# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- UQ_con PF00179.26 EAQ82853.1 - 1.7e-35 121.7 0.0 1.9e-35 121.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EAQ82853.1 - 0.15 11.8 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B TPR_1 PF00515.28 EAQ82854.1 - 0.034 14.0 0.3 0.074 12.9 0.3 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_7 PF13176.6 EAQ82854.1 - 0.1 12.7 0.1 0.45 10.7 0.1 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 EAQ82854.1 - 0.14 12.3 0.3 0.34 11.1 0.3 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat Sel1 PF08238.12 EAQ82854.1 - 0.16 12.7 0.1 0.43 11.3 0.1 1.8 1 0 0 1 1 1 0 Sel1 repeat RVT_2 PF07727.14 EAQ82858.1 - 4.5e-11 42.8 0.0 8.4e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 EAQ82858.1 - 2.7e-08 34.0 0.1 1.4e-07 31.7 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.6 EAQ82858.1 - 1.4e-05 24.9 0.4 3.4e-05 23.6 0.4 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain zf-RVT PF13966.6 EAQ82859.1 - 0.012 16.3 0.1 0.055 14.2 0.0 2.1 2 1 0 2 2 2 0 zinc-binding in reverse transcriptase RT_RNaseH PF17917.1 EAQ82860.1 - 5.6e-37 126.2 0.1 1.3e-36 125.1 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 EAQ82860.1 - 2e-34 117.6 0.0 4.6e-34 116.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 EAQ82860.1 - 5.7e-26 91.4 0.0 1.7e-25 89.9 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 EAQ82860.1 - 7.4e-14 51.6 0.0 2.3e-13 50.1 0.0 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain Chromo PF00385.24 EAQ82860.1 - 4.7e-08 32.8 2.5 1.2e-07 31.5 2.5 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 EAQ82860.1 - 6.8e-05 23.0 0.1 0.00024 21.3 0.0 2.0 2 0 0 2 2 1 1 Integrase core domain Asp_protease_2 PF13650.6 EAQ82860.1 - 0.00018 22.0 0.0 0.0004 21.0 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease AAA_13 PF13166.6 EAQ82860.1 - 0.0031 16.2 2.1 0.0031 16.2 2.1 1.7 2 0 0 2 2 2 1 AAA domain BRE1 PF08647.11 EAQ82860.1 - 0.0069 16.4 3.6 0.016 15.3 3.6 1.6 1 0 0 1 1 1 1 BRE1 E3 ubiquitin ligase zf-H2C2 PF09337.10 EAQ82860.1 - 0.018 15.2 0.0 0.059 13.6 0.0 1.9 1 0 0 1 1 1 0 H2C2 zinc finger Taxilin PF09728.9 EAQ82860.1 - 0.036 13.2 0.2 0.17 11.1 0.2 2.0 1 1 0 1 1 1 0 Myosin-like coiled-coil protein DUF5082 PF16888.5 EAQ82860.1 - 0.057 13.7 2.6 0.47 10.7 1.1 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) Retrotrans_gag PF03732.17 EAQ82860.1 - 0.065 13.5 0.2 0.065 13.5 0.2 3.2 3 0 0 3 3 2 0 Retrotransposon gag protein HAP1_N PF04849.13 EAQ82860.1 - 0.069 12.3 7.2 0.12 11.5 7.2 1.3 1 0 0 1 1 1 0 HAP1 N-terminal conserved region Vps54_N PF10475.9 EAQ82860.1 - 0.14 11.4 1.6 0.21 10.9 0.3 1.8 2 0 0 2 2 2 0 Vacuolar-sorting protein 54, of GARP complex Spc7 PF08317.11 EAQ82860.1 - 0.16 10.8 5.0 0.39 9.6 5.0 1.6 1 0 0 1 1 1 0 Spc7 kinetochore protein UPF0242 PF06785.11 EAQ82860.1 - 0.18 11.9 1.7 0.52 10.4 1.7 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DivIC PF04977.15 EAQ82860.1 - 0.18 11.6 1.0 0.51 10.1 0.1 2.2 1 1 1 2 2 2 0 Septum formation initiator ATG16 PF08614.11 EAQ82860.1 - 0.26 11.5 11.3 0.57 10.4 11.3 1.5 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) FAM76 PF16046.5 EAQ82860.1 - 0.38 10.1 2.3 0.71 9.2 2.3 1.3 1 0 0 1 1 1 0 FAM76 protein IN_DBD_C PF00552.21 EAQ82860.1 - 0.47 9.8 2.5 0.41 10.0 0.1 2.1 2 0 0 2 2 2 0 Integrase DNA binding domain DUF4407 PF14362.6 EAQ82860.1 - 1.5 8.1 4.6 3.1 7.1 4.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RVT_1 PF00078.27 EAQ82861.1 - 1.5e-13 50.8 0.0 2.6e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 EAQ82861.1 - 0.075 13.8 0.0 0.33 11.7 0.0 2.1 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase RVT_1 PF00078.27 EAQ82862.1 - 3.1e-38 131.5 0.1 2.3e-37 128.7 0.0 2.3 3 0 0 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 EAQ82862.1 - 0.0072 16.4 2.5 0.0072 16.4 2.5 2.3 2 0 0 2 2 1 1 Zinc knuckle CASP_C PF08172.12 EAQ82862.1 - 0.014 14.7 1.9 0.049 13.0 1.9 1.9 1 0 0 1 1 1 0 CASP C terminal Herpes_UL6 PF01763.16 EAQ82862.1 - 0.022 13.3 1.7 0.039 12.5 1.7 1.3 1 0 0 1 1 1 0 Herpesvirus UL6 like SlyX PF04102.12 EAQ82862.1 - 0.045 14.4 7.4 0.2 12.3 7.2 2.3 1 1 0 1 1 1 0 SlyX DUF948 PF06103.11 EAQ82862.1 - 0.048 13.9 0.6 0.2 11.9 0.6 2.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Apolipoprotein PF01442.18 EAQ82862.1 - 0.17 11.8 7.7 0.66 9.8 3.2 2.7 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain FAM76 PF16046.5 EAQ82862.1 - 0.79 9.0 4.8 2.8 7.2 1.0 2.5 2 0 0 2 2 2 0 FAM76 protein Phage_Mu_Gam PF07352.12 EAQ82862.1 - 0.98 9.3 3.2 3.4 7.6 2.0 2.6 3 0 0 3 3 3 0 Bacteriophage Mu Gam like protein ADIP PF11559.8 EAQ82862.1 - 1.2 9.2 10.8 0.16 12.1 5.7 2.0 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding TEX13 PF15186.6 EAQ82862.1 - 1.8 8.2 6.1 7.6 6.2 5.5 2.4 2 0 0 2 2 2 0 Testis-expressed sequence 13 protein family Cnn_1N PF07989.11 EAQ82862.1 - 8.1 6.7 7.7 2.3 8.4 2.2 2.5 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 RVT_1 PF00078.27 EAQ82871.1 - 1.3e-37 129.5 0.0 6.4e-37 127.2 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 EAQ82871.1 - 3.8e-26 91.3 0.0 1.4e-25 89.4 0.0 2.1 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 EAQ82871.1 - 0.00022 20.9 0.2 0.00051 19.6 0.2 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-CCHC PF00098.23 EAQ82871.1 - 0.0028 17.7 1.7 0.0028 17.7 1.7 2.6 2 0 0 2 2 1 1 Zinc knuckle SlyX PF04102.12 EAQ82871.1 - 0.0059 17.2 5.6 0.082 13.5 5.6 2.9 1 1 0 1 1 1 1 SlyX USP8_interact PF08941.10 EAQ82871.1 - 0.071 12.9 0.1 0.21 11.4 0.1 1.8 1 0 0 1 1 1 0 USP8 interacting CorA PF01544.18 EAQ82871.1 - 0.074 12.3 1.5 0.17 11.1 1.5 1.5 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein HMMR_N PF15905.5 EAQ82871.1 - 0.091 12.2 0.4 0.16 11.4 0.4 1.2 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal CENP-F_leu_zip PF10473.9 EAQ82871.1 - 0.092 12.8 0.8 0.25 11.3 0.8 1.7 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PKcGMP_CC PF16808.5 EAQ82871.1 - 0.16 11.9 0.8 0.51 10.2 0.8 1.9 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF3584 PF12128.8 EAQ82871.1 - 0.32 8.5 4.6 0.51 7.8 4.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) zf-RVT PF13966.6 EAQ82871.1 - 0.75 10.5 0.0 0.75 10.5 0.0 3.3 3 1 1 4 4 2 0 zinc-binding in reverse transcriptase YlqD PF11068.8 EAQ82871.1 - 0.86 10.0 3.6 2.9 8.3 3.6 1.9 1 0 0 1 1 1 0 YlqD protein Exonuc_VII_L PF02601.15 EAQ82871.1 - 6.5 6.2 8.4 1.8 8.0 4.5 2.0 2 0 0 2 2 2 0 Exonuclease VII, large subunit RVT_1 PF00078.27 EAQ82872.1 - 4e-07 29.8 0.0 8.3e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Med30 PF11315.8 EAQ82872.1 - 0.23 11.7 2.4 0.7 10.1 1.4 2.3 2 0 0 2 2 2 0 Mediator complex subunit 30 NPV_P10 PF05531.12 EAQ82872.1 - 0.24 11.9 10.4 2.9 8.4 0.0 5.2 3 3 2 5 5 5 0 Nucleopolyhedrovirus P10 protein RmuC PF02646.16 EAQ82872.1 - 0.29 10.2 4.3 0.26 10.4 0.1 2.8 2 2 1 3 3 3 0 RmuC family AAA_13 PF13166.6 EAQ82872.1 - 0.53 8.9 5.7 2.6 6.6 0.6 2.2 2 0 0 2 2 2 0 AAA domain Tropomyosin_1 PF12718.7 EAQ82872.1 - 0.64 10.2 6.0 0.54 10.4 0.4 3.2 2 1 1 3 3 3 0 Tropomyosin like Med9 PF07544.13 EAQ82872.1 - 1.9 8.7 5.8 21 5.3 0.3 4.0 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 GAS PF13851.6 EAQ82872.1 - 2.6 7.4 11.9 2.6 7.3 0.9 3.3 3 2 0 3 3 3 0 Growth-arrest specific micro-tubule binding She9_MDM33 PF05546.11 EAQ82872.1 - 3.5 7.4 7.0 18 5.1 0.1 3.1 3 2 0 3 3 3 0 She9 / Mdm33 family IFT57 PF10498.9 EAQ82872.1 - 3.6 6.5 8.5 0.81 8.6 1.2 2.3 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 DUF720 PF05302.11 EAQ82872.1 - 4.5 7.1 11.6 11 5.9 8.7 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF720) DUF1664 PF07889.12 EAQ82872.1 - 5.7 7.0 8.6 5 7.2 0.7 3.8 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) Abhydrolase_6 PF12697.7 EAQ82873.1 - 1.8e-12 48.4 11.4 2.2e-12 48.0 11.4 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EAQ82873.1 - 6e-12 45.8 0.4 8e-12 45.3 0.4 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EAQ82873.1 - 2.3e-05 23.8 0.0 3.7e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.20 EAQ82873.1 - 0.022 14.4 0.0 0.035 13.8 0.0 1.3 1 0 0 1 1 1 0 Putative esterase MMPL PF03176.15 EAQ82874.1 - 0.15 10.9 2.5 1 8.2 0.2 2.2 2 0 0 2 2 2 0 MMPL family p450 PF00067.22 EAQ82875.1 - 8.8e-21 74.2 0.0 2e-20 73.0 0.0 1.5 1 0 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.25 EAQ82876.1 - 2.1e-08 33.8 0.0 3.8e-08 33.0 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain MFS_1 PF07690.16 EAQ82877.1 - 1.2e-26 93.5 29.7 1.2e-26 93.5 29.7 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily EptA_B_N PF08019.12 EAQ82877.1 - 0.51 10.2 5.1 13 5.6 0.0 3.1 3 1 1 4 4 4 0 Phosphoethanolamine transferase EptA/EptB CTP_synth_N PF06418.14 EAQ82878.1 - 3.1e-101 338.2 0.0 4.4e-101 337.6 0.0 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus Tannase PF07519.11 EAQ82878.1 - 1e-87 295.1 0.3 1.4e-87 294.5 0.3 1.2 1 0 0 1 1 1 1 Tannase and feruloyl esterase GATase PF00117.28 EAQ82878.1 - 1.1e-51 175.3 0.0 1.6e-51 174.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EAQ82878.1 - 0.0038 17.0 0.0 0.012 15.3 0.0 1.8 1 1 0 1 1 1 1 Peptidase C26 Peptidase_S10 PF00450.22 EAQ82878.1 - 0.12 11.8 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Serine carboxypeptidase MFS_1 PF07690.16 EAQ82879.1 - 2.1e-38 132.2 65.5 1.2e-36 126.4 62.3 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EAQ82879.1 - 1.1e-09 37.4 19.9 1.8e-09 36.6 19.9 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Epimerase PF01370.21 EAQ82880.1 - 0.013 14.9 0.7 0.31 10.5 0.7 2.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EAQ82880.1 - 0.033 13.3 0.9 0.071 12.2 0.4 1.8 2 1 0 2 2 2 0 RmlD substrate binding domain GAPES1 PF17155.4 EAQ82880.1 - 0.056 12.8 0.1 1.6 7.9 0.0 2.1 2 0 0 2 2 2 0 Gammaproteobacterial periplasmic sensor domain NAD_binding_10 PF13460.6 EAQ82880.1 - 0.1 12.4 0.3 1.1 9.2 0.3 2.1 1 1 0 1 1 1 0 NAD(P)H-binding adh_short_C2 PF13561.6 EAQ82881.1 - 5.7e-12 45.7 0.3 8.3e-12 45.2 0.3 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EAQ82881.1 - 2.6e-10 40.1 0.1 5.4e-10 39.1 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 EAQ82881.1 - 0.0091 15.5 0.0 0.011 15.2 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family HET PF06985.11 EAQ82882.1 - 8e-26 91.1 0.0 1.7e-25 90.1 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) p450 PF00067.22 EAQ82883.1 - 1.3e-59 202.1 0.0 2.7e-40 138.5 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 NDUF_B8 PF05821.11 EAQ82884.1 - 1.2e-05 25.3 1.2 2.1e-05 24.4 1.2 1.4 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) SNF2_N PF00176.23 EAQ82885.1 - 6.1e-66 222.5 0.2 1.3e-65 221.4 0.2 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EAQ82885.1 - 9.4e-18 64.6 0.0 3.9e-17 62.6 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EAQ82885.1 - 1.1e-09 38.6 0.0 2.4e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAQ82885.1 - 0.00079 19.2 0.0 0.0021 17.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase HSA PF07529.13 EAQ82885.1 - 0.0034 17.7 12.4 0.021 15.1 12.4 2.3 1 1 0 1 1 1 1 HSA Trimer_CC PF08954.11 EAQ82885.1 - 0.026 14.1 0.0 0.093 12.3 0.0 2.1 1 0 0 1 1 1 0 Trimerisation motif HDA2-3 PF11496.8 EAQ82885.1 - 0.029 13.6 0.0 1.8 7.7 0.0 2.6 2 0 0 2 2 2 0 Class II histone deacetylase complex subunits 2 and 3 Sld5 PF05916.11 EAQ82887.1 - 0.064 13.7 0.0 0.074 13.5 0.0 1.1 1 0 0 1 1 1 0 GINS complex protein NAD_binding_10 PF13460.6 EAQ82888.1 - 4.4e-10 39.7 0.0 6.6e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EAQ82888.1 - 6.8e-09 35.6 0.0 9.6e-09 35.1 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 EAQ82888.1 - 2.3e-06 27.9 0.0 4.3e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 EAQ82888.1 - 0.001 18.6 0.1 0.0016 18.0 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.17 EAQ82888.1 - 0.031 14.8 0.2 0.067 13.8 0.2 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Semialdhyde_dh PF01118.24 EAQ82888.1 - 0.04 14.3 0.1 0.074 13.5 0.1 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.10 EAQ82888.1 - 0.048 13.6 0.1 0.078 12.9 0.1 1.3 1 0 0 1 1 1 0 KR domain DapB_N PF01113.20 EAQ82888.1 - 0.054 13.6 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus GMC_oxred_N PF00732.19 EAQ82889.1 - 3.6e-29 102.1 0.0 2.1e-27 96.3 0.0 2.1 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EAQ82889.1 - 1.1e-28 100.6 0.0 3.4e-28 99.0 0.0 1.9 2 0 0 2 2 2 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 EAQ82889.1 - 0.00022 20.5 0.0 0.00066 19.0 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EAQ82889.1 - 0.00053 19.2 0.1 0.038 13.1 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 EAQ82889.1 - 0.022 15.0 0.0 0.05 13.8 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EAQ82889.1 - 0.038 13.2 1.1 2.3 7.4 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EAQ82889.1 - 0.055 12.8 0.2 0.25 10.7 0.0 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EAQ82889.1 - 0.058 12.6 0.1 0.12 11.6 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.22 EAQ82889.1 - 0.1 11.6 0.0 0.82 8.7 0.0 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A Fructosamin_kin PF03881.14 EAQ82890.1 - 4e-31 108.3 0.0 5.3e-31 107.9 0.0 1.1 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 EAQ82890.1 - 0.00019 21.5 0.0 0.00031 20.8 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Abhydrolase_6 PF12697.7 EAQ82891.1 - 3.9e-08 34.2 4.1 4.8e-08 33.9 4.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EAQ82891.1 - 2.6e-05 23.6 0.0 3.7e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EAQ82891.1 - 7.2e-05 22.6 0.0 0.00011 21.9 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 EAQ82891.1 - 0.0032 17.1 0.0 0.0044 16.7 0.0 1.2 1 0 0 1 1 1 1 Putative esterase DUF2101 PF09874.9 EAQ82893.1 - 0.012 15.4 2.3 0.029 14.1 2.3 1.6 1 0 0 1 1 1 0 Predicted membrane protein (DUF2101) Myotoxins PF00819.17 EAQ82895.1 - 0.045 14.0 0.1 7.9 6.8 0.0 2.5 2 0 0 2 2 2 0 Myotoxin, crotamine MscS_TM PF12794.7 EAQ82896.1 - 0.22 10.3 3.4 0.35 9.7 3.4 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 DUF86 PF01934.17 EAQ82898.1 - 0.052 13.4 0.1 0.084 12.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF86 zf-RVT PF13966.6 EAQ82900.1 - 0.032 14.9 0.1 0.15 12.8 0.0 2.1 2 0 0 2 2 2 0 zinc-binding in reverse transcriptase F-box_4 PF15966.5 EAQ82901.1 - 0.099 12.5 0.3 0.16 11.9 0.3 1.3 1 0 0 1 1 1 0 F-box CRAL_TRIO PF00650.20 EAQ82902.1 - 6.4e-14 52.0 0.0 1e-13 51.3 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EAQ82902.1 - 0.0011 19.1 0.0 0.0023 18.1 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 EAQ82902.1 - 0.04 14.1 0.0 0.12 12.5 0.0 1.7 1 1 0 1 1 1 0 Divergent CRAL/TRIO domain PRCC PF10253.9 EAQ82902.1 - 2.5 8.8 8.7 5 7.9 8.7 1.5 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Rax2 PF12768.7 EAQ82903.1 - 0.06 12.8 0.8 0.095 12.1 0.8 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Asp PF00026.23 EAQ82904.1 - 5e-21 75.4 0.0 6.6e-19 68.5 0.0 2.1 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EAQ82904.1 - 6.8e-08 32.9 0.1 7.7e-07 29.5 0.1 2.2 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EAQ82904.1 - 0.0009 19.8 0.2 0.17 12.5 0.0 3.3 2 1 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 EAQ82904.1 - 0.0052 17.3 0.1 0.11 13.1 0.0 2.4 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVT_2 PF07727.14 EAQ82905.1 - 2.3e-49 168.3 0.0 4e-49 167.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 EAQ82905.1 - 1.6e-12 47.7 0.0 5e-12 46.1 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.6 EAQ82905.1 - 0.023 14.5 0.1 0.059 13.2 0.1 1.7 1 0 0 1 1 1 0 GAG-pre-integrase domain HTH_AsnC-type PF13404.6 EAQ82905.1 - 0.15 11.9 0.0 0.52 10.2 0.0 1.9 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Cu-oxidase_3 PF07732.15 EAQ82906.1 - 6.6e-43 145.5 0.5 3.9e-42 143.0 0.1 2.4 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.22 EAQ82906.1 - 1.8e-33 115.9 0.0 4e-33 114.8 0.0 1.6 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 EAQ82906.1 - 2.9e-25 88.6 4.2 1.5e-20 73.3 0.0 3.8 3 1 0 3 3 3 2 Multicopper oxidase OrsD PF12013.8 EAQ82907.1 - 9.5e-06 26.0 0.0 2.3e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Orsellinic acid/F9775 biosynthesis cluster protein D Herpes_glycop PF01528.16 EAQ82907.1 - 0.022 13.6 0.1 0.031 13.1 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus glycoprotein M FAR1 PF03101.15 EAQ82907.1 - 0.029 15.1 0.0 0.065 13.9 0.0 1.6 1 0 0 1 1 1 0 FAR1 DNA-binding domain TPR_10 PF13374.6 EAQ82908.1 - 5.4e-178 572.9 7.0 6.7e-14 51.2 0.0 13.6 13 0 0 13 13 13 13 Tetratricopeptide repeat TPR_12 PF13424.6 EAQ82908.1 - 8.1e-130 423.4 17.3 1.2e-16 60.7 0.0 12.1 1 1 11 12 12 12 12 Tetratricopeptide repeat TPR_7 PF13176.6 EAQ82908.1 - 7.1e-62 201.0 10.2 9.7e-05 22.1 0.0 13.3 13 0 0 13 13 13 12 Tetratricopeptide repeat TPR_17 PF13431.6 EAQ82908.1 - 6.3e-30 101.4 2.4 1.3 9.5 0.0 12.0 12 0 0 12 12 12 10 Tetratricopeptide repeat TPR_1 PF00515.28 EAQ82908.1 - 5.2e-24 83.0 0.2 6.4 6.8 0.0 12.8 13 0 0 13 13 13 2 Tetratricopeptide repeat TPR_2 PF07719.17 EAQ82908.1 - 1.8e-23 80.7 2.1 2.7 8.3 0.0 13.2 13 0 0 13 13 13 2 Tetratricopeptide repeat TPR_16 PF13432.6 EAQ82908.1 - 2.6e-23 82.4 0.0 3.1 8.5 0.0 12.5 10 2 2 12 12 12 2 Tetratricopeptide repeat TPR_4 PF07721.14 EAQ82908.1 - 8.5e-20 69.3 0.0 12 6.9 0.0 13.5 13 0 0 13 13 12 0 Tetratricopeptide repeat TPR_19 PF14559.6 EAQ82908.1 - 9.6e-20 70.9 0.0 1.1 9.8 0.0 12.1 4 3 9 13 13 12 3 Tetratricopeptide repeat TPR_MalT PF17874.1 EAQ82908.1 - 1.4e-18 67.4 20.5 1.1e-06 28.3 3.1 4.7 2 1 3 5 5 5 4 MalT-like TPR region TPR_8 PF13181.6 EAQ82908.1 - 8.2e-11 41.2 11.1 29 5.2 0.0 11.8 12 0 0 12 12 12 0 Tetratricopeptide repeat PNP_UDP_1 PF01048.20 EAQ82908.1 - 2.6e-10 40.0 0.1 8.2e-10 38.3 0.1 1.9 1 0 0 1 1 1 1 Phosphorylase superfamily TPR_5 PF12688.7 EAQ82908.1 - 2.8e-08 34.0 3.7 0.38 11.0 0.0 6.9 3 2 5 8 8 8 1 Tetratrico peptide repeat PPR PF01535.20 EAQ82908.1 - 3.7e-08 33.1 1.3 1.7e+02 2.8 0.0 10.5 12 0 0 12 12 12 0 PPR repeat TPR_14 PF13428.6 EAQ82908.1 - 1.9e-07 31.3 3.6 1.8e+02 3.3 0.0 11.3 12 0 0 12 12 12 0 Tetratricopeptide repeat DUF1897 PF09005.10 EAQ82908.1 - 0.00036 20.0 16.0 20 4.7 0.0 10.1 12 0 0 12 12 12 0 Domain of unknown function (DUF1897) Trans_reg_C PF00486.28 EAQ82908.1 - 0.051 13.7 11.0 3.3 7.8 0.0 7.3 2 2 6 9 9 9 0 Transcriptional regulatory protein, C terminal RVT_1 PF00078.27 EAQ82908.1 - 0.068 12.7 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) RBD-FIP PF09457.10 EAQ82908.1 - 0.12 12.3 0.1 82 3.2 0.0 4.4 2 0 0 2 2 2 0 FIP domain RPN6_N PF18055.1 EAQ82908.1 - 0.19 12.1 8.1 44 4.5 0.0 5.2 3 3 2 6 6 6 0 26S proteasome regulatory subunit RPN6 N-terminal domain cwf21 PF08312.12 EAQ82908.1 - 0.21 11.8 27.4 20 5.5 0.3 6.7 2 2 1 3 3 2 0 cwf21 domain DUF4119 PF13494.6 EAQ82908.1 - 0.44 10.7 16.7 2.3e+02 2.0 0.0 9.1 3 2 8 11 11 11 0 Domain of unknown function, B. Theta Gene description (DUF4119) N36 PF11438.8 EAQ82908.1 - 4.1 7.3 8.9 1.3e+02 2.6 0.0 6.8 11 0 0 11 11 11 0 36-mer N-terminal peptide of the N protein (N36) RNA_pol_3_Rpc31 PF11705.8 EAQ82910.1 - 0.004 17.4 0.0 0.0081 16.4 0.0 1.4 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 PIF1 PF05970.14 EAQ82911.1 - 2.4e-06 27.0 0.8 0.00025 20.4 0.1 2.8 1 1 2 3 3 3 2 PIF1-like helicase UvrD_C_2 PF13538.6 EAQ82911.1 - 0.00014 21.6 0.0 0.00032 20.4 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.14 EAQ82911.1 - 0.00064 17.8 0.0 0.0011 17.0 0.0 1.3 1 0 0 1 1 1 1 Helicase Helitron_like_N PF14214.6 EAQ82912.1 - 1.5e-19 71.0 0.5 2.3e-19 70.4 0.5 1.3 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus MULE PF10551.9 EAQ82913.1 - 1.5e-27 95.8 0.1 3.3e-27 94.7 0.1 1.6 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.18 EAQ82913.1 - 0.0042 16.0 0.0 0.008 15.1 0.0 1.4 1 0 0 1 1 1 1 Transposase, Mutator family Hamartin PF04388.12 EAQ82913.1 - 3.4 6.2 10.5 6.2 5.4 10.5 1.3 1 0 0 1 1 1 0 Hamartin protein His_Phos_1 PF00300.22 EAQ82914.1 - 0.00075 19.2 0.0 0.0021 17.8 0.0 1.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Hce2 PF14856.6 EAQ82915.1 - 3.7e-19 68.9 1.5 6e-19 68.2 1.5 1.3 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor Dna2 PF08696.11 EAQ82915.1 - 0.19 11.6 0.0 0.25 11.1 0.0 1.1 1 0 0 1 1 1 0 DNA replication factor Dna2 NDC10_II PF16787.5 EAQ82916.1 - 1.3e-63 215.0 0.0 2.1e-63 214.3 0.0 1.3 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 MFS_1 PF07690.16 EAQ82916.1 - 5.4e-24 84.8 48.6 1.1e-23 83.8 48.6 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily GCR1_C PF12550.8 EAQ82916.1 - 1.6e-17 63.6 1.3 2.5e-17 63.0 0.4 1.9 2 0 0 2 2 2 1 Transcriptional activator of glycolytic enzymes MFS_2 PF13347.6 EAQ82916.1 - 8.1e-07 27.9 30.0 2.1e-06 26.6 13.5 2.2 1 1 1 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.7 EAQ82916.1 - 0.086 11.7 22.8 0.023 13.6 2.2 2.2 2 0 0 2 2 2 0 MFS_1 like family DUF2516 PF10724.9 EAQ82916.1 - 5.1 7.5 6.6 0.61 10.4 1.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2516) TPR_2 PF07719.17 EAQ82917.1 - 3.7e-10 39.1 11.3 0.0017 18.4 0.0 6.6 7 1 0 7 7 7 3 Tetratricopeptide repeat TPR_1 PF00515.28 EAQ82917.1 - 1.5e-09 37.2 2.2 0.0082 15.9 0.0 5.3 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 EAQ82917.1 - 2.2e-06 28.1 0.2 0.0075 16.8 0.1 4.3 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_MalT PF17874.1 EAQ82917.1 - 0.00012 21.6 0.6 0.00038 19.9 0.1 2.0 2 0 0 2 2 2 1 MalT-like TPR region TPR_8 PF13181.6 EAQ82917.1 - 0.00025 21.0 0.7 4.3 7.8 0.0 5.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.6 EAQ82917.1 - 0.00031 21.3 11.6 15 6.7 0.0 6.8 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_11 PF13414.6 EAQ82917.1 - 0.0025 17.4 3.5 0.9 9.3 0.1 4.0 5 0 0 5 5 5 2 TPR repeat TPR_12 PF13424.6 EAQ82917.1 - 0.0038 17.5 6.8 1.7 9.0 0.4 5.7 4 2 2 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 EAQ82917.1 - 0.0092 16.6 11.7 6 7.6 0.3 6.5 8 0 0 8 8 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 EAQ82917.1 - 0.011 16.1 0.2 80 4.0 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EAQ82917.1 - 0.024 14.9 0.0 3 8.1 0.0 3.8 2 1 2 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 EAQ82917.1 - 0.028 14.4 7.2 0.04 13.9 0.1 4.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_4 PF07721.14 EAQ82917.1 - 0.072 13.8 14.7 1.4 9.7 0.1 5.1 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 EAQ82917.1 - 1.3 9.0 8.1 1.1 9.2 0.1 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat NMO PF03060.15 EAQ82918.1 - 1.8e-29 103.2 3.5 5.8e-29 101.5 3.5 1.7 1 1 0 1 1 1 1 Nitronate monooxygenase FMN_dh PF01070.18 EAQ82918.1 - 1.7e-08 33.9 0.7 2.5e-08 33.4 0.7 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 EAQ82918.1 - 1.3e-05 24.4 0.8 2.2e-05 23.6 0.8 1.3 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 EAQ82918.1 - 6.3e-05 22.3 0.4 0.00011 21.4 0.4 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase DHO_dh PF01180.21 EAQ82918.1 - 0.0024 17.1 0.2 0.0039 16.4 0.2 1.3 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase Fungal_trans PF04082.18 EAQ82919.1 - 2.8e-06 26.6 0.0 4.1e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DDE_1 PF03184.19 EAQ82921.1 - 3.6e-28 98.4 0.0 5.9e-28 97.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 EAQ82921.1 - 0.00069 19.4 0.0 0.0023 17.7 0.0 1.8 1 0 0 1 1 1 1 DDE superfamily endonuclease Prominin PF05478.11 EAQ82921.1 - 0.19 9.6 2.1 0.29 9.0 2.1 1.2 1 0 0 1 1 1 0 Prominin zf-CCHC PF00098.23 EAQ82921.1 - 1.2 9.3 4.4 2.6 8.3 4.4 1.6 1 0 0 1 1 1 0 Zinc knuckle RVT_1 PF00078.27 EAQ82922.1 - 1.4e-29 103.2 0.0 8.8e-29 100.6 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 EAQ82922.1 - 2e-17 63.1 0.0 1.2e-16 60.6 0.0 2.5 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase zf-CCHC PF00098.23 EAQ82922.1 - 0.0021 18.1 1.7 0.0021 18.1 1.7 2.8 2 0 0 2 2 2 1 Zinc knuckle SlyX PF04102.12 EAQ82922.1 - 0.0049 17.5 5.3 0.06 14.0 5.3 2.7 1 1 0 1 1 1 1 SlyX USP8_interact PF08941.10 EAQ82922.1 - 0.062 13.1 0.1 0.15 11.9 0.1 1.7 1 0 0 1 1 1 0 USP8 interacting PKcGMP_CC PF16808.5 EAQ82922.1 - 0.23 11.3 1.7 0.27 11.1 0.2 1.8 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase zf-RVT PF13966.6 EAQ82922.1 - 0.6 10.9 0.0 0.6 10.9 0.0 2.9 3 0 0 3 3 3 0 zinc-binding in reverse transcriptase Herpes_pp85 PF04637.12 EAQ82922.1 - 1.1 7.6 3.5 1.8 6.9 3.5 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) adh_short PF00106.25 EAQ82923.1 - 1.6e-19 70.2 0.1 2.2e-14 53.4 0.0 2.4 1 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EAQ82923.1 - 2e-12 47.2 0.0 7.3e-08 32.2 0.0 2.4 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Fungal_trans PF04082.18 EAQ82923.1 - 1.5e-07 30.8 0.1 3.8e-07 29.4 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain KR PF08659.10 EAQ82923.1 - 5.8e-05 23.1 0.5 0.00014 21.8 0.0 1.8 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 EAQ82923.1 - 0.073 12.5 0.0 3.7 6.9 0.0 2.2 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family GMC_oxred_N PF00732.19 EAQ82924.1 - 2.4e-36 125.6 0.1 2.5e-23 82.9 0.0 2.2 2 0 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.13 EAQ82924.1 - 9.8e-29 100.7 0.0 1.6e-28 100.1 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 EAQ82924.1 - 5e-06 26.3 0.1 0.00021 21.0 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EAQ82924.1 - 1.4e-05 25.2 0.1 5.5e-05 23.3 0.1 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EAQ82924.1 - 5.2e-05 22.5 0.1 0.056 12.5 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.6 EAQ82924.1 - 0.0034 16.7 0.1 0.099 11.9 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EAQ82924.1 - 0.028 14.4 0.0 0.065 13.2 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 EAQ82924.1 - 0.029 13.6 0.1 0.11 11.7 0.1 2.0 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EAQ82924.1 - 0.03 13.4 0.0 0.057 12.5 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein TrkA_N PF02254.18 EAQ82924.1 - 0.065 13.5 0.2 0.16 12.2 0.0 1.8 2 0 0 2 2 2 0 TrkA-N domain K_oxygenase PF13434.6 EAQ82924.1 - 0.083 12.0 0.0 6.4 5.8 0.0 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 EAQ82924.1 - 0.11 11.2 0.0 0.31 9.7 0.0 1.7 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox PF00070.27 EAQ82924.1 - 0.13 12.8 0.1 0.13 12.8 0.1 2.5 3 1 1 4 4 3 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EAQ82925.1 - 7.5e-16 58.2 0.0 7.9e-12 45.0 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EAQ82925.1 - 4.5e-05 22.9 2.4 0.0057 15.9 1.8 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EAQ82925.1 - 6.6e-05 21.8 0.1 0.0032 16.2 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 EAQ82925.1 - 7.9e-05 21.9 1.4 0.00011 21.4 0.2 1.8 2 1 1 3 3 3 1 FAD binding domain DAO PF01266.24 EAQ82925.1 - 0.00011 21.9 0.0 0.00018 21.2 0.0 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 EAQ82925.1 - 0.00023 20.4 0.1 0.18 10.9 0.0 2.2 1 1 1 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.22 EAQ82925.1 - 0.00025 20.3 0.7 0.016 14.3 0.1 2.3 1 1 1 2 2 2 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 EAQ82925.1 - 0.00065 19.9 0.1 0.0017 18.6 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EAQ82925.1 - 0.0023 17.9 1.5 1.1 9.2 0.5 2.6 1 1 0 2 2 2 2 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 EAQ82925.1 - 0.0026 17.1 0.1 0.0042 16.4 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 EAQ82925.1 - 0.0053 16.0 1.1 0.067 12.4 0.3 2.4 2 1 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.7 EAQ82925.1 - 0.012 14.9 1.2 0.029 13.7 0.3 1.8 1 1 0 2 2 2 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EAQ82925.1 - 0.055 12.5 0.1 0.4 9.7 0.0 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein AMP-binding PF00501.28 EAQ82926.1 - 2e-44 151.9 0.1 4.6e-28 98.0 0.0 2.1 1 1 1 2 2 2 2 AMP-binding enzyme DUF2722 PF10846.8 EAQ82927.1 - 0.00011 21.4 10.6 0.00011 21.4 10.6 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) Zn_clus PF00172.18 EAQ82927.1 - 0.0013 18.8 6.5 0.0013 18.8 6.5 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SpoIIP PF07454.11 EAQ82927.1 - 0.022 14.3 1.2 0.032 13.7 1.2 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Zip PF02535.22 EAQ82927.1 - 0.23 10.6 2.9 0.22 10.7 0.7 1.8 2 0 0 2 2 2 0 ZIP Zinc transporter DUF4834 PF16118.5 EAQ82927.1 - 0.23 12.4 7.4 1.1 10.3 6.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Suf PF05843.14 EAQ82927.1 - 0.45 10.4 12.2 0.16 12.0 9.4 1.6 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Spt20 PF12090.8 EAQ82927.1 - 1.5 8.4 31.0 0.034 13.8 24.1 1.8 2 0 0 2 2 2 0 Spt20 family DUF3464 PF11947.8 EAQ82927.1 - 1.6 8.5 6.2 3.4 7.4 6.2 1.6 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 DUF4050 PF13259.6 EAQ82927.1 - 1.6 9.0 10.6 0.7 10.2 5.4 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF4050) Hid1 PF12722.7 EAQ82927.1 - 2.1 6.3 5.2 4.1 5.4 5.2 1.4 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein eIF-3_zeta PF05091.12 EAQ82927.1 - 6.2 5.7 9.7 9.1 5.1 9.7 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) p450 PF00067.22 EAQ82928.1 - 7.8e-66 222.7 0.0 9.9e-66 222.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Phage_Mu_Gp45 PF06890.12 EAQ82928.1 - 0.061 13.1 0.0 0.2 11.4 0.0 1.8 2 0 0 2 2 2 0 Bacteriophage Mu Gp45 protein Ribo_biogen_C PF04034.13 EAQ82928.1 - 0.16 11.7 0.9 42 3.9 0.0 3.4 3 1 1 4 4 4 0 Ribosome biogenesis protein, C-terminal CMD PF02627.20 EAQ82930.1 - 9.1e-06 25.6 0.3 0.00078 19.4 0.0 2.6 3 1 0 3 3 3 2 Carboxymuconolactone decarboxylase family MFS_1 PF07690.16 EAQ82931.1 - 4.6e-33 114.6 64.7 4.4e-26 91.7 50.5 3.2 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EAQ82931.1 - 1.1e-09 37.7 8.1 1.1e-09 37.7 8.1 3.3 2 1 1 3 3 3 2 Sugar (and other) transporter OATP PF03137.20 EAQ82931.1 - 0.21 9.8 15.2 0.22 9.8 2.6 2.7 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family ADH_zinc_N PF00107.26 EAQ82932.1 - 2.2e-08 34.2 0.1 3.6e-08 33.4 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Peripla_BP_4 PF13407.6 EAQ82932.1 - 0.066 12.8 0.9 0.12 12.0 0.9 1.4 1 1 0 1 1 1 0 Periplasmic binding protein domain Methyltransf_3 PF01596.17 EAQ82933.1 - 4.7e-27 94.6 0.0 5.7e-27 94.3 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 EAQ82933.1 - 3.5e-16 60.2 0.0 6.5e-16 59.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAQ82933.1 - 1.6e-11 44.2 0.0 2e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAQ82933.1 - 7.7e-08 33.0 0.0 2.1e-07 31.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EAQ82933.1 - 4.1e-07 30.6 0.0 1.4e-06 28.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Cons_hypoth95 PF03602.15 EAQ82933.1 - 4.5e-05 23.2 0.0 6.4e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 PCMT PF01135.19 EAQ82933.1 - 4.8e-05 23.2 0.0 6.3e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.12 EAQ82933.1 - 0.0024 18.6 0.0 0.0042 17.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EAQ82933.1 - 0.0062 16.4 0.0 0.018 14.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EAQ82933.1 - 0.0067 15.8 0.0 0.0092 15.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family UPF0020 PF01170.18 EAQ82933.1 - 0.047 13.4 0.0 0.064 12.9 0.0 1.2 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_32 PF13679.6 EAQ82933.1 - 0.082 12.9 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_15 PF09445.10 EAQ82933.1 - 0.15 11.6 0.0 0.24 11.0 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase AMP-binding PF00501.28 EAQ82934.1 - 3.2e-156 520.2 0.0 4.3e-84 282.6 0.1 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.20 EAQ82934.1 - 1.7e-72 244.6 0.0 2.2e-34 118.9 0.0 5.2 5 0 0 5 5 5 5 Condensation domain PP-binding PF00550.25 EAQ82934.1 - 2.6e-17 62.9 0.0 6e-09 36.1 0.0 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EAQ82934.1 - 2.7e-11 44.3 0.1 6.3e-07 30.3 0.0 2.9 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain Transferase PF02458.15 EAQ82934.1 - 0.091 11.4 0.0 4.4 5.8 0.0 2.2 2 0 0 2 2 2 0 Transferase family Adap_comp_sub PF00928.21 EAQ82935.1 - 1.8e-71 240.7 0.0 2.2e-64 217.4 0.0 2.1 1 1 1 2 2 2 2 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EAQ82935.1 - 7.1e-05 22.8 0.2 0.00013 22.0 0.2 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 EAQ82935.1 - 0.022 14.2 0.0 0.046 13.2 0.0 1.5 1 0 0 1 1 1 0 Muniscin C-terminal mu homology domain MCU PF04678.13 EAQ82936.1 - 0.25 11.4 2.1 1.1 9.4 0.2 2.1 2 0 0 2 2 2 0 Mitochondrial calcium uniporter Sugarporin_N PF11471.8 EAQ82936.1 - 0.91 9.5 4.2 2.5 8.1 4.2 1.8 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension Bestrophin PF01062.21 EAQ82937.1 - 9.4e-34 117.1 0.0 1.7e-33 116.3 0.0 1.3 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel PHO4 PF01384.20 EAQ82937.1 - 0.038 13.0 0.7 0.1 11.6 0.7 1.7 1 1 0 1 1 1 0 Phosphate transporter family MFS_1 PF07690.16 EAQ82938.1 - 4.9e-28 98.1 21.3 7.8e-28 97.4 21.3 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EAQ82938.1 - 1.2e-07 31.0 11.0 5.3e-07 28.8 11.0 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter Wzy_C PF04932.15 EAQ82938.1 - 0.025 14.2 0.5 0.025 14.2 0.5 3.0 3 1 0 3 3 3 0 O-Antigen ligase Patatin PF01734.22 EAQ82939.1 - 9.1e-20 71.7 0.1 1.9e-18 67.4 0.1 2.6 2 1 0 2 2 2 1 Patatin-like phospholipase DUF2075 PF09848.9 EAQ82939.1 - 0.035 13.4 0.0 0.051 12.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.22 EAQ82939.1 - 0.069 13.5 0.0 0.14 12.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_16 PF13191.6 EAQ82939.1 - 0.085 13.2 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 EAQ82939.1 - 0.089 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_29 PF13555.6 EAQ82939.1 - 0.13 12.1 0.0 0.45 10.3 0.0 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain RVT_1 PF00078.27 EAQ82940.1 - 6.2e-30 104.4 0.0 3.4e-22 79.0 0.0 2.3 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) PLDc_2 PF13091.6 EAQ82942.1 - 1.1e-20 73.8 0.0 1.9e-12 47.2 0.0 2.6 2 2 0 2 2 2 2 PLD-like domain PLDc PF00614.22 EAQ82942.1 - 0.00016 21.7 0.0 0.028 14.6 0.0 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif Regulator_TrmB PF11495.8 EAQ82942.1 - 0.14 11.3 0.0 3.5 6.7 0.0 2.8 3 0 0 3 3 3 0 Archaeal transcriptional regulator TrmB ThuA PF06283.11 EAQ82943.1 - 4.6e-59 200.2 0.1 4.7e-57 193.6 0.1 2.0 1 1 0 1 1 1 1 Trehalose utilisation Glyco_hydro_6 PF01341.17 EAQ82944.1 - 2.9e-103 345.8 0.2 3.8e-103 345.4 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 CBM_1 PF00734.18 EAQ82944.1 - 9.9e-14 51.0 16.6 3.2e-13 49.4 16.6 2.0 1 0 0 1 1 1 1 Fungal cellulose binding domain Opi1 PF08618.10 EAQ82945.1 - 2e-26 93.2 11.5 2.5e-20 73.2 0.2 3.7 3 1 0 4 4 4 3 Transcription factor Opi1 DDE_1 PF03184.19 EAQ82946.1 - 2.8e-18 66.2 0.1 4.8e-18 65.4 0.1 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 EAQ82946.1 - 0.001 18.9 0.1 0.0037 17.0 0.1 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease DUF4470 PF14737.6 EAQ82947.1 - 3.7e-13 49.5 0.0 6.5e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) TPR_2 PF07719.17 EAQ82947.1 - 7.2e-11 41.3 1.6 0.00033 20.5 1.2 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 EAQ82947.1 - 3.2e-07 29.9 1.7 2.8e-06 26.9 0.2 2.4 1 1 1 2 2 2 1 TPR repeat TPR_8 PF13181.6 EAQ82947.1 - 2.1e-06 27.5 3.6 0.015 15.5 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 EAQ82947.1 - 2.2e-06 28.1 0.2 0.0039 17.7 0.2 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 EAQ82947.1 - 4.3e-06 26.9 0.4 0.0028 17.9 0.1 3.1 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 EAQ82947.1 - 4.2e-05 23.2 3.1 0.088 12.7 0.7 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 EAQ82947.1 - 5.5e-05 22.9 1.1 0.0025 17.7 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 EAQ82947.1 - 0.07 13.8 4.0 0.26 12.0 0.2 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 EAQ82947.1 - 0.14 12.8 1.0 64 4.5 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 EAQ82947.1 - 0.14 13.0 6.4 7.1 7.7 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_20 PF14561.6 EAQ82947.1 - 0.16 12.3 0.1 0.87 10.0 0.0 2.3 2 1 0 2 2 2 0 Tetratricopeptide repeat Adap_comp_sub PF00928.21 EAQ82948.1 - 6e-91 304.5 0.0 1e-90 303.7 0.0 1.4 2 0 0 2 2 2 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EAQ82948.1 - 1.3e-06 28.4 3.2 4.3e-06 26.7 3.2 1.9 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Inhibitor_G39P PF11417.8 EAQ82949.1 - 0.14 12.7 0.1 0.74 10.4 0.1 1.9 2 0 0 2 2 2 0 Loader and inhibitor of phage G40P HeLo PF14479.6 EAQ82951.1 - 7.8e-39 133.6 0.4 1.2e-38 133.1 0.4 1.3 1 0 0 1 1 1 1 Prion-inhibition and propagation Pkinase PF00069.25 EAQ82951.1 - 0.00075 18.9 0.0 0.0013 18.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ82951.1 - 0.0013 18.1 0.0 0.0029 16.9 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EAQ82952.1 - 7.3e-35 120.6 0.0 1.3e-34 119.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ82952.1 - 5.7e-25 88.1 0.0 9.1e-25 87.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_2 PF12796.7 EAQ82952.1 - 4.2e-13 49.7 0.0 7.4e-07 29.7 0.0 2.5 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 EAQ82952.1 - 2.2e-06 27.9 0.1 0.16 12.4 0.1 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 EAQ82952.1 - 1.7e-05 25.3 0.4 7.6e-05 23.2 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAQ82952.1 - 0.00045 20.4 0.2 0.48 11.2 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 EAQ82952.1 - 0.0015 18.8 0.7 0.012 15.9 0.1 2.8 2 1 1 3 3 3 1 Ankyrin repeats (many copies) PhoU_div PF01865.16 EAQ82952.1 - 0.15 11.4 0.0 0.39 10.0 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function DUF47 DUF3574 PF12098.8 EAQ82953.1 - 0.048 13.4 0.0 0.28 11.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3574) CBP_BcsO PF17037.5 EAQ82954.1 - 0.01 16.0 0.3 0.022 14.9 0.3 1.6 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsO PAN_4 PF14295.6 EAQ82954.1 - 0.022 14.7 0.1 0.092 12.7 0.1 2.2 1 1 0 1 1 1 0 PAN domain Abhydrolase_3 PF07859.13 EAQ82955.1 - 2.2e-15 57.1 0.0 1e-12 48.4 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EAQ82955.1 - 5.1e-06 26.1 0.0 0.00084 18.9 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family CBM_1 PF00734.18 EAQ82956.1 - 1.1e-11 44.4 13.4 1.1e-11 44.4 13.4 2.3 2 0 0 2 2 2 1 Fungal cellulose binding domain AXE1 PF05448.12 EAQ82956.1 - 0.0038 16.0 0.0 0.0079 14.9 0.0 1.4 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Aminotran_5 PF00266.19 EAQ82957.1 - 0.00067 18.7 0.1 0.02 13.8 0.1 2.1 2 0 0 2 2 2 2 Aminotransferase class-V RVT_1 PF00078.27 EAQ82958.1 - 3.3e-48 164.1 0.0 2.1e-47 161.5 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 EAQ82958.1 - 4.6e-13 49.1 0.0 1.2e-12 47.7 0.0 1.8 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 EAQ82958.1 - 6.5e-08 32.4 0.2 2.3e-07 30.6 0.2 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Thymidylate_kin PF02223.17 EAQ82960.1 - 7.7e-40 136.5 0.0 3.1e-38 131.3 0.0 2.0 2 0 0 2 2 2 1 Thymidylate kinase AAA_28 PF13521.6 EAQ82960.1 - 0.00031 21.0 0.0 0.00067 19.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 EAQ82960.1 - 0.0016 18.0 0.0 0.0029 17.1 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_18 PF13238.6 EAQ82960.1 - 0.093 13.3 0.0 0.13 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain GTP_cyclohydroI PF01227.22 EAQ82961.1 - 1.3e-56 190.8 2.5 1.5e-56 190.7 2.5 1.0 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 EAQ82961.1 - 0.00047 20.3 0.0 0.00069 19.7 0.0 1.2 1 0 0 1 1 1 1 QueF-like protein DegT_DnrJ_EryC1 PF01041.17 EAQ82961.1 - 0.017 14.4 0.0 0.019 14.3 0.0 1.1 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family TAFII28 PF04719.14 EAQ82962.1 - 3.5e-24 84.7 0.9 1.4e-16 60.3 0.1 2.8 2 1 0 2 2 2 2 hTAFII28-like protein conserved region Ribosomal_L27 PF01016.19 EAQ82964.1 - 1.1e-26 92.7 0.8 2.6e-26 91.4 0.8 1.7 1 0 0 1 1 1 1 Ribosomal L27 protein IPP-2 PF04979.14 EAQ82964.1 - 9.6e-21 74.9 7.5 9.6e-21 74.9 7.5 3.1 2 1 0 2 2 2 1 Protein phosphatase inhibitor 2 (IPP-2) ECR1_N PF14382.6 EAQ82964.1 - 0.096 12.5 0.2 0.34 10.8 0.2 2.0 1 0 0 1 1 1 0 Exosome complex exonuclease RRP4 N-terminal region Fungal_trans_2 PF11951.8 EAQ82965.1 - 0.088 11.6 0.3 1.3 7.8 0.1 2.1 2 0 0 2 2 2 0 Fungal specific transcription factor domain Sugar_tr PF00083.24 EAQ82966.1 - 2.7e-82 277.0 19.7 3.3e-82 276.8 19.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EAQ82966.1 - 3.1e-15 56.0 35.4 4.6e-11 42.3 11.9 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EAQ82966.1 - 0.00033 19.7 7.1 0.00033 19.7 7.1 1.8 2 1 1 3 3 3 1 MFS_1 like family MIOX PF05153.15 EAQ82967.1 - 2.2e-121 404.1 0.0 2.7e-121 403.8 0.0 1.1 1 0 0 1 1 1 1 Myo-inositol oxygenase NOG1_N PF17835.1 EAQ82967.1 - 0.056 13.4 1.3 1.5 8.8 0.1 2.5 2 1 0 2 2 2 0 NOG1 N-terminal helical domain Pkinase PF00069.25 EAQ82968.1 - 0.21 10.9 0.0 0.34 10.2 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain UvdE PF03851.14 EAQ82969.1 - 2.3e-118 394.4 0.0 3.1e-118 394.0 0.0 1.2 1 0 0 1 1 1 1 UV-endonuclease UvdE DUF2145 PF09916.9 EAQ82969.1 - 0.14 11.8 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2145) PARP PF00644.20 EAQ82970.1 - 1.7e-54 184.4 0.0 4.1e-54 183.1 0.0 1.7 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 EAQ82970.1 - 1.5e-45 154.6 0.2 2.5e-45 153.9 0.2 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 EAQ82970.1 - 7.5e-24 83.6 0.2 1.7e-23 82.5 0.2 1.6 1 0 0 1 1 1 1 WGR domain Zn_clus PF00172.18 EAQ82970.1 - 8e-15 54.7 26.1 1.9e-08 34.3 6.6 2.6 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain BRCT PF00533.26 EAQ82970.1 - 2.3e-11 43.9 0.0 4.4e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Fungal_trans PF04082.18 EAQ82970.1 - 7.5e-10 38.3 1.5 1e-08 34.6 0.6 2.4 2 1 0 2 2 2 1 Fungal specific transcription factor domain PTCB-BRCT PF12738.7 EAQ82970.1 - 9.4e-06 25.5 0.1 2.3e-05 24.3 0.1 1.7 1 0 0 1 1 1 1 twin BRCT domain BRCT_2 PF16589.5 EAQ82970.1 - 0.093 13.1 0.0 0.19 12.2 0.0 1.5 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain SWIRM-assoc_2 PF16496.5 EAQ82970.1 - 5.7 5.7 12.0 11 4.8 12.0 1.3 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal SDA1 PF05285.12 EAQ82970.1 - 9.2 5.6 17.9 8.1 5.8 0.6 2.1 2 0 0 2 2 2 0 SDA1 FAD_binding_4 PF01565.23 EAQ82972.1 - 2.9e-14 53.0 2.8 2.9e-14 53.0 2.8 1.7 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 EAQ82972.1 - 8.7e-08 32.2 0.2 1.8e-07 31.2 0.2 1.5 1 0 0 1 1 1 1 Berberine and berberine like HET PF06985.11 EAQ82974.1 - 5.7e-32 111.1 0.0 9.6e-32 110.4 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MLTR_LBD PF17765.1 EAQ82976.1 - 0.0078 16.3 0.1 0.18 11.9 0.0 2.4 2 0 0 2 2 2 1 MmyB-like transcription regulator ligand binding domain zf-RVT PF13966.6 EAQ82976.1 - 0.055 14.2 1.0 0.19 12.4 0.1 2.4 3 0 0 3 3 3 0 zinc-binding in reverse transcriptase RT_RNaseH PF17917.1 EAQ82976.1 - 0.14 12.4 0.0 0.45 10.8 0.0 1.8 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 EAQ82977.1 - 0.0002 20.9 0.0 0.00031 20.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) FTA2 PF13095.6 EAQ82978.1 - 2e-65 220.4 0.0 2.7e-65 220.0 0.0 1.1 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Glyco_hydro_47 PF01532.20 EAQ82979.1 - 1.9e-150 501.8 0.0 2.2e-150 501.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 SRP54 PF00448.22 EAQ82980.1 - 6.5e-75 251.1 0.8 1.5e-74 249.9 0.7 1.6 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 EAQ82980.1 - 2.3e-32 111.5 3.8 2.3e-32 111.5 3.8 3.3 3 1 1 4 4 4 1 Signal peptide binding domain SRP54_N PF02881.19 EAQ82980.1 - 1.5e-20 73.2 0.1 7.1e-20 71.0 0.1 2.2 2 0 0 2 2 2 1 SRP54-type protein, helical bundle domain cobW PF02492.19 EAQ82980.1 - 1.3e-06 28.2 0.8 9.5e-06 25.3 0.8 2.3 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 EAQ82980.1 - 1.8e-06 28.2 0.2 4.6e-06 26.8 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_17 PF13207.6 EAQ82980.1 - 6.2e-06 26.7 0.6 2.3e-05 24.9 0.1 2.3 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.6 EAQ82980.1 - 0.00023 21.6 0.0 0.00047 20.6 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 EAQ82980.1 - 0.0009 18.6 0.0 0.0018 17.6 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin MMR_HSR1 PF01926.23 EAQ82980.1 - 0.0014 18.7 0.3 0.06 13.4 0.2 2.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase APS_kinase PF01583.20 EAQ82980.1 - 0.0016 18.4 0.0 0.0033 17.3 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase CbiA PF01656.23 EAQ82980.1 - 0.0028 17.7 0.0 0.0064 16.5 0.0 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MeaB PF03308.16 EAQ82980.1 - 0.003 16.6 3.3 0.0035 16.4 0.6 2.4 2 1 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 EAQ82980.1 - 0.0036 17.1 0.0 0.0036 17.1 0.0 2.2 2 2 0 2 2 2 1 AAA domain Thymidylate_kin PF02223.17 EAQ82980.1 - 0.0038 16.9 0.2 0.021 14.5 0.0 2.3 2 0 0 2 2 2 1 Thymidylate kinase AAA_18 PF13238.6 EAQ82980.1 - 0.0048 17.4 0.0 0.013 16.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 EAQ82980.1 - 0.0063 16.5 0.3 0.018 15.1 0.3 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit ATP_bind_1 PF03029.17 EAQ82980.1 - 0.0067 16.2 0.3 0.043 13.6 0.0 2.3 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 EAQ82980.1 - 0.0068 16.7 0.1 0.026 14.8 0.0 2.1 2 0 0 2 2 1 1 AAA domain SRPRB PF09439.10 EAQ82980.1 - 0.014 14.8 0.6 3 7.3 0.9 3.1 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit MobB PF03205.14 EAQ82980.1 - 0.016 15.1 0.1 0.043 13.7 0.0 1.8 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.6 EAQ82980.1 - 0.017 15.4 0.1 0.036 14.3 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 EAQ82980.1 - 0.02 15.2 0.1 0.051 13.9 0.1 1.7 1 0 0 1 1 1 0 AAA domain 6PF2K PF01591.18 EAQ82980.1 - 0.053 12.8 0.0 0.099 11.9 0.0 1.4 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA PF00004.29 EAQ82980.1 - 0.074 13.5 0.2 0.26 11.7 0.2 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Arf PF00025.21 EAQ82980.1 - 0.074 12.5 0.1 0.29 10.5 0.0 2.0 2 0 0 2 2 1 0 ADP-ribosylation factor family NTPase_1 PF03266.15 EAQ82980.1 - 0.11 12.4 0.8 0.73 9.7 0.8 2.2 1 1 0 1 1 1 0 NTPase ABC_tran PF00005.27 EAQ82980.1 - 0.13 12.7 0.6 0.43 11.1 0.1 2.2 2 1 0 2 2 2 0 ABC transporter SKA2 PF16740.5 EAQ82980.1 - 0.47 10.3 3.3 5.2 6.9 0.0 2.7 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 ARGLU PF15346.6 EAQ82981.1 - 0.29 11.0 4.5 0.11 12.3 1.2 1.9 2 0 0 2 2 2 0 Arginine and glutamate-rich 1 GSDH PF07995.11 EAQ82982.1 - 7.5e-07 28.8 0.1 1.6e-06 27.6 0.1 1.6 2 0 0 2 2 2 1 Glucose / Sorbosone dehydrogenase SGL PF08450.12 EAQ82982.1 - 0.026 14.1 0.0 0.085 12.4 0.0 1.9 1 0 0 1 1 1 0 SMP-30/Gluconolactonase/LRE-like region PD40 PF07676.12 EAQ82982.1 - 0.06 13.3 0.0 0.19 11.7 0.0 2.0 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat RVT_1 PF00078.27 EAQ82983.1 - 2.2e-47 161.4 0.0 3.5e-47 160.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RecC_C PF17946.1 EAQ82983.1 - 0.04 13.7 4.2 0.38 10.5 0.6 2.6 2 0 0 2 2 2 0 RecC C-terminal domain Arf PF00025.21 EAQ82984.1 - 3.2e-16 59.3 0.0 4.4e-16 58.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EAQ82984.1 - 0.047 13.2 0.0 0.066 12.7 0.0 1.2 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain Chitin_bind_1 PF00187.19 EAQ82985.1 - 1.6e-05 25.3 70.1 0.00045 20.6 17.3 4.6 4 0 0 4 4 4 3 Chitin recognition protein LysM PF01476.20 EAQ82985.1 - 0.033 14.3 0.0 0.081 13.0 0.0 1.6 2 0 0 2 2 2 0 LysM domain NAPRTase_N PF17767.1 EAQ82986.1 - 0.065 13.6 0.0 0.11 12.9 0.0 1.3 1 0 0 1 1 1 0 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain NMT1_2 PF13379.6 EAQ82986.1 - 0.13 12.0 0.0 0.97 9.1 0.0 2.0 2 0 0 2 2 2 0 NMT1-like family zf-RVT PF13966.6 EAQ82987.1 - 0.11 13.3 0.0 0.33 11.7 0.0 1.8 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase MFS_1 PF07690.16 EAQ82988.1 - 1.3e-32 113.1 27.9 1.3e-32 113.1 27.9 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily SET PF00856.28 EAQ82991.1 - 0.00065 20.1 0.0 0.3 11.5 0.0 2.3 2 0 0 2 2 2 2 SET domain TPR_2 PF07719.17 EAQ82991.1 - 0.18 12.0 0.8 0.95 9.7 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat p450 PF00067.22 EAQ82992.1 - 1.6e-28 99.7 0.0 4.8e-28 98.1 0.0 1.6 2 0 0 2 2 2 1 Cytochrome P450 DUF3237 PF11578.8 EAQ82993.1 - 7.8e-22 77.7 1.5 1.7e-07 31.2 0.1 3.0 2 1 1 3 3 3 3 Protein of unknown function (DUF3237) F_bP_aldolase PF01116.20 EAQ82994.1 - 4.3e-64 216.7 0.0 2.5e-63 214.2 0.0 2.0 1 1 0 1 1 1 1 Fructose-bisphosphate aldolase class-II DUF829 PF05705.14 EAQ82995.1 - 3.7e-70 236.5 0.0 4.3e-70 236.3 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) 4HBT_3 PF13622.6 EAQ82996.1 - 2.1e-47 162.5 0.0 2.4e-47 162.3 0.0 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily p450 PF00067.22 EAQ82998.1 - 1.2e-49 169.4 0.0 1.7e-49 168.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Ribonucleas_3_3 PF14622.6 EAQ83000.1 - 4.1e-31 107.8 0.0 6.1e-31 107.2 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease-III-like UBA PF00627.31 EAQ83000.1 - 0.19 11.7 0.1 0.4 10.7 0.1 1.5 1 0 0 1 1 1 0 UBA/TS-N domain HAT_KAT11 PF08214.11 EAQ83001.1 - 2.9e-28 99.2 0.0 4e-28 98.7 0.0 1.2 1 0 0 1 1 1 1 Histone acetylation protein PSRP-3_Ycf65 PF04839.13 EAQ83001.1 - 0.05 13.8 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 Plastid and cyanobacterial ribosomal protein (PSRP-3 / Ycf65) SET PF00856.28 EAQ83002.1 - 2.7e-17 63.7 0.1 1e-16 61.8 0.0 1.8 2 0 0 2 2 2 1 SET domain Rubis-subs-bind PF09273.11 EAQ83002.1 - 8.8e-10 39.4 2.7 1.4e-09 38.7 0.7 2.1 2 0 0 2 2 2 1 Rubisco LSMT substrate-binding DUF2183 PF09949.9 EAQ83003.1 - 5.9e-31 106.7 0.0 1.8e-30 105.2 0.0 1.8 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2183) NDC10_II PF16787.5 EAQ83004.1 - 2.2e-46 158.4 0.0 2.6e-38 131.9 0.0 2.3 2 0 0 2 2 2 2 Centromere DNA-binding protein complex CBF3 subunit, domain 2 GCR1_C PF12550.8 EAQ83004.1 - 2.6e-18 66.1 0.2 4.9e-18 65.2 0.2 1.5 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes ImcF-related_N PF14331.6 EAQ83004.1 - 0.0024 17.3 0.6 0.0057 16.1 0.6 1.6 1 0 0 1 1 1 1 ImcF-related N-terminal domain Exo_endo_phos_2 PF14529.6 EAQ83005.1 - 6e-13 48.7 0.0 1.2e-12 47.7 0.0 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 EAQ83005.1 - 2e-06 27.5 0.2 5.7e-06 26.0 0.2 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RVT_1 PF00078.27 EAQ83005.1 - 3e-06 26.9 0.0 4.8e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HTH_psq PF05225.16 EAQ83007.1 - 0.00026 20.7 0.1 0.0005 19.8 0.1 1.4 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_Tnp_Tc3_2 PF01498.18 EAQ83008.1 - 2.4e-17 62.9 4.7 2.4e-17 62.9 4.7 2.3 3 0 0 3 3 2 1 Transposase DDE_3 PF13358.6 EAQ83008.1 - 3.8e-12 46.2 1.9 4e-12 46.1 0.2 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_29 PF13551.6 EAQ83008.1 - 2e-11 43.7 10.5 4.3e-05 23.4 0.5 3.6 3 0 0 3 3 3 2 Winged helix-turn helix HTH_32 PF13565.6 EAQ83008.1 - 5.7e-11 42.9 13.4 1.3e-09 38.5 2.3 3.2 2 1 1 3 3 3 2 Homeodomain-like domain HTH_28 PF13518.6 EAQ83008.1 - 6.2e-09 35.8 7.4 0.00058 19.9 0.1 3.7 3 0 0 3 3 3 2 Helix-turn-helix domain HTH_23 PF13384.6 EAQ83008.1 - 2.4e-07 30.3 15.3 0.00046 19.9 0.1 4.0 4 0 0 4 4 4 2 Homeodomain-like domain HTH_38 PF13936.6 EAQ83008.1 - 3.1e-05 23.6 7.2 0.062 13.1 0.0 3.6 3 0 0 3 3 3 2 Helix-turn-helix domain CENP-B_N PF04218.13 EAQ83008.1 - 7.3e-05 22.3 3.5 0.61 9.8 0.4 4.3 4 0 0 4 4 4 2 CENP-B N-terminal DNA-binding domain HTH_Tnp_ISL3 PF13542.6 EAQ83008.1 - 0.00058 19.2 19.1 0.038 13.4 0.3 4.9 5 0 0 5 5 5 2 Helix-turn-helix domain of transposase family ISL3 PAX PF00292.18 EAQ83008.1 - 0.00078 19.4 1.4 0.04 13.8 0.2 2.3 2 0 0 2 2 2 1 'Paired box' domain HTH_7 PF02796.15 EAQ83008.1 - 0.0013 18.8 0.9 0.26 11.4 0.0 3.2 3 0 0 3 3 3 1 Helix-turn-helix domain of resolvase HTH_Tnp_IS630 PF01710.16 EAQ83008.1 - 0.0023 17.9 0.4 1.2 9.2 0.1 2.5 2 0 0 2 2 2 2 Transposase MarR_2 PF12802.7 EAQ83008.1 - 0.067 13.1 0.4 0.067 13.1 0.4 3.0 3 0 0 3 3 3 0 MarR family HTH_WhiA PF02650.14 EAQ83008.1 - 0.11 12.9 0.2 0.28 11.5 0.2 1.7 1 0 0 1 1 1 0 WhiA C-terminal HTH domain GntR PF00392.21 EAQ83008.1 - 0.26 11.0 3.2 16 5.3 0.1 3.5 3 0 0 3 3 3 0 Bacterial regulatory proteins, gntR family HTH_Tnp_4 PF13613.6 EAQ83008.1 - 2.3 8.0 4.5 6.9 6.5 0.1 3.1 3 0 0 3 3 3 0 Helix-turn-helix of DDE superfamily endonuclease HTH_31 PF13560.6 EAQ83008.1 - 6.8 7.1 12.9 22 5.5 0.4 4.0 3 1 0 3 3 3 0 Helix-turn-helix domain Helicase_C PF00271.31 EAQ83009.1 - 2.6e-08 34.2 0.0 8e-08 32.6 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF5030 PF16433.5 EAQ83009.1 - 0.0093 15.3 0.0 0.025 13.9 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF5030) HTH_Tnp_Tc5 PF03221.16 EAQ83010.1 - 5.1e-16 58.5 0.1 3e-12 46.4 0.1 3.0 2 0 0 2 2 2 2 Tc5 transposase DNA-binding domain HTH_psq PF05225.16 EAQ83010.1 - 2.4e-15 56.0 0.0 1.1e-06 28.3 0.0 2.5 2 0 0 2 2 2 2 helix-turn-helix, Psq domain HTH_23 PF13384.6 EAQ83010.1 - 4.6e-06 26.3 0.6 0.029 14.2 0.0 3.5 3 0 0 3 3 3 2 Homeodomain-like domain HTH_3 PF01381.22 EAQ83010.1 - 0.0099 15.9 0.1 0.025 14.6 0.1 1.7 1 0 0 1 1 1 1 Helix-turn-helix HTH_37 PF13744.6 EAQ83010.1 - 0.05 13.6 0.1 0.16 11.9 0.1 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_28 PF13518.6 EAQ83010.1 - 0.22 11.6 2.6 20 5.4 0.0 3.8 3 0 0 3 3 3 0 Helix-turn-helix domain RVT_1 PF00078.27 EAQ83011.1 - 1.5e-09 37.7 0.0 2.7e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_1 PF03184.19 EAQ83012.1 - 0.15 11.7 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 DDE superfamily endonuclease zf-RVT PF13966.6 EAQ83013.1 - 0.025 15.3 0.0 0.067 13.9 0.0 1.7 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase Pyr_redox_2 PF07992.14 EAQ83014.1 - 2.4e-42 145.2 0.3 3.2e-42 144.8 0.3 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EAQ83014.1 - 2.8e-13 50.2 0.3 7.7e-09 36.0 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EAQ83014.1 - 1.7e-11 44.3 5.4 0.052 13.1 0.0 4.1 4 0 0 4 4 4 4 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EAQ83014.1 - 4.3e-05 23.5 3.0 0.27 11.2 0.2 3.4 2 1 1 3 3 3 3 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 EAQ83014.1 - 0.00085 19.5 0.2 1.3 9.3 0.0 2.8 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EAQ83014.1 - 0.0017 17.5 1.2 1.5 7.8 0.0 3.0 3 0 0 3 3 3 2 Lycopene cyclase protein Pyr_redox_3 PF13738.6 EAQ83014.1 - 0.0056 16.0 0.0 9.8 5.3 0.0 3.1 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Sigma70_ECF PF07638.11 EAQ83014.1 - 0.034 14.0 0.0 0.057 13.3 0.0 1.3 1 0 0 1 1 1 0 ECF sigma factor TrkA_N PF02254.18 EAQ83014.1 - 0.25 11.6 1.0 0.97 9.7 0.1 2.5 3 0 0 3 3 3 0 TrkA-N domain HI0933_like PF03486.14 EAQ83014.1 - 0.67 8.6 3.1 0.73 8.5 0.1 2.5 4 0 0 4 4 4 0 HI0933-like protein Zn_clus PF00172.18 EAQ83015.1 - 7.1e-09 35.6 11.4 1.8e-08 34.4 11.4 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EAQ83015.1 - 1.6e-06 27.4 0.1 2.6e-06 26.7 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain PALP PF00291.25 EAQ83016.1 - 2.8e-79 266.6 0.5 2.8e-79 266.6 0.5 1.6 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 EAQ83016.1 - 9.8e-39 131.0 0.0 2.3e-19 68.9 0.0 2.3 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase HIG_1_N PF04588.13 EAQ83017.1 - 2.6e-23 82.0 0.7 2.6e-23 82.0 0.7 1.9 2 0 0 2 2 2 1 Hypoxia induced protein conserved region DUF2514 PF10721.9 EAQ83017.1 - 2.7 8.0 15.4 3.1 7.8 14.9 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2514) Presenilin PF01080.17 EAQ83017.1 - 5.6 5.6 5.3 7.3 5.3 5.3 1.1 1 0 0 1 1 1 0 Presenilin TLD PF07534.16 EAQ83018.1 - 6.3e-27 94.5 0.0 2.3e-26 92.7 0.0 1.8 1 1 0 1 1 1 1 TLD DUF1773 PF08593.10 EAQ83018.1 - 8.7e-10 39.5 1.1 2.3e-09 38.1 1.1 1.7 1 0 0 1 1 1 1 Domain of unknown function RPEL PF02755.15 EAQ83019.1 - 4.5e-22 77.0 1.0 1.2e-11 43.9 0.1 2.4 2 0 0 2 2 2 2 RPEL repeat TrkH PF02386.16 EAQ83021.1 - 6.8e-77 259.0 0.0 3.9e-41 141.1 0.0 3.1 2 1 1 3 3 3 3 Cation transport protein FKBP_C PF00254.28 EAQ83021.1 - 4.4e-30 103.9 0.0 7.9e-30 103.0 0.0 1.5 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase IMS PF00817.20 EAQ83022.1 - 9.7e-44 149.0 0.0 2.7e-43 147.5 0.1 1.8 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.8 EAQ83022.1 - 2.4e-14 54.0 0.9 6e-14 52.8 0.2 1.9 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 EAQ83022.1 - 0.0014 18.8 0.0 0.0038 17.5 0.0 1.8 1 0 0 1 1 1 1 IMS family HHH motif Memo PF01875.17 EAQ83023.1 - 1.2e-65 221.3 0.0 1.5e-65 221.0 0.0 1.1 1 0 0 1 1 1 1 Memo-like protein SNARE PF05739.19 EAQ83024.1 - 4.3e-10 39.4 0.5 4.3e-10 39.4 0.5 2.6 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.25 EAQ83024.1 - 4.9e-10 39.4 18.2 4.9e-10 39.4 18.2 1.8 1 1 0 1 1 1 1 Syntaxin Syntaxin-6_N PF09177.11 EAQ83024.1 - 0.0014 19.2 10.2 0.007 16.9 2.3 2.7 2 0 0 2 2 2 1 Syntaxin 6, N-terminal DUF2951 PF11166.8 EAQ83024.1 - 0.0061 16.8 1.3 0.0061 16.8 1.3 2.8 3 1 1 4 4 3 1 Protein of unknown function (DUF2951) DUF2615 PF11027.8 EAQ83024.1 - 0.009 16.1 0.0 0.046 13.9 0.0 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF2615) DUF2207 PF09972.9 EAQ83024.1 - 0.015 14.1 1.3 0.021 13.6 0.0 1.8 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF4834 PF16118.5 EAQ83024.1 - 0.016 16.1 0.0 0.016 16.1 0.0 3.2 2 1 0 2 2 1 0 Domain of unknown function (DUF4834) Alpha_GJ PF03229.13 EAQ83024.1 - 0.029 14.9 0.8 0.079 13.5 0.8 1.7 1 0 0 1 1 1 0 Alphavirus glycoprotein J LMBR1 PF04791.16 EAQ83024.1 - 0.032 13.2 5.0 0.049 12.5 5.0 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein MCU PF04678.13 EAQ83024.1 - 0.16 12.0 16.1 0.65 10.1 3.1 2.3 1 1 1 2 2 2 0 Mitochondrial calcium uniporter PIG-P PF08510.12 EAQ83024.1 - 0.37 10.7 4.2 0.25 11.3 0.7 2.2 2 0 0 2 2 2 0 PIG-P Syntaxin_2 PF14523.6 EAQ83024.1 - 0.92 9.9 13.9 0.43 11.0 4.0 2.9 2 1 0 2 2 2 0 Syntaxin-like protein CrgA PF06781.12 EAQ83024.1 - 1.9 8.6 3.8 1 9.5 0.1 2.3 2 0 0 2 2 2 0 Cell division protein CrgA DUF948 PF06103.11 EAQ83024.1 - 3.2 8.1 7.4 2.3 8.5 1.5 3.2 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Tweety PF04906.13 EAQ83024.1 - 4.5 5.8 6.9 0.28 9.8 1.2 1.7 2 0 0 2 2 2 0 Tweety TMEM132D_C PF15706.5 EAQ83024.1 - 5.7 6.8 5.4 3 7.7 1.1 2.6 2 1 0 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term EMP24_GP25L PF01105.24 EAQ83024.1 - 5.9 6.8 9.7 1.1 9.2 1.4 2.6 2 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD DUF1053 PF06327.14 EAQ83024.1 - 6.9 7.3 10.5 0.51 10.9 1.8 2.7 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1053) zf-ANAPC11 PF12861.7 EAQ83026.1 - 1.4e-45 153.3 11.2 1.6e-45 153.0 11.2 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 EAQ83026.1 - 3.4e-22 78.5 12.0 5.1e-22 77.9 12.0 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 EAQ83026.1 - 4.3e-08 33.4 15.3 9.1e-07 29.1 15.3 2.4 1 1 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 EAQ83026.1 - 3.7e-05 23.7 10.6 0.00015 21.7 6.1 2.5 2 1 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EAQ83026.1 - 0.0001 22.1 14.2 0.0005 19.9 14.2 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EAQ83026.1 - 0.00038 20.5 3.7 0.00038 20.5 3.7 2.3 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 EAQ83026.1 - 0.00063 19.5 5.0 0.00093 19.0 5.0 1.3 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.6 EAQ83026.1 - 0.0054 16.5 3.0 0.0054 16.5 3.0 2.4 1 1 1 2 2 2 1 RING/Ubox like zinc-binding domain zf-C3HC4_2 PF13923.6 EAQ83026.1 - 0.008 16.0 18.3 0.022 14.6 14.3 2.7 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EAQ83026.1 - 0.01 15.7 13.5 0.018 14.9 8.8 2.2 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 EAQ83026.1 - 0.011 15.3 11.8 0.13 11.9 11.8 2.1 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 EAQ83026.1 - 0.018 15.2 16.6 0.42 10.8 16.6 3.1 1 1 0 1 1 1 0 FANCL C-terminal domain VioE PF18234.1 EAQ83026.1 - 0.068 13.3 0.2 0.082 13.0 0.2 1.0 1 0 0 1 1 1 0 Violacein biosynthetic enzyme VioE Elf1 PF05129.13 EAQ83026.1 - 0.081 13.0 3.9 0.099 12.7 0.0 2.3 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like YacG PF03884.14 EAQ83026.1 - 0.22 11.3 0.5 0.22 11.3 0.5 2.7 2 1 0 2 2 2 0 DNA gyrase inhibitor YacG UBZ_FAAP20 PF15750.5 EAQ83026.1 - 0.31 11.0 5.0 2.4 8.2 0.1 2.9 2 1 1 3 3 3 0 Ubiquitin-binding zinc-finger zf-RING_5 PF14634.6 EAQ83026.1 - 0.32 11.0 17.6 9.2 6.3 18.0 2.8 1 1 1 2 2 2 0 zinc-RING finger domain TerY_C PF15616.6 EAQ83026.1 - 0.4 10.8 5.3 0.37 10.9 4.4 1.3 1 1 0 1 1 1 0 TerY-C metal binding domain Rad50_zn_hook PF04423.14 EAQ83026.1 - 1.2 9.1 0.0 1.2 9.1 0.0 2.8 2 1 1 3 3 3 0 Rad50 zinc hook motif zf-RING_11 PF17123.5 EAQ83026.1 - 1.2 8.9 13.1 3.1 7.6 10.6 2.7 2 1 0 2 2 2 0 RING-like zinc finger Zn-C2H2_12 PF18112.1 EAQ83026.1 - 1.4 9.4 0.1 1.4 9.4 0.1 3.4 4 1 0 4 4 4 0 Autophagy receptor zinc finger-C2H2 domain Prok-RING_4 PF14447.6 EAQ83026.1 - 1.5 8.8 14.7 5.6 6.9 11.0 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 RINGv PF12906.7 EAQ83026.1 - 2.1 8.6 13.0 2.6 8.2 11.3 2.1 1 1 1 2 2 2 0 RING-variant domain zf-RING-like PF08746.11 EAQ83026.1 - 3.3 8.1 13.4 23 5.4 13.4 2.2 1 1 0 1 1 1 0 RING-like domain zf-HC5HC2H_2 PF13832.6 EAQ83026.1 - 4.7 7.4 10.6 2.6 8.2 5.7 2.2 1 1 1 2 2 2 0 PHD-zinc-finger like domain DUF393 PF04134.12 EAQ83026.1 - 5.4 8.4 6.5 30 6.0 0.1 2.7 3 0 0 3 3 2 0 Protein of unknown function, DUF393 Abhydrolase_1 PF00561.20 EAQ83027.1 - 2.1e-25 89.9 0.1 8.4e-22 78.0 0.0 2.0 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EAQ83027.1 - 5.4e-16 59.9 2.7 6.6e-16 59.6 2.7 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EAQ83027.1 - 5.1e-05 22.7 0.0 0.00015 21.1 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 GMC_oxred_N PF00732.19 EAQ83028.1 - 1.6e-59 201.7 0.0 2.1e-59 201.4 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EAQ83028.1 - 8.7e-31 107.4 0.0 1.7e-30 106.4 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 EAQ83028.1 - 0.00046 20.4 0.0 0.0015 18.8 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EAQ83028.1 - 0.0019 17.3 0.1 0.0035 16.5 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 EAQ83028.1 - 0.0024 17.5 0.4 0.0078 15.8 0.2 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EAQ83028.1 - 0.0026 16.9 0.0 0.12 11.5 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 EAQ83028.1 - 0.02 13.6 0.0 3 6.5 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.17 EAQ83028.1 - 0.03 13.6 0.0 0.058 12.6 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 EAQ83028.1 - 0.073 12.3 0.5 11 5.2 0.3 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Glyco_hydro_18 PF00704.28 EAQ83029.1 - 3.8e-40 138.5 0.0 4.6e-40 138.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 ANAPC4_WD40 PF12894.7 EAQ83030.1 - 0.00021 21.5 0.0 0.023 15.0 0.0 2.6 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EAQ83030.1 - 0.0088 16.9 3.3 1.5 9.8 0.0 4.2 5 0 0 5 5 5 1 WD domain, G-beta repeat PQQ_3 PF13570.6 EAQ83030.1 - 0.028 14.9 2.3 21 5.7 1.4 3.5 2 1 0 2 2 2 0 PQQ-like domain Tankyrase_bdg_C PF15327.6 EAQ83030.1 - 0.053 14.0 1.2 0.088 13.3 1.2 1.3 1 0 0 1 1 1 0 Tankyrase binding protein C terminal domain DUF2835 PF11197.8 EAQ83030.1 - 0.24 11.3 0.2 0.72 9.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2835) Inositol_P PF00459.25 EAQ83031.1 - 1.7e-68 231.1 0.1 1.7e-48 165.5 0.0 2.0 1 1 1 2 2 2 2 Inositol monophosphatase family RVT_2 PF07727.14 EAQ83032.1 - 7.4e-16 58.5 0.0 2.1e-15 57.1 0.0 1.8 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotran_gag_2 PF14223.6 EAQ83033.1 - 0.0066 16.1 0.6 0.0066 16.1 0.6 1.8 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type Peptidase_U49 PF10463.9 EAQ83033.1 - 0.0098 15.7 0.3 0.02 14.7 0.3 1.4 1 0 0 1 1 1 1 Peptidase U49 gp45-slide_C PF09116.10 EAQ83033.1 - 0.092 12.8 0.2 0.18 11.9 0.2 1.5 1 0 0 1 1 1 0 gp45 sliding clamp, C terminal PolC_DP2 PF03833.13 EAQ83033.1 - 0.14 10.0 3.9 0.2 9.5 3.9 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zinc_ribbon_15 PF17032.5 EAQ83033.1 - 0.28 12.0 3.8 0.67 10.8 3.8 1.6 1 0 0 1 1 1 0 zinc-ribbon family DUF3446 PF11928.8 EAQ83033.1 - 8.3 6.8 14.7 3.7 7.9 8.6 2.3 2 0 0 2 2 2 0 Early growth response N-terminal domain AP_endonuc_2 PF01261.24 EAQ83034.1 - 6.9e-30 104.1 0.0 8.4e-30 103.8 0.0 1.0 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Carot_N PF09150.10 EAQ83034.1 - 0.013 15.4 0.0 0.023 14.6 0.0 1.4 1 0 0 1 1 1 0 Orange carotenoid protein, N-terminal Shikimate_dh_N PF08501.11 EAQ83035.1 - 3.3e-10 40.1 0.0 1.2e-09 38.3 0.0 1.9 2 0 0 2 2 2 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 EAQ83035.1 - 2e-05 24.3 0.1 7.7e-05 22.4 0.0 2.1 2 0 0 2 2 2 1 Shikimate 5'-dehydrogenase C-terminal domain Sugar_tr PF00083.24 EAQ83036.1 - 3e-131 438.4 21.3 3.4e-131 438.2 21.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EAQ83036.1 - 2.6e-22 79.3 36.6 2.6e-22 79.3 36.6 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Shikimate_dh_N PF08501.11 EAQ83037.1 - 2.6e-21 75.7 0.1 6.6e-21 74.4 0.1 1.7 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain DHquinase_I PF01487.15 EAQ83037.1 - 9.3e-18 65.3 0.0 1.7e-17 64.4 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase SDH_C PF18317.1 EAQ83037.1 - 4.4e-10 39.1 0.3 2e-09 37.0 0.2 2.1 2 0 0 2 2 2 1 Shikimate 5'-dehydrogenase C-terminal domain SKI PF01202.22 EAQ83037.1 - 6.4e-10 39.4 0.0 1.2e-09 38.5 0.0 1.4 1 0 0 1 1 1 1 Shikimate kinase Shikimate_DH PF01488.20 EAQ83037.1 - 1.9e-06 28.0 0.1 3.7e-06 27.0 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Zeta_toxin PF06414.12 EAQ83037.1 - 0.024 13.9 0.0 0.051 12.9 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.6 EAQ83037.1 - 0.059 13.9 0.0 0.11 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Fungal_trans PF04082.18 EAQ83038.1 - 0.0016 17.5 0.0 0.0029 16.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Gpr1_Fun34_YaaH PF01184.19 EAQ83039.1 - 6.6e-88 293.7 15.1 7.8e-88 293.5 15.1 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Ribosomal_S5 PF00333.20 EAQ83040.1 - 2.4e-27 94.7 1.0 5.3e-27 93.6 1.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 EAQ83040.1 - 4.7e-22 77.2 0.8 7.4e-22 76.6 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein S5, C-terminal domain FoP_duplication PF13865.6 EAQ83040.1 - 4.7 7.8 19.3 12 6.5 19.3 1.7 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 MARVEL PF01284.23 EAQ83041.1 - 9.2e-12 45.2 17.8 1.1e-11 45.0 17.8 1.1 1 0 0 1 1 1 1 Membrane-associating domain Abhydrolase_1 PF00561.20 EAQ83042.1 - 8.9e-18 64.9 0.3 1.2e-14 54.7 0.1 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 EAQ83042.1 - 1.4e-15 57.2 0.0 3.2e-15 56.1 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein NIBRIN_BRCT_II PF16508.5 EAQ83043.1 - 2e-39 134.6 0.0 5.5e-39 133.2 0.0 1.8 1 0 0 1 1 1 1 Second BRCT domain on Nijmegen syndrome breakage protein FHA PF00498.26 EAQ83043.1 - 1.5e-05 25.3 0.1 3.1e-05 24.2 0.1 1.5 1 0 0 1 1 1 1 FHA domain RTT107_BRCT_5 PF16770.5 EAQ83043.1 - 0.0015 18.4 0.0 0.0038 17.1 0.0 1.6 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT PF00533.26 EAQ83043.1 - 0.007 16.7 0.0 0.037 14.4 0.0 2.0 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Cyt-b5 PF00173.28 EAQ83044.1 - 2.5e-10 40.4 0.0 3.7e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DnaJ-X PF14308.6 EAQ83046.1 - 3.3e-76 255.4 1.0 3.3e-76 255.4 1.0 2.7 3 0 0 3 3 3 1 X-domain of DnaJ-containing DnaJ PF00226.31 EAQ83046.1 - 2.4e-26 91.6 0.9 5.7e-26 90.4 0.9 1.7 1 0 0 1 1 1 1 DnaJ domain PA-IL PF07828.12 EAQ83046.1 - 0.0076 16.2 0.0 0.015 15.3 0.0 1.4 1 0 0 1 1 1 1 PA-IL-like protein SUZ PF12752.7 EAQ83046.1 - 0.0099 16.6 3.6 0.053 14.3 3.6 2.3 1 0 0 1 1 1 1 SUZ domain SelP_N PF04592.14 EAQ83046.1 - 0.31 10.4 14.1 0.036 13.5 9.3 1.9 2 0 0 2 2 2 0 Selenoprotein P, N terminal region NicO PF03824.16 EAQ83046.1 - 2.2 7.6 3.6 4.1 6.7 3.6 1.4 1 0 0 1 1 1 0 High-affinity nickel-transport protein RmlD_sub_bind PF04321.17 EAQ83047.1 - 4.9e-15 55.4 0.0 1.7e-14 53.6 0.0 1.8 1 1 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 EAQ83047.1 - 8.6e-14 51.6 0.0 1.5e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EAQ83047.1 - 0.0001 21.5 0.0 0.00021 20.5 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 EAQ83047.1 - 0.00023 20.7 0.0 0.00061 19.3 0.0 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase SQS_PSY PF00494.19 EAQ83048.1 - 4.1e-36 124.8 0.0 7e-36 124.1 0.0 1.4 2 0 0 2 2 2 1 Squalene/phytoene synthase Gram_pos_anchor PF00746.21 EAQ83048.1 - 0.71 9.9 1.8 1.2 9.2 1.8 1.3 1 0 0 1 1 1 0 LPXTG cell wall anchor motif Peptidase_S8 PF00082.22 EAQ83049.1 - 5.7e-29 101.3 11.8 1e-28 100.5 11.8 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EAQ83049.1 - 0.028 15.1 0.3 0.045 14.4 0.3 1.3 1 0 0 1 1 1 0 Peptidase inhibitor I9 Alpha_GJ PF03229.13 EAQ83051.1 - 0.09 13.3 4.7 0.27 11.8 4.7 1.8 1 0 0 1 1 1 0 Alphavirus glycoprotein J MadL PF03817.13 EAQ83051.1 - 0.095 12.7 0.1 0.19 11.8 0.1 1.4 1 0 0 1 1 1 0 Malonate transporter MadL subunit F-box-like PF12937.7 EAQ83052.1 - 0.00022 21.0 0.0 0.0014 18.5 0.0 2.3 2 1 0 2 2 2 1 F-box-like F-box PF00646.33 EAQ83052.1 - 0.24 11.3 1.3 25 4.9 0.0 3.7 4 0 0 4 4 4 0 F-box domain Mannosyl_trans PF05007.13 EAQ83053.1 - 1.8e-48 165.6 10.5 9.4e-32 110.9 6.8 2.2 1 1 1 2 2 2 2 Mannosyltransferase (PIG-M) PIG-U PF06728.13 EAQ83053.1 - 1.8e-11 43.8 0.1 1.8e-11 43.8 0.1 2.0 1 1 1 2 2 2 1 GPI transamidase subunit PIG-U Translin PF01997.16 EAQ83054.1 - 3.6e-61 206.7 0.0 4.2e-61 206.5 0.0 1.0 1 0 0 1 1 1 1 Translin family EF1_GNE PF00736.19 EAQ83055.1 - 9.6e-33 112.2 2.8 1.7e-32 111.4 2.8 1.4 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 EAQ83055.1 - 1.2e-12 48.0 6.2 1.2e-12 48.0 6.2 2.5 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_3 PF14497.6 EAQ83055.1 - 0.0096 16.1 0.6 0.028 14.6 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain DUF211 PF02680.14 EAQ83055.1 - 0.03 14.5 1.2 0.055 13.6 0.7 1.6 1 1 0 1 1 1 0 Uncharacterized ArCR, COG1888 UBA2_C PF16195.5 EAQ83055.1 - 0.087 13.5 3.7 0.15 12.8 3.7 1.3 1 0 0 1 1 1 0 SUMO-activating enzyme subunit 2 C-terminus GST_C PF00043.25 EAQ83055.1 - 0.17 12.1 0.3 0.17 12.1 0.3 2.3 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain CTP_transf_like PF01467.26 EAQ83057.1 - 1.8e-05 25.0 0.0 3.8e-05 23.9 0.0 1.6 1 1 0 1 1 1 1 Cytidylyltransferase-like Amidase PF01425.21 EAQ83058.1 - 2.4e-44 152.1 0.1 1.8e-43 149.2 0.1 2.3 1 1 1 2 2 2 1 Amidase GMC_oxred_N PF00732.19 EAQ83060.1 - 3.8e-58 197.2 0.0 4.8e-58 196.9 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EAQ83060.1 - 6.3e-32 111.1 0.0 9.9e-32 110.4 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 EAQ83060.1 - 3.4e-06 26.5 0.1 0.00022 20.5 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EAQ83060.1 - 3.6e-05 23.0 1.4 0.0043 16.2 0.5 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 EAQ83060.1 - 0.00027 20.1 0.2 0.00045 19.4 0.2 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 EAQ83060.1 - 0.00059 20.0 0.4 0.0014 18.9 0.4 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EAQ83060.1 - 0.00098 18.5 0.3 1 8.6 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EAQ83060.1 - 0.003 16.3 0.9 0.04 12.6 0.1 2.0 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.24 EAQ83060.1 - 0.0053 16.4 4.9 0.0053 16.4 0.5 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.17 EAQ83060.1 - 0.042 13.1 0.6 0.16 11.2 0.1 2.1 2 1 1 3 3 3 0 Thi4 family TrkA_N PF02254.18 EAQ83060.1 - 0.1 12.9 0.1 0.23 11.7 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain Trp_halogenase PF04820.14 EAQ83060.1 - 0.26 10.1 0.2 0.39 9.5 0.2 1.2 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_9 PF13454.6 EAQ83060.1 - 0.31 11.0 1.9 0.42 10.6 0.2 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding Helitron_like_N PF14214.6 EAQ83061.1 - 6.4e-37 127.6 0.0 6.4e-37 127.6 0.0 2.5 2 1 0 3 3 3 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.14 EAQ83061.1 - 2.6e-18 66.4 0.1 4.8e-18 65.5 0.1 1.3 1 0 0 1 1 1 1 PIF1-like helicase AAA_19 PF13245.6 EAQ83061.1 - 0.0026 18.1 0.0 0.0067 16.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 EAQ83061.1 - 0.023 14.5 0.0 0.068 13.0 0.0 1.9 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Patatin PF01734.22 EAQ83062.1 - 0.013 15.6 0.2 0.02 15.0 0.2 1.3 1 0 0 1 1 1 0 Patatin-like phospholipase PIF1 PF05970.14 EAQ83063.1 - 2.1e-06 27.2 0.0 3e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase Amidohydro_2 PF04909.14 EAQ83064.1 - 6.9e-18 65.4 0.6 1.4e-11 44.7 0.0 2.1 2 0 0 2 2 2 2 Amidohydrolase DED PF01335.21 EAQ83064.1 - 0.099 13.0 0.0 0.15 12.4 0.0 1.3 1 0 0 1 1 1 0 Death effector domain Ribosomal_L36 PF00444.18 EAQ83065.1 - 4.1e-18 65.3 6.2 9.2e-18 64.2 6.2 1.6 1 1 0 1 1 1 1 Ribosomal protein L36 Dynamin_N PF00350.23 EAQ83066.1 - 0.00061 19.9 0.0 0.0012 18.9 0.0 1.6 2 0 0 2 2 2 1 Dynamin family ABC_tran PF00005.27 EAQ83066.1 - 0.00095 19.7 0.0 0.002 18.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 EAQ83066.1 - 0.0017 18.3 0.0 0.0031 17.4 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 EAQ83066.1 - 0.0024 17.9 0.0 0.0057 16.7 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase IIGP PF05049.13 EAQ83066.1 - 0.0046 16.1 0.0 0.0074 15.4 0.0 1.2 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) AAA_16 PF13191.6 EAQ83066.1 - 0.0069 16.8 0.0 0.022 15.2 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain Roc PF08477.13 EAQ83066.1 - 0.14 12.3 0.1 1.4 9.2 0.0 2.2 1 1 1 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Septin PF00735.18 EAQ83066.1 - 0.17 11.1 0.0 0.28 10.4 0.0 1.3 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 EAQ83066.1 - 0.25 10.7 0.0 0.41 9.9 0.0 1.4 1 0 0 1 1 1 0 AIG1 family CW_binding_1 PF01473.20 EAQ83069.1 - 5.3e-05 23.3 27.8 0.16 12.3 4.0 4.0 3 0 0 3 3 3 3 Putative cell wall binding repeat Ras PF00071.22 EAQ83071.1 - 0.025 14.2 0.0 0.033 13.8 0.0 1.1 1 0 0 1 1 1 0 Ras family APH PF01636.23 EAQ83072.1 - 0.003 17.5 0.1 0.0032 17.4 0.1 1.0 1 0 0 1 1 1 1 Phosphotransferase enzyme family zf-primase PF09329.11 EAQ83072.1 - 0.029 14.2 0.2 0.039 13.8 0.2 1.2 1 0 0 1 1 1 0 Primase zinc finger Choline_kinase PF01633.20 EAQ83072.1 - 0.11 12.1 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 Choline/ethanolamine kinase PLAC8 PF04749.17 EAQ83075.1 - 2.8e-12 47.5 5.5 3.6e-12 47.2 5.5 1.1 1 0 0 1 1 1 1 PLAC8 family p450 PF00067.22 EAQ83076.1 - 7.7e-22 77.7 0.0 1.2e-10 40.7 0.0 2.9 3 0 0 3 3 3 2 Cytochrome P450 PIG-S PF10510.9 EAQ83077.1 - 1.1e-169 565.6 0.1 1.2e-169 565.4 0.1 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein AMP-binding PF00501.28 EAQ83078.1 - 1.3e-71 241.5 0.0 1.7e-71 241.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EAQ83078.1 - 3.5e-08 34.3 0.3 7.6e-08 33.2 0.3 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AhpC-TSA PF00578.21 EAQ83079.1 - 2.7e-29 101.6 0.0 3.6e-29 101.2 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.9 EAQ83079.1 - 1.5e-10 40.7 0.2 2.9e-10 39.8 0.2 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.10 EAQ83079.1 - 4e-10 39.6 0.0 5.3e-10 39.2 0.0 1.1 1 0 0 1 1 1 1 Redoxin BTB PF00651.31 EAQ83080.1 - 0.019 15.2 0.0 0.19 12.0 0.0 2.1 2 0 0 2 2 2 0 BTB/POZ domain MFS_1 PF07690.16 EAQ83081.1 - 2e-16 59.9 27.8 3.4e-08 32.8 4.7 3.2 3 0 0 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.24 EAQ83081.1 - 0.00037 19.5 5.8 0.033 13.1 3.3 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter Antimicrobial24 PF16049.5 EAQ83081.1 - 1.1 9.3 10.5 0.95 9.5 2.0 2.5 2 0 0 2 2 2 0 Frog antimicrobial peptide RebB PF11747.8 EAQ83081.1 - 2.1 8.5 4.1 0.93 9.6 0.2 2.4 3 0 0 3 3 3 0 Killing trait Sulfatase PF00884.23 EAQ83082.1 - 2.6e-56 191.3 0.0 3.8e-56 190.7 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 EAQ83082.1 - 0.026 14.1 0.3 1.8 8.1 0.1 2.2 2 0 0 2 2 2 0 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4976 PF16347.5 EAQ83082.1 - 0.055 13.7 0.2 0.14 12.4 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4976) Tautomerase_3 PF14832.6 EAQ83083.1 - 3.3e-47 160.2 0.1 3.6e-47 160.0 0.1 1.0 1 0 0 1 1 1 1 Putative oxalocrotonate tautomerase enzyme MULE PF10551.9 EAQ83084.1 - 7.2e-09 36.0 0.0 1.5e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.18 EAQ83084.1 - 0.00045 19.2 0.1 0.001 18.0 0.1 1.5 1 0 0 1 1 1 1 Transposase, Mutator family F-box PF00646.33 EAQ83084.1 - 0.00054 19.8 0.0 0.00092 19.0 0.0 1.4 1 0 0 1 1 1 1 F-box domain FAR1 PF03101.15 EAQ83084.1 - 0.0015 19.2 0.1 0.0031 18.2 0.1 1.6 1 0 0 1 1 1 1 FAR1 DNA-binding domain F-box-like PF12937.7 EAQ83084.1 - 0.0029 17.5 0.0 0.0057 16.5 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 EAQ83084.1 - 0.008 16.0 0.0 0.022 14.6 0.0 1.7 1 0 0 1 1 1 1 F-box AMP-binding PF00501.28 EAQ83085.1 - 3.8e-98 328.9 0.1 4.7e-98 328.5 0.1 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EAQ83085.1 - 3.5e-13 50.3 0.3 9.9e-13 48.9 0.3 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Pyr_redox_2 PF07992.14 EAQ83086.1 - 1e-24 87.3 0.0 2e-24 86.4 0.0 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EAQ83086.1 - 2e-13 50.7 0.9 7.6e-12 45.6 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EAQ83086.1 - 0.00015 21.0 0.1 0.00039 19.7 0.1 1.6 1 1 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.12 EAQ83086.1 - 0.0013 17.9 0.1 0.002 17.2 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Trp_halogenase PF04820.14 EAQ83086.1 - 0.037 12.9 0.0 0.47 9.2 0.0 2.2 2 0 0 2 2 2 0 Tryptophan halogenase Pyr_redox_3 PF13738.6 EAQ83086.1 - 0.087 12.1 0.0 0.18 11.0 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EAQ83086.1 - 0.098 12.2 0.8 0.22 11.1 0.1 1.9 3 0 0 3 3 3 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EAQ83086.1 - 0.12 12.4 0.4 7.8 6.5 0.1 2.6 3 0 0 3 3 3 0 FAD-NAD(P)-binding HI0933_like PF03486.14 EAQ83086.1 - 0.18 10.5 0.3 0.57 8.8 0.1 1.8 2 0 0 2 2 2 0 HI0933-like protein PIF1 PF05970.14 EAQ83087.1 - 9.8e-16 57.9 0.0 1.5e-15 57.3 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase UvrD_C_2 PF13538.6 EAQ83087.1 - 0.00015 21.5 0.0 0.00031 20.5 0.0 1.5 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.14 EAQ83087.1 - 0.00031 18.8 0.0 0.0012 16.9 0.0 1.7 2 0 0 2 2 2 1 Helicase Viral_helicase1 PF01443.18 EAQ83087.1 - 0.32 10.7 0.6 3 7.5 0.0 2.5 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase RVT_1 PF00078.27 EAQ83089.1 - 4e-24 85.4 0.0 2.1e-23 83.0 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 EAQ83089.1 - 0.11 13.2 0.0 0.5 11.1 0.0 2.2 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase adh_short PF00106.25 EAQ83091.1 - 7.4e-17 61.4 0.0 6.7e-16 58.3 0.0 2.2 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EAQ83091.1 - 2.4e-14 53.5 0.1 1.8e-10 40.8 0.0 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase DUF3336 PF11815.8 EAQ83092.1 - 1.2e-33 115.7 0.2 2.1e-33 115.0 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 EAQ83092.1 - 9.7e-20 71.6 0.0 1.9e-19 70.7 0.0 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase Gemini_AL1_M PF08283.11 EAQ83092.1 - 0.1 12.7 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 Geminivirus rep protein central domain Peptidase_S9 PF00326.21 EAQ83093.1 - 0.18 11.2 0.0 0.32 10.4 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 EAQ83094.1 - 9.3e-13 48.5 0.0 1.3e-12 48.0 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold 3D PF06725.11 EAQ83095.1 - 0.029 14.6 0.1 0.045 14.0 0.1 1.3 1 0 0 1 1 1 0 3D domain DUF3395 PF11875.8 EAQ83095.1 - 0.17 11.8 0.0 0.28 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3395) CorA PF01544.18 EAQ83096.1 - 0.016 14.5 8.4 0.03 13.7 8.4 1.6 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein ARTD15_N PF18084.1 EAQ83096.1 - 0.034 14.4 0.1 0.094 13.0 0.1 1.8 1 1 0 1 1 1 0 ARTD15 N-terminal domain DUF1279 PF06916.13 EAQ83096.1 - 0.1 13.1 0.8 0.2 12.3 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1279) DUF3445 PF11927.8 EAQ83097.1 - 3.9e-43 147.7 0.0 5.8e-43 147.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Tannase PF07519.11 EAQ83099.1 - 7.6e-60 203.1 0.0 1.5e-53 182.4 0.0 2.1 1 1 1 2 2 2 2 Tannase and feruloyl esterase Sugar_tr PF00083.24 EAQ83100.1 - 1.5e-91 307.5 22.7 1.8e-91 307.3 22.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EAQ83100.1 - 6.2e-14 51.7 46.3 4.1e-07 29.3 14.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Crystall PF00030.19 EAQ83101.1 - 0.002 18.3 0.6 0.0042 17.3 0.6 1.6 1 1 0 1 1 1 1 Beta/Gamma crystallin SET PF00856.28 EAQ83102.1 - 1.7e-12 48.0 0.1 4.5e-11 43.4 0.1 2.3 1 1 0 1 1 1 1 SET domain SAF PF08666.12 EAQ83102.1 - 0.083 13.5 0.1 3.6 8.3 0.0 2.3 2 0 0 2 2 2 0 SAF domain HET PF06985.11 EAQ83106.1 - 0.2 12.0 0.3 5.2 7.4 0.0 2.4 1 1 1 2 2 2 0 Heterokaryon incompatibility protein (HET) IU_nuc_hydro PF01156.19 EAQ83107.1 - 9.5e-18 64.8 0.0 1.2e-17 64.4 0.0 1.1 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Cyclin PF08613.11 EAQ83108.1 - 1.6e-42 145.6 0.0 1.6e-24 87.1 0.0 2.6 2 0 0 2 2 2 2 Cyclin Proteasome PF00227.26 EAQ83110.1 - 2.9e-48 163.9 0.1 3.3e-48 163.7 0.1 1.0 1 0 0 1 1 1 1 Proteasome subunit APH PF01636.23 EAQ83112.1 - 0.00024 21.1 0.6 0.19 11.6 0.1 2.2 2 0 0 2 2 2 2 Phosphotransferase enzyme family SET PF00856.28 EAQ83113.1 - 9.5e-14 52.1 0.1 3.4e-13 50.3 0.1 1.9 1 1 0 1 1 1 1 SET domain Terpene_synth PF01397.21 EAQ83113.1 - 0.089 12.5 0.1 0.16 11.6 0.1 1.4 1 0 0 1 1 1 0 Terpene synthase, N-terminal domain Pkinase PF00069.25 EAQ83114.1 - 2.4e-52 177.9 0.1 1.6e-50 172.0 0.1 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ83114.1 - 5.3e-30 104.6 0.0 4.6e-24 85.1 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EAQ83114.1 - 5.8e-07 29.1 0.0 8.4e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EAQ83114.1 - 2e-05 23.7 0.0 3.6e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EAQ83114.1 - 0.062 13.2 0.8 0.21 11.5 0.1 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family Ferlin_C PF16165.5 EAQ83114.1 - 0.091 12.7 0.5 0.18 11.7 0.5 1.4 1 0 0 1 1 1 0 Ferlin C-terminus C2 PF00168.30 EAQ83115.1 - 4.4e-11 43.0 0.0 7.6e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 C2 domain TRAPPC10 PF12584.8 EAQ83116.1 - 1.3e-20 73.7 0.0 3.3e-20 72.4 0.0 1.7 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 IF-2B PF01008.17 EAQ83118.1 - 1.6e-71 240.9 0.7 1.8e-71 240.6 0.7 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family Peptidase_M20 PF01546.28 EAQ83119.1 - 6.2e-12 45.6 0.0 1.1e-11 44.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EAQ83119.1 - 4.1e-08 33.1 0.1 9.8e-08 31.9 0.1 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EAQ83119.1 - 0.022 14.5 0.0 0.037 13.7 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M28 Prenyltrans PF00432.21 EAQ83120.1 - 6.5e-20 70.6 11.3 1.2e-10 41.0 0.2 4.9 5 1 0 5 5 5 3 Prenyltransferase and squalene oxidase repeat TED_complement PF07678.14 EAQ83120.1 - 0.063 12.3 0.0 2.2 7.2 0.0 2.3 2 0 0 2 2 2 0 A-macroglobulin TED domain Ilm1 PF10311.9 EAQ83121.1 - 5e-45 153.1 0.0 3.8e-29 101.5 0.0 2.0 1 1 1 2 2 2 2 Increased loss of mitochondrial DNA protein 1 SVM_signal PF12113.8 EAQ83121.1 - 0.038 13.9 0.7 0.079 12.9 0.7 1.5 1 0 0 1 1 1 0 SVM protein signal sequence NatB_MDM20 PF09797.9 EAQ83122.1 - 4.4e-78 262.9 0.0 1.7e-77 260.9 0.0 1.7 2 0 0 2 2 2 1 N-acetyltransferase B complex (NatB) non catalytic subunit CHCH PF06747.13 EAQ83122.1 - 3.9e-05 23.7 1.2 8.6e-05 22.6 1.2 1.6 1 0 0 1 1 1 1 CHCH domain MTCP1 PF08991.10 EAQ83122.1 - 0.19 11.9 2.0 0.51 10.6 2.0 1.7 1 0 0 1 1 1 0 Mature-T-Cell Proliferation I type Striatin PF08232.12 EAQ83123.1 - 0.002 18.7 0.6 0.004 17.8 0.6 1.5 1 0 0 1 1 1 1 Striatin family Glyco_hydro_76 PF03663.14 EAQ83124.1 - 7.9e-119 397.4 5.9 4.2e-67 227.2 4.8 2.0 2 0 0 2 2 2 2 Glycosyl hydrolase family 76 WDCP PF15390.6 EAQ83125.1 - 5.8 5.2 5.5 7.5 4.8 5.5 1.1 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family Zn_clus PF00172.18 EAQ83126.1 - 2.9e-07 30.5 8.9 5.6e-07 29.6 8.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EAQ83126.1 - 0.00033 19.8 0.0 0.0009 18.3 0.0 1.5 1 1 1 2 2 2 1 Fungal specific transcription factor domain DUF604 PF04646.12 EAQ83127.1 - 3.2e-05 23.5 0.0 0.0026 17.2 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function, DUF604 RabGAP-TBC PF00566.18 EAQ83128.1 - 5.7e-30 104.6 0.0 1.1e-29 103.6 0.0 1.5 2 0 0 2 2 2 1 Rab-GTPase-TBC domain SBE2 PF17076.5 EAQ83128.1 - 7.3e-07 27.8 0.5 7.3e-07 27.8 0.5 1.5 1 1 0 1 1 1 1 SBE2, cell-wall formation DUF802 PF05650.11 EAQ83128.1 - 0.51 10.9 3.6 1.8 9.1 3.6 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF802) CVNH PF08881.10 EAQ83129.1 - 5e-20 72.1 0.9 6e-20 71.8 0.9 1.1 1 0 0 1 1 1 1 CVNH domain FA_desaturase PF00487.24 EAQ83131.1 - 9.4e-14 51.9 13.1 2e-13 50.8 13.1 1.6 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 EAQ83131.1 - 2.4e-08 34.3 0.0 1.2e-07 32.0 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3474) eIF2A PF08662.11 EAQ83133.1 - 5.4e-38 130.8 3.2 8.7e-36 123.6 0.2 4.0 2 2 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.22 EAQ83133.1 - 0.00034 20.4 0.0 0.00078 19.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MnmE_helical PF12631.7 EAQ83133.1 - 0.09 12.9 0.0 0.089 13.0 0.0 1.4 1 1 0 1 1 1 0 MnmE helical domain WD40 PF00400.32 EAQ83133.1 - 0.52 11.3 2.7 66 4.6 0.0 4.5 5 0 0 5 5 5 0 WD domain, G-beta repeat Cpn60_TCP1 PF00118.24 EAQ83134.1 - 3.2e-143 477.9 11.4 3.7e-143 477.7 11.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family CRM1_repeat PF18777.1 EAQ83134.1 - 0.098 12.2 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Chromosome region maintenance or exportin repeat DUF1104 PF06518.11 EAQ83134.1 - 2.8 8.4 5.7 9.3 6.7 3.4 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1104) Glyco_hydro_61 PF03443.14 EAQ83135.1 - 2.6e-36 125.5 0.0 3e-36 125.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 TPR_12 PF13424.6 EAQ83136.1 - 5.7e-93 305.3 34.6 2.2e-20 72.7 0.1 8.0 5 3 4 9 9 8 8 Tetratricopeptide repeat TPR_10 PF13374.6 EAQ83136.1 - 1.7e-86 282.0 14.6 1e-12 47.5 0.0 10.1 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_1 PF00515.28 EAQ83136.1 - 2.2e-47 157.0 28.9 1.2e-06 28.1 0.6 9.6 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_7 PF13176.6 EAQ83136.1 - 1.2e-42 140.8 24.0 1.5e-05 24.6 0.2 10.2 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_8 PF13181.6 EAQ83136.1 - 3.3e-36 120.4 23.9 4.3e-05 23.4 0.2 9.4 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_2 PF07719.17 EAQ83136.1 - 1.1e-32 109.5 33.3 6.8e-06 25.8 1.0 9.9 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_14 PF13428.6 EAQ83136.1 - 1.4e-23 81.6 18.0 0.012 16.4 0.4 10.6 7 3 3 10 10 10 5 Tetratricopeptide repeat TPR_MalT PF17874.1 EAQ83136.1 - 6.3e-23 81.7 6.0 1.7e-12 47.4 2.9 3.9 1 1 1 3 3 3 3 MalT-like TPR region TPR_19 PF14559.6 EAQ83136.1 - 3.9e-22 78.5 15.3 2.2e-05 24.9 2.1 6.7 4 1 3 7 7 7 5 Tetratricopeptide repeat TPR_16 PF13432.6 EAQ83136.1 - 1.4e-21 76.8 28.1 2.5e-05 24.8 0.7 9.1 8 2 0 8 8 8 4 Tetratricopeptide repeat TPR_4 PF07721.14 EAQ83136.1 - 4.4e-16 57.8 0.0 0.058 14.0 0.1 8.7 9 0 0 9 9 7 3 Tetratricopeptide repeat TPR_17 PF13431.6 EAQ83136.1 - 5e-13 48.4 12.1 0.046 14.1 0.0 9.6 8 1 0 8 8 8 3 Tetratricopeptide repeat ANAPC3 PF12895.7 EAQ83136.1 - 6.4e-10 39.1 5.6 0.0034 17.6 0.2 5.2 3 1 2 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.20 EAQ83136.1 - 1.9e-08 34.0 8.2 7.4 7.1 0.0 8.0 9 0 0 9 9 7 0 PPR repeat TPR_21 PF09976.9 EAQ83136.1 - 5.1e-07 29.6 13.8 0.024 14.3 0.0 6.3 5 3 1 6 6 6 2 Tetratricopeptide repeat-like domain DUF2225 PF09986.9 EAQ83136.1 - 6.1e-07 29.4 5.0 0.027 14.2 0.0 3.7 2 1 1 3 3 3 2 Uncharacterized protein conserved in bacteria (DUF2225) SPO22 PF08631.10 EAQ83136.1 - 1.9e-06 27.6 2.9 0.0013 18.3 0.0 3.9 5 0 0 5 5 5 2 Meiosis protein SPO22/ZIP4 like DUF2989 PF11207.8 EAQ83136.1 - 3e-06 27.2 0.0 0.27 11.0 0.0 4.0 1 1 3 5 5 5 2 Protein of unknown function (DUF2989) TPR_6 PF13174.6 EAQ83136.1 - 9e-06 26.0 31.6 4 8.3 0.2 9.1 9 0 0 9 9 8 2 Tetratricopeptide repeat SNAP PF14938.6 EAQ83136.1 - 2.4e-05 23.9 7.5 0.21 11.0 0.9 4.5 3 1 1 4 4 4 2 Soluble NSF attachment protein, SNAP RPN6_N PF18055.1 EAQ83136.1 - 2.9e-05 24.4 6.3 0.42 11.0 0.1 5.1 2 2 5 7 7 7 2 26S proteasome regulatory subunit RPN6 N-terminal domain TPR_11 PF13414.6 EAQ83136.1 - 8.5e-05 22.2 45.6 0.19 11.4 1.5 8.6 8 0 0 8 8 8 3 TPR repeat RPN7 PF10602.9 EAQ83136.1 - 0.0011 18.7 4.0 6.1 6.5 0.2 4.8 4 1 2 6 6 6 1 26S proteasome subunit RPN7 DUF3726 PF12525.8 EAQ83136.1 - 0.024 14.7 1.0 1.1 9.4 0.0 3.7 4 0 0 4 4 3 0 Protein of unknown function (DUF3726) 14-3-3 PF00244.20 EAQ83136.1 - 0.035 13.6 3.2 6.6 6.2 0.1 3.8 4 0 0 4 4 4 0 14-3-3 protein SRP68 PF16969.5 EAQ83136.1 - 0.052 12.5 5.6 4.3 6.2 0.1 4.2 2 1 2 5 5 5 0 RNA-binding signal recognition particle 68 Coatomer_E PF04733.14 EAQ83136.1 - 1.1 8.6 4.3 36 3.6 0.1 4.2 4 1 1 5 5 5 0 Coatomer epsilon subunit 4PPT_N PF17837.1 EAQ83139.1 - 0.15 12.2 6.3 1.8 8.7 1.9 3.6 3 0 0 3 3 3 0 4'-phosphopantetheinyl transferase N-terminal domain BTB_2 PF02214.22 EAQ83140.1 - 4e-09 36.7 0.0 8.6e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 EAQ83140.1 - 0.00017 21.8 0.0 0.00031 21.0 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Glyco_hydro_43 PF04616.14 EAQ83141.1 - 1.3e-55 188.8 1.8 1.5e-55 188.5 1.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Pkinase PF00069.25 EAQ83142.1 - 4.6e-22 78.6 0.0 7.5e-22 77.9 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ83142.1 - 0.0066 15.8 0.0 0.0099 15.2 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase DUF4419 PF14388.6 EAQ83143.1 - 2.8e-95 319.2 0.0 3.6e-95 318.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) Glyco_hydro_71 PF03659.14 EAQ83144.1 - 1.3e-119 399.4 5.0 2e-119 398.8 5.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 PP2C PF00481.21 EAQ83145.1 - 5.4e-07 29.5 0.0 7.5e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C FAD_binding_3 PF01494.19 EAQ83146.1 - 7e-10 38.7 0.1 0.00031 20.1 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain FAD_binding_2 PF00890.24 EAQ83146.1 - 1.2e-08 34.4 0.0 2.1e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EAQ83146.1 - 4.1e-08 33.3 0.1 1.8e-07 31.2 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EAQ83146.1 - 3.8e-06 26.7 0.0 7.3e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EAQ83146.1 - 8.2e-06 25.3 0.0 1.4e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EAQ83146.1 - 8.7e-06 26.2 0.0 2e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EAQ83146.1 - 1.3e-05 24.8 0.0 2.2e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EAQ83146.1 - 1.4e-05 24.0 0.0 1.9e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.6 EAQ83146.1 - 0.00072 18.9 0.1 0.0011 18.2 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EAQ83146.1 - 0.0011 18.1 0.0 0.0015 17.7 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 EAQ83146.1 - 0.0014 17.9 0.0 0.0025 17.2 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 EAQ83146.1 - 0.0046 16.2 0.0 0.0088 15.3 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 EAQ83146.1 - 0.012 14.7 0.0 0.022 13.8 0.0 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein Amino_oxidase PF01593.24 EAQ83146.1 - 0.066 12.5 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase NDC10_II PF16787.5 EAQ83148.1 - 3.4e-102 341.7 0.0 5.1e-102 341.2 0.0 1.3 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 GCR1_C PF12550.8 EAQ83148.1 - 6.9e-19 68.0 0.2 1.6e-18 66.8 0.2 1.6 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes SWIB PF02201.18 EAQ83149.1 - 4.6e-31 106.5 1.1 2.1e-30 104.4 0.2 2.2 2 0 0 2 2 2 1 SWIB/MDM2 domain DEK_C PF08766.11 EAQ83149.1 - 5.2e-14 51.9 2.1 1.4e-13 50.6 2.1 1.7 1 0 0 1 1 1 1 DEK C terminal domain SRP-alpha_N PF04086.13 EAQ83149.1 - 0.071 13.0 11.0 0.089 12.7 11.0 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal PPP4R2 PF09184.11 EAQ83149.1 - 0.37 10.3 5.0 0.52 9.8 5.0 1.2 1 0 0 1 1 1 0 PPP4R2 FXMRP1_C_core PF12235.8 EAQ83149.1 - 1.8 9.2 7.5 3.3 8.4 7.5 1.5 1 0 0 1 1 1 0 Fragile X-related 1 protein core C terminal Pkinase PF00069.25 EAQ83150.1 - 4.8e-24 85.1 0.0 9.5e-24 84.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ83150.1 - 6.7e-11 42.0 0.0 1.1e-10 41.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Glyco_hydro_10 PF00331.20 EAQ83151.1 - 1.8e-85 286.9 2.8 1.7e-84 283.7 2.8 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 10 Glyco_hydro_42 PF02449.15 EAQ83151.1 - 0.028 13.7 0.0 0.044 13.1 0.0 1.3 1 0 0 1 1 1 0 Beta-galactosidase zf-C3HC4_3 PF13920.6 EAQ83152.1 - 4.1e-07 29.7 9.2 4.1e-07 29.7 9.2 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EAQ83152.1 - 0.0068 16.2 11.7 0.0068 16.2 11.7 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EAQ83152.1 - 0.012 15.9 11.7 0.012 15.9 11.7 3.1 4 0 0 4 4 4 0 Ring finger domain Med28 PF11594.8 EAQ83152.1 - 0.18 11.9 0.0 0.41 10.7 0.0 1.5 1 0 0 1 1 1 0 Mediator complex subunit 28 Ribonuc_2-5A PF06479.12 EAQ83153.1 - 2e-44 150.8 0.0 3.6e-44 150.0 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase PF00069.25 EAQ83153.1 - 9.1e-37 126.8 0.0 1.3e-26 93.5 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ83153.1 - 8.7e-17 61.3 0.0 3.3e-14 52.8 0.0 2.4 2 1 0 2 2 2 2 Protein tyrosine kinase PQQ PF01011.21 EAQ83153.1 - 1.5e-08 34.2 0.1 6.5e-05 22.7 0.0 3.0 2 0 0 2 2 2 2 PQQ enzyme repeat Kdo PF06293.14 EAQ83153.1 - 0.00014 21.3 0.0 0.00025 20.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PQQ_2 PF13360.6 EAQ83153.1 - 0.00018 21.1 0.2 0.001 18.7 0.2 1.9 1 1 0 1 1 1 1 PQQ-like domain Pkinase_fungal PF17667.1 EAQ83153.1 - 0.0033 16.3 0.0 0.0075 15.1 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EAQ83153.1 - 0.0051 16.8 0.1 0.0051 16.8 0.1 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Acyl-CoA_dh_1 PF00441.24 EAQ83154.1 - 4.5e-34 117.8 1.1 6.5e-34 117.3 1.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EAQ83154.1 - 4.6e-22 78.0 0.0 7.6e-22 77.3 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 EAQ83154.1 - 9.4e-11 42.4 0.1 3.9e-10 40.4 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 EAQ83154.1 - 0.00029 21.1 0.3 0.0005 20.4 0.3 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Methyltransf_25 PF13649.6 EAQ83155.1 - 3e-15 56.7 0.0 6.8e-15 55.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EAQ83155.1 - 4.3e-14 52.9 0.0 8.3e-14 52.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EAQ83155.1 - 1.3e-09 37.8 0.0 2.3e-09 36.9 0.0 1.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 EAQ83155.1 - 6.5e-09 35.8 0.0 9.6e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAQ83155.1 - 1.5e-07 31.3 0.0 1.9e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EAQ83155.1 - 3.7e-06 27.6 0.0 6.9e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.16 EAQ83155.1 - 0.0043 15.7 0.0 0.0054 15.4 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase MTS PF05175.14 EAQ83155.1 - 0.021 14.4 0.0 0.041 13.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain RVT_1 PF00078.27 EAQ83156.1 - 1.2e-37 129.6 0.0 5.8e-37 127.4 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 EAQ83156.1 - 3.9e-26 91.2 0.0 1.3e-25 89.5 0.0 2.0 2 0 0 2 2 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 EAQ83156.1 - 0.00011 21.8 0.2 0.00023 20.8 0.2 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-CCHC PF00098.23 EAQ83156.1 - 0.0026 17.8 1.7 0.0026 17.8 1.7 2.5 2 0 0 2 2 1 1 Zinc knuckle SlyX PF04102.12 EAQ83156.1 - 0.0055 17.3 5.6 0.074 13.7 5.6 2.9 1 1 0 1 1 1 1 SlyX USP8_interact PF08941.10 EAQ83156.1 - 0.062 13.1 0.1 0.19 11.5 0.1 1.9 1 0 0 1 1 1 0 USP8 interacting CorA PF01544.18 EAQ83156.1 - 0.08 12.2 1.5 0.16 11.3 1.5 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein HMMR_N PF15905.5 EAQ83156.1 - 0.081 12.4 0.4 0.14 11.6 0.4 1.3 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal CENP-F_leu_zip PF10473.9 EAQ83156.1 - 0.11 12.5 1.3 0.32 11.0 1.3 1.8 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PKcGMP_CC PF16808.5 EAQ83156.1 - 0.11 12.3 0.5 0.38 10.6 0.5 1.9 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase MLTR_LBD PF17765.1 EAQ83156.1 - 0.15 12.2 2.5 0.72 10.0 0.0 3.2 3 0 0 3 3 3 0 MmyB-like transcription regulator ligand binding domain DUF3584 PF12128.8 EAQ83156.1 - 0.5 7.8 6.0 0.77 7.2 6.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Exonuc_VII_L PF02601.15 EAQ83156.1 - 0.66 9.5 4.6 1.5 8.3 4.6 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit zf-RVT PF13966.6 EAQ83156.1 - 0.7 10.6 0.0 0.7 10.6 0.0 2.8 3 0 0 3 3 2 0 zinc-binding in reverse transcriptase YlqD PF11068.8 EAQ83156.1 - 0.83 10.0 3.6 2.7 8.4 3.6 1.8 1 0 0 1 1 1 0 YlqD protein Helitron_like_N PF14214.6 EAQ83159.1 - 8.3e-39 133.8 2.5 8.3e-39 133.8 2.5 2.3 3 0 0 3 3 3 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.14 EAQ83159.1 - 5.3e-18 65.3 0.0 4.9e-14 52.3 0.0 2.3 2 0 0 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 EAQ83159.1 - 1.2e-06 28.4 0.0 2.7e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAQ83159.1 - 0.0034 17.7 0.0 0.0077 16.