7e-42 145.1 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXS16105.1 - 1.1e-08 35.2 0.2 1.7e-08 34.6 0.2 1.2 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 KXS16105.1 - 3.5e-05 24.1 0.2 6.7e-05 23.2 0.2 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain F420_oxidored PF03807.17 KXS16105.1 - 0.00037 21.0 0.6 0.00086 19.9 0.6 1.7 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 KXS16105.1 - 0.0036 17.2 0.2 0.0055 16.6 0.2 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 KXS16105.1 - 0.044 14.2 0.2 0.1 13.0 0.2 1.6 2 0 0 2 2 2 0 Putative NAD(P)-binding ADH_zinc_N PF00107.26 KXS16105.1 - 0.1 12.6 0.7 2.7 8.0 0.7 2.4 1 1 0 1 1 1 0 Zinc-binding dehydrogenase AdoHcyase_NAD PF00670.21 KXS16105.1 - 0.14 12.3 0.8 0.27 11.3 0.5 1.6 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Beta-lactamase PF00144.24 KXS16106.1 - 6.7e-25 88.0 1.2 1.7e-24 86.7 1.2 1.6 1 1 0 1 1 1 1 Beta-lactamase LRR_4 PF12799.7 KXS16107.1 - 6.4e-08 32.8 7.7 0.0034 17.7 1.5 4.1 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXS16107.1 - 6.2e-06 25.9 11.8 5.4e-05 22.9 4.9 3.9 4 1 0 4 4 4 1 Leucine rich repeat LRR_9 PF14580.6 KXS16107.1 - 7.2e-05 22.4 0.5 0.12 11.9 0.4 2.4 2 1 0 2 2 2 2 Leucine-rich repeat Pept_tRNA_hydro PF01195.19 KXS16108.1 - 1.7e-08 34.6 0.0 1.7e-08 34.6 0.0 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase Pept_tRNA_hydro PF01195.19 KXS16109.1 - 4.8e-21 75.4 0.0 6.5e-21 75.0 0.0 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase Band_7 PF01145.25 KXS16110.1 - 0.0016 18.5 0.0 0.0036 17.3 0.0 1.6 1 1 0 1 1 1 1 SPFH domain / Band 7 family PEPcase PF00311.17 KXS16110.1 - 0.092 10.8 0.0 0.12 10.4 0.0 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase F-box-like PF12937.7 KXS16111.1 - 1.3e-06 28.1 0.2 3.6e-06 26.8 0.2 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXS16111.1 - 7.7e-05 22.5 0.1 0.00022 21.0 0.1 1.7 1 0 0 1 1 1 1 F-box domain Pribosyltran PF00156.27 KXS16112.1 - 1.1e-05 25.1 0.2 3.7e-05 23.3 0.0 1.7 2 0 0 2 2 2 1 Phosphoribosyl transferase domain Tim17 PF02466.19 KXS16113.1 - 0.0013 19.0 15.2 0.0015 18.8 1.4 3.0 1 1 2 3 3 3 1 Tim17/Tim22/Tim23/Pmp24 family TraT PF05818.12 KXS16113.1 - 0.0085 15.8 11.7 0.32 10.7 0.2 2.1 1 1 1 2 2 2 2 Enterobacterial TraT complement resistance protein Rick_17kDa_Anti PF05433.15 KXS16113.1 - 0.027 14.3 33.4 0.04 13.8 0.1 2.8 3 0 0 3 3 3 0 Glycine zipper 2TM domain PhoR PF11808.8 KXS16113.1 - 0.042 14.3 0.1 0.042 14.3 0.1 2.3 2 1 0 2 2 2 0 Phosphate regulon sensor protein PhoR Gly-zipper_Omp PF13488.6 KXS16113.1 - 0.2 11.7 37.4 1.6 8.8 21.6 2.6 2 1 0 2 2 2 0 Glycine zipper Gly-zipper_YMGG PF13441.6 KXS16113.1 - 0.89 9.4 40.2 0.94 9.3 6.8 2.8 2 2 0 2 2 2 0 YMGG-like Gly-zipper SH3_9 PF14604.6 KXS16115.1 - 0.00013 21.7 0.0 0.00023 20.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXS16115.1 - 0.0015 18.1 0.0 0.0024 17.4 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KXS16115.1 - 0.14 11.9 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Variant SH3 domain Mito_fiss_reg PF05308.11 KXS16116.1 - 2.5 8.1 4.5 3.1 7.8 4.5 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator PhyH PF05721.13 KXS16117.1 - 1.6e-31 110.2 0.1 1.9e-31 110.0 0.1 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 KXS16117.1 - 0.011 16.1 0.2 1.4 9.4 0.0 2.6 1 1 0 2 2 2 0 Putative 2OG-Fe(II) oxygenase RIX1 PF08167.12 KXS16118.1 - 0.046 13.5 2.3 0.37 10.5 0.0 3.3 4 0 0 4 4 4 0 rRNA processing/ribosome biogenesis Importin_rep_3 PF18806.1 KXS16118.1 - 0.087 12.9 0.0 14 5.8 0.0 2.9 3 0 0 3 3 3 0 Importin 13 repeat GMP_synt_C PF00958.22 KXS16119.1 - 5e-45 151.5 0.1 1e-44 150.5 0.1 1.6 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.28 KXS16119.1 - 1e-37 129.8 0.0 2e-37 128.8 0.0 1.5 2 0 0 2 2 2 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KXS16119.1 - 1.5e-11 44.5 0.0 3.7e-11 43.2 0.0 1.7 1 1 0 1 1 1 1 Peptidase C26 NAD_synthase PF02540.17 KXS16119.1 - 3.9e-09 36.0 0.0 3.6e-06 26.3 0.0 2.3 2 0 0 2 2 2 2 NAD synthase QueC PF06508.13 KXS16119.1 - 0.00032 20.3 0.0 0.02 14.4 0.0 2.2 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 KXS16119.1 - 0.0048 15.7 0.1 0.0086 14.9 0.1 1.4 1 0 0 1 1 1 1 tRNA methyl transferase ThiI PF02568.14 KXS16119.1 - 0.011 15.3 0.0 0.025 14.2 0.0 1.6 2 0 0 2 2 2 0 Thiamine biosynthesis protein (ThiI) PAPS_reduct PF01507.19 KXS16119.1 - 0.12 12.4 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family ATP_bind_3 PF01171.20 KXS16119.1 - 0.19 11.5 0.0 0.37 10.5 0.0 1.5 1 0 0 1 1 1 0 PP-loop family Amidohydro_2 PF04909.14 KXS16120.1 - 1e-56 192.9 0.1 1.2e-56 192.7 0.1 1.0 1 0 0 1 1 1 1 Amidohydrolase GST_N_3 PF13417.6 KXS16121.1 - 6.2e-09 36.1 0.0 1.4e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KXS16121.1 - 6.7e-08 32.7 0.0 1.4e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KXS16121.1 - 0.00011 22.1 0.8 0.0011 19.0 0.1 2.5 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KXS16121.1 - 0.018 15.2 0.0 0.043 14.0 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain HA2 PF04408.23 KXS16122.1 - 2.9e-26 91.8 0.0 7.1e-26 90.6 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KXS16122.1 - 2.4e-21 75.9 0.1 6.1e-21 74.6 0.1 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KXS16122.1 - 1.1e-09 38.6 0.0 2.3e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KXS16122.1 - 2.8e-08 33.7 0.2 7.1e-08 32.4 0.2 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KXS16122.1 - 3.2e-07 30.7 0.2 1.2e-06 28.9 0.1 2.0 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.22 KXS16122.1 - 0.0012 18.5 0.1 0.0041 16.8 0.0 2.0 2 1 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_19 PF13245.6 KXS16122.1 - 0.002 18.5 0.8 0.0037 17.6 0.2 1.8 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KXS16122.1 - 0.01 15.5 0.0 0.024 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Flavi_DEAD PF07652.14 KXS16122.1 - 0.021 14.8 0.1 0.049 13.6 0.1 1.6 1 0 0 1 1 1 0 Flavivirus DEAD domain ABC_tran PF00005.27 KXS16122.1 - 0.042 14.4 0.0 0.33 11.5 0.0 2.5 2 0 0 2 2 2 0 ABC transporter AAA_7 PF12775.7 KXS16122.1 - 0.043 13.3 0.0 0.11 12.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_23 PF13476.6 KXS16122.1 - 0.07 13.6 0.0 0.36 11.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 KXS16122.1 - 0.073 12.1 0.0 0.16 11.0 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein ResIII PF04851.15 KXS16122.1 - 0.086 12.8 0.0 8.7 6.3 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_16 PF13191.6 KXS16122.1 - 0.13 12.6 0.0 0.32 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain Mob1_phocein PF03637.17 KXS16123.1 - 8.2e-29 100.8 0.2 1e-28 100.4 0.2 1.1 1 0 0 1 1 1 1 Mob1/phocein family C2 PF00168.30 KXS16124.1 - 6.3e-13 48.9 0.0 1.1e-12 48.1 0.0 1.4 1 0 0 1 1 1 1 C2 domain Gp_dh_C PF02800.20 KXS16125.1 - 2.2e-66 222.3 0.0 3.2e-66 221.8 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 KXS16125.1 - 5.9e-39 132.5 0.0 1.1e-38 131.6 0.0 1.5 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 KXS16125.1 - 0.0071 16.5 0.0 0.026 14.6 0.0 2.0 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus RasGAP PF00616.19 KXS16126.1 - 1.7e-47 161.9 0.0 1.7e-47 161.9 0.0 2.6 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 KXS16126.1 - 3.1e-44 150.5 1.1 1e-43 148.8 1.1 2.0 1 0 0 1 1 1 1 RasGAP C-terminus CH PF00307.31 KXS16126.1 - 1.5e-14 54.1 0.1 2.1e-13 50.4 0.0 2.9 3 0 0 3 3 3 1 Calponin homology (CH) domain IQ PF00612.27 KXS16126.1 - 7.4e-07 28.4 11.0 0.00089 18.9 0.6 4.1 3 0 0 3 3 3 2 IQ calmodulin-binding motif CAMSAP_CH PF11971.8 KXS16126.1 - 0.036 13.9 0.0 0.33 10.8 0.0 2.3 2 0 0 2 2 2 0 CAMSAP CH domain LEM PF03020.15 KXS16126.1 - 0.11 12.0 1.0 0.88 9.2 0.1 2.5 2 0 0 2 2 2 0 LEM domain CDC24 PF06395.11 KXS16126.1 - 0.13 12.5 0.0 2.1 8.7 0.0 2.8 2 0 0 2 2 2 0 CDC24 Calponin Tom37 PF10568.9 KXS16128.1 - 4.6e-13 49.6 0.1 1.2e-12 48.3 0.0 1.7 2 0 0 2 2 2 1 Outer mitochondrial membrane transport complex protein GST_N_4 PF17172.4 KXS16128.1 - 3.1e-07 31.1 0.0 6.6e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 KXS16128.1 - 0.00075 19.2 0.1 0.002 17.9 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Metallophos PF00149.28 KXS16129.1 - 2.6e-10 41.2 0.0 2.1e-06 28.4 0.0 2.3 2 1 0 2 2 2 2 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KXS16129.1 - 1.7e-06 28.4 0.0 7e-05 23.1 0.0 2.2 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.6 KXS16129.1 - 0.017 14.5 0.0 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily Cellulase PF00150.18 KXS16130.1 - 4.4e-15 55.9 0.1 4.1e-14 52.7 0.0 2.0 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_5_C PF18564.1 KXS16130.1 - 0.022 15.3 0.0 0.069 13.7 0.0 1.9 2 0 0 2 2 2 0 Glycoside hydrolase family 5 C-terminal domain Glyco_hydro_35 PF01301.19 KXS16130.1 - 0.048 13.3 0.0 0.08 12.5 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.15 KXS16130.1 - 0.11 11.8 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Beta-galactosidase 2-Hacid_dh_C PF02826.19 KXS16131.1 - 6.4e-45 152.7 0.0 1.5e-44 151.5 0.0 1.7 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KXS16131.1 - 7.7e-33 113.0 0.1 9.8e-33 112.7 0.1 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KXS16131.1 - 0.00057 20.1 0.1 0.0014 18.8 0.1 1.7 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ACT_4 PF13291.6 KXS16131.1 - 0.026 15.1 0.0 0.058 14.0 0.0 1.6 1 0 0 1 1 1 0 ACT domain ACT PF01842.25 KXS16131.1 - 0.035 13.9 0.0 0.1 12.4 0.0 1.9 1 0 0 1 1 1 0 ACT domain AMP-binding PF00501.28 KXS16134.1 - 9.5e-48 162.8 0.0 1.3e-47 162.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 KXS16134.1 - 9.1e-09 35.1 3.5 1.2e-08 34.8 1.5 2.1 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 KXS16134.1 - 0.014 16.3 0.0 0.034 15.1 0.0 1.7 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain CRAL_TRIO PF00650.20 KXS16135.1 - 3e-10 40.0 0.0 6.4e-10 39.0 0.0 1.6 1 1 0 1 1 1 1 CRAL/TRIO domain AMP-binding PF00501.28 KXS16136.1 - 1.2e-88 297.5 0.0 1.5e-88 297.2 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXS16136.1 - 3.2e-18 66.5 0.2 7e-18 65.4 0.2 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain NAD_binding_10 PF13460.6 KXS16138.1 - 1.6e-17 64.0 0.7 2.3e-17 63.5 0.7 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KXS16138.1 - 1.6e-16 60.6 0.4 2e-16 60.3 0.4 1.1 1 0 0 1 1 1 1 NmrA-like family TrkA_N PF02254.18 KXS16138.1 - 9e-05 22.7 0.1 0.00061 20.0 0.0 2.2 3 0 0 3 3 3 1 TrkA-N domain Epimerase PF01370.21 KXS16138.1 - 0.00025 20.6 0.2 0.00068 19.2 0.2 1.8 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.17 KXS16138.1 - 0.0011 19.5 0.0 0.086 13.4 0.0 3.1 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent GDP_Man_Dehyd PF16363.5 KXS16138.1 - 0.0033 16.9 0.0 0.0075 15.7 0.0 1.5 1 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KXS16138.1 - 0.007 15.5 0.0 0.011 14.9 0.0 1.5 1 0 0 1 1 1 1 RmlD substrate binding domain KR PF08659.10 KXS16138.1 - 0.01 15.8 0.1 0.028 14.3 0.1 1.8 1 1 0 1 1 1 0 KR domain DapB_N PF01113.20 KXS16138.1 - 0.019 15.1 0.2 0.21 11.7 0.0 2.5 3 0 0 3 3 3 0 Dihydrodipicolinate reductase, N-terminus adh_short PF00106.25 KXS16138.1 - 0.031 13.7 0.0 0.055 12.9 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase NAD_binding_4 PF07993.12 KXS16138.1 - 0.036 13.2 0.1 0.055 12.6 0.1 1.2 1 0 0 1 1 1 0 Male sterility protein 3Beta_HSD PF01073.19 KXS16138.1 - 0.043 12.8 0.0 0.065 12.2 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Pkinase PF00069.25 KXS16139.1 - 4.9e-64 216.2 0.0 6.2e-64 215.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS16139.1 - 4.1e-27 95.1 0.0 5.5e-27 94.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KXS16139.1 - 0.00025 20.5 0.1 0.0004 19.8 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXS16139.1 - 0.00054 20.0 0.3 0.0022 17.9 0.3 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXS16139.1 - 0.003 16.4 0.0 0.0055 15.5 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase YrbL-PhoP_reg PF10707.9 KXS16139.1 - 0.0066 16.0 0.1 0.011 15.2 0.1 1.3 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Kinase-like PF14531.6 KXS16139.1 - 0.033 13.5 0.0 0.046 13.0 0.0 1.2 1 0 0 1 1 1 0 Kinase-like RIO1 PF01163.22 KXS16139.1 - 0.18 11.4 0.1 0.3 10.7 0.1 1.2 1 0 0 1 1 1 0 RIO1 family Pkinase PF00069.25 KXS16142.1 - 1.9e-52 178.3 0.0 2.4e-52 177.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS16142.1 - 5.5e-24 84.8 0.0 6.8e-24 84.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXS16142.1 - 1e-06 28.3 0.0 1.9e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KXS16142.1 - 9.2e-06 25.8 0.1 1.3e-05 25.2 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXS16142.1 - 0.0012 17.8 0.0 0.0017 17.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KXS16142.1 - 0.0096 15.3 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Citrate_bind PF16114.5 KXS16143.1 - 3.8e-90 300.1 0.0 6.7e-90 299.3 0.0 1.4 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding Citrate_synt PF00285.21 KXS16143.1 - 9.6e-21 74.2 0.0 9e-18 64.5 0.0 2.7 1 1 1 2 2 2 2 Citrate synthase, C-terminal domain Ligase_CoA PF00549.19 KXS16143.1 - 5.6e-18 65.2 0.2 2.7e-17 63.0 0.1 2.1 2 0 0 2 2 2 1 CoA-ligase CoA_binding PF02629.19 KXS16143.1 - 1.8e-11 44.6 0.0 4.2e-11 43.4 0.0 1.7 1 0 0 1 1 1 1 CoA binding domain ATP-grasp_2 PF08442.10 KXS16143.1 - 3.9e-07 29.8 0.0 8e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.6 KXS16143.1 - 6.5e-06 26.0 0.0 1.7e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain BAR_2 PF10455.9 KXS16144.1 - 0.0012 18.0 0.1 0.0018 17.5 0.1 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking Mis14 PF08641.12 KXS16144.1 - 0.021 15.1 1.8 0.096 13.0 1.8 2.1 1 1 0 1 1 1 0 Kinetochore protein Mis14 like Phage_GPL PF05926.11 KXS16144.1 - 0.077 13.0 0.0 0.22 11.5 0.0 1.7 1 0 0 1 1 1 0 Phage head completion protein (GPL) Peptidase_S8 PF00082.22 KXS16145.1 - 3.1e-25 89.1 15.8 1.1e-24 87.2 15.8 1.7 1 1 0 1 1 1 1 Subtilase family SGL PF08450.12 KXS16146.1 - 1.8e-25 89.9 0.0 5e-25 88.5 0.0 1.7 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Lactonase PF10282.9 KXS16146.1 - 0.00037 19.9 0.0 0.0052 16.1 0.0 1.9 1 1 0 2 2 2 1 Lactonase, 7-bladed beta-propeller Arylesterase PF01731.20 KXS16146.1 - 0.0094 16.1 0.0 0.02 15.1 0.0 1.5 1 0 0 1 1 1 1 Arylesterase NHL PF01436.21 KXS16146.1 - 0.017 15.2 3.0 7 6.9 0.1 3.7 4 0 0 4 4 4 0 NHL repeat Str_synth PF03088.16 KXS16146.1 - 0.029 14.5 0.0 0.062 13.4 0.0 1.5 1 0 0 1 1 1 0 Strictosidine synthase Dor1 PF04124.12 KXS16147.1 - 4.4e-47 160.4 0.0 5.9e-47 160.0 0.0 1.1 1 0 0 1 1 1 1 Dor1-like family Vps54_N PF10475.9 KXS16147.1 - 0.049 12.9 0.0 0.075 12.3 0.0 1.2 1 0 0 1 1 1 0 Vacuolar-sorting protein 54, of GARP complex Mersacidin PF16934.5 KXS16147.1 - 0.15 11.9 0.1 0.48 10.2 0.1 1.9 1 0 0 1 1 1 0 Two-component Enterococcus faecalis cytolysin (EFC) AhpC-TSA PF00578.21 KXS16148.1 - 1.8e-15 56.9 0.0 2.6e-15 56.4 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KXS16148.1 - 0.00019 21.2 0.0 0.00029 20.6 0.0 1.3 1 0 0 1 1 1 1 Redoxin GspH PF12019.8 KXS16148.1 - 0.0069 16.8 0.0 0.014 15.8 0.0 1.6 1 0 0 1 1 1 1 Type II transport protein GspH Methyltransf_23 PF13489.6 KXS16149.1 - 9.8e-15 54.8 0.0 1.4e-14 54.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXS16149.1 - 2.9e-13 50.4 0.0 6.4e-13 49.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXS16149.1 - 3.7e-13 49.9 0.1 3.4e-12 46.9 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXS16149.1 - 8.6e-13 48.8 0.0 3.1e-05 24.6 0.0 2.4 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 KXS16149.1 - 1.3e-10 41.3 0.0 1.8e-05 24.6 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain MTS PF05175.14 KXS16149.1 - 0.00066 19.3 0.0 0.014 14.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase small domain Ubie_methyltran PF01209.18 KXS16149.1 - 0.0076 15.6 0.0 0.28 10.5 0.0 2.2 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_24 PF13578.6 KXS16149.1 - 0.08 14.0 0.0 0.15 13.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PAS_3 PF08447.12 KXS16149.1 - 0.12 12.6 0.1 26 5.2 0.0 2.3 2 0 0 2 2 2 0 PAS fold GST_N PF02798.20 KXS16150.1 - 2.4e-13 50.2 0.0 7.3e-13 48.7 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KXS16150.1 - 1.8e-12 47.5 0.0 3.7e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KXS16150.1 - 2.9e-11 43.5 0.0 6.8e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KXS16150.1 - 0.0002 21.5 0.0 0.00033 20.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KXS16150.1 - 0.0081 16.4 0.0 0.012 15.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KXS16150.1 - 0.07 13.2 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_5 PF18485.1 KXS16150.1 - 0.12 12.7 0.1 0.43 11.0 0.0 2.0 3 0 0 3 3 3 0 Glutathione S-transferase, N-terminal domain ADH_zinc_N_2 PF13602.6 KXS16151.1 - 4.7e-17 63.3 0.0 9.7e-17 62.3 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXS16151.1 - 2.5e-09 37.0 3.3 4.3e-09 36.2 0.4 2.5 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXS16151.1 - 4.9e-09 36.3 1.0 7.3e-09 35.7 0.0 1.8 2 1 0 2 2 2 1 Zinc-binding dehydrogenase DUF2855 PF11017.8 KXS16151.1 - 0.061 13.1 0.0 0.083 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2855) Eno-Rase_NADH_b PF12242.8 KXS16151.1 - 0.12 12.2 0.1 0.26 11.1 0.1 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase A_deaminase PF00962.22 KXS16152.1 - 6.6e-123 410.2 0.0 8.5e-123 409.9 0.0 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase Rft-1 PF04506.13 KXS16153.1 - 3.5e-108 362.6 0.5 4.3e-108 362.3 0.5 1.0 1 0 0 1 1 1 1 Rft protein Polysacc_synt_3 PF13440.6 KXS16153.1 - 2.8e-05 23.5 0.4 2.8e-05 23.5 0.4 2.5 2 1 1 3 3 3 1 Polysaccharide biosynthesis protein DUF2423 PF10338.9 KXS16154.1 - 6.5e-15 55.1 6.0 1.6e-14 53.8 6.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2423) Laps PF10169.9 KXS16154.1 - 0.11 13.1 3.2 0.12 12.9 0.4 2.2 2 0 0 2 2 2 0 Learning-associated protein SH3_9 PF14604.6 KXS16155.1 - 0.011 15.5 0.9 0.019 14.8 0.9 1.3 1 0 0 1 1 1 0 Variant SH3 domain TMEM154 PF15102.6 KXS16155.1 - 0.02 14.8 1.0 0.068 13.1 0.0 2.0 1 1 2 3 3 3 0 TMEM154 protein family SPX PF03105.19 KXS16155.1 - 1.5 8.6 6.4 2.1 8.2 6.4 1.2 1 0 0 1 1 1 0 SPX domain Amidohydro_3 PF07969.11 KXS16156.1 - 2.4e-77 261.4 0.3 4.4e-77 260.6 0.3 1.4 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 KXS16156.1 - 2.9e-15 56.4 0.0 6.2e-12 45.5 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family FUN14 PF04930.15 KXS16156.1 - 4.1e-09 36.7 0.2 4.1e-09 36.7 0.2 2.3 2 0 0 2 2 2 1 FUN14 family DUF4199 PF13858.6 KXS16156.1 - 0.061 13.7 0.2 0.1 13.0 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) EF-hand_1 PF00036.32 KXS16156.1 - 0.28 10.8 1.2 0.45 10.2 0.1 2.0 2 0 0 2 2 2 0 EF hand adh_short_C2 PF13561.6 KXS16158.1 - 1.3e-52 178.7 0.9 1.5e-52 178.5 0.9 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXS16158.1 - 1.9e-36 125.3 2.2 2.5e-36 125.0 2.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXS16158.1 - 0.0082 16.1 0.3 0.018 14.9 0.3 1.6 1 1 0 1 1 1 1 KR domain NmrA PF05368.13 KXS16159.1 - 8e-09 35.4 0.0 1.3e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXS16159.1 - 3.6e-06 27.0 0.0 5.8e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding DapB_N PF01113.20 KXS16159.1 - 0.028 14.6 0.0 0.045 13.9 0.0 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NAD_binding_3 PF03447.16 KXS16159.1 - 0.038 14.6 0.0 0.063 13.9 0.0 1.3 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 KXS16159.1 - 0.076 13.9 0.0 0.15 12.9 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Pigment_DH PF06324.11 KXS16159.1 - 0.16 12.1 0.2 10 6.5 0.0 2.6 2 0 0 2 2 2 0 Pigment-dispersing hormone (PDH) Shikimate_DH PF01488.20 KXS16159.1 - 0.2 11.7 0.0 0.34 11.0 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NmrA PF05368.13 KXS16160.1 - 2.3e-10 40.4 0.0 6.6e-10 38.9 0.0 1.7 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXS16160.1 - 8.1e-10 38.9 0.0 1.2e-09 38.3 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding DapB_N PF01113.20 KXS16160.1 - 3.6e-05 23.9 0.0 5.7e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus GFO_IDH_MocA PF01408.22 KXS16160.1 - 7.9e-05 23.5 0.0 0.00016 22.5 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.24 KXS16160.1 - 0.00057 20.3 0.0 0.0011 19.4 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 KXS16160.1 - 0.01 16.1 0.0 0.017 15.4 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain F420_oxidored PF03807.17 KXS16160.1 - 0.022 15.4 0.1 0.045 14.3 0.1 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Ldh_1_N PF00056.23 KXS16160.1 - 0.14 12.3 0.5 0.31 11.1 0.5 1.7 1 1 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Sel1 PF08238.12 KXS16162.1 - 6.5e-31 106.1 9.0 2.3e-08 34.4 0.4 7.6 7 0 0 7 7 7 6 Sel1 repeat Fungal_trans PF04082.18 KXS16163.1 - 1.9e-07 30.4 0.0 4.5e-07 29.2 0.0 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF2613 PF11021.8 KXS16164.1 - 0.17 12.1 0.2 0.17 12.1 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) adh_short PF00106.25 KXS16165.1 - 1.6e-16 60.4 0.0 3.6e-13 49.4 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXS16165.1 - 2.7e-12 46.7 0.0 3.9e-07 29.9 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase SWIRM-assoc_2 PF16496.5 KXS16165.1 - 0.059 12.2 0.5 0.094 11.6 0.5 1.3 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal KR PF08659.10 KXS16165.1 - 0.12 12.3 0.1 0.31 10.9 0.0 1.7 2 0 0 2 2 2 0 KR domain GDP_Man_Dehyd PF16363.5 KXS16165.1 - 0.16 11.3 0.1 0.35 10.2 0.1 1.5 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase MRP-S26 PF14943.6 KXS16168.1 - 0.006 16.5 11.4 0.021 14.7 0.0 2.8 3 0 0 3 3 3 2 Mitochondrial ribosome subunit S26 DUF4939 PF16297.5 KXS16169.1 - 0.1 12.5 0.1 0.18 11.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) zf-BED PF02892.15 KXS16171.1 - 0.00027 20.9 0.1 0.00051 20.0 0.1 1.4 1 0 0 1 1 1 1 BED zinc finger DUF659 PF04937.15 KXS16171.1 - 0.022 14.6 0.0 0.029 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 KXS16172.1 - 1.9e-14 53.2 0.0 5e-14 51.9 0.0 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4413 PF14372.6 KXS16172.1 - 0.01 16.2 0.2 0.026 14.9 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4413) DUF4175 PF13779.6 KXS16172.1 - 0.043 11.7 0.4 0.06 11.3 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) SH3_9 PF14604.6 KXS16175.1 - 4.5e-08 32.8 0.4 8.3e-08 32.0 0.4 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXS16175.1 - 1.1e-06 28.1 0.0 1.9e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 SH3 domain Protocadherin PF08374.11 KXS16175.1 - 0.00064 19.8 5.3 0.015 15.3 0.0 3.2 2 1 1 3 3 3 1 Protocadherin DAP10 PF07213.11 KXS16175.1 - 0.1 12.6 2.4 0.13 12.3 0.0 2.3 2 0 0 2 2 2 0 DAP10 membrane protein WD40 PF00400.32 KXS16177.1 - 1.3e-36 124.0 31.9 1.5e-07 32.0 0.4 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXS16177.1 - 8.8e-14 51.6 0.2 0.11 12.8 0.0 5.8 4 2 2 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KXS16177.1 - 8.3e-06 25.0 0.0 1.9 7.4 0.0 4.9 3 1 2 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF1921 PF09081.10 KXS16177.1 - 0.049 13.9 0.3 5.5 7.3 0.0 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1921) IKI3 PF04762.12 KXS16177.1 - 0.087 10.8 0.2 0.43 8.5 0.1 2.0 2 0 0 2 2 2 0 IKI3 family SnoaL_2 PF12680.7 KXS16178.1 - 9.6e-09 35.8 0.0 2.1e-06 28.3 0.0 2.3 2 0 0 2 2 2 2 SnoaL-like domain SnoaL PF07366.12 KXS16178.1 - 5e-08 32.8 0.8 0.0023 17.7 0.4 3.4 2 1 0 2 2 2 2 SnoaL-like polyketide cyclase NUDIX PF00293.28 KXS16180.1 - 1.2e-12 48.0 0.0 3.2e-12 46.6 0.0 1.8 2 1 0 2 2 2 1 NUDIX domain Ank_2 PF12796.7 KXS16182.1 - 0.00042 20.8 0.0 0.0066 17.0 0.0 2.5 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXS16182.1 - 0.013 16.0 0.0 0.29 11.8 0.0 2.9 3 0 0 3 3 3 0 Ankyrin repeat Ank_4 PF13637.6 KXS16182.1 - 0.041 14.5 0.0 2.4 8.8 0.0 2.7 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank PF00023.30 KXS16182.1 - 0.046 14.2 0.0 0.89 10.1 0.0 2.7 3 0 0 3 3 3 0 Ankyrin repeat Ank_5 PF13857.6 KXS16182.1 - 0.14 12.5 0.0 0.84 10.0 0.0 2.3 2 0 0 2 2 2 0 Ankyrin repeats (many copies) NAD_binding_6 PF08030.12 KXS16184.1 - 3e-29 102.1 0.0 9.1e-17 61.6 0.0 2.2 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KXS16184.1 - 5.2e-16 58.7 0.0 1.6e-15 57.1 0.0 1.8 1 1 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 KXS16184.1 - 0.00044 20.9 0.0 0.0012 19.4 0.0 1.8 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KXS16184.1 - 0.011 16.0 0.0 0.038 14.3 0.0 1.9 3 0 0 3 3 3 0 Oxidoreductase FAD-binding domain zf-RING_2 PF13639.6 KXS16185.1 - 1.3e-09 38.2 11.2 2.4e-09 37.4 11.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KXS16185.1 - 6.9e-06 25.8 10.7 1.2e-05 25.0 10.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXS16185.1 - 1.1e-05 25.2 7.7 1.8e-05 24.5 7.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXS16185.1 - 3.7e-05 23.6 5.1 6.2e-05 22.9 5.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KXS16185.1 - 0.00026 20.9 11.6 0.0022 18.0 12.3 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 KXS16185.1 - 0.00032 20.9 12.3 0.0011 19.2 12.3 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 KXS16185.1 - 0.00039 20.1 8.9 0.00039 20.1 8.9 1.8 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 KXS16185.1 - 0.00087 19.1 6.1 0.0022 17.8 6.1 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KXS16185.1 - 0.0011 19.0 3.6 0.0019 18.2 3.6 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 KXS16185.1 - 0.0015 18.4 2.4 0.0015 18.4 2.4 2.3 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-Nse PF11789.8 KXS16185.1 - 0.0045 16.8 5.0 0.0082 15.9 5.0 1.3 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit FANCL_C PF11793.8 KXS16185.1 - 0.02 15.1 5.0 0.34 11.1 5.0 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 KXS16185.1 - 0.073 12.7 6.1 0.15 11.7 6.1 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 KXS16185.1 - 0.43 10.4 4.5 0.99 9.3 4.5 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 KXS16185.1 - 1.1 9.5 7.5 2.7 8.2 7.5 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING CTU2 PF10288.9 KXS16185.1 - 1.5 9.1 5.6 14 6.0 0.4 2.2 1 1 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 Amidohydro_2 PF04909.14 KXS16186.1 - 2.1e-14 54.0 0.0 3.2e-14 53.4 0.0 1.3 1 1 0 1 1 1 1 Amidohydrolase MAPEG PF01124.18 KXS16187.1 - 2.4e-16 59.8 1.7 3.6e-16 59.2 1.5 1.4 1 1 0 1 1 1 1 MAPEG family DUF1707 PF08044.11 KXS16187.1 - 0.1 12.7 0.1 0.2 11.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1707) TRAM_LAG1_CLN8 PF03798.16 KXS16188.1 - 0.00021 21.1 19.8 0.00047 20.0 19.8 1.6 1 0 0 1 1 1 1 TLC domain DUF2627 PF11118.8 KXS16188.1 - 0.38 11.4 8.1 12 6.5 0.1 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF2627) An_peroxidase PF03098.15 KXS16190.1 - 4.2e-131 438.1 0.0 8.6e-130 433.8 0.0 2.3 1 1 0 1 1 1 1 Animal haem peroxidase NAD_binding_6 PF08030.12 KXS16190.1 - 1.6e-25 90.0 0.0 2.9e-25 89.2 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KXS16190.1 - 8.8e-17 61.2 0.0 2.3e-16 59.8 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 KXS16190.1 - 8.7e-13 48.5 18.4 2e-12 47.3 16.4 2.4 2 0 0 2 2 2 1 Ferric reductase like transmembrane component EF-hand_7 PF13499.6 KXS16190.1 - 4.1e-08 33.6 2.0 0.00013 22.3 0.1 3.2 1 1 3 4 4 4 2 EF-hand domain pair EF-hand_1 PF00036.32 KXS16190.1 - 1e-06 27.9 4.0 0.03 13.9 0.1 3.6 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.6 KXS16190.1 - 1.5e-06 27.7 3.6 0.0033 17.2 0.2 3.6 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.6 KXS16190.1 - 4.5e-06 26.4 0.6 0.22 11.4 0.0 3.6 3 0 0 3 3 3 2 EF-hand domain pair NAD_binding_1 PF00175.21 KXS16190.1 - 0.056 14.1 0.1 0.18 12.4 0.0 1.9 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain EF-hand_5 PF13202.6 KXS16190.1 - 0.096 12.2 0.4 3.2 7.4 0.1 2.7 2 0 0 2 2 2 0 EF hand DuoxA PF10204.9 KXS16191.1 - 4.9e-44 150.4 3.5 9.1e-44 149.5 3.5 1.3 1 0 0 1 1 1 1 Dual oxidase maturation factor MscL PF01741.18 KXS16192.1 - 4.1e-17 62.6 0.0 5.4e-17 62.2 0.0 1.1 1 0 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL Aldo_ket_red PF00248.21 KXS16193.1 - 1.3e-47 162.4 0.0 1.6e-47 162.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Peptidase_C39_2 PF13529.6 KXS16193.1 - 0.027 15.0 0.0 8.9 6.9 0.0 2.2 2 0 0 2 2 2 0 Peptidase_C39 like family BMFP PF04380.13 KXS16193.1 - 0.056 13.9 0.0 11 6.6 0.0 2.4 2 0 0 2 2 2 0 Membrane fusogenic activity Rnk_N PF14760.6 KXS16193.1 - 0.07 13.6 1.1 14 6.2 0.0 3.0 3 0 0 3 3 3 0 Rnk N-terminus Sacchrp_dh_NADP PF03435.18 KXS16195.1 - 1.4e-13 51.3 1.4 1.5e-12 47.9 1.4 2.3 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain adh_short PF00106.25 KXS16195.1 - 0.00017 21.1 0.4 0.0003 20.3 0.4 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Shikimate_DH PF01488.20 KXS16195.1 - 0.00086 19.4 0.0 0.0016 18.6 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Semialdhyde_dh PF01118.24 KXS16195.1 - 0.0011 19.4 0.3 0.003 18.0 0.1 1.8 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.10 KXS16195.1 - 0.0025 17.7 0.3 0.0069 16.3 0.3 1.7 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KXS16195.1 - 0.0039 17.1 0.5 0.0063 16.4 0.5 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KXS16195.1 - 0.0066 15.9 0.1 0.013 14.9 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXS16195.1 - 0.025 13.6 0.0 0.037 13.0 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 KXS16195.1 - 0.029 13.9 0.3 0.096 12.2 0.5 1.7 2 0 0 2 2 2 0 NmrA-like family AMP-binding PF00501.28 KXS16196.1 - 3.7e-94 315.7 0.2 5.2e-94 315.2 0.2 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXS16196.1 - 8.3e-15 55.5 0.2 2e-14 54.3 0.2 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Aldo_ket_red PF00248.21 KXS16197.1 - 9.4e-42 143.2 0.0 2.4e-40 138.6 0.0 2.1 1 1 0 1 1 1 1 Aldo/keto reductase family DUF1656 PF07869.12 KXS16197.1 - 0.46 10.5 2.9 0.39 10.7 0.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1656) BCDHK_Adom3 PF10436.9 KXS16198.1 - 9.1e-36 123.1 0.0 1.3e-35 122.6 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KXS16198.1 - 2.3e-11 44.2 0.0 3.9e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase AF-4 PF05110.13 KXS16199.1 - 4.9e-05 21.7 15.9 6.3e-05 21.3 15.9 1.1 1 0 0 1 1 1 1 AF-4 proto-oncoprotein Dicty_REP PF05086.12 KXS16199.1 - 0.44 8.5 6.3 0.6 8.0 6.3 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DivIC PF04977.15 KXS16199.1 - 1.7 8.4 7.4 5 7.0 6.8 2.1 1 1 0 1 1 1 0 Septum formation initiator zf-CCHC PF00098.23 KXS16201.1 - 6.8e-05 22.8 1.3 6.8e-05 22.8 1.3 2.1 2 0 0 2 2 2 1 Zinc knuckle zf-RING_2 PF13639.6 KXS16202.1 - 2.6e-12 46.9 3.0 4.3e-12 46.2 3.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KXS16202.1 - 1.7e-09 37.4 2.5 2.7e-09 36.7 2.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXS16202.1 - 3.4e-09 36.6 3.0 9e-09 35.2 0.3 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_11 PF17123.5 KXS16202.1 - 3.5e-08 33.0 0.6 3.5e-08 33.0 0.6 1.9 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 KXS16202.1 - 1.1e-07 31.6 0.3 1.8e-07 30.9 0.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KXS16202.1 - 6.9e-07 29.5 3.0 1.6e-06 28.3 3.0 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KXS16202.1 - 1e-06 28.6 0.3 1.8e-06 27.8 0.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KXS16202.1 - 1.1e-06 28.3 0.8 1.9e-06 27.6 0.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KXS16202.1 - 2.7e-05 24.2 1.5 5.5e-05 23.2 1.5 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KXS16202.1 - 0.00047 20.0 2.6 0.0027 17.5 2.7 2.0 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KXS16202.1 - 0.0026 17.8 2.2 0.011 15.7 2.2 1.9 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 KXS16202.1 - 0.0087 15.7 4.0 0.018 14.7 4.0 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3H2C3 PF17122.5 KXS16202.1 - 0.16 12.0 4.1 0.22 11.6 0.8 2.4 2 0 0 2 2 2 0 Zinc-finger Ank_2 PF12796.7 KXS16204.1 - 1.2e-05 25.8 1.0 0.33 11.6 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Serglycin PF04360.12 KXS16204.1 - 6.7 6.7 9.1 7.6 6.5 1.9 2.3 2 0 0 2 2 2 0 Serglycin Cation_efflux PF01545.21 KXS16207.1 - 1.5e-54 184.8 4.6 1.9e-54 184.5 4.6 1.1 1 0 0 1 1 1 1 Cation efflux family DUF4407 PF14362.6 KXS16207.1 - 0.086 12.2 0.5 0.45 9.8 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) TctB PF07331.11 KXS16207.1 - 0.35 11.1 11.7 13 6.0 7.6 3.7 2 1 1 3 3 3 0 Tripartite tricarboxylate transporter TctB family DUF1282 PF06930.12 KXS16207.1 - 0.71 9.6 9.5 0.049 13.4 4.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1282) Zip PF02535.22 KXS16207.1 - 4.1 6.5 17.0 1.9 7.7 12.7 2.2 1 1 1 3 3 3 0 ZIP Zinc transporter DUF1656 PF07869.12 KXS16207.1 - 6.1 6.9 9.9 0.24 11.4 0.3 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1656) NAD_binding_10 PF13460.6 KXS16208.1 - 0.0012 18.7 0.5 0.0032 17.4 0.0 1.9 2 0 0 2 2 2 1 NAD(P)H-binding F420_oxidored PF03807.17 KXS16208.1 - 0.046 14.3 0.4 0.17 12.5 0.0 2.0 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent VIT1 PF01988.19 KXS16209.1 - 4.6e-53 180.3 3.9 5.8e-53 179.9 3.9 1.1 1 0 0 1 1 1 1 VIT family DUF4498 PF14926.6 KXS16210.1 - 1.4e-64 217.8 0.0 1.6e-64 217.6 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4498) GSIII_N PF12437.8 KXS16211.1 - 1.1e-62 210.4 0.0 2.3e-62 209.4 0.0 1.5 1 0 0 1 1 1 1 Glutamine synthetase type III N terminal Gln-synt_C-ter PF18318.1 KXS16211.1 - 2.3e-40 137.1 1.3 4.8e-40 136.1 1.3 1.6 1 0 0 1 1 1 1 Glutamine synthetase C-terminal domain Gln-synt_C PF00120.24 KXS16211.1 - 2.6e-16 59.6 0.0 8.3e-16 57.9 0.0 1.8 2 0 0 2 2 2 1 Glutamine synthetase, catalytic domain SesA PF17107.5 KXS16211.1 - 0.3 11.3 1.9 12 6.2 0.5 2.5 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF3419 PF11899.8 KXS16212.1 - 1.9e-141 471.8 0.0 2.7e-141 471.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_25 PF13649.6 KXS16212.1 - 7.5e-07 29.8 0.0 2.7e-06 28.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXS16212.1 - 1.4e-05 25.0 0.0 3.2e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXS16212.1 - 8.3e-05 22.0 0.0 0.00021 20.7 0.0 1.6 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KXS16212.1 - 0.00022 21.9 0.0 0.00057 20.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXS16212.1 - 0.007 16.2 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KXS16212.1 - 0.0075 16.0 0.0 0.032 14.0 0.0 1.9 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_2 PF00891.18 KXS16212.1 - 0.032 13.5 0.0 0.063 12.6 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase domain Mpv17_PMP22 PF04117.12 KXS16213.1 - 4.6e-10 39.6 0.1 7.7e-10 38.9 0.1 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family RraA-like PF03737.15 KXS16214.1 - 8e-21 74.8 0.9 1.1e-20 74.3 0.9 1.2 1 0 0 1 1 1 1 Aldolase/RraA RPN13_C PF16550.5 KXS16214.1 - 0.04 14.1 0.1 0.91 9.7 0.0 2.1 2 0 0 2 2 2 0 UCH-binding domain PRA-PH PF01503.17 KXS16214.1 - 0.15 12.5 0.0 0.88 10.0 0.0 2.1 2 0 0 2 2 2 0 Phosphoribosyl-ATP pyrophosphohydrolase Chromo PF00385.24 KXS16215.1 - 4.4e-13 48.9 1.3 1.3e-12 47.5 0.8 2.1 3 0 0 3 3 3 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.19 KXS16215.1 - 0.00022 21.3 0.0 0.0048 17.0 0.0 2.6 2 0 0 2 2 2 1 Chromo shadow domain UPF0492 PF15744.5 KXS16215.1 - 0.0088 15.3 1.1 0.013 14.8 1.1 1.3 1 0 0 1 1 1 1 Uncharacterized protein family UPF0492 CDC27 PF09507.10 KXS16215.1 - 0.17 11.2 11.6 0.21 10.9 11.6 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Reeler PF02014.16 KXS16217.1 - 7.7e-05 23.4 0.3 0.00011 22.9 0.3 1.3 1 0 0 1 1 1 1 Reeler domain Reeler PF02014.16 KXS16218.1 - 0.0034 18.1 0.0 0.0046 17.7 0.0 1.2 1 0 0 1 1 1 1 Reeler domain F-box-like PF12937.7 KXS16220.1 - 7.3e-05 22.6 0.1 0.00019 21.3 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXS16220.1 - 0.094 12.6 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 F-box domain DUF5421 PF17458.2 KXS16221.1 - 0.15 11.5 0.8 0.28 10.5 0.8 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5421) Herpes_UL25 PF01499.16 KXS16222.1 - 0.055 12.0 4.6 0.026 13.1 1.1 1.9 1 1 1 2 2 2 0 Herpesvirus UL25 family CCDC154 PF15450.6 KXS16222.1 - 0.073 11.6 0.1 0.073 11.6 0.1 1.8 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 154 AIP3 PF03915.13 KXS16222.1 - 0.11 11.6 0.4 0.17 11.0 0.4 1.2 1 0 0 1 1 1 0 Actin interacting protein 3 SKA2 PF16740.5 KXS16222.1 - 0.11 12.2 1.2 3.6 7.4 0.1 2.3 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 Golgin_A5 PF09787.9 KXS16222.1 - 0.12 11.8 1.2 3.8 6.9 0.3 2.2 2 0 0 2 2 2 0 Golgin subfamily A member 5 Dynactin_p22 PF07426.11 KXS16222.1 - 0.16 11.8 2.3 3.9 7.3 0.5 2.4 2 1 0 2 2 2 0 Dynactin subunit p22 Spc7 PF08317.11 KXS16222.1 - 1.8 7.4 4.1 2.7 6.8 1.4 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 KXS16222.1 - 5.8 7.0 8.8 4.4 7.4 0.4 2.9 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein MFS_1 PF07690.16 KXS16224.1 - 6.8e-26 91.0 57.7 2.4e-22 79.4 37.2 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KXS16224.1 - 0.082 11.4 19.0 0.2 10.2 5.7 2.6 1 1 1 2 2 2 0 MFS/sugar transport protein UPF0220 PF05255.11 KXS16225.1 - 1.6e-39 135.1 0.4 2.1e-39 134.8 0.4 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) Sel1 PF08238.12 KXS16226.1 - 2e-37 126.8 32.8 3.2e-08 34.0 0.1 9.5 10 0 0 10 10 10 7 Sel1 repeat PCP_red PF08369.10 KXS16226.1 - 0.21 11.8 1.6 0.48 10.7 0.7 2.1 2 0 0 2 2 2 0 Proto-chlorophyllide reductase 57 kD subunit SWIRM PF04433.17 KXS16227.1 - 0.00052 20.3 0.0 0.00091 19.5 0.0 1.4 1 0 0 1 1 1 1 SWIRM domain MFS_1 PF07690.16 KXS16228.1 - 7.6e-26 90.9 47.5 9.6e-17 60.9 26.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KXS16228.1 - 0.0086 14.7 22.1 0.022 13.3 6.0 2.8 2 1 0 2 2 2 2 MFS/sugar transport protein Nodulin-like PF06813.13 KXS16228.1 - 0.25 10.8 18.5 0.27 10.7 2.4 2.4 2 0 0 2 2 2 0 Nodulin-like F-box-like PF12937.7 KXS16229.1 - 4.4e-06 26.5 2.1 5.8e-06 26.1 0.7 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KXS16229.1 - 0.054 13.4 0.3 0.14 12.1 0.3 1.6 1 0 0 1 1 1 0 F-box domain Mpp10 PF04006.12 KXS16230.1 - 3e-104 349.7 43.4 4e-104 349.3 43.4 1.0 1 0 0 1 1 1 1 Mpp10 protein F-box-like PF12937.7 KXS16231.1 - 5.3e-05 23.0 0.1 0.00013 21.8 0.1 1.7 1 0 0 1 1 1 1 F-box-like MFS_1 PF07690.16 KXS16232.1 - 2.1e-50 171.7 32.9 2.1e-50 171.7 32.9 2.5 1 1 2 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.24 KXS16232.1 - 2.3e-15 56.4 27.1 1.9e-12 46.8 11.3 3.8 3 2 1 4 4 4 3 Sugar (and other) transporter MFS_3 PF05977.13 KXS16232.1 - 5.3e-06 25.1 1.7 5.3e-06 25.1 1.7 1.6 1 1 1 2 2 2 1 Transmembrane secretion effector MFS_2 PF13347.6 KXS16232.1 - 0.0011 17.7 27.0 0.0028 16.3 5.8 4.0 2 1 2 4 4 4 3 MFS/sugar transport protein OATP PF03137.20 KXS16232.1 - 0.029 12.7 9.0 0.014 13.7 0.8 3.4 4 1 0 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family Transgly_assoc PF04226.13 KXS16232.1 - 0.082 13.2 14.4 0.24 11.7 6.5 3.6 3 0 0 3 3 3 0 Transglycosylase associated protein MFS_1_like PF12832.7 KXS16232.1 - 0.95 8.2 18.5 0.0074 15.2 6.0 2.7 2 1 0 3 3 3 0 MFS_1 like family RseC_MucC PF04246.12 KXS16232.1 - 9.1 6.2 6.2 1.1 9.2 0.3 2.5 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Flavin_Reduct PF01613.18 KXS16233.1 - 2.4e-05 24.4 0.1 3e-05 24.1 0.1 1.2 1 0 0 1 1 1 1 Flavin reductase like domain TRAM_LAG1_CLN8 PF03798.16 KXS16234.1 - 4.4e-15 55.9 4.5 4.6e-15 55.9 4.5 1.0 1 0 0 1 1 1 1 TLC domain zf-C3HC4_3 PF13920.6 KXS16235.1 - 0.00016 21.4 6.5 0.00019 21.2 6.5 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) M60-like_N PF17291.2 KXS16235.1 - 0.073 13.0 0.0 0.081 12.8 0.0 1.1 1 0 0 1 1 1 0 N-terminal domain of M60-like peptidases ADD_DNMT3 PF17980.1 KXS16235.1 - 0.074 13.1 7.0 0.12 12.4 2.3 2.1 2 0 0 2 2 2 0 Cysteine rich ADD domain in DNMT3 Zn-ribbon_8 PF09723.10 KXS16235.1 - 0.23 11.6 0.2 0.23 11.6 0.2 2.9 2 1 1 3 3 3 0 Zinc ribbon domain zf-CHY PF05495.12 KXS16235.1 - 0.32 11.5 7.5 0.99 9.9 7.5 1.7 1 1 0 1 1 1 0 CHY zinc finger Fer4_6 PF12837.7 KXS16235.1 - 1.8 8.8 7.3 5.6 7.2 0.1 3.1 3 0 0 3 3 3 0 4Fe-4S binding domain zf-C2H2_3 PF13878.6 KXS16235.1 - 6.7 6.6 8.3 7.2 6.5 0.1 2.5 1 1 1 2 2 2 0 zinc-finger of acetyl-transferase ESCO MFS_1 PF07690.16 KXS16236.1 - 1.1e-42 146.3 50.5 7.7e-42 143.5 49.3 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KXS16236.1 - 4.1e-23 81.7 24.2 5.3e-23 81.3 24.2 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KXS16236.1 - 1.3e-10 40.7 7.7 1.3e-10 40.7 7.7 3.4 3 1 1 4 4 4 1 Sugar (and other) transporter Sdh_cyt PF01127.22 KXS16237.1 - 1.6e-13 50.7 1.6 2.6e-13 50.1 1.4 1.4 2 0 0 2 2 2 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Sdh_cyt PF01127.22 KXS16238.1 - 1.8e-16 60.3 3.8 3.2e-16 59.5 3.8 1.4 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit PHM7_cyt PF14703.6 KXS16240.1 - 7.6e-09 36.0 0.0 2.8e-08 34.2 0.0 1.7 1 1 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 KXS16240.1 - 1.2e-08 34.8 0.4 2e-08 34.1 0.4 1.3 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport Arm PF00514.23 KXS16242.1 - 6.3e-05 22.9 14.6 9.4 6.4 0.0 9.2 10 1 0 10 10 10 4 Armadillo/beta-catenin-like repeat Tti2 PF10521.9 KXS16242.1 - 0.045 13.3 0.0 0.15 11.6 0.0 2.0 1 0 0 1 1 1 0 Tti2 family NAD_binding_1 PF00175.21 KXS16243.1 - 3.3e-06 27.7 0.0 5.6e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 KXS16243.1 - 0.0055 16.8 0.0 0.012 15.7 0.0 1.6 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KXS16243.1 - 0.053 13.6 0.0 0.095 12.8 0.0 1.3 1 0 0 1 1 1 0 FAD-binding domain MoCF_biosynth PF00994.24 KXS16243.1 - 0.14 11.8 0.1 0.39 10.4 0.0 1.7 2 1 0 2 2 2 0 Probable molybdopterin binding domain tRNA_SAD PF07973.14 KXS16243.1 - 0.14 12.3 0.0 0.3 11.2 0.0 1.5 1 0 0 1 1 1 0 Threonyl and Alanyl tRNA synthetase second additional domain zf-MYND PF01753.18 KXS16244.1 - 0.021 14.9 0.6 0.066 13.3 0.6 1.9 1 0 0 1 1 1 0 MYND finger TM140 PF14985.6 KXS16244.1 - 0.024 14.2 0.1 0.051 13.1 0.1 1.6 1 0 0 1 1 1 0 TM140 protein family NTP_transf_2 PF01909.23 KXS16245.1 - 3.1e-12 46.6 0.0 7e-12 45.5 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 KXS16245.1 - 0.032 14.3 0.0 0.059 13.5 0.0 1.4 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase AA_synth PF06684.11 KXS16246.1 - 0.14 11.6 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 Amino acid synthesis DUF5323 PF17257.2 KXS16248.1 - 0.11 12.4 2.2 0.22 11.4 2.2 1.5 1 1 0 1 1 1 0 Family of unknown function (DUF5323) RRM_1 PF00076.22 KXS16249.1 - 5.7e-38 128.6 0.0 1.2e-18 66.7 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KXS16249.1 - 3.3e-07 30.3 0.1 8e-06 25.9 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif OB_RNB PF08206.11 KXS16249.1 - 7e-06 25.6 0.2 0.15 11.7 0.1 2.4 2 0 0 2 2 2 2 Ribonuclease B OB domain RRM_5 PF13893.6 KXS16249.1 - 5.7e-05 22.7 0.0 0.26 10.9 0.0 2.4 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KXS16249.1 - 0.0046 16.8 0.0 0.023 14.6 0.0 2.0 2 0 0 2 2 2 1 Occluded RNA-recognition motif PHM7_cyt PF14703.6 KXS16249.1 - 0.04 14.2 0.0 3.3 7.9 0.0 2.3 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter Nup35_RRM_2 PF14605.6 KXS16249.1 - 0.11 12.5 0.0 4.7 7.3 0.0 2.5 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif AA_permease_2 PF13520.6 KXS16250.1 - 3.2e-38 131.7 42.4 4.5e-38 131.2 42.4 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXS16250.1 - 4.4e-12 45.3 44.9 3.2e-10 39.2 44.9 2.7 1 1 0 1 1 1 1 Amino acid permease PIN_4 PF13638.6 KXS16252.1 - 5.4e-06 26.7 0.0 5.5e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 PIN domain ABC_membrane_2 PF06472.15 KXS16254.1 - 2.4e-97 325.6 3.0 3.2e-97 325.1 3.0 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 KXS16254.1 - 2.8e-16 60.3 0.0 7.1e-16 59.0 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KXS16254.1 - 0.0013 18.6 0.0 0.0036 17.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KXS16254.1 - 0.0067 16.9 2.5 0.01 16.4 0.0 2.4 3 0 0 3 3 3 1 AAA domain SbmA_BacA PF05992.12 KXS16254.1 - 0.0071 15.8 0.3 0.013 15.0 0.3 1.4 1 0 0 1 1 1 1 SbmA/BacA-like family NACHT PF05729.12 KXS16254.1 - 0.0082 16.1 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 NACHT domain DUF3584 PF12128.8 KXS16254.1 - 0.014 13.0 0.0 0.027 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_29 PF13555.6 KXS16254.1 - 0.023 14.4 0.0 0.069 12.9 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 KXS16254.1 - 0.029 14.7 0.0 0.075 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain SMC_N PF02463.19 KXS16254.1 - 0.03 13.8 0.2 0.13 11.7 0.0 2.0 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain Mg_chelatase PF01078.21 KXS16254.1 - 0.11 11.9 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI BCDHK_Adom3 PF10436.9 KXS16257.1 - 3.2e-56 189.6 0.0 1.1e-55 187.9 0.0 1.8 2 0 0 2 2 2 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KXS16257.1 - 9.6e-12 45.4 0.0 1.7e-11 44.6 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KXS16257.1 - 0.004 17.0 0.0 0.0069 16.2 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Pkinase_Tyr PF07714.17 KXS16260.1 - 9.9e-06 25.0 0.0 1.3e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXS16260.1 - 0.02 14.3 0.0 0.026 13.9 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain P53 PF00870.18 KXS16260.1 - 0.021 14.6 0.1 0.044 13.6 0.1 1.4 1 1 0 1 1 1 0 P53 DNA-binding domain MFS_1 PF07690.16 KXS16262.1 - 1.2e-28 100.1 36.8 1.4e-28 99.8 36.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 KXS16262.1 - 5.4e-06 25.2 9.5 1.8e-05 23.5 0.4 2.7 2 1 0 2 2 2 2 MFS/sugar transport protein DEAD PF00270.29 KXS16263.1 - 3.4e-42 144.2 0.0 5.1e-42 143.6 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXS16263.1 - 7.9e-19 68.0 0.0 2.2e-18 66.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KXS16263.1 - 4.3e-17 62.1 0.1 1.1e-16 60.8 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KXS16263.1 - 1.1e-06 28.7 0.0 2.5e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KXS16263.1 - 0.0082 15.4 0.0 0.014 14.6 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase SBF_like PF13593.6 KXS16263.1 - 0.012 14.9 0.0 0.017 14.4 0.0 1.1 1 0 0 1 1 1 0 SBF-like CPA transporter family (DUF4137) DUF4880 PF16220.5 KXS16263.1 - 0.028 14.3 0.6 0.089 12.7 0.6 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4880) PRIMA1 PF16101.5 KXS16263.1 - 0.18 11.9 1.4 0.47 10.5 1.4 1.7 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 CMS1 PF14617.6 KXS16263.1 - 0.81 9.0 0.0 0.81 9.0 0.0 3.1 3 1 1 4 4 4 0 U3-containing 90S pre-ribosomal complex subunit Ebp2 PF05890.12 KXS16264.1 - 4.9e-56 190.2 17.1 4.9e-56 190.2 17.1 2.8 1 1 1 2 2 2 1 Eukaryotic rRNA processing protein EBP2 GvpL_GvpF PF06386.11 KXS16264.1 - 0.16 11.9 17.3 0.085 12.8 6.7 2.1 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF SET PF00856.28 KXS16264.1 - 0.75 10.2 6.3 5.1 7.5 0.7 2.2 1 1 1 2 2 2 0 SET domain RR_TM4-6 PF06459.12 KXS16264.1 - 9.8 5.9 17.1 0.51 10.1 4.4 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Exo_endo_phos PF03372.23 KXS16265.1 - 1.9e-15 57.0 0.2 3.4e-15 56.2 0.2 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Aa_trans PF01490.18 KXS16266.1 - 1.2e-61 208.7 9.9 1.2e-60 205.4 9.9 2.0 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Pkinase PF00069.25 KXS16268.1 - 2.3e-51 174.7 0.0 5.3e-51 173.5 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS16268.1 - 5.4e-16 58.7 0.2 4.1e-15 55.8 0.2 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KXS16268.1 - 0.13 11.6 0.4 0.22 10.9 0.4 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXS16268.1 - 0.18 11.7 0.3 0.71 9.7 0.3 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family FA_hydroxylase PF04116.13 KXS16269.1 - 1.2e-21 77.4 12.6 2.6e-21 76.4 12.6 1.6 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily Abhydrolase_6 PF12697.7 KXS16271.1 - 1.2e-05 26.0 0.0 1.6e-05 25.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KXS16271.1 - 0.001 18.6 0.0 0.0021 17.6 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family AXE1 PF05448.12 KXS16271.1 - 0.013 14.2 0.0 0.019 13.7 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Abhydrolase_3 PF07859.13 KXS16271.1 - 0.047 13.5 0.0 0.079 12.8 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Aminotran_1_2 PF00155.21 KXS16272.1 - 2.1e-58 198.3 0.0 2.6e-58 198.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 KXS16272.1 - 0.0017 17.7 0.0 0.0029 17.0 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase OKR_DC_1 PF01276.20 KXS16272.1 - 0.0084 14.9 0.0 0.017 13.9 0.0 1.4 1 1 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain Cys_Met_Meta_PP PF01053.20 KXS16272.1 - 0.18 10.3 0.0 0.33 9.5 0.0 1.4 1 1 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme SIR2 PF02146.17 KXS16273.1 - 3.5e-32 111.8 0.0 2.8e-24 86.0 0.0 2.2 1 1 1 2 2 2 2 Sir2 family TPP_enzyme_M PF00205.22 KXS16273.1 - 0.0095 15.7 0.0 4.6 7.0 0.0 2.3 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain Zn-ribbon_8 PF09723.10 KXS16273.1 - 0.057 13.5 1.4 0.15 12.2 1.4 1.7 1 1 0 1 1 1 0 Zinc ribbon domain zf-TFIIB PF13453.6 KXS16273.1 - 0.1 11.9 0.8 14 5.1 0.1 2.6 2 0 0 2 2 2 0 Transcription factor zinc-finger DUF2263 PF10021.9 KXS16274.1 - 5.6e-19 69.0 0.0 1.2e-18 67.9 0.0 1.5 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) TFIIA PF03153.13 KXS16275.1 - 2.2e-61 209.1 2.8 3.3e-61 208.5 2.8 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Cwf_Cwc_15 PF04889.12 KXS16275.1 - 7.5 6.2 10.3 1.3 8.7 5.2 1.9 1 1 1 2 2 2 0 Cwf15/Cwc15 cell cycle control protein RNA_pol_A_bac PF01000.26 KXS16276.1 - 6e-33 113.6 0.0 9.4e-33 112.9 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 KXS16276.1 - 2.1e-19 68.7 0.0 2.6e-19 68.4 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain GST_N_3 PF13417.6 KXS16277.1 - 4.9e-14 52.5 0.0 8.9e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KXS16277.1 - 1.3e-13 51.1 0.0 2.5e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KXS16277.1 - 4e-12 46.2 0.0 6.5e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KXS16277.1 - 6e-11 42.5 0.0 1.2e-10 41.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KXS16277.1 - 8e-11 42.0 0.0 1.2e-10 41.4 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KXS16277.1 - 1.3e-06 28.3 0.0 2.1e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain MFS_1 PF07690.16 KXS16281.1 - 1.4e-53 182.1 44.7 1.4e-53 182.1 44.7 2.2 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KXS16281.1 - 2.9e-21 75.5 21.7 4.2e-21 75.0 21.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KXS16281.1 - 1.2e-07 31.0 13.5 1.2e-07 31.0 13.5 3.5 3 2 1 4 4 4 3 Sugar (and other) transporter OATP PF03137.20 KXS16281.1 - 0.00057 18.3 3.6 0.00057 18.3 3.6 3.5 2 2 1 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family MFS_2 PF13347.6 KXS16281.1 - 0.0021 16.7 6.0 0.0021 16.7 6.0 4.2 3 1 1 4 4 4 2 MFS/sugar transport protein DUF647 PF04884.14 KXS16281.1 - 0.16 11.6 2.7 0.3 10.7 0.4 2.3 2 0 0 2 2 2 0 Vitamin B6 photo-protection and homoeostasis MFS_1 PF07690.16 KXS16282.1 - 4.9e-52 177.0 44.2 4.9e-52 177.0 44.2 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KXS16282.1 - 3.1e-25 88.6 21.7 4.2e-25 88.2 21.7 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KXS16282.1 - 8.1e-10 38.1 11.5 8.1e-10 38.1 11.5 3.9 2 1 1 3 3 3 2 Sugar (and other) transporter Peptidase_S9 PF00326.21 KXS16283.1 - 0.011 15.2 0.0 0.011 15.2 0.0 1.1 1 0 0 1 1 1 0 Prolyl oligopeptidase family Axin_b-cat_bind PF08833.10 KXS16283.1 - 2.8 8.1 4.7 12 6.2 4.7 2.0 1 1 0 1 1 1 0 Axin beta-catenin binding domain Rhodanese PF00581.20 KXS16284.1 - 1.9e-05 25.1 0.1 0.00015 22.2 0.1 2.2 1 1 0 1 1 1 1 Rhodanese-like domain FLYWCH_N PF15423.6 KXS16284.1 - 0.0074 16.4 0.0 0.86 9.7 0.0 2.9 2 1 0 2 2 2 1 FLYWCH-type zinc finger-containing protein HEAT PF02985.22 KXS16285.1 - 5.5e-19 66.6 10.7 0.095 13.0 0.1 7.7 7 0 0 7 7 7 6 HEAT repeat Arm PF00514.23 KXS16285.1 - 5.6e-17 61.2 15.9 0.00084 19.3 0.0 7.7 9 0 0 9 9 9 5 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 KXS16285.1 - 1.1e-13 51.4 22.1 0.00072 19.9 0.4 5.1 1 1 3 5 5 5 5 HEAT repeats HEAT_EZ PF13513.6 KXS16285.1 - 1.1e-11 45.0 28.5 0.00054 20.4 1.0 6.2 4 2 2 6 6 6 5 HEAT-like repeat Cnd1 PF12717.7 KXS16285.1 - 3.9e-10 40.0 0.0 0.0079 16.2 0.0 3.6 4 0 0 4 4 4 3 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 KXS16285.1 - 6.7e-06 25.8 0.0 0.0033 17.0 0.0 3.1 2 1 0 2 2 2 1 CLASP N terminal DNA_alkylation PF08713.11 KXS16285.1 - 1.8e-05 24.6 0.3 0.35 10.6 0.0 4.0 3 2 0 3 3 3 2 DNA alkylation repair enzyme Adaptin_N PF01602.20 KXS16285.1 - 0.00028 19.6 0.0 2.7 6.4 0.0 3.7 3 1 1 4 4 4 2 Adaptin N terminal region Gcn1_N PF12074.8 KXS16285.1 - 0.035 13.4 1.1 1.6 8.0 0.0 3.2 2 1 1 3 3 3 0 Generalcontrol nonderepressible 1 (Gcn1) N-terminal Proteasom_PSMB PF10508.9 KXS16285.1 - 0.069 11.6 0.1 0.77 8.2 0.1 2.3 1 1 0 2 2 2 0 Proteasome non-ATPase 26S subunit Caerin_1 PF07440.12 KXS16285.1 - 0.092 12.8 0.7 2.6 8.2 0.1 2.7 2 0 0 2 2 2 0 Caerin 1 protein LAMTOR5 PF16672.5 KXS16288.1 - 2.9e-13 49.6 0.0 3.8e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 Ragulator complex protein LAMTOR5 Robl_LC7 PF03259.17 KXS16288.1 - 0.011 15.5 0.1 0.015 15.1 0.1 1.4 1 1 0 1 1 1 0 Roadblock/LC7 domain Ion_trans_2 PF07885.16 KXS16289.1 - 2.6e-27 94.6 26.0 2.6e-14 52.9 3.3 2.8 3 0 0 3 3 3 2 Ion channel Lig_chan PF00060.26 KXS16289.1 - 0.065 13.1 0.1 0.065 13.1 0.1 2.4 3 0 0 3 3 3 0 Ligand-gated ion channel Ion_trans PF00520.31 KXS16289.1 - 0.36 10.0 13.5 0.25 10.5 1.0 2.9 2 1 0 2 2 2 0 Ion transport protein DUF3156 PF11354.8 KXS16290.1 - 0.082 12.8 0.2 0.21 11.5 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3156) PPR_2 PF13041.6 KXS16290.1 - 0.082 13.1 0.0 1.8 8.8 0.0 2.8 3 0 0 3 3 3 0 PPR repeat family GATA PF00320.27 KXS16291.1 - 3.4e-12 45.8 4.1 6.6e-12 44.8 4.1 1.5 1 0 0 1 1 1 1 GATA zinc finger DUF4402 PF14352.6 KXS16291.1 - 0.072 13.7 0.0 0.22 12.2 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4402) zf-NADH-PPase PF09297.11 KXS16291.1 - 0.18 11.5 4.2 7.1 6.4 0.6 2.5 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain MPC PF03650.13 KXS16293.1 - 5.3e-32 110.2 0.2 6.4e-32 110.0 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers MatE PF01554.18 KXS16294.1 - 2.3e-43 147.6 34.7 2.4e-22 79.3 6.7 3.3 3 1 0 3 3 3 2 MatE FKBP_C PF00254.28 KXS16295.1 - 4.3e-37 126.3 0.0 5.9e-37 125.9 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase DUF5325 PF17259.2 KXS16295.1 - 0.1 12.5 0.1 0.17 11.7 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5325) PfkB PF00294.24 KXS16296.1 - 3.9e-71 239.8 0.1 4.8e-71 239.5 0.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 KXS16296.1 - 0.023 14.1 0.0 0.044 13.2 0.0 1.4 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase WH1 PF00568.23 KXS16296.1 - 0.14 12.1 0.3 0.26 11.2 0.3 1.4 1 0 0 1 1 1 0 WH1 domain DUF4133 PF13571.6 KXS16297.1 - 0.058 13.7 2.7 0.84 10.0 0.1 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4133) SLATT_1 PF18181.1 KXS16297.1 - 1.4 8.9 4.8 2.5 8.1 0.0 2.7 2 1 1 3 3 3 0 SMODS and SLOG-associating 2TM effector domain 1 Smg8_Smg9 PF10220.9 KXS16299.1 - 3.8e-18 65.3 4.0 1.5e-12 46.8 2.7 3.2 3 0 0 3 3 3 3 Smg8_Smg9 Glyco_hydro_47 PF01532.20 KXS16300.1 - 1.2e-158 528.8 0.0 1.4e-158 528.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 GP88 PF17338.2 KXS16300.1 - 0.096 12.1 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Gene product 88 tRNA_edit PF04073.15 KXS16301.1 - 6.9e-12 45.5 0.0 2.6e-11 43.7 0.0 1.8 1 1 0 1 1 1 1 Aminoacyl-tRNA editing domain 2OG-FeII_Oxy PF03171.20 KXS16302.1 - 2.8e-13 50.2 0.0 5.4e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 KXS16302.1 - 3.7e-08 34.1 0.0 6.4e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Aminotran_4 PF01063.19 KXS16303.1 - 9.4e-26 91.0 0.0 1.4e-25 90.5 0.0 1.2 1 0 0 1 1 1 1 Amino-transferase class IV Sulfotransfer_3 PF13469.6 KXS16303.1 - 0.01 16.2 0.0 0.017 15.5 0.0 1.5 1 0 0 1 1 1 0 Sulfotransferase family Tox-REase-2 PF15646.6 KXS16305.1 - 0.091 12.9 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 Restriction endonuclease fold toxin 2 Vps35 PF03635.17 KXS16312.1 - 2e-233 777.1 0.0 3.4e-181 604.4 0.0 2.0 2 0 0 2 2 2 2 Vacuolar protein sorting-associated protein 35 SIMPL PF04402.14 KXS16312.1 - 0.0066 16.9 0.4 0.017 15.5 0.4 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF541) PNP_UDP_1 PF01048.20 KXS16312.1 - 0.05 12.8 0.7 0.092 12.0 0.7 1.3 1 0 0 1 1 1 0 Phosphorylase superfamily DUF758 PF05527.11 KXS16312.1 - 0.37 10.8 1.5 0.55 10.2 0.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF758) MAGE_N PF12440.8 KXS16312.1 - 6.4 7.5 11.1 4.6 8.0 2.1 3.4 3 0 0 3 3 3 0 Melanoma associated antigen family N terminal Glyco_transf_90 PF05686.12 KXS16313.1 - 3.9e-11 42.5 0.1 6.8e-11 41.7 0.1 1.4 1 1 0 1 1 1 1 Glycosyl transferase family 90 Hexapep PF00132.24 KXS16314.1 - 8.3e-12 44.4 17.8 3.9e-05 23.2 7.4 5.0 3 1 1 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KXS16314.1 - 2.3e-07 30.4 14.4 0.00012 21.8 2.9 3.7 3 1 2 5 5 5 4 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 KXS16314.1 - 0.26 10.2 0.0 0.42 9.5 0.0 1.3 1 0 0 1 1 1 0 L-fucokinase zf-MYND PF01753.18 KXS16318.1 - 5.6e-08 32.7 12.9 1.1e-07 31.9 12.9 1.5 1 0 0 1 1 1 1 MYND finger zf-ribbon_3 PF13248.6 KXS16318.1 - 0.0023 17.3 0.7 0.0053 16.1 0.7 1.6 1 0 0 1 1 1 1 zinc-ribbon domain Neur_chan_memb PF02932.16 KXS16322.1 - 0.079 13.0 0.9 0.13 12.3 0.9 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PDZ_5 PF17817.1 KXS16322.1 - 0.18 12.1 0.1 0.97 9.8 0.0 2.1 2 0 0 2 2 2 0 PDZ domain Pyr_redox_2 PF07992.14 KXS16324.1 - 6.7e-30 104.3 0.0 8.9e-30 103.9 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXS16324.1 - 4.2e-10 40.0 1.0 1.4e-07 32.0 0.2 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXS16324.1 - 1.9e-06 27.4 0.0 7.3e-06 25.5 0.0 1.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXS16324.1 - 0.00065 18.9 0.0 0.0017 17.5 0.0 1.6 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.14 KXS16324.1 - 0.013 14.4 3.5 4.6 6.0 0.0 3.1 2 1 1 3 3 3 0 Tryptophan halogenase MTS_N PF08468.11 KXS16324.1 - 0.2 11.7 0.0 0.43 10.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain N-terminal Abhydrolase_6 PF12697.7 KXS16325.1 - 1.1e-14 55.6 0.0 1.5e-14 55.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXS16325.1 - 1.1e-07 31.3 0.0 4.6e-06 26.1 0.0 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KXS16325.1 - 7e-05 22.6 0.0 0.0017 18.0 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 KXS16325.1 - 0.0028 17.3 0.0 0.0048 16.6 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 KXS16325.1 - 0.054 13.0 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family NifU_N PF01592.16 KXS16326.1 - 2.6e-50 169.9 0.0 3.8e-50 169.3 0.0 1.2 1 0 0 1 1 1 1 NifU-like N terminal domain DSBA PF01323.20 KXS16327.1 - 1.9e-21 76.7 0.0 3.3e-10 40.1 0.0 2.3 2 0 0 2 2 2 2 DSBA-like thioredoxin domain F-box-like PF12937.7 KXS16328.1 - 8.6e-12 44.8 5.9 5.2e-06 26.3 1.0 3.4 2 0 0 2 2 2 2 F-box-like F-box PF00646.33 KXS16328.1 - 0.00019 21.2 1.9 0.007 16.2 0.6 2.8 2 0 0 2 2 2 1 F-box domain F-box-like_2 PF13013.6 KXS16328.1 - 0.032 14.2 0.0 1.1 9.3 0.0 2.4 2 0 0 2 2 2 0 F-box-like domain Zn_Tnp_IS1 PF03811.13 KXS16328.1 - 0.058 13.1 5.1 3 7.6 0.2 3.1 3 0 0 3 3 3 0 InsA N-terminal domain Reeler PF02014.16 KXS16329.1 - 3.6e-08 34.2 0.0 5.5e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Reeler domain GST_N_3 PF13417.6 KXS16330.1 - 8.7e-12 45.3 0.0 2.2e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KXS16330.1 - 4.6e-10 39.7 0.0 8.7e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KXS16330.1 - 5.8e-10 39.4 0.0 9.7e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain zf-MYND PF01753.18 KXS16331.1 - 3.3e-09 36.7 11.0 6e-09 35.8 11.0 1.5 1 0 0 1 1 1 1 MYND finger DUF5054 PF16477.5 KXS16332.1 - 3.4e-21 76.3 0.4 3.2e-12 46.9 1.0 3.2 2 1 0 2 2 2 2 Domain of unknown function (DUF5054) GST_N_3 PF13417.6 KXS16333.1 - 2.7e-12 46.9 0.0 4.9e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KXS16333.1 - 1.6e-09 37.9 0.0 2.8e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KXS16333.1 - 6.5e-08 32.8 0.0 1.3e-07 31.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Tom37 PF10568.9 KXS16333.1 - 0.023 15.0 0.0 0.037 14.3 0.0 1.3 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein GST_N_4 PF17172.4 KXS16333.1 - 0.11 13.3 0.0 0.21 12.4 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain T5orf172 PF10544.9 KXS16334.1 - 2e-12 47.6 0.0 3.5e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 KXS16334.1 - 3.4e-11 43.7 0.0 5.5e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 Reeler PF02014.16 KXS16335.1 - 2.2e-05 25.2 0.0 3.6e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Reeler domain FlhE PF06366.13 KXS16335.1 - 0.02 14.9 0.0 0.052 13.5 0.0 1.7 1 0 0 1 1 1 0 Flagellar protein FlhE Telomere_reg-2 PF10193.9 KXS16336.1 - 2.3e-19 69.8 0.0 1.2e-18 67.5 0.0 2.0 1 1 0 1 1 1 1 Telomere length regulation protein DUF4266 PF14086.6 KXS16336.1 - 0.044 14.7 0.3 0.044 14.7 0.3 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4266) Tmemb_170 PF10190.9 KXS16338.1 - 8e-06 26.2 1.7 1.1e-05 25.7 1.7 1.1 1 0 0 1 1 1 1 Putative transmembrane protein 170 LETM1 PF07766.13 KXS16341.1 - 4.6e-14 52.4 0.0 1.1e-13 51.2 0.0 1.5 1 1 0 1 1 1 1 LETM1-like protein Ank PF00023.30 KXS16342.1 - 0.03 14.8 0.0 2.7 8.6 0.0 3.0 3 0 0 3 3 3 0 Ankyrin repeat Ank_5 PF13857.6 KXS16342.1 - 0.048 14.0 0.1 7.7 7.0 0.1 3.5 3 1 0 3 3 3 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXS16342.1 - 0.12 13.0 0.0 4.3 8.2 0.0 2.6 2 0 0 2 2 2 0 Ankyrin repeat adh_short PF00106.25 KXS16345.1 - 1.2e-31 109.7 0.2 1.9e-31 109.1 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXS16345.1 - 5.9e-19 68.6 0.1 1e-18 67.8 0.1 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXS16345.1 - 1.4e-05 25.1 1.9 5.7e-05 23.1 1.9 1.9 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.10 KXS16345.1 - 0.063 12.6 0.0 5.5 6.3 0.0 2.3 2 1 0 2 2 2 0 Fungal family of unknown function (DUF1776) DUF2306 PF10067.9 KXS16346.1 - 1.2e-06 28.8 2.0 2.4e-06 27.8 1.9 1.6 1 1 0 1 1 1 1 Predicted membrane protein (DUF2306) EF_assoc_2 PF08356.12 KXS16346.1 - 0.03 14.3 0.0 0.055 13.5 0.0 1.4 1 0 0 1 1 1 0 EF hand associated Cytochrom_B561 PF03188.16 KXS16347.1 - 1.6 8.8 10.8 0.58 10.3 5.7 2.3 2 0 0 2 2 2 0 Eukaryotic cytochrome b561 N2227 PF07942.12 KXS16349.1 - 1.9e-17 63.3 0.0 6.4e-17 61.6 0.0 1.8 1 1 0 1 1 1 1 N2227-like protein AP_endonuc_2 PF01261.24 KXS16351.1 - 6.4e-28 97.6 0.0 5e-27 94.7 0.0 2.0 1 1 1 2 2 2 2 Xylose isomerase-like TIM barrel HpaB_N PF11794.8 KXS16351.1 - 0.091 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Vinculin PF01044.19 KXS16352.1 - 2.4e-39 135.4 21.7 3.2e-20 72.0 15.9 2.2 2 0 0 2 2 2 2 Vinculin family Mito_carr PF00153.27 KXS16354.1 - 7.6e-16 57.8 1.2 1.4e-06 28.2 0.1 4.4 3 2 0 3 3 3 3 Mitochondrial carrier protein PRKCSH-like PF12999.7 KXS16355.1 - 4e-43 147.3 0.6 6.4e-43 146.6 0.6 1.2 1 0 0 1 1 1 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 KXS16355.1 - 6.3e-21 74.7 0.1 1.3e-20 73.6 0.1 1.5 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 KXS16355.1 - 2.9e-07 31.4 0.9 8.4e-07 29.9 0.9 1.9 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein Ldl_recept_a PF00057.18 KXS16355.1 - 0.018 15.2 1.9 0.018 15.2 1.9 2.7 1 1 1 2 2 2 0 Low-density lipoprotein receptor domain class A DUF3138 PF11336.8 KXS16355.1 - 0.046 12.3 0.8 0.067 11.8 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Pox_A_type_inc PF04508.12 KXS16355.1 - 0.063 13.2 0.3 15 5.6 0.1 2.5 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat CENP-F_leu_zip PF10473.9 KXS16355.1 - 0.13 12.3 4.4 0.24 11.4 3.1 1.9 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FlxA PF14282.6 KXS16355.1 - 0.18 11.8 0.8 0.33 10.9 0.8 1.3 1 0 0 1 1 1 0 FlxA-like protein DUF4140 PF13600.6 KXS16355.1 - 0.39 11.2 2.5 1.8 9.0 1.8 2.2 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) ABC_tran_CTD PF16326.5 KXS16355.1 - 0.57 10.5 6.6 0.73 10.1 4.0 2.2 2 0 0 2 2 2 0 ABC transporter C-terminal domain DUF724 PF05266.14 KXS16355.1 - 2.3 8.0 5.9 2 8.2 4.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF724) SH3_9 PF14604.6 KXS16356.1 - 6.9e-10 38.6 0.0 1.5e-08 34.3 0.0 2.4 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 KXS16356.1 - 8.4e-06 25.3 0.0 3.2e-05 23.5 0.0 1.9 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 KXS16356.1 - 0.0029 17.3 0.0 0.0063 16.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Fez1 PF06818.15 KXS16356.1 - 0.03 14.8 21.2 0.12 12.8 15.0 2.3 1 1 1 2 2 2 0 Fez1 Filament PF00038.21 KXS16356.1 - 0.14 11.7 22.0 0.076 12.6 7.7 3.3 2 2 1 3 3 3 0 Intermediate filament protein FlaC_arch PF05377.11 KXS16356.1 - 0.18 12.2 8.5 15 6.0 0.1 4.1 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) Spc7 PF08317.11 KXS16356.1 - 0.28 10.0 23.8 0.017 14.0 15.6 2.2 2 1 0 3 3 3 0 Spc7 kinetochore protein Cnn_1N PF07989.11 KXS16356.1 - 0.43 10.8 13.7 21 5.3 0.1 4.2 4 0 0 4 4 4 0 Centrosomin N-terminal motif 1 DUF4407 PF14362.6 KXS16356.1 - 0.72 9.2 17.7 3.3 7.0 13.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Fib_alpha PF08702.10 KXS16356.1 - 1.2 9.4 11.3 0.26 11.5 5.0 2.5 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family HAUS-augmin3 PF14932.6 KXS16356.1 - 1.2 8.7 13.3 0.13 11.9 7.9 2.0 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 GBP_C PF02841.14 KXS16356.1 - 1.4 8.3 15.5 0.21 10.9 9.8 2.0 2 0 0 2 2 2 0 Guanylate-binding protein, C-terminal domain PIN_8 PF18476.1 KXS16356.1 - 1.5 8.7 6.7 3.6 7.4 6.7 1.6 1 0 0 1 1 1 0 PIN like domain HMMR_N PF15905.5 KXS16356.1 - 1.8 8.0 17.2 35 3.7 17.2 2.4 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal APG6_N PF17675.1 KXS16356.1 - 2.5 8.6 22.9 8.5 6.9 15.4 2.9 3 0 0 3 3 3 0 Apg6 coiled-coil region NPV_P10 PF05531.12 KXS16356.1 - 2.8 8.5 5.9 2.2 8.8 0.3 2.9 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein V_ATPase_I PF01496.19 KXS16356.1 - 3.2 5.5 6.0 0.33 8.8 1.2 1.6 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Occludin_ELL PF07303.13 KXS16356.1 - 3.4 8.4 7.8 3 8.6 3.6 2.7 2 1 1 3 3 3 0 Occludin homology domain Uds1 PF15456.6 KXS16356.1 - 4.2 7.5 25.2 0.44 10.7 1.9 2.6 1 1 2 3 3 3 0 Up-regulated During Septation HAP1_N PF04849.13 KXS16356.1 - 5 6.2 20.1 2.9 7.0 1.6 2.3 2 0 0 2 2 2 0 HAP1 N-terminal conserved region SH3_9 PF14604.6 KXS16357.1 - 1.3e-06 28.1 0.0 3.2e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXS16357.1 - 0.00025 20.6 0.0 0.00059 19.4 0.0 1.7 1 0 0 1 1 1 1 SH3 domain ATG16 PF08614.11 KXS16357.1 - 0.0003 21.1 19.1 0.0003 21.1 19.1 2.6 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) SH3_2 PF07653.17 KXS16357.1 - 0.0023 17.6 0.0 0.0044 16.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Baculo_PEP_C PF04513.12 KXS16357.1 - 0.32 11.0 3.3 0.38 10.8 0.1 2.4 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus SHE3 PF17078.5 KXS16357.1 - 2.9 7.6 22.4 3.6 7.2 16.8 2.2 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 Prominin PF05478.11 KXS16357.1 - 9.9 4.0 9.9 15 3.4 9.9 1.3 1 0 0 1 1 1 0 Prominin DUF4013 PF13197.6 KXS16358.1 - 0.039 13.8 4.4 1.7 8.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4013) adh_short_C2 PF13561.6 KXS16359.1 - 1.4e-20 73.8 0.1 1.7e-20 73.6 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXS16359.1 - 4.3e-08 32.8 0.0 6.2e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Ctr PF04145.15 KXS16360.1 - 1.4e-32 113.4 0.1 2e-32 112.9 0.1 1.2 1 0 0 1 1 1 1 Ctr copper transporter family tRNA-synt_1e PF01406.19 KXS16361.1 - 2e-104 349.2 0.0 4e-104 348.2 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 KXS16361.1 - 7.6e-08 31.5 0.6 0.0006 18.7 0.1 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1c PF00749.21 KXS16361.1 - 0.00038 19.4 1.0 0.034 13.0 0.0 3.0 3 0 0 3 3 3 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1 PF00133.22 KXS16361.1 - 0.00056 18.3 0.0 0.0012 17.2 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1f PF01921.18 KXS16361.1 - 0.054 12.4 0.2 1.2 8.0 0.0 2.5 3 0 0 3 3 3 0 tRNA synthetases class I (K) peroxidase PF00141.23 KXS16362.1 - 3.9e-11 43.1 0.0 4.7e-11 42.8 0.0 1.1 1 0 0 1 1 1 1 Peroxidase VirB7 PF17413.2 KXS16362.1 - 0.15 11.4 0.1 0.35 10.2 0.1 1.6 1 0 0 1 1 1 0 Outer membrane lipoprotein virB7 Syndecan PF01034.20 KXS16363.1 - 0.044 13.7 0.0 0.085 12.8 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain Spt20 PF12090.8 KXS16363.1 - 1.1 8.8 4.4 1.6 8.3 4.4 1.2 1 0 0 1 1 1 0 Spt20 family F-box PF00646.33 KXS16364.1 - 2.3e-05 24.1 1.5 6.8e-05 22.6 1.4 1.8 1 1 1 2 2 2 1 F-box domain F-box-like PF12937.7 KXS16364.1 - 5.7e-05 22.9 1.3 0.00012 21.9 0.8 1.8 1 1 1 2 2 2 1 F-box-like F-box_4 PF15966.5 KXS16364.1 - 0.013 15.4 0.2 0.019 14.8 0.2 1.4 1 1 0 1 1 1 0 F-box Fungal_trans PF04082.18 KXS16365.1 - 1.8e-17 63.3 0.0 3.6e-17 62.3 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Phytoreo_P8 PF07124.11 KXS16365.1 - 0.079 11.9 0.1 0.12 11.4 0.1 1.1 1 0 0 1 1 1 0 Phytoreovirus outer capsid protein P8 DUF1571 PF07608.11 KXS16365.1 - 0.1 12.1 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1571) Methyltransf_11 PF08241.12 KXS16366.1 - 8.4e-18 64.8 0.0 1.6e-17 63.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXS16366.1 - 1.8e-14 54.2 0.0 4.2e-14 53.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXS16366.1 - 6.5e-07 30.0 0.0 1.1e-06 29.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXS16366.1 - 7.2e-07 29.2 0.0 1.1e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXS16366.1 - 2.3e-05 24.2 0.0 7.6e-05 22.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXS16366.1 - 0.0043 16.4 0.0 0.0078 15.6 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.15 KXS16366.1 - 0.027 14.3 0.0 0.044 13.6 0.0 1.4 1 0 0 1 1 1 0 Hypothetical methyltransferase RrnaAD PF00398.20 KXS16366.1 - 0.1 11.6 0.0 0.19 10.7 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_PK PF05891.12 KXS16366.1 - 0.11 12.0 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase DREV PF05219.12 KXS16366.1 - 0.18 10.9 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Sec7 PF01369.20 KXS16367.1 - 2.9e-62 209.6 0.0 4.7e-62 208.9 0.0 1.4 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 KXS16367.1 - 9.3e-09 35.4 0.1 1e-06 28.7 0.0 3.2 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DCB PF16213.5 KXS16367.1 - 0.0037 16.9 0.0 0.016 14.9 0.0 2.0 2 0 0 2 2 2 1 Dimerisation and cyclophilin-binding domain of Mon2 Aldo_ket_red PF00248.21 KXS16368.1 - 4.7e-18 65.4 0.0 5.7e-18 65.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family RNase_P_Rpp14 PF01900.19 KXS16369.1 - 1.1e-11 44.9 0.0 1.5e-11 44.4 0.0 1.1 1 0 0 1 1 1 1 Rpp14/Pop5 family Bmt2 PF11968.8 KXS16369.1 - 0.1 12.4 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 Enterotoxin_HS1 PF08090.11 KXS16369.1 - 0.16 11.9 1.2 0.35 10.9 1.2 1.5 1 0 0 1 1 1 0 Heat stable E.coli enterotoxin 1 HSP70 PF00012.20 KXS16370.1 - 0.00016 20.0 0.1 0.001 17.4 0.1 1.8 1 1 0 1 1 1 1 Hsp70 protein GSHPx PF00255.19 KXS16371.1 - 3.2e-48 161.8 0.1 4.2e-48 161.4 0.1 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 KXS16371.1 - 1.9e-05 24.6 0.0 4.7e-05 23.3 0.0 1.8 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KXS16371.1 - 4.9e-05 23.1 0.0 0.0091 15.7 0.0 2.1 2 0 0 2 2 2 2 Redoxin Fungal_trans PF04082.18 KXS16372.1 - 7.2e-22 77.7 0.1 5.5e-21 74.8 0.1 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXS16372.1 - 4.1e-07 30.0 18.8 6.7e-07 29.3 18.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UBM PF14377.6 KXS16372.1 - 0.079 12.4 0.0 0.26 10.8 0.0 1.9 1 0 0 1 1 1 0 Ubiquitin binding region Herpes_UL21 PF03252.13 KXS16372.1 - 0.14 10.8 0.0 0.22 10.3 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL21 Melibiase_2 PF16499.5 KXS16373.1 - 1.6e-72 244.1 0.6 2.9e-53 180.9 0.4 2.2 2 0 0 2 2 2 2 Alpha galactosidase A Melibiase_C PF17801.1 KXS16373.1 - 2e-07 31.0 0.0 3.3e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 KXS16373.1 - 1e-05 24.7 0.0 1.9e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Melibiase Zn_clus PF00172.18 KXS16374.1 - 2.6e-09 37.0 14.6 4e-09 36.5 14.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gln-synt_N_2 PF16952.5 KXS16374.1 - 0.15 11.9 0.3 0.36 10.7 0.1 1.7 2 0 0 2 2 2 0 Glutamine synthetase N-terminal domain Fungal_trans PF04082.18 KXS16375.1 - 3.9e-14 52.3 0.0 7.2e-14 51.4 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain SET PF00856.28 KXS16376.1 - 9.1e-13 48.9 0.0 9.5e-13 48.9 0.0 1.1 1 0 0 1 1 1 1 SET domain Abhydrolase_6 PF12697.7 KXS16377.1 - 3.8e-16 60.4 2.8 4.8e-16 60.0 2.8 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXS16377.1 - 1.7e-11 44.3 0.0 3.5e-08 33.4 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXS16377.1 - 2.4e-11 43.4 0.0 1.7e-09 37.3 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 KXS16377.1 - 4.4e-05 22.5 0.0 6.9e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_5 PF12695.7 KXS16377.1 - 0.0014 18.5 0.0 0.33 10.7 0.0 2.7 3 0 0 3 3 3 1 Alpha/beta hydrolase family DEC-1_N PF04625.13 KXS16377.1 - 0.0059 15.7 0.2 0.007 15.4 0.2 1.1 1 0 0 1 1 1 1 DEC-1 protein, N-terminal region Abhydrolase_4 PF08386.10 KXS16377.1 - 0.012 15.7 0.0 0.021 14.9 0.0 1.3 1 0 0 1 1 1 0 TAP-like protein adh_short PF00106.25 KXS16378.1 - 1.4e-34 119.3 0.0 1.8e-34 118.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXS16378.1 - 7e-26 91.2 0.0 8.6e-26 90.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXS16378.1 - 7.5e-10 39.0 0.1 1.1e-09 38.4 0.1 1.3 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KXS16378.1 - 0.00014 21.8 0.6 0.00031 20.7 0.6 1.7 1 1 0 1 1 1 1 NAD(P)H-binding DUF1776 PF08643.10 KXS16378.1 - 0.0061 16.0 0.1 0.014 14.8 0.1 1.6 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 KXS16378.1 - 0.013 15.0 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family adh_short PF00106.25 KXS16379.1 - 3.6e-32 111.4 0.0 4.5e-32 111.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXS16379.1 - 2.2e-24 86.3 0.0 2.6e-24 86.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXS16379.1 - 2.7e-08 33.9 0.0 3.3e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KXS16379.1 - 0.00088 19.2 0.1 0.0013 18.6 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding DUF1776 PF08643.10 KXS16379.1 - 0.025 14.0 0.0 0.042 13.2 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 KXS16379.1 - 0.037 13.5 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Fungal_trans PF04082.18 KXS16380.1 - 1.4e-14 53.8 0.0 3.6e-14 52.4 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXS16380.1 - 7.4e-07 29.2 9.3 1.3e-06 28.4 9.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.22 KXS16381.1 - 1.2e-23 83.7 0.0 4.9e-23 81.6 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 CCDC92 PF14916.6 KXS16384.1 - 7.4e-10 38.4 0.5 3.2e-09 36.4 0.0 2.0 2 0 0 2 2 2 1 Coiled-coil domain of unknown function PAH PF02671.21 KXS16385.1 - 3.1e-06 27.2 0.0 5.4e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Paired amphipathic helix repeat Rep_fac_C PF08542.11 KXS16385.1 - 0.014 15.8 0.0 0.021 15.2 0.0 1.4 1 0 0 1 1 1 0 Replication factor C C-terminal domain SET PF00856.28 KXS16389.1 - 5.1e-07 30.2 0.0 0.00038 20.9 0.0 2.5 2 1 0 2 2 2 2 SET domain DUF1029 PF06269.12 KXS16390.1 - 0.18 12.0 0.0 0.42 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1029) Dimer_Tnp_hAT PF05699.14 KXS16392.1 - 8.8e-12 44.7 0.0 9.3e-12 44.6 0.0 1.0 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Zn_clus PF00172.18 KXS16393.1 - 3.6e-05 23.8 12.1 8.3e-05 22.6 12.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain OPA3 PF07047.12 KXS16394.1 - 3.3e-33 114.1 0.1 4.3e-33 113.8 0.1 1.1 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) ATP-synt PF00231.19 KXS16395.1 - 3.3e-75 253.4 5.9 3.7e-75 253.2 5.9 1.0 1 0 0 1 1 1 1 ATP synthase DUF2808 PF10989.8 KXS16395.1 - 0.026 14.5 0.1 2.1 8.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2808) Y_phosphatase3 PF13350.6 KXS16396.1 - 1.5e-31 110.2 0.2 9.3e-30 104.3 0.1 2.5 1 1 1 2 2 2 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 KXS16396.1 - 0.14 11.7 0.1 0.57 9.7 0.0 1.7 2 0 0 2 2 2 0 Protein-tyrosine phosphatase Rhodanese PF00581.20 KXS16396.1 - 0.16 12.5 0.0 0.86 10.1 0.0 2.1 1 1 0 1 1 1 0 Rhodanese-like domain FH2 PF02181.23 KXS16397.1 - 1.7e-54 185.4 3.5 1.7e-54 185.4 3.5 1.6 2 0 0 2 2 2 1 Formin Homology 2 Domain zf-4CXXC_R1 PF10497.9 KXS16402.1 - 2.7e-08 33.9 12.5 2.7e-08 33.9 12.5 2.8 2 1 0 2 2 2 1 Zinc-finger domain of monoamine-oxidase A repressor R1 ADH_zinc_N PF00107.26 KXS16403.1 - 7.7e-12 45.3 0.1 1.3e-11 44.6 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXS16403.1 - 8e-08 32.1 0.6 0.00025 20.9 0.2 2.5 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain FAD_binding_3 PF01494.19 KXS16405.1 - 1.7e-13 50.6 0.1 4.1e-07 29.6 0.2 2.1 1 1 1 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 KXS16405.1 - 2.2e-08 33.7 0.1 0.00063 19.1 0.1 2.1 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXS16405.1 - 1.2e-06 29.0 0.0 0.0016 19.0 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXS16405.1 - 4.5e-06 26.5 0.3 0.0039 16.8 0.2 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXS16405.1 - 8.9e-06 25.8 0.2 1.9e-05 24.8 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KXS16405.1 - 0.00013 21.2 0.0 0.00083 18.5 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 KXS16405.1 - 0.00085 18.1 0.1 0.065 11.9 0.1 2.1 2 0 0 2 2 2 2 HI0933-like protein GIDA PF01134.22 KXS16405.1 - 0.0091 15.1 0.3 0.0093 15.1 0.3 1.3 1 1 0 1 1 1 1 Glucose inhibited division protein A ApbA PF02558.16 KXS16405.1 - 0.084 12.5 0.1 0.19 11.4 0.1 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA T6SS-SciN PF12790.7 KXS16405.1 - 0.12 12.1 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 Type VI secretion lipoprotein, VasD, EvfM, TssJ, VC_A0113 NAD_binding_2 PF03446.15 KXS16405.1 - 0.13 12.5 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Trp_halogenase PF04820.14 KXS16405.1 - 0.16 10.8 0.0 0.24 10.2 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase FAD_binding_3 PF01494.19 KXS16406.1 - 3.3e-07 29.9 0.0 3.9e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain SE PF08491.10 KXS16406.1 - 0.0022 17.1 0.0 0.0026 16.9 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase DUF3619 PF12279.8 KXS16406.1 - 0.11 12.8 0.9 0.24 11.7 0.3 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3619) zf-MYND PF01753.18 KXS16407.1 - 2.5e-10 40.3 3.1 2.5e-10 40.3 3.1 1.6 2 0 0 2 2 2 1 MYND finger DND1_DSRM PF14709.7 KXS16407.1 - 0.012 15.8 0.0 0.22 11.8 0.0 2.2 2 0 0 2 2 2 0 double strand RNA binding domain from DEAD END PROTEIN 1 Cellulase PF00150.18 KXS16408.1 - 1e-18 67.8 2.9 5.7e-18 65.3 2.9 1.8 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Nop PF01798.18 KXS16409.1 - 2e-83 279.4 0.0 2e-83 279.4 0.0 1.8 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 KXS16409.1 - 3.5e-19 68.9 0.4 3.5e-19 68.9 0.4 2.1 2 0 0 2 2 2 1 NOP5NT (NUC127) domain ANAPC4 PF12896.7 KXS16409.1 - 0.064 12.7 0.1 0.46 9.9 0.0 2.4 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 4 RR_TM4-6 PF06459.12 KXS16409.1 - 3.6 7.3 15.3 5.9 6.6 15.3 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 BRE1 PF08647.11 KXS16411.1 - 0.00012 22.1 19.5 0.0002 21.4 1.7 4.4 3 2 2 5 5 5 2 BRE1 E3 ubiquitin ligase DASH_Dad2 PF08654.10 KXS16411.1 - 0.01 16.2 2.9 0.24 11.8 0.7 2.8 2 0 0 2 2 2 0 DASH complex subunit Dad2 DivIC PF04977.15 KXS16411.1 - 0.081 12.7 0.3 0.081 12.7 0.3 3.9 2 1 3 5 5 5 0 Septum formation initiator DUF5494 PF17598.2 KXS16411.1 - 0.16 12.1 2.4 0.18 11.9 0.6 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5494) Plk4_PB2 PF18409.1 KXS16411.1 - 0.61 10.8 6.9 3.4 8.4 0.5 3.6 1 1 3 4 4 4 0 Polo-like Kinase 4 Polo Box 2 Cep57_CLD PF14073.6 KXS16411.1 - 0.9 9.5 21.1 0.22 11.5 6.4 3.2 3 0 0 3 3 3 0 Centrosome localisation domain of Cep57 CHASE3 PF05227.13 KXS16411.1 - 1.2 9.1 19.7 0.32 10.9 0.9 3.7 1 1 3 4 4 4 0 CHASE3 domain Rx_N PF18052.1 KXS16411.1 - 1.4 9.2 0.0 1.4 9.2 0.0 3.9 3 2 0 3 3 3 0 Rx N-terminal domain Prominin PF05478.11 KXS16411.1 - 2.2 6.1 6.2 0.2 9.6 0.3 1.9 2 0 0 2 2 2 0 Prominin Syntaxin_2 PF14523.6 KXS16411.1 - 2.5 8.5 13.6 0.42 11.0 3.7 3.2 1 1 1 3 3 3 0 Syntaxin-like protein Med4 PF10018.9 KXS16411.1 - 2.8 7.6 7.9 0.1 12.3 1.0 2.1 2 1 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 DHR10 PF18595.1 KXS16411.1 - 4 7.5 27.7 0.34 11.0 3.3 4.1 3 1 1 4 4 4 0 Designed helical repeat protein 10 domain NPV_P10 PF05531.12 KXS16411.1 - 5.1 7.6 8.0 0.82 10.2 1.3 2.9 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein LMBR1 PF04791.16 KXS16412.1 - 7.8 5.3 6.3 10 4.9 6.3 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Cyclase PF04199.13 KXS16416.1 - 1e-26 93.8 0.0 1.3e-26 93.4 0.0 1.1 1 0 0 1 1 1 1 Putative cyclase SMP PF04927.12 KXS16418.1 - 3.4 8.2 10.7 3 8.4 9.2 1.7 1 1 0 1 1 1 0 Seed maturation protein SH3_1 PF00018.28 KXS16419.1 - 1.1e-13 50.5 4.0 6.6e-10 38.4 0.1 3.1 2 1 1 3 3 3 2 SH3 domain SH3_9 PF14604.6 KXS16419.1 - 1.8e-13 50.1 4.0 1.8e-07 30.9 0.1 3.0 2 1 1 3 3 3 2 Variant SH3 domain SH3_2 PF07653.17 KXS16419.1 - 3.1e-08 33.2 0.4 0.00018 21.2 0.0 2.8 2 1 1 3 3 3 2 Variant SH3 domain SH3_2 PF07653.17 KXS16421.1 - 0.0071 16.0 0.0 0.016 14.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SKG6 PF08693.10 KXS16421.1 - 0.011 15.1 0.8 0.024 14.1 0.8 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain SH3_9 PF14604.6 KXS16421.1 - 0.014 15.3 0.0 0.033 14.0 0.0 1.7 1 0 0 1 1 1 0 Variant SH3 domain Syndecan PF01034.20 KXS16421.1 - 0.039 13.9 0.7 0.075 13.0 0.7 1.4 1 0 0 1 1 1 0 Syndecan domain Gram_pos_anchor PF00746.21 KXS16421.1 - 0.11 12.4 6.7 0.84 9.6 6.7 2.4 1 1 0 1 1 1 0 LPXTG cell wall anchor motif SH3_1 PF00018.28 KXS16422.1 - 7.2e-13 47.9 0.4 2.5e-07 30.2 0.0 2.7 3 0 0 3 3 3 2 SH3 domain SH3_9 PF14604.6 KXS16422.1 - 8.9e-09 35.1 0.7 0.0023 17.8 0.0 2.5 3 0 0 3 3 3 2 Variant SH3 domain FAO_M PF16350.5 KXS16422.1 - 0.068 13.5 0.0 2.2 8.7 0.0 2.4 2 1 0 2 2 2 0 FAD dependent oxidoreductase central domain F-box-like PF12937.7 KXS16424.1 - 0.0003 20.6 2.0 0.00036 20.3 0.4 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KXS16424.1 - 0.15 12.0 2.9 0.14 12.1 0.5 2.2 2 0 0 2 2 2 0 F-box domain SH3_1 PF00018.28 KXS16425.1 - 0.0041 16.7 0.0 0.0092 15.6 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KXS16425.1 - 0.034 13.8 0.3 0.086 12.5 0.1 1.8 2 0 0 2 2 2 0 Variant SH3 domain zf-C4_ClpX PF06689.13 KXS16425.1 - 2.2 8.2 5.3 3.7 7.5 3.9 2.1 2 0 0 2 2 2 0 ClpX C4-type zinc finger GSK-3_bind PF05350.12 KXS16425.1 - 2.7 7.3 8.3 0.061 12.6 0.4 2.1 2 0 0 2 2 2 0 Glycogen synthase kinase-3 binding Pribosyltran PF00156.27 KXS16428.1 - 1.3e-20 73.5 0.0 1.7e-20 73.2 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain DUF3787 PF12655.7 KXS16428.1 - 0.041 13.8 0.0 0.072 13.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3787) DUF5448 PF17526.2 KXS16428.1 - 0.11 12.7 0.0 2.2 8.5 0.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5448) LRR_4 PF12799.7 KXS16430.1 - 1.7e-05 25.1 2.5 0.015 15.7 0.1 2.5 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KXS16430.1 - 0.0018 17.8 0.0 0.0034 16.9 0.0 1.4 1 0 0 1 1 1 1 Leucine-rich repeat Ank_2 PF12796.7 KXS16431.1 - 0.0032 18.0 0.2 0.014 15.9 0.2 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXS16431.1 - 0.0077 16.8 1.0 0.81 10.3 0.0 2.5 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXS16431.1 - 0.034 14.5 0.2 0.27 11.6 0.0 2.3 2 1 1 3 3 3 0 Ankyrin repeats (many copies) HlyIII PF03006.20 KXS16432.1 - 4e-36 124.8 23.3 5.1e-36 124.5 23.3 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF962 PF06127.11 KXS16432.1 - 0.0017 18.4 0.9 0.021 14.9 0.9 2.4 1 1 0 1 1 1 1 Protein of unknown function (DUF962) HlyIII PF03006.20 KXS16433.1 - 2.1e-31 109.4 22.9 2.7e-31 109.1 22.9 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF962 PF06127.11 KXS16433.1 - 0.00019 21.5 0.0 0.0013 18.7 0.0 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF962) HlyIII PF03006.20 KXS16434.1 - 6.7e-35 120.8 16.6 8.5e-35 120.5 16.6 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF962 PF06127.11 KXS16434.1 - 0.025 14.6 0.1 0.11 12.6 0.1 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF962) Zip PF02535.22 KXS16434.1 - 0.16 11.2 3.9 0.24 10.6 3.9 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Trp_oprn_chp PF09534.10 KXS16434.1 - 1.9 8.3 5.6 0.98 9.2 0.9 2.6 3 0 0 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Ank PF00023.30 KXS16435.1 - 0.00088 19.6 1.3 0.016 15.6 0.1 3.1 3 1 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.7 KXS16435.1 - 0.0011 19.5 0.0 0.066 13.8 0.0 2.8 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXS16435.1 - 0.0011 19.3 1.6 0.03 14.9 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 KXS16435.1 - 0.015 15.6 0.0 0.1 12.9 0.0 2.4 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXS16435.1 - 0.023 15.3 0.4 5.5 7.7 0.0 3.2 3 0 0 3 3 3 0 Ankyrin repeats (many copies) TPPK_C PF12555.8 KXS16436.1 - 1.7 8.8 8.0 4.2 7.5 0.2 2.6 3 0 0 3 3 3 0 Thiamine pyrophosphokinase C terminal AzlD PF05437.12 KXS16438.1 - 0.074 13.2 5.2 1.8 8.8 0.2 2.4 2 0 0 2 2 2 0 Branched-chain amino acid transport protein (AzlD) SKG6 PF08693.10 KXS16438.1 - 6 6.4 11.1 0.15 11.5 3.3 2.2 2 0 0 2 2 2 0 Transmembrane alpha-helix domain WD40 PF00400.32 KXS16439.1 - 0.11 13.4 0.1 23 6.1 0.0 3.1 3 0 0 3 3 3 0 WD domain, G-beta repeat AAA PF00004.29 KXS16440.1 - 6.8e-15 55.7 0.0 2e-07 31.5 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) BCS1_N PF08740.11 KXS16440.1 - 2.8e-10 40.5 0.9 4.9e-10 39.7 0.9 1.4 1 0 0 1 1 1 1 BCS1 N terminal AAA_16 PF13191.6 KXS16440.1 - 0.00015 22.2 0.0 0.00071 20.0 0.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_11 PF13086.6 KXS16440.1 - 0.025 14.3 0.0 0.05 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 KXS16440.1 - 0.043 13.2 0.0 0.07 12.5 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_22 PF13401.6 KXS16440.1 - 0.049 13.9 0.1 1 9.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KXS16440.1 - 0.091 12.3 0.0 0.28 10.7 0.0 1.8 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_5 PF07728.14 KXS16440.1 - 0.11 12.5 0.0 0.27 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF815 PF05673.13 KXS16440.1 - 0.13 11.4 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) MMR_HSR1 PF01926.23 KXS16440.1 - 0.14 12.2 0.0 0.3 11.2 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_33 PF13671.6 KXS16440.1 - 0.18 11.9 0.6 0.35 11.0 0.1 1.7 2 0 0 2 2 2 0 AAA domain BCS1_N PF08740.11 KXS16441.1 - 5.6e-12 46.0 0.0 8.5e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 BCS1 N terminal CHB_HEX_C_1 PF13290.6 KXS16441.1 - 0.014 15.4 0.0 0.025 14.6 0.0 1.4 1 0 0 1 1 1 0 Chitobiase/beta-hexosaminidase C-terminal domain PTS_EIIC PF02378.18 KXS16441.1 - 0.072 12.1 0.1 0.11 11.5 0.1 1.2 1 0 0 1 1 1 0 Phosphotransferase system, EIIC RPGR1_C PF18111.1 KXS16441.1 - 0.19 11.6 0.0 0.28 11.1 0.0 1.1 1 0 0 1 1 1 0 Retinitis pigmentosa G-protein regulator interacting C-terminal adh_short_C2 PF13561.6 KXS16442.1 - 5e-60 203.0 0.1 5.9e-60 202.7 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXS16442.1 - 6.2e-43 146.5 0.1 7.8e-43 146.2 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXS16442.1 - 4e-13 49.7 0.1 6.4e-13 49.0 0.1 1.2 1 0 0 1 1 1 1 KR domain YbjQ_1 PF01906.17 KXS16443.1 - 1.9e-27 95.9 0.6 2.2e-27 95.7 0.6 1.0 1 0 0 1 1 1 1 Putative heavy-metal-binding Beta-prism_lec PF16458.5 KXS16443.1 - 0.051 13.5 0.0 0.064 13.2 0.0 1.2 1 0 0 1 1 1 0 Beta-prism lectin BatD PF13584.6 KXS16448.1 - 0.006 15.4 0.1 0.0083 15.0 0.1 1.1 1 0 0 1 1 1 1 Oxygen tolerance COX6C PF02937.15 KXS16448.1 - 0.027 14.6 0.1 0.059 13.5 0.1 1.6 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIc Amnionless PF14828.6 KXS16448.1 - 0.028 13.3 0.0 0.046 12.6 0.0 1.3 1 0 0 1 1 1 0 Amnionless DUF1180 PF06679.12 KXS16448.1 - 0.046 14.1 14.3 0.14 12.6 14.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) OSTbeta PF15048.6 KXS16448.1 - 0.094 12.9 0.0 2.7 8.1 0.0 2.2 2 0 0 2 2 2 0 Organic solute transporter subunit beta protein LapA_dom PF06305.11 KXS16448.1 - 0.12 12.2 0.1 0.22 11.4 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain DUF2681 PF10883.8 KXS16448.1 - 0.13 12.7 1.0 2.7 8.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) SOG2 PF10428.9 KXS16448.1 - 0.28 10.4 8.6 0.37 9.9 8.6 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Peptidase_M56 PF05569.11 KXS16448.1 - 0.28 10.3 0.0 0.4 9.8 0.0 1.2 1 0 0 1 1 1 0 BlaR1 peptidase M56 Hamartin PF04388.12 KXS16448.1 - 0.61 8.7 3.0 0.68 8.5 3.0 1.1 1 0 0 1 1 1 0 Hamartin protein SpoIIM PF01944.17 KXS16452.1 - 0.06 13.4 3.0 0.083 12.9 3.0 1.2 1 0 0 1 1 1 0 Stage II sporulation protein M Chordopox_A33R PF05966.12 KXS16453.1 - 0.088 12.1 0.4 0.23 10.7 0.1 1.8 2 0 0 2 2 2 0 Chordopoxvirus A33R protein EphA2_TM PF14575.6 KXS16454.1 - 0.1 13.5 0.7 1.9 9.4 0.0 3.3 4 0 0 4 4 4 0 Ephrin type-A receptor 2 transmembrane domain SH3_9 PF14604.6 KXS16455.1 - 0.005 16.7 0.0 0.021 14.7 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain F_bP_aldolase PF01116.20 KXS16456.1 - 4.8e-95 318.2 0.0 5.4e-95 318.1 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II ABC_sub_bind PF04392.12 KXS16456.1 - 0.13 11.5 0.2 3.9 6.6 0.1 2.3 2 1 0 2 2 2 0 ABC transporter substrate binding protein Hpr_kinase_N PF02603.16 KXS16456.1 - 0.16 12.0 0.0 2 8.4 0.0 2.2 2 0 0 2 2 2 0 HPr Serine kinase N terminus MFS_1 PF07690.16 KXS16459.1 - 2.6e-07 29.9 6.2 3.5e-07 29.5 0.5 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily DDE_Tnp_4 PF13359.6 KXS16461.1 - 7.3e-18 64.7 0.0 9.4e-18 64.4 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 KXS16461.1 - 0.0081 15.8 0.0 0.012 15.3 0.0 1.2 1 0 0 1 1 1 1 Transposase DDE domain DDE_3 PF13358.6 KXS16462.1 - 9.7e-05 22.1 0.0 0.00011 22.0 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease Seadorna_VP7 PF07387.11 KXS16464.1 - 0.06 12.4 0.0 0.078 12.0 0.0 1.0 1 0 0 1 1 1 0 Seadornavirus VP7 BIV_Env PF05858.12 KXS16465.1 - 0.042 12.0 0.0 0.052 11.7 0.0 1.1 1 0 0 1 1 1 0 Bovine immunodeficiency virus surface protein (SU) SH3_1 PF00018.28 KXS16465.1 - 0.076 12.6 0.0 0.22 11.2 0.0 1.7 2 0 0 2 2 2 0 SH3 domain MAGI_u5 PF16666.5 KXS16465.1 - 1.3 9.2 5.7 8.2 6.6 5.7 2.1 1 1 0 1 1 1 0 Unstructured region on MAGI CABS1 PF15367.6 KXS16466.1 - 0.24 10.5 0.1 0.28 10.3 0.1 1.1 1 0 0 1 1 1 0 Calcium-binding and spermatid-specific protein 1 LRR_8 PF13855.6 KXS16467.1 - 1.5e-08 34.3 0.1 3.1e-08 33.3 0.1 1.5 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 KXS16467.1 - 4.5e-05 23.7 0.2 4.5e-05 23.7 0.2 2.2 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) SH3_9 PF14604.6 KXS16467.1 - 0.0054 16.6 0.1 0.01 15.6 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXS16467.1 - 0.0063 16.1 0.0 0.015 14.9 0.0 1.7 1 0 0 1 1 1 1 SH3 domain Yip1 PF04893.17 KXS16467.1 - 0.045 13.5 0.1 0.045 13.5 0.1 1.7 2 0 0 2 2 2 0 Yip1 domain AJAP1_PANP_C PF15298.6 KXS16467.1 - 0.06 13.5 7.9 0.11 12.7 7.9 1.4 1 0 0 1 1 1 0 AJAP1/PANP C-terminus Syndecan PF01034.20 KXS16467.1 - 0.13 12.2 0.3 0.26 11.2 0.3 1.4 1 0 0 1 1 1 0 Syndecan domain LRR_1 PF00560.33 KXS16467.1 - 0.25 12.0 2.1 14 6.7 0.0 3.6 3 1 0 3 3 3 0 Leucine Rich Repeat Sel1 PF08238.12 KXS16468.1 - 0.00075 20.1 0.0 0.0027 18.3 0.0 2.0 1 0 0 1 1 1 1 Sel1 repeat DUF4229 PF14012.6 KXS16468.1 - 0.094 12.8 1.1 0.17 12.0 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4229) DUF702 PF05142.12 KXS16468.1 - 0.097 13.2 1.4 0.31 11.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF702) Ogr_Delta PF04606.12 KXS16469.1 - 0.052 13.5 6.7 1.7 8.7 2.2 2.7 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger GATA PF00320.27 KXS16469.1 - 0.46 10.1 8.6 0.099 12.3 4.4 2.1 2 0 0 2 2 2 0 GATA zinc finger Pertussis_S1 PF02917.14 KXS16470.1 - 1.4 8.6 7.7 2.2 8.0 7.7 1.2 1 0 0 1 1 1 0 Pertussis toxin, subunit 1 FeS_assembly_P PF01883.19 KXS16471.1 - 7.8e-08 32.4 0.1 5.5e-07 29.7 0.1 2.3 1 1 0 1 1 1 1 Iron-sulfur cluster assembly protein AMP-binding PF00501.28 KXS16472.1 - 8.7e-84 281.6 0.0 1.1e-83 281.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXS16472.1 - 1.4e-16 61.2 1.5 2.9e-16 60.2 1.5 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ABC_membrane PF00664.23 KXS16473.1 - 6e-70 236.0 30.5 9.4e-38 130.4 8.5 2.5 3 0 0 3 3 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KXS16473.1 - 4.5e-53 179.4 0.0 6.3e-29 101.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KXS16473.1 - 1.8e-08 34.1 2.6 0.03 13.8 0.0 4.2 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KXS16473.1 - 4.7e-07 29.9 0.4 0.0032 17.5 0.1 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 KXS16473.1 - 6.6e-06 25.8 0.2 0.055 13.2 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KXS16473.1 - 9.4e-06 25.6 0.0 0.0022 17.9 0.0 2.6 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 KXS16473.1 - 2.3e-05 24.9 1.7 0.17 12.3 0.2 2.7 2 1 0 2 2 2 2 AAA ATPase domain Dynamin_N PF00350.23 KXS16473.1 - 0.00022 21.3 5.0 0.0013 18.8 0.7 2.4 2 0 0 2 2 2 1 Dynamin family DUF815 PF05673.13 KXS16473.1 - 0.00036 19.8 0.1 0.37 9.9 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF815) Zeta_toxin PF06414.12 KXS16473.1 - 0.00049 19.4 0.5 0.039 13.2 0.1 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_21 PF13304.6 KXS16473.1 - 0.00063 19.6 0.7 1.6 8.5 0.1 3.4 4 0 0 4 4 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_7 PF12775.7 KXS16473.1 - 0.00096 18.7 0.0 0.1 12.1 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region T2SSE PF00437.20 KXS16473.1 - 0.0015 17.6 0.0 0.25 10.4 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein DUF87 PF01935.17 KXS16473.1 - 0.0024 18.0 0.9 1.2 9.2 0.0 2.5 2 0 0 2 2 2 1 Helicase HerA, central domain TrwB_AAD_bind PF10412.9 KXS16473.1 - 0.0062 15.5 0.1 2.8 6.7 0.0 2.2 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain AAA_23 PF13476.6 KXS16473.1 - 0.011 16.2 0.3 2.4 8.6 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KXS16473.1 - 0.027 14.7 2.9 10 6.4 0.0 3.8 3 1 0 3 3 3 0 AAA domain Roc PF08477.13 KXS16473.1 - 0.037 14.3 0.2 12 6.2 0.0 2.9 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_30 PF13604.6 KXS16473.1 - 0.042 13.6 1.0 1.5 8.5 0.1 2.8 2 1 0 2 2 2 0 AAA domain AIG1 PF04548.16 KXS16473.1 - 0.043 13.1 1.9 1.3 8.3 0.1 2.6 2 0 0 2 2 2 0 AIG1 family CDC45 PF02724.14 KXS16473.1 - 0.049 11.9 0.0 0.071 11.4 0.0 1.1 1 0 0 1 1 1 0 CDC45-like protein IstB_IS21 PF01695.17 KXS16473.1 - 0.054 13.2 1.3 4.3 7.0 0.0 2.9 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_25 PF13481.6 KXS16473.1 - 0.06 12.9 0.3 7.6 6.0 0.1 2.6 2 0 0 2 2 2 0 AAA domain VirE PF05272.11 KXS16473.1 - 0.086 12.6 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Virulence-associated protein E AAA PF00004.29 KXS16473.1 - 0.11 13.0 0.1 21 5.5 0.0 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 KXS16473.1 - 0.13 11.8 0.5 0.67 9.5 0.1 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 KXS16473.1 - 0.16 10.9 0.4 10 5.0 0.0 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NTP_transf_2 PF01909.23 KXS16474.1 - 2.1e-06 27.9 0.0 7.3e-06 26.2 0.0 1.9 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 KXS16474.1 - 0.017 15.2 0.1 0.04 14.0 0.1 1.5 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase zf-CCCH PF00642.24 KXS16474.1 - 0.068 13.1 3.7 0.16 11.9 3.7 1.6 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KXS16474.1 - 0.98 9.6 10.7 0.17 11.9 6.9 1.8 2 0 0 2 2 2 0 Zinc finger domain Asp-B-Hydro_N PF05279.11 KXS16474.1 - 5.8 6.9 23.0 13 5.7 23.0 1.6 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region zf-CCCH_4 PF18044.1 KXS16474.1 - 7.2 6.5 8.8 1.1 9.1 4.9 1.7 2 0 0 2 2 2 0 CCCH-type zinc finger TPR_1 PF00515.28 KXS16475.1 - 5.6e-09 35.5 0.0 1.4e-05 24.7 0.0 2.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KXS16475.1 - 2.5e-08 33.4 0.0 0.0011 18.9 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 KXS16475.1 - 0.00016 21.5 1.2 0.013 15.5 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 KXS16475.1 - 0.00055 19.9 0.0 0.023 14.9 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 KXS16475.1 - 0.0011 19.2 0.0 0.037 14.3 0.1 2.7 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 KXS16475.1 - 0.0034 17.9 0.1 0.19 12.3 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 KXS16475.1 - 0.032 14.6 0.0 12 6.5 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KXS16475.1 - 0.082 13.2 0.0 0.76 10.0 0.0 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Abhydrolase_3 PF07859.13 KXS16475.1 - 0.1 12.4 0.3 0.26 11.1 0.1 1.7 1 1 0 1 1 1 0 alpha/beta hydrolase fold TPR_6 PF13174.6 KXS16475.1 - 0.14 12.9 0.2 35 5.3 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 KXS16475.1 - 0.2 12.3 9.0 1.1 10.0 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 KXS16475.1 - 0.21 12.5 8.3 0.5 11.3 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat F-box PF00646.33 KXS16476.1 - 0.001 18.9 2.7 0.001 18.9 0.6 2.1 2 0 0 2 2 2 1 F-box domain CAP PF00188.26 KXS16477.1 - 4.8e-07 30.7 0.0 8e-06 26.7 0.0 2.1 2 0 0 2 2 2 1 Cysteine-rich secretory protein family APH PF01636.23 KXS16478.1 - 3.1e-22 79.7 0.0 4e-22 79.3 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Tau95_N PF17682.1 KXS16479.1 - 1.1e-25 90.2 0.0 4.1e-25 88.4 0.0 2.0 2 0 0 2 2 2 1 Tau95 Triple barrel domain Tau95 PF09734.9 KXS16479.1 - 4.4e-20 72.9 0.1 1e-19 71.7 0.1 1.7 1 1 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain G_glu_transpept PF01019.21 KXS16480.1 - 3.5e-137 458.3 0.0 4e-137 458.1 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase FBA_1 PF07734.13 KXS16481.1 - 0.072 13.0 0.6 0.13 12.1 0.6 1.4 1 0 0 1 1 1 0 F-box associated ParA PF10609.9 KXS16482.1 - 1.1e-86 290.3 0.0 1.9e-86 289.6 0.0 1.3 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KXS16482.1 - 4.9e-11 42.8 0.0 9.3e-11 41.9 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 KXS16482.1 - 1e-06 28.8 1.2 1.8e-05 24.7 1.2 2.1 1 1 0 1 1 1 1 AAA domain MipZ PF09140.11 KXS16482.1 - 1.8e-06 27.4 0.0 4.5e-06 26.1 0.0 1.6 1 1 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.15 KXS16482.1 - 3.1e-05 23.3 0.4 6.1e-05 22.4 0.4 1.4 1 0 0 1 1 1 1 Anion-transporting ATPase CBP_BcsQ PF06564.12 KXS16482.1 - 0.00063 19.3 0.0 0.0015 18.0 0.0 1.5 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ AAA_26 PF13500.6 KXS16482.1 - 0.0023 17.8 0.5 2 8.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 KXS16482.1 - 0.0026 17.4 0.0 0.0045 16.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain MeaB PF03308.16 KXS16482.1 - 0.0062 15.6 0.2 0.011 14.8 0.2 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Fer4_NifH PF00142.18 KXS16482.1 - 0.0064 16.0 0.3 0.048 13.1 0.1 2.3 3 0 0 3 3 3 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family APS_kinase PF01583.20 KXS16482.1 - 0.037 13.9 0.0 0.058 13.3 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_16 PF13191.6 KXS16482.1 - 0.06 13.7 0.0 0.1 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 KXS16482.1 - 0.068 13.1 0.3 0.13 12.2 0.3 1.4 1 0 0 1 1 1 0 RsgA GTPase SRP54 PF00448.22 KXS16482.1 - 0.12 12.0 0.2 0.25 11.0 0.2 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain RNA_helicase PF00910.22 KXS16482.1 - 0.12 12.7 0.1 0.31 11.4 0.1 1.6 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.12 KXS16482.1 - 0.27 11.1 0.4 0.5 10.3 0.4 1.4 1 0 0 1 1 1 0 NACHT domain MEA1 PF06910.11 KXS16484.1 - 0.00012 22.7 4.3 0.00034 21.2 0.5 2.7 3 0 0 3 3 3 1 Male enhanced antigen 1 (MEA1) adh_short_C2 PF13561.6 KXS16485.1 - 3.1e-05 23.7 0.0 3.4e-05 23.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXS16485.1 - 0.00032 20.2 0.0 0.00048 19.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Formyl_trans_N PF00551.19 KXS16486.1 - 1.8e-45 154.9 0.0 2.1e-45 154.7 0.0 1.0 1 0 0 1 1 1 1 Formyl transferase SnoaL_2 PF12680.7 KXS16486.1 - 0.062 14.0 0.0 0.1 13.2 0.0 1.4 1 0 0 1 1 1 0 SnoaL-like domain RST PF12174.8 KXS16486.1 - 0.11 12.5 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 RCD1-SRO-TAF4 (RST) plant domain Ank_2 PF12796.7 KXS16488.1 - 1.5e-14 54.4 0.0 0.17 12.5 0.0 5.6 3 1 0 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXS16488.1 - 1.5e-08 35.0 3.1 0.072 13.7 0.1 5.4 6 1 0 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXS16488.1 - 7e-08 32.2 1.2 11 7.0 0.0 7.6 9 0 0 9 9 9 2 Ankyrin repeat Ank_5 PF13857.6 KXS16488.1 - 1.1e-05 25.6 0.1 1.4 9.3 0.0 5.2 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank PF00023.30 KXS16488.1 - 0.00098 19.5 0.7 14 6.3 0.0 5.6 7 0 0 7 7 7 1 Ankyrin repeat RBD-FIP PF09457.10 KXS16489.1 - 0.23 11.4 0.0 0.46 10.4 0.0 1.5 1 0 0 1 1 1 0 FIP domain zf-CCHC_2 PF13696.6 KXS16490.1 - 2.1e-26 91.3 23.8 8.9e-11 41.4 6.6 3.4 3 0 0 3 3 3 3 Zinc knuckle zf-CCHC PF00098.23 KXS16490.1 - 5.4e-05 23.1 8.8 0.0028 17.6 0.2 3.4 3 0 0 3 3 3 2 Zinc knuckle zf-CCHC_4 PF14392.6 KXS16490.1 - 0.0018 18.0 14.9 0.44 10.3 0.2 3.4 3 0 0 3 3 3 3 Zinc knuckle zf-CCHC_3 PF13917.6 KXS16490.1 - 0.014 15.3 8.7 0.18 11.8 0.3 3.4 3 0 0 3 3 3 0 Zinc knuckle CBP_BcsN PF17038.5 KXS16490.1 - 0.16 11.3 1.4 1.2 8.5 0.2 2.2 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsN DUF4428 PF14471.6 KXS16490.1 - 1.8 8.6 5.2 45 4.1 0.3 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4428) eIF3g PF12353.8 KXS16490.1 - 3.7 8.0 10.7 0.81 10.1 0.3 3.7 4 0 0 4 4 4 0 Eukaryotic translation initiation factor 3 subunit G E1-E2_ATPase PF00122.20 KXS16491.1 - 6.5e-37 126.8 0.2 1.6e-36 125.5 0.2 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KXS16491.1 - 5.4e-20 71.9 1.7 1.2e-19 70.7 0.2 2.2 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KXS16491.1 - 2.5e-18 67.1 10.3 2.4e-17 63.9 10.3 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KXS16491.1 - 6.8e-12 44.9 0.4 2.2e-11 43.3 0.0 2.1 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KXS16491.1 - 0.0048 16.7 0.2 0.51 10.0 0.2 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KXS16491.1 - 0.0097 16.0 0.0 0.019 15.0 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Acyltransferase PF01553.21 KXS16493.1 - 0.037 13.7 0.6 0.27 10.9 0.6 2.0 1 1 0 1 1 1 0 Acyltransferase Phage_P2_GpE PF06528.12 KXS16493.1 - 0.2 11.2 0.5 0.55 9.8 0.0 2.0 2 0 0 2 2 2 0 Phage P2 GpE 4HBT_3 PF13622.6 KXS16494.1 - 3.1e-25 89.9 0.1 4.1e-25 89.5 0.1 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 KXS16494.1 - 0.021 15.2 0.2 0.52 10.7 0.0 2.8 3 0 0 3 3 3 0 Thioesterase superfamily Bac_rhodopsin PF01036.18 KXS16496.1 - 3.5e-49 167.4 18.9 4e-49 167.2 18.9 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein zf-MYND PF01753.18 KXS16497.1 - 1.6e-05 24.9 5.6 3.3e-05 23.9 5.6 1.5 1 0 0 1 1 1 1 MYND finger Sec3_C PF09763.9 KXS16497.1 - 0.028 12.8 0.0 0.035 12.5 0.0 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec3 zf-LYAR PF08790.11 KXS16498.1 - 1.7e-15 56.6 1.1 2.7e-15 56.0 0.2 1.7 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger zf-C2H2_4 PF13894.6 KXS16498.1 - 0.052 14.4 0.6 0.17 12.8 0.1 2.0 2 0 0 2 2 2 0 C2H2-type zinc finger Ribosomal_L38e PF01781.18 KXS16499.1 - 7.4e-31 106.1 0.3 8.1e-31 105.9 0.3 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family SLAC1 PF03595.17 KXS16500.1 - 0.047 13.0 1.2 0.087 12.1 0.7 1.4 1 1 0 1 1 1 0 Voltage-dependent anion channel DMA PF03474.14 KXS16501.1 - 0.096 12.3 0.7 20 4.8 0.0 3.0 3 0 0 3 3 3 0 DMRTA motif Pkinase PF00069.25 KXS16504.1 - 3.2e-65 220.1 0.0 3.9e-65 219.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS16504.1 - 1.6e-43 148.9 0.0 2e-43 148.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXS16504.1 - 1.7e-05 23.8 0.0 2.5e-05 23.2 0.0 1.4 1 1 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KXS16504.1 - 8.6e-05 22.0 0.0 0.00026 20.4 0.0 1.8 2 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 KXS16504.1 - 9.4e-05 21.5 0.0 0.0002 20.5 0.0 1.4 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KXS16504.1 - 0.00069 19.0 0.0 0.0011 18.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF309 PF03745.14 KXS16504.1 - 0.16 11.6 0.1 0.3 10.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF309) WD40 PF00400.32 KXS16505.1 - 4e-08 33.8 11.4 2.7 9.0 0.1 5.7 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXS16505.1 - 0.0083 16.4 0.0 0.77 10.1 0.0 3.2 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain RGS PF00615.19 KXS16506.1 - 5.6e-13 49.2 0.0 2.3e-11 44.0 0.0 2.5 2 0 0 2 2 2 2 Regulator of G protein signaling domain Ribosomal_L5 PF00281.19 KXS16507.1 - 0.041 14.2 0.0 1.8 9.0 0.0 2.5 2 0 0 2 2 2 0 Ribosomal protein L5 DUF1295 PF06966.12 KXS16508.1 - 1.5e-49 168.6 4.5 1.8e-49 168.4 4.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.16 KXS16508.1 - 6.9e-05 22.9 1.6 0.00015 21.8 1.6 1.7 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.13 KXS16508.1 - 7.5e-05 23.1 0.5 7.5e-05 23.1 0.5 2.0 2 0 0 2 2 2 1 Phospholipid methyltransferase ICMT PF04140.14 KXS16508.1 - 0.00071 20.0 0.6 0.0051 17.2 0.6 2.4 2 1 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family TPR_10 PF13374.6 KXS16509.1 - 6.4e-105 340.6 59.0 4.5e-10 39.1 0.0 14.9 15 0 0 15 15 15 14 Tetratricopeptide repeat TPR_12 PF13424.6 KXS16509.1 - 9.3e-96 314.2 68.6 1.1e-13 51.2 0.3 10.4 2 1 9 13 13 13 12 Tetratricopeptide repeat TPR_8 PF13181.6 KXS16509.1 - 3.6e-25 86.0 7.4 0.63 10.4 0.0 13.5 14 0 0 14 14 14 3 Tetratricopeptide repeat TPR_6 PF13174.6 KXS16509.1 - 4.2e-22 77.2 21.9 0.26 12.0 0.2 13.4 13 0 0 13 13 13 5 Tetratricopeptide repeat TPR_2 PF07719.17 KXS16509.1 - 4.4e-22 76.4 26.8 0.56 10.4 0.0 13.8 14 0 0 14 14 14 5 Tetratricopeptide repeat TPR_14 PF13428.6 KXS16509.1 - 7.2e-22 76.2 46.3 0.03 15.1 0.1 14.0 10 4 5 15 15 13 7 Tetratricopeptide repeat TPR_19 PF14559.6 KXS16509.1 - 4.2e-21 75.2 35.3 0.0075 16.8 0.1 11.3 4 3 9 13 13 12 8 Tetratricopeptide repeat TPR_7 PF13176.6 KXS16509.1 - 1.5e-20 71.6 33.3 0.03 14.3 0.1 13.8 14 0 0 14 14 14 6 Tetratricopeptide repeat TPR_1 PF00515.28 KXS16509.1 - 2.3e-20 71.5 21.8 0.26 11.2 0.0 12.5 14 0 0 14 14 14 6 Tetratricopeptide repeat ANAPC3 PF12895.7 KXS16509.1 - 2.3e-20 72.6 5.6 0.08 13.2 0.0 10.0 4 1 6 11 11 11 6 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.14 KXS16509.1 - 2.4e-17 61.7 42.7 0.12 13.0 0.4 12.9 12 0 0 12 12 12 6 Tetratricopeptide repeat TPR_MalT PF17874.1 KXS16509.1 - 2.5e-14 53.4 42.7 1.9e-07 30.8 22.6 4.6 1 1 4 5 5 5 4 MalT-like TPR region PPR PF01535.20 KXS16509.1 - 2.9e-14 52.2 1.7 0.36 11.2 0.0 11.5 12 0 0 12 12 12 1 PPR repeat TPR_16 PF13432.6 KXS16509.1 - 2.9e-14 53.4 47.0 0.00042 20.9 0.9 10.7 7 3 4 11 11 11 6 Tetratricopeptide repeat TPR_20 PF14561.6 KXS16509.1 - 3.8e-12 46.4 37.1 0.25 11.7 0.1 12.4 1 1 12 13 13 13 3 Tetratricopeptide repeat Pkinase_Tyr PF07714.17 KXS16509.1 - 1.4e-11 44.2 0.0 3.2e-11 43.0 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase Sel1 PF08238.12 KXS16509.1 - 1.4e-08 35.1 17.4 6.1e-06 26.7 3.5 7.1 8 0 0 8 8 5 2 Sel1 repeat Pkinase PF00069.25 KXS16509.1 - 6.4e-08 32.3 0.0 2.6e-07 30.3 0.0 2.1 1 0 0 1 1 1 1 Protein kinase domain RPN7 PF10602.9 KXS16509.1 - 3.9e-07 29.9 1.0 1.7 8.3 0.0 6.3 2 1 3 7 7 7 1 26S proteasome subunit RPN7 PilO PF04350.13 KXS16509.1 - 5.7e-07 29.8 2.1 2.4 8.3 0.0 7.1 3 2 5 8 8 8 1 Pilus assembly protein, PilO ATG16 PF08614.11 KXS16509.1 - 0.00064 20.0 23.6 0.96 9.6 1.7 7.1 1 1 4 7 7 7 1 Autophagy protein 16 (ATG16) TPR_17 PF13431.6 KXS16509.1 - 0.00073 19.8 29.5 5 7.7 0.1 10.7 11 0 0 11 11 11 1 Tetratricopeptide repeat DUF2977 PF11192.8 KXS16509.1 - 0.011 15.8 0.0 16 5.7 0.0 5.0 5 0 0 5 5 5 0 Protein of unknown function (DUF2977) PPR_1 PF12854.7 KXS16509.1 - 0.045 13.4 14.4 1.2e+02 2.5 0.1 9.6 12 0 0 12 12 12 0 PPR repeat Glyco_hydro_115 PF15979.5 KXS16509.1 - 0.11 11.9 0.2 38 3.6 0.1 4.2 4 0 0 4 4 4 0 Glycosyl hydrolase family 115 TPR_9 PF13371.6 KXS16509.1 - 0.22 11.7 33.3 3.4 7.9 0.8 9.0 5 2 6 11 11 11 0 Tetratricopeptide repeat RPN6_N PF18055.1 KXS16509.1 - 0.64 10.4 6.5 18 5.7 0.0 4.9 4 2 2 6 6 6 0 26S proteasome regulatory subunit RPN6 N-terminal domain TPR_3 PF07720.12 KXS16509.1 - 0.64 10.1 10.2 23 5.1 0.1 5.6 6 0 0 6 6 5 0 Tetratricopeptide repeat DUF3301 PF11743.8 KXS16509.1 - 8.9 6.1 10.0 18 5.1 0.1 5.1 4 1 1 5 5 4 0 Protein of unknown function (DUF3301) Methyltransf_22 PF13383.6 KXS16510.1 - 0.1 12.2 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DUF4407 PF14362.6 KXS16510.1 - 0.31 10.4 23.0 2.8 7.2 9.3 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF1664 PF07889.12 KXS16510.1 - 1.4 8.9 20.8 0.53 10.3 0.3 4.1 3 2 0 3 3 3 0 Protein of unknown function (DUF1664) NPV_P10 PF05531.12 KXS16510.1 - 4.6 7.8 5.2 14 6.3 0.4 3.7 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein OmpH PF03938.14 KXS16510.1 - 5.3 7.4 39.7 5.1 7.4 1.5 3.5 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) Spectrin PF00435.21 KXS16510.1 - 6 7.4 38.3 0.092 13.2 3.5 5.4 3 3 1 5 5 5 0 Spectrin repeat FAD-SLDH PF12318.8 KXS16510.1 - 7.8 6.5 6.1 4.5 7.3 2.0 2.4 2 0 0 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase BCDHK_Adom3 PF10436.9 KXS16511.1 - 3e-38 131.2 0.0 4.1e-38 130.8 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KXS16511.1 - 6.7e-09 36.2 0.0 2.6e-07 31.1 0.0 2.2 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KXS16511.1 - 2.2e-05 24.3 0.0 3.4e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SBF PF01758.16 KXS16512.1 - 5.6e-25 88.2 12.5 3e-22 79.3 12.0 2.8 1 1 0 1 1 1 1 Sodium Bile acid symporter family Hydrolase PF00702.26 KXS16513.1 - 8.3e-05 23.0 0.1 0.002 18.5 0.1 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KXS16513.1 - 0.023 14.8 0.0 0.043 13.9 0.0 1.5 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Sin3a_C PF16879.5 KXS16514.1 - 6.8e-61 206.5 1.1 6.8e-61 206.5 1.1 2.7 4 0 0 4 4 4 1 C-terminal domain of Sin3a protein PAH PF02671.21 KXS16514.1 - 3.9e-41 138.9 7.6 4.3e-17 62.0 5.0 4.6 4 0 0 4 4 4 3 Paired amphipathic helix repeat Sin3_corepress PF08295.12 KXS16514.1 - 4e-31 107.0 0.2 9.5e-31 105.8 0.2 1.7 1 0 0 1 1 1 1 Sin3 family co-repressor CDC24_OB1 PF17246.2 KXS16514.1 - 0.017 15.3 0.2 0.038 14.1 0.2 1.6 1 0 0 1 1 1 0 Cell division control protein 24, OB domain 1 zf-PARP PF00645.18 KXS16515.1 - 1.5e-05 25.7 0.1 3e-05 24.8 0.1 1.5 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region DTHCT PF08070.11 KXS16515.1 - 0.11 13.3 9.7 0.19 12.5 9.7 1.4 1 0 0 1 1 1 0 DTHCT (NUC029) region CAP_N PF01213.19 KXS16515.1 - 0.11 11.9 2.0 0.15 11.5 2.0 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal RTA1 PF04479.13 KXS16516.1 - 3.3e-51 173.8 10.8 3.3e-51 173.8 10.8 1.8 1 1 1 2 2 2 1 RTA1 like protein DUF3098 PF11297.8 KXS16516.1 - 0.034 13.7 5.5 0.056 13.0 0.3 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3098) DUF373 PF04123.13 KXS16516.1 - 0.19 11.1 12.9 0.36 10.2 12.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF373) HlyIII PF03006.20 KXS16516.1 - 0.39 10.4 14.6 0.087 12.5 4.2 2.1 1 1 0 2 2 2 0 Haemolysin-III related Saf_2TM PF18303.1 KXS16516.1 - 1.8 8.1 9.3 0.83 9.2 1.1 2.3 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain Aldedh PF00171.22 KXS16517.1 - 1e-98 330.8 0.0 1.3e-98 330.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family NAD_binding_10 PF13460.6 KXS16519.1 - 2.1e-13 50.6 0.1 2.5e-13 50.3 0.1 1.1 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KXS16519.1 - 7.1e-08 32.3 0.3 8.8e-08 32.0 0.3 1.1 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 KXS16519.1 - 8.5e-05 21.7 0.1 0.00011 21.4 0.1 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 KXS16519.1 - 0.0011 18.4 0.1 0.0014 18.1 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 KXS16519.1 - 0.0022 17.5 0.0 0.0026 17.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 KXS16519.1 - 0.0058 16.9 0.0 0.0071 16.6 0.0 1.1 1 0 0 1 1 1 1 TrkA-N domain KR PF08659.10 KXS16519.1 - 0.0096 15.9 0.5 0.013 15.4 0.1 1.5 2 0 0 2 2 2 1 KR domain Semialdhyde_dh PF01118.24 KXS16519.1 - 0.017 15.5 0.1 0.023 15.1 0.1 1.2 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 KXS16519.1 - 0.036 13.2 0.0 0.048 12.8 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein GCD14 PF08704.10 KXS16519.1 - 0.16 11.6 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit WD40 PF00400.32 KXS16521.1 - 0.00039 21.2 0.1 0.76 10.7 0.0 3.5 3 0 0 3 3 3 2 WD domain, G-beta repeat FAD_binding_4 PF01565.23 KXS16522.1 - 6.2e-24 84.3 0.1 1.1e-22 80.2 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain ALO PF04030.14 KXS16522.1 - 6.7e-10 39.2 0.1 1.1e-05 25.4 0.1 3.4 3 1 0 3 3 3 3 D-arabinono-1,4-lactone oxidase Kinesin PF00225.23 KXS16523.1 - 1.8e-21 76.5 0.4 1.9e-17 63.2 0.3 3.2 2 1 0 2 2 2 2 Kinesin motor domain DHR10 PF18595.1 KXS16523.1 - 0.0003 20.8 19.1 0.0003 20.8 19.1 3.9 2 1 1 3 3 3 1 Designed helical repeat protein 10 domain Med9 PF07544.13 KXS16523.1 - 0.0036 17.4 18.3 0.38 10.9 3.0 5.3 2 1 2 4 4 4 1 RNA polymerase II transcription mediator complex subunit 9 Fez1 PF06818.15 KXS16523.1 - 0.0098 16.4 28.6 3.5 8.0 5.2 3.4 1 1 1 2 2 2 1 Fez1 Tropomyosin PF00261.20 KXS16523.1 - 0.012 14.9 1.9 0.012 14.9 1.9 4.0 2 2 0 3 3 3 0 Tropomyosin Phage_GP20 PF06810.11 KXS16523.1 - 0.018 14.8 16.1 0.88 9.4 0.2 5.0 3 1 2 5 5 4 0 Phage minor structural protein GP20 FlaC_arch PF05377.11 KXS16523.1 - 0.029 14.8 13.8 14 6.1 0.9 7.1 6 1 1 7 7 6 0 Flagella accessory protein C (FlaC) DSBA PF01323.20 KXS16523.1 - 0.11 12.2 1.4 0.76 9.5 0.0 2.3 2 0 0 2 2 2 0 DSBA-like thioredoxin domain CENP-K PF11802.8 KXS16523.1 - 0.13 11.8 13.0 7.5 6.0 12.9 2.8 1 1 0 1 1 1 0 Centromere-associated protein K AAA_23 PF13476.6 KXS16523.1 - 0.25 11.8 7.6 0.89 10.0 4.9 2.4 2 0 0 2 2 2 0 AAA domain VSG_B PF13206.6 KXS16523.1 - 0.38 10.0 6.9 0.046 13.0 0.5 2.2 2 0 0 2 2 2 0 Trypanosomal VSG domain BST2 PF16716.5 KXS16523.1 - 0.4 11.3 32.9 0.23 12.0 0.2 4.8 5 1 1 6 6 5 0 Bone marrow stromal antigen 2 CENP-F_leu_zip PF10473.9 KXS16523.1 - 0.45 10.5 38.7 0.027 14.5 12.3 4.9 3 2 2 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SNARE PF05739.19 KXS16523.1 - 0.73 9.9 3.2 0.71 9.9 0.1 2.7 3 0 0 3 3 2 0 SNARE domain Prominin PF05478.11 KXS16523.1 - 0.9 7.4 10.3 0.092 10.7 5.1 1.8 2 0 0 2 2 2 0 Prominin HOOK PF05622.12 KXS16523.1 - 0.93 7.6 29.8 0.071 11.3 14.9 2.9 2 1 1 3 3 3 0 HOOK protein DivIC PF04977.15 KXS16523.1 - 1 9.2 24.7 26 4.7 0.0 7.0 5 2 2 7 7 7 0 Septum formation initiator Mito_fiss_reg PF05308.11 KXS16523.1 - 2.2 8.3 17.2 1.9 8.5 0.9 3.7 2 1 1 3 3 3 0 Mitochondrial fission regulator DUF948 PF06103.11 KXS16523.1 - 2.5 8.4 5.1 25 5.2 0.3 3.7 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) NPV_P10 PF05531.12 KXS16523.1 - 5.5 7.5 13.2 24 5.5 2.5 5.0 3 2 1 5 5 5 0 Nucleopolyhedrovirus P10 protein Macoilin PF09726.9 KXS16523.1 - 7 5.1 30.6 11 4.4 28.8 2.0 1 1 1 2 2 2 0 Macoilin family Cut12 PF11500.8 KXS16523.1 - 7.3 6.5 9.1 11 6.0 0.4 3.0 2 0 0 2 2 2 0 Spindle pole body formation-associated protein ATG16 PF08614.11 KXS16523.1 - 9.6 6.4 44.2 5.1 7.3 16.5 4.7 2 2 1 3 3 3 0 Autophagy protein 16 (ATG16) HALZ PF02183.18 KXS16524.1 - 0.031 14.5 0.1 0.069 13.4 0.1 1.6 1 0 0 1 1 1 0 Homeobox associated leucine zipper SH3_9 PF14604.6 KXS16527.1 - 5.2e-19 67.8 0.0 4.3e-08 32.9 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain Ank_2 PF12796.7 KXS16527.1 - 1.7e-15 57.4 2.2 0.0029 18.2 0.0 6.1 5 1 0 5 5 5 4 Ankyrin repeats (3 copies) SH3_1 PF00018.28 KXS16527.1 - 7e-15 54.4 0.0 4.6e-06 26.1 0.0 2.7 3 0 0 3 3 3 2 SH3 domain Ank_3 PF13606.6 KXS16527.1 - 8.6e-07 28.8 6.2 0.032 14.8 0.1 8.2 11 1 1 12 12 12 1 Ankyrin repeat Ank PF00023.30 KXS16527.1 - 1.2e-06 28.7 10.8 0.00087 19.6 0.2 7.6 9 1 0 9 9 9 1 Ankyrin repeat Ank_4 PF13637.6 KXS16527.1 - 2.1e-05 25.0 0.7 75 4.1 0.0 6.8 6 1 1 7 7 7 0 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXS16527.1 - 2.8e-05 24.3 3.5 11 6.5 0.1 6.2 7 0 0 7 7 7 1 Ankyrin repeats (many copies) SH3_2 PF07653.17 KXS16527.1 - 0.00096 18.8 0.0 0.48 10.1 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain adh_short PF00106.25 KXS16530.1 - 9.2e-29 100.3 0.0 4e-25 88.4 0.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXS16530.1 - 1.8e-15 57.2 0.1 2.3e-13 50.3 0.1 2.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXS16530.1 - 4.5e-08 33.2 0.1 6.3e-08 32.7 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXS16530.1 - 4.5e-07 29.6 0.0 2.5e-06 27.1 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KXS16530.1 - 0.0054 16.6 0.4 0.0091 15.9 0.4 1.3 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KXS16530.1 - 0.015 14.7 0.0 0.11 11.9 0.0 1.9 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase NmrA PF05368.13 KXS16530.1 - 0.093 12.3 1.0 0.15 11.6 0.3 1.6 2 0 0 2 2 2 0 NmrA-like family LDcluster4 PF18306.1 KXS16530.1 - 0.12 12.0 0.6 0.19 11.3 0.6 1.3 1 0 0 1 1 1 0 SLOG cluster4 family PPR_1 PF12854.7 KXS16531.1 - 0.0025 17.4 0.0 0.029 14.1 0.0 2.3 2 0 0 2 2 2 1 PPR repeat PPR_2 PF13041.6 KXS16531.1 - 0.0055 16.9 0.0 0.66 10.2 0.0 2.4 2 0 0 2 2 2 1 PPR repeat family Patatin PF01734.22 KXS16531.1 - 0.037 14.2 0.1 0.048 13.8 0.1 1.2 1 0 0 1 1 1 0 Patatin-like phospholipase PPR_3 PF13812.6 KXS16531.1 - 0.06 13.4 0.0 13 5.9 0.0 2.5 2 1 0 2 2 2 0 Pentatricopeptide repeat domain DIL PF01843.19 KXS16534.1 - 8.1e-17 61.4 0.1 1.4e-16 60.6 0.1 1.4 1 0 0 1 1 1 1 DIL domain Ank_2 PF12796.7 KXS16534.1 - 4.8e-11 43.1 0.5 2e-10 41.1 0.2 2.2 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXS16534.1 - 3.7e-08 33.8 0.0 2.7e-07 31.0 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 KXS16534.1 - 3.9e-06 27.1 0.1 0.0012 19.2 0.0 3.0 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 KXS16534.1 - 5e-06 26.7 0.3 0.069 13.5 0.0 3.1 2 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXS16534.1 - 0.003 17.9 0.0 0.51 11.1 0.0 3.6 3 0 0 3 3 3 1 Ankyrin repeat ACT_7 PF13840.6 KXS16535.1 - 8.6e-19 67.1 0.7 1.1e-18 66.8 0.7 1.2 1 0 0 1 1 1 1 ACT domain DUF2007 PF09413.10 KXS16535.1 - 0.048 13.8 0.2 0.17 12.1 0.2 1.9 1 1 0 1 1 1 0 Putative prokaryotic signal transducing protein Ribosomal_L22e PF01776.17 KXS16536.1 - 1.8e-41 140.9 0.3 3.5e-41 140.0 0.3 1.4 1 0 0 1 1 1 1 Ribosomal L22e protein family E1-E2_ATPase PF00122.20 KXS16536.1 - 6.1e-17 61.7 0.0 1.1e-16 60.9 0.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 KXS16536.1 - 4e-08 33.8 0.0 2e-07 31.5 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.21 KXS16536.1 - 1.6e-05 24.7 1.6 3e-05 23.8 1.6 1.3 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase_3 PF08282.12 KXS16536.1 - 0.0075 16.0 0.3 0.015 15.0 0.1 1.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase UL42 PF17638.2 KXS16537.1 - 0.019 15.0 1.5 0.033 14.2 1.5 1.4 1 0 0 1 1 1 0 HCMV UL42 NIF PF03031.18 KXS16538.1 - 6.9e-29 100.6 0.0 7.8e-29 100.5 0.0 1.0 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase PCRF PF03462.18 KXS16539.1 - 5.3e-57 192.8 0.8 7.1e-57 192.4 0.1 1.5 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 KXS16539.1 - 3.2e-35 120.6 1.2 3.2e-35 120.6 1.2 1.7 2 0 0 2 2 2 1 RF-1 domain DUF16 PF01519.16 KXS16539.1 - 0.026 15.0 0.7 0.13 12.8 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function DUF16 Cnd1_N PF12922.7 KXS16539.1 - 0.53 10.1 4.1 0.96 9.3 0.0 2.7 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1, N-term Enolase_C PF00113.22 KXS16540.1 - 2.7e-140 466.8 0.0 3.6e-140 466.3 0.0 1.2 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 KXS16540.1 - 1.6e-58 196.5 0.8 2.4e-58 195.9 0.8 1.3 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 KXS16540.1 - 2e-10 40.6 0.0 3.2e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 KXS16540.1 - 0.0034 16.6 0.6 0.0074 15.5 0.1 1.7 2 0 0 2 2 2 1 Methylaspartate ammonia-lyase C-terminus FAD_binding_3 PF01494.19 KXS16541.1 - 8.3e-15 54.9 1.6 5.6e-06 25.8 0.1 3.1 2 1 1 3 3 3 3 FAD binding domain NAD_binding_8 PF13450.6 KXS16541.1 - 2.2e-05 24.6 0.1 5e-05 23.5 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXS16541.1 - 0.00011 21.5 0.1 0.00042 19.6 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXS16541.1 - 0.00076 18.3 0.3 0.0019 17.0 0.1 1.6 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.24 KXS16541.1 - 0.0019 17.8 0.1 0.22 11.1 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KXS16541.1 - 0.026 13.8 0.3 0.07 12.4 0.2 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXS16541.1 - 0.051 12.7 0.1 0.082 12.0 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain DUF5528 PF17666.1 KXS16541.1 - 0.056 13.4 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5528) SE PF08491.10 KXS16541.1 - 0.068 12.2 0.1 0.11 11.6 0.1 1.2 1 0 0 1 1 1 0 Squalene epoxidase GIDA PF01134.22 KXS16541.1 - 0.11 11.5 0.0 0.16 11.0 0.0 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A GFO_IDH_MocA PF01408.22 KXS16545.1 - 1.4e-19 71.0 0.0 2.4e-19 70.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Sacchrp_dh_NADP PF03435.18 KXS16545.1 - 0.0018 18.5 0.1 0.0032 17.7 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain DapB_N PF01113.20 KXS16545.1 - 0.1 12.7 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus GFO_IDH_MocA_C PF02894.17 KXS16545.1 - 0.17 11.9 0.6 3.5 7.7 0.6 2.8 1 1 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain RRM_1 PF00076.22 KXS16546.1 - 2.8e-16 59.1 0.1 4.5e-16 58.4 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KXS16546.1 - 0.004 17.2 0.0 0.0094 16.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif Nup35_RRM_2 PF14605.6 KXS16546.1 - 0.057 13.4 0.0 0.094 12.7 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif DUF202 PF02656.15 KXS16547.1 - 7.6e-13 48.7 6.1 1.2e-12 48.1 4.5 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF4010 PF13194.6 KXS16547.1 - 0.018 14.7 1.2 0.022 14.4 1.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4010) 7tm_3 PF00003.22 KXS16547.1 - 0.023 14.4 1.4 0.028 14.1 1.4 1.1 1 0 0 1 1 1 0 7 transmembrane sweet-taste receptor of 3 GCPR SLATT_1 PF18181.1 KXS16548.1 - 0.16 11.9 1.1 0.27 11.2 1.1 1.3 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 1 MFS_1 PF07690.16 KXS16551.1 - 3.5e-21 75.5 21.9 2.5e-20 72.7 21.9 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXS16551.1 - 0.0082 15.0 1.1 0.0082 15.0 1.1 2.6 3 0 0 3 3 3 2 Sugar (and other) transporter MFS_3 PF05977.13 KXS16551.1 - 0.04 12.3 2.3 2.8 6.2 0.0 2.3 2 0 0 2 2 2 0 Transmembrane secretion effector VIT1 PF01988.19 KXS16551.1 - 0.13 12.1 0.0 0.13 12.1 0.0 2.6 2 1 0 2 2 2 0 VIT family HKR_ArcB_TM PF18415.1 KXS16551.1 - 0.25 12.2 1.4 0.49 11.2 0.2 2.2 2 0 0 2 2 2 0 Histidine kinase receptor ArcB trans-membrane domain NDK PF00334.19 KXS16552.1 - 4.4e-38 130.3 0.0 4.9e-38 130.2 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Fasciclin PF02469.22 KXS16553.1 - 1e-33 116.3 0.6 1.8e-19 70.2 0.2 2.2 2 0 0 2 2 2 2 Fasciclin domain Fasciclin PF02469.22 KXS16554.1 - 2.3e-16 60.2 6.0 9.4e-06 25.9 0.1 3.2 2 1 0 2 2 2 2 Fasciclin domain DUF748 PF05359.11 KXS16554.1 - 0.015 15.5 0.4 0.073 13.2 0.1 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF748) Fasciclin PF02469.22 KXS16555.1 - 4.4e-34 117.4 5.7 3.7e-18 66.0 2.7 2.2 2 0 0 2 2 2 2 Fasciclin domain DUF1691 PF07950.11 KXS16555.1 - 0.0044 17.7 0.5 0.076 13.7 0.1 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF1691) Methyltransf_25 PF13649.6 KXS16556.1 - 3.6e-07 30.8 0.0 7.9e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXS16556.1 - 8.3e-05 23.3 0.0 0.00018 22.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXS16556.1 - 0.003 17.4 0.0 0.0047 16.8 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXS16556.1 - 0.032 14.9 0.0 0.099 13.3 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain UPF0146 PF03686.13 KXS16556.1 - 0.19 11.6 0.0 0.36 10.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) PhoLip_ATPase_C PF16212.5 KXS16560.1 - 4.1e-67 226.5 18.1 4.1e-67 226.5 18.1 2.7 4 0 0 4 4 4 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KXS16560.1 - 5.3e-23 80.5 0.8 1.7e-22 78.8 0.8 1.9 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 KXS16560.1 - 3.3e-12 46.3 0.0 2.3e-11 43.6 0.0 2.2 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KXS16560.1 - 5.1e-12 46.5 1.7 1.8e-05 25.2 0.0 3.9 4 0 0 4 4 4 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KXS16560.1 - 0.00037 20.3 0.3 0.0048 16.7 0.1 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KXS16560.1 - 0.0086 15.6 0.0 0.05 13.1 0.0 2.3 1 1 0 1 1 1 1 E1-E2 ATPase polyprenyl_synt PF00348.17 KXS16561.1 - 5.2e-91 304.2 0.0 6.4e-91 303.9 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Usp PF00582.26 KXS16562.1 - 1.6e-30 106.4 1.5 2.4e-30 105.9 1.5 1.2 1 0 0 1 1 1 1 Universal stress protein family SPRY PF00622.28 KXS16563.1 - 9.6e-11 41.9 0.1 9.1e-10 38.7 0.1 2.6 3 0 0 3 3 3 1 SPRY domain PHD PF00628.29 KXS16563.1 - 1.3e-07 31.4 6.5 2.2e-07 30.6 6.5 1.4 1 0 0 1 1 1 1 PHD-finger TMEM51 PF15345.6 KXS16563.1 - 0.22 11.3 2.2 1.1 9.0 0.5 2.3 2 0 0 2 2 2 0 Transmembrane protein 51 C1_1 PF00130.22 KXS16563.1 - 2.8 7.9 6.1 5.5 7.0 6.1 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Peptidase_M10 PF00413.24 KXS16564.1 - 0.046 13.6 0.0 0.094 12.6 0.0 1.4 1 0 0 1 1 1 0 Matrixin CBM_21 PF03370.13 KXS16566.1 - 7.6e-20 71.2 0.0 1e-19 70.7 0.0 1.2 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 KXS16566.1 - 3.6e-07 30.7 1.7 1.6e-05 25.4 1.7 2.2 1 1 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) ECH_1 PF00378.20 KXS16570.1 - 1.9e-24 86.3 0.0 5.5e-20 71.7 0.0 2.0 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXS16570.1 - 1.3e-07 31.4 0.0 2e-05 24.3 0.0 2.1 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 KXS16570.1 - 0.1 12.6 0.0 0.74 9.8 0.0 1.9 2 0 0 2 2 2 0 Peptidase family S49 MFS_MOT1 PF16983.5 KXS16571.1 - 7.5e-55 184.1 33.1 2.4e-30 105.2 9.6 3.1 4 0 0 4 4 4 2 Molybdate transporter of MFS superfamily Sulfate_transp PF00916.20 KXS16571.1 - 2.8e-10 39.5 18.5 6.1e-08 31.8 18.5 2.4 1 1 0 1 1 1 1 Sulfate permease family PEP-CTERM PF07589.11 KXS16571.1 - 0.15 12.2 1.7 2 8.6 1.7 3.1 1 0 0 1 1 1 0 PEP-CTERM motif Hs1pro-1_C PF07014.12 KXS16572.1 - 0.2 11.1 0.0 0.27 10.7 0.0 1.1 1 0 0 1 1 1 0 Hs1pro-1 protein C-terminus Zn_clus PF00172.18 KXS16573.1 - 3.4e-07 30.3 9.5 5.9e-07 29.5 9.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS_4 PF08448.10 KXS16573.1 - 0.0067 16.7 0.0 0.019 15.2 0.0 1.8 1 0 0 1 1 1 1 PAS fold DUF3606 PF12244.8 KXS16573.1 - 0.14 12.1 0.1 0.29 11.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) Pil1 PF13805.6 KXS16574.1 - 9.4e-24 84.3 0.5 1.2e-23 83.9 0.5 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 DUF241 PF03087.14 KXS16574.1 - 0.018 14.9 4.6 0.11 12.3 4.6 1.9 1 1 0 1 1 1 0 Arabidopsis protein of unknown function Spo12 PF05032.12 KXS16574.1 - 0.02 14.8 0.3 0.056 13.3 0.3 1.8 1 0 0 1 1 1 0 Spo12 family Seryl_tRNA_N PF02403.22 KXS16574.1 - 0.034 14.4 2.6 0.034 14.4 2.6 2.3 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF812 PF05667.11 KXS16574.1 - 0.042 12.7 3.4 0.064 12.1 3.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) APG17 PF04108.12 KXS16574.1 - 0.055 12.6 3.0 0.076 12.1 3.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg17 AATF-Che1 PF13339.6 KXS16574.1 - 0.12 13.1 3.7 0.22 12.2 3.7 1.5 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor Tropomyosin_1 PF12718.7 KXS16574.1 - 0.15 12.2 7.9 0.23 11.6 6.7 1.8 1 1 0 1 1 1 0 Tropomyosin like ABC_tran_CTD PF16326.5 KXS16574.1 - 0.15 12.3 5.6 2.1 8.7 0.1 3.1 2 1 1 3 3 3 0 ABC transporter C-terminal domain DUF4407 PF14362.6 KXS16574.1 - 0.18 11.1 2.6 0.25 10.6 2.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) BRE1 PF08647.11 KXS16574.1 - 0.29 11.2 8.3 0.53 10.4 2.2 2.6 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase T3SSipB PF16535.5 KXS16574.1 - 0.3 11.5 4.4 0.47 10.9 0.2 2.4 2 1 1 3 3 2 0 Type III cell invasion protein SipB Sec8_exocyst PF04048.14 KXS16574.1 - 0.4 10.6 2.8 0.48 10.3 0.5 2.2 2 1 1 3 3 3 0 Sec8 exocyst complex component specific domain DUF3552 PF12072.8 KXS16574.1 - 0.41 10.0 9.0 0.59 9.5 9.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Phage_GP20 PF06810.11 KXS16574.1 - 0.56 10.0 9.7 3.8 7.3 2.7 2.5 1 1 1 2 2 2 0 Phage minor structural protein GP20 APG6_N PF17675.1 KXS16574.1 - 1.2 9.6 11.6 2.1 8.8 4.4 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region TMPIT PF07851.13 KXS16574.1 - 1.6 7.9 5.4 0.8 8.9 2.9 1.6 1 1 1 2 2 2 0 TMPIT-like protein MIF4G_like_2 PF09090.11 KXS16574.1 - 1.8 7.9 6.0 3 7.2 1.1 2.1 1 1 1 2 2 2 0 MIF4G like BLOC1_2 PF10046.9 KXS16574.1 - 1.9 8.9 7.6 12 6.3 0.7 2.6 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CCDC-167 PF15188.6 KXS16574.1 - 2.9 8.3 5.0 1.2 9.5 2.2 1.7 2 0 0 2 2 1 0 Coiled-coil domain-containing protein 167 CC2-LZ PF16516.5 KXS16574.1 - 6.2 7.2 8.8 4.8 7.6 0.9 2.9 2 1 1 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator CENP-H PF05837.12 KXS16574.1 - 6.5 7.2 6.9 1.5 9.2 2.4 1.9 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Sel1 PF08238.12 KXS16575.1 - 4.5e-86 281.3 64.2 1.4e-10 41.4 1.0 11.8 12 0 0 12 12 12 11 Sel1 repeat Pkinase_Tyr PF07714.17 KXS16575.1 - 1.7e-34 119.3 0.0 2.7e-34 118.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXS16575.1 - 3.5e-33 115.1 0.0 5.1e-33 114.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain TPR_16 PF13432.6 KXS16575.1 - 1.3e-06 28.9 41.6 0.0013 19.3 0.8 8.1 5 1 4 9 9 9 4 Tetratricopeptide repeat Kinase-like PF14531.6 KXS16575.1 - 1.1e-05 24.9 0.0 1.7e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like TEX29 PF15839.5 KXS16575.1 - 0.0038 17.8 8.1 3.9 8.2 0.1 5.8 7 0 0 7 7 7 1 Testis-expressed sequence 29 protein APH PF01636.23 KXS16575.1 - 0.0069 16.3 0.0 0.027 14.4 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family TPR_6 PF13174.6 KXS16575.1 - 1.4 9.7 27.9 1.8 9.4 0.1 8.1 8 1 0 8 8 8 0 Tetratricopeptide repeat SPO22 PF08631.10 KXS16575.1 - 1.7 8.0 9.4 11 5.4 0.2 4.3 4 2 1 5 5 5 0 Meiosis protein SPO22/ZIP4 like TPR_5 PF12688.7 KXS16575.1 - 6.6 7.0 9.7 99 3.2 0.2 5.3 7 0 0 7 7 7 0 Tetratrico peptide repeat Thioredoxin PF00085.20 KXS16576.1 - 0.0045 16.9 0.0 0.011 15.7 0.0 1.7 2 0 0 2 2 2 1 Thioredoxin Peptidase_C5 PF00770.18 KXS16576.1 - 0.087 12.5 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Adenovirus endoprotease Retinal PF15449.6 KXS16579.1 - 2.8 5.6 11.5 2.9 5.6 11.5 1.0 1 0 0 1 1 1 0 Retinal protein SAWADEE PF16719.5 KXS16580.1 - 0.087 12.8 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 SAWADEE domain Tudor-knot PF11717.8 KXS16580.1 - 0.15 11.9 0.1 0.32 10.9 0.1 1.4 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain AMP-binding PF00501.28 KXS16581.1 - 2.6e-27 95.5 0.2 5.7e-16 58.1 0.0 2.5 3 0 0 3 3 3 2 AMP-binding enzyme Pkinase PF00069.25 KXS16582.1 - 9.6e-45 153.0 0.0 1.9e-33 116.0 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXS16582.1 - 1.7e-11 43.9 0.0 7.9e-11 41.7 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXS16582.1 - 0.0018 17.1 0.0 0.0029 16.4 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase p450 PF00067.22 KXS16583.1 - 2e-14 53.2 0.0 1e-11 44.3 0.0 2.9 3 0 0 3 3 3 2 Cytochrome P450 p450 PF00067.22 KXS16584.1 - 6.8e-56 189.9 0.0 1.5e-55 188.8 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Ank_2 PF12796.7 KXS16585.1 - 9.1e-16 58.2 0.7 1.8e-06 28.4 0.0 4.2 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXS16585.1 - 2.4e-15 55.1 0.2 0.031 14.8 0.0 5.9 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 KXS16585.1 - 1.2e-13 51.3 0.5 0.00015 22.3 0.0 5.1 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 KXS16585.1 - 2.2e-07 31.0 4.2 0.065 13.7 0.0 5.9 7 0 0 7 7 7 1 Ankyrin repeat Ank_5 PF13857.6 KXS16585.1 - 6.5e-05 23.1 0.9 1.3 9.5 0.1 3.9 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ion_trans PF00520.31 KXS16585.1 - 0.055 12.7 5.8 0.1 11.8 5.8 1.4 1 0 0 1 1 1 0 Ion transport protein Mito_carr PF00153.27 KXS16586.1 - 2e-70 232.8 1.0 1.2e-22 79.6 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein 2OG-FeII_Oxy_2 PF13532.6 KXS16587.1 - 6.3e-26 91.8 0.0 1.4e-25 90.7 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.16 KXS16588.1 - 5.5e-40 137.4 30.4 6.8e-40 137.1 30.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 KXS16588.1 - 2.7e-08 32.8 5.3 2.7e-08 32.8 5.3 2.8 2 1 1 3 3 3 1 MFS/sugar transport protein MFS_1_like PF12832.7 KXS16588.1 - 1.8e-05 23.8 3.1 0.00021 20.3 0.5 2.6 1 1 1 2 2 2 2 MFS_1 like family MFS_1 PF07690.16 KXS16589.1 - 0.0034 16.3 1.2 0.004 16.1 1.2 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.16 KXS16590.1 - 8.1e-10 38.1 2.0 9.1e-10 38.0 2.0 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXS16590.1 - 0.056 12.3 1.1 0.13 11.1 1.1 1.6 1 1 0 1 1 1 0 Sugar (and other) transporter Methyltransf_25 PF13649.6 KXS16591.1 - 1.1e-16 61.2 0.0 3.1e-16 59.9 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXS16591.1 - 6.8e-14 52.3 0.1 2.4e-13 50.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXS16591.1 - 4.9e-13 49.6 0.0 9.5e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXS16591.1 - 7.7e-10 38.8 0.0 1.1e-09 38.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXS16591.1 - 9.3e-10 38.6 0.0 1.2e-09 38.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXS16591.1 - 2.1e-06 27.4 0.0 4.3e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 KXS16591.1 - 0.0018 17.6 0.0 0.0025 17.1 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.13 KXS16591.1 - 0.0048 16.3 0.1 0.0067 15.9 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.17 KXS16591.1 - 0.007 15.9 0.0 0.01 15.3 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase DUF3663 PF12404.8 KXS16591.1 - 0.011 15.8 2.2 0.042 13.9 2.2 1.9 1 1 0 1 1 1 0 Peptidase Methyltransf_PK PF05891.12 KXS16591.1 - 0.012 15.2 0.0 0.019 14.5 0.0 1.2 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Methyltransf_33 PF10017.9 KXS16591.1 - 0.035 13.3 0.0 0.054 12.7 0.0 1.2 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent Methyltransf_15 PF09445.10 KXS16591.1 - 0.11 12.1 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase MetW PF07021.12 KXS16591.1 - 0.17 11.5 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW adh_short PF00106.25 KXS16592.1 - 4.6e-05 23.0 0.7 0.016 14.7 0.0 2.0 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXS16592.1 - 0.0009 18.9 0.0 0.0016 18.1 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1206 PF06724.11 KXS16592.1 - 0.23 11.6 2.9 6.2 7.0 0.6 2.3 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1206) UCH PF00443.29 KXS16593.1 - 9.8e-30 103.9 0.0 1.4e-29 103.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KXS16593.1 - 2.2e-06 27.5 0.0 2.1e-05 24.3 0.0 2.4 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KXS16593.1 - 0.027 14.8 5.7 0.4 11.1 4.0 2.9 2 1 0 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein zinc_ribbon_9 PF14369.6 KXS16593.1 - 0.11 12.8 4.7 0.067 13.5 1.3 2.5 2 0 0 2 2 2 0 zinc-ribbon C1_2 PF03107.16 KXS16593.1 - 5.1 7.5 6.1 1.4 9.3 0.6 2.7 3 0 0 3 3 3 0 C1 domain Vps16_C PF04840.12 KXS16595.1 - 5.9e-77 258.8 0.0 8e-77 258.4 0.0 1.1 1 0 0 1 1 1 1 Vps16, C-terminal region Vps16_N PF04841.13 KXS16595.1 - 5.3e-72 242.8 0.0 4.2e-49 167.4 0.0 3.3 2 1 0 2 2 2 2 Vps16, N-terminal region ANAPC4_WD40 PF12894.7 KXS16595.1 - 0.012 15.9 0.0 5.8 7.3 0.0 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain ENTH PF01417.20 KXS16595.1 - 0.2 11.7 0.0 0.37 10.8 0.0 1.3 1 0 0 1 1 1 0 ENTH domain PEX11 PF05648.14 KXS16599.1 - 2.6e-16 59.8 0.0 2.8e-15 56.4 0.0 2.2 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) MMR_HSR1_C PF08438.10 KXS16600.1 - 5.4e-36 123.6 0.0 9e-36 122.9 0.0 1.4 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.23 KXS16600.1 - 1.3e-20 73.5 0.0 3.1e-20 72.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KXS16600.1 - 9.3e-09 35.0 0.1 3.2e-07 30.0 0.0 2.7 3 0 0 3 3 3 1 Ferrous iron transport protein B TAF6_C PF07571.13 KXS16600.1 - 0.0002 21.6 0.0 0.025 14.9 0.0 2.5 2 0 0 2 2 2 1 TAF6 C-terminal HEAT repeat domain RsgA_GTPase PF03193.16 KXS16600.1 - 0.0019 18.1 0.2 0.21 11.5 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 KXS16600.1 - 0.0036 17.4 0.8 0.0085 16.2 0.0 2.0 3 0 0 3 3 3 1 Dynamin family zf-H2C2_5 PF13909.6 KXS16600.1 - 0.012 15.4 1.7 0.025 14.4 1.7 1.5 1 0 0 1 1 1 0 C2H2-type zinc-finger domain TGS PF02824.21 KXS16600.1 - 0.098 12.7 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 TGS domain ATP_bind_1 PF03029.17 KXS16600.1 - 0.1 12.4 0.1 9.2 6.0 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Aldo_ket_red PF00248.21 KXS16601.1 - 3e-37 128.4 0.0 3.7e-37 128.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family FoP_duplication PF13865.6 KXS16603.1 - 3.4e-09 37.1 10.2 3.4e-09 37.1 10.2 3.4 3 1 0 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 FAD_binding_3 PF01494.19 KXS16604.1 - 2.5e-31 109.2 0.0 3.3e-16 59.5 0.0 2.4 2 0 0 2 2 2 2 FAD binding domain ApbA PF02558.16 KXS16604.1 - 0.0048 16.6 0.0 0.0084 15.8 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 KXS16604.1 - 0.0095 15.8 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 KXS16604.1 - 0.038 14.3 0.0 0.09 13.0 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox PF00070.27 KXS16604.1 - 0.077 13.6 0.2 3.7 8.2 0.0 2.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 KXS16604.1 - 0.092 12.3 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Dabb PF07876.12 KXS16605.1 - 4.7e-18 65.6 0.0 1.6e-10 41.5 0.0 2.3 2 0 0 2 2 2 2 Stress responsive A/B Barrel Domain ABM PF03992.16 KXS16605.1 - 0.0017 18.4 0.1 0.035 14.2 0.0 2.3 2 1 0 2 2 2 1 Antibiotic biosynthesis monooxygenase Ras PF00071.22 KXS16606.1 - 6.2e-25 87.7 0.0 1.5e-24 86.5 0.0 1.5 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KXS16606.1 - 8.3e-05 22.8 0.0 0.0068 16.6 0.0 2.1 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 KXS16606.1 - 0.0036 17.2 0.0 0.3 11.0 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase PduV-EutP PF10662.9 KXS16606.1 - 0.0037 17.0 0.3 2.6 7.8 0.0 2.2 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.6 KXS16606.1 - 0.022 14.5 0.2 0.029 14.1 0.2 1.4 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KXS16606.1 - 0.028 14.8 0.5 0.038 14.4 0.5 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 KXS16606.1 - 0.21 11.1 0.0 0.35 10.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region FeoB_N PF02421.18 KXS16606.1 - 0.21 11.1 0.2 2.1 7.9 0.1 2.0 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_19 PF13245.6 KXS16606.1 - 0.23 11.8 0.6 6.7 7.0 0.3 2.5 3 0 0 3 3 3 0 AAA domain RRM_1 PF00076.22 KXS16607.1 - 0.011 15.5 0.0 0.68 9.8 0.0 2.7 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) F-box-like PF12937.7 KXS16608.1 - 0.1 12.5 0.7 0.24 11.3 0.7 1.6 1 0 0 1 1 1 0 F-box-like Keratin_2_head PF16208.5 KXS16610.1 - 0.091 12.9 9.3 0.12 12.6 9.3 1.1 1 0 0 1 1 1 0 Keratin type II head Late_protein_L2 PF00513.18 KXS16610.1 - 0.095 11.7 5.9 0.12 11.4 5.9 1.1 1 0 0 1 1 1 0 Late Protein L2 Amino_oxidase PF01593.24 KXS16613.1 - 1e-39 137.1 0.0 6.2e-38 131.2 0.0 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KXS16613.1 - 7e-12 45.4 0.0 2.4e-11 43.7 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXS16613.1 - 4.5e-10 39.6 0.4 1e-09 38.5 0.4 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KXS16613.1 - 2.8e-08 33.3 1.1 3.9e-08 32.8 0.1 1.6 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 KXS16613.1 - 3.6e-05 23.0 0.0 6.5e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 KXS16613.1 - 8.8e-05 21.7 0.4 0.00013 21.2 0.4 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KXS16613.1 - 0.00011 21.6 0.1 0.00044 19.6 0.1 1.9 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXS16613.1 - 0.00099 19.1 0.0 0.0017 18.3 0.0 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding HI0933_like PF03486.14 KXS16613.1 - 0.0014 17.4 0.0 0.0023 16.7 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.7 KXS16613.1 - 0.0031 16.9 0.0 0.0041 16.5 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KXS16613.1 - 0.11 13.1 0.3 0.7 10.5 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXS16613.1 - 0.11 11.8 1.0 0.14 11.4 0.2 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KXS16613.1 - 0.26 10.3 0.1 0.35 9.9 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Mqo PF06039.15 KXS16613.1 - 0.26 9.8 0.0 0.37 9.3 0.0 1.1 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) ECH_1 PF00378.20 KXS16614.1 - 2.2e-35 122.2 0.1 7e-30 104.2 0.0 2.1 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXS16614.1 - 3.3e-18 66.3 0.1 1.9e-15 57.2 0.0 2.1 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase B12D PF06522.11 KXS16615.1 - 4.9e-13 48.7 0.2 5.9e-13 48.4 0.2 1.1 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit MaoC_dehydratas PF01575.19 KXS16616.1 - 6.8e-23 80.6 0.0 1.2e-22 79.8 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 KXS16616.1 - 5.7e-05 23.3 0.0 0.12 12.5 0.0 2.3 2 0 0 2 2 2 2 N-terminal half of MaoC dehydratase CRAL_TRIO PF00650.20 KXS16617.1 - 2.7e-10 40.2 0.4 2.8e-05 23.9 0.0 2.2 2 0 0 2 2 2 2 CRAL/TRIO domain Methyltransf_23 PF13489.6 KXS16618.1 - 1.8e-18 66.9 0.0 2.8e-18 66.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXS16618.1 - 1.2e-17 64.2 0.0 1.5e-17 63.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXS16618.1 - 7.6e-17 61.7 0.0 1.3e-16 61.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXS16618.1 - 3.2e-16 59.8 0.0 5.9e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXS16618.1 - 3.9e-10 40.4 0.0 6.1e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXS16618.1 - 1.7e-08 34.1 0.0 2.5e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family RrnaAD PF00398.20 KXS16618.1 - 0.00095 18.3 0.0 0.0018 17.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase MetW PF07021.12 KXS16618.1 - 0.018 14.6 0.0 0.027 14.0 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW RTTN_N PF14726.6 KXS16618.1 - 0.062 14.1 0.0 0.19 12.5 0.0 1.7 2 0 0 2 2 2 0 Rotatin, an armadillo repeat protein, centriole functioning His_biosynth PF00977.21 KXS16619.1 - 2.8e-07 30.3 0.0 3.6e-07 29.9 0.0 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein BtpA PF03437.15 KXS16619.1 - 0.011 15.2 0.0 0.014 14.9 0.0 1.1 1 0 0 1 1 1 0 BtpA family DRMBL PF07522.14 KXS16620.1 - 1.4e-19 70.3 0.1 9.8e-18 64.4 0.1 3.1 2 1 1 3 3 3 1 DNA repair metallo-beta-lactamase RMMBL PF07521.12 KXS16620.1 - 0.071 13.0 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Zn-dependent metallo-hydrolase RNA specificity domain Mito_carr PF00153.27 KXS16621.1 - 6.8e-10 38.7 0.0 0.0036 17.2 0.0 4.8 4 1 0 4 4 4 4 Mitochondrial carrier protein IMPDH PF00478.25 KXS16622.1 - 4.9e-134 446.7 6.9 6.2e-134 446.4 6.9 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 KXS16622.1 - 2.3e-15 56.8 0.5 2.1e-08 34.5 0.1 2.7 2 0 0 2 2 2 2 CBS domain NMO PF03060.15 KXS16622.1 - 2.1e-13 50.4 2.2 9.4e-10 38.4 2.2 2.3 2 0 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.18 KXS16622.1 - 9.5e-09 34.7 9.4 1.7e-07 30.6 6.3 2.6 2 1 0 2 2 2 2 FMN-dependent dehydrogenase His_biosynth PF00977.21 KXS16622.1 - 0.00021 20.8 2.8 0.0011 18.5 0.6 2.3 1 1 1 2 2 2 1 Histidine biosynthesis protein DUF561 PF04481.12 KXS16622.1 - 0.021 14.0 0.6 0.31 10.2 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF561) Aldolase PF01081.19 KXS16622.1 - 0.026 14.0 0.5 0.026 14.0 0.5 2.0 2 0 0 2 2 2 0 KDPG and KHG aldolase B12-binding PF02310.19 KXS16622.1 - 0.028 14.4 0.3 0.1 12.6 0.2 2.0 2 0 0 2 2 2 0 B12 binding domain ThiG PF05690.14 KXS16622.1 - 0.036 13.4 3.5 0.072 12.4 3.5 1.6 1 1 0 1 1 1 0 Thiazole biosynthesis protein ThiG NanE PF04131.14 KXS16622.1 - 0.037 13.2 1.4 0.11 11.6 1.4 2.0 1 1 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase DHO_dh PF01180.21 KXS16622.1 - 0.053 12.7 0.3 0.053 12.7 0.3 2.4 3 0 0 3 3 3 0 Dihydroorotate dehydrogenase TMEM223 PF14640.6 KXS16623.1 - 0.13 12.4 0.3 0.51 10.5 0.1 1.9 2 0 0 2 2 2 0 Transmembrane protein 223 Saf_2TM PF18303.1 KXS16624.1 - 5.4 6.6 10.3 0.4 10.3 0.6 2.9 2 1 1 3 3 3 0 SAVED-fused 2TM effector domain Syndecan PF01034.20 KXS16625.1 - 0.17 11.8 0.2 0.76 9.7 0.0 2.2 1 1 0 1 1 1 0 Syndecan domain Abhydrolase_1 PF00561.20 KXS16626.1 - 2.2e-24 86.5 0.2 6.5e-24 85.0 0.2 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXS16626.1 - 6.7e-14 53.0 8.7 6.7e-14 53.0 8.7 2.4 2 1 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXS16626.1 - 1.3e-10 41.0 0.0 3.1e-10 39.7 0.0 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 KXS16626.1 - 0.024 14.4 0.0 0.054 13.3 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Lipase_3 PF01764.25 KXS16626.1 - 0.037 13.9 0.0 0.063 13.1 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF1057 PF06342.12 KXS16626.1 - 0.051 12.6 0.0 0.079 12.0 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) DUF915 PF06028.11 KXS16626.1 - 0.099 12.0 0.0 0.24 10.7 0.0 1.5 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Ndr PF03096.14 KXS16626.1 - 0.14 10.8 0.0 0.2 10.3 0.0 1.2 1 0 0 1 1 1 0 Ndr family zf-CHCC PF10276.9 KXS16627.1 - 2.2e-16 59.6 3.5 3.2e-16 59.1 3.5 1.3 1 0 0 1 1 1 1 Zinc-finger domain zf_C2H2_6 PF18450.1 KXS16627.1 - 0.21 11.3 0.1 0.44 10.3 0.1 1.5 1 0 0 1 1 1 0 Zinc Finger domain Abhydrolase_1 PF00561.20 KXS16628.1 - 5.7e-20 72.0 0.0 2.4e-19 70.0 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXS16628.1 - 1.4e-12 48.7 2.0 3.3e-11 44.2 2.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXS16628.1 - 0.00064 19.1 0.3 0.0023 17.2 0.2 1.7 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Ndr PF03096.14 KXS16628.1 - 0.017 13.9 0.0 0.025 13.3 0.0 1.2 1 0 0 1 1 1 0 Ndr family DOPA_dioxygen PF08883.11 KXS16629.1 - 9.1e-27 93.4 0.4 1.3e-26 92.9 0.4 1.2 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family Epimerase PF01370.21 KXS16630.1 - 8e-24 84.4 0.0 1.1e-23 84.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXS16630.1 - 2.6e-14 53.4 0.0 3.8e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KXS16630.1 - 5.2e-10 38.8 0.0 3.9e-09 35.9 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KXS16630.1 - 2.7e-09 36.6 0.0 4.1e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 KXS16630.1 - 3.3e-07 30.4 0.0 7.1e-07 29.3 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KXS16630.1 - 8.7e-06 25.1 0.0 1.3e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 KXS16630.1 - 0.0011 18.2 0.3 0.017 14.3 0.3 2.5 1 1 0 1 1 1 1 Male sterility protein DUF1731 PF08338.11 KXS16630.1 - 0.12 12.2 0.0 0.33 10.8 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1731) MFS_1 PF07690.16 KXS16631.1 - 2.7e-38 131.8 31.1 3.5e-38 131.4 31.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 KXS16631.1 - 0.0075 15.6 7.5 0.0075 15.6 7.5 2.3 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB DSRB PF10781.9 KXS16631.1 - 0.01 15.5 0.0 0.024 14.3 0.0 1.6 1 0 0 1 1 1 0 Dextransucrase DSRB BRAP2 PF07576.12 KXS16632.1 - 7.2e-27 93.5 0.0 1.2e-26 92.8 0.0 1.3 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.19 KXS16632.1 - 4.3e-19 68.6 2.8 4.3e-19 68.6 2.8 1.9 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.6 KXS16632.1 - 6.1e-07 29.7 6.9 6.1e-07 29.7 6.9 2.1 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 KXS16632.1 - 6.7e-07 29.1 7.5 1.6e-06 27.9 7.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXS16632.1 - 3.2e-06 27.0 3.0 3.2e-06 27.0 3.0 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 KXS16632.1 - 1.2e-05 25.2 3.2 1.2e-05 25.2 3.2 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KXS16632.1 - 4.7e-05 23.2 5.6 0.00012 21.9 5.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KXS16632.1 - 0.00022 20.9 0.7 0.00022 20.9 0.7 2.0 2 0 0 2 2 1 1 RING-like zinc finger UPF0242 PF06785.11 KXS16632.1 - 0.00082 19.5 9.2 0.0013 18.9 9.2 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus DUF812 PF05667.11 KXS16632.1 - 0.00094 18.2 2.1 0.0013 17.7 2.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) zf-rbx1 PF12678.7 KXS16632.1 - 0.0019 18.4 3.9 0.0056 16.9 3.9 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 KXS16632.1 - 0.0063 16.4 2.6 0.0063 16.4 2.6 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DUF4407 PF14362.6 KXS16632.1 - 0.019 14.4 6.1 0.029 13.7 6.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Prok-RING_4 PF14447.6 KXS16632.1 - 0.023 14.5 1.5 0.023 14.5 1.5 2.7 3 0 0 3 3 2 0 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KXS16632.1 - 0.029 14.4 2.6 0.062 13.3 2.6 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger FapA PF03961.13 KXS16632.1 - 0.061 11.9 3.3 0.083 11.5 3.3 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A PKcGMP_CC PF16808.5 KXS16632.1 - 0.062 13.2 2.4 0.56 10.1 0.2 3.0 3 0 0 3 3 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase AIP3 PF03915.13 KXS16632.1 - 0.067 12.3 5.1 0.096 11.8 5.1 1.1 1 0 0 1 1 1 0 Actin interacting protein 3 DUF4618 PF15397.6 KXS16632.1 - 0.1 12.0 9.8 0.14 11.6 9.4 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) Spc7 PF08317.11 KXS16632.1 - 0.11 11.4 11.8 0.16 10.8 11.8 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein TMF_TATA_bd PF12325.8 KXS16632.1 - 0.14 12.3 15.2 0.1 12.8 12.3 1.8 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding zf-UBP_var PF17807.1 KXS16632.1 - 0.26 11.1 2.1 5.2 6.9 0.3 2.3 2 0 0 2 2 2 0 Variant UBP zinc finger Seryl_tRNA_N PF02403.22 KXS16632.1 - 0.37 11.0 10.0 0.71 10.1 3.8 2.3 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Zn_ribbon_17 PF17120.5 KXS16632.1 - 0.6 9.8 7.8 0.69 9.6 1.4 2.4 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type FlxA PF14282.6 KXS16632.1 - 0.67 10.0 5.4 1.2 9.2 5.0 1.6 1 1 0 1 1 1 0 FlxA-like protein Phage_GP20 PF06810.11 KXS16632.1 - 0.72 9.6 7.4 2.4 7.9 7.4 1.7 1 1 0 1 1 1 0 Phage minor structural protein GP20 FlaC_arch PF05377.11 KXS16632.1 - 1.2 9.6 8.1 0.96 9.9 0.9 2.7 1 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Fib_alpha PF08702.10 KXS16632.1 - 1.4 9.1 5.1 2.3 8.4 5.1 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF3584 PF12128.8 KXS16632.1 - 1.8 6.0 12.3 3.1 5.2 11.3 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Rubredoxin_2 PF18073.1 KXS16632.1 - 2.1 8.2 8.0 0.059 13.1 1.5 1.8 2 0 0 2 2 1 0 Rubredoxin metal binding domain FUSC PF04632.12 KXS16632.1 - 2.1 6.8 4.4 3.2 6.2 4.4 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Exonuc_VII_L PF02601.15 KXS16632.1 - 2.4 7.7 5.8 3.7 7.0 5.8 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Prefoldin_2 PF01920.20 KXS16632.1 - 2.6 8.1 13.3 0.12 12.3 1.0 3.0 1 1 2 3 3 3 0 Prefoldin subunit Baculo_PEP_C PF04513.12 KXS16632.1 - 3.2 7.8 7.2 14 5.7 7.2 1.9 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Syntaxin-6_N PF09177.11 KXS16632.1 - 3.9 8.1 10.2 12 6.5 10.2 1.8 1 1 0 1 1 1 0 Syntaxin 6, N-terminal CENP-F_leu_zip PF10473.9 KXS16632.1 - 6 6.9 19.6 9.6 6.2 18.8 1.7 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DZR PF12773.7 KXS16632.1 - 7.3 6.7 7.6 46 4.1 7.6 2.1 1 1 0 1 1 1 0 Double zinc ribbon SHE3 PF17078.5 KXS16632.1 - 7.6 6.2 11.7 19 4.9 6.6 2.1 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 DUF2968 PF11180.8 KXS16632.1 - 7.7 6.1 12.1 0.92 9.1 6.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) UCH PF00443.29 KXS16633.1 - 7.5e-62 209.1 0.0 9.7e-62 208.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KXS16633.1 - 9.9e-13 48.4 0.0 3.5e-10 40.0 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.20 KXS16633.1 - 0.072 13.6 0.0 0.73 10.4 0.0 2.3 2 0 0 2 2 2 0 Rhodanese-like domain SIS PF01380.22 KXS16634.1 - 2e-61 205.6 0.1 8.8e-34 116.2 0.0 2.5 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 KXS16634.1 - 2.2e-17 63.5 0.0 5.6e-17 62.2 0.0 1.6 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_7 PF13537.6 KXS16634.1 - 3.7e-12 46.2 0.0 9.5e-12 44.9 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 KXS16634.1 - 0.0029 16.5 0.0 0.005 15.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferases class-II DUF992 PF06186.11 KXS16636.1 - 0.22 11.4 0.3 12 5.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF992) ORC2 PF04084.14 KXS16637.1 - 1.7e-83 280.3 0.0 2.3e-83 279.9 0.0 1.2 1 0 0 1 1 1 1 Origin recognition complex subunit 2 BUD22 PF09073.10 KXS16637.1 - 1.9 7.7 20.6 0.9 8.8 11.4 2.4 2 0 0 2 2 2 0 BUD22 CobT PF06213.12 KXS16637.1 - 3.8 6.8 19.3 3.1 7.1 0.5 2.9 3 0 0 3 3 3 0 Cobalamin biosynthesis protein CobT CDC45 PF02724.14 KXS16637.1 - 5.9 5.0 15.1 1.4 7.1 7.0 2.1 2 0 0 2 2 2 0 CDC45-like protein Nop14 PF04147.12 KXS16637.1 - 6 4.9 17.6 0.12 10.6 7.9 2.0 2 0 0 2 2 2 0 Nop14-like family DUF1908 PF08926.11 KXS16639.1 - 0.76 8.8 4.3 1.1 8.3 4.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1908) Gti1_Pac2 PF09729.9 KXS16640.1 - 1.4e-43 149.1 2.3 1.7e-38 132.5 0.2 2.8 2 1 1 3 3 3 2 Gti1/Pac2 family EAP30 PF04157.16 KXS16641.1 - 5.3e-64 215.7 0.0 6e-64 215.5 0.0 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family Phage_Mu_Gam PF07352.12 KXS16641.1 - 0.046 13.6 1.1 0.076 12.9 1.1 1.2 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein Ribosomal_L19 PF01245.20 KXS16643.1 - 1.6e-19 69.9 0.0 2.4e-19 69.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L19 Arf PF00025.21 KXS16644.1 - 1.5e-76 255.7 0.1 1.8e-76 255.5 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KXS16644.1 - 7e-15 55.3 0.1 9.3e-15 54.9 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 KXS16644.1 - 2.9e-11 43.1 0.7 8.2e-07 28.5 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 KXS16644.1 - 6.5e-11 42.0 0.0 8.1e-11 41.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 KXS16644.1 - 1.3e-10 41.1 0.0 1.6e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KXS16644.1 - 8e-09 35.2 0.0 1e-08 34.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KXS16644.1 - 1.5e-05 25.0 0.0 2.9e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase MeaB PF03308.16 KXS16644.1 - 0.0039 16.2 0.4 0.21 10.5 0.1 2.7 2 1 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB GTP_EFTU PF00009.27 KXS16644.1 - 0.0044 16.6 0.2 0.039 13.5 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_18 PF13238.6 KXS16644.1 - 0.012 16.2 0.0 0.017 15.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 KXS16644.1 - 0.08 12.5 0.4 9.1 5.8 0.1 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.27 KXS16644.1 - 0.18 12.3 0.1 0.38 11.3 0.1 1.6 2 0 0 2 2 2 0 ABC transporter NumbF PF06311.12 KXS16646.1 - 0.0049 17.4 0.6 0.0087 16.6 0.6 1.5 1 0 0 1 1 1 1 NUMB domain SOG2 PF10428.9 KXS16648.1 - 5.5 6.1 10.9 6.5 5.8 10.9 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DUF5316 PF17247.2 KXS16650.1 - 0.14 12.2 0.5 0.17 11.9 0.5 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF5316) Lactamase_B PF00753.27 KXS16651.1 - 5.2e-10 39.7 0.3 6.9e-10 39.3 0.3 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KXS16651.1 - 0.00012 21.7 0.2 0.00018 21.1 0.2 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain PDEase_II PF02112.15 KXS16651.1 - 0.15 11.2 0.1 0.19 10.8 0.1 1.2 1 0 0 1 1 1 0 cAMP phosphodiesterases class-II zf-H2C2_2 PF13465.6 KXS16654.1 - 1.7e-12 47.2 9.1 2.4e-06 27.7 0.3 3.5 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.26 KXS16654.1 - 3.1e-12 46.2 10.3 0.00015 22.0 1.0 3.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXS16654.1 - 1.3e-08 34.9 11.7 0.0029 18.3 0.8 3.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C4_ClpX PF06689.13 KXS16654.1 - 0.00059 19.7 1.0 0.87 9.5 0.3 2.7 2 1 0 2 2 2 2 ClpX C4-type zinc finger zf-C2H2_jaz PF12171.8 KXS16654.1 - 0.00066 19.9 1.2 0.64 10.4 0.1 2.8 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KXS16654.1 - 0.0012 18.8 0.3 0.0012 18.8 0.3 2.8 3 0 0 3 3 3 1 C2H2-type zinc finger zf-MYST PF17772.1 KXS16654.1 - 0.0037 16.8 2.3 0.48 10.1 0.1 2.2 1 1 1 2 2 2 2 MYST family zinc finger domain zf-C2H2_11 PF16622.5 KXS16654.1 - 0.0097 15.6 2.1 0.26 11.1 0.4 2.5 2 0 0 2 2 2 1 zinc-finger C2H2-type DUF2757 PF10955.8 KXS16654.1 - 0.011 16.0 0.7 2.2 8.6 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2757) IBR PF01485.21 KXS16654.1 - 0.041 14.1 0.7 0.041 14.1 0.7 1.9 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain C1_4 PF07975.12 KXS16654.1 - 0.045 14.0 0.4 0.045 14.0 0.4 2.0 1 1 1 2 2 2 0 TFIIH C1-like domain zinc_ribbon_15 PF17032.5 KXS16654.1 - 0.048 14.4 1.6 0.056 14.2 1.3 1.3 1 1 0 1 1 1 0 zinc-ribbon family XPA_N PF01286.18 KXS16654.1 - 0.066 13.3 1.7 4.4 7.4 0.1 2.3 2 0 0 2 2 2 0 XPA protein N-terminal zinc_ribbon_10 PF10058.9 KXS16654.1 - 0.24 11.2 2.8 4.2 7.2 0.2 2.2 1 1 1 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein zf-C2HC_2 PF13913.6 KXS16654.1 - 0.31 11.0 0.4 0.31 11.0 0.4 3.0 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf_ZIC PF18366.1 KXS16654.1 - 0.56 10.3 4.8 3.4 7.9 0.2 3.0 1 1 2 3 3 3 0 Zic proteins zinc finger domain zf-AN1 PF01428.16 KXS16654.1 - 0.65 10.2 7.8 1.1 9.5 1.8 2.9 1 1 1 2 2 2 0 AN1-like Zinc finger Methyltransf_3 PF01596.17 KXS16656.1 - 0.00085 18.6 0.0 0.0092 15.2 0.0 2.1 1 1 0 1 1 1 1 O-methyltransferase Sel1 PF08238.12 KXS16660.1 - 4.1e-21 75.0 8.3 8.2e-05 23.2 0.0 4.9 5 0 0 5 5 5 4 Sel1 repeat Pkinase_Tyr PF07714.17 KXS16661.1 - 2e-08 33.8 0.0 3.4e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXS16661.1 - 0.062 12.7 0.0 0.3 10.4 0.0 1.8 2 0 0 2 2 2 0 Protein kinase domain Aminotran_1_2 PF00155.21 KXS16662.1 - 9.2e-44 150.1 0.0 1.2e-43 149.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KXS16662.1 - 3.3e-06 26.3 0.0 5.5e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KXS16662.1 - 0.0052 16.1 0.0 0.012 14.9 0.0 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase NIR_SIR_ferr PF03460.17 KXS16662.1 - 0.043 13.7 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Nitrite/Sulfite reductase ferredoxin-like half domain VWA_CoxE PF05762.14 KXS16662.1 - 0.067 12.6 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein Cys_Met_Meta_PP PF01053.20 KXS16662.1 - 0.14 10.7 0.0 0.26 9.8 0.0 1.4 1 1 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Glyco_hydro_20 PF00728.22 KXS16664.1 - 3.8e-13 49.6 0.0 1.6e-12 47.5 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 KXS16664.1 - 0.00012 22.8 0.0 0.00022 21.9 0.0 1.4 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 KXS16664.1 - 0.088 13.6 0.0 0.31 11.8 0.0 1.9 2 0 0 2 2 2 0 Glycosyl hydrolase family 20, domain 2 Ank_2 PF12796.7 KXS16665.1 - 5.2e-18 65.4 1.2 8.5e-12 45.5 0.2 2.3 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXS16665.1 - 1.7e-08 34.6 5.7 0.0012 19.1 0.2 4.5 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXS16665.1 - 6.1e-07 29.9 0.3 0.017 15.7 0.1 3.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXS16665.1 - 8e-07 28.9 1.4 0.95 10.2 0.0 5.1 4 1 1 5 5 5 2 Ankyrin repeat Ank PF00023.30 KXS16665.1 - 3e-06 27.4 7.5 2.7 8.6 0.1 5.5 5 1 0 5 5 5 3 Ankyrin repeat PELOTA_1 PF15608.6 KXS16665.1 - 0.07 13.0 0.1 6.9 6.6 0.0 3.0 3 0 0 3 3 3 0 PELOTA RNA binding domain F-box-like_2 PF13013.6 KXS16665.1 - 0.18 11.8 0.0 0.48 10.4 0.0 1.8 1 1 0 1 1 1 0 F-box-like domain Asp PF00026.23 KXS16666.1 - 0.0013 18.2 0.0 0.0032 16.9 0.0 1.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Coprogen_oxidas PF01218.18 KXS16667.1 - 1.2e-127 424.7 0.0 1.5e-127 424.4 0.0 1.1 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase Myotub-related PF06602.14 KXS16669.1 - 2.5e-133 444.4 0.0 3e-133 444.1 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain DSPc PF00782.20 KXS16669.1 - 0.0053 16.6 0.0 0.0098 15.7 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KXS16669.1 - 0.009 15.6 0.0 0.014 14.9 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 KXS16669.1 - 0.2 11.6 0.0 0.32 10.9 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family zf-C2H2 PF00096.26 KXS16670.1 - 2.3e-11 43.5 11.8 0.00072 19.9 0.2 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXS16670.1 - 1.1e-07 32.1 13.4 0.0098 16.7 0.2 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KXS16670.1 - 0.0011 19.2 1.7 0.0011 19.2 1.7 3.4 3 0 0 3 3 3 1 Zinc-finger double domain FYDLN_acid PF09538.10 KXS16670.1 - 0.036 14.7 1.6 0.069 13.8 0.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) zf-C2H2_6 PF13912.6 KXS16670.1 - 0.073 13.1 5.5 0.21 11.7 0.7 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger Zn_ribbon_17 PF17120.5 KXS16670.1 - 0.1 12.3 1.2 13 5.5 0.0 2.4 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-TRAF PF02176.18 KXS16670.1 - 2.1 9.1 8.3 0.14 12.8 1.3 2.2 2 0 0 2 2 2 0 TRAF-type zinc finger Lipase_GDSL_2 PF13472.6 KXS16671.1 - 1.2e-22 81.2 0.0 1.4e-22 80.9 0.0 1.0 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KXS16671.1 - 1.3e-06 28.5 0.0 3e-06 27.4 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Ytp1 PF10355.9 KXS16672.1 - 5e-07 29.2 5.8 0.0004 19.7 3.6 3.7 2 1 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 KXS16672.1 - 5.5e-06 26.1 6.5 3.5e-05 23.5 0.9 2.9 3 0 0 3 3 3 2 Domain of unknown function (DUF2427) DUF4079 PF13301.6 KXS16672.1 - 0.015 15.4 6.6 0.27 11.4 6.6 2.8 1 1 0 1 1 1 0 Protein of unknown function (DUF4079) Acyl-CoA_dh_1 PF00441.24 KXS16673.1 - 6.2e-31 107.6 1.0 8.9e-31 107.1 1.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.28 KXS16673.1 - 1.2e-19 70.2 0.0 2.9e-19 69.0 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.19 KXS16673.1 - 3.4e-18 65.6 0.8 7.4e-18 64.5 0.8 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KXS16673.1 - 9.4e-16 58.5 0.4 9.3e-15 55.3 0.5 2.6 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KXS16673.1 - 9.8e-06 25.9 0.1 1.9e-05 25.0 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain RRM_1 PF00076.22 KXS16674.1 - 7e-11 41.8 0.1 1.3e-10 40.9 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CDKN3 PF05706.12 KXS16677.1 - 6.1e-06 26.0 0.1 1.2e-05 25.1 0.1 1.4 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) DSPc PF00782.20 KXS16677.1 - 4.6e-05 23.2 0.0 7.9e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 KXS16677.1 - 0.0007 19.7 0.0 0.0014 18.8 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate Chitin_synth_2 PF03142.15 KXS16678.1 - 6.7e-223 741.1 0.9 9.8e-223 740.5 0.9 1.2 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 KXS16678.1 - 1e-111 374.3 0.0 2.4e-111 373.1 0.0 1.5 1 1 0 1 1 1 1 Myosin head (motor domain) DEK_C PF08766.11 KXS16678.1 - 3.2e-14 52.6 2.1 3.9e-14 52.3 0.2 2.2 3 0 0 3 3 3 1 DEK C terminal domain Cyt-b5 PF00173.28 KXS16678.1 - 1.3e-13 50.9 0.1 5e-07 29.8 0.0 2.6 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_trans_2_3 PF13632.6 KXS16678.1 - 4.9e-12 46.2 0.4 4.9e-12 46.2 0.4 1.9 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KXS16678.1 - 3.2e-11 43.6 0.0 1.1e-10 41.8 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KXS16678.1 - 0.00026 20.8 0.0 0.056 13.2 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 AAA_22 PF13401.6 KXS16678.1 - 0.0076 16.5 0.0 0.024 14.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain F-box-like PF12937.7 KXS16679.1 - 6e-05 22.8 1.0 0.00052 19.9 1.0 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KXS16679.1 - 0.001 18.9 0.2 0.0022 17.8 0.2 1.7 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KXS16679.1 - 0.0063 16.4 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 F-box YscO-like PF16789.5 KXS16680.1 - 0.087 12.9 1.4 0.12 12.4 1.4 1.1 1 0 0 1 1 1 0 YscO-like protein BAR PF03114.18 KXS16682.1 - 0.0033 17.1 0.7 0.0042 16.8 0.7 1.2 1 0 0 1 1 1 1 BAR domain RPW8 PF05659.11 KXS16682.1 - 0.06 13.0 1.2 0.067 12.9 0.3 1.6 2 0 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 YabA PF06156.13 KXS16682.1 - 0.22 12.2 1.1 0.33 11.6 0.7 1.6 1 1 0 1 1 1 0 Initiation control protein YabA AA_permease_2 PF13520.6 KXS16683.1 - 2.8e-52 178.0 54.3 3.3e-52 177.7 54.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXS16683.1 - 8.8e-22 77.3 48.0 1.3e-21 76.8 48.0 1.1 1 0 0 1 1 1 1 Amino acid permease F5_F8_type_C PF00754.25 KXS16684.1 - 0.00069 19.7 3.9 0.0041 17.2 0.1 2.5 2 1 1 3 3 3 2 F5/8 type C domain DAP10 PF07213.11 KXS16685.1 - 0.014 15.3 0.6 0.04 13.9 0.6 1.7 1 0 0 1 1 1 0 DAP10 membrane protein Podoplanin PF05808.11 KXS16685.1 - 0.073 13.2 2.6 0.15 12.2 2.6 1.5 1 0 0 1 1 1 0 Podoplanin EphA2_TM PF14575.6 KXS16685.1 - 0.15 12.9 0.0 0.36 11.7 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain CD225 PF04505.12 KXS16685.1 - 2.6 8.2 5.8 0.41 10.8 0.4 2.5 2 0 0 2 2 2 0 Interferon-induced transmembrane protein SKG6 PF08693.10 KXS16685.1 - 5.3 6.5 12.7 16 5.0 12.7 1.9 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Podoplanin PF05808.11 KXS16686.1 - 0.014 15.5 0.8 0.033 14.3 0.8 1.6 1 0 0 1 1 1 0 Podoplanin MFS_1 PF07690.16 KXS16687.1 - 1.6e-24 86.5 56.8 7.9e-22 77.7 27.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KXS16687.1 - 0.00097 18.1 13.4 0.0047 15.8 9.8 2.2 2 0 0 2 2 2 2 MFS_1 like family MFS_1 PF07690.16 KXS16688.1 - 0.0022 17.0 5.8 0.0026 16.7 5.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 KXS16688.1 - 0.046 12.0 0.1 0.05 11.9 0.1 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Alveol-reg_P311 PF11092.8 KXS16688.1 - 0.16 12.1 0.0 0.26 11.4 0.0 1.3 1 0 0 1 1 1 0 Neuronal protein 3.1 (p311) Methyltransf_3 PF01596.17 KXS16690.1 - 6.3e-08 32.1 0.0 1.1e-07 31.3 0.0 1.4 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 KXS16690.1 - 3.2e-05 24.9 0.0 5.8e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PAN_3 PF08277.12 KXS16691.1 - 0.011 15.5 1.1 0.013 15.3 1.1 1.1 1 0 0 1 1 1 0 PAN-like domain RGM_C PF06534.13 KXS16691.1 - 0.015 14.8 0.0 0.015 14.8 0.0 1.1 1 0 0 1 1 1 0 Repulsive guidance molecule (RGM) C-terminus ATP_bind_3 PF01171.20 KXS16691.1 - 0.028 14.2 0.0 0.028 14.2 0.0 1.1 1 0 0 1 1 1 0 PP-loop family SH3_2 PF07653.17 KXS16692.1 - 0.0028 17.3 0.0 0.0043 16.7 0.0 1.5 1 1 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KXS16692.1 - 0.015 15.1 0.0 0.029 14.2 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain SH3_1 PF00018.28 KXS16692.1 - 0.032 13.8 0.0 0.063 12.9 0.0 1.5 2 0 0 2 2 2 0 SH3 domain SH3_1 PF00018.28 KXS16694.1 - 1.4e-07 31.0 0.0 2.9e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KXS16694.1 - 3.5e-05 23.6 0.0 6.5e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Amnionless PF14828.6 KXS16694.1 - 0.0026 16.7 0.1 0.0044 15.9 0.1 1.3 1 0 0 1 1 1 1 Amnionless DUF5036 PF16439.5 KXS16694.1 - 0.06 13.1 0.0 0.095 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5036) SH3_2 PF07653.17 KXS16694.1 - 0.15 11.8 0.0 0.31 10.8 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain DUF4436 PF14494.6 KXS16696.1 - 8.4e-26 90.8 1.0 1e-25 90.5 1.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4436) Trypsin PF00089.26 KXS16698.1 - 6.9e-26 91.4 0.1 9.8e-26 90.9 0.1 1.2 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 KXS16698.1 - 0.0032 18.4 0.1 0.0052 17.7 0.1 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain HNH_4 PF13395.6 KXS16699.1 - 0.052 13.5 0.9 0.52 10.3 0.9 2.3 1 1 0 1 1 1 0 HNH endonuclease Ank_2 PF12796.7 KXS16700.1 - 2.1e-11 44.3 0.1 3.7e-06 27.4 0.4 3.0 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXS16700.1 - 4.2e-08 32.8 0.8 3.6 8.4 0.0 5.6 6 0 0 6 6 6 3 Ankyrin repeat Ank_4 PF13637.6 KXS16700.1 - 4.2e-07 30.4 0.5 1 10.0 0.1 4.4 4 1 0 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXS16700.1 - 4.9e-06 26.7 1.4 1.3 9.4 0.0 4.9 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank PF00023.30 KXS16700.1 - 7.3e-06 26.2 1.7 0.79 10.3 0.1 5.4 6 0 0 6 6 6 1 Ankyrin repeat Glyoxalase_6 PF18029.1 KXS16701.1 - 5.1e-08 33.7 0.0 1.9e-05 25.4 0.0 2.6 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase PF00903.25 KXS16701.1 - 0.00017 21.8 0.1 0.025 14.8 0.0 3.2 3 1 0 3 3 3 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KXS16701.1 - 0.043 14.1 0.2 2.3 8.5 0.0 3.2 2 1 1 3 3 3 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Prok-RING_2 PF14445.6 KXS16703.1 - 0.095 12.9 0.0 0.62 10.3 0.0 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 2 Herpes_UL52 PF03121.15 KXS16704.1 - 0.0042 17.0 0.6 0.012 15.6 0.6 1.7 1 0 0 1 1 1 1 Herpesviridae UL52/UL70 DNA primase Dimer_Tnp_hAT PF05699.14 KXS16705.1 - 4e-12 45.8 0.0 6.5e-12 45.1 0.0 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region PDDEXK_1 PF12705.7 KXS16706.1 - 0.0056 16.6 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily Sel1 PF08238.12 KXS16707.1 - 1e-23 83.2 10.4 9.6e-08 32.5 0.5 3.1 3 0 0 3 3 3 3 Sel1 repeat HMG_box PF00505.19 KXS16711.1 - 8.6e-11 42.1 0.1 1.1e-10 41.7 0.1 1.1 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KXS16711.1 - 8.9e-05 23.0 0.0 0.00015 22.2 0.0 1.3 1 0 0 1 1 1 1 HMG-box domain AT_hook PF02178.19 KXS16711.1 - 0.02 14.7 3.8 0.047 13.6 3.8 1.7 1 0 0 1 1 1 0 AT hook motif KH_8 PF17903.1 KXS16713.1 - 3.1e-05 24.0 0.0 5e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 KXS16713.1 - 0.00013 21.7 0.1 0.00026 20.8 0.1 1.5 1 0 0 1 1 1 1 KH domain DLH PF01738.18 KXS16714.1 - 2e-42 145.2 0.0 2.3e-42 145.0 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family BAAT_C PF08840.11 KXS16714.1 - 0.0001 22.3 2.0 0.36 10.7 0.2 3.1 1 1 1 3 3 3 3 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_2 PF02230.16 KXS16714.1 - 0.032 14.1 0.0 0.044 13.6 0.0 1.1 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase eIF-5_eIF-2B PF01873.17 KXS16716.1 - 0.084 12.8 0.1 0.17 11.7 0.1 1.5 1 0 0 1 1 1 0 Domain found in IF2B/IF5 TetR_C_16 PF17920.1 KXS16718.1 - 0.0015 18.7 0.0 0.011 15.9 0.1 2.2 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain Cupredoxin_1 PF13473.6 KXS16720.1 - 0.023 14.8 0.0 0.037 14.2 0.0 1.4 1 0 0 1 1 1 0 Cupredoxin-like domain Pro_CA PF00484.19 KXS16721.1 - 1.1e-53 181.7 0.1 1.6e-53 181.2 0.1 1.2 1 0 0 1 1 1 1 Carbonic anhydrase SH3_9 PF14604.6 KXS16722.1 - 2.6e-06 27.2 0.0 5.9e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXS16722.1 - 9e-06 25.2 0.0 1.6e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KXS16722.1 - 4.9e-05 22.9 0.0 0.00018 21.1 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain DUF4436 PF14494.6 KXS16723.1 - 1.7e-27 96.4 1.5 1.9e-27 96.2 0.1 1.7 1 1 1 2 2 2 1 Domain of unknown function (DUF4436) SecD-TM1 PF13721.6 KXS16723.1 - 0.013 16.0 0.0 0.45 11.0 0.0 2.4 2 0 0 2 2 2 0 SecD export protein N-terminal TM region DUF4131 PF13567.6 KXS16723.1 - 0.32 10.6 1.6 1.8 8.2 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Sugar_tr PF00083.24 KXS16725.1 - 1.9e-31 109.4 25.4 4.6e-21 75.2 3.7 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KXS16725.1 - 2.1e-16 59.8 39.3 3.2e-15 55.9 16.1 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily DUF2512 PF10710.9 KXS16725.1 - 0.17 11.5 5.3 0.12 12.1 1.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2512) HMG_box PF00505.19 KXS16726.1 - 4.9e-13 49.3 38.3 6.5e-07 29.7 4.7 4.6 4 1 1 5 5 5 3 HMG (high mobility group) box HMG_box_2 PF09011.10 KXS16726.1 - 6e-08 33.2 30.7 5.8e-05 23.6 4.6 4.1 2 1 1 4 4 4 3 HMG-box domain HMG_box_5 PF14887.6 KXS16726.1 - 0.023 14.7 1.7 0.023 14.7 1.7 3.0 2 1 1 3 3 3 0 HMG (high mobility group) box 5 FAM178 PF14816.6 KXS16726.1 - 0.25 10.3 0.9 0.88 8.5 0.1 1.9 1 1 1 2 2 2 0 Family of unknown function, FAM178 DUF3106 PF11304.8 KXS16726.1 - 0.29 11.6 18.9 0.74 10.3 0.9 4.3 3 2 0 3 3 3 0 Protein of unknown function (DUF3106) Arg_decarbox_C PF17944.1 KXS16726.1 - 0.62 10.7 5.7 0.47 11.1 0.5 3.1 3 1 1 4 4 4 0 Arginine decarboxylase C-terminal helical extension tRNA-synt_1e PF01406.19 KXS16726.1 - 3.7 6.8 5.3 19 4.5 5.3 1.9 1 1 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain Sel1 PF08238.12 KXS16728.1 - 4.6e-12 46.2 12.8 0.039 14.6 0.5 5.9 6 1 0 6 6 6 4 Sel1 repeat CS PF04969.16 KXS16728.1 - 4.8e-09 37.1 0.2 7.8e-09 36.4 0.2 1.4 1 0 0 1 1 1 1 CS domain zf-RING_2 PF13639.6 KXS16730.1 - 1.7e-10 41.1 6.8 2.5e-10 40.5 6.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KXS16730.1 - 1.1e-07 31.5 3.4 1.8e-07 30.7 3.4 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 KXS16730.1 - 6.5e-06 25.9 5.0 1e-05 25.3 5.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KXS16730.1 - 8.3e-06 26.0 4.4 1.6e-05 25.0 4.4 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KXS16730.1 - 4.8e-05 23.1 5.9 7.7e-05 22.5 5.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXS16730.1 - 0.0002 21.2 4.7 0.00031 20.7 4.7 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KXS16730.1 - 0.0053 16.6 4.3 0.008 16.0 4.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KXS16730.1 - 0.013 15.3 5.7 0.023 14.5 5.7 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KXS16730.1 - 0.027 14.5 2.1 0.052 13.6 2.1 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 KXS16730.1 - 0.086 12.5 3.9 0.15 11.7 3.9 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 KXS16730.1 - 0.16 12.0 3.7 0.55 10.3 3.8 1.8 1 1 0 1 1 1 0 RING-type zinc-finger zf-RING_4 PF14570.6 KXS16730.1 - 8.1 6.3 6.1 14 5.6 6.1 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 KXS16731.1 - 1.5e-09 37.4 0.7 2.7e-09 36.6 0.7 1.3 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 KXS16731.1 - 1.1e-05 25.7 0.4 1.8e-05 24.9 0.4 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KXS16731.1 - 0.0029 17.4 0.4 0.0049 16.7 0.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXS16731.1 - 0.0059 16.5 0.8 0.01 15.7 0.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXS16731.1 - 0.068 13.2 0.7 0.13 12.3 0.7 1.5 1 0 0 1 1 1 0 RING-type zinc-finger WD40 PF00400.32 KXS16732.1 - 1.4e-08 35.3 10.7 0.013 16.3 0.7 6.0 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXS16732.1 - 8.6e-06 26.0 0.0 0.0072 16.6 0.0 3.6 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Kei1 PF08552.11 KXS16732.1 - 0.0097 15.8 5.2 0.02 14.8 5.2 1.5 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 Tetraspanin PF00335.20 KXS16732.1 - 0.026 14.2 2.2 0.045 13.4 2.2 1.4 1 0 0 1 1 1 0 Tetraspanin family SLAC1 PF03595.17 KXS16732.1 - 1.7 7.8 10.7 0.37 10.0 4.7 2.0 1 1 0 2 2 2 0 Voltage-dependent anion channel Neuroparsin PF07327.11 KXS16733.1 - 0.03 14.7 0.0 0.3 11.6 0.0 2.1 2 0 0 2 2 2 0 Neuroparsin LUD_dom PF02589.15 KXS16736.1 - 0.0019 17.9 0.1 0.0023 17.7 0.1 1.1 1 0 0 1 1 1 1 LUD domain Retrotran_gag_2 PF14223.6 KXS16737.1 - 0.028 14.1 0.4 0.037 13.7 0.4 1.2 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Dynein_C PF18199.1 KXS16738.1 - 7.1e-21 74.7 0.0 7.9e-21 74.6 0.0 1.0 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain PXA PF02194.15 KXS16740.1 - 2.4e-40 138.5 0.2 4.7e-40 137.5 0.2 1.5 1 0 0 1 1 1 1 PXA domain Nexin_C PF08628.12 KXS16740.1 - 7.2e-16 58.8 0.1 1.5e-15 57.7 0.1 1.6 1 0 0 1 1 1 1 Sorting nexin C terminal DIOX_N PF14226.6 KXS16741.1 - 8.1e-22 78.2 0.0 1.3e-21 77.5 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KXS16741.1 - 2.3e-06 28.0 0.0 4.1e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Rad52_Rad22 PF04098.15 KXS16743.1 - 3.8e-53 179.5 0.0 4.7e-53 179.2 0.0 1.0 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein ARD PF03079.14 KXS16744.1 - 2e-48 164.6 0.0 2.3e-48 164.3 0.0 1.1 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 KXS16744.1 - 1.4e-09 37.5 0.2 7e-09 35.3 0.0 2.0 2 0 0 2 2 2 1 Cupin domain AraC_binding PF02311.19 KXS16744.1 - 3.9e-06 26.8 0.0 8.4e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.22 KXS16744.1 - 0.0053 16.4 0.0 0.0092 15.6 0.0 1.3 1 0 0 1 1 1 1 Cupin zf-RanBP PF00641.18 KXS16745.1 - 6.5e-24 82.9 42.8 2.8e-09 36.1 2.0 5.4 5 1 0 6 6 6 4 Zn-finger in Ran binding protein and others DZR PF12773.7 KXS16745.1 - 2.5e-05 24.2 23.4 0.0046 17.0 1.1 4.5 4 1 0 4 4 4 4 Double zinc ribbon TackOD1 PF18551.1 KXS16745.1 - 0.013 15.2 21.9 0.047 13.3 0.5 4.8 5 0 0 5 5 5 0 Thaumarchaeal output domain 1 Prim_Zn_Ribbon PF08273.12 KXS16745.1 - 0.21 11.9 30.2 1.8 8.9 0.0 6.5 8 0 0 8 8 8 0 Zinc-binding domain of primase-helicase HypA PF01155.19 KXS16745.1 - 0.35 10.9 20.2 2 8.4 0.2 5.0 5 0 0 5 5 5 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA UCH PF00443.29 KXS16746.1 - 1.6e-33 116.3 0.0 2.5e-33 115.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KXS16746.1 - 1.3e-11 44.7 0.0 7.8e-11 42.1 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ADH_N PF08240.12 KXS16747.1 - 2.1e-16 59.7 2.3 3.3e-16 59.1 1.4 1.6 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXS16747.1 - 7e-10 39.0 0.0 1.2e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KXS16747.1 - 0.0072 15.7 0.9 0.011 15.0 0.9 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Chlorosome_CsmC PF11098.8 KXS16747.1 - 0.033 14.2 0.2 0.07 13.1 0.1 1.6 2 0 0 2 2 2 0 Chlorosome envelope protein C PSP1 PF04468.12 KXS16749.1 - 9.8e-31 105.9 1.6 1.4e-30 105.4 1.6 1.2 1 0 0 1 1 1 1 PSP1 C-terminal conserved region GCV_T PF01571.21 KXS16750.1 - 8.1e-81 271.2 0.0 9.8e-81 270.9 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 KXS16750.1 - 1e-24 86.2 0.1 2.2e-24 85.2 0.1 1.6 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain UQ_con PF00179.26 KXS16752.1 - 1.4e-42 144.6 0.0 1.6e-42 144.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UFC1 PF08694.11 KXS16752.1 - 0.003 17.2 0.0 0.0035 17.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-fold modifier-conjugating enzyme 1 CtaG_Cox11 PF04442.14 KXS16753.1 - 1.4e-58 197.2 0.1 1.9e-58 196.8 0.1 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 PRP38 PF03371.15 KXS16754.1 - 1.2e-57 194.5 0.1 1.5e-57 194.2 0.1 1.1 1 0 0 1 1 1 1 PRP38 family SART-1 PF03343.13 KXS16754.1 - 3.2e-06 26.0 0.2 3.2e-06 26.0 0.2 3.1 2 1 1 3 3 3 2 SART-1 family Retinal PF15449.6 KXS16754.1 - 0.78 7.5 18.3 0.93 7.2 18.3 1.1 1 0 0 1 1 1 0 Retinal protein Nfu_N PF08712.11 KXS16755.1 - 1.4e-27 95.6 0.0 3.6e-27 94.2 0.0 1.7 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 KXS16755.1 - 2.1e-27 95.0 0.0 3.1e-27 94.5 0.0 1.3 1 0 0 1 1 1 1 NifU-like domain Snf7 PF03357.21 KXS16755.1 - 0.06 12.9 2.3 0.12 11.9 0.0 2.0 2 0 0 2 2 2 0 Snf7 WD40 PF00400.32 KXS16756.1 - 0.53 11.3 3.0 1.9e+02 3.2 0.0 4.9 5 0 0 5 5 5 0 WD domain, G-beta repeat Spot_14 PF07084.12 KXS16756.1 - 0.74 9.9 4.5 0.91 9.6 0.1 2.7 2 0 0 2 2 2 0 Thyroid hormone-inducible hepatic protein Spot 14 DHHC PF01529.20 KXS16757.1 - 3e-36 124.5 3.9 3e-36 124.5 3.9 2.5 2 1 0 2 2 2 1 DHHC palmitoyltransferase DJ-1_PfpI PF01965.24 KXS16759.1 - 3.6e-21 75.7 0.1 5.1e-21 75.2 0.1 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 KXS16759.1 - 0.042 13.5 0.0 0.062 13.0 0.0 1.2 1 0 0 1 1 1 0 ThiJ/PfpI family-like F-box-like PF12937.7 KXS16761.1 - 2.2e-05 24.3 0.5 2.2e-05 24.3 0.5 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KXS16761.1 - 0.028 14.3 0.5 0.14 12.1 0.0 2.4 2 0 0 2 2 2 0 F-box domain PGM_PMM_I PF02878.16 KXS16763.1 - 1.6e-17 63.5 0.2 1.4e-08 34.5 0.1 3.0 3 0 0 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 KXS16763.1 - 4.2e-13 49.3 0.3 1e-12 48.0 0.3 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.16 KXS16763.1 - 0.00011 22.4 0.0 0.0007 19.8 0.0 2.3 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 KXS16763.1 - 0.00074 20.1 0.8 0.016 15.8 1.0 3.1 2 1 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II ENTH PF01417.20 KXS16765.1 - 1.1e-48 164.5 0.0 2.2e-48 163.4 0.0 1.6 2 0 0 2 2 2 1 ENTH domain ANTH PF07651.16 KXS16765.1 - 4.2e-06 26.0 0.0 7.8e-06 25.1 0.0 1.6 1 1 0 1 1 1 1 ANTH domain UIM PF02809.20 KXS16765.1 - 1.1e-05 25.0 11.7 0.0019 18.0 4.7 2.9 2 0 0 2 2 2 2 Ubiquitin interaction motif PPTA PF01239.22 KXS16766.1 - 4.4e-46 153.3 11.4 5.5e-10 38.6 0.3 5.4 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat Sec7_N PF12783.7 KXS16766.1 - 0.094 12.6 0.1 0.5 10.3 0.0 2.2 2 1 0 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal DNA_pol_B PF00136.21 KXS16767.1 - 1e-147 492.6 2.6 1.5e-147 492.1 2.6 1.3 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 KXS16767.1 - 1.8e-81 273.9 0.0 3.1e-81 273.1 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 KXS16767.1 - 1.7e-18 66.8 7.3 3.5e-18 65.8 7.3 1.5 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.13 KXS16767.1 - 4.6e-05 22.5 1.1 0.00024 20.1 0.1 2.2 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral RNase_H_2 PF13482.6 KXS16767.1 - 0.0063 16.5 1.2 0.051 13.6 0.2 2.7 2 1 0 2 2 2 1 RNase_H superfamily Coa1 PF08695.10 KXS16768.1 - 5.1e-21 74.6 0.0 5.9e-21 74.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 CH_2 PF06294.11 KXS16769.1 - 2.6e-12 46.7 0.0 7e-12 45.3 0.0 1.8 1 0 0 1 1 1 1 CH-like domain in sperm protein ADK PF00406.22 KXS16769.1 - 0.0008 19.5 0.0 4.6 7.3 0.0 3.5 3 0 0 3 3 3 2 Adenylate kinase Hydin_ADK PF17213.3 KXS16769.1 - 0.0084 16.4 0.0 0.0084 16.4 0.0 4.7 3 1 1 4 4 4 1 Hydin Adenylate kinase-like domain CH PF00307.31 KXS16769.1 - 0.014 15.6 0.0 0.039 14.1 0.0 1.8 1 0 0 1 1 1 0 Calponin homology (CH) domain TetR_C_22 PF17928.1 KXS16769.1 - 0.23 11.8 2.6 0.52 10.7 0.6 2.5 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain AAA PF00004.29 KXS16770.1 - 1.6e-37 128.9 0.0 3.3e-37 127.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KXS16770.1 - 1.1e-12 47.6 0.1 2.7e-12 46.3 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain zf-C3HC4 PF00097.25 KXS16770.1 - 3.4e-10 39.6 1.9 6.1e-10 38.8 1.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXS16770.1 - 6.9e-09 35.4 3.4 1.9e-08 34.0 3.5 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KXS16770.1 - 9.7e-09 35.0 1.9 1.6e-08 34.3 1.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXS16770.1 - 1.4e-08 34.6 1.0 1.4e-08 34.6 1.0 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 KXS16770.1 - 2.9e-08 33.9 5.5 4.9e-08 33.2 5.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KXS16770.1 - 2.7e-07 30.4 2.5 4.5e-07 29.7 2.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KXS16770.1 - 9.4e-06 25.4 3.6 1.6e-05 24.7 3.6 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 RuvB_N PF05496.12 KXS16770.1 - 2.9e-05 23.8 0.0 5.3e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Vps4_C PF09336.10 KXS16770.1 - 4.6e-05 23.3 0.1 0.00011 22.2 0.1 1.6 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain zf-C3HC4_4 PF15227.6 KXS16770.1 - 0.00011 22.3 5.5 0.00023 21.2 5.2 1.8 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 KXS16770.1 - 0.0003 21.0 3.4 0.00065 19.9 3.4 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain AAA_24 PF13479.6 KXS16770.1 - 0.00084 19.1 0.0 0.002 17.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KXS16770.1 - 0.00097 19.4 0.6 0.024 14.9 0.2 2.6 2 1 0 2 2 1 1 AAA domain AAA_5 PF07728.14 KXS16770.1 - 0.0016 18.4 0.1 0.014 15.4 0.1 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 KXS16770.1 - 0.0022 17.4 0.1 0.0049 16.3 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 KXS16770.1 - 0.0027 18.1 0.0 0.0064 16.9 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_2 PF07724.14 KXS16770.1 - 0.0038 17.4 0.0 0.0066 16.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Baculo_IE-1 PF05290.11 KXS16770.1 - 0.0039 17.1 1.2 0.0072 16.3 1.2 1.3 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) AAA_33 PF13671.6 KXS16770.1 - 0.011 15.9 0.0 0.023 14.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 KXS16770.1 - 0.014 14.6 0.0 0.023 13.9 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_14 PF13173.6 KXS16770.1 - 0.032 14.3 0.0 0.22 11.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 KXS16770.1 - 0.041 13.6 0.0 0.071 12.8 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein zf-ANAPC11 PF12861.7 KXS16770.1 - 0.043 13.9 0.7 0.087 12.9 0.7 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger AAA_18 PF13238.6 KXS16770.1 - 0.048 14.2 0.3 0.25 11.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain DDE_Tnp_IS1595 PF12762.7 KXS16770.1 - 0.074 13.1 0.1 2.9 7.9 0.0 2.4 2 0 0 2 2 2 0 ISXO2-like transposase domain RNA_helicase PF00910.22 KXS16770.1 - 0.1 13.0 0.0 0.21 12.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase U-box PF04564.15 KXS16770.1 - 0.14 12.4 0.0 0.41 10.9 0.0 1.8 1 0 0 1 1 1 0 U-box domain ATPase PF06745.13 KXS16770.1 - 0.14 11.5 0.0 5.5 6.3 0.1 2.2 1 1 1 2 2 2 0 KaiC NACHT PF05729.12 KXS16770.1 - 0.18 11.7 0.1 0.34 10.8 0.1 1.4 1 0 0 1 1 1 0 NACHT domain Parvo_NS1 PF01057.17 KXS16770.1 - 0.19 10.8 0.1 0.29 10.2 0.1 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 PhoH PF02562.16 KXS16770.1 - 0.19 11.2 0.0 0.35 10.3 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein EVI2A PF05399.11 KXS16770.1 - 1.1 8.8 3.7 0.32 10.6 0.2 1.8 2 0 0 2 2 2 0 Ectropic viral integration site 2A protein (EVI2A) zf-RING_4 PF14570.6 KXS16770.1 - 1.3 8.9 4.7 2.5 8.0 4.7 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain LTV PF04180.14 KXS16771.1 - 4.5e-42 145.1 49.0 1.7e-31 110.4 20.6 5.0 2 1 2 4 4 4 3 Low temperature viability protein Ion_trans PF00520.31 KXS16772.1 - 3.1e-24 85.5 10.3 3.9e-24 85.2 10.3 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 KXS16772.1 - 2.7e-11 43.3 7.7 7.6e-11 41.8 7.3 2.0 1 1 0 1 1 1 1 Ion channel IRK PF01007.20 KXS16772.1 - 0.087 12.6 1.1 0.15 11.8 1.1 1.3 1 0 0 1 1 1 0 Inward rectifier potassium channel transmembrane domain Sigma_reg_N PF13800.6 KXS16772.1 - 0.31 11.4 0.9 6.7 7.1 0.1 2.4 2 0 0 2 2 2 0 Sigma factor regulator N-terminal HemY_N PF07219.13 KXS16772.1 - 1.2 9.3 8.4 8.1 6.7 4.4 3.4 2 1 0 2 2 2 0 HemY protein N-terminus ALMT PF11744.8 KXS16772.1 - 5 5.9 8.7 2.1 7.1 4.9 1.8 1 1 1 2 2 2 0 Aluminium activated malate transporter DUF2207 PF09972.9 KXS16772.1 - 9 4.9 8.0 0.72 8.5 1.9 1.9 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) Peptidase_A24 PF01478.18 KXS16772.1 - 9.6 6.7 8.6 0.5 10.8 2.5 1.9 2 0 0 2 2 2 0 Type IV leader peptidase family AhpC-TSA_2 PF13911.6 KXS16773.1 - 5.9e-12 45.7 0.0 7.8e-12 45.3 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 KXS16773.1 - 5.2e-05 23.2 0.0 6.3e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KXS16773.1 - 0.00042 20.1 0.0 0.00053 19.7 0.0 1.3 1 1 0 1 1 1 1 Redoxin DUF4407 PF14362.6 KXS16774.1 - 0.00052 19.5 14.6 0.00052 19.5 14.6 6.7 1 1 4 6 6 6 1 Domain of unknown function (DUF4407) Fez1 PF06818.15 KXS16774.1 - 0.0039 17.7 6.7 0.0039 17.7 6.7 6.1 2 2 2 5 5 5 2 Fez1 MSG PF02349.15 KXS16774.1 - 0.0071 16.5 0.5 0.021 15.0 0.5 1.8 1 0 0 1 1 1 1 Major surface glycoprotein HEPN_RiboL-PSP PF18735.1 KXS16774.1 - 0.041 13.8 0.6 0.12 12.3 0.6 1.8 1 0 0 1 1 1 0 RiboL-PSP-HEPN SepF PF04472.12 KXS16774.1 - 1 9.7 7.8 24 5.3 0.2 4.2 4 0 0 4 4 4 0 Cell division protein SepF Tropomyosin_1 PF12718.7 KXS16774.1 - 9.5 6.4 115.1 0.027 14.6 2.9 9.7 4 2 5 9 9 9 0 Tropomyosin like SAGA-Tad1 PF12767.7 KXS16775.1 - 1.6e-23 83.7 0.0 2.1e-17 63.6 0.0 2.8 2 1 1 3 3 3 2 Transcriptional regulator of RNA polII, SAGA, subunit HrpB1_HrpK PF09613.10 KXS16775.1 - 0.067 12.8 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB1_HrpK) Exo_endo_phos PF03372.23 KXS16778.1 - 1.1e-07 31.7 3.0 9.5e-07 28.6 3.0 2.1 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Pex14_N PF04695.13 KXS16779.1 - 1 10.0 5.6 1.4 9.5 5.6 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region zf-H2C2_2 PF13465.6 KXS16780.1 - 2.7e-09 37.0 8.5 1.1e-07 32.0 0.3 2.8 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 KXS16780.1 - 2.3e-06 27.8 12.0 0.0025 18.2 0.4 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXS16780.1 - 1.3e-05 25.6 10.8 0.14 13.0 0.8 3.3 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KXS16780.1 - 0.0031 17.8 1.2 0.0056 17.0 1.2 1.4 1 1 0 1 1 1 1 C2H2-type zinc ribbon HalOD2 PF18547.1 KXS16780.1 - 0.0074 16.2 0.2 0.69 9.9 0.0 2.4 2 0 0 2 2 2 1 Halobacterial output domain 2 IBR PF01485.21 KXS16780.1 - 0.025 14.8 2.1 0.025 14.8 0.8 1.6 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain RNA_POL_M_15KD PF02150.16 KXS16780.1 - 0.07 13.0 0.3 13 5.7 0.0 2.4 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit zf-RAG1 PF10426.9 KXS16780.1 - 0.18 12.0 0.3 0.53 10.5 0.0 1.9 2 0 0 2 2 2 0 Recombination-activating protein 1 zinc-finger domain zf-C2H2_6 PF13912.6 KXS16780.1 - 0.33 11.0 0.4 0.33 11.0 0.4 3.7 4 0 0 4 4 4 0 C2H2-type zinc finger zf-LYAR PF08790.11 KXS16780.1 - 0.33 10.9 8.2 4.2 7.4 0.1 3.4 3 1 0 3 3 3 0 LYAR-type C2HC zinc finger zf-C2HE PF16278.5 KXS16780.1 - 1.6 9.2 6.3 1.3 9.5 3.8 2.2 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger Synthase_beta PF11421.8 KXS16781.1 - 0.42 11.3 1.5 0.44 11.3 0.1 1.8 2 0 0 2 2 2 0 ATP synthase F1 beta subunit Ank_3 PF13606.6 KXS16782.1 - 3.3e-05 24.0 0.1 0.038 14.5 0.0 3.4 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 KXS16782.1 - 0.035 14.7 0.0 0.97 10.1 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXS16782.1 - 0.14 12.7 0.0 9.5 6.9 0.0 2.5 3 0 0 3 3 3 0 Ankyrin repeats (3 copies) SH3_9 PF14604.6 KXS16783.1 - 8.8e-07 28.7 0.0 2.2e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXS16783.1 - 2.3e-05 23.9 0.0 5.6e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 SH3 domain CENP-F_leu_zip PF10473.9 KXS16783.1 - 0.0011 19.0 6.0 0.0011 19.0 6.0 1.9 2 0 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fez1 PF06818.15 KXS16783.1 - 0.039 14.4 1.5 0.087 13.3 1.5 1.5 1 0 0 1 1 1 0 Fez1 FPP PF05911.11 KXS16783.1 - 0.043 12.0 1.9 0.058 11.6 1.9 1.1 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil TMF_TATA_bd PF12325.8 KXS16783.1 - 0.56 10.4 4.3 0.73 10.1 1.9 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Rootletin PF15035.6 KXS16783.1 - 1.8 8.5 7.5 0.24 11.4 3.1 1.7 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion SRP-alpha_N PF04086.13 KXS16783.1 - 2.3 8.1 8.5 3.7 7.4 8.5 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal MccV PF17508.2 KXS16784.1 - 0.097 13.2 0.3 0.097 13.2 0.3 2.9 3 0 0 3 3 3 0 Microcin V bacteriocin Pkinase_Tyr PF07714.17 KXS16785.1 - 4.3e-40 137.6 0.0 5.8e-40 137.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXS16785.1 - 2.6e-38 131.9 0.0 3.7e-38 131.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain LRR_6 PF13516.6 KXS16785.1 - 3.5e-23 79.6 23.6 0.046 13.8 0.0 13.8 14 0 0 14 14 14 6 Leucine Rich repeat LRR_4 PF12799.7 KXS16785.1 - 8.6e-07 29.2 11.5 1 9.9 0.0 7.1 4 3 3 8 8 8 3 Leucine Rich repeats (2 copies) RIO1 PF01163.22 KXS16785.1 - 0.0018 17.9 0.0 0.0046 16.6 0.0 1.6 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.14 KXS16785.1 - 0.0052 16.2 0.0 0.017 14.5 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family m04gp34like PF12216.8 KXS16787.1 - 0.29 10.7 1.5 0.7 9.4 0.0 2.0 2 0 0 2 2 2 0 Immune evasion protein 2TM PF13239.6 KXS16787.1 - 0.59 10.5 6.4 1.3 9.3 1.0 2.6 2 0 0 2 2 2 0 2TM domain TAP_C PF03943.13 KXS16788.1 - 2e-13 49.7 0.1 4.3e-13 48.7 0.1 1.6 1 0 0 1 1 1 1 TAP C-terminal domain RRM_9 PF18444.1 KXS16788.1 - 3.6e-10 39.6 0.1 1.7e-09 37.4 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif NTF2 PF02136.20 KXS16788.1 - 3.7e-07 30.7 0.0 8.2e-06 26.4 0.0 2.3 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain LRR_8 PF13855.6 KXS16788.1 - 0.00099 18.8 3.7 0.0026 17.5 3.7 1.8 1 0 0 1 1 1 1 Leucine rich repeat LRR_9 PF14580.6 KXS16788.1 - 0.0023 17.5 0.4 0.027 14.0 0.6 2.0 1 1 1 2 2 2 1 Leucine-rich repeat LRR_4 PF12799.7 KXS16788.1 - 2.1 8.9 9.6 1.1 9.8 3.2 2.5 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) MARVEL PF01284.23 KXS16789.1 - 1.3e-07 31.7 8.9 1.9e-07 31.2 8.9 1.2 1 0 0 1 1 1 1 Membrane-associating domain HVSL PF09749.9 KXS16790.1 - 1.8e-31 109.5 0.0 2.4e-31 109.1 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein 2_5_RNA_ligase2 PF13563.6 KXS16790.1 - 0.0039 17.1 0.0 0.0078 16.1 0.0 1.4 1 1 0 1 1 1 1 2'-5' RNA ligase superfamily Na_Ca_ex PF01699.24 KXS16791.1 - 6.5e-36 123.6 39.1 2.1e-22 79.7 18.3 2.9 3 0 0 3 3 3 2 Sodium/calcium exchanger protein Shisa PF13908.6 KXS16791.1 - 0.018 15.3 0.3 1.7 8.8 0.1 2.3 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Ribosomal_L28e PF01778.17 KXS16793.1 - 6.4e-41 139.7 2.2 6.4e-41 139.7 2.2 1.6 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.14 KXS16793.1 - 8.2e-22 77.7 21.4 8.2e-22 77.7 21.4 2.5 1 1 1 2 2 2 1 Mak16 protein C-terminal region Nop14 PF04147.12 KXS16793.1 - 0.00094 17.5 20.9 0.0012 17.2 20.9 1.1 1 0 0 1 1 1 1 Nop14-like family BUD22 PF09073.10 KXS16793.1 - 0.0012 18.3 17.1 0.0016 17.9 17.1 1.2 1 0 0 1 1 1 1 BUD22 SGT1 PF07093.11 KXS16793.1 - 0.58 8.5 11.0 0.92 7.9 11.0 1.2 1 0 0 1 1 1 0 SGT1 protein CDC45 PF02724.14 KXS16793.1 - 1 7.6 16.4 2 6.6 16.4 1.4 1 0 0 1 1 1 0 CDC45-like protein UPF0240 PF06784.11 KXS16793.1 - 1.2 9.2 15.3 0.79 9.8 0.3 3.0 1 1 1 3 3 3 0 Uncharacterised protein family (UPF0240) Cwf_Cwc_15 PF04889.12 KXS16793.1 - 2.7 7.6 20.5 5.3 6.7 20.5 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein BNIP2 PF12496.8 KXS16793.1 - 5.8 7.3 14.4 4.3 7.8 12.6 1.7 2 0 0 2 2 2 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 CobT PF06213.12 KXS16793.1 - 7.5 5.8 23.0 12 5.1 23.0 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Thioredoxin PF00085.20 KXS16794.1 - 4.4e-15 55.5 0.0 6.2e-15 55.1 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 KXS16794.1 - 7.7e-08 32.0 0.0 1e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 KXS16794.1 - 0.035 14.6 0.1 0.079 13.4 0.1 1.5 1 1 0 1 1 1 0 Thioredoxin-like domain TraF PF13728.6 KXS16794.1 - 0.11 12.4 0.1 0.26 11.1 0.1 1.6 1 1 0 1 1 1 0 F plasmid transfer operon protein Thioredoxin_8 PF13905.6 KXS16794.1 - 0.19 12.1 0.0 0.65 10.4 0.0 1.8 1 1 1 2 2 2 0 Thioredoxin-like Snapin_Pallidin PF14712.6 KXS16796.1 - 0.00034 21.0 0.0 0.00043 20.6 0.0 1.1 1 0 0 1 1 1 1 Snapin/Pallidin Rhodanese PF00581.20 KXS16797.1 - 8.9e-17 61.6 0.0 1.2e-16 61.2 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain DUF5427 PF10310.9 KXS16799.1 - 0.022 13.8 6.7 0.38 9.6 3.9 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5427) GGDEF_2 PF17853.1 KXS16799.1 - 0.19 12.0 1.7 1.4 9.2 0.2 2.9 3 0 0 3 3 3 0 GGDEF-like domain DUF719 PF05334.13 KXS16799.1 - 0.22 11.7 2.8 0.5 10.5 2.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF719) K_channel_TID PF07941.11 KXS16799.1 - 8.9 6.9 9.0 0.9 10.0 0.5 2.9 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain DIOX_N PF14226.6 KXS16800.1 - 1.6e-20 74.0 0.0 2.7e-20 73.3 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KXS16800.1 - 1e-11 45.2 0.0 2.2e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PRIMA1 PF16101.5 KXS16800.1 - 0.33 11.0 3.6 0.79 9.8 3.6 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Ribosomal_S16 PF00886.19 KXS16801.1 - 2e-25 88.6 0.3 3.9e-25 87.7 0.2 1.5 2 0 0 2 2 2 1 Ribosomal protein S16 CPSF_A PF03178.15 KXS16802.1 - 8.1e-87 291.5 0.0 2e-86 290.2 0.0 1.7 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.9 KXS16802.1 - 2e-16 59.7 0.0 1.7e-08 33.6 0.0 2.9 2 1 0 2 2 2 2 Mono-functional DNA-alkylating methyl methanesulfonate N-term TMEM234 PF10639.9 KXS16803.1 - 3.1e-32 111.0 1.8 3.6e-32 110.8 1.8 1.0 1 0 0 1 1 1 1 Putative transmembrane family 234 EamA PF00892.20 KXS16803.1 - 4.9e-10 39.7 12.1 1.4e-08 35.0 12.1 2.0 1 1 0 1 1 1 1 EamA-like transporter family EmrE PF13536.6 KXS16803.1 - 0.00079 19.1 1.9 0.0011 18.6 1.9 1.3 1 0 0 1 1 1 1 Putative multidrug resistance efflux transporter TPT PF03151.16 KXS16803.1 - 0.0028 17.1 0.4 0.0038 16.6 0.4 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family Multi_Drug_Res PF00893.19 KXS16803.1 - 0.0042 17.7 3.5 0.0055 17.3 2.5 1.7 1 1 1 2 2 2 1 Small Multidrug Resistance protein zf-C3HC4_3 PF13920.6 KXS16804.1 - 6.7e-13 48.3 10.6 9.4e-13 47.8 10.6 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KXS16804.1 - 0.00033 20.4 11.4 0.00055 19.7 11.4 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 GIDE PF12483.8 KXS16804.1 - 0.00092 18.6 0.3 0.89 8.9 0.0 3.0 3 0 0 3 3 3 2 E3 Ubiquitin ligase zf-RING_5 PF14634.6 KXS16804.1 - 0.0043 17.0 10.6 0.0063 16.5 10.6 1.2 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 KXS16804.1 - 0.016 15.5 12.0 0.025 14.9 12.0 1.3 1 0 0 1 1 1 0 Ring finger domain ArfGap PF01412.18 KXS16804.1 - 2.2 8.4 4.0 4.3 7.4 4.0 1.4 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf zf-P11 PF03854.14 KXS16804.1 - 2.5 7.8 8.2 5.1 6.8 8.2 1.5 1 0 0 1 1 1 0 P-11 zinc finger LapA_dom PF06305.11 KXS16804.1 - 7.6 6.4 8.4 0.86 9.5 2.1 2.3 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain zf-NOSIP PF15906.5 KXS16805.1 - 1.6e-07 31.3 0.3 4.2e-07 30.0 0.3 1.8 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein zf-RING_5 PF14634.6 KXS16805.1 - 2.5e-06 27.3 7.1 2.5e-06 27.3 7.1 2.9 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KXS16805.1 - 2.4e-05 24.1 20.9 0.00063 19.5 7.9 2.7 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXS16805.1 - 9.7e-05 22.6 20.2 0.00011 22.4 7.3 2.6 2 0 0 2 2 2 1 Ring finger domain Prok-RING_4 PF14447.6 KXS16805.1 - 0.00046 20.0 24.1 0.0014 18.5 9.5 3.2 2 1 1 3 3 3 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 KXS16805.1 - 0.0008 19.2 22.2 0.0019 18.0 8.9 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXS16805.1 - 0.0064 16.3 8.6 0.0064 16.3 8.6 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXS16805.1 - 0.14 12.2 17.9 0.71 9.9 5.5 2.9 2 1 0 2 2 2 0 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KXS16805.1 - 1.7 8.9 19.3 5.6 7.2 4.1 3.4 2 1 1 3 3 3 0 zinc finger of C3HC4-type, RING Ima1_N PF09779.9 KXS16805.1 - 5.1 8.0 12.6 37 5.2 11.6 2.5 1 1 0 1 1 1 0 Ima1 N-terminal domain Rtf2 PF04641.12 KXS16805.1 - 5.2 6.4 19.2 0.027 13.8 3.7 2.5 2 1 1 3 3 3 0 Rtf2 RING-finger Rad50_zn_hook PF04423.14 KXS16805.1 - 6.9 6.6 9.8 1.9 8.4 0.3 3.2 1 1 2 3 3 3 0 Rad50 zinc hook motif zf-RING_10 PF16685.5 KXS16805.1 - 8.8 6.5 16.2 0.99 9.6 7.1 2.4 2 0 0 2 2 2 0 zinc RING finger of MSL2 DUF2431 PF10354.9 KXS16806.1 - 8.7e-27 94.4 0.0 3.3e-23 82.8 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF2431) zf-C2H2 PF00096.26 KXS16806.1 - 1.6e-06 28.2 6.6 0.0033 17.8 0.1 4.5 4 0 0 4 4 4 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXS16806.1 - 9.9e-05 22.9 9.4 0.0061 17.3 0.1 4.7 4 0 0 4 4 4 1 C2H2-type zinc finger DNA_ligase_ZBD PF03119.16 KXS16806.1 - 0.011 15.7 0.5 0.029 14.4 0.5 1.8 1 0 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain zf_UBZ PF18439.1 KXS16806.1 - 0.027 14.1 0.8 6.4 6.5 0.1 2.7 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-ribbon_3 PF13248.6 KXS16806.1 - 0.033 13.6 3.9 3.8 7.0 0.1 2.9 3 0 0 3 3 3 0 zinc-ribbon domain zf-C2H2_11 PF16622.5 KXS16806.1 - 0.057 13.2 0.2 0.17 11.7 0.2 1.8 1 0 0 1 1 1 0 zinc-finger C2H2-type Zn-ribbon_8 PF09723.10 KXS16806.1 - 0.064 13.4 1.4 4.6 7.4 0.0 3.1 3 0 0 3 3 3 0 Zinc ribbon domain zf-C2HE PF16278.5 KXS16806.1 - 0.071 13.6 0.0 0.25 11.8 0.0 1.9 1 0 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger Ribosomal_S27e PF01667.17 KXS16806.1 - 0.16 11.7 0.5 2.7 7.8 0.1 2.4 2 0 0 2 2 2 0 Ribosomal protein S27 zf-H2C2_2 PF13465.6 KXS16806.1 - 0.62 10.6 10.9 9.4 6.9 0.1 5.2 5 1 0 5 5 5 0 Zinc-finger double domain zf-C2H2_6 PF13912.6 KXS16806.1 - 2 8.5 5.4 2.2 8.4 0.4 2.9 3 0 0 3 3 3 0 C2H2-type zinc finger Mitoc_mL59 PF18126.1 KXS16807.1 - 9.3e-09 35.7 7.3 1.8e-08 34.7 7.3 1.6 1 1 0 1 1 1 1 Mitochondrial ribosomal protein mL59 PDT PF00800.18 KXS16809.1 - 1.2e-55 188.1 0.0 1.6e-55 187.7 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.25 KXS16809.1 - 1.2e-12 47.3 0.0 2.2e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 ACT domain LD_cluster3 PF18180.1 KXS16809.1 - 0.049 13.3 0.1 0.096 12.3 0.1 1.4 1 0 0 1 1 1 0 SLOG cluster3 family DUF3439 PF11921.8 KXS16809.1 - 0.63 10.0 6.7 0.77 9.7 3.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) DNA_pol_A PF00476.20 KXS16810.1 - 1.4e-107 360.0 0.0 2.1e-107 359.5 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family A DEAD PF00270.29 KXS16810.1 - 1.3e-16 60.9 0.0 2.9e-16 59.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXS16810.1 - 1.4e-10 41.5 0.0 1.2e-09 38.5 0.0 2.6 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXS16810.1 - 7.5e-08 32.6 0.0 1.4e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2631 PF10939.8 KXS16810.1 - 0.037 13.8 0.5 0.1 12.5 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2631) Hist_deacetyl PF00850.19 KXS16811.1 - 2.8e-85 286.5 0.0 3.7e-85 286.1 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain UCH_1 PF13423.6 KXS16812.1 - 4.9e-93 312.2 0.1 6.4e-93 311.8 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.24 KXS16812.1 - 9.6e-22 78.3 0.0 1.6e-21 77.5 0.0 1.4 1 0 0 1 1 1 1 Exonuclease UCH PF00443.29 KXS16812.1 - 2.4e-08 33.8 0.0 1.3e-07 31.4 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ANAPC4_WD40 PF12894.7 KXS16812.1 - 0.0062 16.8 0.1 36 4.8 0.0 4.3 2 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain OPT PF03169.15 KXS16813.1 - 1.3e-161 539.3 42.8 1.5e-161 539.1 42.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF3638 PF12340.8 KXS16815.1 - 2.6e-51 174.1 0.3 6.4e-51 172.9 0.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.8 KXS16815.1 - 6.3e-12 44.7 0.1 1.3e-11 43.7 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) FAD_binding_3 PF01494.19 KXS16816.1 - 3.2e-07 29.9 0.0 8.1e-05 22.0 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain PolyA_pol PF01743.20 KXS16817.1 - 1.6e-25 90.0 0.8 2.4e-25 89.4 0.1 1.6 2 0 0 2 2 2 1 Poly A polymerase head domain tRNA_NucTran2_2 PF13735.6 KXS16818.1 - 0.0072 16.3 0.0 0.011 15.8 0.0 1.3 1 0 0 1 1 1 1 tRNA nucleotidyltransferase domain 2 putative WD-3 PF09765.9 KXS16818.1 - 0.18 11.1 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 WD-repeat region Ank_3 PF13606.6 KXS16819.1 - 1.2e-05 25.2 0.2 0.62 10.8 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 KXS16819.1 - 1.7e-05 25.3 0.1 0.0018 18.8 0.0 2.9 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXS16819.1 - 6.3e-05 23.2 0.1 1.6 9.2 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXS16819.1 - 0.00015 22.3 0.1 0.8 10.4 0.1 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KXS16819.1 - 0.00018 21.8 0.2 1.4 9.5 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat zf-Nse PF11789.8 KXS16820.1 - 6e-10 38.8 0.2 1.2e-09 37.9 0.2 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-MIZ PF02891.20 KXS16820.1 - 1e-09 37.9 0.2 1.8e-09 37.2 0.2 1.3 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger IDO PF01231.18 KXS16821.1 - 2.5e-44 151.8 0.0 3e-44 151.5 0.0 1.1 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase Sulfatase PF00884.23 KXS16822.1 - 4.7e-79 266.0 0.0 5.8e-79 265.7 0.0 1.1 1 0 0 1 1 1 1 Sulfatase DUF229 PF02995.17 KXS16822.1 - 0.00062 18.5 0.0 0.0049 15.5 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF229) Sulfatase_C PF14707.6 KXS16822.1 - 0.012 16.3 0.0 0.74 10.6 0.0 2.4 1 1 0 1 1 1 0 C-terminal region of aryl-sulfatase DUF1501 PF07394.12 KXS16822.1 - 0.017 14.2 0.0 0.031 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) DUF4994 PF16385.5 KXS16822.1 - 0.15 12.0 0.3 0.61 10.0 0.3 1.9 1 1 0 1 1 1 0 Domain of unknown function zf-RING_2 PF13639.6 KXS16823.1 - 1.3e-07 31.8 7.6 3.2e-07 30.6 7.6 1.7 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KXS16823.1 - 7.7e-07 29.3 6.2 2.6e-06 27.6 6.2 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KXS16823.1 - 2.1e-05 24.3 6.0 5.2e-05 23.0 6.0 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXS16823.1 - 0.001 19.1 4.6 0.0035 17.3 4.6 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KXS16823.1 - 0.002 18.0 4.5 0.0041 16.9 4.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KXS16823.1 - 0.0057 16.7 3.3 0.012 15.6 3.3 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 KXS16823.1 - 0.0058 16.8 1.6 0.0058 16.8 1.6 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING FYVE PF01363.21 KXS16823.1 - 0.02 15.0 3.5 0.044 13.9 3.5 1.6 1 0 0 1 1 1 0 FYVE zinc finger UPF0242 PF06785.11 KXS16823.1 - 0.045 13.8 0.6 0.071 13.2 0.6 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus ZapB PF06005.12 KXS16823.1 - 0.056 13.9 8.8 0.12 12.8 8.8 1.5 1 1 0 1 1 1 0 Cell division protein ZapB DUF1363 PF07101.11 KXS16823.1 - 0.061 13.6 0.1 0.17 12.2 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1363) zf-C3HC4_2 PF13923.6 KXS16823.1 - 0.066 13.1 6.5 0.21 11.4 6.5 2.0 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DivIVA PF05103.13 KXS16823.1 - 0.24 11.5 5.8 0.41 10.7 5.8 1.3 1 0 0 1 1 1 0 DivIVA protein zf-Nse PF11789.8 KXS16823.1 - 0.25 11.2 1.4 0.88 9.4 1.4 2.0 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_5 PF14634.6 KXS16823.1 - 0.32 11.0 5.4 0.73 9.8 5.4 1.7 1 0 0 1 1 1 0 zinc-RING finger domain Shugoshin_N PF07558.11 KXS16823.1 - 0.43 10.5 4.6 1.4 8.9 2.3 2.3 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region Ax_dynein_light PF10211.9 KXS16823.1 - 0.66 9.9 6.9 1.1 9.2 6.9 1.2 1 0 0 1 1 1 0 Axonemal dynein light chain zf-RING_11 PF17123.5 KXS16823.1 - 0.96 9.3 5.6 2.1 8.1 5.6 1.6 1 0 0 1 1 1 0 RING-like zinc finger Prok-RING_4 PF14447.6 KXS16823.1 - 1.2 9.1 6.3 2.8 7.9 6.3 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 DUF4407 PF14362.6 KXS16823.1 - 2.7 7.3 6.2 3.9 6.8 6.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DivIC PF04977.15 KXS16823.1 - 9.3 6.1 6.6 34 4.3 0.6 2.5 1 1 1 2 2 2 0 Septum formation initiator Methyltransf_25 PF13649.6 KXS16824.1 - 2.4e-14 53.8 0.0 5.5e-14 52.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXS16824.1 - 4.6e-14 52.8 0.0 1.3e-13 51.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXS16824.1 - 4.1e-11 43.5 0.0 8.5e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXS16824.1 - 1.7e-10 40.9 0.0 2.5e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXS16824.1 - 2.1e-10 40.7 0.0 2.8e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXS16824.1 - 6.6e-06 25.6 0.0 8.6e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MetW PF07021.12 KXS16824.1 - 9.1e-05 22.1 0.0 0.00012 21.7 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW TehB PF03848.14 KXS16824.1 - 0.00012 21.6 0.0 0.00026 20.5 0.0 1.6 2 0 0 2 2 2 1 Tellurite resistance protein TehB CheR PF01739.18 KXS16824.1 - 0.0069 15.9 0.0 0.01 15.3 0.0 1.4 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain Methyltransf_32 PF13679.6 KXS16824.1 - 0.012 15.7 0.0 0.019 14.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 KXS16824.1 - 0.027 14.2 0.0 0.041 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 KXS16824.1 - 0.05 13.2 0.0 0.074 12.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Vps8 PF12816.7 KXS16825.1 - 5.2e-43 146.9 0.1 5.2e-43 146.9 0.1 2.1 3 0 0 3 3 3 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.20 KXS16825.1 - 6.8e-09 35.7 0.8 0.00011 22.1 0.0 4.6 5 0 0 5 5 5 2 Region in Clathrin and VPS ANAPC4_WD40 PF12894.7 KXS16825.1 - 0.00016 21.9 0.0 0.033 14.5 0.0 3.0 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KXS16825.1 - 0.0014 19.4 0.2 0.011 16.6 0.0 2.6 2 0 0 2 2 2 1 WD domain, G-beta repeat G-patch PF01585.23 KXS16826.1 - 3.6e-14 52.4 0.7 3.6e-14 52.4 0.7 1.9 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 KXS16826.1 - 0.0026 17.8 0.2 0.0089 16.1 0.2 2.0 1 0 0 1 1 1 1 G-patch domain DUF3585 PF12130.8 KXS16826.1 - 0.044 13.9 0.2 0.077 13.1 0.2 1.3 1 0 0 1 1 1 0 Bivalent Mical/EHBP Rab binding domain Tudor_3 PF18115.1 KXS16826.1 - 0.052 13.4 0.1 0.12 12.3 0.1 1.6 1 0 0 1 1 1 0 DNA repair protein Crb2 Tudor domain Peptidase_M20 PF01546.28 KXS16827.1 - 3.6e-20 72.5 3.3 2e-19 70.1 3.3 2.1 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KXS16827.1 - 6.5e-10 38.9 0.0 1.4e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Lactonase PF10282.9 KXS16828.1 - 6.4e-49 167.0 0.0 8.3e-49 166.7 0.0 1.1 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller RE_Bsp6I PF09504.10 KXS16828.1 - 0.16 11.5 0.0 0.25 10.9 0.0 1.2 1 0 0 1 1 1 0 Bsp6I restriction endonuclease Metallophos PF00149.28 KXS16829.1 - 2.4e-11 44.5 0.0 2.6e-06 28.1 0.0 2.4 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KXS16829.1 - 2.6e-07 31.0 0.0 0.00055 20.2 0.0 2.4 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.6 KXS16829.1 - 0.076 12.3 0.0 0.59 9.4 0.0 2.3 3 0 0 3 3 3 0 Metallophosphoesterase, calcineurin superfamily GAF_2 PF13185.6 KXS16831.1 - 4.6e-06 27.0 0.1 1.4e-05 25.4 0.1 1.8 1 1 0 1 1 1 1 GAF domain GAF PF01590.26 KXS16831.1 - 1.5e-05 25.7 0.0 2.5e-05 24.9 0.0 1.4 1 1 0 1 1 1 1 GAF domain Acyl-CoA_dh_1 PF00441.24 KXS16832.1 - 3.7e-45 153.8 0.1 8.7e-45 152.6 0.1 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KXS16832.1 - 4.5e-26 90.9 0.0 7.2e-26 90.2 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KXS16832.1 - 1.6e-22 80.2 0.0 2.5e-22 79.6 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KXS16832.1 - 1.3e-21 77.4 0.0 2.3e-21 76.5 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain zf-RING_2 PF13639.6 KXS16833.1 - 1.9e-10 40.9 14.5 3.8e-10 39.9 14.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KXS16833.1 - 1.6e-08 34.2 7.4 2.5e-08 33.5 4.9 2.2 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 KXS16833.1 - 3.4e-06 26.8 11.7 6.9e-06 25.8 11.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXS16833.1 - 4.8e-06 26.3 13.5 9.1e-06 25.4 13.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXS16833.1 - 6.3e-06 26.1 11.9 1.2e-05 25.3 8.7 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 KXS16833.1 - 2.7e-05 24.4 12.0 2.7e-05 24.4 12.0 2.1 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KXS16833.1 - 3.4e-05 23.7 11.4 6.7e-05 22.8 11.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 KXS16833.1 - 0.005 16.9 7.9 0.005 16.9 7.9 2.0 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 KXS16833.1 - 0.0065 16.3 10.7 0.015 15.1 10.7 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 KXS16833.1 - 0.11 12.7 8.0 4.4 7.5 8.0 2.7 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.6 KXS16833.1 - 0.24 11.6 12.5 1.1 9.5 12.6 2.1 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING 4HBT PF03061.22 KXS16834.1 - 0.0024 18.2 0.0 0.15 12.4 0.0 2.3 2 0 0 2 2 2 2 Thioesterase superfamily Pkinase PF00069.25 KXS16835.1 - 4.5e-46 157.4 0.0 6.4e-46 156.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS16835.1 - 1.8e-19 70.1 0.0 2.6e-19 69.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KXS16835.1 - 9.6e-06 25.1 0.4 1.5e-05 24.5 0.4 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KXS16835.1 - 3.9e-05 22.8 0.5 5.9e-05 22.2 0.5 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KXS16835.1 - 5.5e-05 23.2 0.1 0.00011 22.2 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family ELYS PF13934.6 KXS16835.1 - 0.0047 16.9 0.1 0.0075 16.3 0.1 1.3 1 0 0 1 1 1 1 Nuclear pore complex assembly Kinase-like PF14531.6 KXS16835.1 - 0.019 14.3 0.0 0.038 13.3 0.0 1.4 2 0 0 2 2 2 0 Kinase-like Pkinase_fungal PF17667.1 KXS16835.1 - 0.13 11.0 0.0 0.27 10.0 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Response_reg PF00072.24 KXS16836.1 - 1.2e-15 57.6 0.0 2.7e-15 56.5 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 KXS16836.1 - 9.2e-08 32.0 0.0 2.4e-07 30.7 0.0 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain CHASE PF03924.13 KXS16836.1 - 1.8e-07 31.3 0.0 3.4e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 CHASE domain PAS_9 PF13426.7 KXS16836.1 - 1.4e-06 28.5 0.0 5.7e-06 26.5 0.0 2.1 2 0 0 2 2 2 1 PAS domain PAS_8 PF13188.7 KXS16836.1 - 2e-05 24.5 0.0 6.3e-05 22.9 0.0 1.8 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 KXS16836.1 - 0.00062 19.7 0.0 0.006 16.6 0.0 2.4 1 1 0 1 1 1 1 PAS fold DUF4381 PF14316.6 KXS16836.1 - 0.15 12.3 0.0 0.32 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) SPOB_a PF14689.6 KXS16836.1 - 0.19 11.4 0.5 1.6 8.5 0.0 2.5 3 0 0 3 3 3 0 Sensor_kinase_SpoOB-type, alpha-helical domain zf-RING_2 PF13639.6 KXS16837.1 - 2.5e-11 43.7 7.1 2.5e-11 43.7 7.1 1.6 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KXS16837.1 - 1.7e-09 37.3 6.4 3.1e-09 36.5 6.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KXS16837.1 - 6.5e-08 32.2 2.8 6.5e-08 32.2 2.8 2.3 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 KXS16837.1 - 3.9e-07 29.8 4.3 6.6e-07 29.1 4.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXS16837.1 - 1.6e-06 28.1 1.8 1.6e-06 28.1 1.8 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KXS16837.1 - 1.7e-05 24.6 7.1 3e-05 23.8 7.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KXS16837.1 - 2.1e-05 24.7 10.1 6.9e-05 23.1 10.1 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KXS16837.1 - 0.00026 20.9 7.0 0.00045 20.1 7.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 KXS16837.1 - 0.00027 20.5 6.8 0.00043 19.8 6.8 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 KXS16837.1 - 0.0033 17.6 6.0 0.0071 16.5 6.0 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 KXS16837.1 - 0.0093 16.0 5.8 0.026 14.5 5.9 1.6 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_1 PF14446.6 KXS16837.1 - 0.02 14.8 4.6 0.039 13.9 1.2 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-Nse PF11789.8 KXS16837.1 - 0.025 14.4 3.2 0.046 13.5 3.2 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.6 KXS16837.1 - 0.028 14.3 12.3 1.3 9.0 11.2 2.5 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 PHD PF00628.29 KXS16837.1 - 0.072 13.0 7.6 0.14 12.1 7.6 1.5 1 0 0 1 1 1 0 PHD-finger zf-RING_4 PF14570.6 KXS16837.1 - 0.1 12.4 8.9 0.18 11.6 8.9 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-HC5HC2H PF13771.6 KXS16837.1 - 0.11 12.8 0.1 0.11 12.8 0.1 1.8 1 1 1 2 2 2 0 PHD-like zinc-binding domain Zn-ribbon_8 PF09723.10 KXS16837.1 - 0.19 11.9 6.2 5.5 7.2 3.4 2.5 2 0 0 2 2 2 0 Zinc ribbon domain C1_1 PF00130.22 KXS16837.1 - 0.56 10.1 5.9 1.1 9.2 5.9 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) OrfB_Zn_ribbon PF07282.11 KXS16837.1 - 0.65 10.0 3.3 0.36 10.8 0.3 2.0 1 1 1 2 2 2 0 Putative transposase DNA-binding domain GAGA PF09237.11 KXS16837.1 - 0.78 9.6 5.6 0.67 9.8 0.5 2.6 2 0 0 2 2 2 0 GAGA factor FANCL_C PF11793.8 KXS16837.1 - 0.86 9.8 9.9 4.6 7.5 8.7 2.6 2 1 0 2 2 2 0 FANCL C-terminal domain zinc_ribbon_16 PF17034.5 KXS16837.1 - 0.9 9.8 8.0 0.33 11.2 4.4 2.0 1 1 1 2 2 2 0 Zinc-ribbon like family zf-RING_2 PF13639.6 KXS16838.1 - 3.1e-08 33.8 7.4 5.7e-08 33.0 7.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KXS16838.1 - 1.9e-06 27.5 2.0 1.9e-06 27.5 2.0 1.9 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KXS16838.1 - 6.6e-06 25.9 6.3 1.3e-05 25.0 6.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXS16838.1 - 1.6e-05 24.7 4.2 2.8e-05 23.9 4.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXS16838.1 - 3.1e-05 23.8 3.9 5.3e-05 23.1 3.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 KXS16838.1 - 8.4e-05 22.8 5.6 0.00018 21.7 5.6 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KXS16838.1 - 0.00023 21.1 2.4 0.00023 21.1 2.4 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KXS16838.1 - 0.0041 17.0 6.1 0.02 14.7 6.1 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KXS16838.1 - 0.0084 16.1 2.2 0.017 15.1 2.2 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 KXS16838.1 - 0.087 12.7 3.4 0.25 11.3 3.4 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 LRR_4 PF12799.7 KXS16839.1 - 0.0057 17.0 0.0 0.012 16.0 0.0 1.5 1 0 0 1 1 1 1 Leucine Rich repeats (2 copies) ECSCR PF15820.5 KXS16840.1 - 0.08 12.8 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator WBP-1 PF11669.8 KXS16840.1 - 0.26 12.0 1.1 0.36 11.5 0.3 1.6 1 1 0 1 1 1 0 WW domain-binding protein 1 LRR_4 PF12799.7 KXS16841.1 - 2.2e-07 31.1 7.3 2.6e-05 24.5 1.9 2.5 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXS16841.1 - 0.00026 20.7 5.4 0.00055 19.7 5.4 1.6 1 0 0 1 1 1 1 Leucine rich repeat LRR_1 PF00560.33 KXS16841.1 - 0.0016 18.7 2.6 0.53 11.0 0.4 3.9 3 1 0 3 3 3 1 Leucine Rich Repeat LRR_6 PF13516.6 KXS16841.1 - 2.3 8.5 9.9 2.2 8.5 0.0 3.5 4 0 0 4 4 4 0 Leucine Rich repeat CH PF00307.31 KXS16843.1 - 7.6e-11 42.2 0.0 1.3e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain LRR_6 PF13516.6 KXS16843.1 - 0.0031 17.4 0.8 1.8 8.9 0.1 4.1 3 0 0 3 3 3 1 Leucine Rich repeat Prominin PF05478.11 KXS16844.1 - 3e-12 45.4 0.4 2.3e-09 35.9 0.3 2.1 2 0 0 2 2 2 2 Prominin Rax2 PF12768.7 KXS16844.1 - 0.0015 18.0 0.6 0.0015 18.0 0.6 3.0 2 2 1 3 3 3 1 Cortical protein marker for cell polarity DUF1218 PF06749.12 KXS16844.1 - 0.22 12.0 8.9 0.032 14.8 4.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) UPF0182 PF03699.13 KXS16844.1 - 0.28 9.3 1.4 0.43 8.7 1.4 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) Prominin PF05478.11 KXS16845.1 - 1.1e-10 40.2 5.1 1.3e-09 36.7 5.1 2.0 1 1 0 1 1 1 1 Prominin Tweety PF04906.13 KXS16845.1 - 0.00044 19.0 3.8 0.062 12.0 2.9 2.2 2 0 0 2 2 2 2 Tweety DUF1218 PF06749.12 KXS16845.1 - 0.13 12.8 4.4 0.49 11.0 4.4 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1218) Baculo_PEP_C PF04513.12 KXS16846.1 - 0.00096 19.2 9.2 0.00096 19.2 9.2 2.1 2 0 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus GCSF PF16647.5 KXS16846.1 - 0.02 14.7 1.5 1.7 8.5 0.1 2.6 2 1 0 2 2 2 0 Granulocyte colony-stimulating factor NPV_P10 PF05531.12 KXS16846.1 - 3.3 8.3 5.6 1.6 9.2 0.2 2.6 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein STI1 PF17830.1 KXS16847.1 - 7.9e-15 54.5 0.5 1.6e-07 31.2 0.0 2.6 2 1 0 2 2 2 2 STI1 domain Peptidase_M41 PF01434.18 KXS16848.1 - 7.9e-64 215.0 0.3 1.2e-63 214.5 0.3 1.2 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 KXS16848.1 - 5.8e-43 146.5 0.0 1.1e-42 145.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KXS16848.1 - 1.6e-11 43.8 0.0 3.3e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 KXS16848.1 - 4e-05 23.7 0.0 0.00031 20.8 0.0 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KXS16848.1 - 4.9e-05 23.1 0.1 0.0031 17.3 0.0 2.8 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KXS16848.1 - 4.9e-05 23.8 0.2 0.0021 18.4 0.2 2.8 1 1 0 1 1 1 1 AAA ATPase domain TIP49 PF06068.13 KXS16848.1 - 8e-05 22.0 0.0 0.00015 21.1 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain IstB_IS21 PF01695.17 KXS16848.1 - 0.00011 22.0 0.0 0.00025 20.8 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.6 KXS16848.1 - 0.00033 21.0 0.2 0.0094 16.2 0.2 2.7 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KXS16848.1 - 0.00057 20.1 0.0 0.001 19.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KXS16848.1 - 0.0043 17.6 0.0 0.0088 16.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 KXS16848.1 - 0.0074 16.4 0.0 0.02 15.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 KXS16848.1 - 0.011 15.0 0.0 0.023 13.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_28 PF13521.6 KXS16848.1 - 0.012 15.9 0.0 0.022 15.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KXS16848.1 - 0.019 14.6 0.6 0.52 9.9 0.2 2.3 1 1 1 2 2 2 0 AAA domain Mg_chelatase PF01078.21 KXS16848.1 - 0.027 13.8 0.1 0.06 12.7 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 KXS16848.1 - 0.028 14.1 0.2 0.09 12.5 0.0 2.0 2 1 0 2 2 2 0 AAA domain TsaE PF02367.17 KXS16848.1 - 0.041 13.9 0.0 0.082 12.9 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Bac_DnaA PF00308.18 KXS16848.1 - 0.067 13.0 0.0 0.19 11.5 0.0 1.8 2 0 0 2 2 1 0 Bacterial dnaA protein CPT PF07931.12 KXS16848.1 - 0.078 12.8 0.0 0.26 11.1 0.0 1.8 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Zeta_toxin PF06414.12 KXS16848.1 - 0.089 12.1 0.0 0.17 11.1 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_7 PF12775.7 KXS16848.1 - 0.12 11.9 0.0 0.85 9.1 0.0 2.3 1 1 0 1 1 1 0 P-loop containing dynein motor region Melibiase_2 PF16499.5 KXS16849.1 - 6.6e-69 232.2 1.0 7.6e-50 169.7 0.6 2.2 2 0 0 2 2 2 2 Alpha galactosidase A Melibiase PF02065.18 KXS16849.1 - 5.1e-06 25.7 0.0 1e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Melibiase Melibiase_C PF17801.1 KXS16849.1 - 3.7e-05 23.7 0.0 6.5e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Alpha galactosidase C-terminal beta sandwich domain UPF0203 PF05254.12 KXS16850.1 - 1.6e-23 82.7 0.0 2.5e-23 82.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) UCR_hinge PF02320.16 KXS16850.1 - 0.02 15.1 0.2 3.2 8.0 0.0 2.2 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein Cmc1 PF08583.10 KXS16850.1 - 0.045 13.8 0.5 9 6.4 0.0 2.1 2 0 0 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like COX17 PF05051.13 KXS16850.1 - 0.047 14.1 0.2 1.3 9.4 0.0 2.3 2 0 0 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) SRA1 PF07304.11 KXS16850.1 - 0.39 10.5 1.5 0.65 9.8 1.5 1.3 1 0 0 1 1 1 0 Steroid receptor RNA activator (SRA1) MGC-24 PF05283.11 KXS16850.1 - 1.1 9.7 4.1 1.9 9.0 4.1 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Ank_2 PF12796.7 KXS16851.1 - 8.4e-25 87.2 0.5 9.8e-13 48.5 0.1 3.1 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXS16851.1 - 3.3e-14 53.0 3.8 0.00046 20.7 0.4 4.6 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXS16851.1 - 4.7e-13 48.0 4.0 0.097 13.3 0.0 6.0 6 0 0 6 6 6 4 Ankyrin repeat Ank PF00023.30 KXS16851.1 - 4.1e-11 42.8 5.9 0.025 15.0 0.0 5.4 4 1 1 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 KXS16851.1 - 1.8e-07 31.3 9.3 0.00053 20.2 0.2 5.1 3 1 3 6 6 6 3 Ankyrin repeats (many copies) Imm_superinfect PF14373.6 KXS16851.1 - 0.17 11.8 0.0 2.3 8.2 0.0 2.8 2 0 0 2 2 2 0 Superinfection immunity protein Serpin PF00079.20 KXS16852.1 - 2e-40 139.2 0.0 2.6e-40 138.9 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) VTC PF09359.10 KXS16853.1 - 1.3e-54 185.5 0.0 2.9e-54 184.3 0.0 1.6 2 0 0 2 2 2 1 VTC domain SPX PF03105.19 KXS16853.1 - 1.7e-18 67.7 3.7 2.3e-09 37.7 0.5 3.4 3 0 0 3 3 3 2 SPX domain DUF202 PF02656.15 KXS16853.1 - 5e-12 46.1 0.7 1e-11 45.1 0.7 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF202) Proton_antipo_N PF00662.20 KXS16853.1 - 0.2 11.8 1.2 1.3 9.1 0.3 2.2 2 0 0 2 2 2 0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus DGF-1_C PF11040.8 KXS16853.1 - 2.3 8.3 12.9 7.8 6.6 0.4 3.0 3 0 0 3 3 3 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus PGA2 PF07543.12 KXS16853.1 - 4 7.4 11.0 0.77 9.7 0.6 2.4 2 0 0 2 2 2 0 Protein trafficking PGA2 Tankyrase_bdg_C PF15327.6 KXS16853.1 - 4 7.9 7.2 10 6.5 0.3 2.4 2 0 0 2 2 2 0 Tankyrase binding protein C terminal domain cNMP_binding PF00027.29 KXS16854.1 - 5e-10 39.3 0.2 1.4e-09 37.9 0.0 1.8 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain Ion_trans PF00520.31 KXS16854.1 - 0.005 16.1 1.9 0.0076 15.5 1.9 1.3 1 0 0 1 1 1 1 Ion transport protein Folate_carrier PF01770.18 KXS16855.1 - 0.016 14.0 0.2 0.044 12.5 0.0 1.7 2 0 0 2 2 2 0 Reduced folate carrier CD20 PF04103.15 KXS16855.1 - 0.041 14.0 0.1 0.071 13.2 0.1 1.3 1 0 0 1 1 1 0 CD20-like family Ephrin_rec_like PF07699.13 KXS16856.1 - 2.5e-06 27.2 5.2 2.5e-06 27.2 5.2 3.4 1 1 2 3 3 3 3 Putative ephrin-receptor like TNFR_c6 PF00020.18 KXS16856.1 - 0.026 14.9 13.4 0.035 14.5 2.4 3.2 1 1 2 3 3 3 0 TNFR/NGFR cysteine-rich region DUF2183 PF09949.9 KXS16856.1 - 0.12 12.7 0.0 0.27 11.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2183) ArgoL1 PF08699.10 KXS16857.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.5 1 1 0 1 1 1 0 Argonaute linker 1 domain SH3_9 PF14604.6 KXS16858.1 - 1.6e-09 37.4 0.1 2.8e-08 33.5 0.0 2.5 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 KXS16858.1 - 2.8e-08 33.2 0.0 5.8e-08 32.2 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KXS16858.1 - 0.01 15.5 0.0 0.022 14.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain WD40 PF00400.32 KXS16860.1 - 4.9e-17 62.0 4.0 2.9e-06 27.9 0.0 5.7 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXS16860.1 - 8.4e-07 29.2 0.0 1.4 9.3 0.0 4.2 4 0 0 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain MoaE PF02391.17 KXS16861.1 - 3.6e-38 130.3 0.0 5e-38 129.9 0.0 1.2 1 0 0 1 1 1 1 MoaE protein MerC PF03203.14 KXS16862.1 - 0.013 16.0 0.7 0.013 16.0 0.7 2.5 2 1 0 2 2 2 0 MerC mercury resistance protein TNFR_16_TM PF18422.1 KXS16862.1 - 0.014 15.4 0.2 0.014 15.4 0.2 2.7 3 0 0 3 3 3 0 Tumor necrosis factor receptor member 16 trans-membrane domain Tetraspanin PF00335.20 KXS16862.1 - 0.025 14.3 0.8 0.025 14.3 0.8 3.2 3 1 1 4 4 4 0 Tetraspanin family Trp_oprn_chp PF09534.10 KXS16862.1 - 0.044 13.6 0.1 0.07 12.9 0.1 1.3 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) PRA1 PF03208.19 KXS16862.1 - 0.071 12.7 0.4 0.071 12.7 0.4 2.4 3 1 1 4 4 4 0 PRA1 family protein Pox_A14 PF05767.12 KXS16862.1 - 0.15 12.2 12.9 1.4 9.2 0.1 4.4 3 2 1 4 4 4 0 Poxvirus virion envelope protein A14 DUF4131 PF13567.6 KXS16862.1 - 5.1 6.7 8.2 0.35 10.5 1.1 2.5 1 1 1 3 3 3 0 Domain of unknown function (DUF4131) PHO4 PF01384.20 KXS16862.1 - 6 5.8 6.5 1.2e+02 1.5 6.5 2.2 1 1 0 1 1 1 0 Phosphate transporter family Ndc1_Nup PF09531.10 KXS16862.1 - 7.9 5.0 8.4 1.6 7.4 0.3 2.1 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup adh_short_C2 PF13561.6 KXS16864.1 - 8.9e-40 136.7 0.0 1.4e-24 86.9 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXS16864.1 - 7.4e-39 133.2 0.3 3.5e-28 98.4 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 KXS16864.1 - 8.8e-05 22.5 0.0 0.00014 21.9 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXS16864.1 - 0.00019 21.0 0.1 0.0038 16.7 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXS16864.1 - 0.003 17.0 0.2 0.0082 15.6 0.0 1.7 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase GATA PF00320.27 KXS16868.1 - 2.1e-09 36.8 24.0 6.5e-06 25.7 3.8 3.0 3 0 0 3 3 3 2 GATA zinc finger Cytochrom_c3_2 PF14537.6 KXS16868.1 - 0.21 12.0 5.1 0.67 10.5 4.7 1.9 1 1 1 2 2 2 0 Cytochrome c3 ZZ PF00569.17 KXS16868.1 - 0.43 10.4 11.1 1.7 8.5 0.8 2.5 2 0 0 2 2 2 0 Zinc finger, ZZ type FYVE PF01363.21 KXS16868.1 - 2.2 8.5 7.8 9.9 6.4 1.6 2.5 2 0 0 2 2 2 0 FYVE zinc finger zf-RRPl_C4 PF17026.5 KXS16868.1 - 2.3 8.4 8.2 1.6 8.9 2.1 2.1 1 1 1 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type DZR PF12773.7 KXS16868.1 - 2.8 8.0 9.6 55 3.9 9.5 2.6 1 1 0 1 1 1 0 Double zinc ribbon Phage_Gp23 PF10669.9 KXS16870.1 - 0.026 14.8 0.0 0.064 13.6 0.0 1.5 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) GST_N_3 PF13417.6 KXS16871.1 - 0.11 12.9 0.1 0.93 9.9 0.1 2.4 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Ank_3 PF13606.6 KXS16872.1 - 3.6e-06 26.9 0.4 0.0018 18.6 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.7 KXS16872.1 - 1e-05 26.0 0.0 0.0025 18.3 0.0 2.7 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXS16872.1 - 4.3e-05 24.0 0.0 0.23 12.1 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KXS16872.1 - 6e-05 23.3 0.3 0.0037 17.6 0.1 3.0 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 KXS16872.1 - 0.00075 19.8 0.6 0.0054 17.0 0.1 2.6 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXS16873.1 - 0.00084 19.9 0.2 0.0044 17.6 0.3 2.1 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXS16873.1 - 0.0025 18.1 0.3 0.19 12.4 0.1 3.4 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 KXS16873.1 - 0.0026 18.1 1.0 0.068 13.6 0.3 3.1 3 0 0 3 3 3 1 Ankyrin repeat 7tm_1 PF00001.21 KXS16877.1 - 8.3e-16 58.1 0.9 1.2e-15 57.6 0.5 1.4 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) Pyr_redox_2 PF07992.14 KXS16878.1 - 9.3e-49 166.2 0.1 1.2e-48 165.9 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXS16878.1 - 5e-14 52.6 0.1 1.8e-12 47.6 0.2 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXS16878.1 - 0.025 14.8 0.0 6.2 7.1 0.0 2.8 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KXS16878.1 - 0.028 13.7 0.2 2.1 7.5 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pkinase PF00069.25 KXS16880.1 - 4.5e-78 262.2 0.0 5.2e-78 262.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS16880.1 - 2.8e-41 141.5 0.0 3.4e-41 141.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 KXS16880.1 - 5.8e-06 26.0 0.3 9.1e-06 25.4 0.3 1.2 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 KXS16880.1 - 7.8e-06 25.4 0.0 0.00012 21.6 0.0 2.3 1 1 1 2 2 2 1 Kinase-like APH PF01636.23 KXS16880.1 - 3e-05 24.0 0.1 0.00024 21.1 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KXS16880.1 - 0.0011 18.4 0.2 0.0022 17.4 0.2 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KXS16880.1 - 0.0017 17.4 0.1 0.0021 17.0 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain YukC PF10140.9 KXS16880.1 - 0.0037 16.2 0.1 0.005 15.7 0.1 1.1 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC Choline_kinase PF01633.20 KXS16880.1 - 0.022 14.3 0.1 0.037 13.6 0.1 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase 5_nucleotid PF05761.14 KXS16880.1 - 0.035 13.0 0.2 0.046 12.6 0.2 1.1 1 0 0 1 1 1 0 5' nucleotidase family Tubulin_3 PF14881.6 KXS16880.1 - 0.17 11.6 0.0 0.28 10.8 0.0 1.3 1 0 0 1 1 1 0 Tubulin domain Syntaxin PF00804.25 KXS16881.1 - 9.5e-05 22.2 0.7 2 8.0 0.0 3.4 3 1 0 3 3 3 3 Syntaxin SNARE PF05739.19 KXS16881.1 - 0.002 18.1 1.4 0.0036 17.3 0.5 2.0 2 0 0 2 2 2 1 SNARE domain Baculo_PEP_C PF04513.12 KXS16881.1 - 0.24 11.4 4.7 2.9 7.9 0.5 2.9 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fungus-induced PF10917.8 KXS16881.1 - 0.77 10.1 0.1 0.77 10.1 0.1 2.2 3 0 0 3 3 3 0 Fungus-induced protein FHA PF00498.26 KXS16882.1 - 3.2e-14 53.0 0.0 5.8e-14 52.2 0.0 1.5 1 0 0 1 1 1 1 FHA domain zf-RING_11 PF17123.5 KXS16882.1 - 1.4e-11 43.9 4.1 2.4e-11 43.2 4.1 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 KXS16882.1 - 1.3e-08 35.0 7.0 2.1e-08 34.4 7.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-ANAPC11 PF12861.7 KXS16882.1 - 5.3e-05 23.2 1.9 9.4e-05 22.4 1.9 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 KXS16882.1 - 0.00031 20.6 6.0 0.00048 20.0 6.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain Yop-YscD_cpl PF16697.5 KXS16882.1 - 0.00041 20.6 0.0 0.00092 19.5 0.0 1.5 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain zf-C3HC4_2 PF13923.6 KXS16882.1 - 0.00073 19.3 9.2 0.0012 18.7 9.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXS16882.1 - 0.00094 19.0 6.9 0.0015 18.4 6.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 KXS16882.1 - 0.0032 17.3 4.3 0.0054 16.6 4.3 1.4 1 0 0 1 1 1 1 PHD-finger zf-rbx1 PF12678.7 KXS16882.1 - 0.01 16.1 6.7 0.028 14.7 6.7 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 KXS16882.1 - 0.052 13.4 6.3 0.086 12.7 6.3 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXS16882.1 - 0.2 11.7 8.6 0.46 10.6 8.6 1.7 1 0 0 1 1 1 0 RING-type zinc-finger BTB PF00651.31 KXS16884.1 - 6.6e-07 29.5 0.0 1.3e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain ZapB PF06005.12 KXS16884.1 - 0.14 12.6 4.8 0.25 11.8 4.8 1.3 1 0 0 1 1 1 0 Cell division protein ZapB APG6_N PF17675.1 KXS16884.1 - 0.16 12.5 5.0 0.3 11.6 5.0 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF5495 PF17599.2 KXS16884.1 - 0.17 12.2 0.0 0.32 11.3 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5495) TSC22 PF01166.18 KXS16884.1 - 0.27 11.6 2.5 0.52 10.7 2.5 1.4 1 0 0 1 1 1 0 TSC-22/dip/bun family JIP_LZII PF16471.5 KXS16884.1 - 0.97 9.7 4.4 3.1 8.0 4.4 1.7 1 1 0 1 1 1 0 JNK-interacting protein leucine zipper II PDGLE PF13190.6 KXS16885.1 - 0.19 11.6 0.9 2.4 8.1 0.0 2.2 2 0 0 2 2 2 0 PDGLE domain zf-C2H2 PF00096.26 KXS16886.1 - 0.04 14.4 2.2 0.04 14.4 2.2 1.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_11 PF16622.5 KXS16886.1 - 0.082 12.7 2.2 0.2 11.4 2.2 1.6 1 0 0 1 1 1 0 zinc-finger C2H2-type DUF2464 PF10240.9 KXS16886.1 - 0.14 11.7 0.0 0.14 11.7 0.0 1.1 1 0 0 1 1 1 0 Multivesicular body subunit 12 zf-C2H2_4 PF13894.6 KXS16886.1 - 0.2 12.6 1.3 0.2 12.6 1.3 2.0 2 0 0 2 2 2 0 C2H2-type zinc finger Ras PF00071.22 KXS16887.1 - 3.8e-53 179.4 0.0 4.3e-53 179.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXS16887.1 - 5.8e-19 68.5 0.0 7.9e-19 68.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXS16887.1 - 8.4e-07 28.6 0.0 1.2e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KXS16887.1 - 0.033 13.7 0.0 0.23 11.0 0.0 2.1 1 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Sensor PF13796.6 KXS16888.1 - 2.4e-06 27.7 14.8 3.6e-06 27.1 14.8 1.2 1 0 0 1 1 1 1 Putative sensor UPF0259 PF06790.11 KXS16888.1 - 0.031 14.1 0.3 0.031 14.1 0.3 1.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0259) DUF2207 PF09972.9 KXS16888.1 - 1.7 7.3 11.5 1 8.0 2.9 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) WD40 PF00400.32 KXS16889.1 - 1.6e-45 152.1 24.0 1.3e-07 32.2 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXS16889.1 - 1.9e-11 44.1 0.1 0.0073 16.6 0.0 5.3 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KXS16889.1 - 0.00015 20.5 11.1 0.13 10.9 0.1 4.8 3 3 3 6 6 6 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 KXS16889.1 - 0.00032 19.6 0.0 5.3 5.7 0.0 4.2 1 1 1 3 3 3 2 Nup133 N terminal like WD40_like PF17005.5 KXS16889.1 - 0.048 13.0 0.0 31 3.7 0.0 3.4 2 2 2 4 4 4 0 WD40-like domain PQQ_3 PF13570.6 KXS16889.1 - 0.064 13.8 2.2 18 6.0 0.0 3.9 3 0 0 3 3 3 0 PQQ-like domain DUF4472 PF14739.6 KXS16890.1 - 2 9.2 6.0 0.54 11.0 0.7 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4472) Fumble PF03630.14 KXS16892.1 - 3e-82 276.4 0.1 3.5e-82 276.2 0.1 1.0 1 0 0 1 1 1 1 Fumble AlaDh_PNT_N PF05222.15 KXS16893.1 - 2e-31 109.1 0.0 2.9e-31 108.6 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.21 KXS16893.1 - 0.00092 18.6 0.0 0.0029 16.9 0.0 1.8 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Tim17 PF02466.19 KXS16894.1 - 2.6e-35 121.1 7.7 3.1e-35 120.9 7.7 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family WD40 PF00400.32 KXS16895.1 - 8.3e-36 121.4 33.6 0.00027 21.7 0.1 13.1 13 0 0 13 13 13 9 WD domain, G-beta repeat VCBS PF13517.6 KXS16895.1 - 0.00097 19.7 0.1 19 6.0 0.0 4.3 3 0 0 3 3 3 1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Ge1_WD40 PF16529.5 KXS16895.1 - 0.0033 16.5 0.0 0.55 9.1 0.0 3.7 3 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KXS16895.1 - 0.025 14.4 3.5 57 3.5 0.1 5.0 3 1 2 6 6 6 0 Eukaryotic translation initiation factor eIF2A DUF4596 PF15363.6 KXS16895.1 - 0.037 14.3 0.2 0.2 11.9 0.2 2.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4596) zf-Tim10_DDP PF02953.15 KXS16896.1 - 4.7e-20 71.0 0.6 6.9e-20 70.5 0.0 1.5 1 1 1 2 2 2 1 Tim10/DDP family zinc finger ATP-synt_E PF05680.12 KXS16897.1 - 5.3e-10 39.5 0.4 7.1e-10 39.1 0.1 1.4 1 1 0 1 1 1 1 ATP synthase E chain BSD PF03909.17 KXS16898.1 - 3.5e-12 46.1 0.8 2.9e-11 43.2 0.1 2.4 2 0 0 2 2 2 1 BSD domain EnY2 PF10163.9 KXS16898.1 - 1.5 9.3 3.9 39 4.7 0.0 3.4 3 1 1 4 4 4 0 Transcription factor e(y)2 TPR_10 PF13374.6 KXS16899.1 - 3.3e-14 52.2 10.9 3.6e-05 23.5 0.1 3.6 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 KXS16899.1 - 1.2e-12 48.0 4.1 1.2e-07 31.9 0.6 2.7 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 KXS16899.1 - 0.021 15.5 0.8 16 6.4 0.2 3.3 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 KXS16899.1 - 0.042 14.4 4.1 0.12 12.9 2.0 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_20 PF14561.6 KXS16899.1 - 0.19 12.1 5.0 1.9 8.8 1.3 2.4 1 1 2 3 3 3 0 Tetratricopeptide repeat Pkinase_Tyr PF07714.17 KXS16900.1 - 0.015 14.6 0.2 0.053 12.8 0.2 1.8 2 0 0 2 2 2 0 Protein tyrosine kinase Pkinase PF00069.25 KXS16901.1 - 0.00022 20.7 0.0 0.00026 20.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS16901.1 - 0.00077 18.8 0.0 0.00094 18.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_Tyr PF07714.17 KXS16902.1 - 0.015 14.6 0.2 0.018 14.3 0.2 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase Pkinase PF00069.25 KXS16902.1 - 0.11 11.8 0.2 0.13 11.6 0.2 1.1 1 0 0 1 1 1 0 Protein kinase domain Peptidase_M28 PF04389.17 KXS16903.1 - 4.4e-27 95.1 0.0 6.2e-27 94.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KXS16903.1 - 1.3e-05 25.1 0.3 2.7e-05 24.0 0.3 1.6 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Taxilin PF09728.9 KXS16904.1 - 4.4e-51 173.9 41.1 4.4e-51 173.9 41.1 2.0 1 1 1 2 2 2 1 Myosin-like coiled-coil protein CENP-F_leu_zip PF10473.9 KXS16904.1 - 7.4e-05 22.8 25.3 7.4e-05 22.8 25.3 3.6 2 2 2 4 4 4 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATG16 PF08614.11 KXS16904.1 - 0.00038 20.8 27.2 0.00038 20.8 27.2 2.5 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) TMF_TATA_bd PF12325.8 KXS16904.1 - 0.0049 17.1 45.3 0.79 10.0 16.4 4.3 1 1 3 4 4 4 2 TATA element modulatory factor 1 TATA binding Sp38 PF07354.12 KXS16904.1 - 0.0064 15.9 4.4 0.0064 15.9 2.4 1.8 2 0 0 2 2 2 1 Zona-pellucida-binding protein (Sp38) BRE1 PF08647.11 KXS16904.1 - 0.0095 16.0 17.6 0.0095 16.0 17.6 4.0 1 1 3 4 4 4 1 BRE1 E3 ubiquitin ligase Hamartin PF04388.12 KXS16904.1 - 0.31 9.6 25.5 0.36 9.4 25.5 1.0 1 0 0 1 1 1 0 Hamartin protein Corona_S2 PF01601.16 KXS16904.1 - 1.3 7.4 4.6 2 6.8 4.6 1.3 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein ERM PF00769.19 KXS16904.1 - 3.1 7.6 56.7 3.6 7.3 40.0 2.7 1 1 1 2 2 2 0 Ezrin/radixin/moesin family DUF4407 PF14362.6 KXS16904.1 - 3.5 6.9 39.0 12 5.2 14.4 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) HAP1_N PF04849.13 KXS16904.1 - 6.2 5.9 44.3 0.74 9.0 24.6 2.6 1 1 1 2 2 2 0 HAP1 N-terminal conserved region YabA PF06156.13 KXS16904.1 - 6.3 7.5 30.8 0.33 11.6 5.8 4.3 1 1 3 4 4 4 0 Initiation control protein YabA IPP-2 PF04979.14 KXS16905.1 - 4.3e-17 63.1 7.7 4.3e-17 63.1 7.7 2.7 2 1 0 2 2 2 1 Protein phosphatase inhibitor 2 (IPP-2) SDA1 PF05285.12 KXS16905.1 - 0.084 12.3 10.8 0.12 11.8 10.8 1.4 1 0 0 1 1 1 0 SDA1 CAF1C_H4-bd PF12265.8 KXS16906.1 - 4.9e-28 97.2 0.2 1.3e-27 95.8 0.2 1.8 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 KXS16906.1 - 4.2e-20 71.7 11.0 4.9e-05 24.0 0.1 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat eIF2A PF08662.11 KXS16906.1 - 4.6e-05 23.4 0.0 0.0012 18.8 0.0 2.6 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 KXS16906.1 - 6.6e-05 23.1 3.3 0.26 11.6 0.1 3.6 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Prenyltrans PF00432.21 KXS16907.1 - 1.8e-45 152.3 9.7 1.4e-09 37.5 1.0 5.3 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 KXS16907.1 - 0.051 12.7 0.0 0.26 10.3 0.0 1.6 1 1 1 2 2 2 0 Squalene-hopene cyclase N-terminal domain DUF155 PF02582.14 KXS16908.1 - 2.1e-55 187.5 0.1 2.6e-55 187.2 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Mst1_SARAH PF11629.8 KXS16908.1 - 0.14 12.3 0.5 0.32 11.1 0.1 1.8 2 0 0 2 2 2 0 C terminal SARAH domain of Mst1 SLAC1 PF03595.17 KXS16911.1 - 0.018 14.3 0.2 0.028 13.7 0.2 1.3 1 0 0 1 1 1 0 Voltage-dependent anion channel TROVE PF05731.11 KXS16912.1 - 1.2e-12 47.7 0.0 1.4e-12 47.4 0.0 1.0 1 0 0 1 1 1 1 TROVE domain TROVE PF05731.11 KXS16913.1 - 6.4e-05 22.2 0.1 0.00013 21.1 0.1 1.4 1 1 1 2 2 2 1 TROVE domain zf-MYND PF01753.18 KXS16914.1 - 1.1e-05 25.5 1.0 3.4e-05 23.8 1.0 1.9 1 1 0 1 1 1 1 MYND finger Meleagrin PF08189.11 KXS16914.1 - 2.2 8.0 7.1 0.56 9.9 2.3 2.3 2 0 0 2 2 2 0 Meleagrin/Cygnin family Fungal_trans PF04082.18 KXS16915.1 - 2.3e-20 72.7 0.0 4.5e-20 71.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain AT_hook PF02178.19 KXS16915.1 - 9.1 6.5 13.5 2.3 8.4 7.7 2.8 2 0 0 2 2 2 0 AT hook motif adh_short PF00106.25 KXS16917.1 - 2.4e-08 33.7 0.1 4.6e-08 32.8 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXS16917.1 - 4e-05 23.3 0.1 9.7e-05 22.0 0.1 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase PhoD PF09423.10 KXS16918.1 - 7.1e-106 354.2 0.9 8.8e-106 353.8 0.9 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase PhoD_N PF16655.5 KXS16918.1 - 3.5e-26 91.6 0.0 8e-26 90.4 0.0 1.7 1 0 0 1 1 1 1 PhoD-like phosphatase, N-terminal domain Pur_ac_phosph_N PF16656.5 KXS16918.1 - 0.00023 21.7 0.1 0.00083 19.9 0.1 2.0 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Metallophos PF00149.28 KXS16918.1 - 0.073 13.6 3.0 0.29 11.6 0.7 2.3 2 0 0 2 2 2 0 Calcineurin-like phosphoesterase DSPc PF00782.20 KXS16920.1 - 0.0017 18.2 0.0 0.0022 17.8 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PAN_4 PF14295.6 KXS16921.1 - 0.0037 17.1 0.2 0.0087 15.9 0.2 1.6 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.26 KXS16921.1 - 0.0093 15.9 0.0 0.02 14.8 0.0 1.6 1 0 0 1 1 1 1 PAN domain F-box-like PF12937.7 KXS16923.1 - 0.0086 15.9 0.1 0.022 14.6 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXS16923.1 - 0.13 12.2 0.1 0.54 10.2 0.1 2.1 2 0 0 2 2 2 0 F-box domain TMP-TENI PF02581.17 KXS16925.1 - 0.029 13.7 0.4 0.48 9.7 0.1 2.1 2 0 0 2 2 2 0 Thiamine monophosphate synthase BOP1NT PF08145.12 KXS16925.1 - 1.5 8.7 11.4 1.9 8.4 11.4 1.1 1 0 0 1 1 1 0 BOP1NT (NUC169) domain GREB1 PF15782.5 KXS16925.1 - 4.4 4.3 7.5 5.4 4.0 7.5 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Metallophos PF00149.28 KXS16927.1 - 6.1e-11 43.2 0.1 2e-10 41.5 0.1 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KXS16927.1 - 8e-06 26.1 0.0 0.0032 17.7 0.0 2.4 2 1 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.6 KXS16927.1 - 0.0034 16.8 0.0 0.012 15.0 0.0 1.7 2 0 0 2 2 2 1 Metallophosphoesterase, calcineurin superfamily Glyco_hydro_18 PF00704.28 KXS16929.1 - 9.7e-65 219.3 7.2 1.1e-64 219.1 7.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_18 PF00704.28 KXS16930.1 - 7.9e-65 219.6 4.1 9e-65 219.4 4.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Aminotran_3 PF00202.21 KXS16931.1 - 1.1e-108 363.5 0.0 1.4e-108 363.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 KXS16931.1 - 0.00039 19.7 0.0 0.00069 18.9 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Phe_ZIP PF08916.11 KXS16931.1 - 1.4 9.7 5.4 4 8.2 5.4 1.8 1 0 0 1 1 1 0 Phenylalanine zipper p450 PF00067.22 KXS16933.1 - 9e-20 70.8 0.7 1.5e-11 43.7 0.0 3.0 2 1 1 3 3 3 3 Cytochrome P450 Pkinase PF00069.25 KXS16934.1 - 1.7e-24 86.6 0.0 1.7e-12 47.3 0.0 2.7 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXS16934.1 - 3.4e-11 42.9 0.0 1.6e-05 24.3 0.0 3.8 3 1 0 3 3 3 2 Protein tyrosine kinase APH PF01636.23 KXS16934.1 - 0.00032 20.7 1.1 0.0011 19.0 0.4 1.9 1 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KXS16934.1 - 0.0027 17.1 0.0 0.0054 16.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Nudix_hydro PF18290.1 KXS16934.1 - 0.045 13.7 0.1 0.076 13.0 0.1 1.3 1 0 0 1 1 1 0 Nudix hydrolase domain FTA2 PF13095.6 KXS16934.1 - 0.082 12.5 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 AMP-binding PF00501.28 KXS16936.1 - 6.5e-75 252.3 0.0 9.6e-75 251.8 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXS16936.1 - 5.1e-24 85.1 0.4 4e-23 82.2 0.1 2.5 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 KXS16936.1 - 0.082 12.8 0.4 0.55 10.2 0.0 2.6 2 1 1 3 3 3 0 Acetyl-coenzyme A synthetase N-terminus p450 PF00067.22 KXS16937.1 - 7.1e-67 226.1 0.0 8.8e-67 225.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ENOD93 PF03386.14 KXS16937.1 - 0.13 12.2 0.1 0.26 11.2 0.1 1.5 1 0 0 1 1 1 0 Early nodulin 93 ENOD93 protein FA_desaturase PF00487.24 KXS16938.1 - 1.1e-16 61.5 14.2 1.1e-16 61.5 14.2 1.5 2 0 0 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.28 KXS16938.1 - 1.4e-11 44.4 0.0 2.8e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain KH_1 PF00013.29 KXS16939.1 - 1.6e-16 59.8 14.3 0.00012 21.8 0.1 7.5 8 0 0 8 8 8 5 KH domain SAM_1 PF00536.30 KXS16939.1 - 1.7e-09 37.9 0.0 3.8e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KXS16939.1 - 0.00016 21.7 0.0 0.00038 20.5 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PEPcase PF00311.17 KXS16941.1 - 5.3e-262 871.5 0.0 6.8e-262 871.1 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxylase PEPcase_2 PF14010.6 KXS16941.1 - 3.8e-05 22.4 0.0 8.4e-05 21.3 0.0 1.5 2 0 0 2 2 2 1 Phosphoenolpyruvate carboxylase Pkinase PF00069.25 KXS16942.1 - 2.5e-42 145.1 0.0 3.3e-34 118.5 0.0 3.3 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXS16942.1 - 1.6e-12 47.3 0.0 8.8e-12 44.8 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXS16942.1 - 0.0059 15.4 0.1 0.018 13.8 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase RIO1 PF01163.22 KXS16942.1 - 0.058 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 RIO1 family SelP_N PF04592.14 KXS16942.1 - 6.8 6.0 12.5 1.6 8.1 9.1 1.6 2 0 0 2 2 2 0 Selenoprotein P, N terminal region Dus PF01207.17 KXS16943.1 - 1.5e-29 103.1 0.0 2.6e-12 46.5 0.0 3.1 2 1 1 3 3 3 3 Dihydrouridine synthase (Dus) SelP_N PF04592.14 KXS16944.1 - 0.32 10.4 12.4 0.39 10.1 12.4 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF2796 PF10986.8 KXS16944.1 - 2.6 8.0 14.3 3.4 7.6 14.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) Ribosomal_L6 PF00347.23 KXS16945.1 - 8.5e-23 80.8 0.0 7.1e-12 45.8 0.0 3.4 2 1 1 3 3 3 2 Ribosomal protein L6 MFS_1 PF07690.16 KXS16946.1 - 2.3e-12 46.5 25.2 2.3e-12 46.5 25.2 2.4 2 1 1 3 3 3 2 Major Facilitator Superfamily MFS_2 PF13347.6 KXS16946.1 - 1.3e-09 37.2 11.2 2.2e-09 36.4 11.2 1.3 1 0 0 1 1 1 1 MFS/sugar transport protein NifU PF01106.17 KXS16949.1 - 0.11 12.6 0.9 11 6.2 0.0 2.5 2 0 0 2 2 2 0 NifU-like domain TPR_12 PF13424.6 KXS16950.1 - 4.2e-55 184.0 39.5 4.2e-13 49.4 2.4 7.1 4 2 5 9 9 8 7 Tetratricopeptide repeat TPR_10 PF13374.6 KXS16950.1 - 2.5e-48 160.7 27.2 6.2e-10 38.6 0.1 8.9 9 0 0 9 9 9 6 Tetratricopeptide repeat Pkinase_Tyr PF07714.17 KXS16950.1 - 8.8e-38 130.1 0.0 2.5e-23 82.7 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXS16950.1 - 1e-35 123.4 0.0 7.7e-35 120.5 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain TPR_8 PF13181.6 KXS16950.1 - 6.8e-19 66.4 3.3 0.017 15.3 0.0 7.3 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_7 PF13176.6 KXS16950.1 - 2.8e-14 52.0 18.1 0.052 13.6 0.0 8.4 9 0 0 9 9 8 5 Tetratricopeptide repeat TPR_2 PF07719.17 KXS16950.1 - 7.8e-13 47.5 17.3 0.01 15.9 0.0 8.2 9 0 0 9 9 8 4 Tetratricopeptide repeat Sel1 PF08238.12 KXS16950.1 - 8.6e-11 42.2 21.2 1.7e-08 34.9 2.6 5.9 8 0 0 8 8 4 3 Sel1 repeat TPR_17 PF13431.6 KXS16950.1 - 1.9e-10 40.3 14.3 0.032 14.6 0.1 6.4 7 0 0 7 7 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 KXS16950.1 - 4.9e-10 38.8 13.9 0.022 14.6 0.0 7.1 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_6 PF13174.6 KXS16950.1 - 7.3e-10 38.8 12.2 0.19 12.4 0.0 8.0 9 0 0 9 9 8 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KXS16950.1 - 1.9e-09 37.6 4.4 0.0021 18.2 0.0 5.7 2 1 4 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 KXS16950.1 - 5.3e-09 36.5 25.0 0.00089 19.7 0.1 7.3 5 2 2 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 KXS16950.1 - 5.4e-09 36.1 27.2 0.33 11.9 0.0 9.0 8 1 1 9 9 9 2 Tetratricopeptide repeat TPR_4 PF07721.14 KXS16950.1 - 9.6e-09 35.0 13.2 0.073 13.7 0.1 7.1 7 0 0 7 7 5 3 Tetratricopeptide repeat TPR_20 PF14561.6 KXS16950.1 - 3.2e-05 24.2 23.1 0.13 12.7 0.0 7.3 2 1 5 7 7 7 2 Tetratricopeptide repeat PPR PF01535.20 KXS16950.1 - 6.8e-05 22.8 3.6 23 5.5 0.0 6.5 8 0 0 8 8 6 0 PPR repeat TPR_16 PF13432.6 KXS16950.1 - 0.00036 21.1 29.7 0.14 12.9 0.4 6.2 5 2 0 6 6 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 KXS16950.1 - 0.024 14.3 10.0 13 5.6 0.0 6.2 6 0 0 6 6 6 0 TPR repeat PilO PF04350.13 KXS16950.1 - 0.088 13.0 0.0 8.8 6.5 0.0 2.8 1 1 1 2 2 2 0 Pilus assembly protein, PilO LRR_8 PF13855.6 KXS16951.1 - 1.8e-12 46.8 18.1 6e-07 29.1 1.5 3.5 3 1 1 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 KXS16951.1 - 1.3e-10 41.3 12.8 2.7e-05 24.4 0.2 4.0 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KXS16951.1 - 1.1e-05 25.1 2.2 0.11 12.0 0.1 3.7 2 1 2 4 4 4 3 Leucine-rich repeat LRR_6 PF13516.6 KXS16951.1 - 0.015 15.3 12.3 14 6.1 1.4 4.7 4 0 0 4 4 4 0 Leucine Rich repeat LRR_1 PF00560.33 KXS16951.1 - 0.17 12.5 6.3 23 6.1 0.4 4.1 3 1 1 4 4 4 0 Leucine Rich Repeat Y_phosphatase3 PF13350.6 KXS16954.1 - 1e-40 140.2 0.0 2.2e-40 139.1 0.0 1.5 2 0 0 2 2 2 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 KXS16954.1 - 0.024 14.2 0.0 0.11 12.0 0.0 1.8 2 0 0 2 2 2 0 Protein-tyrosine phosphatase Homeodomain PF00046.29 KXS16954.1 - 0.18 11.7 0.2 0.46 10.4 0.1 1.7 2 0 0 2 2 2 0 Homeodomain VASt PF16016.5 KXS16955.1 - 4.1e-09 37.0 0.0 5.4e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain PTS_2-RNA PF01885.16 KXS16956.1 - 2.5e-64 216.6 0.0 3e-64 216.4 0.0 1.0 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family RPE65 PF03055.15 KXS16956.1 - 0.16 11.1 0.0 0.22 10.7 0.0 1.1 1 0 0 1 1 1 0 Retinal pigment epithelial membrane protein Snf7 PF03357.21 KXS16958.1 - 2.2e-30 105.5 17.5 2.6e-30 105.3 17.5 1.1 1 0 0 1 1 1 1 Snf7 MAS20 PF02064.15 KXS16958.1 - 0.0039 17.3 5.5 0.098 12.8 5.0 2.1 1 1 1 2 2 2 2 MAS20 protein import receptor Fib_alpha PF08702.10 KXS16958.1 - 1.4 9.1 8.2 0.8 9.9 4.7 1.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF1043 PF06295.12 KXS16958.1 - 3.8 7.5 8.5 25 4.9 8.5 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1043) HSCB_C PF07743.13 KXS16958.1 - 4.3 7.9 13.3 0.88 10.1 4.4 2.6 2 1 0 2 2 2 0 HSCB C-terminal oligomerisation domain V-ATPase_H_N PF03224.14 KXS16959.1 - 0.011 15.1 0.1 0.011 15.1 0.1 1.1 1 0 0 1 1 1 0 V-ATPase subunit H FAM76 PF16046.5 KXS16960.1 - 0.0018 17.7 2.8 0.31 10.3 0.4 2.3 2 0 0 2 2 2 2 FAM76 protein BAR_3 PF16746.5 KXS16960.1 - 0.018 14.8 1.3 0.038 13.7 0.5 1.8 2 0 0 2 2 2 0 BAR domain of APPL family Fib_alpha PF08702.10 KXS16960.1 - 0.032 14.4 1.1 0.092 12.9 1.1 1.8 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family UPF0242 PF06785.11 KXS16960.1 - 0.11 12.6 6.5 0.17 11.9 6.5 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Bacillus_HBL PF05791.11 KXS16960.1 - 0.16 11.8 0.5 0.26 11.1 0.5 1.3 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) MPS2 PF17060.5 KXS16960.1 - 0.16 11.2 5.6 0.25 10.5 5.6 1.2 1 0 0 1 1 1 0 Monopolar spindle protein 2 Lebercilin PF15619.6 KXS16960.1 - 0.21 11.2 15.6 1.8 8.2 15.6 2.0 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease V_ATPase_I PF01496.19 KXS16960.1 - 0.35 8.7 2.0 0.46 8.3 2.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FapA PF03961.13 KXS16960.1 - 0.54 8.8 3.5 0.82 8.2 3.5 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF724 PF05266.14 KXS16960.1 - 0.88 9.4 7.9 0.69 9.7 6.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF724) PKcGMP_CC PF16808.5 KXS16960.1 - 2.5 8.0 11.0 0.76 9.7 0.2 3.0 2 1 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase SlyX PF04102.12 KXS16960.1 - 3.5 8.3 10.0 4.3 8.0 0.3 3.0 2 1 1 3 3 3 0 SlyX Spc7 PF08317.11 KXS16960.1 - 7.1 5.4 10.5 4.6 6.0 8.4 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF4200 PF13863.6 KXS16960.1 - 7.3 7.0 15.0 1.8 9.0 9.5 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) PAP1 PF08601.10 KXS16961.1 - 0.24 11.1 4.0 0.31 10.7 4.0 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 UreD PF01774.17 KXS16963.1 - 3.5e-47 161.1 0.0 4.2e-47 160.8 0.0 1.1 1 0 0 1 1 1 1 UreD urease accessory protein Herpes_U34 PF04541.13 KXS16964.1 - 0.036 13.3 0.0 0.04 13.2 0.0 1.0 1 0 0 1 1 1 0 Herpesvirus virion protein U34 SopA PF13981.6 KXS16964.1 - 0.1 13.0 0.1 0.12 12.9 0.1 1.1 1 0 0 1 1 1 0 SopA-like central domain Adaptin_N PF01602.20 KXS16965.1 - 3e-106 356.1 0.0 3.7e-106 355.8 0.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KXS16965.1 - 8.9e-14 51.9 0.3 4.4e-09 36.6 0.0 2.7 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KXS16965.1 - 4.1e-06 27.1 0.2 0.025 14.9 0.1 3.5 2 1 1 3 3 3 3 HEAT repeats HEAT PF02985.22 KXS16965.1 - 1.3e-05 25.0 2.0 2.2 8.7 0.0 4.4 4 0 0 4 4 4 3 HEAT repeat RTP1_C1 PF10363.9 KXS16965.1 - 0.0031 17.7 0.2 1.1 9.5 0.0 3.2 3 1 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 Nipped-B_C PF12830.7 KXS16965.1 - 0.03 14.3 0.1 4.7 7.1 0.0 3.1 3 0 0 3 3 3 0 Sister chromatid cohesion C-terminus Proteasom_PSMB PF10508.9 KXS16965.1 - 0.13 10.8 0.3 0.98 7.8 0.1 2.2 2 0 0 2 2 2 0 Proteasome non-ATPase 26S subunit Arf PF00025.21 KXS16966.1 - 3.6e-65 218.7 0.0 4.3e-65 218.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KXS16966.1 - 1.2e-14 54.6 0.0 1.6e-14 54.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KXS16966.1 - 9.7e-14 51.3 0.0 1.1e-13 51.1 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 KXS16966.1 - 1e-11 44.6 0.0 1.3e-11 44.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KXS16966.1 - 6.2e-11 42.1 1.8 1.7e-07 30.8 0.1 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 KXS16966.1 - 2e-10 40.5 0.0 2.3e-10 40.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KXS16966.1 - 0.0001 22.4 0.0 0.00017 21.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_18 PF13238.6 KXS16966.1 - 0.035 14.6 0.0 0.06 13.9 0.0 1.5 1 1 0 1 1 1 0 AAA domain 6PF2K PF01591.18 KXS16966.1 - 0.058 12.7 0.1 0.086 12.1 0.1 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase Potassium_chann PF11404.8 KXS16967.1 - 0.12 12.2 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 Potassium voltage-gated channel Tom37 PF10568.9 KXS16968.1 - 7.4e-26 90.9 0.0 1.5e-25 89.9 0.0 1.5 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_N_4 PF17172.4 KXS16968.1 - 1.3e-19 70.7 0.0 2.6e-19 69.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 KXS16968.1 - 2.8e-16 59.1 0.0 6.8e-16 57.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KXS16968.1 - 1.9e-05 24.6 0.0 4.1e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain TPX2 PF06886.11 KXS16968.1 - 7.4 6.9 8.6 6.6 7.1 6.3 2.0 2 0 0 2 2 2 0 Targeting protein for Xklp2 (TPX2) Lys_export PF03956.13 KXS16969.1 - 0.0076 15.8 3.2 0.012 15.2 1.2 2.2 1 1 1 2 2 2 1 Lysine exporter LysO ANAPC4_WD40 PF12894.7 KXS16970.1 - 0.0012 19.1 0.1 0.016 15.5 0.0 2.7 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain SARS_X4 PF08779.10 KXS16970.1 - 0.055 13.7 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 SARS coronavirus X4 like ETC_C1_NDUFA4 PF04800.12 KXS16970.1 - 0.18 12.1 0.0 0.44 10.8 0.0 1.6 1 0 0 1 1 1 0 ETC complex I subunit conserved region WD40 PF00400.32 KXS16970.1 - 0.34 11.8 6.8 4.8 8.2 0.1 3.5 3 0 0 3 3 3 0 WD domain, G-beta repeat Pkinase PF00069.25 KXS16971.1 - 1.1e-06 28.2 0.0 1.1e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS16971.1 - 0.023 14.0 0.0 0.026 13.8 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase UreF PF01730.16 KXS16974.1 - 4.8e-24 85.4 0.3 2.5e-22 79.9 0.0 2.7 1 1 1 2 2 2 1 UreF Abhydrolase_3 PF07859.13 KXS16975.1 - 2.1e-24 86.6 0.0 2.5e-24 86.3 0.0 1.0 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF378 PF04070.12 KXS16976.1 - 0.13 12.2 0.2 0.13 12.2 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF378) Rhomboid PF01694.22 KXS16976.1 - 0.48 10.4 7.6 1.2 9.2 7.6 1.7 1 0 0 1 1 1 0 Rhomboid family EGF_2 PF07974.13 KXS16976.1 - 2.7 8.4 9.0 4.4 7.8 9.0 1.3 1 0 0 1 1 1 0 EGF-like domain zf-MYND PF01753.18 KXS16977.1 - 1.6e-08 34.5 8.5 3e-08 33.6 8.5 1.4 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KXS16977.1 - 0.035 14.4 7.6 0.061 13.6 7.6 1.4 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Mito_fiss_reg PF05308.11 KXS16985.1 - 2.9 7.9 5.8 3 7.9 5.8 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator SepSecS PF05889.13 KXS16986.1 - 2.1e-105 352.6 0.0 3.3e-105 352.0 0.0 1.3 1 0 0 1 1 1 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS RRM_1 PF00076.22 KXS16986.1 - 1.6e-07 31.0 0.0 3.1e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) F-box-like PF12937.7 KXS16987.1 - 0.0002 21.2 0.1 0.00045 20.1 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box_5 PF18511.1 KXS16987.1 - 0.0077 15.8 0.2 0.021 14.4 0.0 1.8 2 0 0 2 2 2 1 F-box Mlh1_C PF16413.5 KXS16987.1 - 0.11 11.8 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 DNA mismatch repair protein Mlh1 C-terminus AA_permease_2 PF13520.6 KXS16989.1 - 1e-40 139.9 41.6 1.9e-29 102.8 26.0 2.0 1 1 1 2 2 2 2 Amino acid permease AA_permease PF00324.21 KXS16989.1 - 1.8e-12 46.6 35.3 7.3e-11 41.3 19.4 2.2 1 1 1 2 2 2 2 Amino acid permease Phage_holin_3_6 PF07332.11 KXS16989.1 - 0.22 11.6 0.0 0.22 11.6 0.0 4.8 4 1 0 4 4 4 0 Putative Actinobacterial Holin-X, holin superfamily III Ribosomal_S5_C PF03719.15 KXS16993.1 - 1.9e-24 84.9 0.1 3.7e-24 84.0 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 KXS16993.1 - 4.3e-21 74.7 4.9 8.5e-21 73.7 4.9 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain PCP_red PF08369.10 KXS16993.1 - 0.45 10.8 4.6 9.5 6.5 0.2 2.5 2 0 0 2 2 2 0 Proto-chlorophyllide reductase 57 kD subunit DUF3474 PF11960.8 KXS16996.1 - 3.3e-05 24.1 0.0 6.1e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) FA_desaturase PF00487.24 KXS16996.1 - 9e-05 22.4 44.7 0.0021 17.9 39.8 3.5 1 1 1 2 2 2 1 Fatty acid desaturase p450 PF00067.22 KXS16997.1 - 0.0057 15.5 2.2 0.87 8.3 0.0 2.1 1 1 1 2 2 2 2 Cytochrome P450 UPF0113_N PF17833.1 KXS16998.1 - 1.2e-29 102.6 0.0 1.7e-29 102.2 0.0 1.2 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 KXS16998.1 - 2.9e-12 46.7 0.0 1.3e-11 44.6 0.0 2.0 1 1 0 1 1 1 1 UPF0113 PUA domain ThiJ_like PF17124.5 KXS16999.1 - 1.2e-55 188.3 0.0 1.4e-55 188.1 0.0 1.1 1 0 0 1 1 1 1 ThiJ/PfpI family-like DJ-1_PfpI PF01965.24 KXS16999.1 - 8.7e-09 35.4 0.0 2.1e-08 34.1 0.0 1.9 1 1 0 1 1 1 1 DJ-1/PfpI family GATase_3 PF07685.14 KXS16999.1 - 0.015 14.9 0.0 0.022 14.4 0.0 1.2 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain SNO PF01174.19 KXS16999.1 - 0.026 14.4 0.0 0.046 13.6 0.0 1.3 1 0 0 1 1 1 0 SNO glutamine amidotransferase family Pyridoxal_deC PF00282.19 KXS17000.1 - 3.8e-69 233.2 0.0 5.1e-69 232.8 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 KXS17000.1 - 0.03 13.3 0.0 0.043 12.8 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V CDO_I PF05995.12 KXS17001.1 - 1.1e-35 122.4 0.0 1.7e-35 121.8 0.0 1.2 1 0 0 1 1 1 1 Cysteine dioxygenase type I PCO_ADO PF07847.12 KXS17001.1 - 3.9e-06 26.5 0.1 5.9e-06 25.9 0.1 1.2 1 0 0 1 1 1 1 PCO_ADO Cupin_7 PF12973.7 KXS17001.1 - 0.0089 15.9 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 ChrR Cupin-like domain PX PF00787.24 KXS17002.1 - 2.1e-07 30.9 1.1 6.7e-07 29.3 1.1 1.8 1 1 0 1 1 1 1 PX domain DUF5600 PF18150.1 KXS17003.1 - 2e-36 124.8 0.1 3.3e-36 124.1 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5600) Dynamin_N PF00350.23 KXS17003.1 - 3.1e-14 53.4 0.0 5.4e-13 49.3 0.0 2.1 1 1 0 1 1 1 1 Dynamin family EF-hand_4 PF12763.7 KXS17003.1 - 3.1e-13 49.6 0.0 7.1e-13 48.4 0.0 1.5 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EHD_N PF16880.5 KXS17003.1 - 1.8e-12 46.9 0.4 4.1e-12 45.8 0.4 1.7 1 0 0 1 1 1 1 N-terminal EH-domain containing protein MMR_HSR1 PF01926.23 KXS17003.1 - 9.5e-11 41.8 0.0 3.5e-10 40.0 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase EF-hand_8 PF13833.6 KXS17003.1 - 0.00092 19.0 0.1 0.86 9.5 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain pair Roc PF08477.13 KXS17003.1 - 0.001 19.3 0.0 1.1 9.5 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase EF-hand_1 PF00036.32 KXS17003.1 - 0.0011 18.4 0.2 0.0084 15.6 0.0 2.6 3 0 0 3 3 3 1 EF hand EF-hand_7 PF13499.6 KXS17003.1 - 0.0084 16.5 0.0 0.032 14.7 0.0 2.0 2 0 0 2 2 2 1 EF-hand domain pair Gtr1_RagA PF04670.12 KXS17003.1 - 0.014 14.7 0.0 0.048 13.0 0.0 1.7 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region DUF2267 PF10025.9 KXS17003.1 - 0.039 14.2 0.0 1.3 9.4 0.2 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2267) AIG1 PF04548.16 KXS17003.1 - 0.046 13.1 0.0 3.9 6.7 0.0 2.2 2 0 0 2 2 2 0 AIG1 family RsgA_GTPase PF03193.16 KXS17003.1 - 0.098 12.6 0.0 4.8 7.1 0.0 2.9 3 0 0 3 3 3 0 RsgA GTPase WD40 PF00400.32 KXS17004.1 - 1.6e-17 63.5 12.0 0.0011 19.7 0.1 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXS17004.1 - 6.4e-05 23.2 0.5 1.3 9.4 0.1 4.0 4 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KXS17004.1 - 0.0018 17.3 0.1 0.47 9.3 0.0 2.9 4 0 0 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein W_rich_C PF07483.11 KXS17004.1 - 0.057 13.6 2.1 0.18 12.0 0.3 2.5 3 0 0 3 3 3 0 Tryptophan-rich Synechocystis species C-terminal domain Mgm101p PF06420.12 KXS17005.1 - 1.1e-36 125.9 0.0 1.7e-36 125.3 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 Mito_carr PF00153.27 KXS17006.1 - 6.3e-64 211.9 7.5 5.8e-22 77.4 0.3 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Peptidase_S29 PF02907.15 KXS17006.1 - 0.011 15.5 0.3 0.018 14.8 0.3 1.4 1 0 0 1 1 1 0 Hepatitis C virus NS3 protease Serine_protease PF18405.1 KXS17006.1 - 1 8.5 3.4 16 4.5 0.1 3.1 2 2 0 3 3 3 0 Gammaproteobacterial serine protease HARE-HTH PF05066.13 KXS17007.1 - 0.06 13.7 0.0 0.17 12.3 0.0 1.7 1 0 0 1 1 1 0 HB1, ASXL, restriction endonuclease HTH domain zf-RING_5 PF14634.6 KXS17008.1 - 1.2e-08 34.8 4.1 2e-08 34.0 4.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KXS17008.1 - 8.5e-06 25.7 0.9 1.9e-05 24.6 0.9 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KXS17008.1 - 0.00047 20.0 4.6 0.00054 19.7 2.6 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KXS17008.1 - 0.0016 18.6 1.3 0.0053 16.9 0.1 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 KXS17008.1 - 0.0021 17.9 0.8 0.0021 17.9 0.8 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXS17008.1 - 0.0021 18.4 4.4 0.0048 17.2 4.4 1.7 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KXS17008.1 - 0.039 13.8 1.3 0.039 13.8 1.3 1.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Zn_Tnp_IS91 PF14319.6 KXS17008.1 - 0.047 13.7 0.7 0.12 12.4 0.7 1.6 1 0 0 1 1 1 0 Transposase zinc-binding domain DIT1_PvcA PF05141.12 KXS17008.1 - 0.08 12.4 0.3 0.12 11.8 0.3 1.1 1 0 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein Filament PF00038.21 KXS17008.1 - 0.15 11.6 5.0 0.35 10.4 4.4 1.6 1 1 1 2 2 2 0 Intermediate filament protein YlqD PF11068.8 KXS17008.1 - 0.22 11.9 0.6 0.34 11.3 0.6 1.2 1 0 0 1 1 1 0 YlqD protein zf-RING_11 PF17123.5 KXS17008.1 - 0.41 10.4 3.7 0.94 9.3 3.7 1.6 1 0 0 1 1 1 0 RING-like zinc finger Macoilin PF09726.9 KXS17008.1 - 6.1 5.3 7.9 0.56 8.7 0.2 2.0 2 0 0 2 2 2 0 Macoilin family Abhydrolase_3 PF07859.13 KXS17009.1 - 4.2e-23 82.3 0.3 1.4e-22 80.6 0.1 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KXS17009.1 - 2e-12 46.7 0.0 2.5e-12 46.3 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_1 PF00561.20 KXS17009.1 - 0.0023 17.6 0.0 0.0051 16.5 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold COesterase PF00135.28 KXS17009.1 - 0.033 13.1 0.0 1.1 8.1 0.0 2.1 2 0 0 2 2 2 0 Carboxylesterase family PAE PF03283.13 KXS17009.1 - 0.056 12.6 0.1 0.26 10.3 0.0 1.8 2 0 0 2 2 2 0 Pectinacetylesterase Peptidase_S9 PF00326.21 KXS17009.1 - 0.083 12.4 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 KXS17010.1 - 8e-22 78.1 0.0 1.8e-21 76.9 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KXS17010.1 - 2.1e-07 30.1 0.0 3.2e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_3 PF07859.13 KXS17011.1 - 4.1e-09 36.6 0.0 5.3e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Cyclin PF08613.11 KXS17013.1 - 3.7e-06 27.4 0.0 4e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Cyclin Lsm_interact PF05391.11 KXS17013.1 - 0.26 10.8 1.8 0.57 9.8 1.8 1.6 1 0 0 1 1 1 0 Lsm interaction motif zf-B_box PF00643.24 KXS17014.1 - 0.0016 18.6 8.4 0.0029 17.7 8.4 1.4 1 0 0 1 1 1 1 B-box zinc finger ZZ PF00569.17 KXS17014.1 - 0.17 11.8 8.4 0.32 10.8 8.4 1.4 1 0 0 1 1 1 0 Zinc finger, ZZ type Ank_5 PF13857.6 KXS17016.1 - 1.1e-24 86.2 2.6 2.6e-13 49.9 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXS17016.1 - 6.7e-21 74.4 4.6 1.4e-11 44.6 0.1 3.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXS17016.1 - 1.6e-18 67.0 0.0 5e-18 65.5 0.0 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXS17016.1 - 2.5e-17 61.2 0.1 1.6e-06 28.0 0.0 3.4 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 KXS17016.1 - 3.7e-15 55.6 0.9 3e-06 27.4 0.0 3.4 4 0 0 4 4 4 3 Ankyrin repeat HMG_box PF00505.19 KXS17017.1 - 2.1e-22 79.3 3.8 3.5e-16 59.4 2.3 2.4 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 KXS17017.1 - 9.7e-16 58.1 3.7 3e-13 50.1 1.0 2.4 2 0 0 2 2 2 2 HMG-box domain PB1 PF00564.24 KXS17019.1 - 1.5e-09 37.7 0.3 4.3e-09 36.2 0.0 1.9 2 0 0 2 2 2 1 PB1 domain HMG_box PF00505.19 KXS17021.1 - 2.7e-15 56.5 1.4 1.2e-08 35.3 1.0 2.3 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 KXS17021.1 - 1e-12 48.4 2.0 9.2e-05 23.0 1.7 2.6 2 1 0 2 2 2 2 HMG-box domain Fasciclin PF02469.22 KXS17022.1 - 9.5e-09 35.6 0.0 1.5e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 Fasciclin domain 2-Hacid_dh_C PF02826.19 KXS17026.1 - 2.7e-42 144.2 0.0 5.2e-30 104.1 0.0 2.1 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KXS17026.1 - 1e-10 41.4 0.0 9.9e-10 38.2 0.0 2.0 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KXS17026.1 - 0.14 12.4 0.0 0.27 11.4 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase WD40 PF00400.32 KXS17027.1 - 2.7e-07 31.2 15.7 0.026 15.4 0.1 6.5 6 0 0 6 6 6 4 WD domain, G-beta repeat ApbA PF02558.16 KXS17030.1 - 8.8e-24 83.9 0.0 1.5e-23 83.1 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 KXS17030.1 - 4.2e-21 75.4 0.3 1.9e-20 73.3 0.0 2.1 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA C terminal Pyr_redox_3 PF13738.6 KXS17030.1 - 0.088 12.0 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXS17030.1 - 0.17 12.2 1.0 0.33 11.2 1.0 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Aminotran_4 PF01063.19 KXS17031.1 - 1.5e-38 132.9 0.0 1.9e-38 132.5 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV HHH PF00633.23 KXS17031.1 - 0.14 12.1 0.3 1.2 9.2 0.1 2.5 2 0 0 2 2 2 0 Helix-hairpin-helix motif Rubella_Capsid PF05750.11 KXS17033.1 - 0.038 13.6 0.0 0.055 13.1 0.0 1.2 1 0 0 1 1 1 0 Rubella capsid protein Nitroreductase PF00881.24 KXS17034.1 - 2.8e-05 24.3 0.0 0.00089 19.3 0.0 2.6 3 0 0 3 3 3 1 Nitroreductase family Ank_2 PF12796.7 KXS17034.1 - 0.0042 17.6 0.1 0.1 13.2 0.0 2.6 1 1 2 3 3 3 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXS17034.1 - 0.097 13.0 0.1 1.9 8.9 0.0 3.0 2 1 1 3 3 3 0 Ankyrin repeats (many copies) F-box-like PF12937.7 KXS17035.1 - 0.18 11.7 0.3 0.42 10.6 0.3 1.6 1 0 0 1 1 1 0 F-box-like TPR_7 PF13176.6 KXS17036.1 - 0.056 13.5 0.2 4.4 7.6 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 KXS17036.1 - 0.51 11.3 2.5 1.2 10.1 0.2 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat SRF-TF PF00319.18 KXS17037.1 - 2.2e-23 81.5 0.1 3e-23 81.1 0.1 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) DUF3931 PF13082.6 KXS17037.1 - 0.16 12.2 0.0 1.3 9.3 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3931) DUF4953 PF16313.5 KXS17039.1 - 0.0035 16.6 0.0 0.0045 16.2 0.0 1.1 1 0 0 1 1 1 1 Met-zincin RRN3 PF05327.11 KXS17039.1 - 0.44 9.0 2.7 0.58 8.6 2.7 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 ABC_tran PF00005.27 KXS17043.1 - 8.5e-18 65.2 0.0 9.6e-18 65.0 0.0 1.0 1 0 0 1 1 1 1 ABC transporter LRR_4 PF12799.7 KXS17044.1 - 5.3e-05 23.5 1.2 0.013 15.9 0.3 4.1 5 0 0 5 5 5 1 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KXS17044.1 - 0.00093 19.1 9.3 12 6.2 0.2 6.9 8 0 0 8 8 8 2 Leucine Rich repeat F-box PF00646.33 KXS17044.1 - 0.051 13.5 1.1 0.15 12.0 1.1 1.8 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.7 KXS17044.1 - 0.057 13.3 1.5 0.2 11.6 1.5 2.0 1 0 0 1 1 1 0 F-box-like LRR_8 PF13855.6 KXS17044.1 - 0.42 10.4 4.6 1.1 9.1 0.4 3.5 4 0 0 4 4 4 0 Leucine rich repeat LRR_8 PF13855.6 KXS17045.1 - 0.00075 19.2 1.6 0.33 10.7 0.6 3.8 3 1 0 3 3 3 2 Leucine rich repeat LRR_6 PF13516.6 KXS17045.1 - 0.0015 18.4 1.1 13 6.1 0.0 5.7 6 0 0 6 6 6 1 Leucine Rich repeat LRR_4 PF12799.7 KXS17045.1 - 0.016 15.6 3.1 3.7 8.1 0.1 4.5 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) Herpes_capsid PF06112.11 KXS17047.1 - 9.3 6.3 23.0 0.21 11.6 16.3 1.7 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein WD40 PF00400.32 KXS17048.1 - 9.6e-39 130.7 12.1 8e-08 32.8 0.3 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXS17048.1 - 5.5e-09 36.2 1.8 0.23 11.8 0.4 5.3 1 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KXS17048.1 - 0.0072 15.0 1.3 0.31 9.7 0.1 3.0 2 1 1 3 3 3 1 Nucleoporin Nup120/160 Pirin PF02678.16 KXS17048.1 - 0.11 12.5 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Pirin Ge1_WD40 PF16529.5 KXS17048.1 - 0.12 11.4 3.9 0.46 9.4 0.6 3.1 2 2 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Phi_1 PF04674.12 KXS17049.1 - 1.9e-23 83.2 0.0 3.1e-23 82.4 0.0 1.2 1 0 0 1 1 1 1 Phosphate-induced protein 1 conserved region ERCC4 PF02732.15 KXS17053.1 - 7e-11 42.6 0.0 9.3e-11 42.2 0.0 1.1 1 0 0 1 1 1 1 ERCC4 domain KA1 PF02149.19 KXS17055.1 - 8.6e-20 70.3 0.1 1.3e-19 69.7 0.1 1.3 1 0 0 1 1 1 1 Kinase associated domain 1 Pkinase PF00069.25 KXS17056.1 - 5.8e-74 248.8 0.0 7.1e-74 248.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS17056.1 - 2.3e-45 154.9 0.0 2.9e-45 154.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXS17056.1 - 5.3e-06 26.0 0.0 1.9e-05 24.1 0.0 1.8 1 1 1 2 2 2 1 Kinase-like RIO1 PF01163.22 KXS17056.1 - 0.0004 20.1 0.8 0.00063 19.4 0.8 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 KXS17056.1 - 0.00085 18.7 0.4 0.0014 18.0 0.4 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KXS17056.1 - 0.0039 16.2 0.1 0.006 15.6 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain YukC PF10140.9 KXS17056.1 - 0.09 11.6 3.1 0.11 11.3 0.0 2.2 2 1 1 3 3 3 0 WXG100 protein secretion system (Wss), protein YukC APH PF01636.23 KXS17056.1 - 0.13 12.2 0.0 0.28 11.0 0.1 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family NUDIX PF00293.28 KXS17057.1 - 9.8e-16 58.0 0.1 1.2e-15 57.7 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 KXS17057.1 - 0.072 13.1 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 NUDIX domain Myb_DNA-bind_3 PF12776.7 KXS17060.1 - 0.023 15.7 1.4 1.2 10.2 0.0 3.0 2 2 1 3 3 3 0 Myb/SANT-like DNA-binding domain SEEEED PF14797.6 KXS17060.1 - 0.023 14.8 21.1 0.033 14.4 21.1 1.2 1 0 0 1 1 1 0 Serine-rich region of AP3B1, clathrin-adaptor complex CDC45 PF02724.14 KXS17060.1 - 0.15 10.4 7.8 0.17 10.1 7.8 1.1 1 0 0 1 1 1 0 CDC45-like protein FAD_binding_7 PF03441.14 KXS17061.1 - 9e-33 113.5 0.0 1.7e-32 112.6 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain of DNA photolyase Ank_2 PF12796.7 KXS17062.1 - 2e-05 25.1 0.0 0.015 15.8 0.0 3.3 3 1 1 4 4 4 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXS17062.1 - 0.00054 20.2 0.0 0.036 14.6 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 KXS17062.1 - 0.0078 16.6 0.0 0.24 11.9 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 KXS17062.1 - 0.008 16.7 0.0 0.82 10.3 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Kinesin_assoc PF16183.5 KXS17062.1 - 0.017 15.2 1.3 0.03 14.5 1.3 1.3 1 0 0 1 1 1 0 Kinesin-associated TPR_19 PF14559.6 KXS17064.1 - 4e-08 33.6 5.7 0.0018 18.8 2.2 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 KXS17064.1 - 9.4e-06 25.4 8.8 0.021 14.9 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KXS17064.1 - 1.3e-05 25.6 10.2 0.027 15.3 0.2 3.8 1 1 2 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KXS17064.1 - 2.2e-05 24.6 2.1 0.12 12.6 0.2 2.4 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 KXS17064.1 - 0.00017 22.2 18.8 0.00047 20.8 6.8 2.7 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 KXS17064.1 - 0.0045 17.1 6.0 0.12 12.6 1.2 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 KXS17064.1 - 0.0059 16.9 5.2 1.3 9.3 3.0 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KXS17064.1 - 0.0082 15.9 1.9 0.082 12.8 0.0 3.1 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 KXS17064.1 - 0.019 14.7 0.0 2.9 7.7 0.0 2.7 2 1 1 3 3 3 0 TPR repeat BTAD PF03704.17 KXS17064.1 - 0.036 14.5 1.8 0.036 14.5 1.8 2.5 2 1 1 3 3 3 0 Bacterial transcriptional activator domain DUF2019 PF09450.10 KXS17064.1 - 0.17 11.9 1.5 1.2 9.1 1.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF2019) TPR_8 PF13181.6 KXS17064.1 - 0.17 12.2 0.3 15 6.1 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 KXS17064.1 - 1.4 9.7 4.0 35 5.3 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF1771 PF08590.10 KXS17065.1 - 1.9e-14 53.8 6.7 3.4e-14 53.0 6.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.21 KXS17065.1 - 5.2e-05 23.5 0.1 0.00014 22.1 0.1 1.8 1 0 0 1 1 1 1 Smr domain CUE PF02845.16 KXS17065.1 - 0.00081 19.0 0.0 0.0016 18.1 0.0 1.4 1 0 0 1 1 1 1 CUE domain zf-CCCH PF00642.24 KXS17065.1 - 0.013 15.4 2.9 0.028 14.3 2.9 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 KXS17065.1 - 1.4 9.5 3.3 3 8.5 3.3 1.5 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger adh_short PF00106.25 KXS17066.1 - 1e-19 70.8 0.0 1.9e-19 69.9 0.0 1.4 1 1 1 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXS17066.1 - 4.3e-17 62.4 0.0 7.6e-17 61.6 0.0 1.4 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXS17066.1 - 1.7e-05 24.8 0.0 0.00043 20.2 0.0 2.3 2 0 0 2 2 2 1 KR domain Sacchrp_dh_NADP PF03435.18 KXS17066.1 - 0.018 15.3 0.0 0.034 14.4 0.0 1.6 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain DUF1776 PF08643.10 KXS17066.1 - 0.022 14.2 0.0 0.033 13.6 0.0 1.4 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) F420_oxidored PF03807.17 KXS17066.1 - 0.038 14.6 0.0 1.3 9.7 0.0 2.2 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 KXS17066.1 - 0.11 12.5 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Mucin PF01456.17 KXS17068.1 - 0.014 15.4 9.6 0.014 15.4 9.6 2.4 2 0 0 2 2 2 0 Mucin-like glycoprotein Mito_fiss_reg PF05308.11 KXS17068.1 - 0.19 11.8 3.5 0.13 12.3 0.2 2.1 2 0 0 2 2 2 0 Mitochondrial fission regulator PB1 PF00564.24 KXS17069.1 - 1.3e-09 37.8 0.1 3.8e-09 36.4 0.0 1.7 2 0 0 2 2 2 1 PB1 domain DSBA PF01323.20 KXS17070.1 - 4e-28 98.5 0.0 5.2e-28 98.1 0.0 1.2 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 KXS17070.1 - 0.018 15.2 0.0 0.028 14.6 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_3 PF13192.6 KXS17070.1 - 0.069 13.2 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin domain Aconitase PF00330.20 KXS17071.1 - 4.2e-152 507.4 0.0 5.3e-152 507.0 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KXS17071.1 - 6.8e-44 149.4 0.0 1.1e-43 148.7 0.0 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain MFS_1 PF07690.16 KXS17072.1 - 1e-22 80.5 0.4 1.2e-22 80.3 0.4 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 KXS17072.1 - 0.00025 19.5 0.4 0.0013 17.1 0.4 1.9 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.7 KXS17072.1 - 1.8 7.4 4.9 2.7 6.7 3.7 1.7 2 0 0 2 2 2 0 MFS_1 like family ECH_1 PF00378.20 KXS17073.1 - 1.2e-33 116.5 0.0 1.5e-33 116.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXS17073.1 - 1.6e-10 41.0 0.0 2e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase 2-Hacid_dh_C PF02826.19 KXS17074.1 - 1.6e-52 177.4 0.0 2.5e-52 176.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KXS17074.1 - 1.7e-18 66.5 0.0 2.4e-18 66.1 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KXS17074.1 - 0.00027 21.2 0.0 0.0012 19.0 0.0 2.0 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase FA_hydroxylase PF04116.13 KXS17075.1 - 7.3e-22 78.1 9.5 7.3e-22 78.1 9.5 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily FA_hydroxylase PF04116.13 KXS17076.1 - 4.2e-23 82.1 12.4 4.2e-23 82.1 12.4 1.7 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily MFS_1 PF07690.16 KXS17077.1 - 1.4e-47 162.4 55.6 1.2e-46 159.3 34.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXS17077.1 - 2.1e-09 36.8 10.0 2.1e-09 36.8 10.0 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter Retro_M PF02813.14 KXS17077.1 - 0.13 12.7 0.0 0.41 11.1 0.0 1.9 1 0 0 1 1 1 0 Retroviral M domain Mur_ligase_C PF02875.21 KXS17077.1 - 0.23 11.7 0.0 0.51 10.6 0.0 1.5 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain OATP PF03137.20 KXS17077.1 - 1.3 7.2 8.6 1.5 7.0 1.2 2.4 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Ldh_1_C PF02866.18 KXS17078.1 - 2e-48 164.5 0.0 3.8e-48 163.6 0.0 1.5 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 KXS17078.1 - 1.1e-45 155.2 0.1 1.5e-45 154.8 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KXS17078.1 - 0.14 11.1 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family MFS_1 PF07690.16 KXS17079.1 - 1.4e-21 76.9 33.0 1.4e-21 76.9 33.0 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Retrotran_gag_2 PF14223.6 KXS17080.1 - 0.036 13.7 0.0 0.95 9.1 0.0 2.3 1 1 1 2 2 2 0 gag-polypeptide of LTR copia-type Phage_P2_GpE PF06528.12 KXS17080.1 - 0.079 12.5 0.3 0.079 12.5 0.3 2.3 2 0 0 2 2 2 0 Phage P2 GpE Ribosomal_L23 PF00276.20 KXS17081.1 - 1.2e-15 57.6 0.0 2e-15 56.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L23 Sec23_trunk PF04811.15 KXS17082.1 - 2e-64 217.5 0.0 3e-64 216.9 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 KXS17082.1 - 2.3e-27 94.8 0.1 4.1e-27 94.0 0.1 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 KXS17082.1 - 1.3e-17 64.3 0.2 3.9e-17 62.8 0.0 1.9 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 KXS17082.1 - 1.7e-15 56.8 2.7 3.1e-15 55.9 2.7 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 KXS17082.1 - 5.7e-09 35.8 0.1 2.2e-08 33.9 0.0 2.0 2 0 0 2 2 2 1 Gelsolin repeat Vps36-NZF-N PF16988.5 KXS17082.1 - 0.019 14.4 0.1 0.042 13.2 0.1 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain VWA_2 PF13519.6 KXS17082.1 - 0.038 14.6 0.0 0.14 12.8 0.0 2.0 2 1 0 2 2 2 0 von Willebrand factor type A domain Bystin PF05291.11 KXS17083.1 - 4.1e-134 446.4 0.3 5.5e-134 446.0 0.3 1.1 1 0 0 1 1 1 1 Bystin F-box-like PF12937.7 KXS17084.1 - 0.083 12.8 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 F-box-like AP3D1 PF06375.11 KXS17084.1 - 0.23 11.7 0.3 0.38 11.0 0.3 1.2 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 Proteasom_PSMB PF10508.9 KXS17085.1 - 7.3e-26 90.7 0.0 7.7e-26 90.6 0.0 1.0 1 0 0 1 1 1 1 Proteasome non-ATPase 26S subunit DUF1981 PF09324.10 KXS17085.1 - 0.00028 20.7 0.0 0.15 11.9 0.0 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF1981) RPAP1_C PF08620.10 KXS17085.1 - 0.063 13.4 0.2 2.6 8.2 0.0 2.6 3 0 0 3 3 3 0 RPAP1-like, C-terminal Dynein_light PF01221.18 KXS17086.1 - 1e-40 137.9 0.7 1.1e-40 137.8 0.7 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Ectatomin PF06457.11 KXS17086.1 - 0.13 12.2 0.1 0.24 11.4 0.1 1.4 1 0 0 1 1 1 0 Ectatomin MRP-L46 PF11788.8 KXS17087.1 - 1.7e-13 51.3 0.0 2.8e-13 50.6 0.0 1.4 1 1 0 1 1 1 1 39S mitochondrial ribosomal protein L46 NUDIX PF00293.28 KXS17087.1 - 5.1e-11 42.7 0.1 9e-11 41.9 0.1 1.3 1 0 0 1 1 1 1 NUDIX domain PH PF00169.29 KXS17088.1 - 1.3e-05 25.7 0.0 2.4e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 PH domain FYVE PF01363.21 KXS17088.1 - 6.5e-05 23.0 13.2 0.00011 22.3 13.2 1.3 1 0 0 1 1 1 1 FYVE zinc finger PH_13 PF16652.5 KXS17088.1 - 0.012 15.4 0.2 1.4 8.7 0.3 2.4 2 1 0 2 2 2 0 Pleckstrin homology domain FYVE_2 PF02318.16 KXS17088.1 - 0.072 13.3 5.9 0.12 12.6 5.9 1.3 1 0 0 1 1 1 0 FYVE-type zinc finger SBP PF03110.14 KXS17088.1 - 6.8 7.1 10.7 29 5.1 10.8 2.0 1 1 1 2 2 2 0 SBP domain ANAPC3 PF12895.7 KXS17089.1 - 0.0014 18.9 1.1 0.0021 18.2 1.1 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 KXS17089.1 - 0.0014 19.2 2.8 0.02 15.6 1.6 2.1 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 KXS17089.1 - 0.0022 18.1 1.2 0.018 15.1 0.5 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 KXS17089.1 - 0.0035 17.3 5.0 0.07 13.3 0.9 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 KXS17089.1 - 0.0044 16.8 3.5 0.43 10.5 0.5 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 KXS17089.1 - 0.025 14.8 0.9 1.8 9.0 0.3 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 KXS17089.1 - 0.033 14.7 0.7 0.16 12.5 0.6 1.9 1 1 1 2 2 2 0 Tetratricopeptide repeat BCAS2 PF05700.11 KXS17090.1 - 5.5e-62 209.1 5.6 6.6e-62 208.9 5.6 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) Enkurin PF13864.6 KXS17090.1 - 0.57 10.7 4.1 0.2 12.1 0.6 2.1 2 1 0 2 2 2 0 Calmodulin-binding Snf7 PF03357.21 KXS17090.1 - 4.4 6.9 7.5 0.44 10.1 0.1 2.6 3 1 1 4 4 4 0 Snf7 Ribosomal_L33 PF00471.20 KXS17091.1 - 8.4e-08 32.5 0.0 1e-07 32.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L33 ER PF01133.17 KXS17092.1 - 5.5e-36 122.5 0.5 6.2e-36 122.3 0.5 1.0 1 0 0 1 1 1 1 Enhancer of rudimentary TelA PF05816.11 KXS17092.1 - 0.0026 16.9 0.2 0.0029 16.7 0.2 1.0 1 0 0 1 1 1 1 Toxic anion resistance protein (TelA) GPW_gp25 PF04965.14 KXS17092.1 - 0.077 12.8 0.1 0.21 11.4 0.0 1.6 2 0 0 2 2 2 0 Gene 25-like lysozyme UQ_con PF00179.26 KXS17093.1 - 2.8e-44 150.2 0.1 1.9e-27 95.6 0.0 2.7 3 0 0 3 3 3 2 Ubiquitin-conjugating enzyme UEV PF05743.13 KXS17093.1 - 0.0001 22.1 0.0 0.00021 21.2 0.0 1.4 1 0 0 1 1 1 1 UEV domain RWD PF05773.22 KXS17093.1 - 0.11 12.8 0.3 0.75 10.1 0.0 2.4 2 1 0 2 2 2 0 RWD domain NUC153 PF08159.12 KXS17094.1 - 1.2e-12 47.4 8.4 2.3e-11 43.3 0.8 3.9 3 1 0 3 3 3 2 NUC153 domain DUF1769 PF08588.10 KXS17095.1 - 2.2e-15 56.6 2.6 2.9e-15 56.2 1.4 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1769) Glyco_transf_20 PF00982.21 KXS17097.1 - 3.6e-148 494.2 0.0 4.8e-148 493.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 KXS17097.1 - 2e-73 246.4 0.0 3e-73 245.8 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.12 KXS17097.1 - 3.2e-06 27.1 0.0 0.011 15.5 0.0 2.3 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Snf7 PF03357.21 KXS17098.1 - 4.7e-49 166.3 14.8 5.5e-49 166.1 14.8 1.0 1 0 0 1 1 1 1 Snf7 DUF1319 PF07028.11 KXS17098.1 - 0.17 12.1 2.6 0.26 11.5 0.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1319) Bcr-Abl_Oligo PF09036.10 KXS17098.1 - 0.17 11.9 4.0 4.5 7.3 0.2 3.1 2 1 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain DUF4337 PF14235.6 KXS17098.1 - 0.47 10.5 10.9 4.1 7.5 5.8 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) NPV_P10 PF05531.12 KXS17098.1 - 0.83 10.2 4.1 17 5.9 1.3 2.7 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Prefoldin_2 PF01920.20 KXS17098.1 - 0.93 9.5 15.4 0.59 10.1 0.2 3.7 1 1 3 5 5 5 0 Prefoldin subunit FapA PF03961.13 KXS17098.1 - 1.4 7.4 11.8 2.7 6.5 6.8 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A Prefoldin PF02996.17 KXS17098.1 - 1.5 8.7 13.8 5.1 7.0 0.1 3.7 3 1 2 5 5 5 0 Prefoldin subunit EMP70 PF02990.16 KXS17099.1 - 8.1e-200 664.9 4.8 1.2e-199 664.3 4.8 1.3 1 0 0 1 1 1 1 Endomembrane protein 70 Acetyltransf_1 PF00583.25 KXS17100.1 - 3.7e-13 49.7 0.1 5e-13 49.3 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXS17100.1 - 2.8e-07 30.9 0.0 4.3e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KXS17100.1 - 9.2e-06 25.6 0.1 1.2e-05 25.2 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain TSC22 PF01166.18 KXS17101.1 - 0.023 15.0 2.7 0.047 14.0 2.7 1.6 1 0 0 1 1 1 0 TSC-22/dip/bun family SlyX PF04102.12 KXS17101.1 - 0.05 14.2 5.6 0.37 11.5 6.1 1.9 2 0 0 2 2 2 0 SlyX Roughex PF06020.11 KXS17101.1 - 0.13 11.3 2.5 0.15 11.1 2.5 1.1 1 0 0 1 1 1 0 Drosophila roughex protein DivIC PF04977.15 KXS17101.1 - 1 9.1 4.8 1.8 8.4 4.8 1.4 1 0 0 1 1 1 0 Septum formation initiator NTF2 PF02136.20 KXS17102.1 - 8.6e-30 103.8 0.5 1.6e-29 102.9 0.5 1.4 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.22 KXS17102.1 - 1.4e-12 47.2 0.0 2.6e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4518 PF15008.6 KXS17102.1 - 0.0001 21.6 0.4 0.00016 20.9 0.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4518) RRM_3 PF08777.11 KXS17102.1 - 0.0035 17.4 0.0 0.0067 16.5 0.0 1.4 1 0 0 1 1 1 1 RNA binding motif RRM_occluded PF16842.5 KXS17102.1 - 0.055 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 KXS17102.1 - 0.12 12.4 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif SRP40_C PF05022.12 KXS17103.1 - 3.6e-27 95.0 3.9 3.6e-27 95.0 3.9 2.3 2 0 0 2 2 2 1 SRP40, C-terminal domain DUF4692 PF15763.5 KXS17103.1 - 0.0061 17.0 5.2 0.0061 17.0 5.2 5.9 1 1 5 6 6 6 1 Regulator of human erythroid cell expansion (RHEX) LisH PF08513.11 KXS17103.1 - 0.0061 16.5 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 LisH Glyco_transf_90 PF05686.12 KXS17105.1 - 0.041 12.8 0.0 0.045 12.7 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 90 DUF4203 PF13886.6 KXS17106.1 - 3.3e-05 23.7 17.0 3.3e-05 23.7 17.0 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4203) ATP-synt_S1 PF05827.12 KXS17106.1 - 2.4 8.0 4.3 0.98 9.2 0.5 2.0 1 1 1 2 2 2 0 Vacuolar ATP synthase subunit S1 (ATP6S1) DUF2929 PF11151.8 KXS17106.1 - 4.4 7.7 13.4 4.1 7.8 5.2 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF2929) DUF1972 PF09314.11 KXS17107.1 - 0.054 13.1 0.0 0.075 12.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1972) BTB PF00651.31 KXS17108.1 - 9.1e-05 22.7 0.1 0.00028 21.1 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain Sgf11 PF08209.11 KXS17108.1 - 0.011 15.2 2.0 0.048 13.2 2.0 2.0 1 1 0 1 1 1 0 Sgf11 (transcriptional regulation protein) Proteasome PF00227.26 KXS17109.1 - 1.5e-48 164.8 0.9 1.8e-48 164.5 0.1 1.5 2 0 0 2 2 2 1 Proteasome subunit Proteasome_A_N PF10584.9 KXS17109.1 - 4.3e-13 48.7 0.2 7e-13 48.0 0.2 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature PAS_9 PF13426.7 KXS17110.1 - 1.4e-27 96.0 0.0 3.3e-16 59.4 0.0 3.6 3 1 0 3 3 3 3 PAS domain PAS PF00989.25 KXS17110.1 - 7.5e-17 61.4 0.0 7.1e-10 38.9 0.0 3.7 3 1 0 3 3 3 3 PAS fold PAS_3 PF08447.12 KXS17110.1 - 5.2e-14 52.3 0.0 1e-07 32.1 0.0 3.6 3 0 0 3 3 3 3 PAS fold PAS_4 PF08448.10 KXS17110.1 - 2.1e-12 47.3 0.0 0.0002 21.6 0.0 4.3 4 1 0 4 4 4 3 PAS fold PAS_11 PF14598.6 KXS17110.1 - 1.4e-07 31.6 0.0 3.6e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 PAS domain PAS_8 PF13188.7 KXS17110.1 - 6.4e-06 26.1 0.0 0.0045 17.0 0.0 2.7 2 0 0 2 2 2 2 PAS domain DUF5578 PF17741.1 KXS17112.1 - 6.1e-91 304.6 3.1 1.4e-90 303.4 0.3 2.0 2 0 0 2 2 2 1 Family of unknown function (DUF5578) Drf_GBD PF06371.13 KXS17112.1 - 0.015 14.9 0.2 0.063 12.8 0.0 2.1 2 0 0 2 2 2 0 Diaphanous GTPase-binding Domain HbrB PF08539.11 KXS17113.1 - 0.075 13.0 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 HbrB-like Tropomyosin_1 PF12718.7 KXS17114.1 - 1.5 9.0 6.9 0.72 10.0 0.2 2.8 2 1 1 3 3 3 0 Tropomyosin like Acetyltransf_3 PF13302.7 KXS17115.1 - 4.6e-34 118.1 0.0 5.9e-34 117.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXS17115.1 - 0.00012 22.3 0.0 0.00057 20.1 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family FAD-oxidase_C PF02913.19 KXS17116.1 - 1.2e-54 185.6 0.0 1.8e-54 185.0 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KXS17116.1 - 2.4e-41 140.7 0.5 5.2e-41 139.6 0.2 1.7 2 0 0 2 2 2 1 FAD binding domain Peripla_BP_4 PF13407.6 KXS17116.1 - 0.1 12.1 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Periplasmic binding protein domain AP_endonuc_2 PF01261.24 KXS17116.1 - 0.15 11.5 0.0 0.38 10.2 0.0 1.6 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel ANF_receptor PF01094.28 KXS17116.1 - 0.15 11.1 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 Receptor family ligand binding region DEAD_2 PF06733.15 KXS17118.1 - 4.5e-41 140.4 0.0 8.9e-41 139.4 0.0 1.4 1 0 0 1 1 1 1 DEAD_2 TPR_2 PF07719.17 KXS17119.1 - 6.8e-25 85.1 15.0 0.018 15.1 0.2 8.6 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_1 PF00515.28 KXS17119.1 - 2.4e-22 77.8 6.7 0.0097 15.7 0.0 7.9 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_8 PF13181.6 KXS17119.1 - 6.3e-22 75.9 1.9 0.016 15.4 0.0 8.2 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_19 PF14559.6 KXS17119.1 - 2.7e-15 56.6 0.9 0.074 13.6 0.1 7.7 5 1 4 9 9 9 4 Tetratricopeptide repeat ANAPC3 PF12895.7 KXS17119.1 - 1.7e-14 53.8 6.4 1.8e-07 31.3 0.0 5.0 3 1 2 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 KXS17119.1 - 5.4e-12 45.2 4.8 0.0045 16.6 0.0 6.1 4 2 2 6 6 6 3 TPR repeat TPR_14 PF13428.6 KXS17119.1 - 1e-11 44.6 13.7 0.019 15.8 0.5 8.5 4 1 5 9 9 9 2 Tetratricopeptide repeat TPR_16 PF13432.6 KXS17119.1 - 2.8e-11 43.9 7.0 0.0017 19.0 1.1 6.0 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 KXS17119.1 - 2.9e-09 36.7 0.4 1 9.9 0.1 7.5 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_12 PF13424.6 KXS17119.1 - 5.6e-09 36.2 14.2 1.1 9.6 0.9 7.5 5 3 2 7 7 7 4 Tetratricopeptide repeat TPR_9 PF13371.6 KXS17119.1 - 1e-06 28.8 6.0 3.3 7.9 0.1 6.1 5 1 2 7 7 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 KXS17119.1 - 4.2e-06 26.4 9.7 0.1 12.7 0.1 6.4 7 0 0 7 7 7 2 Tetratricopeptide repeat Helicase_C_2 PF13307.6 KXS17119.1 - 0.00011 22.4 0.0 0.00031 20.9 0.0 1.7 1 0 0 1 1 1 1 Helicase C-terminal domain TPR_6 PF13174.6 KXS17119.1 - 0.00082 19.9 8.4 20 6.1 0.0 7.0 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_10 PF13374.6 KXS17119.1 - 0.0094 15.8 8.8 1.9 8.5 0.1 5.