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 EAQ83159.1 - 0.096 12.5 0.0 0.24 11.2 0.0 1.7 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Torsin PF06309.11 EAQ83159.1 - 0.11 12.6 0.0 1 9.5 0.0 2.4 2 0 0 2 2 2 0 Torsin CO_deh_flav_C PF03450.17 EAQ83160.1 - 0.13 12.4 0.1 0.28 11.4 0.1 1.5 1 0 0 1 1 1 0 CO dehydrogenase flavoprotein C-terminal domain Clr5 PF14420.6 EAQ83162.1 - 3e-14 52.9 0.3 6.9e-14 51.8 0.3 1.6 1 0 0 1 1 1 1 Clr5 domain DUF3632 PF12311.8 EAQ83163.1 - 3.5e-37 128.5 1.4 3.5e-37 128.5 1.4 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3632) Ribonuclease PF00545.20 EAQ83164.1 - 1.6e-12 48.0 0.0 2.9e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 ribonuclease Serglycin PF04360.12 EAQ83164.1 - 0.02 14.8 2.2 0.032 14.2 2.2 1.3 1 0 0 1 1 1 0 Serglycin Peptidase_M64 PF09471.10 EAQ83164.1 - 0.17 11.4 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 IgA Peptidase M64 SNF2_N PF00176.23 EAQ83167.1 - 2e-07 30.1 0.0 0.0018 17.0 0.0 2.2 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 EAQ83167.1 - 9.3e-06 26.0 0.0 2.5e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Mito_fiss_reg PF05308.11 EAQ83167.1 - 2.4 8.2 5.2 5.1 7.1 5.2 1.5 1 0 0 1 1 1 0 Mitochondrial fission regulator SET PF00856.28 EAQ83168.1 - 1.9e-14 54.4 0.0 2.7e-14 53.9 0.0 1.2 1 0 0 1 1 1 1 SET domain Dynamin_N PF00350.23 EAQ83169.1 - 3.5e-30 105.2 0.0 8.7e-30 104.0 0.0 1.7 1 1 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 EAQ83169.1 - 1.4e-09 37.6 0.0 0.0089 15.3 0.0 3.6 2 1 1 3 3 3 3 Dynamin central region MMR_HSR1 PF01926.23 EAQ83169.1 - 1.2e-05 25.4 0.1 0.00012 22.2 0.1 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_21 PF13304.6 EAQ83169.1 - 0.026 14.4 0.1 0.081 12.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system ZapB PF06005.12 EAQ83169.1 - 0.041 14.3 2.2 0.14 12.6 2.2 1.9 1 0 0 1 1 1 0 Cell division protein ZapB FeoB_N PF02421.18 EAQ83169.1 - 0.083 12.4 0.0 6.2 6.3 0.0 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B GED PF02212.18 EAQ83169.1 - 0.13 12.4 0.7 0.23 11.6 0.2 1.6 2 0 0 2 2 2 0 Dynamin GTPase effector domain AAA_15 PF13175.6 EAQ83169.1 - 0.17 11.6 0.0 0.3 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain RVT_1 PF00078.27 EAQ83170.1 - 8.4e-38 130.1 0.0 4.4e-37 127.8 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 EAQ83170.1 - 2.8e-26 91.7 0.0 1.1e-25 89.8 0.0 2.1 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 EAQ83170.1 - 0.00018 21.1 0.2 0.00039 20.0 0.2 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-CCHC PF00098.23 EAQ83170.1 - 0.0023 18.0 1.7 0.0023 18.0 1.7 2.6 2 0 0 2 2 1 1 Zinc knuckle SlyX PF04102.12 EAQ83170.1 - 0.0049 17.4 5.6 0.066 13.8 5.6 2.8 1 1 0 1 1 1 1 SlyX USP8_interact PF08941.10 EAQ83170.1 - 0.054 13.3 0.1 0.17 11.7 0.1 1.9 1 0 0 1 1 1 0 USP8 interacting CorA PF01544.18 EAQ83170.1 - 0.058 12.7 1.5 0.14 11.5 1.5 1.5 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein HMMR_N PF15905.5 EAQ83170.1 - 0.075 12.5 0.4 0.13 11.7 0.4 1.2 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal CENP-F_leu_zip PF10473.9 EAQ83170.1 - 0.08 13.0 0.9 0.21 11.6 0.9 1.7 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PKcGMP_CC PF16808.5 EAQ83170.1 - 0.14 12.0 0.6 0.35 10.8 0.6 1.7 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF3584 PF12128.8 EAQ83170.1 - 0.26 8.8 4.6 0.41 8.1 4.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) UPF0242 PF06785.11 EAQ83170.1 - 0.27 11.3 1.3 0.58 10.2 1.3 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus YlqD PF11068.8 EAQ83170.1 - 0.9 9.9 3.6 2.4 8.6 3.6 1.6 1 0 0 1 1 1 0 YlqD protein Exonuc_VII_L PF02601.15 EAQ83170.1 - 2.8 7.4 7.3 1.4 8.4 4.5 1.8 2 0 0 2 2 2 0 Exonuclease VII, large subunit KELK PF15796.5 EAQ83170.1 - 7.2 7.1 7.9 14 6.2 3.3 2.8 2 0 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase RVT_1 PF00078.27 EAQ83172.1 - 9.8e-35 120.1 0.0 1.5e-34 119.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RecC_C PF17946.1 EAQ83172.1 - 0.13 12.1 1.9 1.4 8.7 0.9 2.3 2 0 0 2 2 2 0 RecC C-terminal domain Helicase_C PF00271.31 EAQ83173.1 - 3.9e-17 62.6 0.0 9.1e-16 58.2 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 EAQ83173.1 - 2.2e-14 53.6 0.0 1.1e-12 48.1 0.0 2.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 EAQ83173.1 - 0.0047 17.6 0.1 0.013 16.2 0.1 1.7 1 0 0 1 1 1 1 RecQ zinc-binding TrbI_Ftype PF09677.10 EAQ83173.1 - 0.055 13.8 0.0 0.15 12.4 0.0 1.7 1 0 0 1 1 1 0 Type-F conjugative transfer system protein (TrbI_Ftype) HemN_C PF06969.16 EAQ83173.1 - 0.072 13.2 0.0 0.31 11.1 0.0 2.1 1 0 0 1 1 1 0 HemN C-terminal domain TrmB PF01978.19 EAQ83173.1 - 0.077 12.9 0.0 0.23 11.3 0.0 1.8 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB SNF2_N PF00176.23 EAQ83173.1 - 0.17 10.6 0.0 0.26 10.0 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain DDE_1 PF03184.19 EAQ83174.1 - 9.4e-27 93.8 0.0 1.4e-26 93.2 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.16 EAQ83174.1 - 0.0025 17.5 0.0 0.0058 16.3 0.0 1.7 1 0 0 1 1 1 1 helix-turn-helix, Psq domain DDE_3 PF13358.6 EAQ83174.1 - 0.016 14.9 0.0 0.062 13.1 0.0 1.9 2 0 0 2 2 2 0 DDE superfamily endonuclease TIM PF00121.18 EAQ83174.1 - 0.059 12.7 0.0 0.092 12.1 0.0 1.2 1 0 0 1 1 1 0 Triosephosphate isomerase HTH_Tnp_Tc5 PF03221.16 EAQ83174.1 - 0.079 13.0 0.0 0.2 11.7 0.0 1.7 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain zf-MYND PF01753.18 EAQ83175.1 - 8.5e-10 38.6 10.7 1.3e-09 38.0 10.7 1.3 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.6 EAQ83175.1 - 1.1 9.4 4.2 2.3 8.4 4.2 1.5 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 Glyco_hydro_61 PF03443.14 EAQ83177.1 - 3.2e-31 108.9 0.0 3.6e-31 108.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 SET PF00856.28 EAQ83178.1 - 2.2e-08 34.7 0.0 6.5e-08 33.1 0.0 1.9 1 1 0 2 2 2 1 SET domain CSTF_C PF14304.6 EAQ83178.1 - 0.041 13.5 0.6 0.087 12.4 0.6 1.5 1 0 0 1 1 1 0 Transcription termination and cleavage factor C-terminal Goodbye PF17109.5 EAQ83179.1 - 0.19 12.1 0.0 0.38 11.2 0.0 1.5 1 0 0 1 1 1 0 fungal STAND N-terminal Goodbye domain Orthopox_C10L PF07020.11 EAQ83179.1 - 0.28 12.0 2.3 1.5 9.6 2.0 2.2 1 1 0 1 1 1 0 Orthopoxvirus C10L protein adh_short_C2 PF13561.6 EAQ83180.1 - 2.8e-20 72.9 2.7 1.4e-12 47.7 0.1 2.2 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EAQ83180.1 - 6.3e-14 51.9 0.3 2e-08 34.0 0.2 2.2 1 1 1 2 2 2 2 short chain dehydrogenase KR PF08659.10 EAQ83180.1 - 0.00013 21.9 0.3 0.00024 21.0 0.3 1.3 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 EAQ83180.1 - 0.049 13.5 0.1 0.085 12.7 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 EAQ83180.1 - 0.096 12.0 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 EAQ83180.1 - 0.097 13.3 0.1 0.19 12.3 0.1 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ketoacyl-synt PF00109.26 EAQ83181.1 - 4.4e-66 223.0 2.1 1.8e-65 221.1 0.0 2.9 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 EAQ83181.1 - 5.4e-61 205.6 0.0 1.5e-60 204.2 0.0 1.8 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 EAQ83181.1 - 9.6e-43 146.5 2.7 3.6e-31 108.5 0.0 2.8 2 1 1 3 3 3 2 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 EAQ83181.1 - 2.6e-20 72.6 0.0 1.4e-13 50.9 0.0 2.6 1 1 1 2 2 2 2 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.25 EAQ83181.1 - 3e-13 49.7 0.0 8.4e-13 48.2 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase ADH_zinc_N PF00107.26 EAQ83181.1 - 4.7e-12 46.0 0.0 2.6e-11 43.6 0.0 2.3 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.12 EAQ83181.1 - 5.8e-12 46.2 0.0 2e-11 44.5 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Acyl_transf_1 PF00698.21 EAQ83181.1 - 9.6e-12 45.0 2.1 4.2e-10 39.6 0.9 2.6 2 0 0 2 2 2 1 Acyl transferase domain ADH_zinc_N_2 PF13602.6 EAQ83181.1 - 2.8e-11 44.6 0.0 2.1e-10 41.8 0.0 2.5 3 0 0 3 3 1 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.6 EAQ83181.1 - 3.4e-09 36.7 0.0 8.5e-09 35.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAQ83181.1 - 5.3e-08 33.5 0.1 6.9e-07 29.9 0.0 2.9 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EAQ83181.1 - 5.2e-07 30.2 0.1 0.00018 22.1 0.0 3.3 3 0 0 3 3 3 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 EAQ83181.1 - 7.4e-07 29.6 0.0 1.9e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension PP-binding PF00550.25 EAQ83181.1 - 1.4e-05 25.4 0.4 4.8e-05 23.6 0.4 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.23 EAQ83181.1 - 7.9e-05 22.1 0.1 0.00019 20.9 0.1 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_31 PF13847.6 EAQ83181.1 - 0.00011 22.0 0.0 0.00024 21.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_28 PF02636.17 EAQ83181.1 - 0.0064 16.2 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Lipase_GDSL_2 PF13472.6 EAQ83181.1 - 0.0078 16.6 0.0 8 6.8 0.0 3.5 2 1 1 3 3 2 1 GDSL-like Lipase/Acylhydrolase family Polysacc_synt_2 PF02719.15 EAQ83181.1 - 0.016 14.3 0.0 0.026 13.6 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Methyltransf_24 PF13578.6 EAQ83181.1 - 0.033 15.2 0.0 0.43 11.6 0.0 3.1 2 0 0 2 2 1 0 Methyltransferase domain GDP_Man_Dehyd PF16363.5 EAQ83181.1 - 0.21 10.9 0.0 0.35 10.2 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase ketoacyl-synt PF00109.26 EAQ83182.1 - 1.1e-47 162.8 0.1 4.1e-47 160.9 0.0 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain HTH_51 PF18558.1 EAQ83182.1 - 1.2e-31 108.5 0.0 3.8e-31 106.8 0.0 2.0 1 0 0 1 1 1 1 Helix-turn-helix domain NAD_binding_4 PF07993.12 EAQ83182.1 - 1.3e-23 83.5 0.0 1.9e-23 82.9 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Acyl_transf_1 PF00698.21 EAQ83182.1 - 3.3e-22 79.4 0.0 8e-22 78.1 0.0 1.6 1 0 0 1 1 1 1 Acyl transferase domain Methyltransf_12 PF08242.12 EAQ83182.1 - 2.5e-14 53.8 0.0 6.9e-14 52.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain SAT PF16073.5 EAQ83182.1 - 7.6e-13 48.7 0.4 1.3e-09 38.1 0.2 3.0 2 1 0 2 2 2 2 Starter unit:ACP transacylase in aflatoxin biosynthesis PS-DH PF14765.6 EAQ83182.1 - 8.9e-12 44.8 0.0 2e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 EAQ83182.1 - 6e-10 39.2 0.1 1.5e-09 37.9 0.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_23 PF13489.6 EAQ83182.1 - 1.6e-09 37.9 0.0 9.2e-09 35.4 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAQ83182.1 - 7.6e-09 36.2 0.0 2.6e-08 34.5 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 EAQ83182.1 - 3.9e-08 33.5 5.0 5.4e-08 33.1 2.5 2.5 2 0 0 2 2 2 1 Phosphopantetheine attachment site Methyltransf_11 PF08241.12 EAQ83182.1 - 1.4e-07 32.0 0.0 6.1e-07 30.0 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAQ83182.1 - 1.2e-06 28.4 0.0 2.7e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.21 EAQ83182.1 - 0.00012 21.6 0.0 0.00023 20.7 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KAsynt_C_assoc PF16197.5 EAQ83182.1 - 0.00016 22.1 0.0 0.00036 21.0 0.0 1.6 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension KR PF08659.10 EAQ83182.1 - 0.026 14.4 0.0 0.058 13.3 0.0 1.6 1 0 0 1 1 1 0 KR domain NodS PF05401.11 EAQ83182.1 - 0.035 13.7 0.0 0.15 11.7 0.0 1.9 2 0 0 2 2 2 0 Nodulation protein S (NodS) Thiolase_N PF00108.23 EAQ83182.1 - 0.054 12.8 0.2 0.21 10.9 0.1 1.9 2 0 0 2 2 2 0 Thiolase, N-terminal domain Polysacc_synt_2 PF02719.15 EAQ83182.1 - 0.065 12.4 0.0 0.4 9.8 0.0 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein MFS_1 PF07690.16 EAQ83183.1 - 4.8e-37 127.7 43.2 4.8e-37 127.7 43.2 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Trp_halogenase PF04820.14 EAQ83184.1 - 8.8e-26 90.8 0.1 3.7e-13 49.2 0.1 2.5 2 1 0 2 2 2 2 Tryptophan halogenase FAD_binding_3 PF01494.19 EAQ83184.1 - 5e-13 49.0 0.1 3.9e-12 46.1 0.1 2.3 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EAQ83184.1 - 1e-05 25.6 0.1 3.9e-05 23.8 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EAQ83184.1 - 1.4e-05 24.5 0.0 2.5e-05 23.7 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EAQ83184.1 - 1.6e-05 24.4 1.4 0.00021 20.8 1.3 2.6 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EAQ83184.1 - 0.00018 20.8 0.1 0.0004 19.6 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 EAQ83184.1 - 0.0007 18.4 0.0 0.0011 17.7 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.22 EAQ83184.1 - 0.0015 17.7 0.1 0.0024 17.0 0.1 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A DAO PF01266.24 EAQ83184.1 - 0.0018 17.9 0.5 0.014 15.0 0.2 2.3 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EAQ83184.1 - 0.017 15.7 0.1 0.058 14.0 0.0 2.0 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EAQ83184.1 - 0.035 13.4 0.0 0.12 11.6 0.0 1.8 2 0 0 2 2 2 0 Thi4 family Pyr_redox_3 PF13738.6 EAQ83184.1 - 0.065 12.5 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 EAQ83184.1 - 0.1 13.0 0.0 0.4 11.2 0.0 2.0 2 0 0 2 2 2 0 Putative NAD(P)-binding AlaDh_PNT_C PF01262.21 EAQ83184.1 - 0.12 11.6 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Zn_clus PF00172.18 EAQ83185.1 - 1.3e-08 34.8 8.6 2.8e-08 33.8 8.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EAQ83185.1 - 4.5e-08 32.4 0.1 1.1e-07 31.2 0.1 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Cu_amine_oxid PF01179.20 EAQ83187.1 - 8e-159 528.9 0.0 9.5e-159 528.7 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.16 EAQ83187.1 - 2.7e-08 33.9 0.0 5.3e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain PsiA PF06952.11 EAQ83188.1 - 0.17 11.1 1.0 0.27 10.5 1.0 1.3 1 0 0 1 1 1 0 PsiA protein Myb_DNA-binding PF00249.31 EAQ83189.1 - 2.2e-19 69.4 9.3 1.2e-09 38.2 0.1 4.6 5 0 0 5 5 5 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAQ83189.1 - 2.1e-16 59.9 11.7 5e-11 42.7 0.1 4.3 3 1 1 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 EAQ83189.1 - 8.9 6.8 7.3 2.1 8.8 1.1 3.1 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain AAA_16 PF13191.6 EAQ83191.1 - 1.4e-08 35.3 0.0 3.7e-08 33.9 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain PRIMA1 PF16101.5 EAQ83191.1 - 0.023 14.7 6.3 0.043 13.9 6.3 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 AAA_25 PF13481.6 EAQ83191.1 - 0.03 13.9 0.1 0.091 12.3 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EAQ83191.1 - 0.057 12.9 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_22 PF13401.6 EAQ83191.1 - 0.079 13.2 0.2 0.27 11.5 0.2 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAQ83191.1 - 0.11 13.0 0.0 0.26 11.7 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 EAQ83191.1 - 0.11 11.6 0.0 0.21 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) CAP_N PF01213.19 EAQ83191.1 - 0.35 10.3 9.6 0.84 9.1 9.6 1.6 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.11 EAQ83191.1 - 0.96 9.5 6.1 1.7 8.6 6.1 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator Fungal_trans_2 PF11951.8 EAQ83192.1 - 7.3e-31 107.3 2.2 5.6e-19 68.2 0.7 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 EAQ83192.1 - 2.3e-08 34.0 11.5 3.8e-08 33.3 11.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PSDC PF12588.8 EAQ83194.1 - 3.6e-58 195.5 0.0 5.7e-58 194.9 0.0 1.3 1 0 0 1 1 1 1 Phophatidylserine decarboxylase PS_Dcarbxylase PF02666.15 EAQ83194.1 - 1e-37 129.7 0.0 2.2e-37 128.6 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase zf-C2H2_3 PF13878.6 EAQ83194.1 - 3.8e-07 29.8 0.0 8.4e-07 28.7 0.0 1.6 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Biotin_lipoyl_2 PF13533.6 EAQ83194.1 - 0.00036 20.3 0.0 0.15 12.0 0.1 2.4 2 0 0 2 2 2 2 Biotin-lipoyl like Vma12 PF11712.8 EAQ83195.1 - 1e-43 148.7 0.0 1.6e-43 148.1 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase FUSC PF04632.12 EAQ83195.1 - 0.013 14.1 0.0 0.016 13.8 0.0 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF1358 PF07096.11 EAQ83195.1 - 0.081 12.9 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1358) polyprenyl_synt PF00348.17 EAQ83196.1 - 2.9e-74 249.4 0.0 9.4e-74 247.7 0.0 1.7 1 1 0 1 1 1 1 Polyprenyl synthetase HEPPP_synt_1 PF07307.11 EAQ83196.1 - 0.0093 15.6 0.0 0.014 15.0 0.0 1.2 1 0 0 1 1 1 1 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 SQS_PSY PF00494.19 EAQ83196.1 - 0.06 12.8 0.5 0.16 11.4 0.1 1.9 2 0 0 2 2 2 0 Squalene/phytoene synthase ADH_N_2 PF16884.5 EAQ83197.1 - 2.9e-26 91.5 0.0 9.5e-26 89.8 0.0 1.8 2 0 0 2 2 2 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 EAQ83197.1 - 6.1e-21 74.8 0.0 1e-20 74.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EAQ83197.1 - 1.8e-06 29.0 0.0 3.7e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Amidohydro_1 PF01979.20 EAQ83198.1 - 2.8e-27 95.9 0.0 1.6e-16 60.5 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 EAQ83198.1 - 1.1e-14 54.8 0.7 3.2e-09 36.8 0.1 2.2 2 0 0 2 2 2 2 Amidohydrolase family PIP5K PF01504.18 EAQ83199.1 - 4.3e-103 344.3 0.2 7.1e-103 343.6 0.2 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase COX6B PF02297.17 EAQ83200.1 - 6e-23 80.9 2.3 7.3e-23 80.6 2.3 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Pet191_N PF10203.9 EAQ83200.1 - 0.097 13.0 0.2 0.2 12.0 0.2 1.5 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 SYS1 PF09801.9 EAQ83201.1 - 1e-51 174.9 6.2 1.2e-51 174.7 6.2 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network CHD5 PF04420.14 EAQ83201.1 - 0.24 11.2 1.2 0.41 10.5 1.2 1.3 1 0 0 1 1 1 0 CHD5-like protein GPDPase_memb PF10110.9 EAQ83201.1 - 1.2 7.8 5.6 1.5 7.5 5.6 1.1 1 0 0 1 1 1 0 Membrane domain of glycerophosphoryl diester phosphodiesterase Acyl-CoA_dh_N PF02771.16 EAQ83202.1 - 4.2e-25 88.6 0.1 7.1e-25 87.9 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 EAQ83202.1 - 5.8e-17 62.3 0.1 1.1e-16 61.4 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EAQ83202.1 - 0.00013 22.1 0.0 0.039 14.1 0.0 2.5 1 1 1 2 2 2 2 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EAQ83202.1 - 0.0043 17.3 0.2 0.0079 16.5 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain UQ_con PF00179.26 EAQ83203.1 - 2.4e-52 176.3 0.0 2.7e-52 176.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EAQ83203.1 - 0.0012 18.5 0.0 0.0015 18.3 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 EAQ83203.1 - 0.011 16.1 0.0 0.014 15.6 0.0 1.3 1 0 0 1 1 1 0 RWD domain UEV PF05743.13 EAQ83203.1 - 0.043 13.7 0.0 0.069 13.0 0.0 1.3 1 0 0 1 1 1 0 UEV domain NAD_binding_6 PF08030.12 EAQ83205.1 - 1.4e-31 109.8 0.0 2.9e-31 108.7 0.0 1.6 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EAQ83205.1 - 3.9e-20 72.0 0.9 7.5e-20 71.0 0.0 2.0 2 0 0 2 2 2 1 FAD-binding domain Ferric_reduct PF01794.19 EAQ83205.1 - 2.1e-18 66.6 11.6 2.1e-18 66.6 11.6 2.4 1 1 1 2 2 2 2 Ferric reductase like transmembrane component XPG_I PF00867.18 EAQ83206.1 - 6.4e-31 106.6 0.9 1.6e-30 105.3 0.0 2.0 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.17 EAQ83206.1 - 3.5e-20 72.4 0.0 1.1e-19 70.8 0.0 1.8 1 0 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc PF01367.20 EAQ83206.1 - 2.7e-05 24.7 0.2 0.0002 21.9 0.0 2.4 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold HHH_5 PF14520.6 EAQ83206.1 - 0.052 14.2 0.0 0.12 13.1 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix domain PVL_ORF50 PF07768.11 EAQ83206.1 - 2.9 8.2 9.9 14 6.0 3.2 2.5 2 0 0 2 2 2 0 PVL ORF-50-like family U1snRNP70_N PF12220.8 EAQ83206.1 - 8 7.2 11.2 0.29 11.8 2.7 2.4 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Acyl-CoA_dh_1 PF00441.24 EAQ83207.1 - 2.1e-42 144.9 0.1 3e-42 144.4 0.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.28 EAQ83207.1 - 2e-18 66.3 0.2 4.2e-18 65.2 0.2 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.16 EAQ83207.1 - 6.2e-17 62.3 0.0 1.3e-16 61.2 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EAQ83207.1 - 5.4e-15 55.4 0.1 1.1e-14 54.4 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EAQ83207.1 - 4.9e-08 33.3 0.0 8.5e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Ribosomal_60s PF00428.19 EAQ83207.1 - 0.12 12.9 6.9 0.25 11.9 6.9 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein Tim17 PF02466.19 EAQ83208.1 - 9.4e-11 42.1 7.6 1.2e-10 41.7 6.3 1.9 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family UCH PF00443.29 EAQ83209.1 - 3.9e-29 101.9 0.0 5.8e-29 101.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.6 EAQ83209.1 - 6.3e-09 35.6 0.0 0.031 14.2 0.0 3.7 3 0 0 3 3 3 3 A repeated domain in UCH-protein UCH_1 PF13423.6 EAQ83209.1 - 1.8e-07 31.0 0.1 0.0047 16.6 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase PUB PF09409.10 EAQ83209.1 - 0.006 16.5 0.0 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 PUB domain IF2_N PF04760.15 EAQ83209.1 - 0.051 13.4 2.7 0.33 10.8 0.0 2.9 3 0 0 3 3 3 0 Translation initiation factor IF-2, N-terminal region MutS_V PF00488.21 EAQ83210.1 - 7.6e-83 277.2 0.3 1.4e-82 276.3 0.3 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EAQ83210.1 - 2e-37 129.3 1.1 6.8e-37 127.5 0.7 2.1 2 0 0 2 2 2 1 MutS domain III MutS_II PF05188.17 EAQ83210.1 - 2.6e-20 73.1 0.5 1e-19 71.2 0.1 2.4 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.18 EAQ83210.1 - 3.4e-19 69.0 0.9 2.4e-18 66.3 0.4 2.6 2 0 0 2 2 2 1 MutS family domain IV MutS_I PF01624.20 EAQ83210.1 - 9.4e-18 64.5 0.0 6.4e-17 61.8 0.0 2.2 2 0 0 2 2 2 1 MutS domain I AAA_27 PF13514.6 EAQ83210.1 - 0.037 13.6 0.0 0.18 11.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain Com_YlbF PF06133.11 EAQ83210.1 - 0.42 11.2 5.4 0.37 11.4 0.5 3.2 3 0 0 3 3 3 0 Control of competence regulator ComK, YlbF/YmcA tRNA_m1G_MT PF01746.21 EAQ83211.1 - 8.9e-24 84.3 3.7 6.5e-17 61.9 0.0 2.7 3 0 0 3 3 3 2 tRNA (Guanine-1)-methyltransferase PAP_PilO PF06864.12 EAQ83211.1 - 0.031 13.1 2.0 0.048 12.5 2.0 1.2 1 0 0 1 1 1 0 Pilin accessory protein (PilO) Presenilin PF01080.17 EAQ83211.1 - 2.4 6.8 6.0 3.5 6.3 6.0 1.2 1 0 0 1 1 1 0 Presenilin AC_N PF16214.5 EAQ83211.1 - 4.2 6.4 7.5 6.7 5.7 7.5 1.2 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region DNA_primase_S PF01896.19 EAQ83212.1 - 1e-61 208.0 0.3 1.5e-61 207.5 0.3 1.2 1 0 0 1 1 1 1 DNA primase small subunit Glyco_hydro_5_C PF18564.1 EAQ83213.1 - 0.0058 17.1 0.0 0.014 15.9 0.0 1.6 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain Pkinase PF00069.25 EAQ83214.1 - 4.2e-39 134.5 0.2 9.2e-33 113.7 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ83214.1 - 3.3e-25 88.9 0.3 1.7e-23 83.3 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EAQ83214.1 - 0.00022 20.6 0.0 0.0052 16.1 0.0 2.1 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 EAQ83214.1 - 0.00086 18.7 0.0 0.0016 17.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EAQ83214.1 - 0.0066 16.4 0.0 0.053 13.4 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EAQ83214.1 - 0.008 15.0 0.0 0.017 13.9 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Menin PF05053.13 EAQ83214.1 - 5.5 5.2 6.4 9.8 4.4 6.4 1.3 1 0 0 1 1 1 0 Menin Glyco_hydro_47 PF01532.20 EAQ83215.1 - 1.2e-181 604.6 0.1 1.6e-181 604.3 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Apidaecin PF00807.17 EAQ83215.1 - 0.8 9.9 10.6 5 7.3 10.6 2.4 1 0 0 1 1 1 0 Apidaecin Fig1 PF12351.8 EAQ83216.1 - 1.8e-56 191.1 5.0 2.6e-56 190.5 5.0 1.2 1 0 0 1 1 1 1 Ca2+ regulator and membrane fusion protein Fig1 DUF898 PF05987.13 EAQ83216.1 - 0.00098 18.3 3.3 0.0012 17.9 3.3 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF898) SUR7 PF06687.12 EAQ83216.1 - 0.0013 18.4 11.3 0.0013 18.4 11.3 1.7 1 1 0 1 1 1 1 SUR7/PalI family B12-binding PF02310.19 EAQ83216.1 - 0.093 12.8 0.0 0.96 9.5 0.0 2.4 3 0 0 3 3 3 0 B12 binding domain DASH_Spc34 PF08657.10 EAQ83217.1 - 3e-17 63.3 5.5 2.1e-13 50.7 0.2 2.3 2 1 1 3 3 3 2 DASH complex subunit Spc34 ERM PF00769.19 EAQ83217.1 - 0.0062 16.4 0.1 0.0074 16.1 0.1 1.1 1 0 0 1 1 1 1 Ezrin/radixin/moesin family DUF4741 PF15897.5 EAQ83217.1 - 0.062 13.1 1.2 0.087 12.6 1.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4741) DUF4140 PF13600.6 EAQ83217.1 - 0.12 12.8 0.4 0.19 12.2 0.4 1.4 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Sporozoite_P67 PF05642.11 EAQ83218.1 - 0.022 12.9 7.8 0.037 12.1 7.8 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen AF-4 PF05110.13 EAQ83218.1 - 0.46 8.5 9.0 0.49 8.4 9.0 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein TFIID_20kDa PF03847.13 EAQ83219.1 - 3.3e-17 62.7 0.0 5.8e-17 62.0 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A NolV PF06635.12 EAQ83219.1 - 0.053 12.9 0.0 0.096 12.1 0.0 1.4 1 0 0 1 1 1 0 Nodulation protein NolV DUF913 PF06025.12 EAQ83219.1 - 0.8 8.6 7.3 1.7 7.5 7.3 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) V_ATPase_I PF01496.19 EAQ83219.1 - 1.4 6.8 8.8 2.7 5.8 8.8 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TFB6 PF17110.5 EAQ83219.1 - 3.4 7.4 5.3 6 6.6 5.3 1.3 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH DUF3810 PF12725.7 EAQ83219.1 - 4.3 6.6 5.7 7.1 5.9 5.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Rpn3_C PF08375.11 EAQ83220.1 - 5e-26 90.9 1.7 1.6e-25 89.3 1.7 1.9 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI PF01399.27 EAQ83220.1 - 5.3e-20 71.9 0.3 2.1e-19 70.0 0.0 2.2 3 0 0 3 3 3 1 PCI domain TPR_2 PF07719.17 EAQ83220.1 - 0.015 15.4 0.1 0.051 13.7 0.1 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat zf-RING_2 PF13639.6 EAQ83221.1 - 0.0019 18.5 5.8 0.0034 17.7 5.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EAQ83221.1 - 0.011 15.6 2.5 0.021 14.7 2.5 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EAQ83221.1 - 0.033 14.0 6.4 0.062 13.2 6.4 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EAQ83221.1 - 0.054 13.5 2.0 0.11 12.6 2.0 1.5 1 0 0 1 1 1 0 RING-type zinc-finger Aminotran_3 PF00202.21 EAQ83221.1 - 0.088 11.4 0.0 0.13 10.9 0.0 1.1 1 0 0 1 1 1 0 Aminotransferase class-III zf-C3HC4_3 PF13920.6 EAQ83221.1 - 0.21 11.5 6.1 0.33 10.8 6.1 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EAQ83221.1 - 1.3 8.9 6.8 2.6 7.9 6.8 1.5 1 0 0 1 1 1 0 RING-like zinc finger Drc1-Sld2 PF11719.8 EAQ83222.1 - 1e-57 196.7 23.2 5.6e-57 194.3 23.2 1.9 1 1 0 1 1 1 1 DNA replication and checkpoint protein DNA_methylase PF00145.17 EAQ83224.1 - 3.3e-27 95.7 0.0 2.1e-26 93.1 0.0 2.1 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase BAH PF01426.18 EAQ83224.1 - 0.00047 20.0 0.0 0.014 15.2 0.0 2.4 2 0 0 2 2 2 1 BAH domain Smoothelin PF12510.8 EAQ83224.1 - 1.5 8.9 3.6 3.5 7.7 2.8 2.0 1 1 1 2 2 2 0 Smoothelin cytoskeleton protein MOZ_SAS PF01853.18 EAQ83225.1 - 1.6e-50 171.2 0.0 3e-50 170.4 0.0 1.3 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 EAQ83225.1 - 3e-08 33.1 0.6 0.0087 15.6 0.5 2.5 2 0 0 2 2 2 2 MYST family zinc finger domain Acetyltransf_7 PF13508.7 EAQ83225.1 - 0.016 15.6 0.0 0.047 14.1 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EAQ83225.1 - 0.071 13.3 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family ATP-synt_C PF00137.21 EAQ83226.1 - 1.5e-05 25.2 7.6 1.5e-05 25.2 7.6 2.1 2 0 0 2 2 2 1 ATP synthase subunit C IncE PF17627.2 EAQ83226.1 - 0.52 10.3 3.7 0.72 9.9 3.7 1.4 1 1 0 1 1 1 0 Inclusion membrane protein E iPGM_N PF06415.13 EAQ83227.1 - 1.3e-78 263.4 0.0 1.9e-78 262.8 0.0 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Metalloenzyme PF01676.18 EAQ83227.1 - 1.5e-68 230.9 0.0 1.7e-68 230.7 0.0 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 EAQ83227.1 - 5e-05 22.9 0.0 0.00015 21.3 0.0 1.9 1 1 0 1 1 1 1 Sulfatase AP_endonuc_2 PF01261.24 EAQ83227.1 - 0.075 12.5 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Med9 PF07544.13 EAQ83228.1 - 1.3e-13 50.8 0.0 2e-13 50.2 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 TFIIA PF03153.13 EAQ83228.1 - 1.6 8.7 5.0 1.9 8.4 5.0 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Mucin PF01456.17 EAQ83228.1 - 2 8.4 13.2 3.2 7.7 13.2 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein TBCC PF07986.12 EAQ83229.1 - 6.8e-29 100.0 0.3 2e-27 95.3 0.1 2.3 2 0 0 2 2 2 1 Tubulin binding cofactor C TBCC_N PF16752.5 EAQ83229.1 - 3.2e-07 30.8 0.1 6e-07 29.9 0.1 1.5 1 0 0 1 1 1 1 Tubulin-specific chaperone C N-terminal domain WES_acyltransf PF03007.16 EAQ83229.1 - 0.0035 17.1 0.0 0.013 15.2 0.0 1.9 1 1 0 2 2 2 1 Wax ester synthase-like Acyl-CoA acyltransferase domain DUF3580 PF12117.8 EAQ83229.1 - 0.02 15.1 1.6 0.02 15.1 1.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3580) Gpi1 PF05024.15 EAQ83230.1 - 1.2e-77 260.2 6.7 2.3e-77 259.3 6.7 1.4 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) 7tm_1 PF00001.21 EAQ83230.1 - 0.0018 17.7 0.5 0.0043 16.4 0.5 1.6 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DNA_pol_A_exo1 PF01612.20 EAQ83231.1 - 2.3e-40 138.1 0.2 3.6e-40 137.5 0.2 1.3 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.12 EAQ83231.1 - 4.7e-26 91.3 1.9 7.7e-26 90.6 0.4 2.2 2 0 0 2 2 2 1 PMC2NT (NUC016) domain HRDC PF00570.23 EAQ83231.1 - 3e-14 52.7 0.0 1.1e-13 50.9 0.0 2.1 2 0 0 2 2 2 1 HRDC domain Rsd_AlgQ PF04353.13 EAQ83231.1 - 0.047 13.6 0.1 0.61 10.0 0.0 2.7 3 0 0 3 3 3 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ Asp PF00026.23 EAQ83232.1 - 2.3e-111 372.2 0.3 2.7e-111 372.0 0.3 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EAQ83232.1 - 2.9e-17 63.5 0.7 2.2e-15 57.4 0.4 2.9 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EAQ83232.1 - 7.7e-06 26.5 0.1 0.51 11.0 0.0 3.4 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 EAQ83232.1 - 0.0014 19.1 0.0 3.5 8.3 0.0 2.9 2 1 0 2 2 2 2 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 EAQ83232.1 - 0.048 13.4 0.0 0.59 9.9 0.0 2.4 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal Lge1 PF11488.8 EAQ83232.1 - 0.19 12.0 0.2 0.32 11.2 0.2 1.3 1 0 0 1 1 1 0 Transcriptional regulatory protein LGE1 Prefoldin PF02996.17 EAQ83233.1 - 4.6e-05 23.3 0.0 8.2e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Prefoldin subunit CRAL_TRIO PF00650.20 EAQ83234.1 - 2.8e-36 124.7 0.0 4.6e-36 123.9 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EAQ83234.1 - 4.6e-07 29.9 0.2 4.6e-07 29.9 0.2 2.1 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 EAQ83234.1 - 0.026 14.7 0.0 0.046 13.9 0.0 1.3 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain DUF1769 PF08588.10 EAQ83234.1 - 0.069 13.4 0.0 0.16 12.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1769) Mis14 PF08641.12 EAQ83235.1 - 5.1e-08 33.3 0.1 8.6e-08 32.6 0.1 1.5 1 1 0 1 1 1 1 Kinetochore protein Mis14 like AAA PF00004.29 EAQ83237.1 - 2.4e-45 154.2 0.1 7.7e-45 152.6 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 EAQ83237.1 - 6e-10 38.9 0.1 4e-09 36.3 0.0 2.3 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 EAQ83237.1 - 1.8e-08 34.5 0.4 6.6e-08 32.6 0.1 2.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EAQ83237.1 - 5.3e-08 33.2 0.0 1.1e-07 32.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 EAQ83237.1 - 1.1e-07 32.4 0.1 3.7e-05 24.2 0.0 3.0 2 1 1 3 3 3 1 AAA ATPase domain DUF815 PF05673.13 EAQ83237.1 - 3.3e-06 26.5 0.0 6.9e-06 25.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 EAQ83237.1 - 3.3e-05 24.2 0.9 0.0088 16.3 0.1 2.7 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 EAQ83237.1 - 0.00025 20.8 0.0 0.00073 19.3 0.0 1.8 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 EAQ83237.1 - 0.00048 20.7 0.0 0.0013 19.3 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_28 PF13521.6 EAQ83237.1 - 0.00064 20.0 0.0 0.0014 18.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 EAQ83237.1 - 0.00072 19.1 0.1 0.0032 17.0 0.1 2.0 1 1 0 1 1 1 1 P-loop containing dynein motor region TIP49 PF06068.13 EAQ83237.1 - 0.0011 18.3 0.0 0.002 17.4 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_lid_3 PF17862.1 EAQ83237.1 - 0.0012 18.6 0.0 0.0031 17.3 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain TsaE PF02367.17 EAQ83237.1 - 0.0013 18.7 0.0 0.019 15.0 0.0 2.2 1 1 1 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 EAQ83237.1 - 0.0017 18.4 0.2 0.0078 16.3 0.0 2.2 3 0 0 3 3 2 1 AAA domain RNA_helicase PF00910.22 EAQ83237.1 - 0.0022 18.3 0.0 0.0046 17.3 0.0 1.5 1 0 0 1 1 1 1 RNA helicase NTPase_1 PF03266.15 EAQ83237.1 - 0.003 17.5 0.0 0.015 15.2 0.0 2.1 2 0 0 2 2 2 1 NTPase AAA_3 PF07726.11 EAQ83237.1 - 0.0056 16.5 0.0 0.018 14.9 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 EAQ83237.1 - 0.0072 15.7 0.2 0.016 14.6 0.1 1.7 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 EAQ83237.1 - 0.008 16.3 0.0 0.019 15.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 EAQ83237.1 - 0.0084 16.0 0.3 0.11 12.3 0.0 2.4 1 1 1 2 2 2 1 NACHT domain IstB_IS21 PF01695.17 EAQ83237.1 - 0.011 15.5 0.1 0.03 14.0 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_30 PF13604.6 EAQ83237.1 - 0.011 15.5 1.4 0.013 15.2 0.1 1.9 2 1 0 2 2 1 0 AAA domain TniB PF05621.11 EAQ83237.1 - 0.013 14.9 0.0 0.5 9.7 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein Viral_Hsp90 PF03225.14 EAQ83237.1 - 0.015 13.8 0.0 0.023 13.3 0.0 1.2 1 0 0 1 1 1 0 Viral heat shock protein Hsp90 homologue AAA_24 PF13479.6 EAQ83237.1 - 0.02 14.6 0.2 0.055 13.2 0.2 1.8 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 EAQ83237.1 - 0.034 14.0 0.9 0.34 10.8 0.0 2.6 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea ATPase PF06745.13 EAQ83237.1 - 0.038 13.3 1.3 0.56 9.5 0.0 2.6 3 0 0 3 3 3 0 KaiC Bac_DnaA PF00308.18 EAQ83237.1 - 0.04 13.8 0.0 0.077 12.8 0.0 1.5 1 0 0 1 1 1 0 Bacterial dnaA protein AAA_11 PF13086.6 EAQ83237.1 - 0.041 13.7 0.1 0.14 12.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 EAQ83237.1 - 0.069 12.9 0.2 1.3 8.7 0.0 2.5 2 1 0 2 2 2 0 Sigma-54 interaction domain AFG1_ATPase PF03969.16 EAQ83237.1 - 0.072 12.0 0.0 0.13 11.1 0.0 1.4 1 0 0 1 1 1 0 AFG1-like ATPase AAA_25 PF13481.6 EAQ83237.1 - 0.076 12.6 1.4 0.21 11.1 0.3 2.2 2 1 1 3 3 3 0 AAA domain Zeta_toxin PF06414.12 EAQ83237.1 - 0.084 12.1 0.0 0.22 10.8 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin SPACA9 PF15120.6 EAQ83237.1 - 0.095 12.5 0.8 14 5.4 0.0 2.2 2 0 0 2 2 2 0 Sperm acrosome-associated protein 9 AAA_19 PF13245.6 EAQ83237.1 - 0.12 12.6 0.1 0.37 11.1 0.1 1.7 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 EAQ83237.1 - 0.14 11.7 0.0 0.34 10.5 0.0 1.6 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.6 EAQ83237.1 - 0.16 11.7 0.0 0.33 10.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Parvo_NS1 PF01057.17 EAQ83237.1 - 0.2 10.7 0.0 0.37 9.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Folliculin PF11704.8 EAQ83238.1 - 4.8e-47 160.2 0.0 2.1e-46 158.2 0.0 1.8 2 0 0 2 2 2 1 Vesicle coat protein involved in Golgi to plasma membrane transport Y_phosphatase PF00102.27 EAQ83239.1 - 1.5e-34 119.6 0.0 7.1e-34 117.4 0.0 1.8 1 1 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 EAQ83239.1 - 0.0035 17.2 0.0 0.0064 16.3 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 EAQ83239.1 - 0.013 15.6 0.0 0.025 14.7 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 EAQ83239.1 - 0.11 12.4 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family RCC1 PF00415.18 EAQ83240.1 - 8.9e-30 103.1 12.7 1.8e-06 28.4 0.0 7.5 6 1 1 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EAQ83240.1 - 3.7e-15 55.3 20.4 2.4e-09 36.7 0.0 7.0 7 0 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat DUF1459 PF07312.11 EAQ83240.1 - 0.37 11.0 2.3 0.51 10.6 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1459) Sec34 PF04136.15 EAQ83241.1 - 9.9e-39 132.6 0.1 1.6e-38 131.9 0.1 1.3 1 0 0 1 1 1 1 Sec34-like family CENP-B_dimeris PF09026.10 EAQ83241.1 - 2.4 8.6 8.8 8.5 6.8 8.8 1.9 1 0 0 1 1 1 0 Centromere protein B dimerisation domain CDO_I PF05995.12 EAQ83242.1 - 0.02 14.2 0.1 0.037 13.3 0.1 1.5 1 0 0 1 1 1 0 Cysteine dioxygenase type I DUF3568 PF12092.8 EAQ83242.1 - 0.037 14.1 0.0 0.075 13.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3568) Beta_helix PF13229.6 EAQ83246.1 - 2.3e-05 24.3 24.3 0.0017 18.2 18.4 2.3 1 1 1 2 2 2 2 Right handed beta helix region VCBS PF13517.6 EAQ83248.1 - 9.4e-31 106.2 47.1 3e-15 56.6 1.9 7.9 2 2 7 9 9 9 9 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Lipase_GDSL_2 PF13472.6 EAQ83248.1 - 9e-16 58.8 1.9 1.1e-15 58.4 0.6 1.9 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family TcdB_toxin_midN PF12256.8 EAQ83248.1 - 7.4e-08 31.9 5.8 0.3 10.4 0.0 6.5 5 2 3 8 8 8 3 Insecticide toxin TcdB middle/N-terminal region Lipase_GDSL PF00657.22 EAQ83248.1 - 8.4e-08 32.4 0.0 1.3e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase FG-GAP PF01839.23 EAQ83248.1 - 1.3e-06 28.4 29.9 0.018 15.2 0.6 6.8 6 0 0 6 6 6 4 FG-GAP repeat Lipase_GDSL_3 PF14606.6 EAQ83248.1 - 0.0072 16.5 0.1 0.043 14.0 0.0 2.0 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family RVT_1 PF00078.27 EAQ83249.1 - 1.1e-37 129.8 0.1 6.6e-37 127.2 0.0 2.2 3 0 0 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 EAQ83249.1 - 4.3e-25 87.9 0.1 2e-24 85.7 0.0 2.3 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 EAQ83249.1 - 9.8e-05 22.0 0.1 0.00025 20.7 0.1 1.7 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-CCHC PF00098.23 EAQ83249.1 - 0.0097 16.0 2.5 0.0097 16.0 2.5 2.4 2 0 0 2 2 1 1 Zinc knuckle Herpes_UL6 PF01763.16 EAQ83249.1 - 0.032 12.8 1.8 0.054 12.0 1.8 1.2 1 0 0 1 1 1 0 Herpesvirus UL6 like CASP_C PF08172.12 EAQ83249.1 - 0.042 13.2 2.6 0.099 12.0 2.6 1.5 1 0 0 1 1 1 0 CASP C terminal SlyX PF04102.12 EAQ83249.1 - 0.053 14.1 7.1 0.18 12.4 6.6 2.3 1 1 0 1 1 1 0 SlyX DUF948 PF06103.11 EAQ83249.1 - 0.066 13.5 0.6 0.28 11.5 0.6 2.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) zf-RVT PF13966.6 EAQ83249.1 - 0.56 11.0 0.0 0.56 11.0 0.0 2.6 3 0 0 3 3 2 0 zinc-binding in reverse transcriptase TEX13 PF15186.6 EAQ83249.1 - 2.5 7.8 5.5 10 5.8 5.5 2.1 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family ADIP PF11559.8 EAQ83249.1 - 4.4 7.4 12.0 0.22 11.6 5.7 2.0 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Syntaxin-6_N PF09177.11 EAQ83249.1 - 4.6 7.9 5.7 9.3 6.9 1.8 3.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Mito_carr PF00153.27 EAQ83251.1 - 1.4e-53 178.8 1.4 1.7e-20 72.7 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein RINT1_TIP1 PF04437.13 EAQ83252.1 - 1.9e-164 548.3 0.0 1e-163 545.9 0.0 1.9 1 1 0 1 1 1 1 RINT-1 / TIP-1 family TPR_MLP1_2 PF07926.12 EAQ83252.1 - 0.0054 16.8 2.1 0.014 15.4 2.1 1.7 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein DUF4164 PF13747.6 EAQ83252.1 - 0.0072 16.6 4.4 0.014 15.6 3.4 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF4164) DHR10 PF18595.1 EAQ83252.1 - 0.0095 16.0 0.9 0.025 14.6 0.9 1.7 1 0 0 1 1 1 1 Designed helical repeat protein 10 domain CRISPR_Cse2 PF09485.10 EAQ83252.1 - 0.015 15.8 1.0 0.05 14.1 0.2 2.3 2 0 0 2 2 2 0 CRISPR-associated protein Cse2 (CRISPR_cse2) UPF0242 PF06785.11 EAQ83252.1 - 0.21 11.7 3.1 0.45 10.6 3.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus ADIP PF11559.8 EAQ83252.1 - 0.23 11.6 1.8 0.65 10.1 1.8 1.8 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF4472 PF14739.6 EAQ83252.1 - 1.3 9.8 4.3 1 10.1 1.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4472) DUF155 PF02582.14 EAQ83253.1 - 6.3e-42 143.6 0.0 9.3e-42 143.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 SHMT PF00464.19 EAQ83255.1 - 7.6e-207 686.7 0.0 9.4e-207 686.3 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.21 EAQ83255.1 - 0.00033 20.0 0.0 0.00076 18.7 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 EAQ83255.1 - 0.011 15.0 0.0 0.026 13.8 0.0 1.7 1 1 0 1 1 1 0 Beta-eliminating lyase KKLCAg1 PF15204.6 EAQ83255.1 - 0.046 13.8 0.0 0.088 12.9 0.0 1.4 1 0 0 1 1 1 0 Kita-kyushu lung cancer antigen 1 Cys_Met_Meta_PP PF01053.20 EAQ83255.1 - 0.06 11.9 0.0 0.099 11.1 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Bromodomain PF00439.25 EAQ83256.1 - 1.3e-18 66.8 0.1 2.8e-18 65.8 0.1 1.5 1 0 0 1 1 1 1 Bromodomain Bromo_TP PF07524.13 EAQ83256.1 - 4.9e-09 36.1 0.0 4e-08 33.2 0.0 2.2 1 1 0 1 1 1 1 Bromodomain associated PBP1_TM PF14812.6 EAQ83256.1 - 0.72 10.3 22.1 0.93 9.9 13.3 3.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal VanZ PF04892.12 EAQ83257.1 - 2.5e-09 37.9 1.7 3.4e-09 37.4 1.7 1.2 1 0 0 1 1 1 1 VanZ like family Ferric_reduct PF01794.19 EAQ83258.1 - 6.8e-21 74.7 5.3 8.9e-21 74.3 3.6 2.0 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 EAQ83258.1 - 1.4e-17 64.2 0.0 2.3e-17 63.5 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 EAQ83258.1 - 1.7e-06 28.6 0.1 0.0025 18.4 0.1 2.6 2 1 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_8 PF08022.12 EAQ83258.1 - 1.4e-05 25.1 0.0 6.5e-05 23.0 0.0 2.1 1 1 0 1 1 1 1 FAD-binding domain DUF4405 PF14358.6 EAQ83258.1 - 2.4 8.8 5.7 4.9 7.8 0.4 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4405) FMO-like PF00743.19 EAQ83259.1 - 8.2e-12 44.3 0.0 1.5e-11 43.5 0.0 1.4 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EAQ83259.1 - 2.6e-10 40.1 0.0 6.6e-10 38.7 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EAQ83259.1 - 1.1e-08 34.7 0.0 2.4e-08 33.6 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EAQ83259.1 - 5.6e-06 25.7 0.0 4e-05 22.9 0.0 1.9 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 EAQ83259.1 - 0.00038 20.6 0.0 0.0021 18.3 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Imm75 PF15660.6 EAQ83259.1 - 0.081 13.2 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 Putative Immunity protein 75 Osmo_MPGsynth PF09488.10 EAQ83259.1 - 0.12 11.1 0.0 0.18 10.5 0.0 1.2 1 0 0 1 1 1 0 Mannosyl-3-phosphoglycerate synthase (osmo_MPGsynth) DAO PF01266.24 EAQ83259.1 - 0.23 11.0 2.0 4.6 6.7 0.0 2.3 1 1 0 2 2 2 0 FAD dependent oxidoreductase TPR_10 PF13374.6 EAQ83260.1 - 2.3e-65 214.8 0.0 3.4e-12 45.8 0.0 7.2 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_12 PF13424.6 EAQ83260.1 - 2.4e-62 207.2 1.7 2.7e-14 53.2 0.0 5.4 1 1 4 5 5 5 5 Tetratricopeptide repeat TPR_7 PF13176.6 EAQ83260.1 - 2.4e-25 86.6 0.1 0.00042 20.1 0.0 6.0 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_2 PF07719.17 EAQ83260.1 - 7.9e-14 50.6 0.1 0.48 10.7 0.0 5.9 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 EAQ83260.1 - 7.3e-12 45.7 0.0 0.024 15.3 0.0 5.8 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 EAQ83260.1 - 7.7e-12 44.5 0.0 0.87 9.5 0.0 5.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_MalT PF17874.1 EAQ83260.1 - 4.9e-10 39.3 4.0 1e-08 35.0 3.3 2.3 1 1 1 2 2 2 1 MalT-like TPR region TPR_19 PF14559.6 EAQ83260.1 - 9.6e-10 38.8 0.0 0.025 15.1 0.0 4.8 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_4 PF07721.14 EAQ83260.1 - 4.2e-09 36.2 0.0 12 6.9 0.0 6.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.6 EAQ83260.1 - 2.9e-08 33.5 1.5 0.74 10.3 0.0 6.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 EAQ83260.1 - 8.1e-08 32.5 3.0 8.5 7.5 0.0 7.0 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_8 PF13181.6 EAQ83260.1 - 7.4e-07 28.9 0.4 7.1 7.1 0.0 5.1 5 0 0 5 5 4 1 Tetratricopeptide repeat NB-ARC PF00931.22 EAQ83260.1 - 1.2e-05 24.6 0.0 0.12 11.5 0.0 2.5 1 1 1 2 2 2 2 NB-ARC domain PIF1 PF05970.14 EAQ83260.1 - 1.6e-05 24.3 0.2 0.00043 19.6 0.0 2.3 2 1 0 2 2 2 1 PIF1-like helicase TPR_5 PF12688.7 EAQ83260.1 - 4e-05 23.8 0.0 12 6.2 0.0 4.4 1 1 3 4 4 4 0 Tetratrico peptide repeat UvrD_C_2 PF13538.6 EAQ83260.1 - 0.00031 20.5 0.0 0.00083 19.1 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Ses_B PF17046.5 EAQ83260.1 - 0.00041 20.2 1.0 0.00096 19.1 1.0 1.7 1 0 0 1 1 1 1 SesB domain on fungal death-pathway protein PPR PF01535.20 EAQ83260.1 - 0.00059 19.9 0.5 32 5.1 0.0 5.1 5 0 0 5 5 5 0 PPR repeat Herpes_Helicase PF02689.14 EAQ83260.1 - 0.0017 16.4 0.0 0.0028 15.7 0.0 1.2 1 0 0 1 1 1 1 Helicase TPR_6 PF13174.6 EAQ83260.1 - 0.0052 17.3 2.2 1.2e+02 3.6 0.1 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat AAA_25 PF13481.6 EAQ83260.1 - 0.0074 15.9 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain RPN6_N PF18055.1 EAQ83260.1 - 0.017 15.5 1.1 4.4 7.7 0.0 3.1 2 1 1 3 3 3 0 26S proteasome regulatory subunit RPN6 N-terminal domain Ntox35 PF15534.6 EAQ83260.1 - 0.028 14.9 0.7 62 4.1 0.0 4.5 5 0 0 5 5 5 0 Bacterial toxin 35 TPR_3 PF07720.12 EAQ83260.1 - 0.14 12.2 0.0 47 4.1 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Mannosyl_trans3 PF11051.8 EAQ83261.1 - 2.4e-44 151.7 0.0 1.9e-27 96.4 0.0 2.4 1 1 1 2 2 2 2 Mannosyltransferase putative Peptidase_S10 PF00450.22 EAQ83262.1 - 1.1e-62 212.8 0.0 4.3e-55 187.8 0.0 2.2 2 1 0 2 2 2 2 Serine carboxypeptidase RTA1 PF04479.13 EAQ83263.1 - 3e-61 206.6 9.0 4.6e-61 206.0 9.0 1.3 1 0 0 1 1 1 1 RTA1 like protein P5-ATPase PF12409.8 EAQ83263.1 - 0.075 13.1 2.8 0.16 12.0 2.8 1.5 1 0 0 1 1 1 0 P5-type ATPase cation transporter RRM_1 PF00076.22 EAQ83264.1 - 1.4e-08 34.4 0.0 2.4e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EAQ83264.1 - 0.07 12.7 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RF-1 PF00472.20 EAQ83265.1 - 0.00011 22.1 1.2 0.00012 22.0 1.2 1.1 1 0 0 1 1 1 1 RF-1 domain GNAT_acetyltr_2 PF13718.6 EAQ83266.1 - 5.4e-96 320.4 0.0 9.5e-96 319.6 0.0 1.4 1 0 0 1 1 1 1 GNAT acetyltransferase 2 tRNA_bind_2 PF13725.6 EAQ83266.1 - 1.2e-76 257.5 0.0 2.1e-76 256.7 0.0 1.4 1 0 0 1 1 1 1 Possible tRNA binding domain Helicase_RecD PF05127.14 EAQ83266.1 - 2.2e-64 216.6 0.0 1e-63 214.4 0.0 2.1 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.11 EAQ83266.1 - 4.8e-33 113.0 0.0 1.1e-32 111.8 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) AAA_22 PF13401.6 EAQ83266.1 - 0.00066 20.0 0.0 0.25 11.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 EAQ83266.1 - 0.00066 19.4 0.1 0.083 12.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain Acetyltransf_1 PF00583.25 EAQ83266.1 - 0.1 12.8 0.0 1.6 8.9 0.0 2.5 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family Pkinase PF00069.25 EAQ83267.1 - 1e-52 179.1 0.0 2.6e-44 151.6 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ83267.1 - 2.9e-20 72.7 0.0 7.4e-20 71.3 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EAQ83267.1 - 4.2e-05 22.5 0.0 6.5e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EAQ83267.1 - 0.00012 21.5 0.0 0.0002 20.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EAQ83267.1 - 0.0004 20.4 0.1 0.0006 19.8 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EAQ83267.1 - 0.0051 16.2 0.0 0.0074 15.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like PAP2_3 PF14378.6 EAQ83268.1 - 2.6e-25 89.2 12.5 5e-25 88.3 12.5 1.5 1 0 0 1 1 1 1 PAP2 superfamily PAP2 PF01569.21 EAQ83268.1 - 2.4e-09 37.1 6.0 2.4e-09 37.1 6.0 2.3 1 1 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.6 EAQ83268.1 - 3.1 8.4 7.5 1.9 9.1 1.8 2.7 2 1 0 2 2 2 0 PAP2 superfamily C-terminal ExoD PF06055.12 EAQ83268.1 - 6.6 6.1 12.6 7.4 5.9 3.4 2.3 2 0 0 2 2 2 0 Exopolysaccharide synthesis, ExoD RNA_polI_A34 PF08208.11 EAQ83269.1 - 0.0023 18.1 0.0 0.0023 18.1 0.0 6.1 3 2 1 4 4 4 1 DNA-directed RNA polymerase I subunit RPA34.5 CLP1_P PF16575.5 EAQ83270.1 - 1.6e-18 67.2 0.0 2.6e-18 66.5 0.0 1.2 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop Cys_rich_KTR PF14205.6 EAQ83270.1 - 0.18 11.6 0.0 0.32 10.8 0.0 1.4 1 0 0 1 1 1 0 Cysteine-rich KTR Glyco_hydro_61 PF03443.14 EAQ83271.1 - 9.9e-15 55.0 0.1 1.2e-14 54.8 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 MFS_1 PF07690.16 EAQ83273.1 - 2.1e-19 69.7 14.5 2.1e-19 69.7 14.5 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily VIT1 PF01988.19 EAQ83273.1 - 1.3 8.8 7.1 7.2 6.4 3.2 2.8 2 1 0 2 2 2 0 VIT family Glyco_hydro_3_C PF01915.22 EAQ83274.1 - 4.9e-48 163.8 0.0 8.2e-48 163.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EAQ83274.1 - 6.6e-27 94.7 0.0 1.4e-25 90.4 0.0 2.1 1 1 1 2 2 2 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EAQ83274.1 - 4.8e-15 55.4 0.1 8.7e-15 54.6 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Lgl_C PF08596.10 EAQ83275.1 - 6.3e-65 219.4 0.0 1.6e-64 218.1 0.0 1.7 2 0 0 2 2 2 1 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.32 EAQ83275.1 - 0.00012 22.8 6.6 0.037 14.9 0.0 5.5 7 0 0 7 7 7 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAQ83275.1 - 0.00012 22.3 0.0 0.19 12.0 0.0 4.1 4 1 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 EAQ83275.1 - 0.0019 17.8 0.2 1.3 8.6 0.0 2.8 2 0 0 2 2 2 2 PQQ-like domain ArgoL2 PF16488.5 EAQ83276.1 - 3.3e-12 46.5 0.1 1.4e-11 44.5 0.1 2.1 2 0 0 2 2 2 1 Argonaute linker 2 domain PAZ PF02170.22 EAQ83276.1 - 6.1e-11 42.3 0.0 1e-10 41.6 0.0 1.3 1 0 0 1 1 1 1 PAZ domain Piwi PF02171.17 EAQ83276.1 - 3.9e-08 32.9 0.0 7.8e-08 31.9 0.0 1.4 1 0 0 1 1 1 1 Piwi domain ArgoMid PF16487.5 EAQ83276.1 - 1.7e-07 31.4 0.0 1.9e-06 28.1 0.0 2.3 2 0 0 2 2 2 1 Mid domain of argonaute ArgoL1 PF08699.10 EAQ83276.1 - 2.9e-05 23.6 0.1 6.7e-05 22.5 0.1 1.7 1 0 0 1 1 1 1 Argonaute linker 1 domain Suf PF05843.14 EAQ83277.1 - 5.5e-97 325.3 3.6 5.3e-92 309.0 0.0 3.7 3 2 2 5 5 5 2 Suppressor of forked protein (Suf) HAT PF02184.16 EAQ83277.1 - 0.021 14.8 0.1 0.36 10.8 0.1 2.6 2 0 0 2 2 2 0 HAT (Half-A-TPR) repeat TPR_14 PF13428.6 EAQ83277.1 - 0.038 14.8 4.0 0.083 13.8 0.2 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat ASF1_hist_chap PF04729.13 EAQ83278.1 - 5.9e-72 240.6 0.0 8.7e-72 240.1 0.0 1.3 1 0 0 1 1 1 1 ASF1 like histone chaperone Cwf_Cwc_15 PF04889.12 EAQ83278.1 - 0.14 11.8 5.5 0.18 11.5 5.5 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nrap_D5 PF17406.2 EAQ83279.1 - 5e-59 198.7 1.1 1.4e-58 197.2 1.0 1.8 2 0 0 2 2 2 1 Nrap protein PAP/OAS1-like domain 5 Nrap_D2 PF17403.2 EAQ83279.1 - 5.6e-50 169.0 0.3 6.6e-47 159.1 0.0 2.4 2 0 0 2 2 2 2 Nrap protein PAP/OAS-like domain Nrap PF03813.14 EAQ83279.1 - 1.3e-43 148.7 0.0 2.5e-43 147.7 0.0 1.5 1 0 0 1 1 1 1 Nrap protein domain 1 Nrap_D4 PF17405.2 EAQ83279.1 - 4.2e-41 140.7 0.1 1.3e-36 126.0 0.0 2.3 1 1 1 2 2 2 2 Nrap protein nucleotidyltransferase domain 4 Nrap_D3 PF17404.2 EAQ83279.1 - 6.6e-41 140.1 0.0 1.3e-40 139.1 0.0 1.5 1 0 0 1 1 1 1 Nrap protein domain 3 Nrap_D6 PF17407.2 EAQ83279.1 - 1.5e-39 135.3 0.0 9e-39 132.8 0.0 2.3 2 0 0 2 2 2 1 Nrap protein domain 6 OAS1_C PF10421.9 EAQ83279.1 - 0.036 13.5 0.1 0.07 12.6 0.1 1.4 1 0 0 1 1 1 0 2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus TPR_16 PF13432.6 EAQ83280.1 - 2.5e-35 120.9 49.5 2.1e-09 37.9 0.2 11.3 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_2 PF07719.17 EAQ83280.1 - 5.4e-32 107.3 46.3 0.0014 18.5 0.0 15.6 16 0 0 16 16 13 10 Tetratricopeptide repeat TPR_1 PF00515.28 EAQ83280.1 - 2e-27 93.9 26.1 0.00015 21.4 0.0 13.9 13 1 0 13 13 13 7 Tetratricopeptide repeat TPR_14 PF13428.6 EAQ83280.1 - 7.1e-25 85.6 45.2 0.0009 19.9 0.1 14.4 12 3 2 14 14 12 6 Tetratricopeptide repeat TPR_19 PF14559.6 EAQ83280.1 - 4e-22 78.5 36.7 9.5e-08 32.4 0.7 10.9 10 1 1 11 11 11 5 Tetratricopeptide repeat TPR_17 PF13431.6 EAQ83280.1 - 5.9e-21 73.3 10.9 0.69 10.4 0.0 13.2 13 0 0 13 13 13 3 Tetratricopeptide repeat TPR_8 PF13181.6 EAQ83280.1 - 3.3e-19 67.4 36.9 0.16 12.3 0.5 13.7 15 0 0 15 15 12 6 Tetratricopeptide repeat TPR_11 PF13414.6 EAQ83280.1 - 8.6e-14 50.9 34.6 0.019 14.7 0.0 10.5 10 1 1 11 11 10 5 TPR repeat TPR_12 PF13424.6 EAQ83280.1 - 3.2e-11 43.3 56.6 0.00067 19.9 0.1 14.0 12 3 2 15 15 13 4 Tetratricopeptide repeat TPR_6 PF13174.6 EAQ83280.1 - 1.8e-09 37.6 17.9 1.3 9.9 0.0 11.7 12 0 0 12 12 10 2 Tetratricopeptide repeat TPR_7 PF13176.6 EAQ83280.1 - 3.2e-09 36.2 27.0 0.044 13.8 0.0 12.3 13 0 0 13 13 13 2 Tetratricopeptide repeat TPR_MalT PF17874.1 EAQ83280.1 - 1.9e-06 27.5 17.1 0.02 14.3 0.0 5.4 4 1 1 6 6 6 3 MalT-like TPR region TPR_9 PF13371.6 EAQ83280.1 - 8.9e-06 25.8 25.4 0.062 13.5 0.0 8.5 7 2 1 8 8 8 2 Tetratricopeptide repeat TPR_22 PF18833.1 EAQ83280.1 - 0.00017 21.7 0.0 0.0005 20.1 0.0 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EAQ83280.1 - 0.00018 21.6 17.2 0.053 13.8 0.3 7.8 9 3 2 11 11 9 1 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.6 EAQ83280.1 - 0.00055 20.0 0.6 9.6 6.4 0.1 4.8 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat Coatomer_WDAD PF04053.14 EAQ83280.1 - 0.019 14.0 0.0 0.041 12.9 0.0 1.4 1 0 0 1 1 1 0 Coatomer WD associated region HrpB1_HrpK PF09613.10 EAQ83280.1 - 0.027 14.1 0.1 3.8 7.2 0.0 3.9 4 0 0 4 4 4 0 Bacterial type III secretion protein (HrpB1_HrpK) DUF4919 PF16266.5 EAQ83280.1 - 0.053 13.5 0.1 1.1 9.2 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4919) Bclt PF15318.6 EAQ83280.1 - 0.061 13.2 0.3 3.5 7.4 0.0 2.5 2 0 0 2 2 2 0 Putative Bcl-2 like protein of testis PPTA PF01239.22 EAQ83280.1 - 0.083 12.7 0.5 7.7 6.4 0.0 3.7 4 0 0 4 4 4 0 Protein prenyltransferase alpha subunit repeat DUF3239 PF11580.8 EAQ83280.1 - 0.14 12.5 0.5 0.31 11.4 0.0 1.8 2 0 0 2 2 1 0 Protein of unknown function (DUF3239) ANAPC5 PF12862.7 EAQ83280.1 - 0.21 11.6 16.0 0.51 10.4 1.2 6.1 8 0 0 8 8 6 0 Anaphase-promoting complex subunit 5 ChAPs PF09295.10 EAQ83280.1 - 0.35 9.8 2.2 22 3.9 0.0 4.0 5 0 0 5 5 5 0 ChAPs (Chs5p-Arf1p-binding proteins) Alkyl_sulf_dimr PF14863.6 EAQ83280.1 - 0.46 11.0 4.0 0.41 11.1 0.4 3.0 3 0 0 3 3 2 0 Alkyl sulfatase dimerisation FAT PF02259.23 EAQ83280.1 - 0.83 8.8 8.3 3.9 6.6 0.5 4.4 5 1 0 6 6 6 0 FAT domain TPR_5 PF12688.7 EAQ83280.1 - 0.91 9.8 5.7 2 8.7 0.0 3.9 4 0 0 4 4 4 0 Tetratrico peptide repeat TPR_4 PF07721.14 EAQ83280.1 - 5 8.0 38.8 2.4 9.0 5.0 9.5 10 0 0 10 10 8 0 Tetratricopeptide repeat RMI1_N PF08585.12 EAQ83281.1 - 1.7e-22 80.3 0.0 2e-22 80.0 0.0 1.0 1 0 0 1 1 1 1 RecQ mediated genome instability protein BASP1 PF05466.12 EAQ83282.1 - 0.71 9.8 6.1 0.75 9.8 6.1 1.1 1 0 0 1 1 1 0 Brain acid soluble protein 1 (BASP1 protein) DUF4106 PF13388.6 EAQ83282.1 - 8.7 5.5 17.3 9.5 5.3 17.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Lactamase_B_6 PF16661.5 EAQ83283.1 - 7.4e-66 221.3 0.0 1.1e-65 220.7 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain CPSF100_C PF13299.6 EAQ83283.1 - 2.8e-42 144.8 5.8 2.6e-40 138.4 0.0 3.6 3 1 1 4 4 4 2 Cleavage and polyadenylation factor 2 C-terminal RMMBL PF07521.12 EAQ83283.1 - 2e-19 69.3 0.0 4.6e-19 68.1 0.0 1.7 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Beta-Casp PF10996.8 EAQ83283.1 - 9.5e-16 58.1 0.0 3e-15 56.5 0.0 1.8 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.27 EAQ83283.1 - 6e-05 23.1 0.0 0.00017 21.7 0.0 1.7 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EAQ83283.1 - 7.8e-05 22.3 0.0 0.00023 20.7 0.0 1.8 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Sec23_trunk PF04811.15 EAQ83284.1 - 1.8e-52 178.3 0.0 4.1e-52 177.2 0.0 1.6 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 EAQ83284.1 - 1.6e-21 76.1 0.0 2.9e-21 75.2 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 EAQ83284.1 - 1e-17 64.6 0.0 1.9e-17 63.8 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 EAQ83284.1 - 5e-15 55.3 3.3 1e-14 54.3 3.3 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 EAQ83284.1 - 1.4e-06 28.1 0.0 3.3e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat DUF2263 PF10021.9 EAQ83285.1 - 2e-08 34.8 0.0 3e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) tRNA-synt_2 PF00152.20 EAQ83286.1 - 4.4e-21 75.3 0.0 6.2e-21 74.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EAQ83286.1 - 0.0092 15.9 0.0 0.016 15.2 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Gti1_Pac2 PF09729.9 EAQ83288.1 - 1.1e-33 116.8 13.4 5.7e-32 111.3 13.4 2.7 1 1 0 1 1 1 1 Gti1/Pac2 family TFIIA PF03153.13 EAQ83288.1 - 1.2 9.1 41.0 1.7 8.5 41.0 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Coagulin PF02035.15 EAQ83289.1 - 0.088 12.7 0.2 0.1 12.5 0.2 1.1 1 0 0 1 1 1 0 Coagulin Linker_histone PF00538.19 EAQ83290.1 - 1.6e-18 66.8 0.6 3.4e-18 65.8 0.2 1.7 1 1 0 1 1 1 1 linker histone H1 and H5 family RdRP_2 PF00978.21 EAQ83290.1 - 0.26 10.2 3.9 0.32 9.8 3.9 1.1 1 0 0 1 1 1 0 RNA dependent RNA polymerase TolA_bind_tri PF16331.5 EAQ83291.1 - 0.1 12.7 0.1 0.22 11.6 0.1 1.4 1 0 0 1 1 1 0 TolA binding protein trimerisation ELYS PF13934.6 EAQ83292.1 - 3e-70 236.7 0.1 3.6e-70 236.4 0.1 1.1 1 0 0 1 1 1 1 Nuclear pore complex assembly SMC_N PF02463.19 EAQ83293.1 - 6.4e-78 261.2 0.1 3.8e-77 258.7 0.1 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 EAQ83293.1 - 1.3e-23 83.5 0.0 6.2e-23 81.3 0.0 2.3 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 EAQ83293.1 - 3.6e-12 46.7 0.5 8.3e-05 22.5 0.1 3.2 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system CVNH PF08881.10 EAQ83293.1 - 1.7e-05 25.5 0.1 1.7e-05 25.5 0.1 4.0 4 2 0 4 4 4 1 CVNH domain AAA_29 PF13555.6 EAQ83293.1 - 0.00052 19.7 0.0 0.0011 18.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Tektin PF03148.14 EAQ83293.1 - 0.00095 18.0 15.2 0.00095 18.0 15.2 5.8 3 2 2 5 5 4 1 Tektin family ERM PF00769.19 EAQ83293.1 - 0.0015 18.4 24.1 0.0015 18.4 24.1 5.4 3 2 2 5 5 4 3 Ezrin/radixin/moesin family Laminin_II PF06009.12 EAQ83293.1 - 0.0041 17.1 2.9 0.0041 17.1 2.9 7.8 4 2 3 8 8 8 2 Laminin Domain II CLZ PF16526.5 EAQ83293.1 - 0.0086 16.4 6.0 0.0086 16.4 6.0 7.6 6 4 2 8 8 8 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ABC_tran PF00005.27 EAQ83293.1 - 1.7 9.2 0.0 1.7 9.2 0.0 6.5 3 2 0 4 4 2 0 ABC transporter Spc7 PF08317.11 EAQ83293.1 - 1.8 7.4 123.2 0.088 11.7 28.7 7.1 3 2 5 8 8 7 0 Spc7 kinetochore protein RPAP1_C PF08620.10 EAQ83294.1 - 1.2e-26 92.6 0.1 1.8e-26 92.0 0.1 1.3 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.10 EAQ83294.1 - 4.5e-17 61.5 1.2 9.3e-17 60.5 1.2 1.6 1 0 0 1 1 1 1 RPAP1-like, N-terminal HUN PF08729.10 EAQ83295.1 - 1.1e-07 31.7 0.3 2.1e-07 30.8 0.3 1.5 1 0 0 1 1 1 1 HPC2 and ubinuclein domain MFS_1 PF07690.16 EAQ83296.1 - 2.4e-34 118.8 40.5 2.9e-33 115.2 36.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EAQ83296.1 - 5.8e-09 35.3 4.7 5.8e-09 35.3 4.7 2.1 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 EAQ83296.1 - 6.5e-05 21.5 3.2 0.00012 20.7 3.2 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) RasGAP PF00616.19 EAQ83299.1 - 3.8e-60 203.2 0.5 1.4e-59 201.3 0.0 2.1 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 EAQ83299.1 - 2.5e-29 102.2 4.1 2.5e-29 102.2 4.1 2.7 3 0 0 3 3 3 1 RasGAP C-terminus MARVEL PF01284.23 EAQ83300.1 - 0.0069 16.4 16.5 0.0098 15.9 16.5 1.3 1 0 0 1 1 1 1 Membrane-associating domain SOG2 PF10428.9 EAQ83301.1 - 6 5.9 9.1 0.36 10.0 1.1 2.0 2 0 0 2 2 2 0 RAM signalling pathway protein DUF4775 PF16001.5 EAQ83302.1 - 1.6 8.0 6.7 1.7 8.0 6.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4775) PUF PF00806.19 EAQ83303.1 - 6.9e-11 41.2 0.0 0.56 10.0 0.0 5.9 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat Hydrolase PF00702.26 EAQ83305.1 - 0.00041 20.7 0.0 0.029 14.7 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EAQ83305.1 - 0.052 13.6 0.0 4.6 7.3 0.0 2.3 1 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase HNH PF01844.23 EAQ83306.1 - 0.0012 19.0 1.8 0.0022 18.2 1.8 1.4 1 0 0 1 1 1 1 HNH endonuclease AMMECR1 PF01871.17 EAQ83309.1 - 7.6e-29 100.4 0.0 1.1e-28 99.9 0.0 1.3 1 1 1 2 2 2 1 AMMECR1 Ras PF00071.22 EAQ83310.1 - 5.2e-36 123.7 0.0 5.9e-23 81.2 0.0 2.2 2 0 0 2 2 2 2 Ras family Roc PF08477.13 EAQ83310.1 - 7.5e-10 39.1 0.0 1.8e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 EAQ83310.1 - 0.047 13.8 0.0 0.081 13.0 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase Pyridoxal_deC PF00282.19 EAQ83312.1 - 1.4e-47 162.2 0.0 4.8e-45 153.9 0.0 2.4 2 1 1 3 3 3 2 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 EAQ83312.1 - 2.2e-05 23.6 0.0 3.2e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 EAQ83312.1 - 0.00059 19.2 0.0 0.0013 18.1 0.0 1.5 2 0 0 2 2 2 1 Beta-eliminating lyase SepSecS PF05889.13 EAQ83312.1 - 0.071 11.8 0.0 0.096 11.4 0.0 1.1 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Thi4 PF01946.17 EAQ83313.1 - 4.9e-113 376.2 0.3 6.1e-113 375.8 0.3 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 EAQ83313.1 - 3.7e-08 33.3 0.9 3.2e-06 27.0 0.5 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EAQ83313.1 - 0.0001 22.4 1.3 0.00028 21.0 1.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EAQ83313.1 - 0.00024 20.4 0.2 0.00041 19.7 0.2 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EAQ83313.1 - 0.00088 18.4 0.1 0.0014 17.8 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 EAQ83313.1 - 0.0023 18.0 0.3 0.007 16.4 0.2 1.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 EAQ83313.1 - 0.0055 15.8 2.2 0.036 13.1 0.9 2.2 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 EAQ83313.1 - 0.066 12.5 2.0 0.11 11.8 2.0 1.4 1 1 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 EAQ83313.1 - 0.1 11.3 0.4 0.15 10.7 0.4 1.3 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.27 EAQ83313.1 - 0.13 12.9 1.0 1 10.0 0.2 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EAQ83313.1 - 0.14 11.0 0.3 0.19 10.5 0.3 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox_3 PF13738.6 EAQ83313.1 - 0.17 11.1 0.5 0.27 10.4 0.5 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Questin_oxidase PF14027.6 EAQ83315.1 - 2.3e-23 83.3 0.0 2.7e-23 83.1 0.0 1.0 1 0 0 1 1 1 1 Questin oxidase-like LCCL PF03815.19 EAQ83316.1 - 4.4e-23 81.2 0.0 6.5e-23 80.7 0.0 1.2 1 0 0 1 1 1 1 LCCL domain MAM33 PF02330.16 EAQ83317.1 - 1e-75 254.4 0.5 1.2e-75 254.1 0.5 1.1 1 0 0 1 1 1 1 Mitochondrial glycoprotein UL21a PF17636.2 EAQ83317.1 - 0.0014 18.7 0.0 0.0053 16.8 0.0 1.9 2 1 0 2 2 2 1 Viral Unique Long protein 21a Tma16 PF11176.8 EAQ83318.1 - 2.3e-31 108.6 0.1 2.5e-31 108.5 0.1 1.0 1 0 0 1 1 1 1 Translation machinery-associated protein 16 SURF6 PF04935.12 EAQ83319.1 - 4.2e-50 170.3 41.5 4.2e-50 170.3 41.5 4.1 3 1 1 4 4 4 1 Surfeit locus protein 6 XPG_N PF00752.17 EAQ83319.1 - 1.3e-23 83.3 0.1 6.6e-23 81.1 0.0 2.3 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I PF00867.18 EAQ83319.1 - 8.8e-22 77.3 0.0 8.8e-22 77.3 0.0 2.9 3 0 0 3 3 3 1 XPG I-region RRP14 PF15459.6 EAQ83319.1 - 1.6e-17 63.8 1.0 1.6e-17 63.8 1.0 7.0 6 2 0 6 6 6 1 60S ribosome biogenesis protein Rrp14 5_3_exonuc PF01367.20 EAQ83319.1 - 0.03 14.9 0.0 0.03 14.9 0.0 2.8 3 0 0 3 3 3 0 5'-3' exonuclease, C-terminal SAM fold GPP34 PF05719.11 EAQ83320.1 - 8.7e-69 231.6 0.3 1e-68 231.4 0.3 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) Oxysterol_BP PF01237.18 EAQ83321.1 - 4.9e-47 160.6 0.0 5.9e-36 124.1 0.0 2.2 1 1 0 2 2 2 2 Oxysterol-binding protein CP2 PF04516.15 EAQ83323.1 - 5e-80 268.1 0.0 7.1e-80 267.6 0.0 1.2 1 0 0 1 1 1 1 CP2 transcription factor Tektin PF03148.14 EAQ83323.1 - 0.015 14.0 0.0 0.023 13.5 0.0 1.2 1 0 0 1 1 1 0 Tektin family TMF_DNA_bd PF12329.8 EAQ83323.1 - 0.053 13.5 0.1 0.1 12.6 0.1 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding eIF2A PF08662.11 EAQ83327.1 - 8.5e-30 104.1 0.0 1.6e-24 86.9 0.0 2.8 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 EAQ83327.1 - 0.016 16.1 0.0 2.9 8.9 0.0 3.2 2 1 1 3 3 3 0 WD domain, G-beta repeat DUF1754 PF08555.10 EAQ83327.1 - 5.8 7.8 9.2 0.35 11.7 3.9 1.7 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) PGA2 PF07543.12 EAQ83329.1 - 0.042 13.8 5.5 0.053 13.5 5.5 1.2 1 0 0 1 1 1 0 Protein trafficking PGA2 DUF3381 PF11861.8 EAQ83329.1 - 0.063 13.1 10.5 0.081 12.7 10.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) Nop14 PF04147.12 EAQ83329.1 - 0.13 10.4 12.0 0.13 10.4 12.0 1.0 1 0 0 1 1 1 0 Nop14-like family GREB1 PF15782.5 EAQ83329.1 - 0.22 8.6 1.9 0.24 8.5 1.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer UPF0542 PF15086.6 EAQ83329.1 - 0.24 11.4 6.0 0.37 10.7 6.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 TraV PF09676.10 EAQ83329.1 - 0.39 11.7 7.7 0.47 11.4 7.7 1.0 1 0 0 1 1 1 0 Type IV conjugative transfer system lipoprotein (TraV) FAM176 PF14851.6 EAQ83329.1 - 0.41 10.3 6.4 0.54 9.9 6.4 1.3 1 0 0 1 1 1 0 FAM176 family CCDC106 PF15794.5 EAQ83329.1 - 0.95 9.1 9.0 1.2 8.8 9.0 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 CDC45 PF02724.14 EAQ83329.1 - 1 7.6 14.7 1 7.5 14.7 1.0 1 0 0 1 1 1 0 CDC45-like protein YqfQ PF14181.6 EAQ83329.1 - 1.9 8.6 10.2 2.4 8.3 10.2 1.1 1 0 0 1 1 1 0 YqfQ-like protein SOBP PF15279.6 EAQ83329.1 - 2.2 8.8 6.7 2.5 8.6 6.7 1.0 1 0 0 1 1 1 0 Sine oculis-binding protein DUF4637 PF15470.6 EAQ83329.1 - 4.8 6.9 12.3 5.6 6.7 12.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) RR_TM4-6 PF06459.12 EAQ83329.1 - 5.7 6.7 8.8 6.1 6.6 8.8 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 EAQ83329.1 - 6.7 5.4 7.8 7 5.3 7.8 1.0 1 0 0 1 1 1 0 Presenilin DNA_pol_phi PF04931.13 EAQ83329.1 - 8.9 4.3 13.2 9.3 4.2 13.2 1.0 1 0 0 1 1 1 0 DNA polymerase phi GTP_EFTU PF00009.27 EAQ83331.1 - 7.8e-36 123.4 2.6 3.1e-34 118.2 2.6 2.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 EAQ83331.1 - 1.8e-26 92.3 0.1 4.3e-26 91.1 0.1 1.6 1 0 0 1 1 1 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 EAQ83331.1 - 2.7e-10 40.3 0.1 6.2e-10 39.2 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase IF2_N PF04760.15 EAQ83331.1 - 9.1e-09 35.0 0.0 2e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region GTP_EFTU_D2 PF03144.25 EAQ83331.1 - 3.2e-08 33.8 3.7 0.0031 17.9 0.1 3.7 3 0 0 3 3 3 2 Elongation factor Tu domain 2 RsgA_GTPase PF03193.16 EAQ83331.1 - 7.8e-06 25.9 1.3 0.0016 18.4 0.0 2.4 1 1 1 2 2 2 2 RsgA GTPase Arf PF00025.21 EAQ83331.1 - 1.1e-05 24.9 0.0 2e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family FeoB_N PF02421.18 EAQ83331.1 - 0.00016 21.2 0.1 0.00032 20.3 0.1 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B PduV-EutP PF10662.9 EAQ83331.1 - 0.00048 19.9 0.1 0.0012 18.6 0.1 1.6 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 EAQ83331.1 - 0.0018 17.7 0.2 0.0044 16.5 0.2 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 EAQ83331.1 - 0.003 17.8 0.0 0.0062 16.8 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU_D4 PF14578.6 EAQ83331.1 - 0.018 14.9 1.1 0.078 12.9 0.2 2.3 2 0 0 2 2 2 0 Elongation factor Tu domain 4 MeaB PF03308.16 EAQ83331.1 - 0.047 12.7 0.1 0.12 11.3 0.1 1.7 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_26 PF13500.6 EAQ83331.1 - 0.11 12.4 0.1 0.29 10.9 0.1 1.7 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 EAQ83331.1 - 0.65 10.0 3.2 8.6 6.4 0.0 3.4 2 1 1 3 3 3 0 Dynamin family Ribo_biogen_C PF04034.13 EAQ83332.1 - 1.8e-47 160.2 0.0 2.5e-47 159.8 0.0 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 EAQ83332.1 - 4e-11 42.5 0.5 9e-11 41.4 0.5 1.6 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI DNA_pol_phi PF04931.13 EAQ83332.1 - 3 5.8 20.0 4.3 5.3 20.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi VHS PF00790.19 EAQ83333.1 - 1.1e-43 148.5 0.0 1.2e-43 148.3 0.0 1.0 1 0 0 1 1 1 1 VHS domain AAA_16 PF13191.6 EAQ83334.1 - 1e-06 29.2 0.0 3.5e-06 27.5 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain DUF676 PF05057.14 EAQ83334.1 - 0.0049 16.4 0.0 0.01 15.4 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 EAQ83334.1 - 0.047 13.4 0.0 0.08 12.6 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein FHA PF00498.26 EAQ83335.1 - 3.4e-15 56.1 0.0 6.8e-15 55.2 0.0 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EAQ83335.1 - 0.047 14.0 0.0 0.57 10.5 0.0 2.1 1 1 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain IBR PF01485.21 EAQ83336.1 - 6.7e-21 74.3 48.3 1.2e-11 44.7 7.1 4.5 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 EAQ83336.1 - 4.1e-05 23.4 42.2 0.00043 20.1 5.2 4.6 3 1 1 4 4 4 3 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EAQ83336.1 - 0.012 15.9 7.2 0.012 15.9 7.2 4.2 2 1 1 3 3 3 0 Ring finger domain zf-C3HC4_2 PF13923.6 EAQ83336.1 - 0.035 13.9 41.1 0.11 12.3 4.9 5.0 3 1 1 4 4 4 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EAQ83336.1 - 0.13 12.4 35.5 0.033 14.2 5.6 3.9 3 1 0 3 3 3 0 RING-type zinc-finger CobA_CobO_BtuR PF02572.15 EAQ83336.1 - 0.15 12.3 0.1 0.31 11.3 0.1 1.6 1 0 0 1 1 1 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP zf-C3HC4_4 PF15227.6 EAQ83336.1 - 7.5 6.8 32.3 1.2 9.3 1.7 4.6 3 1 0 3 3 3 0 zinc finger of C3HC4-type, RING CoA_trans PF01144.23 EAQ83337.1 - 1.2e-63 214.4 0.3 7.6e-53 179.1 0.0 3.0 2 1 1 3 3 3 3 Coenzyme A transferase Redoxin PF08534.10 EAQ83338.1 - 4.6e-17 62.1 0.1 2.5e-09 37.0 0.0 2.1 1 1 1 2 2 2 2 Redoxin CAF-1_p60_C PF15512.6 EAQ83338.1 - 0.05 14.1 2.1 0.068 13.6 2.1 1.2 1 0 0 1 1 1 0 Chromatin assembly factor complex 1 subunit p60, C-terminal DASH_Dam1 PF08653.10 EAQ83339.1 - 6.5e-28 96.3 1.6 9.9e-28 95.7 1.6 1.3 1 0 0 1 1 1 1 DASH complex subunit Dam1 CRAL_TRIO PF00650.20 EAQ83340.1 - 1.1e-43 148.8 1.2 1.1e-43 148.7 0.3 1.5 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EAQ83340.1 - 1.6e-14 53.8 0.1 4.1e-14 52.5 0.1 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 EAQ83340.1 - 5.1e-06 26.7 0.0 8.6e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain MbeD_MobD PF04899.12 EAQ83340.1 - 0.14 12.3 0.2 0.28 11.3 0.2 1.4 1 0 0 1 1 1 0 MbeD/MobD like HIT PF01230.23 EAQ83341.1 - 1.2e-09 38.8 0.0 2.2e-09 37.9 0.0 1.4 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.8 EAQ83341.1 - 0.00025 21.5 0.2 0.00041 20.8 0.0 1.4 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 EAQ83341.1 - 0.15 11.9 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 PPS_PS PF02006.16 EAQ83341.1 - 0.17 11.4 0.0 0.26 10.9 0.0 1.2 1 0 0 1 1 1 0 Phosphopantothenate/pantothenate synthetase SprT-like PF10263.9 EAQ83342.1 - 1.5e-38 131.1 2.6 3.4e-38 130.0 2.6 1.6 1 0 0 1 1 1 1 SprT-like family Zn_ribbon_SprT PF17283.2 EAQ83342.1 - 8.8e-09 35.1 0.2 1.8e-08 34.1 0.2 1.5 1 0 0 1 1 1 1 SprT-like zinc ribbon domain DUF3439 PF11921.8 EAQ83342.1 - 0.018 15.0 6.1 0.034 14.1 6.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SSP160 PF06933.11 EAQ83342.1 - 0.29 9.3 9.5 0.43 8.7 9.5 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Glucan_synthase PF02364.15 EAQ83343.1 - 0 1105.2 4.0 1.2e-217 724.9 1.4 2.2 1 1 1 2 2 2 2 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 EAQ83343.1 - 6.1e-44 149.5 0.6 1.8e-43 147.9 0.6 1.9 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Aminotran_1_2 PF00155.21 EAQ83344.1 - 4.8e-36 124.7 0.0 6e-36 124.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II BtpA PF03437.15 EAQ83344.1 - 0.0083 15.6 0.2 0.014 14.9 0.2 1.3 1 0 0 1 1 1 1 BtpA family Cys_Met_Meta_PP PF01053.20 EAQ83344.1 - 0.011 14.3 0.0 0.019 13.5 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme OKR_DC_1 PF01276.20 EAQ83344.1 - 0.032 13.0 0.0 0.25 10.0 0.0 2.3 2 1 0 2 2 2 0 Orn/Lys/Arg decarboxylase, major domain RVT_1 PF00078.27 EAQ83345.1 - 5.3e-06 26.1 0.0 8e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 EAQ83345.1 - 0.1 13.3 0.0 0.28 11.9 0.0 1.7 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase Xan_ur_permease PF00860.20 EAQ83346.1 - 6.1e-64 216.1 31.4 8.7e-63 212.3 31.4 2.0 1 1 0 1 1 1 1 Permease family MARVEL PF01284.23 EAQ83347.1 - 0.23 11.5 20.0 0.34 10.9 20.0 1.2 1 0 0 1 1 1 0 Membrane-associating domain Tetraspanin PF00335.20 EAQ83347.1 - 0.36 10.5 9.6 2.7 7.6 3.7 2.2 1 1 1 2 2 2 0 Tetraspanin family DUF4293 PF14126.6 EAQ83347.1 - 2.1 8.6 9.3 0.64 10.3 5.5 1.8 1 1 0 2 2 2 0 Domain of unknown function (DUF4293) 7TMR-DISM_7TM PF07695.11 EAQ83347.1 - 6.3 6.6 19.8 5.2 6.9 13.6 2.1 1 1 0 2 2 2 0 7TM diverse intracellular signalling DUF1652 PF07865.11 EAQ83348.1 - 0.076 12.8 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1652) DUF3246 PF11596.8 EAQ83349.1 - 0.075 12.5 0.3 0.17 11.3 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) PIF1 PF05970.14 EAQ83351.1 - 5.4e-22 78.5 1.2 1.1e-18 67.6 0.0 2.2 2 0 0 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 EAQ83351.1 - 8.9e-08 32.1 0.0 7.1e-07 29.1 0.0 2.5 1 1 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 EAQ83351.1 - 7.3e-07 28.9 0.0 0.069 13.0 0.0 3.3 3 0 0 3 3 3 2 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 EAQ83351.1 - 0.0011 19.3 0.0 0.003 17.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF4928 PF16280.5 EAQ83351.1 - 0.11 11.7 0.0 7.9 5.6 0.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4928) Pex14_N PF04695.13 EAQ83351.1 - 4.3 8.0 5.7 8.7 7.0 0.3 2.8 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Ank_2 PF12796.7 EAQ83352.1 - 7.2e-106 347.0 30.4 1.4e-17 64.1 0.3 7.4 3 1 7 10 10 9 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAQ83352.1 - 2.5e-55 184.2 3.3 3.4e-07 30.7 0.0 11.1 1 1 10 11 11 11 10 Ankyrin repeats (many copies) Ank PF00023.30 EAQ83352.1 - 1.4e-50 167.6 22.8 0.0021 18.5 0.1 12.5 12 0 0 12 12 12 10 Ankyrin repeat Ank_5 PF13857.6 EAQ83352.1 - 3.7e-45 151.4 0.8 4e-05 23.8 0.0 11.0 1 1 9 10 10 10 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAQ83352.1 - 7.1e-36 118.2 1.2 1 10.1 0.0 12.0 11 0 0 11 11 11 11 Ankyrin repeat NACHT PF05729.12 EAQ83352.1 - 2.8e-10 40.4 0.1 6.6e-10 39.2 0.1 1.6 1 0 0 1 1 1 1 NACHT domain PNP_UDP_1 PF01048.20 EAQ83352.1 - 2e-09 37.1 0.6 1.5e-08 34.2 0.3 2.6 2 1 0 2 2 2 1 Phosphorylase superfamily AAA_16 PF13191.6 EAQ83352.1 - 1.4e-05 25.6 2.7 2.8e-05 24.6 0.6 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EAQ83352.1 - 0.0011 19.2 0.0 0.0046 17.2 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 EAQ83352.1 - 0.0044 17.1 0.0 0.67 10.0 0.0 3.5 3 2 0 3 3 2 1 AAA domain UPF0051 PF01458.17 EAQ83352.1 - 0.0047 16.6 7.9 10 5.8 0.2 6.2 4 1 2 7 7 7 3 Uncharacterized protein family (UPF0051) Focal_AT PF03623.13 EAQ83352.1 - 0.0096 15.9 0.7 0.029 14.3 0.1 2.2 2 0 0 2 2 1 1 Focal adhesion targeting region ATPase_2 PF01637.18 EAQ83352.1 - 0.014 15.3 0.0 0.029 14.3 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea NB-ARC PF00931.22 EAQ83352.1 - 0.031 13.5 0.0 0.077 12.2 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain ResIII PF04851.15 EAQ83352.1 - 0.17 11.9 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Enkurin PF13864.6 EAQ83352.1 - 0.18 12.2 0.7 0.84 10.1 0.1 2.3 2 0 0 2 2 2 0 Calmodulin-binding HicA_toxin PF07927.12 EAQ83352.1 - 1.5 8.9 15.8 1.4e+02 2.6 0.0 8.3 10 0 0 10 10 10 0 HicA toxin of bacterial toxin-antitoxin, MAP17 PF15807.5 EAQ83353.1 - 0.14 12.3 0.0 0.26 11.5 0.0 1.4 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 CoA_trans PF01144.23 EAQ83354.1 - 1.4e-83 279.6 1.4 2.9e-42 144.5 0.0 2.9 2 1 1 3 3 3 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.6 EAQ83354.1 - 0.00015 21.7 0.2 0.00037 20.4 0.2 1.6 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain Zn_clus PF00172.18 EAQ83356.1 - 0.0017 18.4 8.0 0.0046 17.0 8.0 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MutS_V PF00488.21 EAQ83357.1 - 2.5e-67 226.6 0.1 6.4e-67 225.2 0.1 1.7 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EAQ83357.1 - 3.1e-41 141.7 0.0 6.5e-41 140.7 0.0 1.6 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 EAQ83357.1 - 2.1e-33 114.9 0.0 6.3e-33 113.4 0.0 1.9 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 EAQ83357.1 - 2.1e-14 53.9 0.0 7.5e-14 52.2 0.0 2.0 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.18 EAQ83357.1 - 6.4e-12 45.7 0.7 1.3e-11 44.6 0.7 1.6 1 0 0 1 1 1 1 MutS family domain IV AAA_23 PF13476.6 EAQ83357.1 - 0.0016 19.0 0.3 0.012 16.2 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_27 PF13514.6 EAQ83357.1 - 0.031 13.9 0.1 0.19 11.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 EAQ83357.1 - 0.042 13.6 0.0 0.091 12.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.6 EAQ83357.1 - 0.1 12.4 2.4 0.11 12.3 0.2 2.1 2 1 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 EAQ83357.1 - 0.15 11.8 0.5 2.9 7.5 0.1 2.4 3 0 0 3 3 3 0 AAA ATPase domain SPT6_acidic PF14632.6 EAQ83357.1 - 5.6 7.6 10.2 3.9 8.1 6.9 2.4 1 1 1 2 2 2 0 Acidic N-terminal SPT6 DUF1948 PF09185.10 EAQ83358.1 - 0.11 12.3 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1948) Totivirus_coat PF05518.11 EAQ83359.1 - 3.7 5.5 9.8 5.6 4.9 9.8 1.3 1 0 0 1 1 1 0 Totivirus coat protein APH PF01636.23 EAQ83361.1 - 2.3e-08 34.3 0.0 6e-08 32.9 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EAQ83361.1 - 8.7e-05 22.2 0.0 0.00013 21.6 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Fe_hyd_SSU PF02256.17 EAQ83361.1 - 0.054 13.6 2.0 0.8 9.8 0.0 2.5 2 0 0 2 2 2 0 Iron hydrogenase small subunit zf-MYND PF01753.18 EAQ83362.1 - 6.2e-09 35.8 4.2 6.2e-09 35.8 4.2 1.9 2 0 0 2 2 2 1 MYND finger zf-Mss51 PF13824.6 EAQ83362.1 - 0.064 13.4 6.7 0.059 13.5 2.5 2.8 3 0 0 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 Filo_glycop PF01611.16 EAQ83362.1 - 0.19 10.7 0.1 0.28 10.1 0.1 1.2 1 0 0 1 1 1 0 Filovirus glycoprotein HET PF06985.11 EAQ83363.1 - 1.3e-29 103.4 0.0 2.1e-29 102.8 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ARF7EP_C PF14949.6 EAQ83363.1 - 0.2 12.3 1.5 0.54 10.9 1.5 1.7 1 0 0 1 1 1 0 ARF7 effector protein C-terminus Beta-lactamase PF00144.24 EAQ83364.1 - 3.6e-22 79.1 0.1 5.3e-22 78.5 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase Tyrosinase PF00264.20 EAQ83365.1 - 5.8e-51 173.9 0.0 7.1e-51 173.6 0.0 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase Dimer_Tnp_hAT PF05699.14 EAQ83366.1 - 5.6e-18 64.5 0.2 1.1e-17 63.6 0.2 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region MULE PF10551.9 EAQ83367.1 - 2.6e-22 79.1 0.0 4.6e-22 78.3 0.0 1.4 1 0 0 1 1 1 1 MULE transposase domain FAR1 PF03101.15 EAQ83367.1 - 0.059 14.1 0.1 0.11 13.2 0.1 1.5 1 0 0 1 1 1 0 FAR1 DNA-binding domain Lactonase PF10282.9 EAQ83369.1 - 0.0068 15.7 0.2 0.085 12.1 0.2 2.1 1 1 1 2 2 2 2 Lactonase, 7-bladed beta-propeller SGL PF08450.12 EAQ83369.1 - 0.0093 15.6 0.1 0.023 14.3 0.1 1.5 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region SBBP PF06739.11 EAQ83369.1 - 0.074 13.1 0.4 0.36 10.9 0.0 2.3 2 0 0 2 2 2 0 Beta-propeller repeat GSDH PF07995.11 EAQ83369.1 - 0.1 11.9 3.4 1 8.6 0.1 2.7 3 1 0 3 3 3 0 Glucose / Sorbosone dehydrogenase MFS_1 PF07690.16 EAQ83370.1 - 2.4e-31 108.9 51.9 1.4e-19 70.2 27.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EAQ83370.1 - 5.2e-14 52.0 29.4 1.3e-08 34.1 11.1 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter Diphthamide_syn PF01866.17 EAQ83371.1 - 4.1e-46 157.8 0.0 5.6e-46 157.4 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein Fasciclin PF02469.22 EAQ83373.1 - 5.9e-36 123.5 0.4 7.7e-27 94.0 0.2 2.3 2 0 0 2 2 2 2 Fasciclin domain Pro_CA PF00484.19 EAQ83374.1 - 8.9e-52 175.5 0.1 1.2e-51 175.1 0.1 1.2 1 0 0 1 1 1 1 Carbonic anhydrase NACHT PF05729.12 EAQ83375.1 - 7.9e-13 48.7 0.7 2.6e-10 40.5 0.0 2.1 2 0 0 2 2 2 2 NACHT domain AAA_22 PF13401.6 EAQ83375.1 - 1.5e-05 25.3 0.5 0.00017 21.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 EAQ83375.1 - 2.1e-05 25.0 1.1 0.0079 16.6 0.1 3.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EAQ83375.1 - 0.00027 21.4 0.3 0.0015 18.9 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain KAP_NTPase PF07693.14 EAQ83375.1 - 0.00045 19.5 1.9 0.17 11.1 0.2 3.0 2 1 0 2 2 2 2 KAP family P-loop domain PAE PF03283.13 EAQ83375.1 - 0.067 12.3 0.1 0.091 11.9 0.1 1.2 1 0 0 1 1 1 0 Pectinacetylesterase RuvB_N PF05496.12 EAQ83375.1 - 0.12 12.1 0.0 0.31 10.8 0.0 1.7 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Snapin_Pallidin PF14712.6 EAQ83375.1 - 0.15 12.5 1.4 6.7 7.2 0.2 2.8 2 1 1 3 3 3 0 Snapin/Pallidin DUF1319 PF07028.11 EAQ83375.1 - 0.83 9.9 3.7 14 6.0 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1319) Ank_2 PF12796.7 EAQ83376.1 - 3.1e-48 162.3 0.0 8.3e-15 55.2 0.0 4.5 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAQ83376.1 - 9.5e-28 93.2 0.4 0.00012 22.3 0.0 7.9 8 0 0 8 8 8 4 Ankyrin repeat Ank_4 PF13637.6 EAQ83376.1 - 3.9e-27 94.3 1.1 2.3e-07 31.2 0.0 6.4 2 1 5 7 7 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAQ83376.1 - 5.7e-25 87.1 6.1 3.3e-07 30.4 0.0 6.7 1 1 6 7 7 7 7 Ankyrin repeats (many copies) Ank PF00023.30 EAQ83376.1 - 1e-22 79.5 2.3 0.00049 20.4 0.0 7.9 8 0 0 8 8 8 6 Ankyrin repeat NMT1 PF09084.11 EAQ83377.1 - 2.6e-78 262.9 0.0 3.6e-78 262.4 0.0 1.2 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 EAQ83377.1 - 1.8e-06 27.8 0.1 0.22 11.2 0.0 3.6 3 1 1 4 4 4 2 NMT1-like family FMN_red PF03358.15 EAQ83377.1 - 0.065 13.0 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 NADPH-dependent FMN reductase AAA PF00004.29 EAQ83379.1 - 5.7e-37 127.1 0.0 1.1e-36 126.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 EAQ83379.1 - 6.1e-10 39.0 0.1 2.4e-09 37.1 0.0 2.1 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain AAA_16 PF13191.6 EAQ83379.1 - 1.5e-05 25.5 0.2 0.0017 18.8 0.0 3.2 2 1 0 3 3 3 1 AAA ATPase domain AAA_lid_3 PF17862.1 EAQ83379.1 - 5.1e-05 23.0 0.0 0.00016 21.4 0.0 1.8 2 0 0 2 2 1 1 AAA+ lid domain RuvB_N PF05496.12 EAQ83379.1 - 7.6e-05 22.5 0.0 0.00016 21.5 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EAQ83379.1 - 0.00025 21.4 0.0 0.0057 16.9 0.0 2.6 2 1 1 3 3 2 1 AAA domain IstB_IS21 PF01695.17 EAQ83379.1 - 0.00095 18.9 0.0 0.0018 18.0 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.6 EAQ83379.1 - 0.0034 17.4 0.0 0.0063 16.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 EAQ83379.1 - 0.0036 17.0 0.0 0.0063 16.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 EAQ83379.1 - 0.0084 15.7 0.1 0.38 10.3 0.0 3.1 2 1 0 3 3 3 1 AAA domain TIP49 PF06068.13 EAQ83379.1 - 0.011 14.9 0.0 0.018 14.3 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_5 PF07728.14 EAQ83379.1 - 0.014 15.4 0.0 0.087 12.8 0.0 2.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 EAQ83379.1 - 0.024 15.2 0.0 0.056 14.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EAQ83379.1 - 0.025 15.0 0.0 0.053 13.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_17 PF13207.6 EAQ83379.1 - 0.027 14.9 0.0 0.061 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 EAQ83379.1 - 0.032 13.4 0.0 0.051 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Zeta_toxin PF06414.12 EAQ83379.1 - 0.034 13.4 0.9 0.05 12.9 0.0 1.7 2 0 0 2 2 1 0 Zeta toxin Torsin PF06309.11 EAQ83379.1 - 0.045 13.8 0.0 0.088 12.9 0.0 1.4 1 0 0 1 1 1 0 Torsin HET PF06985.11 EAQ83379.1 - 0.061 13.7 0.0 0.17 12.2 0.1 1.7 2 0 0 2 2 1 0 Heterokaryon incompatibility protein (HET) AAA_33 PF13671.6 EAQ83379.1 - 0.07 13.3 0.0 0.18 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 EAQ83379.1 - 0.11 11.8 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_2 PF07724.14 EAQ83379.1 - 0.12 12.4 0.0 0.31 11.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) Parvo_NS1 PF01057.17 EAQ83379.1 - 0.13 11.4 0.0 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NACHT PF05729.12 EAQ83379.1 - 0.18 11.7 0.0 1.6 8.6 0.0 2.2 1 1 1 2 2 2 0 NACHT domain PhoH PF02562.16 EAQ83379.1 - 0.25 10.7 0.0 0.45 9.9 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein zf-RVT PF13966.6 EAQ83381.1 - 0.019 15.6 0.0 0.16 12.7 0.0 2.3 2 0 0 2 2 2 0 zinc-binding in reverse transcriptase DUF4131 PF13567.6 EAQ83381.1 - 0.2 11.3 2.8 29 4.3 0.0 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4131) FAD_binding_3 PF01494.19 EAQ83382.1 - 4.1e-18 65.7 0.0 7.4e-18 64.9 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EAQ83382.1 - 4.3e-06 26.2 0.0 9.1e-06 25.1 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EAQ83382.1 - 0.00032 21.2 0.0 0.0028 18.2 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EAQ83382.1 - 0.0015 18.2 0.0 0.0045 16.6 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase SE PF08491.10 EAQ83382.1 - 0.0019 17.3 0.0 0.0036 16.4 0.0 1.4 1 0 0 1 1 1 1 Squalene epoxidase NAD_binding_8 PF13450.6 EAQ83382.1 - 0.0019 18.4 0.1 0.0045 17.2 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EAQ83382.1 - 0.003 16.3 0.0 0.0048 15.7 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein AlaDh_PNT_C PF01262.21 EAQ83382.1 - 0.003 16.9 0.0 0.0053 16.1 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 EAQ83382.1 - 0.0088 15.2 0.0 0.013 14.6 0.0 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 EAQ83382.1 - 0.014 14.8 0.1 0.026 13.9 0.1 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase 3HCDH_N PF02737.18 EAQ83382.1 - 0.15 11.9 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Peptidase_M24 PF00557.24 EAQ83383.1 - 1.8e-48 165.0 0.1 2.2e-48 164.7 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 EAQ83383.1 - 8.4e-20 70.8 9.3 2e-19 69.6 9.3 1.7 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 EAQ83383.1 - 3.5e-05 23.8 6.3 0.00011 22.2 6.3 1.9 1 0 0 1 1 1 1 MYND finger Cornichon PF03311.14 EAQ83384.1 - 1.9e-30 105.7 7.9 2.9e-30 105.1 7.9 1.2 1 0 0 1 1 1 1 Cornichon protein WD40 PF00400.32 EAQ83384.1 - 8e-29 99.3 9.1 8.4e-08 32.8 0.0 6.3 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAQ83384.1 - 1.6e-12 47.5 0.0 0.00034 20.9 0.0 4.9 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 EAQ83384.1 - 0.00057 19.5 0.0 0.0018 17.9 0.0 1.8 1 1 1 2 2 2 1 PQQ-like domain ADH_N PF08240.12 EAQ83385.1 - 0.00015 21.6 0.0 0.00036 20.4 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EAQ83385.1 - 0.0033 17.4 0.4 0.0065 16.4 0.4 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Amidoligase_2 PF12224.8 EAQ83387.1 - 3.8e-05 23.5 0.0 8.8e-05 22.3 0.0 1.6 2 0 0 2 2 2 1 Putative amidoligase enzyme zf-RVT PF13966.6 EAQ83387.1 - 0.061 14.0 0.0 0.13 12.9 0.0 1.5 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase DUF1748 PF08520.10 EAQ83388.1 - 5.4e-15 55.0 0.2 5.8e-15 54.9 0.2 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) PK PF00224.21 EAQ83389.1 - 1.7e-121 405.4 0.7 2.4e-121 404.9 0.7 1.2 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 EAQ83389.1 - 6.2e-36 123.2 0.0 1.2e-35 122.2 0.0 1.5 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 EAQ83389.1 - 0.00064 18.9 0.7 0.0021 17.3 0.3 1.9 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family Dynamin_N PF00350.23 EAQ83390.1 - 1.7e-21 77.0 0.0 3.4e-21 76.0 0.0 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 EAQ83390.1 - 7.7e-14 51.6 0.0 5.6e-12 45.5 0.0 2.4 2 0 0 2 2 2 2 Dynamin central region NAD_binding_10 PF13460.6 EAQ83392.1 - 3.6e-22 79.2 0.3 2.6e-21 76.3 0.3 2.0 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EAQ83392.1 - 0.012 15.0 0.1 0.055 12.9 0.0 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family PWWP PF00855.17 EAQ83393.1 - 0.14 12.6 0.1 0.36 11.3 0.1 1.7 1 1 1 2 2 2 0 PWWP domain Fungal_trans PF04082.18 EAQ83394.1 - 4.3e-15 55.5 0.0 7.8e-15 54.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EAQ83394.1 - 0.0001 22.3 8.3 0.0002 21.4 8.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ndc1_Nup PF09531.10 EAQ83395.1 - 0.51 9.0 2.7 0.55 8.8 2.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SOG2 PF10428.9 EAQ83395.1 - 1.3 8.1 7.7 1.5 7.9 7.7 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein CHORD PF04968.12 EAQ83398.1 - 0.022 15.5 0.8 0.055 14.2 0.8 1.6 1 0 0 1 1 1 0 CHORD TMEM214 PF10151.9 EAQ83398.1 - 1.4 7.3 5.1 2.4 6.5 5.1 1.3 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator MFS_1 PF07690.16 EAQ83399.1 - 1e-08 34.5 11.5 1e-08 34.5 11.5 1.9 1 1 0 2 2 2 1 Major Facilitator Superfamily zf-RVT PF13966.6 EAQ83400.1 - 0.16 12.7 0.0 0.38 11.5 0.0 1.7 2 0 0 2 2 2 0 zinc-binding in reverse transcriptase Glyco_hydro_61 PF03443.14 EAQ83401.1 - 3.5e-58 196.9 0.1 4.4e-58 196.6 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Pkinase PF00069.25 EAQ83402.1 - 1e-44 152.9 0.0 4.7e-44 150.7 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ83402.1 - 3.1e-31 108.6 0.0 4.5e-31 108.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EAQ83402.1 - 0.00086 18.7 0.0 0.002 17.5 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EAQ83402.1 - 0.0092 15.3 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EAQ83402.1 - 0.032 14.1 1.7 0.11 12.4 0.1 2.6 3 1 1 4 4 4 0 Phosphotransferase enzyme family CxC4 PF18717.1 EAQ83402.1 - 0.37 10.6 2.9 0.81 9.5 2.9 1.5 1 0 0 1 1 1 0 CxC4 like cysteine cluster associated with KDZ transposases Spt5-NGN PF03439.13 EAQ83405.1 - 1.3e-24 85.9 0.0 2.2e-24 85.2 0.0 1.4 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.8 EAQ83405.1 - 3.1e-20 73.0 10.4 3.1e-20 73.0 10.4 3.5 2 1 1 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal CTD PF12815.7 EAQ83405.1 - 3.7e-09 37.0 7.0 3.7e-09 37.0 7.0 3.9 1 1 1 2 2 2 1 Spt5 C-terminal nonapeptide repeat binding Spt4 KOW PF00467.29 EAQ83405.1 - 0.0017 18.2 1.0 0.0017 18.2 1.0 5.1 5 1 1 6 6 6 1 KOW motif DUF3912 PF13051.6 EAQ83405.1 - 0.0091 16.2 0.5 0.045 14.0 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3912) Cornifin PF02389.15 EAQ83405.1 - 1.1 9.5 4.2 2.2 8.5 4.2 1.4 1 0 0 1 1 1 0 Cornifin (SPRR) family Amidoligase_2 PF12224.8 EAQ83406.1 - 1.9e-07 31.0 0.0 1.4e-06 28.1 0.0 2.3 1 1 1 2 2 2 1 Putative amidoligase enzyme Mit_ribos_Mrp51 PF11709.8 EAQ83406.1 - 0.032 13.8 0.5 0.054 13.1 0.5 1.5 1 1 0 1 1 1 0 Mitochondrial ribosomal protein subunit Stm1_N PF09598.10 EAQ83406.1 - 1.4 9.9 5.8 2.9 8.8 5.8 1.5 1 0 0 1 1 1 0 Stm1 NUDE_C PF04880.13 EAQ83407.1 - 0.014 15.8 0.8 0.014 15.8 0.8 3.4 3 2 1 4 4 4 0 NUDE protein, C-terminal conserved region Abhydrolase_6 PF12697.7 EAQ83408.1 - 9.9e-11 42.7 6.5 1.5e-10 42.1 6.5 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EAQ83408.1 - 6e-07 29.0 0.2 8.5e-07 28.5 0.2 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EAQ83408.1 - 1.9e-05 24.4 0.1 2.8e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 EAQ83408.1 - 0.002 18.0 0.3 0.0031 17.4 0.3 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Lipase_3 PF01764.25 EAQ83408.1 - 0.028 14.3 0.2 0.048 13.5 0.2 1.3 1 0 0 1 1 1 0 Lipase (class 3) DLH PF01738.18 EAQ83408.1 - 0.089 12.3 0.0 0.33 10.5 0.0 1.8 2 0 0 2 2 2 0 Dienelactone hydrolase family HalOD1 PF18545.1 EAQ83409.1 - 0.15 12.4 1.2 5.7 7.3 0.0 2.8 3 0 0 3 3 3 0 Halobacterial output domain 1 NMT_C PF02799.15 EAQ83410.1 - 1.3e-86 289.5 0.0 2e-86 288.9 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 EAQ83410.1 - 6.8e-67 224.3 0.0 1.3e-66 223.4 0.0 1.4 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_9 PF13527.7 EAQ83410.1 - 7.7e-06 26.0 0.0 8.5e-05 22.6 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Ribosomal_S25 PF03297.15 EAQ83410.1 - 0.016 15.4 1.2 0.041 14.1 0.7 1.9 2 0 0 2 2 2 0 S25 ribosomal protein Drc1-Sld2 PF11719.8 EAQ83410.1 - 0.11 12.0 4.3 0.15 11.6 4.3 1.2 1 0 0 1 1 1 0 DNA replication and checkpoint protein Abhydrolase_1 PF00561.20 EAQ83411.1 - 0.065 12.9 0.0 0.084 12.5 0.0 1.1 1 0 0 1 1 1 0 alpha/beta hydrolase fold Tannase PF07519.11 EAQ83412.1 - 3.8e-76 256.9 1.1 4.2e-62 210.6 0.2 2.0 1 1 1 2 2 2 2 Tannase and feruloyl esterase Abhydrolase_1 PF00561.20 EAQ83412.1 - 0.0081 15.8 0.1 0.015 14.9 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold zf-RVT PF13966.6 EAQ83413.1 - 0.084 13.6 0.0 0.22 12.2 0.0 1.6 2 0 0 2 2 2 0 zinc-binding in reverse transcriptase adh_short PF00106.25 EAQ83414.1 - 6.2e-30 104.1 0.0 2.3e-16 59.9 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EAQ83414.1 - 1.4e-21 77.2 0.1 2.8e-12 46.7 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 EAQ83414.1 - 7.6e-06 25.9 0.0 1.3e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EAQ83414.1 - 0.0001 22.0 0.0 0.00016 21.3 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family NAD_binding_2 PF03446.15 EAQ83414.1 - 0.00052 20.2 0.0 0.001 19.3 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.16 EAQ83414.1 - 0.011 15.3 0.0 0.019 14.6 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DUF1776 PF08643.10 EAQ83414.1 - 0.012 15.0 0.0 0.035 13.5 0.0 1.6 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) DFP PF04127.15 EAQ83414.1 - 0.019 14.8 0.1 0.032 14.0 0.1 1.2 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Epimerase PF01370.21 EAQ83414.1 - 0.021 14.3 0.0 0.036 13.5 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Rossmann-like PF10727.9 EAQ83414.1 - 0.036 13.9 0.3 0.13 12.1 0.3 2.1 1 1 0 1 1 1 0 Rossmann-like domain TrkA_N PF02254.18 EAQ83414.1 - 0.048 13.9 0.0 0.086 13.1 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain KR PF08659.10 EAQ83414.1 - 0.073 13.0 0.0 0.35 10.8 0.0 1.9 2 0 0 2 2 2 0 KR domain FtsJ PF01728.19 EAQ83414.1 - 0.21 11.7 0.0 0.3 11.2 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase Glyco_hydro_114 PF03537.13 EAQ83415.1 - 3.1e-48 164.1 0.4 3.8e-48 163.8 0.4 1.0 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 Polysacc_synt_4 PF04669.13 EAQ83417.1 - 7.9e-24 84.3 1.2 3.2e-22 79.0 1.2 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis ABC_membrane PF00664.23 EAQ83418.1 - 2.2e-41 142.4 9.4 2.9e-17 63.2 0.1 3.1 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.27 EAQ83418.1 - 5.9e-26 91.6 0.0 5e-15 56.2 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_16 PF13191.6 EAQ83418.1 - 2.7e-06 27.9 0.4 0.071 13.5 0.0 3.1 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 EAQ83418.1 - 3.1e-06 27.5 0.0 0.039 14.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 EAQ83418.1 - 6.7e-06 25.8 3.6 0.014 15.1 1.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.6 EAQ83418.1 - 1.2e-05 25.0 0.1 0.11 12.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 EAQ83418.1 - 1.3e-05 25.1 0.0 0.069 13.1 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 EAQ83418.1 - 0.00022 21.8 0.2 0.21 12.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EAQ83418.1 - 0.00023 21.4 0.1 0.34 11.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.6 EAQ83418.1 - 0.0003 20.7 0.0 0.61 9.8 0.1 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 EAQ83418.1 - 0.00038 21.0 0.1 1.6 9.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 EAQ83418.1 - 0.00077 19.3 0.1 0.3 10.7 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 EAQ83418.1 - 0.0013 18.8 0.4 1.7 8.7 0.0 3.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.12 EAQ83418.1 - 0.0031 16.8 0.0 1.2 8.4 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin AAA_30 PF13604.6 EAQ83418.1 - 0.0052 16.5 0.1 3.2 7.4 0.0 3.0 3 0 0 3 3 3 1 AAA domain APS_kinase PF01583.20 EAQ83418.1 - 0.0056 16.6 0.9 5.6 6.8 0.0 3.2 3 0 0 3 3 3 0 Adenylylsulphate kinase SMC_N PF02463.19 EAQ83418.1 - 0.011 15.2 0.4 9.7 5.5 0.1 3.2 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 EAQ83418.1 - 0.021 14.9 0.0 2.3 8.3 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase PEPCK_ATP PF01293.20 EAQ83418.1 - 0.022 13.5 0.7 0.21 10.2 0.0 2.5 3 0 0 3 3 3 0 Phosphoenolpyruvate carboxykinase NB-ARC PF00931.22 EAQ83418.1 - 0.025 13.8 0.1 1.6 7.9 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain DUF87 PF01935.17 EAQ83418.1 - 0.028 14.5 1.3 3.2 7.8 0.1 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_24 PF13479.6 EAQ83418.1 - 0.035 13.8 0.2 2.4 7.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EAQ83418.1 - 0.038 13.5 0.1 3.9 6.9 0.0 2.7 3 0 0 3 3 2 0 P-loop containing dynein motor region RNA_helicase PF00910.22 EAQ83418.1 - 0.044 14.2 0.1 8.9 6.8 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_28 PF13521.6 EAQ83418.1 - 0.044 14.0 2.1 0.79 10.0 0.3 2.7 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 EAQ83418.1 - 0.046 13.1 0.0 12 5.2 0.0 2.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI PRK PF00485.18 EAQ83418.1 - 0.1 12.3 0.1 3.8 7.2 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family NACHT PF05729.12 EAQ83418.1 - 0.12 12.3 1.2 9 6.2 0.1 2.4 2 0 0 2 2 2 0 NACHT domain Ploopntkinase3 PF18751.1 EAQ83418.1 - 0.14 12.1 0.1 1.3 8.9 0.0 2.4 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 ATP-synt_ab PF00006.25 EAQ83418.1 - 0.14 11.8 0.1 1.3 8.7 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain MobB PF03205.14 EAQ83418.1 - 0.19 11.6 0.2 7.1 6.5 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ATPase PF06745.13 EAQ83418.1 - 0.21 10.9 3.3 12 5.2 0.1 3.4 4 0 0 4 4 4 0 KaiC PhoH PF02562.16 EAQ83418.1 - 0.28 10.6 1.0 12 5.3 0.1 2.4 2 0 0 2 2 2 0 PhoH-like protein DUF463 PF04317.12 EAQ83419.1 - 0.0089 15.0 0.0 0.012 14.6 0.0 1.1 1 0 0 1 1 1 1 YcjX-like family, DUF463 MFS_1 PF07690.16 EAQ83420.1 - 1.4e-28 99.9 34.9 5.1e-27 94.7 17.4 2.5 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EAQ83420.1 - 1.9e-12 46.4 3.2 3.1e-12 45.7 3.2 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) VIT1 PF01988.19 EAQ83420.1 - 0.039 13.8 0.0 0.039 13.8 0.0 3.8 3 2 1 4 4 4 0 VIT family Tim54 PF11711.8 EAQ83420.1 - 0.15 10.8 1.8 0.24 10.1 1.8 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF3438 PF11920.8 EAQ83420.1 - 0.32 10.2 0.6 0.51 9.6 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3438) BT1 PF03092.16 EAQ83420.1 - 0.48 8.6 5.7 1 7.5 0.4 2.6 3 0 0 3 3 3 0 BT1 family DUF3784 PF12650.7 EAQ83420.1 - 1 9.6 0.0 1 9.6 0.0 5.0 4 1 1 5 5 5 0 Domain of unknown function (DUF3784) NST1 PF13945.6 EAQ83420.1 - 1.3 9.1 10.1 2.2 8.3 10.1 1.3 1 0 0 1 1 1 0 Salt tolerance down-regulator DUF805 PF05656.14 EAQ83420.1 - 1.6 9.2 14.9 0.065 13.7 3.3 3.3 3 2 0 3 3 3 0 Protein of unknown function (DUF805) DUF1769 PF08588.10 EAQ83421.1 - 1.1e-27 96.0 0.6 2.1e-27 95.0 0.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) MCLC PF05934.11 EAQ83421.1 - 0.057 12.2 0.4 0.085 11.6 0.4 1.1 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) PC_rep PF01851.22 EAQ83422.1 - 1.2e-38 129.6 19.0 2e-09 37.4 0.0 8.3 7 0 0 7 7 7 7 Proteasome/cyclosome repeat RPN2_C PF18004.1 EAQ83422.1 - 6.3e-33 114.0 4.4 6.3e-33 114.0 4.4 2.8 3 1 0 3 3 3 1 26S proteasome regulatory subunit RPN2 C-terminal domain HEAT_2 PF13646.6 EAQ83422.1 - 3.5e-22 78.6 1.2 3.9e-14 52.8 0.0 6.2 5 1 1 6 6 6 3 HEAT repeats HEAT_EZ PF13513.6 EAQ83422.1 - 1.2e-06 28.8 2.3 0.00057 20.3 0.0 5.3 5 1 1 6 6 6 2 HEAT-like repeat HEAT PF02985.22 EAQ83422.1 - 2.5e-06 27.3 0.1 1.4 9.4 0.0 5.9 5 0 0 5 5 5 1 HEAT repeat Cnd1 PF12717.7 EAQ83422.1 - 0.038 14.0 2.0 3.3 7.7 0.0 3.6 3 1 1 4 4 4 0 non-SMC mitotic condensation complex subunit 1 ANAPC3 PF12895.7 EAQ83422.1 - 0.096 12.9 0.4 1.9 8.8 0.1 2.8 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 mRNA_triPase PF02940.15 EAQ83423.1 - 2.5e-58 197.4 0.0 3.7e-58 196.8 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain NmrA PF05368.13 EAQ83424.1 - 4.9e-23 81.9 0.6 4.5e-22 78.7 0.6 2.0 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EAQ83424.1 - 4.2e-16 59.4 1.2 4.2e-16 59.4 1.2 1.7 2 1 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 EAQ83424.1 - 2.8e-07 30.2 0.1 4.3e-07 29.7 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EAQ83424.1 - 0.0016 17.6 0.2 0.0026 16.9 0.2 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Semialdhyde_dh PF01118.24 EAQ83424.1 - 0.01 16.3 0.1 0.024 15.0 0.1 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 EAQ83424.1 - 0.032 14.3 0.0 0.059 13.4 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 EAQ83424.1 - 0.032 14.8 0.0 0.16 12.6 0.0 2.2 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_8 PF13450.6 EAQ83425.1 - 2e-11 44.0 0.0 6.3e-11 42.3 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 EAQ83425.1 - 2.4e-09 37.1 1.5 4.6e-09 36.1 1.5 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 EAQ83425.1 - 2e-08 34.0 0.0 8.1e-07 28.7 0.0 2.4 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 EAQ83425.1 - 1.6e-06 27.5 0.8 2.4e-06 26.9 0.8 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 EAQ83425.1 - 9.8e-06 24.5 0.3 1.4e-05 24.0 0.3 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 EAQ83425.1 - 7.2e-05 23.3 0.4 0.00014 22.3 0.4 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EAQ83425.1 - 9.6e-05 21.7 0.2 0.00015 21.1 0.2 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EAQ83425.1 - 0.00018 20.9 0.3 0.00027 20.3 0.3 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EAQ83425.1 - 0.00022 20.9 0.9 0.00022 20.9 0.9 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EAQ83425.1 - 0.00049 19.4 0.6 0.00094 18.5 0.6 1.5 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 EAQ83425.1 - 0.0018 17.6 0.3 0.0029 16.9 0.3 1.2 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 EAQ83425.1 - 0.0022 17.1 0.5 0.0036 16.4 0.5 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A IlvN PF07991.12 EAQ83425.1 - 0.39 10.3 1.7 0.53 9.8 0.4 1.8 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain FAD_binding_4 PF01565.23 EAQ83426.1 - 3.6e-19 68.9 0.2 8.9e-19 67.6 0.2 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EAQ83426.1 - 0.11 12.7 0.1 0.28 11.3 0.1 1.7 1 0 0 1 1 1 0 Berberine and berberine like p450 PF00067.22 EAQ83428.1 - 2.4e-34 118.9 0.0 7.3e-22 77.7 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 MFS_1 PF07690.16 EAQ83429.1 - 1.6e-39 135.9 60.1 1.6e-39 135.9 60.1 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EAQ83429.1 - 1.8e-12 46.5 16.5 3e-12 45.8 16.5 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EAQ83429.1 - 1.6e-09 37.1 11.4 1.6e-09 37.1 11.4 2.9 2 1 0 3 3 3 1 Sugar (and other) transporter p450 PF00067.22 EAQ83430.1 - 5.1e-10 38.7 0.2 1.3e-09 37.4 0.0 1.7 2 0 0 2 2 2 1 Cytochrome P450 Dimer_Tnp_hAT PF05699.14 EAQ83431.1 - 2.9e-13 49.4 0.2 6.8e-13 48.2 0.2 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF659 PF04937.15 EAQ83431.1 - 0.062 13.2 0.0 0.28 11.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF 659) HRXXH PF13933.6 EAQ83432.1 - 1.6e-105 352.1 0.0 1.9e-105 351.8 0.0 1.0 1 0 0 1 1 1 1 Putative peptidase family Aspzincin_M35 PF14521.6 EAQ83432.1 - 5.4e-07 30.3 0.0 1e-06 29.4 0.0 1.4 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase Peptidase_M35 PF02102.15 EAQ83432.1 - 0.00013 20.9 1.3 0.00036 19.5 0.0 2.2 2 1 0 2 2 2 1 Deuterolysin metalloprotease (M35) family DBD_HTH PF18430.1 EAQ83432.1 - 0.12 12.1 0.6 0.23 11.3 0.6 1.4 1 0 0 1 1 1 0 Putative DNA-binding domain Mannosyl_trans3 PF11051.8 EAQ83433.1 - 0.0058 16.0 0.0 0.0085 15.5 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative SMODS PF18144.1 EAQ83434.1 - 0.059 13.5 0.0 0.059 13.5 0.0 1.0 1 0 0 1 1 1 0 Second Messenger Oligonucleotide or Dinucleotide Synthetase domain Glyco_hydro_62 PF03664.13 EAQ83435.1 - 9.7e-148 490.8 9.4 1.1e-147 490.6 9.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 TSR PF18487.1 EAQ83436.1 - 0.059 13.6 0.0 0.085 13.1 0.0 1.3 1 0 0 1 1 1 0 Thrombospondin type 1 repeat zf-C2H2_4 PF13894.6 EAQ83437.1 - 1.1e-07 32.1 3.2 0.0036 18.0 0.1 2.8 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 EAQ83437.1 - 8.5e-07 29.1 3.1 0.0043 17.4 0.1 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 EAQ83437.1 - 0.035 14.1 1.7 0.4 10.7 0.5 2.4 1 1 1 2 2 2 0 C2H2-type zinc finger Thioredoxin_2 PF13098.6 EAQ83437.1 - 0.16 12.5 2.5 1.2 9.6 0.1 2.2 1 1 0 2 2 2 0 Thioredoxin-like domain zf-Di19 PF05605.12 EAQ83437.1 - 0.17 12.2 1.3 6.2 7.2 0.8 2.3 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Glyco_hydro_115 PF15979.5 EAQ83438.1 - 2e-97 326.7 2.3 3.4e-76 256.9 0.1 2.6 2 1 1 3 3 3 2 Glycosyl hydrolase family 115 GH115_C PF17829.1 EAQ83438.1 - 2.7e-44 151.0 0.0 5.2e-44 150.1 0.0 1.5 1 0 0 1 1 1 1 Gylcosyl hydrolase family 115 C-terminal domain DUF4360 PF14273.6 EAQ83439.1 - 5e-15 55.8 0.3 6.2e-15 55.5 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DUF5619 PF18505.1 EAQ83439.1 - 0.11 12.5 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5619) Kinesin PF00225.23 EAQ83440.1 - 4.4e-115 384.2 0.0 6.5e-115 383.6 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EAQ83440.1 - 1e-26 93.7 0.0 2.1e-26 92.6 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding Herpes_UL14 PF03580.14 EAQ83440.1 - 0.0042 17.3 1.5 0.0089 16.3 1.5 1.5 1 0 0 1 1 1 1 Herpesvirus UL14-like protein AAA_33 PF13671.6 EAQ83440.1 - 0.11 12.7 0.3 0.38 10.9 0.0 2.1 2 1 0 2 2 2 0 AAA domain MAGI_u1 PF16663.5 EAQ83440.1 - 0.15 12.1 1.3 1.9 8.6 0.1 3.1 2 0 0 2 2 2 0 Unstructured region on MAGI Sugar_tr PF00083.24 EAQ83441.1 - 2.6e-115 385.9 21.3 5.5e-115 384.8 21.3 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EAQ83441.1 - 1e-25 90.4 54.3 2.6e-22 79.2 29.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Myb_DNA-bind_6 PF13921.6 EAQ83443.1 - 4.9e-06 26.7 1.7 6.7e-05 23.1 1.7 2.4 1 1 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EAQ83443.1 - 8.8e-06 25.8 1.7 2.4e-05 24.4 0.3 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain Rap1_C PF11626.8 EAQ83443.1 - 0.012 15.7 0.0 0.026 14.6 0.0 1.6 1 0 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain MSP1_C PF07462.11 EAQ83443.1 - 0.13 11.0 0.0 0.63 8.7 0.0 1.8 2 0 0 2 2 2 0 Merozoite surface protein 1 (MSP1) C-terminus G_path_suppress PF15991.5 EAQ83443.1 - 0.25 11.4 2.5 0.34 11.0 2.5 1.2 1 0 0 1 1 1 0 G-protein pathway suppressor UbiA PF01040.18 EAQ83444.1 - 1.3e-59 201.5 20.7 1.3e-59 201.5 20.7 1.7 1 1 1 2 2 2 1 UbiA prenyltransferase family PBP1_TM PF14812.6 EAQ83444.1 - 0.16 12.4 1.5 0.35 11.3 1.5 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.10 EAQ83444.1 - 1 9.8 9.9 1.9 8.9 9.9 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Helo_like_N PF17111.5 EAQ83445.1 - 6.5e-07 28.9 0.2 1.3e-06 27.9 0.2 1.5 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins RdRP_3 PF00998.23 EAQ83446.1 - 0.21 10.3 0.8 0.34 9.6 0.8 1.2 1 0 0 1 1 1 0 Viral RNA dependent RNA polymerase Mo-co_dimer PF03404.16 EAQ83447.1 - 1.6e-26 92.9 0.0 3.4e-16 59.5 0.0 3.1 3 0 0 3 3 3 2 Mo-co oxidoreductase dimerisation domain Cyt-b5 PF00173.28 EAQ83447.1 - 1.8e-11 44.0 0.0 3.3e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain BNR PF02012.20 EAQ83447.1 - 0.46 10.7 4.5 0.85 9.9 0.3 2.9 2 0 0 2 2 2 0 BNR/Asp-box repeat Stm1_N PF09598.10 EAQ83447.1 - 0.83 10.5 12.6 12 6.8 0.0 3.8 3 0 0 3 3 3 0 Stm1 DUF3506 PF12014.8 EAQ83448.1 - 1.2e-51 174.4 0.0 1.4e-51 174.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3506) Cwf_Cwc_15 PF04889.12 EAQ83448.1 - 0.048 13.4 2.8 0.059 13.1 2.8 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DNA_pol_phi PF04931.13 EAQ83448.1 - 2 6.4 5.5 2.6 6.0 5.5 1.0 1 0 0 1 1 1 0 DNA polymerase phi Cupin_2 PF07883.11 EAQ83450.1 - 1.2e-07 31.3 0.6 2.3e-07 30.4 0.6 1.6 1 1 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 EAQ83450.1 - 0.018 14.7 0.0 0.028 14.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF861) AraC_binding PF02311.19 EAQ83450.1 - 0.052 13.5 0.1 0.071 13.0 0.1 1.3 1 1 0 1 1 1 0 AraC-like ligand binding domain Sugarporin_N PF11471.8 EAQ83451.1 - 0.0053 16.7 2.0 0.017 15.1 2.0 1.9 1 0 0 1 1 1 1 Maltoporin periplasmic N-terminal extension Pox_A_type_inc PF04508.12 EAQ83451.1 - 0.035 13.9 0.0 0.1 12.5 0.0 1.8 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat Arteri_nucleo PF01481.16 EAQ83451.1 - 0.041 14.2 1.4 0.088 13.1 1.4 1.5 1 0 0 1 1 1 0 Arterivirus nucleocapsid protein GIT_CC PF16559.5 EAQ83451.1 - 0.78 9.7 5.7 0.61 10.0 0.1 3.0 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor TMEM214 PF10151.9 EAQ83451.1 - 1.4 7.3 2.9 2.2 6.6 2.9 1.2 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator DUF3292 PF11696.8 EAQ83451.1 - 5.4 5.3 9.5 6.7 5.0 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3292) MIP-T3_C PF17749.1 EAQ83451.1 - 6.6 6.7 8.3 0.31 11.0 0.6 2.2 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region HIP1_clath_bdg PF16515.5 EAQ83453.1 - 0.0018 18.9 28.8 0.015 15.8 8.0 4.7 4 2 1 5 5 5 2 Clathrin-binding domain of Huntingtin-interacting protein 1 ERM PF00769.19 EAQ83453.1 - 0.0057 16.5 23.6 0.68 9.7 6.2 3.3 3 0 0 3 3 3 2 Ezrin/radixin/moesin family Phage_GP20 PF06810.11 EAQ83453.1 - 0.012 15.4 9.3 0.6 9.9 2.5 2.8 2 0 0 2 2 2 0 Phage minor structural protein GP20 DUF641 PF04859.12 EAQ83453.1 - 0.014 15.8 13.6 0.14 12.5 1.2 4.1 3 1 1 4 4 4 0 Plant protein of unknown function (DUF641) YkyA PF10368.9 EAQ83453.1 - 0.017 14.8 2.7 0.017 14.8 2.7 1.9 2 0 0 2 2 2 0 Putative cell-wall binding lipoprotein Spc42p PF11544.8 EAQ83453.1 - 0.077 13.0 1.6 18 5.4 0.5 3.3 3 0 0 3 3 3 0 Spindle pole body component Spc42p Fez1 PF06818.15 EAQ83453.1 - 0.09 13.2 17.3 0.92 9.9 1.7 2.9 2 1 0 2 2 2 0 Fez1 FAM76 PF16046.5 EAQ83453.1 - 0.25 10.6 2.0 0.58 9.5 0.1 2.3 2 0 0 2 2 2 0 FAM76 protein Muted PF14942.6 EAQ83453.1 - 0.29 11.5 9.8 1.9 8.8 0.1 2.8 3 0 0 3 3 3 0 Organelle biogenesis, Muted-like protein DUF724 PF05266.14 EAQ83453.1 - 0.32 10.8 6.6 2.1 8.1 1.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF724) HAP1_N PF04849.13 EAQ83453.1 - 0.41 9.8 21.2 0.25 10.5 2.6 2.9 3 0 0 3 3 3 0 HAP1 N-terminal conserved region HOOK PF05622.12 EAQ83453.1 - 0.42 8.7 16.9 0.2 9.8 1.7 2.4 3 0 0 3 3 3 0 HOOK protein HsbA PF12296.8 EAQ83453.1 - 0.5 10.8 7.9 1.3 9.4 5.3 2.6 2 1 0 2 2 2 0 Hydrophobic surface binding protein A Spc7 PF08317.11 EAQ83453.1 - 0.54 9.1 21.2 0.43 9.4 3.3 3.1 4 0 0 4 4 4 0 Spc7 kinetochore protein Amidinotransf PF02274.17 EAQ83453.1 - 1.4 7.9 4.2 0.21 10.6 0.3 1.5 2 0 0 2 2 2 0 Amidinotransferase RF-1 PF00472.20 EAQ83453.1 - 1.6 8.7 7.5 0.61 10.0 0.3 2.5 2 0 0 2 2 2 0 RF-1 domain OmpH PF03938.14 EAQ83453.1 - 1.6 9.1 13.8 3.1 8.1 2.3 2.8 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) GAS PF13851.6 EAQ83453.1 - 1.8 7.9 20.5 0.38 10.1 4.1 3.6 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding DUF4200 PF13863.6 EAQ83453.1 - 3 8.2 20.5 2 8.8 6.3 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4200) Seryl_tRNA_N PF02403.22 EAQ83453.1 - 5.6 7.2 17.0 0.12 12.6 3.8 3.6 4 1 0 4 4 3 0 Seryl-tRNA synthetase N-terminal domain APG6_N PF17675.1 EAQ83453.1 - 6.8 7.2 29.2 1.9 9.0 5.7 3.7 4 0 0 4 4 3 0 Apg6 coiled-coil region PRKG1_interact PF15898.5 EAQ83453.1 - 7.9 7.4 20.5 8 7.4 2.0 4.0 4 0 0 4 4 3 0 cGMP-dependent protein kinase interacting domain Spore_YunB PF09560.10 EAQ83454.1 - 0.083 12.9 0.0 0.096 12.7 0.0 1.1 1 0 0 1 1 1 0 Sporulation protein YunB (Spo_YunB) DEAD PF00270.29 EAQ83457.1 - 1.1e-42 145.8 0.0 1.5e-42 145.3 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EAQ83457.1 - 8.6e-28 96.9 0.5 6.8e-27 94.0 0.3 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EAQ83457.1 - 0.0014 18.7 0.0 0.0023 17.9 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 EAQ83457.1 - 0.11 11.8 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit SecE PF00584.20 EAQ83459.1 - 0.089 12.7 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 SecE/Sec61-gamma subunits of protein translocation complex Gly_transf_sug PF04488.15 EAQ83461.1 - 4.1e-07 30.5 0.0 5.4e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 EAQ83461.1 - 0.0039 16.6 0.0 0.0047 16.3 0.0 1.1 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein GRP PF07172.11 EAQ83462.1 - 9.3 7.0 19.4 20 6.0 19.4 1.5 1 1 0 1 1 1 0 Glycine rich protein family DUF1479 PF07350.12 EAQ83464.1 - 2.8e-158 527.0 0.0 3.3e-158 526.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) PhyH PF05721.13 EAQ83464.1 - 0.0059 16.9 0.1 1 9.6 0.0 2.5 2 1 0 2 2 2 2 Phytanoyl-CoA dioxygenase (PhyH) DUF1993 PF09351.10 EAQ83465.1 - 1.2e-51 175.0 0.0 1.4e-51 174.9 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) DUF2157 PF09925.9 EAQ83468.1 - 5.4 6.8 10.1 0.16 11.8 1.2 2.6 3 0 0 3 3 3 0 Predicted membrane protein (DUF2157) SelK_SelG PF10961.8 EAQ83470.1 - 0.11 13.1 0.2 2.3 8.9 0.0 2.5 2 0 0 2 2 2 0 Selenoprotein SelK_SelG p450 PF00067.22 EAQ83472.1 - 2e-28 99.4 0.0 2.1e-19 69.7 0.2 3.0 1 1 1 2 2 2 2 Cytochrome P450 DUF1996 PF09362.10 EAQ83473.1 - 4e-54 184.1 0.8 2.9e-26 92.9 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF1996) zf-C2H2_4 PF13894.6 EAQ83474.1 - 1.1e-05 25.8 17.1 0.19 12.7 1.1 5.5 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EAQ83474.1 - 0.045 14.0 0.9 0.045 14.0 0.9 3.7 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 EAQ83474.1 - 0.93 10.1 17.1 7.6 7.2 0.9 4.9 4 1 1 5 5 5 0 Zinc finger, C2H2 type DZR PF12773.7 EAQ83474.1 - 1.8 8.6 4.5 2.9 8.0 0.4 2.8 3 0 0 3 3 3 0 Double zinc ribbon zf_UBZ PF18439.1 EAQ83474.1 - 2.4 7.8 7.9 3.7 7.2 0.9 3.7 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger zf-met PF12874.7 EAQ83474.1 - 4.7 7.7 12.0 0.38 11.2 0.8 4.1 4 0 0 4 4 4 0 Zinc-finger of C2H2 type Nop PF01798.18 EAQ83475.1 - 2e-80 269.6 0.0 3.4e-80 268.8 0.0 1.4 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 EAQ83475.1 - 3.8e-16 59.2 0.0 3.8e-16 59.2 0.0 2.3 2 0 0 2 2 2 1 NOP5NT (NUC127) domain DUF3525 PF12039.8 EAQ83475.1 - 0.042 12.6 0.2 0.26 10.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3525) OHCU_decarbox PF09349.10 EAQ83475.1 - 0.051 14.1 0.1 0.13 12.8 0.1 1.6 1 0 0 1 1 1 0 OHCU decarboxylase Red1 PF07964.11 EAQ83475.1 - 0.08 11.2 12.5 0.11 10.8 12.5 1.2 1 0 0 1 1 1 0 Rec10 / Red1 DUF913 PF06025.12 EAQ83475.1 - 0.71 8.8 6.4 1.1 8.1 6.4 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) GAGA_bind PF06217.12 EAQ83475.1 - 1.2 9.4 9.3 1.9 8.7 9.3 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family ETRAMP PF09716.10 EAQ83475.1 - 6.5 6.9 8.6 2.7 8.1 2.6 2.9 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) RNA_polI_A34 PF08208.11 EAQ83475.1 - 7 6.7 23.7 11 6.1 23.7 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 AAA PF00004.29 EAQ83476.1 - 1.9e-42 144.8 0.0 3.6e-42 143.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 EAQ83476.1 - 2.4e-29 101.1 0.3 9.4e-29 99.2 0.3 2.1 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 EAQ83476.1 - 1.3e-22 79.6 3.0 4e-22 78.1 3.0 1.9 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain AAA_lid_3 PF17862.1 EAQ83476.1 - 5.7e-06 26.0 0.2 0.00029 20.6 0.0 3.3 4 0 0 4 4 3 1 AAA+ lid domain AAA_16 PF13191.6 EAQ83476.1 - 7.5e-06 26.4 0.2 0.00014 22.3 0.1 2.8 2 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 EAQ83476.1 - 1.5e-05 24.8 0.0 3e-05 23.8 0.0 1.6 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 EAQ83476.1 - 5.7e-05 23.1 0.0 0.00029 20.9 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 EAQ83476.1 - 6.5e-05 23.3 0.0 0.013 15.8 0.0 2.9 2 0 0 2 2 2 1 RNA helicase IstB_IS21 PF01695.17 EAQ83476.1 - 6.7e-05 22.7 0.0 0.00016 21.5 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.13 EAQ83476.1 - 0.00018 20.9 0.0 0.00042 19.6 0.0 1.6 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 EAQ83476.1 - 0.00018 21.8 0.2 0.023 15.0 0.0 2.6 1 1 1 2 2 2 1 AAA domain AAA_14 PF13173.6 EAQ83476.1 - 0.00033 20.7 0.0 0.00076 19.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 EAQ83476.1 - 0.00039 19.7 0.0 0.0014 17.8 0.0 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF815) AAA_33 PF13671.6 EAQ83476.1 - 0.00071 19.8 0.0 0.0024 18.0 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 EAQ83476.1 - 0.00076 19.1 0.7 0.54 9.8 0.1 3.2 1 1 2 3 3 3 1 AAA domain AAA_18 PF13238.6 EAQ83476.1 - 0.0013 19.3 0.0 0.0052 17.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.14 EAQ83476.1 - 0.0014 18.8 0.0 0.0054 16.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_24 PF13479.6 EAQ83476.1 - 0.0044 16.8 0.0 0.013 15.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 EAQ83476.1 - 0.012 16.1 0.0 0.085 13.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EAQ83476.1 - 0.014 15.0 0.0 0.097 12.2 0.0 2.4 2 1 0 2 2 2 0 P-loop containing dynein motor region NACHT PF05729.12 EAQ83476.1 - 0.021 14.8 0.0 0.39 10.6 0.0 2.5 2 1 1 3 3 2 0 NACHT domain Mg_chelatase PF01078.21 EAQ83476.1 - 0.031 13.7 0.0 0.085 12.2 0.0 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Torsin PF06309.11 EAQ83476.1 - 0.031 14.4 0.1 0.15 12.1 0.0 2.0 2 0 0 2 2 2 0 Torsin Parvo_NS1 PF01057.17 EAQ83476.1 - 0.054 12.6 0.0 0.094 11.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Zeta_toxin PF06414.12 EAQ83476.1 - 0.094 12.0 0.5 1.6 8.0 0.1 2.9 2 1 1 3 3 3 0 Zeta toxin ATPase_2 PF01637.18 EAQ83476.1 - 0.12 12.3 0.1 0.93 9.4 0.0 2.2 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 EAQ83476.1 - 0.12 12.0 0.0 0.37 10.5 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain CPT PF07931.12 EAQ83476.1 - 0.13 12.1 0.0 0.67 9.8 0.0 2.1 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein PhoH PF02562.16 EAQ83476.1 - 0.17 11.3 0.1 0.17 11.3 0.1 1.7 2 0 0 2 2 1 0 PhoH-like protein ABC_tran PF00005.27 EAQ83476.1 - 0.18 12.3 0.2 1.9 9.0 0.0 2.6 3 1 0 3 3 2 0 ABC transporter Prefoldin_2 PF01920.20 EAQ83477.1 - 2.7e-17 62.6 7.4 4e-17 62.1 7.4 1.2 1 0 0 1 1 1 1 Prefoldin subunit NPV_P10 PF05531.12 EAQ83477.1 - 0.14 12.6 1.7 0.28 11.7 1.7 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein betaPIX_CC PF16523.5 EAQ83477.1 - 0.22 11.4 2.9 0.7 9.8 2.9 1.8 1 0 0 1 1 1 0 betaPIX coiled coil OmpH PF03938.14 EAQ83477.1 - 0.68 10.3 7.5 0.99 9.7 7.5 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DivIC PF04977.15 EAQ83477.1 - 4.7 7.1 10.0 5.8 6.8 6.6 2.5 2 1 0 2 2 2 0 Septum formation initiator JAB PF01398.21 EAQ83478.1 - 1.8e-15 57.0 0.0 3e-15 56.2 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease USP8_dimer PF08969.11 EAQ83478.1 - 3.8e-06 27.1 0.0 7.1e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 USP8 dimerisation domain Prok-JAB PF14464.6 EAQ83478.1 - 0.00032 20.5 0.0 0.00078 19.2 0.0 1.6 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Beta-lactamase PF00144.24 EAQ83479.1 - 2.7e-16 59.8 1.6 5.5e-08 32.4 0.0 2.2 1 1 0 2 2 2 2 Beta-lactamase HET PF06985.11 EAQ83480.1 - 3.3e-10 40.5 0.7 3.3e-10 40.5 0.7 2.5 3 0 0 3 3 3 1 Heterokaryon incompatibility protein (HET) ApoO PF09769.9 EAQ83480.1 - 0.023 14.7 0.0 0.064 13.2 0.0 1.7 1 0 0 1 1 1 0 Apolipoprotein O GMC_oxred_N PF00732.19 EAQ83481.1 - 1.9e-44 152.2 1.9 3e-44 151.6 1.9 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EAQ83481.1 - 1.1e-29 103.8 0.1 1.1e-28 100.6 0.0 2.2 2 0 0 2 2 2 1 GMC oxidoreductase DAO PF01266.24 EAQ83481.1 - 0.0017 18.0 0.3 0.018 14.7 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EAQ83481.1 - 0.072 13.3 0.1 0.18 12.1 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EAQ83481.1 - 0.74 9.0 3.6 3.7 6.7 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_4 PF01565.23 EAQ83482.1 - 2.8e-24 85.4 1.4 5.2e-24 84.6 1.4 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EAQ83482.1 - 5.1e-10 39.3 0.0 1.1e-09 38.2 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like Abhydrolase_3 PF07859.13 EAQ83482.1 - 0.00089 19.2 8.2 0.33 10.8 3.0 3.5 2 1 1 3 3 3 2 alpha/beta hydrolase fold adh_short PF00106.25 EAQ83483.1 - 2.7e-38 131.4 0.0 3.6e-38 131.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EAQ83483.1 - 7.8e-21 74.7 0.0 1.1e-20 74.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EAQ83483.1 - 4.9e-08 33.1 0.0 1.1e-07 31.9 0.0 1.5 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 EAQ83483.1 - 1.4e-05 24.3 0.0 1.9e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EAQ83483.1 - 0.0012 18.4 0.0 0.0017 17.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 EAQ83483.1 - 0.022 13.9 0.0 0.045 12.9 0.0 1.5 1 0 0 1 1 1 0 Male sterility protein Polysacc_synt_2 PF02719.15 EAQ83483.1 - 0.097 11.8 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF1776 PF08643.10 EAQ83483.1 - 0.1 11.9 0.0 0.48 9.7 0.0 1.8 1 1 1 2 2 2 0 Fungal family of unknown function (DUF1776) FMO-like PF00743.19 EAQ83484.1 - 1.2e-05 23.9 0.0 1.9e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 EAQ83484.1 - 0.0051 16.0 0.0 0.013 14.7 0.0 1.6 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 EAQ83484.1 - 0.0069 15.7 0.0 0.015 14.5 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EAQ83484.1 - 0.021 15.0 0.0 1.4 9.2 0.0 2.6 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 EAQ83484.1 - 0.026 13.6 0.1 0.041 13.0 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Zn_peptidase_2 PF04298.12 EAQ83484.1 - 0.032 13.6 0.0 0.054 12.9 0.0 1.2 1 0 0 1 1 1 0 Putative neutral zinc metallopeptidase PIF1 PF05970.14 EAQ83485.1 - 7.5e-07 28.6 0.1 1.3e-06 27.9 0.1 1.2 1 0 0 1 1 1 1 PIF1-like helicase UvrD_C_2 PF13538.6 EAQ83485.1 - 0.0067 16.2 0.0 0.02 14.7 0.0 1.9 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Ndc1_Nup PF09531.10 EAQ83486.1 - 0.66 8.6 4.4 0.75 8.4 4.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SOG2 PF10428.9 EAQ83486.1 - 5.9 6.0 15.4 8 5.5 15.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Fungal_trans PF04082.18 EAQ83487.1 - 1.3e-24 86.7 0.0 1.9e-24 86.1 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ank_2 PF12796.7 EAQ83488.1 - 1.8e-30 105.3 14.2 3.9e-14 53.0 0.9 2.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAQ83488.1 - 1.2e-19 70.4 12.9 1.5e-08 35.0 0.6 4.2 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAQ83488.1 - 5.1e-16 57.1 5.2 0.0011 19.3 0.1 4.6 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 EAQ83488.1 - 3.6e-14 52.7 10.4 0.00026 21.2 0.3 4.3 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 EAQ83488.1 - 1.9e-12 47.0 14.9 4.9e-05 23.6 0.3 4.2 4 0 0 4 4 4 3 Ankyrin repeat VIT PF08487.10 EAQ83488.1 - 0.049 13.8 0.3 0.094 12.9 0.3 1.5 1 0 0 1 1 1 0 Vault protein inter-alpha-trypsin domain PIF1 PF05970.14 EAQ83491.1 - 4.8e-31 108.2 0.0 1.9e-24 86.5 0.0 2.1 2 0 0 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 EAQ83491.1 - 1.1e-10 41.5 0.0 3.1e-10 40.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain Herpes_Helicase PF02689.14 EAQ83491.1 - 2e-05 22.8 0.0 0.00027 19.0 0.0 2.0 2 0 0 2 2 2 1 Helicase AAA_19 PF13245.6 EAQ83491.1 - 0.00016 22.0 0.0 0.00036 20.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 EAQ83491.1 - 0.00016 21.4 0.1 0.00066 19.4 0.0 2.0 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain CorA PF01544.18 EAQ83492.1 - 8.7e-07 28.5 0.2 8.7e-07 28.5 0.2 2.5 3 0 0 3 3 3 1 CorA-like Mg2+ transporter protein PTRF_SDPR PF15237.6 EAQ83492.1 - 0.04 13.5 0.1 0.04 13.5 0.1 2.3 3 0 0 3 3 3 0 PTRF/SDPR family DUF948 PF06103.11 EAQ83492.1 - 0.054 13.7 1.9 0.15 12.3 0.5 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DEAD PF00270.29 EAQ83493.1 - 9e-18 64.6 0.0 1.4e-17 64.0 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EAQ83493.1 - 3.3e-13 50.0 0.0 1.1e-12 48.3 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EAQ83493.1 - 1.2e-07 32.0 0.0 2.7e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PhoH PF02562.16 EAQ83493.1 - 0.014 14.9 0.0 0.026 14.0 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Herpes_IE68 PF02479.16 EAQ83493.1 - 0.14 11.8 0.0 0.37 10.4 0.0 1.6 1 0 0 1 1 1 0 Herpesvirus immediate early protein Inositol_P PF00459.25 EAQ83495.1 - 1.3e-22 80.6 1.4 3.6e-22 79.2 0.0 2.3 2 1 0 2 2 2 1 Inositol monophosphatase family TFIIA PF03153.13 EAQ83495.1 - 1.9 8.4 18.4 2.5 8.0 18.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 EAQ83495.1 - 4.1 6.1 11.2 6 5.5 11.2 1.3 1 0 0 1 1 1 0 Presenilin Macoilin PF09726.9 EAQ83495.1 - 4.4 5.7 15.0 5.5 5.4 15.0 1.1 1 0 0 1 1 1 0 Macoilin family LysM PF01476.20 EAQ83496.1 - 4.4e-16 58.7 2.1 6.3e-06 26.2 0.0 5.8 6 0 0 6 6 6 4 LysM domain LRV_FeS PF05484.11 EAQ83496.1 - 0.027 14.5 0.6 2.1 8.4 0.0 3.8 4 0 0 4 4 4 0 LRV protein FeS4 cluster Glyco_hydro_18 PF00704.28 EAQ83497.1 - 9.4e-60 202.9 0.1 1.3e-59 202.5 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 EAQ83497.1 - 3.6e-10 40.1 20.1 8.2e-09 35.8 7.5 2.5 2 0 0 2 2 2 2 Chitin recognition protein Reprolysin_5 PF13688.6 EAQ83498.1 - 0.0032 17.7 0.2 0.0077 16.4 0.1 1.7 2 0 0 2 2 2 1 Metallo-peptidase family M12 Astacin PF01400.24 EAQ83498.1 - 0.013 15.1 0.1 0.084 12.5 0.2 2.0 2 0 0 2 2 2 0 Astacin (Peptidase family M12A) Reprolysin_3 PF13582.6 EAQ83498.1 - 0.053 14.0 0.1 0.1 13.1 0.1 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 EAQ83498.1 - 0.072 12.9 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Matrixin Reprolysin_2 PF13574.6 EAQ83498.1 - 0.1 12.5 0.4 0.19 11.6 0.4 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Fungal_lectin_2 PF18647.1 EAQ83499.1 - 1.7e-33 115.1 0.4 3.7e-33 114.0 0.1 1.8 2 0 0 2 2 2 1 Alpha-galactosyl-binding fungal lectin Lipase_GDSL_2 PF13472.6 EAQ83499.1 - 1.1e-07 32.4 0.6 3.6e-06 27.5 0.1 2.4 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EAQ83499.1 - 4.9e-05 23.4 0.0 0.00012 22.1 0.0 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase MFS_1 PF07690.16 EAQ83500.1 - 7.3e-24 84.3 49.4 6.4e-16 58.2 24.1 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EAQ83500.1 - 7.6e-07 27.9 24.9 7.6e-07 27.9 24.9 1.5 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF1962 PF09227.10 EAQ83501.1 - 3.1e-38 129.9 21.0 3.8e-38 129.7 21.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1962) COesterase PF00135.28 EAQ83502.1 - 1.1e-51 176.2 0.0 6.3e-39 134.2 0.0 2.3 1 1 2 3 3 3 2 Carboxylesterase family Abhydrolase_3 PF07859.13 EAQ83502.1 - 3.1e-06 27.2 0.0 7e-06 26.0 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Kelch_4 PF13418.6 EAQ83503.1 - 0.0025 17.8 0.0 0.0044 17.0 0.0 1.4 1 0 0 1 1 1 1 Galactose oxidase, central domain Kelch_3 PF13415.6 EAQ83503.1 - 0.011 16.0 0.1 0.069 13.5 0.0 2.1 2 0 0 2 2 2 0 Galactose oxidase, central domain Kelch_1 PF01344.25 EAQ83503.1 - 0.013 15.0 0.0 0.023 14.3 0.0 1.4 1 0 0 1 1 1 0 Kelch motif Kelch_2 PF07646.15 EAQ83503.1 - 0.016 15.2 0.0 0.024 14.6 0.0 1.3 1 0 0 1 1 1 0 Kelch motif Kelch_6 PF13964.6 EAQ83503.1 - 0.034 14.4 0.0 0.057 13.7 0.0 1.4 1 0 0 1 1 1 0 Kelch motif Kelch_5 PF13854.6 EAQ83503.1 - 0.1 12.6 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Kelch motif EpsG PF14897.6 EAQ83504.1 - 0.055 12.8 12.8 0.086 12.1 12.8 1.3 1 0 0 1 1 1 0 EpsG family DUF1180 PF06679.12 EAQ83504.1 - 0.46 10.9 1.3 1.9 8.9 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) DUF4271 PF14093.6 EAQ83504.1 - 0.96 9.3 14.1 1.3 8.9 14.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4271) OAD_gamma PF04277.13 EAQ83504.1 - 1.3 9.7 4.0 21 5.8 0.0 2.5 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain LptF_LptG PF03739.14 EAQ83504.1 - 1.8 7.4 12.9 0.044 12.6 5.9 1.7 1 1 1 2 2 2 0 Lipopolysaccharide export system permease LptF/LptG DUF3043 PF11241.8 EAQ83504.1 - 3.5 7.7 7.5 0.73 9.9 1.4 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3043) DUF4234 PF14018.6 EAQ83504.1 - 6.1 7.0 9.3 3.8 7.7 0.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4234) His_Phos_1 PF00300.22 EAQ83507.1 - 2.9e-05 23.9 0.0 0.0017 18.1 0.0 2.1 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) RPE65 PF03055.15 EAQ83508.1 - 1.3e-40 140.0 0.0 1.6e-40 139.7 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein bZIP_2 PF07716.15 EAQ83509.1 - 0.055 13.6 7.0 0.18 11.9 7.0 1.9 1 0 0 1 1 1 0 Basic region leucine zipper cwf18 PF08315.12 EAQ83509.1 - 0.15 12.7 4.2 0.13 13.0 0.7 2.4 3 0 0 3 3 3 0 cwf18 pre-mRNA splicing factor CDH-cyt PF16010.5 EAQ83510.1 - 1.4e-10 41.2 0.2 2.1e-10 40.6 0.2 1.2 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase Bclt PF15318.6 EAQ83510.1 - 0.17 11.7 0.0 0.31 10.9 0.0 1.3 1 0 0 1 1 1 0 Putative Bcl-2 like protein of testis Pro-kuma_activ PF09286.11 EAQ83511.1 - 4.2e-10 40.1 0.0 7.4e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain OPT PF03169.15 EAQ83512.1 - 3.4e-52 177.9 33.2 4.8e-52 177.4 33.2 1.2 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Peptidase_A24 PF01478.18 EAQ83512.1 - 0.0073 16.7 0.5 0.0073 16.7 0.5 2.7 3 0 0 3 3 3 1 Type IV leader peptidase family DUF3328 PF11807.8 EAQ83513.1 - 1.7e-54 184.9 0.0 2.1e-54 184.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Pro-kuma_activ PF09286.11 EAQ83514.1 - 7e-09 36.1 0.1 5.8e-07 29.9 0.1 2.4 1 1 1 2 2 2 2 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 EAQ83514.1 - 0.00059 19.2 0.0 0.0016 17.8 0.0 1.6 1 1 0 1 1 1 1 Subtilase family DUF3328 PF11807.8 EAQ83515.1 - 1.5e-21 77.2 5.6 4.2e-20 72.5 3.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF3328) CBM_26 PF16824.5 EAQ83516.1 - 0.00039 20.6 17.3 10 6.3 0.2 6.4 1 1 11 12 12 12 2 C-terminal carbohydrate-binding module DUF5622 PF18533.1 EAQ83516.1 - 0.00049 20.2 13.2 20 5.4 0.4 6.4 1 1 3 5 5 5 3 Domain of unknown function (DUF5622) Tom37 PF10568.9 EAQ83516.1 - 2.6 8.4 4.6 29 5.0 1.1 2.8 1 1 1 2 2 2 0 Outer mitochondrial membrane transport complex protein DUF4927 PF16279.5 EAQ83516.1 - 9.7 7.3 7.0 73 4.5 0.1 4.1 1 1 4 5 5 5 0 Domain of unknown function (DUF4927) MFS_1 PF07690.16 EAQ83517.1 - 2.2e-52 178.1 33.7 2.2e-52 178.1 33.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EAQ83517.1 - 1.4e-11 44.0 17.2 1.8e-10 40.3 8.2 2.6 2 1 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.13 EAQ83517.1 - 9.9e-06 24.2 3.9 1.6e-05 23.6 3.9 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 EAQ83517.1 - 0.0024 16.3 1.0 0.0058 15.0 0.7 1.7 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.7 EAQ83517.1 - 0.017 14.0 0.5 0.017 14.0 0.5 2.5 1 1 0 2 2 2 0 MFS_1 like family DAO PF01266.24 EAQ83518.1 - 5.9e-35 121.5 0.0 7e-35 121.2 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EAQ83518.1 - 7.2e-10 38.5 0.1 3.6e-09 36.2 0.1 1.9 1 1 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 EAQ83518.1 - 2.7e-07 29.6 0.5 3.1e-05 22.8 0.1 2.2 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_3 PF13738.6 EAQ83518.1 - 6.7e-06 25.6 0.2 0.00076 18.8 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EAQ83518.1 - 1e-05 25.0 0.5 0.00011 21.5 0.5 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EAQ83518.1 - 1.1e-05 24.9 0.2 6.7e-05 22.2 0.1 2.0 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 EAQ83518.1 - 1.5e-05 25.2 0.1 4.5e-05 23.6 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 EAQ83518.1 - 8.2e-05 22.1 0.5 0.00021 20.8 0.5 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 EAQ83518.1 - 0.0002 20.6 0.2 0.0025 16.9 0.1 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox PF00070.27 EAQ83518.1 - 0.0024 18.4 0.1 0.0052 17.3 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EAQ83518.1 - 0.0074 15.5 0.0 0.58 9.2 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.12 EAQ83518.1 - 0.025 13.6 0.1 0.038 13.1 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_7 PF13241.6 EAQ83518.1 - 0.042 14.3 0.1 0.11 13.0 0.0 1.7 2 0 0 2 2 2 0 Putative NAD(P)-binding AlaDh_PNT_C PF01262.21 EAQ83518.1 - 0.053 12.8 0.4 0.097 11.9 0.4 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 EAQ83518.1 - 0.086 12.1 0.0 0.26 10.5 0.0 1.7 2 0 0 2 2 2 0 FAD binding domain Amino_oxidase PF01593.24 EAQ83519.1 - 6.1e-34 118.1 0.0 7.8e-34 117.7 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EAQ83519.1 - 2.3e-09 37.4 0.0 6.4e-09 35.9 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EAQ83519.1 - 0.056 12.7 0.0 0.16 11.2 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ABC_tran PF00005.27 EAQ83520.1 - 9.4e-51 171.9 0.0 2.7e-28 99.2 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EAQ83520.1 - 6.4e-45 153.9 29.7 2.2e-30 106.3 14.0 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 EAQ83520.1 - 3.7e-08 33.1 1.5 0.011 15.2 0.0 3.7 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EAQ83520.1 - 8.4e-06 25.8 0.0 0.036 14.0 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EAQ83520.1 - 2.6e-05 24.3 0.2 0.15 12.2 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 EAQ83520.1 - 7.1e-05 22.5 0.4 0.057 13.2 0.2 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 EAQ83520.1 - 0.00013 21.9 0.5 0.011 15.6 0.0 2.8 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system DUF87 PF01935.17 EAQ83520.1 - 0.0002 21.5 0.8 0.076 13.1 0.0 2.3 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_23 PF13476.6 EAQ83520.1 - 0.00023 21.8 1.0 0.03 14.8 0.2 2.3 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 EAQ83520.1 - 0.00039 20.5 0.5 0.02 15.0 0.0 2.4 2 0 0 2 2 2 1 Dynamin family T2SSE PF00437.20 EAQ83520.1 - 0.0052 15.9 0.0 0.03 13.4 0.0 2.1 2 0 0 2 2 2 1 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 EAQ83520.1 - 0.0062 15.9 0.1 0.69 9.2 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_22 PF13401.6 EAQ83520.1 - 0.018 15.3 1.6 3.8 7.8 0.1 2.9 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EAQ83520.1 - 0.019 15.3 1.5 5 7.5 0.1 2.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_25 PF13481.6 EAQ83520.1 - 0.024 14.2 0.1 4 7.0 0.1 3.0 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EAQ83520.1 - 0.14 11.9 0.1 2.7 7.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 EAQ83520.1 - 0.16 11.2 0.3 11 5.2 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin Adeno_IVa2 PF02456.15 EAQ83520.1 - 0.25 10.1 0.1 15 4.2 0.1 2.2 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_15 PF13175.6 EAQ83520.1 - 0.97 9.1 3.1 0.35 10.5 0.5 1.5 2 0 0 2 2 2 0 AAA ATPase domain Tyrosinase PF00264.20 EAQ83522.1 - 2.8e-36 125.9 0.0 4e-36 125.4 0.0 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase Chorion_3 PF05387.11 EAQ83525.1 - 0.22 11.1 7.5 0.3 10.7 7.5 1.1 1 0 0 1 1 1 0 Chorion family 3 K_channel_TID PF07941.11 EAQ83525.1 - 9.1 6.8 24.8 0.66 10.5 19.1 2.0 1 1 1 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain adh_short_C2 PF13561.6 EAQ83526.1 - 1.1e-53 182.2 1.8 1.5e-53 181.8 1.8 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EAQ83526.1 - 2.1e-45 154.6 3.1 2.6e-45 154.3 3.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EAQ83526.1 - 4.1e-12 46.4 1.1 5.2e-12 46.0 1.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EAQ83526.1 - 0.00062 19.3 0.4 0.022 14.2 0.4 2.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family AdoHcyase_NAD PF00670.21 EAQ83526.1 - 0.014 15.5 0.5 0.042 13.9 0.3 1.8 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain THF_DHG_CYH_C PF02882.19 EAQ83526.1 - 0.082 12.2 0.1 0.21 10.9 0.1 1.7 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain N6_Mtase PF02384.16 EAQ83526.1 - 0.14 11.4 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 N-6 DNA Methylase Fungal_trans PF04082.18 EAQ83527.1 - 4.4e-11 42.3 0.0 7.1e-11 41.6 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain NAD_binding_10 PF13460.6 EAQ83528.1 - 2.6e-13 50.3 0.0 1.4e-12 47.9 0.0 1.8 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 EAQ83528.1 - 1.6e-10 41.0 0.0 2.1e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 EAQ83528.1 - 1.2e-07 31.4 0.0 4.6e-07 29.5 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.10 EAQ83528.1 - 0.0014 18.6 0.0 0.0022 18.0 0.0 1.4 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.17 EAQ83528.1 - 0.0023 18.5 0.0 0.0043 17.6 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3Beta_HSD PF01073.19 EAQ83528.1 - 0.0085 15.1 0.0 0.012 14.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 EAQ83528.1 - 0.009 15.1 0.2 0.15 11.1 0.0 2.1 2 0 0 2 2 2 1 RmlD substrate binding domain Sacchrp_dh_NADP PF03435.18 EAQ83528.1 - 0.011 16.0 0.1 0.021 15.1 0.1 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain DapB_N PF01113.20 EAQ83528.1 - 0.02 15.0 0.1 0.035 14.2 0.1 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Polysacc_synt_2 PF02719.15 EAQ83528.1 - 0.21 10.7 0.0 0.31 10.1 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein zf-C2H2 PF00096.26 EAQ83529.1 - 1.4e-06 28.4 11.5 0.00014 22.1 5.4 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EAQ83529.1 - 2.9e-05 24.3 5.2 0.0045 17.4 0.2 2.7 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_11 PF16622.5 EAQ83529.1 - 0.00032 20.4 5.6 0.0074 16.0 0.7 2.5 2 0 0 2 2 2 2 zinc-finger C2H2-type zf-C2H2_4 PF13894.6 EAQ83529.1 - 0.0026 18.4 10.3 0.075 13.9 4.5 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 EAQ83529.1 - 0.085 12.9 5.9 5.5 7.1 2.4 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-UBR PF02207.20 EAQ83529.1 - 0.11 12.7 2.4 0.2 11.8 2.4 1.4 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) Zn_ribbon_SprT PF17283.2 EAQ83529.1 - 3.9 7.5 9.5 18 5.3 8.1 2.5 1 1 1 2 2 2 0 SprT-like zinc ribbon domain ECH_1 PF00378.20 EAQ83530.1 - 1e-27 97.0 0.0 3.6e-21 75.6 0.0 3.2 1 1 1 3 3 3 2 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EAQ83530.1 - 2.7e-18 66.6 0.3 1.1e-15 58.0 0.0 2.2 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase WSC PF01822.19 EAQ83530.1 - 1.9e-11 44.0 6.5 1.9e-11 44.0 6.5 1.9 2 0 0 2 2 2 1 WSC domain SKG6 PF08693.10 EAQ83530.1 - 5.8e-08 32.0 3.1 1.4e-07 30.8 3.1 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF2076 PF09849.9 EAQ83530.1 - 0.063 13.3 0.1 0.13 12.2 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) CsbD PF05532.12 EAQ83531.1 - 0.0052 16.7 15.5 0.089 12.7 15.5 2.9 1 1 0 1 1 1 1 CsbD-like Apolipoprotein PF01442.18 EAQ83531.1 - 0.074 12.9 5.2 0.18 11.6 5.2 1.8 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Dicty_REP PF05086.12 EAQ83531.1 - 0.44 8.5 5.2 0.44 8.5 5.2 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein REF PF05755.12 EAQ83531.1 - 0.64 9.8 3.7 2.3 8.0 3.5 1.9 1 1 0 1 1 1 0 Rubber elongation factor protein (REF) Mucin PF01456.17 EAQ83531.1 - 1.2 9.1 21.4 2.2 8.3 21.4 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein ISG65-75 PF11727.8 EAQ83531.1 - 2.1 7.5 10.1 2.1 7.5 9.4 1.4 1 1 0 1 1 1 0 Invariant surface glycoprotein YtxH PF12732.7 EAQ83531.1 - 3.2 8.4 11.5 3.4 8.3 2.6 2.6 1 1 1 2 2 2 0 YtxH-like protein Dehydratase_hem PF13816.6 EAQ83532.1 - 4.4e-101 338.3 0.0 7.8e-101 337.5 0.0 1.3 1 0 0 1 1 1 1 Haem-containing dehydratase APH PF01636.23 EAQ83532.1 - 1.7e-10 41.2 0.1 2.1e-09 37.6 0.1 2.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF4188 PF13826.6 EAQ83532.1 - 0.00011 22.6 0.1 0.21 11.9 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF4188) Choline_kinase PF01633.20 EAQ83532.1 - 0.00011 21.9 0.0 0.0002 21.0 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Fructosamin_kin PF03881.14 EAQ83532.1 - 0.015 14.5 0.0 0.025 13.8 0.0 1.2 1 0 0 1 1 1 0 Fructosamine kinase Pkinase PF00069.25 EAQ83532.1 - 0.25 10.7 0.0 0.44 9.9 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain CN_hydrolase PF00795.22 EAQ83533.1 - 2e-41 142.0 0.0 2.4e-41 141.8 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase DUF4812 PF16071.5 EAQ83534.1 - 0.039 13.7 0.2 0.16 11.8 0.2 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4812) VSP PF03302.13 EAQ83535.1 - 0.077 11.8 0.1 0.1 11.5 0.1 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein AP_endonuc_2 PF01261.24 EAQ83536.1 - 0.038 13.4 0.1 0.084 12.3 0.1 1.5 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel DUF936 PF06075.12 EAQ83536.1 - 0.14 11.1 11.3 0.17 10.8 11.3 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) FAM220 PF15487.6 EAQ83536.1 - 1.9 8.1 6.5 2.4 7.7 6.5 1.2 1 0 0 1 1 1 0 FAM220 family Apt1 PF10351.9 EAQ83536.1 - 3.5 6.4 11.1 4.2 6.1 11.1 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain KAR9 PF08580.10 EAQ83536.1 - 7.7 4.9 22.8 9.4 4.6 22.8 1.0 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Macoilin PF09726.9 EAQ83536.1 - 9.2 4.7 7.9 11 4.5 7.9 1.0 1 0 0 1 1 1 0 Macoilin family MpPF1 PF07668.11 EAQ83537.1 - 0.018 14.3 0.2 0.027 13.7 0.2 1.2 1 0 0 1 1 1 0 M penetrans paralogue family 1 RPW8 PF05659.11 EAQ83537.1 - 0.025 14.3 2.1 0.55 9.9 0.0 2.6 3 0 0 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 MitMem_reg PF13012.6 EAQ83537.1 - 0.037 14.5 1.7 0.062 13.7 0.6 2.0 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function Med16 PF11635.8 EAQ83537.1 - 0.045 11.7 0.1 0.066 11.1 0.1 1.1 1 0 0 1 1 1 0 Mediator complex subunit 16 Snapin_Pallidin PF14712.6 EAQ83537.1 - 0.22 12.0 8.0 0.17 12.4 4.5 2.4 2 0 0 2 2 2 0 Snapin/Pallidin UPF0449 PF15136.6 EAQ83537.1 - 0.44 11.0 2.8 0.46 11.0 0.3 2.3 3 0 0 3 3 3 0 Uncharacterised protein family UPF0449 TF_AP-2 PF03299.14 EAQ83537.1 - 0.49 10.3 5.5 31 4.5 0.0 3.2 2 1 1 3 3 3 0 Transcription factor AP-2 FTA4 PF13093.6 EAQ83537.1 - 2.4 8.0 8.8 52 3.7 5.7 2.9 2 1 0 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 VID27 PF08553.10 EAQ83539.1 - 1.3e-190 633.0 0.0 1.8e-190 632.5 0.0 1.1 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain VID27_N PF17748.1 EAQ83539.1 - 5.2e-76 254.3 0.3 5.2e-76 254.3 0.3 2.7 2 0 0 2 2 2 1 VID27 N-terminal region VID27_PH PF17747.1 EAQ83539.1 - 3.6e-44 149.5 1.5 8.3e-44 148.3 1.1 1.8 2 0 0 2 2 2 1 VID27 PH-like domain DNA_pol_phi PF04931.13 EAQ83539.1 - 1.6 6.7 11.2 2.9 5.9 11.2 1.3 1 0 0 1 1 1 0 DNA polymerase phi TRAP_alpha PF03896.16 EAQ83539.1 - 5.3 6.2 9.3 23 4.1 9.0 2.1 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Prenylcys_lyase PF07156.14 EAQ83540.1 - 5.6e-85 285.6 0.0 7.3e-85 285.2 0.0 1.0 1 0 0 1 1 1 1 Prenylcysteine lyase NAD_binding_8 PF13450.6 EAQ83540.1 - 1.4e-12 47.6 0.1 5.1e-12 45.9 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 EAQ83540.1 - 1.1e-10 41.4 0.0 3.1e-10 39.9 0.0 1.7 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase DAO PF01266.24 EAQ83540.1 - 5.8e-06 26.1 0.2 0.00056 19.6 0.2 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EAQ83540.1 - 0.0008 18.7 0.1 0.0035 16.6 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EAQ83540.1 - 0.0041 16.4 0.2 0.79 8.9 0.1 2.3 2 0 0 2 2 2 2 Thi4 family NAD_binding_9 PF13454.6 EAQ83540.1 - 0.0066 16.4 0.1 0.016 15.2 0.1 1.7 1 0 0 1 1 1 1 FAD-NAD(P)-binding FAD_oxidored PF12831.7 EAQ83540.1 - 0.026 13.9 0.7 4.9 6.4 0.3 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EAQ83540.1 - 0.03 13.6 0.1 0.05 12.9 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain FAD_binding_2 PF00890.24 EAQ83540.1 - 0.085 11.9 1.8 0.14 11.2 1.8 1.3 1 0 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.14 EAQ83540.1 - 0.097 11.5 0.1 0.14 11.0 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox PF00070.27 EAQ83540.1 - 0.11 13.0 1.9 1.4 9.6 0.3 2.9 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Cpn60_TCP1 PF00118.24 EAQ83541.1 - 3.7e-132 441.4 2.6 3.1e-106 355.9 0.0 2.1 1 1 1 2 2 2 2 TCP-1/cpn60 chaperonin family Herpes_UL6 PF01763.16 EAQ83541.1 - 0.1 11.1 0.0 0.15 10.5 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL6 like PDCD2_C PF04194.13 EAQ83542.1 - 1.7e-47 161.7 0.1 6.4e-47 159.9 0.0 1.9 2 0 0 2 2 2 1 Programmed cell death protein 2, C-terminal putative domain CSN8_PSD8_EIF3K PF10075.9 EAQ83543.1 - 3.1e-28 98.6 0.0 5.1e-28 97.9 0.0 1.3 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family LcrV PF04792.12 EAQ83543.1 - 0.11 11.7 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 V antigen (LcrV) protein DNA_ligase_A_M PF01068.21 EAQ83544.1 - 1.2e-50 172.0 0.0 4.4e-48 163.6 0.0 2.2 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 EAQ83544.1 - 6.9e-23 81.8 0.0 1.3e-22 81.0 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 EAQ83544.1 - 0.00042 20.9 0.0 0.011 16.3 0.0 3.0 3 0 0 3 3 3 1 ATP dependent DNA ligase C terminal region Aldose_epim PF01263.20 EAQ83545.1 - 4.7e-58 196.9 0.0 5.4e-58 196.7 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Shugoshin_N PF07558.11 EAQ83546.1 - 0.018 14.9 2.4 0.083 12.8 0.8 2.3 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region RdRP_5 PF07925.11 EAQ83546.1 - 0.07 10.5 0.0 0.08 10.3 0.0 1.0 1 0 0 1 1 1 0 Reovirus RNA-dependent RNA polymerase lambda 3 DUF3275 PF11679.8 EAQ83546.1 - 0.075 13.0 1.6 0.089 12.8 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) NARP1 PF12569.8 EAQ83546.1 - 0.65 8.8 5.2 0.93 8.3 5.2 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Rrn6 PF10214.9 EAQ83546.1 - 1.1 7.7 6.2 1.1 7.7 6.2 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor SRP-alpha_N PF04086.13 EAQ83546.1 - 9.6 6.0 9.7 12 5.7 9.7 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal MULE PF10551.9 EAQ83547.1 - 7.8e-14 51.9 0.0 1.7e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 MULE transposase domain FAR1 PF03101.15 EAQ83547.1 - 4.7e-05 24.0 0.2 0.00021 21.9 0.0 1.9 2 0 0 2 2 2 1 FAR1 DNA-binding domain DUF1917 PF08939.10 EAQ83548.1 - 0.002 18.1 0.0 0.0053 16.7 0.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF1917) DUF2508 PF10704.9 EAQ83548.1 - 0.42 10.8 1.4 1.3 9.3 0.1 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF2508) MAP65_ASE1 PF03999.12 EAQ83548.1 - 0.79 8.3 1.8 0.61 8.7 0.0 1.5 2 0 0 2 2 2 0 Microtubule associated protein (MAP65/ASE1 family) AAL_decarboxy PF03306.13 EAQ83549.1 - 2.5e-80 268.9 0.6 2.9e-80 268.7 0.6 1.0 1 0 0 1 1 1 1 Alpha-acetolactate decarboxylase HET PF06985.11 EAQ83550.1 - 1.8e-30 106.3 0.7 3e-30 105.5 0.7 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) UvrD_C_2 PF13538.6 EAQ83552.1 - 0.0055 16.5 0.0 0.038 13.8 0.0 2.4 2 1 0 2 2 2 1 UvrD-like helicase C-terminal domain p450 PF00067.22 EAQ83553.1 - 2.8e-48 164.8 0.0 4.8e-48 164.1 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 TRP PF06011.12 EAQ83554.1 - 7.3e-23 81.0 15.8 3.9e-14 52.2 3.6 3.1 2 1 0 2 2 2 2 Transient receptor potential (TRP) ion channel Pilin_N PF07790.11 EAQ83554.1 - 0.046 14.6 0.0 0.18 12.8 0.0 2.0 1 0 0 1 1 1 0 Archaeal Type IV pilin, N-terminal DUF3328 PF11807.8 EAQ83556.1 - 6.1e-44 150.4 5.0 7.2e-44 150.2 5.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) F-box-like PF12937.7 EAQ83558.1 - 0.27 11.1 2.9 0.29 11.1 0.0 2.5 4 0 0 4 4 4 0 F-box-like DUF3767 PF12597.8 EAQ83560.1 - 8.9e-37 125.0 0.0 8.9e-37 125.0 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3767) DUF1744 PF08490.12 EAQ83561.1 - 1.9e-132 441.6 0.2 1.8e-123 412.1 0.0 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 EAQ83561.1 - 2e-78 263.9 0.1 3.3e-78 263.2 0.1 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 EAQ83561.1 - 1.4e-13 50.4 0.1 4.9e-11 42.0 0.0 3.2 3 1 0 3 3 3 2 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 EAQ83561.1 - 5.9e-09 35.9 0.1 1.5e-08 34.5 0.1 1.6 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 EAQ83561.1 - 3.9e-06 26.9 0.0 1.2e-05 25.3 0.0 1.8 1 0 0 1 1 1 1 RNase_H superfamily MFS_1 PF07690.16 EAQ83563.1 - 2.9e-45 154.7 56.7 2.9e-45 154.7 56.7 2.1 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EAQ83563.1 - 1e-17 63.9 31.4 1.8e-17 63.0 31.4 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EAQ83563.1 - 2.1e-12 46.6 12.9 2.1e-12 46.6 12.9 3.3 3 1 1 4 4 4 1 Sugar (and other) transporter ATG22 PF11700.8 EAQ83563.1 - 5e-05 22.1 3.2 5e-05 22.1 3.2 3.4 2 1 2 4 4 4 1 Vacuole effluxer Atg22 like OATP PF03137.20 EAQ83563.1 - 0.00024 19.5 2.0 0.00024 19.5 2.0 2.7 3 1 0 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family DUF829 PF05705.14 EAQ83564.1 - 1.6e-19 70.8 0.0 1e-16 61.6 0.1 3.1 2 1 0 2 2 2 2 Eukaryotic protein of unknown function (DUF829) Adeno_E3_CR2 PF02439.15 EAQ83565.1 - 0.00028 20.6 0.0 0.00045 19.9 0.0 1.2 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 SKG6 PF08693.10 EAQ83565.1 - 0.0008 18.8 3.9 0.0012 18.3 3.9 1.2 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Phage_holin_2_1 PF04971.12 EAQ83565.1 - 0.0023 17.9 0.7 0.0036 17.3 0.7 1.2 1 0 0 1 1 1 1 Bacteriophage P21 holin S DUF3827 PF12877.7 EAQ83565.1 - 0.0058 15.1 0.0 0.0075 14.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3827) Syndecan PF01034.20 EAQ83565.1 - 0.039 13.9 0.1 0.056 13.4 0.1 1.2 1 0 0 1 1 1 0 Syndecan domain EphA2_TM PF14575.6 EAQ83565.1 - 0.047 14.6 0.0 0.064 14.1 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF2207 PF09972.9 EAQ83565.1 - 0.071 11.9 0.0 0.085 11.6 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) ECSCR PF15820.5 EAQ83565.1 - 0.14 12.0 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator FixQ PF05545.11 EAQ83565.1 - 0.18 11.8 0.0 0.31 11.1 0.0 1.4 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ TMEM154 PF15102.6 EAQ83565.1 - 0.19 11.6 0.0 0.25 11.2 0.0 1.2 1 0 0 1 1 1 0 TMEM154 protein family Gram_pos_anchor PF00746.21 EAQ83565.1 - 0.22 11.5 0.2 0.37 10.8 0.2 1.3 1 0 0 1 1 1 0 LPXTG cell wall anchor motif Collectrin PF16959.5 EAQ83565.1 - 0.33 10.7 1.2 0.43 10.4 1.2 1.1 1 0 0 1 1 1 0 Renal amino acid transporter Ribosomal_S2 PF00318.20 EAQ83567.1 - 1.5e-62 210.6 0.0 1.6e-61 207.3 0.0 2.3 1 1 0 1 1 1 1 Ribosomal protein S2 CBS PF00571.28 EAQ83567.1 - 4.8e-34 116.6 7.5 1.9e-08 34.6 0.0 6.0 5 1 1 6 6 6 4 CBS domain PB1 PF00564.24 EAQ83567.1 - 1.3e-09 37.8 0.1 4.5e-09 36.1 0.0 2.0 2 0 0 2 2 2 1 PB1 domain zf-H2C2 PF09337.10 EAQ83568.1 - 1.3e-16 60.6 0.9 2.5e-16 59.6 0.9 1.6 1 0 0 1 1 1 1 H2C2 zinc finger Integrase_H2C2 PF17921.1 EAQ83568.1 - 3.5e-13 49.4 0.2 7.4e-13 48.4 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Acetyltransf_1 PF00583.25 EAQ83568.1 - 2.9e-06 27.5 0.0 5.4e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 EAQ83568.1 - 0.0052 16.9 0.0 0.0098 16.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain BSP_II PF05432.11 EAQ83568.1 - 0.015 15.0 14.2 0.024 14.3 14.2 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Acetyltransf_3 PF13302.7 EAQ83568.1 - 0.06 14.0 0.0 0.14 12.9 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EAQ83568.1 - 0.11 13.0 0.1 0.74 10.3 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Dicty_REP PF05086.12 EAQ83568.1 - 0.88 7.5 10.0 1.3 6.9 10.0 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Apt1 PF10351.9 EAQ83568.1 - 2.7 6.7 9.5 3.9 6.2 9.5 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Cpn60_TCP1 PF00118.24 EAQ83569.1 - 7.5e-155 516.3 5.8 8.5e-155 516.1 5.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family GNAT_acetyltran PF12746.7 EAQ83569.1 - 0.1 12.2 1.9 0.13 11.8 0.1 1.9 2 0 0 2 2 2 0 GNAT acetyltransferase Ank_2 PF12796.7 EAQ83570.1 - 2.8e-19 69.5 0.0 1.1e-10 42.0 0.0 5.5 5 1 1 6 6 6 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAQ83570.1 - 2.6e-14 53.4 1.7 2.6e-07 31.1 0.1 5.5 5 1 2 7 7 7 3 Ankyrin repeats (many copies) Ank PF00023.30 EAQ83570.1 - 5.9e-14 51.8 2.3 0.0019 18.6 0.0 5.5 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.6 EAQ83570.1 - 2.3e-13 49.0 3.7 0.042 14.4 0.0 7.6 7 0 0 7 7 7 3 Ankyrin repeat Ank_5 PF13857.6 EAQ83570.1 - 6.3e-11 42.3 0.6 0.0019 18.5 0.0 4.3 2 1 2 4 4 4 3 Ankyrin repeats (many copies) F-box-like PF12937.7 EAQ83570.1 - 2.4e-08 33.7 0.0 1e-07 31.7 0.0 2.2 1 0 0 1 1 1 1 F-box-like Ribosomal_S26e PF01283.19 EAQ83572.1 - 3.9e-53 178.5 8.6 4.6e-53 178.2 8.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e zf_CopZ PF18423.1 EAQ83572.1 - 0.017 15.0 0.4 0.054 13.5 0.0 2.0 2 0 0 2 2 2 0 Zinc binding domain DUF1918 PF08940.11 EAQ83572.1 - 0.047 13.3 0.1 0.085 12.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) DUF4668 PF15701.5 EAQ83572.1 - 0.18 11.6 2.0 0.22 11.3 1.4 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4668) ubiquitin PF00240.23 EAQ83573.1 - 1.5e-34 117.5 0.6 1.7e-34 117.4 0.6 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EAQ83573.1 - 9.5e-17 60.6 0.7 1.1e-16 60.4 0.7 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EAQ83573.1 - 7.3e-06 26.4 0.1 2.9e-05 24.5 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_5 PF18037.1 EAQ83573.1 - 0.0014 18.9 0.1 0.0017 18.6 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 EAQ83573.1 - 0.0018 18.2 0.0 0.0021 17.9 0.0 1.2 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_4 PF18036.1 EAQ83573.1 - 0.0026 17.8 0.3 2 8.5 0.1 2.1 2 0 0 2 2 2 2 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 EAQ83573.1 - 0.0033 17.5 0.1 0.0069 16.5 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EAQ83573.1 - 0.021 15.4 0.0 0.023 15.3 0.0 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Glyco_hydro_18 PF00704.28 EAQ83574.1 - 4.8e-34 118.5 0.5 1.5e-28 100.4 0.0 2.0 1 1 1 2 2 2 2 Glycosyl hydrolases family 18 AP_endonuc_2 PF01261.24 EAQ83574.1 - 0.093 12.2 0.0 0.16 11.3 0.0 1.4 1 1 0 1 1 1 0 Xylose isomerase-like TIM barrel Polysacc_deac_1 PF01522.21 EAQ83575.1 - 1.2e-05 25.2 0.0 2.5e-05 24.2 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide deacetylase DUF4743 PF15916.5 EAQ83575.1 - 0.074 13.0 0.0 2.8 7.9 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4743) DUF2334 PF10096.9 EAQ83575.1 - 0.15 11.7 0.0 6.3 6.4 0.0 2.2 1 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2334) Pkinase PF00069.25 EAQ83576.1 - 9.5e-62 208.7 0.0 1.6e-61 208.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ83576.1 - 2.4e-26 92.6 0.0 4.8e-26 91.6 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_2 PF12796.7 EAQ83576.1 - 5.6e-18 65.3 0.1 2.3e-08 34.5 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAQ83576.1 - 1.2e-12 46.8 0.0 0.18 12.5 0.0 6.1 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.6 EAQ83576.1 - 3.8e-12 46.5 0.2 4.2e-07 30.4 0.0 3.8 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAQ83576.1 - 3.7e-10 39.8 1.5 0.00012 22.2 0.1 3.2 1 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EAQ83576.1 - 8.7e-08 32.3 0.8 0.39 11.2 0.1 5.1 4 0 0 4 4 4 1 Ankyrin repeat NACHT PF05729.12 EAQ83576.1 - 4.3e-07 30.0 0.0 9.8e-07 28.8 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EAQ83576.1 - 2.2e-05 24.9 1.5 0.00012 22.5 0.1 2.7 2 0 0 2 2 2 1 AAA ATPase domain Kinase-like PF14531.6 EAQ83576.1 - 3e-05 23.5 0.0 9.5e-05 21.8 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 EAQ83576.1 - 0.00036 20.0 0.0 0.00078 18.9 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family AAA_22 PF13401.6 EAQ83576.1 - 0.0012 19.1 0.3 0.014 15.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain Pkinase_fungal PF17667.1 EAQ83576.1 - 0.0022 16.8 0.0 0.004 16.0 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase AAA_33 PF13671.6 EAQ83576.1 - 0.0055 16.9 0.1 0.08 13.1 0.0 3.0 3 0 0 3 3 3 1 AAA domain APH PF01636.23 EAQ83576.1 - 0.087 12.7 1.4 1.1 9.1 0.1 2.8 2 1 1 3 3 3 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 EAQ83576.1 - 0.25 10.3 0.0 0.41 9.6 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Annexin PF00191.20 EAQ83577.1 - 1.7e-50 168.9 4.8 2.5e-15 56.3 0.1 4.2 4 0 0 4 4 4 4 Annexin DUF2255 PF10012.9 EAQ83577.1 - 0.045 13.9 0.3 1.6 8.9 0.1 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2255) Apo-CII PF05355.11 EAQ83577.1 - 0.11 12.7 0.5 0.31 11.2 0.1 1.9 2 0 0 2 2 2 0 Apolipoprotein C-II Vesiculo_matrix PF06326.12 EAQ83577.1 - 0.11 12.3 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Vesiculovirus matrix protein ANAPC4 PF12896.7 EAQ83577.1 - 0.15 11.6 0.1 7.7 5.9 0.0 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 4 RepB-RCR_reg PF10723.9 EAQ83577.1 - 0.18 11.8 0.0 0.54 10.2 0.0 1.7 2 0 0 2 2 2 0 Replication regulatory protein RepB PIF1 PF05970.14 EAQ83579.1 - 0.00023 20.4 0.0 0.00038 19.7 0.0 1.3 1 0 0 1 1 1 1 PIF1-like helicase UvrD_C_2 PF13538.6 EAQ83579.1 - 0.0047 16.7 0.0 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain DUF1043 PF06295.12 EAQ83579.1 - 0.19 11.7 3.9 2 8.4 1.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) Herpes_Helicase PF02689.14 EAQ83579.1 - 0.32 8.9 0.0 0.47 8.3 0.0 1.1 1 0 0 1 1 1 0 Helicase DUF3884 PF13024.6 EAQ83580.1 - 0.032 13.8 1.1 0.28 10.8 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3884) DUF4473 PF14747.6 EAQ83580.1 - 0.053 14.1 0.0 0.066 13.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4473) LVIVD PF08309.11 EAQ83581.1 - 0.00027 20.2 0.4 2.4 7.5 0.0 4.1 4 0 0 4 4 4 2 LVIVD repeat Kelch_1 PF01344.25 EAQ83581.1 - 0.11 12.1 0.1 4.9 6.8 0.0 2.7 2 0 0 2 2 2 0 Kelch motif Adaptin_N PF01602.20 EAQ83582.1 - 1.8e-138 462.4 2.1 2.5e-138 461.9 2.1 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EAQ83582.1 - 1.2e-62 210.7 3.2 2.8e-61 206.3 0.1 3.0 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EAQ83582.1 - 1.8e-16 60.3 0.0 3.1e-07 30.7 0.0 5.2 1 1 4 6 6 6 4 HEAT repeats HEAT PF02985.22 EAQ83582.1 - 4e-11 42.2 5.4 0.0082 16.3 0.0 6.4 8 0 0 8 8 8 2 HEAT repeat HEAT_EZ PF13513.6 EAQ83582.1 - 7.1e-05 23.2 0.3 0.58 10.7 0.0 4.9 4 1 1 5 5 5 1 HEAT-like repeat UNC45-central PF11701.8 EAQ83582.1 - 0.0054 16.7 0.2 0.051 13.5 0.0 2.5 2 0 0 2 2 2 1 Myosin-binding striated muscle assembly central Arm PF00514.23 EAQ83582.1 - 0.0061 16.6 0.9 11 6.2 0.0 5.6 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat RTP1_C1 PF10363.9 EAQ83582.1 - 0.011 15.9 0.5 0.44 10.8 0.0 3.6 2 2 2 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 RIX1 PF08167.12 EAQ83582.1 - 0.02 14.7 0.1 9.5 5.9 0.0 2.7 3 0 0 3 3 3 0 rRNA processing/ribosome biogenesis CLASP_N PF12348.8 EAQ83582.1 - 0.043 13.4 0.1 2.4 7.7 0.0 3.1 2 1 1 3 3 3 0 CLASP N terminal CAAP1 PF15335.6 EAQ83582.1 - 0.058 14.0 0.6 0.23 12.1 0.1 2.3 2 0 0 2 2 2 0 Caspase activity and apoptosis inhibitor 1 Asparaginase_2 PF01112.18 EAQ83584.1 - 4.9e-58 196.6 16.0 5.5e-32 111.0 4.0 2.8 2 1 1 3 3 3 2 Asparaginase p450 PF00067.22 EAQ83585.1 - 2.4e-53 181.5 0.0 3.1e-53 181.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 NMT1 PF09084.11 EAQ83588.1 - 1.4e-08 35.0 0.0 2.9e-08 33.9 0.0 1.5 1 1 0 1 1 1 1 NMT1/THI5 like SBP_bac_3 PF00497.20 EAQ83588.1 - 0.031 13.7 0.0 0.045 13.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 Peptidase_C47 PF05543.13 EAQ83588.1 - 0.089 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Staphopain peptidase C47 Glyco_transf_20 PF00982.21 EAQ83589.1 - 2.9e-164 547.2 0.1 1e-85 288.3 0.0 3.0 1 1 2 3 3 3 3 Glycosyltransferase family 20 Glyco_transf_5 PF08323.11 EAQ83589.1 - 0.073 12.8 0.1 0.24 11.1 0.1 1.8 2 0 0 2 2 2 0 Starch synthase catalytic domain MFS_1 PF07690.16 EAQ83590.1 - 6e-24 84.6 66.2 2.4e-23 82.6 25.0 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EAQ83590.1 - 3e-05 22.7 0.3 3e-05 22.7 0.3 3.2 3 0 0 3 3 3 1 MFS/sugar transport protein Cu-oxidase_2 PF07731.14 EAQ83591.1 - 1.7e-11 44.0 0.2 0.00019 21.2 0.0 3.3 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 EAQ83591.1 - 2e-11 44.0 0.1 1.1e-07 31.9 0.1 2.4 2 0 0 2 2 2 2 Multicopper oxidase Cupredoxin_1 PF13473.6 EAQ83591.1 - 0.0047 17.0 0.0 1 9.5 0.0 2.5 2 0 0 2 2 2 2 Cupredoxin-like domain Copper-bind PF00127.20 EAQ83591.1 - 0.012 16.0 0.0 0.025 15.0 0.0 1.5 1 0 0 1 1 1 0 Copper binding proteins, plastocyanin/azurin family RVT_2 PF07727.14 EAQ83592.1 - 4.5e-11 42.9 0.0 8.2e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 EAQ83592.1 - 2.9e-08 33.9 0.1 1.4e-07 31.7 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.6 EAQ83592.1 - 1.8e-05 24.5 0.4 4.7e-05 23.2 0.4 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain Glyco_hydro_67M PF07488.12 EAQ83593.1 - 2e-144 480.6 0.0 2.8e-144 480.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 middle domain Glyco_hydro_67C PF07477.12 EAQ83593.1 - 4e-87 291.4 0.8 4e-87 291.4 0.8 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 67 C-terminus Glyco_hydro_67N PF03648.14 EAQ83593.1 - 6.4e-30 103.9 0.0 1.3e-29 103.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 N-terminus Glyco_hydro_20b PF02838.15 EAQ83593.1 - 0.021 15.6 0.0 0.059 14.2 0.0 1.7 1 0 0 1 1 1 0 Glycosyl hydrolase family 20, domain 2 ADH_zinc_N_2 PF13602.6 EAQ83594.1 - 1.5e-10 42.2 0.0 2.9e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EAQ83594.1 - 2.9e-08 33.7 0.2 7.3e-08 32.5 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EAQ83594.1 - 2e-07 30.8 0.3 6.9e-07 29.1 0.1 1.9 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain DUF676 PF05057.14 EAQ83595.1 - 0.0013 18.3 0.0 0.0024 17.4 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) SDH_sah PF01972.16 EAQ83595.1 - 0.0027 16.8 0.2 0.042 12.8 0.0 2.6 3 0 0 3 3 3 1 Serine dehydrogenase proteinase Hydrolase_4 PF12146.8 EAQ83595.1 - 0.0031 16.8 0.0 0.007 15.7 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 EAQ83595.1 - 0.026 14.3 0.0 0.044 13.5 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_6 PF12697.7 EAQ83595.1 - 0.056 14.0 0.0 0.12 13.0 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF4913 PF16259.5 EAQ83595.1 - 0.064 13.3 0.1 3.9 7.6 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4913) DUF5633 PF18656.1 EAQ83595.1 - 0.2 11.6 0.2 0.37 10.7 0.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5633) FAD_binding_4 PF01565.23 EAQ83599.1 - 3.5e-24 85.1 1.0 6.8e-24 84.2 1.0 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EAQ83599.1 - 4.8e-12 45.8 0.0 9e-12 44.9 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like Beta-lactamase PF00144.24 EAQ83603.1 - 8.7e-06 25.2 0.1 1.4e-05 24.6 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.8 EAQ83603.1 - 0.00016 22.1 0.1 0.00024 21.5 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) Bac_rhodopsin PF01036.18 EAQ83604.1 - 6e-41 140.5 18.0 7.4e-41 140.2 18.0 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein Heliorhodopsin PF18761.1 EAQ83604.1 - 0.0018 17.6 3.3 0.0024 17.2 3.1 1.6 1 1 0 1 1 1 1 Heliorhodopsin PP2C PF00481.21 EAQ83605.1 - 1.1e-16 61.3 0.0 1.6e-16 60.8 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C HTH_15 PF12324.8 EAQ83605.1 - 0.13 12.2 0.1 0.7 9.9 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain of alkylmercury lyase Gelsolin PF00626.22 EAQ83607.1 - 6.3e-23 80.5 0.0 1.8e-11 43.8 0.0 2.3 2 0 0 2 2 2 2 Gelsolin repeat Meth_synt_2 PF01717.18 EAQ83608.1 - 4.9e-13 49.1 0.0 1e-12 48.0 0.0 1.5 1 1 0 1 1 1 1 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 EAQ83608.1 - 0.032 13.7 0.0 0.076 12.5 0.0 1.7 2 0 0 2 2 2 0 Cobalamin-independent synthase, N-terminal domain Sugar_tr PF00083.24 EAQ83609.1 - 7.3e-29 100.9 6.9 8e-29 100.8 6.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MgtE PF01769.16 EAQ83609.1 - 0.84 10.0 5.4 0.45 10.9 3.3 1.7 1 1 0 1 1 1 0 Divalent cation transporter MFS_1 PF07690.16 EAQ83612.1 - 7.3e-39 133.7 37.1 7.3e-39 133.7 37.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EAQ83612.1 - 6.5e-11 41.8 9.2 6.5e-11 41.8 9.2 2.4 3 0 0 3 3 3 1 Sugar (and other) transporter Ferritin_2 PF13668.6 EAQ83613.1 - 0.018 15.3 0.3 0.34 11.1 0.1 2.2 1 1 1 2 2 2 0 Ferritin-like domain Tri3 PF07428.11 EAQ83614.1 - 0.00071 18.6 0.0 0.0011 18.0 0.0 1.2 1 0 0 1 1 1 1 15-O-acetyltransferase Tri3 MFS_1 PF07690.16 EAQ83615.1 - 3.5e-27 95.2 36.1 3.9e-26 91.8 34.4 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EAQ83615.1 - 1.4e-11 43.6 10.2 2.1e-11 43.0 10.2 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF4257 PF14074.6 EAQ83615.1 - 0.046 13.9 2.8 9.3 6.5 0.0 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF4257) FAD_binding_4 PF01565.23 EAQ83616.1 - 1.7e-18 66.7 1.8 3.2e-18 65.8 1.8 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EAQ83616.1 - 7.5e-06 26.0 0.0 1.6e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like FAD_binding_3 PF01494.19 EAQ83617.1 - 4.5e-18 65.6 1.6 1.9e-08 34.0 0.2 2.3 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 EAQ83617.1 - 5.8e-05 22.8 3.4 5.8e-05 22.8 3.4 1.9 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EAQ83617.1 - 0.0013 19.0 0.2 0.0013 19.0 0.2 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EAQ83617.1 - 0.0014 18.0 1.7 0.0065 15.7 1.0 1.9 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EAQ83617.1 - 0.015 14.2 1.1 0.29 9.9 0.5 2.2 2 0 0 2 2 2 0 Tryptophan halogenase Pyr_redox PF00070.27 EAQ83617.1 - 0.026 15.1 0.3 0.13 12.8 0.2 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EAQ83617.1 - 0.028 13.5 1.8 0.041 13.0 1.8 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A 3HCDH_N PF02737.18 EAQ83617.1 - 0.029 14.3 0.4 0.048 13.5 0.4 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Tri3 PF07428.11 EAQ83618.1 - 0.00013 21.1 0.0 0.0012 17.8 0.0 1.9 2 0 0 2 2 2 1 15-O-acetyltransferase Tri3 DUF4797 PF16051.5 EAQ83618.1 - 0.15 12.1 0.1 27 4.8 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4797) ADH_zinc_N PF00107.26 EAQ83619.1 - 4.5e-12 46.1 1.4 1.4e-11 44.4 0.1 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EAQ83619.1 - 0.0024 17.7 0.0 0.0047 16.8 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain UCR_Fe-S_N PF10399.9 EAQ83620.1 - 0.29 10.5 2.0 0.53 9.7 2.0 1.4 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Cu-oxidase_3 PF07732.15 EAQ83621.1 - 5.9e-41 139.2 6.2 9.5e-41 138.6 3.3 2.6 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 EAQ83621.1 - 5.7e-31 107.1 12.6 1.3e-30 106.0 0.8 3.1 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 EAQ83621.1 - 2.2e-26 92.8 0.0 5.3e-26 91.6 0.0 1.7 1 0 0 1 1 1 1 Multicopper oxidase ketoacyl-synt PF00109.26 EAQ83623.1 - 7e-34 117.5 0.1 2.1e-24 86.5 0.0 2.7 1 1 1 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EAQ83623.1 - 2.1e-31 108.4 0.0 5.6e-31 107.0 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain HTH_51 PF18558.1 EAQ83623.1 - 4.3e-29 100.2 0.0 1.2e-28 98.8 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain Acyl_transf_1 PF00698.21 EAQ83623.1 - 1.4e-27 97.1 0.1 3.5e-27 95.7 0.1 1.7 1 0 0 1 1 1 1 Acyl transferase domain NAD_binding_4 PF07993.12 EAQ83623.1 - 7.2e-21 74.5 0.0 1.2e-20 73.8 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein SAT PF16073.5 EAQ83623.1 - 5.2e-16 59.1 2.2 8e-10 38.9 0.1 3.4 4 0 0 4 4 3 2 Starter unit:ACP transacylase in aflatoxin biosynthesis Methyltransf_12 PF08242.12 EAQ83623.1 - 1.8e-13 51.0 0.0 4.8e-13 49.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PS-DH PF14765.6 EAQ83623.1 - 7.1e-12 45.2 0.0 1.3e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Methyltransf_25 PF13649.6 EAQ83623.1 - 4.9e-10 40.0 0.0 2.1e-09 37.9 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 EAQ83623.1 - 5.6e-09 36.2 0.1 1.5e-08 34.8 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_23 PF13489.6 EAQ83623.1 - 4.3e-08 33.2 0.0 1.8e-07 31.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EAQ83623.1 - 9.9e-08 32.5 0.0 2.8e-07 31.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAQ83623.1 - 2.1e-07 30.8 0.0 4e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 EAQ83623.1 - 7.6e-05 23.1 0.0 0.00019 21.8 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Ubie_methyltran PF01209.18 EAQ83623.1 - 0.00023 20.6 0.0 0.00073 18.9 0.0 1.8 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Epimerase PF01370.21 EAQ83623.1 - 0.0016 17.9 0.0 0.004 16.7 0.0 1.7 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 EAQ83623.1 - 0.0025 17.8 0.0 0.021 14.7 0.0 2.5 2 0 0 2 2 2 1 KR domain DREV PF05219.12 EAQ83623.1 - 0.065 12.3 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Polysacc_synt_2 PF02719.15 EAQ83623.1 - 0.13 11.3 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 EAQ83623.1 - 0.18 10.9 0.0 5.4 6.0 0.0 2.7 3 0 0 3 3 3 0 RmlD substrate binding domain DapB_N PF01113.20 EAQ83623.1 - 0.2 11.8 0.0 0.49 10.5 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Transferase PF02458.15 EAQ83624.1 - 3.1e-19 68.9 0.0 5.5e-19 68.1 0.0 1.3 1 0 0 1 1 1 1 Transferase family adh_short PF00106.25 EAQ83625.1 - 2e-37 128.6 0.2 2.4e-37 128.3 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EAQ83625.1 - 8e-27 94.3 0.1 1e-26 93.9 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EAQ83625.1 - 8.3e-09 35.6 0.1 3.5e-08 33.6 0.1 1.8 2 0 0 2 2 2 1 KR domain NmrA PF05368.13 EAQ83625.1 - 5.6e-06 26.1 0.0 1e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EAQ83625.1 - 7.4e-06 26.0 0.1 1.4e-05 25.1 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 EAQ83625.1 - 0.017 14.3 0.0 0.024 13.8 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Epimerase PF01370.21 EAQ83625.1 - 0.055 12.9 0.0 0.083 12.3 0.0 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family ADH_N PF08240.12 EAQ83626.1 - 4.9e-06 26.4 0.0 9.8e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EAQ83626.1 - 1.2e-05 25.3 0.5 2.2e-05 24.4 0.5 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase RmlD_sub_bind PF04321.17 EAQ83626.1 - 0.035 13.2 0.2 0.051 12.7 0.2 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain ADH_N_2 PF16884.5 EAQ83626.1 - 0.036 14.0 0.0 0.08 12.8 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase CCER1 PF15482.6 EAQ83629.1 - 0.025 14.5 0.1 0.029 14.3 0.1 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing glutamate-rich protein family 1 VitD-bind_III PF09164.10 EAQ83629.1 - 0.12 12.4 0.1 0.16 12.0 0.1 1.3 1 0 0 1 1 1 0 Vitamin D binding protein, domain III ddrB-ParB PF18763.1 EAQ83629.1 - 0.16 12.0 0.6 0.57 10.3 0.6 1.7 1 1 0 1 1 1 0 ddrB-like ParB superfamily domain DPBB_1 PF03330.18 EAQ83631.1 - 3.5e-10 40.0 0.2 1e-09 38.6 0.2 1.8 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 EAQ83631.1 - 0.011 15.6 0.3 0.017 15.0 0.2 1.4 1 1 0 1 1 1 0 Barwin family Abhydrolase_1 PF00561.20 EAQ83632.1 - 2.7e-23 82.9 0.1 1.2e-21 77.5 0.1 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 EAQ83632.1 - 8.7e-16 57.9 0.0 2.6e-15 56.4 0.0 1.8 2 0 0 2 2 2 1 TAP-like protein DUF3593 PF12159.8 EAQ83634.1 - 0.049 13.7 6.5 0.64 10.1 1.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3593) HTH_Tnp_Tc5 PF03221.16 EAQ83635.1 - 1.5e-07 31.4 0.0 4.3e-07 29.9 0.0 1.8 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.16 EAQ83635.1 - 1.6e-07 30.9 0.0 3.4e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 helix-turn-helix, Psq domain DDE_1 PF03184.19 EAQ83635.1 - 0.0095 15.6 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease SpoIIID PF12116.8 EAQ83635.1 - 0.053 13.6 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Stage III sporulation protein D RVT_1 PF00078.27 EAQ83638.1 - 4e-36 124.6 0.0 6.5e-36 123.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RecC_C PF17946.1 EAQ83638.1 - 0.0039 17.0 5.6 0.28 10.9 0.4 2.4 2 0 0 2 2 2 2 RecC C-terminal domain Glyco_hydro_61 PF03443.14 EAQ83639.1 - 7.9e-62 208.8 1.8 1.1e-61 208.4 1.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 LPMO_10 PF03067.15 EAQ83639.1 - 0.0012 19.5 0.1 0.0029 18.3 0.1 1.7 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading TFIIA PF03153.13 EAQ83639.1 - 0.19 11.7 0.0 0.3 11.0 0.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit AA_permease PF00324.21 EAQ83640.1 - 2.1e-101 339.9 29.9 1e-50 172.7 22.6 2.0 1 1 1 2 2 2 2 Amino acid permease AA_permease_2 PF13520.6 EAQ83640.1 - 1.1e-26 93.7 31.9 2.7e-13 49.5 22.1 2.2 1 1 1 2 2 2 2 Amino acid permease DUF3959 PF13105.6 EAQ83641.1 - 0.0068 15.9 0.6 0.018 14.6 0.6 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3959) Kinesin PF00225.23 EAQ83642.1 - 8.1e-37 126.9 0.0 3.7e-32 111.6 0.0 2.2 1 1 1 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 EAQ83642.1 - 1.6e-05 24.8 0.0 3.4e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding SAM_PNT PF02198.16 EAQ83642.1 - 0.16 11.9 0.0 0.33 10.9 0.0 1.5 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain Amidohydro_3 PF07969.11 EAQ83644.1 - 2.4e-14 53.7 0.3 1.8e-10 40.9 0.0 2.5 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_1 PF01979.20 EAQ83644.1 - 2.8e-10 40.1 0.0 1.9e-09 37.3 0.0 2.0 1 1 0 1 1 1 1 Amidohydrolase family DLH PF01738.18 EAQ83647.1 - 0.00058 19.5 0.2 0.042 13.4 0.0 2.1 1 1 1 2 2 2 2 Dienelactone hydrolase family Esterase PF00756.20 EAQ83647.1 - 0.00062 19.5 0.5 0.0041 16.8 0.5 2.1 1 1 0 1 1 1 1 Putative esterase Esterase_phd PF10503.9 EAQ83647.1 - 0.00087 18.8 0.0 0.0025 17.4 0.0 1.7 1 1 1 2 2 2 1 Esterase PHB depolymerase Abhydrolase_2 PF02230.16 EAQ83647.1 - 0.0011 18.8 0.0 0.0067 16.3 0.0 2.1 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Ecm33 PF12454.8 EAQ83647.1 - 0.012 15.8 0.2 0.033 14.3 0.2 1.7 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein Abhydrolase_1 PF00561.20 EAQ83647.1 - 0.021 14.5 0.0 0.039 13.6 0.0 1.6 1 1 1 2 2 2 0 alpha/beta hydrolase fold zf-XS PF03470.14 EAQ83648.1 - 0.39 11.0 0.2 0.39 11.0 0.2 2.5 2 0 0 2 2 2 0 XS zinc finger domain MFS_1 PF07690.16 EAQ83649.1 - 1.9e-05 23.8 12.5 1.9e-05 23.8 12.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Smim3 PF17307.2 EAQ83649.1 - 0.025 14.1 1.1 0.072 12.6 1.1 1.8 1 0 0 1 1 1 0 Small integral membrane protein 3 Queuosine_synth PF02547.15 EAQ83650.1 - 4.5e-83 279.1 0.0 5e-83 278.9 0.0 1.0 1 0 0 1 1 1 1 Queuosine biosynthesis protein Aminotran_1_2 PF00155.21 EAQ83651.1 - 3.4e-42 144.9 0.0 4.9e-42 144.4 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class I and II PhyH PF05721.13 EAQ83652.1 - 2.3e-18 67.2 0.3 7e-18 65.7 0.1 1.8 2 0 0 2 2 2 1 Phytanoyl-CoA dioxygenase (PhyH) AMP-binding PF00501.28 EAQ83653.1 - 0 1441.3 0.2 6.4e-72 242.5 0.0 9.4 8 1 1 9 9 9 9 AMP-binding enzyme Condensation PF00668.20 EAQ83653.1 - 0 1141.5 0.0 2.7e-43 148.3 0.0 14.1 13 1 1 14 14 14 13 Condensation domain PP-binding PF00550.25 EAQ83653.1 - 2.6e-87 287.1 0.6 1.8e-12 47.4 0.0 8.0 7 0 0 7 7 7 7 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EAQ83653.1 - 3.3e-07 31.2 1.1 0.87 10.6 0.0 6.2 6 0 0 6 6 6 2 AMP-binding enzyme C-terminal domain WES_acyltransf PF03007.16 EAQ83653.1 - 0.013 15.3 0.0 3.5 7.3 0.0 3.9 4 0 0 4 4 4 0 Wax ester synthase-like Acyl-CoA acyltransferase domain Slu7 PF11708.8 EAQ83654.1 - 0.054 13.2 1.4 0.13 12.0 1.4 1.6 1 0 0 1 1 1 0 Pre-mRNA splicing Prp18-interacting factor Glyco_hydro_31 PF01055.26 EAQ83656.1 - 4.8e-150 500.6 3.9 6.3e-150 500.2 3.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 EAQ83656.1 - 4.6e-33 113.9 0.8 8.2e-33 113.1 0.8 1.4 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 EAQ83656.1 - 2.1e-11 44.0 3.5 3.3e-11 43.3 0.9 2.4 2 0 0 2 2 2 1 Galactose mutarotase-like Pec_lyase_C PF00544.19 EAQ83657.1 - 2.1e-38 132.1 5.9 2.8e-38 131.6 5.9 1.2 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 EAQ83657.1 - 0.0029 17.5 7.9 0.038 13.8 7.4 2.2 1 1 0 1 1 1 1 Right handed beta helix region PMI_typeI PF01238.21 EAQ83658.1 - 2e-66 224.7 0.0 2.9e-65 220.9 0.0 2.0 1 1 0 1 1 1 1 Phosphomannose isomerase type I TPR_MalT PF17874.1 EAQ83658.1 - 0.022 14.1 0.2 0.038 13.4 0.2 1.2 1 0 0 1 1 1 0 MalT-like TPR region SF-assemblin PF06705.11 EAQ83658.1 - 0.069 12.5 0.5 0.11 11.8 0.5 1.3 1 0 0 1 1 1 0 SF-assemblin/beta giardin Noelin-1 PF12308.8 EAQ83658.1 - 0.074 13.0 0.1 0.27 11.2 0.0 1.9 2 0 0 2 2 2 0 Neurogenesis glycoprotein Cupin_4 PF08007.12 EAQ83658.1 - 0.14 11.6 0.0 0.29 10.6 0.0 1.5 1 0 0 1 1 1 0 Cupin superfamily protein DUF3292 PF11696.8 EAQ83659.1 - 4.6e-205 682.8 0.3 7.6e-124 414.5 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3292) NAD_binding_1 PF00175.21 EAQ83661.1 - 7.8e-20 71.6 0.0 1.7e-19 70.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 EAQ83661.1 - 1.8e-06 28.2 0.0 0.0026 18.1 0.0 2.3 2 0 0 2 2 2 2 Oxidoreductase FAD-binding domain Bromo_TP PF07524.13 EAQ83661.1 - 0.053 13.5 0.1 0.098 12.7 0.1 1.4 1 0 0 1 1 1 0 Bromodomain associated Oxidored_molyb PF00174.19 EAQ83662.1 - 3.4e-38 131.0 0.0 7.1e-37 126.6 0.0 2.2 1 1 1 2 2 2 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 EAQ83662.1 - 3.2e-10 40.2 0.1 8.1e-10 38.8 0.1 1.7 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Vfa1 PF08432.10 EAQ83662.1 - 1.2 9.5 11.0 1.9 8.8 11.0 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Presenilin PF01080.17 EAQ83662.1 - 5.2 5.7 7.1 7.7 5.2 7.1 1.1 1 0 0 1 1 1 0 Presenilin An_peroxidase PF03098.15 EAQ83663.1 - 1.8e-37 129.1 0.1 2.7e-11 42.7 0.0 4.1 2 1 1 3 3 3 3 Animal haem peroxidase DUF2235 PF09994.9 EAQ83664.1 - 6.2e-103 344.1 0.1 8.5e-103 343.6 0.1 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Palm_thioest PF02089.15 EAQ83664.1 - 0.07 13.0 0.0 0.095 12.5 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase AAA_12 PF13087.6 EAQ83665.1 - 7.5e-33 113.8 0.0 1.3e-32 113.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAQ83665.1 - 8.9e-23 81.4 0.5 2.5e-22 79.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EAQ83665.1 - 2.2e-07 31.3 0.0 2.3e-06 28.0 0.0 2.7 2 1 0 2 2 2 1 AAA domain DUF2075 PF09848.9 EAQ83665.1 - 1.6e-06 27.7 0.0 0.0072 15.6 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) zf-CCCH_4 PF18044.1 EAQ83665.1 - 1.6e-06 27.8 4.3 1.6e-06 27.8 4.3 2.6 2 0 0 2 2 2 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 EAQ83665.1 - 1.6e-06 28.0 5.9 7.1e-06 25.9 5.9 2.3 1 0 0 1 1 1 1 Zinc finger domain AAA_30 PF13604.6 EAQ83665.1 - 0.00086 19.1 0.1 0.0043 16.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 EAQ83665.1 - 0.027 14.5 0.0 0.068 13.2 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit UvrD_C_2 PF13538.6 EAQ83665.1 - 0.082 12.8 0.0 0.24 11.3 0.0 1.9 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Kazal_2 PF07648.15 EAQ83666.1 - 0.0061 16.7 1.3 3.6 7.8 0.0 2.9 3 0 0 3 3 3 2 Kazal-type serine protease inhibitor domain Peptidase_S64 PF08192.11 EAQ83668.1 - 0.004 15.7 0.0 0.0057 15.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family S64 Peptidase_S32 PF05579.13 EAQ83668.1 - 0.065 12.4 0.0 0.074 12.2 0.0 1.1 1 0 0 1 1 1 0 Equine arteritis virus serine endopeptidase S32 Chitin_bind_1 PF00187.19 EAQ83669.1 - 0.00056 20.3 23.5 0.00056 20.3 23.5 4.8 5 0 0 5 5 5 2 Chitin recognition protein TRAM_LAG1_CLN8 PF03798.16 EAQ83670.1 - 3.1e-26 92.3 14.1 3.8e-24 85.5 14.1 2.5 1 1 0 1 1 1 1 TLC domain TRAM1 PF08390.11 EAQ83670.1 - 6.1e-24 83.4 0.2 6.1e-24 83.4 0.2 2.3 2 1 0 2 2 2 1 TRAM1-like protein SLATT_1 PF18181.1 EAQ83670.1 - 0.93 9.4 3.1 4.9 7.1 0.3 2.3 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 Syndecan PF01034.20 EAQ83671.1 - 0.0055 16.6 0.5 0.0093 15.9 0.5 1.2 1 0 0 1 1 1 1 Syndecan domain LPG_synthase_TM PF03706.13 EAQ83671.1 - 0.077 12.5 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 Lysylphosphatidylglycerol synthase TM region SKG6 PF08693.10 EAQ83671.1 - 8.1 5.9 6.6 21 4.6 6.6 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Baculo_PEP_C PF04513.12 EAQ83672.1 - 0.021 14.9 0.3 0.035 14.2 0.3 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus CorA PF01544.18 EAQ83672.1 - 0.089 12.1 0.1 0.13 11.5 0.1 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF1664 PF07889.12 EAQ83672.1 - 0.096 12.7 0.4 0.23 11.5 0.3 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) FPP PF05911.11 EAQ83672.1 - 0.19 9.9 0.1 0.23 9.6 0.1 1.0 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil p450 PF00067.22 EAQ83674.1 - 1.2e-33 116.6 0.0 1.7e-33 116.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 NAD_binding_8 PF13450.6 EAQ83676.1 - 1.2e-13 51.1 0.0 1.2e-13 51.1 0.0 2.1 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EAQ83676.1 - 8.1e-05 21.9 1.0 0.00013 21.1 1.0 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 EAQ83676.1 - 0.00012 21.6 0.2 0.00019 21.0 0.2 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 EAQ83676.1 - 0.00013 21.4 0.0 0.00025 20.5 0.0 1.5 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase HI0933_like PF03486.14 EAQ83676.1 - 0.0002 20.2 0.4 0.0003 19.6 0.4 1.2 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.24 EAQ83676.1 - 0.00048 19.8 0.5 0.001 18.7 0.5 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EAQ83676.1 - 0.0043 16.3 0.1 0.0074 15.6 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EAQ83676.1 - 0.01 15.8 0.1 0.031 14.3 0.1 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding DUF4148 PF13663.6 EAQ83676.1 - 0.012 15.8 1.0 0.12 12.5 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) Thi4 PF01946.17 EAQ83676.1 - 0.022 14.0 0.2 0.036 13.3 0.2 1.2 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.14 EAQ83676.1 - 0.052 12.4 0.2 0.086 11.7 0.2 1.3 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox_3 PF13738.6 EAQ83676.1 - 0.065 12.5 0.0 0.096 11.9 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EAQ83676.1 - 0.11 13.0 0.1 0.24 12.0 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Caf4 PF11615.8 EAQ83678.1 - 0.15 12.1 0.0 0.4 10.7 0.0 1.7 1 0 0 1 1 1 0 CCR4-associated factor 4 PHO4 PF01384.20 EAQ83679.1 - 5.6e-41 140.7 4.7 2.6e-14 53.0 7.8 3.4 2 1 1 3 3 3 3 Phosphate transporter family Peptidase_S8 PF00082.22 EAQ83682.1 - 7.5e-33 114.1 12.0 1.6e-32 113.0 12.0 1.5 1 0 0 1 1 1 1 Subtilase family Oxidored_FMN PF00724.20 EAQ83684.1 - 1e-60 205.8 0.0 1.2e-60 205.6 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.17 EAQ83684.1 - 0.024 13.7 0.1 0.22 10.6 0.0 2.1 1 1 0 2 2 2 0 Dihydrouridine synthase (Dus) DUF4407 PF14362.6 EAQ83685.1 - 0.0029 17.0 3.5 0.0037 16.6 3.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) eIF-3_zeta PF05091.12 EAQ83685.1 - 0.013 14.5 2.1 0.012 14.7 2.1 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Presenilin PF01080.17 EAQ83685.1 - 0.032 13.0 0.8 0.029 13.2 0.8 1.1 1 0 0 1 1 1 0 Presenilin Peptidase_S49_N PF08496.10 EAQ83685.1 - 0.063 13.3 2.4 0.12 12.5 2.4 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Med15 PF09606.10 EAQ83685.1 - 0.069 11.8 22.4 0.079 11.6 22.4 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4834 PF16118.5 EAQ83685.1 - 0.083 13.9 5.3 0.14 13.2 5.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Neur_chan_memb PF02932.16 EAQ83685.1 - 0.27 11.3 0.3 0.23 11.5 0.3 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region EMC3_TMCO1 PF01956.16 EAQ83685.1 - 1.7 8.3 4.0 2.4 7.8 4.0 1.1 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like SpoIIP PF07454.11 EAQ83685.1 - 2.4 7.6 8.1 3.1 7.2 8.1 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Coilin_N PF15862.5 EAQ83685.1 - 2.6 7.9 8.1 4.8 7.0 8.1 1.4 1 0 0 1 1 1 0 Coilin N-terminus TERB2 PF15101.6 EAQ83685.1 - 3.5 7.6 10.7 5.1 7.1 10.7 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Pex14_N PF04695.13 EAQ83685.1 - 3.9 8.1 15.4 9.6 6.8 15.8 1.4 2 0 0 2 2 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2722 PF10846.8 EAQ83685.1 - 4.6 6.1 25.3 6.1 5.7 25.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) ANAPC_CDC26 PF10471.9 EAQ83685.1 - 5.3 7.9 26.6 1.8 9.5 24.0 1.6 2 0 0 2 2 1 0 Anaphase-promoting complex APC subunit CDC26 Spt20 PF12090.8 EAQ83685.1 - 7.9 6.0 30.2 11 5.6 30.2 1.1 1 0 0 1 1 1 0 Spt20 family Baculo_PP31 PF05311.11 EAQ83685.1 - 8.2 5.8 7.9 11 5.4 7.9 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Pyr_redox_3 PF13738.6 EAQ83686.1 - 5.5e-13 48.8 0.1 7.5e-05 22.1 0.0 3.2 3 0 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EAQ83686.1 - 8.2e-11 41.7 0.2 0.014 14.7 0.0 3.1 3 0 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 EAQ83686.1 - 6e-07 28.3 0.7 0.4 9.0 0.0 3.4 3 1 0 3 3 3 3 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 EAQ83686.1 - 2.3e-05 24.5 0.0 0.00047 20.3 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EAQ83686.1 - 2.3e-05 24.9 0.1 0.49 11.0 0.0 3.4 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EAQ83686.1 - 2.6e-05 23.6 0.0 6.3e-05 22.4 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain K_oxygenase PF13434.6 EAQ83686.1 - 8.1e-05 21.9 0.1 0.14 11.3 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 EAQ83686.1 - 0.00036 19.4 0.3 0.0022 16.8 0.2 2.0 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 EAQ83686.1 - 0.0055 15.8 0.7 0.062 12.4 0.1 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 EAQ83686.1 - 0.014 14.7 0.0 0.022 14.1 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 EAQ83686.1 - 0.024 13.9 0.0 0.041 13.2 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 EAQ83686.1 - 0.024 14.7 0.2 3.8 7.6 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.24 EAQ83686.1 - 0.028 13.5 0.2 0.044 12.9 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 EAQ83686.1 - 0.029 13.6 0.0 0.11 11.7 0.0 1.9 2 0 0 2 2 2 0 Thi4 family NAD_binding_9 PF13454.6 EAQ83686.1 - 0.03 14.3 0.0 2.8 7.9 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding TrkA_N PF02254.18 EAQ83686.1 - 0.034 14.4 0.1 0.58 10.4 0.0 2.6 3 0 0 3 3 3 0 TrkA-N domain DUF498 PF04430.14 EAQ83686.1 - 0.12 12.4 0.0 0.3 11.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF498/DUF598) ketoacyl-synt PF00109.26 EAQ83688.1 - 1.4e-76 257.4 0.0 2.8e-76 256.5 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.6 EAQ83688.1 - 6.8e-46 156.9 0.0 1.7e-45 155.6 0.0 1.7 2 0 0 2 2 2 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 EAQ83688.1 - 1.7e-43 149.4 0.0 3.2e-43 148.4 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 EAQ83688.1 - 2.4e-36 125.3 0.0 7.9e-36 123.6 0.0 1.9 1 0 0 1 1 1 1 KR domain Ketoacyl-synt_C PF02801.22 EAQ83688.1 - 1.4e-35 121.8 0.0 3.1e-35 120.7 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 EAQ83688.1 - 3.8e-09 37.0 0.0 9.6e-09 35.7 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension PP-binding PF00550.25 EAQ83688.1 - 0.00064 20.0 0.0 0.0017 18.7 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.25 EAQ83688.1 - 0.0011 18.4 0.0 0.0039 16.7 0.0 1.9 1 0 0 1 1 1 1 short chain dehydrogenase Thiolase_N PF00108.23 EAQ83688.1 - 0.018 14.4 0.0 0.043 13.2 0.0 1.5 1 0 0 1 1 1 0 Thiolase, N-terminal domain Globin PF00042.22 EAQ83690.1 - 7.9e-08 32.8 0.0 1.2e-07 32.2 0.0 1.3 1 0 0 1 1 1 1 Globin NAD_binding_1 PF00175.21 EAQ83690.1 - 4.4e-05 24.1 0.0 7.7e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Protoglobin PF11563.8 EAQ83690.1 - 5.4e-05 23.1 0.1 0.00012 22.0 0.1 1.6 1 1 0 1 1 1 1 Protoglobin Thymidylat_synt PF00303.19 EAQ83692.1 - 1.1e-106 355.9 0.0 1.3e-106 355.7 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase Glycos_transf_1 PF00534.20 EAQ83693.1 - 4.1e-22 78.5 0.0 1.8e-21 76.4 0.0 2.0 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EAQ83693.1 - 8.2e-14 52.2 0.0 1.5e-13 51.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 EAQ83693.1 - 0.0024 18.2 0.0 0.0087 16.4 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 Sod_Fe_N PF00081.22 EAQ83694.1 - 1.7e-30 105.3 0.7 2.2e-30 105.0 0.7 1.2 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Sod_Fe_C PF02777.18 EAQ83694.1 - 0.00055 20.1 0.1 0.001 19.2 0.1 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sld5 PF05916.11 EAQ83695.1 - 7.3e-17 61.8 0.0 1.3e-16 61.0 0.0 1.6 1 1 1 2 2 2 1 GINS complex protein BATS PF06968.13 EAQ83696.1 - 5.9e-24 84.0 1.9 1.4e-23 82.9 0.1 2.5 3 1 0 3 3 3 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 EAQ83696.1 - 1.2e-15 58.3 0.1 3e-15 57.0 0.1 1.7 1 0 0 1 1 1 1 Radical SAM superfamily DUF3405 PF11885.8 EAQ83698.1 - 3.4e-141 471.4 3.6 4.4e-141 471.0 3.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) Helicase_C PF00271.31 EAQ83699.1 - 1e-06 29.0 0.1 3.7e-06 27.3 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 EAQ83699.1 - 0.0062 16.3 0.0 0.017 14.9 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Neur PF00064.18 EAQ83699.1 - 0.11 11.2 0.1 0.18 10.6 0.1 1.2 1 0 0 1 1 1 0 Neuraminidase ResIII PF04851.15 EAQ83699.1 - 0.16 11.9 0.0 0.88 9.5 0.0 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit HTH_38 PF13936.6 EAQ83700.1 - 0.062 13.1 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain CDC48_2 PF02933.17 EAQ83700.1 - 0.098 12.5 0.1 0.35 10.7 0.0 2.0 2 0 0 2 2 2 0 Cell division protein 48 (CDC48), domain 2 Nop14 PF04147.12 EAQ83700.1 - 0.73 8.0 4.3 0.83 7.8 4.3 1.2 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 EAQ83700.1 - 3.5 5.6 9.9 4.9 5.1 9.9 1.3 1 0 0 1 1 1 0 DNA polymerase phi Aldose_epim PF01263.20 EAQ83702.1 - 6.9e-55 186.5 0.2 8e-55 186.3 0.2 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase FA_hydroxylase PF04116.13 EAQ83703.1 - 5.9e-25 88.1 23.9 1.7e-24 86.7 22.0 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF4727 PF15856.5 EAQ83703.1 - 0.23 11.0 1.7 0.26 10.8 0.8 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4727) Ank_4 PF13637.6 EAQ83704.1 - 2e-17 63.3 0.1 0.00027 21.4 0.0 5.2 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAQ83704.1 - 3e-14 53.3 0.0 6.8e-12 45.8 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAQ83704.1 - 1.5e-12 47.5 0.2 7e-07 29.4 0.0 3.6 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 EAQ83704.1 - 1.3e-10 41.2 0.5 2.8e-05 24.3 0.1 4.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 EAQ83704.1 - 2.8e-08 33.4 0.2 0.0068 16.8 0.1 5.0 5 0 0 5 5 3 1 Ankyrin repeat NACHT PF05729.12 EAQ83704.1 - 1.1e-06 28.6 0.0 7.2e-06 26.0 0.0 2.2 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 EAQ83704.1 - 2.5e-05 24.7 0.0 0.00016 22.1 0.0 2.4 2 0 0 2 2 1 1 AAA ATPase domain DUF676 PF05057.14 EAQ83704.1 - 0.00015 21.3 0.0 0.00044 19.8 0.0 1.7 2 0 0 2 2 2 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 EAQ83704.1 - 0.0016 18.2 0.0 0.0042 16.8 0.0 1.7 2 0 0 2 2 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 EAQ83704.1 - 0.0033 18.1 0.3 0.038 14.6 0.3 2.7 2 1 0 2 2 2 1 Alpha/beta hydrolase family AAA PF00004.29 EAQ83704.1 - 0.0033 17.8 0.0 0.013 15.9 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) KAP_NTPase PF07693.14 EAQ83704.1 - 0.0036 16.6 0.2 0.03 13.6 0.0 2.1 2 0 0 2 2 2 1 KAP family P-loop domain LCAT PF02450.15 EAQ83704.1 - 0.0068 15.6 0.0 0.011 14.9 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase AAA_22 PF13401.6 EAQ83704.1 - 0.0099 16.2 0.0 0.066 13.5 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EAQ83704.1 - 0.014 15.2 0.1 0.055 13.2 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain Ploopntkinase3 PF18751.1 EAQ83704.1 - 0.039 13.9 0.0 0.094 12.6 0.0 1.6 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 NB-ARC PF00931.22 EAQ83704.1 - 0.047 12.9 0.0 0.51 9.5 0.0 2.5 3 0 0 3 3 3 0 NB-ARC domain RNA_helicase PF00910.22 EAQ83704.1 - 0.052 13.9 0.1 0.38 11.2 0.0 2.5 3 0 0 3 3 3 0 RNA helicase Viral_helicase1 PF01443.18 EAQ83704.1 - 0.17 11.6 0.0 0.36 10.5 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Palm_thioest PF02089.15 EAQ83704.1 - 0.17 11.7 0.0 0.34 10.7 0.0 1.4 1 0 0 1 1 1 0 Palmitoyl protein thioesterase DUF900 PF05990.12 EAQ83704.1 - 0.19 11.2 0.0 0.41 10.1 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) UBM PF14377.6 EAQ83705.1 - 0.0036 16.7 0.9 0.0094 15.4 0.9 1.7 1 0 0 1 1 1 1 Ubiquitin binding region MoeA_N PF03453.17 EAQ83705.1 - 0.0057 16.4 3.2 0.0095 15.7 3.2 1.3 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) AAA PF00004.29 EAQ83706.1 - 2.4e-06 28.0 0.0 5.1e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_6 PF17866.1 EAQ83706.1 - 2.1e-05 24.6 0.2 0.00019 21.5 0.0 2.4 2 0 0 2 2 2 1 AAA lid domain Dicty_REP PF05086.12 EAQ83706.1 - 2.4 6.0 7.5 3.7 5.4 7.5 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF4141 PF13605.6 EAQ83707.1 - 0.11 11.8 0.5 0.71 9.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4141) COesterase PF00135.28 EAQ83708.1 - 3.3e-78 263.8 0.0 4.7e-78 263.3 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EAQ83708.1 - 1.4e-07 31.6 0.1 7.2e-07 29.3 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EAQ83708.1 - 0.00034 20.2 0.2 0.00056 19.4 0.2 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family FA_desaturase PF00487.24 EAQ83709.1 - 5.6e-33 114.9 21.6 7.8e-33 114.4 21.6 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 EAQ83709.1 - 9e-10 38.6 0.0 2.6e-09 37.1 0.0 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF3821 PF12863.7 EAQ83709.1 - 0.026 14.4 0.4 0.059 13.3 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3821) DUF3638 PF12340.8 EAQ83711.1 - 2.1e-91 305.3 0.1 3.8e-91 304.4 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.8 EAQ83711.1 - 8.6e-18 63.4 1.2 1.8e-17 62.4 1.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) Dicty_CAR PF05462.11 EAQ83712.1 - 3.2e-13 49.5 6.2 3.2e-13 49.5 6.2 1.5 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor Git3 PF11710.8 EAQ83712.1 - 2.8e-10 40.3 9.5 2.8e-10 40.3 9.5 1.6 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.21 EAQ83712.1 - 3.6e-07 29.8 6.2 5e-07 29.3 6.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) IRF-2BP1_2 PF11261.8 EAQ83713.1 - 0.12 11.9 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Interferon regulatory factor 2-binding protein zinc finger Glyco_hydro_36 PF17167.4 EAQ83715.1 - 1.2e-58 198.8 0.0 2.6e-58 197.7 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase 36 superfamily, catalytic domain Glyco_transf_36 PF06165.11 EAQ83715.1 - 6.8e-28 97.7 0.0 1.1e-27 97.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 36 Bac_rhamnosid6H PF17389.2 EAQ83715.1 - 0.023 14.0 0.0 0.05 12.9 0.0 1.5 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain MULE PF10551.9 EAQ83716.1 - 4e-25 88.0 0.0 7e-25 87.3 0.0 1.4 1 0 0 1 1 1 1 MULE transposase domain Esterase_phd PF10503.9 EAQ83718.1 - 1.4e-23 83.5 1.5 2.8e-23 82.6 1.5 1.4 1 0 0 1 1 1 1 Esterase PHB depolymerase CBM_1 PF00734.18 EAQ83718.1 - 5.5e-09 35.8 7.0 1.6e-08 34.3 7.0 1.9 1 0 0 1 1 1 1 Fungal cellulose binding domain Peptidase_S9 PF00326.21 EAQ83718.1 - 4.5e-08 32.8 0.4 1.1e-07 31.5 0.4 1.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 EAQ83718.1 - 0.0031 17.4 0.1 0.0052 16.7 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EAQ83718.1 - 0.2 10.9 0.1 5.2 6.3 0.1 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Zn_clus PF00172.18 EAQ83722.1 - 1.2e-07 31.7 12.7 1.7e-07 31.3 12.7 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_25 PF13649.6 EAQ83723.1 - 1.9e-13 50.9 0.0 7.5e-13 49.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EAQ83723.1 - 2.3e-11 44.2 0.0 2e-10 41.2 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EAQ83723.1 - 2.9e-09 37.0 0.0 4.7e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EAQ83723.1 - 6.5e-08 33.2 0.0 1.7e-07 31.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAQ83723.1 - 2.7e-07 30.5 0.0 4.7e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EAQ83723.1 - 0.00078 19.0 0.0 0.0017 17.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.18 EAQ83723.1 - 0.056 12.7 0.0 0.088 12.1 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain FtsJ PF01728.19 EAQ83723.1 - 0.13 12.4 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_32 PF13679.6 EAQ83723.1 - 0.28 11.2 0.0 0.48 10.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain ketoacyl-synt PF00109.26 EAQ83724.1 - 6.7e-63 212.6 0.0 2.1e-62 211.0 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EAQ83724.1 - 4.4e-37 126.7 0.1 1.1e-36 125.4 0.1 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain HTH_51 PF18558.1 EAQ83724.1 - 1.3e-29 101.9 0.0 1e-28 99.0 0.0 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain PS-DH PF14765.6 EAQ83724.1 - 1.3e-19 70.6 0.0 3e-19 69.4 0.0 1.6 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 EAQ83724.1 - 2.3e-19 70.1 0.5 5.4e-19 68.8 0.5 1.6 1 0 0 1 1 1 1 Acyl transferase domain PP-binding PF00550.25 EAQ83724.1 - 1.1e-17 64.1 4.4 6.2e-10 39.3 0.6 2.6 2 0 0 2 2 2 2 Phosphopantetheine attachment site Abhydrolase_3 PF07859.13 EAQ83724.1 - 2e-12 47.4 0.0 1.5e-11 44.6 0.0 2.3 2 0 0 2 2 2 1 alpha/beta hydrolase fold Methyltransf_12 PF08242.12 EAQ83724.1 - 8.5e-12 45.7 0.0 4.7e-11 43.3 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Peptidase_S9 PF00326.21 EAQ83724.1 - 2e-09 37.3 0.0 1.3e-06 28.1 0.0 2.8 3 0 0 3 3 3 2 Prolyl oligopeptidase family SAT PF16073.5 EAQ83724.1 - 1.6e-08 34.6 4.5 3.1e-07 30.4 0.0 3.7 3 1 0 3 3 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis KAsynt_C_assoc PF16197.5 EAQ83724.1 - 1.7e-08 34.9 0.0 6.5e-07 29.8 0.0 2.8 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension Methyltransf_25 PF13649.6 EAQ83724.1 - 8e-08 32.9 0.0 7.3e-07 29.8 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAQ83724.1 - 0.0046 16.8 0.0 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Peripla_BP_1 PF00532.21 EAQ83724.1 - 0.008 15.6 0.1 0.023 14.2 0.0 1.7 2 0 0 2 2 2 1 Periplasmic binding proteins and sugar binding domain of LacI family Methyltransf_16 PF10294.9 EAQ83724.1 - 0.0085 15.9 0.0 0.033 13.9 0.0 1.9 2 0 0 2 2 2 1 Lysine methyltransferase Methyltransf_33 PF10017.9 EAQ83724.1 - 0.0085 15.3 0.0 0.016 14.3 0.0 1.4 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent DLH PF01738.18 EAQ83724.1 - 0.018 14.6 0.0 0.46 10.0 0.0 2.6 2 0 0 2 2 2 0 Dienelactone hydrolase family Methyltransf_11 PF08241.12 EAQ83724.1 - 0.033 14.9 0.0 0.18 12.5 0.0 2.4 2 0 0 2 2 1 0 Methyltransferase domain Abhydrolase_2 PF02230.16 EAQ83724.1 - 0.098 12.4 0.0 4.6 7.0 0.0 2.6 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase COesterase PF00135.28 EAQ83724.1 - 0.14 11.0 0.0 0.24 10.2 0.0 1.3 1 0 0 1 1 1 0 Carboxylesterase family Abhydrolase_6 PF12697.7 EAQ83724.1 - 0.25 11.9 12.6 0.035 14.7 5.3 3.1 3 0 0 3 3 3 0 Alpha/beta hydrolase family FAD_binding_3 PF01494.19 EAQ83725.1 - 1.4e-63 215.2 0.0 5.3e-61 206.8 0.0 2.1 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EAQ83725.1 - 3.1e-05 23.4 0.0 0.0048 16.2 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Phe_hydrox_dim PF07976.12 EAQ83725.1 - 0.0011 19.0 0.0 0.002 18.2 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain DAO PF01266.24 EAQ83725.1 - 0.017 14.7 0.1 0.79 9.2 0.0 3.0 3 1 0 4 4 4 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EAQ83725.1 - 0.023 14.0 0.1 0.042 13.1 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EAQ83725.1 - 0.068 12.2 0.0 1.7 7.7 0.1 2.3 3 0 0 3 3 3 0 FAD binding domain NAD_binding_8 PF13450.6 EAQ83725.1 - 0.085 13.1 0.2 0.5 10.6 0.0 2.4 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EAQ83725.1 - 0.12 11.6 0.0 0.24 10.6 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Myb_DNA-binding PF00249.31 EAQ83727.1 - 1.8e-19 69.7 1.3 1.4e-09 38.0 0.1 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAQ83727.1 - 8.1e-11 42.0 0.7 0.00046 20.4 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAQ83727.1 - 0.0028 17.5 0.0 0.038 13.9 0.0 2.2 1 1 1 2 2 2 1 Myb DNA-binding like Epimerase PF01370.21 EAQ83728.1 - 5.5e-10 39.1 0.0 2.5e-09 37.0 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EAQ83728.1 - 3e-05 24.0 1.1 5.5e-05 23.1 0.3 1.8 2 0 0 2 2 2 1 NAD(P)H-binding KR PF08659.10 EAQ83728.1 - 0.00053 19.9 1.0 0.00053 19.9 1.0 1.5 2 0 0 2 2 2 1 KR domain NmrA PF05368.13 EAQ83728.1 - 0.00078 19.1 0.1 0.0024 17.5 0.6 1.5 2 0 0 2 2 2 1 NmrA-like family CbiJ PF02571.14 EAQ83728.1 - 0.0047 16.4 1.2 0.0073 15.8 1.2 1.3 1 0 0 1 1 1 1 Precorrin-6x reductase CbiJ/CobK 3Beta_HSD PF01073.19 EAQ83728.1 - 0.013 14.5 0.0 0.17 10.8 0.0 2.1 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EAQ83728.1 - 0.019 14.4 0.0 0.21 11.0 0.0 2.3 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase TrkA_N PF02254.18 EAQ83728.1 - 0.025 14.8 0.2 0.042 14.1 0.2 1.4 1 0 0 1 1 1 0 TrkA-N domain p450 PF00067.22 EAQ83729.1 - 2e-62 211.5 0.0 2.6e-62 211.