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_21 PF09976.9 KXS17119.1 - 0.041 13.6 2.1 0.55 9.9 0.0 3.2 3 1 1 4 4 4 0 Tetratricopeptide repeat-like domain SRP_TPR_like PF17004.5 KXS17119.1 - 0.056 13.5 0.0 11 6.1 0.0 2.6 2 0 0 2 2 2 0 Putative TPR-like repeat MWFE PF15879.5 KXS17120.1 - 2.6e-14 53.1 2.6 3.3e-14 52.8 2.6 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase MWFE subunit Glyco_hydro_114 PF03537.13 KXS17122.1 - 1.9e-60 204.0 0.0 2.1e-60 203.9 0.0 1.0 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 SH3_1 PF00018.28 KXS17123.1 - 2.1e-08 33.6 0.1 1.3e-07 31.1 0.0 2.2 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 KXS17123.1 - 1.4e-06 28.0 0.2 8e-06 25.6 0.1 2.3 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 KXS17123.1 - 0.00017 21.2 0.2 0.00088 18.9 0.2 2.1 1 1 0 1 1 1 1 Variant SH3 domain SMC_hinge PF06470.13 KXS17124.1 - 7.6e-06 26.2 1.3 2.9e-05 24.4 0.0 2.6 3 1 0 3 3 3 1 SMC proteins Flexible Hinge Domain HMMR_N PF15905.5 KXS17124.1 - 0.0021 17.6 3.4 0.0021 17.6 3.4 3.6 2 1 2 4 4 4 1 Hyaluronan mediated motility receptor N-terminal APG6_N PF17675.1 KXS17124.1 - 0.0033 18.0 5.1 0.0033 18.0 5.1 5.1 2 1 2 5 5 5 1 Apg6 coiled-coil region Taxilin PF09728.9 KXS17124.1 - 0.0074 15.5 52.0 0.11 11.6 35.1 2.8 1 1 1 2 2 2 2 Myosin-like coiled-coil protein DUF4618 PF15397.6 KXS17124.1 - 0.012 15.0 4.4 0.012 15.0 4.4 3.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4618) BRE1 PF08647.11 KXS17124.1 - 0.022 14.8 2.6 0.022 14.8 2.6 6.3 3 2 3 6 6 6 0 BRE1 E3 ubiquitin ligase FlaC_arch PF05377.11 KXS17124.1 - 0.024 15.0 0.1 0.024 15.0 0.1 7.1 4 3 3 7 7 7 0 Flagella accessory protein C (FlaC) HemX PF04375.14 KXS17124.1 - 0.1 11.9 0.1 0.1 11.9 0.1 4.8 2 1 3 5 5 5 0 HemX, putative uroporphyrinogen-III C-methyltransferase ATG16 PF08614.11 KXS17124.1 - 0.73 10.0 55.0 0.075 13.3 17.5 4.1 1 1 3 4 4 4 0 Autophagy protein 16 (ATG16) MAD PF05557.13 KXS17124.1 - 4.1 5.6 54.6 0.18 10.1 9.4 2.9 1 1 2 3 3 3 0 Mitotic checkpoint protein Exonuc_VII_L PF02601.15 KXS17125.1 - 0.0022 17.6 7.3 0.0027 17.3 7.3 1.0 1 0 0 1 1 1 1 Exonuclease VII, large subunit EzrA PF06160.12 KXS17125.1 - 0.0063 14.8 16.4 0.0085 14.3 16.4 1.2 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA MPS2 PF17060.5 KXS17125.1 - 0.036 13.3 8.2 0.042 13.1 8.2 1.1 1 0 0 1 1 1 0 Monopolar spindle protein 2 Sec20 PF03908.13 KXS17125.1 - 0.086 12.8 2.9 1.2 9.1 1.0 2.4 2 0 0 2 2 2 0 Sec20 Fer4_22 PF17179.4 KXS17125.1 - 0.22 12.4 0.3 0.22 12.4 0.3 2.1 1 1 1 2 2 2 0 4Fe-4S dicluster domain KASH_CCD PF14662.6 KXS17125.1 - 0.28 11.0 25.5 0.66 9.8 17.5 2.4 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH ATG16 PF08614.11 KXS17125.1 - 0.43 10.8 23.8 0.74 10.0 23.8 1.4 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Spc29 PF17082.5 KXS17125.1 - 0.44 10.3 7.1 0.38 10.6 6.0 1.6 1 1 0 1 1 1 0 Spindle Pole Component 29 Nmad5 PF18757.1 KXS17125.1 - 0.69 10.1 14.1 1 9.6 14.1 1.3 1 0 0 1 1 1 0 Nucleotide modification associated domain 5 FUSC PF04632.12 KXS17125.1 - 0.82 8.1 1.3 0.93 7.9 1.3 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family MAD PF05557.13 KXS17125.1 - 1.9 6.8 26.0 5.1 5.3 26.1 1.5 1 1 0 1 1 1 0 Mitotic checkpoint protein DUF3584 PF12128.8 KXS17125.1 - 1.9 5.9 19.9 3.5 5.0 19.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) BRE1 PF08647.11 KXS17125.1 - 2.3 8.3 24.6 25 5.1 22.4 2.8 1 1 0 1 1 1 0 BRE1 E3 ubiquitin ligase Fib_alpha PF08702.10 KXS17125.1 - 2.4 8.3 12.0 0.79 9.9 7.5 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family CREPT PF16566.5 KXS17125.1 - 2.9 8.0 16.1 3.5 7.8 1.8 2.3 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour DUF948 PF06103.11 KXS17125.1 - 3.8 7.8 5.2 6.6 7.1 2.2 2.8 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) FAM167 PF11652.8 KXS17125.1 - 3.8 8.1 6.5 2.1 8.9 2.9 2.2 1 1 1 2 2 2 0 FAM167 Laminin_II PF06009.12 KXS17125.1 - 4.5 7.3 12.3 2.1 8.4 9.2 2.0 2 1 0 2 2 2 0 Laminin Domain II DHR10 PF18595.1 KXS17125.1 - 5.2 7.1 29.3 4.7 7.3 4.0 2.9 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain ApoO PF09769.9 KXS17125.1 - 6.1 6.8 6.3 1.5e+02 2.3 6.3 2.5 1 1 0 1 1 1 0 Apolipoprotein O COG2 PF06148.11 KXS17125.1 - 6.2 6.9 12.1 0.58 10.2 5.8 2.3 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 V_ATPase_I PF01496.19 KXS17125.1 - 6.8 4.5 13.0 8.1 4.2 13.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3450 PF11932.8 KXS17125.1 - 7.3 5.8 19.3 1.7 7.9 2.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) APG6_N PF17675.1 KXS17125.1 - 7.8 7.0 33.0 2 8.9 16.6 2.5 1 1 1 2 2 2 0 Apg6 coiled-coil region Ank_3 PF13606.6 KXS17127.1 - 5.7e-06 26.3 0.0 0.0012 19.1 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.7 KXS17127.1 - 6.2e-05 23.5 0.0 0.00012 22.6 0.0 1.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXS17127.1 - 0.0001 22.8 0.0 0.00015 22.3 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 KXS17127.1 - 0.00059 20.2 0.0 0.33 11.5 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 KXS17127.1 - 0.15 12.4 0.1 2.4 8.6 0.0 2.0 1 1 1 2 2 2 0 Ankyrin repeats (many copies) CUE PF02845.16 KXS17127.1 - 0.18 11.6 0.1 3.4 7.5 0.0 2.4 3 0 0 3 3 3 0 CUE domain DEAD PF00270.29 KXS17128.1 - 4.1e-46 156.9 0.0 7.2e-46 156.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXS17128.1 - 3.4e-27 95.0 0.0 1.6e-25 89.6 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXS17128.1 - 0.0012 18.9 0.0 0.0023 17.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF4644 PF15486.6 KXS17128.1 - 0.034 13.9 0.5 0.057 13.2 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4644) TraB PF01963.17 KXS17129.1 - 0.0045 16.9 0.0 0.012 15.5 0.0 1.7 2 0 0 2 2 2 1 TraB family Arginase PF00491.21 KXS17132.1 - 1.4e-71 241.2 0.0 1.7e-71 241.0 0.0 1.0 1 0 0 1 1 1 1 Arginase family Methyltransf_12 PF08242.12 KXS17133.1 - 2.7e-06 28.0 0.0 6.1e-06 26.9 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXS17133.1 - 8.2e-06 26.4 0.1 5.9e-05 23.6 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXS17133.1 - 1.8e-05 25.3 0.0 0.00013 22.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXS17133.1 - 0.00013 21.8 0.0 0.00019 21.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KXS17133.1 - 0.0046 16.3 0.0 0.031 13.6 0.0 1.9 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase PCMT PF01135.19 KXS17133.1 - 0.016 14.9 0.0 0.024 14.4 0.0 1.1 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 KXS17133.1 - 0.11 12.2 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Mob1_phocein PF03637.17 KXS17134.1 - 3.2e-83 277.9 0.0 3.8e-83 277.6 0.0 1.1 1 0 0 1 1 1 1 Mob1/phocein family CRAL_TRIO PF00650.20 KXS17135.1 - 3.5e-08 33.3 0.0 5.9e-08 32.6 0.0 1.4 1 1 0 1 1 1 1 CRAL/TRIO domain Rhomboid PF01694.22 KXS17137.1 - 7.1e-25 87.8 13.7 7.1e-25 87.8 13.7 1.4 2 0 0 2 2 2 1 Rhomboid family Autophagy_N PF03986.13 KXS17138.1 - 7.6e-40 136.0 0.1 1.3e-39 135.2 0.1 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.15 KXS17138.1 - 9.4e-14 51.8 0.3 3.1e-13 50.1 0.1 1.9 2 0 0 2 2 2 1 Autophagocytosis associated protein, active-site domain Autophagy_C PF10381.9 KXS17138.1 - 6.4e-12 44.8 1.5 1.2e-11 43.9 1.5 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal Asparaginase PF00710.20 KXS17138.1 - 0.063 12.8 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Asparaginase, N-terminal Cation_ATPase_C PF00689.21 KXS17139.1 - 3.8e-46 157.1 9.0 3.8e-46 157.1 9.0 2.0 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KXS17139.1 - 5.8e-38 130.2 2.3 5.8e-38 130.2 2.3 2.9 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 KXS17139.1 - 1.4e-18 67.9 0.8 4.7e-18 66.3 0.8 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KXS17139.1 - 1.7e-16 60.0 0.0 3.4e-16 59.1 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KXS17139.1 - 6.2e-12 45.0 0.8 1.8e-09 37.1 0.8 2.6 1 1 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KXS17139.1 - 8.9e-06 25.6 0.2 0.00051 19.9 0.3 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF5316 PF17247.2 KXS17139.1 - 0.091 12.8 0.1 2.8 8.0 0.0 3.3 3 0 0 3 3 3 0 Family of unknown function (DUF5316) DUF3533 PF12051.8 KXS17140.1 - 1.8e-06 27.1 9.9 3.3e-06 26.3 9.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) Pex24p PF06398.11 KXS17140.1 - 1.8 7.5 8.9 0.85 8.5 6.0 1.9 1 1 0 1 1 1 0 Integral peroxisomal membrane peroxin Abhydrolase_3 PF07859.13 KXS17141.1 - 2.4e-11 43.9 1.1 9.8e-11 41.9 1.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KXS17141.1 - 2.1e-07 30.2 0.0 1.3e-06 27.6 0.0 1.9 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.7 KXS17141.1 - 0.0088 16.7 1.0 0.012 16.2 1.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KXS17141.1 - 0.013 15.0 0.2 0.03 13.8 0.2 1.6 1 1 0 1 1 1 0 Prolyl oligopeptidase family Esterase_phd PF10503.9 KXS17141.1 - 0.052 13.0 0.0 0.2 11.1 0.0 1.8 1 1 0 1 1 1 0 Esterase PHB depolymerase TPR_7 PF13176.6 KXS17142.1 - 0.00059 19.7 0.0 0.33 11.1 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat HOASN PF14515.6 KXS17143.1 - 0.17 12.3 0.0 0.28 11.6 0.0 1.4 1 0 0 1 1 1 0 Haem-oxygenase-associated N-terminal helices Orthopox_A5L PF06193.11 KXS17147.1 - 0.057 12.9 1.0 0.072 12.5 1.0 1.1 1 0 0 1 1 1 0 Orthopoxvirus A5L protein-like adh_short_C2 PF13561.6 KXS17149.1 - 5.6e-47 160.3 0.0 6.2e-47 160.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXS17149.1 - 1.9e-31 109.1 0.0 2.6e-31 108.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase ZZ PF00569.17 KXS17150.1 - 1.8e-39 133.3 74.7 2.5e-09 36.8 9.1 6.5 6 1 0 6 6 6 5 Zinc finger, ZZ type C1_2 PF03107.16 KXS17150.1 - 1.3e-15 57.5 57.8 7.7e-05 22.9 0.9 7.0 7 0 0 7 7 7 6 C1 domain adh_short_C2 PF13561.6 KXS17151.1 - 3.9e-05 23.3 0.0 4.8e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ZZ PF00569.17 KXS17152.1 - 2.2e-43 145.8 66.1 5.9e-11 42.0 6.0 5.6 6 0 0 6 6 6 5 Zinc finger, ZZ type C1_2 PF03107.16 KXS17152.1 - 2.2e-14 53.5 54.7 0.00059 20.1 3.5 6.7 6 1 0 6 6 6 5 C1 domain Ank_2 PF12796.7 KXS17153.1 - 6.6e-19 68.3 3.2 1.5e-10 41.5 0.9 2.5 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXS17153.1 - 1.3e-11 44.5 9.6 0.0038 17.5 0.1 5.3 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 KXS17153.1 - 7.9e-10 38.7 11.3 0.062 13.8 0.2 5.2 5 1 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 KXS17153.1 - 6.1e-09 35.4 2.7 0.8 10.5 0.0 5.6 5 1 1 6 6 6 3 Ankyrin repeat Ank_4 PF13637.6 KXS17153.1 - 8.6e-09 35.8 4.7 0.052 14.1 0.2 4.6 2 2 3 6 6 6 5 Ankyrin repeats (many copies) B12-binding PF02310.19 KXS17153.1 - 0.0035 17.4 0.3 0.0066 16.5 0.3 1.4 1 0 0 1 1 1 1 B12 binding domain Aminotran_1_2 PF00155.21 KXS17155.1 - 6.6e-27 94.6 0.0 9.8e-27 94.1 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 KXS17155.1 - 0.0057 15.5 0.0 0.01 14.6 0.0 1.3 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase ABC_tran PF00005.27 KXS17156.1 - 1.1e-42 145.8 1.4 8.7e-22 78.1 0.0 4.0 4 1 0 4 4 2 2 ABC transporter AAA_21 PF13304.6 KXS17156.1 - 7.7e-16 58.8 0.0 0.021 14.6 0.1 4.3 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran_Xtn PF12848.7 KXS17156.1 - 1.7e-10 40.7 3.5 1.7e-10 40.7 3.5 3.1 3 0 0 3 3 3 1 ABC transporter SMC_N PF02463.19 KXS17156.1 - 4.7e-08 32.7 0.2 0.15 11.5 0.0 4.2 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KXS17156.1 - 3.3e-07 30.4 2.2 0.0044 17.1 0.0 3.4 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_29 PF13555.6 KXS17156.1 - 3.4e-06 26.7 0.5 0.05 13.3 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KXS17156.1 - 8.5e-06 25.8 0.4 0.17 11.8 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 KXS17156.1 - 2.3e-05 25.0 3.7 0.071 13.6 0.1 3.5 3 0 0 3 3 3 2 AAA domain AAA_18 PF13238.6 KXS17156.1 - 0.00087 19.8 0.5 1.5 9.3 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 KXS17156.1 - 0.0029 17.9 2.6 4.9 7.4 0.0 4.1 3 1 1 4 4 4 1 AAA domain RNA_helicase PF00910.22 KXS17156.1 - 0.0098 16.3 0.1 2.5 8.5 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA PF00004.29 KXS17156.1 - 0.01 16.3 0.0 2.3 8.6 0.0 3.0 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KXS17156.1 - 0.013 15.6 5.4 1.3 9.2 0.0 3.7 3 1 0 3 3 3 0 AAA domain AAA_24 PF13479.6 KXS17156.1 - 0.018 14.8 0.3 2 8.1 0.1 2.6 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 KXS17156.1 - 0.024 14.2 4.1 1 8.9 0.0 3.4 4 0 0 4 4 4 0 AAA domain NACHT PF05729.12 KXS17156.1 - 0.034 14.1 2.2 3.7 7.4 0.0 2.7 3 0 0 3 3 3 0 NACHT domain AAA_16 PF13191.6 KXS17156.1 - 0.034 14.5 5.5 5.2 7.4 0.0 3.4 2 1 1 3 3 3 0 AAA ATPase domain MeaB PF03308.16 KXS17156.1 - 0.042 12.8 6.2 0.38 9.7 0.5 3.0 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_15 PF13175.6 KXS17156.1 - 0.046 13.4 4.6 2 8.0 0.0 3.4 5 0 0 5 5 5 0 AAA ATPase domain NTPase_1 PF03266.15 KXS17156.1 - 0.049 13.6 0.4 6.3 6.7 0.1 3.0 2 0 0 2 2 2 0 NTPase AAA_14 PF13173.6 KXS17156.1 - 0.13 12.4 0.0 15 5.6 0.0 3.0 3 0 0 3 3 2 0 AAA domain Dynamin_N PF00350.23 KXS17156.1 - 0.16 12.0 0.0 0.16 12.0 0.0 2.8 4 0 0 4 4 4 0 Dynamin family AAA_28 PF13521.6 KXS17156.1 - 0.16 12.2 3.8 2.7 8.2 0.0 3.2 2 1 0 2 2 2 0 AAA domain DUF87 PF01935.17 KXS17156.1 - 5.8 6.9 10.5 9.7 6.2 0.2 3.7 3 1 0 3 3 3 0 Helicase HerA, central domain ABC2_membrane PF01061.24 KXS17157.1 - 5.3e-32 111.0 16.3 5.3e-32 111.0 16.3 2.1 3 0 0 3 3 2 1 ABC-2 type transporter ABC_tran PF00005.27 KXS17157.1 - 3e-23 82.8 0.0 5.7e-23 82.0 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KXS17157.1 - 2.3e-07 30.9 0.0 0.0091 15.8 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KXS17157.1 - 2e-05 24.2 0.3 4.6e-05 23.1 0.3 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 KXS17157.1 - 0.00015 22.2 0.1 0.00035 21.0 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 KXS17157.1 - 0.0007 19.1 0.0 0.11 12.0 0.0 2.2 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KXS17157.1 - 0.0033 17.3 0.1 0.0078 16.1 0.0 1.6 2 0 0 2 2 1 1 RsgA GTPase AAA_23 PF13476.6 KXS17157.1 - 0.0041 17.6 0.1 0.0067 17.0 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KXS17157.1 - 0.0095 16.2 0.0 0.023 15.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KXS17157.1 - 0.02 14.6 0.4 0.038 13.7 0.4 1.3 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KXS17157.1 - 0.025 14.2 0.2 0.051 13.1 0.2 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KXS17157.1 - 0.035 14.3 0.1 0.076 13.2 0.1 1.6 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 KXS17157.1 - 0.043 13.4 0.1 0.068 12.7 0.1 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain PDR_CDR PF06422.12 KXS17157.1 - 0.071 13.0 0.1 0.19 11.7 0.1 1.7 1 0 0 1 1 1 0 CDR ABC transporter T2SSE PF00437.20 KXS17157.1 - 0.14 11.2 0.1 0.21 10.6 0.1 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA PF00004.29 KXS17157.1 - 0.14 12.6 0.0 0.65 10.4 0.1 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MobB PF03205.14 KXS17157.1 - 0.17 11.8 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B IstB_IS21 PF01695.17 KXS17157.1 - 0.22 11.3 0.1 24 4.6 0.1 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein ABC2_membrane_3 PF12698.7 KXS17157.1 - 2.4 7.2 27.4 0.039 13.1 20.0 1.9 2 0 0 2 2 2 0 ABC-2 family transporter protein NPP1 PF05630.11 KXS17158.1 - 5.3e-38 131.1 0.0 6.3e-38 130.9 0.0 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) Glyco_hydro_114 PF03537.13 KXS17159.1 - 3.4e-69 232.7 0.0 4.3e-69 232.4 0.0 1.0 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 WD40 PF00400.32 KXS17160.1 - 3.6e-47 157.3 20.0 5e-09 36.6 0.1 7.9 7 1 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.10 KXS17160.1 - 2.9e-22 78.7 6.9 4.2e-22 78.2 6.9 1.2 1 0 0 1 1 1 1 Tup N-terminal ANAPC4_WD40 PF12894.7 KXS17160.1 - 7e-16 58.3 1.4 2.5e-05 24.5 0.0 5.2 3 2 3 6 6 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KXS17160.1 - 1.4e-08 34.1 2.2 0.068 12.1 0.0 5.4 3 2 3 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KXS17160.1 - 2.9e-05 22.9 0.1 1.8 7.1 0.0 4.6 4 1 1 5 5 5 1 Nucleoporin Nup120/160 WD40_like PF17005.5 KXS17160.1 - 0.0008 18.8 0.0 0.42 9.9 0.0 3.2 3 1 1 4 4 4 1 WD40-like domain PD40 PF07676.12 KXS17160.1 - 0.014 15.3 0.2 17 5.5 0.0 3.9 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat CEP63 PF17045.5 KXS17160.1 - 0.016 15.1 2.5 0.023 14.6 2.5 1.2 1 0 0 1 1 1 0 Centrosomal protein of 63 kDa ECM11 PF15463.6 KXS17160.1 - 0.019 15.5 2.4 0.043 14.4 2.4 1.5 1 0 0 1 1 1 0 Extracellular mutant protein 11 PALB2_WD40 PF16756.5 KXS17160.1 - 0.02 13.8 0.2 0.7 8.8 0.0 2.6 3 0 0 3 3 3 0 Partner and localizer of BRCA2 WD40 domain BicD PF09730.9 KXS17160.1 - 0.029 12.8 0.5 0.041 12.3 0.5 1.1 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D Nuc_N PF14448.6 KXS17160.1 - 0.041 13.7 0.1 8.3 6.4 0.0 3.1 3 0 0 3 3 3 0 Nuclease N terminal Nbas_N PF15492.6 KXS17160.1 - 0.068 12.5 0.0 4.5 6.5 0.0 2.3 2 0 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal Uso1_p115_C PF04871.13 KXS17160.1 - 0.083 13.3 1.6 0.14 12.5 1.6 1.2 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region CREPT PF16566.5 KXS17160.1 - 0.15 12.2 3.8 0.27 11.4 3.8 1.3 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour Nucleoporin_N PF08801.11 KXS17160.1 - 0.16 10.7 0.1 1.7 7.3 0.0 2.5 1 1 1 3 3 3 0 Nup133 N terminal like Spc7 PF08317.11 KXS17160.1 - 0.21 10.4 2.3 0.31 9.9 2.3 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Golgin_A5 PF09787.9 KXS17160.1 - 0.26 10.7 4.0 0.38 10.2 4.0 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 FUSC PF04632.12 KXS17160.1 - 6.9 5.1 6.1 9.9 4.6 6.1 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Peptidase_M20 PF01546.28 KXS17161.1 - 6.2e-27 94.6 0.1 7.8e-27 94.3 0.1 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KXS17161.1 - 6.4e-12 45.3 0.1 1.3e-11 44.3 0.1 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain CooT PF10133.9 KXS17161.1 - 0.2 12.0 0.1 0.4 11.0 0.1 1.4 1 0 0 1 1 1 0 CO dehydrogenase accessory protein CooT Yip1 PF04893.17 KXS17162.1 - 1e-09 38.3 11.5 1e-09 38.3 11.5 1.7 1 1 1 2 2 2 1 Yip1 domain MFS_1 PF07690.16 KXS17163.1 - 2.7e-30 105.5 51.3 4.8e-19 68.5 20.2 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily ApoO PF09769.9 KXS17163.1 - 0.042 13.8 0.2 0.25 11.3 0.2 2.2 1 1 0 1 1 1 0 Apolipoprotein O AICARFT_IMPCHas PF01808.18 KXS17164.1 - 2.3e-90 303.0 0.0 3e-90 302.7 0.0 1.1 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 KXS17164.1 - 1.7e-25 89.0 0.0 3.3e-25 88.1 0.0 1.5 1 0 0 1 1 1 1 MGS-like domain Ribosomal_S11 PF00411.19 KXS17164.1 - 0.14 12.6 0.4 0.84 10.1 0.0 2.3 2 0 0 2 2 2 0 Ribosomal protein S11 EF-hand_5 PF13202.6 KXS17165.1 - 0.079 12.5 0.5 0.16 11.5 0.5 1.5 1 0 0 1 1 1 0 EF hand Thioredoxin PF00085.20 KXS17166.1 - 0.0014 18.6 0.0 0.0025 17.8 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Tti2 PF10521.9 KXS17167.1 - 4.3e-20 72.4 0.0 1e-19 71.2 0.0 1.6 1 0 0 1 1 1 1 Tti2 family MMS19_C PF12460.8 KXS17167.1 - 0.00014 21.1 1.5 0.00053 19.2 2.0 1.7 2 0 0 2 2 2 1 RNAPII transcription regulator C-terminal HEAT_EZ PF13513.6 KXS17167.1 - 0.032 14.8 4.5 0.079 13.5 0.0 3.5 3 0 0 3 3 3 0 HEAT-like repeat HEAT PF02985.22 KXS17167.1 - 0.33 11.3 0.1 0.33 11.3 0.1 3.1 3 0 0 3 3 3 0 HEAT repeat SRP14 PF02290.15 KXS17168.1 - 1.1e-23 83.4 0.0 4.6e-22 78.2 0.0 2.4 1 1 0 1 1 1 1 Signal recognition particle 14kD protein LSM PF01423.22 KXS17169.1 - 4.7e-17 61.4 0.1 6.2e-17 61.1 0.1 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KXS17169.1 - 0.099 12.8 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain Gemin7 PF11095.8 KXS17169.1 - 0.11 12.4 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 Gem-associated protein 7 (Gemin7) Tetraspanin PF00335.20 KXS17170.1 - 7.1e-18 65.2 0.4 9.5e-18 64.7 0.4 1.1 1 0 0 1 1 1 1 Tetraspanin family DUF2244 PF10003.9 KXS17170.1 - 0.091 12.4 0.0 0.091 12.4 0.0 2.6 2 1 1 3 3 3 0 Integral membrane protein (DUF2244) Radial_spoke PF04712.12 KXS17171.1 - 5.1e-17 62.0 0.0 4.4e-05 22.6 0.0 3.1 3 0 0 3 3 3 3 Radial spokehead-like protein Myc_N PF01056.18 KXS17173.1 - 0.27 11.1 5.2 0.37 10.7 5.0 1.3 1 1 0 1 1 1 0 Myc amino-terminal region CBS PF00571.28 KXS17174.1 - 2.3e-08 34.3 0.4 0.042 14.3 0.0 3.7 4 0 0 4 4 4 3 CBS domain Rieske PF00355.26 KXS17174.1 - 0.18 11.8 0.0 0.41 10.6 0.0 1.5 1 0 0 1 1 1 0 Rieske [2Fe-2S] domain TLD PF07534.16 KXS17175.1 - 1.3e-32 112.9 0.0 1.7e-32 112.5 0.0 1.1 1 0 0 1 1 1 1 TLD Peptidase_C13 PF01650.18 KXS17176.1 - 9.2e-41 140.0 0.0 1.2e-40 139.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase C13 family Pkinase_Tyr PF07714.17 KXS17180.1 - 8.5e-06 25.2 0.0 1e-05 25.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXS17180.1 - 0.0001 21.8 0.0 0.00011 21.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Methyltranf_PUA PF13636.6 KXS17180.1 - 0.031 14.2 0.0 0.068 13.2 0.0 1.6 1 0 0 1 1 1 0 RNA-binding PUA-like domain of methyltransferase RsmF APH PF01636.23 KXS17180.1 - 0.17 11.8 0.0 0.37 10.7 0.0 1.3 1 1 0 1 1 1 0 Phosphotransferase enzyme family GPR_Gpa2_C PF11970.8 KXS17181.1 - 0.025 14.7 0.0 0.14 12.3 0.0 2.0 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 C-term DAO PF01266.24 KXS17182.1 - 5.4e-35 121.6 0.0 8.7e-35 120.9 0.0 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXS17182.1 - 1.9e-07 31.2 0.1 4.9e-07 29.9 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXS17182.1 - 1.2e-06 28.0 0.4 0.0023 17.2 0.0 2.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXS17182.1 - 4e-06 27.3 0.7 0.00016 22.1 0.3 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KXS17182.1 - 5.9e-05 22.1 0.1 0.041 12.7 0.0 2.1 2 0 0 2 2 2 2 Tryptophan halogenase FAD_binding_2 PF00890.24 KXS17182.1 - 6.2e-05 22.3 4.1 0.0015 17.7 4.1 2.2 1 1 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.24 KXS17182.1 - 0.00021 20.7 0.1 0.15 11.3 0.2 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.19 KXS17182.1 - 0.00036 19.9 0.3 0.0006 19.2 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 KXS17182.1 - 0.0024 17.9 0.1 0.5 10.3 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding HI0933_like PF03486.14 KXS17182.1 - 0.0035 16.1 0.6 0.021 13.5 0.3 2.0 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 KXS17182.1 - 0.0046 16.1 0.3 0.18 10.9 0.1 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 KXS17182.1 - 0.0068 15.7 0.8 0.012 14.9 0.2 1.7 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 KXS17182.1 - 0.0081 16.4 0.0 0.018 15.3 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain Pyr_redox_3 PF13738.6 KXS17182.1 - 0.0084 15.4 0.1 0.016 14.5 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 KXS17182.1 - 0.0093 16.0 0.0 0.97 9.5 0.0 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.17 KXS17182.1 - 0.0099 15.1 0.3 0.017 14.3 0.3 1.4 1 0 0 1 1 1 1 Thi4 family 3HCDH_N PF02737.18 KXS17182.1 - 0.017 15.0 0.0 0.029 14.3 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 KXS17182.1 - 0.068 12.7 0.1 0.24 11.0 0.1 1.8 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_oxidored PF12831.7 KXS17182.1 - 0.1 11.9 0.1 0.14 11.5 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase NmrA PF05368.13 KXS17185.1 - 3.2e-46 157.8 0.0 3.8e-46 157.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXS17185.1 - 8.5e-19 68.2 0.0 2.1e-18 66.8 0.0 1.6 2 0 0 2 2 2 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KXS17185.1 - 0.00026 20.1 0.0 0.00069 18.7 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KXS17185.1 - 0.00073 19.1 0.2 0.0052 16.3 0.2 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KXS17185.1 - 0.049 13.5 0.2 0.54 10.1 0.0 2.3 2 0 0 2 2 2 0 KR domain TrkA_N PF02254.18 KXS17185.1 - 0.085 13.1 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain Fer2_4 PF13510.6 KXS17185.1 - 0.13 12.3 0.2 0.79 9.8 0.0 2.1 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain ADH_zinc_N PF00107.26 KXS17186.1 - 1.1e-06 28.7 0.2 2.1e-06 27.8 0.2 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXS17186.1 - 0.029 14.2 0.0 0.065 13.1 0.0 1.7 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KXS17186.1 - 0.12 13.5 0.3 22 6.1 0.0 2.3 1 1 0 2 2 2 0 Zinc-binding dehydrogenase Cyt-b5 PF00173.28 KXS17187.1 - 5.3e-18 64.9 0.2 3.2e-17 62.4 0.0 2.2 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain adh_short PF00106.25 KXS17187.1 - 2.4e-05 23.9 0.0 0.049 13.1 0.0 2.5 2 0 0 2 2 2 2 short chain dehydrogenase DUF4334 PF14232.6 KXS17187.1 - 0.13 12.2 0.0 0.31 11.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4334) TFIIB PF00382.19 KXS17188.1 - 6.1e-27 93.5 1.5 1.5e-19 69.8 0.3 2.2 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 KXS17188.1 - 3.2e-10 39.3 0.6 6.3e-10 38.4 0.6 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding RB_B PF01857.20 KXS17188.1 - 0.00018 21.5 0.1 0.0019 18.2 0.0 2.0 1 1 1 2 2 2 1 Retinoblastoma-associated protein B domain Zn-ribbon_8 PF09723.10 KXS17188.1 - 0.097 12.8 0.4 0.19 11.8 0.4 1.5 1 0 0 1 1 1 0 Zinc ribbon domain DUF1664 PF07889.12 KXS17188.1 - 0.12 12.4 0.2 0.45 10.6 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Cohesin_load PF10345.9 KXS17189.1 - 3.7e-21 75.2 0.0 5.5e-17 61.5 1.4 2.2 2 0 0 2 2 2 2 Cohesin loading factor TPR_MalT PF17874.1 KXS17189.1 - 0.00064 19.2 11.7 0.21 10.9 0.0 3.5 3 1 0 3 3 3 3 MalT-like TPR region RepB PF07506.11 KXS17189.1 - 0.063 13.4 0.1 0.18 11.9 0.0 1.7 2 0 0 2 2 2 0 RepB plasmid partitioning protein WD40 PF00400.32 KXS17190.1 - 0.16 12.9 4.4 9.6 7.3 0.0 3.8 5 0 0 5 5 5 0 WD domain, G-beta repeat Ank_2 PF12796.7 KXS17192.1 - 4e-35 120.3 2.2 1.2e-12 48.3 0.0 3.6 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXS17192.1 - 4e-21 72.8 6.0 0.00012 22.2 0.0 6.9 7 1 1 8 8 8 4 Ankyrin repeat Ank_4 PF13637.6 KXS17192.1 - 3e-16 59.5 4.8 2.7e-08 34.2 0.1 5.6 2 2 4 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 KXS17192.1 - 3.1e-15 55.8 9.9 0.002 18.5 0.0 6.4 6 1 1 7 7 7 4 Ankyrin repeat Ank_5 PF13857.6 KXS17192.1 - 1.5e-14 53.8 4.4 0.014 15.7 0.0 6.1 4 1 2 6 6 6 5 Ankyrin repeats (many copies) HTH_22 PF13309.6 KXS17192.1 - 0.018 15.1 0.9 0.1 12.7 0.0 2.6 4 0 0 4 4 4 0 HTH domain DUF249 PF03158.13 KXS17192.1 - 0.1 12.3 0.0 1.5 8.5 0.0 2.3 2 0 0 2 2 2 0 Multigene family 530 protein DUF3447 PF11929.8 KXS17192.1 - 0.19 11.7 0.0 11 6.1 0.0 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF3447) F-box PF00646.33 KXS17193.1 - 0.00022 21.0 0.0 0.00047 20.0 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KXS17193.1 - 0.0015 18.4 0.2 0.0039 17.0 0.0 1.8 2 0 0 2 2 2 1 F-box-like SH3_9 PF14604.6 KXS17195.1 - 3.5e-09 36.4 0.1 6.4e-09 35.5 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXS17195.1 - 8.6e-09 34.9 0.0 1.4e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KXS17195.1 - 1.8e-05 24.3 0.0 4.5e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SKG6 PF08693.10 KXS17195.1 - 0.00087 18.7 2.5 0.0026 17.1 2.5 1.8 1 0 0 1 1 1 1 Transmembrane alpha-helix domain CcmD PF04995.14 KXS17195.1 - 0.5 10.5 2.8 0.88 9.7 2.8 1.4 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) YtxH PF12732.7 KXS17195.1 - 7.9 7.1 7.5 14 6.3 7.5 1.3 1 0 0 1 1 1 0 YtxH-like protein BTG PF07742.12 KXS17196.1 - 5.5e-22 77.8 0.0 1.2e-21 76.7 0.0 1.5 1 0 0 1 1 1 1 BTG family HpcH_HpaI PF03328.14 KXS17201.1 - 0.023 13.8 0.0 0.028 13.6 0.0 1.1 1 0 0 1 1 1 0 HpcH/HpaI aldolase/citrate lyase family HpcH_HpaI PF03328.14 KXS17202.1 - 1.1e-29 103.2 0.0 1.4e-29 102.9 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family LPP PF04728.13 KXS17203.1 - 0.13 12.7 0.1 0.48 10.8 0.0 1.9 2 1 0 2 2 2 0 Lipoprotein leucine-zipper H2TH PF06831.14 KXS17204.1 - 1e-22 79.9 0.0 2.2e-22 78.9 0.0 1.6 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain SAP PF02037.27 KXS17204.1 - 3.3e-07 29.9 2.3 7.1e-07 28.8 2.3 1.5 1 0 0 1 1 1 1 SAP domain Fapy_DNA_glyco PF01149.24 KXS17204.1 - 1.7e-06 28.6 0.1 6.5e-06 26.8 0.0 2.1 2 0 0 2 2 2 1 Formamidopyrimidine-DNA glycosylase N-terminal domain C1_1 PF00130.22 KXS17204.1 - 0.009 15.9 5.1 0.016 15.1 5.1 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) HeH PF12949.7 KXS17204.1 - 0.036 13.8 0.3 0.1 12.3 0.3 1.7 1 1 0 1 1 1 0 HeH/LEM domain SAD_SRA PF02182.17 KXS17204.1 - 0.2 11.4 0.7 0.47 10.1 0.7 1.6 1 0 0 1 1 1 0 SAD/SRA domain zf-C2H2 PF00096.26 KXS17205.1 - 0.058 13.9 0.6 0.11 13.0 0.6 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf_C2H2_6 PF18450.1 KXS17205.1 - 0.51 10.1 3.0 1 9.1 3.0 1.4 1 0 0 1 1 1 0 Zinc Finger domain NUDIX_2 PF13869.6 KXS17206.1 - 9.1e-76 253.6 0.0 1e-75 253.5 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase Histone PF00125.24 KXS17207.1 - 5.1e-46 156.3 1.1 5.8e-46 156.1 1.1 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 KXS17207.1 - 0.00046 20.3 0.1 0.00068 19.7 0.1 1.4 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KXS17207.1 - 0.003 17.9 0.0 0.0045 17.3 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 KXS17207.1 - 0.0071 16.4 0.0 0.0094 16.0 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit CBFD_NFYB_HMF PF00808.23 KXS17207.1 - 0.066 13.5 0.3 0.16 12.3 0.3 1.6 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF4658 PF15555.6 KXS17207.1 - 0.14 12.2 2.7 0.097 12.8 1.2 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4658) MoCF_biosynth PF00994.24 KXS17208.1 - 1.4e-40 138.3 1.7 9.9e-25 86.9 0.0 3.3 2 1 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.17 KXS17208.1 - 4.5e-35 120.7 4.6 1e-34 119.6 4.6 1.6 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.15 KXS17208.1 - 9.9e-10 38.5 0.4 4.1e-09 36.5 0.4 2.2 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) DUF4621 PF15414.6 KXS17208.1 - 0.18 10.7 0.2 0.28 10.0 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4621) Mei5 PF10376.9 KXS17209.1 - 2.7e-07 30.7 0.0 1.5e-06 28.2 0.0 2.1 3 0 0 3 3 3 1 Double-strand recombination repair protein QWRF PF04484.12 KXS17209.1 - 0.18 11.5 4.6 0.48 10.1 4.6 1.7 1 1 0 1 1 1 0 QWRF family Aldo_ket_red PF00248.21 KXS17210.1 - 5.6e-53 180.0 0.1 1.2e-51 175.7 0.1 2.5 1 1 0 1 1 1 1 Aldo/keto reductase family Ank_2 PF12796.7 KXS17211.1 - 4.8e-16 59.1 1.2 3.6e-06 27.5 0.0 2.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXS17211.1 - 1.9e-13 50.3 2.2 1.5e-09 37.9 0.4 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXS17211.1 - 1.6e-08 34.9 2.3 5.6e-07 30.0 0.1 3.1 3 1 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXS17211.1 - 2.1e-06 27.6 2.4 0.00045 20.4 0.0 3.8 4 0 0 4 4 4 1 Ankyrin repeat Ank PF00023.30 KXS17211.1 - 2.8e-05 24.4 6.6 0.0032 17.9 0.0 4.7 5 0 0 5 5 5 1 Ankyrin repeat RNase_T PF00929.24 KXS17212.1 - 0.15 12.6 0.1 0.2 12.2 0.1 1.2 1 0 0 1 1 1 0 Exonuclease Gti1_Pac2 PF09729.9 KXS17216.1 - 0.34 11.0 4.8 0.79 9.8 4.8 1.5 1 1 0 1 1 1 0 Gti1/Pac2 family Proteasome PF00227.26 KXS17217.1 - 4.6e-29 101.3 0.1 5.2e-29 101.1 0.1 1.0 1 0 0 1 1 1 1 Proteasome subunit INCENP_ARK-bind PF03941.15 KXS17218.1 - 2.3e-10 40.2 0.9 5.1e-10 39.1 0.9 1.6 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region Peptidase_M14 PF00246.24 KXS17219.1 - 1.7e-36 126.5 0.1 3.9e-20 72.8 0.0 2.2 1 1 1 2 2 2 2 Zinc carboxypeptidase EF-hand_9 PF14658.6 KXS17219.1 - 0.17 12.2 0.1 0.48 10.8 0.1 1.7 1 0 0 1 1 1 0 EF-hand domain Vps26 PF03643.15 KXS17220.1 - 3.8e-122 406.6 1.9 4.5e-122 406.4 1.9 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 KXS17220.1 - 0.0013 18.8 1.1 0.23 11.5 0.1 3.1 2 1 1 3 3 3 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 KXS17220.1 - 0.0025 18.3 0.4 0.83 10.1 0.0 2.4 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain INCENP_ARK-bind PF03941.15 KXS17221.1 - 6.1e-12 45.3 0.2 1.7e-11 43.9 0.2 1.7 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region DUF4188 PF13826.6 KXS17222.1 - 1.3e-30 106.1 0.0 1.7e-30 105.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4188) Dehydratase_hem PF13816.6 KXS17222.1 - 0.00026 20.5 0.0 0.001 18.6 0.0 1.6 1 1 0 1 1 1 1 Haem-containing dehydratase tRNA-synt_1c PF00749.21 KXS17223.1 - 1.3e-105 352.8 0.0 1.8e-105 352.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 KXS17223.1 - 5.1e-35 120.9 0.2 1e-34 119.9 0.2 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_bind PF01588.20 KXS17223.1 - 6.1e-29 100.0 0.1 2.3e-28 98.1 0.0 2.0 2 0 0 2 2 2 1 Putative tRNA binding domain GST_C PF00043.25 KXS17223.1 - 0.00025 21.2 0.0 0.00076 19.7 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain tRNA-synt_1e PF01406.19 KXS17223.1 - 0.0023 17.3 0.1 0.0074 15.7 0.1 1.7 1 1 1 2 2 2 1 tRNA synthetases class I (C) catalytic domain GST_C_2 PF13410.6 KXS17223.1 - 0.014 15.4 0.1 0.034 14.2 0.1 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Bap31 PF05529.12 KXS17224.1 - 1.1e-07 31.7 0.4 1.6e-07 31.2 0.4 1.1 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region RRM_1 PF00076.22 KXS17227.1 - 4.2e-08 32.9 0.0 6.2e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 KXS17227.1 - 8.3e-08 32.7 12.4 8.3e-08 32.7 12.4 2.9 2 1 1 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 Cys_Met_Meta_PP PF01053.20 KXS17228.1 - 1.2e-146 488.1 0.0 6.2e-95 317.9 0.0 2.0 2 0 0 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KXS17228.1 - 0.028 13.6 0.0 0.044 12.9 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II DEC-1_N PF04625.13 KXS17228.1 - 0.26 10.3 1.0 0.38 9.7 1.0 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Abhydrolase_6 PF12697.7 KXS17229.1 - 6.1e-16 59.7 0.0 7.5e-16 59.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXS17229.1 - 6e-08 32.2 0.0 9.3e-08 31.6 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KXS17229.1 - 0.00023 20.9 0.0 0.0012 18.5 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 KXS17229.1 - 0.001 18.8 0.1 0.0026 17.5 0.1 1.6 1 1 0 1 1 1 1 Putative esterase N_NLPC_P60 PF12912.7 KXS17229.1 - 0.005 17.2 0.1 0.0083 16.5 0.1 1.3 1 0 0 1 1 1 1 NLPC_P60 stabilising domain, N term Peptidase_S9 PF00326.21 KXS17229.1 - 0.0059 16.1 0.0 0.01 15.4 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family 3HCDH_N PF02737.18 KXS17231.1 - 4.6e-59 199.3 2.3 6.4e-59 198.8 2.3 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KXS17231.1 - 2.2e-32 111.6 0.0 8e-22 77.7 0.0 3.0 2 1 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 KXS17231.1 - 0.00055 20.1 2.1 0.0016 18.7 2.1 1.8 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Pyr_redox_2 PF07992.14 KXS17231.1 - 0.014 14.7 0.0 0.022 14.0 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXS17231.1 - 0.046 14.3 0.6 0.11 13.1 0.6 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.17 KXS17231.1 - 0.15 12.6 2.6 0.47 11.1 2.3 2.1 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 KXS17231.1 - 0.17 11.2 0.2 0.33 10.3 0.2 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Acetyltransf_3 PF13302.7 KXS17232.1 - 7.6e-24 85.0 0.0 9.7e-24 84.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXS17232.1 - 1.6e-06 28.4 0.0 2.2e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 KXS17232.1 - 2.5e-06 27.7 0.0 4.4e-06 26.9 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KXS17232.1 - 0.00053 19.7 0.0 0.00075 19.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain AA_permease_2 PF13520.6 KXS17233.1 - 4.1e-50 170.9 49.3 5.1e-50 170.6 49.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXS17233.1 - 2.1e-13 49.7 40.5 2.8e-13 49.3 40.5 1.1 1 0 0 1 1 1 1 Amino acid permease SKG6 PF08693.10 KXS17234.1 - 0.023 14.1 0.1 0.05 13.0 0.1 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Nitrate_red_gam PF02665.14 KXS17234.1 - 0.046 13.2 0.0 0.085 12.4 0.0 1.4 1 0 0 1 1 1 0 Nitrate reductase gamma subunit Gram_pos_anchor PF00746.21 KXS17234.1 - 0.34 10.9 2.9 1.4 8.9 2.9 2.1 1 1 0 1 1 1 0 LPXTG cell wall anchor motif BAR PF03114.18 KXS17235.1 - 1.2e-26 93.8 0.1 1.6e-26 93.4 0.1 1.2 1 0 0 1 1 1 1 BAR domain Uds1 PF15456.6 KXS17235.1 - 0.01 16.0 3.0 0.095 12.9 0.6 2.4 2 0 0 2 2 2 0 Up-regulated During Septation Phasin PF05597.11 KXS17235.1 - 0.038 14.0 1.4 2.4 8.2 0.0 3.0 3 0 0 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) SKA2 PF16740.5 KXS17235.1 - 0.055 13.2 0.1 0.8 9.5 0.0 2.4 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 Vps5 PF09325.10 KXS17235.1 - 0.11 12.1 0.3 0.28 10.7 0.3 1.8 1 0 0 1 1 1 0 Vps5 C terminal like ATG16 PF08614.11 KXS17235.1 - 0.13 12.5 3.6 5.3 7.2 0.5 2.3 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Ribosomal_L44 PF00935.19 KXS17236.1 - 5e-38 129.4 12.1 7.3e-38 128.9 12.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 bVLRF1 PF18826.1 KXS17237.1 - 2.1e-51 173.7 0.0 3.8e-51 172.9 0.0 1.4 1 0 0 1 1 1 1 bacteroidetes VLRF1 release factor VATC PF18716.1 KXS17237.1 - 4.4e-07 29.7 2.1 5.3e-07 29.4 0.4 1.9 2 0 0 2 2 2 1 Vms1-associating treble clef domain Metallothio_Pro PF02069.16 KXS17237.1 - 0.00016 21.9 0.4 0.00026 21.1 0.4 1.4 1 0 0 1 1 1 1 Prokaryotic metallothionein Med19 PF10278.9 KXS17237.1 - 0.13 12.1 6.7 0.31 11.0 6.7 1.6 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Ank_5 PF13857.6 KXS17237.1 - 0.15 12.4 0.0 0.35 11.2 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Eapp_C PF10238.9 KXS17237.1 - 0.51 10.4 2.2 1.7 8.7 1.4 2.2 2 0 0 2 2 2 0 E2F-associated phosphoprotein FAM60A PF15396.6 KXS17237.1 - 1.6 8.6 5.6 0.66 9.9 1.1 2.4 2 0 0 2 2 2 0 Protein Family FAM60A Rtf2 PF04641.12 KXS17237.1 - 2 7.7 8.0 4.3 6.6 8.0 1.5 1 0 0 1 1 1 0 Rtf2 RING-finger Phage_Gp23 PF10669.9 KXS17237.1 - 3.2 8.1 12.6 6.3 7.1 12.6 1.4 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) UQ_con PF00179.26 KXS17238.1 - 4.8e-34 117.0 0.0 6.1e-34 116.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Ion_trans PF00520.31 KXS17239.1 - 8.3e-41 139.8 20.7 1e-40 139.5 20.7 1.1 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 KXS17239.1 - 2e-05 23.4 11.2 2e-05 23.4 11.2 1.7 1 1 1 2 2 2 1 Polycystin cation channel DUF2976 PF11190.8 KXS17239.1 - 0.0056 16.4 7.0 0.17 11.7 0.1 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF2976) ResB PF05140.14 KXS17239.1 - 0.097 11.4 0.0 0.17 10.6 0.0 1.3 1 0 0 1 1 1 0 ResB-like family TauD PF02668.16 KXS17240.1 - 1.5e-36 126.6 0.0 1.9e-36 126.2 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family ISN1 PF06437.11 KXS17242.1 - 4.5e-80 269.5 0.0 1.2e-79 268.1 0.0 1.6 1 1 0 1 1 1 1 IMP-specific 5'-nucleotidase YpzI PF14140.6 KXS17243.1 - 0.0083 15.9 1.2 0.024 14.4 1.2 1.8 1 0 0 1 1 1 1 YpzI-like protein zf_C2H2_ZHX PF18387.1 KXS17243.1 - 0.082 12.6 0.3 0.18 11.5 0.3 1.5 1 0 0 1 1 1 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-met PF12874.7 KXS17243.1 - 0.1 13.0 1.2 0.2 12.1 1.2 1.5 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KXS17243.1 - 0.25 11.4 1.1 0.41 10.7 1.1 1.3 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KXS17243.1 - 0.27 11.8 2.5 0.52 10.9 2.5 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type Ferric_reduct PF01794.19 KXS17244.1 - 6.6e-15 55.3 12.2 6.6e-15 55.3 12.2 2.5 1 1 1 2 2 2 2 Ferric reductase like transmembrane component TMEM174 PF15029.6 KXS17244.1 - 0.11 12.2 0.7 0.19 11.4 0.7 1.3 1 0 0 1 1 1 0 Transmembrane protein 174 DASH_Hsk3 PF08227.11 KXS17245.1 - 0.001 19.4 0.2 0.0025 18.2 0.2 1.7 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like MIP-T3_C PF17749.1 KXS17245.1 - 0.042 13.8 0.2 0.082 12.9 0.2 1.4 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 C-terminal region Filament PF00038.21 KXS17245.1 - 0.11 12.1 4.4 0.037 13.6 1.1 1.7 1 1 0 2 2 2 0 Intermediate filament protein DUF948 PF06103.11 KXS17245.1 - 0.12 12.6 1.1 0.19 12.0 0.4 1.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF2469 PF10611.9 KXS17245.1 - 0.16 12.5 0.1 0.34 11.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2469) LPP PF04728.13 KXS17245.1 - 0.27 11.6 0.2 0.27 11.6 0.2 2.4 3 0 0 3 3 3 0 Lipoprotein leucine-zipper FliJ PF02050.16 KXS17245.1 - 0.41 10.9 7.2 0.98 9.7 0.5 2.4 1 1 1 2 2 2 0 Flagellar FliJ protein HAUS-augmin3 PF14932.6 KXS17245.1 - 1.6 8.2 9.8 0.038 13.6 1.0 2.0 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 DDHD PF02862.17 KXS17246.1 - 4.2e-19 69.6 0.0 1.7e-17 64.4 0.0 2.8 1 1 0 1 1 1 1 DDHD domain LRR_1 PF00560.33 KXS17248.1 - 0.14 12.8 4.3 1.1e+02 4.0 0.0 5.5 6 1 0 6 6 6 0 Leucine Rich Repeat LRR_4 PF12799.7 KXS17248.1 - 2.3 8.8 10.8 31 5.1 0.9 5.4 5 3 2 7 7 7 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXS17248.1 - 2.9 7.7 8.4 15 5.4 0.3 4.3 5 1 1 6 6 6 0 Leucine rich repeat Glyoxalase PF00903.25 KXS17249.1 - 6.4e-05 23.1 0.0 0.00012 22.2 0.0 1.5 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Abhydrolase_1 PF00561.20 KXS17250.1 - 7.7e-08 32.3 0.1 0.0024 17.6 0.1 2.4 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXS17250.1 - 1.2e-07 31.2 0.0 0.00021 20.6 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 KXS17250.1 - 2.5e-06 27.3 0.3 0.00018 21.2 0.2 2.1 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.7 KXS17250.1 - 1.7e-05 25.5 1.1 0.0085 16.7 0.3 2.2 1 1 1 2 2 2 2 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KXS17250.1 - 2.1e-05 24.1 0.2 0.058 12.9 0.4 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family FSH1 PF03959.13 KXS17250.1 - 0.0024 17.5 0.0 0.0034 17.1 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Cutinase PF01083.22 KXS17250.1 - 0.043 13.8 0.0 0.064 13.2 0.0 1.2 1 0 0 1 1 1 0 Cutinase PE-PPE PF08237.11 KXS17250.1 - 0.095 12.2 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 PE-PPE domain Abhydrolase_5 PF12695.7 KXS17250.1 - 0.18 11.5 0.0 14 5.4 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase family B9-C2 PF07162.11 KXS17252.1 - 5.8e-20 72.2 0.0 1.5e-13 51.3 0.0 2.8 1 1 1 2 2 2 2 Ciliary basal body-associated, B9 protein WD40 PF00400.32 KXS17253.1 - 2.4e-07 31.3 5.8 0.96 10.4 0.1 5.3 4 1 0 4 4 4 4 WD domain, G-beta repeat SPRY PF00622.28 KXS17254.1 - 1.7e-07 31.4 0.0 2.7e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 SPRY domain 2OG-FeII_Oxy_3 PF13640.6 KXS17255.1 - 2.7e-06 28.2 0.0 6.6e-06 26.9 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Sulfatase PF00884.23 KXS17255.1 - 0.1 11.9 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Sulfatase Fructosamin_kin PF03881.14 KXS17256.1 - 2.5e-72 243.5 0.0 3e-72 243.3 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 KXS17256.1 - 1.7e-12 47.8 0.0 2.3e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family MHC_I PF00129.18 KXS17256.1 - 0.18 11.4 0.0 0.27 10.8 0.0 1.2 1 0 0 1 1 1 0 Class I Histocompatibility antigen, domains alpha 1 and 2 HNH PF01844.23 KXS17257.1 - 0.058 13.6 0.0 0.16 12.2 0.0 1.8 1 0 0 1 1 1 0 HNH endonuclease SlyX PF04102.12 KXS17260.1 - 0.017 15.8 6.0 0.017 15.8 6.0 3.2 1 1 2 3 3 3 0 SlyX ABC_tran_CTD PF16326.5 KXS17260.1 - 0.13 12.6 9.3 0.52 10.6 0.0 2.6 2 1 0 2 2 2 0 ABC transporter C-terminal domain DUF4407 PF14362.6 KXS17260.1 - 0.14 11.5 9.3 0.075 12.4 6.1 1.7 1 1 0 2 2 2 0 Domain of unknown function (DUF4407) FlaC_arch PF05377.11 KXS17260.1 - 0.56 10.6 4.6 17 5.9 0.7 2.9 3 0 0 3 3 2 0 Flagella accessory protein C (FlaC) Prefoldin_2 PF01920.20 KXS17260.1 - 0.61 10.1 10.9 0.61 10.1 0.2 3.7 1 1 2 3 3 3 0 Prefoldin subunit Lectin_N PF03954.14 KXS17260.1 - 0.68 9.7 3.1 2.4 7.9 3.1 2.0 1 1 0 1 1 1 0 Hepatic lectin, N-terminal domain DUF3802 PF12290.8 KXS17260.1 - 1.1 9.7 3.9 0.47 11.0 1.1 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3802) Spc7 PF08317.11 KXS17260.1 - 1.3 7.9 15.1 1.9 7.3 15.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein FlxA PF14282.6 KXS17260.1 - 2.1 8.4 6.4 5.8 7.0 2.0 2.5 2 1 0 2 2 2 0 FlxA-like protein UPF0242 PF06785.11 KXS17260.1 - 2.9 7.9 16.6 10 6.2 16.6 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus YabA PF06156.13 KXS17260.1 - 4.6 7.9 13.6 6.8 7.4 5.4 2.5 1 1 1 2 2 2 0 Initiation control protein YabA Uds1 PF15456.6 KXS17260.1 - 6.2 7.0 17.2 48 4.1 17.2 2.0 1 1 0 1 1 1 0 Up-regulated During Septation Asp-B-Hydro_N PF05279.11 KXS17260.1 - 7.5 6.5 9.3 12 5.9 9.3 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region CorA PF01544.18 KXS17260.1 - 8.1 5.7 11.5 11 5.2 11.5 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein SOAR PF16533.5 KXS17260.1 - 8.5 6.4 10.3 1.6 8.7 2.7 2.5 1 1 1 2 2 2 0 STIM1 Orai1-activating region DUF4200 PF13863.6 KXS17260.1 - 9 6.7 16.3 7.1 7.1 0.1 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) P5-ATPase PF12409.8 KXS17261.1 - 9.2e-22 77.5 0.0 3.5e-20 72.4 0.0 3.3 2 1 0 2 2 2 1 P5-type ATPase cation transporter E1-E2_ATPase PF00122.20 KXS17261.1 - 9.2e-17 61.1 2.0 7e-07 28.9 0.0 3.9 4 0 0 4 4 4 2 E1-E2 ATPase Hydrolase PF00702.26 KXS17261.1 - 1.9e-11 44.7 0.0 0.00038 20.8 0.0 3.3 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.21 KXS17261.1 - 3.6e-05 23.6 9.6 8.6e-05 22.3 9.6 1.6 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Cation_ATPase_N PF00690.26 KXS17261.1 - 7.1e-05 22.4 0.0 0.00016 21.3 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus DUF1418 PF07214.12 KXS17261.1 - 0.84 9.5 3.0 14 5.6 0.2 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1418) Methyltransf_21 PF05050.12 KXS17262.1 - 0.0043 17.1 0.0 0.0053 16.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain zf-C2H2 PF00096.26 KXS17263.1 - 2.2e-05 24.7 4.8 0.015 15.8 0.5 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_aberr PF17017.5 KXS17263.1 - 0.0004 20.6 3.6 0.21 11.7 0.3 2.7 2 1 1 3 3 3 2 Aberrant zinc-finger zf-C2H2_4 PF13894.6 KXS17263.1 - 0.023 15.5 13.2 0.16 12.9 0.3 3.9 3 0 0 3 3 3 0 C2H2-type zinc finger FOXP-CC PF16159.5 KXS17263.1 - 0.036 14.7 4.8 0.21 12.2 0.0 3.2 2 1 1 3 3 3 0 FOXP coiled-coil domain zf_Hakai PF18408.1 KXS17263.1 - 0.17 11.6 2.8 3.8 7.3 0.5 2.6 2 0 0 2 2 2 0 C2H2 Hakai zinc finger domain LAP2alpha PF11560.8 KXS17263.1 - 0.22 10.9 3.2 0.37 10.2 3.2 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 2 alpha SAPS PF04499.15 KXS17264.1 - 3.1e-36 125.2 0.0 1.7e-27 96.4 0.0 4.2 4 0 0 4 4 4 4 SIT4 phosphatase-associated protein AA_permease_2 PF13520.6 KXS17265.1 - 4e-20 72.1 43.7 1.7e-11 43.6 31.5 3.0 2 1 0 2 2 2 2 Amino acid permease AA_permease PF00324.21 KXS17265.1 - 7.2e-08 31.5 0.7 7.2e-08 31.5 0.7 3.2 2 1 1 3 3 3 2 Amino acid permease Phage_holin_3_6 PF07332.11 KXS17265.1 - 0.34 11.0 17.3 0.94 9.5 0.1 4.4 3 1 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III TMEM208_SND2 PF05620.11 KXS17265.1 - 1.9 8.3 5.0 1 9.1 0.0 2.8 2 0 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 LSM PF01423.22 KXS17266.1 - 1.8e-19 69.2 0.1 2e-19 69.0 0.1 1.1 1 0 0 1 1 1 1 LSM domain Putative_PNPOx PF01243.20 KXS17267.1 - 6.4e-09 35.9 0.0 9.9e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase F-box PF00646.33 KXS17268.1 - 0.029 14.3 0.4 0.051 13.5 0.4 1.5 1 0 0 1 1 1 0 F-box domain 7tm_3 PF00003.22 KXS17270.1 - 3.4e-33 115.3 12.3 5.2e-33 114.7 12.3 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR HCV_core PF01542.18 KXS17270.1 - 0.98 9.9 3.9 0.47 10.9 0.8 2.1 2 0 0 2 2 2 0 Hepatitis C virus core protein DUF1459 PF07312.11 KXS17270.1 - 1.7 9.0 5.2 0.59 10.4 0.3 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1459) Zip PF02535.22 KXS17271.1 - 4.2e-10 39.4 22.2 3.9e-09 36.2 6.6 3.1 2 1 0 2 2 2 2 ZIP Zinc transporter DUF4050 PF13259.6 KXS17271.1 - 0.043 14.1 0.0 0.082 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) Acetyltransf_1 PF00583.25 KXS17272.1 - 9.9e-06 25.8 0.0 1.3e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_CG PF14542.6 KXS17272.1 - 0.069 13.3 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_7 PF13508.7 KXS17272.1 - 0.073 13.5 0.0 0.13 12.7 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KXS17272.1 - 0.19 11.7 0.0 0.3 11.0 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain MFS_1 PF07690.16 KXS17274.1 - 1.5e-25 89.9 54.0 1.2e-18 67.2 22.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1622 PF07784.11 KXS17274.1 - 0.041 13.8 0.1 0.09 12.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1622) Chromate_transp PF02417.15 KXS17275.1 - 1.5e-54 184.4 40.8 2e-33 115.7 14.0 2.8 3 0 0 3 3 3 2 Chromate transporter SWIRM PF04433.17 KXS17276.1 - 4.3e-10 39.8 0.0 7.2e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 SWIRM domain LRR_6 PF13516.6 KXS17278.1 - 1.1e-14 53.1 5.2 0.001 18.9 0.0 6.2 6 0 0 6 6 6 3 Leucine Rich repeat F-box-like PF12937.7 KXS17278.1 - 0.00042 20.1 0.0 0.00097 19.0 0.0 1.6 1 0 0 1 1 1 1 F-box-like LRR_1 PF00560.33 KXS17278.1 - 3.3 8.6 8.8 1.9e+02 3.2 0.0 5.6 6 1 0 6 6 6 0 Leucine Rich Repeat HSP70 PF00012.20 KXS17279.1 - 5.5e-120 401.3 0.0 4.7e-119 398.3 0.0 2.2 1 1 0 1 1 1 1 Hsp70 protein Ribosomal_S5_C PF03719.15 KXS17280.1 - 1.1e-23 82.5 0.1 1.7e-23 81.9 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 KXS17280.1 - 1.8e-15 56.7 0.2 1.8e-15 56.7 0.2 2.2 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain FoP_duplication PF13865.6 KXS17280.1 - 0.11 13.0 17.6 0.2 12.2 17.6 1.3 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 V-SNARE_C PF12352.8 KXS17282.1 - 6.1e-08 32.8 0.0 1e-06 28.9 0.0 2.3 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Vir_act_alpha_C PF10400.9 KXS17282.1 - 0.0038 17.9 0.0 3.3 8.4 0.0 3.4 2 2 1 3 3 3 2 Virulence activator alpha C-term DUF4201 PF13870.6 KXS17282.1 - 0.2 11.4 1.6 0.42 10.3 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) Aminotran_3 PF00202.21 KXS17286.1 - 2.5e-111 372.2 0.0 3.3e-111 371.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III MscL PF01741.18 KXS17287.1 - 2.8e-11 43.8 0.0 3.9e-11 43.3 0.0 1.2 1 0 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL zf_C2H2_13 PF18508.1 KXS17287.1 - 0.0086 15.6 0.8 0.024 14.2 0.8 1.8 1 0 0 1 1 1 1 Zinc finger domain DZR PF12773.7 KXS17287.1 - 0.031 14.3 0.5 0.051 13.6 0.5 1.2 1 0 0 1 1 1 0 Double zinc ribbon UPF0547 PF10571.9 KXS17287.1 - 0.041 14.0 3.3 0.06 13.4 3.3 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 DUF2207 PF09972.9 KXS17287.1 - 0.19 10.5 0.0 0.24 10.1 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) LapA_dom PF06305.11 KXS17287.1 - 1 9.2 4.2 0.87 9.5 0.4 2.1 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain PspC PF04024.12 KXS17287.1 - 7.1 6.5 6.0 51 3.8 0.1 2.3 2 0 0 2 2 2 0 PspC domain MscL PF01741.18 KXS17288.1 - 3.3e-10 40.3 0.3 5.3e-10 39.6 0.0 1.4 2 0 0 2 2 2 1 Large-conductance mechanosensitive channel, MscL DUF883 PF05957.13 KXS17288.1 - 0.0057 17.2 0.0 0.013 16.1 0.0 1.5 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF883) UPF0547 PF10571.9 KXS17288.1 - 0.014 15.5 5.5 0.021 14.9 5.5 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 zf-C3HC4_3 PF13920.6 KXS17288.1 - 0.056 13.3 1.0 0.083 12.8 1.0 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_2 PF13240.6 KXS17288.1 - 0.063 13.0 1.3 0.11 12.2 1.3 1.4 1 0 0 1 1 1 0 zinc-ribbon domain DUF4420 PF14390.6 KXS17288.1 - 0.065 12.5 0.0 0.093 12.0 0.0 1.2 1 0 0 1 1 1 0 Putative PD-(D/E)XK family member, (DUF4420) DZR PF12773.7 KXS17288.1 - 0.075 13.1 1.4 0.12 12.4 1.4 1.3 1 0 0 1 1 1 0 Double zinc ribbon 3HCDH_N PF02737.18 KXS17288.1 - 0.079 12.8 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain zf-C3HC4_2 PF13923.6 KXS17288.1 - 0.2 11.5 1.5 0.3 11.0 1.5 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) YtxH PF12732.7 KXS17288.1 - 0.37 11.4 0.1 0.37 11.4 0.1 2.1 3 0 0 3 3 1 0 YtxH-like protein LapA_dom PF06305.11 KXS17288.1 - 0.43 10.4 7.5 2.5 8.0 0.4 2.5 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain 3Beta_HSD PF01073.19 KXS17289.1 - 2.2e-21 76.1 0.0 2.8e-21 75.8 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KXS17289.1 - 2.3e-18 66.6 0.0 2.5e-18 66.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXS17289.1 - 1.2e-13 51.2 0.0 1.8e-13 50.6 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KXS17289.1 - 1.4e-12 47.3 0.6 5.7e-08 32.2 0.0 2.5 2 1 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 KXS17289.1 - 1.6e-11 43.9 0.0 3.8e-11 42.6 0.0 1.5 1 1 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KXS17289.1 - 1.6e-09 37.3 0.0 3.8e-08 32.8 0.0 2.3 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 KXS17289.1 - 0.0026 17.7 0.2 0.017 15.0 0.1 2.2 2 1 0 2 2 2 1 KR domain Methyltransf_33 PF10017.9 KXS17290.1 - 1.4e-87 293.8 0.0 3.7e-86 289.1 0.0 2.0 1 1 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.16 KXS17290.1 - 4.2e-19 69.1 0.4 1.2e-18 67.6 0.4 1.8 1 1 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.7 KXS17290.1 - 0.0031 18.0 2.5 0.01 16.4 1.4 2.5 1 1 1 2 2 2 1 DinB superfamily GAS PF13851.6 KXS17291.1 - 0.00029 20.2 1.2 0.00036 20.0 0.7 1.4 1 1 0 1 1 1 1 Growth-arrest specific micro-tubule binding bZIP_1 PF00170.21 KXS17291.1 - 0.00038 20.5 1.9 0.3 11.2 0.1 2.4 2 0 0 2 2 2 2 bZIP transcription factor DivIC PF04977.15 KXS17291.1 - 0.0022 17.7 0.7 0.97 9.3 0.0 2.6 1 1 1 2 2 2 1 Septum formation initiator SH3_1 PF00018.28 KXS17291.1 - 0.0032 17.1 0.0 0.006 16.2 0.0 1.5 1 0 0 1 1 1 1 SH3 domain HALZ PF02183.18 KXS17291.1 - 0.0034 17.6 0.7 0.6 10.4 0.0 2.7 1 1 2 3 3 3 1 Homeobox associated leucine zipper TSC22 PF01166.18 KXS17291.1 - 0.004 17.4 1.2 2.8 8.3 0.1 2.8 2 1 1 3 3 2 1 TSC-22/dip/bun family Spc7 PF08317.11 KXS17291.1 - 0.01 14.7 5.4 0.015 14.2 5.4 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein GIT_CC PF16559.5 KXS17291.1 - 0.011 15.5 5.4 2 8.4 0.4 3.3 1 1 1 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF4201 PF13870.6 KXS17291.1 - 0.012 15.4 4.4 0.018 14.8 4.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) DUF4407 PF14362.6 KXS17291.1 - 0.015 14.7 5.7 0.022 14.1 5.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Atg14 PF10186.9 KXS17291.1 - 0.016 14.3 5.5 0.023 13.8 5.5 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 MAD PF05557.13 KXS17291.1 - 0.016 13.6 3.6 0.024 13.0 3.6 1.2 1 0 0 1 1 1 0 Mitotic checkpoint protein Filament PF00038.21 KXS17291.1 - 0.017 14.8 2.7 0.022 14.3 2.7 1.1 1 0 0 1 1 1 0 Intermediate filament protein Baculo_PEP_C PF04513.12 KXS17291.1 - 0.02 14.9 5.0 0.033 14.2 5.0 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus CENP-F_leu_zip PF10473.9 KXS17291.1 - 0.022 14.8 5.9 0.05 13.6 5.7 1.7 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fez1 PF06818.15 KXS17291.1 - 0.024 15.1 1.2 0.036 14.5 1.2 1.3 1 0 0 1 1 1 0 Fez1 SH3_9 PF14604.6 KXS17291.1 - 0.025 14.5 0.0 0.049 13.5 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain EzrA PF06160.12 KXS17291.1 - 0.025 12.8 1.7 0.033 12.4 1.7 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA YabA PF06156.13 KXS17291.1 - 0.028 15.1 2.6 0.6 10.8 0.1 2.3 1 1 1 2 2 2 0 Initiation control protein YabA Shugoshin_N PF07558.11 KXS17291.1 - 0.034 14.0 4.3 1.1 9.1 0.2 3.0 2 1 1 3 3 3 0 Shugoshin N-terminal coiled-coil region Macoilin PF09726.9 KXS17291.1 - 0.035 12.7 3.1 0.049 12.2 3.1 1.2 1 0 0 1 1 1 0 Macoilin family DUF2353 PF09789.9 KXS17291.1 - 0.039 13.3 5.1 0.096 12.0 5.1 1.6 1 1 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) APG6_N PF17675.1 KXS17291.1 - 0.04 14.4 6.6 0.17 12.4 6.6 1.8 1 1 0 1 1 1 0 Apg6 coiled-coil region ZapB PF06005.12 KXS17291.1 - 0.04 14.3 7.4 1.4 9.4 0.2 3.1 1 1 2 3 3 3 0 Cell division protein ZapB IFT57 PF10498.9 KXS17291.1 - 0.046 12.7 0.5 0.062 12.3 0.5 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 K-box PF01486.17 KXS17291.1 - 0.049 13.8 4.6 1.2 9.4 1.4 2.2 1 1 1 2 2 2 0 K-box region THOC7 PF05615.13 KXS17291.1 - 0.054 13.8 4.4 0.075 13.3 3.8 1.4 1 1 0 1 1 1 0 Tho complex subunit 7 DUF724 PF05266.14 KXS17291.1 - 0.054 13.3 1.9 0.087 12.6 1.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) CALCOCO1 PF07888.11 KXS17291.1 - 0.056 12.3 7.7 0.077 11.8 7.7 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF4472 PF14739.6 KXS17291.1 - 0.064 14.0 5.3 0.077 13.7 3.3 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) DUF4686 PF15742.5 KXS17291.1 - 0.069 12.3 4.5 0.087 11.9 4.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4686) HAUS-augmin3 PF14932.6 KXS17291.1 - 0.074 12.6 1.8 0.098 12.2 1.8 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 PI3K_P85_iSH2 PF16454.5 KXS17291.1 - 0.083 12.5 1.4 0.13 11.9 1.4 1.3 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain HAP1_N PF04849.13 KXS17291.1 - 0.083 12.1 6.7 0.11 11.6 6.7 1.1 1 0 0 1 1 1 0 HAP1 N-terminal conserved region FUSC PF04632.12 KXS17291.1 - 0.089 11.3 5.1 0.12 10.8 5.1 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Bacillus_HBL PF05791.11 KXS17291.1 - 0.12 12.2 2.0 0.19 11.6 2.0 1.3 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) TMF_TATA_bd PF12325.8 KXS17291.1 - 0.13 12.5 7.2 0.21 11.8 0.8 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.8 KXS17291.1 - 0.13 12.3 6.4 0.14 12.2 0.2 2.3 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding USP8_interact PF08941.10 KXS17291.1 - 0.14 12.0 0.7 0.24 11.2 0.3 1.6 1 1 1 2 2 2 0 USP8 interacting Cnn_1N PF07989.11 KXS17291.1 - 0.14 12.3 1.1 0.38 10.9 0.1 2.0 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 Ax_dynein_light PF10211.9 KXS17291.1 - 0.17 11.8 2.2 0.41 10.6 2.2 1.6 1 1 0 1 1 1 0 Axonemal dynein light chain ATG16 PF08614.11 KXS17291.1 - 0.18 12.0 12.6 0.28 11.4 12.6 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) BRE1 PF08647.11 KXS17291.1 - 0.18 11.9 6.7 0.17 12.0 0.5 2.1 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase DUF1664 PF07889.12 KXS17291.1 - 0.21 11.6 0.9 0.35 10.9 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) HOOK PF05622.12 KXS17291.1 - 0.22 9.7 4.1 0.28 9.3 4.1 1.0 1 0 0 1 1 1 0 HOOK protein Leu_zip PF15294.6 KXS17291.1 - 0.23 10.9 4.2 0.33 10.4 4.2 1.1 1 0 0 1 1 1 0 Leucine zipper DUF812 PF05667.11 KXS17291.1 - 0.25 10.2 4.5 0.32 9.8 4.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) ADIP PF11559.8 KXS17291.1 - 0.25 11.4 10.7 0.065 13.3 4.2 2.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF3450 PF11932.8 KXS17291.1 - 0.28 10.5 5.5 0.42 9.9 5.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Seryl_tRNA_N PF02403.22 KXS17291.1 - 0.36 11.1 2.5 0.62 10.3 2.5 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Cep57_CLD_2 PF14197.6 KXS17291.1 - 0.37 10.9 6.7 0.3 11.2 3.8 2.2 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 DUF1640 PF07798.11 KXS17291.1 - 0.64 10.1 6.5 8.7 6.4 6.5 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) PRKG1_interact PF15898.5 KXS17291.1 - 0.76 10.7 5.8 2.2 9.2 5.5 1.9 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain Rootletin PF15035.6 KXS17291.1 - 0.84 9.6 7.7 1.4 8.9 7.6 1.4 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion UPF0242 PF06785.11 KXS17291.1 - 0.92 9.6 2.6 1.3 9.1 2.6 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Cluap1 PF10234.9 KXS17291.1 - 1.2 8.5 5.4 1.7 8.0 5.4 1.1 1 0 0 1 1 1 0 Clusterin-associated protein-1 Lectin_N PF03954.14 KXS17291.1 - 1.5 8.6 4.9 19 5.0 5.5 2.3 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain CENP-H PF05837.12 KXS17291.1 - 1.6 9.1 10.4 1.8 9.0 7.7 2.3 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Nup54 PF13874.6 KXS17291.1 - 2 8.5 8.2 3.8 7.6 8.2 1.4 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 TPR_MLP1_2 PF07926.12 KXS17291.1 - 2.9 7.9 11.3 19 5.4 11.2 2.1 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Nnf1 PF03980.14 KXS17291.1 - 3.6 8.0 8.8 12 6.3 4.7 2.3 1 1 1 2 2 2 0 Nnf1 CLZ PF16526.5 KXS17291.1 - 8.7 6.8 7.1 3.5 8.1 1.9 2.2 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels F-box-like PF12937.7 KXS17293.1 - 0.00036 20.4 0.4 0.00099 19.0 0.4 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXS17293.1 - 0.00071 19.4 0.3 0.0025 17.7 0.1 1.9 2 0 0 2 2 2 1 F-box domain SH3_9 PF14604.6 KXS17294.1 - 1.6e-07 31.1 0.0 2.2e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXS17294.1 - 3.2e-07 29.8 0.0 4.4e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KXS17294.1 - 0.0042 16.7 0.0 0.0067 16.1 0.0 1.4 1 1 0 1 1 1 1 Variant SH3 domain DUF1761 PF08570.10 KXS17294.1 - 0.0067 16.7 0.1 0.0085 16.3 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1761) SH3_9 PF14604.6 KXS17296.1 - 5.9e-06 26.0 0.0 1.3e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXS17296.1 - 9.9e-06 25.1 0.0 3.5e-05 23.3 0.0 2.0 2 0 0 2 2 1 1 SH3 domain KASH_CCD PF14662.6 KXS17296.1 - 4.3e-05 23.4 7.9 0.00077 19.3 6.8 2.2 2 0 0 2 2 2 1 Coiled-coil region of CCDC155 or KASH Cnn_1N PF07989.11 KXS17296.1 - 0.0017 18.4 5.4 0.89 9.8 3.7 3.1 2 1 0 2 2 2 1 Centrosomin N-terminal motif 1 GIT_CC PF16559.5 KXS17296.1 - 0.002 18.0 16.2 0.0087 15.9 2.1 3.8 2 1 2 4 4 4 2 GIT coiled-coil Rho guanine nucleotide exchange factor TSC22 PF01166.18 KXS17296.1 - 0.0022 18.3 4.2 0.51 10.7 0.3 3.5 1 1 2 3 3 3 1 TSC-22/dip/bun family bZIP_1 PF00170.21 KXS17296.1 - 0.0031 17.6 3.7 0.49 10.5 0.2 3.3 2 1 3 5 5 4 2 bZIP transcription factor Fez1 PF06818.15 KXS17296.1 - 0.016 15.7 1.5 0.016 15.7 1.5 1.6 2 0 0 2 2 1 0 Fez1 TMCO5 PF14992.6 KXS17296.1 - 0.019 14.6 3.6 3.1 7.3 5.1 2.2 1 1 1 2 2 2 0 TMCO5 family DivIC PF04977.15 KXS17296.1 - 0.02 14.7 11.9 2.1 8.2 1.0 3.9 2 1 2 4 4 4 0 Septum formation initiator DUF3584 PF12128.8 KXS17296.1 - 0.029 11.9 5.1 0.038 11.5 5.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) YabA PF06156.13 KXS17296.1 - 0.032 14.9 7.5 1.3 9.6 0.8 3.1 1 1 3 4 4 4 0 Initiation control protein YabA APG6_N PF17675.1 KXS17296.1 - 0.037 14.6 9.2 1.1 9.8 8.1 2.5 1 1 0 1 1 1 0 Apg6 coiled-coil region CALCOCO1 PF07888.11 KXS17296.1 - 0.067 12.1 4.2 0.094 11.6 4.2 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Atg14 PF10186.9 KXS17296.1 - 0.1 11.6 3.9 0.1 11.7 2.9 1.4 2 0 0 2 2 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Rootletin PF15035.6 KXS17296.1 - 0.18 11.8 8.5 0.33 11.0 8.5 1.5 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion UPF0449 PF15136.6 KXS17296.1 - 0.19 12.2 2.5 0.57 10.7 1.7 2.2 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 CCDC92 PF14916.6 KXS17296.1 - 0.21 11.4 3.8 19 5.1 0.0 3.2 1 1 2 3 3 3 0 Coiled-coil domain of unknown function Spc7 PF08317.11 KXS17296.1 - 0.23 10.3 8.4 0.3 9.9 7.5 1.5 2 0 0 2 2 2 0 Spc7 kinetochore protein ATG16 PF08614.11 KXS17296.1 - 0.24 11.6 11.8 0.42 10.8 11.8 1.4 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) TMF_DNA_bd PF12329.8 KXS17296.1 - 0.25 11.3 3.2 23 5.1 0.3 3.1 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding Tropomyosin PF00261.20 KXS17296.1 - 0.37 10.1 7.6 1.1 8.5 0.1 2.1 2 0 0 2 2 2 0 Tropomyosin T2SSF PF00482.23 KXS17296.1 - 0.43 10.5 1.8 5.5 7.0 0.2 2.8 1 1 2 3 3 3 0 Type II secretion system (T2SS), protein F SOGA PF11365.8 KXS17296.1 - 0.47 11.6 3.1 1.1 10.5 0.3 2.5 1 1 1 2 2 2 0 Protein SOGA ZapB PF06005.12 KXS17296.1 - 0.5 10.8 11.3 0.94 10.0 3.1 3.3 1 1 3 4 4 4 0 Cell division protein ZapB Shugoshin_N PF07558.11 KXS17296.1 - 0.59 10.0 6.6 5 7.1 0.5 3.5 3 1 0 4 4 3 0 Shugoshin N-terminal coiled-coil region Tropomyosin_1 PF12718.7 KXS17296.1 - 0.61 10.2 8.2 0.51 10.5 3.4 2.6 2 1 1 3 3 3 0 Tropomyosin like Csm1_N PF18504.1 KXS17296.1 - 1 9.7 7.8 2.4 8.5 0.6 3.2 2 1 1 3 3 3 0 Csm1 N-terminal domain DUF4763 PF15960.5 KXS17296.1 - 1.1 8.6 10.7 1.4 8.2 0.1 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4763) Jnk-SapK_ap_N PF09744.9 KXS17296.1 - 1.2 9.3 7.0 8.5 6.6 0.5 2.2 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 DUF5082 PF16888.5 KXS17296.1 - 1.3 9.3 7.0 8.1 6.7 6.7 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) DUF4472 PF14739.6 KXS17296.1 - 1.5 9.6 5.4 6.5 7.5 4.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) Uso1_p115_C PF04871.13 KXS17296.1 - 1.9 8.9 7.0 2.2 8.7 3.9 2.3 2 1 1 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region Golgin_A5 PF09787.9 KXS17296.1 - 2.4 7.6 7.4 0.91 8.9 4.7 1.5 2 0 0 2 2 2 0 Golgin subfamily A member 5 JIP_LZII PF16471.5 KXS17296.1 - 2.5 8.3 6.3 2.6 8.3 0.8 3.0 2 1 3 5 5 5 0 JNK-interacting protein leucine zipper II PRKG1_interact PF15898.5 KXS17296.1 - 3.3 8.7 7.6 4.4 8.3 5.1 2.4 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain Mod_r PF07200.13 KXS17296.1 - 3.3 7.8 9.6 4.1 7.5 8.3 1.8 2 0 0 2 2 1 0 Modifier of rudimentary (Mod(r)) protein CENP-F_leu_zip PF10473.9 KXS17296.1 - 3.4 7.7 7.5 2.7 8.0 5.7 1.8 2 0 0 2 2 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4618 PF15397.6 KXS17296.1 - 4.3 6.7 9.1 12 5.3 8.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) DUF3450 PF11932.8 KXS17296.1 - 5.8 6.1 12.2 1.4 8.1 7.6 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF3450) Fib_alpha PF08702.10 KXS17296.1 - 6 7.0 7.2 3.7 7.7 5.2 1.7 2 0 0 2 2 1 0 Fibrinogen alpha/beta chain family ERM PF00769.19 KXS17296.1 - 9.6 5.9 10.5 0.52 10.1 5.1 1.5 2 0 0 2 2 1 0 Ezrin/radixin/moesin family Ank_2 PF12796.7 KXS17297.1 - 0.00074 20.1 0.0 0.01 16.4 0.0 2.1 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXS17297.1 - 0.00096 19.4 0.0 0.016 15.7 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 KXS17297.1 - 0.016 15.8 0.0 10 6.9 0.0 2.3 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXS17297.1 - 0.028 14.7 0.0 5.6 7.4 0.0 2.3 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank PF00023.30 KXS17297.1 - 0.076 13.5 0.0 1.3 9.6 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeat HA2 PF04408.23 KXS17298.1 - 1.9e-17 63.5 0.0 1.9e-17 63.5 0.0 2.5 3 0 0 3 3 3 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KXS17298.1 - 2e-11 44.2 0.0 1.5e-10 41.4 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 KXS17298.1 - 1.2e-05 25.5 0.0 3.2e-05 24.2 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_23 PF13476.6 KXS17298.1 - 0.23 11.9 0.0 0.23 11.9 0.0 2.6 2 1 1 3 3 3 0 AAA domain F-box-like PF12937.7 KXS17302.1 - 0.00017 21.4 0.1 0.00029 20.6 0.1 1.3 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXS17302.1 - 0.069 13.0 0.1 0.14 12.0 0.1 1.4 1 0 0 1 1 1 0 F-box domain RNase_H PF00075.24 KXS17303.1 - 2.4e-24 86.2 0.1 5.4e-24 85.0 0.1 1.6 1 1 0 1 1 1 1 RNase H RVT_3 PF13456.6 KXS17303.1 - 2.5e-05 24.1 0.0 0.0083 15.9 0.0 2.2 2 0 0 2 2 2 2 Reverse transcriptase-like TolB_N PF04052.13 KXS17303.1 - 0.076 13.2 0.0 0.25 11.5 0.0 1.8 2 0 0 2 2 2 0 TolB amino-terminal domain TetR_C_12 PF16914.5 KXS17303.1 - 0.094 12.8 1.0 0.17 12.0 1.0 1.4 1 0 0 1 1 1 0 Bacterial transcriptional repressor C-terminal RRM_1 PF00076.22 KXS17305.1 - 9.4e-15 54.2 0.0 1.3e-14 53.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.23 KXS17305.1 - 1.3e-11 44.0 12.7 2e-06 27.6 1.7 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_5 PF14787.6 KXS17305.1 - 4.8e-06 26.2 11.9 0.00031 20.4 0.9 2.5 2 0 0 2 2 2 2 GAG-polyprotein viral zinc-finger RRM_5 PF13893.6 KXS17305.1 - 0.0038 16.8 0.0 0.0047 16.5 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC_2 PF13696.6 KXS17305.1 - 0.0043 16.8 2.5 0.0043 16.8 2.5 2.6 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_4 PF14392.6 KXS17305.1 - 0.0054 16.4 7.8 0.055 13.2 0.6 2.3 2 0 0 2 2 2 2 Zinc knuckle CLIP1_ZNF PF16641.5 KXS17305.1 - 0.096 12.6 1.2 0.17 11.8 1.2 1.5 1 0 0 1 1 1 0 CLIP1 zinc knuckle zf-CCHC_3 PF13917.6 KXS17305.1 - 0.25 11.4 6.7 2.4 8.2 0.8 2.3 1 1 1 2 2 2 0 Zinc knuckle ABM PF03992.16 KXS17306.1 - 9.1e-27 93.0 0.0 4e-14 52.5 0.0 2.1 2 0 0 2 2 2 2 Antibiotic biosynthesis monooxygenase HgmA PF04209.13 KXS17307.1 - 1.2e-191 637.1 0.1 2e-191 636.3 0.1 1.3 1 1 0 1 1 1 1 homogentisate 1,2-dioxygenase Tom7 PF08038.12 KXS17308.1 - 1.1e-16 60.2 0.1 1.2e-16 60.1 0.1 1.0 1 0 0 1 1 1 1 TOM7 family zf-UBP PF02148.19 KXS17309.1 - 2.6e-16 59.7 0.0 9.2e-16 57.9 0.0 1.9 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein UCH PF00443.29 KXS17309.1 - 7.7e-14 51.8 0.0 7.7e-14 51.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KXS17309.1 - 0.0032 17.1 0.0 0.0071 16.0 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Mito_fiss_reg PF05308.11 KXS17309.1 - 2.5 8.1 4.8 9.8 6.2 0.8 2.4 2 0 0 2 2 2 0 Mitochondrial fission regulator DUF3967 PF13152.6 KXS17310.1 - 0.046 13.5 0.0 0.14 12.0 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3967) adh_short PF00106.25 KXS17311.1 - 6.5e-32 110.6 0.0 8.4e-32 110.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXS17311.1 - 4.5e-27 95.1 0.0 6.8e-27 94.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXS17311.1 - 5e-12 46.1 0.0 7.8e-12 45.5 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXS17311.1 - 9.5e-06 25.2 0.0 1.6e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXS17311.1 - 2e-05 24.2 0.0 3.3e-05 23.5 0.0 1.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KXS17311.1 - 0.00075 18.7 0.0 0.0012 18.0 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 KXS17311.1 - 0.0015 18.4 0.0 0.0025 17.7 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding F420_oxidored PF03807.17 KXS17311.1 - 0.025 15.2 0.0 0.059 14.0 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Mur_ligase PF01225.25 KXS17311.1 - 0.14 12.5 0.0 0.34 11.3 0.0 1.5 1 0 0 1 1 1 0 Mur ligase family, catalytic domain Ank_2 PF12796.7 KXS17312.1 - 1.8e-23 82.9 0.0 3.1e-14 53.3 0.0 3.4 2 1 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXS17312.1 - 5.2e-17 60.2 2.0 0.0017 18.7 0.0 6.4 6 0 0 6 6 6 3 Ankyrin repeat Ank PF00023.30 KXS17312.1 - 1.1e-12 47.7 9.4 0.0045 17.4 0.1 5.6 4 2 1 5 5 5 3 Ankyrin repeat Ank_4 PF13637.6 KXS17312.1 - 2.3e-10 40.8 2.2 4e-07 30.5 0.1 4.5 2 2 3 5 5 5 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXS17312.1 - 3.9e-10 39.8 4.9 0.067 13.5 0.1 5.6 3 2 3 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXS17314.1 - 0.00081 19.7 0.0 0.0023 18.3 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeat Ank_2 PF12796.7 KXS17314.1 - 0.0012 19.4 0.0 0.0038 17.8 0.0 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KXS17314.1 - 0.002 18.5 0.0 0.043 14.3 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeat TPR_2 PF07719.17 KXS17315.1 - 7.8e-06 25.6 0.0 12 6.3 0.0 4.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 KXS17315.1 - 0.00018 21.7 0.3 6.9 7.0 0.0 4.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KXS17315.1 - 0.0061 16.3 0.0 33 4.5 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 KXS17315.1 - 0.077 13.2 0.0 22 5.6 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 KXS17315.1 - 0.18 12.5 14.9 18 6.1 0.1 6.4 7 0 0 7 7 7 0 Tetratricopeptide repeat PG_binding_3 PF09374.10 KXS17315.1 - 0.19 12.0 0.4 8.6 6.7 0.0 2.5 2 0 0 2 2 2 0 Predicted Peptidoglycan domain TPR_14 PF13428.6 KXS17315.1 - 5.6 8.1 9.1 1.4e+02 3.7 0.0 5.2 4 0 0 4 4 4 0 Tetratricopeptide repeat RPAP3_C PF13877.6 KXS17317.1 - 1.1e-16 61.1 0.0 2.4e-16 60.0 0.0 1.6 1 0 0 1 1 1 1 Potential Monad-binding region of RPAP3 TPR_1 PF00515.28 KXS17317.1 - 5e-08 32.4 0.0 0.11 12.3 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KXS17317.1 - 7.4e-08 31.9 0.1 0.037 14.1 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_9 PF13371.6 KXS17317.1 - 1e-05 25.5 0.2 2.6e-05 24.3 0.2 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.6 KXS17317.1 - 0.0015 18.2 0.0 0.023 14.4 0.0 2.4 2 0 0 2 2 2 1 TPR repeat TPR_19 PF14559.6 KXS17317.1 - 0.12 12.9 0.0 0.29 11.6 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat BTB PF00651.31 KXS17318.1 - 0.015 15.6 0.0 0.03 14.5 0.0 1.6 2 0 0 2 2 2 0 BTB/POZ domain Ephrin_rec_like PF07699.13 KXS17319.1 - 2.7e-31 107.1 67.5 2.1e-06 27.4 4.7 8.5 1 1 6 8 8 8 8 Putative ephrin-receptor like NCD3G PF07562.14 KXS17319.1 - 1.9e-10 40.5 43.9 0.064 13.2 4.6 6.5 2 1 4 7 7 7 7 Nine Cysteines Domain of family 3 GPCR TNFR_c6 PF00020.18 KXS17319.1 - 7e-08 32.7 43.7 0.058 13.8 1.1 8.4 2 2 5 8 8 8 8 TNFR/NGFR cysteine-rich region GSIII_N PF12437.8 KXS17319.1 - 0.032 13.9 0.2 0.082 12.6 0.2 1.6 1 0 0 1 1 1 0 Glutamine synthetase type III N terminal DUF2318 PF10080.9 KXS17319.1 - 0.053 13.7 29.3 1.1 9.4 0.7 4.9 1 1 4 5 5 5 0 Predicted membrane protein (DUF2318) VSP PF03302.13 KXS17319.1 - 0.064 12.1 46.8 8.8 5.1 16.1 3.5 1 1 2 3 3 3 0 Giardia variant-specific surface protein AT_hook PF02178.19 KXS17320.1 - 0.025 14.4 3.6 0.063 13.2 3.6 1.7 1 0 0 1 1 1 0 AT hook motif TMEM247 PF15444.6 KXS17320.1 - 0.25 11.3 0.2 0.51 10.3 0.2 1.5 2 0 0 2 2 2 0 Transmembrane protein 247 HMG_box PF00505.19 KXS17321.1 - 5.6e-12 45.9 35.8 0.00067 20.0 5.2 5.8 6 0 0 6 6 6 5 HMG (high mobility group) box HMG_box_2 PF09011.10 KXS17321.1 - 7e-05 23.4 19.3 0.29 11.8 3.6 4.5 3 2 1 4 4 4 3 HMG-box domain PS_Dcarbxylase PF02666.15 KXS17322.1 - 1.8e-22 79.9 0.0 2.5e-22 79.4 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase UCR_14kD PF02271.16 KXS17323.1 - 3e-32 110.5 0.3 3.5e-32 110.3 0.3 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit DUF2357 PF09823.9 KXS17323.1 - 0.053 12.8 0.1 0.056 12.7 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2357) ODC_AZ PF02100.17 KXS17324.1 - 1.8e-12 47.3 0.0 2.8e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme BRO1 PF03097.18 KXS17325.1 - 7.1e-60 202.8 0.0 1.7e-59 201.6 0.0 1.6 1 0 0 1 1 1 1 BRO1-like domain KIAA1430 PF13879.6 KXS17325.1 - 0.074 13.8 22.0 0.29 11.9 11.7 3.3 2 1 1 3 3 3 0 KIAA1430 homologue DUF4922 PF16269.5 KXS17325.1 - 0.9 9.3 2.8 1 9.1 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4922) DUF4763 PF15960.5 KXS17325.1 - 4.6 6.5 20.4 2.8 7.2 4.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4763) DUF948 PF06103.11 KXS17325.1 - 4.8 7.5 13.4 2.3 8.5 2.0 3.8 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) Spc7 PF08317.11 KXS17325.1 - 4.9 5.9 27.9 3.2 6.6 11.8 2.8 2 0 0 2 2 2 0 Spc7 kinetochore protein NPV_P10 PF05531.12 KXS17325.1 - 5.6 7.5 10.2 27 5.3 0.5 4.5 3 1 2 5 5 5 0 Nucleopolyhedrovirus P10 protein Mannosyl_trans2 PF04188.13 KXS17326.1 - 3e-47 162.0 13.4 3e-47 162.0 13.4 1.9 1 1 1 2 2 2 1 Mannosyltransferase (PIG-V) AAA PF00004.29 KXS17327.1 - 0.00012 22.5 0.0 0.00051 20.5 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) IQ PF00612.27 KXS17327.1 - 3.7 7.6 7.1 1.9 8.5 3.6 2.4 2 0 0 2 2 2 0 IQ calmodulin-binding motif PAD PF03068.15 KXS17329.1 - 1e-99 334.2 0.0 1.3e-99 333.9 0.0 1.1 1 0 0 1 1 1 1 Protein-arginine deiminase (PAD) zf-MYND PF01753.18 KXS17330.1 - 6.1e-14 51.8 32.0 5.1e-07 29.7 12.7 2.5 2 0 0 2 2 2 2 MYND finger zf-C6H2 PF15801.5 KXS17330.1 - 8.6 6.8 30.2 0.34 11.2 11.1 2.6 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding MFS_1 PF07690.16 KXS17332.1 - 0.0015 17.5 0.6 0.0018 17.3 0.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Thioredox_DsbH PF03190.15 KXS17333.1 - 2.1e-73 245.6 0.1 3.6e-73 244.9 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.6 KXS17333.1 - 6.3e-08 32.7 0.0 1.3e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like MFS_1 PF07690.16 KXS17334.1 - 6.6e-33 114.1 30.2 6.6e-33 114.1 30.2 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Nodulin-like PF06813.13 KXS17334.1 - 0.0081 15.7 10.8 0.084 12.3 10.8 2.4 1 1 0 1 1 1 1 Nodulin-like Pkinase PF00069.25 KXS17336.1 - 3.4e-32 111.8 0.0 5.2e-30 104.7 0.0 3.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS17336.1 - 4.8e-09 35.9 0.0 0.00014 21.2 0.0 3.1 2 1 0 3 3 3 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXS17336.1 - 0.16 10.7 0.0 0.4 9.4 0.0 1.6 2 0 0 2 2 2 0 Fungal protein kinase Kinase-like PF14531.6 KXS17336.1 - 0.16 11.2 0.0 16 4.7 0.0 2.2 2 0 0 2 2 2 0 Kinase-like Kdo PF06293.14 KXS17336.1 - 0.17 11.2 0.0 0.4 10.0 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Arf PF00025.21 KXS17337.1 - 3.1e-61 205.9 0.0 3.5e-61 205.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KXS17337.1 - 5.4e-13 49.2 0.0 7.4e-13 48.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 KXS17337.1 - 2e-11 43.7 0.2 1.5e-06 27.6 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 KXS17337.1 - 4.3e-10 39.3 0.0 5.4e-10 39.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.22 KXS17337.1 - 4.4e-09 36.1 0.0 5e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 KXS17337.1 - 6.6e-09 35.9 0.0 9e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 KXS17337.1 - 7.7e-09 35.2 0.0 1.1e-08 34.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 KXS17337.1 - 0.00025 20.7 0.1 0.036 13.6 0.0 2.1 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain cobW PF02492.19 KXS17337.1 - 0.062 12.9 0.0 1.5 8.4 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain CdhD PF03599.16 KXS17337.1 - 0.088 11.5 0.0 0.1 11.3 0.0 1.1 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase delta subunit TniB PF05621.11 KXS17337.1 - 0.12 11.8 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein DUF463 PF04317.12 KXS17337.1 - 0.17 10.8 0.1 2.5 6.9 0.0 2.0 2 0 0 2 2 2 0 YcjX-like family, DUF463 FeoB_N PF02421.18 KXS17337.1 - 0.19 11.3 0.0 1.1 8.7 0.0 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B Dynamin_N PF00350.23 KXS17337.1 - 0.23 11.5 0.0 2.2 8.3 0.0 1.9 1 1 0 2 2 2 0 Dynamin family DEAD PF00270.29 KXS17338.1 - 9.6e-51 172.0 0.0 1.4e-50 171.5 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXS17338.1 - 3.3e-30 104.7 0.0 2.6e-29 101.8 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXS17338.1 - 0.00024 21.1 0.0 0.0004 20.4 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 KXS17338.1 - 0.015 14.1 0.0 0.28 9.9 0.0 2.3 2 1 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 CMS1 PF14617.6 KXS17338.1 - 0.17 11.2 0.0 0.29 10.4 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit U-box PF04564.15 KXS17339.1 - 3.5e-18 65.6 0.8 3.8e-18 65.4 0.1 1.4 2 0 0 2 2 2 1 U-box domain zf-Nse PF11789.8 KXS17339.1 - 0.003 17.4 0.1 0.0083 15.9 0.1 1.7 1 1 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-NOSIP PF15906.5 KXS17339.1 - 0.045 13.9 0.0 0.065 13.4 0.0 1.2 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein zf-RING_UBOX PF13445.6 KXS17339.1 - 0.064 13.3 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 RING-type zinc-finger Rtf2 PF04641.12 KXS17339.1 - 0.19 11.1 0.0 0.26 10.6 0.0 1.3 1 1 0 1 1 1 0 Rtf2 RING-finger DnaJ PF00226.31 KXS17340.1 - 7.2e-12 45.3 0.7 1.9e-11 43.9 0.7 1.7 1 0 0 1 1 1 1 DnaJ domain zf-CCCH_4 PF18044.1 KXS17340.1 - 8.6e-05 22.2 3.8 0.0002 21.1 3.8 1.6 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH PF00642.24 KXS17340.1 - 0.00054 19.8 1.2 0.00054 19.8 1.2 2.2 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KXS17340.1 - 0.0053 16.8 12.2 0.029 14.4 10.2 2.4 2 0 0 2 2 2 1 Zinc finger domain zf-CCCH_3 PF15663.5 KXS17340.1 - 0.061 13.5 1.1 0.15 12.3 1.1 1.6 1 0 0 1 1 1 0 Zinc-finger containing family Torus PF16131.5 KXS17340.1 - 0.29 11.8 5.6 0.097 13.4 1.0 2.6 1 1 1 2 2 2 0 Torus domain DUF1964 PF09244.10 KXS17340.1 - 0.33 11.4 1.3 0.84 10.1 0.0 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1964) zf-CCCH_2 PF14608.6 KXS17340.1 - 0.34 11.4 3.0 0.67 10.5 3.0 1.5 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger DUF4419 PF14388.6 KXS17341.1 - 1.2e-06 28.2 0.0 1.5e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) DUF4419 PF14388.6 KXS17342.1 - 1.8e-46 159.0 0.3 1.9e-46 158.8 0.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) MutS_III PF05192.18 KXS17342.1 - 0.083 13.1 0.0 0.088 13.0 0.0 1.1 1 0 0 1 1 1 0 MutS domain III Syntaxin-6_N PF09177.11 KXS17344.1 - 6.2e-24 84.4 1.7 5.5e-23 81.4 0.2 2.2 2 0 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.19 KXS17344.1 - 0.0014 18.6 0.3 0.0042 17.1 0.3 1.9 1 0 0 1 1 1 1 SNARE domain Use1 PF09753.9 KXS17344.1 - 0.0061 16.3 0.6 0.0085 15.8 0.4 1.3 1 1 0 1 1 1 1 Membrane fusion protein Use1 Cob_adeno_trans PF01923.18 KXS17344.1 - 0.041 14.0 0.3 0.45 10.7 0.0 2.1 2 0 0 2 2 2 0 Cobalamin adenosyltransferase Insulin_TMD PF17870.1 KXS17344.1 - 0.06 13.4 0.6 0.1 12.7 0.6 1.3 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Baculo_PEP_C PF04513.12 KXS17344.1 - 0.16 12.0 4.4 6.6 6.8 0.1 2.4 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus PspA_IM30 PF04012.12 KXS17344.1 - 0.17 11.5 7.8 3.1 7.3 0.3 2.2 2 0 0 2 2 2 0 PspA/IM30 family DUF745 PF05335.13 KXS17344.1 - 0.17 11.6 4.4 0.87 9.3 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Spc7 PF08317.11 KXS17344.1 - 0.35 9.7 4.8 4.5 6.1 0.7 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein OAD_gamma PF04277.13 KXS17344.1 - 0.42 11.2 6.6 1.1 9.9 6.6 1.8 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain GAS PF13851.6 KXS17344.1 - 0.63 9.4 3.6 0.8 9.0 0.1 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF3040 PF11239.8 KXS17344.1 - 0.72 10.2 7.6 0.56 10.5 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3040) cobW PF02492.19 KXS17345.1 - 1.5e-53 181.0 1.2 2.1e-53 180.5 1.2 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 KXS17345.1 - 5.2e-15 55.1 0.0 9.2e-15 54.3 0.0 1.4 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain RsgA_GTPase PF03193.16 KXS17345.1 - 0.01 15.7 0.8 1.1 9.1 0.1 2.3 2 0 0 2 2 2 0 RsgA GTPase MobB PF03205.14 KXS17345.1 - 0.18 11.7 0.3 0.59 10.0 0.3 1.9 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B GTP_EFTU PF00009.27 KXS17345.1 - 0.18 11.3 2.6 1.9 8.0 2.7 2.0 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain Complex1_LYR PF05347.15 KXS17346.1 - 3.5e-07 30.2 0.3 5.5e-07 29.5 0.3 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) PAS_9 PF13426.7 KXS17347.1 - 3.8e-24 84.9 0.0 3.8e-14 52.8 0.1 3.3 3 0 0 3 3 3 3 PAS domain PAS_3 PF08447.12 KXS17347.1 - 5.8e-14 52.1 0.0 1.6e-10 41.2 0.0 3.2 3 0 0 3 3 3 2 PAS fold PAS PF00989.25 KXS17347.1 - 1.1e-09 38.2 0.0 0.0021 18.0 0.0 3.5 3 0 0 3 3 3 3 PAS fold PAS_4 PF08448.10 KXS17347.1 - 1.9e-08 34.5 0.0 0.035 14.3 0.0 3.7 3 0 0 3 3 3 2 PAS fold PAS_11 PF14598.6 KXS17347.1 - 0.0027 17.8 0.0 0.0057 16.8 0.0 1.5 1 0 0 1 1 1 1 PAS domain PAS_8 PF13188.7 KXS17347.1 - 0.029 14.4 0.0 2.7 8.1 0.0 2.7 2 0 0 2 2 2 0 PAS domain TIP39 PF14980.6 KXS17348.1 - 0.07 13.0 0.1 0.15 11.9 0.1 1.5 1 0 0 1 1 1 0 TIP39 peptide AMP-binding PF00501.28 KXS17349.1 - 2.6e-90 303.1 0.0 3.5e-90 302.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme SMC_N PF02463.19 KXS17350.1 - 6.7e-22 78.0 0.0 1.7e-21 76.7 0.0 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KXS17350.1 - 1.2e-13 52.1 20.5 1.2e-13 52.1 20.5 5.3 2 2 0 2 2 1 1 AAA domain AAA_15 PF13175.6 KXS17350.1 - 9.7e-07 28.8 0.5 9.7e-07 28.8 0.5 2.7 2 1 0 2 2 1 1 AAA ATPase domain AAA_29 PF13555.6 KXS17350.1 - 9.9e-06 25.2 0.0 2e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain TPR_MLP1_2 PF07926.12 KXS17350.1 - 0.0029 17.7 13.6 0.0029 17.7 13.6 6.8 4 1 1 6 6 4 1 TPR/MLP1/MLP2-like protein PEARLI-4 PF05278.12 KXS17350.1 - 0.0069 16.0 0.7 0.0069 16.0 0.7 6.3 5 2 1 7 7 7 1 Arabidopsis phospholipase-like protein (PEARLI 4) AAA_21 PF13304.6 KXS17350.1 - 0.0094 15.8 1.1 0.023 14.5 0.1 2.2 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 KXS17350.1 - 0.063 13.7 0.1 1.5 9.2 0.0 3.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) SMC_hinge PF06470.13 KXS17350.1 - 0.066 13.5 0.0 0.2 11.9 0.0 1.9 1 0 0 1 1 1 0 SMC proteins Flexible Hinge Domain Spc7 PF08317.11 KXS17350.1 - 0.19 10.6 75.5 0.058 12.3 8.4 6.0 4 1 2 6 6 6 0 Spc7 kinetochore protein NPV_P10 PF05531.12 KXS17350.1 - 0.64 10.5 7.3 3.6 8.1 0.5 4.7 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF5595 PF18077.1 KXS17350.1 - 2.8 8.1 10.9 8.2 6.6 1.7 4.7 3 1 0 3 3 3 0 Domain of unknown function (DUF5595) Lipase_GDSL_2 PF13472.6 KXS17352.1 - 6.8e-13 49.4 0.0 8.2e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KXS17352.1 - 0.0017 18.3 0.0 0.0024 17.9 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase BTB PF00651.31 KXS17353.1 - 1.3e-07 31.8 0.0 2.9e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain RSN1_7TM PF02714.15 KXS17354.1 - 3.7e-72 242.9 21.8 5.3e-72 242.4 21.8 1.2 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_ext PF12621.8 KXS17354.1 - 1.4e-06 28.4 0.0 3.3e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter Anoctamin PF04547.12 KXS17354.1 - 0.00056 18.9 0.4 0.00056 18.9 0.4 1.6 2 0 0 2 2 2 1 Calcium-activated chloride channel NIF PF03031.18 KXS17356.1 - 6.4e-27 94.2 0.0 3.1e-25 88.8 0.0 2.6 3 0 0 3 3 3 1 NLI interacting factor-like phosphatase BRCT PF00533.26 KXS17356.1 - 0.00097 19.5 0.0 0.0031 17.9 0.0 1.8 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Biotin_lipoyl_2 PF13533.6 KXS17356.1 - 0.03 14.2 0.0 0.094 12.6 0.0 1.8 2 0 0 2 2 2 0 Biotin-lipoyl like MFS_1 PF07690.16 KXS17358.1 - 2e-27 96.1 20.3 2.8e-27 95.6 20.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Tox-HNH-HHH PF15637.6 KXS17358.1 - 0.12 12.5 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif MFS_1 PF07690.16 KXS17359.1 - 4.4e-25 88.4 36.1 4.4e-25 88.4 36.1 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Ank_2 PF12796.7 KXS17360.1 - 2.5e-25 88.9 0.1 2.3e-07 31.3 0.1 3.2 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXS17360.1 - 2.7e-21 75.6 1.1 1.6e-06 28.6 0.1 6.2 4 2 2 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 KXS17360.1 - 1.2e-15 57.1 6.9 0.0014 18.9 0.2 6.0 6 0 0 6 6 6 4 Ankyrin repeat Ank_3 PF13606.6 KXS17360.1 - 1.3e-12 46.7 2.8 0.041 14.4 0.0 6.2 7 0 0 7 7 7 3 Ankyrin repeat Ank_5 PF13857.6 KXS17360.1 - 7.8e-12 45.2 4.5 6.2e-07 29.6 0.1 4.1 3 1 1 4 4 4 3 Ankyrin repeats (many copies) DDE_Tnp_Tn3 PF01526.17 KXS17360.1 - 0.013 14.3 0.1 0.028 13.2 0.0 1.5 2 0 0 2 2 2 0 Tn3 transposase DDE domain Yip1 PF04893.17 KXS17361.1 - 4.3e-17 62.4 12.8 6.8e-17 61.7 12.8 1.4 1 0 0 1 1 1 1 Yip1 domain Tocopherol_cycl PF14249.6 KXS17362.1 - 8.5e-11 41.6 2.0 1.3e-10 41.0 2.0 1.3 1 0 0 1 1 1 1 Tocopherol cyclase DapB_N PF01113.20 KXS17362.1 - 0.14 12.2 0.0 0.29 11.3 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus WW PF00397.26 KXS17364.1 - 0.024 14.7 9.2 0.093 12.8 9.2 2.0 1 1 0 1 1 1 0 WW domain DUF2076 PF09849.9 KXS17364.1 - 0.34 10.9 3.2 0.41 10.7 3.2 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) ZZ PF00569.17 KXS17365.1 - 1.3e-09 37.7 4.5 1.9e-09 37.2 4.5 1.2 1 0 0 1 1 1 1 Zinc finger, ZZ type C1_2 PF03107.16 KXS17365.1 - 0.01 16.2 1.8 0.016 15.5 1.8 1.3 1 0 0 1 1 1 0 C1 domain Tnp_zf-ribbon_2 PF13842.6 KXS17365.1 - 0.2 12.5 5.0 0.33 11.8 5.0 1.3 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon DUF3040 PF11239.8 KXS17365.1 - 0.25 11.6 1.2 0.5 10.7 1.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) Pex14_N PF04695.13 KXS17366.1 - 1.5 9.5 9.2 1.7 9.3 9.2 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region YlzJ PF14035.6 KXS17368.1 - 0.11 12.7 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 YlzJ-like protein Glyco_H_20C_C PF18088.1 KXS17369.1 - 4.3e-37 127.9 0.0 6.8e-37 127.2 0.0 1.3 1 0 0 1 1 1 1 Glycoside Hydrolase 20C C-terminal domain Glyco_hydro_20 PF00728.22 KXS17369.1 - 2.2e-06 27.3 0.0 9.2e-06 25.3 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain UPRTase PF14681.6 KXS17370.1 - 1e-78 263.5 0.0 1.2e-78 263.3 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 KXS17370.1 - 0.00024 20.6 0.0 0.00037 20.1 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain DTW PF03942.15 KXS17371.1 - 2.3e-23 82.9 0.0 3.6e-23 82.3 0.0 1.2 1 0 0 1 1 1 1 DTW domain UQ_con PF00179.26 KXS17372.1 - 1.2e-38 131.9 0.0 1.6e-38 131.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DSBA PF01323.20 KXS17373.1 - 3.1e-12 46.7 0.0 3.5e-12 46.5 0.0 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain OrfB_Zn_ribbon PF07282.11 KXS17374.1 - 9.8e-11 41.4 0.3 2.1e-10 40.3 0.3 1.5 1 0 0 1 1 1 1 Putative transposase DNA-binding domain Katanin_con80 PF13925.6 KXS17376.1 - 0.2 11.7 1.9 0.27 11.3 1.2 1.6 2 0 0 2 2 2 0 con80 domain of Katanin HTH_23 PF13384.6 KXS17377.1 - 9.3e-07 28.5 0.9 0.059 13.2 0.1 3.4 3 0 0 3 3 3 2 Homeodomain-like domain HTH_28 PF13518.6 KXS17377.1 - 8.2e-06 25.9 0.4 0.29 11.3 0.0 3.3 3 0 0 3 3 3 2 Helix-turn-helix domain HTH_29 PF13551.6 KXS17377.1 - 0.00021 21.3 0.2 0.076 13.0 0.0 3.1 3 0 0 3 3 3 1 Winged helix-turn helix HTH_33 PF13592.6 KXS17377.1 - 0.0029 17.2 0.0 0.093 12.4 0.0 2.9 3 0 0 3 3 3 1 Winged helix-turn helix YdaS_antitoxin PF15943.5 KXS17377.1 - 0.0034 17.2 0.1 16 5.5 0.0 3.7 3 1 1 4 4 4 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_Tnp_IS630 PF01710.16 KXS17377.1 - 0.009 16.0 0.0 0.026 14.6 0.0 1.8 1 1 0 1 1 1 1 Transposase HTH_17 PF12728.7 KXS17377.1 - 0.015 15.4 0.0 11 6.3 0.0 3.1 1 1 1 2 2 2 0 Helix-turn-helix domain HTH_3 PF01381.22 KXS17377.1 - 0.036 14.1 0.0 11 6.2 0.0 3.2 3 0 0 3 3 3 0 Helix-turn-helix HTH_Tnp_ISL3 PF13542.6 KXS17377.1 - 0.036 13.5 0.2 0.53 9.8 0.0 2.8 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 Arg_repressor PF01316.21 KXS17377.1 - 0.043 13.6 0.2 0.098 12.4 0.2 1.6 1 0 0 1 1 1 0 Arginine repressor, DNA binding domain HTH_32 PF13565.6 KXS17377.1 - 0.09 13.4 0.1 0.76 10.4 0.1 2.2 1 1 1 2 2 2 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KXS17377.1 - 0.11 12.7 0.3 0.74 10.1 0.0 2.2 2 0 0 2 2 2 0 Transposase DDE_3 PF13358.6 KXS17378.1 - 4.2e-15 55.8 0.0 4.7e-08 32.9 0.0 3.0 3 0 0 3 3 3 2 DDE superfamily endonuclease HTH_33 PF13592.6 KXS17378.1 - 0.00051 19.6 0.1 0.016 14.9 0.0 2.8 2 0 0 2 2 2 1 Winged helix-turn helix HTH_32 PF13565.6 KXS17378.1 - 0.0014 19.2 0.3 0.0014 19.2 0.3 3.0 3 1 1 4 4 4 1 Homeodomain-like domain HTH_Tnp_IS630 PF01710.16 KXS17378.1 - 0.073 13.1 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Transposase HTH_23 PF13384.6 KXS17378.1 - 0.69 9.8 4.2 15 5.5 0.0 3.7 3 0 0 3 3 3 0 Homeodomain-like domain MerR PF00376.23 KXS17379.1 - 2.9e-05 23.7 0.0 4.7e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 MerR family regulatory protein HTH_28 PF13518.6 KXS17379.1 - 3.9e-05 23.7 0.1 0.0002 21.4 0.1 2.2 2 1 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KXS17379.1 - 4e-05 23.3 0.0 0.00012 21.8 0.0 1.7 2 0 0 2 2 2 1 Homeodomain-like domain HTH_32 PF13565.6 KXS17379.1 - 8.9e-05 23.0 0.7 0.15 12.7 0.0 2.1 2 0 0 2 2 2 2 Homeodomain-like domain HTH_11 PF08279.12 KXS17379.1 - 0.00031 20.6 0.0 0.00052 19.9 0.0 1.3 1 0 0 1 1 1 1 HTH domain MerR_1 PF13411.6 KXS17379.1 - 0.0006 19.8 0.1 0.0023 18.0 0.1 1.9 2 1 1 3 3 2 1 MerR HTH family regulatory protein Terminase_5 PF06056.12 KXS17379.1 - 0.0014 18.5 0.0 0.0042 16.9 0.0 1.7 2 0 0 2 2 2 1 Putative ATPase subunit of terminase (gpP-like) HTH_7 PF02796.15 KXS17379.1 - 0.0024 17.9 0.0 0.075 13.1 0.0 2.4 3 0 0 3 3 2 1 Helix-turn-helix domain of resolvase HTH_29 PF13551.6 KXS17379.1 - 0.0051 16.8 0.0 0.013 15.5 0.0 1.7 1 0 0 1 1 1 1 Winged helix-turn helix HTH_20 PF12840.7 KXS17379.1 - 0.0078 16.2 0.1 0.16 12.0 0.0 2.4 2 1 0 2 2 2 1 Helix-turn-helix domain HTH_3 PF01381.22 KXS17379.1 - 0.011 15.8 0.0 0.025 14.6 0.0 1.6 2 0 0 2 2 2 0 Helix-turn-helix HTH_35 PF13693.6 KXS17379.1 - 0.015 15.3 0.0 0.029 14.4 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_17 PF12728.7 KXS17379.1 - 0.02 15.1 0.0 0.031 14.4 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Tnp_1_2 PF13022.6 KXS17379.1 - 0.023 14.9 0.0 0.057 13.6 0.0 1.6 2 0 0 2 2 2 0 Helix-turn-helix of insertion element transposase HTH_40 PF14493.6 KXS17379.1 - 0.025 15.0 0.0 0.045 14.2 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain CENP-B_N PF04218.13 KXS17379.1 - 0.033 13.8 0.0 0.061 13.0 0.0 1.4 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain HTH_38 PF13936.6 KXS17379.1 - 0.039 13.7 0.0 0.07 12.9 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain LysM PF01476.20 KXS17379.1 - 0.09 12.9 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 LysM domain DUF433 PF04255.14 KXS17379.1 - 0.098 12.5 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF433) HTH_26 PF13443.6 KXS17379.1 - 0.14 12.7 0.0 0.24 11.8 0.0 1.4 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain Sigma70_r4 PF04545.16 KXS17379.1 - 0.15 11.6 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 Glycos_trans_3N PF02885.17 KXS17379.1 - 0.19 11.6 0.0 0.35 10.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family, helical bundle domain DSBA PF01323.20 KXS17380.1 - 0.0002 21.2 0.0 0.00021 21.2 0.0 1.2 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Ribophorin_I PF04597.14 KXS17382.1 - 2.9e-99 333.2 0.0 3.9e-99 332.8 0.0 1.2 1 0 0 1 1 1 1 Ribophorin I DUF948 PF06103.11 KXS17382.1 - 0.0031 17.7 1.0 0.0075 16.5 0.1 2.1 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF948) DUF802 PF05650.11 KXS17382.1 - 0.1 13.1 3.8 0.33 11.5 0.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF802) MFS_1 PF07690.16 KXS17384.1 - 2e-23 82.9 31.9 2e-23 82.9 31.9 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF2070 PF09843.9 KXS17384.1 - 0.21 9.8 4.1 0.34 9.1 4.1 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) TMA7 PF09072.10 KXS17385.1 - 3e-21 76.0 19.5 3.4e-21 75.9 19.5 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 zf-C2HC_2 PF13913.6 KXS17386.1 - 3.3e-09 36.4 15.6 1.2e-05 25.1 0.2 3.3 3 0 0 3 3 3 2 zinc-finger of a C2HC-type zinc_ribbon_15 PF17032.5 KXS17386.1 - 1.3e-05 25.9 6.2 0.0043 17.8 0.3 3.1 2 1 1 3 3 3 2 zinc-ribbon family zinc_ribbon_2 PF13240.6 KXS17386.1 - 3.3e-05 23.4 17.8 0.00035 20.2 8.7 3.9 3 1 1 4 4 4 2 zinc-ribbon domain zf-ribbon_3 PF13248.6 KXS17386.1 - 3.4e-05 23.1 4.0 3.4e-05 23.1 4.0 3.4 3 0 0 3 3 3 1 zinc-ribbon domain DZR PF12773.7 KXS17386.1 - 9.7e-05 22.3 0.3 9.7e-05 22.3 0.3 3.3 2 1 0 2 2 2 1 Double zinc ribbon Rad50_zn_hook PF04423.14 KXS17386.1 - 0.00036 20.3 2.9 0.3 11.0 0.0 3.4 3 0 0 3 3 3 1 Rad50 zinc hook motif zf-C2H2_4 PF13894.6 KXS17386.1 - 0.011 16.6 3.0 0.011 16.6 3.0 4.2 3 1 1 4 4 4 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KXS17386.1 - 0.013 15.8 0.1 0.013 15.8 0.1 3.0 4 0 0 4 4 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 KXS17386.1 - 0.014 15.8 1.1 0.014 15.8 1.1 4.2 4 0 0 4 4 4 0 Zinc finger, C2H2 type DUF2318 PF10080.9 KXS17386.1 - 0.031 14.4 3.9 3.1 8.0 0.0 3.1 2 1 1 3 3 3 0 Predicted membrane protein (DUF2318) zinc-ribbons_6 PF07191.12 KXS17386.1 - 0.031 14.3 7.4 3.8 7.6 0.3 3.3 3 0 0 3 3 3 0 zinc-ribbons PhnA_Zn_Ribbon PF08274.12 KXS17386.1 - 0.051 13.5 6.8 1.4 8.9 0.0 3.9 4 0 0 4 4 4 0 PhnA Zinc-Ribbon DUF2256 PF10013.9 KXS17386.1 - 0.12 12.5 11.8 14 5.9 0.1 4.3 3 1 1 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2256) NRDD PF13597.6 KXS17386.1 - 0.13 11.0 1.6 7.2 5.3 0.9 2.3 2 0 0 2 2 2 0 Anaerobic ribonucleoside-triphosphate reductase zinc_ribbon_4 PF13717.6 KXS17386.1 - 0.17 11.8 9.0 6.7 6.7 0.1 4.0 4 0 0 4 4 4 0 zinc-ribbon domain zinc_ribbon_9 PF14369.6 KXS17386.1 - 0.34 11.2 0.1 0.34 11.2 0.1 4.2 4 1 1 5 5 4 0 zinc-ribbon TF_Zn_Ribbon PF08271.12 KXS17386.1 - 0.39 10.3 10.0 1.9 8.0 3.0 3.4 3 0 0 3 3 3 0 TFIIB zinc-binding zf_UBZ PF18439.1 KXS17386.1 - 0.42 10.3 11.5 21 4.8 0.8 4.4 3 1 1 4 4 4 0 Ubiquitin-Binding Zinc Finger Nudix_N_2 PF14803.6 KXS17386.1 - 0.47 10.4 22.3 1.2 9.1 0.2 4.6 4 1 2 6 6 6 0 Nudix N-terminal Prok-RING_1 PF14446.6 KXS17386.1 - 0.58 10.1 9.4 5.1 7.1 1.7 3.4 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 tRNA-synt_1g PF09334.11 KXS17386.1 - 0.81 8.4 2.9 4 6.1 0.1 2.1 2 0 0 2 2 2 0 tRNA synthetases class I (M) Zn-ribbon_8 PF09723.10 KXS17386.1 - 0.86 9.8 15.2 15 5.8 0.0 4.4 3 2 1 4 4 4 0 Zinc ribbon domain Cript PF10235.9 KXS17386.1 - 0.86 10.2 6.6 1.8 9.2 0.1 3.1 3 1 0 3 3 3 0 Microtubule-associated protein CRIPT zf-Di19 PF05605.12 KXS17386.1 - 1.2 9.5 9.9 1.5 9.1 0.6 3.3 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding FYVE PF01363.21 KXS17386.1 - 1.8 8.7 11.6 8.3 6.6 0.7 3.4 3 0 0 3 3 3 0 FYVE zinc finger HypA PF01155.19 KXS17386.1 - 2 8.5 9.7 2.3 8.3 0.5 3.0 2 1 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA FYDLN_acid PF09538.10 KXS17386.1 - 2.3 8.9 13.1 17 6.2 0.2 3.6 2 2 1 3 3 3 0 Protein of unknown function (FYDLN_acid) zf-H2C2_2 PF13465.6 KXS17386.1 - 2.3 8.8 11.2 17 6.1 0.1 4.4 3 1 1 4 4 4 0 Zinc-finger double domain DUF2116 PF09889.9 KXS17386.1 - 2.9 8.0 10.0 0.22 11.5 0.5 3.0 3 0 0 3 3 3 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) UPF0547 PF10571.9 KXS17386.1 - 4.3 7.5 22.2 0.28 11.3 0.7 5.0 5 0 0 5 5 5 0 Uncharacterised protein family UPF0547 NOB1_Zn_bind PF08772.11 KXS17386.1 - 4.4 7.6 14.5 9.1 6.5 0.6 3.9 4 0 0 4 4 4 0 Nin one binding (NOB1) Zn-ribbon like ABC_ATPase PF09818.9 KXS17387.1 - 4.9e-127 424.4 0.0 6.4e-127 424.0 0.0 1.1 1 0 0 1 1 1 1 Predicted ATPase of the ABC class AAA_25 PF13481.6 KXS17387.1 - 0.001 18.7 0.0 0.0029 17.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain Peptidase_C97 PF05903.14 KXS17388.1 - 1.6e-41 141.6 0.0 2.3e-41 141.1 0.0 1.2 1 0 0 1 1 1 1 PPPDE putative peptidase domain PUL PF08324.11 KXS17388.1 - 9.8e-27 93.9 0.1 1.7e-26 93.1 0.1 1.2 1 0 0 1 1 1 1 PUL domain Thioredoxin PF00085.20 KXS17388.1 - 7.7e-09 35.5 0.0 3.6e-08 33.3 0.0 1.9 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KXS17388.1 - 0.00025 21.5 0.0 0.00069 20.0 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin-like domain DEC-1_N PF04625.13 KXS17388.1 - 0.05 12.6 1.6 0.078 12.0 1.6 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region DUF3948 PF13134.6 KXS17389.1 - 0.056 13.1 0.1 0.17 11.6 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3948) MFS_1 PF07690.16 KXS17392.1 - 4.1e-26 91.8 32.5 5.2e-26 91.4 32.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MDD_C PF18376.1 KXS17393.1 - 6.5e-63 211.9 0.0 9.6e-63 211.3 0.0 1.3 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 KXS17393.1 - 1.8e-07 31.2 2.6 5.9e-07 29.6 2.6 1.9 1 0 0 1 1 1 1 GHMP kinases N terminal domain PDGLE PF13190.6 KXS17393.1 - 0.075 12.9 0.1 0.18 11.7 0.1 1.6 1 0 0 1 1 1 0 PDGLE domain zf-BED PF02892.15 KXS17396.1 - 5.8 7.0 6.9 19 5.4 6.2 2.2 2 1 0 2 2 2 0 BED zinc finger EOS1 PF12326.8 KXS17397.1 - 0.1 12.5 0.9 0.15 12.0 0.9 1.5 1 1 0 1 1 1 0 N-glycosylation protein Ses_B PF17046.5 KXS17397.1 - 0.11 12.5 0.7 4.8 7.2 0.2 2.4 2 0 0 2 2 2 0 SesB domain on fungal death-pathway protein FWWh PF14922.6 KXS17398.1 - 0.034 14.1 0.1 0.045 13.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function LRR_8 PF13855.6 KXS17399.1 - 4.9e-06 26.2 7.7 9.4e-06 25.3 1.5 2.3 1 1 1 2 2 2 2 Leucine rich repeat SH3_9 PF14604.6 KXS17399.1 - 0.008 16.0 0.0 0.067 13.1 0.0 2.4 2 0 0 2 2 2 1 Variant SH3 domain LRR_4 PF12799.7 KXS17399.1 - 0.012 16.0 14.5 1.3 9.5 0.4 3.4 1 1 3 4 4 4 0 Leucine Rich repeats (2 copies) SH3_1 PF00018.28 KXS17399.1 - 0.042 13.5 0.0 0.1 12.2 0.0 1.6 1 0 0 1 1 1 0 SH3 domain LRR_1 PF00560.33 KXS17399.1 - 0.14 12.8 4.9 1.1 10.1 0.0 3.9 3 0 0 3 3 3 0 Leucine Rich Repeat TMEM210 PF15195.6 KXS17399.1 - 0.46 10.9 5.4 0.28 11.6 2.8 1.8 1 1 1 2 2 2 0 TMEM210 family VIT1 PF01988.19 KXS17400.1 - 1.2e-49 169.1 3.8 1.4e-49 168.9 3.8 1.0 1 0 0 1 1 1 1 VIT family pPIWI_RE_Y PF18156.1 KXS17400.1 - 0.13 12.7 0.0 0.18 12.2 0.0 1.2 1 0 0 1 1 1 0 pPIWI_RE three-gene island domain Y LRR_8 PF13855.6 KXS17402.1 - 9.9e-06 25.2 0.1 1.6e-05 24.6 0.1 1.4 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 KXS17402.1 - 0.0025 18.2 1.1 0.15 12.5 0.9 2.3 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) Peptidase_S24 PF00717.23 KXS17403.1 - 8.2e-10 38.5 0.0 1.3e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase S24-like NmrA PF05368.13 KXS17404.1 - 9.2e-12 45.0 0.1 2.2e-11 43.8 0.1 1.5 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXS17404.1 - 1.4e-07 31.6 0.0 3e-07 30.5 0.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding ERF PF04404.12 KXS17404.1 - 0.037 13.9 0.0 0.057 13.3 0.0 1.2 1 0 0 1 1 1 0 ERF superfamily LpxI_N PF17930.1 KXS17404.1 - 0.1 12.5 0.3 0.27 11.2 0.1 1.8 2 0 0 2 2 2 0 LpxI N-terminal domain BolA PF01722.18 KXS17405.1 - 1.4e-28 99.0 0.1 1.6e-28 98.8 0.1 1.1 1 0 0 1 1 1 1 BolA-like protein Haem_degrading PF03928.14 KXS17405.1 - 0.14 12.2 0.0 0.2 11.7 0.0 1.2 1 0 0 1 1 1 0 Haem-degrading Fasciclin PF02469.22 KXS17406.1 - 8.1e-16 58.4 0.0 5.8e-08 33.0 0.0 2.2 2 0 0 2 2 2 2 Fasciclin domain DUF3262 PF11660.8 KXS17406.1 - 0.11 12.9 0.0 0.27 11.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3262) LRR_4 PF12799.7 KXS17407.1 - 7.8e-08 32.5 7.1 0.009 16.4 1.6 3.4 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXS17407.1 - 0.046 13.5 4.0 0.081 12.7 0.1 2.4 1 1 1 2 2 2 0 Leucine rich repeat PAP_PilO PF06864.12 KXS17407.1 - 0.048 12.5 0.1 0.071 11.9 0.1 1.1 1 0 0 1 1 1 0 Pilin accessory protein (PilO) DUF4381 PF14316.6 KXS17407.1 - 0.27 11.5 1.4 0.49 10.6 1.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) FeoB_associated PF12669.7 KXS17407.1 - 4.9 7.6 5.0 1.6 9.2 0.1 2.2 2 0 0 2 2 2 0 FeoB-associated Cys-rich membrane protein SH3_1 PF00018.28 KXS17408.1 - 0.00064 19.3 0.0 0.0026 17.3 0.0 2.1 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 KXS17408.1 - 0.0031 17.3 0.0 0.0068 16.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain LRR_4 PF12799.7 KXS17408.1 - 0.011 16.1 0.0 0.48 10.9 0.1 2.5 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) SKG6 PF08693.10 KXS17408.1 - 0.045 13.2 2.1 0.079 12.4 2.1 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain SH3_2 PF07653.17 KXS17408.1 - 0.047 13.4 0.0 0.56 9.9 0.0 2.5 2 0 0 2 2 2 0 Variant SH3 domain LRR_4 PF12799.7 KXS17409.1 - 1.7e-06 28.3 2.7 0.00098 19.5 0.2 3.2 2 1 0 2 2 2 2 Leucine Rich repeats (2 copies) Herpes_gE PF02480.16 KXS17409.1 - 0.0025 16.7 0.0 0.0038 16.0 0.0 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E SH3_9 PF14604.6 KXS17409.1 - 0.11 12.4 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain SH3_2 PF07653.17 KXS17409.1 - 0.15 11.8 0.0 0.31 10.7 0.0 1.6 1 0 0 1 1 1 0 Variant SH3 domain Gram_pos_anchor PF00746.21 KXS17409.1 - 2.6 8.1 4.3 5.1 7.1 4.3 1.5 1 0 0 1 1 1 0 LPXTG cell wall anchor motif LRR_8 PF13855.6 KXS17409.1 - 3.3 7.5 5.8 1.6 8.6 0.1 2.7 2 1 1 3 3 3 0 Leucine rich repeat LRR_4 PF12799.7 KXS17410.1 - 0.00013 22.3 8.7 0.12 12.8 0.2 3.3 1 1 3 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXS17410.1 - 0.0002 21.1 0.1 0.00062 19.5 0.0 1.9 2 0 0 2 2 2 1 Leucine rich repeat Phage_holin_2_4 PF16082.5 KXS17410.1 - 0.095 12.4 2.0 0.25 11.1 2.0 1.7 1 1 0 1 1 1 0 Bacteriophage holin family, superfamily II-like LRR_1 PF00560.33 KXS17410.1 - 1.4 9.7 3.5 87 4.3 0.2 3.8 2 2 0 2 2 2 0 Leucine Rich Repeat CENP-X PF09415.10 KXS17414.1 - 0.28 11.5 2.3 0.36 11.2 2.2 1.4 1 1 0 1 1 1 0 CENP-S associating Centromere protein X PNK3P PF08645.11 KXS17415.1 - 7.4e-50 168.8 0.0 1.2e-49 168.1 0.0 1.3 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.6 KXS17415.1 - 4.3e-14 52.9 0.1 2.8e-11 43.7 0.1 2.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KXS17415.1 - 0.0014 19.0 0.0 0.0028 18.0 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 KXS17415.1 - 0.0037 16.6 0.0 0.0071 15.6 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin Hydrolase_like PF13242.6 KXS17415.1 - 0.0041 17.2 0.1 0.02 14.9 0.0 2.2 2 0 0 2 2 2 1 HAD-hyrolase-like AAA PF00004.29 KXS17415.1 - 0.0097 16.3 0.0 0.024 15.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Hydrolase_6 PF13344.6 KXS17415.1 - 0.13 12.4 0.0 1.2 9.3 0.0 2.4 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Glyoxalase_4 PF13669.6 KXS17416.1 - 0.00058 20.1 0.0 0.0027 18.0 0.0 2.1 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 KXS17416.1 - 0.00065 19.9 0.2 0.08 13.0 0.1 2.3 2 1 0 2 2 2 2 Glyoxalase-like domain Glyco_transf_8 PF01501.20 KXS17417.1 - 4.6e-13 49.3 0.0 8.2e-13 48.5 0.0 1.3 1 1 0 1 1 1 1 Glycosyl transferase family 8 PFK PF00365.20 KXS17418.1 - 4.5e-182 603.7 0.0 2.7e-94 315.7 0.0 2.1 2 0 0 2 2 2 2 Phosphofructokinase DUF366 PF04017.12 KXS17418.1 - 0.036 13.6 0.0 4.7 6.6 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF366) RRM_1 PF00076.22 KXS17419.1 - 5.3e-19 67.8 0.0 8.9e-19 67.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) U1snRNP70_N PF12220.8 KXS17419.1 - 1.3e-17 64.2 4.0 1.3e-17 64.2 4.0 1.8 2 0 0 2 2 2 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_8 PF11835.8 KXS17419.1 - 0.19 12.0 0.0 0.32 11.2 0.0 1.2 1 0 0 1 1 1 0 RRM-like domain DUF953 PF06110.11 KXS17420.1 - 2.1e-18 66.1 0.0 2.8e-18 65.6 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Sulfatase PF00884.23 KXS17421.1 - 1.5e-62 211.8 0.2 2.2e-62 211.2 0.2 1.3 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KXS17421.1 - 1.2e-05 25.1 1.5 0.14 11.7 1.1 2.1 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4976 PF16347.5 KXS17421.1 - 0.035 14.4 0.1 0.071 13.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4976) Ank_2 PF12796.7 KXS17422.1 - 0.00054 20.5 0.7 0.0034 17.9 0.2 2.1 1 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXS17422.1 - 0.0029 18.0 0.3 0.26 11.9 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 KXS17422.1 - 0.0076 16.5 1.2 0.077 13.3 0.7 2.5 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXS17422.1 - 0.073 13.7 0.6 6.1 7.6 0.8 3.0 2 1 1 3 3 3 0 Ankyrin repeats (many copies) NOB1_Zn_bind PF08772.11 KXS17423.1 - 0.16 12.1 10.1 13 6.0 4.6 3.3 3 0 0 3 3 3 0 Nin one binding (NOB1) Zn-ribbon like PRP21_like_P PF12230.8 KXS17424.1 - 6.1e-18 65.5 0.2 6.1e-18 65.5 0.2 1.8 2 1 0 2 2 2 1 Pre-mRNA splicing factor PRP21 like protein zf_UBZ PF18439.1 KXS17424.1 - 0.098 12.3 0.1 0.19 11.4 0.1 1.4 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger Pro_CA PF00484.19 KXS17425.1 - 8.3e-46 156.1 0.0 1.1e-45 155.7 0.0 1.2 1 0 0 1 1 1 1 Carbonic anhydrase Methyltransf_25 PF13649.6 KXS17426.1 - 0.00052 20.7 0.1 0.00094 19.8 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXS17426.1 - 0.0051 16.7 0.0 0.0062 16.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXS17426.1 - 0.014 15.2 0.0 0.025 14.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DOT1 PF08123.13 KXS17426.1 - 0.016 14.7 0.0 0.018 14.6 0.0 1.3 1 1 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_4 PF02390.17 KXS17426.1 - 0.05 13.1 0.0 0.071 12.6 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase CMAS PF02353.20 KXS17426.1 - 0.061 12.6 0.0 0.09 12.1 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.12 KXS17426.1 - 0.075 13.7 0.0 0.13 13.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain UPF0029 PF01205.19 KXS17428.1 - 1.1e-30 106.1 0.0 1.2e-30 105.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 Iso_dh PF00180.20 KXS17429.1 - 1.8e-127 425.3 0.0 2.1e-127 425.1 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase RasGEF PF00617.19 KXS17430.1 - 3.4e-38 131.6 0.1 6.7e-38 130.6 0.1 1.5 1 0 0 1 1 1 1 RasGEF domain PH_9 PF15410.6 KXS17430.1 - 2.4e-15 57.0 0.3 5.9e-15 55.7 0.0 1.7 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 KXS17430.1 - 1.2e-10 41.8 0.1 2.3e-10 40.9 0.1 1.4 1 0 0 1 1 1 1 PH domain PH_2 PF08458.10 KXS17430.1 - 0.11 12.9 0.7 0.99 9.8 0.1 2.3 2 0 0 2 2 2 0 Plant pleckstrin homology-like region Glyoxalase PF00903.25 KXS17430.1 - 0.16 12.2 0.0 0.45 10.7 0.0 1.8 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DIOX_N PF14226.6 KXS17432.1 - 4.6e-14 53.2 0.0 8.1e-14 52.4 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KXS17432.1 - 2.2e-13 50.5 0.0 4.4e-13 49.6 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Glyco_hydro_28 PF00295.17 KXS17433.1 - 5.9e-79 265.5 21.0 6.8e-79 265.3 21.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 VSP PF03302.13 KXS17434.1 - 0.0008 18.4 0.5 0.0011 17.9 0.5 1.2 1 0 0 1 1 1 1 Giardia variant-specific surface protein PTP_tm PF18861.1 KXS17434.1 - 0.01 15.9 0.7 0.014 15.4 0.7 1.2 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J EphA2_TM PF14575.6 KXS17434.1 - 0.16 12.8 0.2 0.26 12.2 0.2 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4805 PF16063.5 KXS17434.1 - 0.27 10.6 6.0 0.39 10.0 5.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4805) Carb_bind PF10645.9 KXS17435.1 - 0.0025 18.0 21.2 0.052 13.8 5.5 2.3 2 0 0 2 2 2 2 Carbohydrate binding zf-CCHC PF00098.23 KXS17436.1 - 1.4e-07 31.2 3.7 1.4e-07 31.2 3.7 2.1 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_4 PF14392.6 KXS17436.1 - 0.46 10.3 2.8 0.34 10.7 0.5 2.0 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_6 PF15288.6 KXS17436.1 - 0.72 9.7 5.8 0.35 10.8 2.7 2.0 2 0 0 2 2 2 0 Zinc knuckle DUF2075 PF09848.9 KXS17438.1 - 0.00037 19.8 0.1 0.00048 19.5 0.1 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Retrotran_gag_2 PF14223.6 KXS17438.1 - 0.00075 19.2 0.1 0.0011 18.6 0.1 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type BCA_ABC_TP_C PF12399.8 KXS17439.1 - 0.13 12.3 1.6 0.17 11.9 0.2 1.8 2 0 0 2 2 2 0 Branched-chain amino acid ATP-binding cassette transporter OPT PF03169.15 KXS17440.1 - 1.8e-12 46.8 26.8 2.7e-06 26.3 1.7 4.0 2 1 2 4 4 4 4 OPT oligopeptide transporter protein GATA PF00320.27 KXS17441.1 - 5.3e-09 35.5 3.2 1.1e-08 34.5 3.2 1.5 1 0 0 1 1 1 1 GATA zinc finger PriCT_1 PF08708.11 KXS17441.1 - 0.11 12.2 0.2 0.51 10.1 0.1 2.0 2 0 0 2 2 2 0 Primase C terminal 1 (PriCT-1) Pkinase PF00069.25 KXS17442.1 - 3.5e-17 62.6 0.0 3.6e-17 62.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS17442.1 - 7.8e-11 41.8 0.0 8.7e-11 41.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Sel1 PF08238.12 KXS17443.1 - 4.5e-38 128.8 13.9 7.7e-12 45.5 0.2 5.1 5 0 0 5 5 5 5 Sel1 repeat Fib_succ_major PF09603.10 KXS17443.1 - 0.11 13.1 4.6 2.8 8.5 0.7 2.6 1 1 1 2 2 2 0 Fibrobacter succinogenes major domain (Fib_succ_major) PurK_C PF17769.1 KXS17443.1 - 0.14 11.8 0.0 1.8 8.3 0.0 2.4 1 1 1 2 2 2 0 Phosphoribosylaminoimidazole carboxylase C-terminal domain DUF5393 PF17371.2 KXS17444.1 - 0.029 12.5 1.9 0.049 11.8 1.9 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5393) Pkinase_Tyr PF07714.17 KXS17445.1 - 7.4e-12 45.1 0.0 8.5e-12 44.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXS17445.1 - 7.8e-05 22.2 0.0 8.7e-05 22.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain DUF3263 PF11662.8 KXS17445.1 - 0.049 13.5 0.7 0.049 13.5 0.7 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3263) LRR_6 PF13516.6 KXS17446.1 - 3.5e-43 142.0 35.5 1.1e-06 28.2 0.1 10.5 10 0 0 10 10 10 8 Leucine Rich repeat Pkinase PF00069.25 KXS17446.1 - 7.3e-21 74.7 0.0 1.1e-20 74.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS17446.1 - 4.1e-13 49.2 0.0 6.1e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_1 PF00560.33 KXS17446.1 - 5.6e-09 35.3 2.3 16 6.5 0.0 7.6 8 0 0 8 8 8 0 Leucine Rich Repeat LRR_4 PF12799.7 KXS17446.1 - 2.4e-08 34.1 29.3 0.00085 19.7 1.2 6.2 2 2 5 7 7 7 7 Leucine Rich repeats (2 copies) SpoU_sub_bind PF08032.12 KXS17446.1 - 9.1e-06 25.9 2.9 4.5 7.6 0.0 5.8 5 3 1 6 6 6 2 RNA 2'-O ribose methyltransferase substrate binding Sas10 PF09368.10 KXS17446.1 - 1.4e-05 25.5 4.4 54 4.4 0.0 7.0 8 0 0 8 8 8 0 Sas10 C-terminal domain LRR_8 PF13855.6 KXS17446.1 - 0.0007 19.3 25.9 0.58 10.0 6.5 6.2 2 2 3 5 5 5 4 Leucine rich repeat DUF3726 PF12525.8 KXS17446.1 - 0.00079 19.5 1.5 7.7 6.7 0.1 5.0 2 2 0 2 2 2 1 Protein of unknown function (DUF3726) Kdo PF06293.14 KXS17446.1 - 0.069 12.5 0.1 0.2 11.0 0.1 1.8 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family GARS_N PF02844.15 KXS17446.1 - 1 10.2 4.8 21 6.0 0.5 4.0 3 2 0 4 4 3 0 Phosphoribosylglycinamide synthetase, N domain Ank_2 PF12796.7 KXS17446.1 - 2 9.1 6.5 0.76 10.4 0.5 3.2 2 1 1 4 4 3 0 Ankyrin repeats (3 copies) Sel1 PF08238.12 KXS17447.1 - 4.6e-75 246.3 20.8 1.6e-10 41.3 0.0 8.1 8 0 0 8 8 8 8 Sel1 repeat ANAPC3 PF12895.7 KXS17447.1 - 0.00016 21.8 0.5 5.9 7.2 0.0 5.0 3 2 2 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 Fib_succ_major PF09603.10 KXS17447.1 - 0.0013 19.5 22.7 1 9.9 1.2 6.0 1 1 4 5 5 5 2 Fibrobacter succinogenes major domain (Fib_succ_major) TPR_6 PF13174.6 KXS17447.1 - 0.042 14.5 1.8 75 4.3 0.0 4.8 6 0 0 6 6 6 0 Tetratricopeptide repeat Capsule_synth PF05159.14 KXS17447.1 - 0.36 10.2 5.5 1.1 8.6 0.1 3.7 1 1 5 6 6 6 0 Capsule polysaccharide biosynthesis protein zf-C2H2 PF00096.26 KXS17448.1 - 5.5e-14 51.7 21.5 8.5e-07 29.1 0.6 4.0 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KXS17448.1 - 6e-12 45.4 15.6 0.00015 22.0 1.1 4.2 4 0 0 4 4 4 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 KXS17448.1 - 1.2e-07 31.9 18.2 0.0003 21.4 0.4 3.8 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KXS17448.1 - 3e-05 24.2 0.3 0.038 14.3 0.0 3.1 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 KXS17448.1 - 4e-05 23.8 6.2 0.04 14.2 1.3 2.2 1 1 1 2 2 2 2 C2H2-type zinc ribbon zf-met PF12874.7 KXS17448.1 - 0.0002 21.6 6.2 1.3 9.5 0.1 4.4 3 2 1 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KXS17448.1 - 0.0033 17.4 10.6 0.018 15.0 0.2 3.9 4 2 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 KXS17448.1 - 0.024 14.8 10.9 0.24 11.5 1.7 3.2 2 1 1 3 3 3 0 Aberrant zinc-finger zf_Hakai PF18408.1 KXS17448.1 - 0.074 12.8 9.4 0.37 10.5 0.2 4.0 4 0 0 4 4 4 0 C2H2 Hakai zinc finger domain DUF3268 PF11672.8 KXS17448.1 - 0.075 13.4 4.1 0.5 10.7 0.4 2.1 2 0 0 2 2 2 0 zinc-finger-containing domain FOXP-CC PF16159.5 KXS17448.1 - 0.083 13.5 5.1 15 6.3 0.2 3.1 1 1 2 3 3 3 0 FOXP coiled-coil domain Sel1 PF08238.12 KXS17449.1 - 1.6e-110 359.0 99.9 1.4e-07 32.0 0.8 23.1 23 1 0 23 23 23 20 Sel1 repeat RNA_pol_3_Rpc31 PF11705.8 KXS17450.1 - 1.7e-12 48.1 15.3 1.1e-10 42.1 15.3 2.0 1 1 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 VIR_N PF15912.5 KXS17450.1 - 0.47 10.0 8.5 0.67 9.5 8.5 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal KAR9 PF08580.10 KXS17452.1 - 2.8 6.4 4.9 2.9 6.3 4.9 1.0 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Ank_2 PF12796.7 KXS17454.1 - 3.9e-06 27.4 0.0 0.23 12.1 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXS17454.1 - 0.00029 21.3 0.1 0.31 11.7 0.2 2.9 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXS17454.1 - 0.0015 18.9 0.1 17 6.4 0.0 4.2 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 KXS17454.1 - 0.0037 17.5 1.1 32 5.0 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXS17455.1 - 5.9e-06 26.8 1.7 0.00057 20.4 1.8 3.0 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXS17455.1 - 0.00017 21.8 1.5 7.3 7.5 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 KXS17455.1 - 0.049 14.1 2.6 1.1 9.8 0.2 3.2 3 0 0 3 3 3 0 Ankyrin repeat Ank_4 PF13637.6 KXS17455.1 - 0.23 12.1 3.1 1 10.1 0.4 2.8 3 1 0 3 3 3 0 Ankyrin repeats (many copies) CPSase_L_D2 PF02786.17 KXS17457.1 - 1.6e-101 338.2 0.1 7.4e-85 283.7 0.0 3.1 2 1 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 KXS17457.1 - 6e-39 133.2 0.1 2.5e-38 131.2 0.1 2.1 1 1 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain Dala_Dala_lig_C PF07478.13 KXS17457.1 - 2.5e-15 56.6 0.7 7.8e-09 35.4 0.1 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KXS17457.1 - 2.5e-15 56.5 0.2 3.5e-08 33.2 0.0 2.9 2 1 1 3 3 3 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 KXS17457.1 - 4.6e-06 26.4 0.0 0.046 13.5 0.0 3.4 3 1 0 3 3 3 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.14 KXS17457.1 - 1.4e-05 25.2 0.2 0.012 15.7 0.1 2.4 2 0 0 2 2 2 2 ATP-grasp domain GARS_A PF01071.19 KXS17457.1 - 5.6e-05 23.0 0.2 0.29 10.9 0.0 2.4 2 0 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RimK PF08443.11 KXS17457.1 - 0.00013 21.6 0.0 0.64 9.6 0.0 2.6 2 1 0 2 2 2 2 RimK-like ATP-grasp domain ATP-grasp_5 PF13549.6 KXS17457.1 - 0.00041 19.9 0.1 0.079 12.4 0.0 2.5 2 0 0 2 2 2 1 ATP-grasp domain DUF3215 PF11503.8 KXS17457.1 - 0.0021 17.9 0.1 0.0084 15.9 0.1 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3215) DSPn PF14671.6 KXS17458.1 - 3.8e-47 160.3 0.0 8.5e-47 159.1 0.0 1.6 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 KXS17458.1 - 1.7e-13 50.5 0.0 9.4e-13 48.1 0.0 2.1 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KXS17458.1 - 9.9e-05 22.0 0.0 0.00017 21.3 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 KXS17458.1 - 0.0011 19.1 0.0 0.002 18.3 0.0 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 KXS17458.1 - 0.2 11.6 0.0 0.33 10.9 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family DDE_Tnp_4 PF13359.6 KXS17460.1 - 3.4e-09 36.5 0.0 4.1e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease ABC_membrane PF00664.23 KXS17462.1 - 5.7e-67 226.2 18.2 7.8e-49 166.8 6.2 3.1 2 1 1 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.27 KXS17462.1 - 2.9e-35 121.7 0.0 5.8e-21 75.4 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KXS17462.1 - 1.9e-10 40.6 0.0 1.5e-05 24.6 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 KXS17462.1 - 0.0016 18.6 3.8 1.2 9.4 0.5 3.8 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit ABC_ATPase PF09818.9 KXS17462.1 - 0.084 11.7 0.8 3.7 6.3 0.2 2.2 2 0 0 2 2 2 0 Predicted ATPase of the ABC class SUIM_assoc PF16619.5 KXS17463.1 - 2.4 8.3 8.0 2.1 8.5 1.1 2.8 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 LMP PF04778.12 KXS17465.1 - 0.25 11.2 3.7 2.3 8.1 3.7 1.9 1 1 0 1 1 1 0 LMP repeated region Glyoxalase PF00903.25 KXS17467.1 - 7.5e-07 29.4 0.0 0.019 15.1 0.0 2.2 1 1 1 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 KXS17467.1 - 8e-06 26.6 0.1 7.5e-05 23.5 0.0 2.4 2 2 0 2 2 2 1 Glyoxalase-like domain MFS_1 PF07690.16 KXS17469.1 - 2.2e-50 171.6 46.2 6e-49 166.8 47.4 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KXS17469.1 - 3.2e-19 68.8 16.4 4.3e-19 68.4 16.4 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KXS17469.1 - 1.9e-10 40.2 24.3 9.3e-09 34.6 10.1 2.6 2 1 0 2 2 2 2 Sugar (and other) transporter OATP PF03137.20 KXS17469.1 - 0.00059 18.3 13.5 0.006 14.9 1.2 3.1 3 0 0 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family Glyoxalase_6 PF18029.1 KXS17470.1 - 4.4e-07 30.7 0.0 5.6e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.25 KXS17470.1 - 2.4e-06 27.8 0.0 1.7e-05 25.0 0.0 1.9 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Gemini_mov PF01708.16 KXS17472.1 - 0.072 12.9 0.0 0.087 12.6 0.0 1.1 1 0 0 1 1 1 0 Geminivirus putative movement protein OTU PF02338.19 KXS17473.1 - 0.00016 22.2 0.4 0.00043 20.8 0.0 1.9 2 0 0 2 2 2 1 OTU-like cysteine protease Mitoc_mL59 PF18126.1 KXS17473.1 - 0.0034 17.7 1.4 0.0034 17.7 1.4 2.1 2 0 0 2 2 2 1 Mitochondrial ribosomal protein mL59 Oxysterol_BP PF01237.18 KXS17473.1 - 0.17 10.7 2.4 0.24 10.2 2.4 1.2 1 0 0 1 1 1 0 Oxysterol-binding protein Eapp_C PF10238.9 KXS17473.1 - 1 9.5 4.3 1.7 8.7 4.3 1.3 1 0 0 1 1 1 0 E2F-associated phosphoprotein CTNNB1_binding PF08347.11 KXS17473.1 - 2.1 8.5 6.6 0.12 12.5 0.6 1.9 2 0 0 2 2 2 0 N-terminal CTNNB1 binding G_path_suppress PF15991.5 KXS17473.1 - 6.5 6.8 14.0 0.14 12.3 3.6 2.3 2 0 0 2 2 2 0 G-protein pathway suppressor AA_permease_2 PF13520.6 KXS17474.1 - 4.7e-51 173.9 62.9 6.1e-51 173.6 62.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXS17474.1 - 1.9e-19 69.6 52.8 2.6e-19 69.2 52.8 1.0 1 0 0 1 1 1 1 Amino acid permease ABC2_membrane_3 PF12698.7 KXS17476.1 - 7.7e-30 104.2 27.3 7.7e-30 104.2 27.3 1.7 2 0 0 2 2 2 1 ABC-2 family transporter protein ABC_tran PF00005.27 KXS17476.1 - 6.9e-24 84.9 0.0 1.5e-23 83.8 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KXS17476.1 - 6.2e-07 29.5 0.1 0.021 14.6 0.0 2.9 2 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane PF01061.24 KXS17476.1 - 3.2e-05 23.5 20.6 3.2e-05 23.5 20.6 2.3 2 0 0 2 2 2 1 ABC-2 type transporter RsgA_GTPase PF03193.16 KXS17476.1 - 0.0051 16.7 0.0 0.015 15.2 0.0 1.7 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 KXS17476.1 - 0.038 13.7 0.2 0.1 12.4 0.2 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain QLQ PF08880.11 KXS17476.1 - 0.098 12.4 1.7 0.28 11.0 1.7 1.8 1 0 0 1 1 1 0 QLQ AAA_23 PF13476.6 KXS17476.1 - 0.16 12.5 0.3 0.38 11.2 0.3 1.5 1 0 0 1 1 1 0 AAA domain ABC2_membrane_5 PF13346.6 KXS17476.1 - 2.8 7.4 26.4 0.35 10.4 21.7 1.7 2 0 0 2 2 2 0 ABC-2 family transporter protein Pribosyltran_N PF13793.6 KXS17477.1 - 9.2e-45 151.3 0.2 2.1e-43 146.9 0.0 2.4 3 0 0 3 3 3 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 KXS17477.1 - 3.8e-37 128.1 2.5 1e-30 107.1 1.0 2.3 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 KXS17477.1 - 3.3e-07 30.0 0.6 1e-05 25.1 0.3 2.4 2 1 0 2 2 2 1 Phosphoribosyl transferase domain Myb_DNA-binding PF00249.31 KXS17479.1 - 3.9e-17 62.2 16.4 7.2e-09 35.7 0.0 5.5 5 1 0 5 5 5 4 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KXS17479.1 - 2.7e-14 53.1 6.7 3e-10 40.2 0.0 4.2 3 2 1 4 4 4 2 Myb-like DNA-binding domain DUF5053 PF16476.5 KXS17479.1 - 0.0047 16.5 1.3 5 6.8 0.0 4.2 4 0 0 4 4 4 1 Domain of unknown function (DUF5053) Histone_HNS PF00816.21 KXS17479.1 - 0.069 14.0 0.1 0.069 14.0 0.1 2.9 3 1 0 3 3 3 0 H-NS histone family Mis14 PF08641.12 KXS17479.1 - 0.099 13.0 5.8 0.27 11.6 5.8 1.8 1 0 0 1 1 1 0 Kinetochore protein Mis14 like DUF573 PF04504.14 KXS17479.1 - 0.22 12.2 5.6 14 6.5 3.8 3.5 2 1 0 2 2 2 0 Protein of unknown function, DUF573 Fer2_3 PF13085.6 KXS17480.1 - 1.1e-33 115.5 0.0 1.8e-33 114.8 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 KXS17480.1 - 4.5e-09 36.7 6.1 4.5e-09 36.7 6.1 2.3 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 KXS17480.1 - 1.1e-06 28.6 3.9 1.1e-06 28.6 3.9 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 KXS17480.1 - 2.8e-06 27.7 12.1 1.7e-05 25.2 9.8 2.5 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer2 PF00111.27 KXS17480.1 - 0.0027 17.6 3.1 0.0038 17.1 0.2 2.2 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_7 PF12838.7 KXS17480.1 - 0.043 14.4 9.1 0.043 14.4 9.1 2.9 2 2 0 2 2 2 0 4Fe-4S dicluster domain Fer4_9 PF13187.6 KXS17480.1 - 0.42 10.8 14.0 0.12 12.6 8.1 2.7 2 1 0 2 2 2 0 4Fe-4S dicluster domain Fer4_18 PF13746.6 KXS17480.1 - 1.1 9.5 5.8 0.72 10.1 0.1 2.5 3 0 0 3 3 3 0 4Fe-4S dicluster domain Fer4_16 PF13484.6 KXS17480.1 - 1.4 10.0 11.4 3 8.8 1.0 3.0 3 1 0 3 3 3 0 4Fe-4S double cluster binding domain Cytochrom_B561 PF03188.16 KXS17481.1 - 6.7e-12 45.7 4.5 1.3e-11 44.7 4.5 1.5 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 Fungus-induced PF10917.8 KXS17481.1 - 0.046 14.0 0.1 0.2 12.0 0.0 2.1 2 0 0 2 2 2 0 Fungus-induced protein DUF572 PF04502.13 KXS17483.1 - 1.4e-76 258.3 0.0 1.8e-76 257.9 0.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) Bac_rhamnosid_N PF08531.10 KXS17485.1 - 2.3e-10 40.6 1.5 1.7e-09 37.7 1.5 2.3 1 1 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain Bac_rhamnosid_C PF17390.2 KXS17485.1 - 3.3e-05 23.6 0.2 0.0006 19.6 0.2 2.4 1 1 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain Apt1 PF10351.9 KXS17485.1 - 2.3 7.0 7.1 3.5 6.4 7.1 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain SlyX PF04102.12 KXS17487.1 - 0.09 13.4 19.3 0.32 11.7 0.0 4.9 5 1 0 5 5 5 0 SlyX IES5 PF17335.2 KXS17487.1 - 0.51 10.6 11.4 0.054 13.8 1.4 3.5 2 1 0 4 4 4 0 Ino80 complex subunit 5 F-box-like PF12937.7 KXS17489.1 - 2.1e-07 30.7 0.6 2.1e-07 30.7 0.6 1.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KXS17489.1 - 2.8e-06 27.0 1.6 6.3e-06 25.9 1.6 1.7 1 0 0 1 1 1 1 F-box domain WD40 PF00400.32 KXS17489.1 - 0.13 13.2 1.7 0.3 12.0 0.6 2.2 2 0 0 2 2 2 0 WD domain, G-beta repeat Mon2_C PF16206.5 KXS17490.1 - 1e-37 129.8 0.9 4.1e-37 127.8 0.1 2.1 1 1 1 2 2 2 1 C-terminal region of Mon2 protein DCB PF16213.5 KXS17490.1 - 1.7e-31 109.2 0.0 6.1e-31 107.5 0.0 2.0 1 0 0 1 1 1 1 Dimerisation and cyclophilin-binding domain of Mon2 Sec7_N PF12783.7 KXS17490.1 - 2e-30 105.8 0.0 1e-29 103.5 0.0 2.4 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal ArfGap PF01412.18 KXS17490.1 - 3.7e-30 104.4 0.1 7.9e-30 103.3 0.1 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Takusan PF04822.13 KXS17490.1 - 0.096 12.6 0.1 3.4 7.6 0.0 2.6 2 0 0 2 2 2 0 Takusan CfAFP PF05264.11 KXS17490.1 - 0.14 12.2 0.5 0.45 10.5 0.5 1.9 1 0 0 1 1 1 0 Choristoneura fumiferana antifreeze protein (CfAFP) LRR_6 PF13516.6 KXS17491.1 - 1.3e-11 43.6 12.4 0.01 15.8 0.3 9.2 10 0 0 10 10 10 3 Leucine Rich repeat GAT PF03127.14 KXS17491.1 - 0.001 19.4 3.1 0.0055 17.0 3.1 2.3 1 0 0 1 1 1 1 GAT domain LRR_1 PF00560.33 KXS17491.1 - 0.015 15.8 11.7 2.3e+02 3.0 0.3 8.8 9 0 0 9 9 9 0 Leucine Rich Repeat LRR_4 PF12799.7 KXS17491.1 - 0.93 10.0 17.4 0.94 10.0 0.0 6.4 6 1 2 8 8 8 0 Leucine Rich repeats (2 copies) WD40 PF00400.32 KXS17492.1 - 9.1e-13 48.5 2.4 0.0042 17.9 0.1 4.6 4 0 0 4 4 4 3 WD domain, G-beta repeat DUF3506 PF12014.8 KXS17496.1 - 4.5e-17 62.3 0.3 2.3e-14 53.6 0.1 3.3 2 1 0 2 2 2 1 Domain of unknown function (DUF3506) F-box-like PF12937.7 KXS17496.1 - 5.8e-05 22.9 0.3 0.00011 22.0 0.3 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXS17496.1 - 0.048 13.6 0.0 0.097 12.6 0.0 1.5 1 0 0 1 1 1 0 F-box domain CHS5_N PF16892.5 KXS17497.1 - 8.6e-22 76.8 0.2 1.4e-21 76.1 0.2 1.4 1 0 0 1 1 1 1 Chitin biosynthesis protein CHS5 N-terminus fn3_2 PF16893.5 KXS17497.1 - 3.3e-21 75.2 0.0 5.6e-21 74.5 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III domain PTCB-BRCT PF12738.7 KXS17497.1 - 4.5e-10 39.3 0.0 7.9e-10 38.5 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 KXS17497.1 - 1.5e-08 34.9 0.1 4.2e-08 33.5 0.0 1.8 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain DUF3006 PF11213.8 KXS17497.1 - 6.6e-05 23.1 0.0 0.00023 21.3 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3006) fn3 PF00041.21 KXS17497.1 - 0.18 12.2 0.4 0.53 10.7 0.4 1.9 1 1 0 1 1 1 0 Fibronectin type III domain CybS PF05328.12 KXS17498.1 - 1e-33 115.9 0.1 1.2e-33 115.6 0.1 1.1 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit DEAD PF00270.29 KXS17499.1 - 1.4e-47 161.7 0.0 2.4e-47 161.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXS17499.1 - 2e-28 99.0 0.0 1.7e-27 96.0 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain GUCT PF08152.12 KXS17499.1 - 1.2e-19 70.3 0.0 3.1e-19 69.0 0.0 1.7 1 0 0 1 1 1 1 GUCT (NUC152) domain ResIII PF04851.15 KXS17499.1 - 1.5e-07 31.6 0.4 1.8e-06 28.0 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 KXS17499.1 - 2.2e-05 23.9 0.0 2.2e-05 23.9 0.0 3.2 2 1 1 3 3 3 1 U3-containing 90S pre-ribosomal complex subunit Rrn6 PF10214.9 KXS17499.1 - 0.15 10.5 7.3 0.21 10.0 7.3 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor GREB1 PF15782.5 KXS17499.1 - 9.7 3.1 5.2 12 2.8 5.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Mito_carr PF00153.27 KXS17500.1 - 1.4e-63 210.8 0.4 1.1e-22 79.7 0.1 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein PTPA PF03095.15 KXS17501.1 - 6.5e-122 406.7 0.0 7.6e-122 406.5 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Cullin PF00888.22 KXS17502.1 - 2e-27 96.1 0.0 3.7e-27 95.2 0.0 1.3 1 0 0 1 1 1 1 Cullin family ANAPC2 PF08672.11 KXS17502.1 - 0.0006 20.3 0.5 0.003 18.0 0.1 2.4 2 0 0 2 2 2 1 Anaphase promoting complex (APC) subunit 2 Rrf2 PF02082.20 KXS17502.1 - 0.0057 17.0 0.0 0.16 12.3 0.0 2.5 2 0 0 2 2 2 1 Transcriptional regulator MarR PF01047.22 KXS17502.1 - 0.063 13.2 0.4 1 9.3 0.0 2.8 3 0 0 3 3 3 0 MarR family HTH_DeoR PF08220.12 KXS17502.1 - 0.1 12.4 0.1 4.5 7.1 0.0 2.5 2 0 0 2 2 2 0 DeoR-like helix-turn-helix domain Ribosomal_L23eN PF03939.13 KXS17504.1 - 1.9e-22 79.2 10.2 1.9e-22 79.2 10.2 2.3 1 1 1 2 2 2 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 KXS17504.1 - 4.5e-14 52.6 2.8 4.5e-14 52.6 2.8 2.7 2 2 0 2 2 2 1 Ribosomal protein L23 LRR_4 PF12799.7 KXS17505.1 - 1.6e-39 133.2 54.4 5.7e-08 32.9 1.7 6.4 1 1 8 9 9 9 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXS17505.1 - 9.5e-23 79.7 31.9 4.7e-07 29.5 5.8 6.2 1 1 5 6 6 6 6 Leucine rich repeat LRR_9 PF14580.6 KXS17505.1 - 2.9e-16 59.4 16.6 3.8e-06 26.5 0.5 4.1 1 1 3 4 4 4 4 Leucine-rich repeat LRR_1 PF00560.33 KXS17505.1 - 0.004 17.5 26.0 11 7.1 0.4 9.0 7 3 0 7 7 7 2 Leucine Rich Repeat LRR_6 PF13516.6 KXS17505.1 - 0.17 12.0 28.5 1.1 9.4 0.3 8.0 8 1 1 9 9 9 0 Leucine Rich repeat zf-DNL PF05180.12 KXS17506.1 - 3e-27 94.3 0.3 4.6e-27 93.7 0.3 1.3 1 0 0 1 1 1 1 DNL zinc finger FAM72 PF14976.6 KXS17507.1 - 1.8e-45 154.6 1.9 2.2e-45 154.3 1.9 1.0 1 0 0 1 1 1 1 FAM72 protein Arm PF00514.23 KXS17508.1 - 0.00051 20.0 0.4 0.00051 20.0 0.4 2.9 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 KXS17508.1 - 0.06 13.7 1.7 0.17 12.3 0.5 2.4 2 0 0 2 2 2 0 HEAT repeats HEAT_EZ PF13513.6 KXS17508.1 - 0.07 13.7 0.2 1.6 9.3 0.3 3.2 2 0 0 2 2 2 0 HEAT-like repeat Fungal_trans PF04082.18 KXS17509.1 - 2.6e-16 59.5 0.7 4e-16 58.8 0.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXS17509.1 - 2.4e-08 34.0 13.0 4.5e-08 33.1 13.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sensor PF13796.6 KXS17510.1 - 5.6e-07 29.7 11.0 4e-05 23.7 4.1 2.5 2 0 0 2 2 2 2 Putative sensor TMEM72 PF16054.5 KXS17510.1 - 0.058 13.1 0.5 0.13 11.9 0.5 1.5 1 0 0 1 1 1 0 Transmembrane protein family 72 AAA PF00004.29 KXS17511.1 - 6.5e-17 62.2 0.0 2.3e-16 60.4 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KXS17511.1 - 6.1e-14 52.8 0.2 1.1e-12 48.7 0.1 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_lid_10 PF17872.1 KXS17511.1 - 2.4e-10 40.4 0.0 5e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 AAA lid domain AAA_22 PF13401.6 KXS17511.1 - 5.2e-10 39.7 0.0 1.5e-09 38.2 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KXS17511.1 - 0.00022 21.6 0.1 0.0005 20.4 0.1 1.7 1 1 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 KXS17511.1 - 0.0018 18.2 0.1 0.013 15.4 0.1 2.2 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_30 PF13604.6 KXS17511.1 - 0.0084 15.8 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.11 KXS17511.1 - 0.014 15.2 0.2 12 5.7 0.0 3.9 3 1 1 4 4 4 0 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 KXS17511.1 - 0.021 14.2 0.0 0.032 13.6 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_11 PF13086.6 KXS17511.1 - 0.028 14.2 0.0 0.049 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 KXS17511.1 - 0.032 14.0 0.0 0.061 13.1 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_5 PF07728.14 KXS17511.1 - 0.038 14.0 0.1 0.21 11.5 0.1 2.4 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) PIF1 PF05970.14 KXS17511.1 - 0.047 12.9 0.0 0.077 12.1 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase AAA_18 PF13238.6 KXS17511.1 - 0.049 14.2 0.0 0.11 13.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain TsaE PF02367.17 KXS17511.1 - 0.11 12.5 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 KXS17511.1 - 0.12 12.2 0.0 0.3 11.0 0.0 1.6 1 1 0 1 1 1 0 NACHT domain DUF2075 PF09848.9 KXS17511.1 - 0.14 11.3 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Rgp1 PF08737.10 KXS17512.1 - 6.2e-58 196.9 0.0 5.3e-29 101.6 0.0 3.1 1 1 2 3 3 3 3 Rgp1 Arrestin_N PF00339.29 KXS17512.1 - 0.00016 21.7 0.0 0.022 14.8 0.0 2.7 3 0 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain Spo0M PF07070.11 KXS17512.1 - 0.0023 17.5 0.0 0.18 11.3 0.0 2.2 2 0 0 2 2 2 2 SpoOM protein Swi3 PF07962.12 KXS17513.1 - 9.4e-24 83.2 0.1 1.4e-23 82.7 0.1 1.2 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 ABC2_membrane PF01061.24 KXS17515.1 - 1.4e-27 96.5 19.0 1.4e-27 96.5 19.0 1.5 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 KXS17515.1 - 9.7e-24 84.4 0.0 1.5e-23 83.9 0.0 1.3 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 KXS17515.1 - 7.6e-05 22.7 0.1 0.0021 18.0 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase Rad17 PF03215.15 KXS17515.1 - 0.001 19.0 0.0 0.0019 18.1 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_21 PF13304.6 KXS17515.1 - 0.0011 18.9 0.2 0.9 9.3 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KXS17515.1 - 0.0012 18.5 0.1 0.0026 17.4 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 KXS17515.1 - 0.0093 15.4 0.1 0.14 11.6 0.1 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KXS17515.1 - 0.019 15.2 0.0 0.039 14.2 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KXS17515.1 - 0.026 14.9 0.1 0.065 13.6 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 KXS17515.1 - 0.11 12.1 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 KXS17515.1 - 0.11 11.5 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_18 PF13238.6 KXS17515.1 - 0.14 12.7 0.0 0.28 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KXS17515.1 - 0.18 11.5 0.2 0.4 10.4 0.0 1.6 2 0 0 2 2 2 0 AAA domain NmrA PF05368.13 KXS17516.1 - 6.8e-46 156.7 0.0 7.3e-46 156.6 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXS17516.1 - 1.5e-20 73.9 0.3 2.7e-20 73.0 0.3 1.4 2 0 0 2 2 2 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KXS17516.1 - 9.1e-06 24.9 0.2 2e-05 23.8 0.2 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KXS17516.1 - 0.0001 21.9 0.1 0.00025 20.6 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1949 PF09186.11 KXS17516.1 - 0.096 12.6 0.1 0.22 11.4 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1949) GDP_Man_Dehyd PF16363.5 KXS17516.1 - 0.12 11.7 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase TrkA_N PF02254.18 KXS17516.1 - 0.13 12.5 0.0 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain Fer2_4 PF13510.6 KXS17516.1 - 0.19 11.8 0.5 0.73 9.9 0.0 2.0 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain Nitro_FeMo-Co PF02579.17 KXS17516.1 - 0.29 11.5 1.8 1.4 9.3 0.1 2.4 3 0 0 3 3 3 0 Dinitrogenase iron-molybdenum cofactor NmrA PF05368.13 KXS17517.1 - 1.9e-48 165.1 0.0 2.3e-48 164.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXS17517.1 - 5.1e-19 68.9 0.2 8.2e-19 68.2 0.2 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KXS17517.1 - 4.7e-05 23.0 0.1 0.00019 21.0 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXS17517.1 - 5.5e-05 22.3 0.2 0.00014 21.0 0.2 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.20 KXS17517.1 - 0.06 13.5 0.2 0.57 10.3 0.2 2.2 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus GDP_Man_Dehyd PF16363.5 KXS17517.1 - 0.072 12.5 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase TrkA_N PF02254.18 KXS17517.1 - 0.074 13.3 0.1 0.12 12.6 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain Nitro_FeMo-Co PF02579.17 KXS17517.1 - 0.11 12.8 1.5 0.17 12.2 0.1 2.0 3 0 0 3 3 3 0 Dinitrogenase iron-molybdenum cofactor DUF1949 PF09186.11 KXS17517.1 - 0.13 12.2 0.1 0.5 10.3 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1949) NmrA PF05368.13 KXS17518.1 - 3.3e-46 157.7 0.0 4e-46 157.4 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXS17518.1 - 3.8e-17 62.8 0.1 2.7e-16 60.0 0.1 2.0 1 1 1 2 2 2 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KXS17518.1 - 0.00055 19.0 0.1 0.0013 17.8 0.1 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KXS17518.1 - 0.00092 18.7 0.1 0.004 16.7 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Nitro_FeMo-Co PF02579.17 KXS17518.1 - 0.092 13.1 0.3 0.21 12.0 0.1 1.7 2 0 0 2 2 2 0 Dinitrogenase iron-molybdenum cofactor TrkA_N PF02254.18 KXS17518.1 - 0.12 12.6 0.0 0.19 12.0 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain RNF220 PF15926.5 KXS17519.1 - 8.2e-12 45.3 0.8 8.2e-12 45.3 0.8 2.5 3 0 0 3 3 3 1 E3 ubiquitin-protein ligase RNF220 zf-C3HC4_3 PF13920.6 KXS17519.1 - 1.6e-07 31.1 6.8 2.6e-07 30.4 6.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KXS17519.1 - 1.6e-06 27.8 6.7 2.9e-06 27.1 6.7 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 KXS17519.1 - 5.9e-06 26.0 9.3 9.8e-06 25.3 9.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXS17519.1 - 7.6e-05 22.5 7.4 0.00012 21.9 7.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXS17519.1 - 9.1e-05 22.7 9.6 0.00015 22.0 9.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KXS17519.1 - 0.0024 17.8 6.0 0.0043 17.0 6.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KXS17519.1 - 0.025 14.6 5.7 0.025 14.6 5.7 2.2 1 1 1 2 2 2 0 RING-type zinc-finger zf-RING_10 PF16685.5 KXS17519.1 - 0.077 13.1 8.2 0.13 12.4 8.2 1.3 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_4 PF14570.6 KXS17519.1 - 0.26 11.1 6.8 0.48 10.3 6.8 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 KXS17519.1 - 1.7 9.0 6.2 3.6 8.0 6.2 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 KXS17519.1 - 8.9 6.6 7.9 26 5.1 8.1 1.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING NAP PF00956.18 KXS17520.1 - 3.2e-10 39.6 0.7 4.8e-10 39.1 0.2 1.6 1 1 0 1 1 1 1 Nucleosome assembly protein (NAP) Voldacs PF03517.13 KXS17520.1 - 0.0066 16.6 2.9 0.011 15.8 2.9 1.4 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling MCM_lid PF17855.1 KXS17523.1 - 0.0021 18.5 0.3 0.0029 18.0 0.3 1.2 1 0 0 1 1 1 1 MCM AAA-lid domain Methyltransf_28 PF02636.17 KXS17525.1 - 2.8e-70 236.9 0.0 4e-70 236.4 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Haspin_kinase PF12330.8 KXS17525.1 - 0.16 10.9 0.0 0.21 10.5 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain WD40 PF00400.32 KXS17526.1 - 1.8e-05 25.4 2.3 0.14 13.0 0.1 3.5 4 0 0 4 4 4 2 WD domain, G-beta repeat Sec6 PF06046.13 KXS17527.1 - 1.8e-124 416.2 0.6 1.8e-124 416.2 0.6 1.4 2 0 0 2 2 2 1 Exocyst complex component Sec6 Vps53_N PF04100.12 KXS17527.1 - 4.4e-07 29.2 2.5 4.4e-07 29.2 2.5 2.0 2 0 0 2 2 2 1 Vps53-like, N-terminal PCRF PF03462.18 KXS17527.1 - 0.035 14.0 0.7 0.13 12.1 0.1 2.4 2 0 0 2 2 2 0 PCRF domain RIH_assoc PF08454.11 KXS17527.1 - 2.5 8.0 5.5 6.1 6.8 4.5 2.2 2 1 0 2 2 2 0 RyR and IP3R Homology associated TFIIIC_delta PF12657.7 KXS17529.1 - 1.4e-08 34.9 0.0 3.2e-08 33.7 0.0 1.5 1 1 0 1 1 1 1 Transcription factor IIIC subunit delta N-term PB1 PF00564.24 KXS17530.1 - 1.9e-09 37.4 0.1 3.3e-09 36.6 0.1 1.4 1 0 0 1 1 1 1 PB1 domain Bromodomain PF00439.25 KXS17531.1 - 2.5e-45 152.4 0.0 3.1e-21 75.2 0.0 2.9 3 0 0 3 3 3 2 Bromodomain BET PF17035.5 KXS17531.1 - 1.6e-18 66.6 0.1 4.2e-18 65.3 0.1 1.8 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation YL1 PF05764.13 KXS17531.1 - 0.00058 20.1 16.6 0.00058 20.1 16.6 3.2 3 1 1 4 4 4 1 YL1 nuclear protein EMP24_GP25L PF01105.24 KXS17531.1 - 3.4 7.6 8.3 4.3 7.2 4.5 2.4 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD DUF4207 PF13904.6 KXS17531.1 - 3.7 7.2 33.7 0.019 14.7 13.8 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4207) LegC3_N PF18654.1 KXS17531.1 - 5.2 6.2 22.2 0.3 10.3 8.2 3.3 4 0 0 4 4 4 0 LegC3 N-terminal coiled-coil domain zf-CCCH PF00642.24 KXS17532.1 - 5e-13 48.6 17.5 8.1e-07 28.8 2.8 2.6 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.22 KXS17532.1 - 8.6e-07 28.7 0.1 1.6e-06 27.8 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Collagen PF01391.18 KXS17532.1 - 1.9e-05 24.3 16.6 0.00041 20.0 4.4 2.6 2 1 0 2 2 2 2 Collagen triple helix repeat (20 copies) Torus PF16131.5 KXS17532.1 - 0.0012 19.6 3.2 0.38 11.5 0.2 2.6 2 0 0 2 2 2 2 Torus domain zf_CCCH_4 PF18345.1 KXS17532.1 - 0.0027 17.7 16.8 0.023 14.8 2.9 2.8 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_3 PF15663.5 KXS17532.1 - 0.0043 17.3 2.9 0.37 11.0 0.1 2.3 2 0 0 2 2 2 2 Zinc-finger containing family Nup35_RRM_2 PF14605.6 KXS17532.1 - 0.18 11.8 0.1 0.34 10.9 0.1 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Tmemb_185A PF10269.9 KXS17533.1 - 0.28 10.8 1.1 0.42 10.3 1.1 1.1 1 0 0 1 1 1 0 Transmembrane Fragile-X-F protein Mhr1 PF12829.7 KXS17534.1 - 0.00012 22.1 0.0 0.00022 21.3 0.0 1.5 1 0 0 1 1 1 1 Transcriptional regulation of mitochondrial recombination fn3 PF00041.21 KXS17535.1 - 7e-09 35.9 0.0 0.00013 22.3 0.1 2.6 2 1 0 2 2 2 2 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 KXS17535.1 - 0.00019 21.9 0.1 0.068 13.7 0.1 2.5 2 0 0 2 2 2 2 Purple acid Phosphatase, N-terminal domain IFT57 PF10498.9 KXS17536.1 - 1.9e-113 379.2 0.0 2.1e-113 379.0 0.0 1.0 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 Spc7 PF08317.11 KXS17536.1 - 0.00073 18.5 2.1 0.0012 17.8 2.1 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein FPP PF05911.11 KXS17536.1 - 0.0089 14.3 0.5 0.01 14.1 0.5 1.1 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil Lebercilin PF15619.6 KXS17536.1 - 0.014 15.1 1.2 0.12 12.1 0.1 1.9 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease WEMBL PF05701.11 KXS17536.1 - 0.015 14.0 1.7 0.023 13.4 1.7 1.3 1 0 0 1 1 1 0 Weak chloroplast movement under blue light Exonuc_VII_L PF02601.15 KXS17536.1 - 0.018 14.6 1.0 0.027 14.1 1.0 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Rootletin PF15035.6 KXS17536.1 - 0.02 14.9 2.6 0.059 13.4 2.4 1.8 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion GAS PF13851.6 KXS17536.1 - 0.02 14.2 1.8 0.042 13.2 1.8 1.6 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding COG2 PF06148.11 KXS17536.1 - 0.022 14.9 2.4 2.6 8.1 0.3 2.3 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Occludin_ELL PF07303.13 KXS17536.1 - 0.031 15.0 0.5 0.38 11.5 0.0 2.4 1 1 1 2 2 2 0 Occludin homology domain MscS_porin PF12795.7 KXS17536.1 - 0.032 13.8 2.2 0.19 11.2 2.2 1.9 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain BicD PF09730.9 KXS17536.1 - 0.044 12.2 2.8 0.058 11.8 2.2 1.3 1 1 0 1 1 1 0 Microtubule-associated protein Bicaudal-D Arfaptin PF06456.13 KXS17536.1 - 0.046 13.3 0.3 0.076 12.6 0.3 1.3 1 0 0 1 1 1 0 Arfaptin-like domain CALCOCO1 PF07888.11 KXS17536.1 - 0.05 12.5 1.0 0.073 11.9 1.0 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like EzrA PF06160.12 KXS17536.1 - 0.05 11.8 2.9 0.091 10.9 2.2 1.6 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA NPV_P10 PF05531.12 KXS17536.1 - 0.051 14.0 3.9 0.49 10.9 0.2 3.2 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.12 KXS17536.1 - 0.055 13.5 4.9 0.61 10.1 0.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) CENP-F_leu_zip PF10473.9 KXS17536.1 - 0.064 13.3 1.7 1.8 8.6 0.1 2.1 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMPIT PF07851.13 KXS17536.1 - 0.065 12.5 0.9 0.1 11.8 0.9 1.4 1 0 0 1 1 1 0 TMPIT-like protein DUF16 PF01519.16 KXS17536.1 - 0.081 13.4 3.1 0.11 13.0 0.6 2.5 3 0 0 3 3 2 0 Protein of unknown function DUF16 Baculo_PEP_C PF04513.12 KXS17536.1 - 0.1 12.6 1.9 0.35 10.9 1.9 1.9 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF148 PF02520.17 KXS17536.1 - 0.12 12.4 2.3 0.29 11.3 1.4 2.0 1 1 1 2 2 2 0 Domain of unknown function DUF148 TMF_DNA_bd PF12329.8 KXS17536.1 - 0.15 12.1 2.4 1 9.4 0.0 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding RasGAP_C PF03836.15 KXS17536.1 - 0.21 11.7 2.4 8.8 6.5 2.2 2.2 1 1 1 2 2 2 0 RasGAP C-terminus DUF4200 PF13863.6 KXS17536.1 - 0.23 11.8 3.4 1.2 9.6 0.5 2.5 3 0 0 3 3 2 0 Domain of unknown function (DUF4200) Prominin PF05478.11 KXS17536.1 - 0.23 9.3 1.5 0.33 8.9 1.5 1.1 1 0 0 1 1 1 0 Prominin Filament PF00038.21 KXS17536.1 - 0.24 11.0 3.1 0.66 9.5 3.1 1.7 1 1 0 1 1 1 0 Intermediate filament protein Fez1 PF06818.15 KXS17536.1 - 0.25 11.8 2.2 0.88 10.0 2.2 1.8 1 1 0 1 1 1 0 Fez1 HrpB7 PF09486.10 KXS17536.1 - 0.32 11.4 2.5 2.3 8.6 0.9 2.7 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) TPR_MLP1_2 PF07926.12 KXS17536.1 - 2.6 8.1 6.3 6 6.9 3.1 2.7 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein RFC1 PF08519.12 KXS17538.1 - 1.6e-45 155.1 0.0 4.4e-44 150.4 0.0 2.4 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain AAA PF00004.29 KXS17538.1 - 3.3e-14 53.4 0.1 1.2e-13 51.6 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) BRCT PF00533.26 KXS17538.1 - 9.3e-14 51.6 0.0 6.6e-13 48.8 0.0 2.4 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Rad17 PF03215.15 KXS17538.1 - 1.5e-08 34.8 0.1 3.1e-07 30.5 0.0 2.3 1 1 1 2 2 2 1 Rad17 P-loop domain NTPase_1 PF03266.15 KXS17538.1 - 6.4e-05 22.9 0.1 0.093 12.6 0.0 3.4 3 0 0 3 3 3 1 NTPase PTCB-BRCT PF12738.7 KXS17538.1 - 0.00012 22.0 0.0 0.00037 20.4 0.0 1.9 1 0 0 1 1 1 1 twin BRCT domain RuvB_N PF05496.12 KXS17538.1 - 0.00014 21.7 0.0 0.00038 20.2 0.0 1.7 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KXS17538.1 - 0.00015 22.0 0.0 0.0006 20.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KXS17538.1 - 0.0032 17.2 0.0 0.01 15.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KXS17538.1 - 0.0064 17.0 0.0 0.017 15.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KXS17538.1 - 0.0097 16.3 0.0 0.024 15.0 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.22 KXS17538.1 - 0.015 15.7 0.0 0.57 10.6 0.0 2.6 1 1 0 1 1 1 0 RNA helicase AAA_14 PF13173.6 KXS17538.1 - 0.018 15.1 0.0 0.085 12.9 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KXS17538.1 - 0.023 14.9 0.0 0.056 13.6 0.0 1.8 1 1 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.6 KXS17538.1 - 0.042 14.0 0.7 1.5 8.9 0.0 2.9 1 1 0 2 2 2 0 Sigma-54 interaction domain TniB PF05621.11 KXS17538.1 - 0.049 13.0 0.0 0.15 11.4 0.0 1.8 1 1 0 1 1 1 0 Bacterial TniB protein TFIIE_alpha PF02002.17 KXS17538.1 - 0.067 13.1 0.4 0.58 10.1 0.0 2.3 2 0 0 2 2 2 0 TFIIE alpha subunit TIP49 PF06068.13 KXS17538.1 - 0.074 12.2 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain NACHT PF05729.12 KXS17538.1 - 0.075 12.9 0.0 0.69 9.8 0.0 2.3 1 1 0 1 1 1 0 NACHT domain DNA_pol3_delta PF06144.13 KXS17538.1 - 0.13 12.1 0.0 0.3 10.8 0.0 1.6 1 0 0 1 1 1 0 DNA polymerase III, delta subunit BRCT_2 PF16589.5 KXS17538.1 - 0.15 12.5 0.1 0.4 11.1 0.1 1.7 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain T2SSE PF00437.20 KXS17538.1 - 0.15 11.1 0.0 0.31 10.1 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein CD99L2 PF12301.8 KXS17538.1 - 2.7 8.3 8.2 19 5.5 2.9 2.2 2 0 0 2 2 2 0 CD99 antigen like protein 2 WD40 PF00400.32 KXS17539.1 - 4.5e-14 52.6 7.9 0.00032 21.4 0.0 6.8 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXS17539.1 - 9.5e-08 32.2 0.1 0.093 13.0 0.0 4.7 3 1 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain SRA1 PF07304.11 KXS17539.1 - 0.0016 18.2 0.0 0.0016 18.2 0.0 2.4 2 1 0 2 2 2 1 Steroid receptor RNA activator (SRA1) UBA_4 PF14555.6 KXS17539.1 - 0.0045 16.8 0.0 0.011 15.6 0.0 1.7 1 0 0 1 1 1 1 UBA-like domain Sec16_C PF12931.7 KXS17539.1 - 0.0058 16.3 0.0 0.012 15.3 0.0 1.5 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 Diphthamide_syn PF01866.17 KXS17540.1 - 1.1e-67 228.7 0.0 2.5e-52 178.2 0.0 2.1 2 0 0 2 2 2 2 Putative diphthamide synthesis protein TruB_N PF01509.18 KXS17541.1 - 5.4e-42 143.7 0.0 8.1e-42 143.1 0.0 1.2 1 0 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 KXS17541.1 - 2e-07 31.0 0.1 4e-07 30.1 0.1 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain UBA2_C PF16195.5 KXS17541.1 - 0.055 14.1 0.1 0.11 13.2 0.1 1.4 1 0 0 1 1 1 0 SUMO-activating enzyme subunit 2 C-terminus Mito_carr PF00153.27 KXS17542.1 - 1.2e-60 201.5 3.5 9.9e-20 70.3 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Pkinase_Tyr PF07714.17 KXS17543.1 - 1.1e-33 116.6 0.0 2e-33 115.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXS17543.1 - 2.9e-23 82.6 1.2 4.5e-23 82.0 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Kdo PF06293.14 KXS17543.1 - 0.0011 18.3 0.2 0.0053 16.1 0.0 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KXS17543.1 - 0.0085 15.4 0.0 0.017 14.4 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Myb_DNA-bind_4 PF13837.6 KXS17543.1 - 0.013 15.9 1.1 0.03 14.7 1.1 1.6 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain SesA PF17107.5 KXS17543.1 - 0.014 15.6 2.9 0.21 11.8 0.0 3.0 2 1 1 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases APH PF01636.23 KXS17543.1 - 0.11 12.4 0.0 0.9 9.4 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family G_glu_transpept PF01019.21 KXS17545.1 - 8.8e-147 489.9 0.0 1e-146 489.7 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase AA_permease_2 PF13520.6 KXS17546.1 - 1.1e-14 54.1 44.9 1.6e-14 53.6 44.9 1.2 1 0 0 1 1 1 1 Amino acid permease DUF3017 PF11222.8 KXS17546.1 - 6.8 7.0 10.4 0.66 10.3 2.3 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3017) TRAPPC10 PF12584.8 KXS17548.1 - 1.2e-09 38.0 0.0 3e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 Foie-gras_1 PF11817.8 KXS17548.1 - 0.014 15.0 0.4 0.025 14.2 0.4 1.4 1 0 0 1 1 1 0 Foie gras liver health family 1 HECT PF00632.25 KXS17549.1 - 3e-88 296.3 0.0 4.4e-88 295.7 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) CDP-OH_P_transf PF01066.21 KXS17550.1 - 5e-15 56.0 0.6 5e-15 56.0 0.6 1.8 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase IBN_N PF03810.19 KXS17551.1 - 2.3e-06 27.4 0.2 8.1e-06 25.7 0.2 2.0 1 0 0 1 1 1 1 Importin-beta N-terminal domain CRM1_C PF08767.11 KXS17551.1 - 0.021 14.0 0.6 0.072 12.2 0.2 2.1 2 0 0 2 2 2 0 CRM1 C terminal DUF1751 PF08551.10 KXS17552.1 - 1.2e-20 73.9 5.7 1.2e-20 73.9 5.7 1.8 2 0 0 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.22 KXS17552.1 - 0.019 15.0 13.9 0.032 14.2 13.9 1.3 1 0 0 1 1 1 0 Rhomboid family Rap_GAP PF02145.15 KXS17553.1 - 2.4e-49 167.4 0.0 3.7e-49 166.8 0.0 1.3 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.16 KXS17553.1 - 4.2e-28 98.5 0.7 1.1e-24 87.2 0.0 2.1 2 0 0 2 2 2 2 Tuberin Glyco_trans_1_4 PF13692.6 KXS17555.1 - 0.0065 16.9 0.0 0.023 15.1 0.0 1.9 1 1 0 1 1 1 1 Glycosyl transferases group 1 SBDS_C PF09377.10 KXS17556.1 - 1e-35 122.2 0.0 1.6e-35 121.6 0.0 1.3 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.18 KXS17556.1 - 1.7e-32 111.3 0.6 2.9e-32 110.6 0.2 1.6 2 0 0 2 2 2 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein SLS PF14611.6 KXS17556.1 - 0.0044 16.9 0.1 0.1 12.4 0.0 2.1 2 0 0 2 2 2 1 Mitochondrial inner-membrane-bound regulator FAM184 PF15665.5 KXS17557.1 - 5.7e-08 32.8 20.9 5.7e-08 32.8 20.9 8.7 1 1 5 7 7 7 2 Family with sequence similarity 184, A and B ABC_tran_CTD PF16326.5 KXS17557.1 - 0.00027 21.1 4.0 0.00027 21.1 4.0 13.3 8 5 2 12 12 12 1 ABC transporter C-terminal domain DUF4337 PF14235.6 KXS17557.1 - 0.0042 17.2 1.5 0.0042 17.2 1.5 9.6 1 1 7 10 10 10 1 Domain of unknown function (DUF4337) ATG16 PF08614.11 KXS17557.1 - 0.008 16.4 20.6 0.008 16.4 20.6 10.1 1 1 6 8 8 8 3 Autophagy protein 16 (ATG16) Fib_alpha PF08702.10 KXS17557.1 - 0.64 10.2 81.3 0.63 10.2 6.3 9.4 2 2 7 10 10 10 0 Fibrinogen alpha/beta chain family ATP-synt_F6 PF05511.11 KXS17557.1 - 1.2 9.6 4.5 3.7 8.0 0.8 3.7 2 1 0 2 2 2 0 Mitochondrial ATP synthase coupling factor 6 Baculo_PEP_C PF04513.12 KXS17557.1 - 6.2 6.9 52.6 0.27 11.3 2.1 9.2 4 2 6 11 11 11 0 Baculovirus polyhedron envelope protein, PEP, C terminus FHA_2 PF17913.1 KXS17558.1 - 0.00015 21.9 0.0 0.00024 21.3 0.0 1.2 1 0 0 1 1 1 1 FHA domain HMG_box PF00505.19 KXS17558.1 - 0.0024 18.3 0.0 0.0024 18.3 0.0 1.6 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KXS17558.1 - 0.2 12.3 1.5 0.21 12.2 0.0 1.8 2 0 0 2 2 2 0 HMG-box domain Pns11_12 PF17464.2 KXS17558.1 - 4.8 6.8 8.4 1.3 8.7 2.7 2.3 2 0 0 2 2 2 0 Non-structural protein 11 and 12 His_Phos_2 PF00328.22 KXS17559.1 - 3.1e-75 253.9 0.0 3.8e-75 253.6 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 KXS17559.1 - 6.9e-35 119.1 0.0 1.7e-34 117.8 0.0 1.7 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 KXS17559.1 - 0.0039 16.8 0.0 0.0074 15.9 0.0 1.3 1 0 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.14 KXS17559.1 - 0.2 11.7 0.3 0.73 9.9 0.0 2.0 2 1 0 2 2 2 0 ATP-grasp domain Prefoldin_2 PF01920.20 KXS17560.1 - 3e-18 65.7 12.8 3.9e-18 65.3 12.8 1.2 1 0 0 1 1 1 1 Prefoldin subunit DUF16 PF01519.16 KXS17560.1 - 0.018 15.5 4.6 0.018 15.5 4.6 2.0 1 1 1 2 2 2 0 Protein of unknown function DUF16 Surfac_D-trimer PF09006.11 KXS17560.1 - 0.07 13.0 0.3 0.77 9.7 0.1 2.3 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation Fib_alpha PF08702.10 KXS17560.1 - 0.078 13.2 10.7 0.25 11.5 10.7 1.7 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Rx_N PF18052.1 KXS17560.1 - 0.61 10.4 7.0 6.1 7.2 7.0 2.3 1 1 0 1 1 1 0 Rx N-terminal domain USP8_interact PF08941.10 KXS17560.1 - 4.6 7.0 6.6 0.86 9.4 0.9 2.0 1 1 1 2 2 2 0 USP8 interacting MRP-S33 PF08293.11 KXS17561.1 - 2.6e-11 43.6 0.0 3.4e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 TRAPP PF04051.16 KXS17562.1 - 7.4e-44 149.0 0.0 9.1e-44 148.7 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component NDUFB10 PF10249.9 KXS17563.1 - 8.9e-06 26.2 0.1 9.1e-06 26.2 0.1 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 V-ATPase_G PF03179.15 KXS17564.1 - 3.3e-30 104.7 12.9 3.8e-30 104.5 12.9 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit vATP-synt_E PF01991.18 KXS17564.1 - 8.9e-05 22.0 7.8 0.00011 21.7 7.8 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit ATP-synt_B PF00430.18 KXS17564.1 - 0.014 15.5 11.1 0.014 15.5 11.1 2.0 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) DUF4375 PF14300.6 KXS17564.1 - 0.025 14.8 2.9 0.038 14.3 1.6 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4375) MtaB PF12176.8 KXS17564.1 - 0.053 12.3 3.5 0.061 12.1 3.5 1.0 1 0 0 1 1 1 0 Methanol-cobalamin methyltransferase B subunit MPM1 PF17234.2 KXS17564.1 - 0.079 13.2 1.3 0.099 12.9 1.3 1.1 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 RuvC_III PF18541.1 KXS17564.1 - 0.15 12.0 3.1 0.2 11.6 3.1 1.1 1 0 0 1 1 1 0 RuvC endonuclease subdomain 3 PEP-utilisers_N PF05524.13 KXS17564.1 - 0.21 11.8 4.6 0.28 11.4 4.6 1.5 1 1 0 1 1 1 0 PEP-utilising enzyme, N-terminal DUF5082 PF16888.5 KXS17564.1 - 0.63 10.3 5.4 1.3 9.3 5.4 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) Seryl_tRNA_N PF02403.22 KXS17564.1 - 0.86 9.9 8.2 1.8 8.8 7.8 1.8 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Ribosomal_L3 PF00297.22 KXS17565.1 - 5.4e-188 624.5 8.9 6.1e-188 624.3 8.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 SCAI PF12070.8 KXS17566.1 - 3.5e-185 616.9 0.1 4.3e-185 616.6 0.1 1.1 1 0 0 1 1 1 1 Protein SCAI RNA_pol_Rpb5_C PF01191.19 KXS17567.1 - 1.3e-33 114.7 0.3 2.8e-33 113.6 0.3 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 KXS17567.1 - 6.9e-23 81.0 0.4 1.1e-22 80.3 0.4 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.12 KXS17567.1 - 0.01 15.9 0.1 0.015 15.3 0.1 1.4 1 1 0 1 1 1 0 Restriction endonuclease NPIP PF06409.11 KXS17567.1 - 0.036 13.1 0.0 0.048 12.7 0.0 1.2 1 0 0 1 1 1 0 Nuclear pore complex interacting protein (NPIP) Baculo_F PF12259.8 KXS17568.1 - 0.1 11.1 1.1 0.14 10.7 1.1 1.2 1 0 0 1 1 1 0 Baculovirus F protein Alpha-2-MRAP_C PF06401.11 KXS17568.1 - 0.11 12.5 4.1 0.66 9.9 5.5 1.6 2 0 0 2 2 2 0 Alpha-2-macroglobulin RAP, C-terminal domain DHR10 PF18595.1 KXS17568.1 - 2.3 8.3 23.4 2.2 8.4 12.1 3.6 4 0 0 4 4 4 0 Designed helical repeat protein 10 domain Methyltransf_5 PF01795.19 KXS17570.1 - 8.2e-85 285.0 0.0 9.6e-85 284.8 0.0 1.0 1 0 0 1 1 1 1 MraW methylase family Methyltransf_25 PF13649.6 KXS17570.1 - 0.0026 18.4 0.0 0.0073 17.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXS17570.1 - 0.088 12.6 0.0 0.51 10.1 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Methyltr_RsmB-F PF01189.17 KXS17570.1 - 0.16 11.6 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F HHH_3 PF12836.7 KXS17570.1 - 0.18 12.1 0.0 0.42 10.9 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif Peptidase_C15 PF01470.17 KXS17571.1 - 1.4e-07 31.9 0.0 0.011 15.9 0.0 2.2 2 0 0 2 2 2 2 Pyroglutamyl peptidase LRR_9 PF14580.6 KXS17572.1 - 2.5e-18 66.2 3.0 3.3e-14 52.8 1.1 2.4 2 0 0 2 2 2 2 Leucine-rich repeat LRR_4 PF12799.7 KXS17572.1 - 1.7e-08 34.6 12.2 0.0033 17.8 0.4 4.1 2 2 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXS17572.1 - 3.9e-05 23.3 11.9 0.0094 15.7 2.6 3.5 3 1 1 4 4 4 3 Leucine rich repeat LRR_6 PF13516.6 KXS17572.1 - 0.00043 20.1 1.5 3.3 8.0 0.0 4.1 4 0 0 4 4 4 2 Leucine Rich repeat LRR_1 PF00560.33 KXS17572.1 - 0.082 13.5 6.7 10 7.1 0.0 4.7 4 0 0 4 4 4 0 Leucine Rich Repeat TPR_1 PF00515.28 KXS17573.1 - 1.7e-18 65.6 2.2 0.0047 16.7 0.0 7.0 7 0 0 7 7 6 5 Tetratricopeptide repeat TPR_2 PF07719.17 KXS17573.1 - 1e-17 62.7 9.8 0.0061 16.6 0.0 8.8 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_8 PF13181.6 KXS17573.1 - 1.1e-15 56.4 2.3 0.24 11.7 0.0 7.5 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_9 PF13371.6 KXS17573.1 - 5.2e-13 48.9 20.3 3.2e-05 24.0 1.8 6.0 4 1 2 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.6 KXS17573.1 - 2.9e-10 39.7 6.0 0.29 10.9 0.0 7.6 7 1 1 8 8 8 3 TPR repeat TPR_16 PF13432.6 KXS17573.1 - 3.3e-07 30.8 18.0 0.71 10.6 0.1 6.1 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_12 PF13424.6 KXS17573.1 - 1.2e-06 28.7 10.7 5.4 7.4 0.0 5.8 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 KXS17573.1 - 3e-06 26.9 1.7 1.6 8.9 0.0 5.8 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 KXS17573.1 - 4e-06 27.2 7.0 0.21 12.1 0.1 5.2 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 KXS17573.1 - 4.2e-06 26.8 2.4 0.63 10.6 0.0 6.1 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_14 PF13428.6 KXS17573.1 - 7e-05 23.3 18.1 5.4 8.1 0.0 7.9 6 2 2 8 8 8 2 Tetratricopeptide repeat TPR_15 PF13429.6 KXS17573.1 - 0.00017 20.9 3.8 2.3 7.4 0.1 4.5 4 1 0 4 4 4 2 Tetratricopeptide repeat SPO22 PF08631.10 KXS17573.1 - 0.016 14.7 0.0 0.12 11.9 0.0 2.4 2 1 0 2 2 2 0 Meiosis protein SPO22/ZIP4 like Coatomer_E PF04733.14 KXS17573.1 - 0.14 11.5 0.0 0.27 10.6 0.0 1.4 1 0 0 1 1 1 0 Coatomer epsilon subunit HPP PF04982.13 KXS17574.1 - 3.2e-33 114.5 0.7 3.2e-33 114.5 0.7 1.5 2 0 0 2 2 2 1 HPP family Flavi_glycoprot PF00869.20 KXS17574.1 - 0.19 10.9 0.2 0.33 10.1 0.1 1.5 1 1 0 1 1 1 0 Flavivirus glycoprotein, central and dimerisation domains ubiquitin PF00240.23 KXS17575.1 - 1.5e-13 50.3 0.0 2.2e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KXS17575.1 - 0.00018 21.2 0.0 0.00028 20.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 KXS17575.1 - 0.028 15.0 0.0 0.043 14.4 0.0 1.4 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Tugs PF17840.1 KXS17575.1 - 0.041 14.1 0.1 0.075 13.2 0.1 1.4 1 0 0 1 1 1 0 Tethering Ubl4a to BAGS domain Ubiquitin_4 PF18036.1 KXS17575.1 - 0.09 12.8 0.0 0.41 10.7 0.0 1.9 1 1 1 2 2 2 0 Ubiquitin-like domain Blt1_C PF17183.4 KXS17575.1 - 0.18 11.4 0.5 0.35 10.5 0.5 1.4 1 0 0 1 1 1 0 Get5 carboxyl domain Ribosomal_L22 PF00237.19 KXS17576.1 - 5.4e-44 148.6 0.4 5.4e-44 148.6 0.4 1.5 2 0 0 2 2 2 1 Ribosomal protein L22p/L17e Dynamin_N PF00350.23 KXS17577.1 - 2.1e-17 63.7 0.1 6.4e-17 62.1 0.0 1.9 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 KXS17577.1 - 4.1e-09 36.5 0.0 1.3e-08 34.9 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KXS17577.1 - 3.2e-05 23.5 0.0 0.0035 16.9 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain IIGP PF05049.13 KXS17577.1 - 0.014 14.5 0.0 0.024 13.7 0.0 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Roc PF08477.13 KXS17577.1 - 0.026 14.7 0.0 0.55 10.5 0.0 2.9 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 KXS17577.1 - 0.034 13.9 0.0 0.1 12.3 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AIG1 PF04548.16 KXS17577.1 - 0.059 12.7 0.0 0.31 10.3 0.0 2.0 2 0 0 2 2 2 0 AIG1 family TsaE PF02367.17 KXS17577.1 - 0.068 13.2 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ANAPC4_WD40 PF12894.7 KXS17578.1 - 4e-15 55.9 0.4 0.033 14.5 0.0 6.6 3 2 2 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KXS17578.1 - 2.8e-10 40.6 2.4 0.013 16.3 0.0 6.5 7 0 0 7 7 5 1 WD domain, G-beta repeat Clathrin PF00637.20 KXS17578.1 - 5.2e-08 32.9 20.9 0.016 15.1 0.0 9.7 8 3 4 12 12 12 2 Region in Clathrin and VPS eIF2A PF08662.11 KXS17578.1 - 6.8e-06 26.1 0.4 0.46 10.3 0.0 3.9 3 1 0 4 4 4 2 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.14 KXS17578.1 - 1.3e-05 24.4 7.7 0.63 9.0 0.0 6.2 4 1 1 6 6 6 2 Coatomer WD associated region Ge1_WD40 PF16529.5 KXS17578.1 - 3.6e-05 22.9 0.1 0.17 10.8 0.0 2.9 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein TPR_16 PF13432.6 KXS17578.1 - 5.4e-05 23.8 18.9 14 6.4 0.2 8.9 9 0 0 9 9 8 0 Tetratricopeptide repeat Nic96 PF04097.14 KXS17578.1 - 0.00054 18.5 0.4 0.24 9.8 0.1 2.7 2 0 0 2 2 2 2 Nup93/Nic96 ANAPC3 PF12895.7 KXS17578.1 - 0.00096 19.3 20.1 14 6.0 0.3 9.6 8 2 2 10 10 10 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 KXS17578.1 - 0.0035 17.0 1.9 5.5 6.8 0.0 4.7 4 0 0 4 4 4 1 TPR repeat PPR PF01535.20 KXS17578.1 - 0.0052 17.0 5.8 17 6.0 0.0 7.2 7 0 0 7 7 7 0 PPR repeat TPR_2 PF07719.17 KXS17578.1 - 0.014 15.4 23.2 4.5 7.6 0.2 9.9 11 0 0 11 11 10 0 Tetratricopeptide repeat TPR_8 PF13181.6 KXS17578.1 - 0.017 15.3 15.9 0.79 10.1 0.1 7.7 8 0 0 8 8 6 0 Tetratricopeptide repeat PQQ_2 PF13360.6 KXS17578.1 - 0.028 14.0 0.1 0.1 12.2 0.1 2.0 1 0 0 1 1 1 0 PQQ-like domain TPR_7 PF13176.6 KXS17578.1 - 0.06 13.4 14.8 5.2 7.3 0.0 8.4 10 0 0 10 10 8 0 Tetratricopeptide repeat Sec16_C PF12931.7 KXS17578.1 - 0.07 12.8 8.2 5.2 6.6 0.5 4.9 5 1 1 6 6 6 0 Sec23-binding domain of Sec16 TPR_1 PF00515.28 KXS17578.1 - 0.19 11.6 24.8 0.36 10.7 0.1 8.9 11 0 0 11 11 10 0 Tetratricopeptide repeat zf-RanBP PF00641.18 KXS17578.1 - 0.54 9.6 3.9 1.7 8.0 3.9 1.9 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others TPR_14 PF13428.6 KXS17578.1 - 3.3 8.8 28.0 44 5.3 0.0 11.2 12 2 1 14 14 10 0 Tetratricopeptide repeat RPN7 PF10602.9 KXS17578.1 - 5.9 6.6 14.5 7.6 6.2 1.1 4.8 5 1 0 6 6 6 0 26S proteasome subunit RPN7 zf-tcix PF14952.6 KXS17578.1 - 6.1 6.5 6.9 0.73 9.5 1.9 2.0 2 0 0 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding zf-ribbon_3 PF13248.6 KXS17578.1 - 6.7 6.3 6.7 26 4.4 0.1 2.6 2 0 0 2 2 2 0 zinc-ribbon domain DZR PF12773.7 KXS17578.1 - 8.5 6.5 12.0 44 4.2 12.0 2.2 1 1 0 1 1 1 0 Double zinc ribbon GAS PF13851.6 KXS17579.1 - 0.019 14.3 41.2 0.13 11.6 0.1 5.4 2 1 3 5 5 5 0 Growth-arrest specific micro-tubule binding DUF1515 PF07439.11 KXS17579.1 - 0.1 12.7 0.3 0.1 12.7 0.3 4.0 4 1 0 4 4 4 0 Protein of unknown function (DUF1515) Spc7 PF08317.11 KXS17579.1 - 9.8 4.9 50.3 5.5 5.8 15.3 4.3 2 1 2 4 4 4 0 Spc7 kinetochore protein MMR_HSR1 PF01926.23 KXS17580.1 - 2.7e-17 62.9 0.0 7.3e-17 61.5 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KXS17580.1 - 1.8e-07 30.8 0.0 1.1e-05 25.1 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KXS17580.1 - 2e-07 31.0 0.0 0.01 15.7 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase AIG1 PF04548.16 KXS17580.1 - 2e-05 24.0 0.0 3.5e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 AIG1 family IIGP PF05049.13 KXS17580.1 - 0.0014 17.7 0.0 0.0022 17.1 0.0 1.2 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) GTP_EFTU PF00009.27 KXS17580.1 - 0.0055 16.3 0.0 1.1 8.7 0.0 2.8 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 KXS17580.1 - 0.0062 16.6 0.5 3.2 7.8 0.1 2.6 1 1 1 2 2 2 2 Dynamin family AAA_16 PF13191.6 KXS17580.1 - 0.11 12.9 0.0 0.37 11.1 0.0 1.8 1 1 1 2 2 2 0 AAA ATPase domain SRPRB PF09439.10 KXS17580.1 - 0.13 11.7 0.0 5.6 6.3 0.0 2.4 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Exo84_C PF16528.5 KXS17582.1 - 3.4e-57 193.6 0.7 7.2e-57 192.5 0.7 1.6 1 0 0 1 1 1 1 Exocyst component 84 C-terminal Vps51 PF08700.11 KXS17582.1 - 3.5e-13 49.4 0.2 7.2e-13 48.4 0.2 1.6 1 0 0 1 1 1 1 Vps51/Vps67 COG2 PF06148.11 KXS17582.1 - 0.0036 17.4 0.1 0.012 15.7 0.1 1.9 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Sec5 PF15469.6 KXS17582.1 - 0.059 13.2 0.1 0.35 10.6 0.0 2.2 2 0 0 2 2 2 0 Exocyst complex component Sec5 GIT1_C PF12205.8 KXS17582.1 - 0.09 12.9 0.1 14 5.9 0.0 2.8 2 0 0 2 2 2 0 G protein-coupled receptor kinase-interacting protein 1 C term RRM_1 PF00076.22 KXS17583.1 - 1e-12 47.7 0.0 2.3e-12 46.5 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MMR_HSR1 PF01926.23 KXS17584.1 - 6.7e-16 58.4 0.0 1.5e-14 54.0 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KXS17584.1 - 4.4e-06 26.7 0.1 0.014 15.3 0.1 2.3 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 KXS17584.1 - 3.5e-05 23.4 0.0 0.00018 21.0 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B AIG1 PF04548.16 KXS17584.1 - 0.019 14.3 0.0 0.033 13.5 0.0 1.4 1 0 0 1 1 1 0 AIG1 family Dynamin_N PF00350.23 KXS17584.1 - 0.05 13.7 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 Dynamin family ANAPC_CDC26 PF10471.9 KXS17584.1 - 4.9 8.1 8.0 1.1 10.1 0.8 3.1 3 0 0 3 3 3 0 Anaphase-promoting complex APC subunit CDC26 Homeodomain PF00046.29 KXS17585.1 - 1.9e-18 66.1 5.6 3.7e-18 65.1 5.6 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KXS17585.1 - 0.012 15.5 0.6 0.03 14.2 0.6 1.7 1 0 0 1 1 1 0 Homeobox KN domain YdaS_antitoxin PF15943.5 KXS17585.1 - 0.067 13.1 0.1 0.15 12.0 0.1 1.5 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT DUF720 PF05302.11 KXS17585.1 - 0.77 9.6 6.1 1.5 8.6 6.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF720) MIF4G PF02854.19 KXS17587.1 - 9.9e-48 162.6 3.1 1.1e-47 162.4 3.1 1.0 1 0 0 1 1 1 1 MIF4G domain DEAD PF00270.29 KXS17588.1 - 7.6e-47 159.3 0.0 1.6e-46 158.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXS17588.1 - 2.2e-29 102.0 0.0 8.8e-28 96.9 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXS17588.1 - 7.6e-07 29.3 0.0 6.3e-06 26.3 0.0 2.3 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KXS17588.1 - 0.056 13.7 0.1 0.18 12.0 0.1 1.9 1 1 0 1 1 1 0 AAA domain IGPS PF00218.21 KXS17589.1 - 9.2e-90 300.2 0.1 1.5e-89 299.5 0.1 1.4 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase GATase PF00117.28 KXS17589.1 - 3.2e-46 157.5 0.0 4.9e-46 156.9 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I PRAI PF00697.22 KXS17589.1 - 1.6e-41 142.2 0.1 2.6e-37 128.5 0.0 2.3 2 0 0 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase Peptidase_C26 PF07722.13 KXS17589.1 - 3.6e-06 26.9 0.4 1.7e-05 24.7 0.4 2.0 1 1 0 1 1 1 1 Peptidase C26 FMN_dh PF01070.18 KXS17589.1 - 0.005 15.9 0.5 0.044 12.8 0.0 2.2 2 0 0 2 2 2 1 FMN-dependent dehydrogenase DHO_dh PF01180.21 KXS17589.1 - 0.021 14.0 0.0 0.043 13.0 0.0 1.4 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase Chorismate_bind PF00425.18 KXS17590.1 - 4.4e-97 324.7 0.0 1.1e-96 323.4 0.0 1.7 2 0 0 2 2 2 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 KXS17590.1 - 8.2e-33 113.6 0.0 2.4e-31 108.8 0.0 2.6 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region Voltage_CLC PF00654.20 KXS17591.1 - 3.8e-90 302.7 21.9 3.8e-90 302.7 21.9 1.8 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 KXS17591.1 - 1.2e-07 32.0 0.4 0.0034 17.8 0.1 2.5 2 0 0 2 2 2 2 CBS domain PQ-loop PF04193.14 KXS17592.1 - 1.2e-23 82.7 13.2 7.7e-13 48.0 1.1 2.6 3 0 0 3 3 3 2 PQ loop repeat ER_lumen_recept PF00810.18 KXS17592.1 - 0.034 15.0 1.9 0.057 14.3 1.9 1.3 1 0 0 1 1 1 0 ER lumen protein retaining receptor Phage_holin_8 PF16931.5 KXS17592.1 - 0.13 12.2 3.9 0.25 11.3 3.9 1.4 1 0 0 1 1 1 0 Putative phage holin ANAPC4_WD40 PF12894.7 KXS17593.1 - 9.8e-06 25.8 0.0 0.28 11.5 0.0 3.7 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KXS17593.1 - 0.032 15.1 0.7 6.1 7.9 0.0 3.8 3 0 0 3 3 3 0 WD domain, G-beta repeat PD40 PF07676.12 KXS17593.1 - 0.12 12.3 0.4 23 5.1 0.0 3.8 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Thiolase_N PF00108.23 KXS17594.1 - 8.2e-70 235.1 2.6 1.1e-69 234.7 2.6 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KXS17594.1 - 4.4e-43 145.9 0.2 1.5e-42 144.1 0.1 2.0 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KXS17594.1 - 9.6e-05 22.1 1.4 0.00071 19.2 1.6 2.2 2 1 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KXS17594.1 - 0.28 11.1 1.9 0.34 10.8 0.3 2.0 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Moricin PF06451.11 KXS17594.1 - 0.59 9.9 3.4 0.89 9.4 0.1 3.0 3 0 0 3 3 3 0 Moricin Glyco_hydro_16 PF00722.21 KXS17595.1 - 5.3e-16 58.6 3.1 7.6e-16 58.1 3.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DUF5585 PF17823.1 KXS17595.1 - 1.4 7.8 20.8 2 7.3 20.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5585) DUF3446 PF11928.8 KXS17596.1 - 0.27 11.6 10.4 1.6 9.1 1.7 2.3 2 0 0 2 2 2 0 Early growth response N-terminal domain Cyclin PF08613.11 KXS17596.1 - 1.3 9.3 0.0 1.3 9.3 0.0 2.5 2 1 1 3 3 3 0 Cyclin N2227 PF07942.12 KXS17597.1 - 2.8e-96 321.9 0.0 3.7e-96 321.5 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.6 KXS17597.1 - 0.00086 19.2 0.0 0.0019 18.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXS17597.1 - 0.01 16.6 0.0 0.07 13.9 0.0 2.5 2 1 0 2 2 2 0 Methyltransferase domain DUF2781 PF10914.8 KXS17598.1 - 6.2e-16 59.1 6.5 7.7e-16 58.8 6.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) SBF PF01758.16 KXS17598.1 - 0.15 11.7 3.1 0.28 10.8 1.5 2.0 1 1 1 2 2 2 0 Sodium Bile acid symporter family RRM_1 PF00076.22 KXS17599.1 - 1e-34 118.1 0.0 3.3e-16 58.8 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KXS17599.1 - 4.7e-12 45.9 0.1 0.00019 21.5 0.1 3.0 2 2 0 2 2 2 2 RNA recognition motif RL PF17797.1 KXS17599.1 - 0.083 12.8 0.0 7.2 6.6 0.0 2.3 2 0 0 2 2 2 0 RL domain Ion_trans PF00520.31 KXS17600.1 - 2.7e-16 59.6 2.9 3.5e-16 59.2 2.9 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 KXS17600.1 - 9.1e-11 41.6 7.9 2.2e-10 40.3 7.9 1.6 1 1 0 1 1 1 1 Ion channel DUF21 PF01595.20 KXS17600.1 - 0.022 14.5 0.4 0.036 13.8 0.4 1.3 1 0 0 1 1 1 0 Cyclin M transmembrane N-terminal domain IRK PF01007.20 KXS17600.1 - 0.039 13.8 0.8 0.06 13.2 0.8 1.2 1 0 0 1 1 1 0 Inward rectifier potassium channel transmembrane domain zf-C2H2 PF00096.26 KXS17602.1 - 0.00055 20.3 11.6 0.012 16.0 2.2 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXS17602.1 - 0.0039 17.9 10.2 0.054 14.4 1.5 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KXS17602.1 - 0.0081 16.4 0.3 0.017 15.4 0.3 1.5 1 0 0 1 1 1 1 C2H2-type zinc ribbon zf-C2H2_aberr PF17017.5 KXS17602.1 - 0.024 14.8 0.5 0.034 14.3 0.5 1.2 1 0 0 1 1 1 0 Aberrant zinc-finger FOXP-CC PF16159.5 KXS17602.1 - 0.028 15.1 0.1 0.055 14.1 0.1 1.5 1 0 0 1 1 1 0 FOXP coiled-coil domain Acetyltransf_1 PF00583.25 KXS17603.1 - 8e-12 45.4 0.0 8.4e-12 45.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXS17603.1 - 4.8e-09 36.5 0.0 5.7e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KXS17603.1 - 2.3e-08 34.0 0.0 2.6e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KXS17603.1 - 1.8e-05 24.8 0.0 2e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.7 KXS17603.1 - 0.0016 18.6 0.0 0.002 18.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KXS17603.1 - 0.0022 18.7 0.0 0.0024 18.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.7 KXS17603.1 - 0.0034 17.5 0.0 0.0034 17.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXS17603.1 - 0.026 14.5 0.0 0.034 14.1 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_16 PF05301.11 KXS17603.1 - 0.061 13.1 0.0 0.074 12.8 0.0 1.1 1 0 0 1 1 1 0 GNAT acetyltransferase, Mec-17 Ribosomal_S24e PF01282.19 KXS17604.1 - 1.7e-34 117.6 1.5 4.9e-34 116.1 1.5 1.8 1 1 0 1 1 1 1 Ribosomal protein S24e SPO22 PF08631.10 KXS17605.1 - 1.5e-21 77.1 2.2 1.5e-21 77.1 2.2 2.0 2 1 1 3 3 3 1 Meiosis protein SPO22/ZIP4 like RNA_pol_Rpb6 PF01192.22 KXS17605.1 - 0.19 11.6 1.2 0.34 10.9 0.1 2.1 2 0 0 2 2 2 0 RNA polymerase Rpb6 TPR_2 PF07719.17 KXS17605.1 - 0.63 10.3 16.9 0.37 11.0 0.3 5.9 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 KXS17605.1 - 2.9 8.3 9.8 45 4.6 0.0 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat Pyr_redox_2 PF07992.14 KXS17607.1 - 3.1e-15 56.2 0.0 5.2e-11 42.3 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXS17607.1 - 1.6e-13 50.6 0.0 1.2e-09 37.9 0.0 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXS17607.1 - 1.8e-09 37.6 0.1 0.0076 15.9 0.1 3.2 3 0 0 3 3 3 2 FAD dependent oxidoreductase FMO-like PF00743.19 KXS17607.1 - 1.4e-08 33.6 0.0 9.8e-06 24.3 0.0 2.5 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KXS17607.1 - 3.3e-08 33.6 0.0 1.4e-07 31.6 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KXS17607.1 - 9.2e-05 22.5 0.0 5.7 6.9 0.0 4.2 4 0 0 4 4 4 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 KXS17607.1 - 0.00016 20.9 0.1 0.15 11.2 0.0 2.7 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.22 KXS17607.1 - 0.00018 20.7 0.0 2.9 6.9 0.1 3.3 3 0 0 3 3 3 2 Glucose inhibited division protein A FAD_binding_2 PF00890.24 KXS17607.1 - 0.0042 16.2 0.1 0.0075 15.4 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KXS17607.1 - 0.013 14.2 0.5 0.57 8.8 0.6 2.6 3 0 0 3 3 3 0 HI0933-like protein Lycopene_cycl PF05834.12 KXS17607.1 - 0.024 13.7 0.0 4.9 6.1 0.0 2.6 3 0 0 3 3 3 0 Lycopene cyclase protein Shikimate_DH PF01488.20 KXS17607.1 - 0.18 11.9 0.0 0.45 10.6 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Ank_2 PF12796.7 KXS17608.1 - 2.8e-62 207.3 1.1 6.3e-10 39.5 0.0 8.4 5 1 3 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXS17608.1 - 1e-51 172.6 8.1 2e-08 34.6 0.1 10.7 8 3 3 11 11 11 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXS17608.1 - 7.1e-45 150.5 27.5 6.5e-08 32.7 0.4 11.8 8 4 5 13 13 13 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXS17608.1 - 2e-42 138.3 11.7 0.00095 19.5 0.0 14.8 15 0 0 15 15 15 10 Ankyrin repeat Ank PF00023.30 KXS17608.1 - 9.2e-37 123.9 33.4 0.0032 17.8 0.0 15.0 16 0 0 16 16 16 10 Ankyrin repeat DUF4287 PF14117.6 KXS17608.1 - 0.057 13.6 0.3 0.66 10.2 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4287) AhpC-TSA_2 PF13911.6 KXS17610.1 - 1.2e-12 47.9 0.0 1.5e-12 47.7 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme DUF3335 PF11814.8 KXS17611.1 - 0.24 10.8 4.4 0.53 9.7 4.4 1.6 1 0 0 1 1 1 0 Peptidase_C39 like family Tropomyosin PF00261.20 KXS17611.1 - 0.29 10.5 55.2 0.087 12.2 42.4 3.1 1 1 1 2 2 2 0 Tropomyosin DUF812 PF05667.11 KXS17611.1 - 1.3 7.9 31.4 0.093 11.6 25.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF812) Abhydrolase_1 PF00561.20 KXS17612.1 - 2.3e-28 99.6 0.1 3.3e-28 99.0 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXS17612.1 - 1.6e-17 64.9 0.0 2.2e-17 64.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXS17612.1 - 4.1e-08 32.8 0.0 9.1e-08 31.7 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 KXS17612.1 - 0.0074 15.0 0.0 0.017 13.8 0.0 1.5 2 0 0 2 2 2 1 Ndr family Abhydrolase_4 PF08386.10 KXS17612.1 - 0.012 15.8 0.0 0.023 14.8 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein DLH PF01738.18 KXS17612.1 - 0.032 13.8 0.0 1.6 8.2 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family SH3_2 PF07653.17 KXS17613.1 - 0.061 13.0 0.1 0.17 11.6 0.1 1.8 1 0 0 1 1 1 0 Variant SH3 domain PX PF00787.24 KXS17613.1 - 0.064 13.3 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 PX domain SH3_1 PF00018.28 KXS17613.1 - 0.45 10.2 1.7 3.8 7.2 0.1 2.5 2 0 0 2 2 2 0 SH3 domain MFS_1 PF07690.16 KXS17615.1 - 1.3e-07 30.9 23.0 0.002 17.1 2.0 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_tail_S PF05069.13 KXS17615.1 - 0.17 11.7 0.3 0.5 10.2 0.1 1.8 2 0 0 2 2 2 0 Phage virion morphogenesis family UNC-93 PF05978.16 KXS17615.1 - 8.7 6.0 14.8 0.076 12.7 5.3 2.4 3 0 0 3 3 3 0 Ion channel regulatory protein UNC-93 AhpC-TSA PF00578.21 KXS17616.1 - 1.6e-39 134.6 0.0 2e-39 134.3 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KXS17616.1 - 5.1e-16 58.7 0.0 6.3e-16 58.4 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 KXS17616.1 - 7.6e-10 38.5 0.1 1.4e-09 37.6 0.1 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin SCO1-SenC PF02630.14 KXS17616.1 - 0.0064 16.4 0.0 0.015 15.2 0.0 1.5 2 0 0 2 2 2 1 SCO1/SenC AhpC-TSA_2 PF13911.6 KXS17616.1 - 0.12 12.5 0.0 1.1 9.4 0.0 1.9 1 1 1 2 2 2 0 AhpC/TSA antioxidant enzyme WW PF00397.26 KXS17617.1 - 8.6e-11 41.7 1.8 1.9e-10 40.7 1.8 1.6 1 0 0 1 1 1 1 WW domain Mgm101p PF06420.12 KXS17618.1 - 6.6e-72 240.6 0.0 8.2e-72 240.3 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 Phage_Gp23 PF10669.9 KXS17620.1 - 7.5 6.9 9.2 1.7 9.0 0.9 2.1 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) Methyltransf_31 PF13847.6 KXS17621.1 - 3.8e-13 49.5 0.0 7.3e-13 48.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXS17621.1 - 2.4e-09 37.0 0.0 4.9e-05 22.9 0.1 2.2 2 0 0 2 2 2 2 Methyltransferase small domain Methyltransf_23 PF13489.6 KXS17621.1 - 4.4e-08 33.1 0.0 1.3e-07 31.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXS17621.1 - 5.8e-08 33.3 0.0 1.1e-06 29.2 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXS17621.1 - 1.3e-06 29.1 0.0 5e-06 27.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXS17621.1 - 4.9e-06 27.1 0.0 2e-05 25.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 KXS17621.1 - 0.00096 18.7 0.0 0.0017 17.9 0.0 1.4 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_32 PF13679.6 KXS17621.1 - 0.0013 18.8 0.0 0.0021 18.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KXS17621.1 - 0.0017 17.7 0.0 0.023 14.0 0.0 2.1 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.13 KXS17621.1 - 0.0052 16.2 0.2 0.015 14.7 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) TPMT PF05724.11 KXS17621.1 - 0.015 15.0 0.0 0.15 11.7 0.0 2.1 1 1 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) MetW PF07021.12 KXS17621.1 - 0.023 14.3 0.0 0.036 13.7 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW GidB PF02527.15 KXS17621.1 - 0.046 13.0 0.0 6.6 6.0 0.0 2.3 2 0 0 2 2 2 0 rRNA small subunit methyltransferase G Cons_hypoth95 PF03602.15 KXS17621.1 - 0.081 12.6 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 TehB PF03848.14 KXS17621.1 - 0.13 11.7 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB Sel1 PF08238.12 KXS17622.1 - 6.9e-52 172.7 26.6 4.8e-07 30.2 0.4 10.4 10 0 0 10 10 10 9 Sel1 repeat TPR_2 PF07719.17 KXS17622.1 - 0.0071 16.4 18.2 0.045 13.9 0.1 6.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 KXS17622.1 - 0.025 15.2 0.3 0.025 15.2 0.3 7.1 6 2 1 7 7 7 0 Tetratricopeptide repeat TPR_1 PF00515.28 KXS17622.1 - 0.038 13.8 8.4 0.23 11.3 0.1 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat MIT PF04212.18 KXS17622.1 - 0.22 11.6 1.2 18 5.5 0.1 3.5 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain KAR9 PF08580.10 KXS17622.1 - 0.57 8.7 6.4 0.99 7.9 6.4 1.3 1 0 0 1 1 1 0 Yeast cortical protein KAR9 TPR_7 PF13176.6 KXS17622.1 - 2.8 8.2 5.9 18 5.6 0.1 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat Sel1 PF08238.12 KXS17623.1 - 1.6e-61 203.3 31.3 5.5e-10 39.6 0.3 7.3 7 0 0 7 7 7 7 Sel1 repeat Pkinase_Tyr PF07714.17 KXS17623.1 - 0.00028 20.2 0.1 0.0017 17.7 0.0 2.0 1 1 1 2 2 2 1 Protein tyrosine kinase TPR_16 PF13432.6 KXS17623.1 - 0.16 12.6 23.7 0.61 10.8 1.0 5.7 5 1 1 6 6 6 0 Tetratricopeptide repeat TAP_C PF03943.13 KXS17623.1 - 1.7 8.3 5.9 14 5.5 0.2 3.8 4 0 0 4 4 4 0 TAP C-terminal domain TPR_2 PF07719.17 KXS17623.1 - 2.6 8.4 25.7 19 5.7 0.1 8.1 7 1 0 7 7 7 0 Tetratricopeptide repeat TPR_14 PF13428.6 KXS17623.1 - 9.1 7.4 18.2 10 7.3 0.5 5.8 6 1 1 7 7 7 0 Tetratricopeptide repeat PITH PF06201.13 KXS17624.1 - 9e-39 133.1 0.0 1.1e-38 132.9 0.0 1.1 1 0 0 1 1 1 1 PITH domain F-box-like PF12937.7 KXS17626.1 - 8.3e-07 28.8 1.6 1e-06 28.5 0.1 1.9 2 0 0 2 2 2 1 F-box-like zf-RING_2 PF13639.6 KXS17628.1 - 3.5e-12 46.5 4.8 6e-12 45.7 4.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KXS17628.1 - 1.6e-09 37.3 0.9 3.2e-09 36.4 0.9 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 KXS17628.1 - 3.6e-09 36.3 1.1 6.1e-09 35.6 1.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXS17628.1 - 5.5e-09 35.7 3.6 9.6e-09 34.9 3.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXS17628.1 - 1.3e-08 34.7 2.9 3.9e-07 30.0 4.6 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 KXS17628.1 - 3.9e-08 33.5 2.9 1e-07 32.1 2.9 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 KXS17628.1 - 3e-06 27.0 1.2 5.1e-06 26.2 1.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KXS17628.1 - 1e-05 25.5 1.4 1.9e-05 24.6 1.4 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 KXS17628.1 - 1.5e-05 24.8 0.7 2.8e-05 24.0 0.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.6 KXS17628.1 - 2.8e-05 23.8 1.7 5.5e-05 22.9 1.7 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 KXS17628.1 - 0.00014 21.6 5.9 0.0011 18.8 4.9 2.2 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KXS17628.1 - 0.00017 21.7 3.4 0.00033 20.8 3.4 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 KXS17628.1 - 0.044 13.6 1.2 0.077 12.8 1.2 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Rad50_zn_hook PF04423.14 KXS17628.1 - 0.072 12.9 0.2 0.49 10.3 0.0 2.1 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-C3H2C3 PF17122.5 KXS17628.1 - 0.077 13.0 2.3 0.19 11.8 2.3 1.7 1 0 0 1 1 1 0 Zinc-finger Zn_ribbon_17 PF17120.5 KXS17628.1 - 0.16 11.6 2.0 0.35 10.5 2.0 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 KXS17628.1 - 2.9 8.1 4.2 17 5.7 4.2 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain LIAS_N PF16881.5 KXS17629.1 - 1.2e-20 73.9 0.5 5.3e-19 68.6 0.5 2.3 1 1 0 1 1 1 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 KXS17629.1 - 1.2e-11 45.2 0.0 2.3e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily PRA1 PF03208.19 KXS17630.1 - 8.9e-24 83.7 1.9 2.2e-23 82.5 1.9 1.7 1 0 0 1 1 1 1 PRA1 family protein F-box-like PF12937.7 KXS17630.1 - 1.7e-06 27.8 2.9 4.2e-06 26.6 2.9 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXS17630.1 - 0.0013 18.5 2.3 0.0013 18.5 2.3 2.2 2 0 0 2 2 2 1 F-box domain RNA_pol_N PF01194.17 KXS17631.1 - 1.6e-32 111.6 0.6 1.8e-32 111.4 0.6 1.0 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit CAMSAP_CH PF11971.8 KXS17631.1 - 0.067 13.0 0.1 0.085 12.7 0.1 1.1 1 0 0 1 1 1 0 CAMSAP CH domain RINGv PF12906.7 KXS17632.1 - 6.4e-13 48.6 9.9 1.1e-12 47.9 9.9 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 KXS17632.1 - 0.073 13.4 7.9 0.19 12.1 8.1 1.6 1 1 0 1 1 1 0 Ring finger domain PHD PF00628.29 KXS17632.1 - 0.074 13.0 6.1 0.14 12.1 6.1 1.4 1 0 0 1 1 1 0 PHD-finger PRRSV_2b PF07069.11 KXS17632.1 - 0.33 11.5 2.0 0.4 11.2 0.3 1.9 2 0 0 2 2 2 0 Porcine reproductive and respiratory syndrome virus 2b FANCL_C PF11793.8 KXS17632.1 - 0.57 10.4 3.6 1.1 9.5 3.6 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain DUF4045 PF13254.6 KXS17632.1 - 5.6 6.5 6.4 8.9 5.8 6.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Bap31 PF05529.12 KXS17634.1 - 5.6e-27 94.2 3.5 6.9e-27 93.9 3.5 1.1 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region ATG16 PF08614.11 KXS17635.1 - 0.00026 21.3 1.4 0.0009 19.5 1.4 1.9 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) UPF0242 PF06785.11 KXS17635.1 - 0.015 15.4 0.1 0.024 14.8 0.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus KASH_CCD PF14662.6 KXS17635.1 - 0.033 14.0 1.2 0.057 13.2 1.2 1.3 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Fez1 PF06818.15 KXS17635.1 - 0.062 13.7 1.8 0.099 13.1 1.8 1.2 1 0 0 1 1 1 0 Fez1 DUF3972 PF13118.6 KXS17635.1 - 0.1 13.0 0.1 0.21 12.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3972) DivIVA PF05103.13 KXS17635.1 - 0.17 12.0 0.3 0.77 9.8 0.1 1.9 1 1 1 2 2 2 0 DivIVA protein bZIP_1 PF00170.21 KXS17635.1 - 0.24 11.5 2.0 1.5 9.0 0.4 2.4 2 0 0 2 2 2 0 bZIP transcription factor CENP-F_leu_zip PF10473.9 KXS17635.1 - 0.32 11.0 4.2 2.1 8.3 4.2 1.9 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IQCJ-SCHIP1 PF15157.6 KXS17635.1 - 0.52 10.1 8.8 0.57 10.0 1.5 2.8 1 1 2 3 3 3 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif ketoacyl-synt PF00109.26 KXS17636.1 - 9.6e-64 215.4 0.0 7.9e-63 212.4 0.0 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KXS17636.1 - 8.5e-35 119.3 0.1 2.7e-34 117.7 0.0 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KXS17636.1 - 1.7e-06 28.4 0.0 3.3e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 KXS17636.1 - 7e-05 22.3 0.1 0.00083 18.8 0.1 2.0 2 0 0 2 2 2 1 Thiolase, N-terminal domain DAGK_cat PF00781.24 KXS17636.1 - 0.024 14.2 0.0 0.053 13.1 0.0 1.5 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain PepSY_TM_like_2 PF16357.5 KXS17637.1 - 2.7 7.9 5.3 3.1 7.7 4.7 1.4 1 1 0 1 1 1 0 Putative PepSY_TM-like UPF0242 PF06785.11 KXS17637.1 - 8.6 6.4 25.1 69 3.5 23.7 2.3 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus LMBR1 PF04791.16 KXS17637.1 - 9.9 4.9 11.8 12 4.7 11.8 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein SH3_9 PF14604.6 KXS17638.1 - 2.5e-11 43.3 0.0 4.6e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXS17638.1 - 5.9e-08 32.2 0.0 1.1e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 SH3 domain Rax2 PF12768.7 KXS17638.1 - 0.0016 17.9 0.0 0.0024 17.4 0.0 1.3 1 0 0 1 1 1 1 Cortical protein marker for cell polarity SH3_2 PF07653.17 KXS17638.1 - 0.0026 17.4 0.0 0.0052 16.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SKG6 PF08693.10 KXS17638.1 - 0.0082 15.5 5.9 0.0082 15.5 5.9 2.0 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Oxidored_q2 PF00420.24 KXS17638.1 - 0.058 13.0 0.3 0.11 12.1 0.3 1.3 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L RF-1 PF00472.20 KXS17639.1 - 1.4e-20 73.3 1.2 3.1e-20 72.3 1.2 1.5 1 0 0 1 1 1 1 RF-1 domain Octopine_DH PF02317.17 KXS17639.1 - 0.013 15.6 0.1 0.017 15.2 0.1 1.3 1 0 0 1 1 1 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain MIP-T3 PF10243.9 KXS17640.1 - 1.8e-36 124.5 0.0 2.9e-36 123.9 0.0 1.3 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 CH-like domain MIP-T3_C PF17749.1 KXS17640.1 - 2.6e-18 66.4 0.0 2.6e-18 66.4 0.0 1.9 2 0 0 2 2 2 1 Microtubule-binding protein MIP-T3 C-terminal region Apt1 PF10351.9 KXS17640.1 - 3.4 6.4 8.4 4.6 6.0 8.4 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Jnk-SapK_ap_N PF09744.9 KXS17640.1 - 3.8 7.7 6.7 0.4 10.9 1.1 2.0 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 RF-1 PF00472.20 KXS17641.1 - 6.2e-14 51.9 0.0 7.2e-14 51.7 0.0 1.1 1 0 0 1 1 1 1 RF-1 domain Phage_int_SAM_6 PF18644.1 KXS17641.1 - 0.059 13.4 0.0 0.079 13.0 0.0 1.2 1 0 0 1 1 1 0 Phage integrase SAM-like domain GST_N PF02798.20 KXS17642.1 - 1.6e-13 50.8 0.0 4.9e-13 49.2 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KXS17642.1 - 6.4e-13 48.9 0.0 1.1e-12 48.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KXS17642.1 - 2.7e-10 40.4 0.0 1.7e-09 37.8 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KXS17642.1 - 3.7e-05 23.8 0.0 0.00015 21.9 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain CoA_transf_3 PF02515.17 KXS17643.1 - 3.5e-112 375.2 0.0 4e-112 375.0 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III Creatinase_N PF01321.18 KXS17643.1 - 0.048 14.3 0.0 0.1 13.3 0.0 1.4 1 0 0 1 1 1 0 Creatinase/Prolidase N-terminal domain SAM_4 PF18017.1 KXS17643.1 - 0.092 12.7 0.0 0.81 9.7 0.0 2.2 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) MFS_1 PF07690.16 KXS17644.1 - 2.3e-22 79.4 36.0 2.3e-22 79.4 36.0 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily PsbJ PF01788.17 KXS17645.1 - 0.48 10.3 3.7 1.3 8.9 3.7 1.8 1 0 0 1 1 1 0 PsbJ DUF563 PF04577.14 KXS17646.1 - 2.7e-17 63.6 0.0 5.2e-17 62.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF563) RAI16-like PF10257.9 KXS17648.1 - 1.6e-26 93.1 0.0 5e-26 91.4 0.0 1.8 1 1 0 1 1 1 1 Retinoic acid induced 16-like protein Pap_E4 PF02711.14 KXS17648.1 - 0.7 10.9 7.7 0.12 13.3 1.2 3.0 3 0 0 3 3 3 0 E4 protein PDEase_I PF00233.19 KXS17649.1 - 4.8e-60 203.2 4.5 6.8e-60 202.7 4.5 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 KXS17649.1 - 1.2e-17 64.8 0.0 2.9e-17 63.6 0.0 1.7 1 1 0 1 1 1 1 GAF domain GAF_2 PF13185.6 KXS17649.1 - 2.1e-10 41.0 0.0 1.7e-09 38.1 0.0 2.4 2 0 0 2 2 2 1 GAF domain GAF_3 PF13492.6 KXS17649.1 - 7.7e-06 26.3 0.0 4.2e-05 23.9 0.0 2.2 2 0 0 2 2 2 1 GAF domain RhoGEF PF00621.20 KXS17650.1 - 2.7e-18 66.9 0.1 3.2e-18 66.6 0.1 1.1 1 0 0 1 1 1 1 RhoGEF domain Hamartin PF04388.12 KXS17651.1 - 0.00049 18.9 9.5 0.00054 18.8 9.5 1.0 1 0 0 1 1 1 1 Hamartin protein Med13_C PF06333.12 KXS17651.1 - 0.18 11.0 4.3 0.19 11.0 4.3 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain DUF4698 PF15769.5 KXS17651.1 - 0.19 10.8 8.5 0.21 10.6 8.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4698) SGT1 PF07093.11 KXS17651.1 - 0.2 10.1 8.3 0.24 9.8 8.3 1.1 1 0 0 1 1 1 0 SGT1 protein SOBP PF15279.6 KXS17651.1 - 7 7.2 6.2 7.8 7.0 6.2 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein SpoIIIAH PF12685.7 KXS17651.1 - 7.4 6.3 20.9 9.9 5.9 20.9 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein Epimerase PF01370.21 KXS17652.1 - 5.5e-18 65.3 0.0 7.2e-18 64.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXS17652.1 - 2e-15 56.6 0.0 2.6e-15 56.2 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KXS17652.1 - 1.2e-07 31.8 0.0 2.2e-07 31.0 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KXS17652.1 - 2.1e-07 30.4 0.0 2.9e-05 23.4 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein GDP_Man_Dehyd PF16363.5 KXS17652.1 - 0.00012 21.6 0.0 0.00025 20.5 0.0 1.6 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 KXS17652.1 - 0.00021 20.9 0.0 0.00036 20.2 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.15 KXS17652.1 - 0.00039 19.6 0.0 0.00055 19.2 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.25 KXS17652.1 - 0.00061 19.3 0.0 0.0018 17.7 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KXS17652.1 - 0.0066 16.4 0.1 0.017 15.1 0.1 1.6 1 1 0 1 1 1 1 KR domain Nic96 PF04097.14 KXS17653.1 - 5.6e-109 365.3 0.0 2.8e-59 201.2 0.0 2.4 2 1 0 2 2 2 2 Nup93/Nic96 SHE3 PF17078.5 KXS17653.1 - 0.44 10.2 1.2 1.8 8.2 0.0 2.3 3 0 0 3 3 3 0 SWI5-dependent HO expression protein 3 PTCB-BRCT PF12738.7 KXS17654.1 - 1.7e-31 107.9 0.0 2.2e-15 56.3 0.1 5.0 6 0 0 6 6 6 2 twin BRCT domain BRCT PF00533.26 KXS17654.1 - 2.1e-24 85.7 0.0 1.9e-10 41.0 0.0 3.8 3 0 0 3 3 3 3 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KXS17654.1 - 2.4e-17 63.1 0.0 0.056 13.9 0.0 6.2 6 0 0 6 6 6 4 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 KXS17654.1 - 4.5e-08 33.3 0.0 0.00022 21.4 0.0 3.8 4 0 0 4 4 4 2 DNA ligase 3 BRCT domain RTT107_BRCT_5 PF16770.5 KXS17654.1 - 6.7e-08 32.3 0.0 0.00014 21.7 0.0 4.2 4 1 1 5 5 5 1 Regulator of Ty1 transposition protein 107 BRCT domain Dynamin_M PF01031.20 KXS17655.1 - 5.8e-40 137.3 0.1 8.9e-40 136.7 0.1 1.3 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 KXS17655.1 - 1.1e-24 87.4 0.2 2.1e-24 86.5 0.2 1.5 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 KXS17655.1 - 5.7e-06 26.4 0.0 1.9e-05 24.7 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_21 PF13304.6 KXS17655.1 - 0.013 15.4 0.0 0.026 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Roc PF08477.13 KXS17655.1 - 0.047 13.9 0.0 0.13 12.5 0.0 1.8 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 KXS17655.1 - 0.063 13.8 0.0 0.18 12.3 0.0 1.8 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 KXS17655.1 - 0.081 12.7 0.0 0.21 11.3 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain GED PF02212.18 KXS17655.1 - 0.33 11.1 2.8 41 4.4 0.0 3.5 4 0 0 4 4 4 0 Dynamin GTPase effector domain Glyco_hydro_114 PF03537.13 KXS17656.1 - 7.3e-74 248.0 0.0 1.1e-73 247.4 0.0 1.2 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 EF-hand_6 PF13405.6 KXS17657.1 - 0.0025 17.6 0.1 0.006 16.4 0.1 1.6 1 0 0 1 1 1 1 EF-hand domain EF-hand_8 PF13833.6 KXS17657.1 - 0.0045 16.8 0.0 0.01 15.7 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 KXS17657.1 - 0.0048 16.3 0.0 0.0094 15.4 0.0 1.5 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.6 KXS17657.1 - 0.014 14.9 0.0 0.028 13.9 0.0 1.5 1 0 0 1 1 1 0 EF hand EF-hand_7 PF13499.6 KXS17657.1 - 0.037 14.5 0.0 0.061 13.8 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain pair Hydrolase_4 PF12146.8 KXS17659.1 - 0.00027 20.3 0.1 0.0004 19.7 0.1 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KXS17659.1 - 0.038 13.6 0.2 0.071 12.7 0.2 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Sel1 PF08238.12 KXS17660.1 - 7.8e-36 121.7 14.5 5.2e-07 30.1 0.2 8.4 8 0 0 8 8 8 7 Sel1 repeat TPR_2 PF07719.17 KXS17660.1 - 0.00017 21.5 17.1 0.2 11.8 0.0 7.8 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_7 PF13176.6 KXS17660.1 - 0.00035 20.4 0.4 1.1 9.5 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 KXS17660.1 - 0.0086 15.9 7.3 1.3 8.9 0.0 5.6 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_16 PF13432.6 KXS17660.1 - 0.017 15.8 13.7 5.1 7.8 0.1 5.1 4 2 0 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KXS17660.1 - 0.056 13.7 0.5 5.2 7.4 0.0 3.7 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 KXS17660.1 - 0.083 13.3 0.1 7 7.3 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat PatG_D PF18047.1 KXS17660.1 - 0.12 12.8 0.0 25 5.4 0.0 2.4 2 0 0 2 2 2 0 PatG Domain TPR_12 PF13424.6 KXS17660.1 - 0.16 12.2 6.5 0.92 9.8 0.1 4.3 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 KXS17660.1 - 0.59 10.1 0.0 0.59 10.1 0.0 3.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 KXS17660.1 - 1.7 9.4 10.0 27 5.7 0.1 5.7 7 0 0 7 7 7 0 Tetratricopeptide repeat Sas10_Utp3 PF04000.15 KXS17663.1 - 5.8e-10 39.7 0.0 1.5e-09 38.4 0.0 1.7 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Aa_trans PF01490.18 KXS17664.1 - 1.3e-50 172.4 0.6 1.8e-50 171.9 0.6 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein SH3_9 PF14604.6 KXS17665.1 - 0.00099 18.9 0.2 0.0022 17.8 0.2 1.6 1 0 0 1 1 1 1 Variant SH3 domain Phage_HK97_TLTM PF06120.11 KXS17665.1 - 0.015 14.5 0.2 0.022 14.0 0.2 1.1 1 0 0 1 1 1 0 Tail length tape measure protein Mito_carr PF00153.27 KXS17666.1 - 2.7e-71 235.6 2.4 2.7e-24 84.9 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein WD40 PF00400.32 KXS17667.1 - 1e-13 51.5 8.4 0.00017 22.3 0.6 5.0 5 0 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.8 KXS17667.1 - 2e-05 23.5 0.0 0.00085 18.1 0.0 2.3 2 0 0 2 2 2 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 KXS17667.1 - 0.019 15.2 0.3 0.8 10.0 0.1 2.9 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain BAT2_N PF07001.11 KXS17667.1 - 0.14 12.6 1.6 4 7.9 0.1 3.1 3 1 0 3 3 3 0 BAT2 N-terminus PQQ_3 PF13570.6 KXS17667.1 - 1.6 9.3 8.0 2.3 8.8 0.6 3.5 3 1 1 4 4 4 0 PQQ-like domain Pre-PUA PF17832.1 KXS17668.1 - 2.3e-27 95.5 0.1 3.1e-27 95.1 0.1 1.2 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 KXS17668.1 - 5.4e-12 45.5 0.0 9.7e-12 44.7 0.0 1.5 1 0 0 1 1 1 1 PUA domain SH3_9 PF14604.6 KXS17669.1 - 9.1e-08 31.8 0.0 5.9e-07 29.2 0.0 2.3 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 KXS17669.1 - 0.00045 19.8 0.0 0.00099 18.7 0.0 1.5 1 0 0 1 1 1 1 SH3 domain Linker_histone PF00538.19 KXS17671.1 - 4e-06 27.1 0.0 1e-05 25.8 0.0 1.7 1 0 0 1 1 1 1 linker histone H1 and H5 family Methyltransf_7 PF03492.15 KXS17672.1 - 0.27 10.4 0.0 7.1 5.7 0.0 2.1 2 0 0 2 2 2 0 SAM dependent carboxyl methyltransferase ABC_tran PF00005.27 KXS17673.1 - 9.9e-25 87.6 0.0 1.5e-24 87.1 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 KXS17673.1 - 4.5e-20 72.0 21.5 4.5e-20 72.0 21.5 1.8 2 0 0 2 2 2 1 ABC-2 type transporter AAA_21 PF13304.6 KXS17673.1 - 0.00064 19.6 0.0 0.3 10.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KXS17673.1 - 0.0012 18.7 0.3 0.0022 17.9 0.3 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 KXS17673.1 - 0.0019 18.6 0.0 0.0036 17.7 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.6 KXS17673.1 - 0.0072 16.6 0.0 0.014 15.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 KXS17673.1 - 0.0096 15.0 0.1 0.017 14.2 0.1 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_29 PF13555.6 KXS17673.1 - 0.041 13.6 1.2 0.097 12.4 1.2 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.6 KXS17673.1 - 0.051 13.3 0.6 0.088 12.5 0.6 1.3 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.17 KXS17673.1 - 0.057 13.5 1.1 0.099 12.7 1.1 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_25 PF13481.6 KXS17673.1 - 0.091 12.3 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KXS17673.1 - 0.097 12.6 0.1 0.18 11.7 0.1 1.4 1 0 0 1 1 1 0 NACHT domain AAA_22 PF13401.6 KXS17673.1 - 0.12 12.7 0.1 0.29 11.4 0.1 1.6 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 KXS17673.1 - 0.15 12.1 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase Pox_A32 PF04665.12 KXS17673.1 - 0.25 10.8 0.3 0.44 10.0 0.3 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein NAD_binding_8 PF13450.6 KXS17674.1 - 2.6e-11 43.6 0.0 4.8e-11 42.7 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KXS17674.1 - 1.7e-08 34.2 0.1 3.2e-06 26.7 0.0 2.1 1 1 1 2 2 2 2 Flavin containing amine oxidoreductase DAO PF01266.24 KXS17674.1 - 5.6e-07 29.5 0.0 7.4e-05 22.5 0.0 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KXS17674.1 - 0.0026 17.7 0.1 0.023 14.7 0.0 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.17 KXS17674.1 - 0.0049 16.1 0.0 0.009 15.3 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 KXS17674.1 - 0.022 13.9 0.0 0.034 13.3 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.14 KXS17674.1 - 0.079 12.2 0.2 0.13 11.5 0.0 1.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 KXS17674.1 - 0.085 12.4 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox_3 PF13738.6 KXS17674.1 - 0.2 10.9 0.1 0.57 9.4 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KXS17674.1 - 0.22 10.7 0.0 0.39 9.9 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain COPIIcoated_ERV PF07970.12 KXS17676.1 - 8.2e-76 254.7 0.3 1.1e-75 254.3 0.3 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 KXS17676.1 - 2.5e-29 101.5 0.5 7e-29 100.0 0.0 1.9 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Pkinase PF00069.25 KXS17677.1 - 1.2e-67 228.0 0.0 1.4e-67 227.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS17677.1 - 3.1e-46 157.8 0.0 4e-46 157.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXS17677.1 - 2.3e-06 26.7 0.0 3.3e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 KXS17677.1 - 0.0013 17.8 0.0 0.045 12.7 0.0 2.1 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KXS17677.1 - 0.014 14.7 0.0 0.022 14.1 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Mito_carr PF00153.27 KXS17678.1 - 6.5e-57 189.5 0.0 4.7e-21 74.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein 2-ph_phosp PF04029.14 KXS17679.1 - 0.11 11.7 0.3 0.24 10.6 0.0 1.6 2 0 0 2 2 2 0 2-phosphosulpholactate phosphatase PNISR PF15996.5 KXS17679.1 - 3.2 8.0 9.4 1 9.6 5.9 2.0 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR ATP_bind_1 PF03029.17 KXS17680.1 - 9.1e-75 251.5 0.0 1.3e-74 251.0 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 KXS17680.1 - 0.00015 22.2 0.7 0.0009 19.7 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain MeaB PF03308.16 KXS17680.1 - 0.00043 19.3 0.3 0.08 11.9 0.0 2.3 2 1 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 KXS17680.1 - 0.00053 20.0 0.0 0.0038 17.3 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_24 PF13479.6 KXS17680.1 - 0.00054 19.7 0.0 0.00096 18.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KXS17680.1 - 0.0007 19.8 0.0 0.0015 18.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain GTP_EFTU PF00009.27 KXS17680.1 - 0.0011 18.6 0.0 0.012 15.2 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KXS17680.1 - 0.0051 16.2 0.0 2.2 7.5 0.0 2.1 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region cobW PF02492.19 KXS17680.1 - 0.008 15.8 0.0 0.58 9.7 0.0 2.3 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 KXS17680.1 - 0.0089 16.6 0.0 0.031 14.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KXS17680.1 - 0.0097 16.2 0.5 0.032 14.5 0.0 2.2 2 1 1 3 3 1 1 AAA domain NACHT PF05729.12 KXS17680.1 - 0.0097 15.8 2.1 0.015 15.2 0.0 2.1 2 0 0 2 2 2 1 NACHT domain AAA_30 PF13604.6 KXS17680.1 - 0.01 15.5 0.6 0.17 11.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KXS17680.1 - 0.017 14.4 0.0 0.046 13.0 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin FeoB_N PF02421.18 KXS17680.1 - 0.018 14.5 0.0 0.2 11.2 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B SRP54 PF00448.22 KXS17680.1 - 0.021 14.5 0.0 0.061 12.9 0.0 1.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Viral_helicase1 PF01443.18 KXS17680.1 - 0.028 14.2 0.0 0.058 13.1 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RsgA_GTPase PF03193.16 KXS17680.1 - 0.041 13.8 0.0 7 6.5 0.0 2.9 3 0 0 3 3 2 0 RsgA GTPase Glyco_tranf_2_3 PF13641.6 KXS17680.1 - 0.05 13.5 0.0 0.083 12.8 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase like family 2 LpxK PF02606.14 KXS17680.1 - 0.053 12.6 0.0 0.081 12.0 0.0 1.2 1 0 0 1 1 1 0 Tetraacyldisaccharide-1-P 4'-kinase AAA_19 PF13245.6 KXS17680.1 - 0.061 13.7 0.0 0.061 13.7 0.0 1.6 2 0 0 2 2 1 0 AAA domain Roc PF08477.13 KXS17680.1 - 0.068 13.4 0.0 0.59 10.4 0.0 2.2 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase MobB PF03205.14 KXS17680.1 - 0.075 12.9 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B IIGP PF05049.13 KXS17680.1 - 0.096 11.7 0.1 0.7 8.9 0.0 2.1 1 1 1 2 2 2 0 Interferon-inducible GTPase (IIGP) NB-ARC PF00931.22 KXS17680.1 - 0.14 11.3 0.0 0.29 10.3 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Thymidylate_kin PF02223.17 KXS17680.1 - 0.14 11.8 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Thymidylate kinase KAP_NTPase PF07693.14 KXS17680.1 - 0.19 11.0 0.0 0.27 10.4 0.0 1.6 1 1 0 1 1 1 0 KAP family P-loop domain PduV-EutP PF10662.9 KXS17680.1 - 0.2 11.4 0.0 0.88 9.3 0.0 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 KXS17680.1 - 0.26 10.8 0.5 0.43 10.1 0.0 1.6 2 0 0 2 2 1 0 P-loop containing dynein motor region RCDG1 PF15725.5 KXS17680.1 - 0.98 9.9 7.6 0.54 10.7 4.3 2.4 3 0 0 3 3 2 0 Renal cancer differentiation gene 1 protein Elongin_A PF06881.11 KXS17681.1 - 6.1e-16 58.9 0.0 1.1e-15 58.0 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A PRP1_N PF06424.12 KXS17682.1 - 3.4e-48 163.8 0.8 6.8e-48 162.8 0.8 1.5 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.6 KXS17682.1 - 8.6e-25 85.3 37.4 0.00024 21.6 0.0 14.1 8 4 7 15 15 15 7 Tetratricopeptide repeat TPR_19 PF14559.6 KXS17682.1 - 4.4e-19 68.7 10.9 7.4e-05 23.2 0.7 8.8 8 2 2 10 10 9 3 Tetratricopeptide repeat TPR_16 PF13432.6 KXS17682.1 - 7.4e-11 42.5 19.6 0.0012 19.4 3.3 7.7 7 1 1 8 8 8 2 Tetratricopeptide repeat TPR_2 PF07719.17 KXS17682.1 - 8.3e-09 34.9 6.8 0.23 11.7 0.0 9.4 11 0 0 11 11 10 2 Tetratricopeptide repeat TPR_17 PF13431.6 KXS17682.1 - 4e-07 30.0 0.1 8.3 7.0 0.1 9.2 11 1 1 12 12 11 1 Tetratricopeptide repeat TPR_8 PF13181.6 KXS17682.1 - 0.00026 21.0 3.4 7.8 7.0 0.0 7.2 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_1 PF00515.28 KXS17682.1 - 0.00046 19.9 1.0 1.6 8.6 0.0 4.2 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 KXS17682.1 - 0.0018 18.2 0.3 15 5.9 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 KXS17682.1 - 0.0027 17.4 1.2 1 9.1 0.0 5.1 6 0 0 6 6 6 1 TPR repeat TPR_6 PF13174.6 KXS17682.1 - 0.0028 18.2 12.7 4.9 8.0 0.0 9.1 11 0 0 11 11 11 1 Tetratricopeptide repeat NARP1 PF12569.8 KXS17682.1 - 0.0034 16.4 3.6 0.21 10.5 0.0 4.0 4 1 1 5 5 5 1 NMDA receptor-regulated protein 1 TPR_12 PF13424.6 KXS17682.1 - 0.0057 16.9 11.4 0.97 9.8 0.0 6.8 8 1 1 9 9 7 1 Tetratricopeptide repeat FAT PF02259.23 KXS17682.1 - 0.016 14.4 5.6 0.25 10.5 5.5 2.8 1 1 0 1 1 1 0 FAT domain Suf PF05843.14 KXS17682.1 - 0.057 13.4 1.3 3.5 7.5 0.0 3.6 5 0 0 5 5 5 0 Suppressor of forked protein (Suf) PdxA PF04166.12 KXS17682.1 - 0.076 12.4 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Pyridoxal phosphate biosynthetic protein PdxA ANAPC3 PF12895.7 KXS17682.1 - 0.13 12.6 0.0 23 5.3 0.0 3.7 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 KXS17682.1 - 1 9.6 9.2 1.7 8.9 0.0 4.9 5 1 0 5 5 5 0 Tetratricopeptide repeat FTO_CTD PF12934.7 KXS17683.1 - 0.036 13.8 0.2 0.036 13.8 0.2 2.6 2 1 1 3 3 3 0 FTO C-terminal domain Prominin PF05478.11 KXS17683.1 - 0.12 10.3 22.9 0.21 9.5 1.3 3.2 1 1 1 3 3 3 0 Prominin DUF1664 PF07889.12 KXS17683.1 - 0.14 12.2 21.5 2 8.4 1.1 4.3 3 2 1 4 4 4 0 Protein of unknown function (DUF1664) TACC_C PF05010.14 KXS17683.1 - 0.44 10.3 20.6 0.075 12.8 8.9 3.5 2 2 2 4 4 4 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal FapA PF03961.13 KXS17683.1 - 0.52 8.9 13.6 0.027 13.1 3.4 2.5 2 1 1 3 3 3 0 Flagellar Assembly Protein A NPV_P10 PF05531.12 KXS17683.1 - 0.78 10.2 18.7 4.3 7.9 0.1 5.3 4 2 1 5 5 5 0 Nucleopolyhedrovirus P10 protein FlaC_arch PF05377.11 KXS17683.1 - 1 9.8 17.5 1.1 9.7 1.8 5.4 4 1 0 5 5 4 0 Flagella accessory protein C (FlaC) LOH1CR12 PF10158.9 KXS17683.1 - 1.1 9.3 5.0 0.55 10.3 0.1 2.8 2 1 1 3 3 3 0 Tumour suppressor protein Allexi_40kDa PF05549.11 KXS17683.1 - 1.2 8.6 22.7 0.16 11.4 4.9 3.5 1 1 1 3 3 3 0 Allexivirus 40kDa protein ING PF12998.7 KXS17683.1 - 1.4 9.5 14.7 3.6 8.2 0.1 4.6 3 2 2 5 5 5 0 Inhibitor of growth proteins N-terminal histone-binding Sec34 PF04136.15 KXS17683.1 - 1.7 8.5 15.6 0.14 12.0 1.4 4.2 1 1 1 3 3 3 0 Sec34-like family Occludin_ELL PF07303.13 KXS17683.1 - 1.7 9.4 14.4 1.2 9.9 0.2 4.4 3 1 1 4 4 4 0 Occludin homology domain H-kinase_dim PF02895.14 KXS17683.1 - 1.9 8.9 13.7 0.74 10.2 1.0 4.1 3 1 0 3 3 3 0 Signal transducing histidine kinase, homodimeric domain FUSC PF04632.12 KXS17683.1 - 6.3 5.2 7.7 4.4 5.7 0.5 2.4 1 1 2 3 3 3 0 Fusaric acid resistance protein family ABC_tran_CTD PF16326.5 KXS17683.1 - 7.1 7.0 12.3 1.4 9.2 1.1 3.8 3 1 1 4 4 4 0 ABC transporter C-terminal domain Phage_HK97_TLTM PF06120.11 KXS17683.1 - 8.7 5.4 14.0 0.11 11.7 5.8 2.0 3 0 0 3 3 3 0 Tail length tape measure protein MutS_V PF00488.21 KXS17684.1 - 4.1e-73 245.4 0.2 7.3e-73 244.6 0.2 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KXS17684.1 - 2.2e-32 112.8 0.1 4e-32 112.0 0.1 1.4 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 KXS17684.1 - 2.6e-26 92.1 0.1 1.5e-25 89.7 0.0 2.4 3 0 0 3 3 3 1 MutS domain I MutS_II PF05188.17 KXS17684.1 - 9.3e-12 45.4 0.1 4.2e-11 43.3 0.0 2.1 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.18 KXS17684.1 - 8.4e-08 32.5 0.3 2.1e-07 31.2 0.3 1.6 1 0 0 1 1 1 1 MutS family domain IV Het-C PF07217.11 KXS17684.1 - 0.032 12.8 0.0 0.051 12.1 0.0 1.2 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C FAD_binding_3 PF01494.19 KXS17686.1 - 1.1e-14 54.5 0.0 2.8e-14 53.2 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain ANAPC4_WD40 PF12894.7 KXS17686.1 - 2.7e-09 37.2 0.7 0.0021 18.3 0.0 4.7 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 KXS17686.1 - 8.1e-07 28.4 0.3 0.00039 19.6 0.0 2.3 2 0 0 2 2 2 2 Coatomer WD associated region Clathrin PF00637.20 KXS17686.1 - 6e-06 26.2 0.1 0.0012 18.8 0.1 2.6 1 1 1 2 2 2 2 Region in Clathrin and VPS NAD_binding_8 PF13450.6 KXS17686.1 - 4.1e-05 23.7 0.5 0.00019 21.6 0.5 2.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXS17686.1 - 0.00059 19.2 0.9 0.021 14.0 0.6 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase F-box-like PF12937.7 KXS17686.1 - 0.0049 16.7 0.7 0.0049 16.7 0.7 2.3 3 0 0 3 3 1 1 F-box-like TPR_11 PF13414.6 KXS17686.1 - 0.021 14.5 0.1 0.096 12.4 0.0 2.2 2 0 0 2 2 2 0 TPR repeat FAD_binding_2 PF00890.24 KXS17686.1 - 0.032 13.3 4.3 0.06 12.4 4.3 1.4 1 0 0 1 1 1 0 FAD binding domain PD40 PF07676.12 KXS17686.1 - 0.097 12.6 0.2 4.1 7.5 0.0 3.1 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat DAO PF01266.24 KXS17686.1 - 0.099 12.2 7.6 0.092 12.3 5.6 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KXS17686.1 - 0.17 11.2 2.9 0.3 10.4 2.9 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KXS17686.1 - 0.18 11.0 3.9 0.3 10.3 3.9 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TPR_7 PF13176.6 KXS17686.1 - 0.2 11.8 0.2 10 6.4 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat F-box PF00646.33 KXS17686.1 - 0.26 11.2 4.1 3.4 7.6 0.3 2.7 2 0 0 2 2 2 0 F-box domain WD40 PF00400.32 KXS17686.1 - 0.28 12.1 10.3 3.9 8.5 0.1 5.8 7 0 0 7 7 5 0 WD domain, G-beta repeat zinc_ribbon_2 PF13240.6 KXS17686.1 - 0.35 10.7 3.4 0.28 11.0 1.3 2.0 2 0 0 2 2 2 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 KXS17686.1 - 0.65 9.5 6.4 1.7 8.2 6.4 1.7 1 0 0 1 1 1 0 zinc-ribbon domain DZR PF12773.7 KXS17686.1 - 1.2 9.2 5.8 4 7.5 5.8 1.8 1 1 0 1 1 1 0 Double zinc ribbon RRP36 PF06102.12 KXS17687.1 - 2.2e-42 144.8 14.5 6.7e-42 143.3 14.5 1.8 1 0 0 1 1 1 1 rRNA biogenesis protein RRP36 MFS_1 PF07690.16 KXS17688.1 - 1.2e-24 86.9 44.3 1.4e-12 47.2 14.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Gpr1_Fun34_YaaH PF01184.19 KXS17690.1 - 1.1e-09 38.3 21.4 1.4e-09 37.9 21.4 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Pox_VLTF3 PF04947.14 KXS17691.1 - 7.1e-12 45.4 0.2 1.2e-11 44.6 0.2 1.4 1 0 0 1 1 1 1 Poxvirus Late Transcription Factor VLTF3 like NOG1_N PF17835.1 KXS17691.1 - 0.041 13.9 0.0 1.1 9.2 0.0 2.4 2 0 0 2 2 2 0 NOG1 N-terminal helical domain Cytochrom_NNT PF03264.14 KXS17691.1 - 0.077 12.7 0.6 0.14 11.9 0.6 1.4 1 0 0 1 1 1 0 NapC/NirT cytochrome c family, N-terminal region Fib_alpha PF08702.10 KXS17692.1 - 0.16 12.1 2.3 1.8 8.7 0.3 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family zf-C3HC4_3 PF13920.6 KXS17695.1 - 4.4e-10 39.3 6.3 6.2e-10 38.8 6.3 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KXS17695.1 - 4e-06 26.6 5.1 6.6e-06 25.9 5.1 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KXS17695.1 - 0.00043 20.6 8.0 0.00065 20.0 8.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KXS17695.1 - 0.0098 15.7 5.3 0.015 15.1 5.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXS17695.1 - 0.23 11.4 6.5 0.39 10.7 6.5 1.3 1 0 0 1 1 1 0 zinc-RING finger domain F-box PF00646.33 KXS17696.1 - 0.0038 17.1 0.7 0.011 15.6 0.7 1.8 1 0 0 1 1 1 1 F-box domain AMP-binding PF00501.28 KXS17698.1 - 2.2e-70 237.4 0.0 1.8e-69 234.4 0.0 2.0 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXS17698.1 - 1.4e-16 61.2 0.4 4.7e-16 59.5 0.4 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Lactamase_B PF00753.27 KXS17698.1 - 0.047 13.7 2.7 0.55 10.2 0.3 2.8 3 0 0 3 3 3 0 Metallo-beta-lactamase superfamily NAD_binding_10 PF13460.6 KXS17699.1 - 9.6e-05 22.3 0.0 0.019 14.9 0.0 2.1 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KXS17699.1 - 0.0016 17.9 0.1 0.0093 15.4 0.0 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family CAP_N PF01213.19 KXS17700.1 - 1.9e-112 375.8 2.6 1.9e-112 375.8 2.6 1.6 1 1 1 2 2 2 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 KXS17700.1 - 5e-57 191.9 2.6 7.7e-57 191.3 2.6 1.3 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.12 KXS17700.1 - 1.8e-05 24.5 1.4 6.5e-05 22.7 1.4 1.8 1 1 0 1 1 1 1 Tubulin binding cofactor C RNA_lig_T4_1 PF09511.10 KXS17700.1 - 0.008 16.1 0.0 0.015 15.1 0.0 1.6 1 0 0 1 1 1 1 RNA ligase ADH_zinc_N PF00107.26 KXS17701.1 - 2.6e-19 69.5 0.0 4.4e-19 68.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KXS17701.1 - 1.3e-12 47.5 0.0 2.8e-12 46.5 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 KXS17701.1 - 4.2e-10 40.8 0.0 4.8e-09 37.4 0.0 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase DUF2052 PF09747.9 KXS17703.1 - 3.4e-34 118.7 5.4 1.6e-17 64.3 2.9 2.5 2 1 0 2 2 2 2 Coiled-coil domain containing protein (DUF2052) zf-RING_2 PF13639.6 KXS17705.1 - 7.1e-13 48.7 2.1 9.4e-13 48.3 2.1 1.2 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KXS17705.1 - 2.5e-09 36.8 2.2 3.5e-09 36.3 2.2 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KXS17705.1 - 3.4e-09 36.3 0.9 3.4e-09 36.3 0.9 1.7 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 KXS17705.1 - 1.1e-08 34.8 0.8 1.4e-08 34.4 0.8 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KXS17705.1 - 2e-08 34.4 3.0 5.5e-08 33.0 3.0 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KXS17705.1 - 1.2e-07 31.5 0.7 1.6e-07 31.1 0.7 1.2 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KXS17705.1 - 1.1e-06 28.4 0.8 1.4e-06 28.0 0.8 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXS17705.1 - 2e-05 24.5 0.5 3.6e-05 23.7 0.1 1.6 1 1 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 KXS17705.1 - 0.00089 19.3 3.0 0.0031 17.5 3.0 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 KXS17705.1 - 0.0013 18.5 1.5 0.002 17.9 1.5 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 KXS17705.1 - 0.0019 18.0 0.9 0.0037 17.1 0.9 1.4 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 KXS17705.1 - 0.069 12.8 3.7 0.13 12.0 3.7 1.5 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type Vps39_2 PF10367.9 KXS17705.1 - 0.12 12.8 0.6 0.23 11.9 0.1 1.7 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 zf-C3H2C3 PF17122.5 KXS17705.1 - 0.19 11.8 2.5 0.5 10.4 2.5 1.7 1 1 0 1 1 1 0 Zinc-finger FANCL_C PF11793.8 KXS17705.1 - 0.54 10.5 4.2 4.2 7.6 4.2 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain PHD PF00628.29 KXS17705.1 - 0.72 9.8 3.4 1.5 8.8 3.4 1.6 1 1 0 1 1 1 0 PHD-finger Big_9 PF17963.1 KXS17706.1 - 2.2e-08 34.7 31.3 1.5e-05 25.7 7.2 4.1 3 2 0 3 3 3 2 Bacterial Ig domain Cadherin_3 PF16184.5 KXS17706.1 - 3.3e-06 27.1 0.3 0.0062 16.5 0.0 2.4 2 0 0 2 2 2 2 Cadherin-like PA14 PF07691.12 KXS17706.1 - 3.2e-05 23.8 0.3 0.00016 21.5 0.0 2.1 2 0 0 2 2 2 1 PA14 domain Cadherin_5 PF17892.1 KXS17706.1 - 0.0003 20.7 7.4 0.015 15.2 1.5 2.8 2 0 0 2 2 2 2 Cadherin-like domain Cadherin PF00028.17 KXS17706.1 - 0.0012 19.2 1.3 0.23 11.9 0.0 3.3 4 0 0 4 4 4 1 Cadherin domain Cadherin_4 PF17803.1 KXS17706.1 - 0.012 16.2 21.2 0.046 14.3 6.0 3.1 3 1 0 3 3 3 0 Bacterial cadherin-like domain FG-GAP_2 PF14312.6 KXS17707.1 - 1.7e-05 24.9 3.7 4.4 7.6 0.0 5.6 6 0 0 6 6 6 3 FG-GAP repeat Lipase_C PF18067.1 KXS17707.1 - 0.039 14.5 0.5 0.66 10.6 0.0 3.0 3 1 1 4 4 4 0 Lipase C-terminal domain Acyl-CoA_dh_1 PF00441.24 KXS17708.1 - 1.7e-41 141.9 0.5 4e-41 140.7 0.1 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KXS17708.1 - 7.7e-36 123.2 0.1 1.4e-35 122.4 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KXS17708.1 - 1.6e-27 95.5 0.0 3.4e-27 94.5 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KXS17708.1 - 3.6e-13 50.0 0.0 7e-13 49.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 KXS17708.1 - 0.07 12.8 0.1 0.39 10.3 0.1 2.0 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal TLD PF07534.16 KXS17709.1 - 0.0018 18.5 0.0 0.0041 17.3 0.0 1.6 1 0 0 1 1 1 1 TLD Rep_fac-A_3 PF08661.11 KXS17710.1 - 5.6e-22 78.1 0.0 6.9e-22 77.8 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 DUF5500 PF17604.2 KXS17710.1 - 0.13 12.3 0.1 0.5 10.5 0.1 1.7 1 1 1 2 2 2 0 Family of unknown function (DUF5500) Abhydrolase_3 PF07859.13 KXS17711.1 - 3.5e-43 147.9 0.0 4.8e-43 147.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KXS17711.1 - 1.1e-09 37.7 0.0 1.6e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 KXS17711.1 - 0.0015 18.1 0.3 0.049 13.1 0.1 2.6 1 1 1 2 2 2 1 Prolyl oligopeptidase family COesterase PF00135.28 KXS17711.1 - 0.041 12.8 0.1 0.57 9.0 0.0 2.0 2 0 0 2 2 2 0 Carboxylesterase family SWIB PF02201.18 KXS17713.1 - 5.7e-09 35.7 0.0 1.1e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 SWIB/MDM2 domain Form_Nir_trans PF01226.17 KXS17714.1 - 5.8e-79 264.8 16.4 7.4e-79 264.4 16.4 1.1 1 0 0 1 1 1 1 Formate/nitrite transporter RhodobacterPufX PF11511.8 KXS17714.1 - 0.01 15.4 0.1 0.01 15.4 0.1 2.3 2 0 0 2 2 2 0 Intrinsic membrane protein PufX DUF1769 PF08588.10 KXS17715.1 - 0.0092 16.2 0.0 0.025 14.8 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) SH3_9 PF14604.6 KXS17717.1 - 1.4e-07 31.3 0.9 2.5e-07 30.4 0.9 1.4 1 0 0 1 1 1 1 Variant SH3 domain Shugoshin_N PF07558.11 KXS17717.1 - 0.014 15.3 1.9 0.11 12.3 0.3 2.2 1 1 1 2 2 2 0 Shugoshin N-terminal coiled-coil region SH3_1 PF00018.28 KXS17717.1 - 0.015 14.9 0.2 0.027 14.1 0.2 1.4 1 0 0 1 1 1 0 SH3 domain DivIC PF04977.15 KXS17717.1 - 0.017 14.9 0.2 0.11 12.3 0.2 2.0 1 1 1 2 2 2 0 Septum formation initiator MAD PF05557.13 KXS17717.1 - 0.019 13.4 0.0 0.024 13.0 0.0 1.2 1 0 0 1 1 1 0 Mitotic checkpoint protein SH3_2 PF07653.17 KXS17717.1 - 0.023 14.4 0.2 0.048 13.3 0.2 1.5 1 0 0 1 1 1 0 Variant SH3 domain TMCO5 PF14992.6 KXS17717.1 - 0.051 13.1 0.0 0.059 13.0 0.0 1.1 1 0 0 1 1 1 0 TMCO5 family ATG16 PF08614.11 KXS17717.1 - 0.056 13.7 1.2 0.078 13.2 1.2 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) bZIP_1 PF00170.21 KXS17717.1 - 0.062 13.4 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 bZIP transcription factor PspA_IM30 PF04012.12 KXS17717.1 - 0.067 12.8 0.0 0.094 12.3 0.0 1.2 1 0 0 1 1 1 0 PspA/IM30 family HrpB7 PF09486.10 KXS17717.1 - 0.069 13.5 0.2 1.2 9.6 0.2 2.0 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) bZIP_2 PF07716.15 KXS17717.1 - 0.073 13.2 0.4 1.3 9.1 0.2 2.2 1 1 1 2 2 2 0 Basic region leucine zipper DUF4614 PF15391.6 KXS17717.1 - 0.074 13.0 3.4 0.097 12.7 3.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Csm1_N PF18504.1 KXS17717.1 - 0.079 13.3 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 Csm1 N-terminal domain TMF_DNA_bd PF12329.8 KXS17717.1 - 0.088 12.8 0.5 0.19 11.7 0.1 1.8 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Macoilin PF09726.9 KXS17717.1 - 0.12 10.9 0.8 0.16 10.5 0.8 1.1 1 0 0 1 1 1 0 Macoilin family TSC22 PF01166.18 KXS17717.1 - 0.15 12.4 0.5 2.9 8.3 0.1 2.3 1 1 1 2 2 2 0 TSC-22/dip/bun family NinB PF05772.12 KXS17718.1 - 0.0024 17.7 0.1 0.013 15.3 0.9 1.9 2 0 0 2 2 2 1 NinB protein Spc7 PF08317.11 KXS17718.1 - 0.12 11.2 11.0 0.19 10.6 11.0 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein ERM PF00769.19 KXS17718.1 - 0.21 11.4 16.4 0.28 11.0 16.4 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DUF4140 PF13600.6 KXS17718.1 - 0.23 11.9 14.0 0.13 12.8 3.0 2.6 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) OmpH PF03938.14 KXS17718.1 - 0.28 11.5 13.5 0.49 10.7 13.5 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) FlxA PF14282.6 KXS17718.1 - 0.32 11.0 9.8 0.19 11.7 7.3 1.9 1 1 0 1 1 1 0 FlxA-like protein UPF0242 PF06785.11 KXS17718.1 - 0.43 10.7 9.4 0.6 10.2 9.4 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus ArAE_2_N PF10337.9 KXS17718.1 - 0.68 8.9 7.1 2.3 7.2 7.2 1.7 1 1 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal DUF4201 PF13870.6 KXS17718.1 - 0.89 9.3 12.8 2 8.1 11.9 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) DUF2721 PF11026.8 KXS17718.1 - 1 9.3 3.2 0.47 10.4 0.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) DUF4407 PF14362.6 KXS17718.1 - 1 8.7 9.3 1.3 8.4 9.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) KELK PF15796.5 KXS17718.1 - 1.7 9.2 18.1 0.2 12.2 0.9 2.4 1 1 1 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase YabA PF06156.13 KXS17718.1 - 2.1 9.0 10.3 4.5 8.0 5.0 2.3 1 1 1 2 2 2 0 Initiation control protein YabA FapA PF03961.13 KXS17718.1 - 6.5 5.2 6.8 22 3.5 5.5 1.8 1 1 1 2 2 2 0 Flagellar Assembly Protein A PRKG1_interact PF15898.5 KXS17718.1 - 6.5 7.7 13.5 7.1 7.6 12.4 1.7 1 1 0 1 1 1 0 cGMP-dependent protein kinase interacting domain Ccdc124 PF06244.12 KXS17719.1 - 1.5e-27 96.7 15.2 1.3e-25 90.4 15.2 2.9 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 124 /Oxs1 HMG_box PF00505.19 KXS17719.1 - 3.9e-05 24.0 0.2 3.9e-05 24.0 0.2 2.3 2 1 1 3 3 3 1 HMG (high mobility group) box YABBY PF04690.13 KXS17719.1 - 0.0063 17.1 0.1 0.0063 17.1 0.1 2.1 2 0 0 2 2 2 1 YABBY protein Levi_coat PF01819.17 KXS17719.1 - 0.32 11.0 1.3 2.8 8.0 0.1 2.4 2 0 0 2 2 2 0 Levivirus coat protein PTH2 PF01981.16 KXS17720.1 - 6.4e-18 65.1 0.1 7.5e-18 64.9 0.1 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 MtN3_slv PF03083.16 KXS17721.1 - 4.5e-30 103.5 7.5 3e-18 65.6 0.5 2.2 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange MPC PF03650.13 KXS17721.1 - 0.05 13.8 0.4 0.25 11.5 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial pyruvate carriers dCMP_cyt_deam_1 PF00383.23 KXS17722.1 - 2.2e-23 82.0 0.0 3.4e-23 81.4 0.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KXS17722.1 - 5.2e-20 71.6 0.0 6.6e-20 71.3 0.0 1.1 1 0 0 1 1 1 1 MafB19-like deaminase APOBEC4_like PF18774.1 KXS17722.1 - 0.0011 18.9 0.0 0.011 15.7 0.0 2.0 1 1 0 1 1 1 1 APOBEC4-like -AID/APOBEC-deaminase SNAD4 PF18750.1 KXS17722.1 - 0.0011 19.0 0.0 0.0065 16.6 0.0 1.9 2 0 0 2 2 2 1 Secreted Novel AID/APOBEC-like Deaminase 4 Bd3614-deam PF14439.6 KXS17722.1 - 0.007 16.4 0.2 0.021 14.9 0.2 1.9 1 1 0 1 1 1 1 Bd3614-like deaminase NAD1 PF18778.1 KXS17722.1 - 0.083 13.0 0.2 0.24 11.5 0.2 1.8 1 1 0 1 1 1 0 Novel AID APOBEC clade 1 APOBEC2 PF18772.1 KXS17722.1 - 0.099 12.7 0.1 0.24 11.4 0.1 1.7 1 1 0 1 1 1 0 APOBEC2 Transp_cyt_pur PF02133.15 KXS17723.1 - 8.7e-31 107.1 33.0 1.2e-30 106.7 33.0 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin PBP PF01161.20 KXS17724.1 - 1.1e-12 48.4 0.0 2.1e-12 47.5 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein HOOK PF05622.12 KXS17724.1 - 0.025 12.8 1.7 0.033 12.3 1.7 1.1 1 0 0 1 1 1 0 HOOK protein CCCAP PF15964.5 KXS17724.1 - 0.07 11.4 1.0 0.097 10.9 1.0 1.1 1 0 0 1 1 1 0 Centrosomal colon cancer autoantigen protein family Pyr_redox_2 PF07992.14 KXS17725.1 - 2e-16 60.1 0.0 4.5e-11 42.5 0.0 2.4 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KXS17725.1 - 6.8e-05 22.1 0.1 0.016 14.2 0.1 2.2 1 1 1 2 2 2 2 Lycopene cyclase protein NAD_binding_9 PF13454.6 KXS17725.1 - 0.00033 20.7 0.0 0.023 14.7 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 KXS17725.1 - 0.00052 20.5 0.4 0.68 10.5 0.1 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXS17725.1 - 0.00056 19.6 1.2 0.0023 17.6 0.3 2.3 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXS17725.1 - 0.0068 16.6 1.3 0.024 14.9 0.1 2.6 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 KXS17725.1 - 0.0096 14.8 0.1 0.067 12.0 0.1 2.3 3 1 0 3 3 3 1 Tryptophan halogenase Pyr_redox_3 PF13738.6 KXS17725.1 - 0.018 14.3 0.3 0.54 9.5 0.3 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXS17725.1 - 0.021 13.6 0.4 0.18 10.5 0.6 2.4 3 0 0 3 3 3 0 HI0933-like protein Thi4 PF01946.17 KXS17725.1 - 0.025 13.8 0.1 0.044 13.0 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Malic_M PF03949.15 KXS17725.1 - 0.11 11.7 0.3 11 5.3 0.2 2.1 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain FAD_binding_2 PF00890.24 KXS17725.1 - 0.14 11.2 1.1 0.25 10.3 1.1 1.4 1 0 0 1 1 1 0 FAD binding domain GIY-YIG PF01541.24 KXS17726.1 - 2.2e-14 53.5 0.1 3.3e-14 52.9 0.1 1.3 1 0 0 1 1 1 1 GIY-YIG catalytic domain DIOX_N PF14226.6 KXS17727.1 - 1.2e-22 80.9 0.0 2.2e-22 80.0 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KXS17727.1 - 5.7e-19 68.5 0.1 1.9e-18 66.8 0.1 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily CPSase_L_D2 PF02786.17 KXS17728.1 - 1.4e-73 246.9 0.0 2.4e-73 246.1 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 KXS17728.1 - 2.3e-47 160.1 0.0 6.4e-47 158.7 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KXS17728.1 - 4e-35 120.2 0.0 8e-35 119.2 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 KXS17728.1 - 3.1e-17 62.2 1.5 7.5e-17 60.9 0.7 2.1 2 0 0 2 2 2 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 KXS17728.1 - 8.4e-07 28.7 0.1 0.051 13.4 0.0 2.8 1 1 1 2 2 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.13 KXS17728.1 - 4.8e-06 26.3 0.0 9.7e-06 25.3 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KXS17728.1 - 6.1e-06 25.9 0.0 1.2e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.6 KXS17728.1 - 1.9e-05 25.3 0.1 0.0063 17.2 0.0 2.9 2 0 0 2 2 2 1 HlyD family secretion protein GARS_A PF01071.19 KXS17728.1 - 0.00017 21.4 0.0 0.00032 20.5 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GCV_H PF01597.19 KXS17728.1 - 0.009 15.9 0.1 0.018 14.9 0.1 1.4 1 0 0 1 1 1 1 Glycine cleavage H-protein RnfC_N PF13375.6 KXS17728.1 - 0.03 14.3 0.2 0.21 11.6 0.1 2.4 2 0 0 2 2 2 0 RnfC Barrel sandwich hybrid domain HlyD_D23 PF16576.5 KXS17728.1 - 0.04 13.1 0.1 6.8 5.8 0.0 2.3 1 1 1 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion zf-C2H2_aberr PF17017.5 KXS17729.1 - 0.0028 17.8 4.6 0.039 14.1 0.5 2.3 2 0 0 2 2 2 2 Aberrant zinc-finger zf-C2H2 PF00096.26 KXS17729.1 - 0.013 16.0 14.6 0.13 12.7 0.3 3.5 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXS17729.1 - 0.014 16.2 18.2 0.12 13.3 4.9 4.0 3 0 0 3 3 3 0 C2H2-type zinc finger zf-BED PF02892.15 KXS17729.1 - 0.7 10.0 9.1 4.7 7.3 0.1 2.7 2 0 0 2 2 2 0 BED zinc finger Mcm10 PF09332.11 KXS17729.1 - 7.6 5.9 6.4 13 5.1 6.4 1.3 1 0 0 1 1 1 0 Mcm10 replication factor WSD PF15613.6 KXS17730.1 - 0.0025 18.2 0.1 0.027 14.9 0.1 2.7 1 1 0 1 1 1 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif Ammonium_transp PF00909.21 KXS17731.1 - 1.1e-108 363.5 28.0 1.3e-108 363.3 28.0 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Tweety PF04906.13 KXS17731.1 - 0.65 8.6 2.2 0.7 8.5 0.3 1.8 2 0 0 2 2 2 0 Tweety ELO PF01151.18 KXS17732.1 - 5.1e-56 190.0 28.7 6.3e-56 189.7 28.7 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family RRM_1 PF00076.22 KXS17733.1 - 8.2e-15 54.4 0.0 1.6e-14 53.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Surp PF01805.20 KXS17733.1 - 4.9e-12 45.6 0.0 8.5e-12 44.9 0.0 1.4 1 0 0 1 1 1 1 Surp module CTD_bind PF04818.13 KXS17733.1 - 0.0019 19.0 0.0 0.0041 17.9 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase II-binding domain. RRM_5 PF13893.6 KXS17733.1 - 0.0028 17.3 0.0 0.0062 16.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_16 PF13191.6 KXS17733.1 - 0.26 11.7 1.5 0.63 10.4 0.2 2.2 3 0 0 3 3 3 0 AAA ATPase domain FancD2 PF14631.6 KXS17734.1 - 2.7e-128 429.4 0.0 7.4e-73 245.7 0.0 3.3 2 1 1 3 3 3 3 Fanconi anaemia protein FancD2 nuclease HEAT_2 PF13646.6 KXS17734.1 - 6.5e-06 26.4 2.4 2.4e-05 24.6 0.8 2.9 2 1 0 2 2 2 1 HEAT repeats FANCI_S4 PF14678.6 KXS17734.1 - 0.6 9.2 5.3 0.47 9.5 0.2 2.9 3 0 0 3 3 3 0 FANCI solenoid 4 Ank_2 PF12796.7 KXS17735.1 - 3.2e-47 159.0 0.2 1.4e-09 38.4 0.2 5.4 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXS17735.1 - 1.5e-36 124.3 5.9 3.5e-07 30.7 0.4 8.1 4 2 3 8 8 8 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXS17735.1 - 2.1e-32 110.7 16.2 1.7e-09 37.7 0.5 9.7 3 2 8 11 11 11 9 Ankyrin repeats (many copies) Ank PF00023.30 KXS17735.1 - 1.9e-30 104.0 11.1 1.9e-06 28.0 0.1 9.5 11 0 0 11 11 11 6 Ankyrin repeat Ank_3 PF13606.6 KXS17735.1 - 3.5e-29 97.6 5.9 0.00028 21.1 0.0 10.8 11 0 0 11 11 11 6 Ankyrin repeat NMT1 PF09084.11 KXS17735.1 - 0.13 12.2 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 NMT1/THI5 like Ank_2 PF12796.7 KXS17736.1 - 5.3e-15 55.8 0.0 7.6e-15 55.3 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXS17736.1 - 2.3e-14 52.1 1.4 6.9e-06 26.0 0.1 2.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 KXS17736.1 - 8.9e-14 51.7 1.0 7.9e-13 48.6 0.2 2.0 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 KXS17736.1 - 9.6e-14 51.1 6.6 4.5e-06 26.9 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 KXS17736.1 - 1.4e-09 38.0 1.8 4e-07 30.2 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) CBF PF03914.17 KXS17737.1 - 4.7e-44 150.4 0.1 2.1e-43 148.3 0.1 2.2 1 0 0 1 1 1 1 CBF/Mak21 family Radical_SAM PF04055.21 KXS17738.1 - 6.6e-14 52.6 0.1 2.1e-13 51.0 0.1 1.8 1 1 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 KXS17738.1 - 3.2e-12 46.9 0.0 1.5e-11 44.7 0.0 1.9 1 1 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 KXS17738.1 - 3.9e-05 23.8 0.0 0.072 13.2 0.1 2.4 2 0 0 2 2 2 2 4Fe-4S single cluster domain ABC_tran_CTD PF16326.5 KXS17740.1 - 0.0075 16.5 0.4 0.74 10.1 0.0 2.6 3 0 0 3 3 3 1 ABC transporter C-terminal domain HemX PF04375.14 KXS17740.1 - 0.023 14.0 0.4 0.034 13.4 0.4 1.1 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase Trimer_CC PF08954.11 KXS17740.1 - 0.052 13.1 0.9 0.37 10.4 0.9 2.6 1 0 0 1 1 1 0 Trimerisation motif BLOC1_2 PF10046.9 KXS17740.1 - 0.083 13.2 0.4 0.86 9.9 0.2 2.1 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SlyX PF04102.12 KXS17740.1 - 0.14 12.8 4.7 1.2 9.8 0.0 2.9 3 0 0 3 3 3 0 SlyX LPP PF04728.13 KXS17740.1 - 0.15 12.5 0.8 3.1 8.2 0.2 2.5 2 0 0 2 2 2 0 Lipoprotein leucine-zipper CLZ PF16526.5 KXS17740.1 - 0.28 11.6 1.7 3.4 8.1 0.3 2.5 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ADIP PF11559.8 KXS17740.1 - 0.42 10.7 3.9 4.8 7.3 0.7 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding CENP-Q PF13094.6 KXS17740.1 - 1.5 9.0 7.2 11 6.3 0.6 2.3 1 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit WD40 PF00400.32 KXS17742.1 - 9.6e-36 121.2 12.3 1.4e-05 25.7 0.0 8.8 7 1 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.7 KXS17742.1 - 8.1e-12 44.8 0.2 1.7e-11 43.8 0.2 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXS17742.1 - 3e-08 33.3 0.5 6.7e-08 32.2 0.1 1.8 2 0 0 2 2 2 1 F-box domain Nup160 PF11715.8 KXS17742.1 - 1e-06 27.7 0.5 0.0057 15.4 0.1 3.0 3 1 1 4 4 4 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 KXS17742.1 - 0.00013 22.2 0.1 3.7 7.9 0.0 5.0 3 2 3 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain F-box_4 PF15966.5 KXS17742.1 - 0.061 13.2 0.1 0.3 11.0 0.0 2.0 2 0 0 2 2 2 0 F-box Pyr_redox_2 PF07992.14 KXS17743.1 - 4.1e-24 85.3 0.3 8.2e-18 64.6 0.1 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXS17743.1 - 1.9e-15 57.1 0.9 5.8e-10 39.6 0.3 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXS17743.1 - 5.1e-08 32.5 0.0 1.2e-05 24.6 0.0 2.1 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KXS17743.1 - 1.1e-07 32.0 0.5 0.028 14.4 0.0 3.3 3 0 0 3 3 3 3 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KXS17743.1 - 8.9e-07 29.0 0.2 0.0018 18.4 0.0 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KXS17743.1 - 9e-07 28.4 0.4 6.5e-05 22.3 0.1 2.1 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KXS17743.1 - 1.2e-06 27.9 0.1 0.0047 16.0 0.0 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein DAO PF01266.24 KXS17743.1 - 2.3e-06 27.5 5.8 0.076 12.6 0.0 3.4 3 0 0 3 3 3 2 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KXS17743.1 - 3.1e-05 23.0 0.5 0.01 14.7 0.0 2.6 3 0 0 3 3 3 2 Tryptophan halogenase HI0933_like PF03486.14 KXS17743.1 - 0.00034 19.4 0.1 2.3 6.8 0.0 3.2 3 0 0 3 3 3 2 HI0933-like protein Shikimate_DH PF01488.20 KXS17743.1 - 0.015 15.4 0.2 2.1 8.4 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Malic_M PF03949.15 KXS17743.1 - 0.016 14.5 0.1 0.48 9.6 0.2 2.3 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain FAD_binding_3 PF01494.19 KXS17743.1 - 0.02 14.2 0.3 0.14 11.3 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain Inv-AAD PF18785.1 KXS17743.1 - 0.023 14.6 0.2 0.05 13.5 0.2 1.5 1 0 0 1 1 1 0 Invertebrate-AID/APOBEC-deaminase NAD_binding_7 PF13241.6 KXS17743.1 - 0.028 14.9 0.1 3.6 8.1 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding AnmK PF03702.14 KXS17743.1 - 0.034 13.3 0.0 14 4.6 0.0 2.8 2 1 1 3 3 3 0 Anhydro-N-acetylmuramic acid kinase Spermine_synth PF01564.17 KXS17743.1 - 0.041 13.3 0.1 3.3 7.1 0.0 2.2 2 0 0 2 2 2 0 Spermine/spermidine synthase domain FAD_binding_2 PF00890.24 KXS17743.1 - 0.071 12.2 2.0 1.7 7.6 0.1 2.3 2 0 0 2 2 2 0 FAD binding domain AlaDh_PNT_C PF01262.21 KXS17743.1 - 0.12 11.7 1.0 7.2 5.8 0.0 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 KXS17743.1 - 3.1 6.8 7.3 13 4.7 1.5 3.0 3 0 0 3 3 3 0 Glucose inhibited division protein A LRR_6 PF13516.6 KXS17744.1 - 8.3e-14 50.4 4.7 0.0024 17.8 0.0 5.8 7 0 0 7 7 7 3 Leucine Rich repeat LRR_4 PF12799.7 KXS17744.1 - 0.066 13.7 0.5 23 5.6 0.5 3.3 2 1 0 2 2 2 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXS17744.1 - 0.071 12.9 0.3 13 5.7 0.0 2.9 2 1 0 2 2 2 0 Leucine rich repeat ORC3_N PF07034.11 KXS17745.1 - 1e-39 136.6 0.0 2e-39 135.6 0.0 1.4 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus ORC_WH_C PF18137.1 KXS17745.1 - 4.1e-31 107.9 0.0 1.8e-30 105.8 0.0 2.1 2 0 0 2 2 2 1 Origin recognition complex winged helix C-terminal DUF2040 PF09745.9 KXS17746.1 - 8.3e-34 116.3 17.2 8.3e-34 116.3 17.2 3.2 2 2 0 2 2 2 1 Coiled-coil domain-containing protein 55 (DUF2040) HEAT_2 PF13646.6 KXS17747.1 - 6.3e-06 26.5 1.6 0.0052 17.1 0.1 4.2 4 0 0 4 4 4 2 HEAT repeats HEAT PF02985.22 KXS17747.1 - 0.0012 18.9 1.7 11 6.6 0.0 4.9 5 0 0 5 5 5 1 HEAT repeat Peptidase_S9 PF00326.21 KXS17749.1 - 4.6e-08 32.8 0.0 8.1e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KXS17749.1 - 0.0017 18.1 0.0 0.4 10.3 0.0 2.3 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXS17749.1 - 0.022 14.0 0.1 1.4 8.2 0.0 2.6 2 1 0 3 3 3 0 Serine aminopeptidase, S33 PhoPQ_related PF10142.9 KXS17749.1 - 0.029 13.0 0.0 0.046 12.4 0.0 1.2 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein KAP PF05804.12 KXS17751.1 - 5.9e-109 365.2 0.0 7.8e-62 209.4 0.0 3.8 3 1 0 3 3 3 3 Kinesin-associated protein (KAP) Cnd1 PF12717.7 KXS17751.1 - 0.074 13.1 0.0 0.73 9.9 0.0 2.4 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Lambda_CIII PF02061.16 KXS17751.1 - 3.4 7.8 4.4 15 5.7 0.1 3.2 3 0 0 3 3 3 0 Lambda Phage CIII ABC2_membrane PF01061.24 KXS17752.1 - 1.4e-22 80.1 12.4 2.3e-22 79.4 12.4 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 KXS17752.1 - 7.8e-22 78.3 0.0 1.2e-21 77.7 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_18 PF13238.6 KXS17752.1 - 0.008 16.7 0.0 0.015 15.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 KXS17752.1 - 0.016 14.3 0.1 0.027 13.5 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein ABC2_membrane_3 PF12698.7 KXS17752.1 - 0.018 14.1 14.2 0.016 14.3 13.0 1.4 1 1 0 1 1 1 0 ABC-2 family transporter protein AAA_16 PF13191.6 KXS17752.1 - 0.053 13.9 0.9 0.18 12.2 0.9 1.9 1 1 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 KXS17752.1 - 0.054 13.4 0.6 0.1 12.5 0.6 1.3 1 0 0 1 1 1 0 RsgA GTPase NACHT PF05729.12 KXS17752.1 - 0.067 13.1 0.1 0.12 12.3 0.1 1.4 1 0 0 1 1 1 0 NACHT domain AAA_22 PF13401.6 KXS17752.1 - 0.093 13.0 0.4 0.29 11.4 0.4 1.8 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KXS17752.1 - 0.16 12.4 0.0 0.26 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KXS17752.1 - 0.16 11.7 1.2 0.43 10.4 1.2 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KXS17752.1 - 0.2 11.8 0.1 0.38 10.8 0.1 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_28 PF13521.6 KXS17752.1 - 0.2 11.9 2.1 0.43 10.8 1.6 1.8 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 KXS17752.1 - 0.22 11.1 0.4 0.37 10.3 0.4 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_21 PF13304.6 KXS17752.1 - 0.47 10.2 2.6 1.6 8.4 0.5 2.1 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Hydrolase_4 PF12146.8 KXS17753.1 - 5.8e-15 55.2 0.1 4.6e-12 45.7 0.0 2.6 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KXS17753.1 - 2.8e-10 40.3 0.1 2e-08 34.2 0.1 2.2 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXS17753.1 - 4e-07 30.9 12.4 4e-07 30.9 12.4 2.1 2 1 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KXS17753.1 - 8.7e-06 25.3 0.0 3.2e-05 23.5 0.0 1.9 1 1 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 KXS17753.1 - 5.6e-05 22.8 0.0 0.00068 19.2 0.0 2.1 1 1 0 1 1 1 1 Dienelactone hydrolase family BAAT_C PF08840.11 KXS17753.1 - 0.00018 21.5 0.0 0.0067 16.4 0.0 2.3 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal AXE1 PF05448.12 KXS17753.1 - 0.00065 18.5 0.1 0.0013 17.5 0.1 1.4 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Esterase PF00756.20 KXS17753.1 - 0.004 16.8 0.0 0.0063 16.2 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.16 KXS17753.1 - 0.0042 16.9 0.0 0.077 12.8 0.0 2.3 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.7 KXS17753.1 - 0.035 13.9 0.0 0.27 11.0 0.0 2.3 3 0 0 3 3 3 0 Alpha/beta hydrolase family FSH1 PF03959.13 KXS17753.1 - 0.04 13.6 0.0 0.083 12.5 0.0 1.5 1 1 0 1 1 1 0 Serine hydrolase (FSH1) DUF818 PF05677.12 KXS17753.1 - 0.25 10.2 0.0 0.38 9.7 0.0 1.1 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) MCM PF00493.23 KXS17754.1 - 1e-104 348.5 0.0 1.6e-104 347.9 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KXS17754.1 - 1.5e-33 115.3 0.9 3.2e-33 114.3 0.9 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KXS17754.1 - 2e-21 76.2 3.0 7.2e-21 74.4 3.0 2.1 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KXS17754.1 - 9.9e-17 61.4 2.4 1.3e-16 61.1 0.6 2.2 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 KXS17754.1 - 3.2e-08 33.2 0.1 9.7e-06 25.1 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KXS17754.1 - 2.2e-06 27.7 0.0 2.2e-05 24.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_lid_2 PF17863.1 KXS17754.1 - 0.0077 16.0 0.3 0.022 14.6 0.3 1.8 1 0 0 1 1 1 1 AAA lid domain AAA_3 PF07726.11 KXS17754.1 - 0.04 13.8 0.1 0.14 12.0 0.1 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KXS17754.1 - 0.11 12.9 0.1 0.11 12.9 0.1 3.5 3 2 0 3 3 3 0 AAA ATPase domain Sigma54_activat PF00158.26 KXS17754.1 - 0.13 12.0 0.0 0.52 10.0 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain HORMA PF02301.18 KXS17755.1 - 1.3e-22 80.4 0.0 1.7e-22 80.1 0.0 1.1 1 0 0 1 1 1 1 HORMA domain bacHORMA_2 PF18173.1 KXS17755.1 - 0.04 13.8 0.0 0.064 13.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial HORMA domain 2 DUF5503 PF17607.2 KXS17755.1 - 0.054 13.8 0.0 0.57 10.5 0.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5503) zf-rbx1 PF12678.7 KXS17756.1 - 4.2e-25 87.8 13.1 4.2e-25 87.8 13.1 1.5 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KXS17756.1 - 2.1e-17 63.0 9.9 2.8e-17 62.5 9.9 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 KXS17756.1 - 2.4e-06 27.8 14.6 8.7e-05 22.8 14.6 2.3 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KXS17756.1 - 0.0014 18.4 11.8 0.025 14.4 11.8 2.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXS17756.1 - 0.003 17.4 14.8 0.0046 16.8 9.3 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KXS17756.1 - 0.13 12.1 10.9 0.4 10.6 4.6 2.6 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KXS17756.1 - 0.29 10.9 15.8 26 4.7 15.8 2.5 1 1 0 1 1 1 0 RING-like zinc finger zf-RING_UBOX PF13445.6 KXS17756.1 - 0.45 10.6 7.7 1.7 8.8 7.7 2.0 1 1 0 1 1 1 0 RING-type zinc-finger FANCL_C PF11793.8 KXS17756.1 - 0.55 10.4 9.4 3 8.1 9.6 1.9 1 1 1 2 2 2 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 KXS17756.1 - 0.63 9.7 14.9 0.16 11.6 4.8 2.3 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type Methyltransf_10 PF05971.12 KXS17757.1 - 1.1e-59 202.2 0.0 3.7e-59 200.5 0.0 1.7 1 1 0 1 1 1 1 RNA methyltransferase PrmA PF06325.13 KXS17757.1 - 0.0033 16.9 0.0 0.0049 16.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KXS17757.1 - 0.019 14.5 0.0 0.048 13.2 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_31 PF13847.6 KXS17757.1 - 0.17 11.7 0.0 0.25 11.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Syja_N PF02383.18 KXS17758.1 - 1.5e-89 300.5 0.3 1.9e-89 300.2 0.3 1.1 1 0 0 1 1 1 1 SacI homology domain LON_substr_bdg PF02190.16 KXS17759.1 - 3.3e-14 53.3 0.0 5.5e-14 52.5 0.0 1.3 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain zf-RING_UBOX PF13445.6 KXS17759.1 - 4.2e-13 49.1 21.4 1.6e-09 37.6 3.9 3.2 3 1 0 3 3 3 2 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KXS17759.1 - 5.2e-12 45.7 22.2 3.9e-08 33.3 2.8 3.2 3 0 0 3 3 3 2 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 KXS17759.1 - 2.7e-09 36.7 3.1 2.7e-09 36.7 3.1 3.3 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KXS17759.1 - 9.3e-09 35.0 18.0 0.00011 22.0 2.7 3.4 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXS17759.1 - 1.3e-06 28.1 22.5 3.3e-06 26.9 2.8 3.3 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXS17759.1 - 4e-06 27.1 19.9 0.00013 22.2 2.4 3.6 3 0 0 3 3 3 2 Ring finger domain zf-RING_5 PF14634.6 KXS17759.1 - 5e-05 23.2 21.1 0.00018 21.4 2.2 3.7 3 1 1 4 4 4 2 zinc-RING finger domain zf-RING_10 PF16685.5 KXS17759.1 - 0.0023 18.1 3.2 0.0023 18.1 3.2 2.5 2 0 0 2 2 2 1 zinc RING finger of MSL2 U-box PF04564.15 KXS17759.1 - 0.05 13.8 0.5 0.19 11.9 0.0 2.2 2 0 0 2 2 2 0 U-box domain Fer2 PF00111.27 KXS17759.1 - 0.24 11.4 4.8 14 5.8 0.1 3.1 3 1 0 3 3 3 0 2Fe-2S iron-sulfur cluster binding domain Peptidase_M54 PF07998.11 KXS17760.1 - 9.1e-18 64.9 0.0 1.1e-17 64.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M54 Reprolysin_4 PF13583.6 KXS17760.1 - 0.0037 16.9 0.0 0.0048 16.6 0.0 1.1 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 KXS17760.1 - 0.0054 16.6 0.0 0.0054 16.6 0.0 1.2 1 0 0 1 1 1 1 Matrixin Reprolysin_3 PF13582.6 KXS17760.1 - 0.017 15.7 0.0 0.022 15.3 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 KXS17760.1 - 0.019 15.1 0.0 0.023 14.9 0.0 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12 Metallopep PF12044.8 KXS17760.1 - 0.085 11.4 0.6 0.12 11.0 0.6 1.1 1 0 0 1 1 1 0 Putative peptidase family Reprolysin_2 PF13574.6 KXS17760.1 - 0.14 12.0 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like MHB PF16525.5 KXS17761.1 - 0.0091 16.2 0.0 0.0091 16.2 0.0 1.2 1 0 0 1 1 1 1 Haemophore, haem-binding CotJB PF12652.7 KXS17761.1 - 0.04 14.1 0.1 0.044 14.0 0.1 1.2 1 0 0 1 1 1 0 CotJB protein Hen1_L PF12623.7 KXS17761.1 - 0.075 12.1 0.1 0.34 9.9 0.1 1.8 1 1 1 2 2 2 0 RNA repair, ligase-Pnkp-associating, region of Hen1 RIIa PF02197.17 KXS17761.1 - 0.078 12.7 0.1 0.4 10.4 0.0 1.9 1 1 1 2 2 2 0 Regulatory subunit of type II PKA R-subunit Peptidase_S8 PF00082.22 KXS17762.1 - 3.6e-44 151.2 3.4 4.5e-44 150.9 3.4 1.1 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 KXS17762.1 - 2.3e-20 72.4 0.0 3.9e-20 71.7 0.0 1.4 1 0 0 1 1 1 1 Proprotein convertase P-domain Cul7 PF11515.8 KXS17762.1 - 0.041 14.2 0.0 1.6 9.0 0.0 2.3 2 0 0 2 2 2 0 Mouse development and cellular proliferation protein Cullin-7 RPEL PF02755.15 KXS17763.1 - 6.1e-21 73.4 3.8 2.4e-06 27.1 0.1 3.4 3 0 0 3 3 3 3 RPEL repeat ChlI PF13541.6 KXS17763.1 - 0.083 12.7 0.1 0.12 12.3 0.1 1.3 1 0 0 1 1 1 0 Subunit ChlI of Mg-chelatase DUF3519 PF12033.8 KXS17763.1 - 0.11 12.9 0.8 3.8 8.0 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3519) 14-3-3 PF00244.20 KXS17764.1 - 3.9e-108 360.1 4.7 4.5e-108 359.9 4.7 1.0 1 0 0 1 1 1 1 14-3-3 protein Peptidase_C98 PF15499.6 KXS17764.1 - 0.055 12.9 0.1 0.081 12.4 0.1 1.3 1 0 0 1 1 1 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Syja_N PF02383.18 KXS17766.1 - 9.7e-77 258.4 0.0 1.9e-76 257.4 0.0 1.5 1 0 0 1 1 1 1 SacI homology domain DUF5638 PF18688.1 KXS17766.1 - 0.099 13.0 0.2 0.31 11.4 0.2 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5638) Peptidase_C65 PF10275.9 KXS17767.1 - 5e-52 176.8 0.0 5.8e-52 176.6 0.0 1.0 1 0 0 1 1 1 1 Peptidase C65 Otubain CENP-Q PF13094.6 KXS17767.1 - 0.16 12.1 0.4 0.25 11.5 0.4 1.2 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DLIC PF05783.11 KXS17768.1 - 0.00025 20.0 0.0 0.0039 16.1 0.0 2.0 1 1 1 2 2 2 1 Dynein light intermediate chain (DLIC) Roc PF08477.13 KXS17768.1 - 0.0026 17.9 0.0 0.006 16.8 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 KXS17768.1 - 0.014 15.3 0.0 0.042 13.8 0.0 1.7 2 0 0 2 2 2 0 RsgA GTPase AAA_7 PF12775.7 KXS17768.1 - 0.069 12.7 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 KXS17768.1 - 0.073 13.5 0.1 0.23 11.8 0.1 2.1 2 1 0 2 2 2 0 AAA ATPase domain Arf PF00025.21 KXS17768.1 - 0.12 11.9 0.1 13 5.2 0.1 2.2 2 0 0 2 2 2 0 ADP-ribosylation factor family Zeta_toxin PF06414.12 KXS17768.1 - 0.17 11.2 0.0 0.27 10.5 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin TMF_TATA_bd PF12325.8 KXS17769.1 - 1.4e-28 99.4 7.7 1.4e-28 99.4 7.7 6.8 2 1 5 7 7 7 1 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.8 KXS17769.1 - 1.7e-05 24.7 14.3 1.7e-05 24.7 14.3 8.3 6 3 2 9 9 9 2 TATA element modulatory factor 1 DNA binding CENP-F_leu_zip PF10473.9 KXS17769.1 - 0.0009 19.3 12.6 0.0009 19.3 12.6 5.4 3 1 2 5 5 5 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Takusan PF04822.13 KXS17769.1 - 7.4 6.5 9.0 0.095 12.6 0.5 2.3 2 0 0 2 2 2 0 Takusan Baculo_PEP_C PF04513.12 KXS17769.1 - 9.5 6.3 16.5 0.8 9.7 0.1 4.5 4 1 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Coq4 PF05019.13 KXS17770.1 - 1.8e-92 308.7 0.0 2.1e-92 308.4 0.0 1.1 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 SCO1-SenC PF02630.14 KXS17771.1 - 9.9e-48 161.5 0.0 1.4e-47 160.9 0.0 1.2 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 KXS17771.1 - 2.7e-05 24.1 0.0 0.00014 21.8 0.0 2.2 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 KXS17771.1 - 0.00068 19.9 0.0 0.0016 18.7 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin-like Homeodomain PF00046.29 KXS17772.1 - 0.00024 20.9 1.4 0.00049 19.9 1.4 1.5 1 0 0 1 1 1 1 Homeodomain DUF5476 PF17570.2 KXS17772.1 - 0.36 11.3 2.8 1.4 9.4 2.8 2.1 1 0 0 1 1 1 0 Family of unknown function (DUF5476) TPR_1 PF00515.28 KXS17773.1 - 2.9e-47 156.6 9.2 9.9e-08 31.5 0.0 9.9 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_2 PF07719.17 KXS17773.1 - 6.8e-43 141.3 9.0 1.2e-05 25.0 0.0 10.1 10 1 0 10 10 10 8 Tetratricopeptide repeat TPR_11 PF13414.6 KXS17773.1 - 5e-35 118.9 0.0 4.8e-07 29.3 0.0 8.3 5 1 4 9 9 9 5 TPR repeat TPR_8 PF13181.6 KXS17773.1 - 1.9e-30 102.5 10.8 0.00041 20.3 0.1 9.2 10 0 0 10 10 9 6 Tetratricopeptide repeat TPR_16 PF13432.6 KXS17773.1 - 4.3e-27 94.5 0.2 1.9e-07 31.6 0.0 6.4 5 2 1 6 6 6 5 Tetratricopeptide repeat TPR_17 PF13431.6 KXS17773.1 - 6.4e-27 92.0 5.0 0.00026 21.2 0.0 8.2 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_14 PF13428.6 KXS17773.1 - 3.2e-24 83.5 2.2 0.013 16.3 0.2 9.0 2 2 7 9 9 9 7 Tetratricopeptide repeat TPR_19 PF14559.6 KXS17773.1 - 3.5e-23 81.9 4.0 7.6e-06 26.4 0.0 5.0 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_12 PF13424.6 KXS17773.1 - 4.4e-17 62.1 7.8 0.00081 19.6 0.0 7.1 5 2 1 7 7 6 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KXS17773.1 - 1.9e-15 56.8 0.4 0.0003 20.9 0.0 3.6 1 1 2 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 KXS17773.1 - 2.4e-15 56.5 2.9 9e-06 25.8 0.0 5.9 3 1 4 7 7 7 3 Tetratricopeptide repeat TPR_6 PF13174.6 KXS17773.1 - 5.5e-11 42.4 12.9 0.11 13.2 0.0 8.5 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_7 PF13176.6 KXS17773.1 - 9.1e-10 37.9 3.4 0.21 11.7 0.1 7.4 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_15 PF13429.6 KXS17773.1 - 1.2e-08 34.5 1.6 0.14 11.3 0.0 3.9 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 KXS17773.1 - 3.7e-08 33.0 8.7 1.5 8.8 0.6 6.4 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_21 PF09976.9 KXS17773.1 - 8.4e-08 32.2 2.4 0.22 11.2 0.7 3.5 2 2 1 3 3 3 3 Tetratricopeptide repeat-like domain TPR_MalT PF17874.1 KXS17773.1 - 5.8e-07 29.2 0.1 0.0067 15.8 0.7 3.1 1 1 0 3 3 3 2 MalT-like TPR region NARP1 PF12569.8 KXS17773.1 - 4.8e-06 25.8 1.2 0.32 9.9 0.2 3.5 1 1 0 3 3 3 2 NMDA receptor-regulated protein 1 TPR_20 PF14561.6 KXS17773.1 - 3.8e-05 23.9 2.4 1.7 9.1 0.0 4.3 3 1 2 5 5 5 1 Tetratricopeptide repeat SHNi-TPR PF10516.9 KXS17773.1 - 5e-05 22.7 0.5 0.058 12.9 0.0 3.5 3 0 0 3 3 3 1 SHNi-TPR FAT PF02259.23 KXS17773.1 - 0.00047 19.5 0.0 0.092 11.9 0.6 2.4 1 1 0 2 2 2 1 FAT domain TPR_4 PF07721.14 KXS17773.1 - 0.0072 16.9 0.2 20 6.2 0.0 4.9 5 1 0 5 5 4 0 Tetratricopeptide repeat DUF3808 PF10300.9 KXS17773.1 - 0.014 14.2 1.1 0.55 8.9 0.6 2.6 2 1 2 4 4 4 0 Protein of unknown function (DUF3808) PknG_TPR PF16918.5 KXS17773.1 - 0.022 13.5 0.0 2.5 6.8 0.0 2.4 2 1 1 3 3 3 0 Protein kinase G tetratricopeptide repeat BTAD PF03704.17 KXS17773.1 - 0.028 14.9 1.5 7.9 6.9 0.0 3.6 2 1 2 4 4 4 0 Bacterial transcriptional activator domain Mad3_BUB1_I PF08311.12 KXS17773.1 - 0.039 13.9 4.7 0.13 12.2 0.7 3.5 4 1 0 4 4 4 0 Mad3/BUB1 homology region 1 YfdX PF10938.8 KXS17773.1 - 0.19 11.7 5.0 6.2 6.8 0.0 4.4 4 1 0 4 4 4 0 YfdX protein Nup84_Nup100 PF04121.13 KXS17774.1 - 1.3e-117 393.8 0.1 2e-117 393.2 0.1 1.2 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 Oxysterol_BP PF01237.18 KXS17775.1 - 7.5e-120 400.2 0.1 1.5e-119 399.2 0.1 1.5 1 1 0 1 1 1 1 Oxysterol-binding protein DHFR_2 PF06442.11 KXS17775.1 - 0.16 11.8 0.0 0.4 10.6 0.0 1.6 1 0 0 1 1 1 0 R67 dihydrofolate reductase SH3_9 PF14604.6 KXS17776.1 - 2.5e-10 40.1 0.0 6.3e-10 38.8 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXS17776.1 - 5.8e-06 25.8 0.0 5.8e-06 25.8 0.0 1.8 2 0 0 2 2 1 1 SH3 domain Ank_5 PF13857.6 KXS17776.1 - 0.00094 19.4 0.0 0.0038 17.5 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 KXS17776.1 - 0.0027 18.1 0.0 0.062 13.8 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 KXS17776.1 - 0.015 15.8 0.0 0.33 11.7 0.0 3.1 4 0 0 4 4 3 0 Ankyrin repeat Ank_2 PF12796.7 KXS17776.1 - 0.019 15.5 0.0 0.089 13.4 0.0 2.1 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) GCP_N_terminal PF17681.1 KXS17776.1 - 0.11 12.1 3.4 0.63 9.6 0.4 2.3 2 0 0 2 2 2 0 Gamma tubulin complex component N-terminal TRAF_BIRC3_bd PF16673.5 KXS17776.1 - 0.13 12.1 28.7 0.33 10.8 1.6 6.3 5 2 0 5 5 5 0 TNF receptor-associated factor BIRC3 binding domain Baculo_PEP_C PF04513.12 KXS17776.1 - 0.55 10.3 6.6 1.2 9.2 0.2 3.5 2 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fib_alpha PF08702.10 KXS17776.1 - 1.8 8.7 25.8 1.4 9.1 5.4 4.4 1 1 2 4 4 4 0 Fibrinogen alpha/beta chain family HSBP1 PF06825.12 KXS17776.1 - 2.2 8.2 9.0 0.42 10.5 0.4 3.7 4 0 0 4 4 4 0 Heat shock factor binding protein 1 DUF3450 PF11932.8 KXS17776.1 - 4 6.7 40.2 1.3 8.3 0.2 4.9 2 1 3 5 5 5 0 Protein of unknown function (DUF3450) TINF2_N PF14973.6 KXS17776.1 - 4.5 7.6 8.5 0.96 9.8 1.4 2.7 1 1 1 2 2 2 0 TERF1-interacting nuclear factor 2 N-terminus FlaC_arch PF05377.11 KXS17776.1 - 7.7 7.0 18.5 3.4 8.1 0.3 5.8 6 0 0 6 6 5 0 Flagella accessory protein C (FlaC) CALCOCO1 PF07888.11 KXS17776.1 - 9.1 5.0 57.1 0.033 13.1 22.4 2.3 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like Phage_GP20 PF06810.11 KXS17776.1 - 9.6 6.0 31.7 0.29 10.9 0.9 5.1 2 2 3 5 5 5 0 Phage minor structural protein GP20 PCI PF01399.27 KXS17777.1 - 2e-11 44.3 1.1 7.5e-11 42.5 0.2 2.5 2 0 0 2 2 2 1 PCI domain Paf67 PF10255.9 KXS17778.1 - 2e-160 534.2 3.9 2.3e-160 534.0 3.9 1.0 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.17 KXS17778.1 - 0.13 12.4 0.0 0.34 11.1 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat Sulfate_transp PF00916.20 KXS17779.1 - 6e-55 186.5 23.9 9.6e-55 185.9 23.9 1.3 1 0 0 1 1 1 1 Sulfate permease family cNMP_binding PF00027.29 KXS17779.1 - 3.2e-17 62.4 0.0 7e-17 61.3 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.21 KXS17779.1 - 5.2e-17 61.6 0.1 1.2e-16 60.4 0.0 1.6 2 0 0 2 2 2 1 STAS domain STAS_2 PF13466.6 KXS17779.1 - 0.00077 19.8 0.0 0.0017 18.7 0.0 1.6 1 0 0 1 1 1 1 STAS domain DUF3188 PF11384.8 KXS17779.1 - 0.43 10.3 5.2 17 5.2 0.0 3.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3188) Tubulin PF00091.25 KXS17780.1 - 1.3e-52 178.9 0.0 1.8e-52 178.4 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KXS17780.1 - 3.5e-21 75.7 0.0 6.8e-21 74.7 0.0 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_2 PF13809.6 KXS17780.1 - 0.041 13.1 0.0 0.053 12.7 0.0 1.2 1 0 0 1 1 1 0 Tubulin like DUF1731 PF08338.11 KXS17780.1 - 0.19 11.6 0.1 21 5.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) CNH PF00780.22 KXS17781.1 - 5.5e-20 72.1 0.0 6.9e-20 71.8 0.0 1.1 1 0 0 1 1 1 1 CNH domain ANAPC4_WD40 PF12894.7 KXS17781.1 - 0.024 14.9 0.0 0.1 12.9 0.0 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain Macro_2 PF14519.6 KXS17781.1 - 0.077 12.3 0.0 0.35 10.2 0.0 1.8 2 0 0 2 2 2 0 Macro-like domain Pkinase PF00069.25 KXS17782.1 - 1.7e-57 194.8 0.0 2.1e-57 194.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS17782.1 - 3.4e-43 147.8 0.0 4e-43 147.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXS17782.1 - 4.3e-07 29.1 0.0 5.9e-07 28.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase ABC1 PF03109.16 KXS17782.1 - 0.00015 21.9 0.0 0.00029 21.0 0.0 1.5 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 KXS17782.1 - 0.0022 18.0 0.1 0.6 10.0 0.0 2.5 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.6 KXS17782.1 - 0.0064 15.9 0.0 0.016 14.5 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 KXS17782.1 - 0.16 10.9 0.0 1.2 8.0 0.0 1.9 1 1 0 1 1 1 0 Haspin like kinase domain Lipase_GDSL PF00657.22 KXS17783.1 - 4.6e-10 39.8 0.0 6.4e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 KXS17783.1 - 0.00037 20.9 0.4 0.0098 16.3 0.4 2.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family DNA_ligase_OB_2 PF14743.6 KXS17784.1 - 9.9e-30 102.4 0.3 1.8e-29 101.5 0.3 1.5 1 0 0 1 1 1 1 DNA ligase OB-like domain DNA_ligase_A_M PF01068.21 KXS17784.1 - 1.2e-15 57.7 0.0 4.6e-15 55.8 0.0 1.9 1 1 0 1 1 1 1 ATP dependent DNA ligase domain zf-CCHH PF10283.9 KXS17784.1 - 7e-14 51.5 2.2 1.4e-13 50.6 2.2 1.5 1 0 0 1 1 1 1 PBZ domain RNA_ligase PF09414.10 KXS17784.1 - 9.9e-07 29.2 0.0 2.5e-06 27.9 0.0 1.6 1 1 0 1 1 1 1 RNA ligase LSM PF01423.22 KXS17785.1 - 1.2e-16 60.2 0.0 1.6e-16 59.7 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KXS17785.1 - 0.026 14.7 0.0 0.036 14.2 0.0 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain ThiF PF00899.21 KXS17786.1 - 3.2e-101 337.8 0.0 4.1e-69 232.6 0.0 2.3 2 1 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 KXS17786.1 - 5.6e-96 321.3 0.4 8.9e-96 320.7 0.4 1.3 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_UFD PF09358.10 KXS17786.1 - 9.2e-35 119.2 0.7 2.5e-34 117.9 0.2 2.0 2 0 0 2 2 2 1 Ubiquitin fold domain E1_FCCH PF16190.5 KXS17786.1 - 8e-30 102.8 0.9 1.6e-29 101.8 0.3 1.9 2 0 0 2 2 2 1 Ubiquitin-activating enzyme E1 FCCH domain E1_4HB PF16191.5 KXS17786.1 - 9.1e-23 80.2 1.2 1.5e-22 79.6 0.3 1.9 2 0 0 2 2 2 1 Ubiquitin-activating enzyme E1 four-helix bundle ANAPC2 PF08672.11 KXS17786.1 - 0.15 12.6 0.0 11 6.6 0.1 3.0 3 0 0 3 3 3 0 Anaphase promoting complex (APC) subunit 2 V-ATPase_C PF03223.15 KXS17787.1 - 2.1e-134 448.6 10.0 2.3e-134 448.5 10.0 1.0 1 0 0 1 1 1 1 V-ATPase subunit C PP2C PF00481.21 KXS17788.1 - 2e-32 112.9 0.0 2.4e-32 112.6 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 KXS17788.1 - 0.00038 20.1 0.0 0.0008 19.1 0.0 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 KXS17788.1 - 0.036 14.0 0.0 1.1 9.1 0.0 2.2 2 0 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) D123 PF07065.14 KXS17789.1 - 8.9e-97 323.9 0.1 1e-96 323.7 0.1 1.0 1 0 0 1 1 1 1 D123 R2K_2 PF18299.1 KXS17789.1 - 0.032 14.1 0.0 0.068 13.0 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain, R2K clade family 2 DUF4393 PF14337.6 KXS17789.1 - 0.14 12.0 0.0 0.34 10.7 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4393) eIF-5_eIF-2B PF01873.17 KXS17790.1 - 2.8e-41 140.0 0.0 4e-41 139.6 0.0 1.1 1 0 0 1 1 1 1 Domain found in IF2B/IF5 TF_Zn_Ribbon PF08271.12 KXS17790.1 - 0.016 14.7 0.2 0.036 13.6 0.2 1.7 1 0 0 1 1 1 0 TFIIB zinc-binding IF2_N PF04760.15 KXS17790.1 - 0.028 14.2 0.0 0.055 13.3 0.0 1.4 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region zinc_ribbon_6 PF14599.6 KXS17790.1 - 0.1 12.7 0.8 5.6 7.0 0.3 2.3 2 0 0 2 2 2 0 Zinc-ribbon Zn-ribbon_8 PF09723.10 KXS17790.1 - 0.11 12.6 0.2 0.21 11.7 0.2 1.5 1 0 0 1 1 1 0 Zinc ribbon domain zinc_ribbon_4 PF13717.6 KXS17790.1 - 0.39 10.7 3.8 2.1 8.4 0.1 3.0 3 0 0 3 3 3 0 zinc-ribbon domain zf-HYPF PF07503.12 KXS17790.1 - 1.8 8.4 4.3 5.1 7.0 2.6 2.5 2 1 1 3 3 3 0 HypF finger PDH PF02153.17 KXS17791.1 - 2.3e-13 49.8 0.0 3.2e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase F420_oxidored PF03807.17 KXS17791.1 - 2.1e-06 28.2 0.0 4.3e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 KXS17791.1 - 0.0025 18.0 0.0 0.0045 17.2 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.16 KXS17791.1 - 0.0052 16.4 0.0 0.01 15.5 0.0 1.6 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.20 KXS17791.1 - 0.059 13.4 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 KXS17791.1 - 0.081 12.8 0.0 0.23 11.3 0.0 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 KXS17791.1 - 0.1 11.9 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HEAT_2 PF13646.6 KXS17792.1 - 1.1e-28 99.5 4.4 1.7e-06 28.3 0.2 8.8 5 3 5 10 10 10 7 HEAT repeats HEAT_EZ PF13513.6 KXS17792.1 - 6e-26 90.5 15.3 1.1e-07 32.2 0.3 11.4 10 2 1 12 12 12 3 HEAT-like repeat HEAT PF02985.22 KXS17792.1 - 1.5e-25 87.1 9.4 5.3e-06 26.2 0.1 12.2 13 0 0 13 13 11 3 HEAT repeat Cnd1 PF12717.7 KXS17792.1 - 1.2e-13 51.4 0.1 8.2e-07 29.2 0.0 5.1 4 2 1 5 5 5 3 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 KXS17792.1 - 7.2e-12 45.7 0.3 0.0018 18.9 0.0 7.0 7 1 1 8 8 8 3 Vacuolar 14 Fab1-binding region IBN_N PF03810.19 KXS17792.1 - 2.4e-09 37.0 0.0 8.8e-09 35.2 0.0 2.1 1 0 0 1 1 1 1 Importin-beta N-terminal domain Adaptin_N PF01602.20 KXS17792.1 - 6.8e-09 34.8 0.0 0.00015 20.5 0.0 4.1 3 1 0 3 3 3 2 Adaptin N terminal region Arm PF00514.23 KXS17792.1 - 1e-06 28.5 5.2 1.9 8.7 0.0 6.9 7 0 0 7 7 6 2 Armadillo/beta-catenin-like repeat IFRD PF05004.13 KXS17792.1 - 1.5e-06 27.6 0.1 0.044 12.9 0.0 4.1 4 1 0 4 4 4 2 Interferon-related developmental regulator (IFRD) RTP1_C1 PF10363.9 KXS17792.1 - 9.7e-06 25.7 0.3 0.15 12.2 0.0 5.0 5 1 0 5 5 5 1 Required for nuclear transport of RNA pol II C-terminus 1 MMS19_C PF12460.8 KXS17792.1 - 2.6e-05 23.5 0.0 0.066 12.3 0.0 4.6 3 2 1 5 5 5 2 RNAPII transcription regulator C-terminal UME PF08064.13 KXS17792.1 - 2.7e-05 24.0 0.0 1.3 8.9 0.0 4.8 4 0 0 4 4 4 1 UME (NUC010) domain ParcG PF10274.9 KXS17792.1 - 6.8e-05 23.1 0.0 0.0021 18.2 0.0 3.1 3 0 0 3 3 2 1 Parkin co-regulated protein CLASP_N PF12348.8 KXS17792.1 - 0.00018 21.2 0.0 1.1 8.7 0.0 5.0 5 1 1 6 6 6 1 CLASP N terminal DUF3385 PF11865.8 KXS17792.1 - 0.00018 21.5 1.2 2.2 8.1 0.0 5.4 4 3 2 6 6 5 1 Domain of unknown function (DUF3385) BP28CT PF08146.12 KXS17792.1 - 0.00054 19.8 0.1 0.32 10.8 0.0 4.2 3 1 0 3 3 3 1 BP28CT (NUC211) domain Tti2 PF10521.9 KXS17792.1 - 0.00089 18.9 0.1 3.4 7.1 0.0 4.4 3 2 1 4 4 4 1 Tti2 family DRIM PF07539.12 KXS17792.1 - 0.0038 15.6 0.1 2.4 6.3 0.0 3.9 4 0 0 4 4 4 1 Down-regulated in metastasis Sec7_N PF12783.7 KXS17792.1 - 0.0074 16.2 0.0 0.062 13.2 0.0 2.6 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Gcn1_N PF12074.8 KXS17792.1 - 0.047 13.0 0.0 4.9 6.4 0.0 3.4 3 1 0 3 3 3 0 Generalcontrol nonderepressible 1 (Gcn1) N-terminal PUL PF08324.11 KXS17792.1 - 0.09 12.0 4.8 7.4 5.7 0.0 4.2 5 0 0 5 5 5 0 PUL domain Ipi1_N PF12333.8 KXS17792.1 - 0.18 12.4 0.0 3.8 8.2 0.0 3.1 3 0 0 3 3 2 0 Rix1 complex component involved in 60S ribosome maturation Homeodomain PF00046.29 KXS17793.1 - 7.8e-17 60.9 0.3 2e-16 59.5 0.3 1.8 1 0 0 1 1 1 1 Homeodomain V_ATPase_I_N PF18670.1 KXS17793.1 - 0.1 13.0 0.0 0.25 11.8 0.0 1.6 1 0 0 1 1 1 0 V-type ATPase subunit I, N-terminal domain GN3L_Grn1 PF08701.11 KXS17794.1 - 6.4e-20 71.0 16.6 1.1e-19 70.3 16.6 1.4 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.23 KXS17794.1 - 9.5e-17 61.1 0.2 1.2e-13 51.1 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 KXS17794.1 - 8e-09 35.2 0.2 3.9e-06 26.5 0.0 2.2 2 0 0 2 2 2 2 Ferrous iron transport protein B GTP_EFTU PF00009.27 KXS17794.1 - 1.9e-05 24.3 0.0 0.00036 20.1 0.0 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KXS17794.1 - 2.8e-05 24.1 1.1 0.0044 16.9 1.1 2.4 1 1 0 1 1 1 1 RsgA GTPase Dynamin_N PF00350.23 KXS17794.1 - 0.00081 19.5 0.9 0.089 12.9 0.4 3.0 2 1 1 3 3 3 1 Dynamin family AIG1 PF04548.16 KXS17794.1 - 0.006 15.9 0.3 0.021 14.2 0.1 1.9 2 0 0 2 2 2 1 AIG1 family cobW PF02492.19 KXS17794.1 - 0.021 14.4 0.2 0.13 11.8 0.0 2.2 2 1 1 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 KXS17794.1 - 0.49 9.3 4.5 0.23 10.4 0.1 2.4 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RRM_1 PF00076.22 KXS17795.1 - 4.5e-18 64.8 0.1 6.3e-18 64.4 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KXS17795.1 - 0.016 15.2 0.0 0.026 14.5 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 KXS17795.1 - 0.07 12.7 0.0 0.096 12.3 0.0 1.1 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RPN7 PF10602.9 KXS17797.1 - 4.3e-54 182.8 0.0 6.9e-54 182.2 0.0 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 KXS17797.1 - 7.1e-15 55.4 0.4 2.7e-14 53.6 0.1 2.1 2 0 0 2 2 2 1 PCI domain TPR_1 PF00515.28 KXS17797.1 - 0.00063 19.5 0.3 0.062 13.1 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 KXS17797.1 - 0.0059 16.6 0.7 0.29 11.4 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat Pkinase PF00069.25 KXS17798.1 - 1.3e-61 208.3 0.0 3.4e-56 190.5 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXS17798.1 - 8.4e-30 103.9 0.0 7.1e-29 100.9 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KXS17798.1 - 1.2e-05 25.3 0.8 0.0013 18.7 0.2 2.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KXS17798.1 - 4.7e-05 22.8 0.0 9.5e-05 21.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KXS17798.1 - 0.00021 20.3 0.2 0.00035 19.6 0.2 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KXS17798.1 - 0.0026 17.2 0.0 0.0053 16.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 KXS17798.1 - 0.024 13.7 0.1 0.038 13.0 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.22 KXS17798.1 - 0.2 11.3 0.0 0.33 10.5 0.0 1.3 1 0 0 1 1 1 0 RIO1 family MutL_C PF08676.11 KXS17799.1 - 5.7e-22 78.1 0.0 2.1e-21 76.2 0.0 1.9 1 1 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 KXS17799.1 - 7.6e-15 54.6 0.0 2e-14 53.3 0.0 1.7 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 KXS17799.1 - 1.5e-12 47.5 0.0 4.3e-12 46.0 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KXS17799.1 - 1.6e-08 35.0 0.0 4.1e-08 33.7 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TFIIF_alpha PF05793.12 KXS17799.1 - 5.4 5.5 11.8 8.7 4.8 11.8 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SPT6_acidic PF14632.6 KXS17799.1 - 7.2 7.3 15.7 2.7 8.6 12.4 1.9 2 0 0 2 2 2 0 Acidic N-terminal SPT6 PPR_1 PF12854.7 KXS17800.1 - 4.1e-06 26.4 1.0 0.0031 17.2 0.0 3.8 4 0 0 4 4 4 2 PPR repeat PPR PF01535.20 KXS17800.1 - 6.7e-06 26.0 0.2 1.9 8.9 0.0 4.9 5 0 0 5 5 5 2 PPR repeat TPR_14 PF13428.6 KXS17800.1 - 0.00039 21.0 3.1 3.7 8.6 0.5 5.5 5 1 0 5 5 5 1 Tetratricopeptide repeat PPR_2 PF13041.6 KXS17800.1 - 0.00053 20.1 0.0 13 6.0 0.0 5.0 5 0 0 5 5 5 1 PPR repeat family Glyco_hydro_15 PF00723.21 KXS17801.1 - 6.4e-47 160.4 1.1 8.6e-47 159.9 1.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_21 PF03370.13 KXS17801.1 - 3.4e-07 30.4 4.3 9.4e-07 29.0 4.3 1.8 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CAP_N PF01213.19 KXS17801.1 - 0.0079 15.7 1.3 0.013 15.0 1.3 1.3 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal PL48 PF15903.5 KXS17801.1 - 0.051 12.5 0.0 0.084 11.8 0.0 1.2 1 0 0 1 1 1 0 Filopodia upregulated, FAM65 CBM53 PF16760.5 KXS17801.1 - 0.11 13.1 4.7 0.31 11.7 4.7 1.8 1 0 0 1 1 1 0 Starch/carbohydrate-binding module (family 53) AA_permease_2 PF13520.6 KXS17804.1 - 5.8e-45 153.9 55.1 7.1e-45 153.6 55.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXS17804.1 - 3.4e-15 55.6 50.8 5.4e-15 55.0 50.8 1.2 1 0 0 1 1 1 1 Amino acid permease Phage_holin_3_6 PF07332.11 KXS17804.1 - 0.015 15.4 0.8 0.015 15.4 0.8 5.0 3 2 2 5 5 5 0 Putative Actinobacterial Holin-X, holin superfamily III SNF2_N PF00176.23 KXS17805.1 - 7.9e-67 225.4 0.5 7.9e-67 225.4 0.5 1.9 2 0 0 2 2 2 1 SNF2 family N-terminal domain DBINO PF13892.6 KXS17805.1 - 3e-32 111.8 8.3 3e-32 111.8 8.3 2.5 2 0 0 2 2 2 1 DNA-binding domain Helicase_C PF00271.31 KXS17805.1 - 3e-17 63.0 0.0 6.6e-17 61.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXS17805.1 - 8.7e-08 32.4 0.0 2.8e-07 30.7 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CBP_BcsQ PF06564.12 KXS17805.1 - 0.13 11.7 0.2 0.31 10.5 0.2 1.6 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsQ Gln-synt_C PF00120.24 KXS17806.1 - 2.8e-78 263.3 0.0 3.7e-78 262.9 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain MFS_1 PF07690.16 KXS17808.1 - 1e-38 133.2 29.2 3.5e-38 131.4 28.9 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Methyltransf_25 PF13649.6 KXS17809.1 - 0.0064 17.2 0.0 0.016 15.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KXS17809.1 - 0.022 14.5 0.0 0.53 10.0 0.0 2.3 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_11 PF08241.12 KXS17809.1 - 0.026 15.2 0.0 0.069 13.8 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 KXS17809.1 - 0.078 13.7 0.0 0.19 12.5 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Hydrolase_like PF13242.6 KXS17810.1 - 2.8e-15 56.1 0.2 7.8e-15 54.7 0.0 1.8 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 KXS17810.1 - 5e-15 55.5 0.0 8e-15 54.8 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KXS17810.1 - 2.4e-05 24.5 0.0 0.0003 20.9 0.0 2.0 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KXS17810.1 - 7.7e-05 23.1 0.1 0.0044 17.3 0.1 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.14 KXS17810.1 - 0.2 11.2 0.0 0.3 10.6 0.0 1.2 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) Sel1 PF08238.12 KXS17813.1 - 1.4e-113 368.8 95.1 4.6e-09 36.7 0.3 14.2 14 0 0 14 14 14 14 Sel1 repeat Pkinase_Tyr PF07714.17 KXS17813.1 - 6.3e-10 38.8 0.0 9.3e-10 38.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXS17813.1 - 0.0001 21.8 0.0 0.00015 21.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.25 KXS17814.1 - 3.1e-18 66.1 0.0 3.4e-18 66.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS17814.1 - 2.7e-11 43.3 0.0 3e-11 43.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KXS17814.1 - 0.0078 15.6 0.0 0.0085 15.5 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KXS17814.1 - 0.016 14.6 0.0 0.016 14.6 0.0 1.1 1 0 0 1 1 1 0 Kinase-like DAPDH_C PF16654.5 KXS17814.1 - 0.09 12.6 0.0 0.11 12.3 0.0 1.1 1 0 0 1 1 1 0 Diaminopimelic acid dehydrogenase C-terminal domain Pkinase_Tyr PF07714.17 KXS17815.1 - 0.052 12.8 0.0 0.062 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase ABC1 PF03109.16 KXS17815.1 - 0.063 13.4 0.0 0.082 13.1 0.0 1.2 1 0 0 1 1 1 0 ABC1 family Tho2 PF11262.8 KXS17816.1 - 2e-64 217.7 3.2 7.7e-63 212.5 1.0 2.3 2 0 0 2 2 2 2 Transcription factor/nuclear export subunit protein 2 THOC2_N PF16134.5 KXS17816.1 - 3.5e-56 191.1 0.0 9.2e-56 189.7 0.0 1.6 1 1 0 1 1 1 1 THO complex subunit 2 N-terminus Thoc2 PF11732.8 KXS17816.1 - 2.7e-17 62.6 0.0 5e-17 61.7 0.0 1.5 1 0 0 1 1 1 1 Transcription- and export-related complex subunit MID_MedPIWI PF18296.1 KXS17816.1 - 0.31 10.8 1.0 0.99 9.1 1.0 1.8 1 0 0 1 1 1 0 MID domain of medPIWI EPSP_synthase PF00275.20 KXS17817.1 - 0.15 10.7 0.3 0.17 10.6 0.3 1.0 1 0 0 1 1 1 0 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) F-box PF00646.33 KXS17820.1 - 0.061 13.2 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 F-box domain Vps55 PF04133.14 KXS17823.1 - 3.5e-43 146.3 6.7 4.3e-43 146.0 6.7 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 Herpes_LMP1 PF05297.11 KXS17823.1 - 0.008 15.4 1.0 0.008 15.4 1.0 1.5 2 0 0 2 2 2 1 Herpesvirus latent membrane protein 1 (LMP1) Pkinase PF00069.25 KXS17825.1 - 1.3e-67 228.0 0.0 1.6e-67 227.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS17825.1 - 1.7e-34 119.3 0.0 6e-34 117.5 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXS17825.1 - 4.6e-07 29.4 0.0 1.1e-06 28.2 0.0 1.7 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KXS17825.1 - 2e-05 24.3 0.0 3.3e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 KXS17825.1 - 0.00019 21.4 0.8 0.001 19.0 0.3 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KXS17825.1 - 0.0011 18.3 0.4 0.002 17.5 0.4 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KXS17825.1 - 0.042 12.6 0.0 0.063 12.0 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase YrbL-PhoP_reg PF10707.9 KXS17825.1 - 0.045 13.3 0.0 0.07 12.6 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL PUL PF08324.11 KXS17826.1 - 6.9e-45 153.4 0.0 1.1e-44 152.8 0.0 1.2 1 0 0 1 1 1 1 PUL domain PFU PF09070.11 KXS17826.1 - 6.2e-40 136.0 0.1 1.3e-39 135.0 0.1 1.6 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.32 KXS17826.1 - 2.7e-34 116.6 19.2 0.00011 22.9 0.0 8.1 8 0 0 8 8 8 7 WD domain, G-beta repeat MFS_1 PF07690.16 KXS17827.1 - 1.2e-33 116.5 64.1 2.8e-29 102.2 33.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF262 PF03235.14 KXS17830.1 - 0.011 15.9 0.0 0.05 13.8 0.0 1.9 1 1 0 2 2 2 0 Protein of unknown function DUF262 Rax2 PF12768.7 KXS17831.1 - 0.0099 15.4 0.4 0.016 14.7 0.4 1.3 1 0 0 1 1 1 1 Cortical protein marker for cell polarity HALZ PF02183.18 KXS17834.1 - 0.0003 20.9 0.3 0.0062 16.7 0.0 2.2 1 1 1 2 2 2 1 Homeobox associated leucine zipper Shugoshin_N PF07558.11 KXS17834.1 - 0.00064 19.5 1.9 0.04 13.8 1.8 2.2 1 1 1 2 2 2 2 Shugoshin N-terminal coiled-coil region SH3_9 PF14604.6 KXS17834.1 - 0.0033 17.2 0.0 0.0081 16.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain bZIP_2 PF07716.15 KXS17834.1 - 0.0058 16.7 2.8 0.14 12.3 1.3 2.5 1 1 0 2 2 2 1 Basic region leucine zipper KASH_CCD PF14662.6 KXS17834.1 - 0.011 15.5 0.1 0.015 15.1 0.1 1.1 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH SH3_1 PF00018.28 KXS17834.1 - 0.015 14.9 0.5 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 SH3 domain Rootletin PF15035.6 KXS17834.1 - 0.016 15.2 0.7 0.022 14.8 0.7 1.1 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion SH3_2 PF07653.17 KXS17834.1 - 0.027 14.1 0.0 0.072 12.8 0.0 1.7 1 0 0 1 1 1 0 Variant SH3 domain TSC22 PF01166.18 KXS17834.1 - 0.038 14.3 0.5 0.58 10.5 0.3 2.2 1 1 2 3 3 3 0 TSC-22/dip/bun family TMF_DNA_bd PF12329.8 KXS17834.1 - 0.053 13.5 0.0 0.08 12.9 0.0 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Csm1_N PF18504.1 KXS17834.1 - 0.086 13.2 0.1 0.15 12.4 0.1 1.4 1 0 0 1 1 1 0 Csm1 N-terminal domain bZIP_1 PF00170.21 KXS17834.1 - 0.097 12.8 0.3 0.27 11.4 0.2 1.5 1 1 0 1 1 1 0 bZIP transcription factor ZapB PF06005.12 KXS17834.1 - 0.098 13.1 1.3 0.2 12.1 1.0 1.5 1 1 0 1 1 1 0 Cell division protein ZapB Cep57_CLD_2 PF14197.6 KXS17834.1 - 0.14 12.3 1.3 0.22 11.6 1.3 1.3 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 Tropomyosin_1 PF12718.7 KXS17834.1 - 0.14 12.3 0.0 0.19 11.9 0.0 1.1 1 0 0 1 1 1 0 Tropomyosin like Filament PF00038.21 KXS17834.1 - 0.17 11.5 0.4 0.21 11.1 0.4 1.1 1 0 0 1 1 1 0 Intermediate filament protein DivIC PF04977.15 KXS17834.1 - 0.17 11.7 0.9 0.51 10.1 0.9 1.8 1 1 0 1 1 1 0 Septum formation initiator CENP-H PF05837.12 KXS17834.1 - 0.2 12.1 0.4 0.31 11.5 0.4 1.2 1 0 0 1 1 1 0 Centromere protein H (CENP-H) SH3_9 PF14604.6 KXS17837.1 - 1.3e-08 34.6 0.0 2.3e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXS17837.1 - 1e-07 31.4 0.0 2e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 SH3 domain HALZ PF02183.18 KXS17837.1 - 8.7e-05 22.7 1.3 0.62 10.3 0.0 2.9 3 0 0 3 3 3 2 Homeobox associated leucine zipper YabA PF06156.13 KXS17837.1 - 0.00016 22.3 3.1 0.011 16.3 0.1 2.4 1 1 1 2 2 2 1 Initiation control protein YabA NRBF2 PF08961.10 KXS17837.1 - 0.00085 19.0 6.0 0.082 12.5 1.1 2.2 1 1 1 2 2 2 2 Nuclear receptor-binding factor 2, autophagy regulator Rootletin PF15035.6 KXS17837.1 - 0.0019 18.2 0.8 0.003 17.6 0.8 1.2 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion Ank_3 PF13606.6 KXS17837.1 - 0.0023 18.3 0.1 0.17 12.5 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeat SH3_2 PF07653.17 KXS17837.1 - 0.0035 17.0 0.0 0.0078 15.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Ank_2 PF12796.7 KXS17837.1 - 0.0043 17.6 0.0 0.85 10.3 0.1 3.2 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXS17837.1 - 0.0061 17.1 0.0 3.9 8.2 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeats (many copies) ATG16 PF08614.11 KXS17837.1 - 0.01 16.1 5.3 0.018 15.3 5.3 1.4 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) KASH_CCD PF14662.6 KXS17837.1 - 0.013 15.4 6.2 0.025 14.4 6.2 1.4 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH FPP PF05911.11 KXS17837.1 - 0.014 13.6 0.6 0.019 13.2 0.6 1.0 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil DivIC PF04977.15 KXS17837.1 - 0.021 14.6 6.6 0.72 9.7 0.9 3.3 2 1 1 3 3 3 0 Septum formation initiator CENP-F_leu_zip PF10473.9 KXS17837.1 - 0.027 14.5 3.1 0.045 13.8 3.1 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Cnn_1N PF07989.11 KXS17837.1 - 0.027 14.6 2.5 0.086 13.0 0.5 2.3 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 bZIP_1 PF00170.21 KXS17837.1 - 0.029 14.5 0.3 4.2 7.6 0.0 2.5 1 1 1 2 2 2 0 bZIP transcription factor JIP_LZII PF16471.5 KXS17837.1 - 0.036 14.2 1.9 0.088 13.0 1.9 1.7 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II ZapB PF06005.12 KXS17837.1 - 0.052 14.0 7.1 0.43 11.1 0.1 2.9 1 1 2 3 3 3 0 Cell division protein ZapB TSC22 PF01166.18 KXS17837.1 - 0.068 13.5 3.6 4.7 7.6 0.1 3.1 2 1 1 3 3 3 0 TSC-22/dip/bun family GTP-bdg_N PF13167.6 KXS17837.1 - 0.072 13.8 0.9 0.16 12.7 0.9 1.5 1 0 0 1 1 1 0 GTP-binding GTPase N-terminal Shugoshin_N PF07558.11 KXS17837.1 - 0.087 12.7 0.4 35 4.4 0.1 3.3 3 1 0 3 3 3 0 Shugoshin N-terminal coiled-coil region Flu_M1_C PF08289.11 KXS17837.1 - 0.093 13.0 0.5 0.56 10.5 0.6 2.1 2 0 0 2 2 2 0 Influenza Matrix protein (M1) C-terminal domain DUF2353 PF09789.9 KXS17837.1 - 0.13 11.6 2.8 0.19 11.0 2.8 1.2 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) TMF_DNA_bd PF12329.8 KXS17837.1 - 0.21 11.6 3.9 0.5 10.4 0.4 2.3 1 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding TPR_MLP1_2 PF07926.12 KXS17837.1 - 0.26 11.4 10.6 0.41 10.7 10.6 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF4472 PF14739.6 KXS17837.1 - 0.3 11.8 6.0 1.1 10.1 4.7 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) CENP-H PF05837.12 KXS17837.1 - 0.44 11.0 10.7 1.4 9.4 0.1 3.0 1 1 2 3 3 3 0 Centromere protein H (CENP-H) SlyX PF04102.12 KXS17837.1 - 0.8 10.4 5.6 13 6.5 2.4 2.8 1 1 1 2 2 2 0 SlyX Ax_dynein_light PF10211.9 KXS17837.1 - 0.91 9.4 4.6 1.3 8.9 0.3 2.1 1 1 1 2 2 2 0 Axonemal dynein light chain Cep57_CLD_2 PF14197.6 KXS17837.1 - 2.2 8.5 7.9 2.2 8.4 0.6 2.6 1 1 0 2 2 2 0 Centrosome localisation domain of PPC89 Csm1_N PF18504.1 KXS17837.1 - 3.5 8.0 5.5 16 5.9 0.2 3.0 2 1 1 3 3 3 0 Csm1 N-terminal domain PRKG1_interact PF15898.5 KXS17837.1 - 4.3 8.3 7.7 5.2 8.0 3.4 2.3 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain DUF2968 PF11180.8 KXS17837.1 - 4.5 6.9 11.9 8.1 6.0 11.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2968) TSC22 PF01166.18 KXS17838.1 - 3.3e-06 27.3 1.3 0.087 13.2 0.6 2.8 1 1 1 3 3 3 2 TSC-22/dip/bun family bZIP_1 PF00170.21 KXS17838.1 - 2.3e-05 24.4 0.6 0.0032 17.5 0.3 2.4 1 1 1 2 2 2 2 bZIP transcription factor ZapB PF06005.12 KXS17838.1 - 5.9e-05 23.4 1.6 0.016 15.6 0.2 2.3 1 1 1 2 2 2 2 Cell division protein ZapB WD40_alt PF14077.6 KXS17838.1 - 0.00012 21.9 0.7 0.63 9.9 0.0 3.1 1 1 2 3 3 3 1 Alternative WD40 repeat motif KASH_CCD PF14662.6 KXS17838.1 - 0.00014 21.7 0.5 0.00021 21.2 0.5 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH bZIP_2 PF07716.15 KXS17838.1 - 0.00017 21.6 0.6 0.024 14.7 0.3 2.4 2 1 0 2 2 2 1 Basic region leucine zipper YabA PF06156.13 KXS17838.1 - 0.00022 21.8 0.7 0.058 14.0 0.5 2.2 1 1 1 2 2 2 2 Initiation control protein YabA GIT_CC PF16559.5 KXS17838.1 - 0.00028 20.7 4.2 0.0035 17.2 3.1 2.3 2 0 0 2 2 2 1 GIT coiled-coil Rho guanine nucleotide exchange factor DivIC PF04977.15 KXS17838.1 - 0.00042 20.0 0.8 0.2 11.5 0.8 2.2 1 1 1 2 2 2 1 Septum formation initiator ATG16 PF08614.11 KXS17838.1 - 0.00068 19.9 4.4 0.00085 19.6 4.4 1.0 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Tropomyosin_1 PF12718.7 KXS17838.1 - 0.001 19.3 0.6 0.0015 18.7 0.6 1.2 1 0 0 1 1 1 1 Tropomyosin like Cep57_CLD_2 PF14197.6 KXS17838.1 - 0.002 18.1 4.0 0.15 12.1 2.5 2.2 1 1 1 2 2 2 1 Centrosome localisation domain of PPC89 HALZ PF02183.18 KXS17838.1 - 0.0021 18.2 1.6 0.31 11.3 0.4 3.0 1 1 2 3 3 3 2 Homeobox associated leucine zipper Rootletin PF15035.6 KXS17838.1 - 0.0024 17.9 6.6 0.044 13.8 3.3 2.1 1 1 1 2 2 2 1 Ciliary rootlet component, centrosome cohesion UPF0242 PF06785.11 KXS17838.1 - 0.0031 17.6 0.7 0.0038 17.4 0.7 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus CASP_C PF08172.12 KXS17838.1 - 0.0033 16.8 1.2 0.0033 16.8 1.2 1.7 2 1 0 2 2 2 1 CASP C terminal Uso1_p115_C PF04871.13 KXS17838.1 - 0.0035 17.7 0.9 0.0059 17.0 0.9 1.3 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, C terminal region DUF2353 PF09789.9 KXS17838.1 - 0.0036 16.7 3.5 0.0062 15.9 3.5 1.4 1 1 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) TMF_DNA_bd PF12329.8 KXS17838.1 - 0.0087 16.0 2.9 0.048 13.7 3.1 1.8 1 1 1 2 2 2 1 TATA element modulatory factor 1 DNA binding CENP-H PF05837.12 KXS17838.1 - 0.0089 16.4 1.9 0.02 15.3 1.9 1.6 1 1 0 1 1 1 1 Centromere protein H (CENP-H) ADIP PF11559.8 KXS17838.1 - 0.011 15.8 2.3 0.014 15.4 2.3 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding MAD PF05557.13 KXS17838.1 - 0.012 14.0 0.6 0.015 13.7 0.6 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein DUF2968 PF11180.8 KXS17838.1 - 0.013 15.2 1.6 0.019 14.6 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) Shugoshin_N PF07558.11 KXS17838.1 - 0.015 15.2 9.7 0.32 10.9 1.9 3.2 1 1 2 3 3 3 0 Shugoshin N-terminal coiled-coil region JIP_LZII PF16471.5 KXS17838.1 - 0.016 15.4 4.2 1.7 8.9 0.5 2.9 1 1 3 4 4 4 0 JNK-interacting protein leucine zipper II HMMR_C PF15908.5 KXS17838.1 - 0.018 15.3 0.8 2.9 8.2 0.1 2.3 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor C-terminal Spc7 PF08317.11 KXS17838.1 - 0.019 13.9 0.6 0.023 13.6 0.6 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein FlaC_arch PF05377.11 KXS17838.1 - 0.019 15.3 0.5 0.85 10.1 0.2 2.2 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) DUF1615 PF07759.12 KXS17838.1 - 0.021 14.1 0.8 0.024 13.9 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1615) CENP-F_leu_zip PF10473.9 KXS17838.1 - 0.023 14.7 1.6 0.039 14.0 1.6 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 K-box PF01486.17 KXS17838.1 - 0.03 14.5 1.4 0.61 10.3 0.3 2.4 1 1 0 1 1 1 0 K-box region DUF3450 PF11932.8 KXS17838.1 - 0.031 13.6 1.1 0.04 13.2 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) GAS PF13851.6 KXS17838.1 - 0.04 13.3 0.2 0.054 12.8 0.2 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding KLRAQ PF10205.9 KXS17838.1 - 0.041 14.1 1.5 0.11 12.7 1.5 1.7 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein DUF5082 PF16888.5 KXS17838.1 - 0.045 14.0 1.5 0.072 13.4 1.3 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) Lectin_N PF03954.14 KXS17838.1 - 0.047 13.4 4.2 0.068 12.9 4.2 1.4 1 1 0 1 1 1 0 Hepatic lectin, N-terminal domain TMF_TATA_bd PF12325.8 KXS17838.1 - 0.051 13.8 3.2 0.37 11.0 3.1 1.9 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DUF4201 PF13870.6 KXS17838.1 - 0.054 13.2 0.9 0.12 12.2 0.9 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) APG6_N PF17675.1 KXS17838.1 - 0.066 13.7 2.1 0.1 13.1 2.1 1.4 1 1 0 1 1 1 0 Apg6 coiled-coil region RasGAP_C PF03836.15 KXS17838.1 - 0.073 13.2 0.4 0.1 12.7 0.4 1.1 1 0 0 1 1 1 0 RasGAP C-terminus Macoilin PF09726.9 KXS17838.1 - 0.074 11.6 1.9 0.096 11.2 1.9 1.2 1 0 0 1 1 1 0 Macoilin family NRBF2 PF08961.10 KXS17838.1 - 0.085 12.5 1.6 5.4 6.6 0.6 2.1 1 1 1 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator HOOK PF05622.12 KXS17838.1 - 0.14 10.3 1.9 0.89 7.6 2.1 1.6 1 1 0 1 1 1 0 HOOK protein Fungal_TACC PF12709.7 KXS17838.1 - 0.17 12.4 0.2 0.67 10.4 0.1 1.9 1 1 1 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins Cnn_1N PF07989.11 KXS17838.1 - 0.18 12.0 1.0 1 9.6 1.0 2.1 1 1 0 1 1 1 0 Centrosomin N-terminal motif 1 TPR_MLP1_2 PF07926.12 KXS17838.1 - 0.25 11.4 3.8 0.48 10.5 3.0 1.6 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein NYD-SP28_assoc PF14775.6 KXS17838.1 - 0.25 11.5 6.0 15 5.8 0.4 3.3 1 1 2 3 3 3 0 Sperm tail C-terminal domain Csm1_N PF18504.1 KXS17838.1 - 0.26 11.7 2.4 0.77 10.1 1.7 2.0 1 1 1 2 2 2 0 Csm1 N-terminal domain Jnk-SapK_ap_N PF09744.9 KXS17838.1 - 0.54 10.5 4.1 0.88 9.8 4.1 1.4 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 TMF_DNA_bd PF12329.8 KXS17839.1 - 0.12 12.4 0.5 0.18 11.8 0.5 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Ank_3 PF13606.6 KXS17840.1 - 9.9e-05 22.5 0.0 0.018 15.5 0.0 3.5 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.7 KXS17840.1 - 0.0014 19.2 0.1 0.36 11.4 0.0 3.2 2 2 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXS17840.1 - 0.021 15.4 0.0 0.56 10.9 0.0 2.6 2 1 0 2 2 2 0 Ankyrin repeats (many copies) Ank PF00023.30 KXS17840.1 - 0.084 13.4 0.1 5 7.7 0.1 2.9 2 0 0 2 2 2 0 Ankyrin repeat Ank_4 PF13637.6 KXS17841.1 - 0.00034 21.1 0.0 0.19 12.4 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXS17841.1 - 0.00084 19.6 0.1 0.063 13.9 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.7 KXS17841.1 - 0.041 14.5 0.0 3.5 8.3 0.0 2.3 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXS17841.1 - 0.1 13.0 0.1 16 6.0 0.0 2.8 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXS17844.1 - 0.0011 19.5 0.0 0.0016 19.0 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXS17844.1 - 0.0058 17.2 0.3 0.29 11.8 0.1 2.4 1 1 1 2 2 2 1 Ankyrin repeats (many copies) RNA12 PF10443.9 KXS17844.1 - 0.041 12.6 0.0 0.041 12.6 0.0 1.0 1 0 0 1 1 1 0 RNA12 protein Dioxygenase_C PF00775.21 KXS17845.1 - 5.9e-05 22.6 0.1 0.0001 21.8 0.1 1.4 1 0 0 1 1 1 1 Dioxygenase Macscav_rec PF03523.13 KXS17856.1 - 0.044 13.7 1.0 6 6.8 0.1 2.2 2 0 0 2 2 2 0 Macrophage scavenger receptor CDC45 PF02724.14 KXS17857.1 - 0.055 11.8 7.6 0.047 12.0 7.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 KXS17857.1 - 2.4 6.3 18.9 2.7 6.1 18.9 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 KXS17857.1 - 4.2 6.6 14.4 5.2 6.3 14.4 1.2 1 0 0 1 1 1 0 BUD22 RRN3 PF05327.11 KXS17857.1 - 9.3 4.7 6.5 8.2 4.8 6.5 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 FAD_binding_3 PF01494.19 KXS17858.1 - 2e-67 227.9 0.0 1.9e-66 224.7 0.0 2.3 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 KXS17858.1 - 7e-31 107.5 0.0 1.2e-30 106.7 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain HI0933_like PF03486.14 KXS17858.1 - 0.0014 17.5 0.0 0.0021 16.9 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.14 KXS17858.1 - 0.0021 17.3 0.4 0.0071 15.6 0.1 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXS17858.1 - 0.0085 16.3 0.0 0.026 14.8 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KXS17858.1 - 0.013 14.6 0.0 0.021 13.9 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.24 KXS17858.1 - 0.016 14.8 0.0 0.045 13.3 0.0 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.22 KXS17858.1 - 0.046 12.8 0.0 0.094 11.8 0.0 1.5 1 0 0 1 1 1 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 KXS17858.1 - 0.048 12.7 0.0 0.074 12.1 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein SE PF08491.10 KXS17858.1 - 0.068 12.2 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase Thi4 PF01946.17 KXS17858.1 - 0.17 11.1 0.0 0.28 10.4 0.0 1.2 1 0 0 1 1 1 0 Thi4 family RED_N PF07808.13 KXS17859.1 - 6.2e-28 98.0 2.2 6.2e-28 98.0 2.2 4.4 3 1 1 4 4 4 1 RED-like protein N-terminal region TBCA PF02970.16 KXS17860.1 - 8.1e-30 103.0 4.4 9.4e-30 102.8 4.4 1.0 1 0 0 1 1 1 1 Tubulin binding cofactor A P4Ha_N PF08336.11 KXS17860.1 - 0.016 15.2 0.3 0.023 14.7 0.3 1.2 1 0 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region TelA PF05816.11 KXS17860.1 - 0.029 13.4 0.9 0.036 13.1 0.9 1.0 1 0 0 1 1 1 0 Toxic anion resistance protein (TelA) STAT_alpha PF01017.20 KXS17860.1 - 0.029 14.3 1.1 0.033 14.1 1.1 1.0 1 0 0 1 1 1 0 STAT protein, all-alpha domain DUF1699 PF08004.11 KXS17860.1 - 0.092 12.4 1.6 0.11 12.2 1.5 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1699) DUF948 PF06103.11 KXS17860.1 - 0.1 12.9 0.2 8.2 6.8 0.0 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) FapA PF03961.13 KXS17860.1 - 0.11 11.0 2.4 0.13 10.8 2.4 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A Val_tRNA-synt_C PF10458.9 KXS17860.1 - 0.19 12.1 0.2 0.19 12.1 0.2 2.6 1 1 2 3 3 3 0 Valyl tRNA synthetase tRNA binding arm Vps51 PF08700.11 KXS17861.1 - 2.7e-21 75.4 0.2 8e-21 73.9 0.2 1.9 1 0 0 1 1 1 1 Vps51/Vps67 Sec5 PF15469.6 KXS17861.1 - 3.6e-16 59.6 0.0 6.5e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 Exocyst complex component Sec5 Dor1 PF04124.12 KXS17861.1 - 3.5e-08 32.5 0.3 7e-08 31.5 0.3 1.4 1 0 0 1 1 1 1 Dor1-like family Vps54_N PF10475.9 KXS17861.1 - 4.1e-08 32.9 0.1 7.7e-08 32.0 0.1 1.4 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex COG5 PF10392.9 KXS17861.1 - 7.9e-08 32.6 0.8 1.9e-07 31.3 0.0 2.1 2 0 0 2 2 1 1 Golgi transport complex subunit 5 COG2 PF06148.11 KXS17861.1 - 2.4e-06 27.7 2.7 1.6e-05 25.0 0.3 3.0 3 0 0 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 Sec8_exocyst PF04048.14 KXS17861.1 - 4.9e-05 23.3 0.2 0.00018 21.4 0.1 2.1 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain Zw10 PF06248.13 KXS17861.1 - 0.00048 18.8 0.4 0.0079 14.8 0.4 2.2 2 0 0 2 2 2 1 Centromere/kinetochore Zw10 Vps53_N PF04100.12 KXS17861.1 - 0.00071 18.7 0.1 0.0012 17.9 0.1 1.3 1 0 0 1 1 1 1 Vps53-like, N-terminal FlaC_arch PF05377.11 KXS17861.1 - 0.037 14.4 0.5 0.13 12.7 0.5 1.9 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) HrpB7 PF09486.10 KXS17861.1 - 1.5 9.2 7.7 2.9 8.3 0.0 3.2 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB7) Macoilin PF09726.9 KXS17861.1 - 2.2 6.7 5.9 4.9 5.6 5.9 1.6 1 0 0 1 1 1 0 Macoilin family Glyco_hydro_26 PF02156.15 KXS17862.1 - 6.9e-06 25.7 0.4 0.00078 19.0 0.0 2.2 2 0 0 2 2 2 2 Glycosyl hydrolase family 26 EF-hand_5 PF13202.6 KXS17862.1 - 0.069 12.7 0.5 0.41 10.2 0.6 2.2 1 1 1 2 2 2 0 EF hand His_Phos_1 PF00300.22 KXS17863.1 - 4.2e-28 98.4 0.7 6.2e-28 97.8 0.7 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) LRR_4 PF12799.7 KXS17864.1 - 1.4e-11 44.4 4.9 0.00049 20.4 0.4 4.2 3 1 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXS17864.1 - 9.3e-10 38.1 6.4 1.3e-07 31.2 2.9 4.0 3 1 1 4 4 4 2 Leucine rich repeat LRR_6 PF13516.6 KXS17864.1 - 7.3e-06 25.6 4.6 1 9.6 0.0 4.7 4 0 0 4 4 4 2 Leucine Rich repeat LRR_9 PF14580.6 KXS17864.1 - 4.6e-05 23.0 0.1 0.00017 21.2 0.1 1.8 1 1 0 1 1 1 1 Leucine-rich repeat HAUS-augmin3 PF14932.6 KXS17864.1 - 0.47 10.0 4.1 0.87 9.1 4.1 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 LRR_1 PF00560.33 KXS17864.1 - 0.55 11.0 6.7 16 6.6 1.3 4.5 3 1 0 3 3 3 0 Leucine Rich Repeat Nup54 PF13874.6 KXS17864.1 - 3.1 7.9 7.7 9.1 6.4 7.7 1.8 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 CHZ PF09649.10 KXS17864.1 - 10 5.7 7.6 0.36 10.4 0.2 2.5 2 0 0 2 2 2 0 Histone chaperone domain CHZ PARG_cat PF05028.14 KXS17865.1 - 5.7e-16 58.7 0.0 2.7e-11 43.4 0.0 2.0 2 0 0 2 2 2 2 Poly (ADP-ribose) glycohydrolase (PARG) Pkinase PF00069.25 KXS17866.1 - 6e-65 219.2 0.0 8.9e-65 218.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS17866.1 - 3e-37 128.3 0.0 4.6e-37 127.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXS17866.1 - 0.0084 15.5 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 KXS17866.1 - 0.048 12.7 0.0 0.089 11.8 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 DUF5128 PF17170.4 KXS17866.1 - 0.15 11.2 0.0 0.23 10.6 0.0 1.2 1 0 0 1 1 1 0 6-bladed beta-propeller Sec3_C PF09763.9 KXS17867.1 - 1.4e-137 460.0 0.0 1.1e-136 457.1 0.0 1.9 1 1 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.6 KXS17867.1 - 1e-12 48.0 0.1 2.6e-12 46.7 0.0 1.8 2 0 0 2 2 2 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Vps52 PF04129.12 KXS17867.1 - 0.014 14.2 0.3 0.061 12.1 0.3 2.0 1 1 0 1 1 1 0 Vps52 / Sac2 family Csm2_III-A PF03750.13 KXS17867.1 - 2.8 8.8 7.1 0.33 11.8 0.4 2.8 3 0 0 3 3 3 0 Csm2 Type III-A Abhydrolase_6 PF12697.7 KXS17868.1 - 3.6e-12 47.4 0.7 4.5e-12 47.1 0.7 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXS17868.1 - 0.0091 15.3 0.0 0.014 14.6 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 C1_1 PF00130.22 KXS17869.1 - 0.00035 20.4 5.8 0.00035 20.4 5.8 1.9 1 1 1 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_2 PF13639.6 KXS17869.1 - 0.0016 18.8 13.6 0.0016 18.8 13.6 1.9 2 0 0 2 2 2 1 Ring finger domain SWIM PF04434.17 KXS17869.1 - 0.0018 17.9 0.6 0.0039 16.8 0.6 1.6 1 0 0 1 1 1 1 SWIM zinc finger FANCL_C PF11793.8 KXS17869.1 - 0.083 13.1 8.5 0.18 12.0 8.5 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain DZR PF12773.7 KXS17869.1 - 0.71 9.9 10.4 3 7.9 3.6 2.4 1 1 1 2 2 2 0 Double zinc ribbon zf-RING_UBOX PF13445.6 KXS17869.1 - 2 8.5 10.2 4.6 7.4 10.2 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KXS17869.1 - 3.4 7.6 11.6 97 2.9 11.6 2.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) AA_permease_2 PF13520.6 KXS17870.1 - 4.6e-56 190.5 22.4 5.6e-56 190.2 22.4 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXS17870.1 - 8.2e-29 100.5 24.0 1.9e-28 99.3 24.0 1.5 1 1 0 1 1 1 1 Amino acid permease Aa_trans PF01490.18 KXS17870.1 - 0.031 13.0 13.7 0.039 12.7 0.1 3.3 3 0 0 3 3 3 0 Transmembrane amino acid transporter protein DUF4213 PF13938.6 KXS17870.1 - 0.15 12.3 0.8 0.36 11.1 0.1 2.0 2 0 0 2 2 2 0 Putative heavy-metal chelation AMP-binding PF00501.28 KXS17871.1 - 2.5e-92 309.7 0.0 3e-92 309.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXS17871.1 - 9e-25 87.5 1.4 1.9e-24 86.4 0.2 2.3 2 1 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 KXS17871.1 - 4.2e-15 55.4 0.4 9.9e-15 54.2 0.4 1.7 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus zf-AN1 PF01428.16 KXS17874.1 - 8.4e-19 67.5 25.4 5.3e-11 42.5 8.3 2.6 3 0 0 3 3 3 2 AN1-like Zinc finger RAP80_UIM PF18282.1 KXS17874.1 - 0.0041 16.9 4.3 0.3 10.9 0.8 2.4 1 1 1 2 2 2 2 RAP80 N-terminal ubiquitin interaction motif UIM PF02809.20 KXS17874.1 - 0.0049 16.7 12.7 0.019 14.8 1.2 2.3 2 0 0 2 2 2 2 Ubiquitin interaction motif zf-C2HC5 PF06221.13 KXS17874.1 - 0.082 12.9 7.9 0.24 11.4 0.3 3.0 3 0 0 3 3 3 0 Putative zinc finger motif, C2HC5-type Transp_Tc5_C PF04236.15 KXS17874.1 - 0.13 12.7 13.9 0.16 12.4 5.8 2.4 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain Proteasome PF00227.26 KXS17875.1 - 5.8e-49 166.2 0.1 7.3e-49 165.8 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.8 KXS17875.1 - 3e-08 32.9 0.1 3e-08 32.9 0.1 1.8 2 0 0 2 2 2 1 Proteasome beta subunits C terminal SLD5_C PF16922.5 KXS17876.1 - 3.3e-12 46.4 0.5 7.5e-12 45.3 0.5 1.6 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus Sld5 PF05916.11 KXS17876.1 - 8.2e-06 26.2 0.2 1.6e-05 25.4 0.2 1.5 1 0 0 1 1 1 1 GINS complex protein Ribosomal_L35p PF01632.19 KXS17877.1 - 1.6e-10 41.3 11.2 1.6e-10 41.3 11.2 1.7 2 0 0 2 2 2 1 Ribosomal protein L35 Fungal_trans PF04082.18 KXS17880.1 - 3e-14 52.7 0.3 7.1e-14 51.5 0.3 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXS17880.1 - 3.1e-06 27.2 11.1 4.9e-06 26.6 11.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HTH_IclR PF09339.10 KXS17880.1 - 0.12 12.2 0.4 11 5.9 0.0 2.5 2 0 0 2 2 2 0 IclR helix-turn-helix domain SE PF08491.10 KXS17881.1 - 1.6e-87 293.1 0.0 9.1e-87 290.6 0.0 1.9 1 1 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.19 KXS17881.1 - 2.6e-10 40.1 0.0 3.3e-08 33.2 0.0 2.3 2 1 0 2 2 2 1 FAD binding domain DAO PF01266.24 KXS17881.1 - 4.7e-08 33.0 0.1 0.001 18.7 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KXS17881.1 - 0.0009 18.4 2.0 0.039 13.0 0.3 2.3 2 0 0 2 2 2 1 FAD binding domain Trp_halogenase PF04820.14 KXS17881.1 - 0.0018 17.2 0.1 0.21 10.4 0.0 2.7 3 0 0 3 3 3 1 Tryptophan halogenase 3HCDH_N PF02737.18 KXS17881.1 - 0.012 15.4 0.0 0.019 14.8 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 KXS17881.1 - 0.022 14.3 0.1 0.036 13.6 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_8 PF13450.6 KXS17881.1 - 0.024 14.9 0.1 0.054 13.7 0.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KXS17881.1 - 0.036 13.4 0.2 0.062 12.6 0.2 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.22 KXS17881.1 - 0.041 13.0 0.5 0.13 11.3 0.5 1.8 1 1 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox PF00070.27 KXS17881.1 - 0.046 14.3 0.7 0.15 12.7 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXS17881.1 - 0.06 12.6 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GDI PF00996.18 KXS17881.1 - 0.062 11.8 0.0 0.09 11.3 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor HI0933_like PF03486.14 KXS17881.1 - 0.079 11.6 0.0 0.11 11.1 0.0 1.1 1 0 0 1 1 1 0 HI0933-like protein ApbA PF02558.16 KXS17881.1 - 0.14 11.8 0.1 0.24 11.0 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Thi4 PF01946.17 KXS17881.1 - 0.18 11.0 0.1 0.33 10.2 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Sacchrp_dh_NADP PF03435.18 KXS17881.1 - 0.19 12.0 0.1 0.32 11.3 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Lycopene_cycl PF05834.12 KXS17881.1 - 0.26 10.3 1.3 3.3 6.7 0.3 2.6 3 0 0 3 3 3 0 Lycopene cyclase protein CoA_binding PF02629.19 KXS17882.1 - 4.1e-26 91.5 3.6 4.4e-26 91.4 0.4 2.5 2 1 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 KXS17882.1 - 4.9e-24 84.9 0.4 1e-23 83.8 0.3 1.6 2 0 0 2 2 2 1 CoA-ligase Succ_CoA_lig PF13607.6 KXS17882.1 - 1.1e-08 34.9 0.0 2e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 KXS17882.1 - 0.00034 21.1 0.1 0.0073 16.8 0.0 2.9 4 0 0 4 4 4 1 CoA binding domain GFO_IDH_MocA PF01408.22 KXS17882.1 - 0.047 14.5 0.1 0.18 12.6 0.1 2.1 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold Peripla_BP_4 PF13407.6 KXS17882.1 - 4 6.9 5.9 4.8 6.7 0.6 3.1 2 2 1 3 3 3 0 Periplasmic binding protein domain SprT-like PF10263.9 KXS17883.1 - 1.2e-29 102.4 0.0 1.7e-29 102.0 0.0 1.2 1 0 0 1 1 1 1 SprT-like family Zn_ribbon_SprT PF17283.2 KXS17883.1 - 4.2e-06 26.6 3.7 8.2e-06 25.6 3.7 1.5 1 0 0 1 1 1 1 SprT-like zinc ribbon domain Tox-MPTase2 PF15638.6 KXS17883.1 - 0.013 15.2 0.0 0.019 14.7 0.0 1.2 1 0 0 1 1 1 0 Metallopeptidase toxin 2 Peptidase_M76 PF09768.9 KXS17883.1 - 0.022 14.5 0.0 0.038 13.8 0.0 1.4 1 0 0 1 1 1 0 Peptidase M76 family MCM PF00493.23 KXS17884.1 - 1.9e-93 311.7 0.1 2.9e-93 311.1 0.1 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KXS17884.1 - 2.8e-34 117.7 0.0 8.2e-34 116.2 0.0 1.8 2 0 0 2 2 2 1 MCM OB domain MCM_lid PF17855.1 KXS17884.1 - 5.4e-24 84.4 1.6 1.1e-23 83.4 1.6 1.5 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KXS17884.1 - 1.6e-12 47.9 0.0 4.4e-12 46.5 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KXS17884.1 - 1.3e-08 34.5 0.3 1.8e-06 27.5 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KXS17884.1 - 0.00072 19.4 0.1 0.0023 17.8 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KXS17884.1 - 0.0082 15.9 0.1 0.031 14.0 0.0 2.0 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_5 PF07728.14 KXS17884.1 - 0.04 13.9 0.1 0.27 11.3 0.0 2.4 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) MAS20 PF02064.15 KXS17885.1 - 9.2e-28 96.9 7.6 3.9e-14 52.9 2.7 3.0 3 0 0 3 3 3 2 MAS20 protein import receptor SET PF00856.28 KXS17885.1 - 1.1e-09 38.9 0.0 7.3e-09 36.2 0.0 2.3 3 1 0 3 3 3 1 SET domain SAF PF08666.12 KXS17885.1 - 0.0087 16.7 0.4 7.5 7.3 0.1 2.7 2 0 0 2 2 2 2 SAF domain UCR_Fe-S_N PF10399.9 KXS17885.1 - 0.016 14.6 2.9 0.031 13.6 2.9 1.5 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal ABA_WDS PF02496.16 KXS17885.1 - 0.42 11.1 7.6 3.3 8.3 0.4 2.5 2 0 0 2 2 2 0 ABA/WDS induced protein TauD PF02668.16 KXS17886.1 - 8.5e-48 163.5 0.3 1.1e-47 163.1 0.3 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Phage_H_T_join PF05521.11 KXS17886.1 - 0.2 12.2 1.1 0.94 10.0 0.0 2.5 2 1 0 2 2 2 0 Phage head-tail joining protein MFS_1 PF07690.16 KXS17887.1 - 2.8e-32 112.0 23.6 3.9e-32 111.6 23.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 KXS17887.1 - 0.00096 18.1 5.2 0.00096 18.1 5.2 2.4 2 1 1 3 3 3 1 MFS_1 like family FAD_binding_3 PF01494.19 KXS17888.1 - 3e-07 30.0 0.0 0.003 16.9 0.1 2.1 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 KXS17888.1 - 0.00041 19.7 0.0 0.00056 19.2 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Glu_dehyd_C PF16912.5 KXS17888.1 - 0.025 14.1 0.0 0.16 11.4 0.0 2.0 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus HI0933_like PF03486.14 KXS17888.1 - 0.063 12.0 0.1 0.092 11.4 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_2 PF00890.24 KXS17888.1 - 0.074 12.1 0.1 0.12 11.5 0.1 1.4 1 1 0 1 1 1 0 FAD binding domain GIDA PF01134.22 KXS17888.1 - 0.23 10.5 0.1 0.31 10.1 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A FMO-like PF00743.19 KXS17890.1 - 7e-41 140.2 0.0 1.9e-30 105.8 0.0 2.6 2 1 1 3 3 3 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KXS17890.1 - 2.4e-18 66.5 0.0 8.7e-15 54.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXS17890.1 - 1.4e-12 47.5 0.0 4.4e-12 45.9 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXS17890.1 - 4e-12 45.9 0.1 2.4e-08 33.5 0.0 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KXS17890.1 - 7.2e-10 39.0 7.0 6.2e-06 26.0 0.5 2.7 2 2 1 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KXS17890.1 - 1.4e-09 38.1 0.9 4.8e-08 33.1 0.1 2.8 2 1 1 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KXS17890.1 - 2.8e-08 33.9 0.3 8.5e-07 29.1 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KXS17890.1 - 1.8e-06 27.4 0.1 0.035 13.4 0.1 2.2 2 0 0 2 2 2 2 Thi4 family Pyr_redox PF00070.27 KXS17890.1 - 1.8e-06 28.4 0.2 0.023 15.3 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KXS17890.1 - 3.1e-06 26.7 0.1 0.00026 20.4 0.0 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.19 KXS17890.1 - 1.3e-05 24.6 0.5 0.00063 19.1 0.7 2.7 2 1 0 2 2 2 1 FAD binding domain NAD_binding_7 PF13241.6 KXS17890.1 - 7.5e-05 23.1 0.1 0.2 12.1 0.1 2.4 2 0 0 2 2 2 2 Putative NAD(P)-binding HI0933_like PF03486.14 KXS17890.1 - 0.00012 20.9 0.1 0.00031 19.6 0.0 1.8 1 1 0 1 1 1 1 HI0933-like protein Glu_dehyd_C PF16912.5 KXS17890.1 - 0.0039 16.7 0.0 0.085 12.3 0.0 2.2 2 0 0 2 2 2 1 Glucose dehydrogenase C-terminus Shikimate_DH PF01488.20 KXS17890.1 - 0.0048 17.0 0.1 4.7 7.3 0.0 2.7 2 1 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase FAD_oxidored PF12831.7 KXS17890.1 - 0.0071 15.7 0.3 0.021 14.2 0.1 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KXS17890.1 - 0.0097 15.0 2.6 0.021 14.0 0.0 2.4 3 0 0 3 3 3 1 FAD binding domain AlaDh_PNT_C PF01262.21 KXS17890.1 - 0.03 13.6 0.2 0.95 8.7 0.0 2.1 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Spermine_synth PF01564.17 KXS17890.1 - 0.088 12.2 0.0 3.9 6.8 0.0 2.2 2 0 0 2 2 2 0 Spermine/spermidine synthase domain Lycopene_cycl PF05834.12 KXS17890.1 - 0.11 11.5 0.3 1.4 7.9 0.0 2.4 3 0 0 3 3 3 0 Lycopene cyclase protein Trp_halogenase PF04820.14 KXS17890.1 - 0.14 10.9 0.7 0.7 8.7 0.0 2.2 3 0 0 3 3 3 0 Tryptophan halogenase TauD PF02668.16 KXS17891.1 - 1.6e-50 172.4 0.5 1.9e-50 172.1 0.5 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family zf-AN1 PF01428.16 KXS17892.1 - 2.7e-19 69.0 23.9 1.6e-11 44.1 7.9 3.1 3 1 1 4 4 4 2 AN1-like Zinc finger Transp_Tc5_C PF04236.15 KXS17892.1 - 0.0086 16.4 5.6 0.0086 16.4 5.6 2.5 3 0 0 3 3 3 2 Tc5 transposase C-terminal domain zf_C2HC_14 PF18574.1 KXS17892.1 - 0.18 11.6 0.8 0.18 11.6 0.8 3.1 4 0 0 4 4 4 0 C2HC Zing finger domain IBR PF01485.21 KXS17892.1 - 0.54 10.5 29.8 5 7.4 14.9 3.1 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain AKAP7_NLS PF10469.9 KXS17893.1 - 3.4e-34 118.6 0.0 4.9e-34 118.0 0.0 1.2 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain DUF4326 PF14216.6 KXS17893.1 - 1.2e-22 80.4 0.0 1.9e-22 79.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4326) Carn_acyltransf PF00755.20 KXS17894.1 - 2.8e-191 637.2 0.0 3.2e-191 637.0 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase ABC_transp_aux PF09822.9 KXS17894.1 - 0.041 13.3 0.0 3.3 7.1 0.0 2.5 3 0 0 3 3 3 0 ABC-type uncharacterized transport system Pribosyltran PF00156.27 KXS17895.1 - 2.2e-22 79.3 0.0 4.6e-22 78.2 0.0 1.5 1 1 0 1 1 1 1 Phosphoribosyl transferase domain PRTase_2 PF15609.6 KXS17895.1 - 0.0038 16.7 0.0 0.0099 15.4 0.0 1.7 2 0 0 2 2 2 1 Phosphoribosyl transferase UPRTase PF14681.6 KXS17895.1 - 0.0043 16.5 0.0 0.0062 16.0 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Aminotran_1_2 PF00155.21 KXS17896.1 - 1.3e-46 159.5 0.0 1.8e-46 159.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II 2OG-FeII_Oxy PF03171.20 KXS17896.1 - 1.1e-26 93.3 0.0 1.7e-13 50.9 0.0 2.6 2 0 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 KXS17896.1 - 1.7e-22 80.3 0.0 7e-11 42.9 0.0 2.5 2 0 0 2 2 2 2 non-haem dioxygenase in morphine synthesis N-terminal TruD PF01142.18 KXS17898.1 - 1.6e-66 224.9 0.0 3.4e-65 220.5 0.0 2.5 2 1 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) Cullin PF00888.22 KXS17899.1 - 1e-180 602.4 5.0 1.3e-180 602.1 5.0 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KXS17899.1 - 1.9e-22 79.0 0.7 1.4e-21 76.2 0.3 2.8 2 0 0 2 2 2 1 Cullin protein neddylation domain TMEM138 PF14935.6 KXS17900.1 - 1.8e-07 31.8 0.0 1.8e-07 31.8 0.0 1.4 2 0 0 2 2 2 1 Transmembrane protein 138 Peptidase_M48 PF01435.18 KXS17901.1 - 3.5e-38 131.3 1.3 1e-37 129.8 0.1 2.2 2 1 0 2 2 2 1 Peptidase family M48 LSM PF01423.22 KXS17902.1 - 1.9e-19 69.1 0.0 2.4e-19 68.8 0.0 1.1 1 0 0 1 1 1 1 LSM domain PX PF00787.24 KXS17903.1 - 3.1e-23 81.9 0.0 8.2e-23 80.6 0.0 1.8 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 KXS17903.1 - 6.7e-10 38.9 6.9 2.8e-06 27.1 2.1 2.8 3 0 0 3 3 3 2 Vps5 C terminal like BAR_3_WASP_bdg PF10456.9 KXS17903.1 - 0.03 13.8 0.1 0.086 12.3 0.0 1.8 2 0 0 2 2 2 0 WASP-binding domain of Sorting nexin protein BAR PF03114.18 KXS17903.1 - 0.049 13.3 6.9 1.8 8.1 0.3 2.8 2 1 1 3 3 3 0 BAR domain GAS PF13851.6 KXS17905.1 - 0.0026 17.1 9.4 0.0026 17.1 9.4 1.9 2 0 0 2 2 2 1 Growth-arrest specific micro-tubule binding HD_2 PF12917.7 KXS17905.1 - 0.042 13.6 5.4 0.89 9.3 3.1 2.1 2 0 0 2 2 2 0 HD containing hydrolase-like enzyme EMP24_GP25L PF01105.24 KXS17905.1 - 0.074 13.0 7.2 0.068 13.1 0.5 2.1 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD TMF_TATA_bd PF12325.8 KXS17905.1 - 1.3 9.2 17.9 0.059 13.6 7.5 2.8 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding 4HBT_3 PF13622.6 KXS17909.1 - 5.7e-27 95.6 0.4 9.1e-27 94.9 0.4 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 KXS17909.1 - 0.03 14.7 0.4 1.5 9.3 0.0 2.8 3 0 0 3 3 3 0 Thioesterase superfamily Wtap PF17098.5 KXS17910.1 - 0.0064 16.4 1.6 0.0098 15.8 1.6 1.3 1 0 0 1 1 1 1 WTAP/Mum2p family Rep_2 PF01719.17 KXS17910.1 - 0.0065 16.3 0.3 0.01 15.6 0.3 1.3 1 0 0 1 1 1 1 Plasmid replication protein Fib_alpha PF08702.10 KXS17910.1 - 0.012 15.8 1.2 0.012 15.8 1.2 1.8 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Med29 PF11568.8 KXS17910.1 - 0.017 15.3 0.8 0.046 14.0 0.4 1.8 1 1 1 2 2 2 0 Mediator complex subunit 29 RNase_H PF00075.24 KXS17910.1 - 0.047 13.9 0.1 0.085 13.0 0.1 1.4 1 0 0 1 1 1 0 RNase H DUF1904 PF08921.11 KXS17910.1 - 0.073 13.4 1.6 0.61 10.4 0.4 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF1904) DUF447 PF04289.12 KXS17910.1 - 0.077 12.8 0.1 0.12 12.1 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF447) Nas2_N PF18265.1 KXS17910.1 - 0.099 12.6 1.4 6.5 6.7 0.2 2.7 1 1 1 2 2 2 0 Nas2 N_terminal domain YgbB PF02542.16 KXS17910.1 - 0.11 12.7 0.1 0.25 11.6 0.1 1.6 1 0 0 1 1 1 0 YgbB family Occludin_ELL PF07303.13 KXS17910.1 - 0.19 12.4 2.1 0.38 11.5 1.6 1.7 2 0 0 2 2 2 0 Occludin homology domain DUF3782 PF12644.7 KXS17910.1 - 0.24 11.6 2.5 0.67 10.1 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3782) Ribosomal_S2 PF00318.20 KXS17911.1 - 2.7e-40 137.9 0.0 3.7e-39 134.2 0.0 2.0 1 1 0 1 1 1 1 Ribosomal protein S2 MFS_1 PF07690.16 KXS17912.1 - 5.1e-27 94.7 32.6 5.1e-27 94.7 32.6 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 KXS17912.1 - 0.00018 20.9 6.2 0.00018 20.9 6.2 2.0 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Ribosomal_L24e PF01246.20 KXS17914.1 - 1.5e-32 111.6 5.3 1.5e-32 111.6 5.3 1.7 2 0 0 2 2 2 1 Ribosomal protein L24e Bromodomain PF00439.25 KXS17915.1 - 4e-20 71.7 0.2 6e-20 71.1 0.2 1.3 1 0 0 1 1 1 1 Bromodomain PSII_Pbs27 PF13326.6 KXS17915.1 - 0.031 14.6 0.1 0.058 13.7 0.1 1.4 1 0 0 1 1 1 0 Photosystem II Pbs27 NADH_Oxid_Nqo15 PF11497.8 KXS17915.1 - 0.047 13.7 0.0 0.08 13.0 0.0 1.4 1 0 0 1 1 1 0 NADH-quinone oxidoreductase chain 15 CLP1_P PF16575.5 KXS17916.1 - 8.7e-28 97.4 0.0 1.5e-27 96.6 0.0 1.4 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop YqgC PF17430.2 KXS17916.1 - 0.035 14.2 0.3 0.099 12.7 0.3 1.8 1 0 0 1 1 1 0 Uncharacterized YqgC-like AAA_14 PF13173.6 KXS17916.1 - 0.097 12.7 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KXS17916.1 - 0.16 12.4 0.0 0.52 10.7 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain F_actin_cap_B PF01115.17 KXS17917.1 - 2.4e-106 354.7 0.0 3e-106 354.4 0.0 1.1 1 0 0 1 1 1 1 F-actin capping protein, beta subunit Xpo1 PF08389.12 KXS17918.1 - 1.2e-05 25.4 0.0 0.0034 17.4 0.0 3.3 3 0 0 3 3 3 2 Exportin 1-like protein IBN_N PF03810.19 KXS17918.1 - 0.19 11.7 0.0 0.67 9.9 0.0 2.0 1 0 0 1 1 1 0 Importin-beta N-terminal domain zf-RING_2 PF13639.6 KXS17920.1 - 8.3e-10 38.9 6.0 1.9e-09 37.7 6.0 1.7 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KXS17920.1 - 2.2e-07 31.1 5.8 5.2e-07 29.9 5.8 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KXS17920.1 - 4.7e-06 26.5 3.7 9.8e-06 25.5 3.7 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KXS17920.1 - 1.3e-05 25.0 4.8 1.3e-05 25.0 4.8 1.7 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXS17920.1 - 6.2e-05 22.9 4.5 0.00012 21.9 4.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 KXS17920.1 - 7.3e-05 22.7 1.7 0.00018 21.5 1.7 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 KXS17920.1 - 0.00034 20.3 4.5 0.00091 18.9 4.5 1.8 1 0 0 1 1 1 1 RING-like zinc finger Zn_ribbon_17 PF17120.5 KXS17920.1 - 0.0066 16.0 4.2 0.019 14.6 4.2 1.8 1 1 0 1 1 1 1 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 KXS17920.1 - 0.0084 16.3 4.3 0.023 14.9 4.3 1.8 1 1 0 1 1 1 1 FANCL C-terminal domain PHD PF00628.29 KXS17920.1 - 0.012 15.4 5.0 0.028 14.3 5.0 1.6 1 0 0 1 1 1 0 PHD-finger RINGv PF12906.7 KXS17920.1 - 0.02 15.0 3.5 0.02 15.0 3.5 1.8 2 0 0 2 2 2 0 RING-variant domain zf-C3HC4_4 PF15227.6 KXS17920.1 - 0.06 13.5 1.8 0.14 12.4 1.8 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Atg14 PF10186.9 KXS17920.1 - 0.072 12.2 2.2 0.13 11.3 2.2 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 zf-C3HC4_2 PF13923.6 KXS17920.1 - 0.083 12.7 11.6 0.036 13.9 7.5 2.5 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) EF-1_beta_acid PF10587.9 KXS17920.1 - 0.1 13.1 0.2 0.1 13.1 0.2 2.1 2 0 0 2 2 1 0 Eukaryotic elongation factor 1 beta central acidic region zf-C3HC4_3 PF13920.6 KXS17920.1 - 0.79 9.6 9.1 1 9.2 6.3 2.3 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_1 PF14446.6 KXS17920.1 - 2.2 8.2 7.4 1.1 9.3 3.0 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Prok-RING_4 PF14447.6 KXS17920.1 - 2.3 8.2 8.2 0.54 10.2 4.1 2.1 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 Pex14_N PF04695.13 KXS17920.1 - 8.6 7.0 14.6 9.5 6.9 5.3 2.5 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF5546 PF17700.1 KXS17923.1 - 0.025 15.0 2.5 0.05 14.0 2.5 1.6 1 1 0 1 1 1 0 Family of unknown function (DUF5546) Pkinase PF00069.25 KXS17924.1 - 5.3e-66 222.7 0.0 6.5e-66 222.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS17924.1 - 4.9e-19 68.6 0.0 6.8e-19 68.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXS17924.1 - 8.2e-08 32.5 0.1 6.6e-06 26.2 0.1 2.6 2 1 1 3 3 3 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXS17924.1 - 0.0059 15.4 0.0 0.015 14.1 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 KXS17924.1 - 0.0072 15.7 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KXS17924.1 - 0.024 14.2 0.2 0.058 13.0 0.2 1.5 1 1 0 1 1 1 0 RIO1 family Choline_kinase PF01633.20 KXS17924.1 - 0.037 13.6 0.1 0.037 13.6 0.1 1.9 2 0 0 2 2 2 0 Choline/ethanolamine kinase Kinase-like PF14531.6 KXS17924.1 - 0.042 13.2 0.0 0.082 12.2 0.0 1.4 1 0 0 1 1 1 0 Kinase-like CBM_1 PF00734.18 KXS17926.1 - 1.8e-07 31.0 10.8 1.8e-07 31.0 10.8 2.4 2 1 0 2 2 2 1 Fungal cellulose binding domain Ephrin_rec_like PF07699.13 KXS17926.1 - 0.009 15.8 1.7 0.038 13.8 0.6 2.2 2 0 0 2 2 2 1 Putative ephrin-receptor like HEM4 PF02602.15 KXS17928.1 - 4.8e-37 127.5 0.1 8e-37 126.8 0.1 1.3 1 1 0 1 1 1 1 Uroporphyrinogen-III synthase HemD SRPRB PF09439.10 KXS17929.1 - 2.7e-39 134.5 0.0 3.3e-39 134.2 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.21 KXS17929.1 - 5.7e-14 52.0 0.0 9.3e-14 51.2 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KXS17929.1 - 9.3e-05 22.0 0.0 0.041 13.4 0.0 2.2 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KXS17929.1 - 0.0002 21.4 0.0 0.00038 20.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 KXS17929.1 - 0.032 14.4 0.0 0.067 13.4 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 KXS17929.1 - 0.052 13.3 0.1 0.12 12.1 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Gtr1_RagA PF04670.12 KXS17929.1 - 0.16 11.3 0.1 0.56 9.5 0.1 1.8 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region PPV_E1_C PF00519.17 KXS17929.1 - 0.16 10.8 0.0 0.22 10.3 0.0 1.1 1 0 0 1 1 1 0 Papillomavirus helicase AAA_23 PF13476.6 KXS17929.1 - 0.16 12.5 0.0 0.29 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF4131 PF13567.6 KXS17929.1 - 0.32 10.6 1.6 0.51 10.0 1.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) NIBRIN_BRCT_II PF16508.5 KXS17930.1 - 9.7e-15 55.0 0.0 2.1e-14 53.9 0.0 1.6 1 0 0 1 1 1 1 Second BRCT domain on Nijmegen syndrome breakage protein FHA PF00498.26 KXS17930.1 - 0.00038 20.7 0.0 0.0008 19.7 0.0 1.6 1 0 0 1 1 1 1 FHA domain RTT107_BRCT_5 PF16770.5 KXS17930.1 - 0.012 15.5 0.0 0.064 13.1 0.0 2.1 2 0 0 2 2 2 0 Regulator of Ty1 transposition protein 107 BRCT domain PTCB-BRCT PF12738.7 KXS17930.1 - 0.019 14.9 0.3 0.69 9.9 0.0 2.4 2 0 0 2 2 2 0 twin BRCT domain NDUF_B7 PF05676.13 KXS17930.1 - 0.22 11.3 0.3 0.44 10.3 0.3 1.4 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cep57_CLD_2 PF14197.6 KXS17932.1 - 0.066 13.3 0.1 0.066 13.3 0.1 6.8 7 1 0 7 7 7 0 Centrosome localisation domain of PPC89 Tropomyosin_1 PF12718.7 KXS17932.1 - 0.11 12.6 42.9 0.044 13.9 5.2 5.5 4 1 1 5 5 5 0 Tropomyosin like Helo_like_N PF17111.5 KXS17932.1 - 0.12 11.7 12.2 0.35 10.2 0.4 2.8 3 0 0 3 3 3 0 Fungal N-terminal domain of STAND proteins RICTOR_N PF14664.6 KXS17933.1 - 0.035 13.1 0.1 0.063 12.2 0.1 1.3 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, N-term DUF2487 PF10673.9 KXS17934.1 - 0.24 11.4 0.0 0.25 11.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2487) Bestrophin PF01062.21 KXS17935.1 - 3.7e-06 26.6 5.0 4.3e-06 26.3 5.0 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel VPDSG-CTERM PF18205.1 KXS17935.1 - 0.16 11.9 3.0 0.36 10.7 3.0 1.6 1 0 0 1 1 1 0 VPDSG-CTERM motif DUF4133 PF13571.6 KXS17935.1 - 0.17 12.2 0.5 0.21 12.0 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4133) Potass_KdpF PF09604.10 KXS17935.1 - 6.9 6.8 8.2 3.5 7.7 1.3 2.3 2 0 0 2 2 2 0 F subunit of K+-transporting ATPase (Potass_KdpF) DJ-1_PfpI PF01965.24 KXS17936.1 - 8e-05 22.5 0.0 0.00042 20.2 0.0 2.4 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 KXS17936.1 - 0.0076 16.0 0.0 0.014 15.1 0.0 1.4 1 1 0 1 1 1 1 ThiJ/PfpI family-like DAGK_cat PF00781.24 KXS17936.1 - 0.0079 15.8 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain NAD_kinase PF01513.21 KXS17936.1 - 0.14 11.3 0.0 0.18 11.0 0.0 1.1 1 0 0 1 1 1 0 ATP-NAD kinase MT-A70 PF05063.14 KXS17938.1 - 1.4e-57 194.3 0.0 2.8e-57 193.4 0.0 1.5 1 0 0 1 1 1 1 MT-A70 Mito_carr PF00153.27 KXS17941.1 - 2.3e-59 197.3 3.9 2.1e-20 72.4 0.4 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein Yae1_N PF09811.9 KXS17942.1 - 5.6e-11 41.9 1.1 8.5e-11 41.4 1.1 1.3 1 0 0 1 1 1 1 Essential protein Yae1, N terminal ADP_PFK_GK PF04587.15 KXS17943.1 - 0.012 14.3 0.1 0.012 14.3 0.1 1.1 1 0 0 1 1 1 0 ADP-specific Phosphofructokinase/Glucokinase conserved region FlaC_arch PF05377.11 KXS17943.1 - 0.018 15.4 0.8 0.11 12.9 0.0 2.2 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) KxDL PF10241.9 KXS17943.1 - 0.05 13.9 1.4 0.16 12.3 0.6 2.1 2 1 0 2 2 2 0 Uncharacterized conserved protein Pkinase PF00069.25 KXS17944.1 - 1.3e-74 250.9 0.0 1.6e-74 250.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS17944.1 - 1.5e-36 126.0 0.0 1.9e-36 125.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXS17944.1 - 1.5e-08 34.3 0.0 1.7e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KXS17944.1 - 0.00012 21.8 0.1 0.00018 21.1 0.1 1.2 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 KXS17944.1 - 0.0044 16.4 0.0 0.0077 15.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KXS17944.1 - 0.016 14.2 0.1 0.019 13.9 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 KXS17944.1 - 0.071 13.0 0.3 0.17 11.8 0.1 1.7 2 1 0 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.25 KXS17945.1 - 1.2e-64 218.3 0.0 1.3e-64 218.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS17945.1 - 1.6e-32 112.9 0.0 2e-32 112.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KXS17945.1 - 0.00022 20.3 0.2 0.00037 19.6 0.2 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KXS17945.1 - 0.00023 20.6 0.0 0.00092 18.6 0.0 1.9 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 KXS17945.1 - 0.0015 18.5 0.3 0.12 12.2 0.0 2.2 1 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KXS17945.1 - 0.053 12.9 0.0 0.084 12.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KXS17945.1 - 0.15 10.8 0.0 0.23 10.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase SMC_N PF02463.19 KXS17946.1 - 6e-58 195.9 41.6 2.1e-56 190.8 41.6 3.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KXS17946.1 - 3.8e-21 75.6 0.2 2.3e-20 73.0 0.2 2.5 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 KXS17946.1 - 4e-16 60.1 3.9 4e-16 60.1 3.9 6.6 2 2 2 4 4 4 1 AAA domain AAA_21 PF13304.6 KXS17946.1 - 4.1e-10 39.9 16.7 4e-05 23.6 0.2 4.1 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SHE3 PF17078.5 KXS17946.1 - 1.9e-05 24.5 11.5 1.9e-05 24.5 11.5 5.6 3 2 2 5 5 5 1 SWI5-dependent HO expression protein 3 AAA_15 PF13175.6 KXS17946.1 - 4.5e-05 23.3 25.5 4.5e-05 23.3 25.5 4.4 2 2 1 3 3 3 1 AAA ATPase domain AAA_29 PF13555.6 KXS17946.1 - 7.6e-05 22.4 0.1 0.00017 21.2 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF4472 PF14739.6 KXS17946.1 - 0.01 16.6 9.0 0.01 16.6 9.0 9.7 4 3 6 10 10 10 0 Domain of unknown function (DUF4472) PRANC PF09372.10 KXS17946.1 - 1.3 9.4 7.9 0.68 10.3 0.5 3.0 2 0 0 2 2 2 0 PRANC domain HrpB7 PF09486.10 KXS17947.1 - 0.19 12.1 4.6 1.7 9.0 0.2 2.3 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) SlyX PF04102.12 KXS17947.1 - 0.89 10.2 4.6 12 6.6 2.3 2.9 3 0 0 3 3 3 0 SlyX ubiquitin PF00240.23 KXS17948.1 - 9.9e-35 118.1 0.4 1.5e-34 117.5 0.4 1.3 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.19 KXS17948.1 - 2.3e-24 85.3 0.8 2.3e-24 85.3 0.8 2.0 2 0 0 2 2 2 1 Ribosomal protein S27a Rad60-SLD PF11976.8 KXS17948.1 - 1.6e-15 56.7 0.4 1.6e-15 56.7 0.4 1.5 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KXS17948.1 - 2.8e-05 24.5 0.1 0.00012 22.4 0.1 1.9 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 KXS17948.1 - 0.00089 19.3 0.6 0.0019 18.3 0.6 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 KXS17948.1 - 0.0066 16.8 0.7 0.012 16.0 0.1 1.7 1 1 1 2 2 2 1 Ubiquitin-like domain TBK1_ULD PF18396.1 KXS17948.1 - 0.0074 16.2 0.0 0.011 15.7 0.0 1.2 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain DUF2407 PF10302.9 KXS17948.1 - 0.009 16.6 0.7 0.013 16.1 0.7 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 KXS17948.1 - 0.11 12.6 0.8 13 5.9 0.0 2.3 2 0 0 2 2 2 0 Ubiquitin-like domain p450 PF00067.22 KXS17949.1 - 6.2e-30 104.3 0.0 7.9e-30 104.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DEAD PF00270.29 KXS17950.1 - 1.2e-46 158.6 0.1 2.6e-46 157.6 0.1 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXS17950.1 - 3.6e-26 91.7 0.0 3.8e-25 88.4 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KXS17950.1 - 1.3e-19 70.1 0.1 2.4e-19 69.3 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ERCC3_RAD25_C PF16203.5 KXS17950.1 - 0.00029 20.1 0.0 0.00052 19.3 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 KXS17950.1 - 0.0013 18.7 0.0 0.0024 17.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PIG-Y PF15159.6 KXS17951.1 - 1.1e-16 61.5 5.4 1.4e-16 61.2 5.4 1.1 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y Glyco_transf_22 PF03901.17 KXS17952.1 - 6.1e-94 315.6 16.9 7.4e-94 315.3 16.9 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family PMT_2 PF13231.6 KXS17952.1 - 9.2 6.5 16.6 5.5 7.2 11.9 2.7 2 1 0 2 2 2 0 Dolichyl-phosphate-mannose-protein mannosyltransferase E1-E2_ATPase PF00122.20 KXS17953.1 - 5e-21 75.0 0.1 5e-21 75.0 0.1 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 KXS17953.1 - 7.1e-16 59.1 0.0 6.8e-10 39.6 0.0 2.6 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KXS17953.1 - 3.2e-05 23.8 0.1 0.15 11.8 0.0 3.4 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KXS17953.1 - 0.00011 22.2 0.0 0.00034 20.7 0.0 1.8 1 0 0 1 1 1 1 Cation transport ATPase (P-type) S6PP PF05116.13 KXS17953.1 - 0.0091 15.6 0.0 0.021 14.4 0.0 1.5 1 0 0 1 1 1 1 Sucrose-6F-phosphate phosphohydrolase AMMECR1 PF01871.17 KXS17954.1 - 1.1e-50 171.5 0.0 1.3e-50 171.3 0.0 1.0 1 0 0 1 1 1 1 AMMECR1 Glycos_transf_1 PF00534.20 KXS17955.1 - 1.8e-14 53.6 0.0 1.2e-12 47.8 0.0 2.3 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KXS17955.1 - 3.5e-12 46.9 0.0 7.2e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 KXS17955.1 - 0.023 15.1 0.0 0.059 13.8 0.0 1.8 1 0 0 1 1 1 0 Glycosyl transferases group 1 Translin PF01997.16 KXS17956.1 - 2.2e-45 155.2 0.1 2.5e-45 155.0 0.1 1.0 1 0 0 1 1 1 1 Translin family Septin PF00735.18 KXS17957.1 - 2.5e-122 407.5 0.4 2.5e-122 407.5 0.4 1.6 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 KXS17957.1 - 1.2e-08 35.0 0.4 3e-08 33.7 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KXS17957.1 - 2.3e-06 27.6 2.0 0.00034 20.6 0.6 3.1 2 1 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 KXS17957.1 - 3e-05 23.6 6.5 0.00032 20.3 0.0 3.0 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 KXS17957.1 - 5.8e-05 23.4 0.0 0.0012 19.1 0.1 2.8 1 1 0 1 1 1 1 AAA domain AIG1 PF04548.16 KXS17957.1 - 8.5e-05 22.0 0.0 8.5e-05 22.0 0.0 2.1 2 0 0 2 2 2 1 AIG1 family Ras PF00071.22 KXS17957.1 - 0.00059 19.5 0.9 0.0018 17.9 0.0 2.1 2 0 0 2 2 2 1 Ras family AAA_16 PF13191.6 KXS17957.1 - 0.0025 18.2 0.0 0.0067 16.8 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain Roc PF08477.13 KXS17957.1 - 0.0044 17.2 0.0 0.0097 16.1 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 KXS17957.1 - 0.0057 16.7 6.3 0.15 12.1 0.2 3.2 2 1 1 3 3 3 1 Dynamin family DUF3584 PF12128.8 KXS17957.1 - 0.022 12.3 8.9 0.11 10.0 8.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) ABC_tran PF00005.27 KXS17957.1 - 0.022 15.2 0.2 0.022 15.2 0.2 2.8 1 1 0 2 2 2 0 ABC transporter DUF5053 PF16476.5 KXS17957.1 - 0.028 14.1 0.1 0.21 11.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5053) AAA_29 PF13555.6 KXS17957.1 - 0.046 13.5 0.0 0.089 12.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 KXS17957.1 - 0.05 12.9 0.0 0.099 12.0 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_24 PF13479.6 KXS17957.1 - 0.09 12.5 0.2 0.27 10.9 0.0 1.9 2 1 0 2 2 2 0 AAA domain Gtr1_RagA PF04670.12 KXS17957.1 - 0.12 11.8 0.0 0.12 11.8 0.0 2.1 3 0 0 3 3 3 0 Gtr1/RagA G protein conserved region YCII PF03795.14 KXS17957.1 - 0.17 12.4 1.1 29 5.2 0.0 2.9 3 0 0 3 3 3 0 YCII-related domain ATP_bind_1 PF03029.17 KXS17957.1 - 2.7 7.7 4.4 24 4.6 0.1 3.0 3 1 1 4 4 4 0 Conserved hypothetical ATP binding protein Strep_SA_rep PF06696.11 KXS17957.1 - 5.7 7.1 12.6 0.12 12.4 1.7 2.7 2 0 0 2 2 2 0 Streptococcal surface antigen repeat UQ_con PF00179.26 KXS17958.1 - 1.8e-50 170.2 0.0 2.1e-50 170.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KXS17958.1 - 2.1e-05 24.3 0.0 2.6e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B Proteasome PF00227.26 KXS17960.1 - 3.7e-39 134.2 0.0 4.1e-39 134.0 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit CBS PF00571.28 KXS17961.1 - 5.9e-21 74.7 12.6 7.5e-06 26.3 0.1 5.2 5 0 0 5 5 5 4 CBS domain PB1 PF00564.24 KXS17961.1 - 1.1e-12 47.7 0.0 2.4e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 PB1 domain DUF4388 PF14332.6 KXS17961.1 - 0.16 12.3 0.0 1.9 8.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4388) FATC PF02260.20 KXS17963.1 - 1.4e-12 47.2 0.1 4.3e-12 45.6 0.1 1.9 2 0 0 2 2 2 1 FATC domain CDC45 PF02724.14 KXS17963.1 - 0.44 8.8 9.4 0.49 8.6 9.4 1.1 1 0 0 1 1 1 0 CDC45-like protein PI3_PI4_kinase PF00454.27 KXS17964.1 - 1.2e-48 166.1 0.0 2.2e-48 165.3 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Baculo_PEP_C PF04513.12 KXS17964.1 - 0.14 12.2 15.4 6.5 6.8 0.6 4.8 4 1 1 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF211 PF02680.14 KXS17964.1 - 0.27 11.4 0.8 4.4 7.5 0.1 3.1 3 0 0 3 3 3 0 Uncharacterized ArCR, COG1888 PMP1_2 PF08114.11 KXS17964.1 - 3.3 7.5 5.0 0.72 9.6 0.4 2.1 2 0 0 2 2 2 0 ATPase proteolipid family Dynamitin PF04912.14 KXS17964.1 - 3.9 6.7 7.9 0.15 11.4 0.3 2.4 3 1 0 3 3 3 0 Dynamitin TBCC_N PF16752.5 KXS17964.1 - 5.3 7.5 6.7 12 6.4 1.4 3.2 3 0 0 3 3 3 0 Tubulin-specific chaperone C N-terminal domain HGTP_anticodon PF03129.20 KXS17966.1 - 2.9e-17 62.6 0.0 8.2e-17 61.1 0.0 1.8 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 KXS17966.1 - 1.6e-08 34.8 0.0 5.2e-08 33.1 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) DSBA PF01323.20 KXS17967.1 - 5.3e-13 49.2 0.0 1.2e-12 48.0 0.0 1.6 1 0 0 1 1 1 1 DSBA-like thioredoxin domain S4 PF01479.25 KXS17968.1 - 8.7e-12 44.6 0.3 2.6e-11 43.0 0.3 1.9 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.6 KXS17968.1 - 0.028 14.2 0.4 0.073 12.9 0.1 1.9 2 0 0 2 2 2 0 S4 domain TGS PF02824.21 KXS17968.1 - 0.13 12.4 0.1 0.41 10.7 0.1 1.9 1 0 0 1 1 1 0 TGS domain DUF2052 PF09747.9 KXS17968.1 - 4.1 7.5 9.7 0.44 10.6 2.3 2.1 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Coilin_N PF15862.5 KXS17968.1 - 7.1 6.4 7.3 0.66 9.8 1.4 2.1 2 0 0 2 2 2 0 Coilin N-terminus Rtf2 PF04641.12 KXS17968.1 - 9.2 5.5 8.5 0.34 10.2 1.7 1.8 2 0 0 2 2 2 0 Rtf2 RING-finger EF-hand_4 PF12763.7 KXS17969.1 - 2.1e-10 40.5 0.0 3.8e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 KXS17969.1 - 0.0046 16.4 0.0 0.0072 15.8 0.0 1.3 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KXS17969.1 - 0.27 11.3 0.0 0.48 10.5 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain DUF4440 PF14534.6 KXS17970.1 - 6.3e-12 45.8 0.0 7.2e-12 45.6 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_2 PF12680.7 KXS17970.1 - 5.1e-05 23.9 0.5 6.6e-05 23.5 0.5 1.2 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_4 PF13577.6 KXS17970.1 - 0.00014 22.0 0.4 0.00024 21.2 0.4 1.4 1 1 0 1 1 1 1 SnoaL-like domain TPR_2 PF07719.17 KXS17971.1 - 6.8e-19 66.4 10.6 0.00047 20.1 0.0 7.0 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.6 KXS17971.1 - 7.3e-15 55.3 38.0 4.2e-06 27.3 3.4 6.8 7 2 1 8 8 8 5 Tetratricopeptide repeat TPR_1 PF00515.28 KXS17971.1 - 5.3e-12 45.0 5.8 0.00025 20.7 0.0 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 KXS17971.1 - 1.4e-10 40.5 5.3 0.00041 20.3 0.0 4.5 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 KXS17971.1 - 1.8e-10 41.2 8.0 0.11 13.0 0.9 6.6 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 KXS17971.1 - 2.6e-07 30.9 30.5 0.045 14.6 0.0 9.6 8 2 2 10 10 9 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KXS17971.1 - 5e-06 26.6 2.6 0.01 16.0 0.2 3.9 3 2 1 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 KXS17971.1 - 0.0001 22.1 6.4 0.04 14.0 0.0 5.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 KXS17971.1 - 0.00019 21.1 1.5 4.3 7.1 0.0 4.8 4 0 0 4 4 4 1 TPR repeat TPR_12 PF13424.6 KXS17971.1 - 0.00071 19.8 0.0 0.00071 19.8 0.0 5.7 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 KXS17971.1 - 0.0078 16.5 0.2 45 4.8 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 KXS17971.1 - 0.031 14.9 11.9 11 6.9 0.0 6.8 8 0 0 8 8 6 0 Tetratricopeptide repeat PPR PF01535.20 KXS17971.1 - 0.065 13.5 1.8 18 5.9 0.0 4.2 5 0 0 5 5 4 0 PPR repeat PknG_TPR PF16918.5 KXS17971.1 - 0.17 10.6 7.2 0.095 11.4 0.2 3.2 2 1 2 4 4 4 0 Protein kinase G tetratricopeptide repeat Glyco_hydro_1 PF00232.18 KXS17974.1 - 9.4e-96 321.0 2.3 1.3e-95 320.5 2.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Cellulase PF00150.18 KXS17974.1 - 2.1e-05 24.1 0.0 0.00072 19.1 0.0 2.2 2 0 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) NUDIX PF00293.28 KXS17975.1 - 4.6e-14 52.6 0.5 8.5e-14 51.7 0.5 1.4 1 0 0 1 1 1 1 NUDIX domain Filament_head PF04732.14 KXS17975.1 - 4.1 8.3 7.1 1.3 9.9 0.3 2.8 3 0 0 3 3 3 0 Intermediate filament head (DNA binding) region SAC3_GANP PF03399.16 KXS17976.1 - 3e-22 79.4 5.2 4.2e-20 72.3 5.2 2.1 1 1 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 KXS17976.1 - 1.4e-05 25.1 0.3 3.5e-05 23.8 0.1 1.7 2 0 0 2 2 2 1 CSN8/PSMD8/EIF3K family TPR_MalT PF17874.1 KXS17976.1 - 0.00059 19.3 0.6 0.00085 18.8 0.6 1.2 1 0 0 1 1 1 1 MalT-like TPR region Cob_adeno_trans PF01923.18 KXS17977.1 - 3e-57 193.3 0.0 3.9e-57 193.0 0.0 1.1 1 0 0 1 1 1 1 Cobalamin adenosyltransferase Suf PF05843.14 KXS17978.1 - 1.6e-56 192.5 3.9 4.9e-49 167.9 0.3 4.5 3 2 0 3 3 3 2 Suppressor of forked protein (Suf) TPR_14 PF13428.6 KXS17978.1 - 2.3e-07 31.0 1.2 0.078 13.8 0.1 5.9 3 2 3 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 KXS17978.1 - 6.7e-05 23.3 3.0 0.53 11.0 0.0 4.2 5 0 0 5 5 5 2 Tetratricopeptide repeat NRDE-2 PF08424.10 KXS17978.1 - 0.00015 21.0 1.9 0.0018 17.5 0.0 2.9 3 0 0 3 3 3 1 NRDE-2, necessary for RNA interference TPR_17 PF13431.6 KXS17978.1 - 0.00021 21.5 0.1 2.5 8.7 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat HAT PF02184.16 KXS17978.1 - 0.016 15.2 0.3 0.88 9.6 0.2 3.4 3 0 0 3 3 3 0 HAT (Half-A-TPR) repeat TPR_16 PF13432.6 KXS17978.1 - 0.024 15.3 0.0 3.4 8.4 0.0 3.2 2 1 0 2 2 2 0 Tetratricopeptide repeat Anticodon_1 PF08264.13 KXS17978.1 - 0.043 13.8 0.1 12 5.8 0.0 2.6 2 0 0 2 2 2 0 Anticodon-binding domain of tRNA BAR PF03114.18 KXS17978.1 - 0.062 12.9 1.1 6.1 6.4 0.1 2.3 2 0 0 2 2 2 0 BAR domain CDC45 PF02724.14 KXS17979.1 - 0.089 11.1 12.4 0.12 10.7 12.4 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF4407 PF14362.6 KXS17979.1 - 3.1 7.0 14.0 0.9 8.8 0.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) FAM76 PF16046.5 KXS17979.1 - 4.9 6.4 20.1 0.14 11.5 1.4 2.3 2 0 0 2 2 2 0 FAM76 protein Porin_3 PF01459.22 KXS17980.1 - 1.8e-46 158.8 0.0 1.5e-29 103.4 0.0 2.5 1 1 1 2 2 2 2 Eukaryotic porin SpoU_methylase PF00588.19 KXS17981.1 - 3.7e-29 101.7 0.0 5.6e-29 101.1 0.0 1.3 1 0 0 1 1 1 1 SpoU rRNA Methylase family DUF1619 PF07773.11 KXS17982.1 - 2.3e-42 146.1 0.0 6.8e-42 144.5 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1619) Vfa1 PF08432.10 KXS17983.1 - 1.1e-20 74.7 0.2 4.1e-17 63.1 0.0 2.0 1 1 1 2 2 2 2 AAA-ATPase Vps4-associated protein 1 Ank_2 PF12796.7 KXS17984.1 - 4.2e-21 75.3 4.6 3.6e-08 33.9 0.8 3.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXS17984.1 - 6.1e-19 66.1 1.6 0.37 11.5 0.1 7.4 6 1 1 7 7 7 6 Ankyrin repeat Ank_4 PF13637.6 KXS17984.1 - 4.6e-16 59.0 2.1 9.6e-06 26.1 0.1 4.5 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 KXS17984.1 - 2.7e-13 49.7 5.9 0.19 12.3 0.1 7.1 6 1 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 KXS17984.1 - 3.6e-10 39.9 5.6 0.0024 18.1 0.5 6.5 2 2 4 6 6 6 3 Ankyrin repeats (many copies) E1_dh PF00676.20 KXS17985.1 - 4.9e-97 324.5 0.1 5.8e-97 324.2 0.1 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 KXS17985.1 - 0.0074 15.5 0.0 0.019 14.2 0.0 1.6 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase ABC_membrane PF00664.23 KXS17986.1 - 3.5e-62 210.5 27.1 5.1e-33 114.9 6.9 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KXS17986.1 - 2e-53 180.6 0.2 1.5e-31 109.7 0.0 3.6 3 0 0 3 3 3 2 ABC transporter SMC_N PF02463.19 KXS17986.1 - 6.2e-08 32.3 4.8 0.0095 15.4 0.0 4.1 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KXS17986.1 - 4.6e-06 26.7 3.6 0.024 14.7 0.5 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.23 KXS17986.1 - 1.4e-05 25.2 2.8 0.0016 18.5 0.6 3.0 3 0 0 3 3 3 1 Dynamin family AAA_16 PF13191.6 KXS17986.1 - 2.7e-05 24.6 0.2 0.11 12.8 0.0 2.7 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 KXS17986.1 - 4e-05 23.3 0.5 0.29 10.9 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain T2SSE PF00437.20 KXS17986.1 - 8.7e-05 21.7 0.1 0.0011 18.1 0.1 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_21 PF13304.6 KXS17986.1 - 0.00012 22.0 7.5 0.21 11.3 0.0 4.0 2 2 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system Zeta_toxin PF06414.12 KXS17986.1 - 0.00083 18.7 0.1 0.11 11.8 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin RsgA_GTPase PF03193.16 KXS17986.1 - 0.002 18.1 3.6 0.097 12.6 0.4 2.4 2 0 0 2 2 2 1 RsgA GTPase DUF815 PF05673.13 KXS17986.1 - 0.0067 15.6 0.0 2 7.5 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF815) cobW PF02492.19 KXS17986.1 - 0.013 15.1 2.2 0.34 10.5 0.3 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.6 KXS17986.1 - 0.027 14.9 0.3 4.1 7.8 0.1 2.5 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 KXS17986.1 - 0.12 12.4 3.0 0.54 10.3 0.1 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_30 PF13604.6 KXS17986.1 - 0.13 12.0 1.7 19 4.9 0.0 3.0 3 0 0 3 3 3 0 AAA domain NB-ARC PF00931.22 KXS17986.1 - 0.15 11.2 0.2 9.2 5.4 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain AAA_22 PF13401.6 KXS17986.1 - 0.16 12.2 1.2 8.1 6.7 0.0 2.7 3 0 0 3 3 2 0 AAA domain AAA_7 PF12775.7 KXS17986.1 - 0.19 11.3 0.3 13 5.2 0.1 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region MeaB PF03308.16 KXS17986.1 - 0.32 10.0 2.1 6.3 5.7 0.4 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AIG1 PF04548.16 KXS17986.1 - 1.9 7.7 3.8 19 4.5 0.7 2.3 2 0 0 2 2 2 0 AIG1 family NUC173 PF08161.12 KXS17988.1 - 5.6e-27 94.7 0.0 1.8e-23 83.3 0.0 3.9 3 1 0 3 3 3 1 NUC173 domain CLASP_N PF12348.8 KXS17988.1 - 9.2e-05 22.1 0.7 0.052 13.1 0.1 3.2 3 1 0 3 3 3 2 CLASP N terminal HEAT_EZ PF13513.6 KXS17988.1 - 0.00012 22.4 8.0 0.26 11.8 0.0 6.2 6 0 0 6 6 6 1 HEAT-like repeat SEEEED PF14797.6 KXS17988.1 - 0.019 15.1 1.3 0.019 15.1 1.3 3.5 4 0 0 4 4 4 0 Serine-rich region of AP3B1, clathrin-adaptor complex IFRD PF05004.13 KXS17988.1 - 0.041 13.0 1.3 0.1 11.7 1.3 1.6 1 0 0 1 1 1 0 Interferon-related developmental regulator (IFRD) Vac14_Fab1_bd PF12755.7 KXS17988.1 - 0.046 14.3 0.0 17 6.1 0.0 3.2 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region HEAT PF02985.22 KXS17988.1 - 0.11 12.8 4.8 7.7 7.1 0.0 5.5 7 0 0 7 7 7 0 HEAT repeat zf-C3HC4_3 PF13920.6 KXS17990.1 - 8e-13 48.0 10.1 8e-13 48.0 10.1 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KXS17990.1 - 2.9e-06 27.0 10.1 6.6e-06 25.9 10.1 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KXS17990.1 - 0.00026 21.2 10.7 0.00026 21.2 10.7 2.2 2 1 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 KXS17990.1 - 0.00086 19.2 10.6 0.00086 19.2 10.6 1.7 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KXS17990.1 - 0.016 15.1 11.5 0.016 15.1 11.5 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 KXS17990.1 - 0.2 11.5 8.9 0.51 10.2 8.9 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_2 PF13923.6 KXS17990.1 - 1.4 8.9 17.3 0.12 12.2 11.6 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-P11 PF03854.14 KXS17990.1 - 4 7.2 9.8 0.57 9.9 5.5 1.7 2 0 0 2 2 2 0 P-11 zinc finger Mto2_bdg PF12808.7 KXS17991.1 - 0.021 15.1 11.7 0.062 13.6 5.6 2.3 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Ax_dynein_light PF10211.9 KXS17991.1 - 0.024 14.6 4.2 0.03 14.3 4.2 1.1 1 0 0 1 1 1 0 Axonemal dynein light chain bZIP_1 PF00170.21 KXS17991.1 - 0.16 12.1 11.3 0.17 12.0 7.1 2.0 1 1 1 2 2 2 0 bZIP transcription factor DivIC PF04977.15 KXS17991.1 - 0.39 10.5 10.9 0.48 10.2 8.7 2.0 1 1 1 2 2 2 0 Septum formation initiator HALZ PF02183.18 KXS17991.1 - 0.87 9.9 13.4 2.1 8.7 6.3 2.4 2 1 0 2 2 2 0 Homeobox associated leucine zipper Sas6_CC PF18594.1 KXS17991.1 - 1.8 8.4 10.2 8.9 6.2 0.3 2.2 2 0 0 2 2 2 0 Sas6/XLF/XRCC4 coiled-coil domain bZIP_2 PF07716.15 KXS17991.1 - 8.2 6.6 14.4 1.7 8.8 7.9 2.1 1 1 1 2 2 2 0 Basic region leucine zipper DnaJ PF00226.31 KXS17992.1 - 4.9e-12 45.8 0.1 3e-08 33.7 0.0 2.2 2 0 0 2 2 2 2 DnaJ domain Katanin_con80 PF13925.6 KXS17992.1 - 0.052 13.6 0.0 0.079 13.0 0.0 1.3 1 0 0 1 1 1 0 con80 domain of Katanin FMN_dh PF01070.18 KXS17994.1 - 2.2e-127 424.9 0.8 2.5e-127 424.7 0.3 1.3 2 0 0 2 2 2 1 FMN-dependent dehydrogenase IMPDH PF00478.25 KXS17994.1 - 8.8e-10 38.1 1.4 4.8e-09 35.7 0.8 2.2 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain DHO_dh PF01180.21 KXS17994.1 - 1.8e-06 27.4 0.7 2.5e-05 23.6 0.2 2.6 2 1 0 2 2 2 1 Dihydroorotate dehydrogenase NMO PF03060.15 KXS17994.1 - 1.1e-05 25.1 0.4 3.6e-05 23.3 0.1 1.9 2 0 0 2 2 2 1 Nitronate monooxygenase Glu_synthase PF01645.17 KXS17994.1 - 1.4e-05 24.4 0.2 5.2e-05 22.6 0.2 2.0 1 1 0 1 1 1 1 Conserved region in glutamate synthase ThiG PF05690.14 KXS17994.1 - 7e-05 22.3 0.3 0.091 12.1 0.0 2.5 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 KXS17994.1 - 0.00033 20.2 0.1 0.0053 16.2 0.0 2.5 1 1 1 2 2 2 1 Histidine biosynthesis protein G3P_antiterm PF04309.12 KXS17994.1 - 0.0013 18.2 0.0 1.1 8.7 0.0 2.6 3 0 0 3 3 3 2 Glycerol-3-phosphate responsive antiterminator Dus PF01207.17 KXS17994.1 - 0.0095 15.1 1.1 1.7 7.6 0.0 3.0 2 1 1 3 3 3 1 Dihydrouridine synthase (Dus) DUF561 PF04481.12 KXS17994.1 - 0.054 12.7 3.8 1.2 8.2 0.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF561) IGPS PF00218.21 KXS17994.1 - 0.055 12.6 0.0 0.48 9.5 0.0 2.3 2 0 0 2 2 2 0 Indole-3-glycerol phosphate synthase B12-binding PF02310.19 KXS17994.1 - 0.062 13.4 0.2 0.74 9.9 0.1 2.4 2 0 0 2 2 2 0 B12 binding domain Pkinase PF00069.25 KXS17995.1 - 0.0032 16.9 0.0 0.0032 16.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain COE1_HLH PF16423.5 KXS17995.1 - 0.067 12.9 0.0 0.097 12.4 0.0 1.3 1 0 0 1 1 1 0 Transcription factor COE1 helix-loop-helix domain Mito_carr PF00153.27 KXS17996.1 - 1.5e-63 210.7 2.7 9.1e-21 73.6 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 KXS17996.1 - 2.4e-22 79.2 5.2 1.6e-10 41.3 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KXS17996.1 - 2.6e-20 70.4 6.1 0.00016 20.9 0.0 4.5 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 KXS17996.1 - 5.2e-20 69.6 7.3 0.00055 19.7 0.0 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KXS17996.1 - 1.9e-13 49.2 7.6 0.00037 19.9 0.1 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 KXS17996.1 - 9.6e-13 47.8 3.5 0.0004 20.2 0.4 4.2 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_10 PF14788.6 KXS17996.1 - 5.7e-06 26.1 3.6 0.53 10.2 0.1 4.1 3 1 1 4 4 4 4 EF hand EF-hand_4 PF12763.7 KXS17996.1 - 4e-05 23.5 0.6 0.0021 18.0 0.2 2.2 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 KXS17996.1 - 0.017 15.4 0.7 0.91 9.9 0.3 2.9 2 1 1 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 KXS17996.1 - 0.031 14.6 0.0 15 6.0 0.0 3.2 3 0 0 3 3 2 0 EF-hand domain Pox_VERT_large PF04441.13 KXS17996.1 - 0.048 11.9 0.2 0.069 11.4 0.2 1.1 1 0 0 1 1 1 0 Poxvirus early transcription factor (VETF), large subunit AAA_33 PF13671.6 KXS17999.1 - 3.2e-13 50.1 0.0 5e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KXS17999.1 - 0.002 18.6 0.0 0.0026 18.1 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 KXS17999.1 - 0.055 12.7 0.1 0.2 10.9 0.0 1.9 1 1 0 1 1 1 0 Zeta toxin NACHT PF05729.12 KXS17999.1 - 0.056 13.4 0.0 0.09 12.7 0.0 1.3 1 0 0 1 1 1 0 NACHT domain CPT PF07931.12 KXS17999.1 - 0.077 12.8 0.1 0.14 12.0 0.1 1.6 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_18 PF13238.6 KXS17999.1 - 0.14 12.7 0.0 0.29 11.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KXS17999.1 - 0.24 11.4 0.0 0.48 10.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Bac_rhodopsin PF01036.18 KXS18000.1 - 4.2e-36 124.6 11.5 5.4e-36 124.2 11.5 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF4149 PF13664.6 KXS18000.1 - 7.7 6.9 9.7 5 7.5 0.3 2.9 2 1 0 3 3 3 0 Domain of unknown function (DUF4149) HAT PF02184.16 KXS18003.1 - 5.2e-26 90.3 83.5 5.3e-13 48.7 0.3 14.4 16 0 0 16 16 16 7 HAT (Half-A-TPR) repeat TPR_14 PF13428.6 KXS18003.1 - 3.9e-23 80.1 17.8 0.054 14.3 0.0 12.1 8 3 5 13 13 12 5 Tetratricopeptide repeat TPR_19 PF14559.6 KXS18003.1 - 1.9e-18 66.7 1.4 0.0031 18.0 0.0 7.7 7 1 1 8 8 7 3 Tetratricopeptide repeat Suf PF05843.14 KXS18003.1 - 2.1e-16 60.8 23.2 0.00011 22.4 4.7 7.2 1 1 5 6 6 6 5 Suppressor of forked protein (Suf) TPR_17 PF13431.6 KXS18003.1 - 2.3e-15 55.7 1.4 2.8e-05 24.2 0.2 6.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 KXS18003.1 - 2.7e-11 43.9 6.8 0.019 15.6 0.1 7.4 7 1 1 8 8 7 3 Tetratricopeptide repeat TPR_2 PF07719.17 KXS18003.1 - 3.2e-11 42.5 22.4 0.71 10.1 0.3 10.5 11 0 0 11 11 10 4 Tetratricopeptide repeat TPR_6 PF13174.6 KXS18003.1 - 3.9e-08 33.4 15.1 1.1 10.0 0.0 9.6 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_8 PF13181.6 KXS18003.1 - 4.6e-06 26.4 14.2 0.15 12.4 0.1 7.6 10 0 0 10 10 7 2 Tetratricopeptide repeat TPR_15 PF13429.6 KXS18003.1 - 2.7e-05 23.5 10.8 0.11 11.7 2.5 4.7 1 1 1 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 KXS18003.1 - 0.00019 21.6 15.1 1.8 8.9 0.2 8.3 8 2 1 9 9 8 1 Tetratricopeptide repeat TPR_7 PF13176.6 KXS18003.1 - 0.00027 20.8 18.3 5.7 7.2 0.1 8.7 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_9 PF13371.6 KXS18003.1 - 0.00057 20.0 11.7 0.72 10.0 0.3 6.4 7 2 1 8 8 7 2 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 KXS18003.1 - 0.0028 17.7 18.7 7.5 6.6 0.4 6.9 4 3 2 6 6 6 1 Mad3/BUB1 homology region 1 TPR_1 PF00515.28 KXS18003.1 - 0.1 12.5 10.3 7.8 6.5 0.0 5.6 5 0 0 5 5 5 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KXS18003.1 - 0.46 10.6 5.6 23 5.1 0.4 4.3 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_11 PF13414.6 KXS18003.1 - 5.2 6.8 7.6 2.2 8.0 0.1 4.0 4 0 0 4 4 4 0 TPR repeat WD40 PF00400.32 KXS18004.1 - 3.9e-43 144.6 12.3 6.8e-08 33.1 0.1 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXS18004.1 - 3.5e-13 49.7 0.1 0.007 16.6 0.0 5.8 1 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KXS18004.1 - 4.8e-06 26.1 0.0 0.0021 17.4 0.0 3.0 2 1 1 3 3 3 1 WD40-like domain DUF5046 PF16465.5 KXS18004.1 - 0.00015 21.3 0.0 1.3 8.4 0.0 3.4 1 1 2 3 3 3 2 Domain of unknown function (DUF5046) PQQ PF01011.21 KXS18004.1 - 0.00053 19.8 0.2 11 6.2 0.0 4.5 4 0 0 4 4 4 1 PQQ enzyme repeat Ge1_WD40 PF16529.5 KXS18004.1 - 0.0018 17.3 0.1 2.3 7.1 0.0 3.4 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_2 PF13360.6 KXS18004.1 - 0.0039 16.8 0.7 0.038 13.6 0.4 2.4 1 1 0 1 1 1 1 PQQ-like domain Nup160 PF11715.8 KXS18004.1 - 0.02 13.6 0.0 40 2.7 0.0 3.7 3 1 1 4 4 4 0 Nucleoporin Nup120/160 PKD PF00801.20 KXS18004.1 - 0.026 14.4 0.6 0.2 11.5 0.0 2.5 3 0 0 3 3 3 0 PKD domain DUF4222 PF13973.6 KXS18004.1 - 0.42 10.2 3.4 4.6 6.9 0.0 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF4222) BPL_N PF09825.9 KXS18005.1 - 1.1e-94 317.6 0.0 4.2e-94 315.7 0.0 1.8 1 1 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.19 KXS18005.1 - 1.2e-16 60.8 0.0 2.3e-16 59.9 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family GATase_3 PF07685.14 KXS18005.1 - 0.0093 15.6 0.1 0.029 14.0 0.0 1.7 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain DJ-1_PfpI PF01965.24 KXS18005.1 - 0.011 15.5 0.0 0.021 14.6 0.0 1.4 1 0 0 1 1 1 0 DJ-1/PfpI family Skp1_POZ PF03931.15 KXS18007.1 - 9.4e-09 35.3 0.0 1.3e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain BTB PF00651.31 KXS18007.1 - 0.037 14.3 0.0 0.052 13.8 0.0 1.3 1 0 0 1 1 1 0 BTB/POZ domain NMT_C PF02799.15 KXS18008.1 - 1.1e-74 250.5 0.0 1.5e-74 250.1 0.0 1.2 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 KXS18008.1 - 2e-74 248.7 0.0 3.3e-74 248.0 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain ECH_1 PF00378.20 KXS18009.1 - 7.7e-29 100.7 0.0 1.5e-28 99.8 0.0 1.5 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXS18009.1 - 6.9e-10 38.9 0.1 8.3e-10 38.7 0.1 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase SAPS PF04499.15 KXS18011.1 - 0.84 8.4 6.7 1 8.1 6.7 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CDC45 PF02724.14 KXS18011.1 - 1.4 7.1 11.1 1.5 7.0 11.1 1.0 1 0 0 1 1 1 0 CDC45-like protein EIF4E-T PF10477.9 KXS18011.1 - 2.7 6.7 16.5 3.4 6.4 16.5 1.0 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E Fasciclin PF02469.22 KXS18012.1 - 6.2e-29 100.8 3.2 2.8e-14 53.4 0.3 2.3 2 0 0 2 2 2 2 Fasciclin domain FMN_dh PF01070.18 KXS18013.1 - 8e-124 413.2 0.1 1e-123 412.8 0.1 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 KXS18013.1 - 1.5e-08 34.0 1.0 6e-08 32.1 0.3 2.2 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 KXS18013.1 - 4.4e-06 26.3 0.9 7.5e-06 25.6 0.9 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase Glu_synthase PF01645.17 KXS18013.1 - 6.7e-06 25.5 0.1 1.2e-05 24.6 0.1 1.5 1 1 0 1 1 1 1 Conserved region in glutamate synthase DHO_dh PF01180.21 KXS18013.1 - 0.00025 20.4 0.0 0.00085 18.6 0.0 1.9 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase His_biosynth PF00977.21 KXS18013.1 - 0.0011 18.5 0.1 0.015 14.8 0.0 2.5 2 1 1 3 3 3 1 Histidine biosynthesis protein ThiG PF05690.14 KXS18013.1 - 0.0039 16.5 4.3 0.2 10.9 0.0 3.2 3 1 1 4 4 4 2 Thiazole biosynthesis protein ThiG G3P_antiterm PF04309.12 KXS18013.1 - 0.068 12.6 0.0 10 5.5 0.0 2.5 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator IGPS PF00218.21 KXS18013.1 - 0.072 12.3 0.0 0.19 10.8 0.0 1.6 2 0 0 2 2 2 0 Indole-3-glycerol phosphate synthase TMP-TENI PF02581.17 KXS18013.1 - 0.14 11.5 0.2 5.6 6.2 0.0 2.4 1 1 1 2 2 2 0 Thiamine monophosphate synthase Usp PF00582.26 KXS18014.1 - 9e-28 97.5 0.1 3e-27 95.8 0.1 1.7 1 1 0 1 1 1 1 Universal stress protein family Peptidase_S41_N PF11918.8 KXS18014.1 - 0.091 13.0 0.0 0.14 12.4 0.0 1.3 1 1 0 1 1 1 0 N-terminal domain of Peptidase_S41 in eukaryotic IRBP Hemagglutinin PF00509.18 KXS18014.1 - 0.15 10.5 0.0 0.19 10.1 0.0 1.1 1 0 0 1 1 1 0 Haemagglutinin NTP_transf_3 PF12804.7 KXS18015.1 - 5e-10 40.0 0.2 1.1e-09 38.9 0.0 1.7 2 0 0 2 2 2 1 MobA-like NTP transferase domain Hexapep PF00132.24 KXS18015.1 - 5e-07 29.2 9.3 0.0045 16.7 1.6 3.7 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.23 KXS18015.1 - 3.2e-06 26.9 0.0 9.9e-06 25.3 0.0 1.6 2 0 0 2 2 2 1 Nucleotidyl transferase DUF4954 PF16314.5 KXS18015.1 - 0.0062 14.7 0.4 0.0093 14.2 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) IspD PF01128.19 KXS18015.1 - 0.095 12.4 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Hexapep_2 PF14602.6 KXS18015.1 - 4.4 7.1 8.2 47 3.9 0.1 3.3 1 1 2 3 3 3 0 Hexapeptide repeat of succinyl-transferase zf-H2C2_2 PF13465.6 KXS18016.1 - 1.9e-13 50.2 15.7 4.4e-06 26.9 0.2 4.0 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.26 KXS18016.1 - 2.5e-12 46.5 16.1 7e-05 23.1 1.3 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXS18016.1 - 2.5e-05 24.7 15.6 0.2 12.6 0.5 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KXS18016.1 - 0.002 18.4 6.1 0.026 14.8 1.8 2.2 1 1 1 2 2 2 2 C2H2-type zinc ribbon FOXP-CC PF16159.5 KXS18016.1 - 0.0021 18.7 3.7 0.61 10.8 0.1 3.1 2 1 1 3 3 3 1 FOXP coiled-coil domain zf-C2H2_11 PF16622.5 KXS18016.1 - 0.33 10.8 7.9 0.44 10.3 1.4 2.5 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-CGNR PF11706.8 KXS18016.1 - 5 7.1 10.5 0.45 10.4 0.8 3.1 3 0 0 3 3 3 0 CGNR zinc finger NUDIX PF00293.28 KXS18018.1 - 8.9e-19 67.8 0.0 1.1e-18 67.6 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 KXS18018.1 - 0.037 14.0 0.0 0.06 13.3 0.0 1.3 1 1 0 1 1 1 0 NUDIX domain Ribosomal_S10 PF00338.22 KXS18019.1 - 3.3e-12 46.5 0.0 4.5e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e YchF-GTPase_C PF06071.13 KXS18020.1 - 1.2e-39 134.4 0.1 2.6e-39 133.3 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 KXS18020.1 - 1.2e-20 73.6 0.0 2.9e-20 72.5 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KXS18020.1 - 3.7e-06 26.5 0.0 7.1e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.21 KXS18020.1 - 0.0078 16.2 0.0 0.023 14.7 0.0 1.7 1 0 0 1 1 1 1 TGS domain FHA PF00498.26 KXS18020.1 - 0.054 13.9 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 FHA domain HEAT_2 PF13646.6 KXS18021.1 - 2.6e-07 30.9 2.4 0.00026 21.3 0.1 2.2 2 1 1 3 3 3 2 HEAT repeats HEAT PF02985.22 KXS18021.1 - 0.0067 16.6 0.9 1.1 9.6 0.0 2.7 2 0 0 2 2 2 2 HEAT repeat PS_Dcarbxylase PF02666.15 KXS18022.1 - 4.4e-66 222.3 0.0 2.8e-64 216.3 0.0 2.2 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase E1_DerP2_DerF2 PF02221.15 KXS18023.1 - 5.8e-23 81.8 0.0 7.9e-23 81.4 0.0 1.1 1 0 0 1 1 1 1 ML domain MG2 PF01835.19 KXS18023.1 - 0.16 12.4 0.0 0.26 11.8 0.0 1.3 1 0 0 1 1 1 0 MG2 domain Arf PF00025.21 KXS18024.1 - 1e-65 220.4 0.0 1.2e-65 220.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 KXS18024.1 - 1.4e-12 47.5 0.0 5e-09 35.8 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 KXS18024.1 - 6.7e-11 41.9 0.0 8.7e-11 41.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 KXS18024.1 - 1.1e-07 32.1 0.0 4.1e-07 30.2 0.0 1.8 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KXS18024.1 - 3.5e-07 30.3 0.0 5e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 KXS18024.1 - 6.5e-07 29.1 0.0 7.5e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KXS18024.1 - 4.3e-05 23.0 0.0 5e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 KXS18024.1 - 0.056 13.2 0.0 0.14 11.9 0.0 1.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.19 KXS18024.1 - 0.17 11.5 0.0 7.4 6.1 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DNA_methylase PF00145.17 KXS18025.1 - 1.8e-42 145.9 0.0 9e-42 143.6 0.0 2.3 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase DNMT1-RFD PF12047.8 KXS18025.1 - 3.1e-16 59.7 3.2 3.7e-12 46.5 0.0 2.9 2 1 1 3 3 3 2 Cytosine specific DNA methyltransferase replication foci domain BAH PF01426.18 KXS18025.1 - 8.8e-11 41.7 0.0 0.0005 19.9 0.0 2.9 2 0 0 2 2 2 2 BAH domain Sec7 PF01369.20 KXS18026.1 - 7.5e-74 247.4 3.3 9.7e-74 247.0 1.1 2.3 2 0 0 2 2 2 1 Sec7 domain Sec7_N PF12783.7 KXS18026.1 - 2.5e-41 141.2 1.3 2.5e-41 141.2 1.3 3.9 4 0 0 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 KXS18026.1 - 1.6e-30 104.8 17.7 4.4e-30 103.4 1.2 5.9 6 0 0 6 6 6 2 Domain of unknown function (DUF1981) DCB PF16213.5 KXS18026.1 - 1.3e-19 70.6 1.3 3.1e-18 66.0 0.0 3.2 3 0 0 3 3 3 1 Dimerisation and cyclophilin-binding domain of Mon2 DUF1539 PF07560.11 KXS18026.1 - 2.9 8.0 6.2 1.8 8.7 0.2 3.7 4 1 1 5 5 5 0 Domain of Unknown Function (DUF1539) CRAL_TRIO PF00650.20 KXS18027.1 - 1.6e-21 76.6 0.0 2.8e-21 75.9 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 KXS18027.1 - 9.7e-05 22.5 0.0 0.00015 21.9 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KXS18027.1 - 0.011 15.9 1.6 0.011 15.9 0.1 1.8 2 0 0 2 2 2 0 CRAL/TRIO, N-terminal domain CbiD PF01888.17 KXS18028.1 - 0.26 10.5 2.3 0.53 9.6 2.3 1.4 1 0 0 1 1 1 0 CbiD LRR_6 PF13516.6 KXS18031.1 - 5.9e-10 38.4 14.8 0.08 13.0 0.7 6.1 6 0 0 6 6 6 4 Leucine Rich repeat LRR_4 PF12799.7 KXS18031.1 - 0.025 15.0 3.1 0.65 10.5 1.9 3.4 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KXS18031.1 - 0.13 12.9 0.9 45 5.2 0.0 4.3 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_8 PF13855.6 KXS18031.1 - 0.23 11.2 7.3 1.7 8.5 1.6 3.7 3 1 0 3 3 3 0 Leucine rich repeat VSP PF03302.13 KXS18032.1 - 0.014 14.2 0.1 0.018 13.9 0.1 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein Gly-zipper_Omp PF13488.6 KXS18032.1 - 0.067 13.2 3.9 0.11 12.5 3.9 1.3 1 0 0 1 1 1 0 Glycine zipper Bacteriocin_IIc PF10439.9 KXS18032.1 - 1 9.5 6.1 1.7 8.8 5.3 1.7 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide MtrF PF09472.10 KXS18032.1 - 4.5 6.8 5.3 6.1 6.3 3.0 2.1 1 1 1 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) adh_short PF00106.25 KXS18033.1 - 1.2e-17 64.0 0.3 1.7e-17 63.6 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXS18033.1 - 6.8e-12 45.4 0.7 8.5e-12 45.1 0.7 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 KXS18033.1 - 0.00087 19.2 1.2 0.0014 18.5 1.2 1.4 1 1 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 KXS18033.1 - 0.0022 18.0 0.2 0.0041 17.0 0.2 1.5 1 1 0 1 1 1 1 KR domain NmrA PF05368.13 KXS18033.1 - 0.071 12.7 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family tRNA-synt_2c PF01411.19 KXS18034.1 - 0.04 12.4 0.0 0.055 12.0 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class II (A) tRNA_SAD PF07973.14 KXS18034.1 - 0.25 11.5 1.7 0.25 11.4 0.3 1.7 2 0 0 2 2 2 0 Threonyl and Alanyl tRNA synthetase second additional domain Sacchrp_dh_NADP PF03435.18 KXS18035.1 - 2.6e-13 50.3 0.2 6e-13 49.2 0.2 1.6 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NmrA PF05368.13 KXS18035.1 - 0.00014 21.5 0.8 0.00029 20.5 0.8 1.5 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXS18035.1 - 0.0067 16.3 1.8 0.44 10.4 1.0 2.2 1 1 1 2 2 2 2 NAD(P)H-binding Epimerase PF01370.21 KXS18035.1 - 0.016 14.6 0.0 0.025 14.1 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 KXS18035.1 - 0.023 15.1 0.0 0.052 14.0 0.0 1.7 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain SIR2 PF02146.17 KXS18036.1 - 8.4e-54 182.2 0.0 1.2e-53 181.7 0.0 1.2 1 0 0 1 1 1 1 Sir2 family GCS PF03074.16 KXS18037.1 - 5e-155 516.4 0.0 1.9e-102 343.3 0.0 2.1 2 0 0 2 2 2 2 Glutamate-cysteine ligase GCS2 PF04107.13 KXS18037.1 - 0.0091 15.4 0.2 0.063 12.6 0.0 2.1 2 0 0 2 2 2 1 Glutamate-cysteine ligase family 2(GCS2) IMUP PF15761.5 KXS18038.1 - 0.1 13.3 3.7 0.35 11.6 3.7 2.0 1 0 0 1 1 1 0 Immortalisation up-regulated protein Serendipity_A PF05482.12 KXS18038.1 - 0.29 9.7 0.4 0.42 9.2 0.4 1.1 1 0 0 1 1 1 0 Serendipity locus alpha protein (SRY-A) WD40 PF00400.32 KXS18040.1 - 1.4e-22 79.5 14.8 4.3e-06 27.4 0.1 6.4 7 0 0 7 7 7 4 WD domain, G-beta repeat Nup160 PF11715.8 KXS18040.1 - 1.4e-06 27.3 0.4 0.0047 15.6 0.0 2.9 2 1 1 3 3 3 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 KXS18040.1 - 2.2e-06 27.9 0.2 0.075 13.3 0.0 4.3 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 KXS18040.1 - 0.016 15.7 0.8 1.1 9.8 0.0 3.9 4 0 0 4 4 4 0 PQQ-like domain Ge1_WD40 PF16529.5 KXS18040.1 - 0.026 13.5 0.6 2.4 7.0 0.0 3.0 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KXS18040.1 - 0.28 10.5 0.0 38 3.5 0.0 3.3 4 0 0 4 4 4 0 WD40-like domain GCV_T PF01571.21 KXS18042.1 - 1.5e-61 208.1 0.0 2e-61 207.6 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain DUF1989 PF09347.10 KXS18042.1 - 6.7e-42 143.0 0.0 3.6e-40 137.3 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF1989) GCV_T_C PF08669.11 KXS18042.1 - 3.2e-12 46.2 0.3 7.6e-12 45.0 0.3 1.7 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain FMO-like PF00743.19 KXS18043.1 - 0.00013 20.6 0.0 0.035 12.5 0.0 2.8 3 0 0 3 3 3 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KXS18043.1 - 0.0018 17.6 0.0 0.23 10.7 0.0 2.8 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXS18043.1 - 0.039 14.2 0.1 2.2 8.6 0.0 2.4 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KXS18043.1 - 0.045 13.7 0.0 0.59 10.1 0.0 2.4 3 0 0 3 3 3 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KXS18043.1 - 0.11 11.7 0.0 0.52 9.5 0.0 2.1 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase MCD PF05292.11 KXS18044.1 - 6.8e-70 235.6 0.0 8.7e-70 235.2 0.0 1.1 1 0 0 1 1 1 1 Malonyl-CoA decarboxylase C-terminal domain Herpes_BBRF1 PF04793.12 KXS18044.1 - 0.19 10.7 0.0 0.33 9.9 0.0 1.3 1 0 0 1 1 1 0 BRRF1-like protein HpcH_HpaI PF03328.14 KXS18045.1 - 2.7e-52 177.1 0.2 3.6e-52 176.7 0.2 1.2 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 KXS18045.1 - 1e-12 47.9 0.0 7.5e-10 38.5 0.0 2.3 2 0 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold DIOX_N PF14226.6 KXS18047.1 - 3.1e-14 53.7 0.0 4.5e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Sen15 PF09631.10 KXS18047.1 - 3.8e-14 52.8 0.0 6.2e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 Sen15 protein DUF5323 PF17257.2 KXS18047.1 - 0.13 12.2 0.7 0.26 11.2 0.7 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5323) MoCF_biosynth PF00994.24 KXS18051.1 - 3.4e-30 104.6 0.0 8.1e-30 103.4 0.0 1.6 1 1 0 1 1 1 1 Probable molybdopterin binding domain RCDG1 PF15725.5 KXS18051.1 - 2.9 8.4 6.8 1.9 9.0 0.5 2.4 2 0 0 2 2 2 0 Renal cancer differentiation gene 1 protein Med15 PF09606.10 KXS18052.1 - 0.024 13.4 9.1 0.029 13.1 9.1 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Pex19 PF04614.12 KXS18052.1 - 0.16 11.7 2.9 0.2 11.4 2.9 1.1 1 0 0 1 1 1 0 Pex19 protein family MFAP1 PF06991.11 KXS18052.1 - 3.5 7.4 8.0 4.5 7.1 8.0 1.1 1 0 0 1 1 1 0 Microfibril-associated/Pre-mRNA processing DUF4407 PF14362.6 KXS18052.1 - 9.5 5.5 13.7 13 5.1 13.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Sld5 PF05916.11 KXS18055.1 - 0.00095 19.6 0.1 0.0016 18.9 0.1 1.4 1 0 0 1 1 1 1 GINS complex protein FKBP_C PF00254.28 KXS18056.1 - 1.9e-33 114.6 0.0 2.7e-26 91.7 0.0 3.7 3 1 0 3 3 3 3 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_9 PF13371.6 KXS18056.1 - 9.6e-06 25.7 0.1 0.00072 19.7 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 KXS18056.1 - 8e-05 22.5 2.5 0.18 12.0 0.2 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_20 PF14561.6 KXS18056.1 - 0.00082 19.7 0.4 0.00082 19.7 0.4 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 KXS18056.1 - 0.0057 17.0 0.1 0.015 15.6 0.1 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.6 KXS18056.1 - 0.013 16.1 5.6 0.017 15.8 0.3 2.8 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 KXS18056.1 - 0.018 15.6 1.9 0.038 14.5 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat FKBP_N_2 PF18023.1 KXS18056.1 - 0.023 14.8 0.0 3.2 7.9 0.0 2.7 2 0 0 2 2 2 0 BDBT FKBP like N-terminal NARP1 PF12569.8 KXS18056.1 - 0.086 11.7 0.1 0.086 11.7 0.1 2.2 1 1 1 2 2 1 0 NMDA receptor-regulated protein 1 TPR_1 PF00515.28 KXS18056.1 - 0.11 12.3 0.1 0.64 9.9 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KXS18056.1 - 0.11 12.7 0.1 0.21 11.8 0.1 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 FlxA PF14282.6 KXS18056.1 - 0.81 9.7 5.8 0.71 9.9 1.3 2.2 2 0 0 2 2 2 0 FlxA-like protein TPR_6 PF13174.6 KXS18056.1 - 8.9 7.2 11.6 1.5 9.6 0.7 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KXS18056.1 - 9.4 7.4 12.1 0.81 10.7 0.7 4.0 3 1 1 4 4 4 0 Tetratricopeptide repeat TolA_bind_tri PF16331.5 KXS18057.1 - 3.2e-06 27.1 5.9 0.0024 17.9 0.3 2.6 1 1 1 2 2 2 2 TolA binding protein trimerisation JIP_LZII PF16471.5 KXS18057.1 - 6.6e-06 26.2 1.8 6.6e-06 26.2 1.8 1.7 2 0 0 2 2 1 1 JNK-interacting protein leucine zipper II ATG16 PF08614.11 KXS18057.1 - 1.1e-05 25.7 3.0 2.3e-05 24.7 3.0 1.4 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.9 KXS18057.1 - 9.5e-05 22.4 1.0 0.00023 21.2 1.0 1.7 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 BRE1 PF08647.11 KXS18057.1 - 0.00025 21.1 0.3 0.00081 19.4 0.1 1.9 2 0 0 2 2 2 1 BRE1 E3 ubiquitin ligase DUF3450 PF11932.8 KXS18057.1 - 0.00046 19.6 1.9 0.00078 18.8 1.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) Atg14 PF10186.9 KXS18057.1 - 0.00068 18.8 1.2 0.00099 18.3 1.2 1.2 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 KASH_CCD PF14662.6 KXS18057.1 - 0.00098 19.0 2.0 0.0019 18.1 2.0 1.4 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH APG6_N PF17675.1 KXS18057.1 - 0.0011 19.4 8.0 0.0024 18.4 8.0 1.8 1 1 0 1 1 1 1 Apg6 coiled-coil region UPF0242 PF06785.11 KXS18057.1 - 0.0013 18.9 0.2 0.0022 18.1 0.2 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus Spc7 PF08317.11 KXS18057.1 - 0.0017 17.3 0.6 0.0026 16.7 0.6 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein bZIP_1 PF00170.21 KXS18057.1 - 0.0029 17.7 1.0 0.34 11.0 0.0 2.4 1 1 1 2 2 2 1 bZIP transcription factor ADIP PF11559.8 KXS18057.1 - 0.0032 17.6 2.9 0.0074 16.4 2.9 1.6 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding GAS PF13851.6 KXS18057.1 - 0.0059 16.0 4.1 0.0059 16.0 4.1 1.7 2 1 0 2 2 1 1 Growth-arrest specific micro-tubule binding LRRFIP PF09738.9 KXS18057.1 - 0.0073 15.8 3.1 0.019 14.5 3.1 1.9 1 1 0 1 1 1 1 LRRFIP family DUF724 PF05266.14 KXS18057.1 - 0.015 15.2 0.5 0.024 14.5 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF4795 PF16043.5 KXS18057.1 - 0.015 14.9 3.7 0.09 12.4 3.6 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) Striatin PF08232.12 KXS18057.1 - 0.017 15.7 0.6 0.017 15.7 0.6 2.1 2 1 1 3 3 2 0 Striatin family bZIP_Maf PF03131.17 KXS18057.1 - 0.02 15.4 4.4 1.8 9.1 0.5 2.7 1 1 1 2 2 2 0 bZIP Maf transcription factor TMF_DNA_bd PF12329.8 KXS18057.1 - 0.024 14.6 0.4 0.057 13.4 0.4 1.7 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Taxilin PF09728.9 KXS18057.1 - 0.027 13.6 0.3 0.027 13.6 0.3 2.5 2 1 1 3 3 3 0 Myosin-like coiled-coil protein Rho_Binding PF08912.11 KXS18057.1 - 0.034 14.9 1.8 9.1 7.2 0.1 2.9 1 1 2 3 3 3 0 Rho Binding PilJ PF13675.6 KXS18057.1 - 0.046 13.7 0.9 0.1 12.7 0.6 1.7 1 1 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term Cnn_1N PF07989.11 KXS18057.1 - 0.073 13.2 3.5 7.2 6.8 0.7 2.7 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 DUF2968 PF11180.8 KXS18057.1 - 0.076 12.6 4.7 0.16 11.6 4.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2968) HAUS-augmin3 PF14932.6 KXS18057.1 - 0.086 12.4 1.6 0.14 11.7 1.6 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 GIT_CC PF16559.5 KXS18057.1 - 0.086 12.7 4.3 1.1 9.2 0.6 2.4 1 1 1 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor DivIVA PF05103.13 KXS18057.1 - 0.1 12.7 2.1 9.4 6.3 0.1 2.3 1 1 1 2 2 2 0 DivIVA protein Nup54 PF13874.6 KXS18057.1 - 0.11 12.6 2.5 0.23 11.5 2.5 1.5 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 DUF1664 PF07889.12 KXS18057.1 - 0.13 12.4 0.9 0.29 11.2 0.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) ZapB PF06005.12 KXS18057.1 - 0.14 12.6 0.4 0.14 12.6 0.4 2.5 2 1 1 3 3 2 0 Cell division protein ZapB Fungal_TACC PF12709.7 KXS18057.1 - 0.22 12.0 2.1 13 6.3 0.3 2.6 1 1 3 4 4 4 0 Fungal Transforming acidic coiled-coil (TACC) proteins YabA PF06156.13 KXS18057.1 - 0.23 12.1 2.2 0.85 10.3 2.2 2.0 1 1 0 1 1 1 0 Initiation control protein YabA ABC_tran_CTD PF16326.5 KXS18057.1 - 0.41 10.9 5.2 0.48 10.7 2.2 2.6 2 1 1 3 3 2 0 ABC transporter C-terminal domain Fez1 PF06818.15 KXS18057.1 - 0.75 10.2 5.9 0.13 12.7 1.8 1.7 2 0 0 2 2 2 0 Fez1 HALZ PF02183.18 KXS18057.1 - 1 9.6 5.5 10 6.4 1.1 3.1 1 1 1 2 2 2 0 Homeobox associated leucine zipper bZIP_2 PF07716.15 KXS18057.1 - 1.3 9.2 10.6 2.4 8.3 0.9 3.2 2 1 1 3 3 3 0 Basic region leucine zipper DUF2205 PF10224.9 KXS18057.1 - 2.4 8.2 7.2 1.3 9.1 2.7 2.6 2 1 1 3 3 3 0 Short coiled-coil protein DivIC PF04977.15 KXS18057.1 - 2.6 7.9 10.3 2.3 8.0 0.4 2.9 2 1 1 3 3 3 0 Septum formation initiator Spc24 PF08286.11 KXS18057.1 - 5 7.4 6.3 12 6.2 3.9 2.5 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 Exo_endo_phos PF03372.23 KXS18058.1 - 9.9e-08 31.8 0.0 2.1e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RhoGAP PF00620.27 KXS18058.1 - 0.0017 18.2 0.0 0.068 13.0 0.0 2.6 2 1 0 2 2 2 1 RhoGAP domain PapD-like PF14874.6 KXS18058.1 - 0.084 13.0 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 Flagellar-associated PapD-like zf-CCHC PF00098.23 KXS18060.1 - 3.7e-08 33.1 2.9 1.5e-07 31.1 2.9 2.2 1 0 0 1 1 1 1 Zinc knuckle gag_pre-integrs PF13976.6 KXS18060.1 - 0.00091 19.0 0.0 0.0023 17.8 0.0 1.7 1 0 0 1 1 1 1 GAG-pre-integrase domain zf-CCHC_6 PF15288.6 KXS18060.1 - 0.1 12.5 1.8 0.27 11.1 1.8 1.7 1 0 0 1 1 1 0 Zinc knuckle Transket_pyr PF02779.24 KXS18065.1 - 9.4e-42 142.7 0.1 1.3e-41 142.2 0.1 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KXS18065.1 - 1.3e-34 118.7 0.0 2.5e-34 117.8 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain Beta-lactamase PF00144.24 KXS18066.1 - 3.3e-32 112.0 0.1 6.2e-32 111.1 0.1 1.4 1 1 0 1 1 1 1 Beta-lactamase Mem_trans PF03547.18 KXS18067.1 - 2.6e-39 134.8 0.1 6.6e-22 77.4 0.0 2.2 2 0 0 2 2 2 2 Membrane transport protein COX8 PF02285.15 KXS18067.1 - 0.13 12.1 0.0 0.36 10.7 0.0 1.7 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIII TRAM_LAG1_CLN8 PF03798.16 KXS18068.1 - 4.6e-40 137.5 15.5 5.2e-40 137.3 15.5 1.0 1 0 0 1 1 1 1 TLC domain DUF1138 PF06592.13 KXS18068.1 - 0.26 11.4 1.6 23 5.2 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1138) AMP-binding PF00501.28 KXS18069.1 - 1.1e-79 268.0 0.0 1.7e-79 267.4 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme DSPc PF00782.20 KXS18070.1 - 4.8e-18 65.3 0.0 4.9e-18 65.2 0.0 1.0 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KXS18070.1 - 0.0029 17.2 0.0 0.003 17.2 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase EBP PF05241.12 KXS18073.1 - 2.3e-19 69.5 7.1 1.5e-18 66.9 7.1 1.9 1 1 0 1 1 1 1 Emopamil binding protein DUF420 PF04238.12 KXS18073.1 - 0.011 16.0 0.5 0.1 12.9 0.5 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF420) PP2C PF00481.21 KXS18075.1 - 1.3e-80 270.7 0.0 1.6e-80 270.4 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 KXS18075.1 - 0.0032 17.4 0.0 0.57 10.1 0.0 2.2 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 KXS18075.1 - 0.053 13.2 0.0 0.12 12.0 0.0 1.7 1 1 0 1 1 1 0 Protein phosphatase 2C Lipase_GDSL PF00657.22 KXS18076.1 - 1.3e-10 41.6 0.0 3e-10 40.4 0.0 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 KXS18076.1 - 3.6e-05 24.2 7.9 7e-05 23.3 7.9 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Ras PF00071.22 KXS18077.1 - 8.9e-54 181.5 0.0 1e-53 181.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXS18077.1 - 9.3e-32 109.8 0.1 1.7e-31 109.0 0.0 1.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXS18077.1 - 1.7e-17 63.4 0.0 2.8e-17 62.7 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KXS18077.1 - 5.6e-06 26.0 0.0 2.3e-05 24.0 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KXS18077.1 - 1.2e-05 24.8 0.0 1.7e-05 24.3 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KXS18077.1 - 2.1e-05 24.6 0.0 3.3e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KXS18077.1 - 0.0022 18.4 0.0 0.0048 17.3 0.0 1.6 1 1 1 2 2 2 1 AAA ATPase domain Septin PF00735.18 KXS18077.1 - 0.0023 17.3 0.0 0.0034 16.7 0.0 1.2 1 0 0 1 1 1 1 Septin SRPRB PF09439.10 KXS18077.1 - 0.003 17.0 0.0 0.01 15.3 0.0 1.7 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_29 PF13555.6 KXS18077.1 - 0.011 15.5 0.1 0.034 13.9 0.1 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 KXS18077.1 - 0.019 15.5 0.0 0.055 14.0 0.0 1.5 1 1 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 KXS18077.1 - 0.03 14.6 0.0 0.076 13.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 KXS18077.1 - 0.031 13.7 0.0 0.05 13.0 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein RsgA_GTPase PF03193.16 KXS18077.1 - 0.033 14.1 0.0 0.11 12.5 0.0 1.8 2 1 0 2 2 2 0 RsgA GTPase NACHT PF05729.12 KXS18077.1 - 0.041 13.8 0.0 0.075 12.9 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_24 PF13479.6 KXS18077.1 - 0.07 12.9 0.0 0.23 11.1 0.0 1.9 2 1 0 2 2 2 0 AAA domain G-alpha PF00503.20 KXS18077.1 - 0.23 10.6 0.5 4 6.5 0.1 2.1 1 1 1 2 2 2 0 G-protein alpha subunit SOUL PF04832.12 KXS18078.1 - 0.079 13.1 0.2 0.17 12.1 0.2 1.5 1 0 0 1 1 1 0 SOUL heme-binding protein F_actin_bund_C PF18060.1 KXS18079.1 - 1.9e-25 88.8 25.7 1.9e-25 88.8 25.7 2.2 1 1 1 2 2 2 1 F actin bundling C terminal EF-hand_7 PF13499.6 KXS18079.1 - 0.005 17.3 2.1 0.012 16.1 0.4 2.3 2 1 0 2 2 2 1 EF-hand domain pair Macoilin PF09726.9 KXS18079.1 - 0.16 10.5 13.1 0.17 10.4 13.1 1.1 1 0 0 1 1 1 0 Macoilin family DUF4407 PF14362.6 KXS18079.1 - 2.4 7.4 10.1 3.5 6.9 10.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Presenilin PF01080.17 KXS18079.1 - 4.9 5.8 8.3 6.7 5.4 8.3 1.1 1 0 0 1 1 1 0 Presenilin TMIE PF16038.5 KXS18079.1 - 6.8 6.6 7.8 24 4.9 7.8 2.0 1 0 0 1 1 1 0 TMIE protein FA_desaturase PF00487.24 KXS18080.1 - 1.8e-35 123.0 16.3 1.8e-35 123.0 16.3 2.0 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.28 KXS18080.1 - 4e-21 74.9 0.0 7.8e-20 70.8 0.0 2.8 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain ELO PF01151.18 KXS18081.1 - 5.2e-58 196.5 12.1 6.4e-58 196.2 12.1 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family F-box-like PF12937.7 KXS18082.1 - 0.1 12.5 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 F-box-like F-box_4 PF15966.5 KXS18082.1 - 0.17 11.8 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 F-box Asp PF00026.23 KXS18083.1 - 1.9e-47 162.2 0.0 2.8e-47 161.7 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KXS18083.1 - 0.00013 22.3 0.2 0.00051 20.3 0.2 1.8 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Mito_carr PF00153.27 KXS18084.1 - 8.3e-59 195.5 0.5 1e-19 70.2 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein MSA-2c PF12238.8 KXS18084.1 - 0.0095 16.0 9.0 0.05 13.6 0.1 2.1 2 0 0 2 2 2 2 Merozoite surface antigen 2c Pheromone PF08015.11 KXS18084.1 - 0.033 15.2 3.8 0.033 15.2 3.8 2.8 3 0 0 3 3 3 0 Fungal mating-type pheromone GREB1 PF15782.5 KXS18084.1 - 0.77 6.8 3.0 1.1 6.4 3.0 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Pyocin_S PF06958.12 KXS18084.1 - 6.2 7.4 7.7 2.8 8.5 0.8 2.3 2 0 0 2 2 2 0 S-type Pyocin RNase_P_Rpp14 PF01900.19 KXS18085.1 - 3e-26 91.6 0.0 4e-26 91.3 0.0 1.2 1 0 0 1 1 1 1 Rpp14/Pop5 family Hemerythrin PF01814.23 KXS18087.1 - 2.2e-05 25.1 9.2 0.00025 21.7 2.6 1.9 1 1 1 2 2 2 2 Hemerythrin HHE cation binding domain Mito_carr PF00153.27 KXS18088.1 - 2.6e-64 213.2 0.1 1e-22 79.9 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein GPI-anchored PF10342.9 KXS18089.1 - 0.0089 16.8 4.7 0.033 14.9 0.4 2.5 2 1 0 2 2 2 2 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family TetR_C_28 PF17937.1 KXS18090.1 - 0.069 13.6 0.1 0.19 12.2 0.1 1.7 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Orexin PF02072.15 KXS18091.1 - 0.049 13.6 0.3 0.086 12.8 0.3 1.3 1 0 0 1 1 1 0 Prepro-orexin Cyclin_N PF00134.23 KXS18091.1 - 0.11 12.2 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Cyclin, N-terminal domain Glyco_hydro_114 PF03537.13 KXS18092.1 - 1.5e-23 83.4 0.0 8.2e-21 74.4 0.0 2.2 1 1 1 2 2 2 2 Glycoside-hydrolase family GH114 PALP PF00291.25 KXS18093.1 - 2.9e-59 200.9 1.0 3.3e-59 200.7 1.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme TusA PF01206.17 KXS18093.1 - 0.033 14.0 0.0 0.098 12.5 0.0 1.8 1 0 0 1 1 1 0 Sulfurtransferase TusA DUF604 PF04646.12 KXS18094.1 - 7.3e-09 35.4 0.0 1.2e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF604 PAN_1 PF00024.26 KXS18094.1 - 4.7e-07 29.7 0.0 8e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 PAN domain Fringe PF02434.16 KXS18094.1 - 1.4e-05 24.6 0.0 1.9e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Fringe-like PAN_4 PF14295.6 KXS18094.1 - 2.6e-05 24.0 0.0 5.7e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 PAN domain Transket_pyr PF02779.24 KXS18095.1 - 3.4e-54 183.2 0.0 5.7e-54 182.5 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 KXS18095.1 - 1.7e-43 148.7 0.0 2.4e-43 148.2 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 KXS18095.1 - 4.7e-39 133.5 0.0 7.4e-39 132.9 0.0 1.3 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal Sel1 PF08238.12 KXS18096.1 - 6.4e-12 45.7 1.9 5.1e-05 23.8 0.1 3.2 3 1 0 3 3 3 2 Sel1 repeat TPR_2 PF07719.17 KXS18096.1 - 0.00012 21.9 1.0 1.7 9.0 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KXS18096.1 - 0.00047 19.9 2.8 1.4 8.9 0.1 3.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 KXS18096.1 - 0.0011 19.0 2.8 8.4 6.9 0.0 3.5 4 0 0 4 4 4 2 Tetratricopeptide repeat CoA_binding_2 PF13380.6 KXS18096.1 - 0.093 13.2 0.0 0.15 12.6 0.0 1.3 1 0 0 1 1 1 0 CoA binding domain TPR_7 PF13176.6 KXS18096.1 - 0.18 11.9 0.8 9.4 6.5 0.0 3.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Pkinase PF00069.25 KXS18097.1 - 1.7e-63 214.5 0.0 2.3e-63 214.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS18097.1 - 9.8e-44 149.6 0.0 1.4e-43 149.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase CNH PF00780.22 KXS18097.1 - 2.3e-20 73.3 0.0 3.2e-13 49.9 0.0 2.7 2 1 0 2 2 2 2 CNH domain Kinase-like PF14531.6 KXS18097.1 - 5.1e-06 26.0 0.0 0.00012 21.6 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KXS18097.1 - 0.00022 20.1 0.0 0.00036 19.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase DOMON PF03351.17 KXS18099.1 - 6.3e-10 39.3 0.1 1.7e-07 31.4 0.0 2.2 2 0 0 2 2 2 2 DOMON domain CDH-cyt PF16010.5 KXS18099.1 - 0.00067 19.4 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase Foamy_virus_ENV PF03408.14 KXS18099.1 - 0.032 12.1 0.0 0.039 11.8 0.0 1.0 1 0 0 1 1 1 0 Foamy virus envelope protein SH3_2 PF07653.17 KXS18100.1 - 4e-12 45.6 0.0 2.5e-10 39.9 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 KXS18100.1 - 6.4e-09 35.3 0.1 1.4e-08 34.2 0.0 1.6 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 KXS18100.1 - 5e-06 26.3 0.0 8.4e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.26 KXS18100.1 - 0.008 16.2 0.7 0.02 15.0 0.7 1.7 1 0 0 1 1 1 1 WW domain RasGEF PF00617.19 KXS18101.1 - 3.9e-48 164.0 0.0 5.7e-48 163.4 0.0 1.2 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KXS18101.1 - 7.5e-19 67.9 0.0 1.4e-18 67.0 0.0 1.4 1 0 0 1 1 1 1 RasGEF N-terminal motif zf-MYND PF01753.18 KXS18102.1 - 9.8e-09 35.2 10.4 1.9e-08 34.2 10.4 1.5 1 0 0 1 1 1 1 MYND finger TPR_9 PF13371.6 KXS18102.1 - 0.007 16.5 0.2 0.022 14.9 0.2 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.6 KXS18102.1 - 0.039 13.6 0.0 0.074 12.7 0.0 1.5 1 0 0 1 1 1 0 TPR repeat TPR_7 PF13176.6 KXS18102.1 - 0.059 13.4 0.5 0.36 11.0 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 KXS18102.1 - 0.12 12.6 0.0 0.58 10.4 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 KXS18102.1 - 3.6 8.3 5.8 9.1 7.0 0.2 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat NDUFA12 PF05071.16 KXS18103.1 - 1.2e-08 35.7 0.0 1.6e-08 35.2 0.0 1.3 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 MSA-2c PF12238.8 KXS18103.1 - 0.15 12.1 0.5 0.19 11.7 0.5 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c Mito_carr PF00153.27 KXS18104.1 - 2e-46 155.8 1.3 2.1e-14 53.2 0.1 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein Formyl_trans_N PF00551.19 KXS18105.1 - 2.5e-36 125.1 0.2 3.3e-36 124.7 0.2 1.1 1 0 0 1 1 1 1 Formyl transferase ACT_4 PF13291.6 KXS18105.1 - 0.0025 18.4 0.0 1.5 9.5 0.0 2.4 2 0 0 2 2 2 2 ACT domain Acetyltransf_1 PF00583.25 KXS18106.1 - 7.6e-17 61.6 0.0 8.7e-17 61.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXS18106.1 - 7.8e-13 48.5 0.0 1e-12 48.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXS18106.1 - 1.3e-11 44.8 0.0 1.7e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KXS18106.1 - 2.2e-05 24.6 0.0 3e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXS18106.1 - 0.0003 20.7 0.0 0.00042 20.2 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 KXS18106.1 - 0.0037 17.3 0.0 0.013 15.6 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.7 KXS18106.1 - 0.0062 16.7 0.1 0.011 15.9 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KXS18106.1 - 0.0077 16.3 0.0 0.018 15.2 0.0 1.6 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase PanZ PF12568.8 KXS18106.1 - 0.031 14.0 0.0 0.036 13.8 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_8 PF13523.6 KXS18106.1 - 0.037 13.7 0.0 0.054 13.2 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF4351 PF14261.6 KXS18106.1 - 0.057 13.5 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4351) Acetyltransf_13 PF13880.6 KXS18106.1 - 0.16 12.0 0.1 0.27 11.2 0.1 1.4 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase IFT46_B_C PF12317.8 KXS18107.1 - 6.2e-68 228.7 0.1 7e-67 225.3 0.1 2.0 1 1 0 1 1 1 1 Intraflagellar transport complex B protein 46 C terminal dsDNA_bind PF01984.20 KXS18108.1 - 2e-30 105.3 3.3 2.4e-30 105.1 3.3 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain MLTR_LBD PF17765.1 KXS18108.1 - 0.026 14.6 0.2 0.029 14.5 0.2 1.1 1 0 0 1 1 1 0 MmyB-like transcription regulator ligand binding domain PCI PF01399.27 KXS18108.1 - 0.05 14.1 0.1 0.07 13.6 0.1 1.2 1 0 0 1 1 1 0 PCI domain Iso_dh PF00180.20 KXS18109.1 - 5.4e-100 334.9 0.0 6.1e-100 334.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase PdxA PF04166.12 KXS18109.1 - 0.091 12.2 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Pyridoxal phosphate biosynthetic protein PdxA ELO PF01151.18 KXS18110.1 - 4e-57 193.6 25.0 4.9e-57 193.3 25.0 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family ADH_zinc_N PF00107.26 KXS18111.1 - 2.2e-14 53.5 0.5 4.8e-14 52.5 0.5 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXS18111.1 - 2.4e-08 33.8 0.2 2.6e-06 27.3 0.0 2.7 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain Epimerase PF01370.21 KXS18111.1 - 0.00086 18.8 0.1 0.0033 16.9 0.1 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KXS18111.1 - 0.0016 18.1 0.1 0.0026 17.4 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.25 KXS18111.1 - 0.03 13.8 0.1 0.058 12.8 0.1 1.5 1 0 0 1 1 1 0 short chain dehydrogenase AlaDh_PNT_C PF01262.21 KXS18111.1 - 0.048 12.9 1.8 0.08 12.2 1.8 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GDP_Man_Dehyd PF16363.5 KXS18111.1 - 0.079 12.3 0.2 0.26 10.7 0.1 1.8 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase FAA_hydrolase PF01557.18 KXS18113.1 - 2.9e-53 180.8 0.0 4e-53 180.3 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 KXS18113.1 - 4.2e-34 116.9 0.0 1.4e-33 115.3 0.0 1.8 2 0 0 2 2 2 1 Fumarylacetoacetase N-terminal RPA_C PF08784.11 KXS18114.1 - 8.2e-13 48.9 0.1 1.1e-11 45.3 0.1 2.2 1 1 0 1 1 1 1 Replication protein A C terminal tRNA_anti-codon PF01336.25 KXS18114.1 - 6.6e-06 26.0 0.1 1.1e-05 25.3 0.1 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Keratin_2_head PF16208.5 KXS18114.1 - 0.0039 17.3 13.6 0.0058 16.8 13.6 1.2 1 0 0 1 1 1 1 Keratin type II head Mito_carr PF00153.27 KXS18115.1 - 3e-28 97.6 8.4 2.1e-14 53.2 0.6 3.3 3 1 0 3 3 3 3 Mitochondrial carrier protein AMP-binding PF00501.28 KXS18116.1 - 2.8e-77 260.1 0.0 3.8e-77 259.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXS18116.1 - 0.065 14.2 0.1 0.15 13.0 0.1 1.7 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain zf_ZIC PF18366.1 KXS18117.1 - 0.11 12.6 0.1 0.18 11.9 0.1 1.3 1 0 0 1 1 1 0 Zic proteins zinc finger domain Thioredoxin PF00085.20 KXS18118.1 - 9.9e-12 44.8 0.0 8.8e-05 22.4 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin Sporozoite_P67 PF05642.11 KXS18118.1 - 0.0033 15.6 3.0 0.0033 15.6 3.0 1.9 2 0 0 2 2 2 1 Sporozoite P67 surface antigen zf-RING_2 PF13639.6 KXS18119.1 - 2.5e-13 50.1 5.3 4.2e-13 49.4 5.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KXS18119.1 - 9.8e-09 34.8 3.3 9.8e-09 34.8 3.3 2.0 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KXS18119.1 - 6.8e-08 32.2 4.8 1.3e-07 31.3 4.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXS18119.1 - 2.3e-07 30.7 2.1 8.4e-07 28.9 0.8 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 KXS18119.1 - 3.3e-07 30.5 5.1 8e-07 29.3 5.1 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KXS18119.1 - 6.8e-07 29.1 2.9 1.1e-06 28.5 2.9 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KXS18119.1 - 1.2e-06 28.2 4.1 2.1e-06 27.5 4.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KXS18119.1 - 1.2e-05 25.0 3.5 2.7e-05 23.9 3.5 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KXS18119.1 - 0.00012 22.0 1.2 0.00029 20.8 1.2 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 KXS18119.1 - 0.00057 19.5 3.5 0.0011 18.6 3.5 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 KXS18119.1 - 0.00079 19.2 3.8 0.0014 18.4 3.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_1 PF14446.6 KXS18119.1 - 0.0068 16.3 4.1 0.051 13.5 0.9 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 zf-RING_4 PF14570.6 KXS18119.1 - 0.017 14.9 3.6 0.03 14.1 3.6 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 KXS18119.1 - 0.062 13.5 3.6 0.21 11.8 3.6 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.6 KXS18119.1 - 0.13 12.5 4.2 0.64 10.2 4.3 2.0 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING NCE101 PF11654.8 KXS18119.1 - 0.15 11.8 0.1 0.41 10.4 0.1 1.7 1 0 0 1 1 1 0 Non-classical export protein 1 RINGv PF12906.7 KXS18119.1 - 0.18 12.0 4.5 0.33 11.1 4.5 1.5 1 0 0 1 1 1 0 RING-variant domain zf-C3H2C3 PF17122.5 KXS18119.1 - 0.2 11.7 1.9 0.51 10.4 1.9 1.7 1 0 0 1 1 1 0 Zinc-finger Zf_RING PF16744.5 KXS18119.1 - 0.34 11.0 3.6 1.1 9.5 3.6 1.8 1 1 0 1 1 1 0 KIAA1045 RING finger zf-Nse PF11789.8 KXS18119.1 - 0.37 10.6 2.7 2.7 7.9 2.4 2.1 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit FYVE PF01363.21 KXS18119.1 - 0.56 10.4 2.2 1.4 9.2 2.2 1.5 1 1 0 1 1 1 0 FYVE zinc finger RasGEF PF00617.19 KXS18120.1 - 4e-10 40.2 0.0 6.6e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 RasGEF domain RRM_8 PF11835.8 KXS18120.1 - 0.1 12.8 0.1 0.21 11.8 0.1 1.4 1 0 0 1 1 1 0 RRM-like domain F-box-like PF12937.7 KXS18121.1 - 5.4e-05 23.0 3.3 0.00013 21.8 3.3 1.7 1 0 0 1 1 1 1 F-box-like DUF4129 PF13559.6 KXS18122.1 - 0.066 13.5 0.1 0.072 13.4 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4129) RhoGEF PF00621.20 KXS18123.1 - 8.1e-42 143.5 0.6 1.3e-41 142.8 0.6 1.2 1 0 0 1 1 1 1 RhoGEF domain PH_13 PF16652.5 KXS18123.1 - 0.0063 16.3 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain IQ_SEC7_PH PF16453.5 KXS18123.1 - 0.033 14.2 0.0 0.098 12.6 0.0 1.8 1 0 0 1 1 1 0 PH domain dCache_1 PF02743.18 KXS18124.1 - 1.3e-06 28.4 2.6 3.4e-06 27.0 2.6 1.7 2 0 0 2 2 2 1 Cache domain zf-C2H2_aberr PF17017.5 KXS18125.1 - 0.00023 21.4 5.7 0.001 19.3 0.6 2.1 2 0 0 2 2 2 2 Aberrant zinc-finger zf-C2H2 PF00096.26 KXS18125.1 - 0.0039 17.6 10.6 0.094 13.2 0.2 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXS18125.1 - 0.0075 17.0 6.7 1 10.4 2.7 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-BED PF02892.15 KXS18125.1 - 1.3 9.1 6.0 17 5.5 3.8 2.4 2 0 0 2 2 2 0 BED zinc finger EMP24_GP25L PF01105.24 KXS18126.1 - 9.3e-48 162.6 0.0 1.2e-47 162.2 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Asp4 PF16996.5 KXS18126.1 - 0.036 13.8 1.0 0.082 12.7 0.3 1.9 1 1 1 2 2 2 0 Accessory secretory protein Sec Asp4 HEAT_EZ PF13513.6 KXS18127.1 - 0.00013 22.4 9.4 0.24 11.9 0.1 5.6 5 0 0 5 5 5 2 HEAT-like repeat Arm PF00514.23 KXS18127.1 - 0.00019 21.3 19.1 0.046 13.8 0.0 5.9 7 0 0 7 7 7 2 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 KXS18127.1 - 0.0033 17.8 2.1 0.041 14.3 0.4 3.5 2 2 1 3 3 3 2 HEAT repeats Adaptin_N PF01602.20 KXS18127.1 - 0.0067 15.0 0.6 0.4 9.2 0.1 2.4 2 0 0 2 2 2 2 Adaptin N terminal region Drf_GBD PF06371.13 KXS18127.1 - 0.029 13.9 0.0 0.061 12.9 0.0 1.5 1 0 0 1 1 1 0 Diaphanous GTPase-binding Domain NucS PF01939.16 KXS18127.1 - 0.13 11.6 0.2 0.31 10.3 0.2 1.7 1 0 0 1 1 1 0 Endonuclease NucS HEAT PF02985.22 KXS18127.1 - 2.3 8.7 6.2 8.5 6.9 0.1 4.2 4 0 0 4 4 4 0 HEAT repeat C1ORF64 PF15547.6 KXS18128.1 - 7e-05 23.3 0.0 1.1 9.7 0.0 3.2 4 0 0 4 4 4 2 Steroid receptor-associated and regulated protein OMPdecase PF00215.24 KXS18128.1 - 0.028 14.0 0.1 7.4 6.1 0.0 2.3 2 0 0 2 2 2 0 Orotidine 5'-phosphate decarboxylase / HUMPS family SpoVAB PF13782.6 KXS18128.1 - 9.2 6.6 10.7 13 6.1 1.4 3.0 3 0 0 3 3 3 0 Stage V sporulation protein AB PLA2_B PF01735.18 KXS18129.1 - 1.1e-19 70.3 2.7 6.6e-10 38.0 1.6 3.0 3 0 0 3 3 3 2 Lysophospholipase catalytic domain FAM212 PF15342.6 KXS18129.1 - 0.044 13.6 0.6 1.1 9.1 0.0 3.0 2 0 0 2 2 2 0 FAM212 family MFS_1 PF07690.16 KXS18130.1 - 1.1e-49 169.2 56.6 2.6e-49 168.0 54.3 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXS18130.1 - 3e-15 56.0 13.0 3e-15 56.0 13.0 2.8 4 0 0 4 4 4 1 Sugar (and other) transporter TRI12 PF06609.13 KXS18130.1 - 1.2e-13 50.4 27.1 2.4e-13 49.4 27.1 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2919 PF11143.8 KXS18130.1 - 0.057 13.8 0.2 0.057 13.8 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2919) RdRP PF05183.12 KXS18132.1 - 3.1e-40 138.4 0.0 4e-40 138.0 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase NAD_binding_2 PF03446.15 KXS18134.1 - 2.9e-31 108.8 0.1 4.3e-31 108.2 0.1 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KXS18134.1 - 9.3e-31 106.6 0.1 1.9e-30 105.6 0.0 1.6 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase PDH PF02153.17 KXS18134.1 - 0.00092 18.3 0.0 0.0013 17.8 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydrogenase F420_oxidored PF03807.17 KXS18134.1 - 0.0045 17.5 0.1 0.0092 16.5 0.1 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent zf-C2H2_aberr PF17017.5 KXS18135.1 - 5e-08 33.3 1.2 0.0035 17.5 0.1 2.4 2 0 0 2 2 2 2 Aberrant zinc-finger zf-C2H2 PF00096.26 KXS18135.1 - 0.0004 20.7 8.0 0.0019 18.6 0.3 3.3 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXS18135.1 - 0.087 13.7 0.3 0.087 13.7 0.3 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger zf-BED PF02892.15 KXS18135.1 - 0.14 12.2 2.1 8.8 6.4 0.1 2.5 2 0 0 2 2 2 0 BED zinc finger zf-C2H2_12 PF18658.1 KXS18135.1 - 0.29 10.7 0.9 10 5.8 0.0 2.9 3 0 0 3 3 3 0 Zinc-finger C2H2-type zf-H2C2_2 PF13465.6 KXS18135.1 - 7 7.3 5.7 23 5.6 0.1 3.7 4 0 0 4 4 4 0 Zinc-finger double domain C2 PF00168.30 KXS18137.1 - 4e-24 84.9 0.1 3.1e-13 49.9 0.0 2.4 2 0 0 2 2 2 2 C2 domain MT-A70 PF05063.14 KXS18138.1 - 4.9e-33 114.5 0.0 1.2e-21 77.4 0.0 2.2 2 0 0 2 2 2 2 MT-A70 Cpn60_TCP1 PF00118.24 KXS18139.1 - 1.1e-90 304.6 0.1 2.1e-90 303.7 0.1 1.4 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family Chlorosome_CsmC PF11098.8 KXS18139.1 - 0.74 9.8 10.2 0.57 10.2 1.4 3.6 2 1 1 3 3 3 0 Chlorosome envelope protein C Cpn10 PF00166.21 KXS18140.1 - 1.1e-27 96.0 0.0 1.2e-27 95.8 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit BTB PF00651.31 KXS18142.1 - 1.4e-07 31.7 0.0 2.8e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Pkinase PF00069.25 KXS18143.1 - 2.2e-54 184.6 0.0 8.7e-43 146.6 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXS18143.1 - 3.9e-35 121.4 0.0 2.1e-31 109.2 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase NCD1 PF04904.13 KXS18143.1 - 0.00044 20.2 0.0 0.00081 19.3 0.0 1.4 1 0 0 1 1 1 1 NAB conserved region 1 (NCD1) Kdo PF06293.14 KXS18143.1 - 0.024 14.0 0.0 0.045 13.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Cyclin_N PF00134.23 KXS18144.1 - 3.3e-11 43.0 0.1 1.1e-10 41.3 0.0 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain EF-hand_6 PF13405.6 KXS18145.1 - 3.2e-20 70.3 17.9 0.021 14.7 0.1 9.0 8 0 0 8 8 8 6 EF-hand domain EF-hand_7 PF13499.6 KXS18145.1 - 1.7e-18 66.8 12.1 0.035 14.6 0.0 7.8 7 0 0 7 7 7 6 EF-hand domain pair EF-hand_1 PF00036.32 KXS18145.1 - 1.9e-14 52.0 8.9 0.033 13.7 0.0 8.6 9 0 0 9 9 9 5 EF hand EF-hand_8 PF13833.6 KXS18145.1 - 1.5e-13 50.4 7.4 2.3e-06 27.3 0.1 6.2 6 0 0 6 6 6 3 EF-hand domain pair RST PF12174.8 KXS18145.1 - 1.1e-11 44.5 9.7 0.0089 15.9 0.4 6.2 7 0 0 7 7 7 3 RCD1-SRO-TAF4 (RST) plant domain EF-hand_11 PF08976.11 KXS18145.1 - 5e-06 27.3 10.3 0.49 11.3 0.0 5.9 7 0 0 7 7 7 2 EF-hand domain ECH_1 PF00378.20 KXS18146.1 - 2e-82 276.3 0.8 2.4e-82 276.0 0.8 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXS18146.1 - 1e-33 117.3 0.4 2.8e-33 115.8 0.4 1.7 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 KXS18146.1 - 0.079 12.9 0.1 0.54 10.2 0.0 2.1 2 0 0 2 2 2 0 Peptidase family S49 Ammonium_transp PF00909.21 KXS18147.1 - 1.7e-107 359.6 27.1 1.9e-107 359.4 27.1 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family ATG16 PF08614.11 KXS18148.1 - 0.0014 18.9 1.1 0.22 11.8 0.7 2.5 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) HAP1_N PF04849.13 KXS18148.1 - 0.012 14.8 2.3 0.94 8.6 0.1 2.3 2 0 0 2 2 2 0 HAP1 N-terminal conserved region DUF812 PF05667.11 KXS18148.1 - 0.019 13.9 0.1 0.092 11.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF812) MAD PF05557.13 KXS18148.1 - 0.053 11.9 0.6 0.094 11.1 0.6 1.3 1 0 0 1 1 1 0 Mitotic checkpoint protein SlyX PF04102.12 KXS18148.1 - 0.18 12.4 5.5 0.11 13.1 2.8 2.1 2 0 0 2 2 2 0 SlyX Laminin_II PF06009.12 KXS18148.1 - 0.23 11.5 1.0 0.49 10.4 0.7 1.6 2 0 0 2 2 2 0 Laminin Domain II Tropomyosin PF00261.20 KXS18148.1 - 0.46 9.8 8.3 0.043 13.2 3.2 1.8 2 0 0 2 2 2 0 Tropomyosin Filament PF00038.21 KXS18148.1 - 1.2 8.6 6.4 0.13 11.8 1.8 1.6 2 0 0 2 2 2 0 Intermediate filament protein TPR_MLP1_2 PF07926.12 KXS18148.1 - 3.3 7.8 11.8 0.81 9.8 5.1 2.3 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein T3SSipB PF16535.5 KXS18148.1 - 7.3 7.1 9.4 0.086 13.3 1.2 1.9 2 0 0 2 2 2 0 Type III cell invasion protein SipB G-patch PF01585.23 KXS18149.1 - 6e-17 61.3 1.1 1.3e-16 60.2 1.1 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KXS18149.1 - 0.00062 19.8 1.0 0.00062 19.8 1.0 1.8 2 0 0 2 2 2 1 G-patch domain UCMA PF17085.5 KXS18149.1 - 0.12 12.4 1.2 0.18 11.8 1.2 1.2 1 0 0 1 1 1 0 Unique cartilage matrix associated protein AA_permease_2 PF13520.6 KXS18150.1 - 2.6e-43 148.4 55.4 3.3e-43 148.1 55.4 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXS18150.1 - 1.1e-21 77.1 49.6 1.3e-21 76.7 49.6 1.0 1 0 0 1 1 1 1 Amino acid permease DUF3109 PF11307.8 KXS18152.1 - 0.042 13.7 0.2 0.042 13.7 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3109) DUF5479 PF17575.2 KXS18152.1 - 0.11 13.1 0.1 0.12 12.9 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5479) Response_reg PF00072.24 KXS18156.1 - 2e-23 82.7 0.2 4e-22 78.5 0.2 2.3 1 1 0 1 1 1 1 Response regulator receiver domain DUF4411 PF14367.6 KXS18156.1 - 0.0092 15.9 0.0 0.52 10.2 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4411) DSBA PF01323.20 KXS18157.1 - 1.2e-23 83.9 0.0 1.4e-23 83.7 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain LRR_6 PF13516.6 KXS18158.1 - 5.6e-06 26.0 2.0 1.5 9.1 0.1 4.5 4 0 0 4 4 4 2 Leucine Rich repeat F-box-like PF12937.7 KXS18158.1 - 0.00077 19.3 0.1 0.00077 19.3 0.1 2.5 3 0 0 3 3 3 1 F-box-like LRR_4 PF12799.7 KXS18158.1 - 0.00094 19.5 0.2 0.18 12.3 0.0 3.3 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXS18158.1 - 1.3 8.8 7.1 8 6.3 0.0 4.2 4 0 0 4 4 4 0 Leucine rich repeat WD40 PF00400.32 KXS18159.1 - 0.0017 19.2 3.3 5.9 7.9 0.1 3.9 3 0 0 3 3 3 2 WD domain, G-beta repeat RRM_1 PF00076.22 KXS18160.1 - 7.8e-12 44.8 0.0 1.3e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 KXS18160.1 - 1.9e-09 37.9 7.7 1.9e-09 37.9 7.7 2.6 2 1 0 2 2 2 1 C-terminal duplication domain of Friend of PRMT1 RRM_3 PF08777.11 KXS18160.1 - 0.14 12.3 0.0 0.28 11.3 0.0 1.5 1 1 0 1 1 1 0 RNA binding motif F-box-like PF12937.7 KXS18161.1 - 3.4e-14 52.5 0.1 6.6e-14 51.5 0.1 1.5 1 0 0 1 1 1 1 F-box-like DUF525 PF04379.14 KXS18161.1 - 8.9e-13 48.3 0.0 1.9e-12 47.3 0.0 1.6 1 0 0 1 1 1 1 ApaG domain F-box PF00646.33 KXS18161.1 - 2.3e-08 33.7 0.0 4.9e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 F-box domain ABC_tran PF00005.27 KXS18162.1 - 2.8e-33 115.3 0.0 4.8e-33 114.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 KXS18162.1 - 2.6e-32 112.6 11.4 3.4e-32 112.2 11.4 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.6 KXS18162.1 - 3e-05 24.0 0.1 0.01 15.7 0.0 2.3 1 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KXS18162.1 - 6.5e-05 22.5 0.1 0.0039 16.6 0.1 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_24 PF13479.6 KXS18162.1 - 0.0012 18.6 0.0 0.0023 17.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KXS18162.1 - 0.0014 19.0 0.0 0.0044 17.4 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KXS18162.1 - 0.0057 16.9 0.0 0.016 15.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 KXS18162.1 - 0.0064 16.3 0.0 0.014 15.2 0.0 1.5 1 0 0 1 1 1 1 Cytidylate kinase Rad17 PF03215.15 KXS18162.1 - 0.0096 15.9 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_28 PF13521.6 KXS18162.1 - 0.016 15.4 0.1 0.19 11.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KXS18162.1 - 0.04 13.2 0.0 0.16 11.2 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin AAA_29 PF13555.6 KXS18162.1 - 0.047 13.4 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_15 PF13175.6 KXS18162.1 - 0.048 13.4 0.0 0.076 12.7 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain PRK PF00485.18 KXS18162.1 - 0.064 13.0 0.0 0.2 11.4 0.0 1.8 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.6 KXS18162.1 - 0.075 13.2 0.0 0.26 11.5 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KXS18162.1 - 0.09 12.3 0.0 0.22 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KXS18162.1 - 0.15 12.6 0.0 0.35 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 KXS18162.1 - 0.18 11.9 0.0 0.48 10.5 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase SOG2 PF10428.9 KXS18162.1 - 0.23 10.6 4.3 0.33 10.1 4.3 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Fra10Ac1 PF09725.9 KXS18163.1 - 1.5e-46 157.5 0.1 2.6e-46 156.8 0.1 1.4 1 0 0 1 1 1 1 Folate-sensitive fragile site protein Fra10Ac1 MPM1 PF17234.2 KXS18163.1 - 0.079 13.2 2.5 0.16 12.2 2.5 1.6 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 MscS_TM PF12794.7 KXS18163.1 - 0.5 9.2 3.4 0.79 8.5 3.4 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 4HBT PF03061.22 KXS18164.1 - 0.0045 17.3 0.0 0.0082 16.5 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily Abhydrolase_3 PF07859.13 KXS18165.1 - 3e-19 69.7 0.0 4.1e-19 69.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KXS18165.1 - 2.5e-17 62.9 0.2 6.4e-17 61.6 0.2 1.6 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 KXS18165.1 - 3.5e-08 33.2 0.0 6.8e-07 29.0 0.0 2.2 1 1 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 KXS18165.1 - 8.9e-06 25.5 0.0 0.058 13.0 0.0 2.1 2 0 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.20 KXS18165.1 - 0.0064 16.2 0.1 0.031 13.9 0.2 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold FSH1 PF03959.13 KXS18165.1 - 0.017 14.8 0.0 0.057 13.1 0.0 1.7 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Hydrolase_4 PF12146.8 KXS18165.1 - 0.057 12.7 0.0 0.59 9.4 0.0 2.2 1 1 0 1 1 1 0 Serine aminopeptidase, S33 Cyclase PF04199.13 KXS18166.1 - 8.5e-15 55.2 0.0 1.1e-14 54.8 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase DUF5490 PF17593.2 KXS18166.1 - 0.068 13.2 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5490) DIM1 PF02966.16 KXS18167.1 - 4.9e-67 223.8 0.1 5.5e-67 223.6 0.1 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 KXS18167.1 - 2.6e-06 27.3 0.1 3.4e-06 27.0 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 KXS18167.1 - 0.013 15.7 0.0 0.023 14.9 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_8 PF13905.6 KXS18167.1 - 0.075 13.4 0.2 0.12 12.7 0.2 1.4 1 1 0 1 1 1 0 Thioredoxin-like Acetyltransf_3 PF13302.7 KXS18168.1 - 2.8e-16 60.4 0.0 4.9e-16 59.7 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KXS18168.1 - 0.044 13.5 0.9 1.5 8.5 0.2 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Epimerase PF01370.21 KXS18170.1 - 2.8e-18 66.3 0.0 5.8e-18 65.2 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXS18170.1 - 5.4e-08 32.6 0.2 0.0067 15.9 0.0 2.4 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase NmrA PF05368.13 KXS18170.1 - 2.8e-05 23.8 0.1 0.00055 19.6 0.1 2.1 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.6 KXS18170.1 - 3.4e-05 23.8 0.0 6.9e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding ApbA PF02558.16 KXS18170.1 - 0.01 15.5 0.1 0.17 11.5 0.1 2.6 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA RmlD_sub_bind PF04321.17 KXS18170.1 - 0.034 13.2 0.0 0.13 11.3 0.0 1.9 1 1 0 1 1 1 0 RmlD substrate binding domain 4HBT_3 PF13622.6 KXS18171.1 - 5.5e-38 131.6 0.4 7e-38 131.3 0.4 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 KXS18171.1 - 0.0026 18.1 0.0 1.1 9.7 0.0 2.5 2 0 0 2 2 2 2 Thioesterase superfamily SURF4 PF02077.15 KXS18172.1 - 3.2e-83 279.4 6.2 3.7e-83 279.2 6.2 1.0 1 0 0 1 1 1 1 SURF4 family NMN_transporter PF04973.12 KXS18172.1 - 0.003 17.5 12.0 0.003 17.5 12.0 1.5 1 1 0 1 1 1 1 Nicotinamide mononucleotide transporter HR_lesion PF05514.11 KXS18172.1 - 0.011 15.9 0.7 0.011 15.9 0.7 2.1 2 0 0 2 2 2 0 HR-like lesion-inducing DUF4203 PF13886.6 KXS18172.1 - 0.016 14.9 1.3 0.016 14.9 1.3 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4203) DoxX PF07681.12 KXS18172.1 - 0.035 14.7 5.3 0.035 14.7 5.3 3.4 2 2 1 3 3 3 0 DoxX UPF0014 PF03649.13 KXS18172.1 - 1.8 7.8 10.2 4.2 6.7 5.1 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0014) DUF3021 PF11457.8 KXS18172.1 - 2 8.7 10.6 1.8 8.9 8.9 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3021) DUF5090 PF17009.5 KXS18172.1 - 2.4 8.1 5.3 0.32 10.9 1.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5090) JmjC PF02373.22 KXS18174.1 - 4e-10 40.1 0.0 8.2e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 KXS18174.1 - 0.089 12.5 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 Cupin domain DUF2013 PF09431.10 KXS18175.1 - 2e-37 128.4 4.6 4e-37 127.5 4.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2013) Pro_isomerase PF00160.21 KXS18176.1 - 5e-53 179.6 0.0 5.7e-53 179.4 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD B12-binding PF02310.19 KXS18177.1 - 0.026 14.6 0.0 0.046 13.7 0.0 1.4 1 0 0 1 1 1 0 B12 binding domain PBP PF01161.20 KXS18178.1 - 2.6e-16 60.1 0.4 5e-16 59.2 0.4 1.4 1 1 0 1 1 1 1 Phosphatidylethanolamine-binding protein TOM20_plant PF06552.12 KXS18180.1 - 0.095 12.4 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Plant specific mitochondrial import receptor subunit TOM20 Myb_DNA-binding PF00249.31 KXS18184.1 - 7.9e-05 22.8 0.0 0.00015 21.9 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain RR_TM4-6 PF06459.12 KXS18185.1 - 3 7.6 7.7 3.6 7.4 7.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Asp PF00026.23 KXS18186.1 - 1.2e-106 356.7 0.0 1.4e-106 356.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KXS18186.1 - 7.2e-13 49.1 0.5 2.7e-10 40.8 0.4 2.6 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.6 KXS18186.1 - 0.0011 19.5 0.0 0.23 12.1 0.0 2.4 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 KXS18186.1 - 0.0044 16.8 0.0 0.026 14.3 0.0 2.2 3 0 0 3 3 3 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 KXS18186.1 - 0.0059 17.2 0.1 4.4 8.0 0.0 2.5 2 1 0 2 2 2 2 Aspartyl protease Mito_carr PF00153.27 KXS18187.1 - 1.1e-57 192.0 2.5 1e-19 70.2 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein MIP PF00230.20 KXS18188.1 - 8.4e-41 140.1 17.3 1.2e-24 87.2 11.1 2.0 2 0 0 2 2 2 2 Major intrinsic protein Bac_DnaA PF00308.18 KXS18188.1 - 0.086 12.7 0.1 0.15 11.8 0.1 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein DUF2929 PF11151.8 KXS18188.1 - 0.17 12.2 0.1 0.17 12.2 0.1 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF2929) DUF2208 PF09973.9 KXS18188.1 - 0.53 9.9 3.6 2.9 7.5 0.3 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2208) Pribosyltran PF00156.27 KXS18189.1 - 4e-18 65.4 0.0 6e-18 64.9 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain TFIIS_C PF01096.18 KXS18190.1 - 1.5e-22 79.1 6.9 1.5e-22 79.1 6.9 2.7 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 KXS18190.1 - 9.6e-09 35.0 2.0 9.6e-09 35.0 2.0 3.0 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.7 KXS18190.1 - 1.1e-07 31.7 6.8 0.00014 21.8 1.5 2.3 2 0 0 2 2 2 2 Transposase zinc-ribbon domain TF_Zn_Ribbon PF08271.12 KXS18190.1 - 0.00025 20.5 7.9 0.032 13.8 0.3 2.6 2 1 0 2 2 2 2 TFIIB zinc-binding Baculo_LEF5_C PF11792.8 KXS18190.1 - 0.00053 19.6 0.6 0.00053 19.6 0.6 2.2 2 0 0 2 2 2 1 Baculoviridae late expression factor 5 C-terminal domain zf-RRPl_C4 PF17026.5 KXS18190.1 - 0.0006 19.9 3.1 0.0008 19.5 3.1 1.1 1 0 0 1 1 1 1 Putative ribonucleoprotein zinc-finger pf C4 type DZR PF12773.7 KXS18190.1 - 0.00079 19.4 9.9 0.14 12.2 0.3 2.4 2 1 0 2 2 2 2 Double zinc ribbon DpnI PF06044.12 KXS18190.1 - 0.0042 16.8 0.3 0.0042 16.8 0.3 2.1 1 1 1 2 2 2 1 Dam-replacing family Terminase_GpA PF05876.12 KXS18190.1 - 0.0099 14.5 1.1 0.011 14.3 1.1 1.2 1 0 0 1 1 1 1 Phage terminase large subunit (GpA) zinc-ribbons_6 PF07191.12 KXS18190.1 - 0.038 14.0 9.0 0.36 10.8 0.2 2.4 2 1 0 2 2 2 0 zinc-ribbons DNA_ligase_ZBD PF03119.16 KXS18190.1 - 0.065 13.3 0.4 0.065 13.3 0.4 2.7 3 0 0 3 3 2 0 NAD-dependent DNA ligase C4 zinc finger domain PhnA_Zn_Ribbon PF08274.12 KXS18190.1 - 0.12 12.4 0.2 0.12 12.4 0.2 2.8 3 0 0 3 3 3 0 PhnA Zinc-Ribbon zf-WRNIP1_ubi PF18279.1 KXS18190.1 - 0.13 12.9 2.6 16 6.4 0.5 2.6 2 0 0 2 2 2 0 Werner helicase-interacting protein 1 ubiquitin-binding domain zf-GRF PF06839.12 KXS18190.1 - 0.14 12.3 8.2 0.26 11.4 1.7 2.4 2 0 0 2 2 2 0 GRF zinc finger DUF2387 PF09526.10 KXS18190.1 - 0.16 12.1 5.3 0.45 10.7 1.2 2.2 2 0 0 2 2 2 0 Probable metal-binding protein (DUF2387) HypA PF01155.19 KXS18190.1 - 0.16 12.0 5.8 0.56 10.2 0.3 2.8 1 1 1 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Lar_restr_allev PF14354.6 KXS18190.1 - 0.17 12.3 6.6 2.5 8.5 1.5 2.3 2 0 0 2 2 2 0 Restriction alleviation protein Lar Rad50_zn_hook PF04423.14 KXS18190.1 - 0.22 11.4 2.9 1.8 8.4 0.1 2.3 2 0 0 2 2 2 0 Rad50 zinc hook motif zinc_ribbon_4 PF13717.6 KXS18190.1 - 0.28 11.1 14.1 0.8 9.7 0.4 3.9 4 0 0 4 4 4 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 KXS18190.1 - 0.42 10.1 10.3 13 5.3 0.1 3.8 4 0 0 4 4 4 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 KXS18190.1 - 0.46 10.7 14.3 6.9 6.9 0.9 4.3 3 1 0 4 4 4 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 KXS18190.1 - 0.62 10.6 11.5 6.5 7.4 0.6 4.1 4 0 0 4 4 4 0 Zinc-finger double domain Desulfoferrod_N PF06397.12 KXS18190.1 - 0.74 9.5 6.0 4.3 7.0 0.2 2.7 2 1 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain zinc_ribbon_15 PF17032.5 KXS18190.1 - 0.91 10.3 10.7 0.18 12.5 0.7 2.9 1 1 1 3 3 3 0 zinc-ribbon family zinc_ribbon_2 PF13240.6 KXS18190.1 - 0.94 9.3 13.7 5.2 6.9 0.1 3.9 4 0 0 4 4 4 0 zinc-ribbon domain OrfB_Zn_ribbon PF07282.11 KXS18190.1 - 1 9.4 8.5 4.4 7.3 0.2 2.9 2 1 1 3 3 3 0 Putative transposase DNA-binding domain zf-C4_Topoisom PF01396.19 KXS18190.1 - 1.2 9.0 10.9 0.59 10.0 1.4 3.0 3 0 0 3 3 3 0 Topoisomerase DNA binding C4 zinc finger C1_2 PF03107.16 KXS18190.1 - 1.2 9.5 11.5 0.35 11.2 1.2 2.8 2 1 0 2 2 2 0 C1 domain Zn_ribbon_SprT PF17283.2 KXS18190.1 - 1.6 8.7 17.7 8.1 6.5 0.3 4.0 3 1 1 4 4 4 0 SprT-like zinc ribbon domain zinc_ribbon_10 PF10058.9 KXS18190.1 - 2.4 8.0 10.9 0.11 12.2 1.4 2.8 2 2 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein PADR1 PF08063.12 KXS18190.1 - 4.7 7.1 12.9 2.6 7.9 1.4 2.8 2 1 0 2 2 2 0 PADR1 (NUC008) domain EMP24_GP25L PF01105.24 KXS18191.1 - 8.1e-19 68.3 0.0 9.7e-19 68.0 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD PPR_2 PF13041.6 KXS18192.1 - 2.8e-32 110.7 0.0 4.5e-09 36.4 0.0 5.8 4 1 1 5 5 5 3 PPR repeat family PPR_3 PF13812.6 KXS18192.1 - 1.5e-28 98.7 0.0 2.3e-07 30.8 0.0 5.5 3 2 2 5 5 5 4 Pentatricopeptide repeat domain PPR PF01535.20 KXS18192.1 - 9.4e-21 72.6 0.4 7.7e-05 22.7 0.0 7.6 7 1 0 7 7 7 5 PPR repeat PPR_1 PF12854.7 KXS18192.1 - 4.5e-19 67.9 0.0 0.0014 18.3 0.0 7.7 8 0 0 8 8 8 4 PPR repeat PPR_long PF17177.4 KXS18192.1 - 5e-19 68.5 0.0 8.1e-13 48.2 0.0 2.4 1 1 1 2 2 2 2 Pentacotripeptide-repeat region of PRORP MeaB PF03308.16 KXS18193.1 - 9.5e-89 296.9 0.0 1.5e-88 296.3 0.0 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 KXS18193.1 - 1.9e-05 24.3 0.0 5e-05 23.0 0.0 1.7 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 KXS18193.1 - 9.4e-05 22.7 0.5 0.0011 19.3 0.0 2.6 3 0 0 3 3 3 1 AAA domain ATP_bind_1 PF03029.17 KXS18193.1 - 0.0016 18.2 0.0 0.0047 16.7 0.0 1.7 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_24 PF13479.6 KXS18193.1 - 0.0023 17.7 0.0 0.0055 16.4 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KXS18193.1 - 0.011 15.4 0.0 0.025 14.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.6 KXS18193.1 - 0.02 14.6 0.0 0.042 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KXS18193.1 - 0.039 13.9 0.0 0.076 12.9 0.0 1.5 1 0 0 1 1 1 0 NTPase MMR_HSR1 PF01926.23 KXS18193.1 - 0.039 14.0 0.0 0.083 13.0 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_18 PF13238.6 KXS18193.1 - 0.044 14.3 0.0 0.1 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain CLP1_P PF16575.5 KXS18193.1 - 0.066 13.0 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop ArsA_ATPase PF02374.15 KXS18193.1 - 0.075 12.2 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Anion-transporting ATPase CbiA PF01656.23 KXS18193.1 - 0.1 12.7 0.0 0.23 11.5 0.0 1.6 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain IstB_IS21 PF01695.17 KXS18193.1 - 0.1 12.3 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein O-FucT PF10250.9 KXS18194.1 - 2e-11 44.2 0.0 0.00027 20.7 0.0 3.8 2 1 0 2 2 2 2 GDP-fucose protein O-fucosyltransferase Arf PF00025.21 KXS18195.1 - 1.8e-76 255.5 0.1 2e-76 255.3 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KXS18195.1 - 4.5e-16 59.2 0.1 5.8e-16 58.8 0.1 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KXS18195.1 - 6.6e-14 51.8 0.0 7.6e-14 51.6 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 KXS18195.1 - 2.3e-13 50.0 0.0 2.8e-13 49.7 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KXS18195.1 - 2.1e-12 46.9 1.6 1.4e-08 34.3 0.2 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 KXS18195.1 - 2.1e-10 40.3 0.1 2.7e-10 40.0 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KXS18195.1 - 4.4e-05 23.5 0.0 6.5e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 KXS18195.1 - 0.018 14.4 0.1 0.033 13.5 0.1 1.4 1 0 0 1 1 1 0 6-phosphofructo-2-kinase FeoB_N PF02421.18 KXS18195.1 - 0.37 10.3 1.6 1 8.9 1.6 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B Med9 PF07544.13 KXS18196.1 - 3e-07 30.4 0.3 4.3e-07 29.9 0.3 1.2 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 ECH_1 PF00378.20 KXS18199.1 - 1e-46 159.3 0.0 1.3e-46 159.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXS18199.1 - 1.2e-27 97.3 0.0 1.4e-27 97.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase CK_II_beta PF01214.18 KXS18200.1 - 2.1e-78 262.3 0.0 2.8e-78 261.9 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit DUF1610 PF07754.11 KXS18200.1 - 0.19 11.8 0.3 0.53 10.3 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1610) ECH_1 PF00378.20 KXS18201.1 - 2.6e-42 144.9 0.0 3.5e-42 144.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXS18201.1 - 7.5e-23 81.6 0.0 8.8e-23 81.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase NAD_binding_10 PF13460.6 KXS18202.1 - 7.8e-13 48.7 0.0 1.1e-12 48.2 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KXS18202.1 - 3.5e-11 43.1 0.0 5.3e-11 42.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 KXS18202.1 - 0.0055 15.7 0.0 0.01 14.9 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KXS18202.1 - 0.057 12.9 0.0 0.28 10.6 0.0 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Nramp PF01566.18 KXS18203.1 - 2.7e-111 372.0 11.0 4.6e-66 223.2 0.7 2.3 2 0 0 2 2 2 2 Natural resistance-associated macrophage protein MBOAT PF03062.19 KXS18204.1 - 3.3e-22 79.3 16.7 6.3e-22 78.4 16.7 1.5 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 KXS18204.1 - 0.06 13.6 4.7 0.17 12.2 4.7 1.8 1 0 0 1 1 1 0 Membrane bound O-acyl transferase family TRAP-gamma PF07074.12 KXS18204.1 - 2 7.9 5.0 1.2 8.7 0.8 2.7 3 0 0 3 3 3 0 Translocon-associated protein, gamma subunit (TRAP-gamma) Terminase_5 PF06056.12 KXS18204.1 - 4.2 7.3 5.8 1.6 8.7 2.3 2.1 2 0 0 2 2 2 0 Putative ATPase subunit of terminase (gpP-like) MgsA_C PF12002.8 KXS18205.1 - 1.4e-56 191.1 0.2 3.1e-56 189.9 0.0 1.7 2 0 0 2 2 2 1 MgsA AAA+ ATPase C terminal AAA_assoc_2 PF16193.5 KXS18205.1 - 4.5e-23 81.4 0.1 9e-23 80.4 0.1 1.5 1 0 0 1 1 1 1 AAA C-terminal domain AAA PF00004.29 KXS18205.1 - 4.1e-11 43.4 0.0 7.7e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KXS18205.1 - 1.4e-09 37.9 0.0 3.8e-09 36.5 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KXS18205.1 - 6.2e-05 23.4 0.1 0.032 14.6 0.0 2.6 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KXS18205.1 - 0.0023 18.2 0.1 0.26 11.5 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 KXS18205.1 - 0.0088 16.0 0.1 0.057 13.4 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 KXS18205.1 - 0.024 13.8 0.0 0.04 13.1 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain Mg_chelatase PF01078.21 KXS18205.1 - 0.03 13.7 0.0 0.27 10.6 0.0 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KXS18205.1 - 0.034 14.0 0.0 0.061 13.2 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KXS18205.1 - 0.044 14.3 0.0 0.11 13.0 0.0 1.7 2 0 0 2 2 1 0 AAA domain ResIII PF04851.15 KXS18205.1 - 0.057 13.4 0.0 9.4 6.2 0.0 2.2 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit AFG1_ATPase PF03969.16 KXS18205.1 - 0.11 11.4 0.0 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 AFG1-like ATPase TniB PF05621.11 KXS18205.1 - 0.19 11.1 0.0 0.42 10.0 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein Sigma54_activat PF00158.26 KXS18205.1 - 0.19 11.4 0.0 6.6 6.4 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain MMM1 PF10296.9 KXS18206.1 - 4.6e-41 141.0 0.0 4.6e-28 98.2 0.0 3.0 3 0 0 3 3 3 3 Maintenance of mitochondrial morphology protein 1 LMWPc PF01451.21 KXS18207.1 - 4.6e-43 147.0 0.0 5.2e-43 146.8 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase G6PD_C PF02781.16 KXS18208.1 - 1.9e-109 365.4 0.0 2.5e-109 365.0 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 KXS18208.1 - 3e-58 197.4 0.0 1.5e-57 195.1 0.0 1.9 2 0 0 2 2 2 1 Glucose-6-phosphate dehydrogenase, NAD binding domain GATA PF00320.27 KXS18209.1 - 1.3e-12 47.1 3.6 2.6e-12 46.1 3.6 1.5 1 0 0 1 1 1 1 GATA zinc finger Zn-ribbon_8 PF09723.10 KXS18209.1 - 0.01 16.0 0.1 0.026 14.6 0.1 1.7 1 0 0 1 1 1 1 Zinc ribbon domain DZR PF12773.7 KXS18209.1 - 0.032 14.2 0.9 0.34 11.0 0.9 2.4 1 1 0 1 1 1 0 Double zinc ribbon Vps36-NZF-N PF16988.5 KXS18209.1 - 0.67 9.4 4.9 9.4 5.7 0.2 3.2 2 1 1 3 3 3 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain MerR_2 PF13591.6 KXS18210.1 - 0.094 12.6 0.2 0.17 11.8 0.2 1.4 1 0 0 1 1 1 0 MerR HTH family regulatory protein Ribosomal_L1 PF00687.21 KXS18211.1 - 2.5e-49 167.8 1.9 3.1e-49 167.5 1.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family DUF3671 PF12420.8 KXS18211.1 - 0.14 12.2 3.2 0.21 11.6 3.1 1.6 1 1 0 1 1 1 0 Protein of unknown function PI3_PI4_kinase PF00454.27 KXS18212.1 - 4.2e-32 111.9 0.0 3e-31 109.1 0.0 2.1 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 KXS18212.1 - 0.00079 18.9 0.1 0.0015 18.0 0.1 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) DUF4135 PF13575.6 KXS18212.1 - 0.026 13.9 0.0 0.05 12.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) Cyclin_C_2 PF16899.5 KXS18213.1 - 4.3e-11 43.1 0.0 1.1e-10 41.8 0.0 1.8 1 1 0 1 1 1 1 Cyclin C-terminal domain Rrn6 PF10214.9 KXS18213.1 - 0.03 12.8 5.9 0.041 12.4 5.9 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Ctr PF04145.15 KXS18214.1 - 7.7e-12 46.1 0.5 8e-12 46.0 0.5 1.1 1 0 0 1 1 1 1 Ctr copper transporter family Methyltransf_25 PF13649.6 KXS18215.1 - 2.4e-06 28.2 0.0 3.7e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXS18215.1 - 0.00013 22.6 0.0 0.00021 21.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KXS18215.1 - 0.00041 19.7 0.0 0.00061 19.2 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase RrnaAD PF00398.20 KXS18215.1 - 0.0005 19.2 0.0 0.00067 18.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase PrmA PF06325.13 KXS18215.1 - 0.00052 19.5 0.0 0.00067 19.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 KXS18215.1 - 0.0026 17.6 0.0 0.0032 17.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 KXS18215.1 - 0.0046 16.5 0.0 0.0071 15.9 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 MetW PF07021.12 KXS18215.1 - 0.013 15.1 0.1 0.019 14.6 0.1 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_31 PF13847.6 KXS18215.1 - 0.021 14.6 0.0 0.03 14.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 KXS18215.1 - 0.021 14.6 0.0 0.03 14.1 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 KXS18215.1 - 0.038 13.5 0.0 0.066 12.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Cons_hypoth95 PF03602.15 KXS18215.1 - 0.045 13.4 0.0 0.066 12.9 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_12 PF08242.12 KXS18215.1 - 0.069 13.9 0.0 0.1 13.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain LPD7 PF18821.1 KXS18215.1 - 0.14 12.3 0.0 0.3 11.2 0.0 1.5 1 0 0 1 1 1 0 Large polyvalent protein-associated domain 7 Methyltransf_4 PF02390.17 KXS18215.1 - 0.16 11.5 0.0 0.23 10.9 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase GTP_EFTU PF00009.27 KXS18217.1 - 2.2e-13 50.2 0.0 8.2e-10 38.5 0.0 2.2 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Arf PF00025.21 KXS18217.1 - 0.25 10.8 0.0 0.76 9.2 0.0 1.7 2 0 0 2 2 2 0 ADP-ribosylation factor family TRAM_LAG1_CLN8 PF03798.16 KXS18218.1 - 6.9e-31 107.5 26.3 8.3e-31 107.3 26.3 1.0 1 0 0 1 1 1 1 TLC domain CBM26 PF16738.5 KXS18218.1 - 0.13 12.6 2.7 0.29 11.4 2.7 1.5 1 0 0 1 1 1 0 Starch-binding module 26 HpcH_HpaI PF03328.14 KXS18219.1 - 7.4e-36 123.4 0.1 1e-35 122.9 0.1 1.2 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 KXS18219.1 - 3.1e-09 36.4 0.0 2.2e-07 30.3 0.0 2.7 1 1 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold PEPcase_2 PF14010.6 KXS18219.1 - 0.015 13.9 0.1 0.021 13.3 0.1 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase UIM PF02809.20 KXS18220.1 - 0.025 14.5 3.1 0.053 13.5 3.1 1.6 1 0 0 1 1 1 0 Ubiquitin interaction motif PgaD PF13994.6 KXS18220.1 - 0.044 13.8 0.1 0.18 11.8 0.0 1.9 2 0 0 2 2 2 0 PgaD-like protein Corazonin PF17308.2 KXS18220.1 - 0.1 12.9 0.0 0.24 11.7 0.0 1.6 1 0 0 1 1 1 0 Pro-corazonin CAP_N PF01213.19 KXS18220.1 - 3.8 6.9 9.4 7.4 6.0 9.4 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DAP PF15228.6 KXS18221.1 - 0.3 12.3 2.2 1.1 10.4 1.1 2.2 1 1 1 2 2 2 0 Death-associated protein SNF2_N PF00176.23 KXS18222.1 - 7.6e-65 218.9 0.0 1.3e-64 218.2 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF3535 PF12054.8 KXS18222.1 - 8.3e-49 167.0 0.0 3.5e-47 161.6 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3535) Helicase_C PF00271.31 KXS18222.1 - 1.8e-17 63.7 0.0 4e-17 62.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT PF02985.22 KXS18222.1 - 1.2e-13 50.1 27.0 0.065 13.5 0.1 10.8 11 0 0 11 11 11 4 HEAT repeat HEAT_2 PF13646.6 KXS18222.1 - 8.9e-06 26.0 13.8 0.0009 19.6 1.2 5.7 3 1 1 5 5 5 1 HEAT repeats ResIII PF04851.15 KXS18222.1 - 0.0039 17.2 0.0 0.0074 16.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF3385 PF11865.8 KXS18222.1 - 0.0064 16.4 0.1 0.017 15.0 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3385) CLASP_N PF12348.8 KXS18222.1 - 0.039 13.5 0.0 1.8 8.1 0.0 2.8 3 0 0 3 3 3 0 CLASP N terminal HEAT_EZ PF13513.6 KXS18222.1 - 0.5 10.9 23.8 6.7 7.3 0.1 7.6 6 1 1 7 7 7 0 HEAT-like repeat DUF1754 PF08555.10 KXS18223.1 - 2 9.3 5.4 17 6.3 0.1 2.5 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) DAO PF01266.24 KXS18224.1 - 5.5e-58 197.2 0.2 1.5e-37 130.0 0.1 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase Fer2_BFD PF04324.15 KXS18224.1 - 3.2e-14 53.0 3.1 9.8e-14 51.4 3.1 1.9 1 0 0 1 1 1 1 BFD-like [2Fe-2S] binding domain NAD_binding_8 PF13450.6 KXS18224.1 - 2e-05 24.8 0.8 5.5e-05 23.3 0.8 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KXS18224.1 - 0.00032 20.1 0.2 0.021 14.1 0.1 2.3 2 0 0 2 2 2 1 FAD binding domain TrkA_N PF02254.18 KXS18224.1 - 0.00044 20.5 0.3 0.0013 19.0 0.2 1.9 2 0 0 2 2 1 1 TrkA-N domain Thi4 PF01946.17 KXS18224.1 - 0.0032 16.7 0.1 0.0077 15.5 0.1 1.6 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 KXS18224.1 - 0.0051 15.9 0.3 0.015 14.3 0.1 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein 3HCDH_N PF02737.18 KXS18224.1 - 0.013 15.4 0.3 0.027 14.4 0.3 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 KXS18224.1 - 0.017 14.4 0.0 0.065 12.4 0.0 2.0 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.15 KXS18224.1 - 0.034 12.7 0.1 0.11 11.0 0.1 1.8 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) DAO_C PF16901.5 KXS18224.1 - 0.054 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 C-terminal domain of alpha-glycerophosphate oxidase Shikimate_DH PF01488.20 KXS18224.1 - 0.11 12.6 0.0 0.26 11.3 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 KXS18224.1 - 0.14 12.7 0.6 5.3 7.7 0.4 2.8 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KXS18224.1 - 0.15 11.3 0.2 0.28 10.5 0.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain SO_alpha_A3 PF17806.1 KXS18224.1 - 0.16 12.3 0.2 0.8 10.1 0.0 2.3 3 0 0 3 3 2 0 Sarcosine oxidase A3 domain Sacchrp_dh_NADP PF03435.18 KXS18224.1 - 0.22 11.8 2.3 0.72 10.1 0.3 2.5 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Thioredoxin PF00085.20 KXS18225.1 - 1.9e-07 31.0 0.1 1.1e-06 28.6 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin HTH_32 PF13565.6 KXS18226.1 - 3.1e-08 34.1 0.2 0.0044 17.6 0.0 2.5 2 0 0 2 2 2 2 Homeodomain-like domain HTH_23 PF13384.6 KXS18226.1 - 0.00041 20.1 1.4 0.028 14.2 0.0 3.0 3 0 0 3 3 3 1 Homeodomain-like domain CENP-B_N PF04218.13 KXS18226.1 - 0.00097 18.7 0.6 0.014 15.0 0.0 2.5 3 0 0 3 3 3 1 CENP-B N-terminal DNA-binding domain HTH_33 PF13592.6 KXS18226.1 - 0.0053 16.4 1.0 0.094 12.4 0.1 2.5 2 0 0 2 2 2 1 Winged helix-turn helix HTH_Tnp_1_2 PF13022.6 KXS18226.1 - 0.0074 16.4 0.2 0.049 13.8 0.2 2.1 1 1 0 1 1 1 1 Helix-turn-helix of insertion element transposase HTH_7 PF02796.15 KXS18226.1 - 0.011 15.8 0.5 0.1 12.7 0.1 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase HTH_11 PF08279.12 KXS18226.1 - 0.012 15.6 0.1 0.029 14.3 0.1 1.6 1 0 0 1 1 1 0 HTH domain HTH_36 PF13730.6 KXS18226.1 - 0.055 13.4 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Tnp_IS630 PF01710.16 KXS18226.1 - 0.062 13.4 0.0 0.31 11.1 0.0 2.0 2 0 0 2 2 2 0 Transposase HTH_28 PF13518.6 KXS18226.1 - 0.067 13.3 0.6 1.3 9.2 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain Phage_terminase PF10668.9 KXS18226.1 - 0.098 12.7 0.0 0.82 9.7 0.0 2.1 2 0 0 2 2 2 0 Phage terminase small subunit HTH_Tnp_Tc3_2 PF01498.18 KXS18226.1 - 0.14 12.4 0.5 0.65 10.3 0.1 2.1 2 0 0 2 2 2 0 Transposase CH PF00307.31 KXS18227.1 - 1.7e-10 41.0 0.0 3e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain RseA_C PF03873.13 KXS18227.1 - 5.5 7.3 12.4 5.3 7.4 0.2 4.1 4 0 0 4 4 4 0 Anti sigma-E protein RseA, C-terminal domain Guanylate_cyc PF00211.20 KXS18228.1 - 3.7e-05 23.4 0.0 0.054 13.1 0.0 2.1 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain Ysc84 PF04366.12 KXS18229.1 - 1.5e-41 141.1 1.1 2.9e-41 140.2 1.1 1.5 1 0 0 1 1 1 1 Las17-binding protein actin regulator SH3_1 PF00018.28 KXS18229.1 - 1.2e-12 47.2 0.1 2.2e-12 46.4 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KXS18229.1 - 8.7e-12 44.7 0.3 1.5e-11 44.0 0.3 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KXS18229.1 - 0.00048 19.7 0.7 0.0012 18.5 0.1 2.0 2 0 0 2 2 2 1 Variant SH3 domain Ras PF00071.22 KXS18230.1 - 1.4e-53 180.9 0.1 1.6e-53 180.7 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXS18230.1 - 1.3e-19 70.6 0.0 2.1e-19 69.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXS18230.1 - 9e-08 31.8 0.0 1.1e-07 31.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KXS18230.1 - 1.5e-05 24.9 0.0 0.035 14.0 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 KXS18230.1 - 0.0002 21.0 0.0 0.00089 18.8 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain TniB PF05621.11 KXS18230.1 - 0.054 12.9 0.0 11 5.4 0.0 2.5 2 1 0 2 2 2 0 Bacterial TniB protein MMR_HSR1 PF01926.23 KXS18230.1 - 0.093 12.8 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_25 PF13481.6 KXS18230.1 - 0.11 12.1 0.0 0.84 9.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain FMO-like PF00743.19 KXS18231.1 - 5.8e-21 74.5 1.1 1.7e-20 73.0 1.1 1.8 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KXS18231.1 - 1.3e-11 44.3 0.0 2.1e-06 27.2 0.0 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXS18231.1 - 1.5e-10 40.8 0.1 1.3e-06 27.8 0.0 3.1 3 0 0 3 3 3 3 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KXS18231.1 - 1.1e-08 35.2 0.1 4.1e-08 33.3 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KXS18231.1 - 4e-07 29.6 0.2 0.00022 20.6 0.0 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXS18231.1 - 0.00014 21.6 0.3 0.0033 17.1 0.2 2.5 2 1 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KXS18231.1 - 0.00018 21.5 0.0 0.051 13.6 0.0 3.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding GIDA PF01134.22 KXS18231.1 - 0.0041 16.3 0.1 0.13 11.3 0.0 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox PF00070.27 KXS18231.1 - 0.012 16.2 0.9 0.93 10.1 0.3 3.0 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KXS18231.1 - 0.11 11.5 0.1 7.8 5.4 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein Ank_3 PF13606.6 KXS18232.1 - 1.6e-06 28.0 0.0 0.00029 21.1 0.0 3.7 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.7 KXS18232.1 - 1.1e-05 25.9 0.0 2.6e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXS18232.1 - 0.00024 21.6 0.0 0.00093 19.7 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXS18232.1 - 0.0049 17.2 0.0 0.041 14.2 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 KXS18232.1 - 0.02 15.3 0.0 0.22 12.0 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeat SlyX PF04102.12 KXS18232.1 - 0.047 14.3 0.2 0.12 13.0 0.2 1.7 1 0 0 1 1 1 0 SlyX DUF5595 PF18077.1 KXS18232.1 - 0.31 11.2 2.6 0.66 10.1 2.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5595) PHD PF00628.29 KXS18234.1 - 1.5e-08 34.4 9.8 1.5e-08 34.4 9.8 2.2 3 0 0 3 3 3 1 PHD-finger zf-PHD-like PF15446.6 KXS18234.1 - 0.34 10.5 2.3 0.63 9.7 2.3 1.5 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain FYVE_2 PF02318.16 KXS18234.1 - 0.95 9.7 3.6 0.39 10.9 0.8 1.7 2 0 0 2 2 2 0 FYVE-type zinc finger PHD_4 PF16866.5 KXS18234.1 - 2.2 8.4 11.3 1.9 8.7 8.9 2.2 2 0 0 2 2 2 0 PHD-finger C1_1 PF00130.22 KXS18234.1 - 2.2 8.2 6.8 1.6 8.6 2.2 2.6 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DZR PF12773.7 KXS18234.1 - 7.6 6.6 9.8 5.8e+02 0.6 0.0 3.5 2 1 0 2 2 2 0 Double zinc ribbon Sigma70_ner PF04546.13 KXS18234.1 - 9 6.1 8.4 1.5 8.7 2.2 2.3 2 0 0 2 2 2 0 Sigma-70, non-essential region Skp1 PF01466.19 KXS18235.1 - 1.2e-28 98.9 0.7 2e-28 98.2 0.7 1.4 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 KXS18235.1 - 4.5e-20 71.6 0.2 1.3e-19 70.1 0.1 1.9 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain Myb_DNA-binding PF00249.31 KXS18235.1 - 0.044 14.0 0.5 7.7 6.8 0.0 2.5 2 0 0 2 2 2 0 Myb-like DNA-binding domain PX PF00787.24 KXS18236.1 - 3.3e-06 27.1 4.9 0.00019 21.4 4.9 2.4 1 1 0 1 1 1 1 PX domain CNH PF00780.22 KXS18237.1 - 5.1e-54 183.7 0.0 8.6e-54 183.0 0.0 1.2 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.20 KXS18237.1 - 6.3e-17 62.4 0.0 9.3e-17 61.8 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.21 KXS18237.1 - 1.2e-06 28.5 0.0 2.5e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH_5 PF15405.6 KXS18237.1 - 0.00025 21.1 0.0 0.022 14.9 0.0 2.4 1 1 1 2 2 2 2 Pleckstrin homology domain PH PF00169.29 KXS18237.1 - 0.056 13.9 0.0 0.12 12.9 0.0 1.5 1 0 0 1 1 1 0 PH domain HAD_2 PF13419.6 KXS18238.1 - 1.3e-10 41.6 0.0 3.2e-10 40.4 0.0 1.7 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KXS18238.1 - 6.1e-06 26.7 0.0 5.5e-05 23.5 0.0 2.3 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KXS18238.1 - 1.6e-05 24.9 0.0 5e-05 23.3 0.0 1.8 1 1 1 2 2 2 1 HAD-hyrolase-like VEGFR-2_TMD PF17988.1 KXS18240.1 - 4 7.0 6.6 8.9 5.8 6.6 1.6 1 0 0 1 1 1 0 VEGFR-2 Transmembrane domain Ribosomal_S27e PF01667.17 KXS18241.1 - 2.4e-26 91.2 2.9 3.6e-26 90.6 2.9 1.3 1 0 0 1 1 1 1 Ribosomal protein S27 Utp21 PF04192.12 KXS18242.1 - 0.064 12.8 0.0 0.45 10.0 0.0 2.0 2 0 0 2 2 2 0 Utp21 specific WD40 associated putative domain Gpr1_Fun34_YaaH PF01184.19 KXS18243.1 - 2.3e-08 33.9 0.1 3.2e-08 33.4 0.1 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Sulfate_transp PF00916.20 KXS18244.1 - 2.7e-92 309.5 15.0 4.4e-92 308.8 15.0 1.3 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KXS18244.1 - 2.6e-14 52.8 0.1 5.3e-14 51.8 0.1 1.5 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 KXS18244.1 - 0.01 16.2 3.5 0.01 16.2 3.5 2.6 2 1 0 2 2 2 0 Molybdate transporter of MFS superfamily Ribosomal_L2_C PF03947.18 KXS18246.1 - 4.5e-40 136.7 0.7 9.1e-40 135.8 0.7 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 KXS18246.1 - 3.3e-17 62.2 0.0 7.7e-17 61.0 0.0 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain zf-C3HC4_3 PF13920.6 KXS18247.1 - 3.7e-07 29.9 4.9 5.6e-07 29.3 4.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXS18247.1 - 2.2e-06 27.4 3.9 3.7e-06 26.7 3.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXS18247.1 - 1.6e-05 24.7 3.2 0.00012 21.8 0.9 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXS18247.1 - 4.6e-05 23.7 4.1 0.0001 22.6 4.2 1.5 1 1 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KXS18247.1 - 5.1e-05 23.2 1.8 0.00024 21.1 0.6 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 KXS18247.1 - 0.0009 19.1 5.5 0.0014 18.5 5.5 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KXS18247.1 - 0.0013 18.9 5.6 0.0023 18.1 5.6 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING DUF4682 PF15733.5 KXS18247.1 - 0.52 10.9 3.1 15 6.2 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4682) Prok-RING_4 PF14447.6 KXS18247.1 - 0.62 10.0 4.8 1.3 9.0 4.8 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 KXS18247.1 - 0.84 10.0 4.3 1.7 9.0 4.3 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C2H2_4 PF13894.6 KXS18248.1 - 1.4e-05 25.5 6.8 0.064 14.1 0.8 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KXS18248.1 - 7.6e-05 23.0 11.3 0.0082 16.5 1.0 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KXS18248.1 - 0.00034 20.9 5.3 0.0031 17.9 0.6 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_2 PF12756.7 KXS18248.1 - 0.008 16.5 0.7 0.58 10.5 0.1 2.4 1 1 1 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-H2C2_5 PF13909.6 KXS18248.1 - 0.066 13.0 3.1 4.2 7.2 0.3 2.7 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-met PF12874.7 KXS18248.1 - 0.075 13.5 0.7 2.2 8.8 0.0 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type CpXC PF14353.6 KXS18248.1 - 0.077 13.0 0.2 0.15 12.1 0.2 1.4 1 0 0 1 1 1 0 CpXC protein zf-C2H2_jaz PF12171.8 KXS18248.1 - 0.094 13.0 0.2 0.54 10.6 0.0 2.2 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KXS18248.1 - 0.21 11.6 5.9 3.8 7.6 2.0 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger GST_C PF00043.25 KXS18249.1 - 2.2e-07 31.0 0.0 4.2e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KXS18249.1 - 2.6e-07 30.8 0.0 1.2e-06 28.7 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KXS18249.1 - 4.4e-07 30.2 0.0 2.7e-06 27.7 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KXS18249.1 - 2.8e-06 27.2 0.2 8.9e-06 25.6 0.1 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KXS18249.1 - 0.011 15.9 0.1 0.03 14.5 0.0 1.8 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KXS18249.1 - 0.016 15.5 0.0 0.042 14.2 0.0 1.7 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Glyco_hydr_30_2 PF14587.6 KXS18250.1 - 2.2e-15 57.1 0.1 4.3e-13 49.6 0.0 2.7 2 1 0 2 2 2 2 O-Glycosyl hydrolase family 30 AMP-binding PF00501.28 KXS18251.1 - 3.8e-23 81.8 0.4 1.5e-22 79.8 0.4 1.8 1 1 0 1 1 1 1 AMP-binding enzyme Na_Ca_ex PF01699.24 KXS18252.1 - 8.2e-19 68.0 42.6 1.3e-11 44.6 15.4 3.5 3 0 0 3 3 3 2 Sodium/calcium exchanger protein YccF PF03733.13 KXS18252.1 - 8.3e-06 26.4 21.1 8.3e-06 26.4 21.1 5.4 5 1 0 5 5 5 1 Inner membrane component domain RPEL PF02755.15 KXS18253.1 - 2.8e-10 39.6 8.3 0.011 15.4 0.2 5.2 5 0 0 5 5 5 4 RPEL repeat UPF0240 PF06784.11 KXS18253.1 - 0.029 14.4 0.4 0.24 11.4 0.1 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0240) Kisspeptin PF15152.6 KXS18253.1 - 0.039 14.7 0.7 0.091 13.6 0.2 1.9 1 1 1 2 2 2 0 Kisspeptin SET PF00856.28 KXS18254.1 - 4.8e-11 43.3 0.0 2.1e-10 41.3 0.0 2.1 2 1 0 2 2 2 1 SET domain GTP_EFTU PF00009.27 KXS18255.1 - 3.8e-18 65.7 0.1 8.4e-18 64.6 0.0 1.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 KXS18255.1 - 4.1e-09 36.7 0.9 2.1e-08 34.4 0.2 2.5 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.17 KXS18255.1 - 5.1e-05 23.5 0.0 0.00016 22.0 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain PduV-EutP PF10662.9 KXS18255.1 - 0.00059 19.6 0.1 0.11 12.2 0.1 3.1 2 1 1 3 3 3 1 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 KXS18255.1 - 0.0048 17.0 0.0 0.012 15.7 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 KXS18255.1 - 0.12 12.9 0.0 0.41 11.2 0.0 1.8 2 0 0 2 2 2 0 ABC transporter CKS PF01111.19 KXS18256.1 - 3.1e-27 94.6 0.8 4.2e-27 94.2 0.8 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit Ribosomal_L22 PF00237.19 KXS18257.1 - 2.1e-22 79.3 0.0 3.6e-22 78.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Stonin2_N PF12016.8 KXS18257.1 - 0.0079 15.7 0.6 0.0079 15.7 0.6 1.5 2 0 0 2 2 2 1 Stonin 2 7tm_2 PF00002.24 KXS18258.1 - 0.081 12.2 0.4 0.12 11.6 0.4 1.3 1 0 0 1 1 1 0 7 transmembrane receptor (Secretin family) RAP1 PF07218.11 KXS18258.1 - 6.2 5.0 5.2 8.2 4.6 5.2 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) ubiquitin PF00240.23 KXS18259.1 - 2.3e-14 52.9 0.5 4.1e-14 52.1 0.5 1.5 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 KXS18259.1 - 0.0036 17.7 0.1 0.0062 17.0 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 KXS18259.1 - 0.014 15.3 0.0 0.026 14.4 0.0 1.5 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain GldM_N PF12081.8 KXS18259.1 - 0.077 13.1 1.0 0.11 12.5 1.0 1.3 1 0 0 1 1 1 0 GldM N-terminal domain Receptor_IA-2 PF11548.8 KXS18259.1 - 0.094 12.7 0.1 0.25 11.4 0.1 1.7 1 0 0 1 1 1 0 Protein-tyrosine phosphatase receptor IA-2 ANTAR PF03861.14 KXS18259.1 - 0.15 12.0 0.1 0.29 11.0 0.1 1.4 1 0 0 1 1 1 0 ANTAR domain START PF01852.19 KXS18260.1 - 4.7e-14 52.3 0.3 7.9e-14 51.6 0.3 1.3 1 0 0 1 1 1 1 START domain SH3_9 PF14604.6 KXS18263.1 - 7.9e-08 32.0 0.0 1.7e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXS18263.1 - 1.8e-06 27.5 0.0 3.7e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KXS18263.1 - 0.00044 19.9 0.0 0.0011 18.6 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain GAS PF13851.6 KXS18263.1 - 0.068 12.5 3.2 0.099 12.0 3.2 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Acetyltransf_3 PF13302.7 KXS18264.1 - 2.5e-09 37.9 0.0 4e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXS18264.1 - 0.00033 20.9 0.0 0.0005 20.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Ion_trans PF00520.31 KXS18265.1 - 3.6e-21 75.5 8.7 5.6e-21 74.9 8.7 1.2 1 0 0 1 1 1 1 Ion transport protein GPHH PF16905.5 KXS18265.1 - 0.087 12.6 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 Voltage-dependent L-type calcium channel, IQ-associated PKD_channel PF08016.12 KXS18265.1 - 0.099 11.3 10.2 0.33 9.6 10.2 1.8 1 1 0 1 1 1 0 Polycystin cation channel IQ PF00612.27 KXS18265.1 - 0.17 11.8 2.1 0.47 10.4 2.1 1.8 1 0 0 1 1 1 0 IQ calmodulin-binding motif Ion_trans PF00520.31 KXS18266.1 - 4.7e-51 173.4 10.6 2.4e-34 118.6 9.1 2.1 2 0 0 2 2 2 2 Ion transport protein GATA PF00320.27 KXS18267.1 - 2.3e-11 43.1 4.1 4.3e-11 42.2 4.1 1.4 1 0 0 1 1 1 1 GATA zinc finger ArfGap PF01412.18 KXS18267.1 - 0.083 13.0 0.2 0.16 12.0 0.2 1.4 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf DZR PF12773.7 KXS18267.1 - 0.17 11.9 0.4 0.76 9.8 0.4 1.8 1 1 1 2 2 2 0 Double zinc ribbon Zn-ribbon_8 PF09723.10 KXS18267.1 - 0.47 10.6 1.6 1.3 9.2 0.5 2.1 2 0 0 2 2 2 0 Zinc ribbon domain FAD_binding_1 PF00667.20 KXS18268.1 - 7e-33 114.1 0.0 1e-32 113.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KXS18268.1 - 5e-28 98.1 0.0 8.2e-28 97.4 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 KXS18268.1 - 5.1e-10 40.0 0.0 8.7e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 KXS18268.1 - 0.042 14.0 0.0 0.082 13.0 0.0 1.4 1 0 0 1 1 1 0 Ferric reductase NAD binding domain Flavodoxin_5 PF12724.7 KXS18268.1 - 0.13 12.5 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 Flavodoxin domain Drf_FH1 PF06346.12 KXS18268.1 - 5 6.8 10.2 0.26 11.0 3.5 2.1 2 0 0 2 2 2 0 Formin Homology Region 1 DUF4187 PF13821.6 KXS18269.1 - 3.2e-19 68.5 1.0 5.8e-19 67.6 1.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.23 KXS18269.1 - 5.1e-06 26.3 6.3 3.2e-05 23.7 3.3 2.4 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 KXS18269.1 - 0.006 16.6 2.1 0.058 13.5 0.7 2.6 2 0 0 2 2 2 1 G-patch domain zf-C2HE PF16278.5 KXS18269.1 - 0.19 12.2 0.5 4 8.0 0.0 2.8 3 0 0 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger Glyco_hydro_16 PF00722.21 KXS18270.1 - 9.5e-28 96.8 1.2 1.7e-27 96.0 1.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 EphA2_TM PF14575.6 KXS18270.1 - 0.03 15.2 0.0 2.5 9.1 0.0 2.4 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain stn_TNFRSF12A PF12191.8 KXS18270.1 - 0.093 13.0 0.1 2.4 8.4 0.0 2.4 2 0 0 2 2 2 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Phage_holin_3_6 PF07332.11 KXS18270.1 - 0.36 10.9 4.6 1.1 9.3 2.8 2.1 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III MAPEG PF01124.18 KXS18272.1 - 1.5e-12 47.5 2.4 1.7e-12 47.4 2.4 1.2 1 0 0 1 1 1 1 MAPEG family 2TM PF13239.6 KXS18272.1 - 0.085 13.2 0.1 0.085 13.2 0.1 2.0 2 0 0 2 2 2 0 2TM domain LRR_6 PF13516.6 KXS18273.1 - 2.3e-11 42.8 0.0 0.0087 16.0 0.0 3.5 3 0 0 3 3 3 3 Leucine Rich repeat LRR_4 PF12799.7 KXS18273.1 - 0.15 12.5 0.0 32 5.1 0.1 3.1 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) Usp PF00582.26 KXS18274.1 - 1.5e-15 58.0 0.0 1.2e-14 55.0 0.0 2.0 1 1 0 1 1 1 1 Universal stress protein family DUF601 PF04642.12 KXS18274.1 - 0.025 14.1 0.5 0.044 13.3 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF601 Hydrolase_4 PF12146.8 KXS18276.1 - 1.8e-50 171.5 0.0 2.1e-50 171.2 0.0 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KXS18276.1 - 5.8e-10 40.2 0.2 7.3e-10 39.8 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXS18276.1 - 4e-09 36.5 0.4 6.9e-08 32.4 0.4 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Lipase_3 PF01764.25 KXS18276.1 - 0.00043 20.2 0.0 0.0011 18.8 0.0 1.9 1 0 0 1 1 1 1 Lipase (class 3) Thioesterase PF00975.20 KXS18276.1 - 0.0076 16.4 0.0 0.012 15.7 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_3 PF07859.13 KXS18276.1 - 0.058 13.2 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KXS18276.1 - 0.063 12.7 0.5 2.3 7.6 0.5 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family PGAP1 PF07819.13 KXS18276.1 - 0.19 11.4 0.0 0.43 10.3 0.0 1.5 2 0 0 2 2 2 0 PGAP1-like protein Fer4 PF00037.27 KXS18277.1 - 6.1e-14 51.2 16.2 1.7e-08 33.9 4.5 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 KXS18277.1 - 3.2e-12 46.8 9.3 5.1e-12 46.2 9.3 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 KXS18277.1 - 6.5e-10 39.8 4.9 4.2e-05 24.4 0.1 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 KXS18277.1 - 2.3e-09 37.2 3.9 0.0006 19.9 0.5 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 KXS18277.1 - 1.9e-08 34.3 9.2 3e-08 33.7 9.2 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 KXS18277.1 - 5e-08 32.9 21.2 7.9e-06 25.9 12.2 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 KXS18277.1 - 9.3e-08 32.4 17.7 5.4e-05 23.5 10.5 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 KXS18277.1 - 1.3e-06 28.1 12.5 0.0027 17.7 2.0 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 KXS18277.1 - 5.5e-06 26.5 10.0 0.00031 21.0 1.1 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.7 KXS18277.1 - 6.3e-06 26.0 17.2 0.0066 16.5 4.8 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 KXS18277.1 - 0.00021 21.7 10.2 0.017 15.6 11.9 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_13 PF13370.6 KXS18277.1 - 0.0037 17.8 14.1 0.32 11.6 3.6 2.9 3 0 0 3 3 3 2 4Fe-4S single cluster domain of Ferredoxin I Fer4_18 PF13746.6 KXS18277.1 - 0.048 13.9 8.4 1.3 9.2 1.3 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain c-SKI_SMAD_bind PF08782.10 KXS18277.1 - 0.1 12.9 5.9 3.5 7.9 0.6 2.3 1 1 1 2 2 2 0 c-SKI Smad4 binding domain Fer4_3 PF12798.7 KXS18277.1 - 0.14 13.1 15.5 0.34 12.0 4.1 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_22 PF17179.4 KXS18277.1 - 0.7 10.8 11.4 2.7 8.9 1.8 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain ETF_QO PF05187.13 KXS18277.1 - 1.6 8.9 5.1 3.6 7.8 1.8 2.2 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_15 PF13459.6 KXS18277.1 - 3.3 8.5 12.8 5.6 7.8 4.2 3.0 2 1 0 2 2 2 0 4Fe-4S single cluster domain HSP70 PF00012.20 KXS18278.1 - 9.5e-268 889.3 14.9 1.1e-267 889.1 14.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KXS18278.1 - 2.5e-14 52.9 4.2 4.7e-12 45.4 2.2 2.6 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 KXS18278.1 - 4.6e-05 23.2 0.1 0.00011 22.0 0.1 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 KXS18278.1 - 0.0023 18.3 6.8 1 9.8 0.3 3.9 3 1 0 3 3 3 2 Cell division protein FtsA DMRL_synthase PF00885.19 KXS18278.1 - 0.063 13.1 0.4 0.19 11.6 0.1 1.9 2 0 0 2 2 2 0 6,7-dimethyl-8-ribityllumazine synthase Helicase_C PF00271.31 KXS18279.1 - 0.00049 20.4 0.0 0.00079 19.7 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Pyr_redox_2 PF07992.14 KXS18280.1 - 3e-37 128.4 1.7 3.8e-37 128.1 1.7 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.26 KXS18280.1 - 1.3e-10 41.0 0.0 2.9e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox PF00070.27 KXS18280.1 - 2.5e-06 28.0 3.4 0.0076 16.8 0.1 3.4 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KXS18280.1 - 7.2e-05 21.8 0.3 0.031 13.1 0.0 2.1 2 0 0 2 2 2 2 Tryptophan halogenase Pyr_redox_3 PF13738.6 KXS18280.1 - 0.03 13.6 0.9 1.4 8.1 0.0 2.9 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 KXS18280.1 - 0.037 14.4 0.0 0.082 13.4 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding NAD_binding_9 PF13454.6 KXS18280.1 - 0.31 11.0 5.3 0.95 9.4 0.1 3.5 4 0 0 4 4 4 0 FAD-NAD(P)-binding Rad10 PF03834.14 KXS18281.1 - 4.2e-38 129.9 0.0 5.6e-38 129.5 0.0 1.2 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.6 KXS18281.1 - 1.8e-09 38.0 0.1 2.9e-09 37.4 0.1 1.3 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_2 PF12826.7 KXS18281.1 - 1.4e-06 28.3 0.0 2.4e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH PF00633.23 KXS18281.1 - 1.3e-05 24.8 0.2 2.8e-05 23.7 0.2 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_3 PF12836.7 KXS18281.1 - 0.12 12.7 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 Helix-hairpin-helix motif OPT PF03169.15 KXS18282.1 - 4.5e-86 289.8 38.3 5.7e-86 289.5 38.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein ECH_1 PF00378.20 KXS18283.1 - 3.5e-51 173.9 0.1 4.1e-51 173.7 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXS18283.1 - 9.7e-26 91.0 0.2 1.2e-25 90.7 0.2 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase IMPa_helical PF18642.1 KXS18284.1 - 7e-36 123.0 0.4 1.8e-35 121.7 0.1 1.8 2 0 0 2 2 2 1 Immunomodulating metalloprotease helical domain Peptidase_M60 PF13402.6 KXS18284.1 - 1.9e-12 47.3 0.3 7.4e-12 45.3 0.3 2.0 1 1 0 1 1 1 1 Peptidase M60, enhancin and enhancin-like IMPa_N_2 PF18650.1 KXS18284.1 - 4.8e-11 42.3 2.5 1.2e-10 41.0 0.0 2.8 2 1 0 2 2 2 1 Immunomodulating metalloprotease N-terminal domain M60-like_N PF17291.2 KXS18284.1 - 0.0019 18.1 0.1 0.0049 16.7 0.1 1.7 1 0 0 1 1 1 1 N-terminal domain of M60-like peptidases MTP18 PF10558.9 KXS18285.1 - 2.7e-19 69.8 2.5 1.9e-10 41.0 0.2 2.1 1 1 1 2 2 2 2 Mitochondrial 18 KDa protein (MTP18) PLAC8 PF04749.17 KXS18286.1 - 4.7e-09 37.1 0.7 5.9e-09 36.8 0.7 1.1 1 0 0 1 1 1 1 PLAC8 family UQ_con PF00179.26 KXS18287.1 - 3.2e-38 130.5 0.1 3.9e-38 130.3 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme F-actin_cap_A PF01267.17 KXS18288.1 - 8.1e-86 287.7 0.0 9.2e-86 287.6 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit LIM PF00412.22 KXS18289.1 - 1.7e-48 162.6 43.3 2.3e-12 46.9 2.9 5.3 5 1 0 5 5 5 5 LIM domain RecO_C PF02565.15 KXS18289.1 - 2.9 7.6 19.4 5.9 6.7 0.8 4.6 3 1 1 4 4 4 0 Recombination protein O C terminal HECT PF00632.25 KXS18290.1 - 1.4e-75 254.7 0.0 2.6e-75 253.8 0.0 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Arm PF00514.23 KXS18290.1 - 0.091 12.8 0.2 37 4.6 0.0 3.6 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Pro_isomerase PF00160.21 KXS18291.1 - 4.7e-45 153.7 0.1 5.2e-45 153.5 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD FAD_binding_1 PF00667.20 KXS18292.1 - 8.4e-50 169.4 0.0 1.2e-49 168.9 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 KXS18292.1 - 1.1e-12 48.6 0.0 2.2e-12 47.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KXS18292.1 - 0.0058 17.0 0.0 0.013 15.9 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain IF4E PF01652.18 KXS18294.1 - 2.8e-51 173.5 0.0 3.3e-51 173.2 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E ATP_synth_reg PF14960.6 KXS18295.1 - 0.035 13.6 1.1 0.15 11.6 0.8 2.2 2 1 1 3 3 3 0 ATP synthase regulation TrbC PF04956.13 KXS18295.1 - 0.092 13.0 0.4 0.14 12.4 0.4 1.4 1 0 0 1 1 1 0 TrbC/VIRB2 family UbiA PF01040.18 KXS18296.1 - 9.5e-52 175.8 23.5 1.3e-51 175.3 23.5 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family TrbC PF04956.13 KXS18296.1 - 0.024 14.8 2.5 0.07 13.3 0.0 2.6 3 0 0 3 3 3 0 TrbC/VIRB2 family zf-RING_5 PF14634.6 KXS18297.1 - 8.4e-06 25.6 7.2 8.4e-06 25.6 7.2 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 KXS18297.1 - 0.00012 22.3 7.0 0.00012 22.3 7.0 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 KXS18297.1 - 0.00057 19.7 14.6 0.0014 18.4 10.3 2.7 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXS18297.1 - 0.0068 16.2 6.2 0.0068 16.2 6.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXS18297.1 - 0.012 15.7 6.3 0.012 15.7 6.3 1.7 2 0 0 2 2 1 0 RING-type zinc-finger zf-WRNIP1_ubi PF18279.1 KXS18297.1 - 0.027 15.1 1.3 0.51 11.1 0.0 2.9 2 0 0 2 2 2 0 Werner helicase-interacting protein 1 ubiquitin-binding domain zf-ANAPC11 PF12861.7 KXS18297.1 - 0.031 14.3 1.7 0.031 14.3 1.7 1.7 2 0 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 KXS18297.1 - 0.038 13.8 10.0 0.047 13.6 6.2 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) SAP PF02037.27 KXS18297.1 - 0.068 12.9 0.0 0.18 11.6 0.0 1.8 1 0 0 1 1 1 0 SAP domain TRAF6_Z2 PF18048.1 KXS18297.1 - 0.16 12.1 0.9 16 5.7 0.0 2.5 2 0 0 2 2 2 0 TNF receptor-associated factor 6 zinc finger 2 zf-rbx1 PF12678.7 KXS18297.1 - 0.24 11.7 9.6 0.034 14.4 3.7 2.3 2 0 0 2 2 2 0 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 KXS18297.1 - 0.67 9.9 12.9 23 4.9 0.1 2.9 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 KXS18297.1 - 0.73 9.8 6.5 0.09 12.7 2.3 1.7 2 0 0 2 2 1 0 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.6 KXS18297.1 - 1.4 9.2 11.9 0.47 10.7 6.6 2.3 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 KXS18297.1 - 2 8.6 8.9 0.54 10.4 5.4 1.8 2 0 0 2 2 2 0 zinc RING finger of MSL2 zf-RING_4 PF14570.6 KXS18297.1 - 2.3 8.1 10.4 2.9 7.8 1.9 3.0 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain CpXC PF14353.6 KXS18297.1 - 2.7 8.0 7.0 6.5 6.8 2.8 2.8 2 1 0 2 2 2 0 CpXC protein DUF1295 PF06966.12 KXS18299.1 - 1.3e-48 165.6 1.0 1.6e-48 165.3 1.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.16 KXS18299.1 - 7.3e-06 26.0 0.2 1.4e-05 25.1 0.2 1.5 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase ICMT PF04140.14 KXS18299.1 - 0.00096 19.5 0.5 0.0046 17.3 0.1 2.4 2 1 1 3 3 3 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KXS18299.1 - 0.0023 18.3 0.2 0.0023 18.3 0.2 2.5 2 1 1 3 3 3 1 Phospholipid methyltransferase Tup_N PF08581.10 KXS18300.1 - 0.012 15.9 0.8 0.012 15.9 0.8 22.7 20 8 7 28 28 28 0 Tup N-terminal Surfac_D-trimer PF09006.11 KXS18300.1 - 0.81 9.6 2.6 61 3.6 0.0 4.3 3 0 0 3 3 3 0 Lung surfactant protein D coiled-coil trimerisation Pyr_redox_2 PF07992.14 KXS18301.1 - 2.1e-14 53.4 0.4 3.1e-14 52.9 0.4 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXS18301.1 - 1.6e-05 24.4 0.6 0.00062 19.1 0.2 2.0 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXS18301.1 - 2.7e-05 23.5 0.9 0.015 14.5 0.0 2.7 1 1 2 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.14 KXS18301.1 - 3.9e-05 22.7 0.1 0.0001 21.3 0.0 1.7 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox PF00070.27 KXS18301.1 - 0.00063 20.2 0.2 0.00063 20.2 0.2 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXS18301.1 - 0.002 17.8 0.0 0.002 17.8 0.0 3.0 1 1 2 3 3 3 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KXS18301.1 - 0.0048 16.9 2.8 0.19 11.7 0.0 2.9 3 0 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_7 PF13241.6 KXS18301.1 - 0.0059 17.0 0.5 0.94 9.9 0.0 2.4 2 1 0 2 2 2 1 Putative NAD(P)-binding GIDA PF01134.22 KXS18301.1 - 0.01 14.9 0.1 0.54 9.3 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 KXS18301.1 - 0.052 12.8 0.3 0.82 8.9 0.0 2.1 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_8 PF13450.6 KXS18301.1 - 0.083 13.1 0.0 0.083 13.1 0.0 2.2 2 0 0 2 2 1 0 NAD(P)-binding Rossmann-like domain zf-C2H2 PF00096.26 KXS18302.1 - 8.7e-08 32.2 13.8 0.00011 22.5 2.8 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXS18302.1 - 1.7e-05 25.3 13.8 0.0064 17.2 2.3 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KXS18302.1 - 0.00028 21.2 12.4 0.0059 17.0 4.0 3.6 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KXS18302.1 - 0.006 16.8 2.3 0.3 11.4 0.2 3.0 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KXS18302.1 - 0.15 12.5 2.1 7 7.2 0.8 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 KXS18302.1 - 0.66 9.8 10.5 0.092 12.5 4.3 2.2 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 KXS18302.1 - 3.2 7.9 9.8 6.4 6.9 0.4 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger Trimer_CC PF08954.11 KXS18303.1 - 0.016 14.8 1.5 0.024 14.2 1.5 1.3 1 0 0 1 1 1 0 Trimerisation motif FliW PF02623.15 KXS18303.1 - 0.18 11.8 0.0 0.23 11.4 0.0 1.3 1 1 0 1 1 1 0 FliW protein VASt PF16016.5 KXS18304.1 - 6e-17 62.5 0.0 9.1e-17 61.9 0.0 1.3 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 KXS18304.1 - 3.7e-08 33.2 0.1 6.8e-08 32.4 0.1 1.4 1 0 0 1 1 1 1 GRAM domain Tmemb_14 PF03647.13 KXS18305.1 - 1.6e-23 83.2 8.3 2e-23 82.9 8.3 1.1 1 0 0 1 1 1 1 Transmembrane proteins 14C Trypsin PF00089.26 KXS18306.1 - 3.3e-18 66.3 0.2 3.8e-18 66.1 0.2 1.1 1 0 0 1 1 1 1 Trypsin Ecl1 PF12855.7 KXS18307.1 - 4.1e-05 24.8 11.8 4.1e-05 24.8 11.8 2.7 2 1 0 2 2 2 1 ECL1/2/3 zinc binding proteins BCMA-Tall_bind PF09257.10 KXS18307.1 - 0.4 10.8 3.7 0.3 11.2 0.8 2.1 2 0 0 2 2 2 0 BCMA, TALL-1 binding ATG7_N PF16420.5 KXS18308.1 - 1.4e-76 258.0 0.0 1.8e-76 257.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus ThiF PF00899.21 KXS18308.1 - 3.4e-38 131.4 0.0 5.2e-38 130.8 0.0 1.2 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 KXS18308.1 - 0.13 12.3 0.0 1.4 9.0 0.0 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NOT2_3_5 PF04153.18 KXS18309.1 - 1.1e-20 74.1 0.0 1.4e-20 73.7 0.0 1.1 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Sugar_tr PF00083.24 KXS18310.1 - 6.7e-121 404.3 22.5 7.8e-121 404.1 22.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXS18310.1 - 2.1e-20 73.0 41.6 6e-17 61.6 16.3 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2530 PF10745.9 KXS18310.1 - 5.5 7.3 10.3 0.6 10.4 1.6 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2530) Spc24 PF08286.11 KXS18311.1 - 6.4e-13 48.9 0.0 1.5e-12 47.7 0.0 1.6 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 Lzipper-MIP1 PF14389.6 KXS18311.1 - 0.023 15.0 0.1 0.052 13.9 0.1 1.7 1 1 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 LPP PF04728.13 KXS18311.1 - 0.056 13.8 0.5 0.49 10.8 0.5 2.3 1 1 0 1 1 1 0 Lipoprotein leucine-zipper TolA_bind_tri PF16331.5 KXS18311.1 - 0.075 13.1 0.2 0.18 11.9 0.2 1.6 1 0 0 1 1 1 0 TolA binding protein trimerisation PI3K_P85_iSH2 PF16454.5 KXS18311.1 - 0.1 12.2 0.1 0.14 11.8 0.1 1.3 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain CLZ PF16526.5 KXS18311.1 - 0.12 12.8 1.3 0.17 12.2 0.2 1.9 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels TPR_MLP1_2 PF07926.12 KXS18311.1 - 0.24 11.4 4.9 1.5 8.9 0.5 2.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein FUSC PF04632.12 KXS18311.1 - 0.24 9.9 1.7 0.27 9.7 1.7 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family MAD PF05557.13 KXS18312.1 - 1.6e-31 109.4 50.5 2.8e-18 65.7 0.0 3.6 2 1 0 2 2 2 2 Mitotic checkpoint protein HALZ PF02183.18 KXS18312.1 - 2.2e-06 27.7 27.8 1 9.6 0.3 8.4 7 1 1 8 8 8 4 Homeobox associated leucine zipper Pox_A_type_inc PF04508.12 KXS18312.1 - 0.035 14.0 24.0 1.7 8.6 0.0 7.4 6 1 1 7 7 7 0 Viral A-type inclusion protein repeat ZapB PF06005.12 KXS18312.1 - 0.036 14.5 0.0 0.036 14.5 0.0 9.7 6 4 1 7 7 7 0 Cell division protein ZapB Lzipper-MIP1 PF14389.6 KXS18312.1 - 0.042 14.1 0.2 0.042 14.1 0.2 7.7 7 3 2 9 9 9 0 Leucine-zipper of ternary complex factor MIP1 TSC22 PF01166.18 KXS18312.1 - 0.25 11.7 22.3 3.1 8.2 0.5 6.6 7 1 1 8 8 8 0 TSC-22/dip/bun family DUF5082 PF16888.5 KXS18312.1 - 4.6 7.5 30.1 0.42 10.9 0.6 6.0 4 2 0 5 5 5 0 Domain of unknown function (DUF5082) Fungal_TACC PF12709.7 KXS18312.1 - 9.9 6.7 29.8 15 6.1 0.2 8.4 6 2 5 11 11 11 0 Fungal Transforming acidic coiled-coil (TACC) proteins TBP PF00352.21 KXS18314.1 - 2.3e-67 222.9 0.1 2.3e-33 114.0 0.1 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 KXS18314.1 - 4.9e-06 26.6 0.0 0.027 14.6 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) DUF4295 PF14128.6 KXS18314.1 - 0.048 13.5 0.2 0.33 10.8 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4295) SMC_N PF02463.19 KXS18315.1 - 1.5e-61 207.7 15.8 2.9e-61 206.7 15.8 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KXS18315.1 - 4.2e-28 98.0 0.0 1.9e-27 95.9 0.0 2.3 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 KXS18315.1 - 4.3e-15 56.8 21.4 4.3e-15 56.8 21.4 7.4 2 2 3 5 5 5 1 AAA domain AAA_21 PF13304.6 KXS18315.1 - 9.7e-15 55.1 9.4 1.8e-09 37.9 0.9 3.9 4 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KXS18315.1 - 4.5e-14 52.9 19.4 3.1e-12 46.9 4.0 4.3 2 2 1 4 4 4 2 AAA ATPase domain Spc7 PF08317.11 KXS18315.1 - 0.00059 18.8 14.5 0.00059 18.8 14.5 6.4 2 2 4 6 6 6 2 Spc7 kinetochore protein AAA_29 PF13555.6 KXS18315.1 - 0.014 15.1 0.0 0.03 14.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF2019 PF09450.10 KXS18315.1 - 0.089 12.8 5.2 1 9.4 0.4 3.4 2 0 0 2 2 2 0 Domain of unknown function (DUF2019) APG6_N PF17675.1 KXS18315.1 - 2.4 8.7 120.4 0.3 11.6 19.5 7.6 3 2 4 7 7 7 0 Apg6 coiled-coil region Phytochelatin PF05023.14 KXS18316.1 - 7.8e-75 250.7 0.0 9.4e-75 250.5 0.0 1.1 1 0 0 1 1 1 1 Phytochelatin synthase Peptidase_C39_2 PF13529.6 KXS18316.1 - 0.18 12.3 0.0 7.1 7.2 0.0 2.3 2 0 0 2 2 2 0 Peptidase_C39 like family Nop PF01798.18 KXS18317.1 - 5.8e-88 294.2 0.0 7.8e-88 293.8 0.0 1.2 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 KXS18317.1 - 1.1e-20 73.8 0.3 2.7e-20 72.5 0.3 1.8 1 0 0 1 1 1 1 NOP5NT (NUC127) domain RHH_6 PF16762.5 KXS18317.1 - 0.041 14.5 0.5 21 5.8 0.0 3.5 3 0 0 3 3 3 0 Ribbon-helix-helix domain HU-CCDC81_euk_2 PF18289.1 KXS18318.1 - 5.3e-10 39.3 0.0 1.4e-09 38.0 0.0 1.8 1 0 0 1 1 1 1 CCDC81 eukaryotic HU domain 2 HU-CCDC81_euk_1 PF14908.6 KXS18318.1 - 0.0011 19.1 0.0 0.0027 17.8 0.0 1.6 1 0 0 1 1 1 1 CCDC81 eukaryotic HU domain 1 HU-HIG PF18291.1 KXS18318.1 - 0.0019 18.3 0.0 0.79 9.8 0.0 2.6 2 0 0 2 2 2 2 HU domain fused to wHTH, Ig, or Glycine-rich motif Sod_Fe_C PF02777.18 KXS18319.1 - 7.4e-41 138.5 0.2 1.3e-40 137.7 0.2 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 KXS18319.1 - 2.4e-25 88.8 0.0 4.7e-25 87.9 0.0 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain KASH_CCD PF14662.6 KXS18320.1 - 0.05 13.4 2.3 0.2 11.5 0.4 2.4 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH DASH_Hsk3 PF08227.11 KXS18320.1 - 0.24 11.8 2.8 0.28 11.6 0.3 2.5 2 0 0 2 2 2 0 DASH complex subunit Hsk3 like DUF4510 PF14971.6 KXS18320.1 - 0.32 11.3 8.5 0.65 10.3 1.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4510) DivIC PF04977.15 KXS18320.1 - 1.8 8.4 4.5 0.99 9.2 1.5 2.1 2 0 0 2 2 2 0 Septum formation initiator Condensation PF00668.20 KXS18322.1 - 0.0077 15.0 0.0 0.21 10.2 0.0 2.0 2 0 0 2 2 2 2 Condensation domain SOUL PF04832.12 KXS18323.1 - 0.0017 18.6 0.0 0.0028 17.8 0.0 1.3 1 0 0 1 1 1 1 SOUL heme-binding protein CwsA PF10814.8 KXS18324.1 - 0.048 13.8 1.6 0.048 13.8 1.6 1.6 1 1 0 1 1 1 0 Cell wall synthesis protein CwsA RskA PF10099.9 KXS18324.1 - 0.084 13.2 9.4 0.13 12.6 9.4 1.3 1 1 0 1 1 1 0 Anti-sigma-K factor rskA SLATT_1 PF18181.1 KXS18324.1 - 0.73 9.8 5.5 0.58 10.1 1.0 2.0 1 1 2 3 3 3 0 SMODS and SLOG-associating 2TM effector domain 1 MFS_1 PF07690.16 KXS18325.1 - 1.1e-21 77.1 15.0 2e-21 76.3 15.0 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily zf-RING_2 PF13639.6 KXS18326.1 - 7.7e-13 48.6 9.2 9.1e-13 48.3 6.3 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 KXS18326.1 - 1.9e-09 37.2 6.0 1.9e-09 37.2 6.0 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KXS18326.1 - 1.4e-08 34.9 6.2 3.1e-08 33.8 6.2 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 KXS18326.1 - 7.5e-07 28.8 2.9 7.5e-07 28.8 2.9 1.9 2 0 0 2 2 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 KXS18326.1 - 4.2e-06 26.5 5.3 4.2e-06 26.5 5.3 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KXS18326.1 - 0.0001 22.1 3.1 0.0001 22.1 3.1 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXS18326.1 - 0.00014 21.8 2.2 0.00014 21.8 2.2 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 KXS18326.1 - 0.0067 16.4 3.9 0.0067 16.4 3.9 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 KXS18326.1 - 0.018 15.1 5.9 0.055 13.5 5.9 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 KXS18326.1 - 0.11 12.7 6.2 0.3 11.3 6.2 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 KXS18326.1 - 0.13 11.9 7.4 0.3 10.8 7.4 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type PHD PF00628.29 KXS18326.1 - 2 8.4 5.2 3.6 7.6 5.2 1.4 1 0 0 1 1 1 0 PHD-finger RINGv PF12906.7 KXS18326.1 - 2.8 8.1 8.7 5.5 7.2 8.7 1.5 1 0 0 1 1 1 0 RING-variant domain zf-RING-like PF08746.11 KXS18326.1 - 3.9 7.9 6.4 7.3 7.0 6.4 1.4 1 0 0 1 1 1 0 RING-like domain Prok-RING_4 PF14447.6 KXS18326.1 - 5.8 6.9 12.4 0.055 13.3 3.9 1.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 PALP PF00291.25 KXS18327.1 - 4.3e-42 144.5 0.3 5.6e-42 144.2 0.3 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Sel1 PF08238.12 KXS18328.1 - 4e-41 138.5 19.5 9.8e-09 35.6 0.4 5.5 5 0 0 5 5 5 5 Sel1 repeat Pkinase_Tyr PF07714.17 KXS18328.1 - 1.4e-30 106.5 0.0 4.5e-21 75.3 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXS18328.1 - 1e-18 67.7 0.0 7.8e-17 61.5 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KXS18328.1 - 8.5e-05 22.0 0.0 0.00017 21.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family TPR_16 PF13432.6 KXS18328.1 - 2.5 8.8 10.5 28 5.4 0.4 3.7 2 2 2 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 KXS18328.1 - 2.8 8.3 6.0 36 4.8 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat F-box PF00646.33 KXS18329.1 - 3e-05 23.8 0.0 9e-05 22.2 0.0 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KXS18329.1 - 3.4e-05 23.7 0.1 8.1e-05 22.4 0.1 1.7 1 0 0 1 1 1 1 F-box-like DZR PF12773.7 KXS18330.1 - 0.00022 21.2 8.1 0.002 18.1 5.5 2.3 2 0 0 2 2 2 1 Double zinc ribbon zf-ribbon_3 PF13248.6 KXS18330.1 - 0.01 15.2 8.0 0.13 11.7 0.7 2.8 3 0 0 3 3 3 0 zinc-ribbon domain HAUS2 PF15003.6 KXS18330.1 - 0.046 13.4 0.1 0.23 11.2 0.1 2.0 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 2 Cation_efflux PF01545.21 KXS18331.1 - 1e-25 90.7 6.1 1.3e-25 90.3 6.1 1.1 1 0 0 1 1 1 1 Cation efflux family FeoB_associated PF12669.7 KXS18331.1 - 0.21 12.0 1.3 20 5.7 0.2 2.4 2 0 0 2 2 2 0 FeoB-associated Cys-rich membrane protein DUF2880 PF11082.8 KXS18333.1 - 0.074 13.4 0.0 0.22 11.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2880) LSM PF01423.22 KXS18334.1 - 4.5e-19 67.9 0.0 5.8e-19 67.5 0.0 1.2 1 0 0 1 1 1 1 LSM domain Ribosomal_S8 PF00410.19 KXS18335.1 - 4.1e-18 65.6 0.0 2.7e-17 62.9 0.0 1.9 1 1 0 1 1 1 1 Ribosomal protein S8 2_5_RNA_ligase2 PF13563.6 KXS18337.1 - 0.019 14.9 0.0 0.17 11.8 0.0 2.1 2 0 0 2 2 2 0 2'-5' RNA ligase superfamily Ribosomal_L5 PF00281.19 KXS18338.1 - 2.6e-21 75.7 0.0 9.6e-21 73.9 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L5 Ribosomal_L5_C PF00673.21 KXS18338.1 - 3.9e-21 75.0 0.0 6.2e-21 74.4 0.0 1.4 1 0 0 1 1 1 1 ribosomal L5P family C-terminus BRCT_2 PF16589.5 KXS18340.1 - 0.00019 21.8 0.0 0.00032 21.0 0.0 1.4 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain DNA_ligase_IV PF11411.8 KXS18340.1 - 0.002 18.2 0.1 0.0037 17.4 0.1 1.5 1 0 0 1 1 1 1 DNA ligase IV PTCB-BRCT PF12738.7 KXS18340.1 - 0.003 17.5 0.1 0.0082 16.1 0.0 1.7 2 0 0 2 2 2 1 twin BRCT domain LIG3_BRCT PF16759.5 KXS18340.1 - 0.0034 17.6 0.0 0.0066 16.7 0.0 1.5 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain BRCT PF00533.26 KXS18340.1 - 0.029 14.7 0.0 0.074 13.4 0.0 1.7 1 1 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain DNA_ligase_A_M PF01068.21 KXS18341.1 - 1.6e-50 171.6 0.0 2.5e-50 170.9 0.0 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KXS18341.1 - 2e-33 116.2 0.0 2.9e-33 115.6 0.0 1.3 1 0 0 1 1 1 1 DNA ligase N terminus RNA_ligase PF09414.10 KXS18341.1 - 2.9e-12 47.2 0.0 5.4e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 RNA ligase DNA_ligase_A_C PF04679.15 KXS18341.1 - 2.4e-09 37.7 0.0 7.3e-09 36.1 0.0 1.8 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region mRNA_cap_enzyme PF01331.19 KXS18341.1 - 0.0015 18.4 0.0 0.15 11.9 0.0 2.7 2 0 0 2 2 2 1 mRNA capping enzyme, catalytic domain MukF_C PF17193.4 KXS18341.1 - 0.0091 16.2 0.1 0.026 14.6 0.1 1.8 1 1 0 1 1 1 1 MukF C-terminal domain Y_phosphatase2 PF03162.13 KXS18342.1 - 8.2e-56 188.1 0.0 9.4e-56 187.9 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 KXS18342.1 - 0.0001 22.4 0.0 0.00038 20.5 0.0 1.8 1 1 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 KXS18342.1 - 0.00029 20.7 0.0 0.00035 20.4 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KXS18342.1 - 0.016 14.8 0.0 0.019 14.5 0.0 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase B9-C2 PF07162.11 KXS18343.1 - 6.8e-30 104.5 0.0 1.6e-29 103.2 0.0 1.7 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein Peptidase_C54 PF03416.19 KXS18344.1 - 3.5e-82 275.9 0.0 4.3e-82 275.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 SET PF00856.28 KXS18345.1 - 6.5e-23 81.9 0.1 2.3e-22 80.2 0.1 1.8 1 1 0 1 1 1 1 SET domain N-SET PF11764.8 KXS18345.1 - 0.00012 22.3 0.1 0.0014 18.8 0.1 2.1 1 1 0 1 1 1 1 COMPASS (Complex proteins associated with Set1p) component N Clathrin PF00637.20 KXS18347.1 - 3e-208 682.1 44.2 2.2e-33 115.1 2.7 7.9 8 0 0 8 8 8 7 Region in Clathrin and VPS Clathrin_propel PF01394.20 KXS18347.1 - 5.5e-43 143.2 0.1 2.8e-08 33.7 0.0 6.6 6 0 0 6 6 6 6 Clathrin propeller repeat Clathrin_H_link PF13838.6 KXS18347.1 - 1e-29 102.2 0.3 4e-29 100.3 0.0 2.2 2 0 0 2 2 2 1 Clathrin-H-link Clathrin-link PF09268.10 KXS18347.1 - 2.6e-09 36.3 1.3 1e-08 34.3 1.3 2.2 1 0 0 1 1 1 1 Clathrin, heavy-chain linker TPR_2 PF07719.17 KXS18347.1 - 4.4e-05 23.3 1.2 1.1 9.5 0.0 5.7 5 0 0 5 5 5 1 Tetratricopeptide repeat Coatomer_WDAD PF04053.14 KXS18347.1 - 7.7e-05 21.9 2.3 0.027 13.5 0.0 3.7 4 0 0 4 4 4 2 Coatomer WD associated region TPR_1 PF00515.28 KXS18347.1 - 0.00098 18.9 6.4 0.5 10.3 0.0 5.0 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 KXS18347.1 - 0.0025 17.7 2.2 9.4 6.5 0.0 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 KXS18347.1 - 0.0071 16.5 2.1 0.75 10.2 0.0 4.9 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 KXS18347.1 - 0.056 14.3 10.3 38 5.5 0.1 7.3 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_12 PF13424.6 KXS18347.1 - 0.14 12.5 4.8 28 5.1 0.1 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat Pet191_N PF10203.9 KXS18348.1 - 0.0041 17.4 4.9 0.035 14.4 3.4 2.6 2 1 1 3 3 3 2 Cytochrome c oxidase assembly protein PET191 ubiquitin PF00240.23 KXS18351.1 - 0.001 18.8 0.2 0.019 14.7 0.0 2.2 2 0 0 2 2 2 1 Ubiquitin family Ubiquitin_2 PF14560.6 KXS18351.1 - 0.026 15.0 0.0 0.056 13.9 0.0 1.4 1 1 0 1 1 1 0 Ubiquitin-like domain MFS_1 PF07690.16 KXS18352.1 - 2.9e-12 46.2 28.0 4.9e-12 45.4 27.9 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Peptidase_M16_C PF05193.21 KXS18353.1 - 5.1e-14 52.7 0.0 4.4e-09 36.6 0.0 2.9 2 1 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KXS18353.1 - 1.7e-07 31.4 0.1 6.3e-07 29.5 0.0 1.7 1 1 0 2 2 2 1 Insulinase (Peptidase family M16) DNA_pol_phi PF04931.13 KXS18353.1 - 0.88 7.6 13.6 1.7 6.7 13.6 1.4 1 0 0 1 1 1 0 DNA polymerase phi ADH_zinc_N PF00107.26 KXS18354.1 - 2.3e-19 69.7 0.1 3.9e-19 68.9 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXS18354.1 - 5.8e-07 29.4 0.0 1.4e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KXS18354.1 - 0.035 15.2 0.0 0.065 14.3 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase RhoGAP PF00620.27 KXS18356.1 - 3.4e-22 78.9 0.0 6e-22 78.1 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain PikAIV_N PF18605.1 KXS18356.1 - 0.014 14.9 3.6 0.036 13.7 3.6 1.7 1 0 0 1 1 1 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain Fe-S_biosyn PF01521.20 KXS18357.1 - 1.7e-16 60.4 0.0 2.7e-16 59.7 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Pkinase PF00069.25 KXS18360.1 - 3.6e-27 95.4 0.0 9e-14 51.5 0.0 3.1 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 KXS18360.1 - 1.6e-06 27.7 0.0 0.026 13.8 0.0 2.7 3 0 0 3 3 3 2 Protein tyrosine kinase PP2C PF00481.21 KXS18361.1 - 3.2e-57 194.1 0.0 4.3e-57 193.7 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 KXS18361.1 - 0.0027 17.4 0.0 0.0069 16.0 0.0 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C Mod_r PF07200.13 KXS18362.1 - 0.14 12.3 0.4 0.3 11.2 0.4 1.5 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein TctA PF01970.16 KXS18363.1 - 0.0004 19.2 0.9 0.00051 18.9 0.7 1.3 1 1 0 1 1 1 1 Tripartite tricarboxylate transporter TctA family SUR7 PF06687.12 KXS18363.1 - 0.0047 16.6 6.1 0.037 13.7 6.1 2.1 1 1 0 1 1 1 1 SUR7/PalI family DUF4537 PF15057.6 KXS18364.1 - 0.00057 19.9 0.0 0.0012 18.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) LBR_tudor PF09465.10 KXS18364.1 - 0.015 15.1 0.1 0.028 14.2 0.1 1.4 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain Tudor_3 PF18115.1 KXS18364.1 - 0.019 14.8 0.3 0.034 14.0 0.3 1.4 1 0 0 1 1 1 0 DNA repair protein Crb2 Tudor domain PWWP PF00855.17 KXS18365.1 - 9.6e-06 25.9 0.2 1.8e-05 25.0 0.2 1.5 1 0 0 1 1 1 1 PWWP domain F-box-like PF12937.7 KXS18366.1 - 2.8e-08 33.5 0.2 6.2e-08 32.4 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXS18366.1 - 1.7e-05 24.6 1.1 3.6e-05 23.5 1.1 1.5 1 0 0 1 1 1 1 F-box domain WD40 PF00400.32 KXS18366.1 - 0.0013 19.5 9.7 0.44 11.5 0.4 4.9 4 0 0 4 4 4 2 WD domain, G-beta repeat Pkinase PF00069.25 KXS18367.1 - 1.2e-59 201.8 0.0 1.6e-59 201.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS18367.1 - 1.4e-20 73.7 0.0 2.1e-20 73.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXS18367.1 - 1.5e-05 25.0 0.1 4.1e-05 23.6 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXS18367.1 - 0.02 13.7 0.1 0.045 12.5 0.0 1.5 2 0 0 2 2 2 0 Fungal protein kinase Kinase-like PF14531.6 KXS18367.1 - 0.089 12.1 0.0 12 5.1 0.0 2.1 2 0 0 2 2 2 0 Kinase-like Kdo PF06293.14 KXS18367.1 - 0.11 11.8 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family LIDHydrolase PF10230.9 KXS18368.1 - 7.5e-48 163.4 0.1 9.1e-48 163.1 0.1 1.1 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Hydrolase_4 PF12146.8 KXS18368.1 - 3e-07 29.9 0.1 4.8e-07 29.3 0.1 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KXS18368.1 - 0.00031 20.5 1.8 0.016 14.9 1.8 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.20 KXS18368.1 - 0.00041 20.5 0.0 0.00083 19.5 0.0 1.5 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_3 PF07859.13 KXS18368.1 - 0.0018 18.2 0.0 0.0026 17.7 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Ank_3 PF13606.6 KXS18369.1 - 3e-06 27.1 0.1 0.019 15.5 0.0 4.0 4 0 0 4 4 4 1 Ankyrin repeat Ank_2 PF12796.7 KXS18369.1 - 1.1e-05 26.0 0.3 0.027 15.1 0.0 3.4 3 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXS18369.1 - 3e-05 24.5 0.0 0.08 13.6 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KXS18369.1 - 4.7e-05 23.6 0.0 0.39 11.3 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 KXS18369.1 - 0.00029 21.1 0.1 0.042 14.2 0.1 3.1 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Endonuclease_NS PF01223.23 KXS18371.1 - 1e-30 107.2 0.0 1.4e-30 106.8 0.0 1.2 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease PQQ PF01011.21 KXS18371.1 - 0.026 14.5 0.0 0.066 13.2 0.0 1.7 1 0 0 1 1 1 0 PQQ enzyme repeat Ceramidase PF05875.12 KXS18372.1 - 0.0021 17.6 7.8 0.0021 17.6 7.8 2.4 2 1 0 3 3 3 1 Ceramidase SLATT_fungal PF18142.1 KXS18372.1 - 0.13 12.2 3.6 0.32 11.0 3.6 1.6 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain MFS_1 PF07690.16 KXS18373.1 - 3e-29 102.0 49.8 1.2e-23 83.6 30.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KXS18373.1 - 1e-12 47.4 13.7 5.3e-07 28.6 2.7 2.2 2 0 0 2 2 2 2 MFS/sugar transport protein Sugar_tr PF00083.24 KXS18373.1 - 0.00028 19.9 6.4 0.00028 19.9 6.4 2.3 2 2 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.7 KXS18373.1 - 0.00036 19.5 0.3 0.00036 19.5 0.3 2.2 2 0 0 2 2 2 1 MFS_1 like family OATP PF03137.20 KXS18373.1 - 2.4 6.3 10.3 0.064 11.5 0.6 2.5 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Ank_3 PF13606.6 KXS18374.1 - 0.00029 21.0 0.0 0.0012 19.1 0.0 2.1 1 0 0 1 1 1 1 Ankyrin repeat Ank_2 PF12796.7 KXS18374.1 - 0.0071 16.9 0.0 0.017 15.7 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KXS18374.1 - 0.0077 16.6 0.1 0.021 15.3 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeat Lipase_chap PF03280.14 KXS18374.1 - 0.2 11.6 0.9 0.37 10.7 0.9 1.3 1 0 0 1 1 1 0 Proteobacterial lipase chaperone protein DUF2353 PF09789.9 KXS18374.1 - 0.27 10.6 0.0 0.41 10.0 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) RINGv PF12906.7 KXS18376.1 - 2.7e-09 37.0 4.2 2e-08 34.3 4.2 2.2 1 1 0 1 1 1 1 RING-variant domain zinc_ribbon_4 PF13717.6 KXS18376.1 - 0.39 10.7 2.6 0.28 11.1 0.2 1.9 2 0 0 2 2 2 0 zinc-ribbon domain zf-RING_2 PF13639.6 KXS18376.1 - 3.6 8.0 7.6 16 5.9 7.6 2.0 1 1 0 1 1 1 0 Ring finger domain Methyltransf_16 PF10294.9 KXS18377.1 - 5.8e-28 97.8 0.2 8e-28 97.3 0.2 1.1 1 0 0 1 1 1 1 Lysine methyltransferase GidB PF02527.15 KXS18377.1 - 0.00039 19.8 0.1 0.00095 18.5 0.1 1.8 2 1 0 2 2 2 1 rRNA small subunit methyltransferase G MTS PF05175.14 KXS18377.1 - 0.00041 19.9 0.0 0.0006 19.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Met_10 PF02475.16 KXS18377.1 - 0.063 13.0 0.0 0.086 12.6 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Trp_syntA PF00290.20 KXS18379.1 - 5.3e-92 307.3 0.2 8.2e-92 306.7 0.2 1.2 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.25 KXS18379.1 - 3e-45 154.9 0.4 6.6e-45 153.8 0.4 1.5 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme His_biosynth PF00977.21 KXS18379.1 - 0.00097 18.7 0.2 0.0023 17.4 0.2 1.6 1 0 0 1 1 1 1 Histidine biosynthesis protein Prim-Pol PF09250.11 KXS18379.1 - 0.058 13.8 0.0 1.3 9.4 0.0 2.3 2 0 0 2 2 2 0 Bifunctional DNA primase/polymerase, N-terminal MFS_1 PF07690.16 KXS18380.1 - 1.3e-17 63.8 35.6 2.2e-06 26.9 0.3 4.7 3 1 1 4 4 4 4 Major Facilitator Superfamily LacY_symp PF01306.19 KXS18380.1 - 6.9 5.3 13.8 0.054 12.3 0.9 2.8 3 0 0 3 3 3 0 LacY proton/sugar symporter Clr2_transil PF16761.5 KXS18381.1 - 7.4e-10 39.5 6.5 1.3e-09 38.7 0.8 3.1 3 1 0 3 3 3 1 Transcription-silencing protein, cryptic loci regulator Clr2 GCP_C_terminal PF04130.13 KXS18383.1 - 3e-70 237.1 1.7 3.1e-70 237.1 0.4 1.7 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 KXS18383.1 - 6.8e-69 232.8 0.0 1.1e-68 232.1 0.0 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal MSA-2c PF12238.8 KXS18383.1 - 0.15 12.0 3.1 0.32 11.0 3.1 1.4 1 0 0 1 1 1 0 Merozoite surface antigen 2c RasGAP PF00616.19 KXS18385.1 - 3.9e-22 79.0 0.0 3e-12 46.7 0.0 2.5 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase C2 PF00168.30 KXS18385.1 - 1.6e-15 57.3 0.0 1.1e-09 38.5 0.0 2.4 2 0 0 2 2 2 2 C2 domain C1_1 PF00130.22 KXS18385.1 - 5.5e-10 39.0 4.4 5.5e-10 39.0 4.4 1.7 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD PF00628.29 KXS18385.1 - 0.0079 16.1 4.3 0.021 14.7 4.3 1.7 1 0 0 1 1 1 1 PHD-finger DUF1077 PF06417.12 KXS18386.1 - 1.1e-41 141.5 1.8 1.5e-41 141.1 1.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) tRNA-synt_1g PF09334.11 KXS18387.1 - 2.7e-153 510.4 0.0 3.7e-153 509.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 KXS18387.1 - 6.1e-10 38.0 0.2 3.1e-06 25.7 0.0 2.8 2 1 1 3 3 3 2 tRNA synthetases class I (I, L, M and V) WHEP-TRS PF00458.20 KXS18387.1 - 5.8e-09 36.0 1.7 1.4e-08 34.8 1.7 1.7 1 0 0 1 1 1 1 WHEP-TRS domain tRNA-synt_1e PF01406.19 KXS18387.1 - 2.9e-05 23.6 0.0 0.0001 21.7 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain Mannitol_dh PF01232.23 KXS18387.1 - 0.22 11.7 0.2 0.54 10.4 0.1 1.7 2 0 0 2 2 2 0 Mannitol dehydrogenase Rossmann domain SMC_Nse1 PF07574.13 KXS18388.1 - 4.2e-29 101.8 0.0 7.3e-28 97.8 0.0 2.1 1 1 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.11 KXS18388.1 - 1.2e-05 25.6 7.6 1.2e-05 25.6 7.6 1.8 2 0 0 2 2 2 1 RING-like domain C1_1 PF00130.22 KXS18388.1 - 0.019 14.9 1.3 0.019 14.9 1.3 2.2 3 1 1 4 4 4 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF313 PF03754.13 KXS18388.1 - 0.057 13.6 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF313) zf-ribbon_3 PF13248.6 KXS18388.1 - 0.43 10.1 5.4 1.4 8.4 0.3 2.6 2 0 0 2 2 2 0 zinc-ribbon domain Zn_Tnp_IS91 PF14319.6 KXS18388.1 - 3.2 7.9 10.2 1.7 8.7 4.4 2.6 2 1 1 3 3 3 0 Transposase zinc-binding domain C1_2 PF03107.16 KXS18388.1 - 4 7.8 9.2 1.6 9.1 0.6 3.5 4 0 0 4 4 4 0 C1 domain zf-C4_Topoisom PF01396.19 KXS18388.1 - 6.8 6.6 6.6 24 4.8 0.3 2.6 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger Voltage_CLC PF00654.20 KXS18389.1 - 9e-90 301.5 33.0 9e-90 301.5 33.0 2.0 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 KXS18389.1 - 3.6e-06 27.3 0.0 0.0019 18.6 0.0 2.5 2 0 0 2 2 2 2 CBS domain TAT_signal PF10518.9 KXS18389.1 - 2.2 8.3 6.8 33 4.5 0.1 3.2 2 0 0 2 2 2 0 TAT (twin-arginine translocation) pathway signal sequence SH3_9 PF14604.6 KXS18390.1 - 2e-05 24.3 0.0 3.4e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain CcmD PF04995.14 KXS18390.1 - 0.22 11.6 2.0 0.37 10.9 2.0 1.3 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) HS1_rep PF02218.15 KXS18391.1 - 2e-12 47.2 3.5 2e-12 47.2 3.5 2.1 2 0 0 2 2 2 1 Repeat in HS1/Cortactin TMEM210 PF15195.6 KXS18391.1 - 0.096 13.1 0.0 0.14 12.6 0.0 1.2 1 0 0 1 1 1 0 TMEM210 family Ank_2 PF12796.7 KXS18392.1 - 0.0012 19.4 0.0 0.031 14.8 0.1 2.6 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXS18392.1 - 0.0015 18.9 0.9 0.56 10.9 0.2 3.8 4 0 0 4 4 4 1 Ankyrin repeat Ank PF00023.30 KXS18392.1 - 0.0039 17.6 4.4 0.1 13.1 0.4 3.6 3 2 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 KXS18392.1 - 0.027 14.8 0.4 0.099 13.0 0.1 2.1 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Methyltransf_21 PF05050.12 KXS18394.1 - 1.4e-12 48.0 0.0 2.2e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain SH3_9 PF14604.6 KXS18395.1 - 1.4e-11 44.0 0.0 2.5e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXS18395.1 - 4.1e-09 35.9 0.1 7e-09 35.2 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KXS18395.1 - 5.4e-06 26.0 0.0 1.3e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Chitin_synth_1 PF01644.17 KXS18396.1 - 1.9e-57 193.8 0.0 3.1e-57 193.1 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.15 KXS18396.1 - 5.1e-25 88.1 8.0 3.4e-23 82.1 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Chitin_synth_1N PF08407.11 KXS18396.1 - 6.2e-18 64.5 0.0 1.4e-17 63.4 0.0 1.7 1 0 0 1 1 1 1 Chitin synthase N-terminal Glyco_trans_2_3 PF13632.6 KXS18396.1 - 0.0021 18.0 19.3 0.0021 18.0 19.3 2.9 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KXS18396.1 - 0.023 14.6 0.0 0.043 13.7 0.0 1.5 1 1 0 1 1 1 0 Glycosyltransferase like family 2 PAP2 PF01569.21 KXS18397.1 - 1.6e-15 57.1 3.6 1.6e-15 57.1 3.6 1.4 2 0 0 2 2 2 1 PAP2 superfamily MerC PF03203.14 KXS18397.1 - 3.6 8.1 12.7 4.4e+02 1.3 12.7 2.6 1 1 0 1 1 1 0 MerC mercury resistance protein SPX PF03105.19 KXS18398.1 - 6.1 6.7 11.3 13 5.5 11.3 1.5 1 0 0 1 1 1 0 SPX domain PRIMA1 PF16101.5 KXS18398.1 - 9.2 6.3 21.8 0.51 10.4 7.5 3.9 4 0 0 4 4 4 0 Proline-rich membrane anchor 1 HLH PF00010.26 KXS18399.1 - 6.6e-10 38.8 0.2 1.6e-09 37.6 0.2 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Macoilin PF09726.9 KXS18399.1 - 0.002 16.8 1.1 0.0025 16.5 1.1 1.1 1 0 0 1 1 1 1 Macoilin family DivIC PF04977.15 KXS18399.1 - 0.0098 15.6 3.0 0.02 14.7 2.3 1.9 1 1 0 1 1 1 1 Septum formation initiator TolA_bind_tri PF16331.5 KXS18399.1 - 1.3 9.2 11.8 0.19 11.8 3.9 2.9 2 1 1 3 3 3 0 TolA binding protein trimerisation Spc7 PF08317.11 KXS18399.1 - 4.4 6.1 9.3 0.78 8.6 4.3 1.8 2 0 0 2 2 2 0 Spc7 kinetochore protein GGACT PF06094.12 KXS18400.1 - 4.3e-18 66.1 0.1 6.8e-18 65.4 0.1 1.3 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like KAAG1 PF15354.6 KXS18400.1 - 0.068 13.7 0.2 0.068 13.7 0.2 1.8 2 0 0 2 2 2 0 Kidney-associated antigen 1 Zn_clus PF00172.18 KXS18401.1 - 0.00029 20.9 11.2 0.0004 20.4 11.2 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain KLRAQ PF10205.9 KXS18401.1 - 0.14 12.5 0.1 0.21 11.8 0.1 1.3 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein Acetyltransf_1 PF00583.25 KXS18402.1 - 6.4e-10 39.3 0.0 1.5e-09 38.1 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXS18402.1 - 8e-08 32.3 0.0 1.8e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXS18402.1 - 1.3e-05 25.5 0.0 2.6e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXS18402.1 - 8.1e-05 22.5 0.0 0.00014 21.8 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 KXS18402.1 - 0.0019 18.3 0.0 0.004 17.3 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 KXS18402.1 - 0.0024 17.9 0.0 0.0045 17.1 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Iso_dh PF00180.20 KXS18403.1 - 1e-78 264.9 0.0 1.2e-78 264.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Yippee-Mis18 PF03226.14 KXS18404.1 - 5.9e-16 58.6 0.9 6.8e-16 58.4 0.9 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RNA_pol_N PF01194.17 KXS18404.1 - 0.092 13.1 2.2 0.41 11.0 0.1 2.3 1 1 1 2 2 2 0 RNA polymerases N / 8 kDa subunit Kp4 PF09044.10 KXS18404.1 - 0.43 10.7 3.1 0.46 10.6 0.3 2.1 1 1 1 2 2 2 0 Kp4 adh_short PF00106.25 KXS18405.1 - 3.1e-32 111.6 0.1 4e-32 111.3 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXS18405.1 - 3.4e-26 92.3 0.1 5e-26 91.7 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXS18405.1 - 9.6e-06 25.6 0.1 1.8e-05 24.7 0.1 1.4 1 1 0 1 1 1 1 KR domain Shikimate_DH PF01488.20 KXS18405.1 - 0.0076 16.3 0.0 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DUF4473 PF14747.6 KXS18405.1 - 0.18 12.4 0.3 2.8 8.6 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4473) Polysacc_synt_2 PF02719.15 KXS18405.1 - 0.19 10.8 0.0 0.26 10.4 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein ECH_2 PF16113.5 KXS18406.1 - 1.4e-116 389.6 0.0 2e-116 389.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 KXS18406.1 - 6.7e-29 100.9 0.0 1.1e-28 100.2 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase DnaJ PF00226.31 KXS18408.1 - 9.8e-26 89.7 7.0 1.3e-25 89.3 3.8 2.5 2 0 0 2 2 2 1 DnaJ domain TPR_2 PF07719.17 KXS18408.1 - 1.1e-14 53.2 3.4 0.004 17.2 0.0 7.6 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_11 PF13414.6 KXS18408.1 - 4.2e-11 42.4 1.1 5.9e-05 22.7 0.0 5.2 5 0 0 5 5 5 2 TPR repeat TPR_1 PF00515.28 KXS18408.1 - 2.4e-09 36.6 6.8 0.011 15.5 0.1 6.3 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 KXS18408.1 - 5.3e-06 26.8 3.4 11 6.6 0.2 5.9 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 KXS18408.1 - 0.00012 22.3 2.5 2.8 8.3 0.0 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 KXS18408.1 - 0.00062 19.6 0.7 2.2 8.5 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 KXS18408.1 - 0.0013 19.4 4.3 65 4.7 0.2 6.2 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_9 PF13371.6 KXS18408.1 - 0.049 13.8 6.7 1.7 8.8 0.5 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KXS18408.1 - 0.1 12.8 2.1 14 5.9 0.2 4.1 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 KXS18408.1 - 1.6 9.2 7.1 1.6 9.2 0.1 4.3 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 KXS18408.1 - 9.1 7.0 12.6 45 4.8 0.1 5.7 6 1 0 6 6 6 0 Tetratricopeptide repeat THUMP PF02926.17 KXS18409.1 - 2.3e-13 50.5 0.0 5.3e-13 49.3 0.0 1.6 1 0 0 1 1 1 1 THUMP domain DHHW PF14286.6 KXS18409.1 - 0.2 10.9 0.5 0.35 10.1 0.0 1.5 2 0 0 2 2 2 0 DHHW protein PAXIP1_C PF15364.6 KXS18409.1 - 0.21 11.9 2.0 2.8 8.2 0.1 2.2 2 0 0 2 2 2 0 PAXIP1-associated-protein-1 C term PTIP binding protein ADIP PF11559.8 KXS18410.1 - 0.015 15.4 0.8 0.024 14.7 0.8 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Spc7 PF08317.11 KXS18410.1 - 0.082 11.8 0.1 0.12 11.3 0.1 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Med21 PF11221.8 KXS18410.1 - 0.16 12.2 0.2 0.32 11.3 0.2 1.6 1 0 0 1 1 1 0 Subunit 21 of Mediator complex APG6_N PF17675.1 KXS18410.1 - 0.23 12.0 0.1 0.37 11.3 0.1 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region CENP-F_leu_zip PF10473.9 KXS18410.1 - 0.24 11.4 0.3 0.36 10.8 0.3 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spectrin PF00435.21 KXS18410.1 - 0.24 11.9 0.2 0.38 11.3 0.2 1.3 1 0 0 1 1 1 0 Spectrin repeat SlyX PF04102.12 KXS18410.1 - 1.2 9.8 3.1 18 6.0 3.1 2.5 1 1 0 1 1 1 0 SlyX Herpes_UL25 PF01499.16 KXS18412.1 - 0.047 12.2 0.2 0.047 12.2 0.2 1.6 2 0 0 2 2 2 0 Herpesvirus UL25 family SlyX PF04102.12 KXS18412.1 - 3.4 8.4 6.8 1.3 9.7 0.1 2.8 3 0 0 3 3 3 0 SlyX RCC1 PF00415.18 KXS18413.1 - 6.8e-11 42.6 1.2 1.2e-10 41.9 0.2 1.9 2 1 0 2 2 2 1 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KXS18413.1 - 1.1e-06 28.3 3.4 1.1e-05 25.0 0.8 2.8 3 0 0 3 3 3 1 Regulator of chromosome condensation (RCC1) repeat Glyco_tran_28_C PF04101.16 KXS18414.1 - 6.7e-20 71.7 0.1 1.8e-19 70.3 0.1 1.6 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain SHIPPO-rpt PF07004.12 KXS18416.1 - 7.5e-12 45.6 79.7 0.027 15.4 1.3 10.9 10 0 0 10 10 10 8 Sperm-tail PG-rich repeat 2OG-FeII_Oxy PF03171.20 KXS18419.1 - 2.6e-18 66.4 0.0 4.7e-18 65.5 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 KXS18419.1 - 5.7e-18 65.8 0.0 9.1e-18 65.1 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Lyase_1 PF00206.20 KXS18420.1 - 1e-111 373.3 0.0 1.5e-111 372.7 0.0 1.3 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 KXS18420.1 - 4.5e-26 91.0 0.0 1.1e-25 89.8 0.0 1.7 1 0 0 1 1 1 1 Fumarase C C-terminus 4HBT PF03061.22 KXS18421.1 - 1.8e-11 44.2 0.0 2.8e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily Viral_cys_rich PF08008.12 KXS18421.1 - 0.066 13.3 0.0 0.19 11.8 0.0 1.6 2 0 0 2 2 2 0 Viral cysteine rich Collagen_mid PF15984.5 KXS18422.1 - 0.4 10.4 62.2 0.063 13.0 13.5 4.0 1 1 2 3 3 3 0 Bacterial collagen, middle region NUDIX PF00293.28 KXS18423.1 - 8.7e-18 64.6 0.0 1.7e-17 63.7 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.11 KXS18423.1 - 3.9e-11 43.5 0.0 1.1e-10 42.1 0.0 1.8 2 0 0 2 2 2 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.11 KXS18423.1 - 2.6e-06 27.0 1.2 5.1e-06 26.0 1.2 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain SBP PF03110.14 KXS18423.1 - 0.12 12.7 0.4 0.28 11.5 0.4 1.5 1 0 0 1 1 1 0 SBP domain DNA_ligase_ZBD PF03119.16 KXS18423.1 - 0.22 11.6 2.5 1.7 8.7 0.9 2.4 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain CHCH PF06747.13 KXS18424.1 - 0.00036 20.6 0.8 0.0009 19.3 0.8 1.8 1 0 0 1 1 1 1 CHCH domain CBFD_NFYB_HMF PF00808.23 KXS18425.1 - 8.9e-06 25.9 0.0 1.8e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone AAA PF00004.29 KXS18426.1 - 3.5e-40 137.5 0.0 5.7e-40 136.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KXS18426.1 - 2.5e-08 33.6 0.0 5.7e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 KXS18426.1 - 1.4e-07 31.6 0.0 7.8e-07 29.2 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Vps4_C PF09336.10 KXS18426.1 - 2.3e-07 30.7 0.0 5e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain RuvB_N PF05496.12 KXS18426.1 - 6.6e-07 29.2 0.0 4e-06 26.7 0.0 2.0 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KXS18426.1 - 1e-05 26.0 0.6 0.0007 20.0 0.0 2.5 2 1 1 3 3 2 1 AAA ATPase domain TIP49 PF06068.13 KXS18426.1 - 2.9e-05 23.5 0.0 5.3e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 KXS18426.1 - 0.00017 21.9 0.4 0.0099 16.1 0.3 2.7 1 1 1 2 2 1 1 AAA domain AAA_2 PF07724.14 KXS18426.1 - 0.00052 20.2 0.0 0.00079 19.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_25 PF13481.6 KXS18426.1 - 0.0014 18.2 0.6 0.04 13.5 0.1 2.4 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.6 KXS18426.1 - 0.0017 18.7 0.0 0.0034 17.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KXS18426.1 - 0.002 17.9 0.0 0.0032 17.2 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein DUF815 PF05673.13 KXS18426.1 - 0.0032 16.7 0.0 0.005 16.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) TniB PF05621.11 KXS18426.1 - 0.0051 16.2 0.0 6.5 6.1 0.0 3.0 2 1 1 3 3 3 0 Bacterial TniB protein AAA_14 PF13173.6 KXS18426.1 - 0.0054 16.8 0.0 0.0087 16.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KXS18426.1 - 0.0061 16.0 0.1 0.019 14.4 0.1 1.8 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 KXS18426.1 - 0.0068 15.9 0.0 0.014 14.9 0.0 1.5 1 1 0 1 1 1 1 P-loop containing dynein motor region Parvo_NS1 PF01057.17 KXS18426.1 - 0.0079 15.3 0.0 0.013 14.6 0.0 1.2 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 RNA_helicase PF00910.22 KXS18426.1 - 0.0083 16.5 0.0 0.018 15.5 0.0 1.6 1 0 0 1 1 1 1 RNA helicase Sigma54_activat PF00158.26 KXS18426.1 - 0.0091 15.7 0.0 0.13 12.0 0.0 2.2 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_18 PF13238.6 KXS18426.1 - 0.012 16.1 0.0 0.022 15.3 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KXS18426.1 - 0.019 14.7 0.1 0.04 13.6 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KXS18426.1 - 0.023 14.9 0.0 0.04 14.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_21 PF13304.6 KXS18426.1 - 0.026 14.4 0.1 1.9 8.2 0.0 2.2 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_28 PF13521.6 KXS18426.1 - 0.047 13.9 0.0 0.1 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 KXS18426.1 - 0.057 12.9 0.0 0.098 12.1 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein DUF2075 PF09848.9 KXS18426.1 - 0.08 12.2 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 KXS18426.1 - 0.087 12.5 0.1 0.2 11.4 0.1 1.6 1 1 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.6 KXS18426.1 - 0.089 12.9 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_3 PF07726.11 KXS18426.1 - 0.1 12.5 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 KXS18426.1 - 0.1 12.5 0.1 2.1 8.3 0.0 2.2 1 1 1 2 2 2 0 NACHT domain KAP_NTPase PF07693.14 KXS18426.1 - 0.14 11.4 0.1 5.3 6.2 0.1 2.2 1 1 1 2 2 2 0 KAP family P-loop domain TsaE PF02367.17 KXS18426.1 - 0.15 12.1 0.0 0.25 11.3 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase PF06745.13 KXS18426.1 - 0.15 11.4 0.1 0.82 9.0 0.1 2.0 1 1 1 2 2 2 0 KaiC AAA_11 PF13086.6 KXS18426.1 - 0.22 11.3 0.0 0.33 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain Bac_DnaA PF00308.18 KXS18426.1 - 0.23 11.3 0.0 1.4 8.7 0.0 1.9 1 1 0 1 1 1 0 Bacterial dnaA protein Cyclin_N PF00134.23 KXS18428.1 - 4.5e-13 49.1 0.0 6.9e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain NIR_SIR PF01077.22 KXS18428.1 - 0.072 12.6 0.0 0.092 12.2 0.0 1.3 1 0 0 1 1 1 0 Nitrite and sulphite reductase 4Fe-4S domain Cyclin_C_2 PF16899.5 KXS18428.1 - 0.089 13.2 1.0 0.46 10.9 1.0 2.2 1 1 0 1 1 1 0 Cyclin C-terminal domain BAAT_C PF08840.11 KXS18428.1 - 0.13 12.2 0.0 0.21 11.5 0.0 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF2838 PF10998.8 KXS18429.1 - 1.7e-34 118.4 2.8 1.7e-34 118.4 2.8 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2838) Polysacc_deac_1 PF01522.21 KXS18429.1 - 0.08 12.8 0.2 0.67 9.9 0.0 2.2 2 0 0 2 2 2 0 Polysaccharide deacetylase COX17 PF05051.13 KXS18430.1 - 5.2e-21 74.7 9.5 6.4e-21 74.4 9.5 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) RNA_pol_L_2 PF13656.6 KXS18431.1 - 9.6e-25 86.2 0.0 1.2e-24 85.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 KXS18431.1 - 1.4e-06 27.6 0.0 2.1e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain BRCA2 PF00634.18 KXS18432.1 - 0.021 14.5 0.0 0.034 13.8 0.0 1.3 1 0 0 1 1 1 0 BRCA2 repeat CMD PF02627.20 KXS18432.1 - 0.06 13.4 0.2 0.12 12.4 0.1 1.5 2 0 0 2 2 2 0 Carboxymuconolactone decarboxylase family DUF455 PF04305.14 KXS18433.1 - 7.2e-90 300.8 0.0 8.3e-90 300.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF455) TT_ORF2 PF02957.15 KXS18433.1 - 0.23 12.4 1.0 2.9 8.8 0.2 2.3 2 0 0 2 2 2 0 TT viral ORF2 Kinesin PF00225.23 KXS18436.1 - 8.8e-88 294.4 0.0 1e-87 294.2 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KXS18436.1 - 6.6e-26 91.0 0.0 1.3e-25 90.1 0.0 1.5 1 1 0 1 1 1 1 Microtubule binding PIF1 PF05970.14 KXS18436.1 - 0.18 11.0 0.2 0.26 10.4 0.2 1.1 1 0 0 1 1 1 0 PIF1-like helicase MerR-DNA-bind PF09278.11 KXS18437.1 - 2 9.0 6.5 8.3 7.0 0.7 3.7 4 0 0 4 4 4 0 MerR, DNA binding Complex1_49kDa PF00346.19 KXS18438.1 - 3.6e-123 410.0 0.0 4.9e-123 409.5 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.19 KXS18438.1 - 0.00057 18.9 0.0 0.0021 17.1 0.0 1.8 1 1 1 2 2 2 1 Nickel-dependent hydrogenase CENP-X PF09415.10 KXS18439.1 - 8.4e-20 70.9 0.6 9.3e-20 70.7 0.6 1.0 1 0 0 1 1 1 1 CENP-S associating Centromere protein X CBFD_NFYB_HMF PF00808.23 KXS18439.1 - 0.05 13.9 0.2 0.067 13.5 0.2 1.2 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone P16-Arc PF04699.14 KXS18440.1 - 1.3e-28 100.4 0.0 1.7e-28 100.0 0.0 1.2 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) NMO PF03060.15 KXS18441.1 - 1.9e-56 191.9 3.6 2.5e-56 191.5 3.6 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase FMN_dh PF01070.18 KXS18441.1 - 2.9e-06 26.6 2.7 4.3e-06 26.0 2.7 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 KXS18441.1 - 5.1e-06 25.7 4.1 2.2e-05 23.7 4.1 1.9 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain RuvA_C PF07499.13 KXS18441.1 - 0.081 13.4 0.0 0.21 12.1 0.0 1.7 1 0 0 1 1 1 0 RuvA, C-terminal domain Glu_synthase PF01645.17 KXS18441.1 - 0.16 11.1 3.4 0.28 10.3 3.4 1.3 1 0 0 1 1 1 0 Conserved region in glutamate synthase ASD2 PF08687.11 KXS18442.1 - 0.046 13.3 1.3 0.083 12.4 1.2 1.4 1 1 0 1 1 1 0 Apx/Shroom domain ASD2 Cnd1 PF12717.7 KXS18444.1 - 5.9e-14 52.4 0.3 6.7e-12 45.8 0.1 3.5 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KXS18444.1 - 0.00027 20.9 7.8 6.3 7.4 0.0 5.7 5 0 0 5 5 5 3 HEAT repeat HEAT_2 PF13646.6 KXS18444.1 - 0.0035 17.7 7.0 0.13 12.7 0.1 4.8 4 1 1 5 5 5 1 HEAT repeats Adaptin_N PF01602.20 KXS18444.1 - 0.012 14.2 0.8 0.055 12.0 0.2 2.1 2 1 2 4 4 4 0 Adaptin N terminal region DUF5610 PF18433.1 KXS18445.1 - 0.58 10.7 2.1 0.5 10.9 0.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5610) FLILHELTA PF10306.9 KXS18446.1 - 7e-13 48.8 0.0 1.3e-12 47.9 0.0 1.4 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA DUF1279 PF06916.13 KXS18446.1 - 0.017 15.7 0.7 0.037 14.6 0.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1279) zf-H2C2_2 PF13465.6 KXS18447.1 - 1.2e-08 35.0 6.2 0.00039 20.7 0.4 2.4 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 KXS18447.1 - 1.5e-05 25.2 12.5 2.1e-05 24.7 1.2 3.2 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXS18447.1 - 9.5e-05 22.9 7.2 0.0014 19.3 1.0 2.8 3 0 0 3 3 3 1 C2H2-type zinc finger zf-TRAF PF02176.18 KXS18447.1 - 0.00015 22.4 1.2 0.00029 21.5 0.8 1.6 1 1 1 2 2 2 1 TRAF-type zinc finger zf-met PF12874.7 KXS18447.1 - 0.00057 20.2 0.6 0.087 13.2 0.0 2.3 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 KXS18447.1 - 0.0013 18.4 0.1 0.003 17.3 0.1 1.6 1 0 0 1 1 1 1 zinc-finger C2H2-type zf-C2H2_9 PF16293.5 KXS18447.1 - 0.007 16.2 0.1 0.045 13.6 0.0 2.1 2 1 0 2 2 2 1 C2H2 type zinc-finger (1 copy) zf-C2H2_jaz PF12171.8 KXS18447.1 - 0.037 14.3 0.3 7.2 7.0 0.0 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding GATA PF00320.27 KXS18447.1 - 0.047 13.3 1.8 0.07 12.8 0.1 2.0 2 0 0 2 2 2 0 GATA zinc finger FOXP-CC PF16159.5 KXS18447.1 - 0.072 13.7 1.2 3.2 8.5 0.0 2.3 2 1 1 3 3 2 0 FOXP coiled-coil domain Zn_Tnp_IS1595 PF12760.7 KXS18447.1 - 0.11 12.5 3.3 0.18 11.8 3.0 1.6 1 1 0 1 1 1 0 Transposase zinc-ribbon domain zf-H2C2_5 PF13909.6 KXS18447.1 - 1 9.2 4.1 0.86 9.4 0.3 2.4 2 0 0 2 2 2 0 C2H2-type zinc-finger domain ATG_C PF09333.11 KXS18448.1 - 0.13 12.6 1.5 1.4 9.3 1.5 2.4 1 1 0 1 1 1 0 Autophagy-related protein C terminal domain DUF2142 PF09913.9 KXS18449.1 - 0.045 12.6 0.1 0.049 12.5 0.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2142) PTR2 PF00854.21 KXS18450.1 - 2.1e-79 267.2 9.2 3e-79 266.7 9.2 1.2 1 0 0 1 1 1 1 POT family DUF2834 PF11196.8 KXS18450.1 - 2.8 8.3 10.3 0.48 10.8 1.1 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF2834) Arteri_Gl PF00951.18 KXS18450.1 - 2.8 7.7 8.0 0.5 10.2 1.2 2.4 2 0 0 2 2 2 0 Arterivirus GL envelope glycoprotein DUF334 PF03904.13 KXS18450.1 - 3.2 7.2 6.5 0.81 9.2 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF334) Snapin_Pallidin PF14712.6 KXS18452.1 - 0.0063 16.9 0.9 0.016 15.6 0.6 1.7 1 1 0 1 1 1 1 Snapin/Pallidin Laminin_I PF06008.14 KXS18452.1 - 0.0072 16.1 0.3 0.0076 16.0 0.3 1.0 1 0 0 1 1 1 1 Laminin Domain I DUF3552 PF12072.8 KXS18452.1 - 0.012 15.0 0.7 0.014 14.8 0.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) ArAE_2_N PF10337.9 KXS18452.1 - 0.1 11.6 0.1 0.11 11.5 0.1 1.0 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal DUF4349 PF14257.6 KXS18452.1 - 0.62 9.5 3.8 0.81 9.1 3.6 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4349) Cnn_1N PF07989.11 KXS18453.1 - 1e-15 57.6 3.8 1e-15 57.6 3.8 9.0 5 3 3 9 9 9 2 Centrosomin N-terminal motif 1 Fez1 PF06818.15 KXS18453.1 - 0.0012 19.4 7.8 0.0012 19.4 7.8 6.3 2 2 3 5 5 5 1 Fez1 NPV_P10 PF05531.12 KXS18453.1 - 0.19 12.2 15.6 20 5.8 0.1 6.6 7 0 0 7 7 7 0 Nucleopolyhedrovirus P10 protein CCDC92 PF14916.6 KXS18453.1 - 0.57 10.0 8.1 19 5.1 0.0 4.6 5 0 0 5 5 5 0 Coiled-coil domain of unknown function Spc7 PF08317.11 KXS18453.1 - 1.4 7.7 84.3 0.12 11.2 8.3 6.6 2 2 5 8 8 8 0 Spc7 kinetochore protein Baculo_PEP_C PF04513.12 KXS18453.1 - 3.1 7.8 17.0 3.4 7.7 0.6 5.4 5 0 0 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 KXS18453.1 - 5.6 7.0 39.5 3.4 7.7 3.0 7.0 6 1 1 7 7 7 0 Protein of unknown function (DUF1664) DHHA2 PF02833.14 KXS18458.1 - 2.2e-17 63.6 0.1 3.4e-17 63.0 0.1 1.3 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.20 KXS18458.1 - 1.1e-10 41.6 0.0 2.6e-10 40.4 0.0 1.7 2 0 0 2 2 2 1 DHH family Hydrolase_4 PF12146.8 KXS18459.1 - 0.00013 21.3 0.0 0.54 9.5 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 LIDHydrolase PF10230.9 KXS18459.1 - 0.0003 20.4 0.1 0.0013 18.4 0.0 1.8 2 0 0 2 2 2 1 Lipid-droplet associated hydrolase Abhydrolase_1 PF00561.20 KXS18459.1 - 0.00084 19.1 0.0 1.4 8.5 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold PGAP1 PF07819.13 KXS18459.1 - 0.0013 18.5 0.1 0.0038 17.0 0.0 1.7 2 0 0 2 2 2 1 PGAP1-like protein LCAT PF02450.15 KXS18459.1 - 0.0027 16.9 0.1 0.017 14.3 0.0 1.9 2 0 0 2 2 2 1 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.7 KXS18459.1 - 0.0075 16.9 0.0 0.23 12.0 0.0 2.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KXS18459.1 - 0.012 15.2 0.0 0.023 14.1 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Esterase PF00756.20 KXS18459.1 - 0.051 13.2 0.0 0.094 12.3 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Lipase_3 PF01764.25 KXS18459.1 - 0.13 12.2 0.0 0.33 10.8 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) DUF676 PF05057.14 KXS18459.1 - 0.16 11.5 0.0 0.53 9.7 0.0 1.8 2 0 0 2 2 2 0 Putative serine esterase (DUF676) Mob1_phocein PF03637.17 KXS18460.1 - 1.1e-56 191.5 0.1 1.4e-56 191.1 0.1 1.0 1 0 0 1 1 1 1 Mob1/phocein family MORN PF02493.20 KXS18461.1 - 1.5e-33 112.7 24.5 1.6e-07 30.8 0.8 6.3 6 0 0 6 6 6 6 MORN repeat ECR1_N PF14382.6 KXS18461.1 - 0.59 10.0 8.1 7.5 6.4 0.2 4.1 3 1 0 3 3 3 0 Exosome complex exonuclease RRP4 N-terminal region DUF3395 PF11875.8 KXS18462.1 - 1.8e-36 125.4 0.0 3.6e-36 124.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3395) DnaJ PF00226.31 KXS18462.1 - 3.5e-19 68.7 2.6 3.5e-19 68.7 2.6 1.9 2 0 0 2 2 2 1 DnaJ domain FlgN PF05130.12 KXS18462.1 - 0.095 13.2 0.1 0.19 12.2 0.1 1.5 1 0 0 1 1 1 0 FlgN protein Glyco_transf_20 PF00982.21 KXS18463.1 - 4.9e-174 579.5 0.0 5.5e-174 579.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glycos_transf_1 PF00534.20 KXS18463.1 - 0.00092 18.8 0.1 0.067 12.7 0.0 2.6 3 0 0 3 3 3 2 Glycosyl transferases group 1 PBECR2 PF18810.1 KXS18463.1 - 0.072 13.4 0.1 0.53 10.6 0.0 2.2 2 0 0 2 2 2 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease2 Pkinase PF00069.25 KXS18464.1 - 6.6e-75 251.9 0.0 7.8e-75 251.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS18464.1 - 1.5e-34 119.4 0.0 2.1e-34 119.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KXS18464.1 - 0.0048 15.9 0.0 0.04 12.9 0.0 2.0 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KXS18464.1 - 0.006 15.9 0.0 0.017 14.5 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KXS18464.1 - 0.021 14.2 0.1 0.037 13.4 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXS18464.1 - 0.11 12.4 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family DNA_methylase PF00145.17 KXS18465.1 - 1.6e-23 83.6 0.0 1e-22 81.0 0.0 2.2 2 1 0 2 2 2 1 C-5 cytosine-specific DNA methylase Macoilin PF09726.9 KXS18466.1 - 6.5 5.2 5.9 9.2 4.7 5.9 1.3 1 0 0 1 1 1 0 Macoilin family SNF2_N PF00176.23 KXS18467.1 - 4.5e-64 216.4 0.2 6.3e-64 215.9 0.2 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KXS18467.1 - 1.4e-19 70.4 0.0 3.7e-19 69.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXS18467.1 - 2.3e-07 31.0 0.0 5.5e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KXS18467.1 - 0.00056 19.7 0.0 0.0018 18.1 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase DEAD_2 PF06733.15 KXS18467.1 - 0.094 12.3 0.0 0.49 10.0 0.0 2.2 2 0 0 2 2 2 0 DEAD_2 ERCC3_RAD25_C PF16203.5 KXS18467.1 - 0.15 11.2 0.0 0.25 10.5 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Bromodomain PF00439.25 KXS18468.1 - 2e-32 111.1 0.0 7.4e-17 61.2 0.1 2.3 2 0 0 2 2 2 2 Bromodomain BAH PF01426.18 KXS18468.1 - 4.3e-17 62.1 0.1 7e-17 61.4 0.1 1.4 1 0 0 1 1 1 1 BAH domain SLATT_5 PF18160.1 KXS18472.1 - 0.22 10.8 4.4 0.62 9.4 4.4 1.7 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 DcpS_C PF11969.8 KXS18475.1 - 3.7e-22 79.0 0.8 5.7e-22 78.3 0.8 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 KXS18475.1 - 1.9e-12 47.8 0.1 3.5e-12 46.9 0.1 1.4 1 0 0 1 1 1 1 HIT domain zf-C2HE PF16278.5 KXS18475.1 - 4.2e-09 36.7 0.5 1e-08 35.4 0.5 1.6 1 0 0 1 1 1 1 C2HE / C2H2 / C2HC zinc-binding finger Clathrin PF00637.20 KXS18477.1 - 7e-19 68.1 0.0 6.2e-13 48.8 0.0 2.8 2 0 0 2 2 2 2 Region in Clathrin and VPS Vps39_2 PF10367.9 KXS18477.1 - 0.0012 19.3 0.0 0.0027 18.1 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 zf-RING_11 PF17123.5 KXS18477.1 - 0.061 13.1 2.0 0.14 12.0 2.0 1.6 1 0 0 1 1 1 0 RING-like zinc finger PHD PF00628.29 KXS18477.1 - 0.22 11.4 0.7 1 9.3 0.2 2.3 2 0 0 2 2 2 0 PHD-finger zf-RING_2 PF13639.6 KXS18477.1 - 0.32 11.4 4.4 0.21 11.9 0.6 2.2 2 0 0 2 2 2 0 Ring finger domain zf-RING_5 PF14634.6 KXS18477.1 - 0.52 10.3 2.1 0.46 10.5 0.3 1.8 2 0 0 2 2 2 0 zinc-RING finger domain zf-rbx1 PF12678.7 KXS18477.1 - 0.58 10.5 3.1 0.33 11.3 0.3 2.0 2 0 0 2 2 2 0 RING-H2 zinc finger domain SGT1 PF07093.11 KXS18478.1 - 2.1e-66 224.6 0.0 6.8e-65 219.6 0.0 2.6 1 1 0 1 1 1 1 SGT1 protein IFT81_CH PF18383.1 KXS18479.1 - 6.2e-11 42.6 0.0 5.2e-10 39.6 0.0 2.4 2 0 0 2 2 2 1 Intraflagellar transport 81 calponin homology domain UPF0242 PF06785.11 KXS18479.1 - 1.3 9.0 38.1 0.53 10.4 3.6 4.4 2 1 1 4 4 4 0 Uncharacterised protein family (UPF0242) N-terminus Bacillus_HBL PF05791.11 KXS18479.1 - 5.4 6.8 6.6 6.8 6.5 0.2 3.6 4 0 0 4 4 4 0 Bacillus haemolytic enterotoxin (HBL) DUF1681 PF07933.14 KXS18481.1 - 4.4e-55 185.5 0.0 5.2e-55 185.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) Kinesin PF00225.23 KXS18482.1 - 1.5e-113 379.1 0.0 1.7e-113 378.9 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KXS18482.1 - 1.8e-25 89.6 0.0 3.3e-25 88.8 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding IstB_IS21 PF01695.17 KXS18482.1 - 0.14 11.9 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Glycos_transf_1 PF00534.20 KXS18483.1 - 1.8e-14 53.6 0.0 4.6e-14 52.3 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KXS18483.1 - 6.2e-09 36.4 0.0 1.3e-08 35.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 AAA PF00004.29 KXS18484.1 - 5.2e-44 149.9 0.0 9.1e-44 149.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 KXS18484.1 - 2.6e-23 81.8 0.0 8.5e-23 80.1 0.0 2.0 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 KXS18484.1 - 4.1e-20 71.6 6.9 4.1e-20 71.6 6.9 1.9 2 0 0 2 2 1 1 MIT (microtubule interacting and transport) domain AAA_lid_3 PF17862.1 KXS18484.1 - 5.9e-09 35.6 0.3 7.9e-08 32.0 0.0 2.8 4 0 0 4 4 3 1 AAA+ lid domain RuvB_N PF05496.12 KXS18484.1 - 3e-06 27.1 0.0 6e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 KXS18484.1 - 1.5e-05 25.1 0.0 4.2e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 KXS18484.1 - 1.6e-05 25.0 0.1 8.3e-05 22.6 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KXS18484.1 - 1.6e-05 25.3 0.3 0.00031 21.2 0.1 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KXS18484.1 - 3.1e-05 24.3 0.2 0.01 16.1 0.1 2.5 1 1 1 2 2 2 1 AAA domain TIP49 PF06068.13 KXS18484.1 - 3.6e-05 23.2 0.0 5.6e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain IstB_IS21 PF01695.17 KXS18484.1 - 4.7e-05 23.2 0.0 0.0001 22.1 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.6 KXS18484.1 - 6.8e-05 22.9 0.0 0.00017 21.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 KXS18484.1 - 0.0004 19.6 0.0 0.0022 17.2 0.0 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF815) AAA_33 PF13671.6 KXS18484.1 - 0.00044 20.4 0.1 0.0011 19.1 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_18 PF13238.6 KXS18484.1 - 0.0019 18.7 0.0 0.0068 16.9 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_24 PF13479.6 KXS18484.1 - 0.0057 16.4 1.4 0.013 15.2 0.0 2.2 2 1 0 2 2 2 1 AAA domain USP8_dimer PF08969.11 KXS18484.1 - 0.0065 16.7 6.2 0.016 15.4 6.2 1.6 1 0 0 1 1 1 1 USP8 dimerisation domain NACHT PF05729.12 KXS18484.1 - 0.0086 16.0 0.0 0.27 11.1 0.0 2.3 1 1 1 2 2 2 1 NACHT domain PhoH PF02562.16 KXS18484.1 - 0.01 15.3 0.2 0.027 13.9 0.2 1.6 1 0 0 1 1 1 0 PhoH-like protein ATPase PF06745.13 KXS18484.1 - 0.012 15.0 0.4 4.2 6.6 0.1 2.5 1 1 1 2 2 2 0 KaiC RNA_helicase PF00910.22 KXS18484.1 - 0.013 15.9 0.0 0.053 13.9 0.0 2.1 2 0 0 2 2 1 0 RNA helicase AAA_17 PF13207.6 KXS18484.1 - 0.014 15.8 0.7 0.035 14.5 0.0 2.1 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 KXS18484.1 - 0.015 14.8 1.0 1.2 8.7 0.1 2.7 2 1 1 3 3 3 0 AAA domain Tma16 PF11176.8 KXS18484.1 - 0.023 14.6 2.5 0.061 13.2 1.9 2.0 2 0 0 2 2 2 0 Translation machinery-associated protein 16 Hydin_ADK PF17213.3 KXS18484.1 - 0.024 14.9 2.0 4.7 7.5 0.3 2.4 2 1 0 2 2 2 0 Hydin Adenylate kinase-like domain AAA_7 PF12775.7 KXS18484.1 - 0.026 14.0 0.0 0.11 12.1 0.0 2.0 1 1 0 1 1 1 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 KXS18484.1 - 0.028 13.8 0.0 0.056 12.8 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ATPase_2 PF01637.18 KXS18484.1 - 0.03 14.2 3.8 4.8 7.0 0.0 3.5 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea TniB PF05621.11 KXS18484.1 - 0.031 13.7 0.0 9.1 5.6 0.0 2.5 1 1 1 2 2 2 0 Bacterial TniB protein Bac_DnaA PF00308.18 KXS18484.1 - 0.055 13.3 0.0 0.3 10.9 0.0 2.1 2 1 0 2 2 2 0 Bacterial dnaA protein Parvo_NS1 PF01057.17 KXS18484.1 - 0.069 12.2 0.1 0.22 10.6 0.0 1.8 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 TsaE PF02367.17 KXS18484.1 - 0.087 12.8 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 KXS18484.1 - 0.11 12.7 0.0 0.29 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 KXS18484.1 - 0.14 11.9 0.0 0.31 10.7 0.0 1.6 2 0 0 2 2 1 0 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 KXS18484.1 - 0.24 11.7 1.2 0.88 9.9 0.1 2.3 2 1 0 2 2 2 0 AAA domain AAA PF00004.29 KXS18485.1 - 2.7e-42 144.3 0.0 4.1e-42 143.7 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 KXS18485.1 - 2.6e-20 72.2 0.2 8.6e-20 70.5 0.2 2.0 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 KXS18485.1 - 4.5e-13 49.0 6.4 8.6e-13 48.2 6.4 1.5 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain AAA_lid_3 PF17862.1 KXS18485.1 - 6.6e-08 32.2 0.0 2.5e-07 30.4 0.0 2.0 2 0 0 2 2 1 1 AAA+ lid domain TIP49 PF06068.13 KXS18485.1 - 4.2e-05 22.9 0.0 6.9e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain RuvB_N PF05496.12 KXS18485.1 - 5.5e-05 23.0 0.0 0.0001 22.1 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KXS18485.1 - 6.5e-05 22.9 0.0 0.0016 18.5 0.0 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 KXS18485.1 - 8.5e-05 22.4 0.0 0.00016 21.4 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.6 KXS18485.1 - 0.00012 22.4 0.1 0.027 14.7 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 KXS18485.1 - 0.00022 21.7 0.0 0.0083 16.5 0.0 2.3 1 1 0 2 2 2 1 AAA ATPase domain AAA_2 PF07724.14 KXS18485.1 - 0.0019 18.3 0.0 0.0044 17.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 KXS18485.1 - 0.0021 18.6 0.0 0.0046 17.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KXS18485.1 - 0.0025 17.9 0.0 0.0048 16.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KXS18485.1 - 0.004 17.5 0.0 0.12 12.7 0.0 2.3 2 0 0 2 2 2 1 RNA helicase AAA_33 PF13671.6 KXS18485.1 - 0.0071 16.5 0.0 0.013 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 KXS18485.1 - 0.023 14.1 0.1 0.045 13.2 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein TniB PF05621.11 KXS18485.1 - 0.034 13.5 0.0 5 6.5 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein AAA_24 PF13479.6 KXS18485.1 - 0.035 13.8 0.0 0.078 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KXS18485.1 - 0.036 13.6 0.1 2.7 7.5 0.1 2.3 1 1 1 2 2 2 0 AAA domain DUF815 PF05673.13 KXS18485.1 - 0.039 13.1 0.0 0.1 11.7 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF815) Mg_chelatase PF01078.21 KXS18485.1 - 0.04 13.3 0.0 0.081 12.3 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Bac_DnaA PF00308.18 KXS18485.1 - 0.062 13.1 0.0 0.31 10.8 0.0 2.0 1 1 0 1 1 1 0 Bacterial dnaA protein AAA_17 PF13207.6 KXS18485.1 - 0.073 13.5 0.0 0.19 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 KXS18485.1 - 0.1 11.7 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activ_2 PF14532.6 KXS18485.1 - 0.11 12.7 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_7 PF12775.7 KXS18485.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_30 PF13604.6 KXS18485.1 - 0.13 11.9 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 KXS18485.1 - 0.14 11.4 0.1 8.6 5.6 0.1 2.2 1 1 0 2 2 2 0 KaiC Torsin PF06309.11 KXS18485.1 - 0.2 11.7 0.0 0.38 10.8 0.0 1.4 1 0 0 1 1 1 0 Torsin RabGAP-TBC PF00566.18 KXS18486.1 - 8.6e-11 41.9 2.8 2.2e-10 40.6 2.8 1.7 1 0 0 1 1 1 1 Rab-GTPase-TBC domain zf-C2H2_9 PF16293.5 KXS18486.1 - 0.13 12.1 0.3 0.32 10.9 0.3 1.6 1 0 0 1 1 1 0 C2H2 type zinc-finger (1 copy) FKBP_C PF00254.28 KXS18487.1 - 7.1e-36 122.4 0.0 8.2e-36 122.2 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase HAD_2 PF13419.6 KXS18488.1 - 2.3e-18 66.9 0.0 3.2e-18 66.4 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KXS18488.1 - 2.1e-12 47.8 0.1 3.9e-11 43.6 0.1 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KXS18488.1 - 5.1e-05 23.8 0.0 6.5e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 KXS18488.1 - 0.0011 19.0 0.1 0.42 10.7 0.0 2.5 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase GYF PF02213.16 KXS18489.1 - 5.2e-17 61.3 0.8 1e-16 60.3 0.8 1.5 1 0 0 1 1 1 1 GYF domain GYF_2 PF14237.6 KXS18489.1 - 0.00059 19.6 0.1 0.0013 18.5 0.1 1.6 1 0 0 1 1 1 1 GYF domain 2 HTH_23 PF13384.6 KXS18490.1 - 0.00069 19.3 0.2 0.083 12.7 0.0 2.6 2 0 0 2 2 2 1 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KXS18490.1 - 0.0019 18.4 0.1 0.026 14.8 0.1 2.3 2 0 0 2 2 2 1 Transposase HTH_Tnp_IS630 PF01710.16 KXS18490.1 - 0.0032 17.5 0.0 0.008 16.2 0.0 1.7 1 1 0 1 1 1 1 Transposase HTH_33 PF13592.6 KXS18490.1 - 0.004 16.8 0.0 0.01 15.5 0.0 1.7 1 0 0 1 1 1 1 Winged helix-turn helix HTH_29 PF13551.6 KXS18490.1 - 0.0088 16.1 0.3 0.13 12.3 0.0 2.8 3 0 0 3 3 3 1 Winged helix-turn helix TCTP PF00838.17 KXS18490.1 - 0.18 12.2 0.0 0.26 11.6 0.0 1.3 1 0 0 1 1 1 0 Translationally controlled tumour protein TetR_C_16 PF17920.1 KXS18492.1 - 0.024 14.8 1.0 0.045 14.0 1.0 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain OrfB_Zn_ribbon PF07282.11 KXS18494.1 - 8e-06 25.7 6.2 2.6e-05 24.0 4.7 2.3 2 1 0 2 2 2 1 Putative transposase DNA-binding domain ANAPC4_WD40 PF12894.7 KXS18495.1 - 2e-15 56.8 0.0 0.00083 19.6 0.0 5.3 3 1 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KXS18495.1 - 6.2e-06 26.9 25.5 2.1 9.4 0.0 8.7 10 1 1 11 11 11 4 WD domain, G-beta repeat PQQ_2 PF13360.6 KXS18495.1 - 0.072 12.7 8.4 0.086 12.4 1.1 3.5 3 2 1 4 4 4 0 PQQ-like domain IRF PF00605.17 KXS18495.1 - 0.12 12.6 0.0 0.31 11.4 0.0 1.6 1 0 0 1 1 1 0 Interferon regulatory factor transcription factor PPP4R2 PF09184.11 KXS18496.1 - 0.007 16.0 7.0 0.017 14.7 7.0 1.6 1 0 0 1 1 1 1 PPP4R2 NAP PF00956.18 KXS18496.1 - 0.41 9.8 3.1 0.61 9.2 3.1 1.1 1 0 0 1 1 1 0 Nucleosome assembly protein (NAP) CDC27 PF09507.10 KXS18496.1 - 4.4 6.6 16.4 0.016 14.6 6.2 2.2 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 NUDIX PF00293.28 KXS18498.1 - 4.7e-08 33.1 0.0 8.3e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain TCO89 PF10452.9 KXS18501.1 - 0.13 11.2 0.0 0.22 10.4 0.0 1.3 1 0 0 1 1 1 0 TORC1 subunit TCO89 EDR1 PF14381.6 KXS18502.1 - 0.22 11.2 0.0 0.33 10.7 0.0 1.2 1 0 0 1 1 1 0 Ethylene-responsive protein kinase Le-CTR1 DUF3552 PF12072.8 KXS18504.1 - 0.0019 17.7 1.3 0.0029 17.0 1.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) Acyl-CoA_dh_1 PF00441.24 KXS18505.1 - 5.7e-37 127.2 1.7 8.2e-37 126.7 1.7 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.28 KXS18505.1 - 1.7e-22 79.3 0.1 5.2e-22 77.8 0.0 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.19 KXS18505.1 - 1.9e-21 76.1 0.4 5.6e-21 74.5 0.2 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KXS18505.1 - 1.3e-20 74.1 0.0 3.8e-20 72.6 0.0 1.9 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KXS18505.1 - 1.3e-07 31.9 0.4 2.4e-07 31.1 0.4 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Hemerythrin PF01814.23 KXS18506.1 - 5.4e-10 40.0 1.4 8.4e-10 39.4 1.4 1.3 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain MYCBPAP PF14646.6 KXS18507.1 - 8.1e-31 107.4 0.0 1.3e-29 103.5 0.0 2.6 1 1 0 1 1 1 1 MYCBP-associated protein family Usp PF00582.26 KXS18508.1 - 3.5e-25 89.2 0.1 4.3e-25 88.9 0.1 1.1 1 0 0 1 1 1 1 Universal stress protein family MreC PF04085.14 KXS18508.1 - 0.014 15.3 0.0 0.02 14.8 0.0 1.2 1 0 0 1 1 1 0 rod shape-determining protein MreC AMP-binding PF00501.28 KXS18509.1 - 1.5e-57 195.1 0.0 2e-57 194.7 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXS18509.1 - 9.8e-11 42.5 0.1 2.1e-10 41.4 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Polysacc_deac_1 PF01522.21 KXS18509.1 - 0.11 12.4 0.0 9.7 6.1 0.0 2.5 2 0 0 2 2 2 0 Polysaccharide deacetylase AMP-binding PF00501.28 KXS18510.1 - 2.4e-57 194.4 0.0 3.6e-57 193.9 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXS18510.1 - 1.5e-10 41.9 0.1 3.7e-10 40.6 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Pkinase PF00069.25 KXS18511.1 - 6.9e-37 127.2 0.0 1.8e-25 89.8 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXS18511.1 - 3.6e-21 75.6 0.0 1.3e-20 73.8 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXS18511.1 - 0.0018 17.1 0.0 0.0025 16.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase DALR_1 PF05746.15 KXS18512.1 - 0.014 15.6 0.0 0.029 14.6 0.0 1.6 1 0 0 1 1 1 0 DALR anticodon binding domain SoxZ PF08770.11 KXS18512.1 - 0.11 12.3 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Sulphur oxidation protein SoxZ Aim19 PF10315.9 KXS18513.1 - 2.5e-17 63.2 2.0 3.6e-17 62.7 2.0 1.2 1 0 0 1 1 1 1 Altered inheritance of mitochondria protein 19 Tmemb_14 PF03647.13 KXS18513.1 - 0.059 14.1 0.6 0.26 12.1 0.2 1.9 2 0 0 2 2 2 0 Transmembrane proteins 14C Abhydrolase_6 PF12697.7 KXS18514.1 - 1.1e-16 62.1 0.8 1.6e-16 61.6 0.8 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXS18514.1 - 4.5e-13 49.0 0.0 5.8e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KXS18514.1 - 9.9e-08 31.9 1.1 1.9e-07 31.0 0.9 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Pkinase PF00069.25 KXS18516.1 - 9.5e-74 248.1 0.0 1.3e-73 247.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS18516.1 - 8.6e-38 130.1 0.0 2e-37 128.9 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXS18516.1 - 6.3e-06 25.7 1.8 0.6 9.4 0.2 3.1 3 0 0 3 3 3 3 Kinase-like APH PF01636.23 KXS18516.1 - 0.0023 17.9 0.1 0.21 11.5 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KXS18516.1 - 0.0042 16.1 0.0 0.0064 15.5 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 KXS18516.1 - 0.011 14.6 0.0 0.028 13.2 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase Kdo PF06293.14 KXS18516.1 - 0.035 13.5 0.2 0.069 12.5 0.2 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Cyclin_N PF00134.23 KXS18518.1 - 2.5e-29 101.6 0.0 9.2e-29 99.8 0.0 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain PAP2_3 PF14378.6 KXS18518.1 - 0.0054 16.4 0.1 0.01 15.6 0.1 1.3 1 0 0 1 1 1 1 PAP2 superfamily AMP-binding PF00501.28 KXS18519.1 - 3e-58 197.4 0.0 5.4e-58 196.6 0.0 1.4 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXS18519.1 - 3.5e-07 31.1 0.0 7.6e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ECH_1 PF00378.20 KXS18520.1 - 2.9e-38 131.6 0.3 4.1e-30 104.9 0.7 2.1 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXS18520.1 - 5.5e-19 68.8 0.0 1.4e-18 67.6 0.0 1.7 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Glyco_transf_49 PF13896.6 KXS18521.1 - 3.8e-51 174.4 0.0 7.1e-38 130.8 0.0 2.1 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan LRR_12 PF18837.1 KXS18522.1 - 0.21 11.3 0.6 17 5.2 0.0 2.6 2 0 0 2 2 2 0 Leucine-rich repeat LRR_6 PF13516.6 KXS18522.1 - 8.4 6.7 7.3 14 6.0 0.4 3.5 3 0 0 3 3 3 0 Leucine Rich repeat EXS PF03124.14 KXS18523.1 - 1.2e-58 199.0 20.7 1.5e-58 198.7 20.7 1.0 1 0 0 1 1 1 1 EXS family YuiB PF14068.6 KXS18523.1 - 0.085 13.4 1.6 0.17 12.5 0.4 2.0 2 0 0 2 2 2 0 Putative membrane protein ADH_N PF08240.12 KXS18525.1 - 1.9e-07 30.9 0.1 7.6e-07 29.0 0.1 1.8 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXS18525.1 - 2.5e-07 30.7 0.0 5.2e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Gti1_Pac2 PF09729.9 KXS18527.1 - 2.9e-37 128.5 0.4 5.6e-37 127.6 0.4 1.5 1 1 0 1 1 1 1 Gti1/Pac2 family Herpes_TAF50 PF03326.13 KXS18527.1 - 0.037 12.7 0.3 0.045 12.4 0.3 1.1 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) NucS PF01939.16 KXS18527.1 - 0.12 11.7 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 Endonuclease NucS NmrA PF05368.13 KXS18528.1 - 0.0029 17.2 0.0 0.0038 16.8 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Actin PF00022.19 KXS18529.1 - 8e-12 44.5 0.0 5.5e-05 22.0 0.0 3.2 3 0 0 3 3 3 3 Actin MreB_Mbl PF06723.13 KXS18529.1 - 5.6e-07 28.7 0.1 2.3e-06 26.7 0.0 1.8 2 0 0 2 2 2 1 MreB/Mbl protein Actin_micro PF17003.5 KXS18529.1 - 0.0023 17.2 0.0 1.8 7.7 0.0 2.2 2 0 0 2 2 2 2 Putative actin-like family FtsA PF14450.6 KXS18529.1 - 0.018 15.5 0.0 0.038 14.4 0.0 1.5 1 0 0 1 1 1 0 Cell division protein FtsA AMP-binding PF00501.28 KXS18530.1 - 5.3e-91 305.3 0.0 6.6e-91 305.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXS18530.1 - 4.5e-15 56.4 0.1 1.4e-14 54.8 0.1 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 KXS18531.1 - 6.9e-91 304.9 0.0 8.5e-91 304.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXS18531.1 - 2.5e-15 57.2 0.0 6.6e-15 55.8 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain MFS_1 PF07690.16 KXS18533.1 - 1.8e-25 89.6 67.8 2.2e-22 79.5 31.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily LRR_4 PF12799.7 KXS18534.1 - 6.4e-10 39.1 21.3 0.00012 22.3 0.1 4.0 2 1 2 4 4 4 4 Leucine Rich repeats (2 copies) SH3_9 PF14604.6 KXS18534.1 - 2.6e-08 33.6 0.0 1.1e-06 28.4 0.0 2.6 2 0 0 2 2 2 1 Variant SH3 domain LRR_8 PF13855.6 KXS18534.1 - 2.7e-07 30.2 17.6 0.00091 18.9 8.3 3.5 2 1 0 3 3 3 3 Leucine rich repeat SH3_1 PF00018.28 KXS18534.1 - 1.8e-06 27.4 0.0 3.8e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 SH3 domain LRR_1 PF00560.33 KXS18534.1 - 0.024 15.1 18.7 7.4 7.6 0.1 6.3 5 1 0 5 5 5 0 Leucine Rich Repeat Heliorhodopsin PF18761.1 KXS18535.1 - 6e-70 235.3 12.5 7.4e-70 235.0 12.5 1.0 1 0 0 1 1 1 1 Heliorhodopsin Rer1 PF03248.13 KXS18535.1 - 1.4 8.7 8.7 0.37 10.5 1.0 2.7 2 1 1 3 3 3 0 Rer1 family AstE_AspA PF04952.14 KXS18536.1 - 3.5e-06 26.3 0.3 0.00012 21.3 0.1 2.8 3 1 0 3 3 3 2 Succinylglutamate desuccinylase / Aspartoacylase family LRR_8 PF13855.6 KXS18537.1 - 0.075 12.8 7.1 0.04 13.7 3.8 2.2 1 1 0 2 2 2 0 Leucine rich repeat LRR_4 PF12799.7 KXS18537.1 - 0.32 11.5 9.2 0.12 12.8 2.4 2.7 1 1 0 2 2 2 0 Leucine Rich repeats (2 copies) HopW1-1 PF15457.6 KXS18539.1 - 0.088 12.1 0.7 0.1 11.8 0.7 1.0 1 0 0 1 1 1 0 Type III T3SS secreted effector HopW1-1/HopPmaA Exo_endo_phos_2 PF14529.6 KXS18540.1 - 0.0027 17.5 0.0 0.0062 16.4 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase HEAT_2 PF13646.6 KXS18540.1 - 0.072 13.5 1.1 0.19 12.2 1.1 1.7 1 0 0 1 1 1 0 HEAT repeats HalX PF08663.10 KXS18540.1 - 1.3 9.4 4.8 32 5.0 0.0 3.0 2 1 0 2 2 2 0 HalX domain RRM_1 PF00076.22 KXS18545.1 - 5.4e-12 45.4 0.0 8.9e-12 44.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KXS18545.1 - 0.063 13.3 0.1 0.087 12.8 0.1 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif DWNN PF08783.11 KXS18547.1 - 5.7e-23 81.0 0.0 9.8e-23 80.2 0.0 1.4 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.6 KXS18547.1 - 5.4e-05 22.9 6.1 0.00078 19.2 6.1 2.4 1 1 0 1 1 1 1 Zinc knuckle zf-C3HC4_3 PF13920.6 KXS18547.1 - 0.00011 21.9 8.3 0.00011 21.9 8.3 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) U-box PF04564.15 KXS18547.1 - 0.00015 21.9 0.0 0.00037 20.6 0.0 1.7 1 0 0 1 1 1 1 U-box domain zf-C3HC4_2 PF13923.6 KXS18547.1 - 0.012 15.4 10.5 0.025 14.4 10.5 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXS18547.1 - 0.016 15.2 7.2 0.016 15.2 7.2 1.9 2 0 0 2 2 2 0 zinc-RING finger domain zf-RING_6 PF14835.6 KXS18547.1 - 0.019 14.8 2.7 0.04 13.8 2.7 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.6 KXS18547.1 - 0.025 14.8 10.9 0.055 13.6 10.9 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 KXS18547.1 - 0.028 14.8 9.4 0.049 14.0 9.4 1.4 1 0 0 1 1 1 0 Ring finger domain zf-RING_UBOX PF13445.6 KXS18547.1 - 0.13 12.3 8.6 0.25 11.4 8.6 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-CCHC PF00098.23 KXS18547.1 - 0.18 11.9 5.9 7.9 6.8 0.1 2.5 2 0 0 2 2 2 0 Zinc knuckle zf-C3HC4 PF00097.25 KXS18547.1 - 0.32 10.9 8.9 0.63 10.0 8.9 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KXS18547.1 - 0.33 10.8 8.5 1.4 8.9 8.7 1.9 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 MGC-24 PF05283.11 KXS18547.1 - 0.77 10.2 2.0 1.9 8.9 2.0 1.7 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin zf-H2C2_2 PF13465.6 KXS18547.1 - 3 8.4 5.2 4.4 7.9 0.7 2.7 2 0 0 2 2 2 0 Zinc-finger double domain ATG16 PF08614.11 KXS18548.1 - 0.019 15.2 4.6 0.05 13.8 0.3 2.7 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) GOLGA2L5 PF15070.6 KXS18548.1 - 0.063 11.9 1.3 0.16 10.6 1.4 1.5 1 1 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 Vps53_N PF04100.12 KXS18548.1 - 0.13 11.2 0.5 0.26 10.2 0.5 1.4 1 0 0 1 1 1 0 Vps53-like, N-terminal SlyX PF04102.12 KXS18548.1 - 0.36 11.5 4.9 1.4 9.5 0.3 3.2 2 1 0 2 2 2 0 SlyX ISG65-75 PF11727.8 KXS18548.1 - 0.99 8.6 4.4 10 5.3 0.0 2.2 2 0 0 2 2 2 0 Invariant surface glycoprotein TPR_MLP1_2 PF07926.12 KXS18548.1 - 1.4 9.0 11.5 0.35 10.9 5.8 2.3 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein HIP1_clath_bdg PF16515.5 KXS18548.1 - 3.7 8.2 9.0 28 5.4 3.7 2.5 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Spc7 PF08317.11 KXS18548.1 - 5.1 5.9 9.0 11 4.8 5.7 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein COG2 PF06148.11 KXS18548.1 - 6.5 6.9 5.0 25 5.0 0.1 2.2 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 GFA PF04828.14 KXS18551.1 - 7.4e-21 74.3 7.8 3.7e-10 40.0 0.2 3.5 3 2 0 3 3 3 2 Glutathione-dependent formaldehyde-activating enzyme Ribosomal_S27 PF01599.19 KXS18551.1 - 0.88 9.8 8.7 25 5.1 0.1 3.5 3 0 0 3 3 3 0 Ribosomal protein S27a Rpr2 PF04032.16 KXS18551.1 - 5.3 7.4 0.0 5.3 7.4 0.0 3.0 4 0 0 4 4 4 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain NOB1_Zn_bind PF08772.11 KXS18551.1 - 6.4 7.0 10.6 2.5 8.3 0.2 3.0 3 0 0 3 3 3 0 Nin one binding (NOB1) Zn-ribbon like Hydrolase_4 PF12146.8 KXS18552.1 - 1.1e-11 44.5 0.0 1.7e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KXS18552.1 - 4.5e-08 33.1 0.1 9.3e-07 28.7 0.1 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold DUF915 PF06028.11 KXS18552.1 - 5.8e-05 22.5 0.0 0.00063 19.2 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) Peptidase_S9 PF00326.21 KXS18552.1 - 0.042 13.3 0.0 0.38 10.2 0.0 2.0 1 1 0 1 1 1 0 Prolyl oligopeptidase family Esterase PF00756.20 KXS18552.1 - 0.11 12.1 0.0 1.4 8.5 0.0 2.2 2 0 0 2 2 2 0 Putative esterase Xpo1 PF08389.12 KXS18553.1 - 3.2e-13 50.0 0.0 1.4e-12 47.9 0.0 2.2 2 0 0 2 2 2 1 Exportin 1-like protein IBN_N PF03810.19 KXS18553.1 - 7.1e-09 35.5 0.0 2.4e-08 33.8 0.0 2.0 2 0 0 2 2 2 1 Importin-beta N-terminal domain Importin_rep PF18773.1 KXS18553.1 - 0.021 14.5 0.0 0.055 13.2 0.0 1.7 1 0 0 1 1 1 0 Importin 13 repeat HEAT PF02985.22 KXS18553.1 - 0.049 13.9 0.4 2.9 8.4 0.0 3.9 4 0 0 4 4 4 0 HEAT repeat Herpes_UL73 PF03554.13 KXS18554.1 - 0.093 12.7 0.2 0.24 11.5 0.2 1.7 1 0 0 1 1 1 0 UL73 viral envelope glycoprotein Flp_Fap PF04964.14 KXS18558.1 - 0.054 13.3 1.3 0.098 12.5 1.3 1.4 1 0 0 1 1 1 0 Flp/Fap pilin component Disintegrin PF00200.23 KXS18559.1 - 1.4e-18 67.4 29.5 1.8e-18 67.1 29.5 1.1 1 0 0 1 1 1 1 Disintegrin TMEM208_SND2 PF05620.11 KXS18560.1 - 0.099 12.4 0.2 0.12 12.1 0.2 1.0 1 0 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 DUF1712 PF08217.11 KXS18561.1 - 6.2e-24 84.4 0.0 1e-23 83.7 0.0 1.3 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1712) SPX PF03105.19 KXS18561.1 - 0.024 14.6 2.6 0.035 14.0 2.6 1.3 1 0 0 1 1 1 0 SPX domain Ndc1_Nup PF09531.10 KXS18561.1 - 1.2 7.7 4.0 1.6 7.3 4.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Sec63 PF02889.16 KXS18562.1 - 1.5e-170 565.0 0.0 1.2e-92 309.8 0.0 2.4 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 KXS18562.1 - 1e-47 162.2 0.0 3.8e-26 91.9 0.2 2.5 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_PWI PF18149.1 KXS18562.1 - 7.3e-34 116.3 0.0 1.9e-33 114.9 0.0 1.8 1 0 0 1 1 1 1 N-terminal helicase PWI domain ResIII PF04851.15 KXS18562.1 - 4.3e-26 91.9 0.0 1.8e-14 54.1 0.0 3.0 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KXS18562.1 - 2.7e-12 47.0 0.0 2e-08 34.5 0.0 3.7 3 1 0 3 3 3 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 KXS18562.1 - 1.8e-07 31.5 0.0 0.0051 17.1 0.1 3.3 2 0 0 2 2 2 2 AAA domain PhoH PF02562.16 KXS18562.1 - 0.0019 17.7 0.0 0.36 10.2 0.0 2.6 2 0 0 2 2 2 1 PhoH-like protein AAA_11 PF13086.6 KXS18562.1 - 0.0063 16.3 2.1 0.49 10.1 0.0 3.8 3 1 1 4 4 4 1 AAA domain DUF603 PF04645.12 KXS18562.1 - 0.018 14.7 0.1 0.043 13.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF603 AAA_25 PF13481.6 KXS18562.1 - 0.026 14.1 1.2 0.31 10.6 0.0 2.8 3 0 0 3 3 3 0 AAA domain Val_tRNA-synt_C PF10458.9 KXS18562.1 - 0.16 12.3 3.7 0.31 11.3 2.2 2.3 2 0 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm Methyltransf_25 PF13649.6 KXS18563.1 - 5.9e-20 71.8 0.0 1.1e-19 70.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXS18563.1 - 5.6e-16 58.7 0.0 8.9e-16 58.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXS18563.1 - 1.5e-14 54.4 0.0 3.2e-14 53.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Dala_Dala_lig_C PF07478.13 KXS18563.1 - 3.8e-14 52.7 0.0 9.7e-14 51.4 0.0 1.6 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus Ubie_methyltran PF01209.18 KXS18563.1 - 3e-10 39.8 0.0 5.1e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KXS18563.1 - 5.5e-09 36.7 0.0 1e-08 35.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXS18563.1 - 8.8e-09 35.4 0.0 2e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXS18563.1 - 2.1e-05 24.2 0.0 3.4e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.18 KXS18563.1 - 0.00086 18.7 0.0 0.0017 17.7 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain ATP-grasp_3 PF02655.14 KXS18563.1 - 0.0047 17.0 0.0 0.01 15.9 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Methyltransf_4 PF02390.17 KXS18563.1 - 0.021 14.3 0.0 0.068 12.6 0.0 1.8 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_32 PF13679.6 KXS18563.1 - 0.036 14.1 0.0 0.086 12.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_29 PF03141.16 KXS18563.1 - 0.041 12.4 0.0 0.069 11.7 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase TehB PF03848.14 KXS18563.1 - 0.048 13.1 0.0 0.095 12.1 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB DUF938 PF06080.12 KXS18563.1 - 0.084 12.6 0.0 0.25 11.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF938) DNAPolymera_Pol PF11590.8 KXS18563.1 - 0.15 12.0 1.8 4 7.4 0.1 2.7 2 0 0 2 2 2 0 DNA polymerase catalytic subunit Pol TMEM154 PF15102.6 KXS18564.1 - 0.051 13.5 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 TMEM154 protein family Ribosomal_L12_N PF16320.5 KXS18564.1 - 0.5 10.1 0.0 0.5 10.1 0.0 2.9 2 0 0 2 2 2 0 Ribosomal protein L7/L12 dimerisation domain DOMON PF03351.17 KXS18565.1 - 3e-11 43.6 0.0 6.1e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 DOMON domain Cytochrom_B561 PF03188.16 KXS18565.1 - 6.5e-10 39.3 15.1 6.5e-10 39.3 15.1 1.6 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 CDH-cyt PF16010.5 KXS18565.1 - 7.4e-09 35.5 0.1 1.5e-08 34.5 0.1 1.5 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase DUF2427 PF10348.9 KXS18565.1 - 0.00038 20.2 8.5 0.00038 20.2 8.5 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) DUF4079 PF13301.6 KXS18565.1 - 0.3 11.2 15.9 0.12 12.5 7.6 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF4079) zf-H2C2_2 PF13465.6 KXS18566.1 - 1.2e-05 25.4 0.9 1.2e-05 25.4 0.9 2.5 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.26 KXS18566.1 - 0.0027 18.1 11.9 0.21 12.1 4.9 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXS18566.1 - 0.033 15.0 9.0 0.92 10.5 3.3 3.2 2 0 0 2 2 2 0 C2H2-type zinc finger Beta_elim_lyase PF01212.21 KXS18567.1 - 1.6e-70 237.7 0.0 1.8e-70 237.5 0.0 1.0 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 KXS18567.1 - 4.9e-06 26.0 0.0 1e-05 24.9 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II OKR_DC_1 PF01276.20 KXS18567.1 - 0.0029 16.4 0.0 0.0048 15.7 0.0 1.4 1 1 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain GATA PF00320.27 KXS18568.1 - 2.5e-28 97.4 11.7 1.7e-14 53.1 2.2 2.2 2 0 0 2 2 2 2 GATA zinc finger Zn-ribbon_8 PF09723.10 KXS18568.1 - 6.3e-05 23.0 2.0 0.04 14.0 0.1 2.3 2 0 0 2 2 2 2 Zinc ribbon domain Auto_anti-p27 PF06677.12 KXS18568.1 - 0.00026 21.1 4.6 0.038 14.2 0.4 2.3 2 0 0 2 2 2 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DZR PF12773.7 KXS18568.1 - 0.0004 20.3 4.6 0.004 17.2 4.9 2.4 1 1 1 2 2 2 1 Double zinc ribbon TF_Zn_Ribbon PF08271.12 KXS18568.1 - 0.00079 18.9 8.2 0.16 11.5 1.5 2.5 2 1 0 2 2 2 2 TFIIB zinc-binding DUF2387 PF09526.10 KXS18568.1 - 0.0013 18.8 0.2 0.73 10.0 0.1 2.1 1 1 1 2 2 2 2 Probable metal-binding protein (DUF2387) Nudix_N_2 PF14803.6 KXS18568.1 - 0.0021 17.9 11.5 0.021 14.7 2.5 2.8 2 1 0 2 2 2 2 Nudix N-terminal eIF-5_eIF-2B PF01873.17 KXS18568.1 - 0.0024 17.7 3.8 0.14 12.1 0.2 2.1 2 0 0 2 2 2 2 Domain found in IF2B/IF5 Elf1 PF05129.13 KXS18568.1 - 0.0065 16.5 0.9 6.4 6.9 0.5 3.0 2 1 1 3 3 3 1 Transcription elongation factor Elf1 like C1_1 PF00130.22 KXS18568.1 - 0.0093 15.8 3.0 0.51 10.3 0.1 2.2 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zinc_ribbon_15 PF17032.5 KXS18568.1 - 0.019 15.7 0.7 0.16 12.7 0.2 2.4 1 1 1 2 2 2 0 zinc-ribbon family Tnp_zf-ribbon_2 PF13842.6 KXS18568.1 - 0.029 15.2 3.2 3.5 8.5 0.4 3.4 2 2 1 3 3 3 0 DDE_Tnp_1-like zinc-ribbon OrfB_Zn_ribbon PF07282.11 KXS18568.1 - 0.033 14.1 6.1 0.62 10.0 0.4 2.2 2 0 0 2 2 2 0 Putative transposase DNA-binding domain C1_2 PF03107.16 KXS18568.1 - 0.15 12.4 4.0 13 6.2 0.1 3.1 2 1 1 3 3 3 0 C1 domain zf-Sec23_Sec24 PF04810.15 KXS18568.1 - 0.17 12.0 3.9 0.61 10.2 0.2 2.5 2 1 0 2 2 2 0 Sec23/Sec24 zinc finger zf-NADH-PPase PF09297.11 KXS18568.1 - 0.91 9.2 12.0 0.36 10.5 1.9 3.8 3 1 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain zf-ribbon_3 PF13248.6 KXS18568.1 - 1.2 8.6 12.9 11 5.6 0.1 4.2 4 0 0 4 4 4 0 zinc-ribbon domain zf-MYND PF01753.18 KXS18568.1 - 1.6 8.9 5.4 8.9 6.5 0.6 2.3 2 0 0 2 2 2 0 MYND finger Rubredoxin_2 PF18073.1 KXS18568.1 - 1.7 8.4 11.8 20 5.0 0.2 4.1 4 0 0 4 4 4 0 Rubredoxin metal binding domain Prim_Zn_Ribbon PF08273.12 KXS18568.1 - 6.7 7.1 11.9 2.5 8.4 0.7 3.1 2 2 0 2 2 2 0 Zinc-binding domain of primase-helicase Acetyltransf_1 PF00583.25 KXS18569.1 - 7.6e-12 45.5 0.1 9.9e-12 45.1 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXS18569.1 - 1.8e-09 37.6 0.0 2.9e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXS18569.1 - 9.3e-09 35.6 0.0 1.6e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXS18569.1 - 4.8e-06 26.5 0.0 8.5e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 KXS18569.1 - 3e-05 24.1 0.4 5.1e-05 23.3 0.4 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF2415 PF10313.9 KXS18570.1 - 1.1e-12 47.6 0.1 6.4e-12 45.2 0.0 2.3 3 0 0 3 3 3 1 Uncharacterised protein domain (DUF2415) WD40 PF00400.32 KXS18570.1 - 0.0017 19.1 5.9 4.3 8.4 0.4 5.6 5 1 1 6 6 6 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXS18570.1 - 0.0039 17.4 0.0 4.5 7.6 0.1 4.1 2 1 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Lgl_C PF08596.10 KXS18570.1 - 0.013 14.2 0.0 0.052 12.2 0.0 1.7 1 1 1 2 2 2 0 Lethal giant larvae(Lgl) like, C-terminal Coatomer_WDAD PF04053.14 KXS18570.1 - 0.047 12.7 0.7 0.21 10.6 0.1 1.8 1 1 1 2 2 2 0 Coatomer WD associated region WD40_3 PF15911.5 KXS18570.1 - 0.05 13.6 0.1 0.2 11.7 0.0 2.0 2 0 0 2 2 2 0 WD domain, G-beta repeat Frtz PF11768.8 KXS18570.1 - 0.087 11.1 0.0 0.17 10.2 0.0 1.4 1 1 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz ATP-synt_ab PF00006.25 KXS18571.1 - 3.9e-75 252.2 0.0 5.7e-75 251.6 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 KXS18571.1 - 1e-47 161.6 0.0 1.7e-47 160.9 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 KXS18571.1 - 2.1e-20 73.0 0.4 5.4e-20 71.7 0.4 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain ATPase_2 PF01637.18 KXS18571.1 - 0.02 14.8 0.0 0.037 13.9 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Acetyltransf_1 PF00583.25 KXS18572.1 - 1.4e-07 31.7 0.0 1.8e-07 31.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXS18572.1 - 2.5e-06 27.5 0.0 2.7e-06 27.3 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXS18572.1 - 1.1e-05 25.8 0.0 1.2e-05 25.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF1752 PF08550.10 KXS18573.1 - 0.0034 17.2 4.1 0.0056 16.5 4.1 1.4 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) FAM199X PF15814.5 KXS18573.1 - 4.9 6.1 7.3 7 5.6 7.3 1.2 1 0 0 1 1 1 0 Protein family FAM199X MORN PF02493.20 KXS18574.1 - 6.9e-10 38.2 22.5 0.00022 20.9 8.8 5.3 5 0 0 5 5 5 3 MORN repeat PCNA_C PF02747.15 KXS18575.1 - 2.8e-52 176.2 0.2 5.5e-52 175.3 0.0 1.5 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain PCNA_N PF00705.18 KXS18575.1 - 4.6e-52 175.0 0.7 1.1e-51 173.8 0.1 1.8 2 1 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain Rad9 PF04139.13 KXS18575.1 - 9.7e-08 31.8 0.0 1.2e-07 31.5 0.0 1.0 1 0 0 1 1 1 1 Rad9 Rad1 PF02144.16 KXS18575.1 - 0.0005 19.2 0.1 0.0073 15.4 0.1 2.4 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 HAUS2 PF15003.6 KXS18576.1 - 0.0053 16.5 0.0 0.016 14.9 0.0 1.7 2 0 0 2 2 2 1 HAUS augmin-like complex subunit 2 Mog1 PF04603.12 KXS18577.1 - 4.5e-36 124.3 0.0 5.6e-36 124.0 0.0 1.1 1 0 0 1 1 1 1 Ran-interacting Mog1 protein WD40 PF00400.32 KXS18579.1 - 1.6e-10 41.4 3.3 1.2 10.1 0.1 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXS18579.1 - 0.14 12.4 0.1 8.9 6.7 0.0 3.3 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain HEAT_2 PF13646.6 KXS18581.1 - 3.5e-09 36.9 8.2 2.5e-06 27.8 0.3 4.5 5 0 0 5 5 5 3 HEAT repeats HEAT PF02985.22 KXS18581.1 - 7e-09 35.2 12.4 0.001 19.1 0.1 6.4 7 0 0 7 7 7 2 HEAT repeat HEAT_EZ PF13513.6 KXS18581.1 - 3e-06 27.6 7.6 0.01 16.3 0.3 5.0 5 0 0 5 5 5 2 HEAT-like repeat Cnd1 PF12717.7 KXS18581.1 - 0.17 11.9 0.9 1.9 8.5 0.0 3.0 3 1 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 RhoGAP PF00620.27 KXS18582.1 - 1.2e-36 125.8 0.1 2.9e-36 124.6 0.1 1.6 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.22 KXS18582.1 - 1.1e-25 89.6 31.5 4.3e-12 46.1 4.4 4.7 4 0 0 4 4 4 4 LIM domain Desulfoferrod_N PF06397.12 KXS18582.1 - 0.012 15.2 5.2 1 9.1 0.5 3.0 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain RNA_pol_Rpb1_5 PF04998.17 KXS18584.1 - 2.3e-87 292.8 0.9 4e-87 292.0 0.9 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.12 KXS18584.1 - 1.6e-77 260.9 0.0 3.3e-77 259.9 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.20 KXS18584.1 - 6e-73 244.5 0.0 1.1e-72 243.6 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 KXS18584.1 - 8.8e-39 132.9 0.0 2.1e-38 131.7 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 KXS18584.1 - 1.1e-30 105.8 0.0 2.6e-30 104.5 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Rpr2 PF04032.16 KXS18584.1 - 0.051 13.8 0.7 0.14 12.5 0.7 1.7 1 0 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Cwf_Cwc_15 PF04889.12 KXS18585.1 - 1.8e-62 211.3 19.9 9e-62 209.0 19.9 2.5 1 1 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein SPX PF03105.19 KXS18585.1 - 1.3 8.9 18.4 1.6 8.6 18.4 1.1 1 0 0 1 1 1 0 SPX domain Apt1 PF10351.9 KXS18585.1 - 3.3 6.5 7.5 4.1 6.2 7.5 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain DNA_pol_phi PF04931.13 KXS18585.1 - 7.9 4.4 17.4 11 4.0 17.4 1.0 1 0 0 1 1 1 0 DNA polymerase phi Septin PF00735.18 KXS18586.1 - 1e-08 34.8 0.0 1.3e-08 34.5 0.0 1.1 1 0 0 1 1 1 1 Septin FtsK_SpoIIIE PF01580.18 KXS18586.1 - 4.3e-05 23.0 0.0 4.5e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 FtsK/SpoIIIE family T2SSE PF00437.20 KXS18586.1 - 0.0011 18.1 0.0 0.0011 18.1 0.0 1.1 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_7 PF12775.7 KXS18586.1 - 0.0019 17.7 0.0 0.0023 17.5 0.0 1.1 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_16 PF13191.6 KXS18586.1 - 0.002 18.5 0.0 0.0023 18.3 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.23 KXS18586.1 - 0.0023 18.0 0.1 0.0029 17.7 0.1 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase IIGP PF05049.13 KXS18586.1 - 0.0037 16.4 0.0 0.0044 16.1 0.0 1.1 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) Sigma54_activat PF00158.26 KXS18586.1 - 0.0038 17.0 0.0 0.0044 16.7 0.0 1.1 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_22 PF13401.6 KXS18586.1 - 0.013 15.8 0.0 0.017 15.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KXS18586.1 - 0.019 14.9 0.0 0.022 14.7 0.0 1.1 1 0 0 1 1 1 0 RsgA GTPase Roc PF08477.13 KXS18586.1 - 0.019 15.2 0.1 0.024 14.8 0.1 1.1 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 KXS18586.1 - 0.023 14.4 0.0 0.03 14.1 0.0 1.1 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KXS18586.1 - 0.036 14.0 0.0 0.05 13.5 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_29 PF13555.6 KXS18586.1 - 0.071 12.9 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain TsaE PF02367.17 KXS18586.1 - 0.094 12.7 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DEAD PF00270.29 KXS18586.1 - 0.094 12.5 0.0 0.11 12.3 0.0 1.1 1 0 0 1 1 1 0 DEAD/DEAH box helicase FeoB_N PF02421.18 KXS18586.1 - 0.1 12.1 0.1 0.13 11.8 0.1 1.1 1 0 0 1 1 1 0 Ferrous iron transport protein B Pox_A32 PF04665.12 KXS18586.1 - 0.15 11.5 0.0 0.18 11.3 0.0 1.1 1 0 0 1 1 1 0 Poxvirus A32 protein Septin PF00735.18 KXS18587.1 - 1.4e-68 231.3 0.0 3.3e-68 230.0 0.0 1.5 2 0 0 2 2 2 1 Septin DAP3 PF10236.9 KXS18588.1 - 9.3e-52 176.1 0.0 1.3e-51 175.7 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.6 KXS18588.1 - 0.00045 20.6 0.0 0.00074 19.9 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain NTPase_1 PF03266.15 KXS18588.1 - 0.17 11.8 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 NTPase ATPase_2 PF01637.18 KXS18588.1 - 0.21 11.4 0.0 0.43 10.4 0.0 1.6 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea B9-C2 PF07162.11 KXS18589.1 - 8.5e-34 117.2 0.0 1e-33 116.9 0.0 1.1 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein Plus-3 PF03126.18 KXS18590.1 - 3.8e-24 85.3 0.3 1.1e-23 83.9 0.0 2.0 2 0 0 2 2 2 1 Plus-3 domain YbaJ PF10757.9 KXS18590.1 - 0.22 12.1 1.5 2.2 8.9 0.0 3.0 3 0 0 3 3 3 0 Biofilm formation regulator YbaJ NOG1_N PF17835.1 KXS18591.1 - 9.4e-55 185.0 0.3 2.2e-54 183.7 0.3 1.7 1 0 0 1 1 1 1 NOG1 N-terminal helical domain NOG1 PF06858.14 KXS18591.1 - 1e-27 95.6 0.2 2.3e-27 94.5 0.2 1.6 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) NOGCT PF08155.11 KXS18591.1 - 3.1e-27 94.3 2.7 8.2e-27 93.0 2.7 1.8 1 0 0 1 1 1 1 NOGCT (NUC087) domain MMR_HSR1 PF01926.23 KXS18591.1 - 9.7e-19 67.5 0.0 2.2e-18 66.4 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KXS18591.1 - 9.7e-10 38.2 0.0 2e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B AIG1 PF04548.16 KXS18591.1 - 1.1e-05 24.8 0.5 0.1 11.9 0.0 3.0 3 0 0 3 3 3 2 AIG1 family Ras PF00071.22 KXS18591.1 - 0.00053 19.6 0.0 0.0011 18.6 0.0 1.5 1 0 0 1 1 1 1 Ras family Dynamin_N PF00350.23 KXS18591.1 - 0.0036 17.4 2.5 0.51 10.4 0.0 3.2 3 1 1 4 4 4 1 Dynamin family AAA_18 PF13238.6 KXS18591.1 - 0.013 16.0 0.2 1.9 9.1 0.0 3.4 3 0 0 3 3 3 0 AAA domain RsgA_GTPase PF03193.16 KXS18591.1 - 0.02 14.8 0.2 0.77 9.6 0.0 3.1 3 1 0 3 3 3 0 RsgA GTPase Roc PF08477.13 KXS18591.1 - 0.037 14.3 0.0 0.45 10.7 0.0 2.6 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KXS18591.1 - 0.054 12.9 1.5 0.14 11.6 0.0 2.5 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 KXS18591.1 - 0.072 13.5 0.0 0.63 10.4 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain SnoaL_2 PF12680.7 KXS18593.1 - 0.0022 18.6 0.1 1.7 9.3 0.0 2.4 2 0 0 2 2 2 2 SnoaL-like domain BTB PF00651.31 KXS18594.1 - 2e-06 28.0 0.0 8.5e-06 26.0 0.0 2.1 2 1 0 2 2 2 1 BTB/POZ domain Snf7 PF03357.21 KXS18595.1 - 8e-23 80.9 2.7 1.2e-22 80.4 2.7 1.2 1 0 0 1 1 1 1 Snf7 Cytochrom_B562 PF07361.11 KXS18595.1 - 0.0079 16.8 2.1 1.8 9.3 1.1 2.7 2 1 0 2 2 2 2 Cytochrome b562 LUC7 PF03194.15 KXS18595.1 - 1.1 8.8 8.1 2.1 8.0 8.0 1.4 1 1 0 1 1 1 0 LUC7 N_terminus Arf PF00025.21 KXS18596.1 - 1.1e-47 161.7 0.0 1.3e-47 161.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 KXS18596.1 - 3.5e-19 69.0 0.0 4e-19 68.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXS18596.1 - 4.6e-17 62.4 0.0 6.7e-17 61.8 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KXS18596.1 - 1.5e-11 44.0 0.0 1.8e-11 43.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KXS18596.1 - 4.6e-11 42.5 0.0 5.4e-11 42.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KXS18596.1 - 2.8e-08 33.8 0.0 3.9e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 KXS18596.1 - 1.4e-07 31.0 1.1 6.6e-05 22.2 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Dynamin_N PF00350.23 KXS18596.1 - 0.0052 16.9 0.0 0.72 9.9 0.1 2.2 1 1 1 2 2 2 1 Dynamin family AAA_7 PF12775.7 KXS18596.1 - 0.0073 15.8 0.0 0.0094 15.5 0.0 1.2 1 0 0 1 1 1 1 P-loop containing dynein motor region FeoB_N PF02421.18 KXS18596.1 - 0.0091 15.5 0.1 0.019 14.5 0.1 1.6 2 0 0 2 2 2 1 Ferrous iron transport protein B NACHT PF05729.12 KXS18596.1 - 0.014 15.3 0.0 0.21 11.5 0.0 2.1 1 1 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 KXS18596.1 - 0.044 14.3 0.0 0.062 13.8 0.0 1.5 1 1 0 1 1 1 0 ABC transporter ATP_bind_1 PF03029.17 KXS18596.1 - 0.11 12.3 0.0 6.4 6.5 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein cobW PF02492.19 KXS18596.1 - 0.11 12.1 0.0 2.5 7.7 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.29 KXS18596.1 - 0.15 12.4 0.0 0.23 11.9 0.0 1.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) CBF PF03914.17 KXS18598.1 - 1.9e-37 128.9 0.2 2.2e-37 128.7 0.2 1.1 1 0 0 1 1 1 1 CBF/Mak21 family NAD_binding_10 PF13460.6 KXS18599.1 - 2.9e-13 50.1 0.0 4.6e-13 49.5 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding FAD_binding_3 PF01494.19 KXS18599.1 - 0.022 14.0 0.1 0.032 13.5 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain NmrA PF05368.13 KXS18599.1 - 0.051 13.1 0.0 0.072 12.6 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family Epimerase PF01370.21 KXS18599.1 - 0.11 11.9 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family RIX1 PF08167.12 KXS18600.1 - 4.1e-22 78.8 0.1 1e-21 77.6 0.1 1.7 1 0 0 1 1 1 1 rRNA processing/ribosome biogenesis Ribosomal_L37 PF08561.10 KXS18601.1 - 3e-16 60.0 0.1 4e-16 59.6 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L37 ribosomal_L24 PF17136.4 KXS18602.1 - 1.4e-10 41.4 0.0 2.6e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 Ribosomal proteins 50S L24/mitochondrial 39S L24 KOW PF00467.29 KXS18602.1 - 5.8e-06 26.1 0.0 1.1e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 KOW motif BTB PF00651.31 KXS18603.1 - 2.5e-07 30.9 0.0 1.9e-06 28.1 0.0 2.4 2 0 0 2 2 2 1 BTB/POZ domain WD40 PF00400.32 KXS18604.1 - 2.2e-43 145.4 29.7 1.4e-07 32.1 0.0 8.2 8 0 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXS18604.1 - 4.9e-19 68.4 0.0 0.0046 17.2 0.0 5.9 1 1 4 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KXS18604.1 - 2.9e-08 33.8 0.0 0.002 18.0 0.0 2.5 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KXS18604.1 - 1.7e-07 30.9 0.0 0.00064 19.1 0.0 2.4 2 0 0 2 2 2 2 WD40-like domain Ge1_WD40 PF16529.5 KXS18604.1 - 1.3e-06 27.6 4.7 0.0039 16.2 0.0 4.6 2 1 1 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KXS18604.1 - 0.0011 17.8 2.5 7.1 5.1 0.3 4.0 2 2 2 4 4 4 3 Nucleoporin Nup120/160 Frtz PF11768.8 KXS18604.1 - 0.011 14.1 0.0 5.2 5.3 0.0 2.9 2 1 1 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz RRM_1 PF00076.22 KXS18605.1 - 2.5e-32 110.5 0.1 2.1e-11 43.5 0.0 4.1 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KXS18605.1 - 9.1e-05 22.5 0.0 0.008 16.3 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif RRM_9 PF18444.1 KXS18605.1 - 0.0026 17.6 0.0 0.019 14.8 0.0 2.4 2 1 0 2 2 2 1 RNA recognition motif RRM_occluded PF16842.5 KXS18605.1 - 0.004 17.0 0.0 0.45 10.4 0.0 2.7 2 0 0 2 2 2 1 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 KXS18605.1 - 0.099 12.7 0.0 23 5.1 0.0 3.3 4 0 0 4 4 4 0 Nup53/35/40-type RNA recognition motif SIL1 PF16782.5 KXS18606.1 - 9.2e-06 25.1 0.0 1.3e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 Nucleotide exchange factor SIL1 GCIP PF13324.6 KXS18607.1 - 2e-13 50.6 1.9 2.5e-13 50.2 1.9 1.2 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting TMEM164 PF14808.6 KXS18608.1 - 9.5e-24 84.1 9.7 1.2e-23 83.8 9.7 1.1 1 0 0 1 1 1 1 TMEM164 family Snf7 PF03357.21 KXS18609.1 - 2e-28 99.2 4.2 2.4e-28 98.9 4.2 1.0 1 0 0 1 1 1 1 Snf7 Pox_G7 PF05503.12 KXS18609.1 - 0.011 14.7 0.0 0.016 14.2 0.0 1.3 1 0 0 1 1 1 0 Poxvirus G7-like FAM76 PF16046.5 KXS18609.1 - 1.1 8.6 3.5 1.4 8.2 3.5 1.1 1 0 0 1 1 1 0 FAM76 protein YlqD PF11068.8 KXS18609.1 - 8.7 6.7 10.3 4.4 7.7 1.2 2.2 1 1 1 2 2 2 0 YlqD protein DUF4272 PF14094.6 KXS18610.1 - 0.019 14.2 0.0 0.021 14.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4272) KorB PF08535.10 KXS18610.1 - 0.025 14.6 0.1 0.036 14.1 0.1 1.4 1 1 0 1 1 1 0 KorB domain Glyco_hydro_70 PF02324.16 KXS18610.1 - 0.054 11.7 0.0 0.06 11.5 0.0 1.0 1 0 0 1 1 1 0 Glycosyl hydrolase family 70 Vezatin PF12632.7 KXS18611.1 - 0.053 12.9 0.1 0.096 12.0 0.1 1.3 1 0 0 1 1 1 0 Mysoin-binding motif of peroxisomes MFS_1 PF07690.16 KXS18613.1 - 5.5e-48 163.7 41.6 1e-47 162.8 41.6 1.5 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KXS18613.1 - 4.6e-21 74.9 21.6 6e-21 74.5 21.6 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KXS18613.1 - 3.5e-12 45.9 8.8 3.5e-12 45.9 8.8 2.9 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.7 KXS18613.1 - 3.5e-05 22.8 4.6 3.5e-05 22.8 4.6 2.5 2 0 0 2 2 2 1 MFS_1 like family LacY_symp PF01306.19 KXS18613.1 - 0.24 10.1 12.4 0.53 9.0 4.6 2.5 2 1 0 2 2 2 0 LacY proton/sugar symporter OATP PF03137.20 KXS18613.1 - 0.33 9.2 9.8 0.023 13.0 1.2 2.4 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Glyco_hydro_114 PF03537.13 KXS18615.1 - 3e-49 167.4 0.0 3.3e-49 167.3 0.0 1.0 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 Acetate_kinase PF00871.17 KXS18617.1 - 8.2e-27 93.9 2.5 3e-14 52.5 0.0 3.1 2 1 0 2 2 2 2 Acetokinase family zf-NADH-PPase PF09297.11 KXS18617.1 - 2.6 7.8 6.7 0.34 10.6 0.7 2.8 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain zf-C2H2_10 PF16588.5 KXS18618.1 - 0.1 12.4 2.5 0.26 11.0 2.5 1.7 1 0 0 1 1 1 0 C2H2 zinc-finger GYF_2 PF14237.6 KXS18619.1 - 0.014 15.2 0.1 0.037 13.8 0.0 1.7 2 0 0 2 2 2 0 GYF domain 2 DUF3552 PF12072.8 KXS18621.1 - 0.18 11.2 2.3 0.26 10.7 2.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DLP_helical PF18709.1 KXS18621.1 - 0.2 10.8 0.2 0.24 10.6 0.2 1.1 1 0 0 1 1 1 0 Dynamin-like helical domain Brix PF04427.18 KXS18622.1 - 8.3e-29 101.1 0.0 1.4e-28 100.3 0.0 1.3 1 0 0 1 1 1 1 Brix domain TnsD PF15978.5 KXS18622.1 - 0.056 12.4 0.1 0.089 11.8 0.1 1.2 1 0 0 1 1 1 0 Tn7-like transposition protein D MCPVI PF02993.14 KXS18624.1 - 1 9.1 3.6 1.1 9.1 3.6 1.1 1 0 0 1 1 1 0 Minor capsid protein VI Cnd3 PF12719.7 KXS18626.1 - 2e-61 207.8 0.5 1.8e-60 204.6 0.1 2.7 3 0 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 KXS18626.1 - 1.4e-06 28.6 5.3 0.015 15.6 0.1 5.5 4 2 1 5 5 5 3 HEAT repeats Cohesin_HEAT PF12765.7 KXS18626.1 - 0.01 16.1 2.8 8.9 6.7 0.1 3.9 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion Spt20 PF12090.8 KXS18627.1 - 2.6e-14 53.4 0.0 1.9e-09 37.5 0.0 2.2 1 1 0 2 2 2 2 Spt20 family MOZ_SAS PF01853.18 KXS18628.1 - 2.9e-80 268.1 0.0 3.8e-80 267.8 0.0 1.1 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 KXS18628.1 - 4.3e-22 77.5 0.6 4.3e-22 77.5 0.6 1.8 2 0 0 2 2 2 1 MYST family zinc finger domain Ribosomal_S19e PF01090.19 KXS18629.1 - 7.8e-58 194.0 0.2 8.7e-58 193.9 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e TFA2_Winged_2 PF18121.1 KXS18630.1 - 3.1e-16 58.8 0.2 5.4e-16 58.0 0.2 1.4 1 0 0 1 1 1 1 TFA2 Winged helix domain 2 TFIIE_beta PF02186.15 KXS18630.1 - 2.1e-08 34.3 1.6 2.6e-08 34.0 0.3 1.9 2 0 0 2 2 2 1 TFIIE beta subunit core domain ANAPC_CDC26 PF10471.9 KXS18630.1 - 0.016 16.0 3.4 0.038 14.8 3.4 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit CDC26 Topoisom_bac PF01131.20 KXS18631.1 - 2.7e-106 356.1 0.0 3.4e-106 355.7 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase zf-GRF PF06839.12 KXS18631.1 - 2.8e-26 91.4 23.3 7.9e-15 54.7 3.1 3.3 3 0 0 3 3 3 2 GRF zinc finger Toprim PF01751.22 KXS18631.1 - 2.1e-16 60.0 0.0 3.7e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 Toprim domain zf-C4_Topoisom PF01396.19 KXS18631.1 - 1e-07 31.6 0.6 1e-07 31.6 0.6 2.9 2 0 0 2 2 2 1 Topoisomerase DNA binding C4 zinc finger MSA-2c PF12238.8 KXS18631.1 - 1.9 8.4 4.2 4.4 7.3 4.2 1.5 1 0 0 1 1 1 0 Merozoite surface antigen 2c Clat_adaptor_s PF01217.20 KXS18632.1 - 7.6e-53 178.3 0.6 8.8e-53 178.1 0.6 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Ras PF00071.22 KXS18633.1 - 3.1e-54 182.9 0.0 3.6e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXS18633.1 - 3.7e-22 78.8 0.0 5e-22 78.4 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXS18633.1 - 1.8e-07 30.8 0.0 2.3e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KXS18633.1 - 0.0099 15.4 0.0 0.041 13.4 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain UPRTase PF14681.6 KXS18634.1 - 2.2e-68 229.8 0.0 2.4e-68 229.6 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 KXS18634.1 - 0.00023 20.7 0.1 0.00044 19.8 0.1 1.5 1 1 0 1 1 1 1 Phosphoribosyl transferase domain DUF3263 PF11662.8 KXS18634.1 - 0.037 13.9 0.5 1.3 8.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3263) GTP_CH_N PF12471.8 KXS18635.1 - 8.9e-85 283.3 0.0 1.5e-84 282.5 0.0 1.4 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.20 KXS18635.1 - 4e-16 59.0 0.0 6.1e-16 58.4 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase II Ank_2 PF12796.7 KXS18636.1 - 1.6e-09 38.2 0.4 4.3e-07 30.4 0.2 2.4 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KXS18636.1 - 1.2e-08 35.0 0.5 0.00048 20.4 0.0 3.0 2 1 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 KXS18636.1 - 2.2e-07 30.6 0.3 0.0043 17.5 0.0 3.7 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 KXS18636.1 - 1.9e-06 28.0 1.5 9.2e-06 25.8 0.5 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXS18636.1 - 1.3e-05 25.6 0.8 0.007 16.9 0.1 3.3 2 1 1 3 3 3 1 Ankyrin repeats (many copies) DUF1117 PF06547.12 KXS18636.1 - 0.15 12.7 1.7 3.5 8.2 0.3 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1117) Ank_4 PF13637.6 KXS18637.1 - 0.0029 18.2 0.0 0.0039 17.7 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXS18637.1 - 0.035 14.7 0.0 0.042 14.4 0.0 1.1 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXS18637.1 - 0.035 14.4 0.0 0.055 13.8 0.0 1.4 1 0 0 1 1 1 0 Ankyrin repeats (many copies) F-box-like PF12937.7 KXS18638.1 - 1.5e-05 24.8 0.1 4.4e-05 23.3 0.1 1.8 1 0 0 1 1 1 1 F-box-like TPR_2 PF07719.17 KXS18638.1 - 0.0018 18.2 0.3 0.0041 17.1 0.3 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 KXS18638.1 - 0.0031 17.3 0.2 0.0058 16.4 0.2 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.6 KXS18638.1 - 0.027 14.8 1.2 0.061 13.6 1.2 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 KXS18638.1 - 0.031 15.1 0.7 0.11 13.3 0.7 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_7 PF13176.6 KXS18638.1 - 0.073 13.1 0.1 0.25 11.5 0.1 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat MIT PF04212.18 KXS18638.1 - 0.13 12.4 0.5 0.26 11.4 0.5 1.5 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain TauD PF02668.16 KXS18639.1 - 3.1e-51 174.8 0.3 4.2e-51 174.3 0.3 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 KXS18639.1 - 1.2e-11 45.1 0.1 3.4e-11 43.6 0.1 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF971) CsiD PF08943.10 KXS18639.1 - 0.14 11.2 0.0 0.24 10.5 0.0 1.2 1 0 0 1 1 1 0 CsiD ICL PF00463.21 KXS18640.1 - 5.5e-262 869.9 2.0 6.3e-262 869.7 2.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family Arg_repressor_C PF02863.18 KXS18640.1 - 0.0049 16.7 0.0 0.025 14.4 0.0 2.1 2 0 0 2 2 2 1 Arginine repressor, C-terminal domain Cir_N PF10197.9 KXS18641.1 - 6.4e-06 26.3 11.9 6.4e-06 26.3 11.9 3.2 3 0 0 3 3 3 1 N-terminal domain of CBF1 interacting co-repressor CIR Vta1 PF04652.16 KXS18642.1 - 9.6e-49 165.1 1.7 1.3e-48 164.7 1.7 1.1 1 0 0 1 1 1 1 Vta1 like Vta1_C PF18097.1 KXS18642.1 - 1.9e-16 59.5 0.7 3.7e-16 58.5 0.7 1.5 1 0 0 1 1 1 1 Vta1 C-terminal domain OSCP PF00213.18 KXS18643.1 - 1.9e-45 155.1 0.9 2.2e-45 154.8 0.9 1.1 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit LRR_8 PF13855.6 KXS18644.1 - 6.5e-06 25.8 0.3 1e-05 25.2 0.3 1.2 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 KXS18644.1 - 0.00028 21.2 0.1 0.00052 20.3 0.1 1.5 1 0 0 1 1 1 1 Leucine Rich repeats (2 copies) FokI_N PF02981.15 KXS18644.1 - 0.1 12.8 0.1 0.17 12.1 0.1 1.3 1 0 0 1 1 1 0 Restriction endonuclease FokI, recognition domain Mannosyl_trans3 PF11051.8 KXS18645.1 - 4.9e-38 131.1 0.0 6.5e-38 130.7 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative DUF563 PF04577.14 KXS18646.1 - 4.6e-21 75.9 0.2 1.8e-20 74.0 0.2 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF563) Amidase PF01425.21 KXS18647.1 - 9.3e-44 150.1 3.2 1.2e-18 67.3 0.0 4.0 3 1 1 4 4 4 4 Amidase LRR_8 PF13855.6 KXS18648.1 - 1.8e-15 56.5 9.4 2.8e-07 30.2 2.2 3.7 1 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 KXS18648.1 - 2.4e-12 46.9 13.8 0.00012 22.4 0.8 5.1 1 1 4 6 6 6 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KXS18648.1 - 7.9e-08 31.8 9.5 5.2 8.0 0.1 7.1 6 1 0 6 6 6 3 Leucine Rich Repeat LRR_6 PF13516.6 KXS18648.1 - 0.00027 20.7 12.1 1.5 9.0 0.1 5.8 6 0 0 6 6 6 3 Leucine Rich repeat FAD_binding_3 PF01494.19 KXS18649.1 - 1.9e-21 76.7 0.0 1.6e-10 40.7 0.0 3.1 3 0 0 3 3 3 3 FAD binding domain Lycopene_cycl PF05834.12 KXS18649.1 - 1.2e-06 27.8 0.4 0.0041 16.2 0.1 3.1 3 0 0 3 3 3 2 Lycopene cyclase protein DAO PF01266.24 KXS18649.1 - 9e-05 22.2 0.0 0.00018 21.2 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase SE PF08491.10 KXS18649.1 - 0.00034 19.8 0.0 0.00061 18.9 0.0 1.4 1 0 0 1 1 1 1 Squalene epoxidase Pyr_redox_2 PF07992.14 KXS18649.1 - 0.00041 19.7 0.0 0.0022 17.3 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KXS18649.1 - 0.00078 18.4 0.0 0.0089 14.9 0.0 2.4 3 0 0 3 3 3 1 Tryptophan halogenase NAD_binding_8 PF13450.6 KXS18649.1 - 0.017 15.3 0.6 0.049 13.9 0.6 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KXS18649.1 - 0.03 14.3 0.0 0.069 13.1 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding Thi4 PF01946.17 KXS18649.1 - 0.076 12.3 0.1 0.16 11.2 0.1 1.4 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.24 KXS18649.1 - 0.27 10.3 2.9 0.53 9.3 2.9 1.5 1 0 0 1 1 1 0 FAD binding domain PCI PF01399.27 KXS18650.1 - 1.6e-23 83.2 2.8 1.6e-23 83.2 2.8 2.2 2 0 0 2 2 2 1 PCI domain DUF4404 PF14357.6 KXS18650.1 - 0.041 14.5 0.3 0.17 12.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) DUF4882 PF16223.5 KXS18650.1 - 0.043 13.0 0.8 0.22 10.7 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4882) Ank PF00023.30 KXS18651.1 - 1.3e-06 28.5 0.0 2.9e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeat Ank_3 PF13606.6 KXS18651.1 - 1.8e-06 27.8 0.0 3.8e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeat Ank_5 PF13857.6 KXS18651.1 - 3e-05 24.2 0.0 6.3e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXS18651.1 - 9.5e-05 22.9 0.0 0.0002 21.9 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXS18651.1 - 0.00014 22.3 0.0 0.00035 21.1 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) PCI PF01399.27 KXS18653.1 - 8.2e-23 80.9 4.3 1e-21 77.4 0.0 3.3 2 1 0 2 2 2 1 PCI domain RPN5_C PF18098.1 KXS18653.1 - 2.4e-13 49.9 4.3 5.8e-13 48.7 2.7 2.4 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN5 C-terminal domain Elf4 PF07011.11 KXS18653.1 - 0.07 13.0 1.5 19 5.2 0.1 3.5 3 0 0 3 3 3 0 Early Flowering 4 domain ERp29 PF07749.12 KXS18653.1 - 1.2 10.1 5.2 2.8 8.9 0.2 3.6 2 2 1 3 3 3 0 Endoplasmic reticulum protein ERp29, C-terminal domain RRM_1 PF00076.22 KXS18654.1 - 3.9e-17 61.8 0.0 2.1e-08 33.8 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G-patch PF01585.23 KXS18654.1 - 1.1e-16 60.5 1.2 2.5e-16 59.3 1.2 1.7 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KXS18654.1 - 0.0001 22.3 0.1 0.0001 22.3 0.1 1.9 2 0 0 2 2 2 1 G-patch domain zf-C2H2_jaz PF12171.8 KXS18654.1 - 0.067 13.5 0.1 0.14 12.5 0.1 1.4 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding NapB PF03892.14 KXS18654.1 - 0.12 12.4 0.9 0.35 10.9 0.9 1.8 1 0 0 1 1 1 0 Nitrate reductase cytochrome c-type subunit (NapB) OTT_1508_deam PF14441.6 KXS18654.1 - 0.13 12.3 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 OTT_1508-like deaminase zf-C2H2_2 PF12756.7 KXS18654.1 - 0.14 12.5 0.6 0.33 11.3 0.6 1.6 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) PRAS PF15798.5 KXS18654.1 - 1.5 9.4 4.2 1.3 9.6 0.2 2.3 2 0 0 2 2 2 0 Proline-rich AKT1 substrate 1 Paf1 PF03985.13 KXS18655.1 - 4.5e-54 184.1 0.0 5.3e-54 183.8 0.0 1.1 1 0 0 1 1 1 1 Paf1 Choline_kinase PF01633.20 KXS18656.1 - 1.3e-55 188.3 0.0 4.4e-55 186.6 0.0 1.7 1 1 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 KXS18656.1 - 2.8e-08 34.0 4.8 5.8e-08 33.0 0.6 2.9 1 1 2 3 3 3 1 Phosphotransferase enzyme family Pox_vIL-18BP PF05566.12 KXS18657.1 - 0.043 14.0 0.0 0.074 13.3 0.0 1.3 1 0 0 1 1 1 0 Orthopoxvirus interleukin 18 binding protein K_trans PF02705.16 KXS18658.1 - 6.4e-190 632.2 9.9 6.8e-177 589.2 13.2 2.0 2 0 0 2 2 2 2 K+ potassium transporter MFS_1 PF07690.16 KXS18659.1 - 9.2e-20 70.9 25.6 1.4e-19 70.3 25.6 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Formyl_trans_N PF00551.19 KXS18660.1 - 2.5e-25 89.3 0.0 3.8e-25 88.7 0.0 1.4 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.18 KXS18660.1 - 2.5e-14 53.3 0.0 7.5e-14 51.8 0.0 1.8 2 0 0 2 2 2 1 Formyl transferase, C-terminal domain MFS_1 PF07690.16 KXS18661.1 - 2.8e-23 82.4 28.0 4.1e-23 81.9 28.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Peptidase_M28 PF04389.17 KXS18663.1 - 1.4e-32 113.0 0.1 1.9e-32 112.5 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KXS18663.1 - 0.00038 20.2 0.0 0.00074 19.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 DUF2062 PF09835.9 KXS18663.1 - 0.0028 17.5 3.0 0.0028 17.5 3.0 2.9 3 1 0 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2062) ANAPC4_WD40 PF12894.7 KXS18664.1 - 1.1e-06 28.9 0.0 0.14 12.5 0.0 4.3 4 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KXS18664.1 - 0.3 12.0 21.3 6.2 7.9 0.0 6.4 6 1 1 7 7 7 0 WD domain, G-beta repeat Beach PF02138.18 KXS18665.1 - 2.7e-39 135.2 0.0 4.3e-39 134.6 0.0 1.3 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 KXS18665.1 - 1.2e-22 79.9 0.0 2.6e-22 78.8 0.0 1.6 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH WD40 PF00400.32 KXS18666.1 - 5.9e-11 42.7 6.0 8e-05 23.3 0.5 3.3 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXS18666.1 - 2.6e-05 24.4 0.7 0.026 14.8 0.0 3.7 1 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Med12 PF09497.10 KXS18667.1 - 5.4e-21 74.7 0.9 3.8e-20 72.0 0.1 2.7 3 1 0 3 3 3 1 Transcription mediator complex subunit Med12 DUF4471 PF14740.6 KXS18668.1 - 6.4e-85 285.1 6.1 2.1e-68 230.8 3.2 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4471) DUF4470 PF14737.6 KXS18668.1 - 5.6e-21 74.6 0.0 1.1e-20 73.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) GrpB PF04229.14 KXS18668.1 - 0.056 13.6 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 GrpB protein Raptor_N PF14538.6 KXS18669.1 - 1.6e-69 232.5 0.0 2.8e-69 231.7 0.0 1.4 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain Cnd1 PF12717.7 KXS18669.1 - 8.3e-06 25.9 0.0 0.0023 18.0 0.0 2.8 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KXS18669.1 - 1.1e-05 25.3 7.5 0.031 14.5 0.0 5.4 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.6 KXS18669.1 - 1.9e-05 25.0 0.4 0.079 13.4 0.1 3.7 3 0 0 3 3 3 2 HEAT repeats ANAPC4_WD40 PF12894.7 KXS18669.1 - 6.4e-05 23.2 0.5 2.1 8.7 0.0 4.8 1 1 3 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KXS18669.1 - 0.00095 19.9 10.7 8.8 7.4 0.2 6.9 7 1 0 7 7 7 1 WD domain, G-beta repeat BBS2_Mid PF14783.6 KXS18669.1 - 0.019 15.0 0.2 8.4 6.5 0.0 3.8 2 1 2 4 4 4 0 Ciliary BBSome complex subunit 2, middle region HEAT_EZ PF13513.6 KXS18669.1 - 0.088 13.3 0.5 32 5.2 0.1 3.3 3 0 0 3 3 3 0 HEAT-like repeat Rcd1 PF04078.13 KXS18669.1 - 0.11 11.7 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Cell differentiation family, Rcd1-like Atx10homo_assoc PF09759.9 KXS18669.1 - 0.13 12.3 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Spinocerebellar ataxia type 10 protein domain Ku PF02735.16 KXS18670.1 - 1.7e-42 145.5 0.0 2.9e-42 144.7 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 KXS18670.1 - 2.5e-17 63.4 0.0 8.1e-17 61.7 0.0 1.8 2 0 0 2 2 2 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 KXS18670.1 - 6.7e-14 52.3 4.6 6.8e-14 52.3 0.4 2.8 3 0 0 3 3 3 1 Ku70/Ku80 C-terminal arm zf-RING_2 PF13639.6 KXS18671.1 - 2.8e-10 40.4 6.4 2.8e-10 40.4 6.4 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 KXS18671.1 - 1.5e-09 37.6 9.8 3.6e-09 36.3 6.5 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) ubiquitin PF00240.23 KXS18671.1 - 1.9e-09 37.1 0.0 0.002 17.8 0.0 3.4 3 0 0 3 3 3 2 Ubiquitin family zf-rbx1 PF12678.7 KXS18671.1 - 3.4e-07 30.5 8.5 1.3e-06 28.5 8.5 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KXS18671.1 - 7.7e-07 28.9 6.9 7.7e-07 28.9 6.9 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXS18671.1 - 1.4e-06 28.2 2.9 3.2e-06 27.1 2.9 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KXS18671.1 - 4.3e-06 26.5 3.6 4.3e-06 26.5 3.6 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KXS18671.1 - 5.6e-06 26.0 2.0 5.6e-06 26.0 2.0 2.0 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_5 PF14634.6 KXS18671.1 - 0.00076 19.4 5.2 0.00076 19.4 5.2 2.5 2 1 1 3 3 3 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 KXS18671.1 - 0.0021 18.1 1.2 0.0021 18.1 1.2 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger DUF3261 PF11659.8 KXS18671.1 - 0.019 14.8 0.0 1.1 9.1 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3261) Zn_ribbon_17 PF17120.5 KXS18671.1 - 0.02 14.5 3.0 0.02 14.5 3.0 2.2 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 KXS18671.1 - 0.028 14.3 4.0 0.072 13.0 4.0 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf_Rg PF17915.1 KXS18671.1 - 0.035 13.5 0.5 1.3 8.4 0.1 2.7 2 0 0 2 2 2 0 Reverse gyrase zinc finger zf-RING_10 PF16685.5 KXS18671.1 - 0.49 10.6 4.6 1.4 9.1 4.6 1.8 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-C3H2C3 PF17122.5 KXS18671.1 - 0.71 10.0 7.7 0.19 11.8 3.4 2.2 2 0 0 2 2 2 0 Zinc-finger PHD PF00628.29 KXS18671.1 - 2.6 8.0 8.6 2.8 7.9 4.5 2.5 2 0 0 2 2 2 0 PHD-finger PI3K_P85_iSH2 PF16454.5 KXS18675.1 - 0.011 15.4 10.2 0.32 10.6 1.8 2.2 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain JIP_LZII PF16471.5 KXS18675.1 - 0.016 15.4 1.6 0.036 14.2 1.1 1.9 1 1 0 1 1 1 0 JNK-interacting protein leucine zipper II V-ATPase_G PF03179.15 KXS18675.1 - 0.28 11.7 6.0 0.7 10.5 6.0 1.7 1 1 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit AAA_13 PF13166.6 KXS18676.1 - 0.18 10.4 0.1 0.25 10.0 0.1 1.1 1 0 0 1 1 1 0 AAA domain Macoilin PF09726.9 KXS18676.1 - 0.2 10.2 2.9 0.3 9.6 2.9 1.2 1 0 0 1 1 1 0 Macoilin family MA3 PF02847.17 KXS18677.1 - 2.6e-24 85.4 0.6 1.5e-23 83.0 0.2 2.2 2 0 0 2 2 2 1 MA3 domain MIF4G PF02854.19 KXS18677.1 - 4.4e-14 52.6 0.0 1.1e-13 51.3 0.0 1.7 2 0 0 2 2 2 1 MIF4G domain IMD PF08397.11 KXS18677.1 - 0.089 12.2 2.2 0.27 10.6 0.0 2.1 2 0 0 2 2 2 0 IRSp53/MIM homology domain Nop14 PF04147.12 KXS18677.1 - 0.15 10.2 19.8 0.26 9.5 19.8 1.3 1 0 0 1 1 1 0 Nop14-like family ATG16 PF08614.11 KXS18679.1 - 0.0024 18.1 9.5 0.0039 17.4 9.5 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Lebercilin PF15619.6 KXS18679.1 - 0.0044 16.7 6.6 0.0075 16.0 6.6 1.3 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease APG6_N PF17675.1 KXS18679.1 - 0.0064 17.0 6.6 0.013 16.1 6.6 1.4 1 0 0 1 1 1 1 Apg6 coiled-coil region DUF4201 PF13870.6 KXS18679.1 - 0.0073 16.1 2.3 0.01 15.6 2.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) Spc7 PF08317.11 KXS18679.1 - 0.013 14.4 6.5 0.02 13.8 6.5 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF3584 PF12128.8 KXS18679.1 - 0.02 12.5 1.4 0.026 12.1 1.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) SPX PF03105.19 KXS18679.1 - 0.021 14.7 0.1 0.032 14.2 0.1 1.4 1 0 0 1 1 1 0 SPX domain DUF842 PF05811.13 KXS18679.1 - 0.038 13.7 0.6 0.059 13.1 0.6 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) Exonuc_VII_L PF02601.15 KXS18679.1 - 0.051 13.1 1.4 0.074 12.6 1.4 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Filament PF00038.21 KXS18679.1 - 0.053 13.1 4.9 0.075 12.6 4.9 1.1 1 0 0 1 1 1 0 Intermediate filament protein Fez1 PF06818.15 KXS18679.1 - 0.077 13.4 3.9 0.12 12.8 3.9 1.2 1 0 0 1 1 1 0 Fez1 TMF_TATA_bd PF12325.8 KXS18679.1 - 0.1 12.8 9.3 0.093 12.9 4.1 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF3545 PF12065.8 KXS18679.1 - 0.11 12.5 3.7 0.072 13.1 1.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3545) CENP-F_leu_zip PF10473.9 KXS18679.1 - 0.21 11.6 8.8 0.32 11.0 8.8 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ADIP PF11559.8 KXS18679.1 - 0.22 11.6 11.3 0.39 10.8 11.3 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF1640 PF07798.11 KXS18679.1 - 0.24 11.5 4.2 0.4 10.7 4.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) UPF0242 PF06785.11 KXS18679.1 - 0.26 11.4 2.7 0.39 10.8 2.7 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Atg14 PF10186.9 KXS18679.1 - 0.29 10.2 4.3 0.46 9.5 4.3 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 FUSC PF04632.12 KXS18679.1 - 0.33 9.5 1.6 0.46 9.0 1.6 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family kleA_kleC PF17383.2 KXS18679.1 - 1.5 9.2 9.4 0.59 10.5 0.5 2.4 1 1 1 2 2 2 0 Uncharacterized KorC regulated protein A TMPIT PF07851.13 KXS18679.1 - 2.4 7.3 3.6 3.3 6.9 3.6 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF3450 PF11932.8 KXS18679.1 - 2.6 7.3 7.7 4.8 6.4 7.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) CENP-H PF05837.12 KXS18679.1 - 9.1 6.7 10.4 21 5.6 10.4 1.6 1 1 0 1 1 1 0 Centromere protein H (CENP-H) WGG PF10273.9 KXS18681.1 - 8.7e-13 48.7 0.3 2.1e-12 47.5 0.0 1.7 2 0 0 2 2 2 1 Pre-rRNA-processing protein TSR2 Anoctamin PF04547.12 KXS18683.1 - 4.3e-65 220.3 0.7 5.4e-65 220.0 0.7 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Abhydrolase_2 PF02230.16 KXS18684.1 - 2.7e-13 50.2 0.0 4.4e-06 26.7 0.0 2.3 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 KXS18684.1 - 0.0031 16.8 0.0 0.3 10.3 0.0 3.1 3 1 1 4 4 4 1 Serine aminopeptidase, S33 Esterase PF00756.20 KXS18684.1 - 0.0034 17.1 0.0 0.0078 15.9 0.0 1.6 1 1 0 1 1 1 1 Putative esterase FSH1 PF03959.13 KXS18684.1 - 0.0092 15.7 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.20 KXS18684.1 - 0.1 12.2 0.0 1.6 8.3 0.0 2.7 3 0 0 3 3 3 0 alpha/beta hydrolase fold zf-RING_2 PF13639.6 KXS18685.1 - 2.1e-11 44.0 6.7 4.2e-11 43.0 6.7 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KXS18685.1 - 4.8e-10 39.0 1.5 8.8e-10 38.2 1.5 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KXS18685.1 - 2.3e-08 33.7 6.2 4e-08 33.0 6.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXS18685.1 - 9e-08 31.9 3.8 1.4e-07 31.3 3.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KXS18685.1 - 1.5e-05 25.1 7.2 3.9e-05 23.8 7.2 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 KXS18685.1 - 3.3e-05 23.6 2.6 5.4e-05 23.0 2.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXS18685.1 - 0.00013 21.9 2.9 0.00022 21.1 2.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 KXS18685.1 - 0.0005 20.1 1.5 0.00095 19.2 1.5 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 KXS18685.1 - 0.00062 19.7 2.2 0.00062 19.7 2.2 1.8 1 1 1 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KXS18685.1 - 0.0075 16.1 7.0 0.42 10.5 7.6 2.3 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 KXS18685.1 - 0.046 13.5 4.5 0.087 12.6 4.5 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.29 KXS18685.1 - 0.069 13.1 4.2 0.12 12.2 4.2 1.5 1 0 0 1 1 1 0 PHD-finger RINGv PF12906.7 KXS18685.1 - 0.14 12.3 2.0 0.3 11.3 2.0 1.6 1 1 0 1 1 1 0 RING-variant domain FANCL_C PF11793.8 KXS18685.1 - 0.22 11.7 3.7 0.98 9.6 3.7 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.6 KXS18685.1 - 0.42 10.8 3.1 0.93 9.7 3.1 1.6 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Zn_ribbon_17 PF17120.5 KXS18685.1 - 0.85 9.3 4.2 1.6 8.4 4.2 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Prok-RING_1 PF14446.6 KXS18685.1 - 1 9.4 5.5 0.29 11.1 1.1 2.0 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 Rad50_zn_hook PF04423.14 KXS18685.1 - 1.6 8.6 6.9 11 6.0 0.1 2.9 3 0 0 3 3 3 0 Rad50 zinc hook motif zf-RING-like PF08746.11 KXS18685.1 - 2.5 8.5 6.3 5.7 7.3 6.5 1.5 1 1 0 1 1 1 0 RING-like domain zf-C3H2C3 PF17122.5 KXS18685.1 - 6.4 6.9 12.9 25 5.0 0.3 2.6 2 1 0 2 2 2 0 Zinc-finger Lectin_leg-like PF03388.13 KXS18686.1 - 1.5e-70 237.2 0.0 2.1e-70 236.7 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family Bact_lectin PF18483.1 KXS18686.1 - 1.4e-08 35.0 0.3 1.9e-08 34.5 0.3 1.1 1 0 0 1 1 1 1 Bacterial lectin Lectin_legB PF00139.19 KXS18686.1 - 5.2e-07 29.5 0.0 3.2e-05 23.6 0.0 2.1 1 1 0 1 1 1 1 Legume lectin domain WD40 PF00400.32 KXS18687.1 - 1.9e-16 60.2 16.2 3.5e-05 24.5 0.1 7.2 9 0 0 9 9 9 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXS18687.1 - 0.0001 22.6 0.1 2.7 8.4 0.0 4.5 3 2 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KXS18687.1 - 0.017 13.8 1.5 0.36 9.4 0.1 2.2 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Fil_haemagg PF05594.14 KXS18687.1 - 0.036 14.6 0.4 0.036 14.6 0.4 2.3 2 0 0 2 2 2 0 Haemagluttinin repeat PQQ_3 PF13570.6 KXS18687.1 - 1.6 9.3 8.7 8.2 7.1 0.0 4.6 5 0 0 5 5 5 0 PQQ-like domain TBCC PF07986.12 KXS18688.1 - 2.8e-18 65.8 0.9 5e-18 65.0 0.9 1.4 1 0 0 1 1 1 1 Tubulin binding cofactor C TBCC_N PF16752.5 KXS18688.1 - 1.6e-14 54.3 0.0 3.1e-14 53.4 0.0 1.4 1 0 0 1 1 1 1 Tubulin-specific chaperone C N-terminal domain Anoctamin PF04547.12 KXS18690.1 - 5.9e-13 48.5 0.0 5.9e-13 48.5 0.0 1.0 1 0 0 1 1 1 1 Calcium-activated chloride channel Aldo_ket_red PF00248.21 KXS18691.1 - 9.4e-66 222.0 0.0 1.1e-65 221.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family MRP-L47 PF06984.13 KXS18692.1 - 6.6e-29 99.9 1.3 1.3e-28 98.9 1.3 1.5 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) FRG1 PF06229.12 KXS18693.1 - 1.3e-24 86.9 0.4 8.5e-23 81.1 0.4 2.2 1 1 0 1 1 1 1 FRG1-like domain Fascin PF06268.13 KXS18693.1 - 4.1e-06 27.0 0.0 1.2e-05 25.5 0.0 1.7 1 1 1 2 2 2 1 Fascin domain DUF1754 PF08555.10 KXS18693.1 - 0.0066 17.2 2.0 0.0066 17.2 2.0 1.8 2 0 0 2 2 2 1 Eukaryotic family of unknown function (DUF1754) VID27 PF08553.10 KXS18694.1 - 1.3e-130 435.6 0.0 1.8e-130 435.2 0.0 1.2 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain VID27_N PF17748.1 KXS18694.1 - 1e-25 90.5 7.2 1.6e-24 86.7 0.0 3.3 3 0 0 3 3 3 2 VID27 N-terminal region VID27_PH PF17747.1 KXS18694.1 - 3.2e-09 37.0 0.0 1.3e-08 35.1 0.0 2.1 2 0 0 2 2 2 1 VID27 PH-like domain Lactamase_B_2 PF12706.7 KXS18695.1 - 2.7e-27 95.6 0.0 4.7e-27 94.8 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Acetyltransf_7 PF13508.7 KXS18695.1 - 3.2e-06 27.5 0.0 7.6e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Lactamase_B PF00753.27 KXS18695.1 - 6.2e-06 26.4 0.0 1.9e-05 24.8 0.0 1.8 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Acetyltransf_1 PF00583.25 KXS18695.1 - 0.00017 21.8 0.0 0.002 18.4 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXS18695.1 - 0.015 15.3 0.0 0.47 10.4 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain AAA_23 PF13476.6 KXS18696.1 - 2.9e-16 60.6 0.6 6.7e-16 59.4 0.6 1.6 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.19 KXS18696.1 - 7e-12 45.3 0.0 1.4e-11 44.3 0.0 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 KXS18696.1 - 3.6e-05 23.7 0.1 7.8e-05 22.5 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_13 PF13166.6 KXS18696.1 - 0.0001 21.1 2.1 0.075 11.7 1.1 2.1 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.27 KXS18696.1 - 0.00032 21.2 0.7 0.02 15.4 0.0 2.4 3 0 0 3 3 2 1 ABC transporter AAA_27 PF13514.6 KXS18696.1 - 0.00039 20.1 2.5 0.052 13.1 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_21 PF13304.6 KXS18696.1 - 0.00047 20.1 2.9 0.00083 19.3 0.5 2.2 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KXS18696.1 - 0.00067 19.3 0.0 0.0013 18.5 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain PspA_IM30 PF04012.12 KXS18696.1 - 0.0054 16.3 1.0 0.01 15.4 1.0 1.3 1 0 0 1 1 1 1 PspA/IM30 family Golgin_A5 PF09787.9 KXS18696.1 - 0.013 15.0 2.6 0.02 14.4 2.6 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF4349 PF14257.6 KXS18696.1 - 0.013 14.9 1.7 0.02 14.3 1.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) Spc7 PF08317.11 KXS18696.1 - 0.015 14.2 4.7 0.024 13.6 4.7 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein EzrA PF06160.12 KXS18696.1 - 0.024 12.8 2.0 0.04 12.1 2.0 1.4 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA UvrA_DNA-bind PF17755.1 KXS18696.1 - 0.026 14.9 0.0 0.077 13.4 0.0 1.9 1 1 0 1 1 1 0 UvrA DNA-binding domain AAA_22 PF13401.6 KXS18696.1 - 0.026 14.8 0.1 0.14 12.4 0.0 2.2 1 1 1 2 2 2 0 AAA domain NACHT PF05729.12 KXS18696.1 - 0.035 14.0 0.0 0.078 12.9 0.0 1.6 1 0 0 1 1 1 0 NACHT domain Laminin_II PF06009.12 KXS18696.1 - 0.044 13.8 0.6 0.08 13.0 0.6 1.4 1 0 0 1 1 1 0 Laminin Domain II YabA PF06156.13 KXS18696.1 - 0.047 14.3 2.3 0.16 12.6 2.1 1.9 1 1 0 1 1 1 0 Initiation control protein YabA Na_trans_assoc PF06512.13 KXS18696.1 - 0.049 13.9 0.0 0.066 13.5 0.0 1.2 1 0 0 1 1 1 0 Sodium ion transport-associated FtsK_SpoIIIE PF01580.18 KXS18696.1 - 0.07 12.5 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family COG2 PF06148.11 KXS18696.1 - 0.074 13.1 1.0 0.59 10.2 0.1 2.3 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 JIP_LZII PF16471.5 KXS18696.1 - 0.089 13.0 4.7 4.1 7.6 0.3 2.4 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II tRNA_lig_CPD PF08302.11 KXS18696.1 - 0.13 11.7 0.7 3.5 7.0 0.2 2.1 1 1 1 2 2 2 0 Fungal tRNA ligase phosphodiesterase domain SNARE PF05739.19 KXS18696.1 - 0.16 12.0 0.4 3.2 7.8 0.1 2.4 2 0 0 2 2 2 0 SNARE domain FlaC_arch PF05377.11 KXS18696.1 - 0.16 12.4 1.6 14 6.2 0.1 2.8 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF641 PF04859.12 KXS18696.1 - 0.24 11.7 2.9 0.46 10.8 2.9 1.4 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Prefoldin_2 PF01920.20 KXS18696.1 - 0.26 11.3 4.9 0.82 9.7 0.4 2.3 1 1 1 2 2 2 0 Prefoldin subunit GAS PF13851.6 KXS18696.1 - 0.31 10.4 8.7 0.23 10.8 3.8 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding MMR_HSR1 PF01926.23 KXS18696.1 - 0.32 11.1 1.1 0.95 9.6 0.1 2.2 2 1 0 2 2 2 0 50S ribosome-binding GTPase TMF_TATA_bd PF12325.8 KXS18696.1 - 0.33 11.2 10.0 0.5 10.6 3.3 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DHR10 PF18595.1 KXS18696.1 - 0.4 10.7 12.0 1.9 8.6 4.9 2.3 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain DUF1151 PF06625.11 KXS18696.1 - 0.4 10.6 4.3 0.71 9.8 4.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1151) Syntaxin-6_N PF09177.11 KXS18696.1 - 0.55 10.8 7.0 2.3 8.8 6.8 2.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DivIC PF04977.15 KXS18696.1 - 0.91 9.3 4.4 0.56 10.0 0.7 2.2 2 0 0 2 2 2 0 Septum formation initiator TPR_MLP1_2 PF07926.12 KXS18696.1 - 1.2 9.2 12.4 4.8 7.3 6.0 2.2 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein SOAR PF16533.5 KXS18696.1 - 3.5 7.7 7.3 1.6 8.7 1.3 3.0 3 1 0 4 4 3 0 STIM1 Orai1-activating region CCDC-167 PF15188.6 KXS18696.1 - 4.6 7.7 7.0 6 7.3 0.5 2.7 3 0 0 3 3 2 0 Coiled-coil domain-containing protein 167 DUF1674 PF07896.12 KXS18697.1 - 6.4e-21 74.6 6.8 1.5e-20 73.3 6.8 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1674) RNA_pol_Rpb1_5 PF04998.17 KXS18698.1 - 1.4e-91 306.7 0.0 2.3e-91 306.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 KXS18698.1 - 1.7e-61 207.3 0.0 2.9e-61 206.5 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 KXS18698.1 - 1.1e-32 113.2 0.0 2.9e-32 111.8 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.12 KXS18698.1 - 3.5e-26 92.3 0.2 4.3e-20 72.3 0.0 3.9 3 1 0 3 3 3 3 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.17 KXS18698.1 - 2.4e-22 78.9 0.0 6.4e-22 77.6 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Neugrin PF06413.11 KXS18698.1 - 0.12 12.3 13.9 0.57 10.2 9.1 3.0 2 1 0 2 2 2 0 Neugrin BUD22 PF09073.10 KXS18698.1 - 0.84 8.9 35.5 0.23 10.8 28.7 2.2 2 0 0 2 2 2 0 BUD22 MFS_1 PF07690.16 KXS18700.1 - 8.5e-43 146.6 55.2 1.6e-42 145.7 53.2 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF3568 PF12092.8 KXS18700.1 - 0.077 13.1 0.5 0.17 12.0 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3568) Sec20 PF03908.13 KXS18701.1 - 1.3e-15 57.1 3.9 2.4e-15 56.2 2.4 2.1 2 0 0 2 2 2 1 Sec20 MutS_III PF05192.18 KXS18701.1 - 0.027 14.7 4.6 2.1 8.5 2.3 2.2 2 0 0 2 2 2 0 MutS domain III Nnf1 PF03980.14 KXS18701.1 - 0.032 14.6 4.6 2.6 8.5 0.3 2.4 2 0 0 2 2 2 0 Nnf1 LMBR1 PF04791.16 KXS18701.1 - 0.13 11.1 0.1 0.16 10.8 0.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein ADP_ribosyl_GH PF03747.14 KXS18703.1 - 8.9e-50 170.1 2.2 1.1e-49 169.7 2.2 1.1 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase Ufm1 PF03671.14 KXS18703.1 - 0.17 12.0 0.0 0.4 10.8 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin fold modifier 1 protein Rick_17kDa_Anti PF05433.15 KXS18703.1 - 0.19 11.6 0.9 1.5 8.8 0.1 2.4 2 0 0 2 2 2 0 Glycine zipper 2TM domain Med8 PF10232.9 KXS18704.1 - 7 6.2 10.4 9.2 5.8 10.1 1.5 1 1 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 WD40 PF00400.32 KXS18705.1 - 1.6e-06 28.7 5.5 13 6.9 0.0 7.1 8 0 0 8 8 8 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXS18705.1 - 0.00022 21.5 0.0 0.0051 17.1 0.0 2.8 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain ZapB PF06005.12 KXS18706.1 - 0.078 13.4 0.1 5.3 7.6 0.0 2.8 3 0 0 3 3 3 0 Cell division protein ZapB ACC_epsilon PF13822.6 KXS18706.1 - 0.1 13.3 1.9 0.25 12.0 1.9 1.7 1 0 0 1 1 1 0 Acyl-CoA carboxylase epsilon subunit Cwf_Cwc_15 PF04889.12 KXS18706.1 - 0.15 11.7 11.9 0.18 11.6 11.9 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein HSP90 PF00183.18 KXS18707.1 - 3.4e-232 771.9 30.4 4.5e-232 771.5 30.4 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 KXS18707.1 - 9.5e-16 58.3 0.0 2e-15 57.2 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KXS18707.1 - 2e-10 40.6 0.1 6e-10 39.1 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Amidinotransf PF02274.17 KXS18707.1 - 0.012 14.7 0.1 0.012 14.7 0.1 2.0 2 0 0 2 2 2 0 Amidinotransferase DUF2052 PF09747.9 KXS18707.1 - 0.24 11.5 19.9 0.16 12.1 13.4 2.3 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) PDCD2_C PF04194.13 KXS18707.1 - 9.1 6.3 18.6 0.18 11.9 9.3 2.6 3 0 0 3 3 3 0 Programmed cell death protein 2, C-terminal putative domain SMC_N PF02463.19 KXS18708.1 - 2.4e-12 46.8 0.0 5.3e-12 45.6 0.0 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain UPF0242 PF06785.11 KXS18708.1 - 0.015 15.4 2.6 0.015 15.4 2.6 3.6 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus SbcCD_C PF13558.6 KXS18708.1 - 0.051 13.8 0.0 0.16 12.2 0.0 1.9 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Baculo_PEP_C PF04513.12 KXS18708.1 - 7.3 6.6 16.6 2.4 8.2 4.0 3.5 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus LRR_8 PF13855.6 KXS18709.1 - 5.9e-18 64.4 37.3 1.6e-06 27.7 3.1 5.2 2 2 5 7 7 7 7 Leucine rich repeat LRR_4 PF12799.7 KXS18709.1 - 7.3e-17 61.2 20.6 4.6e-06 26.9 1.4 6.3 1 1 5 7 7 7 7 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KXS18709.1 - 2.5e-06 27.2 17.6 7.5 7.5 0.1 8.4 8 1 1 9 9 9 2 Leucine Rich Repeat LRR_6 PF13516.6 KXS18709.1 - 0.0019 18.1 12.2 1.8 8.8 0.1 6.5 7 0 0 7 7 7 2 Leucine Rich repeat Podoplanin PF05808.11 KXS18709.1 - 0.031 14.4 0.1 0.056 13.5 0.1 1.4 1 0 0 1 1 1 0 Podoplanin TrbC PF04956.13 KXS18709.1 - 4.7 7.5 7.9 0.32 11.3 2.2 1.9 2 0 0 2 2 2 0 TrbC/VIRB2 family kleA_kleC PF17383.2 KXS18710.1 - 0.028 14.7 0.4 0.052 13.9 0.4 1.4 1 0 0 1 1 1 0 Uncharacterized KorC regulated protein A NRBF2 PF08961.10 KXS18710.1 - 0.11 12.1 0.3 1.6 8.3 0.1 2.1 2 0 0 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator SlyX PF04102.12 KXS18710.1 - 0.13 12.9 0.0 0.3 11.7 0.0 1.6 1 0 0 1 1 1 0 SlyX adh_short PF00106.25 KXS18711.1 - 1.2e-18 67.3 0.0 2.4e-14 53.2 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase Epimerase PF01370.21 KXS18711.1 - 2.6e-06 27.1 0.0 3.5e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.6 KXS18711.1 - 4.5e-05 23.1 0.0 0.00034 20.3 0.0 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXS18711.1 - 5.3e-05 23.2 0.1 8.9e-05 22.5 0.1 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KXS18711.1 - 0.032 14.1 0.1 0.053 13.4 0.1 1.3 1 0 0 1 1 1 0 NAD(P)H-binding PPR_2 PF13041.6 KXS18712.1 - 0.0015 18.7 0.1 0.21 11.8 0.1 3.8 4 0 0 4 4 4 1 PPR repeat family PPR_3 PF13812.6 KXS18712.1 - 0.0017 18.4 0.0 0.039 14.0 0.0 2.6 1 1 1 2 2 2 2 Pentatricopeptide repeat domain PPR_long PF17177.4 KXS18712.1 - 0.054 12.8 0.0 2.4 7.4 0.0 2.4 1 1 1 2 2 2 0 Pentacotripeptide-repeat region of PRORP FKBP_C PF00254.28 KXS18713.1 - 2.7e-08 34.0 0.0 6.2e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_2 PF07719.17 KXS18713.1 - 9.7e-05 22.2 0.3 9.7e-05 22.2 0.3 3.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 KXS18713.1 - 0.00019 21.5 4.4 0.0002 21.4 2.5 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 KXS18713.1 - 0.0038 17.7 1.2 0.012 16.1 1.2 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.6 KXS18713.1 - 0.0089 16.7 7.7 0.0089 16.7 7.7 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 KXS18713.1 - 0.0093 15.6 4.0 0.19 11.4 0.0 3.5 4 0 0 4 4 4 1 TPR repeat TPR_1 PF00515.28 KXS18713.1 - 0.014 15.2 0.1 0.014 15.2 0.1 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat HemY_N PF07219.13 KXS18713.1 - 0.082 13.1 0.2 0.2 11.9 0.2 1.6 1 0 0 1 1 1 0 HemY protein N-terminus ANAPC3 PF12895.7 KXS18713.1 - 0.095 12.9 0.2 0.25 11.6 0.0 1.8 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF2111 PF09884.9 KXS18713.1 - 0.16 12.1 0.0 0.28 11.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2111) Pyrid_oxidase_2 PF13883.6 KXS18714.1 - 5.8e-25 88.2 0.0 8.4e-25 87.7 0.0 1.2 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase MFS_1 PF07690.16 KXS18715.1 - 2.5e-26 92.4 30.4 3.2e-26 92.1 30.4 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily BTG PF07742.12 KXS18716.1 - 6.4e-20 71.2 0.0 9.7e-20 70.6 0.0 1.2 1 0 0 1 1 1 1 BTG family QWRF PF04484.12 KXS18716.1 - 0.18 11.5 1.4 0.24 11.1 1.4 1.1 1 0 0 1 1 1 0 QWRF family Proteasome PF00227.26 KXS18717.1 - 1.6e-56 190.8 0.1 2.3e-56 190.3 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KXS18717.1 - 7.1e-11 41.6 0.3 2.7e-10 39.7 0.0 2.1 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature PCI PF01399.27 KXS18718.1 - 3.2e-09 37.2 0.0 9.6e-09 35.7 0.0 1.9 1 0 0 1 1 1 1 PCI domain Rpn9_C PF18261.1 KXS18718.1 - 0.096 12.3 0.2 0.24 11.0 0.2 1.7 1 0 0 1 1 1 0 Rpn9 C-terminal helix Glyco_hydro_18 PF00704.28 KXS18719.1 - 1.9e-29 103.4 0.0 2.1e-29 103.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 ETF PF01012.21 KXS18719.1 - 0.078 12.9 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Electron transfer flavoprotein domain Glyco_hydro_114 PF03537.13 KXS18719.1 - 0.12 11.7 0.0 0.12 11.7 0.0 1.3 1 1 0 1 1 1 0 Glycoside-hydrolase family GH114 Glyco_hydro_85 PF03644.13 KXS18719.1 - 0.14 11.5 0.0 0.15 11.4 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 85 Cellulase PF00150.18 KXS18720.1 - 3.4e-17 62.8 3.4 1.3e-16 60.9 3.4 1.7 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Osteopontin PF00865.18 KXS18721.1 - 0.0025 17.4 15.2 0.0033 17.0 15.2 1.1 1 0 0 1 1 1 1 Osteopontin NOA36 PF06524.12 KXS18721.1 - 1.1 8.5 9.0 1.6 8.0 9.0 1.2 1 0 0 1 1 1 0 NOA36 protein Cwf_Cwc_15 PF04889.12 KXS18721.1 - 1.2 8.9 10.0 1.6 8.4 10.0 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Astro_capsid_p PF12226.8 KXS18721.1 - 1.8 7.6 7.8 2.3 7.3 7.8 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein PAP2 PF01569.21 KXS18722.1 - 1.6e-14 53.8 6.0 6.8e-14 51.8 6.0 2.1 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 KXS18722.1 - 0.002 17.8 4.7 0.0067 16.1 4.7 2.0 1 0 0 1 1 1 1 PAP2 superfamily Vpu PF00558.19 KXS18723.1 - 0.027 14.2 0.1 0.045 13.5 0.1 1.2 1 0 0 1 1 1 0 Vpu protein eIF-3c_N PF05470.12 KXS18723.1 - 4.4 5.5 8.1 5.6 5.1 8.1 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus MaoC_dehydratas PF01575.19 KXS18725.1 - 2.1e-31 108.1 0.0 4.1e-31 107.1 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 KXS18725.1 - 6.6e-05 23.1 0.0 0.00034 20.7 0.0 2.0 2 1 0 2 2 2 1 N-terminal half of MaoC dehydratase Syntaxin PF00804.25 KXS18727.1 - 0.064 12.9 0.5 0.096 12.4 0.5 1.2 1 0 0 1 1 1 0 Syntaxin Lge1 PF11488.8 KXS18727.1 - 0.079 13.2 0.2 0.13 12.4 0.2 1.3 1 0 0 1 1 1 0 Transcriptional regulatory protein LGE1 YojJ PF10372.9 KXS18727.1 - 0.2 11.8 0.1 0.36 11.0 0.1 1.4 1 0 0 1 1 1 0 Bacterial membrane-spanning protein N-terminus ECH_1 PF00378.20 KXS18728.1 - 1.4e-58 198.2 0.0 1.8e-58 197.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXS18728.1 - 1e-39 137.0 0.1 3.1e-33 115.7 0.1 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 KXS18728.1 - 0.078 12.9 0.1 3.6 7.5 0.0 2.3 2 0 0 2 2 2 0 Peptidase family S49 F-box PF00646.33 KXS18729.1 - 0.00014 21.6 0.2 0.00037 20.3 0.2 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KXS18729.1 - 0.0016 18.3 0.6 0.0034 17.2 0.6 1.6 1 0 0 1 1 1 1 F-box-like Glyco_hydro_16 PF00722.21 KXS18730.1 - 4.1e-07 29.6 0.1 6.4e-07 29.0 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.15 KXS18730.1 - 2e-05 23.2 0.1 2.3e-05 23.0 0.1 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) AAA_16 PF13191.6 KXS18731.1 - 0.022 15.2 0.1 0.095 13.1 0.1 2.1 1 0 0 1 1 1 0 AAA ATPase domain Siah-Interact_N PF09032.11 KXS18731.1 - 3.8 7.9 5.2 12 6.3 0.0 3.1 3 0 0 3 3 3 0 Siah interacting protein, N terminal Peptidase_M49 PF03571.15 KXS18732.1 - 2.2e-236 785.5 0.0 2.6e-236 785.3 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M49 DUF3995 PF13160.6 KXS18734.1 - 0.094 13.1 0.8 2.4 8.5 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3995) DUF3530 PF12048.8 KXS18735.1 - 0.17 11.3 0.0 0.26 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) SLATT_3 PF18184.1 KXS18735.1 - 5.7 7.1 7.6 18 5.5 3.1 2.6 1 1 1 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 3 SdpI PF13630.6 KXS18736.1 - 0.039 14.1 1.0 0.039 14.1 1.0 3.9 3 2 0 3 3 3 0 SdpI/YhfL protein family F-box-like PF12937.7 KXS18737.1 - 3.8e-05 23.5 0.0 0.00012 21.9 0.0 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXS18737.1 - 0.056 13.3 0.0 0.17 11.8 0.0 1.8 1 0 0 1 1 1 0 F-box domain EB PF01683.18 KXS18738.1 - 0.0029 17.9 4.8 0.0034 17.6 4.7 1.2 1 1 0 1 1 1 1 EB module LEAP-2 PF07359.11 KXS18738.1 - 0.0061 16.4 3.8 0.0067 16.2 3.8 1.3 1 1 0 1 1 1 1 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) Conotoxin_I2 PF17557.2 KXS18738.1 - 0.036 14.2 3.3 0.051 13.7 3.3 1.2 1 0 0 1 1 1 0 I2-superfamily conotoxins Spt20 PF12090.8 KXS18738.1 - 1.6 8.3 8.8 1.7 8.2 8.8 1.0 1 0 0 1 1 1 0 Spt20 family Ribosomal_L29 PF00831.23 KXS18739.1 - 6.5 6.8 6.5 2.8 8.0 0.8 2.4 1 1 1 2 2 2 0 Ribosomal L29 protein Glyco_hydro_114 PF03537.13 KXS18740.1 - 4.9e-58 196.2 0.0 5.5e-58 196.0 0.0 1.0 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 K_oxygenase PF13434.6 KXS18743.1 - 1.5e-11 44.1 0.2 0.018 14.2 0.2 4.0 3 1 0 3 3 3 3 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KXS18743.1 - 0.044 13.8 4.8 0.13 12.2 0.4 3.1 3 1 0 3 3 3 0 FAD-NAD(P)-binding BTB PF00651.31 KXS18744.1 - 2.5e-06 27.7 0.0 4.3e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Prp19 PF08606.11 KXS18744.1 - 0.032 14.2 0.1 0.079 13.0 0.1 1.6 1 0 0 1 1 1 0 Prp19/Pso4-like GAGA PF09237.11 KXS18744.1 - 0.13 12.1 0.2 0.32 10.8 0.2 1.6 1 0 0 1 1 1 0 GAGA factor Pkinase_Tyr PF07714.17 KXS18746.1 - 4.6e-28 98.2 0.0 5.5e-28 98.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXS18746.1 - 1.4e-26 93.4 0.0 1.7e-26 93.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 KXS18746.1 - 0.0015 18.2 0.0 0.0019 17.9 0.0 1.1 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 KXS18746.1 - 0.0027 17.1 0.0 0.0036 16.7 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KXS18746.1 - 0.0043 15.9 0.0 0.0051 15.