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 EAQ83730.1 - 3.1e-25 88.9 41.9 3.1e-25 88.9 41.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily NAD_binding_4 PF07993.12 EAQ83731.1 - 1.1e-28 100.1 0.0 1.5e-28 99.7 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 EAQ83731.1 - 1.5e-11 43.5 0.0 2.8e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 EAQ83731.1 - 9.5e-10 38.3 0.0 2.5e-09 37.0 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 EAQ83731.1 - 7.7e-06 26.2 0.0 2e-05 24.9 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site PilX PF13681.6 EAQ83731.1 - 0.12 12.7 0.0 0.25 11.8 0.0 1.5 1 0 0 1 1 1 0 Type IV pilus assembly protein PilX C-term KR PF08659.10 EAQ83731.1 - 0.13 12.2 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 KR domain CBM_1 PF00734.18 EAQ83733.1 - 5.9e-13 48.5 10.9 5.9e-13 48.5 10.9 2.6 3 0 0 3 3 3 1 Fungal cellulose binding domain Lipase_GDSL_2 PF13472.6 EAQ83733.1 - 8.9e-09 36.0 0.2 1.4e-08 35.3 0.2 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EAQ83733.1 - 4.1e-06 26.9 0.1 5e-06 26.6 0.1 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase MGC-24 PF05283.11 EAQ83733.1 - 5.3 7.5 12.0 0.099 13.1 4.5 1.9 2 1 1 3 3 3 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin RGS PF00615.19 EAQ83734.1 - 2.8e-07 30.8 0.0 1.1e-05 25.7 0.0 2.1 2 0 0 2 2 2 2 Regulator of G protein signaling domain PH_10 PF15411.6 EAQ83740.1 - 1.6e-40 138.2 0.1 3.2e-40 137.2 0.1 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain CDC24 PF06395.11 EAQ83740.1 - 4.4e-33 113.4 0.0 9.1e-33 112.4 0.0 1.6 1 0 0 1 1 1 1 CDC24 Calponin RhoGEF PF00621.20 EAQ83740.1 - 3.5e-29 102.3 0.0 6.3e-29 101.5 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain PB1 PF00564.24 EAQ83740.1 - 2.5e-08 33.7 0.0 5.3e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 PB1 domain WD40 PF00400.32 EAQ83741.1 - 6.8e-28 96.3 10.8 3.6e-05 24.4 0.0 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAQ83741.1 - 7.8e-08 32.5 0.2 0.59 10.5 0.0 3.6 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EAQ83741.1 - 0.0024 16.6 0.7 0.13 10.9 0.1 2.4 2 1 0 2 2 2 2 Nucleoporin Nup120/160 WD40_like PF17005.5 EAQ83741.1 - 0.0026 17.2 0.1 0.045 13.1 0.0 2.4 2 1 0 2 2 2 1 WD40-like domain MgtE_N PF03448.17 EAQ83741.1 - 0.17 12.5 0.0 0.36 11.5 0.0 1.5 1 0 0 1 1 1 0 MgtE intracellular N domain F-box-like PF12937.7 EAQ83741.1 - 0.3 11.0 1.5 2.4 8.1 0.2 2.6 2 0 0 2 2 2 0 F-box-like Snf7 PF03357.21 EAQ83742.1 - 1e-43 148.9 11.8 1.2e-43 148.7 11.8 1.1 1 0 0 1 1 1 1 Snf7 NPV_P10 PF05531.12 EAQ83742.1 - 0.0084 16.5 8.5 1.7 9.1 0.0 3.4 2 1 0 2 2 2 1 Nucleopolyhedrovirus P10 protein Alpha-2-MRAP_C PF06401.11 EAQ83742.1 - 0.011 15.7 2.7 0.011 15.7 2.7 1.8 1 1 0 1 1 1 0 Alpha-2-macroglobulin RAP, C-terminal domain Seryl_tRNA_N PF02403.22 EAQ83742.1 - 0.037 14.2 12.5 0.46 10.7 2.4 2.9 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain BBS2_C PF14782.6 EAQ83742.1 - 0.048 12.4 3.3 0.065 12.0 3.3 1.2 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal DUF4201 PF13870.6 EAQ83742.1 - 0.061 13.0 8.8 0.086 12.6 7.9 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) XhlA PF10779.9 EAQ83742.1 - 0.089 13.0 11.9 1.6 9.0 2.3 3.8 2 1 3 5 5 5 0 Haemolysin XhlA CENP-F_leu_zip PF10473.9 EAQ83742.1 - 0.14 12.1 9.6 5.7 7.0 7.6 2.9 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF150 PF02576.17 EAQ83742.1 - 0.18 12.3 1.0 0.53 10.7 1.0 1.9 1 1 0 1 1 1 0 RimP N-terminal domain FlaC_arch PF05377.11 EAQ83742.1 - 0.19 12.2 8.4 3.1 8.3 0.0 3.8 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) Mod_r PF07200.13 EAQ83742.1 - 0.23 11.6 10.9 0.35 11.0 6.8 2.3 1 1 2 3 3 3 0 Modifier of rudimentary (Mod(r)) protein FlxA PF14282.6 EAQ83742.1 - 0.28 11.2 13.6 0.24 11.4 11.7 1.8 1 1 1 2 2 2 0 FlxA-like protein FUSC PF04632.12 EAQ83742.1 - 0.33 9.5 4.3 0.86 8.1 1.0 1.9 1 1 1 2 2 2 0 Fusaric acid resistance protein family Prominin PF05478.11 EAQ83742.1 - 0.39 8.6 4.0 0.52 8.2 4.0 1.3 1 0 0 1 1 1 0 Prominin COG2 PF06148.11 EAQ83742.1 - 0.42 10.7 6.1 0.25 11.4 3.0 2.1 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 SKA1 PF07160.12 EAQ83742.1 - 0.68 9.7 7.6 1.7 8.4 6.3 2.0 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 DUF4446 PF14584.6 EAQ83742.1 - 2.5 8.1 5.9 7.9 6.4 1.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) Atg14 PF10186.9 EAQ83742.1 - 3.7 6.6 9.2 10 5.1 8.9 1.6 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF2205 PF10224.9 EAQ83742.1 - 4.7 7.3 10.7 5.7 7.0 4.0 3.2 1 1 1 3 3 3 0 Short coiled-coil protein NmrA PF05368.13 EAQ83743.1 - 3.2e-24 85.8 0.0 3.9e-24 85.5 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EAQ83743.1 - 3.4e-14 53.1 0.0 4.3e-14 52.8 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EAQ83743.1 - 0.0035 16.9 0.0 0.011 15.2 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EAQ83743.1 - 0.19 11.1 0.0 0.25 10.7 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Beta-lactamase PF00144.24 EAQ83745.1 - 6.2e-44 150.6 0.6 9.1e-44 150.0 0.6 1.2 1 0 0 1 1 1 1 Beta-lactamase Hormone_1 PF00103.20 EAQ83746.1 - 0.059 13.1 0.1 0.13 12.0 0.1 1.5 1 0 0 1 1 1 0 Somatotropin hormone family Dimer_Tnp_hAT PF05699.14 EAQ83747.1 - 3e-15 55.8 0.1 6.5e-15 54.7 0.1 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region CDC45 PF02724.14 EAQ83757.1 - 4.4 5.5 6.3 7 4.8 6.3 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 EAQ83757.1 - 6.2 4.9 5.9 11 4.1 5.9 1.3 1 0 0 1 1 1 0 Nop14-like family RabGAP-TBC PF00566.18 EAQ83758.1 - 1.8e-48 165.1 0.0 7.3e-47 159.8 0.0 2.5 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Cnn_1N PF07989.11 EAQ83758.1 - 0.00016 21.7 16.3 0.0099 16.0 11.8 3.7 1 1 1 2 2 2 2 Centrosomin N-terminal motif 1 HALZ PF02183.18 EAQ83758.1 - 0.0082 16.3 0.3 0.0082 16.3 0.3 4.4 5 0 0 5 5 5 2 Homeobox associated leucine zipper Jnk-SapK_ap_N PF09744.9 EAQ83758.1 - 0.0091 16.2 18.2 0.0091 16.2 18.2 4.0 4 2 1 5 5 5 1 JNK_SAPK-associated protein-1 KASH_CCD PF14662.6 EAQ83758.1 - 0.086 12.7 24.4 0.24 11.2 9.1 2.8 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH DUF4094 PF13334.6 EAQ83758.1 - 2.3 8.7 11.5 0.19 12.1 4.3 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4094) Ribosomal_S8e PF01201.22 EAQ83759.1 - 9.5e-56 187.8 0.9 1.1e-55 187.5 0.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e DUF913 PF06025.12 EAQ83760.1 - 6.3e-122 407.1 0.0 6.3e-122 407.1 0.0 6.6 6 1 0 6 6 6 1 Domain of Unknown Function (DUF913) DUF908 PF06012.12 EAQ83760.1 - 1.2e-118 396.6 0.0 1.2e-118 396.6 0.0 5.1 6 1 0 6 6 6 1 Domain of Unknown Function (DUF908) HECT PF00632.25 EAQ83760.1 - 2.9e-76 256.9 0.8 5.3e-60 203.5 0.1 3.5 4 0 0 4 4 4 2 HECT-domain (ubiquitin-transferase) UBM PF14377.6 EAQ83760.1 - 4.3e-25 86.4 15.5 2.8e-08 32.9 0.1 4.0 3 0 0 3 3 3 3 Ubiquitin binding region Ribosomal_S6e PF01092.19 EAQ83761.1 - 1.5e-55 186.6 0.1 2.9e-55 185.6 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein S6e Atg14 PF10186.9 EAQ83761.1 - 0.19 10.8 9.0 0.24 10.4 9.0 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Diphthamide_syn PF01866.17 EAQ83762.1 - 1.2e-111 373.0 0.0 1.5e-111 372.7 0.0 1.0 1 0 0 1 1 1 1 Putative diphthamide synthesis protein Ctf8 PF09696.10 EAQ83763.1 - 1.1e-29 103.5 0.0 1.6e-29 103.1 0.0 1.2 1 0 0 1 1 1 1 Ctf8 Aldose_epim PF01263.20 EAQ83764.1 - 2.3e-49 168.3 0.1 3.5e-49 167.7 0.1 1.2 1 0 0 1 1 1 1 Aldose 1-epimerase PGPGW PF09656.10 EAQ83764.1 - 0.038 13.5 0.7 0.067 12.7 0.7 1.3 1 0 0 1 1 1 0 Putative transmembrane protein (PGPGW) ATP-synt_ab PF00006.25 EAQ83765.1 - 1.7e-41 142.3 0.0 1.1e-25 90.5 0.0 2.2 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain DUF5535 PF17687.1 EAQ83765.1 - 0.17 12.1 0.0 0.31 11.2 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5535) Pro_isomerase PF00160.21 EAQ83766.1 - 9.5e-41 139.7 0.0 1.7e-40 138.8 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Succ_DH_flav_C PF02910.20 EAQ83766.1 - 0.0082 16.1 0.1 0.019 14.9 0.1 1.6 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term HSF_DNA-bind PF00447.17 EAQ83767.1 - 3.3e-28 98.2 0.3 6.8e-28 97.1 0.3 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding Ets PF00178.22 EAQ83767.1 - 0.053 14.0 0.0 0.13 12.7 0.0 1.6 1 0 0 1 1 1 0 Ets-domain Pro_isomerase PF00160.21 EAQ83768.1 - 1.5e-44 152.1 0.0 1.7e-44 151.9 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Arrestin_C PF02752.22 EAQ83769.1 - 1.1e-12 48.6 0.0 5.8e-11 43.0 0.0 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain tRNA_int_end_N2 PF12928.7 EAQ83770.1 - 1.8e-18 66.5 0.7 3.2e-18 65.7 0.7 1.4 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.14 EAQ83770.1 - 0.091 12.4 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 tRNA intron endonuclease, N-terminal domain K_channel_TID PF07941.11 EAQ83771.1 - 0.51 10.8 11.7 0.21 12.1 7.9 2.3 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain zf-ZPR1 PF03367.13 EAQ83772.1 - 2e-112 372.3 0.1 1.7e-58 197.0 0.2 2.1 2 0 0 2 2 2 2 ZPR1 zinc-finger domain DUF866 PF05907.13 EAQ83773.1 - 1.8e-31 109.2 0.3 1.9e-31 109.1 0.3 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) GDPD PF03009.17 EAQ83775.1 - 8.4e-66 222.3 0.0 4.7e-65 219.9 0.0 2.1 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.7 EAQ83775.1 - 1.5e-36 124.9 1.4 6.7e-17 61.9 0.0 3.8 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAQ83775.1 - 2.6e-25 88.5 0.9 1.2e-07 32.1 0.0 5.3 5 0 0 5 5 5 4 Ankyrin repeats (many copies) SPX PF03105.19 EAQ83775.1 - 7.4e-21 75.5 10.2 1.7e-10 41.4 0.0 3.9 3 1 1 4 4 4 3 SPX domain Ank_5 PF13857.6 EAQ83775.1 - 3e-19 68.8 0.1 9.3e-07 29.0 0.0 4.6 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 EAQ83775.1 - 2.3e-17 62.6 0.2 8.6e-05 22.8 0.0 5.8 5 0 0 5 5 5 2 Ankyrin repeat Ank_3 PF13606.6 EAQ83775.1 - 1e-15 56.3 0.8 0.0013 19.0 0.0 6.0 6 0 0 6 6 6 3 Ankyrin repeat DUF3439 PF11921.8 EAQ83775.1 - 0.026 14.5 16.3 0.073 13.0 16.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) DLIC PF05783.11 EAQ83775.1 - 0.13 11.1 0.5 0.28 10.0 0.5 1.5 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Dicty_REP PF05086.12 EAQ83775.1 - 4.3 5.2 8.5 6.4 4.6 8.5 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein WW PF00397.26 EAQ83776.1 - 1.9e-09 37.4 0.1 3.5e-09 36.6 0.1 1.5 1 0 0 1 1 1 1 WW domain Pga1 PF10333.9 EAQ83777.1 - 8.9e-05 22.4 1.1 0.001 18.9 1.1 2.6 1 1 0 1 1 1 1 GPI-Mannosyltransferase II co-activator ABC_membrane_2 PF06472.15 EAQ83778.1 - 4.4e-99 331.2 1.8 7e-99 330.6 1.8 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 EAQ83778.1 - 2.5e-17 63.7 0.0 5.4e-17 62.6 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EAQ83778.1 - 0.00022 21.1 0.0 0.00066 19.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EAQ83778.1 - 0.028 14.8 0.5 0.51 10.7 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain SbmA_BacA PF05992.12 EAQ83778.1 - 0.061 12.8 0.6 0.12 11.8 0.6 1.5 1 0 0 1 1 1 0 SbmA/BacA-like family SMC_N PF02463.19 EAQ83778.1 - 0.064 12.7 0.1 0.25 10.7 0.0 2.0 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EAQ83778.1 - 0.085 13.3 0.8 0.2 12.2 0.0 1.9 3 0 0 3 3 3 0 AAA domain Glyco_transf_22 PF03901.17 EAQ83778.1 - 0.11 11.7 0.9 0.18 11.0 0.9 1.3 1 0 0 1 1 1 0 Alg9-like mannosyltransferase family AAA_29 PF13555.6 EAQ83778.1 - 0.11 12.3 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 EAQ83778.1 - 0.15 12.3 0.0 1.7 8.9 0.0 2.7 3 0 0 3 3 3 0 AAA domain DUF5476 PF17570.2 EAQ83779.1 - 5 7.6 7.6 0.85 10.1 2.5 2.6 2 1 0 2 2 2 0 Family of unknown function (DUF5476) G_glu_transpept PF01019.21 EAQ83780.1 - 5.7e-96 322.3 6.7 9.6e-53 179.7 0.1 3.1 1 1 2 3 3 3 3 Gamma-glutamyltranspeptidase ADH_N PF08240.12 EAQ83781.1 - 1.9e-28 98.5 0.2 3.4e-28 97.7 0.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EAQ83781.1 - 4.4e-24 84.9 0.1 7.8e-24 84.1 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EAQ83781.1 - 4.3e-05 24.6 0.0 7.7e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EAQ83781.1 - 0.0018 17.6 0.6 0.0026 17.1 0.6 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain adh_short PF00106.25 EAQ83781.1 - 0.048 13.1 0.3 0.11 12.0 0.3 1.6 1 0 0 1 1 1 0 short chain dehydrogenase 2-Hacid_dh_C PF02826.19 EAQ83781.1 - 0.13 11.6 0.3 0.22 10.9 0.3 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF2226 PF09987.9 EAQ83781.1 - 0.17 11.2 0.0 0.24 10.7 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2226) Actin PF00022.19 EAQ83782.1 - 4.8e-85 285.6 0.0 2.9e-52 177.7 0.0 2.0 1 1 1 2 2 2 2 Actin MreB_Mbl PF06723.13 EAQ83782.1 - 0.11 11.3 0.1 3.2 6.5 0.0 2.1 2 0 0 2 2 2 0 MreB/Mbl protein Asparaginase_2 PF01112.18 EAQ83783.1 - 3.6e-40 137.9 0.6 1.7e-25 89.7 0.0 2.3 2 0 0 2 2 2 2 Asparaginase Tfb4 PF03850.14 EAQ83784.1 - 1.2e-69 234.9 15.4 3.7e-48 164.4 3.5 2.5 2 1 1 3 3 3 3 Transcription factor Tfb4 UNC45-central PF11701.8 EAQ83785.1 - 6.3e-43 146.4 0.9 4e-42 143.8 0.0 2.9 4 1 1 5 5 5 1 Myosin-binding striated muscle assembly central Arm PF00514.23 EAQ83785.1 - 0.91 9.7 12.6 40 4.4 0.1 6.0 7 0 0 7 7 7 0 Armadillo/beta-catenin-like repeat ERCC4 PF02732.15 EAQ83786.1 - 9e-35 120.2 0.2 1.4e-34 119.6 0.2 1.3 1 0 0 1 1 1 1 ERCC4 domain FancD2 PF14631.6 EAQ83786.1 - 0.84 6.9 6.6 1.2 6.4 6.6 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease RR_TM4-6 PF06459.12 EAQ83786.1 - 4.7 6.9 8.6 9.6 5.9 8.6 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Ntox10 PF15520.6 EAQ83787.1 - 0.21 11.5 0.0 0.23 11.3 0.0 1.1 1 0 0 1 1 1 0 Novel toxin 10 Kinesin PF00225.23 EAQ83788.1 - 8.4e-94 314.2 1.3 3.2e-93 312.3 0.0 2.8 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 EAQ83788.1 - 6.5e-18 65.1 0.0 4.4e-14 52.7 0.0 3.3 1 1 1 2 2 2 2 Microtubule binding AMP-binding_C PF13193.6 EAQ83789.1 - 7.3e-21 74.9 0.3 1.1e-20 74.4 0.3 1.2 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 EAQ83789.1 - 0.00034 19.3 0.7 0.00049 18.8 0.7 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Reprolysin_2 PF13574.6 EAQ83790.1 - 4e-54 183.5 0.1 6.7e-54 182.7 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 EAQ83790.1 - 6.1e-53 179.9 1.4 6.1e-53 179.9 1.4 2.0 2 1 1 3 3 3 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 EAQ83790.1 - 3.7e-39 134.5 0.1 7e-39 133.6 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 EAQ83790.1 - 6e-12 46.2 0.0 1.2e-11 45.2 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.23 EAQ83790.1 - 3.9e-05 24.3 28.8 3.9e-05 24.3 28.8 4.2 2 2 0 2 2 2 1 Disintegrin NuiA PF07924.11 EAQ83792.1 - 0.004 17.6 0.1 0.53 10.7 0.1 2.3 1 1 0 1 1 1 1 Nuclease A inhibitor-like protein Ribosomal_L3 PF00297.22 EAQ83793.1 - 3.7e-183 608.6 13.0 4.3e-183 608.4 13.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 TPR_1 PF00515.28 EAQ83794.1 - 3.1e-56 185.0 26.7 6.6e-08 32.1 0.0 10.5 10 1 0 10 10 10 8 Tetratricopeptide repeat TPR_2 PF07719.17 EAQ83794.1 - 1.4e-51 168.5 18.1 1.6e-05 24.7 1.2 10.4 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_8 PF13181.6 EAQ83794.1 - 1.1e-38 128.1 16.8 2.3e-05 24.2 0.0 10.6 10 1 0 10 10 10 7 Tetratricopeptide repeat TPR_14 PF13428.6 EAQ83794.1 - 1.2e-30 103.5 11.1 0.00058 20.5 0.0 9.5 2 2 7 9 9 9 8 Tetratricopeptide repeat TPR_17 PF13431.6 EAQ83794.1 - 1.2e-28 97.4 12.0 0.00047 20.3 0.1 9.9 8 2 2 10 10 10 6 Tetratricopeptide repeat TPR_12 PF13424.6 EAQ83794.1 - 2.5e-27 95.0 14.5 1.3e-05 25.4 0.7 7.2 4 1 2 6 6 6 5 Tetratricopeptide repeat TPR_11 PF13414.6 EAQ83794.1 - 7.3e-26 89.6 24.9 1.1e-05 25.0 0.1 9.8 6 2 3 9 9 9 6 TPR repeat TPR_19 PF14559.6 EAQ83794.1 - 1e-25 90.0 11.9 0.00017 22.0 0.1 7.1 4 2 4 8 8 8 7 Tetratricopeptide repeat TPR_16 PF13432.6 EAQ83794.1 - 4.4e-25 88.0 14.9 2.1e-06 28.3 0.1 7.5 5 1 3 8 8 7 7 Tetratricopeptide repeat TPR_6 PF13174.6 EAQ83794.1 - 5.5e-23 80.0 11.1 0.014 16.0 0.9 9.3 10 0 0 10 10 9 5 Tetratricopeptide repeat TPR_7 PF13176.6 EAQ83794.1 - 3.9e-19 67.2 8.7 0.016 15.2 0.1 9.3 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_9 PF13371.6 EAQ83794.1 - 2.3e-16 59.7 15.4 0.0092 16.1 0.2 7.1 1 1 7 8 8 8 4 Tetratricopeptide repeat ANAPC3 PF12895.7 EAQ83794.1 - 3.3e-13 49.7 16.3 8.4e-08 32.3 2.1 3.5 2 1 2 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 EAQ83794.1 - 2.2e-11 43.5 6.0 0.0085 15.3 0.1 5.0 1 1 3 5 5 5 3 Tetratricopeptide repeat TPR_21 PF09976.9 EAQ83794.1 - 1.5e-07 31.3 4.0 0.062 13.0 0.0 4.8 4 2 0 4 4 4 2 Tetratricopeptide repeat-like domain TPR_MalT PF17874.1 EAQ83794.1 - 0.011 15.1 2.6 0.14 11.5 0.4 3.0 2 1 1 3 3 3 0 MalT-like TPR region NARP1 PF12569.8 EAQ83794.1 - 0.018 13.9 7.0 1.1 8.1 0.0 4.1 4 1 0 4 4 4 0 NMDA receptor-regulated protein 1 BTAD PF03704.17 EAQ83794.1 - 0.023 15.1 15.7 1.1 9.6 0.1 4.0 4 0 0 4 4 4 0 Bacterial transcriptional activator domain RPN7 PF10602.9 EAQ83794.1 - 0.024 14.3 4.2 1.2 8.8 0.0 4.2 4 1 1 5 5 5 0 26S proteasome subunit RPN7 TPR_20 PF14561.6 EAQ83794.1 - 0.027 14.8 7.0 1.1 9.7 0.0 4.5 5 1 1 6 6 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 EAQ83794.1 - 0.14 12.1 23.8 3.5 7.6 0.1 8.0 9 0 0 9 9 9 0 Tetratricopeptide repeat ChAPs PF09295.10 EAQ83794.1 - 0.33 9.9 1.5 2.2 7.2 0.2 2.7 3 1 1 4 4 4 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_3 PF07720.12 EAQ83794.1 - 1.2 9.2 18.0 9.2 6.4 0.2 5.2 5 0 0 5 5 4 0 Tetratricopeptide repeat SNAP PF14938.6 EAQ83794.1 - 3 7.2 14.9 25 4.2 0.4 4.9 2 2 2 4 4 4 0 Soluble NSF attachment protein, SNAP DUF1751 PF08551.10 EAQ83796.1 - 1e-28 99.8 2.8 2.2e-28 98.7 2.8 1.6 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.22 EAQ83796.1 - 0.23 11.5 8.1 0.48 10.4 8.1 1.5 1 0 0 1 1 1 0 Rhomboid family ANAPC4_WD40 PF12894.7 EAQ83797.1 - 8e-12 45.3 0.1 0.0018 18.5 0.0 5.3 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EAQ83797.1 - 7.7e-11 42.4 7.4 0.0064 17.3 0.0 7.1 6 1 1 7 7 7 3 WD domain, G-beta repeat LisH PF08513.11 EAQ83797.1 - 8.5e-08 31.9 0.1 1.8e-07 30.9 0.1 1.6 1 0 0 1 1 1 1 LisH MFS_1 PF07690.16 EAQ83798.1 - 1.6e-36 126.0 43.2 1.6e-36 126.0 43.2 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EAQ83798.1 - 1.3e-13 50.7 8.4 1.3e-13 50.7 8.4 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter DUF1072 PF06380.11 EAQ83798.1 - 8.8 6.3 6.4 0.55 10.1 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1072) Sugar_tr PF00083.24 EAQ83799.1 - 2.3e-39 135.5 10.2 2.5e-39 135.4 10.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EAQ83799.1 - 0.00042 19.4 25.8 0.00096 18.2 25.8 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF3188 PF11384.8 EAQ83799.1 - 0.16 11.7 2.9 0.15 11.8 0.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3188) adh_short PF00106.25 EAQ83800.1 - 2.6e-38 131.5 0.6 4e-38 130.8 0.6 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EAQ83800.1 - 2.1e-31 109.3 0.2 3.1e-31 108.7 0.2 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EAQ83800.1 - 1.3e-10 41.5 4.5 1.9e-09 37.7 4.5 2.2 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EAQ83800.1 - 0.0081 15.7 0.1 0.014 14.9 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 EAQ83800.1 - 0.028 13.8 0.1 0.045 13.1 0.1 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) HDPD PF02924.14 EAQ83800.1 - 0.15 12.2 0.2 0.15 12.2 0.2 1.8 2 0 0 2 2 2 0 Bacteriophage lambda head decoration protein D Pkinase PF00069.25 EAQ83801.1 - 6.4e-06 25.7 0.0 6.6e-05 22.4 0.0 2.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ83801.1 - 0.11 11.8 0.0 0.48 9.7 0.0 2.0 2 1 0 2 2 2 0 Protein tyrosine kinase Sof1 PF04158.14 EAQ83803.1 - 4.9e-32 110.0 12.6 8.9e-32 109.2 12.6 1.4 1 0 0 1 1 1 1 Sof1-like domain WD40 PF00400.32 EAQ83803.1 - 4.2e-24 84.4 10.5 7.8e-07 29.7 0.0 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAQ83803.1 - 1.6e-07 31.5 0.4 0.0086 16.4 0.0 4.2 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 EAQ83803.1 - 0.00043 20.3 0.0 17 5.5 0.0 4.2 2 1 2 4 4 4 1 Ciliary BBSome complex subunit 2, middle region PQQ_3 PF13570.6 EAQ83803.1 - 0.057 13.9 0.7 5.6 7.6 0.0 4.1 5 0 0 5 5 5 0 PQQ-like domain RPN6_N PF18055.1 EAQ83804.1 - 1.3e-47 161.0 2.8 1.3e-47 160.9 0.5 2.2 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 EAQ83804.1 - 1.2e-19 70.8 0.9 4e-19 69.1 0.2 2.3 3 1 0 3 3 3 1 PCI domain RPN6_C_helix PF18503.1 EAQ83804.1 - 2.2e-10 40.1 0.6 2.2e-10 40.1 0.6 1.9 2 0 0 2 2 2 1 26S proteasome subunit RPN6 C-terminal helix domain TPR_7 PF13176.6 EAQ83804.1 - 9.7e-07 28.4 4.2 0.66 10.1 0.7 4.9 4 1 0 4 4 4 2 Tetratricopeptide repeat DDRGK PF09756.9 EAQ83804.1 - 0.00013 21.6 0.2 0.00031 20.4 0.2 1.6 1 0 0 1 1 1 1 DDRGK domain TPR_MalT PF17874.1 EAQ83804.1 - 0.0009 18.7 1.1 0.0009 18.7 1.1 2.3 2 1 0 2 2 2 1 MalT-like TPR region TPR_12 PF13424.6 EAQ83804.1 - 0.015 15.6 18.1 5.8 7.3 1.9 5.6 4 1 2 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.28 EAQ83804.1 - 0.021 14.6 5.8 3.7 7.5 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat HTH_Crp_2 PF13545.6 EAQ83804.1 - 0.047 13.7 0.1 0.45 10.5 0.0 2.6 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain TPR_10 PF13374.6 EAQ83804.1 - 0.11 12.4 3.3 4.1 7.4 0.1 4.1 3 1 1 4 4 4 0 Tetratricopeptide repeat Ribonuclease_P PF00825.18 EAQ83804.1 - 0.16 12.1 0.6 1.4 9.0 0.2 2.4 2 0 0 2 2 2 0 Ribonuclease P DUF87 PF01935.17 EAQ83804.1 - 0.23 11.5 1.9 0.78 9.8 0.2 2.3 2 1 0 2 2 2 0 Helicase HerA, central domain TPR_2 PF07719.17 EAQ83804.1 - 1.8 8.9 11.9 22 5.5 0.1 5.5 5 1 0 5 5 5 0 Tetratricopeptide repeat Sds3 PF08598.11 EAQ83807.1 - 1e-23 84.5 3.7 1.4e-23 84.0 3.7 1.2 1 0 0 1 1 1 1 Sds3-like Amidinotransf PF02274.17 EAQ83807.1 - 0.03 13.4 0.1 0.056 12.5 0.1 1.4 1 0 0 1 1 1 0 Amidinotransferase FAM184 PF15665.5 EAQ83807.1 - 1.6 8.4 7.4 5.1 6.8 7.4 1.9 1 1 0 1 1 1 0 Family with sequence similarity 184, A and B LSM PF01423.22 EAQ83808.1 - 7.9e-15 54.3 0.0 1.4e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 LSM domain Mob1_phocein PF03637.17 EAQ83810.1 - 3.5e-70 235.4 0.0 4.2e-70 235.2 0.0 1.1 1 0 0 1 1 1 1 Mob1/phocein family OSCP PF00213.18 EAQ83811.1 - 1.6e-42 145.5 0.8 2e-42 145.2 0.8 1.1 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit Glyco_hydro_63 PF03200.16 EAQ83812.1 - 5.8e-09 35.2 5.9 1.2e-07 30.9 2.5 3.7 2 1 0 2 2 2 1 Glycosyl hydrolase family 63 C-terminal domain PP2C PF00481.21 EAQ83813.1 - 1.9e-44 152.3 0.0 3.3e-44 151.5 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 EAQ83813.1 - 0.0019 17.9 0.1 0.0072 16.0 0.1 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 EAQ83813.1 - 0.004 17.1 0.0 0.19 11.6 0.0 2.6 3 0 0 3 3 3 1 Stage II sporulation protein E (SpoIIE) Toxin_35 PF10530.9 EAQ83814.1 - 0.00011 22.0 2.0 0.00012 21.9 2.0 1.1 1 0 0 1 1 1 1 Toxin with inhibitor cystine knot ICK or Knottin scaffold Conotoxin PF02950.17 EAQ83814.1 - 0.044 14.8 1.0 0.068 14.2 1.0 1.3 1 0 0 1 1 1 0 Conotoxin DUF5572 PF17733.1 EAQ83815.1 - 1.1e-15 57.1 2.1 3.1e-15 55.7 2.1 1.8 1 0 0 1 1 1 1 Family of unknown function (DUF5572) Molybdopterin PF00384.22 EAQ83816.1 - 2.8e-75 253.9 0.0 1.5e-73 248.2 0.0 2.1 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fer2_4 PF13510.6 EAQ83816.1 - 2.1e-20 72.5 0.1 6.2e-20 71.0 0.1 1.9 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH_dhqG_C PF09326.11 EAQ83816.1 - 3.1e-18 66.2 0.0 7.9e-18 64.9 0.0 1.7 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit G, C-terminal NADH-G_4Fe-4S_3 PF10588.9 EAQ83816.1 - 2.8e-17 62.0 0.2 2.8e-17 62.0 0.2 2.0 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2 PF00111.27 EAQ83816.1 - 8.7e-09 35.2 0.5 8.7e-09 35.2 0.5 2.0 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.22 EAQ83816.1 - 0.0064 16.2 0.0 0.2 11.4 0.0 2.4 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain ACBP PF00887.19 EAQ83818.1 - 8.7e-24 83.6 0.0 1.8e-23 82.6 0.0 1.5 1 0 0 1 1 1 1 Acyl CoA binding protein PRT_C PF08372.10 EAQ83818.1 - 0.096 12.4 0.1 0.15 11.8 0.1 1.3 1 0 0 1 1 1 0 Plant phosphoribosyltransferase C-terminal Ribonuclease_3 PF00636.26 EAQ83819.1 - 4.1e-14 53.1 0.0 9.3e-14 51.9 0.0 1.6 1 0 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 EAQ83819.1 - 3.6e-12 46.5 0.0 6.5e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease-III-like Staufen_C PF16482.5 EAQ83819.1 - 0.092 12.9 0.0 0.28 11.3 0.0 1.8 1 0 0 1 1 1 0 Staufen C-terminal domain WD40 PF00400.32 EAQ83820.1 - 2e-13 50.6 0.1 4.8e-10 39.9 0.0 2.9 2 0 0 2 2 2 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAQ83820.1 - 0.0075 16.5 0.1 0.017 15.4 0.1 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 EAQ83820.1 - 0.044 13.7 0.2 0.12 12.2 0.1 1.7 1 1 0 1 1 1 0 NACHT domain KAP_NTPase PF07693.14 EAQ83820.1 - 0.048 12.9 0.0 0.079 12.2 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain TPR_10 PF13374.6 EAQ83821.1 - 4.7e-40 134.4 0.0 6.3e-10 38.6 0.0 4.8 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_12 PF13424.6 EAQ83821.1 - 4.3e-30 103.8 0.5 1.4e-13 50.9 0.0 3.5 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.6 EAQ83821.1 - 3.1e-14 51.9 0.5 0.00036 20.3 0.0 4.7 5 0 0 5 5 4 3 Tetratricopeptide repeat NB-ARC PF00931.22 EAQ83821.1 - 2.8e-09 36.6 0.0 7e-09 35.2 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain TPR_2 PF07719.17 EAQ83821.1 - 5.2e-08 32.4 0.5 0.58 10.4 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_MalT PF17874.1 EAQ83821.1 - 6.1e-07 29.1 2.8 1.1e-06 28.2 2.8 1.4 1 0 0 1 1 1 1 MalT-like TPR region TPR_16 PF13432.6 EAQ83821.1 - 1.3e-06 29.0 1.0 0.19 12.4 0.0 4.6 5 1 0 5 5 3 2 Tetratricopeptide repeat TPR_4 PF07721.14 EAQ83821.1 - 5.1e-06 26.6 0.1 7.7 7.5 0.0 5.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 EAQ83821.1 - 1.2e-05 24.9 0.0 0.56 10.1 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 EAQ83821.1 - 2.5e-05 24.7 0.1 0.52 10.9 0.0 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 EAQ83821.1 - 0.00011 22.7 1.3 40 5.4 0.0 5.6 5 0 0 5 5 5 0 Tetratricopeptide repeat NACHT PF05729.12 EAQ83821.1 - 0.00052 20.0 0.0 0.001 19.0 0.0 1.5 1 0 0 1 1 1 1 NACHT domain TPR_8 PF13181.6 EAQ83821.1 - 0.00076 19.5 0.1 9.5 6.7 0.0 4.4 5 0 0 5 5 4 0 Tetratricopeptide repeat AAA_25 PF13481.6 EAQ83821.1 - 0.0026 17.3 0.0 0.0049 16.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain TPR_17 PF13431.6 EAQ83821.1 - 0.0039 17.5 0.1 0.55 10.7 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_5 PF12688.7 EAQ83821.1 - 0.071 13.4 0.0 4.8 7.4 0.0 2.8 1 1 1 2 2 2 0 Tetratrico peptide repeat AAA_16 PF13191.6 EAQ83821.1 - 0.094 13.1 1.7 0.47 10.8 0.3 2.7 2 1 0 2 2 2 0 AAA ATPase domain PPR PF01535.20 EAQ83821.1 - 0.14 12.4 0.4 62 4.2 0.1 3.7 4 0 0 4 4 3 0 PPR repeat HemY_N PF07219.13 EAQ83821.1 - 0.29 11.3 3.5 43 4.4 0.1 3.9 1 1 3 4 4 4 0 HemY protein N-terminus MRP-S33 PF08293.11 EAQ83822.1 - 3.1e-18 65.8 0.0 4.2e-18 65.3 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 PUF PF00806.19 EAQ83823.1 - 1.3e-37 125.4 0.4 3.4e-06 26.4 0.0 9.4 10 0 0 10 10 10 7 Pumilio-family RNA binding repeat RasGEF PF00617.19 EAQ83823.1 - 0.092 12.9 0.1 0.26 11.5 0.1 1.8 1 0 0 1 1 1 0 RasGEF domain UPF0061 PF02696.14 EAQ83824.1 - 5.5e-119 398.0 0.0 2.4e-115 386.0 0.0 2.0 2 0 0 2 2 2 2 Uncharacterized ACR, YdiU/UPF0061 family Aldo_ket_red PF00248.21 EAQ83825.1 - 9e-38 130.1 0.0 2.3e-36 125.5 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family XRCC4 PF06632.12 EAQ83826.1 - 3.9e-07 29.2 11.2 7.8e-07 28.3 11.2 1.4 1 1 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 DUF3585 PF12130.8 EAQ83826.1 - 0.0091 16.1 5.8 0.018 15.2 5.8 1.4 1 0 0 1 1 1 1 Bivalent Mical/EHBP Rab binding domain LUC7 PF03194.15 EAQ83826.1 - 0.022 14.4 3.0 0.039 13.6 3.0 1.4 1 0 0 1 1 1 0 LUC7 N_terminus HalX PF08663.10 EAQ83826.1 - 0.038 14.3 2.5 0.13 12.6 2.5 1.9 1 0 0 1 1 1 0 HalX domain CCDC106 PF15794.5 EAQ83826.1 - 0.53 10.0 15.5 0.16 11.7 7.5 2.2 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 DUF3086 PF11285.8 EAQ83826.1 - 1.4 7.9 5.5 0.64 9.1 3.1 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3086) Blt1 PF12754.7 EAQ83828.1 - 3.6e-50 170.2 0.0 8.3e-50 169.0 0.0 1.5 2 0 0 2 2 2 1 Blt1 N-terminal domain Blt1_C PF17183.4 EAQ83828.1 - 6.9e-22 76.8 0.2 1.1e-21 76.2 0.2 1.3 1 0 0 1 1 1 1 Get5 carboxyl domain ubiquitin PF00240.23 EAQ83828.1 - 0.00081 19.1 0.0 0.0012 18.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Mucin PF01456.17 EAQ83828.1 - 1.1 9.3 12.2 2 8.4 12.2 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Cofilin_ADF PF00241.20 EAQ83829.1 - 6.6e-42 142.1 0.8 7.4e-42 142.0 0.8 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Cpn60_TCP1 PF00118.24 EAQ83830.1 - 2.1e-82 277.3 10.1 2.9e-81 273.6 10.1 1.9 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family Cytomega_UL84 PF06284.11 EAQ83832.1 - 0.055 11.9 0.6 0.078 11.4 0.6 1.3 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein Pol_alpha_B_N PF08418.10 EAQ83832.1 - 1.2 9.0 7.9 2.1 8.3 8.0 1.5 1 1 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal MRI PF15325.6 EAQ83832.1 - 5.7 8.1 10.6 17 6.5 3.0 2.6 2 1 0 2 2 2 0 Modulator of retrovirus infection Inhibitor_I53 PF11714.8 EAQ83833.1 - 0.19 11.9 4.1 0.59 10.4 4.1 1.8 1 0 0 1 1 1 0 Thrombin inhibitor Madanin Pol_alpha_B_N PF08418.10 EAQ83833.1 - 0.66 9.9 7.8 0.85 9.5 7.8 1.1 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal RAP1 PF07218.11 EAQ83833.1 - 1.2 7.3 10.9 1.5 7.0 10.9 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF3246 PF11596.8 EAQ83833.1 - 4.1 6.8 12.0 3.4 7.0 8.8 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3246) Pneumo_att_G PF05539.11 EAQ83833.1 - 6.1 6.3 10.1 7.5 6.0 10.1 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G SRP-alpha_N PF04086.13 EAQ83833.1 - 6.4 6.6 13.0 8.6 6.2 13.0 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF4479 PF14794.6 EAQ83835.1 - 0.0067 16.3 0.0 0.01 15.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4479) Baculo_PEP_C PF04513.12 EAQ83840.1 - 6.7e-07 29.4 10.9 0.14 12.1 0.1 5.3 2 1 4 6 6 6 3 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.11 EAQ83840.1 - 1.7e-06 27.1 39.8 0.0049 15.8 18.6 4.6 1 1 2 4 4 4 3 Spc7 kinetochore protein DUF4407 PF14362.6 EAQ83840.1 - 0.0012 18.2 35.2 0.038 13.4 10.5 3.6 1 1 2 3 3 3 2 Domain of unknown function (DUF4407) DUF1664 PF07889.12 EAQ83840.1 - 0.0014 18.7 33.4 3.7 7.6 0.7 6.8 2 2 5 7 7 7 1 Protein of unknown function (DUF1664) PKcGMP_CC PF16808.5 EAQ83840.1 - 0.0017 18.2 1.5 0.0017 18.2 1.5 5.2 6 0 0 6 6 4 1 Coiled-coil N-terminus of cGMP-dependent protein kinase Syntaxin_2 PF14523.6 EAQ83840.1 - 0.02 15.2 1.6 0.02 15.2 1.6 5.1 1 1 2 4 4 3 0 Syntaxin-like protein MinE PF03776.14 EAQ83840.1 - 0.065 13.3 4.1 0.7 9.9 2.2 2.7 2 0 0 2 2 2 0 Septum formation topological specificity factor MinE TSP_NTD PF17804.1 EAQ83840.1 - 0.22 11.7 18.2 1.6 9.0 11.8 3.0 2 0 0 2 2 2 0 Tail specific protease N-terminal domain Fib_alpha PF08702.10 EAQ83840.1 - 0.36 11.0 25.1 1.9 8.7 8.0 4.9 1 1 5 6 6 6 0 Fibrinogen alpha/beta chain family AIP3 PF03915.13 EAQ83840.1 - 0.56 9.2 39.3 1.5 7.8 27.3 3.6 1 1 1 2 2 2 0 Actin interacting protein 3 TPR_MLP1_2 PF07926.12 EAQ83840.1 - 0.78 9.8 51.8 0.32 11.1 1.6 6.0 3 1 3 6 6 6 0 TPR/MLP1/MLP2-like protein FapA PF03961.13 EAQ83840.1 - 1.3 7.5 24.3 1.5 7.4 15.6 3.0 1 1 3 4 4 4 0 Flagellar Assembly Protein A AAA_13 PF13166.6 EAQ83840.1 - 1.4 7.5 36.0 0.21 10.2 22.1 3.1 1 1 3 4 4 4 0 AAA domain Peroxidase_2 PF01328.17 EAQ83840.1 - 2.8 8.4 6.6 6.8 7.2 5.7 1.9 1 1 0 1 1 1 0 Peroxidase, family 2 DUF948 PF06103.11 EAQ83840.1 - 3.7 7.9 23.2 0.72 10.2 0.4 5.9 4 1 2 6 6 5 0 Bacterial protein of unknown function (DUF948) Atg14 PF10186.9 EAQ83840.1 - 3.7 6.5 31.9 0.099 11.7 6.5 3.3 1 1 1 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 Ubiq_cyt_C_chap PF03981.12 EAQ83840.1 - 4 7.5 8.3 17 5.5 8.0 2.3 1 1 0 1 1 1 0 Ubiquinol-cytochrome C chaperone KxDL PF10241.9 EAQ83840.1 - 5.1 7.4 32.1 1.7 8.9 0.1 6.3 5 2 1 7 7 7 0 Uncharacterized conserved protein DUF3829 PF12889.7 EAQ83840.1 - 6.3 6.2 22.5 1.2 8.6 16.5 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF3829) Spore_III_AF PF09581.10 EAQ83840.1 - 7.4 6.6 21.7 4.7 7.2 17.5 2.6 1 1 1 2 2 2 0 Stage III sporulation protein AF (Spore_III_AF) HTH_Tnp_Tc3_2 PF01498.18 EAQ83841.1 - 2.6e-21 75.6 1.7 2.6e-21 75.6 1.7 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 EAQ83841.1 - 1.2e-12 47.9 0.2 2.7e-12 46.7 0.2 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.6 EAQ83841.1 - 2.1e-06 27.6 2.2 3e-05 23.9 0.5 2.6 2 0 0 2 2 2 1 Winged helix-turn helix HTH_32 PF13565.6 EAQ83841.1 - 3.4e-06 27.6 2.9 7e-06 26.6 1.2 2.3 1 1 1 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 EAQ83841.1 - 0.00094 19.3 1.0 0.0078 16.3 0.2 2.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 EAQ83841.1 - 0.012 15.4 0.2 0.012 15.4 0.2 2.8 4 0 0 4 4 4 0 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.6 EAQ83841.1 - 0.016 14.6 8.8 0.028 13.8 0.3 3.9 4 0 0 4 4 4 0 Helix-turn-helix domain of transposase family ISL3 HTH_7 PF02796.15 EAQ83841.1 - 0.017 15.2 0.0 0.19 11.8 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase CENP-B_N PF04218.13 EAQ83841.1 - 0.036 13.7 0.2 1.6 8.4 0.0 3.2 3 0 0 3 3 3 0 CENP-B N-terminal DNA-binding domain HTH_38 PF13936.6 EAQ83841.1 - 0.045 13.5 0.0 0.045 13.5 0.0 2.4 3 0 0 3 3 3 0 Helix-turn-helix domain TIP49 PF06068.13 EAQ83842.1 - 3.6e-155 516.5 2.1 4.7e-155 516.1 2.1 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 EAQ83842.1 - 1.2e-21 76.6 0.2 4.1e-21 74.9 0.2 2.0 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 EAQ83842.1 - 1.4e-08 35.3 0.3 3.3e-05 24.3 0.1 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EAQ83842.1 - 6.8e-08 32.4 0.5 4.8e-05 23.2 0.1 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain DnaB_C PF03796.15 EAQ83842.1 - 1e-06 28.3 1.0 1.9e-06 27.4 1.0 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_16 PF13191.6 EAQ83842.1 - 2.8e-06 27.8 0.5 7e-06 26.5 0.1 1.9 2 1 0 2 2 2 1 AAA ATPase domain Mg_chelatase PF01078.21 EAQ83842.1 - 0.0013 18.2 0.6 0.019 14.3 0.4 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 EAQ83842.1 - 0.0091 15.7 0.0 3.1 7.5 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_22 PF13401.6 EAQ83842.1 - 0.011 16.0 0.0 1.2 9.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 EAQ83842.1 - 0.017 15.1 0.2 2.3 8.2 0.0 2.9 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 EAQ83842.1 - 0.031 14.5 0.0 0.069 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAQ83842.1 - 0.033 13.8 0.1 0.068 12.7 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 EAQ83842.1 - 0.048 14.0 3.0 1.4 9.2 3.0 2.6 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.6 EAQ83842.1 - 0.048 13.4 1.0 0.23 11.2 1.0 2.0 1 1 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 EAQ83842.1 - 0.1 11.6 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_7 PF12775.7 EAQ83842.1 - 0.11 11.9 0.2 0.47 9.9 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_33 PF13671.6 EAQ83842.1 - 0.13 12.4 0.0 0.4 10.8 0.0 1.8 2 0 0 2 2 1 0 AAA domain GYF PF02213.16 EAQ83843.1 - 2.9e-10 39.6 1.3 6.9e-10 38.4 1.3 1.6 1 0 0 1 1 1 1 GYF domain UFD1 PF03152.14 EAQ83844.1 - 1.4e-62 210.2 0.0 1.7e-62 209.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 LRR_4 PF12799.7 EAQ83845.1 - 0.0022 18.4 8.2 0.022 15.2 0.1 4.4 6 0 0 6 6 6 2 Leucine Rich repeats (2 copies) VEFS-Box PF09733.9 EAQ83846.1 - 6.3e-09 35.8 1.2 1.4e-08 34.7 0.1 2.0 2 0 0 2 2 2 1 VEFS-Box of polycomb protein PHD PF00628.29 EAQ83846.1 - 0.0044 16.9 9.8 0.0044 16.9 9.8 1.9 2 0 0 2 2 2 1 PHD-finger DUF382 PF04037.13 EAQ83847.1 - 2e-60 202.5 0.8 2e-60 202.5 0.8 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF382) PSP PF04046.16 EAQ83847.1 - 1.1e-20 73.2 2.6 2.6e-20 72.0 2.6 1.7 1 0 0 1 1 1 1 PSP TPT PF03151.16 EAQ83848.1 - 9e-56 189.3 2.1 1.1e-55 189.0 2.1 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EAQ83848.1 - 1.1e-10 41.9 21.9 3.3e-06 27.3 8.9 3.1 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 EAQ83848.1 - 1.6e-06 27.5 5.4 0.0019 17.5 0.5 2.2 2 0 0 2 2 2 2 UAA transporter family Multi_Drug_Res PF00893.19 EAQ83848.1 - 0.2 12.3 3.9 2.2 9.0 1.2 3.1 3 0 0 3 3 3 0 Small Multidrug Resistance protein Fzo_mitofusin PF04799.13 EAQ83848.1 - 1.1 8.8 2.5 2.3 7.7 0.1 2.2 2 0 0 2 2 2 0 fzo-like conserved region ORC5_C PF14630.6 EAQ83849.1 - 2.4e-28 99.5 0.4 3.4e-28 99.0 0.4 1.2 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.6 EAQ83849.1 - 2.3e-15 57.4 0.0 6.4e-15 56.0 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_28 PF13521.6 EAQ83849.1 - 0.0056 16.9 0.1 0.037 14.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain TniB PF05621.11 EAQ83849.1 - 0.018 14.5 0.0 0.028 13.8 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein AAA_22 PF13401.6 EAQ83849.1 - 0.024 14.9 0.0 0.061 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EAQ83849.1 - 0.032 14.8 0.0 0.069 13.7 0.0 1.5 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 EAQ83849.1 - 0.065 12.4 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RecA PF00154.21 EAQ83849.1 - 0.15 11.5 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 recA bacterial DNA recombination protein Zn_clus PF00172.18 EAQ83850.1 - 1.1e-07 31.8 6.9 1.8e-07 31.2 6.9 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EAQ83850.1 - 3.2e-05 22.9 0.0 4.5e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain ATP-synt_ab PF00006.25 EAQ83851.1 - 9.7e-62 208.4 0.0 1.5e-61 207.8 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 EAQ83851.1 - 1.7e-22 79.7 0.4 5.8e-22 78.0 0.2 2.0 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain RsgA_GTPase PF03193.16 EAQ83851.1 - 0.0099 15.8 0.4 0.029 14.3 0.1 1.8 2 0 0 2 2 2 1 RsgA GTPase T3SS_ATPase_C PF18269.1 EAQ83851.1 - 0.016 15.1 1.0 0.09 12.7 1.0 2.1 1 1 0 1 1 1 0 T3SS EscN ATPase C-terminal domain NB-ARC PF00931.22 EAQ83851.1 - 0.016 14.4 0.6 0.082 12.1 0.1 2.0 2 0 0 2 2 2 0 NB-ARC domain ATPase_2 PF01637.18 EAQ83851.1 - 0.018 15.0 0.0 0.049 13.5 0.0 1.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA PF00004.29 EAQ83851.1 - 0.021 15.2 0.1 0.76 10.2 0.0 2.6 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 EAQ83851.1 - 0.04 13.3 0.1 0.07 12.5 0.1 1.4 1 0 0 1 1 1 0 KaiC AAA_19 PF13245.6 EAQ83851.1 - 0.047 14.0 0.6 0.48 10.7 0.2 2.4 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EAQ83851.1 - 0.049 13.5 0.1 0.13 12.2 0.0 1.7 2 0 0 2 2 2 0 NACHT domain RNA_helicase PF00910.22 EAQ83851.1 - 0.08 13.3 0.0 0.17 12.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_16 PF13191.6 EAQ83851.1 - 0.15 12.4 0.1 0.52 10.7 0.1 1.9 1 1 0 1 1 1 0 AAA ATPase domain Alpha-amylase_C PF02806.18 EAQ83852.1 - 2.8e-24 85.4 0.0 8.4e-24 83.9 0.0 1.8 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain zf-CHCC PF10276.9 EAQ83852.1 - 0.2 11.8 1.4 2.7 8.1 0.1 2.8 3 0 0 3 3 3 0 Zinc-finger domain AAA_2 PF07724.14 EAQ83854.1 - 1.6e-33 116.2 0.0 6.9e-33 114.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 EAQ83854.1 - 4.5e-13 49.8 0.0 1e-12 48.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 EAQ83854.1 - 3.3e-10 39.9 0.0 8.2e-10 38.6 0.0 1.6 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 EAQ83854.1 - 6.4e-08 32.7 0.0 1.4e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) MCM PF00493.23 EAQ83854.1 - 3.4e-05 23.1 0.0 6.7e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain AAA_22 PF13401.6 EAQ83854.1 - 0.00014 22.1 2.0 0.00084 19.6 0.2 2.9 2 1 0 2 2 2 1 AAA domain AAA_7 PF12775.7 EAQ83854.1 - 0.00082 18.9 0.0 0.0015 18.1 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_14 PF13173.6 EAQ83854.1 - 0.0016 18.5 0.4 0.0044 17.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EAQ83854.1 - 0.0027 18.1 0.1 0.01 16.2 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 EAQ83854.1 - 0.01 16.4 0.0 0.032 14.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EAQ83854.1 - 0.011 15.5 0.1 0.03 14.1 0.0 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 EAQ83854.1 - 0.035 13.5 0.0 1 8.7 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_15 PF13175.6 EAQ83854.1 - 0.039 13.7 0.1 0.076 12.7 0.1 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 EAQ83854.1 - 0.056 13.2 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain TniB PF05621.11 EAQ83854.1 - 0.065 12.6 0.1 0.47 9.8 0.0 2.1 2 0 0 2 2 2 0 Bacterial TniB protein Sigma54_activat PF00158.26 EAQ83854.1 - 0.066 12.9 0.0 0.71 9.6 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_19 PF13245.6 EAQ83854.1 - 0.072 13.4 0.3 0.46 10.8 0.0 2.3 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.27 EAQ83854.1 - 0.078 13.5 0.5 0.19 12.2 0.0 1.8 2 0 0 2 2 2 0 ABC transporter Rad17 PF03215.15 EAQ83854.1 - 0.12 12.2 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_24 PF13479.6 EAQ83854.1 - 0.13 12.0 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 EAQ83854.1 - 0.16 11.0 0.0 0.27 10.3 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein WD40 PF00400.32 EAQ83855.1 - 5.6e-19 68.1 14.5 1.3e-07 32.2 0.0 6.9 6 2 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAQ83855.1 - 0.00013 22.2 2.1 0.93 9.8 0.0 4.1 5 1 0 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EAQ83855.1 - 0.05 12.6 0.0 10 5.0 0.0 2.7 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Coatomer_WDAD PF04053.14 EAQ83855.1 - 0.1 11.6 0.2 2.4 7.1 0.0 2.0 2 0 0 2 2 2 0 Coatomer WD associated region Transket_pyr PF02779.24 EAQ83856.1 - 8.3e-64 214.5 0.0 1.8e-63 213.5 0.0 1.6 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 EAQ83856.1 - 4.4e-60 203.2 0.0 6.2e-60 202.7 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 EAQ83856.1 - 8.3e-57 191.2 0.1 1.4e-56 190.4 0.1 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 EAQ83856.1 - 2.2e-19 68.7 1.4 4.9e-19 67.6 1.4 1.6 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus YceG_bac PF14266.6 EAQ83856.1 - 0.13 11.2 0.1 0.19 10.6 0.1 1.2 1 0 0 1 1 1 0 Putative component of 'biosynthetic module' BSD PF03909.17 EAQ83857.1 - 7.8e-27 93.1 4.2 1.9e-12 47.0 0.6 2.9 3 0 0 3 3 3 2 BSD domain PH_TFIIH PF08567.11 EAQ83857.1 - 6.6e-24 84.1 0.0 1.9e-23 82.6 0.0 1.8 2 0 0 2 2 2 1 TFIIH p62 subunit, N-terminal domain AAA PF00004.29 EAQ83858.1 - 5.3e-37 127.2 0.0 3e-36 124.8 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EAQ83858.1 - 1.5e-10 40.7 0.0 4.8e-10 39.1 0.0 1.9 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 EAQ83858.1 - 3e-05 24.4 1.4 0.00028 21.3 0.3 3.0 2 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 EAQ83858.1 - 6.8e-05 22.7 0.0 0.00016 21.4 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EAQ83858.1 - 0.00066 20.0 0.1 0.047 14.0 0.1 2.8 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 EAQ83858.1 - 0.00071 19.6 0.0 0.0059 16.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EAQ83858.1 - 0.0017 18.5 0.0 0.0076 16.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 EAQ83858.1 - 0.0058 16.4 0.0 0.014 15.1 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_5 PF07728.14 EAQ83858.1 - 0.013 15.5 0.0 0.045 13.7 0.0 2.1 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 EAQ83858.1 - 0.023 14.4 0.0 0.076 12.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain TIP49 PF06068.13 EAQ83858.1 - 0.025 13.8 0.0 0.042 13.1 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain Mg_chelatase PF01078.21 EAQ83858.1 - 0.028 13.8 0.0 0.076 12.4 0.0 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 EAQ83858.1 - 0.029 14.9 0.0 0.13 12.8 0.0 2.1 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EAQ83858.1 - 0.039 14.3 0.0 0.12 12.8 0.0 1.8 2 0 0 2 2 1 0 RNA helicase Sigma54_activat PF00158.26 EAQ83858.1 - 0.058 13.1 0.2 0.55 9.9 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_28 PF13521.6 EAQ83858.1 - 0.09 13.0 0.1 0.34 11.1 0.0 2.1 2 0 0 2 2 1 0 AAA domain AAA_7 PF12775.7 EAQ83858.1 - 0.18 11.3 0.0 0.44 10.0 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region RVT_2 PF07727.14 EAQ83859.1 - 1.1e-30 107.1 0.0 2.3e-30 106.0 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 EAQ83859.1 - 1.5e-08 34.9 0.0 4.7e-08 33.2 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.6 EAQ83859.1 - 0.0014 18.5 0.0 0.0047 16.8 0.0 2.0 1 0 0 1 1 1 1 GAG-pre-integrase domain Retrotran_gag_2 PF14223.6 EAQ83859.1 - 0.0092 15.6 0.6 0.024 14.3 0.6 1.7 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type GST_C_3 PF14497.6 EAQ83859.1 - 0.063 13.5 5.5 0.28 11.4 1.7 3.0 3 0 0 3 3 3 0 Glutathione S-transferase, C-terminal domain PolC_DP2 PF03833.13 EAQ83859.1 - 0.76 7.6 4.3 1.2 6.9 4.3 1.2 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zinc_ribbon_15 PF17032.5 EAQ83859.1 - 3 8.7 7.8 1.8 9.4 3.5 2.4 2 0 0 2 2 2 0 zinc-ribbon family Mus7 PF09462.10 EAQ83860.1 - 2.9e-204 680.4 0.0 4.3e-204 679.9 0.0 1.2 1 0 0 1 1 1 1 Mus7/MMS22 family DUF4574 PF15141.6 EAQ83860.1 - 2 8.4 3.6 9.4 6.2 0.8 2.7 2 0 0 2 2 2 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 COX4 PF02936.14 EAQ83861.1 - 2.5e-48 163.6 0.2 2.9e-48 163.4 0.2 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV DUF1104 PF06518.11 EAQ83861.1 - 0.0046 17.3 0.7 0.0068 16.8 0.2 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1104) DAO_C PF16901.5 EAQ83863.1 - 3.4e-45 153.0 0.2 6.2e-45 152.1 0.2 1.5 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase DAO PF01266.24 EAQ83863.1 - 1.5e-30 106.9 0.0 2.4e-30 106.3 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase RGS PF00615.19 EAQ83864.1 - 3.4e-09 37.0 0.0 5.5e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain Peptidase_C48 PF02902.19 EAQ83867.1 - 9.1e-15 55.1 0.0 1.8e-14 54.1 0.0 1.5 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DDRGK PF09756.9 EAQ83867.1 - 1.2 8.7 22.2 2.5 7.7 22.2 1.5 1 0 0 1 1 1 0 DDRGK domain CDC45 PF02724.14 EAQ83867.1 - 5 5.3 9.7 7.6 4.7 9.7 1.2 1 0 0 1 1 1 0 CDC45-like protein eIF3_subunit PF08597.10 EAQ83867.1 - 7.2 6.4 16.2 0.092 12.6 8.5 1.7 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit Cupin_8 PF13621.6 EAQ83869.1 - 3.5e-13 49.9 0.0 3.1e-08 33.7 0.0 2.3 1 1 1 2 2 2 2 Cupin-like domain Kelch_4 PF13418.6 EAQ83869.1 - 1.7e-12 47.1 12.4 2.3e-10 40.3 0.2 4.6 5 0 0 5 5 5 2 Galactose oxidase, central domain LCM PF04072.14 EAQ83869.1 - 6.4e-11 42.5 0.0 1.3e-07 31.7 0.0 2.4 1 1 1 2 2 2 2 Leucine carboxyl methyltransferase Kelch_6 PF13964.6 EAQ83869.1 - 9.5e-07 28.9 3.4 0.0013 18.9 0.0 3.8 3 1 1 4 4 4 2 Kelch motif Cupin_4 PF08007.12 EAQ83869.1 - 0.00036 20.1 0.2 0.00073 19.1 0.2 1.4 1 0 0 1 1 1 1 Cupin superfamily protein Kelch_1 PF01344.25 EAQ83869.1 - 0.0034 16.9 0.6 0.99 9.0 0.0 3.3 3 0 0 3 3 3 1 Kelch motif Kelch_3 PF13415.6 EAQ83869.1 - 0.018 15.3 0.2 0.018 15.3 0.2 3.5 5 0 0 5 5 5 0 Galactose oxidase, central domain Kelch_5 PF13854.6 EAQ83869.1 - 0.14 12.2 0.9 1.5 8.9 0.1 3.0 3 0 0 3 3 3 0 Kelch motif Kelch_2 PF07646.15 EAQ83869.1 - 0.41 10.7 6.2 13 5.9 0.8 3.5 4 0 0 4 4 4 0 Kelch motif Mito_carr PF00153.27 EAQ83870.1 - 7.5e-38 128.4 10.9 1.9e-15 56.6 0.2 3.5 2 1 2 4 4 4 3 Mitochondrial carrier protein MFS_1 PF07690.16 EAQ83871.1 - 3.9e-24 85.2 62.9 1.7e-18 66.7 40.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 EAQ83872.1 - 4.6e-14 52.1 29.2 4.6e-14 52.1 29.2 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Nodulin-like PF06813.13 EAQ83872.1 - 0.00015 21.3 9.1 0.00042 19.9 4.7 2.9 2 1 0 2 2 2 1 Nodulin-like NapE PF06796.11 EAQ83872.1 - 3.2 7.3 8.6 0.45 10.1 0.4 3.5 5 0 0 5 5 5 0 Periplasmic nitrate reductase protein NapE His_Phos_2 PF00328.22 EAQ83873.1 - 0.0097 15.3 0.4 0.0097 15.3 0.4 2.1 2 1 0 2 2 2 1 Histidine phosphatase superfamily (branch 2) SKG6 PF08693.10 EAQ83874.1 - 0.0027 17.1 0.4 0.0062 15.9 0.4 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4229 PF14012.6 EAQ83874.1 - 0.15 12.1 0.4 0.31 11.2 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4229) LSM PF01423.22 EAQ83875.1 - 3.3e-20 71.6 0.1 3.8e-20 71.3 0.1 1.1 1 0 0 1 1 1 1 LSM domain PRMT5_TIM PF17285.2 EAQ83876.1 - 8.4e-79 264.4 0.0 1.1e-78 264.0 0.0 1.2 1 0 0 1 1 1 1 PRMT5 TIM barrel domain PRMT5 PF05185.16 EAQ83876.1 - 3.6e-66 222.3 0.0 7.1e-66 221.3 0.0 1.4 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_C PF17286.2 EAQ83876.1 - 1.9e-61 207.0 0.1 4e-61 206.0 0.0 1.6 2 0 0 2 2 2 1 PRMT5 oligomerisation domain OB_NTP_bind PF07717.16 EAQ83877.1 - 9.5e-23 80.4 0.2 6.4e-22 77.7 0.1 2.4 3 0 0 3 3 3 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 EAQ83877.1 - 1.4e-17 64.0 0.0 3.4e-17 62.7 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EAQ83877.1 - 1.4e-10 41.4 0.0 7.2e-10 39.2 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 EAQ83877.1 - 1.9e-08 34.3 0.2 1.1e-07 31.9 0.1 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAQ83877.1 - 3.9e-08 33.7 0.1 1.2e-07 32.1 0.1 1.8 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 EAQ83877.1 - 0.00013 21.7 0.1 0.00052 19.7 0.1 1.9 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_30 PF13604.6 EAQ83877.1 - 0.0014 18.3 0.0 0.0026 17.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 EAQ83877.1 - 0.0021 18.1 0.0 0.46 10.5 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit T2SSE PF00437.20 EAQ83877.1 - 0.013 14.6 0.0 0.027 13.5 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA PF00004.29 EAQ83877.1 - 0.026 14.9 0.5 0.3 11.5 0.1 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 EAQ83877.1 - 0.031 14.8 0.0 0.063 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 EAQ83877.1 - 0.06 12.6 0.0 0.094 11.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_7 PF12775.7 EAQ83877.1 - 0.073 12.6 0.8 0.27 10.7 0.0 2.3 3 0 0 3 3 3 0 P-loop containing dynein motor region Flavi_DEAD PF07652.14 EAQ83877.1 - 0.14 12.2 0.0 0.33 10.9 0.0 1.6 1 0 0 1 1 1 0 Flavivirus DEAD domain RTP1_C1 PF10363.9 EAQ83880.1 - 5.3e-28 97.4 0.1 6.6e-27 93.9 0.0 2.8 3 0 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 RTP1_C2 PF10304.9 EAQ83880.1 - 7.9e-14 51.0 0.8 2e-13 49.7 0.8 1.7 1 0 0 1 1 1 1 Required for nuclear transport of RNA pol II C-terminus 2 AT_hook PF02178.19 EAQ83881.1 - 1.8 8.7 12.0 0.027 14.3 3.5 2.6 2 0 0 2 2 2 0 AT hook motif Nramp PF01566.18 EAQ83882.1 - 1.5e-67 228.1 16.1 2.5e-65 220.8 16.1 2.0 1 1 0 1 1 1 1 Natural resistance-associated macrophage protein DDHD PF02862.17 EAQ83883.1 - 7.3e-24 85.2 0.0 5.7e-12 46.3 0.0 3.2 2 1 1 3 3 3 2 DDHD domain Na_Ca_ex PF01699.24 EAQ83883.1 - 5.7e-23 81.6 33.6 3.3e-13 49.9 12.8 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein CDC45 PF02724.14 EAQ83883.1 - 0.013 13.8 0.5 0.019 13.3 0.5 1.1 1 0 0 1 1 1 0 CDC45-like protein SpoIIIAH PF12685.7 EAQ83883.1 - 0.18 11.6 0.0 0.28 11.0 0.0 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein HBB PF06777.11 EAQ83884.1 - 3.4e-48 163.9 0.7 2.9e-44 151.0 0.1 2.4 2 0 0 2 2 2 2 Helical and beta-bridge domain Helicase_C_2 PF13307.6 EAQ83884.1 - 5.6e-43 147.1 0.0 1.4e-42 145.7 0.0 1.7 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 EAQ83884.1 - 8.5e-37 126.5 9.7 8.3e-19 67.9 4.0 2.6 2 1 1 3 3 3 2 DEAD_2 ResIII PF04851.15 EAQ83884.1 - 9.8e-06 25.7 0.0 2.9e-05 24.1 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAQ83884.1 - 0.0013 18.5 0.1 0.0078 16.0 0.1 2.0 1 1 0 1 1 1 1 DEAD/DEAH box helicase SNF2_N PF00176.23 EAQ83884.1 - 0.019 13.7 0.2 0.16 10.7 0.2 2.0 1 1 0 1 1 1 0 SNF2 family N-terminal domain AAA_11 PF13086.6 EAQ83884.1 - 0.037 13.8 0.1 0.073 12.8 0.1 1.5 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.9 EAQ83884.1 - 0.096 11.9 0.3 4.5 6.4 0.3 2.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 EAQ83884.1 - 0.15 12.3 0.2 16 5.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain Integrin_B_tail PF07965.12 EAQ83884.1 - 0.18 12.3 0.4 0.35 11.4 0.4 1.4 1 0 0 1 1 1 0 Integrin beta tail domain zf-C2H2 PF00096.26 EAQ83888.1 - 6.4e-13 48.4 22.1 6.4e-05 23.2 0.7 3.8 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EAQ83888.1 - 3.2e-10 39.9 17.7 0.001 19.7 0.7 4.0 4 0 0 4 4 4 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EAQ83888.1 - 0.013 15.9 20.2 0.022 15.2 2.4 4.1 4 0 0 4 4 4 0 Zinc-finger double domain FOXP-CC PF16159.5 EAQ83888.1 - 0.18 12.5 4.9 2.2 9.0 1.7 2.4 2 0 0 2 2 2 0 FOXP coiled-coil domain zf-C2H2_jaz PF12171.8 EAQ83888.1 - 0.78 10.1 8.9 10 6.6 0.3 3.6 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_aberr PF17017.5 EAQ83888.1 - 1.1 9.4 5.4 1.5 9.0 0.3 2.5 1 1 2 3 3 3 0 Aberrant zinc-finger zf-C2H2_11 PF16622.5 EAQ83888.1 - 1.9 8.3 7.9 0.4 10.5 0.2 2.8 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-C2H2_8 PF15909.5 EAQ83888.1 - 2.6 8.4 12.1 0.89 9.9 7.3 2.6 3 1 1 4 4 4 0 C2H2-type zinc ribbon zf-met PF12874.7 EAQ83888.1 - 6.7 7.3 7.6 16 6.0 0.2 3.6 3 0 0 3 3 3 0 Zinc-finger of C2H2 type PRP3 PF08572.10 EAQ83889.1 - 8e-72 241.6 7.2 1.1e-71 241.1 7.2 1.2 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 EAQ83889.1 - 1.1e-46 158.5 0.1 1.1e-46 158.5 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) RNA_pol_Rpb1_5 PF04998.17 EAQ83890.1 - 1.8e-87 293.2 0.0 2.7e-87 292.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 EAQ83890.1 - 3e-66 222.7 0.1 6e-66 221.8 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_1 PF04997.12 EAQ83890.1 - 1.5e-31 109.9 0.0 2.1e-30 106.2 0.0 2.7 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_3 PF04983.18 EAQ83890.1 - 2.5e-21 76.3 0.0 5.4e-21 75.2 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 EAQ83890.1 - 5.4e-18 64.9 0.0 2e-17 63.1 0.0 2.1 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 BUD22 PF09073.10 EAQ83890.1 - 1.8 7.8 14.3 4 6.7 14.3 1.5 1 0 0 1 1 1 0 BUD22 DSBA PF01323.20 EAQ83891.1 - 4.2e-11 43.0 0.0 5.5e-11 42.6 0.0 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Histone PF00125.24 EAQ83892.1 - 1.6e-51 174.1 2.5 1.8e-51 173.9 2.5 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 EAQ83892.1 - 8.4e-06 26.1 0.0 1.3e-05 25.5 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein PAF PF15715.5 EAQ83892.1 - 3.4e-05 24.5 1.0 3.9e-05 24.3 1.0 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-T_C PF15511.6 EAQ83892.1 - 3.6e-05 23.8 0.4 6.4e-05 23.0 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 EAQ83892.1 - 0.0035 17.6 0.3 0.0065 16.7 0.0 1.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 EAQ83892.1 - 0.028 14.5 0.2 0.046 13.8 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 EAQ83892.1 - 0.057 13.4 0.0 0.097 12.7 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated CENP-T_C PF15511.6 EAQ83894.1 - 1.8e-08 34.5 0.1 2.1e-08 34.2 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 EAQ83894.1 - 3.5e-05 24.2 0.1 4.1e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 EAQ83894.1 - 8.6e-05 22.6 0.1 0.00013 22.1 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 EAQ83894.1 - 0.00023 21.5 0.1 0.00029 21.1 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 EAQ83894.1 - 0.00037 20.7 0.1 0.00065 19.9 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 EAQ83894.1 - 0.0094 16.0 0.0 0.011 15.8 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 EAQ83894.1 - 0.037 14.0 0.0 0.046 13.7 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 EAQ83894.1 - 0.081 12.7 0.2 0.1 12.4 0.2 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) HIGH_NTase1_ass PF16581.5 EAQ83894.1 - 0.1 12.6 0.0 0.12 12.4 0.0 1.1 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region GP40 PF11025.8 EAQ83896.1 - 0.012 15.4 0.1 0.014 15.2 0.1 1.1 1 0 0 1 1 1 0 Glycoprotein GP40 of Cryptosporidium Sugar_tr PF00083.24 EAQ83897.1 - 2.5e-135 451.9 16.7 2.9e-135 451.7 16.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EAQ83897.1 - 6.4e-19 68.1 35.6 1.8e-15 56.7 24.3 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EAQ83897.1 - 0.018 13.9 19.2 0.029 13.2 2.4 3.4 2 1 1 4 4 4 0 MFS_1 like family AA_permease PF00324.21 EAQ83898.1 - 4.4e-103 345.4 41.4 6.5e-52 176.7 27.4 2.0 1 1 1 2 2 2 2 Amino acid permease AA_permease_2 PF13520.6 EAQ83898.1 - 9.6e-25 87.3 47.9 1.6e-14 53.6 30.7 2.0 1 1 1 2 2 2 2 Amino acid permease DDE_1 PF03184.19 EAQ83899.1 - 1.5e-26 93.1 0.0 3.3e-26 92.0 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease ZapB PF06005.12 EAQ83899.1 - 1.6 9.3 4.2 2.1 8.8 1.0 2.9 2 0 0 2 2 2 0 Cell division protein ZapB EPSP_synthase PF00275.20 EAQ83900.1 - 1e-128 429.6 0.1 1.6e-128 429.0 0.1 1.3 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.20 EAQ83900.1 - 1.1e-52 178.8 0.0 8.5e-33 113.6 0.0 2.4 1 1 1 2 2 2 2 3-dehydroquinate synthase DHquinase_I PF01487.15 EAQ83900.1 - 1.4e-46 159.6 0.0 4.9e-45 154.6 0.0 2.4 1 1 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.22 EAQ83900.1 - 2.1e-35 122.2 0.0 1.7e-33 115.9 0.0 2.3 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.11 EAQ83900.1 - 9.2e-25 86.7 0.0 2.4e-24 85.4 0.0 1.8 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 EAQ83900.1 - 8.5e-06 25.4 0.8 2.2e-05 24.1 0.8 1.8 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 EAQ83900.1 - 0.0062 16.6 0.0 0.062 13.4 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase AAA_16 PF13191.6 EAQ83900.1 - 0.057 13.8 0.0 0.28 11.5 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain Fe-ADH_2 PF13685.6 EAQ83900.1 - 0.058 13.1 0.2 4.7 6.8 0.0 2.3 2 0 0 2 2 2 0 Iron-containing alcohol dehydrogenase zf-C2H2 PF00096.26 EAQ83901.1 - 8.8e-09 35.4 17.3 0.0037 17.6 1.9 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EAQ83901.1 - 0.00064 20.3 12.5 1 10.4 0.6 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger RasGAP PF00616.19 EAQ83903.1 - 1.1e-34 120.0 0.2 3.5e-22 79.2 0.0 2.6 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.6 EAQ83903.1 - 2.4e-07 31.0 0.2 6.3e-07 29.6 0.2 1.8 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain XRN_M PF17846.1 EAQ83904.1 - 1.3e-144 482.5 0.7 1e-143 479.5 0.0 2.4 2 1 0 2 2 2 1 Xrn1 helical domain XRN_N PF03159.18 EAQ83904.1 - 1.2e-97 326.1 0.0 1.7e-97 325.6 0.0 1.2 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus zf-CCHC_2 PF13696.6 EAQ83904.1 - 0.15 11.9 2.7 0.42 10.5 2.7 1.8 1 0 0 1 1 1 0 Zinc knuckle Uso1_p115_head PF04869.14 EAQ83905.1 - 3.4e-112 374.6 0.0 6.5e-112 373.7 0.0 1.5 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.13 EAQ83905.1 - 8.6e-13 48.8 48.8 8.6e-13 48.8 48.8 5.0 2 2 1 3 3 3 1 Uso1 / p115 like vesicle tethering protein, C terminal region ATG16 PF08614.11 EAQ83905.1 - 0.0052 17.0 18.1 0.0052 17.0 18.1 3.3 1 1 2 3 3 3 1 Autophagy protein 16 (ATG16) Arm PF00514.23 EAQ83905.1 - 0.13 12.3 0.1 5.6 7.2 0.0 2.8 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat NOA36 PF06524.12 EAQ83905.1 - 0.37 10.1 18.0 0.7 9.2 18.0 1.4 1 0 0 1 1 1 0 NOA36 protein DUF5401 PF17380.2 EAQ83905.1 - 6.8 4.6 50.5 9.7 4.1 50.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) Dicty_REP PF05086.12 EAQ83905.1 - 6.9 4.5 12.8 12 3.7 12.8 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Methyltransf_25 PF13649.6 EAQ83906.1 - 4.3e-13 49.8 0.1 1.7e-12 47.8 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EAQ83906.1 - 6.4e-12 46.0 0.1 2.9e-11 43.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 EAQ83906.1 - 4.5e-10 39.4 0.0 8.5e-10 38.5 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 EAQ83906.1 - 1.2e-08 34.9 0.0 2.4e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EAQ83906.1 - 1.5e-06 28.2 0.0 5.4e-06 26.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.7 EAQ83906.1 - 3.6e-06 27.0 0.0 7.2e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EAQ83906.1 - 1.6e-05 24.6 0.1 2.7e-05 23.8 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 EAQ83906.1 - 0.00013 21.4 0.0 0.00023 20.5 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 EAQ83906.1 - 0.00041 21.0 0.1 0.0019 18.9 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 EAQ83906.1 - 0.0058 16.0 0.0 0.0091 15.4 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 EAQ83906.1 - 0.0066 16.2 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.9 EAQ83906.1 - 0.012 15.4 0.0 0.023 14.4 0.0 1.5 1 0 0 1 1 1 0 Lysine methyltransferase FtsJ PF01728.19 EAQ83906.1 - 0.019 15.1 0.0 0.04 14.0 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_24 PF13578.6 EAQ83906.1 - 0.02 15.9 0.0 0.11 13.6 0.0 2.3 3 0 0 3 3 2 0 Methyltransferase domain Methyltransf_9 PF08003.11 EAQ83906.1 - 0.02 13.8 0.0 0.03 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Met_10 PF02475.16 EAQ83906.1 - 0.043 13.6 0.0 0.073 12.8 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein TehB PF03848.14 EAQ83906.1 - 0.062 12.7 0.3 0.16 11.4 0.3 1.7 1 1 0 1 1 1 0 Tellurite resistance protein TehB OPT PF03169.15 EAQ83907.1 - 2.7e-138 462.3 19.0 3.1e-138 462.1 19.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Cation_ATPase_C PF00689.21 EAQ83907.1 - 0.016 14.9 2.4 0.42 10.3 0.2 2.9 2 0 0 2 2 2 0 Cation transporting ATPase, C-terminus Transgly_assoc PF04226.13 EAQ83907.1 - 0.23 11.7 0.2 0.23 11.7 0.2 3.9 4 1 0 4 4 4 0 Transglycosylase associated protein Rav1p_C PF12234.8 EAQ83908.1 - 1.8e-278 925.3 0.1 7.4e-278 923.3 0.1 1.8 1 1 0 1 1 1 1 RAVE protein 1 C terminal DUF3712 PF12505.8 EAQ83908.1 - 1.8e-10 41.1 0.3 4.9e-09 36.5 0.2 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3712) LEA_2 PF03168.13 EAQ83908.1 - 0.0056 17.2 3.2 6 7.5 0.0 4.3 4 0 0 4 4 4 1 Late embryogenesis abundant protein OTCace PF00185.24 EAQ83909.1 - 4.1e-43 147.2 0.0 5.9e-43 146.7 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.21 EAQ83909.1 - 6.9e-43 146.2 0.2 9.8e-43 145.7 0.2 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain ALS_ss_C PF10369.9 EAQ83910.1 - 1.1e-15 57.6 0.0 1.4e-14 54.0 0.0 2.6 3 0 0 3 3 3 1 Small subunit of acetolactate synthase ACT PF01842.25 EAQ83910.1 - 9.1e-15 54.1 0.2 1.6e-14 53.4 0.2 1.4 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.6 EAQ83910.1 - 9.3e-08 31.8 0.0 1.9e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.6 EAQ83910.1 - 0.13 12.3 0.0 26 4.9 0.0 2.5 2 0 0 2 2 2 0 ACT domain OGFr_III PF04680.13 EAQ83910.1 - 0.2 12.3 0.1 0.2 12.3 0.1 2.1 2 0 0 2 2 2 0 Opioid growth factor receptor repeat DUF974 PF06159.13 EAQ83911.1 - 2.4e-82 276.4 0.0 3.2e-82 276.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF974) KH_1 PF00013.29 EAQ83911.1 - 1.4e-06 28.0 0.3 6.1e-05 22.8 0.1 2.4 2 0 0 2 2 2 1 KH domain DENN PF02141.21 EAQ83912.1 - 2e-57 194.2 0.3 3.5e-57 193.4 0.0 1.6 2 0 0 2 2 2 1 DENN (AEX-3) domain dDENN PF03455.19 EAQ83912.1 - 4.3e-14 52.2 1.1 8.5e-14 51.3 1.1 1.5 1 0 0 1 1 1 1 dDENN domain uDENN PF03456.18 EAQ83912.1 - 6.5e-14 52.4 0.0 1.5e-13 51.3 0.0 1.6 1 0 0 1 1 1 1 uDENN domain C1_1 PF00130.22 EAQ83912.1 - 0.012 15.5 7.9 0.023 14.6 7.9 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 EAQ83912.1 - 0.022 15.1 8.2 0.044 14.1 8.2 1.5 1 0 0 1 1 1 0 C1 domain SPA PF08616.10 EAQ83912.1 - 0.18 11.8 0.0 0.33 10.9 0.0 1.4 1 0 0 1 1 1 0 Stabilization of polarity axis PHD PF00628.29 EAQ83912.1 - 0.37 10.7 7.4 0.78 9.7 7.4 1.6 1 0 0 1 1 1 0 PHD-finger PPI_Ypi1 PF07491.11 EAQ83913.1 - 1.4e-23 82.4 6.5 7.8e-23 80.1 6.5 2.2 1 1 0 1 1 1 1 Protein phosphatase inhibitor CDC45 PF02724.14 EAQ83913.1 - 0.7 8.1 6.0 0.94 7.7 6.0 1.2 1 0 0 1 1 1 0 CDC45-like protein RAP1 PF07218.11 EAQ83913.1 - 9.8 4.3 6.3 11 4.2 6.3 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF726 PF05277.12 EAQ83915.1 - 2.2e-107 358.9 0.0 2.9e-107 358.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Glu-tRNAGln PF02686.15 EAQ83916.1 - 0.18 12.1 0.0 0.79 10.1 0.0 1.9 1 1 0 1 1 1 0 Glu-tRNAGln amidotransferase C subunit DUF4813 PF16072.5 EAQ83916.1 - 2.8 7.5 12.8 6.8 6.3 12.8 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4813) SNAP PF14938.6 EAQ83917.1 - 4.7e-106 354.3 8.5 5.6e-106 354.1 8.5 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_7 PF13176.6 EAQ83917.1 - 2.2e-07 30.4 6.9 0.23 11.6 0.0 5.4 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_12 PF13424.6 EAQ83917.1 - 0.00028 21.1 8.4 0.23 11.8 0.4 3.6 2 1 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 EAQ83917.1 - 0.00036 20.4 10.9 6 7.3 0.3 6.5 3 1 4 7 7 7 1 Tetratricopeptide repeat TPR_6 PF13174.6 EAQ83917.1 - 0.034 14.8 8.2 11 6.9 0.0 5.6 5 2 1 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.6 EAQ83917.1 - 0.1 12.9 5.1 7.8 7.0 0.2 4.2 4 1 1 5 5 5 0 Tetratricopeptide repeat NSF PF02071.20 EAQ83917.1 - 0.11 13.2 15.5 2.4 9.3 1.1 5.8 6 0 0 6 6 6 0 Aromatic-di-Alanine (AdAR) repeat TRAPPC-Trs85 PF12739.7 EAQ83917.1 - 0.16 10.9 2.3 0.59 9.0 2.1 1.9 1 1 0 1 1 1 0 ER-Golgi trafficking TRAPP I complex 85 kDa subunit MIT PF04212.18 EAQ83917.1 - 0.38 10.9 9.0 2 8.5 0.0 4.1 3 1 1 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_10 PF13374.6 EAQ83917.1 - 0.47 10.4 7.4 69 3.5 0.0 4.6 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 EAQ83917.1 - 7.1 7.4 11.4 8.2 7.2 0.8 4.5 3 2 1 4 4 3 0 Tetratricopeptide repeat NUC173 PF08161.12 EAQ83918.1 - 3.8e-81 271.6 0.0 9.9e-77 257.2 0.0 3.4 3 0 0 3 3 3 2 NUC173 domain HEAT PF02985.22 EAQ83918.1 - 0.0043 17.2 0.2 2.8 8.5 0.0 3.9 3 0 0 3 3 3 1 HEAT repeat Thg1 PF04446.12 EAQ83918.1 - 0.028 14.5 0.0 0.071 13.1 0.0 1.6 1 0 0 1 1 1 0 tRNAHis guanylyltransferase HrpB1_HrpK PF09613.10 EAQ83918.1 - 0.061 13.0 0.1 1.6 8.4 0.0 2.9 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) Presenilin PF01080.17 EAQ83919.1 - 2.5 6.8 3.2 3.3 6.4 3.2 1.1 1 0 0 1 1 1 0 Presenilin Pkinase PF00069.25 EAQ83920.1 - 8.6e-54 182.7 0.0 6.9e-53 179.7 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ83920.1 - 1.3e-34 119.6 0.0 2e-34 119.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Yop-YscD_cpl PF16697.5 EAQ83920.1 - 2.9e-05 24.3 0.0 9.2e-05 22.7 0.0 1.8 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Kinase-like PF14531.6 EAQ83920.1 - 4.2e-05 23.0 0.0 7.4e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EAQ83920.1 - 0.00032 20.1 0.0 0.00054 19.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FHA PF00498.26 EAQ83920.1 - 0.0006 20.1 0.1 0.0021 18.4 0.1 1.9 1 0 0 1 1 1 1 FHA domain APH PF01636.23 EAQ83920.1 - 0.00064 19.7 2.3 0.018 15.0 0.0 3.2 2 1 1 3 3 3 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EAQ83920.1 - 0.0024 16.7 0.0 0.0045 15.8 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Amino_oxidase PF01593.24 EAQ83922.1 - 6.7e-25 88.3 0.1 9.8e-25 87.7 0.1 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EAQ83922.1 - 4.3e-11 42.9 0.0 9.8e-11 41.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EAQ83922.1 - 1.2e-06 28.1 0.1 0.00036 19.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EAQ83922.1 - 2e-06 27.9 0.0 0.015 15.3 0.0 2.6 2 0 0 2 2 2 2 FAD-NAD(P)-binding DAO PF01266.24 EAQ83922.1 - 0.0048 16.5 0.8 0.15 11.6 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EAQ83922.1 - 0.0068 15.2 0.1 2.7 6.6 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein FAD_oxidored PF12831.7 EAQ83922.1 - 0.023 14.1 0.0 0.035 13.4 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EAQ83922.1 - 0.1 11.6 0.2 0.17 10.9 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.22 EAQ83922.1 - 0.15 11.1 0.1 0.26 10.3 0.1 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A CtaG_Cox11 PF04442.14 EAQ83923.1 - 1.3e-56 190.8 0.0 1.7e-56 190.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 L51_S25_CI-B8 PF05047.16 EAQ83925.1 - 1.4e-23 82.6 0.0 3.4e-23 81.3 0.0 1.7 2 0 0 2 2 2 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain PMT_4TMC PF16192.5 EAQ83926.1 - 7.1e-65 218.3 14.9 7.1e-65 218.3 14.9 2.0 2 1 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase PMT PF02366.18 EAQ83926.1 - 1.8e-63 214.4 13.9 3.1e-62 210.4 12.0 3.0 2 2 2 4 4 4 2 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.19 EAQ83926.1 - 1.3e-33 116.5 0.5 2e-33 115.8 0.5 1.2 1 0 0 1 1 1 1 MIR domain DUF2976 PF11190.8 EAQ83926.1 - 0.053 13.3 1.6 0.37 10.6 2.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) Ras PF00071.22 EAQ83927.1 - 4.7e-49 166.1 0.0 3.3e-38 130.8 0.0 2.1 2 0 0 2 2 2 2 Ras family Roc PF08477.13 EAQ83927.1 - 2.3e-28 98.8 0.0 1.7e-18 67.0 0.0 2.3 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAQ83927.1 - 2.4e-07 30.4 0.0 9e-07 28.5 0.0 1.9 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EAQ83927.1 - 1.1e-05 25.1 0.0 6.1e-05 22.6 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EAQ83927.1 - 0.00079 18.8 0.0 0.0027 17.1 0.0 1.9 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EAQ83927.1 - 0.001 19.1 0.0 0.018 15.1 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EAQ83927.1 - 0.056 13.3 0.0 0.96 9.3 0.0 2.4 2 1 0 2 2 2 0 RsgA GTPase AAA_22 PF13401.6 EAQ83927.1 - 0.082 13.2 0.1 1.4 9.2 0.0 2.5 3 0 0 3 3 3 0 AAA domain Choline_transpo PF04515.12 EAQ83928.1 - 9.7e-29 100.6 20.1 9.7e-29 100.6 20.1 2.1 1 1 1 2 2 2 1 Plasma-membrane choline transporter WW PF00397.26 EAQ83929.1 - 4.9e-10 39.3 7.9 9.4e-10 38.4 7.9 1.5 1 0 0 1 1 1 1 WW domain CCDC50_N PF15295.6 EAQ83929.1 - 0.41 10.8 1.9 0.61 10.2 1.9 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 50 N-terminus DUF2012 PF09430.10 EAQ83930.1 - 2.6e-21 76.0 0.0 3.7e-21 75.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) Cys_Met_Meta_PP PF01053.20 EAQ83931.1 - 7.9e-151 501.9 0.0 9e-151 501.7 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 EAQ83931.1 - 5.9e-10 39.0 0.5 5.9e-10 39.0 0.5 1.5 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 EAQ83931.1 - 1.2e-08 34.4 0.3 2e-08 33.6 0.3 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 EAQ83931.1 - 1.8e-08 34.0 0.1 4.4e-08 32.7 0.1 1.6 2 0 0 2 2 2 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 EAQ83931.1 - 3.6e-05 23.2 0.0 5.8e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.11 EAQ83931.1 - 0.0013 17.4 0.1 0.0017 16.9 0.1 1.1 1 0 0 1 1 1 1 Methionine gamma-lyase Asparaginase_C PF17763.1 EAQ83931.1 - 0.015 15.6 0.1 0.057 13.7 0.0 2.0 2 0 0 2 2 2 0 Glutaminase/Asparaginase C-terminal domain GDC-P PF02347.16 EAQ83931.1 - 0.16 10.8 0.0 0.25 10.1 0.0 1.2 1 0 0 1 1 1 0 Glycine cleavage system P-protein MARVEL PF01284.23 EAQ83932.1 - 9.4e-11 41.9 13.5 1.9e-08 34.5 13.5 2.1 1 1 0 1 1 1 1 Membrane-associating domain DUF2374 PF09574.10 EAQ83932.1 - 4 7.4 6.3 2 8.3 0.1 3.0 4 0 0 4 4 4 0 Protein of unknown function (Duf2374) AMP-binding PF00501.28 EAQ83933.1 - 6.8e-87 291.8 0.0 8.2e-87 291.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme WD40 PF00400.32 EAQ83934.1 - 0.00086 20.1 3.6 1.6 9.7 0.1 3.9 4 0 0 4 4 4 2 WD domain, G-beta repeat CTD_bind PF04818.13 EAQ83935.1 - 4.3e-09 37.0 0.0 8.1e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase II-binding domain. RRM_1 PF00076.22 EAQ83935.1 - 2.9e-07 30.2 0.1 5.1e-07 29.4 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Citrate_synt PF00285.21 EAQ83936.1 - 2.4e-102 342.7 0.0 3.1e-102 342.3 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Eclosion PF04736.12 EAQ83936.1 - 0.029 14.1 0.0 0.071 12.8 0.0 1.6 1 0 0 1 1 1 0 Eclosion hormone Mito_carr PF00153.27 EAQ83937.1 - 5.2e-25 87.2 2.3 3.8e-12 45.9 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein E1-E2_ATPase PF00122.20 EAQ83939.1 - 2.2e-47 160.9 5.0 2.2e-47 160.9 5.0 2.9 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 EAQ83939.1 - 7.2e-18 65.6 0.0 1.7e-17 64.4 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EAQ83939.1 - 2.1e-10 40.1 0.0 4.5e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EAQ83939.1 - 0.0022 17.8 0.1 0.0046 16.7 0.1 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EAQ83939.1 - 0.0074 16.4 0.0 0.015 15.3 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) DUF2613 PF11021.8 EAQ83939.1 - 7.7 6.7 7.6 30 4.8 0.3 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) Chorion_2 PF03964.15 EAQ83940.1 - 0.078 13.8 1.8 0.26 12.2 1.8 1.9 1 0 0 1 1 1 0 Chorion family 2 Nic96 PF04097.14 EAQ83941.1 - 7.4e-225 748.1 0.0 1e-224 747.6 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 bZIP_1 PF00170.21 EAQ83941.1 - 1.4 9.1 7.3 4.5 7.4 7.3 1.9 1 0 0 1 1 1 0 bZIP transcription factor FGGY_C PF02782.16 EAQ83942.1 - 1.4e-51 175.1 0.3 2e-51 174.6 0.3 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 EAQ83942.1 - 2.5e-18 66.5 0.2 1.4e-15 57.5 0.0 2.9 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain Hexokinase_1 PF00349.21 EAQ83942.1 - 0.033 14.1 0.0 0.061 13.2 0.0 1.4 1 0 0 1 1 1 0 Hexokinase BcrAD_BadFG PF01869.20 EAQ83942.1 - 0.054 13.0 0.3 0.46 9.9 0.0 2.1 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family MltA PF03562.17 EAQ83943.1 - 0.47 10.2 2.1 3.6 7.3 0.2 2.3 2 1 0 3 3 3 0 MltA specific insert domain SMN PF06003.12 EAQ83943.1 - 1.7 7.9 7.7 7.4 5.7 0.0 3.3 2 1 1 3 3 3 0 Survival motor neuron protein (SMN) Cu_bind_like PF02298.17 EAQ83944.1 - 0.055 13.5 0.1 0.19 11.7 0.1 1.8 1 1 0 1 1 1 0 Plastocyanin-like domain 4F5 PF04419.14 EAQ83945.1 - 5.7e-10 39.9 12.8 5.7e-10 39.9 12.8 2.5 2 1 1 3 3 3 1 4F5 protein family DFRP_C PF16543.5 EAQ83945.1 - 0.14 12.7 4.2 0.23 12.0 4.2 1.3 1 0 0 1 1 1 0 DRG Family Regulatory Proteins, Tma46 PRIMA1 PF16101.5 EAQ83945.1 - 0.39 10.8 4.7 0.4 10.7 4.1 1.4 1 1 0 1 1 1 0 Proline-rich membrane anchor 1 CFIA_Pcf11 PF11526.8 EAQ83948.1 - 2.9e-17 62.9 0.1 5.1e-17 62.1 0.1 1.4 1 0 0 1 1 1 1 Subunit of cleavage factor IA Pcf11 Myosin_head PF00063.21 EAQ83948.1 - 7e-06 24.5 0.0 9.8e-06 24.1 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) CTD_bind PF04818.13 EAQ83948.1 - 1.4e-05 25.9 0.0 2.9e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase II-binding domain. zf-C2H2_4 PF13894.6 EAQ83948.1 - 0.008 16.9 1.1 0.96 10.5 0.3 3.1 3 0 0 3 3 3 1 C2H2-type zinc finger zf_UBZ PF18439.1 EAQ83948.1 - 1.3 8.7 6.9 1.2 8.8 2.2 2.7 2 1 0 2 2 2 0 Ubiquitin-Binding Zinc Finger GFO_IDH_MocA PF01408.22 EAQ83949.1 - 3e-18 66.8 0.3 5.7e-18 65.9 0.3 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 EAQ83949.1 - 0.0069 17.0 0.3 0.011 16.3 0.3 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Methyltransf_11 PF08241.12 EAQ83950.1 - 5e-10 39.9 0.1 1.2e-09 38.6 0.1 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAQ83950.1 - 1e-08 35.7 0.6 3.1e-07 31.0 0.6 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EAQ83950.1 - 0.00011 22.9 0.0 0.00039 21.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EAQ83950.1 - 0.00023 21.0 0.0 0.00047 20.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAQ83950.1 - 0.00065 19.5 0.1 0.011 15.6 0.1 2.2 2 0 0 2 2 2 1 Methyltransferase domain Myb_DNA-binding PF00249.31 EAQ83951.1 - 7.8e-13 48.4 3.4 1.8e-09 37.6 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAQ83951.1 - 8.7e-05 22.7 3.0 0.063 13.5 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain CAP_GLY PF01302.25 EAQ83953.1 - 1.9e-21 75.8 1.2 2.9e-21 75.2 1.2 1.3 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.6 EAQ83953.1 - 3.7e-19 69.0 0.0 7.6e-19 68.0 0.0 1.5 2 0 0 2 2 2 1 Ubiquitin-like domain ubiquitin PF00240.23 EAQ83953.1 - 0.0015 18.2 0.0 0.0082 15.9 0.0 2.0 1 1 1 2 2 2 1 Ubiquitin family T6_Ig_like PF18002.1 EAQ83953.1 - 0.073 12.9 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 T6 antigen Ig like domain zf-RING_2 PF13639.6 EAQ83954.1 - 2.8e-12 46.8 5.1 4.3e-12 46.2 5.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 EAQ83954.1 - 2.6e-10 39.8 1.9 5.1e-10 38.9 1.9 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 EAQ83954.1 - 4e-07 29.8 3.1 6.6e-07 29.1 3.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EAQ83954.1 - 9.5e-07 28.6 4.5 1.6e-06 27.9 4.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EAQ83954.1 - 5.9e-06 26.5 5.0 1.6e-05 25.1 5.0 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 EAQ83954.1 - 3.5e-05 23.7 1.3 5.8e-05 23.0 1.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EAQ83954.1 - 0.00011 22.0 4.9 0.00019 21.3 4.9 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 EAQ83954.1 - 0.003 17.6 3.6 0.0032 17.5 2.3 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 EAQ83954.1 - 0.008 16.2 1.1 0.015 15.3 1.1 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 EAQ83954.1 - 0.019 14.8 1.6 0.035 14.0 1.6 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.11 EAQ83954.1 - 0.16 12.3 1.0 0.28 11.5 1.0 1.4 1 0 0 1 1 1 0 RING-like domain zf-RING_4 PF14570.6 EAQ83954.1 - 0.35 10.7 2.9 0.61 9.9 2.9 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain CTU2 PF10288.9 EAQ83954.1 - 3.8 7.8 6.0 47 4.3 6.0 2.6 1 1 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 Glyco_hydro_cc PF11790.8 EAQ83955.1 - 3.9e-62 209.9 0.1 5.5e-62 209.5 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core FixS PF03597.15 EAQ83955.1 - 0.59 9.9 3.2 0.41 10.4 0.5 1.9 2 0 0 2 2 2 0 Cytochrome oxidase maturation protein cbb3-type DUF2367 PF10164.9 EAQ83955.1 - 3.9 8.0 0.0 3.9 8.0 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2367) Amidoligase_2 PF12224.8 EAQ83956.1 - 3.3e-14 53.2 0.0 6.5e-14 52.2 0.0 1.6 1 1 0 1 1 1 1 Putative amidoligase enzyme DUF643 PF04867.12 EAQ83956.1 - 0.0091 16.6 0.1 0.017 15.7 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF643) Zn_clus PF00172.18 EAQ83958.1 - 3.8e-08 33.3 9.4 7.2e-08 32.4 9.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EAQ83958.1 - 0.0016 17.4 0.1 0.0025 16.7 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain 6PF2K PF01591.18 EAQ83960.1 - 3.9e-70 235.7 0.0 8.4e-50 169.1 0.0 2.3 2 0 0 2 2 2 2 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 EAQ83960.1 - 4.1e-30 104.9 0.0 3.4e-25 88.9 0.0 2.4 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 EAQ83960.1 - 0.00035 20.7 0.1 0.0028 17.8 0.1 2.2 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.10 EAQ83960.1 - 0.037 13.5 0.0 0.068 12.6 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 PhoU PF01895.19 EAQ83960.1 - 0.11 13.0 0.6 0.29 11.6 0.1 2.0 2 0 0 2 2 2 0 PhoU domain CARD PF00619.21 EAQ83960.1 - 0.13 12.3 0.1 0.3 11.2 0.1 1.5 1 0 0 1 1 1 0 Caspase recruitment domain Sigma70_r4_2 PF08281.12 EAQ83960.1 - 0.17 11.6 0.2 2.5 7.8 0.1 2.4 2 0 0 2 2 2 0 Sigma-70, region 4 dCMP_cyt_deam_1 PF00383.23 EAQ83961.1 - 1.8e-10 40.6 0.2 3.5e-10 39.7 0.2 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EAQ83961.1 - 0.00016 21.5 0.0 0.00032 20.4 0.0 1.4 1 0 0 1 1 1 1 MafB19-like deaminase Na_H_Exchanger PF00999.21 EAQ83962.1 - 4.1e-34 118.0 12.9 4.9e-34 117.7 12.9 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF3272 PF11676.8 EAQ83962.1 - 0.095 13.0 0.0 0.23 11.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3272) Ank_5 PF13857.6 EAQ83963.1 - 7.1e-13 48.5 0.1 3.1e-10 40.1 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EAQ83963.1 - 1.4e-12 47.5 0.8 2.1e-07 31.1 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 EAQ83963.1 - 1.3e-11 44.7 0.3 1.4e-06 28.8 0.1 2.7 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAQ83963.1 - 1.5e-11 44.7 0.0 3.4e-11 43.6 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAQ83963.1 - 4.1e-09 35.9 0.1 0.00015 21.9 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat TIG PF01833.24 EAQ83963.1 - 5.4e-08 32.8 0.0 1.7e-07 31.2 0.0 1.9 1 0 0 1 1 1 1 IPT/TIG domain Peptidase_C97 PF05903.14 EAQ83965.1 - 4.1e-05 23.5 0.0 6.6e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain DUF778 PF05608.12 EAQ83965.1 - 0.011 16.1 0.2 0.022 15.1 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF778) DUF4105 PF13387.6 EAQ83965.1 - 0.011 15.3 0.1 0.017 14.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4105) LRAT PF04970.13 EAQ83965.1 - 0.029 14.7 1.2 0.24 11.7 0.2 2.3 1 1 0 2 2 2 0 Lecithin retinol acyltransferase Velvet PF11754.8 EAQ83966.1 - 1.5e-51 175.7 0.1 7.2e-33 114.6 0.0 3.4 2 2 1 3 3 3 2 Velvet factor VTC PF09359.10 EAQ83968.1 - 1.4e-92 310.0 1.5 2.2e-92 309.4 1.5 1.3 1 0 0 1 1 1 1 VTC domain Mito_carr PF00153.27 EAQ83968.1 - 7e-47 157.3 0.4 3.4e-19 68.6 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein SPX PF03105.19 EAQ83968.1 - 3.5e-08 33.8 22.3 8.3e-05 22.7 0.0 4.3 2 1 1 4 4 4 2 SPX domain FlxA PF14282.6 EAQ83968.1 - 0.029 14.4 0.4 0.068 13.2 0.4 1.5 1 0 0 1 1 1 0 FlxA-like protein DUF2730 PF10805.8 EAQ83968.1 - 0.23 11.5 0.2 0.71 10.0 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) SlyX PF04102.12 EAQ83968.1 - 0.88 10.2 2.7 3.8 8.2 0.1 2.8 2 0 0 2 2 2 0 SlyX zf-RVT PF13966.6 EAQ83969.1 - 0.079 13.7 0.0 0.22 12.2 0.0 1.7 2 0 0 2 2 2 0 zinc-binding in reverse transcriptase GATase_2 PF00310.21 EAQ83970.1 - 1.6e-182 606.9 0.0 2.5e-182 606.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 EAQ83970.1 - 3.1e-155 516.9 0.0 4.9e-155 516.2 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase GXGXG PF01493.19 EAQ83970.1 - 9.8e-57 191.6 0.7 2e-56 190.6 0.5 1.6 1 1 0 1 1 1 1 GXGXG motif Glu_syn_central PF04898.14 EAQ83970.1 - 1.3e-52 179.0 0.6 1.1e-51 175.9 0.3 2.3 2 0 0 2 2 2 1 Glutamate synthase central domain Pyr_redox_2 PF07992.14 EAQ83970.1 - 5e-23 81.8 3.0 1.3e-22 80.4 0.3 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 EAQ83970.1 - 3.1e-21 75.3 0.1 6.6e-21 74.2 0.1 1.6 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster NAD_binding_8 PF13450.6 EAQ83970.1 - 9e-08 32.2 0.1 3.2e-07 30.5 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EAQ83970.1 - 4.7e-07 29.7 3.7 0.0017 18.0 0.4 2.8 3 0 0 3 3 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 EAQ83970.1 - 1.7e-06 28.5 2.6 0.00033 21.1 0.1 3.3 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 EAQ83970.1 - 1.4e-05 24.6 0.1 2.5e-05 23.8 0.1 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase HI0933_like PF03486.14 EAQ83970.1 - 7.4e-05 21.6 0.4 0.00016 20.5 0.4 1.5 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.6 EAQ83970.1 - 0.00011 21.6 0.5 0.055 12.7 0.0 3.5 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EAQ83970.1 - 0.00032 19.9 1.0 0.00062 18.9 0.1 1.9 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 EAQ83970.1 - 0.0009 18.7 0.2 0.0018 17.7 0.2 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EAQ83970.1 - 0.0022 17.3 0.1 0.0022 17.3 0.1 1.8 2 0 0 2 2 2 1 FAD binding domain NAD_binding_7 PF13241.6 EAQ83970.1 - 0.004 17.6 1.9 1.8 9.0 0.1 3.2 3 0 0 3 3 2 1 Putative NAD(P)-binding Thi4 PF01946.17 EAQ83970.1 - 0.0072 15.6 0.3 0.034 13.4 0.1 2.1 2 0 0 2 2 2 1 Thi4 family AlaDh_PNT_C PF01262.21 EAQ83970.1 - 0.0092 15.3 1.3 0.5 9.6 0.1 2.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_Gly3P_dh_N PF01210.23 EAQ83970.1 - 0.015 15.3 0.2 0.05 13.6 0.0 2.0 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 2-Hacid_dh_C PF02826.19 EAQ83970.1 - 0.016 14.6 0.1 0.19 11.1 0.0 2.6 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FMO-like PF00743.19 EAQ83970.1 - 0.03 12.8 0.1 6.8 5.0 0.0 2.7 2 1 0 3 3 3 0 Flavin-binding monooxygenase-like FMN_dh PF01070.18 EAQ83970.1 - 0.03 13.4 0.8 0.094 11.7 0.8 1.8 1 0 0 1 1 1 0 FMN-dependent dehydrogenase AdoHcyase_NAD PF00670.21 EAQ83970.1 - 0.12 12.5 3.1 3.9 7.5 0.0 2.9 3 0 0 3 3 3 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Lycopene_cycl PF05834.12 EAQ83970.1 - 0.23 10.5 0.6 0.73 8.8 0.2 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein GIDA PF01134.22 EAQ83970.1 - 4 6.4 6.0 0.27 10.3 0.1 2.0 3 0 0 3 3 2 0 Glucose inhibited division protein A Apc15p PF05841.11 EAQ83971.1 - 1e-30 107.1 0.6 1e-30 107.1 0.6 2.0 2 0 0 2 2 2 1 Apc15p protein BUD22 PF09073.10 EAQ83971.1 - 0.024 14.0 16.1 0.037 13.4 16.1 1.3 1 0 0 1 1 1 0 BUD22 Myc_N PF01056.18 EAQ83971.1 - 0.16 11.8 11.0 0.18 11.7 10.1 1.5 1 1 0 1 1 1 0 Myc amino-terminal region Drc1-Sld2 PF11719.8 EAQ83971.1 - 1.1 8.7 12.4 1.5 8.2 12.4 1.2 1 0 0 1 1 1 0 DNA replication and checkpoint protein Slu7 PF11708.8 EAQ83971.1 - 9.7 5.8 19.4 3.4 7.4 16.7 1.6 1 1 0 1 1 1 0 Pre-mRNA splicing Prp18-interacting factor Use1 PF09753.9 EAQ83972.1 - 7.8e-06 25.8 0.0 9.2e-06 25.6 0.0 1.2 1 1 0 1 1 1 1 Membrane fusion protein Use1 Sporozoite_P67 PF05642.11 EAQ83972.1 - 1.8 6.6 9.9 1.9 6.5 9.9 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CHZ PF09649.10 EAQ83973.1 - 8.1e-16 57.2 1.6 3.2e-15 55.3 1.6 2.2 1 0 0 1 1 1 1 Histone chaperone domain CHZ Cyclin PF08613.11 EAQ83974.1 - 1.7e-30 106.5 0.0 3.3e-30 105.6 0.0 1.5 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 EAQ83974.1 - 0.00015 21.5 0.0 0.00023 20.9 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Arm PF00514.23 EAQ83975.1 - 5.7e-08 32.5 5.1 1.7 8.8 0.3 8.9 9 1 0 9 9 9 2 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 EAQ83975.1 - 0.00026 21.4 8.1 1.8 9.2 0.0 8.1 9 0 0 9 9 9 1 HEAT-like repeat PUL PF08324.11 EAQ83975.1 - 0.00094 18.5 0.8 0.73 9.0 0.0 3.8 5 0 0 5 5 5 2 PUL domain V-ATPase_H_C PF11698.8 EAQ83975.1 - 0.18 11.9 0.0 0.56 10.3 0.0 1.8 1 0 0 1 1 1 0 V-ATPase subunit H HEAT PF02985.22 EAQ83975.1 - 1.2 9.5 10.2 26 5.4 0.0 6.3 7 0 0 7 7 7 0 HEAT repeat Esterase PF00756.20 EAQ83976.1 - 0.049 13.3 0.1 0.049 13.3 0.1 1.1 1 0 0 1 1 1 0 Putative esterase FlhD PF05247.13 EAQ83977.1 - 0.12 12.7 0.0 0.27 11.5 0.0 1.5 1 0 0 1 1 1 0 Flagellar transcriptional activator (FlhD) RRM_1 PF00076.22 EAQ83978.1 - 1.8e-13 50.1 0.0 4.7e-13 48.8 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EAQ83978.1 - 0.0018 17.9 0.0 0.0038 16.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spc7 PF08317.11 EAQ83979.1 - 0.0027 16.6 25.8 0.0027 16.6 25.8 2.5 1 1 1 2 2 2 2 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 EAQ83979.1 - 0.0052 16.9 61.4 0.009 16.1 7.9 4.6 2 1 3 5 5 5 3 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.9 EAQ83979.1 - 0.032 14.3 58.8 0.25 11.4 20.5 3.7 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fib_alpha PF08702.10 EAQ83979.1 - 0.96 9.6 30.5 2.8 8.1 10.5 4.2 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family Filament PF00038.21 EAQ83979.1 - 1.2 8.6 52.7 4.5 6.8 25.9 2.2 1 1 1 2 2 2 0 Intermediate filament protein NPV_P10 PF05531.12 EAQ83979.1 - 7.1 7.2 20.3 1.1 9.8 3.0 5.0 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Maf_N PF08383.11 EAQ83980.1 - 0.0077 16.0 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 Maf N-terminal region CHD5 PF04420.14 EAQ83981.1 - 6.2e-65 217.9 3.8 9.1e-65 217.4 3.8 1.2 1 0 0 1 1 1 1 CHD5-like protein PV-1 PF06637.11 EAQ83981.1 - 0.021 13.7 0.0 0.025 13.4 0.0 1.1 1 0 0 1 1 1 0 PV-1 protein (PLVAP) PACT_coil_coil PF10495.9 EAQ83981.1 - 0.12 13.0 2.9 0.15 12.6 2.0 1.6 2 0 0 2 2 2 0 Pericentrin-AKAP-450 domain of centrosomal targeting protein PPTA PF01239.22 EAQ83982.1 - 5.8e-06 25.9 13.7 0.0083 15.8 0.5 4.3 5 0 0 5 5 5 2 Protein prenyltransferase alpha subunit repeat Aa_trans PF01490.18 EAQ83983.1 - 3e-76 256.8 20.8 4.2e-76 256.3 20.8 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Asp PF00026.23 EAQ83983.1 - 4.1e-67 226.8 2.6 5.5e-67 226.4 2.6 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EAQ83983.1 - 9.9e-08 32.4 14.0 1.3e-07 32.0 4.2 3.5 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 EAQ83983.1 - 0.00049 19.9 0.0 0.0011 18.8 0.0 1.6 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Claudin_2 PF13903.6 EAQ83983.1 - 6.7 6.4 10.5 0.69 9.6 4.3 2.5 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Ras PF00071.22 EAQ83984.1 - 5.6e-54 182.1 0.0 6.5e-54 181.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAQ83984.1 - 4.2e-22 78.6 0.0 1.5e-21 76.9 0.0 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAQ83984.1 - 2.1e-06 27.3 0.0 4.4e-06 26.2 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 EAQ83984.1 - 0.00022 20.7 0.0 0.00066 19.2 0.0 1.7 1 1 0 2 2 2 1 Signal recognition particle receptor beta subunit Skp1 PF01466.19 EAQ83984.1 - 0.11 12.6 0.4 16 5.7 0.1 2.4 1 1 1 2 2 2 0 Skp1 family, dimerisation domain KOW PF00467.29 EAQ83985.1 - 0.012 15.6 0.0 0.027 14.4 0.0 1.6 1 0 0 1 1 1 0 KOW motif Lipoprotein_2 PF00921.17 EAQ83985.1 - 0.12 11.9 2.3 0.23 11.0 2.3 1.3 1 0 0 1 1 1 0 Borrelia lipoprotein MRP-S26 PF14943.6 EAQ83985.1 - 7.6 6.4 11.5 0.21 11.5 5.2 1.6 2 0 0 2 2 2 0 Mitochondrial ribosome subunit S26 Nop53 PF07767.11 EAQ83986.1 - 0.0011 18.4 0.4 0.0017 17.9 0.4 1.3 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) AKAP7_NLS PF10469.9 EAQ83987.1 - 1.9e-11 44.3 0.0 2.3e-06 27.6 0.0 2.7 3 0 0 3 3 3 2 AKAP7 2'5' RNA ligase-like domain TMF_TATA_bd PF12325.8 EAQ83987.1 - 0.005 17.1 4.9 0.12 12.5 4.9 2.6 1 1 0 1 1 1 1 TATA element modulatory factor 1 TATA binding Lebercilin PF15619.6 EAQ83987.1 - 0.0064 16.2 0.4 0.0064 16.2 0.4 1.9 2 0 0 2 2 2 1 Ciliary protein causing Leber congenital amaurosis disease PKcGMP_CC PF16808.5 EAQ83987.1 - 0.044 13.6 9.3 0.37 10.7 1.0 2.6 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase FlgM PF04316.13 EAQ83987.1 - 0.24 11.8 1.8 0.43 11.0 0.0 2.4 2 0 0 2 2 2 0 Anti-sigma-28 factor, FlgM SOG2 PF10428.9 EAQ83987.1 - 0.3 10.2 15.4 0.23 10.6 9.6 2.1 2 0 0 2 2 2 0 RAM signalling pathway protein Hpt PF01627.23 EAQ83988.1 - 1e-12 48.1 0.1 2e-12 47.2 0.1 1.5 1 1 0 1 1 1 1 Hpt domain DUF3984 PF13136.6 EAQ83990.1 - 8.2e-34 117.5 20.9 1.4e-33 116.7 19.8 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF3984) IKI3 PF04762.12 EAQ83991.1 - 4.1e-276 918.7 0.0 2.5e-153 512.3 0.0 2.1 1 1 1 2 2 2 2 IKI3 family ANAPC4_WD40 PF12894.7 EAQ83991.1 - 0.0038 17.5 0.5 1.6 9.1 0.0 4.1 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Clathrin PF00637.20 EAQ83991.1 - 0.14 12.1 2.6 8.9 6.2 1.0 2.5 1 1 1 2 2 2 0 Region in Clathrin and VPS OAR PF03826.17 EAQ83991.1 - 0.16 11.8 1.9 0.56 10.1 1.9 2.0 1 0 0 1 1 1 0 OAR domain TPR_1 PF00515.28 EAQ83991.1 - 0.47 10.4 2.3 1.5 8.8 0.6 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 EAQ83991.1 - 0.74 10.1 4.3 1.9 8.8 0.5 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat HSP70 PF00012.20 EAQ83992.1 - 2.6e-09 35.8 0.3 1.9e-08 33.0 0.0 1.9 2 0 0 2 2 2 1 Hsp70 protein FtsA PF14450.6 EAQ83992.1 - 0.0013 19.2 0.0 0.015 15.7 0.0 2.4 2 1 0 2 2 2 1 Cell division protein FtsA Pkinase PF00069.25 EAQ83993.1 - 1.8e-50 171.8 0.0 2.7e-50 171.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ83993.1 - 5.9e-30 104.4 0.0 9.3e-30 103.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EAQ83993.1 - 0.012 14.6 0.0 0.016 14.2 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Pox_ser-thr_kin PF05445.11 EAQ83993.1 - 0.066 12.2 0.0 0.099 11.6 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Stc1 PF12898.7 EAQ83995.1 - 5.4e-16 58.9 4.3 8.5e-16 58.3 4.3 1.3 1 0 0 1 1 1 1 Stc1 domain Sugar_tr PF00083.24 EAQ83997.1 - 8.2e-92 308.4 23.2 9.8e-92 308.2 23.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EAQ83997.1 - 1.6e-18 66.8 35.0 7.1e-18 64.6 23.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily LRS4 PF10422.9 EAQ83998.1 - 0.021 14.4 0.1 0.021 14.4 0.1 2.0 2 0 0 2 2 2 0 Monopolin complex subunit LRS4 DUF3496 PF12001.8 EAQ83998.1 - 0.079 13.3 0.7 0.2 12.0 0.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3496) I_LWEQ PF01608.17 EAQ83998.1 - 1.4 9.1 8.0 2.8 8.2 8.0 1.4 1 0 0 1 1 1 0 I/LWEQ domain BCDHK_Adom3 PF10436.9 EAQ83999.1 - 1.3e-71 239.6 0.0 2e-71 239.1 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 EAQ83999.1 - 4.1e-13 49.8 0.0 8.4e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 EAQ83999.1 - 0.078 12.8 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Pyridoxal_deC PF00282.19 EAQ84000.1 - 1e-16 60.6 0.0 1.5e-16 60.1 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 EAQ84000.1 - 2.6e-05 23.3 0.0 6.4e-05 22.1 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 EAQ84000.1 - 0.0056 16.0 0.0 0.0092 15.3 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Glyco_transf_34 PF05637.12 EAQ84001.1 - 1.7e-67 227.6 0.0 2.1e-67 227.3 0.0 1.0 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.14 EAQ84001.1 - 6.3e-05 22.6 0.0 0.18 11.3 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function, DUF273 RINGv PF12906.7 EAQ84002.1 - 4.4e-09 36.3 4.5 6.9e-09 35.7 0.9 2.2 2 0 0 2 2 2 1 RING-variant domain PHD_4 PF16866.5 EAQ84002.1 - 0.0043 17.1 3.3 0.3 11.2 1.9 2.7 3 0 0 3 3 3 1 PHD-finger zf-Sec23_Sec24 PF04810.15 EAQ84002.1 - 0.046 13.8 0.6 13 5.9 0.0 2.4 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger zf-RING_2 PF13639.6 EAQ84002.1 - 1.4 9.3 6.9 2.1 8.8 2.5 2.2 2 0 0 2 2 2 0 Ring finger domain PHD PF00628.29 EAQ84002.1 - 2.6 8.0 8.0 1.1 9.2 5.1 1.8 2 0 0 2 2 2 0 PHD-finger Proteasome PF00227.26 EAQ84003.1 - 9.4e-52 175.3 0.0 1.5e-27 96.3 0.0 2.1 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.9 EAQ84003.1 - 2.5e-05 23.9 1.3 3.6e-05 23.3 0.2 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Ribonuclease_3 PF00636.26 EAQ84004.1 - 2.3e-29 102.1 0.0 1.5e-19 70.5 0.0 3.0 2 0 0 2 2 2 2 Ribonuclease III domain Dicer_dimer PF03368.14 EAQ84004.1 - 1.6e-21 76.3 0.5 4.4e-21 74.8 0.1 2.0 2 0 0 2 2 2 1 Dicer dimerisation domain Helicase_C PF00271.31 EAQ84004.1 - 1e-17 64.5 0.1 4e-17 62.5 0.0 2.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain Ribonucleas_3_3 PF14622.6 EAQ84004.1 - 7.5e-17 61.7 0.0 1.1e-09 38.6 0.0 2.6 2 0 0 2 2 2 2 Ribonuclease-III-like Rgp1 PF08737.10 EAQ84005.1 - 2.6e-162 540.8 0.0 3.8e-162 540.2 0.0 1.2 1 0 0 1 1 1 1 Rgp1 Arrestin_N PF00339.29 EAQ84005.1 - 0.0032 17.5 0.0 0.014 15.5 0.0 1.9 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 EAQ84005.1 - 0.086 13.3 0.1 0.4 11.1 0.0 2.1 2 0 0 2 2 2 0 Arrestin (or S-antigen), C-terminal domain DUF2436 PF10365.9 EAQ84005.1 - 0.14 11.9 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2436) Spo0M PF07070.11 EAQ84005.1 - 0.17 11.4 0.0 16 4.9 0.0 2.3 2 0 0 2 2 2 0 SpoOM protein SPX PF03105.19 EAQ84005.1 - 0.62 9.9 5.1 0.52 10.2 1.4 2.3 2 0 0 2 2 2 0 SPX domain LicD PF04991.13 EAQ84006.1 - 5.1e-23 82.4 0.1 4.3e-15 56.5 0.1 2.6 1 1 1 2 2 2 2 LicD family Arfaptin PF06456.13 EAQ84007.1 - 0.0097 15.5 6.0 0.017 14.7 6.0 1.3 1 0 0 1 1 1 1 Arfaptin-like domain Prominin PF05478.11 EAQ84007.1 - 0.033 12.2 6.6 0.048 11.6 6.6 1.2 1 0 0 1 1 1 0 Prominin IFT57 PF10498.9 EAQ84007.1 - 0.073 12.0 8.5 0.13 11.2 8.5 1.3 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Sec34 PF04136.15 EAQ84007.1 - 0.13 12.1 5.5 0.28 11.1 5.5 1.5 1 0 0 1 1 1 0 Sec34-like family EzrA PF06160.12 EAQ84007.1 - 0.4 8.8 5.2 0.58 8.3 5.2 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA ATP-synt_B PF00430.18 EAQ84007.1 - 0.7 10.0 37.8 0.68 10.0 19.0 2.5 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) TFIIA PF03153.13 EAQ84007.1 - 0.97 9.4 24.6 0.046 13.7 18.8 1.7 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Gram_pos_anchor PF00746.21 EAQ84007.1 - 1.2 9.1 6.0 3.1 7.8 0.3 2.7 2 0 0 2 2 2 0 LPXTG cell wall anchor motif FH2 PF02181.23 EAQ84007.1 - 1.2 8.1 9.8 0.54 9.3 7.4 1.5 1 1 1 2 2 2 0 Formin Homology 2 Domain Matrilin_ccoil PF10393.9 EAQ84007.1 - 1.2 9.0 11.9 3.6 7.5 4.0 3.0 3 1 0 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin DUF3584 PF12128.8 EAQ84007.1 - 1.3 6.5 29.3 1.7 6.0 29.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF572 PF04502.13 EAQ84007.1 - 1.4 8.5 11.8 1.8 8.1 11.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) GAS PF13851.6 EAQ84007.1 - 2.2 7.6 13.5 5 6.4 13.4 1.7 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding T2SSF PF00482.23 EAQ84007.1 - 2.3 8.2 19.0 4.7 7.2 4.4 2.3 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F YabA PF06156.13 EAQ84007.1 - 2.4 8.8 4.6 6.4 7.5 4.6 1.6 1 0 0 1 1 1 0 Initiation control protein YabA DUF2130 PF09903.9 EAQ84007.1 - 3.6 6.8 6.0 0.45 9.7 1.8 1.