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KXS18746.1 - 0.12 12.3 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF3797 PF12677.7 KXS18750.1 - 0.028 14.3 0.1 0.062 13.2 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3797) BTB PF00651.31 KXS18750.1 - 0.082 13.1 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain Aldo_ket_red PF00248.21 KXS18751.1 - 2.5e-63 214.0 0.0 2.9e-63 213.8 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Pkinase PF00069.25 KXS18752.1 - 7.3e-40 137.0 0.0 3.6e-39 134.7 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS18752.1 - 4.8e-16 58.8 0.0 2.3e-14 53.3 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXS18752.1 - 0.00037 20.5 0.0 0.00075 19.5 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXS18752.1 - 0.004 16.0 0.2 0.0081 15.0 0.2 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KXS18752.1 - 0.0046 16.3 0.0 0.0084 15.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KXS18752.1 - 0.03 13.3 0.1 0.042 12.8 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Peptidase_M20 PF01546.28 KXS18754.1 - 6.8e-33 114.1 0.0 1e-32 113.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KXS18754.1 - 5.3e-08 32.7 0.0 1e-07 31.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KXS18754.1 - 4.1e-05 23.4 0.0 0.00026 20.8 0.0 2.1 2 1 0 2 2 2 1 Peptidase family M28 Steroid_dh PF02544.16 KXS18755.1 - 4.9e-23 81.8 0.8 1.2e-22 80.6 0.8 1.7 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 KXS18755.1 - 1.8e-06 27.6 0.1 3.1e-06 26.9 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.13 KXS18755.1 - 0.005 17.2 5.0 0.01 16.2 0.4 2.8 2 2 0 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 KXS18755.1 - 0.013 14.3 0.1 0.017 13.9 0.1 1.2 1 0 0 1 1 1 0 Ergosterol biosynthesis ERG4/ERG24 family Ank_2 PF12796.7 KXS18756.1 - 3.6e-37 126.8 0.8 1.8e-08 34.8 0.1 7.8 2 2 7 9 9 9 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXS18756.1 - 9e-18 64.4 1.4 0.00021 21.8 0.0 8.7 7 3 2 9 9 9 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXS18756.1 - 2.3e-17 61.3 0.2 9.4 7.2 0.0 12.9 14 0 0 14 14 14 2 Ankyrin repeat Ank_5 PF13857.6 KXS18756.1 - 4.8e-15 55.4 5.4 0.015 15.6 0.1 9.4 6 3 4 10 10 10 5 Ankyrin repeats (many copies) Ank PF00023.30 KXS18756.1 - 0.0006 20.2 11.9 16 6.2 0.0 9.3 11 2 0 11 11 11 1 Ankyrin repeat CENP-F_leu_zip PF10473.9 KXS18757.1 - 0.015 15.3 1.4 0.015 15.3 1.4 6.6 3 1 3 6 6 6 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Laminin_II PF06009.12 KXS18757.1 - 0.4 10.7 26.7 0.097 12.7 3.5 4.8 4 1 1 5 5 5 0 Laminin Domain II Baculo_PEP_C PF04513.12 KXS18757.1 - 2.2 8.3 12.7 26 4.8 2.8 5.1 5 1 0 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.12 KXS18757.1 - 3.9 8.0 13.6 7.4 7.1 0.9 5.5 6 1 1 7 7 7 0 Nucleopolyhedrovirus P10 protein EcoR124_C PF12008.8 KXS18758.1 - 0.15 11.7 1.2 5.8 6.5 0.0 2.6 2 1 0 2 2 2 0 Type I restriction and modification enzyme - subunit R C terminal TPR_19 PF14559.6 KXS18760.1 - 6.3e-05 23.4 0.1 0.026 15.0 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KXS18760.1 - 0.0037 18.0 11.2 0.18 12.7 0.0 5.1 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 KXS18760.1 - 0.0038 17.8 12.8 0.033 14.8 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 KXS18760.1 - 0.0061 16.7 0.5 0.76 10.0 0.0 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat HemY_N PF07219.13 KXS18760.1 - 0.64 10.2 0.0 0.64 10.2 0.0 2.6 3 0 0 3 3 3 0 HemY protein N-terminus CAF1A PF12253.8 KXS18764.1 - 4e-16 58.9 11.4 7.2e-16 58.1 11.0 1.7 1 1 0 1 1 1 1 Chromatin assembly factor 1 subunit A NPBW PF15180.6 KXS18765.1 - 0.15 11.9 0.4 0.38 10.6 0.4 1.7 1 0 0 1 1 1 0 Neuropeptides B and W SET PF00856.28 KXS18766.1 - 5e-10 40.0 0.0 1e-09 39.0 0.0 1.6 1 0 0 1 1 1 1 SET domain zf-MYND PF01753.18 KXS18766.1 - 3.5e-05 23.8 6.7 3.5e-05 23.8 6.7 2.6 2 1 0 2 2 2 1 MYND finger zinc_ribbon_2 PF13240.6 KXS18766.1 - 0.0045 16.7 1.9 0.0045 16.7 1.9 3.4 3 0 0 3 3 3 1 zinc-ribbon domain SWM_repeat PF13753.6 KXS18766.1 - 0.045 13.9 0.2 0.19 11.9 0.0 2.1 2 0 0 2 2 2 0 Putative flagellar system-associated repeat TPR_1 PF00515.28 KXS18766.1 - 0.2 11.6 1.3 17 5.5 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 KXS18766.1 - 0.86 9.9 8.9 0.11 12.8 3.0 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 KXS18766.1 - 1.7 8.9 6.8 1.1 9.5 0.1 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat DZR PF12773.7 KXS18766.1 - 5.7 7.0 23.1 0.064 13.3 2.8 3.0 2 1 1 3 3 3 0 Double zinc ribbon GIT_CC PF16559.5 KXS18767.1 - 0.0052 16.6 6.9 6.1 6.8 0.0 4.5 4 0 0 4 4 4 1 GIT coiled-coil Rho guanine nucleotide exchange factor Seryl_tRNA_N PF02403.22 KXS18767.1 - 0.032 14.5 0.6 0.032 14.5 0.6 3.4 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain FlaC_arch PF05377.11 KXS18767.1 - 0.4 11.1 6.6 61 4.1 3.3 4.3 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) FapA PF03961.13 KXS18767.1 - 0.9 8.1 4.7 0.26 9.9 0.3 2.0 2 0 0 2 2 2 0 Flagellar Assembly Protein A BRE1 PF08647.11 KXS18767.1 - 3.4 7.8 16.4 4.1 7.5 4.0 3.8 4 0 0 4 4 4 0 BRE1 E3 ubiquitin ligase DivIC PF04977.15 KXS18767.1 - 3.6 7.4 17.7 3.4 7.5 2.5 4.7 4 1 1 5 5 5 0 Septum formation initiator CLZ PF16526.5 KXS18767.1 - 4.9 7.6 13.3 0.3 11.5 1.0 3.6 3 1 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Golgin_A5 PF09787.9 KXS18767.1 - 6.4 6.1 17.3 0.039 13.4 1.6 3.0 3 0 0 3 3 3 0 Golgin subfamily A member 5 FUSC PF04632.12 KXS18767.1 - 9.9 4.5 7.2 1.4 7.3 2.3 2.0 1 1 0 2 2 2 0 Fusaric acid resistance protein family Lipase_GDSL_2 PF13472.6 KXS18768.1 - 1.2e-08 35.5 0.0 1.6e-08 35.1 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Glyco_hydro_18 PF00704.28 KXS18769.1 - 1.3e-07 31.7 0.4 2.9e-07 30.5 0.4 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 SH3_1 PF00018.28 KXS18770.1 - 4.4e-05 23.0 0.0 7.5e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KXS18770.1 - 5.3e-05 23.0 0.0 0.00011 22.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Ank_3 PF13606.6 KXS18770.1 - 0.025 15.1 2.4 0.089 13.4 0.0 3.3 6 0 0 6 6 6 0 Ankyrin repeat Ank_2 PF12796.7 KXS18770.1 - 0.047 14.3 0.1 0.5 11.0 0.0 2.6 2 1 0 2 2 2 0 Ankyrin repeats (3 copies) Ank PF00023.30 KXS18770.1 - 0.05 14.1 0.0 1.9 9.1 0.0 2.8 2 0 0 2 2 2 0 Ankyrin repeat ELO PF01151.18 KXS18771.1 - 8.8e-12 45.1 3.9 1.1e-11 44.8 3.9 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family NmrA PF05368.13 KXS18773.1 - 6.6e-21 74.9 0.0 8.8e-21 74.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXS18773.1 - 3.2e-10 40.2 0.0 6e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KXS18773.1 - 0.00029 20.4 0.1 0.00058 19.4 0.1 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 KXS18773.1 - 0.0047 17.3 0.1 0.012 16.0 0.1 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KXS18773.1 - 0.018 14.0 0.0 0.027 13.5 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family PSI_PsaH PF03244.14 KXS18773.1 - 0.039 13.5 0.0 0.061 12.8 0.0 1.2 1 0 0 1 1 1 0 Photosystem I reaction centre subunit VI DUF3237 PF11578.8 KXS18774.1 - 2e-23 82.9 0.3 2.4e-23 82.6 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) Peptidase_S37 PF05576.11 KXS18774.1 - 0.026 13.2 0.0 0.035 12.8 0.0 1.1 1 0 0 1 1 1 0 PS-10 peptidase S37 Fe_hyd_SSU PF02256.17 KXS18774.1 - 0.075 13.1 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 Iron hydrogenase small subunit VWA_2 PF13519.6 KXS18775.1 - 0.00016 22.3 0.0 0.00038 21.1 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain Trp_halogenase PF04820.14 KXS18775.1 - 0.16 10.8 0.0 0.25 10.2 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pkinase PF00069.25 KXS18776.1 - 4.1e-48 164.0 0.0 5e-48 163.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS18776.1 - 8.6e-33 113.7 0.0 1e-32 113.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXS18776.1 - 0.0038 16.1 0.0 0.0064 15.3 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase ABC1 PF03109.16 KXS18776.1 - 0.02 15.0 0.0 0.035 14.3 0.0 1.4 1 0 0 1 1 1 0 ABC1 family APH PF01636.23 KXS18776.1 - 0.051 13.5 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family YukC PF10140.9 KXS18776.1 - 0.24 10.2 0.0 0.33 9.7 0.0 1.1 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Dimer_Tnp_hAT PF05699.14 KXS18778.1 - 5.4e-09 35.7 0.0 1.7e-08 34.1 0.0 1.9 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region zf-tcix PF14952.6 KXS18779.1 - 0.7 9.6 4.4 1.1 8.9 4.4 1.3 1 0 0 1 1 1 0 Putative treble-clef, zinc-finger, Zn-binding YCII PF03795.14 KXS18781.1 - 1.9e-09 37.8 0.0 2.1e-09 37.7 0.0 1.0 1 0 0 1 1 1 1 YCII-related domain ORC4_C PF14629.6 KXS18783.1 - 7e-35 120.4 0.0 1.1e-34 119.8 0.0 1.3 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.6 KXS18783.1 - 4.5e-18 66.2 0.4 1.1e-17 65.0 0.4 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KXS18783.1 - 3.1e-09 37.2 0.0 5.8e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KXS18783.1 - 3.4e-08 34.0 0.0 1.8e-07 31.7 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 KXS18783.1 - 2.5e-05 23.6 0.0 4.4e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) NACHT PF05729.12 KXS18783.1 - 0.0013 18.7 0.1 0.45 10.4 0.0 2.3 2 0 0 2 2 2 2 NACHT domain AAA_19 PF13245.6 KXS18783.1 - 0.01 16.1 0.0 0.028 14.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KXS18783.1 - 0.025 14.1 0.0 0.047 13.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region DAP3 PF10236.9 KXS18783.1 - 0.049 12.8 0.0 1.2 8.2 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 DUF2791 PF10923.8 KXS18783.1 - 0.054 12.3 0.0 0.13 11.1 0.0 1.6 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) AAA_5 PF07728.14 KXS18783.1 - 0.078 13.0 0.1 0.58 10.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) YjeF_N PF03853.15 KXS18784.1 - 2.7e-10 40.4 0.6 5.2e-10 39.5 0.6 1.4 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.10 KXS18784.1 - 0.04 14.8 3.2 0.7 10.8 0.0 2.4 2 0 0 2 2 2 0 FDF domain DUF150_C PF17384.2 KXS18784.1 - 0.17 12.0 0.7 0.33 11.1 0.1 1.8 2 0 0 2 2 2 0 RimP C-terminal SH3 domain LSM PF01423.22 KXS18784.1 - 0.26 11.0 0.2 0.43 10.3 0.2 1.3 1 0 0 1 1 1 0 LSM domain Macoilin PF09726.9 KXS18784.1 - 3.3 6.1 4.1 4.9 5.6 4.1 1.1 1 0 0 1 1 1 0 Macoilin family SelP_N PF04592.14 KXS18784.1 - 3.9 6.8 14.2 6.6 6.1 14.2 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Methyltransf_21 PF05050.12 KXS18786.1 - 1.9e-08 34.5 0.0 2.3e-06 27.8 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase FkbM domain Mito_fiss_reg PF05308.11 KXS18787.1 - 1 9.4 3.8 1.1 9.3 3.8 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 KXS18787.1 - 2.9 7.3 5.8 3.5 7.0 5.8 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal GST_C PF00043.25 KXS18788.1 - 1.8e-11 44.1 0.1 3.3e-11 43.2 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KXS18788.1 - 6.2e-08 32.7 0.0 1e-07 32.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KXS18788.1 - 3.3e-06 27.3 0.0 7.1e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KXS18788.1 - 1.5e-05 24.9 0.0 3.3e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KXS18788.1 - 9.9e-05 22.7 0.0 0.0002 21.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KXS18788.1 - 0.00012 22.3 0.0 0.0002 21.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Soc PF16855.5 KXS18788.1 - 0.018 15.5 0.0 7.5 7.1 0.0 2.3 2 0 0 2 2 2 0 Small outer capsid protein NPP1 PF05630.11 KXS18789.1 - 2e-14 54.2 0.0 4e-14 53.2 0.0 1.5 1 1 0 1 1 1 1 Necrosis inducing protein (NPP1) GST_C PF00043.25 KXS18790.1 - 9.7e-09 35.3 0.0 1.3e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KXS18790.1 - 1.6e-06 28.2 0.0 2.7e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KXS18790.1 - 9.9e-06 25.8 0.0 1.7e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KXS18790.1 - 2.1e-05 24.4 0.0 3.8e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KXS18790.1 - 0.00028 21.1 0.0 0.00047 20.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KXS18790.1 - 0.00029 21.2 0.0 0.00056 20.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain zf-C2H2 PF00096.26 KXS18791.1 - 1.7e-06 28.2 8.7 0.00065 20.0 1.8 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXS18791.1 - 0.011 16.5 1.2 0.011 16.5 1.2 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KXS18791.1 - 0.026 14.3 1.7 0.06 13.1 1.7 1.6 1 0 0 1 1 1 0 zinc-finger C2H2-type zf-C2H2 PF00096.26 KXS18792.1 - 1.7e-10 40.8 10.5 3.1e-05 24.2 0.5 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXS18792.1 - 0.00071 20.2 4.9 0.013 16.2 0.6 3.4 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KXS18792.1 - 0.0042 17.3 1.6 0.82 10.0 0.0 2.7 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 KXS18792.1 - 0.017 15.4 1.7 0.017 15.4 1.7 2.4 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding Serglycin PF04360.12 KXS18792.1 - 0.079 12.9 1.8 0.3 11.0 1.8 2.0 1 0 0 1 1 1 0 Serglycin zf-C2H2_aberr PF17017.5 KXS18792.1 - 0.1 12.7 0.2 0.15 12.2 0.2 1.2 1 0 0 1 1 1 0 Aberrant zinc-finger FOXP-CC PF16159.5 KXS18792.1 - 0.2 12.3 7.2 8.3 7.1 0.2 3.4 2 1 1 3 3 3 0 FOXP coiled-coil domain zf-H2C2_2 PF13465.6 KXS18792.1 - 0.24 11.9 10.1 1.4 9.5 0.8 3.5 3 0 0 3 3 3 0 Zinc-finger double domain Lyase_1 PF00206.20 KXS18793.1 - 6.4e-19 68.5 0.0 1e-18 67.8 0.0 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 KXS18793.1 - 3.3e-18 66.0 0.0 7.9e-18 64.8 0.0 1.7 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus DUF1331 PF07048.11 KXS18793.1 - 0.13 12.0 0.1 0.33 10.6 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1331) APG6_N PF17675.1 KXS18794.1 - 0.048 14.2 4.5 0.074 13.6 4.5 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region FliJ PF02050.16 KXS18794.1 - 0.24 11.6 2.6 0.39 11.0 2.6 1.3 1 0 0 1 1 1 0 Flagellar FliJ protein Spc7 PF08317.11 KXS18794.1 - 0.49 9.2 3.5 0.68 8.8 3.5 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein ADIP PF11559.8 KXS18794.1 - 0.96 9.5 5.9 2.1 8.4 5.9 1.5 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding GIT1_C PF12205.8 KXS18794.1 - 1.3 9.2 6.0 0.67 10.1 1.3 2.1 1 1 1 2 2 2 0 G protein-coupled receptor kinase-interacting protein 1 C term FR47 PF08445.10 KXS18795.1 - 2.4e-09 37.0 0.0 3.8e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_1 PF00583.25 KXS18795.1 - 1.3e-08 35.1 0.0 1.7e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXS18795.1 - 2.3e-07 30.8 0.0 3.1e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KXS18795.1 - 7.4e-06 26.1 0.0 1e-05 25.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KXS18795.1 - 2.8e-05 23.8 0.0 0.00017 21.3 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXS18795.1 - 9.6e-05 22.7 0.0 0.00014 22.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Robl_LC7 PF03259.17 KXS18795.1 - 0.062 13.1 0.0 0.2 11.4 0.0 1.8 2 0 0 2 2 2 0 Roadblock/LC7 domain GTP_EFTU PF00009.27 KXS18796.1 - 0.00084 18.9 0.0 0.0015 18.1 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KXS18796.1 - 0.072 13.2 0.0 0.41 10.7 0.0 2.0 2 0 0 2 2 2 0 50S ribosome-binding GTPase cobW PF02492.19 KXS18796.1 - 0.15 11.6 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Spt5_N PF11942.8 KXS18796.1 - 2.6 9.1 10.9 0.56 11.2 7.3 1.7 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal FAM183 PF14886.6 KXS18798.1 - 8.3e-18 65.1 0.0 1e-17 64.8 0.0 1.1 1 0 0 1 1 1 1 FAM183A and FAM183B related Aldedh PF00171.22 KXS18801.1 - 1.1e-160 535.2 0.2 1.2e-160 535.0 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KXS18801.1 - 0.00019 20.9 0.0 0.051 13.0 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) PYNP_C PF07831.13 KXS18801.1 - 0.13 11.9 0.1 0.34 10.6 0.1 1.6 1 0 0 1 1 1 0 Pyrimidine nucleoside phosphorylase C-terminal domain Thioredoxin PF00085.20 KXS18803.1 - 2e-28 98.4 0.0 2.3e-28 98.2 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 KXS18803.1 - 5.1e-06 26.7 0.1 2.3e-05 24.6 0.1 2.1 1 1 1 2 2 2 1 Thioredoxin-like AhpC-TSA PF00578.21 KXS18803.1 - 5.1e-05 23.2 0.1 7.1e-05 22.7 0.1 1.3 1 1 0 1 1 1 1 AhpC/TSA family OST3_OST6 PF04756.13 KXS18803.1 - 0.00012 21.6 0.0 0.00013 21.4 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 KXS18803.1 - 0.00022 21.6 0.1 0.0006 20.2 0.1 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.10 KXS18803.1 - 0.001 18.8 0.0 0.0012 18.5 0.0 1.2 1 0 0 1 1 1 1 Redoxin Thioredoxin_7 PF13899.6 KXS18803.1 - 0.0013 18.9 0.1 0.0018 18.4 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.6 KXS18803.1 - 0.0035 17.1 0.0 0.004 16.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Glutaredoxin PF00462.24 KXS18803.1 - 0.011 16.0 0.1 0.019 15.2 0.1 1.5 1 1 0 1 1 1 0 Glutaredoxin Phosducin PF02114.16 KXS18803.1 - 0.057 12.4 0.0 0.07 12.1 0.0 1.1 1 0 0 1 1 1 0 Phosducin ERCC3_RAD25_C PF16203.5 KXS18804.1 - 1.4e-119 397.8 0.3 2.5e-119 397.0 0.3 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 KXS18804.1 - 2.9e-36 124.4 0.0 6.7e-36 123.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXS18804.1 - 4.7e-18 65.8 0.0 9.6e-18 64.8 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KXS18804.1 - 2.1e-12 47.4 0.2 5.3e-12 46.1 0.2 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 KXS18804.1 - 4.5e-08 32.2 0.0 5.7e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.29 KXS18804.1 - 0.00014 21.7 0.0 0.00033 20.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase F-box-like PF12937.7 KXS18806.1 - 7e-09 35.4 3.1 7e-09 35.4 3.1 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KXS18806.1 - 5.7e-06 26.1 1.8 1.2e-05 25.1 1.0 2.0 2 0 0 2 2 2 1 F-box domain LRR_4 PF12799.7 KXS18806.1 - 0.00034 20.9 7.0 0.26 11.8 0.2 3.8 3 1 0 4 4 4 2 Leucine Rich repeats (2 copies) Mak16 PF04874.14 KXS18806.1 - 0.052 14.2 0.8 0.09 13.4 0.8 1.3 1 0 0 1 1 1 0 Mak16 protein C-terminal region LRR_8 PF13855.6 KXS18806.1 - 0.13 12.1 0.4 0.54 10.1 0.1 2.3 2 1 0 2 2 2 0 Leucine rich repeat LRR_1 PF00560.33 KXS18806.1 - 0.23 12.1 1.8 12 6.9 0.1 4.3 4 1 0 4 4 4 0 Leucine Rich Repeat SDA1 PF05285.12 KXS18806.1 - 4.5 6.6 4.8 6.5 6.1 4.8 1.1 1 0 0 1 1 1 0 SDA1 DNA_pol_phi PF04931.13 KXS18806.1 - 4.8 5.2 8.2 7.7 4.5 8.2 1.2 1 0 0 1 1 1 0 DNA polymerase phi DAGK_cat PF00781.24 KXS18807.1 - 3.6e-23 81.5 0.0 7.2e-23 80.6 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain IF-2B PF01008.17 KXS18808.1 - 1.6e-67 227.7 0.0 1.9e-67 227.5 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family HAP2-GCS1 PF10699.9 KXS18808.1 - 0.021 14.8 0.0 0.056 13.4 0.0 1.7 1 0 0 1 1 1 0 Male gamete fusion factor Thiolase_N PF00108.23 KXS18809.1 - 2.7e-70 236.7 0.7 4.4e-70 236.0 0.7 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KXS18809.1 - 2.4e-47 159.6 1.1 5.4e-47 158.5 1.1 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KXS18809.1 - 0.00014 21.6 1.3 0.0017 17.9 0.4 2.7 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KXS18809.1 - 0.0048 16.7 0.4 0.89 9.4 0.1 2.4 2 0 0 2 2 2 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ACP_syn_III_C PF08541.10 KXS18809.1 - 0.09 13.0 0.0 0.27 11.4 0.0 1.8 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal zf-C2H2 PF00096.26 KXS18810.1 - 7.5e-09 35.6 14.9 4.4e-05 23.7 2.2 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KXS18810.1 - 8.7e-06 25.9 0.3 2.8e-05 24.3 0.2 2.0 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 KXS18810.1 - 0.00011 22.5 11.6 0.00012 22.3 2.9 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KXS18810.1 - 0.00013 22.5 14.7 0.0011 19.6 1.7 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.7 KXS18810.1 - 0.0004 20.7 0.4 0.0004 20.7 0.4 2.2 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KXS18810.1 - 0.00047 20.1 1.1 0.00047 20.1 1.1 1.9 2 0 0 2 2 2 1 C2H2-type zinc finger FOXP-CC PF16159.5 KXS18810.1 - 0.038 14.6 5.3 0.93 10.2 0.1 3.0 1 1 2 3 3 3 0 FOXP coiled-coil domain zf-Di19 PF05605.12 KXS18810.1 - 0.15 12.4 4.7 1.7 9.0 0.5 2.3 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding ASH PF15780.5 KXS18811.1 - 3.8e-51 171.3 15.5 0.00016 21.8 0.0 19.5 20 2 0 21 21 21 10 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 KXS18811.1 - 8.2e-21 73.9 0.3 5.3e-05 23.0 0.0 11.9 12 0 0 12 12 12 3 MSP (Major sperm protein) domain DUF1573 PF07610.11 KXS18811.1 - 5.8e-13 48.7 1.5 1.1 9.3 0.0 10.6 10 1 0 10 10 10 3 Protein of unknown function (DUF1573) TMEM131_like PF12371.8 KXS18811.1 - 5.8e-08 32.9 3.1 6.4 7.1 0.0 10.7 14 0 0 14 14 14 2 Transmembrane protein 131-like PapD-like PF14874.6 KXS18811.1 - 2.2e-05 24.5 1.5 22 5.3 0.0 7.6 8 0 0 8 8 8 1 Flagellar-associated PapD-like NTP_transf_2 PF01909.23 KXS18812.1 - 4.9e-05 23.5 0.0 0.00011 22.5 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Elf1 PF05129.13 KXS18813.1 - 4.5e-26 90.7 1.0 5.4e-26 90.4 1.0 1.1 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like zf-Mss51 PF13824.6 KXS18813.1 - 0.0023 18.0 0.4 0.0032 17.5 0.4 1.2 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 Lar_restr_allev PF14354.6 KXS18813.1 - 0.0027 18.1 0.2 0.0047 17.3 0.2 1.4 1 0 0 1 1 1 1 Restriction alleviation protein Lar Vps36-NZF-N PF16988.5 KXS18813.1 - 0.012 15.0 0.4 0.017 14.5 0.4 1.4 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Cys_rich_CPXG PF14255.6 KXS18813.1 - 0.018 14.9 0.2 0.025 14.5 0.2 1.3 1 0 0 1 1 1 0 Cysteine-rich CPXCG Zn_Tnp_IS1595 PF12760.7 KXS18813.1 - 0.026 14.5 1.0 0.085 12.8 1.1 1.8 1 1 1 2 2 2 0 Transposase zinc-ribbon domain T4_baseplate PF12322.8 KXS18813.1 - 0.1 12.1 0.2 0.15 11.5 0.2 1.2 1 0 0 1 1 1 0 T4 bacteriophage base plate protein DUF4931 PF16285.5 KXS18813.1 - 0.2 10.9 0.1 0.2 10.9 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4931) CEP44 PF15007.6 KXS18815.1 - 1.1e-34 119.3 0.0 1.8e-34 118.6 0.0 1.3 1 0 0 1 1 1 1 Centrosomal spindle body, CEP44 DUF1122 PF06557.11 KXS18815.1 - 0.19 11.1 0.0 0.33 10.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1122) HEAT PF02985.22 KXS18817.1 - 2.6e-06 27.2 2.5 0.02 15.1 0.0 3.5 4 0 0 4 4 4 2 HEAT repeat HEAT_EZ PF13513.6 KXS18817.1 - 0.0018 18.7 0.9 0.0081 16.6 0.0 2.5 4 0 0 4 4 4 1 HEAT-like repeat Cnd1 PF12717.7 KXS18817.1 - 0.0021 18.1 0.1 0.0026 17.8 0.1 1.2 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KXS18817.1 - 0.0022 18.3 0.0 0.0052 17.2 0.0 1.6 1 1 0 1 1 1 1 HEAT repeats Aldedh PF00171.22 KXS18817.1 - 0.042 12.4 0.0 0.054 12.0 0.0 1.1 1 0 0 1 1 1 0 Aldehyde dehydrogenase family Vac14_Fab1_bd PF12755.7 KXS18817.1 - 0.1 13.2 0.0 0.17 12.5 0.0 1.3 1 0 0 1 1 1 0 Vacuolar 14 Fab1-binding region Transketolase_N PF00456.21 KXS18818.1 - 4.9e-151 502.4 0.0 6.3e-151 502.0 0.0 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 KXS18818.1 - 5.2e-46 156.5 0.0 1.6e-45 155.0 0.0 1.8 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KXS18818.1 - 5.5e-11 42.4 0.1 4.3e-10 39.5 0.1 2.2 1 1 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 KXS18818.1 - 2.4e-07 30.2 0.1 3.8e-07 29.6 0.1 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 KXS18818.1 - 0.00012 21.8 0.6 0.001 18.9 0.2 2.8 3 1 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain APH PF01636.23 KXS18819.1 - 5.9e-36 124.6 0.0 8.5e-36 124.1 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KXS18819.1 - 3.8e-05 23.4 0.0 5.2e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.20 KXS18819.1 - 0.00042 19.7 0.0 0.00067 19.1 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase Phage_lambda_P PF06992.11 KXS18819.1 - 0.12 12.0 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Replication protein P Pkinase PF00069.25 KXS18820.1 - 2e-68 230.6 0.0 2.4e-68 230.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS18820.1 - 2.3e-34 118.8 0.0 3e-34 118.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 KXS18820.1 - 3.1e-07 31.0 0.2 8.8e-07 29.5 0.2 1.9 1 1 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 KXS18820.1 - 4.7e-07 29.4 0.0 8.1e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KXS18820.1 - 0.0036 17.3 2.8 0.081 12.8 0.1 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 KXS18820.1 - 0.01 15.4 0.0 0.66 9.6 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 KXS18820.1 - 0.021 14.2 0.0 0.042 13.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KXS18820.1 - 0.031 13.2 0.0 0.041 12.8 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain DUF3725 PF12523.8 KXS18820.1 - 0.11 12.8 0.0 0.23 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3725) SnoaL_2 PF12680.7 KXS18821.1 - 0.00033 21.2 0.3 0.037 14.7 0.0 2.1 2 0 0 2 2 2 2 SnoaL-like domain DUF4440 PF14534.6 KXS18821.1 - 0.00038 20.8 0.0 0.00062 20.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) Lumazine_bd_2 PF12893.7 KXS18821.1 - 0.087 13.5 0.0 0.14 12.8 0.0 1.3 1 0 0 1 1 1 0 Putative lumazine-binding APH PF01636.23 KXS18822.1 - 5.5e-15 56.0 0.1 8.2e-15 55.4 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 KXS18822.1 - 0.0041 16.5 0.2 0.0063 15.9 0.2 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.20 KXS18822.1 - 0.0046 16.6 0.1 0.0067 16.0 0.1 1.1 1 0 0 1 1 1 1 Choline/ethanolamine kinase zf-C2H2 PF00096.26 KXS18824.1 - 2.2e-11 43.5 16.0 0.00019 21.7 1.0 3.2 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KXS18824.1 - 3.6e-09 36.6 18.2 4.5e-06 26.8 1.3 4.5 4 1 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KXS18824.1 - 4.7e-09 36.3 16.8 0.002 18.8 0.5 3.2 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KXS18824.1 - 0.00026 21.2 4.9 0.017 15.4 0.2 3.2 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 KXS18824.1 - 0.031 14.0 1.9 0.031 14.0 1.9 3.5 3 2 0 3 3 3 0 zinc-finger C2H2-type zf-met PF12874.7 KXS18824.1 - 0.032 14.6 8.8 0.16 12.4 0.4 3.4 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf_ZIC PF18366.1 KXS18824.1 - 0.037 14.2 3.2 0.53 10.4 0.4 2.9 2 1 1 3 3 3 0 Zic proteins zinc finger domain zf-C2H2_6 PF13912.6 KXS18824.1 - 2.9 8.0 13.6 0.91 9.6 0.6 3.2 3 1 0 3 3 3 0 C2H2-type zinc finger zf-AN1 PF01428.16 KXS18824.1 - 4.7 7.5 14.5 25 5.1 6.4 3.4 1 1 1 2 2 2 0 AN1-like Zinc finger Cyt-b5 PF00173.28 KXS18825.1 - 2e-18 66.3 0.0 3e-18 65.7 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Inhibitor_I53 PF11714.8 KXS18825.1 - 0.59 10.4 2.1 1.5 9.1 2.1 1.6 1 0 0 1 1 1 0 Thrombin inhibitor Madanin HIT PF01230.23 KXS18826.1 - 6.4e-23 81.3 0.0 1.3e-22 80.4 0.0 1.4 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KXS18826.1 - 9.6e-06 26.1 0.0 1.6e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding ASH PF15780.5 KXS18827.1 - 4.1e-09 36.5 6.3 4.7 7.5 0.0 9.3 10 1 0 10 10 10 4 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin DUF1573 PF07610.11 KXS18827.1 - 0.0001 22.3 0.8 24 5.1 0.0 7.4 8 1 0 8 8 8 1 Protein of unknown function (DUF1573) Transglut_C PF00927.22 KXS18827.1 - 0.0024 18.0 0.2 0.16 12.1 0.0 3.6 3 0 0 3 3 3 1 Transglutaminase family, C-terminal ig like domain PapD-like PF14874.6 KXS18827.1 - 0.015 15.4 0.3 68 3.7 0.0 5.3 6 0 0 6 6 6 0 Flagellar-associated PapD-like Pex24p PF06398.11 KXS18828.1 - 0.016 14.3 0.7 0.019 14.0 0.7 1.1 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin Nucleoporin_FG2 PF15967.5 KXS18829.1 - 4.3e-09 35.5 0.0 4.3e-09 35.5 0.0 3.1 3 0 0 3 3 3 2 Nucleoporin FG repeated region Nucleoporin_FG PF13634.6 KXS18829.1 - 0.023 15.5 5.0 0.023 15.5 5.0 2.4 2 1 0 2 2 2 0 Nucleoporin FG repeat region Syntaxin-6_N PF09177.11 KXS18829.1 - 0.085 13.4 3.8 9.2 6.9 0.5 3.2 1 1 2 3 3 3 0 Syntaxin 6, N-terminal DUF2274 PF10038.9 KXS18829.1 - 0.48 10.9 2.5 0.89 10.1 0.0 2.7 4 1 0 4 4 4 0 Protein of unknown function (DUF2274) DUF2205 PF10224.9 KXS18829.1 - 0.8 9.7 2.8 5.9 7.0 0.3 2.3 2 0 0 2 2 2 0 Short coiled-coil protein WD40 PF00400.32 KXS18830.1 - 1.2e-63 209.5 25.4 2.3e-10 40.9 0.8 7.7 7 1 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXS18830.1 - 8.4e-20 70.9 0.1 1.4e-05 25.3 0.0 6.0 2 2 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KXS18830.1 - 4.3e-14 52.1 13.8 0.00027 19.7 0.1 6.4 3 3 4 7 7 7 5 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 KXS18830.1 - 2.2e-06 26.7 0.1 0.22 10.2 0.0 4.5 1 1 3 5 5 5 2 Nup133 N terminal like Ge1_WD40 PF16529.5 KXS18830.1 - 2.9e-05 23.2 9.3 0.35 9.8 0.2 5.5 1 1 5 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KXS18830.1 - 0.00051 20.0 0.3 0.031 14.1 0.1 2.6 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A LisH PF08513.11 KXS18830.1 - 0.0025 17.7 0.1 0.005 16.8 0.1 1.5 1 0 0 1 1 1 1 LisH Cytochrom_D1 PF02239.16 KXS18830.1 - 0.011 14.3 0.3 3.5 6.1 0.0 2.6 3 0 0 3 3 3 0 Cytochrome D1 heme domain Frtz PF11768.8 KXS18830.1 - 0.085 11.2 0.0 1.4 7.2 0.0 2.5 2 1 1 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz nos_propeller PF18764.1 KXS18830.1 - 0.094 12.6 0.0 11 6.0 0.0 3.3 3 0 0 3 3 3 0 Nitrous oxide reductase propeller repeat PALB2_WD40 PF16756.5 KXS18830.1 - 0.12 11.2 5.0 3.5 6.5 0.1 4.2 3 2 2 5 5 5 0 Partner and localizer of BRCA2 WD40 domain NHL PF01436.21 KXS18830.1 - 0.13 12.4 0.1 4.7 7.4 0.1 3.3 4 0 0 4 4 4 0 NHL repeat Neurensin PF14927.6 KXS18833.1 - 0.009 15.7 0.0 0.0094 15.7 0.0 1.1 1 0 0 1 1 1 1 Neurensin Kinesin PF00225.23 KXS18834.1 - 1.5e-93 313.4 0.0 1.8e-93 313.1 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KXS18834.1 - 1.7e-14 54.0 0.0 3.2e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding MCM_N PF14551.6 KXS18835.1 - 0.038 14.6 1.6 0.12 13.0 0.3 2.2 2 0 0 2 2 2 0 MCM N-terminal domain Jnk-SapK_ap_N PF09744.9 KXS18835.1 - 0.29 11.3 20.0 4.4 7.5 11.2 3.0 2 1 0 2 2 2 0 JNK_SAPK-associated protein-1 DUF4407 PF14362.6 KXS18835.1 - 3.2 7.0 8.6 3.2 7.0 7.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4337 PF14235.6 KXS18835.1 - 7.2 6.7 9.5 0.63 10.1 4.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) UPF0449 PF15136.6 KXS18835.1 - 7.5 7.1 12.9 2.6 8.5 0.2 3.2 2 1 1 3 3 3 0 Uncharacterised protein family UPF0449 WD40 PF00400.32 KXS18836.1 - 1.1e-42 143.1 18.8 2.5e-06 28.1 0.1 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.7 KXS18836.1 - 1.2e-10 41.1 0.2 3.2e-10 39.7 0.2 1.8 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 KXS18836.1 - 2.6e-09 37.2 1.3 0.19 12.0 0.0 5.2 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KXS18836.1 - 1.6e-07 30.3 1.8 0.71 8.4 0.1 5.0 2 1 3 5 5 5 4 Nucleoporin Nup120/160 WD40_like PF17005.5 KXS18836.1 - 1.8e-05 24.2 0.1 0.0074 15.7 0.3 2.9 1 1 1 2 2 2 2 WD40-like domain PQQ_2 PF13360.6 KXS18836.1 - 4.4e-05 23.2 0.7 0.14 11.7 0.1 2.6 1 1 1 2 2 2 2 PQQ-like domain F-box PF00646.33 KXS18836.1 - 5.4e-05 23.0 0.6 0.00018 21.3 0.6 1.9 1 0 0 1 1 1 1 F-box domain DUF5046 PF16465.5 KXS18836.1 - 0.00014 21.4 0.0 0.036 13.5 0.0 2.6 1 1 1 2 2 2 2 Domain of unknown function (DUF5046) Nucleoporin_N PF08801.11 KXS18836.1 - 0.37 9.5 7.6 0.32 9.7 0.0 3.7 3 1 0 4 4 4 0 Nup133 N terminal like MitMem_reg PF13012.6 KXS18839.1 - 2.5e-31 108.4 0.2 4.8e-31 107.5 0.2 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 KXS18839.1 - 3.1e-22 78.8 0.0 4.7e-22 78.2 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Kin17_mid PF10357.9 KXS18840.1 - 9e-52 174.3 0.4 1.1e-51 174.0 0.4 1.1 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein zf-met PF12874.7 KXS18840.1 - 0.0026 18.1 6.5 0.0049 17.2 6.5 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KXS18840.1 - 0.0036 17.6 3.7 0.022 15.1 0.9 2.2 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 KXS18840.1 - 0.0056 16.9 5.7 0.0095 16.2 5.7 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding AKAP95 PF04988.12 KXS18840.1 - 0.083 13.1 1.6 0.14 12.4 1.6 1.4 1 0 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) Methyltransf_11 PF08241.12 KXS18841.1 - 7.4e-17 61.8 0.0 1.2e-16 61.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXS18841.1 - 1e-12 48.6 0.0 2.2e-12 47.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXS18841.1 - 4.2e-09 36.4 0.0 5.4e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 KXS18841.1 - 8.2e-07 29.1 0.0 1.1e-06 28.7 0.0 1.1 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_31 PF13847.6 KXS18841.1 - 8.2e-07 28.9 0.1 2.2e-06 27.6 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXS18841.1 - 1e-06 29.4 0.1 2.4e-06 28.2 0.1 1.7 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXS18841.1 - 3.7e-05 23.2 0.0 6.5e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_29 PF03141.16 KXS18841.1 - 0.0016 17.0 0.0 0.0023 16.6 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase MetW PF07021.12 KXS18841.1 - 0.022 14.4 0.0 0.033 13.8 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW NodS PF05401.11 KXS18841.1 - 0.078 12.6 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_9 PF08003.11 KXS18841.1 - 0.083 11.8 0.3 1 8.2 0.3 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1698) Ras PF00071.22 KXS18842.1 - 2.1e-56 190.0 0.3 2.4e-56 189.8 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXS18842.1 - 6e-21 74.9 0.0 8.4e-21 74.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXS18842.1 - 8e-09 35.2 0.2 8.4e-09 35.1 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KXS18842.1 - 3.9e-05 23.3 0.4 9.4e-05 22.0 0.1 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KXS18842.1 - 0.00083 19.4 0.0 0.0013 18.8 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KXS18842.1 - 0.00084 19.3 1.3 0.68 9.8 0.0 2.2 1 1 0 2 2 2 2 RsgA GTPase G-alpha PF00503.20 KXS18842.1 - 0.034 13.3 0.1 4.3 6.4 0.0 2.2 1 1 0 2 2 2 0 G-protein alpha subunit AAA_16 PF13191.6 KXS18843.1 - 3.7e-31 108.8 0.0 8.5e-31 107.6 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain Guanylate_cyc PF00211.20 KXS18843.1 - 1.4e-27 96.5 0.0 2.5e-27 95.7 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Pkinase PF00069.25 KXS18843.1 - 3.4e-20 72.5 0.0 9.7e-20 71.0 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS18843.1 - 1.9e-12 47.1 0.0 8.3e-12 44.9 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KXS18843.1 - 0.00041 20.3 0.1 0.00093 19.2 0.1 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KXS18843.1 - 0.002 17.5 0.0 0.048 13.0 0.0 2.4 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KXS18843.1 - 0.0063 15.9 0.0 0.015 14.6 0.0 1.5 1 0 0 1 1 1 1 Kinase-like NB-ARC PF00931.22 KXS18843.1 - 0.016 14.4 0.1 2.4 7.3 0.0 2.7 3 0 0 3 3 3 0 NB-ARC domain ATPase_2 PF01637.18 KXS18843.1 - 0.051 13.5 0.0 0.16 11.8 0.0 1.9 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea HK PF02110.15 KXS18845.1 - 4.1e-49 167.2 2.1 1.2e-28 100.2 0.3 2.3 1 1 1 2 2 2 2 Hydroxyethylthiazole kinase family TMP-TENI PF02581.17 KXS18845.1 - 1e-29 103.2 0.0 1.7e-29 102.5 0.0 1.3 1 0 0 1 1 1 1 Thiamine monophosphate synthase zf-TRAF PF02176.18 KXS18845.1 - 1.5e-05 25.5 0.3 4.6e-05 24.0 0.3 1.7 1 0 0 1 1 1 1 TRAF-type zinc finger HSBP1 PF06825.12 KXS18845.1 - 0.043 13.7 0.5 0.34 10.8 0.0 2.6 3 0 0 3 3 3 0 Heat shock factor binding protein 1 zf-TRAF_2 PF15965.5 KXS18845.1 - 0.062 13.8 6.1 0.14 12.7 1.5 3.1 2 1 2 4 4 4 0 TRAF-like zinc-finger Fer4_24 PF18109.1 KXS18845.1 - 0.099 12.9 3.6 10 6.5 0.0 3.5 3 0 0 3 3 3 0 Ferredoxin I 4Fe-4S cluster domain UDPG_MGDP_dh_N PF03721.14 KXS18845.1 - 0.13 11.9 1.1 0.43 10.1 0.4 2.0 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain CK2S PF15011.6 KXS18845.1 - 0.4 10.5 3.5 1.3 8.9 2.4 2.4 2 1 0 2 2 2 0 Casein Kinase 2 substrate Sugar_tr PF00083.24 KXS18846.1 - 3.6e-77 260.1 15.0 6.5e-75 252.7 15.0 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXS18846.1 - 6.4e-23 81.2 26.4 1.3e-19 70.3 8.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily HK PF02110.15 KXS18847.1 - 2.4e-74 249.8 1.1 3e-74 249.5 1.1 1.1 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.17 KXS18847.1 - 2.3e-31 108.5 0.0 4.3e-31 107.6 0.0 1.4 1 0 0 1 1 1 1 Thiamine monophosphate synthase RRM_1 PF00076.22 KXS18848.1 - 3.3e-11 42.8 0.0 4.4e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KXS18848.1 - 0.14 12.1 0.0 0.2 11.7 0.0 1.2 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif FF PF01846.19 KXS18849.1 - 1.4e-40 137.3 20.7 9.4e-15 54.5 0.7 7.0 7 0 0 7 7 7 5 FF domain WW PF00397.26 KXS18849.1 - 0.0046 17.0 0.1 0.01 15.9 0.1 1.6 1 0 0 1 1 1 1 WW domain RhoGAP-FF1 PF16512.5 KXS18849.1 - 0.0086 16.7 10.9 0.44 11.3 0.1 4.4 3 1 1 4 4 4 2 p190-A and -B Rho GAPs FF domain Cse1 PF08506.10 KXS18851.1 - 4.3e-136 453.6 0.4 9.5e-98 327.4 0.0 2.3 2 0 0 2 2 2 2 Cse1 CAS_CSE1 PF03378.15 KXS18851.1 - 8.2e-133 443.1 0.8 4.8e-132 440.6 0.5 2.3 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus IBN_N PF03810.19 KXS18851.1 - 5.1e-12 45.5 0.0 9.1e-11 41.5 0.0 3.0 2 1 0 2 2 2 1 Importin-beta N-terminal domain DUF3385 PF11865.8 KXS18851.1 - 0.028 14.3 0.2 0.47 10.3 0.0 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3385) Xpo1 PF08389.12 KXS18851.1 - 0.12 12.5 5.7 0.17 12.0 0.1 3.8 5 0 0 5 5 5 0 Exportin 1-like protein Peptidase_M24 PF00557.24 KXS18852.1 - 2.2e-16 60.2 0.0 3.7e-16 59.4 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 TFIIA PF03153.13 KXS18852.1 - 0.0021 18.1 18.3 0.0021 18.1 18.3 1.7 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit Mitofilin PF09731.9 KXS18852.1 - 0.35 9.7 9.5 0.64 8.8 9.5 1.3 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Presenilin PF01080.17 KXS18852.1 - 5.8 5.6 8.0 9.1 4.9 8.0 1.3 1 0 0 1 1 1 0 Presenilin Suf PF05843.14 KXS18852.1 - 9.6 6.1 20.0 9 6.2 18.5 1.6 1 1 0 1 1 1 0 Suppressor of forked protein (Suf) WD40 PF00400.32 KXS18853.1 - 4.1e-15 55.9 13.3 0.013 16.4 0.0 6.4 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXS18853.1 - 2.8e-13 50.0 0.0 1.6e-06 28.4 0.0 4.9 2 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain SDA1 PF05285.12 KXS18853.1 - 9.6 5.5 14.4 17 4.7 14.4 1.4 1 0 0 1 1 1 0 SDA1 B12D PF06522.11 KXS18854.1 - 2.4e-11 43.3 0.1 3.1e-11 42.9 0.1 1.2 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit Semialdhyde_dhC PF02774.18 KXS18856.1 - 4.1e-33 115.0 0.0 5.6e-33 114.6 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 KXS18856.1 - 2e-30 105.7 0.0 3.4e-30 105.0 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 KXS18856.1 - 0.0019 18.3 0.0 0.0036 17.4 0.0 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus DXP_reductoisom PF02670.16 KXS18856.1 - 0.029 15.1 0.3 0.066 13.9 0.0 1.8 2 0 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase TPH PF13868.6 KXS18857.1 - 2.5e-68 230.2 136.4 2.5e-68 230.2 136.4 2.0 2 0 0 2 2 2 1 Trichohyalin-plectin-homology domain TMEM43 PF07787.12 KXS18857.1 - 5.1 6.4 10.5 5.6 6.3 9.1 1.7 1 1 0 1 1 1 0 Transmembrane protein 43 Cyclin_N PF00134.23 KXS18858.1 - 3.9e-42 143.0 0.0 6.6e-42 142.3 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KXS18858.1 - 5.5e-19 68.4 0.0 8.4e-19 67.8 0.0 1.3 1 0 0 1 1 1 1 Cyclin, C-terminal domain ABC2_membrane PF01061.24 KXS18859.1 - 1.7e-30 106.0 23.7 1.7e-30 106.0 23.7 1.7 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 KXS18859.1 - 1.1e-24 87.5 0.1 1.9e-24 86.7 0.1 1.4 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 KXS18859.1 - 0.0021 18.5 0.1 0.0049 17.3 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 KXS18859.1 - 0.012 15.6 0.1 0.022 14.7 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_23 PF13476.6 KXS18859.1 - 0.034 14.7 0.1 0.054 14.0 0.1 1.3 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 KXS18859.1 - 0.035 13.5 1.0 0.36 10.2 1.0 2.0 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KXS18859.1 - 0.063 13.1 1.8 1.6 8.5 0.5 2.4 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 KXS18859.1 - 0.065 13.3 0.3 0.15 12.2 0.3 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase ABC2_membrane_3 PF12698.7 KXS18859.1 - 0.19 10.8 26.2 0.17 11.0 25.2 1.4 1 1 0 1 1 1 0 ABC-2 family transporter protein RGS PF00615.19 KXS18860.1 - 1.8e-05 25.0 0.0 2.9e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain MotA_ExbB PF01618.16 KXS18860.1 - 0.079 12.7 0.1 0.23 11.2 0.1 1.8 1 0 0 1 1 1 0 MotA/TolQ/ExbB proton channel family Fer2 PF00111.27 KXS18861.1 - 0.035 14.0 0.1 0.046 13.7 0.1 1.3 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain Pkinase PF00069.25 KXS18866.1 - 3.1e-66 223.4 0.0 3.7e-66 223.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS18866.1 - 7.5e-36 123.7 0.0 8.6e-36 123.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXS18866.1 - 9.5e-06 25.1 0.1 6.7e-05 22.4 0.0 2.2 1 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 KXS18866.1 - 2.8e-05 23.2 0.0 4e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KXS18866.1 - 0.00042 20.3 0.1 0.019 14.9 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 KXS18866.1 - 0.0053 16.4 0.5 0.14 11.7 0.0 2.1 1 1 1 2 2 2 1 RIO1 family Pkinase_fungal PF17667.1 KXS18866.1 - 0.012 14.4 0.0 0.014 14.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 KXS18866.1 - 0.043 13.2 0.0 0.061 12.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SAC3_GANP PF03399.16 KXS18868.1 - 2.7e-66 224.0 0.0 4e-66 223.4 0.0 1.2 1 0 0 1 1 1 1 SAC3/GANP family Myb_DNA-binding PF00249.31 KXS18869.1 - 0.0039 17.3 0.1 0.0058 16.8 0.1 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain PIH1 PF08190.12 KXS18870.1 - 4.2e-27 94.7 0.0 5.7e-27 94.2 0.0 1.1 1 0 0 1 1 1 1 PIH1 N-terminal domain PIH1_CS PF18201.1 KXS18870.1 - 1.5e-08 34.9 0.0 3.5e-08 33.7 0.0 1.7 1 0 0 1 1 1 1 PIH1 CS-like domain Exo_endo_phos PF03372.23 KXS18871.1 - 1.3e-17 64.1 0.1 2.3e-17 63.3 0.1 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-GRF PF06839.12 KXS18871.1 - 4.1e-08 33.2 2.6 9.8e-08 32.0 0.2 2.3 2 0 0 2 2 2 1 GRF zinc finger Spuma_A9PTase PF03539.14 KXS18871.1 - 0.024 14.8 0.0 0.045 13.9 0.0 1.4 1 0 0 1 1 1 0 Spumavirus aspartic protease (A9) BAR_2 PF10455.9 KXS18872.1 - 5.4e-35 120.9 1.1 4.3e-34 118.0 1.1 1.9 1 1 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 KXS18872.1 - 6.2e-28 98.1 0.4 1.3e-27 97.0 0.4 1.5 1 1 0 1 1 1 1 BAR domain BAR_3 PF16746.5 KXS18872.1 - 1.7e-05 24.7 0.3 3.2e-05 23.8 0.2 1.5 2 0 0 2 2 2 1 BAR domain of APPL family DUF4678 PF15727.5 KXS18872.1 - 0.011 15.0 0.1 0.011 15.0 0.1 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4678) Arfaptin PF06456.13 KXS18872.1 - 0.025 14.2 1.3 0.16 11.5 1.0 2.4 2 1 0 2 2 2 0 Arfaptin-like domain Dynamin_M PF01031.20 KXS18872.1 - 0.11 11.7 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 Dynamin central region Calpain_inhib PF00748.19 KXS18872.1 - 0.45 11.0 5.2 1.4 9.4 0.0 2.7 3 0 0 3 3 3 0 Calpain inhibitor tRNA_m1G_MT PF01746.21 KXS18873.1 - 3.8e-27 95.3 0.5 7.5e-27 94.3 0.5 1.5 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase ORC_WH_C PF18137.1 KXS18873.1 - 0.00042 20.4 1.3 0.00042 20.4 1.3 2.3 2 0 0 2 2 2 1 Origin recognition complex winged helix C-terminal DUF4208 PF13907.6 KXS18873.1 - 0.044 14.2 1.5 0.055 13.9 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4208) DNA_pol_phi PF04931.13 KXS18873.1 - 0.051 11.7 9.5 0.087 10.9 9.5 1.3 1 0 0 1 1 1 0 DNA polymerase phi BSP_II PF05432.11 KXS18873.1 - 6.2 6.4 16.6 0.58 9.8 12.0 1.6 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) LSM PF01423.22 KXS18874.1 - 1.7e-06 27.6 0.0 2.1e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KXS18874.1 - 2.1e-06 27.8 0.1 2.8e-06 27.4 0.1 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain L51_S25_CI-B8 PF05047.16 KXS18875.1 - 1.3e-13 50.7 0.0 1.7e-13 50.2 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Prok_Ub PF14454.6 KXS18875.1 - 0.16 11.6 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic Ubiquitin GATA PF00320.27 KXS18876.1 - 2.4e-17 62.3 3.9 4e-17 61.5 3.9 1.4 1 0 0 1 1 1 1 GATA zinc finger PAS_3 PF08447.12 KXS18876.1 - 2.7e-14 53.2 0.0 5e-14 52.4 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 KXS18876.1 - 1.1e-09 38.3 0.0 2e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 KXS18876.1 - 9.4e-07 29.0 0.0 1.8e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 KXS18876.1 - 1.7e-06 28.3 0.0 3.2e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_11 PF14598.6 KXS18876.1 - 0.036 14.2 0.0 0.07 13.3 0.0 1.5 1 0 0 1 1 1 0 PAS domain PAS_8 PF13188.7 KXS18876.1 - 0.038 14.0 0.0 0.079 13.0 0.0 1.5 1 0 0 1 1 1 0 PAS domain DZR PF12773.7 KXS18876.1 - 0.051 13.6 0.6 0.1 12.7 0.6 1.4 1 0 0 1 1 1 0 Double zinc ribbon zinc_ribbon_9 PF14369.6 KXS18876.1 - 0.051 13.8 0.7 0.11 12.8 0.7 1.5 1 0 0 1 1 1 0 zinc-ribbon Zn-ribbon_8 PF09723.10 KXS18876.1 - 0.052 13.7 0.9 0.096 12.8 0.9 1.4 1 0 0 1 1 1 0 Zinc ribbon domain Nudix_N_2 PF14803.6 KXS18876.1 - 0.14 12.1 2.0 0.27 11.2 2.0 1.4 1 0 0 1 1 1 0 Nudix N-terminal FBPase PF00316.20 KXS18877.1 - 2.2e-70 236.0 0.2 2.9e-70 235.6 0.2 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Inositol_P PF00459.25 KXS18877.1 - 0.05 13.1 0.0 0.11 12.0 0.0 1.5 2 0 0 2 2 2 0 Inositol monophosphatase family DEAD_2 PF06733.15 KXS18878.1 - 2.1e-56 190.3 0.0 3.4e-56 189.7 0.0 1.3 1 0 0 1 1 1 1 DEAD_2 HBB PF06777.11 KXS18878.1 - 4.9e-45 153.6 1.4 2.7e-40 138.1 0.4 2.4 2 0 0 2 2 2 2 Helical and beta-bridge domain Helicase_C_2 PF13307.6 KXS18878.1 - 1.4e-43 149.0 0.0 3e-43 148.0 0.0 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain ResIII PF04851.15 KXS18878.1 - 9.2e-07 29.0 0.1 1.7e-05 24.9 0.1 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KXS18878.1 - 0.0028 17.5 0.1 0.2 11.4 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_11 PF13086.6 KXS18878.1 - 0.006 16.4 0.0 0.0097 15.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain SNF2_N PF00176.23 KXS18878.1 - 0.0066 15.2 0.0 1.3 7.6 0.0 2.6 3 0 0 3 3 3 2 SNF2 family N-terminal domain YtxC PF08812.11 KXS18878.1 - 0.022 14.4 0.5 0.68 9.5 0.0 2.9 3 0 0 3 3 3 0 YtxC-like family DUF2075 PF09848.9 KXS18878.1 - 0.12 11.5 0.0 3.9 6.6 0.0 2.5 2 1 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 KXS18878.1 - 0.14 11.6 0.0 2.7 7.4 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein Ribosomal_L6e PF01159.19 KXS18880.1 - 1.3 9.6 7.0 2.3 8.8 7.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L6e FapA PF03961.13 KXS18880.1 - 1.9 7.0 9.0 2.7 6.5 9.0 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF2894 PF11445.8 KXS18880.1 - 2 8.9 11.5 4 7.9 11.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2894) Hamartin PF04388.12 KXS18880.1 - 7.1 5.2 10.1 10 4.7 10.1 1.1 1 0 0 1 1 1 0 Hamartin protein DnaJ PF00226.31 KXS18881.1 - 7.9e-19 67.5 0.3 1.4e-18 66.8 0.3 1.4 1 0 0 1 1 1 1 DnaJ domain Efg1 PF10153.9 KXS18882.1 - 1.5e-24 86.6 8.8 1.5e-24 86.6 8.8 2.5 2 0 0 2 2 2 1 rRNA-processing protein Efg1 Zw10 PF06248.13 KXS18883.1 - 1.3e-49 169.2 0.0 1.8e-49 168.7 0.0 1.1 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 Dsl1_C PF11989.8 KXS18883.1 - 1.9e-06 27.8 0.1 6.8e-06 25.9 0.0 1.9 2 0 0 2 2 2 1 Retrograde transport protein Dsl1 C terminal Cys_Met_Meta_PP PF01053.20 KXS18884.1 - 6.4e-141 469.3 0.0 7.2e-141 469.1 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 KXS18884.1 - 1e-09 38.2 0.2 1.8e-09 37.4 0.2 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 KXS18884.1 - 1.5e-08 34.1 0.2 2.4e-08 33.3 0.2 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 KXS18884.1 - 1.5e-08 34.3 0.1 2.8e-08 33.4 0.1 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II GDC-P PF02347.16 KXS18884.1 - 0.0021 17.0 0.0 0.0031 16.4 0.0 1.2 1 0 0 1 1 1 1 Glycine cleavage system P-protein ADH_zinc_N PF00107.26 KXS18884.1 - 0.0087 16.0 0.1 0.03 14.3 0.1 1.9 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Beta_elim_lyase PF01212.21 KXS18884.1 - 0.031 13.5 0.0 0.077 12.3 0.0 1.5 1 1 0 1 1 1 0 Beta-eliminating lyase Asparaginase_C PF17763.1 KXS18884.1 - 0.049 13.9 0.1 0.4 10.9 0.0 2.5 2 0 0 2 2 2 0 Glutaminase/Asparaginase C-terminal domain AP_endonuc_2 PF01261.24 KXS18884.1 - 0.11 11.9 0.0 2 7.8 0.0 2.4 2 1 0 2 2 2 0 Xylose isomerase-like TIM barrel NmrA PF05368.13 KXS18885.1 - 8.7e-11 41.8 0.0 1.4e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXS18885.1 - 0.027 14.4 0.0 0.061 13.2 0.0 1.6 1 1 0 1 1 1 0 NAD(P)H-binding SLBP_RNA_bind PF15247.6 KXS18886.1 - 8.8e-28 96.2 1.0 8.8e-28 96.2 1.0 2.1 2 0 0 2 2 2 1 Histone RNA hairpin-binding protein RNA-binding domain SAP25 PF15476.6 KXS18886.1 - 0.065 12.9 1.0 0.11 12.1 0.6 1.6 1 1 0 1 1 1 0 Histone deacetylase complex subunit SAP25 Zn_clus PF00172.18 KXS18887.1 - 5.2e-06 26.5 8.7 9.7e-06 25.6 8.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.25 KXS18887.1 - 0.0017 18.3 0.0 0.0034 17.4 0.0 1.5 1 0 0 1 1 1 1 PAS fold DUF1658 PF07871.11 KXS18887.1 - 0.29 11.2 1.7 1 9.4 1.7 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1658) JmjC PF02373.22 KXS18888.1 - 2.6e-43 147.1 0.2 4.8e-43 146.2 0.2 1.5 1 0 0 1 1 1 1 JmjC domain, hydroxylase JmjN PF02375.17 KXS18888.1 - 3.2e-08 33.4 0.0 7.1e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 jmjN domain Golgin_A5 PF09787.9 KXS18889.1 - 2.7e-05 23.8 40.8 0.00025 20.6 11.2 3.2 1 1 2 3 3 3 3 Golgin subfamily A member 5 KASH_CCD PF14662.6 KXS18889.1 - 0.00061 19.7 4.2 0.00061 19.7 4.2 3.8 2 1 1 3 3 3 2 Coiled-coil region of CCDC155 or KASH Tropomyosin PF00261.20 KXS18889.1 - 0.0049 16.3 52.4 0.007 15.8 7.1 4.4 1 1 3 4 4 4 2 Tropomyosin HALZ PF02183.18 KXS18889.1 - 0.025 14.8 0.8 0.025 14.8 0.8 5.6 4 2 2 6 6 6 0 Homeobox associated leucine zipper Filament PF00038.21 KXS18889.1 - 0.037 13.6 40.8 0.039 13.5 3.4 4.3 1 1 2 4 4 4 0 Intermediate filament protein ATG16 PF08614.11 KXS18889.1 - 0.27 11.4 61.8 0.24 11.6 15.2 5.0 2 1 4 6 6 6 0 Autophagy protein 16 (ATG16) Rootletin PF15035.6 KXS18889.1 - 0.31 11.1 45.5 1.5 8.8 6.2 5.2 2 1 3 5 5 5 0 Ciliary rootlet component, centrosome cohesion CENP-F_leu_zip PF10473.9 KXS18889.1 - 0.38 10.8 42.6 0.54 10.3 6.5 4.8 2 2 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ADIP PF11559.8 KXS18889.1 - 1.1 9.4 47.2 0.49 10.5 1.6 5.3 1 1 4 6 6 6 0 Afadin- and alpha -actinin-Binding HMMR_N PF15905.5 KXS18889.1 - 1.4 8.4 33.1 0.11 11.9 7.2 3.6 1 1 1 3 3 3 0 Hyaluronan mediated motility receptor N-terminal Spc7 PF08317.11 KXS18889.1 - 2.2 7.1 45.6 3 6.7 7.8 3.9 1 1 3 4 4 4 0 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 KXS18889.1 - 6.7 6.8 53.0 0.12 12.4 8.5 5.3 2 2 4 6 6 6 0 TPR/MLP1/MLP2-like protein GAS PF13851.6 KXS18889.1 - 8 5.7 39.1 2.2 7.6 14.6 3.9 1 1 3 4 4 4 0 Growth-arrest specific micro-tubule binding DUF16 PF01519.16 KXS18889.1 - 9.5 6.8 13.8 20 5.7 2.1 3.9 2 1 1 3 3 3 0 Protein of unknown function DUF16 F-box-like PF12937.7 KXS18890.1 - 1.8e-07 30.9 0.3 7.4e-07 29.0 0.3 2.1 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXS18890.1 - 0.014 15.2 0.0 0.048 13.6 0.0 1.9 1 0 0 1 1 1 0 F-box domain Cys_rich_KTR PF14205.6 KXS18890.1 - 0.16 11.8 1.3 0.23 11.3 0.2 1.8 2 0 0 2 2 2 0 Cysteine-rich KTR NAD_binding_8 PF13450.6 KXS18891.1 - 5.4e-06 26.5 0.0 1.6e-05 25.1 0.0 1.9 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXS18891.1 - 1.4e-05 24.8 0.0 0.00041 20.0 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 KXS18891.1 - 0.018 14.4 0.0 0.6 9.3 0.0 2.4 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.19 KXS18891.1 - 0.24 10.6 0.2 0.38 9.9 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain Fe-ADH PF00465.19 KXS18892.1 - 1.9e-114 382.3 0.1 2.1e-114 382.1 0.1 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 KXS18892.1 - 5e-14 52.6 0.7 4.4e-06 26.6 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase DUF4129 PF13559.6 KXS18892.1 - 0.2 11.9 0.1 0.46 10.8 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4129) HAP1_N PF04849.13 KXS18894.1 - 0.0078 15.4 5.5 0.011 15.0 5.5 1.1 1 0 0 1 1 1 1 HAP1 N-terminal conserved region eIF3_subunit PF08597.10 KXS18894.1 - 0.0084 16.0 1.1 0.01 15.7 1.1 1.1 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit MAD PF05557.13 KXS18894.1 - 0.022 13.2 4.7 0.031 12.7 4.7 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein bZIP_1 PF00170.21 KXS18894.1 - 0.057 13.5 17.8 0.26 11.4 13.2 2.3 1 1 1 2 2 2 0 bZIP transcription factor TSC22 PF01166.18 KXS18894.1 - 0.64 10.4 4.0 3.1 8.2 4.0 2.1 1 1 0 1 1 1 0 TSC-22/dip/bun family CCDC85 PF10226.9 KXS18894.1 - 1.2 8.8 6.4 3.9 7.1 6.5 1.5 1 1 1 2 2 2 0 CCDC85 family SIKE PF05769.11 KXS18894.1 - 2 8.3 8.9 86 3.0 8.9 2.2 1 1 0 1 1 1 0 SIKE family DUF5094 PF17015.5 KXS18894.1 - 5.7 7.0 5.6 13 5.8 5.6 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF5094) Apolipoprotein PF01442.18 KXS18895.1 - 0.00021 21.2 8.2 0.0004 20.3 8.2 1.5 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain ApoLp-III PF07464.11 KXS18895.1 - 0.051 13.7 9.6 1.2 9.2 7.8 2.7 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) RE_AlwI PF09491.10 KXS18895.1 - 0.12 11.1 0.6 0.37 9.5 0.7 1.6 2 0 0 2 2 2 0 AlwI restriction endonuclease Bacillus_HBL PF05791.11 KXS18895.1 - 0.7 9.7 5.1 13 5.6 0.0 3.1 3 1 0 4 4 4 0 Bacillus haemolytic enterotoxin (HBL) HisKA_3 PF07730.13 KXS18895.1 - 2.9 8.5 5.9 7.7 7.1 0.2 3.8 2 1 2 4 4 4 0 Histidine kinase YtxH PF12732.7 KXS18895.1 - 5.8 7.5 26.3 0.29 11.7 5.9 4.8 1 1 2 3 3 3 0 YtxH-like protein DivIVA PF05103.13 KXS18895.1 - 8.4 6.5 8.1 2.2 8.4 4.6 1.8 2 0 0 2 2 2 0 DivIVA protein Ras PF00071.22 KXS18896.1 - 1.1e-45 155.1 1.7 1.3e-45 154.9 1.7 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXS18896.1 - 7.2e-16 58.5 0.1 1.1e-15 57.9 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXS18896.1 - 2.4e-07 30.4 0.1 2.8e-07 30.2 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KXS18896.1 - 3.6e-07 29.9 0.5 1.5e-06 27.9 0.3 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 KXS18896.1 - 1.8e-05 24.3 0.5 0.00022 20.8 0.5 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KXS18896.1 - 0.00023 21.1 0.7 0.0037 17.2 0.2 2.1 1 1 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 KXS18896.1 - 0.00045 20.3 0.1 0.00074 19.6 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 KXS18896.1 - 0.00088 18.8 0.2 0.0013 18.2 0.2 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1_Xtn PF16897.5 KXS18896.1 - 0.0032 17.5 0.2 0.0059 16.6 0.2 1.5 1 1 0 1 1 1 1 C-terminal region of MMR_HSR1 domain AAA_14 PF13173.6 KXS18896.1 - 0.0056 16.7 0.2 0.0094 16.0 0.1 1.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KXS18896.1 - 0.094 13.1 0.0 0.11 12.9 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain SH3_9 PF14604.6 KXS18897.1 - 1.6e-05 24.6 0.1 3.1e-05 23.7 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXS18897.1 - 0.0006 19.4 0.0 0.0011 18.6 0.0 1.4 1 0 0 1 1 1 1 SH3 domain LapA_dom PF06305.11 KXS18897.1 - 0.44 10.4 1.6 0.68 9.8 0.2 1.9 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain DAGK_acc PF00609.19 KXS18898.1 - 9.4e-26 91.1 0.0 2.1e-13 50.9 0.0 2.2 2 0 0 2 2 2 2 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 KXS18898.1 - 2.6e-22 78.8 0.0 3.9e-22 78.2 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain C1_1 PF00130.22 KXS18898.1 - 9.6e-09 35.0 20.6 5.3e-06 26.2 5.2 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) DNA_RNApol_7kD PF03604.13 KXS18898.1 - 0.14 11.8 4.6 0.047 13.4 0.7 2.2 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit Desulfoferrod_N PF06397.12 KXS18898.1 - 4.3 7.1 5.5 17 5.1 5.5 2.0 1 0 0 1 1 1 0 Desulfoferrodoxin, N-terminal domain DZR PF12773.7 KXS18898.1 - 6.7 6.8 14.6 1.1 9.3 3.8 2.7 2 0 0 2 2 2 0 Double zinc ribbon Aha1_N PF09229.11 KXS18899.1 - 1.3e-33 116.1 0.1 2e-33 115.5 0.1 1.2 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 KXS18899.1 - 4.1e-24 85.2 0.1 6.8e-24 84.5 0.1 1.3 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein 2OG-FeII_Oxy_3 PF13640.6 KXS18900.1 - 1.1e-09 39.0 0.0 1.9e-09 38.3 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Pox_C4_C10 PF03336.13 KXS18900.1 - 0.017 14.3 0.0 0.023 13.8 0.0 1.3 1 1 0 1 1 1 0 Poxvirus C4/C10 protein MFS_1 PF07690.16 KXS18901.1 - 2.1e-36 125.6 33.5 2.1e-36 125.6 33.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KXS18901.1 - 1 8.2 15.0 0.34 9.7 0.2 4.0 3 1 2 5 5 5 0 MFS_1 like family Glyco_trans_1_3 PF13528.6 KXS18902.1 - 3.8e-05 23.1 0.0 0.19 10.9 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 1 Glyco_tran_28_C PF04101.16 KXS18902.1 - 0.011 15.7 0.0 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain DnaJ PF00226.31 KXS18903.1 - 7.1e-18 64.5 2.0 2.3e-17 62.8 2.0 2.0 1 0 0 1 1 1 1 DnaJ domain Rhomboid PF01694.22 KXS18904.1 - 1e-33 116.5 11.4 1e-33 116.5 11.4 2.1 3 0 0 3 3 3 1 Rhomboid family DUF2070 PF09843.9 KXS18904.1 - 0.99 7.6 4.4 1.5 7.1 4.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) YoqO PF14037.6 KXS18904.1 - 4.3 7.9 8.5 2.5 8.6 2.7 2.7 2 1 1 3 3 3 0 YoqO-like protein Urm1 PF09138.11 KXS18905.1 - 6.2e-35 119.5 0.0 6.8e-35 119.3 0.0 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.20 KXS18905.1 - 3.8e-05 24.3 0.0 4.8e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 ThiS family Pkinase PF00069.25 KXS18906.1 - 1.6e-76 257.2 0.0 1.9e-76 256.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS18906.1 - 8.5e-41 139.9 0.0 1.1e-40 139.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXS18906.1 - 2.9e-09 36.7 0.0 8.3e-06 25.3 0.0 2.1 1 1 1 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 KXS18906.1 - 4e-05 22.6 0.1 7.6e-05 21.7 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase Phasin PF05597.11 KXS18906.1 - 0.081 12.9 0.1 5.3 7.1 0.1 2.4 2 0 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) FTA2 PF13095.6 KXS18906.1 - 0.11 12.1 0.1 2.3 7.8 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 KXS18906.1 - 0.14 11.5 0.4 0.3 10.4 0.1 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family PPR PF01535.20 KXS18907.1 - 0.00052 20.1 3.8 5.1 7.6 0.0 5.1 6 0 0 6 6 6 3 PPR repeat KIAA1430 PF13879.6 KXS18908.1 - 1.1e-14 55.0 9.2 1.8e-13 51.1 8.6 2.6 3 0 0 3 3 3 1 KIAA1430 homologue POP1 PF06978.11 KXS18909.1 - 1.4e-33 116.7 17.7 6e-19 68.8 3.5 2.2 1 1 1 2 2 2 2 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.12 KXS18909.1 - 4.9e-26 90.9 0.0 1e-25 89.9 0.0 1.6 1 0 0 1 1 1 1 POPLD (NUC188) domain GCV_T_C PF08669.11 KXS18909.1 - 0.0026 17.6 0.0 0.0071 16.2 0.0 1.7 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain RNR_Alpha PF17975.1 KXS18910.1 - 8.8e-41 138.5 0.0 2e-40 137.4 0.0 1.6 1 0 0 1 1 1 1 Ribonucleotide reductase alpha domain Ribonuc_red_lgC PF02867.15 KXS18910.1 - 3.5e-11 42.3 0.0 0.0045 15.6 0.0 3.2 3 0 0 3 3 3 3 Ribonucleotide reductase, barrel domain DUF1690 PF07956.11 KXS18911.1 - 1.1e-14 55.0 0.8 6.3e-10 39.6 0.6 2.1 1 1 1 2 2 2 2 Protein of Unknown function (DUF1690) VirC1 PF07015.11 KXS18911.1 - 0.062 12.6 0.1 0.15 11.4 0.0 1.5 2 0 0 2 2 2 0 VirC1 protein UCH PF00443.29 KXS18912.1 - 2.3e-48 165.0 0.0 2.8e-48 164.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KXS18912.1 - 1.2e-10 41.5 1.1 2e-09 37.5 1.1 2.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 KXS18912.1 - 9.7e-10 38.1 0.0 2.7e-09 36.6 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin family LETM1 PF07766.13 KXS18913.1 - 9.4e-95 317.0 2.2 2e-94 315.9 2.2 1.6 1 0 0 1 1 1 1 LETM1-like protein EF-hand_7 PF13499.6 KXS18913.1 - 0.0095 16.4 0.3 0.072 13.5 0.1 2.5 2 0 0 2 2 2 1 EF-hand domain pair MCU PF04678.13 KXS18913.1 - 1.2 9.2 4.0 4.6 7.3 4.0 2.0 1 0 0 1 1 1 0 Mitochondrial calcium uniporter GNT-I PF03071.15 KXS18913.1 - 6.8 5.3 5.9 13 4.4 2.1 2.1 2 0 0 2 2 2 0 GNT-I family CytochromB561_N PF09786.9 KXS18915.1 - 2.4e-23 83.0 0.0 4e-23 82.2 0.0 1.3 1 1 0 1 1 1 1 Cytochrome B561, N terminal DSBA PF01323.20 KXS18916.1 - 4.6e-35 121.1 0.0 5.3e-35 121.0 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_3 PF13192.6 KXS18916.1 - 0.015 15.3 0.1 0.053 13.6 0.0 1.9 2 0 0 2 2 2 0 Thioredoxin domain Thioredoxin_2 PF13098.6 KXS18916.1 - 0.028 14.9 0.1 0.15 12.5 0.1 2.3 1 1 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_4 PF13462.6 KXS18916.1 - 0.14 12.3 0.0 0.35 11.0 0.0 1.8 2 1 0 2 2 2 0 Thioredoxin COG2 PF06148.11 KXS18917.1 - 0.0015 18.6 0.1 0.0025 17.9 0.1 1.4 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.11 KXS18917.1 - 0.043 13.9 0.0 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 Vps51/Vps67 Uteroglobin PF01099.17 KXS18917.1 - 0.13 12.6 0.0 0.25 11.7 0.0 1.4 1 0 0 1 1 1 0 Uteroglobin family Zw10 PF06248.13 KXS18918.1 - 5.1e-07 28.6 0.0 7.8e-07 28.0 0.0 1.2 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 MFS_1 PF07690.16 KXS18919.1 - 2.1e-53 181.5 22.0 2.1e-53 181.5 22.0 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXS18919.1 - 2.9e-14 52.8 8.9 2.9e-14 52.8 8.9 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KXS18919.1 - 5.5e-06 25.1 4.5 8.5e-06 24.5 4.5 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 KXS18919.1 - 0.00011 21.7 3.3 0.00011 21.7 3.3 2.2 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB MFS_3 PF05977.13 KXS18919.1 - 0.00044 18.8 3.3 0.00044 18.8 3.3 1.6 2 0 0 2 2 2 1 Transmembrane secretion effector MFS_2 PF13347.6 KXS18919.1 - 0.0059 15.2 0.7 0.0059 15.2 0.7 3.9 2 2 2 4 4 4 3 MFS/sugar transport protein MFS_1_like PF12832.7 KXS18919.1 - 0.016 14.1 6.7 0.4 9.5 4.5 2.3 2 0 0 2 2 2 0 MFS_1 like family CPP1-like PF11833.8 KXS18919.1 - 0.53 9.9 8.6 0.56 9.8 4.4 2.4 2 1 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like DUF1298 PF06974.13 KXS18922.1 - 1.3e-12 47.9 0.1 3.3e-12 46.6 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1298) WES_acyltransf PF03007.16 KXS18922.1 - 3.5e-07 30.3 0.2 5.7e-07 29.6 0.2 1.4 1 0 0 1 1 1 1 Wax ester synthase-like Acyl-CoA acyltransferase domain PapA_C PF16911.5 KXS18922.1 - 0.0023 18.0 0.1 1.4 9.0 0.0 2.5 2 0 0 2 2 2 2 Phthiocerol/phthiodiolone dimycocerosyl transferase C-terminus GcpE PF04551.14 KXS18923.1 - 0.19 10.8 0.0 0.29 10.2 0.0 1.2 1 0 0 1 1 1 0 GcpE protein YEATS PF03366.16 KXS18924.1 - 2e-16 59.7 0.1 3.1e-16 59.1 0.1 1.3 1 0 0 1 1 1 1 YEATS family efThoc1 PF11957.8 KXS18925.1 - 2.4e-76 257.4 0.0 6.1e-76 256.0 0.0 1.6 1 1 0 1 1 1 1 THO complex subunit 1 transcription elongation factor NICE-3 PF07406.11 KXS18927.1 - 5.5e-05 23.2 0.0 7e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 NICE-3 protein DUF4129 PF13559.6 KXS18927.1 - 0.00026 21.2 0.2 0.00046 20.4 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4129) CLASP_N PF12348.8 KXS18928.1 - 2.3e-31 109.1 0.0 1.2e-11 44.7 0.0 6.0 5 0 0 5 5 5 4 CLASP N terminal HEAT PF02985.22 KXS18928.1 - 4e-13 48.4 6.2 0.0097 16.1 0.1 10.1 10 0 0 10 10 10 3 HEAT repeat HEAT_2 PF13646.6 KXS18928.1 - 3.4e-09 37.0 8.2 1.6 9.2 0.0 9.0 7 4 2 9 9 9 3 HEAT repeats Cnd1 PF12717.7 KXS18928.1 - 2.2e-07 31.0 8.9 1.8 8.6 0.0 7.8 7 1 1 8 8 8 2 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 KXS18928.1 - 7.6e-06 26.1 1.5 0.61 10.3 0.0 6.6 7 0 0 7 7 7 1 Required for nuclear transport of RNA pol II C-terminus 1 Vac14_Fab1_bd PF12755.7 KXS18928.1 - 0.0002 21.9 0.2 5.7 7.6 0.0 5.3 5 0 0 5 5 5 1 Vacuolar 14 Fab1-binding region TAN PF11640.8 KXS18928.1 - 0.00029 21.0 8.3 2.4 8.3 0.0 6.2 6 0 0 6 6 6 2 Telomere-length maintenance and DNA damage repair HEAT_EZ PF13513.6 KXS18928.1 - 0.0047 17.4 6.5 59 4.3 0.0 7.3 7 0 0 7 7 7 0 HEAT-like repeat DNA_pol3_delta PF06144.13 KXS18928.1 - 0.18 11.5 1.4 4.1 7.2 0.0 3.3 3 0 0 3 3 3 0 DNA polymerase III, delta subunit Abhydrolase_1 PF00561.20 KXS18930.1 - 0.0036 17.0 0.0 0.06 13.0 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold EHN PF06441.12 KXS18931.1 - 1.5e-30 105.8 0.0 2.6e-30 105.0 0.0 1.4 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KXS18931.1 - 6.3e-16 58.8 0.0 6.5e-15 55.5 0.0 2.3 3 0 0 3 3 3 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXS18931.1 - 0.13 12.9 2.9 0.11 13.1 1.0 2.0 2 1 0 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 KXS18932.1 - 4.4e-31 108.4 0.0 6.1e-31 107.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXS18932.1 - 0.00042 21.0 3.6 0.00074 20.2 3.6 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Say1_Mug180 PF10340.9 KXS18932.1 - 0.0035 16.3 0.0 0.0066 15.4 0.0 1.3 1 1 0 1 1 1 1 Steryl acetyl hydrolase COesterase PF00135.28 KXS18932.1 - 0.04 12.8 0.5 0.096 11.5 0.5 1.5 1 1 0 1 1 1 0 Carboxylesterase family DUF2974 PF11187.8 KXS18932.1 - 0.17 11.4 0.0 0.31 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) dCMP_cyt_deam_1 PF00383.23 KXS18933.1 - 1.2e-12 47.5 0.0 1.7e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KXS18933.1 - 3.9e-11 42.9 0.0 5.1e-11 42.5 0.0 1.1 1 0 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 KXS18933.1 - 3.2 7.8 4.3 28 4.8 1.5 2.1 1 1 1 2 2 2 0 Bd3614-like deaminase LIM PF00412.22 KXS18935.1 - 2.7e-09 37.1 1.6 3.8e-09 36.6 1.6 1.2 1 0 0 1 1 1 1 LIM domain 4HBT_3 PF13622.6 KXS18936.1 - 1.6e-13 51.5 0.0 1.5e-12 48.3 0.0 2.1 1 1 0 1 1 1 1 Thioesterase-like superfamily DUF3123 PF11321.8 KXS18937.1 - 0.62 10.8 2.8 1.1 9.9 2.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3123) Sulfate_transp PF00916.20 KXS18938.1 - 4.1e-48 164.1 24.9 6.1e-48 163.5 24.9 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KXS18938.1 - 0.005 16.5 0.0 0.01 15.5 0.0 1.4 1 0 0 1 1 1 1 STAS domain LRR_4 PF12799.7 KXS18939.1 - 6.2e-17 61.4 11.6 0.0017 18.7 0.0 6.4 6 1 0 7 7 7 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXS18939.1 - 2.8e-07 30.2 10.8 0.28 11.0 0.1 5.4 4 1 1 5 5 5 4 Leucine rich repeat SH3_1 PF00018.28 KXS18939.1 - 2.8e-06 26.9 0.0 5.1e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 SH3 domain LRR_1 PF00560.33 KXS18939.1 - 0.012 16.1 4.5 89 4.3 0.0 6.5 7 0 0 7 7 7 0 Leucine Rich Repeat Podoplanin PF05808.11 KXS18939.1 - 0.033 14.3 2.7 0.09 12.9 2.7 1.7 1 0 0 1 1 1 0 Podoplanin Trp_oprn_chp PF09534.10 KXS18939.1 - 0.052 13.3 0.6 0.1 12.4 0.6 1.4 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Gram_pos_anchor PF00746.21 KXS18939.1 - 0.069 13.1 2.6 0.16 12.0 0.5 2.7 2 0 0 2 2 2 0 LPXTG cell wall anchor motif SH3_9 PF14604.6 KXS18939.1 - 0.12 12.2 0.0 0.36 10.7 0.0 1.9 1 0 0 1 1 1 0 Variant SH3 domain PC4 PF02229.16 KXS18940.1 - 3.4e-22 77.8 0.2 5.1e-22 77.3 0.2 1.3 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) DUF3498 PF12004.8 KXS18942.1 - 0.91 8.6 7.8 1 8.5 7.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3498) zf-met PF12874.7 KXS18942.1 - 0.98 9.9 3.7 4.7 7.8 0.1 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KXS18942.1 - 1.6 9.8 20.1 0.14 13.0 2.4 3.5 3 1 0 3 3 3 0 C2H2-type zinc finger MFS_1 PF07690.16 KXS18943.1 - 1e-28 100.3 70.9 3.4e-23 82.2 38.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KXS18943.1 - 7.6e-06 24.7 23.0 7.6e-06 24.7 23.0 2.8 1 1 1 2 2 2 2 MFS/sugar transport protein EB PF01683.18 KXS18944.1 - 0.0018 18.5 10.0 0.0029 17.9 10.0 1.3 1 0 0 1 1 1 1 EB module YwiC PF14256.6 KXS18944.1 - 0.057 13.7 2.1 0.42 10.9 1.5 2.0 2 0 0 2 2 2 0 YwiC-like protein TMEM43 PF07787.12 KXS18944.1 - 0.17 11.2 1.1 0.25 10.7 1.1 1.1 1 0 0 1 1 1 0 Transmembrane protein 43 Cellulase PF00150.18 KXS18945.1 - 5e-12 45.8 5.8 9e-12 45.0 0.7 2.6 2 1 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Excalibur PF05901.11 KXS18945.1 - 0.014 16.0 4.8 6 7.6 0.1 4.2 4 0 0 4 4 4 0 Excalibur calcium-binding domain ADH_N_2 PF16884.5 KXS18946.1 - 2.1e-23 82.3 0.0 3.9e-23 81.4 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 KXS18946.1 - 8e-21 74.4 0.0 1.4e-20 73.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXS18946.1 - 5.7e-08 33.9 0.1 2.4e-07 31.9 0.0 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase PGM_PMM_II PF02879.16 KXS18946.1 - 0.046 14.3 0.1 0.28 11.8 0.0 2.2 2 0 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II DUF5122 PF17164.4 KXS18946.1 - 2.1 8.7 4.7 3 8.2 0.0 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF5122) beta-propeller Ferric_reduct PF01794.19 KXS18948.1 - 2.7e-19 69.5 6.2 2.7e-19 69.5 6.2 2.0 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KXS18948.1 - 4.4e-18 65.9 0.0 3.2e-09 37.1 0.0 2.2 1 1 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KXS18948.1 - 5.2e-14 52.2 0.0 1e-13 51.3 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 KXS18948.1 - 0.00028 21.5 0.0 0.0026 18.4 0.0 2.2 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KXS18948.1 - 0.11 12.9 0.0 0.23 11.9 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain Reeler PF02014.16 KXS18949.1 - 7e-18 65.6 0.1 1.2e-09 39.0 0.0 2.3 2 0 0 2 2 2 2 Reeler domain zf-C2H2 PF00096.26 KXS18951.1 - 0.39 11.3 18.2 0.32 11.5 3.6 3.6 3 1 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXS18951.1 - 2.3 9.3 17.4 4.2 8.5 3.2 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KXS18952.1 - 1 9.9 15.6 2.5 8.7 1.6 3.2 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_11 PF16622.5 KXS18952.1 - 1.5 8.6 6.0 0.36 10.6 1.4 2.1 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_4 PF13894.6 KXS18952.1 - 3.6 8.7 18.9 1.7 9.7 1.7 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger DUF3576 PF12100.8 KXS18953.1 - 0.15 12.2 0.0 15 5.8 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3576) AAA_5 PF07728.14 KXS18954.1 - 2.6e-111 367.6 0.1 1.2e-22 80.4 0.0 9.7 9 0 0 9 9 9 9 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 KXS18954.1 - 2.4e-42 143.4 8.4 4.4e-14 52.6 0.1 6.7 6 0 0 6 6 6 3 Midasin AAA lid domain AAA_3 PF07726.11 KXS18954.1 - 9.9e-29 99.8 0.0 1.2e-10 41.4 0.0 6.9 8 0 0 8 8 6 4 ATPase family associated with various cellular activities (AAA) AAA_lid_5 PF17865.1 KXS18954.1 - 3.5e-26 91.3 0.1 3.5e-26 91.3 0.1 3.1 4 0 0 4 4 2 1 Midasin AAA lid domain AAA PF00004.29 KXS18954.1 - 4.7e-24 85.3 0.7 0.0077 16.7 0.0 7.1 6 0 0 6 6 6 5 ATPase family associated with various cellular activities (AAA) Dynein_heavy PF03028.15 KXS18954.1 - 1.2e-23 83.4 0.0 0.00018 21.6 0.0 7.2 7 0 0 7 7 7 5 Dynein heavy chain region D6 P-loop domain AAA_6 PF12774.7 KXS18954.1 - 3.1e-21 75.7 0.4 0.00026 20.1 0.1 7.2 7 1 0 7 7 7 4 Hydrolytic ATP binding site of dynein motor region AAA_7 PF12775.7 KXS18954.1 - 1.1e-19 70.6 3.9 0.00018 21.1 0.0 6.9 7 0 0 7 7 6 4 P-loop containing dynein motor region AAA_18 PF13238.6 KXS18954.1 - 3.3e-17 63.2 1.8 0.22 12.1 0.0 7.1 6 0 0 6 6 6 4 AAA domain AAA_16 PF13191.6 KXS18954.1 - 6.8e-16 59.1 21.4 0.024 15.0 0.0 9.3 7 3 0 8 8 7 4 AAA ATPase domain Sigma54_activat PF00158.26 KXS18954.1 - 1.3e-15 57.5 1.7 0.0014 18.4 0.0 6.0 7 0 0 7 7 5 4 Sigma-54 interaction domain AAA_30 PF13604.6 KXS18954.1 - 1e-12 48.2 1.3 0.024 14.3 0.1 8.5 8 0 0 8 8 8 1 AAA domain AAA_22 PF13401.6 KXS18954.1 - 4.9e-12 46.3 3.5 0.51 10.6 0.0 7.9 7 0 0 7 7 6 3 AAA domain ABC_tran PF00005.27 KXS18954.1 - 2.2e-10 41.2 8.4 0.0027 18.2 0.0 6.8 8 0 0 8 8 5 2 ABC transporter T2SSE PF00437.20 KXS18954.1 - 3.7e-10 39.3 1.0 0.03 13.4 0.0 6.0 7 0 0 7 7 6 2 Type II/IV secretion system protein AAA_14 PF13173.6 KXS18954.1 - 6.7e-10 39.1 0.0 0.0086 16.1 0.0 6.4 7 0 0 7 7 5 1 AAA domain TsaE PF02367.17 KXS18954.1 - 1.2e-09 38.2 5.3 0.0036 17.3 0.1 5.8 6 0 0 6 6 5 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_29 PF13555.6 KXS18954.1 - 4.9e-09 35.8 1.5 0.14 11.9 0.0 5.2 5 0 0 5 5 5 2 P-loop containing region of AAA domain AAA_28 PF13521.6 KXS18954.1 - 1.5e-08 35.1 3.5 2.6 8.2 0.0 7.0 7 0 0 7 7 6 1 AAA domain AAA_33 PF13671.6 KXS18954.1 - 1.7e-08 34.8 1.9 2.8 8.1 0.0 6.5 6 0 0 6 6 5 1 AAA domain Sigma54_activ_2 PF14532.6 KXS18954.1 - 2.8e-08 34.0 0.1 0.0099 16.0 0.0 4.2 4 0 0 4 4 3 2 Sigma-54 interaction domain AAA_23 PF13476.6 KXS18954.1 - 2.2e-07 31.6 8.7 0.1 13.1 0.0 6.0 6 0 0 6 6 4 2 AAA domain Zeta_toxin PF06414.12 KXS18954.1 - 2.8e-07 30.0 2.9 0.88 8.8 0.1 6.3 6 0 0 6 6 6 1 Zeta toxin Mg_chelatase PF01078.21 KXS18954.1 - 3.4e-07 29.9 1.7 8.8 5.7 0.0 7.4 8 0 0 8 8 8 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 KXS18954.1 - 3.7e-07 30.5 2.3 13 6.2 0.0 6.7 6 0 0 6 6 6 0 RNA helicase AAA_19 PF13245.6 KXS18954.1 - 1e-06 29.2 8.9 0.25 11.7 0.2 6.2 7 1 0 7 7 5 2 AAA domain AAA_25 PF13481.6 KXS18954.1 - 1.5e-06 27.9 2.7 0.9 9.1 0.0 6.0 6 0 0 6 6 5 1 AAA domain RsgA_GTPase PF03193.16 KXS18954.1 - 1.9e-06 27.9 2.8 2.1 8.2 0.0 5.7 6 0 0 6 6 5 1 RsgA GTPase PduV-EutP PF10662.9 KXS18954.1 - 7.3e-05 22.5 2.7 0.72 9.6 0.0 4.9 5 0 0 5 5 5 1 Ethanolamine utilisation - propanediol utilisation RuvB_N PF05496.12 KXS18954.1 - 9.6e-05 22.2 3.2 7.6 6.3 0.0 6.0 7 0 0 7 7 6 0 Holliday junction DNA helicase RuvB P-loop domain NACHT PF05729.12 KXS18954.1 - 0.00016 21.6 7.2 2.2 8.2 0.1 5.7 6 0 0 6 6 6 1 NACHT domain Rad17 PF03215.15 KXS18954.1 - 0.00022 21.2 1.1 3.2 7.7 0.0 4.7 5 0 0 5 5 4 1 Rad17 P-loop domain DUF815 PF05673.13 KXS18954.1 - 0.00039 19.7 1.1 1 8.4 0.0 4.0 5 0 0 5 5 4 1 Protein of unknown function (DUF815) AAA_24 PF13479.6 KXS18954.1 - 0.00039 20.2 2.2 18 5.0 0.0 6.1 6 0 0 6 6 6 0 AAA domain Roc PF08477.13 KXS18954.1 - 0.0014 18.8 5.8 22 5.3 0.0 5.6 6 0 0 6 6 5 0 Ras of Complex, Roc, domain of DAPkinase Viral_helicase1 PF01443.18 KXS18954.1 - 0.0017 18.2 1.6 12 5.5 0.1 5.5 6 0 0 6 6 5 0 Viral (Superfamily 1) RNA helicase SRP54 PF00448.22 KXS18954.1 - 0.0039 16.9 2.5 2.6 7.6 0.2 4.1 4 0 0 4 4 3 1 SRP54-type protein, GTPase domain ATPase_2 PF01637.18 KXS18954.1 - 0.0051 16.8 0.1 27 4.6 0.0 5.0 6 0 0 6 6 5 0 ATPase domain predominantly from Archaea TniB PF05621.11 KXS18954.1 - 0.0076 15.7 0.1 41 3.5 0.0 4.2 4 0 0 4 4 4 0 Bacterial TniB protein VWA_2 PF13519.6 KXS18954.1 - 0.009 16.6 0.0 0.033 14.9 0.0 2.1 1 0 0 1 1 1 1 von Willebrand factor type A domain SRPRB PF09439.10 KXS18954.1 - 0.018 14.5 1.4 20 4.6 0.0 4.3 5 0 0 5 5 4 0 Signal recognition particle receptor beta subunit AAA_8 PF12780.7 KXS18954.1 - 0.019 14.3 4.1 3.3 7.0 0.0 4.9 6 0 0 6 6 6 0 P-loop containing dynein motor region D4 DEAD PF00270.29 KXS18954.1 - 0.022 14.5 0.3 22 4.7 0.1 3.7 3 0 0 3 3 3 0 DEAD/DEAH box helicase cobW PF02492.19 KXS18954.1 - 0.031 13.9 1.1 45 3.6 0.1 4.1 4 0 0 4 4 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.6 KXS18954.1 - 0.037 14.4 4.8 4.7 7.6 0.2 4.9 4 0 0 4 4 4 0 AAA domain MMR_HSR1 PF01926.23 KXS18954.1 - 0.042 13.9 7.5 29 4.8 0.0 5.5 6 0 0 6 6 5 0 50S ribosome-binding GTPase NTPase_1 PF03266.15 KXS18954.1 - 0.06 13.2 11.3 16 5.3 0.1 5.4 6 0 0 6 6 4 0 NTPase ATP_bind_1 PF03029.17 KXS18954.1 - 0.076 12.8 10.8 0.43 10.3 0.0 5.8 6 0 0 6 6 5 0 Conserved hypothetical ATP binding protein ATPase PF06745.13 KXS18954.1 - 0.13 11.6 2.1 21 4.4 0.0 4.2 4 0 0 4 4 4 0 KaiC CPT PF07931.12 KXS18954.1 - 0.17 11.7 4.3 1.1e+02 2.5 0.1 6.0 5 1 0 5 5 5 0 Chloramphenicol phosphotransferase-like protein Torus PF16131.5 KXS18955.1 - 5.2e-28 97.9 0.4 9.5e-28 97.1 0.4 1.5 1 0 0 1 1 1 1 Torus domain RRM_1 PF00076.22 KXS18955.1 - 4.1e-07 29.7 0.1 7.3e-07 28.9 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KXS18955.1 - 0.00019 21.4 0.1 0.00037 20.4 0.1 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif zf_CCCH_4 PF18345.1 KXS18955.1 - 0.18 11.9 4.1 0.37 10.9 4.1 1.6 1 0 0 1 1 1 0 Zinc finger domain RAI1 PF08652.11 KXS18956.1 - 3.2e-22 78.5 0.0 7.6e-22 77.3 0.0 1.7 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease Tim17 PF02466.19 KXS18958.1 - 2e-20 73.2 6.7 3.1e-20 72.6 6.7 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family ABC_membrane PF00664.23 KXS18959.1 - 6.9e-70 235.8 22.1 2.2e-40 139.1 1.0 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KXS18959.1 - 1.7e-50 171.1 0.0 5.3e-28 98.3 0.0 2.6 2 0 0 2 2 2 2 ABC transporter MMR_HSR1 PF01926.23 KXS18959.1 - 7e-06 26.1 0.9 0.15 12.2 0.1 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase SMC_N PF02463.19 KXS18959.1 - 9.4e-06 25.2 7.5 0.58 9.6 0.2 4.0 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KXS18959.1 - 3.4e-05 23.5 0.5 0.064 13.0 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KXS18959.1 - 0.00011 22.1 0.1 0.27 11.1 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_21 PF13304.6 KXS18959.1 - 0.00016 21.6 7.1 0.1 12.4 0.1 4.9 3 3 2 5 5 5 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KXS18959.1 - 0.00053 20.4 0.3 0.1 12.9 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_7 PF12775.7 KXS18959.1 - 0.0017 17.9 0.2 2.1 7.8 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region Zeta_toxin PF06414.12 KXS18959.1 - 0.0027 17.0 0.0 0.13 11.5 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_25 PF13481.6 KXS18959.1 - 0.0029 17.2 0.1 0.089 12.4 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_23 PF13476.6 KXS18959.1 - 0.0059 17.1 0.0 5.5 7.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 KXS18959.1 - 0.0069 16.1 0.1 0.83 9.3 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 KXS18959.1 - 0.007 16.1 0.3 3.2 7.4 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 KXS18959.1 - 0.011 16.0 1.4 1.6 9.0 0.0 3.4 2 1 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 KXS18959.1 - 0.039 14.0 4.8 0.074 13.1 0.2 2.5 2 0 0 2 2 2 0 Dynamin family T2SSE PF00437.20 KXS18959.1 - 0.044 12.9 0.0 0.28 10.2 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein Roc PF08477.13 KXS18959.1 - 0.054 13.7 0.1 13 6.0 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase DUF815 PF05673.13 KXS18959.1 - 0.068 12.3 0.2 6.5 5.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) cobW PF02492.19 KXS18959.1 - 0.11 12.0 0.8 0.75 9.4 0.1 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.22 KXS18959.1 - 0.18 11.0 0.6 6.1 6.0 0.0 2.5 2 1 0 2 2 2 0 NB-ARC domain DUF87 PF01935.17 KXS18959.1 - 0.95 9.5 2.4 2.3 8.3 0.3 2.2 2 0 0 2 2 2 0 Helicase HerA, central domain EF-hand_7 PF13499.6 KXS18960.1 - 1.4e-06 28.7 4.0 6.9e-06 26.4 0.5 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 KXS18960.1 - 5.6e-05 22.8 2.9 0.0053 16.6 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 KXS18960.1 - 0.0001 21.6 7.2 0.0033 16.9 0.2 3.2 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 KXS18960.1 - 0.028 14.2 3.1 0.038 13.8 0.7 2.3 1 1 1 2 2 2 0 EF-hand domain pair EF-hand_5 PF13202.6 KXS18960.1 - 0.061 12.8 6.6 1.2 8.7 0.1 3.2 3 0 0 3 3 3 0 EF hand RE_Eco47II PF09553.10 KXS18960.1 - 0.082 12.5 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 Eco47II restriction endonuclease RasGEF PF00617.19 KXS18962.1 - 6.1e-50 169.9 0.0 7.6e-50 169.6 0.0 1.1 1 0 0 1 1 1 1 RasGEF domain ABC_tran_Xtn PF12848.7 KXS18962.1 - 0.17 11.9 0.5 0.54 10.3 0.0 1.9 2 0 0 2 2 2 0 ABC transporter DnaGprimase_HBD PF16730.5 KXS18962.1 - 0.23 11.5 0.0 0.34 11.0 0.0 1.2 1 0 0 1 1 1 0 DnaG-primase C-terminal, helicase-binding domain Pex19 PF04614.12 KXS18963.1 - 9.8e-46 156.5 0.2 1.2e-45 156.2 0.2 1.1 1 0 0 1 1 1 1 Pex19 protein family zf-ZPR1 PF03367.13 KXS18964.1 - 2.9e-109 362.0 0.0 2.9e-54 183.2 0.1 2.2 2 0 0 2 2 2 2 ZPR1 zinc-finger domain DZR PF12773.7 KXS18964.1 - 0.0036 17.3 2.8 0.17 11.9 0.3 3.0 3 0 0 3 3 3 1 Double zinc ribbon zinc-ribbons_6 PF07191.12 KXS18964.1 - 0.19 11.7 3.0 0.71 9.9 0.1 2.4 2 1 0 2 2 2 0 zinc-ribbons zf-ribbon_3 PF13248.6 KXS18964.1 - 2.9 7.4 9.6 5.2 6.6 0.1 3.5 3 0 0 3 3 3 0 zinc-ribbon domain FA_hydroxylase PF04116.13 KXS18965.1 - 1.4e-17 64.3 15.6 1.4e-17 64.3 15.6 1.8 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily zf-C2H2_6 PF13912.6 KXS18966.1 - 1.2e-06 28.3 0.7 0.00066 19.6 0.6 2.2 1 1 1 2 2 2 2 C2H2-type zinc finger zf-C2H2_4 PF13894.6 KXS18966.1 - 8.6e-06 26.2 1.6 0.013 16.3 0.1 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KXS18966.1 - 1.5e-05 25.2 1.9 0.048 14.1 0.1 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KXS18966.1 - 0.0025 18.1 3.5 0.025 14.8 0.4 2.2 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding Ima1_N PF09779.9 KXS18966.1 - 0.023 15.6 0.3 0.033 15.1 0.3 1.2 1 0 0 1 1 1 0 Ima1 N-terminal domain LIM PF00412.22 KXS18966.1 - 0.078 13.2 1.8 0.14 12.4 1.8 1.4 1 0 0 1 1 1 0 LIM domain zf-Di19 PF05605.12 KXS18966.1 - 0.24 11.7 2.1 1.3 9.4 1.9 2.1 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding DSPc PF00782.20 KXS18967.1 - 7.7e-27 93.7 0.0 1e-26 93.3 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KXS18967.1 - 0.014 15.0 0.0 0.017 14.7 0.0 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Ala_racemase_N PF01168.20 KXS18968.1 - 1.5e-19 70.5 0.0 2.2e-19 70.0 0.0 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain D-ser_dehydrat PF14031.6 KXS18968.1 - 8e-16 58.5 0.0 1.7e-15 57.5 0.0 1.6 1 0 0 1 1 1 1 Putative serine dehydratase domain LEM PF03020.15 KXS18968.1 - 0.11 12.0 1.0 0.21 11.2 0.0 1.9 2 0 0 2 2 2 0 LEM domain RTA1 PF04479.13 KXS18969.1 - 1e-51 175.5 14.0 1e-51 175.5 14.0 1.3 2 0 0 2 2 2 1 RTA1 like protein UL42 PF17638.2 KXS18969.1 - 2 8.4 6.0 19 5.3 0.4 3.0 3 0 0 3 3 3 0 HCMV UL42 PhoLip_ATPase_C PF16212.5 KXS18969.1 - 5.3 6.7 21.0 3.7 7.2 7.5 2.1 1 1 1 2 2 2 0 Phospholipid-translocating P-type ATPase C-terminal zf-H2C2_2 PF13465.6 KXS18972.1 - 2.3e-15 56.2 14.8 2.6e-07 30.8 3.6 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 KXS18972.1 - 7.9e-15 54.4 16.8 2.1e-06 27.8 0.6 3.3 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXS18972.1 - 3.8e-13 49.0 15.1 0.00063 20.4 5.5 3.3 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KXS18972.1 - 4e-07 30.2 4.5 0.16 12.3 0.0 3.2 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KXS18972.1 - 5.5e-05 23.1 14.1 0.023 14.7 0.1 3.2 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.7 KXS18972.1 - 7.1e-05 23.1 7.2 0.017 15.5 0.1 3.3 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 KXS18972.1 - 0.0092 16.3 4.5 0.062 13.6 5.1 1.8 1 1 1 2 2 2 2 C2H2-type zinc ribbon zf-C2H2_3rep PF18868.1 KXS18972.1 - 0.14 12.8 3.9 2.4 8.8 0.6 2.2 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats GAGA PF09237.11 KXS18972.1 - 0.2 11.5 2.2 0.27 11.1 0.9 1.8 1 1 1 2 2 2 0 GAGA factor zf-C2H2_11 PF16622.5 KXS18972.1 - 0.32 10.8 7.9 0.41 10.5 0.1 3.1 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-BED PF02892.15 KXS18972.1 - 0.43 10.6 6.2 18 5.5 3.7 2.9 2 1 1 3 3 3 0 BED zinc finger C1_4 PF07975.12 KXS18972.1 - 1.7 9.0 6.4 17 5.7 6.5 2.1 1 1 1 2 2 2 0 TFIIH C1-like domain Myticin-prepro PF10690.9 KXS18973.1 - 0.26 11.5 7.5 0.3 11.3 7.5 1.2 1 0 0 1 1 1 0 Myticin pre-proprotein from the mussel 2-Hacid_dh_C PF02826.19 KXS18974.1 - 4.2e-56 189.1 0.0 5.1e-56 188.8 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KXS18974.1 - 3e-05 23.7 0.0 9.7e-05 22.0 0.0 1.7 1 1 2 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KXS18974.1 - 0.00011 22.5 0.2 0.00015 22.0 0.2 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 KXS18974.1 - 0.09 12.7 0.3 0.15 11.9 0.3 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Glyco_hydro_28 PF00295.17 KXS18975.1 - 1e-14 54.4 1.9 1.1e-14 54.2 1.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Linker_histone PF00538.19 KXS18976.1 - 5.2e-19 68.4 0.1 7.3e-19 67.9 0.1 1.2 1 0 0 1 1 1 1 linker histone H1 and H5 family ARL2_Bind_BART PF11527.8 KXS18976.1 - 0.082 13.0 0.1 0.11 12.6 0.1 1.2 1 0 0 1 1 1 0 The ARF-like 2 binding protein BART Forkhead PF00250.18 KXS18976.1 - 0.082 13.2 0.0 0.1 12.9 0.0 1.2 1 0 0 1 1 1 0 Forkhead domain DUF5345 PF17280.2 KXS18977.1 - 0.016 15.2 1.4 0.031 14.3 1.4 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5345) Cation_ATPase_C PF00689.21 KXS18977.1 - 0.024 14.3 0.2 0.032 14.0 0.2 1.2 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus STE3 PF02076.15 KXS18977.1 - 0.04 13.1 0.9 0.049 12.8 0.9 1.1 1 0 0 1 1 1 0 Pheromone A receptor Hydrolase PF00702.26 KXS18978.1 - 3.6e-10 40.5 0.0 4.9e-10 40.0 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KXS18978.1 - 6.3e-10 39.4 0.0 1e-09 38.7 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Aminotran_1_2 PF00155.21 KXS18979.1 - 2.8e-22 79.4 0.0 3.5e-22 79.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II EHN PF06441.12 KXS18980.1 - 3.4e-18 66.0 0.0 6.4e-18 65.1 0.0 1.5 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KXS18980.1 - 3.1e-16 59.8 0.1 5.1e-16 59.1 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXS18980.1 - 0.0002 22.0 8.7 0.00031 21.4 5.3 2.6 2 1 0 2 2 2 1 Alpha/beta hydrolase family bZIP_1 PF00170.21 KXS18981.1 - 3.4e-11 43.1 12.5 5.2e-11 42.5 12.5 1.3 1 0 0 1 1 1 1 bZIP transcription factor Zwint PF15556.6 KXS18981.1 - 0.0017 17.9 6.2 0.0019 17.8 6.2 1.0 1 0 0 1 1 1 1 ZW10 interactor SHE3 PF17078.5 KXS18981.1 - 0.0035 17.1 5.5 0.0036 17.1 5.5 1.0 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 bZIP_2 PF07716.15 KXS18981.1 - 0.0053 16.8 8.9 0.0053 16.8 8.9 2.0 1 1 1 2 2 2 1 Basic region leucine zipper BRE1 PF08647.11 KXS18981.1 - 0.011 15.8 7.1 0.011 15.8 7.1 1.0 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase Glutaredoxin2_C PF04399.13 KXS18981.1 - 0.027 14.3 1.0 0.03 14.1 1.0 1.0 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain XhlA PF10779.9 KXS18981.1 - 0.047 13.9 5.5 0.067 13.4 5.5 1.2 1 0 0 1 1 1 0 Haemolysin XhlA DUF641 PF04859.12 KXS18981.1 - 0.048 14.0 5.8 0.049 14.0 5.8 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Vac_Fusion PF02346.16 KXS18981.1 - 0.086 12.5 3.7 0.11 12.1 3.4 1.3 1 1 0 1 1 1 0 Chordopoxvirus multifunctional envelope protein A27 bZIP_Maf PF03131.17 KXS18981.1 - 0.1 13.2 9.8 0.12 12.9 9.8 1.1 1 0 0 1 1 1 0 bZIP Maf transcription factor M PF02370.16 KXS18981.1 - 0.51 11.1 5.0 3.7 8.4 0.3 3.0 1 1 1 2 2 2 0 M protein repeat Tho2 PF11262.8 KXS18981.1 - 1.3 8.2 7.1 1.3 8.1 7.1 1.0 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DivIC PF04977.15 KXS18981.1 - 1.3 8.8 5.5 3.6 7.4 5.5 1.8 1 1 0 1 1 1 0 Septum formation initiator p450 PF00067.22 KXS18985.1 - 9.5e-21 74.1 0.0 1.5e-20 73.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 BST2 PF16716.5 KXS18985.1 - 0.21 12.2 0.0 0.34 11.5 0.0 1.2 1 0 0 1 1 1 0 Bone marrow stromal antigen 2 CATSPERG PF15064.6 KXS18988.1 - 1.9e-15 55.8 0.0 2.8e-15 55.3 0.0 1.1 1 0 0 1 1 1 1 Cation channel sperm-associated protein subunit gamma DUF202 PF02656.15 KXS18989.1 - 8.9e-16 58.1 2.1 8.9e-16 58.1 2.1 2.0 3 0 0 3 3 3 1 Domain of unknown function (DUF202) DUF1206 PF06724.11 KXS18989.1 - 1.5 9.0 5.8 4.2 7.5 0.7 3.1 3 1 0 3 3 3 0 Domain of Unknown Function (DUF1206) Thioredoxin_4 PF13462.6 KXS18990.1 - 0.023 14.9 0.0 0.065 13.4 0.0 1.7 1 1 0 1 1 1 0 Thioredoxin NblA PF04485.12 KXS18990.1 - 0.081 13.3 1.3 0.098 13.1 0.2 1.7 2 0 0 2 2 2 0 Phycobilisome degradation protein nblA DUF3606 PF12244.8 KXS18990.1 - 0.11 12.4 0.2 0.26 11.3 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) Penicil_amidase PF01804.18 KXS18991.1 - 1.2e-168 563.2 0.0 1.3e-168 563.1 0.0 1.0 1 0 0 1 1 1 1 Penicillin amidase DUF3602 PF12223.8 KXS18992.1 - 3.4 8.3 6.8 0.29 11.8 1.0 2.2 2 2 1 3 3 3 0 Protein of unknown function (DUF3602) Oxidored_molyb PF00174.19 KXS18993.1 - 4e-40 137.2 0.0 8.9e-40 136.1 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 KXS18993.1 - 5.8e-33 113.8 0.6 1.2e-32 112.8 0.6 1.5 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain NAD_binding_1 PF00175.21 KXS18993.1 - 2.4e-21 76.4 0.0 5.5e-21 75.3 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.28 KXS18993.1 - 2.9e-21 75.4 0.0 5.2e-21 74.6 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FAD_binding_6 PF00970.24 KXS18993.1 - 1.1e-19 70.6 0.0 2.2e-19 69.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KXS18993.1 - 1.7e-06 28.2 0.0 9.9e-05 22.5 0.0 2.3 1 1 1 2 2 2 1 Ferric reductase NAD binding domain SPX PF03105.19 KXS18994.1 - 3.7 7.4 13.6 0.15 12.0 8.1 1.4 2 0 0 2 2 2 0 SPX domain GST_N_3 PF13417.6 KXS18995.1 - 4.1e-10 39.9 0.0 7.2e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KXS18995.1 - 1.8e-05 25.0 0.0 3.6e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KXS18995.1 - 3.5e-05 23.7 0.2 7.4e-05 22.7 0.2 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 KXS18995.1 - 0.06 14.1 0.0 0.38 11.5 0.0 2.2 2 1 0 2 2 2 0 Glutathione S-transferase N-terminal domain GST_C_3 PF14497.6 KXS18995.1 - 0.11 12.7 0.0 0.19 12.0 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain MFS_1 PF07690.16 KXS18996.1 - 5.1e-24 84.8 41.0 5.1e-20 71.7 43.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2663 PF10864.8 KXS18996.1 - 6.2 7.2 5.7 0.6 10.5 0.1 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2663) AAA PF00004.29 KXS18997.1 - 1.8e-19 70.4 0.0 3.3e-19 69.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KXS18997.1 - 3.8e-05 23.5 0.0 6.5e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KXS18997.1 - 0.00025 21.5 0.0 0.00071 20.0 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 KXS18997.1 - 0.00033 20.7 0.0 0.008 16.2 0.0 2.3 1 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_11 PF13086.6 KXS18997.1 - 0.00063 19.6 0.0 0.0011 18.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KXS18997.1 - 0.0014 19.2 0.0 0.0095 16.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.11 KXS18997.1 - 0.0016 18.3 0.0 0.0031 17.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BCS1_N PF08740.11 KXS18997.1 - 0.0017 18.4 0.2 0.0039 17.2 0.1 1.6 2 0 0 2 2 2 1 BCS1 N terminal AAA_22 PF13401.6 KXS18997.1 - 0.0025 18.1 0.0 0.011 16.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 KXS18997.1 - 0.0032 17.1 0.1 0.38 10.3 0.0 2.4 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.13 KXS18997.1 - 0.0067 15.6 0.0 0.061 12.5 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_30 PF13604.6 KXS18997.1 - 0.014 15.1 0.0 0.027 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Zot PF05707.12 KXS18997.1 - 0.025 14.2 0.1 6.6 6.3 0.0 2.6 2 1 1 3 3 3 0 Zonular occludens toxin (Zot) AAA_19 PF13245.6 KXS18997.1 - 0.026 14.9 0.0 0.046 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 KXS18997.1 - 0.026 13.7 0.0 0.039 13.2 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain Hydin_ADK PF17213.3 KXS18997.1 - 0.11 12.8 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain RNA_helicase PF00910.22 KXS18997.1 - 0.14 12.5 0.0 0.33 11.4 0.0 1.6 1 0 0 1 1 1 0 RNA helicase DNA_pol_phi PF04931.13 KXS18997.1 - 1.5 6.8 5.7 1.9 6.5 5.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi S-methyl_trans PF02574.16 KXS18999.1 - 1.2e-61 208.9 0.0 1.5e-61 208.6 0.0 1.1 1 0 0 1 1 1 1 Homocysteine S-methyltransferase LRR_6 PF13516.6 KXS19001.1 - 1e-09 37.6 3.2 0.51 10.5 0.1 7.2 8 0 0 8 8 8 3 Leucine Rich repeat F-box-like PF12937.7 KXS19001.1 - 1.6e-05 24.7 0.7 5.3e-05 23.0 0.7 1.9 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KXS19001.1 - 0.00037 20.8 0.0 3.5 8.2 0.0 4.0 3 1 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KXS19001.1 - 0.0018 18.5 2.1 26 5.9 0.0 5.6 6 0 0 6 6 6 1 Leucine Rich Repeat DUF4778 PF16008.5 KXS19002.1 - 0.061 13.4 0.4 0.07 13.2 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) Phage_holin_2_4 PF16082.5 KXS19002.1 - 0.08 12.7 0.5 0.2 11.4 0.5 1.7 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like SLATT_1 PF18181.1 KXS19002.1 - 0.17 11.8 0.1 0.17 11.8 0.1 2.1 3 0 0 3 3 3 0 SMODS and SLOG-associating 2TM effector domain 1 Polysacc_deac_1 PF01522.21 KXS19003.1 - 2e-32 111.7 0.0 3.1e-32 111.1 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 KXS19003.1 - 0.041 13.1 0.0 0.055 12.7 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 Pectinesterase PF01095.19 KXS19004.1 - 1.3e-10 40.5 0.1 1.5e-10 40.3 0.1 1.0 1 0 0 1 1 1 1 Pectinesterase Glyco_hydro_28 PF00295.17 KXS19005.1 - 7.5e-70 235.5 11.3 1.1e-69 235.1 11.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.6 KXS19005.1 - 0.0017 18.2 23.1 0.0017 18.2 23.1 2.8 1 1 1 2 2 2 2 Right handed beta helix region Rrf2 PF02082.20 KXS19005.1 - 0.06 13.7 0.1 0.12 12.8 0.1 1.4 1 0 0 1 1 1 0 Transcriptional regulator Galanin PF01296.18 KXS19005.1 - 0.29 11.1 0.2 0.29 11.1 0.2 2.3 3 0 0 3 3 3 0 Galanin NT-C2 PF10358.9 KXS19006.1 - 3.5e-17 62.5 0.0 5.3e-17 61.9 0.0 1.2 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins U-box PF04564.15 KXS19007.1 - 3.8e-23 81.4 0.1 1.1e-22 80.0 0.0 1.8 2 0 0 2 2 2 1 U-box domain CHIP_TPR_N PF18391.1 KXS19007.1 - 3.1e-12 47.1 1.6 5.3e-12 46.3 1.6 1.4 1 0 0 1 1 1 1 CHIP N-terminal tetratricopeptide repeat domain TPR_1 PF00515.28 KXS19007.1 - 4e-11 42.2 0.5 9.3e-06 25.3 0.1 3.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KXS19007.1 - 1.8e-10 40.1 0.5 0.003 17.5 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 KXS19007.1 - 1.4e-08 34.3 0.2 4.1e-05 23.2 0.0 3.0 3 0 0 3 3 3 2 TPR repeat TPR_16 PF13432.6 KXS19007.1 - 0.00029 21.4 1.1 0.031 14.9 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KXS19007.1 - 0.0013 19.4 0.0 0.13 13.2 0.0 2.9 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 KXS19007.1 - 0.0022 18.2 2.7 0.16 12.3 0.6 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KXS19007.1 - 0.0025 17.9 0.1 0.62 10.4 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 KXS19007.1 - 0.0045 16.9 0.5 6 7.1 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 KXS19007.1 - 0.0066 16.8 0.2 0.036 14.4 0.0 2.3 3 0 0 3 3 3 1 Tetratricopeptide repeat Copper-bind PF00127.20 KXS19008.1 - 9.2e-10 38.9 0.6 1.8e-09 37.9 0.6 1.5 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Cu_bind_like PF02298.17 KXS19008.1 - 0.015 15.3 0.2 0.026 14.5 0.2 1.4 1 0 0 1 1 1 0 Plastocyanin-like domain Cu-oxidase_3 PF07732.15 KXS19008.1 - 0.099 12.7 1.8 0.16 12.0 1.8 1.5 1 1 0 1 1 1 0 Multicopper oxidase NUDIX_4 PF14815.6 KXS19009.1 - 0.044 13.8 0.0 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 NUDIX domain Ras PF00071.22 KXS19010.1 - 4.6e-51 172.6 0.0 5.2e-51 172.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXS19010.1 - 1.7e-22 79.9 0.0 2.2e-22 79.5 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXS19010.1 - 2.9e-06 26.8 0.0 6.3e-06 25.7 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KXS19010.1 - 0.00089 18.7 0.0 0.0012 18.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 KXS19010.1 - 0.0063 16.9 0.0 0.0087 16.5 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain Gtr1_RagA PF04670.12 KXS19010.1 - 0.079 12.3 0.0 0.092 12.1 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Abhydrolase_1 PF00561.20 KXS19011.1 - 4.9e-16 59.1 0.0 1.6e-14 54.2 0.1 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXS19011.1 - 8.6e-14 52.7 1.5 8.6e-14 52.7 1.5 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXS19011.1 - 4.8e-09 35.8 0.0 2.1e-08 33.7 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KXS19011.1 - 0.055 12.9 0.1 9.9 5.6 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family HCV_NS4a PF01006.20 KXS19012.1 - 0.27 11.0 2.2 0.29 10.9 0.2 2.1 2 0 0 2 2 2 0 Hepatitis C virus non-structural protein NS4a Polysacc_deac_1 PF01522.21 KXS19013.1 - 2.7e-29 101.6 0.0 3.2e-29 101.4 0.0 1.0 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 KXS19013.1 - 0.046 12.9 0.0 0.049 12.8 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 Polysacc_deac_1 PF01522.21 KXS19014.1 - 4.5e-19 68.6 0.0 7.3e-19 67.9 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 KXS19014.1 - 0.00039 19.7 0.0 0.00047 19.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 UEV PF05743.13 KXS19015.1 - 1.2e-18 67.1 0.1 2.4e-18 66.1 0.1 1.5 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.10 KXS19015.1 - 4.2e-10 39.4 0.0 9.8e-10 38.2 0.0 1.6 1 0 0 1 1 1 1 Vps23 core domain UQ_con PF00179.26 KXS19015.1 - 0.027 14.1 0.3 0.058 13.0 0.3 1.5 1 0 0 1 1 1 0 Ubiquitin-conjugating enzyme S6OS1 PF15676.5 KXS19015.1 - 0.098 11.1 0.1 0.13 10.7 0.1 1.1 1 0 0 1 1 1 0 Six6 opposite strand transcript 1 family RWD PF05773.22 KXS19015.1 - 0.19 12.0 0.5 0.4 11.0 0.5 1.5 1 0 0 1 1 1 0 RWD domain AAA PF00004.29 KXS19016.1 - 4.6e-17 62.7 0.0 6.8e-17 62.1 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KXS19016.1 - 5e-05 23.3 0.0 8.6e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 KXS19016.1 - 0.00061 19.2 0.3 0.2 11.0 0.2 2.2 1 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_lid_6 PF17866.1 KXS19016.1 - 0.0022 18.1 0.2 0.0051 17.0 0.2 1.6 1 0 0 1 1 1 1 AAA lid domain AAA_22 PF13401.6 KXS19016.1 - 0.0025 18.1 0.0 0.14 12.4 0.0 2.5 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 KXS19016.1 - 0.0031 17.3 0.0 0.014 15.1 0.0 1.9 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activat PF00158.26 KXS19016.1 - 0.0041 16.9 0.1 0.54 9.9 0.1 2.2 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_30 PF13604.6 KXS19016.1 - 0.015 15.0 0.0 0.084 12.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KXS19016.1 - 0.066 12.5 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_16 PF13191.6 KXS19016.1 - 0.23 11.8 1.5 0.35 11.2 0.0 2.1 3 0 0 3 3 3 0 AAA ATPase domain Ole-e-6 PF09253.10 KXS19018.1 - 0.025 14.5 2.1 0.043 13.8 2.1 1.4 1 0 0 1 1 1 0 Pollen allergen ole e 6 SH3_9 PF14604.6 KXS19019.1 - 6e-05 22.8 0.1 9.8e-05 22.1 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXS19019.1 - 0.00017 21.1 0.0 0.00027 20.5 0.0 1.3 1 0 0 1 1 1 1 SH3 domain Sugar_tr PF00083.24 KXS19020.1 - 7.2e-98 328.4 22.7 9.5e-98 328.0 22.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXS19020.1 - 1.2e-15 57.4 37.3 2.5e-11 43.1 12.6 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily Abhydrolase_3 PF07859.13 KXS19022.1 - 1.4e-32 113.3 0.0 2.2e-32 112.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KXS19022.1 - 1.1e-12 47.6 0.0 1.6e-12 47.0 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Chlorophyllase2 PF12740.7 KXS19022.1 - 0.0015 17.5 0.0 0.0027 16.7 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Peptidase_S9 PF00326.21 KXS19022.1 - 0.0022 17.5 0.1 0.0088 15.5 0.0 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family BAAT_C PF08840.11 KXS19022.1 - 0.0029 17.5 0.0 0.0074 16.2 0.0 1.6 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal AXE1 PF05448.12 KXS19022.1 - 0.03 13.0 0.0 0.044 12.5 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Copine PF07002.16 KXS19023.1 - 1.5e-64 217.5 0.0 2.1e-64 216.9 0.0 1.2 1 0 0 1 1 1 1 Copine C2 PF00168.30 KXS19023.1 - 2.2e-19 69.6 0.0 1.2e-09 38.4 0.0 2.4 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.9 KXS19023.1 - 0.037 14.1 0.0 0.064 13.4 0.0 1.3 1 0 0 1 1 1 0 vWA found in TerF C terminus RTA1 PF04479.13 KXS19024.1 - 1.7e-51 174.7 10.0 2.7e-51 174.1 10.0 1.3 1 0 0 1 1 1 1 RTA1 like protein DUF4436 PF14494.6 KXS19026.1 - 0.00014 21.2 0.0 0.00017 21.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4436) DUF4436 PF14494.6 KXS19027.1 - 7.7e-10 38.5 1.0 9.6e-10 38.2 1.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4436) SH3_9 PF14604.6 KXS19028.1 - 5.5e-06 26.1 0.0 9.3e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain Glyco_hydro_3_C PF01915.22 KXS19029.1 - 2.7e-53 181.0 0.0 4.8e-53 180.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KXS19029.1 - 6.5e-44 150.6 0.0 9.6e-44 150.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KXS19029.1 - 1.8e-18 66.4 0.0 4e-18 65.3 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain BDV_P24 PF06595.11 KXS19030.1 - 0.22 11.4 0.0 0.31 10.9 0.0 1.2 1 0 0 1 1 1 0 Borna disease virus P24 protein Epimerase PF01370.21 KXS19031.1 - 4.8e-19 68.8 0.6 4.8e-17 62.2 0.1 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXS19031.1 - 6.6e-17 61.4 0.0 1.5e-16 60.2 0.0 1.5 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KXS19031.1 - 1.3e-13 51.3 0.0 1.7e-13 50.9 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KXS19031.1 - 3.9e-13 49.5 0.1 5.6e-13 49.0 0.1 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KXS19031.1 - 3.9e-09 36.1 0.7 9.2e-09 34.8 0.7 1.6 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.13 KXS19031.1 - 1.7e-06 27.8 0.0 7.5e-06 25.7 0.0 1.9 2 0 0 2 2 2 1 NmrA-like family KR PF08659.10 KXS19031.1 - 0.00052 20.0 0.5 0.0012 18.8 0.5 1.5 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KXS19031.1 - 0.0071 15.5 0.1 0.011 15.0 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KXS19031.1 - 0.072 12.2 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain Ank_2 PF12796.7 KXS19032.1 - 1.1e-08 35.6 3.2 0.25 11.9 0.0 5.2 2 1 4 6 6 6 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXS19032.1 - 2.9e-05 24.5 0.4 4.6 7.9 0.0 4.9 4 1 0 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXS19032.1 - 0.0014 18.9 0.9 1.7e+02 3.3 0.0 6.3 7 0 0 7 7 7 0 Ankyrin repeat DUF829 PF05705.14 KXS19033.1 - 3.6e-07 30.3 0.0 0.007 16.3 0.0 3.1 3 0 0 3 3 3 3 Eukaryotic protein of unknown function (DUF829) Ank_3 PF13606.6 KXS19034.1 - 0.002 18.5 0.0 2.6 8.9 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 KXS19034.1 - 0.14 12.7 0.0 0.22 12.2 0.0 1.3 1 1 0 1 1 1 0 Ankyrin repeats (many copies) Macoilin PF09726.9 KXS19035.1 - 0.53 8.8 1.2 0.57 8.7 1.2 1.2 1 0 0 1 1 1 0 Macoilin family DUF1387 PF07139.11 KXS19035.1 - 1.7 8.3 4.6 2.4 7.8 4.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) SOG2 PF10428.9 KXS19035.1 - 5.4 6.1 20.7 7 5.7 20.7 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Amino_oxidase PF01593.24 KXS19036.1 - 9.9e-64 216.3 0.1 1.2e-63 216.1 0.1 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KXS19036.1 - 2.7e-14 53.1 1.0 6.5e-14 51.9 1.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KXS19036.1 - 9.7e-07 28.2 0.1 0.0013 17.9 0.0 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein FAD_binding_2 PF00890.24 KXS19036.1 - 6.1e-06 25.6 3.3 1.1e-05 24.8 3.3 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KXS19036.1 - 0.00013 20.8 3.7 0.00046 19.0 1.8 2.2 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 KXS19036.1 - 0.00016 21.0 0.9 0.00016 21.0 0.9 1.5 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.14 KXS19036.1 - 0.00024 20.4 4.6 0.0012 18.1 1.0 2.2 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXS19036.1 - 0.00025 20.7 7.6 0.00044 19.9 7.6 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KXS19036.1 - 0.00027 21.4 2.3 0.0024 18.4 1.3 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KXS19036.1 - 0.0021 17.2 2.0 0.0021 17.2 2.0 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 KXS19036.1 - 0.0024 17.3 9.2 0.007 15.8 9.1 1.9 1 1 1 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KXS19036.1 - 0.0044 16.3 2.5 0.008 15.5 2.5 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 KXS19036.1 - 0.0066 15.7 0.7 0.0066 15.7 0.7 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KXS19036.1 - 0.022 14.0 4.0 0.054 12.8 4.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ChitinaseA_N PF08329.10 KXS19036.1 - 0.029 14.0 0.4 0.052 13.2 0.4 1.5 1 0 0 1 1 1 0 Chitinase A, N-terminal domain NAD_binding_9 PF13454.6 KXS19036.1 - 3 7.8 4.8 31 4.5 0.5 2.7 3 0 0 3 3 3 0 FAD-NAD(P)-binding NAD_binding_4 PF07993.12 KXS19037.1 - 1.4e-32 112.9 0.0 1.8e-32 112.5 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 KXS19037.1 - 9.1e-05 22.0 0.3 0.00022 20.8 0.3 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KXS19037.1 - 0.00018 21.7 0.4 0.033 14.4 0.1 2.7 3 0 0 3 3 3 1 Saccharopine dehydrogenase NADP binding domain GDP_Man_Dehyd PF16363.5 KXS19037.1 - 0.016 14.6 0.0 0.025 14.0 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KXS19037.1 - 0.019 14.0 0.0 0.059 12.4 0.0 1.8 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KXS19037.1 - 0.019 14.8 0.4 0.04 13.8 0.4 1.6 1 1 0 1 1 1 0 NAD(P)H-binding Semialdhyde_dh PF01118.24 KXS19037.1 - 0.027 14.9 0.1 0.14 12.6 0.0 2.3 3 0 0 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain HI0933_like PF03486.14 KXS19037.1 - 0.091 11.4 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Cyclin_N PF00134.23 KXS19039.1 - 7e-28 96.9 0.0 2.7e-26 91.8 0.0 2.1 2 0 0 2 2 2 2 Cyclin, N-terminal domain SET PF00856.28 KXS19040.1 - 0.0091 16.4 0.1 0.52 10.7 0.1 3.0 1 1 0 1 1 1 1 SET domain 4HBT_3 PF13622.6 KXS19042.1 - 4.7e-07 30.3 0.3 5.2e-07 30.2 0.3 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily MoaC PF01967.21 KXS19043.1 - 2.7e-41 140.8 0.0 6.2e-41 139.7 0.0 1.6 1 1 0 1 1 1 1 MoaC family Mob_synth_C PF06463.13 KXS19043.1 - 8.4e-31 106.6 0.0 1.3e-30 106.0 0.0 1.3 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 KXS19043.1 - 2e-24 86.9 0.0 3.8e-24 86.0 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 KXS19043.1 - 2.6e-06 27.7 0.0 4.7e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 KXS19043.1 - 0.012 15.8 0.6 0.037 14.2 0.1 2.0 2 1 0 2 2 2 0 4Fe-4S single cluster domain DUF1768 PF08719.11 KXS19044.1 - 4.5e-52 176.5 0.0 5.6e-52 176.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Phage_30_3 PF08010.11 KXS19044.1 - 0.051 13.4 0.0 0.28 11.0 0.0 2.0 1 1 0 1 1 1 0 Bacteriophage protein GP30.3 Glyco_hydro_28 PF00295.17 KXS19045.1 - 9.1e-78 261.6 19.2 1.1e-77 261.3 19.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Glyco_hydro_28 PF00295.17 KXS19046.1 - 2.9e-52 177.7 17.6 2.3e-45 155.1 12.2 2.0 1 1 1 2 2 2 2 Glycosyl hydrolases family 28 2OG-FeII_Oxy PF03171.20 KXS19048.1 - 1.3e-21 77.0 0.0 2.6e-21 76.0 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 KXS19048.1 - 3.6e-20 72.9 0.0 6e-20 72.2 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal DUF4203 PF13886.6 KXS19049.1 - 2.9e-18 66.3 17.9 5.3e-18 65.4 17.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) Holin_2-3 PF13272.6 KXS19049.1 - 0.067 13.5 0.6 0.2 12.0 0.1 2.0 1 1 1 2 2 2 0 Putative 2/3 transmembrane domain holin PRA1 PF03208.19 KXS19049.1 - 3.2 7.4 10.6 0.5 10.0 6.9 1.5 2 0 0 2 2 2 0 PRA1 family protein DUF4282 PF14110.6 KXS19049.1 - 7.6 7.3 14.8 6.4 7.6 4.8 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4282) Glyco_hydro_28 PF00295.17 KXS19050.1 - 3.4e-78 263.0 22.0 4.1e-78 262.7 22.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Spermine_synth PF01564.17 KXS19050.1 - 0.06 12.7 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Spermine/spermidine synthase domain Ank PF00023.30 KXS19051.1 - 0.082 13.4 0.0 0.2 12.2 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeat Glyco_hydro_79C PF16862.5 KXS19052.1 - 2.8e-07 31.4 0.0 5.4e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain GFA PF04828.14 KXS19053.1 - 7.1e-13 48.7 1.7 9.9e-13 48.3 1.7 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Tho2 PF11262.8 KXS19054.1 - 0.16 11.2 3.4 0.29 10.3 0.0 2.2 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 Adaptin_binding PF10199.9 KXS19054.1 - 0.26 11.9 0.1 0.26 11.9 0.1 2.5 2 1 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 DUF4140 PF13600.6 KXS19054.1 - 0.88 10.0 0.0 0.88 10.0 0.0 5.1 4 2 1 5 5 5 0 N-terminal domain of unknown function (DUF4140) HOOK PF05622.12 KXS19054.1 - 4.1 5.4 28.0 14 3.7 28.0 1.7 1 1 0 1 1 1 0 HOOK protein ubiquitin PF00240.23 KXS19055.1 - 3.9e-26 90.6 0.0 5e-26 90.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KXS19055.1 - 1.5e-11 43.9 0.0 2.1e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ZZ PF00569.17 KXS19055.1 - 7.5e-11 41.7 5.8 1.5e-10 40.8 5.8 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type TBK1_ULD PF18396.1 KXS19055.1 - 0.00021 21.2 0.0 0.00031 20.6 0.0 1.2 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_2 PF14560.6 KXS19055.1 - 0.012 16.0 0.0 0.032 14.7 0.0 1.7 1 1 0 1 1 1 0 Ubiquitin-like domain Ubiquitin_4 PF18036.1 KXS19055.1 - 0.18 11.9 0.0 2.1 8.5 0.0 2.0 2 0 0 2 2 2 0 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 KXS19055.1 - 0.19 11.8 0.0 0.32 11.1 0.0 1.4 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Peptidase_M1 PF01433.20 KXS19056.1 - 6.8e-69 231.8 0.0 2.3e-68 230.0 0.0 1.8 1 1 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 KXS19056.1 - 6.5e-51 173.7 0.0 1.6e-50 172.5 0.0 1.6 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 KXS19056.1 - 3.4e-46 157.8 0.0 6e-46 157.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Aminopep PF10023.9 KXS19056.1 - 0.083 12.2 0.1 0.17 11.2 0.1 1.4 1 0 0 1 1 1 0 Putative aminopeptidase Peptidase_M48 PF01435.18 KXS19056.1 - 0.14 11.9 0.0 0.4 10.4 0.0 1.7 2 0 0 2 2 2 0 Peptidase family M48 Glyco_hydro_31 PF01055.26 KXS19057.1 - 1e-149 499.5 0.0 1.2e-149 499.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 KXS19057.1 - 2e-16 60.2 0.5 3e-15 56.4 0.5 2.3 1 1 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 KXS19057.1 - 2e-10 40.9 0.1 7.2e-10 39.0 0.0 2.1 2 0 0 2 2 2 1 Galactose mutarotase-like Trefoil PF00088.18 KXS19057.1 - 3.3e-10 39.7 31.2 7.9e-08 32.1 7.1 3.2 4 0 0 4 4 4 2 Trefoil (P-type) domain Exo_endo_phos PF03372.23 KXS19058.1 - 9.4e-18 64.6 0.2 1.2e-17 64.2 0.2 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Pkinase PF00069.25 KXS19059.1 - 4.1e-78 262.4 0.0 5.3e-78 262.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS19059.1 - 8.8e-46 156.3 0.0 1.1e-45 155.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXS19059.1 - 3.8e-10 39.6 0.0 5.3e-10 39.1 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KXS19059.1 - 1.1e-05 24.5 0.0 1.7e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 KXS19059.1 - 3.2e-05 23.6 1.3 7.1e-05 22.5 0.4 1.8 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.14 KXS19059.1 - 0.00024 20.5 1.0 0.00055 19.3 1.0 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXS19059.1 - 0.013 15.4 0.1 1.8 8.5 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family ACD PF16671.5 KXS19059.1 - 0.021 13.1 0.1 0.039 12.3 0.1 1.4 1 0 0 1 1 1 0 Actin cross-linking domain YrbL-PhoP_reg PF10707.9 KXS19059.1 - 0.1 12.1 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL KA1 PF02149.19 KXS19060.1 - 4.1e-18 64.9 0.1 6.1e-18 64.4 0.1 1.3 1 0 0 1 1 1 1 Kinase associated domain 1 SET PF00856.28 KXS19061.1 - 6.4e-20 72.2 0.1 7.7e-19 68.7 0.1 1.9 1 1 0 1 1 1 1 SET domain AWS PF17907.1 KXS19062.1 - 0.0017 18.3 0.3 0.0039 17.2 0.3 1.5 1 0 0 1 1 1 1 AWS domain VIT1 PF01988.19 KXS19065.1 - 2.5e-60 204.0 2.7 2.9e-60 203.8 2.7 1.0 1 0 0 1 1 1 1 VIT family SLATT_fungal PF18142.1 KXS19065.1 - 0.13 12.3 0.9 0.21 11.6 0.0 1.9 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 7tm_2 PF00002.24 KXS19067.1 - 0.0011 18.3 0.0 0.0017 17.7 0.0 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) GSIII_N PF12437.8 KXS19069.1 - 3e-63 212.2 0.0 5.9e-63 211.3 0.0 1.5 1 0 0 1 1 1 1 Glutamine synthetase type III N terminal Gln-synt_C-ter PF18318.1 KXS19069.1 - 2.9e-40 136.8 0.6 6.5e-40 135.7 0.6 1.6 1 0 0 1 1 1 1 Glutamine synthetase C-terminal domain Gln-synt_C PF00120.24 KXS19069.1 - 2.2e-16 59.8 0.0 6.5e-16 58.3 0.0 1.7 2 0 0 2 2 2 1 Glutamine synthetase, catalytic domain VIT1 PF01988.19 KXS19070.1 - 1.1e-54 185.5 6.2 1.4e-54 185.2 6.2 1.1 1 0 0 1 1 1 1 VIT family AlaDh_PNT_C PF01262.21 KXS19070.1 - 0.057 12.7 0.3 0.057 12.7 0.3 1.5 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Synaptobrevin PF00957.21 KXS19071.1 - 2.5e-25 88.1 4.0 2.8e-25 87.9 4.0 1.0 1 0 0 1 1 1 1 Synaptobrevin TrbL PF04610.14 KXS19071.1 - 0.012 15.4 0.1 0.014 15.2 0.1 1.1 1 0 0 1 1 1 0 TrbL/VirB6 plasmid conjugal transfer protein Fzo_mitofusin PF04799.13 KXS19071.1 - 0.02 14.5 0.3 0.029 13.9 0.3 1.3 1 0 0 1 1 1 0 fzo-like conserved region Pex24p PF06398.11 KXS19071.1 - 0.025 13.6 0.0 0.025 13.6 0.0 1.1 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin DUF1676 PF07898.13 KXS19071.1 - 0.043 13.9 0.2 0.05 13.6 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) OppC_N PF12911.7 KXS19071.1 - 0.12 12.3 3.0 0.19 11.7 3.0 1.2 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C LRRC37AB_C PF14914.6 KXS19071.1 - 0.14 12.0 2.0 0.16 11.9 2.0 1.3 1 1 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain UPF0515 PF15135.6 KXS19071.1 - 0.27 10.5 0.3 0.3 10.4 0.3 1.0 1 0 0 1 1 1 0 Uncharacterised protein UPF0515 Glyoxalase PF00903.25 KXS19072.1 - 1.7e-06 28.2 0.0 2.2e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily TPR_8 PF13181.6 KXS19072.1 - 0.0051 16.9 1.2 0.81 10.1 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 KXS19072.1 - 0.0058 16.6 0.7 0.87 9.9 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat Glyoxalase_2 PF12681.7 KXS19072.1 - 0.24 11.4 0.0 0.33 10.9 0.0 1.2 1 0 0 1 1 1 0 Glyoxalase-like domain LysM PF01476.20 KXS19074.1 - 1.2e-05 25.2 0.0 4e-05 23.6 0.0 1.9 2 0 0 2 2 2 1 LysM domain DUF4407 PF14362.6 KXS19074.1 - 0.018 14.4 6.7 0.018 14.4 6.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Cut12 PF11500.8 KXS19074.1 - 0.054 13.4 4.6 0.083 12.8 4.6 1.3 1 0 0 1 1 1 0 Spindle pole body formation-associated protein DUF5320 PF17253.2 KXS19074.1 - 0.2 12.8 2.0 0.24 12.5 1.4 1.5 1 1 0 1 1 1 0 Family of unknown function (DUF5320) HemX PF04375.14 KXS19074.1 - 0.28 10.4 15.3 0.31 10.3 15.3 1.2 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase ATP-synt_E PF05680.12 KXS19074.1 - 0.28 11.5 7.5 0.54 10.6 7.5 1.5 1 0 0 1 1 1 0 ATP synthase E chain TFIIA PF03153.13 KXS19074.1 - 1.9 8.4 12.8 2 8.3 12.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit AP1AR PF15745.5 KXS19074.1 - 4 7.0 7.2 5.8 6.5 7.2 1.2 1 0 0 1 1 1 0 AP-1 complex-associated regulatory protein Med15 PF09606.10 KXS19074.1 - 7.1 5.2 20.6 7 5.2 20.6 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal LysM PF01476.20 KXS19075.1 - 4.7e-09 36.2 0.3 7.4e-09 35.5 0.3 1.3 1 0 0 1 1 1 1 LysM domain PepSY_TM PF03929.16 KXS19075.1 - 0.013 15.1 1.2 0.016 14.9 1.2 1.2 1 0 0 1 1 1 0 PepSY-associated TM region p450 PF00067.22 KXS19078.1 - 5.7e-26 91.3 0.0 1.2e-25 90.2 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 ERG4_ERG24 PF01222.17 KXS19079.1 - 1.4e-142 475.5 9.9 3.6e-142 474.1 9.9 1.6 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 KXS19079.1 - 0.0066 16.0 2.2 0.0066 16.0 2.2 2.3 3 1 0 3 3 3 1 Protein of unknown function (DUF1295) RRM_1 PF00076.22 KXS19081.1 - 5.1e-32 109.5 0.6 3.9e-19 68.2 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 KXS19081.1 - 0.0021 17.9 0.0 0.63 9.8 0.0 2.3 2 0 0 2 2 2 2 Rrp7 RRM-like N-terminal domain RRM_7 PF16367.5 KXS19081.1 - 0.019 15.1 0.1 0.69 10.1 0.0 2.8 2 1 0 2 2 2 0 RNA recognition motif XS PF03468.14 KXS19081.1 - 0.067 13.5 0.0 0.24 11.7 0.0 1.8 2 0 0 2 2 2 0 XS domain PHM7_cyt PF14703.6 KXS19081.1 - 0.13 12.5 0.1 9.1 6.5 0.0 3.0 2 1 1 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter Ribosomal_S7e PF01251.18 KXS19083.1 - 1e-81 273.1 3.5 1.1e-81 273.0 3.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e Glucokinase PF02685.16 KXS19083.1 - 0.021 13.8 0.0 0.027 13.5 0.0 1.1 1 0 0 1 1 1 0 Glucokinase ParcG PF10274.9 KXS19084.1 - 1.1e-80 270.0 0.0 1.3e-80 269.8 0.0 1.0 1 0 0 1 1 1 1 Parkin co-regulated protein DCB PF16213.5 KXS19084.1 - 0.0019 17.9 0.0 0.0028 17.4 0.0 1.2 1 0 0 1 1 1 1 Dimerisation and cyclophilin-binding domain of Mon2 RRM_1 PF00076.22 KXS19085.1 - 4.5e-20 71.2 0.0 1.4e-11 44.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KXS19085.1 - 1.3e-09 37.7 0.0 0.00021 20.9 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KXS19085.1 - 0.0017 18.2 0.0 0.62 10.0 0.0 2.3 2 0 0 2 2 2 2 Occluded RNA-recognition motif CCDC71L PF15374.6 KXS19085.1 - 0.059 12.6 0.1 0.078 12.2 0.1 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 71L CDC45 PF02724.14 KXS19085.1 - 3.3 5.9 6.0 4.2 5.5 6.0 1.1 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 KXS19085.1 - 7.8 5.7 8.3 10 5.3 8.3 1.1 1 0 0 1 1 1 0 NOA36 protein OppC_N PF12911.7 KXS19086.1 - 0.16 11.9 0.3 0.16 11.9 0.3 1.7 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C APC_u14 PF16635.5 KXS19088.1 - 0.38 11.3 0.2 0.38 11.3 0.2 1.9 2 0 0 2 2 2 0 Unstructured region on APC between SAMP and APC_crr SnoaL_2 PF12680.7 KXS19089.1 - 1.9e-12 47.7 0.8 7.3e-07 29.8 0.0 2.6 2 1 0 2 2 2 2 SnoaL-like domain SnoaL PF07366.12 KXS19089.1 - 3.2e-09 36.7 4.5 0.0029 17.4 0.4 4.2 3 1 0 3 3 3 3 SnoaL-like polyketide cyclase SnoaL PF07366.12 KXS19090.1 - 4.1e-05 23.4 0.2 0.019 14.8 0.1 2.4 2 0 0 2 2 2 2 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 KXS19090.1 - 0.0017 19.0 0.1 0.14 12.8 0.0 2.3 2 0 0 2 2 2 2 SnoaL-like domain Dynamitin PF04912.14 KXS19091.1 - 2.5e-59 201.6 0.1 1.3e-58 199.3 0.1 1.8 1 1 0 1 1 1 1 Dynamitin FUSC PF04632.12 KXS19091.1 - 0.022 13.3 0.4 0.022 13.3 0.4 2.3 2 1 1 3 3 3 0 Fusaric acid resistance protein family DASH_Hsk3 PF08227.11 KXS19091.1 - 0.043 14.2 4.0 7 7.1 0.3 4.2 4 0 0 4 4 4 0 DASH complex subunit Hsk3 like Spectrin PF00435.21 KXS19091.1 - 0.15 12.6 4.5 0.51 10.8 0.2 2.9 3 0 0 3 3 2 0 Spectrin repeat TMF_TATA_bd PF12325.8 KXS19091.1 - 0.17 12.1 1.9 0.61 10.3 0.1 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DivIC PF04977.15 KXS19091.1 - 0.18 11.6 0.8 0.66 9.8 0.0 2.3 2 0 0 2 2 2 0 Septum formation initiator Spc24 PF08286.11 KXS19091.1 - 0.3 11.4 1.8 5.3 7.3 0.1 2.6 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Matrilin_ccoil PF10393.9 KXS19091.1 - 0.4 10.6 1.0 17 5.4 0.0 3.6 3 1 1 4 4 4 0 Trimeric coiled-coil oligomerisation domain of matrilin Snapin_Pallidin PF14712.6 KXS19091.1 - 0.4 11.1 2.4 2.1 8.8 0.2 3.3 4 1 0 4 4 4 0 Snapin/Pallidin ADIP PF11559.8 KXS19091.1 - 0.45 10.6 1.7 0.92 9.6 0.2 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Rx_N PF18052.1 KXS19091.1 - 0.75 10.1 4.3 0.52 10.6 1.7 2.1 2 0 0 2 2 2 0 Rx N-terminal domain TBCA PF02970.16 KXS19091.1 - 0.79 10.1 3.9 0.45 10.9 0.3 2.4 3 0 0 3 3 2 0 Tubulin binding cofactor A Lebercilin PF15619.6 KXS19091.1 - 3.4 7.3 5.2 2.1 8.0 0.3 2.8 3 0 0 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease TMF_DNA_bd PF12329.8 KXS19091.1 - 8.6 6.4 6.2 39 4.3 0.2 3.2 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding SH3_9 PF14604.6 KXS19092.1 - 3.2e-09 36.5 0.2 3.2e-09 36.5 0.2 1.4 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 KXS19092.1 - 3.3e-08 33.0 0.2 5.4e-08 32.3 0.0 1.5 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 KXS19092.1 - 0.0023 17.6 0.0 0.0033 17.1 0.0 1.2 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.11 KXS19092.1 - 0.13 12.6 1.1 0.19 12.1 0.1 1.8 2 0 0 2 2 2 0 Bacterial SH3 domain AA_permease_2 PF13520.6 KXS19094.1 - 1.5e-50 172.3 47.6 1.8e-50 172.0 47.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXS19094.1 - 3.1e-20 72.2 43.5 4.2e-20 71.8 43.5 1.1 1 0 0 1 1 1 1 Amino acid permease Ribosomal_S11 PF00411.19 KXS19095.1 - 1.6e-20 73.5 0.1 2.6e-20 72.9 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S11 Sel1 PF08238.12 KXS19096.1 - 3.1e-25 88.1 15.8 9.9e-06 26.1 1.9 7.1 7 0 0 7 7 7 5 Sel1 repeat FA_hydroxylase PF04116.13 KXS19097.1 - 3e-21 76.2 13.1 3e-21 76.2 13.1 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily zf-C2H2 PF00096.26 KXS19098.1 - 1.4e-09 37.8 9.7 0.00012 22.3 0.8 3.1 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXS19098.1 - 4.3e-07 30.2 6.6 0.012 16.4 0.9 2.8 3 0 0 3 3 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KXS19098.1 - 5e-07 29.9 11.7 4.8e-05 23.6 1.0 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_3rep PF18868.1 KXS19098.1 - 0.00093 19.9 1.8 0.39 11.4 0.4 2.2 1 1 1 2 2 2 2 Zinc finger C2H2-type, 3 repeats RPN13_C PF16550.5 KXS19098.1 - 0.00098 19.3 0.7 0.0015 18.7 0.7 1.2 1 0 0 1 1 1 1 UCH-binding domain zf-C2H2_6 PF13912.6 KXS19098.1 - 0.0033 17.4 1.8 0.92 9.6 0.3 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-LYAR PF08790.11 KXS19098.1 - 0.005 16.7 1.2 0.017 15.0 0.2 2.1 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger DUF305 PF03713.13 KXS19098.1 - 0.0066 16.6 1.2 0.0092 16.1 1.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF305) ROS_MUCR PF05443.11 KXS19098.1 - 0.013 15.5 0.1 0.021 14.9 0.1 1.4 1 0 0 1 1 1 0 ROS/MUCR transcriptional regulator protein zf-C2H2_jaz PF12171.8 KXS19098.1 - 0.024 14.9 4.9 5.2 7.5 0.1 3.4 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KXS19098.1 - 0.025 15.0 6.8 1.7 9.1 0.5 2.9 4 0 0 4 4 3 0 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 KXS19098.1 - 0.041 14.2 1.4 0.071 13.4 1.3 1.6 1 1 0 1 1 1 0 C2H2-type zinc ribbon zf-C2H2_3 PF13878.6 KXS19098.1 - 0.075 12.9 3.8 0.53 10.1 0.6 2.5 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO XPA_N PF01286.18 KXS19098.1 - 0.18 11.9 1.3 1.7 8.7 0.1 2.2 2 0 0 2 2 2 0 XPA protein N-terminal zf-C2H2_2 PF12756.7 KXS19098.1 - 0.22 11.9 3.6 2.4 8.6 1.9 2.8 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) C1_2 PF03107.16 KXS19098.1 - 0.56 10.6 4.1 1.1 9.6 0.5 2.2 1 1 1 2 2 2 0 C1 domain SHS2_Rpb7-N PF03876.17 KXS19099.1 - 5.5e-09 36.3 0.3 1.5e-08 34.9 0.0 1.8 2 0 0 2 2 2 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 RPA43_OB PF17875.1 KXS19099.1 - 4.3e-08 33.8 0.0 4.3e-08 33.8 0.0 4.0 3 2 1 4 4 4 1 RPA43 OB domain in RNA Pol I RNA_pol_Rbc25 PF08292.12 KXS19099.1 - 0.016 15.4 0.0 0.016 15.4 0.0 3.4 3 2 0 3 3 3 0 RNA polymerase III subunit Rpc25 PGK PF00162.19 KXS19100.1 - 2e-148 494.4 0.4 2.3e-148 494.2 0.4 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase G-patch PF01585.23 KXS19101.1 - 3.8e-12 45.9 3.0 3.8e-12 45.9 3.0 2.2 2 0 0 2 2 2 1 G-patch domain R3H PF01424.22 KXS19101.1 - 0.00073 19.5 0.0 0.0014 18.6 0.0 1.5 1 0 0 1 1 1 1 R3H domain G-patch_2 PF12656.7 KXS19101.1 - 0.00099 19.2 1.9 0.00099 19.2 1.9 2.0 2 0 0 2 2 2 1 G-patch domain Glyco_hydro_5_C PF18564.1 KXS19102.1 - 0.001 19.5 0.2 0.0021 18.5 0.2 1.6 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain Gp_dh_C PF02800.20 KXS19103.1 - 1.5e-66 222.8 0.0 2.6e-66 222.1 0.0 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 KXS19103.1 - 3.5e-39 133.2 0.0 6.6e-39 132.3 0.0 1.5 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 KXS19103.1 - 0.0075 16.4 0.2 0.026 14.6 0.0 2.0 3 0 0 3 3 3 1 Dihydrodipicolinate reductase, N-terminus Methyltransf_25 PF13649.6 KXS19104.1 - 6.5e-10 39.6 0.1 1.2e-09 38.7 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXS19104.1 - 1.9e-09 37.5 0.1 2.8e-09 36.9 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KXS19104.1 - 2.1e-09 37.2 0.2 2.8e-09 36.8 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 KXS19104.1 - 3.4e-07 30.8 0.0 7.7e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 KXS19104.1 - 5.3e-06 25.6 0.1 7.4e-06 25.1 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_23 PF13489.6 KXS19104.1 - 8.6e-06 25.7 0.0 1.4e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXS19104.1 - 0.00033 20.2 0.1 0.00053 19.6 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 KXS19104.1 - 0.0014 19.3 0.0 0.0028 18.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KXS19104.1 - 0.0028 17.0 0.1 0.0039 16.5 0.1 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.7 KXS19104.1 - 0.0047 16.9 0.2 0.0077 16.2 0.2 1.3 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 KXS19104.1 - 0.011 15.8 0.0 0.019 15.1 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase PCMT PF01135.19 KXS19104.1 - 0.031 14.0 0.1 0.054 13.2 0.1 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.9 KXS19104.1 - 0.068 12.9 0.2 0.1 12.3 0.2 1.2 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_32 PF13679.6 KXS19104.1 - 0.11 12.5 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain DUF1194 PF06707.11 KXS19104.1 - 0.12 11.6 0.1 0.18 11.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1194) DUF287 PF03384.14 KXS19104.1 - 0.37 11.2 1.8 1.4 9.3 0.1 2.6 3 0 0 3 3 3 0 Drosophila protein of unknown function, DUF287 CBM_1 PF00734.18 KXS19105.1 - 5.1e-16 58.3 36.2 3.9e-10 39.5 11.3 3.2 3 1 0 3 3 3 2 Fungal cellulose binding domain Hormone_5 PF00184.17 KXS19105.1 - 1.3 9.8 17.3 2.8 8.8 17.3 1.6 1 1 0 1 1 1 0 Neurohypophysial hormones, C-terminal Domain Ribosomal_S3_C PF00189.20 KXS19106.1 - 1.2e-22 80.2 0.4 4.3e-22 78.4 0.3 1.9 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 KXS19106.1 - 4.7e-11 42.4 0.1 8.3e-11 41.6 0.1 1.4 1 0 0 1 1 1 1 KH domain Band_7 PF01145.25 KXS19107.1 - 0.098 12.7 0.0 0.23 11.5 0.0 1.6 1 1 0 1 1 1 0 SPFH domain / Band 7 family adh_short_C2 PF13561.6 KXS19108.1 - 3.4e-51 174.1 1.0 4.6e-51 173.6 1.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXS19108.1 - 1.8e-41 141.7 0.1 2.5e-41 141.3 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXS19108.1 - 1.6e-07 31.4 0.1 2.3e-07 30.9 0.1 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KXS19108.1 - 0.036 13.9 0.2 0.053 13.4 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain peroxidase PF00141.23 KXS19109.1 - 2.9e-23 82.8 0.0 4.7e-23 82.1 0.0 1.3 1 1 0 1 1 1 1 Peroxidase NAD_binding_1 PF00175.21 KXS19110.1 - 0.0063 17.1 0.0 0.91 10.2 0.0 2.8 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain TEP1_N PF05386.11 KXS19110.1 - 0.1 12.2 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 TEP1 N-terminal domain NO_synthase PF02898.15 KXS19111.1 - 7.3e-42 143.7 0.0 9.6e-42 143.3 0.0 1.2 1 0 0 1 1 1 1 Nitric oxide synthase, oxygenase domain Flavodoxin_1 PF00258.25 KXS19111.1 - 1.5e-24 86.8 0.0 2.5e-24 86.1 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin FAD_binding_1 PF00667.20 KXS19111.1 - 3.6e-17 62.7 0.0 1.1e-08 34.9 0.0 2.2 1 1 1 2 2 2 2 FAD binding domain NAD_binding_1 PF00175.21 KXS19111.1 - 3.9e-10 40.3 0.0 1.1e-09 38.9 0.0 1.8 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain bZIP_1 PF00170.21 KXS19112.1 - 7.2e-08 32.4 9.8 1.3e-07 31.6 9.8 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KXS19112.1 - 4e-06 26.8 10.5 8.3e-06 25.8 10.5 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KXS19112.1 - 0.0014 19.1 4.0 0.0027 18.2 4.0 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor P53_tetramer PF07710.11 KXS19112.1 - 0.048 13.0 0.1 0.09 12.1 0.1 1.4 1 0 0 1 1 1 0 P53 tetramerisation motif DUF4094 PF13334.6 KXS19112.1 - 0.061 13.7 1.0 0.12 12.8 1.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) Pet191_N PF10203.9 KXS19113.1 - 0.089 13.1 1.4 0.27 11.6 1.4 1.8 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 TauD PF02668.16 KXS19114.1 - 2.8e-38 132.3 0.1 5.4e-38 131.3 0.1 1.4 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family PLDc_2 PF13091.6 KXS19116.1 - 3.4e-16 59.3 0.2 4.1e-08 33.2 0.2 4.1 2 2 0 2 2 2 2 PLD-like domain PLDc PF00614.22 KXS19116.1 - 1.1e-11 44.4 0.1 0.00012 22.0 0.0 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif DnaJ_C PF01556.18 KXS19117.1 - 1.6e-36 125.6 0.0 2.2e-36 125.2 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KXS19117.1 - 1.7e-25 88.9 3.5 3.1e-25 88.1 3.5 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KXS19117.1 - 5e-11 42.8 17.4 9.1e-11 42.0 17.4 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 KXS19117.1 - 3.2 7.8 17.7 0.16 11.9 3.4 3.0 1 1 2 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein Pkinase PF00069.25 KXS19120.1 - 2.2e-20 73.1 0.0 2.5e-14 53.3 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXS19120.1 - 3.6e-06 26.5 0.0 0.00016 21.1 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXS19120.1 - 9.7e-05 21.3 0.0 0.00018 20.4 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase DUF3915 PF13054.6 KXS19120.1 - 1.3 9.0 2.9 3 7.8 2.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) TAF4 PF05236.14 KXS19120.1 - 1.4 8.6 6.9 0.19 11.4 0.9 2.2 2 0 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family Ribosomal_60s PF00428.19 KXS19121.1 - 9.7e-20 71.0 18.2 2e-19 69.9 18.2 1.5 1 1 0 1 1 1 1 60s Acidic ribosomal protein Cytomega_UL84 PF06284.11 KXS19121.1 - 0.28 9.6 1.8 0.31 9.4 1.8 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein F-box-like PF12937.7 KXS19122.1 - 0.00096 19.0 0.0 0.0013 18.6 0.0 1.2 1 0 0 1 1 1 1 F-box-like 4HBT_3 PF13622.6 KXS19124.1 - 1.1e-19 71.7 0.0 1.4e-19 71.3 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily FtsJ PF01728.19 KXS19125.1 - 2.5e-43 148.2 0.0 3.3e-43 147.8 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase zf-C2H2 PF00096.26 KXS19127.1 - 2e-14 53.1 15.6 0.00022 21.5 1.2 3.3 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KXS19127.1 - 5.8e-13 48.6 11.2 9.5e-06 25.8 0.4 4.1 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KXS19127.1 - 7.8e-11 41.9 12.0 0.0028 18.4 0.4 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KXS19127.1 - 0.00036 20.7 0.5 0.28 11.5 0.0 3.1 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.10 KXS19127.1 - 0.004 17.2 8.3 0.066 13.3 3.4 2.5 1 1 2 3 3 3 2 Zinc ribbon domain zf-met PF12874.7 KXS19127.1 - 0.0049 17.2 3.8 0.84 10.1 0.1 3.1 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 KXS19127.1 - 0.011 15.4 8.7 1.4 8.7 0.2 3.2 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 KXS19127.1 - 0.012 15.6 9.5 0.037 14.0 0.1 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2HC_2 PF13913.6 KXS19127.1 - 0.027 14.4 6.3 0.17 11.8 0.4 2.6 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf_UBZ PF18439.1 KXS19127.1 - 0.078 12.6 2.8 3.2 7.4 0.0 3.0 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-C2HE PF16278.5 KXS19127.1 - 0.23 11.9 7.4 2.9 8.4 0.3 3.2 1 1 2 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger C1_4 PF07975.12 KXS19127.1 - 0.4 11.0 3.7 0.34 11.2 1.1 2.1 1 1 1 2 2 2 0 TFIIH C1-like domain zinc_ribbon_15 PF17032.5 KXS19127.1 - 0.74 10.6 4.8 8.7 7.2 5.1 2.1 1 1 1 2 2 2 0 zinc-ribbon family zf_C2H2_ZHX PF18387.1 KXS19127.1 - 0.85 9.3 5.8 15 5.3 0.4 3.1 1 1 2 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain Zn_ribbon_SprT PF17283.2 KXS19127.1 - 2.1 8.3 9.7 0.33 10.9 3.5 2.3 2 0 0 2 2 2 0 SprT-like zinc ribbon domain DZR PF12773.7 KXS19127.1 - 7.2 6.7 8.1 90 3.2 0.6 2.4 1 1 1 2 2 2 0 Double zinc ribbon Amidohydro_2 PF04909.14 KXS19128.1 - 3.1e-30 106.0 0.1 4.4e-30 105.5 0.1 1.2 1 0 0 1 1 1 1 Amidohydrolase Ank PF00023.30 KXS19129.1 - 3.1e-06 27.4 1.8 0.00097 19.5 0.1 3.7 4 0 0 4 4 4 1 Ankyrin repeat ZapB PF06005.12 KXS19129.1 - 2.1e-05 24.9 9.6 3.7e-05 24.1 9.6 1.4 1 0 0 1 1 1 1 Cell division protein ZapB Rootletin PF15035.6 KXS19129.1 - 0.00012 22.1 2.5 0.00016 21.8 2.5 1.2 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion ATG16 PF08614.11 KXS19129.1 - 0.0019 18.5 4.1 0.0027 18.0 4.1 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) XRCC4 PF06632.12 KXS19129.1 - 0.004 16.1 1.0 0.0057 15.6 1.0 1.1 1 0 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 IFT20 PF14931.6 KXS19129.1 - 0.0058 16.8 3.3 0.01 16.0 3.3 1.4 1 0 0 1 1 1 1 Intraflagellar transport complex B, subunit 20 HAP1_N PF04849.13 KXS19129.1 - 0.0097 15.1 3.0 0.015 14.6 3.0 1.2 1 0 0 1 1 1 1 HAP1 N-terminal conserved region Herpes_UL6 PF01763.16 KXS19129.1 - 0.013 14.1 0.4 0.017 13.7 0.4 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like TMF_DNA_bd PF12329.8 KXS19129.1 - 0.019 14.9 5.8 0.033 14.2 5.8 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding APG6_N PF17675.1 KXS19129.1 - 0.036 14.6 9.3 0.054 14.0 9.3 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region ADIP PF11559.8 KXS19129.1 - 0.036 14.2 3.7 0.056 13.5 3.7 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Atg14 PF10186.9 KXS19129.1 - 0.04 13.0 1.5 0.051 12.7 1.5 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Ank_4 PF13637.6 KXS19129.1 - 0.049 14.2 0.1 23 5.7 0.0 3.2 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXS19129.1 - 0.06 13.9 0.2 1.2 9.8 0.1 2.9 2 2 0 2 2 2 0 Ankyrin repeats (3 copies) YabA PF06156.13 KXS19129.1 - 0.081 13.6 2.3 0.13 12.9 2.3 1.3 1 0 0 1 1 1 0 Initiation control protein YabA Spc7 PF08317.11 KXS19129.1 - 0.1 11.4 5.6 0.14 11.0 5.6 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Ank_3 PF13606.6 KXS19129.1 - 0.12 13.0 0.2 16 6.5 0.0 3.1 3 0 0 3 3 3 0 Ankyrin repeat DUF4148 PF13663.6 KXS19129.1 - 0.22 11.7 3.4 8.8 6.6 0.6 3.2 3 0 0 3 3 2 0 Domain of unknown function (DUF4148) Cnn_1N PF07989.11 KXS19129.1 - 0.32 11.2 5.8 0.7 10.1 5.8 1.6 1 1 0 1 1 1 0 Centrosomin N-terminal motif 1 TPD52 PF04201.15 KXS19129.1 - 0.51 9.9 4.4 0.82 9.3 4.4 1.4 1 0 0 1 1 1 0 Tumour protein D52 family peroxidase PF00141.23 KXS19130.1 - 1.4e-46 159.0 0.0 2.2e-46 158.4 0.0 1.2 1 0 0 1 1 1 1 Peroxidase DUF4398 PF14346.6 KXS19130.1 - 0.29 11.8 0.1 0.29 11.8 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4398) DUF676 PF05057.14 KXS19131.1 - 4.2e-05 23.2 0.1 8.2e-05 22.2 0.1 1.5 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 KXS19131.1 - 0.00036 20.5 0.0 0.00048 20.1 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase PGAP1 PF07819.13 KXS19131.1 - 0.0034 17.1 0.0 0.0057 16.4 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_1 PF00561.20 KXS19131.1 - 0.028 14.0 0.3 3.7 7.1 0.0 2.6 2 0 0 2 2 2 0 alpha/beta hydrolase fold COesterase PF00135.28 KXS19132.1 - 5.1e-34 118.0 0.0 6.4e-34 117.7 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXS19132.1 - 0.017 15.0 0.0 0.031 14.1 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold GATA PF00320.27 KXS19133.1 - 1e-13 50.6 4.5 2e-13 49.7 4.5 1.5 1 0 0 1 1 1 1 GATA zinc finger ArfGap PF01412.18 KXS19133.1 - 0.003 17.6 0.2 0.0053 16.8 0.2 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf DZR PF12773.7 KXS19133.1 - 0.0072 16.3 1.9 0.024 14.7 1.9 1.8 1 1 0 1 1 1 1 Double zinc ribbon YhfH PF14149.6 KXS19133.1 - 0.094 12.7 1.2 2.5 8.1 0.3 2.3 2 0 0 2 2 2 0 YhfH-like protein Zn-ribbon_8 PF09723.10 KXS19133.1 - 0.18 11.9 2.1 0.29 11.3 1.1 1.9 2 1 0 2 2 2 0 Zinc ribbon domain DUF2256 PF10013.9 KXS19133.1 - 0.25 11.5 2.5 10 6.4 0.1 2.7 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) Nudix_N_2 PF14803.6 KXS19133.1 - 0.98 9.4 6.8 3.6 7.6 3.5 2.4 1 1 1 2 2 2 0 Nudix N-terminal Maf PF02545.14 KXS19134.1 - 2.4e-44 151.1 0.0 2.8e-44 150.9 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein NADH_Oxid_Nqo15 PF11497.8 KXS19134.1 - 0.061 13.4 0.5 0.29 11.2 0.0 2.2 2 1 1 3 3 3 0 NADH-quinone oxidoreductase chain 15 W2 PF02020.18 KXS19135.1 - 1.1e-14 54.3 0.4 1.1e-14 54.3 0.4 3.5 2 1 0 2 2 1 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.24 KXS19135.1 - 1.7e-09 37.0 12.2 0.0026 17.4 0.4 3.9 1 1 4 5 5 5 5 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.12 KXS19135.1 - 3.5e-05 22.9 0.2 0.029 13.3 0.0 2.2 1 1 1 2 2 2 2 L-fucokinase NTP_transferase PF00483.23 KXS19135.1 - 0.00046 19.8 0.0 0.00079 19.1 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 KXS19135.1 - 0.00054 20.4 0.1 0.0018 18.6 0.0 1.8 2 0 0 2 2 2 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 KXS19135.1 - 0.0012 18.6 1.3 0.0012 18.6 1.3 3.8 3 1 1 4 4 4 1 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 KXS19135.1 - 0.061 11.5 0.4 0.093 10.9 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) Cwf_Cwc_15 PF04889.12 KXS19135.1 - 0.26 11.0 29.9 0.15 11.8 2.0 3.0 3 0 0 3 3 3 0 Cwf15/Cwc15 cell cycle control protein RNase_H2_suC PF08615.11 KXS19135.1 - 1.6 8.9 8.0 13 5.9 0.9 2.9 2 1 0 2 2 2 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) FAM176 PF14851.6 KXS19135.1 - 2 8.1 26.8 0.64 9.7 0.0 3.4 3 0 0 3 3 3 0 FAM176 family RNA_pol_3_Rpc31 PF11705.8 KXS19135.1 - 2.9 8.1 39.3 0.086 13.1 20.4 3.9 4 0 0 4 4 4 0 DNA-directed RNA polymerase III subunit Rpc31 Kin17_mid PF10357.9 KXS19135.1 - 9 6.2 7.5 18 5.2 7.5 1.5 1 0 0 1 1 1 0 Domain of Kin17 curved DNA-binding protein TPP_enzyme_N PF02776.18 KXS19137.1 - 1.1e-21 77.2 0.1 1.2e-21 77.1 0.1 1.0 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KXS19138.1 - 8.1e-15 54.9 0.2 1.7e-14 53.8 0.2 1.6 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.6 KXS19138.1 - 0.1 11.8 0.1 0.15 11.3 0.1 1.2 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase A_deaminase PF00962.22 KXS19139.1 - 1.9e-61 208.2 0.0 2.3e-61 208.0 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase Amidohydro_1 PF01979.20 KXS19139.1 - 0.00042 19.7 0.3 0.0012 18.3 0.3 1.7 1 1 0 1 1 1 1 Amidohydrolase family RNA_pol_Rpb2_6 PF00562.28 KXS19140.1 - 1.3e-111 373.5 0.1 2.3e-111 372.6 0.1 1.4 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_3 PF04565.16 KXS19140.1 - 1.3e-28 99.0 0.0 2.5e-28 98.0 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_1 PF04563.15 KXS19140.1 - 7e-28 97.5 0.0 1.5e-27 96.5 0.0 1.5 1 1 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 KXS19140.1 - 2.1e-22 79.3 0.0 4.4e-22 78.3 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpa2_4 PF06883.12 KXS19140.1 - 1.2e-17 63.7 0.0 2.2e-17 62.8 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_2 PF04561.14 KXS19140.1 - 6.5e-12 45.5 0.0 1.3e-11 44.5 0.0 1.5 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 2 Rpr2 PF04032.16 KXS19140.1 - 0.29 11.5 1.1 0.68 10.3 1.1 1.6 1 0 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain GATA PF00320.27 KXS19141.1 - 8.2e-14 50.9 7.0 1.2e-13 50.4 7.0 1.3 1 0 0 1 1 1 1 GATA zinc finger ArfGap PF01412.18 KXS19141.1 - 5.7e-05 23.2 0.2 7.9e-05 22.7 0.2 1.2 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf DZR PF12773.7 KXS19141.1 - 0.023 14.7 1.9 0.15 12.1 2.0 1.8 1 1 1 2 2 2 0 Double zinc ribbon C1_2 PF03107.16 KXS19141.1 - 0.04 14.2 0.6 4.5 7.7 0.1 2.2 2 0 0 2 2 2 0 C1 domain Zn-ribbon_8 PF09723.10 KXS19141.1 - 0.097 12.8 1.1 0.23 11.6 0.9 1.7 1 1 1 2 2 2 0 Zinc ribbon domain SWIRM PF04433.17 KXS19142.1 - 1.8e-15 57.0 0.0 7e-15 55.1 0.0 2.0 1 1 0 1 1 1 1 SWIRM domain Prok-JAB PF14464.6 KXS19142.1 - 1.8e-10 40.6 0.2 4.6e-10 39.3 0.2 1.6 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain JAB PF01398.21 KXS19142.1 - 4.7e-08 33.0 0.0 1.1e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease AMP-binding PF00501.28 KXS19143.1 - 1.9e-22 79.4 0.5 1.1e-21 76.9 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXS19143.1 - 0.013 16.5 0.0 0.032 15.2 0.0 1.7 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain DUF3318 PF11780.8 KXS19143.1 - 0.048 13.6 1.7 3.7 7.5 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3318) TMEM238 PF15125.6 KXS19143.1 - 0.16 12.2 1.7 8.2 6.7 0.1 3.2 3 0 0 3 3 3 0 TMEM238 protein family adh_short PF00106.25 KXS19144.1 - 1.6e-45 155.0 0.2 2e-45 154.6 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXS19144.1 - 6.8e-36 124.0 0.2 8.2e-36 123.7 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXS19144.1 - 9.7e-10 38.6 0.2 1.6e-09 37.9 0.2 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KXS19144.1 - 0.013 15.4 0.2 0.019 14.9 0.2 1.2 1 0 0 1 1 1 0 NAD(P)H-binding DUF1776 PF08643.10 KXS19144.1 - 0.018 14.4 0.0 0.029 13.7 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 KXS19144.1 - 0.046 13.2 0.1 0.22 10.9 0.1 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family AF-4 PF05110.13 KXS19145.1 - 0.86 7.6 41.6 1.1 7.2 41.6 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Hamartin PF04388.12 KXS19145.1 - 1.3 7.6 26.6 1.6 7.3 26.6 1.1 1 0 0 1 1 1 0 Hamartin protein DUF966 PF06136.13 KXS19145.1 - 7.1 6.2 30.7 11 5.6 30.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Dynein_light PF01221.18 KXS19148.1 - 1.3e-22 79.9 0.1 1.5e-22 79.7 0.1 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Macro_2 PF14519.6 KXS19148.1 - 0.077 12.3 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Macro-like domain FumaraseC_C PF10415.9 KXS19148.1 - 0.1 13.0 0.4 0.15 12.5 0.4 1.4 1 1 0 1 1 1 0 Fumarase C C-terminus Pkinase PF00069.25 KXS19149.1 - 2.9e-51 174.4 0.1 7.8e-51 173.0 0.1 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS19149.1 - 1.7e-22 80.0 0.0 2.6e-22 79.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXS19149.1 - 0.011 15.6 0.1 0.021 14.7 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 KXS19149.1 - 0.034 13.7 0.2 0.072 12.7 0.2 1.5 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 KXS19149.1 - 0.044 13.1 0.0 0.18 11.1 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KXS19149.1 - 0.25 10.9 1.0 0.6 9.7 0.3 1.9 2 0 0 2 2 2 0 Choline/ethanolamine kinase SNF2_N PF00176.23 KXS19150.1 - 1.8e-64 217.7 0.1 2.9e-64 217.0 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.24 KXS19150.1 - 1.6e-23 82.4 5.4 4.1e-13 49.0 0.1 3.0 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.31 KXS19150.1 - 3.8e-20 72.3 0.0 8.2e-20 71.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXS19150.1 - 9.3e-09 35.5 0.0 4.7e-08 33.2 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Cdh1_DBD_1 PF18196.1 KXS19150.1 - 8.2e-07 29.4 0.0 8.2e-07 29.4 0.0 3.9 4 0 0 4 4 4 1 Chromodomain helicase DNA-binding domain 1 DUF4208 PF13907.6 KXS19150.1 - 2.1e-06 28.1 0.5 1.5e-05 25.3 0.0 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4208) ERCC3_RAD25_C PF16203.5 KXS19150.1 - 0.00024 20.4 0.1 0.00048 19.4 0.1 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase SLIDE PF09111.10 KXS19150.1 - 0.0073 16.3 0.0 0.035 14.1 0.0 2.2 1 0 0 1 1 1 1 SLIDE CDH1_2_SANT_HL1 PF18375.1 KXS19150.1 - 0.023 15.4 0.0 0.023 15.4 0.0 3.4 4 0 0 4 4 4 0 CDH1/2 SANT-Helical linker 1 CHDCT2 PF08074.11 KXS19150.1 - 0.04 14.1 2.6 0.069 13.3 0.0 2.8 3 0 0 3 3 3 0 CHDCT2 (NUC038) domain PCI PF01399.27 KXS19151.1 - 1.6e-11 44.6 0.1 4.6e-11 43.1 0.0 1.8 2 0 0 2 2 2 1 PCI domain eIF3m_C_helix PF18005.1 KXS19151.1 - 0.00012 21.7 1.2 0.00022 20.9 1.2 1.5 1 0 0 1 1 1 1 eIF3 subunit M, C-terminal helix Tospo_nucleocap PF01533.16 KXS19151.1 - 0.086 12.3 0.1 0.38 10.2 0.0 2.1 2 1 1 3 3 3 0 Tospovirus nucleocapsid protein Radial_spoke_3 PF06098.11 KXS19152.1 - 5.4e-112 373.7 8.9 7.1e-112 373.3 8.9 1.1 1 0 0 1 1 1 1 Radial spoke protein 3 AAA_32 PF13654.6 KXS19152.1 - 0.028 13.2 2.7 0.04 12.7 2.7 1.1 1 0 0 1 1 1 0 AAA domain Ntox1 PF15500.6 KXS19152.1 - 0.76 10.2 4.0 4.3 7.7 2.6 2.6 2 0 0 2 2 2 0 Putative RNase-like toxin, toxin_1 DUF4192 PF13830.6 KXS19152.1 - 3.4 7.6 15.5 1.2 9.1 3.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4192) MFS_1 PF07690.16 KXS19153.1 - 2.2e-25 89.3 80.0 9.9e-22 77.3 46.8 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily TIP49 PF06068.13 KXS19154.1 - 2.1e-168 560.0 0.9 2.7e-168 559.7 0.9 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 KXS19154.1 - 2e-22 79.1 0.0 6.6e-22 77.4 0.0 2.0 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 KXS19154.1 - 1.5e-11 44.8 0.2 1.7e-07 31.8 0.1 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KXS19154.1 - 5.6e-09 35.9 0.1 5.3e-06 26.3 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KXS19154.1 - 2.3e-05 24.7 0.0 0.14 12.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KXS19154.1 - 2.4e-05 24.8 0.1 0.00039 20.8 0.1 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.6 KXS19154.1 - 5.3e-05 23.6 1.2 0.00066 20.0 1.2 2.4 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KXS19154.1 - 0.00044 20.3 0.1 0.024 14.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 KXS19154.1 - 0.0005 20.3 0.0 0.0013 19.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 KXS19154.1 - 0.00059 19.5 0.0 0.0011 18.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 KXS19154.1 - 0.0011 18.7 0.1 0.52 10.0 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain DnaB_C PF03796.15 KXS19154.1 - 0.0012 18.2 0.0 0.0022 17.3 0.0 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_18 PF13238.6 KXS19154.1 - 0.0013 19.3 0.1 0.0089 16.6 0.0 2.4 3 0 0 3 3 2 1 AAA domain Zeta_toxin PF06414.12 KXS19154.1 - 0.0037 16.6 0.4 0.0098 15.2 0.2 1.7 2 0 0 2 2 2 1 Zeta toxin ResIII PF04851.15 KXS19154.1 - 0.0055 16.7 0.1 0.13 12.2 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF2075 PF09848.9 KXS19154.1 - 0.012 14.8 0.0 0.019 14.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Mg_chelatase PF01078.21 KXS19154.1 - 0.014 14.8 0.1 0.44 9.9 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 KXS19154.1 - 0.024 14.2 0.0 0.15 11.6 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_14 PF13173.6 KXS19154.1 - 0.029 14.4 0.0 6 6.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 KXS19154.1 - 0.03 14.1 0.1 0.062 13.0 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Parvo_NS1 PF01057.17 KXS19154.1 - 0.03 13.4 0.0 0.063 12.4 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ATPase PF06745.13 KXS19154.1 - 0.034 13.5 0.1 0.21 10.9 0.0 2.2 2 0 0 2 2 2 0 KaiC AAA_33 PF13671.6 KXS19154.1 - 0.04 14.1 0.0 0.23 11.6 0.0 2.2 3 0 0 3 3 2 0 AAA domain AAA_30 PF13604.6 KXS19154.1 - 0.049 13.3 0.1 1.4 8.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 KXS19154.1 - 0.086 12.8 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 KXS19154.1 - 0.095 12.6 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 NACHT domain zf-TFIIB PF13453.6 KXS19154.1 - 0.11 11.8 0.0 0.23 10.8 0.0 1.5 1 0 0 1 1 1 0 Transcription factor zinc-finger AAA_lid_2 PF17863.1 KXS19154.1 - 0.12 12.3 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA lid domain RNase_HII PF01351.18 KXS19155.1 - 2.7e-45 154.6 0.0 3.8e-45 154.2 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease HII Spc7 PF08317.11 KXS19156.1 - 0.019 13.9 20.1 0.059 12.2 10.0 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein BLOC1_2 PF10046.9 KXS19156.1 - 0.022 15.1 1.4 0.022 15.1 1.4 3.4 3 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4200 PF13863.6 KXS19156.1 - 0.12 12.8 23.5 0.51 10.7 8.5 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4200) DUF2452 PF10504.9 KXS19156.1 - 0.17 11.3 3.5 0.11 12.0 0.5 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2452) YabA PF06156.13 KXS19156.1 - 0.31 11.7 15.7 0.097 13.3 3.5 3.1 2 2 0 2 2 2 0 Initiation control protein YabA Herpes_UL36 PF03586.13 KXS19156.1 - 0.33 10.3 4.1 5.5 6.2 0.1 2.4 2 0 0 2 2 2 0 Herpesvirus UL36 tegument protein LXG PF04740.12 KXS19156.1 - 0.37 10.5 7.6 0.85 9.3 0.5 3.0 2 1 1 3 3 3 0 LXG domain of WXG superfamily DUF4407 PF14362.6 KXS19156.1 - 0.94 8.8 14.0 1.1 8.6 3.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Occludin_ELL PF07303.13 KXS19156.1 - 2.2 9.1 9.9 0.38 11.5 0.4 2.9 2 1 0 2 2 2 0 Occludin homology domain TPR_MLP1_2 PF07926.12 KXS19156.1 - 2.3 8.3 25.0 13 5.9 10.4 3.6 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein Di19_C PF14571.6 KXS19156.1 - 3.5 8.2 8.8 0.16 12.5 2.7 2.0 2 0 0 2 2 2 0 Stress-induced protein Di19, C-terminal Lebercilin PF15619.6 KXS19156.1 - 3.8 7.1 27.8 0.35 10.5 7.2 3.3 2 1 1 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease ZapB PF06005.12 KXS19156.1 - 5.5 7.5 25.2 0.73 10.3 2.0 4.2 3 1 0 4 4 4 0 Cell division protein ZapB DUF3552 PF12072.8 KXS19156.1 - 9.9 5.5 28.4 1.8 7.9 11.8 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3552) zf-DBF PF07535.12 KXS19157.1 - 4.7e-10 39.4 0.1 8.5e-10 38.6 0.1 1.5 1 0 0 1 1 1 1 DBF zinc finger Dfp1_Him1_M PF08630.10 KXS19157.1 - 6e-06 26.5 0.0 1.4e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 Dfp1/Him1, central region G10 PF01125.17 KXS19158.1 - 2.9e-68 228.2 5.3 3.2e-68 228.1 5.3 1.0 1 0 0 1 1 1 1 G10 protein SH3_9 PF14604.6 KXS19160.1 - 0.0012 18.7 0.1 0.0023 17.8 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXS19160.1 - 0.0033 17.0 0.0 0.0053 16.3 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KXS19160.1 - 0.089 12.5 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain Tetradecapep PF08187.11 KXS19160.1 - 0.85 9.8 4.6 19 5.6 0.0 3.4 3 0 0 3 3 3 0 Myoactive tetradecapeptides family Exo_endo_phos PF03372.23 KXS19161.1 - 1.8e-19 70.2 0.0 9.5e-19 67.8 0.0 2.2 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SAP18 PF06487.12 KXS19162.1 - 7.1e-21 74.9 0.0 1.1e-20 74.2 0.0 1.3 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) VWA_2 PF13519.6 KXS19164.1 - 0.00028 21.5 0.0 0.00086 19.9 0.0 1.7 2 0 0 2 2 2 1 von Willebrand factor type A domain Alpha_kinase PF02816.18 KXS19165.1 - 4.2e-28 98.7 0.0 5.9e-28 98.2 0.0 1.2 1 0 0 1 1 1 1 Alpha-kinase family GAS PF13851.6 KXS19165.1 - 0.51 9.7 5.9 0.33 10.3 2.4 2.0 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Flavi_M PF01004.19 KXS19166.1 - 0.045 13.5 0.0 0.098 12.4 0.0 1.5 1 0 0 1 1 1 0 Flavivirus envelope glycoprotein M V_ATPase_I_N PF18670.1 KXS19167.1 - 0.0027 18.0 1.1 0.013 15.9 1.4 2.1 2 0 0 2 2 2 1 V-type ATPase subunit I, N-terminal domain CP12 PF02672.15 KXS19167.1 - 0.056 14.2 1.7 0.056 14.2 1.7 2.7 2 1 0 2 2 2 0 CP12 domain Lectin_N PF03954.14 KXS19167.1 - 1.6 8.5 4.5 1.6 8.5 0.7 2.5 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain USP8_interact PF08941.10 KXS19167.1 - 5.7 6.7 6.7 0.56 10.0 0.2 2.2 2 1 1 3 3 3 0 USP8 interacting Cyt-b5 PF00173.28 KXS19168.1 - 2.2e-19 69.4 0.1 2.5e-19 69.2 0.1 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Chal_sti_synt_C PF02797.15 KXS19168.1 - 0.052 13.5 0.0 0.063 13.3 0.0 1.1 1 0 0 1 1 1 0 Chalcone and stilbene synthases, C-terminal domain Oxidored_molyb PF00174.19 KXS19169.1 - 1.1e-16 61.0 0.1 1.6e-16 60.4 0.1 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Ribosomal_60s PF00428.19 KXS19171.1 - 0.044 14.4 6.0 0.044 14.4 6.0 3.3 2 1 0 2 2 2 0 60s Acidic ribosomal protein F-box-like PF12937.7 KXS19173.1 - 0.00015 21.6 0.0 0.00028 20.7 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXS19173.1 - 0.012 15.5 0.0 0.024 14.5 0.0 1.4 1 0 0 1 1 1 0 F-box domain Sel1 PF08238.12 KXS19174.1 - 4.4e-26 90.7 12.1 3.6e-11 43.4 0.4 3.9 4 0 0 4 4 4 3 Sel1 repeat TPR_6 PF13174.6 KXS19174.1 - 0.00053 20.4 0.5 0.87 10.4 0.1 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 KXS19174.1 - 0.0035 18.0 3.8 0.051 14.2 1.5 2.9 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 KXS19174.1 - 0.0094 15.6 3.9 0.62 9.8 0.2 3.9 3 2 0 3 3 3 1 TPR repeat TPR_1 PF00515.28 KXS19174.1 - 4.8 7.2 11.7 8.8 6.3 0.2 4.4 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF4715 PF15835.5 KXS19175.1 - 0.0034 17.5 0.8 0.0066 16.5 0.8 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4715) ABC_tran PF00005.27 KXS19176.1 - 7.8e-15 55.6 0.0 2.6e-14 53.9 0.0 1.8 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KXS19176.1 - 5e-10 39.7 0.1 0.00031 20.7 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KXS19176.1 - 0.00059 19.5 0.1 0.0013 18.4 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 KXS19176.1 - 0.0029 17.1 0.0 1 8.7 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KXS19176.1 - 0.0058 16.5 0.0 0.0079 16.1 0.0 1.2 1 0 0 1 1 1 1 RsgA GTPase AAA_23 PF13476.6 KXS19176.1 - 0.007 16.9 0.1 0.01 16.4 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KXS19176.1 - 0.011 16.1 0.3 0.017 15.5 0.3 1.5 1 1 0 1 1 1 0 AAA ATPase domain DUF3584 PF12128.8 KXS19176.1 - 0.027 12.0 0.3 0.038 11.5 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) MMR_HSR1 PF01926.23 KXS19176.1 - 0.028 14.5 0.2 0.053 13.6 0.2 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_33 PF13671.6 KXS19176.1 - 0.038 14.2 0.0 0.062 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 KXS19176.1 - 0.039 13.6 0.1 0.056 13.2 0.1 1.1 1 0 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 KXS19176.1 - 0.058 13.0 0.6 0.13 11.9 0.4 1.6 1 1 0 1 1 1 0 AAA domain AAA_27 PF13514.6 KXS19176.1 - 0.069 12.7 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KXS19176.1 - 0.091 13.0 0.1 0.16 12.2 0.1 1.4 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KXS19176.1 - 0.11 11.8 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin FtsK_SpoIIIE PF01580.18 KXS19176.1 - 0.12 11.7 0.0 0.25 10.7 0.0 1.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_22 PF13401.6 KXS19176.1 - 0.14 12.5 0.1 0.35 11.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KXS19176.1 - 0.15 12.5 0.0 0.65 10.4 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 KXS19176.1 - 0.16 11.1 0.1 0.25 10.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ABC_membrane PF00664.23 KXS19178.1 - 1.2e-101 339.9 26.7 2.2e-54 185.0 5.3 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KXS19178.1 - 5.2e-66 221.3 0.0 3e-34 118.5 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KXS19178.1 - 3e-17 62.8 1.8 5.4e-06 26.0 0.1 4.2 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KXS19178.1 - 5.2e-10 39.7 0.1 0.0038 17.5 0.0 3.6 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KXS19178.1 - 6.6e-08 33.1 7.9 0.00094 19.6 1.0 3.8 2 2 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 KXS19178.1 - 5.5e-07 29.7 0.3 0.31 10.8 0.0 4.9 4 1 1 5 5 5 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KXS19178.1 - 2.4e-06 27.2 0.5 0.024 14.4 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KXS19178.1 - 3.2e-06 27.1 0.0 0.028 14.3 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_30 PF13604.6 KXS19178.1 - 6.2e-06 26.1 1.8 0.052 13.3 0.2 3.6 3 1 0 3 3 3 2 AAA domain AAA PF00004.29 KXS19178.1 - 1.3e-05 25.6 1.9 0.098 13.1 0.2 4.2 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF87 PF01935.17 KXS19178.1 - 1.5e-05 25.2 0.3 0.012 15.8 0.0 2.5 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_23 PF13476.6 KXS19178.1 - 3e-05 24.6 0.1 0.17 12.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 KXS19178.1 - 4.6e-05 22.8 1.6 0.18 11.1 0.0 3.4 4 0 0 4 4 4 2 Zeta toxin ABC_ATPase PF09818.9 KXS19178.1 - 5.4e-05 22.2 2.9 0.18 10.5 0.1 3.1 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_5 PF07728.14 KXS19178.1 - 5.6e-05 23.2 0.0 0.028 14.4 0.0 3.1 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 KXS19178.1 - 7.7e-05 23.2 0.0 0.12 12.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 KXS19178.1 - 0.0002 21.4 0.0 3.1 7.9 0.0 4.1 4 1 0 4 4 4 1 AAA domain AAA_24 PF13479.6 KXS19178.1 - 0.00027 20.7 0.0 0.5 10.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 KXS19178.1 - 0.00045 20.3 0.0 1.2 9.2 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase Cytidylate_kin PF02224.18 KXS19178.1 - 0.00059 19.6 0.0 0.075 12.8 0.0 2.6 2 0 0 2 2 2 1 Cytidylate kinase AAA_15 PF13175.6 KXS19178.1 - 0.00075 19.3 0.0 0.43 10.2 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain PRK PF00485.18 KXS19178.1 - 0.0011 18.8 0.0 1.7 8.3 0.0 2.3 2 0 0 2 2 2 2 Phosphoribulokinase / Uridine kinase family Rad17 PF03215.15 KXS19178.1 - 0.0011 18.9 0.0 0.35 10.8 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_28 PF13521.6 KXS19178.1 - 0.0012 19.1 0.0 3.3 7.9 0.1 3.2 3 1 0 3 3 3 1 AAA domain NB-ARC PF00931.22 KXS19178.1 - 0.0015 17.8 0.0 0.52 9.5 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain IstB_IS21 PF01695.17 KXS19178.1 - 0.0017 18.1 1.4 1 9.1 0.0 4.0 4 0 0 4 4 4 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 KXS19178.1 - 0.0018 17.7 0.0 0.56 9.6 0.0 2.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI G-alpha PF00503.20 KXS19178.1 - 0.0025 17.0 0.0 0.24 10.5 0.0 2.2 2 0 0 2 2 2 1 G-protein alpha subunit AAA_7 PF12775.7 KXS19178.1 - 0.0029 17.1 0.0 0.18 11.3 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region Sigma54_activat PF00158.26 KXS19178.1 - 0.0046 16.7 0.0 0.11 12.2 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain RNA_helicase PF00910.22 KXS19178.1 - 0.0062 16.9 0.0 6.8 7.1 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_33 PF13671.6 KXS19178.1 - 0.0064 16.7 2.9 0.65 10.1 0.2 3.0 3 1 0 3 3 2 1 AAA domain NACHT PF05729.12 KXS19178.1 - 0.01 15.8 0.1 3.4 7.5 0.0 2.6 2 0 0 2 2 2 0 NACHT domain SbcCD_C PF13558.6 KXS19178.1 - 0.011 16.0 7.3 2.2 8.6 0.6 4.5 3 2 0 3 3 2 0 Putative exonuclease SbcCD, C subunit AAA_17 PF13207.6 KXS19178.1 - 0.017 15.5 0.0 12 6.3 0.0 2.8 3 0 0 3 3 2 0 AAA domain AAA_25 PF13481.6 KXS19178.1 - 0.024 14.2 0.6 2.6 7.6 0.0 3.0 3 0 0 3 3 3 0 AAA domain ATP-synt_ab PF00006.25 KXS19178.1 - 0.031 13.9 0.4 1.1 8.8 0.0 2.7 3 0 0 3 3 2 0 ATP synthase alpha/beta family, nucleotide-binding domain APS_kinase PF01583.20 KXS19178.1 - 0.035 14.0 0.0 0.22 11.4 0.0 2.2 2 0 0 2 2 2 0 Adenylylsulphate kinase TniB PF05621.11 KXS19178.1 - 0.074 12.5 0.0 26 4.1 0.0 3.2 3 0 0 3 3 3 0 Bacterial TniB protein Sigma54_activ_2 PF14532.6 KXS19178.1 - 0.13 12.4 0.0 0.53 10.4 0.0 2.0 2 0 0 2 2 1 0 Sigma-54 interaction domain PB1 PF00564.24 KXS19179.1 - 7.4e-09 35.4 0.0 1.6e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 PB1 domain AT_hook PF02178.19 KXS19180.1 - 0.011 15.6 0.4 0.011 15.6 0.4 6.7 6 0 0 6 6 6 0 AT hook motif PB1 PF00564.24 KXS19181.1 - 1.3e-08 34.7 0.0 2.2e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 PB1 domain PBD PF00786.28 KXS19182.1 - 6.8e-12 45.6 0.0 1.2e-11 44.7 0.0 1.4 1 0 0 1 1 1 1 P21-Rho-binding domain WH1 PF00568.23 KXS19182.1 - 4.3e-11 42.7 0.0 6.5e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 WH1 domain WH2 PF02205.20 KXS19182.1 - 1.5e-05 24.7 0.0 3e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 WH2 motif GP67 PF17634.2 KXS19182.1 - 0.045 14.2 2.2 0.081 13.3 2.2 1.4 1 0 0 1 1 1 0 Gene product 67 Prp18 PF02840.15 KXS19183.1 - 4.1e-58 195.5 0.3 4.1e-58 195.5 0.3 2.0 2 0 0 2 2 2 1 Prp18 domain PRP4 PF08799.11 KXS19183.1 - 1.3e-12 47.1 2.9 4.3e-12 45.4 2.9 2.0 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like CLASP_N PF12348.8 KXS19184.1 - 9.1e-17 61.4 1.3 1.2e-08 34.8 0.2 3.7 4 0 0 4 4 4 3 CLASP N terminal HEAT_2 PF13646.6 KXS19184.1 - 1.3e-06 28.7 22.2 1.3 9.4 0.0 8.4 4 3 2 8 8 8 4 HEAT repeats Urb2 PF10441.9 KXS19184.1 - 0.00077 19.5 1.2 0.0019 18.2 0.3 2.2 2 0 0 2 2 2 1 Urb2/Npa2 family Cnd1 PF12717.7 KXS19184.1 - 0.0097 16.0 0.9 3.1 7.8 0.0 4.2 4 1 1 5 5 5 1 non-SMC mitotic condensation complex subunit 1 Sec7_N PF12783.7 KXS19184.1 - 0.012 15.5 0.0 0.03 14.2 0.0 1.6 1 0 0 1 1 1 0 Guanine nucleotide exchange factor in Golgi transport N-terminal NUC173 PF08161.12 KXS19184.1 - 0.018 14.7 0.3 9.3 5.9 0.0 3.2 3 0 0 3 3 3 0 NUC173 domain EAP30 PF04157.16 KXS19185.1 - 3.8e-19 68.9 0.0 5.5e-19 68.4 0.0 1.2 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.8 KXS19185.1 - 0.00031 20.9 0.0 0.00054 20.1 0.0 1.3 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 Vps36-NZF-N PF16988.5 KXS19185.1 - 0.00055 19.3 1.5 0.00055 19.3 1.5 2.3 2 0 0 2 2 2 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain DZR PF12773.7 KXS19185.1 - 0.0013 18.7 8.1 0.024 14.7 1.3 2.2 1 1 2 3 3 3 3 Double zinc ribbon BBL5 PF07289.11 KXS19185.1 - 0.12 11.5 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 Bardet-Biedl syndrome 5 protein zf-Sec23_Sec24 PF04810.15 KXS19185.1 - 0.38 10.8 0.1 0.38 10.8 0.1 3.4 4 1 0 4 4 4 0 Sec23/Sec24 zinc finger zf-RanBP PF00641.18 KXS19185.1 - 0.45 9.9 14.1 0.019 14.3 2.8 2.8 2 1 0 2 2 2 0 Zn-finger in Ran binding protein and others UvrD-helicase PF00580.21 KXS19186.1 - 3e-56 191.2 0.0 5.4e-54 183.8 0.0 2.2 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 KXS19186.1 - 5.2e-37 128.0 0.0 1.5e-20 73.9 0.0 2.1 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 KXS19186.1 - 2.1e-32 112.5 0.0 4.2e-32 111.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KXS19186.1 - 9.1e-08 32.0 0.1 4.1e-06 26.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain UvrD_C_2 PF13538.6 KXS19186.1 - 2.1e-07 30.6 0.5 2.2e-06 27.4 0.5 2.5 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_11 PF13086.6 KXS19186.1 - 0.00044 20.1 0.0 0.00083 19.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 KXS19186.1 - 0.0044 16.8 0.2 14 5.3 0.0 3.3 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase WD40 PF00400.32 KXS19187.1 - 7.6e-33 112.0 20.9 2.2e-06 28.3 0.2 8.0 8 1 0 8 8 7 6 WD domain, G-beta repeat zf-C3HC4_2 PF13923.6 KXS19187.1 - 5.3e-13 48.6 12.6 6.9e-13 48.2 10.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXS19187.1 - 8.1e-09 35.4 10.2 9.6e-09 35.1 7.5 2.5 2 0 0 2 2 2 1 RING-type zinc-finger Sina PF03145.16 KXS19187.1 - 9.3e-09 35.5 0.1 1.6e-08 34.8 0.1 1.3 1 0 0 1 1 1 1 Seven in absentia protein family zf-RING_2 PF13639.6 KXS19187.1 - 1.3e-08 35.0 9.4 1.3e-08 35.0 9.4 2.2 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4 PF00097.25 KXS19187.1 - 5.2e-08 32.6 12.4 5.2e-08 32.6 10.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KXS19187.1 - 5.1e-07 29.9 5.2 1.6e-06 28.3 5.2 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain Nup160 PF11715.8 KXS19187.1 - 1.4e-06 27.3 2.8 0.039 12.6 0.2 3.3 2 1 1 3 3 3 2 Nucleoporin Nup120/160 zf-RING_6 PF14835.6 KXS19187.1 - 2e-06 27.6 4.7 9.5e-06 25.4 4.4 2.3 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-RING_5 PF14634.6 KXS19187.1 - 2.1e-06 27.6 11.6 2.1e-06 27.6 11.6 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KXS19187.1 - 2.2e-06 27.4 11.0 5.6e-06 26.1 11.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KXS19187.1 - 2.9e-06 27.3 10.0 2.9e-06 27.3 10.0 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 KXS19187.1 - 9e-06 25.7 6.4 1.9e-05 24.7 6.4 1.5 1 0 0 1 1 1 1 zinc RING finger of MSL2 U-box PF04564.15 KXS19187.1 - 1.3e-05 25.2 0.0 3.1e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 U-box domain Nucleoporin_N PF08801.11 KXS19187.1 - 1.9e-05 23.6 0.7 0.048 12.4 0.0 3.1 1 1 0 3 3 3 1 Nup133 N terminal like ANAPC4_WD40 PF12894.7 KXS19187.1 - 3.5e-05 24.0 0.1 1.9 8.8 0.1 3.9 2 2 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain zf-Nse PF11789.8 KXS19187.1 - 0.00011 22.0 7.2 0.00024 20.9 7.2 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit PQQ_3 PF13570.6 KXS19187.1 - 0.00032 21.1 0.1 0.89 10.1 0.4 4.2 4 0 0 4 4 3 1 PQQ-like domain zf-TRAF_2 PF15965.5 KXS19187.1 - 0.0041 17.5 1.3 0.0041 17.5 1.3 2.4 1 1 1 2 2 1 1 TRAF-like zinc-finger Prok-RING_4 PF14447.6 KXS19187.1 - 0.0086 15.9 13.1 0.12 12.3 13.3 2.6 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KXS19187.1 - 0.037 14.1 5.2 0.14 12.2 5.2 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger PQQ PF01011.21 KXS19187.1 - 0.07 13.1 0.3 0.88 9.6 0.0 2.8 3 0 0 3 3 3 0 PQQ enzyme repeat zf-C3H2C3 PF17122.5 KXS19187.1 - 2.5 8.2 11.3 1.1 9.4 8.6 1.9 2 0 0 2 2 1 0 Zinc-finger zf-RING_4 PF14570.6 KXS19187.1 - 7.2 6.5 15.0 0.25 11.2 8.2 2.1 2 1 0 2 2 1 0 RING/Ubox like zinc-binding domain zf-P11 PF03854.14 KXS19187.1 - 7.6 6.3 9.2 47 3.7 9.2 2.1 1 1 1 2 2 2 0 P-11 zinc finger Glyco_transf_15 PF01793.16 KXS19188.1 - 1e-66 225.5 0.3 1.3e-66 225.1 0.3 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase PALP PF00291.25 KXS19189.1 - 5.5e-59 200.0 1.7 6.2e-59 199.8 1.7 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF5129 PF17173.4 KXS19189.1 - 0.022 13.9 0.5 0.042 13.0 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5129) DUF2252 PF10009.9 KXS19190.1 - 3.9e-62 210.6 0.0 5e-62 210.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2252) APH PF01636.23 KXS19190.1 - 0.0064 16.4 1.0 0.012 15.6 1.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family FAP PF07174.11 KXS19190.1 - 1.1 8.7 8.2 1.6 8.1 8.2 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) E1_dh PF00676.20 KXS19192.1 - 1.4e-79 267.1 0.0 1.7e-79 266.9 0.0 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component Transketolase_N PF00456.21 KXS19192.1 - 0.0044 16.0 0.0 0.01 14.8 0.0 1.5 2 0 0 2 2 2 1 Transketolase, thiamine diphosphate binding domain CASP_C PF08172.12 KXS19193.1 - 1.9e-53 181.4 1.8 1.9e-53 181.4 1.8 2.9 2 2 0 2 2 2 1 CASP C terminal ZapB PF06005.12 KXS19193.1 - 0.025 15.0 0.2 0.025 15.0 0.2 5.8 6 2 1 7 7 7 0 Cell division protein ZapB DUF4349 PF14257.6 KXS19193.1 - 0.99 8.8 12.7 0.23 10.9 8.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) TSC22 PF01166.18 KXS19193.1 - 7.6 6.9 8.0 32 4.9 0.2 4.1 3 1 0 3 3 3 0 TSC-22/dip/bun family Med14 PF08638.11 KXS19194.1 - 9.6e-12 44.7 0.0 2.1e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 Mediator complex subunit MED14 Med14 PF08638.11 KXS19195.1 - 1.3e-21 76.9 0.1 1.5e-21 76.7 0.1 1.1 1 0 0 1 1 1 1 Mediator complex subunit MED14 RVT_thumb PF06817.14 KXS19195.1 - 0.029 14.2 0.2 0.6 10.0 0.0 2.2 1 1 1 2 2 2 0 Reverse transcriptase thumb domain Creatinase_N_2 PF16189.5 KXS19196.1 - 9.3e-47 159.1 0.0 2.4e-46 157.8 0.0 1.7 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 KXS19196.1 - 1.6e-46 158.6 0.0 2.3e-46 158.1 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.18 KXS19196.1 - 2.7e-23 83.1 0.1 1.5e-17 64.4 0.0 2.3 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain Peptidase_M24_C PF16188.5 KXS19196.1 - 1e-20 73.5 0.0 4.2e-20 71.6 0.0 2.1 2 0 0 2 2 2 1 C-terminal region of peptidase_M24 Biopterin_H PF00351.21 KXS19197.1 - 1.3e-160 533.9 0.0 1.9e-160 533.3 0.0 1.2 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase ACT PF01842.25 KXS19197.1 - 1.6e-06 27.8 0.0 3.2e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 ACT domain ACT_4 PF13291.6 KXS19197.1 - 0.0018 18.8 0.0 0.0036 17.9 0.0 1.5 1 0 0 1 1 1 1 ACT domain ubiquitin PF00240.23 KXS19198.1 - 5.9e-08 32.4 0.3 2.2e-07 30.5 0.3 1.7 1 1 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 KXS19198.1 - 2.4e-06 27.9 0.1 1.5e-05 25.3 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD PF11976.8 KXS19198.1 - 0.0021 17.9 0.2 0.0088 15.9 0.2 1.8 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like PI3K_rbd PF00794.18 KXS19198.1 - 0.059 13.5 0.0 0.067 13.4 0.0 1.2 1 0 0 1 1 1 0 PI3-kinase family, ras-binding domain DUF5343 PF17278.2 KXS19198.1 - 0.13 12.3 0.0 0.16 12.1 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5343) Cpn60_TCP1 PF00118.24 KXS19199.1 - 3.8e-150 500.8 7.4 4.4e-150 500.6 7.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family CRM1_repeat PF18777.1 KXS19199.1 - 0.16 11.5 0.0 0.33 10.5 0.0 1.5 1 0 0 1 1 1 0 Chromosome region maintenance or exportin repeat GPP34 PF05719.11 KXS19200.1 - 2.9e-56 190.7 0.5 3.4e-56 190.5 0.5 1.0 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) SNAP PF14938.6 KXS19201.1 - 9.2e-106 353.4 22.5 1.1e-105 353.2 22.5 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 KXS19201.1 - 4.6e-06 26.8 13.9 0.0073 16.6 0.9 3.7 1 1 3 4 4 4 4 Tetratricopeptide repeat DHR-2 PF06920.13 KXS19201.1 - 0.00012 20.9 0.6 0.00019 20.3 0.6 1.3 1 0 0 1 1 1 1 Dock homology region 2 Spatacsin_C PF14649.6 KXS19201.1 - 0.0041 16.3 8.7 0.29 10.2 3.6 2.3 1 1 1 2 2 2 2 Spatacsin C-terminus TPR_6 PF13174.6 KXS19201.1 - 0.016 15.8 16.3 5.3 7.9 0.2 5.9 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_19 PF14559.6 KXS19201.1 - 0.84 10.2 14.0 0.12 12.8 2.4 4.0 2 2 1 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 KXS19201.1 - 6.9 7.4 18.3 5.4 7.7 0.8 4.7 3 2 3 6 6 6 0 Tetratricopeptide repeat zf-HC5HC2H_2 PF13832.6 KXS19202.1 - 8.6e-34 116.0 7.2 8.6e-34 116.0 7.2 2.1 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 KXS19202.1 - 9.1e-26 89.9 4.8 9.1e-26 89.9 4.8 3.1 3 0 0 3 3 3 1 PHD-like zinc-binding domain Bromodomain PF00439.25 KXS19202.1 - 3.1e-19 68.8 0.0 6.9e-19 67.7 0.0 1.6 1 0 0 1 1 1 1 Bromodomain EPL1 PF10513.9 KXS19202.1 - 1.5e-17 64.5 11.5 1.5e-17 64.5 11.5 4.3 3 2 0 3 3 3 1 Enhancer of polycomb-like PHD_2 PF13831.6 KXS19202.1 - 1.2e-14 53.5 1.8 1.2e-14 53.5 1.8 2.4 2 0 0 2 2 2 1 PHD-finger PHD PF00628.29 KXS19202.1 - 4.6e-11 42.4 17.6 1.6e-10 40.7 4.6 2.8 2 0 0 2 2 2 2 PHD-finger zf-PHD-like PF15446.6 KXS19202.1 - 0.0046 16.6 0.9 0.0046 16.6 0.9 2.3 2 0 0 2 2 2 1 PHD/FYVE-zinc-finger like domain C1_1 PF00130.22 KXS19202.1 - 0.016 15.0 0.2 0.016 15.0 0.2 2.5 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Zf_RING PF16744.5 KXS19202.1 - 3.3 7.9 11.2 2.9 8.1 1.0 2.7 2 0 0 2 2 2 0 KIAA1045 RING finger Pkinase PF00069.25 KXS19203.1 - 1.3e-10 41.1 0.0 2e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain HEAT PF02985.22 KXS19203.1 - 3.1e-08 33.2 0.2 0.04 14.2 0.0 5.2 5 0 0 5 5 5 1 HEAT repeat Pkinase_Tyr PF07714.17 KXS19203.1 - 9e-07 28.4 0.0 1.4e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_2 PF13646.6 KXS19203.1 - 3.3e-05 24.2 0.1 0.0059 17.0 0.1 3.2 1 1 2 3 3 3 1 HEAT repeats Cnd1 PF12717.7 KXS19203.1 - 0.00032 20.8 0.3 0.094 12.8 0.1 2.9 1 1 1 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 KXS19203.1 - 0.01 16.3 1.6 0.11 13.1 0.3 3.2 2 1 1 3 3 3 0 HEAT-like repeat Vac14_Fab1_bd PF12755.7 KXS19203.1 - 0.035 14.7 0.1 21 5.8 0.0 3.7 3 1 1 4 4 4 0 Vacuolar 14 Fab1-binding region She9_MDM33 PF05546.11 KXS19204.1 - 1.3e-22 80.6 1.5 1.6e-22 80.3 1.5 1.1 1 0 0 1 1 1 1 She9 / Mdm33 family Tis11B_N PF04553.12 KXS19204.1 - 0.016 15.7 0.1 0.053 14.1 0.0 1.7 1 1 1 2 2 2 0 Tis11B like protein, N terminus Trans_reg_C PF00486.28 KXS19204.1 - 0.07 13.2 0.1 0.14 12.3 0.1 1.5 1 0 0 1 1 1 0 Transcriptional regulatory protein, C terminal NAP PF00956.18 KXS19205.1 - 1.2e-93 313.2 7.6 1.5e-93 312.9 7.6 1.1 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) Sp38 PF07354.12 KXS19205.1 - 0.056 12.9 0.1 0.39 10.1 0.0 1.9 2 0 0 2 2 2 0 Zona-pellucida-binding protein (Sp38) SAPS PF04499.15 KXS19205.1 - 0.27 10.0 4.1 0.38 9.5 4.1 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SDA1 PF05285.12 KXS19205.1 - 2.5 7.4 15.7 4.3 6.7 15.7 1.3 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 KXS19205.1 - 2.9 7.1 14.7 5.2 6.3 14.7 1.4 1 0 0 1 1 1 0 BUD22 NRDE-2 PF08424.10 KXS19206.1 - 2.6e-69 233.8 3.1 4.1e-69 233.2 0.5 2.3 3 0 0 3 3 3 1 NRDE-2, necessary for RNA interference TPR_14 PF13428.6 KXS19206.1 - 4.2e-08 33.3 4.3 0.03 15.1 0.0 6.1 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 KXS19206.1 - 0.00071 20.0 0.9 0.072 13.6 0.1 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 KXS19206.1 - 0.0071 16.4 0.7 0.38 11.0 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 KXS19206.1 - 0.013 15.9 0.3 0.061 13.7 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 KXS19206.1 - 0.015 15.5 0.1 1.9 8.9 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 KXS19206.1 - 0.038 14.6 2.3 14 6.6 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 KXS19206.1 - 0.14 12.4 0.1 0.54 10.6 0.1 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_16 PF13432.6 KXS19206.1 - 0.85 10.3 4.2 14 6.4 0.1 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat NADHdh_A3 PF14987.6 KXS19207.1 - 0.13 12.6 0.0 0.13 12.6 0.0 1.2 1 0 0 1 1 1 0 NADH dehydrogenase 1 alpha subcomplex subunit 3 GDC-P PF02347.16 KXS19208.1 - 3.8e-194 645.4 0.0 9.8e-185 614.4 0.0 2.2 2 0 0 2 2 2 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.21 KXS19208.1 - 0.0001 21.7 0.0 0.0004 19.8 0.0 2.0 1 0 0 1 1 1 1 Beta-eliminating lyase Pkinase PF00069.25 KXS19209.1 - 4e-35 121.5 0.0 4.9e-35 121.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS19209.1 - 7.1e-18 64.8 0.0 1e-17 64.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXS19209.1 - 0.00012 21.5 0.0 0.00099 18.5 0.0 1.9 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 KXS19209.1 - 0.23 10.8 0.1 0.4 10.0 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KXS19210.1 - 2.8e-06 26.9 0.0 3.9e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Prenyltransf PF01255.19 KXS19212.1 - 1.1e-77 260.6 0.0 1.2e-77 260.4 0.0 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Vps26 PF03643.15 KXS19212.1 - 0.026 13.5 0.0 0.043 12.8 0.0 1.3 1 0 0 1 1 1 0 Vacuolar protein sorting-associated protein 26 MS_channel PF00924.18 KXS19212.1 - 0.17 11.4 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel UBA PF00627.31 KXS19213.1 - 2.3e-28 97.6 6.5 1.1e-14 53.9 0.4 2.4 2 0 0 2 2 2 2 UBA/TS-N domain XPC-binding PF09280.11 KXS19213.1 - 1.4e-25 88.8 15.3 2.6e-25 87.9 15.3 1.5 1 0 0 1 1 1 1 XPC-binding domain ubiquitin PF00240.23 KXS19213.1 - 1.5e-22 79.1 0.8 2.6e-22 78.4 0.8 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KXS19213.1 - 4.6e-10 39.2 2.2 8e-10 38.4 2.2 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA_3 PF09288.10 KXS19213.1 - 6.5e-05 22.7 0.0 0.014 15.2 0.0 2.5 2 0 0 2 2 2 1 Fungal ubiquitin-associated domain Ubiquitin_2 PF14560.6 KXS19213.1 - 0.0013 19.2 0.2 0.0037 17.7 0.2 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 KXS19213.1 - 0.02 15.0 0.0 0.041 14.0 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like UBA_2 PF08587.11 KXS19213.1 - 0.052 13.7 0.1 1 9.5 0.0 2.4 2 0 0 2 2 2 0 Ubiquitin associated domain (UBA) Transmemb_17 PF09799.9 KXS19214.1 - 3.8e-12 46.8 0.8 5.9e-12 46.1 0.8 1.3 1 0 0 1 1 1 1 Predicted membrane protein AAA_6 PF12774.7 KXS19215.1 - 1.1e-151 504.4 0.0 4.1e-151 502.5 0.0 2.1 2 0 0 2 2 1 1 Hydrolytic ATP binding site of dynein motor region DHC_N1 PF08385.12 KXS19215.1 - 7.9e-150 500.2 3.7 7.9e-150 500.2 3.7 5.2 5 1 1 6 6 6 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 KXS19215.1 - 7.2e-125 417.2 6.0 7.2e-125 417.2 6.0 5.0 5 1 1 6 6 5 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 KXS19215.1 - 7.1e-91 304.1 0.2 4e-88 295.1 0.0 3.6 3 0 0 3 3 3 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 KXS19215.1 - 8.6e-88 293.1 4.8 7e-87 290.2 1.4 3.4 3 0 0 3 3 2 1 ATP-binding dynein motor region Dynein_C PF18199.1 KXS19215.1 - 5.3e-75 252.5 3.2 3.3e-73 246.6 0.0 4.1 5 0 0 5 5 4 1 Dynein heavy chain C-terminal domain AAA_7 PF12775.7 KXS19215.1 - 7.5e-69 230.9 1.7 9.6e-63 211.0 0.0 4.4 4 0 0 4 4 4 2 P-loop containing dynein motor region MT PF12777.7 KXS19215.1 - 3.3e-52 177.6 9.3 3.3e-52 177.6 9.3 1.8 2 0 0 2 2 1 1 Microtubule-binding stalk of dynein motor AAA_lid_11 PF18198.1 KXS19215.1 - 1.5e-48 164.7 0.0 5.5e-48 162.9 0.0 2.0 2 0 0 2 2 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 KXS19215.1 - 1.2e-46 157.6 0.0 1e-43 148.2 0.0 4.5 4 0 0 4 4 4 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 KXS19215.1 - 1e-29 103.2 0.9 8.4e-29 100.3 0.7 2.7 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 KXS19215.1 - 3.9e-28 98.2 0.0 7.6e-10 38.9 0.0 5.7 5 1 0 5 5 4 3 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 KXS19215.1 - 2.4e-18 66.2 2.1 8.2e-18 64.5 0.0 2.9 3 0 0 3 3 2 1 AAA+ lid domain AAA PF00004.29 KXS19215.1 - 1.1e-10 42.1 0.2 0.0091 16.4 0.0 5.3 5 0 0 5 5 4 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KXS19215.1 - 3.6e-08 34.0 8.5 0.033 14.6 0.1 6.7 6 1 1 7 7 6 2 AAA ATPase domain AAA_22 PF13401.6 KXS19215.1 - 5.6e-08 33.1 0.3 1.1 9.5 0.0 5.3 4 0 0 4 4 4 2 AAA domain DUF815 PF05673.13 KXS19215.1 - 6.7e-07 28.7 1.1 0.054 12.7 0.0 3.6 3 0 0 3 3 3 2 Protein of unknown function (DUF815) FtsK_SpoIIIE PF01580.18 KXS19215.1 - 8.6e-06 25.3 0.5 0.032 13.6 0.1 3.0 3 0 0 3 3 2 2 FtsK/SpoIIIE family AAA_29 PF13555.6 KXS19215.1 - 1.1e-05 25.1 2.8 0.13 12.1 0.1 3.4 3 0 0 3 3 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KXS19215.1 - 1.8e-05 24.7 2.9 0.023 14.6 0.1 2.9 2 0 0 2 2 2 2 RsgA GTPase Sigma54_activat PF00158.26 KXS19215.1 - 2e-05 24.4 0.3 0.045 13.5 0.1 2.7 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_18 PF13238.6 KXS19215.1 - 5.1e-05 23.8 0.1 0.67 10.5 0.0 4.0 4 0 0 4 4 2 2 AAA domain AAA_30 PF13604.6 KXS19215.1 - 5.7e-05 22.9 1.6 3.5 7.3 0.0 3.7 3 0 0 3 3 3 1 AAA domain T2SSE PF00437.20 KXS19215.1 - 0.00011 21.4 1.1 0.22 10.6 0.3 2.6 2 0 0 2 2 2 2 Type II/IV secretion system protein RNA_helicase PF00910.22 KXS19215.1 - 0.00013 22.3 1.1 5.6 7.4 0.1 4.0 3 0 0 3 3 3 0 RNA helicase ABC_tran PF00005.27 KXS19215.1 - 0.00046 20.7 12.3 0.038 14.5 0.5 5.0 5 0 0 5 5 2 2 ABC transporter AAA_33 PF13671.6 KXS19215.1 - 0.00084 19.5 0.5 4.3 7.5 0.0 3.8 3 0 0 3 3 3 0 AAA domain SMC_N PF02463.19 KXS19215.1 - 0.0041 16.6 1.6 1.7 8.0 0.5 3.4 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain Roc PF08477.13 KXS19215.1 - 0.0049 17.1 3.1 0.13 12.5 0.1 3.8 3 0 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KXS19215.1 - 0.0052 16.9 6.1 0.74 9.9 0.1 3.6 4 0 0 4 4 2 2 50S ribosome-binding GTPase Zeta_toxin PF06414.12 KXS19215.1 - 0.0056 16.0 1.8 3.1 7.0 0.1 2.9 2 0 0 2 2 2 2 Zeta toxin Mg_chelatase PF01078.21 KXS19215.1 - 0.0067 15.8 0.3 1.8 7.9 0.0 3.4 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI Septin PF00735.18 KXS19215.1 - 0.01 15.1 0.5 4.6 6.4 0.1 2.7 2 0 0 2 2 2 0 Septin TrwB_AAD_bind PF10412.9 KXS19215.1 - 0.011 14.7 0.9 1.9 7.3 0.3 2.8 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain TsaE PF02367.17 KXS19215.1 - 0.013 15.5 2.0 11 6.1 0.0 3.7 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Spectrin PF00435.21 KXS19215.1 - 0.021 15.3 0.3 0.021 15.3 0.3 7.4 7 2 1 8 8 5 0 Spectrin repeat Pox_A32 PF04665.12 KXS19215.1 - 0.038 13.5 0.6 0.59 9.5 0.0 2.8 2 0 0 2 2 2 0 Poxvirus A32 protein Rad17 PF03215.15 KXS19215.1 - 0.046 13.6 1.2 22 4.9 0.0 3.8 3 0 0 3 3 3 0 Rad17 P-loop domain NACHT PF05729.12 KXS19215.1 - 0.063 13.2 5.4 3.4 7.6 0.1 4.2 3 0 0 3 3 3 0 NACHT domain AAA_24 PF13479.6 KXS19215.1 - 0.15 11.7 6.3 43 3.7 0.0 4.9 5 0 0 5 5 4 0 AAA domain AAA_21 PF13304.6 KXS19215.1 - 0.53 10.0 2.6 9.6 5.9 0.0 3.1 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF87 PF01935.17 KXS19215.1 - 0.85 9.7 9.9 5.1 7.1 0.1 5.1 4 0 0 4 4 4 0 Helicase HerA, central domain KxDL PF10241.9 KXS19215.1 - 1.1 9.6 13.9 2 8.7 1.2 5.2 4 0 0 4 4 3 0 Uncharacterized conserved protein IIGP PF05049.13 KXS19215.1 - 1.9 7.5 10.6 1.1 8.3 0.2 3.7 4 0 0 4 4 4 0 Interferon-inducible GTPase (IIGP) AAA PF00004.29 KXS19216.1 - 9.8e-46 155.4 0.1 8.2e-45 152.5 0.0 2.2 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KXS19216.1 - 2.6e-10 39.9 0.1 5.4e-10 38.9 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 KXS19216.1 - 2e-09 37.5 0.1 6e-09 36.0 0.1 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Prot_ATP_ID_OB PF16450.5 KXS19216.1 - 2.5e-09 36.9 0.2 2.1e-08 34.0 0.0 2.5 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_16 PF13191.6 KXS19216.1 - 2e-08 34.8 0.4 2.5e-05 24.7 0.0 2.9 2 2 0 3 3 3 1 AAA ATPase domain AAA_2 PF07724.14 KXS19216.1 - 7.7e-08 32.6 0.1 2.1e-07 31.2 0.0 1.8 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 KXS19216.1 - 1.8e-06 27.3 0.0 3.6e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 KXS19216.1 - 0.00017 22.1 0.1 0.001 19.6 0.0 2.2 3 0 0 3 3 2 1 AAA domain AAA_22 PF13401.6 KXS19216.1 - 0.00028 21.2 3.4 0.015 15.6 1.0 2.7 2 1 0 2 2 1 1 AAA domain AAA_7 PF12775.7 KXS19216.1 - 0.0005 19.6 0.1 0.0042 16.6 0.1 2.0 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_28 PF13521.6 KXS19216.1 - 0.00058 20.1 0.1 0.0012 19.1 0.0 1.6 2 0 0 2 2 1 1 AAA domain RuvB_N PF05496.12 KXS19216.1 - 0.0008 19.2 0.0 0.0021 17.8 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 KXS19216.1 - 0.001 19.0 0.0 0.015 15.3 0.0 2.2 1 1 1 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 KXS19216.1 - 0.0017 18.4 0.0 0.0057 16.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 KXS19216.1 - 0.0019 18.1 0.1 0.0094 15.9 0.0 2.2 3 0 0 3 3 3 1 NTPase AAA_30 PF13604.6 KXS19216.1 - 0.0033 17.2 0.0 0.0085 15.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KXS19216.1 - 0.0037 17.6 0.0 0.0083 16.5 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_11 PF13086.6 KXS19216.1 - 0.005 16.7 0.1 0.1 12.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KXS19216.1 - 0.0063 16.7 0.0 0.017 15.2 0.0 1.8 2 0 0 2 2 1 1 AAA domain Mg_chelatase PF01078.21 KXS19216.1 - 0.008 15.6 0.0 0.019 14.4 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 KXS19216.1 - 0.0094 15.7 0.0 0.028 14.2 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.13 KXS19216.1 - 0.01 15.1 0.0 0.019 14.2 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_3 PF07726.11 KXS19216.1 - 0.01 15.7 0.0 0.026 14.4 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 KXS19216.1 - 0.013 15.4 0.1 0.078 12.9 0.0 2.1 2 0 0 2 2 2 0 NACHT domain TniB PF05621.11 KXS19216.1 - 0.013 14.9 0.1 0.62 9.4 0.0 2.5 3 0 0 3 3 2 0 Bacterial TniB protein AAA_25 PF13481.6 KXS19216.1 - 0.023 14.3 1.3 0.049 13.2 0.1 2.0 2 1 0 2 2 2 0 AAA domain AAA_19 PF13245.6 KXS19216.1 - 0.024 15.0 0.1 0.13 12.6 0.1 2.1 2 0 0 2 2 1 0 AAA domain ATPase PF06745.13 KXS19216.1 - 0.024 14.0 1.2 0.55 9.5 0.0 2.8 3 0 0 3 3 3 0 KaiC ATPase_2 PF01637.18 KXS19216.1 - 0.024 14.5 1.0 0.73 9.7 0.0 2.9 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea AAA_24 PF13479.6 KXS19216.1 - 0.025 14.3 0.1 0.06 13.1 0.1 1.6 1 1 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 KXS19216.1 - 0.056 13.1 0.3 1.2 8.8 0.0 2.8 3 1 0 3 3 2 0 Sigma-54 interaction domain AFG1_ATPase PF03969.16 KXS19216.1 - 0.089 11.7 0.0 0.15 10.9 0.0 1.4 1 0 0 1 1 1 0 AFG1-like ATPase SPACA9 PF15120.6 KXS19216.1 - 0.097 12.4 0.3 7.3 6.3 0.1 2.2 2 0 0 2 2 2 0 Sperm acrosome-associated protein 9 Bac_DnaA PF00308.18 KXS19216.1 - 0.11 12.4 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Bacterial dnaA protein cobW PF02492.19 KXS19216.1 - 0.12 11.9 0.0 0.24 11.0 0.0 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Parvo_NS1 PF01057.17 KXS19216.1 - 0.14 11.2 0.0 0.27 10.3 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ABC_tran PF00005.27 KXS19216.1 - 0.14 12.6 0.1 0.6 10.6 0.0 2.3 2 1 0 2 2 2 0 ABC transporter AAA_29 PF13555.6 KXS19216.1 - 0.2 11.5 0.0 0.4 10.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 KXS19216.1 - 2.5 8.5 7.1 10 6.6 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.6 KXS19217.1 - 2.3e-30 106.6 41.6 5.5e-29 102.1 16.0 3.4 1 1 1 2 2 1 1 AAA domain AAA_15 PF13175.6 KXS19217.1 - 2.1e-11 44.2 24.1 6.8e-09 35.9 24.1 2.7 1 1 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 KXS19217.1 - 6.5e-11 42.1 16.0 7.8e-10 38.5 16.0 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KXS19217.1 - 1.2e-10 41.7 8.2 0.00024 21.0 7.9 3.1 2 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 KXS19217.1 - 1.9e-06 28.0 0.0 5.8e-06 26.5 0.0 1.9 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 KXS19217.1 - 0.0016 18.1 0.0 0.0033 17.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 KXS19217.1 - 0.043 14.3 0.0 0.043 14.3 0.0 4.7 2 1 0 2 2 1 0 ABC transporter GTP_EFTU PF00009.27 KXS19217.1 - 0.13 11.7 0.7 0.43 10.1 0.0 2.1 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_33 PF13671.6 KXS19217.1 - 0.15 12.2 2.6 0.3 11.3 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_22 PF13401.6 KXS19217.1 - 0.23 11.8 0.1 0.23 11.8 0.1 2.5 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KXS19217.1 - 1 9.7 12.7 0.46 10.8 4.0 3.6 2 1 0 3 3 3 0 AAA ATPase domain DUF948 PF06103.11 KXS19217.1 - 7.6 6.9 6.5 45 4.4 0.4 3.7 3 2 1 4 4 4 0 Bacterial protein of unknown function (DUF948) SLC3A2_N PF16028.5 KXS19218.1 - 0.024 14.2 0.0 0.032 13.8 0.0 1.3 1 0 0 1 1 1 0 Solute carrier family 3 member 2 N-terminus Xpo1 PF08389.12 KXS19219.1 - 0.062 13.3 0.0 0.27 11.3 0.0 2.1 2 0 0 2 2 2 0 Exportin 1-like protein E1_4HB PF16191.5 KXS19219.1 - 0.12 12.6 0.0 0.29 11.3 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-activating enzyme E1 four-helix bundle HemY_N PF07219.13 KXS19220.1 - 0.17 12.1 3.1 7.3 6.8 0.0 2.6 2 0 0 2 2 2 0 HemY protein N-terminus Ost5 PF05251.12 KXS19223.1 - 1.1e-16 60.9 2.1 1.2e-16 60.8 2.1 1.1 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit 5 PEP-CTERM PF07589.11 KXS19223.1 - 5.5 7.2 8.3 20 5.5 0.2 2.4 2 0 0 2 2 2 0 PEP-CTERM motif DHFR_1 PF00186.19 KXS19224.1 - 7.9e-25 87.4 0.0 1.3e-15 57.5 0.0 3.1 3 0 0 3 3 3 3 Dihydrofolate reductase AA_permease_2 PF13520.6 KXS19225.1 - 1.2e-19 70.4 16.9 1.6e-19 70.1 16.9 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXS19225.1 - 7.5e-11 41.3 13.0 7.5e-11 41.3 13.0 1.3 1 1 0 1 1 1 1 Amino acid permease Snf7 PF03357.21 KXS19228.1 - 5.8e-15 55.3 3.4 8.9e-15 54.7 3.4 1.2 1 0 0 1 1 1 1 Snf7 Spectrin PF00435.21 KXS19228.1 - 0.14 12.6 0.4 0.14 12.6 0.4 2.2 2 0 0 2 2 2 0 Spectrin repeat Glyco_trans_1_4 PF13692.6 KXS19229.1 - 7.4e-18 65.3 0.0 1.2e-17 64.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 KXS19229.1 - 0.00079 19.8 0.0 0.0014 19.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KXS19229.1 - 0.092 12.7 0.0 11 6.0 0.0 2.3 2 0 0 2 2 2 0 Glycosyltransferase Family 4 Methyltransf_22 PF13383.6 KXS19230.1 - 1.5e-10 41.1 0.7 2.1e-10 40.6 0.7 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.12 KXS19230.1 - 0.0012 18.9 0.0 0.0017 18.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase FkbM domain Hus1 PF04005.12 KXS19231.1 - 5.4e-71 239.1 0.0 6.1e-71 238.9 0.0 1.0 1 0 0 1 1 1 1 Hus1-like protein HPTransfase PF10090.9 KXS19231.1 - 0.14 11.9 0.1 0.37 10.6 0.0 1.7 2 0 0 2 2 2 0 Histidine phosphotransferase C-terminal domain TM231 PF10149.9 KXS19232.1 - 2.1e-40 138.9 0.0 2.5e-40 138.7 0.0 1.0 1 0 0 1 1 1 1 Transmembrane protein 231 DUF2647 PF10839.8 KXS19232.1 - 0.13 12.3 0.1 1.9 8.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2647) Peptidase_M50B PF13398.6 KXS19235.1 - 7.1e-51 172.7 18.9 8.8e-51 172.4 18.9 1.1 1 0 0 1 1 1 1 Peptidase M50B-like CBM_21 PF03370.13 KXS19236.1 - 7.7e-20 71.2 0.0 3.1e-19 69.2 0.0 1.9 1 1 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 KXS19236.1 - 0.0042 17.7 0.1 1.1 9.9 0.1 2.5 2 0 0 2 2 2 2 Starch/carbohydrate-binding module (family 53) Nop14 PF04147.12 KXS19236.1 - 1.5 6.9 3.3 2.2 6.4 3.3 1.1 1 0 0 1 1 1 0 Nop14-like family Methyltransf_24 PF13578.6 KXS19237.1 - 0.0082 17.2 0.0 0.019 16.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain XG_FTase PF03254.13 KXS19238.1 - 0.00022 20.0 0.0 0.00041 19.1 0.0 1.4 1 0 0 1 1 1 1 Xyloglucan fucosyltransferase NodZ PF05830.11 KXS19238.1 - 0.099 11.4 0.2 3.6 6.3 0.2 2.1 1 1 0 1 1 1 0 Nodulation protein Z (NodZ) Glyco_transf_90 PF05686.12 KXS19239.1 - 4.6e-18 65.3 0.0 9.6e-18 64.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 90 Mannosyl_trans3 PF11051.8 KXS19240.1 - 1.7e-39 135.8 0.0 2.6e-39 135.2 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative XG_FTase PF03254.13 KXS19242.1 - 7.7e-10 38.0 0.4 0.00011 21.0 0.0 2.6 2 1 0 2 2 2 2 Xyloglucan fucosyltransferase PAP_assoc PF03828.19 KXS19242.1 - 0.19 12.0 1.2 12 6.2 0.0 2.6 2 0 0 2 2 2 0 Cid1 family poly A polymerase Nucleotid_trans PF03407.16 KXS19243.1 - 5.2e-26 91.9 0.0 6.6e-26 91.6 0.0 1.1 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Mannosyl_trans3 PF11051.8 KXS19244.1 - 3.7e-39 134.7 0.0 5.3e-39 134.2 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative Nucleotid_trans PF03407.16 KXS19244.1 - 0.068 13.1 0.4 0.21 11.5 0.4 1.8 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase Methyltransf_22 PF13383.6 KXS19246.1 - 8.5e-14 51.7 0.0 1.6e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.12 KXS19246.1 - 2.6e-07 30.8 0.0 4.4e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase FkbM domain Methyltransf_22 PF13383.6 KXS19247.1 - 1.5e-12 47.6 1.4 2.3e-12 47.0 0.3 1.9 2 1 1 3 3 3 1 Methyltransferase domain Methyltransf_21 PF05050.12 KXS19247.1 - 4.4e-05 23.6 0.0 7.4e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase FkbM domain CbtB PF09489.10 KXS19247.1 - 0.093 12.8 0.2 0.17 12.0 0.2 1.4 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtB) Glycos_transf_2 PF00535.26 KXS19248.1 - 2.3e-27 95.9 0.0 4e-27 95.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KXS19248.1 - 8.2e-16 58.6 0.0 1.8e-15 57.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 KXS19248.1 - 3e-11 43.3 0.0 9.8e-10 38.3 0.0 2.2 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 KXS19248.1 - 0.0043 17.5 0.0 0.013 16.0 0.0 1.9 1 0 0 1 1 1 1 Glycosyl transferase family 2 TPR_2 PF07719.17 KXS19248.1 - 0.011 15.8 0.1 0.56 10.5 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 KXS19248.1 - 0.026 14.7 0.0 0.25 11.7 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Laminin_G_3 PF13385.6 KXS19248.1 - 0.058 13.5 0.0 0.16 12.1 0.0 1.8 1 0 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily Glyco_transf_7C PF02709.14 KXS19248.1 - 0.068 12.8 0.1 0.17 11.6 0.1 1.6 1 0 0 1 1 1 0 N-terminal domain of galactosyltransferase Rhamno_transf PF11316.8 KXS19248.1 - 0.069 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Putative rhamnosyl transferase TPR_17 PF13431.6 KXS19248.1 - 0.1 13.0 2.4 0.45 11.0 0.0 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Gly_transf_sug PF04488.15 KXS19249.1 - 0.002 18.7 0.0 0.0039 17.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Laminin_G_3 PF13385.6 KXS19249.1 - 0.13 12.4 0.0 1.1 9.4 0.0 2.3 2 1 0 2 2 2 0 Concanavalin A-like lectin/glucanases superfamily Methyltransf_24 PF13578.6 KXS19250.1 - 3e-09 37.8 0.0 4.5e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Proteasom_Rpn13 PF04683.13 KXS19251.1 - 2.5e-27 95.2 0.1 4.6e-27 94.4 0.1 1.4 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor RPN13_C PF16550.5 KXS19251.1 - 3.4e-19 69.1 1.3 2.2e-18 66.5 1.3 2.0 1 1 0 1 1 1 1 UCH-binding domain HsbA PF12296.8 KXS19251.1 - 0.11 12.9 0.2 0.33 11.4 0.2 1.8 1 0 0 1 1 1 0 Hydrophobic surface binding protein A Glyco_transf_8 PF01501.20 KXS19252.1 - 7.1e-09 35.6 5.2 2.3e-08 33.9 5.2 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 8 Nucleotid_trans PF03407.16 KXS19252.1 - 0.0029 17.6 0.1 0.0048 16.9 0.1 1.3 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Mannosyl_trans3 PF11051.8 KXS19252.1 - 0.18 11.1 0.1 0.27 10.5 0.1 1.2 1 0 0 1 1 1 0 Mannosyltransferase putative Mannosyl_trans3 PF11051.8 KXS19253.1 - 1.1e-42 146.3 0.0 1.6e-42 145.8 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative Exostosin PF03016.15 KXS19254.1 - 1.4e-23 83.6 0.4 1.8e-22 80.0 0.0 2.7 2 1 0 2 2 2 1 Exostosin family Exonuc_V_gamma PF04257.14 KXS19254.1 - 0.13 10.5 0.0 0.18 10.0 0.0 1.1 1 0 0 1 1 1 0 Exodeoxyribonuclease V, gamma subunit Methyltransf_22 PF13383.6 KXS19255.1 - 3.1e-25 89.2 0.1 4e-25 88.8 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.12 KXS19255.1 - 9.1e-07 29.1 0.0 1.2e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase FkbM domain NDUF_B12 PF08122.12 KXS19256.1 - 1.8e-13 50.3 1.3 2.1e-13 50.1 1.3 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family Methyltransf_22 PF13383.6 KXS19258.1 - 2.9e-17 63.1 0.4 7.7e-17 61.7 0.4 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.12 KXS19258.1 - 4.1e-10 39.9 0.0 6.7e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase FkbM domain Meth_synt_2 PF01717.18 KXS19259.1 - 1.8e-160 533.5 0.0 5.4e-153 509.0 0.0 2.1 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 KXS19259.1 - 6.5e-118 393.8 0.0 7.7e-109 364.0 0.0 2.8 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain V-ATPase_H_N PF03224.14 KXS19260.1 - 1.9e-57 195.0 0.0 4.3e-57 193.8 0.0 1.5 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 KXS19260.1 - 2.4e-45 153.4 1.8 6.7e-45 152.0 0.8 2.2 3 0 0 3 3 3 1 V-ATPase subunit H Arm PF00514.23 KXS19260.1 - 4.1e-07 29.8 0.3 2.1 8.5 0.0 5.0 5 0 0 5 5 5 3 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 KXS19260.1 - 0.00033 21.0 0.0 0.12 12.8 0.0 2.9 2 0 0 2 2 2 2 HEAT repeats HEAT PF02985.22 KXS19260.1 - 0.012 15.8 0.0 9.1 6.8 0.0 3.5 3 0 0 3 3 3 0 HEAT repeat PTPS PF01242.19 KXS19261.1 - 2.3e-32 111.5 1.8 3.7e-30 104.4 0.5 2.1 2 0 0 2 2 2 2 6-pyruvoyl tetrahydropterin synthase TPK_catalytic PF04263.16 KXS19261.1 - 0.051 13.6 0.0 0.09 12.8 0.0 1.4 1 0 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain Tropomyosin_1 PF12718.7 KXS19262.1 - 9.7e-07 29.0 17.3 9.7e-07 29.0 17.3 2.9 1 1 2 3 3 3 1 Tropomyosin like IFT57 PF10498.9 KXS19262.1 - 3.3e-05 23.0 11.6 3.3e-05 23.0 11.6 2.0 1 1 1 2 2 2 1 Intra-flagellar transport protein 57 TPR_MLP1_2 PF07926.12 KXS19262.1 - 0.00031 20.8 31.7 0.00099 19.2 25.8 2.8 1 1 1 2 2 2 1 TPR/MLP1/MLP2-like protein Cnn_1N PF07989.11 KXS19262.1 - 0.00042 20.4 29.1 0.11 12.7 5.5 3.3 2 1 1 3 3 3 2 Centrosomin N-terminal motif 1 BLOC1_2 PF10046.9 KXS19262.1 - 0.00077 19.7 20.7 0.00091 19.5 8.6 2.8 2 1 0 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 FlaC_arch PF05377.11 KXS19262.1 - 0.00083 19.7 17.7 0.15 12.5 1.4 3.8 3 1 0 3 3 3 2 Flagella accessory protein C (FlaC) LPP PF04728.13 KXS19262.1 - 0.0011 19.3 0.5 0.0011 19.3 0.5 4.2 3 2 0 3 3 2 1 Lipoprotein leucine-zipper BST2 PF16716.5 KXS19262.1 - 0.0011 19.5 25.3 0.0015 19.1 7.4 3.4 2 1 1 3 3 3 1 Bone marrow stromal antigen 2 Baculo_PEP_C PF04513.12 KXS19262.1 - 0.0016 18.5 5.4 0.081 13.0 0.1 2.3 1 1 1 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 KXS19262.1 - 0.0022 18.0 18.4 0.0024 17.9 7.7 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF1664) UPF0242 PF06785.11 KXS19262.1 - 0.0023 18.1 13.9 0.0023 18.1 13.9 2.1 1 1 1 2 2 2 1 Uncharacterised protein family (UPF0242) N-terminus Prefoldin_2 PF01920.20 KXS19262.1 - 0.0023 17.9 30.2 0.0091 15.9 6.8 4.0 2 2 2 4 4 4 1 Prefoldin subunit Phage_GP20 PF06810.11 KXS19262.1 - 0.0024 17.7 26.3 0.016 15.1 16.6 3.4 1 1 2 3 3 3 1 Phage minor structural protein GP20 ATG16 PF08614.11 KXS19262.1 - 0.0025 18.1 29.0 0.004 17.4 29.0 1.3 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) ADIP PF11559.8 KXS19262.1 - 0.003 17.7 7.8 0.003 17.7 7.8 3.1 1 1 2 3 3 3 1 Afadin- and alpha -actinin-Binding HALZ PF02183.18 KXS19262.1 - 0.0034 17.6 21.1 1.6 9.0 2.4 4.8 3 2 1 4 4 4 0 Homeobox associated leucine zipper GCP_N_terminal PF17681.1 KXS19262.1 - 0.0039 16.9 2.0 0.0051 16.5 2.0 1.2 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal Fzo_mitofusin PF04799.13 KXS19262.1 - 0.0042 16.7 9.1 0.0042 16.7 9.1 3.2 1 1 3 4 4 4 2 fzo-like conserved region Taxilin PF09728.9 KXS19262.1 - 0.0045 16.2 11.9 0.0045 16.2 11.9 2.2 1 1 1 2 2 2 1 Myosin-like coiled-coil protein MscS_porin PF12795.7 KXS19262.1 - 0.0053 16.3 28.2 0.023 14.3 12.3 2.2 1 1 1 2 2 2 1 Mechanosensitive ion channel porin domain FliD_C PF07195.12 KXS19262.1 - 0.0058 16.1 10.2 0.019 14.4 2.0 2.1 1 1 1 2 2 2 1 Flagellar hook-associated protein 2 C-terminus DUF3450 PF11932.8 KXS19262.1 - 0.0064 15.8 6.1 0.0064 15.8 6.1 3.0 1 1 2 3 3 3 1 Protein of unknown function (DUF3450) SlyX PF04102.12 KXS19262.1 - 0.0064 17.1 29.2 0.29 11.8 10.4 3.9 1 1 2 3 3 3 1 SlyX CCDC92 PF14916.6 KXS19262.1 - 0.0069 16.1 2.1 0.0069 16.1 2.1 2.9 2 1 1 3 3 2 1 Coiled-coil domain of unknown function HMMR_N PF15905.5 KXS19262.1 - 0.0083 15.6 27.5 0.013 15.0 27.5 1.3 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal DASH_Hsk3 PF08227.11 KXS19262.1 - 0.0091 16.3 0.3 0.0091 16.3 0.3 4.3 3 2 0 4 4 3 1 DASH complex subunit Hsk3 like FlxA PF14282.6 KXS19262.1 - 0.0098 15.9 25.9 0.31 11.1 8.5 3.0 1 1 1 2 2 2 1 FlxA-like protein DUF4407 PF14362.6 KXS19262.1 - 0.014 14.7 22.3 0.033 13.5 22.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) ZapB PF06005.12 KXS19262.1 - 0.016 15.6 36.8 0.61 10.6 7.8 3.7 1 1 3 4 4 4 0 Cell division protein ZapB GAS PF13851.6 KXS19262.1 - 0.017 14.5 30.2 0.033 13.5 22.4 2.9 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.9 KXS19262.1 - 0.019 15.0 32.8 0.041 13.9 23.4 2.4 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tektin PF03148.14 KXS19262.1 - 0.02 13.7 26.4 0.056 12.2 26.4 1.7 1 1 0 1 1 1 0 Tektin family NPV_P10 PF05531.12 KXS19262.1 - 0.023 15.1 9.9 0.63 10.5 0.3 2.8 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein DivIC PF04977.15 KXS19262.1 - 0.026 14.3 5.0 0.026 14.3 5.0 4.4 1 1 0 3 3 2 0 Septum formation initiator Csm1_N PF18504.1 KXS19262.1 - 0.027 14.8 29.3 0.31 11.4 4.2 4.4 2 2 2 4 4 4 0 Csm1 N-terminal domain Spc7 PF08317.11 KXS19262.1 - 0.028 13.3 34.0 0.023 13.6 15.9 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein Cob_adeno_trans PF01923.18 KXS19262.1 - 0.032 14.4 13.5 0.045 13.9 4.2 2.2 1 1 1 2 2 2 0 Cobalamin adenosyltransferase Exonuc_VII_L PF02601.15 KXS19262.1 - 0.033 13.8 14.9 0.048 13.2 14.9 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit FPP PF05911.11 KXS19262.1 - 0.034 12.4 29.6 0.096 10.9 29.6 1.6 1 1 0 1 1 1 0 Filament-like plant protein, long coiled-coil Fib_alpha PF08702.10 KXS19262.1 - 0.034 14.3 17.4 0.097 12.9 6.7 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF2203 PF09969.9 KXS19262.1 - 0.035 14.8 20.8 0.51 11.1 7.4 2.2 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) CorA PF01544.18 KXS19262.1 - 0.039 13.3 17.9 0.025 13.9 6.9 2.2 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein CALCOCO1 PF07888.11 KXS19262.1 - 0.043 12.7 28.6 0.066 12.1 28.6 1.2 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF4200 PF13863.6 KXS19262.1 - 0.05 14.0 33.6 0.12 12.8 15.2 3.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) FapA PF03961.13 KXS19262.1 - 0.052 12.2 23.0 0.021 13.5 10.0 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A Rootletin PF15035.6 KXS19262.1 - 0.053 13.5 25.9 0.61 10.1 9.8 2.2 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion DUF4618 PF15397.6 KXS19262.1 - 0.054 12.9 23.3 0.28 10.6 23.4 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) COG5 PF10392.9 KXS19262.1 - 0.057 13.6 9.6 0.44 10.7 3.9 2.7 1 1 1 2 2 2 0 Golgi transport complex subunit 5 Occludin_ELL PF07303.13 KXS19262.1 - 0.058 14.1 16.7 0.16 12.7 4.6 2.5 1 1 2 3 3 3 0 Occludin homology domain PRKG1_interact PF15898.5 KXS19262.1 - 0.061 14.2 29.6 5.6 7.9 3.7 3.3 1 1 0 2 2 2 0 cGMP-dependent protein kinase interacting domain Rab5-bind PF09311.11 KXS19262.1 - 0.065 12.6 25.4 0.61 9.4 12.3 2.1 1 1 1 2 2 2 0 Rabaptin-like protein DUF2935 PF11155.8 KXS19262.1 - 0.078 13.3 8.0 0.15 12.4 0.5 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) Laminin_II PF06009.12 KXS19262.1 - 0.087 12.8 17.0 0.11 12.5 1.9 2.8 1 1 2 3 3 3 0 Laminin Domain II DUF713 PF05218.14 KXS19262.1 - 0.091 12.5 12.4 0.21 11.3 10.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF713) DUF4686 PF15742.5 KXS19262.1 - 0.092 11.9 30.1 0.39 9.8 30.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4686) Seryl_tRNA_N PF02403.22 KXS19262.1 - 0.098 12.9 30.0 0.42 10.9 10.7 4.0 1 1 3 4 4 4 0 Seryl-tRNA synthetase N-terminal domain DUF1192 PF06698.11 KXS19262.1 - 0.1 12.7 28.9 0.58 10.3 3.1 4.1 3 1 0 4 4 3 0 Protein of unknown function (DUF1192) TMF_TATA_bd PF12325.8 KXS19262.1 - 0.1 12.8 32.2 0.091 13.0 21.2 2.7 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding FH2 PF02181.23 KXS19262.1 - 0.11 11.6 20.3 0.42 9.7 6.8 2.1 1 1 1 2 2 2 0 Formin Homology 2 Domain DUF3584 PF12128.8 KXS19262.1 - 0.11 9.9 28.6 0.22 9.0 28.6 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) Jnk-SapK_ap_N PF09744.9 KXS19262.1 - 0.12 12.6 35.2 0.19 12.0 18.1 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 WXG100 PF06013.12 KXS19262.1 - 0.13 12.5 16.9 2.8 8.2 6.5 4.0 1 1 2 3 3 3 0 Proteins of 100 residues with WXG HrpB7 PF09486.10 KXS19262.1 - 0.14 12.6 34.8 7.8 6.9 2.4 3.8 1 1 1 3 3 3 0 Bacterial type III secretion protein (HrpB7) Prominin PF05478.11 KXS19262.1 - 0.15 10.0 12.8 0.9 7.4 9.6 2.1 1 1 1 2 2 2 0 Prominin DUF3138 PF11336.8 KXS19262.1 - 0.16 10.6 5.5 0.24 10.0 5.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Uso1_p115_C PF04871.13 KXS19262.1 - 0.16 12.4 31.4 0.43 10.9 11.0 2.9 1 1 2 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region DHR10 PF18595.1 KXS19262.1 - 0.16 12.0 37.3 1.3 9.1 19.5 3.1 1 1 2 3 3 3 0 Designed helical repeat protein 10 domain Spectrin PF00435.21 KXS19262.1 - 0.17 12.4 27.1 0.13 12.7 9.6 2.3 1 1 1 2 2 2 0 Spectrin repeat Syntaxin-6_N PF09177.11 KXS19262.1 - 0.17 12.5 15.7 25 5.5 4.3 2.9 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Apolipoprotein PF01442.18 KXS19262.1 - 0.17 11.8 35.0 3.3 7.5 34.3 2.2 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain TMPIT PF07851.13 KXS19262.1 - 0.2 10.9 18.7 0.32 10.2 7.4 2.0 1 1 1 2 2 2 0 TMPIT-like protein DUF812 PF05667.11 KXS19262.1 - 0.22 10.4 28.2 0.5 9.2 28.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF812) AAA_13 PF13166.6 KXS19262.1 - 0.23 10.1 21.9 0.048 12.3 8.3 1.8 1 1 1 2 2 2 0 AAA domain Lebercilin PF15619.6 KXS19262.1 - 0.23 11.1 31.5 2.8 7.6 31.5 2.1 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease ABC_tran_CTD PF16326.5 KXS19262.1 - 0.24 11.7 40.0 3.6 7.9 15.8 3.9 1 1 1 2 2 2 0 ABC transporter C-terminal domain OmpH PF03938.14 KXS19262.1 - 0.24 11.7 33.7 0.16 12.3 15.6 2.5 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) CdvA PF18822.1 KXS19262.1 - 0.24 11.2 24.4 10 6.0 21.2 2.9 1 1 1 2 2 2 0 CdvA-like coiled-coil domain BORCS8 PF10167.9 KXS19262.1 - 0.32 10.9 12.1 0.35 10.8 4.4 2.4 1 1 1 2 2 2 0 BLOC-1-related complex sub-unit 8 V_ATPase_I PF01496.19 KXS19262.1 - 0.33 8.8 20.2 0.28 9.1 16.8 1.7 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family DHR-2 PF06920.13 KXS19262.1 - 0.34 9.5 11.2 0.055 12.1 5.1 1.9 1 1 1 2 2 2 0 Dock homology region 2 Laminin_I PF06008.14 KXS19262.1 - 0.35 10.5 25.5 0.64 9.7 5.8 2.6 1 1 1 2 2 2 0 Laminin Domain I Swi5 PF07061.11 KXS19262.1 - 0.36 10.9 24.2 20 5.3 8.6 4.1 1 1 0 2 2 2 0 Swi5 TolA_bind_tri PF16331.5 KXS19262.1 - 0.38 10.9 26.4 0.77 9.9 7.9 3.3 1 1 1 3 3 3 0 TolA binding protein trimerisation ARS2 PF04959.13 KXS19262.1 - 0.4 11.0 8.2 0.22 11.9 5.2 2.0 1 1 1 2 2 1 0 Arsenite-resistance protein 2 Atg14 PF10186.9 KXS19262.1 - 0.41 9.7 22.0 0.077 12.1 9.2 2.1 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF16 PF01519.16 KXS19262.1 - 0.43 11.1 18.5 18 5.9 16.0 2.9 1 1 1 2 2 2 0 Protein of unknown function DUF16 Lectin_N PF03954.14 KXS19262.1 - 0.48 10.2 8.6 9.1 6.0 8.0 2.7 1 1 0 1 1 1 0 Hepatic lectin, N-terminal domain BORCS7 PF16088.5 KXS19262.1 - 0.49 10.7 12.4 0.11 12.8 2.0 2.8 1 1 1 3 3 3 0 BLOC-1-related complex sub-unit 7 HemX PF04375.14 KXS19262.1 - 0.54 9.5 23.2 0.48 9.7 7.9 2.1 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase FliJ PF02050.16 KXS19262.1 - 0.55 10.5 30.2 0.34 11.1 10.7 2.9 1 1 1 2 2 2 0 Flagellar FliJ protein PspA_IM30 PF04012.12 KXS19262.1 - 0.57 9.7 33.7 18 4.9 33.7 2.5 1 1 0 1 1 1 0 PspA/IM30 family Bacillus_HBL PF05791.11 KXS19262.1 - 0.63 9.9 10.7 0.21 11.4 2.5 2.4 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) KASH_CCD PF14662.6 KXS19262.1 - 0.72 9.7 31.4 1.6 8.5 31.5 1.5 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Rx_N PF18052.1 KXS19262.1 - 0.74 10.1 28.2 0.042 14.1 8.6 3.4 1 1 2 3 3 3 0 Rx N-terminal domain DUF5082 PF16888.5 KXS19262.1 - 0.78 10.0 21.7 54 4.1 0.2 3.4 1 1 0 2 2 2 0 Domain of unknown function (DUF5082) DUF724 PF05266.14 KXS19262.1 - 0.8 9.5 28.6 0.096 12.5 13.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DUF4795 PF16043.5 KXS19262.1 - 0.83 9.2 29.2 4.4 6.8 12.5 2.6 1 1 0 2 2 2 0 Domain of unknown function (DUF4795) DUF2408 PF10303.9 KXS19262.1 - 0.85 10.2 19.0 6 7.4 18.1 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) THOC7 PF05615.13 KXS19262.1 - 1 9.7 33.0 2.2 8.5 12.8 3.5 1 1 1 2 2 2 0 Tho complex subunit 7 Golgin_A5 PF09787.9 KXS19262.1 - 1 8.8 33.2 2.1 7.7 15.3 2.1 1 1 1 2 2 2 0 Golgin subfamily A member 5 TMCO5 PF14992.6 KXS19262.1 - 1.1 8.8 28.7 0.072 12.7 17.7 2.0 1 1 1 2 2 2 0 TMCO5 family YabA PF06156.13 KXS19262.1 - 1.1 9.9 25.0 6.5 7.4 6.9 3.2 1 1 2 3 3 3 0 Initiation control protein YabA DUF948 PF06103.11 KXS19262.1 - 1.3 9.3 12.7 1.9 8.8 1.2 3.0 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) BRE1 PF08647.11 KXS19262.1 - 1.3 9.1 30.9 5.8 7.1 11.3 3.2 1 1 2 3 3 3 0 BRE1 E3 ubiquitin ligase HIP1_clath_bdg PF16515.5 KXS19262.1 - 1.4 9.6 34.6 0.15 12.7 13.3 3.3 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 KxDL PF10241.9 KXS19262.1 - 1.5 9.1 16.0 0.4 11.0 2.8 2.9 1 1 2 3 3 3 0 Uncharacterized conserved protein MAD PF05557.13 KXS19262.1 - 1.7 6.9 31.4 0.26 9.6 21.9 2.1 1 1 1 2 2 2 0 Mitotic checkpoint protein AAA_32 PF13654.6 KXS19262.1 - 1.8 7.3 22.6 6.8 5.3 22.6 1.8 1 1 0 1 1 1 0 AAA domain bZIP_1 PF00170.21 KXS19262.1 - 1.9 8.7 24.9 14 5.8 8.0 4.8 2 1 1 3 3 3 0 bZIP transcription factor FAM76 PF16046.5 KXS19262.1 - 1.9 7.8 19.5 4.2 6.6 16.8 2.0 1 1 1 2 2 2 0 FAM76 protein FemAB PF02388.16 KXS19262.1 - 1.9 7.3 18.7 0.54 9.1 6.2 2.1 1 1 1 2 2 2 0 FemAB family Fmp27_WPPW PF10359.9 KXS19262.1 - 1.9 7.2 20.9 1.8 7.3 7.4 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain End3 PF12761.7 KXS19262.1 - 2 8.6 26.4 3.2 7.9 9.6 3.1 1 1 1 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 DUF5636 PF18686.1 KXS19262.1 - 2.1 8.5 9.1 0.42 10.8 1.8 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5636) Fez1 PF06818.15 KXS19262.1 - 2.1 8.8 27.0 6.7 7.1 10.6 2.1 1 1 0 1 1 1 0 Fez1 Mod_r PF07200.13 KXS19262.1 - 2.3 8.3 28.2 1.3 9.1 7.9 2.2 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF1759 PF03564.15 KXS19262.1 - 2.4 8.1 9.2 7.5 6.5 1.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1759) Sec2p PF06428.11 KXS19262.1 - 2.7 8.0 26.6 11 6.0 6.7 3.7 1 1 2 3 3 3 0 GDP/GTP exchange factor Sec2p DUF2937 PF11157.8 KXS19262.1 - 2.8 7.6 9.1 5.8 6.6 2.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) APG6_N PF17675.1 KXS19262.1 - 2.8 8.5 42.1 3.4 8.2 19.0 2.8 1 1 1 2 2 2 0 Apg6 coiled-coil region TSNAXIP1_N PF15739.5 KXS19262.1 - 2.9 8.3 22.8 2 8.8 5.2 3.1 1 1 1 2 2 2 0 Translin-associated factor X-interacting N-terminus TMF_DNA_bd PF12329.8 KXS19262.1 - 2.9 7.9 31.9 59 3.8 12.5 3.9 1 1 1 2 2 1 0 TATA element modulatory factor 1 DNA binding MCU PF04678.13 KXS19262.1 - 2.9 7.9 21.8 3.5 7.7 7.6 2.3 1 1 1 2 2 2 0 Mitochondrial calcium uniporter Dynamitin PF04912.14 KXS19262.1 - 3.1 7.0 27.4 1.9 7.7 11.3 2.1 1 1 1 2 2 2 0 Dynamitin ApoO PF09769.9 KXS19262.1 - 3.2 7.7 4.5 3.6 7.5 0.5 2.5 1 1 2 3 3 2 0 Apolipoprotein O PI3K_P85_iSH2 PF16454.5 KXS19262.1 - 3.3 7.3 26.7 0.59 9.7 12.5 2.7 1 1 2 3 3 3 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Prefoldin PF02996.17 KXS19262.1 - 3.6 7.5 24.6 0.22 11.4 3.1 4.1 1 1 2 4 4 4 0 Prefoldin subunit SKA1 PF07160.12 KXS19262.1 - 3.7 7.3 18.9 16 5.3 2.4 2.4 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 DUF2730 PF10805.8 KXS19262.1 - 3.8 7.7 15.8 1.1 9.4 4.0 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF2730) CAP_N PF01213.19 KXS19262.1 - 3.8 6.9 11.4 4.6 6.6 11.4 1.0 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal SOGA PF11365.8 KXS19262.1 - 3.8 8.7 25.2 7.6 7.7 9.6 2.7 1 1 2 3 3 3 0 Protein SOGA Ax_dynein_light PF10211.9 KXS19262.1 - 4.2 7.3 31.4 1.1 9.1 10.6 3.0 1 1 2 3 3 3 0 Axonemal dynein light chain DASH_Dam1 PF08653.10 KXS19262.1 - 4.4 7.2 9.3 3.2 7.6 1.0 3.9 3 2 1 4 4 3 0 DASH complex subunit Dam1 YlqD PF11068.8 KXS19262.1 - 4.6 7.6 28.7 2.5 8.5 10.7 2.4 1 1 2 3 3 3 0 YlqD protein CENP-H PF05837.12 KXS19262.1 - 4.8 7.6 29.3 7.6 7.0 11.9 2.6 1 1 0 2 2 2 0 Centromere protein H (CENP-H) DUF4140 PF13600.6 KXS19262.1 - 5.6 7.5 30.0 0.3 11.6 3.6 4.1 1 1 3 4 4 4 0 N-terminal domain of unknown function (DUF4140) AATF-Che1 PF13339.6 KXS19262.1 - 5.9 7.6 16.8 5.7 7.6 3.7 2.1 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor Sec34 PF04136.15 KXS19262.1 - 6.1 6.7 15.6 5.7 6.8 2.1 2.8 1 1 2 3 3 3 0 Sec34-like family Hormone_1 PF00103.20 KXS19262.1 - 6.3 6.5 13.3 0.75 9.5 1.4 2.9 1 1 2 3 3 3 0 Somatotropin hormone family DUF4446 PF14584.6 KXS19262.1 - 6.4 6.8 18.6 10 6.1 5.5 3.3 1 1 3 4 4 4 0 Protein of unknown function (DUF4446) FUSC PF04632.12 KXS19262.1 - 7.3 5.0 19.7 1.5 7.3 7.0 1.9 1 1 1 2 2 2 0 Fusaric acid resistance protein family XhlA PF10779.9 KXS19262.1 - 7.7 6.8 21.5 1.2 9.3 6.2 3.5 2 2 1 3 3 2 0 Haemolysin XhlA DASH_Spc19 PF08287.11 KXS19262.1 - 8.2 6.3 24.4 1.4 8.8 18.8 2.3 1 1 1 3 3 2 0 Spc19 GrpE PF01025.19 KXS19262.1 - 9.4 5.9 31.2 1.3 8.6 6.9 3.1 1 1 2 3 3 3 0 GrpE HalX PF08663.10 KXS19262.1 - 9.5 6.6 33.2 0.79 10.1 7.2 4.2 1 1 3 4 4 4 0 HalX domain WD40_alt PF14077.6 KXS19262.1 - 9.9 6.1 15.5 18 5.3 0.7 4.6 3 2 1 4 4 4 0 Alternative WD40 repeat motif YojJ PF10372.9 KXS19262.1 - 9.9 6.3 16.3 2.1 8.5 3.4 3.2 2 1 2 4 4 3 0 Bacterial membrane-spanning protein N-terminus Ndc80_HEC PF03801.13 KXS19265.1 - 2.3e-48 163.7 0.4 4.4e-48 162.8 0.4 1.4 1 0 0 1 1 1 1 HEC/Ndc80p family DUF5595 PF18077.1 KXS19265.1 - 1.7e-08 34.4 0.0 1.7e-08 34.4 0.0 3.7 2 1 1 3 3 3 1 Domain of unknown function (DUF5595) Rab5-bind PF09311.11 KXS19265.1 - 0.01 15.3 22.2 0.011 15.1 4.1 2.3 2 0 0 2 2 2 0 Rabaptin-like protein LMBR1 PF04791.16 KXS19265.1 - 0.24 10.3 7.5 0.51 9.2 0.7 2.1 2 0 0 2 2 2 0 LMBR1-like membrane protein ZnuA PF01297.17 KXS19265.1 - 0.81 9.0 3.4 0.45 9.9 0.4 2.1 2 0 0 2 2 2 0 Zinc-uptake complex component A periplasmic DUF4449 PF14613.6 KXS19265.1 - 2.8 8.0 11.7 0.066 13.3 3.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4449) Metallophos PF00149.28 KXS19266.1 - 6.7e-37 128.0 0.0 8.4e-37 127.7 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KXS19266.1 - 0.01 16.0 0.0 0.016 15.4 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain STPPase_N PF16891.5 KXS19266.1 - 0.011 16.2 0.3 0.021 15.3 0.3 1.4 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Glyco_hydro_65N PF03636.15 KXS19266.1 - 0.032 13.8 0.0 0.05 13.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain PALP PF00291.25 KXS19267.1 - 1.8e-63 214.7 0.0 3e-63 214.0 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.28 KXS19267.1 - 6.7e-15 55.3 0.0 2e-08 34.5 0.0 2.6 2 0 0 2 2 2 2 CBS domain GHMP_kinases_C PF08544.13 KXS19267.1 - 0.0016 18.8 1.8 0.046 14.1 0.0 3.0 4 0 0 4 4 4 1 GHMP kinases C terminal Sec23_trunk PF04811.15 KXS19267.1 - 0.15 11.6 0.0 0.29 10.7 0.0 1.4 1 0 0 1 1 1 0 Sec23/Sec24 trunk domain Pkinase PF00069.25 KXS19268.1 - 5.7e-74 248.8 0.0 8.2e-74 248.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS19268.1 - 3.5e-49 167.4 0.0 5.5e-49 166.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 KXS19268.1 - 2e-21 76.1 0.0 4.4e-21 75.0 0.0 1.6 1 0 0 1 1 1 1 P21-Rho-binding domain PH PF00169.29 KXS19268.1 - 4e-12 46.6 0.2 1.5e-11 44.7 0.2 1.9 2 0 0 2 2 2 1 PH domain Pkinase_fungal PF17667.1 KXS19268.1 - 1.1e-05 24.4 0.6 4.3e-05 22.5 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 KXS19268.1 - 1.3e-05 24.7 0.0 2.5e-05 23.8 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KXS19268.1 - 0.004 16.1 0.1 0.0072 15.3 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KXS19268.1 - 0.0073 16.3 0.1 0.034 14.1 0.1 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KXS19268.1 - 0.11 11.5 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Utp14 PF04615.13 KXS19268.1 - 5.3 5.5 8.6 8.8 4.8 8.6 1.3 1 1 0 1 1 1 0 Utp14 protein CRAL_TRIO PF00650.20 KXS19269.1 - 7.3e-40 136.3 0.2 1.2e-39 135.6 0.0 1.4 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KXS19269.1 - 9.9e-06 25.7 0.5 9.9e-06 25.7 0.5 2.0 2 1 0 2 2 2 1 CRAL/TRIO, N-terminal domain DUF1923 PF09083.10 KXS19271.1 - 0.18 11.5 0.0 0.33 10.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1923) Peptidase_C2 PF00648.21 KXS19272.1 - 6.8e-09 35.2 0.0 1.2e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease SEP PF08059.13 KXS19273.1 - 0.0025 18.3 0.0 0.0044 17.6 0.0 1.4 1 0 0 1 1 1 1 SEP domain YukD PF08817.10 KXS19273.1 - 0.0038 17.9 0.1 0.011 16.4 0.1 1.9 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukD HalX PF08663.10 KXS19273.1 - 0.41 11.0 3.0 0.78 10.1 1.6 2.2 1 1 1 2 2 2 0 HalX domain Pkinase PF00069.25 KXS19274.1 - 5.5e-46 157.1 0.0 8.6e-46 156.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS19274.1 - 7.4e-18 64.8 0.0 1.7e-17 63.6 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXS19274.1 - 3.5e-06 27.1 1.0 0.00033 20.7 0.3 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KXS19274.1 - 0.096 12.0 0.1 0.17 11.2 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3138 PF11336.8 KXS19275.1 - 3.7 6.0 8.1 5.5 5.5 8.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) bZIP_1 PF00170.21 KXS19276.1 - 3.3e-08 33.5 14.2 5e-08 32.9 14.2 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KXS19276.1 - 1.2e-06 28.5 16.6 1.7e-06 28.0 16.6 1.2 1 0 0 1 1 1 1 Basic region leucine zipper fn3 PF00041.21 KXS19280.1 - 5.2e-05 23.5 0.1 0.00012 22.3 0.1 1.7 1 0 0 1 1 1 1 Fibronectin type III domain ERM PF00769.19 KXS19280.1 - 0.002 18.0 31.2 0.0034 17.2 31.2 1.4 1 0 0 1 1 1 1 Ezrin/radixin/moesin family DUF812 PF05667.11 KXS19280.1 - 0.031 13.2 18.0 0.045 12.6 18.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Herpes_UL6 PF01763.16 KXS19281.1 - 0.00016 20.4 12.1 0.027 13.0 0.9 2.3 2 0 0 2 2 2 2 Herpesvirus UL6 like Ank_2 PF12796.7 KXS19281.1 - 0.01 16.4 0.0 0.034 14.7 0.0 1.8 1 1 1 2 2 2 0 Ankyrin repeats (3 copies) FtsQ PF03799.15 KXS19281.1 - 0.34 11.7 2.7 0.35 11.7 0.6 2.2 2 0 0 2 2 2 0 Cell division protein FtsQ HALZ PF02183.18 KXS19281.1 - 0.61 10.3 7.6 9.4 6.6 0.1 3.7 4 0 0 4 4 4 0 Homeobox associated leucine zipper Fez1 PF06818.15 KXS19281.1 - 1.7 9.0 40.8 0.77 10.2 22.5 2.4 2 0 0 2 2 2 0 Fez1 LPP PF04728.13 KXS19281.1 - 3.9 7.9 12.6 30 5.1 4.9 4.0 3 1 0 3 3 3 0 Lipoprotein leucine-zipper Filament PF00038.21 KXS19281.1 - 5.6 6.5 37.7 0.54 9.8 5.1 3.5 3 1 1 4 4 4 0 Intermediate filament protein Spc7 PF08317.11 KXS19281.1 - 5.7 5.7 35.5 2.3 7.0 19.8 2.6 2 1 0 2 2 2 0 Spc7 kinetochore protein Herpes_gE PF02480.16 KXS19282.1 - 0.012 14.4 0.0 0.022 13.5 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E PTP_tm PF18861.1 KXS19282.1 - 0.081 12.9 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J DUF4366 PF14283.6 KXS19282.1 - 0.084 12.9 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Gram_pos_anchor PF00746.21 KXS19282.1 - 0.1 12.6 0.7 0.35 10.8 0.7 2.0 1 0 0 1 1 1 0 LPXTG cell wall anchor motif Podoplanin PF05808.11 KXS19282.1 - 0.16 12.1 2.8 0.65 10.1 2.8 2.0 1 1 0 1 1 1 0 Podoplanin Pkinase PF00069.25 KXS19284.1 - 4.4e-66 222.9 0.0 6.5e-66 222.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS19284.1 - 5e-36 124.3 0.0 6.6e-36 123.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXS19284.1 - 2e-05 23.6 0.0 3.3e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KXS19284.1 - 0.001 19.0 1.1 0.016 15.1 0.2 2.4 2 1 1 3 3 3 1 Phosphotransferase enzyme family RIO1 PF01163.22 KXS19284.1 - 0.0012 18.4 0.0 0.0019 17.9 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 KXS19284.1 - 0.0096 15.3 0.0 0.013 14.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KXS19284.1 - 0.01 15.2 0.0 0.016 14.5 0.0 1.5 1 1 0 1 1 1 0 Kinase-like bZIP_1 PF00170.21 KXS19285.1 - 1.7e-06 28.0 7.0 1.7e-06 28.0 7.0 2.1 2 1 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 KXS19285.1 - 9.9e-06 25.5 8.7 9.9e-06 25.5 8.7 1.9 2 0 0 2 2 2 1 Basic region leucine zipper DUF812 PF05667.11 KXS19285.1 - 0.00022 20.3 0.5 0.00024 20.2 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) bZIP_Maf PF03131.17 KXS19285.1 - 0.0045 17.5 4.7 0.01 16.4 4.7 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor SIKE PF05769.11 KXS19285.1 - 0.0054 16.7 1.0 0.011 15.7 1.0 1.4 1 0 0 1 1 1 1 SIKE family DUF4726 PF15855.5 KXS19285.1 - 0.26 11.5 1.6 3.6 7.8 0.7 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4726) HAUS-augmin3 PF14932.6 KXS19285.1 - 0.31 10.6 4.2 0.49 9.9 4.2 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 SURF1 PF02104.15 KXS19286.1 - 3e-30 105.8 0.0 4.1e-30 105.3 0.0 1.2 1 0 0 1 1 1 1 SURF1 family Ank_3 PF13606.6 KXS19287.1 - 0.0003 21.0 0.1 0.091 13.4 0.0 3.8 4 0 0 4 4 4 1 Ankyrin repeat DUF3450 PF11932.8 KXS19287.1 - 0.025 13.9 7.1 0.042 13.1 7.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Ank_2 PF12796.7 KXS19287.1 - 0.029 14.9 0.0 1.1 9.9 0.0 2.8 2 1 0 2 2 2 0 Ankyrin repeats (3 copies) TSC22 PF01166.18 KXS19287.1 - 0.033 14.5 0.7 0.18 12.1 0.4 2.3 1 1 1 2 2 2 0 TSC-22/dip/bun family Ank_4 PF13637.6 KXS19287.1 - 0.2 12.3 0.1 55 4.5 0.0 3.9 5 0 0 5 5 5 0 Ankyrin repeats (many copies) Gastrin PF00918.17 KXS19287.1 - 3.2 8.7 5.7 1.4 9.9 2.6 1.9 2 0 0 2 2 2 0 Gastrin/cholecystokinin family ATG16 PF08614.11 KXS19287.1 - 4.5 7.5 17.6 12 6.1 17.6 1.6 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Pkinase PF00069.25 KXS19289.1 - 9.4e-64 215.3 0.0 1.1e-63 215.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS19289.1 - 1.5e-33 116.2 0.0 2.1e-33 115.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXS19289.1 - 0.00097 18.5 0.0 0.0016 17.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KXS19289.1 - 0.0044 16.4 0.0 0.007 15.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KXS19289.1 - 0.013 14.5 0.0 0.017 14.1 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 KXS19289.1 - 0.014 14.2 0.0 0.02 13.7 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Amidase PF01425.21 KXS19290.1 - 8.9e-71 239.2 0.0 1.2e-70 238.7 0.0 1.2 1 0 0 1 1 1 1 Amidase VIT PF08487.10 KXS19291.1 - 3.8e-33 114.0 0.1 9.8e-33 112.7 0.1 1.8 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.6 KXS19291.1 - 1.7e-23 83.3 0.0 3.4e-23 82.3 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KXS19291.1 - 1.6e-12 48.0 0.0 3.5e-12 46.9 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 KXS19291.1 - 2.5e-12 47.4 0.0 4.5e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT_2 PF13757.6 KXS19291.1 - 2e-11 43.6 0.0 3.9e-11 42.7 0.0 1.5 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain Synaptobrevin PF00957.21 KXS19291.1 - 3.7e-08 33.0 0.1 1.2e-07 31.4 0.2 1.7 2 0 0 2 2 2 1 Synaptobrevin DUF2076 PF09849.9 KXS19291.1 - 0.0095 16.0 1.0 0.0095 16.0 1.0 1.8 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2076) VWA_CoxE PF05762.14 KXS19291.1 - 0.012 15.0 0.0 0.028 13.8 0.0 1.5 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein CobT_C PF11775.8 KXS19291.1 - 0.049 13.3 0.0 0.23 11.1 0.0 2.0 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT VWA domain His_Phos_1 PF00300.22 KXS19292.1 - 4.9e-48 163.4 0.3 7.6e-48 162.8 0.3 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) MFS_1 PF07690.16 KXS19293.1 - 9.9e-48 162.8 44.6 3.5e-32 111.7 18.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KXS19293.1 - 1e-07 31.2 13.2 0.00029 19.8 4.6 2.8 2 1 0 2 2 2 2 MFS_1 like family MFS_2 PF13347.6 KXS19293.1 - 2.2e-06 26.5 15.0 0.001 17.7 1.7 2.5 2 1 0 2 2 2 2 MFS/sugar transport protein MFS_4 PF06779.14 KXS19293.1 - 2.9e-05 23.5 32.1 3.1e-05 23.5 9.3 2.5 3 0 0 3 3 3 2 Uncharacterised MFS-type transporter YbfB Sugar_tr PF00083.24 KXS19293.1 - 0.0045 15.9 21.8 0.0091 14.9 13.2 2.7 1 1 1 2 2 2 2 Sugar (and other) transporter MRP-S25 PF13741.6 KXS19294.1 - 2.4e-22 79.6 0.4 9.7e-22 77.7 0.4 1.8 1 1 0 1 1 1 1 Mitochondrial ribosomal protein S25 Usp PF00582.26 KXS19294.1 - 3.7 8.0 7.4 12 6.4 7.4 1.8 1 1 0 1 1 1 0 Universal stress protein family BTB PF00651.31 KXS19295.1 - 1e-15 57.9 0.0 3.6e-08 33.6 0.0 2.8 3 0 0 3 3 3 2 BTB/POZ domain Ank_2 PF12796.7 KXS19295.1 - 4e-07 30.5 0.0 1.3e-06 28.9 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXS19295.1 - 9.2e-05 22.9 0.0 0.00035 21.1 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXS19295.1 - 0.00033 20.9 0.0 0.0029 17.9 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXS19295.1 - 0.00079 19.7 0.0 0.057 14.0 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 KXS19295.1 - 0.0076 16.7 0.0 0.028 14.8 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeat F-box-like PF12937.7 KXS19296.1 - 3.8e-05 23.5 0.1 7.8e-05 22.5 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXS19296.1 - 0.00047 20.0 0.1 0.0011 18.8 0.1 1.5 1 0 0 1 1 1 1 F-box domain TPT PF03151.16 KXS19297.1 - 2.8e-13 49.9 7.7 9.9e-07 28.4 1.6 3.2 3 0 0 3 3 3 2 Triose-phosphate Transporter family EamA PF00892.20 KXS19297.1 - 1.3e-07 31.8 20.3 1.1e-06 28.9 5.7 3.1 4 0 0 4 4 4 2 EamA-like transporter family UAA PF08449.11 KXS19297.1 - 3.9e-06 26.3 0.4 3.9e-06 26.3 0.4 2.2 2 0 0 2 2 2 1 UAA transporter family PUNUT PF16913.5 KXS19297.1 - 0.00038 19.8 8.8 0.0076 15.5 0.3 2.3 2 0 0 2 2 2 2 Purine nucleobase transmembrane transport Nuc_sug_transp PF04142.15 KXS19297.1 - 0.0032 16.7 0.2 0.0032 16.7 0.2 2.1 2 0 0 2 2 2 1 Nucleotide-sugar transporter EmrE PF13536.6 KXS19297.1 - 0.039 13.5 4.8 0.11 12.0 4.8 1.8 1 1 0 1 1 1 0 Putative multidrug resistance efflux transporter DUF3742 PF12553.8 KXS19297.1 - 0.58 10.3 0.1 0.58 10.3 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3742) VIT PF08487.10 KXS19298.1 - 1.4e-35 121.9 0.1 2.4e-35 121.1 0.1 1.4 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.6 KXS19298.1 - 1.3e-25 90.1 0.0 2.4e-25 89.3 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 KXS19298.1 - 1.2e-15 58.3 0.0 2e-15 57.5 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KXS19298.1 - 2e-13 50.9 0.0 4e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT_2 PF13757.6 KXS19298.1 - 8.7e-12 44.8 0.0 1.7e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_CoxE PF05762.14 KXS19298.1 - 0.00045 19.7 0.0 0.00097 18.6 0.0 1.4 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein CobT_C PF11775.8 KXS19298.1 - 0.093 12.4 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT VWA domain DUF2201 PF09967.9 KXS19298.1 - 0.11 12.6 0.0 0.41 10.8 0.0 2.0 1 1 0 1 1 1 0 VWA-like domain (DUF2201) ELO PF01151.18 KXS19299.1 - 6.9e-57 192.8 22.7 8.4e-57 192.5 22.7 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family LapA_dom PF06305.11 KXS19299.1 - 0.0061 16.4 0.5 1.2 9.0 0.0 3.1 3 0 0 3 3 3 2 Lipopolysaccharide assembly protein A domain DivIC PF04977.15 KXS19300.1 - 0.023 14.5 1.3 0.033 14.0 0.5 1.6 2 0 0 2 2 2 0 Septum formation initiator Ish1 PF10281.9 KXS19300.1 - 0.026 14.8 0.5 0.064 13.6 0.1 1.8 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein BRI3BP PF14965.6 KXS19300.1 - 0.057 12.9 0.0 0.061 12.8 0.0 1.2 1 0 0 1 1 1 0 Negative regulator of p53/TP53 FlaC_arch PF05377.11 KXS19300.1 - 0.1 13.0 1.9 0.25 11.7 0.2 2.0 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF4635 PF15466.6 KXS19300.1 - 0.12 11.9 0.2 0.17 11.4 0.2 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4635) SBP_bac_3 PF00497.20 KXS19301.1 - 6e-32 110.9 0.1 2.3e-31 109.0 0.1 1.7 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.9 KXS19301.1 - 0.044 14.0 0.0 0.08 13.1 0.0 1.6 1 1 0 1 1 1 0 Ligated ion channel L-glutamate- and glycine-binding site DUF2315 PF10231.9 KXS19303.1 - 9.9e-14 51.5 0.0 1.4e-13 51.0 0.0 1.2 1 0 0 1 1 1 1 Apoptogenic protein 1 Hox9_act PF04617.13 KXS19303.1 - 0.63 10.8 5.0 0.76 10.5 5.0 1.2 1 0 0 1 1 1 0 Hox9 activation region GDPD PF03009.17 KXS19305.1 - 9.4e-21 74.7 0.0 1.7e-19 70.5 0.0 2.0 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.6 KXS19305.1 - 0.04 14.4 0.0 0.1 13.1 0.0 1.7 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family ABC_membrane_2 PF06472.15 KXS19306.1 - 3.6e-100 334.8 3.6 5.3e-100 334.3 3.6 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 KXS19306.1 - 4.1e-18 66.2 0.0 1.3e-17 64.6 0.0 1.8 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 KXS19306.1 - 9.9e-06 25.6 0.1 3.2e-05 23.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KXS19306.1 - 0.0011 19.5 4.8 0.0068 16.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 KXS19306.1 - 0.0017 17.8 0.1 0.055 12.9 0.1 2.3 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KXS19306.1 - 0.0095 15.7 0.1 0.024 14.4 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_27 PF13514.6 KXS19306.1 - 0.014 15.0 1.1 0.042 13.4 0.0 2.2 3 0 0 3 3 3 0 AAA domain FAM184 PF15665.5 KXS19306.1 - 0.046 13.5 2.7 1.1 9.0 3.1 2.2 2 0 0 2 2 2 0 Family with sequence similarity 184, A and B DUF4258 PF14076.6 KXS19306.1 - 0.18 12.2 0.0 0.43 11.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4258) Pkinase PF00069.25 KXS19307.1 - 8.8e-28 97.4 0.0 1.3e-27 96.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS19307.1 - 3.6e-11 42.9 0.0 5.3e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KXS19307.1 - 0.0025 17.2 0.0 0.0042 16.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KXS19307.1 - 0.011 15.4 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 KXS19307.1 - 0.013 15.4 0.7 0.023 14.6 0.7 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KXS19307.1 - 0.049 12.6 0.0 0.071 12.0 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 KXS19307.1 - 0.086 12.1 0.1 0.17 11.1 0.1 1.5 1 1 0 1 1 1 0 Kinase-like p25-alpha PF05517.12 KXS19308.1 - 4.3e-15 56.2 1.4 9.6e-15 55.1 1.1 1.7 2 0 0 2 2 2 1 p25-alpha DCX PF03607.17 KXS19308.1 - 0.069 13.3 0.0 0.17 12.0 0.0 1.8 1 1 0 1 1 1 0 Doublecortin DUF2387 PF09526.10 KXS19309.1 - 0.0098 16.0 1.5 0.018 15.2 0.6 1.9 2 0 0 2 2 2 1 Probable metal-binding protein (DUF2387) 4HBT_2 PF13279.6 KXS19310.1 - 1e-12 48.6 0.0 1.5e-12 48.1 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily Pol_alpha_B_N PF08418.10 KXS19311.1 - 0.58 10.1 5.7 1.3 9.0 5.7 1.5 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal DUF1387 PF07139.11 KXS19311.1 - 1.3 8.7 7.4 0.54 9.9 3.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1387) JmjC PF02373.22 KXS19312.1 - 1.5e-07 31.8 0.0 1.8e-07 31.6 0.0 1.1 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 KXS19312.1 - 0.15 11.8 0.0 0.15 11.8 0.0 1.0 1 0 0 1 1 1 0 Cupin-like domain DEAD PF00270.29 KXS19313.1 - 4.1e-19 69.0 0.0 9.5e-19 67.8 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXS19313.1 - 1.4e-16 60.8 0.0 3.6e-16 59.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXS19313.1 - 0.00059 19.9 0.0 0.0022 18.0 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit tRNA_Me_trans PF03054.16 KXS19314.1 - 1.2e-116 389.4 0.0 1.3e-116 389.2 0.0 1.0 1 0 0 1 1 1 1 tRNA methyl transferase NAD_synthase PF02540.17 KXS19314.1 - 9.8e-06 24.8 0.0 0.0035 16.5 0.0 2.2 2 0 0 2 2 2 2 NAD synthase ThiI PF02568.14 KXS19314.1 - 3.9e-05 23.3 0.0 8.4e-05 22.2 0.0 1.6 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) QueC PF06508.13 KXS19314.1 - 0.0017 17.9 0.0 0.004 16.7 0.0 1.6 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC SRCR PF00530.18 KXS19314.1 - 0.063 13.8 0.1 0.13 12.8 0.1 1.5 1 0 0 1 1 1 0 Scavenger receptor cysteine-rich domain Asn_synthase PF00733.21 KXS19314.1 - 0.11 12.2 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Asparagine synthase PIG-L PF02585.17 KXS19314.1 - 0.15 12.7 0.0 0.27 11.8 0.0 1.4 1 0 0 1 1 1 0 GlcNAc-PI de-N-acetylase Rax2 PF12768.7 KXS19315.1 - 0.006 16.1 0.0 0.0099 15.3 0.0 1.4 1 0 0 1 1 1 1 Cortical protein marker for cell polarity Podoplanin PF05808.11 KXS19315.1 - 0.15 12.1 7.7 0.65 10.1 7.7 2.0 1 1 0 1 1 1 0 Podoplanin SKG6 PF08693.10 KXS19315.1 - 0.17 11.3 5.1 0.36 10.3 5.1 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Stevor PF17410.2 KXS19315.1 - 0.81 9.2 3.5 2.2 7.7 3.5 1.8 1 1 0 1 1 1 0 Subtelomeric Variable Open Reading frame VIT1 PF01988.19 KXS19316.1 - 2.9e-53 180.9 3.0 2.9e-53 180.9 3.0 1.9 2 1 0 2 2 2 1 VIT family Chitin_bind_1 PF00187.19 KXS19316.1 - 1.1e-08 35.4 20.3 1.1e-08 35.4 20.3 2.8 3 1 0 3 3 3 1 Chitin recognition protein LRR_8 PF13855.6 KXS19316.1 - 0.00062 19.5 0.4 0.0012 18.5 0.4 1.5 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 KXS19316.1 - 0.0023 18.3 3.7 0.0057 17.1 3.7 1.7 1 0 0 1 1 1 1 Leucine Rich repeats (2 copies) DUF2613 PF11021.8 KXS19316.1 - 0.098 12.8 0.1 0.098 12.8 0.1 4.4 4 0 0 4 4 4 0 Protein of unknown function (DUF2613) DUF4741 PF15897.5 KXS19317.1 - 0.093 12.5 0.2 0.15 11.9 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4741) zinc_ribbon_16 PF17034.5 KXS19318.1 - 5.9e-21 75.0 7.0 7.6e-13 48.8 2.3 2.6 2 0 0 2 2 2 2 Zinc-ribbon like family Sod_Fe_C PF02777.18 KXS19319.1 - 1.3e-37 128.0 1.1 2.2e-37 127.3 0.6 1.6 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 KXS19319.1 - 1.5e-23 83.1 0.2 3.1e-23 82.1 0.2 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Rb_C PF08934.10 KXS19319.1 - 0.034 14.0 0.0 0.047 13.5 0.0 1.3 1 0 0 1 1 1 0 Rb C-terminal domain LRR_6 PF13516.6 KXS19320.1 - 1.7e-16 58.8 8.8 0.051 13.6 0.0 8.0 8 0 0 8 8 8 6 Leucine Rich repeat LRR_4 PF12799.7 KXS19320.1 - 3.2e-05 24.2 0.0 2.2 8.8 0.1 4.8 3 3 2 5 5 5 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KXS19320.1 - 0.025 15.1 0.1 47 5.1 0.1 5.0 7 0 0 7 7 7 0 Leucine Rich Repeat LRR_8 PF13855.6 KXS19320.1 - 0.12 12.2 1.6 23 4.8 1.7 3.9 3 2 1 4 4 4 0 Leucine rich repeat SRP19 PF01922.17 KXS19321.1 - 3.4e-13 50.3 0.0 3.4e-07 31.1 0.0 2.3 2 0 0 2 2 2 2 SRP19 protein SIR2 PF02146.17 KXS19322.1 - 1.6e-38 132.4 0.4 9.2e-25 87.6 0.2 2.8 2 1 0 2 2 2 2 Sir2 family zf-ribbon_3 PF13248.6 KXS19322.1 - 9.6 5.8 6.3 5.5 6.5 0.1 2.6 3 0 0 3 3 3 0 zinc-ribbon domain Fasciclin PF02469.22 KXS19323.1 - 4.4e-11 43.1 1.1 1e-06 29.0 0.1 3.1 2 2 0 2 2 2 2 Fasciclin domain FGGY_N PF00370.21 KXS19324.1 - 6.2e-69 232.3 0.0 8.6e-69 231.8 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 KXS19324.1 - 5.3e-66 222.1 0.4 7.9e-66 221.6 0.4 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain GCR PF02155.15 KXS19325.1 - 0.002 17.3 0.1 0.0024 17.0 0.1 1.2 1 0 0 1 1 1 1 Glucocorticoid receptor WD40 PF00400.32 KXS19326.1 - 9.4e-08 32.6 7.4 0.0053 17.6 0.2 4.5 4 0 0 4 4 4 2 WD domain, G-beta repeat adh_short PF00106.25 KXS19327.1 - 1.9e-06 27.5 0.0 6.6e-06 25.7 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase GST_N_3 PF13417.6 KXS19328.1 - 8.5e-08 32.5 0.0 4.3e-07 30.3 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KXS19328.1 - 1.9e-06 28.1 0.0 3e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain AMP-binding PF00501.28 KXS19329.1 - 2e-06 26.7 0.7 4.4e-05 22.3 0.7 2.7 1 1 0 1 1 1 1 AMP-binding enzyme Ribosomal_L16 PF00252.18 KXS19330.1 - 8.6e-33 113.2 0.1 2.4e-32 111.7 0.1 1.7 1 1 0 1 1 1 1 Ribosomal protein L16p/L10e DIMCO_N PF16844.5 KXS19330.1 - 0.11 12.9 1.5 0.22 11.9 1.5 1.5 1 0 0 1 1 1 0 Dinitrogenase iron-molybdenum cofactor, N-terminal Secretin_N_2 PF07655.13 KXS19330.1 - 0.26 11.8 9.8 0.52 10.9 9.8 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain Sporozoite_P67 PF05642.11 KXS19330.1 - 2.6 6.0 10.7 3.5 5.6 10.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen UQ_con PF00179.26 KXS19331.1 - 2.5e-35 121.2 0.0 3.3e-35 120.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KXS19331.1 - 0.0013 18.5 0.0 0.0019 17.9 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B TPT PF03151.16 KXS19332.1 - 6.7e-25 88.0 14.8 8.2e-25 87.7 14.8 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KXS19332.1 - 6.1e-10 39.4 23.2 1.4e-05 25.2 11.8 2.1 2 0 0 2 2 2 2 EamA-like transporter family DUF4079 PF13301.6 KXS19332.1 - 0.28 11.3 5.4 0.81 9.8 5.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF4079) tRNA-synt_2 PF00152.20 KXS19333.1 - 2.4e-77 260.1 0.2 3.1e-77 259.7 0.2 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KXS19333.1 - 2.6e-05 24.1 0.2 5.8e-05 23.0 0.2 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain ILEI PF15711.5 KXS19333.1 - 0.035 14.6 0.1 0.094 13.2 0.1 1.7 2 0 0 2 2 2 0 Interleukin-like EMT inducer HMG-CoA_red PF00368.18 KXS19334.1 - 2.9e-144 480.6 1.4 4.1e-144 480.1 1.4 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase Sterol-sensing PF12349.8 KXS19334.1 - 1.7e-15 57.2 6.6 6.9e-15 55.2 3.6 2.5 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation HPIH PF13323.6 KXS19334.1 - 7.3e-06 25.9 0.1 1.8e-05 24.6 0.1 1.7 1 0 0 1 1 1 1 N-terminal domain with HPIH motif Patched PF02460.18 KXS19334.1 - 1.3e-05 23.5 0.3 2.1e-05 22.9 0.3 1.2 1 0 0 1 1 1 1 Patched family PNP_UDP_1 PF01048.20 KXS19335.1 - 2.5e-22 79.3 0.0 3.2e-22 78.9 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Sterol-sensing PF12349.8 KXS19336.1 - 9.4e-47 158.7 8.9 1.7e-46 157.8 8.9 1.4 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 KXS19336.1 - 7.9e-24 83.8 11.5 1e-23 83.4 11.5 1.1 1 0 0 1 1 1 1 Patched family EF-hand_7 PF13499.6 KXS19337.1 - 1.3e-18 67.2 10.9 2e-12 47.4 3.0 2.9 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 KXS19337.1 - 7.1e-16 56.5 13.3 1.2e-06 27.6 1.8 4.6 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.6 KXS19337.1 - 2.5e-13 49.7 7.0 4.3e-05 23.3 0.3 4.0 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 KXS19337.1 - 2.5e-13 48.8 8.1 4.5e-07 29.3 1.4 3.4 4 0 0 4 4 4 2 EF-hand domain EF-hand_5 PF13202.6 KXS19337.1 - 3.4e-08 32.6 9.9 0.00075 18.9 2.3 2.7 3 0 0 3 3 3 2 EF hand EF-hand_11 PF08976.11 KXS19337.1 - 3.9e-08 34.1 0.1 1.2e-07 32.5 0.1 1.7 1 1 1 2 2 2 1 EF-hand domain UPF0154 PF03672.13 KXS19337.1 - 2e-05 24.5 0.0 0.21 11.6 0.0 2.5 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0154) SPARC_Ca_bdg PF10591.9 KXS19337.1 - 0.00075 19.8 0.6 0.03 14.6 0.1 2.1 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 KXS19337.1 - 0.0013 19.0 0.1 2.3 8.6 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain EFhand_Ca_insen PF08726.10 KXS19337.1 - 0.034 14.2 0.6 0.44 10.7 0.1 2.3 2 0 0 2 2 2 0 Ca2+ insensitive EF hand RNA_pol_Rpb4 PF03874.16 KXS19337.1 - 0.16 12.3 0.7 3.1 8.2 0.0 2.3 2 1 0 2 2 2 0 RNA polymerase Rpb4 RRM_1 PF00076.22 KXS19338.1 - 2.9e-32 110.3 0.0 7.5e-12 44.9 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KXS19338.1 - 0.0001 22.1 0.0 0.087 12.7 0.0 3.1 3 0 0 3 3 3 1 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 KXS19338.1 - 0.00043 20.2 0.0 4.9 7.2 0.0 3.6 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif DUF4123 PF13503.6 KXS19338.1 - 0.0029 18.0 0.0 0.25 11.8 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4123) RRM_5 PF13893.6 KXS19338.1 - 0.0061 16.2 0.0 0.12 12.0 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KXS19338.1 - 0.036 14.1 0.0 0.49 10.5 0.0 2.3 2 0 0 2 2 2 0 RNA binding motif An_peroxidase PF03098.15 KXS19340.1 - 7.3e-135 450.5 0.0 1.8e-134 449.3 0.0 1.6 1 1 0 1 1 1 1 Animal haem peroxidase NAD_binding_6 PF08030.12 KXS19340.1 - 1.4e-26 93.5 0.0 2.3e-26 92.8 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KXS19340.1 - 2.1e-15 56.7 1.1 4.2e-15 55.8 0.0 2.0 2 0 0 2 2 1 1 FAD-binding domain Ferric_reduct PF01794.19 KXS19340.1 - 1e-11 45.0 15.5 3.4e-11 43.4 14.2 2.2 2 0 0 2 2 2 1 Ferric reductase like transmembrane component EF-hand_7 PF13499.6 KXS19340.1 - 1.9e-09 37.8 0.5 2.5e-05 24.6 0.0 3.2 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KXS19340.1 - 3e-09 36.1 1.4 0.0019 18.0 0.0 3.3 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 KXS19340.1 - 2.9e-08 32.7 3.8 0.0014 18.1 0.1 3.7 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 KXS19340.1 - 0.00015 21.6 0.7 0.23 11.4 0.2 2.9 3 0 0 3 3 3 2 EF-hand domain pair NAD_binding_1 PF00175.21 KXS19340.1 - 0.0018 18.9 0.0 0.013 16.1 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain EF-hand_5 PF13202.6 KXS19340.1 - 0.0022 17.4 0.3 3.1 7.4 0.0 2.8 2 0 0 2 2 2 2 EF hand APOBEC_C PF05240.14 KXS19340.1 - 0.15 12.1 0.1 17 5.5 0.0 2.8 2 0 0 2 2 2 0 APOBEC-like C-terminal domain HemY_N PF07219.13 KXS19340.1 - 1.1 9.5 3.3 0.51 10.6 0.3 2.1 2 0 0 2 2 2 0 HemY protein N-terminus DuoxA PF10204.9 KXS19341.1 - 6.1e-43 146.8 5.1 7.7e-43 146.5 5.1 1.0 1 0 0 1 1 1 1 Dual oxidase maturation factor OST3_OST6 PF04756.13 KXS19341.1 - 0.048 13.0 0.0 0.048 13.0 0.0 1.5 2 0 0 2 2 2 0 OST3 / OST6 family, transporter family NUSAP PF16006.5 KXS19342.1 - 8.4e-12 45.5 0.2 1.1e-06 28.6 0.1 2.5 2 0 0 2 2 2 2 Nucleolar and spindle-associated protein SAP PF02037.27 KXS19342.1 - 0.00091 18.9 0.0 0.0018 18.0 0.0 1.5 1 0 0 1 1 1 1 SAP domain WD40 PF00400.32 KXS19343.1 - 4.9e-35 119.0 11.0 1.5e-05 25.6 0.0 9.5 9 0 0 9 9 9 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXS19343.1 - 1.3e-12 47.9 2.9 2.6e-05 24.4 0.0 5.7 2 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KXS19343.1 - 4e-09 35.7 3.3 0.0053 15.5 0.1 4.3 3 1 1 4 4 4 3 Nucleoporin Nup120/160 EF-hand_7 PF13499.6 KXS19343.1 - 0.00012 22.4 0.4 0.00046 20.6 0.4 2.1 1 0 0 1 1 1 1 EF-hand domain pair Ge1_WD40 PF16529.5 KXS19343.1 - 0.00021 20.4 0.2 1.8 7.5 0.0 3.7 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF5046 PF16465.5 KXS19343.1 - 0.00029 20.4 0.0 0.00056 19.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5046) Nucleoporin_N PF08801.11 KXS19343.1 - 0.00044 19.1 0.2 0.16 10.7 0.0 3.6 3 1 1 4 4 4 1 Nup133 N terminal like EF-hand_1 PF00036.32 KXS19343.1 - 0.0006 19.2 0.1 0.0018 17.7 0.1 1.9 1 0 0 1 1 1 1 EF hand eIF2A PF08662.11 KXS19343.1 - 0.0011 18.9 0.1 2.1 8.2 0.0 2.9 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A EF-hand_8 PF13833.6 KXS19343.1 - 0.0015 18.4 0.3 0.0044 16.8 0.3 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 KXS19343.1 - 0.0044 16.5 0.0 0.012 15.0 0.0 1.8 1 0 0 1 1 1 1 EF hand PALB2_WD40 PF16756.5 KXS19343.1 - 0.0073 15.3 0.4 0.22 10.4 0.2 2.6 1 1 0 1 1 1 1 Partner and localizer of BRCA2 WD40 domain EF-hand_6 PF13405.6 KXS19343.1 - 0.011 15.6 0.0 0.044 13.7 0.0 2.1 1 0 0 1 1 1 0 EF-hand domain Utp8 PF10395.9 KXS19343.1 - 0.078 11.5 0.0 9.1 4.6 0.0 2.9 2 1 0 2 2 2 0 Utp8 family TPR_2 PF07719.17 KXS19344.1 - 1.8e-10 40.1 0.0 2.7e-06 27.1 0.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 KXS19344.1 - 6e-08 32.2 0.2 1.9e-05 24.3 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 KXS19344.1 - 1.2e-07 32.2 0.2 1.7e-07 31.6 0.2 1.2 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 KXS19344.1 - 2.7e-07 30.3 0.2 0.0067 16.5 0.0 2.5 3 0 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KXS19344.1 - 7.2e-06 26.1 0.0 9.2e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 KXS19344.1 - 3e-05 24.5 0.1 0.068 14.0 0.0 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 KXS19344.1 - 6.6e-05 22.7 0.0 0.13 12.4 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 KXS19344.1 - 9.4e-05 22.5 0.1 0.01 16.2 0.0 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 KXS19344.1 - 0.0035 17.9 0.0 0.0056 17.3 0.0 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.6 KXS19344.1 - 0.0046 16.6 1.8 0.11 12.2 0.5 2.2 2 0 0 2 2 2 1 TPR repeat TPR_12 PF13424.6 KXS19344.1 - 0.0047 17.2 0.1 0.041 14.2 0.1 2.1 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_20 PF14561.6 KXS19344.1 - 0.055 13.8 0.1 0.077 13.3 0.1 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_3 PF07720.12 KXS19344.1 - 0.11 12.6 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.6 KXS19344.1 - 0.11 13.2 0.1 16 6.4 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat BTAD PF03704.17 KXS19344.1 - 0.14 12.6 0.0 0.15 12.5 0.0 1.1 1 0 0 1 1 1 0 Bacterial transcriptional activator domain DUF3591 PF12157.8 KXS19345.1 - 2.2e-135 451.8 0.0 2.7e-135 451.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) TFIIF_beta PF02270.15 KXS19345.1 - 0.014 15.5 0.0 0.031 14.4 0.0 1.5 1 0 0 1 1 1 0 TFIIF, beta subunit HTH domain PX PF00787.24 KXS19346.1 - 5.2e-26 90.9 0.1 6.1e-26 90.6 0.1 1.1 1 0 0 1 1 1 1 PX domain ALG11_N PF15924.5 KXS19347.1 - 3.3e-83 278.8 0.2 4.5e-83 278.4 0.2 1.2 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 KXS19347.1 - 8.1e-21 74.3 0.0 2.3e-20 72.8 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KXS19347.1 - 2.3e-08 34.5 0.0 4.2e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KXS19347.1 - 1.3e-05 25.3 0.0 4.2e-05 23.6 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Pkinase PF00069.25 KXS19348.1 - 2.5e-51 174.6 0.0 5e-50 170.3 0.0 2.7 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS19348.1 - 1.3e-31 109.9 0.0 7.3e-31 107.4 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXS19348.1 - 7.5e-05 22.2 0.0 0.046 13.0 0.0 2.4 2 0 0 2 2 2 2 Kinase-like E3_UbLigase_R4 PF13764.6 KXS19348.1 - 0.05 11.8 0.7 0.43 8.7 0.0 2.0 2 0 0 2 2 2 0 E3 ubiquitin-protein ligase UBR4 Pkinase_fungal PF17667.1 KXS19348.1 - 0.079 11.7 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase NopRA1 PF16201.5 KXS19348.1 - 0.085 12.4 0.0 0.33 10.5 0.0 2.2 1 1 0 1 1 1 0 Nucleolar pre-ribosomal-associated protein 1 Coatomer_WDAD PF04053.14 KXS19349.1 - 1.9e-06 27.2 13.2 0.00042 19.5 1.6 3.8 4 0 0 4 4 4 3 Coatomer WD associated region TPR_14 PF13428.6 KXS19349.1 - 1.7e-05 25.2 9.2 3 8.9 0.2 7.7 7 1 1 8 8 6 1 Tetratricopeptide repeat Clathrin PF00637.20 KXS19349.1 - 8e-05 22.5 10.9 4.9 7.0 0.0 6.3 5 1 2 7 7 7 3 Region in Clathrin and VPS TPR_2 PF07719.17 KXS19349.1 - 0.00029 20.7 16.9 0.15 12.3 1.3 6.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 KXS19349.1 - 0.0034 17.3 14.4 12 6.2 0.7 6.8 6 1 1 7 7 7 1 Tetratricopeptide repeat PPR PF01535.20 KXS19349.1 - 0.006 16.7 0.8 1.6 9.2 0.0 4.9 4 1 0 4 4 4 1 PPR repeat TPR_1 PF00515.28 KXS19349.1 - 0.012 15.4 14.3 0.065 13.1 1.2 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_19 PF14559.6 KXS19349.1 - 0.036 14.6 9.8 3.4 8.2 0.9 6.2 6 2 2 8 8 6 0 Tetratricopeptide repeat PPR_2 PF13041.6 KXS19349.1 - 0.053 13.7 0.1 6.9 6.9 0.1 3.2 3 0 0 3 3 3 0 PPR repeat family PPR_1 PF12854.7 KXS19349.1 - 0.065 13.0 0.0 0.24 11.1 0.0 2.0 1 0 0 1 1 1 0 PPR repeat TPR_8 PF13181.6 KXS19349.1 - 0.11 12.8 18.8 1.5 9.2 0.6 7.1 7 0 0 7 7 7 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KXS19349.1 - 0.29 11.4 13.4 0.31 11.3 3.9 4.7 5 0 0 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 KXS19349.1 - 7.1 7.4 13.2 1.3 9.7 1.0 4.7 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 KXS19349.1 - 7.8 7.4 13.3 9.6 7.1 1.7 5.9 5 1 1 6 6 5 0 Tetratricopeptide repeat HetR_C PF18460.1 KXS19350.1 - 0.05 13.5 0.4 0.087 12.8 0.4 1.4 1 0 0 1 1 1 0 Heterocyst differentiation regulator C-terminal Hood domain DUF5093 PF17011.5 KXS19350.1 - 0.094 13.0 1.7 0.12 12.6 1.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5093) DUF2407_C PF13373.6 KXS19350.1 - 0.1 12.8 0.5 0.12 12.6 0.5 1.2 1 0 0 1 1 1 0 DUF2407 C-terminal domain Dimer_Tnp_hAT PF05699.14 KXS19352.1 - 4.4e-18 64.9 0.0 4.7e-18 64.7 0.0 1.0 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Rotamase PF00639.21 KXS19353.1 - 1.1e-24 87.1 0.0 1.5e-24 86.8 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 KXS19353.1 - 6.4e-24 84.7 0.0 8.9e-24 84.3 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.26 KXS19353.1 - 4.2e-07 29.9 5.0 4.2e-07 29.9 5.0 1.6 2 0 0 2 2 2 1 WW domain Rotamase_2 PF13145.6 KXS19353.1 - 2e-06 28.6 0.0 2.6e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain POT1PC PF16686.5 KXS19354.1 - 2.6e-15 56.6 0.0 4.1e-10 39.7 0.0 3.0 2 1 1 3 3 3 2 ssDNA-binding domain of telomere protection protein POT1 PF02765.17 KXS19354.1 - 1.8e-12 47.3 0.5 6.1e-12 45.6 0.1 1.9 2 1 0 2 2 2 1 Telomeric single stranded DNA binding POT1/CDC13 TBCC_N PF16752.5 KXS19354.1 - 0.0014 19.1 0.0 3.3 8.2 0.0 3.1 2 1 1 3 3 3 2 Tubulin-specific chaperone C N-terminal domain Rep_fac-A_C PF08646.10 KXS19355.1 - 0.0025 17.6 0.1 0.0031 17.3 0.1 1.3 1 1 0 1 1 1 1 Replication factor-A C terminal domain CDC24_OB3 PF17244.2 KXS19355.1 - 0.069 12.8 0.1 0.086 12.5 0.1 1.1 1 0 0 1 1 1 0 Cell division control protein 24, OB domain 3 Nucleoporin_N PF08801.11 KXS19356.1 - 2e-58 198.2 0.0 2.9e-58 197.6 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 KXS19356.1 - 4.2e-21 75.3 1.4 7.1e-21 74.6 1.4 1.3 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal FAD_binding_1 PF00667.20 KXS19357.1 - 3.4e-42 144.5 0.0 5.9e-42 143.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KXS19357.1 - 6.3e-30 104.3 0.0 1.1e-29 103.4 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 KXS19357.1 - 5.9e-10 39.8 0.0 1.5e-09 38.5 0.0 1.6 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_3 PF12641.7 KXS19357.1 - 0.0041 16.8 0.0 0.011 15.5 0.0 1.7 2 0 0 2 2 2 1 Flavodoxin domain Flavodoxin_5 PF12724.7 KXS19357.1 - 0.01 16.1 0.0 2.9 8.1 0.0 2.9 2 1 1 3 3 3 0 Flavodoxin domain TRM PF02005.16 KXS19358.1 - 2.1e-130 435.3 0.0 2.5e-130 435.0 0.0 1.0 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.16 KXS19358.1 - 8.6e-09 35.4 0.0 1.4e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_15 PF09445.10 KXS19358.1 - 0.023 14.3 0.0 0.04 13.5 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase PrmA PF06325.13 KXS19358.1 - 0.028 13.8 0.0 0.043 13.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 KXS19358.1 - 0.12 13.1 0.0 0.26 12.0 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.15 KXS19358.1 - 0.16 11.6 0.0 0.31 10.7 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Mago_nashi PF02792.14 KXS19359.1 - 0.046 13.8 2.0 0.13 12.4 2.0 1.8 1 0 0 1 1 1 0 Mago nashi protein PDEase_I_N PF08499.12 KXS19359.1 - 0.63 9.9 5.1 1.2 9.0 0.2 3.0 2 1 1 3 3 3 0 3'5'-cyclic nucleotide phosphodiesterase N-terminal Peptidase_C48 PF02902.19 KXS19360.1 - 1.3e-46 159.1 0.5 1.5e-46 158.9 0.5 1.0 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Polysacc_deac_1 PF01522.21 KXS19361.1 - 1.4e-22 79.9 0.0 2.3e-22 79.2 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 KXS19361.1 - 0.043 13.5 0.0 0.067 12.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) DUF5419 PF17441.2 KXS19361.1 - 0.21 11.7 4.3 11 6.2 0.2 3.0 3 0 0 3 3 3 0 Family of unknown function (DUF5419) CAP_N PF01213.19 KXS19361.1 - 1.3 8.5 13.4 4 6.8 1.7 2.2 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Glyco_hydro_79C PF16862.5 KXS19361.1 - 2.6 9.0 5.4 2.4 9.1 0.4 2.7 2 1 0 2 2 2 0 Glycosyl hydrolase family 79 C-terminal beta domain Mito_fiss_reg PF05308.11 KXS19361.1 - 4.3 7.3 4.3 16 5.5 0.4 2.1 2 0 0 2 2 2 0 Mitochondrial fission regulator DUF4139 PF13598.6 KXS19362.1 - 1.8e-50 171.5 0.1 4.1e-47 160.6 0.2 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4139) DUF4140 PF13600.6 KXS19362.1 - 5.6e-12 45.9 1.4 5e-11 42.9 0.2 2.6 2 0 0 2 2 2 1 N-terminal domain of unknown function (DUF4140) UPF0160 PF03690.13 KXS19362.1 - 0.032 13.9 0.1 0.053 13.2 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0160) adh_short PF00106.25 KXS19363.1 - 4.7e-50 169.8 3.0 6e-50 169.4 3.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXS19363.1 - 1.4e-47 162.3 4.4 1.7e-47 162.0 4.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXS19363.1 - 2.5e-12 47.1 1.3 3.7e-12 46.5 1.2 1.3 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KXS19363.1 - 4e-05 23.2 0.9 0.00027 20.5 0.9 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family SH3_9 PF14604.6 KXS19364.1 - 0.0045 16.8 0.0 0.0071 16.2 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXS19364.1 - 0.007 16.0 0.4 0.012 15.2 0.1 1.5 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 KXS19365.1 - 5.8e-08 32.5 0.5 8.5e-06 25.5 0.0 2.4 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 KXS19365.1 - 0.032 13.8 0.0 0.064 12.9 0.0 1.5 1 0 0 1 1 1 0 SH3 domain Apt1 PF10351.9 KXS19365.1 - 0.2 10.5 10.9 0.27 10.0 10.9 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 KXS19365.1 - 0.31 9.5 13.2 0.42 9.1 13.2 1.1 1 0 0 1 1 1 0 Macoilin family Velvet PF11754.8 KXS19365.1 - 0.97 9.3 17.1 6.1 6.7 17.1 2.0 1 1 0 1 1 1 0 Velvet factor Podoplanin PF05808.11 KXS19365.1 - 1.5 8.9 15.4 3.8 7.6 15.4 1.6 1 1 0 1 1 1 0 Podoplanin DUF4614 PF15391.6 KXS19365.1 - 4.3 7.3 19.4 7.7 6.5 19.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) PAP1 PF08601.10 KXS19365.1 - 8.4 6.0 19.7 19 4.8 19.7 1.6 1 0 0 1 1 1 0 Transcription factor PAP1 TMEM154 PF15102.6 KXS19365.1 - 9.1 6.2 9.4 63 3.5 9.4 2.0 1 1 0 1 1 1 0 TMEM154 protein family Glyco_hydro_61 PF03443.14 KXS19366.1 - 2.4e-31 109.3 0.0 3.7e-31 108.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF3040 PF11239.8 KXS19366.1 - 0.065 13.5 0.3 0.14 12.4 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) AMP-binding PF00501.28 KXS19367.1 - 4.5e-71 239.7 0.0 6.5e-71 239.1 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 KXS19367.1 - 2e-66 223.8 0.0 3.2e-66 223.1 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.25 KXS19367.1 - 5e-12 46.0 0.0 1.6e-11 44.3 0.0 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.21 KXS19367.1 - 4.9e-10 39.3 0.0 9.7e-10 38.3 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXS19367.1 - 9.5e-09 34.7 0.0 2.2e-08 33.5 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Condensation PF00668.20 KXS19367.1 - 2.7e-08 32.9 0.0 0.0073 15.0 0.0 3.0 3 0 0 3 3 3 2 Condensation domain AMP-binding_C PF13193.6 KXS19367.1 - 6.5e-07 30.2 0.0 3.2e-06 28.0 0.0 2.3 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Polysacc_synt_2 PF02719.15 KXS19367.1 - 0.0016 17.6 0.1 0.019 14.1 0.0 2.1 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KXS19367.1 - 0.0051 16.3 0.0 0.0079 15.6 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase SH3_9 PF14604.6 KXS19368.1 - 0.0016 18.2 0.0 0.0031 17.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KXS19369.1 - 0.00024 20.9 0.4 0.0074 16.1 0.0 2.8 3 0 0 3 3 3 1 Variant SH3 domain Rax2 PF12768.7 KXS19369.1 - 0.012 15.1 0.1 0.017 14.6 0.1 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity SKG6 PF08693.10 KXS19369.1 - 0.11 11.9 0.5 0.24 10.9 0.5 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain TrbL PF04610.14 KXS19369.1 - 0.17 11.6 1.4 0.25 11.1 1.4 1.1 1 0 0 1 1 1 0 TrbL/VirB6 plasmid conjugal transfer protein Phage_holin_2_3 PF16080.5 KXS19369.1 - 0.4 10.5 2.0 7.4 6.4 0.2 2.7 1 1 1 2 2 2 0 Bacteriophage holin family HP1 Stig1 PF04885.13 KXS19369.1 - 3.6 8.1 23.9 22 5.5 23.9 2.1 1 1 0 1 1 1 0 Stigma-specific protein, Stig1 SH3_9 PF14604.6 KXS19371.1 - 0.0019 18.0 0.1 0.0045 16.8 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXS19371.1 - 0.033 13.8 0.0 0.062 12.9 0.0 1.4 1 0 0 1 1 1 0 SH3 domain Apt1 PF10351.9 KXS19371.1 - 0.12 11.2 6.2 0.2 10.5 6.2 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain GTP_EFTU PF00009.27 KXS19372.1 - 1.6e-43 148.6 0.0 4.5e-43 147.1 0.0 1.7 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KXS19372.1 - 8.4e-32 109.8 1.4 3.9e-31 107.7 0.1 2.5 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KXS19372.1 - 3.2e-10 40.3 0.4 8.4e-10 38.9 0.4 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.6 KXS19372.1 - 0.001 18.9 0.2 0.0034 17.2 0.2 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.23 KXS19372.1 - 0.0038 17.3 0.0 0.033 14.3 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase PAM2 PF07145.15 KXS19372.1 - 0.078 12.7 0.5 0.24 11.2 0.5 1.8 1 0 0 1 1 1 0 Ataxin-2 C-terminal region SOG2 PF10428.9 KXS19372.1 - 0.23 10.6 8.3 0.34 10.1 8.3 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein NAM-associated PF14303.6 KXS19372.1 - 8 7.1 8.6 3.2 8.4 3.5 2.3 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain PPR_2 PF13041.6 KXS19373.1 - 0.011 16.0 0.1 4.9 7.4 0.1 3.3 3 0 0 3 3 3 0 PPR repeat family PPR_3 PF13812.6 KXS19373.1 - 0.73 10.0 2.0 27 5.0 0.1 3.4 4 0 0 4 4 4 0 Pentatricopeptide repeat domain MFS_1 PF07690.16 KXS19375.1 - 8.6e-42 143.3 38.2 8.6e-42 143.3 38.2 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Bac_globin PF01152.21 KXS19376.1 - 2.7e-32 111.5 0.0 4e-32 110.9 0.0 1.2 1 0 0 1 1 1 1 Bacterial-like globin IBR PF01485.21 KXS19377.1 - 1.2e-19 70.3 47.1 1.5e-11 44.3 6.4 4.5 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 KXS19377.1 - 0.0054 16.6 4.3 0.0054 16.6 4.3 4.3 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) YhfH PF14149.6 KXS19377.1 - 0.02 14.9 7.5 0.11 12.5 7.5 2.3 1 0 0 1 1 1 0 YhfH-like protein UBA_4 PF14555.6 KXS19377.1 - 0.045 13.6 0.1 0.2 11.5 0.0 2.1 2 0 0 2 2 2 0 UBA-like domain zf-C3HC4_4 PF15227.6 KXS19377.1 - 5.4 7.3 27.0 0.15 12.3 0.4 4.2 3 1 0 3 3 3 0 zinc finger of C3HC4-type, RING Fungal_trans PF04082.18 KXS19378.1 - 1.9e-14 53.3 0.2 4.3e-14 52.2 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXS19378.1 - 1.3e-06 28.4 10.8 2.2e-06 27.7 10.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4524 PF15025.6 KXS19379.1 - 1.7e-13 50.6 0.1 3.3e-13 49.6 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4524) C2 PF00168.30 KXS19380.1 - 6.9e-09 35.9 0.0 9.2e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 C2 domain UQ_con PF00179.26 KXS19382.1 - 1.3e-44 151.2 0.0 1.4e-44 151.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KXS19382.1 - 0.002 17.8 0.0 0.0025 17.5 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KXS19382.1 - 0.0047 17.2 0.0 0.0066 16.7 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.13 KXS19382.1 - 0.016 15.1 0.2 0.026 14.4 0.2 1.3 1 1 0 1 1 1 0 UEV domain Zn-ribbon_8 PF09723.10 KXS19383.1 - 0.00038 20.5 2.5 0.00057 19.9 2.5 1.2 1 0 0 1 1 1 1 Zinc ribbon domain zf-RRPl_C4 PF17026.5 KXS19383.1 - 0.006 16.7 0.4 0.0072 16.4 0.4 1.2 1 0 0 1 1 1 1 Putative ribonucleoprotein zinc-finger pf C4 type zinc_ribbon_4 PF13717.6 KXS19383.1 - 0.015 15.2 6.5 0.82 9.7 0.7 2.7 3 0 0 3 3 3 0 zinc-ribbon domain zf-FPG_IleRS PF06827.14 KXS19383.1 - 0.015 15.1 0.8 0.036 13.9 0.5 1.8 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS HypA PF01155.19 KXS19383.1 - 0.016 15.2 0.3 0.021 14.8 0.3 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA NOB1_Zn_bind PF08772.11 KXS19383.1 - 0.022 14.9 0.1 0.023 14.8 0.1 1.3 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like zf-UDP PF14569.6 KXS19383.1 - 0.03 14.4 1.2 0.042 14.0 1.2 1.3 1 0 0 1 1 1 0 Zinc-binding RING-finger zinc_ribbon_9 PF14369.6 KXS19383.1 - 0.046 14.0 2.6 0.093 13.0 2.6 1.6 1 1 0 1 1 1 0 zinc-ribbon Zn_Tnp_IS1595 PF12760.7 KXS19383.1 - 0.048 13.6 1.7 3.1 7.8 0.1 2.5 2 0 0 2 2 2 0 Transposase zinc-ribbon domain DpnI PF06044.12 KXS19383.1 - 0.07 12.8 0.6 0.079 12.6 0.6 1.2 1 0 0 1 1 1 0 Dam-replacing family zf-C2H2_4 PF13894.6 KXS19383.1 - 0.31 12.0 3.5 5.8 8.0 0.5 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger Cys_rich_KTR PF14205.6 KXS19383.1 - 0.33 10.8 0.1 0.33 10.8 0.1 2.4 2 1 1 3 3 3 0 Cysteine-rich KTR zf-DNL PF05180.12 KXS19383.1 - 2.5 8.1 6.5 19 5.3 6.4 2.1 1 1 0 1 1 1 0 DNL zinc finger zf-ribbon_3 PF13248.6 KXS19383.1 - 2.9 7.4 6.5 4.5 6.8 1.4 2.3 1 1 0 2 2 2 0 zinc-ribbon domain zf-C2H2 PF00096.26 KXS19383.1 - 4.9 7.8 7.4 1.9 9.1 1.0 2.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type Baculo_PEP_C PF04513.12 KXS19384.1 - 0.026 14.5 0.6 0.054 13.5 0.6 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2827 PF10933.8 KXS19384.1 - 0.17 10.6 0.1 4.7 5.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2827) PCI PF01399.27 KXS19385.1 - 0.02 15.4 0.0 0.053 14.0 0.0 1.7 1 0 0 1 1 1 0 PCI domain Rpn3_C PF08375.11 KXS19386.1 - 3.3e-24 85.1 0.3 3.3e-24 85.1 0.3 1.9 2 0 0 2 2 2 1 Proteasome regulatory subunit C-terminal PCI PF01399.27 KXS19386.1 - 4.3e-21 75.4 2.7 6.3e-21 74.9 0.1 2.6 4 0 0 4 4 4 1 PCI domain TPR_2 PF07719.17 KXS19386.1 - 0.068 13.3 0.7 0.31 11.3 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 KXS19386.1 - 0.074 13.7 0.3 11 6.7 0.0 3.3 2 1 0 2 2 2 0 Tetratricopeptide repeat Pkinase PF00069.25 KXS19388.1 - 9.7e-46 156.3 0.0 1.1e-44 152.8 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS19388.1 - 3.9e-21 75.5 0.0 5.6e-21 75.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXS19388.1 - 0.26 10.6 0.0 15 4.8 0.0 2.2 2 0 0 2 2 2 0 Kinase-like DEAD PF00270.29 KXS19389.1 - 3.6e-44 150.6 0.5 5.2e-44 150.1 0.5 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXS19389.1 - 2.5e-28 98.6 2.6 5.9e-28 97.4 0.5 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 KXS19389.1 - 0.016 14.5 0.1 0.024 13.9 0.1 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase AAA PF00004.29 KXS19389.1 - 0.024 15.0 0.4 0.64 10.5 0.4 2.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) UvrD-helicase PF00580.21 KXS19389.1 - 0.078 12.5 0.1 0.17 11.3 0.1 1.5 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain CMS1 PF14617.6 KXS19389.1 - 0.094 12.0 0.1 0.2 11.0 0.1 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit SNF2_N PF00176.23 KXS19390.1 - 7.2e-71 238.7 0.2 1.3e-70 237.9 0.2 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 KXS19390.1 - 4.2e-36 123.4 3.5 4.2e-36 123.4 3.5 3.4 3 0 0 3 3 3 1 SLIDE HAND PF09110.11 KXS19390.1 - 4.4e-21 75.7 4.0 4.4e-21 75.7 4.0 2.6 2 0 0 2 2 2 1 HAND Helicase_C PF00271.31 KXS19390.1 - 1.7e-16 60.5 0.0 6.1e-16 58.8 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXS19390.1 - 2.3e-09 37.5 0.0 8.7e-09 35.6 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 KXS19390.1 - 5e-05 22.6 0.0 0.00012 21.4 0.0 1.6 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 KXS19390.1 - 0.00025 20.9 0.0 0.002 17.9 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase DBINO PF13892.6 KXS19390.1 - 0.047 14.0 0.6 0.047 14.0 0.6 3.8 4 0 0 4 4 4 0 DNA-binding domain Myb_DNA-binding PF00249.31 KXS19390.1 - 0.052 13.8 5.1 4.8 7.4 0.0 3.5 3 0 0 3 3 3 0 Myb-like DNA-binding domain PBP1_TM PF14812.6 KXS19390.1 - 0.26 11.7 0.0 0.26 11.7 0.0 4.2 4 0 0 4 4 4 0 Transmembrane domain of transglycosylase PBP1 at N-terminal AAA_6 PF12774.7 KXS19391.1 - 2.4e-104 348.8 0.2 3.4e-102 341.8 0.0 3.5 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 KXS19391.1 - 1e-52 179.6 10.8 2.5e-49 168.5 0.4 6.2 4 2 2 6 6 4 2 Dynein heavy chain, N-terminal region 2 AAA_5 PF07728.14 KXS19391.1 - 9.4e-28 96.9 0.0 2.3e-13 50.3 0.0 6.3 5 1 0 5 5 5 3 AAA domain (dynein-related subfamily) Dynein_heavy PF03028.15 KXS19391.1 - 9.9e-25 86.9 2.1 3.1e-24 85.3 0.7 2.7 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain AAA_8 PF12780.7 KXS19391.1 - 2.6e-20 72.9 2.5 1.8e-18 66.8 0.0 3.0 3 0 0 3 3 3 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 KXS19391.1 - 1.3e-19 70.2 30.5 4.8e-13 48.8 6.8 5.8 4 1 1 5 5 5 2 ATP-binding dynein motor region MT PF12777.7 KXS19391.1 - 4.7e-15 55.5 14.9 2.9e-14 52.9 14.9 2.3 1 1 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_7 PF12775.7 KXS19391.1 - 8.3e-12 45.0 2.2 0.011 15.3 0.0 4.8 4 0 0 4 4 4 3 P-loop containing dynein motor region AAA_22 PF13401.6 KXS19391.1 - 7e-09 36.1 4.7 0.27 11.5 0.0 6.2 5 0 0 5 5 4 2 AAA domain AAA PF00004.29 KXS19391.1 - 1.8e-08 34.9 0.2 0.77 10.2 0.0 5.3 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_lid_11 PF18198.1 KXS19391.1 - 2.4e-07 30.7 0.0 1e-06 28.7 0.0 2.1 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_16 PF13191.6 KXS19391.1 - 2.6e-07 31.2 7.6 0.0062 16.9 0.0 6.1 6 0 0 6 6 4 1 AAA ATPase domain AAA_18 PF13238.6 KXS19391.1 - 1.8e-05 25.3 0.5 0.6 10.7 0.0 5.7 6 0 0 6 6 5 1 AAA domain ABC_tran PF00005.27 KXS19391.1 - 0.00024 21.6 10.6 0.075 13.6 0.0 4.5 5 0 0 5 5 3 2 ABC transporter DUF815 PF05673.13 KXS19391.1 - 0.00027 20.2 2.1 0.67 9.1 0.1 3.9 4 0 0 4 4 4 2 Protein of unknown function (DUF815) AAA_30 PF13604.6 KXS19391.1 - 0.00029 20.6 0.1 2.4 7.8 0.0 3.7 3 0 0 3 3 3 1 AAA domain AAA_24 PF13479.6 KXS19391.1 - 0.0041 16.9 5.4 0.22 11.2 0.0 4.3 4 0 0 4 4 4 1 AAA domain AAA_29 PF13555.6 KXS19391.1 - 0.0074 16.0 6.0 0.41 10.4 0.0 3.6 4 0 0 4 4 3 1 P-loop containing region of AAA domain AAA_14 PF13173.6 KXS19391.1 - 0.0084 16.1 0.1 1.9 8.5 0.0 4.5 4 0 0 4 4 4 1 AAA domain Mg_chelatase PF01078.21 KXS19391.1 - 0.063 12.6 0.1 0.82 9.0 0.0 2.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ATP_bind_1 PF03029.17 KXS19391.1 - 0.086 12.6 1.1 65 3.2 0.0 4.6 4 0 0 4 4 4 0 Conserved hypothetical ATP binding protein TsaE PF02367.17 KXS19391.1 - 0.1 12.6 0.9 25 4.9 0.0 3.4 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase_2 PF01637.18 KXS19391.1 - 0.16 11.8 12.0 0.82 9.5 0.0 5.1 4 0 0 4 4 4 0 ATPase domain predominantly from Archaea AAA_19 PF13245.6 KXS19391.1 - 0.2 12.0 3.1 53 4.1 0.0 4.4 4 0 0 4 4 4 0 AAA domain DUF1415 PF07209.12 KXS19391.1 - 0.64 9.7 5.8 0.35 10.6 1.7 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1415) NPV_P10 PF05531.12 KXS19391.1 - 5.4 7.6 16.2 5.3 7.6 0.8 6.4 5 1 0 5 5 5 0 Nucleopolyhedrovirus P10 protein Homeodomain PF00046.29 KXS19392.1 - 0.028 14.2 0.0 0.04 13.8 0.0 1.1 1 0 0 1 1 1 0 Homeodomain AAA_5 PF07728.14 KXS19393.1 - 5.4e-91 301.8 0.1 9.1e-34 116.4 0.0 4.4 4 0 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KXS19393.1 - 6.4e-11 42.9 4.8 0.019 15.4 0.0 5.5 5 1 1 6 6 5 2 AAA ATPase domain CbbQ_C PF08406.10 KXS19393.1 - 7.2e-08 32.6 0.2 0.0041 17.3 0.1 3.7 3 0 0 3 3 3 2 CbbQ/NirQ/NorQ C-terminal AAA_22 PF13401.6 KXS19393.1 - 6.7e-05 23.2 0.0 0.29 11.4 0.0 3.8 2 1 0 2 2 2 1 AAA domain TsaE PF02367.17 KXS19393.1 - 0.00069 19.6 0.0 0.55 10.2 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA PF00004.29 KXS19393.1 - 0.002 18.5 0.0 2.4 8.6 0.0 3.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_3 PF07726.11 KXS19393.1 - 0.0042 16.9 0.0 8.4 6.3 0.0 3.5 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Med29 PF11568.8 KXS19393.1 - 0.0053 17.0 1.0 0.012 15.8 1.0 1.5 1 0 0 1 1 1 1 Mediator complex subunit 29 AAA_7 PF12775.7 KXS19393.1 - 0.0077 15.8 0.0 5.5 6.5 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region Roc PF08477.13 KXS19393.1 - 0.0079 16.4 0.0 6.8 6.9 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 KXS19393.1 - 0.0087 16.6 0.3 10 6.6 0.0 3.8 4 0 0 4 4 4 0 ABC transporter AAA_29 PF13555.6 KXS19393.1 - 0.013 15.2 0.0 5.5 6.8 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF4838 PF16126.5 KXS19393.1 - 0.062 12.7 0.2 0.23 10.8 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4838) Mg_chelatase PF01078.21 KXS19393.1 - 0.069 12.5 1.4 9.2 5.6 0.0 4.0 3 1 1 4 4 4 0 Magnesium chelatase, subunit ChlI RsgA_GTPase PF03193.16 KXS19393.1 - 0.076 12.9 0.0 14 5.6 0.0 2.6 2 0 0 2 2 2 0 RsgA GTPase DUF815 PF05673.13 KXS19393.1 - 0.084 12.0 0.0 2.6 7.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) TniB PF05621.11 KXS19393.1 - 0.088 12.2 0.1 18 4.7 0.0 3.0 3 0 0 3 3 3 0 Bacterial TniB protein NACHT PF05729.12 KXS19393.1 - 0.1 12.5 0.1 4.3 7.2 0.0 3.2 3 1 0 3 3 3 0 NACHT domain TIP49 PF06068.13 KXS19393.1 - 0.1 11.8 0.0 4.4 6.4 0.0 2.9 3 0 0 3 3 3 0 TIP49 P-loop domain RNA_helicase PF00910.22 KXS19393.1 - 0.11 12.8 0.0 5.7 7.4 0.0 2.6 2 0 0 2 2 2 0 RNA helicase Keratin_2_head PF16208.5 KXS19393.1 - 1.1 9.4 14.9 2 8.5 14.9 1.3 1 0 0 1 1 1 0 Keratin type II head CATSPERB PF15149.6 KXS19395.1 - 2.9e-56 191.1 0.3 7.4e-52 176.6 0.1 2.1 2 0 0 2 2 2 2 Cation channel sperm-associated protein subunit beta protein family MOSC PF03473.17 KXS19396.1 - 6.9e-25 87.6 0.1 1.3e-24 86.7 0.1 1.5 1 0 0 1 1 1 1 MOSC domain Aminotran_5 PF00266.19 KXS19396.1 - 5.9e-18 65.0 0.0 6e-09 35.3 0.0 4.1 4 0 0 4 4 4 4 Aminotransferase class-V MOSC_N PF03476.16 KXS19396.1 - 2.9e-12 46.5 0.0 8.2e-12 45.1 0.0 1.8 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain CCDC158 PF15921.5 KXS19396.1 - 0.029 12.2 0.0 0.029 12.2 0.0 1.4 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 158 Caudo_bapla16 PF16792.5 KXS19396.1 - 0.24 10.4 0.1 0.35 9.8 0.1 1.1 1 0 0 1 1 1 0 Phage tail base-plate attachment protein of Caudovirales ORF16 TetR_C_33 PF13305.6 KXS19397.1 - 0.019 15.7 0.0 0.03 15.1 0.0 1.3 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain MFMR_assoc PF16596.5 KXS19397.1 - 0.44 11.0 8.6 0.64 10.5 8.6 1.2 1 0 0 1 1 1 0 Disordered region downstream of MFMR DNA_pol_phi PF04931.13 KXS19398.1 - 4 5.4 7.8 6.9 4.6 7.8 1.3 1 0 0 1 1 1 0 DNA polymerase phi DUF4551 PF15087.6 KXS19399.1 - 0.46 9.2 1.7 0.69 8.7 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Raftlin PF15250.6 KXS19399.1 - 0.63 8.7 8.9 0.83 8.3 8.9 1.1 1 0 0 1 1 1 0 Raftlin Nop14 PF04147.12 KXS19399.1 - 1.6 6.9 25.1 2 6.6 25.1 1.1 1 0 0 1 1 1 0 Nop14-like family Neur_chan_memb PF02932.16 KXS19399.1 - 2.2 8.3 4.1 3.3 7.7 4.1 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CobT PF06213.12 KXS19399.1 - 4.5 6.6 22.6 15 4.9 22.7 2.0 1 1 0 1 1 1 0 Cobalamin biosynthesis protein CobT Cyclin PF08613.11 KXS19400.1 - 6.9e-09 36.3 0.0 1e-08 35.7 0.0 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 KXS19400.1 - 2.3e-05 24.1 0.0 0.0019 17.9 0.0 2.1 2 0 0 2 2 2 2 Cyclin, N-terminal domain DUF1298 PF06974.13 KXS19401.1 - 4.6e-16 59.1 0.0 7.9e-16 58.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1298) WES_acyltransf PF03007.16 KXS19401.1 - 8.3e-10 38.9 0.1 1.3e-09 38.2 0.1 1.3 1 0 0 1 1 1 1 Wax ester synthase-like Acyl-CoA acyltransferase domain Condensation PF00668.20 KXS19401.1 - 0.00018 20.4 0.0 0.00069 18.4 0.0 1.7 2 0 0 2 2 2 1 Condensation domain zf-C2H2 PF00096.26 KXS19402.1 - 2.6e-08 33.9 13.1 0.00074 19.8 2.6 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KXS19402.1 - 3.8e-07 30.2 12.9 5.8e-05 23.3 2.5 3.7 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KXS19402.1 - 4e-07 30.3 10.7 0.0047 17.6 1.7 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 KXS19402.1 - 0.016 14.9 0.6 0.04 13.6 0.6 1.6 1 0 0 1 1 1 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2HC_2 PF13913.6 KXS19402.1 - 0.093 12.7 0.5 0.093 12.7 0.5 2.8 3 0 0 3 3 3 0 zinc-finger of a C2HC-type SAD_SRA PF02182.17 KXS19403.1 - 2.2e-49 167.2 0.1 4e-49 166.3 0.1 1.4 1 0 0 1 1 1 1 SAD/SRA domain zf-C3HC4_3 PF13920.6 KXS19403.1 - 8.6e-09 35.1 7.5 8.6e-09 35.1 7.5 3.6 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXS19403.1 - 7.6e-08 32.1 11.4 7.6e-08 32.1 11.4 3.1 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXS19403.1 - 8.7e-08 31.9 10.4 8.7e-08 31.9 10.4 3.1 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 KXS19403.1 - 7.5e-06 25.7 17.0 7.5e-06 25.7 17.0 3.7 2 2 1 3 3 3 1 PHD-finger zf-RING_UBOX PF13445.6 KXS19403.1 - 1.2e-05 25.2 8.8 1.2e-05 25.2 8.8 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KXS19403.1 - 1.9e-05 24.7 8.6 1.9e-05 24.7 8.6 2.9 3 1 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 KXS19403.1 - 5.6e-05 23.0 9.8 5.6e-05 23.0 9.8 3.3 2 1 1 3 3 3 1 zinc-RING finger domain zf-RING_2 PF13639.6 KXS19403.1 - 0.00091 19.5 9.3 0.00091 19.5 9.3 2.6 2 0 0 2 2 2 1 Ring finger domain ubiquitin PF00240.23 KXS19403.1 - 0.059 13.1 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin family TLP1_add_C PF18313.1 KXS19404.1 - 2.3e-24 85.1 0.0 4.1e-24 84.3 0.0 1.4 1 0 0 1 1 1 1 Thiolase-like protein type 1 additional C-terminal domain DAGAT PF03982.13 KXS19405.1 - 6.8e-96 320.7 0.0 8.6e-96 320.3 0.0 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Pyr_redox_2 PF07992.14 KXS19406.1 - 6.8e-55 186.4 0.7 1.5e-54 185.2 0.7 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KXS19406.1 - 1.5e-33 115.4 1.7 2.8e-33 114.5 0.6 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KXS19406.1 - 1.5e-14 54.3 1.4 3e-12 46.9 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXS19406.1 - 2.8e-11 43.2 1.3 2.6e-10 40.1 1.3 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KXS19406.1 - 2e-06 27.2 4.3 0.0024 17.0 4.2 2.9 2 1 0 2 2 2 2 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 KXS19406.1 - 8.5e-06 25.2 0.3 0.054 12.8 0.0 2.8 3 0 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 KXS19406.1 - 1.9e-05 24.2 0.1 2.8e-05 23.7 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 KXS19406.1 - 0.00011 22.6 0.1 0.2 12.1 0.0 2.6 2 0 0 2 2 2 2 Putative NAD(P)-binding FAD_binding_3 PF01494.19 KXS19406.1 - 0.00068 19.0 2.9 0.25 10.5 0.2 2.3 2 0 0 2 2 2 2 FAD binding domain HI0933_like PF03486.14 KXS19406.1 - 0.00075 18.3 3.1 0.014 14.1 0.3 2.7 3 0 0 3 3 3 1 HI0933-like protein FAD_binding_2 PF00890.24 KXS19406.1 - 0.0036 16.4 3.7 0.0053 15.9 1.0 2.4 3 0 0 3 3 3 1 FAD binding domain K_oxygenase PF13434.6 KXS19406.1 - 0.0091 15.2 0.0 0.016 14.3 0.0 1.5 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KXS19406.1 - 0.079 13.2 8.0 0.21 11.8 2.8 2.8 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain 2-Hacid_dh_C PF02826.19 KXS19406.1 - 0.1 12.0 2.5 0.28 10.5 0.0 2.5 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 KXS19406.1 - 0.11 12.4 0.0 0.11 12.4 0.0 2.7 4 0 0 4 4 4 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DAO PF01266.24 KXS19406.1 - 0.18 11.4 10.0 0.19 11.3 0.9 2.9 3 0 0 3 3 3 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KXS19406.1 - 0.83 9.6 2.3 2.4 8.1 0.0 2.7 4 0 0 4 4 4 0 FAD-NAD(P)-binding NYD-SP28_assoc PF14775.6 KXS19407.1 - 0.37 10.9 4.2 11 6.2 0.1 2.5 2 0 0 2 2 2 0 Sperm tail C-terminal domain DUF4407 PF14362.6 KXS19407.1 - 0.54 9.6 5.8 1.1 8.6 5.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4140 PF13600.6 KXS19407.1 - 0.6 10.6 14.5 0.46 11.0 4.2 3.5 3 1 1 4 4 4 0 N-terminal domain of unknown function (DUF4140) ZapB PF06005.12 KXS19407.1 - 0.68 10.4 15.4 0.41 11.1 3.8 2.4 2 0 0 2 2 2 0 Cell division protein ZapB JIP_LZII PF16471.5 KXS19407.1 - 1.1 9.4 8.3 0.5 10.6 1.6 2.5 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II GAS PF13851.6 KXS19407.1 - 3.1 7.1 16.4 5.4 6.3 16.4 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Gtr1_RagA PF04670.12 KXS19408.1 - 1.5e-98 328.8 0.0 2e-98 328.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 KXS19408.1 - 9.7e-10 38.7 0.0 2.2e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KXS19408.1 - 2e-08 34.0 0.0 4e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Ras family Arf PF00025.21 KXS19408.1 - 1.7e-07 30.9 0.0 2.6e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KXS19408.1 - 7.1e-07 29.3 0.0 2.1e-06 27.8 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KXS19408.1 - 0.0036 17.2 0.3 2.9 7.8 0.0 2.6 2 1 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 KXS19408.1 - 0.0073 15.8 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit ABC_tran PF00005.27 KXS19408.1 - 0.032 14.7 0.1 0.098 13.2 0.1 1.7 1 1 0 1 1 1 0 ABC transporter PduV-EutP PF10662.9 KXS19408.1 - 0.033 13.9 0.1 0.11 12.2 0.1 1.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF815 PF05673.13 KXS19408.1 - 0.059 12.5 0.0 0.12 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_24 PF13479.6 KXS19408.1 - 0.12 12.1 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain Prefoldin_2 PF01920.20 KXS19408.1 - 0.19 11.7 0.8 0.8 9.7 0.0 2.0 2 0 0 2 2 2 0 Prefoldin subunit G-alpha PF00503.20 KXS19408.1 - 0.27 10.3 6.1 3.2 6.8 0.0 2.7 2 1 1 3 3 3 0 G-protein alpha subunit ATG16 PF08614.11 KXS19409.1 - 8.4e-31 107.8 23.5 8.4e-31 107.8 23.5 2.0 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) WD40 PF00400.32 KXS19409.1 - 4.3e-24 84.3 23.1 3e-05 24.7 0.3 7.4 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXS19409.1 - 5.4e-13 49.0 0.9 0.034 14.4 0.0 5.9 1 1 3 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KXS19409.1 - 6e-07 28.5 4.4 0.039 12.6 0.2 4.3 2 1 2 4 4 4 3 Nucleoporin Nup120/160 WD40_like PF17005.5 KXS19409.1 - 0.0023 17.3 0.0 0.64 9.3 0.0 2.3 2 0 0 2 2 2 2 WD40-like domain KIAA1430 PF13879.6 KXS19409.1 - 0.012 16.4 10.9 0.018 15.8 10.1 1.7 1 1 0 1 1 1 0 KIAA1430 homologue CCDC168_N PF15804.5 KXS19409.1 - 0.093 12.6 8.0 0.15 11.9 8.0 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 168 RNA_pol_Rpb1_2 PF00623.20 KXS19409.1 - 0.19 11.9 4.9 1.4 9.1 0.2 2.4 1 1 1 2 2 2 0 RNA polymerase Rpb1, domain 2 zf-C4H2 PF10146.9 KXS19409.1 - 0.21 11.8 8.2 0.38 11.0 8.2 1.4 1 0 0 1 1 1 0 Zinc finger-containing protein V_ATPase_I PF01496.19 KXS19409.1 - 0.32 8.9 6.7 0.42 8.5 6.7 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Orbi_VP5 PF00901.17 KXS19409.1 - 1.8 6.8 6.9 2.6 6.3 6.9 1.2 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 AFG1_ATPase PF03969.16 KXS19411.1 - 2.8e-105 352.2 0.0 1.2e-100 337.0 0.0 2.8 2 1 0 2 2 2 2 AFG1-like ATPase AAA PF00004.29 KXS19411.1 - 1.1e-05 25.8 0.0 0.011 16.2 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KXS19411.1 - 2.4e-05 24.8 0.8 0.047 14.1 0.0 3.3 2 1 2 4 4 4 2 AAA ATPase domain Bac_DnaA PF00308.18 KXS19411.1 - 7.2e-05 22.7 0.0 0.02 14.7 0.0 2.4 2 0 0 2 2 2 2 Bacterial dnaA protein AAA_14 PF13173.6 KXS19411.1 - 0.00017 21.6 0.0 0.00077 19.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KXS19411.1 - 0.0013 19.0 0.0 0.046 14.0 0.1 2.6 2 1 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 KXS19411.1 - 0.011 15.7 0.0 0.62 9.9 0.0 2.2 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea CTNNB1_binding PF08347.11 KXS19411.1 - 0.012 15.8 0.4 0.025 14.8 0.4 1.4 1 0 0 1 1 1 0 N-terminal CTNNB1 binding TniB PF05621.11 KXS19411.1 - 0.1 12.0 0.1 0.3 10.5 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein AAA_5 PF07728.14 KXS19411.1 - 0.13 12.3 0.0 0.55 10.2 0.0 2.1 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 KXS19411.1 - 0.13 12.6 0.0 3.6 8.0 0.0 2.5 2 0 0 2 2 2 0 RNA helicase Ureidogly_lyase PF04115.12 KXS19412.1 - 1.7e-37 129.0 0.0 2.4e-37 128.5 0.0 1.2 1 0 0 1 1 1 1 Ureidoglycolate lyase FAD_binding_3 PF01494.19 KXS19413.1 - 2.3e-21 76.4 0.0 3.5e-21 75.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KXS19413.1 - 1.8e-06 27.4 0.2 0.014 14.6 0.3 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXS19413.1 - 1.7e-05 24.6 0.6 0.0032 17.1 1.5 2.2 1 1 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KXS19413.1 - 0.00012 21.3 0.2 0.43 9.6 0.3 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein NAD_binding_8 PF13450.6 KXS19413.1 - 0.00026 21.1 0.6 0.00069 19.8 0.6 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KXS19413.1 - 0.0022 18.5 0.2 0.54 10.8 0.2 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXS19413.1 - 0.01 15.1 0.1 0.29 10.3 0.5 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXS19413.1 - 0.012 14.8 0.9 0.018 14.1 0.9 1.3 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.6 KXS19413.1 - 0.035 14.1 0.1 3.7 7.5 0.2 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding Thi4 PF01946.17 KXS19413.1 - 0.11 11.7 0.1 0.16 11.2 0.1 1.2 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.14 KXS19413.1 - 0.2 10.5 0.5 9.3 5.0 0.2 2.6 3 0 0 3 3 3 0 Tryptophan halogenase zf-H2C2_2 PF13465.6 KXS19414.1 - 1.2e-23 82.4 40.3 9.9e-08 32.1 0.1 8.6 9 0 0 9 9 8 5 Zinc-finger double domain zf-C2H2 PF00096.26 KXS19414.1 - 4.5e-16 58.3 80.2 5.7e-06 26.5 1.4 9.9 11 0 0 11 11 10 6 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KXS19414.1 - 7.7e-13 48.4 8.8 0.025 14.9 0.3 6.3 6 0 0 6 6 6 3 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 KXS19414.1 - 1.9e-10 40.7 26.9 0.00033 21.2 1.1 11.2 11 1 1 12 12 9 5 C2H2-type zinc finger zf-met PF12874.7 KXS19414.1 - 3.5e-07 30.4 10.7 0.39 11.2 0.4 5.8 5 0 0 5 5 5 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KXS19414.1 - 1.6e-05 24.8 24.2 0.13 12.3 1.1 6.8 6 0 0 6 6 6 3 C2H2-type zinc finger zf-LYAR PF08790.11 KXS19414.1 - 0.0094 15.8 4.6 3.2 7.7 0.1 5.2 5 0 0 5 5 5 1 LYAR-type C2HC zinc finger zf-DNA_Pol PF08996.10 KXS19414.1 - 0.13 12.0 6.2 0.27 11.0 0.4 3.5 2 1 2 4 4 4 0 DNA Polymerase alpha zinc finger zf-C2H2_aberr PF17017.5 KXS19414.1 - 0.46 10.6 10.5 12 6.0 0.1 4.8 5 1 0 5 5 5 0 Aberrant zinc-finger Ogr_Delta PF04606.12 KXS19414.1 - 0.77 9.8 7.3 0.95 9.5 1.1 3.6 3 0 0 3 3 3 0 Ogr/Delta-like zinc finger zf-C2H2_11 PF16622.5 KXS19414.1 - 3.2 7.6 16.6 1.9 8.3 0.1 5.3 5 0 0 5 5 5 0 zinc-finger C2H2-type Transthyretin PF00576.21 KXS19415.1 - 7.9e-40 136.0 0.0 8.9e-40 135.8 0.0 1.0 1 0 0 1 1 1 1 HIUase/Transthyretin family FAD_binding_3 PF01494.19 KXS19416.1 - 2.3e-21 76.4 0.0 3.5e-21 75.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KXS19416.1 - 1.8e-06 27.4 0.2 0.014 14.6 0.3 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXS19416.1 - 1.7e-05 24.6 0.6 0.0032 17.1 1.5 2.2 1 1 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KXS19416.1 - 0.00012 21.3 0.2 0.43 9.6 0.3 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein NAD_binding_8 PF13450.6 KXS19416.1 - 0.00026 21.1 0.6 0.00069 19.8 0.6 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KXS19416.1 - 0.0022 18.5 0.2 0.54 10.8 0.2 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXS19416.1 - 0.01 15.1 0.1 0.29 10.3 0.5 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXS19416.1 - 0.012 14.8 0.9 0.018 14.1 0.9 1.3 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.6 KXS19416.1 - 0.035 14.1 0.1 3.7 7.5 0.2 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding Thi4 PF01946.17 KXS19416.1 - 0.11 11.7 0.1 0.16 11.2 0.1 1.2 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.14 KXS19416.1 - 0.2 10.5 0.5 9.3 5.0 0.2 2.6 3 0 0 3 3 3 0 Tryptophan halogenase Mannosyl_trans3 PF11051.8 KXS19417.1 - 1.8e-41 142.3 0.0 2.6e-41 141.8 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative LRR_6 PF13516.6 KXS19418.1 - 2e-14 52.3 19.2 0.00032 20.5 0.1 6.3 7 0 0 7 7 7 5 Leucine Rich repeat LRR_4 PF12799.7 KXS19418.1 - 0.00042 20.6 6.7 1.2 9.7 0.1 4.4 3 2 2 5 5 5 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KXS19418.1 - 0.0061 16.9 2.2 38 5.4 0.0 4.7 6 0 0 6 6 6 2 Leucine Rich Repeat tRNA-synt_2 PF00152.20 KXS19419.1 - 5.4e-83 278.7 0.0 7e-83 278.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KXS19419.1 - 8e-07 29.0 0.0 2.3e-06 27.5 0.0 1.8 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain SAP30_Sin3_bdg PF13867.6 KXS19420.1 - 6.2e-16 58.5 0.0 8.1e-16 58.1 0.0 1.2 1 0 0 1 1 1 1 Sin3 binding region of histone deacetylase complex subunit SAP30 Rad17 PF03215.15 KXS19422.1 - 2.6e-23 82.9 0.0 8.1e-23 81.3 0.0 1.7 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 KXS19422.1 - 0.00017 22.0 0.0 0.00052 20.4 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KXS19422.1 - 0.0011 19.4 0.0 0.0028 18.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 KXS19422.1 - 0.0074 15.6 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_19 PF13245.6 KXS19422.1 - 0.0083 16.5 0.0 0.016 15.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KXS19422.1 - 0.0088 15.8 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 KXS19422.1 - 0.014 15.1 0.0 0.027 14.2 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain T2SSE PF00437.20 KXS19422.1 - 0.018 14.1 0.0 0.031 13.3 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein TsaE PF02367.17 KXS19422.1 - 0.027 14.5 0.0 0.051 13.6 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 KXS19422.1 - 0.039 14.2 0.0 0.082 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KXS19422.1 - 0.078 12.1 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.22 KXS19422.1 - 0.081 13.3 0.0 0.62 10.5 0.0 2.2 2 0 0 2 2 2 0 RNA helicase SRP54 PF00448.22 KXS19422.1 - 0.14 11.8 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ATPase_2 PF01637.18 KXS19422.1 - 0.14 12.0 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_18 PF13238.6 KXS19422.1 - 0.16 12.5 0.0 0.48 11.0 0.0 1.8 2 0 0 2 2 1 0 AAA domain Torsin PF06309.11 KXS19422.1 - 0.17 12.0 0.0 2.8 8.1 0.0 2.2 2 0 0 2 2 2 0 Torsin PIF1 PF05970.14 KXS19422.1 - 0.21 10.7 0.0 0.34 10.0 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase GDP_Man_Dehyd PF16363.5 KXS19423.1 - 9.1e-61 206.1 0.0 2.2e-60 204.8 0.0 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KXS19423.1 - 4.8e-48 163.7 0.0 6.7e-48 163.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXS19423.1 - 8e-08 31.6 0.0 1.1e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KXS19423.1 - 1.2e-07 31.2 0.0 1.6e-07 30.7 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 KXS19423.1 - 6.2e-07 28.8 0.1 0.0002 20.7 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.15 KXS19423.1 - 1.9e-06 27.3 0.3 0.0081 15.3 0.1 2.8 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein DIOX_N PF14226.6 KXS19425.1 - 0.029 15.1 0.0 0.049 14.4 0.0 1.3 1 0 0 1 1 1 0 non-haem dioxygenase in morphine synthesis N-terminal p450 PF00067.22 KXS19426.1 - 1.3e-64 218.6 0.0 1.9e-64 218.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Lipase_3 PF01764.25 KXS19429.1 - 1.9e-10 40.8 0.0 4e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KXS19429.1 - 0.00026 21.7 0.0 0.00026 21.7 0.0 2.5 3 1 0 3 3 3 1 Alpha/beta hydrolase family UPF0227 PF05728.12 KXS19429.1 - 0.002 18.1 0.0 0.0041 17.1 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) Abhydrolase_5 PF12695.7 KXS19429.1 - 0.012 15.3 0.0 0.023 14.5 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXS19429.1 - 0.017 14.4 0.0 0.033 13.5 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KXS19429.1 - 0.028 14.0 0.0 0.055 13.1 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF2974 PF11187.8 KXS19429.1 - 0.14 11.6 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Ald_Xan_dh_C2 PF02738.18 KXS19430.1 - 9.1e-189 628.4 0.2 1.4e-188 627.8 0.2 1.2 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.21 KXS19430.1 - 1.3e-46 158.5 0.0 2.4e-46 157.6 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.22 KXS19430.1 - 7.9e-31 106.7 0.2 2.3e-30 105.2 0.2 1.9 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.20 KXS19430.1 - 9.6e-28 96.0 0.1 2.4e-27 94.8 0.1 1.8 1 0 0 1 1 1 1 [2Fe-2S] binding domain CO_deh_flav_C PF03450.17 KXS19430.1 - 9.5e-27 93.2 0.0 3.4e-26 91.4 0.0 2.0 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain Fer2 PF00111.27 KXS19430.1 - 1.3e-06 28.2 2.2 3.5e-06 26.9 0.1 2.6 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain DUF5126 PF17166.4 KXS19430.1 - 0.12 12.3 0.0 0.48 10.3 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5126) Cys_Met_Meta_PP PF01053.20 KXS19431.1 - 1.1e-33 116.3 0.0 1.7e-33 115.7 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KXS19431.1 - 0.0021 17.3 0.0 0.0041 16.3 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II DUF3564 PF12087.8 KXS19431.1 - 0.12 12.3 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3564) WW PF00397.26 KXS19432.1 - 8.4e-15 54.6 8.6 3.8e-07 30.1 1.2 3.0 3 0 0 3 3 3 2 WW domain Fungal_TACC PF12709.7 KXS19432.1 - 2.3 8.7 13.8 2.1 8.8 7.5 2.9 2 0 0 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins T3SS_TC PF06511.11 KXS19432.1 - 2.8 7.2 10.6 0.047 13.1 1.3 2.3 2 0 0 2 2 2 0 Type III secretion systems tip complex components YabA PF06156.13 KXS19432.1 - 3.3 8.4 15.9 8.9 7.0 0.2 3.4 2 1 1 3 3 3 0 Initiation control protein YabA Pro_isomerase PF00160.21 KXS19433.1 - 1.2e-49 168.6 0.0 1.5e-49 168.3 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD CHCH PF06747.13 KXS19434.1 - 3.7e-06 26.9 4.8 5.2e-06 26.5 4.8 1.2 1 0 0 1 1 1 1 CHCH domain NDUF_B7 PF05676.13 KXS19434.1 - 0.00028 20.5 0.5 0.00036 20.2 0.5 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Pet191_N PF10203.9 KXS19434.1 - 0.008 16.5 3.9 0.028 14.7 3.9 1.7 1 1 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 COX17 PF05051.13 KXS19434.1 - 0.026 14.9 5.7 0.081 13.3 0.6 2.3 2 1 1 3 3 3 0 Cytochrome C oxidase copper chaperone (COX17) UPF0203 PF05254.12 KXS19434.1 - 0.029 14.6 3.0 0.31 11.3 0.4 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) Cmc1 PF08583.10 KXS19434.1 - 0.037 14.1 3.3 0.094 12.7 3.3 1.6 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like ABC_membrane PF00664.23 KXS19435.1 - 5.7e-35 121.3 16.0 5.7e-35 121.3 16.0 1.8 3 0 0 3 3 3 1 ABC transporter transmembrane region ABC_tran PF00005.27 KXS19435.1 - 1.3e-11 45.2 0.0 2.6e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 ABC transporter MTABC_N PF16185.5 KXS19435.1 - 5.6e-08 32.6 1.9 0.0027 17.2 0.1 2.9 2 1 0 2 2 2 2 Mitochondrial ABC-transporter N-terminal five TM region SMC_N PF02463.19 KXS19435.1 - 0.0011 18.5 0.0 0.0011 18.5 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 KXS19435.1 - 0.092 13.0 0.5 2.2 8.6 0.5 2.7 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Amastin PF07344.11 KXS19435.1 - 0.23 11.3 0.0 0.23 11.3 0.0 3.0 3 0 0 3 3 3 0 Amastin surface glycoprotein MMS1_N PF10433.9 KXS19436.1 - 6.7e-154 513.1 0.0 1e-153 512.5 0.0 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 KXS19436.1 - 1.4e-93 313.8 0.0 3e-91 306.1 0.0 2.4 2 0 0 2 2 2 2 CPSF A subunit region EZH2_N PF18601.1 KXS19438.1 - 0.12 12.7 0.1 0.25 11.7 0.0 1.5 1 1 0 1 1 1 0 EZH2 N-terminal domain Glycos_transf_1 PF00534.20 KXS19440.1 - 2e-20 73.0 0.0 3.4e-20 72.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KXS19440.1 - 1.1e-17 64.7 0.1 2.1e-17 63.8 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_hydro_61 PF03443.14 KXS19442.1 - 1.2e-45 156.0 0.1 2.4e-45 155.0 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DJ-1_PfpI PF01965.24 KXS19445.1 - 1.6e-22 80.1 0.1 2e-22 79.8 0.1 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family Ferric_reduct PF01794.19 KXS19446.1 - 3.7e-14 52.9 11.2 3.7e-14 52.9 11.2 2.5 3 0 0 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KXS19446.1 - 7.4e-05 22.9 0.0 0.0029 17.8 0.0 2.4 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KXS19446.1 - 0.0018 18.4 0.0 0.0034 17.4 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain DUF5600 PF18150.1 KXS19447.1 - 2.3e-22 79.6 0.0 3.8e-22 78.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5600) Dynamin_N PF00350.23 KXS19447.1 - 3.4e-11 43.5 0.0 1e-05 25.7 0.0 2.5 2 0 0 2 2 2 2 Dynamin family MMR_HSR1 PF01926.23 KXS19447.1 - 2.3e-06 27.7 0.0 8.9e-06 25.8 0.0 2.1 2 1 0 2 2 1 1 50S ribosome-binding GTPase Acetyltransf_1 PF00583.25 KXS19447.1 - 0.00033 20.9 0.0 0.00075 19.7 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXS19447.1 - 0.00087 19.2 0.1 0.0016 18.4 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GTP_EFTU PF00009.27 KXS19447.1 - 0.00097 18.7 0.0 0.0052 16.4 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Acetyltransf_9 PF13527.7 KXS19447.1 - 0.0017 18.5 0.0 0.0033 17.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain SDA1 PF05285.12 KXS19447.1 - 0.023 14.1 10.6 0.037 13.4 10.6 1.2 1 0 0 1 1 1 0 SDA1 cobW PF02492.19 KXS19447.1 - 0.025 14.2 0.0 1.8 8.1 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Acetyltransf_7 PF13508.7 KXS19447.1 - 0.031 14.7 0.0 0.063 13.7 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXS19447.1 - 0.035 14.1 0.0 0.081 12.9 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein TAF1D PF15333.6 KXS19447.1 - 0.081 12.7 0.7 0.35 10.6 0.8 2.0 2 0 0 2 2 2 0 TATA box-binding protein-associated factor 1D BUD22 PF09073.10 KXS19447.1 - 0.38 10.0 13.9 0.67 9.2 13.9 1.3 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 KXS19447.1 - 0.39 8.9 6.3 0.55 8.4 6.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 KXS19447.1 - 0.57 8.3 10.4 0.8 7.8 10.4 1.1 1 0 0 1 1 1 0 Nop14-like family Lin-8 PF03353.15 KXS19447.1 - 9.3 5.7 8.0 14 5.1 8.0 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist PHO4 PF01384.20 KXS19448.1 - 2.2e-118 395.2 14.9 2.6e-118 394.9 14.9 1.1 1 0 0 1 1 1 1 Phosphate transporter family DUF4149 PF13664.6 KXS19448.1 - 0.54 10.6 6.8 4 7.8 6.8 2.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4149) p450 PF00067.22 KXS19449.1 - 7.2e-31 107.4 0.0 1.5e-30 106.4 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 DUF1732 PF08340.11 KXS19449.1 - 0.13 12.2 0.1 0.25 11.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1732) DEC-1_N PF04625.13 KXS19450.1 - 0.00067 18.8 11.6 0.00067 18.8 11.6 2.3 2 0 0 2 2 2 2 DEC-1 protein, N-terminal region FAP PF07174.11 KXS19450.1 - 1.4 8.4 43.8 0.77 9.2 16.1 2.3 2 0 0 2 2 2 0 Fibronectin-attachment protein (FAP) Epimerase PF01370.21 KXS19451.1 - 1.7e-19 70.2 0.0 2.4e-19 69.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXS19451.1 - 3.9e-12 46.2 0.0 5.8e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KXS19451.1 - 1.5e-10 40.6 0.0 1.9e-10 40.2 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KXS19451.1 - 5.4e-08 32.3 0.0 7.2e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 KXS19451.1 - 6.8e-07 29.4 0.0 9.8e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KXS19451.1 - 1.1e-06 28.0 0.1 6.1e-05 22.3 0.1 3.2 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 KXS19451.1 - 1.1e-06 28.0 0.0 3.2e-06 26.5 0.0 1.7 2 1 0 2 2 2 1 Male sterility protein Tachykinin PF02202.16 KXS19451.1 - 0.082 12.8 1.2 0.22 11.5 1.2 1.8 1 0 0 1 1 1 0 Tachykinin family Cnd2 PF05786.14 KXS19452.1 - 0.23 10.1 16.9 0.24 10.0 16.9 1.1 1 0 0 1 1 1 0 Condensin complex subunit 2 Nop53 PF07767.11 KXS19452.1 - 1.8 7.9 18.1 1.8 7.8 18.1 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) RPN2_C PF18004.1 KXS19452.1 - 3.8 7.4 13.0 4.6 7.1 13.0 1.1 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain CCDC106 PF15794.5 KXS19452.1 - 4.2 7.0 8.1 4.4 6.9 8.1 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 DUF3381 PF11861.8 KXS19452.1 - 6.5 6.5 15.5 6.9 6.4 15.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) SURF2 PF05477.11 KXS19452.1 - 8.3 6.0 13.8 9.3 5.9 13.8 1.1 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) TFIIF_alpha PF05793.12 KXS19452.1 - 9.7 4.6 26.4 11 4.5 26.4 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CTD PF12815.7 KXS19453.1 - 1.2e-14 54.6 30.9 1.8e-10 41.2 13.3 3.5 1 1 1 3 3 3 2 Spt5 C-terminal nonapeptide repeat binding Spt4 Spt5-NGN PF03439.13 KXS19453.1 - 3.4e-13 49.3 0.0 8.2e-13 48.1 0.0 1.6 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.29 KXS19453.1 - 1.2e-06 28.2 42.2 0.039 13.9 0.1 7.7 7 1 0 7 7 7 4 KOW motif DUF3006 PF11213.8 KXS19453.1 - 0.00026 21.1 0.1 0.043 14.0 0.0 3.3 3 1 0 3 3 3 1 Protein of unknown function (DUF3006) SH3_15 PF18346.1 KXS19453.1 - 0.24 11.7 1.1 1.9 8.8 0.0 3.1 3 1 0 3 3 3 0 Mind bomb SH3 repeat domain MFS_1 PF07690.16 KXS19454.1 - 4.9e-27 94.8 33.4 6.4e-27 94.4 32.9 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXS19454.1 - 1.8e-06 27.1 24.2 0.0014 17.6 3.3 2.2 1 1 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.6 KXS19454.1 - 7.1e-06 24.8 5.0 7.1e-06 24.8 5.0 2.3 2 1 0 2 2 2 1 MFS/sugar transport protein zf-LITAF-like PF10601.9 KXS19454.1 - 0.17 12.1 1.4 0.64 10.3 0.5 2.5 1 1 0 1 1 1 0 LITAF-like zinc ribbon domain CAF1A PF12253.8 KXS19455.1 - 2.4 8.4 5.0 4.6 7.5 5.0 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 subunit A DNA_pol_phi PF04931.13 KXS19456.1 - 4.8 5.2 14.4 6.4 4.7 14.4 1.2 1 0 0 1 1 1 0 DNA polymerase phi Afi1 PF07792.12 KXS19456.1 - 7 7.1 10.5 6.4 7.3 6.1 2.2 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking NOA36 PF06524.12 KXS19456.1 - 8 5.7 10.7 16 4.7 10.7 1.5 1 0 0 1 1 1 0 NOA36 protein BSP_II PF05432.11 KXS19456.1 - 8.9 5.9 23.4 0.11 12.1 14.8 1.9 2 1 0 2 2 2 0 Bone sialoprotein II (BSP-II) Peptidase_M17 PF00883.21 KXS19457.1 - 5.9e-57 193.3 0.0 7.7e-57 192.9 0.0 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Cyt-b5 PF00173.28 KXS19459.1 - 2.8e-20 72.2 0.1 3.5e-20 71.9 0.1 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF3243 PF11588.8 KXS19459.1 - 0.15 12.4 0.0 9 6.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3243) p450 PF00067.22 KXS19461.1 - 2e-15 56.5 0.0 2.6e-15 56.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KXS19462.1 - 1.4e-21 76.8 0.0 2e-15 56.5 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 RtcR PF06956.11 KXS19462.1 - 0.11 11.9 0.0 0.57 9.6 0.0 2.0 2 0 0 2 2 2 0 Regulator of RNA terminal phosphate cyclase LPMO_10 PF03067.15 KXS19463.1 - 3.7e-08 34.2 0.1 1.5e-07 32.2 0.1 2.0 1 1 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Amidohydro_3 PF07969.11 KXS19464.1 - 1.1e-08 35.0 4.2 0.00095 18.7 0.1 2.8 1 1 1 2 2 2 2 Amidohydrolase family Orthopox_F14 PF06076.12 KXS19464.1 - 0.031 14.5 0.2 0.088 13.1 0.2 1.7 1 0 0 1 1 1 0 Orthopoxvirus F14 protein ARID PF01388.21 KXS19465.1 - 3e-09 37.4 0.0 7.4e-09 36.2 0.0 1.7 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain K_oxygenase PF13434.6 KXS19471.1 - 3.5e-09 36.3 0.0 7.2e-07 28.7 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KXS19471.1 - 9.9e-09 35.3 0.0 4e-08 33.4 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.19 KXS19471.1 - 5e-08 31.8 0.1 7.6e-06 24.6 0.3 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KXS19471.1 - 2.6e-06 26.9 0.0 1.2e-05 24.7 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXS19471.1 - 0.0024 17.5 0.6 0.36 10.4 0.4 2.7 1 1 1 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 KXS19471.1 - 0.0042 16.4 0.1 0.012 14.9 0.0 1.7 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 KXS19471.1 - 0.017 14.3 0.0 0.14 11.2 0.0 2.0 1 1 0 2 2 2 0 FAD binding domain Pyr_redox_3 PF13738.6 KXS19471.1 - 0.055 12.7 0.0 0.14 11.4 0.0 1.8 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DnaJ PF00226.31 KXS19472.1 - 2e-20 72.6 0.0 3.5e-20 71.9 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain Spore-coat_CotD PF11122.8 KXS19472.1 - 0.086 13.7 1.4 0.13 13.1 0.3 1.9 2 0 0 2 2 2 0 Inner spore coat protein D p450 PF00067.22 KXS19473.1 - 9.1e-81 271.9 0.0 1.2e-80 271.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Involucrin_N PF10583.9 KXS19473.1 - 0.16 12.6 0.0 0.29 11.7 0.0 1.4 1 0 0 1 1 1 0 Involucrin of squamous epithelia N-terminus COesterase PF00135.28 KXS19474.1 - 6.9e-83 279.2 0.0 1.4e-82 278.3 0.0 1.4 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXS19474.1 - 1.9e-06 27.9 0.0 1e-05 25.5 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Pkinase PF00069.25 KXS19476.1 - 9.2e-13 48.1 0.0 1e-12 48.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS19476.1 - 3.6e-07 29.7 0.0 4.5e-07 29.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXS19477.1 - 5.6e-13 48.9 0.0 6.6e-13 48.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS19477.1 - 4.9e-06 26.0 0.0 6e-06 25.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase SnoaL_2 PF12680.7 KXS19478.1 - 0.00079 20.0 0.0 0.0012 19.5 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 KXS19478.1 - 0.0054 16.5 0.0 0.0077 16.0 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase LEH PF07858.12 KXS19478.1 - 0.0081 16.3 0.1 0.0098 16.0 0.1 1.2 1 0 0 1 1 1 1 Limonene-1,2-epoxide hydrolase catalytic domain Macro PF01661.21 KXS19479.1 - 6e-38 129.5 0.1 9.6e-38 128.9 0.1 1.3 1 0 0 1 1 1 1 Macro domain ECH_1 PF00378.20 KXS19482.1 - 5.2e-39 134.1 0.0 1.2e-38 132.9 0.0 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXS19482.1 - 2.8e-21 76.4 0.6 3.1e-20 73.0 0.1 1.9 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase Carb_anhydrase PF00194.21 KXS19483.1 - 1.8e-32 112.9 0.1 4e-32 111.8 0.1 1.5 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase F-box-like PF12937.7 KXS19484.1 - 9.2e-09 35.1 0.2 3.2e-08 33.4 0.2 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXS19484.1 - 8.2e-05 22.4 0.8 0.00037 20.3 0.1 2.6 3 0 0 3 3 3 1 F-box domain F-box PF00646.33 KXS19485.1 - 0.0025 17.6 0.1 0.0069 16.2 0.1 1.7 1 0 0 1 1 1 1 F-box domain 4HBT_2 PF13279.6 KXS19486.1 - 6.3e-13 49.3 0.0 8.1e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.17 KXS19486.1 - 0.23 10.7 0.0 0.33 10.2 0.0 1.2 1 0 0 1 1 1 0 Acyl-ACP thioesterase SH3_9 PF14604.6 KXS19487.1 - 9.8e-15 54.1 0.1 5.7e-08 32.5 0.1 2.2 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 KXS19487.1 - 2.5e-11 43.0 0.0 3.3e-06 26.6 0.0 2.2 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 KXS19487.1 - 0.0031 17.2 0.0 0.063 13.0 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain SHD1 PF03983.12 KXS19488.1 - 4.3e-09 36.1 0.0 7.7e-06 25.6 0.0 2.3 1 1 1 2 2 2 2 SLA1 homology domain 1, SHD1 PQQ_2 PF13360.6 KXS19489.1 - 0.003 17.2 0.0 0.0035 17.0 0.0 1.1 1 0 0 1 1 1 1 PQQ-like domain PQQ_3 PF13570.6 KXS19489.1 - 0.007 16.8 0.4 0.033 14.7 0.4 1.9 2 0 0 2 2 2 1 PQQ-like domain PQQ PF01011.21 KXS19489.1 - 0.01 15.7 0.0 0.023 14.6 0.0 1.6 1 0 0 1 1 1 0 PQQ enzyme repeat Fungal_trans PF04082.18 KXS19491.1 - 2e-14 53.3 0.1 3.1e-14 52.6 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXS19491.1 - 1.5e-07 31.4 11.2 3.3e-07 30.3 11.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LRR_4 PF12799.7 KXS19492.1 - 3e-12 46.5 11.0 4.4e-07 30.1 3.7 2.5 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXS19492.1 - 2.2e-07 30.5 7.6 0.00024 20.8 0.1 2.2 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.33 KXS19492.1 - 3.4e-06 26.8 3.1 2.6 8.9 0.0 3.9 3 0 0 3 3 3 3 Leucine Rich Repeat LRR_9 PF14580.6 KXS19492.1 - 0.0021 17.6 0.3 0.0029 17.1 0.3 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_6 PF13516.6 KXS19492.1 - 0.082 13.0 8.3 3 8.1 2.2 3.3 3 0 0 3 3 3 0 Leucine Rich repeat MGC-24 PF05283.11 KXS19492.1 - 0.21 12.0 3.9 0.35 11.3 3.9 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin zf-C2H2_4 PF13894.6 KXS19493.1 - 1.4 9.9 4.9 0.38 11.7 0.7 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger SGL PF08450.12 KXS19495.1 - 0.00067 19.3 0.0 0.0038 16.9 0.0 2.1 2 0 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region PD40 PF07676.12 KXS19495.1 - 0.0098 15.8 4.4 0.16 11.9 0.2 3.6 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat Lactonase PF10282.9 KXS19495.1 - 0.1 11.8 0.0 25 4.0 0.0 3.1 3 0 0 3 3 3 0 Lactonase, 7-bladed beta-propeller Aldedh PF00171.22 KXS19496.1 - 2.2e-83 280.3 0.0 2.7e-83 280.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1155 PF06633.11 KXS19496.1 - 0.15 11.6 0.1 0.38 10.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1155) DUF4226 PF10774.9 KXS19497.1 - 0.02 15.2 1.6 0.046 14.0 1.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4226) HCMV_UL139 PF12507.8 KXS19497.1 - 0.088 13.2 3.5 0.18 12.2 3.5 1.4 1 0 0 1 1 1 0 Human Cytomegalovirus UL139 protein TPR_MLP1_2 PF07926.12 KXS19497.1 - 0.37 10.8 6.0 0.8 9.8 6.0 1.5 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Uso1_p115_C PF04871.13 KXS19497.1 - 0.67 10.3 6.6 2 8.8 6.5 1.8 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region HIP1_clath_bdg PF16515.5 KXS19497.1 - 1 10.0 6.3 79 4.0 6.7 2.5 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF3450 PF11932.8 KXS19497.1 - 2.4 7.4 6.1 18 4.5 3.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF3584 PF12128.8 KXS19497.1 - 2.6 5.4 6.7 3.7 4.9 6.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) BTB PF00651.31 KXS19499.1 - 5.9e-14 52.2 0.0 9e-14 51.7 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain Ank_2 PF12796.7 KXS19502.1 - 2.2e-06 28.2 0.0 0.0064 17.1 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXS19502.1 - 3.8e-05 24.1 0.1 0.052 14.1 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXS19502.1 - 4.8e-05 23.5 0.0 0.00012 22.3 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 KXS19502.1 - 0.025 15.0 0.0 5.7 7.6 0.0 2.3 1 1 1 2 2 2 0 Ankyrin repeat Ank_3 PF13606.6 KXS19502.1 - 0.068 13.8 0.0 3 8.7 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeat BTB PF00651.31 KXS19503.1 - 1.4e-07 31.7 0.0 2.4e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain F-box-like PF12937.7 KXS19504.1 - 0.00074 19.4 1.4 0.0012 18.7 0.0 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KXS19504.1 - 0.0011 18.8 2.9 0.0025 17.6 0.0 3.1 4 0 0 4 4 4 1 F-box domain Prismane PF03063.20 KXS19505.1 - 2.3e-124 415.9 0.0 3.5e-124 415.3 0.0 1.2 1 0 0 1 1 1 1 Prismane/CO dehydrogenase family FAD_binding_1 PF00667.20 KXS19505.1 - 2.5e-27 95.9 0.0 4.3e-27 95.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KXS19505.1 - 1.4e-24 87.0 0.1 2.5e-24 86.1 0.1 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 KXS19505.1 - 0.0041 17.7 0.0 0.02 15.5 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_NdrI PF07972.11 KXS19505.1 - 0.053 13.7 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 NrdI Flavodoxin like Euplotes_phero PF05842.11 KXS19505.1 - 0.13 12.8 0.7 1.4 9.4 0.0 2.2 2 0 0 2 2 2 0 Euplotes octocarinatus mating pheromone protein Glyco_hydro_26 PF02156.15 KXS19506.1 - 1.1e-06 28.3 6.5 7.7e-05 22.3 6.5 2.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 26 CwsA PF10814.8 KXS19506.1 - 0.065 13.4 0.3 0.38 10.9 0.0 2.2 1 1 1 2 2 2 0 Cell wall synthesis protein CwsA PX PF00787.24 KXS19507.1 - 0.007 16.3 0.0 0.39 10.7 0.0 2.7 1 1 0 1 1 1 1 PX domain Pkinase PF00069.25 KXS19508.1 - 2.9e-60 203.9 0.0 3.6e-60 203.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS19508.1 - 1.4e-28 99.9 0.0 1.9e-28 99.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXS19508.1 - 0.00014 20.8 0.1 0.00021 20.2 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KXS19508.1 - 0.00082 18.8 0.0 0.0012 18.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KXS19508.1 - 0.0011 18.4 0.0 0.0019 17.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXS19508.1 - 0.0031 17.5 0.3 0.0074 16.2 0.1 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family PTP_tm PF18861.1 KXS19509.1 - 0.39 10.7 1.1 0.41 10.6 0.1 1.5 2 0 0 2 2 2 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J CDPS PF16715.5 KXS19510.1 - 0.79 9.3 3.9 1.3 8.6 3.9 1.2 1 0 0 1 1 1 0 Cyclodipeptide synthase Gpr1_Fun34_YaaH PF01184.19 KXS19511.1 - 8.1e-20 71.3 20.6 1e-19 71.0 20.6 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Gpr1_Fun34_YaaH PF01184.19 KXS19512.1 - 7.7e-20 71.4 19.3 1e-19 71.0 19.3 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Gpr1_Fun34_YaaH PF01184.19 KXS19513.1 - 2.4e-20 73.0 19.3 3.2e-20 72.6 19.3 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Flavodoxin_5 PF12724.7 KXS19515.1 - 0.061 13.6 0.0 0.099 12.9 0.0 1.3 1 0 0 1 1 1 0 Flavodoxin domain Amidohydro_1 PF01979.20 KXS19516.1 - 3.1e-40 138.6 0.0 4.2e-40 138.1 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KXS19516.1 - 2.5e-12 47.0 1.3 5.2e-09 36.1 0.5 2.4 2 1 0 2 2 2 2 Amidohydrolase family A_deaminase PF00962.22 KXS19516.1 - 0.0055 16.1 0.0 0.0093 15.3 0.0 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase SH3_1 PF00018.28 KXS19517.1 - 1.4e-05 24.6 0.0 3.1e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 SH3 domain GIT_CC PF16559.5 KXS19517.1 - 0.0032 17.3 8.1 0.043 13.7 1.6 2.4 1 1 1 2 2 2 2 GIT coiled-coil Rho guanine nucleotide exchange factor Ank_2 PF12796.7 KXS19517.1 - 0.0041 17.7 0.0 0.012 16.2 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXS19517.1 - 0.0061 17.0 0.1 0.029 14.9 0.1 2.2 2 0 0 2 2 1 1 Ankyrin repeat Ank_4 PF13637.6 KXS19517.1 - 0.0083 16.7 0.0 0.033 14.8 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 KXS19517.1 - 0.0086 16.5 0.0 0.1 13.1 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeat bZIP_1 PF00170.21 KXS19517.1 - 0.014 15.5 6.8 0.23 11.6 0.2 2.5 2 0 0 2 2 2 0 bZIP transcription factor DUF5082 PF16888.5 KXS19517.1 - 0.017 15.4 3.4 0.017 15.4 3.4 1.6 2 0 0 2 2 1 0 Domain of unknown function (DUF5082) DUF4472 PF14739.6 KXS19517.1 - 0.074 13.8 6.7 0.11 13.2 5.9 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4472) Ank_5 PF13857.6 KXS19517.1 - 0.077 13.3 0.0 0.25 11.7 0.0 1.9 1 0 0 1 1 1 0 Ankyrin repeats (many copies) bZIP_2 PF07716.15 KXS19517.1 - 0.11 12.6 9.1 0.54 10.4 1.0 2.7 2 0 0 2 2 2 0 Basic region leucine zipper KASH_CCD PF14662.6 KXS19517.1 - 0.19 11.5 9.5 0.3 10.9 9.5 1.2 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Shugoshin_N PF07558.11 KXS19517.1 - 0.32 10.9 8.6 0.55 10.2 1.7 2.5 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region TSC22 PF01166.18 KXS19517.1 - 0.49 10.7 6.9 3.4 8.1 3.5 2.9 1 1 1 2 2 2 0 TSC-22/dip/bun family JIP_LZII PF16471.5 KXS19517.1 - 1.6 8.9 7.0 21 5.3 4.9 2.8 2 1 0 2 2 2 0 JNK-interacting protein leucine zipper II YabA PF06156.13 KXS19517.1 - 3.2 8.4 8.0 8.4 7.1 2.0 2.5 1 1 1 2 2 2 0 Initiation control protein YabA Seryl_tRNA_N PF02403.22 KXS19517.1 - 3.9 7.7 7.5 12 6.2 7.3 1.9 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain ZapB PF06005.12 KXS19517.1 - 5.3 7.5 12.2 7.7 7.0 5.4 2.6 1 1 1 2 2 2 0 Cell division protein ZapB HALZ PF02183.18 KXS19517.1 - 6.7 7.0 6.3 57 4.0 0.2 2.9 2 1 0 2 2 2 0 Homeobox associated leucine zipper DPPIV_N PF00930.21 KXS19518.1 - 2.5e-55 187.7 0.0 3.5e-55 187.2 0.0 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 KXS19518.1 - 6.6e-39 133.6 0.2 1.1e-38 132.9 0.2 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 KXS19518.1 - 5.6e-09 36.0 2.4 8.7e-07 28.8 1.5 2.3 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.8 KXS19518.1 - 0.00028 20.3 0.1 0.06 12.6 0.0 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KXS19518.1 - 0.0095 15.6 0.1 0.023 14.3 0.1 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold UPF0227 PF05728.12 KXS19518.1 - 0.024 14.6 0.0 0.051 13.5 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Abhydrolase_3 PF07859.13 KXS19518.1 - 0.086 12.7 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold DLH PF01738.18 KXS19518.1 - 0.11 12.1 0.0 0.24 10.9 0.0 1.5 1 1 0 1 1 1 0 Dienelactone hydrolase family BAAT_C PF08840.11 KXS19518.1 - 0.11 12.4 0.0 4.3 7.2 0.0 2.2 1 1 1 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Sod_Cu PF00080.20 KXS19519.1 - 2.4e-06 27.8 0.2 8.3e-05 22.8 0.2 2.2 1 1 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) HMA PF00403.26 KXS19519.1 - 0.013 15.9 0.0 0.033 14.6 0.0 1.7 1 0 0 1 1 1 0 Heavy-metal-associated domain Abhydrolase_1 PF00561.20 KXS19520.1 - 4.1e-16 59.4 0.0 2.1e-12 47.3 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXS19520.1 - 4.4e-10 40.5 2.4 6.2e-10 40.0 2.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXS19520.1 - 0.0018 17.6 0.0 0.019 14.3 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Kinesin PF00225.23 KXS19523.1 - 1.5e-80 270.6 0.0 1.7e-80 270.4 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KXS19523.1 - 1e-11 45.0 0.0 2.1e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding Inhibitor_I42 PF09394.10 KXS19524.1 - 5.6e-18 65.1 0.4 7.1e-18 64.8 0.4 1.1 1 0 0 1 1 1 1 Chagasin family peptidase inhibitor I42 GT87 PF09594.10 KXS19524.1 - 0.021 14.6 0.2 0.027 14.2 0.2 1.1 1 0 0 1 1 1 0 Glycosyltransferase family 87 Acetyltransf_1 PF00583.25 KXS19525.1 - 5.2e-18 65.4 0.0 6.5e-18 65.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXS19525.1 - 8.3e-17 61.3 0.0 1.1e-16 60.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXS19525.1 - 2.2e-14 53.6 0.0 3.4e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KXS19525.1 - 5.4e-07 29.7 0.1 6.6e-07 29.4 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KXS19525.1 - 8.9e-06 25.9 0.0 1.2e-05 25.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KXS19525.1 - 1.4e-05 25.2 0.0 2.3e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 KXS19525.1 - 0.00087 19.2 0.0 0.0016 18.4 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 KXS19525.1 - 0.002 18.8 0.0 0.0024 18.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.7 KXS19525.1 - 0.0093 16.1 0.1 0.014 15.5 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Ank_2 PF12796.7 KXS19527.1 - 0.00013 22.5 0.1 0.016 15.8 0.0 3.0 3 1 0 3 3 3 1 Ankyrin repeats (3 copies) SH3_2 PF07653.17 KXS19527.1 - 0.00084 19.0 0.0 0.003 17.2 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.6 KXS19527.1 - 0.0048 16.7 0.3 0.011 15.6 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain Ank_4 PF13637.6 KXS19527.1 - 0.02 15.4 0.0 0.22 12.2 0.0 2.6 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXS19527.1 - 0.023 15.0 0.1 0.15 12.4 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank PF00023.30 KXS19527.1 - 0.037 14.5 0.6 1.4 9.5 0.1 3.3 3 0 0 3 3 3 0 Ankyrin repeat Ank_3 PF13606.6 KXS19527.1 - 0.15 12.7 0.2 5 8.0 0.0 3.4 3 0 0 3 3 3 0 Ankyrin repeat FtsJ PF01728.19 KXS19528.1 - 9.2e-27 94.3 0.0 1.4e-26 93.7 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Lum_binding PF00677.17 KXS19529.1 - 1.1e-40 137.5 0.0 4.3e-20 71.5 0.4 2.3 2 0 0 2 2 2 2 Lumazine binding domain C2 PF00168.30 KXS19530.1 - 1.2e-13 51.2 0.0 2e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 C2 domain C2 PF00168.30 KXS19531.1 - 2.3e-52 175.6 0.1 6.5e-20 71.3 0.0 3.3 3 0 0 3 3 3 3 C2 domain DUF4381 PF14316.6 KXS19531.1 - 0.22 11.8 3.1 0.46 10.7 3.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) IstB_IS21_ATP PF08483.11 KXS19531.1 - 0.24 11.4 0.9 1.4 8.9 0.2 2.3 2 0 0 2 2 2 0 IstB-like ATP binding N-terminal Ribosomal_L4 PF00573.22 KXS19532.1 - 8.7e-43 146.2 3.1 1.3e-42 145.6 3.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 KXS19532.1 - 2.4e-27 94.8 4.5 2.8e-27 94.6 0.9 2.5 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain LAG1-DNAbind PF09271.11 KXS19533.1 - 8.1e-15 55.8 0.0 4e-14 53.5 0.0 2.1 2 1 0 2 2 2 1 LAG1, DNA binding BTD PF09270.10 KXS19533.1 - 3.4e-10 40.3 0.0 4.5e-07 30.2 0.1 2.9 2 1 0 2 2 2 2 Beta-trefoil DNA-binding domain TIG PF01833.24 KXS19534.1 - 0.15 12.2 0.0 0.21 11.7 0.0 1.2 1 0 0 1 1 1 0 IPT/TIG domain Acyltransferase PF01553.21 KXS19535.1 - 3.5e-25 88.2 0.0 4.8e-25 87.7 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase CRAL_TRIO PF00650.20 KXS19536.1 - 4.4e-21 75.3 0.0 6.5e-21 74.7 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KXS19536.1 - 6.3e-05 23.1 0.2 0.00039 20.6 0.0 2.4 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KXS19536.1 - 0.0005 20.2 0.0 0.00075 19.7 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain E1_dh PF00676.20 KXS19537.1 - 4.8e-116 386.9 0.1 6.3e-116 386.5 0.1 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 KXS19537.1 - 6.2e-05 22.8 0.5 0.00018 21.4 0.5 1.8 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.6 KXS19537.1 - 0.0001 21.6 0.0 0.00026 20.3 0.0 1.6 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase MT-A70 PF05063.14 KXS19538.1 - 1.6e-12 47.7 0.0 2.6e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 MT-A70 zf-C2H2 PF00096.26 KXS19539.1 - 5.9e-15 54.8 15.5 8.5e-05 22.8 3.9 3.2 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KXS19539.1 - 1.1e-11 44.5 9.5 2.3e-06 27.8 0.3 3.9 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KXS19539.1 - 1.4e-10 41.1 11.4 0.00057 20.5 0.3 3.3 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KXS19539.1 - 0.00015 22.0 2.1 0.00052 20.3 2.1 1.7 1 1 1 2 2 2 1 C2H2-type zinc ribbon Ogr_Delta PF04606.12 KXS19539.1 - 0.00064 19.7 4.1 0.011 15.7 1.5 2.7 2 1 0 2 2 2 1 Ogr/Delta-like zinc finger zf-met PF12874.7 KXS19539.1 - 0.0021 18.4 4.6 0.075 13.4 1.3 3.3 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 KXS19539.1 - 0.0043 16.8 9.2 0.043 13.6 0.1 3.0 3 0 0 3 3 3 2 zinc-finger C2H2-type Zn-ribbon_8 PF09723.10 KXS19539.1 - 0.012 15.8 7.8 1.2 9.3 1.8 3.0 1 1 2 3 3 3 0 Zinc ribbon domain zf_ZIC PF18366.1 KXS19539.1 - 0.015 15.4 3.4 0.35 11.0 0.3 3.0 2 1 1 3 3 3 0 Zic proteins zinc finger domain zf-C2H2_jaz PF12171.8 KXS19539.1 - 0.031 14.5 0.4 0.031 14.5 0.4 2.2 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-trcl PF13451.6 KXS19539.1 - 0.087 12.7 3.2 1.1 9.2 0.4 2.9 3 0 0 3 3 3 0 Probable zinc-ribbon domain zf-CCHC_2 PF13696.6 KXS19539.1 - 0.1 12.4 2.1 0.1 12.4 2.1 3.3 4 0 0 4 4 4 0 Zinc knuckle zf-C2H2_3rep PF18868.1 KXS19539.1 - 0.13 13.0 5.3 17 6.1 0.3 3.0 1 1 2 3 3 3 0 Zinc finger C2H2-type, 3 repeats zf-LYAR PF08790.11 KXS19539.1 - 0.42 10.5 5.2 0.54 10.2 1.4 2.7 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger FYVE PF01363.21 KXS19539.1 - 0.51 10.5 9.4 2.3 8.4 1.7 2.3 2 0 0 2 2 2 0 FYVE zinc finger C1_4 PF07975.12 KXS19539.1 - 0.57 10.5 5.3 9.6 6.5 1.0 2.6 1 1 0 2 2 2 0 TFIIH C1-like domain PriA_CRR PF18319.1 KXS19539.1 - 1.5 8.9 8.7 1.5 8.9 2.3 3.1 2 1 1 3 3 3 0 PriA DNA helicase Cys-rich region (CRR) domain zf-C2H2_6 PF13912.6 KXS19539.1 - 4.6 7.3 14.4 0.61 10.2 2.6 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger Zn_Tnp_IS1595 PF12760.7 KXS19539.1 - 4.9 7.2 9.9 8 6.5 0.3 2.8 2 1 1 3 3 3 0 Transposase zinc-ribbon domain Tcf25 PF04910.14 KXS19540.1 - 2.3e-57 194.6 0.0 6.6e-32 110.9 0.1 2.2 2 0 0 2 2 2 2 Transcriptional repressor TCF25 TPR_12 PF13424.6 KXS19540.1 - 0.00014 22.0 1.6 0.00094 19.4 0.2 3.2 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 KXS19540.1 - 0.00028 20.7 0.1 0.00095 19.0 0.1 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 KXS19540.1 - 0.008 16.9 0.1 0.083 13.8 0.1 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat CTD_bind PF04818.13 KXS19541.1 - 1.6e-05 25.7 0.0 4.7e-05 24.1 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase II-binding domain. CFIA_Pcf11 PF11526.8 KXS19541.1 - 0.0061 17.0 0.0 0.012 16.0 0.0 1.5 1 0 0 1 1 1 1 Subunit of cleavage factor IA Pcf11 zf_UBZ PF18439.1 KXS19541.1 - 6.3 6.5 8.9 6 6.5 4.9 2.6 2 1 0 2 2 2 0 Ubiquitin-Binding Zinc Finger PRP38 PF03371.15 KXS19542.1 - 5e-41 140.4 0.6 2.2e-40 138.4 0.6 1.8 1 1 0 1 1 1 1 PRP38 family NDUFA12 PF05071.16 KXS19543.1 - 4.1e-17 62.8 4.2 5.4e-17 62.4 4.2 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 SH3_9 PF14604.6 KXS19544.1 - 4.1e-06 26.5 0.1 7.2e-06 25.8 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXS19544.1 - 2.5e-05 23.8 0.0 3.9e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 SH3 domain DUF4190 PF13828.6 KXS19544.1 - 0.0045 16.7 0.7 0.014 15.1 0.3 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4190) zf-H2C2_2 PF13465.6 KXS19545.1 - 0.0038 17.6 0.5 0.0038 17.6 0.5 3.8 4 0 0 4 4 4 2 Zinc-finger double domain DUF429 PF04250.13 KXS19545.1 - 0.093 12.5 0.2 0.17 11.7 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF429) Actin_micro PF17003.5 KXS19545.1 - 0.57 9.3 3.4 0.22 10.6 1.1 1.5 1 1 0 1 1 1 0 Putative actin-like family Ribosomal_L4 PF00573.22 KXS19546.1 - 1.7e-54 184.5 2.2 2.4e-54 183.9 2.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ras PF00071.22 KXS19547.1 - 8.3e-57 191.3 0.0 9.7e-57 191.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXS19547.1 - 5.4e-33 113.7 0.0 8e-33 113.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXS19547.1 - 1.8e-13 50.3 0.0 2.1e-13 50.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KXS19547.1 - 1.2e-07 31.8 0.0 1.8e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KXS19547.1 - 1.2e-06 28.1 0.0 1.4e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KXS19547.1 - 5.5e-06 26.1 0.0 0.00021 20.9 0.0 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KXS19547.1 - 0.00014 21.8 0.0 0.0023 17.8 0.1 2.2 1 1 0 2 2 2 1 RsgA GTPase SRPRB PF09439.10 KXS19547.1 - 0.00062 19.2 0.0 0.0009 18.7 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 KXS19547.1 - 0.0011 19.4 0.0 0.0017 18.8 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain cobW PF02492.19 KXS19547.1 - 0.0015 18.1 0.0 0.0043 16.7 0.0 1.7 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Septin PF00735.18 KXS19547.1 - 0.0027 17.0 0.1 0.011 15.1 0.0 1.8 2 0 0 2 2 2 1 Septin ATP_bind_1 PF03029.17 KXS19547.1 - 0.0046 16.8 0.1 0.42 10.4 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein PduV-EutP PF10662.9 KXS19547.1 - 0.0055 16.5 0.0 0.084 12.6 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation ATPase_2 PF01637.18 KXS19547.1 - 0.0083 16.1 0.0 0.012 15.5 0.0 1.2 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 KXS19547.1 - 0.012 15.9 0.0 0.026 14.8 0.0 1.6 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.6 KXS19547.1 - 0.013 15.2 0.0 0.025 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 KXS19547.1 - 0.016 14.7 0.0 0.023 14.1 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein AAA_7 PF12775.7 KXS19547.1 - 0.018 14.5 0.0 0.028 13.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region NACHT PF05729.12 KXS19547.1 - 0.026 14.4 0.0 0.041 13.8 0.0 1.3 1 0 0 1 1 1 0 NACHT domain NTPase_1 PF03266.15 KXS19547.1 - 0.044 13.7 0.0 0.074 13.0 0.0 1.4 1 0 0 1 1 1 0 NTPase G-alpha PF00503.20 KXS19547.1 - 0.073 12.2 0.1 0.17 11.0 0.1 1.5 1 1 1 2 2 2 0 G-protein alpha subunit DAP3 PF10236.9 KXS19547.1 - 0.077 12.1 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 ABC_tran PF00005.27 KXS19547.1 - 0.08 13.5 0.1 0.086 13.4 0.1 1.5 1 1 0 1 1 1 0 ABC transporter PRK PF00485.18 KXS19547.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family RNA_helicase PF00910.22 KXS19547.1 - 0.12 12.8 0.0 0.21 12.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_5 PF07728.14 KXS19547.1 - 0.14 12.2 0.0 0.37 10.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 KXS19547.1 - 0.15 11.2 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain Rif1_N PF12231.8 KXS19548.1 - 2.8e-23 82.5 0.0 2.7e-22 79.3 0.0 1.9 1 1 0 1 1 1 1 Rap1-interacting factor 1 N terminal HEAT_EZ PF13513.6 KXS19548.1 - 0.058 13.9 0.3 0.27 11.8 0.1 2.3 2 0 0 2 2 2 0 HEAT-like repeat CAP_GLY PF01302.25 KXS19550.1 - 1.5e-22 79.4 0.2 2.2e-22 78.8 0.2 1.3 1 0 0 1 1 1 1 CAP-Gly domain EF-hand_6 PF13405.6 KXS19550.1 - 0.015 15.2 0.1 0.071 13.1 0.1 2.1 2 0 0 2 2 2 0 EF-hand domain EF-hand_1 PF00036.32 KXS19550.1 - 0.057 13.0 0.4 0.16 11.6 0.0 2.0 2 0 0 2 2 2 0 EF hand EF-hand_7 PF13499.6 KXS19550.1 - 0.091 13.2 0.0 0.29 11.6 0.0 1.8 2 0 0 2 2 2 0 EF-hand domain pair MAGE PF01454.19 KXS19551.1 - 2.2e-44 151.7 0.0 2.2e-44 151.7 0.0 1.6 2 0 0 2 2 2 1 MAGE family TFIIF_alpha PF05793.12 KXS19551.1 - 4.8 5.7 21.8 7 5.1 21.8 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Tubulin PF00091.25 KXS19552.1 - 2.9e-70 236.5 0.0 4.6e-70 235.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KXS19552.1 - 7.7e-45 152.1 0.2 1.7e-44 151.0 0.0 1.7 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 KXS19552.1 - 0.00048 20.4 0.0 0.0018 18.6 0.0 2.0 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 KXS19552.1 - 0.026 14.2 0.2 0.082 12.6 0.0 2.0 2 0 0 2 2 2 0 Tubulin domain Ecl1 PF12855.7 KXS19553.1 - 0.0024 19.1 28.8 0.27 12.4 28.8 2.3 1 1 0 1 1 1 1 ECL1/2/3 zinc binding proteins DUF2116 PF09889.9 KXS19553.1 - 0.06 13.3 1.8 0.06 13.3 1.8 1.8 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Peptidase_M41 PF01434.18 KXS19554.1 - 1.1e-63 214.5 0.2 1.7e-63 213.9 0.2 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 KXS19554.1 - 9.2e-44 149.1 0.0 2.2e-43 147.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KXS19554.1 - 3.2e-12 46.0 0.2 7.6e-12 44.8 0.2 1.6 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 KXS19554.1 - 1.2e-07 32.1 0.0 5.9e-07 29.8 0.0 2.2 1 1 0 1 1 1 1 FtsH Extracellular AAA_16 PF13191.6 KXS19554.1 - 0.00029 21.3 0.2 0.06 13.7 0.1 3.3 2 1 0 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 KXS19554.1 - 0.00056 19.9 0.0 0.017 15.1 0.0 2.9 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KXS19554.1 - 0.0019 17.9 0.1 0.009 15.8 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 KXS19554.1 - 0.0044 16.3 0.1 0.0093 15.2 0.1 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 KXS19554.1 - 0.0094 16.2 0.0 0.7 10.2 0.1 2.7 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.14 KXS19554.1 - 0.014 15.5 0.0 0.064 13.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) AAA_17 PF13207.6 KXS19554.1 - 0.02 15.3 0.4 0.11 12.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 KXS19554.1 - 0.088 12.5 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_28 PF13521.6 KXS19554.1 - 0.21 11.8 0.9 0.48 10.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain Ank_2 PF12796.7 KXS19556.1 - 2.8e-16 59.9 0.7 1.9e-07 31.5 0.1 3.3 2 1 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXS19556.1 - 3.9e-12 45.2 1.9 0.51 11.1 0.0 6.6 7 0 0 7 7 7 4 Ankyrin repeat Ank_4 PF13637.6 KXS19556.1 - 3.3e-09 37.1 1.3 0.48 11.1 0.0 5.8 5 1 1 6 6 6 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXS19556.1 - 1.1e-06 28.8 6.8 0.11 12.8 0.8 4.8 4 1 3 7 7 7 2 Ankyrin repeats (many copies) Ank PF00023.30 KXS19556.1 - 4.7e-06 26.8 7.9 0.47 11.0 0.1 6.1 6 1 1 7 7 7 2 Ankyrin repeat PCI PF01399.27 KXS19558.1 - 2.4e-16 60.1 0.0 1e-15 58.1 0.0 2.1 2 1 0 2 2 2 1 PCI domain CSN4_RPN5_eIF3a PF18420.1 KXS19558.1 - 1.3e-07 31.6 0.0 3.1e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 CSN4/RPN5/eIF3a helix turn helix domain SIR2 PF02146.17 KXS19559.1 - 2.2e-16 60.3 1.0 1e-11 45.1 0.0 2.5 2 1 0 2 2 2 2 Sir2 family TPP_enzyme_M PF00205.22 KXS19559.1 - 0.16 11.7 0.0 12 5.6 0.0 2.6 3 0 0 3 3 3 0 Thiamine pyrophosphate enzyme, central domain p450 PF00067.22 KXS19560.1 - 8.5e-78 262.1 0.0 1.1e-77 261.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AAA_35 PF14516.6 KXS19560.1 - 0.022 13.6 0.1 0.046 12.6 0.0 1.5 1 1 0 1 1 1 0 AAA-like domain DUF465 PF04325.13 KXS19560.1 - 0.16 12.0 0.1 0.33 11.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF465) Mito_carr PF00153.27 KXS19561.1 - 4.7e-63 209.2 3.9 2.6e-20 72.2 0.0 4.1 4 0 0 4 4 4 4 Mitochondrial carrier protein PRP38_assoc PF12871.7 KXS19562.1 - 0.0032 18.1 16.8 0.0032 18.1 16.8 2.4 2 0 0 2 2 2 1 Pre-mRNA-splicing factor 38-associated hydrophilic C-term 3Beta_HSD PF01073.19 KXS19565.1 - 1e-45 155.9 0.0 1.3e-45 155.6 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KXS19565.1 - 1.2e-22 80.6 0.0 1.7e-22 80.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KXS19565.1 - 1.9e-10 41.0 0.0 2.7e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KXS19565.1 - 3.2e-10 39.6 0.0 2.2e-07 30.3 0.0 2.2 1 1 1 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 KXS19565.1 - 2.5e-08 33.4 0.0 4.3e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KXS19565.1 - 1.6e-06 27.5 0.1 0.00015 21.0 0.0 3.0 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KXS19565.1 - 3.8e-06 26.5 0.0 0.00013 21.4 0.0 2.4 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 KXS19565.1 - 0.015 14.9 0.0 0.03 13.9 0.0 1.5 1 1 0 1 1 1 0 NmrA-like family MMR_HSR1_Xtn PF16897.5 KXS19566.1 - 8.3e-43 144.7 0.1 1.9e-42 143.6 0.1 1.6 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 KXS19566.1 - 4.2e-24 84.3 0.0 9e-24 83.3 0.0 1.6 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 KXS19566.1 - 3e-20 72.4 0.0 5.8e-20 71.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KXS19566.1 - 1.8e-11 43.8 0.1 8.1e-11 41.7 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B MeaB PF03308.16 KXS19566.1 - 0.00077 18.5 0.9 0.0074 15.3 0.3 2.2 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB GTP_EFTU PF00009.27 KXS19566.1 - 0.011 15.3 0.1 7.3 6.1 0.0 3.4 2 2 1 3 3 3 0 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 KXS19566.1 - 0.022 14.8 0.2 6.5 6.8 0.0 2.4 1 1 1 2 2 2 0 Dynamin family Beta-lactamase PF00144.24 KXS19567.1 - 2.2e-54 184.9 0.1 2.8e-54 184.6 0.1 1.1 1 0 0 1 1 1 1 Beta-lactamase CDC73_C PF05179.14 KXS19568.1 - 2.8e-50 170.1 0.7 4.4e-50 169.4 0.7 1.2 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal CDC73_N PF16050.5 KXS19568.1 - 0.00087 18.7 0.0 0.15 11.3 0.0 2.3 1 1 0 2 2 2 2 Paf1 complex subunit CDC73 N-terminal SOG2 PF10428.9 KXS19568.1 - 0.9 8.7 5.1 1.7 7.7 5.1 1.5 1 0 0 1 1 1 0 RAM signalling pathway protein RAP1 PF07218.11 KXS19569.1 - 8.3 4.5 6.8 13 3.9 6.8 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Sel1 PF08238.12 KXS19570.1 - 3.7e-51 170.4 15.8 5.7e-08 33.2 0.1 8.5 9 0 0 9 9 9 7 Sel1 repeat Pkinase PF00069.25 KXS19570.1 - 2.1e-21 76.5 0.0 3e-21 76.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS19570.1 - 1.1e-14 54.4 0.0 1.7e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXS19570.1 - 0.0031 16.9 0.0 0.015 14.7 0.0 1.9 1 1 0 1 1 1 1 Kinase-like TPR_7 PF13176.6 KXS19570.1 - 0.055 13.5 0.1 0.23 11.6 0.1 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.6 KXS19570.1 - 0.072 13.8 0.0 7.1 7.5 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Zds_C PF08632.10 KXS19572.1 - 3.8e-12 45.8 1.1 6.8e-12 44.9 1.1 1.4 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term Ring_hydroxyl_A PF00848.19 KXS19573.1 - 2.5e-28 99.5 0.1 5.2e-27 95.2 0.1 2.3 1 1 0 1 1 1 1 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.26 KXS19573.1 - 8e-16 57.8 0.0 1.5e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain PEPCK_N PF17297.2 KXS19573.1 - 0.0065 16.1 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase N-terminal domain YdiH PF15930.5 KXS19573.1 - 0.057 13.6 0.2 0.15 12.3 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function DUF1242 PF06842.12 KXS19574.1 - 5.6e-15 54.9 2.1 7.7e-15 54.4 2.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) NUDIX PF00293.28 KXS19575.1 - 5.6e-12 45.8 0.4 3.2e-11 43.4 0.1 2.6 2 0 0 2 2 2 1 NUDIX domain HAUS-augmin3 PF14932.6 KXS19575.1 - 0.0036 16.9 1.5 0.0036 16.9 1.5 7.4 3 1 4 7 7 7 2 HAUS augmin-like complex subunit 3 SOGA PF11365.8 KXS19575.1 - 0.005 17.9 5.1 0.005 17.9 5.1 9.1 3 1 5 9 9 9 1 Protein SOGA ATG16 PF08614.11 KXS19575.1 - 0.01 16.1 1.5 0.01 16.1 1.5 7.7 1 1 8 9 9 9 0 Autophagy protein 16 (ATG16) HIP1_clath_bdg PF16515.5 KXS19575.1 - 0.025 15.2 1.6 0.025 15.2 1.6 9.6 3 2 6 9 9 9 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Osmo_CC PF08946.10 KXS19575.1 - 1.1 9.5 5.8 1.6 9.0 0.5 3.9 3 0 0 3 3 3 0 Osmosensory transporter coiled coil HALZ PF02183.18 KXS19575.1 - 5.7 7.3 37.9 2.3 8.5 1.6 7.7 6 1 0 6 6 6 0 Homeobox associated leucine zipper IQ PF00612.27 KXS19576.1 - 9.3e-08 31.2 9.8 0.0025 17.4 0.4 3.8 3 0 0 3 3 3 3 IQ calmodulin-binding motif DUF2870 PF11069.8 KXS19576.1 - 0.87 10.0 6.0 0.16 12.4 1.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) Mito_carr PF00153.27 KXS19577.1 - 8.7e-54 179.4 4.7 8.9e-19 67.2 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF2623 PF11115.8 KXS19577.1 - 0.032 14.3 0.0 0.077 13.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2623) PsaX PF08078.12 KXS19579.1 - 0.033 14.2 0.1 0.056 13.4 0.1 1.3 1 0 0 1 1 1 0 PsaX family Mucin PF01456.17 KXS19579.1 - 0.16 12.0 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein TFIIA_gamma_N PF02268.16 KXS19580.1 - 2e-20 72.5 0.1 3e-20 72.0 0.1 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TFIIA_gamma_C PF02751.14 KXS19580.1 - 3.5e-11 43.0 0.1 5.3e-11 42.5 0.1 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit Scytalone_dh PF02982.14 KXS19580.1 - 0.0017 18.2 0.0 0.0018 18.1 0.0 1.1 1 0 0 1 1 1 1 Scytalone dehydratase Complex1_LYR PF05347.15 KXS19581.1 - 7.9e-08 32.2 0.3 1.4e-07 31.4 0.0 1.6 2 0 0 2 2 2 1 Complex 1 protein (LYR family) SIP1 PF04938.12 KXS19582.1 - 1e-18 67.9 0.0 3.1e-09 36.9 0.0 2.3 2 0 0 2 2 2 2 Survival motor neuron (SMN) interacting protein 1 (SIP1) UPF0029 PF01205.19 KXS19582.1 - 0.027 14.8 0.0 0.07 13.5 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein family UPF0029 Peptidase_M16_C PF05193.21 KXS19583.1 - 3.2e-41 141.4 0.0 5e-41 140.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KXS19583.1 - 3.9e-35 121.0 0.0 7.7e-35 120.1 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_MA_2 PF13485.6 KXS19583.1 - 0.19 11.4 0.0 0.69 9.5 0.0 1.9 2 1 0 2 2 2 0 Peptidase MA superfamily DUF382 PF04037.13 KXS19584.1 - 2.2e-60 202.4 2.5 2.2e-60 202.4 2.5 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF382) PSP PF04046.16 KXS19584.1 - 4.4e-21 74.5 7.1 1e-20 73.3 7.1 1.7 1 0 0 1 1 1 1 PSP RasGEF PF00617.19 KXS19585.1 - 1.6e-14 54.5 0.0 2.8e-14 53.7 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain RhoGAP PF00620.27 KXS19586.1 - 7.3e-41 139.5 0.0 1.5e-40 138.5 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.23 KXS19586.1 - 6.7e-08 32.7 0.4 6.7e-08 32.7 0.4 2.0 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain T3SSipB PF16535.5 KXS19586.1 - 0.15 12.5 6.0 0.49 10.8 6.0 1.9 1 0 0 1 1 1 0 Type III cell invasion protein SipB SMG1_N PF17229.2 KXS19586.1 - 0.23 12.2 1.1 0.56 10.9 1.1 1.7 1 0 0 1 1 1 0 Serine/threonine-protein kinase SMG1 N-terminal DLP_helical PF18709.1 KXS19586.1 - 0.5 9.5 6.2 0.63 9.2 1.5 2.8 3 0 0 3 3 3 0 Dynamin-like helical domain HR1 PF02185.16 KXS19586.1 - 3.6 7.8 8.5 1.1 9.5 3.4 2.5 2 0 0 2 2 2 0 Hr1 repeat Phage_GP20 PF06810.11 KXS19586.1 - 6.4 6.6 8.7 1.9 8.3 4.2 2.2 2 1 0 2 2 2 0 Phage minor structural protein GP20 Utp11 PF03998.13 KXS19587.1 - 1e-79 268.0 12.1 1.2e-79 267.8 12.1 1.0 1 0 0 1 1 1 1 Utp11 protein Kelch_4 PF13418.6 KXS19588.1 - 3.6e-22 78.1 6.3 2.8e-07 30.4 0.1 4.8 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_3 PF13415.6 KXS19588.1 - 1.4e-18 66.7 2.9 0.00045 20.4 0.0 5.8 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_6 PF13964.6 KXS19588.1 - 5e-16 58.3 2.6 0.0034 17.6 0.0 5.0 5 0 0 5 5 5 4 Kelch motif Kelch_5 PF13854.6 KXS19588.1 - 3.8e-15 55.5 0.9 5.6e-05 23.0 0.0 4.5 5 0 0 5 5 5 3 Kelch motif Kelch_1 PF01344.25 KXS19588.1 - 9.8e-09 34.7 5.4 0.006 16.2 0.2 4.5 5 0 0 5 5 5 3 Kelch motif Kelch_2 PF07646.15 KXS19588.1 - 1.6e-07 31.0 7.4 0.44 10.6 0.2 4.4 4 0 0 4 4 4 3 Kelch motif Ribosomal_S3_C PF00189.20 KXS19589.1 - 0.01 16.3 0.0 0.017 15.6 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein S3, C-terminal domain MAM33 PF02330.16 KXS19590.1 - 2.4e-55 187.8 4.5 3.1e-55 187.4 4.5 1.1 1 0 0 1 1 1 1 Mitochondrial glycoprotein Vps51 PF08700.11 KXS19591.1 - 0.045 13.8 0.0 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 Vps51/Vps67 SNRNP27 PF08648.12 KXS19592.1 - 1.9e-29 101.5 0.4 3.2e-29 100.8 0.4 1.4 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins PRCC PF10253.9 KXS19594.1 - 1.2e-14 55.7 21.3 1.5e-14 55.3 19.3 2.1 1 1 1 2 2 2 1 Mitotic checkpoint regulator, MAD2B-interacting ABC_tran PF00005.27 KXS19595.1 - 2.4e-47 160.9 0.1 3.4e-23 82.7 0.0 2.3 2 0 0 2 2 2 2 ABC transporter Forkhead PF00250.18 KXS19595.1 - 1.3e-29 102.3 0.0 2.5e-29 101.4 0.0 1.4 1 0 0 1 1 1 1 Forkhead domain ABC2_membrane PF01061.24 KXS19595.1 - 2.7e-21 76.0 33.6 1.5e-17 63.7 4.4 3.6 3 1 1 4 4 3 3 ABC-2 type transporter AAA_21 PF13304.6 KXS19595.1 - 1.9e-15 57.4 1.2 0.00016 21.6 0.0 4.3 3 1 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KXS19595.1 - 1.8e-09 38.4 0.5 0.00013 22.5 0.1 2.3 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.19 KXS19595.1 - 4.5e-07 29.5 0.0 0.032 13.7 0.0 2.9 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KXS19595.1 - 3.3e-06 27.1 0.4 0.026 14.4 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 KXS19595.1 - 5.2e-05 22.9 5.8 0.0011 18.6 0.1 3.2 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_22 PF13401.6 KXS19595.1 - 0.00049 20.4 2.3 0.016 15.5 0.1 3.1 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KXS19595.1 - 0.00053 20.4 0.2 0.47 10.8 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain Malic_M PF03949.15 KXS19595.1 - 0.0034 16.7 0.0 0.82 8.9 0.0 2.2 2 0 0 2 2 2 1 Malic enzyme, NAD binding domain MMR_HSR1 PF01926.23 KXS19595.1 - 0.0047 17.0 0.8 0.87 9.7 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF2791 PF10923.8 KXS19595.1 - 0.039 12.8 0.1 4.1 6.2 0.0 2.7 3 0 0 3 3 3 0 P-loop Domain of unknown function (DUF2791) AAA_15 PF13175.6 KXS19595.1 - 0.051 13.3 0.9 8.8 5.9 0.2 2.4 2 0 0 2 2 2 0 AAA ATPase domain PRK PF00485.18 KXS19595.1 - 0.066 12.9 1.3 0.78 9.5 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_30 PF13604.6 KXS19595.1 - 0.13 12.0 1.4 4.7 6.9 0.1 2.4 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 KXS19595.1 - 0.28 11.4 0.8 16 5.7 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 KXS19595.1 - 0.47 10.0 2.3 4.3 6.9 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 KXS19595.1 - 0.8 9.6 2.3 11 5.9 0.3 2.5 2 0 0 2 2 2 0 NACHT domain AAA_28 PF13521.6 KXS19595.1 - 8.6 6.6 5.3 30 4.8 0.2 2.5 2 0 0 2 2 2 0 AAA domain Ribosomal_S10 PF00338.22 KXS19596.1 - 3.1e-29 101.1 0.2 4.1e-29 100.7 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Ribosomal_S21 PF01165.20 KXS19597.1 - 1.4e-09 37.5 4.0 2.5e-09 36.7 4.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S21 PP2C PF00481.21 KXS19598.1 - 5.4e-69 232.7 0.0 6.3e-69 232.5 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C GH131_N PF18271.1 KXS19599.1 - 3.5e-47 161.3 0.1 1e-46 159.7 0.1 1.7 1 1 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain ECH_1 PF00378.20 KXS19600.1 - 3.5e-47 160.8 0.0 4.5e-47 160.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXS19600.1 - 1e-23 84.4 0.2 1.6e-21 77.1 0.1 2.1 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Peptidase_M76 PF09768.9 KXS19600.1 - 0.093 12.5 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Peptidase M76 family Peptidase_S24 PF00717.23 KXS19601.1 - 9.9e-09 35.0 0.0 6.7e-08 32.4 0.0 1.9 1 1 1 2 2 2 1 Peptidase S24-like Peptidase_S26 PF10502.9 KXS19601.1 - 4.4e-07 29.8 0.1 3.6e-05 23.6 0.0 2.5 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 RRM_1 PF00076.22 KXS19602.1 - 6.8e-14 51.4 0.0 1.3e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pinin_SDK_memA PF04696.13 KXS19602.1 - 0.16 12.0 10.4 0.31 11.1 10.4 1.4 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region ECM1 PF05782.11 KXS19602.1 - 1.4 7.7 4.2 2 7.3 4.2 1.1 1 0 0 1 1 1 0 Extracellular matrix protein 1 (ECM1) DUF5427 PF10310.9 KXS19602.1 - 1.9 7.4 7.9 2.9 6.8 7.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5427) ANAPC4_WD40 PF12894.7 KXS19603.1 - 0.0064 16.8 0.1 0.39 11.0 0.0 2.4 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain La PF05383.17 KXS19605.1 - 1.1e-12 47.8 0.0 1.8e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 La domain WAC_Acf1_DNA_bd PF10537.9 KXS19606.1 - 1.7e-24 86.3 0.7 3.2e-24 85.4 0.7 1.5 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal DDT PF02791.17 KXS19606.1 - 1e-10 41.8 0.0 2e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 DDT domain HEAT_EZ PF13513.6 KXS19608.1 - 0.0015 19.0 0.2 2 9.0 0.1 3.3 2 0 0 2 2 2 2 HEAT-like repeat HEAT_2 PF13646.6 KXS19608.1 - 0.029 14.8 0.7 0.77 10.2 0.1 3.6 2 1 1 3 3 3 0 HEAT repeats HEAT PF02985.22 KXS19608.1 - 0.24 11.7 4.4 0.55 10.6 0.1 3.6 4 0 0 4 4 4 0 HEAT repeat KH_1 PF00013.29 KXS19610.1 - 8.4e-44 147.3 11.8 3.5e-16 58.8 0.2 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 KXS19610.1 - 1.7e-11 43.8 5.5 0.00012 21.8 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 KXS19610.1 - 8.9e-08 31.9 1.8 0.26 11.2 0.1 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 KXS19610.1 - 2.6e-07 30.6 4.7 0.014 15.4 0.0 3.4 3 0 0 3 3 3 3 NusA-like KH domain ThiP_synth PF10120.9 KXS19610.1 - 0.066 12.8 0.1 0.12 12.0 0.1 1.4 1 0 0 1 1 1 0 Thiamine-phosphate synthase Aldedh PF00171.22 KXS19612.1 - 1.9e-168 560.8 0.5 7.9e-168 558.7 0.5 1.7 1 1 0 1 1 1 1 Aldehyde dehydrogenase family WD40 PF00400.32 KXS19613.1 - 4.7e-18 65.2 10.1 8.4e-08 32.8 1.6 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXS19613.1 - 0.001 19.3 0.0 0.63 10.4 0.0 3.2 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Pkinase PF00069.25 KXS19614.1 - 4.8e-43 147.4 0.0 6.3e-43 147.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS19614.1 - 9.6e-20 70.9 0.0 1.4e-19 70.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXS19614.1 - 9.5e-06 25.1 0.0 2e-05 24.1 0.0 1.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KXS19614.1 - 4.3e-05 23.5 0.4 0.00011 22.2 0.4 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KXS19614.1 - 0.0003 19.8 0.2 0.0004 19.4 0.2 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KXS19614.1 - 0.00032 20.1 1.2 0.00053 19.4 1.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH_6_hur PF04655.14 KXS19614.1 - 0.021 14.2 0.6 0.12 11.7 0.0 2.1 2 0 0 2 2 2 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase Pkinase_fungal PF17667.1 KXS19614.1 - 0.021 13.6 0.2 0.033 13.0 0.2 1.2 1 0 0 1 1 1 0 Fungal protein kinase Choline_kinase PF01633.20 KXS19614.1 - 0.081 12.5 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase PF00069.25 KXS19615.1 - 6.6e-44 150.3 0.0 8.8e-44 149.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS19615.1 - 1.1e-19 70.8 0.0 1.5e-19 70.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXS19615.1 - 1.6e-05 24.9 0.4 6.4e-05 23.0 0.4 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KXS19615.1 - 0.0011 18.4 0.0 0.0017 17.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KXS19615.1 - 0.0014 17.6 0.2 0.0021 17.1 0.2 1.1 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 KXS19615.1 - 0.0017 18.0 0.0 0.0027 17.3 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 KXS19615.1 - 0.0044 16.4 0.2 0.0071 15.7 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KXS19616.1 - 1.2e-42 146.2 0.0 1.7e-42 145.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS19616.1 - 6.1e-22 78.1 0.0 8.4e-22 77.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KXS19616.1 - 0.00011 21.7 0.1 0.00017 21.1 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KXS19616.1 - 0.00016 21.1 0.0 0.00045 19.6 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 KXS19616.1 - 0.00025 21.0 0.3 0.0042 17.0 0.3 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXS19616.1 - 0.00077 18.4 0.0 0.0013 17.5 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 KXS19616.1 - 0.028 13.4 0.2 0.045 12.7 0.2 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Choline_kinase PF01633.20 KXS19616.1 - 0.12 12.0 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase dCMP_cyt_deam_1 PF00383.23 KXS19617.1 - 7.5e-09 35.4 0.0 1e-08 35.0 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KXS19617.1 - 0.0006 19.6 0.0 0.0007 19.4 0.0 1.1 1 0 0 1 1 1 1 MafB19-like deaminase APOBEC2 PF18772.1 KXS19617.1 - 0.0022 18.1 0.0 0.0029 17.7 0.0 1.1 1 0 0 1 1 1 1 APOBEC2 SNAD4 PF18750.1 KXS19617.1 - 0.0029 17.7 0.0 0.0041 17.2 0.0 1.2 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 DUF769 PF05590.11 KXS19617.1 - 0.028 13.9 0.0 0.04 13.4 0.0 1.2 1 0 0 1 1 1 0 Xylella fastidiosa protein of unknown function (DUF769) NAD1 PF18778.1 KXS19617.1 - 0.074 13.1 0.1 0.097 12.8 0.1 1.1 1 0 0 1 1 1 0 Novel AID APOBEC clade 1 APOBEC_N PF08210.11 KXS19617.1 - 0.1 12.5 0.0 0.13 12.1 0.0 1.1 1 0 0 1 1 1 0 APOBEC-like N-terminal domain NAD2 PF18782.1 KXS19617.1 - 0.17 12.0 0.0 0.23 11.6 0.0 1.1 1 0 0 1 1 1 0 Novel AID APOBEC clade 2 zf-SNAP50_C PF12251.8 KXS19618.1 - 3.4e-26 92.2 0.0 4.6e-26 91.7 0.0 1.1 1 0 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal Exo_endo_phos PF03372.23 KXS19619.1 - 7.3e-10 38.8 0.6 2.2e-09 37.2 0.6 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-RING_11 PF17123.5 KXS19621.1 - 1.1e-05 25.1 0.5 2.7e-05 23.8 0.5 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 KXS19621.1 - 0.00033 20.9 0.2 0.00033 20.9 0.2 1.7 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 KXS19621.1 - 0.022 14.6 0.5 0.022 14.6 0.5 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXS19621.1 - 0.063 13.3 2.1 0.11 12.6 0.8 1.9 2 0 0 2 2 2 0 RING-type zinc-finger zf-C3HC4 PF00097.25 KXS19621.1 - 0.13 12.2 0.9 2.3 8.2 0.1 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) NTPase_1 PF03266.15 KXS19622.1 - 3.7e-06 27.0 0.1 0.076 12.9 0.0 2.5 2 0 0 2 2 2 2 NTPase T2SSE PF00437.20 KXS19622.1 - 1.6e-05 24.1 0.2 2.3e-05 23.6 0.2 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA PF00004.29 KXS19622.1 - 2.1e-05 24.9 0.0 4.1e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KXS19622.1 - 8.7e-05 22.3 0.0 0.00016 21.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KXS19622.1 - 9.5e-05 22.8 0.1 0.00043 20.7 0.0 1.9 1 1 1 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 KXS19622.1 - 0.0017 18.0 0.1 0.094 12.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain TniB PF05621.11 KXS19622.1 - 0.003 17.0 0.3 5.7 6.3 0.0 3.0 3 0 0 3 3 3 2 Bacterial TniB protein AAA_19 PF13245.6 KXS19622.1 - 0.0034 17.7 0.0 0.097 13.0 0.0 2.5 3 0 0 3 3 3 1 AAA domain AAA_11 PF13086.6 KXS19622.1 - 0.0035 17.2 0.1 0.55 10.0 0.0 2.2 1 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KXS19622.1 - 0.0035 17.6 0.1 0.018 15.3 0.1 2.0 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 KXS19622.1 - 0.0051 17.3 0.1 0.011 16.3 0.1 1.9 1 1 0 1 1 1 1 ABC transporter NACHT PF05729.12 KXS19622.1 - 0.0058 16.6 0.1 0.018 15.0 0.0 1.8 2 0 0 2 2 2 1 NACHT domain AAA_5 PF07728.14 KXS19622.1 - 0.006 16.6 0.0 0.013 15.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 KXS19622.1 - 0.0089 15.8 0.0 0.069 12.9 0.0 2.2 1 1 0 1 1 1 1 AAA domain TrwB_AAD_bind PF10412.9 KXS19622.1 - 0.016 14.2 0.1 0.036 13.0 0.0 1.6 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain ATPase PF06745.13 KXS19622.1 - 0.019 14.3 0.3 0.093 12.1 0.0 2.0 2 0 0 2 2 2 0 KaiC AAA_18 PF13238.6 KXS19622.1 - 0.021 15.4 0.0 0.04 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KXS19622.1 - 0.031 14.3 0.0 0.099 12.7 0.0 1.8 1 1 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 KXS19622.1 - 0.032 14.0 0.0 0.067 12.9 0.0 1.6 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_28 PF13521.6 KXS19622.1 - 0.066 13.5 0.1 2.4 8.4 0.0 2.6 2 1 1 3 3 3 0 AAA domain MMR_HSR1 PF01926.23 KXS19622.1 - 0.089 12.9 0.0 0.33 11.0 0.0 2.0 2 0 0 2 2 2 0 50S ribosome-binding GTPase NB-ARC PF00931.22 KXS19622.1 - 0.11 11.6 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.22 KXS19622.1 - 0.12 12.8 0.0 0.6 10.5 0.0 2.2 1 1 0 1 1 1 0 RNA helicase Nup96 PF12110.8 KXS19623.1 - 4.1e-53 180.4 0.0 1.8e-52 178.3 0.0 1.9 1 1 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.14 KXS19623.1 - 8e-41 139.6 0.0 1.2e-40 139.0 0.0 1.3 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.6 KXS19623.1 - 1.2e-23 83.8 216.5 1.4e-05 25.8 24.7 10.5 3 2 7 10 10 10 8 Nucleoporin FG repeat region EI24 PF07264.11 KXS19624.1 - 1.4 9.1 8.9 0.37 11.0 4.9 2.0 1 1 1 2 2 2 0 Etoposide-induced protein 2.4 (EI24) Colipase PF01114.18 KXS19625.1 - 0.021 14.5 0.7 0.044 13.5 0.7 1.4 1 0 0 1 1 1 0 Colipase, N-terminal domain TMEM208_SND2 PF05620.11 KXS19626.1 - 1.8e-35 122.2 0.5 1.9e-35 122.1 0.5 1.0 1 0 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 Ank_2 PF12796.7 KXS19627.1 - 3.7e-17 62.7 0.8 1.3e-10 41.7 0.2 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXS19627.1 - 4.7e-11 43.0 1.8 0.0037 17.8 0.3 2.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KXS19627.1 - 9.7e-11 41.6 3.2 4.6e-05 23.7 0.1 2.3 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 KXS19627.1 - 1e-10 40.9 0.4 4.5e-05 23.5 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 KXS19627.1 - 2.4e-10 40.5 2.2 2.1e-06 27.9 0.1 2.2 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Copine PF07002.16 KXS19628.1 - 1.6e-67 227.1 0.0 2.1e-67 226.8 0.0 1.1 1 0 0 1 1 1 1 Copine C2 PF00168.30 KXS19628.1 - 4.2e-21 75.2 0.0 2.4e-09 37.4 0.0 2.3 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.9 KXS19628.1 - 0.0026 17.9 0.0 0.005 17.0 0.0 1.4 1 0 0 1 1 1 1 vWA found in TerF C terminus DAHP_synth_2 PF01474.16 KXS19629.1 - 1.1e-184 614.1 0.0 1.2e-184 613.9 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family Pho88 PF10032.9 KXS19630.1 - 1.9e-46 157.6 0.0 2.2e-46 157.4 0.0 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) LT-IIB PF06453.11 KXS19630.1 - 0.031 14.2 0.0 0.051 13.5 0.0 1.3 1 0 0 1 1 1 0 Type II heat-labile enterotoxin , B subunit (LT-IIB) QCR10 PF09796.9 KXS19631.1 - 3.5e-15 55.8 0.2 4.5e-15 55.5 0.2 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) UCR_6-4kD PF08997.10 KXS19631.1 - 0.047 13.6 0.4 0.047 13.6 0.4 1.5 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase complex, 6.4kD protein Cupin_6 PF12852.7 KXS19632.1 - 0.21 11.3 1.8 17 5.0 0.2 2.8 1 1 1 2 2 2 0 Cupin DUF3974 PF13120.6 KXS19634.1 - 0.38 10.9 0.9 0.63 10.1 0.4 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3974) Apq12 PF12716.7 KXS19634.1 - 4.3 7.3 7.7 0.46 10.5 3.3 1.6 2 0 0 2 2 2 0 Nuclear pore assembly and biogenesis Cyclin_N PF00134.23 KXS19636.1 - 1.6e-30 105.5 0.1 2.3e-30 104.9 0.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KXS19636.1 - 2.1e-05 24.6 0.1 4.5e-05 23.5 0.1 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain Pyr_redox_2 PF07992.14 KXS19638.1 - 4.9e-51 173.7 0.2 5.7e-51 173.5 0.2 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXS19638.1 - 2.4e-18 66.4 0.0 1.6e-15 57.2 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXS19638.1 - 1.2e-14 54.6 0.0 6.5e-13 49.1 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KXS19638.1 - 5.7e-05 22.4 4.0 0.056 12.5 0.3 4.1 3 1 1 4 4 4 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 KXS19638.1 - 8.5e-05 22.1 0.1 0.0019 17.6 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 KXS19638.1 - 0.00022 20.6 0.0 0.00051 19.3 0.0 1.6 1 0 0 1 1 1 1 Thi4 family K_oxygenase PF13434.6 KXS19638.1 - 0.002 17.4 0.0 0.012 14.7 0.0 2.2 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 KXS19638.1 - 0.015 14.0 0.1 0.29 9.8 0.1 2.3 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_2 PF00890.24 KXS19638.1 - 0.021 13.9 2.3 0.16 11.0 0.2 2.8 2 1 1 3 3 3 0 FAD binding domain fragilysinNterm PF16376.5 KXS19638.1 - 0.033 13.9 0.0 0.069 12.9 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of fragilysin NAD_binding_7 PF13241.6 KXS19638.1 - 0.039 14.4 0.0 0.42 11.1 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding NAD_binding_8 PF13450.6 KXS19638.1 - 0.08 13.2 0.5 0.21 11.8 0.1 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Tmemb_14 PF03647.13 KXS19640.1 - 0.00015 22.4 7.1 0.00021 22.0 7.1 1.2 1 0 0 1 1 1 1 Transmembrane proteins 14C Ycf66_N PF07444.11 KXS19640.1 - 0.07 13.3 0.2 0.17 12.0 0.1 1.7 1 1 1 2 2 2 0 Ycf66 protein N-terminus Cellulase PF00150.18 KXS19641.1 - 2.7e-14 53.3 7.0 1.3e-12 47.8 0.5 2.1 2 0 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_53 PF07745.13 KXS19641.1 - 0.043 12.8 0.4 1.2 8.0 0.2 2.3 2 0 0 2 2 2 0 Glycosyl hydrolase family 53 ETRAMP PF09716.10 KXS19641.1 - 0.08 13.0 0.3 0.14 12.2 0.3 1.3 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Dec-1 PF04624.14 KXS19641.1 - 2.3 8.1 6.6 4.4 7.2 6.6 1.4 1 0 0 1 1 1 0 Dec-1 repeat GATase PF00117.28 KXS19643.1 - 3.4e-11 43.3 0.0 4.3e-11 42.9 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KXS19643.1 - 0.15 11.8 0.0 0.35 10.6 0.0 1.5 2 0 0 2 2 2 0 Peptidase C26 Abhydrolase_3 PF07859.13 KXS19644.1 - 9.6e-40 136.7 0.0 1.4e-39 136.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KXS19644.1 - 2.6e-14 52.9 0.0 3.8e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 KXS19644.1 - 3e-05 23.6 0.0 5.3e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 KXS19644.1 - 0.00013 21.8 0.0 0.0019 18.0 0.0 2.1 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 KXS19644.1 - 0.00014 22.6 3.8 0.00014 22.6 3.8 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family COesterase PF00135.28 KXS19644.1 - 0.00073 18.5 0.3 0.0097 14.8 0.0 2.0 2 0 0 2 2 2 1 Carboxylesterase family Hydrolase_4 PF12146.8 KXS19644.1 - 0.018 14.3 0.0 0.048 12.9 0.0 1.6 1 1 0 1 1 1 0 Serine aminopeptidase, S33 LIM PF00412.22 KXS19647.1 - 3.4e-24 84.8 19.8 2.6e-12 46.8 6.3 2.1 2 0 0 2 2 2 2 LIM domain zf_UBZ PF18439.1 KXS19647.1 - 0.00026 20.5 14.8 0.73 9.5 0.5 4.4 4 0 0 4 4 4 4 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 KXS19647.1 - 0.018 15.1 21.5 0.75 10.0 1.2 4.2 4 0 0 4 4 4 0 Zinc ribbon domain NinD PF17466.2 KXS19647.1 - 0.17 12.0 4.4 1.3 9.1 0.7 2.6 2 0 0 2 2 2 0 Family of unknown function Lar_restr_allev PF14354.6 KXS19647.1 - 0.25 11.8 22.4 4 7.9 8.6 3.3 2 2 0 2 2 2 0 Restriction alleviation protein Lar CAP_N PF01213.19 KXS19647.1 - 0.78 9.2 2.6 0.98 8.8 2.6 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal zf-CCHC_5 PF14787.6 KXS19647.1 - 2.8 7.7 0.0 2.8 7.7 0.0 4.2 4 0 0 4 4 4 0 GAG-polyprotein viral zinc-finger zf-C3HC4_5 PF17121.5 KXS19647.1 - 4.1 7.4 12.8 0.28 11.1 0.6 3.0 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-DNA_Pol PF08996.10 KXS19647.1 - 4.4 7.0 12.7 4.1 7.1 1.5 2.2 2 0 0 2 2 2 0 DNA Polymerase alpha zinc finger YacG PF03884.14 KXS19647.1 - 5.6 6.8 11.6 6.9 6.5 0.3 3.6 4 0 0 4 4 4 0 DNA gyrase inhibitor YacG MFS_1 PF07690.16 KXS19648.1 - 8.3e-24 84.2 41.0 1.3e-23 83.6 37.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ABC_tran_Xtn PF12848.7 KXS19649.1 - 9.3e-05 22.4 3.3 9.3e-05 22.4 3.3 2.3 2 1 0 2 2 2 1 ABC transporter PKK PF12474.8 KXS19650.1 - 0.033 14.3 1.3 0.054 13.6 1.3 1.2 1 0 0 1 1 1 0 Polo kinase kinase DNA_pol_phi PF04931.13 KXS19652.1 - 0.14 10.3 3.7 0.1 10.7 3.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi GCIP PF13324.6 KXS19652.1 - 0.54 9.8 3.0 0.67 9.5 3.0 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Cwf_Cwc_15 PF04889.12 KXS19652.1 - 4 7.1 10.0 7.1 6.3 10.0 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 KXS19652.1 - 6.4 4.9 7.4 7.7 4.6 7.4 1.1 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.12 KXS19652.1 - 8.5 5.6 10.8 13 5.0 10.8 1.3 1 0 0 1 1 1 0 NOA36 protein PP_M1 PF03012.14 KXS19652.1 - 8.6 5.8 6.4 3.7 7.0 4.0 1.5 2 0 0 2 2 2 0 Phosphoprotein zf-HC5HC2H PF13771.6 KXS19654.1 - 0.078 13.2 0.1 0.15 12.3 0.1 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain Rol_Rep_N PF18106.1 KXS19654.1 - 0.14 12.5 0.0 0.46 10.8 0.0 1.8 2 0 0 2 2 2 0 Rolling Circle replication initiation protein N-terminal domain Band_7 PF01145.25 KXS19657.1 - 8.6e-24 84.5 4.5 1.3e-23 83.9 4.5 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Med2 PF11214.8 KXS19657.1 - 0.051 13.7 0.6 0.1 12.7 0.6 1.5 1 0 0 1 1 1 0 Mediator complex subunit 2 Methyltransf_5 PF01795.19 KXS19657.1 - 0.079 12.5 3.0 0.11 11.9 3.0 1.3 1 1 0 1 1 1 0 MraW methylase family DEAD PF00270.29 KXS19658.1 - 2.9e-46 157.4 0.0 5.5e-46 156.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXS19658.1 - 3e-24 85.5 0.0 9.4e-24 83.9 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KXS19658.1 - 1.4e-18 66.9 0.7 4.9e-18 65.1 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KXS19658.1 - 2.4e-06 27.7 0.9 5.6e-06 26.5 0.0 2.1 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit tRNA-synt_1c PF00749.21 KXS19659.1 - 1.6e-107 359.1 0.0 2.3e-107 358.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA_synt_1c_R1 PF04558.15 KXS19659.1 - 3e-45 154.1 0.0 5.1e-45 153.4 0.0 1.4 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA-synt_1c_C PF03950.18 KXS19659.1 - 2.6e-40 138.1 0.0 4.5e-40 137.4 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R2 PF04557.15 KXS19659.1 - 4.6e-12 46.7 4.3 9.6e-12 45.7 4.3 1.5 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 ACT_5 PF13710.6 KXS19659.1 - 0.068 13.0 0.1 0.21 11.4 0.1 1.8 1 0 0 1 1 1 0 ACT domain DUF3892 PF13031.6 KXS19659.1 - 0.15 12.7 0.2 0.75 10.5 0.2 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3892) LRR_6 PF13516.6 KXS19660.1 - 5.7e-40 132.0 44.7 1.4e-05 24.8 0.5 12.6 12 0 0 12 12 12 9 Leucine Rich repeat Sel1 PF08238.12 KXS19660.1 - 2.9e-38 129.4 22.9 5.8e-08 33.2 0.2 9.6 9 0 0 9 9 9 6 Sel1 repeat Pkinase_Tyr PF07714.17 KXS19660.1 - 5e-27 94.8 0.0 9.7e-27 93.9 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXS19660.1 - 2.2e-26 92.8 0.0 8.9e-26 90.8 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain LRR_4 PF12799.7 KXS19660.1 - 6.4e-07 29.6 16.0 0.69 10.4 0.6 6.4 5 2 1 6 6 6 4 Leucine Rich repeats (2 copies) TPR_8 PF13181.6 KXS19660.1 - 9.3e-06 25.5 3.4 0.16 12.2 0.0 4.9 5 0 0 5 5 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 KXS19660.1 - 0.00015 21.4 5.9 0.055 13.3 0.1 4.5 3 0 0 3 3 3 1 Tetratricopeptide repeat LRR_1 PF00560.33 KXS19660.1 - 0.00016 21.8 2.3 27 5.8 0.1 6.7 7 0 0 7 7 6 0 Leucine Rich Repeat TPR_2 PF07719.17 KXS19660.1 - 0.00081 19.3 16.4 0.036 14.2 0.1 5.8 6 0 0 6 6 6 2 Tetratricopeptide repeat APH PF01636.23 KXS19660.1 - 0.0029 17.6 0.3 0.0085 16.0 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family TPR_16 PF13432.6 KXS19660.1 - 0.0074 16.9 17.8 0.052 14.2 3.0 4.6 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 KXS19660.1 - 0.012 15.9 8.1 0.3 11.4 0.5 4.6 3 1 1 4 4 4 0 Tetratricopeptide repeat SpoU_sub_bind PF08032.12 KXS19660.1 - 0.013 15.8 0.2 47 4.4 0.0 4.2 4 0 0 4 4 3 0 RNA 2'-O ribose methyltransferase substrate binding Kinase-like PF14531.6 KXS19660.1 - 0.018 14.4 0.0 0.027 13.8 0.0 1.2 1 0 0 1 1 1 0 Kinase-like TPR_10 PF13374.6 KXS19660.1 - 0.023 14.5 1.6 2.9 7.9 0.0 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat LRR_8 PF13855.6 KXS19660.1 - 0.065 13.0 18.6 1.5 8.7 1.4 6.2 4 3 0 4 4 4 0 Leucine rich repeat TPR_19 PF14559.6 KXS19660.1 - 0.2 12.2 8.3 1.4 9.5 4.2 3.7 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 KXS19660.1 - 0.95 9.6 9.9 3.5 7.9 0.0 4.9 5 0 0 5 5 4 0 Tetratricopeptide repeat Arm-DNA-bind_1 PF09003.10 KXS19660.1 - 8.7 6.6 7.8 1.3e+02 2.8 0.1 4.3 3 1 1 4 4 4 0 Bacteriophage lambda integrase, Arm DNA-binding domain Vps39_2 PF10367.9 KXS19661.1 - 1.9e-19 70.1 0.0 4.6e-19 68.9 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.9 KXS19661.1 - 2.8e-14 53.3 0.0 4.3e-12 46.3 0.0 3.4 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 CNH PF00780.22 KXS19661.1 - 3.6e-10 39.9 0.0 1e-09 38.4 0.0 1.8 1 1 0 1 1 1 1 CNH domain Clathrin PF00637.20 KXS19661.1 - 6.3e-07 29.4 0.3 0.0094 15.8 0.0 4.6 3 2 1 4 4 4 2 Region in Clathrin and VPS TPR_7 PF13176.6 KXS19661.1 - 0.022 14.8 2.0 0.72 10.0 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 KXS19661.1 - 0.026 14.8 0.7 7 7.0 0.0 3.9 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 KXS19661.1 - 0.39 11.0 2.1 14 6.1 0.0 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat SNF2_N PF00176.23 KXS19662.1 - 3.9e-59 200.1 0.4 7.7e-59 199.2 0.4 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KXS19662.1 - 1e-18 67.7 0.6 7.6e-18 64.9 0.0 2.7 4 0 0 4 4 4 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXS19662.1 - 9.4e-08 32.2 0.0 1.8e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KXS19662.1 - 1.1e-06 28.5 0.0 2.2e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 KXS19662.1 - 1.7e-05 24.1 0.0 0.00026 20.3 0.0 2.6 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 SWI2_SNF2 PF18766.1 KXS19662.1 - 0.0038 16.9 0.0 0.0099 15.6 0.0 1.7 1 0 0 1 1 1 1 SWI2/SNF2 ATPase PHD PF00628.29 KXS19662.1 - 0.0054 16.6 4.5 0.0054 16.6 4.5 2.7 3 0 0 3 3 3 2 PHD-finger HECT PF00632.25 KXS19663.1 - 1.8e-91 306.8 0.0 2.3e-91 306.5 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Pyr_redox_2 PF07992.14 KXS19664.1 - 5e-68 229.5 6.2 8.4e-68 228.7 6.2 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KXS19664.1 - 3.9e-39 133.3 1.1 3.9e-39 133.3 1.1 2.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KXS19664.1 - 1.9e-17 63.6 7.4 2.6e-14 53.5 1.3 3.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KXS19664.1 - 1.8e-11 44.1 0.9 2.7e-11 43.5 0.9 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KXS19664.1 - 3e-08 32.8 7.7 0.00045 19.0 1.2 3.4 3 1 1 4 4 4 2 HI0933-like protein FAD_binding_2 PF00890.24 KXS19664.1 - 4.2e-08 32.7 3.6 1.7e-07 30.7 2.7 2.2 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.22 KXS19664.1 - 6.2e-08 32.1 8.4 7e-07 28.7 8.4 2.4 1 1 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 KXS19664.1 - 5.3e-07 29.8 2.0 5.4e-05 23.3 0.3 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KXS19664.1 - 5.3e-05 22.5 0.0 0.0046 16.1 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 KXS19664.1 - 0.00012 21.4 0.3 0.00012 21.4 0.3 2.4 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 KXS19664.1 - 0.0061 15.9 1.3 0.0061 15.9 1.3 3.2 2 1 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.21 KXS19664.1 - 0.015 14.6 12.6 0.18 11.0 1.3 3.2 3 1 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 KXS19664.1 - 0.03 13.6 13.1 0.13 11.5 1.4 4.0 3 1 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Antig_Caf1 PF09255.10 KXS19664.1 - 0.055 13.6 0.1 0.23 11.5 0.0 2.1 2 0 0 2 2 2 0 Caf1 Capsule antigen Lycopene_cycl PF05834.12 KXS19664.1 - 0.21 10.6 0.6 0.62 9.1 0.6 1.9 1 1 0 1 1 1 0 Lycopene cyclase protein PPR_2 PF13041.6 KXS19665.1 - 1.1e-05 25.5 0.0 0.0028 17.8 0.0 3.3 3 1 0 3 3 3 1 PPR repeat family PPR PF01535.20 KXS19665.1 - 0.016 15.4 3.8 0.45 10.9 0.1 4.1 5 1 1 6 6 6 0 PPR repeat PPR_long PF17177.4 KXS19665.1 - 0.11 11.8 0.0 5.2 6.4 0.0 2.5 2 0 0 2 2 2 0 Pentacotripeptide-repeat region of PRORP PPR_3 PF13812.6 KXS19665.1 - 0.23 11.6 0.0 13 5.9 0.0 3.1 3 0 0 3 3 3 0 Pentatricopeptide repeat domain FMO-like PF00743.19 KXS19666.1 - 1.8e-11 43.2 0.0 4.5e-11 41.9 0.0 1.6 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KXS19666.1 - 2.8e-10 40.0 0.0 2.7e-07 30.1 0.0 3.1 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXS19666.1 - 2.9e-08 33.3 0.0 4e-05 23.0 0.0 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXS19666.1 - 1.8e-07 31.3 0.0 8.9e-06 25.9 0.0 3.2 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KXS19666.1 - 2.6e-06 26.9 0.0 0.0006 19.1 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 KXS19666.1 - 0.0021 18.6 0.1 4.4 7.9 0.1 3.4 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 KXS19666.1 - 0.007 15.8 0.0 0.015 14.7 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DAO PF01266.24 KXS19666.1 - 0.016 14.8 0.3 0.95 9.0 0.1 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KXS19666.1 - 0.026 14.5 0.1 1.7 8.6 0.0 3.0 3 0 0 3 3 3 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 KXS19666.1 - 0.088 11.9 0.1 1.1 8.3 0.1 2.3 2 0 0 2 2 2 0 FAD binding domain TPT PF03151.16 KXS19667.1 - 2.8e-10 40.0 11.5 3.1e-10 39.9 3.1 2.1 2 0 0 2 2 2 2 Triose-phosphate Transporter family UAA PF08449.11 KXS19667.1 - 0.0043 16.3 0.5 0.0043 16.3 0.5 2.1 2 0 0 2 2 2 1 UAA transporter family DUF202 PF02656.15 KXS19667.1 - 4.2 7.9 18.5 7.1 7.2 0.8 4.1 3 2 0 3 3 3 0 Domain of unknown function (DUF202) Ribosomal_L18 PF17135.4 KXS19668.1 - 2.8e-92 307.2 0.7 3.2e-92 307.1 0.7 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 KXS19668.1 - 0.00024 21.8 0.0 0.00077 20.1 0.0 1.9 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A DUF3348 PF11828.8 KXS19671.1 - 0.097 12.3 0.1 0.23 11.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3348) TFIIF_alpha PF05793.12 KXS19673.1 - 0.028 13.0 4.2 0.032 12.8 4.2 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PRIMA1 PF16101.5 KXS19673.1 - 0.13 12.3 5.5 0.19 11.8 5.5 1.2 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 CAP_N PF01213.19 KXS19673.1 - 0.5 9.8 5.8 0.69 9.3 5.8 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal zf-rbx1 PF12678.7 KXS19674.1 - 4e-05 23.8 2.6 0.00057 20.1 0.3 2.6 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KXS19674.1 - 0.03 14.6 12.9 0.037 14.3 0.8 3.0 3 1 1 4 4 4 0 Ring finger domain zf-C3HC4_3 PF13920.6 KXS19674.1 - 0.54 10.2 5.9 14 5.6 0.1 3.4 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 KXS19674.1 - 0.8 9.6 8.1 0.41 10.6 1.9 2.5 2 0 0 2 2 2 0 PHD-finger Prok-RING_1 PF14446.6 KXS19674.1 - 0.86 9.6 7.2 0.59 10.1 0.8 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-C3HC4 PF00097.25 KXS19674.1 - 1 9.3 8.1 1.4 8.8 0.0 3.1 4 1 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXS19674.1 - 2.6 7.9 9.6 3.8 7.4 0.1 3.1 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) OrfB_Zn_ribbon PF07282.11 KXS19674.1 - 3.9 7.5 6.0 4.4 7.3 0.1 2.5 2 1 0 2 2 2 0 Putative transposase DNA-binding domain RNA_POL_M_15KD PF02150.16 KXS19674.1 - 4.2 7.3 7.3 1.8 8.5 0.3 2.8 3 0 0 3 3 3 0 RNA polymerases M/15 Kd subunit CAP_N PF01213.19 KXS19675.1 - 3.7 6.9 5.5 5.5 6.4 5.5 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal p450 PF00067.22 KXS19677.1 - 6e-06 25.3 0.0 1.4e-05 24.0 0.0 1.5 2 0 0 2 2 2 1 Cytochrome P450 Rad51 PF08423.11 KXS19678.1 - 4.9e-08 32.6 0.0 0.0049 16.2 0.0 2.2 2 0 0 2 2 2 2 Rad51 IIGP PF05049.13 KXS19679.1 - 6.6e-16 58.3 0.0 8.6e-16 58.0 0.0 1.1 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) MMR_HSR1 PF01926.23 KXS19679.1 - 5.9e-06 26.3 0.0 1.1e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 KXS19679.1 - 0.00099 18.7 0.0 0.0016 18.0 0.0 1.3 1 0 0 1 1 1 1 Ras family RsgA_GTPase PF03193.16 KXS19679.1 - 0.0025 17.8 0.6 0.0096 15.8 0.0 2.2 2 1 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 KXS19679.1 - 0.01 16.1 0.0 0.022 15.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Roc PF08477.13 KXS19679.1 - 0.018 15.2 0.0 0.043 14.0 0.0 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Viral_helicase1 PF01443.18 KXS19679.1 - 0.12 12.1 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_7 PF12775.7 KXS19679.1 - 0.13 11.8 0.0 0.68 9.4 0.0 2.0 3 0 0 3 3 3 0 P-loop containing dynein motor region ATP_bind_1 PF03029.17 KXS19679.1 - 0.13 12.0 2.5 3.8 7.2 0.2 2.6 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein DUF815 PF05673.13 KXS19679.1 - 0.15 11.2 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_16 PF13191.6 KXS19679.1 - 0.15 12.4 0.0 0.31 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 KXS19679.1 - 0.16 12.1 0.0 1.8 8.7 0.0 2.4 3 0 0 3 3 3 0 AAA domain IIGP PF05049.13 KXS19680.1 - 2.4e-21 76.2 0.2 3.3e-21 75.8 0.2 1.1 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) MMR_HSR1 PF01926.23 KXS19680.1 - 2.8e-09 37.1 0.0 7.6e-09 35.7 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KXS19680.1 - 2e-08 33.9 0.1 3.5e-08 33.1 0.1 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KXS19680.1 - 1.4e-05 25.0 0.2 8.7e-05 22.5 0.0 2.2 2 1 0 2 2 2 1 RsgA GTPase ABC_tran PF00005.27 KXS19680.1 - 0.00029 21.4 0.0 0.0007 20.1 0.0 1.6 1 0 0 1 1 1 1 ABC transporter GTP_EFTU PF00009.27 KXS19680.1 - 0.00032 20.3 0.6 0.11 12.0 0.1 2.2 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain T2SSE PF00437.20 KXS19680.1 - 0.0013 17.9 0.9 0.0022 17.1 0.1 1.8 2 1 0 2 2 2 1 Type II/IV secretion system protein Roc PF08477.13 KXS19680.1 - 0.0037 17.5 0.0 0.0063 16.7 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 KXS19680.1 - 0.0041 16.8 0.1 0.0078 15.9 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 KXS19680.1 - 0.0067 16.8 0.7 0.017 15.5 0.2 2.0 1 1 1 2 2 2 1 AAA ATPase domain AIG1 PF04548.16 KXS19680.1 - 0.011 15.0 0.0 0.019 14.3 0.0 1.4 1 0 0 1 1 1 0 AIG1 family AAA_30 PF13604.6 KXS19680.1 - 0.019 14.7 1.4 0.038 13.7 0.2 1.9 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 KXS19680.1 - 0.02 15.0 0.2 0.049 13.7 0.1 1.7 2 0 0 2 2 2 0 Dynamin family NACHT PF05729.12 KXS19680.1 - 0.031 14.2 0.0 0.072 13.0 0.0 1.6 1 0 0 1 1 1 0 NACHT domain Viral_helicase1 PF01443.18 KXS19680.1 - 0.036 13.8 0.0 0.069 12.9 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_28 PF13521.6 KXS19680.1 - 0.071 13.4 0.2 0.16 12.2 0.2 1.6 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 KXS19680.1 - 0.081 12.5 0.2 0.2 11.2 0.2 1.7 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.22 KXS19680.1 - 0.092 13.1 0.0 0.23 11.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_21 PF13304.6 KXS19680.1 - 0.096 12.5 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KXS19680.1 - 0.099 12.1 1.3 0.33 10.4 0.2 2.0 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain Septin PF00735.18 KXS19680.1 - 0.1 11.9 0.0 0.2 10.9 0.0 1.5 1 0 0 1 1 1 0 Septin AAA_22 PF13401.6 KXS19680.1 - 0.11 12.8 0.0 0.3 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KXS19680.1 - 0.11 13.0 0.2 0.19 12.3 0.2 1.6 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 KXS19680.1 - 0.12 11.7 0.1 0.23 10.8 0.1 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Guanylate_kin PF00625.21 KXS19680.1 - 0.13 12.0 0.1 0.57 9.8 0.0 2.0 2 0 0 2 2 2 0 Guanylate kinase Mg_chelatase PF01078.21 KXS19680.1 - 0.14 11.5 0.0 0.27 10.6 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NB-ARC PF00931.22 KXS19680.1 - 0.15 11.2 0.0 0.26 10.4 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_23 PF13476.6 KXS19680.1 - 0.17 12.4 0.0 0.36 11.3 0.0 1.5 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 KXS19680.1 - 0.38 10.6 2.1 0.34 10.8 0.2 1.9 2 1 1 3 3 2 0 NTPase TPR_7 PF13176.6 KXS19681.1 - 0.052 13.6 0.1 9.5 6.5 0.0 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 KXS19681.1 - 0.15 12.3 0.1 15 6.0 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Octapeptide PF03373.14 KXS19683.1 - 0.19 12.2 1.4 0.91 10.1 1.4 2.2 1 0 0 1 1 1 0 Octapeptide repeat L_HMGIC_fpl PF10242.9 KXS19684.1 - 0.021 15.0 0.1 0.023 14.9 0.1 1.2 1 0 0 1 1 1 0 Lipoma HMGIC fusion partner-like protein Fz PF01392.22 KXS19685.1 - 8.1e-09 36.1 4.5 1.2e-08 35.5 4.5 1.2 1 0 0 1 1 1 1 Fz domain Myco_arth_vir_N PF09610.10 KXS19685.1 - 0.66 10.1 2.0 1.7 8.8 2.0 1.7 1 0 0 1 1 1 0 Mycoplasma virulence signal region (Myco_arth_vir_N) LRR_4 PF12799.7 KXS19686.1 - 8.2e-06 26.1 3.7 0.16 12.4 0.5 3.4 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXS19686.1 - 9e-05 22.2 1.0 0.0028 17.4 0.1 2.7 2 0 0 2 2 2 1 Leucine rich repeat LRR_1 PF00560.33 KXS19686.1 - 0.0021 18.3 2.5 0.71 10.7 0.1 4.2 4 0 0 4 4 4 1 Leucine Rich Repeat LRR_6 PF13516.6 KXS19686.1 - 0.21 11.7 1.3 13 6.1 0.1 3.3 3 0 0 3 3 3 0 Leucine Rich repeat TPR_2 PF07719.17 KXS19687.1 - 0.0038 17.2 2.5 1.1 9.5 0.1 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 KXS19687.1 - 0.054 14.0 5.5 4.4 7.9 0.9 3.0 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 KXS19687.1 - 0.084 13.7 7.0 12 7.0 0.6 3.3 2 1 2 4 4 4 0 Tetratricopeptide repeat DUF3819 PF12842.7 KXS19687.1 - 0.12 12.3 0.0 0.2 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3819) Sel1 PF08238.12 KXS19687.1 - 0.32 11.8 3.4 18 6.2 0.0 3.8 4 1 0 4 4 4 0 Sel1 repeat Pkinase_Tyr PF07714.17 KXS19688.1 - 1.3e-49 168.8 0.0 1.5e-49 168.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXS19688.1 - 1.1e-36 126.6 0.0 1.4e-36 126.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 KXS19688.1 - 0.0001 21.8 0.0 0.00013 21.4 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KXS19688.1 - 0.059 12.7 0.0 0.092 12.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KXS19688.1 - 0.11 12.1 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Nucleoside_tran PF01733.18 KXS19689.1 - 2e-27 96.4 18.1 3.9e-25 88.9 0.5 2.8 3 0 0 3 3 3 2 Nucleoside transporter YesK PF14150.6 KXS19689.1 - 3.7 7.8 7.3 0.53 10.5 1.1 2.8 3 0 0 3 3 3 0 YesK-like protein Glyco_hydro_114 PF03537.13 KXS19690.1 - 4.9e-62 209.3 0.1 8.1e-62 208.5 0.1 1.3 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 Chitin_bind_1 PF00187.19 KXS19690.1 - 2.9e-09 37.2 20.6 2.9e-09 37.2 20.6 2.8 3 0 0 3 3 3 1 Chitin recognition protein Ribosomal_L27A PF00828.19 KXS19691.1 - 1.4e-20 74.3 1.5 1.8e-20 73.9 1.5 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A RTC4 PF14474.6 KXS19691.1 - 0.12 12.5 0.2 0.26 11.5 0.2 1.5 1 1 0 1 1 1 0 RTC4-like domain Myb_DNA-binding PF00249.31 KXS19692.1 - 0.00011 22.3 0.1 0.066 13.4 0.0 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain DUF4611 PF15387.6 KXS19692.1 - 0.23 11.7 5.5 0.44 10.8 0.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Cellulase PF00150.18 KXS19693.1 - 2.9e-12 46.6 0.3 2.9e-10 40.0 0.0 2.3 2 0 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) ApbA PF02558.16 KXS19694.1 - 1.3e-26 93.0 0.0 2.1e-26 92.4 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 KXS19694.1 - 5.7e-26 91.2 0.1 2.7e-25 89.0 0.0 1.9 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA C terminal DsrH PF04077.12 KXS19694.1 - 0.053 13.7 0.4 1.2 9.3 0.0 2.8 3 0 0 3 3 3 0 DsrH like protein Cid2 PF09774.9 KXS19696.1 - 1.8e-16 60.9 4.5 8.4e-11 42.5 1.3 2.0 1 1 1 2 2 2 2 Caffeine-induced death protein 2 GLTP PF08718.11 KXS19696.1 - 0.02 15.2 0.2 0.024 14.9 0.2 1.2 1 0 0 1 1 1 0 Glycolipid transfer protein (GLTP) BPL_N PF09825.9 KXS19696.1 - 0.13 11.3 0.4 0.15 11.1 0.4 1.1 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal Peptidase_C12 PF01088.21 KXS19697.1 - 2e-61 207.4 0.0 2.8e-61 206.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 KXS19697.1 - 2.7e-14 52.8 2.0 4.8e-14 52.0 2.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases DUF4539 PF15072.6 KXS19698.1 - 1.3e-10 41.2 0.0 1.8e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4539) AMP-binding PF00501.28 KXS19700.1 - 6.1e-64 216.2 0.0 1.8e-63 214.6 0.0 1.6 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXS19700.1 - 3.9e-18 66.2 0.5 7.6e-18 65.3 0.5 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Ytp1 PF10355.9 KXS19701.1 - 1.7e-26 93.1 1.4 5.5e-26 91.4 1.4 1.7 1 1 0 1 1 1 1 Protein of unknown function (Ytp1) SLAC1 PF03595.17 KXS19701.1 - 0.0084 15.4 1.1 0.0084 15.4 1.1 2.1 2 0 0 2 2 2 1 Voltage-dependent anion channel PAD PF03068.15 KXS19703.1 - 5.9e-52 177.0 0.0 5e-23 81.7 0.0 3.0 3 0 0 3 3 3 3 Protein-arginine deiminase (PAD) FluMu_N PF17891.1 KXS19703.1 - 0.14 11.9 0.0 0.85 9.4 0.0 2.2 2 0 0 2 2 2 0 Mu-like prophage FluMu N-terminal domain zf-C2HC_2 PF13913.6 KXS19704.1 - 3.3e-19 68.3 7.8 3.3e-11 42.8 2.1 2.3 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-Di19 PF05605.12 KXS19704.1 - 9.1e-05 22.7 3.0 0.19 12.0 0.2 2.4 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding TRAF6_Z2 PF18048.1 KXS19704.1 - 0.015 15.4 4.1 1 9.5 0.2 2.9 3 0 0 3 3 3 0 TNF receptor-associated factor 6 zinc finger 2 zf-C2H2_jaz PF12171.8 KXS19704.1 - 0.065 13.5 0.2 4 7.8 0.0 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 KXS19704.1 - 0.1 13.5 10.3 0.86 10.6 0.5 3.4 4 0 0 4 4 3 0 C2H2-type zinc finger Rad50_zn_hook PF04423.14 KXS19704.1 - 0.13 12.1 2.5 1.1 9.2 0.5 2.7 2 0 0 2 2 2 0 Rad50 zinc hook motif Lar_restr_allev PF14354.6 KXS19704.1 - 0.14 12.5 2.3 16 5.9 0.0 2.9 2 0 0 2 2 2 0 Restriction alleviation protein Lar zf-FPG_IleRS PF06827.14 KXS19704.1 - 0.19 11.6 4.4 3.4 7.6 0.3 2.5 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS zinc_ribbon_9 PF14369.6 KXS19704.1 - 0.2 11.9 4.3 5.7 7.3 0.3 2.6 2 0 0 2 2 2 0 zinc-ribbon zf-C2H2 PF00096.26 KXS19704.1 - 0.25 11.9 5.2 3.3 8.3 0.1 2.9 3 0 0 3 3 3 0 Zinc finger, C2H2 type Tmemb_55A PF09788.9 KXS19704.1 - 0.34 9.9 2.2 12 4.9 0.2 2.8 2 0 0 2 2 2 0 Transmembrane protein 55A zf-RING_7 PF02591.15 KXS19704.1 - 0.36 11.1 2.1 6.6 7.0 0.3 2.6 2 0 0 2 2 2 0 C4-type zinc ribbon domain ADK_lid PF05191.14 KXS19704.1 - 0.8 9.7 5.2 11 6.1 1.5 2.8 2 0 0 2 2 2 0 Adenylate kinase, active site lid RTA1 PF04479.13 KXS19705.1 - 1.5e-51 174.9 13.9 1.9e-51 174.6 13.9 1.1 1 0 0 1 1 1 1 RTA1 like protein LapA_dom PF06305.11 KXS19705.1 - 0.0086 15.9 0.9 0.0086 15.9 0.9 3.5 4 1 1 5 5 5 1 Lipopolysaccharide assembly protein A domain DUF4173 PF13777.6 KXS19705.1 - 1.9 7.9 18.6 1.6 8.1 3.3 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4173) Polysacc_deac_1 PF01522.21 KXS19707.1 - 1.4e-19 70.3 0.0 2.7e-19 69.3 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase nec1 PF10379.9 KXS19707.1 - 0.39 10.2 3.9 1.5 8.3 0.0 2.7 3 0 0 3 3 3 0 Virulence protein nec1 Mito_carr PF00153.27 KXS19708.1 - 1.2e-65 217.4 1.8 3e-22 78.4 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Beta-lactamase PF00144.24 KXS19709.1 - 2.1e-22 79.8 6.4 4.4e-22 78.8 6.4 1.5 1 1 0 1 1 1 1 Beta-lactamase CRAL_TRIO PF00650.20 KXS19710.1 - 6.3e-35 120.2 0.0 1.2e-34 119.3 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KXS19710.1 - 5.4e-09 36.1 0.2 1.9e-08 34.3 0.0 2.1 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KXS19710.1 - 9.1e-05 22.6 0.0 0.0002 21.5 0.0 1.6 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Vps53_N PF04100.12 KXS19711.1 - 4.5e-82 276.0 0.0 7e-82 275.4 0.0 1.2 1 0 0 1 1 1 1 Vps53-like, N-terminal VPS53_C PF16854.5 KXS19711.1 - 1.2e-06 28.6 0.0 2e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 53 C-terminus Sec6 PF06046.13 KXS19711.1 - 3.5e-06 25.7 0.0 1.2e-05 23.9 0.0 1.8 2 0 0 2 2 2 1 Exocyst complex component Sec6 Vps54_N PF10475.9 KXS19711.1 - 0.003 16.9 0.0 0.0051 16.1 0.0 1.3 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex Sec15 PF04091.12 KXS19711.1 - 0.0031 17.0 0.0 0.0063 16.0 0.0 1.4 1 0 0 1 1 1 1 Exocyst complex subunit Sec15-like DUF2451 PF10474.9 KXS19711.1 - 0.0091 15.8 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) FlgM PF04316.13 KXS19711.1 - 0.019 15.3 0.2 0.21 12.0 0.0 2.6 2 0 0 2 2 2 0 Anti-sigma-28 factor, FlgM COG7 PF10191.9 KXS19711.1 - 0.027 12.8 0.2 1.8 6.7 0.0 2.2 2 0 0 2 2 2 0 Golgi complex component 7 (COG7) RINT1_TIP1 PF04437.13 KXS19711.1 - 0.22 10.4 0.0 0.37 9.6 0.0 1.5 1 1 0 1 1 1 0 RINT-1 / TIP-1 family SAP PF02037.27 KXS19712.1 - 3.2e-06 26.7 0.1 6.4e-06 25.8 0.1 1.5 1 0 0 1 1 1 1 SAP domain Glyco_hydro_26 PF02156.15 KXS19713.1 - 3.6e-08 33.2 3.2 1.6e-06 27.8 0.2 2.3 2 0 0 2 2 2 2 Glycosyl hydrolase family 26 EF-hand_5 PF13202.6 KXS19713.1 - 0.013 15.0 0.6 0.03 13.8 0.6 1.6 1 0 0 1 1 1 0 EF hand EF-hand_1 PF00036.32 KXS19713.1 - 0.057 13.0 1.5 0.14 11.8 1.5 1.6 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.6 KXS19713.1 - 0.095 12.7 0.8 0.25 11.4 0.8 1.7 1 0 0 1 1 1 0 EF-hand domain Methyltransf_24 PF13578.6 KXS19714.1 - 6.6e-06 27.1 0.2 1.2e-05 26.3 0.2 1.4 1 0 0 1 1 1 1 Methyltransferase domain CmcI PF04989.12 KXS19714.1 - 0.12 12.1 0.1 1.5 8.5 0.2 2.2 2 0 0 2 2 2 0 Cephalosporin hydroxylase DUF3759 PF12585.8 KXS19715.1 - 4.2e-10 39.5 2.3 6.2e-10 39.0 2.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) RapH_N PF18801.1 KXS19715.1 - 0.031 14.4 0.2 0.038 14.1 0.2 1.2 1 0 0 1 1 1 0 response regulator aspartate phosphatase H, N terminal Peptidase_C2 PF00648.21 KXS19717.1 - 6.8e-39 133.7 0.2 2.1e-38 132.0 0.0 1.9 2 0 0 2 2 2 1 Calpain family cysteine protease Calpain_III PF01067.22 KXS19717.1 - 3.9e-24 85.5 2.9 2.6e-07 31.0 0.0 6.2 4 2 0 4 4 4 3 Calpain large subunit, domain III MIT PF04212.18 KXS19717.1 - 2.5e-15 56.3 9.7 6.3e-11 42.2 0.9 2.4 2 0 0 2 2 2 2 MIT (microtubule interacting and transport) domain Cofilin_ADF PF00241.20 KXS19718.1 - 2.3e-25 88.7 0.4 2.6e-25 88.6 0.4 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein WD40 PF00400.32 KXS19719.1 - 1.1e-11 45.1 3.7 0.0002 22.1 0.0 5.7 5 1 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXS19719.1 - 0.00085 19.6 0.0 2.6 8.4 0.0 3.8 4 2 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain LuxS PF02664.15 KXS19719.1 - 0.022 14.4 0.3 0.059 13.1 0.0 1.8 3 0 0 3 3 3 0 S-Ribosylhomocysteinase (LuxS) Tim17 PF02466.19 KXS19720.1 - 3e-10 40.4 0.0 6.7e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family XPG_I PF00867.18 KXS19721.1 - 7.8e-24 83.8 0.0 1.4e-23 83.0 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 KXS19721.1 - 2.2e-22 79.4 0.0 5.4e-22 78.2 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.7 KXS19721.1 - 1.1e-05 25.1 0.0 1.5e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 XPG domain containing APP_E2 PF12925.7 KXS19721.1 - 0.027 14.2 0.2 0.043 13.5 0.2 1.2 1 0 0 1 1 1 0 E2 domain of amyloid precursor protein 5_3_exonuc PF01367.20 KXS19721.1 - 0.17 12.5 0.0 0.47 11.1 0.0 1.7 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold HTH_DeoR PF08220.12 KXS19722.1 - 0.082 12.7 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain CHD5 PF04420.14 KXS19722.1 - 1 9.2 3.3 1.3 8.9 2.6 1.5 1 1 0 1 1 1 0 CHD5-like protein DNA_pol_D_N PF18018.1 KXS19726.1 - 6.9e-43 145.9 0.0 1e-42 145.3 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain DNA_pol_E_B PF04042.16 KXS19726.1 - 2.9e-29 102.0 0.0 4.3e-29 101.4 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B BPL_LplA_LipB PF03099.19 KXS19728.1 - 1.4e-07 31.5 0.1 6.2e-07 29.4 0.1 2.0 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family APC1_C PF18122.1 KXS19729.1 - 5.7e-11 42.6 0.0 1.5e-10 41.3 0.0 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex sub unit 1 C-terminal domain PC_rep PF01851.22 KXS19729.1 - 0.058 13.8 5.3 0.69 10.5 0.1 4.5 4 0 0 4 4 4 0 Proteasome/cyclosome repeat DUF2773 PF10971.8 KXS19729.1 - 1.2 9.4 3.6 1.1e+02 3.1 0.0 4.2 4 1 1 5 5 5 0 Protein of unknown function (DUF2773) MOZ_SAS PF01853.18 KXS19730.1 - 3.6e-73 245.0 0.0 4.8e-73 244.6 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 KXS19730.1 - 9.6e-17 60.3 3.0 9.6e-17 60.3 3.0 2.9 2 1 0 2 2 2 1 MYST family zinc finger domain Acetyltransf_7 PF13508.7 KXS19730.1 - 0.00013 22.4 0.0 0.00028 21.2 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXS19730.1 - 0.018 15.3 0.0 0.035 14.3 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family zf-Sec23_Sec24 PF04810.15 KXS19730.1 - 0.029 14.4 0.4 0.27 11.3 0.2 2.3 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger IF2_N PF04760.15 KXS19730.1 - 0.035 13.9 0.0 0.22 11.3 0.0 2.1 2 0 0 2 2 2 0 Translation initiation factor IF-2, N-terminal region FR47 PF08445.10 KXS19730.1 - 0.077 13.0 0.0 0.32 11.0 0.0 1.9 2 0 0 2 2 2 0 FR47-like protein Tudor-knot PF11717.8 KXS19731.1 - 3.3e-09 36.5 0.1 7.5e-09 35.4 0.1 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Nodulin_late PF07127.11 KXS19732.1 - 0.0056 17.0 0.2 0.0085 16.4 0.2 1.3 1 0 0 1 1 1 1 Late nodulin protein F-box PF00646.33 KXS19733.1 - 0.031 14.1 0.0 0.092 12.7 0.0 1.8 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.7 KXS19733.1 - 0.091 12.7 0.1 0.22 11.5 0.1 1.7 1 0 0 1 1 1 0 F-box-like ANAPC4_WD40 PF12894.7 KXS19734.1 - 4.5e-11 42.9 0.0 0.00055 20.2 0.0 4.3 3 2 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KXS19734.1 - 3.8e-10 40.2 0.0 0.00021 22.0 0.0 4.7 5 0 0 5 5 5 2 WD domain, G-beta repeat PD40 PF07676.12 KXS19734.1 - 0.09 12.8 0.0 32 4.6 0.0 3.5 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KXS19734.1 - 0.19 10.6 0.0 9.2 5.1 0.0 2.9 3 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40 PF00400.32 KXS19735.1 - 2e-14 53.7 11.3 0.00074 20.3 0.2 5.7 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXS19735.1 - 9.3e-07 29.1 0.0 0.00085 19.6 0.0 3.6 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KXS19735.1 - 0.019 14.8 0.0 0.057 13.3 0.0 1.8 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KXS19735.1 - 0.03 13.3 0.0 0.37 9.7 0.0 2.3 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Guanylate_cyc PF00211.20 KXS19736.1 - 6.2e-35 120.5 0.2 1.1e-34 119.6 0.2 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain TPR_2 PF07719.17 KXS19736.1 - 0.068 13.3 0.0 0.22 11.7 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat 2-oxoacid_dh PF00198.23 KXS19737.1 - 6.8e-82 274.4 0.3 8.4e-82 274.1 0.3 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KXS19737.1 - 6.2e-19 67.6 0.2 1.3e-18 66.6 0.2 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme HlyD_3 PF13437.6 KXS19737.1 - 1.1e-05 26.1 0.1 0.0056 17.4 0.0 2.5 2 0 0 2 2 2 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 KXS19737.1 - 0.00019 21.2 0.0 0.029 14.2 0.0 2.5 1 1 1 2 2 2 1 Biotin-lipoyl like HlyD_D23 PF16576.5 KXS19737.1 - 0.0083 15.4 0.0 0.041 13.1 0.0 2.0 1 1 1 2 2 2 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion GCV_H PF01597.19 KXS19737.1 - 0.14 12.0 0.2 0.4 10.6 0.0 1.7 2 0 0 2 2 2 0 Glycine cleavage H-protein PRCC PF10253.9 KXS19737.1 - 1.6 9.5 4.8 2.5 8.9 4.8 1.3 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting DUF3391 PF11871.8 KXS19737.1 - 5 7.7 5.2 2.3e+02 2.3 0.0 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF3391) Methyltransf_15 PF09445.10 KXS19738.1 - 5.5e-35 120.4 0.0 8.1e-35 119.8 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_25 PF13649.6 KXS19738.1 - 2.2e-08 34.7 0.0 3.6e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 KXS19738.1 - 7.6e-07 29.0 0.0 9e-06 25.5 0.0 2.0 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_31 PF13847.6 KXS19738.1 - 1e-06 28.6 0.0 1.4e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 KXS19738.1 - 2.7e-05 23.9 0.0 4e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_11 PF08241.12 KXS19738.1 - 0.00022 21.8 0.0 0.00037 21.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXS19738.1 - 0.00051 19.4 0.0 0.00078 18.8 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.13 KXS19738.1 - 0.0017 17.8 0.0 0.0026 17.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Met_10 PF02475.16 KXS19738.1 - 0.0023 17.7 0.0 0.0033 17.2 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_18 PF12847.7 KXS19738.1 - 0.0036 17.2 0.0 0.0055 16.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXS19738.1 - 0.0037 16.8 0.0 0.0051 16.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_3 PF01596.17 KXS19738.1 - 0.019 14.2 0.0 0.029 13.6 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase tRNA_U5-meth_tr PF05958.11 KXS19738.1 - 0.079 11.9 0.0 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase TRM PF02005.16 KXS19738.1 - 0.097 11.8 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_5 PF01795.19 KXS19738.1 - 0.12 11.9 0.0 0.17 11.4 0.0 1.1 1 0 0 1 1 1 0 MraW methylase family Methyltransf_24 PF13578.6 KXS19738.1 - 0.15 13.1 0.0 0.23 12.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain AviRa PF11599.8 KXS19738.1 - 0.21 11.0 0.0 0.28 10.6 0.0 1.2 1 0 0 1 1 1 0 RRNA methyltransferase AviRa Cnd1 PF12717.7 KXS19739.1 - 2.2e-53 180.6 13.4 1e-51 175.2 1.0 5.5 7 1 0 7 7 7 2 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.7 KXS19739.1 - 7e-32 110.6 0.0 2.6e-31 108.7 0.0 2.1 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1, N-term HEAT_2 PF13646.6 KXS19739.1 - 8e-11 42.2 2.0 0.00011 22.5 0.0 5.3 5 1 1 6 6 5 3 HEAT repeats HEAT PF02985.22 KXS19739.1 - 7.5e-10 38.2 0.6 1.4 9.4 0.0 6.5 6 0 0 6 6 5 3 HEAT repeat Cnd3 PF12719.7 KXS19739.1 - 9.7e-06 25.0 8.2 0.018 14.3 1.3 3.9 4 0 0 4 4 4 2 Nuclear condensing complex subunits, C-term domain RTP1_C1 PF10363.9 KXS19739.1 - 7.2e-05 22.9 2.4 2.4 8.4 0.0 5.6 6 2 1 7 7 7 2 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 KXS19739.1 - 0.00011 22.6 0.1 5.6 7.6 0.0 5.5 6 0 0 6 6 5 1 HEAT-like repeat Adaptin_N PF01602.20 KXS19739.1 - 0.00093 17.9 1.8 0.00093 17.9 1.8 4.3 3 2 0 5 5 5 2 Adaptin N terminal region Arm_2 PF04826.13 KXS19739.1 - 0.0019 17.7 0.9 0.0045 16.5 0.9 1.7 1 0 0 1 1 1 1 Armadillo-like HTH_40 PF14493.6 KXS19739.1 - 0.047 14.1 0.7 16 6.1 0.1 3.0 2 0 0 2 2 2 0 Helix-turn-helix domain IFRD PF05004.13 KXS19739.1 - 0.058 12.5 14.8 0.63 9.1 0.1 6.1 6 2 0 7 7 7 0 Interferon-related developmental regulator (IFRD) bZIP_1 PF00170.21 KXS19740.1 - 0.0028 17.7 0.3 0.0028 17.7 0.3 3.5 3 1 1 4 4 4 2 bZIP transcription factor PKcGMP_CC PF16808.5 KXS19740.1 - 0.012 15.5 9.2 3.2 7.7 0.2 4.2 3 1 1 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase WD40_alt PF14077.6 KXS19740.1 - 0.041 13.8 1.0 4.3 7.3 0.0 3.5 3 0 0 3 3 3 0 Alternative WD40 repeat motif UPF0242 PF06785.11 KXS19740.1 - 0.14 12.2 0.4 0.14 12.2 0.4 2.6 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus TSC22 PF01166.18 KXS19740.1 - 0.26 11.6 4.2 0.49 10.8 0.1 2.9 3 1 0 3 3 3 0 TSC-22/dip/bun family Mto2_bdg PF12808.7 KXS19740.1 - 0.59 10.5 12.1 0.59 10.5 1.4 3.3 3 0 0 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Fib_alpha PF08702.10 KXS19740.1 - 0.92 9.7 5.0 0.96 9.6 0.7 2.7 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Med9 PF07544.13 KXS19740.1 - 1 9.5 7.9 0.57 10.3 0.5 2.8 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 SlyX PF04102.12 KXS19740.1 - 1.4 9.6 6.3 1.4 9.6 0.4 3.2 3 1 0 3 3 3 0 SlyX SIKE PF05769.11 KXS19740.1 - 1.4 8.8 0.0 1.4 8.8 0.0 3.1 3 0 0 3 3 3 0 SIKE family Noelin-1 PF12308.8 KXS19740.1 - 2.4 8.2 5.1 17 5.4 0.9 3.0 3 1 0 3 3 3 0 Neurogenesis glycoprotein APC_N_CC PF16689.5 KXS19740.1 - 5.1 7.2 8.6 0.18 11.9 0.6 2.7 3 1 0 3 3 3 0 Coiled-coil N-terminus of APC, dimerisation domain KfrA_N PF11740.8 KXS19740.1 - 7.2 7.3 10.2 19 6.0 5.6 2.7 2 2 0 2 2 2 0 Plasmid replication region DNA-binding N-term DivIC PF04977.15 KXS19740.1 - 9.9 6.0 10.5 20 5.0 0.1 3.7 3 2 1 4 4 4 0 Septum formation initiator Kinesin PF00225.23 KXS19741.1 - 8.1e-93 311.0 0.1 1e-92 310.6 0.1 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KXS19741.1 - 1.1e-17 64.3 0.9 1.3e-16 60.8 0.0 2.5 2 1 0 2 2 2 1 Microtubule binding Phage_F PF02305.17 KXS19741.1 - 0.034 12.9 0.2 0.14 10.9 0.2 1.8 2 0 0 2 2 2 0 Capsid protein (F protein) GSCFA PF08885.11 KXS19741.1 - 0.089 12.4 0.5 1 9.0 0.1 2.5 2 1 0 2 2 2 0 GSCFA family GRIP PF01465.20 KXS19742.1 - 3.4e-15 55.6 0.1 6.5e-15 54.8 0.1 1.5 1 0 0 1 1 1 1 GRIP domain Rab_bind PF16704.5 KXS19742.1 - 4.5e-05 23.4 4.1 4.5e-05 23.4 4.1 1.7 2 0 0 2 2 2 1 Rab binding domain SUB1_ProdP9 PF18213.1 KXS19742.1 - 0.082 12.8 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 SUB1 protease Prodomain ProdP9 DUF3584 PF12128.8 KXS19743.1 - 0.0014 16.2 17.1 0.0016 16.1 17.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) DUF4407 PF14362.6 KXS19743.1 - 0.011 15.1 16.1 0.0098 15.3 15.2 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) CENP-F_leu_zip PF10473.9 KXS19743.1 - 0.03 14.3 23.5 0.062 13.3 0.9 3.0 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GntR PF00392.21 KXS19743.1 - 0.053 13.2 1.3 0.45 10.2 0.1 2.4 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family DUF724 PF05266.14 KXS19743.1 - 0.34 10.7 16.7 0.41 10.4 8.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Spc7 PF08317.11 KXS19743.1 - 0.81 8.5 20.6 0.15 10.9 14.8 1.9 1 1 1 2 2 2 0 Spc7 kinetochore protein BORCS7 PF16088.5 KXS19743.1 - 0.84 9.9 8.8 5.2 7.4 0.3 2.7 1 1 2 3 3 3 0 BLOC-1-related complex sub-unit 7 Fez1 PF06818.15 KXS19743.1 - 1 9.8 18.4 0.08 13.4 3.4 2.2 1 1 1 2 2 2 0 Fez1 DUF4758 PF15950.5 KXS19743.1 - 1.5 9.2 4.3 0.74 10.2 0.8 1.9 1 1 1 2 2 2 0 Putative sperm flagellar membrane protein DUF2951 PF11166.8 KXS19743.1 - 1.6 9.0 5.1 0.43 10.8 0.4 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2951) CRR7 PF12095.8 KXS19743.1 - 1.9 9.0 5.0 31 5.1 0.9 2.8 2 1 0 2 2 2 0 Protein CHLORORESPIRATORY REDUCTION 7 ATG16 PF08614.11 KXS19743.1 - 1.9 8.7 26.3 1.8 8.7 17.0 2.7 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF572 PF04502.13 KXS19743.1 - 7.5 6.1 12.4 6.7 6.2 11.3 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF572) JIP_LZII PF16471.5 KXS19743.1 - 8.8 6.6 13.7 2.1 8.6 0.4 3.7 2 1 2 4 4 4 0 JNK-interacting protein leucine zipper II AAA_13 PF13166.6 KXS19743.1 - 8.9 4.8 15.2 11 4.6 15.2 1.1 1 0 0 1 1 1 0 AAA domain Cnn_1N PF07989.11 KXS19743.1 - 9.7 6.4 13.9 15 5.8 5.3 3.5 2 1 1 3 3 3 0 Centrosomin N-terminal motif 1 Plasmid_RAQPRD PF09686.10 KXS19743.1 - 9.8 6.5 11.8 0.41 10.9 1.5 3.1 2 1 1 3 3 3 0 Plasmid protein of unknown function (Plasmid_RAQPRD) YfzA PF14118.6 KXS19744.1 - 0.16 12.4 0.0 0.95 9.9 0.0 2.0 2 0 0 2 2 2 0 YfzA-like protein KASH_CCD PF14662.6 KXS19745.1 - 0.0052 16.6 13.2 0.008 16.0 13.2 1.1 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH Fez1 PF06818.15 KXS19745.1 - 0.0061 17.0 7.5 0.0091 16.5 7.5 1.1 1 0 0 1 1 1 1 Fez1 Syntaxin-6_N PF09177.11 KXS19745.1 - 0.013 16.1 0.5 0.021 15.3 0.5 1.3 1 0 0 1 1 1 0 Syntaxin 6, N-terminal FapA PF03961.13 KXS19745.1 - 0.024 13.2 2.5 0.033 12.8 2.5 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF2117 PF09890.9 KXS19745.1 - 0.062 12.8 0.5 0.091 12.2 0.5 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2117) GIT_CC PF16559.5 KXS19745.1 - 0.075 12.9 2.3 0.22 11.4 2.3 1.8 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor Spc7 PF08317.11 KXS19745.1 - 0.18 10.7 10.9 0.25 10.2 10.9 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Arfaptin PF06456.13 KXS19745.1 - 0.19 11.3 3.2 0.26 10.8 3.2 1.1 1 0 0 1 1 1 0 Arfaptin-like domain Atg14 PF10186.9 KXS19745.1 - 0.2 10.7 6.4 0.3 10.1 6.4 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 OmpH PF03938.14 KXS19745.1 - 1.1 9.6 12.8 2.1 8.7 12.8 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) RRM_1 PF00076.22 KXS19746.1 - 1.3e-68 226.7 0.0 1.6e-15 56.6 0.0 5.5 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KXS19746.1 - 6.7e-08 32.2 0.0 0.18 11.4 0.0 3.9 3 1 1 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KXS19746.1 - 0.00078 19.2 0.0 0.35 10.8 0.0 4.2 5 1 0 5 5 5 1 Occluded RNA-recognition motif Limkain-b1 PF11608.8 KXS19746.1 - 0.029 14.4 0.0 13 6.0 0.0 4.1 5 0 0 5 5 5 0 Limkain b1 SAM_2 PF07647.17 KXS19748.1 - 7.7e-08 32.3 0.1 1.3e-07 31.6 0.1 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KXS19748.1 - 0.00045 20.6 0.1 0.00068 20.0 0.1 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) IGR PF09597.10 KXS19748.1 - 0.03 14.4 0.1 0.061 13.4 0.1 1.4 1 0 0 1 1 1 0 IGR protein motif TB2_DP1_HVA22 PF03134.19 KXS19749.1 - 2e-15 56.5 1.2 3.2e-15 55.8 0.1 1.8 1 1 0 2 2 2 1 TB2/DP1, HVA22 family Vps5 PF09325.10 KXS19751.1 - 6.7e-55 186.2 5.0 9.8e-55 185.7 5.0 1.1 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 KXS19751.1 - 1.5e-20 73.3 0.0 1e-19 70.6 0.0 2.1 2 0 0 2 2 2 1 PX domain BAR_3_WASP_bdg PF10456.9 KXS19751.1 - 0.00081 18.9 1.2 0.017 14.6 1.2 2.1 1 1 0 1 1 1 1 WASP-binding domain of Sorting nexin protein COG2 PF06148.11 KXS19751.1 - 0.032 14.3 0.1 14 5.8 0.0 2.7 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 BAR PF03114.18 KXS19751.1 - 0.079 12.6 7.2 0.17 11.5 7.2 1.4 1 1 0 1 1 1 0 BAR domain TCTP PF00838.17 KXS19751.1 - 0.092 13.1 0.2 0.18 12.1 0.2 1.4 1 0 0 1 1 1 0 Translationally controlled tumour protein BAR_3 PF16746.5 KXS19751.1 - 0.13 11.9 4.6 0.65 9.7 4.7 1.8 1 1 0 1 1 1 0 BAR domain of APPL family ARD PF03079.14 KXS19751.1 - 0.16 12.2 0.7 0.25 11.5 0.7 1.3 1 0 0 1 1 1 0 ARD/ARD' family GvpL_GvpF PF06386.11 KXS19751.1 - 0.22 11.4 3.7 0.41 10.5 3.7 1.4 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF GrpE PF01025.19 KXS19751.1 - 0.53 9.9 4.3 1 9.0 4.3 1.4 1 0 0 1 1 1 0 GrpE HlyIII PF03006.20 KXS19752.1 - 1.5e-49 168.8 21.1 1.8e-49 168.5 21.1 1.1 1 0 0 1 1 1 1 Haemolysin-III related Prok-E2_C PF14459.6 KXS19752.1 - 0.066 13.4 0.3 0.12 12.5 0.3 1.4 1 0 0 1 1 1 0 Prokaryotic E2 family C AAA PF00004.29 KXS19753.1 - 3.3e-30 105.2 0.0 4.9e-30 104.7 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KXS19753.1 - 1.8e-07 31.7 0.0 3.6e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 KXS19753.1 - 1.7e-05 25.4 0.0 4e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KXS19753.1 - 2.2e-05 24.3 0.0 5.1e-05 23.1 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KXS19753.1 - 3.3e-05 24.2 0.1 0.00015 22.0 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 KXS19753.1 - 0.00019 21.1 0.0 0.014 15.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 KXS19753.1 - 0.00021 21.3 0.2 0.0056 16.6 0.2 2.1 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_14 PF13173.6 KXS19753.1 - 0.00031 20.8 0.1 0.00096 19.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KXS19753.1 - 0.00039 20.4 0.0 0.0011 19.0 0.0 1.9 2 0 0 2 2 1 1 AAA domain (dynein-related subfamily) DUF815 PF05673.13 KXS19753.1 - 0.0005 19.3 0.1 0.0087 15.2 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 KXS19753.1 - 0.00058 19.6 0.0 0.0014 18.4 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 KXS19753.1 - 0.0015 18.9 0.0 0.0043 17.4 0.0 1.9 1 0 0 1 1 1 1 RNA helicase IstB_IS21 PF01695.17 KXS19753.1 - 0.0021 17.8 0.1 0.01 15.6 0.0 2.0 3 0 0 3 3 2 1 IstB-like ATP binding protein Cytidylate_kin PF02224.18 KXS19753.1 - 0.0028 17.4 0.2 0.0064 16.3 0.2 1.7 1 1 0 1 1 1 1 Cytidylate kinase NACHT PF05729.12 KXS19753.1 - 0.0029 17.6 0.2 0.014 15.3 0.0 2.3 2 1 0 2 2 2 1 NACHT domain AAA_13 PF13166.6 KXS19753.1 - 0.0031 16.3 0.0 0.0037 16.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 KXS19753.1 - 0.0032 17.4 0.0 0.0082 16.1 0.0 1.6 2 0 0 2 2 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 KXS19753.1 - 0.0041 17.4 0.0 0.0086 16.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KXS19753.1 - 0.0049 16.7 0.1 0.011 15.6 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KXS19753.1 - 0.0051 17.0 0.2 0.012 15.8 0.2 1.8 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 KXS19753.1 - 0.0077 16.0 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 KXS19753.1 - 0.01 16.2 0.3 0.051 13.9 0.1 2.4 1 1 1 2 2 1 0 AAA domain AAA_7 PF12775.7 KXS19753.1 - 0.012 15.1 0.0 0.028 14.0 0.0 1.5 2 0 0 2 2 1 0 P-loop containing dynein motor region AAA_30 PF13604.6 KXS19753.1 - 0.015 15.0 0.0 0.035 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.14 KXS19753.1 - 0.015 15.4 0.0 0.071 13.2 0.0 2.1 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) PhoH PF02562.16 KXS19753.1 - 0.016 14.6 0.0 0.16 11.4 0.0 2.3 3 0 0 3 3 3 0 PhoH-like protein Sigma54_activat PF00158.26 KXS19753.1 - 0.018 14.8 0.0 0.037 13.7 0.0 1.6 1 1 0 1 1 1 0 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 KXS19753.1 - 0.022 14.9 0.0 0.078 13.1 0.0 2.0 1 1 1 2 2 2 0 Sigma-54 interaction domain AAA_17 PF13207.6 KXS19753.1 - 0.029 14.8 0.1 0.14 12.6 0.1 2.2 1 1 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 KXS19753.1 - 0.038 13.2 0.0 0.074 12.3 0.0 1.5 1 1 0 1 1 1 0 KAP family P-loop domain TIP49 PF06068.13 KXS19753.1 - 0.04 13.1 0.0 0.075 12.2 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain Mg_chelatase PF01078.21 KXS19753.1 - 0.042 13.2 0.0 0.1 12.0 0.0 1.7 2 0 0 2 2 1 0 Magnesium chelatase, subunit ChlI ABC_tran PF00005.27 KXS19753.1 - 0.055 14.0 0.0 0.088 13.3 0.0 1.4 1 0 0 1 1 1 0 ABC transporter PduV-EutP PF10662.9 KXS19753.1 - 0.072 12.8 0.1 0.25 11.1 0.0 1.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ATPase PF06745.13 KXS19753.1 - 0.074 12.4 0.1 0.5 9.7 0.0 2.1 1 1 0 2 2 2 0 KaiC DUF2075 PF09848.9 KXS19753.1 - 0.12 11.6 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Parvo_NS1 PF01057.17 KXS19753.1 - 0.13 11.3 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 SRP54 PF00448.22 KXS19753.1 - 0.13 11.8 0.0 0.41 10.2 0.0 1.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain MMR_HSR1 PF01926.23 KXS19753.1 - 0.14 12.2 0.2 0.38 10.9 0.0 1.8 2 0 0 2 2 1 0 50S ribosome-binding GTPase Rad17 PF03215.15 KXS19753.1 - 0.15 12.0 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain Polysacc_synt_4 PF04669.13 KXS19754.1 - 3.5e-20 72.4 0.3 3.2e-18 66.0 0.3 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis Peptidase_M16_M PF16187.5 KXS19755.1 - 5.5e-59 199.8 0.1 1.2e-58 198.6 0.0 1.6 2 0 0 2 2 2 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 KXS19755.1 - 9.9e-41 139.2 0.2 2.6e-40 137.8 0.0 1.8 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KXS19755.1 - 1.6e-30 106.5 0.0 1.8e-21 77.0 0.0 3.5 3 0 0 3 3 3 2 Peptidase M16 inactive domain Glyco_transf_24 PF18404.1 KXS19757.1 - 1.3e-147 490.4 0.9 2.1e-147 489.7 0.9 1.4 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 KXS19757.1 - 2.5e-56 191.5 0.0 8.3e-56 189.8 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 KXS19757.1 - 3.6e-38 130.0 0.0 6.9e-38 129.1 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Thioredoxin_12 PF18400.1 KXS19757.1 - 2e-36 125.6 0.0 3.7e-36 124.8 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_15 PF18403.1 KXS19757.1 - 3.5e-23 82.7 0.1 1.1e-18 67.9 0.1 2.4 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_13 PF18401.1 KXS19757.1 - 4.6e-22 78.4 0.0 1.3e-21 76.9 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like domain Glyco_transf_8 PF01501.20 KXS19757.1 - 2.2e-05 24.2 0.0 4.1e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 8 Methyltransf_25 PF13649.6 KXS19758.1 - 4.2e-08 33.8 0.0 2.6e-07 31.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 KXS19758.1 - 1.3e-07 31.3 0.0 2e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 KXS19758.1 - 2.2e-06 28.2 0.0 1.2e-05 25.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 KXS19758.1 - 5.2e-06 26.1 0.0 8.6e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 KXS19758.1 - 2.3e-05 25.1 0.0 0.00018 22.2 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain PRMT5 PF05185.16 KXS19758.1 - 7e-05 22.7 0.0 0.00013 21.9 0.0 1.4 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase CMAS PF02353.20 KXS19758.1 - 0.0014 18.0 0.3 0.046 13.0 0.0 2.2 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 KXS19758.1 - 0.0031 17.4 0.0 0.0096 15.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXS19758.1 - 0.0038 17.0 0.0 0.007 16.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 KXS19758.1 - 0.026 13.9 0.0 0.04 13.3 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB Cons_hypoth95 PF03602.15 KXS19758.1 - 0.037 13.7 0.0 0.055 13.1 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 DREV PF05219.12 KXS19758.1 - 0.08 12.0 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_9 PF08003.11 KXS19758.1 - 0.089 11.7 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Xpo1 PF08389.12 KXS19759.1 - 0.0097 16.0 1.6 0.021 14.9 1.6 1.5 1 0 0 1 1 1 1 Exportin 1-like protein Dopey_N PF04118.14 KXS19759.1 - 0.028 13.5 0.3 0.044 12.9 0.3 1.2 1 0 0 1 1 1 0 Dopey, N-terminal PHAT PF09246.10 KXS19759.1 - 0.075 12.9 0.2 8.2 6.3 0.0 2.6 2 0 0 2 2 2 0 PHAT Fib_alpha PF08702.10 KXS19759.1 - 0.16 12.1 0.3 0.42 10.8 0.2 1.7 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Sec6 PF06046.13 KXS19759.1 - 0.2 10.0 1.4 0.3 9.4 1.4 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec6 HEAT PF02985.22 KXS19759.1 - 0.24 11.8 1.4 4.5 7.8 0.1 3.7 4 0 0 4 4 4 0 HEAT repeat Hrs_helical PF12210.8 KXS19759.1 - 0.38 11.3 1.6 0.91 10.1 1.6 1.6 1 0 0 1 1 1 0 Hepatocyte growth factor-regulated tyrosine kinase substrate DUF2043 PF09740.9 KXS19760.1 - 1.2e-23 83.8 0.0 4.9e-23 81.8 0.0 1.9 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2043) TAF6_C PF07571.13 KXS19760.1 - 0.12 12.7 0.1 0.23 11.8 0.1 1.6 1 1 0 1 1 1 0 TAF6 C-terminal HEAT repeat domain BORCS8 PF10167.9 KXS19761.1 - 9.8e-13 48.0 0.0 1.1e-12 47.9 0.0 1.0 1 0 0 1 1 1 1 BLOC-1-related complex sub-unit 8 CLAMP PF14769.6 KXS19762.1 - 1.5e-32 112.0 6.1 2.5e-32 111.3 6.1 1.4 1 0 0 1 1 1 1 Flagellar C1a complex subunit C1a-32 COPI_C PF06957.11 KXS19763.1 - 4.9e-148 493.2 0.0 6.2e-148 492.9 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus Coatomer_WDAD PF04053.14 KXS19763.1 - 4.7e-134 447.8 0.0 6.8e-134 447.3 0.0 1.2 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.32 KXS19763.1 - 3.7e-44 147.8 18.7 1.2e-07 32.3 0.3 8.8 9 0 0 9 9 9 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXS19763.1 - 4.3e-14 52.6 0.8 7.4e-06 26.2 0.0 6.1 4 1 3 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KXS19763.1 - 0.05 12.2 6.1 2.2 6.8 0.1 3.4 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Prok-RING_1 PF14446.6 KXS19763.1 - 1.5 8.8 5.3 0.74 9.8 0.9 2.6 2 1 1 3 3 3 0 Prokaryotic RING finger family 1 SHMT PF00464.19 KXS19764.1 - 8.2e-181 600.9 0.0 9.7e-181 600.7 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.21 KXS19764.1 - 0.00011 21.6 0.0 0.00038 19.8 0.0 1.8 1 1 0 1 1 1 1 Beta-eliminating lyase HrpB1_HrpK PF09613.10 KXS19764.1 - 0.057 13.1 0.0 0.16 11.6 0.0 1.7 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB1_HrpK) AbiJ_NTD3 PF18860.1 KXS19764.1 - 0.076 12.5 0.0 0.48 9.9 0.0 2.1 2 0 0 2 2 2 0 AbiJ N-terminal domain 3 DegT_DnrJ_EryC1 PF01041.17 KXS19764.1 - 0.13 11.6 0.0 0.5 9.6 0.0 1.9 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family AAA PF00004.29 KXS19765.1 - 2.8e-43 147.5 0.0 4.2e-43 146.9 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KXS19765.1 - 2.8e-08 34.1 1.7 0.00015 22.0 0.0 3.1 1 1 1 3 3 3 1 AAA domain RuvB_N PF05496.12 KXS19765.1 - 3.5e-07 30.1 0.0 6.8e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KXS19765.1 - 1.3e-06 28.4 0.2 9.7e-06 25.6 0.2 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KXS19765.1 - 3.8e-06 27.1 0.0 5.9e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 KXS19765.1 - 1.6e-05 24.3 0.0 3.7e-05 23.1 0.0 1.5 1 1 0 1 1 1 1 TIP49 P-loop domain AAA_16 PF13191.6 KXS19765.1 - 2e-05 25.1 2.1 0.0016 18.9 0.1 2.7 1 1 2 3 3 3 1 AAA ATPase domain DUF815 PF05673.13 KXS19765.1 - 6.3e-05 22.3 0.0 0.00011 21.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_25 PF13481.6 KXS19765.1 - 8.7e-05 22.2 1.3 0.02 14.5 0.1 2.7 1 1 2 3 3 3 1 AAA domain IstB_IS21 PF01695.17 KXS19765.1 - 0.0001 22.1 0.0 0.00019 21.2 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein TniB PF05621.11 KXS19765.1 - 0.00012 21.5 0.1 0.26 10.7 0.1 2.5 1 1 1 2 2 2 2 Bacterial TniB protein AAA_lid_3 PF17862.1 KXS19765.1 - 0.00024 20.9 0.0 0.00077 19.2 0.0 1.9 1 0 0 1 1 1 1 AAA+ lid domain AAA_14 PF13173.6 KXS19765.1 - 0.00052 20.0 0.0 0.00095 19.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain Vps4_C PF09336.10 KXS19765.1 - 0.0011 18.9 0.2 0.0056 16.7 0.0 2.3 3 0 0 3 3 2 1 Vps4 C terminal oligomerisation domain Mg_chelatase PF01078.21 KXS19765.1 - 0.0013 18.1 0.2 0.0035 16.8 0.1 1.6 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 KXS19765.1 - 0.0014 18.8 0.0 0.0045 17.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KXS19765.1 - 0.0016 19.0 0.0 0.0047 17.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KXS19765.1 - 0.0021 18.3 0.0 0.0034 17.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 KXS19765.1 - 0.0047 16.9 0.1 0.057 13.3 0.0 2.2 1 1 0 2 2 2 1 NACHT domain AAA_7 PF12775.7 KXS19765.1 - 0.0065 16.0 0.0 0.017 14.6 0.0 1.7 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_19 PF13245.6 KXS19765.1 - 0.015 15.6 0.0 0.031 14.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KXS19765.1 - 0.015 15.0 0.0 0.033 13.9 0.0 1.5 1 1 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 KXS19765.1 - 0.02 14.6 0.1 0.091 12.5 0.1 2.1 1 1 0 1 1 1 0 Sigma-54 interaction domain ATPase PF06745.13 KXS19765.1 - 0.022 14.1 0.5 1.6 8.0 0.1 2.2 1 1 1 2 2 2 0 KaiC PhoH PF02562.16 KXS19765.1 - 0.026 14.0 0.1 0.062 12.7 0.1 1.5 1 1 0 1 1 1 0 PhoH-like protein RNA_helicase PF00910.22 KXS19765.1 - 0.032 14.6 0.0 0.06 13.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_30 PF13604.6 KXS19765.1 - 0.036 13.8 0.1 0.089 12.5 0.1 1.6 1 1 0 1 1 1 0 AAA domain Guanylate_kin PF00625.21 KXS19765.1 - 0.042 13.5 0.1 0.29 10.8 0.0 2.2 1 1 0 2 2 2 0 Guanylate kinase MCM PF00493.23 KXS19765.1 - 0.048 12.7 0.0 0.072 12.2 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain AAA_11 PF13086.6 KXS19765.1 - 0.088 12.6 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KXS19765.1 - 0.093 12.7 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 KXS19765.1 - 0.13 12.7 0.0 0.32 11.5 0.0 1.6 1 1 0 1 1 1 0 ABC transporter Bac_DnaA PF00308.18 KXS19765.1 - 0.15 11.9 0.0 0.29 10.9 0.0 1.5 1 1 0 1 1 1 0 Bacterial dnaA protein CPT PF07931.12 KXS19765.1 - 0.15 11.9 0.1 0.54 10.1 0.0 1.8 1 1 1 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_17 PF13207.6 KXS19765.1 - 0.17 12.3 0.2 1.3 9.4 0.0 2.1 1 1 1 2 2 2 0 AAA domain ATPase_2 PF01637.18 KXS19765.1 - 0.17 11.7 0.0 1.5 8.6 0.0 2.2 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea JAB PF01398.21 KXS19766.1 - 5.7e-34 116.6 0.4 1.2e-33 115.6 0.0 1.7 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 KXS19766.1 - 1.2e-13 51.5 1.9 2.1e-13 50.7 1.9 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 KXS19766.1 - 2.1e-06 27.5 0.0 4e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain DUF5624 PF18538.1 KXS19766.1 - 0.0096 16.0 0.7 0.018 15.1 0.7 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5624) MCM PF00493.23 KXS19767.1 - 7e-84 280.4 0.0 1e-83 279.8 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_lid PF17855.1 KXS19767.1 - 4.4e-28 97.5 1.4 8.8e-28 96.6 1.4 1.5 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_OB PF17207.3 KXS19767.1 - 7.1e-26 90.5 2.6 1.4e-25 89.6 2.6 1.5 1 0 0 1 1 1 1 MCM OB domain Mg_chelatase PF01078.21 KXS19767.1 - 6.9e-05 22.3 0.1 0.00021 20.7 0.0 1.8 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KXS19767.1 - 7.7e-05 22.6 0.0 0.00015 21.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KXS19767.1 - 0.00017 21.6 0.0 0.0006 19.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_lid_2 PF17863.1 KXS19767.1 - 0.045 13.6 0.2 0.1 12.4 0.2 1.6 1 0 0 1 1 1 0 AAA lid domain Methyltransf_16 PF10294.9 KXS19768.1 - 1.6e-13 50.7 0.0 2.2e-12 47.1 0.0 2.0 1 1 0 1 1 1 1 Lysine methyltransferase ADIP PF11559.8 KXS19769.1 - 1.2 9.3 5.3 3.2 7.8 4.5 1.9 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Acetyltransf_4 PF13420.7 KXS19770.1 - 1.8e-23 83.4 0.0 2.3e-23 83.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KXS19770.1 - 2.3e-09 38.1 0.0 3.1e-09 37.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXS19770.1 - 2.8e-09 37.2 0.1 3.7e-09 36.8 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXS19770.1 - 4.8e-06 26.9 0.2 8.2e-06 26.2 0.2 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KXS19770.1 - 2.6e-05 24.1 0.0 3.8e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXS19770.1 - 0.00017 21.4 0.0 0.0003 20.7 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein PCI PF01399.27 KXS19771.1 - 7.7e-06 26.4 0.0 1.5e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 PCI domain CSN7a_helixI PF18392.1 KXS19771.1 - 0.003 17.4 0.2 0.0049 16.7 0.2 1.3 1 0 0 1 1 1 1 COP9 signalosome complex subunit 7a helix I domain HLH PF00010.26 KXS19773.1 - 2.6e-10 40.1 0.4 5.6e-10 39.0 0.4 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Vir_act_alpha_C PF10400.9 KXS19773.1 - 0.28 11.9 3.0 0.59 10.9 3.0 1.4 1 0 0 1 1 1 0 Virulence activator alpha C-term Skp1_POZ PF03931.15 KXS19774.1 - 2.2e-05 24.5 0.0 4.1e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain zinc_ribbon_10 PF10058.9 KXS19775.1 - 6.3e-12 45.0 0.0 1.1e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein tRNA_anti-like PF12869.7 KXS19775.1 - 0.038 13.6 0.0 0.056 13.1 0.0 1.2 1 0 0 1 1 1 0 tRNA_anti-like Pex14_N PF04695.13 KXS19775.1 - 1.5 9.5 6.5 2.4 8.8 6.5 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DFP PF04127.15 KXS19776.1 - 8.7e-17 61.5 0.0 1.1e-08 35.1 0.0 2.2 2 0 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein Phage_sheath_1 PF04984.14 KXS19776.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Phage tail sheath protein subtilisin-like domain DNA_binding_1 PF01035.20 KXS19777.1 - 8.3e-24 83.5 0.2 9.9e-24 83.3 0.2 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Helicase_C PF00271.31 KXS19779.1 - 1.6e-10 41.3 0.0 4.4e-09 36.7 0.0 2.3 1 1 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 KXS19779.1 - 9.3e-09 34.5 0.0 1.2e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain VIGSSK PF14773.6 KXS19779.1 - 1.9e-05 24.7 0.2 3.9e-05 23.7 0.2 1.5 1 0 0 1 1 1 1 Helicase-associated putative binding domain, C-terminal TMF_DNA_bd PF12329.8 KXS19780.1 - 0.0014 18.6 2.2 0.0014 18.6 2.2 11.4 8 3 3 11 11 11 3 TATA element modulatory factor 1 DNA binding APOBEC4 PF18775.1 KXS19780.1 - 0.057 13.6 0.0 0.43 10.8 0.0 2.3 2 0 0 2 2 2 0 APOBEC4 DEAD PF00270.29 KXS19782.1 - 5.9e-44 149.9 0.0 4.6e-43 147.0 0.0 2.4 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXS19782.1 - 1.3e-30 106.0 0.0 5e-30 104.1 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXS19782.1 - 0.00013 22.1 0.0 0.0011 19.1 0.0 2.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.14 KXS19782.1 - 0.025 13.9 0.0 0.048 12.9 0.0 1.5 1 0 0 1 1 1 0 SecA DEAD-like domain UTP25 PF06862.12 KXS19782.1 - 0.036 12.8 0.0 0.23 10.2 0.0 1.9 1 1 1 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 AAA_22 PF13401.6 KXS19782.1 - 0.13 12.5 0.4 25 5.2 0.0 3.6 4 0 0 4 4 4 0 AAA domain zf-CCHC_4 PF14392.6 KXS19782.1 - 0.22 11.3 4.0 0.093 12.5 0.8 2.1 3 0 0 3 3 3 0 Zinc knuckle Hydrolase_4 PF12146.8 KXS19783.1 - 9.5e-11 41.4 0.0 1.6e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KXS19783.1 - 2.6e-08 33.8 0.0 3.4e-07 30.2 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXS19783.1 - 1.5e-07 32.2 0.6 2.5e-07 31.6 0.6 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DNApol_Exo PF18136.1 KXS19784.1 - 2.4e-83 279.6 0.0 5.3e-83 278.4 0.0 1.6 1 0 0 1 1 1 1 DNA mitochondrial polymerase exonuclease domain DNA_pol_A PF00476.20 KXS19784.1 - 7e-40 137.2 0.0 1.4e-39 136.2 0.0 1.4 2 0 0 2 2 2 1 DNA polymerase family A G-patch PF01585.23 KXS19785.1 - 8.2e-07 28.8 0.6 8.2e-07 28.8 0.6 2.8 4 0 0 4 4 4 1 G-patch domain ELO PF01151.18 KXS19787.1 - 7.5e-07 28.9 0.8 8.9e-07 28.7 0.8 1.2 1 0 0 1 1 1 1 GNS1/SUR4 family BRCA-2_helical PF09169.10 KXS19788.1 - 1e-11 44.8 0.2 2.2e-11 43.8 0.2 1.5 1 1 0 1 1 1 1 BRCA2, helical BRCA-2_OB1 PF09103.10 KXS19788.1 - 0.0091 15.9 0.0 0.018 15.0 0.0 1.5 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 Erf4 PF10256.9 KXS19789.1 - 6e-13 48.9 0.0 5.9e-10 39.3 0.0 2.1 2 0 0 2 2 2 2 Golgin subfamily A member 7/ERF4 family Solute_trans_a PF03619.16 KXS19790.1 - 3.1e-91 305.6 13.0 3.8e-91 305.3 13.0 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha RNA_pol_Rpb2_6 PF00562.28 KXS19791.1 - 2.4e-129 431.8 0.1 3.3e-129 431.4 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KXS19791.1 - 2.5e-61 206.8 0.1 3.7e-61 206.2 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 KXS19791.1 - 5.2e-44 150.1 0.0 1.5e-43 148.7 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 KXS19791.1 - 7.7e-34 116.0 0.0 2e-33 114.6 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 KXS19791.1 - 1.3e-26 92.6 0.0 3.4e-26 91.2 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.13 KXS19791.1 - 1e-23 83.4 1.7 1.1e-23 83.3 0.2 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.17 KXS19791.1 - 1.9e-16 60.4 0.1 4.5e-16 59.1 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 MRNIP PF15749.5 KXS19791.1 - 0.065 14.0 0.1 0.17 12.6 0.1 1.6 1 0 0 1 1 1 0 MRN-interacting protein C1_2 PF03107.16 KXS19791.1 - 0.21 11.9 0.5 0.44 10.9 0.5 1.4 1 0 0 1 1 1 0 C1 domain mRNA_cap_enzyme PF01331.19 KXS19792.1 - 9.8e-30 103.8 0.0 7.2e-18 65.1 0.0 2.1 1 1 1 2 2 2 2 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 KXS19792.1 - 8.1e-22 77.9 0.0 1.4e-21 77.2 0.0 1.4 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.21 KXS19792.1 - 3.8e-07 30.0 0.0 4.3e-05 23.2 0.0 2.4 1 1 1 2 2 2 2 ATP dependent DNA ligase domain TPR_14 PF13428.6 KXS19793.1 - 1.7e-11 43.9 12.4 0.00036 21.1 0.3 7.3 3 2 4 7 7 7 3 Tetratricopeptide repeat Suf PF05843.14 KXS19793.1 - 1.4e-09 38.4 5.4 1.9e-06 28.1 0.1 4.1 2 2 2 4 4 4 2 Suppressor of forked protein (Suf) TPR_19 PF14559.6 KXS19793.1 - 9.4e-07 29.3 2.2 0.00062 20.2 0.3 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KXS19793.1 - 1.6e-05 25.4 10.3 0.23 12.2 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 KXS19793.1 - 5.6e-05 23.3 0.3 0.14 12.5 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KXS19793.1 - 0.00098 18.6 0.4 0.0018 17.7 0.4 1.3 1 0 0 1 1 1 1 MalT-like TPR region TPR_15 PF13429.6 KXS19793.1 - 0.0033 16.7 2.6 4.4 6.4 0.0 3.7 2 2 1 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 KXS19793.1 - 0.013 16.1 5.8 0.15 12.8 0.0 4.3 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 KXS19793.1 - 0.063 13.0 0.0 8.6 6.1 0.0 2.8 1 1 1 2 2 2 0 TPR repeat TPR_8 PF13181.6 KXS19793.1 - 0.096 12.9 0.0 16 6.0 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 KXS19793.1 - 0.24 11.5 0.8 4.9 7.4 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 KXS19793.1 - 0.61 10.0 0.1 0.61 10.0 0.1 3.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_9 PF13371.6 KXS19793.1 - 1.1 9.4 7.2 1.8 8.7 0.4 4.2 4 1 1 5 5 5 0 Tetratricopeptide repeat Glyco_transf_22 PF03901.17 KXS19794.1 - 5.5e-39 134.6 12.6 8.2e-39 134.0 12.6 1.2 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family PAXNEB PF05625.11 KXS19794.1 - 0.34 10.0 0.5 0.49 9.5 0.0 1.4 2 0 0 2 2 2 0 PAXNEB protein Cullin PF00888.22 KXS19795.1 - 0.0012 17.5 0.0 0.0014 17.4 0.0 1.1 1 0 0 1 1 1 1 Cullin family PH PF00169.29 KXS19796.1 - 3.4e-05 24.3 0.0 4.5e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 KXS19796.1 - 0.019 15.2 0.0 0.024 14.9 0.0 1.2 1 0 0 1 1 1 0 Pleckstrin homology domain UCH PF00443.29 KXS19797.1 - 2e-39 135.6 0.0 2.8e-39 135.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KXS19797.1 - 8.5e-16 58.0 4.9 1.9e-15 56.9 4.9 1.6 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 KXS19797.1 - 7.2e-14 52.1 1.8 0.00015 21.5 0.0 4.1 4 0 0 4 4 4 3 Ubiquitin carboxyl-terminal hydrolase YqzE PF14038.6 KXS19797.1 - 0.77 9.8 3.0 0.97 9.5 0.2 2.4 2 0 0 2 2 2 0 YqzE-like protein Pkinase PF00069.25 KXS19798.1 - 2e-68 230.6 0.0 2.6e-68 230.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS19798.1 - 4.2e-48 163.9 0.0 7.2e-48 163.1 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXS19798.1 - 0.0022 17.4 0.0 0.0051 16.2 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KXS19798.1 - 0.003 16.4 0.0 0.0044 15.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase YrbL-PhoP_reg PF10707.9 KXS19798.1 - 0.0055 16.3 0.1 0.0077 15.8 0.1 1.2 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL APH PF01636.23 KXS19798.1 - 0.092 12.6 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 KXS19798.1 - 0.15 11.4 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family JAB PF01398.21 KXS19799.1 - 3.8e-18 65.6 0.0 9.1e-18 64.4 0.0 1.6 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease BRCC36_C PF18110.1 KXS19799.1 - 5.8e-09 36.0 0.0 1.2e-08 35.0 0.0 1.6 1 0 0 1 1 1 1 BRCC36 C-terminal helical domain Prok-JAB PF14464.6 KXS19799.1 - 1.6e-06 27.9 0.0 2.9e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain PTPLA PF04387.14 KXS19800.1 - 8.1e-52 175.3 5.2 8.1e-52 175.3 5.2 1.7 2 0 0 2 2 2 1 Protein tyrosine phosphatase-like protein, PTPLA RasGAP PF00616.19 KXS19801.1 - 2.3e-21 76.5 14.4 1.8e-17 63.8 0.7 3.4 2 1 1 3 3 3 2 GTPase-activator protein for Ras-like GTPase C2 PF00168.30 KXS19801.1 - 3.2e-14 53.1 0.0 1.3e-13 51.1 0.0 2.1 2 0 0 2 2 2 1 C2 domain FCH PF00611.23 KXS19801.1 - 1.2e-07 31.9 0.2 1.2e-07 31.9 0.2 2.5 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain PH PF00169.29 KXS19801.1 - 3.4e-06 27.5 0.1 1.7e-05 25.3 0.0 2.3 2 0 0 2 2 2 1 PH domain Syntaxin_2 PF14523.6 KXS19801.1 - 0.071 13.5 7.8 0.3 11.5 7.1 2.5 2 0 0 2 2 2 0 Syntaxin-like protein FapA PF03961.13 KXS19801.1 - 0.08 11.5 3.9 0.16 10.6 3.9 1.4 1 0 0 1 1 1 0 Flagellar Assembly Protein A EMP24_GP25L PF01105.24 KXS19801.1 - 2.2 8.2 6.8 0.57 10.1 2.9 2.1 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD ZapA PF05164.13 KXS19801.1 - 2.7 8.5 7.8 0.68 10.4 0.4 2.9 3 0 0 3 3 3 0 Cell division protein ZapA SLX9 PF15341.6 KXS19801.1 - 4 7.8 11.2 17 5.8 5.5 2.8 2 0 0 2 2 2 0 Ribosome biogenesis protein SLX9 Glyco_hydro_5_C PF18564.1 KXS19803.1 - 4.2e-12 46.4 0.1 9.4e-12 45.3 0.1 1.6 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain Cellulase PF00150.18 KXS19803.1 - 6.6e-12 45.4 0.0 1.6e-08 34.4 0.0 3.1 3 0 0 3 3 3 3 Cellulase (glycosyl hydrolase family 5) Methyltransf_16 PF10294.9 KXS19806.1 - 1.4e-07 31.4 0.0 9.4e-07 28.7 0.0 2.0 2 0 0 2 2 2 1 Lysine methyltransferase Methyltransf_25 PF13649.6 KXS19806.1 - 0.0022 18.6 0.4 1.1 10.0 0.0 2.8 2 0 0 2 2 2 2 Methyltransferase domain MTS PF05175.14 KXS19806.1 - 0.045 13.3 0.3 0.2 11.2 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase small domain PrmA PF06325.13 KXS19806.1 - 3.4 7.0 4.3 1.2 8.5 0.0 1.9 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Cofilin_ADF PF00241.20 KXS19807.1 - 9e-10 38.4 0.0 1.1e-09 38.1 0.0 1.2 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein ABC_tran PF00005.27 KXS19808.1 - 1.3e-20 74.3 0.0 2e-20 73.7 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KXS19808.1 - 1.9e-05 24.7 0.0 0.0025 17.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KXS19808.1 - 0.0016 18.7 0.0 0.0031 17.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KXS19808.1 - 0.0017 18.1 0.1 0.003 17.3 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KXS19808.1 - 0.0024 18.3 0.1 0.0058 17.0 0.1 1.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.6 KXS19808.1 - 0.019 14.7 0.0 0.027 14.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 KXS19808.1 - 0.028 13.7 0.0 0.038 13.2 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain Zeta_toxin PF06414.12 KXS19808.1 - 0.028 13.7 0.0 0.043 13.1 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.6 KXS19808.1 - 0.031 14.8 0.1 0.063 13.8 0.1 1.5 2 0 0 2 2 1 0 AAA domain APS_kinase PF01583.20 KXS19808.1 - 0.034 14.0 0.1 0.055 13.4 0.1 1.2 1 0 0 1 1 1 0 Adenylylsulphate kinase SMC_N PF02463.19 KXS19808.1 - 0.041 13.3 0.1 0.81 9.1 0.0 2.1 1 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain Rad17 PF03215.15 KXS19808.1 - 0.097 12.6 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_29 PF13555.6 KXS19808.1 - 0.099 12.4 0.1 0.23 11.2 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain NACHT PF05729.12 KXS19808.1 - 0.13 12.2 0.2 0.29 11.1 0.2 1.5 1 0 0 1 1 1 0 NACHT domain AAA_33 PF13671.6 KXS19808.1 - 0.18 12.0 0.1 0.36 11.0 0.1 1.5 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 KXS19808.1 - 0.19 11.3 0.1 0.75 9.4 0.2 1.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain SbcCD_C PF13558.6 KXS19808.1 - 0.19 12.0 0.2 2.4 8.5 0.2 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA PF00004.29 KXS19808.1 - 0.23 11.9 0.1 1.4 9.3 0.2 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Y_phosphatase PF00102.27 KXS19809.1 - 1.4e-53 181.8 0.0 1.1e-46 159.3 0.0 3.4 2 1 0 2 2 2 2 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 KXS19809.1 - 0.022 14.8 0.0 0.037 14.0 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family DSPc PF00782.20 KXS19809.1 - 0.027 14.3 0.1 0.048 13.5 0.1 1.3 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 KXS19809.1 - 0.03 14.4 0.0 0.048 13.8 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate Topoisom_bac PF01131.20 KXS19810.1 - 2.8e-98 329.6 0.0 3.4e-98 329.4 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 KXS19810.1 - 6.4e-18 64.9 0.0 1.1e-17 64.2 0.0 1.4 1 0 0 1 1 1 1 Toprim domain DUF953 PF06110.11 KXS19810.1 - 0.018 14.6 0.3 0.048 13.3 0.1 1.7 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF953) Pkinase_Tyr PF07714.17 KXS19813.1 - 2.1e-27 96.0 0.0 3.2e-27 95.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXS19813.1 - 1.5e-23 83.5 0.0 2.4e-23 82.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Ank_2 PF12796.7 KXS19813.1 - 7.4e-16 58.5 0.5 4.4e-08 33.6 0.0 2.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXS19813.1 - 4.9e-14 52.2 0.9 2.3e-11 43.7 0.2 2.9 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXS19813.1 - 8.3e-11 42.2 0.1 3.2e-06 27.6 0.0 3.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KXS19813.1 - 3e-07 30.6 0.1 0.00039 20.7 0.0 3.5 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 KXS19813.1 - 3.3e-06 27.0 0.2 0.00093 19.5 0.0 3.7 3 0 0 3 3 3 1 Ankyrin repeat Anp1 PF03452.14 KXS19814.1 - 3.3e-25 89.0 0.0 4e-25 88.7 0.0 1.1 1 0 0 1 1 1 1 Anp1 Y_phosphatase PF00102.27 KXS19815.1 - 6.5e-16 58.6 0.0 9.6e-16 58.1 0.0 1.2 1 1 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 KXS19815.1 - 0.029 14.2 0.0 0.05 13.4 0.0 1.4 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 KXS19815.1 - 0.052 13.7 0.0 0.086 13.0 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 KXS19815.1 - 0.065 13.2 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family Y_phosphatase PF00102.27 KXS19816.1 - 0.007 16.0 0.0 0.0085 15.7 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Bac_surface_Ag PF01103.23 KXS19816.1 - 0.016 14.8 0.4 0.02 14.4 0.4 1.1 1 0 0 1 1 1 0 Surface antigen WD40 PF00400.32 KXS19819.1 - 6.6e-16 58.4 5.9 0.00013 22.6 0.0 5.5 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXS19819.1 - 8.4e-06 26.0 0.1 2.7 8.3 0.0 4.0 3 1 0 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KXS19819.1 - 0.1 11.2 0.0 0.28 9.8 0.0 1.7 3 0 0 3 3 3 0 Nucleoporin Nup120/160 Hira PF07569.11 KXS19819.1 - 0.1 12.3 0.1 0.68 9.6 0.0 2.0 2 0 0 2 2 2 0 TUP1-like enhancer of split BUD22 PF09073.10 KXS19819.1 - 0.26 10.6 40.0 0.97 8.7 26.7 2.1 2 0 0 2 2 2 0 BUD22 adh_short_C2 PF13561.6 KXS19820.1 - 3e-50 170.9 0.0 4.1e-50 170.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXS19820.1 - 6.7e-40 136.6 0.0 9.1e-40 136.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXS19820.1 - 4.3e-07 30.0 0.0 6e-07 29.5 0.0 1.1 1 0 0 1 1 1 1 KR domain TnpW PF14202.6 KXS19820.1 - 0.11 12.4 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 Transposon-encoded protein TnpW NTP_transf_9 PF04248.12 KXS19820.1 - 0.17 11.8 0.0 0.41 10.6 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF427) Mito_carr PF00153.27 KXS19822.1 - 9.6e-69 227.4 0.0 3.9e-23 81.2 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein MaoC_dehydrat_N PF13452.6 KXS19825.1 - 0.074 13.2 0.0 0.65 10.1 0.0 2.2 2 0 0 2 2 2 0 N-terminal half of MaoC dehydratase MaoC_dehydratas PF01575.19 KXS19825.1 - 0.13 11.9 0.0 0.27 10.8 0.0 1.6 1 0 0 1 1 1 0 MaoC like domain NUC194 PF08163.12 KXS19826.1 - 1.3e-33 116.5 0.1 8.1e-32 110.6 0.0 2.4 2 0 0 2 2 2 1 NUC194 domain PI3_PI4_kinase PF00454.27 KXS19826.1 - 2.8e-20 73.2 0.0 7.8e-20 71.7 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Fes1 PF08609.10 KXS19826.1 - 2.2e-16 60.5 0.6 1.1e-15 58.2 0.2 2.6 2 0 0 2 2 2 1 Nucleotide exchange factor Fes1 FAT PF02259.23 KXS19826.1 - 2.1e-06 27.2 0.0 5e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 FAT domain HEAT_2 PF13646.6 KXS19826.1 - 0.00032 21.0 0.6 0.026 14.9 0.0 3.7 3 0 0 3 3 3 1 HEAT repeats HEAT_EZ PF13513.6 KXS19826.1 - 0.0013 19.2 1.3 0.03 14.8 0.4 3.9 3 0 0 3 3 3 1 HEAT-like repeat HEAT PF02985.22 KXS19826.1 - 0.0013 18.8 1.9 39 4.9 0.0 5.7 4 0 0 4 4 4 0 HEAT repeat Arm PF00514.23 KXS19826.1 - 0.13 12.3 0.7 14 5.9 0.1 4.2 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Pkinase PF00069.25 KXS19828.1 - 2.1e-58 197.8 0.0 3.9e-58 196.9 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS19828.1 - 1.3e-47 162.3 0.0 1.8e-47 161.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXS19828.1 - 4.3e-06 25.8 0.0 7.1e-06 25.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Apolipoprotein PF01442.18 KXS19828.1 - 0.00022 21.2 0.1 0.00065 19.6 0.0 1.8 2 0 0 2 2 2 1 Apolipoprotein A1/A4/E domain Kinase-like PF14531.6 KXS19828.1 - 0.00084 18.7 0.0 0.0015 17.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like DUF3498 PF12004.8 KXS19828.1 - 0.37 9.9 2.6 0.62 9.2 2.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3498) LZ_Tnp_IS66 PF13007.7 KXS19830.1 - 0.098 13.5 2.7 0.56 11.0 0.1 2.8 2 1 1 3 3 3 0 Transposase C of IS166 homeodomain zf-C2H2 PF00096.26 KXS19831.1 - 0.02 15.3 1.1 0.02 15.3 1.1 2.9 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXS19831.1 - 0.07 14.0 1.2 0.07 14.0 1.2 3.6 4 0 0 4 4 4 0 C2H2-type zinc finger adh_short PF00106.25 KXS19833.1 - 2.1e-33 115.5 0.2 1.7e-32 112.4 0.2 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXS19833.1 - 4.3e-22 78.8 0.1 1.2e-21 77.4 0.1 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXS19833.1 - 1.3e-07 31.7 0.2 2.2e-07 30.9 0.2 1.3 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.20 KXS19833.1 - 0.014 15.5 0.2 0.023 14.7 0.2 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 KXS19833.1 - 0.084 13.1 0.1 0.16 12.2 0.1 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 KXS19833.1 - 0.11 11.9 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Aminotran_5 PF00266.19 KXS19834.1 - 2.1e-33 115.8 0.0 3.2e-31 108.6 0.0 3.6 1 1 0 1 1 1 1 Aminotransferase class-V Hexapep PF00132.24 KXS19835.1 - 1.6e-08 34.0 3.9 0.0022 17.6 0.0 4.3 3 1 1 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Zn_clus PF00172.18 KXS19839.1 - 7e-09 35.7 14.0 9.9e-09 35.2 14.0 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Rep_fac-A_C PF08646.10 KXS19839.1 - 2.7 7.7 5.5 4.1 7.1 5.5 1.1 1 0 0 1 1 1 0 Replication factor-A C terminal domain RRM_1 PF00076.22 KXS19840.1 - 1.6e-60 200.9 2.9 2.2e-16 59.4 0.0 6.8 7 0 0 7 7 7 6 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 KXS19840.1 - 0.0028 17.9 0.5 2.1 8.6 0.0 4.6 5 0 0 5 5 5 1 Cytosolic domain of 10TM putative phosphate transporter RRM_7 PF16367.5 KXS19840.1 - 0.0072 16.4 0.0 19 5.5 0.0 4.1 4 0 0 4 4 4 1 RNA recognition motif Limkain-b1 PF11608.8 KXS19840.1 - 0.055 13.5 1.9 8.5 6.5 0.1 4.7 5 1 0 5 5 5 0 Limkain b1 SET_assoc PF11767.8 KXS19840.1 - 0.22 11.2 0.7 8.9 6.0 0.0 3.1 3 0 0 3 3 3 0 Histone lysine methyltransferase SET associated ABC2_membrane PF01061.24 KXS19841.1 - 2.9e-64 216.4 46.6 9.2e-37 126.5 15.6 2.6 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 KXS19841.1 - 3.1e-28 99.0 0.0 1.2e-16 61.4 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KXS19841.1 - 2.2e-14 53.1 6.5 1.6e-12 47.1 0.0 4.4 4 0 0 4 4 4 1 CDR ABC transporter AAA_21 PF13304.6 KXS19841.1 - 0.0031 17.4 0.0 0.017 14.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KXS19841.1 - 0.045 14.1 0.1 0.44 10.9 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 KXS19841.1 - 0.086 13.1 0.1 0.53 10.6 0.1 2.3 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KXS19841.1 - 0.089 12.7 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_18 PF13238.6 KXS19841.1 - 0.2 12.2 0.0 2.3 8.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain SNF2_N PF00176.23 KXS19842.1 - 1.7e-73 247.4 0.0 2.2e-73 247.0 0.0 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.11 KXS19842.1 - 2.4e-20 72.3 0.0 4.7e-20 71.3 0.0 1.5 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.31 KXS19842.1 - 2.6e-13 50.3 0.0 5e-13 49.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.6 KXS19842.1 - 5.8e-10 38.8 9.3 1.7e-09 37.3 9.3 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KXS19842.1 - 3.1e-09 36.5 6.2 3.1e-09 36.5 6.2 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXS19842.1 - 7.7e-09 35.7 8.1 7.7e-09 35.7 8.1 2.1 2 0 0 2 2 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KXS19842.1 - 1.1e-07 31.8 6.9 3.3e-07 30.2 6.9 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KXS19842.1 - 1.5e-07 31.1 8.6 3.6e-07 29.9 8.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXS19842.1 - 1.4e-06 28.1 7.6 1.4e-06 28.1 7.6 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KXS19842.1 - 1.9e-06 27.9 9.5 4.3e-06 26.8 9.5 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 KXS19842.1 - 7.5e-06 26.1 3.1 7.5e-06 26.1 3.1 2.4 2 0 0 2 2 2 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 KXS19842.1 - 1.1e-05 25.2 5.7 1.1e-05 25.2 5.7 2.1 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KXS19842.1 - 0.0021 18.1 1.5 0.0021 18.1 1.5 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Rad50_zn_hook PF04423.14 KXS19842.1 - 0.0024 17.7 0.2 1.4 8.8 0.0 2.6 2 0 0 2 2 2 1 Rad50 zinc hook motif zf-Nse PF11789.8 KXS19842.1 - 0.0082 15.9 4.7 0.02 14.7 4.7 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_10 PF16685.5 KXS19842.1 - 0.034 14.3 5.8 0.09 12.9 5.8 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-CCHC_2 PF13696.6 KXS19842.1 - 0.049 13.5 2.8 0.069 13.0 1.6 1.9 2 0 0 2 2 2 0 Zinc knuckle zf-RING_6 PF14835.6 KXS19842.1 - 0.062 13.2 5.1 0.16 11.9 5.1 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zinc-ribbons_6 PF07191.12 KXS19842.1 - 3.1 7.8 7.7 2.8 8.0 4.1 2.3 2 0 0 2 2 2 0 zinc-ribbons Ank_4 PF13637.6 KXS19843.1 - 2.5e-13 50.2 0.0 1.2e-08 35.3 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXS19843.1 - 1.8e-11 44.0 0.2 4e-07 30.2 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXS19843.1 - 1e-09 38.8 0.0 4e-07 30.5 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXS19843.1 - 1.9e-08 33.9 1.2 0.0033 17.8 0.0 4.0 4 1 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 KXS19843.1 - 2.3e-07 30.9 0.2 0.07 13.6 0.0 3.6 4 0 0 4 4 4 2 Ankyrin repeat PEGA PF08308.11 KXS19843.1 - 0.056 13.3 0.0 13 5.7 0.0 2.2 2 0 0 2 2 2 0 PEGA domain Diphthami_syn_2 PF01902.17 KXS19845.1 - 8.9e-19 67.9 0.0 7.8e-18 64.8 0.0 1.9 2 0 0 2 2 2 1 Diphthamide synthase CutC PF03932.14 KXS19846.1 - 7.1e-62 208.5 0.1 8.9e-62 208.2 0.1 1.1 1 0 0 1 1 1 1 CutC family Abhydrolase_3 PF07859.13 KXS19847.1 - 3e-42 144.9 0.0 4.2e-42 144.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KXS19847.1 - 1.3e-07 30.8 0.0 8.2e-07 28.2 0.0 2.1 2 1 0 2 2 2 1 Steryl acetyl hydrolase Abhydrolase_2 PF02230.16 KXS19847.1 - 0.02 14.7 0.0 0.037 13.8 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase p450 PF00067.22 KXS19848.1 - 3.3e-14 52.5 0.0 5.3e-13 48.5 0.0 2.3 2 1 0 2 2 2 2 Cytochrome P450 NPR2 PF06218.11 KXS19849.1 - 1.8e-83 280.7 0.0 3.3e-64 217.3 0.0 3.0 1 1 1 2 2 2 2 Nitrogen permease regulator 2 HMG_box PF00505.19 KXS19850.1 - 4e-23 81.6 1.7 4.4e-23 81.5 1.7 1.0 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KXS19850.1 - 1.3e-17 64.1 1.6 1.5e-17 64.0 1.6 1.0 1 0 0 1 1 1 1 HMG-box domain CHDNT PF08073.12 KXS19850.1 - 7.5e-05 22.6 0.0 0.00012 21.9 0.0 1.3 1 0 0 1 1 1 1 CHDNT (NUC034) domain WD40 PF00400.32 KXS19851.1 - 2.1e-21 75.8 6.1 0.0038 18.0 0.1 9.8 10 0 0 10 10 10 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXS19851.1 - 1.8e-05 24.9 0.0 0.77 10.1 0.0 5.1 5 1 1 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 KXS19851.1 - 1.7 9.3 8.1 18 6.0 0.0 5.0 7 0 0 7 7 7 0 PQQ-like domain Ribosomal_L5_C PF00673.21 KXS19852.1 - 3.6e-16 59.1 0.0 6.3e-16 58.3 0.0 1.4 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 KXS19852.1 - 0.0019 18.5 0.0 0.0037 17.6 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L5 DAGAT PF03982.13 KXS19853.1 - 4.9e-69 232.5 0.0 4.9e-43 147.2 0.0 2.1 2 0 0 2 2 2 2 Diacylglycerol acyltransferase Caveolin PF01146.17 KXS19853.1 - 0.07 13.1 0.5 0.12 12.3 0.5 1.3 1 0 0 1 1 1 0 Caveolin SH3_9 PF14604.6 KXS19854.1 - 1.1e-07 31.6 0.1 1.9e-07 30.9 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXS19854.1 - 1.5e-05 24.5 0.0 3e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 SH3 domain Ank_3 PF13606.6 KXS19854.1 - 0.021 15.3 0.1 0.12 13.1 0.1 2.2 2 0 0 2 2 2 0 Ankyrin repeat Ank PF00023.30 KXS19854.1 - 0.06 13.8 0.1 0.74 10.4 0.1 2.4 2 0 0 2 2 2 0 Ankyrin repeat SH3_2 PF07653.17 KXS19854.1 - 0.12 12.1 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Variant SH3 domain Ank_5 PF13857.6 KXS19854.1 - 0.16 12.4 0.0 0.49 10.8 0.0 1.8 1 0 0 1 1 1 0 Ankyrin repeats (many copies) SH3_9 PF14604.6 KXS19855.1 - 3.3e-06 26.8 0.0 6.7e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Ank_3 PF13606.6 KXS19855.1 - 1.8e-05 24.8 0.0 0.0062 17.0 0.0 3.7 4 0 0 4 4 4 1 Ankyrin repeat SH3_1 PF00018.28 KXS19855.1 - 0.0004 19.9 0.0 0.00082 18.9 0.0 1.5 1 0 0 1 1 1 1 SH3 domain Ank_2 PF12796.7 KXS19855.1 - 0.0016 19.0 0.0 0.035 14.7 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXS19855.1 - 0.0085 16.7 0.0 4.7 7.9 0.0 3.5 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 KXS19855.1 - 0.021 15.2 0.1 7.8 7.1 0.0 2.8 3 0 0 3 3 3 0 Ankyrin repeat Ank_5 PF13857.6 KXS19855.1 - 0.031 14.6 0.0 0.45 10.9 0.0 2.7 3 0 0 3 3 3 0 Ankyrin repeats (many copies) ATG16 PF08614.11 KXS19855.1 - 0.042 14.1 3.4 0.069 13.4 3.4 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) SH3_9 PF14604.6 KXS19856.1 - 5.1e-06 26.3 0.0 8.9e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Ank_3 PF13606.6 KXS19856.1 - 5.9e-06 26.2 0.0 0.07 13.7 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 KXS19856.1 - 0.00076 20.0 0.0 0.74 10.5 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXS19856.1 - 0.012 16.1 0.0 1.5 9.5 0.0 3.1 2 1 0 2 2 2 0 Ankyrin repeats (3 copies) SH3_1 PF00018.28 KXS19856.1 - 0.014 15.0 0.0 0.025 14.2 0.0 1.4 1 0 0 1 1 1 0 SH3 domain SYS1 PF09801.9 KXS19859.1 - 1.2e-37 129.3 7.8 1.4e-37 129.1 7.8 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network MotB_plug PF13677.6 KXS19859.1 - 0.06 12.9 0.1 0.14 11.8 0.1 1.5 1 0 0 1 1 1 0 Membrane MotB of proton-channel complex MotA/MotB Proteasome PF00227.26 KXS19860.1 - 1.1e-58 197.9 0.1 1.6e-58 197.4 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KXS19860.1 - 3.6e-11 42.5 0.0 1.1e-10 40.9 0.0 1.9 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Mito_carr PF00153.27 KXS19860.1 - 0.17 11.8 0.0 7.5 6.5 0.0 2.4 2 0 0 2 2 2 0 Mitochondrial carrier protein Mito_carr PF00153.27 KXS19861.1 - 6.2e-20 70.9 0.0 4.6e-09 36.1 0.0 4.1 4 0 0 4 4 4 4 Mitochondrial carrier protein Cpn60_TCP1 PF00118.24 KXS19862.1 - 4.5e-152 507.1 15.6 5.2e-152 506.9 15.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Sua5_yciO_yrdC PF01300.18 KXS19862.1 - 0.035 13.6 0.0 0.1 12.1 0.0 1.8 2 0 0 2 2 2 0 Telomere recombination Peptidase_S8 PF00082.22 KXS19863.1 - 1.7e-33 116.2 0.5 3.4e-33 115.2 0.5 1.5 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 KXS19863.1 - 1.4e-24 85.9 0.8 3.4e-24 84.7 0.5 1.9 2 0 0 2 2 2 1 Proprotein convertase P-domain S8_pro-domain PF16470.5 KXS19863.1 - 1.7e-11 44.7 1.4 2e-11 44.5 0.1 1.8 2 0 0 2 2 2 1 Peptidase S8 pro-domain PQQ_3 PF13570.6 KXS19864.1 - 0.12 12.9 0.1 11 6.7 0.0 3.8 3 0 0 3 3 3 0 PQQ-like domain WD40 PF00400.32 KXS19864.1 - 0.71 10.9 2.7 26 5.9 0.0 3.9 4 0 0 4 4 4 0 WD domain, G-beta repeat LUC7 PF03194.15 KXS19865.1 - 1.7e-60 204.8 0.0 2e-60 204.6 0.0 1.0 1 0 0 1 1 1 1 LUC7 N_terminus FXMRP1_C_core PF12235.8 KXS19865.1 - 0.008 16.8 0.0 0.008 16.8 0.0 3.1 2 1 0 2 2 2 1 Fragile X-related 1 protein core C terminal zf_C2H2_13 PF18508.1 KXS19865.1 - 0.05 13.2 0.0 0.098 12.3 0.0 1.4 1 0 0 1 1 1 0 Zinc finger domain Mut7-C PF01927.16 KXS19865.1 - 0.058 13.5 0.3 0.11 12.6 0.3 1.4 1 0 0 1 1 1 0 Mut7-C RNAse domain USP7_ICP0_bdg PF12436.8 KXS19866.1 - 3.2e-62 210.0 0.3 1.2e-61 208.1 0.1 2.1 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.6 KXS19866.1 - 8.6e-56 188.9 0.1 1.1e-51 175.5 0.0 3.9 4 1 0 4 4 4 2 Ubiquitin-specific protease C-terminal UCH PF00443.29 KXS19866.1 - 1.1e-46 159.4 0.2 3.4e-46 157.8 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KXS19866.1 - 3.6e-22 79.4 0.0 1.1e-21 77.7 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.26 KXS19866.1 - 6.2e-09 36.0 0.0 1.6e-08 34.7 0.0 1.7 1 0 0 1 1 1 1 MATH domain ubiquitin PF00240.23 KXS19866.1 - 0.00044 19.9 0.1 0.035 13.9 0.0 3.6 3 0 0 3 3 3 1 Ubiquitin family Ubiquitin_2 PF14560.6 KXS19866.1 - 0.011 16.1 0.0 0.029 14.8 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin-like domain Acatn PF13000.7 KXS19867.1 - 2.2e-131 439.1 25.0 1.4e-71 241.7 12.7 3.4 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 RRM_1 PF00076.22 KXS19868.1 - 3.2e-12 46.1 0.1 4.9e-12 45.5 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.23 KXS19868.1 - 1.4e-08 34.4 1.2 2.8e-08 33.4 1.2 1.5 1 0 0 1 1 1 1 Zinc knuckle RRM_5 PF13893.6 KXS19868.1 - 0.00043 19.9 0.0 0.00066 19.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC_5 PF14787.6 KXS19868.1 - 0.0028 17.3 0.8 0.007 16.1 0.8 1.6 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger ProRS-C_1 PF09180.11 KXS19868.1 - 0.0071 16.5 0.0 0.013 15.7 0.0 1.4 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal zf-CCHC_2 PF13696.6 KXS19868.1 - 0.0097 15.7 1.4 0.019 14.8 1.4 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 KXS19868.1 - 0.022 14.7 0.1 0.043 13.8 0.1 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.6 KXS19868.1 - 0.031 14.0 0.2 0.063 13.0 0.2 1.5 1 0 0 1 1 1 0 Zinc knuckle PLU-1 PF08429.11 KXS19869.1 - 2.1e-46 158.7 3.5 6.9e-41 140.5 3.3 3.2 3 0 0 3 3 3 3 PLU-1-like protein PHD PF00628.29 KXS19869.1 - 3.7e-29 100.4 44.2 4.4e-12 45.7 3.2 4.3 4 0 0 4 4 4 3 PHD-finger ARID PF01388.21 KXS19869.1 - 6.9e-16 58.7 0.0 1.5e-15 57.6 0.0 1.6 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain JmjC PF02373.22 KXS19869.1 - 1.7e-13 51.0 0.0 3.7e-13 49.9 0.0 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase JmjN PF02375.17 KXS19869.1 - 0.0028 17.6 0.0 0.0082 16.1 0.0 1.9 1 0 0 1 1 1 1 jmjN domain Mt_ATP-synt_D PF05873.12 KXS19870.1 - 1.1e-14 54.5 0.0 1.5e-14 54.1 0.0 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) Vac_ImportDeg PF09783.9 KXS19871.1 - 7.5e-46 155.9 2.6 9.7e-46 155.5 2.6 1.0 1 0 0 1 1 1 1 Vacuolar import and degradation protein BRCT_3 PF18428.1 KXS19872.1 - 7.6e-11 42.0 0.0 9.5e-09 35.3 0.0 2.5 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KXS19872.1 - 6.9e-09 36.0 0.0 4e-05 23.9 0.0 2.3 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 KXS19872.1 - 1.4e-07 31.7 0.0 4.6e-07 30.1 0.0 1.9 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 KXS19872.1 - 3.6e-07 30.0 0.0 0.0001 22.1 0.0 2.3 2 0 0 2 2 2 2 Regulator of Ty1 transposition protein 107 BRCT domain GATA PF00320.27 KXS19873.1 - 1.6e-10 40.4 4.6 2.9e-10 39.6 4.6 1.5 1 0 0 1 1 1 1 GATA zinc finger Zn-ribbon_8 PF09723.10 KXS19873.1 - 0.034 14.3 0.2 0.07 13.3 0.2 1.5 1 0 0 1 1 1 0 Zinc ribbon domain DZR PF12773.7 KXS19873.1 - 0.037 14.1 0.7 0.072 13.1 0.7 1.4 1 0 0 1 1 1 0 Double zinc ribbon p450 PF00067.22 KXS19874.1 - 3.6e-07 29.3 0.1 0.68 8.6 0.1 3.9 4 0 0 4 4 4 4 Cytochrome P450 CLTH PF10607.9 KXS19875.1 - 6.1e-09 35.9 0.0 8.8e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SH3_9 PF14604.6 KXS19876.1 - 6.8e-08 32.3 0.1 2.1e-07 30.7 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 KXS19876.1 - 5.1e-06 26.0 0.0 1e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 SH3 domain Scs3p PF10261.9 KXS19877.1 - 2.5e-39 135.2 0.2 4.8e-39 134.3 0.2 1.4 1 1 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM Cwf_Cwc_15 PF04889.12 KXS19878.1 - 7.7 6.2 17.6 10 5.8 17.6 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein GTP_EFTU PF00009.27 KXS19879.1 - 8.2e-57 191.9 0.0 1.2e-56 191.3 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KXS19879.1 - 1.2e-29 102.9 0.0 2.5e-29 101.8 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KXS19879.1 - 2.4e-15 56.6 1.2 5.2e-15 55.6 1.2 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KXS19879.1 - 0.00021 21.4 0.0 0.00039 20.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase ER_lumen_recept PF00810.18 KXS19880.1 - 1.1e-52 178.8 12.9 1.4e-52 178.4 12.9 1.2 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.14 KXS19880.1 - 0.00099 18.8 8.2 0.039 13.7 0.9 2.9 3 0 0 3 3 3 2 PQ loop repeat COX7B PF05392.11 KXS19880.1 - 0.051 13.3 0.1 0.051 13.3 0.1 1.9 2 1 0 2 2 2 0 Cytochrome C oxidase chain VIIB Ank_2 PF12796.7 KXS19881.1 - 1.3e-16 60.9 0.0 0.00024 21.6 0.0 4.4 3 1 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXS19881.1 - 5.4e-16 58.7 0.3 0.12 13.0 0.0 6.6 5 1 1 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXS19881.1 - 5.8e-14 52.0 2.1 4.6e-06 26.8 0.1 4.7 4 1 0 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXS19881.1 - 1.1e-11 43.9 0.2 0.035 14.7 0.0 6.8 8 0 0 8 8 8 2 Ankyrin repeat Ank PF00023.30 KXS19881.1 - 1.6e-10 40.9 1.7 0.0018 18.7 0.0 4.6 4 1 0 4 4 4 2 Ankyrin repeat PX PF00787.24 KXS19881.1 - 2.5e-08 33.9 0.0 6.2e-08 32.6 0.0 1.7 1 1 0 1 1 1 1 PX domain VPS9 PF02204.18 KXS19881.1 - 0.026 14.7 0.0 0.13 12.5 0.0 2.1 2 0 0 2 2 2 0 Vacuolar sorting protein 9 (VPS9) domain DUF1843 PF08898.10 KXS19881.1 - 0.11 13.1 0.1 38 4.9 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1843) Rrp44_CSD1 PF17216.3 KXS19883.1 - 0.62 9.8 0.0 0.62 9.8 0.0 2.1 3 0 0 3 3 3 0 Rrp44-like cold shock domain Ist1 PF03398.14 KXS19885.1 - 0.00018 21.5 3.7 0.00028 20.9 3.7 1.3 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway AntA PF08346.12 KXS19885.1 - 0.13 12.9 0.0 0.36 11.4 0.0 1.7 1 0 0 1 1 1 0 AntA/AntB antirepressor Scramblase PF03803.15 KXS19886.1 - 2.4e-13 49.9 0.0 2.7e-13 49.7 0.0 1.0 1 0 0 1 1 1 1 Scramblase Metallophos PF00149.28 KXS19887.1 - 2.8e-29 103.1 0.1 4.4e-29 102.4 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.12 KXS19887.1 - 5.2e-22 77.9 0.0 9.1e-22 77.2 0.0 1.4 1 0 0 1 1 1 1 PPP5 TPR repeat region TPR_11 PF13414.6 KXS19887.1 - 0.00018 21.1 0.0 0.00077 19.1 0.0 2.0 2 0 0 2 2 2 1 TPR repeat TPR_1 PF00515.28 KXS19887.1 - 0.017 15.0 0.0 0.072 12.9 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 KXS19887.1 - 0.02 15.4 0.1 0.039 14.5 0.1 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 KXS19887.1 - 0.055 14.3 0.3 8.7 7.5 0.0 3.7 3 1 2 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 KXS19887.1 - 0.087 13.0 0.0 0.54 10.5 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 KXS19887.1 - 0.15 12.4 0.0 0.55 10.6 0.0 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat Phage_int_SAM_5 PF13102.6 KXS19887.1 - 0.22 11.9 0.0 0.43 11.0 0.0 1.4 1 0 0 1 1 1 0 Phage integrase SAM-like domain DUF4821 PF16092.5 KXS19888.1 - 5.5e-17 62.3 0.0 9.3e-17 61.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4821) Pyr_redox_2 PF07992.14 KXS19888.1 - 8.1e-07 28.6 0.0 1.6e-06 27.5 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase zf-B_box PF00643.24 KXS19890.1 - 2.8e-16 59.4 14.0 8.9e-09 35.4 4.5 2.4 2 0 0 2 2 2 2 B-box zinc finger UxaC PF02614.14 KXS19890.1 - 0.036 12.9 0.1 0.05 12.5 0.1 1.1 1 0 0 1 1 1 0 Glucuronate isomerase Aminotran_3 PF00202.21 KXS19891.1 - 2.2e-115 385.6 0.0 2.6e-115 385.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 KXS19891.1 - 0.022 14.0 0.0 0.029 13.6 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II DBR1 PF05011.13 KXS19892.1 - 2.9e-38 131.4 0.0 4.6e-38 130.8 0.0 1.3 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.28 KXS19892.1 - 3.8e-08 34.1 0.0 6.2e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Chromo PF00385.24 KXS19893.1 - 8.3e-08 32.0 5.3 8.4e-08 32.0 1.8 2.3 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.19 KXS19893.1 - 0.0072 16.4 0.2 0.047 13.8 0.0 2.0 2 0 0 2 2 2 1 Chromo shadow domain Mtf2_C PF14061.6 KXS19893.1 - 0.043 14.0 0.0 0.09 13.0 0.0 1.6 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 ParA PF10609.9 KXS19894.1 - 1.3e-98 329.3 0.2 1.5e-98 329.2 0.2 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KXS19894.1 - 1.8e-16 60.4 0.0 4.5e-16 59.1 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 KXS19894.1 - 1.4e-10 41.4 0.1 7.1e-09 35.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain MipZ PF09140.11 KXS19894.1 - 1.4e-08 34.3 0.0 2.3e-08 33.7 0.0 1.4 1 1 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.15 KXS19894.1 - 9.1e-07 28.4 0.9 7.6e-05 22.0 0.3 2.8 2 1 1 3 3 3 1 Anion-transporting ATPase Fer4_NifH PF00142.18 KXS19894.1 - 9.6e-06 25.2 0.0 0.00075 19.0 0.1 2.3 2 1 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family VirC1 PF07015.11 KXS19894.1 - 0.00039 19.8 0.0 0.0048 16.2 0.0 2.1 2 0 0 2 2 2 1 VirC1 protein AAA_25 PF13481.6 KXS19894.1 - 0.0029 17.2 1.6 0.0056 16.3 1.6 1.6 1 1 0 1 1 1 1 AAA domain CBP_BcsQ PF06564.12 KXS19894.1 - 0.013 14.9 1.2 0.036 13.5 0.7 1.8 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsQ PhoH PF02562.16 KXS19894.1 - 0.042 13.3 0.7 1 8.8 0.4 2.1 2 0 0 2 2 2 0 PhoH-like protein MeaB PF03308.16 KXS19894.1 - 0.047 12.7 1.1 0.058 12.4 0.2 1.5 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB CLP1_P PF16575.5 KXS19894.1 - 0.069 12.9 0.1 0.16 11.7 0.0 1.6 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AD PF09793.9 KXS19894.1 - 0.1 12.8 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 Anticodon-binding domain SIKE PF05769.11 KXS19895.1 - 8.1e-18 65.0 11.3 1.1e-17 64.6 11.3 1.1 1 0 0 1 1 1 1 SIKE family GAF_3 PF13492.6 KXS19895.1 - 0.061 13.7 0.2 0.11 12.8 0.2 1.4 1 0 0 1 1 1 0 GAF domain Rootletin PF15035.6 KXS19895.1 - 0.17 11.9 14.9 0.47 10.4 14.7 2.0 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion DUF5340 PF17275.2 KXS19895.1 - 0.76 10.0 4.8 3 8.0 1.2 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5340) Med9 PF07544.13 KXS19895.1 - 0.88 9.7 10.6 0.81 9.8 2.9 3.2 3 1 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 ubiquitin PF00240.23 KXS19897.1 - 1.2e-25 89.1 0.2 1.3e-25 88.9 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KXS19897.1 - 1.5e-14 53.6 0.3 1.6e-14 53.4 0.3 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 KXS19897.1 - 0.00019 21.3 0.0 0.00022 21.1 0.0 1.1 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_2 PF14560.6 KXS19897.1 - 0.00072 20.0 0.1 0.00081 19.8 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_5 PF18037.1 KXS19897.1 - 0.018 15.4 0.1 0.021 15.2 0.1 1.1 1 0 0 1 1 1 0 Ubiquitin-like domain UN_NPL4 PF11543.8 KXS19897.1 - 0.053 14.0 0.2 0.1 13.1 0.2 1.4 1 1 0 1 1 1 0 Nuclear pore localisation protein NPL4 Rad60-SLD_2 PF13881.6 KXS19897.1 - 0.14 12.3 0.1 0.21 11.7 0.1 1.5 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Ubiq_cyt_C_chap PF03981.12 KXS19898.1 - 1.3e-31 109.6 0.3 3.7e-31 108.1 0.1 1.7 2 0 0 2 2 2 1 Ubiquinol-cytochrome C chaperone PI3Ka PF00613.20 KXS19899.1 - 2.5e-54 183.5 0.0 4e-54 182.8 0.0 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 KXS19899.1 - 1.2e-45 156.3 0.0 4e-30 105.4 0.0 2.4 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 KXS19899.1 - 1.8e-33 115.4 0.0 3.5e-33 114.5 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 NADH-u_ox-rdase PF10785.9 KXS19900.1 - 3.2e-13 50.2 1.2 5.7e-13 49.4 1.2 1.4 1 1 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit AAA_31 PF13614.6 KXS19901.1 - 1.4e-14 54.4 0.0 2.2e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 KXS19901.1 - 1.2e-12 48.0 0.1 2.3e-12 47.1 0.0 1.5 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 KXS19901.1 - 2.3e-07 30.5 0.2 4.3e-07 29.6 0.1 1.4 2 0 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase Fer4_NifH PF00142.18 KXS19901.1 - 4.9e-07 29.5 0.0 8.2e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family CBP_BcsQ PF06564.12 KXS19901.1 - 1.1e-06 28.3 0.1 1.4e-06 28.0 0.1 1.1 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsQ ArsA_ATPase PF02374.15 KXS19901.1 - 3.9e-06 26.3 0.2 5.1e-06 25.9 0.2 1.1 1 0 0 1 1 1 1 Anion-transporting ATPase MipZ PF09140.11 KXS19901.1 - 0.00014 21.3 0.3 0.00018 20.9 0.3 1.1 1 0 0 1 1 1 1 ATPase MipZ VirC1 PF07015.11 KXS19901.1 - 0.00075 18.9 0.0 0.00091 18.6 0.0 1.1 1 0 0 1 1 1 1 VirC1 protein SRP54 PF00448.22 KXS19901.1 - 0.003 17.2 0.1 0.0042 16.7 0.1 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain DUF1611 PF07755.11 KXS19901.1 - 0.051 12.8 0.4 0.074 12.3 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1611_C) P-loop domain MeaB PF03308.16 KXS19901.1 - 0.063 12.3 0.0 0.078 12.0 0.0 1.1 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Mur_ligase_M PF08245.12 KXS19901.1 - 0.15 12.1 0.0 0.2 11.7 0.0 1.2 1 0 0 1 1 1 0 Mur ligase middle domain ADK PF00406.22 KXS19902.1 - 2.5e-139 459.4 0.0 2.3e-45 154.4 0.0 3.1 3 0 0 3 3 3 3 Adenylate kinase AAA_17 PF13207.6 KXS19902.1 - 3.2e-101 335.2 0.5 7.4e-35 120.3 0.1 3.2 3 0 0 3 3 3 3 AAA domain AAA_18 PF13238.6 KXS19902.1 - 3.2e-27 95.6 0.0 4.9e-09 36.8 0.0 3.4 3 0 0 3 3 3 3 AAA domain AAA_33 PF13671.6 KXS19902.1 - 3.3e-22 79.2 0.0 3.2e-06 27.3 0.0 3.6 3 1 0 3 3 3 3 AAA domain Cytidylate_kin PF02224.18 KXS19902.1 - 4.6e-09 36.3 0.7 0.17 11.6 0.0 3.3 3 0 0 3 3 3 3 Cytidylate kinase Ploopntkinase3 PF18751.1 KXS19902.1 - 4.2e-08 33.3 0.1 0.039 13.9 0.0 3.3 3 0 0 3 3 3 2 P-loop Nucleotide Kinase3 Zeta_toxin PF06414.12 KXS19902.1 - 1.5e-07 30.9 0.2 0.13 11.6 0.0 3.5 3 0 0 3 3 3 2 Zeta toxin AAA_19 PF13245.6 KXS19902.1 - 2.6e-07 31.1 0.3 1.3 9.4 0.0 3.5 3 0 0 3 3 3 3 AAA domain Thymidylate_kin PF02223.17 KXS19902.1 - 1.3e-06 28.2 7.9 0.18 11.5 0.0 5.0 6 0 0 6 6 6 2 Thymidylate kinase AAA_22 PF13401.6 KXS19902.1 - 3e-06 27.5 0.4 0.64 10.3 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_28 PF13521.6 KXS19902.1 - 6.1e-05 23.3 1.6 0.36 11.1 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.6 KXS19902.1 - 7.5e-05 23.2 0.1 2.3 8.6 0.0 3.7 3 0 0 3 3 3 1 AAA ATPase domain SRP54 PF00448.22 KXS19902.1 - 0.00024 20.8 1.4 0.21 11.2 0.0 3.3 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain CPT PF07931.12 KXS19902.1 - 0.00039 20.3 0.1 0.058 13.2 0.0 3.1 3 0 0 3 3 3 1 Chloramphenicol phosphotransferase-like protein NTPase_1 PF03266.15 KXS19902.1 - 0.00075 19.4 1.1 1.4 8.8 0.0 3.3 3 0 0 3 3 3 1 NTPase NACHT PF05729.12 KXS19902.1 - 0.00092 19.2 1.5 6.7 6.6 0.0 3.9 4 0 0 4 4 4 0 NACHT domain T2SSE PF00437.20 KXS19902.1 - 0.003 16.6 0.0 1.1 8.3 0.0 3.0 3 0 0 3 3 3 1 Type II/IV secretion system protein PAS_7 PF12860.7 KXS19902.1 - 0.0045 17.1 0.0 1.3 9.2 0.0 3.4 3 0 0 3 3 3 1 PAS fold AAA_29 PF13555.6 KXS19902.1 - 0.005 16.6 0.6 5.2 6.9 0.0 3.3 3 0 0 3 3 3 1 P-loop containing region of AAA domain ATP_bind_1 PF03029.17 KXS19902.1 - 0.0055 16.5 5.6 4.9 6.9 0.1 3.4 3 0 0 3 3 3 1 Conserved hypothetical ATP binding protein AAA_30 PF13604.6 KXS19902.1 - 0.01 15.6 2.1 17 5.0 0.0 3.4 3 0 0 3 3 3 0 AAA domain dNK PF01712.19 KXS19902.1 - 0.017 15.0 0.6 47 3.7 0.0 4.1 4 0 0 4 4 4 0 Deoxynucleoside kinase Hydin_ADK PF17213.3 KXS19902.1 - 0.028 14.7 0.0 0.32 11.3 0.0 2.6 3 0 0 3 3 3 0 Hydin Adenylate kinase-like domain AAA_24 PF13479.6 KXS19902.1 - 0.036 13.8 0.5 29 4.3 0.0 3.2 3 0 0 3 3 3 0 AAA domain CoaE PF01121.20 KXS19902.1 - 0.047 13.4 3.8 1.4 8.5 0.0 3.7 4 0 0 4 4 4 0 Dephospho-CoA kinase ABC_tran PF00005.27 KXS19902.1 - 0.051 14.1 0.1 36 4.9 0.0 3.4 3 0 0 3 3 3 0 ABC transporter AAA PF00004.29 KXS19902.1 - 0.053 13.9 4.9 18 5.7 0.1 4.0 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 KXS19902.1 - 0.061 12.7 0.4 8.5 5.7 0.0 3.0 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI DUF2075 PF09848.9 KXS19902.1 - 0.084 12.1 3.2 5.2 6.2 0.1 3.0 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) ATPase PF06745.13 KXS19902.1 - 0.11 11.8 0.1 47 3.2 0.0 3.3 3 0 0 3 3 3 0 KaiC MeaB PF03308.16 KXS19902.1 - 0.11 11.5 0.1 22 3.9 0.0 3.0 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB KTI12 PF08433.10 KXS19902.1 - 0.12 11.8 0.3 32 3.8 0.0 3.1 3 0 0 3 3 3 0 Chromatin associated protein KTI12 Viral_helicase1 PF01443.18 KXS19902.1 - 0.12 12.1 2.6 32 4.2 0.1 3.2 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase FtsK_SpoIIIE PF01580.18 KXS19902.1 - 0.19 11.0 0.1 33 3.7 0.0 3.0 3 0 0 3 3 3 0 FtsK/SpoIIIE family Voldacs PF03517.13 KXS19903.1 - 6.9e-15 55.4 0.0 3.9e-14 52.9 0.0 2.1 1 1 0 1 1 1 1 Regulator of volume decrease after cellular swelling PhoLip_ATPase_C PF16212.5 KXS19904.1 - 2.3e-71 240.5 24.8 2.3e-71 240.5 24.8 2.9 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KXS19904.1 - 2.8e-22 78.2 1.5 3.9e-22 77.7 0.0 2.0 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 KXS19904.1 - 1.3e-11 44.4 0.0 8.8e-11 41.7 0.0 2.1 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KXS19904.1 - 1.3e-09 38.7 0.0 7.7e-05 23.1 0.0 2.9 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KXS19904.1 - 1.5e-05 24.6 4.9 0.0025 17.4 0.0 2.7 3 0 0 3 3 3 2 E1-E2 ATPase Hydrolase_3 PF08282.12 KXS19904.1 - 0.0019 18.0 0.2 0.013 15.3 0.1 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Nuc_sug_transp PF04142.15 KXS19905.1 - 6.1e-10 38.8 1.4 1.4e-09 37.6 1.4 1.6 1 1 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 KXS19905.1 - 4.1e-08 33.5 12.6 5.9e-05 23.3 1.2 2.7 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 KXS19905.1 - 4.2e-07 29.6 0.4 6.6e-05 22.4 0.0 2.2 2 0 0 2 2 2 2 Triose-phosphate Transporter family CRT-like PF08627.10 KXS19905.1 - 1.9e-05 23.8 1.4 0.00014 20.9 0.0 2.6 3 0 0 3 3 3 1 CRT-like, chloroquine-resistance transporter-like PUNUT PF16913.5 KXS19905.1 - 0.00089 18.6 0.0 0.0015 17.9 0.0 1.3 1 0 0 1 1 1 1 Purine nucleobase transmembrane transport UAA PF08449.11 KXS19905.1 - 0.014 14.6 5.2 0.047 12.9 5.2 1.9 1 1 0 1 1 1 0 UAA transporter family TatD_DNase PF01026.21 KXS19906.1 - 2e-47 161.7 0.0 2.4e-47 161.5 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase baeRF_family10 PF18854.1 KXS19906.1 - 0.16 12.2 0.0 0.3 11.3 0.0 1.4 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 10 CENP-C_C PF11699.8 KXS19907.1 - 4.5e-24 84.5 0.0 7.3e-24 83.8 0.0 1.4 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_2 PF07883.11 KXS19907.1 - 1.4e-07 31.2 0.0 2.9e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 Cupin domain DUF812 PF05667.11 KXS19908.1 - 0.0034 16.3 18.3 0.0034 16.3 18.3 4.6 2 2 2 4 4 4 3 Protein of unknown function (DUF812) TPR_MLP1_2 PF07926.12 KXS19908.1 - 0.011 15.8 15.5 0.011 15.8 15.5 8.1 2 1 5 7 7 7 0 TPR/MLP1/MLP2-like protein ABC_tran PF00005.27 KXS19909.1 - 1.1e-21 77.8 0.0 3.6e-21 76.1 0.0 1.8 2 0 0 2 2 2 1 ABC transporter ABC2_membrane PF01061.24 KXS19909.1 - 4.8e-20 71.9 16.8 4.8e-20 71.9 16.8 1.8 2 0 0 2 2 2 1 ABC-2 type transporter AAA_21 PF13304.6 KXS19909.1 - 4.2e-05 23.5 0.1 0.12 12.2 0.1 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KXS19909.1 - 0.00078 19.9 0.1 0.0015 18.9 0.1 1.5 1 0 0 1 1 1 1 AAA ATPase domain Phageshock_PspG PF09583.10 KXS19909.1 - 0.011 16.0 0.8 0.04 14.2 0.8 2.0 1 0 0 1 1 1 0 Phage shock protein G (Phageshock_PspG) ABC2_membrane_3 PF12698.7 KXS19909.1 - 0.097 11.8 14.6 0.037 13.1 12.2 1.5 1 1 0 1 1 1 0 ABC-2 family transporter protein AAA_29 PF13555.6 KXS19909.1 - 0.1 12.3 0.3 0.25 11.1 0.3 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.6 KXS19909.1 - 0.19 11.3 1.5 0.48 10.0 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 KXS19909.1 - 0.2 12.0 0.2 0.42 10.9 0.2 1.4 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 KXS19909.1 - 0.21 10.6 0.0 0.4 9.7 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein NACHT PF05729.12 KXS19909.1 - 0.21 11.5 0.2 0.37 10.7 0.2 1.4 1 0 0 1 1 1 0 NACHT domain RsgA_GTPase PF03193.16 KXS19909.1 - 0.23 11.3 0.2 0.49 10.3 0.2 1.4 1 0 0 1 1 1 0 RsgA GTPase Pox_A32 PF04665.12 KXS19909.1 - 0.26 10.7 0.1 0.43 10.0 0.1 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein Sulfotransfer_3 PF13469.6 KXS19910.1 - 0.011 16.2 0.1 0.83 10.0 0.0 2.7 3 1 0 3 3 3 0 Sulfotransferase family Peptidase_M28 PF04389.17 KXS19911.1 - 2e-33 115.8 0.0 3.9e-33 114.8 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M28 Ank_2 PF12796.7 KXS19912.1 - 2.5e-24 85.7 2.9 2.4e-12 47.3 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXS19912.1 - 4.9e-17 61.8 5.6 1.1e-10 41.5 0.4 4.1 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXS19912.1 - 1.3e-15 57.5 4.1 1.1e-06 29.1 0.1 3.9 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 KXS19912.1 - 5.9e-09 36.0 4.8 0.0075 16.7 0.0 4.5 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 KXS19912.1 - 3.1e-06 27.1 6.1 0.0029 17.9 0.0 5.1 5 0 0 5 5 5 1 Ankyrin repeat Rootletin PF15035.6 KXS19912.1 - 6.4 6.8 9.1 4.5 7.3 0.5 2.8 2 1 0 3 3 3 0 Ciliary rootlet component, centrosome cohesion Acyl-CoA_dh_M PF02770.19 KXS19913.1 - 3.4e-18 65.6 0.0 8.2e-18 64.4 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KXS19913.1 - 7.5e-14 52.4 0.1 1.6e-13 51.3 0.0 1.6 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain PTN_MK_N PF05196.13 KXS19914.1 - 0.031 14.5 0.8 0.065 13.5 0.8 1.5 1 0 0 1 1 1 0 PTN/MK heparin-binding protein family, N-terminal domain PRIMA1 PF16101.5 KXS19914.1 - 0.45 10.6 6.9 1.8 8.6 4.2 2.3 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 PTN_MK_N PF05196.13 KXS19916.1 - 0.029 14.6 0.8 0.061 13.6 0.8 1.5 1 0 0 1 1 1 0 PTN/MK heparin-binding protein family, N-terminal domain PRIMA1 PF16101.5 KXS19916.1 - 0.39 10.8 6.9 1.7 8.7 4.2 2.4 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Acyl-CoA_dh_1 PF00441.24 KXS19917.1 - 3.3e-28 98.8 0.2 4.1e-28 98.5 0.2 1.1 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.11 KXS19917.1 - 7.3e-10 39.2 0.2 1.1e-09 38.7 0.2 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KXS19917.1 - 0.0014 18.8 0.0 0.0027 17.9 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain CSN8_PSD8_EIF3K PF10075.9 KXS19918.1 - 6.4e-14 52.1 0.0 2.6e-12 46.9 0.0 2.2 1 1 0 1 1 1 1 CSN8/PSMD8/EIF3K family Pre-PUA PF17832.1 KXS19919.1 - 2.3e-20 73.1 0.0 1e-19 71.0 0.0 2.1 2 0 0 2 2 2 1 Pre-PUA-like domain SUI1 PF01253.22 KXS19919.1 - 6.7e-20 71.4 0.0 2e-19 69.9 0.0 1.9 2 0 0 2 2 2 1 Translation initiation factor SUI1 PUA PF01472.20 KXS19919.1 - 0.0016 18.4 0.0 0.0052 16.7 0.0 1.8 1 0 0 1 1 1 1 PUA domain Kin17_mid PF10357.9 KXS19919.1 - 0.0022 17.9 0.0 0.034 14.0 0.0 2.2 2 0 0 2 2 2 1 Domain of Kin17 curved DNA-binding protein SWIB PF02201.18 KXS19919.1 - 0.0047 16.8 0.1 0.011 15.6 0.1 1.5 1 0 0 1 1 1 1 SWIB/MDM2 domain Pkinase_Tyr PF07714.17 KXS19920.1 - 3.3e-66 223.2 0.0 9.8e-66 221.7 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 KXS19920.1 - 1.8e-55 188.1 0.0 1.8e-54 184.9 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Kdo PF06293.14 KXS19920.1 - 0.084 12.2 0.8 0.29 10.5 0.1 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DEAD PF00270.29 KXS19921.1 - 4.9e-49 166.5 0.0 1.8e-48 164.6 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXS19921.1 - 3.4e-26 91.8 0.0 7.9e-26 90.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXS19921.1 - 0.11 12.5 0.0 0.66 10.0 0.0 2.3 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit SecA_DEAD PF07517.14 KXS19921.1 - 0.12 11.7 0.0 0.25 10.6 0.0 1.5 1 0 0 1 1 1 0 SecA DEAD-like domain Costars PF14705.6 KXS19922.1 - 1e-28 99.3 0.9 1.1e-28 99.2 0.9 1.0 1 0 0 1 1 1 1 Costars Glyoxal_oxid_N PF07250.11 KXS19923.1 - 8.5e-39 133.2 0.0 7e-36 123.6 0.0 3.7 3 2 1 4 4 4 2 Glyoxal oxidase N-terminus Kelch_2 PF07646.15 KXS19923.1 - 0.00014 21.7 0.1 1.9 8.6 0.0 4.9 5 0 0 5 5 5 1 Kelch motif Chitin_bind_1 PF00187.19 KXS19923.1 - 0.13 12.8 19.4 0.31 11.5 19.4 1.7 1 0 0 1 1 1 0 Chitin recognition protein Glyoxal_oxid_N PF07250.11 KXS19925.1 - 7e-38 130.2 0.0 6.8e-37 126.9 0.0 2.4 2 1 0 2 2 2 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 KXS19925.1 - 1.9e-23 82.6 0.9 4.2e-23 81.4 0.9 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_2 PF07646.15 KXS19925.1 - 0.0013 18.6 0.4 1.9 8.6 0.0 3.8 3 1 1 4 4 4 2 Kelch motif Kelch_4 PF13418.6 KXS19925.1 - 0.029 14.4 0.1 42 4.2 0.0 4.0 3 0 0 3 3 3 0 Galactose oxidase, central domain GPI-anchored PF10342.9 KXS19925.1 - 0.055 14.2 0.1 0.21 12.3 0.1 2.0 1 0 0 1 1 1 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Chitin_bind_1 PF00187.19 KXS19925.1 - 0.55 10.7 22.2 1.4 9.5 22.2 1.7 1 1 0 1 1 1 0 Chitin recognition protein Glyco_hydro_63 PF03200.16 KXS19926.1 - 7.4e-08 31.6 4.1 0.0055 15.5 0.1 4.3 4 1 0 4 4 4 2 Glycosyl hydrolase family 63 C-terminal domain CDC50 PF03381.15 KXS19927.1 - 1.4e-94 316.8 0.7 1.7e-94 316.5 0.7 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family DUF5325 PF17259.2 KXS19927.1 - 2.7 7.9 5.1 4.7 7.2 0.3 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5325) Apolipoprotein PF01442.18 KXS19928.1 - 0.0036 17.2 4.6 0.0044 16.9 4.6 1.1 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Exonuc_VII_L PF02601.15 KXS19928.1 - 0.076 12.6 3.4 0.088 12.4 3.4 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF2564 PF10819.8 KXS19928.1 - 0.083 13.3 2.8 0.2 12.1 2.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2564) DUF883 PF05957.13 KXS19928.1 - 0.31 11.7 4.5 0.8 10.4 4.5 1.7 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) ADK PF00406.22 KXS19929.1 - 5.8e-58 195.3 0.0 8.8e-58 194.7 0.0 1.3 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KXS19929.1 - 3.1e-19 69.7 0.3 1.3e-18 67.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.14 KXS19929.1 - 4.5e-16 58.5 0.0 1.2e-15 57.2 0.0 1.7 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_18 PF13238.6 KXS19929.1 - 0.00025 21.6 0.0 0.00067 20.2 0.0 1.7 2 0 0 2 2 2 1 AAA domain ATPase PF06745.13 KXS19929.1 - 0.04 13.2 1.2 0.084 12.2 0.2 2.0 2 0 0 2 2 2 0 KaiC Hydin_ADK PF17213.3 KXS19929.1 - 1.4 9.1 5.3 23 5.2 0.0 3.1 2 1 1 3 3 3 0 Hydin Adenylate kinase-like domain DUF3987 PF13148.6 KXS19929.1 - 1.5 7.7 5.2 4 6.4 4.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3987) HAD PF12710.7 KXS19930.1 - 4.8e-19 69.5 0.1 6.6e-19 69.0 0.1 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KXS19930.1 - 0.00089 19.6 0.0 0.024 14.9 0.0 2.2 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.12 KXS19930.1 - 0.018 14.5 0.0 0.038 13.5 0.0 1.6 1 1 0 1 1 1 0 Pyrimidine 5'-nucleotidase (UMPH-1) GBP_repeat PF02526.14 KXS19930.1 - 0.13 12.0 0.1 0.25 11.1 0.1 1.4 1 0 0 1 1 1 0 Glycophorin-binding protein DLH PF01738.18 KXS19931.1 - 4.6e-18 65.6 0.0 5.7e-18 65.3 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 KXS19931.1 - 0.0042 16.8 0.0 0.0098 15.6 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase PF07224.11 KXS19931.1 - 0.013 14.5 0.0 0.017 14.2 0.0 1.1 1 0 0 1 1 1 0 Chlorophyllase TPT PF03151.16 KXS19932.1 - 3.5e-18 66.0 7.5 5.4e-18 65.3 7.5 1.3 1 1 0 1 1 1 1 Triose-phosphate Transporter family TMEM234 PF10639.9 KXS19932.1 - 0.019 15.0 4.3 2.5 8.2 0.4 2.6 2 0 0 2 2 2 0 Putative transmembrane family 234 EamA PF00892.20 KXS19932.1 - 0.31 11.2 18.2 0.23 11.6 3.6 2.6 3 0 0 3 3 3 0 EamA-like transporter family SH3_9 PF14604.6 KXS19933.1 - 1.7e-06 27.8 0.3 3.5e-06 26.8 0.0 1.7 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 KXS19933.1 - 1.1e-05 24.9 0.0 3.3e-05 23.4 0.0 1.8 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 KXS19933.1 - 0.12 12.1 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain Anillin_N PF16018.5 KXS19933.1 - 0.17 12.5 0.2 0.48 11.1 0.1 1.8 2 0 0 2 2 2 0 Anillin N-terminus Phage_holin_2_4 PF16082.5 KXS19933.1 - 0.2 11.4 2.7 0.45 10.3 2.7 1.5 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like Glyoxal_oxid_N PF07250.11 KXS19934.1 - 1.4e-38 132.5 0.0 1.3e-36 126.1 0.1 3.0 2 2 0 2 2 2 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 KXS19934.1 - 1.1e-22 80.1 0.1 2.6e-22 78.9 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_2 PF07646.15 KXS19934.1 - 0.00081 19.3 0.1 3.6 7.7 0.1 3.3 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.6 KXS19934.1 - 0.0055 16.7 0.1 5.8 7.0 0.0 3.1 3 0 0 3 3 3 2 Galactose oxidase, central domain Chitin_bind_1 PF00187.19 KXS19934.1 - 0.028 14.9 16.0 0.06 13.8 16.0 1.6 1 0 0 1 1 1 0 Chitin recognition protein Pkinase PF00069.25 KXS19935.1 - 1.9e-55 188.1 0.0 5.4e-48 163.6 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXS19935.1 - 7.2e-34 117.2 0.0 1.3e-31 109.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KXS19935.1 - 2e-09 37.2 0.0 2.6e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KXS19935.1 - 0.00011 22.2 0.0 0.35 10.7 0.1 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXS19935.1 - 0.0015 17.4 0.1 0.0028 16.5 0.0 1.3 1 1 0 1 1 1 1 Fungal protein kinase WD40 PF00400.32 KXS19936.1 - 1.6e-14 54.0 3.7 0.0042 17.9 0.0 5.7 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXS19936.1 - 0.00053 20.2 0.0 1 9.7 0.2 3.6 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Csm1_N PF18504.1 KXS19936.1 - 0.1 12.9 0.2 0.18 12.2 0.2 1.3 1 0 0 1 1 1 0 Csm1 N-terminal domain ZapB PF06005.12 KXS19936.1 - 0.1 13.0 0.8 0.17 12.4 0.8 1.2 1 0 0 1 1 1 0 Cell division protein ZapB HALZ PF02183.18 KXS19936.1 - 0.16 12.2 3.7 1 9.6 3.7 2.0 1 1 0 1 1 1 0 Homeobox associated leucine zipper bZIP_1 PF00170.21 KXS19936.1 - 0.26 11.4 2.2 0.45 10.6 2.2 1.3 1 0 0 1 1 1 0 bZIP transcription factor Gln-synt_C PF00120.24 KXS19937.1 - 1.8e-85 287.0 0.0 2.2e-85 286.7 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N_2 PF16952.5 KXS19937.1 - 0.092 12.6 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Glutamine synthetase N-terminal domain Methyltransf_31 PF13847.6 KXS19940.1 - 1.5e-11 44.4 0.0 2.2e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXS19940.1 - 4.5e-09 36.8 0.1 1.7e-08 35.0 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXS19940.1 - 1.2e-08 35.6 0.3 1.1e-07 32.5 0.1 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXS19940.1 - 0.0013 19.5 0.0 0.0042 17.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.6 KXS19940.1 - 0.0029 17.6 0.0 0.0045 17.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXS19940.1 - 0.046 13.3 0.0 0.077 12.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain PRIMA1 PF16101.5 KXS19940.1 - 0.11 12.5 0.5 0.21 11.6 0.5 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 adh_short_C2 PF13561.6 KXS19941.1 - 4.1e-41 141.1 0.0 5.7e-41 140.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXS19941.1 - 6.1e-38 130.2 0.0 9.7e-38 129.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXS19941.1 - 1.3e-06 28.5 0.0 2e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 KXS19941.1 - 0.019 14.3 0.0 0.038 13.3 0.0 1.5 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Aminotran_1_2 PF00155.21 KXS19942.1 - 6.1e-47 160.5 0.0 7.3e-47 160.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Guanylate_kin PF00625.21 KXS19943.1 - 3.4e-44 150.7 0.0 1.1e-40 139.3 0.0 2.4 2 0 0 2 2 2 2 Guanylate kinase LRR_4 PF12799.7 KXS19943.1 - 2.2e-19 69.2 23.8 6.9e-08 32.7 1.9 6.4 3 2 3 7 7 7 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXS19943.1 - 1.2e-16 60.2 19.8 2.9e-05 23.7 0.3 4.6 4 0 0 4 4 4 4 Leucine rich repeat LRR_9 PF14580.6 KXS19943.1 - 5.9e-12 45.4 0.1 7.9e-05 22.2 0.4 3.4 3 0 0 3 3 3 3 Leucine-rich repeat LRR_6 PF13516.6 KXS19943.1 - 8.7e-09 34.7 12.5 3 8.1 0.9 7.7 8 0 0 8 8 8 3 Leucine Rich repeat LRR_1 PF00560.33 KXS19943.1 - 6e-05 23.0 15.5 3.9 8.4 0.2 7.2 6 1 0 6 6 6 2 Leucine Rich Repeat AAA_18 PF13238.6 KXS19943.1 - 0.00082 19.9 0.0 0.0021 18.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KXS19943.1 - 0.0034 17.5 0.1 0.25 11.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KXS19943.1 - 0.046 14.1 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.14 KXS19943.1 - 0.068 13.2 0.0 0.18 11.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KXS19943.1 - 0.089 12.5 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain RsgA_GTPase PF03193.16 KXS19943.1 - 0.1 12.5 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase zf-C2H2 PF00096.26 KXS19944.1 - 1.4e-11 44.2 12.5 0.00012 22.3 0.9 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXS19944.1 - 1.2e-09 38.2 11.0 0.0071 17.1 0.5 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KXS19944.1 - 0.00036 20.8 15.7 0.032 14.6 0.2 4.5 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2_6 PF13912.6 KXS19944.1 - 0.00052 20.0 3.6 0.015 15.3 0.3 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger zf-met PF12874.7 KXS19944.1 - 0.018 15.4 3.4 0.34 11.3 0.2 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.6 KXS19944.1 - 0.098 12.6 11.9 3.5 7.6 0.1 3.6 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-C2H2_2 PF12756.7 KXS19944.1 - 0.15 12.4 1.0 0.83 10.0 0.1 2.2 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_3rep PF18868.1 KXS19944.1 - 0.18 12.5 5.8 0.64 10.7 0.9 2.8 1 1 2 3 3 3 0 Zinc finger C2H2-type, 3 repeats DUF1192 PF06698.11 KXS19944.1 - 0.19 11.8 0.1 0.48 10.5 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1192) zf-C2HE PF16278.5 KXS19944.1 - 0.19 12.2 4.1 0.69 10.4 0.1 2.8 2 1 1 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_jaz PF12171.8 KXS19944.1 - 0.26 11.6 2.4 13 6.2 0.1 2.7 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding C1_2 PF03107.16 KXS19944.1 - 1.2 9.6 3.4 70 3.9 3.4 2.5 1 1 0 1 1 1 0 C1 domain DUF2855 PF11017.8 KXS19945.1 - 1.9e-80 271.2 0.0 2.1e-80 271.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2855) Glyco_hydro_85 PF03644.13 KXS19945.1 - 0.093 12.1 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 85 Coat_F PF07875.12 KXS19946.1 - 4.8 7.5 8.4 0.93 9.8 1.7 3.1 1 1 1 2 2 2 0 Coat F domain DSPc PF00782.20 KXS19948.1 - 8.7e-15 54.7 0.0 1e-14 54.5 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KXS19948.1 - 4.2e-05 23.2 0.1 6.2e-05 22.7 0.1 1.3 1 1 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.13 KXS19948.1 - 0.00033 20.3 0.0 0.00049 19.7 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 KXS19948.1 - 0.0015 18.6 0.0 0.0028 17.8 0.0 1.4 1 1 0 1 1 1 1 Inositol hexakisphosphate Myotub-related PF06602.14 KXS19948.1 - 0.0039 16.2 0.0 0.0047 15.9 0.0 1.2 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Init_tRNA_PT PF04179.12 KXS19948.1 - 0.032 14.5 0.0 0.039 14.2 0.0 1.3 1 0 0 1 1 1 0 Rit1 DUSP-like domain FRB_dom PF08771.11 KXS19948.1 - 0.09 13.2 0.0 0.33 11.4 0.0 1.8 2 0 0 2 2 2 0 FKBP12-rapamycin binding domain Y_phosphatase3 PF13350.6 KXS19948.1 - 0.14 12.1 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family LRR_9 PF14580.6 KXS19949.1 - 1.5e-62 210.2 0.1 1.9e-62 209.8 0.1 1.1 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 KXS19949.1 - 3.7e-10 39.4 1.5 3.7e-10 39.4 1.5 2.2 2 0 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 KXS19949.1 - 7.4e-10 38.9 8.5 2.8e-06 27.5 0.8 3.3 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KXS19949.1 - 0.0033 17.3 2.2 22 5.4 0.2 4.7 5 0 0 5 5 5 1 Leucine Rich repeat RabGAP-TBC PF00566.18 KXS19950.1 - 8.1e-13 48.5 0.0 2.3e-08 34.0 0.0 2.2 2 0 0 2 2 2 2 Rab-GTPase-TBC domain RabGAP-TBC PF00566.18 KXS19951.1 - 3.1e-08 33.6 0.3 4.2e-08 33.1 0.3 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain YtpI PF14007.6 KXS19953.1 - 0.046 13.8 0.1 0.046 13.8 0.1 3.4 4 0 0 4 4 4 0 YtpI-like protein DUF4064 PF13273.6 KXS19953.1 - 2.3 8.5 8.3 0.53 10.6 0.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) DUF1691 PF07950.11 KXS19954.1 - 0.0011 19.7 0.3 0.87 10.3 0.0 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF1691) Pkinase PF00069.25 KXS19955.1 - 4.5e-66 222.9 0.0 5.6e-66 222.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS19955.1 - 5.5e-34 117.6 0.0 7.1e-34 117.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXS19955.1 - 4.7e-07 29.4 0.0 7.7e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KXS19955.1 - 0.00051 19.1 0.1 0.00078 18.5 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 KXS19955.1 - 0.00074 18.4 0.0 0.0012 17.7 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KXS19955.1 - 0.0029 17.6 0.0 0.0044 17.0 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KXS19955.1 - 0.023 14.3 0.0 0.29 10.7 0.0 2.3 2 0 0 2 2 2 0 RIO1 family GST_C PF00043.25 KXS19956.1 - 4e-16 59.0 0.0 0.00029 21.0 0.0 3.5 3 0 0 3 3 3 3 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KXS19956.1 - 1.6e-15 57.1 0.0 5.5e-05 23.3 0.0 3.4 3 0 0 3 3 3 3 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KXS19956.1 - 2.6e-15 56.2 0.1 0.00016 21.6 0.0 3.6 3 0 0 3 3 3 3 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 KXS19956.1 - 0.0015 18.2 1.7 2.7 7.8 0.0 3.5 3 0 0 3 3 3 2 Glutathione S-transferase, C-terminal domain Glutaredoxin2_C PF04399.13 KXS19956.1 - 0.02 14.7 0.3 20 5.0 0.0 3.3 3 0 0 3 3 3 0 Glutaredoxin 2, C terminal domain GST_C PF00043.25 KXS19957.1 - 2e-07 31.1 0.0 3.5e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KXS19957.1 - 4.5e-07 30.0 0.0 6.9e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KXS19957.1 - 4.7e-05 23.3 0.0 9e-05 22.4 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin2_C PF04399.13 KXS19957.1 - 0.015 15.1 0.0 0.026 14.4 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain GST_C_6 PF17171.4 KXS19957.1 - 0.13 12.1 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain vATP-synt_AC39 PF01992.16 KXS19958.1 - 5.4e-119 397.6 1.5 6.1e-119 397.5 1.5 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit OTCace PF00185.24 KXS19959.1 - 6.6e-45 153.0 0.0 9e-45 152.6 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.21 KXS19959.1 - 4.9e-39 133.7 0.0 7.5e-39 133.1 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain Sec5 PF15469.6 KXS19960.1 - 2.1e-48 164.6 0.1 4e-48 163.8 0.1 1.5 1 0 0 1 1 1 1 Exocyst complex component Sec5 Dor1 PF04124.12 KXS19960.1 - 1.4e-05 24.0 0.0 3e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Dor1-like family Vps51 PF08700.11 KXS19960.1 - 0.005 16.9 0.0 0.013 15.5 0.0 1.8 1 0 0 1 1 1 1 Vps51/Vps67 Sec15 PF04091.12 KXS19960.1 - 0.049 13.0 0.0 0.13 11.6 0.0 1.7 1 0 0 1 1 1 0 Exocyst complex subunit Sec15-like DUF3337 PF11816.8 KXS19961.1 - 3.5e-15 56.3 0.0 5.5e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3337) WD40 PF00400.32 KXS19961.1 - 3.6e-13 49.7 24.4 4.7e-05 24.1 0.2 7.1 8 0 0 8 8 8 4 WD domain, G-beta repeat VID27 PF08553.10 KXS19961.1 - 0.04 13.0 0.0 0.064 12.3 0.0 1.2 1 0 0 1 1 1 0 VID27 C-terminal WD40-like domain NUDIX PF00293.28 KXS19962.1 - 5.3e-10 39.4 0.0 1.1e-09 38.4 0.0 1.5 1 1 0 1 1 1 1 NUDIX domain NmrA PF05368.13 KXS19963.1 - 5.3e-16 58.9 0.0 6.9e-16 58.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXS19963.1 - 3e-06 27.3 0.0 1.7e-05 24.8 0.0 1.9 1 1 0 1 1 1 1 NAD(P)H-binding Complex1_51K PF01512.17 KXS19963.1 - 0.012 15.5 0.0 0.02 14.7 0.0 1.3 1 0 0 1 1 1 0 Respiratory-chain NADH dehydrogenase 51 Kd subunit Gpr1_Fun34_YaaH PF01184.19 KXS19964.1 - 2.2e-17 63.3 6.3 3.1e-17 62.9 6.3 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Epimerase PF01370.21 KXS19965.1 - 8.4e-11 41.8 0.1 0.00017 21.1 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KXS19965.1 - 1.1e-09 38.2 0.8 1.9e-09 37.4 0.8 1.4 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXS19965.1 - 1.9e-09 37.7 2.1 3.7e-09 36.7 2.1 1.5 1 1 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KXS19965.1 - 0.00017 20.7 0.1 0.00025 20.2 0.1 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KXS19965.1 - 0.00039 19.7 0.1 0.00073 18.8 0.1 1.5 1 0 0 1 1 1 1 Male sterility protein TrkA_N PF02254.18 KXS19965.1 - 0.0065 16.7 0.2 0.011 15.9 0.2 1.3 1 0 0 1 1 1 1 TrkA-N domain Semialdhyde_dh PF01118.24 KXS19965.1 - 0.011 16.2 0.2 0.052 14.0 0.1 2.0 1 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 KXS19965.1 - 0.04 13.1 0.1 0.071 12.2 0.1 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Ldh_1_N PF00056.23 KXS19965.1 - 0.05 13.7 0.2 0.16 12.1 0.1 1.8 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain ADH_zinc_N PF00107.26 KXS19965.1 - 0.075 13.0 0.2 0.23 11.5 0.2 1.8 1 0 0 1 1 1 0 Zinc-binding dehydrogenase NAD_binding_3 PF03447.16 KXS19965.1 - 0.077 13.7 0.8 0.28 11.8 0.1 2.1 2 0 0 2 2 2 0 Homoserine dehydrogenase, NAD binding domain BSP_II PF05432.11 KXS19966.1 - 0.02 14.6 2.1 0.028 14.1 2.1 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Pkinase_Tyr PF07714.17 KXS19969.1 - 0.00022 20.6 0.0 0.00034 20.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXS19969.1 - 0.05 13.0 0.0 0.081 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain Spt5-NGN PF03439.13 KXS19969.1 - 0.13 12.2 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 Early transcription elongation factor of RNA pol II, NGN section Hydrolase_4 PF12146.8 KXS19970.1 - 1.8e-13 50.3 0.0 2.4e-13 49.9 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KXS19970.1 - 2e-13 51.5 0.0 2.9e-13 50.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXS19970.1 - 1.1e-11 45.0 0.9 5.1e-11 42.7 0.9 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KXS19970.1 - 0.0018 17.8 0.3 0.91 9.0 0.3 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Esterase PF00756.20 KXS19970.1 - 0.015 15.0 0.3 0.02 14.6 0.3 1.4 1 1 0 1 1 1 0 Putative esterase Thioesterase PF00975.20 KXS19970.1 - 0.015 15.4 0.2 0.024 14.7 0.2 1.3 1 0 0 1 1 1 0 Thioesterase domain UPF0227 PF05728.12 KXS19970.1 - 0.024 14.6 0.2 0.047 13.6 0.0 1.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) DLH PF01738.18 KXS19970.1 - 0.049 13.2 0.4 0.13 11.8 0.0 1.8 2 0 0 2 2 2 0 Dienelactone hydrolase family LIDHydrolase PF10230.9 KXS19970.1 - 0.06 12.9 0.1 0.15 11.6 0.0 1.5 1 1 1 2 2 2 0 Lipid-droplet associated hydrolase DUF2920 PF11144.8 KXS19970.1 - 0.14 11.3 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) FYVE PF01363.21 KXS19970.1 - 3.7 7.7 10.6 0.26 11.4 0.8 2.7 3 0 0 3 3 3 0 FYVE zinc finger DIOX_N PF14226.6 KXS19971.1 - 6.8e-16 59.1 0.0 1.4e-15 58.1 0.0 1.6 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KXS19971.1 - 1.4e-15 57.6 0.0 2.7e-15 56.7 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MaoC_dehydratas PF01575.19 KXS19972.1 - 3.4e-29 100.9 0.0 6.8e-29 99.9 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 KXS19972.1 - 4.1e-06 27.0 0.0 0.00011 22.3 0.0 2.3 2 1 0 2 2 2 1 N-terminal half of MaoC dehydratase ACBP PF00887.19 KXS19973.1 - 4.6e-30 103.7 1.0 9e-30 102.7 1.0 1.5 1 0 0 1 1 1 1 Acyl CoA binding protein Abhydrolase_6 PF12697.7 KXS19973.1 - 3.6e-17 63.7 0.4 4.9e-17 63.3 0.4 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXS19973.1 - 6.2e-15 55.1 0.7 4.9e-14 52.2 0.7 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KXS19973.1 - 5.1e-12 46.0 1.3 1.2e-08 34.9 0.8 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 KXS19973.1 - 0.088 12.6 0.3 0.24 11.2 0.1 1.8 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase 2-Hacid_dh_C PF02826.19 KXS19975.1 - 1.6e-43 148.2 0.0 2.3e-43 147.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 KXS19975.1 - 0.00023 21.4 0.0 0.00054 20.2 0.0 1.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase ThiF PF00899.21 KXS19975.1 - 0.0035 16.7 0.2 0.007 15.7 0.2 1.4 1 0 0 1 1 1 1 ThiF family AlaDh_PNT_C PF01262.21 KXS19975.1 - 0.056 12.7 0.1 0.37 10.1 0.0 2.1 2 1 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain bZIP_1 PF00170.21 KXS19976.1 - 5.4e-08 32.8 5.1 9.9e-08 32.0 5.1 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KXS19976.1 - 0.00026 21.0 6.5 0.0013 18.7 4.5 2.3 2 0 0 2 2 2 1 Basic region leucine zipper CCDC85 PF10226.9 KXS19976.1 - 0.018 14.7 1.8 0.041 13.6 0.0 2.2 2 0 0 2 2 2 0 CCDC85 family bZIP_Maf PF03131.17 KXS19976.1 - 2.1 8.9 5.2 5.4 7.6 5.2 1.7 1 0 0 1 1 1 0 bZIP Maf transcription factor PALP PF00291.25 KXS19978.1 - 7.1e-09 35.5 0.0 1.2e-08 34.7 0.0 1.4 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme Trypsin PF00089.26 KXS19980.1 - 3.3e-22 79.4 1.1 4.8e-22 78.9 1.1 1.2 1 0 0 1 1 1 1 Trypsin Peptidase_M13_N PF05649.13 KXS19982.1 - 1.3e-100 337.8 0.0 1.9e-100 337.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 KXS19982.1 - 5.2e-64 215.6 0.0 8.6e-64 214.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M13 Pro_CA PF00484.19 KXS19983.1 - 5.8e-49 166.4 0.0 8.4e-49 165.8 0.0 1.2 1 0 0 1 1 1 1 Carbonic anhydrase PI31_Prot_N PF11566.8 KXS19988.1 - 8.6e-33 113.4 0.0 1.1e-32 113.0 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.11 KXS19988.1 - 4.1e-07 31.1 23.8 4.1e-07 31.1 23.8 4.2 3 1 1 5 5 5 1 PI31 proteasome regulator GILT PF03227.16 KXS19989.1 - 7.7e-08 32.5 0.1 2e-07 31.2 0.1 1.7 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) DNA_pol_B PF00136.21 KXS19990.1 - 4e-107 358.8 0.0 5.5e-107 358.3 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 KXS19990.1 - 1.7e-20 73.5 0.0 4.4e-10 39.2 0.0 2.3 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 KXS19990.1 - 2.3e-07 31.1 9.9 2.3e-07 31.1 9.9 2.3 2 0 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta RRM_1 PF00076.22 KXS19991.1 - 1.1e-17 63.6 0.0 2.5e-05 24.0 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SH3_1 PF00018.28 KXS19994.1 - 0.0015 18.1 0.0 0.0028 17.2 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KXS19994.1 - 0.0037 16.9 0.0 0.0056 16.3 0.0 1.2 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KXS19994.1 - 0.012 15.5 0.1 0.018 14.9 0.1 1.3 1 0 0 1 1 1 0 Variant SH3 domain ADH_zinc_N PF00107.26 KXS19996.1 - 3.8e-24 85.1 0.4 7.8e-24 84.1 0.4 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXS19996.1 - 5.3e-23 81.0 3.6 1.2e-22 79.8 3.6 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 KXS19996.1 - 1.3e-05 24.8 0.1 2.7e-05 23.8 0.1 1.5 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus UDPG_MGDP_dh_N PF03721.14 KXS19996.1 - 0.0068 16.0 0.1 0.014 15.0 0.1 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.19 KXS19996.1 - 0.012 15.0 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.6 KXS19996.1 - 0.012 16.6 0.0 0.023 15.7 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Tic110 PF16940.5 KXS19996.1 - 0.14 10.7 1.1 0.22 10.0 1.1 1.2 1 0 0 1 1 1 0 Chloroplast envelope transporter DIOX_N PF14226.6 KXS19997.1 - 1.1e-23 84.2 0.2 3.5e-23 82.6 0.2 1.8 1 1 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KXS19997.1 - 1.8e-20 73.3 0.0 3.4e-20 72.4 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily bZIP_1 PF00170.21 KXS19998.1 - 7.8e-09 35.5 9.5 1e-08 35.1 8.5 1.8 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KXS19998.1 - 4.9e-08 32.9 10.8 1e-07 31.9 10.8 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KXS19998.1 - 0.0088 16.5 5.6 0.016 15.7 5.6 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor Jnk-SapK_ap_N PF09744.9 KXS19998.1 - 0.023 14.9 5.8 0.038 14.2 5.8 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF3958 PF13125.6 KXS19998.1 - 0.039 14.1 3.3 0.065 13.5 3.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3958) HALZ PF02183.18 KXS19998.1 - 0.18 12.0 1.7 0.32 11.2 1.7 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper FUN14 PF04930.15 KXS19999.1 - 9.3e-19 67.6 1.9 1.1e-18 67.4 1.9 1.1 1 0 0 1 1 1 1 FUN14 family Dockerin_1 PF00404.18 KXS19999.1 - 0.0057 16.8 0.0 0.0077 16.4 0.0 1.2 1 0 0 1 1 1 1 Dockerin type I domain EF-hand_5 PF13202.6 KXS19999.1 - 0.051 13.1 0.3 0.093 12.3 0.3 1.4 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.6 KXS19999.1 - 0.083 12.9 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain EF-hand_1 PF00036.32 KXS19999.1 - 0.087 12.4 0.1 0.15 11.6 0.1 1.5 1 0 0 1 1 1 0 EF hand Tyr-DNA_phospho PF06087.12 KXS20000.1 - 3.6e-51 174.4 0.0 4.9e-51 174.0 0.0 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase UIM PF02809.20 KXS20000.1 - 7.8e-07 28.6 15.1 0.0021 17.9 6.0 2.4 2 0 0 2 2 2 2 Ubiquitin interaction motif PLDc_2 PF13091.6 KXS20000.1 - 1.5e-06 28.2 0.0 0.046 13.6 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain Hemerythrin PF01814.23 KXS20001.1 - 1.1e-11 45.4 10.8 5e-11 43.3 10.5 1.9 1 1 1 2 2 2 2 Hemerythrin HHE cation binding domain Importin_rep_3 PF18806.1 KXS20002.1 - 0.0045 17.0 0.1 0.02 14.9 0.0 2.3 2 0 0 2 2 2 1 Importin 13 repeat TetR_C_33 PF13305.6 KXS20002.1 - 0.14 12.9 0.9 4.8 8.0 0.0 3.8 4 0 0 4 4 4 0 Tetracyclin repressor-like, C-terminal domain RasGEF PF00617.19 KXS20002.1 - 0.2 11.9 0.0 0.49 10.6 0.0 1.6 1 0 0 1 1 1 0 RasGEF domain Hemerythrin PF01814.23 KXS20003.1 - 1.9e-10 41.5 0.5 2.8e-10 40.9 0.5 1.3 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain DUF952 PF06108.12 KXS20004.1 - 2.2e-13 50.0 0.0 2.8e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF952) SLAC1 PF03595.17 KXS20005.1 - 4.9e-12 45.7 16.8 7.8e-12 45.1 16.8 1.2 1 1 0 1 1 1 1 Voltage-dependent anion channel tRNA-synt_2b PF00587.25 KXS20006.1 - 5.6e-35 120.9 0.0 1.1e-34 120.0 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 KXS20006.1 - 3.6e-26 91.5 5.8 3.6e-26 91.5 5.8 1.7 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain FapA PF03961.13 KXS20006.1 - 0.14 10.7 2.2 0.2 10.2 2.2 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A V_ATPase_I PF01496.19 KXS20006.1 - 0.46 8.3 1.4 0.61 7.9 1.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CtIP_N PF10482.9 KXS20006.1 - 0.96 9.5 7.8 0.058 13.5 1.7 2.0 2 0 0 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain WAPL PF07814.13 KXS20008.1 - 0.02 13.7 0.0 0.34 9.6 0.0 2.0 2 0 0 2 2 2 0 Wings apart-like protein regulation of heterochromatin AAA_12 PF13087.6 KXS20010.1 - 1.4e-37 129.3 0.0 2.3e-37 128.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KXS20010.1 - 1.1e-20 74.5 0.1 2.3e-11 44.0 0.1 2.4 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KXS20010.1 - 4.1e-07 29.9 0.0 0.00015 21.6 0.0 3.3 3 1 0 3 3 3 1 AAA domain AAA_19 PF13245.6 KXS20010.1 - 1.2e-06 28.9 0.0 4.4e-06 27.1 0.0 2.0 2 1 0 2 2 2 1 AAA domain UvrD-helicase PF00580.21 KXS20010.1 - 0.00036 20.2 0.0 0.00062 19.4 0.0 1.3 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain ResIII PF04851.15 KXS20010.1 - 0.00036 20.6 0.0 0.00079 19.5 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.14 KXS20010.1 - 0.00041 20.3 0.0 0.00085 19.2 0.0 1.5 1 0 0 1 1 1 1 Helicase AAA_22 PF13401.6 KXS20010.1 - 0.0037 17.5 0.0 0.008 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain Terminase_GpA PF05876.12 KXS20010.1 - 0.0075 14.9 0.0 0.022 13.3 0.0 1.7 2 0 0 2 2 2 1 Phage terminase large subunit (GpA) AAA_16 PF13191.6 KXS20010.1 - 0.008 16.6 0.0 0.029 14.8 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain UvrD_C_2 PF13538.6 KXS20010.1 - 0.0085 15.9 0.4 0.054 13.3 0.4 2.4 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA PF00004.29 KXS20010.1 - 0.014 15.8 0.0 0.047 14.1 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DEAD PF00270.29 KXS20010.1 - 0.016 14.9 0.0 0.045 13.5 0.0 1.6 2 0 0 2 2 2 0 DEAD/DEAH box helicase Viral_helicase1 PF01443.18 KXS20010.1 - 0.021 14.6 0.1 2.1 8.0 0.0 2.8 3 1 0 3 3 3 0 Viral (Superfamily 1) RNA helicase AAA_7 PF12775.7 KXS20010.1 - 0.13 11.8 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF2075 PF09848.9 KXS20010.1 - 0.16 11.2 0.1 0.32 10.2 0.0 1.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_24 PF13479.6 KXS20010.1 - 0.18 11.5 0.0 0.31 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KXS20010.1 - 0.19 11.1 0.1 0.32 10.3 0.1 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI zf-C3HC4_3 PF13920.6 KXS20011.1 - 4.9e-14 51.9 7.3 6.8e-14 51.5 7.3 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KXS20011.1 - 4.1e-07 29.8 6.0 6.9e-07 29.0 6.0 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KXS20011.1 - 5.4e-05 23.0 7.1 9.1e-05 22.3 7.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXS20011.1 - 5.6e-05 23.4 6.2 8.5e-05 22.8 6.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KXS20011.1 - 0.011 15.6 6.2 0.017 15.1 6.2 1.3 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KXS20011.1 - 0.052 13.4 8.2 0.098 12.5 8.1 1.5 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 KXS20011.1 - 0.072 12.9 6.3 0.13 12.1 6.3 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-P11 PF03854.14 KXS20011.1 - 0.58 9.9 2.5 1 9.1 2.5 1.4 1 0 0 1 1 1 0 P-11 zinc finger KH_1 PF00013.29 KXS20012.1 - 1.8e-19 69.3 4.7 9e-15 54.3 1.6 2.3 2 0 0 2 2 2 2 KH domain KH_2 PF07650.17 KXS20012.1 - 3.9e-07 29.8 3.3 0.00027 20.7 0.2 2.3 1 1 1 2 2 2 2 KH domain KH_4 PF13083.6 KXS20012.1 - 0.004 17.0 0.1 0.054 13.4 0.0 2.2 2 0 0 2 2 2 1 KH domain Fungal_trans PF04082.18 KXS20013.1 - 5.7e-13 48.5 0.1 8.4e-13 48.0 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.18 KXS20014.1 - 1.8e-09 37.0 0.0 3e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXS20014.1 - 6.2e-07 29.4 6.6 1e-06 28.7 6.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PA_decarbox PF05870.11 KXS20015.1 - 6.1e-23 81.2 0.1 7.3e-23 80.9 0.1 1.1 1 0 0 1 1 1 1 Phenolic acid decarboxylase (PAD) MoaF_C PF17409.2 KXS20015.1 - 2.4e-05 24.0 0.1 3.1e-05 23.6 0.1 1.1 1 0 0 1 1 1 1 MoaF C-terminal domain MoaF PF10703.9 KXS20015.1 - 8.1e-05 22.5 0.0 0.00012 21.9 0.0 1.2 1 0 0 1 1 1 1 MoaF N-terminal domain LRR_12 PF18837.1 KXS20016.1 - 0.052 13.2 0.1 0.099 12.3 0.1 1.4 1 0 0 1 1 1 0 Leucine-rich repeat Herpes_pp85 PF04637.12 KXS20016.1 - 0.74 8.2 2.1 1.4 7.2 2.1 1.4 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) UL17 PF17640.2 KXS20017.1 - 0.13 12.3 0.0 0.32 11.0 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized UL17 PBP1_TM PF14812.6 KXS20017.1 - 0.41 11.1 0.0 0.41 11.1 0.0 1.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Rab3-GTPase_cat PF13890.6 KXS20019.1 - 7.6e-29 100.5 1.3 1.6e-28 99.4 1.3 1.6 1 1 0 1 1 1 1 Rab3 GTPase-activating protein catalytic subunit F-box-like PF12937.7 KXS20021.1 - 0.012 15.4 0.2 0.033 14.1 0.2 1.8 1 0 0 1 1 1 0 F-box-like COX6B PF02297.17 KXS20022.1 - 6.9e-20 71.1 6.7 8.1e-20 70.9 6.7 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb APOBEC_C PF05240.14 KXS20022.1 - 0.0065 16.4 0.7 0.0098 15.8 0.7 1.3 1 0 0 1 1 1 1 APOBEC-like C-terminal domain CHCH PF06747.13 KXS20022.1 - 0.095 12.9 1.0 0.21 11.8 1.0 1.6 1 1 0 1 1 1 0 CHCH domain Helicase_C PF00271.31 KXS20023.1 - 5.9e-23 81.3 0.4 1.2e-22 80.3 0.4 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXS20023.1 - 1.8e-19 70.4 0.0 3.6e-19 69.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KXS20023.1 - 1.4e-16 60.8 0.0 1.5e-15 57.4 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C_2 PF13307.6 KXS20023.1 - 0.048 13.8 0.3 0.54 10.4 0.0 2.2 2 0 0 2 2 2 0 Helicase C-terminal domain DUF2075 PF09848.9 KXS20023.1 - 0.089 12.0 0.0 0.17 11.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Cyt-b5 PF00173.28 KXS20025.1 - 1.6e-07 31.3 0.0 3.6e-07 30.2 0.0 1.7 2 1 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.13 KXS20026.1 - 1.6e-10 41.4 23.8 1.6e-10 41.4 23.8 2.7 2 2 1 3 3 3 1 Fatty acid hydroxylase superfamily DUF3712 PF12505.8 KXS20027.1 - 2.7e-39 134.3 29.3 1.1e-21 77.4 0.8 5.5 5 0 0 5 5 5 4 Protein of unknown function (DUF3712) LEA_2 PF03168.13 KXS20027.1 - 2.1e-08 34.6 23.6 0.0072 16.8 0.2 7.6 8 0 0 8 8 8 5 Late embryogenesis abundant protein VIT PF08487.10 KXS20027.1 - 0.016 15.4 2.2 3 8.1 0.1 3.6 3 0 0 3 3 3 0 Vault protein inter-alpha-trypsin domain F-box-like PF12937.7 KXS20028.1 - 1e-08 34.9 0.3 2.4e-08 33.7 0.3 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXS20028.1 - 0.0013 18.6 0.7 0.0033 17.2 0.7 1.7 1 0 0 1 1 1 1 F-box domain Beta-lactamase PF00144.24 KXS20029.1 - 1e-30 107.1 1.0 2.4e-30 105.9 1.0 1.5 1 1 0 1 1 1 1 Beta-lactamase IBR PF01485.21 KXS20030.1 - 5.8e-17 61.7 27.5 2.9e-11 43.4 0.7 3.6 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain RWD PF05773.22 KXS20030.1 - 3.1e-12 46.8 0.0 5.2e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 RWD domain zf-RING_UBOX PF13445.6 KXS20030.1 - 0.0032 17.4 3.1 0.0032 17.4 3.1 4.5 3 1 1 4 4 4 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KXS20030.1 - 0.0051 16.6 7.1 0.0051 16.6 7.1 5.4 4 2 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXS20030.1 - 0.008 16.5 8.3 0.008 16.5 8.3 4.3 3 2 2 5 5 5 2 Ring finger domain zf-RING_5 PF14634.6 KXS20030.1 - 0.02 14.8 8.0 0.02 14.8 8.0 4.6 3 1 1 4 4 4 0 zinc-RING finger domain FYVE PF01363.21 KXS20030.1 - 1.5 9.0 25.0 0.95 9.6 1.8 3.6 3 0 0 3 3 3 0 FYVE zinc finger zf-RING_11 PF17123.5 KXS20030.1 - 1.6 8.5 15.0 1.1 9.1 8.4 3.6 4 0 0 4 4 4 0 RING-like zinc finger Amidohydro_3 PF07969.11 KXS20031.1 - 1.9e-26 93.6 0.0 2.7e-15 56.8 0.0 2.5 1 1 0 2 2 2 2 Amidohydrolase family Amidohydro_1 PF01979.20 KXS20031.1 - 1.2e-11 44.5 0.2 4.5e-09 36.1 0.2 2.9 1 1 0 1 1 1 1 Amidohydrolase family zf-Tim10_DDP PF02953.15 KXS20032.1 - 3.7e-22 77.8 2.9 5.3e-22 77.2 2.9 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF1178 PF06676.11 KXS20032.1 - 0.014 15.7 0.1 0.018 15.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1178) Mad3_BUB1_I PF08311.12 KXS20032.1 - 0.092 12.7 0.1 0.11 12.5 0.1 1.2 1 0 0 1 1 1 0 Mad3/BUB1 homology region 1 Tyr_Deacylase PF02580.16 KXS20034.1 - 1.3e-52 178.1 0.0 1.5e-52 178.0 0.0 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase DUF4483 PF14825.6 KXS20035.1 - 4.3e-32 111.1 2.2 1.8e-31 109.0 2.2 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4483) Ureidogly_lyase PF04115.12 KXS20036.1 - 9.6e-09 35.3 0.0 0.00016 21.5 0.0 2.1 1 1 1 2 2 2 2 Ureidoglycolate lyase DUF5602 PF18197.1 KXS20036.1 - 0.039 14.5 0.4 0.77 10.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5602) CSN8_PSD8_EIF3K PF10075.9 KXS20037.1 - 5.5e-33 114.0 0.0 9.5e-33 113.2 0.0 1.3 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 KXS20037.1 - 4e-07 29.7 0.1 4.9e-07 29.4 0.1 1.1 1 0 0 1 1 1 1 SAC3/GANP family PCI PF01399.27 KXS20037.1 - 0.042 14.4 0.3 0.28 11.7 0.3 2.3 1 1 0 1 1 1 0 PCI domain Fungal_trans PF04082.18 KXS20038.1 - 1.3e-13 50.6 0.5 1.9e-13 50.0 0.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXS20038.1 - 2.6e-07 30.7 10.9 3.8e-07 30.1 10.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 KXS20039.1 - 1.5e-29 103.0 26.0 1.5e-29 103.0 26.0 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily Corona_NS4 PF03905.13 KXS20039.1 - 0.087 12.9 0.3 0.95 9.5 0.0 2.7 3 0 0 3 3 3 0 Coronavirus non-structural protein NS4 MFS_1 PF07690.16 KXS20040.1 - 0.02 13.8 1.7 0.032 13.2 1.7 1.4 1 0 0 1 1 1 0 Major Facilitator Superfamily MFS_1 PF07690.16 KXS20041.1 - 2e-46 158.6 47.0 2e-46 158.6 47.0 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KXS20041.1 - 1.6e-13 50.0 24.8 2.1e-13 49.6 24.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KXS20041.1 - 9.7e-07 28.0 12.7 9.7e-07 28.0 12.7 4.0 3 2 1 4 4 4 2 Sugar (and other) transporter Pox_A14 PF05767.12 KXS20041.1 - 0.32 11.2 0.1 0.32 11.2 0.1 3.5 4 0 0 4 4 4 0 Poxvirus virion envelope protein A14 TMEM100 PF16311.5 KXS20041.1 - 2.6 7.7 5.5 2.1 7.9 0.3 2.7 2 0 0 2 2 2 0 Transmembrane protein 100 Aminotran_5 PF00266.19 KXS20043.1 - 1.5e-29 103.1 0.0 1.9e-29 102.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 KXS20043.1 - 0.00028 19.5 0.1 0.00042 18.9 0.1 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KXS20043.1 - 0.011 14.9 0.1 0.017 14.3 0.1 1.3 1 1 0 1 1 1 0 Aminotransferase class I and II ORMDL PF04061.14 KXS20044.1 - 3.9e-49 165.9 0.5 4.5e-49 165.8 0.5 1.0 1 0 0 1 1 1 1 ORMDL family DUF2206 PF09971.9 KXS20044.1 - 0.084 11.6 0.7 2.8 6.6 1.4 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2206) CLTH PF10607.9 KXS20045.1 - 2.9e-35 121.3 0.0 4.1e-35 120.9 0.0 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 KXS20045.1 - 2.9e-10 39.7 0.4 6.1e-10 38.7 0.2 1.7 2 0 0 2 2 2 1 LisH zf-NF-X1 PF01422.17 KXS20046.1 - 6.6e-05 22.9 36.0 0.00027 20.9 14.7 13.2 13 2 0 13 13 13 3 NF-X1 type zinc finger Tmemb_cc2 PF10267.9 KXS20046.1 - 0.14 11.2 4.6 0.24 10.5 4.6 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Rad51 PF08423.11 KXS20047.1 - 3e-24 85.7 0.0 1.5e-12 47.4 0.0 2.1 2 0 0 2 2 2 2 Rad51 AAA_25 PF13481.6 KXS20047.1 - 0.14 11.8 0.0 0.39 10.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain Abhydrolase_1 PF00561.20 KXS20048.1 - 2.1e-24 86.6 0.0 1.1e-20 74.4 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXS20048.1 - 2.8e-16 60.8 0.3 4.6e-16 60.1 0.3 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXS20048.1 - 5.5e-08 32.4 0.0 8.2e-08 31.8 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 KXS20048.1 - 0.0013 17.5 0.0 0.0056 15.4 0.0 1.8 2 0 0 2 2 2 1 Ndr family Peptidase_S10 PF00450.22 KXS20048.1 - 0.15 11.5 0.0 0.2 11.0 0.0 1.1 1 0 0 1 1 1 0 Serine carboxypeptidase MTBP_N PF14918.6 KXS20049.1 - 0.11 11.9 3.5 0.38 10.2 3.7 1.7 2 0 0 2 2 2 0 MDM2-binding Med5 PF08689.10 KXS20049.1 - 0.24 9.2 1.1 0.33 8.7 1.1 1.0 1 0 0 1 1 1 0 Mediator complex subunit Med5 MFS_1 PF07690.16 KXS20051.1 - 7.1e-31 107.4 63.5 9.6e-25 87.2 36.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Arm_3 PF16186.5 KXS20051.1 - 0.24 11.0 0.1 0.51 9.9 0.1 1.4 1 0 0 1 1 1 0 Atypical Arm repeat AAA_2 PF07724.14 KXS20052.1 - 9.2e-41 139.8 0.0 1.6e-40 139.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 KXS20052.1 - 4.7e-14 52.9 0.0 1.7e-13 51.2 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 KXS20052.1 - 6.8e-14 51.7 0.0 1.4e-13 50.7 0.0 1.5 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein Mg_chelatase PF01078.21 KXS20052.1 - 7.8e-07 28.7 0.1 0.0017 17.8 0.0 2.4 1 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 KXS20052.1 - 3.7e-05 24.0 0.2 0.0012 19.1 0.2 2.6 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KXS20052.1 - 6.9e-05 22.9 0.1 0.00025 21.0 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 KXS20052.1 - 9e-05 22.2 0.0 0.0051 16.5 0.0 2.4 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_16 PF13191.6 KXS20052.1 - 0.00039 20.8 2.0 0.04 14.3 0.2 3.0 2 1 1 3 3 3 1 AAA ATPase domain NACHT PF05729.12 KXS20052.1 - 0.0012 18.8 0.0 0.23 11.3 0.0 2.3 2 0 0 2 2 2 1 NACHT domain Sigma54_activ_2 PF14532.6 KXS20052.1 - 0.01 16.0 0.0 0.028 14.6 0.0 1.7 1 1 0 1 1 1 0 Sigma-54 interaction domain RuvB_N PF05496.12 KXS20052.1 - 0.01 15.6 0.1 0.16 11.7 0.0 2.6 3 1 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 KXS20052.1 - 0.025 14.1 0.0 0.055 13.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region MCM PF00493.23 KXS20052.1 - 0.035 13.2 0.0 0.061 12.4 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain T2SSE PF00437.20 KXS20052.1 - 0.059 12.4 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein IstB_IS21 PF01695.17 KXS20052.1 - 0.061 13.0 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_21 PF13304.6 KXS20052.1 - 0.07 12.9 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KXS20052.1 - 0.08 12.7 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 KXS20052.1 - 0.18 12.3 0.0 0.37 11.3 0.0 1.5 1 0 0 1 1 1 0 ABC transporter DEAD PF00270.29 KXS20052.1 - 0.19 11.5 0.0 0.45 10.3 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_24 PF13479.6 KXS20052.1 - 0.24 11.1 0.0 0.38 10.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain LRR_6 PF13516.6 KXS20053.1 - 7e-26 88.1 14.8 0.00015 21.6 0.0 9.1 9 0 0 9 9 9 6 Leucine Rich repeat UL16 PF17622.2 KXS20053.1 - 0.0013 18.4 0.5 0.38 10.4 0.1 2.2 1 1 0 2 2 2 2 Viral unique long protein 16 LRR_1 PF00560.33 KXS20053.1 - 0.016 15.7 0.6 77 4.4 0.0 5.1 5 1 0 5 5 5 0 Leucine Rich Repeat SpoU_sub_bind PF08032.12 KXS20053.1 - 0.022 15.0 0.2 0.77 10.1 0.0 3.1 3 1 1 4 4 4 0 RNA 2'-O ribose methyltransferase substrate binding YqhG PF11079.8 KXS20053.1 - 0.16 10.9 0.0 0.27 10.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial protein YqhG of unknown function SapB_1 PF05184.15 KXS20053.1 - 0.28 11.3 2.6 38 4.4 0.1 3.8 4 0 0 4 4 4 0 Saposin-like type B, region 1 adh_short PF00106.25 KXS20054.1 - 2.7e-32 111.8 0.1 3.9e-32 111.3 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXS20054.1 - 6.3e-21 75.0 0.1 1.4e-20 73.9 0.1 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXS20054.1 - 0.0013 18.7 0.1 0.0035 17.3 0.1 1.8 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.10 KXS20054.1 - 0.088 12.2 0.0 14 4.9 0.0 2.6 2 1 0 2 2 2 0 Fungal family of unknown function (DUF1776) GD_AH_C PF04295.13 KXS20056.1 - 0.095 11.5 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 D-galactarate dehydratase / Altronate hydrolase, C terminus zf-CCCH_4 PF18044.1 KXS20057.1 - 7.1e-07 28.9 3.5 1.3e-06 28.1 3.5 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KXS20057.1 - 9.2e-06 25.5 6.5 1.5e-05 24.8 6.5 1.4 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 KXS20057.1 - 0.00035 20.4 2.0 0.00056 19.7 2.0 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Nucleoporin_FG PF13634.6 KXS20057.1 - 0.0012 19.6 118.2 0.0055 17.5 20.9 5.9 2 2 3 5 5 5 3 Nucleoporin FG repeat region zf-CCCH_2 PF14608.6 KXS20057.1 - 0.49 10.9 5.6 1.1 9.8 5.6 1.6 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger TIG PF01833.24 KXS20058.1 - 3.4e-08 33.4 0.0 8e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 IPT/TIG domain Ank_2 PF12796.7 KXS20058.1 - 0.011 16.4 0.0 0.018 15.6 0.0 1.4 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Aminotran_1_2 PF00155.21 KXS20059.1 - 1.1e-43 149.8 0.0 1.5e-43 149.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DUF5310 PF17237.2 KXS20060.1 - 3.1e-07 30.2 0.1 5.3e-07 29.4 0.1 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5310) Fungal_trans PF04082.18 KXS20061.1 - 0.00012 21.2 0.5 0.00019 20.6 0.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_trans_2_3 PF13632.6 KXS20062.1 - 2.9e-26 92.6 5.8 2.9e-26 92.6 5.8 2.1 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KXS20062.1 - 3.7e-17 63.0 0.2 6.5e-17 62.2 0.2 1.4 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KXS20062.1 - 0.14 11.7 0.4 0.81 9.1 0.1 2.0 2 0 0 2 2 2 0 Glycosyl transferase family 21 Mur_ligase_M PF08245.12 KXS20063.1 - 1.7e-07 31.5 0.2 2.6e-05 24.3 0.2 2.9 1 1 0 1 1 1 1 Mur ligase middle domain DNA_methylase PF00145.17 KXS20063.1 - 0.039 13.3 0.0 0.072 12.4 0.0 1.4 1 0 0 1 1 1 0 C-5 cytosine-specific DNA methylase Deltameth_res PF16020.5 KXS20063.1 - 0.17 11.8 0.6 0.41 10.6 0.0 1.8 2 0 0 2 2 2 0 Deltamethrin resistance Exonuc_VII_L PF02601.15 KXS20064.1 - 9.8 5.6 17.8 2 7.9 3.6 2.2 2 0 0 2 2 2 0 Exonuclease VII, large subunit LRR_9 PF14580.6 KXS20065.1 - 1.2e-45 155.1 16.2 1.9e-18 66.6 1.1 5.5 4 1 1 5 5 5 4 Leucine-rich repeat LRR_4 PF12799.7 KXS20065.1 - 5.4e-42 141.1 50.0 5.1e-06 26.7 0.1 12.2 10 2 1 13 13 13 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXS20065.1 - 3.5e-32 109.9 53.0 1.4e-08 34.4 0.3 9.9 5 3 6 11 11 11 10 Leucine rich repeat LRR_2 PF07723.13 KXS20065.1 - 0.023 15.4 1.3 1.4 9.7 0.0 4.4 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_5 PF13306.6 KXS20065.1 - 0.076 13.0 6.4 1 9.3 0.0 4.2 5 0 0 5 5 5 0 BspA type Leucine rich repeat region (6 copies) LRR_6 PF13516.6 KXS20065.1 - 0.14 12.3 26.8 2.5 8.4 0.2 10.2 12 0 0 12 12 12 0 Leucine Rich repeat Mlh1_C PF16413.5 KXS20066.1 - 2.1e-91 306.0 0.0 4.1e-91 305.1 0.0 1.5 2 0 0 2 2 2 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 KXS20066.1 - 4.5e-31 107.0 0.1 8.1e-31 106.2 0.1 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 KXS20066.1 - 1.5e-12 47.6 0.0 3.1e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KXS20066.1 - 3.8e-07 30.6 0.0 1.8e-06 28.4 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Phage_tail_2 PF06199.11 KXS20066.1 - 0.065 13.3 0.0 8.9 6.4 0.0 2.5 2 0 0 2 2 2 0 Phage tail tube protein INSIG PF07281.12 KXS20067.1 - 3.1e-42 144.6 0.2 8.7e-42 143.2 0.2 1.7 1 1 0 1 1 1 1 Insulin-induced protein (INSIG) CrgA PF06781.12 KXS20067.1 - 0.026 14.6 0.6 0.97 9.5 0.0 2.3 2 0 0 2 2 2 0 Cell division protein CrgA PHO4 PF01384.20 KXS20067.1 - 0.29 10.1 7.5 0.049 12.7 3.5 1.7 2 0 0 2 2 2 0 Phosphate transporter family Adaptin_N PF01602.20 KXS20068.1 - 4.7e-99 332.3 3.7 6.8e-99 331.8 3.7 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.6 KXS20068.1 - 1.6e-61 205.9 0.6 3.8e-61 204.7 0.1 2.0 2 0 0 2 2 2 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.12 KXS20068.1 - 2.3e-57 192.8 0.0 4.6e-57 191.8 0.0 1.6 1 0 0 1 1 1 1 Coatomer beta C-terminal region HEAT_2 PF13646.6 KXS20068.1 - 1.9e-09 37.8 4.8 0.0011 19.4 0.0 5.2 2 2 3 5 5 5 3 HEAT repeats Cnd1 PF12717.7 KXS20068.1 - 6.4e-09 36.1 7.4 6e-06 26.4 0.0 3.1 2 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KXS20068.1 - 0.00026 21.0 4.4 3.2 8.2 0.0 5.0 5 0 0 5 5 5 2 HEAT repeat AbiEi_3 PF11459.8 KXS20068.1 - 0.085 12.6 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator, AbiEi antitoxin, Type IV TA system DUF5578 PF17741.1 KXS20068.1 - 0.14 11.6 6.0 7.4 5.9 0.3 3.1 1 1 1 3 3 3 0 Family of unknown function (DUF5578) Arm PF00514.23 KXS20068.1 - 0.18 11.9 1.9 3.8 7.7 0.1 4.1 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Meis_PKNOX_N PF16493.5 KXS20068.1 - 0.95 9.8 5.0 0.86 10.0 1.0 2.7 2 1 1 3 3 3 0 N-terminal of Homeobox Meis and PKNOX1 CH_2 PF06294.11 KXS20069.1 - 5.4e-32 109.8 0.0 1e-31 108.9 0.0 1.5 1 0 0 1 1 1 1 CH-like domain in sperm protein CAMSAP_CH PF11971.8 KXS20069.1 - 1.2e-14 53.8 0.0 1.9e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 CAMSAP CH domain DUF641 PF04859.12 KXS20069.1 - 0.02 15.2 0.1 0.054 13.8 0.1 1.6 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) CH PF00307.31 KXS20069.1 - 0.12 12.6 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 Calponin homology (CH) domain DUF16 PF01519.16 KXS20069.1 - 0.47 11.0 2.1 0.75 10.3 2.1 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF16 Pkinase PF00069.25 KXS20070.1 - 3e-16 59.6 0.0 4.9e-16 58.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS20070.1 - 1.2e-13 51.0 0.0 3.3e-13 49.5 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase MFS_1 PF07690.16 KXS20071.1 - 4.6e-34 117.9 22.5 4.6e-34 117.9 22.5 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 KXS20071.1 - 1.8e-05 23.8 0.7 1.8e-05 23.8 0.7 2.4 2 0 0 2 2 2 1 MFS_1 like family DUF4131 PF13567.6 KXS20071.1 - 1.4 8.5 4.7 7.2 6.2 1.7 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) MCM PF00493.23 KXS20072.1 - 6.7e-100 332.8 0.0 9.9e-100 332.2 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KXS20072.1 - 7.8e-36 122.7 0.1 1.6e-35 121.7 0.1 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KXS20072.1 - 5e-26 90.9 3.5 2.2e-25 88.9 1.1 2.6 2 0 0 2 2 2 1 MCM AAA-lid domain MCM2_N PF12619.8 KXS20072.1 - 6.8e-18 65.4 22.0 6.8e-18 65.4 22.0 3.0 4 0 0 4 4 4 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.6 KXS20072.1 - 2.6e-15 56.9 5.5 2.8e-15 56.8 1.0 3.0 3 0 0 3 3 3 1 MCM N-terminal domain Mg_chelatase PF01078.21 KXS20072.1 - 1.3e-09 37.7 0.1 1.4e-07 31.1 0.0 2.5 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KXS20072.1 - 6.6e-07 29.4 0.0 1.8e-06 28.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KXS20072.1 - 5.1e-05 23.2 0.0 0.00062 19.6 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA PF00004.29 KXS20072.1 - 0.015 15.7 0.0 0.049 14.0 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KXS20072.1 - 0.032 13.9 0.1 0.27 10.9 0.1 2.1 1 1 0 1 1 1 0 Sigma-54 interaction domain Sod_Ni PF09055.11 KXS20072.1 - 0.036 14.6 0.4 0.089 13.4 0.4 1.6 1 0 0 1 1 1 0 Nickel-containing superoxide dismutase AAA_30 PF13604.6 KXS20072.1 - 0.097 12.4 0.6 0.28 10.9 0.1 1.9 2 0 0 2 2 2 0 AAA domain FtsH_ext PF06480.15 KXS20073.1 - 0.33 11.3 2.6 4.4 7.7 0.1 2.6 3 0 0 3 3 3 0 FtsH Extracellular RRM_1 PF00076.22 KXS20075.1 - 7.4e-12 44.9 0.0 1.3e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glyco_hydro_61 PF03443.14 KXS20077.1 - 1.5e-42 145.8 0.0 2.5e-42 145.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.18 KXS20077.1 - 4e-10 39.5 13.8 4e-10 39.5 13.8 2.0 2 0 0 2 2 2 1 Fungal cellulose binding domain Yeast-kill-tox PF09207.11 KXS20077.1 - 0.16 12.6 5.5 0.39 11.4 5.5 1.7 1 0 0 1 1 1 0 Yeast killer toxin peroxidase PF00141.23 KXS20078.1 - 7.2e-30 104.4 0.0 1.4e-29 103.5 0.0 1.4 1 0 0 1 1 1 1 Peroxidase Cyt-b5 PF00173.28 KXS20078.1 - 1.3e-11 44.5 0.0 2.7e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FAD_binding_6 PF00970.24 KXS20078.1 - 2.8e-10 40.4 0.0 1.8e-09 37.8 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain DOMON PF03351.17 KXS20078.1 - 1.9e-09 37.8 0.4 4.4e-09 36.6 0.4 1.5 1 0 0 1 1 1 1 DOMON domain Cytochrom_B561 PF03188.16 KXS20078.1 - 0.0083 16.3 8.3 0.018 15.2 8.3 1.5 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 NAD_binding_1 PF00175.21 KXS20078.1 - 0.011 16.4 0.0 0.033 14.8 0.0 1.8 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain Aminotran_1_2 PF00155.21 KXS20079.1 - 9.5e-83 278.3 0.0 1.1e-82 278.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Lectin_C PF00059.21 KXS20081.1 - 2.5e-07 31.4 0.7 0.012 16.3 0.1 2.7 2 1 0 2 2 2 2 Lectin C-type domain Mucin PF01456.17 KXS20081.1 - 0.013 15.5 19.9 0.023 14.7 19.9 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein MGC-24 PF05283.11 KXS20081.1 - 0.061 13.8 3.5 0.12 12.8 3.5 1.4 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Hfx_Cass5 PF18287.1 KXS20081.1 - 0.063 13.5 0.2 19 5.5 0.0 2.3 2 0 0 2 2 2 0 Integron Cassette Protein Hfx_Cass5 4HBT_3 PF13622.6 KXS20083.1 - 9.4e-16 58.8 2.6 1.9e-14 54.5 0.8 2.3 2 0 0 2 2 2 2 Thioesterase-like superfamily 4HBT PF03061.22 KXS20083.1 - 9.9e-07 29.0 1.5 0.00086 19.6 0.7 2.6 2 0 0 2 2 2 2 Thioesterase superfamily Sugar_tr PF00083.24 KXS20085.1 - 8.8e-115 384.1 27.7 1e-114 383.9 27.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXS20085.1 - 3.1e-23 82.3 40.5 3.7e-20 72.2 29.9 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Phostensin_N PF13916.6 KXS20087.1 - 1.4 9.3 20.7 7.2 7.0 0.2 5.9 6 0 0 6 6 6 0 PP1-regulatory protein, Phostensin N-terminal Lactamase_B PF00753.27 KXS20088.1 - 8e-29 101.1 1.1 1.1e-28 100.6 1.1 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KXS20088.1 - 0.00047 19.7 0.4 0.0039 16.7 0.4 2.2 1 1 0 1 1 1 1 Beta-lactamase superfamily domain APG9 PF04109.16 KXS20089.1 - 2e-129 432.7 0.0 6.3e-89 299.2 4.4 2.9 2 1 0 2 2 2 2 Autophagy protein Apg9 p450 PF00067.22 KXS20090.1 - 1.4e-07 30.6 0.0 1.4e-07 30.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 TPR_1 PF00515.28 KXS20091.1 - 2.7e-13 49.1 0.3 3e-06 26.8 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KXS20091.1 - 4.2e-12 45.2 2.3 5.7e-06 26.0 0.0 3.3 4 0 0 4 4 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 KXS20091.1 - 5.8e-06 26.3 0.0 0.0013 19.0 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 KXS20091.1 - 1.3e-05 24.8 0.0 0.14 11.9 0.0 2.9 2 0 0 2 2 2 2 TPR repeat TPR_8 PF13181.6 KXS20091.1 - 2e-05 24.4 1.0 0.0039 17.3 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 KXS20091.1 - 7.7e-05 23.2 0.1 0.18 12.7 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 KXS20091.1 - 0.00065 19.8 0.0 0.0029 17.7 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat zf-CCHC_2 PF13696.6 KXS20091.1 - 0.0059 16.4 0.4 0.011 15.5 0.4 1.4 1 0 0 1 1 1 1 Zinc knuckle PPP5 PF08321.12 KXS20091.1 - 0.012 15.8 0.1 0.27 11.5 0.0 2.5 2 0 0 2 2 2 0 PPP5 TPR repeat region TPR_7 PF13176.6 KXS20091.1 - 0.028 14.5 0.1 6.1 7.1 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 KXS20091.1 - 0.12 13.1 0.2 6.3 7.7 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 KXS20091.1 - 0.12 12.9 0.0 28 5.3 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Chitin_synth_2 PF03142.15 KXS20093.1 - 1.1e-252 839.3 0.2 1.4e-252 839.0 0.2 1.0 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.6 KXS20093.1 - 1.5e-13 51.2 7.0 6.6e-13 49.0 7.0 2.2 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KXS20093.1 - 2.5e-13 50.4 0.0 6.7e-12 45.8 0.0 2.9 3 1 0 3 3 3 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KXS20093.1 - 3.1e-06 26.8 0.3 0.00031 20.3 0.1 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 KXS20093.1 - 0.003 17.4 0.0 0.051 13.4 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 2 Mito_carr PF00153.27 KXS20094.1 - 1.7e-60 201.0 0.5 6.2e-22 77.3 0.1 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.19 KXS20094.1 - 0.066 13.6 0.0 1.7 9.1 0.0 2.9 1 1 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family PT-VENN PF04829.13 KXS20094.1 - 1.3 9.1 8.0 18 5.5 0.2 3.8 4 0 0 4 4 4 0 Pre-toxin domain with VENN motif Hydrolase_6 PF13344.6 KXS20095.1 - 1e-31 109.0 0.0 4.9e-31 106.8 0.0 1.9 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KXS20095.1 - 3e-18 65.7 0.0 6e-18 64.7 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 KXS20095.1 - 2.3e-12 47.7 0.0 6.2e-12 46.3 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KXS20095.1 - 2.2e-06 27.9 0.1 0.00026 21.1 0.0 2.7 2 1 1 3 3 3 1 Haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.14 KXS20095.1 - 0.0082 15.8 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 HAD superfamily, subfamily IIIB (Acid phosphatase) DivIVA PF05103.13 KXS20096.1 - 0.0028 17.7 7.0 0.0028 17.7 7.0 3.7 2 1 2 4 4 4 1 DivIVA protein TPR_MLP1_2 PF07926.12 KXS20096.1 - 0.0059 16.7 17.3 0.0059 16.7 17.3 4.0 3 1 1 4 4 4 1 TPR/MLP1/MLP2-like protein Fib_alpha PF08702.10 KXS20096.1 - 0.011 15.9 7.7 0.011 15.9 7.7 3.2 2 1 0 3 3 3 0 Fibrinogen alpha/beta chain family DUF3584 PF12128.8 KXS20096.1 - 0.12 9.8 35.8 0.0045 14.6 29.6 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) DUF1759 PF03564.15 KXS20096.1 - 0.24 11.3 3.9 0.42 10.5 2.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1759) Spore_SspJ PF09575.10 KXS20096.1 - 0.34 11.3 3.6 0.16 12.4 0.4 2.1 2 0 0 2 2 2 0 Small spore protein J (Spore_SspJ) Trimer_CC PF08954.11 KXS20096.1 - 0.67 9.6 21.0 0.041 13.4 2.1 4.6 3 1 1 4 4 4 0 Trimerisation motif CCDC92 PF14916.6 KXS20096.1 - 0.7 9.7 6.2 2.1 8.2 0.8 3.0 3 0 0 3 3 3 0 Coiled-coil domain of unknown function Baculo_PEP_C PF04513.12 KXS20096.1 - 3.5 7.7 11.2 3.5 7.7 0.1 3.1 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus KxDL PF10241.9 KXS20096.1 - 4.7 7.6 8.5 9.8 6.5 0.7 3.2 1 1 1 2 2 2 0 Uncharacterized conserved protein KIAA1430 PF13879.6 KXS20097.1 - 1.1e-12 48.6 6.3 1.1e-12 48.6 6.3 2.0 2 0 0 2 2 2 1 KIAA1430 homologue CpcD PF01383.21 KXS20097.1 - 0.014 15.7 0.3 0.047 14.0 0.3 1.9 1 0 0 1 1 1 0 CpcD/allophycocyanin linker domain Pox_polyA_pol_N PF12630.7 KXS20097.1 - 0.14 12.5 0.3 0.3 11.5 0.3 1.5 1 0 0 1 1 1 0 Poxvirus poly(A) polymerase N-terminal domain GTP_EFTU PF00009.27 KXS20098.1 - 2.3e-36 125.2 4.3 1.7e-35 122.4 1.0 3.0 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 KXS20098.1 - 7.2e-30 103.2 0.2 6e-28 97.0 0.1 2.8 2 0 0 2 2 2 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 KXS20098.1 - 9.6e-10 38.6 0.0 2.3e-09 37.3 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 KXS20098.1 - 0.00018 21.0 0.0 0.00038 19.9 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KXS20098.1 - 0.00043 19.8 0.1 0.0025 17.3 0.1 2.1 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 KXS20098.1 - 0.0012 19.1 0.0 0.002 18.3 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase IF2_N PF04760.15 KXS20098.1 - 0.0012 18.6 0.0 0.003 17.3 0.0 1.7 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region FeoB_N PF02421.18 KXS20098.1 - 0.0032 17.0 0.0 0.0079 15.7 0.0 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KXS20098.1 - 0.0082 16.1 0.1 1 9.3 0.0 2.5 1 1 1 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 KXS20098.1 - 0.01 15.9 1.9 3.1 7.8 0.0 3.2 2 1 1 3 3 3 0 Dynamin family MeaB PF03308.16 KXS20098.1 - 0.011 14.7 0.4 0.052 12.5 0.2 2.1 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Ras PF00071.22 KXS20098.1 - 0.012 15.2 0.0 0.021 14.4 0.0 1.4 1 0 0 1 1 1 0 Ras family GTP_EFTU_D4 PF14578.6 KXS20098.1 - 0.014 15.3 0.9 0.067 13.1 0.0 2.5 3 0 0 3 3 3 0 Elongation factor Tu domain 4 MMR_HSR1_Xtn PF16897.5 KXS20098.1 - 0.073 13.1 0.0 0.2 11.7 0.0 1.7 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain GTP_EFTU_D2 PF03144.25 KXS20098.1 - 0.18 12.2 2.0 4.3 7.8 0.0 3.3 3 0 0 3 3 3 0 Elongation factor Tu domain 2 NARP1 PF12569.8 KXS20098.1 - 2.1 7.1 5.0 3 6.7 5.0 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Glutaredoxin PF00462.24 KXS20099.1 - 3.8e-39 132.7 0.0 5.6e-18 64.9 0.0 3.3 3 0 0 3 3 3 2 Glutaredoxin Thioredoxin PF00085.20 KXS20099.1 - 4.4e-14 52.3 0.0 9.1e-14 51.3 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 KXS20099.1 - 0.0001 22.6 0.1 0.056 13.8 0.0 2.5 1 1 1 2 2 2 2 Thioredoxin-like SH3BGR PF04908.15 KXS20099.1 - 0.00014 22.0 0.0 0.052 13.7 0.0 2.6 2 0 0 2 2 2 1 SH3-binding, glutamic acid-rich protein AhpC-TSA PF00578.21 KXS20099.1 - 0.00027 20.8 0.0 0.0015 18.4 0.0 2.2 2 0 0 2 2 2 1 AhpC/TSA family Thioredoxin_2 PF13098.6 KXS20099.1 - 0.00032 21.1 0.0 0.0032 17.9 0.0 2.5 1 1 0 1 1 1 1 Thioredoxin-like domain HyaE PF07449.11 KXS20099.1 - 0.00055 19.9 0.0 0.015 15.2 0.0 2.9 3 1 0 3 3 3 1 Hydrogenase-1 expression protein HyaE RdRP PF05183.12 KXS20099.1 - 0.0047 15.6 0.0 2 7.0 0.0 2.1 1 1 0 2 2 2 2 RNA dependent RNA polymerase Phosducin PF02114.16 KXS20099.1 - 0.043 12.7 0.0 0.079 11.9 0.0 1.3 1 0 0 1 1 1 0 Phosducin EF-hand_13 PF17958.1 KXS20099.1 - 0.057 13.2 0.1 1.4 8.7 0.0 2.6 2 0 0 2 2 2 0 EF-hand domain Ribophorin_II PF05817.14 KXS20100.1 - 5.1e-37 127.7 0.0 6.4e-37 127.4 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II Invasin_D3 PF09134.10 KXS20100.1 - 0.01 16.2 0.6 0.057 13.7 0.1 2.2 2 0 0 2 2 2 1 Invasin, domain 3 Peptidase_M13_N PF05649.13 KXS20101.1 - 1.6e-91 307.9 0.0 2.2e-91 307.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 KXS20101.1 - 3.6e-71 239.0 0.0 6.2e-71 238.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M13 Dpy-30 PF05186.13 KXS20102.1 - 0.035 13.8 0.0 0.066 12.9 0.0 1.4 1 0 0 1 1 1 0 Dpy-30 motif RNA_pol_3_Rpc31 PF11705.8 KXS20102.1 - 0.17 12.1 0.1 0.29 11.4 0.1 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 LPP PF04728.13 KXS20105.1 - 0.00033 21.0 1.9 0.098 13.1 0.0 2.3 2 0 0 2 2 2 2 Lipoprotein leucine-zipper CLZ PF16526.5 KXS20105.1 - 0.048 14.0 0.2 0.048 14.0 0.2 2.3 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Jnk-SapK_ap_N PF09744.9 KXS20105.1 - 0.061 13.6 12.7 3.3 7.9 12.8 2.0 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 TPR_MLP1_2 PF07926.12 KXS20105.1 - 0.18 11.8 12.4 0.23 11.5 7.9 2.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Tropomyosin PF00261.20 KXS20105.1 - 0.32 10.3 16.5 1.7 8.0 15.5 1.9 1 1 0 1 1 1 0 Tropomyosin Spectrin PF00435.21 KXS20105.1 - 0.52 10.8 7.8 0.16 12.5 0.6 2.1 1 1 1 2 2 2 0 Spectrin repeat XhlA PF10779.9 KXS20105.1 - 0.94 9.7 11.0 19 5.6 4.7 3.0 1 1 2 3 3 3 0 Haemolysin XhlA WD40_alt PF14077.6 KXS20105.1 - 1.4 8.9 3.9 8.1 6.4 0.3 3.0 3 0 0 3 3 3 0 Alternative WD40 repeat motif SlyX PF04102.12 KXS20105.1 - 1.8 9.2 9.2 1.6e+02 3.0 9.2 2.8 1 1 0 1 1 1 0 SlyX Fez1 PF06818.15 KXS20105.1 - 2 8.8 10.9 4.6 7.6 10.9 1.5 1 1 0 1 1 1 0 Fez1 DUF4140 PF13600.6 KXS20105.1 - 2 8.9 13.2 3.8 8.0 0.1 2.9 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) Spc24 PF08286.11 KXS20105.1 - 3.8 7.8 8.1 17 5.7 3.9 2.3 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 FAP PF07174.11 KXS20108.1 - 0.71 9.3 12.3 0.91 8.9 12.3 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Cornichon PF03311.14 KXS20111.1 - 8.9e-51 171.3 11.9 1e-50 171.1 11.9 1.0 1 0 0 1 1 1 1 Cornichon protein zf-RING_2 PF13639.6 KXS20112.1 - 9.6e-05 22.6 2.2 9.6e-05 22.6 2.2 2.3 2 0 0 2 2 2 1 Ring finger domain PHD PF00628.29 KXS20112.1 - 0.013 15.4 1.0 0.013 15.4 1.0 2.4 2 0 0 2 2 2 0 PHD-finger zf-ANAPC11 PF12861.7 KXS20112.1 - 5.4 7.1 7.8 21 5.3 7.6 2.1 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Radical_SAM PF04055.21 KXS20114.1 - 2.8e-07 31.1 0.1 5.3e-07 30.2 0.0 1.6 2 0 0 2 2 2 1 Radical SAM superfamily Fer4_12 PF13353.6 KXS20114.1 - 0.00022 21.5 0.3 0.00039 20.7 0.3 1.3 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 KXS20114.1 - 0.0055 16.8 0.1 0.01 16.0 0.1 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain PilN PF05137.13 KXS20114.1 - 0.073 13.2 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Fimbrial assembly protein (PilN) AMP-binding PF00501.28 KXS20115.1 - 2.5e-92 309.7 0.0 3.1e-92 309.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXS20115.1 - 4.2e-16 59.7 0.9 1.2e-15 58.3 0.9 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Peptidase_M16_M PF16187.5 KXS20116.1 - 1.1e-92 310.2 1.0 1.9e-92 309.5 1.0 1.4 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 KXS20116.1 - 1.2e-41 142.2 0.0 4.1e-41 140.4 0.0 2.0 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KXS20116.1 - 2.1e-36 125.6 0.0 1.9e-23 83.5 0.0 3.0 3 0 0 3 3 3 2 Peptidase M16 inactive domain eIF2A PF08662.11 KXS20117.1 - 9.3e-71 237.7 0.0 1.1e-69 234.2 0.0 2.5 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 KXS20117.1 - 0.0012 18.7 4.2 0.75 9.8 0.0 4.7 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat HCV_NS1 PF01560.17 KXS20117.1 - 0.092 11.4 0.1 0.4 9.3 0.0 1.8 2 0 0 2 2 2 0 Hepatitis C virus non-structural protein E2/NS1 p450 PF00067.22 KXS20118.1 - 2.5e-64 217.8 0.0 2.8e-64 217.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 zf-C3HC4_3 PF13920.6 KXS20119.1 - 6.7e-10 38.7 8.9 1.2e-09 37.9 8.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXS20119.1 - 3.8e-05 23.9 5.4 9.4e-05 22.7 5.4 1.7 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 KXS20119.1 - 0.00035 20.4 8.3 0.00074 19.3 8.3 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KXS20119.1 - 0.14 12.2 5.6 0.33 10.9 5.6 1.7 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KXS20119.1 - 3.6 7.8 8.4 1.4 9.2 5.7 1.8 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING KAR9 PF08580.10 KXS20119.1 - 9.4 4.6 17.7 14 4.1 17.7 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Peptidase_S10 PF00450.22 KXS20120.1 - 1.6e-99 334.2 0.0 2e-99 333.9 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Phage_TAC_8 PF10666.9 KXS20120.1 - 0.2 11.9 0.0 0.33 11.2 0.0 1.2 1 0 0 1 1 1 0 Phage tail assembly chaperone protein Gp14 ()A118 DDE_Tnp_4 PF13359.6 KXS20123.1 - 3.1e-15 56.2 0.0 3.9e-15 55.9 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 KXS20123.1 - 0.0019 17.9 0.0 0.0033 17.1 0.0 1.3 1 0 0 1 1 1 1 Transposase DDE domain LupA PF18242.1 KXS20124.1 - 0.23 11.1 0.0 0.45 10.1 0.0 1.5 1 0 0 1 1 1 0 Legionella ubiquitin-specific protease A domain NAD_binding_10 PF13460.6 KXS20126.1 - 8.2e-05 22.6 0.0 0.00016 21.6 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding Ank_2 PF12796.7 KXS20130.1 - 8.5e-39 132.0 0.5 3e-11 43.8 0.1 5.5 1 1 5 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXS20130.1 - 2.4e-30 104.5 0.1 2.6e-06 27.8 0.4 7.3 4 3 3 7 7 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXS20130.1 - 1.3e-23 82.8 6.5 1e-09 38.4 0.4 6.0 4 2 2 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXS20130.1 - 1.3e-23 80.5 2.4 0.049 14.2 0.0 9.0 9 0 0 9 9 9 8 Ankyrin repeat Ank PF00023.30 KXS20130.1 - 5.3e-21 74.1 22.6 6.3e-05 23.2 0.1 9.1 7 2 1 8 8 8 5 Ankyrin repeat CLP1_P PF16575.5 KXS20132.1 - 5.6e-51 173.0 0.0 8.7e-51 172.4 0.0 1.3 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop CLP1_N PF16573.5 KXS20132.1 - 3.1e-26 91.4 0.0 5.6e-26 90.6 0.0 1.4 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor Clp1 PF06807.14 KXS20132.1 - 9.3e-06 26.1 0.0 1.6e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 AAA_24 PF13479.6 KXS20132.1 - 0.0027 17.5 0.0 0.0043 16.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain SRPRB PF09439.10 KXS20132.1 - 0.0097 15.4 0.0 0.021 14.3 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.17 KXS20132.1 - 0.0097 15.7 0.0 0.017 14.9 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein ABC_tran PF00005.27 KXS20132.1 - 0.034 14.6 0.0 0.11 12.9 0.0 1.8 2 0 0 2 2 2 0 ABC transporter AAA_35 PF14516.6 KXS20132.1 - 0.048 12.5 0.0 0.077 11.8 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain CbiA PF01656.23 KXS20132.1 - 0.048 13.7 0.0 0.12 12.5 0.0 1.8 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain PduV-EutP PF10662.9 KXS20132.1 - 0.051 13.3 0.0 0.16 11.7 0.0 1.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 KXS20132.1 - 0.074 13.4 0.0 0.16 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.23 KXS20132.1 - 0.12 12.5 0.0 0.3 11.2 0.0 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KXS20132.1 - 0.14 11.5 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Alk_phosphatase PF00245.20 KXS20134.1 - 1e-92 311.3 0.0 1.7e-92 310.6 0.0 1.3 1 1 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 KXS20134.1 - 1.2e-05 24.8 0.0 4.4e-05 23.0 0.1 1.8 2 0 0 2 2 2 1 Metalloenzyme superfamily Thiolase_N PF00108.23 KXS20136.1 - 2e-87 292.8 2.1 2.9e-87 292.3 2.1 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KXS20136.1 - 5.3e-37 126.2 0.4 2.6e-35 120.7 0.1 2.4 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KXS20136.1 - 9.4e-05 22.1 0.9 0.023 14.3 0.3 2.6 1 1 1 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain CBFD_NFYB_HMF PF00808.23 KXS20137.1 - 1.5e-22 79.6 0.4 3.5e-22 78.4 0.4 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KXS20137.1 - 6.1e-05 23.4 0.1 6.1e-05 23.4 0.1 2.1 2 1 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 KXS20137.1 - 0.0042 17.2 0.7 0.0097 16.0 0.2 1.7 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Bromo_TP PF07524.13 KXS20137.1 - 0.0062 16.5 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated CENP-W PF15510.6 KXS20137.1 - 0.017 15.3 0.1 0.033 14.4 0.1 1.4 1 0 0 1 1 1 0 CENP-W protein IZUMO PF15005.6 KXS20137.1 - 0.11 13.0 4.8 0.1 13.1 3.4 1.5 1 1 1 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated DUF4011 PF13195.6 KXS20137.1 - 0.17 11.8 2.0 0.24 11.3 2.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4011) Lyase_1 PF00206.20 KXS20138.1 - 1e-94 317.5 0.0 1.5e-94 316.9 0.0 1.3 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.6 KXS20138.1 - 6.9e-24 84.4 0.0 1.5e-23 83.3 0.0 1.6 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal Alg6_Alg8 PF03155.15 KXS20139.1 - 1.7e-137 459.4 26.8 2.1e-137 459.0 26.8 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family CLASP_N PF12348.8 KXS20140.1 - 2.9e-31 108.8 1.3 5.3e-31 107.9 0.3 1.9 2 1 0 2 2 2 1 CLASP N terminal Adaptin_N PF01602.20 KXS20140.1 - 0.0014 17.3 0.1 0.0028 16.3 0.1 1.4 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KXS20140.1 - 0.0026 17.8 0.9 0.21 11.7 0.3 3.1 1 1 2 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 KXS20140.1 - 0.0034 17.8 0.2 0.24 11.9 0.0 3.7 3 0 0 3 3 3 1 HEAT-like repeat HEAT PF02985.22 KXS20140.1 - 0.022 15.0 0.6 7.2 7.2 0.1 4.3 4 0 0 4 4 4 0 HEAT repeat MMS19_N PF14500.6 KXS20140.1 - 0.15 11.6 2.9 9.3 5.7 0.2 2.6 3 0 0 3 3 3 0 Dos2-interacting transcription regulator of RNA-Pol-II HEAT_2 PF13646.6 KXS20140.1 - 0.18 12.2 5.0 1.3 9.4 0.1 3.7 3 2 1 4 4 4 0 HEAT repeats AAA PF00004.29 KXS20141.1 - 2.8e-39 134.6 0.0 2.7e-32 111.9 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KXS20141.1 - 6.9e-09 36.3 1.8 0.00057 20.3 0.0 3.9 2 2 2 4 4 4 2 AAA ATPase domain AAA_5 PF07728.14 KXS20141.1 - 2.8e-06 27.4 0.0 0.011 15.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 KXS20141.1 - 0.00068 19.2 0.0 0.08 12.4 0.0 2.5 2 1 0 2 2 2 1 P-loop containing dynein motor region AAA_22 PF13401.6 KXS20141.1 - 0.00084 19.6 0.2 0.038 14.3 0.3 2.8 2 1 0 2 2 2 1 AAA domain NACHT PF05729.12 KXS20141.1 - 0.0064 16.4 0.5 6.4 6.7 0.2 3.6 2 2 0 2 2 2 1 NACHT domain AAA_3 PF07726.11 KXS20141.1 - 0.011 15.6 0.0 6.4 6.7 0.0 2.9 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 KXS20141.1 - 0.011 15.8 0.0 1.1 9.3 0.0 2.5 2 1 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_2 PF07724.14 KXS20141.1 - 0.012 15.8 0.0 0.038 14.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.22 KXS20141.1 - 0.019 15.3 0.0 0.043 14.2 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_30 PF13604.6 KXS20141.1 - 0.025 14.3 0.0 9.2 5.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_lid_3 PF17862.1 KXS20141.1 - 0.026 14.3 0.1 4.4 7.2 0.0 2.8 3 0 0 3 3 3 0 AAA+ lid domain T2SSE PF00437.20 KXS20141.1 - 0.039 13.0 0.0 0.43 9.6 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_18 PF13238.6 KXS20141.1 - 0.04 14.5 0.0 0.26 11.8 0.0 2.3 3 0 0 3 3 3 0 AAA domain IstB_IS21 PF01695.17 KXS20141.1 - 0.059 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein ABC_tran PF00005.27 KXS20141.1 - 0.072 13.6 0.0 0.15 12.6 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_14 PF13173.6 KXS20141.1 - 0.099 12.7 0.0 0.26 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 KXS20141.1 - 0.1 12.3 0.0 0.43 10.3 0.0 2.1 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 KXS20141.1 - 0.13 11.4 0.0 0.74 8.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF815) TIP49 PF06068.13 KXS20141.1 - 0.16 11.2 0.1 0.49 9.5 0.0 1.7 2 0 0 2 2 2 0 TIP49 P-loop domain TFIID-18kDa PF02269.16 KXS20142.1 - 9.5e-16 57.6 0.2 1.6e-15 56.9 0.2 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit CUE PF02845.16 KXS20143.1 - 0.0008 19.1 0.4 0.0021 17.7 0.0 2.0 2 0 0 2 2 2 1 CUE domain EXOSC1 PF10447.9 KXS20144.1 - 2e-16 60.6 2.8 2.6e-13 50.5 0.6 2.2 1 1 1 2 2 2 2 Exosome component EXOSC1/CSL4 ECR1_N PF14382.6 KXS20144.1 - 6.8e-10 38.6 1.5 9.4e-10 38.1 0.2 1.9 2 0 0 2 2 2 1 Exosome complex exonuclease RRP4 N-terminal region S1 PF00575.23 KXS20144.1 - 0.031 14.6 0.1 0.11 12.8 0.1 1.9 1 1 0 1 1 1 0 S1 RNA binding domain ATP-synt_G PF04718.15 KXS20145.1 - 1.5e-17 64.3 0.0 1.8e-17 64.0 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial ATP synthase g subunit Glycos_transf_1 PF00534.20 KXS20147.1 - 7.1e-30 103.8 0.0 1.6e-28 99.3 0.0 2.2 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KXS20147.1 - 1.2e-17 64.4 1.3 1.9e-17 63.8 1.3 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 KXS20147.1 - 6e-14 52.6 0.0 2.2e-13 50.8 0.0 1.9 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KXS20147.1 - 7.8e-09 36.2 2.6 7.8e-09 36.2 2.6 1.7 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 KXS20147.1 - 9.9e-06 25.9 0.0 2.1e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 DAHP_synth_1 PF00793.20 KXS20148.1 - 4.6e-106 353.7 0.0 5.7e-106 353.4 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family Sec2p PF06428.11 KXS20149.1 - 9.5e-18 64.0 15.5 9.5e-18 64.0 15.5 2.5 1 1 1 2 2 2 1 GDP/GTP exchange factor Sec2p Macoilin PF09726.9 KXS20149.1 - 0.029 12.9 6.8 0.039 12.5 6.8 1.1 1 0 0 1 1 1 0 Macoilin family MscS_porin PF12795.7 KXS20149.1 - 0.16 11.5 30.9 0.31 10.6 30.9 1.4 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain V_ATPase_I PF01496.19 KXS20149.1 - 3.4 5.5 10.5 5 4.9 10.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ATG16 PF08614.11 KXS20149.1 - 3.8 7.7 34.4 4 7.6 13.4 2.8 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF572 PF04502.13 KXS20149.1 - 8.8 5.8 11.6 24 4.4 11.6 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF572) CCDC74_C PF14917.6 KXS20151.1 - 0.098 13.2 0.1 0.25 11.8 0.1 1.7 1 0 0 1 1 1 0 Coiled coil protein 74, C terminal ssDBP_DBD PF18361.1 KXS20151.1 - 0.13 12.4 0.0 0.19 11.9 0.0 1.2 1 0 0 1 1 1 0 Single stranded DNA-binding protein ss DNA binding domain PS_pyruv_trans PF04230.13 KXS20153.1 - 1.7e-10 41.3 0.2 5e-10 39.8 0.2 1.7 1 1 0 1 1 1 1 Polysaccharide pyruvyl transferase ATP-synt_D PF01813.17 KXS20154.1 - 0.064 13.1 0.0 7.6 6.3 0.0 2.1 2 0 0 2 2 2 0 ATP synthase subunit D COX14 PF14880.6 KXS20155.1 - 4.8e-07 29.5 0.0 5.3e-07 29.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome oxidase c assembly Fcf1 PF04900.12 KXS20156.1 - 5.5e-28 97.3 0.0 9.9e-28 96.5 0.0 1.4 1 0 0 1 1 1 1 Fcf1 DUF5563 PF17718.1 KXS20156.1 - 0.28 10.7 4.1 0.42 10.2 4.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5563) Dicty_REP PF05086.12 KXS20156.1 - 1.4 6.8 3.0 1.7 6.5 3.0 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SWIRM-assoc_2 PF16496.5 KXS20156.1 - 2.3 7.0 10.0 2.8 6.7 10.0 1.1 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal UQ_con PF00179.26 KXS20157.1 - 2.2e-19 69.5 0.0 3.9e-19 68.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Peptidase_C50 PF03568.17 KXS20158.1 - 2.3e-112 376.0 0.0 2.8e-112 375.7 0.0 1.0 1 0 0 1 1 1 1 Peptidase family C50 CHAT PF12770.7 KXS20158.1 - 1e-05 25.1 0.3 0.0033 16.9 0.0 2.4 2 1 0 3 3 3 2 CHAT domain PK PF00224.21 KXS20159.1 - 9.2e-100 333.9 1.1 1.2e-99 333.5 1.1 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 KXS20159.1 - 2.8e-23 82.4 0.6 1.1e-22 80.5 0.1 2.2 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain Pkinase PF00069.25 KXS20160.1 - 1.2e-55 188.8 0.0 2.3e-42 145.2 0.1 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXS20160.1 - 5.9e-25 88.0 0.0 1.3e-24 86.9 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXS20160.1 - 2e-08 33.9 0.0 2.9e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KXS20160.1 - 2.6e-05 23.7 1.0 4.5e-05 22.9 1.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KXS20160.1 - 0.00012 21.1 0.1 0.00012 21.1 0.1 1.9 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 KXS20160.1 - 0.0025 17.8 0.0 0.0045 16.9 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXS20160.1 - 0.022 13.6 0.0 0.04 12.7 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 KXS20160.1 - 0.044 13.4 0.7 0.094 12.3 0.2 1.7 2 0 0 2 2 2 0 RIO1 family UDPG_MGDP_dh_N PF03721.14 KXS20162.1 - 1.2e-63 214.1 0.1 2.3e-62 209.9 0.0 2.1 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.15 KXS20162.1 - 1.4e-33 115.4 0.2 5e-33 113.7 0.1 2.0 3 0 0 3 3 3 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.19 KXS20162.1 - 1.2e-29 102.3 0.0 2.5e-29 101.3 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain NAD_binding_2 PF03446.15 KXS20162.1 - 0.049 13.8 0.0 0.51 10.5 0.0 2.6 2 1 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase polyprenyl_synt PF00348.17 KXS20163.1 - 1.4e-75 253.7 0.0 3.4e-75 252.4 0.0 1.6 1 1 0 1 1 1 1 Polyprenyl synthetase HEPPP_synt_1 PF07307.11 KXS20163.1 - 0.0029 17.3 0.0 0.0045 16.6 0.0 1.2 1 0 0 1 1 1 1 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 Sec23_trunk PF04811.15 KXS20164.1 - 4.1e-71 239.4 0.0 5.8e-71 238.9 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 KXS20164.1 - 1.9e-28 99.0 0.0 4.1e-28 98.0 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 KXS20164.1 - 1.9e-25 88.6 0.1 4.5e-25 87.4 0.1 1.7 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 KXS20164.1 - 5e-16 58.5 7.6 9.7e-16 57.5 7.6 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 KXS20164.1 - 1.5e-14 53.7 0.2 5.8e-14 51.7 0.2 2.0 1 1 0 1 1 1 1 Gelsolin repeat Tim17 PF02466.19 KXS20165.1 - 7.5e-28 97.1 7.4 9.7e-28 96.8 7.4 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family WD40 PF00400.32 KXS20166.1 - 4.1e-26 90.7 30.6 4.5e-05 24.1 0.0 11.8 13 0 0 13 13 13 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXS20166.1 - 1.3e-18 67.0 0.0 0.00052 20.2 0.1 8.4 4 3 3 9 9 9 4 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 KXS20166.1 - 1.8e-13 50.7 0.0 3.1e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family Ge1_WD40 PF16529.5 KXS20166.1 - 8.7e-07 28.2 0.1 0.033 13.1 0.0 4.0 2 1 1 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 KXS20166.1 - 0.011 15.1 0.2 3.9 6.7 0.0 3.9 3 1 2 5 5 5 0 Neuroblastoma-amplified sequence, N terminal WD40_3 PF15911.5 KXS20166.1 - 0.057 13.4 0.1 0.24 11.4 0.0 2.1 2 0 0 2 2 2 0 WD domain, G-beta repeat DUF1343 PF07075.11 KXS20166.1 - 0.057 12.8 0.0 0.086 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1343) Utp21 PF04192.12 KXS20166.1 - 0.15 11.5 0.1 0.26 10.7 0.1 1.2 1 0 0 1 1 1 0 Utp21 specific WD40 associated putative domain Metallophos PF00149.28 KXS20167.1 - 1.8e-40 139.7 0.1 2.3e-40 139.3 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KXS20167.1 - 7.3e-24 83.9 1.4 9.2e-24 83.6 0.6 1.6 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain PWI PF01480.17 KXS20168.1 - 1.6e-29 102.0 0.1 2.6e-29 101.3 0.1 1.4 1 0 0 1 1 1 1 PWI domain Kinesin PF00225.23 KXS20169.1 - 9.7e-99 330.4 0.5 1.1e-98 330.2 0.5 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KXS20169.1 - 1.3e-18 67.4 0.4 8.2e-18 64.8 0.0 2.2 3 0 0 3 3 3 1 Microtubule binding DEAD PF00270.29 KXS20169.1 - 0.69 9.6 2.9 4.3 7.1 0.5 2.5 1 1 1 2 2 2 0 DEAD/DEAH box helicase Phosducin PF02114.16 KXS20170.1 - 3.7e-14 52.3 0.6 1.8e-10 40.2 0.0 2.2 2 0 0 2 2 2 2 Phosducin Cyclin PF08613.11 KXS20170.1 - 0.0016 18.8 0.0 0.0029 18.0 0.0 1.5 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 KXS20170.1 - 0.041 13.6 0.0 0.096 12.4 0.0 1.6 1 0 0 1 1 1 0 Cyclin, N-terminal domain XPG_N PF00752.17 KXS20171.1 - 1.8e-36 124.6 0.0 3.3e-36 123.8 0.0 1.4 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 KXS20171.1 - 7e-31 106.4 0.0 1.7e-30 105.2 0.0 1.7 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.20 KXS20171.1 - 1.4e-05 25.6 0.0 3.4e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold PIG-H PF10181.9 KXS20172.1 - 4e-13 49.0 0.1 7e-13 48.2 0.1 1.4 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component Vma12 PF11712.8 KXS20173.1 - 3.8e-11 43.2 0.2 1.7e-10 41.1 0.2 2.0 1 1 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase Sigma54_activ_2 PF14532.6 KXS20173.1 - 0.079 13.1 0.9 2.9 8.0 0.0 2.5 2 1 0 2 2 2 0 Sigma-54 interaction domain YqfQ PF14181.6 KXS20173.1 - 0.082 13.1 0.5 0.17 12.1 0.5 1.4 1 0 0 1 1 1 0 YqfQ-like protein UPF0184 PF03670.13 KXS20174.1 - 0.004 17.5 1.9 0.011 16.2 1.9 1.8 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0184) V-SNARE_C PF12352.8 KXS20174.1 - 0.0089 16.3 0.1 0.022 15.0 0.1 1.7 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus CREPT PF16566.5 KXS20174.1 - 0.034 14.3 1.4 0.034 14.3 1.4 2.4 2 1 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour NPV_P10 PF05531.12 KXS20174.1 - 0.18 12.3 6.7 0.35 11.4 3.8 2.7 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein T3SSipB PF16535.5 KXS20174.1 - 0.22 12.0 10.9 0.84 10.1 0.8 2.2 2 0 0 2 2 2 0 Type III cell invasion protein SipB Syntaxin-6_N PF09177.11 KXS20174.1 - 0.36 11.4 9.0 0.19 12.3 5.1 2.1 2 0 0 2 2 2 0 Syntaxin 6, N-terminal DUF1664 PF07889.12 KXS20174.1 - 0.37 10.8 13.5 0.23 11.5 4.2 2.7 2 2 0 2 2 2 0 Protein of unknown function (DUF1664) Herpes_IE2_3 PF03361.14 KXS20174.1 - 0.41 10.5 3.6 11 5.9 0.2 2.2 2 0 0 2 2 2 0 Herpes virus intermediate/early protein 2/3 SNARE PF05739.19 KXS20174.1 - 1.4 9.0 9.3 0.25 11.4 4.4 2.4 2 1 0 2 2 2 0 SNARE domain DUF745 PF05335.13 KXS20174.1 - 2.9 7.6 12.6 0.091 12.5 1.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF745) RasGAP_C PF03836.15 KXS20174.1 - 2.9 8.1 9.4 0.3 11.2 0.5 2.5 2 1 0 2 2 2 0 RasGAP C-terminus TMPIT PF07851.13 KXS20174.1 - 4.8 6.3 9.4 2 7.6 0.3 2.2 2 0 0 2 2 2 0 TMPIT-like protein DUF4559 PF15112.6 KXS20174.1 - 7.8 6.1 14.4 0.38 10.4 3.2 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4559) CCDC23 PF15674.5 KXS20174.1 - 8.2 6.5 11.5 0.33 11.0 2.9 2.6 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 23 PP28 PF10252.9 KXS20177.1 - 3.3e-24 85.1 16.4 5.6e-24 84.4 16.4 1.4 1 0 0 1 1 1 1 Casein kinase substrate phosphoprotein PP28 Cas_Cas1 PF01867.16 KXS20177.1 - 1.3 8.1 6.1 1.6 7.8 6.1 1.1 1 0 0 1 1 1 0 CRISPR associated protein Cas1 Borrelia_P83 PF05262.11 KXS20177.1 - 6.6 5.1 13.5 8.1 4.8 13.5 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein Memo PF01875.17 KXS20178.1 - 3.4e-82 275.6 0.0 4.1e-82 275.4 0.0 1.1 1 0 0 1 1 1 1 Memo-like protein CHORD PF04968.12 KXS20179.1 - 2e-51 172.5 19.8 5e-27 94.4 4.3 2.4 2 0 0 2 2 2 2 CHORD CS PF04969.16 KXS20179.1 - 3.8e-17 63.1 0.6 6.6e-17 62.3 0.6 1.4 1 0 0 1 1 1 1 CS domain Myb_DNA-binding PF00249.31 KXS20180.1 - 6.2e-13 48.7 0.0 6.7e-05 23.0 0.0 3.0 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KXS20180.1 - 1.2e-07 31.9 3.1 0.00014 22.1 0.0 3.0 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KXS20180.1 - 4.1e-07 29.8 2.6 0.019 14.9 0.1 2.6 2 0 0 2 2 2 2 Myb DNA-binding like CLTH PF10607.9 KXS20182.1 - 3.9e-38 130.7 0.2 7.2e-38 129.8 0.2 1.5 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain WD40 PF00400.32 KXS20184.1 - 7.3e-28 96.3 17.2 1.4e-05 25.8 0.0 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXS20184.1 - 1.9e-19 69.8 3.5 1.2e-07 31.9 0.1 4.6 3 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KXS20184.1 - 4.2e-07 30.0 0.1 0.022 14.6 0.0 3.2 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KXS20184.1 - 0.015 14.2 0.8 19 4.1 0.0 3.1 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KXS20184.1 - 0.042 12.5 0.2 0.54 8.8 0.1 2.0 2 0 0 2 2 2 0 Nucleoporin Nup120/160 PH PF00169.29 KXS20185.1 - 1.4e-08 35.2 0.2 2.9e-07 31.0 0.2 2.4 1 1 0 1 1 1 1 PH domain PH_11 PF15413.6 KXS20185.1 - 0.14 12.6 0.1 1 9.8 0.0 2.3 2 0 0 2 2 2 0 Pleckstrin homology domain Ammonium_transp PF00909.21 KXS20186.1 - 4e-106 355.1 28.6 4.8e-106 354.8 28.6 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family RRM_1 PF00076.22 KXS20187.1 - 8.9e-09 35.1 0.0 2e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Hydantoinase_B PF02538.14 KXS20188.1 - 5.2e-222 737.8 0.0 6.9e-222 737.4 0.0 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 KXS20188.1 - 3.1e-101 338.5 0.1 1.1e-100 336.7 0.1 1.9 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 KXS20188.1 - 1.4e-58 197.6 0.2 9.8e-57 191.5 0.0 2.4 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region PE PF00934.20 KXS20189.1 - 0.15 12.4 0.1 0.15 12.4 0.1 5.4 6 1 0 6 6 6 0 PE family TPR_MLP1_2 PF07926.12 KXS20189.1 - 0.18 11.8 134.8 0.88 9.6 11.2 8.6 2 2 5 8 8 8 0 TPR/MLP1/MLP2-like protein Jnk-SapK_ap_N PF09744.9 KXS20190.1 - 0.0052 17.0 6.8 0.0052 17.0 6.8 8.9 1 1 7 10 10 10 3 JNK_SAPK-associated protein-1 APG6_N PF17675.1 KXS20190.1 - 0.0082 16.7 20.0 0.0082 16.7 20.0 8.7 1 1 5 7 7 7 3 Apg6 coiled-coil region DivIC PF04977.15 KXS20190.1 - 0.015 15.1 0.9 0.015 15.1 0.9 13.3 8 3 5 13 13 13 0 Septum formation initiator Filament PF00038.21 KXS20190.1 - 0.53 9.8 121.7 2 7.9 14.7 6.7 2 1 3 5 5 5 0 Intermediate filament protein Leu_zip PF15294.6 KXS20190.1 - 2.2 7.7 99.3 0.04 13.4 11.1 6.3 2 1 4 6 6 6 0 Leucine zipper GST_C_2 PF13410.6 KXS20191.1 - 2.1e-10 40.5 0.1 4.7e-10 39.4 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KXS20191.1 - 6e-10 39.2 0.1 1.4e-09 38.0 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KXS20191.1 - 2.5e-09 37.2 0.0 4.5e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KXS20191.1 - 9.6e-06 25.8 0.0 3.2e-05 24.1 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KXS20191.1 - 0.0016 18.9 0.0 0.0035 17.7 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KXS20191.1 - 0.0024 18.2 0.0 0.0041 17.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain F-box-like PF12937.7 KXS20192.1 - 0.016 15.1 4.5 0.075 12.9 1.7 2.6 2 0 0 2 2 2 0 F-box-like F-box PF00646.33 KXS20192.1 - 0.28 11.1 2.0 0.4 10.6 0.7 2.0 2 0 0 2 2 2 0 F-box domain Flavin_Reduct PF01613.18 KXS20193.1 - 3.9e-29 101.7 0.2 4.9e-29 101.4 0.2 1.1 1 0 0 1 1 1 1 Flavin reductase like domain EB1 PF03271.17 KXS20194.1 - 5.6e-15 55.3 0.1 1.1e-14 54.4 0.1 1.5 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.31 KXS20194.1 - 1.5e-06 28.4 0.1 2.6e-06 27.6 0.1 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain CH_2 PF06294.11 KXS20194.1 - 0.046 13.9 0.1 0.07 13.3 0.1 1.3 1 0 0 1 1 1 0 CH-like domain in sperm protein CCDC106 PF15794.5 KXS20194.1 - 0.14 11.8 1.2 1.1 8.9 0.1 2.3 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 106 Metallophos PF00149.28 KXS20195.1 - 4.6e-34 118.7 1.7 7.1e-34 118.1 1.7 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KXS20195.1 - 0.002 18.6 0.0 0.0037 17.7 0.0 1.4 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain APH PF01636.23 KXS20196.1 - 9.1e-39 133.8 0.0 1.2e-38 133.4 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KXS20196.1 - 5.7e-06 26.1 0.0 9.5e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.20 KXS20196.1 - 3.3e-05 23.3 0.0 6.6e-05 22.4 0.0 1.3 1 1 0 1 1 1 1 Ecdysteroid kinase Kdo PF06293.14 KXS20196.1 - 0.0016 17.9 0.1 0.48 9.7 0.0 2.2 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KXS20196.1 - 0.0028 17.3 0.0 1.7 8.2 0.0 2.2 2 0 0 2 2 2 2 RIO1 family DUF1679 PF07914.11 KXS20196.1 - 0.037 12.9 0.0 0.53 9.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) Pkinase PF00069.25 KXS20196.1 - 0.07 12.5 0.0 0.18 11.1 0.0 1.6 2 0 0 2 2 2 0 Protein kinase domain MFS_1 PF07690.16 KXS20197.1 - 1.4e-30 106.4 55.6 5.9e-26 91.2 36.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily FA_hydroxylase PF04116.13 KXS20198.1 - 8.9e-29 100.5 10.3 8.9e-29 100.5 10.3 2.2 3 0 0 3 3 3 1 Fatty acid hydroxylase superfamily TPR_16 PF13432.6 KXS20200.1 - 0.0003 21.4 0.3 0.00042 20.9 0.3 1.2 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 KXS20200.1 - 0.014 15.5 0.0 0.067 13.3 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 KXS20200.1 - 0.1 13.5 0.1 0.33 11.9 0.1 1.9 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.28 KXS20200.1 - 0.1 12.5 0.0 0.21 11.4 0.0 1.6 2 0 0 2 2 2 0 Tetratricopeptide repeat RasGEF PF00617.19 KXS20202.1 - 1.5e-21 77.4 0.0 2.6e-21 76.6 0.0 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KXS20202.1 - 7.1e-10 39.1 0.1 1.7e-09 37.9 0.1 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif PP2C PF00481.21 KXS20203.1 - 6e-19 68.7 0.0 5.3e-14 52.5 0.0 3.1 2 1 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 KXS20203.1 - 4.9e-05 23.1 0.9 0.00062 19.5 0.6 2.3 2 0 0 2 2 2 1 Protein phosphatase 2C Amidohydro_3 PF07969.11 KXS20204.1 - 1.9e-85 288.2 0.0 2.2e-85 287.9 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 KXS20204.1 - 1.1e-10 41.4 0.0 1.2e-08 34.7 0.0 3.0 2 1 0 2 2 2 2 Amidohydrolase family Aldo_ket_red PF00248.21 KXS20205.1 - 6.3e-51 173.3 0.0 4.2e-43 147.6 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family Sacchrp_dh_NADP PF03435.18 KXS20205.1 - 0.14 12.4 0.0 1 9.6 0.0 2.0 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 KXS20206.1 - 2.1e-23 83.0 0.0 7e-23 81.3 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXS20206.1 - 3.3e-12 46.5 0.0 2.6e-11 43.5 0.0 2.1 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KXS20206.1 - 9e-11 41.3 0.0 1.3e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 KXS20206.1 - 4.9e-07 29.4 0.0 1.9e-06 27.5 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_10 PF13460.6 KXS20206.1 - 1.9e-06 27.9 0.0 2.7e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KXS20206.1 - 2.6e-05 23.5 0.5 0.043 12.9 1.1 3.1 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KXS20206.1 - 3.2e-05 23.2 0.0 4.7e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 KXS20206.1 - 0.0006 19.0 0.0 0.0024 17.1 0.0 1.8 2 0 0 2 2 2 1 Male sterility protein KR PF08659.10 KXS20206.1 - 0.0051 16.7 0.3 0.2 11.5 0.3 2.4 1 1 0 1 1 1 1 KR domain NmrA PF05368.13 KXS20206.1 - 0.06 12.9 0.2 0.27 10.8 0.1 2.0 1 1 1 2 2 2 0 NmrA-like family DapB_N PF01113.20 KXS20206.1 - 0.13 12.4 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus MFS_1_like PF12832.7 KXS20207.1 - 3.6e-29 101.8 1.8 4.4e-26 91.6 0.0 2.1 2 0 0 2 2 2 2 MFS_1 like family MFS_1 PF07690.16 KXS20207.1 - 2.9e-15 56.0 31.9 3.9e-14 52.3 18.6 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KXS20207.1 - 1.7e-05 23.6 0.5 9.7e-05 21.1 0.0 2.3 1 1 1 2 2 2 1 MFS/sugar transport protein LacY_symp PF01306.19 KXS20207.1 - 0.00055 18.8 4.4 0.00066 18.6 2.1 2.1 2 1 0 2 2 2 1 LacY proton/sugar symporter ATG22 PF11700.8 KXS20207.1 - 0.003 16.3 0.0 0.0048 15.6 0.0 1.3 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like Ferric_reduct PF01794.19 KXS20207.1 - 0.029 14.5 3.4 2.4 8.3 0.3 2.8 2 0 0 2 2 2 0 Ferric reductase like transmembrane component BT1 PF03092.16 KXS20207.1 - 0.13 10.5 0.1 0.26 9.5 0.1 1.4 1 0 0 1 1 1 0 BT1 family DEAD PF00270.29 KXS20208.1 - 1.5e-38 132.3 0.0 2.8e-38 131.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXS20208.1 - 7.3e-23 81.0 0.0 1.7e-22 79.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXS20208.1 - 0.016 15.2 0.0 0.034 14.2 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KXS20208.1 - 0.064 12.4 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase CMS1 PF14617.6 KXS20208.1 - 0.065 12.6 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit HAD_SAK_1 PF10307.9 KXS20210.1 - 1.4e-28 100.1 0.0 3.1e-28 99.0 0.0 1.5 1 0 0 1 1 1 1 HAD domain family 1 in Swiss Army Knife RNA repair proteins FAA_hydrolase_N PF09298.11 KXS20210.1 - 0.039 14.1 0.0 0.097 12.9 0.0 1.6 1 0 0 1 1 1 0 Fumarylacetoacetase N-terminal MTHFR PF02219.17 KXS20211.1 - 1e-115 386.0 0.0 1.4e-115 385.6 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase ADH_N_2 PF16884.5 KXS20212.1 - 3e-19 68.9 0.0 6.5e-19 67.8 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 KXS20212.1 - 5.8e-14 52.2 0.0 8.9e-14 51.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase HMG_box PF00505.19 KXS20213.1 - 9e-05 22.8 0.9 0.0043 17.4 0.9 2.4 1 1 0 1 1 1 1 HMG (high mobility group) box Pkinase_Tyr PF07714.17 KXS20214.1 - 6e-85 284.6 0.0 6.4e-46 156.7 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXS20214.1 - 2.4e-81 273.0 0.0 6.9e-44 150.2 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Kinase-like PF14531.6 KXS20214.1 - 1.9e-17 63.5 0.0 5.9e-09 35.6 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 KXS20214.1 - 5.7e-05 22.6 0.0 0.005 16.2 0.0 2.2 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 KXS20214.1 - 0.0022 17.1 0.0 0.15 11.0 0.0 2.1 2 0 0 2 2 2 2 Poxvirus serine/threonine protein kinase APH PF01636.23 KXS20214.1 - 0.0034 17.4 0.2 0.95 9.3 0.0 3.3 3 0 0 3 3 3 1 Phosphotransferase enzyme family RIO1 PF01163.22 KXS20214.1 - 0.11 12.1 0.2 2.1 7.9 0.1 2.2 2 0 0 2 2 2 0 RIO1 family Y_phosphatase PF00102.27 KXS20215.1 - 1.2e-06 28.3 0.0 0.00031 20.4 0.0 2.1 1 1 1 2 2 2 2 Protein-tyrosine phosphatase DSPc PF00782.20 KXS20215.1 - 3.4e-05 23.7 0.0 5.2e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 KXS20215.1 - 0.052 13.7 0.1 0.99 9.5 0.1 2.2 1 1 0 1 1 1 0 Inositol hexakisphosphate Ad_Cy_reg PF16701.5 KXS20215.1 - 0.07 12.9 0.0 0.46 10.2 0.0 1.9 2 0 0 2 2 2 0 Adenylate cyclase regulatory domain AA_permease_2 PF13520.6 KXS20216.1 - 1.6e-18 66.8 35.6 2.5e-18 66.1 35.6 1.3 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXS20216.1 - 1.3e-06 27.3 35.0 3e-06 26.1 35.0 1.6 1 1 0 1 1 1 1 Amino acid permease DUF3593 PF12159.8 KXS20216.1 - 0.0085 16.1 1.6 0.0085 16.1 1.6 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF3593) AA_permease_2 PF13520.6 KXS20217.1 - 3e-20 72.5 49.9 4e-20 72.0 49.9 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXS20217.1 - 2.1e-13 49.7 45.5 2.1e-13 49.7 45.5 2.2 1 1 1 2 2 2 1 Amino acid permease DUF3593 PF12159.8 KXS20217.1 - 0.17 11.9 6.4 0.12 12.4 3.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3593) Ank_2 PF12796.7 KXS20219.1 - 0.0017 18.9 0.0 0.27 11.9 0.0 2.9 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXS20219.1 - 0.0064 16.9 0.0 28 5.7 0.0 3.7 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 KXS20219.1 - 0.015 15.9 0.0 3.1 8.5 0.0 3.1 2 1 0 2 2 2 0 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXS20219.1 - 0.025 14.9 0.0 74 3.8 0.0 3.6 3 0 0 3 3 3 0 Ankyrin repeats (many copies) EPO_TPO PF00758.18 KXS20219.1 - 0.16 12.0 0.2 0.16 12.0 0.2 1.7 2 0 0 2 2 2 0 Erythropoietin/thrombopoietin TAF4 PF05236.14 KXS20220.1 - 2.7e-15 56.9 0.0 1e-13 51.7 0.0 3.1 2 1 0 2 2 2 1 Transcription initiation factor TFIID component TAF4 family TPR_9 PF13371.6 KXS20220.1 - 0.37 11.0 2.3 0.52 10.5 0.0 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Chitin_bind_1 PF00187.19 KXS20221.1 - 5.1e-11 42.9 57.5 1.3e-05 25.6 24.6 4.3 2 1 2 4 4 4 3 Chitin recognition protein Porin_4 PF13609.6 KXS20221.1 - 0.62 9.8 3.4 0.86 9.3 3.4 1.1 1 0 0 1 1 1 0 Gram-negative porin Conotoxin PF02950.17 KXS20221.1 - 10 7.3 14.2 11 7.1 5.1 2.6 2 0 0 2 2 2 0 Conotoxin Na_H_Exchanger PF00999.21 KXS20222.1 - 2.4e-58 197.8 45.3 3.5e-58 197.2 45.3 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family NAD_binding_10 PF13460.6 KXS20223.1 - 3.1e-38 131.5 0.0 3.6e-38 131.3 0.0 1.0 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KXS20223.1 - 2.2e-09 37.2 0.0 3.5e-09 36.6 0.0 1.3 1 1 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 KXS20223.1 - 1.5e-08 34.0 0.1 1.9e-08 33.7 0.1 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 KXS20223.1 - 7.8e-07 28.7 0.1 5.2e-05 22.8 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase Epimerase PF01370.21 KXS20223.1 - 1.7e-05 24.4 0.0 2.1e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 KXS20223.1 - 0.0052 17.2 0.0 0.0083 16.6 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain PAC2 PF09754.9 KXS20223.1 - 0.0083 16.2 0.0 0.0091 16.0 0.0 1.1 1 0 0 1 1 1 1 PAC2 family adh_short_C2 PF13561.6 KXS20223.1 - 0.032 13.8 0.1 0.54 9.8 0.0 2.0 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.15 KXS20223.1 - 0.06 12.5 0.0 0.077 12.1 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Ank_2 PF12796.7 KXS20224.1 - 6.2e-05 23.5 0.1 0.001 19.6 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXS20224.1 - 7.2e-05 22.9 0.1 0.016 15.6 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 KXS20224.1 - 9.2e-05 22.7 0.1 0.11 12.8 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KXS20224.1 - 0.0043 17.4 0.1 0.13 12.7 0.0 2.6 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 KXS20224.1 - 0.11 13.2 0.0 1.6 9.4 0.0 2.3 2 0 0 2 2 2 0 Ankyrin repeats (many copies) MutS_V PF00488.21 KXS20225.1 - 2.8e-59 200.3 0.0 4.7e-59 199.6 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KXS20225.1 - 2e-30 106.5 2.8 3.8e-30 105.5 1.0 2.2 2 0 0 2 2 2 1 MutS domain III MutS_II PF05188.17 KXS20225.1 - 1.2e-08 35.3 0.0 3.1e-08 34.0 0.0 1.7 1 1 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 KXS20225.1 - 6.3e-05 23.2 0.0 0.00028 21.2 0.0 2.1 2 0 0 2 2 2 1 MutS family domain IV AAA_30 PF13604.6 KXS20225.1 - 0.012 15.3 1.3 0.075 12.7 0.0 2.6 2 1 0 2 2 2 0 AAA domain AAA_27 PF13514.6 KXS20225.1 - 0.031 13.9 0.0 0.14 11.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 KXS20225.1 - 0.074 13.6 0.1 0.33 11.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 KXS20225.1 - 0.08 13.0 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 KXS20225.1 - 0.1 12.5 0.0 0.37 10.7 0.0 1.9 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Cupin_8 PF13621.6 KXS20226.1 - 2.1e-59 201.3 0.1 2e-48 165.3 0.2 2.1 2 0 0 2 2 2 2 Cupin-like domain WxL PF13731.6 KXS20226.1 - 0.049 13.6 1.3 0.16 12.0 0.7 2.1 2 0 0 2 2 2 0 WxL domain surface cell wall-binding JmjC PF02373.22 KXS20226.1 - 0.19 12.2 0.1 1.1 9.8 0.1 2.2 1 1 0 1 1 1 0 JmjC domain, hydroxylase PALP PF00291.25 KXS20227.1 - 2.3e-54 184.8 0.2 2.6e-54 184.6 0.2 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Form_Nir_trans PF01226.17 KXS20228.1 - 1.6e-61 207.7 19.2 2e-61 207.3 19.2 1.1 1 0 0 1 1 1 1 Formate/nitrite transporter PHD PF00628.29 KXS20229.1 - 4.9e-10 39.1 5.4 4.9e-10 39.1 5.4 1.6 2 0 0 2 2 2 1 PHD-finger BAH PF01426.18 KXS20229.1 - 0.0044 16.9 0.0 0.0067 16.3 0.0 1.3 1 0 0 1 1 1 1 BAH domain zf-CW PF07496.15 KXS20229.1 - 0.017 15.1 2.4 0.046 13.7 2.4 1.7 1 0 0 1 1 1 0 CW-type Zinc Finger PHD_2 PF13831.6 KXS20229.1 - 0.089 12.4 3.2 0.27 10.8 3.2 1.8 1 1 0 1 1 1 0 PHD-finger AA_kinase PF00696.28 KXS20230.1 - 9.9e-40 136.6 0.0 1.8e-39 135.8 0.0 1.4 1 0 0 1 1 1 1 Amino acid kinase family ACT PF01842.25 KXS20230.1 - 5.7e-15 54.8 0.5 1.2e-08 34.5 0.1 2.6 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.6 KXS20230.1 - 3.3e-11 42.8 1.9 2.4e-08 33.7 0.4 2.6 2 0 0 2 2 2 2 ACT domain IPK PF03770.16 KXS20231.1 - 6e-43 147.0 0.0 9.4e-43 146.4 0.0 1.3 1 1 0 1 1 1 1 Inositol polyphosphate kinase FA_hydroxylase PF04116.13 KXS20232.1 - 5e-21 75.4 8.7 5e-21 75.4 8.7 2.0 2 1 1 3 3 3 1 Fatty acid hydroxylase superfamily Imm-NTF2-2 PF15631.6 KXS20232.1 - 0.085 13.1 0.0 0.47 10.7 0.0 2.0 2 0 0 2 2 2 0 NTF2 fold immunity protein TrbC PF04956.13 KXS20232.1 - 1.5 9.1 3.6 1.1 9.5 0.1 2.1 2 0 0 2 2 2 0 TrbC/VIRB2 family Peptidase_C65 PF10275.9 KXS20233.1 - 1.9e-05 24.2 0.2 0.097 12.1 0.1 2.3 1 1 1 2 2 2 2 Peptidase C65 Otubain OTU PF02338.19 KXS20233.1 - 0.0014 19.1 0.0 0.0023 18.4 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease DUF3759 PF12585.8 KXS20234.1 - 1.8e-09 37.5 2.9 2e-09 37.3 2.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) YopE_N PF09020.10 KXS20235.1 - 0.14 12.4 3.3 0.96 9.7 2.4 2.2 1 1 1 2 2 2 0 YopE, N terminal WD40 PF00400.32 KXS20237.1 - 9.6e-13 48.4 23.6 2.1e-07 31.5 0.5 5.1 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXS20237.1 - 4.4e-07 30.1 0.2 0.077 13.3 0.0 3.9 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain zf-NF-X1 PF01422.17 KXS20238.1 - 7e-08 32.4 50.3 1.2e-05 25.2 12.4 12.6 13 0 0 13 13 13 7 NF-X1 type zinc finger DUF4777 PF16007.5 KXS20239.1 - 0.077 13.3 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4777) Pro_Al_protease PF02983.14 KXS20239.1 - 0.091 12.8 0.4 0.21 11.7 0.2 1.7 2 0 0 2 2 2 0 Alpha-lytic protease prodomain Fungal_trans PF04082.18 KXS20240.1 - 1e-12 47.7 0.8 6.3e-11 41.8 0.6 2.0 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KXS20241.1 - 1.3e-08 34.8 10.3 2e-08 34.2 10.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NMO PF03060.15 KXS20242.1 - 8.9e-28 97.6 0.9 3.3e-22 79.3 0.1 2.2 2 0 0 2 2 2 2 Nitronate monooxygenase IMPDH PF00478.25 KXS20242.1 - 9.9e-06 24.8 0.0 9.9e-06 24.8 0.0 1.8 3 0 0 3 3 3 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KXS20242.1 - 0.0045 16.1 1.8 0.0053 15.8 0.0 1.8 2 0 0 2 2 2 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 KXS20242.1 - 0.015 14.5 0.1 0.029 13.5 0.1 1.5 1 0 0 1 1 1 0 Conserved region in glutamate synthase ThiG PF05690.14 KXS20242.1 - 0.06 12.6 0.0 0.095 12.0 0.0 1.2 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG Mur_ligase_M PF08245.12 KXS20244.1 - 1.3e-07 31.8 0.0 5e-07 29.9 0.0 1.9 1 1 0 1 1 1 1 Mur ligase middle domain 2OG-FeII_Oxy_3 PF13640.6 KXS20245.1 - 5.5e-11 43.2 0.0 1.2e-10 42.1 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-H2C2_2 PF13465.6 KXS20247.1 - 7.3e-14 51.5 20.7 1.1e-05 25.7 0.6 5.0 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.26 KXS20247.1 - 2.8e-06 27.5 21.8 0.0012 19.2 1.5 4.2 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXS20247.1 - 0.00021 21.9 20.6 0.27 12.2 0.9 4.6 4 0 0 4 4 4 4 C2H2-type zinc finger FOXP-CC PF16159.5 KXS20247.1 - 0.77 10.4 4.8 0.91 10.2 0.9 2.9 2 1 1 3 3 3 0 FOXP coiled-coil domain UQ_con PF00179.26 KXS20248.1 - 4.9e-36 123.5 0.1 5.7e-36 123.2 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UFC1 PF08694.11 KXS20248.1 - 0.0016 18.1 0.0 0.002 17.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-fold modifier-conjugating enzyme 1 UEV PF05743.13 KXS20248.1 - 0.029 14.2 0.1 0.039 13.8 0.1 1.2 1 0 0 1 1 1 0 UEV domain APH PF01636.23 KXS20250.1 - 4.4e-42 144.6 0.0 5.8e-42 144.3 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KXS20250.1 - 1.8e-07 31.0 0.0 2.6e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 KXS20250.1 - 2.1e-05 24.2 0.0 0.11 12.0 0.0 2.3 2 0 0 2 2 2 2 RIO1 family EcKinase PF02958.20 KXS20250.1 - 0.0035 16.7 0.0 0.006 15.9 0.0 1.4 1 0 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.11 KXS20250.1 - 0.0094 14.9 0.0 0.014 14.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) KTI12 PF08433.10 KXS20251.1 - 2.3e-61 207.7 0.0 5.5e-61 206.4 0.0 1.5 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 KXS20251.1 - 3.3e-10 40.3 0.0 5.4e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain GMC_oxred_N PF00732.19 KXS20252.1 - 1.7e-62 211.5 0.0 2.1e-62 211.2 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXS20252.1 - 2.3e-38 131.9 0.1 4.7e-38 130.9 0.1 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KXS20252.1 - 0.00068 18.8 0.3 0.085 11.9 0.2 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 KXS20252.1 - 0.00069 18.8 0.1 0.0013 17.9 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 KXS20252.1 - 0.0011 18.7 0.1 0.0083 15.8 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXS20252.1 - 0.0012 19.1 0.1 0.0031 17.7 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXS20252.1 - 0.0052 16.0 0.0 0.024 13.9 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXS20252.1 - 0.0073 15.6 0.1 0.016 14.5 0.1 1.5 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 KXS20252.1 - 0.23 10.1 0.1 0.35 9.5 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Rab5ip PF07019.12 KXS20253.1 - 0.014 16.0 0.1 0.023 15.3 0.1 1.3 1 0 0 1 1 1 0 Rab5-interacting protein (Rab5ip) ZZ PF00569.17 KXS20255.1 - 1.9e-09 37.2 3.4 2.8e-09 36.6 3.4 1.2 1 0 0 1 1 1 1 Zinc finger, ZZ type PUB PF09409.10 KXS20256.1 - 2.7e-15 56.1 0.0 4.6e-15 55.3 0.0 1.4 1 0 0 1 1 1 1 PUB domain Ice_nucleation PF00818.17 KXS20256.1 - 3.7 7.8 6.6 24 5.3 1.5 2.9 2 0 0 2 2 2 0 Ice nucleation protein repeat MFS_1 PF07690.16 KXS20258.1 - 5.8e-15 55.1 2.9 7.3e-15 54.7 2.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 KXS20258.1 - 8.8e-08 31.1 0.9 1.2e-07 30.7 0.9 1.3 1 0 0 1 1 1 1 MFS/sugar transport protein Sugar_tr PF00083.24 KXS20258.1 - 1.3e-06 27.6 4.6 2e-06 27.0 4.7 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter PNP_UDP_1 PF01048.20 KXS20259.1 - 2.2e-38 131.8 0.4 2.6e-38 131.6 0.4 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily HMGL-like PF00682.19 KXS20260.1 - 2.5e-54 184.6 0.0 3e-54 184.3 0.0 1.1 1 0 0 1 1 1 1 HMGL-like Cyt-b5 PF00173.28 KXS20261.1 - 1.5e-13 50.7 0.0 3.7e-13 49.4 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_desaturase PF00487.24 KXS20261.1 - 8.1e-08 32.4 17.0 2.5e-07 30.8 17.0 1.9 1 1 0 1 1 1 1 Fatty acid desaturase bZIP_1 PF00170.21 KXS20262.1 - 1.2e-06 28.6 6.9 1.2e-06 28.6 6.9 3.7 2 1 2 4 4 4 1 bZIP transcription factor bZIP_2 PF07716.15 KXS20262.1 - 9.9e-05 22.3 5.8 9.9e-05 22.3 5.8 4.2 2 1 2 4 4 4 2 Basic region leucine zipper KASH_CCD PF14662.6 KXS20262.1 - 0.0021 17.9 4.9 0.0021 17.9 4.9 2.7 3 0 0 3 3 3 1 Coiled-coil region of CCDC155 or KASH Shugoshin_N PF07558.11 KXS20262.1 - 0.011 15.5 2.5 2.4 8.1 0.0 2.4 1 1 1 2 2 2 0 Shugoshin N-terminal coiled-coil region ZapB PF06005.12 KXS20262.1 - 0.015 15.7 4.0 0.015 15.7 4.0 3.6 3 1 0 3 3 3 0 Cell division protein ZapB YabA PF06156.13 KXS20262.1 - 0.081 13.6 8.0 1.5 9.5 6.3 2.9 2 1 0 2 2 2 0 Initiation control protein YabA HALZ PF02183.18 KXS20262.1 - 0.12 12.6 6.9 0.49 10.7 0.1 3.0 2 1 1 3 3 3 0 Homeobox associated leucine zipper TMF_DNA_bd PF12329.8 KXS20262.1 - 3.8 7.6 14.8 0.066 13.2 3.6 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding V_ATPase_I PF01496.19 KXS20262.1 - 4.1 5.2 8.2 8.4 4.2 8.2 1.5 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family NAD_binding_2 PF03446.15 KXS20263.1 - 6.8e-32 110.8 0.3 1.8e-31 109.4 0.3 1.7 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KXS20263.1 - 9.9e-23 80.7 0.0 1.8e-22 79.8 0.0 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 KXS20263.1 - 9.9e-06 26.1 0.0 1.9e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 KXS20263.1 - 0.047 13.1 0.0 0.079 12.3 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PDH PF02153.17 KXS20263.1 - 0.18 10.7 0.2 0.31 10.0 0.2 1.3 1 0 0 1 1 1 0 Prephenate dehydrogenase Cir_N PF10197.9 KXS20264.1 - 0.13 12.4 1.3 0.22 11.7 1.3 1.3 1 0 0 1 1 1 0 N-terminal domain of CBF1 interacting co-repressor CIR HMMR_C PF15908.5 KXS20265.1 - 1.4e-10 41.6 6.5 1.4e-10 41.6 6.5 11.8 5 4 7 13 13 13 2 Hyaluronan mediated motility receptor C-terminal Baculo_PEP_C PF04513.12 KXS20265.1 - 0.00049 20.1 90.1 0.28 11.2 3.4 13.9 6 3 8 14 14 14 6 Baculovirus polyhedron envelope protein, PEP, C terminus BLOC1_2 PF10046.9 KXS20265.1 - 0.00061 20.0 0.8 0.00061 20.0 0.8 19.8 6 5 15 24 24 24 3 Biogenesis of lysosome-related organelles complex-1 subunit 2 HOOK PF05622.12 KXS20265.1 - 0.00086 17.6 7.1 0.00086 17.6 7.1 10.2 1 1 6 9 9 9 5 HOOK protein Atg14 PF10186.9 KXS20265.1 - 0.0011 18.1 26.3 0.002 17.3 8.7 14.1 1 1 12 13 13 13 3 Vacuolar sorting 38 and autophagy-related subunit 14 Filament PF00038.21 KXS20265.1 - 0.0015 18.2 28.6 0.0015 18.2 28.6 13.8 1 1 7 11 11 11 3 Intermediate filament protein AAA_13 PF13166.6 KXS20265.1 - 0.0017 17.1 14.0 0.0017 17.1 14.0 11.4 1 1 12 13 13 13 8 AAA domain YvrJ PF12841.7 KXS20265.1 - 0.37 10.4 1.4 7.3 6.2 0.0 4.2 3 0 0 3 3 3 0 YvrJ protein family DUF3563 PF12086.8 KXS20265.1 - 2.1 8.2 12.3 0.1 12.3 1.9 4.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3563) Spc7 PF08317.11 KXS20265.1 - 4.2 6.2 295.9 0.013 14.5 10.7 16.4 1 1 16 17 17 17 0 Spc7 kinetochore protein MmlI PF09448.10 KXS20266.1 - 0.00059 20.3 0.0 0.001 19.5 0.0 1.4 1 0 0 1 1 1 1 Methylmuconolactone methyl-isomerase GTP_EFTU PF00009.27 KXS20267.1 - 3.9e-40 137.5 0.0 6.2e-40 136.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFTUD2 PF16004.5 KXS20267.1 - 5.2e-37 127.1 1.2 9.6e-37 126.3 1.2 1.4 1 0 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_IV PF03764.18 KXS20267.1 - 9e-24 83.6 0.0 2.2e-23 82.3 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 KXS20267.1 - 1.6e-23 82.6 0.0 4.3e-23 81.1 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KXS20267.1 - 3e-09 37.1 0.3 6.9e-09 36.0 0.3 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 KXS20267.1 - 1.9e-07 31.1 0.0 5.5e-07 29.6 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 KXS20267.1 - 0.00034 20.7 0.0 0.00082 19.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.18 KXS20267.1 - 0.022 14.0 0.0 0.14 11.4 0.0 1.9 1 1 0 2 2 2 0 Septin SRPRB PF09439.10 KXS20267.1 - 0.059 12.8 0.1 0.42 10.0 0.0 2.3 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit TsaE PF02367.17 KXS20267.1 - 0.11 12.5 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SPX PF03105.19 KXS20268.1 - 2.7e-15 57.2 6.7 1.1e-13 51.9 6.7 2.0 1 1 0 1 1 1 1 SPX domain DUF3283 PF11686.8 KXS20268.1 - 0.23 11.3 2.4 0.5 10.3 2.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3283) Type2_restr_D3 PF16902.5 KXS20268.1 - 0.32 10.9 1.2 0.64 10.0 0.1 2.1 3 0 0 3 3 3 0 Type-2 restriction enzyme D3 domain GARP PF16731.5 KXS20268.1 - 0.6 9.8 5.0 2.2 8.0 1.4 2.2 2 0 0 2 2 2 0 Glutamic acid/alanine-rich protein of Trypanosoma EXS PF03124.14 KXS20269.1 - 4.6e-47 161.0 10.0 5.1e-47 160.8 10.0 1.0 1 0 0 1 1 1 1 EXS family MFS_1 PF07690.16 KXS20271.1 - 1.6e-24 86.5 23.0 2.1e-24 86.1 23.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KXS20271.1 - 3.5e-11 42.2 9.4 4.5e-11 41.9 9.4 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 KXS20271.1 - 0.00017 20.0 1.9 0.016 13.5 0.0 2.1 2 0 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family TPR_12 PF13424.6 KXS20272.1 - 0.0053 17.0 6.2 0.26 11.6 0.8 3.9 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 KXS20272.1 - 0.36 11.2 4.5 0.52 10.7 0.2 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 KXS20272.1 - 0.62 10.0 2.6 5.9 6.9 0.1 3.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 KXS20272.1 - 0.67 10.2 6.3 8.7 6.7 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 KXS20272.1 - 1.3 9.0 5.4 25 4.9 0.0 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat MBOAT PF03062.19 KXS20273.1 - 5.2e-44 151.0 22.0 1e-43 150.0 22.0 1.5 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family DUF4464 PF14713.6 KXS20274.1 - 9.8e-97 322.9 0.1 1.2e-96 322.7 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4464) XRN_N PF03159.18 KXS20275.1 - 4.8e-49 167.0 0.0 5.6e-49 166.8 0.0 1.0 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus MFS_1 PF07690.16 KXS20276.1 - 3e-15 56.0 33.4 1.2e-14 54.1 32.5 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Nepo_coat PF03391.15 KXS20276.1 - 0.16 11.5 0.6 0.97 8.9 0.2 2.3 2 1 0 2 2 2 0 Nepovirus coat protein, central domain Staphylcoagulse PF04022.12 KXS20276.1 - 0.16 11.6 0.6 0.36 10.4 0.6 1.6 1 0 0 1 1 1 0 Staphylocoagulase repeat MFS_1 PF07690.16 KXS20277.1 - 1.6e-22 79.9 39.4 1.1e-21 77.1 39.5 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily CcmD PF04995.14 KXS20277.1 - 0.043 13.9 0.2 0.13 12.4 0.2 1.8 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) HSP70 PF00012.20 KXS20278.1 - 3.8e-48 164.1 0.0 1.5e-17 63.0 0.0 4.1 4 0 0 4 4 4 4 Hsp70 protein Blt1 PF12754.7 KXS20278.1 - 4.9 7.4 11.2 1.7 9.0 4.6 3.0 3 0 0 3 3 3 0 Blt1 N-terminal domain UTRA PF07702.13 KXS20279.1 - 0.072 12.9 0.0 0.12 12.2 0.0 1.4 1 1 0 1 1 1 0 UTRA domain ABC_tran PF00005.27 KXS20280.1 - 4.2e-20 72.7 0.0 7e-20 71.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 KXS20280.1 - 1.1e-11 44.5 20.0 1.1e-11 44.5 20.0 1.6 2 0 0 2 2 2 1 ABC-2 type transporter AAA_29 PF13555.6 KXS20280.1 - 0.00017 21.2 0.8 0.00094 18.9 0.0 2.2 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.6 KXS20280.1 - 0.00064 19.6 0.1 0.089 12.6 0.0 2.2 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KXS20280.1 - 0.0073 16.2 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 KXS20280.1 - 0.03 14.7 0.0 0.068 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 KXS20280.1 - 0.049 14.2 0.0 0.094 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KXS20280.1 - 0.05 14.1 0.0 0.092 13.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KXS20280.1 - 0.057 13.0 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 KXS20280.1 - 0.097 12.6 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_22 PF13401.6 KXS20280.1 - 0.1 12.9 0.0 0.21 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KXS20280.1 - 0.11 12.2 0.0 2.9 7.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 KXS20280.1 - 0.17 11.6 0.1 0.45 10.2 0.0 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_33 PF13671.6 KXS20280.1 - 0.2 11.8 0.0 0.45 10.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC2_membrane PF01061.24 KXS20281.1 - 4.8e-25 88.2 25.7 4.8e-25 88.2 25.7 2.2 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 KXS20281.1 - 4.7e-19 69.3 0.0 8.8e-19 68.4 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KXS20281.1 - 0.00051 20.0 0.0 0.088 12.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KXS20281.1 - 0.0011 19.3 0.0 0.0021 18.4 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 KXS20281.1 - 0.0025 17.5 0.1 0.0089 15.8 0.1 1.9 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 KXS20281.1 - 0.016 15.5 0.0 0.032 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KXS20281.1 - 0.021 14.7 0.2 0.039 13.8 0.2 1.3 1 0 0 1 1 1 0 RsgA GTPase Rad17 PF03215.15 KXS20281.1 - 0.051 13.5 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_30 PF13604.6 KXS20281.1 - 0.066 12.9 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KXS20281.1 - 0.069 13.7 0.0 0.15 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KXS20281.1 - 0.077 13.2 0.1 0.16 12.2 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KXS20281.1 - 0.13 12.4 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KXS20281.1 - 0.14 12.6 0.1 0.25 11.8 0.1 1.3 1 0 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 KXS20281.1 - 0.16 11.7 0.1 1.1 8.9 0.1 2.0 2 0 0 2 2 2 0 Cytidylate kinase DUF4201 PF13870.6 KXS20284.1 - 1.3e-43 148.8 24.5 1.3e-43 148.8 24.5 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4201) Sec34 PF04136.15 KXS20284.1 - 1.9 8.3 18.7 0.33 10.8 2.6 3.3 2 1 1 3 3 3 0 Sec34-like family bZIP_1 PF00170.21 KXS20284.1 - 4.2 7.5 28.4 0.13 12.3 1.9 4.7 3 2 1 4 4 4 0 bZIP transcription factor Fez1 PF06818.15 KXS20284.1 - 6 7.3 34.8 8.9 6.7 21.4 2.8 1 1 1 2 2 2 0 Fez1 zf-C4 PF00105.18 KXS20286.1 - 0.35 11.3 6.6 0.085 13.3 2.9 1.8 1 1 1 2 2 2 0 Zinc finger, C4 type (two domains) Glyco_hydro_43 PF04616.14 KXS20288.1 - 3.6e-69 233.2 3.8 5.1e-69 232.8 3.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 KXS20288.1 - 0.0017 18.1 0.0 0.0037 17.0 0.0 1.6 1 1 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain SNF2_N PF00176.23 KXS20289.1 - 3.2e-66 223.4 0.0 7.5e-66 222.2 0.0 1.5 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KXS20289.1 - 9.1e-19 67.9 0.0 2.5e-18 66.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXS20289.1 - 1.1e-07 32.0 0.0 9.5e-07 29.0 0.0 2.5 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 KXS20289.1 - 0.00018 20.8 0.0 0.0012 18.1 0.0 2.1 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 NAPRTase_C PF17956.1 KXS20289.1 - 0.13 12.7 0.2 0.36 11.3 0.2 1.7 1 0 0 1 1 1 0 Nicotinate phosphoribosyltransferase C-terminal domain AMP-binding PF00501.28 KXS20290.1 - 3.5e-57 193.9 0.0 5.2e-57 193.3 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXS20290.1 - 5.4e-09 36.9 0.3 9.8e-09 36.1 0.3 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PTase_Orf2 PF11468.8 KXS20290.1 - 0.17 11.2 0.0 8.6 5.7 0.0 2.2 2 0 0 2 2 2 0 Aromatic prenyltransferase Orf2 DUF2045 PF09741.9 KXS20291.1 - 4.7e-35 121.1 0.0 2.2e-34 118.9 0.0 2.0 1 1 1 2 2 2 1 Uncharacterized conserved protein (DUF2045) ARPC4 PF05856.12 KXS20292.1 - 6.5e-80 266.6 4.0 7.3e-80 266.4 4.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) Tim44 PF04280.15 KXS20293.1 - 1.1e-14 54.8 0.0 1.6e-14 54.2 0.0 1.2 1 0 0 1 1 1 1 Tim44-like domain MBA1 PF07961.11 KXS20293.1 - 0.066 12.3 0.0 0.16 11.0 0.0 1.6 1 1 0 1 1 1 0 MBA1-like protein Antimicrobial_7 PF08102.11 KXS20293.1 - 0.19 12.0 0.7 0.41 10.9 0.7 1.4 1 0 0 1 1 1 0 Scorpion antimicrobial peptide BRE1 PF08647.11 KXS20295.1 - 3.1e-08 33.6 12.1 3.1e-08 33.6 12.1 8.8 6 2 4 10 10 10 1 BRE1 E3 ubiquitin ligase zf-C3HC4 PF00097.25 KXS20295.1 - 1.1e-07 31.7 12.2 2.2e-07 30.6 12.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KXS20295.1 - 4.1e-07 29.8 8.6 7.9e-07 28.8 8.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXS20295.1 - 2.9e-06 27.0 12.1 6e-06 26.0 12.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXS20295.1 - 2.2e-05 24.4 7.9 4.1e-05 23.5 7.9 1.5 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KXS20295.1 - 0.00015 21.5 7.5 0.00028 20.7 7.5 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KXS20295.1 - 0.00022 21.5 10.1 0.00042 20.6 10.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KXS20295.1 - 0.00032 20.6 11.4 0.00062 19.7 11.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KXS20295.1 - 0.0016 18.6 8.7 0.003 17.7 8.7 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 KXS20295.1 - 0.0077 16.1 4.3 0.015 15.1 4.3 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 KXS20295.1 - 0.034 14.4 8.6 0.074 13.4 8.6 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain Ribosomal_L37e PF01907.19 KXS20295.1 - 0.035 14.3 3.0 0.086 13.0 3.0 1.6 1 0 0 1 1 1 0 Ribosomal protein L37e DUF1272 PF06906.11 KXS20295.1 - 0.13 12.4 4.5 0.31 11.2 4.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) ATG16 PF08614.11 KXS20295.1 - 0.2 11.9 104.8 0.32 11.2 18.1 7.1 2 2 4 6 6 6 0 Autophagy protein 16 (ATG16) zf-RING_4 PF14570.6 KXS20295.1 - 0.27 11.1 5.9 0.55 10.1 5.9 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_5 PF17121.5 KXS20295.1 - 0.54 10.2 7.0 1.5 8.7 6.8 1.8 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-CHY PF05495.12 KXS20295.1 - 0.56 10.7 10.5 1.3 9.6 10.5 1.5 1 0 0 1 1 1 0 CHY zinc finger DZR PF12773.7 KXS20295.1 - 0.82 9.7 9.6 1.6 8.8 9.6 1.4 1 0 0 1 1 1 0 Double zinc ribbon Bin3 PF06859.12 KXS20295.1 - 1.4 9.6 3.6 2.3 8.9 0.9 2.9 2 0 0 2 2 1 0 Bicoid-interacting protein 3 (Bin3) zf-ribbon_3 PF13248.6 KXS20295.1 - 7.4 6.1 5.8 1 8.8 0.7 2.1 2 0 0 2 2 2 0 zinc-ribbon domain Cluap1 PF10234.9 KXS20296.1 - 3.1e-101 338.3 5.5 4e-101 337.9 5.5 1.1 1 0 0 1 1 1 1 Clusterin-associated protein-1 Macoilin PF09726.9 KXS20296.1 - 0.0046 15.6 10.1 0.0063 15.1 10.1 1.2 1 0 0 1 1 1 1 Macoilin family LIF_OSM PF01291.17 KXS20296.1 - 0.0062 16.7 3.3 0.011 15.9 3.3 1.4 1 0 0 1 1 1 1 LIF / OSM family CCDC144C PF14915.6 KXS20296.1 - 0.0063 15.7 15.3 0.014 14.5 15.3 1.5 1 1 0 1 1 1 1 CCDC144C protein coiled-coil region HMMR_N PF15905.5 KXS20296.1 - 0.012 15.1 13.8 0.02 14.4 13.8 1.3 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal CENP-F_leu_zip PF10473.9 KXS20296.1 - 0.016 15.2 9.3 0.016 15.2 9.3 2.3 2 1 1 3 3 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 BAG6 PF12057.8 KXS20296.1 - 0.03 14.0 4.0 0.56 9.9 0.0 2.7 2 0 0 2 2 2 0 BCL2-associated athanogene 6 Fez1 PF06818.15 KXS20296.1 - 0.074 13.5 19.0 0.05 14.1 16.9 1.6 1 1 1 2 2 2 0 Fez1 DUF4407 PF14362.6 KXS20296.1 - 0.12 11.7 7.8 0.2 11.0 7.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CEP63 PF17045.5 KXS20296.1 - 0.13 12.2 20.1 2 8.3 19.4 2.4 1 1 1 2 2 2 0 Centrosomal protein of 63 kDa Spc7 PF08317.11 KXS20296.1 - 0.15 10.9 17.4 0.34 9.8 16.2 2.0 1 1 0 1 1 1 0 Spc7 kinetochore protein Prominin PF05478.11 KXS20296.1 - 0.16 9.9 10.5 0.081 10.9 7.3 1.7 2 0 0 2 2 2 0 Prominin CREPT PF16566.5 KXS20296.1 - 0.17 12.1 16.6 0.63 10.2 1.2 2.7 1 1 2 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour Sec34 PF04136.15 KXS20296.1 - 0.26 11.1 10.3 1.2 9.0 7.4 2.4 2 0 0 2 2 2 0 Sec34-like family T3SSipB PF16535.5 KXS20296.1 - 0.31 11.5 5.6 1.2 9.6 5.6 1.9 1 1 0 1 1 1 0 Type III cell invasion protein SipB IMS PF00817.20 KXS20296.1 - 0.31 11.0 1.4 0.77 9.8 1.4 1.6 1 0 0 1 1 1 0 impB/mucB/samB family HrpB7 PF09486.10 KXS20296.1 - 0.36 11.2 9.5 0.77 10.1 9.5 1.6 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) IFT57 PF10498.9 KXS20296.1 - 0.51 9.2 15.9 1.1 8.2 14.2 2.1 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 NPV_P10 PF05531.12 KXS20296.1 - 0.63 10.5 5.0 2.1 8.9 1.2 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Atg14 PF10186.9 KXS20296.1 - 0.7 8.9 10.8 1 8.4 10.8 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Laminin_II PF06009.12 KXS20296.1 - 0.71 9.9 11.3 0.09 12.8 3.9 2.6 2 1 1 3 3 3 0 Laminin Domain II Exonuc_VII_L PF02601.15 KXS20296.1 - 0.79 9.2 16.4 1.3 8.5 16.3 1.4 1 1 0 1 1 1 0 Exonuclease VII, large subunit LMBR1 PF04791.16 KXS20296.1 - 0.82 8.5 5.6 1 8.2 5.6 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Lebercilin PF15619.6 KXS20296.1 - 0.87 9.2 21.1 0.34 10.6 18.2 1.7 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DUF1664 PF07889.12 KXS20296.1 - 0.93 9.5 8.9 1.3 9.0 3.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) HAUS-augmin3 PF14932.6 KXS20296.1 - 1.6 8.3 20.0 3.5 7.1 4.7 2.2 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 DUF4795 PF16043.5 KXS20296.1 - 1.6 8.3 14.6 11 5.5 14.1 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) Tweety PF04906.13 KXS20296.1 - 1.8 7.2 10.7 0.42 9.2 2.1 2.3 1 1 1 2 2 2 0 Tweety HIP1_clath_bdg PF16515.5 KXS20296.1 - 2.1 9.0 22.7 0.16 12.6 6.9 3.1 2 1 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Tho2 PF11262.8 KXS20296.1 - 2.7 7.1 10.4 0.64 9.2 6.5 1.7 1 1 1 2 2 2 0 Transcription factor/nuclear export subunit protein 2 TMPIT PF07851.13 KXS20296.1 - 3.7 6.7 14.1 43 3.2 13.8 2.2 1 1 0 1 1 1 0 TMPIT-like protein DUF5344 PF17279.2 KXS20296.1 - 4.3 8.0 12.2 25 5.6 1.3 3.5 1 1 2 3 3 3 0 Family of unknown function (DUF5344) EzrA PF06160.12 KXS20296.1 - 4.3 5.4 18.8 0.59 8.2 4.7 2.2 1 1 0 2 2 2 0 Septation ring formation regulator, EzrA FapA PF03961.13 KXS20296.1 - 6.2 5.3 11.5 21 3.6 11.3 1.8 1 1 1 2 2 2 0 Flagellar Assembly Protein A PI3K_P85_iSH2 PF16454.5 KXS20296.1 - 6.7 6.3 24.8 1.4 8.5 5.4 2.4 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain USP8_interact PF08941.10 KXS20296.1 - 7.2 6.4 10.2 0.85 9.4 4.3 2.2 1 1 1 2 2 2 0 USP8 interacting Methyltr_RsmB-F PF01189.17 KXS20297.1 - 9.1e-23 80.9 0.1 1.7e-18 67.0 0.1 3.2 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F CDC45 PF02724.14 KXS20297.1 - 0.46 8.7 2.9 0.72 8.1 2.9 1.2 1 0 0 1 1 1 0 CDC45-like protein G_path_suppress PF15991.5 KXS20297.1 - 2.5 8.2 6.5 1.3 9.1 0.3 2.2 2 0 0 2 2 2 0 G-protein pathway suppressor Ras PF00071.22 KXS20298.1 - 4.5e-16 58.9 0.0 5.9e-16 58.5 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXS20298.1 - 0.0029 17.8 0.0 0.0091 16.2 0.0 1.8 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_18 PF13238.6 KXS20298.1 - 0.21 12.1 0.4 4.3 7.9 0.0 2.6 2 1 0 2 2 2 0 AAA domain NDK PF00334.19 KXS20299.1 - 1.8e-31 109.0 0.0 3.4e-25 88.6 0.0 2.3 2 0 0 2 2 2 2 Nucleoside diphosphate kinase Pkinase PF00069.25 KXS20300.1 - 2.3e-61 207.5 0.0 2.7e-61 207.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS20300.1 - 4.9e-38 130.9 0.0 6.1e-38 130.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXS20300.1 - 9.2e-06 25.2 0.0 2.4e-05 23.8 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 KXS20300.1 - 0.0011 18.0 0.0 0.0016 17.5 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KXS20300.1 - 0.0042 17.0 0.0 0.021 14.8 0.0 1.9 2 1 1 3 3 3 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXS20300.1 - 0.024 13.4 0.0 0.027 13.3 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Seadorna_VP7 PF07387.11 KXS20300.1 - 0.046 12.8 0.0 0.096 11.7 0.0 1.5 2 0 0 2 2 2 0 Seadornavirus VP7 F-box-like PF12937.7 KXS20301.1 - 7.7e-13 48.1 0.0 1.4e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXS20301.1 - 8.6e-10 38.3 0.1 1.4e-09 37.6 0.1 1.4 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KXS20301.1 - 0.01 15.7 0.2 0.02 14.8 0.2 1.6 1 1 0 1 1 1 0 F-box UIM PF02809.20 KXS20302.1 - 0.014 15.2 3.5 0.014 15.2 3.5 3.7 4 0 0 4 4 4 0 Ubiquitin interaction motif Amino_oxidase PF01593.24 KXS20303.1 - 6.3e-70 236.7 0.0 8.5e-70 236.3 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KXS20303.1 - 1.5e-14 54.0 0.4 3.5e-14 52.8 0.4 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXS20303.1 - 6.9e-06 25.9 0.6 1.5e-05 24.8 0.6 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KXS20303.1 - 7.1e-05 23.3 0.1 0.0002 21.9 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXS20303.1 - 7.4e-05 22.1 0.0 0.00013 21.3 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KXS20303.1 - 0.00012 21.5 0.5 0.0002 20.9 0.5 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 KXS20303.1 - 0.00019 20.6 0.1 0.00037 19.7 0.1 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KXS20303.1 - 0.00064 19.1 0.1 0.0012 18.2 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXS20303.1 - 0.0016 17.6 0.1 0.0024 17.0 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 KXS20303.1 - 0.014 14.7 0.1 0.026 13.8 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 KXS20303.1 - 0.023 13.9 0.1 0.043 13.1 0.1 1.3 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 KXS20303.1 - 0.024 13.3 0.1 0.042 12.5 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein Septin PF00735.18 KXS20304.1 - 7.3e-107 356.8 0.0 9.5e-107 356.5 0.0 1.1 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KXS20304.1 - 9.3e-07 28.9 0.0 1.7e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 KXS20304.1 - 0.00034 20.7 0.2 0.15 12.1 0.0 2.5 1 1 1 2 2 2 2 Dynamin family RsgA_GTPase PF03193.16 KXS20304.1 - 0.0017 18.3 3.9 0.0044 16.9 0.7 2.9 3 1 0 3 3 3 1 RsgA GTPase AIG1 PF04548.16 KXS20304.1 - 0.0027 17.1 0.1 0.0055 16.0 0.1 1.5 1 0 0 1 1 1 1 AIG1 family AAA_24 PF13479.6 KXS20304.1 - 0.0067 16.2 0.0 0.014 15.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain Roc PF08477.13 KXS20304.1 - 0.0076 16.5 0.0 0.038 14.2 0.0 1.9 1 1 1 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase FtsK_SpoIIIE PF01580.18 KXS20304.1 - 0.014 14.8 0.1 0.025 13.9 0.1 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF87 PF01935.17 KXS20304.1 - 0.017 15.2 0.4 0.26 11.3 0.0 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain GTP_EFTU PF00009.27 KXS20304.1 - 0.02 14.4 0.0 1.5 8.3 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 KXS20304.1 - 0.028 14.9 0.5 0.085 13.4 0.0 2.0 2 1 0 2 2 2 0 ABC transporter RNA_helicase PF00910.22 KXS20304.1 - 0.051 14.0 0.0 0.097 13.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase tRNA_synthFbeta PF17759.1 KXS20304.1 - 0.059 12.8 0.0 0.09 12.2 0.0 1.2 1 0 0 1 1 1 0 Phenylalanyl tRNA synthetase beta chain CLM domain Ras PF00071.22 KXS20304.1 - 0.067 12.8 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Ras family IIGP PF05049.13 KXS20304.1 - 0.072 12.1 0.1 0.14 11.2 0.1 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_29 PF13555.6 KXS20304.1 - 0.081 12.7 0.1 0.17 11.7 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.6 KXS20304.1 - 0.095 12.9 0.2 0.25 11.5 0.0 1.8 2 0 0 2 2 1 0 AAA domain DLP_helical PF18709.1 KXS20304.1 - 0.12 11.6 0.6 0.17 11.0 0.6 1.2 1 0 0 1 1 1 0 Dynamin-like helical domain AAA_23 PF13476.6 KXS20304.1 - 1.3 9.5 6.9 15 6.0 6.9 2.3 1 1 0 1 1 1 0 AAA domain SecY PF00344.20 KXS20305.1 - 1.5e-71 241.2 10.2 2.1e-71 240.7 10.2 1.2 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 KXS20305.1 - 4.8e-19 67.9 0.5 1.1e-18 66.7 0.5 1.7 1 0 0 1 1 1 1 Plug domain of Sec61p TMEM208_SND2 PF05620.11 KXS20305.1 - 0.21 11.3 1.1 1.7 8.4 0.0 2.8 3 0 0 3 3 3 0 SRP-independent targeting protein 2/TMEM208 RhlB PF12300.8 KXS20306.1 - 0.0096 16.1 2.3 0.015 15.4 2.3 1.3 1 0 0 1 1 1 1 ATP-dependent RNA helicase RhlB RasGEF PF00617.19 KXS20307.1 - 2e-48 165.0 0.1 3.3e-48 164.2 0.1 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KXS20307.1 - 8.9e-17 61.3 0.1 4.6e-16 59.0 0.0 2.2 2 0 0 2 2 2 1 RasGEF N-terminal motif 3HCDH_N PF02737.18 KXS20308.1 - 8e-56 188.8 0.8 1e-55 188.4 0.8 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KXS20308.1 - 3.5e-34 117.3 0.0 7.2e-34 116.3 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Chorismate_bind PF00425.18 KXS20309.1 - 2e-80 270.1 0.0 2.8e-80 269.6 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme Aminotran_4 PF01063.19 KXS20309.1 - 2.4e-32 112.6 0.0 4.1e-32 111.8 0.0 1.3 1 0 0 1 1 1 1 Amino-transferase class IV 2OG-Fe_Oxy_2 PF10014.9 KXS20310.1 - 0.044 13.6 0.0 0.073 12.9 0.0 1.3 1 0 0 1 1 1 0 2OG-Fe dioxygenase 2OG-FeII_Oxy_3 PF13640.6 KXS20310.1 - 0.072 14.0 0.0 0.14 13.0 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily NAD_binding_11 PF14833.6 KXS20313.1 - 1.3e-26 93.2 0.0 2.3e-26 92.4 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.15 KXS20313.1 - 4.3e-26 92.0 0.0 7.4e-26 91.2 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase MarR_2 PF12802.7 KXS20313.1 - 0.05 13.5 0.1 0.6 10.0 0.0 2.4 2 1 0 2 2 2 0 MarR family DUF1298 PF06974.13 KXS20313.1 - 0.067 13.1 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1298) GST_C_2 PF13410.6 KXS20313.1 - 0.095 12.7 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain MBOAT PF03062.19 KXS20314.1 - 4e-35 121.8 7.2 5.9e-35 121.2 7.2 1.3 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family PDEase_I PF00233.19 KXS20315.1 - 1.1e-82 277.4 0.0 2.3e-82 276.3 0.0 1.5 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase DUF3301 PF11743.8 KXS20315.1 - 0.03 14.0 0.1 0.056 13.