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2130) ISG65-75 PF11727.8 EAQ84007.1 - 4.6 6.4 18.6 0.66 9.2 7.2 2.1 1 1 0 2 2 2 0 Invariant surface glycoprotein LMBR1 PF04791.16 EAQ84007.1 - 5.4 5.8 6.3 8 5.2 6.3 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF1664 PF07889.12 EAQ84007.1 - 8.3 6.5 9.4 5.3 7.1 7.0 1.9 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) TMPIT PF07851.13 EAQ84007.1 - 9.4 5.4 16.3 1.2 8.3 9.9 1.9 1 1 1 2 2 2 0 TMPIT-like protein ER_lumen_recept PF00810.18 EAQ84008.1 - 1.1e-53 182.1 7.7 1.1e-53 182.1 7.7 1.5 2 0 0 2 2 2 1 ER lumen protein retaining receptor PQ-loop PF04193.14 EAQ84008.1 - 0.00069 19.3 6.7 0.048 13.4 0.2 3.6 3 1 1 4 4 4 2 PQ loop repeat DNA_pol3_delta2 PF13177.6 EAQ84009.1 - 2.5e-11 43.6 0.0 5.1e-11 42.6 0.0 1.5 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA_22 PF13401.6 EAQ84009.1 - 1.1e-06 29.0 0.1 1.7e-05 25.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 EAQ84009.1 - 1.6e-06 28.6 0.0 3.7e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 EAQ84009.1 - 6e-05 23.4 0.3 0.00018 21.8 0.0 2.0 2 0 0 2 2 2 1 Replication factor C C-terminal domain AAA_16 PF13191.6 EAQ84009.1 - 7.8e-05 23.1 1.3 0.0036 17.7 0.4 2.9 2 2 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.6 EAQ84009.1 - 0.00045 20.0 0.2 0.0014 18.4 0.2 1.8 1 1 0 1 1 1 1 AAA domain Rad17 PF03215.15 EAQ84009.1 - 0.0041 17.0 0.0 0.007 16.3 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain DNA_pol3_delta PF06144.13 EAQ84009.1 - 0.016 15.0 0.0 0.031 14.0 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase III, delta subunit Resolvase PF00239.21 EAQ84009.1 - 0.053 13.6 0.2 1.4 9.0 0.3 2.6 2 1 0 2 2 2 0 Resolvase, N terminal domain T4SS-DNA_transf PF02534.14 EAQ84009.1 - 0.073 11.9 0.1 0.17 10.6 0.0 1.6 2 0 0 2 2 2 0 Type IV secretory system Conjugative DNA transfer AAA_5 PF07728.14 EAQ84009.1 - 0.14 12.2 0.4 0.57 10.2 0.4 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 EAQ84009.1 - 0.17 12.4 0.1 0.35 11.4 0.1 1.7 1 1 0 1 1 1 0 ABC transporter Ribosomal_L16 PF00252.18 EAQ84010.1 - 2.8e-34 118.0 0.5 3.9e-34 117.5 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e RFC1 PF08519.12 EAQ84011.1 - 1.7e-60 203.7 0.0 7.3e-60 201.7 0.0 2.0 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain BRCT PF00533.26 EAQ84011.1 - 1.6e-13 50.8 0.0 7.7e-13 48.6 0.0 2.2 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.29 EAQ84011.1 - 2.4e-09 37.7 0.0 6.6e-09 36.3 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 EAQ84011.1 - 1.2e-07 31.8 0.0 2.8e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 Rad17 P-loop domain DNA_pol3_delta PF06144.13 EAQ84011.1 - 3.4e-05 23.7 0.0 7.9e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_22 PF13401.6 EAQ84011.1 - 0.0015 18.8 0.0 0.0056 17.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EAQ84011.1 - 0.0019 18.6 1.6 0.0058 17.0 0.0 2.6 2 2 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 EAQ84011.1 - 0.0043 17.6 0.0 0.015 15.8 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 EAQ84011.1 - 0.023 14.7 0.0 0.054 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EAQ84011.1 - 0.027 14.7 0.0 0.089 13.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EAQ84011.1 - 0.028 14.4 0.0 0.075 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 EAQ84011.1 - 0.058 13.6 4.0 0.13 12.5 0.0 2.8 3 0 0 3 3 3 0 AAA domain NTPase_1 PF03266.15 EAQ84011.1 - 0.062 13.2 0.0 0.22 11.4 0.0 1.9 2 0 0 2 2 2 0 NTPase RuvB_N PF05496.12 EAQ84011.1 - 0.084 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain NACHT PF05729.12 EAQ84011.1 - 0.094 12.6 0.0 0.76 9.7 0.0 2.2 1 1 0 1 1 1 0 NACHT domain GrpE PF01025.19 EAQ84012.1 - 1.9e-36 125.3 6.3 2.4e-36 124.9 6.3 1.1 1 0 0 1 1 1 1 GrpE RNA_pol_A_bac PF01000.26 EAQ84013.1 - 1.1e-30 106.2 0.0 1.8e-30 105.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 EAQ84013.1 - 9.9e-19 66.6 0.0 1.3e-18 66.2 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Mito_carr PF00153.27 EAQ84014.1 - 1.6e-28 98.4 0.0 2.7e-14 52.9 0.1 2.9 3 0 0 3 3 3 2 Mitochondrial carrier protein FDX-ACB PF03147.14 EAQ84015.1 - 6.8e-26 90.5 0.0 1.2e-25 89.8 0.0 1.4 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain tRNA-synt_2d PF01409.20 EAQ84015.1 - 5.3e-20 71.9 0.1 9.1e-10 38.4 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Calcipressin PF04847.12 EAQ84016.1 - 3.4e-49 167.1 0.1 4.4e-49 166.7 0.1 1.1 1 0 0 1 1 1 1 Calcipressin DED PF01335.21 EAQ84016.1 - 0.14 12.5 0.0 0.28 11.5 0.0 1.4 1 0 0 1 1 1 0 Death effector domain Neugrin PF06413.11 EAQ84017.1 - 2.5e-11 44.0 0.8 4.1e-11 43.3 0.8 1.3 1 0 0 1 1 1 1 Neugrin MRP-L20 PF12824.7 EAQ84017.1 - 2.9e-05 24.3 5.8 2.9e-05 24.3 5.8 2.0 2 1 0 2 2 2 1 Mitochondrial ribosomal protein subunit L20 HTH_11 PF08279.12 EAQ84017.1 - 0.042 13.8 0.0 0.073 13.0 0.0 1.3 1 0 0 1 1 1 0 HTH domain Sigma70_r4 PF04545.16 EAQ84017.1 - 0.08 12.5 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 Peptidase_M78 PF06114.13 EAQ84017.1 - 0.15 12.0 0.0 0.33 10.9 0.0 1.6 1 0 0 1 1 1 0 IrrE N-terminal-like domain WD40 PF00400.32 EAQ84018.1 - 3.7e-12 46.6 3.9 0.0093 16.8 0.0 7.3 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAQ84018.1 - 0.00024 21.3 0.1 5.6 7.3 0.0 5.0 3 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain FoP_duplication PF13865.6 EAQ84018.1 - 0.05 14.1 14.0 1.3 9.6 2.7 2.9 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 WD40_like PF17005.5 EAQ84018.1 - 0.082 12.2 0.2 1.6 8.0 0.1 2.4 3 0 0 3 3 3 0 WD40-like domain VID27 PF08553.10 EAQ84018.1 - 0.089 11.8 0.1 3.5 6.6 0.0 2.6 2 0 0 2 2 2 0 VID27 C-terminal WD40-like domain WLM PF08325.10 EAQ84019.1 - 8.6e-45 153.2 0.0 1.2e-44 152.7 0.0 1.2 1 0 0 1 1 1 1 WLM domain DUF45 PF01863.17 EAQ84019.1 - 0.00015 21.9 1.5 0.00029 20.9 1.5 1.4 1 0 0 1 1 1 1 Protein of unknown function DUF45 SprT-like PF10263.9 EAQ84019.1 - 0.024 14.5 0.2 0.039 13.8 0.2 1.5 1 0 0 1 1 1 0 SprT-like family Reprolysin_5 PF13688.6 EAQ84019.1 - 0.068 13.3 0.5 0.12 12.5 0.5 1.5 1 1 0 1 1 1 0 Metallo-peptidase family M12 Glyco_hydro_72 PF03198.14 EAQ84020.1 - 7.1e-117 390.2 0.3 8.6e-117 389.9 0.3 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 EAQ84020.1 - 0.0039 16.7 0.0 0.023 14.1 0.0 2.0 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Citrate_bind PF16114.5 EAQ84021.1 - 9.1e-88 292.4 0.1 1.3e-87 291.9 0.1 1.2 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding ATP-grasp_2 PF08442.10 EAQ84021.1 - 6.8e-06 25.8 0.0 1.6e-05 24.6 0.0 1.7 1 1 0 1 1 1 1 ATP-grasp domain Reovirus_M2 PF05993.12 EAQ84021.1 - 0.0038 15.4 0.1 0.0054 14.9 0.1 1.1 1 0 0 1 1 1 1 Reovirus major virion structural protein Mu-1/Mu-1C (M2) Citrate_synt PF00285.21 EAQ84022.1 - 2.4e-20 73.0 0.0 3.5e-17 62.5 0.0 3.0 1 1 1 2 2 2 2 Citrate synthase, C-terminal domain CoA_binding PF02629.19 EAQ84022.1 - 6.6e-19 68.4 0.1 2e-18 66.8 0.0 1.9 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 EAQ84022.1 - 2.2e-15 56.8 0.1 4.8e-15 55.7 0.1 1.5 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 EAQ84022.1 - 2.5e-06 27.3 0.1 0.00014 21.7 0.0 2.3 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain MRG PF05712.13 EAQ84023.1 - 2.9e-37 127.9 0.5 4.7e-37 127.2 0.5 1.3 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.8 EAQ84023.1 - 2.6e-05 24.0 0.8 5e-05 23.1 0.8 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Cnl2_NKP2 PF09447.10 EAQ84024.1 - 6.4e-26 90.3 0.8 1.1e-25 89.5 0.8 1.4 1 0 0 1 1 1 1 Cnl2/NKP2 family protein HIP1_clath_bdg PF16515.5 EAQ84024.1 - 0.16 12.6 4.8 0.27 11.9 4.0 1.7 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Ribosomal_60s PF00428.19 EAQ84025.1 - 7.4 7.2 10.2 38 4.9 0.2 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein AT_hook PF02178.19 EAQ84026.1 - 0.0013 18.4 44.7 0.021 14.7 4.6 4.6 4 0 0 4 4 4 3 AT hook motif TPR_10 PF13374.6 EAQ84027.1 - 6.1e-05 22.8 1.9 7.8e-05 22.4 0.1 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat Ses_B PF17046.5 EAQ84027.1 - 0.00035 20.4 1.6 0.00061 19.7 1.1 1.7 2 0 0 2 2 2 1 SesB domain on fungal death-pathway protein NB-ARC PF00931.22 EAQ84027.1 - 0.00098 18.4 0.0 0.0021 17.3 0.0 1.5 1 1 0 1 1 1 1 NB-ARC domain AAA_25 PF13481.6 EAQ84027.1 - 0.001 18.7 0.0 0.0017 18.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain TPR_12 PF13424.6 EAQ84027.1 - 0.011 16.0 0.1 0.027 14.7 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat NACHT PF05729.12 EAQ84027.1 - 0.042 13.8 0.0 0.084 12.8 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.6 EAQ84027.1 - 0.081 13.3 0.7 0.43 10.9 0.6 2.5 1 1 0 1 1 1 0 AAA ATPase domain tRNA_U5-meth_tr PF05958.11 EAQ84029.1 - 4.6e-08 32.4 0.0 4.3e-07 29.2 0.0 2.4 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase PrmA PF06325.13 EAQ84029.1 - 0.00086 18.8 0.0 0.0015 18.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 EAQ84029.1 - 0.0016 18.3 0.0 0.0031 17.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAQ84029.1 - 0.0027 18.4 0.0 0.0088 16.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain TRM PF02005.16 EAQ84029.1 - 0.13 11.4 0.0 0.47 9.6 0.0 1.8 2 0 0 2 2 2 0 N2,N2-dimethylguanosine tRNA methyltransferase ALG11_N PF15924.5 EAQ84030.1 - 1.8e-83 279.7 0.0 3e-83 279.0 0.0 1.4 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 EAQ84030.1 - 1.4e-20 73.5 0.0 2.3e-20 72.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EAQ84030.1 - 3.1e-11 43.8 0.0 5.8e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EAQ84030.1 - 0.064 13.3 0.1 0.16 11.9 0.1 1.8 1 0 0 1 1 1 0 Glycosyltransferase Family 4 SOG2 PF10428.9 EAQ84031.1 - 7.3 5.7 11.5 8.8 5.4 11.5 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Syntaxin_2 PF14523.6 EAQ84032.1 - 1.1e-27 96.3 4.7 6.3e-27 93.9 1.1 2.4 2 0 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.19 EAQ84032.1 - 5.4e-17 61.5 0.3 1.4e-16 60.2 0.3 1.8 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 EAQ84032.1 - 0.00015 21.5 9.2 0.046 13.4 1.7 2.4 2 0 0 2 2 2 2 Syntaxin Vac_Fusion PF02346.16 EAQ84032.1 - 0.00054 19.5 0.0 0.0017 17.9 0.0 1.8 1 0 0 1 1 1 1 Chordopoxvirus multifunctional envelope protein A27 T3SSipB PF16535.5 EAQ84032.1 - 0.0092 16.5 1.3 0.0092 16.5 1.3 1.9 2 0 0 2 2 2 1 Type III cell invasion protein SipB Synaptobrevin PF00957.21 EAQ84032.1 - 0.027 14.2 0.1 0.087 12.6 0.1 1.9 1 0 0 1 1 1 0 Synaptobrevin DUF883 PF05957.13 EAQ84032.1 - 0.047 14.3 8.2 0.62 10.7 0.1 3.2 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) DUF948 PF06103.11 EAQ84032.1 - 0.057 13.7 1.6 4.1 7.7 0.5 2.7 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) CEP209_CC5 PF16574.5 EAQ84032.1 - 0.062 13.5 6.4 0.26 11.5 0.4 2.3 2 0 0 2 2 2 0 Coiled-coil region of centrosome protein CE290 Nre_C PF04895.12 EAQ84032.1 - 0.072 13.0 0.1 0.072 13.0 0.1 2.1 3 0 0 3 3 3 0 Archaeal Nre, C-terminal DUF2951 PF11166.8 EAQ84032.1 - 0.2 11.9 1.1 1.2 9.4 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) DUF1664 PF07889.12 EAQ84032.1 - 0.21 11.6 3.4 9 6.4 0.5 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF16 PF01519.16 EAQ84032.1 - 1.4 9.4 8.5 0.18 12.3 0.9 2.5 2 1 0 2 2 2 0 Protein of unknown function DUF16 KASH_CCD PF14662.6 EAQ84032.1 - 8 6.2 11.1 11 5.8 3.2 3.1 2 1 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH Ndc1_Nup PF09531.10 EAQ84033.1 - 7.2e-189 629.4 0.0 8.1e-189 629.2 0.0 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup DUF2564 PF10819.8 EAQ84033.1 - 0.081 13.3 1.1 0.27 11.7 1.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2564) DUF4129 PF13559.6 EAQ84034.1 - 7.5e-05 22.9 0.1 0.00017 21.8 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4129) NICE-3 PF07406.11 EAQ84034.1 - 0.0054 16.8 0.3 2.8 7.9 0.0 2.2 2 0 0 2 2 2 2 NICE-3 protein ACC_epsilon PF13822.6 EAQ84035.1 - 1 10.1 0.0 1 10.1 0.0 4.2 4 1 1 5 5 5 0 Acyl-CoA carboxylase epsilon subunit BBP1_N PF15271.6 EAQ84035.1 - 3.5 8.4 11.4 4.7 8.0 7.3 2.6 1 1 1 2 2 2 0 Spindle pole body component BBP1, Mps2-binding protein LTXXQ PF07813.12 EAQ84036.1 - 0.1 13.4 4.3 0.11 13.3 0.3 2.7 2 0 0 2 2 2 0 LTXXQ motif family protein FAD_binding_3 PF01494.19 EAQ84037.1 - 4.6e-73 246.5 0.0 6e-73 246.1 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 EAQ84037.1 - 7.2e-41 140.0 0.1 1.6e-40 138.8 0.0 1.6 2 0 0 2 2 2 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox_2 PF07992.14 EAQ84037.1 - 0.00053 19.3 0.0 0.02 14.2 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EAQ84037.1 - 0.0041 17.6 0.0 0.012 16.1 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 EAQ84037.1 - 0.024 14.2 0.0 0.054 13.1 0.0 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_8 PF13450.6 EAQ84037.1 - 0.028 14.7 0.0 0.066 13.5 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EAQ84037.1 - 0.039 13.5 0.0 0.67 9.5 0.0 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.14 EAQ84037.1 - 0.078 11.7 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.17 EAQ84037.1 - 0.086 12.1 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Thi4 family XdhC_C PF13478.6 EAQ84037.1 - 0.1 13.1 0.0 0.27 11.7 0.0 1.7 1 0 0 1 1 1 0 XdhC Rossmann domain ApbA PF02558.16 EAQ84037.1 - 0.12 12.0 0.0 1.2 8.7 0.0 2.2 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Epimerase PF01370.21 EAQ84037.1 - 0.14 11.6 0.0 4.2 6.8 0.0 2.6 3 0 0 3 3 3 0 NAD dependent epimerase/dehydratase family Fungal_trans PF04082.18 EAQ84038.1 - 1.8e-22 79.7 0.0 4.6e-21 75.0 0.0 2.4 2 0 0 2 2 2 2 Fungal specific transcription factor domain Fungal_trans_2 PF11951.8 EAQ84039.1 - 1.9e-46 158.6 0.0 1.6e-23 83.2 0.0 3.1 2 1 1 3 3 3 3 Fungal specific transcription factor domain Zn_clus PF00172.18 EAQ84039.1 - 3.6e-07 30.2 13.4 6.6e-07 29.4 13.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CYYR1 PF10873.8 EAQ84040.1 - 0.0031 18.0 0.1 0.01 16.3 0.0 1.9 1 1 0 1 1 1 1 Cysteine and tyrosine-rich protein 1 EphA2_TM PF14575.6 EAQ84040.1 - 0.016 16.0 0.1 0.041 14.8 0.1 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4834 PF16118.5 EAQ84040.1 - 0.18 12.8 1.6 0.25 12.3 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Syndecan PF01034.20 EAQ84040.1 - 0.21 11.5 2.5 0.47 10.4 2.5 1.5 1 0 0 1 1 1 0 Syndecan domain Abhydrolase_3 PF07859.13 EAQ84042.1 - 5.5e-32 111.3 0.0 3.6e-21 76.0 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Lipase_3 PF01764.25 EAQ84042.1 - 0.029 14.2 0.0 0.058 13.2 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF2158 PF09926.9 EAQ84047.1 - 0.1 12.4 0.0 0.11 12.3 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized small protein (DUF2158) Fungal_trans PF04082.18 EAQ84048.1 - 5.4e-21 74.8 0.0 1.2e-20 73.7 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EAQ84048.1 - 7.9e-08 32.3 12.7 1.6e-07 31.4 12.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dicty_REP PF05086.12 EAQ84051.1 - 2.9 5.7 3.7 3.4 5.5 3.7 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Pyridoxal_deC PF00282.19 EAQ84052.1 - 1.3e-74 251.2 0.0 1.8e-74 250.8 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain PXT1 PF15214.6 EAQ84052.1 - 0.065 13.6 0.1 0.43 10.9 0.0 2.2 2 0 0 2 2 2 0 Peroxisomal testis-specific protein 1 Drf_GBD PF06371.13 EAQ84052.1 - 0.11 12.0 0.1 6.3 6.3 0.6 2.2 2 0 0 2 2 2 0 Diaphanous GTPase-binding Domain Aminotran_3 PF00202.21 EAQ84053.1 - 3.4e-72 243.3 0.0 6.9e-72 242.3 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-III LPMO_10 PF03067.15 EAQ84054.1 - 0.056 14.1 2.2 0.12 13.0 0.3 2.5 2 1 0 2 2 2 0 Lytic polysaccharide mono-oxygenase, cellulose-degrading AF-4 PF05110.13 EAQ84054.1 - 1.4 6.9 9.0 0.27 9.3 0.9 2.0 2 0 0 2 2 2 0 AF-4 proto-oncoprotein LsmAD PF06741.13 EAQ84056.1 - 1.5e-27 96.0 1.8 1.5e-27 96.0 1.8 2.2 2 0 0 2 2 2 1 LsmAD domain Ebola_NP PF05505.12 EAQ84057.1 - 0.31 9.3 2.6 0.36 9.1 2.6 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein Nucleo_P87 PF07267.11 EAQ84057.1 - 1.1 8.1 4.5 1.3 7.7 4.5 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 AIP3 PF03915.13 EAQ84058.1 - 4e-141 470.8 12.5 5.4e-139 463.8 12.5 2.2 1 1 0 1 1 1 1 Actin interacting protein 3 MIP-T3_C PF17749.1 EAQ84058.1 - 0.14 12.1 8.3 0.47 10.4 6.6 2.6 1 1 1 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region AAA_13 PF13166.6 EAQ84058.1 - 0.18 10.4 2.7 0.35 9.4 2.7 1.4 1 0 0 1 1 1 0 AAA domain DUF1664 PF07889.12 EAQ84058.1 - 0.24 11.4 4.9 4.3 7.4 0.4 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DivIC PF04977.15 EAQ84058.1 - 0.91 9.3 7.1 6.5 6.6 0.4 3.3 3 0 0 3 3 3 0 Septum formation initiator SKA1 PF07160.12 EAQ84058.1 - 1.7 8.4 6.2 16 5.3 0.0 3.1 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 1 NPV_P10 PF05531.12 EAQ84058.1 - 2 8.9 7.1 3 8.4 0.6 3.6 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Wtap PF17098.5 EAQ84058.1 - 2.4 8.1 8.6 0.2 11.6 1.4 2.6 3 0 0 3 3 3 0 WTAP/Mum2p family Beta-lactamase PF00144.24 EAQ84059.1 - 9.4e-37 127.0 0.1 1.4e-36 126.4 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase Myb_DNA-binding PF00249.31 EAQ84061.1 - 4.5e-10 39.6 0.0 0.00011 22.3 0.0 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain DS PF01916.17 EAQ84062.1 - 9.4e-127 422.2 0.0 1.1e-126 421.9 0.0 1.1 1 0 0 1 1 1 1 Deoxyhypusine synthase HMGL-like PF00682.19 EAQ84063.1 - 1.6e-25 90.2 1.2 1.8e-09 37.5 0.1 3.2 2 1 1 3 3 3 3 HMGL-like DDE_3 PF13358.6 EAQ84063.1 - 1.8e-15 56.9 0.1 3.8e-15 55.9 0.1 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease FliS PF02561.14 EAQ84063.1 - 0.12 12.6 0.2 0.62 10.3 0.0 2.1 2 0 0 2 2 2 0 Flagellar protein FliS NACHT PF05729.12 EAQ84065.1 - 4e-05 23.6 0.0 0.00011 22.2 0.0 1.7 1 0 0 1 1 1 1 NACHT domain ANAPC4_WD40 PF12894.7 EAQ84065.1 - 4e-05 23.8 0.0 0.57 10.5 0.0 5.1 4 2 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EAQ84065.1 - 0.0022 18.8 3.2 4.2 8.4 0.0 4.9 5 0 0 5 5 5 1 WD domain, G-beta repeat SOG2 PF10428.9 EAQ84065.1 - 0.022 14.0 21.9 0.049 12.8 21.9 1.5 1 0 0 1 1 1 0 RAM signalling pathway protein RAB3GAP2_N PF14655.6 EAQ84065.1 - 0.1 11.8 0.0 11 5.2 0.0 2.4 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Cytochrom_D1 PF02239.16 EAQ84065.1 - 0.13 10.8 0.0 4.2 5.8 0.0 2.2 2 0 0 2 2 2 0 Cytochrome D1 heme domain DUF573 PF04504.14 EAQ84065.1 - 0.16 12.6 0.0 0.63 10.7 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function, DUF573 Fructosamin_kin PF03881.14 EAQ84066.1 - 6.8e-28 97.7 0.0 9e-28 97.3 0.0 1.1 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 EAQ84066.1 - 2.8e-06 27.4 0.1 5.3e-06 26.5 0.1 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family MFS_1 PF07690.16 EAQ84067.1 - 5.9e-31 107.7 6.8 1e-30 106.9 6.8 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EAQ84067.1 - 4.4e-07 29.1 1.6 6.5e-07 28.6 1.6 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 EAQ84067.1 - 0.00079 18.0 3.8 0.0012 17.4 3.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Chromo PF00385.24 EAQ84068.1 - 2.1e-15 56.3 0.5 3.7e-15 55.5 0.5 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-CCHC PF00098.23 EAQ84069.1 - 9.9e-05 22.2 3.4 9.9e-05 22.2 3.4 3.0 3 0 0 3 3 3 1 Zinc knuckle COG2 PF06148.11 EAQ84069.1 - 0.0048 17.0 3.7 0.0094 16.0 3.7 1.4 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 PspA_IM30 PF04012.12 EAQ84069.1 - 0.0075 15.9 5.9 0.013 15.1 5.9 1.3 1 0 0 1 1 1 1 PspA/IM30 family Spc7 PF08317.11 EAQ84069.1 - 0.0098 14.8 3.5 0.015 14.2 3.5 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF812 PF05667.11 EAQ84069.1 - 0.012 14.5 4.0 0.018 14.0 4.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Golgin_A5 PF09787.9 EAQ84069.1 - 0.021 14.3 4.5 0.035 13.6 4.5 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF148 PF02520.17 EAQ84069.1 - 0.12 12.5 5.6 0.22 11.6 5.6 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF148 Filament PF00038.21 EAQ84069.1 - 0.14 11.7 5.1 0.25 10.9 5.1 1.3 1 0 0 1 1 1 0 Intermediate filament protein Med30 PF11315.8 EAQ84069.1 - 0.16 12.2 3.3 3.8 7.7 0.1 2.3 1 1 1 2 2 2 0 Mediator complex subunit 30 TPR_MLP1_2 PF07926.12 EAQ84069.1 - 0.17 12.0 7.5 0.54 10.3 7.5 1.8 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein HIP1_clath_bdg PF16515.5 EAQ84069.1 - 0.25 12.0 6.3 0.65 10.6 6.3 1.7 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF1664 PF07889.12 EAQ84069.1 - 0.27 11.3 3.5 0.58 10.2 3.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) H-kinase_dim PF02895.14 EAQ84069.1 - 0.35 11.3 2.1 0.88 10.0 2.1 1.6 1 0 0 1 1 1 0 Signal transducing histidine kinase, homodimeric domain CENP-F_leu_zip PF10473.9 EAQ84069.1 - 0.56 10.2 7.8 2.1 8.4 7.8 1.8 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2408 PF10303.9 EAQ84069.1 - 0.73 10.4 4.0 4.3 7.9 4.1 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) SlyX PF04102.12 EAQ84069.1 - 1.5 9.5 5.3 3.3 8.4 5.3 1.6 1 0 0 1 1 1 0 SlyX zf-CCHC_4 PF14392.6 EAQ84069.1 - 8.1 6.3 7.9 1.1 9.0 0.4 2.7 2 0 0 2 2 2 0 Zinc knuckle Putative_PNPOx PF01243.20 EAQ84071.1 - 0.055 13.7 0.0 0.075 13.2 0.0 1.2 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase RAP1 PF07218.11 EAQ84071.1 - 5 5.3 4.7 5.1 5.3 4.7 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Bac_A_amyl_C PF18612.1 EAQ84072.1 - 0.11 12.3 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Bacterial Alpha amylase C-terminal domain NMT1 PF09084.11 EAQ84073.1 - 4.4e-09 36.6 0.0 1.4e-08 34.9 0.0 1.9 1 1 0 1 1 1 1 NMT1/THI5 like NMT1_3 PF16868.5 EAQ84073.1 - 6.1e-05 22.6 0.0 9.3e-05 22.0 0.0 1.4 1 1 0 1 1 1 1 NMT1-like family SBP_bac_3 PF00497.20 EAQ84073.1 - 0.0003 20.3 0.0 0.00047 19.7 0.0 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Phosphonate-bd PF12974.7 EAQ84073.1 - 0.0086 15.7 0.0 0.015 14.9 0.0 1.5 1 1 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein RVT_1 PF00078.27 EAQ84077.1 - 4.2e-38 131.1 0.0 2.8e-37 128.4 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 EAQ84077.1 - 1.8e-07 31.0 0.3 4.8e-07 29.6 0.1 1.9 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase zf-RVT PF13966.6 EAQ84077.1 - 0.058 14.1 0.5 0.47 11.2 0.0 2.7 2 0 0 2 2 2 0 zinc-binding in reverse transcriptase Glyco_transf_90 PF05686.12 EAQ84079.1 - 4.2e-07 29.2 0.0 0.00018 20.6 0.0 2.8 2 1 0 2 2 2 2 Glycosyl transferase family 90 Ank PF00023.30 EAQ84080.1 - 3e-08 33.7 0.2 0.046 14.2 0.0 3.8 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.7 EAQ84080.1 - 3e-07 30.9 0.6 0.00018 22.1 0.1 2.7 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAQ84080.1 - 3.4e-05 23.9 0.1 0.037 14.6 0.0 3.9 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 EAQ84080.1 - 0.0001 22.5 0.4 0.28 11.6 0.1 3.9 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAQ84080.1 - 0.00078 20.0 0.1 0.25 12.0 0.0 3.4 3 1 0 3 3 3 1 Ankyrin repeats (many copies) Esterase_phd PF10503.9 EAQ84081.1 - 2.5e-23 82.7 0.2 3.9e-23 82.1 0.2 1.2 1 0 0 1 1 1 1 Esterase PHB depolymerase CBM_1 PF00734.18 EAQ84081.1 - 6.4e-11 42.0 11.4 6.4e-11 42.0 11.4 2.9 3 0 0 3 3 3 1 Fungal cellulose binding domain Peptidase_S9 PF00326.21 EAQ84081.1 - 4.7e-10 39.3 0.1 8.5e-10 38.5 0.1 1.4 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 EAQ84081.1 - 0.0096 15.7 0.1 0.068 13.0 0.1 2.1 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.20 EAQ84081.1 - 0.031 13.9 0.1 0.045 13.4 0.1 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 EAQ84081.1 - 0.085 12.7 0.0 0.14 12.0 0.0 1.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold DLH PF01738.18 EAQ84081.1 - 0.27 10.7 2.6 0.13 11.8 0.5 1.5 2 0 0 2 2 2 0 Dienelactone hydrolase family SDA1 PF05285.12 EAQ84082.1 - 6.1e-88 295.6 39.8 6.1e-88 295.6 39.8 2.7 2 1 0 2 2 2 1 SDA1 NUC130_3NT PF08158.12 EAQ84082.1 - 2.9e-19 69.1 0.1 7.9e-19 67.7 0.1 1.8 1 0 0 1 1 1 1 NUC130/3NT domain EABR PF12180.8 EAQ84082.1 - 0.0035 16.9 0.4 0.0083 15.7 0.4 1.6 1 0 0 1 1 1 1 TSG101 and ALIX binding domain of CEP55 Dict-STAT-coil PF09267.10 EAQ84082.1 - 0.061 13.7 0.3 0.26 11.7 0.0 2.2 2 0 0 2 2 2 0 Dictyostelium STAT, coiled coil bZIP_1 PF00170.21 EAQ84084.1 - 1.5e-07 31.4 2.8 1.5e-07 31.4 2.8 2.7 2 1 0 2 2 2 1 bZIP transcription factor DUF1980 PF09323.10 EAQ84084.1 - 0.33 10.9 5.2 0.76 9.7 1.5 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF1980) O-antigen_lig PF13425.6 EAQ84084.1 - 2.8 6.6 4.3 4.2 6.1 4.3 1.2 1 0 0 1 1 1 0 O-antigen ligase like membrane protein AAA_30 PF13604.6 EAQ84086.1 - 0.14 11.9 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_12 PF13087.6 EAQ84087.1 - 4.2e-25 88.5 0.0 5.5e-25 88.2 0.0 1.1 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 EAQ84087.1 - 0.00036 20.4 0.1 0.0041 16.9 0.1 2.0 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.6 EAQ84087.1 - 0.02 14.7 0.0 0.035 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Tyrosinase PF00264.20 EAQ84088.1 - 1.3e-24 87.7 5.2 4.8e-24 85.9 5.2 1.9 1 1 0 1 1 1 1 Common central domain of tyrosinase Plk4_PB2 PF18409.1 EAQ84089.1 - 0.13 13.0 1.4 1.8 9.3 0.0 2.9 2 1 2 4 4 4 0 Polo-like Kinase 4 Polo Box 2 YabA PF06156.13 EAQ84089.1 - 0.31 11.7 2.6 19 5.9 0.1 2.6 1 1 1 2 2 2 0 Initiation control protein YabA GCV_T PF01571.21 EAQ84093.1 - 0.0085 15.5 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain SAP PF02037.27 EAQ84094.1 - 2e-08 33.8 0.1 3.7e-08 32.9 0.1 1.4 1 0 0 1 1 1 1 SAP domain FANC_SAP PF18081.1 EAQ84094.1 - 0.01 16.0 0.0 0.041 14.1 0.0 2.0 1 0 0 1 1 1 0 Fanconi anemia-associated nuclease SAP domain Fungal_trans PF04082.18 EAQ84095.1 - 1.1e-21 77.1 0.0 1.8e-21 76.3 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EAQ84095.1 - 0.00013 22.0 7.8 0.00013 22.0 7.8 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Herpes_UL6 PF01763.16 EAQ84097.1 - 0.027 13.0 0.7 0.044 12.3 0.7 1.2 1 0 0 1 1 1 0 Herpesvirus UL6 like AAA_32 PF13654.6 EAQ84097.1 - 0.097 11.4 2.1 0.14 10.9 2.1 1.1 1 0 0 1 1 1 0 AAA domain Elf1 PF05129.13 EAQ84097.1 - 3.4 7.8 8.1 0.61 10.2 3.8 2.0 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like Pneumo_att_G PF05539.11 EAQ84097.1 - 9.9 5.6 13.8 0.21 11.1 0.3 2.3 2 0 0 2 2 2 0 Pneumovirinae attachment membrane glycoprotein G DOCK_N PF16172.5 EAQ84099.1 - 3.7e-124 414.5 0.0 6e-124 413.8 0.0 1.3 1 0 0 1 1 1 1 DOCK N-terminus DOCK-C2 PF14429.6 EAQ84099.1 - 2.3e-35 122.2 0.0 3.8e-35 121.5 0.0 1.4 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins DHR-2 PF06920.13 EAQ84099.1 - 6.3e-30 104.3 0.7 4.6e-29 101.5 0.7 2.0 1 1 0 1 1 1 1 Dock homology region 2 SH3_1 PF00018.28 EAQ84099.1 - 0.0023 17.5 0.0 0.0047 16.5 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EAQ84099.1 - 0.11 12.4 0.0 0.46 10.4 0.0 2.0 2 0 0 2 2 2 0 Variant SH3 domain MLTR_LBD PF17765.1 EAQ84100.1 - 0.089 12.9 0.1 0.38 10.9 0.0 1.9 2 0 0 2 2 2 0 MmyB-like transcription regulator ligand binding domain Chorismate_synt PF01264.21 EAQ84101.1 - 7.4e-139 462.0 0.0 8.5e-139 461.8 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase BPL_LplA_LipB PF03099.19 EAQ84102.1 - 6.1e-05 22.9 0.0 0.0001 22.2 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Clathrin PF00637.20 EAQ84103.1 - 3.6e-21 75.5 4.1 6.1e-20 71.5 1.3 2.8 3 0 0 3 3 3 1 Region in Clathrin and VPS VPS11_C PF12451.8 EAQ84103.1 - 1.6e-19 69.9 0.2 3.8e-19 68.7 0.2 1.7 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal zf-C3HC4_2 PF13923.6 EAQ84103.1 - 1.7e-05 24.5 2.8 4.2e-05 23.3 2.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3H2C3 PF17122.5 EAQ84103.1 - 6e-05 23.0 4.4 6e-05 23.0 4.4 2.2 2 1 0 2 2 2 1 Zinc-finger zf-RING_5 PF14634.6 EAQ84103.1 - 0.00056 19.8 3.5 0.0012 18.7 3.5 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 EAQ84103.1 - 0.0032 17.8 2.9 0.0087 16.4 2.9 1.8 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 EAQ84103.1 - 0.061 13.6 3.0 0.16 12.3 3.0 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EAQ84103.1 - 0.1 12.6 1.6 0.6 10.2 1.9 2.1 1 1 0 1 1 1 0 RING-type zinc-finger zf-ANAPC11 PF12861.7 EAQ84103.1 - 0.12 12.4 1.0 0.35 10.9 1.0 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 EAQ84103.1 - 0.21 11.5 5.9 0.03 14.2 1.7 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) K_channel_TID PF07941.11 EAQ84103.1 - 0.36 11.3 2.4 1 9.8 2.4 1.7 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain Mucin PF01456.17 EAQ84103.1 - 3.5 7.6 13.6 9.9 6.2 13.6 1.7 1 0 0 1 1 1 0 Mucin-like glycoprotein MutL_C PF08676.11 EAQ84104.1 - 2.8e-12 46.6 0.1 2.8e-10 40.1 0.1 2.8 1 1 0 1 1 1 1 MutL C terminal dimerisation domain CN_hydrolase PF00795.22 EAQ84107.1 - 2.1e-25 89.6 0.0 8e-10 38.5 0.2 3.8 2 1 1 3 3 3 3 Carbon-nitrogen hydrolase AA_permease_2 PF13520.6 EAQ84109.1 - 3.4e-32 111.8 38.9 3.2e-31 108.6 38.9 2.4 1 1 0 1 1 1 1 Amino acid permease Kinocilin PF15033.6 EAQ84109.1 - 8.3 6.1 6.2 4.5 6.9 0.3 3.0 3 0 0 3 3 3 0 Kinocilin protein Sortase PF04203.13 EAQ84110.1 - 0.072 12.9 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Sortase domain Phage_lysozyme PF00959.19 EAQ84111.1 - 9.2e-14 51.8 0.0 1.4e-13 51.2 0.0 1.3 1 0 0 1 1 1 1 Phage lysozyme SH3_3 PF08239.11 EAQ84111.1 - 0.00034 20.8 2.0 0.00095 19.4 0.4 2.3 2 0 0 2 2 2 1 Bacterial SH3 domain CHAP PF05257.16 EAQ84112.1 - 1.1e-15 57.9 6.0 1.1e-15 57.9 6.0 2.0 2 1 0 2 2 2 1 CHAP domain SH3_3 PF08239.11 EAQ84112.1 - 0.0012 19.0 1.9 0.0016 18.6 0.3 2.0 2 0 0 2 2 2 1 Bacterial SH3 domain Glyco_transf_15 PF01793.16 EAQ84116.1 - 2e-87 293.5 0.1 1.8e-86 290.3 0.1 2.0 1 1 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase NDC10_II PF16787.5 EAQ84117.1 - 1.1e-19 70.7 0.0 1.5e-19 70.2 0.0 1.1 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 RVT_1 PF00078.27 EAQ84117.1 - 0.0011 18.6 0.0 0.0016 18.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Fungal_trans_2 PF11951.8 EAQ84118.1 - 1e-06 27.9 0.0 1.3e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cytomega_US3 PF05963.11 EAQ84118.1 - 0.14 11.8 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Cytomegalovirus US3 protein adh_short PF00106.25 EAQ84119.1 - 5e-20 71.8 1.1 9.9e-17 61.0 1.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EAQ84119.1 - 2.1e-13 50.4 1.2 1.3e-09 37.9 1.9 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EAQ84119.1 - 5.5e-10 39.4 1.0 9.7e-10 38.6 1.0 1.4 1 0 0 1 1 1 1 KR domain ABC2_membrane PF01061.24 EAQ84120.1 - 1.1e-57 194.9 51.6 9.5e-42 142.8 20.9 3.7 3 1 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 EAQ84120.1 - 2.7e-27 96.0 0.0 1.2e-15 58.2 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 EAQ84120.1 - 2.9e-21 75.2 0.0 2.9e-21 75.2 0.0 2.3 2 0 0 2 2 1 1 CDR ABC transporter ABC2_membrane_3 PF12698.7 EAQ84120.1 - 1.1e-08 34.6 12.7 1.6e-08 34.1 7.1 2.5 2 1 0 2 2 2 1 ABC-2 family transporter protein AAA_16 PF13191.6 EAQ84120.1 - 1.8e-05 25.2 0.1 0.037 14.4 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 EAQ84120.1 - 6.6e-05 22.9 0.0 0.0031 17.4 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_18 PF13238.6 EAQ84120.1 - 0.00019 22.0 0.0 0.013 16.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EAQ84120.1 - 0.0026 18.0 0.0 0.09 13.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 EAQ84120.1 - 0.0047 17.2 0.0 0.081 13.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EAQ84120.1 - 0.023 14.4 0.0 0.11 12.2 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_30 PF13604.6 EAQ84120.1 - 0.035 13.8 0.0 0.49 10.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 EAQ84120.1 - 0.038 14.1 0.0 7.2 6.7 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA PF00004.29 EAQ84120.1 - 0.072 13.5 0.0 4 7.9 0.0 2.9 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.9 EAQ84120.1 - 0.076 12.8 0.0 8.1 6.2 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Zn_clus PF00172.18 EAQ84121.1 - 2.4e-08 34.0 11.6 2.4e-08 34.0 11.6 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EAQ84121.1 - 6.9e-08 31.8 0.1 1.3e-07 30.9 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain CDC37_C PF08564.10 EAQ84122.1 - 2.3e-28 98.2 0.9 2.3e-28 98.2 0.9 1.6 2 0 0 2 2 2 1 Cdc37 C terminal domain CDC37_M PF08565.11 EAQ84122.1 - 6.8e-21 74.4 0.1 1.1e-20 73.7 0.1 1.3 1 0 0 1 1 1 1 Cdc37 Hsp90 binding domain AAA_23 PF13476.6 EAQ84122.1 - 0.00073 20.1 0.0 0.0089 16.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 EAQ84122.1 - 0.00084 19.9 0.0 0.0017 18.9 0.0 1.8 1 1 0 1 1 1 1 ABC transporter AAA_30 PF13604.6 EAQ84122.1 - 0.0023 17.7 0.0 0.0069 16.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EAQ84122.1 - 0.0041 16.8 0.0 0.01 15.5 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain NACHT PF05729.12 EAQ84122.1 - 0.0049 16.8 0.1 0.017 15.1 0.0 1.9 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 EAQ84122.1 - 0.006 17.0 1.2 0.061 13.7 1.1 2.5 1 1 0 1 1 1 1 AAA ATPase domain TrwB_AAD_bind PF10412.9 EAQ84122.1 - 0.0062 15.5 0.0 0.98 8.3 0.1 2.2 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain AAA_22 PF13401.6 EAQ84122.1 - 0.0092 16.3 0.2 0.024 14.9 0.2 2.0 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 EAQ84122.1 - 0.022 15.1 0.0 0.056 13.8 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Ploopntkinase3 PF18751.1 EAQ84122.1 - 0.023 14.6 0.0 0.094 12.6 0.0 1.9 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_18 PF13238.6 EAQ84122.1 - 0.036 14.6 0.0 0.12 12.9 0.0 2.0 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EAQ84122.1 - 0.041 13.8 0.0 0.21 11.5 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase ATPase_2 PF01637.18 EAQ84122.1 - 0.12 12.3 0.0 0.33 10.8 0.0 1.7 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea DUF759 PF05537.11 EAQ84122.1 - 0.15 10.9 0.1 0.21 10.4 0.1 1.2 1 0 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF759) ATP_bind_1 PF03029.17 EAQ84122.1 - 0.19 11.5 0.1 0.63 9.8 0.0 1.9 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein ParD_antitoxin PF03693.14 EAQ84123.1 - 0.093 13.2 0.2 0.27 11.7 0.2 1.8 1 1 0 1 1 1 0 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH DUF2369 PF10179.9 EAQ84123.1 - 0.12 12.7 0.1 0.21 12.0 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2369) PI3K_C2 PF00792.24 EAQ84123.1 - 0.15 11.9 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 Phosphoinositide 3-kinase C2 CBM_1 PF00734.18 EAQ84124.1 - 7e-12 45.1 12.2 1e-11 44.5 10.9 2.1 2 0 0 2 2 2 1 Fungal cellulose binding domain Polysacc_lyase PF14099.6 EAQ84124.1 - 0.0082 16.0 0.1 0.03 14.2 0.1 1.9 1 1 0 1 1 1 1 Polysaccharide lyase ABC_membrane PF00664.23 EAQ84125.1 - 8.4e-29 101.1 11.6 1.4e-28 100.3 11.6 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EAQ84125.1 - 7.7e-21 75.1 0.3 7.7e-09 36.2 0.0 2.8 2 1 0 3 3 3 2 ABC transporter SMC_N PF02463.19 EAQ84125.1 - 2.1e-06 27.3 0.0 0.0016 17.9 0.0 2.5 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EAQ84125.1 - 5.8e-06 26.6 0.0 1.2e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EAQ84125.1 - 0.0025 17.5 0.1 0.0059 16.3 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 EAQ84125.1 - 0.013 15.9 0.1 0.034 14.5 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain MTABC_N PF16185.5 EAQ84125.1 - 0.028 13.9 0.1 0.1 12.1 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial ABC-transporter N-terminal five TM region AAA_30 PF13604.6 EAQ84125.1 - 0.056 13.2 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 EAQ84125.1 - 0.1 12.3 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain MMR_HSR1 PF01926.23 EAQ84125.1 - 0.11 12.6 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF87 PF01935.17 EAQ84125.1 - 0.14 12.3 0.2 0.33 11.0 0.1 1.5 2 0 0 2 2 2 0 Helicase HerA, central domain RsgA_GTPase PF03193.16 EAQ84125.1 - 0.16 11.9 0.0 0.35 10.8 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_10 PF12846.7 EAQ84125.1 - 0.17 10.8 0.1 0.38 9.6 0.0 1.5 2 0 0 2 2 2 0 AAA-like domain Frataxin_Cyay PF01491.16 EAQ84128.1 - 3.8e-37 126.6 0.0 4.8e-37 126.3 0.0 1.1 1 0 0 1 1 1 1 Frataxin-like domain Clat_adaptor_s PF01217.20 EAQ84129.1 - 9.9e-43 145.5 0.0 2.3e-42 144.3 0.0 1.5 1 1 0 1 1 1 1 Clathrin adaptor complex small chain TPR_10 PF13374.6 EAQ84130.1 - 3.2e-90 293.9 0.1 1.1e-11 44.2 0.1 8.6 8 0 0 8 8 8 8 Tetratricopeptide repeat TPR_12 PF13424.6 EAQ84130.1 - 5.5e-71 234.9 2.0 5e-16 58.8 0.0 7.1 2 1 5 7 7 7 7 Tetratricopeptide repeat TPR_7 PF13176.6 EAQ84130.1 - 8e-32 106.9 0.5 0.00027 20.7 0.0 8.4 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_16 PF13432.6 EAQ84130.1 - 2.9e-19 69.4 0.0 0.00063 20.3 0.0 8.5 5 2 3 8 8 7 5 Tetratricopeptide repeat TPR_2 PF07719.17 EAQ84130.1 - 9e-19 66.0 0.3 0.41 10.9 0.0 8.4 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_4 PF07721.14 EAQ84130.1 - 4.4e-16 57.8 0.0 14 6.7 0.0 9.2 8 1 1 9 9 9 0 Tetratricopeptide repeat TPR_1 PF00515.28 EAQ84130.1 - 1.5e-14 53.0 0.0 1.1 9.2 0.0 7.5 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_MalT PF17874.1 EAQ84130.1 - 1.6e-13 50.8 11.5 3.1e-10 39.9 3.3 2.6 1 1 1 2 2 2 2 MalT-like TPR region TPR_14 PF13428.6 EAQ84130.1 - 1.7e-12 47.1 4.9 7.8 7.6 0.0 8.9 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_19 PF14559.6 EAQ84130.1 - 2.2e-12 47.3 0.0 0.087 13.3 0.0 6.9 4 2 3 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 EAQ84130.1 - 5.6e-11 41.8 0.0 6.1 7.3 0.0 7.3 7 0 0 7 7 6 3 Tetratricopeptide repeat NB-ARC PF00931.22 EAQ84130.1 - 1.4e-07 31.0 0.0 3e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain PPR PF01535.20 EAQ84130.1 - 5e-07 29.5 1.9 27 5.3 0.0 6.5 6 0 0 6 6 6 0 PPR repeat TPR_3 PF07720.12 EAQ84130.1 - 5.4e-06 26.3 0.0 40 4.3 0.0 5.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_5 PF12688.7 EAQ84130.1 - 9.1e-06 25.9 0.0 13 6.0 0.0 5.2 1 1 4 5 5 5 0 Tetratrico peptide repeat TPR_17 PF13431.6 EAQ84130.1 - 9.9e-05 22.5 3.0 40 4.9 0.0 7.0 7 0 0 7 7 7 0 Tetratricopeptide repeat Ses_B PF17046.5 EAQ84130.1 - 0.00047 20.1 1.1 0.0011 18.9 1.1 1.7 1 0 0 1 1 1 1 SesB domain on fungal death-pathway protein NACHT PF05729.12 EAQ84130.1 - 0.0016 18.4 0.0 0.0031 17.5 0.0 1.5 1 0 0 1 1 1 1 NACHT domain TPR_6 PF13174.6 EAQ84130.1 - 0.0019 18.7 1.2 1.8e+02 3.1 0.0 6.3 7 0 0 7 7 6 0 Tetratricopeptide repeat AAA_25 PF13481.6 EAQ84130.1 - 0.0033 17.0 0.0 0.0062 16.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain Trans_reg_C PF00486.28 EAQ84130.1 - 0.0056 16.7 0.4 27 4.9 0.0 4.3 2 2 2 4 4 4 0 Transcriptional regulatory protein, C terminal PPR_1 PF12854.7 EAQ84130.1 - 0.019 14.6 3.1 90 2.9 0.0 5.4 6 0 0 6 6 6 0 PPR repeat Ntox35 PF15534.6 EAQ84130.1 - 0.019 15.4 1.3 75 3.9 0.0 4.4 5 0 0 5 5 5 0 Bacterial toxin 35 tRNA-synt_1 PF00133.22 EAQ84131.1 - 8.5e-39 133.3 0.0 3e-28 98.4 0.0 3.2 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 EAQ84131.1 - 2.7e-17 62.6 0.0 1.5e-10 40.4 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 EAQ84131.1 - 2.4e-13 50.3 0.3 5.1e-13 49.3 0.3 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 EAQ84131.1 - 3.5e-09 36.4 0.0 8.2e-09 35.2 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain ABG_transport PF03806.13 EAQ84132.1 - 0.025 12.8 5.9 0.027 12.7 5.9 1.1 1 0 0 1 1 1 0 AbgT putative transporter family zf-CSL PF05207.13 EAQ84133.1 - 9.9e-22 76.4 0.6 1.3e-21 76.1 0.6 1.1 1 0 0 1 1 1 1 CSL zinc finger zf-RING_4 PF14570.6 EAQ84133.1 - 0.035 13.9 0.4 0.054 13.3 0.4 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain TF_Zn_Ribbon PF08271.12 EAQ84133.1 - 0.038 13.5 0.5 0.038 13.5 0.5 1.6 2 0 0 2 2 2 0 TFIIB zinc-binding EF-hand_4 PF12763.7 EAQ84134.1 - 1.4e-27 95.7 0.0 5.1e-14 52.1 0.0 3.1 2 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.6 EAQ84134.1 - 7e-09 36.0 0.1 6.4e-06 26.5 0.2 3.5 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 EAQ84134.1 - 2.2e-05 23.7 0.0 2.7 7.8 0.0 3.9 4 0 0 4 4 3 2 EF hand DUF812 PF05667.11 EAQ84134.1 - 0.00024 20.2 16.7 0.00024 20.2 16.7 1.6 2 0 0 2 2 1 1 Protein of unknown function (DUF812) EF-hand_6 PF13405.6 EAQ84134.1 - 0.00079 19.2 0.1 1.7 8.8 0.0 3.9 4 0 0 4 4 3 1 EF-hand domain DUF3584 PF12128.8 EAQ84134.1 - 0.0022 15.6 25.6 0.0033 15.0 25.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) EF-hand_8 PF13833.6 EAQ84134.1 - 0.0046 16.8 0.0 10 6.1 0.0 3.3 3 0 0 3 3 3 0 EF-hand domain pair ADIP PF11559.8 EAQ84134.1 - 0.013 15.6 39.5 0.096 12.8 14.5 3.2 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding ATG16 PF08614.11 EAQ84134.1 - 0.016 15.4 41.6 0.033 14.4 21.6 3.6 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) PRKG1_interact PF15898.5 EAQ84134.1 - 0.018 15.9 12.3 0.018 15.9 12.3 3.6 1 1 2 3 3 3 0 cGMP-dependent protein kinase interacting domain Spc7 PF08317.11 EAQ84134.1 - 0.02 13.8 35.7 0.21 10.4 21.6 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein CENP-F_leu_zip PF10473.9 EAQ84134.1 - 0.026 14.5 33.7 0.082 12.9 14.4 3.3 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4618 PF15397.6 EAQ84134.1 - 0.073 12.5 22.1 0.6 9.5 19.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) TMF_TATA_bd PF12325.8 EAQ84134.1 - 0.08 13.2 29.0 0.73 10.1 5.4 3.4 1 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding GAS PF13851.6 EAQ84134.1 - 0.095 12.0 34.4 0.27 10.6 14.4 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF1192 PF06698.11 EAQ84134.1 - 1 9.5 4.2 3.9 7.6 0.8 3.3 3 0 0 3 3 2 0 Protein of unknown function (DUF1192) MAD PF05557.13 EAQ84134.1 - 1.1 7.5 27.8 1.8 6.8 27.8 1.2 1 0 0 1 1 1 0 Mitotic checkpoint protein kleA_kleC PF17383.2 EAQ84134.1 - 1.4 9.3 10.9 5.8 7.3 0.4 3.8 2 1 1 3 3 3 0 Uncharacterized KorC regulated protein A Macoilin PF09726.9 EAQ84134.1 - 1.5 7.3 27.6 0.0058 15.3 18.1 1.6 2 0 0 2 2 1 0 Macoilin family MPS2 PF17060.5 EAQ84134.1 - 1.6 7.9 17.2 3.1 7.0 17.2 1.4 1 0 0 1 1 1 0 Monopolar spindle protein 2 DUF3450 PF11932.8 EAQ84134.1 - 1.9 7.8 35.8 0.22 10.8 15.3 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF724 PF05266.14 EAQ84134.1 - 2.9 7.7 26.1 0.043 13.6 10.7 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF724) HAP1_N PF04849.13 EAQ84134.1 - 3.2 6.9 29.3 0.67 9.1 16.8 2.1 1 1 1 2 2 2 0 HAP1 N-terminal conserved region Csm1_N PF18504.1 EAQ84134.1 - 3.2 8.1 27.8 0.062 13.6 3.4 4.2 3 1 1 4 4 4 0 Csm1 N-terminal domain TPR_MLP1_2 PF07926.12 EAQ84134.1 - 3.3 7.8 47.2 0.065 13.3 25.2 2.6 2 1 1 3 3 2 0 TPR/MLP1/MLP2-like protein COG2 PF06148.11 EAQ84134.1 - 4 7.5 16.8 0.11 12.6 4.0 2.5 1 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Jnk-SapK_ap_N PF09744.9 EAQ84134.1 - 4.3 7.6 32.6 1.4 9.1 17.0 2.3 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 TolA_bind_tri PF16331.5 EAQ84134.1 - 4.3 7.5 38.2 0.47 10.6 2.3 4.6 2 1 3 5 5 4 0 TolA binding protein trimerisation Lebercilin PF15619.6 EAQ84134.1 - 4.4 6.9 32.8 9.1 5.9 32.8 1.5 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Fez1 PF06818.15 EAQ84134.1 - 6.3 7.2 29.9 50 4.3 30.1 2.1 1 1 0 1 1 1 0 Fez1 APG6_N PF17675.1 EAQ84134.1 - 6.6 7.3 38.5 13 6.4 19.8 3.1 1 1 2 3 3 3 0 Apg6 coiled-coil region Filament PF00038.21 EAQ84134.1 - 7.3 6.1 32.7 1.8 8.1 13.2 2.2 1 1 1 2 2 2 0 Intermediate filament protein FUSC PF04632.12 EAQ84134.1 - 7.8 4.9 8.9 13 4.2 8.9 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family MbeD_MobD PF04899.12 EAQ84134.1 - 8 6.7 25.9 2 8.6 0.4 4.8 4 1 1 5 5 5 0 MbeD/MobD like HrpB7 PF09486.10 EAQ84134.1 - 8.4 6.8 20.5 8.3 6.8 18.4 2.1 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) HOOK PF05622.12 EAQ84134.1 - 8.7 4.4 34.4 0.8 7.8 10.8 2.0 1 1 1 2 2 2 0 HOOK protein Golgin_A5 PF09787.9 EAQ84134.1 - 9.6 5.6 32.1 1.2 8.6 26.0 1.9 1 1 1 2 2 2 0 Golgin subfamily A member 5 Tubulin PF00091.25 EAQ84135.1 - 8.2e-65 218.7 0.0 1.2e-64 218.2 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EAQ84135.1 - 1.5e-50 170.5 0.1 2.6e-50 169.8 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 EAQ84135.1 - 0.0012 18.6 0.0 0.0031 17.2 0.0 1.7 2 0 0 2 2 2 1 Tubulin domain BTB_2 PF02214.22 EAQ84136.1 - 1e-05 25.8 0.1 0.0047 17.3 0.0 2.3 2 0 0 2 2 2 2 BTB/POZ domain EcsC PF12787.7 EAQ84137.1 - 0.074 12.7 3.4 0.066 12.9 0.7 2.1 3 0 0 3 3 3 0 EcsC protein family Cnn_1N PF07989.11 EAQ84137.1 - 1 9.5 5.5 0.17 12.0 0.4 2.1 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 Cyt-b5 PF00173.28 EAQ84139.1 - 4.2e-10 39.6 0.0 6.8e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain CENP-X PF09415.10 EAQ84141.1 - 2.9e-24 85.2 0.2 2.9e-24 85.2 0.2 2.0 2 0 0 2 2 2 1 CENP-S associating Centromere protein X DUF4604 PF15377.6 EAQ84141.1 - 0.01 16.3 7.6 0.017 15.6 7.4 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4604) Pinin_SDK_N PF04697.13 EAQ84141.1 - 0.024 15.3 7.6 0.024 15.3 7.6 1.8 2 0 0 2 2 2 0 pinin/SDK conserved region Mito_carr PF00153.27 EAQ84142.1 - 2.5e-66 219.7 7.0 1.3e-23 82.8 0.3 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_S25 PF03297.15 EAQ84143.1 - 1.6e-38 130.9 5.2 1.8e-38 130.8 5.2 1.0 1 0 0 1 1 1 1 S25 ribosomal protein RNA_pol_Rpc34 PF05158.12 EAQ84143.1 - 0.0018 17.7 0.3 0.0031 17.0 0.1 1.4 1 1 0 1 1 1 1 RNA polymerase Rpc34 subunit HTH_24 PF13412.6 EAQ84143.1 - 0.0021 17.6 0.2 0.0035 16.9 0.2 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_DeoR PF08220.12 EAQ84143.1 - 0.0066 16.2 0.1 0.0092 15.7 0.1 1.2 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain Rrf2 PF02082.20 EAQ84143.1 - 0.014 15.7 0.0 0.021 15.1 0.0 1.2 1 0 0 1 1 1 0 Transcriptional regulator MarR_2 PF12802.7 EAQ84143.1 - 0.038 13.9 0.0 0.048 13.6 0.0 1.2 1 0 0 1 1 1 0 MarR family HTH_11 PF08279.12 EAQ84143.1 - 0.058 13.3 0.1 0.078 12.9 0.1 1.2 1 0 0 1 1 1 0 HTH domain HTH_IclR PF09339.10 EAQ84143.1 - 0.078 12.8 0.0 0.093 12.5 0.0 1.2 1 0 0 1 1 1 0 IclR helix-turn-helix domain Ribosomal_S7 PF00177.21 EAQ84144.1 - 2.3e-37 128.0 1.9 2.9e-37 127.6 1.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Acetyltransf_1 PF00583.25 EAQ84145.1 - 7.6e-07 29.4 0.0 9.5e-06 25.8 0.0 2.6 2 1 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EAQ84145.1 - 3.4e-06 27.0 0.0 0.047 13.6 0.0 2.4 1 1 1 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EAQ84145.1 - 1e-05 25.9 0.0 4.8e-05 23.7 0.0 2.1 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EAQ84145.1 - 9.9e-05 22.4 0.0 0.0002 21.4 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_5 PF13444.6 EAQ84145.1 - 0.001 19.8 0.0 1.3 9.7 0.0 3.0 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain SUKH-4 PF14435.6 EAQ84145.1 - 0.0057 16.7 0.3 0.03 14.4 0.1 2.0 2 0 0 2 2 2 1 SUKH-4 immunity protein FR47 PF08445.10 EAQ84145.1 - 0.011 15.6 0.0 0.11 12.5 0.0 2.2 2 0 0 2 2 2 0 FR47-like protein ECR1_N PF14382.6 EAQ84145.1 - 0.016 15.0 0.0 0.058 13.2 0.0 2.0 1 0 0 1 1 1 0 Exosome complex exonuclease RRP4 N-terminal region DUF3335 PF11814.8 EAQ84145.1 - 0.054 13.0 0.0 0.077 12.5 0.0 1.2 1 0 0 1 1 1 0 Peptidase_C39 like family Acetyltransf_9 PF13527.7 EAQ84145.1 - 0.1 12.7 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain adh_short PF00106.25 EAQ84146.1 - 4.4e-42 143.8 0.0 5.6e-42 143.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EAQ84146.1 - 3.6e-41 141.3 0.0 4.8e-41 140.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EAQ84146.1 - 2.1e-08 34.3 0.0 3.2e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EAQ84146.1 - 0.00072 19.1 0.0 0.0011 18.5 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EAQ84146.1 - 0.0035 16.5 0.0 0.0094 15.1 0.0 1.7 1 1 1 2 2 2 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 EAQ84146.1 - 0.024 14.1 0.0 0.044 13.2 0.0 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase PIGA PF08288.12 EAQ84148.1 - 8.4e-47 157.7 4.0 1.6e-46 156.8 1.5 2.5 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glyco_transf_4 PF13439.6 EAQ84148.1 - 1.5e-30 106.5 0.8 2.6e-30 105.7 0.8 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 EAQ84148.1 - 5.4e-26 91.2 0.0 8.3e-26 90.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EAQ84148.1 - 4e-23 82.3 0.1 8.1e-23 81.3 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 EAQ84148.1 - 2e-15 57.6 0.0 3.8e-15 56.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 EAQ84148.1 - 2.9e-07 30.6 0.1 6.6e-07 29.4 0.1 1.5 2 0 0 2 2 2 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.6 EAQ84148.1 - 0.00061 20.1 0.0 0.0024 18.2 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 EAQ84148.1 - 0.072 12.8 0.0 0.17 11.5 0.0 1.8 1 1 0 1 1 1 0 Starch synthase catalytic domain DEAD PF00270.29 EAQ84149.1 - 5.2e-32 111.0 0.0 2.8e-15 56.5 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 EAQ84149.1 - 3.2e-20 72.5 0.0 1.4e-19 70.4 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EAQ84149.1 - 3.4e-06 27.2 0.0 3.4e-06 27.2 0.0 2.7 2 2 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 EAQ84149.1 - 0.081 13.3 0.1 0.75 10.1 0.0 2.3 2 1 0 2 2 2 0 AAA domain Flavi_DEAD PF07652.14 EAQ84149.1 - 0.087 12.8 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain PAC4 PF16093.5 EAQ84149.1 - 0.19 11.9 0.5 0.86 9.8 0.3 2.1 2 0 0 2 2 2 0 Proteasome assembly chaperone 4 MID_MedPIWI PF18296.1 EAQ84149.1 - 9 6.0 9.7 1.4 8.6 1.2 2.4 2 0 0 2 2 2 0 MID domain of medPIWI HSP70 PF00012.20 EAQ84150.1 - 1.3e-34 119.4 9.1 3.1e-18 65.3 10.2 4.3 3 1 0 3 3 3 2 Hsp70 protein Trimer_CC PF08954.11 EAQ84150.1 - 0.0087 15.6 0.1 1.1 8.9 0.2 3.5 3 0 0 3 3 3 1 Trimerisation motif HET PF06985.11 EAQ84151.1 - 1.1e-27 97.1 0.0 2e-27 96.3 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF16 PF01519.16 EAQ84152.1 - 0.0046 17.4 0.3 0.0067 16.9 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF16 Filament PF00038.21 EAQ84152.1 - 0.0092 15.6 1.0 0.012 15.2 1.0 1.1 1 0 0 1 1 1 1 Intermediate filament protein SlyX PF04102.12 EAQ84152.1 - 0.011 16.4 0.1 0.022 15.3 0.1 1.6 1 0 0 1 1 1 0 SlyX XhlA PF10779.9 EAQ84152.1 - 0.026 14.7 0.6 0.04 14.1 0.6 1.2 1 0 0 1 1 1 0 Haemolysin XhlA LXG PF04740.12 EAQ84152.1 - 0.029 14.1 0.2 0.045 13.4 0.2 1.2 1 0 0 1 1 1 0 LXG domain of WXG superfamily Spc7 PF08317.11 EAQ84152.1 - 0.037 12.9 0.7 0.046 12.6 0.7 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF1729 PF08354.10 EAQ84152.1 - 0.049 12.5 0.1 0.064 12.2 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1729) AAA_13 PF13166.6 EAQ84152.1 - 0.07 11.8 0.2 0.09 11.4 0.2 1.0 1 0 0 1 1 1 0 AAA domain Tup_N PF08581.10 EAQ84152.1 - 0.17 12.2 1.8 1.5 9.2 0.6 2.0 1 1 1 2 2 2 0 Tup N-terminal DivIC PF04977.15 EAQ84152.1 - 0.18 11.6 2.7 0.39 10.5 2.7 1.5 1 1 0 1 1 1 0 Septum formation initiator Fib_alpha PF08702.10 EAQ84152.1 - 0.24 11.6 1.2 0.35 11.1 1.2 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Arginase PF00491.21 EAQ84153.1 - 0.042 13.3 0.0 0.053 13.0 0.0 1.1 1 0 0 1 1 1 0 Arginase family HET PF06985.11 EAQ84154.1 - 9.9e-31 107.1 0.0 3.4e-30 105.3 0.0 1.9 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Glyco_hydro_11 PF00457.17 EAQ84155.1 - 1.3e-74 249.7 17.6 1.5e-74 249.5 17.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 PIF1 PF05970.14 EAQ84157.1 - 5.5e-09 35.7 0.1 9.7e-09 34.9 0.1 1.3 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 EAQ84157.1 - 2.1e-05 24.3 0.3 6.1e-05 22.8 0.1 1.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EAQ84157.1 - 0.00017 21.9 0.0 0.00047 20.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 EAQ84157.1 - 0.0096 15.7 0.0 0.028 14.2 0.0 1.9 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain DUF1996 PF09362.10 EAQ84158.1 - 1.5e-78 264.1 0.7 1.9e-78 263.7 0.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Ceramidase PF05875.12 EAQ84159.1 - 9e-46 156.4 1.3 1e-45 156.3 1.3 1.0 1 0 0 1 1 1 1 Ceramidase TetR_C_29 PF17938.1 EAQ84159.1 - 0.23 11.6 1.4 0.24 11.5 0.1 1.7 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain UNC-93 PF05978.16 EAQ84159.1 - 7.2 6.3 10.6 17 5.1 0.3 2.4 2 1 0 2 2 2 0 Ion channel regulatory protein UNC-93 Bromodomain PF00439.25 EAQ84160.1 - 3.9e-07 30.0 0.0 2.8e-06 27.3 0.0 2.2 1 1 0 1 1 1 1 Bromodomain PE PF00934.20 EAQ84160.1 - 0.16 12.3 2.1 0.47 10.8 2.1 1.7 1 0 0 1 1 1 0 PE family DUF465 PF04325.13 EAQ84160.1 - 0.18 11.9 0.1 0.52 10.4 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF465) mRNA_decap_C PF16741.5 EAQ84160.1 - 4.5 6.7 5.5 4.1 6.8 0.3 2.8 3 0 0 3 3 3 0 mRNA-decapping enzyme C-terminus APH PF01636.23 EAQ84161.1 - 2.2e-07 31.1 0.2 3e-06 27.3 0.2 2.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 EAQ84161.1 - 0.0001 21.8 0.0 0.00017 21.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 EAQ84161.1 - 0.0011 18.6 0.0 0.0018 17.9 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 EAQ84161.1 - 0.0012 18.4 0.1 0.0019 17.8 0.1 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase HSP70 PF00012.20 EAQ84164.1 - 1.4e-07 30.1 0.0 8e-05 21.0 0.0 2.9 2 1 0 2 2 2 2 Hsp70 protein RuvX PF03652.15 EAQ84164.1 - 0.069 13.5 0.0 9.8 6.6 0.0 3.1 3 0 0 3 3 3 0 Holliday junction resolvase BcrAD_BadFG PF01869.20 EAQ84164.1 - 0.37 10.2 1.1 0.46 9.9 0.0 1.7 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Tropomyosin PF00261.20 EAQ84165.1 - 0.00065 19.1 4.0 0.0012 18.2 4.0 1.4 1 0 0 1 1 1 1 Tropomyosin CCDC144C PF14915.6 EAQ84165.1 - 0.0076 15.4 4.9 0.012 14.7 4.9 1.2 1 0 0 1 1 1 1 CCDC144C protein coiled-coil region CENP-F_leu_zip PF10473.9 EAQ84165.1 - 0.0084 16.1 4.5 0.021 14.9 4.5 1.6 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HAP1_N PF04849.13 EAQ84165.1 - 0.01 15.1 6.3 0.024 13.9 6.4 1.5 1 1 0 1 1 1 0 HAP1 N-terminal conserved region HOOK PF05622.12 EAQ84165.1 - 0.012 13.8 3.5 0.018 13.2 3.5 1.1 1 0 0 1 1 1 0 HOOK protein TPR_MLP1_2 PF07926.12 EAQ84165.1 - 0.021 14.9 9.2 0.069 13.2 6.6 2.3 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Uso1_p115_C PF04871.13 EAQ84165.1 - 0.029 14.7 4.3 0.068 13.5 4.3 1.6 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Fib_alpha PF08702.10 EAQ84165.1 - 0.045 13.9 2.4 0.094 12.9 2.4 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Fez1 PF06818.15 EAQ84165.1 - 0.069 13.6 3.2 0.12 12.8 3.2 1.3 1 0 0 1 1 1 0 Fez1 Jnk-SapK_ap_N PF09744.9 EAQ84165.1 - 0.081 13.1 7.6 0.98 9.6 8.2 2.2 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Golgin_A5 PF09787.9 EAQ84165.1 - 0.16 11.4 4.8 0.25 10.8 4.8 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 MIF4G_like_2 PF09090.11 EAQ84165.1 - 0.24 10.9 1.5 0.37 10.2 1.5 1.2 1 0 0 1 1 1 0 MIF4G like DUF1640 PF07798.11 EAQ84165.1 - 0.24 11.4 3.7 0.48 10.5 3.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) V_ATPase_I PF01496.19 EAQ84165.1 - 0.25 9.2 0.3 0.3 8.9 0.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SlyX PF04102.12 EAQ84165.1 - 0.34 11.6 5.0 2.8 8.6 4.4 3.1 2 0 0 2 2 1 0 SlyX DUF4407 PF14362.6 EAQ84165.1 - 0.56 9.5 5.2 0.87 8.9 5.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) YabA PF06156.13 EAQ84165.1 - 1.4 9.6 4.1 24 5.6 1.6 2.5 1 1 1 2 2 2 0 Initiation control protein YabA GAS PF13851.6 EAQ84165.1 - 1.5 8.1 6.3 0.59 9.4 3.7 1.6 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding ZapB PF06005.12 EAQ84165.1 - 3.3 8.2 10.5 4 7.9 0.0 2.5 2 0 0 2 2 2 0 Cell division protein ZapB IBR PF01485.21 EAQ84166.1 - 2.1e-23 82.3 27.2 4.9e-13 49.1 2.5 3.5 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 EAQ84166.1 - 0.0074 16.1 25.0 0.31 11.0 7.5 3.0 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) DUF2052 PF09747.9 EAQ84166.1 - 0.15 12.2 14.2 1.1 9.4 11.2 2.3 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) TFIIA PF03153.13 EAQ84166.1 - 0.36 10.8 11.7 0.74 9.8 0.8 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit zf-4CXXC_R1 PF10497.9 EAQ84166.1 - 4.1 7.7 16.4 9.2 6.6 7.6 2.8 2 0 0 2 2 2 0 Zinc-finger domain of monoamine-oxidase A repressor R1 OrfB_Zn_ribbon PF07282.11 EAQ84166.1 - 6.2 6.8 9.7 9.9 6.2 4.6 2.7 2 0 0 2 2 2 0 Putative transposase DNA-binding domain His_Phos_1 PF00300.22 EAQ84167.1 - 1.4e-22 80.3 4.5 1.6e-20 73.6 4.5 2.9 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) RasGEF PF00617.19 EAQ84168.1 - 8.4e-49 166.2 0.0 1.7e-48 165.2 0.0 1.5 1 0 0 1 1 1 1 RasGEF domain DNA_binding_1 PF01035.20 EAQ84168.1 - 1.5e-24 85.9 0.1 2.9e-24 85.0 0.1 1.5 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain RasGEF_N PF00618.20 EAQ84168.1 - 1.3e-13 51.1 0.0 3.5e-13 49.7 0.0 1.8 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_9 PF14604.6 EAQ84168.1 - 9.8e-07 28.5 0.0 2.2e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EAQ84168.1 - 2.4e-05 23.8 0.0 0.00012 21.6 0.0 2.0 2 0 0 2 2 2 1 SH3 domain I_LWEQ PF01608.17 EAQ84168.1 - 0.069 13.4 0.1 5.2 7.3 0.0 3.1 3 0 0 3 3 3 0 I/LWEQ domain Jacalin PF01419.17 EAQ84169.1 - 0.038 13.9 0.0 0.084 12.8 0.0 1.5 1 0 0 1 1 1 0 Jacalin-like lectin domain MFS_1 PF07690.16 EAQ84170.1 - 7.1e-17 61.4 30.9 7.1e-17 61.4 30.9 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 EAQ84170.1 - 1.3e-11 44.4 3.4 1.3e-11 44.4 3.4 2.6 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 MFS_1_like PF12832.7 EAQ84170.1 - 0.00034 19.6 2.1 0.001 18.0 2.1 1.8 1 0 0 1 1 1 1 MFS_1 like family AcetylCoA_hyd_C PF13336.6 EAQ84171.1 - 1.5e-39 135.4 0.0 2.2e-39 134.9 0.0 1.2 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain AcetylCoA_hydro PF02550.15 EAQ84171.1 - 5.9e-33 114.5 0.0 1.9e-31 109.6 0.0 2.2 1 1 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain GH131_N PF18271.1 EAQ84172.1 - 1.4e-66 224.8 0.8 1.7e-66 224.5 0.8 1.1 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain CBM_1 PF00734.18 EAQ84172.1 - 4.7e-09 36.0 13.6 4.7e-09 36.0 13.6 2.2 2 0 0 2 2 2 1 Fungal cellulose binding domain MFS_1 PF07690.16 EAQ84173.1 - 2.7e-22 79.2 53.8 1.2e-19 70.5 34.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EAQ84173.1 - 4.9e-16 58.6 26.1 3.8e-15 55.7 26.1 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter RPAP1_C PF08620.10 EAQ84173.1 - 0.0027 17.8 0.0 0.0059 16.7 0.0 1.5 1 0 0 1 1 1 1 RPAP1-like, C-terminal Flavi_NS4A PF01350.17 EAQ84173.1 - 0.064 13.2 2.0 0.079 12.9 0.1 2.1 2 0 0 2 2 2 0 Flavivirus non-structural protein NS4A DUF2583 PF10762.9 EAQ84173.1 - 0.84 10.1 4.6 0.33 11.4 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2583) DUF4405 PF14358.6 EAQ84173.1 - 3.3 8.3 11.4 0.31 11.6 3.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4405) MtN3_slv PF03083.16 EAQ84173.1 - 4.1 7.5 8.5 0.19 11.8 1.1 2.7 3 0 0 3 3 3 0 Sugar efflux transporter for intercellular exchange Sulfotransfer_4 PF17784.1 EAQ84174.1 - 7.7e-64 215.5 0.1 1e-63 215.0 0.1 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 EAQ84174.1 - 0.029 14.7 0.1 2 8.8 0.0 2.4 1 1 1 2 2 2 0 Sulfotransferase family Epimerase PF01370.21 EAQ84175.1 - 2e-12 47.1 0.0 2.6e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 EAQ84175.1 - 4.7e-05 22.7 0.2 0.00085 18.6 0.0 2.2 2 0 0 2 2 2 1 Male sterility protein GDP_Man_Dehyd PF16363.5 EAQ84175.1 - 0.0016 17.9 0.0 0.0036 16.8 0.0 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EAQ84175.1 - 0.24 10.5 0.0 4.3 6.4 0.0 2.1 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein RVT_1 PF00078.27 EAQ84176.1 - 3e-25 89.0 0.0 1.5e-24 86.7 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 EAQ84176.1 - 3.4e-24 85.0 0.0 1.2e-23 83.2 0.0 2.0 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 EAQ84176.1 - 9.7e-05 22.0 0.2 0.00022 20.8 0.2 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-CCHC PF00098.23 EAQ84176.1 - 0.0024 17.9 1.7 0.0024 17.9 1.7 2.5 2 0 0 2 2 1 1 Zinc knuckle SlyX PF04102.12 EAQ84176.1 - 0.0049 17.5 5.6 0.07 13.8 5.6 2.9 1 1 0 1 1 1 1 SlyX USP8_interact PF08941.10 EAQ84176.1 - 0.067 13.0 0.1 0.18 11.6 0.1 1.8 1 0 0 1 1 1 0 USP8 interacting CENP-F_leu_zip PF10473.9 EAQ84176.1 - 0.076 13.0 0.8 0.22 11.6 0.8 1.8 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CorA PF01544.18 EAQ84176.1 - 0.078 12.3 1.5 0.15 11.4 1.5 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein HMMR_N PF15905.5 EAQ84176.1 - 0.079 12.4 0.4 0.14 11.6 0.4 1.2 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal PKcGMP_CC PF16808.5 EAQ84176.1 - 0.11 12.3 0.6 0.37 10.7 0.6 1.9 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF3584 PF12128.8 EAQ84176.1 - 0.28 8.6 4.6 0.44 8.0 4.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) UPF0242 PF06785.11 EAQ84176.1 - 0.31 11.1 1.3 0.62 10.1 1.3 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Exonuc_VII_L PF02601.15 EAQ84176.1 - 0.66 9.5 4.5 1.5 8.3 4.5 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit YlqD PF11068.8 EAQ84176.1 - 0.71 10.3 3.6 2.5 8.5 3.6 1.9 1 0 0 1 1 1 0 YlqD protein zf-RVT PF13966.6 EAQ84176.1 - 0.71 10.6 0.0 0.71 10.6 0.0 2.5 2 0 0 2 2 1 0 zinc-binding in reverse transcriptase TPR_12 PF13424.6 EAQ84177.1 - 1.4e-19 70.2 2.2 5.4e-08 33.0 0.0 4.3 2 1 1 4 4 4 4 Tetratricopeptide repeat Patatin PF01734.22 EAQ84177.1 - 1.9e-15 57.6 0.0 4.1e-15 56.5 0.0 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase TPR_10 PF13374.6 EAQ84177.1 - 3e-15 55.5 8.1 1.5e-05 24.7 0.0 5.6 6 0 0 6 6 6 4 Tetratricopeptide repeat NB-ARC PF00931.22 EAQ84177.1 - 2.6e-05 23.5 0.0 5.2e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain TPR_MalT PF17874.1 EAQ84177.1 - 0.00058 19.3 3.0 0.0066 15.9 1.8 2.3 2 0 0 2 2 2 1 MalT-like TPR region TPR_16 PF13432.6 EAQ84177.1 - 0.0011 19.5 5.0 0.68 10.6 0.1 4.3 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 EAQ84177.1 - 0.011 15.7 7.4 0.71 10.1 0.6 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 EAQ84177.1 - 0.084 12.9 0.6 46 4.4 0.0 4.7 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.6 EAQ84177.1 - 1.1 9.7 3.1 20 5.7 0.3 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat SET PF00856.28 EAQ84180.1 - 0.038 14.4 0.0 0.061 13.7 0.0 1.2 1 0 0 1 1 1 0 SET domain P4Ha_N PF08336.11 EAQ84181.1 - 0.073 13.1 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region RVT_1 PF00078.27 EAQ84182.1 - 2.8e-46 157.8 0.0 4.3e-46 157.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 EAQ84182.1 - 9.3e-12 44.8 0.0 2.7e-11 43.3 0.0 1.8 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 EAQ84182.1 - 4.4e-05 23.1 0.2 0.00012 21.7 0.2 1.7 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RecC_C PF17946.1 EAQ84182.1 - 0.056 13.2 4.9 0.97 9.2 0.6 2.5 2 0 0 2 2 2 0 RecC C-terminal domain zf-NADH-PPase PF09297.11 EAQ84182.1 - 0.86 9.3 7.3 11 5.8 0.5 3.0 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Mu-like_Com PF10122.9 EAQ84182.1 - 1.3 8.6 4.3 12 5.5 0.9 3.2 3 0 0 3 3 3 0 Mu-like prophage protein Com Ank_2 PF12796.7 EAQ84183.1 - 2.5e-82 271.5 7.5 2.5e-13 50.4 0.0 7.2 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAQ84183.1 - 4.9e-66 218.3 10.9 6.9e-11 42.5 0.0 9.4 4 3 5 9 9 9 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAQ84183.1 - 2.7e-62 206.0 24.4 1.8e-09 37.6 0.0 11.4 4 3 7 11 11 11 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAQ84183.1 - 2.9e-61 196.2 13.5 0.00038 20.7 0.0 13.8 13 0 0 13 13 13 13 Ankyrin repeat Ank PF00023.30 EAQ84183.1 - 2.4e-51 170.0 29.4 6e-05 23.3 0.0 13.0 12 1 0 12 12 12 12 Ankyrin repeat HET PF06985.11 EAQ84185.1 - 4.8e-29 101.6 0.0 1.2e-28 100.2 0.0 1.8 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) AAA PF00004.29 EAQ84186.1 - 0.0017 18.8 0.0 0.0043 17.5 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Torsin PF06309.11 EAQ84186.1 - 0.02 15.0 0.0 0.064 13.4 0.0 1.8 2 0 0 2 2 2 0 Torsin FAM221 PF14753.6 EAQ84187.1 - 0.022 14.3 3.2 0.023 14.2 3.2 1.1 1 0 0 1 1 1 0 Protein FAM221A/B AFOR_N PF02730.15 EAQ84187.1 - 0.059 13.2 0.0 0.059 13.2 0.0 1.0 1 0 0 1 1 1 0 Aldehyde ferredoxin oxidoreductase, N-terminal domain Pkinase PF00069.25 EAQ84188.1 - 1.6e-07 31.0 0.0 4.3e-07 29.6 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain TauD PF02668.16 EAQ84189.1 - 4.8e-27 95.4 0.0 1e-26 94.4 0.0 1.5 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 EAQ84189.1 - 0.015 14.4 0.0 0.026 13.7 0.0 1.3 1 0 0 1 1 1 0 CsiD Zn_clus PF00172.18 EAQ84189.1 - 0.34 11.1 6.4 0.69 10.1 6.4 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.25 EAQ84190.1 - 0.041 13.2 0.0 0.066 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain PI3_PI4_kinase PF00454.27 EAQ84190.1 - 0.15 11.8 0.1 0.32 10.8 0.1 1.5 1 1 0 1 1 1 0 Phosphatidylinositol 3- and 4-kinase CbtB PF09489.10 EAQ84190.1 - 2.2 8.5 7.5 5.2 7.3 0.1 2.8 3 0 0 3 3 3 0 Probable cobalt transporter subunit (CbtB) DUF1992 PF09350.10 EAQ84191.1 - 3.2e-21 75.3 0.7 7.6e-21 74.1 0.7 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1992) Acetyltransf_10 PF13673.7 EAQ84191.1 - 0.00031 20.7 0.0 0.00074 19.5 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EAQ84191.1 - 0.012 16.0 0.0 0.024 15.1 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain MgsA_C PF12002.8 EAQ84195.1 - 3.4e-60 202.8 0.0 6.5e-60 201.9 0.0 1.4 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA_assoc_2 PF16193.5 EAQ84195.1 - 4.3e-24 84.7 0.0 9.7e-24 83.5 0.0 1.6 1 0 0 1 1 1 1 AAA C-terminal domain AAA PF00004.29 EAQ84195.1 - 2e-12 47.7 0.0 3.9e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EAQ84195.1 - 4.2e-08 33.1 0.0 9.9e-08 31.9 0.0 1.6 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EAQ84195.1 - 2.6e-05 24.7 2.6 0.0081 16.6 0.1 3.3 1 1 1 3 3 3 1 AAA ATPase domain Sigma54_activat PF00158.26 EAQ84195.1 - 4.2e-05 23.3 0.1 0.0025 17.5 0.1 2.5 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_22 PF13401.6 EAQ84195.1 - 0.00037 20.8 0.6 0.0023 18.2 0.6 2.4 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 EAQ84195.1 - 0.00058 19.3 0.0 0.26 10.6 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EAQ84195.1 - 0.0011 19.0 0.2 0.035 14.1 0.1 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 EAQ84195.1 - 0.0034 16.7 0.0 0.0054 16.0 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain DUF815 PF05673.13 EAQ84195.1 - 0.0041 16.3 0.0 0.0073 15.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) SKI PF01202.22 EAQ84195.1 - 0.0045 17.1 0.0 0.0091 16.1 0.0 1.5 1 0 0 1 1 1 1 Shikimate kinase DNA_pol3_delta2 PF13177.6 EAQ84195.1 - 0.024 14.4 0.0 2.4 7.9 0.0 2.3 1 1 1 2 2 2 0 DNA polymerase III, delta subunit AAA_3 PF07726.11 EAQ84195.1 - 0.03 14.2 0.0 0.16 11.8 0.0 2.2 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 EAQ84195.1 - 0.032 14.3 0.0 0.055 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EAQ84195.1 - 0.049 13.9 0.2 0.11 12.7 0.2 1.7 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 EAQ84195.1 - 0.049 13.6 0.1 2.6 8.0 0.0 2.3 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit AAA_19 PF13245.6 EAQ84195.1 - 0.049 14.0 0.2 0.31 11.4 0.2 2.0 1 1 0 2 2 2 0 AAA domain zf-WRNIP1_ubi PF18279.1 EAQ84195.1 - 0.061 14.0 0.5 0.17 12.6 0.1 2.1 2 0 0 2 2 1 0 Werner helicase-interacting protein 1 ubiquitin-binding domain TniB PF05621.11 EAQ84195.1 - 0.065 12.6 0.0 0.25 10.8 0.0 1.9 1 1 1 2 2 2 0 Bacterial TniB protein Cytidylate_kin PF02224.18 EAQ84195.1 - 0.075 12.7 0.1 0.42 10.3 0.0 2.0 2 0 0 2 2 2 0 Cytidylate kinase AAA_18 PF13238.6 EAQ84195.1 - 0.089 13.3 0.0 0.18 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EAQ84195.1 - 0.095 13.2 0.3 0.57 10.7 0.0 2.2 2 0 0 2 2 2 0 ABC transporter AAA_24 PF13479.6 EAQ84195.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF2059 PF09832.9 EAQ84195.1 - 0.14 12.3 0.5 1.5 9.0 0.2 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2059) RNF220 PF15926.5 EAQ84195.1 - 0.16 11.6 0.4 0.24 11.0 0.4 1.3 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase RNF220 Fe-S_biosyn PF01521.20 EAQ84196.1 - 7.3e-14 51.9 0.0 1.1e-13 51.4 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis DUF1631 PF07793.11 EAQ84196.1 - 0.16 10.3 2.9 0.19 10.1 2.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) Spt20 PF12090.8 EAQ84196.1 - 0.18 11.4 6.1 0.24 11.0 6.1 1.1 1 0 0 1 1 1 0 Spt20 family Ndc1_Nup PF09531.10 EAQ84196.1 - 1 8.0 4.0 1.1 7.9 4.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Mitofilin PF09731.9 EAQ84196.1 - 1.4 7.7 6.0 1.7 7.4 6.0 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF1741 PF08427.10 EAQ84197.1 - 2.5e-88 295.7 0.0 4.3e-88 294.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1741) CLN3 PF02487.17 EAQ84201.1 - 9.4e-161 535.3 0.6 1.1e-160 535.1 0.6 1.0 1 0 0 1 1 1 1 CLN3 protein Peptidase_M28 PF04389.17 EAQ84202.1 - 6.6e-37 127.1 0.1 1.5e-36 126.0 0.1 1.5 1 1 0 1 1 1 1 Peptidase family M28 PA PF02225.22 EAQ84202.1 - 3.2e-15 55.9 1.0 7e-15 54.8 1.0 1.6 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 EAQ84202.1 - 5.3e-06 26.3 0.0 1.1e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M13 PF01431.21 EAQ84203.1 - 4.8e-57 192.9 0.1 9e-57 192.0 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13_N PF05649.13 EAQ84203.1 - 5.1e-52 177.8 0.0 8.2e-52 177.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M13 Dimer_Tnp_hAT PF05699.14 EAQ84204.1 - 5.8e-13 48.5 0.1 1.3e-12 47.3 0.1 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Pkinase PF00069.25 EAQ84204.1 - 6.1e-11 42.2 0.0 8.8e-09 35.1 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ84204.1 - 0.00037 19.9 0.0 0.00065 19.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Amidase PF01425.21 EAQ84205.1 - 6.5e-45 153.9 1.5 2.8e-44 151.8 1.6 2.0 1 1 0 1 1 1 1 Amidase DUF3176 PF11374.8 EAQ84205.1 - 0.11 12.8 0.1 0.27 11.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3176) URO-D PF01208.17 EAQ84206.1 - 0.14 11.3 0.0 0.24 10.5 0.0 1.4 1 1 0 1 1 1 0 Uroporphyrinogen decarboxylase (URO-D) TPR_12 PF13424.6 EAQ84207.1 - 1e-10 41.8 3.2 8.1e-09 35.7 1.9 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 EAQ84207.1 - 1.2e-09 37.6 8.8 0.0025 17.8 0.1 4.8 4 0 0 4 4 4 3 Tetratricopeptide repeat NB-ARC PF00931.22 EAQ84207.1 - 4.1e-09 36.0 0.0 8.7e-09 34.9 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 EAQ84207.1 - 1.2e-06 29.0 0.0 1.4e-05 25.5 0.0 2.6 3 0 0 3 3 3 1 AAA ATPase domain TPR_1 PF00515.28 EAQ84207.1 - 4.6e-06 26.2 8.3 0.036 13.9 0.1 4.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 EAQ84207.1 - 4.3e-05 23.4 3.9 0.34 11.2 0.2 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 EAQ84207.1 - 5e-05 23.8 4.0 2.4 9.2 0.1 4.4 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 EAQ84207.1 - 0.00014 21.4 1.0 0.00014 21.4 1.0 3.0 3 0 0 3 3 2 1 TPR repeat TPR_10 PF13374.6 EAQ84207.1 - 0.00019 21.2 3.7 0.0078 16.1 0.7 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat HTH_OrfB_IS605 PF12323.8 EAQ84207.1 - 0.0005 19.5 0.9 0.0023 17.4 0.3 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain TPR_7 PF13176.6 EAQ84207.1 - 0.0046 16.9 1.9 4.5 7.5 0.1 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 EAQ84207.1 - 0.021 15.4 2.7 3.3 8.4 0.2 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3390 PF11870.8 EAQ84207.1 - 0.047 14.1 0.0 0.15 12.4 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3390) NRBF2_MIT PF17169.4 EAQ84207.1 - 0.048 13.9 0.1 1.3 9.3 0.0 3.2 2 0 0 2 2 2 0 MIT domain of nuclear receptor-binding factor 2 DUF3856 PF12968.7 EAQ84207.1 - 0.057 13.5 0.2 0.15 12.1 0.2 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF3856) AAA_22 PF13401.6 EAQ84207.1 - 0.079 13.2 0.0 0.24 11.7 0.0 1.9 1 1 0 1 1 1 0 AAA domain ATPase PF06745.13 EAQ84207.1 - 0.12 11.7 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 KaiC TPR_19 PF14559.6 EAQ84207.1 - 0.4 11.2 2.7 10 6.7 0.8 3.8 3 1 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.18 EAQ84207.1 - 0.43 10.7 3.6 8.6 6.5 0.2 3.2 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain NDC10_II PF16787.5 EAQ84209.1 - 7.1e-63 212.6 0.1 9.5e-63 212.1 0.1 1.1 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 GCR1_C PF12550.8 EAQ84209.1 - 6.5e-15 55.2 0.0 2.2e-14 53.5 0.0 2.0 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes PilJ PF13675.6 EAQ84209.1 - 0.037 14.0 2.6 0.081 13.0 0.7 2.5 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term HalX PF08663.10 EAQ84209.1 - 0.07 13.5 2.0 0.18 12.1 2.0 1.6 1 0 0 1 1 1 0 HalX domain RT_RNaseH PF17917.1 EAQ84210.1 - 3.3e-16 59.5 0.0 2.8e-15 56.5 0.0 2.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 EAQ84210.1 - 2e-13 50.4 0.0 3.5e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 EAQ84210.1 - 7.5e-12 45.2 0.0 1.2e-10 41.3 0.0 2.4 1 1 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Chromo PF00385.24 EAQ84210.1 - 2.1e-10 40.4 5.2 4.5e-10 39.3 5.2 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 EAQ84210.1 - 2.7e-09 37.3 0.0 7.5e-09 35.8 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 EAQ84210.1 - 1.4e-07 31.5 0.8 6.8e-07 29.3 0.6 2.4 2 0 0 2 2 2 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 EAQ84210.1 - 0.08 13.6 0.0 0.3 11.8 0.0 2.0 2 0 0 2 2 2 0 Aspartyl protease AT_hook PF02178.19 EAQ84210.1 - 1.8 8.7 6.7 8.1 6.7 6.7 2.2 1 0 0 1 1 1 0 AT hook motif Rxt3 PF08642.10 EAQ84212.1 - 1.8e-43 148.4 0.0 5.3e-43 146.8 0.0 1.9 1 0 0 1 1 1 1 Histone deacetylation protein Rxt3 LCCL PF03815.19 EAQ84212.1 - 7.9e-07 29.1 0.0 0.00042 20.4 0.0 2.4 2 0 0 2 2 2 2 LCCL domain Sugar_tr PF00083.24 EAQ84213.1 - 1.6e-120 403.0 19.8 1.9e-120 402.8 19.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EAQ84213.1 - 3.9e-20 72.1 35.8 6.9e-15 54.8 10.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Bromodomain PF00439.25 EAQ84216.1 - 2e-44 149.6 0.0 2e-22 79.1 0.1 3.0 3 0 0 3 3 3 2 Bromodomain BET PF17035.5 EAQ84216.1 - 1.9e-10 40.7 0.7 9.1e-10 38.6 0.9 2.1 2 0 0 2 2 2 1 Bromodomain extra-terminal - transcription regulation DUF3489 PF11994.8 EAQ84216.1 - 0.018 15.1 0.0 0.057 13.5 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3489) Utp12 PF04003.12 EAQ84217.1 - 5e-26 91.1 0.1 7.7e-26 90.5 0.1 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family TPR_12 PF13424.6 EAQ84219.1 - 2.8e-09 37.1 0.8 4.5e-05 23.7 0.1 2.8 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 EAQ84219.1 - 3.3e-06 26.8 0.7 1.9 8.8 0.1 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 EAQ84219.1 - 1.9e-05 24.4 2.2 0.12 12.4 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat Helo_like_N PF17111.5 EAQ84219.1 - 4.9e-05 22.8 0.0 9.5e-05 21.9 0.0 1.5 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins TPR_10 PF13374.6 EAQ84219.1 - 0.00027 20.7 0.5 2.5 8.1 0.1 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 EAQ84219.1 - 0.0028 17.7 0.2 10 6.6 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 EAQ84219.1 - 0.0088 15.8 1.7 2.3 8.2 0.1 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 EAQ84219.1 - 0.012 16.1 0.0 9.6 6.8 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-RVT PF13966.6 EAQ84221.1 - 0.028 15.1 0.1 0.12 13.1 0.0 2.1 2 0 0 2 2 2 0 zinc-binding in reverse transcriptase FAD_binding_3 PF01494.19 EAQ84222.1 - 6.2e-15 55.3 0.2 1.6e-06 27.6 0.0 3.4 3 1 0 3 3 3 2 FAD binding domain DAO PF01266.24 EAQ84222.1 - 8.3e-06 25.6 0.0 0.013 15.1 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EAQ84222.1 - 7.2e-05 22.9 0.0 0.00022 21.4 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EAQ84222.1 - 0.00095 18.5 0.0 0.0013 18.0 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DUF5428 PF17493.2 EAQ84222.1 - 0.0041 17.5 0.1 0.0075 16.7 0.1 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5428) Pyr_redox_3 PF13738.6 EAQ84222.1 - 0.022 14.1 0.0 0.03 13.6 0.0 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EAQ84222.1 - 0.038 13.2 0.0 0.061 12.6 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.12 EAQ84222.1 - 0.049 12.7 0.0 0.08 12.0 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Asp_Arg_Hydrox PF05118.15 EAQ84222.1 - 0.069 13.0 0.0 0.098 12.5 0.0 1.2 1 0 0 1 1 1 0 Aspartyl/Asparaginyl beta-hydroxylase Pyr_redox PF00070.27 EAQ84222.1 - 0.12 12.9 0.0 0.47 11.1 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Melibiase_2 PF16499.5 EAQ84223.1 - 5.1e-53 180.1 6.9 3.2e-52 177.5 6.9 2.0 1 1 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 EAQ84223.1 - 2.9e-07 30.5 0.0 1.1e-05 25.4 0.0 2.4 2 0 0 2 2 2 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 EAQ84223.1 - 1e-06 27.9 0.0 4.3e-06 25.9 0.0 1.9 2 0 0 2 2 2 1 Melibiase Aconitase PF00330.20 EAQ84224.1 - 3.8e-103 346.0 0.1 3e-102 343.0 0.1 2.0 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EAQ84224.1 - 2.2e-26 92.7 0.0 4.2e-26 91.8 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain MCM PF00493.23 EAQ84224.1 - 0.17 10.9 0.3 0.32 10.1 0.3 1.3 1 0 0 1 1 1 0 MCM P-loop domain Pkinase PF00069.25 EAQ84225.1 - 7.1e-31 107.5 0.0 1.2e-30 106.7 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ84225.1 - 2.4e-14 53.2 0.0 3.5e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EAQ84225.1 - 0.0043 15.9 0.0 0.0059 15.4 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase FHA PF00498.26 EAQ84225.1 - 0.011 16.1 0.0 0.039 14.3 0.0 2.0 1 0 0 1 1 1 0 FHA domain TraI PF07057.11 EAQ84225.1 - 0.16 12.1 0.0 0.36 11.0 0.0 1.5 1 0 0 1 1 1 0 DNA helicase TraI Lactonase PF10282.9 EAQ84227.1 - 4e-19 69.1 0.0 5.7e-19 68.6 0.0 1.3 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller C-C_Bond_Lyase PF15617.6 EAQ84227.1 - 0.097 11.8 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 C-C_Bond_Lyase of the TIM-Barrel fold MFS_1 PF07690.16 EAQ84228.1 - 3.5e-31 108.4 28.3 7.5e-16 58.0 8.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EAQ84228.1 - 0.00024 20.1 11.2 0.0082 15.0 3.9 2.2 1 1 1 2 2 2 2 MFS_1 like family OATP PF03137.20 EAQ84228.1 - 0.00054 18.4 8.6 0.14 10.4 0.2 3.4 3 0 0 3 3 3 3 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.24 EAQ84228.1 - 0.00055 18.9 5.7 0.00055 18.9 5.7 3.2 2 1 0 3 3 3 2 Sugar (and other) transporter MFS_2 PF13347.6 EAQ84228.1 - 0.016 13.8 21.1 0.015 13.9 8.4 3.2 2 2 0 2 2 2 0 MFS/sugar transport protein DUF3086 PF11285.8 EAQ84229.1 - 0.044 12.9 0.1 0.044 12.9 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3086) Msg2_C PF12373.8 EAQ84230.1 - 0.23 10.9 0.1 0.35 10.3 0.1 1.3 1 0 0 1 1 1 0 Major surface glycoprotein 2 C terminal PRKCSH PF07915.13 EAQ84231.1 - 4.1e-19 69.4 2.5 9.8e-19 68.1 0.0 2.5 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein AbiEi_4 PF13338.6 EAQ84231.1 - 0.03 14.5 0.1 0.15 12.2 0.0 2.1 2 0 0 2 2 2 0 Transcriptional regulator, AbiEi antitoxin DUF3169 PF11368.8 EAQ84233.1 - 0.017 14.7 0.0 0.022 14.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) Presenilin PF01080.17 EAQ84234.1 - 0.18 10.5 1.2 0.22 10.3 1.2 1.0 1 0 0 1 1 1 0 Presenilin His_Phos_1 PF00300.22 EAQ84235.1 - 1.1e-16 61.1 0.1 9.7e-16 58.0 0.1 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Macro PF01661.21 EAQ84236.1 - 0.016 15.3 0.0 0.031 14.3 0.0 1.5 1 0 0 1 1 1 0 Macro domain RVT_1 PF00078.27 EAQ84238.1 - 1.1e-40 139.5 0.0 1.7e-40 138.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 EAQ84238.1 - 1.8e-11 43.9 0.0 3.5e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 EAQ84238.1 - 4e-07 29.8 0.3 1.4e-06 28.0 0.3 2.0 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family PIF1 PF05970.14 EAQ84239.1 - 3e-32 112.2 0.0 7.7e-26 91.1 0.0 2.2 2 0 0 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 EAQ84239.1 - 2.7e-11 43.5 0.0 5.9e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAQ84239.1 - 3.1e-06 27.6 0.0 8.4e-06 26.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain Herpes_Helicase PF02689.14 EAQ84239.1 - 0.00042 18.4 0.0 0.033 12.1 0.0 2.1 2 0 0 2 2 2 2 Helicase F-box-like PF12937.7 EAQ84239.1 - 0.0058 16.5 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 F-box-like UvrD_C_2 PF13538.6 EAQ84239.1 - 0.0067 16.2 0.1 0.024 14.5 0.0 2.0 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain Torsin PF06309.11 EAQ84239.1 - 0.043 13.9 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 Torsin MFS_1 PF07690.16 EAQ84241.1 - 1.3e-32 113.1 52.3 1.3e-32 113.1 52.3 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EAQ84241.1 - 1.9e-05 23.7 14.6 1.9e-05 23.7 14.6 4.0 3 1 1 4 4 4 2 Sugar (and other) transporter TraL PF07178.11 EAQ84241.1 - 0.55 10.7 0.1 0.55 10.7 0.1 3.9 3 1 0 3 3 3 0 TraL protein Methyltransf_2 PF00891.18 EAQ84242.1 - 3.4e-19 69.0 0.0 1.6e-18 66.7 0.0 2.0 1 1 0 1 1 1 1 O-methyltransferase domain Methyltransf_25 PF13649.6 EAQ84242.1 - 9e-05 23.1 0.0 0.00029 21.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 EAQ84242.1 - 0.00072 19.1 0.0 0.0013 18.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 EAQ84242.1 - 0.013 14.8 0.0 0.03 13.7 0.0 1.6 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 EAQ84242.1 - 0.063 13.1 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 EAQ84242.1 - 0.18 12.6 0.0 0.38 11.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain PS-DH PF14765.6 EAQ84243.1 - 3.6e-67 226.7 0.9 3.6e-67 226.7 0.9 1.7 2 0 0 2 2 2 1 Polyketide synthase dehydratase ketoacyl-synt PF00109.26 EAQ84243.1 - 8.6e-64 215.5 0.0 1.6e-63 214.6 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 EAQ84243.1 - 3e-52 178.1 0.2 6.7e-52 177.0 0.2 1.6 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 EAQ84243.1 - 6.4e-48 163.0 0.0 1.7e-47 161.7 0.0 1.8 1 0 0 1 1 1 1 KR domain Ketoacyl-synt_C PF02801.22 EAQ84243.1 - 7.6e-31 106.6 0.0 4.2e-30 104.2 0.0 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 EAQ84243.1 - 7.6e-17 61.9 0.0 2.4e-16 60.3 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 EAQ84243.1 - 6.7e-14 52.3 2.8 1.5e-09 38.3 0.1 3.2 3 0 0 3 3 3 2 Ketoacyl-synthetase C-terminal extension Methyltransf_23 PF13489.6 EAQ84243.1 - 5.4e-11 42.6 0.0 2.9e-10 40.2 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain adh_short PF00106.25 EAQ84243.1 - 8.9e-11 41.6 0.1 5.4e-05 22.7 0.0 3.5 3 0 0 3 3 3 2 short chain dehydrogenase Methyltransf_11 PF08241.12 EAQ84243.1 - 3.6e-10 40.4 0.0 1.6e-09 38.3 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAQ84243.1 - 8.2e-10 39.3 0.0 4.2e-09 37.0 0.0 2.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAQ84243.1 - 3.1e-07 30.3 0.0 7.1e-07 29.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.6 EAQ84243.1 - 0.00014 22.9 0.1 0.0059 17.6 0.0 3.3 3 0 0 3 3 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EAQ84243.1 - 0.00015 21.6 0.2 0.00037 20.4 0.2 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EAQ84243.1 - 0.00035 20.5 0.6 0.0063 16.5 0.2 2.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ACP_syn_III PF08545.10 EAQ84243.1 - 0.00094 19.0 0.2 0.0029 17.4 0.2 1.9 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III adh_short_C2 PF13561.6 EAQ84243.1 - 0.0027 17.3 1.2 0.17 11.4 0.0 2.8 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Thiolase_N PF00108.23 EAQ84243.1 - 0.0038 16.6 0.4 0.011 15.2 0.1 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain FAD_binding_4 PF01565.23 EAQ84244.1 - 3.5e-20 72.2 9.1 5.3e-14 52.1 0.0 3.1 3 1 1 4 4 4 2 FAD binding domain BBE PF08031.12 EAQ84244.1 - 0.0013 18.7 0.5 0.003 17.6 0.5 1.6 1 0 0 1 1 1 1 Berberine and berberine like p450 PF00067.22 EAQ84245.1 - 5.3e-09 35.3 0.1 2.3e-07 30.0 0.0 2.3 2 1 0 2 2 2 2 Cytochrome P450 Cyto_heme_lyase PF01265.17 EAQ84245.1 - 0.038 13.6 0.3 0.057 13.0 0.3 1.2 1 0 0 1 1 1 0 Cytochrome c/c1 heme lyase DUF346 PF03984.13 EAQ84245.1 - 0.11 12.3 4.4 0.27 11.0 4.4 1.6 1 0 0 1 1 1 0 Repeat of unknown function (DUF346) Fungal_trans PF04082.18 EAQ84246.1 - 3.9e-05 22.8 1.1 0.00014 21.0 1.1 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.25 EAQ84248.1 - 3.7e-17 62.4 0.5 2.6e-14 53.1 0.2 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EAQ84248.1 - 3.2e-09 36.7 0.1 1e-08 35.1 0.1 1.7 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EAQ84248.1 - 1.3e-05 25.2 0.1 2.6e-05 24.2 0.1 1.5 1 1 0 1 1 1 1 KR domain Shikimate_DH PF01488.20 EAQ84248.1 - 0.038 14.1 0.0 0.074 13.1 0.0 1.5 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase AAA_12 PF13087.6 EAQ84249.1 - 1.5e-40 139.0 0.0 3.8e-40 137.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAQ84249.1 - 4.3e-28 98.8 18.5 8.9e-27 94.5 0.0 4.3 4 0 0 4 4 4 1 AAA domain AAA PF00004.29 EAQ84249.1 - 3.8e-26 92.1 0.0 3.3e-07 30.8 0.0 6.3 6 0 0 6 6 5 4 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 EAQ84249.1 - 2.7e-13 50.1 6.4 2.9e-07 30.4 0.0 4.8 5 0 0 5 5 4 3 AAA domain AAA_19 PF13245.6 EAQ84249.1 - 2.2e-11 44.3 0.0 1.8e-08 34.8 0.0 3.1 2 0 0 2 2 2 1 AAA domain AAA_lid_6 PF17866.1 EAQ84249.1 - 4.3e-08 33.2 0.7 8.2e-07 29.1 0.7 3.0 2 0 0 2 2 2 1 AAA lid domain AAA_5 PF07728.14 EAQ84249.1 - 0.00026 21.0 0.1 0.92 9.5 0.0 3.1 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 EAQ84249.1 - 0.00058 19.6 0.0 0.65 9.7 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein ResIII PF04851.15 EAQ84249.1 - 0.00083 19.4 0.0 0.11 12.5 0.0 3.6 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit RNA_helicase PF00910.22 EAQ84249.1 - 0.0025 18.2 0.0 1.1 9.7 0.0 3.2 3 0 0 3 3 2 1 RNA helicase Torsin PF06309.11 EAQ84249.1 - 0.0059 16.7 0.0 0.64 10.1 0.0 2.8 2 0 0 2 2 2 1 Torsin DUF2075 PF09848.9 EAQ84249.1 - 0.0096 15.2 9.5 0.065 12.5 0.0 4.9 5 0 0 5 5 4 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 EAQ84249.1 - 0.012 15.9 10.7 10 6.4 0.1 6.6 7 1 1 8 8 5 0 AAA domain AAA_24 PF13479.6 EAQ84249.1 - 0.029 14.1 0.3 4.8 6.9 0.0 3.4 3 0 0 3 3 3 0 AAA domain Mg_chelatase PF01078.21 EAQ84249.1 - 0.029 13.7 0.4 8.4 5.7 0.0 3.1 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 EAQ84249.1 - 0.062 12.9 1.2 1.5 8.3 0.1 3.2 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EAQ84249.1 - 0.075 13.6 0.7 32 5.1 0.1 3.6 3 0 0 3 3 2 0 AAA domain AAA_7 PF12775.7 EAQ84249.1 - 0.13 11.7 0.0 16 4.9 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_16 PF13191.6 EAQ84249.1 - 0.97 9.8 14.7 0.24 11.8 0.1 4.6 4 0 0 4 4 3 0 AAA ATPase domain FerA PF08165.11 EAQ84249.1 - 2.4 8.1 9.4 13 5.9 0.3 3.7 3 0 0 3 3 3 0 FerA (NUC095) domain V_ATPase_I PF01496.19 EAQ84249.1 - 5 4.9 10.5 12 3.6 10.5 1.6 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Asp PF00026.23 EAQ84250.1 - 0.071 12.5 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Eukaryotic aspartyl protease DUF1180 PF06679.12 EAQ84250.1 - 0.11 12.9 0.0 0.18 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Amino_oxidase PF01593.24 EAQ84251.1 - 1.8e-25 90.2 0.3 8.2e-19 68.2 0.2 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EAQ84251.1 - 0.00024 21.2 0.0 0.00067 19.8 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain TPP_enzyme_N PF02776.18 EAQ84253.1 - 2.4e-37 128.2 0.0 5.7e-37 127.0 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 EAQ84253.1 - 7.3e-09 35.5 0.1 5e-07 29.5 0.1 2.3 1 1 1 2 2 2 2 Thiamine pyrophosphate enzyme, central domain RVT_1 PF00078.27 EAQ84254.1 - 1.4e-38 132.7 0.0 1.2e-37 129.6 0.0 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) SET PF00856.28 EAQ84255.1 - 5e-10 40.0 0.0 2.7e-09 37.6 0.0 2.0 1 1 0 1 1 1 1 SET domain HeLo PF14479.6 EAQ84256.1 - 2.8e-49 167.8 0.0 4.3e-49 167.2 0.0 1.3 1 0 0 1 1 1 1 Prion-inhibition and propagation NACHT PF05729.12 EAQ84256.1 - 4.9e-10 39.6 0.1 2.4e-09 37.4 0.1 2.1 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EAQ84256.1 - 1.8e-06 28.4 0.0 1.4e-05 25.5 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain Viral_helicase1 PF01443.18 EAQ84256.1 - 0.0043 16.8 0.0 0.007 16.1 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.22 EAQ84256.1 - 0.0043 17.4 0.1 0.018 15.4 0.1 2.0 2 0 0 2 2 2 1 RNA helicase AAA_22 PF13401.6 EAQ84256.1 - 0.023 15.0 0.0 0.073 13.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 EAQ84256.1 - 0.037 13.2 0.0 0.077 12.2 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain ABC_tran PF00005.27 EAQ84256.1 - 0.039 14.5 0.1 0.085 13.4 0.1 1.5 1 0 0 1 1 1 0 ABC transporter AAA_30 PF13604.6 EAQ84256.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 EAQ84256.1 - 0.12 12.3 0.0 0.37 10.7 0.0 1.7 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Kdo PF06293.14 EAQ84257.1 - 0.0045 16.4 0.0 0.007 15.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PBCV_basic_adap PF08789.10 EAQ84258.1 - 1.2 9.3 13.1 2.2 8.5 0.5 3.0 3 0 0 3 3 3 0 PBCV-specific basic adaptor domain WW PF00397.26 EAQ84258.1 - 7.8 6.7 26.6 2 8.6 0.1 5.2 5 0 0 5 5 5 0 WW domain MFS_1 PF07690.16 EAQ84263.1 - 3e-35 121.8 29.9 4.1e-35 121.4 29.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Dimer_Tnp_hAT PF05699.14 EAQ84264.1 - 1.3e-15 56.9 0.0 4.7e-14 52.0 0.0 2.7 3 0 0 3 3 3 1 hAT family C-terminal dimerisation region zf-BED PF02892.15 EAQ84264.1 - 0.038 14.0 0.1 0.082 12.9 0.1 1.5 1 0 0 1 1 1 0 BED zinc finger Dimer_Tnp_hAT PF05699.14 EAQ84265.1 - 5.5e-17 61.3 0.1 9e-17 60.6 0.1 1.3 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-C2H2 PF00096.26 EAQ84265.1 - 0.17 12.4 1.2 1.1 9.9 0.5 2.3 2 0 0 2 2 2 0 Zinc finger, C2H2 type Asp PF00026.23 EAQ84266.1 - 1.1e-48 166.2 0.0 1.1e-48 166.2 0.0 1.7 2 0 0 2 2 2 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EAQ84266.1 - 6.1e-06 26.6 1.6 6.1e-06 26.6 1.6 3.8 2 2 0 2 2 2 1 Xylanase inhibitor N-terminal TFIIF_alpha PF05793.12 EAQ84266.1 - 0.87 8.1 9.9 1.4 7.4 9.9 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Rep_fac_C PF08542.11 EAQ84267.1 - 6e-18 65.0 0.0 2e-17 63.3 0.0 2.0 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.29 EAQ84267.1 - 4.4e-16 59.5 0.0 7.8e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 EAQ84267.1 - 1.4e-12 47.7 0.0 4.4e-12 46.1 0.0 1.8 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.15 EAQ84267.1 - 4.6e-08 33.2 0.0 9.6e-08 32.2 0.0 1.6 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_30 PF13604.6 EAQ84267.1 - 3.3e-07 30.2 0.1 1e-06 28.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_assoc_2 PF16193.5 EAQ84267.1 - 1.1e-06 28.9 0.1 3.5e-06 27.3 0.0 1.9 2 0 0 2 2 1 1 AAA C-terminal domain AAA_22 PF13401.6 EAQ84267.1 - 3.6e-06 27.3 0.0 1.2e-05 25.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EAQ84267.1 - 4.4e-06 27.2 0.0 2.1e-05 25.0 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_11 PF13086.6 EAQ84267.1 - 6.4e-06 26.1 0.1 0.00011 22.1 0.0 2.0 1 1 1 2 2 2 1 AAA domain AAA_3 PF07726.11 EAQ84267.1 - 7.3e-06 25.9 0.3 0.0015 18.4 0.1 2.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 EAQ84267.1 - 3.3e-05 23.7 0.0 7e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain DNA_pol3_delta PF06144.13 EAQ84267.1 - 6.1e-05 22.9 0.1 0.00011 22.0 0.1 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit DUF815 PF05673.13 EAQ84267.1 - 7.7e-05 22.0 0.0 0.00013 21.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 EAQ84267.1 - 0.00011 22.3 0.2 0.00032 20.7 0.2 1.9 1 1 1 2 2 2 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 EAQ84267.1 - 0.00025 21.1 0.0 0.00047 20.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAQ84267.1 - 0.00035 20.9 0.1 0.00086 19.7 0.1 1.7 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 EAQ84267.1 - 0.00043 20.1 0.0 0.0013 18.5 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activat PF00158.26 EAQ84267.1 - 0.00075 19.2 0.1 0.002 17.8 0.0 1.7 2 0 0 2 2 2 1 Sigma-54 interaction domain ResIII PF04851.15 EAQ84267.1 - 0.001 19.1 0.0 0.042 13.9 0.0 2.3 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit PhoH PF02562.16 EAQ84267.1 - 0.0018 17.8 0.9 0.96 8.9 0.0 2.7 2 1 1 3 3 3 2 PhoH-like protein AAA_18 PF13238.6 EAQ84267.1 - 0.0042 17.6 0.0 0.0073 16.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 EAQ84267.1 - 0.0047 17.2 0.0 0.0085 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain TniB PF05621.11 EAQ84267.1 - 0.006 16.0 0.0 0.046 13.1 0.0 2.2 1 1 0 1 1 1 1 Bacterial TniB protein AAA_7 PF12775.7 EAQ84267.1 - 0.014 14.9 0.0 0.028 13.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region DEAD PF00270.29 EAQ84267.1 - 0.021 14.6 0.4 0.15 11.8 0.1 2.4 2 1 1 3 3 3 0 DEAD/DEAH box helicase DUF2075 PF09848.9 EAQ84267.1 - 0.023 13.9 0.0 0.039 13.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ATPase_2 PF01637.18 EAQ84267.1 - 0.026 14.4 0.0 0.12 12.2 0.0 1.9 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea Mg_chelatase PF01078.21 EAQ84267.1 - 0.034 13.5 0.2 0.22 10.9 0.1 2.3 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 EAQ84267.1 - 0.047 13.3 0.0 0.14 11.7 0.0 1.8 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EAQ84267.1 - 0.079 13.4 0.0 0.17 12.3 0.0 1.7 1 1 0 1 1 1 0 RNA helicase UDPGT PF00201.18 EAQ84268.1 - 5.2e-11 42.0 0.0 9e-11 41.2 0.0 1.5 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_transf_4 PF13439.6 EAQ84268.1 - 0.051 13.6 0.0 0.096 12.7 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase Family 4 YAcAr PF10686.9 EAQ84268.1 - 0.11 12.5 0.6 3.2 7.8 0.0 3.1 3 1 1 4 4 4 0 YspA, cpYpsA-related SLOG family adh_short PF00106.25 EAQ84269.1 - 2.2e-27 95.8 0.3 1.3e-25 90.0 0.5 2.1 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EAQ84269.1 - 1.8e-16 60.5 0.1 5.4e-16 58.9 0.2 1.6 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EAQ84269.1 - 1.2e-06 28.6 0.2 2e-06 27.9 0.2 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EAQ84269.1 - 0.005 16.3 0.1 0.0084 15.6 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EAQ84269.1 - 0.033 13.3 0.0 0.073 12.2 0.0 1.5 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein Cnn_1N PF07989.11 EAQ84270.1 - 2.2e-10 40.6 6.1 4.4e-10 39.6 6.1 1.5 1 0 0 1 1 1 1 Centrosomin N-terminal motif 1 bZIP_1 PF00170.21 EAQ84270.1 - 7.7 6.7 10.9 10 6.3 0.2 3.3 2 1 1 3 3 3 0 bZIP transcription factor Glyco_hydro_47 PF01532.20 EAQ84271.1 - 9.4e-138 459.9 0.0 2.4e-133 445.4 0.0 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 47 Asp PF00026.23 EAQ84272.1 - 0.011 15.2 0.6 0.022 14.2 0.3 1.7 2 1 0 2 2 2 0 Eukaryotic aspartyl protease Syndecan PF01034.20 EAQ84272.1 - 0.028 14.3 0.0 0.053 13.4 0.0 1.3 1 0 0 1 1 1 0 Syndecan domain SKG6 PF08693.10 EAQ84272.1 - 0.029 13.8 3.4 0.058 12.8 3.4 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Gram_pos_anchor PF00746.21 EAQ84272.1 - 0.074 13.0 2.1 0.17 11.8 2.1 1.7 1 0 0 1 1 1 0 LPXTG cell wall anchor motif PTP_tm PF18861.1 EAQ84272.1 - 0.25 11.3 0.2 0.64 10.0 0.0 1.7 2 0 0 2 2 2 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J HEPN_RiboL-PSP PF18735.1 EAQ84273.1 - 0.021 14.7 0.0 0.036 14.0 0.0 1.4 1 0 0 1 1 1 0 RiboL-PSP-HEPN DUF829 PF05705.14 EAQ84276.1 - 4.9e-32 111.7 0.0 7.2e-32 111.2 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) KH_1 PF00013.29 EAQ84277.1 - 9.2e-31 105.5 3.3 9.8e-17 60.6 1.2 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 EAQ84277.1 - 1.2e-07 31.5 0.2 0.022 14.7 0.0 2.3 2 0 0 2 2 2 2 KH domain KH_2 PF07650.17 EAQ84277.1 - 7.8e-07 28.8 0.5 0.049 13.5 0.0 2.3 2 0 0 2 2 2 2 KH domain KH_5 PF13184.6 EAQ84277.1 - 0.065 13.3 0.3 3.6 7.8 0.1 2.3 2 0 0 2 2 2 0 NusA-like KH domain Asp PF00026.23 EAQ84278.1 - 8.4e-43 147.0 0.5 1.3e-42 146.3 0.5 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.6 EAQ84278.1 - 2.1e-06 28.3 0.0 1.7 9.3 0.0 3.5 3 0 0 3 3 3 3 Aspartyl protease TAXi_C PF14541.6 EAQ84278.1 - 3.2e-05 23.8 0.0 0.00021 21.1 0.0 2.3 3 0 0 3 3 3 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 EAQ84278.1 - 0.00013 22.4 0.0 3.4 8.3 0.0 3.5 3 0 0 3 3 3 2 gag-polyprotein putative aspartyl protease TAXi_N PF14543.6 EAQ84278.1 - 0.18 12.0 1.4 13 6.0 1.4 3.0 1 1 0 1 1 1 0 Xylanase inhibitor N-terminal DEAD PF00270.29 EAQ84279.1 - 1.3e-46 158.6 0.0 4.3e-46 156.9 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EAQ84279.1 - 6.7e-25 87.6 0.0 9e-24 84.0 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EAQ84279.1 - 5.9e-18 64.8 0.1 1.5e-17 63.6 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 EAQ84279.1 - 0.00055 20.0 0.0 0.0011 19.0 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 EAQ84279.1 - 0.004 16.5 1.4 0.65 9.3 0.0 2.5 2 0 0 2 2 2 2 U3-containing 90S pre-ribosomal complex subunit SecA_DEAD PF07517.14 EAQ84279.1 - 0.11 11.7 0.0 0.5 9.6 0.0 1.8 1 1 0 1 1 1 0 SecA DEAD-like domain Hce2 PF14856.6 EAQ84280.1 - 0.00043 20.5 0.6 0.0008 19.7 0.6 1.4 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor 6PF2K PF01591.18 EAQ84281.1 - 1.7e-78 263.0 0.1 2.3e-78 262.5 0.1 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 EAQ84281.1 - 4.6e-35 121.1 0.0 8.2e-35 120.3 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 EAQ84281.1 - 6.8e-07 29.5 0.0 1.2e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 EAQ84281.1 - 0.00049 19.6 0.0 0.00071 19.1 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 Zeta_toxin PF06414.12 EAQ84281.1 - 0.053 12.8 0.0 0.74 9.1 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin APS_kinase PF01583.20 EAQ84281.1 - 0.081 12.8 0.0 0.2 11.5 0.0 1.6 1 1 0 1 1 1 0 Adenylylsulphate kinase ApoLp-III PF07464.11 EAQ84282.1 - 0.0087 16.2 2.1 4.2 7.4 0.0 3.3 3 1 1 4 4 4 2 Apolipophorin-III precursor (apoLp-III) Baculo_PEP_C PF04513.12 EAQ84282.1 - 0.14 12.2 15.8 0.34 10.9 1.6 4.2 3 2 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus HsbA PF12296.8 EAQ84282.1 - 2.6 8.5 9.0 2.2 8.8 0.2 3.7 4 0 0 4 4 4 0 Hydrophobic surface binding protein A Trp_syntA PF00290.20 EAQ84283.1 - 8.2e-95 316.5 0.4 2e-94 315.3 0.0 1.8 2 0 0 2 2 2 1 Tryptophan synthase alpha chain PALP PF00291.25 EAQ84283.1 - 7.7e-50 170.0 1.7 1.6e-49 168.9 1.7 1.5 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PcrB PF01884.17 EAQ84283.1 - 0.14 11.6 0.1 1 8.8 0.1 2.2 2 0 0 2 2 2 0 PcrB family Ribosomal_L28 PF00830.19 EAQ84284.1 - 1.6e-20 73.0 1.9 2.4e-20 72.5 1.9 1.3 1 0 0 1 1 1 1 Ribosomal L28 family HAUS4 PF14735.6 EAQ84285.1 - 0.065 12.9 0.2 1 9.0 0.2 2.2 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 4 Aminotran_1_2 PF00155.21 EAQ84286.1 - 9e-35 120.5 0.0 1.1e-34 120.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II ADH_N PF08240.12 EAQ84288.1 - 2.9e-23 81.8 6.0 4.9e-23 81.1 6.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EAQ84288.1 - 3.6e-21 75.5 0.0 6.7e-21 74.