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3301) SGTA_dimer PF16546.5 KXS20315.1 - 0.036 13.8 0.4 0.16 11.7 0.3 2.0 2 0 0 2 2 2 0 Homodimerisation domain of SGTA PDEase_I_N PF08499.12 KXS20315.1 - 0.064 13.1 0.1 0.19 11.6 0.1 1.8 1 0 0 1 1 1 0 3'5'-cyclic nucleotide phosphodiesterase N-terminal SNAD3 PF18749.1 KXS20315.1 - 0.064 12.4 0.1 0.097 11.8 0.1 1.2 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 3 zf-C4H2 PF10146.9 KXS20315.1 - 0.13 12.6 4.6 6 7.1 0.2 2.3 2 0 0 2 2 2 0 Zinc finger-containing protein Pribosyltran PF00156.27 KXS20316.1 - 2.5e-14 53.1 0.3 3.2e-14 52.7 0.3 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KXS20316.1 - 0.042 13.3 0.0 0.066 12.6 0.0 1.3 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase PRTase_2 PF15609.6 KXS20316.1 - 0.13 11.7 0.0 0.19 11.2 0.0 1.1 1 0 0 1 1 1 0 Phosphoribosyl transferase F-box-like PF12937.7 KXS20318.1 - 0.00022 21.0 0.1 0.00062 19.6 0.1 1.8 1 0 0 1 1 1 1 F-box-like MscS_porin PF12795.7 KXS20319.1 - 0.0016 18.0 11.8 0.0016 18.0 11.8 4.3 1 1 3 4 4 4 1 Mechanosensitive ion channel porin domain MCC-bdg_PDZ PF10506.9 KXS20319.1 - 0.015 15.3 15.0 1.3 9.1 1.5 4.6 3 1 0 3 3 3 0 PDZ domain of MCC-2 bdg protein for Usher syndrome HALZ PF02183.18 KXS20319.1 - 0.67 10.2 0.0 0.67 10.2 0.0 4.5 4 0 0 4 4 4 0 Homeobox associated leucine zipper RE_TdeIII PF09520.10 KXS20319.1 - 7.3 6.2 12.1 1.3 8.6 2.7 2.6 3 0 0 3 3 3 0 Type II restriction endonuclease, TdeIII RCC1 PF00415.18 KXS20320.1 - 8.2e-06 26.3 0.4 0.055 14.1 0.0 3.6 3 1 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat Cation_ATPase_C PF00689.21 KXS20321.1 - 2e-05 24.4 1.7 2e-05 24.4 1.7 2.2 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KXS20321.1 - 0.0044 17.3 0.0 0.34 11.2 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KXS20321.1 - 0.0046 16.5 0.0 0.0046 16.5 0.0 3.1 3 0 0 3 3 3 1 E1-E2 ATPase DUF4140 PF13600.6 KXS20322.1 - 1e-07 32.3 0.2 1.2e-07 32.0 0.2 1.2 1 0 0 1 1 1 1 N-terminal domain of unknown function (DUF4140) DUF5614 PF18474.1 KXS20322.1 - 0.045 13.1 0.0 0.046 13.0 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5614) DUF4982 PF16355.5 KXS20322.1 - 0.094 12.7 0.1 0.11 12.4 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4982) DUF4139 PF13598.6 KXS20323.1 - 2.6e-56 190.7 0.1 1.5e-54 184.9 0.1 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF4139) Syntaxin-6_N PF09177.11 KXS20323.1 - 0.023 15.3 0.2 0.07 13.7 0.2 1.8 1 0 0 1 1 1 0 Syntaxin 6, N-terminal COG2 PF06148.11 KXS20323.1 - 0.028 14.5 1.0 2.9 8.0 0.5 2.3 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 EzrA PF06160.12 KXS20323.1 - 0.12 10.6 0.7 5.1 5.1 0.1 2.0 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA SGL PF08450.12 KXS20324.1 - 4.6e-30 105.0 2.8 7e-29 101.1 2.9 2.0 1 1 1 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 KXS20324.1 - 0.0013 18.7 3.6 0.93 9.7 0.1 4.4 5 0 0 5 5 5 1 NHL repeat Str_synth PF03088.16 KXS20324.1 - 0.0037 17.3 0.0 0.012 15.7 0.0 1.8 2 0 0 2 2 2 1 Strictosidine synthase Lactonase PF10282.9 KXS20324.1 - 0.044 13.1 0.0 0.1 11.8 0.0 1.6 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller ADK PF00406.22 KXS20325.1 - 1.2e-20 74.2 0.0 9.9e-14 51.7 0.0 2.2 2 0 0 2 2 2 2 Adenylate kinase AAA_17 PF13207.6 KXS20325.1 - 1.5e-10 41.6 0.0 7e-05 23.3 0.0 2.8 3 0 0 3 3 3 2 AAA domain DUF5586 PF17824.1 KXS20325.1 - 0.14 11.3 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5586) Serinc PF03348.15 KXS20326.1 - 8.7e-132 440.1 13.7 9.8e-132 439.9 13.7 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) zf-met PF12874.7 KXS20328.1 - 4.1e-06 27.0 1.1 1e-05 25.7 1.1 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KXS20328.1 - 0.00027 21.1 1.1 0.00049 20.3 0.8 1.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding COG2 PF06148.11 KXS20328.1 - 0.15 12.2 1.1 0.23 11.5 1.1 1.3 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 AKAP95 PF04988.12 KXS20328.1 - 0.16 12.2 0.0 0.31 11.3 0.0 1.4 1 0 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) Seryl_tRNA_N PF02403.22 KXS20328.1 - 1.8 8.8 6.5 0.34 11.2 1.5 2.4 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF4106 PF13388.6 KXS20329.1 - 2.5 7.2 13.8 2.6 7.2 13.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Molybdopterin PF00384.22 KXS20331.1 - 4.5e-66 223.6 0.0 4.2e-65 220.4 0.0 2.0 1 1 0 1 1 1 1 Molybdopterin oxidoreductase NADH-G_4Fe-4S_3 PF10588.9 KXS20331.1 - 4.6e-17 61.3 0.2 4.6e-17 61.3 0.2 1.9 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region NADH_dhqG_C PF09326.11 KXS20331.1 - 2.7e-16 60.0 0.2 7.1e-16 58.6 0.2 1.8 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit G, C-terminal Fer2_4 PF13510.6 KXS20331.1 - 1.8e-09 37.5 0.4 4.2e-09 36.3 0.4 1.7 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.22 KXS20331.1 - 0.01 15.5 0.1 0.062 13.0 0.0 2.1 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Fer2 PF00111.27 KXS20331.1 - 0.014 15.3 0.5 0.014 15.3 0.5 2.0 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain Fer4 PF00037.27 KXS20331.1 - 0.052 13.4 1.0 3.1 7.8 0.3 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_4 PF12800.7 KXS20331.1 - 6.7 7.5 6.5 1.3 9.7 1.6 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain TLD PF07534.16 KXS20332.1 - 5.9e-31 107.6 0.7 1.1e-30 106.7 0.7 1.4 1 0 0 1 1 1 1 TLD Cofilin_ADF PF00241.20 KXS20333.1 - 1.6e-21 76.3 0.0 1.9e-21 76.1 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Tub PF01167.18 KXS20334.1 - 2.9e-60 204.0 0.0 3.4e-60 203.8 0.0 1.0 1 0 0 1 1 1 1 Tub family Serglycin PF04360.12 KXS20334.1 - 7e-05 22.8 0.1 0.00012 22.0 0.1 1.3 1 0 0 1 1 1 1 Serglycin AAA_10 PF12846.7 KXS20334.1 - 0.21 10.5 0.0 0.35 9.7 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain 2-oxoacid_dh PF00198.23 KXS20335.1 - 2.9e-73 246.2 0.2 4.5e-73 245.5 0.2 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KXS20335.1 - 3.2e-38 129.4 3.5 6.2e-19 67.6 0.7 3.0 2 0 0 2 2 2 2 Biotin-requiring enzyme HAD PF12710.7 KXS20335.1 - 2.1e-21 77.2 0.1 4e-21 76.3 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KXS20335.1 - 7.2e-16 59.1 2.8 3.1e-15 57.0 2.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase E3_binding PF02817.17 KXS20335.1 - 2.2e-15 56.7 0.9 6e-15 55.3 0.9 1.9 1 0 0 1 1 1 1 e3 binding domain Hydrolase_3 PF08282.12 KXS20335.1 - 5.5e-08 32.8 0.1 1.8e-07 31.2 0.0 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase MMM1 PF10296.9 KXS20335.1 - 0.00054 19.1 0.0 0.024 13.7 0.0 2.2 2 0 0 2 2 2 1 Maintenance of mitochondrial morphology protein 1 Biotin_lipoyl_2 PF13533.6 KXS20335.1 - 0.00085 19.1 0.0 0.42 10.5 0.0 2.7 2 0 0 2 2 2 2 Biotin-lipoyl like DnaB_bind PF10410.9 KXS20335.1 - 0.0018 18.4 0.4 0.27 11.4 0.1 2.8 2 0 0 2 2 2 1 DnaB-helicase binding domain of primase Put_Phosphatase PF06888.12 KXS20335.1 - 0.021 14.2 0.0 3.4 7.0 0.0 2.2 2 0 0 2 2 2 0 Putative Phosphatase ACT_6 PF13740.6 KXS20335.1 - 0.05 13.6 0.1 0.15 12.1 0.1 1.8 1 0 0 1 1 1 0 ACT domain HAD PF12710.7 KXS20336.1 - 1.1e-22 81.4 0.1 1.8e-22 80.7 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KXS20336.1 - 8.5e-17 62.1 2.0 1.4e-16 61.5 2.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KXS20336.1 - 6.8e-10 39.1 0.1 5.6e-09 36.1 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 KXS20336.1 - 0.00031 20.2 0.0 0.31 10.4 0.0 2.2 2 0 0 2 2 2 2 Putative Phosphatase DUF705 PF05152.12 KXS20336.1 - 0.035 13.6 0.1 0.052 13.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF705) PSCyt2 PF07583.11 KXS20337.1 - 0.00013 21.9 0.1 0.00026 21.0 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1549) Glycos_transf_2 PF00535.26 KXS20338.1 - 7.4e-25 87.7 0.0 2.1e-24 86.3 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KXS20338.1 - 6.2e-06 26.3 0.1 0.00076 19.4 0.1 2.2 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 KXS20338.1 - 0.0096 16.4 0.0 0.073 13.6 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 KXS20338.1 - 0.024 14.1 0.1 0.05 13.1 0.0 1.5 2 0 0 2 2 2 0 Glycosyltransferase like family 2 Ribosomal_S4e PF00900.20 KXS20339.1 - 1.6e-38 130.4 2.6 1.3e-37 127.6 0.5 2.3 2 0 0 2 2 2 1 Ribosomal family S4e 40S_S4_C PF16121.5 KXS20339.1 - 4.2e-23 80.7 0.2 7.2e-23 80.0 0.2 1.4 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 KXS20339.1 - 1.5e-21 76.2 8.2 2.7e-21 75.4 8.2 1.4 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.25 KXS20339.1 - 2.2e-10 40.1 0.1 5.1e-10 38.9 0.1 1.7 1 0 0 1 1 1 1 S4 domain KOW PF00467.29 KXS20339.1 - 3.2e-06 26.9 0.7 3.2e-06 26.9 0.7 3.1 3 0 0 3 3 3 1 KOW motif DUF3912 PF13051.6 KXS20339.1 - 0.031 14.5 1.1 2.1 8.7 0.4 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3912) Sipho_tail PF05709.11 KXS20339.1 - 0.092 12.1 0.1 0.19 11.1 0.1 1.6 1 1 0 1 1 1 0 Phage tail protein Kelch_4 PF13418.6 KXS20339.1 - 0.53 10.3 1.8 72 3.5 0.2 3.3 3 0 0 3 3 3 0 Galactose oxidase, central domain DUF3712 PF12505.8 KXS20341.1 - 5.2e-40 136.6 23.3 3.4e-23 82.3 0.1 5.5 5 0 0 5 5 5 3 Protein of unknown function (DUF3712) LEA_2 PF03168.13 KXS20341.1 - 1.3e-08 35.3 12.7 0.36 11.4 0.3 5.3 5 1 0 5 5 5 4 Late embryogenesis abundant protein DUF4097 PF13349.6 KXS20341.1 - 0.07 12.5 1.9 0.22 10.8 1.1 2.2 2 1 1 3 3 3 0 Putative adhesin CytB6-F_Fe-S PF08802.10 KXS20341.1 - 0.071 13.1 2.7 0.1 12.7 0.5 2.6 2 0 0 2 2 2 0 Cytochrome B6-F complex Fe-S subunit DUF2085 PF09858.9 KXS20341.1 - 0.33 11.5 1.1 0.99 9.9 0.2 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2085) RhoGAP PF00620.27 KXS20343.1 - 1.4e-30 106.1 0.0 2.2e-30 105.5 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain CRAL_TRIO_2 PF13716.6 KXS20343.1 - 1.1e-29 103.3 0.0 2.2e-29 102.4 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.20 KXS20343.1 - 1.1e-05 25.2 0.2 0.00011 22.0 0.2 2.1 1 1 0 1 1 1 1 CRAL/TRIO domain Chitin_bind_1 PF00187.19 KXS20345.1 - 2.8e-05 24.5 14.1 2.8e-05 24.5 14.1 4.5 4 2 0 4 4 4 1 Chitin recognition protein GMC_oxred_N PF00732.19 KXS20346.1 - 7.6e-77 258.6 0.0 1.2e-76 258.0 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXS20346.1 - 1.8e-42 145.2 0.0 3.3e-42 144.4 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KXS20346.1 - 2.7e-05 23.4 0.3 6e-05 22.3 0.0 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KXS20346.1 - 0.00023 21.3 0.1 0.00079 19.6 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KXS20346.1 - 0.0011 18.2 0.1 0.0044 16.3 0.0 1.9 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 KXS20346.1 - 0.008 15.8 0.0 0.024 14.2 0.0 1.8 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXS20346.1 - 0.016 14.4 0.1 0.053 12.7 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXS20346.1 - 0.033 13.3 0.3 0.1 11.7 0.0 1.9 2 0 0 2 2 2 0 FAD binding domain DUF1325 PF07039.11 KXS20349.1 - 0.00012 22.2 0.0 0.00012 22.2 0.0 2.9 4 0 0 4 4 4 1 SGF29 tudor-like domain UvrD-helicase PF00580.21 KXS20350.1 - 2.9e-10 40.2 0.0 6.5e-09 35.7 0.0 2.6 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 KXS20350.1 - 5.5e-10 39.7 0.0 3.5e-09 37.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain UvrD_C PF13361.6 KXS20350.1 - 1.5e-06 27.9 0.0 2.4e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 KXS20350.1 - 3.5e-06 26.9 0.0 6.8e-05 22.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain UvrD_C_2 PF13538.6 KXS20350.1 - 4.7e-06 26.3 0.0 0.035 14.0 0.0 2.6 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain AAA_16 PF13191.6 KXS20350.1 - 0.017 15.5 0.1 0.05 14.0 0.1 1.8 1 0 0 1 1 1 0 AAA ATPase domain Viral_helicase1 PF01443.18 KXS20350.1 - 0.053 13.2 0.0 17 5.1 0.0 3.1 4 0 0 4 4 4 0 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 KXS20350.1 - 0.16 11.2 0.0 0.38 9.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Herpes_ori_bp PF02399.15 KXS20350.1 - 0.16 10.0 0.0 0.23 9.4 0.0 1.1 1 0 0 1 1 1 0 Origin of replication binding protein HhH-GPD PF00730.25 KXS20352.1 - 7e-15 55.4 0.0 1.1e-14 54.8 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 KXS20352.1 - 1.2e-06 28.1 0.0 3.7e-06 26.5 0.0 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.9 KXS20352.1 - 0.024 15.0 2.7 0.047 14.0 2.7 1.5 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III UQ_con PF00179.26 KXS20353.1 - 5.6e-39 133.0 0.0 8e-39 132.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Lon_C PF05362.13 KXS20354.1 - 2.1e-84 282.2 1.0 2.1e-84 282.2 1.0 1.8 2 0 0 2 2 2 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.29 KXS20354.1 - 1.9e-21 76.9 0.0 6.7e-21 75.1 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) LON_substr_bdg PF02190.16 KXS20354.1 - 2.9e-08 33.8 3.8 7e-08 32.6 0.2 2.2 2 0 0 2 2 2 1 ATP-dependent protease La (LON) substrate-binding domain ChlI PF13541.6 KXS20354.1 - 7.1e-08 32.3 0.1 1.4e-07 31.4 0.1 1.5 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_5 PF07728.14 KXS20354.1 - 1.4e-07 31.6 0.0 2.7e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KXS20354.1 - 1.4e-05 25.3 0.0 0.00037 20.6 0.0 2.6 2 1 1 3 3 3 1 AAA domain (Cdc48 subfamily) AAA_PrkA PF08298.11 KXS20354.1 - 5.3e-05 22.3 0.0 0.0001 21.3 0.0 1.4 1 0 0 1 1 1 1 PrkA AAA domain RuvB_N PF05496.12 KXS20354.1 - 0.0002 21.1 0.0 0.0015 18.3 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KXS20354.1 - 0.00044 20.5 0.0 0.014 15.6 0.0 2.6 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 KXS20354.1 - 0.00053 19.9 0.0 0.0016 18.4 0.0 1.7 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 KXS20354.1 - 0.00088 19.7 1.3 0.0045 17.4 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_3 PF07726.11 KXS20354.1 - 0.0064 16.3 0.0 0.019 14.8 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 KXS20354.1 - 0.0099 15.6 0.0 0.13 12.0 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_23 PF13476.6 KXS20354.1 - 0.028 14.9 9.0 1.5 9.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KXS20354.1 - 0.042 14.2 0.0 0.092 13.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.6 KXS20354.1 - 0.044 14.3 0.8 0.12 12.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain MCM PF00493.23 KXS20354.1 - 0.054 12.6 0.1 0.17 11.0 0.0 1.9 2 0 0 2 2 2 0 MCM P-loop domain AAA_33 PF13671.6 KXS20354.1 - 0.069 13.3 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KXS20354.1 - 0.16 12.5 0.7 1.6 9.2 0.0 2.4 2 0 0 2 2 2 0 ABC transporter LTXXQ PF07813.12 KXS20354.1 - 0.25 12.1 4.5 62 4.4 0.0 3.1 2 1 0 3 3 3 0 LTXXQ motif family protein PX PF00787.24 KXS20355.1 - 6.5e-22 77.6 0.2 2.2e-21 76.0 0.1 1.9 2 0 0 2 2 2 1 PX domain BAR PF03114.18 KXS20355.1 - 1.6e-05 24.7 1.6 3.5e-05 23.6 0.2 2.1 2 0 0 2 2 2 1 BAR domain BAR_3_WASP_bdg PF10456.9 KXS20355.1 - 4.1e-05 23.2 0.2 0.4 10.1 0.0 2.9 3 0 0 3 3 3 2 WASP-binding domain of Sorting nexin protein Vps5 PF09325.10 KXS20355.1 - 0.47 10.0 6.2 1.7 8.2 2.1 2.3 2 0 0 2 2 2 0 Vps5 C terminal like PRIMA1 PF16101.5 KXS20355.1 - 2.6 8.1 9.4 0.16 12.0 2.7 2.2 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 DAGK_cat PF00781.24 KXS20356.1 - 0.017 14.7 0.0 0.023 14.3 0.0 1.2 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain FixP_N PF14715.6 KXS20359.1 - 0.054 13.2 0.1 0.17 11.7 0.1 1.8 1 0 0 1 1 1 0 N-terminal domain of cytochrome oxidase-cbb3, FixP PhoR PF11808.8 KXS20359.1 - 3.3 8.2 10.0 0.72 10.3 0.8 3.0 3 1 1 4 4 4 0 Phosphate regulon sensor protein PhoR MSP1_C PF07462.11 KXS20359.1 - 7.5 5.1 5.0 9.8 4.7 5.0 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Yos1 PF08571.10 KXS20360.1 - 6.3e-31 106.5 0.8 7e-31 106.3 0.8 1.0 1 0 0 1 1 1 1 Yos1-like Synaptobrevin PF00957.21 KXS20361.1 - 4.2e-33 113.0 7.2 4.7e-33 112.8 7.2 1.0 1 0 0 1 1 1 1 Synaptobrevin DUF2937 PF11157.8 KXS20361.1 - 0.00044 20.0 0.7 0.00049 19.8 0.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2937) Peptidase_M48_N PF16491.5 KXS20361.1 - 0.01 15.8 0.5 0.014 15.3 0.5 1.2 1 0 0 1 1 1 0 CAAX prenyl protease N-terminal, five membrane helices Pex24p PF06398.11 KXS20361.1 - 0.011 14.7 0.0 0.012 14.6 0.0 1.0 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin RIFIN PF02009.16 KXS20361.1 - 0.013 15.4 2.0 0.015 15.2 2.0 1.1 1 0 0 1 1 1 0 Rifin MCU PF04678.13 KXS20361.1 - 0.017 15.2 1.2 0.019 15.0 1.2 1.0 1 0 0 1 1 1 0 Mitochondrial calcium uniporter Fzo_mitofusin PF04799.13 KXS20361.1 - 0.027 14.0 1.5 0.039 13.5 1.5 1.3 1 0 0 1 1 1 0 fzo-like conserved region ODV-E18 PF10717.9 KXS20361.1 - 0.076 12.9 1.1 0.1 12.5 1.1 1.3 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Tweety PF04906.13 KXS20361.1 - 0.097 11.3 1.8 0.11 11.1 1.8 1.1 1 0 0 1 1 1 0 Tweety ASFV_J13L PF05568.11 KXS20361.1 - 0.72 9.6 3.2 0.96 9.2 3.2 1.2 1 0 0 1 1 1 0 African swine fever virus J13L protein LRRC37AB_C PF14914.6 KXS20361.1 - 2.2 8.2 7.3 5.5 6.9 7.3 1.7 1 1 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain zf_CCCH_4 PF18345.1 KXS20362.1 - 5.3e-10 39.0 22.6 2.1e-05 24.4 9.2 2.3 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 KXS20362.1 - 9.9e-10 38.0 13.6 4.3e-05 23.2 0.8 2.3 2 0 0 2 2 2 2 CCCH-type zinc finger Torus PF16131.5 KXS20362.1 - 1.2e-08 35.7 3.4 0.00032 21.4 0.1 2.2 2 0 0 2 2 2 2 Torus domain zf-CCCH PF00642.24 KXS20362.1 - 7.6e-08 32.1 15.9 0.00021 21.1 0.7 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 KXS20362.1 - 0.00059 20.2 8.3 0.0068 16.8 0.3 2.4 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 KXS20362.1 - 0.037 14.2 5.6 0.92 9.7 1.5 2.2 2 0 0 2 2 2 0 Zinc-finger containing family Aldolase_II PF00596.21 KXS20363.1 - 1.5e-34 119.6 0.0 2.2e-34 119.0 0.0 1.3 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Pkinase PF00069.25 KXS20364.1 - 5.2e-10 39.1 0.0 1.3e-09 37.8 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS20364.1 - 3.1e-05 23.4 0.0 4.8e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase TatC PF00902.18 KXS20365.1 - 0.046 13.5 2.7 0.055 13.3 2.7 1.0 1 0 0 1 1 1 0 Sec-independent protein translocase protein (TatC) RGS PF00615.19 KXS20367.1 - 1.1e-06 28.9 0.0 1.4e-06 28.6 0.0 1.0 1 0 0 1 1 1 1 Regulator of G protein signaling domain TRF PF08558.10 KXS20367.1 - 0.19 11.3 0.0 0.23 11.1 0.0 1.0 1 0 0 1 1 1 0 Telomere repeat binding factor (TRF) MFS_1 PF07690.16 KXS20369.1 - 2.1e-20 73.0 18.0 4.5e-20 71.9 18.0 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXS20369.1 - 1.2e-06 27.7 8.6 3.7e-06 26.1 8.6 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 KXS20369.1 - 1.1e-05 24.1 4.3 1.3e-05 23.9 4.3 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 KXS20369.1 - 0.069 12.0 7.4 0.0093 14.9 2.9 1.7 2 0 0 2 2 2 0 MFS_1 like family Adenosine_kin PF04008.14 KXS20371.1 - 2.2e-57 193.2 0.0 7.2e-56 188.3 0.0 2.0 1 1 1 2 2 2 2 Adenosine specific kinase CMD PF02627.20 KXS20372.1 - 1e-16 60.8 0.0 1.6e-16 60.1 0.0 1.3 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family p450 PF00067.22 KXS20373.1 - 7.3e-63 212.9 0.0 3.5e-62 210.6 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 HAD_2 PF13419.6 KXS20374.1 - 3.6e-15 56.5 0.0 1.8e-13 50.9 0.0 2.1 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KXS20374.1 - 1.8e-13 51.3 0.0 8.8e-10 39.2 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KXS20374.1 - 4.6e-05 23.4 0.0 0.00011 22.2 0.0 1.7 2 0 0 2 2 2 1 HAD-hyrolase-like HAD PF12710.7 KXS20374.1 - 0.0027 18.1 0.8 0.05 14.0 0.8 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Tti2 PF10521.9 KXS20374.1 - 0.12 11.9 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 Tti2 family KH_6 PF15985.5 KXS20375.1 - 1.4e-15 57.3 0.0 2.6e-15 56.5 0.0 1.5 1 0 0 1 1 1 1 KH domain Rrp40_N PF18311.1 KXS20375.1 - 1.3e-08 34.6 0.0 2.4e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Exosome complex exonuclease Rrp40 N-terminal domain AMP-binding PF00501.28 KXS20376.1 - 3.2e-93 312.6 0.0 4.2e-93 312.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXS20376.1 - 7.5e-14 52.5 0.0 1.9e-13 51.2 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Asparaginase_2 PF01112.18 KXS20377.1 - 2.5e-38 131.8 12.7 7.5e-20 71.2 1.9 3.8 2 1 1 3 3 3 2 Asparaginase TPR_16 PF13432.6 KXS20379.1 - 0.037 14.7 0.2 2.2 9.0 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TFIIA PF03153.13 KXS20380.1 - 1.5 8.7 4.0 2.4 8.1 4.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Piwi PF02171.17 KXS20382.1 - 3.6e-92 308.8 1.3 6.5e-92 308.0 1.3 1.4 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 KXS20382.1 - 9.2e-19 68.4 0.0 3.5e-18 66.6 0.0 2.1 1 0 0 1 1 1 1 N-terminal domain of argonaute PAZ PF02170.22 KXS20382.1 - 2e-16 60.0 0.0 3.5e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 PAZ domain ArgoL2 PF16488.5 KXS20382.1 - 1.2e-11 44.8 0.0 2.9e-11 43.5 0.0 1.8 1 0 0 1 1 1 1 Argonaute linker 2 domain ArgoL1 PF08699.10 KXS20382.1 - 2.6e-10 39.8 0.1 7e-10 38.4 0.1 1.8 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoMid PF16487.5 KXS20382.1 - 0.025 14.8 0.0 0.062 13.6 0.0 1.7 1 0 0 1 1 1 0 Mid domain of argonaute DUF3811 PF11656.8 KXS20382.1 - 0.025 14.9 1.4 0.058 13.8 1.4 1.5 1 0 0 1 1 1 0 YjbD family (DUF3811) JmjC PF02373.22 KXS20383.1 - 9e-34 116.3 0.1 1.9e-33 115.3 0.1 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase zf-HC5HC2H_2 PF13832.6 KXS20383.1 - 2.8e-12 46.8 1.5 8.4e-10 38.8 0.6 2.6 2 0 0 2 2 2 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 KXS20383.1 - 3.3e-12 46.5 1.9 6.9e-12 45.5 0.7 2.1 2 0 0 2 2 2 1 PHD-like zinc-binding domain JmjN PF02375.17 KXS20383.1 - 9.6e-11 41.5 0.0 2.3e-10 40.2 0.0 1.7 1 0 0 1 1 1 1 jmjN domain zf-ANAPC11 PF12861.7 KXS20383.1 - 0.76 9.9 3.8 1.7 8.8 0.5 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_1 PF14446.6 KXS20383.1 - 1 9.4 4.4 0.47 10.4 0.9 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 TMEM135_C_rich PF15982.5 KXS20384.1 - 0.053 14.1 0.2 0.36 11.4 0.1 2.2 2 0 0 2 2 2 0 N-terminal cysteine-rich region of Transmembrane protein 135 ThiJ_like PF17124.5 KXS20384.1 - 0.078 12.7 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 ThiJ/PfpI family-like LPMO_10 PF03067.15 KXS20385.1 - 6.8e-05 23.6 0.0 0.00014 22.6 0.0 1.4 1 1 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Glyco_hydro_61 PF03443.14 KXS20385.1 - 0.059 13.3 0.2 5.7 6.8 0.0 2.2 1 1 0 2 2 2 0 Glycosyl hydrolase family 61 AAA PF00004.29 KXS20387.1 - 2e-42 144.7 0.0 3e-39 134.5 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KXS20387.1 - 2e-08 33.9 0.0 5.4e-08 32.5 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KXS20387.1 - 6.9e-06 26.5 0.2 0.00087 19.7 0.0 2.9 2 1 0 3 3 2 1 AAA ATPase domain AAA_5 PF07728.14 KXS20387.1 - 4.3e-05 23.5 0.0 0.00024 21.1 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 KXS20387.1 - 0.00026 20.7 0.0 0.0008 19.2 0.0 1.7 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_2 PF07724.14 KXS20387.1 - 0.00029 21.0 0.0 0.00095 19.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KXS20387.1 - 0.00065 20.0 0.1 0.018 15.3 0.1 3.1 2 1 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KXS20387.1 - 0.0025 17.4 0.0 0.059 12.9 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region NACHT PF05729.12 KXS20387.1 - 0.0027 17.7 0.2 0.064 13.2 0.0 2.9 2 1 1 3 3 3 1 NACHT domain RNA_helicase PF00910.22 KXS20387.1 - 0.0033 17.8 0.0 0.019 15.3 0.0 2.2 2 0 0 2 2 2 1 RNA helicase AAA_33 PF13671.6 KXS20387.1 - 0.0034 17.5 0.0 0.014 15.5 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KXS20387.1 - 0.0052 17.3 0.0 0.018 15.6 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KXS20387.1 - 0.0065 16.2 0.2 0.046 13.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 KXS20387.1 - 0.008 15.9 0.0 0.031 14.0 0.0 2.0 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 KXS20387.1 - 0.008 15.6 0.0 0.015 14.6 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 KXS20387.1 - 0.0099 16.1 0.3 0.039 14.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 KXS20387.1 - 0.015 14.5 0.0 0.025 13.8 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain ABC_tran PF00005.27 KXS20387.1 - 0.02 15.4 0.0 0.052 14.1 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_3 PF07726.11 KXS20387.1 - 0.028 14.3 0.0 0.056 13.3 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.6 KXS20387.1 - 0.047 13.8 0.0 0.92 9.6 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain Parvo_NS1 PF01057.17 KXS20387.1 - 0.053 12.6 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_25 PF13481.6 KXS20387.1 - 0.067 12.8 0.1 0.2 11.2 0.1 1.8 1 1 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 KXS20387.1 - 0.1 12.3 0.0 0.49 10.1 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain ResIII PF04851.15 KXS20387.1 - 0.15 12.1 0.0 0.35 10.8 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_11 PF13086.6 KXS20387.1 - 0.25 11.1 0.0 0.25 11.1 0.0 2.8 4 0 0 4 4 4 0 AAA domain Tropomyosin_1 PF12718.7 KXS20388.1 - 1.8e-25 89.8 27.9 2.4e-25 89.4 27.9 1.2 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.20 KXS20388.1 - 8.2e-12 45.0 29.1 2e-06 27.3 13.9 2.8 1 1 1 2 2 2 2 Tropomyosin DHR10 PF18595.1 KXS20388.1 - 5.5e-05 23.2 32.0 0.00043 20.3 6.3 2.3 1 1 0 2 2 2 2 Designed helical repeat protein 10 domain Spc7 PF08317.11 KXS20388.1 - 0.00063 18.7 8.0 0.00063 18.7 8.0 2.5 1 1 1 2 2 2 1 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 KXS20388.1 - 0.0007 19.7 29.2 0.011 15.8 3.1 3.0 1 1 2 3 3 3 2 TPR/MLP1/MLP2-like protein DUF1598 PF07643.11 KXS20388.1 - 0.0017 18.5 0.0 0.0052 17.0 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1598) DUF1192 PF06698.11 KXS20388.1 - 0.0029 17.6 0.4 0.0029 17.6 0.4 3.0 3 0 0 3 3 2 1 Protein of unknown function (DUF1192) CENP-F_leu_zip PF10473.9 KXS20388.1 - 0.0034 17.4 8.8 0.0034 17.4 8.8 2.3 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATG16 PF08614.11 KXS20388.1 - 0.0042 17.3 28.7 0.036 14.3 4.8 2.8 1 1 2 3 3 3 2 Autophagy protein 16 (ATG16) FlxA PF14282.6 KXS20388.1 - 0.0051 16.8 3.9 0.0051 16.8 3.9 2.7 1 1 2 3 3 3 1 FlxA-like protein Fez1 PF06818.15 KXS20388.1 - 0.0054 17.2 24.2 0.28 11.6 14.6 2.0 1 1 1 2 2 2 2 Fez1 HrpB7 PF09486.10 KXS20388.1 - 0.0055 17.1 12.9 0.022 15.2 0.4 2.2 1 1 1 2 2 2 1 Bacterial type III secretion protein (HrpB7) PspA_IM30 PF04012.12 KXS20388.1 - 0.0068 16.0 20.9 0.087 12.4 1.3 2.1 1 1 1 2 2 2 2 PspA/IM30 family TMF_TATA_bd PF12325.8 KXS20388.1 - 0.011 16.0 4.1 0.011 16.0 4.1 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding MscS_porin PF12795.7 KXS20388.1 - 0.023 14.3 21.2 0.052 13.1 20.9 1.7 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain Surfac_D-trimer PF09006.11 KXS20388.1 - 0.037 13.9 0.5 1.4 8.8 0.0 2.6 3 0 0 3 3 2 0 Lung surfactant protein D coiled-coil trimerisation ADIP PF11559.8 KXS20388.1 - 0.059 13.5 27.5 0.062 13.4 1.1 3.1 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding PolyA_pol PF01743.20 KXS20388.1 - 0.079 13.4 0.4 0.079 13.4 0.4 2.0 2 0 0 2 2 2 0 Poly A polymerase head domain DASH_Spc19 PF08287.11 KXS20388.1 - 0.084 12.8 25.2 1.5 8.7 7.4 3.1 1 1 2 3 3 3 0 Spc19 Laminin_II PF06009.12 KXS20388.1 - 0.089 12.8 14.9 0.47 10.5 2.8 2.6 1 1 2 3 3 3 0 Laminin Domain II DLP_helical PF18709.1 KXS20388.1 - 0.16 11.2 13.1 0.26 10.4 7.3 2.2 1 1 1 2 2 2 0 Dynamin-like helical domain Uso1_p115_C PF04871.13 KXS20388.1 - 0.25 11.7 28.6 2.1 8.7 17.9 2.7 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region GAS PF13851.6 KXS20388.1 - 0.34 10.3 26.2 0.25 10.7 10.2 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF745 PF05335.13 KXS20388.1 - 0.42 10.3 17.1 2 8.1 6.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF745) EzrA PF06160.12 KXS20388.1 - 0.58 8.3 22.0 2.1 6.4 2.4 1.8 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA DUF4200 PF13863.6 KXS20388.1 - 0.66 10.4 29.1 0.063 13.7 3.5 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Fib_alpha PF08702.10 KXS20388.1 - 0.95 9.6 15.3 1.5 9.0 1.8 2.2 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF4407 PF14362.6 KXS20388.1 - 0.97 8.7 15.7 1.4 8.2 15.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Lectin_N PF03954.14 KXS20388.1 - 0.97 9.2 10.4 0.072 12.8 1.0 2.9 1 1 2 3 3 3 0 Hepatic lectin, N-terminal domain DUF3450 PF11932.8 KXS20388.1 - 1.2 8.4 19.8 0.16 11.3 3.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) CLZ PF16526.5 KXS20388.1 - 1.8 9.0 24.7 0.92 9.9 9.7 3.7 1 1 2 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Atg14 PF10186.9 KXS20388.1 - 1.8 7.5 25.8 0.54 9.3 5.7 2.0 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 UPF0242 PF06785.11 KXS20388.1 - 1.9 8.6 27.5 4.2 7.4 17.1 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus TMF_DNA_bd PF12329.8 KXS20388.1 - 1.9 8.5 35.7 0.059 13.4 7.4 3.3 1 1 0 3 3 3 0 TATA element modulatory factor 1 DNA binding COG2 PF06148.11 KXS20388.1 - 2.5 8.2 12.8 6.2 6.9 5.3 2.7 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 FUSC PF04632.12 KXS20388.1 - 2.5 6.5 3.2 3 6.3 3.2 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF1664 PF07889.12 KXS20388.1 - 3 7.9 12.9 6.5 6.8 1.3 2.9 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) ERM PF00769.19 KXS20388.1 - 3.1 7.5 31.2 6.9 6.4 5.5 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family THOC7 PF05615.13 KXS20388.1 - 3.2 8.0 23.0 1.6 9.1 17.2 2.4 1 1 1 2 2 2 0 Tho complex subunit 7 Ax_dynein_light PF10211.9 KXS20388.1 - 5 7.0 21.7 2.3 8.1 3.4 2.5 1 1 1 2 2 2 0 Axonemal dynein light chain DUF948 PF06103.11 KXS20388.1 - 5.2 7.4 7.7 11 6.3 0.7 2.6 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) Syntaxin-6_N PF09177.11 KXS20388.1 - 6.9 7.3 15.1 16 6.1 4.9 2.8 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Striatin PF08232.12 KXS20388.1 - 8.2 7.0 20.9 9.4 6.8 2.3 2.7 1 1 1 2 2 2 0 Striatin family DJ-1_PfpI PF01965.24 KXS20389.1 - 1.9e-46 157.9 0.0 2.1e-46 157.7 0.0 1.0 1 0 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 KXS20389.1 - 0.00059 19.6 0.3 0.0055 16.4 0.1 2.0 1 1 1 2 2 2 1 ThiJ/PfpI family-like GATase PF00117.28 KXS20389.1 - 0.0014 18.4 0.0 0.0021 17.9 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 KXS20389.1 - 0.0018 17.9 0.0 0.0025 17.4 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain GATase_5 PF13507.6 KXS20389.1 - 0.0074 15.4 0.0 0.011 14.9 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Catalase_C PF18011.1 KXS20389.1 - 0.037 13.6 0.0 0.069 12.8 0.0 1.6 1 1 0 1 1 1 0 C-terminal domain found in long catalases Peptidase_C26 PF07722.13 KXS20389.1 - 0.058 13.1 0.1 0.27 10.9 0.1 2.0 1 1 0 1 1 1 0 Peptidase C26 MBOAT_2 PF13813.6 KXS20390.1 - 0.0005 20.3 5.4 0.0013 19.0 5.4 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family MBOAT PF03062.19 KXS20390.1 - 0.0025 17.2 10.6 0.0054 16.1 10.6 1.4 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family DUF4834 PF16118.5 KXS20390.1 - 0.012 16.5 0.8 0.12 13.4 0.2 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) ADH_zinc_N PF00107.26 KXS20391.1 - 7e-22 77.8 0.0 1.3e-21 76.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXS20391.1 - 3.3e-18 65.6 0.2 6.4e-18 64.6 0.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KXS20391.1 - 7.1e-08 33.6 0.0 1.4e-07 32.7 0.0 1.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KXS20391.1 - 4.8e-07 29.5 0.8 0.014 14.9 0.2 2.9 1 1 1 2 2 2 2 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 KXS20391.1 - 2.2e-06 27.1 1.2 3.2e-06 26.6 1.2 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Lactamase_B PF00753.27 KXS20392.1 - 1.9e-11 44.4 2.7 2.8e-10 40.5 2.7 2.4 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily TPR_2 PF07719.17 KXS20392.1 - 2.4e-06 27.2 0.2 0.55 10.5 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KXS20392.1 - 5e-06 27.1 1.5 0.0075 16.9 0.3 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 KXS20392.1 - 0.00042 20.1 1.9 2.1 8.6 0.5 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat Lactamase_B_2 PF12706.7 KXS20392.1 - 0.00074 19.1 0.1 0.0013 18.3 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain TPR_1 PF00515.28 KXS20392.1 - 0.0068 16.2 0.0 1.7 8.6 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 KXS20392.1 - 0.015 15.5 5.0 0.082 13.2 2.1 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 KXS20392.1 - 0.14 12.4 0.0 1.7 9.1 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 KXS20392.1 - 0.21 11.5 4.5 1.2 9.1 0.2 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat CBS PF00571.28 KXS20393.1 - 2.5e-23 82.3 0.3 1.6e-10 41.3 0.0 2.1 2 0 0 2 2 2 2 CBS domain Pkinase PF00069.25 KXS20394.1 - 1e-22 80.8 0.0 1.2e-22 80.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS20394.1 - 8.9e-20 71.1 0.0 1.1e-19 70.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXS20394.1 - 9e-06 24.7 0.0 1e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 KXS20394.1 - 0.063 12.9 0.0 0.077 12.6 0.0 1.1 1 0 0 1 1 1 0 RIO1 family PPR PF01535.20 KXS20395.1 - 0.016 15.4 0.1 2.3 8.7 0.0 2.9 3 0 0 3 3 3 0 PPR repeat GST_N_3 PF13417.6 KXS20396.1 - 1e-13 51.4 0.0 3e-13 50.0 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KXS20396.1 - 5.6e-10 39.4 0.0 1.4e-09 38.1 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KXS20396.1 - 4.6e-09 36.5 0.0 7.4e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KXS20396.1 - 1.2e-06 28.6 0.0 2.7e-06 27.5 0.0 1.5 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KXS20396.1 - 6.8e-06 26.0 0.0 1.8e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KXS20396.1 - 2.4e-05 24.5 0.0 4.1e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 KXS20396.1 - 0.043 14.1 0.0 0.08 13.3 0.0 1.4 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein GST_C_5 PF16865.5 KXS20396.1 - 0.13 12.9 0.0 0.27 11.8 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Pkinase PF00069.25 KXS20397.1 - 2.1e-43 148.6 0.0 3.3e-43 147.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS20397.1 - 1.2e-39 136.1 0.0 1.7e-39 135.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_3 PF13606.6 KXS20397.1 - 6e-08 32.4 0.5 0.054 14.1 0.0 4.5 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.7 KXS20397.1 - 1e-06 29.2 0.0 8.9e-05 23.0 0.0 3.2 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Pkinase_fungal PF17667.1 KXS20397.1 - 2e-05 23.6 0.0 3.4e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Ank PF00023.30 KXS20397.1 - 5e-05 23.6 0.3 1.3 9.6 0.1 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 KXS20397.1 - 0.00052 20.5 0.1 0.077 13.6 0.0 3.0 2 1 0 2 2 1 1 Ankyrin repeats (many copies) Kinase-like PF14531.6 KXS20397.1 - 0.00085 18.7 0.0 0.0014 18.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Ank_5 PF13857.6 KXS20397.1 - 0.0011 19.2 0.1 3.3 8.1 0.1 3.0 3 0 0 3 3 3 2 Ankyrin repeats (many copies) DUF5319 PF17252.2 KXS20397.1 - 0.19 11.9 0.0 0.83 9.9 0.0 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5319) RIO1 PF01163.22 KXS20397.1 - 0.2 11.2 0.0 0.42 10.2 0.0 1.4 1 0 0 1 1 1 0 RIO1 family CBS PF00571.28 KXS20398.1 - 2.3e-23 82.4 0.2 1.4e-10 41.5 0.0 2.1 2 0 0 2 2 2 2 CBS domain Hist_deacetyl PF00850.19 KXS20399.1 - 1.3e-81 274.4 0.0 1.7e-81 274.0 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain IQ PF00612.27 KXS20401.1 - 0.055 13.3 1.1 0.19 11.6 1.1 2.0 1 0 0 1 1 1 0 IQ calmodulin-binding motif Cyclin PF08613.11 KXS20402.1 - 0.031 14.6 0.1 0.094 13.1 0.0 1.8 2 0 0 2 2 2 0 Cyclin Glyco_transf_90 PF05686.12 KXS20403.1 - 1.8e-15 56.8 0.0 5.8e-15 55.1 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferase family 90 ALS_ss_C PF10369.9 KXS20404.1 - 9.8e-22 77.0 0.1 3.5e-19 68.8 0.0 2.9 1 1 2 3 3 3 1 Small subunit of acetolactate synthase ACT PF01842.25 KXS20404.1 - 1.7e-14 53.3 0.1 3.8e-14 52.1 0.1 1.7 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.6 KXS20404.1 - 2.7e-09 36.7 0.0 5.7e-09 35.7 0.0 1.6 1 0 0 1 1 1 1 ACT domain Gag_spuma PF03276.14 KXS20404.1 - 0.029 12.8 0.8 0.037 12.5 0.8 1.1 1 0 0 1 1 1 0 Spumavirus gag protein Imm57 PF15596.6 KXS20404.1 - 0.05 13.9 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 57 Phage_rep_org_N PF09681.10 KXS20404.1 - 0.16 11.9 0.0 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 N-terminal phage replisome organiser (Phage_rep_org_N) NUDIX PF00293.28 KXS20405.1 - 2.2e-15 56.8 0.1 7e-15 55.2 0.0 1.8 2 0 0 2 2 2 1 NUDIX domain NUDIX-like PF09296.11 KXS20405.1 - 6.7e-12 46.0 0.1 1.8e-11 44.6 0.0 1.8 2 0 0 2 2 2 1 NADH pyrophosphatase-like rudimentary NUDIX domain Ank_5 PF13857.6 KXS20405.1 - 1.5e-11 44.3 0.1 4.2e-11 42.9 0.1 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXS20405.1 - 3.3e-08 34.0 0.0 8.1e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXS20405.1 - 2.5e-07 31.1 0.0 8.9e-07 29.4 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) zf-NADH-PPase PF09297.11 KXS20405.1 - 5.7e-07 29.1 2.2 1.4e-06 27.8 2.2 1.7 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain Ank PF00023.30 KXS20405.1 - 1.6e-06 28.3 0.2 2.9e-05 24.3 0.1 2.6 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 KXS20405.1 - 3.2e-06 27.1 0.0 9.2e-06 25.6 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeat Thioredoxin PF00085.20 KXS20406.1 - 2.8e-29 101.1 1.3 3e-22 78.6 0.4 3.4 3 1 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 KXS20406.1 - 3.4e-14 53.2 0.1 6.1e-05 23.0 0.0 3.3 3 0 0 3 3 3 3 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KXS20406.1 - 4.7e-07 30.1 0.3 0.00052 20.3 0.0 3.5 2 2 1 3 3 3 2 Thioredoxin-like Thioredoxin_2 PF13098.6 KXS20406.1 - 1.1e-05 25.8 0.5 0.036 14.5 0.2 3.5 2 1 0 2 2 2 1 Thioredoxin-like domain OST3_OST6 PF04756.13 KXS20406.1 - 0.00012 21.6 0.9 0.19 11.1 0.1 3.2 2 1 0 3 3 3 1 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 KXS20406.1 - 0.00043 20.2 0.2 0.027 14.4 0.1 2.6 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.10 KXS20406.1 - 0.0051 16.5 0.6 0.37 10.5 0.1 2.7 3 0 0 3 3 3 1 Redoxin SPRY PF00622.28 KXS20408.1 - 7.7e-20 71.2 0.3 1.4e-19 70.4 0.3 1.4 1 0 0 1 1 1 1 SPRY domain HEAT_2 PF13646.6 KXS20408.1 - 0.014 15.7 8.8 0.054 13.9 2.8 4.1 3 1 1 4 4 4 0 HEAT repeats V-ATPase_H_C PF11698.8 KXS20408.1 - 0.089 12.9 0.0 2 8.6 0.0 3.1 4 0 0 4 4 4 0 V-ATPase subunit H HEAT PF02985.22 KXS20408.1 - 1.5 9.2 5.4 32 5.1 0.4 4.3 3 0 0 3 3 3 0 HEAT repeat Cullin PF00888.22 KXS20409.1 - 3.6e-124 415.7 0.7 4.7e-124 415.3 0.7 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KXS20409.1 - 1.1e-26 92.7 0.7 2.8e-26 91.3 0.7 1.8 1 0 0 1 1 1 1 Cullin protein neddylation domain HTH_IclR PF09339.10 KXS20409.1 - 0.031 14.1 0.0 0.17 11.7 0.1 2.3 2 0 0 2 2 2 0 IclR helix-turn-helix domain MarR PF01047.22 KXS20409.1 - 0.058 13.3 0.0 3.7 7.6 0.0 3.3 3 0 0 3 3 3 0 MarR family E1-E2_ATPase PF00122.20 KXS20410.1 - 2.3e-51 173.9 0.1 2.3e-51 173.9 0.1 2.4 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KXS20410.1 - 7.6e-46 156.1 7.7 1.2e-45 155.5 3.7 2.4 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KXS20410.1 - 5.9e-20 72.5 0.7 3.9e-19 69.8 0.7 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KXS20410.1 - 4.4e-16 58.3 0.2 1.5e-15 56.6 0.0 2.1 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 KXS20410.1 - 1e-15 57.6 0.0 2.1e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KXS20410.1 - 3.3e-06 27.0 1.8 2.7e-05 24.0 1.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase WD40 PF00400.32 KXS20411.1 - 7e-05 23.5 2.0 3.7 8.6 0.0 4.6 4 0 0 4 4 4 3 WD domain, G-beta repeat PG_binding_3 PF09374.10 KXS20411.1 - 0.17 12.2 0.1 0.54 10.6 0.1 1.9 1 0 0 1 1 1 0 Predicted Peptidoglycan domain RhoGAP PF00620.27 KXS20412.1 - 7e-51 172.1 0.0 1.1e-50 171.4 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain WW PF00397.26 KXS20412.1 - 2.2e-20 72.4 10.0 3e-10 40.0 0.8 2.4 2 0 0 2 2 2 2 WW domain SH3_9 PF14604.6 KXS20412.1 - 4.2e-12 45.7 0.3 1.1e-11 44.4 0.3 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXS20412.1 - 5e-10 38.8 0.4 1.7e-09 37.1 0.4 2.0 1 0 0 1 1 1 1 SH3 domain PH PF00169.29 KXS20412.1 - 1.1e-08 35.5 0.0 2.3e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 PH domain SH3_2 PF07653.17 KXS20412.1 - 2.1e-06 27.3 0.1 6e-06 25.8 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain Glyco_hyd_101C PF17451.2 KXS20412.1 - 0.00028 21.2 0.4 0.039 14.2 0.1 2.5 2 0 0 2 2 2 1 Glycosyl hydrolase 101 beta sandwich domain PH_9 PF15410.6 KXS20412.1 - 0.044 14.1 0.0 0.11 12.9 0.0 1.6 1 1 0 1 1 1 0 Pleckstrin homology domain DUF1708 PF08101.11 KXS20412.1 - 0.074 12.2 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1708) Ribosomal_S19 PF00203.21 KXS20413.1 - 2e-35 120.5 1.9 2.7e-35 120.1 1.9 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 FliH PF02108.16 KXS20413.1 - 0.0047 17.0 0.1 0.0067 16.5 0.1 1.2 1 0 0 1 1 1 1 Flagellar assembly protein FliH Mucin PF01456.17 KXS20414.1 - 0.0024 17.9 6.8 0.0024 17.9 6.8 2.9 4 0 0 4 4 4 1 Mucin-like glycoprotein SPT6_acidic PF14632.6 KXS20414.1 - 0.52 10.9 12.5 0.19 12.3 1.1 2.4 1 1 0 2 2 2 0 Acidic N-terminal SPT6 SVIP PF15811.5 KXS20414.1 - 7 7.2 10.2 1.2 9.6 2.3 2.6 2 0 0 2 2 2 0 Small VCP/p97-interacting protein Nop52 PF05997.12 KXS20415.1 - 1.2e-53 182.1 0.0 1.6e-53 181.7 0.0 1.1 1 0 0 1 1 1 1 Nucleolar protein,Nop52 zf-met PF12874.7 KXS20416.1 - 2.8e-07 30.7 0.1 4.3e-07 30.1 0.1 1.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KXS20416.1 - 7.9e-07 29.2 0.1 1.3e-06 28.6 0.1 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-U1 PF06220.12 KXS20416.1 - 0.00054 19.7 0.1 0.00099 18.8 0.1 1.4 1 0 0 1 1 1 1 U1 zinc finger SNRNP27 PF08648.12 KXS20416.1 - 0.0045 17.0 0.4 0.0045 17.0 0.4 1.9 2 0 0 2 2 2 1 U4/U6.U5 small nuclear ribonucleoproteins zf-C2H2 PF00096.26 KXS20416.1 - 0.16 12.5 0.2 0.35 11.4 0.2 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type PTPRCAP PF15713.5 KXS20416.1 - 1.3 9.3 12.4 0.17 12.1 4.3 2.3 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated DUF4211 PF13926.6 KXS20417.1 - 5.4e-20 71.9 0.0 9.6e-20 71.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4211) TrmB PF01978.19 KXS20417.1 - 0.037 13.9 0.2 4 7.4 0.0 3.3 3 0 0 3 3 3 0 Sugar-specific transcriptional regulator TrmB DUF1848 PF08902.11 KXS20419.1 - 0.0098 15.6 0.0 0.037 13.7 0.0 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF1848) Ribosomal_60s PF00428.19 KXS20420.1 - 1.4e-23 83.2 25.2 4.6e-23 81.6 25.2 1.7 1 1 0 1 1 1 1 60s Acidic ribosomal protein Cytomega_UL84 PF06284.11 KXS20420.1 - 0.028 12.9 2.8 0.032 12.7 2.8 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein DUF5327 PF17261.2 KXS20420.1 - 0.064 14.0 1.0 0.081 13.7 1.0 1.3 1 1 0 1 1 1 0 Family of unknown function (DUF5327) DUF3391 PF11871.8 KXS20420.1 - 0.35 11.4 3.0 0.45 11.0 3.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) DUF1206 PF06724.11 KXS20421.1 - 0.0071 16.4 4.7 0.0071 16.4 4.7 3.2 4 0 0 4 4 4 1 Domain of Unknown Function (DUF1206) GET2 PF08690.10 KXS20421.1 - 0.96 9.1 7.7 25 4.4 0.2 3.8 3 1 0 3 3 3 0 GET complex subunit GET2 CD99L2 PF12301.8 KXS20422.1 - 9.4 6.5 13.8 0.16 12.2 6.9 1.5 2 0 0 2 2 2 0 CD99 antigen like protein 2 LRR_4 PF12799.7 KXS20423.1 - 2.6e-11 43.5 33.2 7.7e-06 26.2 0.4 6.5 4 2 4 8 8 8 5 Leucine Rich repeats (2 copies) REJ PF02010.15 KXS20423.1 - 1.6e-09 37.1 0.2 3.5e-09 36.0 0.2 1.4 1 0 0 1 1 1 1 REJ domain LRR_8 PF13855.6 KXS20423.1 - 1.5e-05 24.7 34.6 0.0093 15.7 2.1 6.2 3 1 3 6 6 6 5 Leucine rich repeat LRR_1 PF00560.33 KXS20423.1 - 0.00038 20.6 25.5 0.88 10.4 0.1 10.1 8 2 1 9 9 9 1 Leucine Rich Repeat LRR_6 PF13516.6 KXS20423.1 - 0.0011 18.8 27.1 1 9.6 0.1 8.4 8 0 0 8 8 8 4 Leucine Rich repeat DUF4476 PF14771.6 KXS20423.1 - 0.092 13.1 0.0 1.5 9.2 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4476) INTS2 PF14750.6 KXS20425.1 - 3.8e-15 54.6 0.0 8.4e-14 50.1 0.0 2.2 2 1 0 2 2 2 2 Integrator complex subunit 2 Rdx PF10262.9 KXS20426.1 - 2e-13 50.3 0.0 2.8e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 Rdx family EDR1 PF14381.6 KXS20427.1 - 4.6e-28 98.3 0.0 5.4e-15 55.6 0.0 2.6 3 0 0 3 3 3 2 Ethylene-responsive protein kinase Le-CTR1 Arm PF00514.23 KXS20427.1 - 2.8e-22 78.0 10.2 4.6e-12 45.5 0.1 4.8 5 1 0 5 5 5 3 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 KXS20427.1 - 1.9e-07 31.4 4.7 1.1e-06 28.9 2.5 2.8 2 1 0 2 2 2 1 HEAT repeats HEAT_EZ PF13513.6 KXS20427.1 - 9.2e-06 26.0 3.8 0.00042 20.8 0.9 3.7 2 1 1 3 3 3 2 HEAT-like repeat HEAT PF02985.22 KXS20427.1 - 2.8e-05 24.0 6.0 0.15 12.4 0.2 4.0 3 0 0 3 3 3 2 HEAT repeat Proteasom_PSMB PF10508.9 KXS20427.1 - 0.017 13.7 0.0 0.023 13.2 0.0 1.1 1 0 0 1 1 1 0 Proteasome non-ATPase 26S subunit K-cyclin_vir_C PF09080.10 KXS20427.1 - 1.8 9.0 7.0 2.8 8.4 0.8 2.7 2 1 0 2 2 2 0 K cyclin, C terminal DHHC PF01529.20 KXS20428.1 - 6.9e-35 120.1 13.8 6.9e-35 120.1 13.8 2.5 2 1 0 2 2 2 1 DHHC palmitoyltransferase Ank_2 PF12796.7 KXS20428.1 - 1.2e-30 106.0 2.4 1.4e-16 60.9 0.2 4.1 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXS20428.1 - 3.3e-29 100.9 2.3 5.2e-10 39.7 0.2 4.8 2 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXS20428.1 - 3.1e-24 84.7 8.0 2.2e-08 34.2 0.4 4.4 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXS20428.1 - 1.7e-22 77.1 1.6 0.0032 17.8 0.0 7.7 7 0 0 7 7 7 5 Ankyrin repeat Ank PF00023.30 KXS20428.1 - 1.1e-18 66.8 6.6 2.4e-05 24.5 0.0 7.5 8 0 0 8 8 8 4 Ankyrin repeat IF-2B PF01008.17 KXS20429.1 - 4.7e-68 229.4 0.0 5.4e-68 229.2 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family RPN7 PF10602.9 KXS20430.1 - 7.7e-56 188.5 0.4 1.2e-55 187.9 0.4 1.2 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 KXS20430.1 - 1.7e-14 54.2 0.3 5.5e-14 52.5 0.0 2.0 2 0 0 2 2 2 1 PCI domain SAC3_GANP PF03399.16 KXS20430.1 - 0.021 14.2 0.2 0.039 13.4 0.2 1.3 1 0 0 1 1 1 0 SAC3/GANP family Sugarporin_N PF11471.8 KXS20430.1 - 0.03 14.3 1.1 0.073 13.0 1.1 1.6 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension HTH_DeoR PF08220.12 KXS20430.1 - 0.09 12.5 0.0 0.23 11.3 0.0 1.7 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain Fe-S_assembly PF04384.13 KXS20430.1 - 0.15 12.7 0.0 5.2 7.8 0.0 2.5 2 0 0 2 2 2 0 Iron-sulphur cluster assembly TPR_2 PF07719.17 KXS20430.1 - 0.28 11.4 1.2 2.3 8.6 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Pkinase_Tyr PF07714.17 KXS20432.1 - 4.5e-48 163.8 0.0 3.2e-46 157.7 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXS20432.1 - 2.5e-43 148.3 0.0 7.3e-42 143.5 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KXS20432.1 - 0.019 13.7 0.0 0.026 13.3 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 KXS20432.1 - 0.026 13.9 0.1 0.12 11.7 0.1 1.9 1 1 0 1 1 1 0 Kinase-like Kdo PF06293.14 KXS20432.1 - 0.028 13.7 0.0 0.039 13.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DnaJ_C PF01556.18 KXS20433.1 - 9.6e-46 155.5 0.7 1.3e-45 155.1 0.7 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KXS20433.1 - 6.4e-26 90.3 1.8 1e-25 89.6 1.8 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KXS20433.1 - 2.8e-16 59.6 20.1 5.5e-16 58.7 20.1 1.5 1 0 0 1 1 1 1 DnaJ central domain DZR PF12773.7 KXS20433.1 - 0.034 14.2 7.6 0.31 11.1 1.1 2.3 2 0 0 2 2 2 0 Double zinc ribbon HypA PF01155.19 KXS20433.1 - 0.038 14.0 11.0 1.2 9.1 0.7 2.4 1 1 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Anti-TRAP PF15777.5 KXS20433.1 - 0.23 11.5 17.7 0.59 10.1 3.0 2.5 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein zinc-ribbons_6 PF07191.12 KXS20433.1 - 1 9.4 8.9 6.6 6.8 8.5 2.1 1 1 1 2 2 2 0 zinc-ribbons A2L_zn_ribbon PF08792.10 KXS20433.1 - 8 6.3 15.3 1.5 8.6 3.8 3.7 3 1 1 4 4 4 0 A2L zinc ribbon domain U3_assoc_6 PF08640.11 KXS20434.1 - 3.7e-27 94.2 0.6 8.5e-27 93.0 0.6 1.6 1 0 0 1 1 1 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.6 KXS20434.1 - 8.5e-08 32.4 1.6 0.0074 17.0 0.4 3.8 1 1 2 3 3 3 2 Tetratricopeptide repeat NRDE-2 PF08424.10 KXS20434.1 - 0.017 14.3 1.2 0.18 10.9 1.2 2.1 1 1 0 1 1 1 0 NRDE-2, necessary for RNA interference TPR_17 PF13431.6 KXS20434.1 - 0.075 13.5 0.1 39 5.0 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat UCH PF00443.29 KXS20438.1 - 4.9e-33 114.7 0.0 1e-32 113.7 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KXS20438.1 - 2.8e-05 23.9 0.2 0.05 13.2 0.0 2.7 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.6 KXS20438.1 - 0.098 12.6 0.0 0.29 11.1 0.0 1.8 2 0 0 2 2 2 0 A repeated domain in UCH-protein TPR_17 PF13431.6 KXS20440.1 - 0.00014 22.0 0.1 1.6 9.3 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 KXS20440.1 - 0.00092 19.1 0.6 0.26 11.5 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 KXS20440.1 - 0.0011 19.4 0.5 0.025 15.1 0.3 2.7 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 KXS20440.1 - 0.0011 18.7 0.0 0.062 13.2 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 KXS20440.1 - 0.0017 19.0 6.7 0.014 16.1 5.2 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KXS20440.1 - 0.0022 18.1 0.0 0.0041 17.3 0.0 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 KXS20440.1 - 0.018 15.8 8.6 0.063 14.1 1.3 4.1 3 1 2 5 5 5 0 Tetratricopeptide repeat PhyH PF05721.13 KXS20441.1 - 3.2e-06 27.6 0.0 9.3e-06 26.0 0.0 1.8 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) AMP-binding PF00501.28 KXS20442.1 - 3.9e-92 309.0 0.0 4.9e-92 308.7 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXS20442.1 - 1e-19 71.3 0.1 8.9e-17 61.8 0.0 2.6 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain zf-UBR PF02207.20 KXS20443.1 - 2.6e-17 62.7 6.5 2.6e-17 62.7 6.5 2.1 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 KXS20443.1 - 3e-08 33.3 0.0 9.2e-08 31.8 0.0 1.8 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS DUF1682 PF07946.14 KXS20443.1 - 1.3 8.2 5.4 2.8 7.1 5.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) F-box-like PF12937.7 KXS20445.1 - 0.0049 16.7 0.1 0.01 15.7 0.1 1.5 1 0 0 1 1 1 1 F-box-like Ion_trans_2 PF07885.16 KXS20447.1 - 2.9e-24 84.8 29.9 5.9e-13 48.6 11.4 3.0 3 0 0 3 3 3 2 Ion channel Pectate_lyase PF03211.13 KXS20448.1 - 3.9e-46 157.2 1.7 5.6e-46 156.7 1.7 1.2 1 0 0 1 1 1 1 Pectate lyase Pho88 PF10032.9 KXS20449.1 - 0.022 14.0 0.4 0.026 13.8 0.4 1.2 1 0 0 1 1 1 0 Phosphate transport (Pho88) Cadherin_C_2 PF16492.5 KXS20449.1 - 0.068 13.9 0.8 0.083 13.6 0.8 1.2 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal Pho88 PF10032.9 KXS20451.1 - 0.054 12.8 0.3 0.069 12.4 0.3 1.2 1 0 0 1 1 1 0 Phosphate transport (Pho88) RAB3GAP2_N PF14655.6 KXS20453.1 - 2.4e-13 50.2 0.0 4.8e-13 49.2 0.0 1.4 1 1 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit N-terminus RAB3GAP2_N PF14655.6 KXS20454.1 - 7.1e-24 84.8 0.0 8.8e-24 84.5 0.0 1.1 1 0 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit N-terminus ADH_zinc_N PF00107.26 KXS20455.1 - 2.3e-30 105.2 0.5 5.1e-30 104.1 0.5 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXS20455.1 - 1.4e-27 95.7 0.2 1.4e-27 95.7 0.2 2.3 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KXS20455.1 - 9.3e-11 42.9 0.0 1.9e-10 41.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KXS20455.1 - 3e-08 33.4 1.0 4.5e-08 32.8 1.0 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 KXS20455.1 - 0.036 13.4 4.1 0.071 12.4 4.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 KXS20455.1 - 0.079 12.3 0.2 0.14 11.5 0.2 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 KXS20455.1 - 0.13 12.5 0.6 0.24 11.7 0.6 1.4 1 0 0 1 1 1 0 TrkA-N domain ThiF PF00899.21 KXS20455.1 - 0.22 10.8 1.3 0.4 10.0 1.3 1.5 1 0 0 1 1 1 0 ThiF family Metallopep PF12044.8 KXS20456.1 - 1.5e-80 270.9 0.0 4.4e-80 269.4 0.0 1.7 1 1 0 1 1 1 1 Putative peptidase family Peptidase_M11 PF05548.11 KXS20456.1 - 0.1 11.7 0.1 0.15 11.2 0.1 1.2 1 0 0 1 1 1 0 Gametolysin peptidase M11 Peptidase_M66 PF10462.9 KXS20456.1 - 0.15 11.0 1.0 0.26 10.2 1.0 1.2 1 0 0 1 1 1 0 Peptidase M66 Metallophos PF00149.28 KXS20457.1 - 2.4e-09 38.0 0.0 3.5e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KXS20457.1 - 2.7e-08 34.2 0.0 1.8e-07 31.5 0.0 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain NAD_binding_1 PF00175.21 KXS20459.1 - 1.7e-17 64.0 0.0 2.7e-17 63.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KXS20459.1 - 1.3e-05 25.4 0.0 5.3e-05 23.5 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KXS20459.1 - 0.012 15.7 0.0 0.98 9.5 0.0 2.2 2 0 0 2 2 2 0 Ferric reductase NAD binding domain COX14 PF14880.6 KXS20459.1 - 0.13 12.1 0.1 0.23 11.3 0.1 1.3 1 0 0 1 1 1 0 Cytochrome oxidase c assembly PALP PF00291.25 KXS20460.1 - 3.4e-60 203.9 0.2 7.2e-60 202.9 0.2 1.6 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF953 PF06110.11 KXS20460.1 - 1.4e-12 47.3 0.0 2.5e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) DFP PF04127.15 KXS20460.1 - 0.079 12.8 0.1 0.14 12.0 0.1 1.4 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein ECH_1 PF00378.20 KXS20461.1 - 1.8e-45 155.2 0.0 2.2e-45 154.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXS20461.1 - 8.4e-17 61.7 0.1 9.6e-17 61.5 0.1 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 KXS20461.1 - 0.091 12.7 0.0 0.46 10.4 0.0 1.9 2 0 0 2 2 2 0 Peptidase family S49 FAA_hydrolase PF01557.18 KXS20462.1 - 1.7e-57 194.6 0.0 1.9e-57 194.4 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family SH3_9 PF14604.6 KXS20463.1 - 3e-12 46.2 0.0 7.7e-12 44.9 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXS20463.1 - 7.4e-10 38.3 1.0 1e-09 37.8 0.0 1.8 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 KXS20463.1 - 7.1e-09 35.2 0.0 1.5e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.11 KXS20463.1 - 0.00072 19.8 0.0 0.0016 18.6 0.0 1.6 1 0 0 1 1 1 1 Bacterial SH3 domain SH3_4 PF06347.13 KXS20463.1 - 0.0013 18.5 0.1 0.003 17.3 0.1 1.6 1 0 0 1 1 1 1 Bacterial SH3 domain SH3_10 PF17902.1 KXS20463.1 - 0.0051 16.9 0.0 0.016 15.3 0.0 1.7 2 0 0 2 2 2 1 SH3 domain hSH3 PF14603.6 KXS20463.1 - 0.1 13.0 0.0 0.2 12.1 0.0 1.3 1 0 0 1 1 1 0 Helically-extended SH3 domain CR6_interact PF10147.9 KXS20464.1 - 0.22 11.2 5.6 0.42 10.3 5.6 1.4 1 0 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 Trypan_glycop PF00913.19 KXS20464.1 - 0.41 9.9 4.8 0.66 9.2 4.8 1.2 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein (A-type) RNA12 PF10443.9 KXS20465.1 - 2.1e-89 300.3 0.0 1.4e-49 169.0 0.0 2.1 1 1 1 2 2 2 2 RNA12 protein RRM_1 PF00076.22 KXS20465.1 - 1.9e-07 30.8 0.0 6.2e-07 29.1 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ATPase_2 PF01637.18 KXS20465.1 - 0.00071 19.6 0.0 0.0019 18.2 0.0 1.6 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_28 PF13521.6 KXS20465.1 - 0.019 15.2 0.1 1 9.6 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KXS20465.1 - 0.12 12.8 1.4 0.65 10.4 0.2 2.7 3 0 0 3 3 3 0 AAA ATPase domain ADH_zinc_N PF00107.26 KXS20466.1 - 1.4e-30 106.0 0.6 2.9e-30 104.9 0.6 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXS20466.1 - 2.4e-29 101.4 0.3 2.4e-29 101.4 0.3 2.2 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KXS20466.1 - 2.6e-12 47.9 0.0 4.7e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KXS20466.1 - 3.5e-09 36.5 1.0 5.1e-09 35.9 1.0 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 KXS20466.1 - 0.02 14.2 4.1 0.04 13.2 4.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ThiF PF00899.21 KXS20466.1 - 0.11 11.8 1.7 0.19 11.0 1.7 1.4 1 0 0 1 1 1 0 ThiF family TrkA_N PF02254.18 KXS20466.1 - 0.15 12.3 0.7 0.27 11.5 0.7 1.4 1 0 0 1 1 1 0 TrkA-N domain p450 PF00067.22 KXS20467.1 - 3.6e-63 213.9 0.0 4.4e-63 213.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1147 PF06615.11 KXS20467.1 - 0.17 11.9 0.5 10 6.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1147) ECH_1 PF00378.20 KXS20468.1 - 2.8e-48 164.4 0.0 3.6e-48 164.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXS20468.1 - 1.2e-23 84.2 0.1 3.9e-23 82.5 0.1 1.7 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase PsiA PF06952.11 KXS20469.1 - 0.91 8.7 9.7 0.13 11.4 5.4 1.7 2 0 0 2 2 2 0 PsiA protein HAUS6_N PF14661.6 KXS20469.1 - 1.2 8.7 7.9 0.21 11.2 2.6 1.9 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus DUF2098 PF09871.9 KXS20469.1 - 2.4 8.6 4.6 0.96 9.8 1.9 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2098) HK_sensor PF16750.5 KXS20469.1 - 3.2 8.1 6.7 13 6.1 6.6 1.9 1 1 1 2 2 2 0 Sensor domain of 2-component histidine kinase Pkinase_Tyr PF07714.17 KXS20470.1 - 1.6e-40 139.1 0.0 2.1e-40 138.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXS20470.1 - 1.9e-29 102.9 0.0 2.7e-29 102.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 KXS20470.1 - 0.0024 17.2 0.0 0.0041 16.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KXS20470.1 - 0.0039 17.1 0.1 0.016 15.1 0.1 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family SH3_9 PF14604.6 KXS20470.1 - 0.0081 16.0 0.1 0.019 14.8 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain Kdo PF06293.14 KXS20470.1 - 0.022 14.1 0.0 0.04 13.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SH3_2 PF07653.17 KXS20470.1 - 0.042 13.5 0.0 0.089 12.5 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain SH3_1 PF00018.28 KXS20470.1 - 0.055 13.1 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 SH3 domain HhH-GPD PF00730.25 KXS20471.1 - 3.2e-09 37.2 0.0 6.6e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Pol_alpha_B_N PF08418.10 KXS20471.1 - 4 7.3 6.0 8.8 6.2 0.7 2.1 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal Glyco_hydro_16 PF00722.21 KXS20472.1 - 2.1e-24 85.9 4.2 3.8e-24 85.1 4.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 CBM_1 PF00734.18 KXS20472.1 - 7.8e-06 25.8 23.4 0.00011 22.0 13.9 3.3 2 0 0 2 2 2 2 Fungal cellulose binding domain DUF1080 PF06439.11 KXS20472.1 - 0.0054 16.9 6.8 0.012 15.7 6.8 1.6 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1080) CAP_N PF01213.19 KXS20472.1 - 0.21 11.1 15.6 0.04 13.4 8.9 2.3 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal NUDIX PF00293.28 KXS20473.1 - 1.3e-15 57.6 0.0 2.4e-15 56.7 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Ank_2 PF12796.7 KXS20473.1 - 2e-15 57.1 0.0 7.9e-15 55.2 0.0 2.0 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXS20473.1 - 1.6e-12 47.6 0.0 1.2e-08 35.3 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXS20473.1 - 2.2e-11 43.7 0.2 8.5e-09 35.5 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) NUDIX-like PF09296.11 KXS20473.1 - 3.3e-10 40.5 0.0 3.7e-08 33.9 0.0 2.9 3 0 0 3 3 3 1 NADH pyrophosphatase-like rudimentary NUDIX domain Ank PF00023.30 KXS20473.1 - 1.1e-09 38.3 0.0 2e-05 24.8 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 KXS20473.1 - 3e-08 33.3 0.0 0.00028 21.1 0.0 3.6 3 0 0 3 3 3 1 Ankyrin repeat zf-NADH-PPase PF09297.11 KXS20473.1 - 0.34 10.6 3.8 0.68 9.6 3.8 1.5 1 0 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain NmrA PF05368.13 KXS20474.1 - 2.8e-40 138.4 0.0 3.5e-40 138.0 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXS20474.1 - 4.3e-17 62.6 0.0 5.7e-17 62.2 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KXS20474.1 - 1.5e-08 34.0 0.0 4e-08 32.6 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KXS20474.1 - 0.001 18.6 0.0 0.01 15.3 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KXS20474.1 - 0.075 13.3 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Pyr_redox_2 PF07992.14 KXS20475.1 - 5.7e-50 170.2 0.0 1e-49 169.4 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXS20475.1 - 2.9e-16 59.8 1.9 4.7e-16 59.1 1.0 1.8 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KXS20475.1 - 6.7e-12 45.6 0.5 1.7e-11 44.3 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_3 PF13738.6 KXS20475.1 - 5.8e-07 29.1 0.0 3.5e-06 26.5 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXS20475.1 - 3.3e-06 26.9 1.6 0.0024 17.5 0.6 3.2 3 0 0 3 3 3 1 FAD dependent oxidoreductase Rhodanese PF00581.20 KXS20475.1 - 1.4e-05 25.6 0.0 0.00037 21.0 0.0 2.3 2 0 0 2 2 2 1 Rhodanese-like domain AlaDh_PNT_C PF01262.21 KXS20475.1 - 0.00018 20.9 0.4 0.00032 20.1 0.4 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 KXS20475.1 - 0.00024 20.3 0.8 0.0051 15.9 0.6 2.2 2 0 0 2 2 2 1 FAD binding domain NAD_binding_7 PF13241.6 KXS20475.1 - 0.00074 19.9 0.1 0.0037 17.7 0.1 2.1 2 0 0 2 2 2 1 Putative NAD(P)-binding HI0933_like PF03486.14 KXS20475.1 - 0.00096 18.0 0.3 0.026 13.2 0.1 2.7 3 0 0 3 3 3 1 HI0933-like protein FAD_binding_3 PF01494.19 KXS20475.1 - 0.002 17.5 0.0 0.0033 16.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KXS20475.1 - 0.0035 17.5 0.4 0.011 16.0 0.2 1.9 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain TrkA_N PF02254.18 KXS20475.1 - 0.0036 17.6 0.2 0.0091 16.2 0.2 1.8 1 1 0 1 1 1 1 TrkA-N domain 3HCDH_N PF02737.18 KXS20475.1 - 0.0061 16.5 0.1 0.011 15.6 0.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.22 KXS20475.1 - 0.0062 15.7 0.3 0.012 14.7 0.3 1.5 1 1 0 1 1 1 1 Glucose inhibited division protein A K_oxygenase PF13434.6 KXS20475.1 - 0.01 15.0 0.0 0.028 13.6 0.0 1.6 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) DUF1188 PF06690.11 KXS20475.1 - 0.013 15.0 0.0 0.025 14.1 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1188) NAD_binding_9 PF13454.6 KXS20475.1 - 0.018 15.0 0.2 0.6 10.1 0.1 3.0 2 1 1 3 3 3 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KXS20475.1 - 0.03 13.4 0.5 2.3 7.2 0.1 2.4 2 1 1 3 3 3 0 Lycopene cyclase protein UDPG_MGDP_dh_N PF03721.14 KXS20475.1 - 0.05 13.2 0.3 0.096 12.3 0.3 1.5 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Shikimate_DH PF01488.20 KXS20475.1 - 0.078 13.0 0.1 0.25 11.4 0.0 1.9 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FAD_oxidored PF12831.7 KXS20475.1 - 0.13 11.6 1.1 0.2 10.9 0.7 1.5 1 1 0 1 1 1 0 FAD dependent oxidoreductase ACPS PF01648.20 KXS20477.1 - 2.2e-07 31.0 0.0 8.3e-07 29.1 0.0 1.8 2 0 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily Regnase_1_C PF18561.1 KXS20477.1 - 0.13 12.0 0.0 0.3 10.8 0.0 1.6 1 0 0 1 1 1 0 Endoribonuclease Regnase 1/ ZC3H12 C-terminal domain PepSY_2 PF13670.6 KXS20477.1 - 0.22 11.6 1.4 0.71 9.9 1.4 1.9 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain HSP90 PF00183.18 KXS20478.1 - 5.3e-93 312.7 0.0 6.9e-90 302.4 0.0 2.1 1 1 1 2 2 2 2 Hsp90 protein HATPase_c_3 PF13589.6 KXS20478.1 - 3.8e-08 33.3 0.1 7.7e-08 32.3 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KXS20478.1 - 7.2e-06 26.5 0.1 1.5e-05 25.4 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Aldose_epim PF01263.20 KXS20479.1 - 1.7e-48 165.4 0.4 2.6e-25 89.3 0.1 2.1 2 0 0 2 2 2 2 Aldose 1-epimerase TPT PF03151.16 KXS20480.1 - 1.2e-43 149.6 16.8 3.1e-39 135.1 9.0 2.0 2 0 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.20 KXS20480.1 - 4.5e-06 26.9 32.8 0.0012 19.0 2.3 3.4 3 1 0 3 3 3 2 EamA-like transporter family UAA PF08449.11 KXS20480.1 - 0.00081 18.7 11.7 0.00081 18.7 11.7 2.1 2 1 0 2 2 2 1 UAA transporter family Fzo_mitofusin PF04799.13 KXS20480.1 - 0.085 12.4 0.1 0.17 11.4 0.1 1.4 1 0 0 1 1 1 0 fzo-like conserved region RhoGAP PF00620.27 KXS20481.1 - 0.12 12.2 0.0 0.25 11.2 0.0 1.5 2 0 0 2 2 2 0 RhoGAP domain Mitochondr_Som1 PF11093.8 KXS20482.1 - 2.1e-11 43.7 0.0 2.5e-11 43.4 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial export protein Som1 FIBP PF05427.11 KXS20484.1 - 7.2e-51 173.6 0.0 1.1e-20 74.2 0.0 3.4 4 0 0 4 4 4 3 Acidic fibroblast growth factor binding (FIBP) F-box-like PF12937.7 KXS20485.1 - 0.00053 19.8 0.1 0.0016 18.3 0.1 1.9 1 0 0 1 1 1 1 F-box-like STAS PF01740.21 KXS20485.1 - 0.0063 16.1 0.0 0.068 12.8 0.0 2.5 2 1 0 2 2 2 1 STAS domain F-box PF00646.33 KXS20485.1 - 0.012 15.5 0.8 0.042 13.8 0.1 2.2 2 0 0 2 2 2 0 F-box domain LRR_4 PF12799.7 KXS20485.1 - 0.029 14.8 0.2 6.9 7.2 0.0 3.1 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KXS20485.1 - 0.45 10.7 1.9 5.7 7.2 0.7 3.4 4 0 0 4 4 4 0 Leucine Rich repeat Pirin PF02678.16 KXS20486.1 - 3.2e-35 120.4 0.0 5.1e-35 119.7 0.0 1.3 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 KXS20486.1 - 8.2e-21 74.3 0.0 8.4e-19 67.9 0.0 2.4 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.11 KXS20486.1 - 0.012 15.3 1.2 0.044 13.5 0.4 2.1 2 0 0 2 2 2 0 Cupin domain Cupin_3 PF05899.12 KXS20486.1 - 0.045 13.4 0.1 0.52 10.0 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF861) DUF1664 PF07889.12 KXS20487.1 - 2.4 8.2 23.9 29 4.7 0.3 6.6 4 3 2 6 6 6 0 Protein of unknown function (DUF1664) FAD_binding_3 PF01494.19 KXS20488.1 - 9.2e-23 81.0 0.0 4.4e-22 78.8 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KXS20488.1 - 6.2e-10 38.3 0.2 0.00035 19.4 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_2 PF07992.14 KXS20488.1 - 8e-09 35.1 0.1 0.0042 16.4 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXS20488.1 - 2e-07 30.9 2.0 0.0034 17.0 0.9 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KXS20488.1 - 7.5e-05 22.1 0.0 0.26 10.5 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXS20488.1 - 0.00016 22.2 0.1 0.48 11.0 0.1 2.9 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXS20488.1 - 0.00027 21.0 1.4 0.56 10.2 0.1 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding Amino_oxidase PF01593.24 KXS20488.1 - 0.00044 19.7 0.0 0.00076 18.9 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 KXS20488.1 - 0.00063 19.2 0.1 0.00093 18.7 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KXS20488.1 - 0.00072 18.7 1.3 0.0013 18.0 1.3 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KXS20488.1 - 0.0041 17.3 2.5 0.0059 16.8 1.4 1.9 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KXS20488.1 - 0.0086 15.2 0.5 1.1 8.2 0.0 2.6 3 0 0 3 3 3 1 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 KXS20488.1 - 0.016 14.5 2.3 0.09 12.1 0.1 2.5 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 KXS20488.1 - 0.025 13.7 0.1 0.034 13.2 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Glu_dehyd_C PF16912.5 KXS20488.1 - 0.062 12.8 0.1 0.13 11.8 0.1 1.5 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus SE PF08491.10 KXS20488.1 - 0.068 12.2 0.0 0.34 9.9 0.0 1.9 2 0 0 2 2 2 0 Squalene epoxidase Myb_DNA-binding PF00249.31 KXS20489.1 - 0.064 13.5 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain Glyco_hydro_28 PF00295.17 KXS20490.1 - 1.3e-74 251.2 13.0 1.7e-74 250.8 13.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 DUF1488 PF07369.11 KXS20491.1 - 0.014 15.3 9.8 12 6.0 0.1 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF1488) Defb50 PF17546.2 KXS20491.1 - 0.025 14.5 26.3 1.4 8.9 2.0 4.4 4 0 0 4 4 4 0 Beta defensin 50 Arm PF00514.23 KXS20492.1 - 1.3e-16 60.0 19.6 6.3e-05 22.9 0.0 7.3 7 0 0 7 7 7 4 Armadillo/beta-catenin-like repeat HEAT PF02985.22 KXS20492.1 - 5.3e-12 44.9 9.8 0.0011 19.1 0.0 6.5 5 0 0 5 5 5 4 HEAT repeat HEAT_2 PF13646.6 KXS20492.1 - 3.1e-09 37.1 19.8 0.00078 19.8 0.4 5.4 2 1 3 5 5 5 4 HEAT repeats HEAT_EZ PF13513.6 KXS20492.1 - 5e-08 33.3 33.0 5.1e-05 23.7 0.6 6.9 6 3 2 8 8 8 4 HEAT-like repeat Cnd1 PF12717.7 KXS20492.1 - 9.3e-08 32.3 0.0 0.084 12.9 0.1 3.3 1 1 2 3 3 3 3 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 KXS20492.1 - 0.00041 19.0 1.4 0.46 9.0 0.0 3.0 1 1 2 3 3 3 3 Adaptin N terminal region Proteasom_PSMB PF10508.9 KXS20492.1 - 0.0014 17.2 0.8 0.011 14.3 0.2 2.1 1 1 0 2 2 2 1 Proteasome non-ATPase 26S subunit RICTOR_N PF14664.6 KXS20492.1 - 0.01 14.9 0.6 1.9 7.4 0.1 2.3 1 1 1 2 2 2 0 Rapamycin-insensitive companion of mTOR, N-term WAPL PF07814.13 KXS20492.1 - 0.022 13.6 7.2 0.2 10.4 1.0 2.4 2 1 0 2 2 2 0 Wings apart-like protein regulation of heterochromatin CLASP_N PF12348.8 KXS20492.1 - 0.076 12.6 0.0 1.2 8.7 0.0 2.4 2 1 1 3 3 3 0 CLASP N terminal IF-2B PF01008.17 KXS20496.1 - 5e-69 232.6 0.0 9.8e-69 231.7 0.0 1.5 1 1 0 1 1 1 1 Initiation factor 2 subunit family BolA PF01722.18 KXS20497.1 - 3.1e-16 59.4 0.0 6.2e-16 58.5 0.0 1.5 1 1 0 1 1 1 1 BolA-like protein CTD_bind PF04818.13 KXS20498.1 - 2.6e-17 63.4 0.6 6.4e-17 62.1 0.1 2.0 2 0 0 2 2 2 1 RNA polymerase II-binding domain. Exonuc_VII_L PF02601.15 KXS20498.1 - 0.0019 17.8 0.1 0.0035 17.0 0.1 1.3 1 0 0 1 1 1 1 Exonuclease VII, large subunit CREPT PF16566.5 KXS20498.1 - 0.0023 18.1 0.0 0.0071 16.5 0.0 1.8 2 0 0 2 2 2 1 Cell-cycle alteration and expression-elevated protein in tumour CTK3 PF12243.8 KXS20498.1 - 0.052 13.6 0.0 0.089 12.8 0.0 1.5 1 0 0 1 1 1 0 CTD kinase subunit gamma CTK3 Spc7 PF08317.11 KXS20498.1 - 0.56 9.0 2.5 1 8.2 2.5 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein SR-25 PF10500.9 KXS20498.1 - 2.8 7.5 7.6 5 6.7 7.6 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RibD_C PF01872.17 KXS20499.1 - 8.4e-33 113.9 0.0 6.2e-32 111.1 0.0 2.0 1 1 0 1 1 1 1 RibD C-terminal domain Cyclase PF04199.13 KXS20500.1 - 3.4e-12 46.8 0.0 4.6e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase Fasciclin PF02469.22 KXS20504.1 - 5.8e-33 113.8 1.5 1.3e-15 57.7 0.3 2.2 2 0 0 2 2 2 2 Fasciclin domain Chitin_bind_1 PF00187.19 KXS20504.1 - 1.3e-12 47.9 45.6 3.5e-06 27.4 18.5 2.4 2 0 0 2 2 2 2 Chitin recognition protein Gar1 PF04410.14 KXS20505.1 - 2.5e-41 141.0 0.0 3e-41 140.8 0.0 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region ATP-synt_10 PF05176.14 KXS20506.1 - 2.5e-31 108.9 0.0 3.6e-31 108.4 0.0 1.1 1 0 0 1 1 1 1 ATP10 protein Fungal_trans PF04082.18 KXS20508.1 - 7.9e-08 31.6 0.0 1.3e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Rhomboid PF01694.22 KXS20509.1 - 8.8e-23 81.0 11.3 1.8e-22 80.0 11.3 1.4 1 0 0 1 1 1 1 Rhomboid family DUF1751 PF08551.10 KXS20509.1 - 0.035 14.7 0.3 0.11 13.0 0.0 1.9 2 0 0 2 2 2 0 Eukaryotic integral membrane protein (DUF1751) Peptidase_M15_3 PF08291.11 KXS20510.1 - 4.4 7.4 5.2 0.78 9.9 0.2 2.4 3 0 0 3 3 3 0 Peptidase M15 Vfa1 PF08432.10 KXS20510.1 - 4.6 7.5 12.6 8.7 6.6 6.9 2.7 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 DnaJ_CXXCXGXG PF00684.19 KXS20514.1 - 0.0015 18.9 0.2 1 9.8 0.3 2.2 2 0 0 2 2 2 2 DnaJ central domain Anti-TRAP PF15777.5 KXS20514.1 - 0.024 14.6 0.5 1.7 8.7 0.1 2.3 2 0 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein SWIRM PF04433.17 KXS20515.1 - 1.8e-08 34.6 0.1 3.8e-08 33.6 0.1 1.5 1 0 0 1 1 1 1 SWIRM domain Abhydrolase_1 PF00561.20 KXS20516.1 - 3.2e-17 63.0 0.2 4.5e-17 62.6 0.2 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXS20516.1 - 5.6e-10 40.2 5.6 1e-09 39.4 5.6 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXS20516.1 - 2.7e-08 33.4 0.1 4.1e-08 32.8 0.1 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.20 KXS20516.1 - 0.0011 18.7 0.1 0.0033 17.1 0.0 1.7 1 1 1 2 2 2 1 Putative esterase PGAP1 PF07819.13 KXS20516.1 - 0.022 14.5 0.0 0.03 14.0 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein LIDHydrolase PF10230.9 KXS20516.1 - 0.12 12.0 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase DUF915 PF06028.11 KXS20516.1 - 0.18 11.1 0.0 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) DSPc PF00782.20 KXS20517.1 - 1.7e-18 66.7 0.0 2.4e-18 66.2 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 KXS20517.1 - 0.0052 16.9 0.0 0.0092 16.1 0.0 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 KXS20517.1 - 0.047 13.3 0.0 0.065 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 KXS20517.1 - 0.059 13.3 0.0 0.091 12.7 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 KXS20517.1 - 0.17 11.4 0.1 0.56 9.8 0.1 1.8 1 1 0 1 1 1 0 Tyrosine phosphatase family Peptidase_M64 PF09471.10 KXS20518.1 - 2.4e-31 109.2 0.0 4.5e-30 105.0 0.0 2.1 1 1 0 1 1 1 1 IgA Peptidase M64 Tubulin PF00091.25 KXS20519.1 - 2.7e-68 230.1 0.0 3.7e-68 229.6 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KXS20519.1 - 8.4e-52 174.6 0.0 1.3e-51 174.0 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KXS20519.1 - 0.00079 19.2 0.0 0.0014 18.4 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain DHC_N1 PF08385.12 KXS20520.1 - 0.097 11.3 0.5 0.14 10.7 0.5 1.2 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 1 FYRC PF05965.14 KXS20521.1 - 1.6e-15 57.1 0.0 1.8e-14 53.7 0.0 2.3 2 0 0 2 2 2 1 F/Y rich C-terminus FYRN PF05964.14 KXS20521.1 - 1.6e-14 53.5 0.1 2.9e-14 52.6 0.1 1.5 1 0 0 1 1 1 1 F/Y-rich N-terminus DUF2380 PF09533.10 KXS20521.1 - 0.15 11.7 0.0 0.31 10.6 0.0 1.4 1 0 0 1 1 1 0 Predicted lipoprotein of unknown function (DUF2380) Vac_Fusion PF02346.16 KXS20521.1 - 0.21 11.3 0.3 0.36 10.5 0.3 1.3 1 0 0 1 1 1 0 Chordopoxvirus multifunctional envelope protein A27 ATG16 PF08614.11 KXS20521.1 - 0.21 11.8 0.6 0.49 10.6 0.6 1.5 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DTHCT PF08070.11 KXS20521.1 - 1.1 10.0 7.3 0.79 10.5 0.2 3.0 2 1 0 2 2 2 0 DTHCT (NUC029) region Lactamase_B_6 PF16661.5 KXS20522.1 - 4.7e-56 189.3 0.0 6.7e-56 188.8 0.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain CPSF100_C PF13299.6 KXS20522.1 - 1.9e-29 103.0 0.1 1.3e-24 87.3 0.0 2.3 1 1 1 2 2 2 2 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.8 KXS20522.1 - 2.3e-13 50.4 0.0 4.4e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.12 KXS20522.1 - 1.7e-08 34.3 0.0 4.5e-08 32.9 0.0 1.7 2 0 0 2 2 2 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 KXS20522.1 - 2.3e-06 27.3 0.1 4.3e-06 26.4 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KXS20522.1 - 5e-05 23.4 1.0 0.00036 20.6 1.0 2.3 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Cyclin PF08613.11 KXS20523.1 - 1.6e-34 119.6 0.0 2e-34 119.3 0.0 1.2 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 KXS20523.1 - 8.5e-07 28.8 0.2 2.3e-06 27.4 0.1 1.6 1 1 1 2 2 2 1 Cyclin, N-terminal domain RRF_GI PF12614.8 KXS20523.1 - 0.038 14.1 0.0 0.25 11.5 0.0 2.1 2 1 0 2 2 2 0 Ribosome recycling factor Gtr1_RagA PF04670.12 KXS20524.1 - 2.5e-63 213.6 0.1 3.3e-63 213.2 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 KXS20524.1 - 4.9e-06 26.1 0.0 7.8e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_16 PF13191.6 KXS20524.1 - 0.001 19.4 0.0 0.0053 17.1 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.23 KXS20524.1 - 0.0025 17.9 0.0 0.0051 16.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 KXS20524.1 - 0.0092 16.2 0.0 0.017 15.3 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KXS20524.1 - 0.013 14.9 0.0 0.026 14.0 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_14 PF13173.6 KXS20524.1 - 0.07 13.2 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain CSN8_PSD8_EIF3K PF10075.9 KXS20525.1 - 1.2e-24 86.9 0.0 1.7e-24 86.5 0.0 1.2 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family UQ_con PF00179.26 KXS20526.1 - 2.7e-46 156.7 0.1 3.1e-46 156.5 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KXS20526.1 - 0.0074 16.0 0.0 0.0082 15.8 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KXS20526.1 - 0.1 12.9 1.8 0.16 12.3 1.7 1.6 1 1 0 1 1 1 0 RWD domain MIP PF00230.20 KXS20527.1 - 2.1e-42 145.4 12.9 4.1e-26 92.1 5.6 2.0 2 0 0 2 2 2 2 Major intrinsic protein Pkinase PF00069.25 KXS20528.1 - 2.4e-69 233.6 0.0 3e-69 233.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS20528.1 - 1.7e-29 102.9 0.0 5.4e-29 101.3 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXS20528.1 - 0.00024 20.5 0.1 0.0062 15.9 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KXS20528.1 - 0.037 12.8 0.0 0.095 11.5 0.0 1.5 2 0 0 2 2 2 0 Fungal protein kinase TIP41 PF04176.13 KXS20529.1 - 2.8e-48 163.6 0.0 4.2e-48 163.1 0.0 1.3 1 0 0 1 1 1 1 TIP41-like family MM_CoA_mutase PF01642.22 KXS20530.1 - 2.7e-237 788.4 0.2 3.2e-237 788.1 0.2 1.0 1 0 0 1 1 1 1 Methylmalonyl-CoA mutase B12-binding PF02310.19 KXS20530.1 - 1.8e-14 53.8 0.9 3.9e-14 52.7 0.9 1.6 1 0 0 1 1 1 1 B12 binding domain HisG_C PF08029.11 KXS20530.1 - 0.11 12.7 0.8 0.36 11.0 0.1 2.2 3 0 0 3 3 3 0 HisG, C-terminal domain Nse4_C PF08743.10 KXS20531.1 - 1.5e-22 79.6 0.0 1.2e-21 76.8 0.0 2.4 2 0 0 2 2 2 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.6 KXS20531.1 - 0.0057 16.7 0.1 0.0057 16.7 0.1 2.1 2 0 0 2 2 2 1 Binding domain of Nse4/EID3 to Nse3-MAGE GREB1 PF15782.5 KXS20531.1 - 4.1 4.4 4.3 5.8 3.9 4.3 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PPR_2 PF13041.6 KXS20532.1 - 7.1e-09 35.7 0.0 0.0021 18.2 0.0 3.4 3 0 0 3 3 3 2 PPR repeat family PPR_long PF17177.4 KXS20532.1 - 2.5e-05 23.7 0.0 0.00011 21.6 0.0 2.0 2 0 0 2 2 2 1 Pentacotripeptide-repeat region of PRORP PPR_3 PF13812.6 KXS20532.1 - 0.031 14.4 0.0 29 4.8 0.0 3.5 4 0 0 4 4 4 0 Pentatricopeptide repeat domain TPR_16 PF13432.6 KXS20532.1 - 3.7 8.3 6.8 7 7.4 0.2 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 KXS20532.1 - 6.7 7.7 6.8 17 6.4 0.0 4.8 6 0 0 6 6 6 0 Tetratricopeptide repeat Spc7 PF08317.11 KXS20533.1 - 0.0083 15.0 2.1 0.0083 15.0 2.1 3.4 1 1 4 5 5 5 1 Spc7 kinetochore protein FlaC_arch PF05377.11 KXS20533.1 - 0.089 13.2 1.0 21 5.6 0.0 3.6 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF445 PF04286.12 KXS20533.1 - 4.1 7.1 9.2 7.3 6.3 1.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF445) adh_short PF00106.25 KXS20534.1 - 2.5e-71 239.2 13.8 2.7e-39 134.7 4.2 2.3 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXS20534.1 - 7.2e-58 195.9 12.2 2.9e-32 112.1 4.8 3.0 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXS20534.1 - 1e-23 84.2 8.5 1.4e-11 44.7 0.7 2.5 2 1 0 2 2 2 2 KR domain THF_DHG_CYH_C PF02882.19 KXS20534.1 - 0.0013 18.1 0.4 0.71 9.2 0.3 2.6 2 0 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 2-Hacid_dh_C PF02826.19 KXS20534.1 - 0.0063 15.9 1.8 0.011 15.1 0.1 2.2 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PglL_A PF15864.5 KXS20534.1 - 0.51 10.1 7.1 3.6 7.4 1.0 2.6 2 0 0 2 2 2 0 Protein glycosylation ligase DUF543 PF04418.12 KXS20534.1 - 1.7 8.7 5.4 4.5 7.3 0.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF543) LRR_4 PF12799.7 KXS20535.1 - 3.5e-16 59.1 15.7 7.1e-09 35.8 0.5 3.4 2 2 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXS20535.1 - 5.6e-10 38.8 11.8 9e-05 22.2 0.3 3.2 1 1 2 3 3 3 3 Leucine rich repeat LRR_1 PF00560.33 KXS20535.1 - 6.8e-06 25.9 18.2 0.86 10.4 0.1 5.5 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_6 PF13516.6 KXS20535.1 - 0.0031 17.4 5.7 0.16 12.1 0.0 3.8 4 0 0 4 4 4 2 Leucine Rich repeat LRR_9 PF14580.6 KXS20535.1 - 0.031 13.8 2.8 0.4 10.2 2.8 2.0 1 1 0 1 1 1 0 Leucine-rich repeat Methyltransf_23 PF13489.6 KXS20536.1 - 4.8e-06 26.5 0.0 6.9e-06 26.0 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXS20536.1 - 0.00037 21.1 0.0 1.2 9.9 0.0 2.4 1 1 1 2 2 2 2 Methyltransferase domain 7tm_1 PF00001.21 KXS20537.1 - 4e-10 39.5 2.3 5e-10 39.1 2.3 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) PRIMA1 PF16101.5 KXS20537.1 - 0.049 13.7 1.2 0.063 13.3 0.0 1.7 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 DUF1644 PF07800.12 KXS20538.1 - 0.016 15.3 0.1 0.045 13.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1644) VIT1 PF01988.19 KXS20538.1 - 0.1 12.5 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 VIT family PEHE PF15275.6 KXS20539.1 - 0.35 11.5 5.1 0.071 13.7 1.1 1.9 2 0 0 2 2 2 0 PEHE domain Guanylate_cyc PF00211.20 KXS20541.1 - 2.4e-19 69.7 0.0 4.6e-19 68.7 0.0 1.4 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain Bac_rhodopsin PF01036.18 KXS20541.1 - 0.0017 18.0 1.1 0.0025 17.4 1.1 1.2 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein LRR_4 PF12799.7 KXS20542.1 - 0.75 10.3 12.1 2.4 8.7 1.2 5.2 5 1 1 6 6 6 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KXS20542.1 - 2.8 8.2 10.3 75 3.8 0.0 6.0 7 0 0 7 7 7 0 Leucine Rich repeat CRAL_TRIO PF00650.20 KXS20543.1 - 3.7e-17 62.5 0.0 6.1e-17 61.8 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain AAA_2 PF07724.14 KXS20544.1 - 8.4e-55 185.5 0.0 2.3e-51 174.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 KXS20544.1 - 2.4e-34 117.4 0.3 2.4e-34 117.4 0.3 2.5 1 1 1 2 2 2 1 AAA lid domain ClpB_D2-small PF10431.9 KXS20544.1 - 1.1e-26 92.7 0.4 4e-26 90.9 0.4 2.1 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 KXS20544.1 - 1.3e-23 83.8 0.0 3.2e-11 43.8 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KXS20544.1 - 2.2e-17 63.3 0.0 1.1e-11 44.9 0.0 3.2 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 KXS20544.1 - 1.9e-12 47.2 0.2 5.5e-08 32.7 0.0 2.8 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_16 PF13191.6 KXS20544.1 - 1.7e-08 35.0 12.4 0.00018 21.9 0.1 5.0 3 2 1 4 4 4 2 AAA ATPase domain AAA_22 PF13401.6 KXS20544.1 - 7e-08 32.8 3.5 0.014 15.6 0.1 4.7 2 2 1 3 3 3 2 AAA domain IstB_IS21 PF01695.17 KXS20544.1 - 2.9e-07 30.4 0.0 0.038 13.7 0.0 2.8 2 0 0 2 2 2 2 IstB-like ATP binding protein TniB PF05621.11 KXS20544.1 - 1.6e-05 24.4 0.0 0.027 13.9 0.0 3.8 3 1 0 3 3 3 1 Bacterial TniB protein AAA_7 PF12775.7 KXS20544.1 - 2.2e-05 24.1 0.0 0.044 13.3 0.0 2.7 2 0 0 2 2 2 2 P-loop containing dynein motor region NACHT PF05729.12 KXS20544.1 - 3e-05 24.0 0.3 0.0072 16.3 0.0 3.2 4 0 0 4 4 2 1 NACHT domain Mg_chelatase PF01078.21 KXS20544.1 - 3.5e-05 23.3 0.6 0.53 9.6 0.0 3.6 3 1 0 3 3 3 1 Magnesium chelatase, subunit ChlI ATPase_2 PF01637.18 KXS20544.1 - 7e-05 22.9 1.0 1.6 8.6 0.4 3.7 2 2 0 3 3 2 1 ATPase domain predominantly from Archaea RuvB_N PF05496.12 KXS20544.1 - 0.00012 21.9 1.3 1.3 8.8 0.0 4.1 3 1 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 KXS20544.1 - 0.00013 22.0 0.0 0.21 11.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 KXS20544.1 - 0.00014 22.3 0.1 1.2 9.5 0.0 3.6 4 0 0 4 4 3 2 RNA helicase TsaE PF02367.17 KXS20544.1 - 0.00016 21.7 0.0 0.31 11.0 0.0 2.6 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Roc PF08477.13 KXS20544.1 - 0.00021 21.5 0.2 0.52 10.5 0.0 3.0 4 0 0 4 4 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 KXS20544.1 - 0.00021 21.1 0.0 0.2 11.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KXS20544.1 - 0.00031 21.3 0.0 0.26 11.9 0.0 3.0 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 KXS20544.1 - 0.00056 20.0 0.0 2.5 8.1 0.0 3.0 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit ABC_tran PF00005.27 KXS20544.1 - 0.0011 19.5 0.0 0.23 11.9 0.0 2.8 2 0 0 2 2 2 1 ABC transporter AAA_23 PF13476.6 KXS20544.1 - 0.0035 17.9 7.9 3.1 8.2 0.1 3.6 3 1 0 3 3 3 1 AAA domain TIP49 PF06068.13 KXS20544.1 - 0.0043 16.3 0.2 2.1 7.4 0.0 2.7 2 0 0 2 2 2 1 TIP49 P-loop domain Bac_DnaA PF00308.18 KXS20544.1 - 0.0044 16.9 0.0 3.1 7.6 0.0 2.6 2 0 0 2 2 2 1 Bacterial dnaA protein RsgA_GTPase PF03193.16 KXS20544.1 - 0.0045 16.9 0.0 3.1 7.7 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase DNA_pol3_delta2 PF13177.6 KXS20544.1 - 0.0062 16.3 0.0 6.9 6.4 0.0 3.3 4 0 0 4 4 3 0 DNA polymerase III, delta subunit AAA_19 PF13245.6 KXS20544.1 - 0.0068 16.7 0.0 0.65 10.3 0.0 3.2 3 0 0 3 3 3 1 AAA domain DUF99 PF01949.16 KXS20544.1 - 0.0092 15.4 0.1 2.8 7.3 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function DUF99 PduV-EutP PF10662.9 KXS20544.1 - 0.021 14.6 0.0 0.68 9.7 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NTPase_1 PF03266.15 KXS20544.1 - 0.03 14.2 0.0 6.1 6.7 0.0 3.0 2 0 0 2 2 2 0 NTPase Zeta_toxin PF06414.12 KXS20544.1 - 0.031 13.6 0.0 2.2 7.5 0.0 3.0 3 0 0 3 3 3 0 Zeta toxin NB-ARC PF00931.22 KXS20544.1 - 0.036 13.2 0.0 1.6 7.8 0.0 2.7 2 0 0 2 2 2 0 NB-ARC domain Ribosomal_S7 PF00177.21 KXS20544.1 - 0.04 13.6 1.1 0.45 10.2 0.1 2.8 3 0 0 3 3 3 0 Ribosomal protein S7p/S5e PhoH PF02562.16 KXS20544.1 - 0.047 13.1 0.0 1.7 8.1 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein DUF4349 PF14257.6 KXS20544.1 - 0.047 13.1 5.2 0.16 11.4 5.2 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) AAA_25 PF13481.6 KXS20544.1 - 0.063 12.8 3.5 0.44 10.1 0.0 3.6 4 1 0 4 4 4 0 AAA domain AAA_29 PF13555.6 KXS20544.1 - 0.074 12.8 0.0 10 5.9 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain ATP_bind_1 PF03029.17 KXS20544.1 - 0.084 12.6 0.0 1.2 8.8 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_3 PF07726.11 KXS20544.1 - 0.12 12.2 0.0 2 8.3 0.0 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 KXS20544.1 - 0.14 12.4 1.1 23 5.2 0.0 3.6 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.17 KXS20544.1 - 0.19 11.8 0.9 15 5.5 0.0 3.1 3 0 0 3 3 3 0 Helicase HerA, central domain ADIP PF11559.8 KXS20544.1 - 2.8 8.0 8.0 6.1 6.9 8.0 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF2236 PF09995.9 KXS20545.1 - 1.2e-07 32.1 0.2 1.2e-06 28.9 0.3 2.1 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2236) Hemerythrin PF01814.23 KXS20546.1 - 6e-09 36.6 1.4 7.5e-09 36.3 0.3 1.7 2 0 0 2 2 2 1 Hemerythrin HHE cation binding domain GST_N_3 PF13417.6 KXS20546.1 - 1.1e-05 25.7 0.0 3.7e-05 24.0 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KXS20546.1 - 0.00055 20.2 0.0 0.0022 18.3 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain FANCI_S3 PF14677.6 KXS20546.1 - 0.05 13.3 1.2 0.079 12.7 1.2 1.3 1 0 0 1 1 1 0 FANCI solenoid 3 zf-4CXXC_R1 PF10497.9 KXS20547.1 - 1.5e-32 111.7 8.0 2.1e-32 111.3 8.0 1.2 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 PHD_4 PF16866.5 KXS20547.1 - 1.9 8.6 9.1 0.29 11.2 4.2 2.1 2 0 0 2 2 2 0 PHD-finger Cyt-b5 PF00173.28 KXS20548.1 - 2.3e-11 43.7 0.1 3.9e-11 42.9 0.1 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain G6PD_C PF02781.16 KXS20549.1 - 1.4e-112 375.6 0.0 2.3e-112 374.9 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 KXS20549.1 - 2.7e-61 207.3 0.1 5.6e-61 206.3 0.1 1.5 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain GHMP_kinases_N PF00288.26 KXS20550.1 - 1.7e-13 50.5 0.7 3.5e-13 49.6 0.7 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KXS20550.1 - 0.027 14.8 0.0 0.056 13.8 0.0 1.5 1 0 0 1 1 1 0 GHMP kinases C terminal PAP1 PF08601.10 KXS20550.1 - 0.48 10.1 4.3 0.8 9.4 4.3 1.3 1 0 0 1 1 1 0 Transcription factor PAP1 FAD_binding_1 PF00667.20 KXS20551.1 - 8.1e-40 136.7 0.0 1.6e-39 135.8 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KXS20551.1 - 1e-27 97.1 0.5 2e-27 96.1 0.5 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 KXS20551.1 - 6.1e-16 59.0 0.0 2e-14 54.2 0.0 2.5 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain Glyco_tran_WecB PF03808.13 KXS20551.1 - 0.15 12.0 0.1 1.9 8.4 0.0 2.5 3 0 0 3 3 3 0 Glycosyl transferase WecB/TagA/CpsF family PRAP PF15314.6 KXS20551.1 - 0.17 12.3 0.9 0.92 10.0 0.3 2.4 2 0 0 2 2 2 0 Proline-rich acidic protein 1, pregnancy-specific uterine DUF1180 PF06679.12 KXS20551.1 - 0.17 12.3 0.7 0.32 11.4 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Peptidase_M20 PF01546.28 KXS20552.1 - 7.6e-30 104.2 0.1 1e-29 103.8 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KXS20552.1 - 5.8e-11 42.3 0.0 1e-10 41.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KXS20552.1 - 0.00038 20.2 0.0 0.0014 18.4 0.0 1.8 2 0 0 2 2 2 1 Peptidase family M28 2OG-FeII_Oxy_2 PF13532.6 KXS20553.1 - 0.019 15.2 0.0 0.098 12.8 0.0 2.1 2 1 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily Surface_antigen PF11054.8 KXS20553.1 - 0.095 12.4 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Sporozoite TA4 surface antigen Ank_3 PF13606.6 KXS20554.1 - 5.5e-13 47.8 11.6 0.0051 17.2 0.0 10.0 10 0 0 10 10 10 3 Ankyrin repeat Ank_2 PF12796.7 KXS20554.1 - 1.1e-12 48.3 3.5 0.00079 20.0 0.0 7.3 7 2 0 7 7 7 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXS20554.1 - 7.8e-10 39.1 2.3 5.6 7.7 0.0 8.0 8 0 0 8 8 8 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXS20554.1 - 3.5e-08 33.6 3.7 0.09 13.1 0.0 7.6 8 0 0 8 8 8 2 Ankyrin repeats (many copies) Ank PF00023.30 KXS20554.1 - 1.2e-06 28.7 15.0 0.049 14.1 0.0 8.1 9 0 0 9 9 9 2 Ankyrin repeat DUF3447 PF11929.8 KXS20554.1 - 0.11 12.5 0.2 5.6 7.0 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3447) Sec2p PF06428.11 KXS20554.1 - 0.25 11.3 7.5 0.17 11.9 2.8 2.5 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p SlyX PF04102.12 KXS20554.1 - 0.41 11.3 11.8 1.1 9.9 0.5 3.6 1 1 1 2 2 2 0 SlyX MPS2 PF17060.5 KXS20554.1 - 5 6.3 6.4 19 4.4 0.5 2.2 1 1 1 2 2 2 0 Monopolar spindle protein 2 PepX_C PF08530.10 KXS20556.1 - 2.8e-28 99.4 0.1 3.6e-28 99.0 0.1 1.1 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Peptidase_S15 PF02129.18 KXS20556.1 - 6.2e-11 42.4 0.2 9.2e-11 41.8 0.2 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) P34-Arc PF04045.14 KXS20557.1 - 2.5e-104 348.2 0.0 3e-104 348.0 0.0 1.0 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc Arf PF00025.21 KXS20558.1 - 1.5e-80 268.7 0.2 1.8e-80 268.5 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KXS20558.1 - 3.5e-14 53.0 0.0 5.1e-14 52.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KXS20558.1 - 1.7e-13 50.4 0.0 2.1e-13 50.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KXS20558.1 - 7e-13 48.5 1.3 6.2e-09 35.5 0.2 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 KXS20558.1 - 7.2e-13 48.5 0.0 7.8e-13 48.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KXS20558.1 - 4.1e-10 39.4 0.0 4.9e-10 39.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KXS20558.1 - 8.5e-06 25.8 0.0 1.3e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 KXS20558.1 - 0.0087 15.4 0.3 0.028 13.7 0.1 1.7 2 0 0 2 2 2 1 6-phosphofructo-2-kinase WD40 PF00400.32 KXS20559.1 - 9.8e-20 70.5 7.4 6.1e-05 23.7 0.1 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXS20559.1 - 1.4e-10 41.3 0.0 0.18 12.1 0.0 5.0 2 2 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Mpv17_PMP22 PF04117.12 KXS20560.1 - 2e-17 63.2 0.3 2e-17 63.2 0.3 1.7 2 0 0 2 2 2 1 Mpv17 / PMP22 family WD40 PF00400.32 KXS20561.1 - 6.1e-47 156.6 8.5 2.5e-06 28.1 0.4 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXS20561.1 - 5.9e-10 39.3 0.3 0.089 13.1 0.0 5.0 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain F-box-like PF12937.7 KXS20561.1 - 5.7e-07 29.3 0.1 1.4e-06 28.1 0.1 1.6 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.8 KXS20561.1 - 7.3e-05 21.6 4.6 0.23 10.1 0.1 4.5 3 2 0 5 5 5 2 Nucleoporin Nup120/160 F-box PF00646.33 KXS20561.1 - 8e-05 22.4 0.9 0.0002 21.2 0.0 1.9 2 0 0 2 2 2 1 F-box domain PQQ_3 PF13570.6 KXS20561.1 - 0.1 13.1 1.2 57 4.4 0.2 4.0 3 0 0 3 3 3 0 PQQ-like domain Smg8_Smg9 PF10220.9 KXS20562.1 - 0.31 9.3 0.0 0.45 8.8 0.0 1.1 1 0 0 1 1 1 0 Smg8_Smg9 IBR PF01485.21 KXS20563.1 - 2.7e-08 33.9 11.8 2.7e-08 33.9 11.8 2.0 2 0 0 2 2 2 1 IBR domain, a half RING-finger domain zf-C2H2 PF00096.26 KXS20563.1 - 0.023 15.2 0.2 0.023 15.2 0.2 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-ANAPC11 PF12861.7 KXS20563.1 - 0.029 14.4 7.4 0.58 10.3 6.1 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C2H2_4 PF13894.6 KXS20563.1 - 0.056 14.3 0.1 0.056 14.3 0.1 4.3 3 1 1 4 4 4 0 C2H2-type zinc finger zf-C2HC_2 PF13913.6 KXS20563.1 - 0.38 10.7 0.0 0.38 10.7 0.0 3.7 3 1 1 4 4 4 0 zinc-finger of a C2HC-type zf-Di19 PF05605.12 KXS20563.1 - 3.7 7.9 10.6 1.1 9.6 0.2 2.7 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Cript PF10235.9 KXS20563.1 - 8.2 7.1 10.5 20 5.8 8.5 2.2 2 0 0 2 2 2 0 Microtubule-associated protein CRIPT Polyketide_cyc PF03364.20 KXS20564.1 - 5e-15 55.9 0.0 6.9e-15 55.4 0.0 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport NTF2 PF02136.20 KXS20565.1 - 0.029 14.9 0.0 0.081 13.5 0.0 1.6 2 0 0 2 2 2 0 Nuclear transport factor 2 (NTF2) domain DUF3040 PF11239.8 KXS20565.1 - 0.032 14.5 1.0 0.079 13.2 1.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) Casein_kappa PF00997.18 KXS20565.1 - 2.8 8.0 6.9 6.3 6.9 6.9 1.5 1 0 0 1 1 1 0 Kappa casein Glyco_hydro_26 PF02156.15 KXS20566.1 - 0.014 14.8 14.4 0.035 13.5 7.9 2.6 2 1 0 2 2 2 0 Glycosyl hydrolase family 26 EF-hand_5 PF13202.6 KXS20566.1 - 0.026 14.0 0.0 0.053 13.0 0.0 1.5 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.6 KXS20566.1 - 0.13 12.2 0.1 0.32 11.0 0.1 1.6 1 0 0 1 1 1 0 EF-hand domain EF-hand_1 PF00036.32 KXS20566.1 - 0.29 10.8 0.6 0.56 9.9 0.1 1.8 2 0 0 2 2 2 0 EF hand ApbA PF02558.16 KXS20567.1 - 2e-18 66.5 0.0 4.2e-18 65.4 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 KXS20567.1 - 6.9e-14 52.1 0.0 1.1e-13 51.5 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal THF_DHG_CYH PF00763.23 KXS20568.1 - 4.3e-26 91.5 0.0 8.7e-26 90.5 0.0 1.5 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 KXS20568.1 - 8.6e-16 57.7 0.1 1.8e-09 37.1 0.0 3.0 2 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain SBP_bac_5 PF00496.22 KXS20568.1 - 0.022 13.7 0.0 0.031 13.3 0.0 1.1 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 5 Middle UDPG_MGDP_dh_N PF03721.14 KXS20568.1 - 0.025 14.1 0.2 0.59 9.7 0.2 2.3 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Fasciclin PF02469.22 KXS20569.1 - 7.2e-05 23.0 0.0 0.00011 22.4 0.0 1.2 1 0 0 1 1 1 1 Fasciclin domain Pkinase PF00069.25 KXS20570.1 - 8e-51 172.9 0.0 2.2e-33 115.8 0.0 2.3 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXS20570.1 - 4.8e-22 78.5 0.0 5.4e-18 65.2 0.0 2.5 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KXS20570.1 - 0.0041 16.5 0.0 0.007 15.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KXS20570.1 - 0.018 13.8 0.0 0.026 13.3 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 KXS20570.1 - 0.028 13.8 0.0 0.044 13.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXS20570.1 - 0.068 13.1 0.1 0.2 11.5 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Lysine_decarbox PF03641.14 KXS20571.1 - 6.6e-38 129.8 0.1 8.3e-38 129.5 0.1 1.1 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 KXS20571.1 - 9.6e-15 54.5 0.0 1.2e-14 54.2 0.0 1.2 1 0 0 1 1 1 1 SLOG cluster4 family DUF5559 PF17714.1 KXS20572.1 - 0.18 11.7 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5559) DnaJ PF00226.31 KXS20573.1 - 1.3e-12 47.7 1.2 3.1e-12 46.4 1.2 1.8 1 0 0 1 1 1 1 DnaJ domain Croc_4 PF17691.1 KXS20573.1 - 0.091 12.8 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 Contingent replication of cDNA 4 APC_u5 PF16630.5 KXS20573.1 - 0.96 10.5 0.0 0.96 10.5 0.0 2.6 2 1 1 3 3 3 0 Unstructured region on APC between 1st and 2nd catenin-bdg motifs Methyltransf_25 PF13649.6 KXS20574.1 - 1.5e-12 48.1 0.0 1.3e-08 35.4 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 KXS20574.1 - 4.1e-12 46.2 0.0 8.1e-12 45.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXS20574.1 - 9.8e-12 45.5 0.0 2.9e-11 44.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXS20574.1 - 7.8e-10 39.3 0.0 3.3e-08 34.0 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXS20574.1 - 3.4e-07 30.2 0.0 1.1e-06 28.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXS20574.1 - 0.034 13.5 0.0 0.052 12.9 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family NNMT_PNMT_TEMT PF01234.17 KXS20574.1 - 0.21 10.7 0.0 0.33 10.1 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family CheR PF01739.18 KXS20574.1 - 0.21 11.0 0.0 0.95 8.9 0.0 1.9 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain Fasciclin PF02469.22 KXS20575.1 - 9.6e-18 64.6 0.0 9.4e-12 45.3 0.0 2.5 2 0 0 2 2 2 2 Fasciclin domain DPM3 PF08285.11 KXS20576.1 - 0.23 11.7 3.6 14 6.0 0.2 3.0 3 0 0 3 3 3 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Pro_CA PF00484.19 KXS20577.1 - 2.6e-48 164.3 0.2 3.1e-48 164.0 0.2 1.1 1 0 0 1 1 1 1 Carbonic anhydrase zf-RING_2 PF13639.6 KXS20578.1 - 3.3e-13 49.7 5.5 4.9e-13 49.2 5.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KXS20578.1 - 9.7e-10 38.1 4.2 1.5e-09 37.5 4.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KXS20578.1 - 1.3e-09 37.6 2.1 2.6e-09 36.6 2.1 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 KXS20578.1 - 6.2e-08 32.4 2.9 9.5e-08 31.8 2.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KXS20578.1 - 2e-06 28.0 7.1 6.2e-06 26.4 7.1 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KXS20578.1 - 3.1e-06 27.0 2.2 4.7e-06 26.5 2.2 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KXS20578.1 - 4.9e-06 26.5 2.6 1.3e-05 25.1 2.8 1.6 1 1 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 KXS20578.1 - 3.9e-05 23.6 0.8 7.8e-05 22.6 0.8 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 KXS20578.1 - 0.00012 21.9 2.1 0.00017 21.4 2.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KXS20578.1 - 0.0006 19.9 4.3 0.0011 19.0 4.3 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Zn_ribbon_17 PF17120.5 KXS20578.1 - 0.0068 16.0 1.1 0.0068 16.0 1.1 1.9 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 KXS20578.1 - 0.01 15.7 6.0 0.22 11.4 6.5 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 KXS20578.1 - 0.042 13.6 3.0 0.069 12.9 3.0 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING-like PF08746.11 KXS20578.1 - 0.21 11.9 2.1 0.37 11.1 2.1 1.4 1 0 0 1 1 1 0 RING-like domain FANCL_C PF11793.8 KXS20578.1 - 0.24 11.6 4.5 1.4 9.1 4.5 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain Mito_carr PF00153.27 KXS20579.1 - 3.4e-55 184.0 2.3 2e-18 66.1 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein CCDC85 PF10226.9 KXS20580.1 - 2.3e-06 27.5 5.3 0.0075 16.0 0.3 2.5 1 1 1 2 2 2 2 CCDC85 family Ank_2 PF12796.7 KXS20580.1 - 3.4e-06 27.5 0.0 0.013 16.0 0.0 2.7 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KXS20580.1 - 0.0016 18.8 0.0 4.4 7.9 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 KXS20580.1 - 0.0035 17.7 0.0 14 6.6 0.0 3.6 3 1 1 4 4 4 1 Ankyrin repeat Rootletin PF15035.6 KXS20580.1 - 0.02 14.9 5.1 0.033 14.2 5.1 1.2 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Ank_4 PF13637.6 KXS20580.1 - 0.033 14.8 0.0 18 6.0 0.0 3.0 2 0 0 2 2 2 0 Ankyrin repeats (many copies) FNIP_M PF14637.6 KXS20580.1 - 0.034 14.2 0.6 0.056 13.4 0.6 1.3 1 0 0 1 1 1 0 Folliculin-interacting protein middle domain APG17 PF04108.12 KXS20580.1 - 0.098 11.7 3.8 0.16 11.0 3.8 1.2 1 0 0 1 1 1 0 Autophagy protein Apg17 DUF4618 PF15397.6 KXS20580.1 - 0.12 11.8 5.5 0.18 11.2 5.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) YabA PF06156.13 KXS20580.1 - 0.19 12.4 2.7 0.42 11.3 2.7 1.5 1 0 0 1 1 1 0 Initiation control protein YabA APC_N_CC PF16689.5 KXS20580.1 - 0.34 11.0 7.1 0.074 13.1 3.7 1.7 2 0 0 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain TMEM171 PF15471.6 KXS20580.1 - 5.3 5.9 7.0 8.9 5.2 7.0 1.3 1 0 0 1 1 1 0 Transmembrane protein family 171 ubiquitin PF00240.23 KXS20582.1 - 4.2e-19 68.1 0.4 4.4e-19 68.0 0.4 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KXS20582.1 - 2.6e-08 33.5 0.1 3e-08 33.3 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 KXS20582.1 - 0.0012 18.7 0.1 0.0013 18.6 0.1 1.1 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_4 PF18036.1 KXS20582.1 - 0.063 13.3 0.4 3.2 7.9 0.0 2.0 1 1 1 2 2 2 0 Ubiquitin-like domain Ubiquitin_5 PF18037.1 KXS20582.1 - 0.07 13.5 0.2 0.071 13.5 0.2 1.1 1 0 0 1 1 1 0 Ubiquitin-like domain Ubiquitin_2 PF14560.6 KXS20582.1 - 0.073 13.5 0.1 0.54 10.8 0.1 1.9 1 1 0 1 1 1 0 Ubiquitin-like domain DUF2407 PF10302.9 KXS20582.1 - 0.078 13.5 0.2 0.081 13.5 0.2 1.1 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 KXS20582.1 - 0.15 12.2 0.1 0.24 11.5 0.1 1.5 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Abhydrolase_3 PF07859.13 KXS20583.1 - 1.4e-26 93.6 0.0 2.2e-22 80.0 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KXS20583.1 - 4.9e-14 52.0 0.0 8e-14 51.3 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Ank_3 PF13606.6 KXS20584.1 - 0.00054 20.2 0.9 0.02 15.4 0.1 3.4 4 0 0 4 4 4 1 Ankyrin repeat Ank PF00023.30 KXS20584.1 - 0.0042 17.5 0.9 0.18 12.3 0.2 3.1 2 1 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 KXS20584.1 - 0.043 14.4 0.1 7 7.4 0.0 2.8 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXS20584.1 - 0.079 13.6 0.1 1.2 9.8 0.0 2.5 2 1 0 2 2 2 0 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXS20584.1 - 0.13 12.6 0.0 1.3 9.5 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeats (many copies) CarboxypepD_reg PF13620.6 KXS20584.1 - 0.15 12.4 0.1 0.26 11.6 0.1 1.4 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain F-box-like PF12937.7 KXS20585.1 - 0.00093 19.0 0.4 0.017 15.0 0.1 2.6 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KXS20585.1 - 0.0091 15.9 0.0 0.028 14.3 0.0 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KXS20586.1 - 2.5e-06 27.3 1.9 5.9e-06 26.1 1.9 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXS20586.1 - 0.031 14.2 5.1 0.031 14.2 5.1 1.8 2 0 0 2 2 2 0 F-box domain Novirhabdo_Nv PF05554.11 KXS20586.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Viral hemorrhagic septicemia virus non-virion protein MFS_1 PF07690.16 KXS20588.1 - 2.2e-41 142.0 46.9 2.2e-41 142.0 46.9 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXS20588.1 - 3.8e-07 29.3 7.8 3.8e-07 29.3 7.8 2.8 2 1 1 3 3 3 2 Sugar (and other) transporter LRR_4 PF12799.7 KXS20589.1 - 9.7e-24 83.1 3.3 9e-06 25.9 0.0 3.5 2 1 3 5 5 5 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KXS20589.1 - 5.4e-12 45.6 0.1 1e-10 41.4 0.1 2.1 1 1 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 KXS20589.1 - 3.6e-10 39.5 1.0 0.00052 19.7 0.3 3.3 2 1 0 2 2 2 2 Leucine rich repeat LRR_1 PF00560.33 KXS20589.1 - 0.0053 17.1 0.6 46 5.1 0.0 4.0 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_6 PF13516.6 KXS20589.1 - 0.15 12.2 0.2 81 3.7 0.0 3.7 4 0 0 4 4 4 0 Leucine Rich repeat zf-C3HC4_3 PF13920.6 KXS20590.1 - 6.3e-14 51.6 5.9 9.1e-14 51.1 5.9 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KXS20590.1 - 1.1e-08 34.7 7.4 2.2e-08 33.8 7.4 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KXS20590.1 - 2.6e-05 24.0 6.7 3.9e-05 23.4 6.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXS20590.1 - 4.7e-05 23.6 6.5 7.2e-05 23.0 6.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KXS20590.1 - 0.00019 21.3 6.6 0.0003 20.7 6.6 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KXS20590.1 - 0.0055 16.5 7.0 0.0086 15.9 7.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-P11 PF03854.14 KXS20590.1 - 0.15 11.8 2.7 0.24 11.1 2.7 1.3 1 0 0 1 1 1 0 P-11 zinc finger UBA_2 PF08587.11 KXS20590.1 - 0.23 11.6 0.0 1.4 9.1 0.0 2.1 2 0 0 2 2 2 0 Ubiquitin associated domain (UBA) zf-RING_UBOX PF13445.6 KXS20590.1 - 0.52 10.4 4.3 0.47 10.5 2.0 2.1 1 1 1 2 2 2 0 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KXS20590.1 - 7.6 6.8 6.9 16 5.7 6.9 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Mito_carr PF00153.27 KXS20592.1 - 1.7e-49 165.7 6.5 3.8e-18 65.2 0.1 4.6 4 1 0 4 4 4 4 Mitochondrial carrier protein RTX PF02382.15 KXS20592.1 - 8.8 5.9 9.6 24 4.5 9.6 1.7 1 0 0 1 1 1 0 N-terminal domain in RTX protein GATase_4 PF13230.6 KXS20594.1 - 8.6e-23 80.6 0.0 1.1e-16 60.5 0.1 3.1 2 1 0 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.6 KXS20594.1 - 9e-11 42.1 0.0 8.5e-10 38.9 0.0 2.3 1 1 0 1 1 1 1 Glutamine amidotransferase domain Abhydrolase_3 PF07859.13 KXS20595.1 - 7.8e-31 107.6 0.0 1.7e-30 106.5 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold FeS_assembly_P PF01883.19 KXS20595.1 - 0.18 12.0 0.6 0.37 11.0 0.6 1.5 1 0 0 1 1 1 0 Iron-sulfur cluster assembly protein COesterase PF00135.28 KXS20595.1 - 0.2 10.5 0.0 0.3 9.9 0.0 1.1 1 0 0 1 1 1 0 Carboxylesterase family RNA_capsid PF03035.14 KXS20595.1 - 1.1 9.2 5.8 0.18 11.8 2.1 1.5 2 0 0 2 2 2 0 Calicivirus putative RNA polymerase/capsid protein LAMTOR PF15454.6 KXS20596.1 - 7e-08 33.0 0.3 1.2e-07 32.2 0.3 1.4 1 0 0 1 1 1 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator CBP4 PF07960.11 KXS20598.1 - 1.2 9.0 2.7 1.7 8.5 2.7 1.2 1 0 0 1 1 1 0 CBP4 Abhydrolase_1 PF00561.20 KXS20599.1 - 1.9e-19 70.3 0.0 7.4e-14 52.0 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXS20599.1 - 4.4e-17 63.4 0.0 5.5e-17 63.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXS20599.1 - 1.1e-09 37.9 0.0 1.9e-09 37.1 0.0 1.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 KXS20599.1 - 7.8e-08 31.4 0.0 9.4e-08 31.1 0.0 1.1 1 0 0 1 1 1 1 Ndr family Abhydrolase_2 PF02230.16 KXS20599.1 - 5.8e-05 23.0 0.0 0.0015 18.4 0.0 2.6 2 1 1 3 3 3 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 KXS20599.1 - 0.00068 19.2 0.1 0.34 10.3 0.0 2.6 1 1 1 2 2 2 2 Prolyl oligopeptidase family Esterase PF00756.20 KXS20599.1 - 0.022 14.4 0.0 0.027 14.1 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Ser_hydrolase PF06821.13 KXS20599.1 - 0.026 14.4 0.1 0.48 10.3 0.0 2.1 2 0 0 2 2 2 0 Serine hydrolase BAAT_C PF08840.11 KXS20599.1 - 0.03 14.3 0.0 0.062 13.2 0.0 1.4 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_5 PF12695.7 KXS20599.1 - 0.043 13.6 0.0 2.5 7.9 0.0 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase family AXE1 PF05448.12 KXS20599.1 - 0.059 12.0 0.0 3.8 6.1 0.0 2.7 1 1 1 3 3 3 0 Acetyl xylan esterase (AXE1) DLH PF01738.18 KXS20599.1 - 0.082 12.5 0.0 0.71 9.4 0.0 2.1 1 1 0 2 2 2 0 Dienelactone hydrolase family MOZ_SAS PF01853.18 KXS20600.1 - 1.4e-74 249.7 0.0 1.8e-74 249.3 0.0 1.1 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 KXS20600.1 - 3e-24 84.4 0.9 5.2e-24 83.6 0.9 1.4 1 0 0 1 1 1 1 MYST family zinc finger domain Acetyltransf_7 PF13508.7 KXS20600.1 - 0.0047 17.3 0.0 0.013 15.9 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain ThuA PF06283.11 KXS20602.1 - 1.6e-22 80.8 0.1 3.3e-12 47.1 0.0 2.4 2 1 0 2 2 2 2 Trehalose utilisation Aldo_ket_red PF00248.21 KXS20603.1 - 7.2e-71 238.8 0.1 8.3e-71 238.6 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF5121 PF17165.4 KXS20603.1 - 0.1 13.1 0.2 0.45 11.0 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5121) DUF4078 PF13300.6 KXS20605.1 - 5.1e-14 52.3 13.8 5.1e-14 52.3 13.8 2.4 1 1 1 2 2 2 1 Domain of unknown function (DUF4078) SelB-wing_3 PF09107.11 KXS20605.1 - 0.035 13.7 0.6 9.2 6.0 0.1 2.7 2 0 0 2 2 2 0 Elongation factor SelB, winged helix DUF3435 PF11917.8 KXS20605.1 - 5.4 5.8 8.3 9.4 5.0 8.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) NBP1 PF08537.10 KXS20605.1 - 5.8 6.2 8.4 10 5.4 8.4 1.2 1 0 0 1 1 1 0 Fungal Nap binding protein NBP1 Peptidase_M19 PF01244.21 KXS20606.1 - 8.5e-104 347.1 0.0 1e-103 346.9 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) IFN-gamma PF00714.17 KXS20607.1 - 0.064 13.1 0.0 0.14 12.0 0.0 1.6 1 1 0 1 1 1 0 Interferon gamma Fn3-like PF14310.6 KXS20608.1 - 0.089 12.9 0.4 1.3 9.2 0.1 2.5 2 0 0 2 2 2 0 Fibronectin type III-like domain Ribosomal_S14 PF00253.21 KXS20610.1 - 3.8e-17 61.8 0.1 1e-16 60.4 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein S14p/S29e WD40 PF00400.32 KXS20611.1 - 0.043 14.7 1.0 23 6.1 0.0 4.5 4 0 0 4 4 4 0 WD domain, G-beta repeat HDV_ag PF01517.18 KXS20611.1 - 0.13 12.1 1.9 0.24 11.2 1.9 1.3 1 0 0 1 1 1 0 Hepatitis delta virus delta antigen PHD PF00628.29 KXS20612.1 - 2.2e-09 37.0 5.2 4.3e-09 36.1 5.2 1.5 1 0 0 1 1 1 1 PHD-finger zf-CpG_bind_C PF12269.8 KXS20612.1 - 2.5e-05 24.2 0.0 6.2e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 CpG binding protein zinc finger C terminal domain Zf_RING PF16744.5 KXS20612.1 - 0.76 9.9 5.3 0.59 10.3 3.0 2.0 2 0 0 2 2 2 0 KIAA1045 RING finger NTP_transf_9 PF04248.12 KXS20614.1 - 1e-33 115.0 0.3 1.5e-33 114.5 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF427) Nuc_sug_transp PF04142.15 KXS20615.1 - 1.1e-55 189.1 3.3 1.6e-55 188.5 3.3 1.2 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 KXS20615.1 - 1.5e-06 28.4 17.8 0.0003 21.0 2.9 2.2 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 KXS20615.1 - 0.00015 21.0 3.0 0.0007 18.9 3.0 2.0 1 1 0 1 1 1 1 UAA transporter family PUNUT PF16913.5 KXS20615.1 - 0.0027 17.0 7.4 0.016 14.5 3.4 2.2 2 0 0 2 2 2 2 Purine nucleobase transmembrane transport EmrE PF13536.6 KXS20615.1 - 0.014 15.0 2.9 0.015 14.9 0.3 2.0 2 0 0 2 2 2 0 Putative multidrug resistance efflux transporter BioY PF02632.14 KXS20616.1 - 2.4e-34 118.3 17.8 2.4e-34 118.3 17.8 1.4 2 0 0 2 2 2 1 BioY family MetJ PF01340.20 KXS20616.1 - 0.23 11.5 0.0 0.38 10.8 0.0 1.3 1 0 0 1 1 1 0 Met Apo-repressor, MetJ Fungal_trans PF04082.18 KXS20617.1 - 6.1e-11 41.8 0.0 1.3e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXS20617.1 - 0.00025 21.1 8.7 0.00038 20.5 8.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain OPT PF03169.15 KXS20618.1 - 1.8e-115 386.9 39.4 2.6e-115 386.4 39.4 1.2 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF1453 PF07301.11 KXS20618.1 - 0.0051 16.8 0.4 0.0051 16.8 0.4 3.2 3 0 0 3 3 3 1 Protein of unknown function (DUF1453) DUF4535 PF15054.6 KXS20618.1 - 1 9.2 3.2 0.5 10.2 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4535) L27_2 PF09045.10 KXS20619.1 - 0.0077 16.2 0.6 0.14 12.2 0.1 2.2 1 1 1 2 2 2 1 L27_2 Filament PF00038.21 KXS20619.1 - 0.0096 15.5 0.1 0.012 15.3 0.1 1.0 1 0 0 1 1 1 1 Intermediate filament protein Spc7 PF08317.11 KXS20619.1 - 0.015 14.2 0.8 0.016 14.1 0.8 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein DivIC PF04977.15 KXS20619.1 - 0.02 14.7 3.4 0.041 13.7 0.4 2.2 1 1 1 2 2 2 0 Septum formation initiator BLOC1S3 PF15753.5 KXS20619.1 - 0.037 14.2 0.4 0.058 13.5 0.2 1.4 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 Polysacc_deac_2 PF04748.13 KXS20619.1 - 0.044 13.0 0.2 0.05 12.8 0.2 1.1 1 0 0 1 1 1 0 Divergent polysaccharide deacetylase TolA_bind_tri PF16331.5 KXS20619.1 - 0.076 13.1 3.8 19 5.4 0.2 3.3 1 1 2 3 3 3 0 TolA binding protein trimerisation Glyco_hydro_28 PF00295.17 KXS20620.1 - 2.2e-49 168.3 7.9 3.2e-49 167.8 7.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 ubiquitin PF00240.23 KXS20621.1 - 2.2e-22 78.6 0.5 3.3e-22 78.0 0.5 1.3 1 0 0 1 1 1 1 Ubiquitin family ZZ PF00569.17 KXS20621.1 - 7.5e-12 44.9 5.7 1.4e-11 44.1 5.7 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type Rad60-SLD PF11976.8 KXS20621.1 - 2.5e-10 40.0 0.2 3.6e-10 39.5 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KXS20621.1 - 0.024 15.1 0.2 0.066 13.7 0.2 1.7 1 1 0 1 1 1 0 Ubiquitin-like domain Ubiquitin_5 PF18037.1 KXS20621.1 - 0.069 13.5 0.0 0.11 12.9 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-like domain PARP PF00644.20 KXS20623.1 - 1.8e-42 145.2 8.4 4e-36 124.4 0.0 3.2 2 1 1 3 3 3 2 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 KXS20623.1 - 3.9e-29 101.5 0.7 2e-28 99.2 0.7 2.2 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain zf-PARP PF00645.18 KXS20623.1 - 6.4e-28 97.4 2.3 1.9e-14 54.3 0.0 3.3 3 0 0 3 3 3 2 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region WGR PF05406.15 KXS20623.1 - 1.6e-13 50.5 0.7 4.6e-13 49.0 0.2 2.1 2 0 0 2 2 2 1 WGR domain BRCT_2 PF16589.5 KXS20623.1 - 5.2e-07 30.0 0.0 1.5e-06 28.5 0.0 1.8 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 KXS20623.1 - 6.4e-07 29.7 0.0 1.6e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PADR1 PF08063.12 KXS20623.1 - 1.4e-05 24.8 0.0 4.1e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 PADR1 (NUC008) domain SET PF00856.28 KXS20624.1 - 2.1e-07 31.5 0.0 3.8e-05 24.1 0.0 3.3 2 1 0 2 2 2 1 SET domain DUF1972 PF09314.11 KXS20624.1 - 0.053 13.1 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1972) Aldo_ket_red PF00248.21 KXS20625.1 - 8.6e-68 228.7 0.0 1e-67 228.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Fungal_trans PF04082.18 KXS20626.1 - 2.6e-12 46.3 0.2 4.3e-12 45.6 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXS20626.1 - 0.00029 20.9 10.9 0.0007 19.7 10.9 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short_C2 PF13561.6 KXS20627.1 - 3.4e-48 164.3 0.0 5e-48 163.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXS20627.1 - 6.4e-47 159.5 0.0 1.2e-46 158.6 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXS20627.1 - 2.2e-12 47.3 0.0 3.4e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXS20627.1 - 0.014 14.9 0.0 0.3 10.5 0.0 2.0 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 KXS20627.1 - 0.061 12.6 0.0 0.097 12.0 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.18 KXS20627.1 - 0.071 13.0 0.2 0.12 12.3 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 KXS20627.1 - 0.084 12.3 0.1 0.25 10.7 0.0 1.8 2 1 1 3 3 3 0 GDP-mannose 4,6 dehydratase COX7a PF02238.15 KXS20629.1 - 9.7e-07 29.1 0.7 1.2e-06 28.8 0.7 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VII Sds3 PF08598.11 KXS20630.1 - 6.7e-08 32.8 3.8 1.2e-07 31.9 3.8 1.4 1 0 0 1 1 1 1 Sds3-like DUF4407 PF14362.6 KXS20630.1 - 0.81 9.0 7.3 1.4 8.2 7.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CAP PF00188.26 KXS20631.1 - 1.6e-20 74.2 0.1 2.3e-20 73.7 0.1 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Se-cys_synth_N PF12390.8 KXS20632.1 - 0.11 12.8 1.2 6 7.2 0.1 2.3 2 0 0 2 2 2 0 Selenocysteine synthase N terminal Mito_carr PF00153.27 KXS20633.1 - 1.9e-55 184.8 4.9 1.4e-19 69.8 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Acyl-CoA_dh_1 PF00441.24 KXS20634.1 - 1.6e-37 129.0 1.0 2.3e-37 128.5 1.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KXS20634.1 - 2.5e-22 78.9 0.1 5.8e-22 77.7 0.1 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.28 KXS20634.1 - 3.5e-22 78.3 0.0 7.3e-22 77.3 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_2 PF08028.11 KXS20634.1 - 1.9e-07 31.4 0.4 3.1e-07 30.7 0.4 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KXS20634.1 - 7.8e-06 26.5 0.0 7e-05 23.5 0.0 2.3 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain UDPGP PF01704.18 KXS20635.1 - 9.3e-55 185.9 0.0 1.2e-54 185.6 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Dehydratase_hem PF13816.6 KXS20635.1 - 0.19 11.1 0.0 0.31 10.4 0.0 1.2 1 0 0 1 1 1 0 Haem-containing dehydratase Cu2_monoox_C PF03712.15 KXS20636.1 - 9.8e-27 93.4 0.2 2e-26 92.4 0.2 1.5 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain Cu2_monooxygen PF01082.20 KXS20636.1 - 2.1e-23 83.0 0.1 3.4e-23 82.3 0.1 1.3 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain DOMON PF03351.17 KXS20636.1 - 9.4e-19 67.9 0.0 2.1e-18 66.7 0.0 1.7 1 0 0 1 1 1 1 DOMON domain ROQ_II PF18386.1 KXS20636.1 - 0.19 11.6 0.0 0.38 10.6 0.0 1.4 1 0 0 1 1 1 0 Roquin II domain Glyco_transf_28 PF03033.20 KXS20638.1 - 6.1e-23 81.4 0.0 1.5e-22 80.1 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 KXS20638.1 - 9.9e-07 27.9 0.0 1.8e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase VPS13_C PF16909.5 KXS20638.1 - 0.0023 17.7 9.0 0.62 9.8 0.8 3.7 2 1 1 3 3 3 3 Vacuolar-sorting-associated 13 protein C-terminal Peptidase_C97 PF05903.14 KXS20638.1 - 0.06 13.2 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 PPPDE putative peptidase domain ATG_C PF09333.11 KXS20638.1 - 0.15 12.5 0.0 1 9.8 0.0 2.3 2 0 0 2 2 2 0 Autophagy-related protein C terminal domain Aldo_ket_red PF00248.21 KXS20641.1 - 2.5e-48 164.8 0.0 1.4e-46 159.1 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Glycogen_syn PF05693.13 KXS20642.1 - 1e-18 67.3 0.1 1.1e-18 67.2 0.1 1.1 1 0 0 1 1 1 1 Glycogen synthase SWIB PF02201.18 KXS20642.1 - 0.032 14.1 0.0 0.045 13.6 0.0 1.3 1 0 0 1 1 1 0 SWIB/MDM2 domain PPO1_DWL PF12142.8 KXS20642.1 - 0.1 12.4 0.1 0.18 11.6 0.1 1.4 1 0 0 1 1 1 0 Polyphenol oxidase middle domain Aldo_ket_red PF00248.21 KXS20643.1 - 1e-50 172.6 0.0 5.5e-49 167.0 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Glycogen_syn PF05693.13 KXS20645.1 - 8.3e-289 959.6 0.0 9.3e-289 959.4 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.20 KXS20645.1 - 3.8e-06 26.6 0.0 8.3e-05 22.2 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 KXS20645.1 - 4.6e-06 26.5 0.1 1.4e-05 25.0 0.1 1.8 2 0 0 2 2 2 1 Starch synthase catalytic domain Glyco_transf_4 PF13439.6 KXS20645.1 - 1.3e-05 25.3 0.2 3.2e-05 24.0 0.1 1.9 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 KXS20645.1 - 1.8e-05 25.2 0.0 0.0041 17.5 0.0 2.6 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KXS20645.1 - 4.4e-05 24.0 1.6 6e-05 23.5 0.1 2.0 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain DUF1146 PF06612.11 KXS20645.1 - 0.51 10.4 1.9 19 5.4 0.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1146) adh_short PF00106.25 KXS20646.1 - 1.5e-07 31.1 0.1 1.2e-06 28.1 0.1 2.2 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXS20646.1 - 0.0039 16.8 0.0 0.018 14.6 0.0 2.1 2 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Na_Ca_ex PF01699.24 KXS20647.1 - 2e-36 125.3 31.2 4.6e-18 65.6 6.7 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF3169 PF11368.8 KXS20647.1 - 0.16 11.5 1.8 5.2 6.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) Caveolin PF01146.17 KXS20647.1 - 3.7 7.5 5.0 1.9 8.4 0.4 2.7 3 0 0 3 3 3 0 Caveolin PHO4 PF01384.20 KXS20648.1 - 1.1e-118 396.2 18.8 1.5e-118 395.7 18.8 1.2 1 0 0 1 1 1 1 Phosphate transporter family Dr_adhesin PF12393.8 KXS20648.1 - 0.84 10.0 5.1 26 5.3 1.2 3.3 2 0 0 2 2 2 0 Dr family adhesin PEHE PF15275.6 KXS20649.1 - 0.0046 17.6 1.9 0.0046 17.6 1.9 2.6 2 1 0 2 2 2 1 PEHE domain XAP5 PF04921.14 KXS20649.1 - 1.3 8.8 8.4 0.58 9.9 0.4 2.2 2 0 0 2 2 2 0 XAP5, circadian clock regulator DUF724 PF05266.14 KXS20649.1 - 3.6 7.4 13.0 8.7 6.1 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Tom22 PF04281.13 KXS20649.1 - 5.9 6.7 9.8 0.39 10.5 4.6 1.6 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 Ribosomal_L1 PF00687.21 KXS20650.1 - 2.2e-20 73.3 0.0 2.9e-20 72.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Med6 PF04934.14 KXS20651.1 - 4.7e-21 75.0 0.0 6.1e-21 74.6 0.0 1.1 1 0 0 1 1 1 1 MED6 mediator sub complex component KH_1 PF00013.29 KXS20652.1 - 2.8e-110 360.2 51.9 5e-13 48.7 0.2 14.6 14 0 0 14 14 14 13 KH domain KH_2 PF07650.17 KXS20652.1 - 1.2e-17 63.5 15.8 0.17 11.7 0.1 10.6 9 1 1 10 10 10 6 KH domain Secretin_N PF03958.17 KXS20652.1 - 2.6e-05 24.5 5.8 0.15 12.5 0.1 5.3 4 0 0 4 4 4 2 Bacterial type II/III secretion system short domain KH_4 PF13083.6 KXS20652.1 - 0.0017 18.2 19.4 0.21 11.5 0.1 8.7 11 0 0 11 11 11 1 KH domain SOAR PF16533.5 KXS20652.1 - 0.019 15.0 0.1 2.5 8.1 0.0 3.1 2 0 0 2 2 2 0 STIM1 Orai1-activating region KH_5 PF13184.6 KXS20652.1 - 0.025 14.7 12.9 20 5.4 0.0 6.7 6 0 0 6 6 6 0 NusA-like KH domain GST_N_3 PF13417.6 KXS20653.1 - 4.7e-11 42.9 0.0 9.5e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KXS20653.1 - 9.3e-07 29.1 0.0 1.5e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KXS20653.1 - 0.0012 19.1 0.0 0.003 17.9 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain HsdM_N PF12161.8 KXS20653.1 - 0.019 15.6 0.2 0.071 13.7 0.2 1.8 1 1 0 1 1 1 0 HsdM N-terminal domain ROK PF00480.20 KXS20654.1 - 0.073 12.5 0.0 0.09 12.2 0.0 1.2 1 0 0 1 1 1 0 ROK family SPT2 PF08243.11 KXS20655.1 - 2.7e-08 34.3 11.6 2.7e-08 34.3 11.6 2.8 3 0 0 3 3 3 1 SPT2 chromatin protein WD40 PF00400.32 KXS20656.1 - 8.6e-23 80.2 19.9 4.8e-06 27.2 0.0 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat Nucleoporin_N PF08801.11 KXS20656.1 - 2.6e-05 23.2 0.1 0.024 13.4 0.1 2.3 2 0 0 2 2 2 2 Nup133 N terminal like Nup160 PF11715.8 KXS20656.1 - 0.0097 14.6 8.2 1.4 7.5 0.1 4.0 1 1 3 4 4 4 3 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 KXS20656.1 - 0.013 15.8 0.1 6.3 7.2 0.0 2.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Mcl1_mid PF12341.8 KXS20656.1 - 0.023 14.1 0.2 0.048 13.0 0.2 1.6 1 1 0 1 1 1 0 Minichromosome loss protein, Mcl1, middle region WD40_like PF17005.5 KXS20656.1 - 0.25 10.6 0.0 1.6 8.0 0.0 1.9 1 1 1 2 2 2 0 WD40-like domain GATase_2 PF00310.21 KXS20657.1 - 2e-185 616.5 0.0 2.7e-185 616.1 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 KXS20657.1 - 5.7e-150 499.5 0.0 1.2e-149 498.4 0.0 1.6 2 0 0 2 2 1 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 KXS20657.1 - 6.4e-109 363.8 0.0 7.2e-108 360.3 0.0 2.3 3 0 0 3 3 2 1 Glutamate synthase central domain GXGXG PF01493.19 KXS20657.1 - 1e-87 292.7 3.1 1.7e-87 292.0 3.1 1.3 1 0 0 1 1 1 1 GXGXG motif Pyr_redox_2 PF07992.14 KXS20657.1 - 1.8e-22 79.9 0.6 3.5e-15 56.0 0.2 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 KXS20657.1 - 3.5e-22 78.3 0.0 7.3e-22 77.3 0.0 1.5 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster NAD_binding_8 PF13450.6 KXS20657.1 - 6.3e-09 35.9 0.0 2.1e-08 34.3 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXS20657.1 - 4.5e-06 26.5 1.2 0.0029 17.2 0.2 2.7 3 0 0 3 3 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 KXS20657.1 - 6.1e-06 26.7 0.1 3.3e-05 24.3 0.1 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KXS20657.1 - 1.3e-05 24.7 0.0 2.1e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 KXS20657.1 - 3.2e-05 23.5 0.1 6.3e-05 22.5 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KXS20657.1 - 3.8e-05 23.1 0.3 0.00061 19.1 0.0 2.6 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXS20657.1 - 5.5e-05 22.0 0.1 5.5e-05 22.0 0.1 1.6 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.19 KXS20657.1 - 0.00072 18.9 0.0 0.0013 18.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 KXS20657.1 - 0.0015 17.7 0.2 0.0015 17.7 0.2 1.9 2 0 0 2 2 1 1 FAD binding domain Thi4 PF01946.17 KXS20657.1 - 0.01 15.1 0.1 0.048 12.9 0.0 2.1 2 0 0 2 2 2 0 Thi4 family NAD_binding_7 PF13241.6 KXS20657.1 - 0.027 14.9 0.3 0.29 11.6 0.1 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding AlaDh_PNT_C PF01262.21 KXS20657.1 - 0.045 13.0 0.1 0.11 11.8 0.1 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 KXS20657.1 - 0.057 12.8 0.0 0.16 11.3 0.0 1.7 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GIDA PF01134.22 KXS20657.1 - 0.081 12.0 0.1 0.17 11.0 0.1 1.6 1 0 0 1 1 1 0 Glucose inhibited division protein A ApbA PF02558.16 KXS20657.1 - 0.097 12.3 0.1 0.21 11.2 0.1 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 KXS20657.1 - 0.12 12.3 0.1 0.29 11.0 0.1 1.7 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.6 KXS20657.1 - 0.13 12.2 0.0 0.37 10.8 0.0 1.8 1 0 0 1 1 1 0 FAD-NAD(P)-binding GATase_6 PF13522.6 KXS20657.1 - 0.16 12.2 0.0 0.43 10.8 0.0 1.7 1 0 0 1 1 1 0 Glutamine amidotransferase domain NAD_Gly3P_dh_N PF01210.23 KXS20657.1 - 0.16 11.9 0.3 0.49 10.4 0.1 1.9 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus SNO PF01174.19 KXS20658.1 - 8.1e-44 149.7 0.0 6.1e-29 101.2 0.0 2.0 2 0 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.14 KXS20658.1 - 1.5e-07 31.2 0.0 3.6e-07 30.0 0.0 1.5 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.28 KXS20658.1 - 0.0019 18.0 0.0 1.3 8.7 0.0 2.1 2 0 0 2 2 2 2 Glutamine amidotransferase class-I DJ-1_PfpI PF01965.24 KXS20658.1 - 0.0019 18.0 0.0 0.0029 17.5 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family Peptidase_S51 PF03575.17 KXS20658.1 - 0.012 15.2 0.0 0.017 14.7 0.0 1.1 1 0 0 1 1 1 0 Peptidase family S51 DUF3180 PF11377.8 KXS20660.1 - 0.077 13.1 0.1 0.077 13.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3180) adh_short PF00106.25 KXS20661.1 - 1.5e-13 50.6 0.0 3.1e-13 49.6 0.1 1.4 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXS20661.1 - 7.7e-08 32.2 0.0 1.2e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXS20661.1 - 1.6e-05 24.9 0.2 2.5e-05 24.3 0.2 1.3 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 KXS20661.1 - 0.00076 18.8 0.1 0.0013 18.1 0.1 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Shikimate_DH PF01488.20 KXS20661.1 - 0.028 14.5 0.1 0.057 13.5 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 KXS20661.1 - 0.041 13.5 0.2 0.54 9.9 0.1 2.4 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA Carb_anhydrase PF00194.21 KXS20663.1 - 1.1e-35 123.4 0.0 2.2e-35 122.4 0.0 1.4 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Sulfate_transp PF00916.20 KXS20664.1 - 5.8e-50 170.1 25.1 7.5e-50 169.8 25.1 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KXS20664.1 - 7.5e-08 32.0 0.0 1.5e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 STAS domain CPP1-like PF11833.8 KXS20664.1 - 0.041 13.5 0.1 0.041 13.5 0.1 2.6 3 0 0 3 3 3 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Condensin2nSMC PF12422.8 KXS20665.1 - 6.3e-47 159.5 0.0 5.7e-46 156.4 0.0 2.6 2 0 0 2 2 2 1 Condensin II non structural maintenance of chromosomes subunit HEAT PF02985.22 KXS20665.1 - 7.9e-07 28.8 0.9 0.22 11.9 0.1 5.7 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.6 KXS20665.1 - 2.2e-06 28.0 2.7 0.064 13.7 0.0 5.1 5 0 0 5 5 5 2 HEAT repeats Cnd1 PF12717.7 KXS20665.1 - 0.014 15.4 0.3 0.86 9.6 0.1 3.2 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 PriCT_1 PF08708.11 KXS20665.1 - 0.017 14.9 0.1 0.3 10.9 0.0 2.5 2 0 0 2 2 2 0 Primase C terminal 1 (PriCT-1) CLASP_N PF12348.8 KXS20665.1 - 0.033 13.8 0.2 13 5.3 0.0 3.1 2 1 1 3 3 3 0 CLASP N terminal GTP_EFTU PF00009.27 KXS20666.1 - 1.1e-29 103.4 0.0 1.9e-29 102.6 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 KXS20666.1 - 4.9e-10 39.7 0.1 1.1e-09 38.6 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KXS20666.1 - 1.2e-06 28.6 0.0 2e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 KXS20666.1 - 6.2e-05 22.5 0.0 0.00019 20.9 0.0 1.7 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit zf-SAP30 PF13866.6 KXS20666.1 - 0.033 14.3 0.3 0.11 12.6 0.1 2.0 2 0 0 2 2 2 0 SAP30 zinc-finger RIBIOP_C PF04950.12 KXS20666.1 - 0.048 13.1 1.3 0.06 12.8 0.0 1.8 2 0 0 2 2 2 0 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal G-alpha PF00503.20 KXS20666.1 - 0.13 11.4 0.0 0.51 9.5 0.0 1.8 2 0 0 2 2 2 0 G-protein alpha subunit Prenylcys_lyase PF07156.14 KXS20667.1 - 9.4e-18 64.4 0.0 2.3e-17 63.2 0.0 1.5 1 1 0 1 1 1 1 Prenylcysteine lyase Pyr_redox_2 PF07992.14 KXS20667.1 - 1.1e-09 38.0 0.0 0.00081 18.7 0.0 2.9 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXS20667.1 - 1.6e-05 24.9 0.0 0.083 12.9 0.0 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding Thi4 PF01946.17 KXS20667.1 - 3.6e-05 23.1 0.2 6e-05 22.4 0.2 1.2 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 KXS20667.1 - 4.4e-05 23.6 0.2 0.00032 20.9 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KXS20667.1 - 0.00043 19.7 0.0 0.0008 18.8 0.0 1.5 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase DAO PF01266.24 KXS20667.1 - 0.0013 18.3 0.3 0.018 14.6 0.3 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KXS20667.1 - 0.061 12.6 0.0 9.5 5.4 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXS20667.1 - 0.084 11.6 0.1 9.6 4.8 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein RPAP1_C PF08620.10 KXS20668.1 - 4e-17 62.1 0.0 9e-17 60.9 0.0 1.6 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.10 KXS20668.1 - 2.6e-12 46.3 3.7 5e-12 45.4 3.7 1.4 1 0 0 1 1 1 1 RPAP1-like, N-terminal Pkr1 PF08636.10 KXS20669.1 - 7.4e-16 58.0 7.1 1e-15 57.6 7.1 1.1 1 0 0 1 1 1 1 ER protein Pkr1 ATP-sulfurylase PF01747.17 KXS20670.1 - 2.9e-87 291.6 0.0 4.3e-87 291.1 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.20 KXS20670.1 - 1.7e-51 174.2 0.0 2.5e-51 173.7 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.6 KXS20670.1 - 2.9e-49 166.8 0.0 4.6e-49 166.1 0.0 1.3 1 0 0 1 1 1 1 PUA-like domain RRM_1 PF00076.22 KXS20671.1 - 2.6e-43 145.7 0.0 7.2e-21 73.8 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KXS20671.1 - 5.1e-06 26.2 0.0 0.025 14.4 0.0 2.4 2 0 0 2 2 2 2 Occluded RNA-recognition motif RRM_7 PF16367.5 KXS20671.1 - 0.0014 18.7 0.0 2.4 8.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif Limkain-b1 PF11608.8 KXS20671.1 - 0.0029 17.7 0.0 3.6 7.7 0.0 2.4 2 0 0 2 2 2 2 Limkain b1 DUF4140 PF13600.6 KXS20671.1 - 0.013 15.9 0.0 0.052 14.0 0.0 1.9 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) RRM_5 PF13893.6 KXS20671.1 - 0.014 14.9 0.0 3.3 7.3 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 KXS20671.1 - 0.022 15.0 0.0 3.2 7.9 0.0 2.3 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter DbpA PF03880.15 KXS20671.1 - 0.029 14.4 0.0 8.7 6.4 0.0 2.3 2 0 0 2 2 2 0 DbpA RNA binding domain YqfQ PF14181.6 KXS20671.1 - 0.79 9.9 3.3 0.71 10.0 0.1 2.2 2 0 0 2 2 2 0 YqfQ-like protein FOXP-CC PF16159.5 KXS20672.1 - 0.00018 22.0 2.1 0.00018 22.0 2.1 2.1 2 1 1 3 3 3 2 FOXP coiled-coil domain RFX_DNA_binding PF02257.15 KXS20673.1 - 6.8e-05 23.4 0.0 0.00012 22.6 0.0 1.4 1 0 0 1 1 1 1 RFX DNA-binding domain BAF250_C PF12031.8 KXS20673.1 - 0.0043 16.4 0.2 1 8.6 0.0 2.3 2 0 0 2 2 2 2 SWI/SNF-like complex subunit BAF250/Osa RRM_1 PF00076.22 KXS20674.1 - 6.1e-23 80.4 0.0 5.6e-16 58.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DnaJ PF00226.31 KXS20676.1 - 6.9e-18 64.5 0.1 1.5e-17 63.4 0.1 1.6 1 0 0 1 1 1 1 DnaJ domain Sec63 PF02889.16 KXS20676.1 - 1.3e-11 44.1 0.0 2e-06 27.1 0.0 2.3 2 1 0 2 2 2 2 Sec63 Brl domain dCMP_cyt_deam_1 PF00383.23 KXS20678.1 - 3.7e-26 90.9 1.1 5.7e-26 90.3 1.1 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KXS20678.1 - 1e-13 51.2 0.2 1.6e-13 50.6 0.2 1.3 1 0 0 1 1 1 1 MafB19-like deaminase AAA_18 PF13238.6 KXS20678.1 - 2.1e-05 25.0 0.0 5e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KXS20678.1 - 0.00092 19.4 0.0 0.0022 18.1 0.0 1.7 2 0 0 2 2 2 1 AAA domain SNAD4 PF18750.1 KXS20678.1 - 0.017 15.2 0.2 0.033 14.3 0.2 1.5 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC_N PF08210.11 KXS20678.1 - 0.09 12.7 0.5 0.15 11.9 0.5 1.5 1 1 0 1 1 1 0 APOBEC-like N-terminal domain Cytidylate_kin PF02224.18 KXS20678.1 - 0.14 11.8 0.0 0.31 10.7 0.0 1.5 1 0 0 1 1 1 0 Cytidylate kinase NAD1 PF18778.1 KXS20678.1 - 0.15 12.1 0.2 0.3 11.2 0.2 1.4 1 0 0 1 1 1 0 Novel AID APOBEC clade 1 Nbs1_C PF08599.10 KXS20679.1 - 0.019 15.1 0.3 0.14 12.3 0.3 2.6 1 0 0 1 1 1 0 DNA damage repair protein Nbs1 WXG100 PF06013.12 KXS20679.1 - 2.1 8.6 22.9 2.8 8.2 0.1 7.3 5 3 1 7 7 7 0 Proteins of 100 residues with WXG Carn_acyltransf PF00755.20 KXS20680.1 - 7.7e-170 566.4 0.0 8.7e-170 566.2 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Peptidase_S41 PF03572.18 KXS20685.1 - 9.1e-19 67.6 0.0 1.3e-18 67.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family S41 Peptidase_S41_N PF11918.8 KXS20685.1 - 1.9e-09 37.8 0.0 3.4e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of Peptidase_S41 in eukaryotic IRBP SGL PF08450.12 KXS20686.1 - 9e-34 117.1 1.9 2.8e-33 115.5 0.7 1.9 1 1 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 KXS20686.1 - 7.8e-05 22.5 0.4 3.6 7.8 0.0 4.6 4 0 0 4 4 4 1 NHL repeat Str_synth PF03088.16 KXS20686.1 - 0.062 13.4 0.0 1.2 9.3 0.0 2.5 1 1 1 2 2 2 0 Strictosidine synthase Phytase-like PF13449.6 KXS20686.1 - 0.064 13.2 0.0 0.24 11.3 0.0 2.1 1 1 0 1 1 1 0 Esterase-like activity of phytase Arylesterase PF01731.20 KXS20686.1 - 0.069 13.4 0.1 8.3 6.7 0.0 3.1 3 0 0 3 3 3 0 Arylesterase Lactonase PF10282.9 KXS20686.1 - 0.092 12.0 0.0 4.6 6.4 0.0 2.4 1 1 0 2 2 2 0 Lactonase, 7-bladed beta-propeller FLYWCH PF04500.16 KXS20686.1 - 0.23 11.6 0.0 0.47 10.6 0.0 1.4 1 0 0 1 1 1 0 FLYWCH zinc finger domain FAP PF07174.11 KXS20686.1 - 5.1 6.5 18.1 7.7 5.9 18.1 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) DUF1223 PF06764.11 KXS20687.1 - 7.3e-43 147.0 0.0 1.4e-42 146.0 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1223) eIF-5_eIF-2B PF01873.17 KXS20688.1 - 2.4e-40 137.0 0.0 4.7e-40 136.1 0.0 1.5 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.18 KXS20688.1 - 6.3e-23 80.7 0.7 6.3e-23 80.7 0.7 1.9 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon DNA_RNApol_7kD PF03604.13 KXS20688.1 - 0.058 13.1 2.6 0.13 11.9 2.6 1.5 1 0 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit Ribosomal_L37e PF01907.19 KXS20688.1 - 0.081 13.1 1.7 0.44 10.7 0.5 2.2 2 0 0 2 2 2 0 Ribosomal protein L37e zf-NADH-PPase PF09297.11 KXS20688.1 - 0.49 10.1 1.7 2.5 7.9 1.7 2.0 1 1 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain Fungal_trans PF04082.18 KXS20689.1 - 6.7e-25 87.6 0.1 1.2e-24 86.8 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXS20689.1 - 1.1e-09 38.3 11.6 1.8e-09 37.6 11.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Adenylsucc_synt PF00709.21 KXS20690.1 - 5.3e-174 579.1 0.0 6e-174 578.9 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase cNMP_binding PF00027.29 KXS20691.1 - 1.9e-20 72.7 0.1 6.1e-19 67.9 0.1 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain LRR_6 PF13516.6 KXS20692.1 - 2.1e-10 39.8 3.6 0.0077 16.2 0.0 6.6 7 0 0 7 7 7 3 Leucine Rich repeat LRR_4 PF12799.7 KXS20692.1 - 2e-07 31.2 1.0 0.21 12.1 0.2 4.8 3 1 2 5 5 5 2 Leucine Rich repeats (2 copies) F-box PF00646.33 KXS20692.1 - 0.00013 21.7 2.0 0.00017 21.4 0.3 2.1 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KXS20692.1 - 0.0013 18.6 0.3 0.0035 17.2 0.3 1.8 1 0 0 1 1 1 1 F-box-like LRR_1 PF00560.33 KXS20692.1 - 0.017 15.6 12.6 3.2 8.6 0.1 7.1 8 1 1 9 9 9 0 Leucine Rich Repeat LRR_8 PF13855.6 KXS20692.1 - 0.02 14.7 2.7 0.53 10.1 1.1 3.7 3 1 1 4 4 4 0 Leucine rich repeat F-box_4 PF15966.5 KXS20692.1 - 0.053 13.4 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 F-box zf-RING_2 PF13639.6 KXS20693.1 - 9.4e-10 38.7 5.5 1.2e-09 38.4 2.6 2.1 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 KXS20693.1 - 4.1e-09 36.6 5.4 1.3e-08 35.0 5.4 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KXS20693.1 - 3.7e-07 29.9 0.5 7.5e-07 28.9 0.5 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXS20693.1 - 1.1e-06 28.3 3.1 1.1e-06 28.3 3.1 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXS20693.1 - 2.5e-06 27.4 0.3 5.7e-06 26.3 0.3 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KXS20693.1 - 1.3e-05 25.0 3.2 0.00012 21.8 1.4 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXS20693.1 - 2.2e-05 24.3 0.4 4.4e-05 23.3 0.4 1.5 1 1 0 1 1 1 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 KXS20693.1 - 0.0003 20.4 0.4 0.00074 19.1 0.4 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 KXS20693.1 - 0.00042 20.1 3.6 0.001 18.9 3.6 1.7 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KXS20693.1 - 0.0017 18.5 0.8 0.0047 17.0 0.8 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 KXS20693.1 - 0.0021 17.8 0.1 0.0021 17.8 0.1 2.0 2 0 0 2 2 2 1 RING-like zinc finger zf-ANAPC11 PF12861.7 KXS20693.1 - 0.0033 17.4 0.8 0.0033 17.4 0.8 1.7 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger TRC8_N PF13705.6 KXS20693.1 - 0.0086 15.0 1.6 0.013 14.4 1.6 1.2 1 0 0 1 1 1 1 TRC8 N-terminal domain Rtf2 PF04641.12 KXS20693.1 - 0.16 11.3 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger FANCL_C PF11793.8 KXS20693.1 - 0.16 12.2 0.3 0.38 11.0 0.3 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.6 KXS20693.1 - 1.4 8.8 4.2 1.4 8.8 1.6 2.0 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Choline_transpo PF04515.12 KXS20695.1 - 2.8e-93 312.7 26.0 2.8e-93 312.7 26.0 2.8 3 0 0 3 3 3 1 Plasma-membrane choline transporter dUTPase PF00692.19 KXS20696.1 - 3.2e-08 33.3 0.0 5e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 dUTPase DCD PF06559.11 KXS20696.1 - 0.0068 15.2 0.0 0.021 13.6 0.0 1.8 1 1 0 1 1 1 1 2'-deoxycytidine 5'-triphosphate deaminase (DCD) RNA_pol_L PF01193.24 KXS20696.1 - 0.18 11.3 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb3/Rpb11 dimerisation domain Pinin_SDK_memA PF04696.13 KXS20697.1 - 2.5e-27 95.5 19.7 4e-27 94.8 19.7 1.3 1 0 0 1 1 1 1 pinin/SDK/memA/ protein conserved region AAA_assoc_C PF09821.9 KXS20697.1 - 0.41 11.2 6.3 0.074 13.6 2.3 1.8 1 1 1 2 2 2 0 C-terminal AAA-associated domain Cupin_8 PF13621.6 KXS20697.1 - 0.61 9.7 7.1 1.3 8.7 7.1 1.6 1 1 0 1 1 1 0 Cupin-like domain LMBR1 PF04791.16 KXS20697.1 - 3.5 6.4 5.1 4.6 6.0 5.1 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein SET PF00856.28 KXS20698.1 - 2.2e-11 44.5 0.0 3.3e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 SET domain tRNA_U5-meth_tr PF05958.11 KXS20699.1 - 6.3e-12 45.2 0.1 2.5e-11 43.2 0.1 1.9 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_25 PF13649.6 KXS20699.1 - 3e-09 37.5 0.0 7.2e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXS20699.1 - 5.7e-09 35.9 0.0 1.1e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.10 KXS20699.1 - 3.1e-07 30.1 0.0 5.1e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Cons_hypoth95 PF03602.15 KXS20699.1 - 3.4e-07 30.1 0.1 3.6e-05 23.5 0.0 2.7 2 1 1 3 3 3 1 Conserved hypothetical protein 95 MTS PF05175.14 KXS20699.1 - 1.7e-06 27.7 0.0 3.1e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 KXS20699.1 - 5.8e-06 26.9 0.0 1.4e-05 25.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KXS20699.1 - 8.3e-06 25.4 0.1 1.6e-05 24.4 0.1 1.5 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.13 KXS20699.1 - 0.00031 20.2 0.2 0.00057 19.4 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 KXS20699.1 - 0.00051 19.4 0.1 0.00094 18.6 0.1 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family N6_N4_Mtase PF01555.18 KXS20699.1 - 0.0011 18.7 0.0 0.0026 17.5 0.0 1.6 1 0 0 1 1 1 1 DNA methylase NodS PF05401.11 KXS20699.1 - 0.0083 15.8 1.7 0.011 15.4 0.3 1.8 2 0 0 2 2 2 1 Nodulation protein S (NodS) PCMT PF01135.19 KXS20699.1 - 0.0094 15.7 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Met_10 PF02475.16 KXS20699.1 - 0.012 15.4 0.1 0.031 14.0 0.1 1.7 2 0 0 2 2 2 0 Met-10+ like-protein Methyltransf_12 PF08242.12 KXS20699.1 - 0.12 13.1 0.0 0.29 11.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Anoctamin PF04547.12 KXS20700.1 - 8.8e-76 255.5 0.1 1.1e-75 255.2 0.1 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel ABC2_membrane_2 PF12679.7 KXS20700.1 - 0.67 9.2 5.6 7.8 5.7 0.0 2.5 2 0 0 2 2 2 0 ABC-2 family transporter protein Zn_clus PF00172.18 KXS20701.1 - 7.2e-10 38.8 14.4 1.1e-09 38.2 14.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2039 PF10217.9 KXS20701.1 - 0.4 11.1 10.3 0.46 10.8 10.3 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) Fungal_trans PF04082.18 KXS20702.1 - 6.7e-40 136.8 0.4 9.7e-40 136.3 0.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain PsbX PF06596.11 KXS20703.1 - 3.4 7.7 9.4 5.8 7.0 9.4 1.3 1 0 0 1 1 1 0 Photosystem II reaction centre X protein (PsbX) Citrate_synt PF00285.21 KXS20704.1 - 1.5e-95 320.3 0.0 1.8e-95 320.1 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain zf_CCCH_4 PF18345.1 KXS20705.1 - 8.2e-12 44.8 43.8 5e-06 26.4 2.0 6.0 5 1 0 5 5 5 3 Zinc finger domain Torus PF16131.5 KXS20705.1 - 1.6e-10 41.6 14.5 1.6e-07 32.0 2.5 3.2 1 1 2 3 3 3 2 Torus domain zf-CCCH PF00642.24 KXS20705.1 - 9e-10 38.2 33.2 0.00011 22.0 0.9 4.8 4 1 0 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KXS20705.1 - 0.00018 21.2 39.5 0.0032 17.2 0.4 5.5 4 2 0 4 4 4 2 CCCH-type zinc finger zf-CCCH_3 PF15663.5 KXS20705.1 - 0.0011 19.1 17.9 0.3 11.3 0.3 3.2 1 1 2 3 3 3 2 Zinc-finger containing family zf-CCCH_2 PF14608.6 KXS20705.1 - 0.0048 17.3 1.6 0.0048 17.3 1.6 5.2 4 2 0 4 4 4 3 RNA-binding, Nab2-type zinc finger Methyltransf_32 PF13679.6 KXS20706.1 - 0.023 14.7 0.0 0.033 14.2 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 KXS20706.1 - 0.076 12.8 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Microcin PF03526.13 KXS20706.1 - 0.16 11.8 0.1 0.32 10.8 0.1 1.4 1 0 0 1 1 1 0 Colicin E1 (microcin) immunity protein HATPase_c PF02518.26 KXS20707.1 - 4e-29 101.4 0.0 8.9e-29 100.3 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KXS20707.1 - 4.3e-19 68.7 0.0 1.2e-18 67.3 0.0 1.8 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 KXS20707.1 - 9.6e-18 64.0 0.3 3.5e-17 62.2 0.1 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain ADH_N PF08240.12 KXS20710.1 - 8.8e-25 86.7 0.4 1.6e-24 85.9 0.4 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXS20710.1 - 1.1e-05 25.5 0.0 0.0014 18.6 0.0 2.4 1 1 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KXS20710.1 - 0.0019 17.6 0.0 0.0038 16.6 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Myb_DNA-binding PF00249.31 KXS20713.1 - 0.14 12.4 3.3 0.48 10.7 3.3 1.9 1 1 0 1 1 1 0 Myb-like DNA-binding domain Acyl-CoA_dh_1 PF00441.24 KXS20714.1 - 2.1e-21 76.7 4.9 2.9e-21 76.2 4.9 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KXS20714.1 - 4.5e-10 39.6 0.0 1.4e-09 38.0 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KXS20714.1 - 2.8e-06 27.6 4.7 5e-06 26.8 4.7 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Vps54 PF07928.12 KXS20714.1 - 0.2 12.1 0.0 0.33 11.4 0.0 1.3 1 0 0 1 1 1 0 Vps54-like protein MutS_V PF00488.21 KXS20715.1 - 2.3e-78 262.5 0.2 3.8e-78 261.9 0.2 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KXS20715.1 - 3.5e-31 108.9 0.8 8.9e-31 107.6 0.1 2.0 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.18 KXS20715.1 - 4.9e-19 68.5 0.6 1e-18 67.4 0.6 1.6 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.17 KXS20715.1 - 1.1e-17 64.6 0.4 3.6e-17 62.9 0.1 2.1 2 0 0 2 2 2 1 MutS domain II MutS_I PF01624.20 KXS20715.1 - 7.1e-12 45.6 0.0 1.8e-11 44.2 0.0 1.7 1 0 0 1 1 1 1 MutS domain I AAA_27 PF13514.6 KXS20715.1 - 0.00095 18.8 0.7 0.0063 16.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 KXS20715.1 - 0.17 12.4 1.1 1.2 9.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain Enkurin PF13864.6 KXS20715.1 - 1.3 9.5 3.7 12 6.4 0.0 3.3 3 1 0 3 3 3 0 Calmodulin-binding adh_short PF00106.25 KXS20716.1 - 1.5e-29 102.9 0.0 8.8e-27 93.8 0.0 2.2 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXS20716.1 - 1.2e-16 61.0 0.0 6.8e-11 42.2 0.0 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXS20716.1 - 2.8e-05 24.1 0.0 4.6e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXS20716.1 - 0.0041 16.6 0.1 0.021 14.3 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KXS20716.1 - 0.0065 15.6 0.1 0.01 15.0 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KXS20716.1 - 0.081 12.3 0.0 2.4 7.5 0.0 2.1 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase THF_DHG_CYH_C PF02882.19 KXS20716.1 - 0.12 11.7 0.2 11 5.3 0.0 2.5 3 0 0 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain AAA_22 PF13401.6 KXS20718.1 - 3.1e-06 27.5 0.0 6.9e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KXS20718.1 - 1.6e-05 25.3 0.0 3.1e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KXS20718.1 - 2.7e-05 24.6 0.3 0.00014 22.3 0.1 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_lid_10 PF17872.1 KXS20718.1 - 0.00028 21.0 0.1 0.00056 20.0 0.1 1.4 1 0 0 1 1 1 1 AAA lid domain AAA_19 PF13245.6 KXS20718.1 - 0.041 14.2 0.1 0.088 13.1 0.1 1.5 1 0 0 1 1 1 0 AAA domain AKNA PF12443.8 KXS20718.1 - 0.097 13.3 0.2 1.1 9.9 0.0 2.7 2 0 0 2 2 2 0 AT-hook-containing transcription factor NACHT PF05729.12 KXS20718.1 - 0.11 12.5 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 NACHT domain TniB PF05621.11 KXS20718.1 - 0.24 10.8 0.0 0.41 10.0 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein ANAPC4_WD40 PF12894.7 KXS20720.1 - 1e-07 32.1 0.0 0.016 15.5 0.0 4.1 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KXS20720.1 - 9.2e-07 29.5 1.5 2.3 9.3 0.0 5.4 5 0 0 5 5 5 2 WD domain, G-beta repeat PQQ_3 PF13570.6 KXS20720.1 - 0.012 16.1 5.3 4.6 7.9 0.9 4.1 3 0 0 3 3 3 0 PQQ-like domain Cytochrom_D1 PF02239.16 KXS20720.1 - 0.038 12.5 0.0 0.067 11.7 0.0 1.3 1 0 0 1 1 1 0 Cytochrome D1 heme domain TFIIIC_delta PF12657.7 KXS20720.1 - 0.11 12.5 0.1 0.47 10.4 0.0 2.1 2 1 0 2 2 2 0 Transcription factor IIIC subunit delta N-term DUF3712 PF12505.8 KXS20721.1 - 2.2e-07 31.2 1.9 2.2e-07 31.2 1.9 2.7 2 2 0 2 2 2 1 Protein of unknown function (DUF3712) LEA_2 PF03168.13 KXS20721.1 - 5.4 7.6 8.8 12 6.5 0.2 3.4 3 1 1 4 4 4 0 Late embryogenesis abundant protein DUF3712 PF12505.8 KXS20722.1 - 5.1e-45 152.8 23.6 5.7e-22 78.3 0.1 6.1 6 0 0 6 6 6 4 Protein of unknown function (DUF3712) LEA_2 PF03168.13 KXS20722.1 - 8.4e-14 51.9 10.1 0.0007 20.1 0.0 8.1 7 0 0 7 7 7 3 Late embryogenesis abundant protein Cupredoxin_1 PF13473.6 KXS20722.1 - 0.024 14.7 0.4 6.7 6.9 0.0 3.3 3 0 0 3 3 3 0 Cupredoxin-like domain Herpes_U55 PF06501.11 KXS20722.1 - 0.21 10.3 0.2 23 3.6 0.0 2.8 3 0 0 3 3 3 0 Human herpesvirus U55 protein Reo_sigmaC PF04582.12 KXS20722.1 - 0.22 11.8 2.5 17 5.7 0.1 4.2 4 1 1 5 5 5 0 Reovirus sigma C capsid protein C-terminal domain GHMP_kinases_N PF00288.26 KXS20723.1 - 8.1e-13 48.4 4.0 1.4e-11 44.4 4.0 2.4 1 1 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KXS20723.1 - 2.7e-07 30.8 0.0 7e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal CTP_transf_like PF01467.26 KXS20725.1 - 1.9e-05 24.9 0.0 4.4e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Cytidylyltransferase-like RRM_1 PF00076.22 KXS20726.1 - 1.6e-17 63.0 0.0 2.5e-17 62.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RL PF17797.1 KXS20726.1 - 0.13 12.2 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 RL domain Nup35_RRM_2 PF14605.6 KXS20726.1 - 0.15 12.1 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Ribonuc_L-PSP PF01042.21 KXS20727.1 - 1.3e-27 96.2 0.0 1.5e-27 96.0 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP tRNA-synt_2 PF00152.20 KXS20729.1 - 2.1e-90 303.0 0.1 5e-90 301.8 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KXS20729.1 - 1.3e-11 44.3 0.0 2.8e-11 43.2 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Gpi16 PF04113.14 KXS20730.1 - 4.1e-144 481.1 0.0 6.4e-143 477.2 0.0 1.9 1 1 0 1 1 1 1 Gpi16 subunit, GPI transamidase component Apolipoprotein PF01442.18 KXS20731.1 - 0.00014 21.8 14.6 0.00021 21.3 14.6 1.3 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain FAM184 PF15665.5 KXS20731.1 - 0.0008 19.2 18.8 0.065 13.0 8.1 2.2 1 1 1 2 2 2 2 Family with sequence similarity 184, A and B TPR_MLP1_2 PF07926.12 KXS20731.1 - 0.0055 16.8 7.8 0.0055 16.8 7.8 2.2 2 0 0 2 2 2 1 TPR/MLP1/MLP2-like protein DLP_helical PF18709.1 KXS20731.1 - 0.0056 15.9 10.1 0.01 15.1 10.1 1.4 1 1 0 1 1 1 1 Dynamin-like helical domain Hormone_1 PF00103.20 KXS20731.1 - 0.016 15.0 3.2 0.039 13.7 0.3 2.3 1 1 1 2 2 2 0 Somatotropin hormone family DUF3482 PF11981.8 KXS20731.1 - 0.059 12.8 9.3 0.035 13.5 6.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3482) T7SS_ESX_EspC PF10824.8 KXS20731.1 - 0.098 13.1 3.3 0.22 12.0 0.3 2.8 2 1 1 3 3 3 0 Excreted virulence factor EspC, type VII ESX diderm DnaG_DnaB_bind PF08278.11 KXS20731.1 - 0.11 13.1 6.8 0.15 12.7 6.1 1.6 1 1 0 1 1 1 0 DNA primase DnaG DnaB-binding Baculo_PEP_C PF04513.12 KXS20731.1 - 0.11 12.5 4.3 1.5 8.8 3.9 2.5 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1043 PF06295.12 KXS20731.1 - 0.14 12.2 7.7 7.4 6.6 4.8 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1043) CK2S PF15011.6 KXS20731.1 - 0.14 12.0 8.1 0.12 12.2 3.9 2.2 1 1 1 2 2 2 0 Casein Kinase 2 substrate RB_A PF01858.17 KXS20731.1 - 0.18 11.6 4.3 0.59 9.9 4.3 1.9 1 1 0 1 1 1 0 Retinoblastoma-associated protein A domain Muted PF14942.6 KXS20731.1 - 0.2 12.0 14.9 0.082 13.3 6.8 2.4 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein Gasdermin_C PF17708.1 KXS20731.1 - 0.25 11.4 4.4 0.17 12.0 1.1 2.0 2 0 0 2 2 2 0 Gasdermin PUB domain CorA PF01544.18 KXS20731.1 - 0.27 10.5 7.7 0.39 10.0 7.7 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein ApoLp-III PF07464.11 KXS20731.1 - 0.29 11.2 8.9 1.3 9.2 8.9 2.0 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) DUF948 PF06103.11 KXS20731.1 - 0.71 10.2 7.9 3.9 7.8 1.4 2.7 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Fib_alpha PF08702.10 KXS20731.1 - 0.99 9.6 10.7 1.8 8.7 9.2 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family FUSC PF04632.12 KXS20731.1 - 1.1 7.7 2.9 1.4 7.4 2.9 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF4407 PF14362.6 KXS20731.1 - 2.5 7.4 10.8 3.3 7.0 10.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Prominin PF05478.11 KXS20731.1 - 2.7 5.8 7.8 1.1 7.2 4.0 1.5 1 1 0 1 1 1 0 Prominin Exonuc_VII_L PF02601.15 KXS20731.1 - 3.3 7.2 12.6 4 6.9 11.7 1.5 1 1 0 1 1 1 0 Exonuclease VII, large subunit Ras PF00071.22 KXS20732.1 - 4.3e-38 130.5 0.0 5.3e-38 130.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXS20732.1 - 8.6e-33 113.1 0.0 1.3e-32 112.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXS20732.1 - 6.5e-09 35.5 0.0 9.3e-09 35.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KXS20732.1 - 9.2e-07 28.4 0.0 1.2e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KXS20732.1 - 1.6e-05 24.9 0.0 3.5e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KXS20732.1 - 3.4e-05 23.5 0.0 0.00042 19.9 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KXS20732.1 - 0.00032 20.6 0.0 0.71 9.8 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 KXS20732.1 - 0.0018 18.7 0.0 0.0065 16.9 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain TniB PF05621.11 KXS20732.1 - 0.025 14.0 0.0 0.064 12.7 0.0 1.7 1 0 0 1 1 1 0 Bacterial TniB protein AAA_22 PF13401.6 KXS20732.1 - 0.062 13.6 0.0 0.75 10.1 0.0 2.3 1 1 2 3 3 3 0 AAA domain ABC_tran PF00005.27 KXS20732.1 - 0.066 13.7 0.0 6.7 7.2 0.0 2.3 1 1 0 2 2 2 0 ABC transporter SRPRB PF09439.10 KXS20732.1 - 0.083 12.3 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_7 PF12775.7 KXS20732.1 - 0.2 11.2 0.0 0.35 10.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region ATP_bind_1 PF03029.17 KXS20732.1 - 0.22 11.3 0.0 0.29 10.9 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein MCM PF00493.23 KXS20732.1 - 0.23 10.5 0.0 0.35 9.9 0.0 1.2 1 0 0 1 1 1 0 MCM P-loop domain MFS_1 PF07690.16 KXS20733.1 - 9.6e-16 57.6 60.1 1.2e-10 40.9 51.3 3.0 2 1 0 2 2 2 2 Major Facilitator Superfamily SIR2_2 PF13289.6 KXS20734.1 - 2.2e-13 50.6 0.0 5.2e-13 49.3 0.1 1.5 2 0 0 2 2 2 1 SIR2-like domain Cu-oxidase PF00394.22 KXS20736.1 - 0.11 12.6 0.1 0.2 11.8 0.1 1.4 1 0 0 1 1 1 0 Multicopper oxidase Presenilin PF01080.17 KXS20736.1 - 2.1 7.0 7.8 2.5 6.8 7.8 1.0 1 0 0 1 1 1 0 Presenilin DNA_ligase_A_M PF01068.21 KXS20737.1 - 3.7e-66 222.7 0.1 6.3e-66 221.9 0.1 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KXS20737.1 - 6.9e-49 166.5 0.2 1.2e-48 165.7 0.2 1.4 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 KXS20737.1 - 7.5e-27 93.8 0.0 2.4e-26 92.2 0.0 1.9 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region eIF-3c_N PF05470.12 KXS20737.1 - 0.027 12.8 0.1 0.041 12.2 0.1 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Vpu PF00558.19 KXS20737.1 - 0.057 13.2 0.5 13 5.6 0.0 2.5 2 0 0 2 2 2 0 Vpu protein LRR_6 PF13516.6 KXS20742.1 - 2.2e-20 70.9 10.7 0.0015 18.4 0.1 9.3 9 0 0 9 9 9 6 Leucine Rich repeat cNMP_binding PF00027.29 KXS20742.1 - 1.8e-19 69.6 0.2 4.4e-19 68.3 0.2 1.7 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain LRR_4 PF12799.7 KXS20742.1 - 1.8e-15 56.8 4.7 0.001 19.4 0.0 5.2 5 0 0 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KXS20742.1 - 4.9e-10 38.5 13.3 19 6.3 0.1 9.8 10 0 0 10 10 10 3 Leucine Rich Repeat LRR_8 PF13855.6 KXS20742.1 - 0.002 17.9 6.0 0.73 9.6 0.5 4.0 4 1 0 4 4 4 2 Leucine rich repeat LEA_4 PF02987.16 KXS20742.1 - 0.024 14.7 0.8 0.04 14.0 0.8 1.3 1 0 0 1 1 1 0 Late embryogenesis abundant protein F-box PF00646.33 KXS20742.1 - 0.22 11.4 0.0 0.22 11.4 0.0 2.6 3 0 0 3 3 3 0 F-box domain Glyco_hydro_26 PF02156.15 KXS20743.1 - 7.3e-09 35.5 2.4 6.2e-07 29.1 2.4 2.2 1 1 0 1 1 1 1 Glycosyl hydrolase family 26 EF-hand_5 PF13202.6 KXS20743.1 - 0.015 14.7 0.1 0.03 13.8 0.1 1.5 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.6 KXS20743.1 - 0.23 11.5 0.5 0.46 10.6 0.5 1.5 1 0 0 1 1 1 0 EF-hand domain DUF4337 PF14235.6 KXS20744.1 - 0.39 10.8 4.2 0.45 10.6 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) EGF_2 PF07974.13 KXS20745.1 - 0.0046 17.3 1.3 0.0097 16.3 1.3 1.5 1 0 0 1 1 1 1 EGF-like domain Neurensin PF14927.6 KXS20745.1 - 0.039 13.7 0.0 0.059 13.1 0.0 1.3 1 0 0 1 1 1 0 Neurensin Aa_trans PF01490.18 KXS20746.1 - 1.9e-08 33.5 0.0 3.1e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Cadherin_C_2 PF16492.5 KXS20746.1 - 0.14 13.0 0.1 0.45 11.3 0.1 1.8 1 1 0 1 1 1 0 Cadherin cytoplasmic C-terminal S_4TM PF18159.1 KXS20746.1 - 2 7.7 5.3 20 4.4 0.0 2.1 2 0 0 2 2 2 0 SMODS-associating 4TM effector domain Aa_trans PF01490.18 KXS20747.1 - 1.6e-29 102.9 5.4 3.5e-28 98.5 5.4 2.0 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Fungal_trans PF04082.18 KXS20749.1 - 6.7e-14 51.5 0.2 1.5e-13 50.4 0.2 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Methyltransf_16 PF10294.9 KXS20750.1 - 2.2e-18 66.6 0.0 3.4e-16 59.5 0.0 2.3 1 1 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 KXS20750.1 - 0.16 11.3 0.0 0.26 10.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) LRR_4 PF12799.7 KXS20751.1 - 2.4e-05 24.6 8.3 0.49 10.9 1.4 4.2 4 0 0 4 4 4 3 Leucine Rich repeats (2 copies) TMEM154 PF15102.6 KXS20751.1 - 0.00032 20.6 0.3 0.00061 19.7 0.3 1.4 1 0 0 1 1 1 1 TMEM154 protein family Podoplanin PF05808.11 KXS20751.1 - 0.0033 17.5 1.4 0.0059 16.7 1.4 1.4 1 0 0 1 1 1 1 Podoplanin AJAP1_PANP_C PF15298.6 KXS20751.1 - 0.016 15.4 4.2 0.033 14.4 4.2 1.5 1 0 0 1 1 1 0 AJAP1/PANP C-terminus Rax2 PF12768.7 KXS20751.1 - 0.02 14.4 0.1 0.034 13.6 0.1 1.3 1 0 0 1 1 1 0 Cortical protein marker for cell polarity LRR_8 PF13855.6 KXS20751.1 - 0.028 14.2 4.5 3.3 7.5 0.1 3.4 3 0 0 3 3 3 0 Leucine rich repeat SCF PF02404.15 KXS20751.1 - 0.26 10.6 1.4 0.43 9.9 1.4 1.2 1 0 0 1 1 1 0 Stem cell factor SSP160 PF06933.11 KXS20751.1 - 7.8 4.6 24.6 0.26 9.4 18.7 1.4 2 0 0 2 2 2 0 Special lobe-specific silk protein SSP160 Hist_deacetyl PF00850.19 KXS20752.1 - 1.4e-57 195.5 0.0 1.8e-57 195.2 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain VSG_B PF13206.6 KXS20752.1 - 0.15 11.3 0.2 0.2 10.9 0.2 1.1 1 0 0 1 1 1 0 Trypanosomal VSG domain bZIP_2 PF07716.15 KXS20753.1 - 2.5e-08 33.9 4.3 2.5e-08 33.9 4.3 2.0 2 1 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 KXS20753.1 - 2.5e-07 30.7 6.5 2.5e-07 30.7 6.5 2.2 2 1 1 3 3 3 1 bZIP transcription factor bZIP_Maf PF03131.17 KXS20753.1 - 0.02 15.4 5.6 0.02 15.4 5.6 2.1 2 0 0 2 2 2 0 bZIP Maf transcription factor Fez1 PF06818.15 KXS20753.1 - 0.14 12.6 3.5 0.25 11.7 3.5 1.4 1 0 0 1 1 1 0 Fez1 AFG1_ATPase PF03969.16 KXS20754.1 - 2.4e-68 230.7 0.1 2.5e-67 227.3 0.0 2.0 2 0 0 2 2 2 1 AFG1-like ATPase AAA_22 PF13401.6 KXS20754.1 - 0.0019 18.5 0.0 0.0045 17.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KXS20754.1 - 0.0032 17.9 0.0 0.043 14.2 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.6 KXS20754.1 - 0.0081 16.5 0.0 0.016 15.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KXS20754.1 - 0.045 13.8 0.0 0.2 11.7 0.0 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.6 KXS20754.1 - 0.1 12.3 0.1 1.1 9.0 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_7 PF12775.7 KXS20754.1 - 0.11 12.0 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region NACHT PF05729.12 KXS20754.1 - 0.19 11.6 0.0 0.38 10.7 0.0 1.6 1 1 0 1 1 1 0 NACHT domain Glyco_hydro_31 PF01055.26 KXS20755.1 - 4.9e-104 349.0 0.0 6.6e-104 348.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 KXS20755.1 - 2.3e-11 43.8 0.1 2.3e-11 43.8 0.1 2.6 3 0 0 3 3 3 1 Galactose mutarotase-like XPC-binding PF09280.11 KXS20756.1 - 0.047 13.4 0.0 0.12 12.1 0.0 1.6 2 0 0 2 2 2 0 XPC-binding domain HD PF01966.22 KXS20757.1 - 1.1e-06 28.9 0.2 1.5e-06 28.4 0.2 1.3 1 0 0 1 1 1 1 HD domain HD_4 PF13328.6 KXS20757.1 - 0.0054 16.5 0.1 0.009 15.8 0.1 1.4 1 1 0 1 1 1 1 HD domain HDOD PF08668.12 KXS20757.1 - 0.035 13.6 0.0 0.051 13.1 0.0 1.2 1 0 0 1 1 1 0 HDOD domain Cyclin_N PF00134.23 KXS20758.1 - 1.6e-33 115.2 0.1 2.3e-33 114.6 0.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain TNF PF00229.18 KXS20759.1 - 0.082 12.9 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 TNF(Tumour Necrosis Factor) family SNF2_N PF00176.23 KXS20760.1 - 1.4e-64 218.1 0.0 2.4e-64 217.3 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KXS20760.1 - 2.2e-12 47.3 0.0 3e-11 43.6 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.6 KXS20760.1 - 2e-05 24.5 2.1 4.5e-05 23.3 2.1 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KXS20760.1 - 7.1e-05 22.6 1.4 0.00017 21.4 1.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXS20760.1 - 0.0001 22.2 0.7 0.00025 21.0 0.7 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KXS20760.1 - 0.0008 19.2 2.0 0.0017 18.1 2.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KXS20760.1 - 0.00089 19.1 3.2 0.0022 17.8 3.3 1.6 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KXS20760.1 - 0.0058 16.9 1.8 0.016 15.5 1.8 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 KXS20760.1 - 0.0066 16.6 2.2 0.015 15.4 2.2 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 KXS20760.1 - 0.026 14.3 2.8 0.075 12.9 2.8 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 KXS20760.1 - 0.092 12.9 1.8 0.2 11.8 1.8 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 p450 PF00067.22 KXS20761.1 - 3.5e-62 210.7 0.0 5e-62 210.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_3 PF01494.19 KXS20762.1 - 5.5e-24 85.1 0.0 8.6e-24 84.4 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KXS20762.1 - 1.3e-06 28.3 0.1 0.001 18.8 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXS20762.1 - 0.00022 20.6 0.3 0.12 11.6 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXS20762.1 - 0.00044 20.4 0.1 0.0011 19.1 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KXS20762.1 - 0.0019 18.7 0.2 0.018 15.6 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 KXS20762.1 - 0.0034 16.5 0.0 0.01 14.9 0.0 1.8 1 1 0 1 1 1 1 Squalene epoxidase Trp_halogenase PF04820.14 KXS20762.1 - 0.053 12.4 1.4 5.3 5.8 0.0 2.2 1 1 0 2 2 2 0 Tryptophan halogenase 3HCDH_N PF02737.18 KXS20762.1 - 0.066 13.1 0.2 0.11 12.3 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 KXS20762.1 - 0.16 11.5 0.2 0.27 10.8 0.2 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.16 KXS20762.1 - 0.17 11.5 0.1 0.3 10.7 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA adh_short_C2 PF13561.6 KXS20763.1 - 1.4e-51 175.3 0.1 1.8e-51 175.0 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXS20763.1 - 2.8e-46 157.4 0.0 3.4e-46 157.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXS20763.1 - 6.4e-06 26.2 0.0 1.2e-05 25.3 0.0 1.4 1 1 0 1 1 1 1 KR domain MFS_2 PF13347.6 KXS20764.1 - 6.3e-07 28.3 12.9 7.4e-07 28.1 7.8 2.9 3 0 0 3 3 3 1 MFS/sugar transport protein TDA11 PF17084.5 KXS20764.1 - 0.12 11.3 3.3 0.2 10.6 3.3 1.2 1 0 0 1 1 1 0 Topoisomerase I damage affected protein 11 AAA_6 PF12774.7 KXS20765.1 - 7.5e-132 439.2 0.0 5.4e-129 429.9 0.0 3.0 2 1 0 2 2 1 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 KXS20765.1 - 1.2e-115 386.8 7.9 1.2e-115 386.8 7.9 4.2 4 1 0 4 4 3 1 Dynein heavy chain, N-terminal region 2 DHC_N1 PF08385.12 KXS20765.1 - 1.2e-112 377.5 0.0 1.2e-112 377.5 0.0 3.8 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 1 AAA_9 PF12781.7 KXS20765.1 - 1.4e-73 246.7 0.0 1.4e-73 246.7 0.0 3.6 3 0 0 3 3 2 1 ATP-binding dynein motor region AAA_8 PF12780.7 KXS20765.1 - 6.5e-69 232.1 0.0 2.1e-68 230.5 0.0 2.0 2 0 0 2 2 1 1 P-loop containing dynein motor region D4 MT PF12777.7 KXS20765.1 - 3.2e-48 164.5 5.6 7.6e-48 163.3 5.2 1.8 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_7 PF12775.7 KXS20765.1 - 2.4e-42 144.5 0.0 5.2e-35 120.6 0.0 5.0 5 0 0 5 5 4 2 P-loop containing dynein motor region AAA_5 PF07728.14 KXS20765.1 - 2.6e-39 134.4 0.0 4.8e-13 49.3 0.0 7.1 6 1 0 6 6 5 4 AAA domain (dynein-related subfamily) AAA_lid_11 PF18198.1 KXS20765.1 - 4.2e-36 124.2 0.0 1.1e-35 122.8 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 KXS20765.1 - 7e-30 103.6 0.0 1.9e-28 98.9 0.0 3.0 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain Dynein_C PF18199.1 KXS20765.1 - 3.1e-26 92.3 0.1 5.3e-24 85.0 0.0 3.5 2 1 1 3 3 3 1 Dynein heavy chain C-terminal domain Dynein_AAA_lid PF17852.1 KXS20765.1 - 3.4e-20 72.4 0.0 1.2e-19 70.7 0.0 2.0 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_22 PF13401.6 KXS20765.1 - 6.5e-17 62.1 8.4 0.0012 19.1 0.0 7.2 6 0 0 6 6 6 3 AAA domain AAA PF00004.29 KXS20765.1 - 9e-16 58.5 0.1 0.00067 20.1 0.0 5.9 6 0 0 6 6 5 2 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KXS20765.1 - 1.5e-10 41.4 0.3 0.055 13.6 0.0 4.9 4 0 0 4 4 4 3 AAA domain AAA_16 PF13191.6 KXS20765.1 - 5.6e-10 39.9 2.0 0.72 10.2 0.0 7.1 6 0 0 6 6 6 2 AAA ATPase domain AAA_18 PF13238.6 KXS20765.1 - 8.3e-10 39.3 3.2 0.069 13.7 0.0 5.4 5 0 0 5 5 4 2 AAA domain T2SSE PF00437.20 KXS20765.1 - 3.3e-07 29.7 0.0 0.017 14.2 0.0 3.6 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_lid_1 PF17857.1 KXS20765.1 - 1e-06 28.8 0.2 5.4e-05 23.3 0.0 3.6 3 0 0 3 3 3 1 AAA+ lid domain AAA_19 PF13245.6 KXS20765.1 - 2.3e-06 28.0 0.1 0.061 13.6 0.0 4.7 4 0 0 4 4 4 1 AAA domain ABC_tran PF00005.27 KXS20765.1 - 4e-06 27.4 0.0 1.6 9.3 0.0 4.3 3 0 0 3 3 3 2 ABC transporter AAA_29 PF13555.6 KXS20765.1 - 8.1e-06 25.5 0.1 0.92 9.3 0.0 3.7 3 0 0 3 3 3 2 P-loop containing region of AAA domain Mg_chelatase PF01078.21 KXS20765.1 - 2.5e-05 23.8 0.9 0.92 8.9 0.0 3.8 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI FtsK_SpoIIIE PF01580.18 KXS20765.1 - 0.00016 21.1 0.0 1.3 8.4 0.0 3.8 3 0 0 3 3 3 1 FtsK/SpoIIIE family AAA_30 PF13604.6 KXS20765.1 - 0.00018 21.3 0.9 13 5.4 0.0 4.5 4 0 0 4 4 4 0 AAA domain AAA_25 PF13481.6 KXS20765.1 - 0.00047 19.8 2.9 0.1 12.1 0.0 4.6 5 0 0 5 5 4 1 AAA domain AAA_24 PF13479.6 KXS20765.1 - 0.00063 19.5 0.1 40 3.9 0.0 5.0 4 0 0 4 4 4 0 AAA domain IstB_IS21 PF01695.17 KXS20765.1 - 0.00089 19.0 0.4 0.45 10.2 0.0 4.1 4 0 0 4 4 4 1 IstB-like ATP binding protein DUF3450 PF11932.8 KXS20765.1 - 0.0024 17.2 1.5 0.0024 17.2 1.5 3.1 3 0 0 3 3 1 1 Protein of unknown function (DUF3450) RuvB_N PF05496.12 KXS20765.1 - 0.0055 16.5 1.5 3.4 7.4 0.0 4.4 4 0 0 4 4 4 1 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 KXS20765.1 - 0.0083 16.5 0.0 8.2 6.9 0.0 4.4 4 0 0 4 4 4 0 RNA helicase Rad17 PF03215.15 KXS20765.1 - 0.012 15.6 0.1 25 4.7 0.0 4.0 4 0 0 4 4 3 0 Rad17 P-loop domain AAA_21 PF13304.6 KXS20765.1 - 0.014 15.2 0.3 13 5.5 0.0 3.6 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system Guanylate_kin PF00625.21 KXS20765.1 - 0.024 14.3 0.2 5.7 6.6 0.0 3.5 3 0 0 3 3 2 0 Guanylate kinase PduV-EutP PF10662.9 KXS20765.1 - 0.035 13.8 0.2 15 5.3 0.1 3.4 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation TsaE PF02367.17 KXS20765.1 - 0.058 13.4 0.8 18 5.4 0.0 3.7 4 0 0 4 4 4 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 KXS20765.1 - 0.059 13.3 4.5 49 3.8 0.0 5.1 5 0 0 5 5 4 0 NACHT domain cobW PF02492.19 KXS20765.1 - 0.076 12.6 0.8 12 5.4 0.0 3.4 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain Pox_A32 PF04665.12 KXS20765.1 - 0.096 12.1 0.2 27 4.1 0.0 3.3 3 0 0 3 3 3 0 Poxvirus A32 protein DEAD PF00270.29 KXS20765.1 - 0.098 12.4 0.0 16 5.2 0.0 3.2 3 0 0 3 3 3 0 DEAD/DEAH box helicase MbeB_N PF04837.12 KXS20765.1 - 0.26 11.6 1.1 1.2 9.5 0.1 2.7 2 0 0 2 2 1 0 MbeB-like, N-term conserved region G-alpha PF00503.20 KXS20765.1 - 0.62 9.2 5.0 20 4.2 1.8 4.2 3 1 0 3 3 3 0 G-protein alpha subunit SRP54 PF00448.22 KXS20765.1 - 1 9.0 5.0 14 5.2 0.0 3.8 5 0 0 5 5 3 0 SRP54-type protein, GTPase domain TelA PF05816.11 KXS20765.1 - 1.1 8.2 10.8 0.022 13.8 0.3 3.1 2 0 0 2 2 1 0 Toxic anion resistance protein (TelA) DUF948 PF06103.11 KXS20765.1 - 3 8.2 10.1 16 5.8 0.7 5.2 4 0 0 4 4 3 0 Bacterial protein of unknown function (DUF948) 2-Hacid_dh_C PF02826.19 KXS20766.1 - 8.3e-41 139.3 0.0 1.5e-40 138.5 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KXS20766.1 - 5.5e-05 22.8 0.1 0.00012 21.7 0.0 1.6 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KXS20766.1 - 0.00081 19.6 0.0 0.0032 17.7 0.0 1.9 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase XdhC_C PF13478.6 KXS20766.1 - 0.0029 18.1 0.0 0.012 16.1 0.0 2.0 2 1 0 2 2 2 1 XdhC Rossmann domain AdoHcyase_NAD PF00670.21 KXS20766.1 - 0.026 14.6 0.0 0.057 13.5 0.0 1.5 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain COesterase PF00135.28 KXS20767.1 - 9.2e-12 44.6 0.7 2.4e-11 43.2 0.7 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXS20767.1 - 4.2e-10 39.8 1.8 5.4e-09 36.2 0.3 2.3 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KXS20767.1 - 0.028 13.9 0.0 0.044 13.2 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF2244 PF10003.9 KXS20767.1 - 0.97 9.1 7.2 0.075 12.7 1.3 2.1 3 0 0 3 3 3 0 Integral membrane protein (DUF2244) RGS PF00615.19 KXS20768.1 - 1.5e-08 34.9 0.3 3.3e-08 33.8 0.3 1.5 1 0 0 1 1 1 1 Regulator of G protein signaling domain OST3_OST6 PF04756.13 KXS20769.1 - 4.3e-84 282.3 0.1 6.2e-84 281.8 0.1 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin PF00085.20 KXS20769.1 - 0.14 12.2 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin DUF3429 PF11911.8 KXS20769.1 - 0.6 10.4 7.8 0.44 10.8 5.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3429) Renin_r PF07850.14 KXS20769.1 - 1.6 9.4 6.9 0.79 10.4 0.1 2.7 2 1 1 3 3 3 0 Renin receptor-like protein Aa_trans PF01490.18 KXS20771.1 - 8.8e-63 212.4 13.8 1.1e-62 212.1 13.8 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KXS20771.1 - 0.00045 19.4 9.1 0.00045 19.4 9.1 2.8 2 1 0 3 3 3 2 Tryptophan/tyrosine permease family 6PGD PF00393.19 KXS20772.1 - 3e-127 423.9 0.0 4.3e-127 423.4 0.0 1.2 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 KXS20772.1 - 7.6e-50 169.2 0.0 1.4e-49 168.3 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KXS20772.1 - 0.0032 18.0 0.1 0.0077 16.8 0.0 1.7 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent WD40 PF00400.32 KXS20773.1 - 1.6e-44 149.0 38.0 9.6e-06 26.3 0.1 12.6 12 1 0 12 12 12 9 WD domain, G-beta repeat Utp13 PF08625.11 KXS20773.1 - 5.2e-27 94.5 0.0 8.6e-27 93.8 0.0 1.4 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain ANAPC4_WD40 PF12894.7 KXS20773.1 - 1.2e-08 35.1 1.5 0.093 13.0 0.0 5.9 6 1 0 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KXS20773.1 - 7.5e-05 21.8 0.8 20 4.0 0.1 5.7 3 1 3 6 6 6 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 KXS20773.1 - 0.0036 15.9 0.1 0.14 10.7 0.0 2.2 2 0 0 2 2 2 1 Cytochrome D1 heme domain Nup160 PF11715.8 KXS20773.1 - 0.0053 15.5 19.9 1.6 7.3 0.1 6.4 6 2 2 8 8 8 4 Nucleoporin Nup120/160 Nbas_N PF15492.6 KXS20773.1 - 0.02 14.2 2.7 24 4.1 0.0 4.9 5 2 2 7 7 7 0 Neuroblastoma-amplified sequence, N terminal Hira PF07569.11 KXS20773.1 - 0.022 14.5 1.6 7.2 6.3 0.0 3.8 4 0 0 4 4 4 0 TUP1-like enhancer of split Glyco_transf_36 PF06165.11 KXS20774.1 - 0.074 12.4 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 36 Pox_VP8_L4R PF04498.12 KXS20774.1 - 0.18 11.4 0.0 0.25 10.9 0.0 1.2 1 0 0 1 1 1 0 Poxvirus nucleic acid binding protein VP8/L4R LRR_8 PF13855.6 KXS20776.1 - 5.3e-10 38.9 3.9 0.1 12.4 1.1 4.5 2 2 2 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 KXS20776.1 - 1.6e-09 37.9 17.5 0.021 15.2 0.5 5.4 4 1 1 5 5 5 4 Leucine Rich repeats (2 copies) SH3_1 PF00018.28 KXS20776.1 - 8.6e-05 22.1 0.0 0.00018 21.1 0.0 1.5 1 0 0 1 1 1 1 SH3 domain LRR_6 PF13516.6 KXS20776.1 - 0.012 15.7 1.8 3.9 7.8 0.3 4.2 4 0 0 4 4 4 0 Leucine Rich repeat SKG6 PF08693.10 KXS20776.1 - 0.16 11.4 0.6 0.34 10.3 0.6 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain ADH_zinc_N PF00107.26 KXS20778.1 - 2.9e-10 40.2 0.2 5.6e-10 39.3 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXS20778.1 - 1e-07 33.1 0.0 1.9e-07 32.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXS20778.1 - 0.00011 22.0 0.0 0.00019 21.3 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AMP-binding PF00501.28 KXS20779.1 - 6.3e-85 285.3 0.0 8.6e-85 284.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXS20779.1 - 2.2e-21 76.6 0.1 7.1e-21 75.0 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DUF2798 PF11391.8 KXS20779.1 - 0.29 11.2 1.1 0.61 10.2 1.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2798) adh_short PF00106.25 KXS20781.1 - 2.9e-26 92.2 0.1 9.1e-24 84.0 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXS20781.1 - 1.2e-14 54.4 0.0 1.8e-14 53.9 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXS20781.1 - 5.8e-06 26.3 0.0 8.9e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXS20781.1 - 0.09 12.2 0.0 0.13 11.7 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Abhydrolase_6 PF12697.7 KXS20782.1 - 4.9e-08 33.8 1.2 8.9e-08 33.0 1.2 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 KXS20782.1 - 0.0037 17.2 0.0 0.0058 16.5 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KXS20782.1 - 0.0068 15.9 0.0 2.7 7.4 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family adh_short PF00106.25 KXS20783.1 - 2.1e-40 138.3 0.1 3.2e-40 137.7 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXS20783.1 - 3.3e-26 92.3 0.1 4.8e-26 91.7 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXS20783.1 - 6e-08 32.8 0.1 8.8e-08 32.3 0.1 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KXS20783.1 - 0.0061 16.5 0.1 0.018 15.0 0.1 1.8 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KXS20783.1 - 0.057 12.9 0.0 0.11 11.9 0.0 1.6 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KXS20783.1 - 0.069 13.4 0.4 0.22 11.8 0.1 2.0 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Wax2_C PF12076.8 KXS20783.1 - 0.079 12.7 0.1 0.079 12.7 0.1 1.8 2 0 0 2 2 2 0 WAX2 C-terminal domain Abhydrolase_6 PF12697.7 KXS20784.1 - 4.2e-06 27.5 0.5 7.3e-06 26.7 0.5 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXS20784.1 - 0.071 12.4 0.0 0.096 11.9 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KXS20784.1 - 0.094 12.3 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 KXS20784.1 - 0.1 12.4 0.1 0.15 11.9 0.1 1.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold HSF_DNA-bind PF00447.17 KXS20785.1 - 5.6e-27 94.2 0.0 6e-27 94.1 0.0 1.0 1 0 0 1 1 1 1 HSF-type DNA-binding DENN PF02141.21 KXS20787.1 - 7.2e-29 101.1 0.0 1.5e-28 100.0 0.0 1.5 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 KXS20787.1 - 2.5e-10 41.0 2.3 6e-10 39.7 2.3 1.7 1 0 0 1 1 1 1 uDENN domain FAD_binding_3 PF01494.19 KXS20788.1 - 1e-13 51.3 0.0 1.1e-06 28.2 0.0 2.0 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 KXS20788.1 - 5.9e-07 29.0 0.1 0.0025 17.1 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXS20788.1 - 1.6e-06 27.1 0.1 0.00049 18.9 0.1 2.0 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox PF00070.27 KXS20788.1 - 0.00043 20.8 0.0 0.49 11.0 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXS20788.1 - 0.00076 18.8 0.1 0.067 12.4 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXS20788.1 - 0.0011 18.1 0.0 0.0027 16.8 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.22 KXS20788.1 - 0.0023 17.1 0.0 0.0024 17.0 0.0 1.3 1 1 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 KXS20788.1 - 0.0035 17.5 0.0 0.0088 16.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 KXS20788.1 - 0.014 14.3 0.3 0.29 9.9 0.3 2.0 2 0 0 2 2 2 0 Tryptophan halogenase Glu_dehyd_C PF16912.5 KXS20788.1 - 0.081 12.4 0.0 1.4 8.3 0.0 2.1 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus FAD_oxidored PF12831.7 KXS20788.1 - 0.1 11.9 0.3 0.17 11.2 0.1 1.4 2 0 0 2 2 2 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KXS20788.1 - 0.13 11.3 0.1 0.22 10.5 0.1 1.4 2 0 0 2 2 2 0 Lycopene cyclase protein FAA_hydrolase PF01557.18 KXS20789.1 - 0.0039 16.9 0.0 0.0075 16.0 0.0 1.4 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Mito_carr PF00153.27 KXS20790.1 - 1.1e-61 204.8 0.1 3.9e-19 68.4 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein ATG16 PF08614.11 KXS20791.1 - 1.1e-07 32.3 2.3 1.1e-07 32.3 2.3 1.7 2 0 0 2 2 1 1 Autophagy protein 16 (ATG16) DUF812 PF05667.11 KXS20791.1 - 0.00038 19.5 0.6 0.0005 19.1 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) FPP PF05911.11 KXS20791.1 - 0.00068 18.0 3.9 0.001 17.4 3.9 1.2 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil Wtap PF17098.5 KXS20791.1 - 0.0027 17.7 2.4 0.0042 17.0 2.4 1.3 1 0 0 1 1 1 1 WTAP/Mum2p family Filament PF00038.21 KXS20791.1 - 0.0037 16.9 6.5 0.0059 16.2 6.5 1.2 1 0 0 1 1 1 1 Intermediate filament protein Cnn_1N PF07989.11 KXS20791.1 - 0.0042 17.2 9.0 0.17 12.1 1.1 2.5 1 1 1 2 2 2 2 Centrosomin N-terminal motif 1 MscS_porin PF12795.7 KXS20791.1 - 0.0045 16.6 10.8 0.0081 15.7 10.8 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain HOOK PF05622.12 KXS20791.1 - 0.0057 14.9 11.1 0.0084 14.3 11.1 1.1 1 0 0 1 1 1 1 HOOK protein DUF4201 PF13870.6 KXS20791.1 - 0.0063 16.3 9.9 0.0099 15.6 9.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) APG6_N PF17675.1 KXS20791.1 - 0.0064 17.0 8.8 0.011 16.3 8.8 1.3 1 0 0 1 1 1 1 Apg6 coiled-coil region PRKG1_interact PF15898.5 KXS20791.1 - 0.007 17.2 9.2 0.015 16.2 9.2 1.5 1 0 0 1 1 1 1 cGMP-dependent protein kinase interacting domain Spc7 PF08317.11 KXS20791.1 - 0.0076 15.2 8.5 0.011 14.6 8.5 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein UPF0242 PF06785.11 KXS20791.1 - 0.0076 16.4 6.5 0.013 15.6 6.5 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus Fib_alpha PF08702.10 KXS20791.1 - 0.0085 16.3 4.8 0.015 15.5 4.8 1.3 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family SHE3 PF17078.5 KXS20791.1 - 0.0094 15.7 7.8 0.015 15.1 7.8 1.2 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 Leu_zip PF15294.6 KXS20791.1 - 0.011 15.3 8.7 0.015 14.8 8.7 1.1 1 0 0 1 1 1 0 Leucine zipper WEMBL PF05701.11 KXS20791.1 - 0.013 14.3 7.0 0.02 13.6 7.0 1.2 1 0 0 1 1 1 0 Weak chloroplast movement under blue light HemX PF04375.14 KXS20791.1 - 0.013 14.8 5.5 0.02 14.2 5.5 1.2 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase Bacillus_HBL PF05791.11 KXS20791.1 - 0.015 15.1 1.1 0.024 14.5 1.1 1.2 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) Mod_r PF07200.13 KXS20791.1 - 0.029 14.5 6.4 0.053 13.6 6.4 1.4 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Atg14 PF10186.9 KXS20791.1 - 0.048 12.8 7.6 0.1 11.7 7.6 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Phage_HK97_TLTM PF06120.11 KXS20791.1 - 0.051 12.8 2.2 0.079 12.1 2.2 1.2 1 0 0 1 1 1 0 Tail length tape measure protein COG5 PF10392.9 KXS20791.1 - 0.059 13.5 1.0 0.11 12.7 1.0 1.3 1 0 0 1 1 1 0 Golgi transport complex subunit 5 CENP-H PF05837.12 KXS20791.1 - 0.085 13.3 10.6 0.17 12.3 10.6 1.4 1 0 0 1 1 1 0 Centromere protein H (CENP-H) FAM76 PF16046.5 KXS20791.1 - 0.095 12.0 0.2 0.15 11.4 0.2 1.3 1 0 0 1 1 1 0 FAM76 protein MbeD_MobD PF04899.12 KXS20791.1 - 0.1 12.7 4.9 0.45 10.7 0.5 2.4 2 0 0 2 2 2 0 MbeD/MobD like Fez1 PF06818.15 KXS20791.1 - 0.11 12.9 9.0 0.18 12.2 9.0 1.3 1 0 0 1 1 1 0 Fez1 DUF4407 PF14362.6 KXS20791.1 - 0.11 11.8 5.0 0.17 11.2 5.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Herpes_UL6 PF01763.16 KXS20791.1 - 0.14 10.6 0.7 0.2 10.1 0.7 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like bZIP_1 PF00170.21 KXS20791.1 - 0.17 12.0 13.2 0.035 14.2 7.4 2.5 1 1 0 2 2 2 0 bZIP transcription factor Phage_GP20 PF06810.11 KXS20791.1 - 0.17 11.7 9.4 1.3 8.9 8.6 2.3 2 1 0 2 2 2 0 Phage minor structural protein GP20 AAA_13 PF13166.6 KXS20791.1 - 0.21 10.2 3.5 0.29 9.7 3.5 1.1 1 0 0 1 1 1 0 AAA domain Golgin_A5 PF09787.9 KXS20791.1 - 0.25 10.8 8.9 0.39 10.2 8.9 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 Snapin_Pallidin PF14712.6 KXS20791.1 - 0.26 11.8 9.7 0.57 10.6 9.7 1.6 1 0 0 1 1 1 0 Snapin/Pallidin Exonuc_VII_L PF02601.15 KXS20791.1 - 0.29 10.7 2.9 0.43 10.1 2.9 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit APC_N_CC PF16689.5 KXS20791.1 - 0.31 11.1 9.2 1.2 9.3 9.2 1.9 1 1 0 1 1 1 0 Coiled-coil N-terminus of APC, dimerisation domain SlyX PF04102.12 KXS20791.1 - 0.39 11.4 17.1 0.061 14.0 4.4 3.0 2 1 1 3 3 2 0 SlyX DUF4200 PF13863.6 KXS20791.1 - 0.47 10.9 13.6 0.75 10.2 13.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) I_LWEQ PF01608.17 KXS20791.1 - 0.53 10.5 5.1 0.98 9.7 5.1 1.3 1 0 0 1 1 1 0 I/LWEQ domain Jnk-SapK_ap_N PF09744.9 KXS20791.1 - 0.58 10.4 11.8 1 9.6 11.8 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 TMPIT PF07851.13 KXS20791.1 - 0.58 9.4 4.6 0.8 8.9 4.6 1.1 1 0 0 1 1 1 0 TMPIT-like protein EzrA PF06160.12 KXS20791.1 - 0.67 8.1 10.0 0.97 7.5 10.0 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA DUF16 PF01519.16 KXS20791.1 - 0.71 10.4 7.6 2.2 8.8 7.6 1.7 1 1 0 1 1 1 0 Protein of unknown function DUF16 DUF724 PF05266.14 KXS20791.1 - 0.81 9.5 6.6 1.5 8.6 6.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Phage_GPO PF05929.11 KXS20791.1 - 0.89 9.1 6.0 1.5 8.4 6.0 1.4 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF1664 PF07889.12 KXS20791.1 - 0.9 9.6 6.1 1.5 8.8 6.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF4446 PF14584.6 KXS20791.1 - 1.1 9.2 4.3 1.9 8.4 4.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) DUF2203 PF09969.9 KXS20791.1 - 1.2 9.8 6.3 3 8.6 6.3 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) DivIC PF04977.15 KXS20791.1 - 1.4 8.8 15.2 0.97 9.2 0.7 3.0 1 1 2 3 3 3 0 Septum formation initiator DivIVA PF05103.13 KXS20791.1 - 1.4 9.0 8.5 6.1 6.9 8.5 1.9 1 1 0 1 1 1 0 DivIVA protein GAS PF13851.6 KXS20791.1 - 1.5 8.1 15.4 4.7 6.5 15.5 1.6 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding TPR_MLP1_2 PF07926.12 KXS20791.1 - 1.7 8.7 14.9 1 9.4 12.5 1.8 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein ADIP PF11559.8 KXS20791.1 - 1.7 8.7 15.4 3 7.9 15.4 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding CENP-F_leu_zip PF10473.9 KXS20791.1 - 1.7 8.6 17.1 5 7.2 17.1 1.7 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FlaC_arch PF05377.11 KXS20791.1 - 2 8.9 10.0 9.4 6.7 4.5 2.8 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) Nup188_C PF18378.1 KXS20791.1 - 2.2 7.0 4.8 3.1 6.6 4.8 1.1 1 0 0 1 1 1 0 Nuclear pore protein NUP188 C-terminal domain OmpH PF03938.14 KXS20791.1 - 2.3 8.6 9.3 5.8 7.3 9.3 1.6 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) NPV_P10 PF05531.12 KXS20791.1 - 4.2 7.9 4.5 30 5.2 0.6 2.4 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Tho2 PF11262.8 KXS20791.1 - 4.4 6.4 5.4 6.5 5.9 5.4 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 BLOC1_2 PF10046.9 KXS20791.1 - 4.7 7.6 8.3 11 6.4 6.5 1.8 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DASH_Spc19 PF08287.11 KXS20791.1 - 6 6.7 13.6 14 5.5 13.6 1.6 1 0 0 1 1 1 0 Spc19 YlqD PF11068.8 KXS20791.1 - 7.1 7.0 10.2 14 6.1 10.2 1.4 1 0 0 1 1 1 0 YlqD protein S10_plectin PF03501.15 KXS20792.1 - 2.3e-43 146.2 1.7 2.8e-43 145.9 1.7 1.1 1 0 0 1 1 1 1 Plectin/S10 domain SurE PF01975.17 KXS20794.1 - 1.2e-45 155.7 0.0 1.5e-45 155.4 0.0 1.1 1 0 0 1 1 1 1 Survival protein SurE RPE65 PF03055.15 KXS20795.1 - 5.6e-06 25.8 0.0 7.8e-06 25.3 0.0 1.1 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein adh_short_C2 PF13561.6 KXS20796.1 - 6.5e-77 258.2 0.3 7.3e-77 258.1 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXS20796.1 - 1.3e-20 73.7 0.1 1.8e-20 73.2 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Enoyl_reductase PF12241.8 KXS20796.1 - 0.00021 20.7 0.3 0.14 11.5 0.0 2.2 1 1 0 2 2 2 2 Trans-2-enoyl-CoA reductase catalytic region adh_short_C2 PF13561.6 KXS20797.1 - 3.7e-76 255.8 0.6 4.2e-76 255.6 0.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXS20797.1 - 8.1e-21 74.4 0.1 1.1e-20 74.0 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Enoyl_reductase PF12241.8 KXS20797.1 - 0.00094 18.6 0.5 0.48 9.7 0.0 2.2 1 1 1 2 2 2 2 Trans-2-enoyl-CoA reductase catalytic region HMMR_C PF15908.5 KXS20798.1 - 3.3e-08 33.9 12.5 3.3e-08 33.9 12.5 7.4 4 2 2 7 7 7 1 Hyaluronan mediated motility receptor C-terminal DUF1664 PF07889.12 KXS20798.1 - 0.013 15.5 2.7 0.013 15.5 2.7 8.5 2 2 7 10 10 10 0 Protein of unknown function (DUF1664) CLZ PF16526.5 KXS20798.1 - 0.019 15.3 6.2 0.019 15.3 6.2 8.5 4 3 4 8 8 8 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF919 PF06034.11 KXS20798.1 - 0.15 11.9 0.1 0.15 11.9 0.1 4.7 5 0 0 5 5 5 0 Nucleopolyhedrovirus protein of unknown function (DUF919) LKAAEAR PF15478.6 KXS20800.1 - 2.2e-05 24.8 0.9 3.4e-05 24.1 0.9 1.4 1 0 0 1 1 1 1 Family of unknown function with LKAAEAR motif Ribosomal_60s PF00428.19 KXS20800.1 - 8 7.1 9.3 1.6 9.4 1.5 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein MFS_1 PF07690.16 KXS20801.1 - 5.3e-34 117.7 29.9 5.3e-34 117.7 29.9 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.16 KXS20802.1 - 1.5e-30 106.3 31.0 1.5e-30 106.3 31.0 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF2937 PF11157.8 KXS20802.1 - 0.89 9.3 3.1 0.31 10.7 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) zf-RING_2 PF13639.6 KXS20803.1 - 1.5e-12 47.6 5.2 3.3e-12 46.5 5.2 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KXS20803.1 - 3.1e-09 36.5 4.4 6.3e-09 35.5 4.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXS20803.1 - 2.7e-08 33.5 3.2 5e-08 32.7 3.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KXS20803.1 - 4.8e-07 29.4 1.5 4.8e-07 29.4 1.5 1.9 2 0 0 2 2 2 1 RING-like zinc finger zf-rbx1 PF12678.7 KXS20803.1 - 2.1e-06 27.9 8.9 1.1e-05 25.7 8.9 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KXS20803.1 - 6.5e-06 26.0 3.4 1.2e-05 25.2 3.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KXS20803.1 - 4.7e-05 23.3 2.6 5.2e-05 23.2 0.8 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 KXS20803.1 - 0.00045 20.2 1.3 0.0012 18.8 1.3 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 KXS20803.1 - 0.0052 16.4 3.1 0.011 15.3 3.1 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-Di19 PF05605.12 KXS20803.1 - 0.0072 16.6 1.0 4.6 7.6 0.1 2.5 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding RINGv PF12906.7 KXS20803.1 - 0.011 15.8 4.6 0.033 14.3 3.4 2.2 2 0 0 2 2 2 0 RING-variant domain FANCL_C PF11793.8 KXS20803.1 - 0.014 15.6 5.8 0.1 12.8 5.8 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_3 PF13920.6 KXS20803.1 - 0.02 14.8 2.3 0.04 13.8 2.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KXS20803.1 - 0.026 14.4 8.9 0.21 11.5 3.2 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 KXS20803.1 - 0.033 14.0 2.4 0.1 12.4 2.4 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 KXS20803.1 - 0.046 13.9 2.8 0.13 12.5 2.8 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING PHD PF00628.29 KXS20803.1 - 0.054 13.4 3.1 0.12 12.3 3.1 1.7 1 0 0 1 1 1 0 PHD-finger zf-RING-like PF08746.11 KXS20803.1 - 0.69 10.3 4.5 2 8.8 4.6 1.8 1 1 0 1 1 1 0 RING-like domain Chlam_OMP PF01308.17 KXS20805.1 - 0.14 10.9 0.0 0.19 10.5 0.0 1.1 1 0 0 1 1 1 0 Chlamydia major outer membrane protein Glyco_trans_2_3 PF13632.6 KXS20806.1 - 4.4e-08 33.3 2.7 4.4e-08 33.3 2.7 2.1 2 0 0 2 2 2 1 Glycosyl transferase family group 2 BIV_Env PF05858.12 KXS20806.1 - 0.42 8.7 1.5 0.64 8.1 1.5 1.1 1 0 0 1 1 1 0 Bovine immunodeficiency virus surface protein (SU) API5 PF05918.11 KXS20809.1 - 1.4e-14 53.8 0.0 2.9e-14 52.8 0.0 1.4 1 1 0 1 1 1 1 Apoptosis inhibitory protein 5 (API5) WD40 PF00400.32 KXS20810.1 - 1.2e-35 120.9 9.0 2.7e-06 28.0 0.0 8.2 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXS20810.1 - 7.6e-12 45.4 0.2 0.0076 16.5 0.0 4.4 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KXS20810.1 - 6.6e-05 21.7 0.2 7.5 5.1 0.0 4.8 2 2 4 6 6 6 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KXS20810.1 - 0.0016 17.5 4.7 5.8 5.8 0.0 4.9 1 1 3 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KXS20810.1 - 0.12 11.7 0.0 14 4.9 0.0 2.8 1 1 1 3 3 3 0 WD40-like domain PALB2_WD40 PF16756.5 KXS20810.1 - 0.22 10.4 0.1 0.22 10.4 0.1 3.2 1 1 4 5 5 5 0 Partner and localizer of BRCA2 WD40 domain MMtag PF10159.9 KXS20811.1 - 2.4e-31 107.9 1.6 2.4e-31 107.9 1.6 4.3 3 1 3 6 6 6 1 Multiple myeloma tumor-associated Peptidase_S49_N PF08496.10 KXS20811.1 - 6.2 6.9 11.1 22 5.1 11.1 1.9 1 0 0 1 1 1 0 Peptidase family S49 N-terminal CAP_N PF01213.19 KXS20812.1 - 4.8 6.6 8.4 6.2 6.2 8.4 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DEC-1_N PF04625.13 KXS20812.1 - 5.5 5.9 11.6 5.7 5.8 11.6 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Iwr1 PF08574.10 KXS20813.1 - 1.1e-09 39.1 2.2 1.1e-09 39.1 2.2 5.3 4 1 1 5 5 5 1 Transcription factor Iwr1 CENP-B_dimeris PF09026.10 KXS20813.1 - 0.011 16.1 0.5 0.011 16.1 0.5 5.5 5 1 0 5 5 5 0 Centromere protein B dimerisation domain Zip PF02535.22 KXS20813.1 - 0.29 10.3 0.8 0.58 9.3 0.8 1.5 1 1 0 1 1 1 0 ZIP Zinc transporter LRR_4 PF12799.7 KXS20816.1 - 0.0037 17.6 3.4 1.5 9.3 0.1 3.3 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXS20816.1 - 0.025 14.3 3.0 0.051 13.4 0.1 2.6 2 1 1 3 3 3 0 Leucine rich repeat GRA6 PF05084.13 KXS20816.1 - 0.25 11.3 0.0 0.36 10.8 0.0 1.2 1 0 0 1 1 1 0 Granule antigen protein (GRA6) MFS_1 PF07690.16 KXS20817.1 - 4.1e-54 183.8 48.5 2.2e-53 181.4 48.8 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KXS20817.1 - 5.3e-22 78.0 24.6 7e-22 77.6 24.6 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KXS20817.1 - 4e-12 45.7 33.6 8.9e-12 44.6 9.9 2.9 2 1 1 3 3 3 2 Sugar (and other) transporter LacY_symp PF01306.19 KXS20817.1 - 8.7e-05 21.5 10.7 0.0023 16.8 7.1 2.5 2 0 0 2 2 2 2 LacY proton/sugar symporter tRNA-synt_2b PF00587.25 KXS20818.1 - 2.1e-39 135.3 0.0 3.5e-39 134.6 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KXS20818.1 - 9.6e-15 54.5 0.2 1.9e-14 53.6 0.2 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.14 KXS20818.1 - 2.4e-05 24.3 0.1 4.7e-05 23.4 0.1 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain Ras PF00071.22 KXS20819.1 - 2e-58 196.5 0.0 2.7e-58 196.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXS20819.1 - 3.6e-37 127.2 0.1 5.3e-37 126.7 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXS20819.1 - 1.3e-14 54.0 0.0 1.6e-14 53.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KXS20819.1 - 1.9e-06 27.5 0.0 1.3e-05 24.8 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 KXS20819.1 - 8.1e-06 25.4 0.0 1.2e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KXS20819.1 - 4.2e-05 23.6 0.0 5.9e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KXS20819.1 - 0.00013 21.4 0.0 0.00016 21.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KXS20819.1 - 0.00015 21.7 0.0 0.18 11.7 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase FlgH PF02107.16 KXS20819.1 - 0.072 12.7 0.2 0.11 12.2 0.2 1.3 1 0 0 1 1 1 0 Flagellar L-ring protein TetR_C_16 PF17920.1 KXS20819.1 - 0.08 13.2 0.1 0.24 11.6 0.0 1.8 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain AAA_7 PF12775.7 KXS20819.1 - 0.13 11.7 0.0 0.22 11.0 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region RRM_1 PF00076.22 KXS20820.1 - 1.2e-47 159.6 0.0 1.6e-17 63.0 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KXS20820.1 - 2e-08 34.0 0.0 0.00034 20.4 0.0 3.4 3 0 0 3 3 3 2 Occluded RNA-recognition motif Ntox27 PF15531.6 KXS20820.1 - 0.028 14.3 0.0 0.063 13.2 0.0 1.5 1 0 0 1 1 1 0 Bacterial toxin 27 RRM_7 PF16367.5 KXS20820.1 - 0.088 12.9 0.0 1.9 8.7 0.0 2.7 2 1 0 2 2 2 0 RNA recognition motif Actin PF00022.19 KXS20821.1 - 0.0022 16.7 0.0 0.0033 16.1 0.0 1.3 1 0 0 1 1 1 1 Actin LRR_8 PF13855.6 KXS20822.1 - 9.8e-16 57.3 6.8 3.2e-09 36.4 0.6 3.8 2 1 2 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 KXS20822.1 - 4.4e-13 49.2 12.3 5.2e-05 23.5 0.2 4.1 5 0 0 5 5 5 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KXS20822.1 - 0.0012 18.4 0.9 0.22 11.0 0.1 2.2 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 KXS20822.1 - 0.026 15.0 13.7 23 6.0 0.2 6.6 5 2 0 5 5 5 0 Leucine Rich Repeat DUF3825 PF12873.7 KXS20822.1 - 0.13 11.7 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3825) DEAD PF00270.29 KXS20823.1 - 3.5e-50 170.2 0.0 6.1e-50 169.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXS20823.1 - 4.1e-33 114.0 0.0 1.7e-32 112.0 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXS20823.1 - 0.0002 21.4 0.0 0.00043 20.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 KXS20823.1 - 0.15 10.8 0.2 0.74 8.5 0.0 2.2 3 0 0 3 3 3 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 HA2 PF04408.23 KXS20824.1 - 3.3e-22 78.8 0.0 5.2e-22 78.2 0.0 1.4 1 0 0 1 1 1 1 Helicase associated domain (HA2) PTPA PF03095.15 KXS20825.1 - 1.2e-105 353.3 0.0 1.4e-105 353.1 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein adh_short PF00106.25 KXS20826.1 - 1.1e-39 135.9 0.0 1.5e-39 135.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXS20826.1 - 8.7e-28 97.5 0.0 1.4e-27 96.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXS20826.1 - 6.8e-07 29.4 0.1 1.3e-05 25.2 0.1 2.3 1 1 0 1 1 1 1 KR domain RIB43A PF05914.12 KXS20827.1 - 5.9e-78 262.2 57.9 6.7e-78 262.1 57.9 1.0 1 0 0 1 1 1 1 RIB43A RPN2_C PF18004.1 KXS20828.1 - 6.3e-56 188.7 12.8 6.3e-56 188.7 12.8 1.9 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 KXS20828.1 - 4.1e-34 115.3 29.0 6.3e-08 32.7 0.0 9.5 10 0 0 10 10 10 6 Proteasome/cyclosome repeat HEAT_2 PF13646.6 KXS20828.1 - 4.2e-19 68.7 12.3 2.1e-15 56.9 0.1 4.9 4 1 0 4 4 4 2 HEAT repeats HEAT PF02985.22 KXS20828.1 - 3.2e-05 23.8 0.4 3.7 8.1 0.1 4.8 4 0 0 4 4 4 1 HEAT repeat HEAT_EZ PF13513.6 KXS20828.1 - 7.4e-05 23.2 5.2 0.062 13.8 0.2 5.4 3 1 2 5 5 5 2 HEAT-like repeat LEM PF03020.15 KXS20828.1 - 0.0078 15.8 0.0 0.023 14.3 0.0 1.7 1 0 0 1 1 1 1 LEM domain Adaptin_N PF01602.20 KXS20828.1 - 0.036 12.6 0.2 5.5 5.4 0.2 3.6 3 1 0 3 3 3 0 Adaptin N terminal region Cnd1 PF12717.7 KXS20828.1 - 0.057 13.5 0.1 11 6.0 0.0 2.8 2 1 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 HEAT_PBS PF03130.16 KXS20828.1 - 0.53 11.1 5.9 31 5.6 0.1 5.1 5 0 0 5 5 4 0 PBS lyase HEAT-like repeat AAR2 PF05282.11 KXS20828.1 - 4.3 6.6 6.7 7.1 5.9 0.2 2.4 2 0 0 2 2 2 0 AAR2 protein CDC45 PF02724.14 KXS20828.1 - 8.9 4.5 12.0 13 3.9 12.0 1.1 1 0 0 1 1 1 0 CDC45-like protein TRAP_alpha PF03896.16 KXS20828.1 - 9.5 5.3 7.7 18 4.4 7.7 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit FKBP_C PF00254.28 KXS20830.1 - 6.9e-34 116.0 0.0 4.4e-33 113.5 0.0 2.2 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase NPL PF17800.1 KXS20830.1 - 6.5e-23 81.3 0.0 6.5e-23 81.3 0.0 2.6 2 1 0 2 2 2 1 Nucleoplasmin-like domain YL1 PF05764.13 KXS20830.1 - 4.6e-05 23.7 22.2 8.5e-05 22.8 22.2 1.4 1 0 0 1 1 1 1 YL1 nuclear protein LAP1C PF05609.12 KXS20830.1 - 0.26 10.4 9.7 0.3 10.1 9.7 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) GREB1 PF15782.5 KXS20830.1 - 1.5 5.8 10.2 2 5.5 10.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Hamartin PF04388.12 KXS20830.1 - 2.5 6.6 8.1 3.2 6.3 8.1 1.1 1 0 0 1 1 1 0 Hamartin protein DUF4661 PF15576.6 KXS20830.1 - 6.2 6.7 10.0 11 5.9 10.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) DUF572 PF04502.13 KXS20830.1 - 7.4 6.1 19.6 10 5.7 19.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Ald_Xan_dh_C2 PF02738.18 KXS20831.1 - 2.8e-164 547.6 0.3 4.1e-164 547.1 0.3 1.2 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.21 KXS20831.1 - 4.6e-31 107.9 0.1 1.2e-30 106.5 0.1 1.7 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.22 KXS20831.1 - 1.4e-27 96.2 0.1 3.3e-27 95.0 0.1 1.7 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.20 KXS20831.1 - 9.6e-26 89.6 0.7 2.7e-25 88.2 0.7 1.8 1 0 0 1 1 1 1 [2Fe-2S] binding domain CO_deh_flav_C PF03450.17 KXS20831.1 - 3e-13 49.8 0.0 1.7e-12 47.4 0.0 2.3 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Fer2 PF00111.27 KXS20831.1 - 0.00018 21.4 4.5 0.00025 20.9 0.2 2.6 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Sensor PF13796.6 KXS20832.1 - 0.17 11.9 0.2 0.36 10.9 0.2 1.4 1 0 0 1 1 1 0 Putative sensor ubiquitin PF00240.23 KXS20834.1 - 2.8e-13 49.4 0.2 2.8e-07 30.2 0.1 3.1 3 0 0 3 3 3 3 Ubiquitin family Rad60-SLD PF11976.8 KXS20834.1 - 0.00066 19.5 0.0 0.21 11.4 0.1 2.9 3 0 0 3 3 3 2 Ubiquitin-2 like Rad60 SUMO-like PIP5K PF01504.18 KXS20835.1 - 3.2e-43 147.9 0.0 6.8e-35 120.6 0.0 2.4 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 KXS20835.1 - 2.2e-27 95.9 0.0 3.5e-27 95.2 0.0 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.21 KXS20835.1 - 6.3e-19 67.9 8.0 6.3e-19 67.9 8.0 1.7 2 0 0 2 2 2 1 FYVE zinc finger FYVE_2 PF02318.16 KXS20835.1 - 0.04 14.1 3.6 0.11 12.7 3.6 1.7 1 0 0 1 1 1 0 FYVE-type zinc finger ACCA PF03255.14 KXS20835.1 - 0.041 13.8 0.1 0.098 12.5 0.1 1.6 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DZR PF12773.7 KXS20835.1 - 1.9 8.6 7.1 15 5.7 7.1 2.4 1 1 0 1 1 1 0 Double zinc ribbon IBR PF01485.21 KXS20835.1 - 2 8.7 9.4 6.8 7.0 4.4 2.8 3 0 0 3 3 3 0 IBR domain, a half RING-finger domain MyTH4 PF00784.17 KXS20836.1 - 2.7e-19 69.7 0.0 4.9e-19 68.8 0.0 1.5 1 0 0 1 1 1 1 MyTH4 domain FERM_M PF00373.18 KXS20836.1 - 3.8e-12 46.7 0.0 8.3e-12 45.6 0.0 1.6 1 0 0 1 1 1 1 FERM central domain FERM_C PF09380.10 KXS20836.1 - 0.073 13.5 0.0 0.4 11.1 0.0 2.1 2 0 0 2 2 2 0 FERM C-terminal PH-like domain FERM_N PF09379.10 KXS20836.1 - 0.17 11.9 0.0 0.39 10.7 0.0 1.6 1 0 0 1 1 1 0 FERM N-terminal domain Myosin_head PF00063.21 KXS20837.1 - 1.4e-233 777.0 0.3 1.6e-233 776.8 0.3 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) Hpr_kinase_C PF07475.12 KXS20837.1 - 0.0032 17.0 0.2 0.3 10.6 0.0 2.3 2 0 0 2 2 2 1 HPr Serine kinase C-terminal domain AAA_16 PF13191.6 KXS20837.1 - 0.0034 17.8 0.0 0.0076 16.6 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.22 KXS20837.1 - 0.013 15.8 0.1 0.033 14.6 0.1 1.7 1 0 0 1 1 1 0 RNA helicase AAA_10 PF12846.7 KXS20837.1 - 0.038 12.9 0.0 0.07 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain AAA_22 PF13401.6 KXS20837.1 - 0.13 12.5 0.0 0.31 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain IQ PF00612.27 KXS20838.1 - 5.6e-14 50.5 8.0 0.00033 20.2 0.1 3.8 3 0 0 3 3 3 3 IQ calmodulin-binding motif TPR_MLP1_2 PF07926.12 KXS20838.1 - 0.85 9.7 7.8 2.7 8.1 4.9 2.4 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein HMMR_N PF15905.5 KXS20838.1 - 2.3 7.6 5.6 0.22 11.0 0.5 1.8 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Fe-S_biosyn PF01521.20 KXS20839.1 - 3.7e-12 46.4 0.0 4e-12 46.3 0.0 1.0 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis F-box-like PF12937.7 KXS20842.1 - 4.2e-05 23.4 1.3 4.2e-05 23.4 1.3 3.0 2 0 0 2 2 2 1 F-box-like Abhydrolase_3 PF07859.13 KXS20843.1 - 2.2e-45 155.1 0.1 2.9e-45 154.7 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KXS20843.1 - 5.8e-06 25.4 0.5 3.4e-05 22.9 0.0 1.9 2 0 0 2 2 2 1 Carboxylesterase family Peptidase_S9 PF00326.21 KXS20843.1 - 2.5e-05 23.8 0.0 0.017 14.6 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 KXS20843.1 - 3.4e-05 24.6 7.4 5.4e-05 23.9 7.4 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.9 KXS20843.1 - 0.021 14.4 0.1 0.041 13.4 0.1 1.4 1 0 0 1 1 1 0 Esterase PHB depolymerase DLH PF01738.18 KXS20843.1 - 0.076 12.5 0.1 6.1 6.3 0.0 2.4 2 1 1 3 3 3 0 Dienelactone hydrolase family AXE1 PF05448.12 KXS20843.1 - 0.13 10.9 0.2 0.24 10.0 0.1 1.4 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Spermine_synth PF01564.17 KXS20845.1 - 2e-69 232.8 0.0 5.5e-69 231.4 0.0 1.7 2 0 0 2 2 2 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 KXS20845.1 - 1.5e-20 72.8 0.0 2.5e-20 72.1 0.0 1.4 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 KXS20845.1 - 0.00051 20.7 0.0 0.0012 19.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_30 PF05430.11 KXS20845.1 - 0.037 13.9 0.0 0.089 12.7 0.0 1.6 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase DRE2_N PF16803.5 KXS20845.1 - 0.086 13.1 0.0 0.29 11.4 0.0 1.9 1 1 0 1 1 1 0 Fe-S cluster assembly protein DRE2 N-terminus TIM PF00121.18 KXS20846.1 - 2.4e-93 312.0 0.2 2.8e-93 311.8 0.2 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase BRO1 PF03097.18 KXS20847.1 - 2.8e-96 322.7 0.1 2.4e-95 319.6 0.0 2.0 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 KXS20847.1 - 7.7e-70 235.5 5.0 1.4e-69 234.6 5.0 1.5 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV KBP_C PF12309.8 KXS20847.1 - 0.028 13.9 1.0 0.11 12.0 0.0 2.1 2 0 0 2 2 2 0 KIF-1 binding protein C terminal Sec34 PF04136.15 KXS20847.1 - 0.45 10.4 9.5 0.17 11.8 3.9 2.7 3 0 0 3 3 3 0 Sec34-like family ATP-synt_D PF01813.17 KXS20848.1 - 2.2e-72 243.0 0.9 2.7e-72 242.7 0.9 1.1 1 0 0 1 1 1 1 ATP synthase subunit D Motile_Sperm PF00635.26 KXS20849.1 - 8.4e-27 93.2 0.1 1.5e-26 92.4 0.1 1.4 1 0 0 1 1 1 1 MSP (Major sperm protein) domain ASH PF15780.5 KXS20849.1 - 0.0001 22.5 0.1 0.00021 21.4 0.1 1.5 1 0 0 1 1 1 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin DUF5001 PF16392.5 KXS20849.1 - 0.047 13.6 0.0 0.091 12.7 0.0 1.4 1 0 0 1 1 1 0 Ig-like domain LON_substr_bdg PF02190.16 KXS20851.1 - 1.8e-21 77.0 0.0 2.3e-21 76.6 0.0 1.2 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain zf-C3HC4_3 PF13920.6 KXS20851.1 - 9.6e-12 44.6 9.8 3.6e-09 36.3 3.8 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXS20851.1 - 1.3e-11 44.2 14.3 1.3e-11 44.1 7.4 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXS20851.1 - 6.8e-11 42.0 16.6 1.1e-08 34.9 9.1 3.0 2 0 0 2 2 2 2 RING-type zinc-finger zf-C3HC4 PF00097.25 KXS20851.1 - 1.2e-10 41.1 11.1 2.9e-08 33.4 6.7 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KXS20851.1 - 6.2e-10 39.1 17.7 2.6e-08 33.9 9.4 2.6 2 0 0 2 2 2 2 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 KXS20851.1 - 9e-09 35.2 10.0 1.8e-06 27.8 5.7 2.6 2 0 0 2 2 2 2 zinc-RING finger domain zf-RING_2 PF13639.6 KXS20851.1 - 4e-07 30.3 15.3 8.2e-07 29.3 7.1 3.1 3 0 0 3 3 3 1 Ring finger domain zf-RING_4 PF14570.6 KXS20851.1 - 3.2e-05 23.6 6.2 0.0058 16.4 4.4 3.1 2 1 0 2 2 2 1 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 KXS20851.1 - 4.8e-05 23.1 15.4 0.00012 21.9 6.9 2.8 2 1 0 2 2 2 1 Prokaryotic RING finger family 4 U-box PF04564.15 KXS20851.1 - 0.00035 20.7 0.0 0.001 19.2 0.0 1.8 1 0 0 1 1 1 1 U-box domain zf-RING_10 PF16685.5 KXS20851.1 - 0.00065 19.8 3.1 0.00065 19.8 3.1 2.4 2 0 0 2 2 2 1 zinc RING finger of MSL2 zf-Nse PF11789.8 KXS20851.1 - 0.0082 15.9 6.4 0.052 13.4 2.8 2.6 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit DBD_Tnp_Mut PF03108.15 KXS20851.1 - 0.099 12.6 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 MuDR family transposase Rad50_zn_hook PF04423.14 KXS20851.1 - 0.67 9.8 2.1 6.7 6.6 0.1 2.4 2 0 0 2 2 2 0 Rad50 zinc hook motif Nop PF01798.18 KXS20852.1 - 2.9e-70 236.3 0.0 4.7e-70 235.6 0.0 1.3 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 KXS20852.1 - 2.8e-35 121.8 1.9 2.8e-35 121.8 1.9 1.8 2 0 0 2 2 2 1 Prp31 C terminal domain Topo_Zn_Ribbon PF08272.11 KXS20852.1 - 0.16 11.7 0.3 0.33 10.6 0.3 1.4 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like Acyltransferase PF01553.21 KXS20853.1 - 5.7e-15 55.1 0.0 1e-14 54.3 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase DUF1752 PF08550.10 KXS20853.1 - 3.3e-05 23.6 3.8 0.029 14.2 0.3 2.5 2 0 0 2 2 2 2 Fungal protein of unknown function (DUF1752) Tetraspanin PF00335.20 KXS20854.1 - 1.2e-11 44.7 22.2 1.6e-10 41.1 13.9 2.1 1 1 1 2 2 2 2 Tetraspanin family Pkinase PF00069.25 KXS20855.1 - 5.3e-61 206.3 0.0 5.3e-61 206.3 0.0 2.5 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS20855.1 - 6.4e-33 114.1 0.2 1.6e-32 112.8 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase C1_1 PF00130.22 KXS20855.1 - 3.5e-14 52.4 20.2 6.8e-08 32.3 6.7 2.4 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.24 KXS20855.1 - 1.3e-09 38.6 1.4 5.1e-09 36.7 1.4 2.1 1 0 0 1 1 1 1 Protein kinase C terminal domain HR1 PF02185.16 KXS20855.1 - 4.7e-08 33.0 9.5 4.4e-06 26.7 5.3 5.6 3 1 2 5 5 4 2 Hr1 repeat C1_2 PF03107.16 KXS20855.1 - 0.0027 18.0 19.6 0.0047 17.2 7.5 2.4 2 0 0 2 2 2 2 C1 domain C2 PF00168.30 KXS20855.1 - 0.052 13.8 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 C2 domain V_ATPase_I PF01496.19 KXS20855.1 - 0.87 7.4 9.2 1.4 6.7 9.2 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family zf-RING-like PF08746.11 KXS20855.1 - 2.5 8.5 18.8 0.34 11.2 8.9 2.6 2 0 0 2 2 2 0 RING-like domain OrfB_Zn_ribbon PF07282.11 KXS20855.1 - 4.9 7.1 17.4 8.7 6.4 4.5 2.7 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Pkinase_fungal PF17667.1 KXS20855.1 - 6.7 5.4 10.2 53 2.4 0.0 2.2 2 0 0 2 2 2 0 Fungal protein kinase Hydrolase_4 PF12146.8 KXS20856.1 - 8e-06 25.3 0.0 0.024 13.9 0.0 3.0 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KXS20856.1 - 0.00014 21.6 0.2 0.34 10.5 0.0 2.9 2 1 1 3 3 3 2 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 KXS20856.1 - 0.18 11.4 0.0 0.35 10.4 0.0 1.4 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) 5-FTHF_cyc-lig PF01812.20 KXS20857.1 - 1.9e-45 155.0 0.0 2.5e-45 154.6 0.0 1.1 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family LRAT PF04970.13 KXS20858.1 - 4.1e-11 43.3 0.6 1.4e-10 41.6 0.6 1.8 1 1 0 1 1 1 1 Lecithin retinol acyltransferase Romo1 PF10247.9 KXS20858.1 - 0.091 13.1 0.2 0.22 11.9 0.2 1.6 1 0 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 DUF3079 PF11278.8 KXS20858.1 - 0.15 11.9 2.7 0.42 10.4 2.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3079) UPF0016 PF01169.19 KXS20859.1 - 1.5e-41 140.6 20.1 1.7e-21 76.3 4.9 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 Mntp PF02659.15 KXS20859.1 - 0.0013 18.5 4.8 0.0074 16.1 0.0 2.2 2 0 0 2 2 2 1 Putative manganese efflux pump DUF697 PF05128.12 KXS20859.1 - 0.03 14.0 3.8 0.047 13.4 0.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF697) PDR_assoc PF08370.11 KXS20859.1 - 0.041 13.6 0.2 9.9 6.0 0.1 2.5 2 0 0 2 2 2 0 Plant PDR ABC transporter associated DUF308 PF03729.13 KXS20859.1 - 0.13 12.6 7.5 0.72 10.2 0.1 3.0 2 1 0 2 2 2 0 Short repeat of unknown function (DUF308) DUF3995 PF13160.6 KXS20859.1 - 1.6 9.1 11.3 0.58 10.5 2.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3995) HEAT_EZ PF13513.6 KXS20860.1 - 7e-18 64.7 18.7 6.2e-14 52.1 0.1 8.1 7 3 3 10 10 10 3 HEAT-like repeat HEAT PF02985.22 KXS20860.1 - 9e-15 53.5 21.1 7.5e-05 22.7 0.0 10.1 12 0 0 12 12 10 2 HEAT repeat IBN_N PF03810.19 KXS20860.1 - 5.2e-10 39.1 1.1 2.3e-08 33.8 0.2 3.0 2 0 0 2 2 2 1 Importin-beta N-terminal domain HEAT_2 PF13646.6 KXS20860.1 - 6.4e-07 29.7 0.3 0.0011 19.3 0.0 6.4 3 2 6 9 9 9 3 HEAT repeats IFRD PF05004.13 KXS20860.1 - 1.4e-06 27.7 3.1 0.36 9.9 0.0 4.7 4 1 0 5 5 5 2 Interferon-related developmental regulator (IFRD) Arm PF00514.23 KXS20860.1 - 2.4e-05 24.2 9.9 0.0042 17.1 0.1 5.9 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat CLASP_N PF12348.8 KXS20860.1 - 2.9e-05 23.7 0.4 0.07 12.7 0.0 3.8 4 0 0 4 4 4 2 CLASP N terminal TIP120 PF08623.10 KXS20860.1 - 4.6e-05 23.3 2.5 1.4 8.7 0.1 3.8 2 1 0 3 3 3 2 TATA-binding protein interacting (TIP20) DRIM PF07539.12 KXS20860.1 - 0.00088 17.7 1.9 0.07 11.4 0.0 3.6 3 1 0 3 3 3 1 Down-regulated in metastasis RIX1 PF08167.12 KXS20860.1 - 0.0022 17.8 5.3 3.8 7.2 0.0 5.6 7 1 0 7 7 7 1 rRNA processing/ribosome biogenesis MMS19_C PF12460.8 KXS20860.1 - 0.0024 17.1 3.4 0.76 8.8 0.9 3.5 2 1 1 3 3 3 2 RNAPII transcription regulator C-terminal Cnd1 PF12717.7 KXS20860.1 - 0.017 15.2 2.7 0.1 12.6 0.0 3.4 3 2 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Dicer_dimer PF03368.14 KXS20861.1 - 0.00092 19.3 0.0 0.0021 18.1 0.0 1.6 1 0 0 1 1 1 1 Dicer dimerisation domain dsrm PF00035.26 KXS20861.1 - 0.0086 16.8 0.0 0.019 15.7 0.0 1.6 1 0 0 1 1 1 1 Double-stranded RNA binding motif Spectrin PF00435.21 KXS20861.1 - 0.013 16.0 1.7 0.027 15.0 1.4 1.7 1 1 0 1 1 1 0 Spectrin repeat DivIC PF04977.15 KXS20861.1 - 0.27 11.0 1.9 22 4.9 0.0 2.7 2 0 0 2 2 2 0 Septum formation initiator SWI-SNF_Ssr4 PF08549.10 KXS20862.1 - 5.9e-17 61.6 5.8 3.8e-08 32.5 0.5 2.9 3 0 0 3 3 3 3 Fungal domain of unknown function (DUF1750) PP-binding_2 PF14573.6 KXS20862.1 - 0.088 13.1 0.1 0.17 12.1 0.1 1.5 1 0 0 1 1 1 0 Acyl-carrier ATP-synt_C PF00137.21 KXS20863.1 - 1.1e-33 115.3 36.2 5.5e-22 77.9 15.0 2.2 2 0 0 2 2 2 2 ATP synthase subunit C Nas2_N PF18265.1 KXS20864.1 - 1.1e-26 92.5 0.1 1.8e-26 91.8 0.1 1.3 1 0 0 1 1 1 1 Nas2 N_terminal domain PDZ_6 PF17820.1 KXS20864.1 - 3.5e-06 26.8 0.0 7e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.14 KXS20864.1 - 0.0002 21.7 0.0 0.00026 21.3 0.0 1.2 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain PDZ_2 PF13180.6 KXS20864.1 - 0.00059 20.1 0.0 0.0012 19.1 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KXS20864.1 - 0.0057 17.0 0.0 0.0094 16.3 0.0 1.5 1 0 0 1 1 1 1 PDZ domain Mito_carr PF00153.27 KXS20865.1 - 2.4e-64 213.3 1.7 1.4e-22 79.4 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein CNDH2_C PF16858.5 KXS20866.1 - 1.4e-46 159.7 0.0 5.1e-46 157.9 0.0 1.9 2 0 0 2 2 2 1 Condensin II complex subunit CAP-H2 or CNDH2, C-term CNDH2_N PF06278.11 KXS20866.1 - 2.1e-19 69.8 0.2 5.1e-19 68.5 0.2 1.6 1 0 0 1 1 1 1 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal CNDH2_M PF16869.5 KXS20866.1 - 0.069 13.8 0.0 0.069 13.8 0.0 4.4 3 1 0 3 3 3 0 PF16858 T2SSF PF00482.23 KXS20866.1 - 0.1 12.5 0.1 21 5.1 0.0 2.7 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein F DDE_Tnp_4 PF13359.6 KXS20868.1 - 7.4e-11 42.0 0.0 8.4e-11 41.8 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease RNA_bind PF08675.11 KXS20870.1 - 9.8e-10 38.3 0.1 5.4e-09 36.0 0.2 1.9 2 0 0 2 2 2 1 RNA binding domain NCBP3 PF10309.9 KXS20870.1 - 1.6e-05 24.6 0.8 2.8e-05 23.9 0.8 1.3 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 GARP PF16731.5 KXS20871.1 - 0.16 11.6 2.4 0.25 11.0 2.4 1.2 1 0 0 1 1 1 0 Glutamic acid/alanine-rich protein of Trypanosoma Actin PF00022.19 KXS20872.1 - 2.3e-143 477.7 0.0 2.7e-143 477.5 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.13 KXS20872.1 - 1.9e-05 23.6 0.0 0.006 15.4 0.0 2.3 2 0 0 2 2 2 2 MreB/Mbl protein DUF3769 PF12600.8 KXS20872.1 - 0.13 11.2 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3769) Adap_comp_sub PF00928.21 KXS20873.1 - 5.7e-26 91.5 0.0 9.7e-26 90.7 0.0 1.3 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KXS20873.1 - 2e-06 27.8 0.0 3.1e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain RPM2 PF08579.11 KXS20873.1 - 0.027 14.8 0.2 0.05 14.0 0.2 1.4 1 0 0 1 1 1 0 Mitochondrial ribonuclease P subunit (RPM2) DUF4337 PF14235.6 KXS20873.1 - 0.11 12.6 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) AP-5_subunit_s1 PF15001.6 KXS20873.1 - 0.13 12.3 0.1 0.13 12.3 0.1 2.0 2 0 0 2 2 2 0 AP-5 complex subunit sigma-1 muHD PF10291.9 KXS20873.1 - 0.13 11.7 0.0 0.32 10.4 0.0 1.6 1 1 0 1 1 1 0 Muniscin C-terminal mu homology domain P21-Arc PF04062.14 KXS20874.1 - 4.2e-69 232.1 0.0 4.9e-69 231.8 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit ITAM_Cys-rich PF10538.9 KXS20874.1 - 0.64 9.8 3.8 6.5 6.6 0.3 2.5 2 0 0 2 2 2 0 Immunoreceptor tyrosine-based activation motif BSD PF03909.17 KXS20877.1 - 8.7e-16 57.7 0.2 1.7e-15 56.7 0.2 1.4 1 0 0 1 1 1 1 BSD domain KH_6 PF15985.5 KXS20878.1 - 9.6e-14 51.5 0.1 2.8e-13 50.0 0.1 1.8 2 0 0 2 2 2 1 KH domain ECR1_N PF14382.6 KXS20878.1 - 6.3e-12 45.1 0.0 1.1e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region EXOSC1 PF10447.9 KXS20878.1 - 0.0082 16.7 0.5 0.19 12.3 0.2 2.4 1 1 1 2 2 2 1 Exosome component EXOSC1/CSL4 Pyr_redox_2 PF07992.14 KXS20879.1 - 4.6e-41 141.0 0.0 5.9e-41 140.6 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AIF_C PF14721.6 KXS20879.1 - 9e-34 116.6 0.6 7.7e-18 65.1 0.0 2.4 1 1 1 2 2 2 2 Apoptosis-inducing factor, mitochondrion-associated, C-term Pyr_redox PF00070.27 KXS20879.1 - 9e-11 42.2 0.0 1.9e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXS20879.1 - 6e-07 29.0 0.0 8.3e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXS20879.1 - 0.00049 19.8 0.9 0.0033 17.0 0.7 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 KXS20879.1 - 0.0018 17.6 0.0 0.0027 17.0 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 KXS20879.1 - 0.0022 18.0 0.2 0.053 13.5 0.1 3.0 3 1 1 4 4 4 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 KXS20879.1 - 0.0077 15.4 0.0 0.025 13.7 0.0 1.7 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Reductase_C PF14759.6 KXS20879.1 - 0.04 14.5 0.0 0.1 13.2 0.0 1.7 1 0 0 1 1 1 0 Reductase C-terminal HI0933_like PF03486.14 KXS20879.1 - 0.13 11.0 0.0 0.31 9.7 0.0 1.6 2 0 0 2 2 2 0 HI0933-like protein SAICAR_synt PF01259.18 KXS20880.1 - 2.6e-102 341.7 0.0 3.3e-102 341.4 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase Orn_Arg_deC_N PF02784.16 KXS20881.1 - 1.7e-81 273.2 0.0 2.3e-81 272.8 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 KXS20881.1 - 1.2e-20 73.6 0.0 1.5e-20 73.2 0.0 1.4 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Ank PF00023.30 KXS20882.1 - 3.6e-22 77.8 4.0 3.8e-05 24.0 0.4 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_2 PF12796.7 KXS20882.1 - 2e-20 73.1 0.2 8.5e-12 45.5 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXS20882.1 - 1.5e-16 58.8 3.5 0.00039 20.6 0.0 3.9 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 KXS20882.1 - 3.9e-15 55.7 3.7 9.8e-06 25.8 0.0 3.9 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXS20882.1 - 1.6e-14 54.0 3.2 2.7e-07 31.0 0.9 3.0 1 1 3 4 4 4 3 Ankyrin repeats (many copies) IF-2B PF01008.17 KXS20883.1 - 4.5e-70 236.1 0.8 5.7e-70 235.7 0.8 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family DUF2508 PF10704.9 KXS20883.1 - 0.17 12.1 0.1 0.49 10.6 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2508) CAF1 PF04857.20 KXS20884.1 - 1.3e-22 80.4 0.1 1.1e-10 41.2 0.0 2.4 2 1 0 2 2 2 2 CAF1 family ribonuclease GARS_A PF01071.19 KXS20885.1 - 6e-81 270.9 0.0 8.8e-81 270.3 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.15 KXS20885.1 - 3.6e-34 117.4 0.0 2.2e-33 114.9 0.0 2.4 3 0 0 3 3 3 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.22 KXS20885.1 - 2.9e-31 108.7 0.0 6.3e-31 107.6 0.0 1.6 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.16 KXS20885.1 - 2.7e-29 101.3 0.3 8.2e-29 99.7 0.3 1.9 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.24 KXS20885.1 - 3e-15 56.6 2.4 8.7e-14 52.0 1.9 3.2 3 0 0 3 3 3 1 AIR synthase related protein, N-terminal domain ATP-grasp_3 PF02655.14 KXS20885.1 - 0.0015 18.6 0.0 0.0038 17.3 0.0 1.8 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.22 KXS20885.1 - 0.018 14.6 0.0 0.033 13.7 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain ATP-grasp_4 PF13535.6 KXS20885.1 - 0.031 13.9 0.1 0.061 12.9 0.1 1.4 1 0 0 1 1 1 0 ATP-grasp domain Gpi1 PF05024.15 KXS20886.1 - 1.1e-52 178.9 8.4 1.8e-52 178.1 8.4 1.4 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) Kinetochor_Ybp2 PF08568.10 KXS20887.1 - 0.01 14.4 0.0 0.013 14.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family, YAP/Alf4/glomulin Complex1_49kDa PF00346.19 KXS20888.1 - 0.0058 15.8 0.0 0.0088 15.2 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit Pet127 PF08634.10 KXS20889.1 - 2.5e-87 292.8 0.0 3.4e-87 292.4 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial protein Pet127 ABC_tran PF00005.27 KXS20890.1 - 6.4e-48 162.7 0.0 2.2e-25 89.7 0.0 4.3 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KXS20890.1 - 1e-15 58.3 0.0 0.0018 18.1 0.0 4.3 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KXS20890.1 - 6.3e-13 48.7 0.5 0.051 13.0 0.0 4.5 4 1 0 5 5 4 4 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KXS20890.1 - 6.3e-09 35.5 0.1 0.0027 17.4 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_28 PF13521.6 KXS20890.1 - 1.3e-06 28.7 0.0 0.037 14.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 KXS20890.1 - 8.9e-06 25.8 0.0 0.043 13.9 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.6 KXS20890.1 - 1.2e-05 25.9 11.3 0.011 16.2 0.0 3.9 4 1 0 4 4 3 2 AAA domain AAA_18 PF13238.6 KXS20890.1 - 2.2e-05 25.0 0.0 0.25 11.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KXS20890.1 - 2.3e-05 24.2 1.0 0.67 9.7 0.0 3.7 3 1 0 3 3 3 2 AAA domain AAA_16 PF13191.6 KXS20890.1 - 3.2e-05 24.4 0.1 0.11 12.9 0.0 3.2 2 1 0 2 2 2 1 AAA ATPase domain Adaptin_N PF01602.20 KXS20890.1 - 3.6e-05 22.5 2.1 0.029 12.9 0.2 2.2 1 1 1 2 2 2 2 Adaptin N terminal region CLASP_N PF12348.8 KXS20890.1 - 7.5e-05 22.4 1.6 0.06 12.9 0.2 3.1 3 0 0 3 3 3 1 CLASP N terminal RsgA_GTPase PF03193.16 KXS20890.1 - 0.00011 22.2 0.0 0.095 12.6 0.0 2.6 2 0 0 2 2 2 1 RsgA GTPase MeaB PF03308.16 KXS20890.1 - 0.00011 21.3 0.9 0.039 12.9 0.0 2.9 3 0 0 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_33 PF13671.6 KXS20890.1 - 0.00014 22.1 0.1 0.12 12.6 0.0 3.1 3 0 0 3 3 2 1 AAA domain Chromo PF00385.24 KXS20890.1 - 0.00015 21.6 0.3 0.00035 20.4 0.3 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA PF00004.29 KXS20890.1 - 0.00022 21.6 0.0 3.3 8.2 0.0 3.8 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KXS20890.1 - 0.00029 21.1 0.2 1.6 9.0 0.0 3.3 3 0 0 3 3 2 1 AAA domain NACHT PF05729.12 KXS20890.1 - 0.00039 20.4 0.0 0.26 11.2 0.0 2.7 2 0 0 2 2 2 1 NACHT domain AAA_15 PF13175.6 KXS20890.1 - 0.00076 19.3 0.0 0.91 9.2 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain RNA_helicase PF00910.22 KXS20890.1 - 0.0016 18.8 0.0 2 8.8 0.0 2.8 2 0 0 2 2 2 1 RNA helicase 4HB PF17947.1 KXS20890.1 - 0.0023 18.0 0.0 0.0084 16.2 0.0 2.0 1 0 0 1 1 1 1 Four helical bundle domain NTPase_1 PF03266.15 KXS20890.1 - 0.0024 17.8 0.1 2.6 7.9 0.0 2.9 2 0 0 2 2 2 1 NTPase AAA_14 PF13173.6 KXS20890.1 - 0.0046 17.0 0.0 0.91 9.6 0.0 2.9 2 0 0 2 2 2 1 AAA domain HEAT_EZ PF13513.6 KXS20890.1 - 0.0054 17.2 2.3 18 6.0 0.0 5.1 3 1 2 5 5 5 0 HEAT-like repeat cobW PF02492.19 KXS20890.1 - 0.0061 16.2 0.0 3.6 7.2 0.0 2.8 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain ATP-synt_ab PF00006.25 KXS20890.1 - 0.0074 16.0 0.1 1.9 8.1 0.0 2.7 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_24 PF13479.6 KXS20890.1 - 0.0098 15.6 0.0 1.2 8.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 KXS20890.1 - 0.0099 16.0 1.2 3.1 7.8 0.0 3.0 3 0 0 3 3 2 1 Helicase HerA, central domain CLP1_P PF16575.5 KXS20890.1 - 0.012 15.5 0.0 8.4 6.1 0.0 3.6 3 0 0 3 3 3 0 mRNA cleavage and polyadenylation factor CLP1 P-loop DUF815 PF05673.13 KXS20890.1 - 0.013 14.7 0.0 3.1 6.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_27 PF13514.6 KXS20890.1 - 0.014 15.0 0.0 5.7 6.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_13 PF13166.6 KXS20890.1 - 0.015 14.0 0.0 1.5 7.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain ParcG PF10274.9 KXS20890.1 - 0.016 15.3 3.2 7.8 6.6 0.1 3.3 2 1 1 3 3 3 0 Parkin co-regulated protein AAA_25 PF13481.6 KXS20890.1 - 0.022 14.3 0.0 9.6 5.7 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KXS20890.1 - 0.023 14.2 0.0 6.7 6.2 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region Dynamin_N PF00350.23 KXS20890.1 - 0.025 14.6 0.1 0.58 10.2 0.0 2.7 2 0 0 2 2 2 0 Dynamin family NB-ARC PF00931.22 KXS20890.1 - 0.037 13.2 0.4 5 6.2 0.0 2.7 3 0 0 3 3 2 0 NB-ARC domain TsaE PF02367.17 KXS20890.1 - 0.037 14.0 0.6 15 5.6 0.1 2.9 3 0 0 3 3 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 KXS20890.1 - 0.043 13.1 0.2 14 4.9 0.0 3.2 3 0 0 3 3 3 0 Zeta toxin AAA_5 PF07728.14 KXS20890.1 - 0.054 13.5 0.1 9.3 6.3 0.0 3.4 4 0 0 4 4 2 0 AAA domain (dynein-related subfamily) MutS_V PF00488.21 KXS20890.1 - 0.059 13.4 0.1 5.8 6.9 0.0 2.4 2 0 0 2 2 2 0 MutS domain V MMS19_N PF14500.6 KXS20890.1 - 0.068 12.7 0.2 36 3.8 0.0 3.3 2 1 1 3 3 3 0 Dos2-interacting transcription regulator of RNA-Pol-II MukB PF04310.12 KXS20890.1 - 0.081 12.7 0.1 9.1 6.0 0.1 2.4 2 0 0 2 2 2 0 MukB N-terminal ATPase_2 PF01637.18 KXS20890.1 - 0.095 12.6 0.1 16 5.3 0.0 3.0 3 0 0 3 3 2 0 ATPase domain predominantly from Archaea ATP_bind_1 PF03029.17 KXS20890.1 - 0.096 12.5 1.0 11 5.8 0.0 3.0 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein HEAT PF02985.22 KXS20890.1 - 0.11 12.8 0.9 1.9 8.9 0.2 3.5 4 0 0 4 4 2 0 HEAT repeat Roc PF08477.13 KXS20890.1 - 0.11 12.7 0.0 21 5.4 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase UME PF08064.13 KXS20890.1 - 0.14 12.1 1.8 3.4 7.6 0.0 3.0 2 1 1 3 3 2 0 UME (NUC010) domain MMS19_C PF12460.8 KXS20890.1 - 0.41 9.7 8.7 2.8 6.9 0.5 3.5 2 1 2 4 4 4 0 RNAPII transcription regulator C-terminal GATase_6 PF13522.6 KXS20892.1 - 9.8e-15 54.9 0.0 2e-14 54.0 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 KXS20892.1 - 6.9e-13 48.6 0.0 1.3e-12 47.7 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 KXS20892.1 - 1.4e-07 31.2 0.0 2.4e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.6 KXS20892.1 - 0.00011 21.2 0.0 0.00017 20.6 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II ADK PF00406.22 KXS20893.1 - 2e-36 125.3 0.1 5.7e-36 123.9 0.1 1.6 1 1 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KXS20893.1 - 3.2e-27 95.6 1.6 2.6e-26 92.7 1.6 1.9 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KXS20893.1 - 5e-09 36.8 0.0 8.8e-09 36.0 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KXS20893.1 - 9.7e-05 22.6 0.0 0.00018 21.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain Ploopntkinase3 PF18751.1 KXS20893.1 - 0.011 15.7 0.0 0.023 14.6 0.0 1.5 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 Thymidylate_kin PF02223.17 KXS20893.1 - 0.033 13.9 0.0 0.054 13.2 0.0 1.4 1 1 0 1 1 1 0 Thymidylate kinase dNK PF01712.19 KXS20893.1 - 0.068 13.0 0.2 0.12 12.2 0.0 1.6 2 0 0 2 2 2 0 Deoxynucleoside kinase Como_LCP PF02247.16 KXS20893.1 - 0.11 11.1 0.0 0.17 10.5 0.0 1.2 1 0 0 1 1 1 0 Large coat protein NACHT PF05729.12 KXS20893.1 - 0.17 11.8 0.0 0.22 11.5 0.0 1.2 1 0 0 1 1 1 0 NACHT domain HAD PF12710.7 KXS20894.1 - 1.7e-07 31.8 0.0 1.2e-06 29.0 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Sigma70_r1_2 PF00140.20 KXS20894.1 - 0.025 14.6 0.0 0.044 13.8 0.0 1.4 1 0 0 1 1 1 0 Sigma-70 factor, region 1.2 Put_Phosphatase PF06888.12 KXS20894.1 - 0.13 11.7 0.0 3 7.2 0.0 2.1 2 0 0 2 2 2 0 Putative Phosphatase Rer1 PF03248.13 KXS20895.1 - 4.7e-79 264.1 1.8 5.5e-79 263.8 1.8 1.0 1 0 0 1 1 1 1 Rer1 family DUF2208 PF09973.9 KXS20895.1 - 0.16 11.6 4.5 0.3 10.7 4.5 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2208) DUF5408 PF17402.2 KXS20895.1 - 0.26 11.2 1.3 0.44 10.5 0.7 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5408) DUF1538 PF07556.11 KXS20895.1 - 0.45 9.8 4.0 0.48 9.7 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1538) Halogen_Hydrol PF10112.9 KXS20895.1 - 0.69 9.9 3.2 18 5.3 1.5 2.1 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Methyltransf_12 PF08242.12 KXS20896.1 - 2.6e-11 44.2 0.0 5.3e-11 43.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXS20896.1 - 1.2e-10 42.0 0.0 2.9e-10 40.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXS20896.1 - 1.6e-08 35.1 0.0 3.7e-08 33.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXS20896.1 - 4.5e-08 33.1 0.0 6.2e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXS20896.1 - 6.9e-05 22.7 0.0 0.00012 21.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXS20896.1 - 0.00025 20.6 0.0 0.00047 19.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 KXS20896.1 - 0.078 12.3 0.0 0.14 11.5 0.0 1.5 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Phage_hub_GP28 PF11110.8 KXS20896.1 - 0.15 11.9 0.2 2.5 8.0 0.0 2.2 2 0 0 2 2 2 0 Baseplate hub distal subunit Methyltransf_29 PF03141.16 KXS20896.1 - 0.18 10.4 0.0 0.23 10.0 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Peptidase_M14 PF00246.24 KXS20897.1 - 2.1e-75 254.2 0.0 2.4e-75 254.0 0.0 1.0 1 0 0 1 1 1 1 Zinc carboxypeptidase F-box-like PF12937.7 KXS20898.1 - 9.8e-06 25.4 0.7 2.4e-05 24.1 0.7 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXS20898.1 - 0.053 13.4 2.0 0.2 11.6 2.0 1.9 1 1 0 1 1 1 0 F-box domain Frataxin_Cyay PF01491.16 KXS20899.1 - 2.4e-39 133.8 0.0 2.6e-39 133.6 0.0 1.0 1 0 0 1 1 1 1 Frataxin-like domain Pkinase_Tyr PF07714.17 KXS20900.1 - 8.2e-49 166.2 0.0 1.3e-48 165.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXS20900.1 - 1.3e-43 149.3 0.0 1.9e-43 148.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain VIT PF08487.10 KXS20900.1 - 2.5e-32 111.4 0.0 4.1e-32 110.7 0.0 1.3 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.6 KXS20900.1 - 1.1e-15 57.9 0.0 1.7e-15 57.3 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT_2 PF13757.6 KXS20900.1 - 2.4e-12 46.6 0.0 1.7e-11 43.8 0.0 2.1 2 0 0 2 2 2 1 Vault protein inter-alpha-trypsin domain RNA_pol_Rpb1_R PF05001.13 KXS20900.1 - 9.2e-08 32.1 95.4 0.0039 17.5 12.2 6.6 3 1 5 9 9 9 7 RNA polymerase Rpb1 C-terminal repeat VWA_2 PF13519.6 KXS20900.1 - 5.6e-06 27.0 0.0 1.1e-05 26.1 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain Kinase-like PF14531.6 KXS20900.1 - 0.00029 20.3 0.0 0.00049 19.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KXS20900.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Dyp_perox PF04261.12 KXS20900.1 - 0.23 10.4 0.1 0.65 8.9 0.0 1.6 1 1 0 1 1 1 0 Dyp-type peroxidase family PLA2G12 PF06951.11 KXS20901.1 - 0.00031 20.7 1.3 0.00038 20.4 1.3 1.2 1 0 0 1 1 1 1 Group XII secretory phospholipase A2 precursor (PLA2G12) PLA2G12 PF06951.11 KXS20902.1 - 6.1e-14 52.3 16.7 2.1e-13 50.6 16.7 1.8 1 1 0 1 1 1 1 Group XII secretory phospholipase A2 precursor (PLA2G12) Phospholip_A2_3 PF09056.11 KXS20902.1 - 0.00053 20.6 8.8 0.0015 19.1 8.8 1.8 1 1 0 1 1 1 1 Prokaryotic phospholipase A2 UCH PF00443.29 KXS20905.1 - 1.1e-41 143.1 0.0 1.5e-41 142.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KXS20905.1 - 5.2e-16 59.1 0.1 1.5e-14 54.3 0.1 2.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Hepatitis_core PF00906.20 KXS20905.1 - 0.23 11.0 2.3 0.44 10.1 2.3 1.3 1 0 0 1 1 1 0 Hepatitis core antigen RPE65 PF03055.15 KXS20906.1 - 8.8e-65 219.7 0.0 1.1e-64 219.4 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Ldh_1_N PF00056.23 KXS20907.1 - 2e-46 157.6 0.3 3.2e-46 156.9 0.3 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 KXS20907.1 - 1.1e-43 149.1 0.0 1.6e-43 148.6 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.19 KXS20907.1 - 7.9e-05 21.8 0.0 0.00011 21.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_trans_1_4 PF13692.6 KXS20907.1 - 0.055 13.9 0.0 0.13 12.7 0.0 1.7 1 0 0 1 1 1 0 Glycosyl transferases group 1 Glyco_hydro_4 PF02056.16 KXS20907.1 - 0.16 11.5 0.3 3.7 7.1 0.0 2.4 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase WD40 PF00400.32 KXS20909.1 - 5.5e-38 128.3 16.3 1.3e-05 25.8 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXS20909.1 - 4e-15 55.9 0.0 0.024 14.9 0.1 5.1 1 1 4 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KXS20909.1 - 0.0001 22.3 0.0 0.067 13.1 0.0 2.4 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KXS20909.1 - 0.013 14.9 0.0 0.16 11.2 0.0 2.5 1 1 0 2 2 2 0 WD40-like domain Nup160 PF11715.8 KXS20909.1 - 0.03 13.0 0.2 1.3 7.6 0.0 2.3 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KXS20909.1 - 0.05 12.5 1.6 31 3.4 0.0 3.7 2 1 2 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein CAP_C PF08603.11 KXS20910.1 - 2e-05 24.3 0.3 0.00058 19.5 0.1 2.0 2 0 0 2 2 2 2 Adenylate cyclase associated (CAP) C terminal 2-Hacid_dh_C PF02826.19 KXS20911.1 - 1.5e-40 138.5 0.0 2.4e-40 137.8 0.0 1.3 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KXS20911.1 - 3.5e-21 75.3 0.0 3.9e-21 75.1 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KXS20911.1 - 2e-06 28.1 0.0 3.1e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase DUF4246 PF14033.6 KXS20912.1 - 2.8e-106 356.3 0.0 3.5e-106 356.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) GRAM PF02893.20 KXS20913.1 - 1.2e-06 28.4 0.0 1.4e-06 28.1 0.0 1.1 1 0 0 1 1 1 1 GRAM domain bPH_3 PF14470.6 KXS20913.1 - 0.017 15.5 0.0 0.021 15.2 0.0 1.2 1 0 0 1 1 1 0 Bacterial PH domain Vps36_ESCRT-II PF11605.8 KXS20913.1 - 0.019 15.2 0.0 0.027 14.6 0.0 1.2 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 Rod_C PF10493.9 KXS20915.1 - 9.3e-48 162.9 0.1 1.9e-47 161.9 0.1 1.5 1 0 0 1 1 1 1 Rough deal protein C-terminal region SNF2_N PF00176.23 KXS20916.1 - 2.9e-54 184.1 0.0 5.2e-54 183.3 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KXS20916.1 - 7e-13 48.9 0.0 1.4e-12 47.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXS20916.1 - 8e-12 45.5 0.0 1.7e-11 44.5 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 KXS20916.1 - 0.0024 17.1 0.0 0.0064 15.7 0.0 1.7 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 NAD_binding_1 PF00175.21 KXS20917.1 - 5e-05 23.9 0.0 0.014 16.0 0.0 2.5 2 1 0 2 2 2 2 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 KXS20917.1 - 0.08 13.1 0.0 14 5.8 0.0 2.2 2 0 0 2 2 2 0 Ferric reductase NAD binding domain peroxidase PF00141.23 KXS20918.1 - 2.7e-32 112.3 0.0 5.5e-32 111.3 0.0 1.5 1 1 0 1 1 1 1 Peroxidase ESCRT-II PF05871.12 KXS20920.1 - 1.3e-35 122.7 0.0 1.6e-35 122.4 0.0 1.1 1 0 0 1 1 1 1 ESCRT-II complex subunit LptE PF04390.12 KXS20920.1 - 0.17 12.6 0.0 0.24 12.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide-assembly F-box-like PF12937.7 KXS20921.1 - 3.3e-06 26.9 0.4 9.8e-06 25.4 0.1 2.0 2 0 0 2 2 2 1 F-box-like Kri1_C PF12936.7 KXS20922.1 - 2.9e-23 81.8 0.2 2.9e-23 81.8 0.2 5.4 6 1 1 7 7 7 1 KRI1-like family C-terminal Kri1 PF05178.12 KXS20922.1 - 3.2e-18 66.2 8.5 3.2e-18 66.2 8.5 6.5 7 0 0 7 7 7 1 KRI1-like family BCS1_N PF08740.11 KXS20923.1 - 5.2e-26 91.8 0.0 7.7e-26 91.2 0.0 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 KXS20923.1 - 1.4e-14 54.7 0.0 2.6e-06 27.9 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 KXS20923.1 - 0.0051 16.0 0.0 0.011 15.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) YitT_membrane PF02588.15 KXS20923.1 - 0.039 13.3 0.6 0.072 12.4 0.6 1.4 1 0 0 1 1 1 0 Uncharacterised 5xTM membrane BCR, YitT family COG1284 AAA_16 PF13191.6 KXS20923.1 - 0.053 13.9 1.5 0.13 12.6 0.1 2.3 2 1 0 2 2 2 0 AAA ATPase domain RsgA_GTPase PF03193.16 KXS20923.1 - 0.085 12.7 0.0 0.21 11.5 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase Dala_Dala_lig_C PF07478.13 KXS20925.1 - 2.4e-12 46.8 0.0 1.2e-11 44.5 0.0 1.9 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus CPSase_L_D2 PF02786.17 KXS20925.1 - 0.0015 18.0 0.0 0.0032 17.0 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain GARS_A PF01071.19 KXS20925.1 - 0.012 15.3 0.0 0.02 14.7 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain DUF3626 PF12294.8 KXS20926.1 - 8.2e-124 412.5 0.0 1e-123 412.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3626) Polyketide_cyc2 PF10604.9 KXS20926.1 - 1.3e-08 35.2 0.0 3.5e-08 33.8 0.0 1.7 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport adh_short PF00106.25 KXS20927.1 - 1.5e-27 96.3 0.0 2.5e-27 95.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXS20927.1 - 4.1e-17 62.5 0.0 7.8e-17 61.6 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXS20927.1 - 0.0079 16.1 0.1 0.032 14.2 0.1 1.9 1 1 0 1 1 1 1 KR domain GTP_cyclohydro2 PF00925.20 KXS20927.1 - 0.18 11.4 0.0 0.29 10.7 0.0 1.4 1 0 0 1 1 1 0 GTP cyclohydrolase II IRK_C PF17655.1 KXS20929.1 - 1.8e-23 83.0 0.0 2.8e-23 82.4 0.0 1.2 1 0 0 1 1 1 1 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 KXS20929.1 - 1e-07 31.9 1.5 6e-06 26.1 0.1 2.3 2 0 0 2 2 2 2 Inward rectifier potassium channel transmembrane domain Ion_trans_2 PF07885.16 KXS20929.1 - 1.1e-05 25.3 8.1 2.2e-05 24.3 7.4 1.8 1 1 1 2 2 2 1 Ion channel FMO-like PF00743.19 KXS20930.1 - 2.8e-26 92.1 1.1 1.2e-14 53.7 0.0 3.8 1 1 2 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KXS20930.1 - 1.5e-11 44.1 0.5 7.6e-07 28.7 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXS20930.1 - 7e-08 32.6 0.6 2.5e-07 30.8 0.3 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXS20930.1 - 6.6e-07 28.9 1.2 0.031 13.5 1.8 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXS20930.1 - 0.00025 20.3 0.3 0.0072 15.6 0.2 2.2 2 0 0 2 2 2 1 Thi4 family K_oxygenase PF13434.6 KXS20930.1 - 0.00068 18.9 0.1 0.0094 15.1 0.0 2.4 2 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Amino_oxidase PF01593.24 KXS20930.1 - 0.00091 18.6 0.1 0.0014 18.0 0.1 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 KXS20930.1 - 0.0014 19.1 0.8 0.9 10.1 1.5 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXS20930.1 - 0.0014 18.2 2.8 0.0026 17.4 2.8 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KXS20930.1 - 0.011 14.9 2.0 0.011 14.9 2.0 1.4 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.14 KXS20930.1 - 0.014 14.1 1.3 0.024 13.4 1.3 1.3 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.19 KXS20930.1 - 0.028 13.7 0.5 0.21 10.8 0.2 2.0 2 0 0 2 2 2 0 FAD binding domain Glu_dehyd_C PF16912.5 KXS20930.1 - 0.064 12.7 0.0 0.65 9.4 0.0 2.1 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 KXS20930.1 - 0.099 11.9 0.8 0.21 10.9 0.8 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 KXS20930.1 - 0.13 12.3 0.0 4.5 7.4 0.0 2.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 KXS20930.1 - 0.19 12.0 0.2 0.46 10.8 0.2 1.7 1 0 0 1 1 1 0 TrkA-N domain Mfa1 PF17445.2 KXS20931.1 - 0.11 12.5 1.3 0.48 10.5 1.3 2.1 1 0 0 1 1 1 0 Mating factor A1 IQ PF00612.27 KXS20932.1 - 0.0054 16.4 3.0 0.016 14.9 3.0 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif SKA2 PF16740.5 KXS20932.1 - 0.056 13.2 2.1 1.4 8.8 0.3 2.4 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 DUF3584 PF12128.8 KXS20932.1 - 0.13 9.8 22.7 0.18 9.3 22.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF1664 PF07889.12 KXS20932.1 - 0.28 11.2 5.4 0.8 9.8 0.8 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) UPF0242 PF06785.11 KXS20932.1 - 0.88 9.6 9.4 1.7 8.7 9.4 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Apolipoprotein PF01442.18 KXS20932.1 - 1.2 8.9 38.0 0.022 14.6 17.8 2.6 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain DUF713 PF05218.14 KXS20932.1 - 2.1 8.1 11.2 0.67 9.7 1.7 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF713) DUF4618 PF15397.6 KXS20932.1 - 3.1 7.1 10.1 4.1 6.7 1.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) K-box PF01486.17 KXS20932.1 - 3.2 8.0 7.0 9 6.6 0.8 2.9 3 0 0 3 3 3 0 K-box region CC2-LZ PF16516.5 KXS20932.1 - 5.2 7.5 14.3 55 4.2 14.0 2.5 1 1 1 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator BTB PF00651.31 KXS20934.1 - 9.6e-05 22.6 0.0 0.00015 22.0 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain Pkinase_Tyr PF07714.17 KXS20935.1 - 5.5e-27 94.7 0.0 1e-13 51.2 0.0 2.6 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXS20935.1 - 7.2e-24 84.6 0.0 2.5e-11 43.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain APH PF01636.23 KXS20935.1 - 0.00019 21.4 0.1 0.0074 16.2 0.0 2.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXS20935.1 - 0.044 12.6 0.0 0.065 12.0 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase CTP_transf_like PF01467.26 KXS20935.1 - 0.14 12.4 0.0 0.82 9.9 0.0 2.1 2 0 0 2 2 2 0 Cytidylyltransferase-like DEAD PF00270.29 KXS20937.1 - 6.4e-19 68.4 0.0 1.4e-18 67.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXS20937.1 - 4e-15 56.1 0.0 1.5e-14 54.3 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF1998 PF09369.10 KXS20937.1 - 6.5e-15 55.7 1.9 3.9e-14 53.2 2.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF1998) ResIII PF04851.15 KXS20937.1 - 5.2e-06 26.6 0.0 8.4e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PAM2 PF07145.15 KXS20938.1 - 0.00067 19.2 0.8 0.00067 19.2 0.8 2.4 2 0 0 2 2 2 1 Ataxin-2 C-terminal region p450 PF00067.22 KXS20939.1 - 1.2e-66 225.4 0.0 2e-66 224.7 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 ERG4_ERG24 PF01222.17 KXS20940.1 - 2.9e-82 276.7 13.6 1e-81 274.9 13.6 1.7 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF2304 PF10066.9 KXS20940.1 - 0.11 12.7 0.3 1.1 9.5 0.0 2.7 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2304) NUDIX PF00293.28 KXS20941.1 - 1.4e-10 41.3 0.0 3e-10 40.3 0.0 1.5 2 0 0 2 2 2 1 NUDIX domain PAM2 PF07145.15 KXS20943.1 - 0.01 15.5 4.8 2.1 8.2 2.1 2.5 2 0 0 2 2 2 0 Ataxin-2 C-terminal region NmrA PF05368.13 KXS20944.1 - 2.7e-16 59.8 0.0 4.1e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXS20944.1 - 1.8e-11 44.2 0.1 1.6e-10 41.2 0.1 2.3 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KXS20944.1 - 0.0017 17.9 0.1 0.0041 16.6 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KXS20944.1 - 0.066 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 KR domain 3Beta_HSD PF01073.19 KXS20944.1 - 0.2 10.7 0.0 0.44 9.5 0.0 1.6 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family CTD_bind PF04818.13 KXS20945.1 - 4e-08 34.0 0.1 6.9e-08 33.2 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase II-binding domain. Acyltransf_C PF16076.5 KXS20946.1 - 5.2e-09 36.1 0.0 2.4e-07 30.7 0.0 2.4 2 0 0 2 2 2 1 Acyltransferase C-terminus Acyltransferase PF01553.21 KXS20946.1 - 3.8e-05 23.3 0.0 5e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase DUF2981 PF11200.8 KXS20946.1 - 0.029 14.1 0.0 0.036 13.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) BatD PF13584.6 KXS20948.1 - 0.19 10.5 0.4 0.32 9.8 0.4 1.4 1 0 0 1 1 1 0 Oxygen tolerance Pox_A14 PF05767.12 KXS20948.1 - 0.19 11.9 2.5 0.99 9.6 0.1 2.2 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 PGG PF13962.6 KXS20948.1 - 2.4 8.0 7.9 0.062 13.1 1.3 1.7 2 0 0 2 2 2 0 Domain of unknown function Neurokinin_B PF03823.14 KXS20948.1 - 3.1 7.9 5.2 16 5.6 0.0 2.5 2 0 0 2 2 2 0 Neurokinin B Tetraspanin PF00335.20 KXS20948.1 - 4.5 6.9 10.0 1.1 8.9 4.5 2.0 2 0 0 2 2 2 0 Tetraspanin family Y_phosphatase PF00102.27 KXS20949.1 - 1.3e-55 188.6 0.0 1.9e-55 188.0 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Rhodanese PF00581.20 KXS20949.1 - 3.1e-08 34.1 0.0 7.5e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain DSPc PF00782.20 KXS20949.1 - 0.058 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain SET PF00856.28 KXS20950.1 - 0.00015 22.2 0.1 0.00055 20.4 0.1 1.5 1 1 1 2 2 2 1 SET domain EHN PF06441.12 KXS20951.1 - 6.4e-34 116.6 0.1 1.4e-33 115.5 0.1 1.6 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KXS20951.1 - 3.1e-18 66.3 0.3 3.1e-18 66.3 0.3 1.8 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXS20951.1 - 0.052 14.2 10.9 0.015 15.9 7.2 2.0 2 1 0 2 2 2 0 Alpha/beta hydrolase family Pectate_lyase PF03211.13 KXS20953.1 - 3e-49 167.3 0.1 3.8e-49 167.0 0.1 1.1 1 0 0 1 1 1 1 Pectate lyase COesterase PF00135.28 KXS20954.1 - 1.8e-83 281.1 0.0 2.9e-83 280.5 0.0 1.3 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXS20954.1 - 1.3e-12 48.0 0.4 5e-06 26.5 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KXS20954.1 - 0.00079 19.0 0.1 0.0014 18.2 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 KXS20954.1 - 0.033 13.8 0.0 0.059 13.0 0.0 1.3 1 0 0 1 1 1 0 Putative esterase DUF3712 PF12505.8 KXS20958.1 - 1.2e-37 129.0 23.4 1.7e-26 92.9 0.8 5.2 4 2 0 4 4 4 3 Protein of unknown function (DUF3712) LEA_2 PF03168.13 KXS20958.1 - 1.1e-05 25.9 16.7 0.11 13.0 0.0 5.7 6 0 0 6 6 6 3 Late embryogenesis abundant protein VIT PF08487.10 KXS20958.1 - 0.016 15.4 0.3 2.3 8.4 0.0 2.7 2 0 0 2 2 2 0 Vault protein inter-alpha-trypsin domain MG1 PF17790.1 KXS20958.1 - 0.25 11.8 0.9 7.4 7.1 0.1 3.3 3 0 0 3 3 3 0 Macroglobulin domain MG1 NPR1_like_C PF12313.8 KXS20958.1 - 0.27 10.8 0.0 0.65 9.5 0.0 1.5 1 0 0 1 1 1 0 NPR1/NIM1 like defence protein C terminal MFMR_assoc PF16596.5 KXS20958.1 - 8.6 6.8 8.1 3.5 8.1 0.4 3.0 3 0 0 3 3 3 0 Disordered region downstream of MFMR AA_permease PF00324.21 KXS20959.1 - 3.8e-71 240.1 15.5 1.4e-63 215.2 14.6 2.6 2 1 0 2 2 2 2 Amino acid permease AA_permease_2 PF13520.6 KXS20959.1 - 9.1e-22 77.5 13.2 1.5e-21 76.7 13.2 1.3 1 0 0 1 1 1 1 Amino acid permease Peptidase_M15_4 PF13539.6 KXS20959.1 - 0.044 14.3 0.8 0.59 10.7 0.0 2.7 2 0 0 2 2 2 0 D-alanyl-D-alanine carboxypeptidase adh_short PF00106.25 KXS20960.1 - 2.3e-18 66.4 1.0 9.8e-18 64.3 0.7 1.8 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXS20960.1 - 4.8e-09 36.1 0.1 2.4e-08 33.8 0.1 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXS20960.1 - 3.9e-06 26.9 1.1 7.3e-06 26.0 1.1 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KXS20960.1 - 7.3e-06 25.6 0.1 1.4e-05 24.7 0.0 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family LRR_4 PF12799.7 KXS20962.1 - 1.3e-09 38.2 19.4 9.6e-05 22.7 3.0 2.9 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXS20962.1 - 1.1e-07 31.5 5.5 1.1e-07 31.5 5.5 2.7 2 1 1 3 3 3 2 Leucine rich repeat Phage_Coat_B PF05356.11 KXS20962.1 - 0.047 13.6 1.2 0.11 12.4 0.4 2.0 2 0 0 2 2 2 0 Phage Coat protein B LRR_1 PF00560.33 KXS20962.1 - 0.58 10.9 8.9 70 4.6 0.2 4.8 4 1 0 4 4 4 0 Leucine Rich Repeat FH2 PF02181.23 KXS20963.1 - 2e-68 231.2 3.4 2.4e-68 230.9 3.4 1.1 1 0 0 1 1 1 1 Formin Homology 2 Domain Cytochrom_B562 PF07361.11 KXS20963.1 - 0.007 17.0 4.8 0.13 12.9 0.9 3.2 3 1 1 4 4 4 1 Cytochrome b562 VAPB_antitox PF02697.14 KXS20963.1 - 0.045 14.5 1.4 0.75 10.6 0.7 2.8 2 0 0 2 2 2 0 Putative antitoxin Rotamase PF00639.21 KXS20963.1 - 0.12 13.4 3.1 3.6 8.6 0.1 2.8 3 1 0 3 3 3 0 PPIC-type PPIASE domain BMFP PF04380.13 KXS20963.1 - 0.12 12.9 2.0 10 6.6 0.1 3.2 3 0 0 3 3 3 0 Membrane fusogenic activity Drf_GBD PF06371.13 KXS20964.1 - 3.7e-34 117.9 1.5 6.3e-34 117.2 1.5 1.3 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 KXS20964.1 - 8.1e-10 38.6 0.0 2.4e-09 37.1 0.0 1.8 1 0 0 1 1 1 1 Diaphanous FH3 Domain Tuberin PF03542.16 KXS20964.1 - 0.23 10.5 2.4 1.8 7.6 0.1 2.3 1 1 1 2 2 2 0 Tuberin DPBB_1 PF03330.18 KXS20965.1 - 0.0012 19.1 0.0 0.0028 17.9 0.0 1.7 1 0 0 1 1 1 1 Lytic transglycolase TM_PBP2_N PF16296.5 KXS20967.1 - 0.00085 19.4 0.3 0.0012 19.0 0.3 1.2 1 0 0 1 1 1 1 N-terminal of TM subunit in PBP-dependent ABC transporters Spore_III_AF PF09581.10 KXS20967.1 - 0.1 12.6 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) DUF4834 PF16118.5 KXS20967.1 - 0.24 12.4 0.3 0.32 12.0 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) IF4E PF01652.18 KXS20968.1 - 1.1e-46 158.6 0.0 1.3e-46 158.3 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Arf PF00025.21 KXS20969.1 - 1.2e-44 151.9 0.0 1.5e-44 151.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 KXS20969.1 - 1e-12 48.0 0.0 1.3e-12 47.6 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 KXS20969.1 - 1.1e-12 47.8 0.0 1.5e-07 30.9 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 KXS20969.1 - 7.9e-12 45.5 0.0 1.4e-11 44.7 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KXS20969.1 - 3.5e-08 33.1 0.0 5e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KXS20969.1 - 2.5e-07 30.3 0.0 2.9e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KXS20969.1 - 5.9e-06 26.0 0.0 0.00094 18.8 0.0 2.0 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KXS20969.1 - 2e-05 24.6 0.0 3.2e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_18 PF13238.6 KXS20969.1 - 0.0044 17.6 0.0 0.02 15.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_23 PF13476.6 KXS20969.1 - 0.01 16.4 0.0 0.014 15.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KXS20969.1 - 0.04 13.7 0.0 0.077 12.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain BRCT_2 PF16589.5 KXS20970.1 - 3.1e-10 40.3 0.0 6.3e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 KXS20970.1 - 2.6e-07 30.9 0.2 9.2e-07 29.2 0.0 2.0 2 1 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 KXS20970.1 - 0.0011 18.9 1.4 0.0042 17.0 1.4 2.0 1 1 0 1 1 1 1 twin BRCT domain LIG3_BRCT PF16759.5 KXS20970.1 - 0.0012 19.1 0.0 0.0025 18.1 0.0 1.6 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain zf-C3HC4_2 PF13923.6 KXS20972.1 - 3e-07 30.1 7.0 4.7e-07 29.5 7.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXS20972.1 - 9e-07 29.1 6.8 1.4e-06 28.6 6.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KXS20972.1 - 1.5e-06 28.0 6.7 2.3e-06 27.4 6.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KXS20972.1 - 0.00018 21.3 5.3 0.00027 20.7 5.3 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ubiquitin PF00240.23 KXS20972.1 - 0.00088 19.0 0.0 0.0016 18.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Prok-RING_4 PF14447.6 KXS20972.1 - 0.00089 19.1 7.6 0.0024 17.7 7.9 1.6 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 KXS20972.1 - 0.001 19.3 5.1 0.0021 18.3 5.1 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KXS20972.1 - 0.0022 18.0 2.1 0.0022 18.0 2.1 1.8 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_10 PF16685.5 KXS20972.1 - 0.0079 16.3 2.8 0.014 15.5 2.8 1.4 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-RING_5 PF14634.6 KXS20972.1 - 0.0092 15.9 9.6 0.025 14.5 9.9 1.6 1 1 1 2 2 2 1 zinc-RING finger domain RAWUL PF16207.5 KXS20972.1 - 0.016 15.9 0.0 0.029 15.0 0.0 1.4 1 0 0 1 1 1 0 RAWUL domain RING finger- and WD40-associated ubiquitin-like zf-C3HC4_4 PF15227.6 KXS20972.1 - 0.025 14.7 7.4 0.049 13.8 7.4 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 KXS20972.1 - 0.03 14.2 4.7 0.053 13.4 4.7 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DUF4428 PF14471.6 KXS20972.1 - 0.075 13.0 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) zinc-ribbons_6 PF07191.12 KXS20972.1 - 0.18 11.8 2.1 0.3 11.1 2.1 1.3 1 0 0 1 1 1 0 zinc-ribbons zf-Nse PF11789.8 KXS20972.1 - 0.23 11.3 2.9 0.41 10.5 2.9 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-P11 PF03854.14 KXS20972.1 - 0.53 10.0 4.8 1.2 8.8 4.8 1.6 1 0 0 1 1 1 0 P-11 zinc finger 2-Hacid_dh_C PF02826.19 KXS20973.1 - 1.3e-43 148.4 0.0 1.8e-43 148.0 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KXS20973.1 - 0.00041 20.0 0.0 0.00053 19.6 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KXS20973.1 - 0.00057 20.1 0.0 0.00094 19.4 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 KXS20973.1 - 0.014 14.9 0.0 0.022 14.3 0.0 1.2 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain F420_oxidored PF03807.17 KXS20973.1 - 0.037 14.6 0.0 0.072 13.7 0.0 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Annexin PF00191.20 KXS20974.1 - 2.7e-27 94.6 1.5 5.8e-11 42.3 0.1 3.9 4 0 0 4 4 4 3 Annexin HNH_2 PF13391.6 KXS20975.1 - 0.0039 17.3 0.0 0.0083 16.2 0.0 1.5 1 0 0 1 1 1 1 HNH endonuclease Vwaint PF14624.6 KXS20977.1 - 3.7e-18 65.4 0.2 1.1e-17 64.0 0.4 1.6 2 0 0 2 2 2 1 VWA / Hh protein intein-like Vint PF14623.6 KXS20977.1 - 2.1e-16 60.2 0.3 4.3e-16 59.2 0.1 1.7 2 0 0 2 2 2 1 Hint-domain VWA_2 PF13519.6 KXS20977.1 - 4.5e-16 59.4 0.0 1.5e-15 57.7 0.0 1.9 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.28 KXS20977.1 - 3.3e-13 50.3 0.0 6e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 KXS20977.1 - 3e-06 27.2 0.0 2.5e-05 24.3 0.0 2.1 1 1 0 1 1 1 1 von Willebrand factor type A domain Pectate_lyase PF03211.13 KXS20978.1 - 3.1e-39 134.6 0.1 9e-29 100.5 0.0 2.1 1 1 1 2 2 2 2 Pectate lyase YqeY PF09424.10 KXS20979.1 - 1.8e-28 99.4 0.5 2.1e-28 99.2 0.5 1.1 1 0 0 1 1 1 1 Yqey-like protein Peptidase_S68 PF10461.9 KXS20979.1 - 0.079 13.2 0.2 2 8.7 0.1 2.7 2 0 0 2 2 2 0 Peptidase S68 DUF1376 PF07120.11 KXS20979.1 - 0.1 12.9 0.0 0.95 9.8 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1376) DprA_WH PF17782.1 KXS20979.1 - 0.27 11.4 2.2 2 8.6 0.5 2.5 2 0 0 2 2 2 0 DprA winged helix domain Pterin_4a PF01329.19 KXS20981.1 - 7.5e-29 99.7 0.2 1.2e-28 99.1 0.2 1.3 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase ISK_Channel PF02060.15 KXS20981.1 - 0.11 12.3 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Slow voltage-gated potassium channel Fungal_trans PF04082.18 KXS20982.1 - 1.2e-10 40.9 0.1 2e-10 40.2 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXS20982.1 - 0.0046 17.1 5.3 0.0046 17.1 5.3 2.2 2 1 1 3 3 3 2 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_16 PF13432.6 KXS20983.1 - 1.5e-10 41.5 10.0 4.3e-06 27.3 0.3 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KXS20983.1 - 6.2e-10 39.1 15.8 0.0007 20.2 0.2 5.3 1 1 4 5 5 5 5 Tetratricopeptide repeat TPR_2 PF07719.17 KXS20983.1 - 1.5e-09 37.3 3.5 0.0072 16.4 0.1 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 KXS20983.1 - 3.7e-09 36.1 0.5 0.012 15.8 0.0 3.7 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_6 PF13174.6 KXS20983.1 - 9e-07 29.1 1.8 0.37 11.5 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 KXS20983.1 - 1.3e-06 28.6 5.4 0.021 15.1 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KXS20983.1 - 2.7e-06 27.8 10.6 0.078 13.5 0.1 4.7 1 1 5 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 KXS20983.1 - 1.3e-05 24.8 2.0 0.0036 17.1 0.0 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 KXS20983.1 - 4.2e-05 23.3 1.3 0.26 11.4 0.1 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 KXS20983.1 - 0.00013 22.1 0.7 0.066 13.6 0.0 4.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 KXS20983.1 - 0.0013 18.4 0.1 0.073 12.8 0.1 2.6 2 0 0 2 2 2 1 TPR repeat YfiO PF13525.6 KXS20983.1 - 0.0046 16.7 0.1 0.13 11.9 0.0 2.3 1 1 0 2 2 2 1 Outer membrane lipoprotein TPR_9 PF13371.6 KXS20983.1 - 0.03 14.5 9.7 0.063 13.4 1.3 2.9 2 1 0 2 2 2 0 Tetratricopeptide repeat DUF5133 PF17196.4 KXS20983.1 - 0.04 14.1 1.2 64 3.8 0.0 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF5133) FRG2 PF15315.6 KXS20983.1 - 0.053 13.7 0.2 0.082 13.1 0.2 1.2 1 0 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 Sel1 PF08238.12 KXS20984.1 - 2.4e-44 148.8 32.2 2.6e-07 31.1 0.0 10.5 10 1 0 10 10 10 8 Sel1 repeat TPR_6 PF13174.6 KXS20984.1 - 0.00015 22.1 13.4 21 6.0 0.0 8.1 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_7 PF13176.6 KXS20984.1 - 0.0018 18.1 3.8 0.57 10.3 0.0 5.7 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 KXS20984.1 - 0.0084 16.7 14.6 4.8 7.9 0.1 7.5 6 2 2 8 8 8 1 Tetratricopeptide repeat TPR_2 PF07719.17 KXS20984.1 - 0.074 13.2 14.7 3.7 7.9 1.1 6.9 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_1 PF00515.28 KXS20984.1 - 0.33 10.9 11.3 4.6 7.2 1.2 6.3 8 0 0 8 8 8 0 Tetratricopeptide repeat mRNA_triPase PF02940.15 KXS20985.1 - 2.2e-36 125.7 0.0 2.8e-36 125.3 0.0 1.1 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain CBM_2 PF00553.19 KXS20986.1 - 0.0018 18.6 2.5 0.0045 17.3 2.5 1.7 1 0 0 1 1 1 1 Cellulose binding domain Polysacc_deac_1 PF01522.21 KXS20986.1 - 0.016 15.1 0.3 0.067 13.1 0.3 1.9 1 1 0 1 1 1 0 Polysaccharide deacetylase eIF-3c_N PF05470.12 KXS20987.1 - 1.3e-189 631.4 10.5 1.3e-189 631.4 10.5 4.0 2 1 1 3 3 3 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 KXS20987.1 - 1.9e-13 50.8 0.1 1.1e-12 48.3 0.0 2.2 2 0 0 2 2 2 1 PCI domain Rota_NSP4 PF01452.16 KXS20987.1 - 0.19 11.4 0.9 26 4.5 0.2 2.6 2 0 0 2 2 2 0 Rotavirus non structural protein DSBA PF01323.20 KXS20988.1 - 1.9e-36 125.6 0.0 2.2e-36 125.5 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_5 PF13743.6 KXS20988.1 - 0.00036 20.3 0.0 0.00048 19.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_4 PF13462.6 KXS20988.1 - 0.034 14.3 0.0 0.53 10.4 0.0 2.3 1 1 2 3 3 3 0 Thioredoxin LsmAD PF06741.13 KXS20989.1 - 1.5e-24 86.3 3.9 2.5e-24 85.6 3.9 1.3 1 0 0 1 1 1 1 LsmAD domain SM-ATX PF14438.6 KXS20989.1 - 2.1e-16 59.8 0.0 3.8e-16 59.0 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain WD40 PF00400.32 KXS20990.1 - 4.4e-34 115.9 3.6 1.8e-07 31.7 0.3 6.6 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXS20990.1 - 8.4e-25 86.9 0.2 0.0018 18.5 0.0 6.5 1 1 6 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KXS20990.1 - 2.8e-11 43.7 0.0 8.1e-05 22.6 0.0 3.1 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 KXS20990.1 - 5.1e-06 25.3 0.0 0.0046 15.5 0.0 2.2 1 1 1 2 2 2 2 Cytochrome D1 heme domain WD40_like PF17005.5 KXS20990.1 - 6.3e-05 22.5 0.1 0.057 12.7 0.0 3.0 1 1 2 3 3 3 2 WD40-like domain PD40 PF07676.12 KXS20990.1 - 8.7e-05 22.3 0.0 0.45 10.5 0.0 2.9 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat BBS2_Mid PF14783.6 KXS20990.1 - 0.00083 19.4 0.1 2.6 8.1 0.0 3.3 3 0 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region HPS3_N PF14761.6 KXS20990.1 - 0.004 16.7 0.0 8.9 5.8 0.0 3.1 1 1 1 3 3 3 1 Hermansky-Pudlak syndrome 3 DUF1308 PF07000.11 KXS20990.1 - 0.0094 15.9 0.0 0.09 12.7 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1308) MMS1_N PF10433.9 KXS20990.1 - 0.016 13.9 0.0 0.042 12.5 0.0 1.8 1 1 0 1 1 1 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term Coatomer_WDAD PF04053.14 KXS20990.1 - 0.044 12.8 0.1 3.1 6.7 0.0 2.7 2 1 1 3 3 3 0 Coatomer WD associated region RAB3GAP2_N PF14655.6 KXS20990.1 - 0.052 12.8 0.0 0.81 8.9 0.0 2.4 2 1 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Lactonase PF10282.9 KXS20990.1 - 0.1 11.9 0.0 4.6 6.4 0.0 2.3 1 1 0 2 2 2 0 Lactonase, 7-bladed beta-propeller Dynamin_M PF01031.20 KXS20991.1 - 2.6e-106 355.0 0.0 4.7e-106 354.2 0.0 1.4 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 KXS20991.1 - 3e-54 183.6 0.0 7e-54 182.4 0.0 1.7 2 0 0 2 2 2 1 Dynamin family GED PF02212.18 KXS20991.1 - 1.3e-27 95.8 2.9 3.5e-27 94.4 2.9 1.8 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KXS20991.1 - 4e-05 23.7 0.2 0.44 10.6 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_15 PF13175.6 KXS20991.1 - 0.017 14.9 1.9 4.1 7.0 0.0 2.7 3 0 0 3 3 3 0 AAA ATPase domain FeoB_N PF02421.18 KXS20991.1 - 0.13 11.8 1.0 11 5.6 0.1 2.6 3 0 0 3 3 3 0 Ferrous iron transport protein B DRIM PF07539.12 KXS20992.1 - 4.2e-146 487.8 7.4 4.2e-146 487.8 7.4 4.3 4 1 0 4 4 4 2 Down-regulated in metastasis SNARE PF05739.19 KXS20993.1 - 3.7e-16 58.8 0.4 3.7e-16 58.8 0.4 1.8 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.25 KXS20993.1 - 5.9e-08 32.6 11.9 1.4e-07 31.4 11.9 1.6 1 1 0 1 1 1 1 Syntaxin Med30 PF11315.8 KXS20993.1 - 0.0091 16.2 1.6 0.0091 16.2 1.6 2.1 1 1 1 2 2 2 1 Mediator complex subunit 30 GCP_C_terminal PF04130.13 KXS20993.1 - 0.018 14.6 3.0 0.026 14.0 2.3 1.5 1 1 0 1 1 1 0 Gamma tubulin complex component C-terminal PalH PF08733.10 KXS20993.1 - 0.022 13.8 0.1 0.037 13.0 0.1 1.3 1 0 0 1 1 1 0 PalH/RIM21 ODV-E18 PF10717.9 KXS20993.1 - 0.034 14.0 0.1 0.079 12.8 0.1 1.5 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Syntaxin_2 PF14523.6 KXS20993.1 - 0.037 14.4 13.2 0.045 14.1 6.7 2.7 2 1 1 3 3 3 0 Syntaxin-like protein MCPsignal PF00015.21 KXS20993.1 - 0.051 13.4 3.2 0.14 12.0 0.5 2.3 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain PEP-utilisers_N PF05524.13 KXS20993.1 - 0.14 12.4 4.3 0.7 10.1 0.4 2.9 2 1 0 2 2 2 0 PEP-utilising enzyme, N-terminal MobC PF05713.11 KXS20993.1 - 0.7 10.4 5.2 1.1 9.7 0.0 3.3 4 0 0 4 4 3 0 Bacterial mobilisation protein (MobC) DASH_Dam1 PF08653.10 KXS20993.1 - 1.5 8.7 3.0 28 4.6 0.2 2.9 3 0 0 3 3 3 0 DASH complex subunit Dam1 MutS_III PF05192.18 KXS20993.1 - 1.8 8.8 11.3 4.5 7.4 11.3 1.7 1 1 0 1 1 1 0 MutS domain III DNA_repr_REX1B PF14966.6 KXS20993.1 - 3.5 8.3 6.6 1.1 10.0 2.0 2.5 2 1 1 3 3 3 0 DNA repair REX1-B NPV_P10 PF05531.12 KXS20993.1 - 9.2 6.8 9.5 27 5.3 0.7 3.2 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF2203 PF09969.9 KXS20993.1 - 9.3 7.0 7.9 34 5.2 1.1 2.7 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) MFS_1 PF07690.16 KXS20994.1 - 2.3e-28 99.1 21.5 3.6e-28 98.5 21.5 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily AAA_lid_11 PF18198.1 KXS20994.1 - 0.2 11.5 0.0 0.32 10.8 0.0 1.3 1 0 0 1 1 1 0 Dynein heavy chain AAA lid domain DMAP1 PF05499.12 KXS20995.1 - 6.2e-08 32.7 3.5 2.8e-06 27.3 0.4 2.2 2 0 0 2 2 2 2 DNA methyltransferase 1-associated protein 1 (DMAP1) BORCS8 PF10167.9 KXS20995.1 - 0.053 13.5 0.6 0.094 12.7 0.6 1.4 1 0 0 1 1 1 0 BLOC-1-related complex sub-unit 8 PseudoU_synth_1 PF01416.20 KXS20995.1 - 0.094 13.2 0.4 3.4 8.2 0.2 2.4 2 0 0 2 2 2 0 tRNA pseudouridine synthase APG6_N PF17675.1 KXS20995.1 - 5.6 7.5 9.6 3.9 8.0 2.7 2.3 2 1 0 2 2 2 0 Apg6 coiled-coil region NTF2 PF02136.20 KXS20996.1 - 5.8e-22 78.5 0.0 6.4e-22 78.4 0.0 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain UPF1_Zn_bind PF09416.10 KXS20997.1 - 6.1e-69 230.8 0.1 8.5e-69 230.4 0.1 1.2 1 0 0 1 1 1 1 RNA helicase (UPF2 interacting domain) DUF5599 PF18141.1 KXS20997.1 - 3.1e-20 72.2 0.0 6.1e-20 71.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5599) AAA_12 PF13087.6 KXS20998.1 - 1.1e-60 204.7 0.0 1.5e-60 204.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KXS20998.1 - 3e-17 63.3 0.0 4.3e-17 62.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 KXS20998.1 - 5e-05 23.2 0.0 0.043 13.5 0.0 2.2 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 KXS20998.1 - 0.011 15.5 0.0 0.018 14.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain Ribosomal_S13_N PF08069.12 KXS20998.1 - 0.066 13.3 0.0 0.18 11.9 0.0 1.7 1 0 0 1 1 1 0 Ribosomal S13/S15 N-terminal domain PIF1 PF05970.14 KXS20998.1 - 0.098 11.8 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase EphA2_TM PF14575.6 KXS20998.1 - 0.13 13.2 0.0 0.23 12.4 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Pkinase PF00069.25 KXS21000.1 - 1e-58 198.8 0.0 1.2e-58 198.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS21000.1 - 2.6e-29 102.3 0.0 3.2e-29 102.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXS21000.1 - 2.3e-08 33.7 0.0 3.3e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KXS21000.1 - 1.4e-06 27.5 0.2 2.1e-06 27.0 0.2 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KXS21000.1 - 0.00063 19.2 0.2 0.0011 18.3 0.2 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 KXS21000.1 - 0.014 14.4 0.0 0.029 13.4 0.0 1.5 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 KXS21000.1 - 0.015 15.2 0.0 0.22 11.4 0.1 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXS21000.1 - 0.017 13.9 0.0 0.023 13.5 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Prok-RING_1 PF14446.6 KXS21001.1 - 0.00015 21.6 4.8 0.0003 20.6 4.8 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 CCDC106 PF15794.5 KXS21001.1 - 0.00072 19.3 1.9 0.0013 18.5 1.9 1.4 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 106 C1_1 PF00130.22 KXS21001.1 - 0.0012 18.6 8.4 0.002 18.0 8.4 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.6 KXS21001.1 - 0.0017 17.8 2.7 0.0038 16.7 2.7 1.6 1 0 0 1 1 1 1 PHD-finger zf-RING_9 PF13901.6 KXS21001.1 - 0.0052 16.8 7.3 0.0052 16.8 7.3 1.7 2 0 0 2 2 2 1 Putative zinc-RING and/or ribbon HR1 PF02185.16 KXS21001.1 - 0.031 14.4 1.8 0.031 14.4 1.8 1.8 2 0 0 2 2 2 0 Hr1 repeat PHD PF00628.29 KXS21001.1 - 0.06 13.2 8.3 0.11 12.4 8.3 1.4 1 0 0 1 1 1 0 PHD-finger DUF5595 PF18077.1 KXS21001.1 - 0.11 12.6 0.2 0.25 11.4 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5595) DMAP_binding PF06464.11 KXS21001.1 - 0.12 13.2 2.4 0.21 12.4 2.4 1.6 1 1 0 1 1 1 0 DMAP1-binding Domain Occludin_ELL PF07303.13 KXS21001.1 - 0.13 13.0 1.8 0.52 11.1 0.9 2.6 1 1 1 2 2 2 0 Occludin homology domain TPR_MLP1_2 PF07926.12 KXS21001.1 - 0.2 11.7 6.8 0.079 13.0 3.3 2.1 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein LysM PF01476.20 KXS21002.1 - 1.6e-06 28.0 0.0 3.4e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 LysM domain LSM PF01423.22 KXS21003.1 - 7.6e-17 60.8 0.3 8.9e-17 60.5 0.3 1.1 1 0 0 1 1 1 1 LSM domain SHIPPO-rpt PF07004.12 KXS21004.1 - 0.00012 22.8 8.0 3.2 8.8 0.2 3.8 3 0 0 3 3 3 3 Sperm-tail PG-rich repeat Phage_Coat_A PF05357.13 KXS21004.1 - 0.058 13.2 0.3 0.098 12.5 0.3 1.3 1 0 0 1 1 1 0 Phage Coat Protein A VPS11_C PF12451.8 KXS21004.1 - 0.2 11.9 0.6 0.36 11.1 0.6 1.3 1 0 0 1 1 1 0 Vacuolar protein sorting protein 11 C terminal CC2-LZ PF16516.5 KXS21005.1 - 0.00077 19.8 1.2 0.001 19.4 1.2 1.1 1 0 0 1 1 1 1 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Phage_GP20 PF06810.11 KXS21005.1 - 0.001 18.9 0.7 0.0027 17.5 0.8 1.5 1 1 1 2 2 2 1 Phage minor structural protein GP20 Spectrin PF00435.21 KXS21005.1 - 0.0011 19.5 0.4 0.0014 19.1 0.4 1.1 1 0 0 1 1 1 1 Spectrin repeat ATG16 PF08614.11 KXS21005.1 - 0.0013 19.0 5.8 0.0016 18.7 5.8 1.0 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) BLOC1_2 PF10046.9 KXS21005.1 - 0.0018 18.5 0.4 0.0046 17.2 0.1 1.7 1 1 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 ADIP PF11559.8 KXS21005.1 - 0.0034 17.5 0.4 0.0041 17.2 0.4 1.1 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding DUF3450 PF11932.8 KXS21005.1 - 0.0047 16.3 0.1 0.0054 16.1 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) Dynamitin PF04912.14 KXS21005.1 - 0.0058 16.0 0.1 0.0067 15.8 0.1 1.0 1 0 0 1 1 1 1 Dynamitin DUF1664 PF07889.12 KXS21005.1 - 0.0065 16.5 0.1 0.0086 16.1 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) APG6_N PF17675.1 KXS21005.1 - 0.0068 16.9 2.7 0.0088 16.6 2.7 1.1 1 0 0 1 1 1 1 Apg6 coiled-coil region MAD PF05557.13 KXS21005.1 - 0.01 14.3 2.4 0.012 14.0 2.4 1.0 1 0 0 1 1 1 1 Mitotic checkpoint protein Occludin_ELL PF07303.13 KXS21005.1 - 0.015 16.1 0.5 0.024 15.4 0.5 1.3 1 0 0 1 1 1 0 Occludin homology domain THOC7 PF05615.13 KXS21005.1 - 0.015 15.5 1.4 0.023 15.0 1.4 1.2 1 0 0 1 1 1 0 Tho complex subunit 7 DUF4349 PF14257.6 KXS21005.1 - 0.016 14.6 0.5 0.019 14.4 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) TSC22 PF01166.18 KXS21005.1 - 0.018 15.3 4.9 1 9.7 0.3 2.2 2 0 0 2 2 2 0 TSC-22/dip/bun family Fez1 PF06818.15 KXS21005.1 - 0.036 14.5 1.7 0.044 14.2 1.7 1.1 1 0 0 1 1 1 0 Fez1 STAT_alpha PF01017.20 KXS21005.1 - 0.045 13.6 0.2 0.059 13.3 0.2 1.1 1 0 0 1 1 1 0 STAT protein, all-alpha domain YojJ PF10372.9 KXS21005.1 - 0.049 13.7 0.5 0.22 11.6 0.2 1.8 1 1 1 2 2 2 0 Bacterial membrane-spanning protein N-terminus FliJ PF02050.16 KXS21005.1 - 0.054 13.7 1.4 0.12 12.6 0.3 1.8 1 1 1 2 2 2 0 Flagellar FliJ protein DUF2408 PF10303.9 KXS21005.1 - 0.057 14.0 0.4 0.069 13.7 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) DivIC PF04977.15 KXS21005.1 - 0.07 12.9 1.3 1.7 8.5 0.0 2.1 1 1 1 2 2 2 0 Septum formation initiator FtsL PF04999.13 KXS21005.1 - 0.071 13.1 0.0 0.091 12.8 0.0 1.3 1 0 0 1 1 1 0 Cell division protein FtsL NPV_P10 PF05531.12 KXS21005.1 - 0.081 13.4 1.4 0.65 10.5 0.3 2.0 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein FlaC_arch PF05377.11 KXS21005.1 - 0.088 13.2 2.7 1.7 9.1 0.8 2.1 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) TraF_2 PF13729.6 KXS21005.1 - 0.096 12.0 0.0 0.1 11.9 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon, TraF, protein EzrA PF06160.12 KXS21005.1 - 0.1 10.7 1.1 0.13 10.4 1.1 1.0 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA ZapB PF06005.12 KXS21005.1 - 0.11 13.0 5.0 2.5 8.6 1.4 2.2 1 1 1 2 2 2 0 Cell division protein ZapB XhlA PF10779.9 KXS21005.1 - 0.11 12.7 2.4 1.1 9.5 0.3 2.2 1 1 1 2 2 2 0 Haemolysin XhlA PRKG1_interact PF15898.5 KXS21005.1 - 0.12 13.3 4.0 0.4 11.6 4.0 1.6 1 1 0 1 1 1 0 cGMP-dependent protein kinase interacting domain DUF2730 PF10805.8 KXS21005.1 - 0.14 12.3 1.7 0.21 11.7 1.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2730) KELK PF15796.5 KXS21005.1 - 0.16 12.5 4.6 0.59 10.6 4.7 1.8 1 1 0 1 1 1 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase HSBP1 PF06825.12 KXS21005.1 - 0.19 11.6 2.0 3 7.8 0.3 2.4 1 1 0 2 2 2 0 Heat shock factor binding protein 1 FAM76 PF16046.5 KXS21005.1 - 0.27 10.6 1.0 0.35 10.2 1.0 1.1 1 0 0 1 1 1 0 FAM76 protein Prefoldin_2 PF01920.20 KXS21005.1 - 0.57 10.2 5.3 6.1 6.8 0.3 2.1 1 1 1 2 2 2 0 Prefoldin subunit SlyX PF04102.12 KXS21005.1 - 1.2 9.8 4.4 2.4 8.8 4.3 1.6 1 1 1 2 2 2 0 SlyX TMEM70 PF06979.12 KXS21008.1 - 0.01 16.3 0.7 0.023 15.1 0.7 1.6 1 0 0 1 1 1 0 Assembly, mitochondrial proton-transport ATP synth complex DAO PF01266.24 KXS21009.1 - 3.1e-45 155.3 0.3 3.7e-45 155.1 0.3 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXS21009.1 - 0.0037 16.6 1.4 0.41 9.8 0.8 2.5 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXS21009.1 - 0.0085 15.4 1.3 0.18 11.0 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KXS21009.1 - 0.014 14.7 0.0 0.022 14.0 0.0 1.2 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase HI0933_like PF03486.14 KXS21009.1 - 0.015 14.0 0.1 0.48 9.1 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_8 PF13450.6 KXS21009.1 - 0.025 14.8 0.1 0.063 13.5 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KXS21009.1 - 0.033 13.4 0.1 0.087 12.1 0.0 1.7 2 0 0 2 2 2 0 Thi4 family NAD_binding_9 PF13454.6 KXS21009.1 - 0.16 11.9 1.1 0.63 10.0 0.2 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 KXS21009.1 - 0.2 10.7 1.4 9 5.3 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain Ank_2 PF12796.7 KXS21010.1 - 7.7e-18 64.9 0.1 7.9e-08 32.8 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXS21010.1 - 1.9e-11 44.0 3.6 2.9e-05 24.3 0.1 5.8 3 1 3 6 6 6 3 Ankyrin repeats (many copies) Ank PF00023.30 KXS21010.1 - 1.2e-09 38.2 8.2 0.0011 19.3 0.0 5.7 5 0 0 5 5 5 2 Ankyrin repeat Ank_4 PF13637.6 KXS21010.1 - 3.1e-09 37.2 4.5 6.7e-05 23.4 0.1 5.0 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXS21010.1 - 0.00012 22.2 7.4 16 6.5 0.0 5.6 5 0 0 5 5 5 2 Ankyrin repeat Beta-lactamase PF00144.24 KXS21011.1 - 8.8e-24 84.3 6.4 2.2e-23 83.1 6.4 1.6 1 1 0 1 1 1 1 Beta-lactamase DUF599 PF04654.12 KXS21014.1 - 2.4e-39 135.0 11.5 3.6e-39 134.4 11.5 1.1 1 0 0 1 1 1 1 Protein of unknown function, DUF599 Pirin PF02678.16 KXS21015.1 - 7e-31 106.4 0.6 1.1e-30 105.7 0.6 1.3 1 0 0 1 1 1 1 Pirin Cupin_2 PF07883.11 KXS21015.1 - 1.2e-06 28.2 1.7 2.2e-06 27.2 0.9 1.9 2 0 0 2 2 2 1 Cupin domain Pirin_C_2 PF17954.1 KXS21015.1 - 5.8e-06 26.4 0.0 2.2e-05 24.6 0.0 2.0 1 1 0 1 1 1 1 Quercetinase C-terminal cupin domain Cupin_3 PF05899.12 KXS21015.1 - 0.11 12.2 0.5 1.6 8.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF861) PP2C PF00481.21 KXS21016.1 - 1.8e-08 34.3 0.0 3.6e-07 30.1 0.0 2.9 3 1 0 3 3 3 1 Protein phosphatase 2C EamA PF00892.20 KXS21017.1 - 0.00033 20.8 6.4 0.00033 20.8 6.4 2.2 2 0 0 2 2 2 1 EamA-like transporter family ATP-synt_Z PF16594.5 KXS21017.1 - 0.015 14.7 2.9 0.18 11.3 0.2 2.7 2 0 0 2 2 2 0 Putative AtpZ or ATP-synthase-associated TauD PF02668.16 KXS21018.1 - 4.8e-30 105.3 0.1 6.4e-30 104.9 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 KXS21018.1 - 0.049 12.7 0.0 0.079 12.1 0.0 1.2 1 0 0 1 1 1 0 CsiD DUF1858 PF08984.11 KXS21018.1 - 0.073 13.3 0.0 1.7 8.9 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1858) PAS_3 PF08447.12 KXS21018.1 - 0.12 12.7 0.0 0.25 11.6 0.0 1.5 1 0 0 1 1 1 0 PAS fold FMN_red PF03358.15 KXS21019.1 - 9.1e-23 80.7 0.0 1.1e-22 80.5 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 KXS21019.1 - 3e-05 23.8 0.0 3.9e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold GT-D PF08759.11 KXS21019.1 - 0.11 12.2 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase GT-D fold Amidase PF01425.21 KXS21020.1 - 2.2e-75 254.3 0.1 3e-75 253.9 0.1 1.1 1 0 0 1 1 1 1 Amidase Biotin_carb_C PF02785.19 KXS21020.1 - 0.047 13.8 0.0 0.26 11.4 0.0 2.0 2 0 0 2 2 2 0 Biotin carboxylase C-terminal domain OsmC PF02566.19 KXS21021.1 - 1.8e-14 54.0 0.0 2.9e-14 53.3 0.0 1.3 1 0 0 1 1 1 1 OsmC-like protein Acetyltransf_7 PF13508.7 KXS21022.1 - 6.7e-10 39.3 0.0 9.1e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXS21022.1 - 6.1e-09 36.1 0.0 7.6e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXS21022.1 - 6.6e-09 35.8 0.0 8.1e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KXS21022.1 - 5.7e-06 26.4 0.0 6.9e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXS21022.1 - 7.4e-06 25.8 0.0 1.3e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 KXS21022.1 - 0.11 12.7 0.0 0.29 11.3 0.0 1.7 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase RSB_motif PF16294.5 KXS21023.1 - 1.5e-09 38.0 5.3 1.4e-08 34.9 0.1 2.4 2 0 0 2 2 2 2 RNSP1-SAP18 binding (RSB) motif Pinin_SDK_memA PF04696.13 KXS21023.1 - 0.034 14.2 1.7 1 9.4 0.0 2.2 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region DAO PF01266.24 KXS21024.1 - 2.4e-30 106.3 1.2 1.2e-29 104.0 1.2 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXS21024.1 - 0.00067 19.8 0.1 0.002 18.3 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KXS21024.1 - 0.001 18.4 0.2 0.0016 17.8 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 KXS21024.1 - 0.0014 19.1 0.1 0.0029 18.1 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXS21024.1 - 0.0014 17.9 0.0 0.0023 17.2 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 KXS21024.1 - 0.0016 18.0 0.1 0.0027 17.3 0.1 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AlaDh_PNT_C PF01262.21 KXS21024.1 - 0.002 17.4 0.0 0.0032 16.8 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 KXS21024.1 - 0.0032 17.4 0.0 0.0045 16.9 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Glu_dehyd_C PF16912.5 KXS21024.1 - 0.034 13.6 0.0 0.056 12.9 0.0 1.2 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus NAD_binding_7 PF13241.6 KXS21024.1 - 0.049 14.1 0.0 0.082 13.3 0.0 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding FAD_binding_2 PF00890.24 KXS21024.1 - 0.09 11.8 0.1 0.24 10.4 0.1 1.7 2 0 0 2 2 2 0 FAD binding domain ApbA PF02558.16 KXS21024.1 - 0.19 11.3 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA SHE3 PF17078.5 KXS21025.1 - 0.24 11.1 14.1 1.6 8.4 2.0 3.9 3 0 0 3 3 3 0 SWI5-dependent HO expression protein 3 Baculo_PEP_C PF04513.12 KXS21025.1 - 0.26 11.3 5.1 25 4.9 1.7 3.7 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF948 PF06103.11 KXS21025.1 - 1.6 9.1 4.5 15 5.9 0.1 4.2 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF948) WW PF00397.26 KXS21026.1 - 3.8e-09 36.5 6.5 6.1e-09 35.8 6.5 1.4 1 0 0 1 1 1 1 WW domain MFS_1 PF07690.16 KXS21027.1 - 7.1e-11 41.6 33.1 1.4e-10 40.7 33.1 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF2964 PF11177.8 KXS21027.1 - 1.9 8.7 6.0 0.25 11.6 1.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2964) Bax1-I PF01027.20 KXS21028.1 - 0.26 11.1 7.6 0.33 10.8 7.6 1.1 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 PsbN PF02468.15 KXS21028.1 - 0.48 10.3 4.1 7.8 6.4 0.3 2.6 2 0 0 2 2 2 0 Photosystem II reaction centre N protein (psbN) Lambda_CIII PF02061.16 KXS21028.1 - 0.99 9.5 3.0 27 4.9 1.6 2.3 2 0 0 2 2 2 0 Lambda Phage CIII Helicase_C PF00271.31 KXS21029.1 - 1.8e-18 66.9 0.0 4.7e-16 59.1 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KXS21029.1 - 3.6e-17 62.7 0.0 6.8e-17 61.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase HTH_40 PF14493.6 KXS21029.1 - 1.9e-08 34.6 0.0 3.8e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain RecQ_Zn_bind PF16124.5 KXS21029.1 - 2.9e-07 31.1 0.3 1e-06 29.4 0.3 2.0 1 0 0 1 1 1 1 RecQ zinc-binding RQC PF09382.10 KXS21029.1 - 6.4e-07 29.2 0.0 1.4e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 RQC domain HRDC PF00570.23 KXS21029.1 - 4.5e-06 26.6 0.0 9.4e-06 25.5 0.0 1.6 1 0 0 1 1 1 1 HRDC domain ResIII PF04851.15 KXS21029.1 - 0.021 14.8 0.0 0.038 14.0 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit cNMP_binding PF00027.29 KXS21030.1 - 7.6e-08 32.3 0.4 1e-06 28.7 0.0 2.8 3 0 0 3 3 3 1 Cyclic nucleotide-binding domain PNP_UDP_1 PF01048.20 KXS21030.1 - 0.0012 18.2 0.0 0.007 15.6 0.0 2.1 1 1 0 1 1 1 1 Phosphorylase superfamily F-box-like PF12937.7 KXS21031.1 - 0.00013 21.8 0.1 0.00033 20.5 0.1 1.8 1 1 0 1 1 1 1 F-box-like ADH_N PF08240.12 KXS21032.1 - 1.7e-27 95.4 0.7 3.3e-27 94.5 0.7 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXS21032.1 - 1.5e-17 63.8 0.4 2.9e-17 62.9 0.4 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TrkA_N PF02254.18 KXS21032.1 - 0.0089 16.3 0.4 0.014 15.7 0.4 1.3 1 0 0 1 1 1 1 TrkA-N domain CoA_binding PF02629.19 KXS21032.1 - 0.0094 16.6 0.6 0.14 12.9 0.6 2.6 2 1 1 3 3 3 1 CoA binding domain Oxidored_nitro PF00148.19 KXS21032.1 - 0.019 13.7 0.0 0.029 13.1 0.0 1.2 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase Methyltransf_18 PF12847.7 KXS21032.1 - 0.02 14.8 0.1 0.037 14.0 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase domain GFO_IDH_MocA PF01408.22 KXS21032.1 - 0.042 14.7 0.3 0.22 12.4 0.1 2.1 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold Lipase_3 PF01764.25 KXS21033.1 - 2.5e-09 37.1 0.0 5.3e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KXS21033.1 - 0.0026 18.4 4.1 0.017 15.7 0.1 3.0 3 0 0 3 3 3 1 Alpha/beta hydrolase family DUF2974 PF11187.8 KXS21033.1 - 0.028 14.0 0.0 4.5 6.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) GSHPx PF00255.19 KXS21034.1 - 1.7e-46 156.2 0.1 2.3e-46 155.8 0.1 1.2 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 KXS21034.1 - 5.2e-05 23.2 0.0 8.8e-05 22.4 0.0 1.7 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KXS21034.1 - 0.003 17.3 0.1 0.013 15.2 0.1 1.9 1 1 0 1 1 1 1 Redoxin Putative_PNPOx PF01243.20 KXS21036.1 - 3.7e-07 30.2 0.0 5.7e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase PPDK_N PF01326.19 KXS21037.1 - 1.7e-103 346.4 0.0 5.1e-103 344.8 0.0 1.7 2 0 0 2 2 2 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain PEP-utilizers_C PF02896.18 KXS21037.1 - 1e-47 162.7 0.0 1.9e-47 161.8 0.0 1.3 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PEP-utilizers PF00391.23 KXS21037.1 - 2.3e-25 88.1 0.3 5.8e-25 86.8 0.3 1.7 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain GARP PF16731.5 KXS21037.1 - 0.041 13.6 0.1 0.067 12.9 0.1 1.2 1 0 0 1 1 1 0 Glutamic acid/alanine-rich protein of Trypanosoma Methyltransf_12 PF08242.12 KXS21038.1 - 0.017 15.9 0.1 0.052 14.3 0.0 1.8 3 0 0 3 3 3 0 Methyltransferase domain RbsD_FucU PF05025.13 KXS21038.1 - 0.038 14.4 0.1 0.16 12.4 0.2 1.8 2 0 0 2 2 2 0 RbsD / FucU transport protein family PMP1_2 PF08114.11 KXS21038.1 - 0.045 13.5 0.5 0.094 12.5 0.5 1.4 1 0 0 1 1 1 0 ATPase proteolipid family Methyltransf_23 PF13489.6 KXS21038.1 - 0.056 13.3 0.0 0.093 12.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 KXS21039.1 - 0.18 12.6 0.0 0.49 11.2 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain GSHPx PF00255.19 KXS21040.1 - 8.5e-39 131.5 0.0 1.1e-38 131.1 0.0 1.2 1 0 0 1 1 1 1 Glutathione peroxidase Redoxin PF08534.10 KXS21040.1 - 5.7e-05 22.9 0.0 8.8e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 KXS21040.1 - 0.00046 20.1 0.0 0.00071 19.5 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Zn_clus PF00172.18 KXS21041.1 - 3e-07 30.4 7.1 5.1e-07 29.7 7.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXS21041.1 - 0.0014 17.7 0.8 0.0074 15.3 0.9 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain CBM_1 PF00734.18 KXS21042.1 - 2.2e-21 75.5 20.1 1e-10 41.4 2.9 2.8 2 0 0 2 2 2 2 Fungal cellulose binding domain Toxin_7 PF05980.12 KXS21042.1 - 0.016 15.5 5.9 0.016 15.5 5.9 3.1 3 0 0 3 3 3 0 Toxin 7 Hamartin PF04388.12 KXS21042.1 - 2.9 6.4 10.4 3 6.4 10.4 1.2 1 0 0 1 1 1 0 Hamartin protein MaoC_dehydrat_N PF13452.6 KXS21043.1 - 0.029 14.5 0.0 3 8.0 0.0 2.4 2 0 0 2 2 2 0 N-terminal half of MaoC dehydratase NAD_binding_8 PF13450.6 KXS21044.1 - 1.1e-06 28.7 0.0 9.1e-05 22.6 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXS21044.1 - 0.0002 20.7 0.0 0.032 13.5 0.0 3.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXS21044.1 - 0.0022 17.3 0.1 0.1 11.9 0.1 3.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 KXS21044.1 - 0.0023 18.0 0.2 0.16 12.0 0.0 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 KXS21044.1 - 0.015 14.5 0.4 0.063 12.5 0.2 2.0 2 0 0 2 2 2 0 FAD binding domain NAD_binding_9 PF13454.6 KXS21044.1 - 0.023 14.7 0.3 1.3 9.0 0.1 2.9 3 0 0 3 3 3 0 FAD-NAD(P)-binding 2-Hacid_dh_C PF02826.19 KXS21044.1 - 0.081 12.3 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pirin PF02678.16 KXS21045.1 - 4.3e-28 97.5 0.2 7.1e-28 96.7 0.2 1.3 1 0 0 1 1 1 1 Pirin Cupin_2 PF07883.11 KXS21045.1 - 5.3e-09 35.7 3.3 2.1e-08 33.8 1.0 2.4 2 0 0 2 2 2 1 Cupin domain Pirin_C_2 PF17954.1 KXS21045.1 - 0.0022 18.2 0.0 0.024 14.8 0.0 2.5 2 1 0 2 2 2 1 Quercetinase C-terminal cupin domain Cupin_3 PF05899.12 KXS21045.1 - 0.0029 17.3 0.3 0.2 11.4 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF861) AAA_22 PF13401.6 KXS21046.1 - 0.19 12.0 0.0 0.28 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain PAN_1 PF00024.26 KXS21047.1 - 3.6e-07 30.1 0.4 0.00015 21.6 0.1 2.2 2 0 0 2 2 2 2 PAN domain PAN_4 PF14295.6 KXS21047.1 - 0.00055 19.8 5.1 0.026 14.4 0.4 2.4 2 0 0 2 2 2 2 PAN domain Forkhead_N PF08430.12 KXS21048.1 - 2.7 8.6 15.9 4 8.0 15.9 1.3 1 0 0 1 1 1 0 Forkhead N-terminal region PAN_1 PF00024.26 KXS21050.1 - 0.00039 20.3 0.0 0.00039 20.3 0.0 3.0 3 1 0 3 3 3 1 PAN domain PAN_4 PF14295.6 KXS21050.1 - 0.091 12.7 3.4 1.3 9.0 0.4 2.4 2 0 0 2 2 2 0 PAN domain Endostatin PF06482.11 KXS21050.1 - 0.98 8.8 9.8 1.6 8.2 9.8 1.2 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Suf PF05843.14 KXS21050.1 - 6 6.7 9.6 9.8 6.1 9.6 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Oxidored_FMN PF00724.20 KXS21054.1 - 1.3e-71 241.6 0.0 1.7e-71 241.3 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family AP_endonuc_2 PF01261.24 KXS21054.1 - 0.029 13.8 0.0 0.083 12.3 0.0 1.8 2 1 0 2 2 2 0 Xylose isomerase-like TIM barrel SH3_9 PF14604.6 KXS21055.1 - 4.1e-07 29.7 0.1 1e-06 28.5 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXS21055.1 - 2.6e-05 23.7 0.0 5.4e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 SH3 domain MGC-24 PF05283.11 KXS21055.1 - 0.00097 19.6 1.2 0.0018 18.8 1.2 1.3 1 0 0 1 1 1 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin Herpes_gE PF02480.16 KXS21055.1 - 0.018 13.8 0.3 0.025 13.4 0.3 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E LRR_4 PF12799.7 KXS21055.1 - 0.045 14.2 6.2 0.21 12.1 2.8 2.4 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) stn_TNFRSF12A PF12191.8 KXS21055.1 - 0.053 13.7 0.1 0.16 12.2 0.1 1.8 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain LRR_8 PF13855.6 KXS21055.1 - 0.7 9.7 3.5 5 7.0 1.2 2.2 2 0 0 2 2 2 0 Leucine rich repeat ABC_membrane PF00664.23 KXS21056.1 - 1.7e-58 198.5 8.2 2.1e-40 139.1 5.9 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KXS21056.1 - 7.7e-12 45.9 0.0 1.3e-07 32.2 0.0 2.6 2 1 0 2 2 2 2 ABC transporter Cyclin_N PF00134.23 KXS21057.1 - 3.9e-14 52.5 0.0 8.9e-14 51.3 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain EF-hand_7 PF13499.6 KXS21058.1 - 2.3e-20 72.8 7.2 6.8e-12 45.7 1.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KXS21058.1 - 4e-14 51.0 11.5 0.0013 18.1 0.2 4.2 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 KXS21058.1 - 5.2e-10 38.4 9.9 0.0039 17.0 0.3 4.1 3 1 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 KXS21058.1 - 1e-05 25.2 7.0 0.93 9.4 0.1 4.1 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 KXS21058.1 - 0.00028 20.2 10.9 0.09 12.3 0.1 4.3 4 0 0 4 4 4 3 EF hand DUF4845 PF16137.5 KXS21058.1 - 0.0012 19.7 0.1 0.0026 18.6 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4845) SPARC_Ca_bdg PF10591.9 KXS21058.1 - 0.0088 16.3 0.4 0.084 13.2 0.1 2.3 2 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KXS21058.1 - 0.022 14.7 0.6 6.3 6.8 0.1 2.3 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand Mito_carr PF00153.27 KXS21059.1 - 1e-62 208.1 4.3 8.3e-20 70.5 0.1 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KXS21059.1 - 0.047 12.9 0.8 13 4.9 0.0 3.3 4 0 0 4 4 4 0 Gammaproteobacterial serine protease Mito_carr PF00153.27 KXS21060.1 - 1.2e-64 214.2 1.4 5e-21 74.4 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.32 KXS21060.1 - 1.2e-16 59.0 13.0 0.00045 19.6 0.1 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KXS21060.1 - 2e-16 60.2 12.0 6.6e-08 32.9 3.6 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KXS21060.1 - 1.4e-13 49.5 10.2 0.00049 19.8 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KXS21060.1 - 8.4e-09 34.5 12.3 0.0039 16.6 0.1 4.5 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 KXS21060.1 - 8.4e-07 28.8 12.5 0.085 12.7 0.0 4.5 3 1 1 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KXS21060.1 - 0.00096 19.5 0.2 0.21 11.9 0.0 2.4 2 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region RE_Eco47II PF09553.10 KXS21060.1 - 0.18 11.3 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 Eco47II restriction endonuclease DDE_3 PF13358.6 KXS21062.1 - 9.9e-17 61.1 0.0 1.2e-16 60.8 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease CLTH PF10607.9 KXS21064.1 - 8.3e-29 100.4 0.0 1.2e-28 99.8 0.0 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.28 KXS21064.1 - 7e-25 87.5 0.5 1.3e-24 86.6 0.5 1.5 1 0 0 1 1 1 1 SPRY domain LisH PF08513.11 KXS21064.1 - 1.4e-05 24.9 0.1 3.1e-05 23.8 0.1 1.6 1 0 0 1 1 1 1 LisH PI3_PI4_kinase PF00454.27 KXS21067.1 - 1.7e-56 191.8 0.1 3.9e-56 190.7 0.1 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 KXS21067.1 - 8.1e-37 127.2 7.0 2.5e-36 125.6 7.0 1.9 1 0 0 1 1 1 1 FAT domain FATC PF02260.20 KXS21067.1 - 6.9e-15 54.6 0.1 1.4e-14 53.6 0.1 1.6 1 0 0 1 1 1 1 FATC domain ELL PF10390.9 KXS21068.1 - 3e-07 30.2 0.1 3e-07 30.2 0.1 2.5 2 1 0 2 2 2 1 RNA polymerase II elongation factor ELL DprA_WH PF17782.1 KXS21068.1 - 0.00094 19.2 0.3 0.0032 17.6 0.3 1.9 1 0 0 1 1 1 1 DprA winged helix domain Met_10 PF02475.16 KXS21069.1 - 3.5e-61 206.5 0.0 3e-44 151.2 0.0 2.1 1 1 1 2 2 2 2 Met-10+ like-protein TRM PF02005.16 KXS21069.1 - 0.008 15.4 0.0 0.013 14.7 0.0 1.2 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase DUF2956 PF11169.8 KXS21069.1 - 0.61 10.3 3.4 1.1 9.5 3.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) NDK PF00334.19 KXS21070.1 - 9.3e-116 381.8 0.0 1.2e-39 135.4 0.0 3.4 3 0 0 3 3 3 3 Nucleoside diphosphate kinase Thioredoxin PF00085.20 KXS21070.1 - 1.7e-05 24.8 0.0 3.2e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin DUF3567 PF12091.8 KXS21070.1 - 0.03 14.4 0.3 0.22 11.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3567) DDOST_48kD PF03345.14 KXS21071.1 - 4.5e-125 417.7 2.4 5.2e-125 417.6 2.4 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta Neuraminidase PF18413.1 KXS21071.1 - 0.086 12.5 0.1 0.14 11.8 0.1 1.3 1 0 0 1 1 1 0 Neuraminidase-like domain Pkinase PF00069.25 KXS21072.1 - 4.3e-60 203.3 0.0 5.5e-60 203.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS21072.1 - 8.1e-37 126.9 0.0 1.1e-36 126.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXS21072.1 - 9.2e-07 28.4 0.0 2.4e-06 27.1 0.0 1.7 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 KXS21072.1 - 0.073 13.0 0.0 0.34 10.8 0.0 1.9 1 1 0 2 2 2 0 Phosphotransferase enzyme family PIP49_C PF12260.8 KXS21072.1 - 0.19 11.4 0.0 0.37 10.4 0.0 1.4 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 Hemerythrin PF01814.23 KXS21073.1 - 2e-11 44.6 1.2 4.7e-11 43.4 0.7 1.7 2 0 0 2 2 2 1 Hemerythrin HHE cation binding domain Aldose_epim PF01263.20 KXS21074.1 - 1.6e-47 162.2 0.5 2.2e-47 161.8 0.5 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase UMPH-1 PF05822.12 KXS21075.1 - 6.8e-21 74.9 0.0 7.8e-21 74.7 0.0 1.0 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) DAO PF01266.24 KXS21076.1 - 3e-54 185.0 0.5 3.7e-54 184.6 0.5 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXS21076.1 - 0.00049 20.3 0.1 0.0012 19.1 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GMC_oxred_N PF00732.19 KXS21076.1 - 0.018 14.4 0.0 0.035 13.5 0.0 1.4 1 0 0 1 1 1 0 GMC oxidoreductase Pyr_redox PF00070.27 KXS21076.1 - 0.024 15.2 0.1 0.054 14.0 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXS21076.1 - 0.064 12.5 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXS21076.1 - 0.096 11.9 0.1 0.24 10.6 0.0 1.6 2 0 0 2 2 2 0 Thi4 family NAD_binding_9 PF13454.6 KXS21076.1 - 0.16 11.9 0.1 0.27 11.2 0.1 1.3 1 0 0 1 1 1 0 FAD-NAD(P)-binding ApbA PF02558.16 KXS21076.1 - 0.18 11.4 0.0 0.28 10.8 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.19 KXS21076.1 - 0.25 10.5 0.8 0.37 10.0 0.2 1.5 2 0 0 2 2 2 0 FAD binding domain Stc1 PF12898.7 KXS21077.1 - 0.0013 19.3 8.7 0.0033 17.9 8.8 1.6 1 1 0 1 1 1 1 Stc1 domain zinc_ribbon_6 PF14599.6 KXS21077.1 - 1.2 9.3 8.0 0.14 12.2 1.2 2.6 2 1 1 3 3 3 0 Zinc-ribbon Cytochrom_c3_2 PF14537.6 KXS21077.1 - 1.3 9.6 8.8 12 6.5 4.5 2.8 1 1 1 2 2 2 0 Cytochrome c3 E1-E2_ATPase PF00122.20 KXS21078.1 - 1.1e-44 152.1 4.0 1.1e-44 152.1 4.0 2.9 2 1 1 3 3 3 1 E1-E2 ATPase Cation_ATPase_N PF00690.26 KXS21078.1 - 5.1e-13 48.5 0.6 3.4e-12 45.9 0.0 2.3 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 KXS21078.1 - 0.0015 18.6 0.0 0.0031 17.6 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KXS21078.1 - 0.0053 17.1 0.0 0.018 15.3 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KXS21079.1 - 1.1e-45 155.4 3.9 1.1e-45 155.4 3.9 2.8 2 1 1 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 KXS21079.1 - 1.5e-18 67.8 0.1 4.4e-18 66.3 0.1 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KXS21079.1 - 6.3e-13 48.2 0.3 3.2e-12 46.0 0.0 2.2 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 KXS21079.1 - 0.0011 19.0 0.0 0.0024 17.9 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KXS21079.1 - 0.0069 16.2 0.1 0.014 15.2 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase 2OG-FeII_Oxy_3 PF13640.6 KXS21080.1 - 2.3e-13 50.8 0.2 4e-13 50.1 0.2 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Glyco_transf_20 PF00982.21 KXS21082.1 - 4.1e-188 625.9 0.0 6.2e-188 625.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 KXS21082.1 - 5e-45 153.4 0.1 4.2e-27 94.8 0.0 2.5 2 0 0 2 2 2 2 Trehalose-phosphatase Hydrolase_3 PF08282.12 KXS21082.1 - 2.4e-08 34.1 0.0 0.0039 17.0 0.0 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Glyco_trans_1_4 PF13692.6 KXS21082.1 - 0.0019 18.6 0.0 0.0072 16.8 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 KXS21082.1 - 0.037 13.7 0.1 0.098 12.3 0.1 1.6 1 0 0 1 1 1 0 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 KXS21082.1 - 0.042 13.4 0.2 0.34 10.4 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferases group 1 UvrB PF12344.8 KXS21082.1 - 0.092 12.6 1.2 0.18 11.7 1.2 1.5 1 0 0 1 1 1 0 Ultra-violet resistance protein B UMPH-1 PF05822.12 KXS21083.1 - 3.3e-61 207.0 0.0 3.6e-61 206.8 0.0 1.0 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) Aldose_epim PF01263.20 KXS21084.1 - 1.6e-47 162.2 0.5 2.2e-47 161.8 0.5 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase Adaptin_N PF01602.20 KXS21086.1 - 8.1e-135 450.3 13.3 9.6e-135 450.1 13.3 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KXS21086.1 - 3.3e-57 193.0 9.6 6.7e-56 188.8 2.0 3.1 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KXS21086.1 - 5.6e-14 52.3 4.1 5.3e-07 29.9 0.0 5.2 2 2 4 6 6 6 5 HEAT repeats HEAT PF02985.22 KXS21086.1 - 6.8e-08 32.1 3.2 0.17 12.2 0.1 6.1 6 0 0 6 6 6 2 HEAT repeat Cnd3 PF12719.7 KXS21086.1 - 1.8e-05 24.1 0.6 0.00086 18.6 0.0 2.6 2 1 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain FANCI_S3 PF14677.6 KXS21086.1 - 0.00028 20.7 0.1 0.00063 19.5 0.1 1.7 1 0 0 1 1 1 1 FANCI solenoid 3 CLASP_N PF12348.8 KXS21086.1 - 0.00031 20.4 0.1 0.43 10.1 0.0 3.1 2 1 0 2 2 2 2 CLASP N terminal Arm PF00514.23 KXS21086.1 - 0.00059 19.8 1.1 20 5.4 0.0 4.8 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat RTP1_C1 PF10363.9 KXS21086.1 - 0.00064 19.9 7.1 1.2 9.3 0.9 4.5 4 1 0 4 4 4 2 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_UF PF18817.1 KXS21086.1 - 0.0053 17.0 1.0 10 6.5 0.0 3.9 3 0 0 3 3 3 1 Repeat of uncharacterized protein PH0542 HEAT_EZ PF13513.6 KXS21086.1 - 0.0076 16.7 0.3 20 5.8 0.0 4.5 4 1 1 5 5 5 0 HEAT-like repeat Sec7_N PF12783.7 KXS21086.1 - 0.042 13.8 1.0 0.2 11.6 0.3 2.5 1 1 1 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal RasGEF_N_2 PF14663.6 KXS21086.1 - 0.14 12.5 2.1 4.2 7.8 0.1 3.1 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain MaoC_dehydratas PF01575.19 KXS21087.1 - 2.9e-35 120.5 0.0 1.2e-34 118.6 0.0 1.8 2 0 0 2 2 2 1 MaoC like domain MaoC_dehydrat_N PF13452.6 KXS21087.1 - 3.7e-08 33.6 0.0 1.6e-05 25.1 0.0 2.4 2 1 0 2 2 2 2 N-terminal half of MaoC dehydratase His_Phos_1 PF00300.22 KXS21088.1 - 5.2e-58 195.9 0.0 6.5e-58 195.6 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) ABC_tran PF00005.27 KXS21090.1 - 2e-46 157.9 0.1 1.1e-22 81.0 0.0 2.5 3 0 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 KXS21090.1 - 1.4e-21 76.3 1.9 2.4e-21 75.5 1.9 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KXS21090.1 - 6.2e-16 59.1 0.0 0.0015 18.4 0.0 4.4 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KXS21090.1 - 6.2e-10 38.9 0.0 0.021 14.3 0.0 3.9 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KXS21090.1 - 3.6e-08 34.2 6.2 0.0027 18.2 0.1 3.4 3 0 0 3 3 3 2 AAA domain AAA_30 PF13604.6 KXS21090.1 - 9.1e-08 32.0 0.3 0.00049 19.9 0.0 3.2 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KXS21090.1 - 4.5e-07 30.4 0.4 0.037 14.4 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_15 PF13175.6 KXS21090.1 - 4.9e-06 26.5 1.8 0.048 13.4 0.1 2.7 3 0 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 KXS21090.1 - 8.7e-06 26.0 0.7 0.21 11.8 0.0 3.0 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KXS21090.1 - 8.9e-06 25.4 1.0 0.051 13.3 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KXS21090.1 - 1.1e-05 25.5 0.2 0.099 12.5 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA PF00004.29 KXS21090.1 - 1.3e-05 25.7 0.1 0.3 11.5 0.0 2.9 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 KXS21090.1 - 2.7e-05 23.5 0.0 0.13 11.4 0.0 2.3 2 0 0 2 2 2 2 NB-ARC domain NACHT PF05729.12 KXS21090.1 - 5.3e-05 23.2 0.6 0.38 10.7 0.0 2.8 3 0 0 3 3 3 2 NACHT domain PduV-EutP PF10662.9 KXS21090.1 - 5.5e-05 22.9 0.0 0.27 11.0 0.0 2.3 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.6 KXS21090.1 - 7.5e-05 22.5 0.0 0.46 10.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 KXS21090.1 - 0.00022 21.5 0.1 0.56 10.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 KXS21090.1 - 0.0003 20.8 0.1 0.83 9.8 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase NTPase_1 PF03266.15 KXS21090.1 - 0.00041 20.3 0.6 0.77 9.7 0.1 2.7 2 0 0 2 2 2 2 NTPase cobW PF02492.19 KXS21090.1 - 0.0011 18.7 0.5 0.98 9.0 0.1 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain Roc PF08477.13 KXS21090.1 - 0.0019 18.4 0.3 1.6 8.9 0.0 2.8 3 0 0 3 3 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_14 PF13173.6 KXS21090.1 - 0.0028 17.7 0.0 4.4 7.4 0.0 2.9 3 0 0 3 3 2 0 AAA domain Seryl_tRNA_N PF02403.22 KXS21090.1 - 0.0044 17.2 1.1 0.0087 16.3 0.1 1.9 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain AAA_19 PF13245.6 KXS21090.1 - 0.0068 16.7 1.3 7.3 6.9 0.0 3.1 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KXS21090.1 - 0.0091 16.5 0.0 1.8 9.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 KXS21090.1 - 0.018 15.0 0.7 7 6.5 0.0 2.8 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea AAA_27 PF13514.6 KXS21090.1 - 0.018 14.6 0.8 1.3 8.6 0.0 2.6 2 1 0 2 2 2 0 AAA domain DUF3584 PF12128.8 KXS21090.1 - 0.019 12.5 0.0 0.019 12.5 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3584) TsaE PF02367.17 KXS21090.1 - 0.021 14.8 0.1 5.3 7.0 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MobB PF03205.14 KXS21090.1 - 0.023 14.6 0.2 9.1 6.2 0.1 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B IstB_IS21 PF01695.17 KXS21090.1 - 0.025 14.3 0.1 3 7.5 0.0 2.7 2 0 0 2 2 2 0 IstB-like ATP binding protein Bac_DnaA PF00308.18 KXS21090.1 - 0.027 14.3 0.1 0.63 9.8 0.0 2.3 2 0 0 2 2 2 0 Bacterial dnaA protein MeaB PF03308.16 KXS21090.1 - 0.031 13.2 0.1 1.2 8.0 0.0 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RNA_helicase PF00910.22 KXS21090.1 - 0.046 14.1 0.0 12 6.3 0.0 2.4 2 0 0 2 2 2 0 RNA helicase AAA_33 PF13671.6 KXS21090.1 - 0.052 13.7 6.4 1.4 9.1 0.0 2.8 3 1 0 3 3 2 0 AAA domain DLIC PF05783.11 KXS21090.1 - 0.065 12.1 0.0 2.8 6.7 0.0 2.1 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) Zeta_toxin PF06414.12 KXS21090.1 - 0.11 11.8 0.0 1.2 8.4 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin Septin PF00735.18 KXS21090.1 - 0.13 11.5 0.0 10 5.3 0.0 2.2 2 0 0 2 2 2 0 Septin KAP_NTPase PF07693.14 KXS21090.1 - 0.14 11.4 0.1 11 5.1 0.0 2.3 2 1 0 2 2 2 0 KAP family P-loop domain AAA_13 PF13166.6 KXS21090.1 - 0.14 10.8 1.0 3.8 6.0 0.0 2.7 3 0 0 3 3 3 0 AAA domain RuvB_N PF05496.12 KXS21090.1 - 0.14 11.9 0.5 5 6.9 0.0 2.7 3 0 0 3 3 2 0 Holliday junction DNA helicase RuvB P-loop domain RGS_DHEX PF18148.1 KXS21090.1 - 0.15 12.2 1.0 0.3 11.2 1.0 1.4 1 0 0 1 1 1 0 Regulator of G-protein signalling DHEX domain SbcCD_C PF13558.6 KXS21090.1 - 0.15 12.3 0.8 7.4 6.9 0.1 3.6 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_7 PF12775.7 KXS21090.1 - 0.16 11.5 0.1 8.5 5.8 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region SRP54 PF00448.22 KXS21090.1 - 0.18 11.4 5.7 2.8 7.5 0.1 3.0 2 1 0 2 2 2 0 SRP54-type protein, GTPase domain Dynamin_N PF00350.23 KXS21090.1 - 0.2 11.7 0.1 7.4 6.6 0.0 2.9 3 0 0 3 3 3 0 Dynamin family ABC_ATPase PF09818.9 KXS21090.1 - 0.3 9.9 2.4 44 2.7 0.3 3.5 3 1 0 4 4 4 0 Predicted ATPase of the ABC class NAD_binding_10 PF13460.6 KXS21091.1 - 5.9e-09 36.1 0.1 9.1e-09 35.5 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KXS21091.1 - 1.2e-08 34.8 0.0 2.1e-08 34.0 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KXS21091.1 - 0.0017 18.0 0.0 0.09 12.3 0.0 2.1 2 0 0 2 2 2 1 NmrA-like family GDP_Man_Dehyd PF16363.5 KXS21091.1 - 0.0065 15.9 0.0 0.17 11.3 0.0 2.0 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KXS21091.1 - 0.05 12.6 0.0 0.17 10.9 0.0 2.0 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Forkhead PF00250.18 KXS21092.1 - 2.7e-36 123.7 0.3 4e-36 123.1 0.3 1.3 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 KXS21092.1 - 6.7e-05 23.2 0.0 0.00011 22.4 0.0 1.4 1 0 0 1 1 1 1 FHA domain Linker_histone PF00538.19 KXS21092.1 - 0.017 15.4 0.0 0.036 14.4 0.0 1.5 1 0 0 1 1 1 0 linker histone H1 and H5 family Peptidase_M16 PF00675.20 KXS21093.1 - 2e-50 170.6 0.3 3.2e-50 170.0 0.3 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KXS21093.1 - 5e-38 130.9 0.0 2.6e-37 128.6 0.0 2.0 2 0 0 2 2 2 1 Peptidase M16 inactive domain Polysacc_deac_1 PF01522.21 KXS21095.1 - 2.2e-31 108.3 0.0 6.1e-31 106.9 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 KXS21095.1 - 0.0056 15.9 0.0 0.0067 15.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 MTBP_mid PF14919.6 KXS21095.1 - 0.067 12.4 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 MDM2-binding F-box-like PF12937.7 KXS21096.1 - 0.016 15.1 0.1 0.047 13.6 0.1 1.7 1 0 0 1 1 1 0 F-box-like Syntaxin PF00804.25 KXS21097.1 - 4.3e-42 144.1 15.7 4.3e-42 144.1 15.7 1.9 1 1 1 2 2 2 1 Syntaxin SNARE PF05739.19 KXS21097.1 - 5.3e-17 61.5 1.8 5.3e-17 61.5 1.8 2.2 2 0 0 2 2 2 1 SNARE domain Syntaxin_2 PF14523.6 KXS21097.1 - 8.2e-05 22.9 4.2 8.2e-05 22.9 4.2 2.9 2 1 0 2 2 2 1 Syntaxin-like protein Prominin PF05478.11 KXS21097.1 - 0.0083 14.1 14.3 0.026 12.5 14.4 1.7 1 1 0 1 1 1 1 Prominin DUF3169 PF11368.8 KXS21097.1 - 0.016 14.7 1.2 0.027 14.0 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) Vac7 PF12751.7 KXS21097.1 - 0.029 13.8 4.2 0.054 12.9 4.2 1.4 1 1 0 1 1 1 0 Vacuolar segregation subunit 7 LMBR1 PF04791.16 KXS21097.1 - 0.035 13.0 3.9 0.044 12.7 3.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Insulin_TMD PF17870.1 KXS21097.1 - 0.45 10.6 3.5 0.83 9.8 3.5 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment ABC2_membrane_3 PF12698.7 KXS21097.1 - 0.72 8.9 2.6 0.67 9.0 1.6 1.4 1 1 0 1 1 1 0 ABC-2 family transporter protein T2SSF PF00482.23 KXS21097.1 - 1.6 8.7 6.6 7.6 6.5 0.1 3.2 2 1 0 3 3 3 0 Type II secretion system (T2SS), protein F DUF2203 PF09969.9 KXS21097.1 - 3.7 8.3 14.4 7.6 7.3 4.0 2.7 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) DUF2207 PF09972.9 KXS21097.1 - 4.2 6.0 7.3 26 3.4 7.4 2.0 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF2116 PF09889.9 KXS21097.1 - 4.7 7.3 7.2 0.33 11.0 1.1 2.1 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) NUDE_C PF04880.13 KXS21098.1 - 4.7e-14 53.2 3.6 4.7e-14 53.2 3.6 3.1 2 1 1 3 3 3 1 NUDE protein, C-terminal conserved region TPR_MLP1_2 PF07926.12 KXS21098.1 - 0.0048 17.0 6.0 0.0048 17.0 6.0 3.6 3 1 0 4 4 4 1 TPR/MLP1/MLP2-like protein CALCOCO1 PF07888.11 KXS21098.1 - 0.02 13.8 23.5 0.032 13.1 23.5 1.3 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF3584 PF12128.8 KXS21098.1 - 0.083 10.4 19.5 0.13 9.8 19.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) ZapB PF06005.12 KXS21098.1 - 0.12 12.8 27.4 1.2 9.6 7.0 3.6 2 1 1 3 3 3 0 Cell division protein ZapB KASH_CCD PF14662.6 KXS21098.1 - 0.23 11.2 25.4 0.25 11.1 23.3 1.9 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH TMF_TATA_bd PF12325.8 KXS21098.1 - 1.3 9.3 24.0 27 5.0 22.4 3.0 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Lectin_N PF03954.14 KXS21098.1 - 1.4 8.6 11.4 1.2 8.9 3.8 2.4 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain V_ATPase_I PF01496.19 KXS21098.1 - 2 6.3 12.6 1.3 6.9 10.2 1.6 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family DUF1664 PF07889.12 KXS21098.1 - 2.4 8.2 17.5 0.18 11.8 3.5 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Spc7 PF08317.11 KXS21098.1 - 3.2 6.5 27.4 2.9 6.7 17.5 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein Fez1 PF06818.15 KXS21098.1 - 4.2 7.8 24.6 4.1 7.8 8.8 2.3 1 1 1 2 2 2 0 Fez1 DUF4407 PF14362.6 KXS21098.1 - 4.4 6.6 16.5 15 4.8 15.8 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) Syntaxin_2 PF14523.6 KXS21098.1 - 8.1 6.9 15.4 16 5.9 0.0 3.6 2 1 1 3 3 3 0 Syntaxin-like protein DUF812 PF05667.11 KXS21098.1 - 8.5 5.1 19.8 12 4.6 19.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Fzo_mitofusin PF04799.13 KXS21098.1 - 9.3 5.8 14.0 2.7 7.5 3.8 2.5 2 0 0 2 2 2 0 fzo-like conserved region Peptidase_M28 PF04389.17 KXS21099.1 - 1.8e-40 138.7 0.1 2.6e-40 138.3 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M28 Cytochrom_C1 PF02167.15 KXS21100.1 - 6.6e-96 320.3 0.0 8.5e-96 319.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 KXS21100.1 - 0.0009 19.5 0.0 0.002 18.4 0.0 1.6 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 KXS21100.1 - 0.0023 19.1 0.1 0.0061 17.7 0.1 1.8 1 1 0 1 1 1 1 Cytochrome c Arylesterase PF01731.20 KXS21101.1 - 6.4e-09 35.9 0.0 0.00014 22.0 0.0 2.9 2 1 1 3 3 3 2 Arylesterase SGL PF08450.12 KXS21101.1 - 1.7e-05 24.6 0.0 0.00015 21.5 0.0 2.2 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 KXS21101.1 - 0.093 12.9 0.0 0.25 11.5 0.0 1.7 1 0 0 1 1 1 0 Strictosidine synthase NKAP PF15692.5 KXS21102.1 - 0.34 11.6 2.3 0.78 10.5 2.3 1.7 1 1 0 1 1 1 0 NF-kappa-B-activating protein AKAP95 PF04988.12 KXS21103.1 - 0.044 14.0 0.2 0.067 13.4 0.2 1.2 1 0 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_4 PF13894.6 KXS21103.1 - 5.6 8.1 10.2 28 5.9 0.6 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KXS21103.1 - 8.5 7.0 12.1 6.3 7.4 0.3 3.0 3 0 0 3 3 3 0 Zinc-finger double domain TPP_enzyme_N PF02776.18 KXS21104.1 - 0.017 14.7 0.4 0.044 13.4 0.4 1.8 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain Sina PF03145.16 KXS21105.1 - 3e-05 24.1 0.9 4.9e-05 23.4 0.9 1.3 1 0 0 1 1 1 1 Seven in absentia protein family CIA30 PF08547.12 KXS21107.1 - 3.9e-32 111.5 0.0 4.6e-32 111.2 0.0 1.0 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) CIA30 PF08547.12 KXS21108.1 - 1.7e-36 125.7 0.0 1.9e-36 125.5 0.0 1.0 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) Pyridoxal_deC PF00282.19 KXS21109.1 - 4e-17 62.0 0.0 2e-16 59.7 0.0 1.9 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 KXS21109.1 - 3.4e-08 32.9 0.0 2.7e-07 29.9 0.0 2.2 2 1 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KXS21109.1 - 1.1e-05 24.9 0.0 1.9e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family SH3_9 PF14604.6 KXS21110.1 - 1.5e-05 24.7 0.0 3e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXS21110.1 - 0.0013 18.3 0.0 0.0022 17.6 0.0 1.4 1 0 0 1 1 1 1 SH3 domain ABC_tran PF00005.27 KXS21111.1 - 1.6e-25 90.2 0.0 3.2e-25 89.2 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 KXS21111.1 - 1.9e-18 66.6 21.0 1.9e-18 66.6 21.0 1.7 2 0 0 2 2 2 1 ABC-2 type transporter AAA_21 PF13304.6 KXS21111.1 - 1.3e-05 25.1 0.0 0.088 12.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KXS21111.1 - 0.00054 19.9 0.1 0.0011 18.9 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase T2SSE PF00437.20 KXS21111.1 - 0.0011 18.1 0.1 0.0018 17.4 0.1 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_28 PF13521.6 KXS21111.1 - 0.011 15.9 0.1 0.03 14.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KXS21111.1 - 0.024 14.9 0.0 0.065 13.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KXS21111.1 - 0.026 14.3 0.7 0.063 13.0 0.7 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 KXS21111.1 - 0.03 14.7 0.0 0.056 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 KXS21111.1 - 0.034 13.7 0.0 0.083 12.4 0.0 1.6 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KXS21111.1 - 0.041 13.8 0.1 0.086 12.8 0.1 1.5 1 0 0 1 1 1 0 NACHT domain MMR_HSR1 PF01926.23 KXS21111.1 - 0.13 12.4 0.1 0.37 10.9 0.0 1.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase Pox_A32 PF04665.12 KXS21111.1 - 0.23 10.9 0.2 0.49 9.8 0.2 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein ABC2_membrane_3 PF12698.7 KXS21111.1 - 1.8 7.6 21.7 3.4 6.7 21.6 1.5 1 1 0 1 1 1 0 ABC-2 family transporter protein PDR_CDR PF06422.12 KXS21111.1 - 9.9 6.1 5.9 1.3 9.0 0.9 2.2 2 0 0 2 2 2 0 CDR ABC transporter Ribosomal_L34 PF00468.17 KXS21112.1 - 1.2e-17 63.5 9.5 2e-17 62.9 9.5 1.3 1 0 0 1 1 1 1 Ribosomal protein L34 RasGEF PF00617.19 KXS21113.1 - 1.5e-41 142.5 0.1 2.4e-41 141.8 0.1 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KXS21113.1 - 4.2e-24 84.8 0.2 1.2e-23 83.3 0.1 1.9 2 0 0 2 2 2 1 RasGEF N-terminal motif Glyco_hydro_31 PF01055.26 KXS21114.1 - 4.6e-145 484.2 4.7 6e-145 483.8 4.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 KXS21114.1 - 8.2e-16 58.1 0.1 5.5e-14 52.2 0.0 2.7 2 0 0 2 2 2 1 Galactose mutarotase-like DUF5110 PF17137.4 KXS21114.1 - 4.3e-05 23.7 0.1 0.00012 22.3 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF5110) EB PF01683.18 KXS21115.1 - 0.0087 16.3 6.1 0.15 12.4 5.0 2.2 1 1 1 2 2 2 2 EB module Dickkopf_N PF04706.12 KXS21115.1 - 0.077 13.5 9.4 0.2 12.1 9.4 1.7 1 1 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region Squash PF00299.18 KXS21115.1 - 0.64 10.1 2.8 3.9 7.6 0.4 2.4 2 0 0 2 2 2 0 Squash family serine protease inhibitor GatB_N PF02934.15 KXS21116.1 - 9.7e-97 323.6 0.0 1.2e-96 323.3 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 KXS21116.1 - 7.1e-20 71.4 0.0 1.1e-19 70.8 0.0 1.3 1 0 0 1 1 1 1 GatB domain ACC_central PF08326.12 KXS21117.1 - 4.7e-177 590.5 0.0 6.2e-177 590.1 0.0 1.2 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.22 KXS21117.1 - 3.4e-160 533.9 0.0 4.5e-160 533.5 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 KXS21117.1 - 1.1e-55 188.4 0.1 2.1e-55 187.5 0.1 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 KXS21117.1 - 1.7e-29 102.5 0.2 3.6e-29 101.5 0.2 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KXS21117.1 - 4e-22 78.3 0.0 9.9e-22 77.1 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 KXS21117.1 - 2.5e-11 43.2 0.0 7.2e-11 41.8 0.0 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_3 PF02655.14 KXS21117.1 - 0.00022 21.3 0.0 0.00057 20.0 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 KXS21117.1 - 0.00034 20.2 0.0 0.00076 19.1 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KXS21117.1 - 0.016 14.8 0.1 0.035 13.7 0.1 1.5 1 0 0 1 1 1 0 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 KXS21117.1 - 0.044 13.6 0.0 1.9 8.4 0.0 2.8 2 0 0 2 2 2 0 Biotin-lipoyl like GxGYxYP_N PF16216.5 KXS21117.1 - 0.073 13.2 0.1 0.17 12.1 0.1 1.6 1 0 0 1 1 1 0 GxGYxY sequence motif in domain of unknown function N-terminal Pyrid_ox_like PF16242.5 KXS21118.1 - 7.5e-31 106.7 0.0 1.1e-30 106.2 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase like Putative_PNPOx PF01243.20 KXS21118.1 - 2.9e-09 37.0 0.0 1e-08 35.2 0.0 1.8 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Hva1_TUDOR PF11160.8 KXS21119.1 - 5.7e-08 32.8 2.8 0.0056 16.8 0.8 2.4 1 1 1 2 2 2 2 Hypervirulence associated proteins TUDOR domain HAS-barrel PF09378.10 KXS21119.1 - 0.013 15.6 0.1 0.015 15.4 0.1 1.4 1 1 0 1 1 1 0 HAS barrel domain VASt PF16016.5 KXS21120.1 - 1.1e-17 64.9 0.0 1.7e-17 64.2 0.0 1.3 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 KXS21120.1 - 4.8e-12 45.8 0.1 8.2e-12 45.0 0.1 1.3 1 0 0 1 1 1 1 GRAM domain FMN_dh PF01070.18 KXS21121.1 - 5.9e-120 400.5 0.0 6.7e-120 400.3 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 KXS21121.1 - 3.5e-08 32.9 0.4 6e-07 28.8 0.2 2.5 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 KXS21121.1 - 1.7e-05 24.2 0.1 2.7e-05 23.5 0.1 1.4 1 1 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.21 KXS21121.1 - 0.00011 21.8 0.0 0.0012 18.3 0.0 2.4 2 1 1 3 3 3 1 Histidine biosynthesis protein NMO PF03060.15 KXS21121.1 - 0.00013 21.5 0.1 0.00021 20.8 0.1 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase DHO_dh PF01180.21 KXS21121.1 - 0.0005 19.4 0.3 0.0066 15.7 0.0 2.4 2 1 1 3 3 3 1 Dihydroorotate dehydrogenase ThiG PF05690.14 KXS21121.1 - 0.00053 19.4 0.5 0.12 11.6 0.0 2.7 2 1 0 3 3 3 2 Thiazole biosynthesis protein ThiG TMP-TENI PF02581.17 KXS21121.1 - 0.12 11.7 0.0 2.3 7.5 0.0 2.4 2 1 0 2 2 2 0 Thiamine monophosphate synthase G3P_antiterm PF04309.12 KXS21121.1 - 0.15 11.5 0.0 12 5.2 0.0 2.4 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator EST1 PF10374.9 KXS21122.1 - 7.1e-14 52.6 0.0 1.3e-13 51.8 0.0 1.4 1 0 0 1 1 1 1 Telomerase activating protein Est1 EST1_DNA_bind PF10373.9 KXS21122.1 - 0.013 15.0 0.0 0.021 14.3 0.0 1.3 1 0 0 1 1 1 0 Est1 DNA/RNA binding domain LRR_6 PF13516.6 KXS21123.1 - 6.9e-08 32.0 9.3 0.12 12.5 0.0 5.9 7 0 0 7 7 7 3 Leucine Rich repeat LRR_4 PF12799.7 KXS21123.1 - 2e-06 28.1 5.1 0.0064 16.9 0.2 4.7 3 2 1 4 4 4 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXS21123.1 - 9.7e-05 22.1 1.9 0.052 13.3 0.1 4.0 2 1 1 3 3 3 1 Leucine rich repeat LRR_1 PF00560.33 KXS21123.1 - 0.32 11.7 4.1 1.7e+02 3.4 0.0 4.8 5 1 0 5 5 5 0 Leucine Rich Repeat ABC_tran PF00005.27 KXS21124.1 - 1.2e-50 171.6 0.5 2e-24 86.6 0.0 2.9 3 0 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 KXS21124.1 - 9.7e-21 74.8 5.7 1.2e-06 28.6 0.0 4.2 2 2 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran_Xtn PF12848.7 KXS21124.1 - 1.2e-13 50.9 6.5 2.2e-13 50.0 6.5 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KXS21124.1 - 7.5e-09 35.3 0.6 0.14 11.5 0.0 4.2 2 2 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KXS21124.1 - 6.1e-08 32.3 1.2 0.0022 17.7 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KXS21124.1 - 8.7e-06 25.8 2.0 0.034 14.2 0.0 3.4 4 0 0 4 4 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KXS21124.1 - 1.1e-05 25.4 6.5 0.0031 17.4 0.0 3.3 3 0 0 3 3 3 2 RsgA GTPase AAA_24 PF13479.6 KXS21124.1 - 1.1e-05 25.3 1.1 0.54 9.9 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_23 PF13476.6 KXS21124.1 - 1.2e-05 25.9 11.3 0.038 14.5 0.0 3.9 4 0 0 4 4 4 2 AAA domain AAA_22 PF13401.6 KXS21124.1 - 1.6e-05 25.2 0.0 0.068 13.4 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_15 PF13175.6 KXS21124.1 - 2.9e-05 23.9 0.2 0.1 12.3 0.0 4.0 4 0 0 4 4 4 1 AAA ATPase domain AAA_18 PF13238.6 KXS21124.1 - 0.00016 22.3 0.0 0.78 10.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 KXS21124.1 - 0.00019 21.7 0.3 1.3 9.3 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.6 KXS21124.1 - 0.00028 21.3 0.3 1.3 9.3 0.0 2.8 2 1 0 2 2 2 2 AAA ATPase domain AAA_14 PF13173.6 KXS21124.1 - 0.00029 20.9 0.0 0.86 9.6 0.0 3.2 3 0 0 3 3 2 2 AAA domain AAA_33 PF13671.6 KXS21124.1 - 0.00046 20.4 0.1 0.67 10.1 0.0 3.1 3 0 0 3 3 3 1 AAA domain DUF87 PF01935.17 KXS21124.1 - 0.00053 20.1 1.4 2.3 8.3 0.0 3.7 4 0 0 4 4 4 1 Helicase HerA, central domain NACHT PF05729.12 KXS21124.1 - 0.00086 19.3 0.6 0.33 10.8 0.0 2.8 3 0 0 3 3 2 1 NACHT domain Arf PF00025.21 KXS21124.1 - 0.0018 17.7 2.2 1.4 8.3 0.0 3.5 5 0 0 5 5 3 2 ADP-ribosylation factor family AAA_30 PF13604.6 KXS21124.1 - 0.002 17.9 1.9 0.24 11.1 0.0 3.2 3 1 0 3 3 2 1 AAA domain Dynamin_N PF00350.23 KXS21124.1 - 0.003 17.6 5.4 0.33 11.0 0.0 3.9 2 1 1 3 3 3 1 Dynamin family cobW PF02492.19 KXS21124.1 - 0.0049 16.5 0.2 2.6 7.6 0.0 2.6 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.22 KXS21124.1 - 0.011 16.1 0.0 1.2 9.6 0.0 2.8 2 0 0 2 2 2 0 RNA helicase Roc PF08477.13 KXS21124.1 - 0.015 15.5 0.0 4.1 7.6 0.0 3.1 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase DUF815 PF05673.13 KXS21124.1 - 0.019 14.1 0.0 2.6 7.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Zeta_toxin PF06414.12 KXS21124.1 - 0.025 13.9 0.0 2 7.7 0.0 2.7 2 0 0 2 2 2 0 Zeta toxin NB-ARC PF00931.22 KXS21124.1 - 0.027 13.6 0.3 2.9 7.0 0.0 3.1 3 0 0 3 3 3 0 NB-ARC domain AAA_27 PF13514.6 KXS21124.1 - 0.028 14.0 10.2 2.9 7.4 0.0 3.7 4 0 0 4 4 4 0 AAA domain AAA PF00004.29 KXS21124.1 - 0.033 14.6 0.0 2.2 8.7 0.0 2.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_13 PF13166.6 KXS21124.1 - 0.037 12.7 3.3 9.5 4.7 1.8 3.2 3 0 0 3 3 3 0 AAA domain Cob_adeno_trans PF01923.18 KXS21124.1 - 0.068 13.3 0.3 0.21 11.7 0.1 1.9 2 0 0 2 2 1 0 Cobalamin adenosyltransferase TsaE PF02367.17 KXS21124.1 - 0.087 12.8 0.3 3.2 7.8 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Rad17 PF03215.15 KXS21124.1 - 0.092 12.7 0.0 1.8 8.4 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain MeaB PF03308.16 KXS21124.1 - 0.14 11.1 5.8 0.77 8.7 0.1 2.9 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Peripla_BP_2 PF01497.18 KXS21124.1 - 0.15 11.6 2.7 0.41 10.2 2.7 1.7 1 0 0 1 1 1 0 Periplasmic binding protein EDR1 PF14381.6 KXS21124.1 - 0.21 11.3 2.1 1.8 8.2 1.0 2.6 2 0 0 2 2 2 0 Ethylene-responsive protein kinase Le-CTR1 Vfa1 PF08432.10 KXS21124.1 - 0.36 11.2 5.4 0.67 10.3 5.4 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Thymidylate_kin PF02223.17 KXS21124.1 - 0.47 10.1 3.5 8.3 6.0 0.0 3.1 3 0 0 3 3 3 0 Thymidylate kinase AAA_10 PF12846.7 KXS21124.1 - 0.59 9.0 7.4 5.1 5.9 0.0 3.2 3 1 0 3 3 3 0 AAA-like domain ADIP PF11559.8 KXS21124.1 - 0.63 10.1 7.4 1.2 9.2 7.4 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF3584 PF12128.8 KXS21124.1 - 1.4 6.3 12.6 3.7 4.9 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3584) AAA_17 PF13207.6 KXS21124.1 - 1.8 9.0 9.0 22 5.5 0.2 3.8 3 0 0 3 3 3 0 AAA domain Glyco_hydro_16 PF00722.21 KXS21125.1 - 1.3e-26 93.1 0.7 2e-26 92.6 0.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Surp PF01805.20 KXS21126.1 - 2.7e-41 139.3 6.3 4.2e-20 71.5 0.7 2.4 2 0 0 2 2 2 2 Surp module PRP21_like_P PF12230.8 KXS21126.1 - 1.1e-25 90.8 0.2 1.8e-25 90.1 0.2 1.3 1 0 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein DUF1682 PF07946.14 KXS21126.1 - 0.005 16.1 1.9 0.0069 15.6 1.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) Toprim_Crpt PF13342.6 KXS21126.1 - 0.15 12.1 0.1 0.51 10.4 0.0 1.9 2 0 0 2 2 2 0 C-terminal repeat of topoisomerase Chorion_3 PF05387.11 KXS21128.1 - 0.079 12.6 0.6 0.14 11.8 0.6 1.3 1 0 0 1 1 1 0 Chorion family 3 F-box PF00646.33 KXS21128.1 - 0.086 12.8 6.7 16 5.5 0.0 4.3 4 0 0 4 4 4 0 F-box domain GTP_EFTU PF00009.27 KXS21129.1 - 3.7e-55 186.5 0.0 6.7e-55 185.7 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 KXS21129.1 - 5e-16 58.5 0.0 1.5e-15 57.0 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KXS21129.1 - 5.5e-16 58.7 0.0 1.9e-15 57.0 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.6 KXS21129.1 - 1.5e-08 34.6 0.0 3.3e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.18 KXS21129.1 - 0.0042 16.9 0.0 0.022 14.5 0.0 2.3 2 0 0 2 2 2 1 Elongation factor G, domain IV MMR_HSR1 PF01926.23 KXS21129.1 - 0.011 15.8 0.0 0.039 14.0 0.0 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase E1-E2_ATPase PF00122.20 KXS21130.1 - 4.2e-45 153.5 4.0 1.4e-44 151.8 2.1 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KXS21130.1 - 1.2e-21 77.2 16.4 3.6e-16 59.4 5.0 3.7 4 0 0 4 4 4 2 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 KXS21130.1 - 3e-17 62.5 0.0 7e-17 61.3 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KXS21130.1 - 1.6e-15 57.9 1.3 2.1e-12 47.8 1.3 3.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KXS21130.1 - 4.9e-15 55.0 0.0 9.9e-15 54.0 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KXS21130.1 - 0.00024 20.9 1.4 0.048 13.4 0.5 2.7 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Gate PF07670.14 KXS21130.1 - 0.79 10.0 6.8 0.17 12.2 2.6 2.1 2 0 0 2 2 2 0 Nucleoside recognition ubiquitin PF00240.23 KXS21131.1 - 0.0023 17.6 0.0 0.0042 16.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 KXS21131.1 - 0.014 16.0 0.0 0.032 14.8 0.0 1.6 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain bZIP_2 PF07716.15 KXS21132.1 - 6.9e-07 29.3 13.5 1.7e-06 28.0 13.8 1.5 1 1 1 2 2 2 2 Basic region leucine zipper SurA_N_2 PF13623.6 KXS21132.1 - 0.11 12.4 0.9 0.12 12.3 0.9 1.0 1 0 0 1 1 1 0 SurA N-terminal domain bZIP_1 PF00170.21 KXS21132.1 - 0.28 11.3 6.9 2.5 8.3 4.5 2.0 2 0 0 2 2 2 0 bZIP transcription factor Fasciclin PF02469.22 KXS21133.1 - 9e-20 71.2 0.2 1.7e-16 60.6 0.0 2.3 2 0 0 2 2 2 2 Fasciclin domain BRO1 PF03097.18 KXS21134.1 - 3.5e-125 417.8 0.1 5.7e-125 417.2 0.1 1.3 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 KXS21134.1 - 4.5e-59 200.2 2.1 4.5e-59 200.2 2.1 1.8 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV RMP PF14996.6 KXS21135.1 - 2.7e-28 99.2 0.2 6.1e-28 98.0 0.0 1.6 2 0 0 2 2 2 1 Retinal Maintenance RNA_pol_Rpb2_6 PF00562.28 KXS21136.1 - 6.6e-123 410.6 0.1 1.1e-122 409.8 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KXS21136.1 - 7.4e-54 182.3 0.0 1.1e-53 181.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 KXS21136.1 - 3.4e-31 107.5 0.1 7.2e-31 106.5 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 KXS21136.1 - 2.8e-27 95.6 0.0 7.6e-27 94.2 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.13 KXS21136.1 - 3.6e-24 84.8 0.2 1.1e-23 83.3 0.2 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 KXS21136.1 - 1.2e-19 70.2 0.0 3.8e-19 68.6 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 KXS21136.1 - 1.7e-09 38.1 0.0 5.6e-09 36.4 0.0 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 E1-E2_ATPase PF00122.20 KXS21137.1 - 8.8e-26 90.5 5.0 1.4e-21 76.8 2.1 2.9 2 0 0 2 2 2 2 E1-E2 ATPase Hydrolase PF00702.26 KXS21137.1 - 1e-12 48.8 0.0 2.1e-06 28.2 0.0 2.8 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KXS21137.1 - 0.0025 17.5 0.1 0.0025 17.5 0.1 1.8 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 KXS21137.1 - 0.16 12.1 0.0 0.35 11.0 0.0 1.5 1 0 0 1 1 1 0 Cation transport ATPase (P-type) DUF998 PF06197.13 KXS21137.1 - 0.58 9.7 9.4 0.059 13.0 3.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF998) PPTA PF01239.22 KXS21138.1 - 1.3e-06 28.0 3.5 0.0016 18.1 0.0 3.2 3 0 0 3 3 3 2 Protein prenyltransferase alpha subunit repeat DUF4110 PF13422.6 KXS21138.1 - 0.12 12.5 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4110) ZZ PF00569.17 KXS21139.1 - 1.8e-12 46.8 2.8 1.8e-12 46.8 2.8 1.9 2 0 0 2 2 2 1 Zinc finger, ZZ type EF-hand_1 PF00036.32 KXS21139.1 - 9.8e-06 24.8 0.9 2.1e-05 23.7 0.9 1.6 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.6 KXS21139.1 - 0.0002 20.7 1.1 0.00046 19.5 1.1 1.6 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KXS21139.1 - 0.00052 19.7 0.2 0.0014 18.4 0.2 1.7 1 0 0 1 1 1 1 EF-hand domain EF-hand_8 PF13833.6 KXS21139.1 - 0.033 14.0 0.0 0.079 12.8 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_7 PF13499.6 KXS21139.1 - 0.034 14.6 0.3 0.12 12.8 0.0 2.0 2 0 0 2 2 2 0 EF-hand domain pair RINGv PF12906.7 KXS21140.1 - 4.9e-14 52.2 8.2 7.1e-14 51.7 8.2 1.2 1 0 0 1 1 1 1 RING-variant domain FANCL_C PF11793.8 KXS21140.1 - 0.01 16.0 5.8 0.021 15.0 5.8 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain PHD PF00628.29 KXS21140.1 - 0.015 15.2 8.7 0.022 14.6 8.7 1.3 1 0 0 1 1 1 0 PHD-finger zf-RING_2 PF13639.6 KXS21140.1 - 0.15 12.4 6.6 0.23 11.8 6.6 1.3 1 0 0 1 1 1 0 Ring finger domain RNA_POL_M_15KD PF02150.16 KXS21140.1 - 0.22 11.4 2.8 0.48 10.3 2.8 1.5 1 0 0 1 1 1 0 RNA polymerases M/15 Kd subunit Acyltransferase PF01553.21 KXS21141.1 - 2.8e-20 72.3 0.0 5.1e-20 71.5 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase HTH_Crp_2 PF13545.6 KXS21141.1 - 0.094 12.7 0.1 4.5 7.3 0.0 3.2 3 0 0 3 3 3 0 Crp-like helix-turn-helix domain DEC-1_N PF04625.13 KXS21141.1 - 0.12 11.3 2.0 0.19 10.7 2.0 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region DHBP_synthase PF00926.19 KXS21142.1 - 9.5e-87 289.5 0.6 1.5e-86 288.8 0.2 1.6 2 0 0 2 2 2 1 3,4-dihydroxy-2-butanone 4-phosphate synthase Lum_binding PF00677.17 KXS21142.1 - 5e-45 151.4 1.4 7e-22 77.2 0.0 2.6 2 0 0 2 2 2 2 Lumazine binding domain Ring_hydroxyl_A PF00848.19 KXS21143.1 - 1e-13 51.8 0.3 4.4e-10 39.9 0.0 2.1 2 0 0 2 2 2 2 Ring hydroxylating alpha subunit (catalytic domain) DUF1010 PF06231.11 KXS21143.1 - 0.87 10.1 4.7 4.8 7.8 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1010) Mito_carr PF00153.27 KXS21144.1 - 6.8e-31 106.0 8.4 2.2e-16 59.5 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Abhydrolase_1 PF00561.20 KXS21145.1 - 5.2e-10 39.4 0.0 6.5e-08 32.5 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXS21145.1 - 5e-09 35.8 0.0 0.00012 21.5 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KXS21145.1 - 6.8e-05 23.6 0.0 0.00013 22.7 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.13 KXS21145.1 - 8.1e-05 22.4 0.0 0.00011 21.9 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) DUF818 PF05677.12 KXS21145.1 - 0.0029 16.6 0.0 0.0049 15.9 0.0 1.3 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Peptidase_S9 PF00326.21 KXS21145.1 - 0.078 12.4 0.0 0.2 11.1 0.0 1.6 2 0 0 2 2 2 0 Prolyl oligopeptidase family PEP_mutase PF13714.6 KXS21146.1 - 4.5e-50 170.3 0.1 5.1e-50 170.1 0.1 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 KXS21146.1 - 4.6e-11 41.9 0.2 6.6e-11 41.4 0.2 1.2 1 0 0 1 1 1 1 Isocitrate lyase family PhoD PF09423.10 KXS21147.1 - 4.9e-90 302.1 1.9 1.1e-65 222.0 1.1 2.1 1 1 1 2 2 2 2 PhoD-like phosphatase PhoD_N PF16655.5 KXS21147.1 - 6e-16 58.8 0.0 2.1e-15 57.0 0.0 2.0 1 1 0 1 1 1 1 PhoD-like phosphatase, N-terminal domain Pur_ac_phosph_N PF16656.5 KXS21147.1 - 0.019 15.6 0.0 0.045 14.3 0.0 1.8 1 1 0 1 1 1 0 Purple acid Phosphatase, N-terminal domain Metallophos PF00149.28 KXS21147.1 - 0.038 14.5 4.3 0.22 12.0 1.9 2.3 1 1 1 2 2 2 0 Calcineurin-like phosphoesterase Longin PF13774.6 KXS21148.1 - 1.6e-13 50.5 0.1 4.1e-13 49.2 0.1 1.7 1 0 0 1 1 1 1 Regulated-SNARE-like domain DUF3429 PF11911.8 KXS21148.1 - 0.13 12.6 7.5 0.25 11.6 7.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3429) Med21 PF11221.8 KXS21149.1 - 0.0089 16.3 0.1 0.01 16.1 0.1 1.2 1 0 0 1 1 1 1 Subunit 21 of Mediator complex DUF3439 PF11921.8 KXS21149.1 - 0.055 13.4 0.1 0.16 11.9 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Cas_Csy4 PF09618.10 KXS21149.1 - 0.23 11.6 1.0 0.32 11.1 1.0 1.4 1 1 0 1 1 1 0 CRISPR-associated protein (Cas_Csy4) UQ_con PF00179.26 KXS21150.1 - 1.5e-45 154.3 0.0 1.8e-45 154.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA PF00627.31 KXS21150.1 - 1.4e-10 40.8 0.1 3.4e-10 39.6 0.0 1.6 2 0 0 2 2 2 1 UBA/TS-N domain UBA_3 PF09288.10 KXS21150.1 - 0.0021 17.8 0.0 0.0043 16.8 0.0 1.5 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain Prok-E2_B PF14461.6 KXS21150.1 - 0.0091 15.7 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KXS21150.1 - 0.095 13.0 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 RWD domain UBA_6 PF18039.1 KXS21150.1 - 0.11 12.5 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 UBA-like domain UBA_2 PF08587.11 KXS21150.1 - 0.16 12.1 0.0 0.38 10.9 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin associated domain (UBA) PfkB PF00294.24 KXS21152.1 - 7e-23 81.4 0.0 9.4e-23 81.0 0.0 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Skp1 PF01466.19 KXS21154.1 - 8.6e-30 102.6 0.7 1.5e-29 101.9 0.7 1.4 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 KXS21154.1 - 1.6e-24 85.8 1.2 3.8e-24 84.6 0.1 2.2 2 1 1 3 3 3 1 Skp1 family, tetramerisation domain Anti-adapt_IraP PF10796.9 KXS21154.1 - 0.045 14.3 0.0 0.082 13.5 0.0 1.5 1 0 0 1 1 1 0 Sigma-S stabilisation anti-adaptor protein Mit_KHE1 PF10173.9 KXS21155.1 - 6.1e-11 42.8 0.0 9.9e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related XRCC4 PF06632.12 KXS21156.1 - 0.35 9.7 3.6 0.42 9.4 3.6 1.1 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 DUF4692 PF15763.5 KXS21157.1 - 0.5 10.8 2.2 1.3 9.5 2.2 1.6 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) RGS PF00615.19 KXS21158.1 - 2.3e-08 34.3 0.0 4.4e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Regulator of G protein signaling domain DUF2370 PF10176.9 KXS21159.1 - 3.4e-40 138.1 0.3 3.2e-32 112.0 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF2370) 5HT_transport_N PF03491.13 KXS21160.1 - 0.1 12.8 1.5 0.2 11.9 0.0 2.2 2 0 0 2 2 2 0 Serotonin (5-HT) neurotransmitter transporter, N-terminus UNC-93 PF05978.16 KXS21160.1 - 0.29 10.8 4.8 7 6.3 4.6 3.2 1 1 0 1 1 1 0 Ion channel regulatory protein UNC-93 Phage_holin_5_1 PF06946.11 KXS21160.1 - 0.47 10.9 3.5 1.8 9.0 3.5 2.0 1 0 0 1 1 1 0 Bacteriophage A118-like holin, Hol118 MFS_1 PF07690.16 KXS21161.1 - 3.7e-32 111.6 49.1 2.1e-29 102.6 14.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXS21161.1 - 4.7e-11 42.2 0.5 4.7e-11 42.2 0.5 2.5 2 1 1 3 3 3 1 Sugar (and other) transporter MFS_4 PF06779.14 KXS21161.1 - 8e-06 25.4 1.5 1.8e-05 24.2 1.5 1.6 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB DUF2085 PF09858.9 KXS21161.1 - 1.9 9.0 7.7 1 9.9 0.2 3.5 3 0 0 3 3 3 0 Predicted membrane protein (DUF2085) UBD PF16455.5 KXS21163.1 - 2.9e-24 85.3 0.0 3.8e-24 84.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-binding domain ubiquitin PF00240.23 KXS21163.1 - 3.7e-05 23.4 0.0 6.4e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family SUIM_assoc PF16619.5 KXS21163.1 - 0.042 13.9 0.1 0.073 13.1 0.1 1.5 1 1 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Rad60-SLD_2 PF13881.6 KXS21163.1 - 0.094 12.8 0.0 0.18 11.9 0.0 1.5 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like SNF2_N PF00176.23 KXS21164.1 - 7.4e-35 120.3 0.0 1.3e-34 119.5 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KXS21164.1 - 2.7e-13 50.2 0.3 7.5e-13 48.8 0.3 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 KXS21164.1 - 0.00063 19.0 0.3 0.0011 18.3 0.3 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase SWI2_SNF2 PF18766.1 KXS21164.1 - 0.041 13.6 0.0 0.85 9.2 0.0 2.4 2 0 0 2 2 2 0 SWI2/SNF2 ATPase ResIII PF04851.15 KXS21164.1 - 0.11 12.5 0.0 3.8 7.5 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit GCIP PF13324.6 KXS21164.1 - 0.23 11.0 1.5 0.41 10.2 0.2 1.9 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting MRP_L53 PF10780.9 KXS21167.1 - 2.9e-09 37.0 0.0 4.4e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 WH2 PF02205.20 KXS21168.1 - 3.4e-07 29.9 0.2 3.9e-05 23.3 0.0 2.9 2 0 0 2 2 2 1 WH2 motif DUF1131 PF06572.12 KXS21168.1 - 0.0086 15.8 0.1 0.017 14.8 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1131) ZapB PF06005.12 KXS21168.1 - 0.92 10.0 0.0 0.92 10.0 0.0 3.8 4 1 0 4 4 4 0 Cell division protein ZapB AAA_23 PF13476.6 KXS21169.1 - 0.71 10.3 13.2 1 9.8 13.2 1.2 1 0 0 1 1 1 0 AAA domain DUF4637 PF15470.6 KXS21170.1 - 0.06 13.1 0.3 1.1 8.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) bZIP_1 PF00170.21 KXS21171.1 - 3.1e-07 30.4 13.0 7.2e-07 29.2 13.0 1.6 1 0 0 1 1 1 1 bZIP transcription factor YabA PF06156.13 KXS21171.1 - 0.0022 18.6 0.9 0.015 15.9 0.1 2.6 3 0 0 3 3 3 1 Initiation control protein YabA zf-C4H2 PF10146.9 KXS21171.1 - 0.074 13.4 0.1 0.074 13.4 0.1 3.2 3 1 1 4 4 4 0 Zinc finger-containing protein SOGA PF11365.8 KXS21171.1 - 0.086 14.0 0.1 0.086 14.0 0.1 3.0 3 0 0 3 3 3 0 Protein SOGA DnaJ_C PF01556.18 KXS21172.1 - 6.2e-29 101.0 0.0 8.3e-29 100.6 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KXS21172.1 - 2.5e-16 59.6 0.7 1.5e-10 41.0 0.0 3.1 3 0 0 3 3 3 2 DnaJ domain Fungal_trans PF04082.18 KXS21175.1 - 3e-08 33.0 0.1 4.9e-08 32.3 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXS21175.1 - 4.6e-07 29.8 13.6 7.2e-07 29.2 13.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXS21176.1 - 1.6e-15 56.9 0.0 3e-15 56.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXS21176.1 - 4.3e-07 29.9 8.7 7e-07 29.3 8.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PIP5K PF01504.18 KXS21177.1 - 3.7e-81 272.4 0.0 5.7e-81 271.7 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Abhydrolase_1 PF00561.20 KXS21178.1 - 6.3e-41 140.7 0.0 1.9e-40 139.1 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 KXS21178.1 - 0.00038 20.5 0.0 0.0027 17.8 0.0 2.5 2 0 0 2 2 2 1 TAP-like protein Hydrolase_4 PF12146.8 KXS21178.1 - 0.0081 15.4 0.0 0.075 12.3 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KXS21178.1 - 0.015 15.9 19.9 0.039 14.6 20.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family Gln-synt_C PF00120.24 KXS21179.1 - 1.2e-86 290.9 0.0 1.5e-86 290.5 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 KXS21179.1 - 0.0017 18.1 0.0 0.61 9.9 0.0 2.5 2 0 0 2 2 2 2 Glutamine synthetase, beta-Grasp domain Glyco_transf_7C PF02709.14 KXS21179.1 - 0.093 12.4 0.0 0.23 11.1 0.0 1.7 1 0 0 1 1 1 0 N-terminal domain of galactosyltransferase Gln-synt_N_2 PF16952.5 KXS21179.1 - 0.18 11.7 0.0 0.52 10.2 0.0 1.7 1 1 1 2 2 2 0 Glutamine synthetase N-terminal domain SRR1 PF07985.12 KXS21180.1 - 4.1e-10 39.5 0.0 7.5e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 SRR1 ChAPs PF09295.10 KXS21181.1 - 4.7e-117 391.3 0.0 7.1e-95 318.3 0.0 2.1 2 0 0 2 2 2 2 ChAPs (Chs5p-Arf1p-binding proteins) TPR_19 PF14559.6 KXS21181.1 - 8.9e-05 22.9 0.2 0.21 12.1 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KXS21181.1 - 0.13 12.6 0.1 6 7.3 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Ribosomal_S25 PF03297.15 KXS21182.1 - 5.4e-42 142.1 5.2 5.4e-42 142.1 5.2 2.0 2 0 0 2 2 2 1 S25 ribosomal protein Hrs_helical PF12210.8 KXS21182.1 - 0.028 14.9 0.0 0.047 14.2 0.0 1.4 1 0 0 1 1 1 0 Hepatocyte growth factor-regulated tyrosine kinase substrate RNase_H PF00075.24 KXS21183.1 - 7.5e-08 32.7 0.1 9.8e-08 32.3 0.1 1.2 1 0 0 1 1 1 1 RNase H Sel1 PF08238.12 KXS21184.1 - 7.3e-96 312.4 39.3 1.2e-12 48.0 0.1 13.2 12 1 0 12 12 12 12 Sel1 repeat Pkinase_Tyr PF07714.17 KXS21184.1 - 2.5e-42 145.0 0.0 3.5e-42 144.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXS21184.1 - 1.2e-37 129.7 0.0 1.7e-37 129.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 KXS21184.1 - 9.9e-08 31.6 0.0 1.6e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like TPR_16 PF13432.6 KXS21184.1 - 1.6e-05 25.4 14.6 0.029 15.0 0.1 6.1 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 KXS21184.1 - 0.0076 16.2 1.9 25 5.2 0.0 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat RIO1 PF01163.22 KXS21184.1 - 0.11 12.0 0.0 0.52 9.9 0.0 2.0 2 0 0 2 2 2 0 RIO1 family TPR_6 PF13174.6 KXS21184.1 - 0.13 13.0 7.5 53 4.8 0.0 6.8 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_8 PF13181.6 KXS21184.1 - 0.6 10.5 10.8 27 5.3 0.1 7.2 7 2 0 7 7 7 0 Tetratricopeptide repeat TPR_1 PF00515.28 KXS21184.1 - 2 8.3 25.1 1.7 8.6 0.1 9.0 11 1 0 11 11 11 0 Tetratricopeptide repeat TPR_12 PF13424.6 KXS21184.1 - 2.4 8.5 11.9 19 5.6 0.5 5.4 4 3 0 4 4 4 0 Tetratricopeptide repeat Abhydrolase_3 PF07859.13 KXS21185.1 - 1.6e-28 100.0 0.0 2.6e-28 99.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KXS21185.1 - 3.7e-05 22.7 0.0 5.6e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase COesterase PF00135.28 KXS21185.1 - 0.00011 21.3 0.5 0.00047 19.2 0.0 2.0 2 0 0 2 2 2 1 Carboxylesterase family Pex16 PF08610.10 KXS21186.1 - 1.5e-50 172.2 0.1 6.3e-44 150.5 0.0 2.5 2 1 0 2 2 2 2 Peroxisomal membrane protein (Pex16) ANAPC4_WD40 PF12894.7 KXS21187.1 - 4.2e-12 46.2 0.9 0.0033 17.7 0.0 6.5 2 2 4 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KXS21187.1 - 1.9e-09 38.0 14.1 0.043 14.7 0.0 7.9 8 1 0 8 8 8 3 WD domain, G-beta repeat eIF2A PF08662.11 KXS21187.1 - 2.4e-09 37.3 0.0 0.027 14.4 0.0 5.1 2 2 1 5 5 5 3 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 KXS21187.1 - 1.9e-08 34.0 11.3 0.56 10.2 0.1 6.3 7 0 0 7 7 7 4 WD40-like Beta Propeller Repeat IKI3 PF04762.12 KXS21187.1 - 0.00016 19.8 0.4 0.33 8.9 0.0 3.2 2 1 1 3 3 3 2 IKI3 family TruB_C PF09142.11 KXS21187.1 - 0.0018 18.0 0.3 4.1 7.2 0.0 4.5 5 0 0 5 5 5 1 tRNA Pseudouridine synthase II, C terminal DPPIV_N PF00930.21 KXS21187.1 - 0.006 15.4 1.1 11 4.7 0.0 3.8 2 1 0 4 4 4 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Coatomer_WDAD PF04053.14 KXS21187.1 - 0.0078 15.3 0.0 0.016 14.2 0.0 1.6 1 1 0 1 1 1 1 Coatomer WD associated region DUF1513 PF07433.11 KXS21187.1 - 0.025 13.7 0.0 5 6.1 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1513) Proteasome_A_N PF10584.9 KXS21187.1 - 8.9 6.1 7.6 55 3.6 0.0 4.5 6 0 0 6 6 6 0 Proteasome subunit A N-terminal signature Glyco_transf_10 PF00852.19 KXS21188.1 - 6e-13 48.9 0.0 2.6e-08 33.8 0.0 3.0 3 0 0 3 3 3 3 Glycosyltransferase family 10 (fucosyltransferase) C-term Ribosomal_L27A PF00828.19 KXS21189.1 - 4.9e-29 101.6 0.0 7.9e-29 100.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Histidinol_dh PF00815.20 KXS21191.1 - 1.2e-148 495.5 1.7 1.4e-148 495.2 1.7 1.1 1 0 0 1 1 1 1 Histidinol dehydrogenase DUF2868 PF11067.8 KXS21191.1 - 0.07 12.6 0.9 0.088 12.3 0.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2868) ABC_tran_CTD PF16326.5 KXS21191.1 - 0.088 13.1 0.5 0.18 12.1 0.5 1.4 1 0 0 1 1 1 0 ABC transporter C-terminal domain ABC2_membrane PF01061.24 KXS21192.1 - 3e-24 85.6 22.6 3e-24 85.6 22.6 2.0 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 KXS21192.1 - 1.9e-21 77.0 0.0 6.6e-21 75.3 0.0 1.8 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 KXS21192.1 - 2.9e-06 27.3 0.2 0.0006 19.7 0.1 2.3 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KXS21192.1 - 0.00083 19.1 0.1 0.0049 16.6 0.0 2.2 2 0 0 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KXS21192.1 - 0.0012 18.8 0.1 0.016 15.1 0.2 2.1 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 KXS21192.1 - 0.0013 19.1 0.2 0.0096 16.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KXS21192.1 - 0.0015 19.0 0.0 0.005 17.2 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 KXS21192.1 - 0.0048 17.5 0.0 0.017 15.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 KXS21192.1 - 0.012 15.2 2.0 0.46 10.0 0.1 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.6 KXS21192.1 - 0.014 15.7 0.9 0.075 13.3 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KXS21192.1 - 0.021 14.5 1.4 0.96 9.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 KXS21192.1 - 0.04 14.4 0.1 0.067 13.7 0.1 1.2 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KXS21192.1 - 0.078 12.7 0.1 0.16 11.7 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA PF00004.29 KXS21192.1 - 0.08 13.4 0.5 0.54 10.7 0.0 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KXS21192.1 - 0.1 12.7 0.0 0.24 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KXS21192.1 - 0.26 11.2 0.9 0.64 9.9 0.1 2.1 3 0 0 3 3 3 0 NACHT domain ABC_tran PF00005.27 KXS21193.1 - 4.3e-22 79.1 0.0 8e-22 78.2 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 KXS21193.1 - 2.8e-12 46.5 17.7 2.8e-12 46.5 17.7 1.7 2 0 0 2 2 2 1 ABC-2 type transporter AAA_21 PF13304.6 KXS21193.1 - 6.7e-06 26.1 0.0 0.035 13.9 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KXS21193.1 - 0.00053 19.7 0.1 0.0013 18.4 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KXS21193.1 - 0.0052 16.7 0.0 0.014 15.4 0.0 1.7 1 0 0 1 1 1 1 RsgA GTPase AAA_18 PF13238.6 KXS21193.1 - 0.025 15.1 0.0 0.047 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KXS21193.1 - 0.026 14.9 0.0 0.057 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 KXS21193.1 - 0.03 14.8 0.0 0.073 13.6 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KXS21193.1 - 0.05 13.9 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 KXS21193.1 - 0.12 12.3 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain Arginase PF00491.21 KXS21194.1 - 2.4e-85 286.4 0.0 2.8e-85 286.2 0.0 1.0 1 0 0 1 1 1 1 Arginase family Hat1_N PF10394.9 KXS21195.1 - 1.9e-24 86.7 0.0 4.1e-24 85.6 0.0 1.6 1 1 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_1 PF00583.25 KXS21195.1 - 0.028 14.7 0.0 0.058 13.6 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family zf-C2H2 PF00096.26 KXS21196.1 - 8.8e-12 44.8 12.3 4.9e-06 26.7 1.5 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXS21196.1 - 4.9e-06 26.9 8.8 0.0062 17.3 0.8 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 KXS21196.1 - 0.15 12.5 6.0 3.7 8.1 0.9 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KXS21196.1 - 0.19 12.0 3.7 3.4 8.1 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KXS21196.1 - 5 7.2 9.5 2.1 8.5 1.3 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger Aminotran_1_2 PF00155.21 KXS21197.1 - 8.4e-59 199.6 0.0 9.8e-59 199.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 KXS21197.1 - 1.7e-05 24.2 0.0 2.3e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 KXS21197.1 - 0.0078 14.8 0.0 0.024 13.2 0.0 1.7 2 1 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_MocR PF12897.7 KXS21197.1 - 0.024 13.4 0.0 0.066 12.0 0.0 1.6 1 1 0 1 1 1 0 Alanine-glyoxylate amino-transferase DegT_DnrJ_EryC1 PF01041.17 KXS21197.1 - 0.042 13.2 0.0 0.068 12.5 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Nop16 PF09420.10 KXS21199.1 - 1e-33 117.1 6.4 5e-33 114.9 6.4 1.8 1 1 0 1 1 1 1 Ribosome biogenesis protein Nop16 Myb_DNA-binding PF00249.31 KXS21199.1 - 0.009 16.2 0.0 0.018 15.2 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF4142 PF13628.6 KXS21199.1 - 0.018 15.3 0.9 0.036 14.3 0.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4142) Radial_spoke PF04712.12 KXS21200.1 - 4.2e-118 395.4 0.0 4.2e-118 395.4 0.0 2.1 1 1 1 2 2 2 1 Radial spokehead-like protein SOG2 PF10428.9 KXS21200.1 - 0.16 11.1 14.1 0.23 10.6 14.1 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein KAR9 PF08580.10 KXS21200.1 - 3.5 6.0 12.6 5 5.5 12.6 1.2 1 0 0 1 1 1 0 Yeast cortical protein KAR9 SH3_9 PF14604.6 KXS21201.1 - 2.8e-06 27.1 0.0 7.2e-06 25.8 0.0 1.6 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 KXS21201.1 - 2.7e-05 23.7 0.0 5.3e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 SH3 domain EB PF01683.18 KXS21201.1 - 0.0072 16.6 9.0 0.0072 16.6 9.0 3.7 2 1 1 3 3 3 2 EB module DUF4436 PF14494.6 KXS21202.1 - 8.2e-12 44.9 3.3 9e-12 44.8 3.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4436) Peroxin-13_N PF04088.13 KXS21203.1 - 1.8e-33 115.9 0.0 2.6e-33 115.3 0.0 1.2 1 0 0 1 1 1 1 Peroxin 13, N-terminal region TetR PF13972.6 KXS21203.1 - 0.083 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial transcriptional repressor DUF4640 PF15480.6 KXS21203.1 - 0.18 11.6 0.0 0.62 9.8 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4640) Ank_2 PF12796.7 KXS21204.1 - 3e-20 72.6 0.0 0.01 16.4 0.0 6.6 4 2 3 7 7 7 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXS21204.1 - 6.5e-08 33.0 0.1 0.77 10.4 0.0 6.3 5 3 1 6 6 6 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXS21204.1 - 1.1e-07 31.6 5.9 10 7.0 0.0 9.7 12 0 0 12 12 12 2 Ankyrin repeat Ank_5 PF13857.6 KXS21204.1 - 0.0025 18.1 0.6 42 4.6 0.0 5.3 6 0 0 6 6 6 1 Ankyrin repeats (many copies) Beta-lactamase PF00144.24 KXS21205.1 - 9.7e-26 90.8 2.5 1.5e-25 90.2 2.5 1.2 1 0 0 1 1 1 1 Beta-lactamase DUF1664 PF07889.12 KXS21206.1 - 0.00013 21.9 7.6 0.0021 18.1 1.4 3.7 2 1 2 5 5 5 1 Protein of unknown function (DUF1664) Spc7 PF08317.11 KXS21206.1 - 0.0033 16.4 30.7 0.049 12.5 6.0 2.3 2 1 1 3 3 3 2 Spc7 kinetochore protein ATG16 PF08614.11 KXS21206.1 - 0.0043 17.3 29.4 0.15 12.3 11.3 2.3 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) DUF812 PF05667.11 KXS21206.1 - 0.0046 15.9 13.6 0.0066 15.4 13.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF812) DUF745 PF05335.13 KXS21206.1 - 0.013 15.2 26.0 0.02 14.6 12.2 3.1 2 1 2 4 4 4 0 Protein of unknown function (DUF745) DUF4200 PF13863.6 KXS21206.1 - 0.023 15.1 33.5 0.07 13.5 5.6 3.6 2 1 1 4 4 4 0 Domain of unknown function (DUF4200) MscS_porin PF12795.7 KXS21206.1 - 0.029 13.9 25.6 0.32 10.5 11.1 2.4 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain EzrA PF06160.12 KXS21206.1 - 0.036 12.2 14.7 0.17 10.1 7.4 2.2 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA ATP-synt_F6 PF05511.11 KXS21206.1 - 0.037 14.4 0.0 0.64 10.5 0.0 2.5 2 0 0 2 2 2 0 Mitochondrial ATP synthase coupling factor 6 Filament PF00038.21 KXS21206.1 - 0.12 11.9 27.7 0.72 9.4 8.8 3.9 2 1 3 5 5 5 0 Intermediate filament protein HrpB7 PF09486.10 KXS21206.1 - 0.28 11.5 42.3 0.24 11.8 11.6 4.2 2 1 2 4 4 4 0 Bacterial type III secretion protein (HrpB7) Allexi_40kDa PF05549.11 KXS21206.1 - 0.39 10.2 2.4 27 4.2 0.0 2.5 2 1 0 2 2 2 0 Allexivirus 40kDa protein FlaC_arch PF05377.11 KXS21206.1 - 0.74 10.3 6.8 0.38 11.2 1.1 3.2 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) TMPIT PF07851.13 KXS21206.1 - 0.88 8.8 10.9 3.7 6.7 6.5 2.2 2 0 0 2 2 2 0 TMPIT-like protein GAS PF13851.6 KXS21206.1 - 1.1 8.6 20.8 0.38 10.1 15.6 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Flagellin_N PF00669.20 KXS21206.1 - 1.3 9.1 8.7 5.1 7.2 0.4 2.9 3 0 0 3 3 3 0 Bacterial flagellin N-terminal helical region LMP PF04778.12 KXS21206.1 - 1.5 8.7 10.4 11 5.9 5.8 2.4 2 1 1 3 3 2 0 LMP repeated region TPR_MLP1_2 PF07926.12 KXS21206.1 - 1.8 8.6 40.6 0.45 10.6 17.7 3.0 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein Fzo_mitofusin PF04799.13 KXS21206.1 - 2.1 7.9 7.9 25 4.4 0.9 3.5 3 0 0 3 3 3 0 fzo-like conserved region SlyX PF04102.12 KXS21206.1 - 2.8 8.6 15.7 61 4.3 5.2 4.3 3 1 2 5 5 5 0 SlyX TMF_TATA_bd PF12325.8 KXS21206.1 - 5.3 7.3 29.0 19 5.5 0.0 4.1 3 1 1 4 4 4 0 TATA element modulatory factor 1 TATA binding Takusan PF04822.13 KXS21207.1 - 0.11 12.4 2.1 1.4 8.8 0.2 2.5 2 0 0 2 2 2 0 Takusan Ceramidase PF05875.12 KXS21209.1 - 1.7e-16 60.5 0.6 2.2e-16 60.1 0.6 1.1 1 0 0 1 1 1 1 Ceramidase GPI2 PF06432.11 KXS21209.1 - 0.049 13.1 2.3 0.25 10.8 1.3 2.1 1 1 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase DUF2304 PF10066.9 KXS21209.1 - 3.4 7.9 7.2 0.57 10.4 3.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) NupH_GANP PF16768.5 KXS21211.1 - 0.1 12.2 3.2 0.11 12.1 3.2 1.1 1 0 0 1 1 1 0 Nucleoporin homology of Germinal-centre associated nuclear protein Stevor PF17410.2 KXS21212.1 - 0.0041 16.7 0.1 0.005 16.4 0.1 1.1 1 0 0 1 1 1 1 Subtelomeric Variable Open Reading frame Dak1 PF02733.17 KXS21213.1 - 5.4e-103 344.1 0.0 8.5e-103 343.5 0.0 1.3 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 KXS21213.1 - 3.2e-33 115.1 4.3 8.9e-33 113.6 4.3 1.8 1 0 0 1 1 1 1 DAK2 domain 4HBT PF03061.22 KXS21214.1 - 4.4e-29 100.7 6.6 1.3e-16 60.7 0.9 2.3 2 0 0 2 2 2 2 Thioesterase superfamily MGC-24 PF05283.11 KXS21214.1 - 1.1 9.7 5.3 3 8.3 5.3 1.7 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF3377 PF11857.8 KXS21215.1 - 2.4 8.1 4.3 9.4 6.2 2.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) DUF21 PF01595.20 KXS21216.1 - 2.1e-39 135.0 0.2 4.2e-39 134.1 0.2 1.5 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 KXS21216.1 - 0.00035 21.0 0.1 0.36 11.3 0.0 3.0 3 0 0 3 3 3 2 CBS domain F-box-like PF12937.7 KXS21218.1 - 0.0033 17.3 1.5 0.021 14.7 0.1 2.4 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 KXS21218.1 - 0.16 11.9 0.4 0.36 10.8 0.1 1.7 2 0 0 2 2 2 0 F-box domain BTB PF00651.31 KXS21219.1 - 3.4e-06 27.2 0.0 6.6e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Ank_3 PF13606.6 KXS21220.1 - 0.004 17.5 1.6 0.15 12.7 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 KXS21220.1 - 0.0048 17.3 3.9 0.045 14.2 0.1 2.6 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.7 KXS21220.1 - 0.029 14.9 0.6 0.11 13.0 0.6 1.9 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXS21220.1 - 0.2 12.3 0.2 17 6.2 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeats (many copies) CDC45 PF02724.14 KXS21220.1 - 6.8 4.8 10.4 0.22 9.8 2.3 2.0 2 0 0 2 2 2 0 CDC45-like protein Coilin_N PF15862.5 KXS21220.1 - 9.6 6.0 7.8 0.25 11.1 0.7 2.0 2 0 0 2 2 2 0 Coilin N-terminus Globin PF00042.22 KXS21221.1 - 0.0023 18.5 0.0 0.31 11.6 0.0 2.5 2 0 0 2 2 2 1 Globin DivIC PF04977.15 KXS21221.1 - 0.0043 16.8 7.8 4.9 7.0 0.0 4.2 4 0 0 4 4 4 2 Septum formation initiator TolA_bind_tri PF16331.5 KXS21221.1 - 0.053 13.6 6.1 2.1 8.5 0.0 4.1 4 0 0 4 4 4 0 TolA binding protein trimerisation DUF1465 PF07323.12 KXS21221.1 - 0.071 12.9 0.6 8.3 6.2 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1465) ZapB PF06005.12 KXS21221.1 - 0.15 12.5 8.5 27 5.3 0.2 4.2 4 0 0 4 4 4 0 Cell division protein ZapB HALZ PF02183.18 KXS21221.1 - 0.65 10.3 7.3 5.9 7.2 0.1 3.8 3 0 0 3 3 3 0 Homeobox associated leucine zipper MscS_porin PF12795.7 KXS21221.1 - 0.66 9.5 4.8 1.1 8.7 0.2 3.0 3 0 0 3 3 3 0 Mechanosensitive ion channel porin domain GIT_CC PF16559.5 KXS21221.1 - 2.8 7.9 5.3 35 4.4 0.1 3.7 4 0 0 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor CtIP_N PF10482.9 KXS21221.1 - 4.9 7.2 5.4 8.5 6.5 0.4 3.0 3 0 0 3 3 3 0 Tumour-suppressor protein CtIP N-terminal domain TSC22 PF01166.18 KXS21221.1 - 5.4 7.4 8.5 32 4.9 0.1 4.0 5 0 0 5 5 5 0 TSC-22/dip/bun family bZIP_1 PF00170.21 KXS21221.1 - 5.8 7.1 8.3 77 3.5 0.1 4.1 4 0 0 4 4 4 0 bZIP transcription factor QWRF PF04484.12 KXS21222.1 - 3.8e-12 46.6 7.1 6.5e-12 45.8 7.1 1.5 1 1 0 1 1 1 1 QWRF family T3SSipB PF16535.5 KXS21222.1 - 1 9.8 7.2 2.9 8.4 5.0 2.4 2 1 0 2 2 2 0 Type III cell invasion protein SipB GATA PF00320.27 KXS21224.1 - 1.9e-12 46.5 4.0 3.6e-12 45.7 4.0 1.5 1 0 0 1 1 1 1 GATA zinc finger zf-NADH-PPase PF09297.11 KXS21224.1 - 1.2 8.8 4.3 16 5.2 1.4 2.5 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain CAF1 PF04857.20 KXS21225.1 - 1.1e-40 139.8 0.0 1.5e-20 73.6 0.0 2.0 2 0 0 2 2 2 2 CAF1 family ribonuclease CAP_N PF01213.19 KXS21225.1 - 3.3 7.1 16.0 3.7 7.0 1.9 2.8 3 0 0 3 3 3 0 Adenylate cyclase associated (CAP) N terminal Josephin PF02099.17 KXS21228.1 - 2.3e-20 73.3 0.1 4.3e-20 72.4 0.1 1.4 1 1 0 1 1 1 1 Josephin vATP-synt_E PF01991.18 KXS21230.1 - 2.5e-61 206.6 10.6 3e-61 206.3 10.6 1.1 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit RapH_N PF18801.1 KXS21230.1 - 0.086 12.9 2.6 0.14 12.3 1.0 2.3 2 0 0 2 2 2 0 response regulator aspartate phosphatase H, N terminal Sec10 PF07393.11 KXS21231.1 - 3.7e-176 587.6 2.4 4e-175 584.2 2.4 2.0 1 1 0 1 1 1 1 Exocyst complex component Sec10 SBDS_C PF09377.10 KXS21231.1 - 0.12 12.4 0.0 0.47 10.5 0.0 2.1 1 0 0 1 1 1 0 SBDS protein C-terminal domain PWI PF01480.17 KXS21231.1 - 0.12 12.7 0.1 2.5 8.5 0.0 2.8 2 0 0 2 2 2 0 PWI domain PrmA PF06325.13 KXS21232.1 - 1.3e-11 44.5 0.0 1.9e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 KXS21232.1 - 3.2e-11 43.8 0.1 1.2e-10 41.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXS21232.1 - 4.5e-09 36.3 0.0 6.9e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXS21232.1 - 6.4e-09 36.3 0.1 2.8e-08 34.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 KXS21232.1 - 2.3e-06 27.3 0.0 4e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 KXS21232.1 - 4.2e-06 26.7 0.0 7e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXS21232.1 - 4.1e-05 24.3 0.0 0.00018 22.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.7 KXS21232.1 - 7.3e-05 22.7 0.0 0.00012 22.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KXS21232.1 - 0.00016 21.1 0.0 0.00021 20.7 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.11 KXS21232.1 - 0.00077 18.5 0.0 0.0011 17.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Met_10 PF02475.16 KXS21232.1 - 0.00096 18.9 0.0 0.0014 18.4 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein TehB PF03848.14 KXS21232.1 - 0.0032 16.9 0.0 0.0049 16.3 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB PCMT PF01135.19 KXS21232.1 - 0.0036 17.1 0.0 0.0056 16.4 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.9 KXS21232.1 - 0.0037 17.0 0.0 0.0055 16.4 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_24 PF13578.6 KXS21232.1 - 0.013 16.5 0.0 0.024 15.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.19 KXS21232.1 - 0.014 15.5 0.0 0.025 14.7 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_2 PF00891.18 KXS21232.1 - 0.019 14.2 0.0 0.029 13.6 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_32 PF13679.6 KXS21232.1 - 0.073 13.1 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.15 KXS21232.1 - 0.2 11.3 0.0 0.32 10.6 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 AAA_5 PF07728.14 KXS21233.1 - 1.5e-82 274.4 0.0 1.2e-27 96.6 0.0 3.9 3 1 0 3 3 3 3 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KXS21233.1 - 3.8e-07 30.5 0.1 0.036 14.3 0.0 3.8 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KXS21233.1 - 5.9e-07 30.0 8.7 0.063 13.6 0.0 5.4 6 1 1 7 7 6 2 AAA ATPase domain Mg_chelatase PF01078.21 KXS21233.1 - 3.4e-06 26.6 0.0 0.13 11.6 0.0 3.4 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI CbbQ_C PF08406.10 KXS21233.1 - 0.00015 21.9 0.0 0.19 12.0 0.0 2.7 2 0 0 2 2 2 2 CbbQ/NirQ/NorQ C-terminal ABC_tran PF00005.27 KXS21233.1 - 0.00046 20.7 0.0 2 8.9 0.0 2.7 2 0 0 2 2 2 2 ABC transporter AAA_29 PF13555.6 KXS21233.1 - 0.0012 18.5 0.0 1.7 8.4 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_14 PF13173.6 KXS21233.1 - 0.0035 17.4 0.0 0.36 10.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KXS21233.1 - 0.0035 17.1 1.4 0.016 14.9 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_7 PF12775.7 KXS21233.1 - 0.0074 15.8 0.0 3.4 7.1 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_33 PF13671.6 KXS21233.1 - 0.015 15.4 1.8 0.24 11.5 0.0 3.0 3 0 0 3 3 2 0 AAA domain AAA_28 PF13521.6 KXS21233.1 - 0.047 13.9 0.0 0.18 12.0 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KXS21233.1 - 0.063 13.8 0.2 0.75 10.4 0.0 2.8 3 0 0 3 3 3 0 AAA domain Roc PF08477.13 KXS21233.1 - 0.066 13.4 0.0 4.9 7.4 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase RBB1NT PF08169.11 KXS21233.1 - 0.086 13.0 0.1 0.27 11.4 0.0 1.8 2 0 0 2 2 1 0 RBB1NT (NUC162) domain RNA_helicase PF00910.22 KXS21233.1 - 0.11 12.9 0.0 1.7 9.1 0.0 2.5 2 0 0 2 2 2 0 RNA helicase Viral_helicase1 PF01443.18 KXS21233.1 - 0.14 11.9 0.0 1.8 8.2 0.0 2.1 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase DUF974 PF06159.13 KXS21234.1 - 6.8e-69 232.4 0.0 3.2e-53 181.0 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF974) Trs65 PF12735.7 KXS21234.1 - 0.0046 16.4 0.3 0.021 14.3 0.1 2.1 2 0 0 2 2 2 1 TRAPP trafficking subunit Trs65 DUF4451 PF14616.6 KXS21235.1 - 0.067 13.4 0.2 3.4 7.9 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4451) Histone_HNS PF00816.21 KXS21237.1 - 0.028 15.2 10.7 2.1 9.2 0.4 3.8 2 1 2 4 4 4 0 H-NS histone family UPF0449 PF15136.6 KXS21237.1 - 0.44 11.0 4.9 4.5 7.8 0.1 2.7 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 T3SSipB PF16535.5 KXS21237.1 - 0.63 10.5 11.6 0.22 12.0 5.9 2.6 2 1 1 3 3 3 0 Type III cell invasion protein SipB ING PF12998.7 KXS21237.1 - 0.89 10.2 4.2 6.4 7.4 0.7 2.6 2 1 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding ATG16 PF08614.11 KXS21237.1 - 5.3 7.2 26.6 1.5 9.0 7.7 3.2 1 1 1 3 3 3 0 Autophagy protein 16 (ATG16) Fez1 PF06818.15 KXS21237.1 - 7.2 7.0 21.4 6.3 7.2 5.4 2.3 1 1 1 2 2 2 0 Fez1 tRNA_int_end_N2 PF12928.7 KXS21238.1 - 1.1e-15 57.5 0.1 1e-14 54.4 0.0 2.2 2 0 0 2 2 2 1 tRNA-splicing endonuclease subunit sen54 N-term Robl_LC7 PF03259.17 KXS21239.1 - 1.3e-27 95.4 0.0 1.4e-27 95.3 0.0 1.0 1 0 0 1 1 1 1 Roadblock/LC7 domain LAMTOR5 PF16672.5 KXS21239.1 - 7.8e-06 25.7 0.0 9.4e-06 25.5 0.0 1.1 1 0 0 1 1 1 1 Ragulator complex protein LAMTOR5 UPF0176_N PF17773.1 KXS21239.1 - 0.0058 17.0 0.0 0.0068 16.7 0.0 1.1 1 0 0 1 1 1 1 UPF0176 acylphosphatase like domain NUDIX PF00293.28 KXS21240.1 - 6.4e-23 81.2 0.1 8.2e-23 80.9 0.1 1.2 1 0 0 1 1 1 1 NUDIX domain Proteasome PF00227.26 KXS21241.1 - 5.3e-41 140.2 0.0 6.6e-41 139.9 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Ribonuc_L-PSP PF01042.21 KXS21243.1 - 1.8e-34 118.3 0.0 2.2e-34 118.0 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP cNMP_binding PF00027.29 KXS21244.1 - 9.1e-19 67.3 0.0 1.7e-18 66.5 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain PGA2 PF07543.12 KXS21244.1 - 0.049 13.6 0.6 0.11 12.5 0.6 1.5 1 0 0 1 1 1 0 Protein trafficking PGA2 TROVE PF05731.11 KXS21245.1 - 6.6e-52 177.0 2.4 4.7e-24 85.2 0.0 3.4 2 1 1 3 3 3 3 TROVE domain Complex1_LYR_2 PF13233.6 KXS21246.1 - 1.6e-10 41.6 0.0 2.9e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 KXS21246.1 - 0.024 14.7 0.5 0.05 13.7 0.5 1.5 1 0 0 1 1 1 0 Complex 1 protein (LYR family) zf-C2H2 PF00096.26 KXS21247.1 - 1.4e-05 25.2 7.1 0.016 15.6 0.3 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXS21247.1 - 0.00099 19.8 5.0 0.87 10.6 0.8 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KXS21247.1 - 0.011 16.1 2.6 0.17 12.3 0.2 2.9 2 0 0 2 2 2 0 Zinc-finger double domain MCPVI PF02993.14 KXS21247.1 - 0.57 10.0 2.4 1.2 8.9 2.4 1.5 1 0 0 1 1 1 0 Minor capsid protein VI Hemerythrin PF01814.23 KXS21249.1 - 6e-10 39.8 0.2 7.9e-10 39.5 0.2 1.1 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain PDZ_1 PF12812.7 KXS21250.1 - 3e-28 97.7 0.0 9.7e-18 64.0 0.0 3.2 2 0 0 2 2 2 2 PDZ-like domain Trypsin_2 PF13365.6 KXS21250.1 - 1.6e-18 68.0 0.6 5.9e-17 63.0 0.0 2.6 2 0 0 2 2 2 1 Trypsin-like peptidase domain PDZ_6 PF17820.1 KXS21250.1 - 3.9e-12 45.8 0.0 0.0014 18.5 0.0 4.5 4 0 0 4 4 4 2 PDZ domain PDZ_2 PF13180.6 KXS21250.1 - 6.8e-10 39.1 0.1 0.48 10.8 0.1 5.6 5 1 0 5 5 5 2 PDZ domain PDZ PF00595.24 KXS21250.1 - 4.3e-05 23.8 0.0 0.49 10.8 0.0 3.6 3 0 0 3 3 3 1 PDZ domain Trypsin PF00089.26 KXS21250.1 - 0.00089 19.1 0.0 0.0024 17.7 0.0 1.6 1 1 0 1 1 1 1 Trypsin Peptidase_S7 PF00949.21 KXS21250.1 - 0.018 14.8 0.9 0.053 13.3 0.9 1.7 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease DUF31 PF01732.16 KXS21250.1 - 0.078 12.5 0.5 0.11 12.0 0.5 1.2 1 0 0 1 1 1 0 Putative peptidase (DUF31) Peptidase_S46 PF10459.9 KXS21250.1 - 0.092 11.4 2.8 0.087 11.4 1.3 1.6 2 0 0 2 2 2 0 Peptidase S46 Troponin-I_N PF11636.8 KXS21251.1 - 0.83 9.7 5.1 0.12 12.3 1.0 1.8 2 0 0 2 2 2 0 Troponin I residues 1-32 Ribosomal_L7Ae PF01248.26 KXS21252.1 - 9.7e-22 76.5 0.3 2.5e-21 75.2 0.3 1.7 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 KXS21252.1 - 0.011 15.8 0.0 0.019 15.0 0.0 1.4 1 0 0 1 1 1 0 RNase P subunit Pop3 AAA_16 PF13191.6 KXS21252.1 - 0.13 12.7 0.0 0.4 11.0 0.0 1.7 1 1 1 2 2 2 0 AAA ATPase domain CLPTM1 PF05602.12 KXS21252.1 - 0.14 11.1 0.1 0.19 10.7 0.1 1.2 1 0 0 1 1 1 0 Cleft lip and palate transmembrane protein 1 (CLPTM1) CoA_transf_3 PF02515.17 KXS21253.1 - 2.5e-29 102.6 0.1 2.9e-19 69.5 0.2 2.2 2 0 0 2 2 2 2 CoA-transferase family III Ribosomal_S26e PF01283.19 KXS21253.1 - 0.056 13.9 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein S26e EB PF01683.18 KXS21254.1 - 0.027 14.8 9.1 0.027 14.8 9.1 3.0 1 1 1 2 2 2 0 EB module SH3_1 PF00018.28 KXS21254.1 - 0.05 13.2 0.0 0.076 12.6 0.0 1.3 1 0 0 1 1 1 0 SH3 domain SH3_9 PF14604.6 KXS21254.1 - 0.062 13.2 0.1 0.15 11.9 0.0 1.7 2 0 0 2 2 2 0 Variant SH3 domain DUF2154 PF09922.9 KXS21255.1 - 2.6e-06 27.3 0.0 4.3e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Cell wall-active antibiotics response 4TMS YvqF DUF1534 PF07551.11 KXS21255.1 - 9.1 6.1 7.9 0.35 10.7 1.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1534) DEAD PF00270.29 KXS21256.1 - 1.8e-27 96.3 0.0 2.8e-27 95.6 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXS21256.1 - 1.8e-17 63.7 0.0 4.1e-17 62.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXS21256.1 - 0.0065 16.5 0.0 0.011 15.8 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit EKLF_TAD1 PF16832.5 KXS21257.1 - 0.11 12.4 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Erythroid krueppel-like transcription factor, transactivation 1 DUF4770 PF15994.5 KXS21258.1 - 0.17 12.1 2.7 0.29 11.4 2.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) Myosin_head PF00063.21 KXS21259.1 - 1.4e-230 767.1 0.0 9.2e-230 764.4 0.0 2.1 1 1 0 1 1 1 1 Myosin head (motor domain) DIL PF01843.19 KXS21259.1 - 1.5e-18 66.9 0.6 4.5e-18 65.4 0.3 2.1 2 0 0 2 2 2 1 DIL domain IQ PF00612.27 KXS21259.1 - 2.2e-05 23.8 1.5 2.2e-05 23.8 1.5 5.1 5 0 0 5 5 5 2 IQ calmodulin-binding motif AAA_22 PF13401.6 KXS21259.1 - 0.025 14.8 2.5 0.069 13.4 0.0 2.8 2 1 0 2 2 2 0 AAA domain F-actin_cap_A PF01267.17 KXS21259.1 - 0.044 13.2 0.0 0.17 11.3 0.0 1.9 2 0 0 2 2 2 0 F-actin capping protein alpha subunit UPF0242 PF06785.11 KXS21259.1 - 0.13 12.4 15.2 0.32 11.1 15.2 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus AAA_16 PF13191.6 KXS21259.1 - 0.15 12.4 0.0 0.15 12.4 0.0 3.0 2 1 0 2 2 2 0 AAA ATPase domain GAS PF13851.6 KXS21259.1 - 0.27 10.6 18.7 0.68 9.2 14.9 2.7 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding PKcGMP_CC PF16808.5 KXS21259.1 - 0.44 10.4 17.3 0.41 10.5 0.5 4.3 5 0 0 5 5 5 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Tropomyosin_1 PF12718.7 KXS21259.1 - 4.9 7.3 22.4 1.6e+02 2.4 22.4 2.5 1 1 0 1 1 1 0 Tropomyosin like MAPEG PF01124.18 KXS21260.1 - 5.1e-17 62.0 0.0 6.3e-17 61.7 0.0 1.1 1 0 0 1 1 1 1 MAPEG family DUF3963 PF13124.6 KXS21260.1 - 0.0085 16.0 0.6 0.019 15.0 0.6 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3963) Maff2 PF12750.7 KXS21260.1 - 0.082 12.7 0.1 0.12 12.2 0.1 1.3 1 0 0 1 1 1 0 Maff2 family LRR_6 PF13516.6 KXS21261.1 - 1.3e-22 77.9 18.9 8.8e-05 22.3 0.2 8.8 9 0 0 9 9 9 5 Leucine Rich repeat LRR_4 PF12799.7 KXS21261.1 - 9e-14 51.4 9.8 0.00062 20.1 0.8 5.2 3 1 3 6 6 6 5 Leucine Rich repeats (2 copies) SPT_ssu-like PF11779.8 KXS21261.1 - 1.1e-13 50.6 0.6 2.1e-13 49.6 0.6 1.4 1 0 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like LRR_1 PF00560.33 KXS21261.1 - 6e-11 41.3 4.6 6.2 7.8 0.0 7.7 7 0 0 7 7 7 3 Leucine Rich Repeat LRR_8 PF13855.6 KXS21261.1 - 5.8e-09 35.6 13.3 0.011 15.5 1.4 5.0 2 1 3 5 5 5 5 Leucine rich repeat MFS_1 PF07690.16 KXS21262.1 - 3.1e-31 108.6 30.4 4.1e-31 108.2 30.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2678 PF10856.8 KXS21262.1 - 0.053 13.5 0.3 22 5.0 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2678) MFS_1 PF07690.16 KXS21263.1 - 1.4e-26 93.3 26.8 2.1e-26 92.7 26.8 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily CitMHS PF03600.16 KXS21263.1 - 5.8 6.0 17.2 5.9 6.0 0.4 3.4 1 1 1 3 3 3 0 Citrate transporter WTF PF03303.13 KXS21263.1 - 8 6.1 8.6 3 7.5 0.7 2.7 3 0 0 3 3 3 0 WTF protein Annexin PF00191.20 KXS21266.1 - 5.1e-31 106.6 0.1 2.1e-10 40.5 0.0 4.5 4 1 1 5 5 5 3 Annexin NMT1 PF09084.11 KXS21267.1 - 2e-05 24.7 0.0 5e-05 23.3 0.0 1.6 2 0 0 2 2 2 1 NMT1/THI5 like NMT1_2 PF13379.6 KXS21267.1 - 0.0046 16.7 0.0 0.0071 16.1 0.0 1.3 1 0 0 1 1 1 1 NMT1-like family NMT1_3 PF16868.5 KXS21267.1 - 0.092 12.1 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 NMT1-like family Pkinase PF00069.25 KXS21268.1 - 1.4e-38 132.8 0.0 2.8e-38 131.8 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS21268.1 - 1.5e-10 40.8 0.0 3.2e-10 39.7 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXS21268.1 - 0.00025 21.1 1.5 0.00051 20.0 0.1 2.1 2 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KXS21268.1 - 0.0012 18.5 0.0 0.002 17.7 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kinase-like PF14531.6 KXS21268.1 - 0.0029 16.9 0.0 0.0052 16.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KXS21268.1 - 0.004 16.5 0.0 0.0075 15.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KXS21268.1 - 0.26 10.2 0.0 0.38 9.6 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain DUF3267 PF11667.8 KXS21269.1 - 0.00096 19.4 1.8 0.0017 18.6 1.8 1.4 1 0 0 1 1 1 1 Putative zincin peptidase SnoaL_2 PF12680.7 KXS21269.1 - 0.05 14.2 0.0 0.088 13.5 0.0 1.4 1 0 0 1 1 1 0 SnoaL-like domain DUF2207 PF09972.9 KXS21269.1 - 0.12 11.1 0.2 0.13 11.1 0.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Aminotran_5 PF00266.19 KXS21271.1 - 1.2e-11 44.2 0.0 0.00032 19.8 0.1 4.0 4 0 0 4 4 4 3 Aminotransferase class-V Muskelin_N PF06588.11 KXS21272.1 - 1.6e-51 175.0 0.0 1.2e-32 113.4 0.1 2.1 2 0 0 2 2 2 2 Muskelin N-terminus Kelch_4 PF13418.6 KXS21272.1 - 8.9e-14 51.2 12.0 0.0043 17.0 0.0 7.1 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_5 PF13854.6 KXS21272.1 - 6.9e-10 38.7 10.4 0.0002 21.2 0.1 6.3 6 0 0 6 6 6 2 Kelch motif Kelch_6 PF13964.6 KXS21272.1 - 2.7e-09 37.0 4.0 0.0012 19.1 0.0 5.5 5 1 0 5 5 5 3 Kelch motif Kelch_3 PF13415.6 KXS21272.1 - 2.6e-07 30.8 25.3 0.0026 18.0 0.4 6.5 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_1 PF01344.25 KXS21272.1 - 4.8e-05 22.8 10.0 0.38 10.4 0.8 5.1 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.15 KXS21272.1 - 0.012 15.6 13.7 0.47 10.5 0.1 5.2 5 0 0 5 5 5 0 Kelch motif F5_F8_type_C PF00754.25 KXS21272.1 - 0.08 13.1 0.4 0.18 11.9 0.0 1.7 2 0 0 2 2 2 0 F5/8 type C domain Cyclin_N PF00134.23 KXS21275.1 - 0.00057 19.6 0.0 1.3 8.8 0.0 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin PF08613.11 KXS21275.1 - 0.032 14.6 0.0 0.72 10.2 0.0 2.6 2 1 0 2 2 2 0 Cyclin adh_short PF00106.25 KXS21276.1 - 2.1e-38 131.7 0.0 4.2e-38 130.8 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXS21276.1 - 5.7e-27 94.8 0.0 1.1e-26 93.8 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXS21276.1 - 4.3e-09 36.5 0.0 9.4e-09 35.4 0.0 1.5 1 1 0 1 1 1 1 KR domain Sld3_N PF18523.1 KXS21276.1 - 0.12 12.5 0.3 4.3 7.5 0.0 2.2 1 1 1 2 2 2 0 Sld3 N-terminal domain PPR PF01535.20 KXS21277.1 - 0.0031 17.6 0.0 0.65 10.4 0.0 4.4 4 0 0 4 4 4 1 PPR repeat mRNA_stabil PF13929.6 KXS21277.1 - 0.014 14.4 0.0 5.6 5.9 0.0 3.0 3 0 0 3 3 3 0 mRNA stabilisation PPR_2 PF13041.6 KXS21277.1 - 0.064 13.5 0.1 14 6.0 0.0 4.3 4 0 0 4 4 4 0 PPR repeat family PAXIP1_C PF15364.6 KXS21277.1 - 0.13 12.5 0.1 0.3 11.4 0.1 1.5 1 0 0 1 1 1 0 PAXIP1-associated-protein-1 C term PTIP binding protein PPR_3 PF13812.6 KXS21277.1 - 0.14 12.2 0.0 28 4.9 0.0 3.6 3 0 0 3 3 3 0 Pentatricopeptide repeat domain TPR_14 PF13428.6 KXS21277.1 - 1.7 9.6 8.6 0.76 10.8 0.2 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat Glycos_transf_1 PF00534.20 KXS21278.1 - 1.1e-14 54.4 0.0 1.9e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KXS21278.1 - 6.1e-14 52.6 0.0 1.3e-13 51.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF3492 PF11997.8 KXS21278.1 - 1.5e-11 44.6 0.0 3.2e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3492) Abhydrolase_6 PF12697.7 KXS21279.1 - 8.3e-07 29.8 2.1 1.2e-06 29.3 2.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXS21279.1 - 0.0018 17.6 0.0 0.052 12.8 0.0 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 LIP PF03583.14 KXS21279.1 - 0.024 13.9 0.3 0.042 13.2 0.3 1.3 1 0 0 1 1 1 0 Secretory lipase Aa_trans PF01490.18 KXS21281.1 - 1.4e-62 211.7 15.2 3.3e-53 180.9 5.0 2.1 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KXS21281.1 - 0.0025 16.9 3.7 0.0025 16.9 3.7 2.7 3 0 0 3 3 3 2 Tryptophan/tyrosine permease family Asp PF00026.23 KXS21282.1 - 1.1e-66 225.5 0.1 2e-47 162.2 0.0 2.2 2 0 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 KXS21282.1 - 3.1e-12 47.1 0.0 6.7e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 KXS21282.1 - 0.074 12.8 0.0 0.17 11.7 0.0 1.6 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal CBM_1 PF00734.18 KXS21283.1 - 2.8e-10 40.0 9.0 6.4e-10 38.8 9.0 1.7 1 0 0 1 1 1 1 Fungal cellulose binding domain SH3_9 PF14604.6 KXS21283.1 - 2e-05 24.4 0.0 8.4e-05 22.4 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 KXS21283.1 - 0.00071 19.1 0.0 0.0022 17.6 0.0 1.9 1 0 0 1 1 1 1 SH3 domain ATG16 PF08614.11 KXS21283.1 - 0.0029 17.9 3.9 0.0029 17.9 3.9 2.1 3 0 0 3 3 1 1 Autophagy protein 16 (ATG16) Ank_3 PF13606.6 KXS21283.1 - 0.004 17.6 0.0 0.016 15.7 0.0 2.1 1 0 0 1 1 1 1 Ankyrin repeat Ank PF00023.30 KXS21283.1 - 0.01 16.3 0.7 0.072 13.6 0.0 2.6 2 0 0 2 2 2 0 Ankyrin repeat Nsp1_C PF05064.13 KXS21283.1 - 0.013 15.3 0.6 0.024 14.4 0.6 1.3 1 0 0 1 1 1 0 Nsp1-like C-terminal region PI3K_P85_iSH2 PF16454.5 KXS21283.1 - 0.044 13.4 1.7 0.069 12.7 1.7 1.2 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain APG6_N PF17675.1 KXS21283.1 - 0.069 13.7 6.0 0.11 13.0 6.0 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF4472 PF14739.6 KXS21283.1 - 0.087 13.6 4.2 0.15 12.8 4.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4472) DivIC PF04977.15 KXS21283.1 - 0.14 12.0 2.1 0.17 11.7 0.9 1.8 1 1 0 1 1 1 0 Septum formation initiator Ank_2 PF12796.7 KXS21283.1 - 0.14 12.7 0.0 0.46 11.1 0.0 1.9 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) YabA PF06156.13 KXS21283.1 - 0.25 12.0 0.7 0.45 11.2 0.7 1.4 1 0 0 1 1 1 0 Initiation control protein YabA TolA_bind_tri PF16331.5 KXS21283.1 - 0.31 11.1 2.6 0.63 10.2 2.6 1.5 1 0 0 1 1 1 0 TolA binding protein trimerisation DUF3450 PF11932.8 KXS21283.1 - 0.43 9.8 4.3 0.7 9.1 4.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) ABC_tran_CTD PF16326.5 KXS21283.1 - 0.53 10.6 2.9 1.1 9.6 2.9 1.5 1 0 0 1 1 1 0 ABC transporter C-terminal domain SlyX PF04102.12 KXS21283.1 - 0.62 10.7 4.8 0.66 10.6 1.8 2.3 1 1 1 2 2 2 0 SlyX DUF2968 PF11180.8 KXS21283.1 - 0.83 9.3 4.7 1.4 8.5 4.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) GAS PF13851.6 KXS21283.1 - 2.6 7.3 7.0 3.8 6.8 7.0 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Jnk-SapK_ap_N PF09744.9 KXS21283.1 - 4.9 7.4 6.6 3.9 7.7 5.2 1.5 2 0 0 2 2 1 0 JNK_SAPK-associated protein-1 EHN PF06441.12 KXS21284.1 - 9.8e-32 109.5 0.0 2.2e-31 108.4 0.0 1.6 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KXS21284.1 - 2.2e-13 50.5 0.1 2.5e-12 47.0 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXS21284.1 - 0.011 16.3 0.7 0.022 15.3 0.1 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase family PPR_2 PF13041.6 KXS21285.1 - 5.1e-14 52.2 0.1 1.1e-05 25.5 0.0 3.8 3 1 1 4 4 4 3 PPR repeat family PPR_3 PF13812.6 KXS21285.1 - 6.8e-08 32.5 0.0 0.00019 21.4 0.0 3.4 2 1 2 4 4 4 2 Pentatricopeptide repeat domain PPR PF01535.20 KXS21285.1 - 5.5e-06 26.3 4.1 0.078 13.3 0.0 5.1 6 1 0 6 6 6 2 PPR repeat PPR_long PF17177.4 KXS21285.1 - 0.0024 17.3 0.0 0.014 14.8 0.0 2.0 1 1 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP ATP13 PF12921.7 KXS21285.1 - 0.0025 17.7 0.0 0.074 12.9 0.0 2.6 2 0 0 2 2 2 1 Mitochondrial ATPase expression PPR_1 PF12854.7 KXS21285.1 - 0.025 14.3 0.2 16 5.3 0.0 3.2 3 0 0 3 3 3 0 PPR repeat PPR PF01535.20 KXS21286.1 - 0.076 13.3 0.0 12 6.4 0.0 2.4 2 0 0 2 2 2 0 PPR repeat Peptidase_M32 PF02074.15 KXS21287.1 - 7.1e-156 519.8 0.0 8e-156 519.6 0.0 1.0 1 0 0 1 1 1 1 Carboxypeptidase Taq (M32) metallopeptidase LRR_4 PF12799.7 KXS21289.1 - 0.00014 22.2 2.4 0.00074 19.9 2.4 2.1 1 1 0 1 1 1 1 Leucine Rich repeats (2 copies) SH3_9 PF14604.6 KXS21289.1 - 0.00029 20.6 0.1 0.00059 19.6 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXS21289.1 - 0.031 13.9 0.0 0.06 13.0 0.0 1.4 1 0 0 1 1 1 0 SH3 domain TMEM154 PF15102.6 KXS21289.1 - 0.22 11.4 0.5 0.42 10.5 0.0 1.7 2 0 0 2 2 2 0 TMEM154 protein family LRR_8 PF13855.6 KXS21289.1 - 0.45 10.3 3.9 1.7 8.5 1.2 2.2 1 1 1 2 2 2 0 Leucine rich repeat Dus PF01207.17 KXS21291.1 - 1.7e-61 208.1 0.5 3.1e-61 207.2 0.5 1.4 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) DHO_dh PF01180.21 KXS21291.1 - 0.041 13.1 0.0 0.054 12.7 0.0 1.2 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase Pkinase PF00069.25 KXS21292.1 - 8.5e-69 231.8 0.0 9.9e-69 231.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS21292.1 - 6e-35 120.8 0.0 7.8e-35 120.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXS21292.1 - 0.042 13.2 0.0 0.068 12.5 0.0 1.5 1 0 0 1 1 1 0 Kinase-like HABP4_PAI-RBP1 PF04774.15 KXS21293.1 - 0.0002 22.2 0.7 0.00036 21.4 0.7 1.3 1 1 0 1 1 1 1 Hyaluronan / mRNA binding family CALM_bind PF16025.5 KXS21294.1 - 0.19 12.2 1.1 0.69 10.4 0.0 2.3 2 1 1 3 3 3 0 Calcium-dependent calmodulin binding SlyX PF04102.12 KXS21294.1 - 1.4 9.6 3.9 0.79 10.4 0.4 2.3 2 1 1 3 3 3 0 SlyX IGR PF09597.10 KXS21295.1 - 5.9e-24 83.9 0.0 1.1e-23 83.1 0.0 1.5 1 0 0 1 1 1 1 IGR protein motif LRR_4 PF12799.7 KXS21296.1 - 3.3e-09 36.9 16.1 0.00086 19.7 0.4 5.6 3 2 3 6 6 6 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXS21296.1 - 4.8e-08 32.7 12.6 0.0007 19.3 0.9 4.7 3 1 1 4 4 4 4 Leucine rich repeat LRR_1 PF00560.33 KXS21296.1 - 0.04 14.5 15.2 30 5.7 0.0 7.0 6 1 0 6 6 6 0 Leucine Rich Repeat LRR_6 PF13516.6 KXS21296.1 - 0.22 11.6 8.4 9.6 6.6 0.0 5.3 6 0 0 6 6 6 0 Leucine Rich repeat LRR_4 PF12799.7 KXS21297.1 - 1.6e-13 50.5 24.8 0.00076 19.8 0.1 6.2 5 1 1 6 6 6 5 Leucine Rich repeats (2 copies) SH3_1 PF00018.28 KXS21297.1 - 3.9e-07 29.6 0.0 7.5e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 SH3 domain LRR_8 PF13855.6 KXS21297.1 - 1.4e-06 28.0 23.0 0.006 16.3 2.6 5.5 3 2 3 6 6 6 4 Leucine rich repeat SH3_9 PF14604.6 KXS21297.1 - 0.0045 16.8 0.0 0.012 15.5 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain LRR_4 PF12799.7 KXS21298.1 - 3.2e-15 56.0 25.0 0.0011 19.3 1.0 6.4 5 1 1 6 6 6 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXS21298.1 - 1.5e-09 37.4 22.1 0.00033 20.4 0.1 5.4 4 1 0 5 5 5 4 Leucine rich repeat SH3_1 PF00018.28 KXS21298.1 - 2.8e-06 26.8 0.0 5.2e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KXS21298.1 - 0.0049 16.7 0.0 0.013 15.4 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain Podoplanin PF05808.11 KXS21298.1 - 0.018 15.2 0.3 0.037 14.1 0.3 1.5 1 0 0 1 1 1 0 Podoplanin Amnionless PF14828.6 KXS21298.1 - 0.043 12.7 0.0 0.065 12.1 0.0 1.2 1 0 0 1 1 1 0 Amnionless LRR_1 PF00560.33 KXS21298.1 - 7.2 7.6 13.9 1.2e+02 3.9 0.0 6.4 6 2 0 6 6 6 0 Leucine Rich Repeat adh_short PF00106.25 KXS21299.1 - 4.3e-27 94.8 0.0 6.2e-27 94.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXS21299.1 - 9.1e-17 61.4 0.0 1.3e-16 60.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXS21299.1 - 0.0027 17.6 0.0 0.0046 16.9 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXS21299.1 - 0.1 12.1 0.0 0.38 10.2 0.0 1.9 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Latexin PF06907.12 KXS21299.1 - 0.17 11.4 0.0 0.26 10.8 0.0 1.2 1 0 0 1 1 1 0 Latexin MTS PF05175.14 KXS21300.1 - 0.00029 20.4 0.0 0.00083 18.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase small domain PrmC_N PF17827.1 KXS21300.1 - 0.0086 16.6 0.1 0.053 14.1 0.1 2.2 1 1 0 1 1 1 1 PrmC N-terminal domain Methyltransf_25 PF13649.6 KXS21300.1 - 0.012 16.2 0.0 0.025 15.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 KXS21300.1 - 0.023 14.5 0.0 0.037 13.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain ATP-synt_Eps PF04627.13 KXS21301.1 - 4e-18 65.1 0.8 4.6e-18 64.9 0.8 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain DUF2011 PF09428.10 KXS21302.1 - 0.017 15.4 0.2 0.087 13.1 0.2 2.3 1 1 0 1 1 1 0 Fungal protein of unknown function (DUF2011) Coilin_N PF15862.5 KXS21302.1 - 7.9 6.3 10.5 0.25 11.1 2.7 2.3 3 0 0 3 3 3 0 Coilin N-terminus Ank_2 PF12796.7 KXS21304.1 - 6.3e-33 113.2 0.0 3.2e-11 43.7 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXS21304.1 - 7.7e-31 105.8 1.6 6.6e-10 39.0 0.0 5.4 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXS21304.1 - 1.5e-29 102.0 0.1 1.4e-07 31.9 0.0 4.8 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXS21304.1 - 5.5e-25 84.7 0.4 0.00041 20.6 0.0 6.1 7 0 0 7 7 7 5 Ankyrin repeat Ank PF00023.30 KXS21304.1 - 4.9e-23 80.5 0.8 0.00023 21.5 0.0 6.1 6 0 0 6 6 6 5 Ankyrin repeat DUF1843 PF08898.10 KXS21304.1 - 0.091 13.3 0.2 7.5 7.1 0.1 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) Exo_endo_phos PF03372.23 KXS21305.1 - 7.9e-08 32.1 0.0 7.8e-07 28.8 0.0 2.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LSPR PF06049.12 KXS21305.1 - 0.084 12.7 1.1 1.5 9.0 0.3 2.9 2 0 0 2 2 2 0 Coagulation Factor V LSPD Repeat Ank_2 PF12796.7 KXS21307.1 - 1.2e-23 83.5 0.0 2.1e-14 53.9 0.0 4.4 4 0 0 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXS21307.1 - 5e-18 64.9 1.5 9.2e-05 22.6 0.2 6.5 4 1 3 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXS21307.1 - 6.4e-18 63.0 1.1 0.0012 19.2 0.0 7.8 8 0 0 8 8 8 4 Ankyrin repeat Ank PF00023.30 KXS21307.1 - 1.2e-11 44.5 8.8 0.086 13.3 0.0 6.9 7 0 0 7 7 7 4 Ankyrin repeat Ank_4 PF13637.6 KXS21307.1 - 2.5e-11 43.9 0.2 1.8e-07 31.6 0.1 5.4 5 2 2 7 7 7 1 Ankyrin repeats (many copies) Beta-lactamase PF00144.24 KXS21308.1 - 4.5e-41 141.2 3.2 1e-40 140.0 3.2 1.5 1 1 0 1 1 1 1 Beta-lactamase MFS_1 PF07690.16 KXS21310.1 - 1.5e-28 99.7 28.0 2.3e-28 99.2 28.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Profilin PF00235.19 KXS21311.1 - 7.9e-49 165.2 0.2 8.8e-49 165.0 0.2 1.0 1 0 0 1 1 1 1 Profilin MgtE PF01769.16 KXS21312.1 - 2.1e-15 57.2 3.4 2.1e-15 57.2 3.4 2.6 3 0 0 3 3 3 1 Divalent cation transporter Cwf_Cwc_15 PF04889.12 KXS21312.1 - 0.011 15.5 8.2 0.016 14.9 8.2 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF4598 PF15370.6 KXS21312.1 - 0.087 13.3 2.7 0.18 12.3 2.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4598) ABC_membrane_3 PF13748.6 KXS21312.1 - 1.8 7.7 8.6 0.053 12.7 1.6 1.9 2 0 0 2 2 2 0 ABC transporter transmembrane region tRNA-synt_1c PF00749.21 KXS21313.1 - 3.7e-81 272.4 0.0 2.9e-79 266.2 0.0 2.8 1 1 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain ABATE PF07336.11 KXS21313.1 - 0.034 14.8 3.9 0.039 14.6 0.1 2.8 3 0 0 3 3 3 0 Putative stress-induced transcription regulator DUF1697 PF08002.11 KXS21314.1 - 7.8e-22 78.2 0.0 1.2e-21 77.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1697) Ski_Sno PF02437.17 KXS21314.1 - 0.16 11.7 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 SKI/SNO/DAC family VHS PF00790.19 KXS21315.1 - 2.4e-40 137.7 0.0 4.1e-40 136.9 0.0 1.4 1 0 0 1 1 1 1 VHS domain Alpha_adaptinC2 PF02883.20 KXS21315.1 - 4.8e-25 88.0 0.0 1e-24 87.0 0.0 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain GAT PF03127.14 KXS21315.1 - 4.2e-09 36.6 0.0 2e-08 34.4 0.0 2.2 2 0 0 2 2 2 1 GAT domain ISG65-75 PF11727.8 KXS21315.1 - 0.081 12.1 0.4 0.13 11.5 0.4 1.3 1 0 0 1 1 1 0 Invariant surface glycoprotein SET PF00856.28 KXS21316.1 - 3e-13 50.5 0.1 6.7e-11 42.9 0.0 2.1 1 1 1 2 2 2 2 SET domain RINT1_TIP1 PF04437.13 KXS21317.1 - 3.8e-78 263.6 0.0 5.1e-78 263.2 0.0 1.2 1 0 0 1 1 1 1 RINT-1 / TIP-1 family Nairo_nucleo PF02477.15 KXS21317.1 - 0.2 10.4 0.2 0.33 9.7 0.2 1.2 1 0 0 1 1 1 0 Nucleocapsid N protein EF-hand_1 PF00036.32 KXS21318.1 - 5.2e-43 141.4 13.6 1.5e-10 39.9 1.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KXS21318.1 - 1.4e-36 124.8 3.2 7.5e-19 68.0 1.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KXS21318.1 - 1.2e-31 105.9 6.9 1.3e-09 37.2 0.1 4.4 4 1 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 KXS21318.1 - 2.4e-31 107.4 12.2 8.3e-15 54.4 0.7 4.1 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 KXS21318.1 - 5.6e-28 95.2 9.7 9.6e-07 28.0 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 KXS21318.1 - 2.7e-16 59.7 0.2 2.3e-09 37.4 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 KXS21318.1 - 2.1e-10 40.5 0.9 3.9e-05 23.5 0.2 2.2 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 KXS21318.1 - 9.3e-09 35.6 0.0 0.00095 19.5 0.1 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 KXS21318.1 - 5.1e-07 30.5 0.0 0.0002 22.2 0.0 2.1 1 1 1 2 2 2 1 EF-hand domain UPF0154 PF03672.13 KXS21318.1 - 1.1e-05 25.3 1.5 0.042 13.9 0.0 3.6 3 1 1 4 4 4 2 Uncharacterised protein family (UPF0154) Dockerin_1 PF00404.18 KXS21318.1 - 6.3e-05 23.1 4.4 0.016 15.4 0.3 3.1 1 1 2 3 3 3 2 Dockerin type I domain EFhand_Ca_insen PF08726.10 KXS21318.1 - 0.00011 22.2 1.5 0.0005 20.1 0.2 2.3 2 2 0 2 2 2 1 Ca2+ insensitive EF hand DUF3349 PF11829.8 KXS21318.1 - 0.00072 20.3 0.4 1.2 10.0 0.0 2.9 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) DUF1103 PF06513.11 KXS21318.1 - 0.00081 19.1 2.8 0.00094 18.9 2.8 1.2 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) DUF4497 PF14924.6 KXS21318.1 - 0.00083 19.8 0.0 0.43 11.1 0.0 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF4497) Caleosin PF05042.13 KXS21318.1 - 0.001 19.0 1.5 0.5 10.3 0.0 3.5 1 1 3 4 4 4 1 Caleosin related protein TerB PF05099.13 KXS21318.1 - 0.0011 18.9 0.4 0.61 10.0 0.0 2.3 1 1 1 2 2 2 2 Tellurite resistance protein TerB RNA_pol_Rpb4 PF03874.16 KXS21318.1 - 0.0019 18.5 0.3 1.4 9.3 0.1 2.7 3 0 0 3 3 3 1 RNA polymerase Rpb4 Poly_export PF02563.16 KXS21318.1 - 0.0023 18.1 0.1 0.43 10.8 0.0 3.1 1 1 1 2 2 2 1 Polysaccharide biosynthesis/export protein DUF5580 PF17743.1 KXS21318.1 - 0.0071 14.9 0.0 0.0071 14.9 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5580) MotA_activ PF09114.10 KXS21318.1 - 0.0078 16.3 0.5 0.12 12.6 0.1 2.3 1 1 0 2 2 2 1 Transcription factor MotA, activation domain SurA_N_2 PF13623.6 KXS21318.1 - 0.011 15.6 0.9 0.57 10.1 0.2 2.3 1 1 1 2 2 2 0 SurA N-terminal domain dCache_2 PF08269.11 KXS21318.1 - 0.021 14.0 0.2 2 7.5 0.1 2.3 1 1 1 2 2 2 0 Cache domain EF-hand_14 PF17959.1 KXS21318.1 - 0.033 14.5 0.2 9.1 6.7 0.0 2.5 1 1 1 2 2 2 0 EF-hand domain DUF2267 PF10025.9 KXS21318.1 - 0.034 14.4 0.0 0.19 12.0 0.0 2.0 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2267) Spore_III_AB PF09548.10 KXS21318.1 - 0.11 12.6 0.5 0.23 11.6 0.5 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) TetR_C_7 PF14246.6 KXS21318.1 - 0.12 12.4 0.0 6.7 6.8 0.0 2.6 2 1 1 3 3 3 0 AefR-like transcriptional repressor, C-terminal domain RuvA_C PF07499.13 KXS21318.1 - 0.14 12.7 0.1 13 6.4 0.0 3.0 3 0 0 3 3 3 0 RuvA, C-terminal domain SapB_1 PF05184.15 KXS21318.1 - 0.18 11.9 2.8 27 4.9 0.0 3.6 4 0 0 4 4 4 0 Saposin-like type B, region 1 LRR_6 PF13516.6 KXS21319.1 - 8.1e-13 47.3 16.4 0.0038 17.2 0.1 5.2 5 0 0 5 5 5 4 Leucine Rich repeat LRR_4 PF12799.7 KXS21319.1 - 2.9e-06 27.5 0.6 0.0013 19.1 0.2 3.8 2 1 3 5 5 5 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KXS21319.1 - 0.00017 21.6 2.5 40 5.3 0.0 5.6 5 1 0 5 5 5 0 Leucine Rich Repeat LRR_8 PF13855.6 KXS21319.1 - 0.0019 18.0 6.5 0.0067 16.2 1.0 3.6 2 1 1 3 3 3 1 Leucine rich repeat Pkinase_fungal PF17667.1 KXS21319.1 - 0.44 9.3 2.4 1 8.0 2.4 1.5 1 1 0 1 1 1 0 Fungal protein kinase SWI-SNF_Ssr4 PF08549.10 KXS21319.1 - 1.2 7.7 8.3 2 7.0 8.3 1.3 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) WD40 PF00400.32 KXS21320.1 - 2.5e-14 53.4 10.1 6e-05 23.7 0.3 4.7 4 0 0 4 4 4 3 WD domain, G-beta repeat Nucleoporin_N PF08801.11 KXS21320.1 - 0.0021 16.9 0.0 0.023 13.4 0.0 2.2 2 0 0 2 2 2 1 Nup133 N terminal like SMC_N PF02463.19 KXS21321.1 - 1.9e-58 197.5 9.3 4.8e-57 192.9 9.3 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KXS21321.1 - 2.1e-26 92.5 0.0 7.1e-26 90.8 0.0 2.0 2 0 0 2 2 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 KXS21321.1 - 1.6e-12 47.9 11.5 3.3e-07 30.4 0.0 4.1 4 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KXS21321.1 - 1.9e-07 30.7 0.0 3.9e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ATG16 PF08614.11 KXS21321.1 - 0.0026 18.0 21.1 0.0026 18.0 21.1 6.5 5 2 1 6 6 5 2 Autophagy protein 16 (ATG16) KxDL PF10241.9 KXS21321.1 - 0.0035 17.6 4.2 0.0035 17.6 4.2 7.6 6 3 3 9 9 9 2 Uncharacterized conserved protein DHR10 PF18595.1 KXS21321.1 - 0.0039 17.2 10.5 0.0039 17.2 10.5 10.4 6 2 6 12 12 11 2 Designed helical repeat protein 10 domain TMF_DNA_bd PF12329.8 KXS21321.1 - 0.0054 16.7 11.5 0.0054 16.7 11.5 11.3 7 3 2 11 11 11 1 TATA element modulatory factor 1 DNA binding UPF0242 PF06785.11 KXS21321.1 - 0.006 16.7 3.0 0.006 16.7 3.0 6.4 4 1 3 7 7 6 1 Uncharacterised protein family (UPF0242) N-terminus ADIP PF11559.8 KXS21321.1 - 0.0078 16.3 8.4 0.0078 16.3 8.4 9.1 5 3 3 9 9 9 2 Afadin- and alpha -actinin-Binding SbcCD_C PF13558.6 KXS21321.1 - 0.008 16.4 0.0 0.21 11.8 0.0 2.8 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Cir_Bir_Yir PF06022.11 KXS21321.1 - 0.0097 15.4 0.2 0.0097 15.4 0.2 2.6 3 0 0 3 3 3 1 Plasmodium variant antigen protein Cir/Yir/Bir OmpH PF03938.14 KXS21321.1 - 0.014 15.7 2.3 0.014 15.7 2.3 8.9 3 2 4 7 7 6 0 Outer membrane protein (OmpH-like) AAA_13 PF13166.6 KXS21321.1 - 0.024 13.3 0.2 0.024 13.3 0.2 6.6 4 2 3 7 7 6 0 AAA domain AAA_15 PF13175.6 KXS21321.1 - 0.044 13.5 65.9 0.054 13.2 30.0 5.5 3 2 0 3 3 2 0 AAA ATPase domain DUF1664 PF07889.12 KXS21321.1 - 0.055 13.5 51.1 0.036 14.1 7.2 8.1 5 4 1 7 7 7 0 Protein of unknown function (DUF1664) ABC_tran PF00005.27 KXS21321.1 - 0.13 12.8 0.0 0.13 12.8 0.0 6.8 4 2 0 6 6 6 0 ABC transporter Baculo_PEP_C PF04513.12 KXS21321.1 - 0.33 11.0 26.8 0.088 12.9 2.0 5.7 5 2 0 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus Acetyltransf_16 PF05301.11 KXS21322.1 - 5.7e-41 140.2 0.0 1.6e-31 109.4 0.0 2.1 1 1 1 2 2 2 2 GNAT acetyltransferase, Mec-17 Arabinose_bd PF12625.7 KXS21322.1 - 0.022 14.9 0.4 0.045 13.8 0.4 1.5 1 0 0 1 1 1 0 Arabinose-binding domain of AraC transcription regulator, N-term Acetyltransf_7 PF13508.7 KXS21322.1 - 0.027 14.9 0.0 0.046 14.1 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXS21322.1 - 0.035 14.4 0.0 0.059 13.6 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXS21322.1 - 0.093 12.7 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Rad21_Rec8_N PF04825.13 KXS21323.1 - 1.2e-31 109.1 0.0 2.9e-31 107.9 0.0 1.6 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 KXS21323.1 - 1.3e-07 30.8 0.0 2.4e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein Ras PF00071.22 KXS21324.1 - 1.9e-34 118.6 0.2 2.2e-34 118.4 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXS21324.1 - 1.3e-25 90.0 0.1 1.9e-25 89.4 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXS21324.1 - 3e-08 33.3 0.1 3.8e-08 33.0 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KXS21324.1 - 2.6e-07 30.2 0.3 3.4e-07 29.9 0.3 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DLIC PF05783.11 KXS21324.1 - 0.0014 17.6 0.8 0.41 9.4 0.0 2.0 1 1 0 2 2 2 2 Dynein light intermediate chain (DLIC) TniB PF05621.11 KXS21324.1 - 0.02 14.3 0.0 1.6 8.1 0.0 2.2 2 0 0 2 2 2 0 Bacterial TniB protein SRPRB PF09439.10 KXS21324.1 - 0.051 13.0 0.0 0.063 12.7 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KXS21324.1 - 0.074 13.1 0.0 0.12 12.4 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase G-alpha PF00503.20 KXS21324.1 - 0.08 12.1 1.5 0.15 11.2 0.2 2.1 1 1 1 2 2 2 0 G-protein alpha subunit Herpes_DNAp_acc PF04929.12 KXS21325.1 - 0.12 11.4 2.1 0.2 10.6 2.1 1.3 1 0 0 1 1 1 0 Herpes DNA replication accessory factor IQ PF00612.27 KXS21325.1 - 1.9 8.5 16.8 0.066 13.0 1.3 4.3 3 0 0 3 3 3 0 IQ calmodulin-binding motif Kelch_5 PF13854.6 KXS21327.1 - 2.2e-09 37.1 0.0 0.0055 16.7 0.0 3.9 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.6 KXS21327.1 - 1.3e-06 28.3 1.9 0.011 15.7 0.0 3.2 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_3 PF13415.6 KXS21327.1 - 1.7e-05 25.0 7.9 0.0031 17.8 0.2 4.2 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_6 PF13964.6 KXS21327.1 - 3.8e-05 23.8 0.1 0.028 14.7 0.0 3.3 2 0 0 2 2 2 2 Kelch motif Kelch_2 PF07646.15 KXS21327.1 - 0.049 13.6 0.0 2.8 8.1 0.0 2.8 2 0 0 2 2 2 0 Kelch motif Nup_retrotrp_bd PF10599.9 KXS21327.1 - 3.2 8.5 6.3 11 6.8 0.4 2.8 2 1 0 2 2 2 0 Retro-transposon transporting motif SH3_1 PF00018.28 KXS21328.1 - 6.6e-10 38.4 0.0 7.7e-09 35.0 0.0 2.5 2 1 1 3 3 3 1 SH3 domain SH3_9 PF14604.6 KXS21328.1 - 5.4e-07 29.4 0.0 1.1e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KXS21328.1 - 0.016 14.9 0.0 0.045 13.4 0.0 1.7 2 0 0 2 2 2 0 Variant SH3 domain RAMP4 PF06624.12 KXS21330.1 - 2.2e-18 66.1 0.0 2.4e-18 66.0 0.0 1.0 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 Synaptobrevin PF00957.21 KXS21331.1 - 5.6e-12 45.3 0.0 9.1e-12 44.6 0.0 1.4 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 KXS21331.1 - 2.6e-07 30.6 0.0 4.4e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain RNB PF00773.19 KXS21332.1 - 3.4e-99 332.3 0.0 4.5e-99 331.9 0.0 1.2 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 KXS21332.1 - 2.3e-19 69.2 0.0 4.8e-19 68.2 0.0 1.6 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Rrp44_S1 PF17215.3 KXS21332.1 - 1.8e-13 50.2 0.0 3.9e-13 49.2 0.0 1.6 1 0 0 1 1 1 1 S1 domain PIN_4 PF13638.6 KXS21332.1 - 1.8e-13 50.9 0.0 3.7e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 PIN domain Rrp44_CSD1 PF17216.3 KXS21332.1 - 2.2e-11 43.7 0.0 4.4e-11 42.7 0.0 1.5 1 0 0 1 1 1 1 Rrp44-like cold shock domain CSD2 PF17876.1 KXS21332.1 - 5.2e-07 29.7 0.1 5.8e-06 26.4 0.0 2.9 4 0 0 4 4 4 1 Cold shock domain Dis3l2_C_term PF17877.1 KXS21332.1 - 0.023 15.0 0.0 0.063 13.6 0.0 1.8 1 0 0 1 1 1 0 DIS3-like exonuclease 2 C terminal OB_RNB PF08206.11 KXS21332.1 - 0.13 12.0 0.1 0.53 10.0 0.0 2.1 1 1 0 1 1 1 0 Ribonuclease B OB domain SH3_9 PF14604.6 KXS21333.1 - 4.5e-37 125.7 1.0 6e-12 45.2 0.0 3.6 3 0 0 3 3 3 3 Variant SH3 domain SH3_1 PF00018.28 KXS21333.1 - 1.6e-36 123.7 1.5 2.6e-11 42.9 0.1 3.6 3 0 0 3 3 3 3 SH3 domain SH3_2 PF07653.17 KXS21333.1 - 2.4e-30 104.0 0.3 2.2e-13 49.7 0.0 3.5 3 0 0 3 3 3 3 Variant SH3 domain FCH PF00611.23 KXS21333.1 - 1.8e-10 40.9 4.7 2.3e-09 37.4 0.0 3.6 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain DUF3104 PF11302.8 KXS21333.1 - 0.023 14.5 0.4 1 9.2 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3104) Acyl-CoA_dh_1 PF00441.24 KXS21333.1 - 0.092 12.9 0.5 0.24 11.6 0.5 1.7 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain Adhesin_P1_N PF18652.1 KXS21333.1 - 2.2 8.3 6.1 0.31 11.1 0.3 2.6 2 0 0 2 2 2 0 Adhesin P1 N-terminal domain DUF3347 PF11827.8 KXS21335.1 - 0.12 12.6 3.8 0.12 12.5 2.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3347) Atg14 PF10186.9 KXS21337.1 - 0.034 13.2 0.2 0.048 12.7 0.2 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 NRBF2 PF08961.10 KXS21337.1 - 0.036 13.7 0.2 0.13 11.8 0.2 1.9 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator ZapB PF06005.12 KXS21337.1 - 0.15 12.5 2.7 0.48 10.9 2.7 1.9 1 1 0 1 1 1 0 Cell division protein ZapB TMF_TATA_bd PF12325.8 KXS21337.1 - 0.34 11.2 4.6 0.85 9.9 4.6 1.7 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding RWD PF05773.22 KXS21338.1 - 1e-18 67.7 0.0 1.9e-18 66.8 0.0 1.5 1 0 0 1 1 1 1 RWD domain IBR PF01485.21 KXS21338.1 - 2.1e-17 63.1 34.6 1.3e-10 41.4 8.7 3.4 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 KXS21338.1 - 0.00035 20.8 7.2 0.00035 20.8 7.2 4.5 3 2 1 4 4 4 1 Ring finger domain zf-C3HC4_2 PF13923.6 KXS21338.1 - 0.00093 19.0 4.8 0.00093 19.0 4.8 4.8 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXS21338.1 - 0.0023 17.8 2.9 0.0023 17.8 2.9 4.7 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXS21338.1 - 0.0027 17.6 4.0 0.0027 17.6 4.0 4.1 3 1 1 4 4 4 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KXS21338.1 - 0.0076 16.3 3.0 0.0076 16.3 3.0 3.7 3 0 0 3 3 3 1 RING-type zinc-finger zf-piccolo PF05715.13 KXS21338.1 - 0.02 15.0 5.9 0.02 15.0 5.9 3.3 3 0 0 3 3 3 0 Piccolo Zn-finger zf-RING_11 PF17123.5 KXS21338.1 - 0.93 9.3 14.1 0.2 11.4 7.0 3.1 3 0 0 3 3 3 0 RING-like zinc finger Snf7 PF03357.21 KXS21339.1 - 2.4e-38 131.4 26.9 3.4e-38 131.0 26.9 1.2 1 0 0 1 1 1 1 Snf7 Tub_N PF16322.5 KXS21339.1 - 0.024 15.1 4.0 0.033 14.6 4.0 1.3 1 0 0 1 1 1 0 Tubby N-terminal HTH_6 PF01418.17 KXS21339.1 - 0.057 13.4 0.3 0.15 12.0 0.3 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family DUF5352 PF17303.2 KXS21339.1 - 0.26 11.1 4.6 0.32 10.9 0.4 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5352) DDE_Tnp_IS240 PF13610.6 KXS21339.1 - 1.6 9.0 6.7 0.42 10.8 2.5 2.0 1 1 1 2 2 2 0 DDE domain FapA PF03961.13 KXS21339.1 - 7.2 5.1 11.8 7.6 5.0 10.8 1.4 1 1 1 2 2 2 0 Flagellar Assembly Protein A DFRP_C PF16543.5 KXS21340.1 - 5.6e-24 84.4 5.7 5.6e-24 84.4 5.7 4.8 4 1 1 5 5 5 1 DRG Family Regulatory Proteins, Tma46 zf-CCCH PF00642.24 KXS21340.1 - 2e-06 27.6 2.0 2e-06 27.6 2.0 2.3 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KXS21340.1 - 4.4e-06 26.3 10.6 0.0004 20.1 1.9 3.0 3 0 0 3 3 3 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KXS21340.1 - 8.1e-05 22.5 7.4 8.1e-05 22.5 7.4 3.0 3 0 0 3 3 3 1 Zinc finger domain Torus PF16131.5 KXS21340.1 - 0.0026 18.4 21.0 0.0036 18.0 6.9 4.2 1 1 1 3 3 3 2 Torus domain zf-CCCH_3 PF15663.5 KXS21340.1 - 0.0062 16.7 0.2 0.0062 16.7 0.2 2.9 3 0 0 3 3 3 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 KXS21340.1 - 0.03 14.8 13.4 0.079 13.5 4.2 2.9 2 1 0 2 2 2 0 RNA-binding, Nab2-type zinc finger ComA PF02679.15 KXS21340.1 - 0.078 12.4 3.3 0.15 11.5 3.3 1.4 1 0 0 1 1 1 0 (2R)-phospho-3-sulfolactate synthase (ComA) Mito_carr PF00153.27 KXS21341.1 - 5.4e-41 138.4 7.0 4.5e-15 55.3 0.7 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein MARVEL PF01284.23 KXS21342.1 - 5.2e-07 29.8 9.3 8e-07 29.2 9.3 1.3 1 1 0 1 1 1 1 Membrane-associating domain Cyt-b5 PF00173.28 KXS21343.1 - 6.4e-10 39.0 0.1 2e-09 37.4 0.1 1.8 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain adh_short PF00106.25 KXS21346.1 - 3.6e-35 121.2 0.2 4.6e-35 120.8 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXS21346.1 - 1e-24 87.4 0.1 1.4e-24 86.9 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXS21346.1 - 0.00033 20.6 0.0 0.00052 20.0 0.0 1.3 1 0 0 1 1 1 1 KR domain 2-Hacid_dh_C PF02826.19 KXS21346.1 - 0.089 12.1 0.0 0.19 11.0 0.0 1.7 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F-box-like PF12937.7 KXS21347.1 - 4.3e-06 26.5 5.6 4.6e-06 26.4 0.9 2.8 2 0 0 2 2 2 1 F-box-like Pkinase PF00069.25 KXS21348.1 - 1.2e-57 195.3 0.0 1.5e-57 194.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS21348.1 - 7e-22 77.9 0.0 1.2e-21 77.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXS21348.1 - 7.6e-07 28.7 0.0 9.5e-06 25.1 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KXS21348.1 - 8.7e-05 21.5 0.0 0.00015 20.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KXS21348.1 - 0.0033 17.4 0.0 0.0074 16.2 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KXS21348.1 - 0.012 15.0 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Cyt-b5 PF00173.28 KXS21349.1 - 7.8e-25 86.8 0.1 1e-24 86.5 0.1 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain CTNNBL PF08216.11 KXS21350.1 - 3.2e-34 117.2 0.1 8.2e-34 115.9 0.1 1.7 1 0 0 1 1 1 1 Catenin-beta-like, Arm-motif containing nuclear NanE PF04131.14 KXS21350.1 - 0.056 12.6 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase Ribosomal_L31e PF01198.19 KXS21351.1 - 8.3e-39 131.7 0.6 1.1e-38 131.3 0.6 1.2 1 0 0 1 1 1 1 Ribosomal protein L31e TrbC_Ftype PF09673.10 KXS21351.1 - 0.059 13.4 0.1 0.07 13.2 0.1 1.3 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin assembly protein ANAPC8 PF04049.13 KXS21352.1 - 4.9e-34 117.4 0.2 1.5e-33 115.8 0.0 2.0 2 0 0 2 2 2 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_1 PF00515.28 KXS21352.1 - 7e-20 69.9 21.6 0.00029 20.5 0.0 7.9 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_14 PF13428.6 KXS21352.1 - 1.1e-18 66.3 10.9 0.0079 16.9 0.2 8.2 6 2 1 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.6 KXS21352.1 - 1.5e-18 65.4 18.0 0.00029 20.8 0.0 8.3 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_2 PF07719.17 KXS21352.1 - 3.8e-17 60.9 27.2 0.0019 18.1 0.3 9.2 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_19 PF14559.6 KXS21352.1 - 4.1e-12 46.4 6.2 0.02 15.4 0.3 6.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 KXS21352.1 - 3.2e-11 42.7 5.5 8.3e-05 22.2 0.1 5.2 3 2 2 5 5 5 3 TPR repeat TPR_7 PF13176.6 KXS21352.1 - 1.6e-07 30.8 17.7 0.0053 16.7 0.1 7.7 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_17 PF13431.6 KXS21352.1 - 1.7e-07 31.1 12.9 0.0088 16.4 0.1 7.2 7 0 0 7 7 7 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KXS21352.1 - 1.1e-06 28.8 24.3 0.0031 17.7 0.0 6.2 4 2 1 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 KXS21352.1 - 1.3e-06 28.0 14.5 0.21 11.5 0.7 6.8 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_12 PF13424.6 KXS21352.1 - 4e-06 27.0 21.8 0.023 15.0 2.0 7.2 6 2 1 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.6 KXS21352.1 - 2.5e-05 24.8 23.9 0.088 13.5 1.5 7.0 6 2 1 7 7 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 KXS21352.1 - 0.0015 19.0 15.9 64 4.5 0.0 8.0 7 1 1 8 8 8 0 Tetratricopeptide repeat TPR_15 PF13429.6 KXS21352.1 - 0.0048 16.2 4.0 0.0048 16.2 4.0 3.2 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 KXS21352.1 - 0.015 15.4 1.1 1.3 9.3 0.2 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat ChAPs PF09295.10 KXS21352.1 - 0.11 11.5 0.0 7 5.5 0.0 2.4 1 1 1 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) GCV_H PF01597.19 KXS21353.1 - 8.5e-48 161.3 2.4 9.7e-48 161.1 2.4 1.0 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.22 KXS21353.1 - 8.9e-05 22.2 0.6 0.00016 21.4 0.6 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme RnfC_N PF13375.6 KXS21353.1 - 0.00081 19.3 0.3 0.0011 18.9 0.3 1.3 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain DUF2118 PF09891.9 KXS21353.1 - 0.054 13.4 0.0 0.08 12.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) Peptidase_M23 PF01551.22 KXS21353.1 - 0.066 13.4 1.3 2.2 8.5 0.2 2.8 1 1 2 3 3 3 0 Peptidase family M23 Rpr2 PF04032.16 KXS21356.1 - 5.2e-15 55.5 0.0 8.9e-15 54.7 0.0 1.4 1 1 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain SPX PF03105.19 KXS21356.1 - 0.067 13.1 1.1 0.067 13.1 1.1 1.1 1 0 0 1 1 1 0 SPX domain DUF2688 PF10892.8 KXS21356.1 - 1 8.9 4.7 8.6 5.9 1.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2688) SOG2 PF10428.9 KXS21356.1 - 1.7 7.7 9.3 1.9 7.6 9.3 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Ndc1_Nup PF09531.10 KXS21356.1 - 3.7 6.1 5.2 4.2 6.0 5.2 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup 60KD_IMP PF02096.20 KXS21357.1 - 7.3e-34 117.1 4.1 1e-33 116.6 4.1 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein DUF1604 PF07713.13 KXS21358.1 - 6.3e-38 128.5 1.4 6.3e-38 128.5 1.4 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1604) G-patch PF01585.23 KXS21358.1 - 3.6e-06 26.8 2.8 7.8e-06 25.7 0.0 3.1 3 0 0 3 3 3 1 G-patch domain G-patch_2 PF12656.7 KXS21358.1 - 0.00089 19.3 0.2 0.08 13.0 0.0 3.1 2 0 0 2 2 2 1 G-patch domain cwf21 PF08312.12 KXS21359.1 - 5.2e-15 55.3 8.1 7.8e-15 54.8 8.1 1.3 1 0 0 1 1 1 1 cwf21 domain DpnII-MboI PF18742.1 KXS21359.1 - 0.026 14.2 0.0 0.07 12.8 0.0 1.7 2 0 0 2 2 2 0 REase_DpnII-MboI Wtap PF17098.5 KXS21360.1 - 1.3e-36 125.9 15.7 2.3e-36 125.1 15.7 1.5 1 0 0 1 1 1 1 WTAP/Mum2p family Phage_HK97_TLTM PF06120.11 KXS21360.1 - 0.36 10.0 8.9 0.2 10.8 3.6 2.2 1 1 2 3 3 3 0 Tail length tape measure protein DUF641 PF04859.12 KXS21360.1 - 8.3 6.8 17.3 32 4.9 1.1 3.3 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) zf-RING_11 PF17123.5 KXS21361.1 - 6.9e-05 22.5 0.1 0.00016 21.4 0.1 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 KXS21361.1 - 0.054 13.8 0.0 0.14 12.5 0.0 1.7 1 0 0 1 1 1 0 Ring finger domain Adeno_E3_CR2 PF02439.15 KXS21361.1 - 0.077 12.8 0.6 0.077 12.8 0.6 1.8 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 DUF2754 PF10953.8 KXS21361.1 - 0.26 11.6 4.4 0.48 10.7 4.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2754) MFS_1 PF07690.16 KXS21362.1 - 6.8e-44 150.2 54.2 6.8e-44 150.2 54.2 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KXS21362.1 - 9.5e-13 47.4 17.0 1.4e-12 46.8 11.7 2.0 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KXS21362.1 - 6.8e-09 35.1 8.3 6.8e-09 35.1 8.3 3.7 2 2 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 KXS21362.1 - 1.2 7.4 12.7 0.14 10.4 1.2 2.4 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Nnf1 PF03980.14 KXS21363.1 - 9e-14 51.8 6.0 1.5e-13 51.1 6.0 1.4 1 0 0 1 1 1 1 Nnf1 CENP-H PF05837.12 KXS21363.1 - 5.6 7.4 8.0 0.65 10.4 2.3 2.1 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Sacchrp_dh_C PF16653.5 KXS21364.1 - 1.7e-75 254.6 0.0 2.7e-75 253.9 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain AlaDh_PNT_N PF05222.15 KXS21364.1 - 1.6e-27 96.5 0.0 4e-27 95.2 0.0 1.7 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain Sacchrp_dh_NADP PF03435.18 KXS21364.1 - 1.2e-19 70.9 0.0 2.8e-19 69.7 0.0 1.7 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain AlaDh_PNT_C PF01262.21 KXS21364.1 - 2e-08 33.8 0.0 0.0034 16.7 0.0 2.5 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 KXS21364.1 - 6.1e-05 23.1 0.0 0.00018 21.6 0.0 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Semialdhyde_dh PF01118.24 KXS21364.1 - 0.0013 19.2 0.0 0.0055 17.1 0.0 2.1 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 KXS21364.1 - 0.0053 16.7 0.0 0.019 14.8 0.0 2.0 3 0 0 3 3 3 1 NAD(P)H-binding GFO_IDH_MocA PF01408.22 KXS21364.1 - 0.03 15.1 0.0 0.06 14.2 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_7 PF13241.6 KXS21364.1 - 0.066 13.7 0.0 0.16 12.4 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Pkinase PF00069.25 KXS21365.1 - 4.7e-57 193.4 0.1 5.7e-48 163.6 0.0 2.8 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXS21365.1 - 5.2e-25 88.2 0.2 8.7e-15 54.7 0.0 3.1 3 0 0 3 3 3 3 Protein tyrosine kinase APH PF01636.23 KXS21365.1 - 0.00015 21.8 0.8 0.021 14.7 0.3 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KXS21365.1 - 0.00063 18.8 1.0 0.00091 18.3 0.0 1.6 2 0 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 KXS21365.1 - 0.0037 16.6 0.1 0.026 13.9 0.0 2.2 3 0 0 3 3 3 1 Kinase-like Kdo PF06293.14 KXS21365.1 - 0.012 15.0 0.5 0.097 12.0 0.0 2.1 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KXS21365.1 - 0.013 14.3 0.0 0.021 13.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Pkinase_C PF00433.24 KXS21365.1 - 0.19 12.5 0.1 0.19 12.5 0.1 2.3 2 1 0 2 2 2 0 Protein kinase C terminal domain Seadorna_VP7 PF07387.11 KXS21365.1 - 0.24 10.4 0.1 0.37 9.8 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 GCP_C_terminal PF04130.13 KXS21367.1 - 8.8e-36 123.9 0.0 5e-33 114.9 0.0 2.2 2 0 0 2 2 2 2 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 KXS21367.1 - 1.1e-17 64.7 0.0 4e-17 62.8 0.0 1.8 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal ABC_tran PF00005.27 KXS21368.1 - 3.5e-26 92.3 0.0 5.2e-26 91.8 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 KXS21368.1 - 5.9e-17 61.8 2.3 8.5e-17 61.3 2.3 1.2 1 0 0 1 1 1 1 ABC-2 type transporter AAA_21 PF13304.6 KXS21368.1 - 4.6e-06 26.7 6.0 0.0049 16.7 0.1 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KXS21368.1 - 0.00057 20.4 0.0 0.00085 19.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KXS21368.1 - 0.042 14.2 0.6 0.095 13.1 0.6 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 KXS21368.1 - 0.091 12.5 0.2 0.18 11.6 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KXS21368.1 - 0.1 12.5 0.1 0.2 11.6 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_18 PF13238.6 KXS21368.1 - 0.17 12.4 0.1 0.45 11.1 0.1 1.7 2 0 0 2 2 2 0 AAA domain Shigella_OspC PF06128.11 KXS21368.1 - 0.23 11.1 0.0 0.39 10.4 0.0 1.3 1 0 0 1 1 1 0 Shigella flexneri OspC protein ATG13 PF10033.9 KXS21369.1 - 1.2e-22 80.8 0.0 1.5e-22 80.5 0.0 1.0 1 0 0 1 1 1 1 Autophagy-related protein 13 SGS PF05002.15 KXS21370.1 - 4.8e-32 109.9 3.2 6.1e-32 109.6 2.2 1.7 2 0 0 2 2 2 1 SGS domain CS PF04969.16 KXS21370.1 - 5.9e-16 59.3 0.2 9.3e-16 58.6 0.2 1.3 1 0 0 1 1 1 1 CS domain Mito_carr PF00153.27 KXS21371.1 - 1.9e-13 50.1 10.1 0.00071 19.4 0.1 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein Pro_isomerase PF00160.21 KXS21372.1 - 1.5e-52 178.1 0.0 1.7e-52 177.9 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TP2 PF01254.18 KXS21373.1 - 0.052 14.2 3.8 0.052 14.2 3.8 2.0 2 0 0 2 2 2 0 Nuclear transition protein 2 DUF641 PF04859.12 KXS21374.1 - 0.035 14.4 1.3 0.14 12.5 0.2 2.5 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) OEP PF02321.18 KXS21374.1 - 0.082 12.7 8.1 0.081 12.7 6.7 1.6 2 0 0 2 2 2 0 Outer membrane efflux protein DUF2072 PF09845.9 KXS21374.1 - 0.73 10.1 3.1 2.9 8.2 0.0 2.4 2 0 0 2 2 2 0 Zn-ribbon containing protein ABC_tran_CTD PF16326.5 KXS21374.1 - 0.96 9.7 10.0 5.6 7.3 5.2 2.9 3 0 0 3 3 3 0 ABC transporter C-terminal domain Spc24 PF08286.11 KXS21374.1 - 1.7 8.9 6.5 1.5 9.1 0.0 2.9 2 2 0 2 2 2 0 Spc24 subunit of Ndc80 KASH_CCD PF14662.6 KXS21374.1 - 8.4 6.2 10.8 2 8.2 6.9 2.0 3 0 0 3 3 3 0 Coiled-coil region of CCDC155 or KASH ubiquitin PF00240.23 KXS21375.1 - 6.3e-39 131.6 0.6 1.7e-23 82.2 0.3 2.2 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.8 KXS21375.1 - 3.9e-16 58.6 0.8 5.7e-10 38.9 0.4 2.2 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 KXS21375.1 - 2e-05 24.4 0.0 0.0041 17.0 0.0 2.1 2 0 0 2 2 2 2 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_2 PF14560.6 KXS21375.1 - 2.7e-05 24.5 0.2 0.04 14.4 0.1 2.7 2 1 0 2 2 2 2 Ubiquitin-like domain Ubiquitin_5 PF18037.1 KXS21375.1 - 0.00033 21.0 0.3 0.0062 16.9 0.1 2.2 1 1 1 2 2 2 1 Ubiquitin-like domain DUF2407 PF10302.9 KXS21375.1 - 0.024 15.2 0.1 2 9.0 0.0 2.2 2 0 0 2 2 2 0 DUF2407 ubiquitin-like domain Peptidase_S9_N PF02897.15 KXS21376.1 - 2.7e-88 296.5 4.2 3.4e-88 296.2 4.2 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 KXS21376.1 - 2.3e-56 190.7 0.1 5.1e-55 186.2 0.0 2.3 2 0 0 2 2 2 1 Prolyl oligopeptidase family ThiF PF00899.21 KXS21377.1 - 4.9e-36 124.3 0.0 6.5e-36 123.9 0.0 1.1 1 0 0 1 1 1 1 ThiF family E1_4HB PF16191.5 KXS21377.1 - 0.004 17.3 0.0 0.0083 16.3 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle Borrelia_P83 PF05262.11 KXS21378.1 - 0.28 9.6 8.1 0.34 9.4 8.1 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein Presenilin PF01080.17 KXS21378.1 - 0.48 9.1 3.5 0.54 9.0 3.5 1.1 1 0 0 1 1 1 0 Presenilin Activator_LAG-3 PF11498.8 KXS21378.1 - 0.87 8.5 10.1 1.1 8.1 10.1 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 FHA PF00498.26 KXS21379.1 - 0.00064 20.0 0.0 0.0013 19.1 0.0 1.5 1 0 0 1 1 1 1 FHA domain Choline_transpo PF04515.12 KXS21380.1 - 1.7e-44 152.4 8.2 1.8e-44 152.3 8.2 1.0 1 0 0 1 1 1 1 Plasma-membrane choline transporter PIH1_CS PF18201.1 KXS21381.1 - 8.1e-13 48.6 0.1 1.2e-12 48.1 0.1 1.3 1 0 0 1 1 1 1 PIH1 CS-like domain ArsA_HSP20 PF17886.1 KXS21381.1 - 0.023 14.2 0.0 0.038 13.5 0.0 1.3 1 0 0 1 1 1 0 HSP20-like domain found in ArsA XPA_C PF05181.12 KXS21382.1 - 3e-24 84.7 3.0 1.4e-23 82.6 1.8 2.3 2 0 0 2 2 2 1 XPA protein C-terminus XPA_N PF01286.18 KXS21382.1 - 0.00016 21.7 5.1 0.00016 21.7 5.1 1.8 2 0 0 2 2 2 1 XPA protein N-terminal ThiC_Rad_SAM PF01964.18 KXS21382.1 - 0.3 9.8 1.2 0.48 9.1 1.2 1.2 1 0 0 1 1 1 0 Radical SAM ThiC family Ribosomal_L14e PF01929.17 KXS21383.1 - 5.1e-27 94.2 4.4 5.1e-27 94.2 4.4 1.6 2 0 0 2 2 2 1 Ribosomal protein L14 KOW PF00467.29 KXS21383.1 - 0.0012 18.7 0.1 0.0022 17.9 0.1 1.5 1 0 0 1 1 1 1 KOW motif Stc1 PF12898.7 KXS21384.1 - 0.0031 18.0 10.9 0.0067 16.9 10.9 1.5 1 1 0 1 1 1 1 Stc1 domain Peptidase_M8 PF01457.16 KXS21384.1 - 0.026 13.2 0.8 0.029 13.1 0.8 1.0 1 0 0 1 1 1 0 Leishmanolysin DUF4193 PF13834.6 KXS21384.1 - 5.8 7.5 8.7 8 7.0 2.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4193) Oxysterol_BP PF01237.18 KXS21385.1 - 3.9e-108 361.6 0.0 9.2e-108 360.4 0.0 1.7 1 0 0 1 1 1 1 Oxysterol-binding protein PH PF00169.29 KXS21385.1 - 6.5e-06 26.6 0.0 1.8e-05 25.2 0.0 1.8 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 KXS21385.1 - 1.6e-05 25.1 0.0 4.1e-05 23.8 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain Ank_5 PF13857.6 KXS21385.1 - 0.00037 20.7 0.0 0.0096 16.2 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXS21385.1 - 0.001 19.3 0.0 5.2 8.0 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 KXS21385.1 - 0.074 13.6 0.0 6.6 7.4 0.0 2.3 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) Ank PF00023.30 KXS21385.1 - 0.15 12.6 1.0 11 6.7 0.0 3.4 5 0 0 5 5 5 0 Ankyrin repeat PRP38_assoc PF12871.7 KXS21386.1 - 0.0013 19.3 29.5 0.0013 19.3 29.5 7.6 7 1 2 9 9 9 1 Pre-mRNA-splicing factor 38-associated hydrophilic C-term SprA-related PF12118.8 KXS21386.1 - 0.004 16.4 8.8 0.0068 15.6 8.8 1.3 1 0 0 1 1 1 1 SprA-related family Ribosomal_S8e PF01201.22 KXS21388.1 - 8.3e-56 188.0 0.3 9.9e-56 187.7 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e TAF1_subA PF14929.6 KXS21389.1 - 1.3e-08 34.7 0.0 0.00022 20.8 0.0 2.2 2 0 0 2 2 2 2 TAF RNA Polymerase I subunit A TPR_14 PF13428.6 KXS21389.1 - 7.4e-06 26.4 6.3 0.063 14.1 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 KXS21389.1 - 0.039 14.5 0.1 19 5.9 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.14 KXS21389.1 - 0.13 13.0 4.5 15 6.6 0.9 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 KXS21389.1 - 0.2 11.9 0.4 3.2 8.1 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3237 PF11578.8 KXS21390.1 - 1.2e-44 151.8 0.0 1.3e-44 151.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) Epimerase PF01370.21 KXS21391.1 - 8.6e-06 25.4 0.0 1.1e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KXS21391.1 - 0.0021 18.0 0.0 0.0039 17.1 0.0 1.4 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 KXS21391.1 - 0.01 15.3 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KXS21391.1 - 0.021 14.7 0.0 0.082 12.8 0.0 2.0 1 1 0 1 1 1 0 NAD(P)H-binding Stc1 PF12898.7 KXS21392.1 - 9.5e-06 26.1 12.3 5.5e-05 23.6 11.5 2.0 1 1 1 2 2 2 1 Stc1 domain zinc_ribbon_6 PF14599.6 KXS21392.1 - 0.38 10.8 7.7 0.78 9.8 1.2 2.7 1 1 1 2 2 2 0 Zinc-ribbon CENP-F_leu_zip PF10473.9 KXS21393.1 - 3.3e-06 27.2 82.5 3.1e-05 24.0 8.7 8.5 2 2 5 8 8 8 5 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fez1 PF06818.15 KXS21393.1 - 0.0016 18.9 75.4 0.0072 16.8 16.3 5.6 1 1 3 5 5 5 2 Fez1 PI3K_P85_iSH2 PF16454.5 KXS21393.1 - 0.0098 15.5 14.2 0.0098 15.5 14.2 6.3 3 2 2 6 6 6 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain ATG16 PF08614.11 KXS21393.1 - 0.098 12.9 90.4 0.36 11.0 23.0 6.5 2 1 5 7 7 7 0 Autophagy protein 16 (ATG16) DnaB_bind PF10410.9 KXS21393.1 - 0.26 11.5 9.6 0.34 11.1 0.3 4.1 4 0 0 4 4 4 0 DnaB-helicase binding domain of primase DUF1949 PF09186.11 KXS21393.1 - 1.3 8.9 5.4 2.4 8.1 0.0 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF1949) GAS PF13851.6 KXS21393.1 - 1.9 7.8 80.4 0.0088 15.4 21.2 6.6 2 1 5 7 7 7 0 Growth-arrest specific micro-tubule binding ADIP PF11559.8 KXS21393.1 - 4.1 7.5 86.3 2.8 8.0 10.0 7.2 2 1 5 7 7 7 0 Afadin- and alpha -actinin-Binding APG6_N PF17675.1 KXS21393.1 - 5.3 7.6 91.4 0.85 10.2 9.1 6.8 2 1 5 7 7 7 0 Apg6 coiled-coil region NPV_P10 PF05531.12 KXS21394.1 - 2.1e-06 28.1 13.1 0.13 12.8 0.1 6.0 5 0 0 5 5 5 1 Nucleopolyhedrovirus P10 protein PspA_IM30 PF04012.12 KXS21394.1 - 0.0039 16.8 10.0 0.0039 16.8 10.0 5.9 4 2 2 6 6 4 1 PspA/IM30 family DUF2968 PF11180.8 KXS21394.1 - 0.0049 16.5 15.7 0.0049 16.5 15.7 6.2 5 2 0 6 6 6 2 Protein of unknown function (DUF2968) HrpB7 PF09486.10 KXS21394.1 - 0.01 16.2 0.6 0.01 16.2 0.6 6.7 4 3 0 5 5 3 0 Bacterial type III secretion protein (HrpB7) Filament PF00038.21 KXS21394.1 - 0.032 13.8 75.6 0.035 13.7 4.9 5.7 4 1 0 4 4 4 0 Intermediate filament protein XhlA PF10779.9 KXS21394.1 - 0.14 12.4 41.6 1 9.6 0.1 8.5 7 1 0 7 7 7 0 Haemolysin XhlA AKNA PF12443.8 KXS21394.1 - 0.58 10.8 14.4 2.7 8.7 1.6 4.4 3 1 0 3 3 3 0 AT-hook-containing transcription factor Spc7 PF08317.11 KXS21394.1 - 1.3 7.8 68.8 0.052 12.4 3.7 6.2 4 1 2 6 6 6 0 Spc7 kinetochore protein Baculo_PEP_C PF04513.12 KXS21394.1 - 2.2 8.3 18.5 1.7 8.7 1.3 5.2 3 1 2 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4988 PF16378.5 KXS21394.1 - 2.8 7.6 4.7 44 3.7 0.1 3.6 2 1 1 3 3 3 0 Domain of unknown function IL11 PF07400.11 KXS21394.1 - 2.9 7.5 11.4 8.4 6.0 0.2 4.3 3 1 1 4 4 4 0 Interleukin 11 DUF3138 PF11336.8 KXS21394.1 - 3.2 6.3 7.7 8.9 4.8 2.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) Golgin_A5 PF09787.9 KXS21394.1 - 3.3 7.1 76.4 0.11 12.0 19.0 5.5 3 1 3 6 6 6 0 Golgin subfamily A member 5 DUF1664 PF07889.12 KXS21394.1 - 3.5 7.7 37.4 0.22 11.6 0.2 6.9 7 1 1 8 8 8 0 Protein of unknown function (DUF1664) Phage_GP20 PF06810.11 KXS21394.1 - 3.9 7.3 47.6 0.76 9.6 1.1 6.4 4 1 2 6 6 6 0 Phage minor structural protein GP20 FlaC_arch PF05377.11 KXS21394.1 - 8.3 6.9 33.8 1.9 8.9 1.6 7.3 6 2 1 7 7 7 0 Flagella accessory protein C (FlaC) DUF2009 PF09418.10 KXS21395.1 - 2.1e-210 699.6 0.0 2.4e-210 699.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) zf-B_box PF00643.24 KXS21396.1 - 2.9e-07 30.5 7.7 4.1e-07 30.0 7.7 1.2 1 0 0 1 1 1 1 B-box zinc finger CEBP_ZZ PF16366.5 KXS21396.1 - 0.012 15.8 5.6 0.021 15.1 5.6 1.3 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain VOMI PF03762.17 KXS21397.1 - 0.0064 16.6 0.1 0.01 16.0 0.1 1.2 1 0 0 1 1 1 1 Vitelline membrane outer layer protein I (VOMI) NOA36 PF06524.12 KXS21397.1 - 0.0075 15.6 5.4 0.012 14.9 5.4 1.4 1 0 0 1 1 1 1 NOA36 protein Nop14 PF04147.12 KXS21397.1 - 0.01 14.1 6.1 0.011 14.0 6.1 1.2 1 0 0 1 1 1 0 Nop14-like family PTPRCAP PF15713.5 KXS21397.1 - 0.034 14.4 10.7 0.058 13.7 10.7 1.3 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated CDC45 PF02724.14 KXS21397.1 - 0.079 11.2 7.6 0.088 11.1 7.6 1.1 1 0 0 1 1 1 0 CDC45-like protein API5 PF05918.11 KXS21397.1 - 0.13 11.0 3.3 0.17 10.7 3.3 1.0 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Cnd2 PF05786.14 KXS21397.1 - 0.2 10.3 11.3 0.29 9.8 11.3 1.2 1 0 0 1 1 1 0 Condensin complex subunit 2 PPP4R2 PF09184.11 KXS21397.1 - 0.33 10.5 8.4 0.47 10.0 8.4 1.2 1 0 0 1 1 1 0 PPP4R2 Myc_N PF01056.18 KXS21397.1 - 0.36 10.7 5.4 0.6 10.0 5.4 1.3 1 0 0 1 1 1 0 Myc amino-terminal region DNA_pol_phi PF04931.13 KXS21397.1 - 0.57 8.2 11.5 0.75 7.8 11.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi TLP-20 PF06088.11 KXS21397.1 - 0.62 9.9 3.2 0.93 9.4 3.2 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Paf1 PF03985.13 KXS21397.1 - 0.66 8.9 10.1 0.79 8.7 10.1 1.1 1 0 0 1 1 1 0 Paf1 FAM176 PF14851.6 KXS21397.1 - 0.93 9.2 6.7 2.2 7.9 6.7 1.6 1 0 0 1 1 1 0 FAM176 family PBP1_TM PF14812.6 KXS21397.1 - 1 9.8 13.2 2.4 8.6 13.2 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF913 PF06025.12 KXS21397.1 - 2.6 6.9 5.3 3.7 6.4 5.3 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF4746 PF15928.5 KXS21397.1 - 3.9 6.8 8.2 6.1 6.2 8.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) RR_TM4-6 PF06459.12 KXS21397.1 - 6.7 6.5 10.0 8.7 6.1 10.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Radial_spoke PF04712.12 KXS21397.1 - 7.6 5.4 13.1 12 4.7 13.1 1.2 1 0 0 1 1 1 0 Radial spokehead-like protein Merozoite_SPAM PF07133.11 KXS21397.1 - 9.7 6.1 20.7 16 5.4 20.7 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Sec7 PF01369.20 KXS21398.1 - 4.4e-64 215.5 0.0 3.8e-58 196.2 0.0 2.2 2 0 0 2 2 2 2 Sec7 domain PH PF00169.29 KXS21398.1 - 5.3e-17 62.2 0.1 9.1e-13 48.6 0.0 2.4 2 0 0 2 2 2 2 PH domain PH_11 PF15413.6 KXS21398.1 - 0.00066 20.1 0.0 0.084 13.3 0.0 2.6 2 0 0 2 2 2 1 Pleckstrin homology domain PRIMA1 PF16101.5 KXS21399.1 - 0.81 9.7 9.1 1.2 9.1 9.1 1.2 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Acetyltransf_9 PF13527.7 KXS21400.1 - 5.4e-07 29.7 0.0 1.2e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXS21400.1 - 7.8e-05 23.0 0.0 0.0009 19.6 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KXS21400.1 - 0.0017 18.3 0.0 0.0061 16.5 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXS21400.1 - 0.0025 18.0 0.0 0.0065 16.7 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_CG PF14542.6 KXS21400.1 - 0.038 14.1 0.0 0.094 12.9 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase p450 PF00067.22 KXS21401.1 - 2.9e-76 257.1 0.0 3.9e-76 256.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1192 PF06698.11 KXS21402.1 - 0.27 11.3 1.8 1.1 9.3 1.7 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1192) SET PF00856.28 KXS21403.1 - 6.8e-07 29.8 0.0 1.1e-06 29.1 0.0 1.3 1 0 0 1 1 1 1 SET domain MFS_1 PF07690.16 KXS21404.1 - 1.9e-48 165.2 44.4 1.9e-48 165.2 44.4 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KXS21404.1 - 3.4e-20 72.0 25.9 4.9e-20 71.5 25.9 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KXS21404.1 - 2.5e-11 43.1 13.3 2.5e-11 43.1 13.3 3.2 2 1 1 3 3 3 2 Sugar (and other) transporter OATP PF03137.20 KXS21404.1 - 0.012 14.0 14.4 0.0066 14.8 2.2 2.6 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Pox_A14 PF05767.12 KXS21404.1 - 5.1 7.3 9.8 0.19 11.9 1.0 3.2 2 1 1 3 3 3 0 Poxvirus virion envelope protein A14 ANAPC5 PF12862.7 KXS21405.1 - 0.017 15.2 0.0 0.044 13.8 0.0 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 5 TPR_6 PF13174.6 KXS21405.1 - 0.036 14.7 0.2 0.83 10.4 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 KXS21405.1 - 0.04 14.6 1.5 0.04 14.6 1.5 5.8 4 2 2 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 KXS21405.1 - 0.12 12.5 3.4 0.16 12.1 0.0 3.0 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KXS21405.1 - 0.88 10.6 19.2 0.81 10.7 0.2 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 KXS21405.1 - 1.9 8.8 0.0 1.9 8.8 0.0 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 KXS21405.1 - 4.6 7.2 8.0 1.6 8.7 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat SIR2 PF02146.17 KXS21408.1 - 4.3e-09 36.6 0.0 8.1e-06 25.9 0.0 2.2 2 0 0 2 2 2 2 Sir2 family BPL_LplA_LipB PF03099.19 KXS21409.1 - 1.5e-05 24.9 0.0 2.5e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family UCH PF00443.29 KXS21410.1 - 0.001 18.6 0.0 0.0057 16.2 0.0 1.9 2 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase GCFC PF07842.12 KXS21412.1 - 1.6e-41 142.8 8.3 3.7e-41 141.6 8.3 1.5 1 1 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.23 KXS21412.1 - 2.2e-15 56.3 2.4 2.2e-15 56.3 2.4 2.1 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 KXS21412.1 - 7e-10 38.8 0.7 7e-10 38.8 0.7 2.7 3 0 0 3 3 3 1 G-patch domain TIP_N PF12457.8 KXS21412.1 - 4.8e-06 26.9 11.9 4.8e-06 26.9 11.9 2.9 2 1 0 2 2 2 1 Tuftelin interacting protein N terminal PIEZO PF15917.5 KXS21412.1 - 0.24 10.9 0.5 0.43 10.0 0.5 1.3 1 0 0 1 1 1 0 Piezo Abhydrolase_3 PF07859.13 KXS21413.1 - 4.3e-44 150.9 2.9 8.8e-34 117.2 0.1 3.2 3 1 0 3 3 3 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KXS21413.1 - 4.9e-13 48.7 0.0 5.2e-12 45.3 0.0 2.2 2 1 0 2 2 2 1 Steryl acetyl hydrolase COesterase PF00135.28 KXS21413.1 - 0.12 11.2 0.0 1.4 7.7 0.0 2.0 2 0 0 2 2 2 0 Carboxylesterase family Mg_trans_NIPA PF05653.14 KXS21414.1 - 2.4e-81 273.1 19.9 2.9e-81 272.8 19.9 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 KXS21414.1 - 4e-05 23.8 3.8 4e-05 23.8 3.8 3.9 3 1 0 3 3 3 2 EamA-like transporter family ASFV_J13L PF05568.11 KXS21414.1 - 2.3 7.9 10.5 0.045 13.5 3.1 1.9 2 0 0 2 2 2 0 African swine fever virus J13L protein ACT_6 PF13740.6 KXS21415.1 - 1.1e-16 60.5 0.0 1.3e-08 34.6 0.0 2.3 2 0 0 2 2 2 2 ACT domain ACT PF01842.25 KXS21415.1 - 2e-11 43.4 0.1 4.6e-07 29.5 0.0 2.5 2 0 0 2 2 2 2 ACT domain ACT_4 PF13291.6 KXS21415.1 - 2.8e-07 31.0 0.0 0.00024 21.6 0.0 2.3 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.6 KXS21415.1 - 0.00057 19.6 0.0 0.0015 18.2 0.0 1.7 2 0 0 2 2 2 1 ACT domain PMI_typeI PF01238.21 KXS21416.1 - 4.8e-105 351.8 0.0 7.1e-105 351.2 0.0 1.2 1 0 0 1 1 1 1 Phosphomannose isomerase type I Usp PF00582.26 KXS21417.1 - 1e-18 68.2 1.8 5.4e-18 65.9 1.8 1.9 1 1 0 1 1 1 1 Universal stress protein family MutS_V PF00488.21 KXS21418.1 - 1.3e-37 129.6 0.2 2.5e-37 128.7 0.2 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KXS21418.1 - 6.9e-21 75.3 0.6 9.5e-21 74.9 0.1 1.5 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.18 KXS21418.1 - 5.1e-06 26.8 0.0 9.4e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 MutS family domain IV MutS_V PF00488.21 KXS21419.1 - 0.027 14.5 0.0 0.038 14.0 0.0 1.3 1 0 0 1 1 1 0 MutS domain V RINGv PF12906.7 KXS21420.1 - 3.2e-16 59.2 9.3 5.7e-16 58.4 9.3 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 KXS21420.1 - 0.13 12.6 7.5 0.23 11.8 7.5 1.4 1 0 0 1 1 1 0 Ring finger domain GCS2 PF04107.13 KXS21421.1 - 0.08 12.3 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Glutamate-cysteine ligase family 2(GCS2) CUE PF02845.16 KXS21421.1 - 0.16 11.7 0.0 0.34 10.7 0.0 1.5 1 0 0 1 1 1 0 CUE domain IBR PF01485.21 KXS21422.1 - 3e-05 24.2 5.4 3e-05 24.2 5.4 3.8 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain AMPK1_CBM PF16561.5 KXS21423.1 - 4.6e-13 49.2 0.0 9.5e-13 48.2 0.0 1.5 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase Ank_3 PF13606.6 KXS21423.1 - 0.0021 18.4 0.0 4.4 8.2 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 KXS21423.1 - 0.0029 17.9 0.0 0.022 15.0 0.0 2.4 1 1 0 1 1 1 1 Ankyrin repeats (many copies) CBM_20 PF00686.19 KXS21423.1 - 0.011 15.6 0.0 0.052 13.5 0.0 2.1 2 0 0 2 2 2 0 Starch binding domain Ank_2 PF12796.7 KXS21423.1 - 0.065 13.8 0.0 0.16 12.6 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Prominin PF05478.11 KXS21423.1 - 0.076 11.0 0.6 0.11 10.4 0.6 1.1 1 0 0 1 1 1 0 Prominin Cep57_CLD_2 PF14197.6 KXS21423.1 - 1.3 9.2 3.7 22 5.2 0.1 2.9 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 Fez1 PF06818.15 KXS21423.1 - 8.3 6.8 10.3 2.6 8.4 7.1 1.8 2 0 0 2 2 2 0 Fez1 CENP-Q PF13094.6 KXS21423.1 - 9.4 6.4 8.3 2.3 8.4 4.5 1.9 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Amidohydro_2 PF04909.14 KXS21424.1 - 1.4e-18 67.7 0.2 2.8e-18 66.7 0.2 1.4 1 0 0 1 1 1 1 Amidohydrolase UxaC PF02614.14 KXS21424.1 - 0.18 10.6 0.3 4.7 6.0 0.0 2.1 2 0 0 2 2 2 0 Glucuronate isomerase UBA PF00627.31 KXS21425.1 - 3.8e-08 33.1 0.1 0.00015 21.6 0.1 2.3 2 0 0 2 2 2 2 UBA/TS-N domain HOIP-UBA PF16678.5 KXS21425.1 - 0.00023 21.2 0.0 0.0021 18.0 0.0 2.0 2 0 0 2 2 2 1 HOIP UBA domain pair ApoO PF09769.9 KXS21426.1 - 3.4e-17 62.6 1.3 5.1e-16 58.8 0.1 2.2 1 1 1 2 2 2 1 Apolipoprotein O 7TM_GPCR_Srz PF10325.9 KXS21426.1 - 0.054 12.8 0.0 0.079 12.3 0.0 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srz COG6 PF06419.11 KXS21426.1 - 0.071 11.3 0.1 0.28 9.4 0.1 1.7 2 0 0 2 2 2 0 Conserved oligomeric complex COG6 Spore_III_AE PF09546.10 KXS21426.1 - 0.12 11.6 1.3 0.18 11.0 0.2 1.6 2 0 0 2 2 2 0 Stage III sporulation protein AE (spore_III_AE) Trans_reg_C PF00486.28 KXS21426.1 - 0.16 12.1 0.2 20 5.4 0.0 2.5 2 0 0 2 2 2 0 Transcriptional regulatory protein, C terminal CoA_transf_3 PF02515.17 KXS21427.1 - 4.4e-51 174.1 1.6 1.2e-43 149.7 0.0 2.4 2 1 0 2 2 2 2 CoA-transferase family III CBM_1 PF00734.18 KXS21428.1 - 4.4e-13 48.9 10.9 1.5e-12 47.2 10.9 2.0 1 0 0 1 1 1 1 Fungal cellulose binding domain HAD PF12710.7 KXS21429.1 - 2e-11 44.6 0.1 3.4e-11 43.9 0.1 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 KXS21429.1 - 1.5e-05 24.5 0.0 2.2e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Putative Phosphatase Hydrolase PF00702.26 KXS21429.1 - 0.0012 19.2 1.3 0.43 10.8 1.3 3.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Pkinase PF00069.25 KXS21431.1 - 2e-35 122.5 0.0 2.3e-34 119.0 0.0 2.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS21431.1 - 9.7e-20 70.9 0.0 2.9e-18 66.1 0.0 2.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXS21431.1 - 0.0021 17.4 0.0 0.0033 16.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KXS21431.1 - 0.0084 16.0 0.2 0.041 13.8 0.1 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family MMADHC PF10229.9 KXS21432.1 - 8.3e-14 52.0 0.0 1.7e-13 51.0 0.0 1.5 1 1 0 1 1 1 1 Methylmalonic aciduria and homocystinuria type D protein Peptidase_M14 PF00246.24 KXS21433.1 - 7.4e-70 236.0 0.0 9.8e-70 235.6 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.16 KXS21433.1 - 0.11 12.9 0.0 0.21 12.0 0.0 1.4 1 0 0 1 1 1 0 Carboxypeptidase activation peptide Hist_deacetyl PF00850.19 KXS21434.1 - 1.3e-59 202.1 0.0 1.8e-59 201.7 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain LINES_C PF14695.6 KXS21434.1 - 0.1 12.0 0.1 0.18 11.2 0.1 1.4 1 0 0 1 1 1 0 Lines C-terminus Sas10 PF09368.10 KXS21435.1 - 9.7e-23 80.4 4.2 9.7e-23 80.4 4.2 3.7 3 0 0 3 3 3 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 KXS21435.1 - 4.4e-06 27.2 0.0 1.4e-05 25.6 0.0 1.9 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Totivirus_coat PF05518.11 KXS21435.1 - 6.6 4.6 9.1 9.2 4.2 9.1 1.1 1 0 0 1 1 1 0 Totivirus coat protein EPSP_synthase PF00275.20 KXS21436.1 - 6.4e-114 380.9 1.6 7.4e-86 288.4 0.0 2.2 2 0 0 2 2 2 2 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.20 KXS21436.1 - 2e-94 315.6 0.0 4.5e-94 314.5 0.0 1.6 1 0 0 1 1 1 1 3-dehydroquinate synthase DHquinase_I PF01487.15 KXS21436.1 - 7.1e-50 170.4 0.0 2e-29 103.5 0.0 2.5 2 0 0 2 2 2 2 Type I 3-dehydroquinase SKI PF01202.22 KXS21436.1 - 3.3e-34 118.3 0.5 9e-34 116.9 0.0 2.0 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.11 KXS21436.1 - 1.2e-21 76.7 0.0 4.5e-21 74.9 0.0 2.0 2 0 0 2 2 2 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 KXS21436.1 - 7.8e-09 35.2 0.0 3.8e-08 32.9 0.0 2.2 2 0 0 2 2 2 1 Shikimate 5'-dehydrogenase C-terminal domain Fe-ADH_2 PF13685.6 KXS21436.1 - 2.6e-07 30.6 0.2 1.9e-06 27.8 0.0 2.4 3 0 0 3 3 3 1 Iron-containing alcohol dehydrogenase Shikimate_DH PF01488.20 KXS21436.1 - 5.5e-06 26.5 0.2 2.5e-05 24.4 0.0 2.0 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Fe-ADH PF00465.19 KXS21436.1 - 0.00085 18.2 1.5 0.0041 16.0 1.5 2.1 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Tautomerase_3 PF14832.6 KXS21438.1 - 7.8e-46 155.7 0.1 8.7e-46 155.5 0.1 1.0 1 0 0 1 1 1 1 Putative oxalocrotonate tautomerase enzyme Tautomerase PF01361.21 KXS21438.1 - 0.00014 21.7 0.0 0.0007 19.5 0.0 2.2 1 1 1 2 2 2 1 Tautomerase enzyme WH1 PF00568.23 KXS21438.1 - 0.14 12.1 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 WH1 domain Tautomerase_3 PF14832.6 KXS21439.1 - 6.5e-22 78.2 0.0 7.8e-22 78.0 0.0 1.1 1 0 0 1 1 1 1 Putative oxalocrotonate tautomerase enzyme WD40 PF00400.32 KXS21440.1 - 4.4e-10 40.0 6.4 0.00033 21.4 0.1 6.4 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXS21440.1 - 0.00018 21.7 0.2 0.58 10.5 0.0 4.7 4 1 1 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain PALB2_WD40 PF16756.5 KXS21440.1 - 0.033 13.1 0.0 0.25 10.2 0.0 2.1 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain Nup160 PF11715.8 KXS21440.1 - 0.034 12.8 0.0 0.11 11.2 0.0 1.8 1 1 0 1 1 1 0 Nucleoporin Nup120/160 WD40_like PF17005.5 KXS21440.1 - 0.23 10.8 0.0 17 4.6 0.0 2.7 3 0 0 3 3 3 0 WD40-like domain KASH_CCD PF14662.6 KXS21442.1 - 0.005 16.7 5.1 0.0071 16.2 5.1 1.1 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH FlxA PF14282.6 KXS21442.1 - 0.005 16.8 12.2 0.0077 16.2 12.2 1.2 1 0 0 1 1 1 1 FlxA-like protein Spc7 PF08317.11 KXS21442.1 - 0.0095 14.9 1.4 0.013 14.4 1.4 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF4763 PF15960.5 KXS21442.1 - 0.035 13.4 2.7 0.046 13.0 2.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) DUF1664 PF07889.12 KXS21442.1 - 0.037 14.1 0.6 0.062 13.3 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) BLOC1_2 PF10046.9 KXS21442.1 - 0.037 14.3 1.5 0.055 13.8 1.5 1.2 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spc29 PF17082.5 KXS21442.1 - 0.076 12.8 0.1 0.099 12.5 0.1 1.1 1 0 0 1 1 1 0 Spindle Pole Component 29 Spc24 PF08286.11 KXS21442.1 - 0.12 12.6 0.6 0.17 12.1 0.6 1.2 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 bZIP_2 PF07716.15 KXS21442.1 - 0.19 11.8 4.4 0.15 12.2 2.9 1.5 1 1 0 1 1 1 0 Basic region leucine zipper Surfac_D-trimer PF09006.11 KXS21442.1 - 0.75 9.7 4.5 1.4 8.8 4.5 1.5 1 0 0 1 1 1 0 Lung surfactant protein D coiled-coil trimerisation DivIC PF04977.15 KXS21442.1 - 6.1 6.7 7.1 25 4.7 0.6 2.0 1 1 1 2 2 2 0 Septum formation initiator DSBA PF01323.20 KXS21444.1 - 2.6e-32 112.2 0.0 5.1e-32 111.2 0.0 1.4 2 0 0 2 2 2 1 DSBA-like thioredoxin domain ATG16 PF08614.11 KXS21445.1 - 3.2e-05 24.2 28.7 0.00022 21.5 10.6 7.0 1 1 4 6 6 5 3 Autophagy protein 16 (ATG16) Spc7 PF08317.11 KXS21445.1 - 5.8e-05 22.1 92.6 0.0024 16.8 12.2 7.5 3 2 4 7 7 7 5 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 KXS21445.1 - 0.00015 21.8 102.1 0.023 14.8 6.2 9.7 5 3 4 9 9 9 4 TPR/MLP1/MLP2-like protein PRKG1_interact PF15898.5 KXS21445.1 - 0.0009 20.1 6.4 0.0009 20.1 6.4 8.8 3 2 6 10 10 8 3 cGMP-dependent protein kinase interacting domain GIT_CC PF16559.5 KXS21445.1 - 0.0039 17.0 12.1 3.3 7.6 0.3 5.8 5 0 0 5 5 5 1 GIT coiled-coil Rho guanine nucleotide exchange factor NPV_P10 PF05531.12 KXS21445.1 - 0.0039 17.6 0.5 0.0039 17.6 0.5 7.3 9 0 0 9 9 9 1 Nucleopolyhedrovirus P10 protein Exonuc_VII_L PF02601.15 KXS21445.1 - 0.0059 16.2 0.8 0.0059 16.2 0.8 4.9 1 1 1 2 2 1 1 Exonuclease VII, large subunit Lipoprotein_6 PF01441.19 KXS21445.1 - 0.0059 16.6 0.6 0.0059 16.6 0.6 4.6 5 1 1 6 6 5 1 Lipoprotein DUF4201 PF13870.6 KXS21445.1 - 0.0087 15.8 6.3 0.0087 15.8 6.3 8.9 7 3 0 8 8 8 2 Domain of unknown function (DUF4201) DHR10 PF18595.1 KXS21445.1 - 0.013 15.5 4.5 0.013 15.5 4.5 9.7 7 2 1 9 9 9 0 Designed helical repeat protein 10 domain FlaC_arch PF05377.11 KXS21445.1 - 0.016 15.6 59.0 0.93 9.9 0.1 10.9 11 0 0 11 11 11 0 Flagella accessory protein C (FlaC) DUF2353 PF09789.9 KXS21445.1 - 0.042 13.2 87.4 0.71 9.2 21.5 5.1 1 1 3 5 5 5 0 Uncharacterized coiled-coil protein (DUF2353) MapZ_EC1 PF18041.1 KXS21445.1 - 0.055 13.7 0.2 0.055 13.7 0.2 5.6 6 1 0 7 7 6 0 MapZ extracellular domain 1 DivIC PF04977.15 KXS21445.1 - 0.066 13.0 73.4 0.2 11.5 0.2 11.7 11 1 1 12 12 11 0 Septum formation initiator LPP PF04728.13 KXS21445.1 - 0.12 12.7 48.1 0.6 10.5 0.8 9.8 9 2 1 10 10 10 0 Lipoprotein leucine-zipper ZapB PF06005.12 KXS21445.1 - 0.13 12.8 103.0 0.69 10.4 0.3 11.6 9 2 1 11 11 11 0 Cell division protein ZapB DUF4407 PF14362.6 KXS21445.1 - 0.16 11.3 89.0 0.17 11.2 10.4 5.6 1 1 4 5 5 4 0 Domain of unknown function (DUF4407) DUF2576 PF10845.8 KXS21445.1 - 0.61 9.7 8.0 9.1 6.0 0.0 5.4 5 0 0 5 5 4 0 Protein of unknown function (DUF2576) WEMBL PF05701.11 KXS21445.1 - 1 8.0 82.7 0.29 9.8 25.1 5.0 1 1 4 5 5 5 0 Weak chloroplast movement under blue light Atg14 PF10186.9 KXS21445.1 - 1.7 7.7 79.2 0.017 14.2 8.8 6.2 1 1 2 6 6 6 0 Vacuolar sorting 38 and autophagy-related subunit 14 Fez1 PF06818.15 KXS21445.1 - 1.9 8.9 93.0 11 6.4 9.5 5.8 1 1 6 7 7 7 0 Fez1 DUF3138 PF11336.8 KXS21445.1 - 3.5 6.1 10.7 5.6 5.5 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3138) Golgin_A5 PF09787.9 KXS21445.1 - 3.6 7.0 91.6 0.18 11.3 20.2 5.4 1 1 4 5 5 5 0 Golgin subfamily A member 5 Baculo_PEP_C PF04513.12 KXS21445.1 - 3.8 7.5 16.4 2.2 8.3 1.6 4.9 7 0 0 7 7 7 0 Baculovirus polyhedron envelope protein, PEP, C terminus CorA PF01544.18 KXS21446.1 - 2.2e-09 37.1 0.5 1.1e-08 34.8 0.6 1.8 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF2207 PF09972.9 KXS21446.1 - 0.15 10.8 0.0 0.2 10.4 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4588 PF15251.6 KXS21447.1 - 0.018 14.8 0.1 0.018 14.8 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4588) Barttin PF15462.6 KXS21447.1 - 1.2 8.9 3.4 2.1 8.1 3.4 1.3 1 0 0 1 1 1 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) DUF3445 PF11927.8 KXS21449.1 - 4.9e-50 170.2 0.0 6.4e-50 169.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) MatE PF01554.18 KXS21450.1 - 1.7e-37 128.5 32.1 1.5e-20 73.5 7.4 2.8 3 1 0 3 3 3 2 MatE Polysacc_synt_C PF14667.6 KXS21450.1 - 0.00081 19.5 5.5 0.00081 19.5 5.5 3.7 3 1 2 5 5 5 1 Polysaccharide biosynthesis C-terminal domain Jiraiya PF15038.6 KXS21450.1 - 0.036 13.5 0.5 0.26 10.7 0.1 2.5 2 0 0 2 2 2 0 Jiraiya B277 PF17623.2 KXS21450.1 - 0.27 10.3 0.2 0.49 9.4 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF4200 PF13863.6 KXS21452.1 - 3e-26 92.2 31.9 5.3e-26 91.4 25.2 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4200) APG6_N PF17675.1 KXS21452.1 - 0.0084 16.6 3.4 0.0084 16.6 3.4 2.4 1 1 1 2 2 2 1 Apg6 coiled-coil region COG5 PF10392.9 KXS21452.1 - 0.044 14.0 0.8 0.044 14.0 0.8 2.5 2 1 0 2 2 2 0 Golgi transport complex subunit 5 DUF1664 PF07889.12 KXS21452.1 - 0.046 13.8 15.0 0.068 13.2 4.2 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) T2SSF PF00482.23 KXS21452.1 - 0.074 13.0 0.1 0.074 13.0 0.1 1.9 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F CHDCT2 PF08074.11 KXS21452.1 - 0.25 11.5 9.9 0.35 11.0 0.1 2.3 2 0 0 2 2 2 0 CHDCT2 (NUC038) domain eIF3_N PF09440.10 KXS21452.1 - 0.39 11.1 12.4 0.61 10.5 8.4 2.3 2 1 0 2 2 2 0 eIF3 subunit 6 N terminal domain Mod_r PF07200.13 KXS21452.1 - 0.52 10.4 23.0 0.74 9.9 0.7 3.1 1 1 2 3 3 3 0 Modifier of rudimentary (Mod(r)) protein HAP1_N PF04849.13 KXS21452.1 - 0.59 9.3 23.3 0.56 9.3 0.9 2.3 2 0 0 2 2 2 0 HAP1 N-terminal conserved region Peptidase_S46 PF10459.9 KXS21452.1 - 1 7.9 14.8 2.3 6.7 8.2 2.0 2 0 0 2 2 2 0 Peptidase S46 KxDL PF10241.9 KXS21452.1 - 3.2 8.1 20.8 2.4 8.5 0.4 3.5 2 1 1 3 3 3 0 Uncharacterized conserved protein DUF948 PF06103.11 KXS21452.1 - 3.2 8.1 5.1 6 7.2 0.2 2.7 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF1043 PF06295.12 KXS21452.1 - 6.4 6.8 17.0 0.99 9.4 0.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) DnaJ PF00226.31 KXS21453.1 - 2.9e-24 84.9 0.7 4.7e-24 84.3 0.7 1.3 1 0 0 1 1 1 1 DnaJ domain Gly-zipper_Omp PF13488.6 KXS21453.1 - 0.0038 17.2 17.9 0.0066 16.4 13.1 2.2 2 0 0 2 2 2 1 Glycine zipper Gly-zipper_YMGG PF13441.6 KXS21453.1 - 0.014 15.2 15.7 0.014 15.2 15.7 2.1 1 1 1 2 2 2 0 YMGG-like Gly-zipper Bacteriocin_IIc PF10439.9 KXS21453.1 - 0.015 15.4 8.6 0.015 15.4 8.6 2.0 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide MCM PF00493.23 KXS21453.1 - 0.12 11.4 0.0 0.17 10.9 0.0 1.1 1 0 0 1 1 1 0 MCM P-loop domain DUF456 PF04306.13 KXS21453.1 - 0.26 11.6 7.3 0.4 11.0 7.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF456) Phostensin_N PF13916.6 KXS21454.1 - 0.0048 17.2 0.3 0.0048 17.2 0.3 2.5 2 1 1 3 3 3 1 PP1-regulatory protein, Phostensin N-terminal DUF2839 PF10999.8 KXS21454.1 - 0.11 12.9 0.4 0.62 10.5 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2839) TIP49 PF06068.13 KXS21455.1 - 5.4e-160 532.3 0.4 5.4e-160 532.3 0.4 1.4 2 0 0 2 2 2 1 TIP49 P-loop domain TIP49_C PF17856.1 KXS21455.1 - 2e-27 95.1 1.2 4.5e-27 94.0 1.2 1.6 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 KXS21455.1 - 5.3e-09 36.6 2.2 1e-05 25.9 0.1 3.2 3 1 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KXS21455.1 - 1.8e-08 34.3 0.4 0.00037 20.3 0.1 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KXS21455.1 - 2.3e-06 27.7 0.2 0.0016 18.5 0.0 3.0 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) DnaB_C PF03796.15 KXS21455.1 - 4.9e-06 26.1 0.2 9.3e-06 25.2 0.2 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain Mg_chelatase PF01078.21 KXS21455.1 - 3.7e-05 23.2 1.2 0.0031 16.9 0.8 2.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 KXS21455.1 - 0.00025 21.5 0.1 0.0014 19.0 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain Sigma54_activat PF00158.26 KXS21455.1 - 0.0016 18.2 0.4 1.6 8.4 0.1 3.0 3 0 0 3 3 3 2 Sigma-54 interaction domain AAA_22 PF13401.6 KXS21455.1 - 0.0018 18.5 0.2 0.31 11.3 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.6 KXS21455.1 - 0.0022 18.3 8.4 0.016 15.6 3.7 3.2 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KXS21455.1 - 0.0069 16.5 0.0 0.018 15.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 KXS21455.1 - 0.0075 15.9 1.2 0.014 15.0 0.1 1.9 2 0 0 2 2 2 1 AAA domain ATPase PF06745.13 KXS21455.1 - 0.009 15.4 0.1 0.021 14.2 0.1 1.8 1 0 0 1 1 1 1 KaiC DUF1110 PF06533.12 KXS21455.1 - 0.024 14.6 0.1 0.31 11.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1110) Zeta_toxin PF06414.12 KXS21455.1 - 0.028 13.7 0.4 0.066 12.5 0.4 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_30 PF13604.6 KXS21455.1 - 0.038 13.7 0.6 0.93 9.2 0.3 2.4 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KXS21455.1 - 0.057 12.9 0.4 0.23 11.0 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF2075 PF09848.9 KXS21455.1 - 0.083 12.1 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_28 PF13521.6 KXS21455.1 - 0.13 12.5 1.8 0.21 11.8 0.0 2.2 3 0 0 3 3 2 0 AAA domain ResIII PF04851.15 KXS21455.1 - 0.13 12.2 1.3 4.6 7.2 1.3 2.5 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit TsaE PF02367.17 KXS21455.1 - 0.19 11.8 1.2 0.45 10.5 0.2 2.1 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF2969 PF11184.8 KXS21455.1 - 1.5 9.3 4.4 3.7 8.0 0.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2969) GLE1 PF07817.13 KXS21456.1 - 2.2e-55 187.6 0.0 3.4e-55 187.0 0.0 1.3 1 0 0 1 1 1 1 GLE1-like protein Methyltransf_32 PF13679.6 KXS21456.1 - 0.96 9.4 4.6 6.4 6.8 0.0 2.9 2 1 0 2 2 2 0 Methyltransferase domain TFIIA PF03153.13 KXS21456.1 - 1.7 8.5 13.6 3 7.8 13.6 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Vps54 PF07928.12 KXS21457.1 - 3.5e-46 157.0 1.0 1e-45 155.4 1.0 1.9 1 0 0 1 1 1 1 Vps54-like protein Vps54_N PF10475.9 KXS21457.1 - 1.1e-09 38.0 0.4 1.9e-08 34.0 0.0 2.5 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex DUF2451 PF10474.9 KXS21457.1 - 6.2e-06 26.2 0.2 1.6e-05 24.8 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) DUF3510 PF12022.8 KXS21457.1 - 0.021 15.2 0.4 0.11 12.9 0.4 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF3510) SAM_1 PF00536.30 KXS21459.1 - 0.0076 16.7 0.0 0.015 15.8 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KXS21459.1 - 0.011 15.9 0.0 0.023 14.8 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) DcpS_C PF11969.8 KXS21460.1 - 3.3e-30 104.9 1.3 3.3e-30 104.9 1.3 1.8 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.12 KXS21460.1 - 1.8e-21 76.9 0.0 3.5e-21 76.0 0.0 1.5 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal HIT PF01230.23 KXS21460.1 - 0.0054 17.4 2.0 0.012 16.3 2.0 1.5 1 0 0 1 1 1 1 HIT domain SNF2_N PF00176.23 KXS21461.1 - 2.3e-66 223.9 0.1 7e-65 219.0 0.0 2.4 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KXS21461.1 - 4e-21 75.4 0.0 1.5e-20 73.6 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXS21461.1 - 3.7e-08 33.5 0.0 1.3e-07 31.8 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KXS21461.1 - 0.01 15.1 0.0 0.01 15.1 0.0 1.8 2 0 0 2 2 2 0 ERCC3/RAD25/XPB C-terminal helicase DUF4810 PF16068.5 KXS21461.1 - 0.066 13.8 0.0 0.35 11.5 0.0 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4810) Peptidase_S15 PF02129.18 KXS21462.1 - 9e-13 48.4 0.0 9.6e-13 48.3 0.0 1.1 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.12 KXS21462.1 - 2.3e-10 39.6 0.3 1.8e-07 30.2 0.1 2.1 1 1 1 2 2 2 2 Acetyl xylan esterase (AXE1) Abhydrolase_6 PF12697.7 KXS21462.1 - 1e-07 32.8 0.0 1.2e-07 32.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXS21462.1 - 1.5e-06 28.1 0.0 1.8e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXS21462.1 - 4.2e-06 26.2 0.0 4.9e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KXS21462.1 - 0.00011 21.7 0.0 0.00017 21.1 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family BAAT_C PF08840.11 KXS21462.1 - 0.00014 21.9 0.0 0.00018 21.5 0.0 1.2 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Acyl_transf_2 PF02273.15 KXS21462.1 - 0.0062 15.8 0.0 0.008 15.5 0.0 1.1 1 0 0 1 1 1 1 Acyl transferase PAF-AH_p_II PF03403.13 KXS21462.1 - 0.0096 14.5 0.0 0.86 8.0 0.0 2.1 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II DNA_primase_S PF01896.19 KXS21462.1 - 0.088 12.8 0.0 0.13 12.3 0.0 1.3 1 1 0 1 1 1 0 DNA primase small subunit DLH PF01738.18 KXS21462.1 - 0.09 12.3 0.1 0.3 10.6 0.1 1.8 1 1 0 1 1 1 0 Dienelactone hydrolase family UPF0086 PF01868.16 KXS21463.1 - 3.5e-25 87.7 0.0 1.2e-24 86.1 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function UPF0086 DUF1748 PF08520.10 KXS21464.1 - 9.5e-15 54.3 0.0 1.1e-14 54.0 0.0 1.1 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) DEP PF00610.21 KXS21465.1 - 0.00015 21.8 0.0 0.00028 20.9 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DUF3915 PF13054.6 KXS21466.1 - 0.48 10.4 2.4 0.8 9.7 2.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) PCO_ADO PF07847.12 KXS21467.1 - 1.2e-12 47.7 0.1 1.7e-12 47.2 0.1 1.3 1 0 0 1 1 1 1 PCO_ADO ECH_1 PF00378.20 KXS21468.1 - 3.3e-36 124.9 0.0 3.7e-36 124.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXS21468.1 - 1.1e-15 58.0 0.0 1.3e-15 57.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase FAA_hydrolase PF01557.18 KXS21469.1 - 2.7e-65 220.1 0.0 3.7e-65 219.7 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Peroxin-3 PF04882.12 KXS21470.1 - 9.8e-71 239.1 0.0 6.9e-69 233.0 0.0 2.0 1 1 0 1 1 1 1 Peroxin-3 TetR_C_34 PF17929.1 KXS21470.1 - 0.022 14.8 4.0 0.16 12.1 0.1 2.4 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain DUF3180 PF11377.8 KXS21470.1 - 9.9 6.3 14.4 12 6.0 12.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3180) Ring_hydroxyl_A PF00848.19 KXS21474.1 - 3.1e-28 99.2 0.2 7.4e-28 98.0 0.2 1.6 1 1 0 1 1 1 1 Ring hydroxylating alpha subunit (catalytic domain) Prenylcys_lyase PF07156.14 KXS21475.1 - 5.4e-52 177.1 0.0 7.2e-52 176.7 0.0 1.1 1 0 0 1 1 1 1 Prenylcysteine lyase Amino_oxidase PF01593.24 KXS21475.1 - 3.4e-17 62.9 0.0 5.4e-17 62.2 0.0 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KXS21475.1 - 7.2e-14 51.8 0.4 1.3e-12 47.7 0.1 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KXS21475.1 - 1.4e-07 31.6 0.2 0.0047 16.9 0.1 2.6 3 0 0 3 3 3 2 FAD-NAD(P)-binding DAO PF01266.24 KXS21475.1 - 6.6e-06 25.9 0.6 0.0017 18.0 0.5 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXS21475.1 - 0.00052 19.3 0.1 0.012 14.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KXS21475.1 - 0.1 11.9 0.1 0.16 11.2 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain IMS PF00817.20 KXS21476.1 - 1.2e-41 142.1 0.0 2.2e-41 141.3 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family zf_UBZ PF18439.1 KXS21476.1 - 1.7e-13 49.9 0.0 4e-13 48.7 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger IMS_C PF11799.8 KXS21476.1 - 3.6e-11 43.8 0.0 9.2e-11 42.5 0.0 1.7 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 KXS21476.1 - 0.17 12.3 0.0 0.46 10.9 0.0 1.7 1 0 0 1 1 1 0 IMS family HHH motif peroxidase PF00141.23 KXS21477.1 - 1.7e-65 220.9 0.0 1.2e-46 159.2 0.0 2.9 2 1 0 2 2 2 2 Peroxidase DUF155 PF02582.14 KXS21478.1 - 6.2e-41 140.4 0.0 8.9e-41 139.9 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Rac1 PF09632.10 KXS21478.1 - 0.2 10.8 0.0 0.47 9.6 0.0 1.5 1 0 0 1 1 1 0 Rac1-binding domain Cas1_AcylT PF07779.12 KXS21479.1 - 1.3e-119 400.3 17.6 1.8e-119 399.7 17.6 1.1 1 0 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p PC-Esterase PF13839.6 KXS21479.1 - 0.004 17.0 0.0 0.0075 16.0 0.0 1.4 1 0 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p LRR_6 PF13516.6 KXS21480.1 - 7.1e-12 44.4 0.8 1.7 8.9 0.0 8.1 9 0 0 9 9 9 3 Leucine Rich repeat LRR_1 PF00560.33 KXS21480.1 - 1.4e-10 40.2 2.0 3.2 8.7 0.0 7.2 7 1 0 7 7 7 4 Leucine Rich Repeat LRR_4 PF12799.7 KXS21480.1 - 1.1e-09 38.4 0.0 0.023 15.1 0.0 5.0 4 2 1 5 5 5 3 Leucine Rich repeats (2 copies) F-box PF00646.33 KXS21480.1 - 1.2e-08 34.6 0.7 1.2e-08 34.6 0.7 2.6 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KXS21480.1 - 3.9e-05 23.5 0.1 0.0001 22.1 0.1 1.8 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.6 KXS21480.1 - 0.04 13.7 0.1 19 5.1 0.0 4.1 3 1 0 3 3 3 0 Leucine rich repeat F-box_4 PF15966.5 KXS21480.1 - 0.076 12.9 0.1 0.27 11.2 0.1 1.9 1 0 0 1 1 1 0 F-box TPR_2 PF07719.17 KXS21481.1 - 0.00057 19.8 0.4 0.033 14.3 0.1 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 KXS21481.1 - 0.0018 18.9 0.3 0.023 15.5 0.2 2.0 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 KXS21481.1 - 0.0037 17.0 0.1 0.12 12.2 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 KXS21481.1 - 0.019 15.1 0.1 0.024 14.7 0.1 1.2 1 0 0 1 1 1 0 Tetratricopeptide repeat FA_hydroxylase PF04116.13 KXS21482.1 - 6.4e-19 68.6 17.0 6.4e-19 68.6 17.0 1.7 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Cg6151-P PF10233.9 KXS21483.1 - 3.2e-28 98.3 12.3 4.1e-28 97.9 12.3 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P EI24 PF07264.11 KXS21483.1 - 0.013 15.8 8.0 0.031 14.5 8.2 1.6 1 1 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) Fer4_20 PF14691.6 KXS21483.1 - 0.035 13.9 0.0 0.049 13.4 0.0 1.2 1 0 0 1 1 1 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster DUF373 PF04123.13 KXS21483.1 - 0.44 9.9 2.6 0.59 9.5 2.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF373) Phage_holin_3_6 PF07332.11 KXS21483.1 - 0.73 9.9 13.6 0.42 10.7 2.8 2.2 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III DUF3810 PF12725.7 KXS21483.1 - 1.5 8.1 7.3 2 7.7 7.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) DUF2070 PF09843.9 KXS21483.1 - 2.5 6.3 6.7 2.8 6.1 6.7 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) PRA1 PF03208.19 KXS21483.1 - 2.9 7.5 9.6 6.2 6.4 9.7 1.5 1 1 0 1 1 1 0 PRA1 family protein Cg6151-P PF10233.9 KXS21484.1 - 3.5e-23 82.1 11.9 4.4e-23 81.7 11.9 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P TMEM72 PF16054.5 KXS21484.1 - 0.0012 18.6 9.9 0.002 17.9 9.9 1.3 1 1 0 1 1 1 1 Transmembrane protein family 72 Fer4_20 PF14691.6 KXS21484.1 - 0.012 15.3 0.1 0.017 14.9 0.1 1.1 1 0 0 1 1 1 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster TrbL PF04610.14 KXS21484.1 - 0.16 11.7 13.1 0.44 10.3 12.9 1.8 1 1 0 1 1 1 0 TrbL/VirB6 plasmid conjugal transfer protein MtrE PF04206.12 KXS21484.1 - 1.5 8.1 6.7 1.8 7.8 6.7 1.0 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit E PRA1 PF03208.19 KXS21484.1 - 2.3 7.8 9.6 3 7.5 9.6 1.2 1 0 0 1 1 1 0 PRA1 family protein DUF3784 PF12650.7 KXS21484.1 - 3.5 7.9 13.5 0.35 11.1 0.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) DUF3810 PF12725.7 KXS21484.1 - 6.8 5.9 6.9 11 5.2 7.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3810) Fungal_trans PF04082.18 KXS21485.1 - 3.5e-09 36.1 0.0 1.4e-08 34.1 0.0 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain AMP-binding PF00501.28 KXS21487.1 - 9e-49 166.2 0.0 1.2e-48 165.8 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXS21487.1 - 2e-08 35.1 0.1 3.5e-08 34.3 0.1 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Beta-lactamase PF00144.24 KXS21489.1 - 1.8e-22 80.0 0.0 4.8e-22 78.6 0.0 1.6 1 1 0 1 1 1 1 Beta-lactamase ADH_zinc_N PF00107.26 KXS21490.1 - 2.2e-28 98.8 0.9 4.3e-28 97.9 0.5 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXS21490.1 - 5.9e-28 96.9 1.6 5.9e-28 96.9 1.6 2.2 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KXS21490.1 - 3e-07 31.5 0.0 6.6e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KXS21490.1 - 5.4e-06 26.1 0.4 7.4e-06 25.6 0.4 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus Asp_decarbox PF02261.16 KXS21490.1 - 0.00073 19.5 0.0 0.0018 18.2 0.0 1.7 1 0 0 1 1 1 1 Aspartate decarboxylase TrkA_N PF02254.18 KXS21490.1 - 0.095 13.0 0.3 0.21 11.8 0.3 1.6 1 0 0 1 1 1 0 TrkA-N domain FMO-like PF00743.19 KXS21491.1 - 1.3e-07 30.5 0.0 2.6e-06 26.1 0.0 2.4 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KXS21491.1 - 1.6e-07 31.4 0.0 5.3e-07 29.8 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXS21491.1 - 3.5e-07 29.8 0.0 0.00049 19.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXS21491.1 - 6.7e-07 28.8 0.0 0.00022 20.5 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KXS21491.1 - 0.00072 19.2 0.1 0.16 11.5 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KXS21491.1 - 0.0019 17.5 0.0 0.11 11.8 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXS21491.1 - 0.0049 16.9 0.0 0.12 12.4 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding GIDA PF01134.22 KXS21491.1 - 0.15 11.1 0.0 1.3 8.0 0.0 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A Thi4 PF01946.17 KXS21491.1 - 0.17 11.1 0.0 2.7 7.2 0.0 2.1 2 0 0 2 2 2 0 Thi4 family CCDC92 PF14916.6 KXS21493.1 - 0.15 11.8 3.2 3.3 7.6 2.4 2.6 2 0 0 2 2 2 0 Coiled-coil domain of unknown function NBP1 PF08537.10 KXS21493.1 - 0.42 10.0 3.9 0.54 9.6 3.9 1.1 1 0 0 1 1 1 0 Fungal Nap binding protein NBP1 OmpH PF03938.14 KXS21493.1 - 1.6 9.1 7.3 2.3 8.6 7.3 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) CiPC PF15800.5 KXS21495.1 - 0.26 10.9 2.9 0.32 10.7 2.9 1.0 1 0 0 1 1 1 0 Clock interacting protein circadian bZIP_2 PF07716.15 KXS21496.1 - 0.0011 19.0 6.2 0.0011 19.0 6.2 2.2 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 KXS21496.1 - 0.0014 18.6 6.7 0.0014 18.6 6.7 2.5 3 0 0 3 3 3 1 bZIP transcription factor FMN_red PF03358.15 KXS21497.1 - 5.3e-21 75.0 0.0 6.5e-21 74.7 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 KXS21497.1 - 3.1e-06 27.0 0.0 4.3e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold Epimerase PF01370.21 KXS21497.1 - 0.0082 15.6 0.0 0.011 15.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Pantoate_ligase PF02569.15 KXS21498.1 - 3e-82 275.8 0.0 3.4e-82 275.6 0.0 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase OEP PF02321.18 KXS21498.1 - 0.12 12.2 0.5 0.19 11.5 0.5 1.2 1 0 0 1 1 1 0 Outer membrane efflux protein Proteasome PF00227.26 KXS21499.1 - 1.5e-58 197.4 0.9 1.9e-58 197.1 0.9 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KXS21499.1 - 5.1e-14 51.6 0.1 1.3e-13 50.4 0.1 1.8 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature SH3_1 PF00018.28 KXS21500.1 - 2e-16 59.3 0.2 1e-09 37.8 0.1 2.4 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 KXS21500.1 - 2.4e-13 49.7 0.7 1.3e-07 31.3 0.2 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.17 KXS21500.1 - 8.2e-08 31.8 0.0 0.00063 19.4 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain SPRY PF00622.28 KXS21501.1 - 0.0005 20.2 0.0 0.0012 18.9 0.0 1.6 1 0 0 1 1 1 1 SPRY domain CRAL_TRIO PF00650.20 KXS21502.1 - 6.1e-08 32.5 0.0 0.0001 22.1 0.0 2.3 2 0 0 2 2 2 2 CRAL/TRIO domain Sulfatase PF00884.23 KXS21503.1 - 7.5e-54 183.2 0.3 1.1e-53 182.6 0.3 1.2 1 0 0 1 1 1 1 Sulfatase DUF4976 PF16347.5 KXS21503.1 - 0.055 13.7 0.0 0.16 12.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4976) SNAD3 PF18749.1 KXS21503.1 - 0.19 10.8 0.0 0.33 10.1 0.0 1.3 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 3 ASCH PF04266.14 KXS21504.1 - 1.5e-15 57.7 0.2 1.8e-15 57.4 0.2 1.1 1 0 0 1 1 1 1 ASCH domain Ion_trans PF00520.31 KXS21505.1 - 4.8e-68 229.0 40.3 5.3e-33 114.3 20.4 4.2 4 0 0 4 4 4 4 Ion transport protein Selenoprotein_S PF06936.11 KXS21505.1 - 0.025 14.4 0.0 0.059 13.2 0.0 1.6 1 0 0 1 1 1 0 Selenoprotein S (SelS) PKD_channel PF08016.12 KXS21505.1 - 0.025 13.2 27.0 0.15 10.7 1.0 3.8 2 1 1 3 3 3 0 Polycystin cation channel GPHH PF16905.5 KXS21505.1 - 0.046 13.5 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 Voltage-dependent L-type calcium channel, IQ-associated IQ PF00612.27 KXS21505.1 - 4.2 7.4 5.0 3.2 7.8 1.8 2.4 2 0 0 2 2 2 0 IQ calmodulin-binding motif CBFD_NFYB_HMF PF00808.23 KXS21506.1 - 8e-10 38.9 0.1 9.5e-10 38.6 0.1 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone MFS_5 PF05631.14 KXS21507.1 - 5.6e-73 245.9 8.5 7.5e-73 245.5 8.5 1.2 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 KXS21507.1 - 6.5e-25 87.8 56.1 9.4e-22 77.4 29.7 3.8 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXS21507.1 - 6.6e-06 25.3 20.0 3.8e-05 22.7 1.3 2.5 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.7 KXS21507.1 - 8.9e-05 21.5 8.0 0.009 14.9 0.0 2.5 2 0 0 2 2 2 2 MFS_1 like family XPG_N PF00752.17 KXS21508.1 - 2.5e-32 111.4 0.0 6.5e-32 110.0 0.0 1.7 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I PF00867.18 KXS21508.1 - 2.4e-23 82.3 0.0 5.3e-23 81.2 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.7 KXS21508.1 - 0.00018 21.0 0.0 0.00054 19.5 0.0 1.7 1 1 0 1 1 1 1 XPG domain containing 5_3_exonuc PF01367.20 KXS21508.1 - 0.053 14.1 0.0 0.81 10.3 0.0 2.8 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold Lon_C PF05362.13 KXS21509.1 - 6.2e-69 231.6 0.0 1.2e-68 230.7 0.0 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 KXS21509.1 - 5.2e-28 98.4 1.7 8.8e-28 97.6 0.1 2.1 2 0 0 2 2 2 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 KXS21509.1 - 2.4e-23 83.0 0.0 7.2e-23 81.5 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.6 KXS21509.1 - 3.9e-06 26.7 0.0 9.8e-06 25.4 0.0 1.7 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_5 PF07728.14 KXS21509.1 - 8.8e-06 25.8 0.0 2e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KXS21509.1 - 3.2e-05 24.1 0.0 0.0001 22.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 KXS21509.1 - 7.4e-05 22.6 0.0 0.0004 20.2 0.0 2.3 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_PrkA PF08298.11 KXS21509.1 - 0.00019 20.5 0.0 0.00034 19.6 0.0 1.3 1 0 0 1 1 1 1 PrkA AAA domain AAA_22 PF13401.6 KXS21509.1 - 0.00019 21.7 0.1 0.0039 17.5 0.1 2.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KXS21509.1 - 0.0003 21.2 0.1 0.0013 19.2 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 KXS21509.1 - 0.0016 19.0 0.4 0.0098 16.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 KXS21509.1 - 0.0017 18.4 0.1 0.014 15.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 KXS21509.1 - 0.011 15.7 0.3 0.69 9.8 0.0 3.0 2 1 1 3 3 3 0 NTPase AAA_30 PF13604.6 KXS21509.1 - 0.012 15.4 0.2 0.16 11.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain SKI PF01202.22 KXS21509.1 - 0.03 14.4 0.3 0.1 12.7 0.0 2.0 2 0 0 2 2 2 0 Shikimate kinase RNA_helicase PF00910.22 KXS21509.1 - 0.038 14.4 0.0 0.096 13.1 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_3 PF07726.11 KXS21509.1 - 0.044 13.6 0.0 0.15 11.9 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 KXS21509.1 - 0.059 13.1 0.0 0.17 11.6 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein Phage_connect_1 PF05135.13 KXS21509.1 - 0.065 13.7 0.1 0.22 12.1 0.1 1.9 1 0 0 1 1 1 0 Phage gp6-like head-tail connector protein AAA_24 PF13479.6 KXS21509.1 - 0.079 12.7 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain KLRAQ PF10205.9 KXS21510.1 - 6.2e-17 61.7 7.5 6.2e-17 61.7 7.5 4.4 2 2 2 4 4 4 1 Predicted coiled-coil domain-containing protein WD-3 PF09765.9 KXS21510.1 - 0.14 11.4 11.5 0.01 15.2 4.4 2.4 2 0 0 2 2 2 0 WD-repeat region ATG16 PF08614.11 KXS21510.1 - 0.17 12.1 58.0 0.38 10.9 14.1 4.2 3 2 1 4 4 4 0 Autophagy protein 16 (ATG16) YtxH PF12732.7 KXS21510.1 - 4.5 7.9 11.4 0.37 11.4 0.4 4.0 3 1 0 3 3 3 0 YtxH-like protein ECH_1 PF00378.20 KXS21511.1 - 5.4e-57 193.0 0.0 6.2e-57 192.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXS21511.1 - 8.3e-30 104.4 0.0 6.4e-29 101.5 0.0 1.7 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase HicB_lk_antitox PF15919.5 KXS21511.1 - 0.19 11.9 0.0 0.29 11.2 0.0 1.3 1 0 0 1 1 1 0 HicB_like antitoxin of bacterial toxin-antitoxin system MRP-L28 PF09812.9 KXS21512.1 - 2.7e-10 40.6 0.7 2.9e-10 40.5 0.7 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 LD_cluster3 PF18180.1 KXS21512.1 - 0.11 12.1 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 SLOG cluster3 family TP_methylase PF00590.20 KXS21513.1 - 4.9e-17 62.6 0.1 7.5e-17 62.0 0.1 1.4 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases XRN1_D2_D3 PF18334.1 KXS21514.1 - 0.00096 19.3 0.0 0.0024 18.0 0.0 1.7 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D2/D3 domain DUF4881 PF16222.5 KXS21514.1 - 0.023 14.6 0.0 0.025 14.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4881) GerE PF00196.19 KXS21514.1 - 0.03 13.9 0.0 0.18 11.4 0.0 2.1 3 0 0 3 3 3 0 Bacterial regulatory proteins, luxR family DUF3875 PF12991.7 KXS21514.1 - 0.068 13.1 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3875) CBM_21 PF03370.13 KXS21515.1 - 4.9e-24 84.7 0.0 7.8e-24 84.0 0.0 1.3 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 KXS21515.1 - 3.1e-08 34.1 0.2 6.3e-08 33.1 0.2 1.5 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) PIN_4 PF13638.6 KXS21517.1 - 4.7e-15 56.0 0.0 8.4e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 PIN domain EST1_DNA_bind PF10373.9 KXS21517.1 - 4.4e-11 42.8 0.0 1.5e-10 41.1 0.0 1.8 1 1 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.9 KXS21517.1 - 0.0057 17.3 0.0 0.088 13.4 0.0 2.4 1 1 0 1 1 1 1 Telomerase activating protein Est1 RabGAP-TBC PF00566.18 KXS21518.1 - 1.2e-35 123.2 1.7 1.7e-35 122.6 1.7 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Snf7 PF03357.21 KXS21519.1 - 1.1e-46 158.6 9.1 1.1e-46 158.6 9.1 1.6 2 0 0 2 2 2 1 Snf7 DUF2586 PF10758.9 KXS21519.1 - 0.027 13.7 1.1 0.031 13.5 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2586) ECH_1 PF00378.20 KXS21520.1 - 2.7e-40 138.3 0.0 6.3e-39 133.8 0.0 2.0 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXS21520.1 - 3.2e-20 72.9 0.0 4.2e-20 72.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase DC_STAMP PF07782.13 KXS21521.1 - 0.012 15.5 0.0 0.013 15.3 0.0 1.1 1 0 0 1 1 1 0 DC-STAMP-like protein Acetyltransf_7 PF13508.7 KXS21525.1 - 9.8e-06 25.9 0.1 4.2e-05 23.9 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KXS21525.1 - 3.5e-05 23.8 0.0 7.5e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXS21525.1 - 4.2e-05 23.7 0.0 8.3e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Glyco_hydro_26 PF02156.15 KXS21526.1 - 2.5e-11 43.6 0.0 3.7e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 26 AP_endonuc_2 PF01261.24 KXS21526.1 - 0.16 11.4 0.0 0.25 10.8 0.0 1.2 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Aldo_ket_red PF00248.21 KXS21527.1 - 4.3e-39 134.5 0.0 4e-37 128.0 0.0 2.2 1 1 0 1 1 1 1 Aldo/keto reductase family RL10P_insert PF17777.1 KXS21528.1 - 2.2e-21 75.6 0.2 4.6e-21 74.6 0.2 1.6 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 KXS21528.1 - 9.1e-20 70.7 0.1 1.8e-19 69.7 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_60s PF00428.19 KXS21528.1 - 1.1e-17 64.3 11.9 1.6e-14 54.2 8.7 3.0 3 0 0 3 3 3 2 60s Acidic ribosomal protein Pkinase PF00069.25 KXS21529.1 - 9.6e-73 244.8 0.0 1.3e-72 244.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS21529.1 - 6.5e-33 114.1 0.0 9.2e-33 113.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 KXS21529.1 - 6.5e-14 52.4 2.7 4.1e-13 49.8 1.6 2.4 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.6 KXS21529.1 - 1.1e-05 24.9 0.0 3.1e-05 23.5 0.0 1.7 1 1 1 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 KXS21529.1 - 1.3e-05 24.3 0.1 2.1e-05 23.6 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 KXS21529.1 - 0.0029 17.3 0.0 0.13 11.8 0.0 2.2 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 KXS21529.1 - 0.08 12.3 0.1 0.28 10.5 0.1 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF959 PF06121.14 KXS21529.1 - 1.1 9.5 5.4 2.4 8.4 0.0 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF959) RhoGEF PF00621.20 KXS21530.1 - 2.1e-08 34.6 0.0 2.7e-08 34.3 0.0 1.1 1 0 0 1 1 1 1 RhoGEF domain SSP160 PF06933.11 KXS21530.1 - 0.93 7.6 5.8 1.6 6.9 5.8 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 BAR PF03114.18 KXS21531.1 - 1.6e-07 31.2 0.1 2.1e-07 30.8 0.1 1.2 1 0 0 1 1 1 1 BAR domain CytochromB561_N PF09786.9 KXS21531.1 - 0.061 12.3 1.6 0.083 11.9 1.6 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal DUF1940 PF09155.10 KXS21531.1 - 0.14 12.2 0.1 0.23 11.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1940) Helicase_C PF00271.31 KXS21532.1 - 1.6e-26 92.8 0.0 5.6e-26 91.1 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KXS21532.1 - 4.9e-09 36.2 0.0 2.6e-08 33.8 0.0 2.2 2 1 0 2 2 2 1 DEAD/DEAH box helicase HEM4 PF02602.15 KXS21532.1 - 0.13 11.6 0.0 0.25 10.6 0.0 1.4 1 0 0 1 1 1 0 Uroporphyrinogen-III synthase HemD LPMO_10 PF03067.15 KXS21534.1 - 0.0027 18.4 0.0 0.026 15.2 0.0 2.0 1 1 1 2 2 2 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading PhrC_PhrF PF11131.8 KXS21534.1 - 0.09 12.4 0.7 0.22 11.1 0.7 1.7 1 0 0 1 1 1 0 Rap-phr extracellular signalling RRM_1 PF00076.22 KXS21538.1 - 5.7e-85 279.1 2.9 1.9e-20 72.5 0.1 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 KXS21538.1 - 1.2e-27 95.8 0.1 6.4e-27 93.5 0.2 2.2 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.6 KXS21538.1 - 1.5e-14 53.6 0.3 0.0029 17.2 0.0 4.2 1 1 3 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KXS21538.1 - 2.5e-07 30.6 0.6 2.3 8.3 0.0 4.3 4 0 0 4 4 4 3 Nup53/35/40-type RNA recognition motif DUF4523 PF15023.6 KXS21538.1 - 1.1e-05 25.3 0.0 3.8 7.3 0.0 4.1 2 1 1 4 4 4 2 Protein of unknown function (DUF4523) Limkain-b1 PF11608.8 KXS21538.1 - 2.4e-05 24.3 2.1 1.1 9.3 0.2 4.0 4 0 0 4 4 4 2 Limkain b1 RRM_7 PF16367.5 KXS21538.1 - 7.3e-05 22.8 0.2 3.8 7.7 0.0 4.8 4 1 0 4 4 4 1 RNA recognition motif RRM_3 PF08777.11 KXS21538.1 - 0.0029 17.6 7.4 0.8 9.8 0.0 4.0 3 1 1 4 4 4 1 RNA binding motif OB_RNB PF08206.11 KXS21538.1 - 0.0032 17.1 0.5 7.4 6.3 0.0 3.4 3 0 0 3 3 3 2 Ribonuclease B OB domain YflT PF11181.8 KXS21538.1 - 0.012 16.1 3.5 0.69 10.5 2.8 2.5 2 0 0 2 2 2 0 Heat induced stress protein YflT SET_assoc PF11767.8 KXS21538.1 - 0.13 11.9 0.1 11 5.8 0.0 3.2 4 0 0 4 4 4 0 Histone lysine methyltransferase SET associated KASH_CCD PF14662.6 KXS21538.1 - 1.5 8.6 7.2 0.17 11.7 1.2 2.1 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH ABC_tran PF00005.27 KXS21539.1 - 1.1e-21 77.7 0.0 1.8e-21 77.1 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 KXS21539.1 - 8.6e-18 64.5 13.8 8.6e-18 64.5 13.8 1.8 2 0 0 2 2 2 1 ABC-2 type transporter RsgA_GTPase PF03193.16 KXS21539.1 - 0.003 17.5 0.4 0.0055 16.6 0.4 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_21 PF13304.6 KXS21539.1 - 0.15 11.8 0.2 9.1 6.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF87 PF01935.17 KXS21539.1 - 0.23 11.5 1.9 0.42 10.7 0.5 1.9 2 0 0 2 2 2 0 Helicase HerA, central domain Rpr2 PF04032.16 KXS21540.1 - 2e-14 53.6 0.0 3.2e-13 49.8 0.0 2.6 1 1 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain DUF4769 PF15992.5 KXS21540.1 - 0.14 12.0 1.1 0.32 10.8 1.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4769) DUF3323 PF11796.8 KXS21540.1 - 0.17 11.8 5.4 0.63 9.9 3.2 2.1 2 0 0 2 2 2 0 Protein of unknown function N-terminus (DUF3323) SDF PF00375.18 KXS21541.1 - 7.7e-96 321.5 32.3 9e-96 321.3 32.3 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family Ank_4 PF13637.6 KXS21542.1 - 8.7e-20 70.8 3.8 0.0019 18.8 0.1 7.3 4 2 4 8 8 8 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXS21542.1 - 1.2e-18 67.5 0.1 2.5e-05 24.8 0.0 4.6 2 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXS21542.1 - 2.2e-16 58.3 1.0 0.011 16.2 0.0 7.8 8 0 0 8 8 8 3 Ankyrin repeat Ank PF00023.30 KXS21542.1 - 1.7e-11 44.0 4.4 0.51 10.9 0.0 7.4 6 1 0 7 7 7 3 Ankyrin repeat Ank_5 PF13857.6 KXS21542.1 - 1.8e-09 37.6 7.9 0.075 13.4 0.4 6.9 6 3 2 8 8 8 4 Ankyrin repeats (many copies) WD40 PF00400.32 KXS21543.1 - 2.9e-12 46.9 14.7 0.0036 18.1 0.0 7.4 8 0 0 8 8 8 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXS21543.1 - 0.00041 20.6 0.0 1.8 8.9 0.0 5.5 5 2 1 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain bZIP_1 PF00170.21 KXS21544.1 - 9.3e-09 35.3 9.3 1.6e-08 34.6 9.3 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KXS21544.1 - 0.0029 17.7 9.2 0.0054 16.8 9.2 1.5 1 0 0 1 1 1 1 Basic region leucine zipper DivIC PF04977.15 KXS21544.1 - 0.2 11.5 2.0 0.36 10.6 2.0 1.5 1 0 0 1 1 1 0 Septum formation initiator bZIP_Maf PF03131.17 KXS21544.1 - 0.21 12.1 8.5 0.38 11.3 8.5 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor TMCO5 PF14992.6 KXS21544.1 - 1.5 8.3 5.6 2.5 7.6 5.6 1.3 1 1 0 1 1 1 0 TMCO5 family Spt5_N PF11942.8 KXS21544.1 - 1.9 9.5 11.6 3.2 8.8 11.6 1.3 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal EF-hand_1 PF00036.32 KXS21545.1 - 2.2e-13 48.7 12.0 0.00065 19.1 0.5 4.1 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 KXS21545.1 - 1.3e-12 46.6 8.7 0.0029 17.4 0.7 3.9 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.6 KXS21545.1 - 1.4e-12 47.9 7.0 8.2e-10 39.0 0.6 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 KXS21545.1 - 5e-10 39.1 8.7 1.6e-05 24.7 0.7 3.3 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 KXS21545.1 - 1.3e-09 37.1 8.7 0.0032 16.9 0.0 3.7 3 0 0 3 3 3 3 EF hand EF-hand_4 PF12763.7 KXS21545.1 - 1.1 9.3 4.5 16 5.5 0.2 3.0 1 1 2 3 3 3 0 Cytoskeletal-regulatory complex EF hand CAP_GLY PF01302.25 KXS21546.1 - 3.9e-14 52.4 0.0 1e-13 51.1 0.0 1.7 1 0 0 1 1 1 1 CAP-Gly domain LRR_8 PF13855.6 KXS21546.1 - 3.2e-12 46.0 8.6 5.5e-06 26.0 1.0 4.1 4 1 0 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 KXS21546.1 - 1.8e-10 40.9 2.6 0.0087 16.5 0.1 4.8 3 1 1 5 5 5 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KXS21546.1 - 5.5e-07 29.1 2.1 21 5.5 0.2 6.5 6 0 0 6 6 6 2 Leucine Rich repeat LRR_9 PF14580.6 KXS21546.1 - 0.00012 21.6 0.1 0.58 9.6 0.0 3.8 3 1 0 3 3 3 1 Leucine-rich repeat SCP_3 PF17844.1 KXS21546.1 - 0.044 13.6 0.2 0.11 12.3 0.2 1.6 1 0 0 1 1 1 0 Bacterial SCP ortholog LRR_1 PF00560.33 KXS21546.1 - 0.14 12.8 12.8 1.9 9.3 0.6 5.3 5 1 0 5 5 5 0 Leucine Rich Repeat DUF4880 PF16220.5 KXS21546.1 - 0.38 10.7 2.3 0.41 10.6 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4880) CHCH PF06747.13 KXS21548.1 - 1.8e-06 27.9 3.6 2.4e-06 27.5 3.6 1.2 1 0 0 1 1 1 1 CHCH domain TIP120 PF08623.10 KXS21550.1 - 4.3e-54 182.8 1.9 4.8e-52 176.1 0.0 4.5 4 0 0 4 4 4 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.6 KXS21550.1 - 2.1e-13 50.4 38.0 0.017 15.5 0.3 9.8 7 4 2 10 10 9 4 HEAT repeats HEAT PF02985.22 KXS21550.1 - 1.4e-12 46.7 27.7 0.18 12.1 0.1 12.7 14 0 0 14 14 11 3 HEAT repeat HEAT_EZ PF13513.6 KXS21550.1 - 2.1e-08 34.5 38.0 0.31 11.6 0.0 11.1 10 1 0 10 10 10 4 HEAT-like repeat Adaptin_N PF01602.20 KXS21550.1 - 2.2e-08 33.1 7.1 0.084 11.4 0.0 5.8 5 2 1 6 6 6 3 Adaptin N terminal region CLASP_N PF12348.8 KXS21550.1 - 1.1e-06 28.4 0.7 3.4 7.2 0.0 5.6 6 0 0 6 6 6 1 CLASP N terminal Cnd1 PF12717.7 KXS21550.1 - 3e-06 27.4 3.6 2.7 8.0 0.1 6.1 5 1 0 6 6 6 2 non-SMC mitotic condensation complex subunit 1 UME PF08064.13 KXS21550.1 - 7.7e-05 22.5 0.3 4.7 7.2 0.0 5.0 4 1 1 5 5 5 1 UME (NUC010) domain Tti2 PF10521.9 KXS21550.1 - 0.0003 20.4 3.3 6.2 6.3 0.0 5.3 4 1 2 6 6 6 2 Tti2 family MMS19_C PF12460.8 KXS21550.1 - 0.00041 19.6 13.0 0.46 9.6 0.1 5.4 5 1 0 5 5 5 3 RNAPII transcription regulator C-terminal Arm PF00514.23 KXS21550.1 - 0.0024 17.9 14.7 1.6 8.9 0.1 7.8 8 0 0 8 8 8 2 Armadillo/beta-catenin-like repeat DRIM PF07539.12 KXS21550.1 - 0.0026 16.2 3.4 2.9 6.1 0.0 4.3 3 1 1 4 4 4 2 Down-regulated in metastasis Vac14_Fab1_bd PF12755.7 KXS21550.1 - 0.014 15.9 3.6 16 6.2 0.1 5.8 7 0 0 7 7 5 0 Vacuolar 14 Fab1-binding region Sec7_N PF12783.7 KXS21550.1 - 0.025 14.5 1.6 3 7.8 0.0 4.3 5 0 0 5 5 4 0 Guanine nucleotide exchange factor in Golgi transport N-terminal RIX1 PF08167.12 KXS21550.1 - 0.036 13.8 3.8 0.16 11.7 0.1 4.0 6 0 0 6 6 6 0 rRNA processing/ribosome biogenesis API5 PF05918.11 KXS21550.1 - 0.075 11.8 0.4 1.8 7.3 0.5 2.8 3 0 0 3 3 3 0 Apoptosis inhibitory protein 5 (API5) Cnd3 PF12719.7 KXS21550.1 - 0.082 12.1 0.1 3.1 6.9 0.0 3.5 3 1 0 3 3 3 0 Nuclear condensing complex subunits, C-term domain EH_Signature PF15611.6 KXS21550.1 - 0.11 11.8 0.6 0.53 9.6 0.3 2.1 1 1 1 2 2 2 0 EH_Signature domain DNA_pol_phi PF04931.13 KXS21550.1 - 0.19 9.8 8.7 0.071 11.2 5.0 1.9 2 0 0 2 2 2 0 DNA polymerase phi V-ATPase_H_C PF11698.8 KXS21550.1 - 0.19 11.8 2.0 58 3.8 0.1 4.6 5 0 0 5 5 5 0 V-ATPase subunit H RICTOR_N PF14664.6 KXS21550.1 - 0.73 8.7 3.8 6.8 5.6 0.1 3.2 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR, N-term DUF4449 PF14613.6 KXS21551.1 - 3.5e-11 43.5 0.0 7e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4449) Glyco_hydro_47 PF01532.20 KXS21552.1 - 3.6e-118 395.4 0.0 7.5e-58 196.5 0.0 3.0 2 1 0 2 2 2 2 Glycosyl hydrolase family 47 RRM_1 PF00076.22 KXS21553.1 - 3.9e-17 61.8 0.0 6e-17 61.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KXS21553.1 - 1.6e-07 31.0 0.0 1.7e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Acyltransferase PF01553.21 KXS21554.1 - 1.9e-22 79.3 0.0 3.1e-22 78.6 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 KXS21554.1 - 1.4e-08 34.7 0.2 0.00015 21.8 0.1 2.5 2 0 0 2 2 2 2 Acyltransferase C-terminus DUF5614 PF18474.1 KXS21555.1 - 5.6e-10 38.9 0.0 3.3e-08 33.1 0.0 2.2 2 0 0 2 2 2 2 Family of unknown function (DUF5614) TROVE PF05731.11 KXS21556.1 - 3.5e-46 158.2 0.0 3.4e-43 148.3 0.0 2.8 1 1 0 1 1 1 1 TROVE domain MFS_1 PF07690.16 KXS21557.1 - 2.5e-14 53.0 27.4 2.5e-14 53.0 27.4 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 KXS21557.1 - 6.4e-09 35.7 12.5 1e-07 31.8 3.5 2.6 3 0 0 3 3 3 2 Ion channel regulatory protein UNC-93 DUF2208 PF09973.9 KXS21557.1 - 3.7 7.1 4.6 14 5.2 0.0 2.7 3 0 0 3 3 3 0 Predicted membrane protein (DUF2208) SH3_9 PF14604.6 KXS21558.1 - 2.1e-16 59.5 0.2 4.2e-08 32.9 0.0 2.7 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 KXS21558.1 - 1.6e-10 40.4 0.0 0.00011 21.7 0.0 2.6 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 KXS21558.1 - 0.0003 20.4 0.0 0.45 10.2 0.0 2.7 2 0 0 2 2 2 2 Variant SH3 domain Na_H_Exchanger PF00999.21 KXS21559.1 - 2.1e-67 227.6 33.3 2.6e-67 227.3 33.3 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF4293 PF14126.6 KXS21559.1 - 0.44 10.8 0.1 0.44 10.8 0.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4293) CPP1-like PF11833.8 KXS21559.1 - 2.4 7.8 4.7 14 5.3 0.2 2.9 3 0 0 3 3 3 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Tubulin-binding PF00418.19 KXS21560.1 - 6.1e-23 80.5 24.8 4.2e-09 36.2 3.1 5.0 4 1 0 4 4 4 4 Tau and MAP protein, tubulin-binding repeat Aldedh PF00171.22 KXS21561.1 - 1.5e-145 485.3 3.6 1.7e-145 485.1 3.6 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1542 PF07564.11 KXS21561.1 - 0.011 15.8 0.4 0.033 14.3 0.4 1.8 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1542) DUF3692 PF12469.8 KXS21561.1 - 0.015 15.5 0.3 0.055 13.7 0.0 1.9 2 0 0 2 2 2 0 CRISPR-associated protein BING4CT PF08149.11 KXS21562.1 - 0.0066 16.2 0.9 0.031 14.1 0.1 2.6 2 0 0 2 2 2 1 BING4CT (NUC141) domain SHE3 PF17078.5 KXS21562.1 - 0.19 11.4 38.8 1.6 8.4 25.8 2.4 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 Spc7 PF08317.11 KXS21562.1 - 1.5 7.7 49.7 0.5 9.2 22.3 3.3 1 1 2 3 3 3 0 Spc7 kinetochore protein ATG16 PF08614.11 KXS21562.1 - 2.5 8.3 54.0 0.032 14.5 8.2 4.1 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) Fez1 PF06818.15 KXS21562.1 - 8.8 6.7 45.6 1.2 9.6 2.1 3.7 1 1 2 3 3 3 0 Fez1 TMF_TATA_bd PF12325.8 KXS21563.1 - 0.0013 19.0 11.6 0.0013 19.0 11.6 5.0 1 1 4 5 5 5 1 TATA element modulatory factor 1 TATA binding Spc29 PF17082.5 KXS21563.1 - 0.25 11.1 14.6 0.91 9.3 1.7 3.0 1 1 1 2 2 2 0 Spindle Pole Component 29 Pox_A_type_inc PF04508.12 KXS21563.1 - 0.33 10.9 10.6 0.57 10.1 0.1 4.9 5 0 0 5 5 5 0 Viral A-type inclusion protein repeat MAD PF05557.13 KXS21563.1 - 0.35 9.2 36.4 0.51 8.6 12.9 2.8 1 1 1 2 2 2 0 Mitotic checkpoint protein HOOK PF05622.12 KXS21563.1 - 0.42 8.7 34.1 4.3 5.4 33.7 2.1 1 1 0 1 1 1 0 HOOK protein FdhD-NarQ PF02634.15 KXS21563.1 - 1.4 8.5 8.5 3.4 7.3 1.7 2.4 1 1 1 2 2 2 0 FdhD/NarQ family BLOC1_2 PF10046.9 KXS21563.1 - 1.5 9.2 17.5 1.2 9.4 3.0 4.4 2 1 2 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TPD52 PF04201.15 KXS21563.1 - 1.6 8.4 24.0 0.077 12.6 3.0 4.0 1 1 3 4 4 4 0 Tumour protein D52 family PKcGMP_CC PF16808.5 KXS21563.1 - 2.1 8.3 15.2 7.5 6.5 0.8 4.5 2 1 2 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase HAUS2 PF15003.6 KXS21563.1 - 2.1 8.1 13.0 0.03 14.0 3.8 2.5 2 2 0 2 2 2 0 HAUS augmin-like complex subunit 2 CorA PF01544.18 KXS21563.1 - 2.2 7.5 14.6 0.19 11.0 6.7 2.3 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein Shugoshin_N PF07558.11 KXS21563.1 - 2.3 8.1 5.8 12 5.8 0.1 3.4 4 0 0 4 4 4 0 Shugoshin N-terminal coiled-coil region GAS PF13851.6 KXS21563.1 - 2.6 7.4 35.0 0.12 11.7 10.1 3.7 1 1 4 5 5 5 0 Growth-arrest specific micro-tubule binding DUF5082 PF16888.5 KXS21563.1 - 2.6 8.3 22.0 0.11 12.7 8.8 3.5 3 2 0 3 3 3 0 Domain of unknown function (DUF5082) DUF3450 PF11932.8 KXS21563.1 - 3.6 6.8 30.6 2.3 7.4 6.6 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) V_ATPase_I PF01496.19 KXS21563.1 - 5.2 4.8 16.5 9.2 4.0 16.5 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SlyX PF04102.12 KXS21563.1 - 5.4 7.7 32.4 2.2 8.9 4.0 6.0 3 2 3 6 6 6 0 SlyX NPV_P10 PF05531.12 KXS21563.1 - 5.8 7.5 9.1 0.78 10.2 0.8 3.3 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF4472 PF14739.6 KXS21563.1 - 6.8 7.5 29.7 0.22 12.2 7.7 4.2 1 1 4 5 5 5 0 Domain of unknown function (DUF4472) ZZ PF00569.17 KXS21564.1 - 2.8e-19 68.6 20.2 1.4e-09 37.6 6.2 2.3 2 0 0 2 2 2 2 Zinc finger, ZZ type PB1 PF00564.24 KXS21564.1 - 9.5e-11 41.5 0.0 1.7e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 PB1 domain C1_2 PF03107.16 KXS21564.1 - 0.014 15.7 16.6 0.061 13.6 4.7 2.6 2 0 0 2 2 2 0 C1 domain DUF1521 PF07481.11 KXS21564.1 - 0.068 13.2 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1521) DUF3402 PF11882.8 KXS21564.1 - 0.068 12.3 0.5 0.11 11.6 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3402) CGGC PF08821.11 KXS21564.1 - 1.4 9.2 7.1 0.32 11.2 3.5 1.8 2 0 0 2 2 2 0 CGGC domain RR_TM4-6 PF06459.12 KXS21564.1 - 1.4 8.7 6.7 2.2 8.0 6.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SWM_repeat PF13753.6 KXS21564.1 - 1.5 9.0 3.9 14 5.9 0.2 2.8 2 1 0 2 2 2 0 Putative flagellar system-associated repeat DUF572 PF04502.13 KXS21564.1 - 9.5 5.7 8.0 20 4.6 8.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF572) ECH_1 PF00378.20 KXS21565.1 - 1.2e-27 96.8 0.0 1.7e-27 96.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXS21565.1 - 6.4e-17 62.1 0.0 7.2e-17 61.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Pkinase_Tyr PF07714.17 KXS21568.1 - 6.9e-59 199.2 0.0 5.6e-53 179.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXS21568.1 - 3.9e-51 173.9 0.0 2.5e-50 171.3 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.23 KXS21568.1 - 0.059 13.3 0.4 0.28 11.1 0.0 2.1 2 1 0 2 2 2 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 KXS21569.1 - 1.2e-60 205.0 0.0 6.6e-55 186.2 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXS21569.1 - 2e-53 181.5 0.0 9.5e-52 176.0 0.0 2.4 2 1 0 2 2 2 1 Protein kinase domain APH PF01636.23 KXS21569.1 - 0.073 13.0 0.5 0.34 10.8 0.0 2.2 2 1 0 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXS21569.1 - 0.16 10.7 0.0 0.27 10.0 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 KXS21569.1 - 0.19 10.6 0.0 0.37 9.7 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain FA_desaturase PF00487.24 KXS21570.1 - 1.1e-25 90.9 31.3 3e-25 89.5 31.3 1.7 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 KXS21570.1 - 0.00013 22.1 0.0 0.00025 21.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) RNA_pol_Rpb1_R PF05001.13 KXS21571.1 - 0.12 12.8 6.9 0.4 11.1 6.9 2.0 1 1 0 1 1 1 0 RNA polymerase Rpb1 C-terminal repeat Glycos_transf_1 PF00534.20 KXS21573.1 - 1.4e-21 76.8 0.0 3.2e-21 75.6 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KXS21573.1 - 2.4e-21 76.5 0.0 4.2e-21 75.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KXS21573.1 - 7.3e-14 52.1 0.2 4.2e-13 49.6 0.2 2.1 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 KXS21573.1 - 6.1e-06 26.8 0.3 2.4e-05 24.9 0.3 1.9 1 1 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 KXS21573.1 - 0.014 15.8 0.0 0.036 14.5 0.0 1.7 2 0 0 2 2 2 0 Glycosyl transferases group 1 Methyltransf_16 PF10294.9 KXS21575.1 - 9.1e-09 35.3 0.0 0.00027 20.7 0.0 2.2 2 0 0 2 2 2 2 Lysine methyltransferase Methyltransf_23 PF13489.6 KXS21575.1 - 0.0031 17.4 0.0 0.0051 16.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXS21575.1 - 0.011 15.5 0.0 0.068 13.0 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_25 PF13649.6 KXS21575.1 - 0.15 12.8 0.0 2.8 8.7 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase domain tRNA-synt_1 PF00133.22 KXS21576.1 - 5e-227 754.9 0.0 7.1e-227 754.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KXS21576.1 - 2.1e-24 86.2 0.0 6.9e-24 84.5 0.0 1.9 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KXS21576.1 - 7.2e-13 48.0 1.1 0.0011 17.9 0.2 3.7 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 KXS21576.1 - 0.035 13.4 0.0 0.077 12.3 0.0 1.5 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain Peptidase_M48_N PF16491.5 KXS21577.1 - 8.1e-60 201.8 3.9 2.3e-59 200.4 3.9 1.7 1 1 0 1 1 1 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 KXS21577.1 - 1.1e-44 152.6 0.0 1.7e-44 152.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M48 DUF2268 PF10026.9 KXS21577.1 - 0.019 14.6 0.0 0.032 13.8 0.0 1.3 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) SprT-like PF10263.9 KXS21577.1 - 0.079 12.8 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 SprT-like family Peptidase_M56 PF05569.11 KXS21577.1 - 0.76 8.9 3.4 0.41 9.8 0.8 1.8 2 0 0 2 2 2 0 BlaR1 peptidase M56 SNARE PF05739.19 KXS21578.1 - 3.8e-10 39.6 0.7 9.6e-10 38.3 0.7 1.7 1 0 0 1 1 1 1 SNARE domain SlyX PF04102.12 KXS21578.1 - 0.00034 21.2 1.4 0.63 10.7 0.0 2.8 2 0 0 2 2 2 2 SlyX Syntaxin PF00804.25 KXS21578.1 - 0.0023 17.6 0.5 5.1 6.7 0.0 2.6 2 1 0 2 2 2 2 Syntaxin DNA_pol3_chi PF04364.13 KXS21578.1 - 0.035 14.3 0.2 0.088 13.0 0.0 1.7 2 0 0 2 2 2 0 DNA polymerase III chi subunit, HolC NPV_P10 PF05531.12 KXS21578.1 - 0.038 14.4 2.2 0.4 11.2 0.0 3.0 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein Syntaxin-5_N PF11416.8 KXS21578.1 - 0.056 12.7 1.5 0.089 12.1 0.1 2.1 2 0 0 2 2 2 0 Syntaxin-5 N-terminal, Sly1p-binding domain DUF16 PF01519.16 KXS21578.1 - 0.13 12.8 0.2 0.64 10.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function DUF16 Med11 PF10280.9 KXS21578.1 - 0.23 11.9 3.3 0.98 9.9 0.4 3.0 3 1 0 3 3 3 0 Mediator complex protein KxDL PF10241.9 KXS21578.1 - 0.45 10.8 4.1 0.57 10.5 0.5 2.7 3 0 0 3 3 3 0 Uncharacterized conserved protein Syntaxin-18_N PF10496.9 KXS21578.1 - 0.54 10.5 2.4 0.78 10.0 0.1 2.5 3 0 0 3 3 3 0 SNARE-complex protein Syntaxin-18 N-terminus DUF5082 PF16888.5 KXS21578.1 - 1.1 9.6 4.7 62 3.9 0.1 3.5 2 1 1 3 3 3 0 Domain of unknown function (DUF5082) DASH_Spc19 PF08287.11 KXS21578.1 - 1.4 8.8 8.0 1 9.3 0.7 2.6 2 1 1 3 3 3 0 Spc19 Flavodoxin_5 PF12724.7 KXS21579.1 - 2.7e-08 34.2 0.0 3.7e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin domain Flavodoxin_1 PF00258.25 KXS21579.1 - 0.0067 16.7 0.0 0.9 9.7 0.0 2.3 2 0 0 2 2 2 2 Flavodoxin DUF2796 PF10986.8 KXS21580.1 - 0.023 14.6 3.6 0.034 14.1 3.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) DUF2530 PF10745.9 KXS21580.1 - 0.22 11.8 2.1 0.38 11.0 1.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2530) DUF1772 PF08592.11 KXS21580.1 - 0.52 10.6 4.5 0.56 10.5 1.7 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) SHMT PF00464.19 KXS21581.1 - 9.6e-197 653.4 0.0 1.1e-196 653.2 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Pkinase_Tyr PF07714.17 KXS21582.1 - 9.7e-24 84.0 0.0 1.4e-23 83.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXS21582.1 - 2.1e-20 73.2 0.0 3e-20 72.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KXS21582.1 - 0.00033 20.1 0.0 0.00045 19.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KXS21582.1 - 0.016 14.5 0.0 0.022 14.1 0.0 1.1 1 0 0 1 1 1 0 Kinase-like Haspin_kinase PF12330.8 KXS21582.1 - 0.026 13.5 0.0 0.037 13.0 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pox_ser-thr_kin PF05445.11 KXS21582.1 - 0.038 13.0 0.0 0.039 12.9 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase zf-PARP PF00645.18 KXS21583.1 - 2.8e-31 108.2 3.5 6.8e-15 55.7 0.2 2.5 2 0 0 2 2 2 2 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region ASXH PF13919.6 KXS21583.1 - 0.012 15.6 0.1 0.023 14.7 0.1 1.6 1 1 0 1 1 1 0 Asx homology domain Pox_Ag35 PF03286.14 KXS21583.1 - 5.6 6.7 17.0 0.43 10.3 9.4 2.1 2 0 0 2 2 2 0 Pox virus Ag35 surface protein MTS PF05175.14 KXS21584.1 - 9.3e-08 31.8 0.0 3.2e-07 30.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase small domain NAD_binding_8 PF13450.6 KXS21584.1 - 0.00056 20.1 0.5 0.0012 19.1 0.5 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Methyltransf_31 PF13847.6 KXS21584.1 - 0.0081 16.0 0.0 0.012 15.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KXS21584.1 - 0.032 13.6 0.0 0.05 13.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Copine PF07002.16 KXS21585.1 - 1.4e-55 188.1 0.0 1.9e-55 187.7 0.0 1.2 1 0 0 1 1 1 1 Copine C2 PF00168.30 KXS21585.1 - 5.9e-16 58.6 0.0 3.5e-15 56.2 0.0 2.1 2 0 0 2 2 2 1 C2 domain vWA-TerF-like PF10138.9 KXS21585.1 - 0.0039 17.3 0.0 0.0071 16.5 0.0 1.5 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA PF00092.28 KXS21585.1 - 0.013 15.8 0.0 0.023 15.0 0.0 1.3 1 0 0 1 1 1 0 von Willebrand factor type A domain Glyco_hydro_26 PF02156.15 KXS21586.1 - 2.3e-07 30.6 1.1 0.0014 18.1 0.0 2.3 2 0 0 2 2 2 2 Glycosyl hydrolase family 26 EF-hand_5 PF13202.6 KXS21586.1 - 0.0062 16.0 0.0 0.016 14.7 0.0 1.7 1 0 0 1 1 1 1 EF hand Glyco_hydro_26 PF02156.15 KXS21587.1 - 1.6e-08 34.4 7.6 3.4e-07 30.0 0.2 2.6 3 0 0 3 3 3 2 Glycosyl hydrolase family 26 ZZ PF00569.17 KXS21588.1 - 1.1e-18 66.7 76.0 3.6e-08 33.1 8.3 5.7 6 0 0 6 6 6 4 Zinc finger, ZZ type zf-C3HC4_3 PF13920.6 KXS21588.1 - 8.6e-09 35.1 10.5 8.6e-09 35.1 10.5 6.7 5 3 0 5 5 5 2 Zinc finger, C3HC4 type (RING finger) C1_2 PF03107.16 KXS21588.1 - 1.2e-06 28.7 57.9 0.00027 21.2 1.9 6.0 5 1 1 6 6 6 4 C1 domain Prok-RING_4 PF14447.6 KXS21588.1 - 4.6e-05 23.2 12.3 4.6e-05 23.2 12.3 6.3 5 3 0 5 5 5 1 Prokaryotic RING finger family 4 MSP1_C PF07462.11 KXS21588.1 - 0.11 11.1 0.0 0.14 10.8 0.0 1.0 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus dUTPase PF00692.19 KXS21589.1 - 1.5e-45 154.0 0.0 1.7e-45 153.9 0.0 1.0 1 0 0 1 1 1 1 dUTPase AAA PF00004.29 KXS21590.1 - 5.8e-55 185.3 0.0 1.9e-39 135.1 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_2 PF02933.17 KXS21590.1 - 1.6e-10 40.6 0.4 2.1e-09 37.0 0.1 2.5 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_2 PF07724.14 KXS21590.1 - 1.8e-09 38.0 0.0 8.1e-06 26.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KXS21590.1 - 5e-09 36.8 0.2 0.0048 17.3 0.0 3.1 2 2 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 KXS21590.1 - 7.5e-09 36.0 0.9 0.0081 16.4 0.1 4.1 2 2 0 2 2 2 2 AAA domain AAA_lid_3 PF17862.1 KXS21590.1 - 1.3e-08 34.5 0.2 6.9e-08 32.2 0.1 2.1 2 0 0 2 2 2 1 AAA+ lid domain TIP49 PF06068.13 KXS21590.1 - 2.4e-07 30.3 0.0 0.02 14.1 0.0 2.2 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_5 PF07728.14 KXS21590.1 - 5e-07 29.8 0.0 0.00099 19.1 0.0 3.2 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KXS21590.1 - 7.6e-07 29.0 0.0 0.028 14.2 0.0 2.8 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 KXS21590.1 - 9.7e-07 28.7 0.1 0.0034 17.1 0.0 2.8 2 1 0 2 2 2 2 AAA domain AAA_33 PF13671.6 KXS21590.1 - 7.5e-06 26.2 0.0 0.16 12.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 KXS21590.1 - 8.9e-06 25.2 0.4 0.008 15.6 0.2 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 KXS21590.1 - 9.1e-06 26.0 0.0 0.047 14.1 0.0 2.6 2 0 0 2 2 2 2 RNA helicase AAA_18 PF13238.6 KXS21590.1 - 1.4e-05 25.7 0.0 0.036 14.6 0.0 3.2 2 1 0 3 3 3 1 AAA domain AAA_7 PF12775.7 KXS21590.1 - 1.6e-05 24.5 0.0 0.026 14.0 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region Sigma54_activat PF00158.26 KXS21590.1 - 4.7e-05 23.2 0.1 0.43 10.3 0.0 2.7 3 0 0 3 3 2 2 Sigma-54 interaction domain IstB_IS21 PF01695.17 KXS21590.1 - 6.7e-05 22.7 0.1 0.11 12.2 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein TsaE PF02367.17 KXS21590.1 - 7.3e-05 22.8 0.0 0.11 12.5 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 KXS21590.1 - 0.00065 19.7 1.9 0.97 9.3 0.0 3.6 4 0 0 4 4 4 1 NACHT domain ABC_tran PF00005.27 KXS21590.1 - 0.0007 20.1 0.1 0.78 10.3 0.0 2.6 2 0 0 2 2 2 1 ABC transporter ATPase_2 PF01637.18 KXS21590.1 - 0.00075 19.5 0.2 10 6.0 0.0 4.3 3 2 1 5 5 5 0 ATPase domain predominantly from Archaea Parvo_NS1 PF01057.17 KXS21590.1 - 0.00083 18.5 0.0 0.76 8.8 0.0 2.5 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 ATPase PF06745.13 KXS21590.1 - 0.00086 18.7 0.3 0.0088 15.4 0.1 2.2 2 0 0 2 2 2 1 KaiC PhoH PF02562.16 KXS21590.1 - 0.0014 18.1 0.0 1.9 7.9 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein NB-ARC PF00931.22 KXS21590.1 - 0.0019 17.4 0.0 2 7.5 0.0 2.5 2 0 0 2 2 2 2 NB-ARC domain AAA_30 PF13604.6 KXS21590.1 - 0.0024 17.6 0.0 0.54 9.9 0.0 2.9 3 0 0 3 3 3 1 AAA domain ResIII PF04851.15 KXS21590.1 - 0.0024 17.9 0.0 1.4 8.9 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_14 PF13173.6 KXS21590.1 - 0.0025 17.8 0.0 2.1 8.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KXS21590.1 - 0.0045 16.6 2.3 1.6 8.3 0.0 3.5 2 2 1 4 4 4 1 AAA domain DUF2075 PF09848.9 KXS21590.1 - 0.0051 16.1 0.2 0.62 9.2 0.0 2.8 2 1 1 3 3 3 1 Uncharacterized conserved protein (DUF2075) CDC48_N PF02359.18 KXS21590.1 - 0.0061 16.7 0.0 0.022 14.9 0.0 2.0 1 1 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_11 PF13086.6 KXS21590.1 - 0.013 15.3 0.2 0.63 9.8 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KXS21590.1 - 0.015 15.0 0.0 1.6 8.5 0.0 2.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_28 PF13521.6 KXS21590.1 - 0.021 15.1 0.0 4.2 7.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain Cytidylate_kin PF02224.18 KXS21590.1 - 0.022 14.5 0.1 2.9 7.6 0.0 2.7 3 0 0 3 3 3 0 Cytidylate kinase AAA_19 PF13245.6 KXS21590.1 - 0.024 15.0 0.5 1 9.7 0.0 3.0 3 1 0 3 3 2 0 AAA domain T2SSE PF00437.20 KXS21590.1 - 0.029 13.4 0.0 6.9 5.6 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein TniB PF05621.11 KXS21590.1 - 0.033 13.6 0.0 16 4.9 0.1 3.3 2 1 0 2 2 2 0 Bacterial TniB protein AAA_3 PF07726.11 KXS21590.1 - 0.066 13.1 0.0 0.63 9.9 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Torsin PF06309.11 KXS21590.1 - 0.073 13.2 0.0 2.3 8.3 0.0 2.4 2 0 0 2 2 2 0 Torsin CPT PF07931.12 KXS21590.1 - 0.076 12.8 0.1 1.3 8.8 0.0 2.3 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein DAP3 PF10236.9 KXS21590.1 - 0.12 11.6 0.0 5.1 6.2 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 AAA_23 PF13476.6 KXS21590.1 - 0.12 12.8 0.4 0.75 10.3 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_17 PF13207.6 KXS21590.1 - 0.13 12.6 0.0 27 5.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain EF_TS PF00889.19 KXS21593.1 - 3.1e-11 43.3 0.0 2.9e-10 40.1 0.0 2.4 2 1 0 2 2 2 1 Elongation factor TS RNase_PH PF01138.21 KXS21594.1 - 3.9e-19 69.4 0.1 2.3e-18 67.0 0.1 2.2 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KXS21594.1 - 4e-09 36.4 0.0 8.8e-09 35.3 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 FGAR-AT_linker PF18072.1 KXS21594.1 - 0.083 13.4 0.0 0.16 12.6 0.0 1.4 1 0 0 1 1 1 0 Formylglycinamide ribonucleotide amidotransferase linker domain Ank_2 PF12796.7 KXS21595.1 - 6.6e-25 87.5 0.0 4.1e-07 30.5 0.0 3.3 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXS21595.1 - 2.3e-15 56.7 0.0 0.0038 17.8 0.0 5.7 2 1 5 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXS21595.1 - 1.2e-13 49.9 0.9 0.32 11.7 0.0 7.6 8 0 0 8 8 8 4 Ankyrin repeat Ank_5 PF13857.6 KXS21595.1 - 1.4e-09 38.0 6.0 1.7 9.1 0.0 6.5 3 3 4 7 7 7 4 Ankyrin repeats (many copies) Ank PF00023.30 KXS21595.1 - 1.5e-08 34.7 0.9 5.9 7.5 0.0 6.7 5 1 1 6 6 6 1 Ankyrin repeat TRAPP PF04051.16 KXS21596.1 - 1.5e-41 141.5 0.0 1.6e-41 141.4 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component DnaJ PF00226.31 KXS21597.1 - 2.4e-18 66.0 0.2 5.1e-18 64.9 0.0 1.6 2 0 0 2 2 2 1 DnaJ domain zf-CSL PF05207.13 KXS21597.1 - 3.4e-18 65.1 0.4 5.2e-18 64.5 0.4 1.3 1 0 0 1 1 1 1 CSL zinc finger DUF5456 PF17539.2 KXS21597.1 - 0.029 14.2 0.1 0.045 13.6 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5456) zinc_ribbon_4 PF13717.6 KXS21597.1 - 0.065 13.2 0.2 0.1 12.5 0.2 1.3 1 0 0 1 1 1 0 zinc-ribbon domain Fcf1 PF04900.12 KXS21598.1 - 2.3e-36 124.1 1.3 2.3e-36 124.1 1.3 1.6 2 0 0 2 2 2 1 Fcf1 PIN_9 PF18477.1 KXS21598.1 - 4.8e-11 43.0 0.1 1.9e-10 41.1 0.0 1.8 2 0 0 2 2 2 1 PIN like domain DUF116 PF01976.17 KXS21598.1 - 0.013 15.1 1.5 0.024 14.2 1.5 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF116 Cyt-b5 PF00173.28 KXS21599.1 - 9.2e-13 48.1 0.0 1.3e-12 47.6 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Potass_KdpF PF09604.10 KXS21599.1 - 0.0066 16.4 0.5 0.0093 15.9 0.5 1.2 1 0 0 1 1 1 1 F subunit of K+-transporting ATPase (Potass_KdpF) PALP PF00291.25 KXS21600.1 - 1e-26 94.0 0.4 1.3e-25 90.5 0.4 2.0 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.28 KXS21600.1 - 1.5e-12 47.7 0.1 8e-06 26.2 0.0 4.1 5 0 0 5 5 5 2 CBS domain DUF2383 PF09537.10 KXS21602.1 - 0.092 13.1 0.1 0.31 11.4 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF2383) Bromodomain PF00439.25 KXS21603.1 - 1.3e-61 204.6 9.2 3.9e-20 71.7 0.2 3.4 3 0 0 3 3 3 3 Bromodomain Ank_2 PF12796.7 KXS21603.1 - 3.6e-08 33.9 0.0 7.6e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KXS21603.1 - 1.4e-05 25.3 0.0 0.0061 17.0 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 KXS21603.1 - 1.6e-05 25.1 0.0 0.0073 16.6 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXS21603.1 - 1.6e-05 25.3 0.1 0.0011 19.5 0.0 2.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXS21603.1 - 0.0018 18.6 0.0 1.1 10.0 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeat PuR_N PF09182.10 KXS21603.1 - 0.089 12.7 0.0 6.7 6.7 0.0 2.6 2 0 0 2 2 2 0 Bacterial purine repressor, N-terminal DUF4777 PF16007.5 KXS21603.1 - 0.14 12.5 0.1 47 4.3 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4777) Sin_N PF04801.13 KXS21604.1 - 8.3e-57 193.3 0.0 6.7e-53 180.4 0.0 2.7 2 1 0 2 2 2 2 Sin-like protein conserved region DUF4483 PF14825.6 KXS21605.1 - 0.00049 19.9 0.7 0.13 12.0 0.0 3.3 3 1 0 3 3 3 2 Domain of unknown function (DUF4483) WD40_4 PF16300.5 KXS21606.1 - 3.5e-30 103.6 0.0 6.8e-15 54.7 0.0 2.6 2 0 0 2 2 2 2 Type of WD40 repeat WD40 PF00400.32 KXS21606.1 - 5.7e-17 61.8 15.4 0.0067 17.3 0.0 9.3 10 0 0 10 10 10 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXS21606.1 - 7.2e-11 42.3 0.0 0.0084 16.4 0.0 5.2 4 2 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain DUF1899 PF08953.11 KXS21606.1 - 7.7e-10 38.5 0.0 1.4e-05 24.9 0.0 3.0 2 0 0 2 2 2 2 Domain of unknown function (DUF1899) Nbas_N PF15492.6 KXS21606.1 - 0.017 14.5 0.1 1.6 8.0 0.0 2.9 2 1 2 4 4 4 0 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.12 KXS21606.1 - 0.069 13.1 0.0 0.21 11.6 0.0 1.9 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat ATG101 PF07855.12 KXS21607.1 - 1.8e-39 135.2 0.0 2.1e-39 135.0 0.0 1.0 1 0 0 1 1 1 1 Autophagy-related protein 101 ATP_bind_1 PF03029.17 KXS21608.1 - 4.4e-88 295.1 0.0 5e-88 294.9 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein CLP1_P PF16575.5 KXS21608.1 - 1.6e-05 24.7 0.0 0.00024 21.0 0.0 2.3 2 1 1 3 3 3 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_16 PF13191.6 KXS21608.1 - 0.0001 22.7 0.0 0.00089 19.7 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 KXS21608.1 - 0.00031 21.3 0.1 0.0013 19.2 0.1 2.2 1 1 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.18 KXS21608.1 - 0.001 18.5 0.0 0.0023 17.3 0.0 1.6 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_22 PF13401.6 KXS21608.1 - 0.0011 19.2 0.4 0.0026 18.1 0.0 1.8 2 0 0 2 2 1 1 AAA domain CbiA PF01656.23 KXS21608.1 - 0.0014 18.7 0.0 0.0017 18.4 0.0 1.3 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_30 PF13604.6 KXS21608.1 - 0.0015 18.3 0.0 0.0024 17.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KXS21608.1 - 0.0021 17.8 0.0 0.0044 16.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain cobW PF02492.19 KXS21608.1 - 0.0023 17.5 0.1 0.017 14.7 0.1 2.0 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 KXS21608.1 - 0.0024 17.4 0.0 0.0053 16.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region GTP_EFTU PF00009.27 KXS21608.1 - 0.0032 17.1 0.0 0.11 12.0 0.0 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 KXS21608.1 - 0.009 16.5 0.0 0.016 15.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SRP54 PF00448.22 KXS21608.1 - 0.0093 15.6 0.1 0.022 14.4 0.0 1.6 2 0 0 2 2 1 1 SRP54-type protein, GTPase domain Gtr1_RagA PF04670.12 KXS21608.1 - 0.01 15.2 0.3 1.6 8.0 0.1 2.2 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region MeaB PF03308.16 KXS21608.1 - 0.013 14.5 0.0 0.025 13.6 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_33 PF13671.6 KXS21608.1 - 0.017 15.3 0.0 0.031 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_31 PF13614.6 KXS21608.1 - 0.018 14.9 0.2 5.6 6.8 0.3 2.5 2 1 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 KXS21608.1 - 0.021 14.2 0.4 0.038 13.4 0.4 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Viral_helicase1 PF01443.18 KXS21608.1 - 0.023 14.5 0.0 0.035 13.9 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase MMR_HSR1 PF01926.23 KXS21608.1 - 0.032 14.3 0.0 0.082 13.0 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_10 PF12846.7 KXS21608.1 - 0.036 13.0 0.0 0.054 12.4 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain RNA_helicase PF00910.22 KXS21608.1 - 0.037 14.4 0.0 0.078 13.4 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA PF00004.29 KXS21608.1 - 0.04 14.3 0.1 0.15 12.5 0.0 2.0 3 0 0 3 3 1 0 ATPase family associated with various cellular activities (AAA) Cytidylate_kin PF02224.18 KXS21608.1 - 0.052 13.3 0.1 0.085 12.6 0.1 1.3 1 0 0 1 1 1 0 Cytidylate kinase Sigma54_activ_2 PF14532.6 KXS21608.1 - 0.054 13.6 0.0 0.61 10.2 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_14 PF13173.6 KXS21608.1 - 0.074 13.1 0.0 0.13 12.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain KTI12 PF08433.10 KXS21608.1 - 0.077 12.4 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_19 PF13245.6 KXS21608.1 - 0.082 13.2 0.1 0.18 12.1 0.1 1.6 2 0 0 2 2 1 0 AAA domain RsgA_GTPase PF03193.16 KXS21608.1 - 0.087 12.7 0.1 1.5 8.7 0.0 2.6 2 1 1 3 3 3 0 RsgA GTPase DUF815 PF05673.13 KXS21608.1 - 0.09 11.9 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Thymidylate_kin PF02223.17 KXS21608.1 - 0.097 12.3 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Thymidylate kinase ArsA_ATPase PF02374.15 KXS21608.1 - 0.098 11.8 0.0 0.25 10.5 0.0 1.6 2 0 0 2 2 2 0 Anion-transporting ATPase NTPase_1 PF03266.15 KXS21608.1 - 0.11 12.4 0.1 0.55 10.1 0.0 2.0 2 0 0 2 2 2 0 NTPase T2SSE PF00437.20 KXS21608.1 - 0.13 11.3 0.0 0.24 10.4 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_25 PF13481.6 KXS21608.1 - 0.13 11.8 0.5 1.4 8.4 0.1 2.4 3 0 0 3 3 3 0 AAA domain TrwB_AAD_bind PF10412.9 KXS21608.1 - 0.14 11.0 0.0 0.2 10.5 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_29 PF13555.6 KXS21608.1 - 0.16 11.8 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATPase PF06745.13 KXS21608.1 - 0.19 11.0 0.0 0.59 9.4 0.0 1.8 2 0 0 2 2 2 0 KaiC PduV-EutP PF10662.9 KXS21608.1 - 0.22 11.3 0.4 1.1 9.0 0.1 2.1 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation IBN_N PF03810.19 KXS21609.1 - 2.4e-15 56.2 0.2 9.6e-15 54.3 0.0 2.2 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.12 KXS21609.1 - 1.2e-05 25.4 0.0 0.00049 20.2 0.0 3.3 3 0 0 3 3 3 1 Exportin 1-like protein HEAT PF02985.22 KXS21609.1 - 0.00034 20.6 0.3 3.1 8.3 0.0 5.2 5 0 0 5 5 5 1 HEAT repeat HEAT_EZ PF13513.6 KXS21609.1 - 0.0068 16.9 4.2 30 5.3 0.0 5.8 6 1 1 7 7 7 1 HEAT-like repeat HEAT_2 PF13646.6 KXS21609.1 - 0.069 13.5 7.4 0.7 10.3 0.0 5.0 7 1 0 7 7 7 0 HEAT repeats Adaptin_N PF01602.20 KXS21609.1 - 0.2 10.1 0.0 2.8 6.4 0.0 2.5 2 1 0 2 2 2 0 Adaptin N terminal region Sel1 PF08238.12 KXS21610.1 - 6.3e-38 128.4 30.3 1.4e-08 35.1 0.0 8.1 8 0 0 8 8 8 6 Sel1 repeat ANAPC3 PF12895.7 KXS21610.1 - 0.33 11.2 2.6 6.1 7.2 0.7 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 KXS21610.1 - 0.66 10.9 10.3 12 7.0 0.2 4.6 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 KXS21610.1 - 0.9 10.1 4.2 7.6 7.2 0.3 3.8 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 KXS21610.1 - 1.8 8.9 7.3 0.93 9.8 0.2 3.8 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 KXS21610.1 - 5.2 7.0 10.5 2.4 8.1 0.2 4.9 6 0 0 6 6 6 0 Tetratricopeptide repeat zf-primase PF09329.11 KXS21611.1 - 2.2e-15 56.2 2.2 3.4e-15 55.6 2.2 1.3 1 0 0 1 1 1 1 Primase zinc finger PIN_4 PF13638.6 KXS21611.1 - 0.058 13.7 0.1 0.18 12.1 0.0 1.7 2 0 0 2 2 2 0 PIN domain HMA PF00403.26 KXS21612.1 - 2.9e-15 56.4 0.4 3.3e-15 56.3 0.4 1.0 1 0 0 1 1 1 1 Heavy-metal-associated domain Fer2_BFD PF04324.15 KXS21612.1 - 0.016 15.5 0.1 0.045 14.1 0.0 1.7 2 0 0 2 2 2 0 BFD-like [2Fe-2S] binding domain UBX PF00789.20 KXS21613.1 - 4.9e-18 65.1 0.1 1.5e-17 63.5 0.0 1.9 2 0 0 2 2 2 1 UBX domain UBA PF00627.31 KXS21613.1 - 5e-05 23.1 0.0 0.0001 22.1 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain TAF4 PF05236.14 KXS21613.1 - 0.057 13.2 19.6 0.074 12.8 19.6 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family zf-C2H2_2 PF12756.7 KXS21613.1 - 0.087 13.2 1.3 0.29 11.5 0.1 2.2 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Borrelia_P83 PF05262.11 KXS21613.1 - 0.22 10.0 21.4 0.24 9.8 21.4 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF3138 PF11336.8 KXS21613.1 - 2.1 6.9 7.6 3.3 6.2 7.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) SOBP PF15279.6 KXS21613.1 - 2.2 8.8 6.5 2.8 8.5 6.5 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein HMG_CoA_synt_C PF08540.10 KXS21614.1 - 9.4e-106 353.5 0.2 1.2e-105 353.2 0.2 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 KXS21614.1 - 1.2e-92 308.5 0.2 2e-92 307.8 0.2 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal ACP_syn_III_C PF08541.10 KXS21614.1 - 0.088 13.0 0.0 20 5.4 0.0 2.4 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal p450 PF00067.22 KXS21615.1 - 1.5e-75 254.7 0.0 1.7e-75 254.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PRKG1_interact PF15898.5 KXS21616.1 - 0.06 14.3 4.6 0.15 13.0 4.6 1.7 1 1 0 1 1 1 0 cGMP-dependent protein kinase interacting domain Cob_adeno_trans PF01923.18 KXS21616.1 - 0.28 11.3 2.1 0.49 10.5 1.5 1.6 1 1 0 1 1 1 0 Cobalamin adenosyltransferase DUF16 PF01519.16 KXS21616.1 - 2.2 8.8 5.8 10 6.7 1.3 2.2 1 1 1 2 2 2 0 Protein of unknown function DUF16 DHHC PF01529.20 KXS21617.1 - 1.2e-26 93.4 10.4 1.2e-26 93.4 10.4 2.2 2 0 0 2 2 2 2 DHHC palmitoyltransferase Trm112p PF03966.16 KXS21618.1 - 1.4e-16 60.8 0.0 1.8e-16 60.5 0.0 1.1 1 0 0 1 1 1 1 Trm112p-like protein zf-Nse PF11789.8 KXS21618.1 - 0.04 13.7 0.3 1.2 9.0 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-C2HC PF01530.18 KXS21618.1 - 2.3 8.5 5.2 12 6.2 0.6 2.3 2 0 0 2 2 2 0 Zinc finger, C2HC type Exo_endo_phos PF03372.23 KXS21619.1 - 1.2e-19 70.8 0.0 3.1e-19 69.4 0.0 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.7 KXS21619.1 - 5.5e-10 39.3 4.9 2.9e-05 24.3 0.8 3.0 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXS21619.1 - 1.1e-07 31.5 4.0 2.7e-06 27.0 1.4 2.5 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.33 KXS21619.1 - 0.025 15.1 1.5 24 6.0 0.2 4.0 2 1 1 3 3 3 0 Leucine Rich Repeat zf-H2C2_2 PF13465.6 KXS21620.1 - 1.9e-09 37.5 4.4 2.5e-06 27.7 0.0 3.6 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 KXS21620.1 - 0.0021 18.4 16.3 0.024 15.1 1.0 3.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KXS21620.1 - 1.1 9.7 5.7 8.5 6.8 0.3 3.2 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-HIT PF04438.16 KXS21620.1 - 1.1 9.2 2.9 24 4.9 0.4 2.3 2 0 0 2 2 2 0 HIT zinc finger zf-C2H2_4 PF13894.6 KXS21620.1 - 3.8 8.6 16.7 1.9 9.6 0.6 3.8 4 0 0 4 4 4 0 C2H2-type zinc finger eRF1_2 PF03464.15 KXS21621.1 - 8.6e-46 155.6 0.2 1.4e-45 154.8 0.2 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 KXS21621.1 - 1e-37 129.1 0.2 2.4e-37 127.9 0.2 1.7 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 KXS21621.1 - 8.2e-21 74.4 0.0 2e-20 73.1 0.0 1.7 1 0 0 1 1 1 1 eRF1 domain 1 acVLRF1 PF18859.1 KXS21621.1 - 1e-08 35.5 0.0 1.5e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor baeRF_family10 PF18854.1 KXS21621.1 - 1.3e-08 35.1 0.0 2e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 6PGD PF00393.19 KXS21622.1 - 1.5e-125 418.4 0.0 1.9e-125 418.1 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 KXS21622.1 - 2.5e-51 174.0 0.0 4.4e-51 173.2 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KXS21622.1 - 0.002 18.7 0.2 0.0053 17.3 0.1 1.8 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 KXS21622.1 - 0.12 11.7 0.0 0.26 10.6 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RRM_1 PF00076.22 KXS21623.1 - 9.7e-18 63.8 0.2 4.4e-09 36.0 0.0 3.1 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KXS21623.1 - 0.011 15.8 0.0 0.025 14.7 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif RNA_pol_Rbc25 PF08292.12 KXS21623.1 - 3.3 8.0 5.2 9.7 6.4 0.0 2.8 3 0 0 3 3 3 0 RNA polymerase III subunit Rpc25 LSM14 PF12701.7 KXS21624.1 - 1.6e-22 79.4 0.0 2.4e-22 78.8 0.0 1.3 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.10 KXS21624.1 - 6.6e-09 36.6 3.3 6.6e-09 36.6 3.3 2.1 2 1 0 2 2 2 1 FDF domain SM-ATX PF14438.6 KXS21624.1 - 1.4e-05 25.1 0.0 2.2e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain XPC-binding PF09280.11 KXS21624.1 - 0.043 13.6 6.5 0.078 12.7 6.5 1.3 1 0 0 1 1 1 0 XPC-binding domain Zn_clus PF00172.18 KXS21625.1 - 2.6e-06 27.4 7.0 4.1e-06 26.8 7.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Evr1_Alr PF04777.13 KXS21627.1 - 1.9e-29 102.1 0.0 2.2e-29 101.9 0.0 1.0 1 0 0 1 1 1 1 Erv1 / Alr family SNAD4 PF18750.1 KXS21627.1 - 0.066 13.3 0.0 0.088 12.9 0.0 1.3 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 DSPc PF00782.20 KXS21628.1 - 2.2e-17 63.1 0.0 1.7e-14 53.8 0.0 2.3 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KXS21628.1 - 0.018 14.6 0.0 0.031 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DHO_dh PF01180.21 KXS21629.1 - 2.2e-93 312.7 0.0 2.7e-93 312.4 0.0 1.1 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.18 KXS21629.1 - 0.0011 18.1 0.1 0.0045 16.1 0.1 1.9 2 0 0 2 2 2 1 FMN-dependent dehydrogenase ScsC_N PF18312.1 KXS21629.1 - 0.12 12.2 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 Copper resistance protein ScsC N-terminal domain Dus PF01207.17 KXS21629.1 - 0.17 10.9 0.0 0.85 8.7 0.0 1.9 1 1 0 1 1 1 0 Dihydrouridine synthase (Dus) UFD1 PF03152.14 KXS21630.1 - 1.1e-72 243.1 0.0 1.4e-72 242.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 KH_1 PF00013.29 KXS21631.1 - 5.7e-56 186.2 8.9 6.2e-19 67.6 0.6 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 KXS21631.1 - 7.8e-13 48.1 2.0 0.0015 18.3 0.2 3.4 3 0 0 3 3 3 3 KH domain MOEP19 PF16005.5 KXS21631.1 - 4.9e-07 29.6 0.0 0.42 10.6 0.0 3.2 3 0 0 3 3 3 3 KH-like RNA-binding domain KH_5 PF13184.6 KXS21631.1 - 9.2e-07 28.9 0.7 0.86 9.7 0.1 3.5 3 0 0 3 3 3 3 NusA-like KH domain KH_4 PF13083.6 KXS21631.1 - 1.9e-06 27.6 1.8 0.25 11.2 0.1 3.5 3 0 0 3 3 3 3 KH domain SLS PF14611.6 KXS21631.1 - 9.7e-06 25.6 0.0 0.088 12.6 0.0 3.1 3 0 0 3 3 3 2 Mitochondrial inner-membrane-bound regulator Secretin_N PF03958.17 KXS21631.1 - 0.0069 16.8 0.6 4.1 7.9 0.0 3.6 3 0 0 3 3 3 1 Bacterial type II/III secretion system short domain DUF2067 PF09840.9 KXS21631.1 - 0.11 12.0 0.1 1.6 8.2 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2067) Mak10 PF04112.13 KXS21632.1 - 5.2e-17 61.9 0.0 4.6e-14 52.3 0.0 2.5 1 1 1 2 2 2 2 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Ndc1_Nup PF09531.10 KXS21633.1 - 4.4e-61 207.3 0.0 7e-61 206.7 0.0 1.2 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup TAFII28 PF04719.14 KXS21635.1 - 1.6e-28 98.6 0.0 3.1e-28 97.7 0.0 1.5 1 0 0 1 1 1 1 hTAFII28-like protein conserved region Inv-AAD PF18785.1 KXS21636.1 - 4.5e-25 88.0 0.1 4.8e-24 84.7 0.1 2.0 1 1 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase dCMP_cyt_deam_1 PF00383.23 KXS21636.1 - 1.7e-19 69.6 0.1 2e-19 69.3 0.1 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KXS21636.1 - 1.6e-05 24.7 0.0 2e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 MafB19-like deaminase APOBEC_N PF08210.11 KXS21636.1 - 0.0029 17.5 0.0 0.0069 16.3 0.0 1.6 1 1 1 2 2 2 1 APOBEC-like N-terminal domain UbiA PF01040.18 KXS21637.1 - 6.4e-47 160.0 22.7 8.5e-47 159.6 22.7 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family CIAPIN1 PF05093.13 KXS21638.1 - 4.2e-25 88.2 13.5 2.4e-22 79.3 13.5 2.7 1 1 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Methyltransf_25 PF13649.6 KXS21638.1 - 0.077 13.7 0.0 0.14 12.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain WD40 PF00400.32 KXS21639.1 - 8.4e-25 86.6 22.4 5.6e-05 23.8 0.1 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXS21639.1 - 8.8e-06 25.9 1.7 6 7.2 0.1 5.4 3 3 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Big_2 PF02368.18 KXS21639.1 - 0.14 12.0 0.3 0.54 10.2 0.3 2.0 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 2) HECT PF00632.25 KXS21640.1 - 7.1e-98 327.9 0.0 9.3e-98 327.5 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 KXS21640.1 - 4.3e-36 122.7 13.9 1.8e-11 43.9 4.4 3.7 3 0 0 3 3 3 3 WW domain C2 PF00168.30 KXS21640.1 - 1.9e-18 66.6 0.4 5e-18 65.3 0.4 1.7 1 0 0 1 1 1 1 C2 domain Ribosomal_L3 PF00297.22 KXS21641.1 - 2e-22 79.7 7.9 5.2e-19 68.5 5.0 3.3 1 1 3 4 4 4 3 Ribosomal protein L3 DnaJ PF00226.31 KXS21642.1 - 5e-19 68.2 0.0 9e-19 67.4 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain HTH_9 PF08221.11 KXS21643.1 - 7.4e-21 74.0 0.4 6.3e-18 64.6 0.0 3.2 3 0 0 3 3 3 2 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.17 KXS21643.1 - 8.1e-11 41.7 0.2 0.00062 19.6 0.0 2.7 3 0 0 3 3 3 2 TFIIE alpha subunit RNA_pol_Rpc82 PF05645.13 KXS21643.1 - 0.013 15.2 0.0 0.043 13.6 0.0 1.9 1 1 0 1 1 1 0 RNA polymerase III subunit RPC82 DOCK-C2 PF14429.6 KXS21644.1 - 1.2e-36 126.4 0.0 3e-36 125.1 0.0 1.7 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins DUF3398 PF11878.8 KXS21644.1 - 3.6e-08 33.8 0.1 8.4e-08 32.6 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3398) Hyccin PF09790.9 KXS21644.1 - 0.14 11.3 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Hyccin DHR-2 PF06920.13 KXS21645.1 - 2.8e-157 524.6 0.2 3.3e-157 524.3 0.2 1.0 1 0 0 1 1 1 1 Dock homology region 2 Rab15_effector PF15208.6 KXS21645.1 - 0.05 12.9 0.1 0.17 11.1 0.0 1.8 2 0 0 2 2 2 0 Rab15 effector Sarcoglycan_1 PF04790.13 KXS21646.1 - 0.064 12.6 0.0 0.068 12.5 0.0 1.1 1 0 0 1 1 1 0 Sarcoglycan complex subunit protein TPX2_importin PF12214.8 KXS21647.1 - 3e-15 56.8 45.0 3.6e-08 33.8 12.9 6.9 3 2 3 6 6 6 5 Cell cycle regulated microtubule associated protein TPX2 PF06886.11 KXS21647.1 - 1.4e-09 38.0 13.5 1.4e-09 38.0 13.5 4.0 4 0 0 4 4 4 1 Targeting protein for Xklp2 (TPX2) Aurora-A_bind PF09041.10 KXS21647.1 - 0.027 14.5 0.1 0.093 12.8 0.1 1.9 1 0 0 1 1 1 0 Aurora-A binding Syja_N PF02383.18 KXS21649.1 - 1.9e-85 287.0 0.0 2.8e-85 286.4 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain Mannosyl_trans PF05007.13 KXS21651.1 - 1.3e-69 235.0 20.0 1.8e-69 234.5 20.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.13 KXS21651.1 - 3.4e-12 46.1 18.8 4.9e-12 45.6 18.8 1.1 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U GT87 PF09594.10 KXS21651.1 - 1.5e-05 24.9 15.6 1.5e-05 24.9 15.6 2.3 1 1 0 1 1 1 1 Glycosyltransferase family 87 RasGAP PF00616.19 KXS21652.1 - 1.5e-07 31.4 0.0 0.0034 17.1 0.0 2.2 2 0 0 2 2 2 2 GTPase-activator protein for Ras-like GTPase CTP_transf_like PF01467.26 KXS21654.1 - 1.1e-22 80.8 0.0 1.4e-22 80.5 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase-like zinc_ribbon_6 PF14599.6 KXS21655.1 - 8.2e-27 93.0 2.6 8.2e-27 93.0 2.6 4.4 4 1 1 5 5 5 1 Zinc-ribbon zf-CHY PF05495.12 KXS21655.1 - 3.9e-18 65.7 22.9 3.9e-18 65.7 22.9 3.8 2 1 1 3 3 3 1 CHY zinc finger zf-RING_2 PF13639.6 KXS21655.1 - 3e-08 33.8 10.6 3e-08 33.8 10.6 5.0 3 1 3 6 6 6 1 Ring finger domain zf-C3HC4_2 PF13923.6 KXS21655.1 - 0.00049 19.9 13.1 0.00049 19.9 13.1 5.3 5 2 1 6 6 6 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KXS21655.1 - 0.0034 17.1 6.4 0.0034 17.1 6.4 4.5 6 0 0 6 6 6 1 RING-like zinc finger DUF2024 PF09630.10 KXS21655.1 - 0.17 11.8 6.7 0.51 10.2 5.6 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF2024) Merozoite_SPAM PF07133.11 KXS21655.1 - 0.54 10.2 14.7 0.89 9.5 14.7 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Chorismate_synt PF01264.21 KXS21656.1 - 1.3e-136 454.6 0.0 1.5e-136 454.4 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase Glyoxalase_3 PF13468.6 KXS21657.1 - 1e-25 90.9 0.0 1.6e-25 90.2 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.6 KXS21657.1 - 2e-07 31.3 0.0 0.00069 19.9 0.0 2.7 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Mito_carr PF00153.27 KXS21658.1 - 2.8e-55 184.2 2.1 1.1e-19 70.2 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DMA PF03474.14 KXS21658.1 - 0.07 12.7 0.0 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 DMRTA motif HAMP_N3 PF18575.1 KXS21659.1 - 0.19 11.4 0.0 0.32 10.6 0.0 1.4 1 0 0 1 1 1 0 HAMP N-terminal domain 3 RAP1 PF07218.11 KXS21659.1 - 5.2 5.2 6.8 7.2 4.8 6.8 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Cpn60_TCP1 PF00118.24 KXS21660.1 - 4.4e-157 523.6 13.0 5e-157 523.5 13.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family TPT PF03151.16 KXS21661.1 - 1.3e-22 80.5 19.6 1.6e-22 80.2 19.6 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KXS21661.1 - 0.064 13.4 33.4 0.089 13.0 14.7 2.7 2 1 0 2 2 2 0 EamA-like transporter family TMEM72 PF16054.5 KXS21661.1 - 0.31 10.7 9.6 0.43 10.2 0.2 2.7 2 1 0 2 2 2 0 Transmembrane protein family 72 FAD_binding_3 PF01494.19 KXS21663.1 - 3e-05 23.4 0.0 3.1e-05 23.4 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KXS21663.1 - 0.0014 17.9 0.0 0.0017 17.7 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXS21663.1 - 0.0016 17.8 0.0 0.0019 17.5 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KXS21663.1 - 0.011 15.0 0.0 0.012 15.0 0.0 1.1 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase HI0933_like PF03486.14 KXS21663.1 - 0.057 12.1 0.0 0.072 11.8 0.0 1.1 1 0 0 1 1 1 0 HI0933-like protein Trp_halogenase PF04820.14 KXS21663.1 - 0.084 11.7 0.0 0.094 11.5 0.0 1.0 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox PF00070.27 KXS21663.1 - 0.12 13.0 0.0 0.21 12.2 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KXS21664.1 - 0.13 11.5 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Nucleotid_trans PF03407.16 KXS21665.1 - 0.025 14.6 0.0 0.044 13.7 0.0 1.3 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase RRM_1 PF00076.22 KXS21668.1 - 2.7e-27 94.4 2.0 2.1e-08 33.9 0.3 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KXS21668.1 - 4.6e-10 39.2 0.3 0.01 15.7 0.0 4.2 4 0 0 4 4 4 3 Occluded RNA-recognition motif DUF4523 PF15023.6 KXS21668.1 - 1.9e-06 27.8 0.0 0.048 13.5 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF4523) RRM_7 PF16367.5 KXS21668.1 - 2.3e-05 24.4 0.1 3.7 7.7 0.0 4.3 4 1 0 4 4 4 2 RNA recognition motif Nup35_RRM_2 PF14605.6 KXS21668.1 - 0.00011 22.1 0.0 0.28 11.2 0.1 3.8 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif RRM_Rrp7 PF17799.1 KXS21668.1 - 0.039 13.7 0.0 1.4 8.7 0.1 2.7 2 1 1 3 3 3 0 Rrp7 RRM-like N-terminal domain ADH_zinc_N PF00107.26 KXS21669.1 - 3.1e-30 104.8 0.2 5.6e-30 104.0 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXS21669.1 - 2e-21 77.4 0.0 4.3e-21 76.4 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXS21669.1 - 2.9e-09 36.8 0.0 1.3e-08 34.7 0.0 1.9 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 KXS21669.1 - 0.084 12.8 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase Aa_trans PF01490.18 KXS21670.1 - 4.1e-36 124.6 0.1 5.5e-36 124.1 0.1 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein TPR_1 PF00515.28 KXS21671.1 - 4.4e-08 32.6 3.0 0.00022 20.9 0.1 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KXS21671.1 - 8.1e-08 31.8 3.7 0.00042 20.2 0.4 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KXS21671.1 - 0.00021 21.5 0.1 0.15 12.4 0.0 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 KXS21671.1 - 0.00066 19.5 0.4 0.26 11.2 0.7 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 KXS21671.1 - 0.00067 19.5 1.3 2 8.6 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 KXS21671.1 - 0.0031 17.1 0.9 0.41 10.4 0.1 3.6 4 0 0 4 4 4 1 TPR repeat FKBP_C PF00254.28 KXS21671.1 - 0.065 13.6 0.0 0.15 12.4 0.0 1.8 1 1 0 1 1 1 0 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_6 PF13174.6 KXS21671.1 - 0.1 13.3 0.2 2.4 9.0 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Pkinase PF00069.25 KXS21672.1 - 2e-59 201.1 0.0 3.1e-59 200.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS21672.1 - 3.1e-42 144.7 0.0 4.9e-42 144.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase OSR1_C PF12202.8 KXS21672.1 - 7.6e-10 38.9 0.6 1.6e-09 37.8 0.6 1.5 1 0 0 1 1 1 1 Oxidative-stress-responsive kinase 1 C-terminal domain Pkinase_fungal PF17667.1 KXS21672.1 - 0.0055 15.5 0.0 0.011 14.6 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KXS21672.1 - 0.1 12.5 0.0 0.39 10.6 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family Cofilin_ADF PF00241.20 KXS21673.1 - 1e-35 122.2 0.0 8.5e-18 64.3 0.0 2.1 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein EF-hand_1 PF00036.32 KXS21675.1 - 5.6e-18 63.1 4.4 1.4e-06 27.4 0.5 3.3 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 KXS21675.1 - 3.6e-15 54.5 3.7 0.00024 20.8 0.4 3.3 3 0 0 3 3 3 3 EF-hand domain EF-hand_7 PF13499.6 KXS21675.1 - 4.9e-14 52.5 1.7 1.2e-07 32.0 0.4 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KXS21675.1 - 1.3e-09 37.1 3.9 0.00065 19.1 0.5 3.4 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 KXS21675.1 - 2.1e-09 37.1 0.9 0.1 12.5 0.0 3.2 3 0 0 3 3 3 3 EF-hand domain pair Dockerin_1 PF00404.18 KXS21675.1 - 0.0053 16.9 0.0 0.03 14.5 0.0 2.1 1 1 1 2 2 2 2 Dockerin type I domain WD40 PF00400.32 KXS21676.1 - 4.2e-57 188.8 20.0 1e-09 38.8 0.1 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXS21676.1 - 3.2e-16 59.4 0.0 0.0046 17.2 0.0 6.3 1 1 5 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KXS21676.1 - 1.3e-06 27.7 1.5 1.9 7.4 0.0 5.3 2 1 4 6 6 6 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KXS21676.1 - 2.8e-06 27.3 0.2 2 8.2 0.0 3.3 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 KXS21676.1 - 0.014 13.9 0.0 0.035 12.7 0.0 1.5 1 1 1 2 2 2 0 Cytochrome D1 heme domain Frtz PF11768.8 KXS21676.1 - 0.033 12.5 0.0 0.27 9.5 0.0 2.1 2 1 0 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz FLgD_tudor PF13861.6 KXS21676.1 - 0.065 13.5 0.1 8.8 6.7 0.0 2.7 3 0 0 3 3 3 0 FlgD Tudor-like domain GYF_2 PF14237.6 KXS21676.1 - 0.18 11.7 0.1 0.91 9.4 0.0 2.3 2 0 0 2 2 2 0 GYF domain 2 CoA_transf_3 PF02515.17 KXS21677.1 - 4.1e-104 348.6 0.0 5.3e-104 348.2 0.0 1.1 1 0 0 1 1 1 1 CoA-transferase family III zf-CCCH PF00642.24 KXS21678.1 - 2.2e-05 24.2 16.3 0.0011 18.8 1.0 3.2 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KXS21678.1 - 0.0046 16.7 10.6 0.16 11.8 0.1 3.5 3 1 0 3 3 3 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KXS21678.1 - 0.0051 16.8 3.1 0.0051 16.8 3.1 3.4 3 1 0 3 3 3 2 Zinc finger domain Torus PF16131.5 KXS21678.1 - 0.031 14.9 8.8 0.095 13.4 0.2 3.0 2 1 1 3 3 3 0 Torus domain ABM PF03992.16 KXS21679.1 - 4.1e-13 49.3 0.0 5.4e-13 48.9 0.0 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase NMO PF03060.15 KXS21680.1 - 2.5e-61 207.9 0.6 3.7e-61 207.4 0.6 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KXS21680.1 - 8.4e-13 48.0 1.1 2.3e-11 43.3 0.4 2.6 2 1 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KXS21680.1 - 3.2e-06 26.4 2.2 3.2e-06 26.4 2.2 1.5 2 0 0 2 2 2 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 KXS21680.1 - 0.0043 16.2 1.1 0.0057 15.8 0.4 1.7 2 0 0 2 2 2 1 Conserved region in glutamate synthase Radial_spoke_3 PF06098.11 KXS21680.1 - 0.23 10.7 0.1 0.31 10.3 0.1 1.1 1 0 0 1 1 1 0 Radial spoke protein 3 Redoxin PF08534.10 KXS21681.1 - 5.6e-35 120.2 0.0 6e-35 120.1 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 KXS21681.1 - 8.1e-12 45.1 0.0 1e-11 44.8 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family DNA_pol_B_thumb PF14791.6 KXS21682.1 - 1.4e-17 63.6 0.0 2.7e-17 62.7 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.9 KXS21682.1 - 1e-13 50.8 0.1 2.4e-13 49.7 0.1 1.7 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda DNA_pol_B_palm PF14792.6 KXS21682.1 - 3.3e-13 49.8 0.0 5.9e-13 49.0 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase beta palm NTP_transf_2 PF01909.23 KXS21682.1 - 0.001 19.3 0.0 0.0021 18.3 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain RNR_N PF08343.10 KXS21682.1 - 0.035 14.1 0.1 0.064 13.3 0.1 1.4 1 0 0 1 1 1 0 Ribonucleotide reductase N-terminal Gb3_synth PF04572.12 KXS21682.1 - 0.15 12.3 0.0 0.59 10.3 0.0 1.9 2 0 0 2 2 2 0 Alpha 1,4-glycosyltransferase conserved region Aldo_ket_red PF00248.21 KXS21683.1 - 3e-30 105.4 0.0 2.1e-26 92.8 0.0 2.0 1 1 0 2 2 2 2 Aldo/keto reductase family PAP_fibrillin PF04755.12 KXS21683.1 - 0.14 12.1 0.0 0.2 11.6 0.0 1.2 1 0 0 1 1 1 0 PAP_fibrillin Closter_coat PF01785.17 KXS21683.1 - 0.15 11.3 0.0 0.26 10.5 0.0 1.3 1 0 0 1 1 1 0 Closterovirus coat protein AA_permease_2 PF13520.6 KXS21684.1 - 2e-62 211.5 46.2 2.3e-62 211.2 46.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXS21684.1 - 3.4e-26 91.9 40.6 4.7e-26 91.4 40.6 1.1 1 0 0 1 1 1 1 Amino acid permease GDA1_CD39 PF01150.17 KXS21685.1 - 7e-69 232.5 0.0 1.8e-32 112.6 0.0 4.1 4 0 0 4 4 4 4 GDA1/CD39 (nucleoside phosphatase) family Pkinase PF00069.25 KXS21686.1 - 1.7e-77 260.4 0.0 2e-77 260.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS21686.1 - 3.9e-34 118.1 0.0 4.6e-34 117.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXS21686.1 - 0.0018 17.1 0.0 0.0034 16.2 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 KXS21686.1 - 0.027 13.8 0.4 6.3 6.0 0.0 2.8 2 1 0 3 3 3 0 Kinase-like Kdo PF06293.14 KXS21686.1 - 0.051 12.9 0.0 0.078 12.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family AAR2 PF05282.11 KXS21688.1 - 4.3e-69 233.6 0.0 5.2e-69 233.3 0.0 1.1 1 0 0 1 1 1 1 AAR2 protein VirB7 PF17413.2 KXS21688.1 - 0.018 14.4 0.0 0.039 13.3 0.0 1.6 1 0 0 1 1 1 0 Outer membrane lipoprotein virB7 SAP130_C PF16014.5 KXS21688.1 - 6.8 5.7 5.9 14 4.7 5.9 1.4 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus Helicase_C PF00271.31 KXS21689.1 - 0.00015 22.1 0.0 0.00025 21.4 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 KXS21689.1 - 0.042 13.0 0.0 0.34 10.1 0.0 1.9 1 1 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 SNF2_N PF00176.23 KXS21689.1 - 0.044 12.5 0.0 0.056 12.2 0.0 1.1 1 0 0 1 1 1 0 SNF2 family N-terminal domain Helicase_C PF00271.31 KXS21690.1 - 7.9e-10 39.1 0.0 9.2e-10 38.9 0.0 1.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain NAC PF01849.18 KXS21691.1 - 4.5e-24 84.2 1.4 5.6e-23 80.7 0.0 2.6 3 0 0 3 3 3 1 NAC domain DnaJ PF00226.31 KXS21692.1 - 2.4e-26 91.6 3.0 3.6e-26 91.1 3.0 1.3 1 0 0 1 1 1 1 DnaJ domain Tmemb_185A PF10269.9 KXS21692.1 - 3e-08 33.7 31.4 0.00044 20.0 18.5 3.5 3 1 0 3 3 3 2 Transmembrane Fragile-X-F protein Apocytochr_F_C PF01333.19 KXS21692.1 - 0.012 15.6 0.0 0.025 14.6 0.0 1.4 1 0 0 1 1 1 0 Apocytochrome F, C-terminal Efg1 PF10153.9 KXS21692.1 - 0.035 14.5 0.1 0.12 12.8 0.0 1.8 2 0 0 2 2 2 0 rRNA-processing protein Efg1 DUF3810 PF12725.7 KXS21692.1 - 2.3 7.5 9.5 1.5 8.1 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3810) Fapy_DNA_glyco PF01149.24 KXS21693.1 - 1.1e-32 113.0 0.1 2.3e-32 112.0 0.1 1.5 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.14 KXS21693.1 - 1.4e-19 69.9 0.0 2.5e-19 69.1 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain FbpA PF05833.11 KXS21693.1 - 0.00087 18.2 0.0 0.0013 17.6 0.0 1.2 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) eIF3_subunit PF08597.10 KXS21693.1 - 0.77 9.6 9.8 4.2 7.2 10.2 1.8 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit FAM92 PF06730.11 KXS21694.1 - 2.4e-19 69.7 4.4 3.2e-19 69.2 4.4 1.2 1 0 0 1 1 1 1 FAM92 protein BAR_3 PF16746.5 KXS21694.1 - 0.00023 21.0 3.9 0.00034 20.4 3.9 1.2 1 0 0 1 1 1 1 BAR domain of APPL family WH2 PF02205.20 KXS21696.1 - 1.5e-11 43.7 4.8 2.3e-11 43.1 0.8 2.7 2 0 0 2 2 2 1 WH2 motif Ceramidase PF05875.12 KXS21697.1 - 3.8e-34 118.3 8.7 5e-34 117.9 8.7 1.1 1 0 0 1 1 1 1 Ceramidase DUF202 PF02656.15 KXS21697.1 - 0.57 10.7 10.7 2.8 8.4 0.5 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF202) CBS PF00571.28 KXS21698.1 - 5.6e-06 26.7 0.1 1.5 9.3 0.0 4.3 5 0 0 5 5 5 3 CBS domain MFS_1 PF07690.16 KXS21699.1 - 2.7e-40 138.4 48.7 2.2e-38 132.1 48.4 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KXS21699.1 - 6.2 5.0 14.5 0.73 8.0 2.1 2.6 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family RRM_1 PF00076.22 KXS21700.1 - 4.1e-30 103.4 0.0 2.9e-16 59.0 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PUF PF00806.19 KXS21700.1 - 1.1e-21 75.2 3.0 8.2e-05 22.1 0.0 6.2 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat RRM_occluded PF16842.5 KXS21700.1 - 3.4e-07 30.0 0.0 0.016 15.1 0.0 2.5 2 0 0 2 2 2 2 Occluded RNA-recognition motif RRM_5 PF13893.6 KXS21700.1 - 0.00069 19.2 0.0 0.0016 18.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SET_assoc PF11767.8 KXS21700.1 - 0.023 14.3 0.1 2.3 7.9 0.0 2.9 3 0 0 3 3 3 0 Histone lysine methyltransferase SET associated PPR PF01535.20 KXS21701.1 - 5.3e-22 76.5 0.1 0.025 14.8 0.0 10.0 11 0 0 11 11 11 5 PPR repeat PPR_2 PF13041.6 KXS21701.1 - 4.8e-21 74.7 0.0 0.00054 20.1 0.0 9.2 7 3 3 10 10 10 6 PPR repeat family PPR_1 PF12854.7 KXS21701.1 - 1.1e-12 47.4 0.0 0.00032 20.3 0.0 6.4 6 0 0 6 6 6 3 PPR repeat PPR_3 PF13812.6 KXS21701.1 - 2.3e-07 30.8 0.0 0.0002 21.4 0.0 4.1 5 0 0 5 5 5 1 Pentatricopeptide repeat domain PPR_long PF17177.4 KXS21701.1 - 0.002 17.5 0.0 0.96 8.8 0.0 3.5 3 0 0 3 3 3 1 Pentacotripeptide-repeat region of PRORP TPR_16 PF13432.6 KXS21701.1 - 0.55 10.9 6.0 40 5.0 2.8 4.2 3 1 0 3 3 3 0 Tetratricopeptide repeat Abhydrolase_6 PF12697.7 KXS21702.1 - 2.8e-08 34.6 0.0 3.5e-08 34.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXS21702.1 - 4.8e-06 26.4 0.0 6.1e-05 22.8 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase PF07224.11 KXS21702.1 - 0.059 12.4 0.0 0.087 11.8 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Abhydro_lipase PF04083.16 KXS21702.1 - 0.11 12.1 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region Aurora-A_bind PF09041.10 KXS21702.1 - 0.17 12.0 0.1 2 8.5 0.0 2.2 2 0 0 2 2 2 0 Aurora-A binding Pkinase PF00069.25 KXS21703.1 - 1e-57 195.5 0.0 4.7e-57 193.4 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS21703.1 - 1.9e-27 96.2 0.0 6.2e-19 68.3 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KXS21703.1 - 0.0015 18.5 0.1 0.0041 17.1 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KXS21703.1 - 0.01 15.2 0.0 0.025 14.0 0.0 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KXS21703.1 - 0.086 12.1 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 KXS21703.1 - 0.093 11.5 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase WD-3 PF09765.9 KXS21705.1 - 7.9e-57 192.8 0.0 9.2e-57 192.6 0.0 1.0 1 0 0 1 1 1 1 WD-repeat region FANCL_C PF11793.8 KXS21705.1 - 1.8e-22 79.3 0.6 3.1e-22 78.5 0.6 1.3 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING_2 PF13639.6 KXS21705.1 - 0.00039 20.7 6.7 0.00045 20.5 2.2 2.3 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 KXS21705.1 - 0.0014 18.9 3.4 0.0036 17.5 3.4 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain DRIM PF07539.12 KXS21705.1 - 0.16 10.2 0.0 0.47 8.7 0.0 1.6 2 0 0 2 2 2 0 Down-regulated in metastasis zf-ANAPC11 PF12861.7 KXS21705.1 - 0.58 10.3 5.4 2.6 8.1 5.4 2.1 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING-like PF08746.11 KXS21705.1 - 2.2 8.7 4.4 7.4 7.0 4.4 1.9 1 1 0 1 1 1 0 RING-like domain Cation_efflux PF01545.21 KXS21706.1 - 1.8e-45 155.1 9.3 2.3e-45 154.8 9.3 1.1 1 0 0 1 1 1 1 Cation efflux family Peptidase_S31 PF05578.12 KXS21706.1 - 0.1 12.1 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Pestivirus NS3 polyprotein peptidase S31 SH3_9 PF14604.6 KXS21707.1 - 1.1e-08 34.8 0.0 2.8e-08 33.5 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 KXS21707.1 - 3e-05 23.5 0.0 5.4e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 SH3 domain FUN14 PF04930.15 KXS21707.1 - 0.046 14.1 0.0 0.098 13.1 0.0 1.6 1 0 0 1 1 1 0 FUN14 family Zn_clus PF00172.18 KXS21708.1 - 2.8e-07 30.6 10.2 4.1e-07 30.0 10.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXS21708.1 - 0.0089 15.1 0.0 0.013 14.5 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF768 PF05589.11 KXS21708.1 - 0.097 12.7 0.0 8.9 6.4 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF768) Ank_2 PF12796.7 KXS21710.1 - 1.4e-07 32.0 0.1 0.0045 17.6 0.0 3.5 2 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXS21710.1 - 0.0014 19.0 1.0 14 6.6 0.0 4.4 4 0 0 4 4 4 1 Ankyrin repeat Ank_4 PF13637.6 KXS21710.1 - 0.0014 19.2 0.0 0.17 12.5 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXS21710.1 - 0.0051 17.1 0.2 0.84 10.0 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeats (many copies) TIM21 PF08294.11 KXS21712.1 - 1.9e-22 79.7 0.0 2.6e-22 79.3 0.0 1.2 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.10 KXS21712.1 - 0.094 12.5 0.0 0.24 11.1 0.0 1.6 1 1 0 1 1 1 0 Cytochrome oxidase complex assembly protein 1 4HBT_3 PF13622.6 KXS21713.1 - 5.7e-18 66.1 0.0 9.3e-18 65.4 0.0 1.3 1 1 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 KXS21713.1 - 0.064 13.6 0.1 0.87 10.0 0.0 2.6 3 0 0 3 3 3 0 Thioesterase superfamily Mito_carr PF00153.27 KXS21714.1 - 6.4e-53 176.7 7.0 1.8e-21 75.9 0.1 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 KXS21714.1 - 1.8e-20 73.2 3.9 2.1e-10 40.9 1.7 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KXS21714.1 - 1.1e-18 65.2 3.9 0.0001 21.6 0.0 4.5 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 KXS21714.1 - 2.2e-17 61.4 5.9 0.00029 20.5 1.6 4.5 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 KXS21714.1 - 4.7e-12 44.8 1.1 0.0015 17.9 0.0 3.6 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 KXS21714.1 - 6.5e-07 29.1 3.7 0.14 12.0 0.0 4.4 2 1 2 4 4 4 2 EF-hand domain pair EF-hand_10 PF14788.6 KXS21714.1 - 3e-05 23.8 1.6 0.86 9.5 0.1 3.9 3 1 1 4 4 4 3 EF hand SPARC_Ca_bdg PF10591.9 KXS21714.1 - 0.016 15.5 0.1 3.3 8.0 0.0 3.1 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DUF348 PF03990.14 KXS21714.1 - 0.032 14.0 0.4 0.12 12.1 0.4 2.0 1 0 0 1 1 1 0 G5-linked-Ubiquitin-like domain DUF3764 PF12594.8 KXS21714.1 - 0.087 12.9 0.1 54 3.9 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3764) EF-hand_4 PF12763.7 KXS21714.1 - 0.12 12.3 0.1 0.47 10.4 0.2 1.9 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand DUF3209 PF11483.8 KXS21714.1 - 0.14 12.6 0.0 0.3 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3209) EF-hand_9 PF14658.6 KXS21714.1 - 0.15 12.4 0.0 8.6 6.8 0.0 2.6 2 0 0 2 2 2 0 EF-hand domain BOP1NT PF08145.12 KXS21716.1 - 1.1e-95 320.5 1.1 1.4e-95 320.1 1.1 1.2 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.32 KXS21716.1 - 5.5e-18 65.0 9.8 0.0012 19.6 0.1 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXS21716.1 - 1.1e-07 32.0 0.0 0.19 12.0 0.0 5.1 4 2 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KXS21716.1 - 5.3e-05 22.3 0.0 0.00032 19.8 0.0 1.9 2 0 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein YL1 PF05764.13 KXS21716.1 - 7.2 6.7 10.9 7.1 6.7 9.7 1.6 1 1 0 1 1 1 0 YL1 nuclear protein DDOST_48kD PF03345.14 KXS21717.1 - 0.34 9.7 0.0 0.59 8.9 0.0 1.3 1 0 0 1 1 1 0 Oligosaccharyltransferase 48 kDa subunit beta AAA PF00004.29 KXS21718.1 - 1.6e-74 248.6 0.0 4.7e-35 120.9 0.0 3.5 3 0 0 3 3 3 3 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KXS21718.1 - 3.4e-19 68.4 4.4 4.2e-13 48.9 0.4 2.6 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 KXS21718.1 - 7.2e-13 49.3 0.5 1.6e-08 35.1 0.1 2.8 3 1 0 3 3 2 2 AAA ATPase domain RuvB_N PF05496.12 KXS21718.1 - 2.1e-10 40.6 1.5 0.0022 17.7 0.0 4.0 4 1 0 4 4 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 KXS21718.1 - 1.5e-09 38.3 0.0 2.5e-07 31.0 0.0 3.3 4 0 0 4 4 3 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 KXS21718.1 - 2e-09 37.6 1.5 0.0016 18.4 0.1 4.0 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 KXS21718.1 - 6.5e-08 32.4 0.4 0.017 14.7 0.1 3.3 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.6 KXS21718.1 - 4.3e-07 30.3 0.0 0.00034 20.9 0.0 3.2 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KXS21718.1 - 6.5e-07 29.6 0.1 0.0042 17.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.13 KXS21718.1 - 8.8e-07 28.4 0.0 0.052 12.8 0.0 3.0 3 0 0 3 3 3 2 TIP49 P-loop domain RNA_helicase PF00910.22 KXS21718.1 - 1.4e-06 28.6 0.0 0.018 15.4 0.0 2.5 2 0 0 2 2 2 2 RNA helicase Mg_chelatase PF01078.21 KXS21718.1 - 4.7e-06 26.1 0.4 0.023 14.1 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 KXS21718.1 - 8.1e-06 26.4 0.0 0.0023 18.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KXS21718.1 - 1.2e-05 25.1 0.0 0.018 14.8 0.0 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_28 PF13521.6 KXS21718.1 - 1.6e-05 25.2 0.0 0.029 14.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_3 PF07726.11 KXS21718.1 - 5.2e-05 23.1 0.0 0.52 10.2 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KXS21718.1 - 6.8e-05 22.6 0.0 0.0045 16.7 0.0 2.8 2 1 0 2 2 2 1 Sigma-54 interaction domain ATPase PF06745.13 KXS21718.1 - 0.0002 20.8 0.0 0.55 9.5 0.0 2.6 2 0 0 2 2 2 2 KaiC TsaE PF02367.17 KXS21718.1 - 0.00025 21.0 0.0 0.092 12.7 0.0 2.3 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 KXS21718.1 - 0.00044 20.2 0.0 0.018 15.0 0.0 2.6 2 0 0 2 2 2 1 NACHT domain Rad17 PF03215.15 KXS21718.1 - 0.00077 19.4 0.0 0.099 12.6 0.0 2.3 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_11 PF13086.6 KXS21718.1 - 0.00082 19.2 0.0 0.055 13.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KXS21718.1 - 0.0012 18.4 0.0 1.4 8.4 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region Parvo_NS1 PF01057.17 KXS21718.1 - 0.0052 15.9 0.0 0.35 9.9 0.0 2.2 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 AAA_30 PF13604.6 KXS21718.1 - 0.0056 16.4 2.0 0.027 14.2 0.0 2.8 3 0 0 3 3 3 1 AAA domain Sigma54_activ_2 PF14532.6 KXS21718.1 - 0.0063 16.6 0.0 5.3 7.2 0.0 2.8 3 0 0 3 3 2 0 Sigma-54 interaction domain PhoH PF02562.16 KXS21718.1 - 0.035 13.6 0.0 1.5 8.3 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein AAA_24 PF13479.6 KXS21718.1 - 0.035 13.8 0.0 0.78 9.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain Hydin_ADK PF17213.3 KXS21718.1 - 0.048 13.9 1.1 1.1 9.5 0.0 2.8 3 0 0 3 3 2 0 Hydin Adenylate kinase-like domain Vps4_C PF09336.10 KXS21718.1 - 0.055 13.5 0.1 0.3 11.1 0.0 2.3 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain ABC_tran PF00005.27 KXS21718.1 - 0.058 13.9 0.0 3 8.4 0.0 2.5 2 0 0 2 2 2 0 ABC transporter Zeta_toxin PF06414.12 KXS21718.1 - 0.075 12.3 0.0 1.2 8.4 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_19 PF13245.6 KXS21718.1 - 0.093 13.1 0.7 0.77 10.1 0.0 2.8 3 0 0 3 3 2 0 AAA domain DUF2075 PF09848.9 KXS21718.1 - 0.13 11.5 0.0 0.28 10.4 0.0 1.5 2 0 0 2 2 1 0 Uncharacterized conserved protein (DUF2075) SKI PF01202.22 KXS21718.1 - 0.15 12.2 0.1 4.1 7.5 0.0 2.5 2 0 0 2 2 2 0 Shikimate kinase Cytidylate_kin2 PF13189.6 KXS21718.1 - 0.16 12.1 0.0 3.5 7.7 0.0 2.6 2 0 0 2 2 2 0 Cytidylate kinase-like family Fungal_trans PF04082.18 KXS21719.1 - 6.3e-12 45.1 0.0 1.8e-11 43.6 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXS21719.1 - 7.3e-09 35.6 10.1 1.2e-08 34.9 10.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PSCyt3 PF07627.11 KXS21719.1 - 0.11 12.7 0.8 0.31 11.3 0.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1588) Fungal_trans PF04082.18 KXS21720.1 - 1.5e-05 24.2 0.0 2.5e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXS21721.1 - 7.1e-09 35.7 12.6 1.1e-08 35.0 12.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXS21721.1 - 8.5e-06 25.0 0.0 1.1e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Tam41_Mmp37 PF09139.11 KXS21722.1 - 9.1e-94 314.5 0.0 1.1e-93 314.3 0.0 1.0 1 0 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial Alba PF01918.21 KXS21723.1 - 0.12 12.3 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Alba Steroid_dh PF02544.16 KXS21724.1 - 0.029 14.4 0.1 0.056 13.4 0.1 1.4 1 0 0 1 1 1 0 3-oxo-5-alpha-steroid 4-dehydrogenase GATase PF00117.28 KXS21725.1 - 3.5e-09 36.7 0.0 0.0005 19.9 0.0 3.3 3 0 0 3 3 3 3 Glutamine amidotransferase class-I SKG6 PF08693.10 KXS21727.1 - 7.7e-05 22.0 2.0 0.00015 21.1 2.0 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF1518 PF07469.12 KXS21727.1 - 0.0004 20.7 7.7 0.0004 20.7 7.7 3.3 3 0 0 3 3 3 1 Domain of unknown function (DUF1518) SH3_9 PF14604.6 KXS21727.1 - 0.0049 16.7 0.1 0.013 15.4 0.1 1.8 1 0 0 1 1 1 1 Variant SH3 domain MDH PF02315.16 KXS21727.1 - 0.0065 16.5 1.9 20 5.3 0.0 3.6 3 0 0 3 3 3 2 Methanol dehydrogenase beta subunit Pox_LP_H2 PF03356.15 KXS21727.1 - 0.51 10.2 2.4 1.6 8.6 0.0 2.6 2 1 0 2 2 2 0 Viral late protein H2 adh_short PF00106.25 KXS21729.1 - 4.8e-40 137.1 0.3 9e-40 136.2 0.3 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXS21729.1 - 1.1e-39 136.4 0.3 1.6e-39 135.9 0.3 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXS21729.1 - 2.8e-06 27.4 0.0 5e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KXS21729.1 - 0.073 12.9 0.2 0.15 11.9 0.2 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 KXS21729.1 - 0.085 13.3 0.3 0.18 12.2 0.3 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Metallophos PF00149.28 KXS21730.1 - 3.9e-34 119.0 0.1 9.2e-34 117.7 0.0 1.7 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase DUF5378 PF17349.2 KXS21730.1 - 0.043 13.1 0.0 0.065 12.6 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5378) Cation_ATPase_C PF00689.21 KXS21731.1 - 2e-25 89.5 2.0 4e-25 88.6 2.0 1.5 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KXS21731.1 - 1.3e-17 64.8 9.2 1.8e-15 57.8 9.2 3.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KXS21731.1 - 1.9e-10 40.5 0.2 5e-10 39.2 0.2 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KXS21731.1 - 0.00026 20.8 0.2 0.075 12.8 0.2 2.1 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KXS21731.1 - 0.011 15.8 0.0 0.018 15.1 0.0 1.3 1 0 0 1 1 1 0 Cation transport ATPase (P-type) Transglut_core PF01841.19 KXS21731.1 - 0.14 12.6 0.0 0.34 11.4 0.0 1.6 1 0 0 1 1 1 0 Transglutaminase-like superfamily MFS_1 PF07690.16 KXS21732.1 - 1.7e-25 89.7 37.0 6.2e-21 74.7 29.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KXS21732.1 - 5.5e-06 25.2 13.0 0.00039 19.1 1.7 3.0 2 1 1 3 3 3 2 MFS/sugar transport protein Sugar_tr PF00083.24 KXS21732.1 - 0.0008 18.4 5.4 0.0016 17.4 3.0 2.1 1 1 1 2 2 2 1 Sugar (and other) transporter MFS_5 PF05631.14 KXS21732.1 - 0.0057 15.6 0.1 0.0099 14.8 0.1 1.4 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1_like PF12832.7 KXS21732.1 - 0.018 13.9 6.3 0.05 12.5 3.3 2.4 1 1 0 2 2 2 0 MFS_1 like family OATP PF03137.20 KXS21732.1 - 0.038 12.3 3.3 0.68 8.1 0.1 2.5 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family AZUL PF16558.5 KXS21733.1 - 0.02 15.2 0.2 0.049 13.9 0.2 1.6 1 0 0 1 1 1 0 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A Rib_recp_KP_reg PF05104.12 KXS21734.1 - 2.9 8.9 4.0 4.3 8.4 4.0 1.1 1 0 0 1 1 1 0 Ribosome receptor lysine/proline rich region BLOC1_2 PF10046.9 KXS21735.1 - 7e-20 71.1 0.5 8.1e-20 70.9 0.5 1.0 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 HrpB4 PF09502.10 KXS21735.1 - 0.0083 16.0 0.0 0.011 15.6 0.0 1.2 1 1 0 1 1 1 1 Bacterial type III secretion protein (HrpB4) Sec34 PF04136.15 KXS21735.1 - 0.032 14.1 0.2 0.051 13.5 0.2 1.3 1 1 0 1 1 1 0 Sec34-like family CENP-Q PF13094.6 KXS21735.1 - 0.054 13.7 2.2 0.73 10.0 0.3 2.0 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit IFT57 PF10498.9 KXS21735.1 - 0.075 12.0 0.2 0.096 11.6 0.2 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 CCDC142 PF14923.6 KXS21735.1 - 0.1 11.3 0.0 0.11 11.2 0.0 1.0 1 0 0 1 1 1 0 Coiled-coil protein 142 DUF3533 PF12051.8 KXS21737.1 - 4.7e-18 65.3 7.7 4.7e-18 65.3 7.7 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3533) bZIP_1 PF00170.21 KXS21738.1 - 0.00036 20.6 10.0 0.00095 19.2 10.0 1.7 1 0 0 1 1 1 1 bZIP transcription factor Atg14 PF10186.9 KXS21738.1 - 0.015 14.4 2.7 0.59 9.2 2.3 2.1 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Gp-FAR-1 PF05823.12 KXS21738.1 - 0.056 13.8 0.2 8.9 6.7 0.0 2.4 2 0 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Zwint PF15556.6 KXS21738.1 - 0.43 10.0 9.5 0.76 9.2 8.5 1.8 2 0 0 2 2 2 0 ZW10 interactor CTP_transf_like PF01467.26 KXS21739.1 - 1.4e-30 106.4 0.0 1.9e-30 105.9 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase-like DUF5639 PF18690.1 KXS21739.1 - 0.0072 16.5 0.0 0.014 15.5 0.0 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF5639) DUF5499 PF17603.2 KXS21739.1 - 0.1 13.2 0.0 0.28 11.8 0.0 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5499) S1 PF00575.23 KXS21740.1 - 3.4e-67 222.8 36.4 5.6e-13 49.0 0.3 12.3 12 0 0 12 12 12 9 S1 RNA binding domain Suf PF05843.14 KXS21740.1 - 1.9e-07 31.4 8.4 4e-06 27.0 0.0 3.8 1 1 2 3 3 3 2 Suppressor of forked protein (Suf) NRDE-2 PF08424.10 KXS21740.1 - 1.5e-05 24.3 1.1 0.035 13.2 0.1 3.1 1 1 1 2 2 2 2 NRDE-2, necessary for RNA interference TPR_14 PF13428.6 KXS21740.1 - 7.1e-05 23.3 0.0 6.7 7.8 0.0 4.7 1 1 4 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 KXS21740.1 - 0.0011 19.4 0.0 0.21 12.1 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_15 PF13429.6 KXS21740.1 - 0.051 12.8 0.2 0.28 10.4 0.4 2.1 2 1 1 3 3 3 0 Tetratricopeptide repeat Acetyltransf_2 PF00797.17 KXS21741.1 - 1.3e-27 97.2 0.0 1.1e-21 77.7 0.0 2.9 2 1 0 2 2 2 2 N-acetyltransferase tRNA_synthFbeta PF17759.1 KXS21742.1 - 1.1e-48 165.5 0.0 1.8e-48 164.8 0.0 1.3 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 KXS21742.1 - 5.8e-27 93.7 0.0 1.5e-26 92.4 0.0 1.8 2 0 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 KXS21742.1 - 3.2e-18 66.0 0.0 6.5e-18 65.0 0.0 1.5 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 KXS21742.1 - 6.7e-17 61.6 0.0 4.8e-14 52.4 0.0 2.7 2 0 0 2 2 2 2 tRNA synthetase B5 domain tRNA-synt_2d PF01409.20 KXS21742.1 - 0.013 15.0 0.0 0.037 13.5 0.0 1.8 1 1 0 1 1 1 0 tRNA synthetases class II core domain (F) AMP-binding PF00501.28 KXS21743.1 - 5.3e-63 213.1 0.0 7.4e-63 212.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXS21743.1 - 0.0011 19.9 0.0 0.0024 18.8 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain HMGL-like PF00682.19 KXS21745.1 - 5.9e-80 268.6 0.5 1e-79 267.8 0.5 1.4 1 0 0 1 1 1 1 HMGL-like Oxidored_FMN PF00724.20 KXS21745.1 - 0.043 13.1 0.1 0.5 9.6 0.1 2.1 1 1 0 1 1 1 0 NADH:flavin oxidoreductase / NADH oxidase family Homeobox_KN PF05920.11 KXS21746.1 - 1.8e-15 56.5 0.3 5.5e-15 55.0 0.3 1.9 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 KXS21746.1 - 0.00077 19.3 0.1 0.0017 18.1 0.1 1.6 1 0 0 1 1 1 1 Homeodomain Homez PF11569.8 KXS21746.1 - 0.0058 16.1 0.1 0.15 11.5 0.0 2.7 3 0 0 3 3 3 1 Homeodomain leucine-zipper encoding, Homez AAA_6 PF12774.7 KXS21750.1 - 1e-156 521.0 0.0 1.4e-155 517.2 0.0 2.7 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 KXS21750.1 - 7.3e-143 476.4 3.0 7.3e-143 476.4 3.0 4.2 5 1 1 6 6 5 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 KXS21750.1 - 4.6e-115 384.0 0.1 4.6e-115 384.0 0.1 2.5 3 0 0 3 3 3 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 KXS21750.1 - 4.6e-105 350.6 2.7 3e-103 344.7 0.0 4.5 5 0 0 5 5 5 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 KXS21750.1 - 1.6e-91 305.4 0.0 3.8e-90 300.8 0.1 3.1 2 0 0 2 2 2 1 ATP-binding dynein motor region AAA_7 PF12775.7 KXS21750.1 - 2.6e-82 274.7 0.6 6.8e-77 257.1 0.0 3.5 3 0 0 3 3 3 3 P-loop containing dynein motor region AAA_lid_11 PF18198.1 KXS21750.1 - 1.2e-60 204.1 1.0 1.3e-59 200.7 0.2 2.6 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain MT PF12777.7 KXS21750.1 - 8.1e-54 182.9 5.6 1.5e-53 182.0 5.6 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 KXS21750.1 - 4.5e-45 152.6 0.0 3.6e-43 146.4 0.0 3.2 3 0 0 3 3 2 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 KXS21750.1 - 4.3e-31 107.7 0.0 2.1e-30 105.5 0.0 2.3 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 KXS21750.1 - 8.3e-20 71.2 0.0 1.9e-06 27.9 0.0 5.8 4 2 1 5 5 5 3 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 KXS21750.1 - 2.4e-19 69.4 0.0 1.1e-18 67.3 0.0 2.2 1 0 0 1 1 1 1 AAA+ lid domain AAA PF00004.29 KXS21750.1 - 1.2e-08 35.5 1.3 0.11 12.9 0.0 5.0 5 0 0 5 5 4 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KXS21750.1 - 4.7e-08 33.4 0.1 0.6 10.4 0.0 5.5 4 0 0 4 4 4 2 AAA domain AAA_16 PF13191.6 KXS21750.1 - 1.8e-07 31.7 0.0 0.52 10.7 0.0 5.4 4 0 0 4 4 4 2 AAA ATPase domain DUF853 PF05872.12 KXS21750.1 - 3.5e-06 25.9 0.2 0.1 11.2 0.0 3.4 3 0 0 3 3 3 2 Bacterial protein of unknown function (DUF853) Sigma54_activat PF00158.26 KXS21750.1 - 1.4e-05 24.9 0.1 0.021 14.5 0.0 3.8 4 0 0 4 4 4 1 Sigma-54 interaction domain RNA_helicase PF00910.22 KXS21750.1 - 0.00044 20.6 0.3 8.9 6.8 0.0 3.8 3 0 0 3 3 3 0 RNA helicase AAA_30 PF13604.6 KXS21750.1 - 0.00071 19.3 0.3 1.5 8.5 0.1 3.5 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 KXS21750.1 - 0.0014 19.2 0.2 0.59 10.7 0.0 4.1 3 0 0 3 3 3 1 AAA domain Rad17 PF03215.15 KXS21750.1 - 0.0049 16.8 1.8 31 4.4 0.0 4.4 4 1 0 4 4 3 0 Rad17 P-loop domain ResIII PF04851.15 KXS21750.1 - 0.0056 16.7 0.0 1.4 8.9 0.0 3.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_33 PF13671.6 KXS21750.1 - 0.0063 16.7 0.3 34 4.6 0.0 4.1 3 0 0 3 3 3 0 AAA domain DUF4527 PF15030.6 KXS21750.1 - 0.01 15.3 0.3 0.027 13.9 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4527) FtsK_SpoIIIE PF01580.18 KXS21750.1 - 0.019 14.4 1.4 6.9 5.9 0.0 4.0 4 0 0 4 4 4 0 FtsK/SpoIIIE family KorB PF08535.10 KXS21750.1 - 0.023 14.7 0.5 0.12 12.4 0.2 2.4 2 0 0 2 2 1 0 KorB domain AAA_19 PF13245.6 KXS21750.1 - 0.043 14.1 0.7 47 4.3 0.0 4.5 5 0 0 5 5 3 0 AAA domain ABC_tran PF00005.27 KXS21750.1 - 0.047 14.2 3.3 2.5 8.6 0.0 4.0 4 0 0 4 4 3 0 ABC transporter Mg_chelatase PF01078.21 KXS21750.1 - 0.059 12.7 1.7 3.8 6.8 0.0 3.6 5 0 0 5 5 4 0 Magnesium chelatase, subunit ChlI Sirohm_synth_C PF14823.6 KXS21750.1 - 0.23 11.1 1.0 2.3 7.9 0.3 3.1 2 0 0 2 2 2 0 Sirohaem biosynthesis protein C-terminal DUF815 PF05673.13 KXS21750.1 - 0.23 10.6 2.3 2.7 7.1 0.0 3.6 5 0 0 5 5 5 0 Protein of unknown function (DUF815) TsaE PF02367.17 KXS21750.1 - 0.49 10.4 1.8 12 5.9 0.1 3.3 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SRP54 PF00448.22 KXS21750.1 - 0.58 9.8 2.5 24 4.5 0.1 3.1 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain NuA4 PF09340.10 KXS21750.1 - 1.3 9.0 4.2 0.56 10.1 0.8 2.3 2 0 0 2 2 1 0 Histone acetyltransferase subunit NuA4 T3SSipB PF16535.5 KXS21750.1 - 3.4 8.1 11.0 23 5.4 3.5 3.3 2 0 0 2 2 2 0 Type III cell invasion protein SipB T2SSE PF00437.20 KXS21750.1 - 3.6 6.6 8.4 5.6 5.9 0.0 3.6 5 0 0 5 5 5 0 Type II/IV secretion system protein HMG_box PF00505.19 KXS21752.1 - 7.6e-06 26.3 1.6 1.6e-05 25.2 1.6 1.5 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KXS21752.1 - 2.1e-05 25.0 0.2 3.7e-05 24.2 0.2 1.4 1 0 0 1 1 1 1 HMG-box domain Coat_F PF07875.12 KXS21752.1 - 0.0018 18.5 0.2 0.0031 17.7 0.2 1.3 1 0 0 1 1 1 1 Coat F domain DOMON PF03351.17 KXS21753.1 - 0.0043 17.3 0.0 0.0064 16.7 0.0 1.3 1 0 0 1 1 1 1 DOMON domain GST_N PF02798.20 KXS21754.1 - 1.9e-22 79.4 0.0 2.8e-22 78.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KXS21754.1 - 2.7e-18 66.1 0.0 1.7e-17 63.6 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KXS21754.1 - 1.7e-15 57.1 0.0 4.5e-15 55.7 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KXS21754.1 - 1.8e-08 34.5 0.0 2.7e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KXS21754.1 - 9.8e-06 25.5 0.0 1.4e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Ribosomal_L5e PF17144.4 KXS21756.1 - 2.7e-75 251.8 0.0 2.7e-75 251.8 0.0 2.8 3 0 0 3 3 3 2 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 KXS21756.1 - 1.5e-30 105.9 12.9 3.3e-30 104.9 12.9 1.6 1 0 0 1 1 1 1 Ribosomal L18 C-terminal region DAG_kinase_N PF14513.6 KXS21756.1 - 0.16 12.2 4.6 0.28 11.4 4.6 1.3 1 0 0 1 1 1 0 Diacylglycerol kinase N-terminus ECH_1 PF00378.20 KXS21757.1 - 3.6e-37 128.0 0.0 4.9e-37 127.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXS21757.1 - 5.1e-22 78.8 0.0 8e-20 71.6 0.0 2.2 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Aminotran_1_2 PF00155.21 KXS21758.1 - 3.5e-19 69.2 0.0 4.5e-19 68.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 KXS21758.1 - 9.4e-07 28.0 0.0 1.2e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase TPR_19 PF14559.6 KXS21759.1 - 2.7e-16 59.8 10.6 0.00039 20.9 0.4 8.4 8 1 1 9 9 8 4 Tetratricopeptide repeat TPR_8 PF13181.6 KXS21759.1 - 6.9e-15 54.0 7.1 0.0064 16.6 0.0 8.3 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_14 PF13428.6 KXS21759.1 - 1.8e-11 43.8 14.1 0.85 10.6 0.0 10.8 7 2 4 11 11 11 2 Tetratricopeptide repeat TPR_11 PF13414.6 KXS21759.1 - 1.1e-09 37.8 0.4 0.00011 21.8 0.0 4.5 4 0 0 4 4 4 2 TPR repeat TPR_2 PF07719.17 KXS21759.1 - 3e-09 36.3 10.9 0.18 12.0 0.0 9.0 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_17 PF13431.6 KXS21759.1 - 3.1e-07 30.3 3.4 0.26 11.8 0.0 6.2 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 KXS21759.1 - 4.8e-07 29.3 6.3 0.047 13.5 0.0 5.1 6 0 0 6 6 5 2 Tetratricopeptide repeat BTAD PF03704.17 KXS21759.1 - 3.2e-06 27.6 11.4 0.00059 20.3 0.4 4.3 4 0 0 4 4 3 1 Bacterial transcriptional activator domain TPR_16 PF13432.6 KXS21759.1 - 3.6e-06 27.5 10.0 0.37 11.5 0.0 7.1 7 0 0 7 7 6 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KXS21759.1 - 6e-06 26.4 3.7 0.87 9.9 0.1 6.2 5 2 1 6 6 6 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 KXS21759.1 - 3.2e-05 23.6 11.8 0.15 12.1 0.0 7.3 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_12 PF13424.6 KXS21759.1 - 0.00017 21.8 15.9 2.9 8.3 0.1 8.2 8 1 1 9 9 8 1 Tetratricopeptide repeat TPR_20 PF14561.6 KXS21759.1 - 0.0012 19.2 1.2 2.2 8.6 0.2 3.9 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_15 PF13429.6 KXS21759.1 - 0.014 14.6 2.0 0.98 8.6 0.6 3.8 2 1 1 3 3 3 0 Tetratricopeptide repeat NatB_MDM20 PF09797.9 KXS21759.1 - 0.019 13.9 0.0 0.037 13.0 0.0 1.4 1 0 0 1 1 1 0 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_6 PF13174.6 KXS21759.1 - 0.24 12.1 6.5 1.2e+02 3.6 0.0 6.9 9 0 0 9 9 7 0 Tetratricopeptide repeat Hira PF07569.11 KXS21760.1 - 6.7e-37 127.4 0.0 1.4e-36 126.3 0.0 1.6 1 1 0 1 1 1 1 TUP1-like enhancer of split WD40 PF00400.32 KXS21760.1 - 5.4e-21 74.5 21.7 1.5e-05 25.6 2.0 7.7 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXS21760.1 - 5.4e-12 45.9 0.1 0.021 15.1 0.0 5.6 6 0 0 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain HIRA_B PF09453.10 KXS21760.1 - 2.8e-05 23.8 2.2 3.7e-05 23.4 0.1 2.4 2 0 0 2 2 2 1 HIRA B motif PD40 PF07676.12 KXS21760.1 - 0.011 15.6 3.4 19 5.3 0.0 4.4 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Mcl1_mid PF12341.8 KXS21760.1 - 0.024 14.0 0.0 0.059 12.7 0.0 1.6 2 0 0 2 2 2 0 Minichromosome loss protein, Mcl1, middle region Nbas_N PF15492.6 KXS21760.1 - 0.35 10.2 1.4 7.4 5.8 0.2 2.8 3 0 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal MFS_1 PF07690.16 KXS21761.1 - 6.6e-31 107.5 37.8 6.6e-31 107.5 37.8 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Uso1_p115_head PF04869.14 KXS21762.1 - 1.7e-70 237.6 0.0 5.3e-70 236.0 0.0 1.8 2 0 0 2 2 2 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.13 KXS21762.1 - 2.4e-10 40.9 5.0 4.6e-10 39.9 5.0 1.5 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, C terminal region Arm_vescicular PF18770.1 KXS21762.1 - 0.00011 22.0 2.0 0.00022 21.1 0.2 2.5 3 0 0 3 3 1 1 Armadillo tether-repeat of vescicular transport factor HEAT_2 PF13646.6 KXS21762.1 - 0.00017 21.9 0.3 0.012 16.0 0.0 4.2 4 1 0 4 4 3 1 HEAT repeats ATG16 PF08614.11 KXS21762.1 - 0.0014 18.9 9.8 0.13 12.4 2.2 2.5 2 0 0 2 2 2 2 Autophagy protein 16 (ATG16) DUF812 PF05667.11 KXS21762.1 - 0.0015 17.5 0.3 0.0025 16.8 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF812) TMF_DNA_bd PF12329.8 KXS21762.1 - 0.0016 18.4 4.9 0.079 13.0 0.6 2.6 2 0 0 2 2 2 1 TATA element modulatory factor 1 DNA binding Spc7 PF08317.11 KXS21762.1 - 0.0016 17.4 5.2 0.0025 16.8 0.9 2.2 2 0 0 2 2 2 1 Spc7 kinetochore protein RTP1_C1 PF10363.9 KXS21762.1 - 0.0022 18.2 0.1 0.56 10.4 0.0 3.4 3 1 0 3 3 2 1 Required for nuclear transport of RNA pol II C-terminus 1 ADIP PF11559.8 KXS21762.1 - 0.004 17.2 6.5 0.012 15.7 3.1 2.4 2 0 0 2 2 2 1 Afadin- and alpha -actinin-Binding Fez1 PF06818.15 KXS21762.1 - 0.0044 17.5 2.8 0.0081 16.6 2.8 1.3 1 0 0 1 1 1 1 Fez1 Tropomyosin_1 PF12718.7 KXS21762.1 - 0.0046 17.1 3.7 0.01 16.0 3.7 1.6 1 1 0 1 1 1 1 Tropomyosin like PspA_IM30 PF04012.12 KXS21762.1 - 0.023 14.3 4.2 0.13 11.9 1.2 2.3 2 0 0 2 2 2 0 PspA/IM30 family Exonuc_VII_L PF02601.15 KXS21762.1 - 0.026 14.1 2.3 0.043 13.4 2.3 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4407 PF14362.6 KXS21762.1 - 0.075 12.4 6.3 0.14 11.5 6.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HTH_1 PF00126.27 KXS21762.1 - 0.09 12.7 0.0 0.35 10.8 0.0 2.1 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family Tti2 PF10521.9 KXS21762.1 - 0.094 12.2 0.3 1.1 8.7 0.0 2.3 2 0 0 2 2 2 0 Tti2 family Yae1_N PF09811.9 KXS21762.1 - 0.12 12.1 0.4 0.24 11.1 0.4 1.5 1 0 0 1 1 1 0 Essential protein Yae1, N terminal GAS PF13851.6 KXS21762.1 - 0.17 11.2 5.7 1.6 8.1 5.7 2.1 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding USP8_interact PF08941.10 KXS21762.1 - 0.18 11.6 2.0 4.2 7.1 0.4 2.3 2 0 0 2 2 2 0 USP8 interacting TMF_TATA_bd PF12325.8 KXS21762.1 - 0.19 12.0 8.3 4.4 7.6 2.2 2.6 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Golgin_A5 PF09787.9 KXS21762.1 - 0.21 11.0 2.3 0.51 9.8 2.3 1.6 1 0 0 1 1 1 0 Golgin subfamily A member 5 CC2-LZ PF16516.5 KXS21762.1 - 0.29 11.5 6.2 0.36 11.2 1.2 2.5 2 0 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator FAM76 PF16046.5 KXS21762.1 - 0.33 10.3 1.9 0.37 10.1 0.1 1.8 2 0 0 2 2 2 0 FAM76 protein Cortex-I_coil PF09304.10 KXS21762.1 - 0.35 11.1 5.0 3.4 7.9 0.6 2.4 2 0 0 2 2 2 0 Cortexillin I, coiled coil Filament PF00038.21 KXS21762.1 - 0.36 10.4 5.8 0.21 11.1 1.0 2.1 2 0 0 2 2 2 0 Intermediate filament protein HEAT PF02985.22 KXS21762.1 - 0.37 11.2 2.9 13 6.4 0.0 4.2 4 0 0 4 4 3 0 HEAT repeat OmpH PF03938.14 KXS21762.1 - 0.4 11.0 5.4 0.58 10.5 1.2 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Med21 PF11221.8 KXS21762.1 - 0.5 10.6 8.6 5.4 7.3 0.1 3.5 3 0 0 3 3 3 0 Subunit 21 of Mediator complex ABC_tran_CTD PF16326.5 KXS21762.1 - 0.5 10.6 8.9 0.6 10.4 2.5 3.1 3 0 0 3 3 3 0 ABC transporter C-terminal domain MPS2 PF17060.5 KXS21762.1 - 0.55 9.4 4.5 9.9 5.3 1.1 2.2 1 1 1 2 2 2 0 Monopolar spindle protein 2 APG6_N PF17675.1 KXS21762.1 - 0.58 10.7 6.1 0.7 10.4 0.6 2.4 2 0 0 2 2 2 0 Apg6 coiled-coil region XhlA PF10779.9 KXS21762.1 - 0.75 10.0 2.7 4.9 7.4 0.0 2.6 2 0 0 2 2 2 0 Haemolysin XhlA FlaC_arch PF05377.11 KXS21762.1 - 0.86 10.0 3.0 35 4.9 0.6 2.9 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) MscS_porin PF12795.7 KXS21762.1 - 0.92 9.0 10.7 2.5 7.6 10.5 1.6 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain Sec2p PF06428.11 KXS21762.1 - 1.1 9.3 9.9 4.5 7.3 0.9 3.0 3 0 0 3 3 2 0 GDP/GTP exchange factor Sec2p KELK PF15796.5 KXS21762.1 - 1.6 9.2 8.1 1.1 9.8 0.8 2.6 2 0 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DnaJ PF00226.31 KXS21763.1 - 1.8e-23 82.4 0.0 3.2e-23 81.6 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain DUF1977 PF09320.11 KXS21763.1 - 3e-23 82.1 0.8 4.5e-23 81.5 0.1 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1977) PAP1 PF08601.10 KXS21763.1 - 1.2 8.8 8.0 1.7 8.3 8.0 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 SR-25 PF10500.9 KXS21763.1 - 1.6 8.3 15.8 2.8 7.5 15.8 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Apt1 PF10351.9 KXS21763.1 - 5 5.9 6.3 6.7 5.4 6.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain adh_short PF00106.25 KXS21764.1 - 1.3e-25 90.0 0.3 3.2e-24 85.5 0.1 2.0 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXS21764.1 - 1.8e-17 63.7 0.1 2.5e-17 63.2 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXS21764.1 - 6.6e-11 42.5 0.2 9.1e-11 42.0 0.2 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXS21764.1 - 0.00076 19.0 0.1 0.0013 18.2 0.1 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family peroxidase PF00141.23 KXS21765.1 - 2.9e-31 108.9 0.0 4.5e-31 108.3 0.0 1.3 1 1 0 1 1 1 1 Peroxidase MAJIN PF15077.6 KXS21766.1 - 0.92 9.3 6.8 0.31 10.8 2.7 2.2 2 0 0 2 2 2 0 Membrane-anchored junction protein DUF885 PF05960.11 KXS21767.1 - 2.1e-138 463.3 0.0 2.4e-138 463.1 0.0 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF885) AA_permease_2 PF13520.6 KXS21769.1 - 6.6e-44 150.4 38.6 7.8e-44 150.2 38.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXS21769.1 - 3e-17 62.4 35.5 4.4e-17 61.8 35.5 1.2 1 0 0 1 1 1 1 Amino acid permease Gram_pos_anchor PF00746.21 KXS21769.1 - 3.5 7.7 6.0 10 6.1 0.0 3.0 3 0 0 3 3 3 0 LPXTG cell wall anchor motif DICT PF10069.9 KXS21770.1 - 0.074 12.8 0.1 0.15 11.9 0.1 1.4 1 0 0 1 1 1 0 Sensory domain in DIguanylate Cyclases and Two-component system adh_short_C2 PF13561.6 KXS21771.1 - 1e-51 175.8 0.0 1.2e-51 175.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXS21771.1 - 1.1e-38 132.6 0.0 1.4e-38 132.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 KXS21771.1 - 0.00029 20.4 0.0 0.00042 19.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KXS21771.1 - 0.018 15.0 1.3 0.11 12.5 1.3 2.0 1 1 0 1 1 1 0 KR domain 3Beta_HSD PF01073.19 KXS21771.1 - 0.063 12.3 0.0 0.097 11.7 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KXS21771.1 - 0.093 12.1 0.0 0.2 11.0 0.0 1.5 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KXS21771.1 - 0.11 11.6 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Sugar_tr PF00083.24 KXS21772.1 - 1.1e-114 383.8 20.4 1.2e-114 383.6 20.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXS21772.1 - 3.6e-22 78.8 33.3 1.1e-21 77.1 32.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Peptidase_M36 PF02128.15 KXS21773.1 - 9.8e-95 317.8 1.2 1.1e-94 317.6 1.2 1.0 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) Peptidase_M4 PF01447.18 KXS21773.1 - 0.1 13.1 0.1 0.2 12.1 0.1 1.5 1 0 0 1 1 1 0 Thermolysin metallopeptidase, catalytic domain Hydrolase_4 PF12146.8 KXS21774.1 - 1.2e-22 80.3 0.0 1.8e-22 79.8 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KXS21774.1 - 1.7e-20 73.8 0.1 2.5e-18 66.7 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXS21774.1 - 1e-15 59.0 1.1 1.6e-15 58.3 1.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 KXS21774.1 - 3.3e-05 23.9 0.0 6e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_5 PF12695.7 KXS21774.1 - 0.0017 18.1 0.0 0.33 10.7 0.0 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase family Esterase PF00756.20 KXS21774.1 - 0.0086 15.7 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 1 Putative esterase zf-RNPHF PF08080.12 KXS21774.1 - 0.07 13.1 0.1 0.27 11.2 0.1 2.0 2 0 0 2 2 2 0 RNPHF zinc finger Avl9 PF09794.9 KXS21776.1 - 0.0004 19.2 0.0 0.00084 18.1 0.0 1.5 1 1 0 1 1 1 1 Transport protein Avl9 DENN PF02141.21 KXS21776.1 - 0.11 12.4 0.0 0.66 9.9 0.0 2.2 1 1 0 1 1 1 0 DENN (AEX-3) domain Fungal_trans PF04082.18 KXS21777.1 - 5.7e-20 71.5 0.9 1.2e-19 70.5 0.9 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXS21777.1 - 1.4e-07 31.5 8.2 2.1e-07 30.9 8.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CoA_transf_3 PF02515.17 KXS21778.1 - 1.8e-48 165.6 0.0 3.3e-42 144.9 0.0 2.8 3 0 0 3 3 3 2 CoA-transferase family III Methyltransf_8 PF05148.15 KXS21778.1 - 0.14 12.0 0.2 0.23 11.3 0.2 1.2 1 0 0 1 1 1 0 Hypothetical methyltransferase Spc7 PF08317.11 KXS21779.1 - 0.58 9.0 55.1 0.059 12.3 16.4 2.9 1 1 1 2 2 2 0 Spc7 kinetochore protein Hemagglutinin PF00509.18 KXS21779.1 - 0.82 8.0 7.2 4.1 5.7 0.6 2.2 2 0 0 2 2 2 0 Haemagglutinin Complex1_LYR PF05347.15 KXS21780.1 - 4.5e-07 29.8 0.0 8.3e-07 29.0 0.0 1.5 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KXS21780.1 - 0.003 18.3 0.0 0.0033 18.1 0.0 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Cupin_8 PF13621.6 KXS21781.1 - 7.1e-16 58.7 0.3 3.5e-12 46.6 0.1 2.1 1 1 1 2 2 2 2 Cupin-like domain JmjC PF02373.22 KXS21781.1 - 4.1e-13 49.7 0.2 5.5e-12 46.1 0.2 2.1 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_1 PF00190.22 KXS21781.1 - 0.011 15.4 0.0 0.017 14.7 0.0 1.2 1 0 0 1 1 1 0 Cupin Cupin_2 PF07883.11 KXS21781.1 - 0.053 13.3 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Cupin domain Cupin_4 PF08007.12 KXS21781.1 - 0.056 12.9 0.0 0.095 12.1 0.0 1.3 1 0 0 1 1 1 0 Cupin superfamily protein MTP18 PF10558.9 KXS21782.1 - 2.6e-55 187.0 7.1 8.4e-28 97.5 0.2 2.1 1 1 1 2 2 2 2 Mitochondrial 18 KDa protein (MTP18) CoatB PF10389.9 KXS21783.1 - 0.037 13.9 7.5 0.082 12.8 7.5 1.6 1 0 0 1 1 1 0 Bacteriophage coat protein B SH3_9 PF14604.6 KXS21784.1 - 9.4e-10 38.2 0.0 0.0016 18.3 0.0 2.8 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 KXS21784.1 - 9.3e-07 28.4 0.0 0.0062 16.1 0.0 2.5 2 0 0 2 2 2 2 SH3 domain LRR_8 PF13855.6 KXS21784.1 - 0.0026 17.5 0.6 0.0097 15.7 0.7 2.0 1 1 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 KXS21784.1 - 0.64 10.5 2.3 12 6.5 0.3 3.3 2 1 0 3 3 3 0 Leucine Rich repeats (2 copies) SH3_9 PF14604.6 KXS21785.1 - 1.3e-05 25.0 0.0 2e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXS21785.1 - 0.0003 20.3 0.0 0.0005 19.6 0.0 1.3 1 0 0 1 1 1 1 SH3 domain ATP_sub_h PF10775.9 KXS21787.1 - 2.6e-08 33.7 1.0 2.6e-08 33.7 1.0 1.7 2 0 0 2 2 2 1 ATP synthase complex subunit h adh_short_C2 PF13561.6 KXS21788.1 - 6.3e-56 189.5 2.5 3.4e-44 151.1 1.3 2.0 1 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXS21788.1 - 9.2e-48 162.3 2.0 1.1e-47 162.0 2.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXS21788.1 - 1.5e-16 60.8 0.2 2e-16 60.4 0.2 1.1 1 0 0 1 1 1 1 KR domain AdoHcyase_NAD PF00670.21 KXS21788.1 - 0.0064 16.6 0.2 0.017 15.2 0.2 1.7 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 3HCDH_N PF02737.18 KXS21788.1 - 0.008 16.1 0.2 0.013 15.4 0.2 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_25 PF13649.6 KXS21788.1 - 0.011 16.4 0.0 0.024 15.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain UDPG_MGDP_dh_N PF03721.14 KXS21788.1 - 0.071 12.7 0.2 0.14 11.7 0.2 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pkinase PF00069.25 KXS21789.1 - 1.2e-68 231.4 3.8 1.5e-67 227.8 3.8 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS21789.1 - 1.9e-43 148.6 1.0 8.9e-43 146.4 1.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 KXS21789.1 - 5.9e-06 26.0 1.8 9.9e-06 25.3 1.8 1.3 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 KXS21789.1 - 0.00013 21.0 0.2 0.00018 20.5 0.2 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 KXS21789.1 - 0.00033 19.6 0.1 0.0004 19.3 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KXS21789.1 - 0.0012 18.3 0.5 0.0021 17.5 0.1 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KXS21789.1 - 0.021 14.1 0.2 0.063 12.6 0.2 1.9 1 1 0 1 1 1 0 Kinase-like APH PF01636.23 KXS21789.1 - 0.054 13.4 1.4 1.2 9.0 0.2 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Synapsin PF02078.16 KXS21789.1 - 0.07 13.4 3.6 0.38 11.1 3.5 2.1 1 1 0 1 1 1 0 Synapsin, N-terminal domain Kin17_mid PF10357.9 KXS21789.1 - 0.44 10.5 5.6 0.82 9.6 1.7 2.4 2 1 0 2 2 2 0 Domain of Kin17 curved DNA-binding protein KA1 PF02149.19 KXS21790.1 - 8.4e-13 47.9 0.3 1.4e-12 47.2 0.1 1.5 2 0 0 2 2 2 1 Kinase associated domain 1 CPSF73-100_C PF11718.8 KXS21790.1 - 0.15 11.6 0.0 0.18 11.4 0.0 1.1 1 0 0 1 1 1 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Cornifin PF02389.15 KXS21792.1 - 0.0014 18.8 0.0 0.0027 17.9 0.0 1.5 1 0 0 1 1 1 1 Cornifin (SPRR) family FMO-like PF00743.19 KXS21793.1 - 3e-15 55.6 0.0 1e-14 53.9 0.0 1.9 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KXS21793.1 - 1.1e-09 38.4 0.0 1.6e-08 34.7 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KXS21793.1 - 4.3e-09 36.0 0.0 6e-08 32.2 0.0 2.5 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KXS21793.1 - 1.3e-05 24.6 0.4 0.00044 19.6 0.2 3.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXS21793.1 - 0.00014 21.2 0.0 0.00035 19.9 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXS21793.1 - 0.0076 16.2 0.0 0.35 10.8 0.0 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.17 KXS21793.1 - 0.0086 15.3 0.2 0.74 9.0 0.0 2.9 3 0 0 3 3 3 1 Thi4 family DAO PF01266.24 KXS21793.1 - 0.011 15.3 0.0 0.06 12.9 0.0 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase Shikimate_DH PF01488.20 KXS21793.1 - 0.057 13.5 0.0 0.47 10.5 0.0 2.3 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Ribosomal_L2_C PF03947.18 KXS21794.1 - 2.8e-45 153.6 4.0 4.2e-45 153.0 4.0 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 KXS21794.1 - 1.4e-13 50.5 0.2 4e-13 49.1 0.2 1.8 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain DUF3712 PF12505.8 KXS21795.1 - 5.4e-08 33.1 4.9 5.8e-05 23.3 0.1 3.6 3 1 0 3 3 3 2 Protein of unknown function (DUF3712) LEA_2 PF03168.13 KXS21795.1 - 0.015 15.8 0.7 13 6.4 0.0 4.6 5 0 0 5 5 5 0 Late embryogenesis abundant protein Cytochrom_B561 PF03188.16 KXS21796.1 - 0.0028 17.8 6.5 0.0043 17.2 6.5 1.3 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF202 PF02656.15 KXS21796.1 - 5.1 7.6 14.0 95 3.6 5.7 4.0 2 1 1 3 3 3 0 Domain of unknown function (DUF202) Fasciclin PF02469.22 KXS21798.1 - 4.1e-24 85.2 0.4 1.1e-07 32.1 0.0 4.8 4 1 0 4 4 4 4 Fasciclin domain Methyltransf_11 PF08241.12 KXS21799.1 - 2.1e-20 73.1 0.0 4.3e-20 72.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXS21799.1 - 3.4e-18 66.1 0.0 6.4e-18 65.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXS21799.1 - 2.6e-11 44.1 0.0 4.9e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXS21799.1 - 8.5e-11 41.9 0.0 1.2e-10 41.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXS21799.1 - 4.7e-10 39.5 0.0 6.4e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXS21799.1 - 6.4e-07 28.9 0.0 8.7e-07 28.5 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.15 KXS21799.1 - 1.3e-05 25.1 0.0 2.1e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Hypothetical methyltransferase MTS PF05175.14 KXS21799.1 - 0.001 18.6 0.0 0.0082 15.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase small domain DREV PF05219.12 KXS21799.1 - 0.02 14.0 0.0 0.028 13.5 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_22 PF13383.6 KXS21799.1 - 0.22 11.1 0.0 0.36 10.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PPR_2 PF13041.6 KXS21800.1 - 1.2e-10 41.5 0.0 5.2e-05 23.4 0.0 5.2 4 2 1 5 5 5 2 PPR repeat family PPR_3 PF13812.6 KXS21800.1 - 1.5e-10 41.0 0.0 0.0022 18.0 0.0 4.4 3 2 2 5 5 5 3 Pentatricopeptide repeat domain PPR_long PF17177.4 KXS21800.1 - 2e-09 37.1 0.0 0.0013 18.1 0.0 3.0 2 0 0 2 2 2 2 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 KXS21800.1 - 2.5e-06 27.3 4.2 9.8 6.7 0.0 8.2 9 0 0 9 9 9 1 PPR repeat DUF4132 PF13569.6 KXS21800.1 - 0.02 14.7 3.1 0.25 11.1 0.2 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4132) TPR_19 PF14559.6 KXS21800.1 - 2.1 8.9 7.8 6.6 7.3 0.1 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF4687 PF15747.5 KXS21800.1 - 4.6 7.7 10.5 2.3 8.7 0.9 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4687) PTH2 PF01981.16 KXS21801.1 - 9.4e-18 64.6 0.0 2.2e-17 63.4 0.0 1.5 1 1 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 MFS_1 PF07690.16 KXS21802.1 - 5.9e-41 140.6 73.2 3.4e-34 118.3 39.8 3.1 1 1 2 3 3 3 2 Major Facilitator Superfamily AAA PF00004.29 KXS21803.1 - 1.9e-38 131.9 0.0 4.8e-15 56.2 0.0 3.7 3 0 0 3 3 3 3 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KXS21803.1 - 5e-16 59.2 6.7 0.074 13.3 0.0 7.0 4 3 1 5 5 5 4 AAA domain AAA_lid_6 PF17866.1 KXS21803.1 - 2.1e-14 53.5 10.0 3.5e-05 23.9 0.1 4.9 4 1 1 5 5 4 3 AAA lid domain Mg_chelatase PF01078.21 KXS21803.1 - 7.2e-13 48.4 1.3 0.023 14.1 0.0 5.5 3 3 2 5 5 5 3 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KXS21803.1 - 2.4e-11 43.8 0.3 0.008 16.2 0.1 4.0 3 0 0 3 3 3 3 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 KXS21803.1 - 2.8e-11 43.5 0.9 0.0018 18.0 0.0 3.8 3 1 0 3 3 3 3 AAA domain RuvB_N PF05496.12 KXS21803.1 - 1.3e-10 41.2 0.1 0.00087 19.1 0.0 3.9 3 1 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activat PF00158.26 KXS21803.1 - 7.4e-09 35.5 2.4 3.3 7.4 0.2 5.4 3 2 1 4 4 4 0 Sigma-54 interaction domain RNA_helicase PF00910.22 KXS21803.1 - 7.7e-09 35.9 0.1 0.011 16.2 0.0 3.7 3 0 0 3 3 3 2 RNA helicase AAA_33 PF13671.6 KXS21803.1 - 1.4e-08 35.0 0.5 0.062 13.5 0.0 4.0 3 0 0 3 3 3 3 AAA domain Viral_helicase1 PF01443.18 KXS21803.1 - 5.5e-08 32.8 0.2 0.026 14.2 0.0 3.4 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase Sigma54_activ_2 PF14532.6 KXS21803.1 - 9.4e-08 32.3 0.1 0.027 14.6 0.0 3.9 3 1 0 3 3 3 1 Sigma-54 interaction domain AAA_16 PF13191.6 KXS21803.1 - 1e-07 32.5 6.0 0.015 15.7 0.2 4.6 4 1 0 4 4 3 2 AAA ATPase domain AAA_19 PF13245.6 KXS21803.1 - 1.2e-06 28.9 6.5 0.14 12.5 0.1 4.8 3 3 1 4 4 4 2 AAA domain NTPase_1 PF03266.15 KXS21803.1 - 1.4e-06 28.4 3.7 0.044 13.7 0.0 4.0 4 0 0 4 4 3 2 NTPase Torsin PF06309.11 KXS21803.1 - 1.9e-06 28.0 0.1 0.021 14.9 0.0 3.6 3 0 0 3 3 3 2 Torsin AAA_18 PF13238.6 KXS21803.1 - 2.1e-06 28.3 10.4 0.18 12.4 0.0 4.5 4 0 0 4 4 3 3 AAA domain IstB_IS21 PF01695.17 KXS21803.1 - 4e-06 26.7 0.1 1.2 8.8 0.0 4.0 4 0 0 4 4 4 2 IstB-like ATP binding protein AAA_2 PF07724.14 KXS21803.1 - 1.2e-05 25.5 1.5 0.14 12.3 0.0 3.9 4 0 0 4 4 3 2 AAA domain (Cdc48 subfamily) AAA_24 PF13479.6 KXS21803.1 - 4.6e-05 23.2 0.3 4.1 7.1 0.0 3.6 3 0 0 3 3 3 0 AAA domain AAA_28 PF13521.6 KXS21803.1 - 6.4e-05 23.3 5.6 1.2 9.4 0.0 4.4 4 0 0 4 4 3 2 AAA domain DUF3987 PF13148.6 KXS21803.1 - 0.00019 20.6 4.3 0.45 9.5 0.0 4.0 4 0 0 4 4 3 2 Protein of unknown function (DUF3987) AAA_7 PF12775.7 KXS21803.1 - 0.00022 20.8 0.4 7.7 6.0 0.0 3.8 3 0 0 3 3 3 0 P-loop containing dynein motor region AAA_3 PF07726.11 KXS21803.1 - 0.00025 20.9 0.0 0.99 9.3 0.0 3.4 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) KTI12 PF08433.10 KXS21803.1 - 0.0003 20.3 0.1 0.26 10.7 0.0 3.4 3 0 0 3 3 3 1 Chromatin associated protein KTI12 PRK PF00485.18 KXS21803.1 - 0.00031 20.6 0.3 0.37 10.5 0.0 2.8 3 0 0 3 3 2 1 Phosphoribulokinase / Uridine kinase family APS_kinase PF01583.20 KXS21803.1 - 0.00068 19.6 0.1 0.23 11.4 0.0 3.1 3 0 0 3 3 3 1 Adenylylsulphate kinase NACHT PF05729.12 KXS21803.1 - 0.001 19.0 0.2 1.2 9.1 0.0 3.7 3 0 0 3 3 3 1 NACHT domain TsaE PF02367.17 KXS21803.1 - 0.0011 18.9 0.2 4.2 7.4 0.0 3.5 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 KXS21803.1 - 0.0012 18.2 3.8 1.4 8.2 0.0 4.8 5 0 0 5 5 5 1 Zeta toxin DUF2075 PF09848.9 KXS21803.1 - 0.0021 17.4 7.4 6 6.0 0.1 5.6 3 3 2 5 5 5 0 Uncharacterized conserved protein (DUF2075) SKI PF01202.22 KXS21803.1 - 0.0036 17.4 0.4 2.8 8.0 0.0 3.5 3 0 0 3 3 3 1 Shikimate kinase AAA_29 PF13555.6 KXS21803.1 - 0.0044 16.7 0.0 2.8 7.8 0.0 3.4 3 0 0 3 3 3 1 P-loop containing region of AAA domain Thymidylate_kin PF02223.17 KXS21803.1 - 0.0068 16.1 6.8 7 6.3 0.0 4.3 4 0 0 4 4 4 0 Thymidylate kinase DNA_pol3_delta2 PF13177.6 KXS21803.1 - 0.0073 16.1 0.0 0.88 9.3 0.0 3.4 3 0 0 3 3 3 1 DNA polymerase III, delta subunit TrwB_AAD_bind PF10412.9 KXS21803.1 - 0.0076 15.2 1.6 1.5 7.7 0.1 3.3 3 0 0 3 3 3 1 Type IV secretion-system coupling protein DNA-binding domain AAA_11 PF13086.6 KXS21803.1 - 0.0093 15.8 11.2 4.3 7.0 0.0 4.5 4 1 0 4 4 4 0 AAA domain tRNA_lig_kinase PF08303.11 KXS21803.1 - 0.016 15.3 0.3 0.66 10.0 0.0 3.3 4 0 0 4 4 3 0 tRNA ligase kinase domain PhoH PF02562.16 KXS21803.1 - 0.022 14.2 1.4 7.1 6.0 0.1 4.2 4 0 0 4 4 4 0 PhoH-like protein CbiA PF01656.23 KXS21803.1 - 0.025 14.6 1.5 6.4 6.9 0.1 3.4 3 1 0 3 3 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain MeaB PF03308.16 KXS21803.1 - 0.027 13.5 0.8 0.88 8.5 0.0 3.0 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ATPase PF06745.13 KXS21803.1 - 0.034 13.5 0.6 19 4.5 0.0 3.5 3 0 0 3 3 3 0 KaiC T2SSE PF00437.20 KXS21803.1 - 0.035 13.2 0.1 2.6 7.0 0.0 2.9 3 0 0 3 3 3 0 Type II/IV secretion system protein AAA_25 PF13481.6 KXS21803.1 - 0.036 13.6 0.3 26 4.3 0.0 3.7 3 0 0 3 3 3 0 AAA domain Zot PF05707.12 KXS21803.1 - 0.039 13.6 2.4 42 3.7 0.1 5.0 3 2 1 4 4 4 0 Zonular occludens toxin (Zot) MobB PF03205.14 KXS21803.1 - 0.042 13.8 0.5 5.7 6.8 0.0 3.7 4 0 0 4 4 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.6 KXS21803.1 - 0.042 14.3 17.2 0.18 12.3 0.1 4.7 5 0 0 5 5 3 0 AAA domain Rad17 PF03215.15 KXS21803.1 - 0.044 13.7 0.1 5.2 6.9 0.0 3.2 3 0 0 3 3 3 0 Rad17 P-loop domain CoaE PF01121.20 KXS21803.1 - 0.048 13.3 0.2 5.7 6.6 0.0 3.4 3 0 0 3 3 3 0 Dephospho-CoA kinase SRP54 PF00448.22 KXS21803.1 - 0.066 12.8 2.8 21 4.7 0.0 3.4 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain ABC_tran PF00005.27 KXS21803.1 - 0.068 13.7 7.8 2.8 8.5 0.0 4.1 4 0 0 4 4 3 0 ABC transporter DAP3 PF10236.9 KXS21803.1 - 0.094 11.9 0.1 2.1 7.5 0.0 2.7 3 0 0 3 3 2 0 Mitochondrial ribosomal death-associated protein 3 G-alpha PF00503.20 KXS21803.1 - 0.097 11.8 0.6 0.24 10.5 0.0 2.0 3 0 0 3 3 2 0 G-protein alpha subunit FtsK_SpoIIIE PF01580.18 KXS21803.1 - 0.11 11.9 0.0 20 4.5 0.0 3.2 3 0 0 3 3 3 0 FtsK/SpoIIIE family Mur_ligase_M PF08245.12 KXS21803.1 - 0.14 12.1 2.9 25 4.8 0.0 3.4 3 0 0 3 3 3 0 Mur ligase middle domain ATP_bind_1 PF03029.17 KXS21803.1 - 0.15 11.8 1.1 4.3 7.1 0.1 3.2 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein cobW PF02492.19 KXS21803.1 - 0.39 10.3 1.9 8.6 5.9 0.0 3.0 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_13 PF13166.6 KXS21803.1 - 2.3 6.8 12.3 0.55 8.8 0.0 3.3 4 0 0 4 4 4 0 AAA domain MCM3AP_GANP PF16769.5 KXS21803.1 - 6.3 4.9 7.3 12 4.0 7.3 1.3 1 0 0 1 1 1 0 MCM3AP domain of GANP AAA_11 PF13086.6 KXS21804.1 - 6.1e-20 72.1 0.1 7.3e-09 35.8 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KXS21804.1 - 0.01 15.6 0.0 0.9 9.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_12 PF13087.6 KXS21804.1 - 0.019 14.6 0.0 0.033 13.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain SART-1 PF03343.13 KXS21804.1 - 0.048 12.2 1.6 0.079 11.5 1.6 1.2 1 0 0 1 1 1 0 SART-1 family AAA_19 PF13245.6 KXS21804.1 - 0.086 13.2 0.1 1.7 9.0 0.0 2.8 3 0 0 3 3 3 0 AAA domain UIM PF02809.20 KXS21804.1 - 9.4 6.4 7.3 0.57 10.2 1.4 2.2 2 0 0 2 2 2 0 Ubiquitin interaction motif TPR_1 PF00515.28 KXS21805.1 - 3.9e-08 32.8 0.0 0.0035 17.1 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KXS21805.1 - 9.2e-05 22.3 0.9 2.2 8.6 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 KXS21805.1 - 0.00044 20.5 10.1 0.35 11.2 0.2 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 KXS21805.1 - 0.00078 19.3 1.3 1.8 8.8 0.1 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 KXS21805.1 - 0.0087 16.2 0.0 0.71 10.2 0.0 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 KXS21805.1 - 0.031 14.2 12.4 0.14 12.1 0.0 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat GDP_Man_Dehyd PF16363.5 KXS21806.1 - 3.7e-54 184.4 0.0 4.2e-54 184.2 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KXS21806.1 - 2.9e-48 164.5 0.0 3.9e-48 164.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXS21806.1 - 7.9e-18 64.4 0.0 9.3e-17 60.9 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KXS21806.1 - 1.6e-16 60.3 0.0 1.3e-15 57.3 0.0 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KXS21806.1 - 1.9e-12 46.9 0.0 2.8e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 KXS21806.1 - 8.6e-08 31.7 0.1 2.6e-06 26.8 0.1 2.2 1 1 0 1 1 1 1 Male sterility protein KR PF08659.10 KXS21806.1 - 1.8e-05 24.7 0.0 3.2e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 KXS21806.1 - 0.00028 20.4 0.0 0.00059 19.3 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.6 KXS21806.1 - 0.00036 20.5 0.0 0.00085 19.3 0.0 1.6 1 0 0 1 1 1 1 NAD(P)H-binding Isochorismatase PF00857.20 KXS21806.1 - 0.0087 16.3 0.0 0.43 10.7 0.0 2.8 2 1 1 3 3 3 1 Isochorismatase family UDPG_MGDP_dh_N PF03721.14 KXS21806.1 - 0.028 14.0 0.1 0.08 12.5 0.0 1.7 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Asparaginase_C PF17763.1 KXS21806.1 - 0.19 12.0 0.2 0.57 10.4 0.0 1.8 2 0 0 2 2 2 0 Glutaminase/Asparaginase C-terminal domain TPR_2 PF07719.17 KXS21807.1 - 2.8e-16 58.2 5.1 0.0018 18.3 0.0 6.6 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_1 PF00515.28 KXS21807.1 - 2.4e-15 55.6 1.4 0.0017 18.1 0.0 5.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 KXS21807.1 - 9.5e-15 54.9 8.4 0.00013 22.4 0.3 5.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 KXS21807.1 - 4.2e-14 52.0 0.8 0.0037 16.9 0.0 5.5 6 0 0 6 6 5 4 TPR repeat TPR_8 PF13181.6 KXS21807.1 - 8.4e-13 47.4 0.2 0.11 12.8 0.0 5.8 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 KXS21807.1 - 1.1e-12 47.6 9.0 0.038 14.8 0.1 7.6 5 2 2 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.6 KXS21807.1 - 1.1e-11 45.2 10.0 0.03 15.0 0.1 6.3 5 1 0 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 KXS21807.1 - 7.5e-10 38.1 0.8 1.4 9.2 0.0 5.6 5 0 0 5 5 5 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KXS21807.1 - 7.6e-09 35.7 0.1 0.45 10.8 0.0 5.4 4 1 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 KXS21807.1 - 3.1e-07 30.6 14.5 0.14 12.4 0.0 6.1 6 1 0 6 6 6 3 Tetratricopeptide repeat TPR_21 PF09976.9 KXS21807.1 - 2.7e-05 24.0 1.8 0.28 10.9 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat-like domain TPR_MalT PF17874.1 KXS21807.1 - 0.00054 19.4 1.4 1.2 8.4 0.0 4.0 3 1 1 4 4 4 1 MalT-like TPR region TPR_9 PF13371.6 KXS21807.1 - 0.001 19.2 8.6 0.91 9.7 0.0 5.0 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 KXS21807.1 - 0.0014 19.1 1.6 70 4.4 0.1 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.6 KXS21807.1 - 0.0018 18.5 0.1 0.046 14.1 0.0 3.6 5 0 0 5 5 2 1 Tetratricopeptide repeat TPR_15 PF13429.6 KXS21807.1 - 0.0066 15.7 6.2 0.047 12.9 0.0 4.2 4 1 2 6 6 6 1 Tetratricopeptide repeat TPR_20 PF14561.6 KXS21807.1 - 0.11 12.9 0.3 0.71 10.2 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat BTAD PF03704.17 KXS21807.1 - 2 8.8 7.0 44 4.5 0.2 4.3 3 1 0 4 4 4 0 Bacterial transcriptional activator domain AFG1_ATPase PF03969.16 KXS21808.1 - 2.7e-68 230.5 0.0 4.3e-65 220.0 0.0 2.6 2 1 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.6 KXS21808.1 - 8.7e-06 26.2 0.7 0.0012 19.3 0.7 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KXS21808.1 - 0.0039 17.5 0.1 0.021 15.1 0.1 2.3 2 1 0 2 2 2 1 AAA domain Bac_DnaA PF00308.18 KXS21808.1 - 0.016 15.1 0.1 0.084 12.7 0.1 2.0 1 1 0 1 1 1 0 Bacterial dnaA protein AAA PF00004.29 KXS21808.1 - 0.03 14.7 0.1 0.17 12.3 0.0 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KXS21808.1 - 0.065 13.2 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 KXS21808.1 - 0.17 12.3 0.0 0.43 11.0 0.0 1.7 2 0 0 2 2 2 0 RNA helicase DUF883 PF05957.13 KXS21809.1 - 0.0031 18.1 1.6 0.0031 18.1 1.6 8.1 2 1 7 9 9 9 4 Bacterial protein of unknown function (DUF883) F-box PF00646.33 KXS21810.1 - 0.0033 17.3 2.2 0.011 15.6 2.2 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KXS21810.1 - 0.0071 16.2 0.7 0.038 13.9 0.9 2.1 2 0 0 2 2 2 1 F-box-like TPR_12 PF13424.6 KXS21811.1 - 1.9e-07 31.3 2.4 0.34 11.2 0.2 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 KXS21811.1 - 0.00027 20.7 0.0 0.13 12.1 0.0 3.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 KXS21811.1 - 0.052 13.4 0.0 9.1 6.3 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 KXS21811.1 - 0.1 12.7 0.1 5.7 7.2 0.0 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Dioxygenase_C PF00775.21 KXS21812.1 - 3.1e-08 33.3 0.5 7.2e-08 32.1 0.5 1.6 1 1 0 1 1 1 1 Dioxygenase zf-C3HC4_3 PF13920.6 KXS21813.1 - 1.2e-15 57.1 7.6 1.8e-15 56.5 7.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KXS21813.1 - 2.2e-07 30.6 6.8 3.8e-07 29.8 6.8 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KXS21813.1 - 2.4e-05 24.6 6.9 4e-05 23.9 6.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KXS21813.1 - 4.6e-05 23.2 6.7 9.2e-05 22.2 6.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXS21813.1 - 0.0048 16.8 6.5 0.0079 16.1 6.5 1.3 1 0 0 1 1 1 1 zinc-RING finger domain Ank PF00023.30 KXS21813.1 - 0.011 16.2 0.0 0.047 14.2 0.0 2.1 2 0 0 2 2 2 0 Ankyrin repeat zf-C3HC4_2 PF13923.6 KXS21813.1 - 0.016 15.0 8.1 0.04 13.8 7.9 1.8 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Ank_3 PF13606.6 KXS21813.1 - 0.027 15.0 0.0 0.32 11.7 0.0 2.9 3 0 0 3 3 3 0 Ankyrin repeat zf-RING_4 PF14570.6 KXS21813.1 - 0.095 12.5 5.4 0.19 11.6 5.4 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain CCP_MauG PF03150.14 KXS21813.1 - 0.12 13.0 0.0 0.22 12.1 0.0 1.4 1 0 0 1 1 1 0 Di-haem cytochrome c peroxidase Thiolase_N PF00108.23 KXS21815.1 - 2.2e-75 253.4 1.1 1.2e-74 250.9 0.2 1.9 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KXS21815.1 - 6e-48 161.6 0.4 1.5e-47 160.3 0.4 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain DUF4473 PF14747.6 KXS21815.1 - 0.1 13.2 0.8 0.42 11.2 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4473) ketoacyl-synt PF00109.26 KXS21815.1 - 0.37 10.3 5.1 0.3 10.6 0.3 2.8 4 0 0 4 4 4 0 Beta-ketoacyl synthase, N-terminal domain DUF1839 PF08893.10 KXS21816.1 - 0.14 11.3 0.0 0.27 10.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1839) AAA PF00004.29 KXS21818.1 - 1.1e-12 48.5 0.0 2.2e-12 47.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KXS21818.1 - 2e-06 27.8 0.0 4.2e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KXS21818.1 - 3.8e-06 27.2 0.0 1.2e-05 25.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 KXS21818.1 - 6.9e-06 26.1 0.1 0.00027 20.9 0.0 2.2 2 0 0 2 2 2 1 Rad17 P-loop domain RuvB_N PF05496.12 KXS21818.1 - 2.8e-05 23.9 0.0 5.5e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 KXS21818.1 - 4e-05 23.8 0.0 8.7e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KXS21818.1 - 0.00028 21.3 0.0 0.0012 19.2 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 KXS21818.1 - 0.0039 17.7 0.0 0.0081 16.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KXS21818.1 - 0.0088 15.8 0.0 0.0088 15.8 0.0 2.3 3 0 0 3 3 3 1 AAA domain AAA_14 PF13173.6 KXS21818.1 - 0.0094 16.0 0.0 0.016 15.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 KXS21818.1 - 0.013 15.6 0.0 0.027 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_25 PF13481.6 KXS21818.1 - 0.033 13.8 0.1 0.15 11.6 0.0 2.1 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KXS21818.1 - 0.036 13.2 0.0 0.075 12.2 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_28 PF13521.6 KXS21818.1 - 0.04 14.2 0.0 0.13 12.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KXS21818.1 - 0.048 13.7 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NTPase_1 PF03266.15 KXS21818.1 - 0.048 13.6 0.0 0.14 12.0 0.0 1.8 2 0 0 2 2 2 0 NTPase AAA_17 PF13207.6 KXS21818.1 - 0.089 13.2 0.0 0.2 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KXS21818.1 - 0.12 11.9 0.0 0.76 9.3 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region Homeodomain PF00046.29 KXS21819.1 - 2.7e-09 36.7 0.9 5.3e-09 35.8 0.9 1.5 1 0 0 1 1 1 1 Homeodomain Spc7 PF08317.11 KXS21820.1 - 0.0068 15.3 16.4 0.008 15.1 16.4 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein Flg_hook PF02120.16 KXS21820.1 - 0.031 14.1 6.1 0.086 12.7 0.4 2.7 1 1 2 3 3 3 0 Flagellar hook-length control protein FliK JIP_LZII PF16471.5 KXS21820.1 - 0.044 14.0 17.6 0.13 12.5 2.3 3.1 1 1 2 3 3 3 0 JNK-interacting protein leucine zipper II WD40_alt PF14077.6 KXS21820.1 - 0.056 13.3 6.4 1.7 8.5 0.1 3.5 2 1 1 3 3 3 0 Alternative WD40 repeat motif Prominin PF05478.11 KXS21820.1 - 0.12 10.4 3.8 0.14 10.1 3.8 1.1 1 0 0 1 1 1 0 Prominin DUF1664 PF07889.12 KXS21820.1 - 0.12 12.4 6.9 0.61 10.1 1.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Bacillus_HBL PF05791.11 KXS21820.1 - 0.16 11.8 3.2 0.2 11.5 2.0 1.6 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Laminin_II PF06009.12 KXS21820.1 - 0.23 11.5 9.1 0.25 11.3 7.6 1.8 1 1 1 2 2 2 0 Laminin Domain II USP8_interact PF08941.10 KXS21820.1 - 0.33 10.7 4.6 1.7 8.4 4.6 1.9 1 1 0 1 1 1 0 USP8 interacting Tho2 PF11262.8 KXS21820.1 - 0.68 9.1 7.1 0.8 8.8 7.1 1.3 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Med9 PF07544.13 KXS21820.1 - 1.4 9.0 12.9 6.2 7.0 1.6 3.3 1 1 2 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Uso1_p115_C PF04871.13 KXS21820.1 - 3 8.2 21.4 9 6.7 20.2 2.2 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region V_ATPase_I PF01496.19 KXS21820.1 - 4.8 5.0 9.6 5.3 4.8 9.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Exonuc_VII_L PF02601.15 KXS21820.1 - 6.7 6.2 11.3 8.2 5.9 11.3 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit ApoO PF09769.9 KXS21820.1 - 9.2 6.2 6.2 26 4.8 0.1 3.0 1 1 2 3 3 3 0 Apolipoprotein O DUF3450 PF11932.8 KXS21820.1 - 9.7 5.4 17.2 10 5.4 9.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Glyco_hydro_26 PF02156.15 KXS21821.1 - 5.1e-08 32.7 6.9 8.1e-07 28.8 0.1 2.2 1 1 1 2 2 2 2 Glycosyl hydrolase family 26 Glyco_hydro_26 PF02156.15 KXS21822.1 - 5.7e-06 26.0 7.2 0.0005 19.6 7.3 2.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 26 DUF3592 PF12158.8 KXS21822.1 - 0.088 12.9 1.7 0.18 11.9 1.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3592) Alpha_GJ PF03229.13 KXS21822.1 - 0.85 10.2 13.5 1.5 9.4 13.5 1.3 1 0 0 1 1 1 0 Alphavirus glycoprotein J Zn_clus PF00172.18 KXS21823.1 - 1.2e-07 31.7 15.3 2.2e-07 30.9 15.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Metal_resist PF13801.6 KXS21823.1 - 4.8 7.4 7.7 2.6 8.2 0.5 3.1 2 0 0 2 2 2 0 Heavy-metal resistance SH3_1 PF00018.28 KXS21824.1 - 5.5e-07 29.1 0.0 1.6e-06 27.6 0.0 1.8 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 KXS21824.1 - 6.4e-07 29.1 0.0 1.4e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KXS21824.1 - 0.00041 20.0 0.0 0.0008 19.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Syndecan PF01034.20 KXS21824.1 - 0.47 10.4 1.1 0.79 9.7 1.1 1.3 1 0 0 1 1 1 0 Syndecan domain SH3_9 PF14604.6 KXS21825.1 - 3.7e-06 26.7 0.0 7e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXS21825.1 - 3.6e-05 23.3 0.0 6.5e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 SH3 domain Ank_3 PF13606.6 KXS21825.1 - 0.00017 21.8 0.0 0.22 12.2 0.0 3.7 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.7 KXS21825.1 - 0.0016 19.0 0.0 0.057 14.0 0.0 2.8 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXS21825.1 - 0.0016 18.7 0.0 0.29 11.5 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXS21825.1 - 0.017 15.7 0.0 6.4 7.5 0.0 3.3 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Ank PF00023.30 KXS21825.1 - 0.071 13.6 0.0 13 6.4 0.0 3.4 3 0 0 3 3 3 0 Ankyrin repeat bZIP_2 PF07716.15 KXS21826.1 - 2.3e-11 43.6 10.7 4.1e-11 42.8 10.7 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 KXS21826.1 - 1.9e-06 27.9 11.8 3.5e-06 27.0 11.8 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 KXS21826.1 - 0.0023 18.4 9.6 0.0046 17.5 9.6 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor WD40_alt PF14077.6 KXS21826.1 - 2.4 8.1 3.5 57 3.7 0.1 3.0 2 1 1 3 3 3 0 Alternative WD40 repeat motif CASP_C PF08172.12 KXS21826.1 - 4.5 6.6 8.6 9.9 5.4 8.6 1.6 1 1 0 1 1 1 0 CASP C terminal IF-2B PF01008.17 KXS21827.1 - 3e-20 72.6 0.0 4.4e-20 72.1 0.0 1.2 1 0 0 1 1 1 1 Initiation factor 2 subunit family NUDIX PF00293.28 KXS21827.1 - 1.6e-07 31.4 0.0 3.1e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain CAP59_mtransfer PF11735.8 KXS21828.1 - 4.6e-74 249.1 0.0 5.8e-74 248.8 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 ABC_tran PF00005.27 KXS21829.1 - 6.3e-46 156.3 0.0 4.4e-22 79.1 0.0 2.8 3 0 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 KXS21829.1 - 5.6e-22 77.6 9.1 5.6e-22 77.6 9.1 2.4 3 0 0 3 3 1 1 ABC transporter AAA_21 PF13304.6 KXS21829.1 - 1.7e-18 67.5 0.2 0.0012 18.7 0.0 4.2 3 1 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KXS21829.1 - 9.4e-10 39.3 0.6 0.0043 17.6 0.0 3.5 3 0 0 3 3 3 2 AAA domain SMC_N PF02463.19 KXS21829.1 - 4.5e-09 36.1 1.4 0.014 14.9 0.0 4.5 3 2 0 4 4 3 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 KXS21829.1 - 9.9e-09 35.4 0.0 0.019 14.7 0.0 3.7 3 1 1 4 4 4 2 AAA ATPase domain Dynamin_N PF00350.23 KXS21829.1 - 1.3e-08 35.1 0.3 0.046 13.8 0.0 3.9 3 1 0 3 3 3 2 Dynamin family AAA_29 PF13555.6 KXS21829.1 - 1.6e-08 34.1 0.0 0.0074 16.0 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KXS21829.1 - 7.1e-07 29.3 0.1 0.0018 18.2 0.0 2.9 3 0 0 3 3 3 2 RsgA GTPase AAA_18 PF13238.6 KXS21829.1 - 7.6e-07 29.7 0.0 0.049 14.2 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_33 PF13671.6 KXS21829.1 - 1.7e-06 28.3 0.0 0.02 15.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_27 PF13514.6 KXS21829.1 - 2.2e-06 27.4 1.0 0.016 14.8 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_28 PF13521.6 KXS21829.1 - 2.4e-06 27.9 0.0 0.024 14.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KXS21829.1 - 4.9e-06 27.0 0.0 0.0073 16.7 0.0 2.9 2 1 0 2 2 2 1 AAA ATPase domain Rad17 PF03215.15 KXS21829.1 - 9.6e-06 25.6 0.0 0.05 13.5 0.0 2.9 3 0 0 3 3 2 2 Rad17 P-loop domain AAA PF00004.29 KXS21829.1 - 1.3e-05 25.6 0.0 0.45 10.9 0.1 3.3 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KXS21829.1 - 4.6e-05 23.8 1.2 2.1 8.8 0.0 3.6 3 0 0 3 3 3 2 RNA helicase AAA_24 PF13479.6 KXS21829.1 - 5e-05 23.1 0.0 0.22 11.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 KXS21829.1 - 6.6e-05 23.0 0.0 0.11 12.6 0.0 3.2 3 0 0 3 3 2 1 50S ribosome-binding GTPase NACHT PF05729.12 KXS21829.1 - 0.00012 22.0 0.0 0.14 12.0 0.0 2.5 2 0 0 2 2 2 2 NACHT domain AAA_5 PF07728.14 KXS21829.1 - 0.00016 21.7 0.1 1 9.4 0.0 3.3 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.12 KXS21829.1 - 0.00031 20.1 0.0 0.32 10.2 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin TsaE PF02367.17 KXS21829.1 - 0.00059 19.8 0.0 1.6 8.7 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 KXS21829.1 - 0.0011 19.3 0.0 1.9 8.8 0.0 2.9 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KXS21829.1 - 0.0014 18.4 0.0 0.15 11.8 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_14 PF13173.6 KXS21829.1 - 0.0018 18.3 0.0 2 8.4 0.0 3.3 4 0 0 4 4 2 1 AAA domain AAA_17 PF13207.6 KXS21829.1 - 0.0019 18.6 0.0 0.58 10.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 KXS21829.1 - 0.0026 17.0 0.1 0.076 12.2 0.0 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF815) MeaB PF03308.16 KXS21829.1 - 0.0044 16.0 0.0 2.2 7.2 0.0 2.6 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB VirE PF05272.11 KXS21829.1 - 0.0065 16.2 0.0 1.1 9.0 0.0 2.8 3 0 0 3 3 3 1 Virulence-associated protein E AAA_25 PF13481.6 KXS21829.1 - 0.0074 15.9 0.0 3.3 7.2 0.0 2.9 2 1 0 2 2 2 1 AAA domain Cytidylate_kin PF02224.18 KXS21829.1 - 0.021 14.5 0.0 0.53 10.0 0.0 2.4 2 0 0 2 2 2 0 Cytidylate kinase T2SSE PF00437.20 KXS21829.1 - 0.023 13.8 0.0 0.69 8.9 0.0 2.8 3 0 0 3 3 3 0 Type II/IV secretion system protein AAA_7 PF12775.7 KXS21829.1 - 0.026 14.0 0.2 1.8 8.0 0.0 2.7 3 0 0 3 3 3 0 P-loop containing dynein motor region Roc PF08477.13 KXS21829.1 - 0.032 14.5 0.0 5.1 7.4 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_30 PF13604.6 KXS21829.1 - 0.033 13.9 6.7 0.15 11.8 0.0 3.8 4 1 0 4 4 4 0 AAA domain RuvB_N PF05496.12 KXS21829.1 - 0.04 13.7 0.0 2.2 8.0 0.0 2.5 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain ATPase_2 PF01637.18 KXS21829.1 - 0.059 13.3 0.1 18 5.1 0.0 3.1 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea MarR_2 PF12802.7 KXS21829.1 - 0.062 13.2 0.0 1.4 8.8 0.0 2.6 2 0 0 2 2 2 0 MarR family PRK PF00485.18 KXS21829.1 - 0.067 12.9 0.0 6.4 6.5 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family NB-ARC PF00931.22 KXS21829.1 - 0.067 12.4 0.1 4.7 6.3 0.0 2.9 2 1 0 2 2 2 0 NB-ARC domain NTPase_1 PF03266.15 KXS21829.1 - 0.072 13.0 0.0 2.7 7.9 0.0 2.6 2 0 0 2 2 2 0 NTPase Jacalin PF01419.17 KXS21829.1 - 0.11 12.4 0.2 0.36 10.8 0.2 1.8 1 0 0 1 1 1 0 Jacalin-like lectin domain ATP_bind_1 PF03029.17 KXS21829.1 - 0.12 12.1 0.9 16 5.2 0.0 2.8 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein MutS_V PF00488.21 KXS21829.1 - 0.18 11.8 0.8 42 4.1 0.0 3.2 3 0 0 3 3 3 0 MutS domain V ABC2_membrane PF01061.24 KXS21830.1 - 2e-43 148.3 21.0 3e-43 147.7 21.0 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 KXS21830.1 - 1.9e-30 106.2 0.0 3.1e-30 105.5 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KXS21830.1 - 0.00014 21.7 1.2 0.14 12.0 0.0 2.3 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KXS21830.1 - 0.0014 18.6 0.1 0.0025 17.7 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_28 PF13521.6 KXS21830.1 - 0.0015 18.8 0.0 0.0027 18.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 KXS21830.1 - 0.0091 16.5 0.1 0.016 15.8 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KXS21830.1 - 0.0096 16.3 0.0 0.018 15.4 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 KXS21830.1 - 0.01 15.6 0.1 0.022 14.5 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KXS21830.1 - 0.014 15.4 0.4 0.034 14.2 0.4 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase IstB_IS21 PF01695.17 KXS21830.1 - 0.015 15.1 0.1 0.081 12.6 0.1 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein NTPase_1 PF03266.15 KXS21830.1 - 0.024 14.5 0.0 3 7.7 0.0 2.3 2 0 0 2 2 2 0 NTPase AAA_25 PF13481.6 KXS21830.1 - 0.026 14.1 0.0 0.069 12.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KXS21830.1 - 0.06 13.5 0.0 0.14 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 KXS21830.1 - 0.062 13.7 0.0 0.16 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain ABC_ATPase PF09818.9 KXS21830.1 - 0.067 12.0 0.2 0.15 10.9 0.2 1.4 1 0 0 1 1 1 0 Predicted ATPase of the ABC class T2SSE PF00437.20 KXS21830.1 - 0.07 12.2 0.1 0.13 11.3 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF2075 PF09848.9 KXS21830.1 - 0.077 12.2 0.1 1.5 8.0 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) ABC2_membrane_3 PF12698.7 KXS21830.1 - 0.15 11.2 27.2 0.35 9.9 27.3 1.5 1 1 0 1 1 1 0 ABC-2 family transporter protein Aa_trans PF01490.18 KXS21832.1 - 3.8e-52 177.4 29.1 4.8e-52 177.0 29.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein LCAT PF02450.15 KXS21833.1 - 4.3e-42 144.7 0.0 5.2e-36 124.7 0.0 2.6 2 1 0 2 2 2 2 Lecithin:cholesterol acyltransferase NT-C2 PF10358.9 KXS21833.1 - 0.0022 17.7 0.0 0.0079 15.9 0.0 1.9 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins Abhydrolase_6 PF12697.7 KXS21833.1 - 0.0024 18.5 0.3 0.0072 17.0 0.0 1.9 2 1 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXS21833.1 - 0.11 11.7 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 P35 PF02331.15 KXS21834.1 - 0.088 12.2 0.0 0.17 11.2 0.0 1.5 2 0 0 2 2 2 0 Apoptosis preventing protein DUF4253 PF14062.6 KXS21834.1 - 0.15 12.3 0.1 17 5.6 0.0 2.8 3 1 0 3 3 3 0 Domain of unknown function (DUF4253) CAMSAP_CC1 PF17095.5 KXS21835.1 - 0.12 12.3 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 Spectrin-binding region of Ca2+-Calmodulin Hamartin PF04388.12 KXS21835.1 - 4.6 5.8 8.1 5.4 5.5 8.1 1.1 1 0 0 1 1 1 0 Hamartin protein DEAD PF00270.29 KXS21836.1 - 3.1e-26 92.2 0.0 3.3e-25 88.8 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXS21836.1 - 2.9e-23 82.3 0.0 1.8e-19 70.2 0.0 2.8 2 0 0 2 2 2 2 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 KXS21836.1 - 1.5e-18 67.2 5.3 1.5e-18 67.2 5.3 1.7 2 0 0 2 2 2 1 RecQ zinc-binding ResIII PF04851.15 KXS21836.1 - 5.1e-09 36.4 0.0 9e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit NUDIX PF00293.28 KXS21837.1 - 2.3e-09 37.4 0.0 4.1e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain DUF3169 PF11368.8 KXS21838.1 - 0.18 11.3 0.0 0.18 11.3 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3169) Ank_3 PF13606.6 KXS21839.1 - 4.2e-06 26.7 0.0 0.00059 20.1 0.0 3.6 3 0 0 3 3 3 1 Ankyrin repeat SH3_9 PF14604.6 KXS21839.1 - 5.4e-06 26.2 0.0 1.2e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Ank_2 PF12796.7 KXS21839.1 - 3.8e-05 24.2 0.0 0.00049 20.6 0.0 2.7 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 KXS21839.1 - 5.3e-05 23.5 0.0 0.029 14.8 0.0 3.0 3 0 0 3 3 2 1 Ankyrin repeat Ank_4 PF13637.6 KXS21839.1 - 0.00011 22.7 0.0 0.0014 19.2 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) SH3_1 PF00018.28 KXS21839.1 - 0.00026 20.6 0.0 0.00056 19.5 0.0 1.6 1 0 0 1 1 1 1 SH3 domain Ank_5 PF13857.6 KXS21839.1 - 0.0014 18.9 0.0 0.005 17.1 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) DASH_Dam1 PF08653.10 KXS21839.1 - 0.056 13.2 4.5 3.1 7.7 0.2 3.6 3 0 0 3 3 3 0 DASH complex subunit Dam1 LPP PF04728.13 KXS21839.1 - 0.071 13.5 8.0 0.22 11.9 0.7 3.5 3 0 0 3 3 3 0 Lipoprotein leucine-zipper SlyX PF04102.12 KXS21839.1 - 0.18 12.4 20.6 11 6.7 0.3 5.6 5 1 1 6 6 5 0 SlyX DUF948 PF06103.11 KXS21839.1 - 0.19 12.0 8.5 2.6 8.4 0.1 4.4 4 2 2 6 6 6 0 Bacterial protein of unknown function (DUF948) DUF4507 PF14964.6 KXS21839.1 - 0.24 10.3 2.0 0.42 9.5 2.