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EAQ84288.1 - 1.5e-07 32.5 0.0 2.7e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EAQ84288.1 - 0.00069 19.0 0.1 0.0011 18.4 0.1 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 EAQ84288.1 - 0.0019 17.6 0.0 0.003 16.9 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 EAQ84288.1 - 0.0083 16.2 0.0 0.014 15.5 0.0 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_2 PF03446.15 EAQ84288.1 - 0.02 15.1 0.0 0.032 14.4 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase TrkA_N PF02254.18 EAQ84288.1 - 0.12 12.6 0.0 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain MFS_1 PF07690.16 EAQ84291.1 - 1.6e-23 83.2 26.5 1.6e-23 83.2 26.5 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily BT1 PF03092.16 EAQ84291.1 - 0.0064 14.8 2.0 0.012 13.9 2.0 1.4 1 0 0 1 1 1 1 BT1 family F-box PF00646.33 EAQ84292.1 - 2.6e-05 24.0 0.3 6.2e-05 22.8 0.3 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EAQ84292.1 - 0.05 13.5 0.5 0.16 11.9 0.1 2.1 2 0 0 2 2 2 0 F-box-like FAD_binding_4 PF01565.23 EAQ84293.1 - 1.2e-18 67.1 0.7 3.3e-18 65.8 0.7 1.8 1 0 0 1 1 1 1 FAD binding domain MFS_1 PF07690.16 EAQ84293.1 - 2e-08 33.6 25.4 4.1e-08 32.5 25.4 1.5 1 0 0 1 1 1 1 Major Facilitator Superfamily BBE PF08031.12 EAQ84293.1 - 2.5e-06 27.5 0.2 6.3e-06 26.2 0.2 1.6 1 0 0 1 1 1 1 Berberine and berberine like Pax2_C PF12403.8 EAQ84293.1 - 0.088 12.9 0.2 0.24 11.5 0.0 1.8 2 0 0 2 2 2 0 Paired-box protein 2 C terminal DUF1431 PF07248.12 EAQ84294.1 - 0.00032 21.0 4.2 0.00044 20.5 4.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1431) DUF2282 PF10048.9 EAQ84294.1 - 0.021 14.8 3.0 1.1 9.3 0.0 3.5 1 1 2 3 3 3 0 Predicted integral membrane protein (DUF2282) hEGF PF12661.7 EAQ84294.1 - 0.08 13.6 5.2 1.1 10.0 1.6 3.0 1 1 2 3 3 3 0 Human growth factor-like EGF PIF1 PF05970.14 EAQ84295.1 - 1.6e-17 63.8 0.1 2.8e-17 62.9 0.1 1.3 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 EAQ84295.1 - 2.1e-05 24.4 0.0 0.0001 22.1 0.0 2.1 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.6 EAQ84295.1 - 0.068 13.5 0.2 0.31 11.4 0.2 2.0 1 1 0 1 1 1 0 AAA domain PIF1 PF05970.14 EAQ84297.1 - 7.4e-07 28.7 0.1 1.2e-06 27.9 0.1 1.2 1 0 0 1 1 1 1 PIF1-like helicase Exo_endo_phos_2 PF14529.6 EAQ84299.1 - 1.3e-22 79.8 0.1 6.5e-22 77.6 0.1 2.2 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 EAQ84299.1 - 0.00011 21.9 0.3 0.00045 19.8 0.2 2.1 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family zf-RVT PF13966.6 EAQ84299.1 - 0.09 13.5 0.4 0.71 10.6 0.1 2.8 2 0 0 2 2 2 0 zinc-binding in reverse transcriptase zf-CCHC PF00098.23 EAQ84299.1 - 0.13 12.4 1.4 0.26 11.4 1.4 1.5 1 0 0 1 1 1 0 Zinc knuckle Tannase PF07519.11 EAQ84300.1 - 7.4e-86 288.9 0.0 8.3e-86 288.7 0.0 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.21 EAQ84300.1 - 0.0004 19.9 0.0 0.03 13.8 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 EAQ84300.1 - 0.046 13.4 0.2 0.15 11.7 0.1 1.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold Esterase PF00756.20 EAQ84300.1 - 0.1 12.2 0.1 0.19 11.4 0.1 1.3 1 0 0 1 1 1 0 Putative esterase Methyltransf_25 PF13649.6 EAQ84301.1 - 1.9e-05 25.3 0.0 8.8e-05 23.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EAQ84301.1 - 0.00011 22.8 0.0 0.00048 20.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 EAQ84301.1 - 0.047 13.4 0.0 0.069 12.9 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_11 PF08241.12 EAQ84301.1 - 0.062 14.0 0.0 0.19 12.4 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 EAQ84301.1 - 0.071 12.9 0.0 0.18 11.6 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain Tymo_coat PF00983.18 EAQ84301.1 - 0.12 12.2 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Tymovirus coat protein PIF1 PF05970.14 EAQ84302.1 - 1.4e-28 100.1 0.0 2.1e-28 99.6 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase Helitron_like_N PF14214.6 EAQ84302.1 - 6.6e-24 85.2 1.4 1.1e-19 71.4 0.1 2.3 1 1 1 2 2 2 2 Helitron helicase-like domain at N-terminus AAA_30 PF13604.6 EAQ84302.1 - 5.3e-09 36.1 0.0 1.1e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAQ84302.1 - 3.6e-07 30.6 0.0 7.3e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain Nif11 PF07862.11 EAQ84302.1 - 0.05 13.9 0.0 0.13 12.6 0.0 1.8 1 0 0 1 1 1 0 Nif11 domain AAA_11 PF13086.6 EAQ84302.1 - 0.078 12.8 0.0 14 5.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain Torsin PF06309.11 EAQ84302.1 - 0.087 12.9 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Torsin Esterase_phd PF10503.9 EAQ84303.1 - 9.1e-22 77.6 0.7 1.3e-21 77.1 0.7 1.2 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 EAQ84303.1 - 5.9e-07 29.2 0.7 1e-06 28.4 0.7 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 EAQ84303.1 - 0.0015 18.2 1.2 0.0053 16.4 0.9 2.0 1 1 1 2 2 2 1 Putative esterase COesterase PF00135.28 EAQ84303.1 - 0.011 14.6 0.0 0.021 13.7 0.0 1.5 1 0 0 1 1 1 0 Carboxylesterase family Abhydrolase_3 PF07859.13 EAQ84303.1 - 0.034 14.0 0.1 0.053 13.4 0.1 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Cellulase PF00150.18 EAQ84304.1 - 1.8e-17 63.7 7.6 3e-17 63.0 7.6 1.3 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.17 EAQ84304.1 - 4.1e-06 26.1 0.0 3.9e-05 22.9 0.0 2.3 2 1 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_42 PF02449.15 EAQ84304.1 - 0.00014 21.3 0.0 0.00045 19.7 0.0 1.9 1 1 0 1 1 1 1 Beta-galactosidase CBM_20 PF00686.19 EAQ84305.1 - 7.4e-34 115.5 0.7 1.3e-33 114.8 0.7 1.4 1 0 0 1 1 1 1 Starch binding domain LPMO_10 PF03067.15 EAQ84305.1 - 3e-07 31.3 0.1 5.2e-07 30.5 0.1 1.5 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading ATPgrasp_N PF18130.1 EAQ84306.1 - 7.4e-15 55.3 0.0 1.5e-14 54.3 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp N-terminal domain ATP-grasp_4 PF13535.6 EAQ84306.1 - 1.1e-07 31.6 0.0 9.9e-06 25.2 0.0 2.6 2 0 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 EAQ84306.1 - 1.1e-05 25.1 0.0 2.3e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 EAQ84306.1 - 0.00012 22.2 0.0 0.0025 17.9 0.0 2.3 2 0 0 2 2 2 1 ATP-grasp domain CPSase_L_D2 PF02786.17 EAQ84306.1 - 0.0027 17.2 0.0 0.0054 16.3 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain GARS_A PF01071.19 EAQ84306.1 - 0.036 13.8 0.0 0.059 13.1 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RimK PF08443.11 EAQ84306.1 - 0.13 11.9 0.0 0.29 10.7 0.0 1.5 1 0 0 1 1 1 0 RimK-like ATP-grasp domain Rossmann-like PF10727.9 EAQ84306.1 - 0.16 11.8 0.1 0.69 9.8 0.0 2.0 2 0 0 2 2 2 0 Rossmann-like domain HMGL-like PF00682.19 EAQ84307.1 - 4.6e-59 200.1 0.0 8.1e-59 199.3 0.0 1.4 1 1 0 1 1 1 1 HMGL-like Ank_2 PF12796.7 EAQ84308.1 - 1e-33 115.8 3.3 1.2e-17 64.3 0.2 3.2 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAQ84308.1 - 2.4e-28 98.1 2.6 3e-11 43.6 0.1 4.1 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAQ84308.1 - 2.2e-24 82.9 0.6 2.7e-05 24.2 0.0 4.4 4 0 0 4 4 4 4 Ankyrin repeat Ank PF00023.30 EAQ84308.1 - 3.5e-24 84.1 2.5 1.4e-06 28.4 0.1 4.7 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 EAQ84308.1 - 1.7e-17 63.2 1.0 3.2e-05 24.1 0.1 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) bZIP_1 PF00170.21 EAQ84308.1 - 5.2e-06 26.5 4.1 8.3e-06 25.8 4.1 1.3 1 0 0 1 1 1 1 bZIP transcription factor VWA_3_C PF18571.1 EAQ84308.1 - 0.0021 17.9 1.5 1 9.3 0.0 3.3 3 0 0 3 3 3 2 von Willebrand factor type A C-terminal domain bZIP_2 PF07716.15 EAQ84308.1 - 0.0057 16.7 7.7 0.0095 16.0 7.7 1.3 1 0 0 1 1 1 1 Basic region leucine zipper ABC_membrane PF00664.23 EAQ84309.1 - 2.6e-59 201.1 31.7 9.7e-43 146.8 17.1 3.1 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 EAQ84309.1 - 2e-57 193.5 0.4 2.7e-31 108.9 0.0 3.4 2 1 1 3 3 3 3 ABC transporter SMC_N PF02463.19 EAQ84309.1 - 7.5e-16 58.2 4.9 2.3e-06 27.2 0.1 5.1 4 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EAQ84309.1 - 2e-11 44.6 2.4 0.00012 22.5 0.1 2.9 2 1 0 2 2 2 2 AAA ATPase domain AAA_30 PF13604.6 EAQ84309.1 - 3e-10 40.2 0.7 0.00075 19.3 0.2 2.9 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.6 EAQ84309.1 - 9.6e-10 38.9 0.1 0.0015 18.8 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_21 PF13304.6 EAQ84309.1 - 2.6e-08 34.0 0.2 0.31 10.8 0.0 4.2 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EAQ84309.1 - 5.2e-08 33.0 0.1 0.016 15.2 0.0 2.9 2 1 1 3 3 3 2 RsgA GTPase AAA_29 PF13555.6 EAQ84309.1 - 5.8e-08 32.4 0.0 0.01 15.6 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.6 EAQ84309.1 - 9.8e-07 28.8 0.0 0.0035 17.1 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA PF00004.29 EAQ84309.1 - 2.2e-06 28.1 0.1 0.037 14.4 0.0 3.6 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) ABC_ATPase PF09818.9 EAQ84309.1 - 1.3e-05 24.3 0.7 0.12 11.1 0.0 2.8 3 0 0 3 3 3 2 Predicted ATPase of the ABC class Zeta_toxin PF06414.12 EAQ84309.1 - 1.8e-05 24.1 0.7 0.096 11.9 0.0 3.3 3 0 0 3 3 3 2 Zeta toxin TniB PF05621.11 EAQ84309.1 - 1.8e-05 24.2 0.0 0.0048 16.3 0.0 2.7 3 0 0 3 3 3 1 Bacterial TniB protein AAA_23 PF13476.6 EAQ84309.1 - 1.8e-05 25.3 0.1 0.31 11.5 0.0 2.3 2 0 0 2 2 2 2 AAA domain Rad17 PF03215.15 EAQ84309.1 - 8.9e-05 22.5 0.0 0.009 15.9 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain G-alpha PF00503.20 EAQ84309.1 - 0.00013 21.3 0.0 0.38 9.9 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit AAA_5 PF07728.14 EAQ84309.1 - 0.00013 21.9 0.1 0.68 9.9 0.0 3.5 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 EAQ84309.1 - 0.00021 21.5 0.1 0.52 10.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 EAQ84309.1 - 0.00041 20.1 0.0 1.1 9.0 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 EAQ84309.1 - 0.00064 19.3 0.0 1.1 8.8 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_25 PF13481.6 EAQ84309.1 - 0.00079 19.0 0.0 1.6 8.3 0.0 2.8 3 0 0 3 3 2 2 AAA domain ATP-synt_ab PF00006.25 EAQ84309.1 - 0.0015 18.3 1.3 2.8 7.6 0.0 3.6 3 1 0 3 3 3 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_18 PF13238.6 EAQ84309.1 - 0.0015 19.1 0.0 2.1 8.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 EAQ84309.1 - 0.0022 18.3 0.1 2.9 8.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.6 EAQ84309.1 - 0.0022 18.2 5.6 0.99 9.7 0.4 3.8 3 1 0 3 3 2 2 Putative exonuclease SbcCD, C subunit IstB_IS21 PF01695.17 EAQ84309.1 - 0.0032 17.2 0.3 0.95 9.2 0.0 3.5 4 0 0 4 4 4 1 IstB-like ATP binding protein PRK PF00485.18 EAQ84309.1 - 0.012 15.3 0.0 2.4 7.8 0.0 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family RNA_helicase PF00910.22 EAQ84309.1 - 0.02 15.3 0.1 7.6 7.0 0.0 3.0 3 0 0 3 3 2 0 RNA helicase Cytidylate_kin PF02224.18 EAQ84309.1 - 0.021 14.6 0.3 3.3 7.4 0.0 3.0 3 0 0 3 3 3 0 Cytidylate kinase AAA_14 PF13173.6 EAQ84309.1 - 0.028 14.4 0.0 6.7 6.7 0.0 3.2 3 1 0 3 3 3 0 AAA domain DUF87 PF01935.17 EAQ84309.1 - 0.034 14.2 0.0 3.3 7.7 0.0 2.7 2 0 0 2 2 2 0 Helicase HerA, central domain MMR_HSR1 PF01926.23 EAQ84309.1 - 0.039 14.0 0.9 15 5.7 0.3 3.5 3 1 0 3 3 2 0 50S ribosome-binding GTPase ECH_2 PF16113.5 EAQ84309.1 - 0.046 13.2 3.7 0.9 9.0 0.1 3.0 3 0 0 3 3 3 0 Enoyl-CoA hydratase/isomerase NB-ARC PF00931.22 EAQ84309.1 - 0.055 12.7 0.0 3.6 6.7 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain APS_kinase PF01583.20 EAQ84309.1 - 0.067 13.1 0.1 14 5.6 0.0 2.8 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_PrkA PF08298.11 EAQ84309.1 - 0.18 10.7 0.1 15 4.4 0.0 2.3 2 0 0 2 2 2 0 PrkA AAA domain NACHT PF05729.12 EAQ84309.1 - 0.24 11.3 0.5 14 5.5 0.0 2.9 3 0 0 3 3 3 0 NACHT domain Aconitase PF00330.20 EAQ84310.1 - 3.8e-77 260.3 0.0 4.5e-77 260.0 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EAQ84310.1 - 4.7e-32 111.1 0.0 7.5e-32 110.4 0.0 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain MFS_1 PF07690.16 EAQ84311.1 - 3.7e-19 68.9 42.9 1.5e-12 47.1 8.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 EAQ84311.1 - 0.00072 18.9 25.9 0.0032 16.8 25.8 1.9 1 1 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB Dpy19 PF10034.9 EAQ84311.1 - 0.0036 15.6 0.0 0.013 13.7 0.0 1.8 1 1 0 1 1 1 1 Q-cell neuroblast polarisation DUF2243 PF10002.9 EAQ84311.1 - 0.85 9.7 9.3 0.17 12.0 0.9 3.3 3 1 0 3 3 3 0 Predicted membrane protein (DUF2243) 2OG-FeII_Oxy PF03171.20 EAQ84312.1 - 1.4e-10 41.6 0.0 4.9e-10 39.8 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 EAQ84312.1 - 1.3e-08 35.6 0.4 1.1e-06 29.4 0.4 2.3 1 1 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal p450 PF00067.22 EAQ84313.1 - 1.2e-32 113.3 0.0 1.5e-32 113.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF4351 PF14261.6 EAQ84313.1 - 0.31 11.1 2.9 14 5.8 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4351) DUF4174 PF13778.6 EAQ84314.1 - 0.023 15.2 0.0 0.046 14.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4174) 7tm_4 PF13853.6 EAQ84314.1 - 0.064 13.0 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Olfactory receptor Transferase PF02458.15 EAQ84316.1 - 2.8e-15 55.9 0.0 3.9e-15 55.4 0.0 1.1 1 0 0 1 1 1 1 Transferase family eIF3g PF12353.8 EAQ84317.1 - 0.002 18.5 0.6 0.0069 16.8 0.6 1.9 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G DUF2113 PF09886.9 EAQ84317.1 - 0.063 12.6 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2113) RVT_2 PF07727.14 EAQ84318.1 - 8.1e-39 133.7 0.2 6.6e-38 130.7 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 EAQ84318.1 - 5.8e-12 45.9 0.0 6.5e-11 42.5 0.0 2.5 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.6 EAQ84318.1 - 8.7e-08 31.9 0.1 1.8e-07 30.9 0.1 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain RVT_1 PF00078.27 EAQ84318.1 - 0.16 11.5 0.0 0.29 10.6 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 EAQ84319.1 - 2.1e-29 102.7 0.0 3.2e-29 102.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 EAQ84319.1 - 1.6e-09 37.6 0.3 4e-09 36.4 0.1 1.8 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase CDC45 PF02724.14 EAQ84320.1 - 7.2 4.8 5.1 11 4.1 5.1 1.1 1 0 0 1 1 1 0 CDC45-like protein RVT_1 PF00078.27 EAQ84321.1 - 6.4e-32 110.9 0.0 4.9e-31 108.0 0.0 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 EAQ84321.1 - 0.11 13.3 0.0 0.36 11.6 0.0 1.9 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase Pyr_redox_2 PF07992.14 EAQ84323.1 - 2.1e-47 161.8 2.8 3.5e-47 161.0 2.8 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase p450 PF00067.22 EAQ84323.1 - 1.1e-45 156.3 0.0 1.7e-45 155.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Pyr_redox PF00070.27 EAQ84323.1 - 7.8e-12 45.6 2.7 1.8e-11 44.5 0.6 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Reductase_C PF14759.6 EAQ84323.1 - 3.7e-06 27.4 0.1 1.1e-05 25.9 0.1 1.8 1 0 0 1 1 1 1 Reductase C-terminal NAD_binding_9 PF13454.6 EAQ84323.1 - 0.018 15.0 0.1 10 6.1 0.0 2.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding Beta_propel PF09826.9 EAQ84324.1 - 0.027 13.4 0.0 0.35 9.7 0.1 2.0 1 1 2 3 3 3 0 Beta propeller domain DUF1989 PF09347.10 EAQ84325.1 - 2.6e-61 206.1 0.0 3.6e-61 205.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) Abhydrolase_3 PF07859.13 EAQ84326.1 - 1.2e-14 54.7 0.0 1.3e-14 54.5 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Polysacc_lyase PF14099.6 EAQ84327.1 - 8.5e-51 172.8 0.6 9.8e-51 172.6 0.6 1.0 1 0 0 1 1 1 1 Polysaccharide lyase Sugar_tr PF00083.24 EAQ84328.1 - 1.4e-80 271.4 24.5 1.7e-80 271.1 24.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EAQ84328.1 - 2.7e-25 89.0 25.3 1.5e-22 80.0 16.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EAQ84328.1 - 0.00013 20.6 2.0 0.00019 20.0 2.0 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Exo_endo_phos_2 PF14529.6 EAQ84331.1 - 8.6e-09 35.3 0.0 3.8e-08 33.2 0.0 2.1 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase RVT_1 PF00078.27 EAQ84332.1 - 1.4e-19 70.5 0.0 1.7e-13 50.7 0.0 2.8 2 1 1 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) UreE_N PF02814.15 EAQ84332.1 - 0.039 13.5 0.2 0.38 10.4 0.0 2.5 2 0 0 2 2 2 0 UreE urease accessory protein, N-terminal domain RVT_2 PF07727.14 EAQ84333.1 - 3.5e-27 95.6 0.0 2.1e-26 93.0 0.0 2.1 3 0 0 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 EAQ84333.1 - 0.00032 20.3 0.0 0.0007 19.2 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 EAQ84334.1 - 6.2e-38 130.5 0.0 3.7e-37 128.0 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 EAQ84334.1 - 0.0019 18.2 1.7 0.0019 18.2 1.7 2.6 2 0 0 2 2 2 1 Zinc knuckle M20_dimer PF07687.14 EAQ84335.1 - 0.0046 16.8 0.0 0.0099 15.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain 2OG-FeII_Oxy PF03171.20 EAQ84337.1 - 5.8e-15 55.6 0.0 1e-14 54.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 EAQ84337.1 - 4e-11 43.7 0.0 7.3e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal DUF3712 PF12505.8 EAQ84338.1 - 6.6e-28 97.5 0.1 1.1e-27 96.8 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3712) MULE PF10551.9 EAQ84339.1 - 1.1e-17 64.2 0.5 2e-11 44.2 0.1 2.7 1 1 1 2 2 2 2 MULE transposase domain Hamartin PF04388.12 EAQ84339.1 - 3.2 6.3 10.5 6 5.4 10.5 1.3 1 0 0 1 1 1 0 Hamartin protein Hce2 PF14856.6 EAQ84340.1 - 1.9e-22 79.5 0.0 3e-22 78.8 0.0 1.3 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor LIN52 PF10044.9 EAQ84341.1 - 0.015 16.0 0.0 7.2 7.4 0.0 4.4 4 2 2 6 6 6 0 Retinal tissue protein YqfQ PF14181.6 EAQ84341.1 - 0.12 12.6 0.4 96 3.1 0.0 4.0 4 1 0 4 4 4 0 YqfQ-like protein CRAL_TRIO PF00650.20 EAQ84342.1 - 3.7e-40 137.2 0.1 6.4e-40 136.5 0.1 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EAQ84342.1 - 7.8e-15 54.8 0.5 3e-14 52.9 0.3 2.2 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 EAQ84342.1 - 2.3e-07 31.0 0.0 3.7e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Abhydrolase_3 PF07859.13 EAQ84343.1 - 1.6e-28 100.1 0.0 2.7e-28 99.3 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Pyr_redox_3 PF13738.6 EAQ84343.1 - 1.8e-11 43.9 0.1 5.6e-11 42.3 0.0 1.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 EAQ84343.1 - 3e-10 39.1 0.0 1.5e-09 36.8 0.0 1.8 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Say1_Mug180 PF10340.9 EAQ84343.1 - 6.3e-10 38.4 0.0 6.6e-09 35.1 0.0 2.5 3 0 0 3 3 3 1 Steryl acetyl hydrolase NAD_binding_8 PF13450.6 EAQ84343.1 - 1.3e-08 34.9 0.0 1.8e-06 28.0 0.0 2.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EAQ84343.1 - 1.9e-07 30.6 0.0 1.1e-06 28.1 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EAQ84343.1 - 2e-05 23.9 0.2 9.4e-05 21.7 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 EAQ84343.1 - 8.6e-05 21.9 0.0 0.0041 16.4 0.0 2.3 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 EAQ84343.1 - 0.0016 18.1 4.3 0.006 16.2 0.7 3.1 4 0 0 4 4 4 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EAQ84343.1 - 0.0016 18.9 0.3 0.15 12.7 0.0 3.0 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 EAQ84343.1 - 0.0099 15.2 0.0 0.016 14.5 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 EAQ84343.1 - 0.057 12.5 2.1 0.29 10.2 0.1 2.6 3 0 0 3 3 3 0 FAD binding domain Shikimate_DH PF01488.20 EAQ84343.1 - 0.068 13.2 0.0 0.2 11.7 0.0 1.7 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Mqo PF06039.15 EAQ84343.1 - 0.14 10.7 0.0 0.28 9.7 0.0 1.5 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) adh_short PF00106.25 EAQ84344.1 - 8.6e-42 142.8 0.1 2.1e-41 141.5 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EAQ84344.1 - 5.8e-32 111.1 0.0 7.7e-32 110.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EAQ84344.1 - 2.4e-09 37.4 1.2 1e-08 35.3 1.2 1.8 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EAQ84344.1 - 2.6e-05 23.8 0.0 3.3e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EAQ84344.1 - 0.00016 20.8 0.0 0.00022 20.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 EAQ84344.1 - 0.0034 17.3 0.1 0.0067 16.3 0.1 1.6 1 1 0 1 1 1 1 NAD(P)H-binding DUF1776 PF08643.10 EAQ84344.1 - 0.037 13.4 0.1 0.056 12.8 0.1 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Fungal_trans_2 PF11951.8 EAQ84345.1 - 7.8e-08 31.5 0.2 1.3e-07 30.7 0.2 1.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain p450 PF00067.22 EAQ84346.1 - 4.5e-78 263.1 0.0 5.5e-78 262.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_3 PF01494.19 EAQ84347.1 - 8.6e-80 268.6 0.0 1.2e-79 268.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 EAQ84347.1 - 0.0039 16.3 2.5 0.048 12.8 1.0 2.3 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 EAQ84347.1 - 0.0044 16.3 0.0 0.0088 15.3 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EAQ84347.1 - 0.0077 15.8 0.3 0.049 13.2 0.5 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EAQ84347.1 - 0.018 15.2 1.5 0.038 14.2 1.5 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EAQ84347.1 - 0.05 14.2 0.0 0.5 11.0 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EAQ84347.1 - 0.061 12.4 0.3 0.11 11.5 0.3 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Crystall_3 PF08964.10 EAQ84347.1 - 0.13 12.4 0.1 1.3 9.2 0.0 2.2 2 0 0 2 2 2 0 Beta/Gamma crystallin DUF1889 PF08986.10 EAQ84347.1 - 0.15 12.4 0.0 6.7 7.2 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1889) Thi4 PF01946.17 EAQ84347.1 - 0.27 10.4 0.2 0.5 9.6 0.2 1.3 1 0 0 1 1 1 0 Thi4 family RVT_1 PF00078.27 EAQ84348.1 - 5.2e-17 62.1 0.0 8.2e-17 61.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_3 PF13456.6 EAQ84348.1 - 0.00046 20.0 0.0 0.0011 18.7 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase-like zf-RVT PF13966.6 EAQ84348.1 - 0.0064 17.2 0.2 0.029 15.1 0.2 2.1 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase GCSF PF16647.5 EAQ84348.1 - 0.038 13.8 0.0 0.084 12.7 0.0 1.6 1 0 0 1 1 1 0 Granulocyte colony-stimulating factor MARVEL PF01284.23 EAQ84349.1 - 0.064 13.3 19.9 0.14 12.2 19.9 1.5 1 1 0 1 1 1 0 Membrane-associating domain ADH_N PF08240.12 EAQ84351.1 - 4.3e-24 84.5 0.5 7.6e-24 83.7 0.5 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_assoc PF13823.6 EAQ84351.1 - 1.4e-10 40.8 1.4 1.4e-10 40.8 1.4 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-associated ADH_zinc_N PF00107.26 EAQ84351.1 - 1.5e-07 31.4 0.5 2.5e-05 24.3 0.0 2.9 3 0 0 3 3 3 2 Zinc-binding dehydrogenase Lipase_3 PF01764.25 EAQ84352.1 - 7e-06 26.0 0.0 2.2e-05 24.3 0.0 1.7 1 1 1 2 2 2 1 Lipase (class 3) Rft-1 PF04506.13 EAQ84354.1 - 7.1e-133 444.0 0.6 9.5e-133 443.6 0.6 1.1 1 0 0 1 1 1 1 Rft protein Ldi PF18566.1 EAQ84354.1 - 1.4e-93 313.9 1.0 6.2e-68 229.6 0.7 2.2 1 1 1 2 2 2 2 Linalool dehydratase/isomerase Polysacc_synt PF01943.17 EAQ84354.1 - 1.5e-07 31.1 5.4 1.5e-07 31.1 5.4 2.5 3 0 0 3 3 3 1 Polysaccharide biosynthesis protein Polysacc_synt_3 PF13440.6 EAQ84354.1 - 0.005 16.1 14.4 0.0083 15.4 0.1 3.0 3 0 0 3 3 3 2 Polysaccharide biosynthesis protein DEAD PF00270.29 EAQ84356.1 - 9.9e-48 162.2 0.0 6.7e-47 159.5 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EAQ84356.1 - 1.8e-34 118.4 0.0 1.3e-31 109.2 0.1 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain UTP25 PF06862.12 EAQ84356.1 - 0.071 11.9 0.0 0.19 10.4 0.0 1.7 1 0 0 1 1 1 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 CMS1 PF14617.6 EAQ84356.1 - 0.94 8.8 0.0 0.94 8.8 0.0 3.5 2 1 1 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit GREB1 PF15782.5 EAQ84356.1 - 9.2 3.2 11.0 12 2.9 11.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer RNase_H PF00075.24 EAQ84359.1 - 9.4e-38 129.6 0.0 1.5e-37 128.9 0.0 1.3 1 0 0 1 1 1 1 RNase H Cauli_VI PF01693.16 EAQ84359.1 - 1.6e-36 124.3 13.0 1e-18 67.3 2.8 2.4 2 0 0 2 2 2 2 Caulimovirus viroplasmin TRP PF06011.12 EAQ84360.1 - 6.7e-157 522.6 32.0 7.9e-157 522.3 32.0 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 EAQ84360.1 - 9.3e-43 145.9 0.3 1.5e-42 145.2 0.3 1.4 1 0 0 1 1 1 1 ML-like domain LapA_dom PF06305.11 EAQ84360.1 - 0.0013 18.5 0.1 0.0013 18.5 0.1 3.2 3 0 0 3 3 3 1 Lipopolysaccharide assembly protein A domain DUF4579 PF15158.6 EAQ84360.1 - 0.61 9.8 5.6 0.4 10.4 0.1 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4579) Ank_2 PF12796.7 EAQ84361.1 - 2.8e-12 47.1 0.2 1.1e-06 29.2 0.0 4.7 2 2 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAQ84361.1 - 3.4e-11 43.1 3.5 0.022 15.0 0.0 5.1 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAQ84361.1 - 6.5e-10 38.4 2.9 0.25 12.0 0.0 5.8 6 0 0 6 6 6 3 Ankyrin repeat Ank PF00023.30 EAQ84361.1 - 6.2e-07 29.6 7.9 0.056 13.9 0.1 5.1 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 EAQ84361.1 - 6.3e-07 29.8 0.2 0.0099 16.4 0.0 4.7 3 2 2 5 5 5 2 Ankyrin repeats (many copies) F-box PF00646.33 EAQ84361.1 - 0.0007 19.4 0.1 0.0007 19.4 0.1 1.9 2 0 0 2 2 2 1 F-box domain S1FA PF04689.13 EAQ84362.1 - 0.068 13.3 0.4 0.12 12.5 0.4 1.3 1 0 0 1 1 1 0 DNA binding protein S1FA SKG6 PF08693.10 EAQ84362.1 - 0.14 11.6 1.8 0.28 10.6 1.8 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Syndecan PF01034.20 EAQ84362.1 - 0.43 10.5 1.4 0.7 9.9 1.4 1.2 1 0 0 1 1 1 0 Syndecan domain Podoplanin PF05808.11 EAQ84362.1 - 0.93 9.6 3.6 0.24 11.5 0.3 1.7 2 0 0 2 2 2 0 Podoplanin HORMA PF02301.18 EAQ84363.1 - 4.4e-35 121.2 0.0 5.1e-35 121.0 0.0 1.0 1 0 0 1 1 1 1 HORMA domain ATG101 PF07855.12 EAQ84363.1 - 0.0044 17.0 0.6 0.022 14.7 0.6 2.1 1 1 0 1 1 1 1 Autophagy-related protein 101 CAP_N PF01213.19 EAQ84363.1 - 0.005 16.4 0.3 0.0068 15.9 0.3 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal DUF2660 PF10859.8 EAQ84363.1 - 0.014 15.8 0.4 0.035 14.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2660) bacHORMA_2 PF18173.1 EAQ84363.1 - 0.11 12.4 0.1 0.26 11.1 0.1 1.5 1 1 0 1 1 1 0 Bacterial HORMA domain 2 UCH PF00443.29 EAQ84364.1 - 6.2e-35 120.9 0.0 8.9e-35 120.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 EAQ84364.1 - 5.8e-25 87.4 10.6 2.1e-20 72.8 2.2 3.0 2 0 0 2 2 2 2 Zn-finger in ubiquitin-hydrolases and other protein zf-UBP_var PF17807.1 EAQ84364.1 - 5.8e-24 83.6 3.2 7.4e-23 80.1 0.3 2.5 2 0 0 2 2 2 1 Variant UBP zinc finger UBA PF00627.31 EAQ84364.1 - 1.4e-15 56.9 0.0 1e-08 34.9 0.0 2.5 2 0 0 2 2 2 2 UBA/TS-N domain UCH_1 PF13423.6 EAQ84364.1 - 3e-15 56.7 2.4 8.8e-06 25.5 0.5 3.7 3 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase Aa_trans PF01490.18 EAQ84366.1 - 1.2e-38 132.9 17.8 8.8e-22 77.4 9.1 2.1 1 1 1 2 2 2 2 Transmembrane amino acid transporter protein Abhydrolase_1 PF00561.20 EAQ84367.1 - 0.0003 20.5 0.0 0.00044 20.0 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EAQ84367.1 - 0.022 14.0 0.0 0.044 13.1 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EAQ84367.1 - 0.11 13.1 0.0 0.19 12.3 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family ORC6 PF05460.13 EAQ84368.1 - 1.6 8.0 11.9 2.6 7.2 11.9 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) NifU_N PF01592.16 EAQ84369.1 - 4.5e-49 165.9 0.0 6.5e-49 165.3 0.0 1.2 1 0 0 1 1 1 1 NifU-like N terminal domain Acetyltransf_1 PF00583.25 EAQ84369.1 - 3.5e-05 24.0 0.0 7.9e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family HTH_psq PF05225.16 EAQ84370.1 - 1.2e-10 41.0 0.0 3.4e-10 39.5 0.0 1.9 1 0 0 1 1 1 1 helix-turn-helix, Psq domain DDE_1 PF03184.19 EAQ84370.1 - 4.1e-09 36.3 0.0 1.1e-08 35.0 0.0 1.7 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 EAQ84370.1 - 8.9e-08 32.1 0.0 2.3e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Macoilin PF09726.9 EAQ84370.1 - 0.022 13.4 2.8 0.03 12.9 2.8 1.1 1 0 0 1 1 1 0 Macoilin family SpoIIID PF12116.8 EAQ84370.1 - 0.025 14.7 0.0 0.08 13.0 0.0 1.8 1 0 0 1 1 1 0 Stage III sporulation protein D DUF3584 PF12128.8 EAQ84370.1 - 0.056 11.0 15.3 0.078 10.5 15.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) HTH_23 PF13384.6 EAQ84370.1 - 0.095 12.5 0.2 0.44 10.4 0.0 2.2 2 0 0 2 2 2 0 Homeodomain-like domain DUF1664 PF07889.12 EAQ84370.1 - 0.1 12.6 4.9 2.4 8.2 4.3 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) Sec8_exocyst PF04048.14 EAQ84370.1 - 0.43 10.4 4.2 0.27 11.1 0.6 2.3 1 1 2 3 3 3 0 Sec8 exocyst complex component specific domain DUF87 PF01935.17 EAQ84370.1 - 0.66 10.0 2.3 1.2 9.1 2.3 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain DUF4407 PF14362.6 EAQ84370.1 - 1.2 8.5 20.7 0.26 10.6 10.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) FliJ PF02050.16 EAQ84370.1 - 1.4 9.2 17.3 3.7 7.8 0.3 3.0 1 1 2 3 3 3 0 Flagellar FliJ protein AAA_13 PF13166.6 EAQ84370.1 - 1.4 7.4 9.4 2.1 6.9 9.4 1.1 1 0 0 1 1 1 0 AAA domain Baculo_PEP_C PF04513.12 EAQ84370.1 - 2.1 8.4 7.6 4.4 7.3 3.5 2.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Prominin PF05478.11 EAQ84370.1 - 2.3 6.0 4.5 3.8 5.4 4.5 1.2 1 0 0 1 1 1 0 Prominin T3SSipB PF16535.5 EAQ84370.1 - 2.4 8.6 26.0 1.3 9.5 9.9 2.7 1 1 2 3 3 2 0 Type III cell invasion protein SipB Laminin_II PF06009.12 EAQ84370.1 - 3.1 7.8 12.1 0.25 11.4 2.0 2.9 1 1 2 3 3 3 0 Laminin Domain II Filament PF00038.21 EAQ84370.1 - 3.2 7.2 12.6 11 5.5 12.6 1.8 1 1 0 1 1 1 0 Intermediate filament protein She9_MDM33 PF05546.11 EAQ84370.1 - 3.3 7.5 8.7 14 5.4 0.2 2.3 1 1 1 2 2 2 0 She9 / Mdm33 family COG2 PF06148.11 EAQ84370.1 - 4.2 7.5 6.1 17 5.5 0.1 2.8 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Syntaxin_2 PF14523.6 EAQ84370.1 - 5.7 7.4 7.3 13 6.2 6.4 2.0 1 1 1 2 2 2 0 Syntaxin-like protein DUF2937 PF11157.8 EAQ84370.1 - 8.6 6.0 12.9 6.5 6.4 7.2 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2937) NACHT PF05729.12 EAQ84371.1 - 7.9e-05 22.6 0.0 0.00015 21.8 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 EAQ84371.1 - 0.00087 19.6 0.0 0.0021 18.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain Ank_2 PF12796.7 EAQ84371.1 - 0.0031 18.0 0.3 0.021 15.4 0.1 2.2 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAQ84371.1 - 0.0053 17.3 0.0 0.23 12.1 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) AAA_16 PF13191.6 EAQ84371.1 - 0.025 15.0 0.0 0.089 13.2 0.0 2.0 1 1 0 1 1 1 0 AAA ATPase domain NB-ARC PF00931.22 EAQ84371.1 - 0.043 13.0 0.0 0.097 11.8 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.22 EAQ84371.1 - 0.048 14.1 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 RNA helicase DUF2075 PF09848.9 EAQ84371.1 - 0.08 12.2 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA PF00004.29 EAQ84371.1 - 0.11 12.9 0.0 0.32 11.4 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 EAQ84371.1 - 0.16 12.5 0.0 0.4 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain Helo_like_N PF17111.5 EAQ84372.1 - 3.4e-63 212.8 14.6 5.9e-61 205.5 4.5 2.7 2 1 0 2 2 2 2 Fungal N-terminal domain of STAND proteins SLATT_5 PF18160.1 EAQ84372.1 - 0.0061 15.9 0.2 0.015 14.6 0.2 1.7 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain family 5 zf-RING_9 PF13901.6 EAQ84372.1 - 0.0096 15.9 8.7 0.55 10.2 2.2 2.3 1 1 1 2 2 2 2 Putative zinc-RING and/or ribbon Mei5 PF10376.9 EAQ84372.1 - 0.059 13.2 4.8 0.11 12.4 4.8 1.5 1 0 0 1 1 1 0 Double-strand recombination repair protein KxDL PF10241.9 EAQ84372.1 - 0.11 12.8 9.8 2.6 8.4 4.2 3.1 3 0 0 3 3 3 0 Uncharacterized conserved protein DUF1993 PF09351.10 EAQ84372.1 - 0.18 12.0 10.4 4.9 7.3 0.1 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF1993) V-SNARE PF05008.15 EAQ84372.1 - 0.21 12.0 10.0 1.3 9.4 1.0 3.3 3 0 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus Med10 PF09748.9 EAQ84372.1 - 0.3 11.0 3.2 2.1 8.3 0.1 2.8 2 1 0 2 2 2 0 Transcription factor subunit Med10 of Mediator complex Toxin_2 PF00451.19 EAQ84372.1 - 0.86 10.0 6.1 3.8 7.9 0.2 2.9 3 0 0 3 3 3 0 Scorpion short toxin, BmKK2 DMPK_coil PF08826.10 EAQ84372.1 - 2.3 8.4 12.1 2.7 8.2 4.6 3.2 3 0 0 3 3 3 0 DMPK coiled coil domain like Glyco_hydro2_C5 PF18565.1 EAQ84373.1 - 9.4e-35 118.6 0.4 2e-34 117.5 0.4 1.6 1 0 0 1 1 1 1 Glycoside hydrolase family 2 C-terminal domain 5 Glyco_hydro_2_C PF02836.17 EAQ84373.1 - 1e-27 97.1 0.0 1.7e-27 96.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain DUF4982 PF16355.5 EAQ84373.1 - 2.3e-23 81.9 0.3 2.3e-23 81.9 0.3 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4982) Glyco_hydro_2 PF00703.21 EAQ84373.1 - 3.4e-17 63.1 0.3 8.6e-17 61.8 0.1 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.18 EAQ84373.1 - 5.8e-17 62.1 0.1 7.7e-16 58.5 0.0 2.7 3 0 0 3 3 3 1 Glycosyl hydrolases family 2, sugar binding domain BetaGal_dom4_5 PF13364.6 EAQ84373.1 - 0.00044 20.8 0.0 0.0041 17.7 0.0 2.5 2 0 0 2 2 2 1 Beta-galactosidase jelly roll domain fn3_5 PF06280.12 EAQ84373.1 - 0.013 16.1 1.2 0.026 15.2 0.2 1.9 2 0 0 2 2 2 0 Fn3-like domain Invasin_D3 PF09134.10 EAQ84373.1 - 0.016 15.5 1.5 0.016 15.5 1.5 3.8 4 0 0 4 4 4 0 Invasin, domain 3 PBP5_C PF07943.13 EAQ84373.1 - 0.097 12.9 0.1 0.35 11.1 0.0 1.9 2 0 0 2 2 2 0 Penicillin-binding protein 5, C-terminal domain APH PF01636.23 EAQ84374.1 - 2.8e-15 56.9 0.1 4.3e-15 56.3 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EAQ84374.1 - 5e-05 23.0 0.0 9.1e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase RT_RNaseH PF17917.1 EAQ84379.1 - 2.5e-16 59.9 0.0 2.4e-15 56.7 0.0 2.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 EAQ84379.1 - 1.7e-13 50.7 0.0 2.9e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 EAQ84379.1 - 5.1e-12 45.7 0.0 9.9e-11 41.6 0.0 2.5 1 1 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Chromo PF00385.24 EAQ84379.1 - 1.7e-10 40.6 5.2 3.8e-10 39.5 5.2 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 EAQ84379.1 - 7.1e-09 35.9 0.0 2.2e-08 34.3 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 EAQ84379.1 - 0.0013 18.8 0.1 0.0063 16.6 0.1 2.2 2 0 0 2 2 2 1 Integrase zinc binding domain AT_hook PF02178.19 EAQ84379.1 - 1.3 9.1 6.7 7 6.9 6.7 2.4 1 0 0 1 1 1 0 AT hook motif RVT_1 PF00078.27 EAQ84380.1 - 5.1e-45 153.7 0.0 8.7e-45 152.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_1 PF03184.19 EAQ84380.1 - 1.1e-26 93.5 0.0 3e-26 92.1 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease Exo_endo_phos_2 PF14529.6 EAQ84380.1 - 2.2e-11 43.6 0.0 4.6e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 EAQ84380.1 - 0.00041 20.0 0.4 0.0011 18.6 0.4 1.7 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family HTH_psq PF05225.16 EAQ84380.1 - 0.012 15.3 0.0 0.033 13.9 0.0 1.8 1 0 0 1 1 1 0 helix-turn-helix, Psq domain DDE_3 PF13358.6 EAQ84380.1 - 0.032 14.0 0.0 0.11 12.2 0.0 1.9 2 0 0 2 2 2 0 DDE superfamily endonuclease Zw10 PF06248.13 EAQ84380.1 - 0.21 10.1 0.1 0.32 9.5 0.1 1.1 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 RecC_C PF17946.1 EAQ84380.1 - 0.39 10.5 6.0 2.1 8.1 0.4 2.5 2 0 0 2 2 2 0 RecC C-terminal domain Peptidase_S8 PF00082.22 EAQ84381.1 - 2.8e-25 89.2 6.8 4.1e-25 88.7 6.8 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EAQ84381.1 - 2.8e-09 37.5 0.1 7.9e-09 36.1 0.1 1.7 1 1 0 1 1 1 1 Peptidase inhibitor I9 Glyco_hydro_16 PF00722.21 EAQ84383.1 - 2.4e-16 59.7 0.0 3.6e-16 59.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.15 EAQ84383.1 - 1.6e-06 26.8 0.3 0.0021 16.6 0.0 2.1 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) Polysacc_lyase PF14099.6 EAQ84383.1 - 0.0093 15.8 3.1 1.2 8.9 0.6 2.2 2 0 0 2 2 2 2 Polysaccharide lyase DUF2401 PF10287.9 EAQ84383.1 - 0.13 11.8 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Putative TOS1-like glycosyl hydrolase (DUF2401) Ank_2 PF12796.7 EAQ84384.1 - 3.9e-91 299.8 6.1 8.8e-15 55.1 0.0 8.1 2 2 6 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAQ84384.1 - 6.2e-73 240.3 27.6 6.8e-10 39.3 0.0 10.3 5 3 7 12 12 12 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAQ84384.1 - 1.3e-61 197.2 13.2 0.0001 22.4 0.0 15.3 15 0 0 15 15 15 14 Ankyrin repeat Ank PF00023.30 EAQ84384.1 - 3.7e-60 197.9 33.2 9.1e-07 29.1 0.0 15.2 15 0 0 15 15 15 13 Ankyrin repeat Ank_5 PF13857.6 EAQ84384.1 - 2.7e-56 186.9 22.5 8.1e-07 29.2 0.1 13.7 3 3 12 15 15 15 12 Ankyrin repeats (many copies) Clr5 PF14420.6 EAQ84384.1 - 2.2e-11 43.8 2.6 4e-11 43.0 2.6 1.5 1 0 0 1 1 1 1 Clr5 domain VWA_3_C PF18571.1 EAQ84384.1 - 4.2 7.3 6.4 68 3.4 0.0 5.2 6 0 0 6 6 6 0 von Willebrand factor type A C-terminal domain PAPA-1 PF04795.12 EAQ84385.1 - 0.091 13.6 0.5 0.12 13.2 0.5 1.2 1 0 0 1 1 1 0 PAPA-1-like conserved region GMC_oxred_N PF00732.19 EAQ84387.1 - 5.1e-37 127.8 0.0 6.8e-37 127.4 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EAQ84387.1 - 5.9e-22 78.7 0.0 1.3e-21 77.7 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase TFIIA PF03153.13 EAQ84390.1 - 2.5 8.0 12.4 3.2 7.6 12.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TRAPP PF04051.16 EAQ84391.1 - 4.6e-35 120.5 0.0 5.4e-35 120.3 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component WD40 PF00400.32 EAQ84392.1 - 1e-37 127.4 6.0 1.3e-07 32.2 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAQ84392.1 - 5.2e-14 52.3 0.1 0.0014 18.8 0.0 4.9 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EAQ84392.1 - 0.056 12.8 0.0 3.4 6.9 0.0 2.7 1 1 1 2 2 2 0 WD40-like domain Ge1_WD40 PF16529.5 EAQ84392.1 - 0.13 11.2 0.0 2.3 7.1 0.0 2.5 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein SARAF PF06682.12 EAQ84393.1 - 0.69 9.5 7.4 1.8 8.1 0.0 2.3 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis zf-CCHC PF00098.23 EAQ84394.1 - 6.8e-44 146.1 60.1 2e-07 30.7 0.9 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.6 EAQ84394.1 - 3e-10 39.7 43.3 0.013 15.2 1.1 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_3 PF13917.6 EAQ84394.1 - 0.00022 21.1 41.9 0.42 10.6 0.4 7.0 4 2 2 6 6 6 3 Zinc knuckle zf-CCHC_5 PF14787.6 EAQ84394.1 - 0.0019 17.9 45.2 0.0067 16.1 1.0 6.9 4 2 3 7 7 7 5 GAG-polyprotein viral zinc-finger zf-CCHC_6 PF15288.6 EAQ84394.1 - 0.11 12.3 0.6 0.11 12.3 0.6 7.2 5 2 2 7 7 7 0 Zinc knuckle Glyco_hydro_125 PF06824.11 EAQ84395.1 - 2.9e-137 458.0 0.0 9.1e-110 367.4 0.0 2.0 1 1 1 2 2 2 2 Metal-independent alpha-mannosidase (GH125) Hydrolase_6 PF13344.6 EAQ84396.1 - 2.3e-22 79.0 0.0 9.4e-22 77.0 0.0 2.0 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EAQ84396.1 - 2.6e-13 49.8 0.0 8.5e-13 48.2 0.0 2.0 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 EAQ84396.1 - 0.0098 16.2 0.0 2.9 8.1 0.0 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase LAL_C2 PF18603.1 EAQ84396.1 - 0.12 12.6 0.0 0.27 11.4 0.0 1.6 1 0 0 1 1 1 0 L-amino acid ligase C-terminal domain 2 COX6C PF02937.15 EAQ84398.1 - 0.00028 20.9 0.0 0.00032 20.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIc tRNA-synt_1 PF00133.22 EAQ84400.1 - 3.2e-109 365.9 0.0 9.6e-48 162.8 0.0 3.1 2 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EAQ84400.1 - 3.8e-17 62.7 0.0 7.4e-17 61.7 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 EAQ84400.1 - 4.3e-06 25.7 0.0 0.002 17.0 0.0 2.6 2 1 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 EAQ84400.1 - 0.0035 16.7 0.0 0.042 13.2 0.0 2.2 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain adh_short_C2 PF13561.6 EAQ84402.1 - 2.3e-58 197.5 1.9 2.7e-58 197.3 1.9 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EAQ84402.1 - 3.1e-48 163.9 0.1 3.9e-48 163.5 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EAQ84402.1 - 5.2e-14 52.6 0.2 7.5e-14 52.0 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EAQ84402.1 - 0.0022 17.5 0.1 0.084 12.3 0.1 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Abhydrolase_6 PF12697.7 EAQ84403.1 - 1.8e-09 38.5 0.0 2.6e-09 38.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EAQ84403.1 - 1.8e-05 24.1 0.0 0.00013 21.4 0.0 2.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EAQ84403.1 - 0.0022 17.7 0.1 0.011 15.4 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold CFEM PF05730.11 EAQ84404.1 - 6.2e-14 51.8 6.8 1.1e-13 51.0 6.8 1.4 1 0 0 1 1 1 1 CFEM domain MLANA PF14991.6 EAQ84404.1 - 0.017 15.4 0.0 0.046 14.0 0.0 1.8 1 0 0 1 1 1 0 Protein melan-A EphA2_TM PF14575.6 EAQ84404.1 - 0.11 13.5 0.0 0.23 12.3 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain SOG2 PF10428.9 EAQ84404.1 - 0.24 10.6 13.2 0.31 10.2 13.2 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Ndc1_Nup PF09531.10 EAQ84404.1 - 5.1 5.7 7.7 6.2 5.4 7.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup NAM-associated PF14303.6 EAQ84404.1 - 5.2 7.8 9.6 26 5.5 0.0 2.3 1 1 1 2 2 2 0 No apical meristem-associated C-terminal domain MAP65_ASE1 PF03999.12 EAQ84404.1 - 10 4.7 8.2 12 4.5 8.2 1.0 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Ribosomal_L22 PF00237.19 EAQ84405.1 - 1.1e-21 77.0 0.2 3.2e-21 75.5 0.2 1.8 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e SKG6 PF08693.10 EAQ84406.1 - 0.011 15.1 0.2 0.021 14.2 0.2 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF4448 PF14610.6 EAQ84406.1 - 0.063 13.0 0.0 0.094 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DUF3112 PF11309.8 EAQ84407.1 - 8.3e-11 41.7 10.9 2.3e-07 30.5 0.0 2.8 3 0 0 3 3 3 2 Protein of unknown function (DUF3112) WD40 PF00400.32 EAQ84409.1 - 2.8e-44 148.2 23.3 2.7e-08 34.3 0.2 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAQ84409.1 - 8.6e-09 35.6 0.8 0.12 12.7 0.0 4.6 2 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EAQ84409.1 - 2.9e-05 22.9 6.1 0.044 12.4 0.1 4.1 1 1 3 5 5 5 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EAQ84409.1 - 0.0039 16.2 0.0 8.4 5.3 0.0 3.9 2 2 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 EAQ84409.1 - 0.018 15.0 0.5 22 5.1 0.0 4.4 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat WD40_like PF17005.5 EAQ84409.1 - 0.019 14.3 0.0 0.53 9.6 0.0 2.3 2 1 0 2 2 2 0 WD40-like domain Bromo_TP PF07524.13 EAQ84410.1 - 1.6e-16 60.0 0.0 3e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated TAF8_C PF10406.9 EAQ84410.1 - 6.7e-11 42.6 0.6 8.9e-06 26.2 0.1 2.6 2 0 0 2 2 2 2 Transcription factor TFIID complex subunit 8 C-term LRR_8 PF13855.6 EAQ84411.1 - 2e-09 37.1 2.6 4.3e-05 23.2 2.7 2.4 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 EAQ84411.1 - 1.8e-07 31.4 3.7 0.018 15.4 1.0 3.1 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) Ribosomal_60s PF00428.19 EAQ84411.1 - 0.029 14.9 1.8 0.053 14.1 1.8 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein Pkinase_Tyr PF07714.17 EAQ84411.1 - 0.051 12.8 0.0 0.83 8.9 0.0 2.2 2 0 0 2 2 2 0 Protein tyrosine kinase Kdo PF06293.14 EAQ84411.1 - 0.074 12.4 0.1 0.13 11.6 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family LRR_9 PF14580.6 EAQ84411.1 - 0.18 11.3 0.1 0.39 10.2 0.1 1.5 1 1 0 1 1 1 0 Leucine-rich repeat LRR_1 PF00560.33 EAQ84411.1 - 6.5 7.7 9.8 54 4.9 1.0 4.3 4 1 0 4 4 4 0 Leucine Rich Repeat 2OG-FeII_Oxy_2 PF13532.6 EAQ84412.1 - 2.1e-28 99.9 0.1 4.3e-28 98.8 0.1 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Isochorismatase PF00857.20 EAQ84412.1 - 2e-27 96.5 0.0 8.2e-27 94.5 0.0 2.0 1 1 0 1 1 1 1 Isochorismatase family GST_C_2 PF13410.6 EAQ84412.1 - 0.0014 18.6 0.1 0.0031 17.5 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain SHMT PF00464.19 EAQ84413.1 - 3.5e-109 365.1 0.0 4.2e-109 364.8 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_5 PF00266.19 EAQ84413.1 - 0.022 13.7 0.0 0.028 13.4 0.0 1.1 1 0 0 1 1 1 0 Aminotransferase class-V Beta_elim_lyase PF01212.21 EAQ84413.1 - 0.084 12.1 0.0 0.12 11.6 0.0 1.4 1 1 0 1 1 1 0 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 EAQ84413.1 - 0.086 12.1 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 EAQ84413.1 - 0.14 11.3 0.0 0.2 10.8 0.0 1.4 1 1 0 1 1 1 0 Aminotransferase class I and II Ribosomal_L19e PF01280.20 EAQ84414.1 - 9.8e-62 207.3 5.5 9.8e-62 207.3 5.5 1.8 1 1 1 2 2 2 1 Ribosomal protein L19e Gcn1_N PF12074.8 EAQ84415.1 - 5.6e-130 433.8 3.7 1.9e-128 428.8 0.4 4.3 3 0 0 3 3 3 1 Generalcontrol nonderepressible 1 (Gcn1) N-terminal HEAT PF02985.22 EAQ84415.1 - 1.2e-35 118.5 39.3 0.02 15.1 0.1 24.3 28 0 0 28 28 25 8 HEAT repeat HEAT_EZ PF13513.6 EAQ84415.1 - 2.8e-27 94.7 59.2 1.2e-07 32.0 0.0 20.4 18 3 8 26 26 20 7 HEAT-like repeat HEAT_2 PF13646.6 EAQ84415.1 - 4.7e-27 94.2 51.5 1.3e-05 25.5 0.0 16.2 12 4 7 19 19 18 11 HEAT repeats Cnd1 PF12717.7 EAQ84415.1 - 4.3e-16 59.4 9.8 0.66 10.0 0.3 12.2 10 2 5 15 15 13 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 EAQ84415.1 - 3.2e-14 53.3 0.0 1.8 9.2 0.0 9.9 8 2 2 10 10 8 2 Vacuolar 14 Fab1-binding region ParcG PF10274.9 EAQ84415.1 - 3.9e-13 49.9 0.6 0.00011 22.4 0.0 5.6 4 1 1 5 5 5 3 Parkin co-regulated protein CLASP_N PF12348.8 EAQ84415.1 - 1.8e-11 44.0 0.1 0.096 12.2 0.0 6.9 5 2 2 8 8 8 4 CLASP N terminal UME PF08064.13 EAQ84415.1 - 2.3e-10 40.3 0.5 3 7.8 0.0 8.6 7 2 1 8 8 8 2 UME (NUC010) domain Adaptin_N PF01602.20 EAQ84415.1 - 3.7e-09 35.7 10.5 0.0087 14.7 1.1 7.9 5 4 3 8 8 8 2 Adaptin N terminal region MMS19_C PF12460.8 EAQ84415.1 - 2.3e-06 27.0 13.6 0.0042 16.3 0.2 6.3 5 1 1 6 6 6 2 RNAPII transcription regulator C-terminal TIP120 PF08623.10 EAQ84415.1 - 1.4e-05 24.9 0.2 0.067 13.0 0.0 5.8 6 1 1 7 7 7 1 TATA-binding protein interacting (TIP20) Tti2 PF10521.9 EAQ84415.1 - 0.00011 21.9 1.1 0.16 11.5 0.0 5.5 6 0 0 6 6 6 1 Tti2 family DRIM PF07539.12 EAQ84415.1 - 0.00025 19.5 6.4 0.019 13.3 0.2 4.0 4 0 0 4 4 4 2 Down-regulated in metastasis TFCD_C PF12612.8 EAQ84415.1 - 0.00042 20.2 1.2 0.0049 16.7 0.0 3.5 3 0 0 3 3 3 1 Tubulin folding cofactor D C terminal DUF937 PF06078.11 EAQ84415.1 - 0.0024 18.5 5.8 10 6.7 0.0 6.9 6 2 1 7 7 7 0 Bacterial protein of unknown function (DUF937) IFRD PF05004.13 EAQ84415.1 - 0.0052 15.9 14.9 0.0069 15.5 2.3 6.1 7 0 0 7 7 7 1 Interferon-related developmental regulator (IFRD) RasGEF_N_2 PF14663.6 EAQ84415.1 - 0.0056 17.1 0.5 2.2 8.7 0.0 4.8 5 0 0 5 5 4 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain Pes-10 PF07149.11 EAQ84415.1 - 0.03 13.4 0.0 0.081 12.0 0.0 1.6 1 0 0 1 1 1 0 Pes-10 Ipi1_N PF12333.8 EAQ84415.1 - 0.066 13.8 0.2 1.2 9.7 0.1 3.3 3 0 0 3 3 2 0 Rix1 complex component involved in 60S ribosome maturation HEAT_PBS PF03130.16 EAQ84415.1 - 0.11 13.2 32.3 0.8 10.6 0.2 11.4 11 0 0 11 11 9 0 PBS lyase HEAT-like repeat FANCI_S2 PF14676.6 EAQ84415.1 - 0.11 12.8 1.1 2.9 8.2 0.1 3.8 3 2 1 4 4 4 0 FANCI solenoid 2 RIX1 PF08167.12 EAQ84415.1 - 0.25 11.1 9.3 0.11 12.2 0.4 5.0 5 0 0 5 5 5 0 rRNA processing/ribosome biogenesis Dopey_N PF04118.14 EAQ84415.1 - 0.34 10.0 1.9 45 3.0 0.0 4.6 3 1 1 5 5 5 0 Dopey, N-terminal U3snoRNP10 PF12397.8 EAQ84415.1 - 7.2 7.0 16.4 73 3.8 0.2 7.0 7 1 1 8 8 6 0 U3 small nucleolar RNA-associated protein 10 Arm PF00514.23 EAQ84415.1 - 7.4 6.8 18.3 53 4.1 0.0 9.4 10 1 0 10 10 8 0 Armadillo/beta-catenin-like repeat HA2 PF04408.23 EAQ84416.1 - 1.5e-14 54.2 0.8 3.7e-14 52.9 0.0 2.1 2 0 0 2 2 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EAQ84416.1 - 6.6e-14 52.2 0.0 1.8e-13 50.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EAQ84416.1 - 1.7e-10 40.9 0.1 3.5e-10 39.9 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.16 EAQ84416.1 - 1.2e-08 35.2 0.0 2.8e-08 34.0 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.6 EAQ84416.1 - 7.4e-08 32.8 0.7 2.4e-07 31.1 0.2 2.1 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EAQ84416.1 - 0.0047 17.3 0.1 0.031 14.6 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_23 PF13476.6 EAQ84416.1 - 0.032 14.7 5.3 0.055 14.0 0.0 3.3 3 0 0 3 3 3 0 AAA domain AAA_29 PF13555.6 EAQ84416.1 - 0.046 13.5 0.0 0.15 11.8 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain Rad17 PF03215.15 EAQ84416.1 - 0.048 13.6 0.2 0.14 12.1 0.0 1.7 2 0 0 2 2 2 0 Rad17 P-loop domain ABC_tran PF00005.27 EAQ84416.1 - 0.064 13.8 0.0 0.22 12.0 0.0 1.9 1 0 0 1 1 1 0 ABC transporter Sigma54_activat PF00158.26 EAQ84416.1 - 0.087 12.5 0.1 1.3 8.7 0.0 2.7 3 0 0 3 3 3 0 Sigma-54 interaction domain ATPase PF06745.13 EAQ84416.1 - 0.14 11.4 0.0 0.3 10.4 0.0 1.5 1 0 0 1 1 1 0 KaiC DUF1658 PF07871.11 EAQ84417.1 - 4.5 7.4 6.9 19 5.4 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1658) Patatin PF01734.22 EAQ84418.1 - 4.1e-24 85.9 0.0 9.8e-24 84.7 0.0 1.7 1 0 0 1 1 1 1 Patatin-like phospholipase NB-ARC PF00931.22 EAQ84418.1 - 1.3e-07 31.1 0.0 6.3e-07 28.8 0.0 2.1 1 1 0 1 1 1 1 NB-ARC domain TPR_12 PF13424.6 EAQ84418.1 - 4.5e-05 23.7 2.5 0.084 13.2 0.0 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat AAA_22 PF13401.6 EAQ84418.1 - 0.0002 21.6 0.0 0.0011 19.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EAQ84418.1 - 0.0028 18.0 0.0 0.013 15.9 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain CbiA PF01656.23 EAQ84418.1 - 0.015 15.4 0.0 0.052 13.6 0.0 2.0 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain NACHT PF05729.12 EAQ84418.1 - 0.017 15.1 0.2 0.049 13.6 0.2 1.8 1 1 0 1 1 1 0 NACHT domain TPR_10 PF13374.6 EAQ84418.1 - 0.021 14.7 10.3 0.34 10.9 0.1 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat IstB_IS21 PF01695.17 EAQ84418.1 - 0.079 12.7 0.0 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein Zeta_toxin PF06414.12 EAQ84418.1 - 0.11 11.7 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin TPR_7 PF13176.6 EAQ84418.1 - 0.16 12.0 1.6 5.6 7.2 0.0 3.9 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 EAQ84418.1 - 4.9 7.9 6.7 1.2 9.8 0.6 3.1 3 0 0 3 3 2 0 Tetratricopeptide repeat Adeno_PVIII PF01310.18 EAQ84419.1 - 0.08 12.5 0.0 0.082 12.5 0.0 1.1 1 0 0 1 1 1 0 Adenovirus hexon associated protein, protein VIII Abhydrolase_3 PF07859.13 EAQ84420.1 - 6.3e-32 111.1 0.2 8.1e-32 110.8 0.2 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 EAQ84421.1 - 1.7e-22 79.5 0.0 4.2e-22 78.2 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.20 EAQ84421.1 - 3.1e-09 36.9 0.0 1.3e-05 25.0 0.0 2.9 2 1 0 2 2 2 2 alpha/beta hydrolase fold Fungal_trans PF04082.18 EAQ84422.1 - 9.5e-24 83.8 0.1 1.6e-23 83.1 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EAQ84422.1 - 5e-08 32.9 10.5 8.1e-08 32.3 10.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PBP1_TM PF14812.6 EAQ84422.1 - 0.039 14.3 0.7 0.12 12.8 0.7 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal MR_MLE_C PF13378.6 EAQ84423.1 - 4.3e-43 147.4 0.0 5.9e-43 147.0 0.0 1.1 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 EAQ84423.1 - 2e-10 40.9 0.0 3.4e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Glyco_hydro_42 PF02449.15 EAQ84423.1 - 0.17 11.2 0.0 0.49 9.7 0.0 1.6 2 0 0 2 2 2 0 Beta-galactosidase adh_short_C2 PF13561.6 EAQ84424.1 - 2.9e-51 174.3 0.0 4.2e-51 173.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EAQ84424.1 - 1.5e-36 125.7 0.1 2.5e-36 125.0 0.1 1.3 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EAQ84424.1 - 1.3e-06 28.4 0.2 2.3e-06 27.6 0.2 1.4 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 EAQ84424.1 - 0.092 12.1 0.1 0.52 9.6 0.0 2.0 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DIOX_N PF14226.6 EAQ84425.1 - 3.5e-16 60.0 0.0 6.5e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EAQ84425.1 - 1.5e-11 44.7 0.0 3e-11 43.7 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily FAD_binding_4 PF01565.23 EAQ84426.1 - 3.4e-27 94.9 1.5 3.4e-27 94.9 1.5 1.6 2 0 0 2 2 2 1 FAD binding domain NTP_transf_3 PF12804.7 EAQ84426.1 - 0.0012 19.2 1.4 1.3 9.4 0.1 2.4 2 0 0 2 2 2 2 MobA-like NTP transferase domain BBE PF08031.12 EAQ84426.1 - 0.15 12.2 0.0 0.3 11.2 0.0 1.4 1 0 0 1 1 1 0 Berberine and berberine like Cupin_2 PF07883.11 EAQ84427.1 - 2.8e-07 30.2 0.1 5.5e-07 29.2 0.1 1.4 1 0 0 1 1 1 1 Cupin domain adh_short PF00106.25 EAQ84428.1 - 1.2e-16 60.8 0.0 6.1e-13 48.7 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EAQ84428.1 - 3.9e-06 26.6 0.0 6.6e-05 22.6 0.0 2.1 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EAQ84428.1 - 0.0047 16.9 0.2 0.01 15.8 0.1 1.6 2 0 0 2 2 2 1 KR domain DUF2101 PF09874.9 EAQ84429.1 - 0.28 10.9 0.1 0.28 10.9 0.1 1.8 2 0 0 2 2 2 0 Predicted membrane protein (DUF2101) DUF5336 PF17270.2 EAQ84429.1 - 2.3 7.8 7.4 0.14 11.8 1.4 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5336) FAD_binding_4 PF01565.23 EAQ84430.1 - 1.1e-26 93.3 2.4 2e-26 92.4 2.4 1.4 1 0 0 1 1 1 1 FAD binding domain Methyltransf_11 PF08241.12 EAQ84431.1 - 2.9e-10 40.6 0.0 4.9e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAQ84431.1 - 9.6e-10 39.0 0.0 1.7e-09 38.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EAQ84431.1 - 5.7e-08 32.8 0.0 7.4e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAQ84431.1 - 3.1e-07 30.3 0.0 4.2e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EAQ84431.1 - 2.4e-05 25.0 0.0 3.7e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Hce2 PF14856.6 EAQ84432.1 - 2.6e-14 53.4 0.1 3.5e-14 52.9 0.1 1.2 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor NACHT_N PF17100.5 EAQ84433.1 - 1.4e-40 139.5 0.1 2e-40 139.0 0.1 1.2 1 0 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase NACHT PF05729.12 EAQ84433.1 - 1e-08 35.3 0.0 1.9e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EAQ84433.1 - 0.00098 19.5 0.0 0.003 17.9 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EAQ84433.1 - 0.021 15.1 0.0 0.069 13.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EAQ84433.1 - 0.03 14.5 0.0 0.072 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 EAQ84433.1 - 0.11 11.7 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) SR-25 PF10500.9 EAQ84434.1 - 4.8 6.7 21.2 7 6.2 21.2 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Tyrosinase PF00264.20 EAQ84435.1 - 3.1e-14 53.8 3.6 6.1e-13 49.6 1.1 4.4 5 1 2 7 7 7 2 Common central domain of tyrosinase GAS PF13851.6 EAQ84435.1 - 0.0027 17.1 11.9 0.0027 17.1 11.9 2.6 1 1 1 3 3 3 1 Growth-arrest specific micro-tubule binding ZapB PF06005.12 EAQ84435.1 - 0.0057 17.1 1.4 0.0057 17.1 1.4 3.9 3 1 0 3 3 2 1 Cell division protein ZapB FlxA PF14282.6 EAQ84435.1 - 0.41 10.7 12.4 0.89 9.6 4.2 3.4 2 1 0 3 3 3 0 FlxA-like protein HOOK PF05622.12 EAQ84435.1 - 0.5 8.4 33.8 4.2 5.4 31.9 1.9 1 1 1 2 2 2 0 HOOK protein Tropomyosin_1 PF12718.7 EAQ84435.1 - 0.53 10.4 30.1 0.18 12.0 25.6 2.3 1 1 1 2 2 2 0 Tropomyosin like Phage_GP20 PF06810.11 EAQ84435.1 - 1.2 8.9 11.4 1.1 9.1 2.1 2.8 1 1 2 3 3 3 0 Phage minor structural protein GP20 Lebercilin PF15619.6 EAQ84435.1 - 1.8 8.2 33.6 0.4 10.3 10.9 3.2 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DUF1664 PF07889.12 EAQ84435.1 - 2.3 8.2 8.8 0.59 10.2 1.5 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 EAQ84435.1 - 4.8 7.4 14.3 0.37 11.0 2.9 3.0 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family EzrA PF06160.12 EAQ84435.1 - 5.5 5.0 18.3 6.2 4.9 17.4 1.3 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA KASH_CCD PF14662.6 EAQ84435.1 - 6 6.7 30.9 2.8 7.7 5.9 3.2 2 1 1 3 3 3 0 Coiled-coil region of CCDC155 or KASH AAA_13 PF13166.6 EAQ84435.1 - 6.8 5.2 11.0 12 4.4 11.0 1.3 1 0 0 1 1 1 0 AAA domain Cnn_1N PF07989.11 EAQ84435.1 - 7.6 6.8 19.4 0.16 12.1 1.9 3.8 2 1 0 3 3 3 0 Centrosomin N-terminal motif 1 SHE3 PF17078.5 EAQ84435.1 - 8.8 6.0 18.9 1.2e+02 2.3 18.7 2.4 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 HET PF06985.11 EAQ84436.1 - 7.6e-32 110.7 0.0 3e-31 108.7 0.0 1.9 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Mannosyl_trans3 PF11051.8 EAQ84438.1 - 0.016 14.6 0.0 0.023 14.1 0.0 1.2 1 0 0 1 1 1 0 Mannosyltransferase putative PRCC PF10253.9 EAQ84438.1 - 0.046 14.5 1.7 0.065 14.0 1.7 1.2 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Glyco_transf_8 PF01501.20 EAQ84438.1 - 0.079 12.5 0.2 8.4 5.9 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferase family 8 DUF3530 PF12048.8 EAQ84438.1 - 0.62 9.4 2.8 0.94 8.8 2.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) SSFA2_C PF14723.6 EAQ84439.1 - 0.092 12.6 3.9 0.13 12.1 3.9 1.3 1 0 0 1 1 1 0 Sperm-specific antigen 2 C-terminus SR-25 PF10500.9 EAQ84439.1 - 5.7 6.5 14.7 7.9 6.0 14.7 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Exo_endo_phos_2 PF14529.6 EAQ84441.1 - 2.4e-17 62.9 0.0 9.2e-17 61.0 0.0 2.0 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase RVT_1 PF00078.27 EAQ84441.1 - 1.4e-05 24.7 0.1 0.011 15.3 0.0 3.1 3 0 0 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 EAQ84441.1 - 0.0023 18.0 1.7 0.0023 18.0 1.7 2.5 2 0 0 2 2 1 1 Zinc knuckle SlyX PF04102.12 EAQ84441.1 - 0.0049 17.5 5.5 0.063 13.9 5.4 2.8 1 1 1 2 2 2 1 SlyX USP8_interact PF08941.10 EAQ84441.1 - 0.078 12.8 0.1 0.17 11.7 0.1 1.6 1 0 0 1 1 1 0 USP8 interacting MLTR_LBD PF17765.1 EAQ84441.1 - 0.095 12.8 1.9 0.63 10.2 0.0 3.1 3 0 0 3 3 3 0 MmyB-like transcription regulator ligand binding domain DUF812 PF05667.11 EAQ84441.1 - 0.099 11.5 1.8 0.17 10.7 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) CorA PF01544.18 EAQ84441.1 - 0.12 11.7 1.8 0.21 10.8 1.8 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein BLOC1_2 PF10046.9 EAQ84441.1 - 0.3 11.4 0.8 0.72 10.2 0.8 1.6 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 PKcGMP_CC PF16808.5 EAQ84441.1 - 0.47 10.4 2.8 0.35 10.8 0.6 2.0 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF2968 PF11180.8 EAQ84441.1 - 1.3 8.6 6.8 3 7.4 6.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) zf-RVT PF13966.6 EAQ84441.1 - 3.8 8.3 5.2 0.62 10.8 0.1 2.4 2 0 0 2 2 1 0 zinc-binding in reverse transcriptase Hce2 PF14856.6 EAQ84442.1 - 0.0016 18.7 0.0 0.0034 17.7 0.0 1.6 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor Methyltransf_25 PF13649.6 EAQ84443.1 - 1.6e-06 28.7 0.1 9.1e-06 26.3 0.1 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EAQ84443.1 - 4.5e-05 24.1 0.0 0.00011 22.8 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAQ84443.1 - 0.00015 21.6 0.0 0.00024 20.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EAQ84443.1 - 0.00079 20.0 0.0 0.0041 17.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 EAQ84443.1 - 0.0029 17.0 0.0 0.0062 15.9 0.0 1.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 EAQ84443.1 - 0.012 15.5 0.0 0.018 14.9 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.6 EAQ84443.1 - 0.012 15.6 0.0 0.018 15.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain DREV PF05219.12 EAQ84443.1 - 0.016 14.3 0.0 0.022 13.9 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase MTS PF05175.14 EAQ84443.1 - 0.017 14.7 0.0 0.023 14.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain 3HCDH_N PF02737.18 EAQ84443.1 - 0.021 14.7 0.1 0.032 14.1 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_33 PF10017.9 EAQ84443.1 - 0.04 13.1 0.0 0.053 12.7 0.0 1.1 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent PIN_10 PF18478.1 EAQ84443.1 - 0.08 13.2 0.1 0.17 12.1 0.1 1.5 1 0 0 1 1 1 0 PIN like domain PCMT PF01135.19 EAQ84443.1 - 0.084 12.6 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DEC-1_N PF04625.13 EAQ84443.1 - 0.88 8.5 3.0 1.1 8.2 3.0 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region RRM_1 PF00076.22 EAQ84444.1 - 2.6e-44 148.9 0.1 9.8e-16 57.3 0.0 5.3 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EAQ84444.1 - 1.2e-23 82.8 0.0 1.1e-16 60.5 0.0 4.8 4 1 0 4 4 4 3 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 EAQ84444.1 - 1.2e-05 25.2 0.0 0.11 12.5 0.0 3.4 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif Lsm_interact PF05391.11 EAQ84444.1 - 0.0073 15.8 1.0 0.019 14.5 1.0 1.7 1 0 0 1 1 1 1 Lsm interaction motif RRM_3 PF08777.11 EAQ84444.1 - 0.0093 16.0 4.9 0.019 15.0 0.0 3.7 5 0 0 5 5 5 1 RNA binding motif Serglycin PF04360.12 EAQ84444.1 - 0.016 15.1 1.5 0.036 14.0 1.5 1.5 1 0 0 1 1 1 0 Serglycin RRM_7 PF16367.5 EAQ84444.1 - 0.023 14.8 0.0 12 6.1 0.0 3.6 4 0 0 4 4 4 0 RNA recognition motif RRM_Rrp7 PF17799.1 EAQ84444.1 - 0.063 13.1 0.0 50 3.6 0.0 3.3 3 0 0 3 3 3 0 Rrp7 RRM-like N-terminal domain Wound_ind PF08186.11 EAQ84444.1 - 0.24 11.9 2.6 8.9 6.8 0.0 2.7 2 0 0 2 2 2 0 Wound-inducible basic protein family F-box PF00646.33 EAQ84447.1 - 0.0063 16.4 0.2 0.014 15.2 0.2 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EAQ84447.1 - 0.038 13.9 0.1 0.088 12.7 0.1 1.7 1 0 0 1 1 1 0 F-box-like DCA16 PF15349.6 EAQ84447.1 - 0.45 10.0 2.4 13 5.2 0.1 2.3 2 0 0 2 2 2 0 DDB1- and CUL4-associated factor 16 Peroxidase_2 PF01328.17 EAQ84448.1 - 2.6e-52 178.1 0.1 3.3e-52 177.7 0.1 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 Fungal_trans_2 PF11951.8 EAQ84449.1 - 7.1e-07 28.4 0.5 1e-06 27.8 0.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain RRF PF01765.19 EAQ84449.1 - 0.013 15.5 0.2 0.021 14.8 0.2 1.2 1 0 0 1 1 1 0 Ribosome recycling factor DUF1418 PF07214.12 EAQ84449.1 - 0.3 11.0 4.2 0.16 11.8 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1418) adh_short PF00106.25 EAQ84451.1 - 4.4e-08 32.8 0.0 7.4e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EAQ84451.1 - 6.3e-08 32.7 0.1 9.7e-08 32.1 0.1 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 EAQ84451.1 - 6.1e-07 29.2 0.0 9.4e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Lipase_GDSL_2 PF13472.6 EAQ84453.1 - 1.3e-14 55.0 0.1 1.6e-14 54.7 0.1 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EAQ84453.1 - 3.9e-08 33.5 0.0 4.3e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 EAQ84453.1 - 0.066 13.3 0.2 0.087 12.9 0.2 1.4 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family OSK PF17182.4 EAQ84453.1 - 0.13 11.5 0.0 0.15 11.2 0.0 1.1 1 0 0 1 1 1 0 OSK domain CN_hydrolase PF00795.22 EAQ84454.1 - 4.2e-28 98.4 0.1 4.2e-19 68.9 0.0 2.0 1 1 1 2 2 2 2 Carbon-nitrogen hydrolase STE2 PF02116.15 EAQ84455.1 - 2e-64 217.6 20.2 2.1e-57 194.6 16.7 2.0 1 1 1 2 2 2 2 Fungal pheromone mating factor STE2 GPCR UEV PF05743.13 EAQ84457.1 - 9.3e-33 112.7 0.1 1.5e-32 112.0 0.1 1.3 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.10 EAQ84457.1 - 7.8e-22 77.0 1.0 1e-21 76.6 0.0 1.8 2 0 0 2 2 2 1 Vps23 core domain IDO PF01231.18 EAQ84458.1 - 1e-166 555.0 0.0 1.2e-166 554.8 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase TFB6 PF17110.5 EAQ84460.1 - 1.9e-54 184.0 0.0 2.6e-54 183.6 0.0 1.2 1 0 0 1 1 1 1 Subunit 11 of the general transcription factor TFIIH Glyco_hydro_7 PF00840.20 EAQ84461.1 - 4.3e-125 417.9 1.3 7.4e-124 413.8 1.3 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 7 COesterase PF00135.28 EAQ84464.1 - 1.3e-76 258.5 0.0 2.7e-76 257.5 0.0 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EAQ84464.1 - 8.4e-05 22.5 0.1 0.00084 19.3 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold MFS_1 PF07690.16 EAQ84465.1 - 1.8e-25 89.6 35.3 1.2e-22 80.3 26.6 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EAQ84465.1 - 0.0066 15.4 1.0 0.0066 15.4 1.0 1.7 2 0 0 2 2 2 1 MFS_1 like family p450 PF00067.22 EAQ84466.1 - 5e-18 65.1 0.0 4.6e-17 61.9 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 Glyco_hydro_61 PF03443.14 EAQ84467.1 - 2.2e-54 184.5 0.1 3.1e-54 184.1 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.18 EAQ84467.1 - 1.6e-12 47.2 13.2 1.6e-12 47.2 13.2 2.1 2 0 0 2 2 2 1 Fungal cellulose binding domain RVT_1 PF00078.27 EAQ84468.1 - 2.8e-11 43.3 0.0 5e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) F-box_4 PF15966.5 EAQ84468.1 - 0.0013 18.6 0.1 0.089 12.7 0.0 2.5 2 0 0 2 2 2 1 F-box F-box-like PF12937.7 EAQ84468.1 - 0.0015 18.3 0.1 0.0015 18.3 0.1 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EAQ84468.1 - 0.0072 16.2 0.1 0.02 14.8 0.1 1.8 1 0 0 1 1 1 1 F-box domain zf-RVT PF13966.6 EAQ84468.1 - 0.024 15.3 0.2 0.071 13.8 0.2 1.7 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase Ribonuc_2-5A PF06479.12 EAQ84468.1 - 0.093 12.9 0.1 0.31 11.2 0.0 1.9 2 0 0 2 2 2 0 Ribonuclease 2-5A MFS_1 PF07690.16 EAQ84469.1 - 9.8e-39 133.3 53.0 2e-38 132.2 47.7 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EAQ84469.1 - 6.1e-13 48.4 13.9 1.5e-12 47.2 13.9 1.6 1 0 0 1 1 1 1 Sugar (and other) transporter Pkinase PF00069.25 EAQ84470.1 - 0.016 14.6 0.0 0.021 14.2 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain APH PF01636.23 EAQ84470.1 - 0.044 13.7 0.1 0.074 13.0 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 EAQ84470.1 - 0.13 11.8 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Atg29_N PF18388.1 EAQ84470.1 - 0.58 10.0 8.2 0.1 12.4 1.0 2.3 2 0 0 2 2 2 0 Atg29 N-terminal domain DUF4413 PF14372.6 EAQ84471.1 - 5.3e-05 23.5 0.3 0.33 11.3 0.1 3.0 3 0 0 3 3 3 2 Domain of unknown function (DUF4413) zf-BED PF02892.15 EAQ84471.1 - 0.0015 18.5 0.4 0.0034 17.4 0.4 1.6 1 0 0 1 1 1 1 BED zinc finger DUF4174 PF13778.6 EAQ84471.1 - 0.018 15.5 0.0 0.042 14.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4174) zf-RING_10 PF16685.5 EAQ84471.1 - 0.036 14.2 0.1 0.075 13.2 0.1 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 7tm_4 PF13853.6 EAQ84471.1 - 0.058 13.1 0.0 0.09 12.5 0.0 1.2 1 0 0 1 1 1 0 Olfactory receptor Glycoprot_B_PH2 PF17417.2 EAQ84471.1 - 0.082 13.2 0.1 0.24 11.7 0.1 1.8 1 0 0 1 1 1 0 Herpesvirus Glycoprotein B PH-like domain DUF4292 PF14125.6 EAQ84472.1 - 0.091 12.4 0.2 0.17 11.5 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4292) TMEM154 PF15102.6 EAQ84473.1 - 1.5 8.7 3.9 2.4 8.1 3.9 1.4 1 0 0 1 1 1 0 TMEM154 protein family Hamartin PF04388.12 EAQ84473.1 - 2.7 6.6 7.8 2.8 6.5 7.8 1.1 1 0 0 1 1 1 0 Hamartin protein IHABP4_N PF16174.5 EAQ84473.1 - 8.3 7.0 13.4 2.4 8.7 10.6 1.5 1 1 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal NmrA PF05368.13 EAQ84475.1 - 1.8e-38 132.4 0.1 2.3e-38 132.1 0.1 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EAQ84475.1 - 1e-10 41.8 0.1 1.7e-10 41.1 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EAQ84475.1 - 2.2e-05 24.1 0.0 2.9e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EAQ84475.1 - 0.00039 19.5 0.0 0.00052 19.1 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 EAQ84475.1 - 0.024 15.1 0.1 0.071 13.6 0.1 1.8 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 EAQ84475.1 - 0.066 13.3 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DapB_N PF01113.20 EAQ84475.1 - 0.083 13.0 0.3 0.36 11.0 0.1 2.2 3 0 0 3 3 3 0 Dihydrodipicolinate reductase, N-terminus Peptidase_S28 PF05577.12 EAQ84476.1 - 4.9e-31 108.0 0.0 5.8e-25 88.0 0.0 2.1 2 0 0 2 2 2 2 Serine carboxypeptidase S28 Aminotran_5 PF00266.19 EAQ84477.1 - 1.6e-33 116.2 0.0 3.8e-22 78.8 0.0 2.0 2 0 0 2 2 2 2 Aminotransferase class-V ADH_N PF08240.12 EAQ84479.1 - 8.2e-19 67.5 0.1 2e-18 66.3 0.0 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EAQ84479.1 - 1.9e-06 27.9 0.1 1.4e-05 25.1 0.1 2.0 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.6 EAQ84479.1 - 0.00039 20.3 2.4 0.00039 20.3 2.4 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-associated Glu_dehyd_C PF16912.5 EAQ84479.1 - 0.0014 18.1 0.0 0.17 11.4 0.0 2.3 2 0 0 2 2 2 2 Glucose dehydrogenase C-terminus HI0933_like PF03486.14 EAQ84479.1 - 0.019 13.7 0.0 0.026 13.3 0.0 1.1 1 0 0 1 1 1 0 HI0933-like protein AlaDh_PNT_C PF01262.21 EAQ84479.1 - 0.2 10.9 0.0 0.34 10.2 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Sugar_tr PF00083.24 EAQ84481.1 - 4.4e-77 259.9 15.0 5.6e-77 259.5 15.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EAQ84481.1 - 1.2e-26 93.5 29.6 1.6e-26 93.1 29.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily PEMT PF04191.13 EAQ84481.1 - 0.19 12.1 2.1 0.21 12.0 0.2 2.0 2 0 0 2 2 2 0 Phospholipid methyltransferase AnmK PF03702.14 EAQ84482.1 - 2.8e-85 286.6 0.0 3.3e-85 286.4 0.0 1.0 1 0 0 1 1 1 1 Anhydro-N-acetylmuramic acid kinase Fungal_trans PF04082.18 EAQ84483.1 - 0.0011 18.1 1.1 0.0015 17.6 1.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pox_ser-thr_kin PF05445.11 EAQ84483.1 - 0.24 10.3 0.1 0.38 9.7 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase PF00069.25 EAQ84484.1 - 3.8e-08 33.0 0.0 4.4e-08 32.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ84484.1 - 1.9e-06 27.3 0.0 2.4e-06 27.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase YTH PF04146.15 EAQ84485.1 - 4.3e-23 82.1 0.0 1.4e-22 80.4 0.0 1.8 1 1 0 1 1 1 1 YT521-B-like domain Pkinase PF00069.25 EAQ84485.1 - 4.9e-15 55.6 0.0 7.1e-15 55.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Fer4_5 PF12801.7 EAQ84485.1 - 0.61 10.1 3.4 7.1 6.7 0.3 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fungal_lectin PF07938.12 EAQ84487.1 - 6e-36 124.4 6.1 7.7e-35 120.7 6.1 2.0 1 1 0 1 1 1 1 Fungal fucose-specific lectin Helo_like_N PF17111.5 EAQ84488.1 - 4.5e-09 36.0 0.6 7e-09 35.4 0.6 1.2 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins AsmA_1 PF13109.6 EAQ84488.1 - 0.093 12.2 0.2 0.19 11.2 0.2 1.4 1 1 0 1 1 1 0 AsmA-like C-terminal region DUF1996 PF09362.10 EAQ84489.1 - 6.3e-79 265.3 1.0 7.6e-79 265.0 1.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) DUF4149 PF13664.6 EAQ84490.1 - 4.9e-19 68.6 2.2 9.8e-19 67.6 2.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4149) F-box PF00646.33 EAQ84490.1 - 0.00072 19.4 0.0 0.0022 17.8 0.0 1.9 1 0 0 1 1 1 1 F-box domain CTNNBL PF08216.11 EAQ84491.1 - 8.6e-38 128.7 0.1 6.5e-37 125.9 0.0 2.3 2 0 0 2 2 2 1 Catenin-beta-like, Arm-motif containing nuclear Arm PF00514.23 EAQ84491.1 - 0.14 12.3 0.2 1.2 9.3 0.0 2.7 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat V-ATPase_G PF03179.15 EAQ84492.1 - 2.1e-24 86.0 16.0 2.3e-24 85.9 16.0 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit DUF2203 PF09969.9 EAQ84492.1 - 0.021 15.6 6.3 0.024 15.3 6.3 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) YusW PF14039.6 EAQ84492.1 - 0.095 13.2 7.9 0.088 13.3 7.0 1.4 1 1 1 2 2 2 0 YusW-like protein FdhE PF04216.12 EAQ84492.1 - 0.24 11.2 2.9 0.29 11.0 2.9 1.0 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation MAJIN PF15077.6 EAQ84492.1 - 0.53 10.0 4.4 0.58 9.9 4.4 1.0 1 0 0 1 1 1 0 Membrane-anchored junction protein CemA PF03040.14 EAQ84492.1 - 0.56 10.1 4.8 0.64 9.9 4.8 1.1 1 0 0 1 1 1 0 CemA family RRF PF01765.19 EAQ84492.1 - 0.78 9.7 12.3 0.99 9.3 12.3 1.1 1 0 0 1 1 1 0 Ribosome recycling factor DUF4407 PF14362.6 EAQ84492.1 - 1.6 8.0 7.9 1.8 7.9 7.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Ribosomal_L37 PF08561.10 EAQ84492.1 - 1.8 9.1 12.6 2.3 8.8 12.6 1.0 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L37 SMBP PF16785.5 EAQ84492.1 - 2.2 8.5 13.0 38 4.5 12.7 2.2 1 1 0 1 1 1 0 Small metal-binding protein DUF2175 PF09943.9 EAQ84492.1 - 2.7 8.3 8.9 7.2 7.0 2.0 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) AAA_11 PF13086.6 EAQ84492.1 - 4 7.1 9.7 4.3 7.0 9.7 1.0 1 0 0 1 1 1 0 AAA domain DUF883 PF05957.13 EAQ84492.1 - 8.1 7.1 11.0 29 5.4 8.6 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) RNA_pol_Rpb2_6 PF00562.28 EAQ84493.1 - 7.8e-125 417.0 0.1 1.2e-124 416.3 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_2 PF04561.14 EAQ84493.1 - 8.3e-46 156.0 0.0 3.3e-45 154.0 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_1 PF04563.15 EAQ84493.1 - 1.5e-33 116.1 0.0 4e-30 104.8 0.0 2.2 1 1 0 2 2 2 2 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 EAQ84493.1 - 1.5e-25 89.1 0.1 4.5e-25 87.6 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 EAQ84493.1 - 2.5e-24 85.6 0.0 7.8e-24 84.0 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 RNA_pol_Rpb2_4 PF04566.13 EAQ84493.1 - 8e-22 77.3 0.9 1.7e-21 76.3 0.3 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_7 PF04560.20 EAQ84493.1 - 7.2e-19 68.0 0.1 1.8e-18 66.7 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 PDCD7 PF16021.5 EAQ84493.1 - 0.094 11.8 0.2 0.16 11.1 0.2 1.2 1 0 0 1 1 1 0 Programmed cell death protein 7 Glyco_hydro_45 PF02015.16 EAQ84495.1 - 2.8e-76 256.1 13.6 4.8e-76 255.4 13.6 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 CBM_1 PF00734.18 EAQ84495.1 - 3e-09 36.7 18.8 3e-09 36.7 18.8 2.7 2 0 0 2 2 2 1 Fungal cellulose binding domain Neisseria_TspB PF05616.13 EAQ84495.1 - 0.21 10.0 6.2 0.28 9.6 6.2 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein NAD_binding_2 PF03446.15 EAQ84498.1 - 2e-08 34.5 0.0 3.2e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 EAQ84498.1 - 0.00024 21.6 0.0 0.00047 20.7 0.0 1.6 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 EAQ84498.1 - 0.015 15.4 0.0 0.022 14.8 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_Gly3P_dh_N PF01210.23 EAQ84498.1 - 0.15 12.0 0.0 0.25 11.3 0.0 1.5 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus COesterase PF00135.28 EAQ84499.1 - 3.8e-44 151.4 0.0 2.5e-33 115.7 0.0 3.2 2 1 1 3 3 3 3 Carboxylesterase family FMN_bind_2 PF04299.12 EAQ84499.1 - 0.11 12.2 0.1 0.22 11.2 0.1 1.4 1 0 0 1 1 1 0 Putative FMN-binding domain Pox_I5 PF04713.12 EAQ84500.1 - 6.4 6.9 7.9 3.6 7.7 0.6 3.1 3 1 0 3 3 3 0 Poxvirus protein I5 CorA PF01544.18 EAQ84503.1 - 2e-08 33.9 0.4 3.2e-08 33.2 0.4 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Pectate_lyase PF03211.13 EAQ84505.1 - 6.3e-86 287.1 9.8 9.1e-86 286.6 9.8 1.2 1 0 0 1 1 1 1 Pectate lyase BTB PF00651.31 EAQ84507.1 - 4.7e-06 26.8 0.0 5.6e-05 23.3 0.0 2.2 2 0 0 2 2 2 1 BTB/POZ domain zf-C2H2_4 PF13894.6 EAQ84508.1 - 0.12 13.3 5.4 14 6.8 0.1 4.0 4 0 0 4 4 4 0 C2H2-type zinc finger RVT_1 PF00078.27 EAQ84509.1 - 9.1e-38 130.0 0.0 4.7e-37 127.6 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 EAQ84509.1 - 3.7e-26 91.3 0.0 1.2e-25 89.7 0.0 2.0 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 EAQ84509.1 - 0.00011 21.8 0.2 0.00023 20.8 0.2 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-CCHC PF00098.23 EAQ84509.1 - 0.0024 17.9 1.7 0.0024 17.9 1.7 2.6 2 0 0 2 2 2 1 Zinc knuckle Trypsin_2 PF13365.6 EAQ84510.1 - 2.5e-23 83.6 0.1 5.7e-23 82.5 0.1 1.6 1 0 0 1 1 1 1 Trypsin-like peptidase domain Beta-lactamase PF00144.24 EAQ84511.1 - 4.9e-32 111.5 2.6 8.8e-32 110.6 2.6 1.3 1 0 0 1 1 1 1 Beta-lactamase DNase_NucA_NucB PF14040.6 EAQ84511.1 - 1.2e-06 28.9 0.1 2.4e-06 27.9 0.1 1.5 1 0 0 1 1 1 1 Deoxyribonuclease NucA/NucB Chorismate_bind PF00425.18 EAQ84512.1 - 9.7e-80 267.8 0.1 7.6e-77 258.4 0.0 3.4 3 1 0 3 3 3 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 EAQ84512.1 - 2.9e-23 82.7 0.0 1.7e-20 73.7 0.0 3.0 3 1 0 3 3 3 2 Anthranilate synthase component I, N terminal region Amidase PF01425.21 EAQ84513.1 - 3.2e-27 95.6 0.1 6.4e-27 94.6 0.1 1.5 1 1 0 1 1 1 1 Amidase Glyco_hydro_88 PF07470.13 EAQ84515.1 - 8.2e-82 275.0 0.1 9.4e-82 274.8 0.1 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 MFS_1 PF07690.16 EAQ84516.1 - 7.5e-21 74.4 12.8 7.5e-21 74.4 12.8 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sm_multidrug_ex PF06695.11 EAQ84516.1 - 0.029 15.0 4.7 2.2 8.9 0.4 2.9 3 0 0 3 3 3 0 Putative small multi-drug export protein Holin_BhlA PF10960.8 EAQ84516.1 - 0.076 13.0 0.0 0.22 11.5 0.0 1.7 1 0 0 1 1 1 0 BhlA holin family DUF3433 PF11915.8 EAQ84517.1 - 1.1e-19 70.6 23.1 8.4e-14 51.8 0.5 4.0 4 0 0 4 4 4 2 Protein of unknown function (DUF3433) HSP70 PF00012.20 EAQ84517.1 - 2.1e-09 36.1 0.0 2.8e-09 35.7 0.0 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EAQ84517.1 - 0.0032 16.3 0.0 0.0084 15.0 0.0 1.6 2 0 0 2 2 2 1 MreB/Mbl protein ADIP PF11559.8 EAQ84518.1 - 0.0085 16.2 2.4 0.023 14.8 2.4 1.7 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding APG6_N PF17675.1 EAQ84518.1 - 0.034 14.7 0.6 0.076 13.5 0.6 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region KxDL PF10241.9 EAQ84518.1 - 0.2 12.0 1.6 2.3 8.5 1.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein DUF3585 PF12130.8 EAQ84518.1 - 1.7 8.8 6.9 0.89 9.7 2.2 2.4 2 0 0 2 2 2 0 Bivalent Mical/EHBP Rab binding domain Mod_r PF07200.13 EAQ84518.1 - 2.4 8.3 6.9 2.4 8.3 3.8 2.2 2 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein SOGA PF11365.8 EAQ84518.1 - 5.4 8.2 9.2 0.41 11.8 2.4 2.5 3 0 0 3 3 3 0 Protein SOGA FAD_binding_4 PF01565.23 EAQ84519.1 - 1.4e-23 83.2 0.8 2.7e-23 82.3 0.8 1.5 1 0 0 1 1 1 1 FAD binding domain zf-C2H2_4 PF13894.6 EAQ84520.1 - 0.1 13.5 5.3 0.56 11.2 1.0 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger Exo_endo_phos_2 PF14529.6 EAQ84521.1 - 1.2e-20 73.5 0.2 5.5e-20 71.4 0.0 2.1 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 EAQ84521.1 - 0.0023 17.5 0.1 0.0052 16.3 0.1 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RVT_1 PF00078.27 EAQ84521.1 - 0.013 15.1 0.0 0.03 13.9 0.0 1.6 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Phage_Mu_Gam PF07352.12 EAQ84521.1 - 0.1 12.5 5.4 0.4 10.6 3.3 2.4 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein DUF1640 PF07798.11 EAQ84521.1 - 0.1 12.6 11.4 0.069 13.2 9.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) Spc7 PF08317.11 EAQ84521.1 - 0.14 11.0 6.4 0.27 10.1 6.4 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF1043 PF06295.12 EAQ84521.1 - 0.26 11.3 6.5 0.91 9.5 6.5 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) Prominin PF05478.11 EAQ84521.1 - 0.45 8.4 1.9 0.87 7.5 1.9 1.4 1 0 0 1 1 1 0 Prominin TACC_C PF05010.14 EAQ84521.1 - 0.66 9.7 11.2 2.1 8.1 7.7 2.2 2 0 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF1664 PF07889.12 EAQ84521.1 - 2.6 8.1 4.3 7.5 6.6 4.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Sec8_exocyst PF04048.14 EAQ84521.1 - 3.6 7.5 6.7 12 5.7 3.2 2.4 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain Baculo_PEP_C PF04513.12 EAQ84521.1 - 8.8 6.4 8.4 1.4 9.0 4.0 1.9 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fungal_lectin PF07938.12 EAQ84523.1 - 1.8e-07 30.9 0.0 1.3e-06 28.1 0.0 2.1 2 0 0 2 2 2 1 Fungal fucose-specific lectin FAM212 PF15342.6 EAQ84523.1 - 0.001 18.8 0.3 0.015 15.0 0.1 2.3 2 0 0 2 2 2 1 FAM212 family PIF1 PF05970.14 EAQ84524.1 - 0.0066 15.7 0.1 0.011 15.0 0.1 1.2 1 0 0 1 1 1 1 PIF1-like helicase UvrD_C_2 PF13538.6 EAQ84524.1 - 0.0071 16.2 0.0 0.018 14.8 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain ABC_tran PF00005.27 EAQ84525.1 - 3.3e-42 144.3 0.0 7.9e-20 71.8 0.0 3.3 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EAQ84525.1 - 3.1e-13 50.0 18.3 7.6e-13 48.7 8.0 2.7 2 1 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.6 EAQ84525.1 - 2.5e-12 47.2 0.1 0.0012 18.7 0.0 4.2 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EAQ84525.1 - 1.7e-10 40.7 1.6 0.0099 15.3 0.0 4.2 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EAQ84525.1 - 1.4e-07 31.1 0.7 0.0042 16.8 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 EAQ84525.1 - 2.2e-06 28.0 0.1 0.048 13.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 EAQ84525.1 - 5.4e-06 26.4 0.0 0.056 13.4 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EAQ84525.1 - 8e-06 25.9 0.0 0.16 12.1 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase cobW PF02492.19 EAQ84525.1 - 3.1e-05 23.6 0.1 0.14 11.7 0.0 2.5 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 EAQ84525.1 - 5.5e-05 23.6 0.0 0.52 10.7 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_33 PF13671.6 EAQ84525.1 - 7.3e-05 23.0 0.0 0.12 12.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 EAQ84525.1 - 0.00013 22.0 1.9 2.4 8.0 0.0 3.5 3 0 0 3 3 3 2 NACHT domain Dynamin_N PF00350.23 EAQ84525.1 - 0.00031 20.8 1.2 0.096 12.7 0.0 2.4 2 0 0 2 2 2 1 Dynamin family DUF87 PF01935.17 EAQ84525.1 - 0.00044 20.4 1.5 0.096 12.8 0.1 2.4 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_24 PF13479.6 EAQ84525.1 - 0.0012 18.6 0.0 0.082 12.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.18 EAQ84525.1 - 0.0013 18.2 0.0 0.2 10.9 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_18 PF13238.6 EAQ84525.1 - 0.0019 18.8 0.0 4.6 7.8 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_15 PF13175.6 EAQ84525.1 - 0.0023 17.7 0.0 1.3 8.6 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain RNA_helicase PF00910.22 EAQ84525.1 - 0.0034 17.8 0.0 1.4 9.3 0.0 2.9 4 0 0 4 4 2 1 RNA helicase AAA_25 PF13481.6 EAQ84525.1 - 0.0042 16.7 0.0 3.8 7.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 EAQ84525.1 - 0.0066 16.0 0.0 2.2 7.8 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_23 PF13476.6 EAQ84525.1 - 0.011 16.2 6.5 0.47 10.9 0.1 2.6 3 0 0 3 3 2 0 AAA domain T2SSE PF00437.20 EAQ84525.1 - 0.013 14.6 0.1 0.26 10.3 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_30 PF13604.6 EAQ84525.1 - 0.019 14.7 0.0 1.8 8.2 0.0 2.6 3 0 0 3 3 2 0 AAA domain NB-ARC PF00931.22 EAQ84525.1 - 0.02 14.1 0.0 2.3 7.3 0.0 2.7 3 0 0 3 3 3 0 NB-ARC domain KAP_NTPase PF07693.14 EAQ84525.1 - 0.047 12.9 0.0 5.5 6.1 0.0 2.4 2 0 0 2 2 2 0 KAP family P-loop domain ATP_bind_1 PF03029.17 EAQ84525.1 - 0.054 13.3 0.2 2 8.2 0.1 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein ATPase_2 PF01637.18 EAQ84525.1 - 0.061 13.2 0.2 3.5 7.5 0.0 2.6 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea GTP_EFTU PF00009.27 EAQ84525.1 - 0.075 12.6 0.0 1.2 8.7 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain NTPase_1 PF03266.15 EAQ84525.1 - 0.08 12.9 1.7 11 5.9 0.0 2.7 3 0 0 3 3 2 0 NTPase DUF3987 PF13148.6 EAQ84525.1 - 0.082 11.9 3.6 0.41 9.6 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3987) sCache_like PF16736.5 EAQ84525.1 - 0.13 12.3 0.1 0.26 11.4 0.1 1.4 1 0 0 1 1 1 0 Single Cache-like MobB PF03205.14 EAQ84525.1 - 0.14 12.1 0.1 3.2 7.6 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.6 EAQ84525.1 - 0.16 12.3 0.1 6.3 7.1 0.0 2.7 2 1 0 2 2 2 0 AAA domain Roc PF08477.13 EAQ84525.1 - 0.17 12.1 0.2 7.3 6.8 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AMP-binding PF00501.28 EAQ84526.1 - 0 1103.3 0.0 1.4e-72 244.6 0.0 6.2 6 0 0 6 6 6 6 AMP-binding enzyme Condensation PF00668.20 EAQ84526.1 - 0 1047.8 0.0 3.4e-43 148.0 0.0 11.4 9 3 0 9 9 9 9 Condensation domain PP-binding PF00550.25 EAQ84526.1 - 1.2e-79 262.6 0.0 2.3e-16 59.9 0.0 8.3 7 0 0 7 7 7 6 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EAQ84526.1 - 1.3e-09 38.9 0.1 0.48 11.4 0.0 5.1 4 0 0 4 4 4 3 AMP-binding enzyme C-terminal domain Transferase PF02458.15 EAQ84526.1 - 2.6e-06 26.3 0.0 4.3 5.9 0.0 5.2 5 0 0 5 5 5 3 Transferase family DUF3887 PF13026.6 EAQ84526.1 - 0.23 12.3 0.4 0.85 10.5 0.4 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3887) CorA PF01544.18 EAQ84527.1 - 2.3e-10 40.3 0.1 3.6e-10 39.6 0.1 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein AAA PF00004.29 EAQ84528.1 - 2.5e-06 28.0 0.0 8e-06 26.3 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MARVEL PF01284.23 EAQ84530.1 - 0.00021 21.3 6.4 0.00032 20.7 6.4 1.2 1 0 0 1 1 1 1 Membrane-associating domain Sterol_MT_C PF08498.10 EAQ84530.1 - 0.03 14.6 0.1 0.086 13.2 0.0 1.8 1 1 1 2 2 2 0 Sterol methyltransferase C-terminal Promethin PF16015.5 EAQ84530.1 - 2.4 8.1 13.2 11 6.0 7.9 2.1 2 0 0 2 2 2 0 Promethin CBM_1 PF00734.18 EAQ84531.1 - 2.2e-09 37.1 14.6 2.2e-09 37.1 14.6 2.2 2 0 0 2 2 2 1 Fungal cellulose binding domain Toxin_7 PF05980.12 EAQ84531.1 - 0.0078 16.4 10.7 0.015 15.6 10.7 1.5 1 0 0 1 1 1 1 Toxin 7 TPR_12 PF13424.6 EAQ84532.1 - 3.2e-10 40.2 9.2 0.00011 22.4 0.3 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 EAQ84532.1 - 4.2e-10 39.2 5.1 0.043 13.7 0.1 5.0 5 0 0 5 5 5 4 Tetratricopeptide repeat Ses_B PF17046.5 EAQ84532.1 - 0.045 13.7 0.2 0.073 13.0 0.2 1.3 1 0 0 1 1 1 0 SesB domain on fungal death-pathway protein TPR_2 PF07719.17 EAQ84532.1 - 0.063 13.4 0.2 1.3 9.3 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EAQ84532.1 - 0.092 13.0 0.3 4 7.7 0.1 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Sugar_tr PF00083.24 EAQ84533.1 - 8.6e-92 308.3 29.5 1.1e-91 308.0 29.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EAQ84533.1 - 1.1e-26 93.6 25.3 1.1e-26 93.6 25.3 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Fun_ATP-synt_8 PF05933.13 EAQ84533.1 - 0.19 11.9 3.2 0.98 9.6 3.2 2.2 1 0 0 1 1 1 0 Fungal ATP synthase protein 8 (A6L) Glyco_hydro_43 PF04616.14 EAQ84534.1 - 2.1e-48 165.1 0.9 2.7e-48 164.8 0.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 EAQ84534.1 - 1.8e-31 109.5 0.0 3.6e-31 108.5 0.0 1.5 2 0 0 2 2 2 1 Beta xylosidase C-terminal Concanavalin A-like domain Pec_lyase_C PF00544.19 EAQ84535.1 - 8.8e-19 67.9 13.3 8.6e-18 64.7 13.3 2.0 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 EAQ84535.1 - 1e-05 25.4 18.2 0.0003 20.7 13.1 2.2 1 1 1 2 2 2 2 Right handed beta helix region Pec_lyase_C PF00544.19 EAQ84536.1 - 4.5e-25 88.5 2.7 8.3e-25 87.6 1.8 1.8 1 1 1 2 2 2 1 Pectate lyase Beta_helix PF13229.6 EAQ84536.1 - 1.4e-05 25.0 13.0 0.00092 19.1 2.2 2.4 2 1 0 2 2 2 2 Right handed beta helix region Pectinesterase PF01095.19 EAQ84537.1 - 1.2e-24 86.6 7.4 5.8e-12 44.9 4.5 2.1 1 1 1 2 2 2 2 Pectinesterase TIL PF01826.17 EAQ84538.1 - 0.091 13.0 2.8 4 7.8 0.1 2.0 1 1 0 1 1 1 0 Trypsin Inhibitor like cysteine rich domain Fer4_6 PF12837.7 EAQ84538.1 - 4.8 7.4 9.1 6.5 7.0 0.8 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Pro-kuma_activ PF09286.11 EAQ84539.1 - 8.3e-27 94.2 0.0 2.8e-26 92.5 0.0 1.7 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Ank_2 PF12796.7 EAQ84541.1 - 5.8e-40 135.8 8.0 2.5e-08 34.4 0.0 7.5 4 2 4 8 8 8 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAQ84541.1 - 2.3e-31 107.7 4.8 6.8e-06 26.5 0.0 8.3 5 2 3 8 8 8 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAQ84541.1 - 9.6e-28 95.9 8.7 1.2e-07 31.8 0.0 9.4 9 1 1 10 10 10 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAQ84541.1 - 1.5e-24 83.4 9.0 0.0059 17.0 0.0 12.5 14 0 0 14 14 14 6 Ankyrin repeat Ank PF00023.30 EAQ84541.1 - 8.8e-20 70.2 17.7 6.3e-06 26.4 0.5 10.3 11 0 0 11 11 11 4 Ankyrin repeat AAA_16 PF13191.6 EAQ84541.1 - 1e-07 32.5 0.0 4.3e-07 30.5 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 EAQ84541.1 - 0.0042 17.0 0.0 0.016 15.1 0.0 2.0 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 EAQ84541.1 - 0.01 16.1 0.1 0.034 14.4 0.1 1.9 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EAQ84541.1 - 0.056 13.2 0.0 0.22 11.3 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein KAP_NTPase PF07693.14 EAQ84541.1 - 0.086 12.1 0.0 0.64 9.2 0.0 2.2 2 1 0 3 3 3 0 KAP family P-loop domain zf-RVT PF13966.6 EAQ84542.1 - 0.073 13.8 0.1 0.3 11.8 0.0 2.0 2 0 0 2 2 2 0 zinc-binding in reverse transcriptase NACHT PF05729.12 EAQ84544.1 - 3.4e-06 27.1 0.0 1.1e-05 25.4 0.0 2.1 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 EAQ84544.1 - 0.00027 21.2 0.0 0.0012 19.2 0.0 2.1 2 0 0 2 2 1 1 AAA domain ATPase_2 PF01637.18 EAQ84544.1 - 0.00083 19.3 0.0 0.0016 18.4 0.0 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_16 PF13191.6 EAQ84544.1 - 0.0012 19.2 0.1 0.0077 16.6 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 EAQ84544.1 - 0.0029 18.1 0.1 0.012 16.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EAQ84544.1 - 0.0077 16.0 0.0 0.019 14.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 EAQ84544.1 - 0.008 16.7 0.4 0.033 14.7 0.0 2.0 2 0 0 2 2 2 1 ABC transporter Viral_helicase1 PF01443.18 EAQ84544.1 - 0.018 14.8 0.0 0.036 13.8 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_24 PF13479.6 EAQ84544.1 - 0.025 14.3 0.1 0.11 12.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 EAQ84544.1 - 0.03 13.9 0.0 0.048 13.2 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 EAQ84544.1 - 0.03 14.5 0.0 0.086 13.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EAQ84544.1 - 0.045 14.1 0.1 0.11 12.9 0.1 1.6 1 0 0 1 1 1 0 RNA helicase MMR_HSR1 PF01926.23 EAQ84544.1 - 0.054 13.6 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF2267 PF10025.9 EAQ84544.1 - 0.062 13.6 0.4 0.42 10.9 0.0 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2267) NTPase_1 PF03266.15 EAQ84544.1 - 0.09 12.7 0.1 0.17 11.8 0.1 1.4 1 0 0 1 1 1 0 NTPase NB-ARC PF00931.22 EAQ84544.1 - 0.16 11.1 0.0 0.91 8.6 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain Parvo_NS1 PF01057.17 EAQ84544.1 - 0.18 10.9 0.0 0.34 10.0 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 MeaB PF03308.16 EAQ84544.1 - 0.2 10.6 0.0 0.4 9.6 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB zf-RVT PF13966.6 EAQ84545.1 - 0.056 14.2 0.0 0.2 12.4 0.0 1.9 2 0 0 2 2 2 0 zinc-binding in reverse transcriptase DUF1772 PF08592.11 EAQ84549.1 - 0.16 12.3 3.0 0.32 11.3 1.8 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) Copper-fist PF00649.18 EAQ84553.1 - 0.071 12.6 0.5 0.14 11.7 0.5 1.4 1 0 0 1 1 1 0 Copper fist DNA binding domain PIF1 PF05970.14 EAQ84557.1 - 4.3e-29 101.8 0.0 1.3e-22 80.5 0.0 2.1 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 EAQ84557.1 - 4.2e-14 52.7 0.0 1.1e-13 51.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAQ84557.1 - 1.4e-06 28.7 0.0 3.3e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain Herpes_Helicase PF02689.14 EAQ84557.1 - 0.00063 17.8 0.0 0.0014 16.6 0.0 1.5 2 0 0 2 2 2 1 Helicase UvrD_C_2 PF13538.6 EAQ84557.1 - 0.0017 18.1 0.1 0.0096 15.7 0.0 2.2 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_22 PF13401.6 EAQ84557.1 - 0.045 14.0 0.0 0.092 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 EAQ84557.1 - 0.058 13.2 0.1 5 6.8 0.0 2.4 2 1 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 EAQ84557.1 - 0.1 12.4 0.2 9.4 5.9 0.0 2.8 3 1 0 3 3 3 0 Viral (Superfamily 1) RNA helicase DUF5473 PF17567.2 EAQ84557.1 - 0.1 12.9 0.4 0.23 11.7 0.4 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5473) Torsin PF06309.11 EAQ84557.1 - 0.2 11.8 0.0 0.36 10.9 0.0 1.3 1 0 0 1 1 1 0 Torsin Glyco_hydro_10 PF00331.20 EAQ84558.1 - 1.1e-101 340.2 0.4 1.3e-101 340.0 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Beta-prism_lec PF16458.5 EAQ84558.1 - 0.011 15.7 1.0 0.18 11.8 0.3 2.4 2 0 0 2 2 2 0 Beta-prism lectin LEA_6 PF10714.9 EAQ84558.1 - 0.16 12.1 0.5 0.38 10.9 0.5 1.6 1 0 0 1 1 1 0 Late embryogenesis abundant protein 18 LepA_C PF06421.12 EAQ84559.1 - 1.8e-43 147.1 3.6 3.2e-43 146.3 3.6 1.4 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus GTP_EFTU PF00009.27 EAQ84559.1 - 6.6e-38 130.2 0.0 1.2e-37 129.4 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 EAQ84559.1 - 3.2e-18 65.5 0.0 6.2e-18 64.6 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EAQ84559.1 - 1.7e-07 31.5 0.2 3.3e-07 30.6 0.2 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 EAQ84559.1 - 1.9e-05 24.6 0.0 0.00013 21.9 0.0 2.4 2 1 0 2 2 2 1 Elongation Factor G, domain II Ras PF00071.22 EAQ84559.1 - 0.00049 19.7 0.0 0.0014 18.3 0.0 1.7 2 0 0 2 2 2 1 Ras family RF3_C PF16658.5 EAQ84559.1 - 0.0089 15.8 0.0 0.033 14.0 0.0 2.0 2 0 0 2 2 2 1 Class II release factor RF3, C-terminal domain SRPRB PF09439.10 EAQ84559.1 - 0.13 11.7 0.1 0.41 10.1 0.0 1.8 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit MIT PF04212.18 EAQ84560.1 - 1.3e-10 41.2 0.7 3e-10 40.0 0.7 1.6 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Dimer_Tnp_hAT PF05699.14 EAQ84561.1 - 2e-17 62.8 0.2 2e-17 62.8 0.2 1.8 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region RVT_1 PF00078.27 EAQ84562.1 - 0.0055 16.3 0.0 0.0086 15.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Glyco_transf_25 PF01755.17 EAQ84563.1 - 6.7e-11 42.4 0.0 5e-10 39.6 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) Yae1_N PF09811.9 EAQ84565.1 - 0.00068 19.3 2.4 0.00068 19.3 2.4 1.8 2 0 0 2 2 2 1 Essential protein Yae1, N terminal Mfp-3 PF04202.13 EAQ84565.1 - 0.18 12.2 1.9 0.28 11.6 1.9 1.4 1 0 0 1 1 1 0 Foot protein 3 CAP59_mtransfer PF11735.8 EAQ84568.1 - 6.6e-68 229.0 0.0 8.1e-68 228.7 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Na_Ca_ex PF01699.24 EAQ84569.1 - 7.7e-27 94.1 21.8 9.2e-14 51.7 8.9 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF1772 PF08592.11 EAQ84569.1 - 0.48 10.7 0.1 0.48 10.7 0.1 3.0 3 1 1 4 4 4 0 Domain of unknown function (DUF1772) Zip PF02535.22 EAQ84569.1 - 1.8 7.7 9.3 4.4 6.4 6.5 2.3 1 1 1 2 2 2 0 ZIP Zinc transporter SPX PF03105.19 EAQ84570.1 - 0.52 10.2 3.4 0.58 10.0 3.4 1.1 1 0 0 1 1 1 0 SPX domain CAP59_mtransfer PF11735.8 EAQ84571.1 - 5.9e-13 49.1 0.0 8.3e-13 48.6 0.0 1.2 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Glyco_hydro_18 PF00704.28 EAQ84573.1 - 1.8e-71 241.4 2.8 3e-71 240.7 2.8 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 EAQ84573.1 - 7.4e-12 45.5 16.0 7.4e-12 45.5 16.0 5.1 6 0 0 6 6 6 1 Chitin recognition protein LysM PF01476.20 EAQ84574.1 - 5.2e-16 58.4 4.2 0.032 14.3 0.0 7.5 8 0 0 8 8 8 7 LysM domain Glyco_hydro_6 PF01341.17 EAQ84577.1 - 4.6e-93 312.3 0.3 6.2e-93 311.9 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 CBM_1 PF00734.18 EAQ84577.1 - 1.8e-10 40.6 13.5 1.8e-10 40.6 13.5 2.2 2 0 0 2 2 2 1 Fungal cellulose binding domain Toxin_7 PF05980.12 EAQ84577.1 - 0.081 13.2 7.3 0.17 12.1 7.3 1.6 1 0 0 1 1 1 0 Toxin 7 Barwin PF00967.17 EAQ84578.1 - 0.12 12.2 0.2 0.19 11.6 0.2 1.3 1 1 0 1 1 1 0 Barwin family RVT_1 PF00078.27 EAQ84580.1 - 2.1e-48 164.8 0.0 3.2e-48 164.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pkinase PF00069.25 EAQ84581.1 - 8.9e-08 31.8 0.0 0.00036 20.0 0.0 3.1 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ84581.1 - 0.00041 19.7 0.0 0.088 12.1 0.0 3.0 3 0 0 3 3 3 2 Protein tyrosine kinase p450 PF00067.22 EAQ84582.1 - 4.2e-09 35.7 0.0 4.2e-06 25.8 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 Mito_fiss_reg PF05308.11 EAQ84582.1 - 0.13 12.3 0.5 0.21 11.6 0.5 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator PRIMA1 PF16101.5 EAQ84582.1 - 9.2 6.3 7.3 17 5.5 7.3 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Pkinase PF00069.25 EAQ84583.1 - 0.00011 21.7 0.0 0.12 11.7 0.0 3.2 3 0 0 3 3 3 2 Protein kinase domain CDC45 PF02724.14 EAQ84583.1 - 0.092 11.0 12.9 0.12 10.6 12.9 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF572 PF04502.13 EAQ84583.1 - 0.57 9.7 14.2 0.86 9.2 14.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) XRN_N PF03159.18 EAQ84583.1 - 0.72 9.2 5.3 1.2 8.4 5.3 1.3 1 0 0 1 1 1 0 XRN 5'-3' exonuclease N-terminus DDHD PF02862.17 EAQ84583.1 - 1.8 8.7 4.0 2.6 8.1 4.0 1.2 1 0 0 1 1 1 0 DDHD domain Merozoite_SPAM PF07133.11 EAQ84583.1 - 4.7 7.2 31.9 7.8 6.4 31.9 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) DASH_Spc19 PF08287.11 EAQ84583.1 - 7.2 6.5 19.4 15 5.5 19.4 1.4 1 0 0 1 1 1 0 Spc19 TRAP_alpha PF03896.16 EAQ84583.1 - 7.2 5.7 11.8 11 5.1 11.8 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Nop14 PF04147.12 EAQ84583.1 - 10 4.2 22.5 13 3.8 22.5 1.1 1 0 0 1 1 1 0 Nop14-like family Aldo_ket_red PF00248.21 EAQ84585.1 - 1.7e-29 103.0 0.0 1.4e-14 54.0 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family HET PF06985.11 EAQ84586.1 - 0.25 11.7 2.1 12 6.3 1.3 2.7 1 1 1 2 2 2 0 Heterokaryon incompatibility protein (HET) Amidoligase_2 PF12224.8 EAQ84589.1 - 1e-08 35.2 0.0 1.6e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 Putative amidoligase enzyme DUF4719 PF15843.5 EAQ84589.1 - 2.1 8.4 0.0 2.1 8.4 0.0 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4719) MFS_1 PF07690.16 EAQ84590.1 - 1.3e-13 50.7 48.0 1.3e-13 50.7 48.0 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_115 PF15979.5 EAQ84591.1 - 6.3e-126 420.4 0.6 8.3e-126 420.0 0.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 115 GH115_C PF17829.1 EAQ84591.1 - 2.2e-05 24.4 0.0 4.6e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Gylcosyl hydrolase family 115 C-terminal domain DUF4662 PF15578.6 EAQ84591.1 - 0.16 11.8 0.1 0.66 9.7 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4662) COesterase PF00135.28 EAQ84592.1 - 3.1e-63 214.4 0.0 6.6e-58 196.8 0.0 2.1 1 1 1 2 2 2 2 Carboxylesterase family Ank_2 PF12796.7 EAQ84592.1 - 1.8e-10 41.2 0.0 5.7e-10 39.6 0.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAQ84592.1 - 3.4e-07 30.4 0.1 1.3e-06 28.5 0.1 2.2 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAQ84592.1 - 6.2e-07 29.8 0.0 3.3e-05 24.3 0.0 2.7 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EAQ84592.1 - 7.2e-07 29.4 0.0 0.023 15.2 0.0 4.2 3 1 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 EAQ84592.1 - 1.4e-06 28.1 0.1 0.53 11.0 0.0 3.9 3 0 0 3 3 3 2 Ankyrin repeat Abhydrolase_3 PF07859.13 EAQ84592.1 - 3.9e-06 26.9 0.0 6.4e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EAQ84592.1 - 0.0004 21.1 0.7 0.0004 21.1 0.7 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 EAQ84592.1 - 0.046 13.2 0.0 0.081 12.4 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family LIP PF03583.14 EAQ84592.1 - 0.22 10.8 0.8 0.31 10.3 0.2 1.5 2 0 0 2 2 2 0 Secretory lipase Beta_helix PF13229.6 EAQ84597.1 - 0.00023 21.0 25.3 0.0043 16.9 17.4 2.5 1 1 2 3 3 3 3 Right handed beta helix region DUF5434 PF17502.2 EAQ84601.1 - 0.021 14.9 0.2 0.033 14.2 0.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5434) HJURP_C PF12347.8 EAQ84602.1 - 0.033 14.2 0.0 0.098 12.7 0.0 1.8 1 0 0 1 1 1 0 Holliday junction regulator protein family C-terminal repeat GCN5L1 PF06320.13 EAQ84602.1 - 0.11 12.7 0.1 0.21 11.7 0.1 1.4 1 0 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) DUF4419 PF14388.6 EAQ84603.1 - 6.1e-97 324.7 0.0 7.2e-97 324.4 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) IlvB_leader PF08049.11 EAQ84603.1 - 0.057 13.4 2.5 0.15 12.0 2.5 1.7 1 0 0 1 1 1 0 IlvB leader peptide DUF768 PF05589.11 EAQ84603.1 - 0.069 13.2 0.1 0.14 12.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF768) Peptidase_S8 PF00082.22 EAQ84604.1 - 9.8e-08 31.6 0.8 1.4e-07 31.1 0.8 1.2 1 0 0 1 1 1 1 Subtilase family LBP_BPI_CETP PF01273.25 EAQ84605.1 - 0.098 12.3 0.0 0.18 11.4 0.0 1.4 1 1 0 1 1 1 0 LBP / BPI / CETP family, N-terminal domain Tic110 PF16940.5 EAQ84606.1 - 5.7 5.3 4.8 7.7 4.9 4.8 1.1 1 0 0 1 1 1 0 Chloroplast envelope transporter Glyco_hydro_61 PF03443.14 EAQ84607.1 - 1.4e-19 70.8 0.0 1.6e-19 70.