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4507) DUF16 PF01519.16 KXS21839.1 - 0.27 11.7 8.1 23 5.5 2.0 3.8 3 1 1 4 4 4 0 Protein of unknown function DUF16 Cohesin_load PF10345.9 KXS21839.1 - 0.28 9.6 3.3 0.24 9.8 1.0 1.9 2 1 1 3 3 3 0 Cohesin loading factor MbeD_MobD PF04899.12 KXS21839.1 - 0.4 10.8 3.3 10 6.3 0.1 3.5 3 0 0 3 3 3 0 MbeD/MobD like KASH_CCD PF14662.6 KXS21839.1 - 0.52 10.1 9.3 0.7 9.7 1.9 3.0 2 1 1 3 3 3 0 Coiled-coil region of CCDC155 or KASH Seryl_tRNA_N PF02403.22 KXS21839.1 - 0.7 10.1 6.3 0.7 10.1 0.1 3.2 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain NPV_P10 PF05531.12 KXS21839.1 - 0.71 10.4 14.2 0.43 11.1 0.5 4.6 4 1 1 5 5 5 0 Nucleopolyhedrovirus P10 protein BLOC1_2 PF10046.9 KXS21839.1 - 0.83 10.0 9.2 15 6.0 0.3 4.0 4 0 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spc7 PF08317.11 KXS21839.1 - 0.98 8.2 15.6 0.18 10.7 7.7 2.4 2 1 0 2 2 2 0 Spc7 kinetochore protein Fib_alpha PF08702.10 KXS21839.1 - 2 8.6 10.4 1 9.5 1.2 3.6 2 2 1 4 4 4 0 Fibrinogen alpha/beta chain family DUF3584 PF12128.8 KXS21839.1 - 4.7 4.6 19.4 0.16 9.5 6.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Baculo_PEP_C PF04513.12 KXS21839.1 - 5.8 7.0 16.3 1.9 8.6 0.2 4.4 3 2 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Methyltransf_16 PF10294.9 KXS21840.1 - 3.5e-06 26.9 0.0 0.0011 18.8 0.0 2.3 2 0 0 2 2 2 2 Lysine methyltransferase PrmA PF06325.13 KXS21840.1 - 0.019 14.4 0.5 0.083 12.3 0.0 2.0 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.12 KXS21840.1 - 0.035 14.8 0.0 0.06 14.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 KXS21840.1 - 0.046 13.3 0.2 0.76 9.3 0.2 2.2 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_28 PF02636.17 KXS21840.1 - 0.1 12.2 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_25 PF13649.6 KXS21840.1 - 0.14 12.9 0.1 0.49 11.1 0.1 1.9 1 1 0 1 1 1 0 Methyltransferase domain adh_short_C2 PF13561.6 KXS21841.1 - 3.1e-53 180.8 0.5 4.1e-53 180.4 0.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXS21841.1 - 7.8e-40 136.4 0.1 9.7e-40 136.1 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXS21841.1 - 2.3e-08 34.2 0.1 3.6e-08 33.5 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXS21841.1 - 5.8e-05 22.7 0.2 0.00018 21.0 0.2 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 KXS21841.1 - 7.8e-05 22.0 0.1 0.0003 20.1 0.0 1.9 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_10 PF13460.6 KXS21841.1 - 0.00042 20.3 1.1 0.00083 19.3 1.1 1.5 1 1 0 1 1 1 1 NAD(P)H-binding ApbA PF02558.16 KXS21841.1 - 0.066 12.8 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 KXS21841.1 - 0.081 12.8 0.1 0.17 11.8 0.0 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MINDY_DUB PF04424.13 KXS21843.1 - 2.1e-27 95.5 0.0 4.6e-27 94.4 0.0 1.6 1 0 0 1 1 1 1 MINDY deubiquitinase NAD_kinase PF01513.21 KXS21844.1 - 3.4e-67 226.7 0.0 1.7e-66 224.4 0.0 2.0 1 1 0 1 1 1 1 ATP-NAD kinase Cupin_3 PF05899.12 KXS21844.1 - 0.076 12.7 0.0 14 5.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF861) DAGK_cat PF00781.24 KXS21844.1 - 0.13 11.9 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain SEP PF08059.13 KXS21845.1 - 7.5e-27 93.7 0.0 1.2e-26 93.0 0.0 1.3 1 0 0 1 1 1 1 SEP domain UBX PF00789.20 KXS21845.1 - 1.2e-16 60.6 0.0 1.8e-16 60.1 0.0 1.2 1 0 0 1 1 1 1 UBX domain Glyco_hydro_3_C PF01915.22 KXS21845.1 - 0.034 14.1 0.0 0.041 13.8 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain SR1P PF13790.6 KXS21846.1 - 0.018 15.1 3.2 0.023 14.8 0.1 2.4 2 0 0 2 2 2 0 SR1 protein ArfGap PF01412.18 KXS21847.1 - 7.4e-40 135.7 0.3 1e-39 135.2 0.3 1.2 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf IGPD PF00475.18 KXS21848.1 - 4.5e-64 215.1 0.4 5.9e-64 214.7 0.4 1.2 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase MRC1 PF09444.10 KXS21849.1 - 1.3e-25 90.6 9.5 1.3e-25 90.6 9.5 6.8 8 1 0 8 8 8 1 MRC1-like domain CSN5_C PF18323.1 KXS21849.1 - 2 9.4 5.3 14 6.7 2.6 3.8 2 0 0 2 2 2 0 Cop9 signalosome subunit 5 C-terminal domain Peptidase_A22B PF04258.13 KXS21850.1 - 1.3e-77 261.1 4.6 2.1e-77 260.4 4.6 1.3 1 0 0 1 1 1 1 Signal peptide peptidase SPP PF06550.11 KXS21850.1 - 2.9e-09 36.8 6.0 1.1e-08 34.9 5.2 1.9 2 0 0 2 2 2 1 Signal-peptide peptidase, presenilin aspartyl protease BRCT PF00533.26 KXS21851.1 - 1.3e-08 35.1 0.1 7.4e-05 23.1 0.1 2.3 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KXS21851.1 - 8.3e-07 29.3 0.0 0.012 16.0 0.0 2.1 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 KXS21851.1 - 2.5e-06 27.3 0.0 3.7e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain FHA PF00498.26 KXS21852.1 - 1.9e-06 28.1 0.0 5.8e-06 26.6 0.0 1.8 2 0 0 2 2 2 1 FHA domain API5 PF05918.11 KXS21852.1 - 0.47 9.2 13.5 0.17 10.7 6.9 2.2 2 0 0 2 2 2 0 Apoptosis inhibitory protein 5 (API5) DUF5549 PF17703.1 KXS21852.1 - 5.3 6.6 12.3 1 9.0 4.5 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5549) Polysacc_deac_1 PF01522.21 KXS21855.1 - 1.5e-19 70.1 0.0 2e-19 69.7 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase Polysacc_deac_2 PF04748.13 KXS21855.1 - 0.0054 15.9 0.0 0.0078 15.4 0.0 1.3 1 0 0 1 1 1 1 Divergent polysaccharide deacetylase Acyl-CoA_dh_1 PF00441.24 KXS21857.1 - 2e-27 96.3 0.2 2.9e-27 95.7 0.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KXS21857.1 - 6.7e-21 74.3 0.1 1.3e-20 73.4 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.28 KXS21857.1 - 2e-18 66.3 0.0 5e-18 65.0 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.16 KXS21857.1 - 1.2e-12 48.5 0.0 6.1e-12 46.2 0.0 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KXS21857.1 - 0.00011 22.5 0.0 0.0002 21.6 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain YqaJ PF09588.10 KXS21858.1 - 0.00073 19.7 0.0 0.0015 18.7 0.0 1.5 1 0 0 1 1 1 1 YqaJ-like viral recombinase domain NICE-1 PF15845.5 KXS21858.1 - 0.077 13.8 4.0 0.39 11.5 0.1 2.8 2 1 1 3 3 3 0 Cysteine-rich C-terminal 1 family YqaJ PF09588.10 KXS21859.1 - 1.3e-06 28.7 0.0 2.9e-06 27.5 0.0 1.6 1 1 0 1 1 1 1 YqaJ-like viral recombinase domain Sugar_tr PF00083.24 KXS21860.1 - 3.3e-53 181.2 20.2 4e-53 180.9 20.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXS21860.1 - 1.2e-25 90.2 31.0 4.6e-25 88.3 26.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KXS21860.1 - 8.3e-06 25.3 6.5 8.3e-06 25.3 6.5 2.1 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB adh_short PF00106.25 KXS21861.1 - 3.5e-46 157.1 0.0 4.9e-46 156.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXS21861.1 - 8e-29 100.8 0.0 1.2e-28 100.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXS21861.1 - 8e-11 42.2 0.7 6.8e-10 39.2 0.7 2.0 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KXS21861.1 - 0.0018 17.8 0.0 0.004 16.6 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.8 KXS21861.1 - 0.0056 16.4 0.2 0.012 15.3 0.2 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 3Beta_HSD PF01073.19 KXS21861.1 - 0.091 11.7 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Caveolin PF01146.17 KXS21861.1 - 0.12 12.3 1.8 0.31 11.0 1.8 1.6 1 0 0 1 1 1 0 Caveolin GTP_EFTU PF00009.27 KXS21863.1 - 1.4e-58 197.6 0.0 3.6e-58 196.3 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 KXS21863.1 - 5.3e-39 132.7 0.1 1.1e-38 131.8 0.1 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.6 KXS21863.1 - 8.5e-35 118.7 0.1 1.7e-34 117.8 0.1 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 KXS21863.1 - 4.1e-23 81.2 0.1 1.4e-22 79.5 0.1 2.0 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KXS21863.1 - 2.9e-13 50.0 0.9 5.6e-13 49.1 0.3 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 RF3_C PF16658.5 KXS21863.1 - 2e-07 30.9 0.0 4.1e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain AvrPtoB_bdg PF16847.5 KXS21863.1 - 0.0019 18.6 0.0 0.061 13.8 0.0 2.8 3 0 0 3 3 3 1 Avirulence AvrPtoB, BAK1-binding domain DUF442 PF04273.13 KXS21863.1 - 0.0084 16.2 0.0 7.1 6.8 0.0 2.8 2 0 0 2 2 2 2 Putative phosphatase (DUF442) MMR_HSR1 PF01926.23 KXS21863.1 - 0.04 14.0 0.0 0.12 12.5 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase Sec1 PF00995.23 KXS21864.1 - 2e-124 417.0 1.5 2.2e-124 416.8 1.5 1.0 1 0 0 1 1 1 1 Sec1 family Pox_VLTF3 PF04947.14 KXS21864.1 - 0.03 14.1 0.6 4.5 7.0 0.3 2.5 1 1 1 2 2 2 0 Poxvirus Late Transcription Factor VLTF3 like DUF5339 PF17274.2 KXS21864.1 - 0.17 12.8 0.5 12 6.9 0.0 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5339) SAP PF02037.27 KXS21865.1 - 5.8e-12 45.1 1.2 1.3e-11 44.0 1.2 1.6 1 0 0 1 1 1 1 SAP domain Tho1_MOS11_C PF18592.1 KXS21865.1 - 8.3e-06 25.5 15.0 0.046 13.5 0.1 4.1 2 2 2 4 4 4 3 Tho1/MOS11 C-terminal domain Telomere_Sde2_2 PF13297.6 KXS21865.1 - 0.18 11.5 0.2 0.18 11.5 0.2 1.9 2 0 0 2 2 2 0 Telomere stability C-terminal FSAP_sig_propep PF03032.15 KXS21865.1 - 0.35 10.9 4.2 5.5 7.1 0.2 2.9 3 0 0 3 3 3 0 Frog skin active peptide family signal and propeptide Glypican PF01153.19 KXS21865.1 - 0.4 9.5 6.6 0.047 12.5 1.9 1.7 2 0 0 2 2 2 0 Glypican Hamartin PF04388.12 KXS21865.1 - 1.2 7.8 14.6 1.4 7.5 14.6 1.1 1 0 0 1 1 1 0 Hamartin protein Packaging_FI PF14000.6 KXS21865.1 - 5.2 7.5 9.1 0.68 10.4 2.9 2.4 2 1 0 2 2 2 0 DNA packaging protein FI TFIIA PF03153.13 KXS21865.1 - 5.4 6.9 15.3 6.6 6.6 15.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit LSM PF01423.22 KXS21866.1 - 1.3e-20 72.8 0.1 1.5e-20 72.7 0.1 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KXS21866.1 - 0.0013 18.8 0.0 0.0015 18.6 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain Pkinase PF00069.25 KXS21867.1 - 6.7e-71 238.7 0.0 8.2e-71 238.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS21867.1 - 1.9e-49 168.3 0.0 2.3e-49 168.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXS21867.1 - 0.0032 16.8 0.0 0.023 14.0 0.0 2.0 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 KXS21867.1 - 0.007 16.0 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 KXS21867.1 - 0.02 13.7 0.0 0.031 13.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 KXS21867.1 - 0.064 12.6 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KXS21867.1 - 0.079 12.6 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 IQ PF00612.27 KXS21868.1 - 1.2e-06 27.8 0.3 2.7e-06 26.7 0.3 1.6 1 0 0 1 1 1 1 IQ calmodulin-binding motif LPP PF04728.13 KXS21868.1 - 0.41 11.1 11.7 0.56 10.6 0.2 4.4 4 0 0 4 4 4 0 Lipoprotein leucine-zipper Fib_alpha PF08702.10 KXS21868.1 - 1.2 9.3 22.3 3.2 7.9 3.4 3.4 1 1 1 3 3 3 0 Fibrinogen alpha/beta chain family tRNA-synt_2 PF00152.20 KXS21869.1 - 3.2e-69 233.4 0.0 4.4e-69 233.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KXS21869.1 - 1.2e-10 41.2 0.0 2.1e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KXS21869.1 - 1.1e-09 38.2 0.0 0.00017 21.2 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) CREPT PF16566.5 KXS21871.1 - 0.013 15.7 2.0 0.013 15.7 2.0 3.9 1 1 3 4 4 4 0 Cell-cycle alteration and expression-elevated protein in tumour KxDL PF10241.9 KXS21871.1 - 0.29 11.5 7.6 1.1 9.5 0.5 3.4 3 0 0 3 3 3 0 Uncharacterized conserved protein TMPIT PF07851.13 KXS21871.1 - 0.8 8.9 11.1 0.1 11.9 1.4 2.3 2 1 0 2 2 2 0 TMPIT-like protein Sec34 PF04136.15 KXS21871.1 - 7.1 6.5 6.7 1.4 8.8 0.1 2.7 3 1 0 3 3 3 0 Sec34-like family GATase_5 PF13507.6 KXS21873.1 - 1.5e-94 316.0 0.0 2.3e-94 315.3 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 KXS21873.1 - 1.2e-41 142.4 0.0 4.7e-32 111.3 0.0 3.5 4 0 0 4 4 4 2 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 KXS21873.1 - 1.3e-25 89.7 0.0 2.9e-25 88.5 0.0 1.6 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal FGAR-AT_linker PF18072.1 KXS21873.1 - 2.3e-18 66.5 0.0 5e-18 65.4 0.0 1.6 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain VASP_tetra PF08776.11 KXS21873.1 - 0.067 12.8 0.1 0.21 11.2 0.1 1.8 1 0 0 1 1 1 0 VASP tetramerisation domain AIRS PF00586.24 KXS21873.1 - 0.075 13.7 0.5 0.83 10.3 0.0 2.5 2 0 0 2 2 2 0 AIR synthase related protein, N-terminal domain Methyltransf_12 PF08242.12 KXS21874.1 - 6.6e-06 26.8 0.1 0.022 15.5 0.1 3.3 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 KXS21874.1 - 0.0025 18.5 0.0 0.071 13.8 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Phage_holin_8 PF16931.5 KXS21874.1 - 0.03 14.3 0.4 0.057 13.4 0.4 1.4 1 0 0 1 1 1 0 Putative phage holin FAD_binding_7 PF03441.14 KXS21874.1 - 0.097 12.1 0.1 0.15 11.6 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain of DNA photolyase DER1 PF04511.15 KXS21877.1 - 1.4e-54 184.9 8.7 1.6e-54 184.8 8.7 1.0 1 0 0 1 1 1 1 Der1-like family Oxidored_q3 PF00499.20 KXS21877.1 - 0.0027 17.4 2.7 0.0044 16.7 2.7 1.3 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 Fungal_trans PF04082.18 KXS21878.1 - 3.5e-23 82.0 0.0 6.5e-23 81.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXS21878.1 - 1.5e-05 25.0 12.1 2.5e-05 24.3 12.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UnbV_ASPIC PF07593.12 KXS21878.1 - 0.16 11.9 0.0 0.34 10.9 0.0 1.4 1 0 0 1 1 1 0 ASPIC and UnbV ECH_1 PF00378.20 KXS21879.1 - 9.3e-57 192.2 0.0 1.2e-56 191.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXS21879.1 - 9.3e-31 107.5 1.3 2.1e-29 103.1 0.5 2.1 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 KXS21879.1 - 0.00046 20.2 0.1 1 9.3 0.0 2.3 2 0 0 2 2 2 2 Peptidase family S49 CwsA PF10814.8 KXS21879.1 - 0.87 9.8 4.2 0.65 10.2 1.4 2.1 1 1 1 2 2 2 0 Cell wall synthesis protein CwsA IFT57 PF10498.9 KXS21880.1 - 1.3e-06 27.7 2.1 1.5e-06 27.4 2.1 1.1 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 ATG16 PF08614.11 KXS21880.1 - 6.8e-06 26.4 4.8 8.7e-06 26.1 4.8 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) DUF812 PF05667.11 KXS21880.1 - 9.8e-05 21.4 2.9 0.00011 21.3 2.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Spc7 PF08317.11 KXS21880.1 - 0.00045 19.2 6.3 0.00051 19.0 6.3 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein GAS PF13851.6 KXS21880.1 - 0.00048 19.5 10.9 0.00064 19.1 10.9 1.1 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding CALCOCO1 PF07888.11 KXS21880.1 - 0.00095 18.1 6.1 0.00095 18.1 6.1 1.0 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like Filament PF00038.21 KXS21880.1 - 0.0022 17.7 4.8 0.0029 17.2 4.8 1.2 1 0 0 1 1 1 1 Intermediate filament protein DUF4200 PF13863.6 KXS21880.1 - 0.0029 18.0 13.2 0.063 13.7 13.2 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF4200) Transcrip_act PF04949.13 KXS21880.1 - 0.0046 16.9 3.3 0.006 16.5 3.3 1.3 1 0 0 1 1 1 1 Transcriptional activator MscS_porin PF12795.7 KXS21880.1 - 0.0046 16.5 5.9 0.0062 16.1 5.9 1.1 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain Fez1 PF06818.15 KXS21880.1 - 0.01 16.3 6.9 0.013 15.9 6.9 1.1 1 0 0 1 1 1 0 Fez1 DUF3450 PF11932.8 KXS21880.1 - 0.013 14.8 7.1 0.018 14.3 7.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Uds1 PF15456.6 KXS21880.1 - 0.016 15.4 8.3 0.032 14.4 8.3 1.5 1 0 0 1 1 1 0 Up-regulated During Septation HIP1_clath_bdg PF16515.5 KXS21880.1 - 0.018 15.6 7.8 0.032 14.8 7.8 1.5 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF3972 PF13118.6 KXS21880.1 - 0.025 15.0 2.2 0.19 12.2 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3972) DUF724 PF05266.14 KXS21880.1 - 0.048 13.5 8.2 0.071 12.9 8.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF4407 PF14362.6 KXS21880.1 - 0.05 13.0 4.5 0.058 12.7 4.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FlaC_arch PF05377.11 KXS21880.1 - 0.064 13.7 1.2 0.14 12.5 0.6 2.0 1 1 1 2 2 1 0 Flagella accessory protein C (FlaC) Prominin PF05478.11 KXS21880.1 - 0.075 11.0 1.2 0.09 10.7 1.2 1.0 1 0 0 1 1 1 0 Prominin Lebercilin PF15619.6 KXS21880.1 - 0.079 12.6 11.7 0.048 13.3 3.6 2.1 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease CENP-H PF05837.12 KXS21880.1 - 0.1 13.0 9.1 0.17 12.3 9.1 1.3 1 0 0 1 1 1 0 Centromere protein H (CENP-H) IFT20 PF14931.6 KXS21880.1 - 0.12 12.5 7.3 0.18 12.0 7.3 1.3 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 Wtap PF17098.5 KXS21880.1 - 0.13 12.2 6.9 0.8 9.6 1.5 2.2 2 0 0 2 2 2 0 WTAP/Mum2p family TPR_MLP1_2 PF07926.12 KXS21880.1 - 0.13 12.3 13.2 0.06 13.4 7.0 2.1 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein PDCD7 PF16021.5 KXS21880.1 - 0.15 11.2 8.8 0.2 10.7 8.8 1.1 1 0 0 1 1 1 0 Programmed cell death protein 7 DUF1664 PF07889.12 KXS21880.1 - 0.17 11.9 1.0 0.24 11.4 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) ADIP PF11559.8 KXS21880.1 - 0.2 11.8 10.8 0.35 10.9 10.2 1.7 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF16 PF01519.16 KXS21880.1 - 0.3 11.6 4.2 0.47 11.0 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF16 Mod_r PF07200.13 KXS21880.1 - 0.37 10.9 8.4 3.9 7.6 8.4 2.1 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein YabA PF06156.13 KXS21880.1 - 0.41 11.3 4.2 0.67 10.6 4.2 1.4 1 0 0 1 1 1 0 Initiation control protein YabA Syntaxin-6_N PF09177.11 KXS21880.1 - 0.48 11.0 3.7 1 9.9 3.6 1.6 1 1 0 1 1 1 0 Syntaxin 6, N-terminal DUF4140 PF13600.6 KXS21880.1 - 0.69 10.4 8.5 46 4.5 8.5 2.8 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) TMPIT PF07851.13 KXS21880.1 - 0.92 8.7 2.9 1.2 8.4 2.9 1.1 1 0 0 1 1 1 0 TMPIT-like protein APG6_N PF17675.1 KXS21880.1 - 1.2 9.7 16.2 13 6.3 15.9 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region OmpH PF03938.14 KXS21880.1 - 1.5 9.1 9.8 2.9 8.2 9.7 1.5 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DivIC PF04977.15 KXS21880.1 - 2.3 8.1 12.0 15 5.5 8.4 2.8 1 1 2 3 3 3 0 Septum formation initiator THOC7 PF05615.13 KXS21880.1 - 2.4 8.4 12.1 5.9 7.2 9.8 2.5 1 1 1 2 2 2 0 Tho complex subunit 7 Spc24 PF08286.11 KXS21880.1 - 3.7 7.8 9.2 1.8e+02 2.4 9.2 2.3 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 Seryl_tRNA_N PF02403.22 KXS21880.1 - 4.8 7.4 11.1 17 5.7 2.4 2.0 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain ILVD_EDD PF00920.21 KXS21881.1 - 7.9e-153 509.8 0.0 9.5e-153 509.5 0.0 1.0 1 0 0 1 1 1 1 Dehydratase family HTH_24 PF13412.6 KXS21881.1 - 0.19 11.3 0.1 1.1 8.8 0.0 2.3 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding adh_short PF00106.25 KXS21882.1 - 2.2e-05 24.0 0.0 4e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXS21882.1 - 0.0017 17.9 0.0 0.0031 17.1 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Pkinase PF00069.25 KXS21883.1 - 1.2e-69 234.6 0.0 1.4e-69 234.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS21883.1 - 1.1e-31 110.1 0.0 1.4e-31 109.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXS21883.1 - 4.3e-06 26.2 0.0 6.2e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KXS21883.1 - 0.00017 21.6 0.0 0.001 19.1 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KXS21883.1 - 0.00041 19.8 0.0 0.00085 18.7 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 KXS21883.1 - 0.021 14.3 0.1 0.047 13.2 0.0 1.5 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Pkinase_fungal PF17667.1 KXS21883.1 - 0.029 13.2 0.0 0.049 12.4 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase DAO PF01266.24 KXS21884.1 - 1.4e-40 140.0 11.6 1.8e-22 80.5 1.8 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXS21884.1 - 1.6e-05 24.3 0.0 0.002 17.4 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXS21884.1 - 0.0015 18.5 0.4 0.017 15.1 0.1 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KXS21884.1 - 0.0019 18.4 1.1 0.0047 17.1 1.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KXS21884.1 - 0.0022 18.5 0.5 0.004 17.7 0.5 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KXS21884.1 - 0.008 15.1 0.8 0.011 14.6 0.8 1.1 1 0 0 1 1 1 1 Tryptophan halogenase Thi4 PF01946.17 KXS21884.1 - 0.033 13.4 0.2 0.074 12.3 0.2 1.5 1 0 0 1 1 1 0 Thi4 family Sacchrp_dh_NADP PF03435.18 KXS21884.1 - 0.13 12.5 0.3 0.21 11.8 0.3 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain GAS PF13851.6 KXS21885.1 - 1e-66 224.1 16.6 1e-66 224.1 16.6 3.4 2 1 2 4 4 4 1 Growth-arrest specific micro-tubule binding MaoC_dehydratas PF01575.19 KXS21886.1 - 1.9e-27 95.3 0.0 3.2e-27 94.5 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 KXS21886.1 - 4.2e-08 33.4 0.0 1.3e-05 25.4 0.0 2.5 2 1 0 2 2 2 2 N-terminal half of MaoC dehydratase RabGAP-TBC PF00566.18 KXS21888.1 - 2.6e-10 40.3 0.0 6.4e-09 35.8 0.0 2.0 2 0 0 2 2 2 2 Rab-GTPase-TBC domain SET PF00856.28 KXS21889.1 - 1.5e-06 28.7 0.0 8.7e-06 26.2 0.0 2.2 1 1 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.11 KXS21889.1 - 2.9e-05 24.7 0.3 9.8e-05 23.1 0.0 2.0 2 1 0 2 2 2 1 Rubisco LSMT substrate-binding BshC PF10079.9 KXS21889.1 - 0.034 12.9 0.1 0.052 12.3 0.1 1.2 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC CUE PF02845.16 KXS21891.1 - 6.8e-05 22.5 0.1 0.00011 21.8 0.1 1.3 1 0 0 1 1 1 1 CUE domain FoP_duplication PF13865.6 KXS21891.1 - 5.5 7.6 14.3 0.93 10.1 9.8 2.0 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 Cyt-b5 PF00173.28 KXS21892.1 - 2.6e-12 46.7 0.0 2.9e-12 46.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain SurA_N_3 PF13624.6 KXS21893.1 - 0.18 11.6 1.3 2.2 8.0 0.1 2.7 1 1 0 2 2 2 0 SurA N-terminal domain Beta-Casp PF10996.8 KXS21895.1 - 4e-23 81.8 0.0 7.7e-23 80.9 0.0 1.5 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.12 KXS21895.1 - 1.6e-17 63.2 0.0 2.7e-17 62.5 0.0 1.4 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_6 PF16661.5 KXS21895.1 - 4e-17 62.3 0.0 1.3e-15 57.3 0.0 2.3 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 KXS21895.1 - 8.3e-09 35.2 0.0 1.6e-07 31.0 0.0 2.4 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KXS21895.1 - 7.5e-08 32.6 1.3 7.1e-07 29.4 0.3 2.9 3 1 0 3 3 3 1 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.6 KXS21895.1 - 0.00018 21.4 0.0 0.00055 19.9 0.0 1.7 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Beta_lactamase3 PF17030.5 KXS21895.1 - 0.0064 15.8 0.0 0.022 14.0 0.0 1.8 1 1 0 1 1 1 1 Putative beta-lactamase-like family ANAPC3 PF12895.7 KXS21896.1 - 0.00058 20.0 0.0 0.052 13.8 0.0 2.5 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 SRP_TPR_like PF17004.5 KXS21896.1 - 0.15 12.1 0.0 3.2 7.8 0.0 2.3 1 1 1 2 2 2 0 Putative TPR-like repeat TPR_6 PF13174.6 KXS21896.1 - 0.22 12.3 0.5 1.2e+02 3.6 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Fanconi_C PF02106.15 KXS21898.1 - 0.00069 18.5 0.0 0.0011 17.8 0.0 1.4 1 0 0 1 1 1 1 Fanconi anaemia group C protein HSA PF07529.13 KXS21899.1 - 1.4e-15 57.4 1.2 1.4e-15 57.4 1.2 2.0 2 0 0 2 2 2 1 HSA Myb_DNA-bind_6 PF13921.6 KXS21899.1 - 1.8e-08 34.5 0.0 5.1e-08 33.1 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KXS21899.1 - 8.2e-05 22.7 0.4 0.00016 21.8 0.4 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 KXS21899.1 - 0.15 12.3 0.1 0.3 11.3 0.1 1.5 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 DUF3188 PF11384.8 KXS21900.1 - 0.038 13.7 0.7 0.18 11.5 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3188) Prefoldin PF02996.17 KXS21901.1 - 6.2e-20 71.3 5.2 1e-18 67.4 3.9 2.3 1 1 1 2 2 2 2 Prefoldin subunit Prefoldin_2 PF01920.20 KXS21901.1 - 0.012 15.6 3.7 1.4 8.9 0.1 2.4 2 0 0 2 2 2 0 Prefoldin subunit Mst1_SARAH PF11629.8 KXS21901.1 - 0.026 14.6 0.2 0.089 12.9 0.2 1.9 1 0 0 1 1 1 0 C terminal SARAH domain of Mst1 WXG100 PF06013.12 KXS21901.1 - 0.086 13.1 4.4 1.4 9.2 0.6 2.4 2 0 0 2 2 2 0 Proteins of 100 residues with WXG FliJ PF02050.16 KXS21901.1 - 0.09 13.0 10.6 0.79 10.0 2.0 2.2 2 0 0 2 2 2 0 Flagellar FliJ protein HIP1_clath_bdg PF16515.5 KXS21901.1 - 0.6 10.7 9.0 2.7 8.6 3.1 2.4 2 1 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 RasGAP_C PF03836.15 KXS21901.1 - 0.93 9.6 7.1 1.7 8.8 1.5 2.2 2 0 0 2 2 2 0 RasGAP C-terminus Uso1_p115_C PF04871.13 KXS21901.1 - 1.9 8.8 9.9 0.27 11.6 1.7 2.3 2 1 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region 14-3-3 PF00244.20 KXS21902.1 - 1.7e-106 354.7 6.6 1.9e-106 354.5 6.6 1.0 1 0 0 1 1 1 1 14-3-3 protein Orbi_VP5 PF00901.17 KXS21902.1 - 0.14 10.5 4.0 0.22 9.9 4.0 1.3 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 PP2C PF00481.21 KXS21903.1 - 5.8e-71 239.1 0.0 8.7e-71 238.6 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 KXS21903.1 - 0.00014 21.6 0.0 0.00039 20.1 0.0 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C Septin PF00735.18 KXS21904.1 - 3.6e-110 367.7 0.6 4.9e-110 367.2 0.6 1.2 1 0 0 1 1 1 1 Septin GTP_EFTU PF00009.27 KXS21904.1 - 1.8e-08 34.2 2.1 1.3e-06 28.1 0.0 2.6 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KXS21904.1 - 3.1e-08 33.7 0.0 5.8e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KXS21904.1 - 1.6e-06 28.1 0.0 0.00041 20.3 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_24 PF13479.6 KXS21904.1 - 1.8e-06 27.8 1.3 5.6e-06 26.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain Pox_A32 PF04665.12 KXS21904.1 - 1.9e-05 24.3 0.0 3.4e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Poxvirus A32 protein FtsK_SpoIIIE PF01580.18 KXS21904.1 - 4.5e-05 22.9 1.5 0.00018 21.0 0.0 2.2 2 0 0 2 2 2 1 FtsK/SpoIIIE family Ras PF00071.22 KXS21904.1 - 6.1e-05 22.7 0.3 0.00017 21.2 0.3 1.8 1 1 0 1 1 1 1 Ras family AAA_22 PF13401.6 KXS21904.1 - 0.00012 22.4 0.0 0.0005 20.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain AIG1 PF04548.16 KXS21904.1 - 0.00026 20.4 0.8 0.00079 18.8 0.0 2.1 2 0 0 2 2 2 1 AIG1 family AAA_16 PF13191.6 KXS21904.1 - 0.00036 21.0 0.1 0.0017 18.8 0.0 2.0 2 1 0 2 2 2 1 AAA ATPase domain T2SSE PF00437.20 KXS21904.1 - 0.0006 19.0 0.0 0.0019 17.3 0.0 1.7 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_23 PF13476.6 KXS21904.1 - 0.00061 20.3 1.0 0.042 14.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain G-alpha PF00503.20 KXS21904.1 - 0.00067 18.9 0.2 0.00086 18.6 0.2 1.6 1 1 0 1 1 1 1 G-protein alpha subunit AAA_7 PF12775.7 KXS21904.1 - 0.001 18.6 0.0 0.0028 17.2 0.0 1.8 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_29 PF13555.6 KXS21904.1 - 0.0023 17.7 0.0 0.0043 16.8 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain IIGP PF05049.13 KXS21904.1 - 0.0024 17.0 0.0 0.0043 16.2 0.0 1.4 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) Roc PF08477.13 KXS21904.1 - 0.0029 17.8 0.0 0.0093 16.2 0.0 1.9 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase NACHT PF05729.12 KXS21904.1 - 0.0033 17.3 0.0 0.0084 16.0 0.0 1.7 1 0 0 1 1 1 1 NACHT domain RNA_helicase PF00910.22 KXS21904.1 - 0.004 17.5 0.0 0.014 15.8 0.0 2.0 1 1 0 1 1 1 1 RNA helicase ABC_tran PF00005.27 KXS21904.1 - 0.0043 17.6 0.5 0.016 15.7 0.0 2.1 2 0 0 2 2 2 1 ABC transporter DUF3987 PF13148.6 KXS21904.1 - 0.012 14.6 0.3 0.063 12.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) PRK PF00485.18 KXS21904.1 - 0.014 15.1 0.0 0.042 13.6 0.0 1.7 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_32 PF13654.6 KXS21904.1 - 0.018 13.8 0.1 0.018 13.8 0.1 2.2 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 KXS21904.1 - 0.021 14.6 0.3 0.19 11.5 0.1 2.5 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein DUF463 PF04317.12 KXS21904.1 - 0.029 13.3 0.2 0.2 10.5 0.0 2.0 2 0 0 2 2 2 0 YcjX-like family, DUF463 Sigma54_activat PF00158.26 KXS21904.1 - 0.037 13.7 0.0 0.07 12.8 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_33 PF13671.6 KXS21904.1 - 0.037 14.2 0.1 0.24 11.6 0.0 2.3 2 1 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 KXS21904.1 - 0.037 13.8 0.1 1.1 8.9 0.0 2.8 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.23 KXS21904.1 - 0.048 13.7 6.7 0.43 10.6 0.3 3.1 2 1 1 3 3 3 0 Dynamin family AAA_19 PF13245.6 KXS21904.1 - 0.057 13.8 0.1 0.34 11.2 0.0 2.0 2 1 0 2 2 2 0 AAA domain KAP_NTPase PF07693.14 KXS21904.1 - 0.068 12.4 0.0 0.17 11.1 0.0 1.8 1 1 0 1 1 1 0 KAP family P-loop domain MobB PF03205.14 KXS21904.1 - 0.072 13.0 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF87 PF01935.17 KXS21904.1 - 0.082 13.0 0.3 0.59 10.2 0.0 2.2 2 0 0 2 2 2 0 Helicase HerA, central domain Mg_chelatase PF01078.21 KXS21904.1 - 0.12 11.7 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI cobW PF02492.19 KXS21904.1 - 0.12 11.9 0.0 0.39 10.3 0.0 2.0 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain CLP1_P PF16575.5 KXS21904.1 - 0.14 11.9 0.1 11 5.8 0.1 2.4 1 1 1 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Viral_helicase1 PF01443.18 KXS21904.1 - 0.15 11.8 0.0 0.36 10.5 0.0 1.7 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_18 PF13238.6 KXS21904.1 - 0.22 12.1 2.8 1.5 9.4 0.1 3.0 3 2 0 3 3 3 0 AAA domain AAA_11 PF13086.6 KXS21904.1 - 1.4 8.6 4.8 8.5 6.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF4303 PF14136.6 KXS21904.1 - 1.9 8.2 8.7 5.5 6.7 3.3 2.7 2 1 1 3 3 2 0 Domain of unknown function (DUF4303) Pkinase PF00069.25 KXS21905.1 - 3.6e-27 95.4 0.0 4.3e-27 95.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS21905.1 - 7.9e-16 58.1 0.0 9.7e-16 57.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXS21905.1 - 3.8e-10 39.1 0.0 5.3e-10 38.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KXS21905.1 - 0.0024 17.8 0.0 0.016 15.1 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 KXS21905.1 - 0.0092 15.0 0.1 0.013 14.5 0.1 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Kdo PF06293.14 KXS21905.1 - 0.065 12.6 0.1 0.11 11.9 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SNF2_N PF00176.23 KXS21906.1 - 1.1e-45 155.9 0.0 1.6e-45 155.3 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KXS21906.1 - 1.4e-11 44.7 0.0 3.6e-11 43.4 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXS21906.1 - 0.00083 19.4 0.0 0.0016 18.5 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit BRCT_2 PF16589.5 KXS21906.1 - 0.025 15.0 0.0 0.057 13.8 0.0 1.6 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain HDA2-3 PF11496.8 KXS21906.1 - 0.23 10.6 0.0 0.65 9.1 0.0 1.7 2 0 0 2 2 2 0 Class II histone deacetylase complex subunits 2 and 3 DUF4743 PF15916.5 KXS21909.1 - 5.5e-16 58.6 0.0 1.6e-13 50.7 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4743) NUDIX PF00293.28 KXS21909.1 - 1.7e-09 37.8 0.0 3e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain DUF936 PF06075.12 KXS21910.1 - 0.21 10.5 0.7 0.16 10.9 0.7 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) Pkinase PF00069.25 KXS21912.1 - 1.1e-07 31.5 0.0 1.6e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Ldh_1_N PF00056.23 KXS21913.1 - 2.5e-37 128.1 0.3 3.9e-37 127.5 0.3 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 KXS21913.1 - 8.5e-21 74.6 0.0 1.5e-20 73.8 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain ApbA PF02558.16 KXS21913.1 - 0.00014 21.5 0.3 0.00076 19.1 0.3 2.0 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 KXS21913.1 - 0.0011 19.5 0.7 0.0088 16.6 0.9 2.2 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 KXS21913.1 - 0.0014 18.6 1.5 0.0044 16.9 1.4 1.9 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ThiF PF00899.21 KXS21913.1 - 0.0061 15.9 0.3 0.011 15.1 0.3 1.4 1 0 0 1 1 1 1 ThiF family DAO PF01266.24 KXS21913.1 - 0.024 14.2 3.0 0.038 13.6 2.4 1.5 1 1 0 1 1 1 0 FAD dependent oxidoreductase PALP PF00291.25 KXS21913.1 - 0.039 13.4 0.4 0.076 12.4 0.3 1.5 2 0 0 2 2 2 0 Pyridoxal-phosphate dependent enzyme AlaDh_PNT_C PF01262.21 KXS21913.1 - 0.097 11.9 1.9 0.14 11.4 1.9 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 KXS21913.1 - 0.12 12.0 1.0 0.33 10.5 0.9 1.9 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Glyco_hydro_4 PF02056.16 KXS21913.1 - 0.12 11.9 0.7 0.65 9.5 0.1 2.1 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase Ribosomal_S15 PF00312.22 KXS21914.1 - 2.4e-18 66.1 0.3 4.3e-18 65.3 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein S15 LrgB PF04172.16 KXS21915.1 - 5.2e-48 163.4 12.6 5.2e-48 163.4 12.6 2.5 2 1 0 2 2 2 1 LrgB-like family LrgA PF03788.14 KXS21915.1 - 0.0071 16.3 15.7 0.015 15.2 10.7 3.1 2 0 0 2 2 2 1 LrgA family CPP1-like PF11833.8 KXS21915.1 - 0.06 13.0 0.1 0.06 13.0 0.1 2.8 3 1 0 3 3 3 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Nup88 PF10168.9 KXS21917.1 - 1.4e-06 26.4 0.0 2.1e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 Nuclear pore component MaoC_dehydratas PF01575.19 KXS21918.1 - 9.3e-31 106.0 0.0 1.4e-30 105.4 0.0 1.2 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 KXS21918.1 - 0.00022 21.4 0.0 0.11 12.6 0.0 2.3 2 1 0 2 2 2 2 N-terminal half of MaoC dehydratase eIF_4EBP PF05456.11 KXS21918.1 - 0.032 14.1 0.1 0.079 12.9 0.1 1.6 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) NAD_binding_10 PF13460.6 KXS21919.1 - 6.3e-11 42.5 0.0 9.2e-10 38.7 0.0 2.3 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KXS21919.1 - 0.0051 16.4 0.0 0.0084 15.7 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Peripla_BP_3 PF13377.6 KXS21919.1 - 0.11 12.8 0.1 0.16 12.3 0.1 1.3 1 0 0 1 1 1 0 Periplasmic binding protein-like domain Ribosomal_S13_N PF08069.12 KXS21921.1 - 1.8e-30 104.7 0.1 3.3e-30 103.9 0.1 1.4 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 KXS21921.1 - 1.4e-13 50.9 0.2 2.5e-13 50.1 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.18 KXS21921.1 - 0.053 13.4 0.0 0.13 12.2 0.0 1.7 2 1 0 2 2 2 0 'Paired box' domain Phosphodiest PF01663.22 KXS21922.1 - 1.3e-06 28.3 0.8 2.4e-06 27.4 0.8 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase UL40 PF10682.9 KXS21923.1 - 0.04 13.6 0.0 0.056 13.1 0.0 1.1 1 0 0 1 1 1 0 Glycoprotein of human cytomegalovirus HHV-5 zf-MYND PF01753.18 KXS21924.1 - 1.6e-06 28.1 11.7 3.3e-06 27.1 11.7 1.6 1 1 0 1 1 1 1 MYND finger GDP_Man_Dehyd PF16363.5 KXS21925.1 - 2.7e-75 253.8 0.0 3.5e-75 253.5 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KXS21925.1 - 1.4e-63 214.6 0.2 1.7e-63 214.3 0.2 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXS21925.1 - 1.6e-23 83.1 0.0 2e-23 82.8 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KXS21925.1 - 2e-22 79.7 0.0 1.4e-21 76.9 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KXS21925.1 - 3.2e-20 72.4 0.0 4.3e-20 72.0 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 KXS21925.1 - 7.2e-20 71.2 0.0 6.9e-19 68.0 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 KXS21925.1 - 8.6e-08 32.3 0.0 4.8e-07 29.8 0.0 2.1 1 1 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 KXS21925.1 - 0.12 11.8 0.0 6.3 6.2 0.0 2.2 2 0 0 2 2 2 0 short chain dehydrogenase Ank_3 PF13606.6 KXS21927.1 - 0.00057 20.1 0.0 0.07 13.7 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 KXS21927.1 - 0.0027 18.1 0.2 0.12 12.9 0.1 2.8 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.7 KXS21927.1 - 0.011 16.4 0.0 0.12 13.0 0.0 2.5 2 1 0 2 2 2 0 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXS21927.1 - 0.025 14.9 0.0 0.14 12.5 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXS21927.1 - 0.19 12.4 0.0 8 7.2 0.0 2.7 3 0 0 3 3 3 0 Ankyrin repeats (many copies) PPR_2 PF13041.6 KXS21928.1 - 1.2e-08 35.0 0.1 5.2e-07 29.8 0.0 2.5 2 0 0 2 2 2 1 PPR repeat family PPR PF01535.20 KXS21928.1 - 0.00024 21.1 0.6 0.03 14.6 0.1 3.7 4 0 0 4 4 4 1 PPR repeat Sigma70_ner PF04546.13 KXS21928.1 - 2.5 8.0 10.0 3.4 7.5 4.6 2.6 2 0 0 2 2 2 0 Sigma-70, non-essential region PhyH PF05721.13 KXS21930.1 - 5.5e-08 33.3 0.5 6.4e-07 29.8 0.5 2.0 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF4723 PF15851.5 KXS21930.1 - 0.051 13.7 0.3 0.051 13.7 0.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4723) BUD22 PF09073.10 KXS21931.1 - 0.0059 16.0 30.3 0.0075 15.7 30.3 1.3 1 0 0 1 1 1 1 BUD22 Macoilin PF09726.9 KXS21931.1 - 2.5 6.5 10.0 2.9 6.3 10.0 1.1 1 0 0 1 1 1 0 Macoilin family Apt1 PF10351.9 KXS21931.1 - 8.8 5.1 14.2 11 4.7 14.2 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain DEAD PF00270.29 KXS21932.1 - 5.7e-34 117.4 0.0 2e-17 63.5 0.0 2.2 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.15 KXS21932.1 - 8.3e-05 22.6 0.0 0.00016 21.8 0.0 1.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit T2SSE PF00437.20 KXS21932.1 - 0.02 14.0 0.0 0.028 13.5 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Epimerase PF01370.21 KXS21933.1 - 2.4e-18 66.5 0.5 5.1e-18 65.4 0.5 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXS21933.1 - 2e-14 53.3 0.0 2.5e-14 53.0 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KXS21933.1 - 2.9e-08 33.8 0.8 5.9e-08 32.8 0.8 1.5 1 1 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KXS21933.1 - 4e-08 32.7 0.0 0.00043 19.5 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein NmrA PF05368.13 KXS21933.1 - 7.6e-07 28.9 0.6 1.4e-06 28.1 0.6 1.4 1 0 0 1 1 1 1 NmrA-like family GDP_Man_Dehyd PF16363.5 KXS21933.1 - 9.6e-07 28.5 0.2 1.7e-06 27.7 0.2 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 KXS21933.1 - 0.00035 20.1 0.8 0.0021 17.6 0.7 2.2 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXS21933.1 - 0.0016 18.4 0.2 0.0038 17.2 0.2 1.6 1 1 0 1 1 1 1 KR domain ADH_zinc_N PF00107.26 KXS21933.1 - 0.0017 18.3 0.1 4.5 7.3 0.0 3.3 3 0 0 3 3 3 1 Zinc-binding dehydrogenase Polysacc_synt_2 PF02719.15 KXS21933.1 - 0.0045 16.2 0.0 0.0066 15.6 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein MTS PF05175.14 KXS21933.1 - 0.0088 15.6 0.0 0.016 14.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain HAD PF12710.7 KXS21933.1 - 0.0093 16.4 0.1 0.089 13.2 0.1 2.4 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase RmlD_sub_bind PF04321.17 KXS21933.1 - 0.015 14.4 0.0 1.5 7.9 0.0 2.3 2 0 0 2 2 2 0 RmlD substrate binding domain Pec_lyase_C PF00544.19 KXS21934.1 - 1.5e-44 152.1 1.8 3e-44 151.1 1.8 1.5 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 KXS21934.1 - 0.18 11.6 9.0 0.054 13.3 0.8 2.9 2 1 1 3 3 3 0 Right handed beta helix region Pec_lyase_C PF00544.19 KXS21936.1 - 1.6e-49 168.3 2.0 3.7e-49 167.2 2.0 1.6 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 KXS21936.1 - 0.0023 17.8 2.1 0.017 15.0 1.5 2.2 1 1 1 2 2 2 1 Right handed beta helix region TPR_16 PF13432.6 KXS21937.1 - 1.2e-06 29.1 9.8 0.0018 18.9 1.9 3.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 KXS21937.1 - 4.4e-06 26.4 0.9 0.006 16.6 0.2 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 KXS21937.1 - 0.00015 21.4 2.5 0.00062 19.4 0.1 2.9 3 0 0 3 3 3 1 TPR repeat TPR_8 PF13181.6 KXS21937.1 - 0.00064 19.7 0.4 6.2 7.3 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 KXS21937.1 - 0.0017 18.1 0.4 0.038 13.8 0.1 3.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 KXS21937.1 - 0.003 17.6 12.9 0.076 13.2 0.5 3.6 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KXS21937.1 - 0.0091 16.7 1.9 0.53 11.2 0.1 3.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 KXS21937.1 - 0.03 14.6 4.2 0.07 13.4 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 KXS21937.1 - 0.031 14.1 1.3 0.11 12.4 0.3 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 KXS21937.1 - 1.6 9.3 5.5 5.4 7.6 0.2 3.2 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 KXS21938.1 - 0.00022 21.1 1.3 0.87 9.9 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KXS21938.1 - 0.0039 16.9 0.0 0.7 9.8 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 KXS21938.1 - 0.0076 16.5 0.5 1.1 9.6 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 KXS21938.1 - 0.046 14.0 0.0 0.39 11.0 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat RPN7 PF10602.9 KXS21938.1 - 0.07 12.8 0.8 0.14 11.9 0.3 1.7 2 0 0 2 2 2 0 26S proteasome subunit RPN7 TPR_9 PF13371.6 KXS21938.1 - 0.22 11.7 4.4 3.5 7.8 0.4 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 KXS21938.1 - 1.9 9.2 6.2 26 5.6 1.0 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KXS21938.1 - 3.1 8.8 7.7 27 5.9 0.2 3.9 3 1 1 4 4 4 0 Tetratricopeptide repeat RSN1_7TM PF02714.15 KXS21939.1 - 2.8e-45 154.8 17.7 2.8e-45 154.8 17.7 1.5 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KXS21939.1 - 5.3e-20 71.8 0.2 5.3e-20 71.8 0.2 3.5 4 0 0 4 4 4 2 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KXS21939.1 - 2.8e-09 37.5 1.6 0.00033 20.9 0.1 2.7 3 0 0 3 3 3 2 Cytosolic domain of 10TM putative phosphate transporter PCYCGC PF13798.6 KXS21940.1 - 0.14 12.0 0.0 0.42 10.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function with PCYCGC motif TMEM107 PF14995.6 KXS21940.1 - 0.22 12.0 0.0 0.22 12.0 0.0 2.0 2 0 0 2 2 2 0 Transmembrane protein DUF3883 PF13020.6 KXS21941.1 - 2.8e-16 59.3 0.3 4.8e-16 58.6 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3883) HATPase_c_3 PF13589.6 KXS21942.1 - 1.3e-05 25.1 0.0 2.8e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PRP21_like_P PF12230.8 KXS21942.1 - 0.28 11.0 2.2 0.33 10.8 0.3 1.9 2 0 0 2 2 2 0 Pre-mRNA splicing factor PRP21 like protein DUF4853 PF16145.5 KXS21943.1 - 0.09 12.9 0.2 0.18 12.0 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4853) DUF3883 PF13020.6 KXS21944.1 - 5.4e-15 55.2 0.3 1.6e-14 53.7 0.3 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3883) Fungal_trans PF04082.18 KXS21946.1 - 3e-09 36.3 0.0 4.9e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain BAG PF02179.16 KXS21947.1 - 1.2e-07 32.0 0.1 1.8e-07 31.5 0.1 1.3 1 0 0 1 1 1 1 BAG domain UCH PF00443.29 KXS21948.1 - 2.2e-49 168.3 0.0 2.6e-49 168.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KXS21948.1 - 2.8e-13 50.2 0.0 3.6e-13 49.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf_UBZ PF18439.1 KXS21948.1 - 0.34 10.5 1.7 2.5 7.7 0.1 2.4 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger DIOX_N PF14226.6 KXS21949.1 - 7.1e-27 94.5 0.0 1.1e-26 93.9 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KXS21949.1 - 9.8e-21 74.1 0.0 1.7e-20 73.4 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CRAL_TRIO PF00650.20 KXS21951.1 - 1.7e-29 102.6 0.0 5.3e-28 97.7 0.0 2.1 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 KXS21951.1 - 0.00013 22.1 0.0 0.00022 21.4 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DUF3189 PF11385.8 KXS21951.1 - 0.16 11.9 0.0 0.25 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3189) BTB_2 PF02214.22 KXS21952.1 - 4.8e-07 30.0 0.0 5.9e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 BTB/POZ domain CorA PF01544.18 KXS21958.1 - 0.003 16.9 0.0 0.005 16.2 0.0 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein ABC_membrane PF00664.23 KXS21960.1 - 1.9e-96 322.9 32.9 4e-51 174.3 11.8 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KXS21960.1 - 1.2e-67 226.6 0.0 3.9e-33 114.9 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KXS21960.1 - 8e-12 45.1 9.6 2e-05 24.2 0.1 4.3 2 2 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KXS21960.1 - 3.3e-08 34.1 1.0 0.0045 17.4 0.0 2.9 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 KXS21960.1 - 2.4e-06 27.2 3.3 0.014 15.1 0.2 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain Zeta_toxin PF06414.12 KXS21960.1 - 1.2e-05 24.6 0.2 0.33 10.2 0.0 3.2 3 0 0 3 3 3 2 Zeta toxin AAA PF00004.29 KXS21960.1 - 1.5e-05 25.5 3.9 0.18 12.3 0.2 4.6 4 2 0 4 4 2 2 ATPase family associated with various cellular activities (AAA) AAA_21 PF13304.6 KXS21960.1 - 7.5e-05 22.7 0.5 1.3 8.8 0.0 3.5 2 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KXS21960.1 - 0.00011 22.5 0.4 0.28 11.4 0.0 3.5 3 1 0 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 KXS21960.1 - 0.00011 22.1 0.8 0.47 10.3 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase G-alpha PF00503.20 KXS21960.1 - 0.0002 20.7 0.0 0.025 13.8 0.0 2.3 2 0 0 2 2 2 1 G-protein alpha subunit DUF815 PF05673.13 KXS21960.1 - 0.0003 20.0 0.2 0.71 9.0 0.0 2.8 3 0 0 3 3 3 2 Protein of unknown function (DUF815) AAA_7 PF12775.7 KXS21960.1 - 0.00038 20.0 0.6 0.11 12.0 0.1 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_24 PF13479.6 KXS21960.1 - 0.0011 18.8 0.0 0.48 10.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KXS21960.1 - 0.0014 19.2 0.0 0.77 10.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KXS21960.1 - 0.0019 18.2 0.7 2 8.4 0.1 3.3 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_15 PF13175.6 KXS21960.1 - 0.0028 17.4 0.1 0.42 10.3 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 KXS21960.1 - 0.0046 17.1 0.1 0.87 9.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 KXS21960.1 - 0.0062 16.7 4.8 0.44 10.8 0.4 3.8 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Roc PF08477.13 KXS21960.1 - 0.011 16.0 0.1 2.9 8.1 0.1 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KXS21960.1 - 0.014 15.5 0.5 1.8 8.7 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_25 PF13481.6 KXS21960.1 - 0.028 14.0 0.5 3.4 7.2 0.1 2.8 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KXS21960.1 - 0.031 14.7 0.4 10 6.6 0.0 3.6 4 0 0 4 4 3 0 RNA helicase DUF87 PF01935.17 KXS21960.1 - 0.035 14.2 6.0 0.41 10.7 0.4 3.0 3 0 0 3 3 3 0 Helicase HerA, central domain ATP-synt_ab PF00006.25 KXS21960.1 - 0.041 13.5 0.2 0.32 10.6 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_28 PF13521.6 KXS21960.1 - 0.054 13.7 1.3 1.7 8.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 KXS21960.1 - 0.069 13.5 0.2 7.7 6.8 0.0 2.8 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 KXS21960.1 - 0.11 12.1 0.8 3.5 7.2 0.1 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain APS_kinase PF01583.20 KXS21960.1 - 0.11 12.3 0.1 14 5.5 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_30 PF13604.6 KXS21960.1 - 0.12 12.1 10.0 1.6 8.4 1.8 3.7 4 1 0 4 4 3 0 AAA domain FtsK_SpoIIIE PF01580.18 KXS21960.1 - 0.13 11.6 1.1 0.94 8.8 0.1 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family Rad17 PF03215.15 KXS21960.1 - 0.15 12.0 0.0 26 4.7 0.0 2.5 2 0 0 2 2 2 0 Rad17 P-loop domain ATP_bind_1 PF03029.17 KXS21960.1 - 0.2 11.4 0.9 15 5.2 0.1 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein ABC_ATPase PF09818.9 KXS21960.1 - 0.23 10.2 2.5 2.6 6.7 0.1 2.4 3 0 0 3 3 3 0 Predicted ATPase of the ABC class AAA_23 PF13476.6 KXS21960.1 - 0.63 10.5 5.1 13 6.2 0.0 3.2 3 0 0 3 3 3 0 AAA domain Sulfate_transp PF00916.20 KXS21961.1 - 3.5e-88 295.9 4.8 4.8e-88 295.5 4.8 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KXS21961.1 - 8.2e-14 51.2 0.0 1.4e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 KXS21961.1 - 0.055 13.8 0.0 0.15 12.4 0.0 1.7 1 0 0 1 1 1 0 STAS domain MFS_MOT1 PF16983.5 KXS21961.1 - 0.23 11.9 15.2 0.062 13.7 3.6 3.3 3 0 0 3 3 3 0 Molybdate transporter of MFS superfamily YjcB PF15940.5 KXS21961.1 - 4.2 7.6 7.2 11 6.3 0.5 3.3 2 1 1 3 3 3 0 Family of unknown function Kinesin PF00225.23 KXS21962.1 - 1.2e-89 300.5 0.1 2.8e-89 299.3 0.1 1.7 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KXS21962.1 - 1.4e-11 44.5 0.3 1.1e-10 41.7 0.0 2.6 2 1 0 2 2 2 1 Microtubule binding FHA PF00498.26 KXS21962.1 - 6.3e-05 23.2 0.0 0.00016 22.0 0.0 1.7 1 0 0 1 1 1 1 FHA domain DUF4407 PF14362.6 KXS21962.1 - 7e-05 22.3 17.6 0.0069 15.8 4.1 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4407) Kinesin_assoc PF16183.5 KXS21962.1 - 0.00013 22.2 23.9 0.0095 16.1 1.7 5.2 3 2 0 4 4 4 2 Kinesin-associated HALZ PF02183.18 KXS21962.1 - 0.0031 17.7 1.9 0.0031 17.7 1.9 3.0 3 0 0 3 3 3 1 Homeobox associated leucine zipper DivIC PF04977.15 KXS21962.1 - 0.014 15.1 0.3 0.014 15.1 0.3 4.5 5 0 0 5 5 5 0 Septum formation initiator Yop-YscD_cpl PF16697.5 KXS21962.1 - 0.12 12.7 0.0 0.44 10.9 0.0 2.0 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain GHMP_kinases_C PF08544.13 KXS21962.1 - 0.12 12.7 0.1 4.1 7.8 0.0 3.0 3 0 0 3 3 2 0 GHMP kinases C terminal FUSC PF04632.12 KXS21962.1 - 0.61 8.6 7.3 0.073 11.6 2.0 1.8 2 0 0 2 2 2 0 Fusaric acid resistance protein family SlyX PF04102.12 KXS21962.1 - 0.67 10.6 11.7 1.6 9.4 1.3 4.5 4 0 0 4 4 4 0 SlyX SH3_9 PF14604.6 KXS21963.1 - 1.1e-06 28.4 0.0 2.5e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXS21963.1 - 3e-05 23.5 0.3 0.00022 20.8 0.0 2.2 2 0 0 2 2 2 1 SH3 domain TMEM154 PF15102.6 KXS21963.1 - 0.29 11.0 0.9 0.76 9.7 0.9 1.6 1 0 0 1 1 1 0 TMEM154 protein family FSA_C PF10479.9 KXS21963.1 - 4.7 5.2 10.4 9.2 4.3 10.4 1.4 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Phage_Coat_B PF05356.11 KXS21963.1 - 7.1 6.6 8.1 26 4.8 8.1 2.1 1 1 0 1 1 1 0 Phage Coat protein B SH3_1 PF00018.28 KXS21965.1 - 6e-06 25.8 0.0 9.1e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KXS21965.1 - 0.00022 21.0 0.0 0.00043 20.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Acyl-CoA_dh_1 PF00441.24 KXS21966.1 - 4.4e-09 36.7 0.1 5.7e-05 23.4 0.0 2.2 1 1 1 2 2 2 2 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KXS21966.1 - 0.029 14.6 0.1 0.054 13.7 0.1 1.6 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, middle domain AAA_lid_3 PF17862.1 KXS21968.1 - 0.12 12.2 0.0 0.28 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA+ lid domain Glycos_transf_1 PF00534.20 KXS21971.1 - 2.6e-17 62.9 0.0 4.5e-17 62.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KXS21971.1 - 7.3e-15 55.6 0.0 1.3e-14 54.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF3492 PF11997.8 KXS21971.1 - 1.4e-13 51.2 0.0 3.5e-13 49.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3492) 4HB_MCP_1 PF12729.7 KXS21972.1 - 0.35 10.4 2.2 1.9 8.0 0.1 2.3 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction DUF4491 PF14898.6 KXS21972.1 - 0.97 9.9 4.6 0.97 9.9 1.4 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4491) DUF2070 PF09843.9 KXS21975.1 - 1.6 6.9 3.5 3.4 5.9 3.5 1.6 1 1 0 1 1 1 0 Predicted membrane protein (DUF2070) ASH PF15780.5 KXS21977.1 - 2.5e-33 114.2 19.1 4.4e-06 26.8 0.1 17.6 20 0 0 20 20 20 7 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin TMEM131_like PF12371.8 KXS21977.1 - 2.4e-11 43.7 9.6 4.2 7.7 0.4 9.5 8 0 0 8 8 8 5 Transmembrane protein 131-like PapD-like PF14874.6 KXS21977.1 - 8.2e-09 35.5 9.4 0.066 13.4 0.1 9.7 10 0 0 10 10 10 1 Flagellar-associated PapD-like Motile_Sperm PF00635.26 KXS21977.1 - 2.5e-07 30.5 0.1 5.7 6.8 0.0 7.4 6 1 0 6 6 6 2 MSP (Major sperm protein) domain fn3_5 PF06280.12 KXS21977.1 - 0.00045 20.9 6.1 8 7.2 0.0 7.1 7 0 0 7 7 7 1 Fn3-like domain MYCBPAP PF14646.6 KXS21977.1 - 0.012 14.5 0.0 12 4.7 0.0 3.8 4 0 0 4 4 4 0 MYCBP-associated protein family DUF220 PF02713.14 KXS21977.1 - 0.022 14.9 0.1 0.065 13.3 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function DUF220 Pkinase PF00069.25 KXS21978.1 - 4.5e-10 39.3 0.0 5.1e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS21978.1 - 2.6e-09 36.7 0.0 3.3e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXS21978.1 - 0.0063 16.5 0.0 0.012 15.5 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KXS21978.1 - 0.14 11.7 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Sel1 PF08238.12 KXS21979.1 - 1.3e-21 76.6 15.0 9.3e-06 26.2 0.1 7.0 6 0 0 6 6 6 4 Sel1 repeat LRR_6 PF13516.6 KXS21979.1 - 5.4e-19 66.6 14.7 0.0049 16.8 0.0 7.8 8 0 0 8 8 8 5 Leucine Rich repeat LRR_4 PF12799.7 KXS21979.1 - 1.8e-09 37.7 15.9 0.008 16.6 0.4 6.8 4 2 2 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXS21979.1 - 2.2e-07 30.5 24.5 0.27 11.0 6.1 6.8 3 3 3 6 6 6 6 Leucine rich repeat LRR_1 PF00560.33 KXS21979.1 - 8.1e-06 25.7 4.7 4.3 8.3 0.2 6.5 6 0 0 6 6 6 1 Leucine Rich Repeat TPR_2 PF07719.17 KXS21979.1 - 0.0017 18.3 3.7 0.028 14.5 0.0 4.4 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 KXS21979.1 - 0.018 15.5 2.9 1 9.9 0.5 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 KXS21979.1 - 0.033 14.8 5.2 0.18 12.5 0.2 3.9 3 2 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 KXS21979.1 - 0.1 12.5 0.0 0.1 12.5 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 KXS21979.1 - 0.13 12.2 1.1 0.67 9.9 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 KXS21979.1 - 0.37 11.1 4.4 0.84 10.0 0.0 3.6 4 0 0 4 4 3 0 Tetratricopeptide repeat cNMP_binding PF00027.29 KXS21982.1 - 3.2e-11 43.1 0.1 1.8e-06 27.9 0.0 4.2 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain adh_short_C2 PF13561.6 KXS21983.1 - 7e-62 209.0 1.2 9.1e-62 208.7 1.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXS21983.1 - 1.2e-56 191.3 0.9 1.5e-56 191.0 0.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXS21983.1 - 7.3e-09 35.8 0.1 1e-08 35.3 0.1 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KXS21983.1 - 0.0023 17.9 0.8 0.0046 16.8 0.8 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_25 PF13649.6 KXS21983.1 - 0.012 16.4 0.6 0.085 13.6 0.1 2.2 1 1 1 2 2 2 0 Methyltransferase domain VHS PF00790.19 KXS21984.1 - 0.00092 19.1 0.1 0.0014 18.4 0.1 1.3 1 0 0 1 1 1 1 VHS domain AbiEi_4 PF13338.6 KXS21985.1 - 7.1e-05 22.9 0.4 0.00014 22.0 0.4 1.4 1 0 0 1 1 1 1 Transcriptional regulator, AbiEi antitoxin Histone PF00125.24 KXS21985.1 - 0.0017 18.8 0.0 0.0019 18.5 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 KXS21985.1 - 0.0037 17.4 0.0 0.0043 17.2 0.0 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 KXS21985.1 - 0.0041 17.4 0.0 0.0057 16.9 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KXS21985.1 - 0.013 15.6 0.0 0.015 15.4 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit RAP1 PF07218.11 KXS21985.1 - 0.045 12.1 0.1 0.049 11.9 0.1 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) HTH_17 PF12728.7 KXS21985.1 - 0.049 13.8 0.1 0.079 13.2 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain TFIID_20kDa PF03847.13 KXS21985.1 - 0.098 13.2 0.0 0.13 12.8 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A DNA_alkylation PF08713.11 KXS21985.1 - 0.13 12.0 0.0 0.13 12.0 0.0 1.0 1 0 0 1 1 1 0 DNA alkylation repair enzyme DUF5455 PF17537.2 KXS21986.1 - 5.7 7.4 15.1 4 7.9 10.7 2.0 1 1 1 2 2 2 0 Family of unknown function (DUF5455) AAA PF00004.29 KXS21988.1 - 1.3e-93 310.4 0.0 2.7e-48 163.7 0.0 2.2 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KXS21988.1 - 2e-24 85.1 2.8 1e-11 44.5 0.5 2.6 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 KXS21988.1 - 2.1e-14 54.3 2.7 4.6e-05 23.9 0.0 4.5 2 2 1 3 3 3 3 AAA ATPase domain RuvB_N PF05496.12 KXS21988.1 - 1.8e-12 47.3 0.0 8e-05 22.4 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 KXS21988.1 - 6.4e-12 45.9 0.0 0.00014 22.0 0.0 2.3 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 KXS21988.1 - 1.3e-09 38.3 0.0 0.00066 19.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 KXS21988.1 - 2.2e-09 37.7 0.8 0.0048 17.2 0.0 4.1 2 2 1 3 3 3 2 AAA domain AAA_5 PF07728.14 KXS21988.1 - 2.9e-09 37.0 0.2 0.0063 16.5 0.0 3.7 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 KXS21988.1 - 2.9e-08 33.8 0.0 0.0087 16.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 KXS21988.1 - 2.4e-07 31.1 0.0 0.021 15.2 0.0 2.7 2 0 0 2 2 2 2 RNA helicase NACHT PF05729.12 KXS21988.1 - 3.7e-07 30.2 0.2 0.017 15.0 0.2 3.6 3 1 0 3 3 3 2 NACHT domain ABC_tran PF00005.27 KXS21988.1 - 6.1e-07 30.0 0.0 0.011 16.2 0.0 2.6 2 0 0 2 2 2 2 ABC transporter IstB_IS21 PF01695.17 KXS21988.1 - 7.5e-07 29.0 0.0 0.039 13.7 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein TIP49 PF06068.13 KXS21988.1 - 2.1e-06 27.2 0.0 0.021 14.0 0.0 2.4 2 0 0 2 2 2 2 TIP49 P-loop domain Mg_chelatase PF01078.21 KXS21988.1 - 3.9e-06 26.4 0.1 0.042 13.2 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Vps4_C PF09336.10 KXS21988.1 - 4e-06 26.7 0.1 0.17 11.9 0.0 2.7 2 0 0 2 2 2 2 Vps4 C terminal oligomerisation domain Sigma54_activat PF00158.26 KXS21988.1 - 5e-06 26.3 0.0 0.12 12.1 0.0 2.8 3 0 0 3 3 3 2 Sigma-54 interaction domain Rad17 PF03215.15 KXS21988.1 - 1.5e-05 25.0 0.0 0.21 11.5 0.0 2.2 2 0 0 2 2 2 2 Rad17 P-loop domain TsaE PF02367.17 KXS21988.1 - 1.8e-05 24.8 0.0 0.23 11.5 0.0 2.3 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase_2 PF01637.18 KXS21988.1 - 1.9e-05 24.7 0.0 0.092 12.6 0.0 3.1 2 2 1 3 3 3 2 ATPase domain predominantly from Archaea Zeta_toxin PF06414.12 KXS21988.1 - 2.3e-05 23.7 0.1 0.03 13.6 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin AAA_18 PF13238.6 KXS21988.1 - 2.4e-05 24.9 0.0 0.12 13.0 0.0 2.7 2 1 0 2 2 2 2 AAA domain AAA_28 PF13521.6 KXS21988.1 - 4.2e-05 23.8 0.0 0.16 12.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 KXS21988.1 - 7.2e-05 22.4 0.0 0.56 9.7 0.0 2.6 2 1 0 2 2 2 2 P-loop containing dynein motor region NB-ARC PF00931.22 KXS21988.1 - 8.1e-05 21.9 0.0 0.16 11.1 0.0 2.5 2 0 0 2 2 2 2 NB-ARC domain ATPase PF06745.13 KXS21988.1 - 0.00026 20.4 0.1 1.1 8.5 0.0 2.9 3 0 0 3 3 3 2 KaiC PhoH PF02562.16 KXS21988.1 - 0.00088 18.8 0.1 1.5 8.2 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein AAA_25 PF13481.6 KXS21988.1 - 0.0012 18.4 3.2 2.1 7.9 0.1 4.2 3 1 0 4 4 4 1 AAA domain DUF815 PF05673.13 KXS21988.1 - 0.0014 17.8 0.0 0.56 9.3 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_24 PF13479.6 KXS21988.1 - 0.003 17.3 0.0 0.48 10.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain Bac_DnaA PF00308.18 KXS21988.1 - 0.0038 17.1 0.1 2.1 8.1 0.0 2.4 2 0 0 2 2 2 1 Bacterial dnaA protein Cytidylate_kin2 PF13189.6 KXS21988.1 - 0.0051 17.0 0.0 0.69 10.0 0.0 2.3 2 0 0 2 2 2 1 Cytidylate kinase-like family AAA_17 PF13207.6 KXS21988.1 - 0.0069 16.8 0.0 1.7 9.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain PduV-EutP PF10662.9 KXS21988.1 - 0.0095 15.7 0.0 4.3 7.1 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Parvo_NS1 PF01057.17 KXS21988.1 - 0.011 14.8 0.0 1.2 8.1 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 Sigma54_activ_2 PF14532.6 KXS21988.1 - 0.012 15.7 0.0 1.7 8.8 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain CPT PF07931.12 KXS21988.1 - 0.015 15.2 0.0 0.46 10.3 0.0 2.3 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein NTPase_1 PF03266.15 KXS21988.1 - 0.017 15.0 0.1 3.9 7.4 0.0 2.8 3 0 0 3 3 2 0 NTPase Viral_helicase1 PF01443.18 KXS21988.1 - 0.025 14.3 0.0 0.78 9.4 0.0 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_3 PF07726.11 KXS21988.1 - 0.036 13.9 0.0 2.3 8.1 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 KXS21988.1 - 0.036 13.8 0.0 3.3 7.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 KXS21988.1 - 0.055 12.7 0.0 6.9 5.8 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) ATP-synt_ab PF00006.25 KXS21988.1 - 0.067 12.8 0.0 8.7 5.9 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_29 PF13555.6 KXS21988.1 - 0.11 12.2 0.0 5.3 6.9 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain SRPRB PF09439.10 KXS21988.1 - 0.13 11.6 0.0 17 4.8 0.0 2.3 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit SKI PF01202.22 KXS21988.1 - 0.18 11.9 0.0 15 5.7 0.0 2.5 2 0 0 2 2 2 0 Shikimate kinase DAP3 PF10236.9 KXS21988.1 - 0.2 10.8 0.0 9 5.4 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 TniB PF05621.11 KXS21988.1 - 0.2 11.0 0.0 24 4.3 0.0 2.7 2 1 0 2 2 2 0 Bacterial TniB protein AAA_23 PF13476.6 KXS21988.1 - 0.27 11.7 0.0 9.4 6.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain Ras PF00071.22 KXS21989.1 - 3.9e-44 150.1 0.0 4.5e-44 149.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXS21989.1 - 2.8e-27 95.3 0.0 3.8e-27 94.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXS21989.1 - 4.1e-14 52.4 0.0 5.9e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KXS21989.1 - 0.00011 22.3 0.0 0.00016 21.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KXS21989.1 - 0.00033 20.2 0.0 0.076 12.5 0.0 2.1 2 0 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KXS21989.1 - 0.0007 19.5 0.0 0.0087 16.0 0.0 2.0 2 0 0 2 2 2 1 RsgA GTPase Gtr1_RagA PF04670.12 KXS21989.1 - 0.0011 18.4 0.0 0.0013 18.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KXS21989.1 - 0.0081 15.7 0.0 0.022 14.3 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1_Xtn PF16897.5 KXS21989.1 - 0.055 13.5 0.0 0.084 12.9 0.0 1.3 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain TniB PF05621.11 KXS21989.1 - 0.075 12.4 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein MCM PF00493.23 KXS21989.1 - 0.085 11.9 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain DUF410 PF04190.13 KXS21989.1 - 0.097 12.5 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF410) FragX_IP PF05994.11 KXS21990.1 - 9.1e-140 467.3 0.0 3.7e-124 415.7 0.0 2.3 1 1 0 2 2 2 2 Cytoplasmic Fragile-X interacting family DUF1394 PF07159.12 KXS21990.1 - 3.4e-09 36.4 0.1 6.3e-09 35.5 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1394) WASH-7_N PF14745.6 KXS21990.1 - 0.0014 17.2 0.0 0.0038 15.8 0.0 1.6 1 0 0 1 1 1 1 WASH complex subunit 7, N-terminal bPH_6 PF10756.9 KXS21990.1 - 0.13 12.3 0.0 0.36 10.9 0.0 1.8 1 0 0 1 1 1 0 Bacterial PH domain Vac14_Fig4_bd PF11916.8 KXS21992.1 - 5.4e-78 260.7 3.6 9e-78 260.0 3.6 1.4 1 0 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 KXS21992.1 - 4.2e-45 152.3 0.0 1.7e-41 140.7 0.0 3.7 3 0 0 3 3 3 1 Vacuolar 14 Fab1-binding region HEAT PF02985.22 KXS21992.1 - 3.2e-15 54.9 0.1 0.00066 19.7 0.0 6.6 5 0 0 5 5 5 2 HEAT repeat Cnd1 PF12717.7 KXS21992.1 - 2.2e-09 37.6 2.7 0.94 9.5 0.2 4.8 5 0 0 5 5 5 4 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 KXS21992.1 - 2.2e-09 37.6 3.4 0.013 16.0 0.0 6.7 7 1 1 8 8 8 2 HEAT-like repeat HEAT_2 PF13646.6 KXS21992.1 - 1.1e-07 32.1 7.9 0.13 12.7 0.0 5.6 6 1 1 7 7 7 3 HEAT repeats ParcG PF10274.9 KXS21992.1 - 1e-05 25.7 1.0 0.00057 20.1 0.2 3.6 3 2 1 5 5 5 1 Parkin co-regulated protein RasGEF_N_2 PF14663.6 KXS21992.1 - 2.1e-05 24.9 1.3 1.1 9.7 0.0 4.6 5 0 0 5 5 5 2 Rapamycin-insensitive companion of mTOR RasGEF_N domain MMS19_C PF12460.8 KXS21992.1 - 0.00073 18.8 0.2 0.71 8.9 0.0 3.4 3 0 0 3 3 3 1 RNAPII transcription regulator C-terminal Arm PF00514.23 KXS21992.1 - 0.016 15.3 1.2 16 5.7 0.0 4.6 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat RTP1_C1 PF10363.9 KXS21992.1 - 0.018 15.2 1.3 18 5.6 0.0 4.4 4 2 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 Tti2 PF10521.9 KXS21992.1 - 0.02 14.4 0.9 3 7.3 0.0 3.9 3 2 0 3 3 3 0 Tti2 family AAA_6 PF12774.7 KXS21993.1 - 1.6e-162 540.0 0.0 1.4e-161 537.0 0.0 2.7 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N1 PF08385.12 KXS21993.1 - 2.5e-161 538.1 7.3 2.5e-161 538.1 7.3 3.2 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 KXS21993.1 - 1.4e-126 422.8 8.7 1.4e-126 422.8 8.7 5.0 7 0 0 7 7 6 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 KXS21993.1 - 3.3e-97 324.9 0.1 2.1e-96 322.2 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 KXS21993.1 - 8.5e-84 280.1 0.9 2.5e-82 275.3 0.8 3.1 2 0 0 2 2 2 1 ATP-binding dynein motor region Dynein_C PF18199.1 KXS21993.1 - 8e-82 274.9 0.0 3.4e-81 272.8 0.0 2.2 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_7 PF12775.7 KXS21993.1 - 8.6e-76 253.5 0.5 1.5e-69 233.2 0.0 3.8 3 0 0 3 3 3 2 P-loop containing dynein motor region MT PF12777.7 KXS21993.1 - 4e-60 203.7 12.5 7.2e-60 202.8 12.5 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_lid_11 PF18198.1 KXS21993.1 - 2.9e-52 176.8 0.1 8.7e-52 175.2 0.1 1.9 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 KXS21993.1 - 7e-43 145.5 0.0 1.5e-41 141.2 0.0 3.1 3 0 0 3 3 2 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 KXS21993.1 - 1.8e-27 96.0 0.2 2.1e-08 34.3 0.0 5.2 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 KXS21993.1 - 2.8e-22 79.2 0.0 2.5e-21 76.1 0.0 2.9 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 KXS21993.1 - 1.8e-18 66.6 0.7 1.2e-17 64.0 0.1 2.9 2 0 0 2 2 2 1 AAA+ lid domain AAA PF00004.29 KXS21993.1 - 1.3e-07 32.1 0.3 0.55 10.7 0.0 5.3 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KXS21993.1 - 1.1e-06 28.9 2.8 0.19 12.0 0.0 6.0 5 0 0 5 5 4 2 AAA domain AAA_18 PF13238.6 KXS21993.1 - 0.00016 22.2 0.5 3.3 8.2 0.0 4.4 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.6 KXS21993.1 - 0.00067 20.1 11.8 0.18 12.2 0.0 6.5 7 0 0 7 7 5 1 AAA ATPase domain Rad17 PF03215.15 KXS21993.1 - 0.0076 16.2 0.1 4.8 7.0 0.0 3.4 3 0 0 3 3 3 1 Rad17 P-loop domain AAA_30 PF13604.6 KXS21993.1 - 0.013 15.2 5.3 0.45 10.2 0.0 3.3 4 0 0 4 4 3 0 AAA domain AAA_33 PF13671.6 KXS21993.1 - 0.014 15.6 0.1 5.8 7.1 0.0 3.8 3 0 0 3 3 3 0 AAA domain RsgA_GTPase PF03193.16 KXS21993.1 - 0.048 13.6 0.8 0.36 10.7 0.0 2.8 3 0 0 3 3 2 0 RsgA GTPase PhoH PF02562.16 KXS21993.1 - 0.057 12.9 1.2 0.86 9.0 0.0 3.3 3 0 0 3 3 3 0 PhoH-like protein RNA_helicase PF00910.22 KXS21993.1 - 0.084 13.3 0.1 26 5.3 0.0 3.5 3 0 0 3 3 2 0 RNA helicase LPD14 PF18827.1 KXS21993.1 - 0.1 12.9 0.0 4.8 7.4 0.1 3.4 3 0 0 3 3 2 0 Large polyvalent protein-associated domain 14 DUF4407 PF14362.6 KXS21993.1 - 0.8 9.0 19.0 2.1 7.6 6.1 4.8 5 0 0 5 5 5 0 Domain of unknown function (DUF4407) SesA PF17107.5 KXS21993.1 - 6 7.1 11.6 4.6 7.4 0.0 4.5 3 0 0 3 3 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF745 PF05335.13 KXS21993.1 - 7.3 6.3 19.4 0.26 11.0 1.4 3.5 2 0 0 2 2 2 0 Protein of unknown function (DUF745) DUF853 PF05872.12 KXS21993.1 - 7.7 5.0 7.8 3.6 6.1 0.1 3.2 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF853) AAA_28 PF13521.6 KXS21993.1 - 8.7 6.6 6.0 21 5.3 0.0 3.1 3 0 0 3 3 2 0 AAA domain Pyr_redox_2 PF07992.14 KXS21994.1 - 2.3e-22 79.6 0.1 2.8e-22 79.3 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXS21994.1 - 8.7e-14 51.8 1.3 3.1e-06 27.7 0.0 3.1 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXS21994.1 - 1.2e-10 41.2 0.7 3.9e-09 36.2 0.1 2.0 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXS21994.1 - 3.6e-10 39.5 0.2 0.00025 20.3 0.0 2.8 1 1 2 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KXS21994.1 - 3.9e-10 39.9 1.0 0.0013 18.4 0.0 3.0 2 1 1 3 3 3 3 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KXS21994.1 - 8.6e-06 24.9 0.4 7.6e-05 21.7 0.0 2.1 2 0 0 2 2 2 1 Tryptophan halogenase NAD_binding_9 PF13454.6 KXS21994.1 - 6e-05 23.1 1.9 0.14 12.1 0.0 3.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KXS21994.1 - 0.00023 20.3 0.1 0.013 14.6 0.0 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein HI0933_like PF03486.14 KXS21994.1 - 0.00088 18.1 0.2 3.3 6.3 0.0 3.0 3 0 0 3 3 3 1 HI0933-like protein NAD_binding_8 PF13450.6 KXS21994.1 - 0.0012 19.1 0.3 0.061 13.6 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.6 KXS21994.1 - 0.0024 18.3 0.2 1.7 9.2 0.1 2.4 2 1 0 2 2 2 2 Putative NAD(P)-binding Sacchrp_dh_NADP PF03435.18 KXS21994.1 - 0.0067 16.7 0.1 3.9 7.7 0.0 2.4 2 0 0 2 2 2 2 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 KXS21994.1 - 0.013 15.8 0.2 0.83 9.9 0.0 2.4 2 0 0 2 2 2 0 TrkA-N domain Thi4 PF01946.17 KXS21994.1 - 0.019 14.2 0.5 0.48 9.6 0.1 2.3 2 1 0 2 2 2 0 Thi4 family AlaDh_PNT_C PF01262.21 KXS21994.1 - 0.054 12.8 1.0 1.2 8.4 0.0 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.16 KXS21994.1 - 0.071 12.8 0.9 2.5 7.7 0.0 2.8 2 1 0 2 2 2 0 Ketopantoate reductase PanE/ApbA GIDA PF01134.22 KXS21994.1 - 0.073 12.1 7.2 0.41 9.7 0.0 2.9 2 1 1 3 3 3 0 Glucose inhibited division protein A ThiF PF00899.21 KXS21994.1 - 0.097 12.0 0.2 1.4 8.3 0.0 2.2 2 0 0 2 2 2 0 ThiF family FAD_binding_3 PF01494.19 KXS21994.1 - 0.3 10.3 1.8 0.8 8.9 0.1 2.1 2 0 0 2 2 2 0 FAD binding domain Shikimate_DH PF01488.20 KXS21994.1 - 0.36 10.9 1.4 22 5.1 0.1 2.8 3 1 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase AA_permease_2 PF13520.6 KXS21995.1 - 1.7e-34 119.4 20.7 2.2e-34 119.0 20.7 1.1 1 0 0 1 1 1 1 Amino acid permease TFIIS_C PF01096.18 KXS21996.1 - 1.1e-13 50.8 7.7 1.8e-12 46.9 3.1 2.2 2 0 0 2 2 2 2 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 KXS21996.1 - 1.6e-05 24.7 0.2 1.6e-05 24.7 0.2 2.8 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit zf-C4pol PF14260.6 KXS21996.1 - 0.0062 17.0 4.4 0.48 10.9 4.4 2.5 1 1 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta Ogr_Delta PF04606.12 KXS21996.1 - 0.015 15.2 5.3 0.06 13.3 2.0 2.3 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger Rubredoxin_2 PF18073.1 KXS21996.1 - 0.033 13.9 2.9 2.9 7.7 0.2 2.5 2 0 0 2 2 2 0 Rubredoxin metal binding domain Zn_Tnp_IS1595 PF12760.7 KXS21996.1 - 0.036 14.0 5.7 1.1 9.3 2.6 2.2 2 0 0 2 2 2 0 Transposase zinc-ribbon domain UPF0547 PF10571.9 KXS21996.1 - 0.039 14.0 4.2 3 8.0 0.0 3.1 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 zinc_ribbon_10 PF10058.9 KXS21996.1 - 0.057 13.2 3.2 3.7 7.3 0.1 2.4 2 1 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein MCM_OB PF17207.3 KXS21996.1 - 0.21 11.5 1.9 1.9 8.3 1.9 2.0 1 1 0 1 1 1 0 MCM OB domain zinc_ribbon_13 PF09855.9 KXS21996.1 - 0.23 11.7 2.7 6.2 7.1 0.9 2.4 2 1 0 2 2 2 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) YecR PF13992.6 KXS21996.1 - 0.26 11.6 3.0 0.28 11.5 2.0 1.7 1 1 0 1 1 1 0 YecR-like lipoprotein PhnA_Zn_Ribbon PF08274.12 KXS21996.1 - 0.78 9.8 4.2 3 7.9 0.0 2.7 3 0 0 3 3 3 0 PhnA Zinc-Ribbon Zn_Tnp_IS91 PF14319.6 KXS21996.1 - 1.8 8.7 8.5 0.81 9.8 0.2 2.9 1 1 2 3 3 3 0 Transposase zinc-binding domain SR1P PF13790.6 KXS21996.1 - 5.7 7.1 7.1 48 4.2 0.1 3.1 3 0 0 3 3 3 0 SR1 protein Peptidase_M17 PF00883.21 KXS21997.1 - 9.2e-40 136.8 0.0 1e-39 136.7 0.0 1.0 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Usp PF00582.26 KXS21998.1 - 1.2e-24 87.5 1.0 1.6e-11 44.9 0.2 2.1 2 0 0 2 2 2 2 Universal stress protein family HMG_box PF00505.19 KXS21999.1 - 4.7e-21 75.0 2.8 1.6e-11 44.4 0.1 3.2 2 1 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 KXS21999.1 - 3.6e-16 59.5 1.4 4.3e-12 46.5 0.1 3.0 3 0 0 3 3 3 2 HMG-box domain MlaC PF05494.12 KXS21999.1 - 0.014 15.2 2.0 0.18 11.6 0.2 2.5 2 0 0 2 2 2 0 MlaC protein PilJ PF13675.6 KXS21999.1 - 0.036 14.1 0.9 0.12 12.4 0.1 2.3 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Trypsin PF00089.26 KXS22001.1 - 1.9e-26 93.2 0.4 2.5e-26 92.8 0.4 1.2 1 0 0 1 1 1 1 Trypsin Peptidase_C37 PF05416.12 KXS22001.1 - 0.13 10.8 0.4 0.2 10.2 0.4 1.1 1 0 0 1 1 1 0 Southampton virus-type processing peptidase MOSC PF03473.17 KXS22002.1 - 1.5e-29 102.7 0.0 2e-29 102.2 0.0 1.2 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 KXS22002.1 - 3.4e-21 75.3 0.0 7.7e-21 74.2 0.0 1.6 2 0 0 2 2 2 1 MOSC N-terminal beta barrel domain RsfS PF02410.15 KXS22002.1 - 0.16 12.4 0.0 0.33 11.4 0.0 1.6 1 0 0 1 1 1 0 Ribosomal silencing factor during starvation ECH_1 PF00378.20 KXS22003.1 - 6.3e-26 91.2 0.0 7.9e-26 90.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXS22003.1 - 6.2e-21 75.2 0.2 7e-21 75.1 0.2 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase MspA PF09203.11 KXS22003.1 - 0.082 12.8 0.1 0.12 12.2 0.1 1.2 1 0 0 1 1 1 0 MspA Trehalase PF01204.18 KXS22004.1 - 6.1e-153 510.3 6.9 3.8e-91 306.4 0.1 2.3 2 0 0 2 2 2 2 Trehalase Trehalase_Ca-bi PF07492.11 KXS22004.1 - 1.5e-14 53.4 0.1 2.6e-14 52.6 0.1 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain ketoacyl-synt PF00109.26 KXS22005.1 - 6.1e-57 193.1 0.4 3.3e-55 187.4 0.0 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KXS22005.1 - 1.5e-35 121.7 0.6 2.4e-35 121.1 0.6 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KXS22005.1 - 2.3e-07 31.2 0.1 6e-07 29.9 0.0 1.6 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 KXS22005.1 - 2.1e-06 27.3 0.7 4.1e-05 23.1 0.2 2.2 2 0 0 2 2 2 1 Thiolase, N-terminal domain ACP_syn_III PF08545.10 KXS22005.1 - 0.046 13.6 3.6 0.56 10.1 3.6 2.3 1 1 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DUF647 PF04884.14 KXS22006.1 - 3.3e-63 213.5 0.5 4.5e-63 213.1 0.5 1.1 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis IQ PF00612.27 KXS22007.1 - 1.4e-07 30.6 13.3 0.00061 19.4 0.6 3.9 3 0 0 3 3 3 3 IQ calmodulin-binding motif WD40 PF00400.32 KXS22009.1 - 6.3e-38 128.1 9.5 1.8e-07 31.7 0.0 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXS22009.1 - 1.5e-19 70.1 0.0 3.7e-07 30.4 0.0 6.0 2 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KXS22009.1 - 3.9e-13 49.1 0.1 0.006 15.6 0.0 4.1 3 1 1 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KXS22009.1 - 2.9e-07 30.6 0.0 0.014 15.3 0.0 2.6 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A CSTF1_dimer PF16699.5 KXS22009.1 - 2.1e-05 24.2 0.1 3.8e-05 23.4 0.1 1.3 1 0 0 1 1 1 1 Cleavage stimulation factor subunit 1, dimerisation domain Cytochrom_D1 PF02239.16 KXS22009.1 - 0.00018 20.1 0.5 0.00051 18.7 0.1 1.8 2 1 0 2 2 2 1 Cytochrome D1 heme domain PQQ PF01011.21 KXS22009.1 - 0.00087 19.1 1.1 0.3 11.1 0.2 3.4 3 0 0 3 3 3 1 PQQ enzyme repeat WD40_like PF17005.5 KXS22009.1 - 0.0035 16.7 0.0 11 5.2 0.0 3.1 3 0 0 3 3 3 1 WD40-like domain VID27 PF08553.10 KXS22009.1 - 0.015 14.3 0.0 0.038 13.0 0.0 1.6 2 0 0 2 2 2 0 VID27 C-terminal WD40-like domain EF-hand_1 PF00036.32 KXS22009.1 - 0.17 11.5 0.6 0.71 9.6 0.0 2.1 2 0 0 2 2 2 0 EF hand PQQ_3 PF13570.6 KXS22009.1 - 2.5 8.7 7.9 42 4.8 0.0 5.4 6 0 0 6 6 6 0 PQQ-like domain ACPS PF01648.20 KXS22010.1 - 2.9e-12 46.7 0.0 6e-12 45.7 0.0 1.6 1 1 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily MDM10 PF12519.8 KXS22011.1 - 1.3e-35 123.2 8.1 1.7e-20 73.4 7.1 2.5 2 1 0 2 2 2 2 Mitochondrial distribution and morphology protein 10 Porin_3 PF01459.22 KXS22011.1 - 0.021 14.3 0.0 1.2 8.5 0.0 2.2 2 0 0 2 2 2 0 Eukaryotic porin Ion_trans PF00520.31 KXS22012.1 - 9.5e-42 142.9 12.8 1.2e-41 142.5 12.8 1.1 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 KXS22012.1 - 1.7e-06 27.0 8.0 1.7e-06 27.0 3.0 2.2 1 1 1 2 2 2 2 Polycystin cation channel Helicase_C_2 PF13307.6 KXS22013.1 - 1.7e-52 178.1 0.0 3.7e-52 177.0 0.0 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 KXS22013.1 - 6.9e-44 149.5 0.1 4.3e-43 147.0 0.1 2.1 1 1 0 1 1 1 1 DEAD_2 ResIII PF04851.15 KXS22013.1 - 1.5e-05 25.1 0.0 0.003 17.6 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KXS22013.1 - 0.0017 18.2 0.0 0.033 14.0 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KXS22013.1 - 0.0063 16.8 0.0 0.73 10.1 0.0 3.0 2 0 0 2 2 2 1 AAA domain PhoH PF02562.16 KXS22013.1 - 0.065 12.7 0.0 8.7 5.7 0.0 2.9 3 0 0 3 3 3 0 PhoH-like protein Ank PF00023.30 KXS22014.1 - 3.4e-05 24.1 2.0 0.00023 21.5 0.1 3.0 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 KXS22014.1 - 0.0053 17.0 0.9 0.13 12.6 0.0 3.0 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXS22014.1 - 0.0067 17.0 0.8 19 6.0 0.0 4.0 3 1 1 4 4 4 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXS22014.1 - 0.019 15.5 0.9 0.16 12.6 0.0 2.9 3 0 0 3 3 3 0 Ankyrin repeat Ank_2 PF12796.7 KXS22014.1 - 0.02 15.5 0.0 0.91 10.2 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) HD_4 PF13328.6 KXS22015.1 - 3.5e-21 75.6 0.1 4.9e-21 75.1 0.1 1.2 1 0 0 1 1 1 1 HD domain HD PF01966.22 KXS22015.1 - 0.0008 19.6 0.2 0.0033 17.6 0.2 1.9 1 1 0 1 1 1 1 HD domain Glyco_hydro_18 PF00704.28 KXS22016.1 - 0.00037 20.3 0.0 0.00049 19.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 L27 PF02828.16 KXS22016.1 - 0.032 14.0 0.2 0.079 12.7 0.2 1.6 1 0 0 1 1 1 0 L27 domain DUF1126 PF06565.12 KXS22017.1 - 1.9e-101 333.0 2.3 4.1e-34 116.6 0.1 3.2 3 0 0 3 3 3 3 DUF1126 PH-like domain Swi3 PF07962.12 KXS22017.1 - 0.0083 16.1 0.0 6 6.9 0.0 2.6 2 0 0 2 2 2 2 Replication Fork Protection Component Swi3 Prefoldin_2 PF01920.20 KXS22021.1 - 5e-15 55.4 1.7 5.4e-15 55.2 1.7 1.0 1 0 0 1 1 1 1 Prefoldin subunit FA_hydroxylase PF04116.13 KXS22022.1 - 4.2e-22 78.9 25.3 4.2e-22 78.9 25.3 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily MIF4G PF02854.19 KXS22023.1 - 4.7e-47 160.4 0.0 6.8e-27 94.5 0.0 3.5 3 1 0 3 3 3 3 MIF4G domain Upf2 PF04050.14 KXS22023.1 - 1.7e-23 83.8 5.4 1.7e-23 83.8 5.4 3.4 3 0 0 3 3 3 1 Up-frameshift suppressor 2 DUF599 PF04654.12 KXS22024.1 - 9.6e-44 149.3 12.5 1.3e-43 148.9 12.5 1.1 1 0 0 1 1 1 1 Protein of unknown function, DUF599 Borrelia_P13 PF05628.12 KXS22024.1 - 0.052 13.5 0.5 0.11 12.4 0.4 1.6 1 1 0 1 1 1 0 Borrelia membrane protein P13 Transpeptidase PF00905.22 KXS22024.1 - 0.076 12.2 0.0 0.096 11.9 0.0 1.1 1 0 0 1 1 1 0 Penicillin binding protein transpeptidase domain Fungal_trans PF04082.18 KXS22026.1 - 0.00018 20.6 0.3 0.00024 20.3 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain p450 PF00067.22 KXS22027.1 - 4.3e-55 187.3 0.0 1.8e-54 185.2 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KXS22028.1 - 1.7e-10 40.3 0.0 5.2e-10 38.7 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 PEX11 PF05648.14 KXS22029.1 - 4.1e-24 85.3 0.0 4.8e-24 85.1 0.0 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) SLC35F PF06027.12 KXS22029.1 - 0.11 12.0 0.1 0.17 11.3 0.1 1.2 1 0 0 1 1 1 0 Solute carrier family 35 Prefoldin_2 PF01920.20 KXS22030.1 - 9.5e-19 67.3 0.7 1.1e-18 67.1 0.7 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.17 KXS22030.1 - 0.0045 16.9 1.3 0.38 10.7 0.0 2.1 1 1 1 2 2 2 1 Prefoldin subunit FbpA PF05833.11 KXS22030.1 - 0.013 14.3 2.6 0.013 14.3 2.6 1.4 1 1 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) THP2 PF09432.10 KXS22030.1 - 0.016 15.3 2.2 0.12 12.4 2.2 2.0 1 1 0 1 1 1 0 Tho complex subunit THP2 DUF4337 PF14235.6 KXS22030.1 - 0.089 12.9 2.8 0.76 9.9 0.7 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) DivIC PF04977.15 KXS22030.1 - 0.17 11.7 4.0 2.4 8.0 1.4 2.3 2 0 0 2 2 2 0 Septum formation initiator DUF465 PF04325.13 KXS22030.1 - 0.26 11.4 0.2 0.26 11.4 0.2 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF465) CorA PF01544.18 KXS22030.1 - 0.26 10.5 2.2 12 5.0 0.6 2.1 1 1 0 2 2 2 0 CorA-like Mg2+ transporter protein Spc24 PF08286.11 KXS22030.1 - 1.4 9.2 6.3 25 5.2 0.0 2.2 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DER1 PF04511.15 KXS22031.1 - 8.2e-50 169.4 5.7 9.5e-50 169.2 5.7 1.0 1 0 0 1 1 1 1 Der1-like family Rhomboid PF01694.22 KXS22031.1 - 0.055 13.5 5.0 0.14 12.1 5.0 1.7 1 0 0 1 1 1 0 Rhomboid family GDI PF00996.18 KXS22032.1 - 8.6e-221 733.0 0.3 1e-220 732.8 0.3 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor Amino_oxidase PF01593.24 KXS22032.1 - 0.0022 17.4 0.0 0.0029 16.9 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Ribosomal_L22 PF00237.19 KXS22033.1 - 9.3e-06 25.8 0.0 4.3e-05 23.7 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L22p/L17e BRE1 PF08647.11 KXS22035.1 - 0.3 11.2 9.9 9.4 6.4 0.1 2.9 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase PAXX PF15384.6 KXS22035.1 - 0.58 9.8 4.2 0.76 9.4 1.7 2.2 2 0 0 2 2 2 0 PAXX, PAralog of XRCC4 and XLF, also called C9orf142 GAS PF13851.6 KXS22035.1 - 0.96 8.8 13.9 0.073 12.4 3.6 3.3 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding SOGA PF11365.8 KXS22035.1 - 4.5 8.5 13.4 5.7 8.1 0.1 4.1 4 0 0 4 4 4 0 Protein SOGA Fez1 PF06818.15 KXS22035.1 - 5.7 7.3 20.1 2.7 8.4 13.2 2.9 3 0 0 3 3 3 0 Fez1 zf-RING_2 PF13639.6 KXS22036.1 - 1.6e-07 31.5 6.5 1.6e-07 31.5 6.5 3.3 3 2 0 3 3 2 1 Ring finger domain zf-C3HC4 PF00097.25 KXS22036.1 - 5.2e-07 29.4 3.3 5.2e-07 29.4 3.3 3.1 3 2 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXS22036.1 - 1.2e-05 25.2 5.3 1.2e-05 25.2 5.3 2.9 3 0 0 3 3 3 1 zinc-RING finger domain zf_CCCH_4 PF18345.1 KXS22036.1 - 0.0001 22.2 9.0 0.034 14.2 1.8 3.4 2 1 0 2 2 2 2 Zinc finger domain zf-CCCH PF00642.24 KXS22036.1 - 0.00019 21.2 12.2 0.001 18.9 4.4 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KXS22036.1 - 0.00021 21.0 10.1 0.0062 16.3 3.4 2.7 2 0 0 2 2 2 2 CCCH-type zinc finger zf-RING_UBOX PF13445.6 KXS22036.1 - 0.00025 21.0 1.7 0.00025 21.0 1.7 3.3 4 0 0 4 4 3 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KXS22036.1 - 0.00027 20.7 4.8 0.00027 20.7 4.8 2.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH_2 PF14608.6 KXS22036.1 - 0.00035 20.9 9.3 0.018 15.5 3.6 3.1 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger zf-RING_11 PF17123.5 KXS22036.1 - 0.00051 19.7 5.5 0.00051 19.7 5.5 2.9 3 0 0 3 3 3 1 RING-like zinc finger FANCL_C PF11793.8 KXS22036.1 - 0.0013 18.9 4.2 0.004 17.3 4.2 1.8 1 0 0 1 1 1 1 FANCL C-terminal domain zf-rbx1 PF12678.7 KXS22036.1 - 0.0074 16.5 7.5 0.053 13.8 7.5 2.5 1 1 0 1 1 1 1 RING-H2 zinc finger domain DUF61 PF01886.16 KXS22036.1 - 0.019 15.0 0.0 0.03 14.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF61 Prok-RING_4 PF14447.6 KXS22036.1 - 0.026 14.4 7.6 0.026 14.4 7.6 3.3 2 2 0 2 2 2 0 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KXS22036.1 - 0.034 14.2 1.0 0.034 14.2 1.0 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-CCHH PF10283.9 KXS22036.1 - 0.076 13.0 4.1 2.4 8.2 0.4 2.9 2 0 0 2 2 2 0 PBZ domain zf-C3HC4_2 PF13923.6 KXS22036.1 - 0.17 11.7 18.0 0.3 11.0 9.5 4.2 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Syndecan PF01034.20 KXS22037.1 - 0.33 10.9 0.8 0.67 9.9 0.8 1.5 1 0 0 1 1 1 0 Syndecan domain TPP_enzyme_N PF02776.18 KXS22039.1 - 1.3e-44 151.9 0.1 5.4e-44 149.8 0.1 2.1 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 KXS22039.1 - 1.8e-36 124.9 0.1 5.1e-36 123.4 0.1 1.8 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 KXS22039.1 - 2.3e-26 92.4 0.5 9.7e-26 90.4 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain CO_dh PF02552.16 KXS22039.1 - 0.00023 21.0 0.0 0.00046 20.0 0.0 1.4 1 0 0 1 1 1 1 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit NMT1_3 PF16868.5 KXS22039.1 - 0.03 13.7 0.1 0.054 12.9 0.1 1.4 1 0 0 1 1 1 0 NMT1-like family UBM PF14377.6 KXS22040.1 - 0.0073 15.7 0.4 0.015 14.7 0.4 1.6 1 0 0 1 1 1 1 Ubiquitin binding region zf-H2C2_2 PF13465.6 KXS22041.1 - 4.8e-10 39.4 6.7 0.00019 21.7 0.5 2.1 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KXS22041.1 - 3.8e-05 24.1 8.1 0.0062 17.3 0.4 3.1 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KXS22041.1 - 0.0033 17.7 4.5 0.49 10.8 0.0 3.1 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zinc_ribbon_9 PF14369.6 KXS22041.1 - 0.0064 16.7 0.2 0.58 10.5 0.1 2.1 2 0 0 2 2 2 1 zinc-ribbon TackOD1 PF18551.1 KXS22041.1 - 0.0081 15.9 1.4 0.0095 15.6 1.4 1.1 1 0 0 1 1 1 1 Thaumarchaeal output domain 1 zf-C2H2 PF00096.26 KXS22041.1 - 0.009 16.4 9.7 0.78 10.3 0.8 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type PyrI_C PF02748.15 KXS22041.1 - 0.012 15.4 0.5 0.51 10.3 0.0 2.0 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Elf1 PF05129.13 KXS22041.1 - 0.12 12.5 1.8 0.18 11.8 1.8 1.4 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like zf-met PF12874.7 KXS22041.1 - 0.12 12.8 4.4 7.7 7.1 0.0 3.1 3 0 0 3 3 3 0 Zinc-finger of C2H2 type YwqJ-deaminase PF14431.6 KXS22041.1 - 0.26 11.5 2.1 0.8 9.9 0.1 1.9 1 1 1 2 2 2 0 YwqJ-like deaminase PAP_PilO PF06864.12 KXS22043.1 - 0.0017 17.3 0.1 0.0032 16.3 0.1 1.4 1 0 0 1 1 1 1 Pilin accessory protein (PilO) SpoIIIAH PF12685.7 KXS22043.1 - 0.25 11.2 1.7 0.74 9.6 0.0 2.1 2 0 0 2 2 2 0 SpoIIIAH-like protein Pes-10 PF07149.11 KXS22043.1 - 9.8 5.1 8.1 14 4.6 8.1 1.1 1 0 0 1 1 1 0 Pes-10 PNP_UDP_1 PF01048.20 KXS22044.1 - 0.00055 19.3 0.0 0.0011 18.3 0.0 1.4 1 0 0 1 1 1 1 Phosphorylase superfamily CDC45 PF02724.14 KXS22045.1 - 1.2 7.3 4.9 1.6 6.9 4.9 1.1 1 0 0 1 1 1 0 CDC45-like protein LRR_4 PF12799.7 KXS22046.1 - 1.3e-14 54.1 25.4 1.9e-07 31.3 3.7 3.7 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXS22046.1 - 2.7e-10 39.9 12.0 3.1e-10 39.7 5.4 3.5 3 1 1 4 4 4 2 Leucine rich repeat SH3_9 PF14604.6 KXS22046.1 - 1e-06 28.5 0.0 1.8e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXS22046.1 - 0.0022 17.6 0.0 0.0036 16.9 0.0 1.4 1 0 0 1 1 1 1 SH3 domain LRR_1 PF00560.33 KXS22046.1 - 0.004 17.5 9.8 3.5 8.6 0.4 4.7 4 0 0 4 4 4 2 Leucine Rich Repeat SH3_2 PF07653.17 KXS22046.1 - 0.0068 16.1 0.0 0.018 14.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain LRR_6 PF13516.6 KXS22046.1 - 0.017 15.2 16.6 0.45 10.7 0.8 4.6 5 0 0 5 5 5 0 Leucine Rich repeat Pyr_redox_2 PF07992.14 KXS22047.1 - 6.3e-26 91.3 0.0 7.6e-26 91.0 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXS22047.1 - 8.9e-05 23.0 0.0 0.0049 17.4 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXS22047.1 - 0.00013 21.3 0.0 0.00027 20.3 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXS22047.1 - 0.00042 19.6 0.0 0.0017 17.6 0.0 1.9 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) ThiF PF00899.21 KXS22047.1 - 0.0079 15.6 0.0 0.016 14.6 0.0 1.4 1 0 0 1 1 1 1 ThiF family NAD_binding_9 PF13454.6 KXS22047.1 - 0.013 15.5 0.3 22 5.0 0.0 3.2 2 1 1 3 3 3 0 FAD-NAD(P)-binding Glyco_transf_90 PF05686.12 KXS22048.1 - 4.9e-19 68.5 0.0 2e-18 66.5 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferase family 90 DUF2232 PF09991.9 KXS22049.1 - 0.076 12.2 0.0 0.13 11.4 0.0 1.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2232) zf-C2H2_4 PF13894.6 KXS22051.1 - 8.6e-05 23.1 5.6 0.021 15.7 1.7 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 KXS22051.1 - 0.0028 18.0 0.4 0.3 11.5 0.0 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 KXS22051.1 - 0.012 16.0 5.1 0.19 12.3 1.7 2.9 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KXS22051.1 - 0.081 13.2 0.5 10 6.5 0.3 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Serglycin PF04360.12 KXS22051.1 - 1.8 8.5 10.4 1.1 9.1 6.7 2.5 2 0 0 2 2 2 0 Serglycin Herpes_capsid PF06112.11 KXS22051.1 - 5.6 7.0 29.4 34 4.5 23.9 3.4 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein UBA PF00627.31 KXS22053.1 - 0.041 13.8 0.0 0.066 13.1 0.0 1.4 1 0 0 1 1 1 0 UBA/TS-N domain CUE PF02845.16 KXS22054.1 - 0.1 12.3 0.0 0.2 11.4 0.0 1.5 2 0 0 2 2 2 0 CUE domain HHV-1_VABD PF16852.5 KXS22054.1 - 0.51 10.4 14.9 0.74 9.9 4.0 3.6 2 1 1 3 3 3 0 Herpes viral adaptor-to-host cellular mRNA binding domain bZIP_1 PF00170.21 KXS22055.1 - 3.8e-06 26.9 20.5 3.1e-05 24.0 6.7 2.7 2 1 0 2 2 2 2 bZIP transcription factor CENP-F_leu_zip PF10473.9 KXS22055.1 - 2.1e-05 24.6 18.2 0.00018 21.5 7.5 2.3 1 1 0 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 bZIP_2 PF07716.15 KXS22055.1 - 0.00054 20.0 7.4 0.00054 20.0 7.4 3.7 2 1 1 3 3 3 1 Basic region leucine zipper MGTL PF17059.5 KXS22055.1 - 0.16 11.8 0.2 0.7 9.8 0.2 2.0 1 0 0 1 1 1 0 MgtA leader peptide FlaC_arch PF05377.11 KXS22055.1 - 0.54 10.7 4.9 4 7.9 0.8 2.6 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) YabA PF06156.13 KXS22055.1 - 1.1 10.0 4.6 3 8.5 0.3 2.4 2 0 0 2 2 2 0 Initiation control protein YabA Seryl_tRNA_N PF02403.22 KXS22055.1 - 1.9 8.7 10.6 2 8.7 6.1 2.6 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain TMCO5 PF14992.6 KXS22055.1 - 5.6 6.5 6.4 4.9 6.6 1.5 2.2 2 0 0 2 2 2 0 TMCO5 family bZIP_Maf PF03131.17 KXS22055.1 - 6 7.5 18.9 2.3 8.8 7.2 2.9 1 1 0 2 2 2 0 bZIP Maf transcription factor Tho2 PF11262.8 KXS22055.1 - 9.5 5.3 5.3 3.1 6.9 2.1 1.6 1 1 1 2 2 2 0 Transcription factor/nuclear export subunit protein 2 SSF PF00474.17 KXS22056.1 - 6.7e-20 71.3 31.5 1.3e-19 70.4 31.5 1.4 1 0 0 1 1 1 1 Sodium:solute symporter family zf-RING_2 PF13639.6 KXS22057.1 - 1e-13 51.3 4.7 1.7e-13 50.7 4.7 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KXS22057.1 - 5.7e-10 38.8 1.7 1e-09 37.9 1.7 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 KXS22057.1 - 1.2e-09 38.3 2.5 2.1e-09 37.5 2.5 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KXS22057.1 - 2.9e-09 36.6 3.1 4.6e-09 36.0 3.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXS22057.1 - 3.5e-09 36.3 4.0 5.6e-09 35.7 4.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXS22057.1 - 1.4e-08 34.5 1.7 2.1e-08 34.0 1.7 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KXS22057.1 - 2.6e-07 30.5 5.3 5.3e-07 29.5 5.3 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 KXS22057.1 - 3e-06 27.2 2.9 8e-06 25.8 2.9 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 KXS22057.1 - 5.6e-06 26.1 1.9 9.8e-06 25.3 1.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KXS22057.1 - 0.00057 19.7 5.2 0.011 15.6 6.4 2.1 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 KXS22057.1 - 0.037 13.8 3.5 0.1 12.4 3.4 1.7 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Zn_ribbon_17 PF17120.5 KXS22057.1 - 0.043 13.4 1.9 0.081 12.6 1.9 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3H2C3 PF17122.5 KXS22057.1 - 0.056 13.5 0.7 0.056 13.5 0.7 1.8 2 0 0 2 2 2 0 Zinc-finger zf-C3HC4_4 PF15227.6 KXS22057.1 - 0.16 12.2 4.9 0.29 11.3 4.9 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 KXS22057.1 - 0.21 11.8 4.3 1.1 9.5 4.3 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain DUF4451 PF14616.6 KXS22057.1 - 0.25 11.5 0.2 3.9 7.7 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4451) zf-Nse PF11789.8 KXS22057.1 - 0.27 11.1 0.8 0.46 10.3 0.8 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit PHD PF00628.29 KXS22057.1 - 0.56 10.2 2.1 0.88 9.5 2.1 1.3 1 0 0 1 1 1 0 PHD-finger RINGv PF12906.7 KXS22057.1 - 0.67 10.1 3.2 1.3 9.2 3.2 1.5 1 0 0 1 1 1 0 RING-variant domain Ank_3 PF13606.6 KXS22058.1 - 2.2e-07 30.6 0.0 0.046 14.3 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 KXS22058.1 - 6.5e-06 26.6 0.0 3.2 8.4 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXS22058.1 - 7.4e-06 26.5 0.0 0.0033 18.0 0.0 2.8 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXS22058.1 - 2.9e-05 24.3 0.2 1.1 9.7 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 KXS22058.1 - 0.002 18.5 0.9 6.4 7.4 0.0 3.4 3 1 0 3 3 3 2 Ankyrin repeat Galactosyl_T PF01762.21 KXS22059.1 - 2.1e-06 27.7 0.1 7e-05 22.7 0.0 2.8 2 1 0 2 2 2 1 Galactosyltransferase Fringe PF02434.16 KXS22059.1 - 0.00055 19.5 0.0 0.0013 18.2 0.0 1.6 1 0 0 1 1 1 1 Fringe-like AAA_3 PF07726.11 KXS22059.1 - 0.12 12.3 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) dCMP_cyt_deam_1 PF00383.23 KXS22060.1 - 9.3e-16 57.6 1.1 1.1e-15 57.3 0.1 1.6 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KXS22060.1 - 2.4e-12 46.8 0.0 3.6e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 MafB19-like deaminase Inv-AAD PF18785.1 KXS22060.1 - 9.6e-05 22.2 0.0 0.00017 21.4 0.0 1.4 1 0 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase SNAD4 PF18750.1 KXS22060.1 - 0.18 11.9 0.0 0.31 11.2 0.0 1.3 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 Bd3614-deam PF14439.6 KXS22060.1 - 0.63 10.1 7.2 32 4.6 7.2 2.1 1 1 0 1 1 1 0 Bd3614-like deaminase Abhydrolase_6 PF12697.7 KXS22061.1 - 2.6e-23 83.8 1.0 3.4e-23 83.4 1.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXS22061.1 - 3.3e-13 49.9 0.1 5.1e-13 49.3 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXS22061.1 - 2.8e-09 36.6 0.0 3.9e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 KXS22061.1 - 2.6e-05 24.1 0.0 4.2e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 KXS22061.1 - 0.0015 18.7 0.0 0.0023 18.1 0.0 1.3 1 1 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.13 KXS22061.1 - 0.0019 18.0 0.0 0.0036 17.1 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_3 PF07859.13 KXS22061.1 - 0.0075 16.1 0.0 0.014 15.2 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 KXS22061.1 - 0.011 15.5 0.0 0.02 14.7 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Chlorophyllase2 PF12740.7 KXS22061.1 - 0.023 13.6 0.0 0.038 12.9 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Peptidase_S9 PF00326.21 KXS22061.1 - 0.029 13.9 0.0 0.042 13.3 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family Ser_hydrolase PF06821.13 KXS22061.1 - 0.029 14.2 0.0 0.042 13.7 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase Lipase_3 PF01764.25 KXS22061.1 - 0.085 12.7 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) DUF676 PF05057.14 KXS22061.1 - 0.11 12.1 0.1 0.18 11.3 0.1 1.5 1 0 0 1 1 1 0 Putative serine esterase (DUF676) COesterase PF00135.28 KXS22061.1 - 0.2 10.5 0.0 0.27 10.0 0.0 1.1 1 0 0 1 1 1 0 Carboxylesterase family DUF2974 PF11187.8 KXS22061.1 - 0.21 11.1 0.0 0.39 10.3 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2974) CK2S PF15011.6 KXS22062.1 - 0.14 12.0 0.1 1.9 8.4 0.0 2.6 3 0 0 3 3 3 0 Casein Kinase 2 substrate UCH PF00443.29 KXS22063.1 - 5.2e-67 226.0 0.0 6.5e-67 225.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KXS22063.1 - 1.7e-14 54.1 0.0 8.5e-14 51.9 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 KXS22063.1 - 0.011 15.3 0.0 4 6.8 0.0 2.9 3 0 0 3 3 3 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase HscB_4_cys PF18256.1 KXS22063.1 - 0.02 14.7 0.1 0.043 13.6 0.1 1.5 1 0 0 1 1 1 0 Co-chaperone HscB tetracysteine metal binding motif DAO PF01266.24 KXS22064.1 - 1e-20 74.6 0.0 2.4e-20 73.4 0.0 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXS22064.1 - 0.0037 16.5 0.0 0.0087 15.3 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXS22064.1 - 0.0039 17.7 0.7 0.0095 16.5 0.7 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KXS22064.1 - 0.0073 15.6 0.0 0.014 14.7 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 KXS22064.1 - 0.017 14.2 0.0 0.038 13.1 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain 3HCDH_N PF02737.18 KXS22064.1 - 0.052 13.4 0.0 0.089 12.7 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 KXS22064.1 - 0.09 12.1 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Mis12 PF05859.12 KXS22065.1 - 3.8e-27 95.0 0.4 6e-27 94.3 0.4 1.3 1 0 0 1 1 1 1 Mis12 protein FapA PF03961.13 KXS22065.1 - 0.18 10.4 0.1 0.3 9.6 0.1 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A SlyX PF04102.12 KXS22065.1 - 0.79 10.4 5.5 1.9 9.1 2.7 2.9 3 0 0 3 3 3 0 SlyX Med7 PF05983.11 KXS22066.1 - 2e-25 90.0 0.0 3.3e-25 89.3 0.0 1.3 1 0 0 1 1 1 1 MED7 protein Flg_hook PF02120.16 KXS22066.1 - 0.096 12.6 0.3 0.24 11.3 0.3 1.7 1 1 0 1 1 1 0 Flagellar hook-length control protein FliK Lectin_N PF03954.14 KXS22067.1 - 0.02 14.6 10.9 0.41 10.4 0.1 3.8 4 0 0 4 4 4 0 Hepatic lectin, N-terminal domain FNIP_M PF14637.6 KXS22067.1 - 0.048 13.7 0.1 0.12 12.3 0.1 1.7 1 0 0 1 1 1 0 Folliculin-interacting protein middle domain DUF641 PF04859.12 KXS22067.1 - 0.7 10.2 21.6 4.3 7.7 1.6 4.5 4 1 0 4 4 4 0 Plant protein of unknown function (DUF641) SHIPPO-rpt PF07004.12 KXS22068.1 - 5.9e-11 42.7 43.0 0.00049 20.9 0.3 7.3 7 1 0 7 7 7 4 Sperm-tail PG-rich repeat PEX11 PF05648.14 KXS22069.1 - 2e-52 177.9 4.5 2.2e-52 177.7 4.5 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) UQ_con PF00179.26 KXS22070.1 - 2.8e-42 143.7 0.0 3.5e-42 143.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 KXS22070.1 - 0.017 15.0 0.0 0.029 14.2 0.0 1.4 1 0 0 1 1 1 0 UEV domain Cpn60_TCP1 PF00118.24 KXS22071.1 - 1.7e-159 531.6 2.9 2e-159 531.4 2.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family CPT PF07931.12 KXS22071.1 - 0.062 13.1 0.1 0.34 10.8 0.1 2.2 3 0 0 3 3 3 0 Chloramphenicol phosphotransferase-like protein UDG PF03167.19 KXS22072.1 - 3.7e-14 53.0 0.0 4.9e-14 52.6 0.0 1.3 1 1 0 1 1 1 1 Uracil DNA glycosylase superfamily MFS_1 PF07690.16 KXS22073.1 - 8.9e-30 103.8 35.4 8.9e-30 103.8 35.4 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily CHD5 PF04420.14 KXS22073.1 - 0.2 11.5 3.4 7 6.5 0.2 2.4 2 0 0 2 2 2 0 CHD5-like protein zf-CHY PF05495.12 KXS22074.1 - 2.6e-09 37.4 9.2 2.6e-09 37.4 9.2 3.0 2 1 1 3 3 3 1 CHY zinc finger RWD PF05773.22 KXS22074.1 - 0.12 12.6 0.0 0.24 11.7 0.0 1.4 1 0 0 1 1 1 0 RWD domain DNA_pol_B PF00136.21 KXS22075.1 - 1.6e-121 406.2 0.0 2.6e-121 405.5 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.10 KXS22075.1 - 2.9e-50 170.6 3.5 4.7e-50 169.9 3.5 1.3 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.19 KXS22075.1 - 3.9e-42 144.6 0.0 6.9e-42 143.8 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.8 KXS22075.1 - 5.1e-20 71.3 8.7 1.9e-19 69.5 8.7 2.0 1 0 0 1 1 1 1 DNA polymerase alpha subunit p180 N terminal DNA_pol_B_2 PF03175.13 KXS22075.1 - 0.051 12.4 0.0 0.096 11.5 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral DNA_pol_B_exo2 PF10108.9 KXS22075.1 - 0.11 12.1 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB JAB PF01398.21 KXS22076.1 - 1.6e-33 115.2 0.1 2.6e-33 114.5 0.1 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease CSN5_C PF18323.1 KXS22076.1 - 5e-26 91.4 0.0 1.3e-25 90.1 0.0 1.7 1 0 0 1 1 1 1 Cop9 signalosome subunit 5 C-terminal domain Prok-JAB PF14464.6 KXS22076.1 - 0.0064 16.3 0.0 0.014 15.2 0.0 1.6 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain EF-hand_14 PF17959.1 KXS22076.1 - 0.068 13.5 0.1 9.2 6.7 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain TetR_C_19 PF17924.1 KXS22076.1 - 0.17 12.5 0.0 0.36 11.4 0.0 1.5 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain UQ_con PF00179.26 KXS22077.1 - 4.5e-13 49.1 0.0 4.8e-13 48.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KXS22077.1 - 0.079 13.3 0.0 0.079 13.3 0.0 1.2 1 0 0 1 1 1 0 RWD domain UPF0061 PF02696.14 KXS22078.1 - 9.5e-73 245.5 0.0 1.1e-71 242.0 0.0 2.0 1 1 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family zf-CCCH PF00642.24 KXS22080.1 - 5.4e-10 38.9 2.7 1e-09 38.0 2.7 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.6 KXS22080.1 - 8e-08 32.0 5.9 1.4e-07 31.2 5.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf_CCCH_4 PF18345.1 KXS22080.1 - 4e-06 26.7 4.6 8.1e-06 25.7 4.6 1.6 1 0 0 1 1 1 1 Zinc finger domain zf-C3HC4_2 PF13923.6 KXS22080.1 - 7.4e-06 25.7 10.0 1.5e-05 24.8 10.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXS22080.1 - 2e-05 24.5 9.9 3.3e-05 23.7 9.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KXS22080.1 - 9.2e-05 22.2 11.3 0.00018 21.3 11.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXS22080.1 - 0.00012 22.0 10.3 0.00025 21.0 10.3 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-CCCH_4 PF18044.1 KXS22080.1 - 0.00024 20.8 2.8 0.00024 20.8 2.8 2.2 2 0 0 2 2 2 1 CCCH-type zinc finger zf-RING_2 PF13639.6 KXS22080.1 - 0.00059 20.1 9.3 0.0012 19.1 9.3 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_10 PF16685.5 KXS22080.1 - 0.0011 19.0 5.4 0.0011 19.0 5.4 1.6 2 0 0 2 2 1 1 zinc RING finger of MSL2 zf-RanBP PF00641.18 KXS22080.1 - 0.0027 17.0 3.7 0.0027 17.0 3.7 1.9 2 0 0 2 2 1 1 Zn-finger in Ran binding protein and others zf-C3HC4_4 PF15227.6 KXS22080.1 - 0.0077 16.4 8.5 0.019 15.1 8.5 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-CCCH_2 PF14608.6 KXS22080.1 - 0.034 14.6 1.4 0.084 13.4 1.4 1.7 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger Prok-RING_4 PF14447.6 KXS22080.1 - 0.054 13.4 8.4 0.098 12.5 8.4 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Hamartin PF04388.12 KXS22080.1 - 0.12 11.1 1.6 0.14 10.8 1.6 1.1 1 0 0 1 1 1 0 Hamartin protein zf-Nse PF11789.8 KXS22080.1 - 0.14 12.0 3.6 0.25 11.2 3.6 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-FPG_IleRS PF06827.14 KXS22080.1 - 0.55 10.2 3.4 1.4 8.9 3.4 1.7 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS zf-P11 PF03854.14 KXS22080.1 - 1 9.0 5.1 1.8 8.3 5.1 1.4 1 0 0 1 1 1 0 P-11 zinc finger PHD PF00628.29 KXS22081.1 - 2.1e-10 40.3 6.1 4e-10 39.4 6.1 1.5 1 0 0 1 1 1 1 PHD-finger WHIM1 PF15612.6 KXS22081.1 - 0.00022 20.7 0.2 0.0021 17.6 0.0 2.4 2 0 0 2 2 2 1 WSTF, HB1, Itc1p, MBD9 motif 1 DDT PF02791.17 KXS22081.1 - 0.0076 16.5 0.4 0.015 15.6 0.4 1.4 1 0 0 1 1 1 1 DDT domain WSD PF15613.6 KXS22081.1 - 0.01 16.3 0.6 0.01 16.3 0.6 3.0 2 1 0 2 2 2 0 Williams-Beuren syndrome DDT (WSD), D-TOX E motif zf-CSL PF05207.13 KXS22081.1 - 0.063 13.0 4.5 0.17 11.6 4.5 1.8 1 0 0 1 1 1 0 CSL zinc finger Prok-RING_1 PF14446.6 KXS22081.1 - 0.064 13.2 1.0 0.13 12.2 1.0 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 PHD_2 PF13831.6 KXS22081.1 - 0.22 11.1 9.8 0.016 14.8 4.0 2.0 2 0 0 2 2 2 0 PHD-finger zf-CW PF07496.15 KXS22081.1 - 0.62 10.1 4.8 1.6 8.8 4.8 1.8 1 0 0 1 1 1 0 CW-type Zinc Finger C1_2 PF03107.16 KXS22081.1 - 1.1 9.6 5.8 0.22 11.8 1.8 1.9 2 0 0 2 2 2 0 C1 domain Ima1_N PF09779.9 KXS22081.1 - 1.4 9.7 5.4 1.3 9.9 0.3 2.7 1 1 1 2 2 2 0 Ima1 N-terminal domain SNAP PF14938.6 KXS22082.1 - 6.3e-28 98.0 12.2 7.7e-28 97.7 12.2 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 KXS22082.1 - 1.7e-05 25.0 9.2 0.0065 16.7 0.2 3.6 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_MalT PF17874.1 KXS22082.1 - 0.0036 16.7 2.3 0.079 12.3 0.6 1.9 1 1 1 2 2 2 2 MalT-like TPR region Glutaminase PF04960.15 KXS22082.1 - 0.027 13.7 0.5 0.036 13.3 0.5 1.2 1 0 0 1 1 1 0 Glutaminase ERp29 PF07749.12 KXS22082.1 - 0.12 13.3 2.5 4.1 8.4 0.4 3.3 2 1 1 3 3 3 0 Endoplasmic reticulum protein ERp29, C-terminal domain TPR_7 PF13176.6 KXS22082.1 - 0.14 12.2 10.1 15 5.9 0.1 5.5 3 2 2 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 KXS22082.1 - 0.42 11.6 7.4 4.6 8.3 0.4 4.1 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 KXS22082.1 - 1.3 9.0 13.4 33 4.5 0.0 6.1 5 2 2 7 7 7 0 Tetratricopeptide repeat MIT PF04212.18 KXS22082.1 - 9.6 6.4 11.6 0.35 11.0 1.5 3.2 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain F-box-like PF12937.7 KXS22083.1 - 0.0018 18.1 0.1 0.009 15.9 0.1 2.3 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.6 KXS22083.1 - 2.5 7.9 8.8 3.8 7.3 0.0 4.4 4 2 1 5 5 5 0 Leucine rich repeat Amidohydro_3 PF07969.11 KXS22084.1 - 5.3e-73 247.1 0.1 8.7e-73 246.4 0.0 1.3 2 0 0 2 2 2 1 Amidohydrolase family Amidohydro_1 PF01979.20 KXS22084.1 - 8.1e-08 32.0 0.0 0.00065 19.1 0.0 3.1 2 1 0 2 2 2 2 Amidohydrolase family SurA_N_3 PF13624.6 KXS22084.1 - 0.006 16.4 0.0 0.013 15.3 0.0 1.6 1 0 0 1 1 1 1 SurA N-terminal domain Rtf2 PF04641.12 KXS22085.1 - 3.7e-75 252.7 5.6 3.7e-75 252.7 5.6 1.6 1 1 1 2 2 2 1 Rtf2 RING-finger zf-NOSIP PF15906.5 KXS22085.1 - 0.0015 18.7 0.0 0.087 13.0 0.0 2.7 2 0 0 2 2 2 1 Zinc-finger of nitric oxide synthase-interacting protein zf-Nse PF11789.8 KXS22085.1 - 0.0067 16.2 0.0 4.6 7.1 0.2 2.5 2 0 0 2 2 2 2 Zinc-finger of the MIZ type in Nse subunit zf-RING_5 PF14634.6 KXS22085.1 - 0.028 14.4 0.4 0.062 13.3 0.4 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 KXS22085.1 - 0.029 14.4 0.0 0.11 12.6 0.0 2.1 1 1 0 1 1 1 0 RING-type zinc-finger Prok-RING_4 PF14447.6 KXS22085.1 - 0.12 12.3 0.4 0.33 10.8 0.4 1.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KXS22085.1 - 0.17 12.3 0.1 0.4 11.0 0.1 1.6 1 1 0 1 1 1 0 Ring finger domain DUF4746 PF15928.5 KXS22085.1 - 1.2 8.5 5.7 1.9 7.8 5.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) XRN_M PF17846.1 KXS22085.1 - 5.2 5.9 8.7 7.4 5.4 8.7 1.1 1 0 0 1 1 1 0 Xrn1 helical domain CDC45 PF02724.14 KXS22085.1 - 5.4 5.2 14.7 7.3 4.7 14.7 1.1 1 0 0 1 1 1 0 CDC45-like protein SR-25 PF10500.9 KXS22085.1 - 5.9 6.4 26.6 1.2 8.7 16.1 2.6 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF1840 PF08895.11 KXS22085.1 - 7.2 7.0 8.3 1.1 9.6 1.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) DUF4407 PF14362.6 KXS22085.1 - 7.5 5.8 9.1 12 5.2 9.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Presenilin PF01080.17 KXS22085.1 - 7.7 5.2 11.2 10 4.8 11.2 1.1 1 0 0 1 1 1 0 Presenilin Malic_M PF03949.15 KXS22086.1 - 6e-83 278.0 0.0 8.1e-83 277.6 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 KXS22086.1 - 1.7e-65 220.2 0.0 2.8e-65 219.5 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Mem_trans PF03547.18 KXS22087.1 - 9.8e-27 93.3 16.6 3.6e-25 88.2 16.6 2.4 1 1 0 1 1 1 1 Membrane transport protein DUF1275 PF06912.11 KXS22087.1 - 0.0012 18.8 2.5 0.0012 18.8 2.5 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF1275) DNA_pol3_delta2 PF13177.6 KXS22088.1 - 1.4e-13 50.9 0.0 3e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 KXS22088.1 - 1.8e-07 31.7 0.1 4.9e-07 30.2 0.1 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 KXS22088.1 - 0.00046 20.5 1.5 0.0026 18.1 0.0 2.6 3 0 0 3 3 3 1 Replication factor C C-terminal domain DNA_pol3_delta PF06144.13 KXS22088.1 - 0.00064 19.5 0.3 0.0013 18.5 0.3 1.5 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_16 PF13191.6 KXS22088.1 - 0.0019 18.6 0.3 0.098 13.0 0.0 2.9 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KXS22088.1 - 0.0029 17.9 0.6 0.011 16.0 0.2 2.1 2 1 0 2 2 2 1 AAA domain Rad17 PF03215.15 KXS22088.1 - 0.003 17.5 0.0 0.0074 16.2 0.0 1.7 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_assoc_2 PF16193.5 KXS22088.1 - 0.054 13.8 0.2 0.13 12.6 0.0 1.7 2 0 0 2 2 1 0 AAA C-terminal domain ABC_tran PF00005.27 KXS22088.1 - 0.058 13.9 0.0 0.12 12.9 0.0 1.5 1 0 0 1 1 1 0 ABC transporter RuvB_N PF05496.12 KXS22088.1 - 0.075 12.8 0.2 3.6 7.3 0.0 2.9 1 1 1 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 KXS22088.1 - 0.083 12.3 0.0 3.1 7.1 0.0 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI TetR_C_24 PF17932.1 KXS22088.1 - 0.34 11.2 1.4 1 9.7 0.1 2.4 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain PHD PF00628.29 KXS22089.1 - 2.6e-10 40.0 6.9 4.3e-10 39.3 6.9 1.3 1 0 0 1 1 1 1 PHD-finger PHD_3 PF13922.6 KXS22089.1 - 0.15 12.5 4.8 0.12 12.8 1.1 2.7 2 0 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx PHD_2 PF13831.6 KXS22089.1 - 0.85 9.2 4.5 1.4 8.5 4.5 1.3 1 0 0 1 1 1 0 PHD-finger ABC1 PF03109.16 KXS22091.1 - 3e-20 72.6 0.0 5.6e-19 68.5 0.0 2.2 2 0 0 2 2 2 1 ABC1 family Rad9 PF04139.13 KXS22092.1 - 3.3e-53 180.7 0.5 4.1e-53 180.4 0.5 1.1 1 0 0 1 1 1 1 Rad9 Gal-bind_lectin PF00337.22 KXS22092.1 - 0.057 12.9 0.0 9 5.8 0.1 2.5 2 1 0 2 2 2 0 Galactoside-binding lectin SIR2 PF02146.17 KXS22093.1 - 3.7e-29 101.9 0.0 6.2e-19 68.6 0.0 2.2 2 0 0 2 2 2 2 Sir2 family Pirin PF02678.16 KXS22094.1 - 2.8e-28 98.1 0.0 4.1e-28 97.5 0.0 1.2 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 KXS22094.1 - 2.2e-05 24.8 0.0 4e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Pirin C-terminal cupin domain MDM31_MDM32 PF08118.11 KXS22095.1 - 0.00085 18.1 1.8 0.001 17.8 1.8 1.1 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins GAGA_bind PF06217.12 KXS22095.1 - 0.05 13.9 7.4 0.048 13.9 7.4 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family CPSF100_C PF13299.6 KXS22095.1 - 0.17 12.1 10.4 0.23 11.6 10.4 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF5427 PF10310.9 KXS22095.1 - 0.3 10.0 15.5 0.35 9.8 15.5 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5427) CDRT4 PF15213.6 KXS22095.1 - 0.43 11.2 10.1 0.71 10.5 10.1 1.3 1 0 0 1 1 1 0 CMT1A duplicated region transcript 4 protein Neur_chan_memb PF02932.16 KXS22095.1 - 0.46 10.5 4.3 0.49 10.4 4.3 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4366 PF14283.6 KXS22095.1 - 0.78 9.8 10.7 1.2 9.1 10.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) PA26 PF04636.13 KXS22095.1 - 0.79 8.6 7.1 0.9 8.4 7.1 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DUF3915 PF13054.6 KXS22095.1 - 0.92 9.5 3.5 1.3 9.0 3.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Atrophin-1 PF03154.15 KXS22095.1 - 1.3 7.2 17.2 1.9 6.7 17.2 1.2 1 0 0 1 1 1 0 Atrophin-1 family GREB1 PF15782.5 KXS22095.1 - 2.5 5.1 9.4 2.6 5.0 9.4 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SR-25 PF10500.9 KXS22095.1 - 2.5 7.7 27.8 3.6 7.1 27.8 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RNA_pol_Rbc25 PF08292.12 KXS22095.1 - 2.5 8.3 6.6 3.6 7.8 6.6 1.3 1 0 0 1 1 1 0 RNA polymerase III subunit Rpc25 TRAP_alpha PF03896.16 KXS22095.1 - 3.7 6.7 9.4 4.7 6.3 9.4 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Zip PF02535.22 KXS22095.1 - 4 6.6 8.3 4.7 6.3 8.3 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter TERB2 PF15101.6 KXS22095.1 - 4.8 7.2 12.6 6.6 6.7 12.6 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Hid1 PF12722.7 KXS22095.1 - 5.4 5.0 10.2 5.7 4.9 10.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RR_TM4-6 PF06459.12 KXS22095.1 - 7.2 6.3 18.2 9.8 5.9 18.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Vfa1 PF08432.10 KXS22095.1 - 8.3 6.7 25.1 11 6.3 25.1 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 SH3_9 PF14604.6 KXS22096.1 - 1.6e-05 24.6 0.0 3e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Beta-APP PF03494.13 KXS22096.1 - 1 9.3 7.0 2 8.3 7.0 1.4 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) AAA PF00004.29 KXS22098.1 - 2.3e-39 134.8 0.0 1.3e-38 132.4 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KXS22098.1 - 3.7e-09 36.2 0.0 1.1e-08 34.8 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 KXS22098.1 - 5.4e-07 29.7 0.1 3.5e-05 23.8 0.1 2.9 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KXS22098.1 - 1.2e-06 28.9 0.2 0.0023 18.2 0.1 3.1 2 1 0 3 3 3 1 AAA domain RuvB_N PF05496.12 KXS22098.1 - 1.6e-06 27.9 0.0 5.6e-06 26.2 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 KXS22098.1 - 4.7e-06 26.5 0.0 9e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_16 PF13191.6 KXS22098.1 - 1.9e-05 25.1 0.4 0.00075 19.9 0.4 3.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 KXS22098.1 - 0.0005 19.6 0.0 0.0014 18.1 0.0 1.8 2 0 0 2 2 2 1 P-loop containing dynein motor region Mg_chelatase PF01078.21 KXS22098.1 - 0.0012 18.2 0.0 0.0025 17.2 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 KXS22098.1 - 0.0013 19.3 0.0 0.0032 18.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 KXS22098.1 - 0.0018 18.4 0.0 0.006 16.7 0.0 1.9 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 KXS22098.1 - 0.0022 17.2 0.0 0.0039 16.5 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 KXS22098.1 - 0.0033 17.6 0.0 0.0074 16.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KXS22098.1 - 0.0042 17.1 0.0 0.014 15.5 0.0 1.8 2 0 0 2 2 1 1 AAA domain Hydin_ADK PF17213.3 KXS22098.1 - 0.0094 16.3 0.1 4.2 7.6 0.0 2.4 2 0 0 2 2 2 1 Hydin Adenylate kinase-like domain AAA_24 PF13479.6 KXS22098.1 - 0.0097 15.7 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.11 KXS22098.1 - 0.012 15.5 0.0 0.03 14.2 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 KXS22098.1 - 0.012 15.0 0.0 2.9 7.3 0.0 2.7 1 1 1 2 2 2 0 Bacterial TniB protein AAA_8 PF12780.7 KXS22098.1 - 0.018 14.4 0.1 0.37 10.1 0.0 2.8 2 1 1 3 3 3 0 P-loop containing dynein motor region D4 RNA_helicase PF00910.22 KXS22098.1 - 0.019 15.3 0.0 0.036 14.4 0.0 1.6 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.12 KXS22098.1 - 0.024 14.5 0.0 0.063 13.2 0.0 1.8 1 0 0 1 1 1 0 NACHT domain AAA_25 PF13481.6 KXS22098.1 - 0.033 13.8 1.7 0.1 12.2 0.2 2.3 2 1 0 2 2 2 0 AAA domain PhoH PF02562.16 KXS22098.1 - 0.038 13.5 0.1 0.082 12.4 0.1 1.5 1 0 0 1 1 1 0 PhoH-like protein DUF815 PF05673.13 KXS22098.1 - 0.045 12.9 0.0 0.075 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) TsaE PF02367.17 KXS22098.1 - 0.047 13.7 0.1 0.092 12.7 0.1 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 KXS22098.1 - 0.05 13.8 0.0 0.13 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 KXS22098.1 - 0.08 12.7 0.0 0.25 11.0 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 KXS22098.1 - 0.087 12.9 0.0 0.23 11.6 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain ABC_tran PF00005.27 KXS22098.1 - 0.13 12.8 0.3 0.89 10.1 0.1 2.5 2 1 0 2 2 2 0 ABC transporter ATPase PF06745.13 KXS22098.1 - 0.15 11.3 0.4 0.69 9.2 0.2 1.9 1 1 1 2 2 2 0 KaiC AAA_19 PF13245.6 KXS22098.1 - 0.79 10.0 2.4 1.8 8.9 1.1 2.5 2 1 0 2 2 1 0 AAA domain CM_2 PF01817.21 KXS22100.1 - 0.00044 20.5 0.3 0.18 12.2 0.0 2.7 2 1 0 2 2 2 2 Chorismate mutase type II FCD PF07729.12 KXS22100.1 - 0.087 13.2 0.1 0.18 12.2 0.1 1.5 1 0 0 1 1 1 0 FCD domain HEAT_EZ PF13513.6 KXS22101.1 - 2.3e-36 123.8 19.2 1.4e-12 47.8 0.1 11.1 8 3 3 11 11 10 7 HEAT-like repeat HEAT PF02985.22 KXS22101.1 - 3.9e-23 79.5 18.7 0.00088 19.3 0.0 11.1 14 0 0 14 14 9 6 HEAT repeat HEAT_2 PF13646.6 KXS22101.1 - 1.2e-16 60.8 2.3 0.0027 18.1 0.0 8.0 4 3 4 9 9 9 4 HEAT repeats IBN_N PF03810.19 KXS22101.1 - 9.6e-13 47.9 0.7 2.3e-11 43.4 0.1 3.5 3 0 0 3 3 3 1 Importin-beta N-terminal domain Cnd1 PF12717.7 KXS22101.1 - 3.3e-12 46.7 0.0 0.0075 16.3 0.0 5.5 5 0 0 5 5 5 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 KXS22101.1 - 4.2e-10 40.1 0.0 0.31 11.7 0.1 6.3 4 2 3 7 7 6 3 Vacuolar 14 Fab1-binding region Arm PF00514.23 KXS22101.1 - 8.6e-09 35.1 7.2 0.084 13.0 0.0 6.8 7 0 0 7 7 7 2 Armadillo/beta-catenin-like repeat CLASP_N PF12348.8 KXS22101.1 - 8e-07 28.8 0.2 0.0078 15.8 0.0 5.5 5 4 2 8 8 8 1 CLASP N terminal Adaptin_N PF01602.20 KXS22101.1 - 1.5e-06 27.1 0.0 0.008 14.8 0.1 3.7 2 2 0 3 3 3 2 Adaptin N terminal region DUF3437 PF11919.8 KXS22101.1 - 5.6e-05 23.0 0.2 6.8 6.7 0.0 5.4 5 1 1 6 6 6 1 Domain of unknown function (DUF3437) Dopey_N PF04118.14 KXS22101.1 - 0.0038 16.4 0.0 0.012 14.7 0.0 1.9 2 0 0 2 2 2 1 Dopey, N-terminal UME PF08064.13 KXS22101.1 - 0.0084 16.0 0.3 0.85 9.6 0.0 3.9 6 0 0 6 6 4 1 UME (NUC010) domain TIP120 PF08623.10 KXS22101.1 - 0.0084 15.9 0.0 9.5 6.0 0.0 4.8 6 0 0 6 6 6 0 TATA-binding protein interacting (TIP20) Tti2 PF10521.9 KXS22101.1 - 0.011 15.3 0.4 9.3 5.7 0.0 4.3 6 0 0 6 6 6 0 Tti2 family ParcG PF10274.9 KXS22101.1 - 0.024 14.8 0.8 0.96 9.5 0.1 3.6 2 1 1 3 3 3 0 Parkin co-regulated protein Cnd3 PF12719.7 KXS22101.1 - 0.046 12.9 0.2 0.22 10.7 0.1 2.3 2 0 0 2 2 2 0 Nuclear condensing complex subunits, C-term domain RTP1_C1 PF10363.9 KXS22101.1 - 0.086 13.0 0.1 29 4.9 0.0 4.3 5 0 0 5 5 5 0 Required for nuclear transport of RNA pol II C-terminus 1 DUF1981 PF09324.10 KXS22101.1 - 0.093 12.6 0.1 3.1 7.7 0.0 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF1981) V-ATPase_H_C PF11698.8 KXS22101.1 - 0.14 12.2 0.0 28 4.9 0.0 3.6 4 1 0 5 5 5 0 V-ATPase subunit H Xpo1 PF08389.12 KXS22101.1 - 0.15 12.2 0.6 30 4.6 0.0 3.9 4 0 0 4 4 4 0 Exportin 1-like protein NUC130_3NT PF08158.12 KXS22101.1 - 0.23 11.8 2.1 0.99 9.8 0.0 3.0 3 0 0 3 3 3 0 NUC130/3NT domain Ric8 PF10165.9 KXS22102.1 - 2e-68 231.6 0.0 1.7e-57 195.5 0.0 2.0 1 1 1 2 2 2 2 Guanine nucleotide exchange factor synembryn PhoLip_ATPase_C PF16212.5 KXS22103.1 - 2.3e-77 260.1 18.0 2.3e-77 260.1 18.0 1.8 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KXS22103.1 - 3.5e-25 87.5 5.4 1e-24 86.0 5.4 1.9 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 KXS22103.1 - 4.9e-12 45.8 0.0 2.4e-11 43.6 0.0 2.1 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KXS22103.1 - 4.3e-11 43.5 1.9 1.3e-06 28.8 0.7 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KXS22103.1 - 7.4e-09 35.4 0.0 2.1e-08 33.9 0.0 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KXS22103.1 - 0.00074 19.3 0.1 0.016 14.9 0.0 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase CBFD_NFYB_HMF PF00808.23 KXS22104.1 - 9e-15 54.7 1.2 1.3e-14 54.2 1.2 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KXS22104.1 - 7.6e-06 26.3 0.2 1.2e-05 25.7 0.2 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 tRNA-synt_His PF13393.6 KXS22105.1 - 1.8e-44 152.3 0.0 2.2e-44 152.0 0.0 1.1 1 0 0 1 1 1 1 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 KXS22105.1 - 2.7e-13 49.9 0.1 6.1e-13 48.7 0.1 1.6 1 0 0 1 1 1 1 Anticodon binding domain HGTP_anticodon2 PF12745.7 KXS22105.1 - 0.00015 21.4 0.0 0.00022 20.8 0.0 1.1 1 0 0 1 1 1 1 Anticodon binding domain of tRNAs tRNA-synt_2 PF00152.20 KXS22105.1 - 0.0031 16.7 1.9 0.082 12.0 0.5 2.7 2 1 0 2 2 2 1 tRNA synthetases class II (D, K and N) AsmA_2 PF13502.6 KXS22105.1 - 0.21 11.1 0.0 0.35 10.3 0.0 1.4 1 0 0 1 1 1 0 AsmA-like C-terminal region YTH PF04146.15 KXS22107.1 - 7.9e-37 126.8 0.7 2.9e-35 121.6 0.7 2.2 1 1 0 1 1 1 1 YT521-B-like domain HMG-CoA_red PF00368.18 KXS22108.1 - 2.3e-90 303.3 0.0 3.1e-90 302.8 0.0 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase Pkinase PF00069.25 KXS22109.1 - 8.2e-77 258.1 0.0 9.3e-77 257.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS22109.1 - 1e-33 116.7 0.0 1.2e-33 116.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KXS22109.1 - 0.00031 19.8 0.0 0.0059 15.6 0.0 2.1 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KXS22109.1 - 0.0011 18.4 0.0 0.012 15.0 0.0 2.1 1 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 KXS22109.1 - 0.015 14.6 0.0 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXS22109.1 - 0.052 13.5 0.1 0.13 12.1 0.1 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KXS22109.1 - 0.14 11.2 0.1 0.23 10.5 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 UBN_AB PF14075.6 KXS22110.1 - 6e-14 52.3 0.2 6e-14 52.3 0.2 2.4 2 1 0 2 2 2 1 Ubinuclein conserved middle domain HUN PF08729.10 KXS22110.1 - 3e-07 30.3 0.7 3e-07 30.3 0.7 2.4 2 0 0 2 2 2 1 HPC2 and ubinuclein domain RICTOR_N PF14664.6 KXS22111.1 - 9.8e-82 274.9 8.8 8.5e-81 271.8 5.9 3.0 2 1 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, N-term RasGEF_N_2 PF14663.6 KXS22111.1 - 7.4e-36 122.8 1.0 4.7e-34 117.0 0.1 3.6 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_M PF14666.6 KXS22111.1 - 2.7e-35 120.3 0.0 9e-33 112.2 0.0 4.0 4 1 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, middle domain RICTOR_V PF14668.6 KXS22111.1 - 7.4e-16 58.2 0.1 1.2e-13 51.1 0.0 3.7 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, domain 5 HEAT PF02985.22 KXS22111.1 - 8.7e-06 25.6 6.4 0.27 11.6 0.0 6.2 6 0 0 6 6 6 2 HEAT repeat Pterin_bind PF00809.22 KXS22112.1 - 1.3e-84 283.7 0.3 2e-84 283.1 0.3 1.3 1 0 0 1 1 1 1 Pterin binding enzyme FolB PF02152.18 KXS22112.1 - 1.8e-52 176.5 2.5 1.1e-26 93.5 0.3 2.5 2 0 0 2 2 2 2 Dihydroneopterin aldolase HPPK PF01288.20 KXS22112.1 - 7.2e-36 123.1 0.0 2.4e-35 121.4 0.0 2.0 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) BTB_3 PF16017.5 KXS22113.1 - 0.06 13.5 0.0 7.1 6.8 0.0 2.4 2 0 0 2 2 2 0 BTB/POZ domain JmjC PF02373.22 KXS22114.1 - 1e-05 26.0 0.0 2e-05 25.0 0.0 1.6 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 KXS22114.1 - 0.0012 18.6 0.0 0.0022 17.7 0.0 1.3 1 0 0 1 1 1 1 Cupin-like domain Cupin_2 PF07883.11 KXS22114.1 - 0.0024 17.6 0.2 0.015 15.0 0.0 2.5 2 1 0 2 2 2 1 Cupin domain Cupin_4 PF08007.12 KXS22114.1 - 0.0033 17.0 0.0 0.0047 16.4 0.0 1.2 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_6 PF12852.7 KXS22114.1 - 0.0042 16.8 0.1 0.0076 16.0 0.1 1.3 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.19 KXS22114.1 - 0.0094 15.9 0.0 0.02 14.8 0.0 1.5 1 0 0 1 1 1 1 AraC-like ligand binding domain Pkinase PF00069.25 KXS22115.1 - 1.7e-54 184.9 0.0 3.1e-38 131.7 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 KXS22115.1 - 1.5e-35 122.8 0.0 6.5e-33 114.1 0.0 3.4 4 0 0 4 4 4 1 Protein tyrosine kinase DUF3543 PF12063.8 KXS22115.1 - 1.4e-23 83.5 0.0 2.2e-23 82.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Kinase-like PF14531.6 KXS22115.1 - 0.032 13.6 0.0 0.18 11.1 0.0 2.1 1 1 0 1 1 1 0 Kinase-like APH PF01636.23 KXS22115.1 - 3.4 7.5 5.7 4.6 7.1 0.7 2.7 2 1 0 2 2 2 0 Phosphotransferase enzyme family WD40 PF00400.32 KXS22116.1 - 2.8e-32 110.2 18.1 1e-10 42.0 0.4 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXS22116.1 - 1.1e-07 32.0 0.0 0.016 15.5 0.0 3.8 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KXS22116.1 - 1e-05 25.5 0.3 0.099 12.5 0.1 3.2 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KXS22116.1 - 4.2e-05 22.4 4.4 0.67 8.5 0.4 3.2 1 1 1 3 3 3 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KXS22116.1 - 9.4e-05 21.5 1.6 0.72 8.7 0.2 3.6 2 1 3 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 KXS22116.1 - 0.0029 16.2 0.1 0.015 13.8 0.0 2.2 1 1 1 2 2 2 2 Cytochrome D1 heme domain WD40_like PF17005.5 KXS22116.1 - 0.0041 16.5 0.0 0.96 8.7 0.0 2.7 3 0 0 3 3 3 2 WD40-like domain Npa1 PF11707.8 KXS22117.1 - 1.7e-21 77.0 0.0 4e-21 75.8 0.0 1.7 1 0 0 1 1 1 1 Ribosome 60S biogenesis N-terminal Peptidase_S10 PF00450.22 KXS22118.1 - 5.1e-79 266.6 0.0 6.4e-79 266.3 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase LRR_4 PF12799.7 KXS22120.1 - 3.9e-11 43.0 2.6 0.0084 16.5 0.0 3.8 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXS22120.1 - 1.1e-06 28.3 4.6 0.026 14.3 0.1 3.5 1 1 2 3 3 3 3 Leucine rich repeat LRR_9 PF14580.6 KXS22120.1 - 0.11 12.0 0.6 0.24 10.9 0.6 1.6 1 0 0 1 1 1 0 Leucine-rich repeat LRR_6 PF13516.6 KXS22120.1 - 0.18 12.0 0.5 16 5.9 0.1 3.5 4 0 0 4 4 4 0 Leucine Rich repeat Oxidored_q6 PF01058.22 KXS22121.1 - 5.9e-22 77.9 0.1 8e-22 77.5 0.1 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit CorA PF01544.18 KXS22122.1 - 1.9e-44 152.1 0.3 2.4e-44 151.8 0.3 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Cupin_2 PF07883.11 KXS22127.1 - 0.12 12.1 1.3 0.36 10.6 1.3 1.8 1 0 0 1 1 1 0 Cupin domain Na_H_Exchanger PF00999.21 KXS22128.1 - 9.3e-58 195.8 41.4 1.7e-57 195.0 41.4 1.3 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DcpS_C PF11969.8 KXS22129.1 - 0.034 14.6 3.4 4.2 7.9 0.1 2.7 2 0 0 2 2 2 0 Scavenger mRNA decapping enzyme C-term binding DEAD PF00270.29 KXS22130.1 - 3.4e-18 66.0 0.0 4.7e-18 65.6 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KXS22130.1 - 7e-12 45.7 0.0 9.7e-12 45.2 0.0 1.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KXS22130.1 - 0.0014 18.9 0.0 0.0025 18.1 0.0 1.4 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 KXS22130.1 - 0.025 14.0 0.0 0.04 13.4 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein T2SSE PF00437.20 KXS22130.1 - 0.041 12.9 0.0 0.056 12.5 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein IstB_IS21 PF01695.17 KXS22130.1 - 0.12 12.1 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Helicase_C PF00271.31 KXS22131.1 - 4.7e-05 23.7 0.0 0.00018 21.8 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RNase_P_p30 PF01876.16 KXS22132.1 - 6.4e-54 182.7 0.0 1.4e-50 171.8 0.0 2.1 2 0 0 2 2 2 2 RNase P subunit p30 SnoaL_2 PF12680.7 KXS22133.1 - 0.0035 18.0 0.4 0.011 16.3 0.1 2.1 1 1 1 2 2 2 1 SnoaL-like domain WD40 PF00400.32 KXS22135.1 - 1.6e-13 50.9 3.0 0.0023 18.7 0.2 6.3 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXS22135.1 - 1.5e-05 25.2 0.0 1 9.7 0.0 4.6 2 1 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KXS22135.1 - 0.074 12.0 0.0 0.15 11.0 0.0 1.4 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Aldedh PF00171.22 KXS22136.1 - 6.5e-87 292.0 0.0 8e-87 291.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Ank_2 PF12796.7 KXS22137.1 - 3.6e-15 56.3 0.0 6.6e-07 29.8 0.0 3.9 2 1 1 4 4 4 2 Ankyrin repeats (3 copies) Ank PF00023.30 KXS22137.1 - 8.8e-12 44.9 1.2 0.0043 17.4 0.0 5.1 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.6 KXS22137.1 - 2.1e-11 43.0 0.6 0.077 13.6 0.0 5.4 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 KXS22137.1 - 1.1e-07 32.0 1.6 0.0069 16.7 0.0 5.0 2 2 3 5 5 5 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXS22137.1 - 4.1e-07 30.4 0.3 7.4e-05 23.2 0.0 3.9 4 1 1 5 5 5 1 Ankyrin repeats (many copies) MCM PF00493.23 KXS22138.1 - 1.2e-101 338.6 0.0 1.8e-101 337.9 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KXS22138.1 - 2.7e-35 120.9 0.1 4.8e-35 120.2 0.1 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KXS22138.1 - 4e-28 97.7 0.7 1.3e-27 96.0 0.7 2.0 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KXS22138.1 - 9.2e-16 58.3 0.5 2e-15 57.2 0.5 1.6 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KXS22138.1 - 6.8e-07 28.9 0.0 0.00031 20.2 0.0 2.3 1 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KXS22138.1 - 3.1e-05 24.0 0.0 7.6e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KXS22138.1 - 6.4e-05 22.8 0.0 0.001 18.9 0.0 2.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF134 PF02001.16 KXS22138.1 - 0.014 15.9 1.0 0.61 10.7 0.3 3.1 2 1 1 3 3 3 0 Protein of unknown function DUF134 Sigma54_activat PF00158.26 KXS22138.1 - 0.053 13.2 0.0 1.1 8.9 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain Laminin_II PF06009.12 KXS22139.1 - 0.02 14.9 1.1 0.049 13.6 1.3 1.5 1 1 1 2 2 2 0 Laminin Domain II Prefoldin_2 PF01920.20 KXS22139.1 - 0.027 14.4 1.1 0.04 13.9 1.1 1.3 1 1 0 1 1 1 0 Prefoldin subunit Seryl_tRNA_N PF02403.22 KXS22139.1 - 0.064 13.5 0.9 0.31 11.3 1.0 1.8 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain BRE1 PF08647.11 KXS22139.1 - 0.073 13.2 0.7 0.18 11.9 0.7 1.7 1 1 0 1 1 1 0 BRE1 E3 ubiquitin ligase DUF1664 PF07889.12 KXS22139.1 - 0.081 13.0 0.5 11 6.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) bZIP_1 PF00170.21 KXS22139.1 - 0.38 10.9 1.7 1.5 9.0 1.0 2.1 2 1 1 3 3 3 0 bZIP transcription factor LMBR1 PF04791.16 KXS22140.1 - 2.2e-40 139.1 7.4 3.6e-28 98.8 0.0 2.1 1 1 1 2 2 2 2 LMBR1-like membrane protein RRF PF01765.19 KXS22141.1 - 1.1e-44 152.2 2.9 1.6e-44 151.7 2.9 1.2 1 0 0 1 1 1 1 Ribosome recycling factor YtxH PF12732.7 KXS22141.1 - 0.025 15.1 2.7 0.025 15.1 2.7 1.7 2 0 0 2 2 2 0 YtxH-like protein CSN5_C PF18323.1 KXS22141.1 - 0.88 10.5 9.0 0.2 12.6 2.9 2.4 3 0 0 3 3 3 0 Cop9 signalosome subunit 5 C-terminal domain DUF3767 PF12597.8 KXS22142.1 - 3.9e-18 65.1 0.0 4.8e-18 64.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) NADH_dh_m_C1 PF15088.6 KXS22142.1 - 0.11 12.2 0.2 0.2 11.3 0.2 1.4 1 0 0 1 1 1 0 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial WD40 PF00400.32 KXS22143.1 - 1.3e-37 127.1 18.5 3e-06 27.8 0.1 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXS22143.1 - 5.5e-14 52.2 2.7 0.0092 16.3 0.0 6.3 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KXS22143.1 - 1.3e-08 34.6 0.0 3.1e-08 33.3 0.0 1.7 1 1 1 2 2 2 1 WD40-like domain CLTH PF10607.9 KXS22143.1 - 0.00035 20.5 0.1 0.00061 19.7 0.1 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain eIF2A PF08662.11 KXS22143.1 - 0.0015 18.5 0.1 0.032 14.1 0.0 2.8 2 1 2 4 4 4 1 Eukaryotic translation initiation factor eIF2A DUF4221 PF13970.6 KXS22143.1 - 0.013 15.0 0.0 0.026 14.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4221) Nucleoporin_N PF08801.11 KXS22143.1 - 0.094 11.4 0.1 1.5 7.5 0.0 2.7 2 2 1 3 3 3 0 Nup133 N terminal like DEAD PF00270.29 KXS22144.1 - 1e-45 155.7 1.0 2.1e-45 154.7 1.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXS22144.1 - 4.5e-32 110.7 0.5 2.4e-31 108.3 0.1 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain AAA_19 PF13245.6 KXS22144.1 - 2e-05 25.0 0.6 0.00034 21.0 0.1 2.2 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 KXS22144.1 - 2.4e-05 24.4 0.0 4.4e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 KXS22144.1 - 0.0021 17.8 0.7 0.0043 16.8 0.7 1.5 1 1 0 1 1 1 1 AAA domain UTP25 PF06862.12 KXS22144.1 - 0.0058 15.5 0.2 1.4 7.6 0.0 2.2 2 0 0 2 2 2 2 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 CMS1 PF14617.6 KXS22144.1 - 0.021 14.2 0.0 0.048 13.0 0.0 1.6 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit UvrD-helicase PF00580.21 KXS22144.1 - 0.021 14.4 0.3 0.042 13.4 0.2 1.3 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain tRNA-synt_1b PF00579.25 KXS22144.1 - 0.05 12.9 0.0 0.13 11.6 0.0 1.7 1 0 0 1 1 1 0 tRNA synthetases class I (W and Y) Flavi_DEAD PF07652.14 KXS22144.1 - 0.057 13.4 0.1 0.29 11.1 0.1 2.3 1 1 0 1 1 1 0 Flavivirus DEAD domain Helicase_RecD PF05127.14 KXS22144.1 - 0.077 12.9 0.1 0.15 11.9 0.1 1.5 1 0 0 1 1 1 0 Helicase DDE_Tnp_4 PF13359.6 KXS22147.1 - 5e-08 32.8 0.0 7.2e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease FAD_binding_3 PF01494.19 KXS22148.1 - 0.0086 15.4 0.0 0.0089 15.3 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Shikimate_DH PF01488.20 KXS22148.1 - 0.075 13.1 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF364 PF04016.12 KXS22149.1 - 0.002 17.8 0.0 0.014 14.9 0.0 2.3 2 1 0 2 2 2 1 Putative heavy-metal chelation Methyltransf_23 PF13489.6 KXS22149.1 - 0.12 12.2 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Rrp15p PF07890.12 KXS22151.1 - 1.1e-24 87.3 5.3 1.1e-24 87.3 5.3 2.0 3 0 0 3 3 3 1 Rrp15p DUF2564 PF10819.8 KXS22151.1 - 0.39 11.1 3.7 0.84 10.1 0.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2564) WD40 PF00400.32 KXS22152.1 - 0.0067 17.2 0.1 0.063 14.2 0.1 2.5 2 1 0 2 2 2 1 WD domain, G-beta repeat PLDc_2 PF13091.6 KXS22154.1 - 2.6e-19 69.4 0.0 1e-10 41.6 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 KXS22154.1 - 0.00058 19.9 3.6 0.22 11.8 0.0 2.8 2 1 0 2 2 2 2 Phospholipase D Active site motif RE_NgoFVII PF09565.10 KXS22154.1 - 0.19 11.0 0.0 7 5.9 0.0 2.2 2 0 0 2 2 2 0 NgoFVII restriction endonuclease HOOK PF05622.12 KXS22155.1 - 1.3e-50 172.3 54.8 6.8e-44 150.1 24.8 2.9 1 1 2 3 3 3 2 HOOK protein MAD PF05557.13 KXS22155.1 - 0.0019 16.6 9.6 0.0019 16.6 9.6 3.2 1 1 2 3 3 3 3 Mitotic checkpoint protein Bacillus_HBL PF05791.11 KXS22155.1 - 0.11 12.3 0.2 0.11 12.3 0.2 5.0 5 2 1 6 6 6 0 Bacillus haemolytic enterotoxin (HBL) NdhM PF10664.9 KXS22155.1 - 0.14 12.5 0.6 13 6.1 0.1 2.8 2 0 0 2 2 2 0 Cyanobacterial and plastid NDH-1 subunit M 3HCDH_RFF PF18321.1 KXS22155.1 - 0.2 12.1 2.3 2 9.0 0.3 2.8 2 0 0 2 2 2 0 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain Tup_N PF08581.10 KXS22155.1 - 0.83 10.0 20.4 3.3 8.1 2.0 5.1 4 1 0 4 4 4 0 Tup N-terminal XLF PF09302.11 KXS22155.1 - 4.2 7.5 19.7 8.5 6.5 10.8 4.7 2 2 1 3 3 3 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component CENP-F_leu_zip PF10473.9 KXS22155.1 - 6.3 6.8 65.7 0.17 11.9 12.8 5.6 2 2 4 6 6 6 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 WD40_alt PF14077.6 KXS22155.1 - 9.7 6.2 7.9 6.6 6.7 0.0 4.0 4 0 0 4 4 4 0 Alternative WD40 repeat motif Bromodomain PF00439.25 KXS22156.1 - 8.9e-08 32.1 0.0 5.4e-07 29.6 0.0 2.0 1 1 1 2 2 2 2 Bromodomain NuA4 PF09340.10 KXS22157.1 - 2.4e-27 94.6 1.4 5.5e-27 93.5 1.4 1.6 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 Enkurin PF13864.6 KXS22157.1 - 0.11 13.0 0.4 0.11 13.0 0.4 2.5 2 0 0 2 2 2 0 Calmodulin-binding LMBR1 PF04791.16 KXS22157.1 - 0.37 9.7 1.9 0.42 9.5 1.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Sec8_exocyst PF04048.14 KXS22157.1 - 3.1 7.7 8.9 1.2 9.1 2.8 2.1 1 1 0 2 2 2 0 Sec8 exocyst complex component specific domain DHR10 PF18595.1 KXS22157.1 - 6.5 6.8 15.8 7.9 6.6 3.6 2.5 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain Pkinase PF00069.25 KXS22158.1 - 1.1e-49 169.2 0.0 1.5e-49 168.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS22158.1 - 7.5e-35 120.5 0.0 1.4e-34 119.6 0.0 1.4 1 1 1 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KXS22158.1 - 0.00019 21.5 0.0 0.00039 20.4 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KXS22158.1 - 0.0012 18.3 0.0 0.0022 17.4 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 KXS22158.1 - 0.015 14.6 0.0 0.024 14.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KXS22158.1 - 0.12 11.1 0.0 0.2 10.4 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Dpy-30 PF05186.13 KXS22159.1 - 2.4e-17 62.3 0.1 5.6e-17 61.1 0.1 1.7 1 0 0 1 1 1 1 Dpy-30 motif ADK PF00406.22 KXS22159.1 - 2.7e-11 43.8 0.2 3.9e-05 23.8 0.3 2.8 2 1 0 2 2 2 2 Adenylate kinase AAA_17 PF13207.6 KXS22159.1 - 3.8e-10 40.3 4.9 6.6e-09 36.3 0.2 3.4 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KXS22159.1 - 1.5e-09 38.4 1.3 5.2e-09 36.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain Hydin_ADK PF17213.3 KXS22159.1 - 1.5e-07 32.0 2.4 2.3e-06 28.1 0.1 3.1 3 0 0 3 3 3 1 Hydin Adenylate kinase-like domain AAA_33 PF13671.6 KXS22159.1 - 1.1e-06 28.8 3.0 2.8e-06 27.5 0.0 2.8 2 1 0 2 2 1 1 AAA domain AAA_28 PF13521.6 KXS22159.1 - 3.3e-05 24.2 7.2 4.6e-05 23.7 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA PF00004.29 KXS22159.1 - 5.2e-05 23.7 0.1 0.00018 22.0 0.0 2.0 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KXS22159.1 - 0.00029 21.3 0.0 0.0016 18.9 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KXS22159.1 - 0.0011 19.3 0.1 0.012 15.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 KXS22159.1 - 0.002 18.1 0.0 0.011 15.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain KTI12 PF08433.10 KXS22159.1 - 0.0029 17.1 0.2 0.032 13.7 0.0 2.5 2 0 0 2 2 2 1 Chromatin associated protein KTI12 Cytidylate_kin2 PF13189.6 KXS22159.1 - 0.0034 17.6 0.6 0.0097 16.1 0.0 2.1 2 0 0 2 2 1 1 Cytidylate kinase-like family Cytidylate_kin PF02224.18 KXS22159.1 - 0.004 16.9 0.0 0.0092 15.7 0.0 1.6 1 0 0 1 1 1 1 Cytidylate kinase SKI PF01202.22 KXS22159.1 - 0.0057 16.8 0.2 0.044 13.9 0.0 2.6 3 0 0 3 3 3 1 Shikimate kinase AAA_24 PF13479.6 KXS22159.1 - 0.019 14.7 0.0 0.044 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain dNK PF01712.19 KXS22159.1 - 0.051 13.4 0.2 0.26 11.1 0.0 2.1 2 0 0 2 2 2 0 Deoxynucleoside kinase Epimerase PF01370.21 KXS22159.1 - 0.069 12.6 0.0 0.16 11.4 0.0 1.6 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Herpes_US12 PF05363.12 KXS22159.1 - 0.14 12.9 3.4 0.089 13.5 0.8 1.9 2 0 0 2 2 1 0 Herpesvirus US12 family RuvB_N PF05496.12 KXS22159.1 - 0.15 11.8 0.0 0.32 10.7 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_11 PF13086.6 KXS22159.1 - 0.3 10.8 2.9 12 5.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 KXS22159.1 - 7.3 7.0 7.0 1.1e+02 3.2 0.0 2.7 3 0 0 3 3 3 0 AAA domain SAS-6_N PF16531.5 KXS22160.1 - 9.9e-12 45.3 0.0 2e-11 44.3 0.0 1.6 1 0 0 1 1 1 1 Centriolar protein SAS N-terminal AAA_13 PF13166.6 KXS22160.1 - 1.5e-05 23.9 11.4 1.5e-05 23.9 11.4 2.1 1 1 1 2 2 2 1 AAA domain DUF4200 PF13863.6 KXS22160.1 - 0.0055 17.1 11.6 0.0055 17.1 11.6 3.9 1 1 3 4 4 4 1 Domain of unknown function (DUF4200) Exonuc_VII_S PF02609.16 KXS22160.1 - 0.0083 16.2 9.7 0.13 12.4 0.2 3.8 3 0 0 3 3 3 2 Exonuclease VII small subunit DUF1664 PF07889.12 KXS22160.1 - 0.27 11.3 23.5 3.1 7.9 0.7 4.5 2 1 3 5 5 5 0 Protein of unknown function (DUF1664) DUF812 PF05667.11 KXS22160.1 - 3.4 6.5 52.5 0.84 8.4 11.1 2.9 1 1 0 2 2 2 0 Protein of unknown function (DUF812) Spc7 PF08317.11 KXS22160.1 - 4.7 6.0 56.9 0.092 11.6 16.5 3.1 1 1 3 4 4 4 0 Spc7 kinetochore protein BLOC1_2 PF10046.9 KXS22160.1 - 4.9 7.5 21.4 8.2 6.8 4.7 3.7 1 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Glyco_hydro_2_C PF02836.17 KXS22161.1 - 1e-65 221.9 0.0 3.2e-64 216.9 0.0 2.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.17 KXS22161.1 - 2.8e-59 200.7 0.0 4.4e-59 200.0 0.0 1.3 1 0 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.18 KXS22161.1 - 2.2e-28 99.3 0.0 4.9e-28 98.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain DUF4981 PF16353.5 KXS22161.1 - 6.5e-18 65.0 0.0 2.3e-17 63.3 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function(DUF4981) Glyco_hydro_2 PF00703.21 KXS22161.1 - 1.1e-09 39.0 0.0 2.1e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 DUF2012 PF09430.10 KXS22161.1 - 0.18 11.9 0.0 0.46 10.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2012) Caleosin PF05042.13 KXS22162.1 - 5.2e-77 257.5 0.2 6.5e-77 257.3 0.2 1.1 1 0 0 1 1 1 1 Caleosin related protein EF-hand_1 PF00036.32 KXS22162.1 - 1.2e-06 27.6 1.0 0.00017 20.9 0.1 2.4 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 KXS22162.1 - 2.1e-06 27.2 0.2 0.00056 19.6 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 KXS22162.1 - 9.6e-05 22.8 0.1 0.06 13.8 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 KXS22162.1 - 0.00022 21.0 0.4 0.055 13.3 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KXS22162.1 - 0.0083 15.6 1.1 1.9 8.1 0.2 2.5 2 0 0 2 2 2 2 EF hand Pro_CA PF00484.19 KXS22163.1 - 1.6e-12 48.0 0.0 3.6e-12 46.9 0.0 1.5 1 1 0 1 1 1 1 Carbonic anhydrase Malic_M PF03949.15 KXS22164.1 - 1.2e-84 283.6 0.0 1.6e-84 283.2 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 KXS22164.1 - 2.1e-58 197.1 0.0 3.3e-58 196.5 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain dsrm PF00035.26 KXS22165.1 - 0.0066 17.1 0.0 0.028 15.1 0.0 2.0 2 0 0 2 2 2 1 Double-stranded RNA binding motif ubiquitin PF00240.23 KXS22166.1 - 4.4e-13 48.8 0.0 7e-13 48.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family zf-AN1 PF01428.16 KXS22166.1 - 6.3e-05 23.1 5.5 0.00013 22.1 5.5 1.5 1 0 0 1 1 1 1 AN1-like Zinc finger Rad60-SLD PF11976.8 KXS22166.1 - 0.00094 19.0 0.0 0.0015 18.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KXS22166.1 - 0.0032 17.9 0.0 0.0057 17.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain OrfB_Zn_ribbon PF07282.11 KXS22167.1 - 2e-05 24.4 0.3 2e-05 24.4 0.3 2.2 2 1 0 2 2 2 1 Putative transposase DNA-binding domain NmrA PF05368.13 KXS22168.1 - 3.5e-28 98.8 0.0 4.3e-28 98.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXS22168.1 - 1.9e-15 57.2 0.1 3.3e-14 53.2 0.0 2.1 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 KXS22168.1 - 1.1e-05 25.0 0.0 0.00012 21.6 0.0 2.3 1 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXS22168.1 - 0.00011 21.3 0.0 0.00026 20.1 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.20 KXS22168.1 - 0.0081 16.3 0.1 0.018 15.1 0.1 1.8 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus YcaO PF02624.16 KXS22168.1 - 0.034 13.4 0.0 0.052 12.8 0.0 1.2 1 0 0 1 1 1 0 YcaO cyclodehydratase, ATP-ad Mg2+-binding Polysacc_synt_2 PF02719.15 KXS22168.1 - 0.14 11.2 0.5 7.6 5.6 0.0 2.5 3 0 0 3 3 3 0 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KXS22168.1 - 0.23 10.8 0.0 0.63 9.4 0.0 1.6 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Zn_ribbon_17 PF17120.5 KXS22169.1 - 6.7e-15 54.4 12.6 6.7e-15 54.4 12.6 2.1 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type WD40 PF00400.32 KXS22169.1 - 2.2e-08 34.6 17.3 0.27 12.2 0.1 7.2 6 0 0 6 6 6 4 WD domain, G-beta repeat DUF1737 PF08410.10 KXS22169.1 - 0.012 15.4 0.0 0.029 14.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1737) RWD PF05773.22 KXS22169.1 - 0.079 13.3 0.0 0.21 11.9 0.0 1.7 1 0 0 1 1 1 0 RWD domain DZR PF12773.7 KXS22169.1 - 0.18 11.8 8.8 0.31 11.1 7.7 2.0 1 1 0 1 1 1 0 Double zinc ribbon zf-RING_2 PF13639.6 KXS22169.1 - 2 8.8 12.3 0.048 14.0 5.2 2.0 2 0 0 2 2 2 0 Ring finger domain PHD PF00628.29 KXS22169.1 - 2.2 8.2 8.9 0.51 10.3 4.3 2.2 2 0 0 2 2 2 0 PHD-finger zf-RING-like PF08746.11 KXS22169.1 - 3.5 8.0 7.5 9.7 6.6 7.5 1.8 1 0 0 1 1 1 0 RING-like domain zf-rbx1 PF12678.7 KXS22169.1 - 3.5 8.0 13.6 0.7 10.2 9.8 1.8 2 0 0 2 2 2 0 RING-H2 zinc finger domain HCNGP PF07818.13 KXS22170.1 - 1.7e-19 70.2 0.0 3e-19 69.5 0.0 1.4 1 0 0 1 1 1 1 HCNGP-like protein NUDE_C PF04880.13 KXS22171.1 - 0.13 12.8 1.8 0.18 12.3 1.8 1.2 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region DUF364 PF04016.12 KXS22172.1 - 0.04 13.5 0.0 0.22 11.1 0.0 2.0 1 1 0 1 1 1 0 Putative heavy-metal chelation Methyltransf_23 PF13489.6 KXS22172.1 - 0.1 12.5 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain FAD_binding_3 PF01494.19 KXS22174.1 - 3.7e-24 85.6 0.3 1.5e-13 50.7 0.0 2.9 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.24 KXS22174.1 - 3e-07 30.4 0.0 3.2e-05 23.7 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KXS22174.1 - 3.5e-05 23.2 0.1 5.2e-05 22.6 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 KXS22174.1 - 9.4e-05 22.5 0.0 0.00017 21.7 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_8 PF13450.6 KXS22174.1 - 0.00027 21.1 0.0 0.00061 20.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KXS22174.1 - 0.0003 20.1 0.0 0.00048 19.4 0.0 1.2 1 0 0 1 1 1 1 Thi4 family TrkA_N PF02254.18 KXS22174.1 - 0.00036 20.8 0.0 0.00062 20.0 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain Pyr_redox_2 PF07992.14 KXS22174.1 - 0.001 18.4 0.0 0.0015 17.8 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXS22174.1 - 0.002 17.3 0.0 0.003 16.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 KXS22174.1 - 0.0034 16.5 0.1 0.016 14.3 0.0 1.9 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox PF00070.27 KXS22174.1 - 0.0047 17.5 0.1 0.017 15.6 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXS22174.1 - 0.0051 15.6 0.0 0.0074 15.0 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein Trp_halogenase PF04820.14 KXS22174.1 - 0.053 12.4 0.1 0.66 8.8 0.0 2.0 2 0 0 2 2 2 0 Tryptophan halogenase Ank_2 PF12796.7 KXS22175.1 - 5.1e-09 36.6 0.1 0.0029 18.2 0.0 3.6 2 2 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXS22175.1 - 8.2e-09 35.6 1.3 0.002 18.4 0.1 4.5 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXS22175.1 - 1.8e-08 33.9 1.5 0.024 15.2 0.1 4.4 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 KXS22175.1 - 3.5e-08 33.5 0.6 0.37 11.3 0.0 4.4 3 1 1 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 KXS22175.1 - 6.2e-08 33.0 1.5 0.71 10.5 0.0 4.4 3 1 2 5 5 5 3 Ankyrin repeats (many copies) HATPase_c PF02518.26 KXS22176.1 - 2.3e-31 108.6 0.0 4.7e-31 107.6 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KXS22176.1 - 6.3e-17 61.8 0.1 4e-15 55.9 0.1 2.5 1 1 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 KXS22176.1 - 4.8e-16 58.5 0.0 2e-15 56.6 0.0 2.1 1 1 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 KXS22176.1 - 0.0071 16.2 0.0 0.017 14.9 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase RP-C PF03428.13 KXS22176.1 - 0.05 13.3 2.5 24 4.5 0.0 3.2 2 1 1 3 3 3 0 Replication protein C N-terminal domain DUF1397 PF07165.11 KXS22176.1 - 0.24 10.8 0.1 0.49 9.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1397) Acetyltransf_9 PF13527.7 KXS22177.1 - 4.4e-06 26.8 0.2 8.8e-06 25.8 0.1 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXS22177.1 - 0.053 13.9 0.0 0.092 13.2 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Glyco_transf_8 PF01501.20 KXS22178.1 - 1.7e-15 57.3 0.0 3.2e-15 56.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 8 SH3_9 PF14604.6 KXS22178.1 - 0.00016 21.5 0.0 0.00039 20.2 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXS22178.1 - 0.0011 18.6 0.0 0.0024 17.4 0.0 1.6 1 0 0 1 1 1 1 SH3 domain Nucleotid_trans PF03407.16 KXS22178.1 - 0.024 14.6 0.0 0.047 13.6 0.0 1.4 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase DUF2570 PF10828.8 KXS22178.1 - 9.7 6.1 12.5 0.91 9.4 0.2 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2570) PXB PF12828.7 KXS22180.1 - 0.1 12.6 1.1 0.81 9.7 0.2 2.0 1 1 0 2 2 2 0 PX-associated AMP-binding PF00501.28 KXS22181.1 - 2.9e-85 286.4 0.0 3.8e-85 286.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXS22181.1 - 3.6e-14 53.5 0.1 6.7e-14 52.6 0.1 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DNA_pol_B_exo1 PF03104.19 KXS22182.1 - 0.0007 18.8 0.0 0.0012 18.1 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 KXS22183.1 - 1.2e-98 330.8 0.0 1.6e-98 330.4 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B zf-C4pol PF14260.6 KXS22183.1 - 7.7e-16 58.3 6.5 1.3e-15 57.6 6.5 1.4 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_exo1 PF03104.19 KXS22183.1 - 6.3e-14 51.8 0.0 1.1e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain RecR PF02132.15 KXS22183.1 - 0.0066 16.0 2.6 0.018 14.6 2.6 1.7 1 0 0 1 1 1 1 RecR protein zn-ribbon_14 PF16503.5 KXS22183.1 - 0.4 10.2 2.2 0.85 9.2 2.2 1.5 1 0 0 1 1 1 0 Zinc-ribbon AMP-binding PF00501.28 KXS22184.1 - 5.6e-64 216.3 0.0 6.9e-64 216.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXS22184.1 - 2.7e-14 53.9 0.2 5.1e-14 53.0 0.2 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain EF-hand_4 PF12763.7 KXS22185.1 - 2.6e-28 98.0 0.0 6.1e-11 42.2 0.0 3.3 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.6 KXS22185.1 - 0.0016 18.8 0.0 0.016 15.6 0.0 2.5 3 1 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 KXS22185.1 - 0.0052 16.2 0.0 11 5.8 0.0 4.6 5 0 0 5 5 5 1 EF hand EF-hand_6 PF13405.6 KXS22185.1 - 0.01 15.7 0.0 30 4.9 0.0 3.9 4 0 0 4 4 4 0 EF-hand domain UBA_4 PF14555.6 KXS22185.1 - 0.012 15.4 0.0 0.056 13.3 0.0 2.1 2 0 0 2 2 2 0 UBA-like domain HBS1_N PF08938.10 KXS22185.1 - 0.21 11.9 1.1 0.33 11.3 0.1 1.9 2 0 0 2 2 2 0 HBS1 N-terminus CENP-F_leu_zip PF10473.9 KXS22185.1 - 3.2 7.8 33.2 0.57 10.2 14.3 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 WD40_alt PF14077.6 KXS22185.1 - 7.6 6.5 5.3 7.5 6.5 0.3 2.5 2 0 0 2 2 2 0 Alternative WD40 repeat motif FPP PF05911.11 KXS22185.1 - 9.1 4.3 27.4 1.2 7.2 7.5 2.0 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil DDE_Tnp_4 PF13359.6 KXS22186.1 - 5e-18 65.3 0.0 6.9e-18 64.8 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Peptidase_C78 PF07910.13 KXS22188.1 - 9.5e-37 126.5 0.0 1.3e-35 122.8 0.0 2.1 1 1 0 1 1 1 1 Peptidase family C78 GvpG PF05120.12 KXS22188.1 - 0.044 13.8 0.1 0.1 12.6 0.1 1.6 1 0 0 1 1 1 0 Gas vesicle protein G zf_UBZ PF18439.1 KXS22188.1 - 1.5 8.5 8.2 0.49 10.0 4.0 2.2 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Pkinase PF00069.25 KXS22189.1 - 6.3e-74 248.7 0.0 7.7e-74 248.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS22189.1 - 3.2e-35 121.7 0.0 4e-35 121.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXS22189.1 - 2.2e-07 30.0 0.4 5.1e-07 28.8 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 KXS22189.1 - 0.00023 20.6 0.0 0.00041 19.7 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 KXS22189.1 - 0.0062 15.9 0.0 0.01 15.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 KXS22189.1 - 0.042 13.4 0.0 0.069 12.7 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL NMO PF03060.15 KXS22190.1 - 1.6e-57 195.4 4.2 2.4e-57 194.8 4.2 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KXS22190.1 - 1.4e-13 50.6 3.2 1.4e-13 50.6 3.2 1.5 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KXS22190.1 - 6e-07 28.8 6.6 1.1e-06 28.0 6.6 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 KXS22190.1 - 0.0033 16.6 2.4 0.0078 15.4 2.4 1.6 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.15 KXS22191.1 - 2.3e-32 112.7 2.8 2.8e-32 112.4 2.8 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase FMN_dh PF01070.18 KXS22191.1 - 5.4e-06 25.7 3.8 7.3e-06 25.2 3.8 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 KXS22191.1 - 0.00054 19.1 7.4 0.00073 18.6 6.9 1.5 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain DUF1729 PF08354.10 KXS22191.1 - 0.0061 15.5 0.1 0.0061 15.5 0.1 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF1729) Glu_synthase PF01645.17 KXS22191.1 - 0.013 14.6 4.5 0.02 14.0 4.5 1.2 1 0 0 1 1 1 0 Conserved region in glutamate synthase DUF1667 PF07892.11 KXS22191.1 - 0.11 12.5 2.2 0.2 11.7 0.5 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1667) SET PF00856.28 KXS22192.1 - 5.2e-10 40.0 0.0 8.9e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 SET domain Ta0938 PF11494.8 KXS22192.1 - 0.093 13.0 0.0 0.21 11.9 0.0 1.5 1 0 0 1 1 1 0 Ta0938 PUF PF00806.19 KXS22193.1 - 1.7e-06 27.4 0.0 0.22 11.3 0.0 4.9 6 0 0 6 6 6 2 Pumilio-family RNA binding repeat Fibrillarin PF01269.17 KXS22194.1 - 1.2e-95 319.0 0.1 1.4e-95 318.7 0.1 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 KXS22194.1 - 4.1e-06 26.7 0.0 5.4e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltr_RsmB-F PF01189.17 KXS22194.1 - 0.0049 16.5 0.0 0.026 14.1 0.0 1.8 1 1 1 2 2 2 1 16S rRNA methyltransferase RsmB/F PCMT PF01135.19 KXS22194.1 - 0.0069 16.2 0.1 0.013 15.3 0.1 1.5 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.19 KXS22194.1 - 0.0081 16.3 0.0 0.012 15.7 0.0 1.3 1 1 0 1 1 1 1 FtsJ-like methyltransferase DREV PF05219.12 KXS22194.1 - 0.078 12.1 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Pkinase PF00069.25 KXS22195.1 - 3.6e-68 229.8 0.0 4.1e-68 229.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS22195.1 - 1.1e-36 126.4 0.0 1.4e-36 126.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXS22195.1 - 3.6e-08 33.1 0.0 5.3e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KXS22195.1 - 0.00035 20.6 0.2 0.00069 19.6 0.2 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KXS22195.1 - 0.0015 18.0 0.3 0.0038 16.6 0.4 1.7 2 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KXS22195.1 - 0.0024 16.9 0.1 0.0034 16.4 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 KXS22195.1 - 0.0027 16.6 0.0 0.0046 15.8 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 KXS22195.1 - 0.056 13.0 0.0 0.13 11.8 0.1 1.6 2 0 0 2 2 2 0 RIO1 family GRIM-19 PF06212.12 KXS22196.1 - 3.7e-28 98.1 0.0 1e-26 93.5 0.0 2.0 1 1 0 1 1 1 1 GRIM-19 protein GGACT PF06094.12 KXS22197.1 - 0.07 13.7 0.0 0.13 12.9 0.0 1.4 1 1 0 1 1 1 0 Gamma-glutamyl cyclotransferase, AIG2-like MtrD PF04207.12 KXS22197.1 - 0.096 12.4 0.1 0.14 11.9 0.1 1.2 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit D Glyoxalase PF00903.25 KXS22197.1 - 0.12 12.6 0.0 0.16 12.1 0.0 1.2 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily FAD_binding_3 PF01494.19 KXS22199.1 - 9.8e-25 87.5 0.0 7.8e-24 84.6 0.0 2.1 1 1 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KXS22199.1 - 2e-07 30.0 0.1 0.00015 20.6 0.1 2.1 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_2 PF07992.14 KXS22199.1 - 2.8e-07 30.1 1.2 5.7e-05 22.5 0.2 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KXS22199.1 - 5e-06 26.1 0.1 8.4e-06 25.4 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 KXS22199.1 - 5.7e-06 26.1 0.3 0.00065 19.4 0.2 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXS22199.1 - 9.8e-06 25.7 0.2 2.5e-05 24.4 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KXS22199.1 - 1.3e-05 24.5 0.9 2.3e-05 23.7 0.4 1.7 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.22 KXS22199.1 - 0.00014 21.1 0.4 0.00038 19.7 0.6 1.6 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KXS22199.1 - 0.00022 20.6 0.1 0.0025 17.1 0.2 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXS22199.1 - 0.004 17.2 0.3 0.87 9.6 0.1 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.17 KXS22199.1 - 0.0066 15.7 0.1 0.011 15.0 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Trp_halogenase PF04820.14 KXS22199.1 - 0.096 11.5 0.0 0.57 9.0 0.0 2.0 2 0 0 2 2 2 0 Tryptophan halogenase Pyr_redox PF00070.27 KXS22199.1 - 0.15 12.6 3.7 0.5 11.0 0.1 3.2 4 0 0 4 4 4 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KXS22199.1 - 0.15 11.0 0.2 0.8 8.7 0.1 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein SAPS PF04499.15 KXS22200.1 - 5.5 5.6 7.3 8.1 5.1 7.3 1.4 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Pox_Ag35 PF03286.14 KXS22200.1 - 7.4 6.3 20.3 2.8 7.7 15.8 2.2 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Acyl-CoA_dh_1 PF00441.24 KXS22201.1 - 7.8e-37 126.8 0.3 1.3e-36 126.1 0.3 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.28 KXS22201.1 - 3.3e-20 72.0 0.0 1e-19 70.5 0.0 1.9 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.19 KXS22201.1 - 4e-19 68.6 0.1 7.7e-19 67.7 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KXS22201.1 - 4.2e-12 46.7 0.0 1.1e-11 45.4 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KXS22201.1 - 9.8e-05 22.6 0.0 0.00018 21.8 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain VWA_2 PF13519.6 KXS22202.1 - 1.8e-09 38.2 0.0 2.5e-09 37.7 0.0 1.3 1 1 0 1 1 1 1 von Willebrand factor type A domain DUF1281 PF06924.11 KXS22203.1 - 0.097 12.2 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1281) DUF1699 PF08004.11 KXS22205.1 - 0.079 12.6 0.0 1 9.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1699) LRR_4 PF12799.7 KXS22205.1 - 0.37 11.3 1.7 1.4e+02 3.1 0.0 4.1 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) Abhydrolase_2 PF02230.16 KXS22206.1 - 1.6e-47 162.1 0.0 1.9e-47 161.9 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 KXS22206.1 - 1.2e-05 24.7 0.0 0.0027 17.0 0.0 2.9 2 1 1 3 3 3 1 Serine aminopeptidase, S33 FSH1 PF03959.13 KXS22206.1 - 1.4e-05 24.9 0.0 4.4e-05 23.3 0.0 1.7 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 KXS22206.1 - 0.00018 22.2 0.1 0.00023 21.9 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KXS22206.1 - 0.0012 18.4 0.0 0.011 15.2 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family Esterase_phd PF10503.9 KXS22206.1 - 0.012 15.2 0.0 0.24 10.9 0.0 2.1 1 1 0 1 1 1 0 Esterase PHB depolymerase Abhydrolase_3 PF07859.13 KXS22206.1 - 0.03 14.2 0.0 0.039 13.8 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold BAAT_C PF08840.11 KXS22206.1 - 0.034 14.0 0.0 0.26 11.2 0.0 2.0 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Cutinase PF01083.22 KXS22206.1 - 0.039 13.9 0.0 0.053 13.5 0.0 1.2 1 0 0 1 1 1 0 Cutinase DLH PF01738.18 KXS22206.1 - 0.043 13.4 0.0 0.073 12.6 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family HATPase_c PF02518.26 KXS22207.1 - 5.7e-30 104.1 0.0 1.9e-29 102.4 0.0 2.0 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KXS22207.1 - 7.2e-23 80.9 0.1 1.5e-22 79.9 0.1 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 KXS22207.1 - 7.5e-20 70.7 0.1 2.1e-19 69.3 0.1 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.12 KXS22207.1 - 0.068 13.5 0.1 1.2 9.5 0.0 2.7 3 0 0 3 3 3 0 PAS fold HATPase_c_3 PF13589.6 KXS22207.1 - 0.11 12.3 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF2982 PF11201.8 KXS22207.1 - 0.12 11.9 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2982) Cys_Met_Meta_PP PF01053.20 KXS22208.1 - 3.9e-131 437.1 0.0 4.9e-131 436.8 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Met_gamma_lyase PF06838.11 KXS22208.1 - 0.0017 17.0 0.0 0.0024 16.5 0.0 1.1 1 0 0 1 1 1 1 Methionine gamma-lyase GDC-P PF02347.16 KXS22208.1 - 0.21 10.4 0.0 0.31 9.8 0.0 1.2 1 0 0 1 1 1 0 Glycine cleavage system P-protein DUF1505 PF07403.11 KXS22209.1 - 0.0069 16.6 2.0 0.014 15.5 2.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1505) Beta-lactamase PF00144.24 KXS22210.1 - 2.2e-24 86.3 0.1 3.2e-24 85.8 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase Extensin_2 PF04554.13 KXS22211.1 - 0.02 14.9 2.3 0.046 13.8 2.3 1.5 1 0 0 1 1 1 0 Extensin-like region AOX PF01786.17 KXS22212.1 - 2.8e-83 278.8 1.9 3.5e-83 278.4 1.9 1.1 1 0 0 1 1 1 1 Alternative oxidase EMG1 PF03587.14 KXS22213.1 - 4.3e-71 238.6 0.0 5.1e-71 238.3 0.0 1.1 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase MAPEG PF01124.18 KXS22214.1 - 6.7e-10 39.0 3.5 1.8e-09 37.6 3.5 1.8 1 1 0 1 1 1 1 MAPEG family Glyco_hydro_18 PF00704.28 KXS22215.1 - 6.3e-12 45.9 0.1 1.9e-11 44.3 0.1 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_16 PF00722.21 KXS22215.1 - 9.3e-08 31.7 0.0 0.00027 20.4 0.0 2.6 2 0 0 2 2 2 2 Glycosyl hydrolases family 16 MTCP1 PF08991.10 KXS22216.1 - 2.7e-11 43.5 9.8 3.3e-11 43.2 9.8 1.2 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type CHCH PF06747.13 KXS22216.1 - 0.047 13.8 8.8 0.22 11.7 4.4 2.2 1 1 1 2 2 2 0 CHCH domain GCK PF07802.11 KXS22216.1 - 2.6 8.5 9.9 2.1 8.8 1.3 2.7 1 1 2 3 3 3 0 GCK domain F-box-like PF12937.7 KXS22217.1 - 0.00046 20.0 0.4 0.0014 18.5 0.4 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXS22217.1 - 0.0065 16.3 0.9 0.035 14.0 0.3 2.5 2 0 0 2 2 2 1 F-box domain Swi5 PF07061.11 KXS22218.1 - 1.4e-16 60.3 0.0 2.4e-16 59.6 0.0 1.4 1 0 0 1 1 1 1 Swi5 Bestrophin PF01062.21 KXS22219.1 - 1.3e-37 129.8 0.2 2.3e-37 129.0 0.2 1.3 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Cu-oxidase_2 PF07731.14 KXS22220.1 - 1e-13 51.2 7.7 8.9e-09 35.2 3.0 3.4 2 2 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KXS22220.1 - 1.4e-10 41.2 3.3 8.5e-10 38.7 0.7 2.7 2 1 0 2 2 2 1 Multicopper oxidase FTR1 PF03239.14 KXS22221.1 - 1.2e-28 100.2 0.5 6.9e-18 64.8 0.3 2.0 2 0 0 2 2 2 2 Iron permease FTR1 family BacA PF02673.18 KXS22221.1 - 0.011 15.5 0.1 0.015 15.1 0.1 1.3 1 0 0 1 1 1 0 Bacitracin resistance protein BacA Sbt_1 PF05982.12 KXS22221.1 - 0.028 13.7 0.9 0.039 13.2 0.9 1.2 1 0 0 1 1 1 0 Na+-dependent bicarbonate transporter superfamily Virul_fac_BrkB PF03631.15 KXS22221.1 - 0.061 12.9 4.0 0.097 12.3 4.0 1.2 1 0 0 1 1 1 0 Virulence factor BrkB UPF0016 PF01169.19 KXS22221.1 - 0.069 13.5 1.5 0.17 12.2 1.5 1.7 1 0 0 1 1 1 0 Uncharacterized protein family UPF0016 Coronavirus_5 PF05528.11 KXS22221.1 - 0.094 12.7 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Coronavirus gene 5 protein CrgA PF06781.12 KXS22221.1 - 0.25 11.4 1.2 1.4 9.0 0.6 2.3 2 0 0 2 2 2 0 Cell division protein CrgA PP2C PF00481.21 KXS22222.1 - 1.9e-05 24.4 0.0 0.058 13.0 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C RdRP PF05183.12 KXS22224.1 - 3.3e-170 567.6 0.0 4.1e-170 567.3 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase RRM_1 PF00076.22 KXS22224.1 - 1e-06 28.4 0.0 8.4e-06 25.5 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Beta-lactamase PF00144.24 KXS22225.1 - 1.3e-36 126.6 0.0 2.8e-36 125.4 0.0 1.5 1 1 0 1 1 1 1 Beta-lactamase Pro_isomerase PF00160.21 KXS22226.1 - 2.3e-48 164.5 0.0 2.5e-48 164.3 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Reeler PF02014.16 KXS22227.1 - 3e-07 31.2 0.1 3e-07 31.2 0.1 1.8 2 0 0 2 2 2 1 Reeler domain SF1-HH PF16275.5 KXS22228.1 - 3.8e-34 117.4 1.0 8.2e-34 116.3 1.0 1.6 1 0 0 1 1 1 1 Splicing factor 1 helix-hairpin domain zf-CCHC PF00098.23 KXS22228.1 - 1.4e-10 40.7 10.2 3.5e-05 23.7 2.7 2.3 2 0 0 2 2 2 2 Zinc knuckle KH_1 PF00013.29 KXS22228.1 - 2.4e-09 36.9 0.1 4.9e-09 35.9 0.1 1.5 1 0 0 1 1 1 1 KH domain zf-CCHC_3 PF13917.6 KXS22228.1 - 0.002 18.0 1.0 0.002 18.0 1.0 2.1 1 1 1 2 2 2 1 Zinc knuckle zf-CCHC_4 PF14392.6 KXS22228.1 - 0.08 12.7 8.1 0.29 10.9 0.5 2.5 2 0 0 2 2 2 0 Zinc knuckle DnaJ_CXXCXGXG PF00684.19 KXS22228.1 - 0.12 12.7 3.1 0.24 11.8 3.1 1.4 1 0 0 1 1 1 0 DnaJ central domain zf-CCHC_6 PF15288.6 KXS22228.1 - 0.72 9.7 4.9 0.47 10.3 0.9 2.5 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_2 PF13696.6 KXS22228.1 - 2 8.3 11.6 0.25 11.2 2.6 2.5 2 0 0 2 2 2 0 Zinc knuckle Lipase_3 PF01764.25 KXS22229.1 - 3.6e-17 62.5 0.0 5.6e-17 61.9 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) O-FucT PF10250.9 KXS22231.1 - 5e-05 23.2 0.0 6.9e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase DUF3431 PF11913.8 KXS22232.1 - 3.4e-09 36.8 0.0 7.4e-09 35.7 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3431) PX PF00787.24 KXS22234.1 - 4.9e-16 58.7 0.0 5.6e-16 58.5 0.0 1.1 1 0 0 1 1 1 1 PX domain Exo_endo_phos PF03372.23 KXS22235.1 - 1e-13 51.3 3.7 2.7e-13 50.0 0.0 2.6 2 1 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family PhyH PF05721.13 KXS22236.1 - 3.3e-11 43.9 0.0 7.1e-09 36.2 0.1 2.1 2 0 0 2 2 2 2 Phytanoyl-CoA dioxygenase (PhyH) Ank_2 PF12796.7 KXS22237.1 - 2e-19 69.9 0.5 1.4e-08 35.2 0.1 2.5 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXS22237.1 - 1.4e-18 67.0 2.0 0.00011 22.7 0.0 5.1 1 1 5 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXS22237.1 - 3.8e-15 54.5 0.1 0.016 15.7 0.0 6.0 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 KXS22237.1 - 2e-13 50.3 2.8 0.00089 19.5 0.1 5.2 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 KXS22237.1 - 3.2e-12 46.3 4.8 0.72 10.4 0.0 5.9 6 0 0 6 6 6 4 Ankyrin repeat BCDHK_Adom3 PF10436.9 KXS22238.1 - 3.3e-30 105.1 0.0 5.8e-30 104.3 0.0 1.4 1 1 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KXS22238.1 - 7.8e-11 42.5 0.0 2.7e-10 40.7 0.0 1.8 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KXS22238.1 - 0.036 13.9 0.0 0.058 13.2 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Chromate_transp PF02417.15 KXS22240.1 - 3.7e-53 179.9 45.8 7.1e-33 114.0 15.8 2.4 3 0 0 3 3 3 2 Chromate transporter EphA2_TM PF14575.6 KXS22241.1 - 0.19 12.6 0.0 0.19 12.6 0.0 1.1 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Phage_holin_2_1 PF04971.12 KXS22242.1 - 0.084 12.9 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 Bacteriophage P21 holin S DUF1138 PF06592.13 KXS22242.1 - 0.22 11.6 0.1 0.22 11.6 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1138) COX6C PF02937.15 KXS22242.1 - 0.26 11.5 0.6 29 4.9 0.1 2.2 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIc DAP10 PF07213.11 KXS22243.1 - 0.038 13.9 0.0 0.071 13.1 0.0 1.4 1 0 0 1 1 1 0 DAP10 membrane protein Orthoreo_P10 PF07204.11 KXS22244.1 - 0.0061 16.5 0.5 0.11 12.5 0.1 2.1 2 0 0 2 2 2 1 Orthoreovirus membrane fusion protein p10 EphA2_TM PF14575.6 KXS22244.1 - 0.0081 17.0 1.3 0.0087 16.9 0.0 1.7 2 1 1 3 3 3 1 Ephrin type-A receptor 2 transmembrane domain Shisa PF13908.6 KXS22244.1 - 0.018 15.3 0.6 0.028 14.7 0.6 1.5 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator Mucin PF01456.17 KXS22244.1 - 0.032 14.2 0.1 0.032 14.2 0.1 2.3 1 1 1 2 2 2 0 Mucin-like glycoprotein Herpes_gE PF02480.16 KXS22244.1 - 0.076 11.7 1.0 0.14 10.8 0.3 1.6 1 1 1 2 2 2 0 Alphaherpesvirus glycoprotein E MLANA PF14991.6 KXS22244.1 - 0.11 12.8 0.4 0.27 11.5 0.4 1.5 1 1 0 1 1 1 0 Protein melan-A TMEM51 PF15345.6 KXS22244.1 - 0.12 12.2 0.1 0.12 12.2 0.1 1.6 2 1 0 2 2 2 0 Transmembrane protein 51 LapA_dom PF06305.11 KXS22244.1 - 0.19 11.6 0.9 0.35 10.7 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain TMEM52 PF14979.6 KXS22244.1 - 0.94 9.4 5.4 0.53 10.2 0.4 2.3 2 0 0 2 2 2 0 Transmembrane 52 Ank_2 PF12796.7 KXS22249.1 - 2.3e-45 153.1 0.4 3.6e-12 46.7 0.0 5.5 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXS22249.1 - 2e-38 126.0 3.0 6.5e-05 23.0 0.0 10.0 9 1 1 10 10 10 8 Ankyrin repeat Ank_4 PF13637.6 KXS22249.1 - 1.3e-34 118.1 0.3 2e-06 28.3 0.0 7.1 6 1 1 7 7 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXS22249.1 - 5.4e-26 90.3 2.9 0.00014 22.1 0.0 7.2 4 3 4 8 8 8 5 Ankyrin repeats (many copies) Ank PF00023.30 KXS22249.1 - 3.9e-25 87.2 2.4 0.00056 20.2 0.2 8.5 9 0 0 9 9 9 6 Ankyrin repeat ScdA_N PF04405.14 KXS22249.1 - 0.054 13.2 0.1 0.85 9.3 0.0 3.0 3 0 0 3 3 3 0 Domain of Unknown function (DUF542) p450 PF00067.22 KXS22250.1 - 1.7e-31 109.5 0.0 2.4e-31 109.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KXS22251.1 - 5.5e-32 111.1 0.0 6.7e-32 110.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_11 PF08241.12 KXS22255.1 - 5.8e-07 30.1 0.1 1.6e-06 28.7 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXS22255.1 - 6.9e-06 26.7 0.1 4.1e-05 24.2 0.1 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXS22255.1 - 6e-05 22.9 0.0 8.4e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXS22255.1 - 0.0056 17.4 0.0 0.012 16.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Acetyltransf_1 PF00583.25 KXS22256.1 - 3.4e-14 53.1 0.0 4.4e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXS22256.1 - 1.1e-10 41.6 0.0 1.4e-10 41.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXS22256.1 - 1.6e-10 41.3 0.0 2.2e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KXS22256.1 - 3.7e-06 27.0 0.0 5.5e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 KXS22256.1 - 7.5e-06 25.8 0.0 1.2e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_6 PF13480.7 KXS22256.1 - 0.021 15.0 0.7 0.03 14.5 0.7 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PanZ PF12568.8 KXS22256.1 - 0.034 13.9 0.0 0.043 13.5 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_3 PF13302.7 KXS22256.1 - 0.07 13.8 0.0 0.085 13.5 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KXS22256.1 - 0.089 12.9 0.0 0.092 12.9 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Dicty_CAR PF05462.11 KXS22257.1 - 5.9e-06 25.6 12.4 0.00075 18.7 0.5 2.3 2 1 0 2 2 2 2 Slime mold cyclic AMP receptor 7tm_1 PF00001.21 KXS22257.1 - 1.6e-05 24.3 6.8 2.6e-05 23.7 6.8 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Git3 PF11710.8 KXS22257.1 - 0.00019 21.3 6.0 0.00035 20.4 6.0 1.5 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 GPR_Gpa2_C PF11970.8 KXS22257.1 - 0.015 15.3 0.7 0.015 15.3 0.7 2.1 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 C-term Bac_export_2 PF01312.19 KXS22257.1 - 0.33 10.1 1.6 0.44 9.7 1.6 1.2 1 0 0 1 1 1 0 FlhB HrpN YscU SpaS Family Diphthami_syn_2 PF01902.17 KXS22258.1 - 6.1e-31 107.6 0.0 1.3e-26 93.5 0.0 3.1 2 1 0 3 3 3 2 Diphthamide synthase Ribonuc_L-PSP PF01042.21 KXS22258.1 - 4.4e-15 55.7 0.0 1.9e-08 34.3 0.0 2.5 2 0 0 2 2 2 2 Endoribonuclease L-PSP ZT_dimer PF16916.5 KXS22258.1 - 0.17 12.0 0.6 0.5 10.5 0.1 1.9 2 0 0 2 2 2 0 Dimerisation domain of Zinc Transporter MIG-14_Wnt-bd PF06664.12 KXS22259.1 - 0.021 14.1 0.1 0.021 14.1 0.1 2.4 2 1 1 3 3 3 0 Wnt-binding factor required for Wnt secretion DUF2062 PF09835.9 KXS22259.1 - 0.069 13.0 5.0 0.13 12.1 3.6 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2062) GMC_oxred_N PF00732.19 KXS22261.1 - 1e-52 179.4 0.0 1.3e-52 179.0 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXS22261.1 - 3.1e-41 141.2 0.0 5.1e-41 140.6 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase RRM_1 PF00076.22 KXS22262.1 - 3.2e-13 49.3 0.0 6.8e-13 48.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AhpC-TSA PF00578.21 KXS22263.1 - 2.9e-07 30.5 0.0 6.7e-07 29.3 0.0 1.6 1 1 0 1 1 1 1 AhpC/TSA family AhpC-TSA_2 PF13911.6 KXS22263.1 - 0.0007 19.7 0.0 0.0016 18.5 0.0 1.6 2 0 0 2 2 2 1 AhpC/TSA antioxidant enzyme Redoxin PF08534.10 KXS22263.1 - 0.0012 18.6 0.0 0.0052 16.5 0.0 1.8 2 0 0 2 2 2 1 Redoxin DUF2340 PF10209.9 KXS22264.1 - 1.3e-41 141.9 0.0 1.4e-41 141.7 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2340) Blt1 PF12754.7 KXS22264.1 - 0.035 14.4 0.1 0.042 14.2 0.1 1.1 1 0 0 1 1 1 0 Blt1 N-terminal domain DUF4252 PF14060.6 KXS22264.1 - 0.085 12.8 0.1 0.11 12.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4252) SIR2 PF02146.17 KXS22265.1 - 7.6e-44 149.7 0.0 1.2e-43 149.1 0.0 1.3 1 1 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 KXS22265.1 - 0.016 14.9 0.0 1.7 8.4 0.0 2.4 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain F-box-like PF12937.7 KXS22266.1 - 4.4e-06 26.5 0.4 9.8e-06 25.4 0.4 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXS22266.1 - 0.00057 19.7 0.1 0.0012 18.6 0.1 1.6 1 0 0 1 1 1 1 F-box domain Phage_holin_5_2 PF16079.5 KXS22267.1 - 0.046 14.1 1.0 0.067 13.5 0.9 1.3 1 1 0 1 1 1 0 Phage holin family Hol44, in holin superfamily V SSXRD PF09514.10 KXS22267.1 - 0.062 12.9 0.3 0.12 12.0 0.3 1.4 1 0 0 1 1 1 0 SSXRD motif DUF4079 PF13301.6 KXS22267.1 - 0.12 12.5 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4079) TRI12 PF06609.13 KXS22267.1 - 0.17 10.3 0.1 0.2 10.0 0.1 1.0 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) Col_cuticle_N PF01484.17 KXS22267.1 - 3.1 7.9 4.3 0.85 9.7 1.0 1.7 2 0 0 2 2 2 0 Nematode cuticle collagen N-terminal domain MHYT PF03707.16 KXS22268.1 - 0.033 14.4 0.1 0.033 14.4 0.1 2.0 2 0 0 2 2 2 0 Bacterial signalling protein N terminal repeat DoxX_3 PF13781.6 KXS22268.1 - 0.083 13.5 0.2 0.14 12.8 0.2 1.3 1 0 0 1 1 1 0 DoxX-like family DUF4381 PF14316.6 KXS22268.1 - 0.098 12.9 0.2 0.2 11.9 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Tad PF13400.6 KXS22268.1 - 0.098 13.0 0.7 0.098 13.0 0.7 1.9 2 0 0 2 2 2 0 Putative Flp pilus-assembly TadE/G-like Gram_pos_anchor PF00746.21 KXS22268.1 - 0.19 11.7 0.2 0.37 10.8 0.2 1.5 1 0 0 1 1 1 0 LPXTG cell wall anchor motif DUF2076 PF09849.9 KXS22268.1 - 4.9 7.1 13.4 6.5 6.7 13.4 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) DIOX_N PF14226.6 KXS22269.1 - 9.4e-19 68.3 0.0 2.2e-18 67.1 0.0 1.6 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KXS22269.1 - 4.1e-11 43.3 0.0 6.9e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Pec_lyase_C PF00544.19 KXS22270.1 - 1.4e-09 37.9 8.9 1.1e-07 31.6 8.9 2.2 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 KXS22270.1 - 0.00013 21.9 7.0 0.00057 19.8 6.8 2.0 1 1 0 1 1 1 1 Right handed beta helix region Aa_trans PF01490.18 KXS22271.1 - 4.1e-26 91.6 10.8 4.1e-26 91.6 10.8 1.4 2 0 0 2 2 2 1 Transmembrane amino acid transporter protein zf-C3HC4_3 PF13920.6 KXS22273.1 - 5.5e-12 45.4 8.1 1.2e-11 44.2 8.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KXS22273.1 - 6.2e-07 29.2 8.1 1.5e-06 28.0 8.1 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KXS22273.1 - 8.7e-05 22.4 8.2 0.00019 21.3 8.2 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 KXS22273.1 - 0.00031 21.0 10.3 0.00087 19.6 10.3 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KXS22273.1 - 0.063 13.2 9.9 0.16 11.9 9.9 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_14 PF17978.1 KXS22273.1 - 0.065 13.7 2.1 0.18 12.3 2.1 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_2 PF13923.6 KXS22273.1 - 0.12 12.2 10.4 0.28 11.0 10.4 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Chorion_2 PF03964.15 KXS22273.1 - 0.24 12.2 2.8 0.61 11.0 2.8 1.7 1 0 0 1 1 1 0 Chorion family 2 zf-P11 PF03854.14 KXS22273.1 - 1.9 8.2 10.7 0.63 9.8 5.5 2.5 2 0 0 2 2 2 0 P-11 zinc finger LysM PF01476.20 KXS22275.1 - 1.1e-11 44.6 0.0 1.7e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 LysM domain HemX PF04375.14 KXS22275.1 - 0.34 10.2 1.3 0.47 9.7 1.3 1.1 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase adh_short PF00106.25 KXS22276.1 - 1.4e-46 158.4 0.0 1.8e-46 158.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXS22276.1 - 2.7e-35 122.0 0.0 3.4e-35 121.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXS22276.1 - 4.4e-10 39.8 0.0 6.9e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXS22276.1 - 1e-06 28.4 0.1 2.2e-06 27.3 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Glyco_tranf_2_3 PF13641.6 KXS22276.1 - 7.9e-05 22.6 0.1 0.00012 22.0 0.1 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 GDP_Man_Dehyd PF16363.5 KXS22276.1 - 0.00011 21.7 0.0 0.00017 21.1 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KXS22276.1 - 0.035 14.0 0.1 0.047 13.6 0.1 1.3 1 0 0 1 1 1 0 NAD(P)H-binding DUF1729 PF08354.10 KXS22276.1 - 0.093 11.6 0.0 0.13 11.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1729) Esterase PF00756.20 KXS22277.1 - 7.8e-46 156.7 0.0 9.5e-46 156.5 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 KXS22277.1 - 1.1e-06 28.3 0.0 1.4e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KXS22277.1 - 1.7e-06 27.5 0.0 1e-05 24.9 0.0 1.9 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 KXS22277.1 - 3.8e-06 26.9 0.0 2e-05 24.5 0.0 2.2 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase PAF-AH_p_II PF03403.13 KXS22277.1 - 0.0005 18.7 0.0 0.00071 18.2 0.0 1.1 1 0 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II DUF1057 PF06342.12 KXS22277.1 - 0.00062 18.9 0.0 0.00092 18.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Abhydrolase_1 PF00561.20 KXS22277.1 - 0.0017 18.0 0.0 0.0027 17.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXS22277.1 - 0.0077 16.9 0.0 0.0086 16.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 KXS22277.1 - 0.036 13.6 0.1 0.095 12.2 0.1 1.9 1 1 0 1 1 1 0 Dienelactone hydrolase family Lipase_3 PF01764.25 KXS22277.1 - 0.048 13.5 0.0 0.09 12.6 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Chlorophyllase2 PF12740.7 KXS22277.1 - 0.05 12.5 0.0 0.083 11.8 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Chlorophyllase PF07224.11 KXS22277.1 - 0.086 11.8 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Ras PF00071.22 KXS22278.1 - 2.9e-66 222.1 0.6 3.3e-66 221.9 0.6 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXS22278.1 - 1.2e-36 125.6 0.1 1.9e-36 124.9 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXS22278.1 - 3.1e-17 62.6 0.1 3.8e-17 62.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KXS22278.1 - 3.1e-07 30.4 0.4 0.0056 16.6 0.1 2.3 1 1 1 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 KXS22278.1 - 2.2e-06 27.4 0.3 5.2e-06 26.1 0.1 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KXS22278.1 - 3.5e-06 26.5 0.0 4.2e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KXS22278.1 - 1.5e-05 25.0 0.0 9.7e-05 22.4 0.0 1.9 1 1 1 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.10 KXS22278.1 - 5.2e-05 22.8 0.0 7.9e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 KXS22278.1 - 0.00033 20.2 0.1 0.0041 16.6 0.1 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA PF00004.29 KXS22278.1 - 0.0037 17.7 0.1 0.51 10.8 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KXS22278.1 - 0.0096 16.3 0.0 0.015 15.7 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain ATP_bind_1 PF03029.17 KXS22278.1 - 0.01 15.6 0.1 0.026 14.3 0.0 1.6 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 KXS22278.1 - 0.019 15.2 0.0 0.034 14.4 0.0 1.5 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KXS22278.1 - 0.034 14.7 0.0 0.068 13.7 0.0 1.6 1 1 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 KXS22278.1 - 0.05 13.3 0.0 0.15 11.8 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_5 PF07728.14 KXS22278.1 - 0.058 13.4 0.0 0.091 12.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Septin PF00735.18 KXS22278.1 - 0.066 12.5 0.1 0.16 11.2 0.0 1.6 2 1 0 2 2 2 0 Septin AAA_7 PF12775.7 KXS22278.1 - 0.077 12.5 0.0 0.18 11.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region TniB PF05621.11 KXS22278.1 - 0.08 12.3 0.0 0.2 11.0 0.0 1.6 2 0 0 2 2 2 0 Bacterial TniB protein PduV-EutP PF10662.9 KXS22278.1 - 0.097 12.4 0.1 0.78 9.5 0.1 2.3 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Dioxygenase_C PF00775.21 KXS22279.1 - 1.7e-42 144.9 0.0 3.5e-42 143.9 0.0 1.5 2 0 0 2 2 2 1 Dioxygenase Dioxygenase_N PF04444.14 KXS22279.1 - 9.1e-21 73.5 0.1 1.4e-20 72.9 0.1 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 KXS22279.1 - 1.2e-05 25.5 0.1 0.00014 22.1 0.0 2.7 3 1 1 4 4 4 1 Carboxypeptidase regulatory-like domain EnY2 PF10163.9 KXS22281.1 - 6.9e-17 61.6 0.7 7.7e-17 61.5 0.7 1.0 1 0 0 1 1 1 1 Transcription factor e(y)2 TetR_N PF00440.23 KXS22281.1 - 0.029 14.2 0.1 0.069 13.0 0.0 1.6 2 0 0 2 2 2 0 Bacterial regulatory proteins, tetR family PLU-1 PF08429.11 KXS22281.1 - 0.073 12.2 0.2 0.082 12.1 0.2 1.0 1 0 0 1 1 1 0 PLU-1-like protein PCP_red PF08369.10 KXS22281.1 - 0.27 11.5 1.8 7.1 6.9 0.2 2.2 1 1 1 2 2 2 0 Proto-chlorophyllide reductase 57 kD subunit LSM PF01423.22 KXS22282.1 - 2.6e-20 71.8 0.1 3.9e-20 71.3 0.1 1.2 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 KXS22282.1 - 0.073 12.7 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Hfq protein Ribosomal_L27e PF01777.18 KXS22283.1 - 4.9e-36 123.0 3.0 8e-36 122.3 3.0 1.3 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 KXS22283.1 - 9.4e-05 22.2 0.7 0.00017 21.4 0.7 1.5 1 0 0 1 1 1 1 KOW motif GST_N_3 PF13417.6 KXS22284.1 - 2.4e-14 53.5 0.1 5.1e-14 52.4 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KXS22284.1 - 1.3e-06 28.7 0.0 2.4e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KXS22284.1 - 6.1e-06 26.5 0.0 1.9e-05 24.9 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KXS22284.1 - 8.6e-06 25.7 0.0 3.1e-05 23.9 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KXS22284.1 - 0.007 16.5 0.0 0.014 15.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 KXS22284.1 - 0.081 13.2 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein HATPase_c PF02518.26 KXS22285.1 - 1.5e-33 115.6 0.0 3.5e-33 114.4 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KXS22285.1 - 3.4e-18 65.4 0.2 1.4e-17 63.4 0.0 2.3 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain Response_reg PF00072.24 KXS22285.1 - 1.5e-17 63.8 0.2 2.9e-17 62.8 0.2 1.5 1 0 0 1 1 1 1 Response regulator receiver domain Pyr_redox_2 PF07992.14 KXS22286.1 - 1e-08 34.8 0.0 1.7e-06 27.5 0.0 2.9 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXS22286.1 - 3e-06 27.3 0.0 5.4e-05 23.3 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KXS22286.1 - 8.9e-05 21.9 0.1 0.0014 18.0 0.0 2.6 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KXS22286.1 - 0.00012 20.6 0.1 0.0069 14.9 0.1 2.5 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox PF00070.27 KXS22286.1 - 0.0023 18.5 0.0 0.086 13.4 0.1 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 KXS22286.1 - 0.004 17.2 0.0 0.067 13.3 0.0 2.5 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 KXS22286.1 - 0.11 11.9 0.0 0.45 9.8 0.0 1.9 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain SH3_9 PF14604.6 KXS22287.1 - 1.4e-05 24.9 0.0 2.2e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXS22287.1 - 0.00014 21.4 0.1 0.00028 20.4 0.1 1.5 1 1 0 1 1 1 1 SH3 domain MitMem_reg PF13012.6 KXS22288.1 - 2.9e-36 124.3 0.5 4.9e-36 123.6 0.5 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 KXS22288.1 - 2.8e-33 114.4 0.6 1e-32 112.6 0.0 2.0 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease PVL_ORF50 PF07768.11 KXS22288.1 - 0.14 12.5 4.8 0.46 10.8 4.8 1.8 1 0 0 1 1 1 0 PVL ORF-50-like family COX16 PF14138.6 KXS22288.1 - 0.2 12.2 1.7 0.51 10.9 1.7 1.6 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein COX16 ALMT PF11744.8 KXS22288.1 - 0.21 10.4 2.1 0.32 9.8 2.1 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter Connexin PF00029.19 KXS22288.1 - 0.21 11.3 3.0 0.33 10.7 3.0 1.2 1 0 0 1 1 1 0 Connexin FAM176 PF14851.6 KXS22288.1 - 2.2 8.0 5.7 1.2 8.8 3.2 1.7 2 0 0 2 2 2 0 FAM176 family VWA_2 PF13519.6 KXS22289.1 - 0.00092 19.8 0.1 0.0028 18.3 0.1 1.9 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 KXS22289.1 - 0.011 16.1 0.0 0.027 14.7 0.0 1.7 1 0 0 1 1 1 0 von Willebrand factor type A domain tRNA-synt_2b PF00587.25 KXS22290.1 - 3.9e-33 114.9 0.0 5.5e-33 114.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KXS22290.1 - 4.9e-10 39.4 0.1 1.4e-09 38.0 0.1 1.7 1 0 0 1 1 1 1 Anticodon binding domain Arf PF00025.21 KXS22291.1 - 7e-08 32.1 0.0 1.2e-07 31.4 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family HIG_1_N PF04588.13 KXS22292.1 - 4.6e-06 26.7 0.4 1e-05 25.6 0.4 1.6 1 0 0 1 1 1 1 Hypoxia induced protein conserved region Pyr_redox_2 PF07992.14 KXS22293.1 - 1e-06 28.2 0.0 8.8e-06 25.2 0.0 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXS22293.1 - 0.0026 17.7 0.0 0.015 15.3 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KXS22293.1 - 0.0088 16.3 0.0 0.019 15.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Atg8 PF02991.16 KXS22294.1 - 1.8e-49 166.2 0.3 2.2e-49 166.0 0.3 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 KXS22294.1 - 2.3e-06 27.9 0.1 3e-06 27.5 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 CCDC50_N PF15295.6 KXS22295.1 - 0.0035 17.5 4.0 0.0035 17.5 4.0 2.2 2 0 0 2 2 2 1 Coiled-coil domain-containing protein 50 N-terminus Spt20 PF12090.8 KXS22295.1 - 0.0055 16.4 7.7 0.0093 15.6 7.7 1.3 1 0 0 1 1 1 1 Spt20 family SARAF PF06682.12 KXS22295.1 - 0.098 12.3 7.2 0.2 11.3 7.2 1.5 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Ndc1_Nup PF09531.10 KXS22295.1 - 7.5 5.1 14.7 11 4.6 14.7 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup VPS9 PF02204.18 KXS22296.1 - 1.5e-21 76.5 0.0 2.4e-21 75.9 0.0 1.3 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 KXS22296.1 - 0.0007 19.9 0.0 0.0016 18.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5601) Dimer_Tnp_hAT PF05699.14 KXS22297.1 - 1.3e-11 44.2 0.0 1.3e-11 44.1 0.0 1.0 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region FGGY_N PF00370.21 KXS22298.1 - 0.17 11.4 0.0 0.17 11.4 0.0 1.0 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain Sterol_MT_C PF08498.10 KXS22299.1 - 6e-25 87.4 0.3 1e-24 86.6 0.3 1.4 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal CMAS PF02353.20 KXS22299.1 - 1.2e-11 44.5 0.0 1.6e-11 44.0 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.12 KXS22299.1 - 1.9e-11 44.5 0.0 6e-11 42.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXS22299.1 - 4.3e-10 40.2 0.0 8.5e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXS22299.1 - 2.1e-09 37.3 0.0 3e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXS22299.1 - 6.5e-09 35.8 0.0 1.3e-08 34.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain FCD PF07729.12 KXS22299.1 - 0.00014 22.3 0.0 0.00028 21.3 0.0 1.5 1 0 0 1 1 1 1 FCD domain Methyltransf_12 PF08242.12 KXS22299.1 - 0.0018 19.0 0.0 0.0048 17.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 KXS22299.1 - 0.017 14.7 0.0 0.03 13.9 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW PCMT PF01135.19 KXS22299.1 - 0.025 14.3 0.1 0.048 13.4 0.1 1.5 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Tap-RNA_bind PF09162.10 KXS22299.1 - 0.032 14.1 0.0 0.059 13.2 0.0 1.4 1 0 0 1 1 1 0 Tap, RNA-binding Pox_MCEL PF03291.16 KXS22299.1 - 0.045 12.9 0.0 0.11 11.5 0.0 1.6 2 0 0 2 2 2 0 mRNA capping enzyme Methyltransf_15 PF09445.10 KXS22299.1 - 0.045 13.3 0.1 0.072 12.7 0.1 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_28 PF02636.17 KXS22301.1 - 3e-34 118.9 0.0 3.8e-34 118.5 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_12 PF08242.12 KXS22301.1 - 0.01 16.6 0.0 0.025 15.3 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain cNMP_binding PF00027.29 KXS22302.1 - 5.9e-18 64.7 0.0 1e-17 63.9 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans PF00520.31 KXS22302.1 - 5.7e-05 22.5 12.0 8.4e-05 21.9 12.0 1.3 1 0 0 1 1 1 1 Ion transport protein DUF3381 PF11861.8 KXS22302.1 - 0.0093 15.8 7.1 0.0093 15.8 7.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3381) HHH_4 PF14490.6 KXS22302.1 - 0.092 12.7 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix containing domain MCU PF04678.13 KXS22303.1 - 0.17 12.0 4.7 0.29 11.2 4.7 1.3 1 0 0 1 1 1 0 Mitochondrial calcium uniporter Plasmodium_Vir PF05795.11 KXS22303.1 - 0.29 10.5 7.2 0.66 9.3 7.2 1.6 1 0 0 1 1 1 0 Plasmodium vivax Vir protein MAT1 PF06391.13 KXS22303.1 - 0.59 9.9 17.9 1.2 8.9 17.9 1.4 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 RR_TM4-6 PF06459.12 KXS22303.1 - 0.78 9.5 10.5 1.7 8.4 10.5 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CLN3 PF02487.17 KXS22303.1 - 1.3 8.0 2.5 2 7.4 2.5 1.2 1 0 0 1 1 1 0 CLN3 protein V_ATPase_I PF01496.19 KXS22303.1 - 1.7 6.5 7.2 2.4 6.0 7.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2828 PF11443.8 KXS22303.1 - 2.7 6.0 11.0 4.4 5.3 11.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DUF4407 PF14362.6 KXS22303.1 - 7 5.9 10.5 11 5.3 10.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) UcrQ PF02939.16 KXS22304.1 - 1.8e-20 72.7 0.3 2.2e-20 72.3 0.3 1.1 1 0 0 1 1 1 1 UcrQ family Cyt_b-c1_8 PF10890.8 KXS22304.1 - 0.017 15.5 0.0 0.032 14.6 0.0 1.4 1 1 0 1 1 1 0 Cytochrome b-c1 complex subunit 8 AIRS_C PF02769.22 KXS22305.1 - 6.1e-23 81.7 0.0 9.7e-23 81.0 0.0 1.3 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.24 KXS22305.1 - 2e-07 31.5 0.1 6.2e-07 30.0 0.0 1.8 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain Usp PF00582.26 KXS22306.1 - 0.00015 22.3 0.0 0.0002 21.9 0.0 1.2 1 0 0 1 1 1 1 Universal stress protein family Got1 PF04178.12 KXS22307.1 - 2.3e-16 60.2 14.2 2.9e-16 59.9 14.2 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family DUF308 PF03729.13 KXS22307.1 - 0.021 15.1 11.7 0.021 15.1 11.7 1.7 1 1 1 2 2 2 0 Short repeat of unknown function (DUF308) CPP1-like PF11833.8 KXS22307.1 - 0.61 9.7 2.6 0.76 9.4 2.6 1.1 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like DUF1129 PF06570.11 KXS22307.1 - 2.5 7.5 7.1 3.1 7.2 7.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) Profilin PF00235.19 KXS22308.1 - 2.1e-23 83.0 0.1 2.3e-23 82.8 0.1 1.0 1 0 0 1 1 1 1 Profilin DUF2997 PF11211.8 KXS22308.1 - 0.027 14.3 0.0 0.1 12.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2997) T6SS_Vgr PF13296.6 KXS22308.1 - 0.053 13.7 0.0 0.092 12.9 0.0 1.6 1 0 0 1 1 1 0 Putative type VI secretion system Rhs element Vgr Tox-REase-2 PF15646.6 KXS22308.1 - 0.09 13.0 0.0 0.17 12.1 0.0 1.4 1 1 0 1 1 1 0 Restriction endonuclease fold toxin 2 RNase_PH PF01138.21 KXS22309.1 - 1.4e-27 96.8 0.0 1.6e-27 96.6 0.0 1.0 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Band_7 PF01145.25 KXS22310.1 - 3e-23 82.7 3.7 4.7e-23 82.1 2.9 1.7 1 1 1 2 2 2 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 KXS22310.1 - 0.00053 19.2 1.9 0.00067 18.8 1.9 1.1 1 0 0 1 1 1 1 SigmaW regulon antibacterial Peptidase_S66 PF02016.15 KXS22310.1 - 0.025 14.7 0.3 0.062 13.4 0.3 1.6 1 1 1 2 2 2 0 LD-carboxypeptidase N-terminal domain MDM31_MDM32 PF08118.11 KXS22311.1 - 5.6e-122 408.1 0.0 5e-121 404.9 0.0 1.9 1 1 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins Phage_head_fibr PF11133.8 KXS22311.1 - 0.1 12.0 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Head fiber protein BET PF17035.5 KXS22312.1 - 1.1e-15 57.5 2.8 2.2e-15 56.6 2.8 1.5 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation GATA PF00320.27 KXS22312.1 - 1.4e-11 43.8 5.7 2.4e-11 43.0 5.7 1.4 1 0 0 1 1 1 1 GATA zinc finger DZR PF12773.7 KXS22312.1 - 0.13 12.3 0.5 0.24 11.4 0.5 1.4 1 0 0 1 1 1 0 Double zinc ribbon PIG-U PF06728.13 KXS22313.1 - 4.4e-101 338.7 23.9 5.2e-101 338.5 23.9 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U DUF3464 PF11947.8 KXS22313.1 - 0.26 11.0 0.4 0.52 10.0 0.4 1.5 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Phenol_monoox PF04663.12 KXS22313.1 - 0.3 11.3 1.4 2.8 8.2 0.2 2.5 2 0 0 2 2 2 0 Phenol hydroxylase conserved region Sec62 PF03839.16 KXS22313.1 - 3.9 6.9 6.7 0.18 11.3 0.2 2.0 2 0 0 2 2 2 0 Translocation protein Sec62 HTH_11 PF08279.12 KXS22314.1 - 0.00031 20.6 0.0 0.00058 19.8 0.0 1.4 1 0 0 1 1 1 1 HTH domain HTH_32 PF13565.6 KXS22314.1 - 0.00077 20.0 0.4 0.16 12.6 0.2 2.1 2 0 0 2 2 2 1 Homeodomain-like domain HTH_7 PF02796.15 KXS22314.1 - 0.0011 19.0 0.0 0.02 15.0 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_23 PF13384.6 KXS22314.1 - 0.0015 18.3 0.0 0.0026 17.5 0.0 1.3 1 0 0 1 1 1 1 Homeodomain-like domain HTH_17 PF12728.7 KXS22314.1 - 0.0081 16.3 0.0 0.014 15.6 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_28 PF13518.6 KXS22314.1 - 0.013 15.6 0.1 0.023 14.8 0.1 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Tnp_1_2 PF13022.6 KXS22314.1 - 0.023 14.8 0.0 0.037 14.2 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase HTH_3 PF01381.22 KXS22314.1 - 0.023 14.8 0.0 0.038 14.1 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix HTH_Tnp_IS630 PF01710.16 KXS22314.1 - 0.03 14.3 0.0 0.041 13.9 0.0 1.3 1 0 0 1 1 1 0 Transposase HTH_29 PF13551.6 KXS22314.1 - 0.14 12.2 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn helix HTH_DeoR PF08220.12 KXS22314.1 - 0.19 11.5 0.0 0.3 10.9 0.0 1.3 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain HTH_26 PF13443.6 KXS22314.1 - 0.2 12.1 0.0 0.33 11.4 0.0 1.3 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain Aminotran_1_2 PF00155.21 KXS22315.1 - 1.1e-81 274.8 0.0 1.6e-81 274.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KXS22315.1 - 1e-05 24.3 0.0 1.5e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 KXS22315.1 - 2.1e-05 24.0 0.1 4e-05 23.1 0.1 1.5 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 KXS22315.1 - 4.1e-05 22.7 0.0 6.6e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Preseq_ALAS PF09029.10 KXS22315.1 - 0.61 10.6 4.8 3.8 8.0 1.0 3.1 1 1 1 2 2 2 0 5-aminolevulinate synthase presequence SNARE_assoc PF09335.11 KXS22316.1 - 3.4e-05 24.3 0.4 3.4e-05 24.3 0.4 1.8 2 0 0 2 2 2 1 SNARE associated Golgi protein DUF4703 PF15775.5 KXS22316.1 - 0.033 14.0 1.1 0.064 13.1 1.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4703) AF-4 PF05110.13 KXS22316.1 - 7.4 4.5 8.4 9.6 4.1 8.4 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Ribosomal_S30 PF04758.14 KXS22317.1 - 5.6e-30 103.3 8.8 6.2e-30 103.2 8.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 LRR_6 PF13516.6 KXS22320.1 - 1.7 8.9 13.8 52 4.3 0.2 6.0 7 0 0 7 7 7 0 Leucine Rich repeat SBP_bac_11 PF13531.6 KXS22321.1 - 1.5e-16 60.9 0.1 1.5e-16 60.9 0.1 2.2 2 1 0 3 3 3 1 Bacterial extracellular solute-binding protein VWA PF00092.28 KXS22321.1 - 1.1e-10 42.0 0.5 3.2e-10 40.5 0.5 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KXS22321.1 - 1.7e-09 38.3 1.9 4.4e-09 36.9 0.4 2.2 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_3 PF13768.6 KXS22321.1 - 2.5e-09 37.3 0.0 6.2e-09 36.0 0.0 1.7 1 1 0 1 1 1 1 von Willebrand factor type A domain SBP_bac_8 PF13416.6 KXS22321.1 - 0.0022 17.8 0.6 0.0046 16.8 0.6 1.5 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein VWA_CoxE PF05762.14 KXS22321.1 - 0.0027 17.1 0.3 0.0059 16.0 0.3 1.5 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein CobT_C PF11775.8 KXS22321.1 - 0.094 12.3 0.1 0.18 11.4 0.1 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT VWA domain Methyltransf_25 PF13649.6 KXS22323.1 - 6.8e-06 26.7 0.0 8e-05 23.3 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXS22323.1 - 7.6e-06 25.8 0.0 1.1e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXS22323.1 - 9.3e-06 26.3 0.0 4.4e-05 24.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXS22323.1 - 7.1e-05 22.7 0.1 0.00029 20.6 0.1 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXS22323.1 - 0.00025 21.7 0.0 0.00083 20.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KXS22323.1 - 0.069 12.5 0.0 0.088 12.2 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MetW PF07021.12 KXS22323.1 - 0.12 11.9 0.1 0.21 11.1 0.1 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW AAA_12 PF13087.6 KXS22325.1 - 4.4e-54 183.1 0.0 6.5e-54 182.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KXS22325.1 - 1.9e-53 181.9 0.0 5.9e-53 180.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KXS22325.1 - 1.4e-12 47.7 0.6 1.1e-10 41.6 0.6 2.6 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 KXS22325.1 - 1.5e-09 37.9 0.1 0.0099 15.6 0.0 3.3 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 KXS22325.1 - 6.1e-08 33.1 0.0 2.7e-07 31.0 0.0 2.1 2 1 0 2 2 2 1 AAA domain ResIII PF04851.15 KXS22325.1 - 6.5e-05 23.0 0.0 0.00038 20.5 0.0 2.2 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_16 PF13191.6 KXS22325.1 - 8e-05 23.1 0.3 0.00018 22.0 0.3 1.6 1 0 0 1 1 1 1 AAA ATPase domain UvrD_C_2 PF13538.6 KXS22325.1 - 0.00013 21.8 0.4 0.0045 16.8 0.1 2.5 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_22 PF13401.6 KXS22325.1 - 0.0019 18.5 0.2 0.014 15.7 0.0 2.6 4 0 0 4 4 1 1 AAA domain AAA PF00004.29 KXS22325.1 - 0.0024 18.3 0.5 0.028 14.8 0.1 2.7 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 KXS22325.1 - 0.0026 17.4 0.3 0.0085 15.7 0.1 1.9 2 0 0 2 2 2 1 AAA domain PIF1 PF05970.14 KXS22325.1 - 0.0041 16.3 0.0 0.54 9.4 0.0 2.4 2 1 0 2 2 2 1 PIF1-like helicase DUF2075 PF09848.9 KXS22325.1 - 0.0045 16.3 4.8 0.16 11.1 0.1 2.6 3 0 0 3 3 3 2 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.14 KXS22325.1 - 0.0061 16.4 0.1 0.22 11.4 0.0 2.6 3 0 0 3 3 3 1 Helicase AAA_24 PF13479.6 KXS22325.1 - 0.017 14.8 0.1 0.34 10.6 0.1 2.5 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.22 KXS22325.1 - 0.018 14.6 0.6 0.52 9.9 0.0 2.8 4 0 0 4 4 4 0 SRP54-type protein, GTPase domain UvrD-helicase PF00580.21 KXS22325.1 - 0.031 13.8 0.0 0.2 11.1 0.0 2.1 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain PhoH PF02562.16 KXS22325.1 - 0.049 13.1 0.0 3.4 7.0 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein NTPase_1 PF03266.15 KXS22325.1 - 0.15 11.9 1.2 3.6 7.5 0.1 2.4 2 0 0 2 2 2 0 NTPase F-box-like PF12937.7 KXS22326.1 - 2.6e-07 30.4 0.4 7.2e-07 29.0 0.4 1.8 1 0 0 1 1 1 1 F-box-like NODP PF07684.12 KXS22326.1 - 0.18 12.0 0.1 0.43 10.8 0.1 1.6 1 0 0 1 1 1 0 NOTCH protein LRR_8 PF13855.6 KXS22327.1 - 4.2e-05 23.2 0.0 0.0034 17.1 0.1 2.3 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KXS22327.1 - 0.0096 16.3 0.1 7.5 7.1 0.0 3.0 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) Phage_holin_3_6 PF07332.11 KXS22327.1 - 0.045 13.8 0.2 0.079 13.0 0.2 1.3 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Herpes_gE PF02480.16 KXS22327.1 - 0.095 11.4 0.1 0.15 10.8 0.1 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E GFO_IDH_MocA PF01408.22 KXS22328.1 - 2.6e-16 60.5 0.0 4.8e-16 59.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold BCA_ABC_TP_C PF12399.8 KXS22328.1 - 0.011 15.7 0.3 0.025 14.5 0.3 1.7 1 0 0 1 1 1 0 Branched-chain amino acid ATP-binding cassette transporter LAT PF15234.6 KXS22328.1 - 0.12 12.1 0.2 0.2 11.4 0.2 1.2 1 0 0 1 1 1 0 Linker for activation of T-cells AbiEi_4 PF13338.6 KXS22331.1 - 0.02 15.0 0.3 0.2 11.9 0.2 2.3 2 0 0 2 2 2 0 Transcriptional regulator, AbiEi antitoxin HEAT_2 PF13646.6 KXS22333.1 - 4.8e-07 30.1 3.6 0.051 14.0 0.1 6.9 7 1 1 8 8 8 2 HEAT repeats HEAT PF02985.22 KXS22333.1 - 3.6e-06 26.8 6.0 13 6.4 0.0 8.7 8 0 0 8 8 8 1 HEAT repeat Cnd3 PF12719.7 KXS22333.1 - 4.1e-05 22.9 0.1 0.0063 15.7 0.0 3.0 2 1 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT_EZ PF13513.6 KXS22333.1 - 0.00087 19.7 6.2 6.2 7.4 0.0 7.1 5 1 2 7 7 7 1 HEAT-like repeat IFRD PF05004.13 KXS22333.1 - 0.0063 15.7 1.0 15 4.6 0.0 4.8 5 1 1 6 6 6 1 Interferon-related developmental regulator (IFRD) Arm PF00514.23 KXS22333.1 - 0.0082 16.2 1.2 0.19 11.9 0.0 3.5 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat ATP_bind_3 PF01171.20 KXS22334.1 - 7.9e-18 64.9 0.0 1.1e-17 64.4 0.0 1.2 1 0 0 1 1 1 1 PP-loop family zn-ribbon_14 PF16503.5 KXS22334.1 - 7e-15 54.2 3.8 7e-15 54.2 3.8 3.5 4 0 0 4 4 4 1 Zinc-ribbon DUF4428 PF14471.6 KXS22334.1 - 0.0086 16.0 3.1 0.029 14.3 0.5 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4428) PAPS_reduct PF01507.19 KXS22334.1 - 0.023 14.8 0.0 0.03 14.4 0.0 1.2 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family TF_Zn_Ribbon PF08271.12 KXS22334.1 - 0.047 13.2 0.8 0.047 13.2 0.8 3.4 3 1 0 3 3 3 0 TFIIB zinc-binding tRNA_Me_trans PF03054.16 KXS22334.1 - 0.061 12.1 0.0 0.11 11.3 0.0 1.4 1 1 0 1 1 1 0 tRNA methyl transferase OrfB_Zn_ribbon PF07282.11 KXS22334.1 - 0.39 10.7 8.4 0.27 11.2 0.6 3.0 3 0 0 3 3 3 0 Putative transposase DNA-binding domain DZR PF12773.7 KXS22334.1 - 1.4 9.0 8.6 9.3 6.4 0.2 3.3 3 0 0 3 3 3 0 Double zinc ribbon NMD3 PF04981.13 KXS22334.1 - 1.5 8.2 4.1 7 6.0 0.3 2.3 2 0 0 2 2 2 0 NMD3 family MFS_2 PF13347.6 KXS22336.1 - 6.1e-07 28.4 5.3 6.8e-07 28.2 5.3 1.2 1 0 0 1 1 1 1 MFS/sugar transport protein MFS_1 PF07690.16 KXS22336.1 - 3e-05 23.1 9.3 3.9e-05 22.7 9.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF3464 PF11947.8 KXS22336.1 - 0.074 12.8 3.5 0.15 11.8 3.5 1.7 1 1 0 1 1 1 0 Photosynthesis affected mutant 68 DUF4229 PF14012.6 KXS22336.1 - 1.5 9.0 7.7 0.31 11.2 1.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF4229) C2 PF00168.30 KXS22338.1 - 5.9e-05 23.3 0.0 0.23 11.8 0.0 2.8 2 0 0 2 2 2 2 C2 domain DUF3522 PF12036.8 KXS22339.1 - 0.059 13.7 2.5 0.16 12.2 2.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3522) SAYSvFN PF10260.9 KXS22339.1 - 0.45 10.5 0.1 0.45 10.5 0.1 2.2 2 1 1 3 3 3 0 Uncharacterized conserved domain (SAYSvFN) Rhomboid PF01694.22 KXS22340.1 - 2.4e-12 47.1 11.1 6.8e-12 45.6 11.1 1.7 1 1 0 1 1 1 1 Rhomboid family HECT PF00632.25 KXS22341.1 - 2.8e-96 322.6 0.0 3.3e-96 322.4 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Statherin PF03875.13 KXS22341.1 - 0.0042 17.1 0.1 0.013 15.6 0.1 1.8 1 0 0 1 1 1 1 Statherin IQ PF00612.27 KXS22342.1 - 0.13 12.1 0.8 0.4 10.6 0.8 1.8 1 0 0 1 1 1 0 IQ calmodulin-binding motif Aldo_ket_red PF00248.21 KXS22343.1 - 1.3e-56 192.0 0.0 1.5e-56 191.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Glyco_hydro_26 PF02156.15 KXS22344.1 - 9e-11 41.8 0.7 1.3e-10 41.2 0.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 26 DUF4874 PF16173.5 KXS22344.1 - 0.015 15.0 0.0 0.02 14.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4874) Pkinase PF00069.25 KXS22345.1 - 8.6e-75 251.5 0.0 1.2e-74 251.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS22345.1 - 9.3e-40 136.5 0.0 1.3e-39 136.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXS22345.1 - 7e-05 22.3 0.0 0.0015 17.9 0.0 2.3 2 1 0 2 2 2 1 Kinase-like APH PF01636.23 KXS22345.1 - 0.002 18.1 0.0 1.4 8.8 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KXS22345.1 - 0.024 14.0 0.2 0.051 12.9 0.2 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 KXS22345.1 - 0.051 13.1 0.0 0.16 11.5 0.0 1.7 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL FTA2 PF13095.6 KXS22345.1 - 0.098 12.3 0.1 0.18 11.4 0.1 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 CAF20 PF17052.5 KXS22345.1 - 0.13 12.4 0.1 0.29 11.3 0.1 1.5 1 0 0 1 1 1 0 Cap associated factor Ribosomal_S21e PF01249.18 KXS22347.1 - 1.7e-41 140.2 0.0 1.9e-41 140.0 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e CLN3 PF02487.17 KXS22348.1 - 0.0081 15.2 1.2 0.016 14.3 1.2 1.4 1 0 0 1 1 1 1 CLN3 protein Peptidase_S49_N PF08496.10 KXS22348.1 - 0.44 10.6 6.7 0.99 9.5 6.7 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Pex26 PF07163.12 KXS22348.1 - 5.4 6.2 8.2 9.3 5.5 8.2 1.3 1 0 0 1 1 1 0 Pex26 protein Neur_chan_memb PF02932.16 KXS22348.1 - 5.5 7.0 10.2 2.1 8.3 1.2 2.4 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region YfhO PF09586.10 KXS22348.1 - 6.6 4.8 7.5 9.4 4.3 7.5 1.2 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Thiolase_N PF00108.23 KXS22349.1 - 2.2e-96 322.2 1.7 2.2e-96 322.2 1.7 1.6 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KXS22349.1 - 8.9e-46 154.5 1.6 3.1e-45 152.8 1.6 2.0 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KXS22349.1 - 4.5e-05 23.2 1.9 0.00017 21.2 0.4 2.7 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain IBR PF01485.21 KXS22350.1 - 0.0012 19.0 0.6 0.0022 18.2 0.6 1.3 1 0 0 1 1 1 1 IBR domain, a half RING-finger domain zf-C3HC4_3 PF13920.6 KXS22350.1 - 0.0029 17.4 4.3 0.0029 17.4 4.3 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXS22350.1 - 0.0084 15.9 5.1 0.0084 15.9 5.1 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXS22350.1 - 0.02 14.9 4.9 0.049 13.7 4.9 1.8 1 1 0 1 1 1 0 RING-type zinc-finger zf-C3HC4 PF00097.25 KXS22350.1 - 0.025 14.5 5.9 0.057 13.3 6.0 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Phe_tRNA-synt_N PF02912.18 KXS22350.1 - 0.11 12.4 0.3 0.46 10.5 0.0 2.2 2 1 0 2 2 2 0 Aminoacyl tRNA synthetase class II, N-terminal domain zf-RING_2 PF13639.6 KXS22350.1 - 0.24 11.7 9.6 0.069 13.5 6.0 1.8 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4_4 PF15227.6 KXS22350.1 - 0.99 9.6 10.1 0.19 11.9 6.0 1.9 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 KXS22350.1 - 1.5 8.8 9.7 3.2 7.8 9.7 1.6 1 1 0 1 1 1 0 zinc-RING finger domain ASXH PF13919.6 KXS22351.1 - 0.022 14.8 2.1 0.044 13.8 2.1 1.5 1 0 0 1 1 1 0 Asx homology domain Borrelia_P83 PF05262.11 KXS22351.1 - 0.91 7.9 15.1 1.1 7.6 15.1 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein B12D PF06522.11 KXS22352.1 - 0.0014 18.4 0.0 0.61 9.9 0.0 2.3 2 0 0 2 2 2 2 NADH-ubiquinone reductase complex 1 MLRQ subunit Pab87_oct PF13969.6 KXS22352.1 - 0.018 15.1 0.0 3.2 7.9 0.0 2.2 2 0 0 2 2 2 0 Pab87 octamerisation domain DUF4313 PF14190.6 KXS22352.1 - 0.068 13.2 0.0 12 5.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4313) DUF5353 PF17304.2 KXS22352.1 - 0.069 12.9 0.0 11 5.9 0.0 2.7 3 0 0 3 3 3 0 Family of unknown function (DUF5353) DnaB_2 PF07261.11 KXS22352.1 - 0.074 12.8 0.8 20 5.0 0.0 3.0 3 0 0 3 3 3 0 Replication initiation and membrane attachment FAM165 PF14981.6 KXS22352.1 - 0.11 12.3 0.0 20 5.0 0.0 2.3 2 0 0 2 2 2 0 FAM165 family Ribosomal_L31 PF01197.18 KXS22352.1 - 0.34 11.2 1.0 35 4.7 0.1 2.5 2 0 0 2 2 2 0 Ribosomal protein L31 DPCD PF14913.6 KXS22353.1 - 1.2e-45 155.3 0.0 1.5e-45 154.9 0.0 1.1 1 0 0 1 1 1 1 DPCD protein family Pkinase PF00069.25 KXS22354.1 - 5.1e-70 235.9 0.0 6.4e-70 235.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS22354.1 - 1e-34 120.0 0.0 2.8e-34 118.6 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase DUF2397 PF09660.10 KXS22355.1 - 0.11 11.4 0.6 0.14 11.1 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2397) ATP_transf PF09830.9 KXS22356.1 - 1.6e-20 73.0 0.0 3.4e-20 72.0 0.0 1.6 1 0 0 1 1 1 1 ATP adenylyltransferase CwfJ_C_1 PF04677.15 KXS22356.1 - 0.0045 16.9 0.0 0.0084 16.0 0.0 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 DUF4922 PF16269.5 KXS22356.1 - 0.06 13.1 0.0 0.22 11.3 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4922) GalP_UDP_transf PF01087.22 KXS22356.1 - 0.2 12.1 0.0 0.33 11.4 0.0 1.3 1 0 0 1 1 1 0 Galactose-1-phosphate uridyl transferase, N-terminal domain Pkinase PF00069.25 KXS22357.1 - 2.5e-77 259.8 0.0 3e-77 259.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS22357.1 - 1.8e-42 145.4 0.0 2.5e-42 145.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXS22357.1 - 6.8e-11 42.0 0.0 4.1e-07 29.6 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 KXS22357.1 - 3e-07 30.0 0.1 4.8e-07 29.3 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXS22357.1 - 2.3e-06 27.7 0.0 0.00026 21.0 0.0 2.5 2 1 1 3 3 3 2 Phosphotransferase enzyme family RIO1 PF01163.22 KXS22357.1 - 5.9e-06 26.0 0.3 1e-05 25.2 0.3 1.3 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 KXS22357.1 - 0.00019 20.5 0.3 0.00026 20.0 0.3 1.1 1 0 0 1 1 1 1 Haspin like kinase domain YukC PF10140.9 KXS22357.1 - 0.00048 19.1 0.1 0.00065 18.6 0.1 1.1 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC Seadorna_VP7 PF07387.11 KXS22357.1 - 0.0098 15.0 0.0 0.014 14.4 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 FTA2 PF13095.6 KXS22357.1 - 0.035 13.7 0.1 0.098 12.3 0.1 1.7 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 HELP PF03451.14 KXS22358.1 - 8.5e-08 31.9 0.0 1.9e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 HELP motif WD40 PF00400.32 KXS22358.1 - 0.015 16.1 4.1 3.6 8.6 0.0 3.8 3 1 0 3 3 3 0 WD domain, G-beta repeat MORN PF02493.20 KXS22359.1 - 1.4e-31 106.4 33.8 5.9e-06 25.9 1.0 7.5 7 0 0 7 7 7 7 MORN repeat WES_acyltransf PF03007.16 KXS22360.1 - 2e-10 40.9 0.0 5.7e-10 39.4 0.0 1.7 2 0 0 2 2 2 1 Wax ester synthase-like Acyl-CoA acyltransferase domain ArgJ PF01960.18 KXS22361.1 - 1.4e-146 488.0 1.5 1.8e-146 487.7 1.5 1.1 1 0 0 1 1 1 1 ArgJ family Sel1 PF08238.12 KXS22362.1 - 1.7e-33 114.3 21.2 3.8e-07 30.6 0.3 7.3 7 0 0 7 7 7 7 Sel1 repeat Amidohydro_3 PF07969.11 KXS22363.1 - 3.4e-59 201.6 0.0 4e-59 201.3 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 KXS22363.1 - 3.7e-15 56.1 0.2 7.1e-10 38.7 0.0 3.9 4 0 0 4 4 4 3 Amidohydrolase family PA14 PF07691.12 KXS22363.1 - 0.085 12.7 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 PA14 domain MCU PF04678.13 KXS22364.1 - 2.6e-21 76.5 0.1 2.8e-21 76.4 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial calcium uniporter Phage_holin_3_6 PF07332.11 KXS22364.1 - 0.031 14.3 0.0 0.046 13.7 0.0 1.2 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DUF1097 PF06496.11 KXS22364.1 - 0.034 14.3 3.8 0.073 13.2 3.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1097) FERM_M PF00373.18 KXS22365.1 - 2.1e-23 83.0 0.0 3.8e-23 82.1 0.0 1.4 1 0 0 1 1 1 1 FERM central domain Guanylate_cyc PF00211.20 KXS22366.1 - 3.8e-18 65.8 0.0 1.6e-11 44.2 0.0 2.2 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain Pyr_redox_2 PF07992.14 KXS22367.1 - 1e-51 175.9 4.3 1.6e-51 175.3 4.3 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.26 KXS22367.1 - 7.9e-19 67.4 0.1 2.2e-18 65.9 0.1 1.8 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain Pyr_redox PF00070.27 KXS22367.1 - 2.8e-15 56.6 4.7 6.3e-10 39.5 0.4 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.6 KXS22367.1 - 2.1e-07 30.8 0.0 6.2e-07 29.3 0.0 1.8 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Pyr_redox_3 PF13738.6 KXS22367.1 - 8.9e-05 21.9 1.5 0.2 10.9 0.0 3.0 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXS22367.1 - 0.00012 20.9 0.5 0.4 9.3 0.0 2.5 2 0 0 2 2 2 2 HI0933-like protein Reductase_C PF14759.6 KXS22367.1 - 0.00012 22.5 0.0 0.00035 21.1 0.0 1.8 1 0 0 1 1 1 1 Reductase C-terminal DAO PF01266.24 KXS22367.1 - 0.0083 15.7 6.6 0.12 11.9 0.1 2.9 2 1 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KXS22367.1 - 0.016 14.5 1.2 0.41 9.8 0.1 2.5 2 0 0 2 2 2 0 FAD binding domain NAD_binding_8 PF13450.6 KXS22367.1 - 0.036 14.3 2.1 0.43 10.8 0.3 2.6 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KXS22367.1 - 0.049 12.9 0.7 4.2 6.5 0.1 3.0 3 0 0 3 3 3 0 Thi4 family FAD_binding_2 PF00890.24 KXS22367.1 - 0.12 11.5 9.5 0.047 12.8 1.1 3.6 3 1 0 4 4 4 0 FAD binding domain NAD_binding_9 PF13454.6 KXS22367.1 - 1.2 9.1 3.5 10 6.1 0.1 2.9 3 0 0 3 3 3 0 FAD-NAD(P)-binding NTP_transferase PF00483.23 KXS22368.1 - 3.9e-27 95.4 0.0 5.6e-27 94.9 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 KXS22368.1 - 1.3e-10 40.6 10.0 1.7e-06 27.5 0.7 3.4 2 1 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 KXS22368.1 - 0.00062 20.2 0.0 0.0016 18.9 0.0 1.7 1 0 0 1 1 1 1 MobA-like NTP transferase domain Fucokinase PF07959.12 KXS22368.1 - 0.044 12.7 1.0 2.7 6.8 1.2 2.6 2 1 0 2 2 2 0 L-fucokinase DUF4954 PF16314.5 KXS22368.1 - 0.088 10.9 0.2 0.15 10.2 0.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4954) Hexapep_2 PF14602.6 KXS22368.1 - 0.093 12.5 0.0 0.093 12.5 0.0 3.2 3 0 0 3 3 3 0 Hexapeptide repeat of succinyl-transferase RAG1 PF12940.7 KXS22368.1 - 0.19 9.8 0.0 0.29 9.2 0.0 1.2 1 0 0 1 1 1 0 Recombination-activation protein 1 (RAG1), recombinase DNA_pol_lambd_f PF10391.9 KXS22369.1 - 0.0015 18.3 0.2 0.0043 16.9 0.2 1.8 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda Peptidase_S46 PF10459.9 KXS22369.1 - 1.6 7.3 13.1 2.7 6.5 13.1 1.4 1 0 0 1 1 1 0 Peptidase S46 DUF4407 PF14362.6 KXS22369.1 - 2.5 7.4 25.1 0.59 9.4 10.7 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Xan_ur_permease PF00860.20 KXS22370.1 - 6e-77 259.0 40.9 7.8e-77 258.6 40.9 1.1 1 0 0 1 1 1 1 Permease family RTX PF02382.15 KXS22370.1 - 0.021 14.5 1.8 0.034 13.8 1.8 1.2 1 0 0 1 1 1 0 N-terminal domain in RTX protein AIRS PF00586.24 KXS22370.1 - 0.41 11.3 5.4 5.5 7.7 0.8 2.9 2 0 0 2 2 2 0 AIR synthase related protein, N-terminal domain AAA PF00004.29 KXS22371.1 - 6.3e-44 149.6 0.0 1.5e-43 148.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KXS22371.1 - 6.2e-12 45.1 0.1 1.6e-11 43.8 0.1 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 KXS22371.1 - 9.3e-08 32.2 0.0 2.7e-07 30.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KXS22371.1 - 1e-07 32.2 0.0 2.1e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Prot_ATP_ID_OB PF16450.5 KXS22371.1 - 8.1e-07 28.9 0.7 1.9e-06 27.7 0.7 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_16 PF13191.6 KXS22371.1 - 2.1e-06 28.3 0.1 3.5e-05 24.3 0.1 2.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KXS22371.1 - 4.9e-05 23.6 1.3 0.0072 16.6 0.3 2.9 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.12 KXS22371.1 - 5.8e-05 22.9 0.0 0.00012 21.9 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 KXS22371.1 - 0.00082 18.7 0.0 0.0022 17.2 0.0 1.7 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 KXS22371.1 - 0.0013 18.9 0.0 0.0027 17.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KXS22371.1 - 0.0016 19.0 0.1 0.016 15.7 0.0 2.6 3 0 0 3 3 3 1 AAA domain IstB_IS21 PF01695.17 KXS22371.1 - 0.0026 17.5 0.0 0.0052 16.5 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_3 PF07726.11 KXS22371.1 - 0.0039 17.0 0.0 0.011 15.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF2072 PF09845.9 KXS22371.1 - 0.0047 17.2 0.5 0.01 16.1 0.5 1.5 1 0 0 1 1 1 1 Zn-ribbon containing protein PhoH PF02562.16 KXS22371.1 - 0.0068 15.9 0.0 0.12 11.8 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein DUF815 PF05673.13 KXS22371.1 - 0.0068 15.6 0.1 0.023 13.9 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Mg_chelatase PF01078.21 KXS22371.1 - 0.0082 15.5 0.0 0.017 14.5 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 KXS22371.1 - 0.0093 16.2 0.1 0.02 15.1 0.0 1.6 2 0 0 2 2 1 1 AAA domain TsaE PF02367.17 KXS22371.1 - 0.015 15.3 0.0 0.027 14.5 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase PF06745.13 KXS22371.1 - 0.015 14.6 0.0 0.04 13.3 0.0 1.7 1 0 0 1 1 1 0 KaiC APG6_N PF17675.1 KXS22371.1 - 0.017 15.7 2.0 0.035 14.6 2.0 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region Sigma54_activat PF00158.26 KXS22371.1 - 0.019 14.6 0.0 0.1 12.3 0.0 2.2 3 0 0 3 3 2 0 Sigma-54 interaction domain DASH_Dad2 PF08654.10 KXS22371.1 - 0.03 14.7 0.4 0.26 11.7 0.3 2.3 2 0 0 2 2 2 0 DASH complex subunit Dad2 AAA_7 PF12775.7 KXS22371.1 - 0.03 13.8 0.0 0.053 13.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_14 PF13173.6 KXS22371.1 - 0.032 14.3 0.0 0.066 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KXS22371.1 - 0.034 13.9 0.0 0.1 12.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KXS22371.1 - 0.038 14.4 0.0 0.069 13.5 0.0 1.5 1 0 0 1 1 1 0 RNA helicase RILP PF11461.8 KXS22371.1 - 0.046 13.9 2.3 0.11 12.7 2.3 1.6 1 0 0 1 1 1 0 Rab interacting lysosomal protein Zeta_toxin PF06414.12 KXS22371.1 - 0.055 12.7 0.2 0.21 10.8 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin Parvo_NS1 PF01057.17 KXS22371.1 - 0.059 12.5 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_25 PF13481.6 KXS22371.1 - 0.065 12.8 0.0 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 KXS22371.1 - 0.066 13.0 0.2 0.38 10.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 KXS22371.1 - 0.087 13.3 0.1 0.36 11.2 0.0 2.1 2 0 0 2 2 1 0 AAA domain SlyX PF04102.12 KXS22371.1 - 0.29 11.8 2.0 1.3 9.7 2.0 2.1 1 0 0 1 1 1 0 SlyX TolA_bind_tri PF16331.5 KXS22371.1 - 0.84 9.8 9.1 0.63 10.2 6.1 2.1 2 0 0 2 2 2 0 TolA binding protein trimerisation DUF810 PF05664.11 KXS22372.1 - 0.00024 19.8 0.5 0.00093 17.9 0.1 2.0 1 1 1 2 2 2 1 Plant family of unknown function (DUF810) Ribosomal_L30 PF00327.20 KXS22374.1 - 7e-10 38.7 0.1 1e-09 38.1 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e TSP_1 PF00090.19 KXS22376.1 - 1.3e-06 28.5 13.7 3.2e-06 27.3 13.7 1.7 1 1 0 1 1 1 1 Thrombospondin type 1 domain LRR_9 PF14580.6 KXS22377.1 - 1.7e-15 57.0 9.2 1.1e-14 54.3 9.2 2.4 1 1 1 2 2 2 1 Leucine-rich repeat LRR_4 PF12799.7 KXS22377.1 - 4.2e-14 52.4 36.0 9.6e-06 25.9 7.8 4.6 3 1 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXS22377.1 - 2.5e-08 33.6 21.3 3.5e-06 26.7 12.4 3.4 2 0 0 2 2 2 2 Leucine rich repeat Baculo_PEP_C PF04513.12 KXS22377.1 - 0.0038 17.3 3.6 0.0038 17.3 3.6 3.0 2 2 0 2 2 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus BAR PF03114.18 KXS22377.1 - 0.0043 16.7 1.0 0.0099 15.5 1.0 1.6 1 0 0 1 1 1 1 BAR domain MRFAP1 PF15155.6 KXS22377.1 - 0.013 16.0 1.0 0.03 14.9 0.2 2.1 2 0 0 2 2 2 0 MORF4 family-associated protein1 Gp-FAR-1 PF05823.12 KXS22377.1 - 0.049 14.0 1.0 0.17 12.3 1.0 2.0 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Apolipoprotein PF01442.18 KXS22377.1 - 0.051 13.5 1.8 0.19 11.6 1.4 2.1 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain Desmo_N PF06771.11 KXS22377.1 - 0.063 13.6 1.5 5.3 7.5 0.1 2.9 1 1 1 2 2 2 0 Viral Desmoplakin N-terminus Pex19 PF04614.12 KXS22377.1 - 0.093 12.5 1.2 0.19 11.5 1.2 1.4 1 0 0 1 1 1 0 Pex19 protein family DUF3972 PF13118.6 KXS22377.1 - 0.14 12.6 7.8 0.092 13.2 3.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3972) Cor1 PF04803.12 KXS22377.1 - 0.15 12.3 6.5 2.6 8.3 0.1 3.0 3 1 0 3 3 2 0 Cor1/Xlr/Xmr conserved region UPF0061 PF02696.14 KXS22377.1 - 0.2 10.4 1.9 0.36 9.6 1.9 1.4 1 0 0 1 1 1 0 Uncharacterized ACR, YdiU/UPF0061 family Cytochrom_B562 PF07361.11 KXS22377.1 - 0.39 11.4 2.6 1.4 9.7 1.0 2.6 2 0 0 2 2 2 0 Cytochrome b562 DUF810 PF05664.11 KXS22378.1 - 0.00016 20.4 1.3 0.00046 18.9 0.1 2.0 2 0 0 2 2 2 1 Plant family of unknown function (DUF810) MMtag PF10159.9 KXS22379.1 - 0.29 11.5 3.8 0.63 10.4 3.8 1.5 1 0 0 1 1 1 0 Multiple myeloma tumor-associated CDC27 PF09507.10 KXS22379.1 - 2.3 7.5 13.4 7.8 5.8 13.4 2.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Polysacc_deac_1 PF01522.21 KXS22380.1 - 3.1e-29 101.4 0.0 5.6e-29 100.5 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase Mucin PF01456.17 KXS22380.1 - 0.0088 16.0 30.7 0.0088 16.0 30.7 2.5 2 0 0 2 2 2 1 Mucin-like glycoprotein ETRAMP PF09716.10 KXS22380.1 - 0.42 10.7 4.7 0.86 9.7 4.7 1.4 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) RINGv PF12906.7 KXS22381.1 - 0.0025 17.9 1.2 0.0041 17.2 1.2 1.3 1 0 0 1 1 1 1 RING-variant domain EphA2_TM PF14575.6 KXS22382.1 - 0.00083 20.2 0.0 0.0016 19.2 0.0 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain PIRT PF15099.6 KXS22382.1 - 0.0027 17.3 0.2 0.0043 16.6 0.2 1.3 1 0 0 1 1 1 1 Phosphoinositide-interacting protein family RCR PF12273.8 KXS22382.1 - 0.011 16.4 0.0 0.018 15.7 0.0 1.3 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red TMEM154 PF15102.6 KXS22382.1 - 0.018 15.0 0.0 0.034 14.0 0.0 1.4 1 0 0 1 1 1 0 TMEM154 protein family EB PF01683.18 KXS22382.1 - 0.025 14.9 3.2 0.025 14.9 3.2 2.6 1 1 1 2 2 2 0 EB module Trp_oprn_chp PF09534.10 KXS22382.1 - 0.064 13.1 6.2 0.063 13.1 0.8 2.2 1 1 1 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) MFS_1 PF07690.16 KXS22383.1 - 9.1e-29 100.5 64.4 1.1e-21 77.2 27.4 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily LRR_6 PF13516.6 KXS22384.1 - 1.6e-16 58.9 18.8 0.0083 16.1 0.1 7.5 8 0 0 8 8 8 6 Leucine Rich repeat LRR_4 PF12799.7 KXS22384.1 - 0.00013 22.3 10.9 0.051 14.0 0.0 3.9 3 1 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KXS22384.1 - 0.0036 17.6 4.8 98 4.1 0.0 5.7 5 2 0 5 5 5 0 Leucine Rich Repeat AIRC PF00731.20 KXS22384.1 - 0.087 12.4 0.1 0.14 11.7 0.1 1.3 1 0 0 1 1 1 0 AIR carboxylase LRR_8 PF13855.6 KXS22384.1 - 1.3 8.8 14.0 6.5 6.6 1.9 4.1 3 2 1 4 4 4 0 Leucine rich repeat AAA PF00004.29 KXS22387.1 - 0.0063 16.9 0.0 0.0096 16.4 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 KXS22387.1 - 0.052 13.8 0.1 0.1 12.9 0.1 1.4 1 0 0 1 1 1 0 AAA domain NMO PF03060.15 KXS22388.1 - 8.2e-52 176.6 0.2 1.1e-51 176.2 0.2 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KXS22388.1 - 4.3e-08 32.5 0.0 1.6e-07 30.7 0.0 1.7 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KXS22388.1 - 1.6e-06 27.4 2.0 2.6e-06 26.7 2.0 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 KXS22388.1 - 0.1 11.7 1.1 0.2 10.7 0.7 1.6 2 0 0 2 2 2 0 Conserved region in glutamate synthase Transp_cyt_pur PF02133.15 KXS22389.1 - 5.5e-76 256.1 10.4 6.3e-76 255.9 10.4 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Alg6_Alg8 PF03155.15 KXS22389.1 - 0.018 14.1 1.6 0.026 13.5 1.6 1.2 1 0 0 1 1 1 0 ALG6, ALG8 glycosyltransferase family Asp_Glu_race PF01177.22 KXS22390.1 - 0.0012 18.7 0.0 0.0016 18.3 0.0 1.2 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase DUF3652 PF12372.8 KXS22390.1 - 0.085 12.8 0.0 0.41 10.6 0.0 2.2 2 0 0 2 2 2 0 Huntingtin protein region Nuc_sug_transp PF04142.15 KXS22391.1 - 8e-111 370.2 13.9 2.8e-110 368.4 13.9 1.7 1 1 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 KXS22391.1 - 3.8e-07 29.6 11.0 1.6e-06 27.6 11.0 1.9 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 KXS22391.1 - 8.6e-05 22.7 2.2 8.6e-05 22.7 2.2 2.9 3 1 0 3 3 3 1 EamA-like transporter family TPT PF03151.16 KXS22391.1 - 0.00075 18.9 0.5 0.00075 18.9 0.5 2.9 3 1 0 3 3 3 1 Triose-phosphate Transporter family PUNUT PF16913.5 KXS22391.1 - 0.92 8.7 19.4 0.081 12.1 13.2 2.1 2 1 0 2 2 2 0 Purine nucleobase transmembrane transport Picorna_P3A PF06363.11 KXS22391.1 - 4.1 7.3 5.2 4.2 7.3 0.0 3.1 3 1 1 4 4 4 0 Picornaviridae P3A protein DUF4407 PF14362.6 KXS22392.1 - 3.4 6.9 4.7 5.4 6.3 4.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Ion_trans_2 PF07885.16 KXS22394.1 - 1.5e-30 104.9 37.5 7e-17 61.2 10.7 3.1 3 1 1 4 4 4 2 Ion channel IRK PF01007.20 KXS22394.1 - 0.018 14.8 1.5 0.018 14.8 1.5 2.8 3 1 0 3 3 3 0 Inward rectifier potassium channel transmembrane domain Ion_trans PF00520.31 KXS22394.1 - 0.023 13.9 26.1 0.47 9.6 4.9 2.7 2 1 0 2 2 2 0 Ion transport protein CoA_binding_3 PF13727.6 KXS22394.1 - 0.088 12.8 0.1 0.088 12.8 0.1 3.3 3 1 1 4 4 4 0 CoA-binding domain DUF1633 PF07794.11 KXS22395.1 - 0.26 9.4 0.5 0.45 8.6 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1633) ATG16 PF08614.11 KXS22396.1 - 0.0003 21.1 1.9 0.00074 19.8 1.9 1.6 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Ank_3 PF13606.6 KXS22396.1 - 0.00031 21.0 0.0 0.0017 18.6 0.0 2.3 3 0 0 3 3 2 1 Ankyrin repeat ADIP PF11559.8 KXS22396.1 - 0.0042 17.2 5.5 0.0077 16.3 5.5 1.3 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding Ank PF00023.30 KXS22396.1 - 0.0073 16.7 0.0 0.18 12.3 0.0 2.8 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.7 KXS22396.1 - 0.021 15.4 0.0 0.058 14.0 0.0 1.7 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) DUF3584 PF12128.8 KXS22396.1 - 0.089 10.3 5.8 0.12 9.8 5.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Ank_5 PF13857.6 KXS22396.1 - 0.11 12.8 0.0 0.38 11.2 0.0 1.8 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Sec2p PF06428.11 KXS22396.1 - 0.39 10.7 3.8 0.71 9.9 3.8 1.3 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p Spc7 PF08317.11 KXS22396.1 - 0.58 9.0 4.1 0.91 8.3 4.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF3552 PF12072.8 KXS22396.1 - 1.7 8.0 9.9 12 5.2 10.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) ASD2 PF08687.11 KXS22396.1 - 9.6 5.7 10.0 16 4.9 10.0 1.3 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 Phi_1 PF04674.12 KXS22397.1 - 2.2e-22 79.7 2.9 7.2e-22 78.0 2.9 1.8 1 1 0 1 1 1 1 Phosphate-induced protein 1 conserved region LRR_8 PF13855.6 KXS22397.1 - 1.9e-06 27.5 9.4 0.00032 20.4 0.5 2.9 1 1 3 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 KXS22397.1 - 2.5e-06 27.7 11.9 0.042 14.3 0.5 3.7 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KXS22397.1 - 0.00059 20.0 7.4 1 10.2 0.1 5.4 5 0 0 5 5 5 2 Leucine Rich Repeat p450 PF00067.22 KXS22398.1 - 6e-10 38.4 0.1 1.5e-09 37.2 0.0 1.5 2 0 0 2 2 2 1 Cytochrome P450 Leu_zip PF15294.6 KXS22399.1 - 0.063 12.8 0.8 0.082 12.4 0.8 1.1 1 0 0 1 1 1 0 Leucine zipper p450 PF00067.22 KXS22400.1 - 2.9e-24 85.7 0.0 4.1e-24 85.2 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 RabGAP-TBC PF00566.18 KXS22401.1 - 3.9e-29 101.8 0.0 5.1e-26 91.7 0.0 2.5 2 1 0 2 2 2 2 Rab-GTPase-TBC domain CENP-Q PF13094.6 KXS22401.1 - 0.33 11.2 1.7 0.59 10.3 1.7 1.3 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit PIG-L PF02585.17 KXS22402.1 - 1.2e-07 32.4 0.1 2.5e-06 28.2 0.1 2.3 1 1 0 1 1 1 1 GlcNAc-PI de-N-acetylase DUF2862 PF11061.8 KXS22402.1 - 0.056 13.3 0.0 0.16 11.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2862) Ndc1_Nup PF09531.10 KXS22403.1 - 4.9 5.7 12.4 6.5 5.3 0.0 2.5 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup Mito_carr PF00153.27 KXS22404.1 - 6.2e-25 87.0 10.5 4.1e-11 42.7 0.4 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein RDD PF06271.12 KXS22404.1 - 0.0015 18.8 0.2 0.004 17.4 0.1 1.7 1 1 0 1 1 1 1 RDD family zf-MYND PF01753.18 KXS22405.1 - 7.2e-09 35.6 10.5 7.2e-09 35.6 10.5 3.1 3 0 0 3 3 3 1 MYND finger zf-C6H2 PF15801.5 KXS22405.1 - 0.31 11.4 17.4 2.5 8.5 8.3 3.9 3 1 0 3 3 3 0 zf-MYND-like zinc finger, mRNA-binding Metallophos PF00149.28 KXS22406.1 - 2.1e-40 139.4 0.0 2.8e-40 139.0 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KXS22406.1 - 1.4e-22 79.9 0.6 2.7e-22 79.0 0.3 1.7 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain TED PF08341.11 KXS22407.1 - 0.076 13.4 6.8 39 4.7 6.8 3.9 1 1 0 1 1 1 0 Thioester domain FokI_N PF02981.15 KXS22407.1 - 0.18 12.0 3.1 17 5.6 0.1 3.9 1 1 1 3 3 3 0 Restriction endonuclease FokI, recognition domain CHASE7 PF17151.4 KXS22407.1 - 0.39 10.3 18.9 1.2 8.8 0.1 5.6 3 1 3 7 7 7 0 Periplasmic sensor domain RVT_N PF13655.6 KXS22407.1 - 6.5 7.1 18.8 0.91 9.8 1.3 5.0 3 1 2 6 6 6 0 N-terminal domain of reverse transcriptase Adenine_glyco PF03352.13 KXS22408.1 - 1.6e-58 197.4 0.1 6.5e-58 195.4 0.1 1.8 1 1 0 1 1 1 1 Methyladenine glycosylase DUF3357 PF11837.8 KXS22408.1 - 0.17 12.3 1.7 0.35 11.3 1.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) RNA_pol_Rpc4 PF05132.14 KXS22408.1 - 2.5 8.5 6.1 3.2 8.1 4.4 1.9 2 0 0 2 2 2 0 RNA polymerase III RPC4 Aldo_ket_red PF00248.21 KXS22412.1 - 1.2e-57 195.4 0.0 1.4e-57 195.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Mtc PF03820.17 KXS22413.1 - 5.6e-99 331.1 0.1 6.3e-99 330.9 0.1 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier ABC_membrane PF00664.23 KXS22414.1 - 1.1e-68 231.9 30.9 1.2e-41 143.2 9.4 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KXS22414.1 - 2.1e-50 170.8 0.0 4.9e-27 95.1 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KXS22414.1 - 4e-07 29.7 2.8 0.02 14.3 0.0 3.8 2 2 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KXS22414.1 - 3.4e-05 24.3 5.3 0.063 13.7 0.1 2.9 3 0 0 3 3 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 KXS22414.1 - 0.00014 21.9 0.9 0.34 11.0 0.1 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 KXS22414.1 - 0.00014 21.5 1.0 0.15 11.8 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain MTABC_N PF16185.5 KXS22414.1 - 0.0014 18.2 5.1 0.0018 17.8 0.1 3.0 3 0 0 3 3 3 1 Mitochondrial ABC-transporter N-terminal five TM region DEAD PF00270.29 KXS22414.1 - 0.0045 16.8 0.2 0.038 13.8 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase IstB_IS21 PF01695.17 KXS22414.1 - 0.011 15.5 0.3 6.1 6.5 0.0 3.2 3 0 0 3 3 3 0 IstB-like ATP binding protein DUF87 PF01935.17 KXS22414.1 - 0.012 15.7 8.0 0.22 11.6 0.1 3.2 3 0 0 3 3 3 0 Helicase HerA, central domain RsgA_GTPase PF03193.16 KXS22414.1 - 0.026 14.4 2.7 0.53 10.2 0.4 2.4 2 0 0 2 2 2 0 RsgA GTPase AAA_24 PF13479.6 KXS22414.1 - 0.082 12.6 0.1 0.26 11.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 KXS22414.1 - 0.084 12.0 0.4 4.9 6.2 0.1 2.5 2 0 0 2 2 2 0 NB-ARC domain DUF815 PF05673.13 KXS22414.1 - 0.12 11.5 0.3 5.1 6.2 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 KXS22414.1 - 0.14 11.6 0.3 8.3 5.9 0.1 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_22 PF13401.6 KXS22414.1 - 0.2 11.9 4.4 12 6.2 0.2 3.3 2 1 0 2 2 2 0 AAA domain AIG1 PF04548.16 KXS22414.1 - 0.3 10.4 1.2 9.6 5.5 0.1 2.5 2 0 0 2 2 2 0 AIG1 family Ycf9 PF01737.17 KXS22414.1 - 3 7.8 12.8 0.027 14.3 1.6 2.9 2 0 0 2 2 2 0 YCF9 Zn_clus PF00172.18 KXS22415.1 - 7.1e-10 38.8 12.8 1.3e-09 38.0 12.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXS22415.1 - 3.7e-07 29.4 0.1 7.6e-06 25.1 0.1 2.2 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXS22416.1 - 1.4e-10 41.1 15.2 1.6e-10 40.9 15.2 1.1 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 KXS22417.1 - 0.0014 18.7 11.0 0.0029 17.7 11.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXS22417.1 - 0.0071 15.4 1.7 0.026 13.6 1.7 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain FOP_dimer PF09398.10 KXS22418.1 - 0.00035 20.8 0.0 0.00059 20.0 0.0 1.4 1 0 0 1 1 1 1 FOP N terminal dimerisation domain LisH_2 PF16045.5 KXS22418.1 - 0.047 12.7 0.0 0.086 11.9 0.0 1.3 1 0 0 1 1 1 0 LisH Rpp20 PF12328.8 KXS22420.1 - 4.2e-11 42.9 5.3 1.5e-09 38.0 0.2 2.9 2 2 0 2 2 2 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.21 KXS22420.1 - 1.6e-07 31.0 0.0 2.9e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Alba DUF1387 PF07139.11 KXS22420.1 - 0.052 13.3 5.3 0.06 13.1 5.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) DCP2 PF05026.13 KXS22421.1 - 1.4e-28 99.0 0.6 2.6e-28 98.1 0.6 1.5 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.28 KXS22421.1 - 1e-16 61.2 0.0 1.5e-16 60.6 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain zf-C2H2_8 PF15909.5 KXS22422.1 - 0.0047 17.2 0.6 0.011 16.0 0.1 1.7 1 1 1 2 2 2 1 C2H2-type zinc ribbon zf-C2H2 PF00096.26 KXS22422.1 - 0.0084 16.5 1.1 0.021 15.2 1.1 1.7 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXS22422.1 - 0.29 12.1 3.2 0.34 11.9 1.0 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger UQ_con PF00179.26 KXS22423.1 - 1.4e-48 164.1 0.0 1.6e-48 163.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KXS22423.1 - 1.6e-05 24.6 0.0 1.9e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 KXS22423.1 - 0.015 15.1 0.1 0.032 14.1 0.1 1.6 1 1 0 1 1 1 0 UEV domain RWD PF05773.22 KXS22423.1 - 0.13 12.6 0.1 0.23 11.8 0.1 1.6 1 1 0 1 1 1 0 RWD domain TauD PF02668.16 KXS22424.1 - 3.2e-51 174.7 0.0 3.9e-51 174.4 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Pam17 PF08566.10 KXS22425.1 - 5.5e-34 117.4 0.1 8.8e-34 116.7 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 Sporozoite_P67 PF05642.11 KXS22425.1 - 1.6 6.7 9.1 2.6 6.0 9.1 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RVT_1 PF00078.27 KXS22426.1 - 5.9e-08 32.5 0.0 1e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Mago_nashi PF02792.14 KXS22427.1 - 7.2e-77 256.3 0.2 8.2e-77 256.1 0.2 1.0 1 0 0 1 1 1 1 Mago nashi protein TauD PF02668.16 KXS22428.1 - 9.5e-37 127.2 0.2 1.5e-36 126.6 0.2 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 KXS22428.1 - 1.1e-11 45.2 0.0 2.7e-11 44.0 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF971) CsiD PF08943.10 KXS22428.1 - 0.0042 16.2 0.0 0.05 12.7 0.0 2.0 2 0 0 2 2 2 1 CsiD UBA PF00627.31 KXS22429.1 - 9.5e-09 35.0 0.2 1.6e-08 34.3 0.2 1.3 1 0 0 1 1 1 1 UBA/TS-N domain UBA_4 PF14555.6 KXS22429.1 - 0.0021 17.8 0.1 0.0031 17.3 0.1 1.3 1 0 0 1 1 1 1 UBA-like domain RuvA_C PF07499.13 KXS22429.1 - 0.012 16.1 0.7 0.018 15.5 0.7 1.3 1 0 0 1 1 1 0 RuvA, C-terminal domain Glyco_hydro_16 PF00722.21 KXS22431.1 - 1.5e-12 47.3 0.0 2.6e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 CoA_transf_3 PF02515.17 KXS22432.1 - 7.9e-79 265.4 0.1 1.4e-78 264.6 0.1 1.4 1 1 0 1 1 1 1 CoA-transferase family III Csm1_N PF18504.1 KXS22433.1 - 1.5 9.3 5.5 18 5.8 0.1 2.5 2 0 0 2 2 2 0 Csm1 N-terminal domain HisKA_3 PF07730.13 KXS22433.1 - 2.3 8.8 9.0 0.16 12.5 1.0 3.1 4 1 0 4 4 4 0 Histidine kinase Exonuc_VII_L PF02601.15 KXS22433.1 - 6.3 6.3 6.8 17 4.9 6.8 1.8 1 1 0 1 1 1 0 Exonuclease VII, large subunit C1_1 PF00130.22 KXS22434.1 - 2.1 8.3 9.9 0.11 12.4 0.6 2.5 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Glyco_trans_2_3 PF13632.6 KXS22435.1 - 1.1e-27 97.2 3.8 1.1e-27 97.2 3.8 2.4 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KXS22435.1 - 6.8e-26 91.6 0.0 1e-25 91.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Cellulose_synt PF03552.14 KXS22435.1 - 7e-26 91.0 7.8 7.5e-14 51.2 4.2 3.1 1 1 2 3 3 3 3 Cellulose synthase Glycos_transf_2 PF00535.26 KXS22435.1 - 1.4e-20 73.8 0.0 2.2e-20 73.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KXS22435.1 - 1.4e-15 57.2 0.0 3e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 21 Chitin_synth_2 PF03142.15 KXS22435.1 - 0.23 10.0 4.0 0.34 9.5 0.2 2.6 3 0 0 3 3 3 0 Chitin synthase Glyco_hydro_16 PF00722.21 KXS22436.1 - 2.8e-09 36.7 0.0 9.4e-06 25.2 0.0 2.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 16 dCMP_cyt_deam_1 PF00383.23 KXS22437.1 - 7.6e-24 83.5 0.0 1.1e-23 83.1 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KXS22437.1 - 5.2e-17 61.9 0.0 1.7e-08 34.3 0.0 2.2 2 0 0 2 2 2 2 MafB19-like deaminase Bd3614-deam PF14439.6 KXS22437.1 - 0.016 15.3 0.4 0.044 13.9 0.4 1.7 1 1 0 1 1 1 0 Bd3614-like deaminase tRNA-synt_1b PF00579.25 KXS22438.1 - 2.5e-65 220.7 0.0 3.3e-65 220.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) tRNA_bind PF01588.20 KXS22438.1 - 3.5e-27 94.4 0.0 6.3e-27 93.5 0.0 1.4 1 0 0 1 1 1 1 Putative tRNA binding domain Cofilin_ADF PF00241.20 KXS22439.1 - 4.3e-32 110.5 0.0 8.9e-15 54.6 0.0 2.1 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein 2-oxoacid_dh PF00198.23 KXS22440.1 - 2.5e-67 226.7 0.0 3.7e-67 226.2 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KXS22440.1 - 1e-20 73.3 0.1 2.6e-20 72.0 0.1 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 KXS22440.1 - 4.7e-17 62.0 0.2 1e-16 61.0 0.2 1.6 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 KXS22440.1 - 9.2e-05 22.2 0.1 0.086 12.7 0.0 2.7 1 1 1 2 2 2 2 Biotin-lipoyl like HlyD_D23 PF16576.5 KXS22440.1 - 0.04 13.1 0.0 0.072 12.3 0.0 1.4 1 0 0 1 1 1 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion Transferase PF02458.15 KXS22440.1 - 0.095 11.3 0.4 0.62 8.6 0.1 2.0 2 0 0 2 2 2 0 Transferase family zf-C3HC4 PF00097.25 KXS22442.1 - 6.4e-08 32.3 9.7 1.5e-07 31.1 9.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXS22442.1 - 4.9e-07 29.5 11.3 1e-06 28.5 11.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXS22442.1 - 8.8e-07 29.2 9.7 2.1e-06 28.0 9.7 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KXS22442.1 - 6.5e-06 25.9 7.4 6.5e-06 25.9 7.4 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXS22442.1 - 2.4e-05 24.2 8.2 6.2e-05 22.9 8.2 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KXS22442.1 - 2.4e-05 24.3 9.0 6.1e-05 23.0 9.0 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KXS22442.1 - 4.1e-05 23.6 10.2 8.4e-05 22.6 10.2 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KXS22442.1 - 0.00016 21.5 9.5 0.00031 20.5 9.5 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 DUF3450 PF11932.8 KXS22442.1 - 0.00016 21.1 5.9 0.00016 21.1 5.9 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF3450) zf-ANAPC11 PF12861.7 KXS22442.1 - 0.00045 20.2 2.7 0.0011 18.9 2.7 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger DivIC PF04977.15 KXS22442.1 - 0.00048 19.8 14.4 0.13 12.1 5.5 3.4 2 1 1 3 3 3 2 Septum formation initiator zf-rbx1 PF12678.7 KXS22442.1 - 0.00049 20.3 5.7 0.0016 18.6 5.7 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain Golgin_A5 PF09787.9 KXS22442.1 - 0.0005 19.6 9.4 0.00082 18.9 9.4 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 5 Filament PF00038.21 KXS22442.1 - 0.0084 15.7 8.9 0.014 15.0 8.9 1.4 1 0 0 1 1 1 1 Intermediate filament protein HALZ PF02183.18 KXS22442.1 - 0.0089 16.2 20.3 0.029 14.6 4.6 4.7 4 1 1 5 5 5 2 Homeobox associated leucine zipper DUF874 PF05917.11 KXS22442.1 - 0.016 14.3 7.6 0.024 13.7 7.6 1.2 1 0 0 1 1 1 0 Helicobacter pylori protein of unknown function (DUF874) Spc7 PF08317.11 KXS22442.1 - 0.017 14.0 14.4 0.03 13.2 14.4 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein CENP-F_leu_zip PF10473.9 KXS22442.1 - 0.017 15.1 19.7 0.018 15.1 6.8 2.4 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4407 PF14362.6 KXS22442.1 - 0.022 14.1 13.4 0.045 13.1 13.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Takusan PF04822.13 KXS22442.1 - 0.032 14.1 0.2 0.032 14.1 0.2 2.6 2 1 0 2 2 2 0 Takusan Seryl_tRNA_N PF02403.22 KXS22442.1 - 0.084 13.1 15.2 0.066 13.5 2.6 2.7 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain APG6_N PF17675.1 KXS22442.1 - 0.17 12.4 27.6 0.033 14.7 7.7 2.8 2 1 1 3 3 2 0 Apg6 coiled-coil region Baculo_IE-1 PF05290.11 KXS22442.1 - 0.3 11.0 1.5 0.56 10.1 1.5 1.3 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) UPF0242 PF06785.11 KXS22442.1 - 0.3 11.2 8.8 0.53 10.4 8.8 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus HOOK PF05622.12 KXS22442.1 - 0.37 8.9 20.5 0.71 8.0 3.9 2.4 1 1 1 2 2 2 0 HOOK protein GAS PF13851.6 KXS22442.1 - 0.59 9.4 15.0 0.32 10.3 8.7 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding zf-RING_10 PF16685.5 KXS22442.1 - 0.67 10.1 6.7 1.5 9.0 6.7 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 KASH_CCD PF14662.6 KXS22442.1 - 1.2 8.9 15.9 2.7 7.8 15.9 1.5 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH HUN PF08729.10 KXS22442.1 - 1.5 8.9 13.3 0.22 11.6 8.6 2.1 2 0 0 2 2 1 0 HPC2 and ubinuclein domain Macoilin PF09726.9 KXS22442.1 - 1.9 6.9 9.3 2.9 6.3 9.3 1.2 1 0 0 1 1 1 0 Macoilin family TLE_N PF03920.15 KXS22442.1 - 2.7 8.1 5.6 2.4 8.3 0.8 2.5 1 1 0 2 2 2 0 Groucho/TLE N-terminal Q-rich domain ERM PF00769.19 KXS22442.1 - 3.1 7.6 22.9 11 5.8 23.0 1.8 1 1 0 1 1 1 0 Ezrin/radixin/moesin family zf-RING_4 PF14570.6 KXS22442.1 - 3.7 7.4 11.9 0.37 10.6 4.4 2.5 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Fungal_TACC PF12709.7 KXS22442.1 - 4.3 7.8 7.6 4.2 7.9 0.1 2.9 2 1 0 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins HAUS-augmin3 PF14932.6 KXS22442.1 - 4.8 6.7 14.3 11 5.5 14.1 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 Atg14 PF10186.9 KXS22442.1 - 5.2 6.1 13.0 10 5.1 13.0 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Metal_resist PF13801.6 KXS22442.1 - 5.6 7.2 12.1 7 6.9 5.2 3.1 3 0 0 3 3 2 0 Heavy-metal resistance YabA PF06156.13 KXS22442.1 - 8.3 7.1 8.7 21 5.8 1.4 2.8 1 1 1 2 2 2 0 Initiation control protein YabA JIP_LZII PF16471.5 KXS22442.1 - 8.6 6.6 16.8 1.2 9.3 5.0 3.4 1 1 2 3 3 3 0 JNK-interacting protein leucine zipper II ZapB PF06005.12 KXS22442.1 - 9.2 6.8 19.1 10 6.7 2.6 3.5 1 1 1 2 2 2 0 Cell division protein ZapB Aconitase PF00330.20 KXS22443.1 - 1.5e-145 485.8 0.0 2e-145 485.4 0.0 1.2 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KXS22443.1 - 2.4e-39 134.6 0.0 3.9e-39 134.0 0.0 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF3939 PF13075.6 KXS22443.1 - 0.25 11.4 0.0 0.48 10.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3939) TPR_14 PF13428.6 KXS22444.1 - 0.15 13.0 0.1 29 5.8 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat DMRL_synthase PF00885.19 KXS22445.1 - 1.1e-52 177.6 0.3 1.3e-52 177.4 0.3 1.0 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase TPR_1 PF00515.28 KXS22446.1 - 1.1e-17 63.0 6.3 1.1e-09 37.6 0.1 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KXS22446.1 - 5.7e-14 51.0 6.5 2.1e-07 30.5 0.1 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 KXS22446.1 - 1.2e-10 40.7 3.9 5.3e-08 32.5 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 KXS22446.1 - 1e-09 38.9 0.5 9.1e-07 29.4 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 KXS22446.1 - 8.4e-06 26.1 3.8 0.0094 16.5 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 KXS22446.1 - 1.3e-05 24.7 0.5 0.03 14.0 0.0 3.3 2 1 1 3 3 3 2 TPR repeat TPR_9 PF13371.6 KXS22446.1 - 2.9e-05 24.1 0.1 7e-05 22.9 0.1 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 KXS22446.1 - 5.3e-05 23.7 1.8 0.017 15.9 0.0 3.0 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 KXS22446.1 - 6.2e-05 23.2 2.6 0.06 13.6 0.0 3.0 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 KXS22446.1 - 0.00038 20.6 1.6 5.5 7.6 0.0 4.1 4 1 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KXS22446.1 - 0.0018 18.5 2.9 0.016 15.4 0.4 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 KXS22446.1 - 0.0034 17.9 4.6 0.7 10.4 0.3 3.3 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 KXS22446.1 - 0.0034 17.3 0.0 24 5.2 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 KXS22446.1 - 0.0058 16.5 0.4 1.2 9.1 0.0 2.9 2 1 0 2 2 2 1 Tetratricopeptide repeat Mo25 PF08569.11 KXS22447.1 - 1.5e-132 441.9 18.9 2.8e-109 365.5 7.3 2.0 2 0 0 2 2 2 2 Mo25-like Lipocalin_7 PF14651.6 KXS22447.1 - 0.0041 17.0 0.0 0.0085 16.0 0.0 1.5 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Profilin PF00235.19 KXS22448.1 - 1.5e-47 161.1 0.0 1.6e-47 160.9 0.0 1.0 1 0 0 1 1 1 1 Profilin Robl_LC7 PF03259.17 KXS22448.1 - 0.076 12.8 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Roadblock/LC7 domain SMAP PF15477.6 KXS22449.1 - 1.6e-09 38.6 0.0 1.6e-09 38.6 0.0 4.8 2 1 0 2 2 2 1 Small acidic protein family VHS PF00790.19 KXS22450.1 - 4.7e-27 94.6 0.0 1.5e-26 92.9 0.0 1.9 2 0 0 2 2 2 1 VHS domain GAT PF03127.14 KXS22450.1 - 6.7e-12 45.5 1.7 2.7e-11 43.6 0.3 2.5 2 0 0 2 2 2 1 GAT domain GGA_N-GAT PF18308.1 KXS22450.1 - 0.00027 20.5 0.3 0.00065 19.3 0.3 1.7 1 0 0 1 1 1 1 GGA N-GAT domain CbiZ PF01955.18 KXS22451.1 - 0.019 15.0 0.1 0.034 14.2 0.1 1.4 1 0 0 1 1 1 0 Adenosylcobinamide amidohydrolase ADK PF00406.22 KXS22452.1 - 8.1e-50 168.8 0.0 1e-49 168.5 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KXS22452.1 - 2.9e-20 73.1 0.0 8.2e-20 71.6 0.0 1.7 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.14 KXS22452.1 - 2.7e-14 52.9 0.0 4.8e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 KXS22452.1 - 2.7e-06 27.9 0.0 5.3e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KXS22452.1 - 0.00041 20.5 0.0 0.0012 19.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 KXS22452.1 - 0.0029 17.3 0.3 0.21 11.3 0.1 2.2 2 0 0 2 2 2 1 Thymidylate kinase dNK PF01712.19 KXS22452.1 - 0.0057 16.5 0.1 1 9.2 0.0 2.8 3 0 0 3 3 3 1 Deoxynucleoside kinase Zeta_toxin PF06414.12 KXS22452.1 - 0.035 13.4 0.1 0.064 12.5 0.1 1.4 1 0 0 1 1 1 0 Zeta toxin Caerin_1 PF07440.12 KXS22452.1 - 0.092 12.8 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 Caerin 1 protein PRMT5 PF05185.16 KXS22453.1 - 4.7e-65 218.7 0.0 6.6e-65 218.2 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_TIM PF17285.2 KXS22453.1 - 8.6e-49 166.0 0.0 1.5e-48 165.3 0.0 1.3 1 0 0 1 1 1 1 PRMT5 TIM barrel domain PRMT5_C PF17286.2 KXS22453.1 - 2.6e-47 161.0 0.4 4.8e-47 160.1 0.1 1.6 2 0 0 2 2 2 1 PRMT5 oligomerisation domain BLOC1_2 PF10046.9 KXS22454.1 - 0.032 14.5 5.0 0.38 11.1 0.0 4.0 4 1 1 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 YscO PF07321.12 KXS22454.1 - 0.033 14.1 0.0 0.033 14.1 0.0 4.8 3 1 2 5 5 5 0 Type III secretion protein YscO IFT20 PF14931.6 KXS22454.1 - 0.035 14.3 1.0 0.035 14.3 1.0 3.3 3 1 0 3 3 3 0 Intraflagellar transport complex B, subunit 20 FAM76 PF16046.5 KXS22454.1 - 0.63 9.4 8.0 0.091 12.1 3.1 2.0 2 0 0 2 2 2 0 FAM76 protein Baculo_PEP_C PF04513.12 KXS22454.1 - 1.3 9.1 8.3 9.9 6.2 0.0 2.8 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Cnn_1N PF07989.11 KXS22454.1 - 3.2 8.0 10.0 6.7 7.0 0.0 4.8 4 2 0 4 4 4 0 Centrosomin N-terminal motif 1 IMD PF08397.11 KXS22454.1 - 3.8 6.8 11.8 2.7 7.3 0.6 2.8 3 1 0 3 3 3 0 IRSp53/MIM homology domain Rab5-bind PF09311.11 KXS22454.1 - 5.6 6.3 17.0 0.32 10.3 7.1 3.0 2 1 1 3 3 3 0 Rabaptin-like protein 2Fe-2S_thioredx PF01257.19 KXS22455.1 - 1.2e-56 190.7 0.2 1.4e-56 190.3 0.2 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin RNA_pol_Rpb6 PF01192.22 KXS22456.1 - 6.2e-16 58.1 0.1 9.3e-16 57.5 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb6 Ank_2 PF12796.7 KXS22457.1 - 4.9e-33 113.6 0.1 2.4e-13 50.5 0.0 3.8 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXS22457.1 - 2e-32 111.1 0.1 1.5e-11 44.5 0.0 3.8 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXS22457.1 - 1.1e-30 105.3 0.5 3e-08 33.7 0.0 4.8 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 KXS22457.1 - 6.7e-26 89.6 0.6 5.3e-07 29.8 0.0 5.8 7 0 0 7 7 7 5 Ankyrin repeat Ank_3 PF13606.6 KXS22457.1 - 2.2e-24 82.9 0.0 0.00035 20.8 0.0 5.8 6 0 0 6 6 6 5 Ankyrin repeat Amidohydro_2 PF04909.14 KXS22458.1 - 2e-21 77.0 1.8 5.1e-21 75.7 1.8 1.7 1 1 0 1 1 1 1 Amidohydrolase Acyl-CoA_dh_1 PF00441.24 KXS22459.1 - 8.2e-32 110.5 0.7 1.2e-31 110.0 0.7 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KXS22459.1 - 1.2e-17 63.9 0.0 2.1e-17 63.1 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KXS22459.1 - 1.9e-15 57.5 0.0 3.1e-15 56.8 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KXS22459.1 - 1.3e-11 44.9 2.5 2.1e-11 44.2 2.5 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_1 PF00441.24 KXS22460.1 - 2.3e-37 128.5 3.8 4.5e-37 127.6 3.8 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KXS22460.1 - 1.9e-18 66.5 0.0 3.4e-18 65.6 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KXS22460.1 - 1.1e-11 45.1 1.5 2e-11 44.3 1.5 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KXS22460.1 - 1.5e-11 45.0 0.1 8.6e-11 42.5 0.1 2.3 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain HpaB_N PF11794.8 KXS22460.1 - 0.01 15.5 0.0 0.019 14.6 0.0 1.4 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal BolA PF01722.18 KXS22461.1 - 1.7e-09 37.8 0.0 2.3e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 BolA-like protein DUF1326 PF07040.11 KXS22461.1 - 0.13 12.2 0.1 0.17 11.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1326) Aldedh PF00171.22 KXS22462.1 - 2.4e-170 567.0 0.0 7.2e-90 301.7 0.0 2.0 2 0 0 2 2 2 2 Aldehyde dehydrogenase family Cnl2_NKP2 PF09447.10 KXS22462.1 - 0.0013 18.9 0.5 2.2 8.5 0.1 2.4 2 0 0 2 2 2 2 Cnl2/NKP2 family protein Rotavirus_VP1 PF12289.8 KXS22462.1 - 0.002 17.2 0.1 0.37 9.8 0.0 2.3 2 0 0 2 2 2 2 Rotavirus VP1 C-terminal domain Nuf2 PF03800.14 KXS22463.1 - 5.8e-38 130.2 0.1 1.2e-37 129.1 0.1 1.6 1 0 0 1 1 1 1 Nuf2 family DHR10 PF18595.1 KXS22463.1 - 4.3e-20 71.9 13.9 4.3e-20 71.9 13.9 4.2 1 1 3 4 4 4 1 Designed helical repeat protein 10 domain DASH_Dad4 PF08650.10 KXS22463.1 - 0.056 13.4 0.1 17 5.5 0.0 2.9 2 0 0 2 2 2 0 DASH complex subunit Dad4 SIR2 PF02146.17 KXS22463.1 - 0.068 13.1 0.7 0.19 11.6 0.6 1.8 1 1 0 1 1 1 0 Sir2 family NPV_P10 PF05531.12 KXS22463.1 - 3.2 8.3 10.2 0.87 10.1 0.2 3.8 3 2 1 4 4 4 0 Nucleopolyhedrovirus P10 protein BLOC1_2 PF10046.9 KXS22463.1 - 3.2 8.1 25.6 0.44 10.9 0.4 5.3 3 2 0 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Gpr1_Fun34_YaaH PF01184.19 KXS22464.1 - 2.7e-36 125.2 21.5 3.5e-36 124.8 21.5 1.2 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family RseC_MucC PF04246.12 KXS22464.1 - 5.8 6.9 7.7 0.48 10.4 1.5 2.0 1 1 1 2 2 2 0 Positive regulator of sigma(E), RseC/MucC zf-C3HC4 PF00097.25 KXS22465.1 - 4.3e-10 39.3 4.3 8.1e-10 38.4 4.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KXS22465.1 - 1.2e-09 37.9 2.4 2.3e-09 37.0 2.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXS22465.1 - 1.7e-09 37.5 5.1 9.2e-09 35.2 3.7 2.5 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 KXS22465.1 - 5.7e-09 35.8 3.3 1e-08 35.0 3.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 KXS22465.1 - 7.7e-08 32.6 6.8 1.3e-07 31.8 6.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KXS22465.1 - 9.9e-07 28.5 5.3 2.2e-06 27.4 5.3 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KXS22465.1 - 1.3e-06 28.2 4.7 2.2e-06 27.4 4.7 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KXS22465.1 - 0.00012 22.2 7.6 0.00012 22.2 7.6 1.8 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 KXS22465.1 - 0.00012 22.3 4.5 0.00021 21.5 4.5 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KXS22465.1 - 0.0088 16.1 1.3 0.014 15.4 1.3 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Baculo_IE-1 PF05290.11 KXS22465.1 - 0.028 14.4 2.8 0.044 13.7 2.8 1.2 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-UDP PF14569.6 KXS22465.1 - 0.081 13.1 0.1 0.17 12.0 0.1 1.4 1 0 0 1 1 1 0 Zinc-binding RING-finger Rtf2 PF04641.12 KXS22465.1 - 0.12 11.7 0.3 0.21 10.9 0.3 1.4 1 1 0 1 1 1 0 Rtf2 RING-finger DUF1180 PF06679.12 KXS22465.1 - 4 7.8 7.6 2.7 8.4 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) LigB PF02900.18 KXS22467.1 - 3.5e-33 114.8 0.0 4.4e-33 114.5 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase MapZ_C2 PF18708.1 KXS22467.1 - 0.15 12.3 0.0 0.34 11.2 0.0 1.6 1 0 0 1 1 1 0 MapZ extracellular C-terminal domain 2 Pkinase PF00069.25 KXS22468.1 - 1.3e-65 221.4 0.0 1.5e-65 221.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS22468.1 - 1e-28 100.3 0.0 2e-28 99.4 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KXS22468.1 - 4.6e-06 26.2 0.0 2e-05 24.1 0.0 2.0 2 1 0 2 2 2 1 Kinase-like APH PF01636.23 KXS22468.1 - 0.0067 16.4 0.1 1.2 9.0 0.0 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KXS22468.1 - 0.025 13.5 0.0 0.035 13.1 0.0 1.4 1 1 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 KXS22468.1 - 0.14 11.5 0.0 0.39 10.0 0.0 1.8 2 1 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family ADIP PF11559.8 KXS22469.1 - 0.01 15.9 6.5 0.018 15.1 6.5 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding SKA1 PF07160.12 KXS22469.1 - 0.064 13.1 0.1 0.064 13.1 0.1 1.6 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 EMP24_GP25L PF01105.24 KXS22469.1 - 0.074 13.0 0.9 0.11 12.4 0.9 1.2 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD UPF0242 PF06785.11 KXS22469.1 - 0.16 12.1 1.6 0.28 11.3 1.6 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Syntaxin-6_N PF09177.11 KXS22469.1 - 0.25 11.9 4.1 0.22 12.1 2.4 1.9 2 0 0 2 2 2 0 Syntaxin 6, N-terminal YabA PF06156.13 KXS22469.1 - 0.56 10.9 4.5 6.9 7.4 0.8 2.5 1 1 1 2 2 2 0 Initiation control protein YabA CENP-F_leu_zip PF10473.9 KXS22469.1 - 0.61 10.1 7.4 1.1 9.3 7.4 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PRKG1_interact PF15898.5 KXS22469.1 - 3.2 8.7 7.7 5.1 8.1 5.0 2.4 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain FUSC PF04632.12 KXS22469.1 - 3.3 6.1 6.4 4.6 5.6 6.4 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family SH3_9 PF14604.6 KXS22470.1 - 4.8e-09 35.9 0.2 2.3e-08 33.8 0.0 2.2 3 0 0 3 3 3 1 Variant SH3 domain SH3_1 PF00018.28 KXS22470.1 - 1.5e-06 27.7 0.0 3.2e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 SH3 domain Podoplanin PF05808.11 KXS22470.1 - 0.00022 21.3 2.1 0.00022 21.3 2.1 2.2 1 1 1 2 2 2 1 Podoplanin SH3_2 PF07653.17 KXS22470.1 - 0.0034 17.0 0.0 0.0059 16.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain TMEM154 PF15102.6 KXS22470.1 - 0.039 13.9 0.2 0.039 13.9 0.2 2.4 2 1 0 2 2 2 0 TMEM154 protein family DUF2627 PF11118.8 KXS22470.1 - 0.13 12.8 0.0 0.25 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2627) DUF5348 PF17295.2 KXS22470.1 - 0.22 11.5 0.0 0.37 10.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5348) Lebercilin PF15619.6 KXS22471.1 - 2.3e-05 24.1 18.4 2.3e-05 24.1 18.4 7.0 2 2 4 6 6 6 1 Ciliary protein causing Leber congenital amaurosis disease SRP54_N PF02881.19 KXS22471.1 - 0.00082 19.5 3.9 0.0067 16.6 2.1 3.6 2 0 0 2 2 2 1 SRP54-type protein, helical bundle domain HIP1_clath_bdg PF16515.5 KXS22471.1 - 0.0014 19.2 13.2 0.0014 19.2 13.2 11.0 2 2 10 12 12 12 1 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF4201 PF13870.6 KXS22471.1 - 0.002 17.9 13.2 0.002 17.9 13.2 8.2 3 3 3 6 6 6 2 Domain of unknown function (DUF4201) DUF745 PF05335.13 KXS22471.1 - 0.0032 17.2 0.5 0.0032 17.2 0.5 7.7 3 2 4 8 8 8 3 Protein of unknown function (DUF745) RHS_repeat PF05593.14 KXS22472.1 - 0.1 13.1 0.3 27 5.4 0.1 2.9 2 0 0 2 2 2 0 RHS Repeat DEC-1_N PF04625.13 KXS22472.1 - 0.39 9.7 30.0 0.18 10.8 7.4 2.5 2 0 0 2 2 2 0 DEC-1 protein, N-terminal region DOPA_dioxygen PF08883.11 KXS22473.1 - 1.5e-30 105.5 0.1 2.2e-30 105.0 0.1 1.2 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family Fungal_trans PF04082.18 KXS22474.1 - 8.7e-13 47.9 4.3 7.5e-09 35.0 0.0 3.1 3 0 0 3 3 3 2 Fungal specific transcription factor domain 2OG-FeII_Oxy_3 PF13640.6 KXS22475.1 - 7.5e-05 23.6 0.0 0.00014 22.7 0.0 1.5 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily GAS PF13851.6 KXS22476.1 - 3.6e-31 108.1 5.7 3.6e-31 108.1 5.7 3.2 1 1 2 3 3 3 1 Growth-arrest specific micro-tubule binding Phasin PF05597.11 KXS22476.1 - 5.2 7.1 20.5 0.091 12.8 8.3 3.3 3 1 1 4 4 4 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF4793 PF16041.5 KXS22477.1 - 0.12 12.5 0.0 0.31 11.2 0.0 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4793) GST_N_3 PF13417.6 KXS22479.1 - 1.4e-13 51.1 0.0 3e-13 50.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KXS22479.1 - 1.9e-07 31.3 0.0 3.7e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KXS22479.1 - 3.3e-07 30.2 0.2 6.8e-07 29.2 0.2 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF2599 PF10783.9 KXS22479.1 - 0.068 13.8 0.0 0.12 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2599) GST_N_4 PF17172.4 KXS22479.1 - 0.069 13.9 0.0 0.4 11.4 0.0 2.2 2 1 0 2 2 2 0 Glutathione S-transferase N-terminal domain ECH_1 PF00378.20 KXS22480.1 - 1e-35 123.3 0.0 2.2e-35 122.2 0.0 1.5 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXS22480.1 - 4.4e-19 69.1 0.0 5.3e-19 68.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase MFS_1 PF07690.16 KXS22481.1 - 1.1e-38 133.1 25.5 1.3e-38 132.9 25.5 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXS22481.1 - 0.00023 20.2 13.3 0.0018 17.2 13.3 2.6 1 1 0 1 1 1 1 Sugar (and other) transporter CPP1-like PF11833.8 KXS22481.1 - 0.0052 16.5 2.9 0.0052 16.5 2.9 2.4 1 1 1 2 2 2 1 Protein CHAPERONE-LIKE PROTEIN OF POR1-like WD40 PF00400.32 KXS22482.1 - 9.2e-52 171.9 24.0 7.8e-09 36.0 0.3 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXS22482.1 - 4.7e-12 46.0 1.2 0.038 14.3 0.0 5.1 3 2 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KXS22482.1 - 6.8e-06 25.0 5.6 0.24 10.0 0.1 4.8 2 1 3 5 5 5 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KXS22482.1 - 0.00061 18.8 0.9 2.5 7.0 0.1 4.4 2 2 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KXS22482.1 - 0.00062 19.7 0.1 0.0078 16.1 0.0 2.4 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 KXS22482.1 - 0.0069 15.0 0.1 1.5 7.2 0.1 2.3 2 1 0 2 2 2 2 Cytochrome D1 heme domain DUF1513 PF07433.11 KXS22482.1 - 0.0074 15.4 0.0 0.41 9.7 0.0 2.6 2 1 1 3 3 3 1 Protein of unknown function (DUF1513) WD40_like PF17005.5 KXS22482.1 - 0.02 14.2 0.0 0.82 8.9 0.0 2.4 3 0 0 3 3 3 0 WD40-like domain PD40 PF07676.12 KXS22482.1 - 0.21 11.6 3.6 9.6 6.3 0.1 4.4 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat SET PF00856.28 KXS22483.1 - 1e-05 26.0 0.5 2.6e-05 24.7 0.1 1.8 2 0 0 2 2 2 1 SET domain Cwf_Cwc_15 PF04889.12 KXS22483.1 - 0.0055 16.5 7.2 0.011 15.4 7.2 1.5 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 KXS22483.1 - 0.013 13.7 1.4 0.02 13.2 1.4 1.3 1 0 0 1 1 1 0 Nop14-like family Myc_N PF01056.18 KXS22483.1 - 0.027 14.4 2.1 0.071 13.0 2.1 1.6 1 0 0 1 1 1 0 Myc amino-terminal region NOA36 PF06524.12 KXS22483.1 - 0.5 9.6 12.7 0.91 8.8 12.7 1.4 1 0 0 1 1 1 0 NOA36 protein PBP1_TM PF14812.6 KXS22483.1 - 0.7 10.3 9.9 0.2 12.0 6.1 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal SDA1 PF05285.12 KXS22483.1 - 3.3 7.0 9.3 6.6 6.1 9.3 1.4 1 0 0 1 1 1 0 SDA1 DUF2076 PF09849.9 KXS22483.1 - 9.3 6.2 10.2 17 5.4 10.2 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) DAO PF01266.24 KXS22484.1 - 4e-36 125.3 0.8 4.6e-36 125.1 0.8 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KXS22484.1 - 8.5e-05 21.8 2.5 0.00022 20.4 2.5 1.6 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KXS22484.1 - 0.00017 21.7 0.7 0.00047 20.3 0.7 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KXS22484.1 - 0.00052 19.3 0.2 0.00096 18.5 0.2 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 KXS22484.1 - 0.0085 15.4 0.5 0.022 14.0 0.2 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXS22484.1 - 0.018 15.0 1.0 0.055 13.5 0.1 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding HI0933_like PF03486.14 KXS22484.1 - 0.021 13.6 1.6 10 4.7 0.0 3.0 3 0 0 3 3 3 0 HI0933-like protein GIDA PF01134.22 KXS22484.1 - 0.024 13.8 0.3 0.04 13.0 0.3 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_binding_3 PF01494.19 KXS22484.1 - 0.034 13.4 0.2 0.051 12.8 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 KXS22484.1 - 0.081 12.2 0.0 5.5 6.1 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KXS22484.1 - 0.1 11.7 0.7 0.16 11.0 0.7 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Abhydrolase_3 PF07859.13 KXS22485.1 - 4.5e-44 150.8 0.0 5.8e-44 150.5 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KXS22485.1 - 1.1e-11 44.2 0.0 1.5e-11 43.8 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_2 PF02230.16 KXS22485.1 - 0.011 15.5 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase COesterase PF00135.28 KXS22485.1 - 0.025 13.5 0.0 0.038 12.9 0.0 1.2 1 0 0 1 1 1 0 Carboxylesterase family Hydrolase_4 PF12146.8 KXS22485.1 - 0.067 12.4 0.0 1.8 7.8 0.0 2.5 2 1 0 2 2 2 0 Serine aminopeptidase, S33 Med18 PF09637.10 KXS22486.1 - 7.4e-06 26.0 0.0 0.015 15.1 0.0 2.2 2 0 0 2 2 2 2 Med18 protein adh_short PF00106.25 KXS22488.1 - 2.1e-30 105.6 0.1 9.7e-30 103.5 0.1 2.0 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXS22488.1 - 1.5e-21 77.0 0.3 2.7e-20 72.9 0.2 2.9 2 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXS22488.1 - 7.6e-07 29.2 0.3 1.6e-06 28.2 0.3 1.5 1 1 0 1 1 1 1 KR domain Far-17a_AIG1 PF04750.14 KXS22490.1 - 0.039 13.2 29.4 0.091 12.1 29.3 1.7 1 1 0 1 1 1 0 FAR-17a/AIG1-like protein PRP38_assoc PF12871.7 KXS22492.1 - 0.012 16.2 29.6 0.012 16.2 29.6 8.3 6 2 2 8 8 8 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Glyco_hydro_106 PF17132.4 KXS22493.1 - 2.1e-16 59.4 0.1 6.9e-12 44.5 0.1 2.1 2 0 0 2 2 2 2 alpha-L-rhamnosidase MatB PF16449.5 KXS22493.1 - 0.027 14.3 2.2 0.088 12.6 0.1 2.7 3 0 0 3 3 3 0 Fimbrillin MatB DMRL_synthase PF00885.19 KXS22493.1 - 0.13 12.1 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 6,7-dimethyl-8-ribityllumazine synthase HIG_1_N PF04588.13 KXS22494.1 - 0.00072 19.7 0.0 0.0014 18.8 0.0 1.5 1 0 0 1 1 1 1 Hypoxia induced protein conserved region CX9C PF16860.5 KXS22494.1 - 0.0025 17.8 0.1 0.0082 16.1 0.0 1.7 2 0 0 2 2 2 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Cu_amine_oxid PF01179.20 KXS22495.1 - 3.2e-110 368.8 0.3 4.3e-110 368.5 0.3 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain DUF1965 PF09248.10 KXS22495.1 - 1.5e-12 47.1 0.1 7e-12 44.9 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1965) Cu_amine_oxidN2 PF02727.16 KXS22495.1 - 0.038 14.2 0.0 0.089 13.0 0.0 1.6 1 0 0 1 1 1 0 Copper amine oxidase, N2 domain Aminotran_1_2 PF00155.21 KXS22496.1 - 1.5e-53 182.3 0.0 1.9e-53 182.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II MerR-DNA-bind PF09278.11 KXS22496.1 - 0.17 12.4 0.0 3 8.4 0.0 2.3 2 0 0 2 2 2 0 MerR, DNA binding HTH_3 PF01381.22 KXS22497.1 - 8e-14 51.4 0.4 1.4e-13 50.7 0.4 1.3 1 0 0 1 1 1 1 Helix-turn-helix MBF1 PF08523.10 KXS22497.1 - 5.1e-08 33.3 8.2 1.3e-05 25.5 4.9 3.0 2 2 0 2 2 2 1 Multiprotein bridging factor 1 HTH_31 PF13560.6 KXS22497.1 - 1e-05 25.8 0.0 1.4e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 KXS22497.1 - 0.00088 19.2 0.3 0.0015 18.5 0.3 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain MqsA_antitoxin PF15731.5 KXS22497.1 - 0.1 12.7 0.2 0.12 12.5 0.2 1.2 1 0 0 1 1 1 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA Zn_clus PF00172.18 KXS22498.1 - 1.1e-07 31.9 10.7 1.8e-07 31.1 10.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_M24 PF00557.24 KXS22499.1 - 1.6e-18 67.1 0.1 2.2e-18 66.7 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP-binding PF00501.28 KXS22500.1 - 1.5e-54 185.3 0.0 1.9e-54 184.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXS22500.1 - 3.3e-10 40.8 0.1 6.8e-10 39.8 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Peripla_BP_4 PF13407.6 KXS22500.1 - 0.025 14.2 0.1 0.052 13.1 0.1 1.5 1 0 0 1 1 1 0 Periplasmic binding protein domain PALP PF00291.25 KXS22501.1 - 5.7e-68 229.5 2.9 6.8e-68 229.2 2.9 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF1688 PF07958.11 KXS22502.1 - 1.1e-127 426.2 0.0 7.6e-126 420.2 0.0 2.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1688) DOMON PF03351.17 KXS22503.1 - 7.7e-13 48.8 0.4 1.3e-12 48.0 0.4 1.4 1 0 0 1 1 1 1 DOMON domain Cyt-b5 PF00173.28 KXS22503.1 - 3.5e-10 39.9 0.0 8e-10 38.7 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FAD_binding_6 PF00970.24 KXS22503.1 - 4.4e-08 33.4 0.0 6.6e-07 29.6 0.0 2.6 1 1 1 2 2 2 1 Oxidoreductase FAD-binding domain Cytochrom_B561 PF03188.16 KXS22503.1 - 0.0021 18.2 8.0 0.0049 17.0 8.0 1.7 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 NAD_binding_1 PF00175.21 KXS22503.1 - 0.0022 18.6 0.0 0.0045 17.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Kinesin PF00225.23 KXS22505.1 - 1.6e-100 336.3 0.0 2.5e-100 335.7 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KXS22505.1 - 5.4e-19 68.6 0.0 1.3e-18 67.3 0.0 1.7 1 1 0 1 1 1 1 Microtubule binding FHA PF00498.26 KXS22505.1 - 9e-08 32.4 0.5 7.8e-07 29.3 0.2 2.5 2 0 0 2 2 2 1 FHA domain Kinesin_assoc PF16183.5 KXS22505.1 - 6.5e-05 23.2 15.2 0.013 15.6 3.6 4.1 3 1 1 4 4 4 2 Kinesin-associated C2 PF00168.30 KXS22505.1 - 0.12 12.7 0.0 0.75 10.1 0.0 2.2 2 0 0 2 2 2 0 C2 domain DUF4140 PF13600.6 KXS22505.1 - 0.14 12.6 7.9 6.4 7.3 2.3 3.6 2 2 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) SlyX PF04102.12 KXS22505.1 - 0.78 10.4 10.2 3.7 8.3 2.2 4.2 4 0 0 4 4 4 0 SlyX GAS PF13851.6 KXS22505.1 - 1.4 8.2 17.6 5.3 6.4 7.4 3.9 4 0 0 4 4 4 0 Growth-arrest specific micro-tubule binding DUF5082 PF16888.5 KXS22505.1 - 2 8.7 14.2 3.8 7.8 0.0 3.8 4 0 0 4 4 3 0 Domain of unknown function (DUF5082) UPF0242 PF06785.11 KXS22505.1 - 2.7 8.0 13.3 1.4 9.0 5.0 3.8 4 0 0 4 4 4 0 Uncharacterised protein family (UPF0242) N-terminus FliJ PF02050.16 KXS22505.1 - 4.5 7.5 10.9 8.1 6.7 3.1 3.2 3 0 0 3 3 2 0 Flagellar FliJ protein SNF2_N PF00176.23 KXS22506.1 - 8.7e-56 189.1 0.6 1.9e-55 188.0 0.2 1.6 1 1 1 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KXS22506.1 - 1.1e-16 61.1 0.0 2.1e-16 60.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Chromo PF00385.24 KXS22506.1 - 5.2e-14 51.9 0.6 7.5e-11 41.8 0.1 2.8 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain ResIII PF04851.15 KXS22506.1 - 4.9e-08 33.2 0.0 9.4e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CHDCT2 PF08074.11 KXS22506.1 - 0.017 15.3 0.3 0.075 13.2 0.1 2.2 2 0 0 2 2 2 0 CHDCT2 (NUC038) domain HDA2-3 PF11496.8 KXS22506.1 - 0.12 11.5 0.0 0.28 10.3 0.0 1.6 1 0 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 Chromo_shadow PF01393.19 KXS22506.1 - 0.15 12.2 0.0 0.37 10.9 0.0 1.6 1 0 0 1 1 1 0 Chromo shadow domain DUF3395 PF11875.8 KXS22506.1 - 0.17 11.8 1.3 0.59 10.0 1.3 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3395) AAA_11 PF13086.6 KXS22506.1 - 0.74 9.6 4.7 3.5 7.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain WD40 PF00400.32 KXS22507.1 - 1.8e-27 95.0 15.2 4.6e-06 27.3 0.3 6.9 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXS22507.1 - 2.4e-05 24.5 0.0 6 7.2 0.0 4.8 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KXS22507.1 - 0.11 11.1 0.1 5.9 5.4 0.0 3.0 4 0 0 4 4 4 0 Nucleoporin Nup120/160 Cyclin_N PF00134.23 KXS22508.1 - 5.4e-38 129.6 1.7 2.1e-37 127.7 0.1 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KXS22508.1 - 4.2e-10 39.7 0.1 1.1e-09 38.4 0.0 1.6 2 0 0 2 2 2 1 Cyclin, C-terminal domain Carb_kinase PF01256.17 KXS22509.1 - 1.3e-51 175.4 0.0 1.7e-51 175.1 0.0 1.1 1 0 0 1 1 1 1 Carbohydrate kinase Phos_pyr_kin PF08543.12 KXS22509.1 - 0.0019 17.6 0.0 0.0034 16.8 0.0 1.4 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Ribosomal_L11_N PF03946.14 KXS22511.1 - 1.3e-22 79.4 0.5 2e-22 78.8 0.5 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 KXS22511.1 - 2.6e-16 59.9 1.2 2.6e-16 59.9 1.2 1.5 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain HnRNP_M PF11532.8 KXS22511.1 - 0.034 14.4 0.8 0.064 13.5 0.8 1.4 1 0 0 1 1 1 0 Heterogeneous nuclear ribonucleoprotein M CRM1_C PF08767.11 KXS22512.1 - 7.8e-129 429.4 5.3 1.9e-128 428.1 1.6 2.7 2 0 0 2 2 2 1 CRM1 C terminal Xpo1 PF08389.12 KXS22512.1 - 6e-37 127.0 9.7 1.3e-36 125.9 6.9 3.1 3 0 0 3 3 3 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 KXS22512.1 - 2.1e-31 107.4 7.5 2.3e-31 107.2 4.7 2.6 2 0 0 2 2 2 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 KXS22512.1 - 1.9e-28 98.3 1.7 3.2e-27 94.4 0.9 2.9 2 0 0 2 2 2 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 KXS22512.1 - 3e-18 65.0 0.4 6.3e-18 64.0 0.4 1.6 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 KXS22512.1 - 4.1e-12 45.8 0.3 2.3e-11 43.4 0.3 2.4 2 0 0 2 2 2 1 Importin-beta N-terminal domain COX15-CtaA PF02628.15 KXS22513.1 - 6.1e-107 357.4 3.3 7.3e-107 357.2 3.3 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein Tox-HNH-HHH PF15637.6 KXS22513.1 - 0.082 13.1 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif ADH_N PF08240.12 KXS22514.1 - 5.5e-26 90.6 0.9 5.5e-26 90.6 0.9 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXS22514.1 - 2.5e-20 72.8 2.3 4.1e-20 72.1 2.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PrmA PF06325.13 KXS22514.1 - 0.016 14.6 1.1 0.026 13.9 1.1 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) NAD_binding_2 PF03446.15 KXS22514.1 - 0.053 13.7 1.7 0.18 12.0 0.9 2.1 1 1 1 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 KXS22514.1 - 0.068 13.0 1.2 0.12 12.3 0.4 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain zf-C2HC_2 PF13913.6 KXS22515.1 - 6.7e-16 57.8 16.5 5e-08 32.6 0.5 4.1 4 0 0 4 4 4 3 zinc-finger of a C2HC-type zf-Di19 PF05605.12 KXS22515.1 - 5.1e-05 23.5 6.1 0.0045 17.2 0.7 3.5 3 0 0 3 3 3 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.26 KXS22515.1 - 0.00017 21.8 21.5 0.0073 16.7 0.1 5.2 4 1 1 5 5 5 2 Zinc finger, C2H2 type Sgf11 PF08209.11 KXS22515.1 - 0.00021 20.8 11.6 0.068 12.7 0.5 3.7 3 0 0 3 3 3 2 Sgf11 (transcriptional regulation protein) zinc_ribbon_15 PF17032.5 KXS22515.1 - 0.00096 19.9 8.5 0.047 14.5 0.6 3.2 3 0 0 3 3 3 2 zinc-ribbon family zf-C2H2_4 PF13894.6 KXS22515.1 - 0.012 16.4 27.8 0.026 15.4 0.5 4.7 4 1 1 5 5 5 0 C2H2-type zinc finger DZR PF12773.7 KXS22515.1 - 0.015 15.3 20.0 0.018 15.1 1.7 3.9 3 1 0 3 3 3 0 Double zinc ribbon Rad50_zn_hook PF04423.14 KXS22515.1 - 0.018 14.9 1.0 3.6 7.5 0.0 3.2 3 0 0 3 3 3 0 Rad50 zinc hook motif zf-ribbon_3 PF13248.6 KXS22515.1 - 0.028 13.8 17.5 1.9 8.0 5.6 4.5 4 0 0 4 4 4 0 zinc-ribbon domain zf-C2H2_jaz PF12171.8 KXS22515.1 - 0.039 14.2 14.2 0.98 9.8 0.2 4.7 4 2 0 4 4 4 0 Zinc-finger double-stranded RNA-binding c-SKI_SMAD_bind PF08782.10 KXS22515.1 - 0.12 12.6 4.9 13 6.1 0.0 3.2 2 1 1 3 3 3 0 c-SKI Smad4 binding domain zf-H2C2_2 PF13465.6 KXS22515.1 - 0.13 12.7 9.2 4 8.0 0.0 4.0 4 0 0 4 4 4 0 Zinc-finger double domain zinc_ribbon_9 PF14369.6 KXS22515.1 - 1.4 9.2 13.1 3 8.2 0.1 4.3 4 1 1 5 5 5 0 zinc-ribbon zinc_ribbon_2 PF13240.6 KXS22515.1 - 1.9 8.3 26.3 1.1 9.1 11.6 4.4 4 0 0 4 4 4 0 zinc-ribbon domain WES_acyltransf PF03007.16 KXS22517.1 - 1.1e-20 74.6 0.0 3.8e-18 66.2 0.0 2.3 2 0 0 2 2 2 2 Wax ester synthase-like Acyl-CoA acyltransferase domain DUF1298 PF06974.13 KXS22517.1 - 1.6e-20 73.5 0.0 3.8e-20 72.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1298) MFS_1 PF07690.16 KXS22519.1 - 1.5e-24 86.6 20.8 1.5e-24 86.6 20.8 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 KXS22519.1 - 3.2e-09 35.9 15.2 1.7e-08 33.4 0.1 3.1 2 1 1 3 3 3 2 MFS/sugar transport protein MFS_1_like PF12832.7 KXS22519.1 - 2.7 6.8 13.9 0.071 12.0 0.6 2.5 1 1 2 3 3 3 0 MFS_1 like family Beta-lactamase PF00144.24 KXS22520.1 - 5.8e-28 98.1 0.8 7.5e-28 97.7 0.8 1.1 1 0 0 1 1 1 1 Beta-lactamase GCR1_C PF12550.8 KXS22520.1 - 0.26 11.6 0.4 0.53 10.7 0.1 1.6 2 0 0 2 2 2 0 Transcriptional activator of glycolytic enzymes p450 PF00067.22 KXS22521.1 - 4e-55 187.4 0.0 5.1e-55 187.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 TFIIS_C PF01096.18 KXS22523.1 - 1.8e-17 62.9 2.2 1.8e-17 62.9 2.2 2.7 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 KXS22523.1 - 2e-07 30.8 8.1 0.00032 20.5 0.3 2.9 2 1 0 2 2 2 2 RNA polymerases M/15 Kd subunit DZR PF12773.7 KXS22523.1 - 3.3e-05 23.8 9.6 0.0024 17.8 0.6 3.1 1 1 0 2 2 2 1 Double zinc ribbon Lar_restr_allev PF14354.6 KXS22523.1 - 0.00018 21.8 5.8 0.15 12.5 0.3 2.8 2 1 0 2 2 2 2 Restriction alleviation protein Lar IBR PF01485.21 KXS22523.1 - 0.0002 21.5 4.6 0.2 11.9 0.1 2.3 2 1 0 2 2 2 2 IBR domain, a half RING-finger domain HypA PF01155.19 KXS22523.1 - 0.0013 18.7 6.3 0.095 12.7 0.2 3.0 2 1 1 3 3 3 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf_UBZ PF18439.1 KXS22523.1 - 0.0034 16.9 8.7 2.8 7.6 0.0 4.1 4 0 0 4 4 4 1 Ubiquitin-Binding Zinc Finger C1_1 PF00130.22 KXS22523.1 - 0.0043 16.9 4.7 0.032 14.1 0.1 2.5 2 1 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) TF_Zn_Ribbon PF08271.12 KXS22523.1 - 0.0076 15.7 14.0 0.22 11.0 2.0 3.6 2 2 1 3 3 3 2 TFIIB zinc-binding zf-H2C2_2 PF13465.6 KXS22523.1 - 0.0098 16.3 8.4 0.18 12.3 0.5 3.6 4 0 0 4 4 3 1 Zinc-finger double domain TackOD1 PF18551.1 KXS22523.1 - 0.013 15.2 4.0 0.99 9.0 0.1 2.2 2 0 0 2 2 2 0 Thaumarchaeal output domain 1 zf-ACC PF17848.1 KXS22523.1 - 0.021 14.9 9.0 2.5 8.3 0.1 4.1 3 1 1 4 4 4 0 Acetyl-coA carboxylase zinc finger domain Baculo_LEF5_C PF11792.8 KXS22523.1 - 0.022 14.4 0.1 0.022 14.4 0.1 2.6 4 0 0 4 4 3 0 Baculoviridae late expression factor 5 C-terminal domain zf-ribbon_3 PF13248.6 KXS22523.1 - 0.024 14.1 12.5 6.2 6.4 0.1 4.2 3 1 1 4 4 4 0 zinc-ribbon domain zf-RING_7 PF02591.15 KXS22523.1 - 0.024 14.8 3.1 3.1 8.0 0.0 3.9 4 0 0 4 4 4 0 C4-type zinc ribbon domain Zn_ribbon_SprT PF17283.2 KXS22523.1 - 0.031 14.2 3.4 3.7 7.5 0.2 2.8 3 0 0 3 3 3 0 SprT-like zinc ribbon domain Zn_Tnp_IS1595 PF12760.7 KXS22523.1 - 0.041 13.8 5.5 0.052 13.5 0.8 2.6 2 1 1 3 3 3 0 Transposase zinc-ribbon domain Zn-ribbon_8 PF09723.10 KXS22523.1 - 0.051 13.7 10.8 4.5 7.5 0.9 3.7 3 1 0 3 3 3 0 Zinc ribbon domain Zn_ribbon_recom PF13408.6 KXS22523.1 - 0.16 12.5 3.5 11 6.7 0.1 3.1 3 0 0 3 3 3 0 Recombinase zinc beta ribbon domain zinc_ribbon_6 PF14599.6 KXS22523.1 - 0.18 11.8 0.1 0.18 11.8 0.1 2.3 2 1 0 3 3 3 0 Zinc-ribbon RPA_interact_C PF14768.6 KXS22523.1 - 0.2 12.3 5.7 2.1 8.9 0.5 2.6 2 1 0 2 2 2 0 Replication protein A interacting C-terminal eIF-5_eIF-2B PF01873.17 KXS22523.1 - 0.26 11.2 6.7 0.87 9.5 1.0 2.2 2 0 0 2 2 2 0 Domain found in IF2B/IF5 zf-C3HC4_3 PF13920.6 KXS22523.1 - 0.28 11.1 3.9 3.7 7.5 0.1 2.9 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_4 PF13717.6 KXS22523.1 - 0.29 11.1 8.3 8.7 6.4 0.2 3.8 4 0 0 4 4 4 0 zinc-ribbon domain zf-C2H2 PF00096.26 KXS22523.1 - 0.32 11.5 11.8 2.3 8.8 1.3 4.3 4 0 0 4 4 4 0 Zinc finger, C2H2 type A2L_zn_ribbon PF08792.10 KXS22523.1 - 0.33 10.7 9.2 1.9 8.3 0.1 3.9 4 0 0 4 4 4 0 A2L zinc ribbon domain C1_2 PF03107.16 KXS22523.1 - 0.43 10.9 8.2 4.8 7.6 0.1 3.0 3 1 0 3 3 3 0 C1 domain DNA_RNApol_7kD PF03604.13 KXS22523.1 - 0.56 9.9 10.3 1.1 9.0 0.5 3.1 3 1 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit zinc_ribbon_2 PF13240.6 KXS22523.1 - 0.61 9.9 14.3 4.8 7.0 0.5 4.1 3 1 0 3 3 3 0 zinc-ribbon domain Ribosomal_S27e PF01667.17 KXS22523.1 - 0.68 9.7 10.5 1.4 8.6 0.0 3.7 2 2 1 3 3 3 0 Ribosomal protein S27 CpXC PF14353.6 KXS22523.1 - 0.95 9.5 8.7 33 4.5 3.3 3.7 3 1 0 3 3 3 0 CpXC protein zinc_ribbon_15 PF17032.5 KXS22523.1 - 1.2 9.9 7.8 5.7 7.8 3.2 3.0 1 1 2 3 3 3 0 zinc-ribbon family Prok-RING_1 PF14446.6 KXS22523.1 - 1.3 9.0 10.7 0.79 9.7 2.5 3.3 3 1 1 4 4 4 0 Prokaryotic RING finger family 1 OrfB_Zn_ribbon PF07282.11 KXS22523.1 - 1.3 9.0 9.3 0.63 10.0 0.4 2.8 2 1 1 3 3 3 0 Putative transposase DNA-binding domain zf-TFIIB PF13453.6 KXS22523.1 - 1.7 8.0 8.6 0.15 11.4 0.8 2.3 2 0 0 2 2 2 0 Transcription factor zinc-finger zf-AN1 PF01428.16 KXS22523.1 - 2.2 8.5 9.4 10 6.4 0.6 3.3 3 1 1 4 4 4 0 AN1-like Zinc finger Nudix_N_2 PF14803.6 KXS22523.1 - 2.6 8.0 10.9 7.8 6.5 0.0 3.9 3 1 1 4 4 4 0 Nudix N-terminal zf_C2H2_10 PF18414.1 KXS22523.1 - 2.6 7.7 4.8 19 4.9 0.2 2.4 2 0 0 2 2 2 0 C2H2 type zinc-finger PHD PF00628.29 KXS22523.1 - 2.8 7.9 9.7 15 5.6 2.7 3.6 3 1 1 4 4 4 0 PHD-finger Ogr_Delta PF04606.12 KXS22523.1 - 3.2 7.8 7.7 0.47 10.5 0.9 2.6 3 0 0 3 3 2 0 Ogr/Delta-like zinc finger zf-Mss51 PF13824.6 KXS22523.1 - 4.8 7.4 11.0 2.2e+03 -1.2 11.0 3.5 1 1 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-B_box PF00643.24 KXS22523.1 - 5.8 7.2 8.7 27 5.0 0.1 3.6 4 0 0 4 4 4 0 B-box zinc finger NOB1_Zn_bind PF08772.11 KXS22523.1 - 8.8 6.6 8.9 28 5.0 1.1 3.2 2 2 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like PhyH PF05721.13 KXS22524.1 - 1.3e-24 87.7 0.0 1.7e-24 87.3 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Ran_BP1 PF00638.18 KXS22525.1 - 8.7e-49 164.8 0.4 1.3e-48 164.3 0.4 1.2 1 0 0 1 1 1 1 RanBP1 domain DUF1681 PF07933.14 KXS22525.1 - 0.00042 20.1 0.3 0.00056 19.6 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) Nup_retrotrp_bd PF10599.9 KXS22525.1 - 0.43 11.3 7.6 1.1 10.0 7.6 1.6 1 0 0 1 1 1 0 Retro-transposon transporting motif Rab5-bind PF09311.11 KXS22526.1 - 0.005 16.3 0.8 0.012 15.1 0.9 1.6 1 1 0 1 1 1 1 Rabaptin-like protein Lebercilin PF15619.6 KXS22526.1 - 0.0079 15.9 0.3 0.47 10.1 0.1 2.4 2 0 0 2 2 2 1 Ciliary protein causing Leber congenital amaurosis disease Baculo_PEP_C PF04513.12 KXS22526.1 - 0.061 13.4 0.2 10 6.2 0.1 2.3 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus TelA PF05816.11 KXS22526.1 - 0.073 12.1 0.1 0.14 11.2 0.1 1.6 1 0 0 1 1 1 0 Toxic anion resistance protein (TelA) Apolipoprotein PF01442.18 KXS22526.1 - 0.075 12.9 1.7 0.21 11.4 1.7 1.7 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Myosin_tail_1 PF01576.19 KXS22526.1 - 0.098 10.5 0.2 0.14 10.0 0.2 1.2 1 0 0 1 1 1 0 Myosin tail DUF4618 PF15397.6 KXS22526.1 - 0.15 11.4 1.1 0.34 10.3 0.0 2.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4618) NPV_P10 PF05531.12 KXS22526.1 - 0.17 12.4 1.4 33 5.0 0.3 3.2 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein TolA_bind_tri PF16331.5 KXS22526.1 - 0.31 11.1 5.7 9.1 6.4 0.1 3.8 3 1 1 4 4 4 0 TolA binding protein trimerisation Spectrin PF00435.21 KXS22526.1 - 0.33 11.4 1.1 1.1 9.7 0.0 2.5 4 0 0 4 4 2 0 Spectrin repeat Synthase_beta PF11421.8 KXS22526.1 - 3.9 8.2 6.3 1 10.1 1.7 2.4 2 0 0 2 2 2 0 ATP synthase F1 beta subunit HalX PF08663.10 KXS22526.1 - 5.5 7.4 8.2 1.6 9.1 0.2 3.4 2 1 1 3 3 3 0 HalX domain DUF1664 PF07889.12 KXS22527.1 - 0.0052 16.8 6.1 0.12 12.4 1.2 3.4 1 1 2 3 3 3 2 Protein of unknown function (DUF1664) DUF948 PF06103.11 KXS22527.1 - 0.018 15.3 1.6 1.6 9.0 0.2 2.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) FlaC_arch PF05377.11 KXS22527.1 - 0.03 14.7 1.0 7.4 7.1 0.0 3.2 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Prominin PF05478.11 KXS22527.1 - 0.15 10.0 4.6 0.25 9.3 4.6 1.2 1 0 0 1 1 1 0 Prominin O-antigen_lig PF13425.6 KXS22527.1 - 0.3 9.8 0.4 0.6 8.8 0.4 1.4 1 0 0 1 1 1 0 O-antigen ligase like membrane protein DUF4559 PF15112.6 KXS22527.1 - 0.48 10.1 8.0 0.85 9.2 8.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) DUF4618 PF15397.6 KXS22527.1 - 0.94 8.8 10.6 1.8 7.9 2.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) DHR10 PF18595.1 KXS22527.1 - 0.99 9.5 11.8 1.3 9.1 8.4 2.6 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain DUF3584 PF12128.8 KXS22527.1 - 1.1 6.7 22.4 0.63 7.5 6.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) ApoO PF09769.9 KXS22527.1 - 1.4 8.9 4.1 7.5 6.5 1.4 2.8 1 1 1 2 2 2 0 Apolipoprotein O DUF1664 PF07889.12 KXS22528.1 - 0.0046 17.0 6.1 0.12 12.4 1.0 3.4 1 1 2 3 3 3 2 Protein of unknown function (DUF1664) FlaC_arch PF05377.11 KXS22528.1 - 0.027 14.9 1.0 7.1 7.1 0.0 3.2 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) DUF948 PF06103.11 KXS22528.1 - 0.072 13.4 3.7 1.6 9.1 0.2 2.8 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Prominin PF05478.11 KXS22528.1 - 0.14 10.1 4.6 0.24 9.3 4.6 1.2 1 0 0 1 1 1 0 Prominin O-antigen_lig PF13425.6 KXS22528.1 - 0.28 9.9 0.4 0.57 8.9 0.4 1.4 1 0 0 1 1 1 0 O-antigen ligase like membrane protein DUF4559 PF15112.6 KXS22528.1 - 0.45 10.1 8.0 0.81 9.3 8.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) DUF4618 PF15397.6 KXS22528.1 - 0.85 9.0 10.6 5.9 6.2 6.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) DHR10 PF18595.1 KXS22528.1 - 0.95 9.5 11.9 1.3 9.1 8.4 2.7 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain DUF3584 PF12128.8 KXS22528.1 - 1 6.8 22.4 0.6 7.6 6.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) ApoO PF09769.9 KXS22528.1 - 1 9.3 3.9 6.3 6.8 1.2 2.8 1 1 1 2 2 2 0 Apolipoprotein O Guanylate_cyc PF00211.20 KXS22529.1 - 2e-50 170.9 0.0 5.8e-50 169.5 0.0 1.6 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain HNOBA PF07701.14 KXS22529.1 - 0.011 15.2 0.2 0.016 14.6 0.2 1.2 1 0 0 1 1 1 0 Heme NO binding associated Guanylate_cyc PF00211.20 KXS22530.1 - 2.1e-49 167.6 0.1 5.3e-49 166.3 0.0 1.6 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain HNOBA PF07701.14 KXS22530.1 - 0.0016 17.9 0.4 0.0026 17.2 0.4 1.3 1 0 0 1 1 1 1 Heme NO binding associated HAUS-augmin3 PF14932.6 KXS22530.1 - 0.079 12.5 0.5 0.11 12.1 0.5 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 ING PF12998.7 KXS22530.1 - 0.14 12.7 0.1 0.27 11.9 0.1 1.5 1 0 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding DLH PF01738.18 KXS22531.1 - 2.2e-23 83.0 0.0 3e-23 82.5 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S15 PF02129.18 KXS22531.1 - 0.024 14.3 0.1 0.071 12.7 0.0 1.7 1 1 1 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) BAAT_C PF08840.11 KXS22531.1 - 0.026 14.4 0.0 0.038 13.9 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_6 PF12697.7 KXS22531.1 - 0.033 14.8 0.6 0.046 14.3 0.6 1.3 1 1 0 1 1 1 0 Alpha/beta hydrolase family MFS_1 PF07690.16 KXS22532.1 - 8e-26 90.8 33.6 1.2e-25 90.2 33.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Porphobil_deam PF01379.20 KXS22533.1 - 7.9e-74 247.6 0.0 1.4e-73 246.8 0.0 1.4 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 KXS22533.1 - 2.1e-10 40.9 0.1 1.8e-09 37.9 0.1 2.4 1 1 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain Ist1 PF03398.14 KXS22534.1 - 1.2e-57 194.4 2.8 1.5e-57 194.1 2.8 1.0 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway p450 PF00067.22 KXS22535.1 - 1.3e-19 70.3 0.0 1.4e-19 70.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KXS22538.1 - 8e-32 110.6 0.0 3.7e-31 108.4 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 TPR_2 PF07719.17 KXS22539.1 - 1.2e-06 28.1 3.8 0.0051 16.8 0.0 5.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.6 KXS22539.1 - 3.1e-06 27.5 15.6 0.13 13.2 0.3 5.6 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 KXS22539.1 - 6.5e-06 26.6 7.6 0.035 14.6 0.4 3.8 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 KXS22539.1 - 6e-05 23.1 0.1 0.35 11.3 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KXS22539.1 - 9e-05 22.4 0.0 0.27 11.6 0.0 4.3 5 0 0 5 5 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KXS22539.1 - 0.00024 21.2 0.0 1.2 9.4 0.0 3.3 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 KXS22539.1 - 0.0031 17.3 0.0 1.3 9.0 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 KXS22539.1 - 0.032 13.9 0.0 1.9 8.2 0.0 2.8 3 0 0 3 3 3 0 TPR repeat TPR_4 PF07721.14 KXS22539.1 - 0.069 13.8 0.3 0.069 13.8 0.3 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 KXS22539.1 - 0.071 13.4 3.1 4.2 7.7 0.0 3.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 KXS22539.1 - 0.28 11.3 7.2 0.2 11.8 0.6 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 KXS22539.1 - 0.45 11.2 13.1 0.57 10.9 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat NmrA PF05368.13 KXS22540.1 - 2.2e-14 53.6 0.1 3e-14 53.1 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXS22540.1 - 5.2e-10 39.5 0.0 1.1e-09 38.5 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding Shikimate_DH PF01488.20 KXS22540.1 - 0.0086 16.1 0.0 0.019 15.0 0.0 1.6 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Macro_2 PF14519.6 KXS22540.1 - 0.16 11.3 0.0 0.53 9.6 0.0 1.8 2 0 0 2 2 2 0 Macro-like domain Rhomboid PF01694.22 KXS22541.1 - 5.4e-21 75.2 13.9 5.4e-21 75.2 13.9 1.8 2 0 0 2 2 2 1 Rhomboid family DUF5325 PF17259.2 KXS22541.1 - 0.46 10.4 4.1 0.39 10.6 0.6 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5325) Asn_synthase PF00733.21 KXS22542.1 - 6e-15 55.8 0.3 2.6e-05 24.0 0.0 3.2 2 1 1 3 3 3 3 Asparagine synthase GATase_7 PF13537.6 KXS22542.1 - 9.3e-09 35.3 0.0 4.4e-08 33.1 0.0 2.0 1 1 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 KXS22542.1 - 0.00059 20.1 0.0 0.0013 18.9 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain MFS_1_like PF12832.7 KXS22543.1 - 7.2e-47 160.1 16.7 9.7e-47 159.6 16.7 1.1 1 0 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 KXS22543.1 - 4.6e-21 75.1 32.0 1.7e-13 50.2 12.6 3.0 1 1 2 3 3 3 3 Major Facilitator Superfamily Nuc_H_symport PF03825.16 KXS22543.1 - 8.1e-07 28.4 9.3 8.1e-07 28.4 9.3 1.6 2 0 0 2 2 2 1 Nucleoside H+ symporter DUF4501 PF14946.6 KXS22543.1 - 0.22 11.6 0.2 0.42 10.7 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4501) AMP-binding PF00501.28 KXS22544.1 - 8.8e-14 50.9 0.0 1.4e-13 50.3 0.0 1.2 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding PF00501.28 KXS22545.1 - 0.017 13.7 0.0 0.018 13.6 0.0 1.1 1 0 0 1 1 1 0 AMP-binding enzyme Det1 PF09737.9 KXS22546.1 - 1.7e-73 248.1 0.0 3.2e-48 164.8 0.0 2.1 2 0 0 2 2 2 2 De-etiolated protein 1 Det1 Ank_5 PF13857.6 KXS22547.1 - 0.0013 19.0 0.0 0.04 14.2 0.0 3.1 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXS22547.1 - 0.0015 19.1 0.0 0.019 15.6 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) SH3_2 PF07653.17 KXS22547.1 - 0.0056 16.3 0.0 0.015 15.0 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain Ank_4 PF13637.6 KXS22547.1 - 0.012 16.1 0.0 8.6 7.1 0.0 3.5 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXS22547.1 - 0.048 14.2 0.0 0.62 10.8 0.0 2.6 2 0 0 2 2 2 0 Ankyrin repeat KASH_CCD PF14662.6 KXS22547.1 - 0.065 13.1 0.8 0.14 12.0 0.8 1.5 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH BRE1 PF08647.11 KXS22547.1 - 0.21 11.7 0.0 0.39 10.8 0.0 1.4 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase SNF PF00209.18 KXS22548.1 - 2.6e-83 280.5 30.0 1.2e-80 271.8 30.0 2.1 1 1 0 1 1 1 1 Sodium:neurotransmitter symporter family Lipase_3 PF01764.25 KXS22549.1 - 7.3e-18 64.8 0.0 1.4e-17 63.9 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 KXS22549.1 - 0.022 14.0 0.0 0.04 13.2 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 adh_short PF00106.25 KXS22553.1 - 2.3e-17 63.1 0.0 1.1e-15 57.6 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXS22553.1 - 4.4e-14 52.6 0.0 1.2e-13 51.2 0.0 1.6 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXS22553.1 - 0.00015 21.7 0.2 0.00084 19.3 0.2 1.9 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KXS22553.1 - 0.0092 15.5 0.1 0.015 14.8 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family HEM4 PF02602.15 KXS22553.1 - 0.019 14.3 0.2 0.03 13.7 0.2 1.3 1 0 0 1 1 1 0 Uroporphyrinogen-III synthase HemD Meckelin PF09773.9 KXS22554.1 - 1.4e-133 446.8 0.0 1.8e-133 446.5 0.0 1.1 1 0 0 1 1 1 1 Meckelin (Transmembrane protein 67) Ephrin_rec_like PF07699.13 KXS22554.1 - 0.71 9.7 10.8 1.1 9.0 5.5 2.6 2 0 0 2 2 2 0 Putative ephrin-receptor like cEGF PF12662.7 KXS22554.1 - 8.8 6.4 9.9 2.7 8.0 2.9 2.6 2 0 0 2 2 2 0 Complement Clr-like EGF-like WD40 PF00400.32 KXS22555.1 - 6.1e-10 39.5 1.7 0.0033 18.2 0.0 5.0 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXS22555.1 - 0.0033 17.7 0.1 1.8 8.9 0.0 4.4 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain TMP_2 PF06791.13 KXS22555.1 - 0.03 14.0 0.5 2.1 8.0 0.0 2.5 2 0 0 2 2 2 0 Prophage tail length tape measure protein Kelch_5 PF13854.6 KXS22556.1 - 0.00013 21.8 1.9 0.012 15.5 1.4 3.3 2 0 0 2 2 2 1 Kelch motif SH3_9 PF14604.6 KXS22556.1 - 0.00085 19.1 0.0 0.0018 18.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Kelch_2 PF07646.15 KXS22556.1 - 0.031 14.2 0.8 5.2 7.2 0.4 3.4 2 0 0 2 2 2 0 Kelch motif Kelch_6 PF13964.6 KXS22556.1 - 0.034 14.4 7.6 0.64 10.4 1.0 4.4 4 0 0 4 4 4 0 Kelch motif SH3_1 PF00018.28 KXS22556.1 - 0.045 13.4 0.0 0.12 12.0 0.0 1.7 1 0 0 1 1 1 0 SH3 domain SseC PF04888.12 KXS22556.1 - 0.089 12.4 0.7 0.18 11.4 0.7 1.4 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Kelch_1 PF01344.25 KXS22556.1 - 0.58 9.8 5.8 0.31 10.7 1.8 2.6 2 0 0 2 2 2 0 Kelch motif ZZ PF00569.17 KXS22557.1 - 2.5e-08 33.6 2.5 4.2e-08 32.9 2.5 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type adh_short PF00106.25 KXS22558.1 - 3.7e-32 111.4 0.0 4.6e-32 111.1 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXS22558.1 - 1.7e-23 83.4 0.0 2.2e-23 83.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXS22558.1 - 7.7e-10 39.0 0.0 9.9e-10 38.6 0.0 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KXS22558.1 - 9.8e-09 35.0 0.0 4.8e-06 26.2 0.0 2.3 2 0 0 2 2 2 2 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.6 KXS22558.1 - 0.00014 21.8 0.0 0.00019 21.4 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KXS22558.1 - 0.00016 21.2 0.0 0.0003 20.3 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KXS22558.1 - 0.081 13.2 0.1 0.12 12.6 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain RmlD_sub_bind PF04321.17 KXS22558.1 - 0.11 11.6 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 KXS22558.1 - 0.21 10.9 0.2 0.42 10.0 0.2 1.7 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase TPR_2 PF07719.17 KXS22559.1 - 5.6e-11 41.7 0.6 1.7e-05 24.6 0.1 5.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 KXS22559.1 - 1.9e-06 27.4 0.1 0.00026 20.7 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KXS22559.1 - 0.0002 21.9 1.1 0.26 12.2 0.0 5.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_9 PF13371.6 KXS22559.1 - 0.0003 20.9 1.7 7.9 6.7 0.0 5.1 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 KXS22559.1 - 0.0031 17.6 1.1 0.035 14.3 0.1 3.3 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 KXS22559.1 - 0.05 14.3 1.4 7.1 7.4 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 KXS22559.1 - 0.058 13.1 0.0 0.63 9.8 0.0 2.8 2 0 0 2 2 2 0 TPR repeat TPR_12 PF13424.6 KXS22559.1 - 0.07 13.4 2.1 8.7 6.7 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 KXS22559.1 - 0.18 12.5 2.8 3.8 8.4 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat YycC PF14174.6 KXS22559.1 - 0.18 11.7 0.2 2 8.3 0.3 2.4 2 0 0 2 2 2 0 YycC-like protein Bestrophin PF01062.21 KXS22560.1 - 2.7e-22 79.5 0.0 3.7e-22 79.1 0.0 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel DUF5353 PF17304.2 KXS22560.1 - 0.31 10.8 1.3 0.58 9.9 0.1 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5353) C1_1 PF00130.22 KXS22561.1 - 7.1e-14 51.4 19.1 5.7e-07 29.3 6.8 2.2 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Rtf2 PF04641.12 KXS22561.1 - 0.41 10.0 9.7 0.83 9.0 9.7 1.5 1 0 0 1 1 1 0 Rtf2 RING-finger C1_2 PF03107.16 KXS22561.1 - 0.96 9.8 12.2 0.14 12.5 1.5 2.3 2 0 0 2 2 2 0 C1 domain Prok-RING_1 PF14446.6 KXS22561.1 - 2 8.4 20.2 0.09 12.7 6.0 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 DNA_RNApol_7kD PF03604.13 KXS22561.1 - 2.2 8.0 8.8 0.15 11.8 1.1 2.6 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit PQ-loop PF04193.14 KXS22563.1 - 1e-29 102.0 5.0 3.2e-15 55.6 2.2 2.9 4 0 0 4 4 4 2 PQ loop repeat 4HBT_3 PF13622.6 KXS22564.1 - 2.1e-29 103.5 1.0 2.8e-29 103.1 1.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily PGBA_C PF15437.6 KXS22564.1 - 0.0054 17.1 8.8 0.01 16.1 8.8 1.4 1 0 0 1 1 1 1 Plasminogen-binding protein pgbA C-terminal 4HBT PF03061.22 KXS22564.1 - 0.049 14.0 0.1 0.13 12.6 0.1 1.8 1 0 0 1 1 1 0 Thioesterase superfamily Copine PF07002.16 KXS22568.1 - 1.6e-65 220.6 0.0 2.2e-65 220.2 0.0 1.2 1 0 0 1 1 1 1 Copine C2 PF00168.30 KXS22568.1 - 5.6e-23 81.2 0.0 2.4e-10 40.6 0.0 2.6 2 1 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.9 KXS22568.1 - 0.025 14.7 0.0 0.048 13.8 0.0 1.4 1 0 0 1 1 1 0 vWA found in TerF C terminus RNA_ligase PF09414.10 KXS22569.1 - 8.5e-10 39.2 0.0 1.4e-09 38.5 0.0 1.3 1 0 0 1 1 1 1 RNA ligase Lip_prot_lig_C PF10437.9 KXS22569.1 - 0.086 12.8 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Bacterial lipoate protein ligase C-terminus DAO PF01266.24 KXS22570.1 - 2.6e-42 145.7 0.8 3.1e-42 145.4 0.8 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXS22570.1 - 1.1e-05 25.6 1.5 3.6e-05 23.9 1.5 2.0 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KXS22570.1 - 1.3e-05 25.3 0.2 0.00012 22.1 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KXS22570.1 - 0.0011 18.2 0.0 0.12 11.6 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXS22570.1 - 0.0018 17.5 0.2 0.0032 16.8 0.2 1.3 1 0 0 1 1 1 1 Thi4 family K_oxygenase PF13434.6 KXS22570.1 - 0.037 13.2 0.0 0.36 9.9 0.0 2.0 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.12 KXS22570.1 - 0.14 11.2 0.2 0.25 10.4 0.2 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein AIMP2_LysRS_bd PF16780.5 KXS22573.1 - 0.027 14.2 0.1 0.11 12.2 0.0 2.1 2 0 0 2 2 2 0 AIMP2 lysyl-tRNA synthetase binding domain AAA PF00004.29 KXS22574.1 - 1e-19 71.3 0.0 1.6e-12 48.0 0.0 3.3 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KXS22574.1 - 0.0021 18.5 0.0 0.0052 17.2 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 KXS22574.1 - 0.0039 16.5 0.0 0.015 14.6 0.0 1.8 2 0 0 2 2 2 1 Zeta toxin AAA_5 PF07728.14 KXS22574.1 - 0.016 15.2 0.2 0.25 11.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) T2SSE PF00437.20 KXS22574.1 - 0.14 11.1 0.0 0.24 10.4 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein RuvB_N PF05496.12 KXS22574.1 - 0.16 11.7 0.0 0.32 10.7 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Lipase_GDSL PF00657.22 KXS22576.1 - 5e-06 26.6 0.0 9e-06 25.8 0.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 KXS22576.1 - 1.3e-05 25.7 2.8 0.00017 22.0 2.8 2.2 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Abhydrolase_6 PF12697.7 KXS22577.1 - 1.3e-13 52.1 0.4 1.9e-13 51.6 0.4 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXS22577.1 - 1.7e-12 47.6 0.2 1.2e-11 44.8 0.1 1.9 1 1 1 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXS22577.1 - 2.1e-11 43.6 0.1 1.4e-08 34.3 0.0 2.3 1 1 1 2 2 2 2 Serine aminopeptidase, S33 DUF915 PF06028.11 KXS22577.1 - 0.03 13.6 0.0 2.7 7.3 0.0 2.9 3 0 0 3 3 3 0 Alpha/beta hydrolase of unknown function (DUF915) PGAP1 PF07819.13 KXS22577.1 - 0.041 13.6 0.1 1.5 8.5 0.0 2.3 2 0 0 2 2 2 0 PGAP1-like protein Thioesterase PF00975.20 KXS22577.1 - 0.1 12.7 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_6 PF12697.7 KXS22579.1 - 5.8e-16 59.8 1.5 5.8e-16 59.8 1.5 2.0 2 1 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXS22579.1 - 5e-15 55.4 0.1 1e-13 51.1 0.0 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KXS22579.1 - 2.1e-13 50.5 0.4 6.9e-13 48.8 0.2 1.8 1 1 1 2 2 2 1 alpha/beta hydrolase fold DUF1057 PF06342.12 KXS22579.1 - 0.00091 18.3 0.0 0.0015 17.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) DLH PF01738.18 KXS22579.1 - 0.17 11.4 0.0 0.32 10.5 0.0 1.5 1 0 0 1 1 1 0 Dienelactone hydrolase family PAF-AH_p_II PF03403.13 KXS22579.1 - 0.18 10.3 0.1 0.72 8.3 0.0 1.9 3 0 0 3 3 3 0 Platelet-activating factor acetylhydrolase, isoform II DUF915 PF06028.11 KXS22579.1 - 0.18 11.1 0.0 10 5.4 0.0 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) LCAT PF02450.15 KXS22579.1 - 0.21 10.7 0.0 0.31 10.2 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase F-box-like PF12937.7 KXS22580.1 - 0.0023 17.8 3.8 0.0057 16.5 3.8 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXS22580.1 - 0.0038 17.1 3.0 0.01 15.7 3.0 1.7 1 0 0 1 1 1 1 F-box domain FGGY_C PF02782.16 KXS22581.1 - 3.1e-33 115.2 0.1 4.4e-33 114.7 0.1 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 KXS22581.1 - 3.6e-11 43.1 3.4 5.3e-11 42.5 1.4 2.2 2 1 0 2 2 2 1 FGGY family of carbohydrate kinases, N-terminal domain MFS_1 PF07690.16 KXS22582.1 - 9.6e-45 153.0 57.9 6.5e-44 150.3 57.9 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KXS22582.1 - 6.4e-13 48.0 25.7 8.9e-13 47.5 25.7 1.2 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KXS22582.1 - 7.3e-10 38.3 16.4 7.3e-10 38.3 16.4 3.0 2 1 1 3 3 3 1 Sugar (and other) transporter Pox_A14 PF05767.12 KXS22582.1 - 0.01 15.9 2.3 0.01 15.9 2.3 3.2 3 1 1 4 4 4 0 Poxvirus virion envelope protein A14 DUF155 PF02582.14 KXS22583.1 - 5.3e-49 166.7 0.0 7.4e-49 166.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 MG2 PF01835.19 KXS22584.1 - 0.095 13.2 0.0 0.16 12.4 0.0 1.4 1 0 0 1 1 1 0 MG2 domain Reeler PF02014.16 KXS22585.1 - 2.9e-06 28.1 0.0 4.6e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Reeler domain Ferritin_2 PF13668.6 KXS22586.1 - 0.017 15.3 0.0 0.29 11.3 0.0 2.3 2 0 0 2 2 2 0 Ferritin-like domain T4SS PF07996.11 KXS22586.1 - 0.047 14.1 0.1 0.16 12.4 0.0 1.9 2 0 0 2 2 2 0 Type IV secretion system proteins V-SNARE_C PF12352.8 KXS22587.1 - 0.0027 17.9 1.2 1.4 9.3 0.1 2.5 2 0 0 2 2 2 2 Snare region anchored in the vesicle membrane C-terminus Synaptobrevin PF00957.21 KXS22587.1 - 0.073 12.9 1.4 0.12 12.2 0.1 2.0 2 1 1 3 3 3 0 Synaptobrevin NPV_P10 PF05531.12 KXS22587.1 - 0.1 13.1 0.4 34 5.0 0.1 3.1 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein COG2 PF06148.11 KXS22587.1 - 0.2 11.8 1.4 5.3 7.1 0.3 2.4 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4715 PF15835.5 KXS22587.1 - 1.7 8.7 4.6 0.53 10.4 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4715) FoP_duplication PF13865.6 KXS22587.1 - 3.2 8.4 21.0 0.5 11.0 8.7 3.1 2 2 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 HTH_Crp_2 PF13545.6 KXS22588.1 - 0.23 11.5 0.0 0.4 10.7 0.0 1.4 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain ATP_transf PF09830.9 KXS22589.1 - 1.3e-12 47.7 0.0 2e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 ATP adenylyltransferase DUF4922 PF16269.5 KXS22589.1 - 0.0093 15.7 0.1 1.9 8.2 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4922) DUF4931 PF16285.5 KXS22589.1 - 0.041 13.2 0.2 0.081 12.2 0.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4931) Pkinase PF00069.25 KXS22590.1 - 7.6e-63 212.3 0.0 1.4e-62 211.4 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS22590.1 - 2e-32 112.5 0.0 3.4e-32 111.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.22 KXS22590.1 - 3e-16 59.0 22.4 8.3e-09 35.2 11.0 2.3 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.24 KXS22590.1 - 1.2e-12 48.4 1.9 3.5e-12 46.8 1.9 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain HR1 PF02185.16 KXS22590.1 - 4.8e-12 45.8 8.6 5.6e-08 32.8 5.8 4.8 4 2 1 5 5 5 2 Hr1 repeat C2 PF00168.30 KXS22590.1 - 6.2e-05 23.2 0.0 0.00011 22.4 0.0 1.4 1 0 0 1 1 1 1 C2 domain C1_2 PF03107.16 KXS22590.1 - 0.00013 22.2 18.2 0.0017 18.7 6.8 2.3 2 0 0 2 2 2 2 C1 domain DUF5401 PF17380.2 KXS22590.1 - 0.28 9.2 65.9 0.42 8.6 65.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) GST_N_4 PF17172.4 KXS22591.1 - 1.6e-15 57.7 0.0 3.1e-15 56.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 KXS22591.1 - 3.9e-13 49.0 0.0 8e-13 48.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KXS22591.1 - 1.3e-05 25.1 0.1 4.7e-05 23.3 0.1 2.0 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 KXS22591.1 - 0.00016 22.0 0.0 0.00027 21.2 0.0 1.4 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C PF00043.25 KXS22591.1 - 0.11 12.7 0.0 0.45 10.8 0.0 2.0 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Chytridiomycota/Gonapodya_prolifera_JEL478-Ganpr1/GCA_001574975.1_Ganpr1_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Chytridiomycota/Gonapodya_prolifera_JEL478-Ganpr1/GCA_001574975.1_Ganpr1_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Chytridiomycota/Gonapodya_prolifera_JEL478-Ganpr1/GCA_001574975.1_Ganpr1_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Chytridiomycota/Gonapodya_prolifera_JEL478-Ganpr1/GCA_001574975.1_Ganpr1_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Mon Mar 25 18:02:55 2019 # [ok]