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CDH-cyt PF16010.5 EAQ84608.1 - 3.5e-62 209.3 1.6 6.7e-62 208.4 1.6 1.5 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase GMC_oxred_N PF00732.19 EAQ84608.1 - 3.6e-20 72.5 0.0 1e-19 71.0 0.0 1.8 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EAQ84608.1 - 6.6e-19 68.9 0.1 1.3e-18 67.9 0.1 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 EAQ84608.1 - 7.7e-10 38.4 0.4 0.0002 20.5 0.1 2.5 3 0 0 3 3 3 2 FAD binding domain NAD_binding_8 PF13450.6 EAQ84608.1 - 8.9e-05 22.7 0.0 0.00027 21.1 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EAQ84608.1 - 0.00014 21.3 0.0 0.00023 20.5 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DOMON PF03351.17 EAQ84608.1 - 0.00039 20.6 0.0 0.00092 19.4 0.0 1.6 1 0 0 1 1 1 1 DOMON domain DAO PF01266.24 EAQ84608.1 - 0.00084 19.0 0.0 0.016 14.8 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EAQ84608.1 - 0.0011 17.7 0.1 0.0017 17.2 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 EAQ84608.1 - 0.0012 19.3 0.0 0.1 13.1 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EAQ84608.1 - 0.0058 16.0 0.0 0.059 12.7 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EAQ84608.1 - 0.016 14.3 0.0 0.031 13.3 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 EAQ84608.1 - 0.019 14.2 0.4 0.03 13.6 0.4 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EAQ84608.1 - 0.038 13.2 0.1 0.12 11.6 0.1 1.8 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.17 EAQ84608.1 - 0.07 12.4 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.22 EAQ84608.1 - 0.17 10.9 0.0 0.27 10.3 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A TrkA_N PF02254.18 EAQ84608.1 - 0.18 12.1 0.0 0.38 11.0 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain SWI-SNF_Ssr4 PF08549.10 EAQ84609.1 - 0.41 9.2 6.3 0.48 9.0 6.3 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) Hamartin PF04388.12 EAQ84609.1 - 5.3 5.6 7.9 6.7 5.2 7.9 1.1 1 0 0 1 1 1 0 Hamartin protein Dimer_Tnp_hAT PF05699.14 EAQ84610.1 - 5.8e-06 26.0 0.0 1.4e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region FF PF01846.19 EAQ84610.1 - 0.12 12.5 0.2 12 6.2 0.0 3.0 2 0 0 2 2 2 0 FF domain CDH-cyt PF16010.5 EAQ84611.1 - 1.3e-15 57.6 0.1 1.4e-15 57.4 0.1 1.1 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase Exo_endo_phos_2 PF14529.6 EAQ84612.1 - 1.4e-20 73.3 2.7 1.6e-20 73.1 0.1 2.5 4 0 0 4 4 4 1 Endonuclease-reverse transcriptase zf-CCHC PF00098.23 EAQ84612.1 - 0.0031 17.5 2.5 0.0031 17.5 2.5 2.4 2 0 0 2 2 2 1 Zinc knuckle Exo_endo_phos PF03372.23 EAQ84612.1 - 0.019 14.5 0.1 0.035 13.6 0.1 1.5 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family SlyX PF04102.12 EAQ84612.1 - 0.026 15.1 7.3 0.036 14.7 5.3 2.2 1 1 1 2 2 2 0 SlyX DUF948 PF06103.11 EAQ84612.1 - 0.032 14.5 0.6 0.074 13.3 0.6 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) SEEK1 PF15357.6 EAQ84612.1 - 0.1 12.7 0.4 0.23 11.6 0.4 1.5 1 0 0 1 1 1 0 Psoriasis susceptibility 1 candidate 1 DUF1672 PF07901.11 EAQ84612.1 - 0.41 9.9 1.2 1.3 8.3 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1672) ADIP PF11559.8 EAQ84612.1 - 2 8.5 9.0 0.25 11.4 3.3 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Phage_lysis PF03245.13 EAQ84612.1 - 4.9 7.3 9.3 0.28 11.3 2.8 2.2 3 0 0 3 3 3 0 Bacteriophage Rz lysis protein Acetyltransf_13 PF13880.6 EAQ84613.1 - 0.066 13.2 0.1 0.15 12.1 0.1 1.5 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase RNA_pol_Rpb1_2 PF00623.20 EAQ84614.1 - 8.5e-73 244.0 0.2 2e-72 242.8 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_5 PF04998.17 EAQ84614.1 - 5.1e-60 203.2 0.1 7.8e-60 202.6 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.12 EAQ84614.1 - 1.5e-44 152.6 0.0 6.1e-40 137.5 0.0 2.4 1 1 1 2 2 2 2 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_3 PF04983.18 EAQ84614.1 - 1.1e-35 123.0 0.0 4.1e-35 121.0 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 EAQ84614.1 - 3.2e-32 110.7 0.5 1.1e-31 109.0 0.1 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 DDHD PF02862.17 EAQ84615.1 - 2.8e-64 217.4 4.0 1.6e-63 214.8 0.3 3.1 2 1 0 2 2 2 1 DDHD domain LIDHydrolase PF10230.9 EAQ84615.1 - 0.019 14.6 0.0 0.052 13.1 0.0 1.7 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase Abhydrolase_6 PF12697.7 EAQ84615.1 - 0.13 12.9 0.0 0.22 12.1 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family zf-RING_UBOX PF13445.6 EAQ84616.1 - 0.0067 16.4 4.4 0.015 15.3 4.4 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 EAQ84616.1 - 0.014 15.7 9.8 0.038 14.3 9.8 1.8 1 1 0 1 1 1 0 Ring finger domain zf-C3HC4_4 PF15227.6 EAQ84616.1 - 0.023 14.8 3.7 0.054 13.7 3.7 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Ank_2 PF12796.7 EAQ84616.1 - 0.049 14.2 0.0 0.27 11.8 0.0 2.0 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) zf-RING_4 PF14570.6 EAQ84616.1 - 0.05 13.4 0.6 0.05 13.4 0.6 1.8 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.6 EAQ84616.1 - 0.09 12.7 3.8 0.16 12.0 3.8 1.4 1 0 0 1 1 1 0 zinc-RING finger domain DUF3927 PF13064.6 EAQ84616.1 - 0.11 12.5 0.3 0.2 11.6 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3927) zf-rbx1 PF12678.7 EAQ84616.1 - 0.36 11.2 4.5 0.6 10.5 4.5 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger domain CH PF00307.31 EAQ84617.1 - 2.1e-65 217.7 0.0 1e-18 67.5 0.0 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.6 EAQ84617.1 - 2.2e-05 24.8 0.3 0.00028 21.3 0.1 2.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 EAQ84617.1 - 0.0025 17.6 0.4 0.13 12.3 0.1 2.8 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 EAQ84617.1 - 0.0047 16.4 0.9 0.44 10.2 0.1 3.0 2 0 0 2 2 2 1 EF hand tRNA-synt_1b PF00579.25 EAQ84618.1 - 1.2e-58 198.7 0.0 1.5e-58 198.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) MBOAT PF03062.19 EAQ84619.1 - 5.6e-45 154.2 17.0 5.6e-45 154.2 17.0 2.3 3 0 0 3 3 3 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 EAQ84619.1 - 1.3e-05 25.4 3.7 3.3e-05 24.1 3.7 1.6 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family RRM_1 PF00076.22 EAQ84620.1 - 2.1e-11 43.5 0.0 2.8e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EAQ84620.1 - 8.5e-05 22.5 0.0 0.00012 22.0 0.0 1.2 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Mito_carr PF00153.27 EAQ84621.1 - 1.6e-51 172.2 7.6 1.1e-23 83.0 0.1 3.4 4 0 0 4 4 4 3 Mitochondrial carrier protein Serine_protease PF18405.1 EAQ84621.1 - 0.00016 20.9 0.8 0.0043 16.3 0.0 2.9 1 1 1 2 2 2 1 Gammaproteobacterial serine protease PT-VENN PF04829.13 EAQ84621.1 - 0.17 12.0 2.1 9.7 6.4 0.0 2.7 3 0 0 3 3 3 0 Pre-toxin domain with VENN motif OST3_OST6 PF04756.13 EAQ84622.1 - 2.5e-106 355.3 0.0 3.4e-106 354.9 0.0 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family UbiA PF01040.18 EAQ84622.1 - 0.035 13.4 6.8 0.083 12.2 6.8 1.6 1 0 0 1 1 1 0 UbiA prenyltransferase family Thioredoxin PF00085.20 EAQ84622.1 - 0.059 13.4 0.0 0.094 12.7 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin 7TMR-DISM_7TM PF07695.11 EAQ84622.1 - 0.065 13.1 10.4 2.7 7.8 10.9 2.2 1 1 1 2 2 2 0 7TM diverse intracellular signalling DUF2242 PF10001.9 EAQ84622.1 - 0.14 12.3 0.0 0.26 11.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2242) CPBP PF02517.16 EAQ84622.1 - 0.49 10.8 3.8 1.3 9.5 3.8 1.9 1 1 0 1 1 1 0 CPBP intramembrane metalloprotease MerC PF03203.14 EAQ84622.1 - 0.89 10.0 7.4 2.9 8.4 0.1 2.6 3 0 0 3 3 3 0 MerC mercury resistance protein FtsJ PF01728.19 EAQ84623.1 - 1.1e-44 152.7 0.0 3.4e-44 151.1 0.0 1.9 2 0 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.6 EAQ84623.1 - 0.015 15.2 0.0 0.23 11.3 0.0 2.5 1 1 0 1 1 1 0 Methyltransferase domain PCYCGC PF13798.6 EAQ84623.1 - 6.6 6.6 5.4 4.6 7.1 1.1 2.5 2 0 0 2 2 2 0 Protein of unknown function with PCYCGC motif Ribosomal_L18 PF17135.4 EAQ84624.1 - 1.4e-92 308.3 5.3 1.6e-92 308.1 5.3 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 EAQ84624.1 - 0.00042 21.0 0.4 0.0011 19.6 0.4 1.9 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A TBPIP PF07106.13 EAQ84624.1 - 0.092 12.7 0.1 0.19 11.7 0.1 1.6 1 0 0 1 1 1 0 TBPIP/Hop2 winged helix domain Glyco_hydro_6 PF01341.17 EAQ84625.1 - 5.8e-101 338.2 0.2 7.5e-101 337.9 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 Adap_comp_sub PF00928.21 EAQ84626.1 - 3.9e-66 223.1 0.0 5.1e-66 222.7 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EAQ84626.1 - 4.9e-05 23.3 0.0 7.7e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain ChapFlgA_N PF17656.1 EAQ84626.1 - 0.014 15.6 0.7 2.1 8.6 0.0 3.1 3 0 0 3 3 3 0 FlgA N-terminal domain Hexapep PF00132.24 EAQ84627.1 - 1.2e-13 50.2 18.5 2.7e-09 36.4 2.3 3.4 3 0 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Mac PF12464.8 EAQ84627.1 - 1.5e-12 47.6 0.0 3.2e-12 46.5 0.0 1.6 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep_2 PF14602.6 EAQ84627.1 - 1.7e-10 40.5 20.5 7e-08 32.1 1.2 2.9 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Zn_clus PF00172.18 EAQ84627.1 - 1.4e-08 34.7 9.7 2.8e-08 33.7 9.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SANT_DAMP1_like PF16282.5 EAQ84629.1 - 1.8e-29 101.7 1.1 3.4e-29 100.9 1.1 1.4 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_6 PF13921.6 EAQ84629.1 - 0.015 15.6 0.0 0.041 14.1 0.0 1.9 1 1 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EAQ84629.1 - 0.069 13.3 1.0 0.5 10.6 1.1 2.6 2 1 0 2 2 2 0 Myb-like DNA-binding domain RNA_pol_Rpc4 PF05132.14 EAQ84629.1 - 0.1 13.1 0.2 0.1 13.1 0.2 3.4 3 1 1 4 4 4 0 RNA polymerase III RPC4 EMP24_GP25L PF01105.24 EAQ84630.1 - 3.3e-52 177.1 0.0 3.8e-52 176.9 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Pkinase PF00069.25 EAQ84631.1 - 3.2e-27 95.6 0.0 4.4e-27 95.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ84631.1 - 8.6e-14 51.4 0.0 1.2e-13 51.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EAQ84631.1 - 1.3e-06 27.5 0.0 1.8e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Nucleoporin_C PF03177.14 EAQ84632.1 - 4.3e-180 600.4 6.0 5.5e-180 600.0 6.0 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.11 EAQ84632.1 - 1.1e-104 350.6 0.0 1.5e-104 350.2 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Clathrin PF00637.20 EAQ84632.1 - 0.11 12.3 0.1 1.1 9.2 0.1 2.5 1 1 0 1 1 1 0 Region in Clathrin and VPS Erythro_esteras PF05139.14 EAQ84632.1 - 9.7 5.9 11.5 0.75 9.5 6.3 1.7 2 0 0 2 2 2 0 Erythromycin esterase AFG1_ATPase PF03969.16 EAQ84633.1 - 1e-25 90.5 0.0 6.4e-20 71.3 0.0 3.1 3 0 0 3 3 3 3 AFG1-like ATPase PQQ_2 PF13360.6 EAQ84633.1 - 0.099 12.2 0.1 0.17 11.4 0.1 1.3 1 0 0 1 1 1 0 PQQ-like domain Glyco_transf_90 PF05686.12 EAQ84634.1 - 2e-22 79.7 0.0 7.3e-19 67.9 0.0 2.1 2 0 0 2 2 2 2 Glycosyl transferase family 90 Acyl_transf_1 PF00698.21 EAQ84635.1 - 4e-20 72.6 0.2 2.7e-16 60.0 0.2 2.3 1 1 0 1 1 1 1 Acyl transferase domain DUF2458 PF10454.9 EAQ84635.1 - 0.0003 20.5 0.0 0.00049 19.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2458) ROS_MUCR PF05443.11 EAQ84635.1 - 0.11 12.6 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 ROS/MUCR transcriptional regulator protein ECR1_N PF14382.6 EAQ84636.1 - 6.3e-16 57.9 2.6 8.1e-16 57.5 1.2 2.0 2 0 0 2 2 2 1 Exosome complex exonuclease RRP4 N-terminal region S1 PF00575.23 EAQ84636.1 - 0.055 13.8 0.3 18 5.8 0.2 2.5 2 0 0 2 2 2 0 S1 RNA binding domain EXOSC1 PF10447.9 EAQ84636.1 - 0.12 13.0 0.1 1.1 9.9 0.1 2.4 2 0 0 2 2 2 0 Exosome component EXOSC1/CSL4 Aldedh PF00171.22 EAQ84637.1 - 3.1e-71 240.3 0.1 5.2e-51 173.6 0.0 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family MRP-S28 PF10213.9 EAQ84638.1 - 3.6e-49 166.4 0.9 8e-49 165.3 0.2 1.9 2 0 0 2 2 2 1 Mitochondrial ribosomal subunit protein TerB PF05099.13 EAQ84638.1 - 0.035 14.1 1.5 0.13 12.2 0.6 2.2 1 1 1 2 2 2 0 Tellurite resistance protein TerB Glyco_tran_28_C PF04101.16 EAQ84639.1 - 2.6e-14 53.5 0.0 2.6e-14 53.5 0.0 2.5 2 1 0 2 2 1 1 Glycosyltransferase family 28 C-terminal domain AAA_23 PF13476.6 EAQ84639.1 - 0.00011 22.7 0.1 0.00013 22.5 0.1 1.2 1 0 0 1 1 1 1 AAA domain DDHD PF02862.17 EAQ84639.1 - 0.0084 16.3 1.1 0.012 15.8 1.1 1.3 1 0 0 1 1 1 1 DDHD domain Presenilin PF01080.17 EAQ84639.1 - 0.026 13.3 4.4 0.037 12.8 4.4 1.2 1 0 0 1 1 1 0 Presenilin Connexin PF00029.19 EAQ84639.1 - 0.042 13.6 0.4 0.058 13.1 0.4 1.2 1 0 0 1 1 1 0 Connexin VIR_N PF15912.5 EAQ84639.1 - 0.092 12.3 7.4 0.26 10.9 7.4 1.6 1 1 0 1 1 1 0 Virilizer, N-terminal Neur_chan_memb PF02932.16 EAQ84639.1 - 0.11 12.5 0.7 0.16 12.0 0.7 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CPSF100_C PF13299.6 EAQ84639.1 - 0.17 12.1 3.8 0.33 11.1 3.8 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal TFIIA PF03153.13 EAQ84639.1 - 0.42 10.6 28.9 0.75 9.7 28.9 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pex14_N PF04695.13 EAQ84639.1 - 0.53 10.9 24.2 9.2 6.9 23.0 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Peroxin-13_N PF04088.13 EAQ84639.1 - 0.69 10.2 3.0 1.3 9.3 3.0 1.4 1 0 0 1 1 1 0 Peroxin 13, N-terminal region ORC_WH_C PF18137.1 EAQ84639.1 - 0.86 9.7 8.6 1.5 8.9 8.6 1.4 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal Spt20 PF12090.8 EAQ84639.1 - 1.1 8.9 38.1 1.9 8.1 38.1 1.3 1 0 0 1 1 1 0 Spt20 family Suf PF05843.14 EAQ84639.1 - 1.9 8.4 14.4 3.3 7.6 14.4 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) AIF_C PF14721.6 EAQ84639.1 - 2 8.7 6.5 3.6 7.9 6.5 1.3 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term eIF-3_zeta PF05091.12 EAQ84639.1 - 2.4 7.1 15.1 3.3 6.6 15.1 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) TERB2 PF15101.6 EAQ84639.1 - 2.7 8.0 16.7 4.7 7.2 16.7 1.3 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Orf78 PF06024.12 EAQ84639.1 - 2.9 8.2 5.3 5.5 7.4 5.3 1.3 1 0 0 1 1 1 0 Orf78 (ac78) Band_3_cyto PF07565.13 EAQ84639.1 - 3.1 7.5 7.3 5 6.8 7.3 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF702 PF05142.12 EAQ84639.1 - 3.2 8.2 12.2 61 4.1 11.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF702) DUF1980 PF09323.10 EAQ84639.1 - 3.9 7.4 5.4 6 6.7 5.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) EIIBC-GUT_N PF03612.14 EAQ84639.1 - 4.8 6.9 10.2 11 5.7 10.2 1.5 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Med15 PF09606.10 EAQ84639.1 - 5.2 5.6 28.6 7.8 5.0 28.6 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal RPA43_OB PF17875.1 EAQ84639.1 - 5.3 7.7 12.6 11 6.7 12.6 1.4 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I FHIPEP PF00771.20 EAQ84639.1 - 7.2 4.9 6.5 10 4.4 6.5 1.1 1 0 0 1 1 1 0 FHIPEP family DUF4175 PF13779.6 EAQ84639.1 - 8.6 4.1 28.7 12 3.6 28.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) WD40 PF00400.32 EAQ84640.1 - 1.5e-28 98.4 29.9 0.00015 22.5 0.5 9.9 10 0 0 10 10 10 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAQ84640.1 - 1.4e-12 47.7 7.5 0.19 12.1 0.0 7.6 4 3 5 9 9 9 4 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 EAQ84640.1 - 0.0051 16.7 0.2 5.2 7.1 0.0 4.0 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Lactonase PF10282.9 EAQ84640.1 - 0.022 14.0 0.1 0.072 12.3 0.1 2.0 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller Ge1_WD40 PF16529.5 EAQ84640.1 - 0.029 13.3 3.9 12 4.7 0.1 4.2 3 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EAQ84640.1 - 0.16 10.6 0.0 1.2 7.7 0.0 2.3 2 0 0 2 2 2 0 Nucleoporin Nup120/160 RRM_1 PF00076.22 EAQ84642.1 - 2.8e-16 59.1 0.0 4.5e-16 58.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GRP PF07172.11 EAQ84642.1 - 0.016 15.9 9.7 0.038 14.7 9.7 1.7 1 0 0 1 1 1 0 Glycine rich protein family Nup35_RRM_2 PF14605.6 EAQ84642.1 - 0.11 12.5 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif DivIC PF04977.15 EAQ84642.1 - 0.34 10.7 3.2 0.51 10.2 3.2 1.2 1 0 0 1 1 1 0 Septum formation initiator HECT PF00632.25 EAQ84643.1 - 2.6e-83 280.0 0.0 1.1e-69 235.3 0.0 2.3 1 1 1 2 2 2 2 HECT-domain (ubiquitin-transferase) WW PF00397.26 EAQ84643.1 - 2.7e-34 116.9 24.0 1.8e-12 47.1 5.3 4.1 4 0 0 4 4 4 3 WW domain C2 PF00168.30 EAQ84643.1 - 1.8e-17 63.5 0.1 6.1e-17 61.8 0.1 1.9 1 0 0 1 1 1 1 C2 domain Amidohydro_3 PF07969.11 EAQ84644.1 - 5.7e-56 190.9 0.0 7e-56 190.6 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 EAQ84644.1 - 0.061 12.6 0.0 0.079 12.3 0.0 1.4 1 1 0 1 1 1 0 Amidohydrolase family SPX PF03105.19 EAQ84645.1 - 5.4e-10 39.8 11.6 0.00011 22.2 0.1 2.9 1 1 2 3 3 3 2 SPX domain CcmD PF04995.14 EAQ84645.1 - 0.084 13.0 0.1 0.084 13.0 0.1 2.1 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) Mpp10 PF04006.12 EAQ84647.1 - 9.2e-108 361.3 66.4 4.1e-107 359.2 66.4 1.8 1 1 0 1 1 1 1 Mpp10 protein DUF445 PF04286.12 EAQ84647.1 - 0.15 11.9 2.5 1.9 8.2 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF445) Oxidored_q6 PF01058.22 EAQ84648.1 - 5.5e-22 78.0 0.0 7.6e-22 77.5 0.0 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Tubulin_C PF03953.17 EAQ84649.1 - 4e-43 146.6 0.1 8.3e-43 145.6 0.1 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain PLDc PF00614.22 EAQ84650.1 - 3.4e-16 58.7 0.4 2.4e-07 30.7 0.3 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 EAQ84650.1 - 1.6e-13 50.7 0.0 1.7e-07 31.2 0.0 2.9 2 1 0 2 2 2 2 PLD-like domain PX PF00787.24 EAQ84650.1 - 5.5e-07 29.6 0.1 1.8e-05 24.6 0.1 2.8 1 1 0 1 1 1 1 PX domain COQ7 PF03232.13 EAQ84651.1 - 7.5e-70 234.2 0.4 9.2e-70 233.9 0.4 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.17 EAQ84651.1 - 0.00038 20.9 0.0 0.00073 19.9 0.0 1.4 1 0 0 1 1 1 1 Rubrerythrin DUF4611 PF15387.6 EAQ84651.1 - 0.008 16.4 0.1 3.5 7.9 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4611) Crr6 PF08847.11 EAQ84651.1 - 0.094 12.4 0.1 2.4 7.8 0.0 2.2 1 1 1 2 2 2 0 Chlororespiratory reduction 6 DUF4632 PF15451.6 EAQ84651.1 - 0.095 12.8 0.1 0.25 11.4 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4632) Mito_fiss_reg PF05308.11 EAQ84651.1 - 1.3 9.0 7.5 1.9 8.5 7.5 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator Shisa PF13908.6 EAQ84651.1 - 5.3 7.2 8.4 8 6.7 8.4 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Plus-3 PF03126.18 EAQ84652.1 - 2.6e-29 101.9 0.0 5.9e-29 100.8 0.0 1.6 1 0 0 1 1 1 1 Plus-3 domain Alba PF01918.21 EAQ84654.1 - 3.2e-12 46.1 0.0 4.9e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 Alba DUF202 PF02656.15 EAQ84655.1 - 1.2e-15 57.6 2.8 1.2e-15 57.6 2.8 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Tctex-1 PF03645.13 EAQ84656.1 - 2e-16 60.1 0.0 2.8e-16 59.6 0.0 1.2 1 0 0 1 1 1 1 Tctex-1 family Macoilin PF09726.9 EAQ84658.1 - 4.5 5.7 10.4 5.8 5.4 10.4 1.1 1 0 0 1 1 1 0 Macoilin family zf-C2H2 PF00096.26 EAQ84660.1 - 7.6e-09 35.6 8.2 0.00019 21.7 0.5 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EAQ84660.1 - 0.00011 22.7 7.1 0.065 14.1 0.8 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.12 EAQ84660.1 - 1.3 9.4 3.0 1.3 9.3 0.4 2.2 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2HC_2 PF13913.6 EAQ84660.1 - 2.1 8.3 4.6 0.37 10.7 0.7 1.9 2 0 0 2 2 2 0 zinc-finger of a C2HC-type FTHFS PF01268.19 EAQ84661.1 - 3.5e-254 844.1 0.0 4.8e-254 843.7 0.0 1.2 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 EAQ84661.1 - 3.9e-68 227.8 2.7 4.8e-68 227.5 0.5 2.1 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 EAQ84661.1 - 1.7e-37 128.2 0.1 3.4e-37 127.2 0.1 1.5 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Glyco_trans_1_4 PF13692.6 EAQ84661.1 - 0.063 13.7 0.0 0.18 12.2 0.0 1.8 1 0 0 1 1 1 0 Glycosyl transferases group 1 CbiA PF01656.23 EAQ84661.1 - 0.11 12.6 0.0 1.6 8.8 0.1 2.6 3 1 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain WD40 PF00400.32 EAQ84662.1 - 1.7e-27 95.1 1.2 5e-09 36.6 0.1 6.3 6 1 1 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAQ84662.1 - 2.1e-15 56.8 0.0 1.2e-06 28.7 0.0 4.1 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 EAQ84662.1 - 4.8e-05 22.6 0.2 0.011 14.9 0.0 2.2 1 1 1 2 2 2 2 Coatomer WD associated region Nup160 PF11715.8 EAQ84662.1 - 0.00052 18.8 0.1 0.0011 17.7 0.1 1.4 1 1 0 1 1 1 1 Nucleoporin Nup120/160 eIF2A PF08662.11 EAQ84662.1 - 0.0012 18.7 0.1 2.8 7.8 0.0 3.4 1 1 3 4 4 4 1 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.11 EAQ84662.1 - 0.017 13.9 0.2 0.078 11.7 0.0 2.1 2 1 0 2 2 2 0 Nup133 N terminal like WD40_like PF17005.5 EAQ84662.1 - 0.019 14.3 0.1 0.21 10.9 0.2 2.4 2 1 1 3 3 3 0 WD40-like domain PQQ_2 PF13360.6 EAQ84662.1 - 0.025 14.1 0.0 0.14 11.8 0.0 2.1 1 1 0 1 1 1 0 PQQ-like domain PALB2_WD40 PF16756.5 EAQ84662.1 - 0.093 11.6 0.1 4.7 6.0 0.0 2.4 2 1 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain SNF2_N PF00176.23 EAQ84663.1 - 6.6e-75 252.0 0.1 1.3e-74 251.0 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 EAQ84663.1 - 4.8e-44 149.0 1.8 1.4e-43 147.5 1.8 1.9 1 0 0 1 1 1 1 SLIDE HAND PF09110.11 EAQ84663.1 - 2.1e-39 134.7 4.6 2.1e-39 134.7 4.6 3.9 4 0 0 4 4 3 1 HAND Helicase_C PF00271.31 EAQ84663.1 - 3.6e-18 65.9 0.1 2.1e-17 63.4 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EAQ84663.1 - 4.6e-11 43.0 0.0 3.4e-10 40.2 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 EAQ84663.1 - 0.0001 21.6 0.0 0.00049 19.4 0.0 2.1 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 EAQ84663.1 - 0.00014 21.7 0.0 0.00048 20.0 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 EAQ84663.1 - 0.00082 19.1 0.0 0.0024 17.6 0.0 1.8 1 0 0 1 1 1 1 SWI2/SNF2 ATPase DUF1086 PF06461.11 EAQ84663.1 - 0.00085 19.2 0.1 0.0026 17.6 0.1 1.8 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1086) Myb_DNA-binding PF00249.31 EAQ84663.1 - 0.0039 17.4 0.1 1.1 9.5 0.0 3.2 2 1 0 2 2 2 1 Myb-like DNA-binding domain Occludin_ELL PF07303.13 EAQ84663.1 - 0.052 14.3 4.6 0.18 12.6 4.6 1.9 1 0 0 1 1 1 0 Occludin homology domain AAA_14 PF13173.6 EAQ84663.1 - 0.075 13.1 0.0 0.26 11.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain DEAD_2 PF06733.15 EAQ84663.1 - 0.1 12.2 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 DEAD_2 DUF4588 PF15251.6 EAQ84664.1 - 2.3e-06 27.6 0.1 3.9e-06 26.8 0.1 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4588) CFEM PF05730.11 EAQ84665.1 - 0.053 13.6 7.3 0.095 12.8 7.0 1.7 1 1 0 1 1 1 0 CFEM domain DUF1180 PF06679.12 EAQ84665.1 - 3.3 8.1 6.9 5.1 7.5 6.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) DUF515 PF04415.12 EAQ84665.1 - 4.1 5.7 6.8 5.9 5.2 6.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) SOG2 PF10428.9 EAQ84666.1 - 4 6.5 6.4 4.2 6.5 6.4 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein zf-RING_UBOX PF13445.6 EAQ84667.1 - 3.4e-07 30.2 2.5 3.4e-07 30.2 2.5 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 EAQ84667.1 - 7.8e-07 29.3 7.4 1.5e-06 28.4 7.4 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 EAQ84667.1 - 1.5e-06 27.9 5.5 3.3e-06 26.8 5.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EAQ84667.1 - 1.6e-06 27.9 7.1 3.1e-06 27.0 7.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EAQ84667.1 - 1.2e-05 25.1 6.8 4.3e-05 23.3 2.3 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EAQ84667.1 - 3.9e-05 23.7 6.0 0.00017 21.7 5.4 2.1 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 EAQ84667.1 - 4.2e-05 23.4 6.3 8.6e-05 22.4 6.1 1.6 1 1 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EAQ84667.1 - 0.0043 16.9 9.3 0.031 14.1 8.5 2.5 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 EAQ84667.1 - 0.056 13.5 1.3 0.12 12.4 1.3 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_10 PF16685.5 EAQ84667.1 - 0.2 11.8 5.6 0.73 10.0 5.6 1.9 1 1 0 1 1 1 0 zinc RING finger of MSL2 zf-rbx1 PF12678.7 EAQ84667.1 - 0.75 10.1 7.9 3.3 8.1 7.9 2.1 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-MIZ PF02891.20 EAQ84667.1 - 1.1 9.0 8.1 9.1 6.1 7.7 2.2 1 1 1 2 2 2 0 MIZ/SP-RING zinc finger PGA2 PF07543.12 EAQ84667.1 - 7.2 6.6 8.2 8.9 6.3 0.5 3.2 3 0 0 3 3 3 0 Protein trafficking PGA2 AMPK1_CBM PF16561.5 EAQ84668.1 - 4.5e-23 81.3 0.5 8e-23 80.5 0.5 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase UBA PF00627.31 EAQ84668.1 - 0.00058 19.7 0.1 0.031 14.2 0.0 2.5 2 0 0 2 2 2 1 UBA/TS-N domain CBM53 PF16760.5 EAQ84668.1 - 0.043 14.4 0.8 0.092 13.3 0.8 1.5 1 0 0 1 1 1 0 Starch/carbohydrate-binding module (family 53) CBM_48 PF02922.18 EAQ84668.1 - 0.058 13.8 0.2 0.13 12.6 0.2 1.5 1 0 0 1 1 1 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) NAD_binding_6 PF08030.12 EAQ84669.1 - 1.2e-20 74.2 0.0 1.8e-20 73.6 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 EAQ84669.1 - 5.6e-13 49.1 21.5 7.7e-13 48.7 15.3 2.4 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 EAQ84669.1 - 3.9e-11 43.0 0.0 1.1e-10 41.6 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 EAQ84669.1 - 0.003 18.2 0.0 0.23 12.1 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain DUF2871 PF11070.8 EAQ84669.1 - 0.27 11.5 6.2 0.6 10.4 6.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2871) Golgin_A5 PF09787.9 EAQ84671.1 - 0.00064 19.3 7.1 0.00064 19.3 7.1 2.1 2 0 0 2 2 2 1 Golgin subfamily A member 5 DUF1664 PF07889.12 EAQ84671.1 - 0.011 15.7 1.8 0.2 11.7 2.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) APG6_N PF17675.1 EAQ84671.1 - 0.02 15.4 13.2 0.02 15.4 13.2 2.5 2 1 1 3 3 3 0 Apg6 coiled-coil region Baculo_PEP_C PF04513.12 EAQ84671.1 - 0.026 14.5 0.7 0.077 13.0 0.2 1.8 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Snapin_Pallidin PF14712.6 EAQ84671.1 - 0.068 13.6 5.9 0.15 12.5 4.8 2.1 1 1 1 2 2 2 0 Snapin/Pallidin FUSC PF04632.12 EAQ84671.1 - 0.11 11.1 0.0 0.11 11.1 0.0 1.5 2 0 0 2 2 2 0 Fusaric acid resistance protein family Cob_adeno_trans PF01923.18 EAQ84671.1 - 0.12 12.5 1.5 0.27 11.4 1.5 1.5 1 0 0 1 1 1 0 Cobalamin adenosyltransferase Herpes_UL6 PF01763.16 EAQ84671.1 - 0.81 8.1 4.9 1.3 7.5 4.9 1.2 1 0 0 1 1 1 0 Herpesvirus UL6 like Fzo_mitofusin PF04799.13 EAQ84671.1 - 1 8.9 3.5 2.2 7.8 3.0 1.7 1 1 0 1 1 1 0 fzo-like conserved region TMPIT PF07851.13 EAQ84671.1 - 1.4 8.1 5.3 2.8 7.1 5.3 1.6 1 0 0 1 1 1 0 TMPIT-like protein Prefoldin_2 PF01920.20 EAQ84671.1 - 4.1 7.4 14.2 1.7 8.7 2.9 3.0 1 1 2 3 3 3 0 Prefoldin subunit Spc7 PF08317.11 EAQ84671.1 - 7.1 5.4 17.9 9.4 5.0 16.9 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein Fez1 PF06818.15 EAQ84671.1 - 7.8 6.9 25.9 0.048 14.1 14.6 2.6 2 1 1 3 3 3 0 Fez1 RTA1 PF04479.13 EAQ84672.1 - 2e-28 99.5 11.6 2e-28 99.5 11.6 2.0 1 1 1 2 2 2 2 RTA1 like protein PGAP1 PF07819.13 EAQ84674.1 - 2.4e-08 34.0 0.0 3.7e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein LCAT PF02450.15 EAQ84674.1 - 1.5e-06 27.7 0.0 2.3e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF676 PF05057.14 EAQ84674.1 - 2.6e-06 27.1 0.0 4e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 EAQ84674.1 - 6e-06 26.3 0.0 1.1e-05 25.5 0.0 1.4 2 0 0 2 2 2 1 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.20 EAQ84674.1 - 4.6e-05 23.2 0.0 0.00011 22.0 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EAQ84674.1 - 0.00046 20.9 0.2 0.0011 19.6 0.0 1.5 1 1 1 2 2 2 1 Alpha/beta hydrolase family Thioesterase PF00975.20 EAQ84674.1 - 0.00067 19.8 0.0 0.0012 19.0 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Hydrolase_4 PF12146.8 EAQ84674.1 - 0.022 14.0 0.0 0.041 13.1 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF915 PF06028.11 EAQ84674.1 - 0.028 13.7 0.0 0.059 12.7 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Lipase_2 PF01674.18 EAQ84674.1 - 0.039 13.5 0.0 0.13 11.7 0.0 1.7 2 0 0 2 2 2 0 Lipase (class 2) Ser_hydrolase PF06821.13 EAQ84674.1 - 0.057 13.3 0.0 0.094 12.6 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase DUF900 PF05990.12 EAQ84674.1 - 0.059 12.9 0.0 0.084 12.4 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) DUF4965 PF16335.5 EAQ84675.1 - 4.6e-74 247.8 0.3 8.2e-74 247.0 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) DUF5127 PF17168.4 EAQ84675.1 - 2e-72 243.7 8.5 1.4e-71 240.9 8.5 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF5127) DUF1793 PF08760.11 EAQ84675.1 - 5.5e-64 215.6 0.2 1.4e-63 214.3 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) DUF4964 PF16334.5 EAQ84675.1 - 1.8e-07 30.6 0.1 7e-07 28.7 0.1 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4964) Endosulfine PF04667.17 EAQ84676.1 - 2.3e-28 98.1 2.1 1.8e-27 95.3 0.0 2.2 2 0 0 2 2 2 1 cAMP-regulated phosphoprotein/endosulfine conserved region DUF5349 PF17298.2 EAQ84676.1 - 0.49 10.1 4.2 0.5 10.1 0.0 2.0 1 1 1 2 2 2 0 Family of unknown function (DUF5349) UPF0160 PF03690.13 EAQ84677.1 - 2.4e-135 451.3 0.0 2.7e-135 451.1 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) Ino80_Iec3 PF14612.6 EAQ84678.1 - 9.1e-56 190.2 3.0 1.4e-27 97.9 1.4 2.1 1 1 1 2 2 2 2 IEC3 subunit of the Ino80 complex, chromatin re-modelling Iso_dh PF00180.20 EAQ84679.1 - 3.3e-70 237.0 0.0 3.8e-70 236.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase zf-C2H2_aberr PF17017.5 EAQ84680.1 - 0.0028 17.8 3.2 0.0045 17.2 3.2 1.3 1 0 0 1 1 1 1 Aberrant zinc-finger FOXP-CC PF16159.5 EAQ84680.1 - 0.19 12.4 7.5 7 7.4 0.1 3.6 3 1 1 4 4 4 0 FOXP coiled-coil domain Not3 PF04065.15 EAQ84681.1 - 7.9e-92 306.9 21.0 1.4e-91 306.1 21.0 1.4 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 EAQ84681.1 - 6.4e-38 129.8 4.3 1.6e-37 128.6 4.3 1.6 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family DUF2373 PF10180.9 EAQ84681.1 - 0.0018 18.0 0.1 0.0041 16.9 0.1 1.6 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) Syntaxin_2 PF14523.6 EAQ84681.1 - 0.0051 17.2 4.7 0.0051 17.2 4.7 2.2 2 0 0 2 2 2 1 Syntaxin-like protein DUF1192 PF06698.11 EAQ84681.1 - 0.011 15.8 1.2 0.011 15.8 1.2 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1192) ABC_tran_CTD PF16326.5 EAQ84681.1 - 0.015 15.5 4.7 0.015 15.5 4.7 3.5 2 1 2 4 4 2 0 ABC transporter C-terminal domain HR1 PF02185.16 EAQ84681.1 - 0.03 14.4 1.8 0.03 14.4 1.8 3.0 4 0 0 4 4 3 0 Hr1 repeat Cep57_MT_bd PF06657.13 EAQ84681.1 - 0.046 14.2 8.1 0.4 11.2 2.6 3.0 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 LPP PF04728.13 EAQ84681.1 - 0.15 12.5 3.2 0.49 10.8 0.0 3.2 3 1 1 4 4 3 0 Lipoprotein leucine-zipper Poty_PP PF08440.10 EAQ84681.1 - 0.2 10.7 2.2 0.36 9.9 2.2 1.3 1 0 0 1 1 1 0 Potyviridae polyprotein Snapin_Pallidin PF14712.6 EAQ84681.1 - 0.39 11.2 7.9 2 8.9 0.2 2.6 2 0 0 2 2 2 0 Snapin/Pallidin DUF5473 PF17567.2 EAQ84681.1 - 0.42 10.9 8.1 0.12 12.7 1.9 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5473) Sec5 PF15469.6 EAQ84681.1 - 0.78 9.5 7.3 0.21 11.4 1.8 2.3 2 0 0 2 2 2 0 Exocyst complex component Sec5 4HB_MCP_1 PF12729.7 EAQ84681.1 - 0.99 8.9 12.5 0.5 9.9 7.8 2.2 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction Fzo_mitofusin PF04799.13 EAQ84681.1 - 1.2 8.7 10.6 8.5 5.9 5.0 2.5 2 0 0 2 2 2 0 fzo-like conserved region DUF4140 PF13600.6 EAQ84681.1 - 2.6 8.6 7.7 22 5.6 0.2 3.1 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) DUF948 PF06103.11 EAQ84681.1 - 4.5 7.6 4.2 46 4.4 0.7 2.6 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) CorA PF01544.18 EAQ84681.1 - 5 6.3 7.6 1.2 8.4 1.2 2.2 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein Swi5 PF07061.11 EAQ84681.1 - 6.6 6.9 12.5 13 6.0 0.4 2.9 2 1 0 2 2 2 0 Swi5 Tyr_Deacylase PF02580.16 EAQ84682.1 - 1.3e-36 126.3 0.0 1.4e-36 126.2 0.0 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Pro_isomerase PF00160.21 EAQ84683.1 - 6e-47 159.8 0.3 9.6e-47 159.2 0.3 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_2 PF07719.17 EAQ84683.1 - 2.9e-08 33.2 2.3 2.3e-05 24.2 0.3 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 EAQ84683.1 - 3e-06 26.8 1.9 1.2e-05 24.9 0.1 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 EAQ84683.1 - 7.9e-05 22.6 0.1 0.00023 21.1 0.1 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.6 EAQ84683.1 - 0.00096 18.8 4.8 0.34 10.6 0.7 3.2 2 1 1 3 3 3 2 TPR repeat TPR_9 PF13371.6 EAQ84683.1 - 0.0024 18.0 1.0 0.011 15.9 0.4 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 EAQ84683.1 - 0.0028 18.3 1.8 0.0081 16.9 0.7 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 EAQ84683.1 - 0.018 15.6 0.5 0.098 13.3 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 EAQ84683.1 - 0.052 14.2 4.0 1.7 9.4 0.3 2.6 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 EAQ84683.1 - 0.071 13.4 0.3 1.2 9.5 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 EAQ84683.1 - 0.096 13.2 3.4 0.87 10.1 0.9 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat RasGAP PF00616.19 EAQ84684.1 - 3.7e-31 108.5 0.0 2.1e-21 76.6 0.0 3.4 3 1 1 4 4 4 2 GTPase-activator protein for Ras-like GTPase RSB_motif PF16294.5 EAQ84684.1 - 0.41 10.9 10.8 20 5.5 9.9 2.4 2 0 0 2 2 2 0 RNSP1-SAP18 binding (RSB) motif SNF2_N PF00176.23 EAQ84686.1 - 2.9e-16 59.2 0.0 1.4e-15 56.9 0.0 1.9 2 0 0 2 2 2 1 SNF2 family N-terminal domain ResIII PF04851.15 EAQ84686.1 - 0.013 15.5 0.0 0.026 14.5 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.6 EAQ84686.1 - 0.014 15.6 0.2 0.33 11.1 0.4 2.6 2 1 0 2 2 2 0 Helicase C-terminal domain zf-RING_5 PF14634.6 EAQ84686.1 - 0.048 13.6 15.5 0.0085 16.0 4.2 2.6 2 0 0 2 2 2 0 zinc-RING finger domain DNA_methylase PF00145.17 EAQ84686.1 - 0.062 12.6 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 C-5 cytosine-specific DNA methylase FYVE PF01363.21 EAQ84686.1 - 4.1 7.6 6.6 4.3 7.5 0.3 2.6 2 0 0 2 2 2 0 FYVE zinc finger Ureidogly_lyase PF04115.12 EAQ84687.1 - 1.2e-36 126.3 0.0 1.5e-36 126.0 0.0 1.1 1 0 0 1 1 1 1 Ureidoglycolate lyase MFS_1 PF07690.16 EAQ84690.1 - 0.0013 17.8 0.7 0.0014 17.6 0.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily bZIP_1 PF00170.21 EAQ84691.1 - 0.00073 19.6 16.0 0.0022 18.0 16.0 1.7 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EAQ84691.1 - 0.0044 17.1 15.9 0.037 14.1 8.7 2.2 2 0 0 2 2 2 2 Basic region leucine zipper DUF3435 PF11917.8 EAQ84691.1 - 0.024 13.6 3.6 0.031 13.2 3.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) HALZ PF02183.18 EAQ84691.1 - 0.04 14.2 2.5 0.85 9.9 0.5 2.4 2 0 0 2 2 2 0 Homeobox associated leucine zipper Speriolin_N PF15058.6 EAQ84691.1 - 0.058 13.5 0.2 0.058 13.5 0.2 1.6 2 0 0 2 2 2 0 Speriolin N terminus YabA PF06156.13 EAQ84691.1 - 1.4 9.6 5.8 0.86 10.3 2.3 2.1 1 1 1 2 2 2 0 Initiation control protein YabA DUF4570 PF15134.6 EAQ84691.1 - 1.7 8.7 8.1 2.7 8.1 7.5 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4570) TSC22 PF01166.18 EAQ84691.1 - 2.3 8.6 6.6 0.54 10.6 2.0 2.1 1 1 1 2 2 2 0 TSC-22/dip/bun family PseudoU_synth_2 PF00849.22 EAQ84693.1 - 3.3e-28 98.8 0.0 4.9e-28 98.2 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase Auto_anti-p27 PF06677.12 EAQ84693.1 - 0.013 15.7 0.1 0.027 14.6 0.1 1.4 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) S4 PF01479.25 EAQ84693.1 - 0.051 13.3 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 S4 domain Ub-Mut7C PF14451.6 EAQ84693.1 - 0.076 12.9 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Mut7-C ubiquitin RT_RNaseH PF17917.1 EAQ84694.1 - 1.5e-33 115.2 0.0 4.9e-33 113.6 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 EAQ84694.1 - 3e-28 97.8 0.0 8.9e-28 96.3 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 EAQ84694.1 - 1.6e-24 86.6 0.0 3.9e-24 85.4 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HAP1_N PF04849.13 EAQ84694.1 - 4.9e-05 22.7 1.8 0.00011 21.5 1.8 1.5 1 0 0 1 1 1 1 HAP1 N-terminal conserved region DUF4939 PF16297.5 EAQ84694.1 - 0.00022 21.1 0.0 0.00054 19.8 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) zf-CCHC PF00098.23 EAQ84694.1 - 0.0011 19.0 3.9 0.002 18.1 3.9 1.5 1 0 0 1 1 1 1 Zinc knuckle Asp_protease_2 PF13650.6 EAQ84694.1 - 0.002 18.8 0.0 0.019 15.6 0.0 2.4 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 EAQ84694.1 - 0.042 14.4 0.0 0.15 12.7 0.0 1.9 2 0 0 2 2 1 0 gag-polyprotein putative aspartyl protease Atg14 PF10186.9 EAQ84694.1 - 0.14 11.3 0.5 0.4 9.7 0.5 1.8 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 IFT57 PF10498.9 EAQ84694.1 - 0.15 11.0 9.4 0.19 10.7 7.1 2.1 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 RVP_2 PF08284.11 EAQ84694.1 - 0.16 11.8 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease CENP-F_leu_zip PF10473.9 EAQ84694.1 - 0.3 11.1 6.6 1.6 8.7 6.0 2.6 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Csm1_N PF18504.1 EAQ84694.1 - 6.6 7.2 9.9 6.4 7.2 5.0 3.2 3 0 0 3 3 3 0 Csm1 N-terminal domain YCII PF03795.14 EAQ84696.1 - 0.013 15.9 0.1 0.023 15.1 0.1 1.3 1 0 0 1 1 1 0 YCII-related domain DUF1043 PF06295.12 EAQ84696.1 - 0.015 15.3 0.9 0.029 14.4 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DUF724 PF05266.14 EAQ84696.1 - 0.02 14.7 1.1 0.024 14.5 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Prefoldin PF02996.17 EAQ84696.1 - 0.03 14.2 0.1 0.049 13.6 0.1 1.3 1 0 0 1 1 1 0 Prefoldin subunit DUF2852 PF11014.8 EAQ84696.1 - 0.57 10.3 5.8 0.51 10.5 4.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2852) HTH_Tnp_Tc5 PF03221.16 EAQ84697.1 - 0.0026 17.8 0.0 0.005 16.8 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain MULE PF10551.9 EAQ84699.1 - 3.8e-27 94.6 0.4 8.1e-27 93.5 0.1 1.8 2 0 0 2 2 2 1 MULE transposase domain DDE_1 PF03184.19 EAQ84700.1 - 2.4e-29 102.2 0.1 6.3e-29 100.8 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 EAQ84700.1 - 1.3e-22 79.8 0.7 4e-22 78.2 0.2 2.2 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 EAQ84700.1 - 4.6e-14 52.4 0.2 3.2e-05 23.7 0.0 3.8 3 0 0 3 3 3 2 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 EAQ84700.1 - 2.2e-07 30.8 0.0 8.5e-07 28.9 0.0 2.1 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.16 EAQ84700.1 - 4.1e-07 29.6 0.0 8.6e-07 28.6 0.0 1.6 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_33 PF13592.6 EAQ84700.1 - 0.00014 21.4 4.8 0.00021 20.9 0.0 3.6 4 0 0 4 4 4 1 Winged helix-turn helix HTH_32 PF13565.6 EAQ84700.1 - 0.00038 21.0 0.1 0.00038 21.0 0.1 6.4 6 1 0 6 6 6 1 Homeodomain-like domain ZapB PF06005.12 EAQ84700.1 - 2.1 8.8 5.6 0.26 11.7 0.4 2.2 2 0 0 2 2 2 0 Cell division protein ZapB UvrD_C_2 PF13538.6 EAQ84701.1 - 2.5e-06 27.2 0.1 6.4e-06 25.9 0.1 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.14 EAQ84701.1 - 0.00015 19.9 0.0 0.00017 19.7 0.0 1.0 1 0 0 1 1 1 1 Helicase Viral_helicase1 PF01443.18 EAQ84701.1 - 0.13 12.0 0.0 0.16 11.7 0.0 1.1 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Helitron_like_N PF14214.6 EAQ84704.1 - 2.6e-25 89.8 0.5 1.7e-24 87.1 0.5 2.2 1 1 0 1 1 1 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.14 EAQ84704.1 - 7.8e-25 87.8 0.0 1.4e-18 67.2 0.0 2.3 2 0 0 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 EAQ84704.1 - 2.5e-06 27.3 0.0 7.8e-06 25.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain Herpes_Helicase PF02689.14 EAQ84704.1 - 0.011 13.7 0.0 0.018 13.0 0.0 1.2 1 0 0 1 1 1 0 Helicase AZUL PF16558.5 EAQ84704.1 - 0.089 13.0 0.4 0.22 11.8 0.4 1.6 1 0 0 1 1 1 0 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A UvrD_C_2 PF13538.6 EAQ84704.1 - 0.095 12.5 0.1 0.31 10.9 0.0 2.0 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain FAT PF02259.23 EAQ84706.1 - 1.4e-89 300.8 0.3 4.5e-89 299.0 0.3 1.9 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.27 EAQ84706.1 - 8.9e-74 248.4 0.1 1.5e-73 247.7 0.1 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.8 EAQ84706.1 - 1.9e-67 226.2 4.6 9.7e-65 217.4 0.1 4.7 5 0 0 5 5 5 2 Domain of unknown function (DUF3385) FRB_dom PF08771.11 EAQ84706.1 - 2e-44 150.0 0.4 1.3e-43 147.5 0.0 2.8 2 0 0 2 2 1 1 FKBP12-rapamycin binding domain HEAT PF02985.22 EAQ84706.1 - 1.7e-17 62.0 8.7 0.0017 18.4 0.0 9.5 10 0 0 10 10 8 4 HEAT repeat FATC PF02260.20 EAQ84706.1 - 1.7e-14 53.3 1.1 3.5e-14 52.3 0.2 2.1 2 0 0 2 2 1 1 FATC domain HEAT_2 PF13646.6 EAQ84706.1 - 1e-11 45.1 6.2 0.0046 17.3 0.2 6.1 5 0 0 5 5 5 2 HEAT repeats Cnd1 PF12717.7 EAQ84706.1 - 1.5e-08 34.8 4.7 0.063 13.3 0.0 6.1 4 1 3 7 7 6 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 EAQ84706.1 - 2.7e-05 24.6 17.8 0.13 12.8 0.1 9.4 10 1 1 11 11 9 1 HEAT-like repeat Adaptin_N PF01602.20 EAQ84706.1 - 0.00024 19.8 4.4 0.0039 15.8 0.3 3.4 2 1 1 3 3 3 1 Adaptin N terminal region CLASP_N PF12348.8 EAQ84706.1 - 0.0011 18.5 5.7 3.6 7.1 0.0 5.3 4 1 1 5 5 5 2 CLASP N terminal DUF3730 PF12530.8 EAQ84706.1 - 0.003 17.1 1.6 4 6.9 0.0 4.4 4 1 1 5 5 5 1 Protein of unknown function (DUF3730) UME PF08064.13 EAQ84706.1 - 0.0051 16.7 4.0 22 5.0 0.0 6.2 7 0 0 7 7 6 0 UME (NUC010) domain FANCI_S2 PF14676.6 EAQ84706.1 - 0.0098 16.2 0.7 1.8 8.9 0.1 3.9 4 0 0 4 4 4 1 FANCI solenoid 2 RIX1 PF08167.12 EAQ84706.1 - 0.046 13.5 0.0 5.3 6.7 0.0 3.5 2 0 0 2 2 2 0 rRNA processing/ribosome biogenesis GAT PF03127.14 EAQ84706.1 - 0.11 12.8 0.3 6.4 7.2 0.0 3.9 4 0 0 4 4 3 0 GAT domain DUF615 PF04751.14 EAQ84706.1 - 4.2 7.3 8.8 8.1 6.4 0.0 4.3 5 0 0 5 5 5 0 Protein of unknown function (DUF615) Rtf2 PF04641.12 EAQ84707.1 - 1.8e-39 135.7 1.6 6.6e-30 104.3 2.0 2.1 1 1 1 2 2 2 2 Rtf2 RING-finger zf-RING_5 PF14634.6 EAQ84707.1 - 9e-05 22.4 0.1 0.00014 21.8 0.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EAQ84707.1 - 0.00087 19.1 0.2 0.0022 17.8 0.3 1.6 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 EAQ84707.1 - 0.00096 19.1 0.0 0.003 17.5 0.1 1.8 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EAQ84707.1 - 0.0028 17.4 0.3 0.0047 16.7 0.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EAQ84707.1 - 0.0032 17.8 0.1 0.0058 16.9 0.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 EAQ84707.1 - 0.036 13.8 0.4 0.33 10.8 0.0 2.2 2 0 0 2 2 2 0 RING-like zinc finger zf-C3HC4_3 PF13920.6 EAQ84707.1 - 0.13 12.2 0.1 0.24 11.3 0.1 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) UPF0547 PF10571.9 EAQ84707.1 - 1 9.5 3.8 7 6.8 0.8 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 PRKCSH-like PF12999.7 EAQ84708.1 - 1.2e-38 132.6 8.3 1.3e-22 80.4 1.4 3.1 3 1 0 3 3 3 2 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 EAQ84708.1 - 7.6e-24 84.2 3.3 1.5e-23 83.2 0.4 2.3 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein ATG27 PF09451.10 EAQ84708.1 - 0.00044 20.2 0.4 0.00044 20.2 0.4 2.1 2 0 0 2 2 2 1 Autophagy-related protein 27 NuA4 PF09340.10 EAQ84708.1 - 0.011 15.6 0.2 0.011 15.6 0.2 3.0 3 1 1 4 4 4 0 Histone acetyltransferase subunit NuA4 NPV_P10 PF05531.12 EAQ84708.1 - 0.029 14.8 6.4 0.083 13.4 0.5 2.9 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF773 PF05600.12 EAQ84708.1 - 0.035 12.8 5.6 0.026 13.3 3.8 1.4 1 1 0 1 1 1 0 CDK5 regulatory subunit-associated protein 3 PspB PF06667.12 EAQ84708.1 - 0.15 12.2 0.2 0.15 12.2 0.2 2.6 2 0 0 2 2 2 0 Phage shock protein B Prefoldin_2 PF01920.20 EAQ84708.1 - 0.15 12.1 18.4 3.9 7.5 0.1 3.9 3 1 0 3 3 3 0 Prefoldin subunit Fib_alpha PF08702.10 EAQ84708.1 - 0.18 12.0 3.4 3.2 7.9 0.0 2.5 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Syntaxin-6_N PF09177.11 EAQ84708.1 - 0.3 11.6 10.8 6.2 7.4 0.1 3.3 3 0 0 3 3 3 0 Syntaxin 6, N-terminal Mod_r PF07200.13 EAQ84708.1 - 0.32 11.1 13.2 0.17 12.0 0.4 2.7 3 0 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein Sec34 PF04136.15 EAQ84708.1 - 0.64 9.9 4.6 5.6 6.8 0.0 2.8 3 0 0 3 3 3 0 Sec34-like family Apt1 PF10351.9 EAQ84708.1 - 0.82 8.4 11.2 0.14 10.9 0.1 2.2 2 0 0 2 2 2 0 Golgi-body localisation protein domain Laminin_II PF06009.12 EAQ84708.1 - 1.1 9.3 7.5 0.18 11.8 3.5 1.8 2 0 0 2 2 2 0 Laminin Domain II DUF4200 PF13863.6 EAQ84708.1 - 1.2 9.6 20.5 19 5.6 14.1 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4200) Jnk-SapK_ap_N PF09744.9 EAQ84708.1 - 1.2 9.4 17.8 7.6 6.7 11.3 3.1 3 0 0 3 3 3 0 JNK_SAPK-associated protein-1 BLOC1_2 PF10046.9 EAQ84708.1 - 1.5 9.2 10.0 5.1 7.5 1.1 2.8 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4407 PF14362.6 EAQ84708.1 - 1.6 8.0 16.8 0.21 10.9 3.8 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) Filament PF00038.21 EAQ84708.1 - 4 6.9 21.6 2 7.9 0.4 2.7 3 0 0 3 3 3 0 Intermediate filament protein TPR_MLP1_2 PF07926.12 EAQ84708.1 - 4.4 7.4 20.9 8 6.5 0.2 3.7 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein Ldl_recept_a PF00057.18 EAQ84708.1 - 5.8 7.2 13.0 0.78 10.0 1.8 2.8 2 0 0 2 2 2 0 Low-density lipoprotein receptor domain class A JIP_LZII PF16471.5 EAQ84708.1 - 7.1 6.9 20.0 6.6 7.0 0.0 4.2 3 1 0 4 4 4 0 JNK-interacting protein leucine zipper II GCIP PF13324.6 EAQ84709.1 - 3e-21 76.2 0.0 6.7e-21 75.1 0.0 1.5 1 1 0 1 1 1 1 Grap2 and cyclin-D-interacting DUF883 PF05957.13 EAQ84709.1 - 0.42 11.3 2.6 12 6.5 0.1 3.2 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF883) Uso1_p115_C PF04871.13 EAQ84709.1 - 1.6 9.1 8.0 6.1 7.2 8.0 2.0 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region DbpA PF03880.15 EAQ84711.1 - 0.041 13.9 0.0 0.079 13.0 0.0 1.5 1 0 0 1 1 1 0 DbpA RNA binding domain Methyltransf_23 PF13489.6 EAQ84712.1 - 1.3e-09 38.1 0.0 1.9e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EAQ84712.1 - 3.5e-05 24.5 0.0 0.00021 22.0 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAQ84712.1 - 0.00011 22.9 0.0 0.00023 21.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EAQ84712.1 - 0.02 15.6 0.0 0.071 13.8 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Cyto_heme_lyase PF01265.17 EAQ84713.1 - 2.1e-121 405.0 0.3 2.4e-121 404.8 0.3 1.0 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase ABC1 PF03109.16 EAQ84714.1 - 3e-25 88.7 0.0 2.5e-15 56.7 0.0 2.4 1 1 0 2 2 2 2 ABC1 family APH PF01636.23 EAQ84714.1 - 0.0061 16.5 0.2 0.047 13.6 0.2 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 EAQ84714.1 - 0.15 11.7 0.0 1.9 8.1 0.0 2.2 2 0 0 2 2 2 0 RIO1 family Glyco_hydro_71 PF03659.14 EAQ84715.1 - 1.6e-37 129.2 5.2 3.6e-37 128.1 5.2 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 71 RhgB_N PF09284.10 EAQ84716.1 - 3e-107 357.8 3.0 4.4e-107 357.3 3.0 1.3 1 0 0 1 1 1 1 Rhamnogalacturonan lyase B, N-terminal CBM-like PF14683.6 EAQ84716.1 - 7.2e-40 136.6 0.0 1.7e-39 135.3 0.0 1.6 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.6 EAQ84716.1 - 6.4e-23 80.3 5.3 2.3e-22 78.5 5.3 2.0 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.6 EAQ84716.1 - 0.00017 21.8 3.5 0.00017 21.8 3.5 3.1 4 0 0 4 4 4 1 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 EAQ84716.1 - 0.024 14.6 1.0 0.024 14.6 1.0 2.3 2 0 0 2 2 2 0 CarboxypepD_reg-like domain DUF2012 PF09430.10 EAQ84716.1 - 0.16 12.1 0.0 0.35 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2012) Peptidase_M28 PF04389.17 EAQ84717.1 - 1.1e-39 136.3 0.0 1.6e-39 135.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 EAQ84717.1 - 4.9e-10 39.5 0.0 9.6e-10 38.5 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 EAQ84717.1 - 0.049 12.7 0.0 0.41 9.6 0.0 2.1 2 0 0 2 2 2 0 M42 glutamyl aminopeptidase Sugar_tr PF00083.24 EAQ84718.1 - 1.7e-44 152.4 8.8 7e-32 110.9 0.4 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EAQ84718.1 - 3.9e-14 52.3 20.6 3.4e-07 29.5 6.0 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Arch_fla_DE PF04659.13 EAQ84718.1 - 0.12 12.2 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Archaeal flagella protein CDH-cyt PF16010.5 EAQ84719.1 - 1.5e-50 171.4 0.1 1.8e-50 171.2 0.1 1.0 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase Aldo_ket_red PF00248.21 EAQ84720.1 - 1.6e-29 103.1 0.0 6.2e-14 51.9 0.0 2.7 1 1 1 2 2 2 2 Aldo/keto reductase family Peptidase_S49_N PF08496.10 EAQ84721.1 - 0.59 10.2 3.3 1.5 8.9 3.3 1.6 1 0 0 1 1 1 0 Peptidase family S49 N-terminal FYVE PF01363.21 EAQ84721.1 - 0.84 9.8 4.5 1.8 8.8 4.5 1.5 1 0 0 1 1 1 0 FYVE zinc finger ABC_tran PF00005.27 EAQ84724.1 - 3.6e-18 66.4 0.0 5.5e-18 65.8 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 EAQ84724.1 - 2.8e-09 36.7 0.3 4.1e-09 36.2 0.3 1.2 1 0 0 1 1 1 1 ABC-2 type transporter AAA_21 PF13304.6 EAQ84724.1 - 1.1e-05 25.5 0.3 0.063 13.1 0.0 2.4 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EAQ84724.1 - 2.7e-05 24.6 0.1 6.1e-05 23.5 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 EAQ84724.1 - 7.7e-05 22.3 0.2 0.00014 21.5 0.2 1.5 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EAQ84724.1 - 9.2e-05 22.4 0.1 0.00017 21.5 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_18 PF13238.6 EAQ84724.1 - 0.00059 20.4 0.0 0.001 19.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EAQ84724.1 - 0.0035 17.0 0.1 0.0078 15.9 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 EAQ84724.1 - 0.0045 16.4 0.0 0.3 10.5 0.0 2.2 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_33 PF13671.6 EAQ84724.1 - 0.0099 16.1 0.0 0.021 15.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EAQ84724.1 - 0.017 15.4 0.2 0.061 13.6 0.1 1.9 1 1 0 2 2 2 0 AAA domain AAA_23 PF13476.6 EAQ84724.1 - 0.017 15.6 0.0 0.038 14.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 EAQ84724.1 - 0.018 14.6 0.1 0.031 13.9 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Bac_surface_Ag PF01103.23 EAQ84725.1 - 5.4e-43 147.7 0.1 6.9e-43 147.4 0.1 1.1 1 0 0 1 1 1 1 Surface antigen UQ_con PF00179.26 EAQ84726.1 - 2.9e-19 69.1 0.1 4.1e-19 68.6 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Mannosidase_ig PF17786.1 EAQ84727.1 - 3.1e-17 63.0 0.3 1.5e-16 60.8 0.2 2.3 2 0 0 2 2 2 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 EAQ84727.1 - 1.4e-05 25.7 0.1 8.8e-05 23.1 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_C PF02836.17 EAQ84727.1 - 0.00085 18.5 0.0 0.0019 17.3 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Aldo_ket_red PF00248.21 EAQ84728.1 - 1.8e-69 234.2 0.0 2.1e-69 233.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family zf-RVT PF13966.6 EAQ84729.1 - 0.036 14.8 0.0 0.16 12.7 0.0 1.8 2 0 0 2 2 2 0 zinc-binding in reverse transcriptase ABC_membrane PF00664.23 EAQ84730.1 - 1.4e-72 244.6 36.6 3.4e-45 154.8 16.5 3.1 2 1 1 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.27 EAQ84730.1 - 3.1e-29 102.2 0.0 3.2e-27 95.7 0.0 2.6 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 EAQ84730.1 - 5.7e-07 29.2 0.0 0.00082 18.9 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EAQ84730.1 - 0.00073 19.2 0.0 0.002 17.8 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 EAQ84730.1 - 0.011 16.0 0.1 0.15 12.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 EAQ84730.1 - 0.029 14.3 0.0 0.059 13.3 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase ATPase PF06745.13 EAQ84730.1 - 0.035 13.4 0.1 0.065 12.6 0.1 1.4 1 0 0 1 1 1 0 KaiC AAA_23 PF13476.6 EAQ84730.1 - 0.059 13.9 0.0 0.11 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAQ84730.1 - 0.15 11.6 1.1 0.23 11.0 0.1 1.8 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EAQ84730.1 - 0.26 11.6 2.7 0.63 10.4 0.0 2.8 3 1 1 4 4 4 0 AAA ATPase domain FSH1 PF03959.13 EAQ84731.1 - 3.4e-20 72.6 0.0 1.1e-19 70.9 0.0 1.6 1 1 0 1 1 1 1 Serine hydrolase (FSH1) PE-PPE PF08237.11 EAQ84731.1 - 0.029 13.9 0.0 0.041 13.4 0.0 1.2 1 0 0 1 1 1 0 PE-PPE domain KR PF08659.10 EAQ84732.1 - 5e-62 209.0 0.3 2e-60 203.8 0.2 3.0 3 0 0 3 3 3 1 KR domain Acyl_transf_1 PF00698.21 EAQ84732.1 - 1.6e-50 172.5 0.0 2.7e-50 171.7 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain ketoacyl-synt PF00109.26 EAQ84732.1 - 1.7e-50 172.0 0.0 2e-31 109.5 0.0 2.7 1 1 1 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.6 EAQ84732.1 - 3.7e-46 157.7 0.0 8e-46 156.6 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 EAQ84732.1 - 3.4e-22 78.7 0.0 6e-20 71.4 0.0 3.1 1 1 1 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 EAQ84732.1 - 9.7e-20 71.1 0.0 3.2e-19 69.5 0.0 1.9 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 EAQ84732.1 - 1.1e-15 57.6 0.1 7.4e-15 54.9 0.2 2.4 2 0 0 2 2 2 1 short chain dehydrogenase ADH_zinc_N_2 PF13602.6 EAQ84732.1 - 9.7e-15 55.8 0.0 3.9e-14 53.8 0.0 2.1 2 0 0 2 2 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EAQ84732.1 - 3.8e-13 49.5 0.6 1.4e-12 47.7 0.0 2.3 2 0 0 2 2 2 1 Zinc-binding dehydrogenase PP-binding PF00550.25 EAQ84732.1 - 9.7e-07 29.1 0.2 4.4e-06 27.0 0.2 2.2 2 0 0 2 2 2 1 Phosphopantetheine attachment site ADH_N PF08240.12 EAQ84732.1 - 0.0001 22.2 0.0 0.00033 20.5 0.0 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PALP PF00291.25 EAQ84732.1 - 0.0029 17.0 1.2 0.29 10.5 0.1 2.6 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme NmrA PF05368.13 EAQ84732.1 - 0.061 12.9 3.1 0.038 13.5 0.2 2.0 2 0 0 2 2 2 0 NmrA-like family GDP_Man_Dehyd PF16363.5 EAQ84732.1 - 0.095 12.1 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Sugar_tr PF00083.24 EAQ84733.1 - 7.1e-63 213.0 14.6 7.1e-45 153.7 0.1 3.0 1 1 2 3 3 3 3 Sugar (and other) transporter HOASN PF14515.6 EAQ84733.1 - 0.11 12.8 0.0 0.24 11.8 0.0 1.4 1 0 0 1 1 1 0 Haem-oxygenase-associated N-terminal helices PAP_assoc PF03828.19 EAQ84734.1 - 7.3e-15 54.9 0.1 1.5e-14 53.9 0.1 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 EAQ84734.1 - 7.3e-06 26.2 0.0 1.7e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Actin PF00022.19 EAQ84735.1 - 7.3e-103 344.3 0.0 6.3e-102 341.2 0.0 1.9 1 1 0 1 1 1 1 Actin Ldh_2 PF02615.14 EAQ84736.1 - 3.3e-126 421.0 0.8 3.7e-126 420.8 0.8 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase Sugar_tr PF00083.24 EAQ84737.1 - 7.4e-80 269.0 20.7 8.8e-80 268.8 20.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EAQ84737.1 - 4.2e-16 58.8 58.3 2.6e-14 52.9 26.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Peptidase_A4 PF01828.17 EAQ84738.1 - 1.2e-44 152.3 9.9 1.6e-44 151.9 9.9 1.1 1 0 0 1 1 1 1 Peptidase A4 family fn3 PF00041.21 EAQ84738.1 - 0.019 15.3 0.1 0.041 14.2 0.1 1.5 1 0 0 1 1 1 0 Fibronectin type III domain CCT PF06203.14 EAQ84739.1 - 0.044 13.8 0.0 0.089 12.9 0.0 1.4 1 0 0 1 1 1 0 CCT motif Imm64 PF15600.6 EAQ84739.1 - 0.12 12.1 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 Immunity protein 64 UFD1 PF03152.14 EAQ84740.1 - 3.5e-27 95.0 0.0 5.2e-14 52.1 0.0 3.6 3 1 0 3 3 3 2 Ubiquitin fusion degradation protein UFD1 AZUL PF16558.5 EAQ84740.1 - 8.7e-07 29.1 0.9 2.7e-06 27.5 0.0 2.3 2 0 0 2 2 2 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A DDE_3 PF13358.6 EAQ84741.1 - 1.4e-13 50.8 0.0 2.5e-13 50.0 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 EAQ84741.1 - 1e-07 32.1 0.0 2.4e-07 30.9 0.0 1.7 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 EAQ84741.1 - 0.0032 18.0 4.9 0.048 14.3 0.0 3.7 2 2 2 4 4 4 1 Homeodomain-like domain HTH_23 PF13384.6 EAQ84741.1 - 0.008 16.0 0.0 0.022 14.5 0.0 1.8 1 0 0 1 1 1 1 Homeodomain-like domain TAL_effector PF03377.13 EAQ84741.1 - 0.065 13.6 0.1 0.45 10.9 0.0 2.3 2 0 0 2 2 2 0 TAL effector repeat MFS_1 PF07690.16 EAQ84742.1 - 5.1e-51 173.7 37.0 5.9e-51 173.5 37.0 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EAQ84742.1 - 6.7e-16 58.2 4.7 6.7e-16 58.2 4.7 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_3 PF05977.13 EAQ84742.1 - 0.0069 14.8 5.7 0.0084 14.6 5.0 1.4 1 1 0 1 1 1 1 Transmembrane secretion effector OATP PF03137.20 EAQ84742.1 - 4.2 5.5 16.3 1 7.6 9.8 2.8 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Abhydrolase_1 PF00561.20 EAQ84744.1 - 1e-17 64.7 0.0 1.3e-17 64.3 0.0 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EAQ84744.1 - 9.1e-13 49.3 7.8 1.2e-12 49.0 7.8 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EAQ84744.1 - 0.0004 19.7 0.0 0.00068 19.0 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 EHN PF06441.12 EAQ84744.1 - 0.06 13.7 0.1 0.17 12.2 0.1 1.8 1 0 0 1 1 1 0 Epoxide hydrolase N terminus Ank_2 PF12796.7 EAQ84751.1 - 3.5e-58 194.1 0.0 2.6e-12 47.1 0.0 7.6 5 2 3 9 9 9 7 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAQ84751.1 - 5e-46 154.2 4.5 5.2e-06 26.6 0.0 9.7 5 3 5 10 10 10 10 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAQ84751.1 - 3.2e-39 132.8 2.1 4.8e-07 30.2 0.0 10.5 5 4 6 11 11 11 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAQ84751.1 - 1.3e-38 126.6 1.9 0.0047 17.3 0.0 13.2 12 0 0 12 12 12 8 Ankyrin repeat Ank PF00023.30 EAQ84751.1 - 1.5e-37 126.4 0.0 0.00042 20.6 0.0 12.3 11 1 0 11 11 11 7 Ankyrin repeat Glyco_hydro_3 PF00933.21 EAQ84751.1 - 3.9e-37 128.3 0.0 1.2e-36 126.7 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 N terminal domain PNP_UDP_1 PF01048.20 EAQ84751.1 - 6.6e-15 55.0 0.2 1.2e-14 54.2 0.2 1.4 1 0 0 1 1 1 1 Phosphorylase superfamily NACHT PF05729.12 EAQ84751.1 - 2.7e-08 33.9 1.2 3.3e-08 33.6 0.1 1.7 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 EAQ84751.1 - 3.5e-05 24.2 0.3 0.00017 22.0 0.1 2.3 2 0 0 2 2 2 1 AAA ATPase domain Glyco_hydro_3_C PF01915.22 EAQ84751.1 - 0.029 14.3 0.0 0.055 13.4 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain Viral_helicase1 PF01443.18 EAQ84751.1 - 0.096 12.4 0.0 0.35 10.6 0.0 1.9 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.22 EAQ84751.1 - 0.12 12.8 0.0 0.27 11.6 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Dabb PF07876.12 EAQ84754.1 - 0.0015 19.1 0.0 0.0026 18.3 0.0 1.6 1 1 0 1 1 1 1 Stress responsive A/B Barrel Domain SARAF PF06682.12 EAQ84757.1 - 0.045 13.4 2.5 0.047 13.3 2.5 1.1 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Pex24p PF06398.11 EAQ84758.1 - 7.2e-102 341.1 0.0 9.2e-102 340.7 0.0 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Sporozoite_P67 PF05642.11 EAQ84758.1 - 0.96 7.5 7.5 0.061 11.4 0.4 2.0 2 0 0 2 2 2 0 Sporozoite P67 surface antigen DUF4407 PF14362.6 EAQ84759.1 - 1.8 7.8 7.5 3.1 7.1 7.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) BshC PF10079.9 EAQ84759.1 - 1.9 7.1 4.8 2.8 6.6 4.8 1.1 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC C166 PF17615.2 EAQ84761.1 - 5.2e-14 52.7 4.6 7.7e-14 52.1 4.6 1.3 1 0 0 1 1 1 1 Family of unknown function ADH_zinc_N PF00107.26 EAQ84762.1 - 9.4e-11 41.8 0.1 1.6e-10 41.0 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EAQ84762.1 - 5.4e-07 29.5 0.0 9.6e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Pyr_redox PF00070.27 EAQ84762.1 - 0.011 16.3 0.0 0.19 12.3 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase PXB PF12828.7 EAQ84766.1 - 8.9e-42 142.2 0.0 2.1e-41 140.9 0.0 1.7 1 0 0 1 1 1 1 PX-associated DUF3818 PF12825.7 EAQ84766.1 - 1.3e-23 83.6 0.1 1.5e-15 57.1 0.0 2.7 2 1 1 3 3 3 2 Domain of unknown function in PX-proteins (DUF3818) DUF3944 PF13099.6 EAQ84766.1 - 0.038 13.9 0.2 0.19 11.6 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3944) FSA_C PF10479.9 EAQ84766.1 - 0.69 8.0 7.8 1.1 7.3 7.8 1.3 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Cu-oxidase_3 PF07732.15 EAQ84767.1 - 5.8e-27 94.1 0.0 5.8e-26 90.9 0.0 2.5 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.22 EAQ84767.1 - 4.3e-25 88.7 0.0 9e-25 87.6 0.0 1.6 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 EAQ84767.1 - 8.1e-23 80.7 4.6 5.9e-21 74.6 0.9 3.8 3 2 0 3 3 3 2 Multicopper oxidase DUF3245 PF11595.8 EAQ84768.1 - 0.041 14.4 0.6 0.041 14.4 0.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) Thiolase_N PF00108.23 EAQ84770.1 - 6.6e-69 232.2 3.0 8.5e-69 231.8 3.0 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EAQ84770.1 - 4.9e-41 139.2 1.6 1.2e-40 137.9 1.6 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain DUF2681 PF10883.8 EAQ84771.1 - 0.31 11.5 0.7 0.53 10.7 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) DUF347 PF03988.12 EAQ84771.1 - 3.7 7.8 10.7 0.95 9.7 7.0 2.0 2 1 0 2 2 2 0 Repeat of Unknown Function (DUF347) RVT_1 PF00078.27 EAQ84772.1 - 5.4e-48 163.4 0.0 3e-47 161.0 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 EAQ84772.1 - 1.2e-12 47.7 0.0 3.1e-12 46.4 0.0 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 EAQ84772.1 - 2.7e-08 33.6 0.3 9.2e-08 31.9 0.3 2.0 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Vint PF14623.6 EAQ84773.1 - 3.1e-60 202.8 0.0 4.4e-60 202.3 0.0 1.2 1 0 0 1 1 1 1 Hint-domain Vwaint PF14624.6 EAQ84773.1 - 4.4e-28 97.2 0.0 7.9e-28 96.4 0.0 1.4 1 0 0 1 1 1 1 VWA / Hh protein intein-like VWA_2 PF13519.6 EAQ84773.1 - 2.6e-10 40.9 0.0 1.1e-09 38.9 0.0 2.0 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.28 EAQ84773.1 - 2.5e-09 37.6 0.0 5.7e-09 36.5 0.0 1.6 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_3 PF13768.6 EAQ84773.1 - 1.2e-05 25.2 0.0 3.4e-05 23.8 0.0 1.7 2 0 0 2 2 2 1 von Willebrand factor type A domain Ribosomal_L13e PF01294.18 EAQ84774.1 - 1.8e-74 249.5 4.0 2.6e-74 249.0 4.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L13e Ribosomal_L50 PF10501.9 EAQ84775.1 - 3.1e-16 59.5 0.0 7.2e-16 58.3 0.0 1.6 1 0 0 1 1 1 1 Ribosomal subunit 39S HEAT_2 PF13646.6 EAQ84775.1 - 0.11 12.9 10.6 1.3 9.5 0.1 4.3 5 0 0 5 5 5 0 HEAT repeats COX14 PF14880.6 EAQ84776.1 - 8.3e-20 70.4 0.4 8.3e-20 70.4 0.4 1.8 2 0 0 2 2 2 1 Cytochrome oxidase c assembly Pneumo_att_G PF05539.11 EAQ84776.1 - 0.21 11.2 4.4 0.27 10.8 4.4 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G RVT_2 PF07727.14 EAQ84778.1 - 2.1e-44 152.0 0.0 4.1e-44 151.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 EAQ84778.1 - 2.4e-08 34.2 0.0 7.1e-08 32.7 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.6 EAQ84778.1 - 0.0017 18.1 0.0 0.0056 16.5 0.0 1.9 1 0 0 1 1 1 1 GAG-pre-integrase domain PolC_DP2 PF03833.13 EAQ84778.1 - 0.22 9.4 2.7 0.34 8.7 2.7 1.2 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Retrotran_gag_2 PF14223.6 EAQ84778.1 - 0.75 9.5 6.6 0.03 14.0 0.6 1.7 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type zinc_ribbon_15 PF17032.5 EAQ84778.1 - 5.4 7.8 7.7 3.1 8.6 3.6 2.4 2 0 0 2 2 2 0 zinc-ribbon family ketoacyl-synt PF00109.26 EAQ84779.1 - 1.2e-77 260.9 0.4 2.2e-77 260.1 0.4 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EAQ84779.1 - 1e-37 128.7 0.6 2.1e-37 127.7 0.6 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain HTH_51 PF18558.1 EAQ84779.1 - 1.8e-29 101.4 0.0 6.6e-29 99.6 0.0 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain PS-DH PF14765.6 EAQ84779.1 - 2.4e-22 79.5 0.0 4.6e-22 78.6 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Methyltransf_12 PF08242.12 EAQ84779.1 - 4e-18 66.0 0.0 2.9e-17 63.2 0.0 2.6 3 0 0 3 3 2 1 Methyltransferase domain PP-binding PF00550.25 EAQ84779.1 - 3.9e-16 59.1 1.5 8.9e-16 58.0 1.5 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_25 PF13649.6 EAQ84779.1 - 2.1e-13 50.8 0.0 8.3e-12 45.7 0.0 3.4 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 EAQ84779.1 - 6.1e-13 49.2 0.1 5.5e-10 39.8 0.0 3.9 4 0 0 4 4 4 1 Methyltransferase domain SAT PF16073.5 EAQ84779.1 - 1.3e-12 48.0 0.2 9e-12 45.2 0.1 2.2 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Methyltransf_23 PF13489.6 EAQ84779.1 - 3.6e-12 46.4 0.4 1.2e-09 38.2 0.0 3.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAQ84779.1 - 3.5e-07 30.1 0.0 1.1e-06 28.5 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Peptidase_S9 PF00326.21 EAQ84779.1 - 4.5e-06 26.3 0.0 0.0025 17.3 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Thiolase_N PF00108.23 EAQ84779.1 - 7.3e-05 22.3 0.0 0.00013 21.5 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Ubie_methyltran PF01209.18 EAQ84779.1 - 0.00032 20.1 0.0 0.00077 18.9 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Abhydrolase_3 PF07859.13 EAQ84779.1 - 0.0019 18.1 0.0 0.56 10.0 0.0 2.4 2 0 0 2 2 2 1 alpha/beta hydrolase fold Acyl_transf_1 PF00698.21 EAQ84779.1 - 0.0051 16.4 0.1 0.15 11.6 0.0 2.3 2 0 0 2 2 2 1 Acyl transferase domain Methyltransf_33 PF10017.9 EAQ84779.1 - 0.0057 15.8 0.0 0.011 14.8 0.0 1.4 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent DLH PF01738.18 EAQ84779.1 - 0.02 14.5 0.0 1.4 8.4 0.0 3.1 4 0 0 4 4 4 0 Dienelactone hydrolase family Methyltransf_28 PF02636.17 EAQ84779.1 - 0.025 14.2 0.0 0.045 13.4 0.0 1.4 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_16 PF10294.9 EAQ84779.1 - 0.043 13.6 0.0 0.083 12.6 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase p450 PF00067.22 EAQ84780.1 - 2.8e-11 42.8 0.0 3.5e-11 42.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CcmH PF03918.14 EAQ84780.1 - 0.0061 15.9 0.1 0.015 14.6 0.0 1.6 2 0 0 2 2 2 1 Cytochrome C biogenesis protein Lipase_GDSL_2 PF13472.6 EAQ84781.1 - 1.9e-11 44.7 1.3 3.3e-11 43.9 1.3 1.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EAQ84781.1 - 3e-06 27.4 0.0 7.8e-06 26.0 0.0 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 EAQ84781.1 - 0.025 14.7 0.0 0.034 14.3 0.0 1.1 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family RVT_1 PF00078.27 EAQ84782.1 - 2.9e-09 36.8 0.0 4.4e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 EAQ84782.1 - 0.098 13.4 0.0 0.32 11.7 0.0 1.8 2 0 0 2 2 2 0 zinc-binding in reverse transcriptase Questin_oxidase PF14027.6 EAQ84783.1 - 9.8e-58 196.3 1.0 1.2e-57 196.0 1.0 1.1 1 0 0 1 1 1 1 Questin oxidase-like FAD_binding_3 PF01494.19 EAQ84784.1 - 2.1e-13 50.3 0.7 0.0002 20.7 0.1 3.2 3 0 0 3 3 3 3 FAD binding domain Pyr_redox_2 PF07992.14 EAQ84784.1 - 2.7e-07 30.1 1.2 9.6e-05 21.7 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EAQ84784.1 - 7e-07 28.5 0.8 0.00032 19.7 0.1 2.2 2 0 0 2 2 2 2 Tryptophan halogenase FAD_binding_2 PF00890.24 EAQ84784.1 - 2.9e-06 26.6 0.5 4.9e-06 25.9 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EAQ84784.1 - 4e-06 27.0 0.4 4e-06 27.0 0.4 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EAQ84784.1 - 6.8e-06 25.9 0.7 9.2e-05 22.2 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 EAQ84784.1 - 0.0012 18.3 0.1 0.0018 17.7 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EAQ84784.1 - 0.0017 17.1 0.1 0.0032 16.2 0.1 1.4 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.22 EAQ84784.1 - 0.0062 15.7 0.5 0.014 14.5 0.4 1.6 2 0 0 2 2 2 1 Glucose inhibited division protein A Amino_oxidase PF01593.24 EAQ84784.1 - 0.028 13.7 0.5 6.1 6.0 0.0 2.4 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 EAQ84784.1 - 0.054 12.7 0.2 0.11 11.7 0.2 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EAQ84784.1 - 0.067 13.7 1.6 0.17 12.4 0.1 2.4 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase RPA_interact_N PF14766.6 EAQ84784.1 - 0.17 11.5 0.5 0.33 10.6 0.5 1.5 1 0 0 1 1 1 0 Replication protein A interacting N-terminal Lycopene_cycl PF05834.12 EAQ84784.1 - 0.22 10.5 1.8 7 5.6 0.1 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 EAQ84784.1 - 0.3 10.3 1.7 0.67 9.2 0.3 2.0 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Zn_clus PF00172.18 EAQ84785.1 - 1.9e-05 24.7 9.6 1.9e-05 24.7 9.6 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RAP1 PF07218.11 EAQ84785.1 - 0.1 10.9 0.2 0.15 10.3 0.2 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) PSK_trans_fac PF07704.11 EAQ84785.1 - 0.19 12.5 0.1 0.52 11.1 0.1 1.8 1 1 0 1 1 1 0 Rv0623-like transcription factor MFS_1 PF07690.16 EAQ84786.1 - 1.7e-09 37.1 10.5 2.4e-09 36.6 10.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily zf_C2H2_6 PF18450.1 EAQ84786.1 - 0.057 13.1 0.7 0.12 12.2 0.7 1.5 1 0 0 1 1 1 0 Zinc Finger domain Fungal_trans PF04082.18 EAQ84787.1 - 0.00073 18.6 0.1 0.00097 18.2 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DAHP_synth_1 PF00793.20 EAQ84788.1 - 1.7e-106 355.1 0.1 2.1e-106 354.8 0.1 1.0 1 0 0 1 1 1 1 DAHP synthetase I family Cache_3-Cache_2 PF17201.4 EAQ84788.1 - 0.1 11.9 0.3 0.15 11.3 0.3 1.2 1 0 0 1 1 1 0 Cache 3/Cache 2 fusion domain MFS_1 PF07690.16 EAQ84790.1 - 1e-37 129.9 17.9 1e-37 129.9 17.9 3.7 1 1 2 3 3 3 1 Major Facilitator Superfamily TRI12 PF06609.13 EAQ84790.1 - 4.1e-12 45.3 9.7 4.1e-12 45.3 9.7 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EAQ84790.1 - 6.9e-12 45.0 9.5 1.6e-11 43.8 9.5 1.6 1 0 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.20 EAQ84790.1 - 0.024 13.0 0.4 0.039 12.2 0.4 1.4 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family MWFE PF15879.5 EAQ84790.1 - 5.3 7.3 5.3 0.78 10.0 0.3 2.2 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase MWFE subunit Hemerythrin PF01814.23 EAQ84791.1 - 0.12 13.0 0.0 2.1 9.0 0.0 2.6 2 0 0 2 2 2 0 Hemerythrin HHE cation binding domain Podoplanin PF05808.11 EAQ84792.1 - 0.0002 21.5 1.0 0.0003 20.9 1.0 1.3 1 0 0 1 1 1 1 Podoplanin SSP160 PF06933.11 EAQ84792.1 - 0.023 12.9 10.3 0.031 12.5 10.3 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Sporozoite_P67 PF05642.11 EAQ84792.1 - 0.024 12.8 3.5 0.03 12.4 3.5 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Glycophorin_A PF01102.18 EAQ84792.1 - 0.03 14.5 0.3 0.066 13.5 0.3 1.5 1 1 0 1 1 1 0 Glycophorin A SKG6 PF08693.10 EAQ84792.1 - 0.035 13.5 0.7 0.095 12.1 0.7 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain UPF0370 PF13980.6 EAQ84792.1 - 0.13 12.3 0.5 0.26 11.3 0.5 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0370) Plasmodium_Vir PF05795.11 EAQ84792.1 - 0.16 11.4 0.6 0.19 11.1 0.6 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein FAM176 PF14851.6 EAQ84792.1 - 0.25 11.0 4.2 0.39 10.4 4.2 1.3 1 0 0 1 1 1 0 FAM176 family CPSF100_C PF13299.6 EAQ84792.1 - 0.62 10.2 3.4 0.89 9.7 3.4 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal MSP1_C PF07462.11 EAQ84792.1 - 2.6 6.6 3.8 3 6.4 3.8 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus AJAP1_PANP_C PF15298.6 EAQ84792.1 - 3.8 7.7 14.0 1.6 8.9 11.7 1.6 2 0 0 2 2 2 0 AJAP1/PANP C-terminus PAPA-1 PF04795.12 EAQ84792.1 - 6.3 7.7 7.8 0.57 11.0 3.1 1.7 2 0 0 2 2 1 0 PAPA-1-like conserved region LRR_8 PF13855.6 EAQ84793.1 - 1.9e-33 114.0 42.7 2.7e-07 30.2 0.1 8.6 7 2 1 8 8 8 7 Leucine rich repeat LRR_4 PF12799.7 EAQ84793.1 - 2e-27 94.8 45.4 8.3e-07 29.2 1.8 10.1 5 3 9 14 14 14 10 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 EAQ84793.1 - 1.2e-08 34.3 37.3 0.56 10.4 0.1 11.8 13 0 0 13 13 13 4 Leucine Rich repeat LRR_1 PF00560.33 EAQ84793.1 - 2e-07 30.6 37.5 2.5 9.0 0.2 12.9 13 0 0 13 13 13 4 Leucine Rich Repeat LRR_9 PF14580.6 EAQ84793.1 - 0.00027 20.5 13.6 0.83 9.1 0.0 5.1 2 2 4 6 6 6 4 Leucine-rich repeat DPM3 PF08285.11 EAQ84794.1 - 1.4e-34 118.2 0.1 1.5e-34 118.0 0.1 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Oxidored-like PF09791.9 EAQ84796.1 - 3.3e-24 84.3 5.8 3.3e-24 84.3 5.8 2.3 2 0 0 2 2 2 1 Oxidoreductase-like protein, N-terminal Pribosyltran PF00156.27 EAQ84797.1 - 4.3e-07 29.6 0.0 6.7e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Inv-AAD PF18785.1 EAQ84799.1 - 1.2e-51 173.9 0.0 1.4e-51 173.7 0.0 1.1 1 0 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase dCMP_cyt_deam_1 PF00383.23 EAQ84799.1 - 7.8e-15 54.6 0.0 1e-14 54.2 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.11 EAQ84799.1 - 0.00033 20.6 0.0 0.00057 19.8 0.0 1.3 1 1 0 1 1 1 1 APOBEC-like N-terminal domain SNAD4 PF18750.1 EAQ84799.1 - 0.035 14.2 0.0 0.053 13.6 0.0 1.3 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 MafB19-deam PF14437.6 EAQ84799.1 - 0.099 12.4 0.0 0.16 11.7 0.0 1.5 1 1 0 1 1 1 0 MafB19-like deaminase MAGE_N PF12440.8 EAQ84801.1 - 0.018 15.7 0.1 0.018 15.7 0.1 3.8 4 1 0 4 4 4 0 Melanoma associated antigen family N terminal CDC45 PF02724.14 EAQ84801.1 - 8.2 4.6 7.2 14 3.9 7.2 1.2 1 0 0 1 1 1 0 CDC45-like protein Pkinase PF00069.25 EAQ84802.1 - 3.8e-40 137.9 0.0 5.2e-40 137.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ84802.1 - 2e-21 76.5 0.0 3.5e-21 75.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAQ84802.1 - 2.3e-05 23.9 0.0 5.1e-05 22.7 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EAQ84802.1 - 0.033 13.0 0.0 0.048 12.4 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 EAQ84802.1 - 0.073 12.4 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FeS PF04060.13 EAQ84804.1 - 0.024 14.3 2.7 0.024 14.3 2.7 1.5 2 0 0 2 2 2 0 Putative Fe-S cluster PLAC8 PF04749.17 EAQ84805.1 - 6e-22 78.5 17.1 7.5e-22 78.2 17.1 1.1 1 0 0 1 1 1 1 PLAC8 family DUF1289 PF06945.13 EAQ84807.1 - 0.54 10.1 14.4 0.13 12.1 2.6 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1289) Fungal_trans PF04082.18 EAQ84808.1 - 2.9e-12 46.2 0.1 6.2e-12 45.1 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Med21 PF11221.8 EAQ84808.1 - 0.15 12.3 0.1 0.29 11.4 0.1 1.5 1 0 0 1 1 1 0 Subunit 21 of Mediator complex PIF1 PF05970.14 EAQ84809.1 - 5.5e-20 71.9 0.0 8.4e-20 71.3 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 EAQ84809.1 - 1.3e-08 34.8 0.0 8.1e-08 32.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EAQ84809.1 - 0.0002 21.7 0.0 0.00045 20.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain Ank_2 PF12796.7 EAQ84810.1 - 7.2e-103 337.4 26.8 1.9e-16 60.4 0.1 9.3 1 1 8 9 9 9 9 Ankyrin repeats (3 copies) Ank PF00023.30 EAQ84810.1 - 3.9e-61 201.0 21.3 0.0017 18.7 0.0 14.7 14 0 0 14 14 14 12 Ankyrin repeat Ank_4 PF13637.6 EAQ84810.1 - 3.1e-58 193.4 8.7 6e-07 29.9 0.1 13.0 1 1 12 13 13 13 13 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAQ84810.1 - 9.7e-55 181.9 1.1 0.00051 20.3 0.0 12.0 1 1 11 12 12 12 12 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAQ84810.1 - 7.1e-34 112.0 3.3 0.42 11.3 0.0 14.7 14 0 0 14 14 14 6 Ankyrin repeat PNP_UDP_1 PF01048.20 EAQ84810.1 - 5.2e-08 32.4 0.2 2.1e-07 30.4 0.2 1.9 1 1 0 1 1 1 1 Phosphorylase superfamily NACHT PF05729.12 EAQ84810.1 - 5.5e-08 32.9 0.2 1.1e-07 31.9 0.2 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EAQ84810.1 - 3.9e-05 24.1 1.3 9.4e-05 22.9 0.4 2.1 2 0 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.22 EAQ84810.1 - 0.023 13.9 0.1 0.061 12.5 0.1 1.8 1 1 0 1 1 1 0 NB-ARC domain Amidinotransf PF02274.17 EAQ84810.1 - 0.024 13.8 1.9 2.9 6.9 0.0 4.2 2 2 1 3 3 3 0 Amidinotransferase AAA_14 PF13173.6 EAQ84810.1 - 0.037 14.1 0.1 0.82 9.7 0.0 3.0 2 1 0 2 2 2 0 AAA domain YajC PF02699.15 EAQ84810.1 - 0.04 13.8 20.3 31 4.5 0.0 9.2 3 2 8 11 11 11 0 Preprotein translocase subunit UPF0184 PF03670.13 EAQ84810.1 - 0.056 13.8 0.1 0.15 12.5 0.1 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) ATPase_2 PF01637.18 EAQ84810.1 - 0.059 13.3 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_22 PF13401.6 EAQ84810.1 - 0.066 13.5 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain PIF1 PF05970.14 EAQ84811.1 - 3.9e-14 52.6 0.0 7.5e-14 51.7 0.0 1.3 1 0 0 1 1 1 1 PIF1-like helicase PNP_UDP_1 PF01048.20 EAQ84811.1 - 1.8e-08 34.0 0.1 1e-07 31.5 0.1 2.3 2 1 0 2 2 2 1 Phosphorylase superfamily Focal_AT PF03623.13 EAQ84811.1 - 0.011 15.8 0.1 0.034 14.1 0.1 1.8 1 0 0 1 1 1 0 Focal adhesion targeting region UvrD_C_2 PF13538.6 EAQ84811.1 - 0.023 14.5 0.0 0.066 13.1 0.0 1.9 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain NACHT PF05729.12 EAQ84811.1 - 0.074 13.0 0.1 0.18 11.7 0.1 1.6 1 0 0 1 1 1 0 NACHT domain AAA_30 PF13604.6 EAQ84811.1 - 0.076 12.7 0.0 0.29 10.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain RVT_1 PF00078.27 EAQ84812.1 - 1.8e-23 83.2 0.0 3.1e-23 82.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 EAQ84812.1 - 0.0023 17.9 1.7 0.0023 17.9 1.7 2.7 2 0 0 2 2 2 1 Zinc knuckle KELK PF15796.5 EAQ84812.1 - 1.5 9.3 4.5 4.8 7.7 0.9 2.8 2 0 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase RVT_1 PF00078.27 EAQ84813.1 - 6.2e-18 65.1 0.0 1.1e-17 64.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 EAQ84813.1 - 0.14 12.9 0.0 0.4 11.4 0.0 1.8 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase AAA_16 PF13191.6 EAQ84814.1 - 1e-08 35.8 2.3 6.6e-07 29.9 2.0 2.9 1 1 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 EAQ84814.1 - 4.5e-07 29.9 1.8 0.0012 18.8 0.0 3.1 2 1 0 2 2 2 2 NACHT domain AAA_22 PF13401.6 EAQ84814.1 - 0.00012 22.3 1.4 0.0094 16.2 1.4 2.7 1 1 0 1 1 1 1 AAA domain AAA_23 PF13476.6 EAQ84814.1 - 0.002 18.7 8.7 0.78 10.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 EAQ84814.1 - 0.003 17.9 0.1 0.0076 16.6 0.1 1.7 1 0 0 1 1 1 1 RNA helicase NB-ARC PF00931.22 EAQ84814.1 - 0.0037 16.5 0.0 0.0086 15.3 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain ATPase_2 PF01637.18 EAQ84814.1 - 0.0056 16.6 0.5 0.025 14.5 0.0 2.3 3 0 0 3 3 3 1 ATPase domain predominantly from Archaea ABC_tran PF00005.27 EAQ84814.1 - 0.026 15.0 0.1 0.078 13.5 0.1 1.8 1 1 0 1 1 1 0 ABC transporter DUF676 PF05057.14 EAQ84814.1 - 0.031 13.8 0.0 0.061 12.8 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Viral_helicase1 PF01443.18 EAQ84814.1 - 0.048 13.4 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_33 PF13671.6 EAQ84814.1 - 0.06 13.5 0.0 0.19 11.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain GAS PF13851.6 EAQ84814.1 - 0.082 12.3 4.9 0.16 11.3 4.9 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding ZapB PF06005.12 EAQ84814.1 - 0.1 13.1 10.4 0.89 10.0 8.3 2.6 2 0 0 2 2 2 0 Cell division protein ZapB AAA_30 PF13604.6 EAQ84814.1 - 0.12 12.0 0.0 0.51 10.0 0.0 2.0 2 0 0 2 2 1 0 AAA domain Nsp1_C PF05064.13 EAQ84814.1 - 0.15 11.9 2.9 0.36 10.7 2.9 1.6 1 0 0 1 1 1 0 Nsp1-like C-terminal region AAA PF00004.29 EAQ84814.1 - 0.17 12.3 0.0 2.2 8.7 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 EAQ84814.1 - 0.2 11.4 3.3 9.7 5.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain UPF0242 PF06785.11 EAQ84814.1 - 0.21 11.7 5.7 0.43 10.7 5.7 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF724 PF05266.14 EAQ84814.1 - 0.43 10.4 4.9 12 5.6 3.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Jnk-SapK_ap_N PF09744.9 EAQ84814.1 - 0.77 10.0 6.9 1.4 9.1 6.9 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 MFS_1 PF07690.16 EAQ84815.1 - 6.4e-10 38.5 49.8 4.2e-05 22.7 16.4 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EAQ84815.1 - 0.0062 15.0 19.0 0.0049 15.4 16.4 1.9 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) adh_short PF00106.25 EAQ84816.1 - 0.0017 17.9 0.2 0.47 9.9 0.0 2.7 2 1 1 3 3 3 2 short chain dehydrogenase Transketolase_C PF02780.20 EAQ84816.1 - 0.066 13.1 0.1 0.51 10.2 0.1 2.3 1 1 1 2 2 2 0 Transketolase, C-terminal domain LRRFIP PF09738.9 EAQ84817.1 - 0.012 15.1 0.0 0.023 14.2 0.0 1.4 1 0 0 1 1 1 0 LRRFIP family HMGL-like PF00682.19 EAQ84818.1 - 5.7e-34 117.9 0.2 1.6e-24 86.9 0.0 2.3 1 1 1 2 2 2 2 HMGL-like DUF4213 PF13938.6 EAQ84818.1 - 0.14 12.4 0.0 6.8 7.0 0.0 2.4 2 0 0 2 2 2 0 Putative heavy-metal chelation TANGO2 PF05742.12 EAQ84821.1 - 5.2e-63 213.4 0.0 1.8e-61 208.4 0.0 2.0 1 1 0 1 1 1 1 Transport and Golgi organisation 2 Tfb2 PF03849.14 EAQ84823.1 - 2.6e-133 444.4 0.0 3.3e-133 444.1 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 EAQ84823.1 - 4.8e-20 71.7 0.7 8.9e-20 70.9 0.7 1.5 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 EAQ84823.1 - 5.5e-05 23.3 0.1 0.00011 22.3 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain 4HBT PF03061.22 EAQ84824.1 - 1.7e-13 50.7 0.1 2.7e-13 50.0 0.1 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 EAQ84824.1 - 0.0042 17.4 0.1 0.0079 16.5 0.1 1.4 1 1 0 1 1 1 1 Thioesterase-like superfamily Peptidase_A4 PF01828.17 EAQ84825.1 - 3.5e-60 203.1 0.4 4.1e-60 202.8 0.4 1.0 1 0 0 1 1 1 1 Peptidase A4 family CBP_BcsG PF11658.8 EAQ84827.1 - 9.1e-05 21.0 0.9 0.00016 20.3 0.9 1.3 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsG COX6C PF02937.15 EAQ84827.1 - 0.078 13.1 0.2 0.28 11.4 0.2 1.9 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIc MFS_1 PF07690.16 EAQ84828.1 - 2.5e-21 76.0 23.9 7.6e-21 74.4 23.9 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily MASE2 PF05230.11 EAQ84828.1 - 0.46 10.6 5.5 0.91 9.6 2.4 2.3 2 0 0 2 2 2 0 MASE2 domain HTH_Tnp_Tc5 PF03221.16 EAQ84830.1 - 3.5e-12 46.2 0.0 5.7e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.16 EAQ84830.1 - 4.4e-06 26.3 0.0 7.1e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_23 PF13384.6 EAQ84830.1 - 0.0062 16.3 0.2 0.053 13.3 0.0 2.5 3 1 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 EAQ84830.1 - 0.013 15.6 0.8 0.12 12.5 0.0 2.7 2 1 1 3 3 3 0 Helix-turn-helix domain CENP-B_N PF04218.13 EAQ84830.1 - 0.09 12.4 0.0 0.3 10.8 0.0 1.9 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain Phage_CP76 PF06892.11 EAQ84830.1 - 0.1 12.1 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Phage regulatory protein CII (CP76) TB2_DP1_HVA22 PF03134.19 EAQ84831.1 - 3e-27 94.4 7.2 4.7e-27 93.7 7.2 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family DUF3446 PF11928.8 EAQ84831.1 - 2 8.7 16.0 2.9 8.3 8.8 2.6 1 1 1 2 2 2 0 Early growth response N-terminal domain MSP1_C PF07462.11 EAQ84831.1 - 3.8 6.1 4.2 4.2 5.9 2.4 1.9 2 1 0 2 2 2 0 Merozoite surface protein 1 (MSP1) C-terminus Mgm101p PF06420.12 EAQ84832.1 - 1.7e-86 288.1 0.0 2e-86 287.8 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 FAP PF07174.11 EAQ84832.1 - 0.76 9.2 23.9 0.79 9.1 22.3 1.8 2 0 0 2 2 2 0 Fibronectin-attachment protein (FAP) CHCH PF06747.13 EAQ84833.1 - 9.7e-06 25.6 3.8 1.2e-05 25.3 3.8 1.2 1 0 0 1 1 1 1 CHCH domain BPL_N PF09825.9 EAQ84834.1 - 3.2e-147 490.5 0.0 3.9e-147 490.2 0.0 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.19 EAQ84834.1 - 1.3e-21 76.8 0.0 2.6e-21 75.9 0.0 1.5 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family DUF4381 PF14316.6 EAQ84836.1 - 0.093 13.0 0.3 0.18 12.0 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) HeLo PF14479.6 EAQ84837.1 - 7.2e-29 101.1 0.0 1e-28 100.6 0.0 1.2 1 0 0 1 1 1 1 Prion-inhibition and propagation Dfp1_Him1_M PF08630.10 EAQ84837.1 - 0.051 13.8 0.2 0.59 10.4 0.0 2.2 2 0 0 2 2 2 0 Dfp1/Him1, central region Rota_VP4_MID PF17477.2 EAQ84837.1 - 0.1 11.9 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Rotavirus VP4 membrane interaction domain WD40 PF00400.32 EAQ84838.1 - 9.2e-74 241.5 28.5 3.1e-11 43.6 0.1 8.2 8 0 0 8 8 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAQ84838.1 - 6.7e-26 90.4 0.0 0.0021 18.3 0.0 6.5 1 1 5 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 EAQ84838.1 - 5.8e-20 71.9 0.1 1.1e-19 71.0 0.1 1.5 1 0 0 1 1 1 1 NACHT domain Ge1_WD40 PF16529.5 EAQ84838.1 - 6.2e-17 61.6 8.8 0.08 11.9 0.1 6.2 1 1 5 6 6 6 6 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 EAQ84838.1 - 2e-11 43.5 0.1 11 6.1 0.0 6.6 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat Proteasome_A_N PF10584.9 EAQ84838.1 - 7.5e-07 28.7 3.0 39 4.0 0.0 6.3 6 0 0 6 6 6 0 Proteasome subunit A N-terminal signature DUF642 PF04862.12 EAQ84838.1 - 1.6e-06 28.0 3.4 0.088 12.6 0.1 4.7 1 1 2 3 3 3 2 Protein of unknown function (DUF642) WD40_like PF17005.5 EAQ84838.1 - 2.2e-05 23.9 0.0 6.8 5.9 0.0 5.0 4 1 2 6 6 6 2 WD40-like domain AAA_16 PF13191.6 EAQ84838.1 - 3.6e-05 24.2 0.4 0.00013 22.4 0.1 2.1 2 0 0 2 2 2 1 AAA ATPase domain Cytochrom_D1 PF02239.16 EAQ84838.1 - 0.00096 17.8 2.0 0.22 10.0 0.1 2.6 1 1 2 3 3 3 3 Cytochrome D1 heme domain PQQ_3 PF13570.6 EAQ84838.1 - 0.0011 19.3 17.7 8.9 7.0 0.3 6.3 6 0 0 6 6 6 1 PQQ-like domain Ret2_MD PF18528.1 EAQ84838.1 - 0.002 18.4 0.0 1e+02 3.4 0.0 5.4 2 2 4 6 6 6 0 RNA editing 3' terminal uridylyl transferase 2 middle domain Robl_LC7 PF03259.17 EAQ84838.1 - 0.0027 17.4 0.6 16 5.4 0.0 4.3 3 1 1 4 4 4 0 Roadblock/LC7 domain RVT_3 PF13456.6 EAQ84838.1 - 0.015 15.1 0.0 0.045 13.6 0.0 1.8 1 0 0 1 1 1 0 Reverse transcriptase-like AAA_22 PF13401.6 EAQ84838.1 - 0.044 14.1 0.0 0.16 12.2 0.0 2.0 1 1 1 2 2 2 0 AAA domain TruB_C PF09142.11 EAQ84838.1 - 0.047 13.5 7.7 1.4e+02 2.4 0.0 5.9 6 0 0 6 6 6 0 tRNA Pseudouridine synthase II, C terminal DUF5570 PF17731.1 EAQ84838.1 - 1.9 8.6 25.2 23 5.1 0.2 6.5 1 1 5 6 6 6 0 Family of unknown function (DUF5570) Cadherin_4 PF17803.1 EAQ84838.1 - 5.7 7.6 6.6 2.3e+02 2.5 0.1 4.3 1 1 2 3 3 3 0 Bacterial cadherin-like domain Pam16 PF03656.13 EAQ84839.1 - 6.3e-34 116.7 0.8 7.6e-34 116.5 0.8 1.0 1 0 0 1 1 1 1 Pam16 Yip1 PF04893.17 EAQ84840.1 - 1.8e-06 27.8 17.7 0.0039 16.9 9.4 2.8 2 1 1 3 3 3 2 Yip1 domain RCC1 PF00415.18 EAQ84841.1 - 8.1e-57 189.7 3.3 5.3e-08 33.4 0.0 7.4 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EAQ84841.1 - 6.1e-40 134.2 18.8 1.4e-07 31.1 0.2 6.3 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat Methyltransf_16 PF10294.9 EAQ84843.1 - 4.9e-17 62.2 0.0 7.1e-17 61.7 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_31 PF13847.6 EAQ84843.1 - 0.033 14.0 0.0 0.047 13.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 EAQ84843.1 - 0.052 14.2 0.0 0.11 13.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 EAQ84843.1 - 0.11 12.0 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain DAO PF01266.24 EAQ84852.1 - 1.6e-33 116.7 3.9 2.3e-33 116.2 3.9 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Methyltransf_23 PF13489.6 EAQ84853.1 - 3e-20 72.7 0.0 5.8e-20 71.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EAQ84853.1 - 4.4e-11 43.4 0.1 3.1e-10 40.7 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAQ84853.1 - 9.1e-11 42.3 0.0 2.6e-10 40.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EAQ84853.1 - 1.3e-09 38.6 0.0 3.8e-09 37.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAQ84853.1 - 4.5e-08 33.0 0.0 3.1e-07 30.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 EAQ84853.1 - 0.0062 15.8 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_PK PF05891.12 EAQ84853.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Ubie_methyltran PF01209.18 EAQ84853.1 - 0.17 11.2 0.0 0.34 10.2 0.0 1.5 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family HgmA PF04209.13 EAQ84854.1 - 1.3e-126 422.8 0.2 1e-93 314.4 0.5 2.0 1 1 1 2 2 2 2 homogentisate 1,2-dioxygenase Big_4 PF07532.11 EAQ84854.1 - 0.18 11.6 0.4 0.54 10.0 0.4 1.7 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 4) Helitron_like_N PF14214.6 EAQ84856.1 - 1.8e-36 126.1 3.4 4.4e-36 124.9 3.4 1.7 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.14 EAQ84856.1 - 3.1e-25 89.1 0.0 2.1e-21 76.5 0.0 2.2 2 0 0 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 EAQ84856.1 - 3.8e-10 39.8 0.0 8.7e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAQ84856.1 - 4.6e-06 27.0 0.0 9.2e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain Herpes_Helicase PF02689.14 EAQ84856.1 - 0.0018 16.3 0.0 0.0056 14.7 0.1 1.6 2 0 0 2 2 2 1 Helicase AAA_11 PF13086.6 EAQ84856.1 - 0.0072 16.1 0.0 2.6 7.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain UvrD_C_2 PF13538.6 EAQ84856.1 - 0.0074 16.1 0.5 0.021 14.7 0.5 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain SH3_13 PF18335.1 EAQ84856.1 - 0.065 13.1 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 ATP-dependent RecD-like DNA helicase SH3 domain AAA_22 PF13401.6 EAQ84856.1 - 0.11 12.8 0.0 0.29 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain Nif11 PF07862.11 EAQ84856.1 - 1.7 9.0 0.0 1.7 9.0 0.0 2.7 4 0 0 4 4 4 0 Nif11 domain Acyl-CoA_dh_2 PF08028.11 EAQ84859.1 - 0.025 14.9 1.4 0.13 12.5 0.2 2.0 1 1 1 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain FUSC PF04632.12 EAQ84859.1 - 0.26 9.8 4.8 0.33 9.4 4.8 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family ANAPC4_WD40 PF12894.7 EAQ84860.1 - 0.0026 18.0 0.0 1.9 8.8 0.0 2.7 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nop14 PF04147.12 EAQ84861.1 - 0.086 11.0 2.2 0.13 10.5 2.2 1.2 1 0 0 1 1 1 0 Nop14-like family WD40 PF00400.32 EAQ84862.1 - 3.4e-52 173.3 13.3 1.3e-07 32.1 0.9 8.6 8 1 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAQ84862.1 - 5e-09 36.3 0.3 0.013 15.8 0.0 4.5 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EAQ84862.1 - 2e-05 23.4 0.2 0.087 11.4 0.0 3.8 3 1 1 4 4 4 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 EAQ84862.1 - 0.0078 15.0 0.0 0.13 11.0 0.0 2.5 2 1 0 2 2 2 1 Nup133 N terminal like NAD_binding_1 PF00175.21 EAQ84863.1 - 0.19 12.4 0.1 0.35 11.5 0.1 1.4 1 0 0 1 1 1 0 Oxidoreductase NAD-binding domain UPF0242 PF06785.11 EAQ84863.1 - 0.46 10.6 5.1 0.88 9.6 5.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Herpes_UL25 PF01499.16 EAQ84863.1 - 2.3 6.7 9.2 2.7 6.4 2.7 2.2 2 0 0 2 2 2 0 Herpesvirus UL25 family DUF1003 PF06210.11 EAQ84863.1 - 2.7 8.1 4.2 5.6 7.1 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1003) RRM_1 PF00076.22 EAQ84865.1 - 2.8e-12 46.3 0.1 5.3e-12 45.4 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EAQ84865.1 - 0.0027 17.6 0.0 0.0059 16.6 0.0 1.6 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 EAQ84865.1 - 0.015 15.3 0.0 0.035 14.2 0.0 1.6 1 0 0 1 1 1 0 RNA binding motif RRM_occluded PF16842.5 EAQ84865.1 - 0.035 14.0 0.0 0.075 12.9 0.0 1.6 1 0 0 1 1 1 0 Occluded RNA-recognition motif Phage_antitermQ PF06530.12 EAQ84866.1 - 0.083 12.8 0.1 0.17 11.8 0.1 1.5 1 0 0 1 1 1 0 Phage antitermination protein Q Ank_2 PF12796.7 EAQ84868.1 - 3.3e-90 296.8 10.5 4.5e-19 68.8 0.1 6.2 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAQ84868.1 - 4.2e-52 173.9 5.2 9.6e-10 38.8 0.0 7.9 3 2 3 7 7 7 7 Ankyrin repeats (many copies) Ank PF00023.30 EAQ84868.1 - 3.2e-50 166.5 2.2 4.4e-06 26.9 0.1 10.4 10 0 0 10 10 10 8 Ankyrin repeat Ank_3 PF13606.6 EAQ84868.1 - 5.1e-46 149.3 0.1 6e-05 23.1 0.0 9.6 10 0 0 10 10 10 8 Ankyrin repeat Ank_5 PF13857.6 EAQ84868.1 - 9.6e-38 127.8 3.2 4e-09 36.6 0.2 8.7 3 2 6 9 9 9 9 Ankyrin repeats (many copies) VWA_3_C PF18571.1 EAQ84868.1 - 0.019 14.8 0.4 16 5.5 0.0 4.3 5 0 0 5 5 5 0 von Willebrand factor type A C-terminal domain GATase_7 PF13537.6 EAQ84868.1 - 0.12 12.2 0.1 36 4.3 0.0 4.1 3 2 1 4 4 4 0 Glutamine amidotransferase domain AAA PF00004.29 EAQ84869.1 - 2.5e-16 60.3 0.0 4.6e-16 59.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EAQ84869.1 - 0.0017 18.6 0.1 0.0054 17.0 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EAQ84869.1 - 0.0023 17.9 0.0 0.0065 16.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EAQ84869.1 - 0.0043 17.5 0.1 0.011 16.1 0.1 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 EAQ84869.1 - 0.11 12.2 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EAQ84869.1 - 0.15 12.2 0.1 0.83 9.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain Hydin_ADK PF17213.3 EAQ84869.1 - 0.23 11.7 0.1 0.43 10.8 0.1 1.4 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain AF-4 PF05110.13 EAQ84870.1 - 0.00013 20.3 0.5 0.00019 19.7 0.5 1.1 1 0 0 1 1 1 1 AF-4 proto-oncoprotein HEXIM PF15313.6 EAQ84870.1 - 0.019 15.2 6.2 0.17 12.0 0.4 2.3 2 0 0 2 2 2 0 Hexamethylene bis-acetamide-inducible protein ABC2_membrane PF01061.24 EAQ84871.1 - 2.4e-38 131.7 20.3 2.4e-38 131.7 20.3 2.0 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 EAQ84871.1 - 3.3e-18 66.5 0.0 5.4e-18 65.8 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EAQ84871.1 - 7.2e-07 29.3 0.0 0.032 14.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_33 PF13671.6 EAQ84871.1 - 0.00054 20.1 0.6 0.002 18.3 0.0 2.2 3 0 0 3 3 2 1 AAA domain RsgA_GTPase PF03193.16 EAQ84871.1 - 0.00059 19.8 0.0 0.0012 18.8 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 EAQ84871.1 - 0.00085 19.7 0.0 0.0016 18.9 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 EAQ84871.1 - 0.0015 18.3 0.1 0.0037 17.0 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.6 EAQ84871.1 - 0.0028 17.3 0.1 0.0054 16.3 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EAQ84871.1 - 0.0047 17.5 0.7 0.01 16.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 EAQ84871.1 - 0.005 16.3 0.0 0.32 10.4 0.0 2.2 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_28 PF13521.6 EAQ84871.1 - 0.013 15.8 0.0 0.029 14.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain PDR_CDR PF06422.12 EAQ84871.1 - 0.019 14.8 0.1 0.21 11.5 0.0 2.6 2 0 0 2 2 2 0 CDR ABC transporter AAA_22 PF13401.6 EAQ84871.1 - 0.05 13.9 0.1 0.17 12.1 0.1 1.9 1 1 0 1 1 1 0 AAA domain cobW PF02492.19 EAQ84871.1 - 0.069 12.7 0.2 0.12 12.0 0.2 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.6 EAQ84871.1 - 0.1 13.0 0.0 0.1 13.0 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_23 PF13476.6 EAQ84871.1 - 0.18 12.2 0.0 0.18 12.2 0.0 1.8 2 0 0 2 2 1 0 AAA domain ABC2_membrane_3 PF12698.7 EAQ84871.1 - 1.4 8.0 19.4 1.4 8.0 18.0 1.7 1 1 0 1 1 1 0 ABC-2 family transporter protein CK_II_beta PF01214.18 EAQ84872.1 - 5.1e-75 251.3 0.0 9.2e-75 250.4 0.0 1.4 1 1 0 1 1 1 1 Casein kinase II regulatory subunit RRN3 PF05327.11 EAQ84872.1 - 0.091 11.3 1.7 0.14 10.7 1.7 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Sporozoite_P67 PF05642.11 EAQ84872.1 - 0.15 10.1 0.1 0.22 9.6 0.1 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PBP1_TM PF14812.6 EAQ84872.1 - 0.34 11.3 8.4 0.67 10.4 2.3 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Spt5_N PF11942.8 EAQ84872.1 - 0.72 10.9 12.2 0.21 12.6 5.5 2.4 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal PTPRCAP PF15713.5 EAQ84872.1 - 1.7 8.9 10.1 3.6 7.9 5.2 2.1 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated FAM176 PF14851.6 EAQ84872.1 - 5.1 6.8 6.1 3.4 7.3 2.5 2.0 2 0 0 2 2 2 0 FAM176 family Cupin_8 PF13621.6 EAQ84873.1 - 2.5e-22 79.8 0.0 3.7e-22 79.3 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain Cupin_2 PF07883.11 EAQ84873.1 - 0.00097 18.8 0.0 0.0034 17.1 0.0 1.8 2 0 0 2 2 2 1 Cupin domain Cupin_4 PF08007.12 EAQ84873.1 - 0.033 13.7 0.0 0.084 12.3 0.0 1.6 2 0 0 2 2 2 0 Cupin superfamily protein Cupin_1 PF00190.22 EAQ84873.1 - 0.17 11.5 0.0 0.28 10.8 0.0 1.3 1 0 0 1 1 1 0 Cupin DUF1295 PF06966.12 EAQ84874.1 - 1.9e-14 53.7 3.8 5.2e-14 52.3 3.8 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.16 EAQ84874.1 - 0.0077 16.2 0.3 0.017 15.1 0.3 1.6 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.13 EAQ84874.1 - 0.1 13.0 0.2 0.26 11.7 0.2 1.7 1 0 0 1 1 1 0 Phospholipid methyltransferase PEPCK_ATP PF01293.20 EAQ84875.1 - 4.3e-153 510.3 0.0 1.5e-139 465.7 0.0 2.0 1 1 0 2 2 2 2 Phosphoenolpyruvate carboxykinase AAA_16 PF13191.6 EAQ84875.1 - 0.11 12.9 0.0 0.18 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 EAQ84875.1 - 0.17 12.0 0.0 0.32 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain p450 PF00067.22 EAQ84876.1 - 1.2e-13 50.7 0.0 7.4e-13 48.1 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 EF-hand_1 PF00036.32 EAQ84878.1 - 4.9e-17 60.1 4.4 1.1e-07 30.9 0.2 3.2 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 EAQ84878.1 - 5.2e-17 60.3 4.0 1.6e-07 30.7 0.3 3.1 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 EAQ84878.1 - 1.8e-16 60.3 1.5 1.5e-08 35.0 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 EAQ84878.1 - 2.6e-13 49.6 2.4 0.00028 20.7 0.1 3.2 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 EAQ84878.1 - 8.1e-10 37.7 7.1 2.7e-05 23.4 0.4 2.9 3 0 0 3 3 3 2 EF hand Caleosin PF05042.13 EAQ84878.1 - 0.00026 20.9 0.0 0.1 12.5 0.0 2.1 2 0 0 2 2 2 2 Caleosin related protein EF-hand_9 PF14658.6 EAQ84878.1 - 0.019 15.3 0.0 0.74 10.2 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain EFhand_Ca_insen PF08726.10 EAQ84878.1 - 0.038 14.1 0.0 0.13 12.4 0.0 1.8 1 0 0 1 1 1 0 Ca2+ insensitive EF hand EF-hand_4 PF12763.7 EAQ84878.1 - 0.051 13.5 0.1 0.52 10.3 0.1 2.1 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 EAQ84878.1 - 0.17 12.2 0.0 1.1 9.6 0.0 1.9 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region BUD22 PF09073.10 EAQ84879.1 - 1.8e-65 222.0 49.6 7.8e-51 173.8 43.0 2.1 1 1 1 2 2 2 2 BUD22 TMF_DNA_bd PF12329.8 EAQ84880.1 - 0.068 13.2 2.8 0.12 12.4 2.8 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding APG6_N PF17675.1 EAQ84880.1 - 0.14 12.7 2.6 0.22 12.0 2.6 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region ZapB PF06005.12 EAQ84880.1 - 0.3 11.6 4.6 0.64 10.5 4.6 1.5 1 0 0 1 1 1 0 Cell division protein ZapB Sas6_CC PF18594.1 EAQ84880.1 - 0.37 10.6 1.2 11 5.9 0.4 2.6 2 0 0 2 2 2 0 Sas6/XLF/XRCC4 coiled-coil domain YabA PF06156.13 EAQ84880.1 - 0.43 11.2 2.5 0.87 10.3 2.5 1.5 1 0 0 1 1 1 0 Initiation control protein YabA DivIC PF04977.15 EAQ84880.1 - 0.71 9.7 3.2 1.3 8.9 1.0 2.1 1 1 1 2 2 2 0 Septum formation initiator TSC22 PF01166.18 EAQ84880.1 - 0.88 9.9 5.6 1.1 9.6 0.9 2.4 1 1 1 2 2 2 0 TSC-22/dip/bun family ATG13 PF10033.9 EAQ84881.1 - 2.2e-71 240.3 0.0 3.6e-71 239.6 0.0 1.3 1 0 0 1 1 1 1 Autophagy-related protein 13 Med3 PF11593.8 EAQ84881.1 - 0.0062 15.8 8.6 0.0062 15.8 8.6 1.9 1 1 1 2 2 2 1 Mediator complex subunit 3 fungal RCC1 PF00415.18 EAQ84883.1 - 1.5e-18 67.1 2.5 2.4e-06 28.0 0.1 4.5 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 EAQ84883.1 - 7.1e-12 45.5 0.0 2.1e-07 31.2 0.0 2.5 2 0 0 2 2 2 2 BTB/POZ domain Ank_4 PF13637.6 EAQ84883.1 - 4.3e-11 43.1 0.1 9.8e-11 42.0 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAQ84883.1 - 2.8e-06 27.8 0.0 8.2e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) RCC1_2 PF13540.6 EAQ84883.1 - 9.3e-06 25.3 0.4 9.3e-06 25.3 0.4 3.5 4 0 0 4 4 4 2 Regulator of chromosome condensation (RCC1) repeat Ank_3 PF13606.6 EAQ84883.1 - 1.8e-05 24.7 0.2 0.22 12.2 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 EAQ84883.1 - 0.028 14.7 0.2 0.34 11.3 0.1 2.7 1 1 1 2 2 2 0 Ankyrin repeats (many copies) Mito_carr PF00153.27 EAQ84884.1 - 1.1e-53 179.1 1.9 8e-20 70.6 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Antimicrobial_8 PF08103.11 EAQ84884.1 - 0.085 13.0 0.2 16 5.9 0.0 2.5 2 0 0 2 2 2 0 Uperin family VHS PF00790.19 EAQ84885.1 - 5.1e-35 120.4 0.1 9.9e-35 119.4 0.1 1.5 1 0 0 1 1 1 1 VHS domain SH3_1 PF00018.28 EAQ84885.1 - 1.5e-16 59.8 0.1 3.1e-16 58.7 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EAQ84885.1 - 7.1e-15 54.6 0.1 1.6e-14 53.5 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EAQ84885.1 - 3.2e-13 49.1 0.0 5.4e-13 48.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain UIM PF02809.20 EAQ84885.1 - 0.012 15.5 2.4 0.031 14.2 2.4 1.7 1 0 0 1 1 1 0 Ubiquitin interaction motif Fungal_trans PF04082.18 EAQ84886.1 - 4.3e-06 26.0 0.9 0.00054 19.1 0.0 2.6 2 0 0 2 2 2 2 Fungal specific transcription factor domain Gly_kinase PF02595.15 EAQ84886.1 - 0.038 13.0 0.0 0.062 12.3 0.0 1.2 1 0 0 1 1 1 0 Glycerate kinase family TFIIA PF03153.13 EAQ84886.1 - 0.53 10.2 10.8 0.95 9.4 10.8 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pectate_lyase_3 PF12708.7 EAQ84888.1 - 1.3e-96 322.6 12.8 2e-83 279.5 4.2 2.9 2 1 0 2 2 2 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 EAQ84888.1 - 6.8e-06 25.7 1.7 0.018 14.7 0.2 3.0 3 0 0 3 3 3 2 N terminal extension of bacteriophage endosialidase Citrate_ly_lig PF08218.11 EAQ84888.1 - 0.047 13.4 0.1 0.088 12.5 0.1 1.3 1 0 0 1 1 1 0 Citrate lyase ligase C-terminal domain AP3D1 PF06375.11 EAQ84889.1 - 0.062 13.5 4.6 0.084 13.1 4.6 1.1 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 NOA36 PF06524.12 EAQ84889.1 - 0.17 11.2 8.9 0.22 10.8 8.9 1.2 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.12 EAQ84889.1 - 0.96 7.6 10.0 1 7.5 10.0 1.0 1 0 0 1 1 1 0 Nop14-like family DUF4820 PF16091.5 EAQ84889.1 - 0.98 8.7 2.8 1.3 8.4 2.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) DNA_pol_phi PF04931.13 EAQ84889.1 - 5.2 5.1 11.5 5.7 4.9 11.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF2461 PF09365.10 EAQ84890.1 - 2e-12 47.5 0.0 2.4e-12 47.3 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical protein (DUF2461) EH_Signature PF15611.6 EAQ84890.1 - 0.1 12.0 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 EH_Signature domain DUF640 PF04852.12 EAQ84891.1 - 0.056 13.6 0.1 0.12 12.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF640) HNH_2 PF13391.6 EAQ84892.1 - 3e-11 43.3 0.2 7.3e-11 42.0 0.2 1.7 1 0 0 1 1 1 1 HNH endonuclease ApbA PF02558.16 EAQ84894.1 - 3.5e-33 114.4 0.0 5.5e-33 113.8 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 EAQ84894.1 - 1.5e-26 93.1 0.0 2.8e-26 92.2 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal Pyr_redox PF00070.27 EAQ84894.1 - 0.11 13.1 0.0 0.2 12.2 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SOG2 PF10428.9 EAQ84894.1 - 0.57 9.3 5.0 0.71 9.0 5.0 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Zn_clus PF00172.18 EAQ84896.1 - 2.2e-10 40.5 13.0 3.2e-10 39.9 13.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EAQ84896.1 - 0.00052 19.1 0.8 0.0054 15.8 0.1 2.3 2 0 0 2 2 2 1 Fungal specific transcription factor domain Lys-AminoMut_A PF09043.11 EAQ84896.1 - 0.026 13.0 0.9 0.053 12.0 0.9 1.4 1 0 0 1 1 1 0 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit FAM184 PF15665.5 EAQ84897.1 - 0.0003 20.7 170.8 0.21 11.4 35.2 7.6 1 1 4 6 6 6 4 Family with sequence similarity 184, A and B TMF_DNA_bd PF12329.8 EAQ84897.1 - 0.0047 16.9 2.9 0.0047 16.9 2.9 14.9 5 4 6 15 15 14 4 TATA element modulatory factor 1 DNA binding DUF3450 PF11932.8 EAQ84897.1 - 0.0054 16.1 9.6 0.0054 16.1 9.6 10.1 2 2 8 10 10 10 1 Protein of unknown function (DUF3450) Spc7 PF08317.11 EAQ84897.1 - 0.28 10.0 174.6 0.23 10.3 21.6 8.5 1 1 8 9 9 9 0 Spc7 kinetochore protein DcpS_C PF11969.8 EAQ84897.1 - 1.5 9.3 5.6 28 5.2 0.2 4.4 3 0 0 3 3 3 0 Scavenger mRNA decapping enzyme C-term binding DUF3861 PF12977.7 EAQ84897.1 - 2 8.6 7.2 8.1 6.7 0.3 4.2 2 1 2 4 4 4 0 Domain of Unknown Function with PDB structure (DUF3861) PKcGMP_CC PF16808.5 EAQ84897.1 - 3.2 7.7 19.0 1.6 8.7 0.4 7.3 6 1 0 6 6 6 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Peptidase_S8 PF00082.22 EAQ84898.1 - 0.039 13.2 0.2 0.086 12.1 0.0 1.6 2 0 0 2 2 2 0 Subtilase family DUF21 PF01595.20 EAQ84899.1 - 5.4e-32 110.9 0.0 9.9e-32 110.0 0.0 1.4 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain LIAS_N PF16881.5 EAQ84899.1 - 0.072 13.5 0.0 0.18 12.2 0.0 1.6 1 0 0 1 1 1 0 N-terminal domain of lipoyl synthase of Radical_SAM family Glyoxalase PF00903.25 EAQ84900.1 - 8.4e-41 139.2 0.1 6.3e-20 71.7 0.0 2.1 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 EAQ84900.1 - 6.1e-16 58.6 0.0 2e-06 28.0 0.0 3.5 2 2 1 3 3 3 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 EAQ84900.1 - 4.2e-08 33.9 0.0 0.0028 18.4 0.0 2.8 2 2 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_3 PF13468.6 EAQ84900.1 - 3.3e-05 24.1 0.0 0.86 9.7 0.0 3.5 1 1 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_2 PF12681.7 EAQ84900.1 - 5.4e-05 23.1 1.0 0.99 9.3 0.0 4.1 4 0 0 4 4 4 1 Glyoxalase-like domain DUF1338 PF07063.13 EAQ84900.1 - 0.012 14.8 0.0 7.9 5.6 0.0 3.5 3 2 1 4 4 4 0 Domain of unknown function (DUF1338) CppA_N PF14506.6 EAQ84900.1 - 0.014 15.5 0.0 0.19 11.8 0.0 2.2 2 0 0 2 2 2 0 CppA N-terminal MoaF PF10703.9 EAQ84900.1 - 0.023 14.6 0.1 2.6 8.0 0.0 2.5 2 0 0 2 2 2 0 MoaF N-terminal domain CppA_C PF14507.6 EAQ84900.1 - 0.1 13.4 0.0 4.8 8.0 0.0 2.2 2 0 0 2 2 2 0 CppA C-terminal DUF4105 PF13387.6 EAQ84900.1 - 0.14 11.8 0.1 38 3.9 0.0 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF4105) 2-Hacid_dh_C PF02826.19 EAQ84901.1 - 6.6e-53 178.7 0.0 1e-52 178.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EAQ84901.1 - 4e-34 117.2 0.1 6.4e-34 116.5 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ACT PF01842.25 EAQ84901.1 - 0.00057 19.6 2.8 0.00094 18.9 0.1 2.6 3 0 0 3 3 3 1 ACT domain XdhC_C PF13478.6 EAQ84901.1 - 0.0031 18.0 0.0 0.0075 16.8 0.0 1.7 1 0 0 1 1 1 1 XdhC Rossmann domain NST1 PF13945.6 EAQ84901.1 - 1.6 8.8 19.6 3.4 7.7 19.6 1.4 1 0 0 1 1 1 0 Salt tolerance down-regulator Menin PF05053.13 EAQ84901.1 - 1.8 6.8 12.3 2.7 6.2 12.3 1.1 1 0 0 1 1 1 0 Menin DUF4770 PF15994.5 EAQ84901.1 - 3.4 7.9 5.5 6.6 6.9 5.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) Presenilin PF01080.17 EAQ84901.1 - 4.8 5.8 5.4 8.3 5.1 5.4 1.3 1 0 0 1 1 1 0 Presenilin Pkinase PF00069.25 EAQ84902.1 - 0.0068 15.8 0.0 0.036 13.4 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Robl_LC7 PF03259.17 EAQ84902.1 - 0.018 14.8 0.2 0.047 13.5 0.2 1.7 1 0 0 1 1 1 0 Roadblock/LC7 domain SPX PF03105.19 EAQ84902.1 - 3.1 7.6 4.7 6.4 6.6 4.7 1.6 1 0 0 1 1 1 0 SPX domain F-box PF00646.33 EAQ84903.1 - 0.054 13.4 0.1 0.15 12.0 0.1 1.8 1 0 0 1 1 1 0 F-box domain Zip PF02535.22 EAQ84904.1 - 3.5e-51 174.4 0.0 5.1e-51 173.9 0.0 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter COX15-CtaA PF02628.15 EAQ84905.1 - 3.1e-113 378.1 7.9 3.6e-113 377.9 7.9 1.0 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein Fumarate_red_C PF02300.17 EAQ84905.1 - 0.13 12.3 1.0 14 5.8 0.1 3.2 3 0 0 3 3 3 0 Fumarate reductase subunit C BHD_3 PF10405.9 EAQ84906.1 - 7.3e-27 93.6 0.0 1.3e-26 92.7 0.0 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_2 PF10404.9 EAQ84906.1 - 0.035 15.1 0.3 0.035 15.1 0.3 4.0 4 2 0 4 4 4 0 Rad4 beta-hairpin domain 2 PTPA PF03095.15 EAQ84907.1 - 2.1e-64 217.8 0.0 3e-64 217.4 0.0 1.2 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Glyco_hydro_92 PF07971.12 EAQ84908.1 - 1.4e-90 304.5 0.5 1.9e-69 234.8 0.0 2.1 1 1 1 2 2 2 2 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 EAQ84908.1 - 6.6e-62 209.5 0.6 1e-61 208.9 0.6 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain Zn_clus PF00172.18 EAQ84909.1 - 1.8e-08 34.4 6.2 3.9e-08 33.3 6.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EAQ84909.1 - 0.00011 21.2 0.0 0.00015 20.7 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain RTA1 PF04479.13 EAQ84910.1 - 1.1e-33 116.6 0.0 2.7e-33 115.3 0.0 1.7 1 1 0 1 1 1 1 RTA1 like protein HECT PF00632.25 EAQ84911.1 - 1.5e-83 280.8 0.0 2e-83 280.4 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.27 EAQ84911.1 - 0.0016 18.1 2.8 0.0047 16.6 2.8 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif RRM_1 PF00076.22 EAQ84912.1 - 1.8e-83 274.4 3.5 9.9e-22 76.5 0.1 5.3 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 EAQ84912.1 - 2.3e-27 95.0 1.5 7e-27 93.4 1.5 1.9 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.6 EAQ84912.1 - 1.8e-10 40.5 0.0 0.0039 16.8 0.0 5.1 2 1 2 5 5 5 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EAQ84912.1 - 2e-07 30.7 0.0 0.0027 17.5 0.0 3.9 4 0 0 4 4 4 2 Occluded RNA-recognition motif RRM_7 PF16367.5 EAQ84912.1 - 1.1e-05 25.4 0.2 0.41 10.8 0.0 4.9 4 1 0 4 4 4 1 RNA recognition motif YflT PF11181.8 EAQ84912.1 - 0.0013 19.2 6.4 0.058 13.9 0.2 3.4 3 0 0 3 3 3 1 Heat induced stress protein YflT Nup35_RRM_2 PF14605.6 EAQ84912.1 - 0.0013 18.6 0.7 13 5.9 0.0 4.3 4 1 0 4 4 4 1 Nup53/35/40-type RNA recognition motif CbiG_mid PF11761.8 EAQ84912.1 - 0.028 14.5 0.2 18 5.5 0.0 3.6 4 0 0 4 4 4 0 Cobalamin biosynthesis central region OB_RNB PF08206.11 EAQ84912.1 - 0.088 12.5 1.8 11 5.8 0.0 3.5 3 0 0 3 3 3 0 Ribonuclease B OB domain Nefa_Nip30_N PF10187.9 EAQ84912.1 - 0.14 12.6 0.2 0.14 12.6 0.2 3.8 4 0 0 4 4 3 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 DUF3408 PF11888.8 EAQ84912.1 - 2.1 8.5 9.4 0.15 12.2 2.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) Usp PF00582.26 EAQ84914.1 - 1e-22 81.1 4.5 8.2e-15 55.6 0.1 3.2 3 0 0 3 3 3 2 Universal stress protein family Ribosomal_S7 PF00177.21 EAQ84915.1 - 2.2e-26 92.3 0.0 3.1e-26 91.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e NMO PF03060.15 EAQ84916.1 - 3.3e-53 181.2 0.0 2.6e-52 178.3 0.0 1.9 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 EAQ84916.1 - 4.2e-08 32.6 0.0 4.9e-06 25.8 0.0 2.1 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 EAQ84916.1 - 0.00034 19.7 0.2 0.00084 18.5 0.2 1.6 2 0 0 2 2 2 1 FMN-dependent dehydrogenase NanE PF04131.14 EAQ84916.1 - 0.13 11.5 0.0 0.13 11.5 0.0 1.7 2 0 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase PEX11 PF05648.14 EAQ84917.1 - 2.8e-74 249.4 0.8 3.1e-74 249.2 0.8 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) NS3 PF17530.2 EAQ84919.1 - 0.037 13.6 0.1 0.045 13.3 0.1 1.1 1 0 0 1 1 1 0 Non-structural protein NS3 Chal_sti_synt_N PF00195.19 EAQ84920.1 - 1.4e-18 67.2 0.1 1.9e-18 66.7 0.1 1.1 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain Chal_sti_synt_C PF02797.15 EAQ84920.1 - 4e-05 23.6 0.0 7.7e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain FAE1_CUT1_RppA PF08392.12 EAQ84920.1 - 7.4e-05 22.2 0.1 9.4e-05 21.8 0.1 1.1 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein Sugar_tr PF00083.24 EAQ84921.1 - 1.3e-27 96.8 31.8 1.9e-18 66.6 10.7 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EAQ84921.1 - 1.2e-15 57.3 48.8 5.8e-12 45.2 24.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily p450 PF00067.22 EAQ84922.1 - 1.6e-39 135.9 0.0 4e-39 134.7 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.7 EAQ84923.1 - 1.9e-05 24.4 0.3 1.9e-05 24.4 0.3 2.4 2 0 0 2 2 2 1 F-box-like Nucleoporin_N PF08801.11 EAQ84923.1 - 0.0057 15.5 0.0 0.0086 14.9 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like F-box PF00646.33 EAQ84923.1 - 0.007 16.2 1.7 0.008 16.0 0.2 2.0 2 0 0 2 2 2 1 F-box domain FBPase PF00316.20 EAQ84924.1 - 1.9e-71 239.4 0.2 2.6e-71 239.0 0.2 1.2 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain NdhM PF10664.9 EAQ84924.1 - 0.073 13.3 0.0 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 Cyanobacterial and plastid NDH-1 subunit M Thiolase_N PF00108.23 EAQ84925.1 - 4.7e-72 242.5 5.9 6.1e-72 242.1 5.9 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EAQ84925.1 - 6.5e-37 125.9 0.0 1.5e-36 124.7 0.0 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EAQ84925.1 - 0.031 13.8 0.3 0.031 13.8 0.3 2.1 3 0 0 3 3 3 0 Beta-ketoacyl synthase, N-terminal domain Tudor_3 PF18115.1 EAQ84927.1 - 1.4e-06 28.1 0.0 2.2e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain DUF4537 PF15057.6 EAQ84927.1 - 0.012 15.7 0.0 0.02 14.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4537) LBR_tudor PF09465.10 EAQ84927.1 - 0.025 14.4 0.0 0.043 13.6 0.0 1.4 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain DUF1325 PF07039.11 EAQ84927.1 - 0.039 14.0 0.1 0.094 12.8 0.1 1.6 1 0 0 1 1 1 0 SGF29 tudor-like domain IL11 PF07400.11 EAQ84927.1 - 0.048 13.3 0.3 0.075 12.7 0.3 1.3 1 0 0 1 1 1 0 Interleukin 11 Herpes_capsid PF06112.11 EAQ84927.1 - 0.084 12.9 3.6 0.15 12.1 3.6 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Fis1_TPR_C PF14853.6 EAQ84927.1 - 0.2 11.7 0.4 0.45 10.6 0.4 1.5 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat ParA PF10609.9 EAQ84928.1 - 2.2e-37 128.8 0.0 9.7e-37 126.7 0.0 1.7 2 0 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 EAQ84928.1 - 3.8e-07 30.2 0.0 4.3e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 EAQ84928.1 - 1.2e-05 25.3 0.0 1.7e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain MipZ PF09140.11 EAQ84928.1 - 0.00074 18.9 0.0 0.00093 18.6 0.0 1.1 1 0 0 1 1 1 1 ATPase MipZ AAA_25 PF13481.6 EAQ84928.1 - 0.0069 16.0 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain CBP_BcsQ PF06564.12 EAQ84928.1 - 0.011 15.2 0.0 0.017 14.6 0.0 1.3 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsQ CLP1_P PF16575.5 EAQ84928.1 - 0.039 13.8 0.0 0.052 13.3 0.0 1.2 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop ArsA_ATPase PF02374.15 EAQ84928.1 - 0.074 12.2 0.0 0.097 11.8 0.0 1.1 1 0 0 1 1 1 0 Anion-transporting ATPase MeaB PF03308.16 EAQ84928.1 - 0.12 11.3 0.1 0.16 10.9 0.1 1.1 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB TRAUB PF08164.12 EAQ84929.1 - 1.1e-30 106.0 0.1 5.5e-30 103.7 0.1 2.3 1 0 0 1 1 1 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.6 EAQ84929.1 - 1e-26 94.2 0.2 1e-26 94.2 0.2 3.3 4 0 0 4 4 4 1 Apoptosis antagonizing transcription factor HutP PF09021.11 EAQ84929.1 - 0.16 12.3 1.7 0.58 10.5 1.7 2.0 2 1 0 2 2 2 0 HutP Pro_CA PF00484.19 EAQ84930.1 - 8.8e-47 159.3 0.6 1e-46 159.0 0.6 1.1 1 0 0 1 1 1 1 Carbonic anhydrase Ribosomal_L7Ae PF01248.26 EAQ84931.1 - 3.1e-21 74.9 0.7 5.6e-21 74.1 0.7 1.5 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family CLPTM1 PF05602.12 EAQ84931.1 - 0.032 13.2 0.3 0.04 12.9 0.3 1.1 1 0 0 1 1 1 0 Cleft lip and palate transmembrane protein 1 (CLPTM1) zn-ribbon_14 PF16503.5 EAQ84932.1 - 1.7e-18 65.8 4.3 1.7e-18 65.8 4.3 3.3 3 0 0 3 3 3 1 Zinc-ribbon ATP_bind_3 PF01171.20 EAQ84932.1 - 6.9e-18 65.0 0.0 1.1e-17 64.4 0.0 1.3 1 0 0 1 1 1 1 PP-loop family tRNA_Me_trans PF03054.16 EAQ84932.1 - 0.019 13.8 0.0 0.032 13.0 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase RecR PF02132.15 EAQ84932.1 - 0.03 13.9 9.4 0.038 13.6 2.0 3.1 3 0 0 3 3 3 0 RecR protein MOZ_SAS PF01853.18 EAQ84933.1 - 4.6e-75 251.2 0.0 6.4e-75 250.7 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 EAQ84933.1 - 6.7e-21 73.6 3.4 1.5e-20 72.6 3.4 1.6 1 0 0 1 1 1 1 MYST family zinc finger domain Acetyltransf_7 PF13508.7 EAQ84933.1 - 0.13 12.7 0.0 0.31 11.5 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PHD_4 PF16866.5 EAQ84933.1 - 0.98 9.6 9.7 0.66 10.1 1.2 2.9 1 1 1 2 2 2 0 PHD-finger Rubredoxin PF00301.20 EAQ84933.1 - 1.9 8.6 7.5 6.6 6.9 7.5 1.9 1 0 0 1 1 1 0 Rubredoxin ENTH PF01417.20 EAQ84934.1 - 7.5e-38 129.4 0.6 1.3e-37 128.6 0.6 1.4 1 0 0 1 1 1 1 ENTH domain DUF1720 PF08226.11 EAQ84934.1 - 2.9e-07 30.8 45.1 2.9e-07 30.8 45.1 5.9 1 1 2 3 3 3 1 Domain of unknown function (DUF1720) UIM PF02809.20 EAQ84934.1 - 0.0052 16.6 6.6 0.0073 16.2 0.6 2.8 2 0 0 2 2 2 1 Ubiquitin interaction motif DUF4264 PF14084.6 EAQ84934.1 - 0.022 14.4 0.0 0.04 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4264) Nup96 PF12110.8 EAQ84935.1 - 5.5e-58 196.4 0.4 2.7e-56 190.8 0.4 2.3 1 1 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.14 EAQ84935.1 - 2.2e-47 160.9 0.0 3.6e-47 160.2 0.0 1.3 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.6 EAQ84935.1 - 2.9e-18 66.5 174.9 1.2e-06 29.2 34.4 10.9 3 2 7 10 10 10 4 Nucleoporin FG repeat region Hamartin PF04388.12 EAQ84935.1 - 6.6 5.3 4.7 9.9 4.7 4.7 1.1 1 0 0 1 1 1 0 Hamartin protein UCH_1 PF13423.6 EAQ84938.1 - 7.3e-68 229.5 0.0 4.4e-67 226.9 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.24 EAQ84938.1 - 1.3e-21 77.8 0.0 2.2e-21 77.1 0.0 1.4 1 0 0 1 1 1 1 Exonuclease UCH PF00443.29 EAQ84938.1 - 0.00023 20.7 0.0 0.021 14.3 0.0 2.2 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Ima1_N PF09779.9 EAQ84938.1 - 0.15 13.0 0.0 1.3 9.9 0.1 2.3 2 0 0 2 2 2 0 Ima1 N-terminal domain SHNi-TPR PF10516.9 EAQ84938.1 - 0.2 11.2 0.1 0.37 10.3 0.1 1.4 1 0 0 1 1 1 0 SHNi-TPR Mito_carr PF00153.27 EAQ84939.1 - 2.3e-51 171.7 3.3 3.8e-16 58.8 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein adh_short PF00106.25 EAQ84940.1 - 1.1e-33 116.3 0.0 1.8e-33 115.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EAQ84940.1 - 4.2e-33 114.8 0.1 2e-32 112.6 0.1 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EAQ84940.1 - 2.6e-08 34.0 0.6 2.6e-08 34.0 0.6 1.5 2 0 0 2 2 2 1 KR domain GTP_EFTU PF00009.27 EAQ84941.1 - 7.5e-42 143.1 0.1 1.3e-41 142.3 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EAQ84941.1 - 3.5e-28 98.2 0.0 1.2e-27 96.4 0.0 2.0 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EAQ84941.1 - 2e-08 34.5 0.8 6e-08 33.0 0.8 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EAQ84941.1 - 0.0014 18.7 0.1 0.0096 16.0 0.1 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase TonB_N PF16031.5 EAQ84941.1 - 0.63 10.5 19.0 1.3 9.5 19.0 1.4 1 0 0 1 1 1 0 TonB polyproline region Mitofilin PF09731.9 EAQ84941.1 - 1.6 7.5 11.8 2.3 7.0 11.8 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Ran-binding PF05508.11 EAQ84942.1 - 5.6e-118 393.5 0.0 1.1e-117 392.5 0.0 1.5 2 0 0 2 2 2 1 RanGTP-binding protein MFS_1 PF07690.16 EAQ84943.1 - 5.3e-29 101.2 45.3 7.5e-29 100.7 44.1 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 EAQ84943.1 - 0.00093 18.6 6.8 0.00093 18.6 6.8 2.3 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB SieB PF14163.6 EAQ84943.1 - 0.13 11.8 0.2 0.36 10.3 0.0 1.9 2 0 0 2 2 2 0 Super-infection exclusion protein B DUF2929 PF11151.8 EAQ84943.1 - 4.8 7.5 11.2 3.9 7.8 0.1 4.3 4 0 0 4 4 4 0 Protein of unknown function (DUF2929) zf-RVT PF13966.6 EAQ84945.1 - 0.017 15.8 0.1 0.063 14.0 0.0 1.9 2 0 0 2 2 2 0 zinc-binding in reverse transcriptase SNF2_N PF00176.23 EAQ84946.1 - 2.5e-70 237.0 0.2 7.1e-66 222.3 0.0 2.2 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 EAQ84946.1 - 1.4e-15 57.6 0.0 6.3e-15 55.5 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EAQ84946.1 - 3.7e-06 27.0 0.0 8.2e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Surp PF01805.20 EAQ84951.1 - 1.4e-11 44.2 0.0 3.4e-11 42.9 0.0 1.7 2 0 0 2 2 2 1 Surp module DAO PF01266.24 EAQ84952.1 - 1.8e-25 90.3 0.1 2.2e-25 90.0 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EAQ84952.1 - 0.0018 18.3 0.3 0.0041 17.1 0.3 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding GIDA PF01134.22 EAQ84952.1 - 0.0028 16.8 0.0 0.0039 16.3 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 EAQ84952.1 - 0.019 14.1 0.1 0.034 13.2 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_2 PF07992.14 EAQ84952.1 - 0.028 13.6 0.0 0.042 13.1 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TBP PF00352.21 EAQ84953.1 - 7e-31 106.0 0.0 7.7e-31 105.9 0.0 1.0 1 0 0 1 1 1 1 Transcription factor TFIID (or TATA-binding protein, TBP) Pax7 PF12360.8 EAQ84953.1 - 0.19 12.0 0.1 0.26 11.5 0.1 1.2 1 0 0 1 1 1 0 Paired box protein 7 ETF_QO PF05187.13 EAQ84955.1 - 1.1e-48 163.6 0.4 1.9e-48 162.9 0.4 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S NAD_binding_8 PF13450.6 EAQ84955.1 - 1.1e-07 32.0 0.0 5.9e-07 29.6 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EAQ84955.1 - 5.4e-07 29.5 0.0 0.00011 21.9 0.0 2.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EAQ84955.1 - 1.9e-05 24.0 0.0 5.4e-05 22.6 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EAQ84955.1 - 0.00016 21.0 0.0 0.0044 16.3 0.0 2.1 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 EAQ84955.1 - 0.00021 20.1 0.3 0.00031 19.6 0.3 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.7 EAQ84955.1 - 0.00023 20.6 0.0 0.00037 20.0 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EAQ84955.1 - 0.00064 19.1 0.0 0.0011 18.2 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 EAQ84955.1 - 0.0011 18.2 0.6 0.004 16.3 0.7 1.8 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.6 EAQ84955.1 - 0.0015 18.6 0.1 0.006 16.6 0.1 1.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding Trp_halogenase PF04820.14 EAQ84955.1 - 0.0015 17.5 0.0 0.34 9.7 0.1 2.2 1 1 1 2 2 2 2 Tryptophan halogenase Fer4_7 PF12838.7 EAQ84955.1 - 0.0074 16.9 1.1 0.022 15.3 1.1 1.8 1 0 0 1 1 1 1 4Fe-4S dicluster domain Pyr_redox PF00070.27 EAQ84955.1 - 0.0085 16.6 0.1 6.7 7.4 0.2 2.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EAQ84955.1 - 0.0087 15.4 0.3 0.013 14.8 0.3 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EAQ84955.1 - 0.011 15.1 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 EAQ84955.1 - 0.033 13.2 0.2 0.053 12.6 0.2 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.22 EAQ84955.1 - 0.094 11.8 0.4 0.14 11.2 0.4 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Fer4_2 PF12797.7 EAQ84955.1 - 0.15 12.2 0.7 0.44 10.7 0.7 1.8 1 0 0 1 1 1 0 4Fe-4S binding domain CorA PF01544.18 EAQ84956.1 - 6.5e-12 45.4 4.0 6.5e-12 45.4 4.0 2.2 2 1 0 2 2 2 1 CorA-like Mg2+ transporter protein LXG PF04740.12 EAQ84956.1 - 0.82 9.3 11.4 0.086 12.5 4.4 2.8 3 1 1 4 4 4 0 LXG domain of WXG superfamily DUF2232 PF09991.9 EAQ84956.1 - 1.1 8.4 4.0 0.92 8.6 2.1 1.7 1 1 1 2 2 2 0 Predicted membrane protein (DUF2232) Not1 PF04054.15 EAQ84957.1 - 1.6e-116 389.2 0.0 5.9e-116 387.4 0.0 2.0 2 0 0 2 2 2 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 EAQ84957.1 - 7.6e-91 303.5 3.7 1.5e-90 302.5 3.7 1.5 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain DUF3819 PF12842.7 EAQ84957.1 - 7.1e-48 162.3 1.5 7.1e-48 162.3 1.5 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3819) CNOT1_TTP_bind PF16417.5 EAQ84957.1 - 3.5e-43 147.0 0.1 1.6e-42 144.8 0.0 2.1 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 TTP binding domain CNOT1_HEAT PF16418.5 EAQ84957.1 - 2e-40 138.3 1.4 4e-40 137.3 0.1 2.3 3 0 0 3 3 3 1 CCR4-NOT transcription complex subunit 1 HEAT repeat Methyltransf_23 PF13489.6 EAQ84959.1 - 2.1e-15 56.9 0.0 4.2e-15 56.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAQ84959.1 - 0.0012 19.5 0.0 0.47 11.2 0.0 3.2 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 EAQ84959.1 - 0.0018 18.9 0.0 8.8 7.1 0.0 3.2 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_12 PF08242.12 EAQ84959.1 - 0.0023 18.6 0.0 3 8.6 0.0 2.8 3 0 0 3 3 3 2 Methyltransferase domain UPF0029 PF01205.19 EAQ84960.1 - 5.3e-25 87.8 0.0 1.1e-24 86.8 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 PASTA PF03793.19 EAQ84960.1 - 0.054 13.3 0.2 0.14 12.0 0.2 1.8 1 0 0 1 1 1 0 PASTA domain FCH PF00611.23 EAQ84961.1 - 2e-16 60.0 0.0 4.7e-16 58.8 0.0 1.7 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.28 EAQ84961.1 - 2.8e-13 49.3 0.0 5.4e-13 48.3 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EAQ84961.1 - 5.4e-12 45.2 0.0 9.8e-11 41.2 0.0 2.5 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.6 EAQ84961.1 - 7.6e-11 41.7 0.1 1.5e-10 40.7 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain Seipin PF06775.14 EAQ84962.1 - 4.1e-40 138.0 0.0 6.1e-40 137.4 0.0 1.2 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) MPP6 PF10175.9 EAQ84962.1 - 0.31 11.5 0.1 0.31 11.5 0.1 2.1 2 0 0 2 2 2 0 M-phase phosphoprotein 6 NTF2 PF02136.20 EAQ84963.1 - 2e-16 60.7 0.0 3.7e-16 59.8 0.0 1.4 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Cwf_Cwc_15 PF04889.12 EAQ84963.1 - 0.02 14.7 15.5 0.013 15.3 6.4 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein EthD PF07110.11 EAQ84964.1 - 7.2e-18 65.5 0.0 6.4e-17 62.5 0.0 2.1 1 1 0 1 1 1 1 EthD domain HTH_51 PF18558.1 EAQ84965.1 - 9.7e-19 67.0 0.0 1.7e-18 66.3 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain Methyltransf_12 PF08242.12 EAQ84965.1 - 2.4e-06 28.2 0.0 1.1e-05 26.1 0.0 2.1 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAQ84965.1 - 4.6e-05 24.0 0.0 0.00011 22.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_33 PF10017.9 EAQ84965.1 - 0.043 13.0 0.0 0.07 12.3 0.0 1.3 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent Cg6151-P PF10233.9 EAQ84966.1 - 3.5e-41 140.0 14.2 4.4e-41 139.8 14.2 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P YIF1 PF03878.15 EAQ84966.1 - 0.039 13.5 0.6 0.048 13.2 0.6 1.0 1 0 0 1 1 1 0 YIF1 Trp_oprn_chp PF09534.10 EAQ84966.1 - 0.084 12.7 3.9 0.14 12.0 3.9 1.3 1 1 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) COPI_assoc PF08507.10 EAQ84966.1 - 0.96 9.5 11.2 1.6 8.8 11.3 1.3 1 1 0 1 1 1 0 COPI associated protein Aim21 PF11489.8 EAQ84967.1 - 1.8e-246 820.6 85.0 1.8e-246 820.6 85.0 2.5 3 0 0 3 3 3 1 Altered inheritance of mitochondria protein 21 Gryzun PF07919.12 EAQ84968.1 - 2.5e-190 634.2 0.0 2.2e-175 584.8 0.0 2.1 2 0 0 2 2 2 2 Gryzun, putative trafficking through Golgi Foie-gras_1 PF11817.8 EAQ84968.1 - 2.7e-99 331.9 1.9 5.1e-94 314.7 3.5 2.1 2 0 0 2 2 2 2 Foie gras liver health family 1 Gryzun-like PF12742.7 EAQ84968.1 - 0.049 13.6 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 Gryzun, putative Golgi trafficking AAA_12 PF13087.6 EAQ84969.1 - 5.1e-51 173.1 0.0 8.8e-51 172.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain Dna2 PF08696.11 EAQ84969.1 - 1.3e-29 103.5 0.3 1e-24 87.5 0.1 2.6 1 1 1 2 2 2 2 DNA replication factor Dna2 AAA_11 PF13086.6 EAQ84969.1 - 7.6e-22 78.3 0.0 4.5e-17 62.7 0.0 2.6 1 1 1 2 2 2 2 AAA domain Cas_Cas4 PF01930.17 EAQ84969.1 - 0.00016 21.8 0.0 0.00045 20.3 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function DUF83 Viral_helicase1 PF01443.18 EAQ84969.1 - 0.001 18.9 0.1 1.1 9.0 0.0 2.5 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 EAQ84969.1 - 0.055 13.2 0.0 0.18 11.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 EAQ84969.1 - 0.07 13.5 0.0 0.23 11.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain zf-primase PF09329.11 EAQ84970.1 - 7.2e-19 67.3 1.8 1.2e-18 66.6 1.8 1.4 1 0 0 1 1 1 1 Primase zinc finger tRNA_anti-codon PF01336.25 EAQ84970.1 - 0.012 15.5 0.0 0.021 14.8 0.0 1.4 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain CALM_bind PF16025.5 EAQ84970.1 - 4.4 7.8 6.3 1.4 9.4 0.3 2.8 2 1 0 2 2 2 0 Calcium-dependent calmodulin binding RNase_H2-Ydr279 PF09468.10 EAQ84971.1 - 7.5e-35 120.5 0.0 1.2e-34 119.8 0.0 1.4 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) wHTH domain Ydr279_N PF17745.1 EAQ84971.1 - 1.1e-21 76.9 3.6 1.5e-21 76.5 0.3 2.4 2 0 0 2 2 2 1 Ydr279p protein triple barrel domain DASH_Duo1 PF08651.10 EAQ84972.1 - 6.5e-33 112.3 0.2 9.6e-33 111.8 0.2 1.3 1 0 0 1 1 1 1 DASH complex subunit Duo1 DUF1682 PF07946.14 EAQ84972.1 - 0.0051 16.1 2.7 0.0069 15.6 2.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) DASH_Dad2 PF08654.10 EAQ84972.1 - 0.065 13.7 3.5 0.13 12.7 3.5 1.6 1 1 0 1 1 1 0 DASH complex subunit Dad2 Rrn6 PF10214.9 EAQ84972.1 - 0.13 10.7 5.6 0.15 10.5 5.6 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor API5 PF05918.11 EAQ84972.1 - 0.29 9.9 3.3 0.36 9.6 3.3 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) DUF4337 PF14235.6 EAQ84972.1 - 1.8 8.7 4.2 2.9 8.0 4.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) MCU PF04678.13 EAQ84972.1 - 2.1 8.4 6.3 6.5 6.8 6.1 1.7 1 1 1 2 2 2 0 Mitochondrial calcium uniporter TTL PF03133.15 EAQ84974.1 - 3.3e-50 170.9 0.0 5.3e-50 170.2 0.0 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family SurE PF01975.17 EAQ84974.1 - 4e-49 167.1 0.0 2.1e-48 164.7 0.0 2.0 2 0 0 2 2 2 1 Survival protein SurE ATPgrasp_YheCD PF14398.6 EAQ84974.1 - 0.013 14.8 0.0 0.064 12.5 0.0 2.0 2 1 0 2 2 2 0 YheC/D like ATP-grasp Glyco_trans_4_4 PF13579.6 EAQ84974.1 - 0.032 14.7 0.1 0.12 12.8 0.1 2.0 2 0 0 2 2 2 0 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 EAQ84974.1 - 0.073 13.1 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase Family 4 LigB PF02900.18 EAQ84975.1 - 0.22 10.5 0.0 0.25 10.4 0.0 1.0 1 0 0 1 1 1 0 Catalytic LigB subunit of aromatic ring-opening dioxygenase E1-E2_ATPase PF00122.20 EAQ84976.1 - 2.9e-34 118.2 1.8 2.9e-34 118.2 1.8 2.7 3 1 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 EAQ84976.1 - 3.7e-22 78.2 0.0 7.9e-22 77.2 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EAQ84976.1 - 5.7e-22 79.0 0.0 1.5e-21 77.6 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.21 EAQ84976.1 - 8.4e-08 32.1 0.4 8.4e-08 32.1 0.4 2.9 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase_3 PF08282.12 EAQ84976.1 - 9.7e-07 28.8 0.7 5.4e-06 26.3 0.8 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EAQ84976.1 - 5.2e-06 26.1 1.2 0.00032 20.3 0.0 3.3 3 0 0 3 3 3 1 Cation transporter/ATPase, N-terminus HAD PF12710.7 EAQ84976.1 - 0.00028 21.4 0.0 0.00058 20.3 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF2976 PF11190.8 EAQ84976.1 - 0.00033 20.4 7.2 0.11 12.4 0.2 3.4 3 0 0 3 3 3 2 Protein of unknown function (DUF2976) LptF_LptG PF03739.14 EAQ84976.1 - 0.00057 18.8 2.8 0.0013 17.7 2.8 1.5 1 0 0 1 1 1 1 Lipopolysaccharide export system permease LptF/LptG Cortexin PF11057.8 EAQ84976.1 - 0.011 15.6 0.2 6.6 6.7 0.0 2.8 2 0 0 2 2 2 0 Cortexin of kidney Transposase_20 PF02371.16 EAQ84976.1 - 0.097 13.0 0.0 0.29 11.5 0.0 1.8 1 0 0 1 1 1 0 Transposase IS116/IS110/IS902 family DUF3500 PF12006.8 EAQ84976.1 - 0.21 11.1 0.0 0.47 9.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3500) DUF4231 PF14015.6 EAQ84976.1 - 9 6.8 9.0 11 6.5 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) Cation_ATPase_C PF00689.21 EAQ84977.1 - 1.6e-05 24.7 1.4 3e-05 23.8 1.4 1.5 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus SfLAP PF11139.8 EAQ84977.1 - 0.047 13.1 0.1 0.077 12.4 0.1 1.4 1 1 0 1 1 1 0 Sap, sulfolipid-1-addressing protein SIR2 PF02146.17 EAQ84978.1 - 4.9e-58 196.0 0.0 7e-58 195.4 0.0 1.2 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.13 EAQ84978.1 - 4.2e-05 23.4 0.0 7.5e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.22 EAQ84978.1 - 0.00085 19.1 0.1 0.59 9.9 0.0 2.3 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain DNA_RNApol_7kD PF03604.13 EAQ84978.1 - 0.23 11.2 2.2 9 6.1 0.2 2.4 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit Pkinase PF00069.25 EAQ84979.1 - 2.5e-10 40.2 0.0 6.3e-07 29.0 0.0 2.7 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ84979.1 - 0.0024 17.2 0.0 1.5 8.1 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase NRIP1_repr_3 PF15689.5 EAQ84979.1 - 0.12 12.7 2.0 0.43 10.9 2.0 2.1 1 0 0 1 1 1 0 Nuclear receptor-interacting protein 1 repression 3 DUF4805 PF16063.5 EAQ84979.1 - 0.37 10.1 4.9 0.78 9.0 4.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4805) Aminotran_4 PF01063.19 EAQ84980.1 - 7.7e-34 117.5 0.0 9.7e-34 117.2 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV ESSS PF10183.9 EAQ84981.1 - 5.3e-15 55.5 0.2 6.2e-15 55.3 0.2 1.2 1 1 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Piwi PF02171.17 EAQ84982.1 - 3.6e-73 246.4 0.0 5.6e-73 245.8 0.0 1.2 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 EAQ84982.1 - 3.7e-13 50.3 0.0 6.9e-13 49.4 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 EAQ84982.1 - 6.9e-13 48.1 0.1 1.6e-12 46.9 0.1 1.6 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoL2 PF16488.5 EAQ84982.1 - 2.1e-08 34.4 0.0 5.5e-08 33.0 0.0 1.7 1 0 0 1 1 1 1 Argonaute linker 2 domain ArgoMid PF16487.5 EAQ84982.1 - 0.02 15.1 0.0 0.041 14.1 0.0 1.6 1 0 0 1 1 1 0 Mid domain of argonaute PEMT PF04191.13 EAQ84983.1 - 5.5e-31 107.1 3.2 8.2e-31 106.6 3.2 1.3 1 0 0 1 1 1 1 Phospholipid methyltransferase Steroid_dh PF02544.16 EAQ84983.1 - 0.15 12.0 0.6 0.41 10.6 0.2 1.8 1 1 0 2 2 2 0 3-oxo-5-alpha-steroid 4-dehydrogenase HRG PF16954.5 EAQ84983.1 - 0.15 12.4 3.3 14 6.2 0.1 2.9 3 1 0 3 3 3 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene Spermine_synth PF01564.17 EAQ84984.1 - 2.8e-07 30.2 0.0 4.7e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Methyltransf_23 PF13489.6 EAQ84984.1 - 0.00024 21.0 0.0 0.00085 19.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EAQ84984.1 - 0.015 16.0 0.0 0.033 14.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_30 PF05430.11 EAQ84984.1 - 0.13 12.2 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase Pyridox_ox_2 PF12900.7 EAQ84985.1 - 6.4e-26 91.0 0.0 9.8e-26 90.4 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyr_redox_2 PF07992.14 EAQ84987.1 - 1.3e-50 172.3 1.6 2e-50 171.7 1.6 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NIR_SIR PF01077.22 EAQ84987.1 - 1.5e-18 66.9 0.1 5e-18 65.1 0.0 2.0 2 0 0 2 2 2 1 Nitrite and sulphite reductase 4Fe-4S domain Pyr_redox PF00070.27 EAQ84987.1 - 3.8e-17 62.6 4.0 3.8e-15 56.2 0.8 2.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Fer2_BFD PF04324.15 EAQ84987.1 - 2.8e-15 56.4 5.0 7.8e-12 45.4 6.1 2.6 2 0 0 2 2 2 2 BFD-like [2Fe-2S] binding domain Rieske_2 PF13806.6 EAQ84987.1 - 1.5e-13 50.5 0.0 4.3e-13 49.1 0.0 1.8 2 0 0 2 2 1 1 Rieske-like [2Fe-2S] domain NIR_SIR_ferr PF03460.17 EAQ84987.1 - 3.1e-10 39.7 0.0 6.4e-10 38.7 0.0 1.6 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Rieske PF00355.26 EAQ84987.1 - 4.7e-07 29.7 0.1 7.5e-06 25.8 0.0 2.8 3 0 0 3 3 3 1 Rieske [2Fe-2S] domain Rubredoxin_C PF18267.1 EAQ84987.1 - 2e-05 24.4 0.5 0.026 14.4 0.1 3.5 4 0 0 4 4 4 2 Rubredoxin NAD+ reductase C-terminal domain NAD_binding_9 PF13454.6 EAQ84987.1 - 0.00028 20.9 1.4 0.72 9.8 0.1 3.7 3 1 1 4 4 4 1 FAD-NAD(P)-binding NAD_binding_7 PF13241.6 EAQ84987.1 - 0.0099 16.3 0.7 0.12 12.8 0.0 2.4 2 0 0 2 2 2 1 Putative NAD(P)-binding K_oxygenase PF13434.6 EAQ84987.1 - 0.023 13.9 0.0 0.14 11.2 0.0 2.1 1 1 1 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.21 EAQ84987.1 - 0.092 12.0 3.6 2.4 7.4 0.0 2.8 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 EAQ84987.1 - 1.4 8.4 4.8 54 3.2 0.1 3.9 3 1 0 4 4 4 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EAQ84987.1 - 2.5 7.1 5.6 1 8.4 0.1 2.6 2 1 0 3 3 3 0 FAD binding domain Na_H_Exchanger PF00999.21 EAQ84988.1 - 3.5e-45 154.4 39.7 2.5e-43 148.3 39.7 2.1 1 1 0 1 1 1 1 Sodium/hydrogen exchanger family U71 PF17474.2 EAQ84989.1 - 0.024 14.6 12.9 3.4 7.7 0.0 6.7 7 0 0 7 7 7 0 Tegument protein UL11 homolog DUF824 PF05688.11 EAQ84989.1 - 0.05 13.4 35.4 6.3 6.7 0.4 7.6 7 0 0 7 7 7 0 Salmonella repeat of unknown function (DUF824) Peptidase_S8 PF00082.22 EAQ84991.1 - 1.7e-08 34.1 0.4 4.4e-08 32.7 0.4 1.7 1 1 0 1 1 1 1 Subtilase family Rcd1 PF04078.13 EAQ84993.1 - 7.7e-70 235.1 3.2 9.3e-62 208.6 0.5 2.1 1 1 1 2 2 2 2 Cell differentiation family, Rcd1-like Opi1 PF08618.10 EAQ84993.1 - 0.084 12.1 2.2 0.12 11.6 2.2 1.1 1 0 0 1 1 1 0 Transcription factor Opi1 RuvC_III PF18541.1 EAQ84993.1 - 0.93 9.4 5.9 1.5 8.7 5.9 1.3 1 0 0 1 1 1 0 RuvC endonuclease subdomain 3 Ceramidase_alk PF04734.13 EAQ84994.1 - 2.2e-211 702.9 0.0 8e-211 701.1 0.0 1.7 1 1 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 EAQ84994.1 - 3.8e-20 72.4 1.4 4.3e-16 59.3 0.3 2.3 1 1 1 2 2 2 2 Neutral/alkaline non-lysosomal ceramidase, C-terminal Amidohydro_1 PF01979.20 EAQ84995.1 - 0.0073 15.7 0.0 0.011 15.1 0.0 1.2 1 1 0 1 1 1 1 Amidohydrolase family Glyco_hydro_3 PF00933.21 EAQ84996.1 - 1.5e-56 192.1 0.0 1.8e-56 191.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Hexokinase_1 PF00349.21 EAQ84998.1 - 1e-21 77.8 0.0 1.6e-21 77.1 0.0 1.3 1 0 0 1 1 1 1 Hexokinase DUF2014 PF09427.10 EAQ84999.1 - 2.1e-113 378.0 2.9 3.3e-113 377.4 2.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2014) HLH PF00010.26 EAQ84999.1 - 5.4e-06 26.3 2.7 6e-05 22.9 0.1 2.5 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Nnf1 PF03980.14 EAQ84999.1 - 0.027 14.9 1.9 3.5 8.0 1.2 3.0 3 0 0 3 3 3 0 Nnf1 Spt5_N PF11942.8 EAQ84999.1 - 0.069 14.1 6.2 0.13 13.3 6.2 1.4 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal DTHCT PF08070.11 EAQ84999.1 - 0.28 12.0 3.0 0.47 11.2 3.0 1.3 1 0 0 1 1 1 0 DTHCT (NUC029) region DUF4633 PF15464.6 EAQ85000.1 - 0.21 11.7 1.4 0.25 11.5 1.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4633) CcmD PF04995.14 EAQ85001.1 - 0.055 13.6 0.4 0.055 13.6 0.4 2.1 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) TAF4 PF05236.14 EAQ85001.1 - 1.1 8.9 5.3 12 5.5 0.1 2.1 2 0 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family PhoD PF09423.10 EAQ85002.1 - 9.2e-108 360.4 5.8 1.1e-107 360.1 5.8 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase PhoD_N PF16655.5 EAQ85002.1 - 2.5e-31 108.1 0.1 5.6e-31 106.9 0.1 1.6 1 0 0 1 1 1 1 PhoD-like phosphatase, N-terminal domain Pur_ac_phosph_N PF16656.5 EAQ85002.1 - 4.9e-05 23.8 0.2 0.00012 22.6 0.2 1.7 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Metallophos PF00149.28 EAQ85002.1 - 0.069 13.6 3.7 0.14 12.7 3.6 1.6 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase Ank_2 PF12796.7 EAQ85003.1 - 6.1e-73 241.4 20.1 3.6e-16 59.5 0.1 10.2 5 3 3 10 10 10 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAQ85003.1 - 8.1e-66 217.6 21.5 3.8e-11 43.3 0.1 12.9 8 5 6 14 14 14 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAQ85003.1 - 1.6e-53 178.0 27.2 5.4e-09 36.1 0.3 11.8 10 2 2 12 12 12 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAQ85003.1 - 2.7e-51 165.6 30.8 3.7e-05 23.8 0.0 18.5 18 0 0 18 18 18 9 Ankyrin repeat Ank PF00023.30 EAQ85003.1 - 2.1e-48 160.8 44.5 4.4e-05 23.7 0.0 18.2 19 0 0 19 19 18 9 Ankyrin repeat Amino_oxidase PF01593.24 EAQ85003.1 - 3.8e-35 122.0 0.2 5.3e-21 75.4 0.0 2.8 1 1 1 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EAQ85003.1 - 4.3e-11 42.9 1.0 1.5e-10 41.1 0.2 2.4 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain AAA_22 PF13401.6 EAQ85003.1 - 2.5e-06 27.8 0.0 8.6e-06 26.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EAQ85003.1 - 3.5e-06 27.5 0.4 9.6e-05 22.8 0.0 3.3 3 0 0 3 3 3 1 AAA ATPase domain NACHT PF05729.12 EAQ85003.1 - 0.00011 22.2 0.0 0.00028 20.8 0.0 1.8 1 0 0 1 1 1 1 NACHT domain FAD_binding_2 PF00890.24 EAQ85003.1 - 0.00053 19.2 0.5 0.001 18.2 0.5 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 EAQ85003.1 - 0.00072 18.9 1.7 0.0016 17.8 1.7 1.5 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 EAQ85003.1 - 0.002 17.8 1.1 0.0055 16.3 0.5 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EAQ85003.1 - 0.0031 16.8 0.0 0.009 15.3 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EAQ85003.1 - 0.0032 16.7 0.8 0.006 15.8 0.8 1.4 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 EAQ85003.1 - 0.0046 15.7 0.5 0.064 11.9 0.3 2.2 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 EAQ85003.1 - 0.011 15.2 1.3 0.019 14.3 1.3 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase AAA PF00004.29 EAQ85003.1 - 0.018 15.5 0.0 0.048 14.1 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Pyr_redox PF00070.27 EAQ85003.1 - 0.036 14.6 1.0 0.14 12.8 1.0 2.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EAQ85003.1 - 0.092 12.0 0.1 0.19 10.9 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NB-ARC PF00931.22 EAQ85003.1 - 0.13 11.5 0.0 0.28 10.3 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain GIDA PF01134.22 EAQ85003.1 - 0.15 11.1 0.5 0.27 10.3 0.5 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A RNA_helicase PF00910.22 EAQ85003.1 - 0.15 12.4 0.0 0.51 10.7 0.0 1.9 2 0 0 2 2 1 0 RNA helicase APG6_N PF17675.1 EAQ85004.1 - 0.00083 19.9 4.2 0.0016 19.0 4.2 1.4 1 0 0 1 1 1 1 Apg6 coiled-coil region U79_P34 PF03064.16 EAQ85004.1 - 0.0047 16.3 2.9 0.0069 15.8 2.9 1.2 1 0 0 1 1 1 1 HSV U79 / HCMV P34 DUF874 PF05917.11 EAQ85004.1 - 0.046 12.7 4.7 0.064 12.3 4.7 1.1 1 0 0 1 1 1 0 Helicobacter pylori protein of unknown function (DUF874) DUF612 PF04747.12 EAQ85004.1 - 0.049 12.7 7.5 0.063 12.4 7.5 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF612 Atg14 PF10186.9 EAQ85004.1 - 0.41 9.7 4.6 0.6 9.1 4.6 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 CAMSAP_CC1 PF17095.5 EAQ85004.1 - 3.2 7.7 22.7 15 5.5 5.8 3.4 1 1 2 3 3 3 0 Spectrin-binding region of Ca2+-Calmodulin PGBA_C PF15437.6 EAQ85004.1 - 7.4 7.0 19.3 41 4.6 19.3 2.0 1 1 0 1 1 1 0 Plasminogen-binding protein pgbA C-terminal BNR_2 PF13088.6 EAQ85006.1 - 3.9e-11 42.8 0.3 1.2e-10 41.2 0.3 1.8 1 1 0 1 1 1 1 BNR repeat-like domain BNR_3 PF13859.6 EAQ85006.1 - 7.6e-09 35.3 0.0 1e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 BNR repeat-like domain BNR PF02012.20 EAQ85006.1 - 1.6 9.0 4.1 2.4 8.5 1.2 3.1 2 0 0 2 2 2 0 BNR/Asp-box repeat UvrD_C PF13361.6 EAQ85007.1 - 6.8e-62 209.9 0.0 2e-61 208.3 0.0 1.8 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.21 EAQ85007.1 - 2.6e-61 207.9 0.2 9.5e-60 202.7 0.2 2.4 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 EAQ85007.1 - 1.8e-29 103.0 0.0 3.4e-29 102.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 EAQ85007.1 - 4.1e-14 52.1 0.0 1.1e-13 50.8 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 EAQ85007.1 - 8.5e-09 35.4 0.2 6.4e-05 22.7 0.2 2.3 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 EAQ85007.1 - 2.5e-05 24.1 0.0 0.27 10.9 0.0 3.3 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_12 PF13087.6 EAQ85007.1 - 9.7e-05 22.1 0.0 0.0057 16.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain Membralin PF09746.9 EAQ85007.1 - 0.13 11.3 0.1 0.22 10.5 0.1 1.2 1 0 0 1 1 1 0 Tumour-associated protein 23ISL PF16620.5 EAQ85007.1 - 2.3 8.4 7.0 0.37 11.0 2.6 1.9 2 0 0 2 2 2 0 Unstructured linker between I-set domains 2 and 3 on MYLCK Mucin PF01456.17 EAQ85008.1 - 0.014 15.4 6.1 0.017 15.1 6.1 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein CoatB PF10389.9 EAQ85008.1 - 0.049 13.5 1.6 0.11 12.4 1.6 1.5 1 0 0 1 1 1 0 Bacteriophage coat protein B Pkinase PF00069.25 EAQ85009.1 - 4.2e-21 75.5 0.0 4.9e-21 75.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ85009.1 - 1.5e-10 40.8 0.0 1.9e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EAQ85009.1 - 5.8e-05 22.2 0.0 7.3e-05 21.9 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EAQ85009.1 - 0.0033 17.4 0.0 0.0045 16.9 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EAQ85009.1 - 0.018 13.9 0.0 0.023 13.5 0.0 1.0 1 0 0 1 1 1 0 Fungal protein kinase Choline_kinase PF01633.20 EAQ85009.1 - 0.049 13.2 0.0 0.065 12.8 0.0 1.1 1 0 0 1 1 1 0 Choline/ethanolamine kinase EcKinase PF02958.20 EAQ85009.1 - 0.19 11.0 0.0 0.26 10.5 0.0 1.1 1 0 0 1 1 1 0 Ecdysteroid kinase Kdo PF06293.14 EAQ85009.1 - 0.22 10.8 0.0 0.28 10.5 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1604 PF07713.13 EAQ85010.1 - 1.4e-34 117.8 1.6 1.4e-34 117.8 1.6 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF1604) G-patch PF01585.23 EAQ85010.1 - 1.5e-07 31.1 1.9 1.5e-06 28.0 1.6 2.7 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 EAQ85010.1 - 0.0013 18.7 1.6 0.003 17.6 0.2 2.4 2 0 0 2 2 2 1 G-patch domain DHDPS PF00701.22 EAQ85012.1 - 1.4e-13 50.2 0.0 2.5e-13 49.4 0.0 1.4 1 1 1 2 2 2 1 Dihydrodipicolinate synthetase family TPR_10 PF13374.6 EAQ85012.1 - 0.094 12.6 0.7 3.9 7.5 0.4 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF1771 PF08590.10 EAQ85012.1 - 1 9.7 4.3 3.7 8.0 0.0 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF1771) WD40 PF00400.32 EAQ85014.1 - 4.1e-22 78.0 23.8 1.3e-05 25.9 0.2 6.9 6 2 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAQ85014.1 - 5.8e-11 42.5 7.1 2.4e-05 24.5 0.3 4.2 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain TFIIIC_delta PF12657.7 EAQ85014.1 - 4.7e-05 23.4 6.5 0.012 15.5 0.7 2.8 1 1 1 2 2 2 2 Transcription factor IIIC subunit delta N-term Acetyltransf_11 PF13720.6 EAQ85016.1 - 0.071 13.6 0.0 0.19 12.2 0.0 1.7 1 1 0 1 1 1 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 DOPA_dioxygen PF08883.11 EAQ85018.1 - 4.9e-43 145.7 0.0 6.3e-43 145.3 0.0 1.1 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family Podoplanin PF05808.11 EAQ85019.1 - 0.01 16.0 0.5 0.022 14.9 0.5 1.6 1 0 0 1 1 1 1 Podoplanin TPR_MLP1_2 PF07926.12 EAQ85020.1 - 9.6e-38 129.2 32.4 9.6e-38 129.2 32.4 19.0 11 6 5 17 17 17 5 TPR/MLP1/MLP2-like protein CALCOCO1 PF07888.11 EAQ85020.1 - 0.0014 17.6 40.0 0.0014 17.6 40.0 8.9 4 3 4 8 8 8 1 Calcium binding and coiled-coil domain (CALCOCO1) like Scm3 PF10384.9 EAQ85020.1 - 0.0056 16.4 1.9 0.034 13.9 0.0 3.4 2 0 0 2 2 2 1 Centromere protein Scm3 HIP1_clath_bdg PF16515.5 EAQ85020.1 - 0.01 16.4 5.3 0.01 16.4 5.3 20.1 7 4 13 22 22 22 0 Clathrin-binding domain of Huntingtin-interacting protein 1 JIP_LZII PF16471.5 EAQ85020.1 - 0.012 15.8 1.0 0.012 15.8 1.0 21.4 17 6 8 25 25 25 0 JNK-interacting protein leucine zipper II Qua1 PF16274.5 EAQ85020.1 - 0.025 14.4 0.2 0.28 11.0 0.2 3.0 1 0 0 1 1 1 0 Qua1 domain DUF3693 PF12472.8 EAQ85020.1 - 0.058 13.1 0.6 0.35 10.5 0.6 2.4 1 0 0 1 1 1 0 Phage related protein Cep57_CLD_2 PF14197.6 EAQ85020.1 - 0.067 13.3 0.1 0.067 13.3 0.1 20.4 14 6 6 22 22 22 0 Centrosome localisation domain of PPC89 MtrG PF04210.13 EAQ85020.1 - 0.23 11.3 0.2 5.3 7.0 0.0 3.7 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G YopE_N PF09020.10 EAQ85021.1 - 0.045 14.0 0.1 0.045 14.0 0.1 2.1 2 0 0 2 2 2 0 YopE, N terminal Gemini_C4 PF01492.17 EAQ85021.1 - 0.072 13.0 0.2 0.25 11.3 0.1 2.1 2 0 0 2 2 2 0 Geminivirus C4 protein bZIP_1 PF00170.21 EAQ85021.1 - 0.67 10.1 6.5 2.5 8.3 6.5 1.8 1 1 0 1 1 1 0 bZIP transcription factor Tubulin PF00091.25 EAQ85025.1 - 6.8e-46 157.0 0.0 1.9e-45 155.5 0.0 1.7 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EAQ85025.1 - 3.3e-43 146.8 0.1 5e-43 146.3 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_2 PF13809.6 EAQ85025.1 - 0.001 18.4 0.0 0.018 14.2 0.0 2.1 2 0 0 2 2 2 1 Tubulin like Tubulin_3 PF14881.6 EAQ85025.1 - 0.0016 18.1 0.0 0.0027 17.4 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain ABC_tran PF00005.27 EAQ85026.1 - 7e-49 165.9 0.7 9.3e-23 81.3 0.0 3.3 3 0 0 3 3 3 2 ABC transporter ABC_tran_Xtn PF12848.7 EAQ85026.1 - 1.3e-19 70.0 7.4 1.3e-19 70.0 7.4 4.2 4 1 1 5 5 4 1 ABC transporter AAA_21 PF13304.6 EAQ85026.1 - 1.9e-17 64.1 1.5 0.00038 20.4 0.0 4.4 3 1 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EAQ85026.1 - 1.4e-10 41.0 6.3 0.00092 18.7 0.0 4.6 5 0 0 5 5 5 4 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EAQ85026.1 - 5.5e-06 26.0 0.1 0.16 11.7 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 EAQ85026.1 - 1.1e-05 25.9 0.3 0.046 14.1 0.1 2.7 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 EAQ85026.1 - 1.7e-05 24.8 1.7 0.09 12.9 0.2 3.0 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.6 EAQ85026.1 - 2e-05 25.2 21.8 0.005 17.4 0.0 5.0 5 0 0 5 5 5 2 AAA domain RsgA_GTPase PF03193.16 EAQ85026.1 - 2.8e-05 24.1 1.1 0.35 10.7 0.0 3.0 2 1 1 3 3 3 2 RsgA GTPase AAA_18 PF13238.6 EAQ85026.1 - 3.6e-05 24.3 0.1 0.67 10.5 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.6 EAQ85026.1 - 6.4e-05 23.3 0.0 0.21 11.9 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 EAQ85026.1 - 7.6e-05 22.5 1.2 0.0042 16.8 0.0 3.1 3 1 0 3 3 3 1 AAA domain AAA_33 PF13671.6 EAQ85026.1 - 9.8e-05 22.5 0.1 0.65 10.2 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 EAQ85026.1 - 0.00011 22.5 1.4 0.078 13.2 0.0 3.1 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 EAQ85026.1 - 0.00035 21.0 0.1 0.43 11.0 0.1 3.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 EAQ85026.1 - 0.00068 19.4 2.7 1 9.1 0.1 3.3 3 0 0 3 3 3 2 AAA domain AAA_15 PF13175.6 EAQ85026.1 - 0.0016 18.2 19.2 0.078 12.7 0.0 5.3 4 1 2 6 6 6 2 AAA ATPase domain NACHT PF05729.12 EAQ85026.1 - 0.0023 17.8 0.2 2.4 8.1 0.0 2.8 2 0 0 2 2 2 1 NACHT domain RNA_helicase PF00910.22 EAQ85026.1 - 0.005 17.2 0.0 2.5 8.5 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_14 PF13173.6 EAQ85026.1 - 0.0054 16.8 0.0 1.9 8.5 0.0 3.0 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 EAQ85026.1 - 0.0067 16.4 1.3 7.1 6.5 0.0 3.5 3 1 1 4 4 4 0 Rad17 P-loop domain Roc PF08477.13 EAQ85026.1 - 0.0074 16.5 0.1 5.9 7.1 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NTPase_1 PF03266.15 EAQ85026.1 - 0.0089 16.0 0.0 0.78 9.6 0.0 2.7 2 0 0 2 2 2 1 NTPase AAA_7 PF12775.7 EAQ85026.1 - 0.011 15.3 0.0 3.5 7.1 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region MobB PF03205.14 EAQ85026.1 - 0.016 15.1 0.0 0.39 10.6 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NB-ARC PF00931.22 EAQ85026.1 - 0.022 14.0 0.0 3.6 6.7 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain Dynamin_N PF00350.23 EAQ85026.1 - 0.033 14.3 8.5 1.8 8.6 0.1 4.4 4 1 0 4 4 4 0 Dynamin family ATP-synt_ab PF00006.25 EAQ85026.1 - 0.035 13.8 0.1 1.7 8.3 0.0 2.6 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_5 PF07728.14 EAQ85026.1 - 0.035 14.1 0.2 7.5 6.6 0.0 2.8 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) Halo_GVPC PF05465.13 EAQ85026.1 - 0.036 14.3 0.6 0.17 12.2 0.2 2.3 2 0 0 2 2 2 0 Halobacterial gas vesicle protein C (GVPC) repeat TsaE PF02367.17 EAQ85026.1 - 0.041 13.9 0.0 6.4 6.8 0.0 2.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE cobW PF02492.19 EAQ85026.1 - 0.067 12.8 2.7 1.2 8.7 0.4 2.7 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 EAQ85026.1 - 0.11 11.4 5.9 3.1 6.7 0.0 3.1 4 0 0 4 4 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_27 PF13514.6 EAQ85026.1 - 1.4 8.4 11.5 4.9 6.7 0.0 4.2 6 0 0 6 6 3 0 AAA domain bZIP_2 PF07716.15 EAQ85028.1 - 5.6e-06 26.3 5.2 1e-05 25.5 5.2 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 EAQ85028.1 - 1.4e-05 25.1 4.1 2.1e-05 24.5 4.1 1.2 1 0 0 1 1 1 1 bZIP transcription factor A_deaminase PF00962.22 EAQ85029.1 - 5.2e-19 68.7 0.4 1.5e-15 57.4 0.0 3.0 3 0 0 3 3 3 2 Adenosine/AMP deaminase A_deaminase_N PF08451.11 EAQ85029.1 - 0.013 15.8 0.4 0.049 13.9 0.4 2.0 1 1 0 1 1 1 0 Adenosine/AMP deaminase N-terminal SRP40_C PF05022.12 EAQ85030.1 - 8.2e-24 84.3 1.1 8.2e-24 84.3 1.1 2.6 2 0 0 2 2 2 1 SRP40, C-terminal domain FA_desaturase PF00487.24 EAQ85031.1 - 0.0012 18.8 0.8 0.85 9.4 0.0 2.1 2 0 0 2 2 2 2 Fatty acid desaturase DUF1673 PF07895.11 EAQ85031.1 - 0.0034 17.1 0.3 0.11 12.2 0.3 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1673) SUR7 PF06687.12 EAQ85031.1 - 0.021 14.5 1.0 0.032 13.9 1.0 1.3 1 1 0 1 1 1 0 SUR7/PalI family DUF1676 PF07898.13 EAQ85031.1 - 0.13 12.2 0.2 4.2 7.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1676) DUF2207 PF09972.9 EAQ85031.1 - 0.89 8.2 2.7 5 5.8 0.1 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF4191 PF13829.6 EAQ85031.1 - 1.2 8.5 6.1 1.8 7.9 0.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) Complex1_51K PF01512.17 EAQ85033.1 - 3.5e-49 166.6 0.0 5.9e-49 165.8 0.0 1.4 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 EAQ85033.1 - 1.5e-28 98.7 1.3 1.9e-28 98.3 0.2 1.8 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 EAQ85033.1 - 3.7e-09 36.3 0.1 1.8e-08 34.1 0.0 2.2 2 0 0 2 2 2 1 SLBB domain Flavoprotein PF02441.19 EAQ85034.1 - 4.4e-20 72.0 0.0 7.1e-20 71.4 0.0 1.3 1 0 0 1 1 1 1 Flavoprotein Ank_4 PF13637.6 EAQ85034.1 - 0.027 15.1 0.0 47 4.7 0.0 4.1 3 1 0 3 3 3 0 Ankyrin repeats (many copies) DUF3431 PF11913.8 EAQ85035.1 - 1e-89 300.0 0.0 1.2e-89 299.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) zf-RVT PF13966.6 EAQ85036.1 - 0.1 13.3 0.0 0.46 11.2 0.0 1.8 2 0 0 2 2 2 0 zinc-binding in reverse transcriptase Abhydrolase_4 PF08386.10 EAQ85038.1 - 5.6e-23 81.0 0.0 2e-22 79.3 0.0 1.9 2 0 0 2 2 2 1 TAP-like protein Abhydrolase_1 PF00561.20 EAQ85038.1 - 1.2e-17 64.4 0.0 3.9e-14 52.9 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Ank_2 PF12796.7 EAQ85039.1 - 2e-84 278.2 0.0 2e-11 44.3 0.5 9.6 1 1 10 11 11 11 11 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAQ85039.1 - 1.1e-57 191.7 10.7 2.7e-05 24.6 0.0 13.7 6 3 7 14 14 14 13 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAQ85039.1 - 4.7e-56 186.1 19.1 5.6e-08 32.9 0.1 15.8 7 5 8 16 16 16 13 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAQ85039.1 - 3.3e-46 149.9 8.4 0.0042 17.5 0.0 18.0 18 0 0 18 18 18 10 Ankyrin repeat Ank PF00023.30 EAQ85039.1 - 1.8e-45 151.4 17.0 0.0023 18.3 0.0 16.4 18 0 0 18 18 18 11 Ankyrin repeat DUF1884 PF08967.10 EAQ85039.1 - 0.17 12.2 0.0 0.44 10.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1884) Hira PF07569.11 EAQ85041.1 - 5.1e-82 274.9 0.0 1.2e-81 273.7 0.0 1.7 1 0 0 1 1 1 1 TUP1-like enhancer of split WD40 PF00400.32 EAQ85041.1 - 3.6e-27 94.0 25.8 1.3e-05 25.9 0.1 8.6 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAQ85041.1 - 3.8e-14 52.7 0.0 0.082 13.2 0.0 6.4 4 1 3 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain HIRA_B PF09453.10 EAQ85041.1 - 1.1e-10 41.1 0.5 2.2e-10 40.2 0.5 1.6 1 0 0 1 1 1 1 HIRA B motif PD40 PF07676.12 EAQ85041.1 - 4e-05 23.4 0.6 15 5.6 0.0 4.8 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 EAQ85041.1 - 5.2e-05 22.4 0.5 0.37 9.7 0.0 4.2 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Cohesin PF00963.18 EAQ85042.1 - 0.064 13.5 5.0 0.082 13.2 5.0 1.2 1 0 0 1 1 1 0 Cohesin domain Peptidase_M24 PF00557.24 EAQ85043.1 - 3.4e-41 141.2 0.1 4.6e-41 140.8 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 YL1 PF05764.13 EAQ85043.1 - 0.07 13.2 6.3 0.1 12.7 6.3 1.1 1 0 0 1 1 1 0 YL1 nuclear protein DUF1168 PF06658.12 EAQ85043.1 - 0.13 12.1 7.1 0.28 11.0 7.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) CDC45 PF02724.14 EAQ85043.1 - 1.9 6.7 3.5 2.8 6.1 3.5 1.2 1 0 0 1 1 1 0 CDC45-like protein Coilin_N PF15862.5 EAQ85043.1 - 2.2 8.1 5.9 5.1 6.9 5.9 1.5 1 0 0 1 1 1 0 Coilin N-terminus SBP56 PF05694.11 EAQ85044.1 - 0.0025 16.7 0.0 0.021 13.6 0.0 2.1 2 0 0 2 2 2 1 56kDa selenium binding protein (SBP56) Lactonase PF10282.9 EAQ85044.1 - 0.0037 16.6 0.0 0.025 13.8 0.0 2.0 2 0 0 2 2 2 1 Lactonase, 7-bladed beta-propeller SGL PF08450.12 EAQ85044.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 EAQ85044.1 - 0.16 12.0 0.0 51 4.2 0.0 3.1 3 0 0 3 3 3 0 NHL repeat FtsJ PF01728.19 EAQ85045.1 - 5.2e-63 212.3 0.0 6.8e-63 212.0 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase DEAD PF00270.29 EAQ85046.1 - 2.6e-42 144.6 0.0 4.4e-42 143.8 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EAQ85046.1 - 7.6e-14 52.0 0.0 2.2e-13 50.5 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Coilin_N PF15862.5 EAQ85046.1 - 3.2e-05 23.7 1.3 6.7e-05 22.7 0.0 2.1 1 1 1 2 2 2 1 Coilin N-terminus ResIII PF04851.15 EAQ85046.1 - 0.00018 21.6 0.4 0.00053 20.0 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit RR_TM4-6 PF06459.12 EAQ85046.1 - 0.15 11.9 12.2 0.33 10.7 12.2 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 AAA_11 PF13086.6 EAQ85046.1 - 0.21 11.4 7.1 4.4 7.0 0.0 2.9 3 0 0 3 3 3 0 AAA domain TIMELESS_C PF05029.13 EAQ85046.1 - 0.48 9.5 17.8 1.2 8.2 17.8 1.6 1 0 0 1 1 1 0 Timeless protein C terminal region Tim54 PF11711.8 EAQ85046.1 - 1.7 7.4 8.9 2.9 6.6 8.9 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Sortilin-Vps10 PF15902.5 EAQ85047.1 - 1.7e-20 73.2 0.7 5.4e-06 25.5 0.0 6.4 4 2 3 7 7 7 6 Sortilin, neurotensin receptor 3, CBM_1 PF00734.18 EAQ85047.1 - 3.4e-12 46.1 13.1 1e-11 44.6 13.1 1.9 1 0 0 1 1 1 1 Fungal cellulose binding domain BNR PF02012.20 EAQ85047.1 - 1.7e-09 36.2 31.7 0.46 10.7 0.1 10.2 9 0 0 9 9 9 5 BNR/Asp-box repeat BNR_6 PF15899.5 EAQ85047.1 - 4.4e-07 29.4 4.0 0.88 9.8 0.0 7.5 7 0 0 7 7 7 2 BNR-Asp box repeat His_Phos_2 PF00328.22 EAQ85048.1 - 6.6e-24 85.0 0.0 9.2e-24 84.5 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Glyco_hydro_2_C PF02836.17 EAQ85049.1 - 3e-103 345.1 0.0 4.5e-103 344.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Ank_2 PF12796.7 EAQ85049.1 - 4.3e-98 322.0 45.4 1e-16 61.2 0.5 7.0 1 1 9 10 10 10 10 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAQ85049.1 - 2.1e-84 276.9 32.7 9.6e-11 42.0 0.1 13.3 2 1 11 13 13 13 12 Ankyrin repeats (many copies) Bgal_small_N PF02929.17 EAQ85049.1 - 3.3e-61 207.0 0.1 5.8e-61 206.2 0.1 1.4 1 0 0 1 1 1 1 Beta galactosidase small chain Ank PF00023.30 EAQ85049.1 - 2.3e-59 195.4 23.0 0.00012 22.3 0.0 13.3 13 0 0 13 13 13 12 Ankyrin repeat Ank_3 PF13606.6 EAQ85049.1 - 2.8e-53 171.6 12.3 0.0056 17.1 0.0 14.1 14 0 0 14 14 13 12 Ankyrin repeat Ank_5 PF13857.6 EAQ85049.1 - 8.8e-49 162.9 9.2 9.1e-07 29.0 0.1 7.9 5 1 3 8 8 8 8 Ankyrin repeats (many copies) Glyco_hydro_2_N PF02837.18 EAQ85049.1 - 1.3e-37 129.3 0.0 2.9e-37 128.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain PNP_UDP_1 PF01048.20 EAQ85049.1 - 6.6e-14 51.7 1.8 2.6e-13 49.8 0.1 2.5 2 1 0 2 2 2 1 Phosphorylase superfamily Glyco_hydro_2 PF00703.21 EAQ85049.1 - 2.2e-07 31.5 0.0 4.4e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 DUF4981 PF16353.5 EAQ85049.1 - 1.8e-06 28.3 0.1 2.1e-05 24.9 0.1 2.5 1 1 0 1 1 1 1 Domain of unknown function(DUF4981) NACHT PF05729.12 EAQ85049.1 - 0.0048 16.8 0.0 0.013 15.4 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 EAQ85049.1 - 0.056 13.7 0.0 0.22 11.8 0.0 2.0 1 0 0 1 1 1 0 AAA domain Nse4-Nse3_bdg PF15412.6 EAQ85049.1 - 0.3 11.2 13.6 11 6.2 0.1 6.0 6 0 0 6 6 6 0 Binding domain of Nse4/EID3 to Nse3-MAGE DEAD PF00270.29 EAQ85052.1 - 4.4e-22 78.7 0.0 1.6e-21 76.8 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EAQ85052.1 - 4.1e-17 62.5 0.0 3.1e-14 53.3 0.0 2.4 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 EAQ85052.1 - 0.00078 19.5 0.0 0.0014 18.7 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit RecQ_Zn_bind PF16124.5 EAQ85052.1 - 0.0011 19.6 0.1 0.004 17.9 0.1 1.9 2 0 0 2 2 2 1 RecQ zinc-binding TrbI_Ftype PF09677.10 EAQ85052.1 - 0.1 12.9 0.0 0.25 11.7 0.0 1.6 1 0 0 1 1 1 0 Type-F conjugative transfer system protein (TrbI_Ftype) DUF99 PF01949.16 EAQ85052.1 - 0.14 11.5 0.0 0.39 10.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function DUF99 Rrf2 PF02082.20 EAQ85052.1 - 0.18 12.2 0.0 25 5.3 0.0 2.5 2 0 0 2 2 2 0 Transcriptional regulator Mannosyl_trans2 PF04188.13 EAQ85054.1 - 1.1e-52 179.8 0.2 7.5e-52 177.1 0.2 1.9 1 1 0 1 1 1 1 Mannosyltransferase (PIG-V) YTH PF04146.15 EAQ85055.1 - 0.00026 21.0 0.1 0.0081 16.1 0.0 3.4 2 2 0 3 3 3 2 YT521-B-like domain Glyco_hydro_61 PF03443.14 EAQ85056.1 - 8.9e-57 192.3 0.0 1.1e-56 192.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CSD PF00313.22 EAQ85056.1 - 0.16 11.8 0.0 0.31 10.9 0.0 1.3 1 0 0 1 1 1 0 'Cold-shock' DNA-binding domain TALPID3 PF15324.6 EAQ85056.1 - 8.4 3.9 9.6 10 3.6 9.6 1.1 1 0 0 1 1 1 0 Hedgehog signalling target CFEM PF05730.11 EAQ85057.1 - 2.1e-13 50.1 9.6 4.8e-13 49.0 9.6 1.6 1 0 0 1 1 1 1 CFEM domain p450 PF00067.22 EAQ85058.1 - 1.2e-54 185.8 0.0 1.6e-54 185.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Transgly_assoc PF04226.13 EAQ85058.1 - 1.1 9.6 4.0 2.8 8.3 4.0 1.7 1 0 0 1 1 1 0 Transglycosylase associated protein MscS_TM PF12794.7 EAQ85059.1 - 0.052 12.4 0.2 0.052 12.4 0.2 2.4 2 0 0 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 PET117 PF15786.5 EAQ85059.1 - 0.25 11.6 0.0 0.51 10.6 0.0 1.5 1 0 0 1 1 1 0 PET assembly of cytochrome c oxidase, mitochondrial Velvet PF11754.8 EAQ85063.1 - 2e-38 132.8 11.2 6.9e-31 108.1 0.3 3.0 2 1 1 3 3 3 2 Velvet factor GH101_N PF17995.1 EAQ85064.1 - 0.13 11.9 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 Endo-alpha-N-acetylgalactosaminidase N-terminal DRMBL PF07522.14 EAQ85065.1 - 0.00044 20.4 0.0 0.00096 19.3 0.0 1.5 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase RMMBL PF07521.12 EAQ85065.1 - 0.088 12.8 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Zn-dependent metallo-hydrolase RNA specificity domain p450 PF00067.22 EAQ85066.1 - 2.4e-30 105.7 0.0 3.1e-30 105.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_43 PF04616.14 EAQ85067.1 - 2.9e-60 204.0 6.3 3.3e-60 203.9 6.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 PD40 PF07676.12 EAQ85067.1 - 2.6 8.1 5.9 0.39 10.7 0.3 2.5 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat DUF572 PF04502.13 EAQ85068.1 - 3.4e-64 217.6 0.0 4e-64 217.3 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) UQ_con PF00179.26 EAQ85069.1 - 5.9e-34 116.7 0.0 7.1e-34 116.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Pantoate_transf PF02548.15 EAQ85070.1 - 2.7e-107 358.0 0.2 3.1e-107 357.8 0.2 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 EAQ85070.1 - 2.4e-09 37.0 0.4 7.4e-09 35.4 0.1 1.8 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase Asp_Glu_race PF01177.22 EAQ85070.1 - 0.077 12.8 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Asp/Glu/Hydantoin racemase APG12 PF04110.13 EAQ85071.1 - 1.4e-26 92.7 0.0 1.7e-26 92.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.16 EAQ85071.1 - 0.00021 21.5 0.0 0.00023 21.3 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like HLH PF00010.26 EAQ85072.1 - 2.2e-14 53.2 0.4 7.6e-14 51.4 0.1 2.1 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Sigma70_ner PF04546.13 EAQ85072.1 - 0.037 13.9 0.4 0.059 13.3 0.4 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region SLX9 PF15341.6 EAQ85072.1 - 0.11 12.9 2.8 0.13 12.7 0.9 2.1 2 0 0 2 2 2 0 Ribosome biogenesis protein SLX9 DASH_Hsk3 PF08227.11 EAQ85072.1 - 0.34 11.3 4.8 0.66 10.4 4.8 1.5 1 0 0 1 1 1 0 DASH complex subunit Hsk3 like AMP_N PF05195.16 EAQ85073.1 - 1.2e-33 115.5 0.0 1.9e-33 114.8 0.0 1.3 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Peptidase_M24 PF00557.24 EAQ85073.1 - 3.5e-22 79.1 0.0 5.2e-22 78.6 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Dfp1_Him1_M PF08630.10 EAQ85074.1 - 3.5e-39 133.9 0.0 6.7e-39 133.0 0.0 1.5 1 0 0 1 1 1 1 Dfp1/Him1, central region zf-DBF PF07535.12 EAQ85074.1 - 3.4e-21 75.1 0.6 6e-21 74.3 0.6 1.4 1 0 0 1 1 1 1 DBF zinc finger GFO_IDH_MocA PF01408.22 EAQ85074.1 - 3.3e-10 40.8 0.0 7.1e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold PTCB-BRCT PF12738.7 EAQ85074.1 - 0.018 14.9 0.0 0.039 13.9 0.0 1.5 1 0 0 1 1 1 0 twin BRCT domain BRCT PF00533.26 EAQ85074.1 - 0.19 12.1 0.0 0.4 11.1 0.0 1.5 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain DHDPS PF00701.22 EAQ85077.1 - 1.7e-37 128.7 0.0 2.7e-37 128.1 0.0 1.2 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Ecl1 PF12855.7 EAQ85077.1 - 0.14 13.3 2.9 0.22 12.7 2.9 1.3 1 0 0 1 1 1 0 ECL1/2/3 zinc binding proteins Tyrosinase PF00264.20 EAQ85078.1 - 1.8e-17 64.4 0.0 8.3e-17 62.2 0.0 1.9 1 1 0 1 1 1 1 Common central domain of tyrosinase Tyosinase_C PF18132.1 EAQ85078.1 - 3.2e-06 27.8 0.0 6e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Tyosinase C-terminal domain Glyco_hydro_16 PF00722.21 EAQ85079.1 - 1.4e-32 112.5 0.3 1.4e-32 112.5 0.3 2.0 2 1 0 2 2 2 1 Glycosyl hydrolases family 16 Phage_holin_2_4 PF16082.5 EAQ85079.1 - 0.033 13.9 1.3 0.033 13.9 1.3 1.9 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like SOG2 PF10428.9 EAQ85079.1 - 1.8 7.7 11.6 2.4 7.3 11.6 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Mucin PF01456.17 EAQ85079.1 - 4.8 7.2 27.0 9.5 6.2 27.0 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein Miga PF10265.9 EAQ85079.1 - 7.8 5.3 6.0 10 4.9 6.0 1.1 1 0 0 1 1 1 0 Mitoguardin SKG6 PF08693.10 EAQ85080.1 - 7.9e-14 50.8 7.4 1.4e-13 50.0 7.4 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4448 PF14610.6 EAQ85080.1 - 0.0022 17.8 0.3 0.0053 16.5 0.3 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF4448) Podoplanin PF05808.11 EAQ85080.1 - 0.019 15.1 4.7 0.042 13.9 4.7 1.5 1 0 0 1 1 1 0 Podoplanin TMEM154 PF15102.6 EAQ85080.1 - 0.022 14.7 0.0 0.047 13.6 0.0 1.4 1 0 0 1 1 1 0 TMEM154 protein family DUF2207 PF09972.9 EAQ85080.1 - 0.042 12.6 0.0 0.063 12.0 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4381 PF14316.6 EAQ85080.1 - 0.048 13.9 0.2 0.31 11.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) ChpA-C PF03777.13 EAQ85080.1 - 0.88 9.5 6.2 2.9 7.8 6.2 1.9 1 0 0 1 1 1 0 ChpA-C RXT2_N PF08595.11 EAQ85081.1 - 1.1e-13 51.5 5.0 3.5e-06 27.1 0.1 3.0 3 0 0 3 3 3 2 RXT2-like, N-terminal MFS_1 PF07690.16 EAQ85082.1 - 9.3e-36 123.5 65.7 3.6e-35 121.5 62.5 3.3 2 1 0 2 2 2 1 Major Facilitator Superfamily Fungal_trans PF04082.18 EAQ85083.1 - 6.2e-20 71.3 0.0 1.9e-19 69.8 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EAQ85083.1 - 0.037 14.2 2.1 0.072 13.2 2.1 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain SfsA_N PF17746.1 EAQ85083.1 - 0.17 12.0 0.0 0.42 10.8 0.0 1.6 1 0 0 1 1 1 0 SfsA N-terminal OB domain Acetyltransf_1 PF00583.25 EAQ85084.1 - 7.9e-08 32.5 0.0 1.6e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EAQ85084.1 - 1.7e-07 31.2 0.0 3.7e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EAQ85084.1 - 1.1e-06 29.0 0.0 2.1e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Fungal_trans_2 PF11951.8 EAQ85084.1 - 0.00024 20.0 2.5 0.00037 19.4 2.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain FR47 PF08445.10 EAQ85084.1 - 0.0017 18.2 0.0 0.0036 17.2 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 EAQ85084.1 - 0.01 15.9 0.0 0.023 14.8 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EAQ85084.1 - 0.037 14.1 0.0 0.091 12.9 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase adh_short PF00106.25 EAQ85086.1 - 9.5e-05 21.9 0.0 0.87 9.0 0.0 3.4 2 1 0 2 2 2 2 short chain dehydrogenase MFS_1 PF07690.16 EAQ85087.1 - 4.1e-22 78.6 36.8 4.1e-22 78.6 36.8 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily UCR_hinge PF02320.16 EAQ85088.1 - 1.3e-27 95.8 8.6 1.3e-27 95.8 8.6 1.9 2 1 0 2 2 1 1 Ubiquinol-cytochrome C reductase hinge protein Mpp10 PF04006.12 EAQ85088.1 - 0.022 13.3 16.4 0.026 13.0 16.4 1.0 1 0 0 1 1 1 0 Mpp10 protein RR_TM4-6 PF06459.12 EAQ85088.1 - 0.33 10.7 18.8 0.38 10.5 18.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SAPS PF04499.15 EAQ85088.1 - 0.38 9.5 7.6 0.41 9.4 7.6 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein LAP1C PF05609.12 EAQ85088.1 - 0.45 9.5 13.6 0.5 9.4 13.6 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF913 PF06025.12 EAQ85088.1 - 0.6 9.0 7.0 0.65 8.9 7.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Lin-8 PF03353.15 EAQ85088.1 - 1.5 8.3 12.7 1.7 8.1 12.7 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Nop14 PF04147.12 EAQ85088.1 - 1.6 6.9 19.3 1.7 6.8 19.3 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 EAQ85088.1 - 2 6.6 12.2 2 6.6 12.2 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4045 PF13254.6 EAQ85088.1 - 2.2 7.8 15.1 2.6 7.6 15.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) BUD22 PF09073.10 EAQ85088.1 - 2.7 7.2 19.9 3.2 7.0 19.9 1.0 1 0 0 1 1 1 0 BUD22 Asp-B-Hydro_N PF05279.11 EAQ85088.1 - 3 7.9 25.4 3.6 7.6 25.4 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Tim54 PF11711.8 EAQ85088.1 - 3.3 6.4 16.3 3.9 6.2 16.3 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Presenilin PF01080.17 EAQ85088.1 - 3.7 6.2 12.8 4.1 6.1 12.8 1.0 1 0 0 1 1 1 0 Presenilin Pox_Ag35 PF03286.14 EAQ85088.1 - 4.7 6.9 17.4 6.7 6.4 17.4 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF4471 PF14740.6 EAQ85088.1 - 4.9 6.3 7.4 8 5.6 7.4 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4471) Mitofilin PF09731.9 EAQ85088.1 - 5.4 5.7 19.9 6.2 5.5 19.9 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Raftlin PF15250.6 EAQ85088.1 - 5.5 5.6 10.8 6.1 5.5 10.8 1.1 1 0 0 1 1 1 0 Raftlin DUF4746 PF15928.5 EAQ85088.1 - 6.1 6.2 25.5 8.2 5.8 25.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) SLC12 PF03522.15 EAQ85088.1 - 6.4 5.7 5.9 6.9 5.6 5.9 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Hid1 PF12722.7 EAQ85088.1 - 6.6 4.7 9.9 7.3 4.6 9.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein eIF3_subunit PF08597.10 EAQ85088.1 - 7.1 6.5 25.9 7.6 6.4 25.9 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Neur_chan_memb PF02932.16 EAQ85088.1 - 8.5 6.4 6.7 9.6 6.2 6.7 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Nop53 PF07767.11 EAQ85088.1 - 8.6 5.6 24.9 9.4 5.5 24.9 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) WTX PF09422.10 EAQ85088.1 - 9.6 5.1 18.3 11 4.9 18.3 1.1 1 0 0 1 1 1 0 WTX protein NPR3 PF03666.13 EAQ85088.1 - 10 4.8 9.1 10 4.7 9.1 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Pex14_N PF04695.13 EAQ85089.1 - 2.9 8.5 15.0 4.5 7.9 15.0 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CCDC53 PF10152.9 EAQ85089.1 - 3.2 8.2 7.5 4.9 7.6 7.5 1.3 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex TFIIA PF03153.13 EAQ85089.1 - 7.1 6.5 15.6 8.4 6.3 15.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Drf_GBD PF06371.13 EAQ85091.1 - 0.0024 17.5 0.1 0.025 14.2 0.1 2.1 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain UPF0561 PF10573.9 EAQ85091.1 - 0.016 15.3 1.8 0.15 12.2 0.1 2.9 2 0 0 2 2 2 0 Uncharacterised protein family UPF0561 Suc_Fer-like PF06999.12 EAQ85092.1 - 4e-40 137.8 0.0 4.2e-29 101.8 0.1 2.0 2 0 0 2 2 2 2 Sucrase/ferredoxin-like ASXH PF13919.6 EAQ85092.1 - 0.15 12.1 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 Asx homology domain Acyltransferase PF01553.21 EAQ85093.1 - 7.3e-09 35.3 0.0 0.00016 21.3 0.0 2.4 2 0 0 2 2 2 2 Acyltransferase BRAP2 PF07576.12 EAQ85094.1 - 3.8e-32 110.5 0.0 6.8e-32 109.6 0.0 1.4 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.19 EAQ85094.1 - 1.4e-16 60.5 9.0 4.5e-16 58.9 9.0 1.9 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.6 EAQ85094.1 - 7.5e-08 32.6 9.2 7.5e-08 32.6 9.2 1.9 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EAQ85094.1 - 9.7e-07 28.5 9.8 2.1e-06 27.4 9.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EAQ85094.1 - 2e-05 24.2 4.5 5.1e-05 22.9 4.5 1.8 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_5 PF14634.6 EAQ85094.1 - 0.00013 21.9 7.7 0.00013 21.9 7.7 2.2 2 0 0 2 2 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EAQ85094.1 - 0.00029 20.8 0.7 0.00029 20.8 0.7 2.4 1 1 0 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 EAQ85094.1 - 0.00031 21.0 6.7 0.00085 19.6 6.7 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EAQ85094.1 - 0.00037 20.3 8.3 0.00099 18.9 8.3 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EAQ85094.1 - 0.0037 17.1 6.4 0.0037 17.1 6.4 2.3 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EAQ85094.1 - 0.0099 15.7 6.6 0.0099 15.7 6.6 2.3 2 0 0 2 2 1 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 EAQ85094.1 - 0.018 14.9 3.4 0.018 14.9 3.4 1.9 2 0 0 2 2 2 0 zf-RING of BARD1-type protein STAT_int PF02865.17 EAQ85094.1 - 0.036 14.5 1.5 0.066 13.7 1.5 1.4 1 0 0 1 1 1 0 STAT protein, protein interaction domain zf-ANAPC11 PF12861.7 EAQ85094.1 - 0.078 13.0 5.9 0.22 11.6 5.9 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger SBDS_C PF09377.10 EAQ85094.1 - 0.23 11.5 0.6 0.43 10.6 0.3 1.5 1 1 0 1 1 1 0 SBDS protein C-terminal domain HeLo PF14479.6 EAQ85094.1 - 0.38 10.6 3.1 0.67 9.8 3.1 1.3 1 0 0 1 1 1 0 Prion-inhibition and propagation FlgN PF05130.12 EAQ85094.1 - 1.3 9.5 10.6 2.2 8.8 10.6 1.3 1 0 0 1 1 1 0 FlgN protein PRKG1_interact PF15898.5 EAQ85094.1 - 2.5 9.0 15.1 2.1 9.3 5.6 2.4 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain DUF5094 PF17015.5 EAQ85094.1 - 2.8 8.0 5.0 2.1 8.4 3.0 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF5094) ubiquitin PF00240.23 EAQ85095.1 - 4.4e-135 439.7 20.4 3.3e-33 113.3 0.6 4.0 4 0 0 4 4 4 4 Ubiquitin family Rad60-SLD PF11976.8 EAQ85095.1 - 6.6e-64 211.7 21.0 2e-15 56.4 0.7 4.0 4 0 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EAQ85095.1 - 8.1e-23 80.7 10.7 0.00043 20.7 0.1 5.8 4 4 0 4 4 4 4 Ubiquitin-like domain TBK1_ULD PF18396.1 EAQ85095.1 - 1.7e-16 59.9 3.0 0.027 14.4 0.0 4.2 4 0 0 4 4 4 4 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 EAQ85095.1 - 3.9e-15 56.0 8.2 0.028 14.8 0.1 4.1 4 0 0 4 4 4 4 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 EAQ85095.1 - 2.1e-14 53.6 2.6 0.12 12.4 0.0 5.0 4 4 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EAQ85095.1 - 5.6e-13 49.4 1.4 0.37 11.4 0.0 4.2 1 1 1 4 4 4 4 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 EAQ85095.1 - 5.2e-11 42.7 0.8 0.52 10.1 0.0 4.1 1 1 3 4 4 4 4 Silencing defective 2 N-terminal ubiquitin domain Ubiquitin_4 PF18036.1 EAQ85095.1 - 3.7e-07 30.1 24.0 16 5.6 0.2 8.0 8 0 0 8 8 8 0 Ubiquitin-like domain Methyltrans_RNA PF04452.14 EAQ85095.1 - 2.9e-06 26.8 0.4 1.8 7.8 0.0 3.3 3 0 0 3 3 3 3 RNA methyltransferase DUF3861 PF12977.7 EAQ85095.1 - 3.8e-06 27.0 2.5 13 6.1 0.0 4.2 4 0 0 4 4 4 0 Domain of Unknown Function with PDB structure (DUF3861) DUF2870 PF11069.8 EAQ85095.1 - 7.1e-06 26.3 0.0 30 5.1 0.0 4.6 4 0 0 4 4 4 0 Protein of unknown function (DUF2870) ACT_5 PF13710.6 EAQ85095.1 - 1.2e-05 25.0 4.7 10 6.1 0.0 4.3 4 0 0 4 4 4 0 ACT domain Big_7 PF17957.1 EAQ85095.1 - 4e-05 24.3 0.1 52 4.7 0.0 4.1 4 0 0 4 4 4 0 Bacterial Ig domain UDP-g_GGTase PF06427.11 EAQ85095.1 - 0.00014 21.9 4.3 7.1 6.8 0.0 4.0 4 0 0 4 4 4 0 UDP-glucose:Glycoprotein Glucosyltransferase DUF969 PF06149.12 EAQ85095.1 - 0.00042 19.8 0.0 23 4.3 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF969) YcgR_2 PF12945.7 EAQ85095.1 - 0.00091 19.3 6.2 29 4.9 0.1 4.3 4 0 0 4 4 4 0 Flagellar protein YcgR DUF493 PF04359.14 EAQ85095.1 - 0.003 18.1 0.1 1.4e+02 3.1 0.0 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF493) Raf1_HTH PF18579.1 EAQ85095.1 - 0.0037 16.9 0.0 1e+02 2.7 0.0 4.1 4 0 0 4 4 4 0 Rubisco accumulation factor 1 helix turn helix domain ACT_4 PF13291.6 EAQ85095.1 - 0.0052 17.4 1.0 1.4e+02 3.1 0.0 4.2 4 0 0 4 4 4 0 ACT domain ORF11CD3 PF10549.9 EAQ85095.1 - 0.0068 16.5 0.0 91 3.3 0.0 4.3 4 0 0 4 4 4 0 ORF11CD3 domain ProRS-C_2 PF09181.10 EAQ85095.1 - 0.11 12.7 5.8 1.1e+02 3.1 0.1 4.1 4 0 0 4 4 4 0 Prolyl-tRNA synthetase, C-terminal Baculo_p48 PF04878.13 EAQ85095.1 - 0.12 11.2 0.0 61 2.4 0.0 3.0 3 0 0 3 3 3 0 Baculovirus P48 protein Tash_PEST PF07708.11 EAQ85095.1 - 0.14 12.4 27.2 6.2 7.1 1.4 4.3 4 0 0 4 4 4 0 Tash protein PEST motif Myosin_N PF02736.19 EAQ85095.1 - 0.23 11.3 6.3 1.1e+02 2.8 0.0 5.2 4 0 0 4 4 4 0 Myosin N-terminal SH3-like domain HAMP_N3 PF18575.1 EAQ85095.1 - 0.23 11.0 1.5 2e+02 1.6 0.0 3.9 4 0 0 4 4 4 0 HAMP N-terminal domain 3 PI3K_p85B PF02192.16 EAQ85095.1 - 1.9 8.3 9.3 96 2.8 0.1 4.2 4 0 0 4 4 4 0 PI3-kinase family, p85-binding domain Zn_clus PF00172.18 EAQ85096.1 - 0.0039 17.3 7.7 0.0081 16.3 7.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Prenyltrans PF00432.21 EAQ85097.1 - 4.1e-31 106.4 24.7 1.3e-09 37.6 0.5 6.4 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 EAQ85097.1 - 0.027 13.6 0.1 0.11 11.6 0.3 1.8 2 0 0 2 2 2 0 Squalene-hopene cyclase C-terminal domain NTP_transferase PF00483.23 EAQ85100.1 - 2.3e-53 181.3 0.0 4.7e-53 180.3 0.0 1.5 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.24 EAQ85100.1 - 4.4e-16 57.9 11.5 4e-10 39.0 1.5 4.1 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 EAQ85100.1 - 3.2e-10 40.6 0.0 4.2e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 EAQ85100.1 - 8.4e-06 25.4 2.9 8.4e-06 25.4 2.9 3.4 3 2 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 EAQ85100.1 - 0.00034 18.9 0.1 0.0011 17.3 0.0 1.7 1 1 1 2 2 2 1 Domain of unknown function (DUF4954) FGGY_C PF02782.16 EAQ85101.1 - 7e-75 251.1 0.3 1.3e-74 250.2 0.3 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 EAQ85101.1 - 4.3e-53 180.4 0.0 6.2e-53 179.9 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain Pkinase PF00069.25 EAQ85102.1 - 8.6e-24 84.3 0.0 1.4e-23 83.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ85102.1 - 1.1e-15 57.6 0.0 1.2e-14 54.2 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAQ85102.1 - 0.0048 16.3 0.0 0.0068 15.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Glyco_hydro_81 PF03639.13 EAQ85103.1 - 5.1e-90 301.9 0.0 3.1e-86 289.5 0.0 2.2 1 1 1 2 2 2 2 Glycosyl hydrolase family 81 N-terminal domain Glyco_hydro81C PF17652.1 EAQ85103.1 - 2.3e-73 247.5 3.4 5.5e-35 121.2 0.4 3.1 1 1 2 3 3 3 3 Glycosyl hydrolase family 81 C-terminal domain Tfb5 PF06331.12 EAQ85103.1 - 0.19 11.7 0.0 0.32 11.0 0.0 1.3 1 0 0 1 1 1 0 Transcription factor TFIIH complex subunit Tfb5 Stn1 PF10451.9 EAQ85104.1 - 9.4e-15 54.3 0.5 1.8e-08 33.7 0.0 2.1 2 0 0 2 2 2 2 Telomere regulation protein Stn1 tRNA_anti-codon PF01336.25 EAQ85104.1 - 1.8e-06 27.8 0.2 5.7e-06 26.2 0.2 1.8 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain RMI2 PF16100.5 EAQ85104.1 - 0.0016 18.3 0.1 0.064 13.1 0.1 2.3 1 1 0 1 1 1 1 RecQ-mediated genome instability protein 2 DnaJ PF00226.31 EAQ85105.1 - 3.5e-24 84.7 3.8 4e-24 84.5 1.6 2.3 2 0 0 2 2 2 1 DnaJ domain Nif11 PF07862.11 EAQ85105.1 - 0.0048 17.2 3.6 0.38 11.1 0.0 3.1 2 1 0 2 2 2 1 Nif11 domain SIMPL PF04402.14 EAQ85105.1 - 0.66 10.4 8.4 0.9 10.0 8.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF541) Inv-AAD PF18785.1 EAQ85106.1 - 1.4e-61 206.0 0.2 1.6e-61 205.8 0.2 1.0 1 0 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase dCMP_cyt_deam_1 PF00383.23 EAQ85106.1 - 1.5e-14 53.6 0.0 2.3e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EAQ85106.1 - 0.00097 18.9 0.0 0.0015 18.3 0.0 1.5 1 1 0 1 1 1 1 MafB19-like deaminase MR_MLE_C PF13378.6 EAQ85108.1 - 2e-58 197.6 0.0 3e-58 197.0 0.0 1.2 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 EAQ85108.1 - 0.0011 19.1 0.0 0.0028 17.9 0.0 1.6 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MAAL_C PF07476.11 EAQ85108.1 - 0.0085 15.3 0.0 0.015 14.5 0.0 1.3 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus DUF2517 PF10725.9 EAQ85108.1 - 0.18 11.6 0.6 0.33 10.7 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2517) Rad10 PF03834.14 EAQ85110.1 - 2.3e-44 150.0 0.0 3.2e-44 149.6 0.0 1.2 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) Glyco_hydro_47 PF01532.20 EAQ85111.1 - 2e-146 488.5 0.0 2.2e-146 488.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF5384 PF17358.2 EAQ85112.1 - 0.015 15.3 6.0 0.018 15.1 6.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5384) DEAD PF00270.29 EAQ85113.1 - 4.4e-41 140.6 0.1 6.5e-41 140.0 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EAQ85113.1 - 2e-10 41.0 0.4 1.8e-09 37.9 0.4 2.6 2 1 0 2 2 2 1 Helicase conserved C-terminal domain GST_C PF00043.25 EAQ85113.1 - 3.5e-08 33.5 0.0 3e-07 30.5 0.0 2.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EAQ85113.1 - 1.5e-07 31.6 0.0 5.2e-07 29.9 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EAQ85113.1 - 7.5e-06 26.2 0.0 1.6e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain ResIII PF04851.15 EAQ85113.1 - 8e-06 26.0 0.0 1.7e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit GST_N_3 PF13417.6 EAQ85113.1 - 8.9e-06 26.0 0.0 2.2e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EAQ85113.1 - 3.4e-05 23.8 0.1 8.7e-05 22.5 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EAQ85113.1 - 0.00074 19.7 0.0 0.003 17.7 0.0 2.0 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain RRM_1 PF00076.22 EAQ85114.1 - 4.9e-21 74.3 0.1 3.8e-09 36.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 EAQ85114.1 - 0.02 14.9 0.0 0.04 14.0 0.0 1.4 1 0 0 1 1 1 0 RNA binding motif PXA PF02194.15 EAQ85115.1 - 4.4e-51 173.5 0.7 4.4e-51 173.5 0.7 2.4 3 0 0 3 3 3 1 PXA domain PX PF00787.24 EAQ85115.1 - 6.4e-16 58.3 2.5 1.8e-15 56.9 2.5 1.8 1 0 0 1 1 1 1 PX domain Nexin_C PF08628.12 EAQ85115.1 - 2e-14 54.1 0.0 1.1e-13 51.7 0.0 2.3 2 0 0 2 2 2 1 Sorting nexin C terminal RGS PF00615.19 EAQ85115.1 - 2.6e-06 27.7 0.0 8.5e-06 26.0 0.0 2.0 1 0 0 1 1 1 1 Regulator of G protein signaling domain Wzy_C_2 PF11846.8 EAQ85115.1 - 0.018 15.0 0.1 0.043 13.7 0.1 1.6 1 0 0 1 1 1 0 Virulence factor membrane-bound polymerase, C-terminal ABC_tran_CTD PF16326.5 EAQ85115.1 - 0.25 11.6 2.2 0.95 9.8 2.2 2.0 1 0 0 1 1 1 0 ABC transporter C-terminal domain OrsD PF12013.8 EAQ85116.1 - 4.3e-31 107.7 2.5 3.7e-30 104.7 0.2 2.9 3 0 0 3 3 3 1 Orsellinic acid/F9775 biosynthesis cluster protein D DUF4351 PF14261.6 EAQ85116.1 - 0.12 12.5 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4351) zf-C2H2_4 PF13894.6 EAQ85116.1 - 0.45 11.5 4.8 18 6.5 0.2 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger ADH_zinc_N PF00107.26 EAQ85117.1 - 1.1e-10 41.6 0.2 2.8e-10 40.3 0.2 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Fructosamin_kin PF03881.14 EAQ85117.1 - 2e-10 40.4 0.0 2.8e-10 39.9 0.0 1.1 1 0 0 1 1 1 1 Fructosamine kinase ADH_N PF08240.12 EAQ85117.1 - 9.2e-09 35.2 0.5 3.9e-08 33.2 0.5 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain SM-ATX PF14438.6 EAQ85117.1 - 0.028 14.5 0.0 0.086 13.0 0.0 1.8 1 0 0 1 1 1 0 Ataxin 2 SM domain ADH_zinc_N_2 PF13602.6 EAQ85117.1 - 0.12 13.5 0.0 0.42 11.7 0.0 2.0 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Hydrolase_4 PF12146.8 EAQ85118.1 - 0.0018 17.6 0.0 0.026 13.8 0.0 2.5 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EAQ85118.1 - 0.0023 18.5 0.0 0.0034 18.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family AstA PF04958.12 EAQ85118.1 - 0.082 11.4 0.0 0.12 10.9 0.0 1.2 1 0 0 1 1 1 0 Arginine N-succinyltransferase beta subunit RTT107_BRCT_5 PF16770.5 EAQ85119.1 - 1.4e-32 111.5 0.0 3.6e-31 107.0 0.0 3.1 3 0 0 3 3 3 1 Regulator of Ty1 transposition protein 107 BRCT domain PTCB-BRCT PF12738.7 EAQ85119.1 - 2.5e-29 101.0 1.6 5.5e-19 67.9 0.2 4.8 5 1 0 5 5 5 3 twin BRCT domain BRCT PF00533.26 EAQ85119.1 - 1.6e-27 95.7 0.1 2.2e-08 34.4 0.0 5.8 6 0 0 6 6 6 4 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 EAQ85119.1 - 8e-26 90.3 0.0 9.3e-05 22.8 0.0 5.6 6 0 0 6 6 6 5 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 EAQ85119.1 - 7.9e-11 42.1 0.3 0.026 14.8 0.0 3.9 3 0 0 3 3 3 3 DNA ligase 3 BRCT domain BRCT_3 PF18428.1 EAQ85119.1 - 0.015 15.3 0.0 2.5 8.2 0.0 3.3 3 0 0 3 3 3 0 BRCA1 C Terminus (BRCT) domain HMG_CoA_synt_N PF01154.17 EAQ85120.1 - 6.2e-96 319.3 0.8 6.2e-96 319.3 0.8 1.5 2 0 0 2 2 2 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal HMG_CoA_synt_C PF08540.10 EAQ85120.1 - 2.5e-93 312.7 0.8 8.1e-92 307.8 0.8 2.3 1 1 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal BCS1_N PF08740.11 EAQ85121.1 - 5.6e-56 189.5 0.8 5.6e-56 189.5 0.8 2.7 2 1 0 2 2 1 1 BCS1 N terminal AAA PF00004.29 EAQ85121.1 - 3.7e-09 37.1 0.0 8.8e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TFIIF_alpha PF05793.12 EAQ85121.1 - 6.8e-05 21.6 38.0 6.8e-05 21.6 38.0 2.4 4 0 0 4 4 4 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) RuvB_N PF05496.12 EAQ85121.1 - 0.0014 18.4 0.0 0.0024 17.6 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 EAQ85121.1 - 0.0014 18.6 0.0 0.0048 16.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 EAQ85121.1 - 0.0018 17.9 0.0 0.0041 16.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 EAQ85121.1 - 0.089 12.9 0.0 0.26 11.4 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.6 EAQ85121.1 - 0.094 13.0 0.0 0.27 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain PPV_E1_C PF00519.17 EAQ85121.1 - 0.099 11.5 0.0 0.21 10.4 0.0 1.4 1 0 0 1 1 1 0 Papillomavirus helicase DUF3342 PF11822.8 EAQ85121.1 - 0.19 11.9 0.0 0.4 10.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3342) AAA_21 PF13304.6 EAQ85121.1 - 0.29 10.9 3.1 2 8.1 0.0 2.6 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EAQ85121.1 - 0.34 11.3 7.5 0.66 10.3 6.8 2.2 1 1 0 1 1 1 0 AAA ATPase domain Macoilin PF09726.9 EAQ85121.1 - 0.37 9.3 19.5 0.53 8.8 19.5 1.2 1 0 0 1 1 1 0 Macoilin family AAA_13 PF13166.6 EAQ85121.1 - 0.38 9.4 22.7 3.8 6.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain GREB1 PF15782.5 EAQ85121.1 - 0.73 6.9 15.5 1.1 6.3 15.5 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer NOA36 PF06524.12 EAQ85122.1 - 1.8 7.8 5.9 2.6 7.3 5.9 1.2 1 0 0 1 1 1 0 NOA36 protein G_path_suppress PF15991.5 EAQ85122.1 - 6.1 6.9 7.3 8.3 6.4 7.3 1.1 1 0 0 1 1 1 0 G-protein pathway suppressor DUF3328 PF11807.8 EAQ85123.1 - 0.19 11.5 1.7 0.67 9.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3328) Methyltransf_23 PF13489.6 EAQ85125.1 - 3.5e-21 75.7 0.0 5.5e-21 75.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EAQ85125.1 - 5e-18 65.6 0.0 7.3e-18 65.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAQ85125.1 - 1.8e-14 54.2 0.0 3.1e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EAQ85125.1 - 1.1e-12 48.6 0.0 1.6e-12 48.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAQ85125.1 - 2e-12 47.2 0.0 2.9e-12 46.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EAQ85125.1 - 3.5e-05 23.3 0.0 4.9e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.20 EAQ85125.1 - 0.00063 19.1 0.0 0.0013 18.1 0.0 1.5 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.11 EAQ85125.1 - 0.001 18.1 0.0 0.0014 17.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MTS PF05175.14 EAQ85125.1 - 0.0053 16.3 0.0 0.0085 15.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain DHBP_synthase PF00926.19 EAQ85126.1 - 8.3e-83 276.6 0.0 9.6e-83 276.4 0.0 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase Utp14 PF04615.13 EAQ85127.1 - 2.1e-188 628.5 57.0 2.1e-188 628.5 57.0 2.7 1 1 1 2 2 2 1 Utp14 protein MRP-L27 PF09809.9 EAQ85128.1 - 8.9e-19 67.4 0.5 1.1e-18 67.1 0.5 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 Abhydrolase_3 PF07859.13 EAQ85129.1 - 1.3e-39 136.3 0.1 1.3e-29 103.6 0.1 2.6 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EAQ85129.1 - 1.6e-12 47.0 0.0 6.5e-12 45.0 0.0 1.8 2 0 0 2 2 2 1 Steryl acetyl hydrolase COesterase PF00135.28 EAQ85129.1 - 0.0049 15.8 0.1 0.17 10.7 0.0 2.1 2 0 0 2 2 2 1 Carboxylesterase family Abhydrolase_2 PF02230.16 EAQ85129.1 - 0.066 13.0 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase OGFr_III PF04680.13 EAQ85129.1 - 0.13 12.9 1.6 0.72 10.5 0.3 3.1 2 0 0 2 2 2 0 Opioid growth factor receptor repeat TT_ORF2 PF02957.15 EAQ85129.1 - 5.7 7.9 6.0 1.1 10.1 0.9 2.4 2 0 0 2 2 2 0 TT viral ORF2 zf-RING_2 PF13639.6 EAQ85130.1 - 1.6e-09 37.9 5.9 2.4e-09 37.4 5.9 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 EAQ85130.1 - 1.5e-06 28.4 5.6 4.5e-06 26.9 5.6 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 EAQ85130.1 - 9.4e-05 22.4 1.2 0.00016 21.7 1.2 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 EAQ85130.1 - 0.0001 22.1 3.2 0.00019 21.2 3.2 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EAQ85130.1 - 0.00031 20.5 5.5 0.00085 19.1 5.7 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EAQ85130.1 - 0.00039 20.4 5.2 0.0007 19.6 5.2 1.4 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 EAQ85130.1 - 0.0032 17.3 1.9 0.81 9.6 0.4 2.4 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 EAQ85130.1 - 0.0095 15.8 3.6 0.017 15.0 3.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) YacG PF03884.14 EAQ85130.1 - 0.095 12.5 0.5 13 5.6 0.1 3.3 3 0 0 3 3 3 0 DNA gyrase inhibitor YacG Zn-C2H2_12 PF18112.1 EAQ85130.1 - 0.2 12.1 6.3 1.5 9.3 0.1 3.0 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain Tmpp129 PF10272.9 EAQ85130.1 - 0.25 10.6 0.2 0.25 10.6 0.2 1.5 2 0 0 2 2 2 0 Putative transmembrane protein precursor zf-Di19 PF05605.12 EAQ85130.1 - 0.3 11.4 3.9 16 5.9 0.1 2.7 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-RING_5 PF14634.6 EAQ85130.1 - 0.31 11.0 3.9 0.86 9.6 4.0 1.7 1 1 0 1 1 1 0 zinc-RING finger domain zf-RING_4 PF14570.6 EAQ85130.1 - 0.39 10.5 6.7 8.3 6.3 7.4 2.2 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 EAQ85130.1 - 1.1 9.0 5.6 0.8 9.5 2.7 2.1 2 0 0 2 2 2 0 RING-like zinc finger zf-C3HC4_5 PF17121.5 EAQ85130.1 - 2.3 8.2 8.1 8.4 6.4 8.1 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.12 EAQ85130.1 - 2.7 7.3 4.7 2.7 7.3 2.4 2.1 2 1 0 2 2 2 0 Rtf2 RING-finger Pkinase PF00069.25 EAQ85131.1 - 1.8e-14 53.7 0.0 2.8e-14 53.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ85131.1 - 5.7e-06 25.8 0.0 9e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Apc15p PF05841.11 EAQ85131.1 - 0.052 14.4 1.2 0.1 13.4 1.2 1.5 1 0 0 1 1 1 0 Apc15p protein PAP1 PF08601.10 EAQ85132.1 - 8.4e-56 190.3 34.9 1e-45 157.1 2.1 3.1 1 1 2 3 3 3 2 Transcription factor PAP1 CENP-H PF05837.12 EAQ85132.1 - 0.096 13.1 2.8 0.2 12.1 2.8 1.5 1 0 0 1 1 1 0 Centromere protein H (CENP-H) DUF1664 PF07889.12 EAQ85132.1 - 0.13 12.3 2.3 0.27 11.3 2.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Seryl_tRNA_N PF02403.22 EAQ85132.1 - 0.19 12.0 5.4 0.14 12.4 2.0 2.1 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain STAC2_u1 PF16664.5 EAQ85132.1 - 3.3 8.2 10.4 0.34 11.4 1.8 2.5 1 1 1 2 2 2 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 BSD PF03909.17 EAQ85133.1 - 1.9e-20 72.6 0.1 4e-20 71.6 0.1 1.6 1 0 0 1 1 1 1 BSD domain Sigma70_r2 PF04542.14 EAQ85133.1 - 0.1 12.4 0.1 0.35 10.7 0.1 1.9 1 0 0 1 1 1 0 Sigma-70 region 2 DUF1682 PF07946.14 EAQ85133.1 - 0.25 10.5 13.4 0.45 9.7 13.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) F-protein PF00469.20 EAQ85133.1 - 0.83 9.2 13.1 2.3 7.8 13.1 1.8 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef WGG PF10273.9 EAQ85134.1 - 2.2e-35 121.1 0.2 3.4e-35 120.6 0.2 1.3 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 RRP7 PF12923.7 EAQ85134.1 - 0.051 13.7 0.1 0.051 13.7 0.1 2.4 2 1 1 3 3 3 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain NOA36 PF06524.12 EAQ85134.1 - 2.4 7.4 7.8 3.5 6.9 7.8 1.2 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 EAQ85134.1 - 8.1 4.4 12.1 11 4.0 12.1 1.2 1 0 0 1 1 1 0 DNA polymerase phi Flavokinase PF01687.17 EAQ85135.1 - 5.6e-34 116.8 0.0 1.1e-33 115.8 0.0 1.5 1 0 0 1 1 1 1 Riboflavin kinase Epimerase PF01370.21 EAQ85135.1 - 3e-07 30.1 0.0 4.4e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EAQ85135.1 - 5.8e-06 26.3 0.1 1.1e-05 25.4 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding HIM1 PF08732.10 EAQ85135.1 - 0.0013 18.3 0.0 0.0019 17.7 0.0 1.2 1 0 0 1 1 1 1 HIM1 NmrA PF05368.13 EAQ85135.1 - 0.044 13.3 0.3 0.46 10.0 0.0 2.1 2 0 0 2 2 2 0 NmrA-like family PAS PF00989.25 EAQ85136.1 - 0.00022 21.2 0.0 0.00055 19.9 0.0 1.7 1 0 0 1 1 1 1 PAS fold Zn_clus PF00172.18 EAQ85136.1 - 0.0024 18.0 9.4 0.0057 16.8 9.4 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 EAQ85137.1 - 1.2e-34 119.8 27.0 5e-34 117.8 22.6 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EAQ85137.1 - 3.5e-07 29.1 2.5 5.6e-07 28.4 2.5 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) UL41A PF17591.2 EAQ85137.1 - 0.68 10.1 1.9 2.8 8.1 0.0 2.5 2 0 0 2 2 2 0 Herpesvirus UL41A Cellulase PF00150.18 EAQ85139.1 - 3.5e-10 39.8 0.0 5.3e-10 39.2 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) PsaX PF08078.12 EAQ85139.1 - 0.48 10.4 4.2 0.89 9.6 0.0 2.3 2 0 0 2 2 2 0 PsaX family Synaptobrevin PF00957.21 EAQ85139.1 - 1.2 9.0 3.4 2 8.3 3.4 1.3 1 0 0 1 1 1 0 Synaptobrevin Synaphin PF05835.12 EAQ85139.1 - 4.7 7.5 20.8 9.9 6.4 20.8 1.4 1 0 0 1 1 1 0 Synaphin protein PNISR PF15996.5 EAQ85139.1 - 8.8 6.5 12.5 61 3.8 10.9 2.1 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR Transket_pyr PF02779.24 EAQ85140.1 - 2e-42 144.9 0.0 3.4e-42 144.1 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EAQ85140.1 - 1.9e-33 115.0 0.1 3.2e-33 114.2 0.1 1.4 1 0 0 1 1 1 1 Transketolase, C-terminal domain PFOR_II PF17147.4 EAQ85140.1 - 0.00075 19.8 0.0 0.0013 19.0 0.0 1.4 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II Cyt-b5 PF00173.28 EAQ85141.1 - 3.3e-22 78.4 0.2 4.4e-22 78.0 0.2 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain YqzH PF14164.6 EAQ85141.1 - 0.0096 16.0 0.6 0.022 14.8 0.6 1.6 1 0 0 1 1 1 1 YqzH-like protein TFA2_Winged_2 PF18121.1 EAQ85142.1 - 1.5e-22 79.0 0.1 2.6e-22 78.3 0.1 1.4 1 0 0 1 1 1 1 TFA2 Winged helix domain 2 TFIIE_beta PF02186.15 EAQ85142.1 - 5.9e-07 29.7 0.0 1.9e-06 28.1 0.0 1.8 2 0 0 2 2 2 1 TFIIE beta subunit core domain Dermcidin PF15291.6 EAQ85142.1 - 0.075 13.6 0.4 0.075 13.6 0.4 2.4 3 0 0 3 3 3 0 Dermcidin, antibiotic peptide DUF1611 PF07755.11 EAQ85142.1 - 0.17 11.2 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1611_C) P-loop domain DSBA PF01323.20 EAQ85143.1 - 1.3e-16 61.0 0.0 1.6e-16 60.6 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Ank_5 PF13857.6 EAQ85144.1 - 5.3e-22 77.6 6.8 2.6e-06 27.6 0.0 4.7 4 0 0 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAQ85144.1 - 2.1e-21 76.3 0.0 1e-05 26.0 0.0 4.2 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAQ85144.1 - 6.4e-19 68.1 1.4 0.015 15.9 0.0 5.3 4 2 2 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 EAQ85144.1 - 6.6e-17 61.1 7.9 2.4e-07 30.9 0.3 5.5 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 EAQ85144.1 - 1.3e-14 52.9 7.2 9.6e-07 28.7 0.0 7.5 8 0 0 8 8 8 2 Ankyrin repeat zf-C2H2 PF00096.26 EAQ85146.1 - 3.5e-22 77.5 25.5 7.5e-06 26.1 0.2 4.4 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EAQ85146.1 - 5.7e-15 55.0 27.8 1.7e-06 28.2 1.2 4.7 5 0 0 5 5 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 EAQ85146.1 - 1.8e-12 47.0 22.7 0.0028 18.4 1.5 4.4 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EAQ85146.1 - 1.2e-05 25.4 0.1 3 8.2 0.0 4.3 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 EAQ85146.1 - 0.00014 21.5 7.0 0.0016 18.2 0.4 3.1 3 0 0 3 3 3 1 zinc-finger C2H2-type zf_UBZ PF18439.1 EAQ85146.1 - 0.00099 18.7 2.7 0.7 9.5 0.2 3.0 3 0 0 3 3 2 2 Ubiquitin-Binding Zinc Finger zf-met PF12874.7 EAQ85146.1 - 0.0034 17.7 8.5 6.8 7.2 0.0 4.2 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf_C2H2_13 PF18508.1 EAQ85146.1 - 0.035 13.7 0.8 3.5 7.3 0.0 2.5 2 0 0 2 2 2 0 Zinc finger domain zf-C2H2_aberr PF17017.5 EAQ85146.1 - 0.039 14.1 1.1 4.7 7.3 0.2 2.2 2 0 0 2 2 2 0 Aberrant zinc-finger IBR PF01485.21 EAQ85146.1 - 0.15 12.3 5.5 11 6.3 0.6 3.1 2 1 1 3 3 3 0 IBR domain, a half RING-finger domain zf-TRAF PF02176.18 EAQ85146.1 - 0.63 10.8 9.3 0.96 10.2 0.5 2.3 2 0 0 2 2 2 0 TRAF-type zinc finger DUF2256 PF10013.9 EAQ85146.1 - 1.3 9.2 10.0 2.7 8.2 0.2 3.6 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2256) Zn-ribbon_8 PF09723.10 EAQ85146.1 - 1.3 9.2 8.7 5.1 7.3 1.7 3.1 1 1 1 3 3 3 0 Zinc ribbon domain LIM PF00412.22 EAQ85146.1 - 1.4 9.2 5.5 17 5.8 0.1 3.0 1 1 2 3 3 3 0 LIM domain zf-CRD PF17979.1 EAQ85146.1 - 1.5 8.9 7.7 6.4 6.9 1.5 2.2 1 1 1 2 2 2 0 Cysteine rich domain with multizinc binding regions XPA_N PF01286.18 EAQ85146.1 - 2 8.6 8.7 0.65 10.1 0.5 3.1 4 0 0 4 4 3 0 XPA protein N-terminal HNH PF01844.23 EAQ85146.1 - 2.1 8.6 8.4 7.9 6.7 0.1 3.9 4 0 0 4 4 4 0 HNH endonuclease DZR PF12773.7 EAQ85146.1 - 2.3 8.3 7.1 34 4.6 7.1 2.4 1 1 0 1 1 1 0 Double zinc ribbon ADK_lid PF05191.14 EAQ85146.1 - 3.9 7.5 9.5 2.4 8.2 0.1 3.5 3 1 1 4 4 4 0 Adenylate kinase, active site lid Ogr_Delta PF04606.12 EAQ85146.1 - 4.5 7.3 9.1 12 5.9 0.3 2.4 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger FOXP-CC PF16159.5 EAQ85146.1 - 6.8 7.4 10.0 10 6.9 0.1 3.6 3 1 1 4 4 4 0 FOXP coiled-coil domain Na_Ca_ex PF01699.24 EAQ85147.1 - 1.7e-39 135.2 28.0 6.8e-22 78.0 16.0 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Patatin PF01734.22 EAQ85148.1 - 3.6e-39 135.1 0.0 6.2e-39 134.3 0.0 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase HeLo PF14479.6 EAQ85149.1 - 8.8e-45 153.1 0.0 1.4e-44 152.4 0.0 1.3 1 0 0 1 1 1 1 Prion-inhibition and propagation PAXNEB PF05625.11 EAQ85149.1 - 0.07 12.3 2.8 0.22 10.6 0.6 2.0 1 1 1 2 2 2 0 PAXNEB protein FAD_binding_4 PF01565.23 EAQ85150.1 - 1.2e-13 51.0 0.0 1.2e-13 51.0 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain Abhydrolase_3 PF07859.13 EAQ85151.1 - 1e-37 130.1 1.2 4.3e-37 128.0 1.2 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EAQ85151.1 - 0.00016 20.7 0.5 0.0021 17.0 0.5 2.4 1 1 0 1 1 1 1 Steryl acetyl hydrolase Pex14_N PF04695.13 EAQ85152.1 - 2.4e-40 138.8 1.5 2.4e-40 138.8 1.5 2.8 2 1 1 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1978 PF09321.10 EAQ85152.1 - 0.0014 18.0 5.1 0.002 17.5 5.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1978) ERM PF00769.19 EAQ85152.1 - 0.002 18.0 3.2 0.0031 17.4 3.2 1.3 1 0 0 1 1 1 1 Ezrin/radixin/moesin family zf-C4H2 PF10146.9 EAQ85152.1 - 0.0042 17.4 5.9 0.0042 17.4 5.9 2.4 2 1 0 2 2 2 1 Zinc finger-containing protein Golgin_A5 PF09787.9 EAQ85152.1 - 0.0051 16.3 5.8 0.0075 15.8 5.8 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 5 CR6_interact PF10147.9 EAQ85152.1 - 0.0088 15.8 0.2 0.015 15.0 0.2 1.3 1 0 0 1 1 1 1 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 DUF1043 PF06295.12 EAQ85152.1 - 0.01 15.8 4.6 0.021 14.8 4.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1043) DUF16 PF01519.16 EAQ85152.1 - 0.013 16.0 2.2 1.6 9.2 1.1 2.3 2 0 0 2 2 2 0 Protein of unknown function DUF16 DUF3584 PF12128.8 EAQ85152.1 - 0.04 11.5 10.3 0.051 11.1 10.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) tRNA-synt_His PF13393.6 EAQ85152.1 - 0.04 13.2 1.4 0.22 10.8 0.0 2.1 1 1 1 2 2 2 0 Histidyl-tRNA synthetase Prominin PF05478.11 EAQ85152.1 - 0.046 11.7 1.5 0.062 11.2 1.5 1.2 1 0 0 1 1 1 0 Prominin HLH PF00010.26 EAQ85152.1 - 0.064 13.2 0.9 12 5.9 0.7 3.0 2 1 0 2 2 2 0 Helix-loop-helix DNA-binding domain DUF2939 PF11159.8 EAQ85152.1 - 0.065 13.7 0.5 0.065 13.7 0.5 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2939) UPF0242 PF06785.11 EAQ85152.1 - 0.077 13.1 4.1 0.12 12.5 4.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus 5_nucleotid PF05761.14 EAQ85152.1 - 0.08 11.8 2.7 0.11 11.4 2.7 1.1 1 0 0 1 1 1 0 5' nucleotidase family RasGAP_C PF03836.15 EAQ85152.1 - 0.17 12.0 2.1 2 8.6 0.0 2.2 1 1 1 2 2 2 0 RasGAP C-terminus SlyX PF04102.12 EAQ85152.1 - 0.27 11.9 4.2 0.53 10.9 2.8 2.4 1 1 1 2 2 2 0 SlyX Apolipoprotein PF01442.18 EAQ85152.1 - 0.77 9.6 13.0 2.8 7.8 13.0 1.8 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.12 EAQ85152.1 - 0.8 9.7 9.2 3.6 7.6 0.8 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus TMPIT PF07851.13 EAQ85152.1 - 1 8.6 2.7 1.5 8.0 2.7 1.3 1 0 0 1 1 1 0 TMPIT-like protein FliD_N PF02465.18 EAQ85152.1 - 2.1 9.1 6.4 1.9e+02 2.8 6.4 3.0 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus Spc7 PF08317.11 EAQ85152.1 - 2.7 6.8 9.6 4.4 6.1 9.6 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4407 PF14362.6 EAQ85152.1 - 6 6.1 8.8 8.6 5.6 8.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HAUS-augmin3 PF14932.6 EAQ85152.1 - 6.1 6.4 9.2 4.8 6.7 6.1 1.9 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 Ndc80_HEC PF03801.13 EAQ85153.1 - 1.1e-61 207.0 0.5 2.2e-61 205.9 0.5 1.6 1 0 0 1 1 1 1 HEC/Ndc80p family Spc7 PF08317.11 EAQ85153.1 - 1.1e-05 24.6 39.0 7.8e-05 21.7 9.0 3.1 3 0 0 3 3 3 2 Spc7 kinetochore protein DHR10 PF18595.1 EAQ85153.1 - 0.0025 17.8 15.9 0.0025 17.8 15.9 3.9 2 2 1 3 3 3 1 Designed helical repeat protein 10 domain TPR_MLP1_2 PF07926.12 EAQ85153.1 - 0.0028 17.7 12.7 0.0028 17.7 12.7 3.7 3 1 0 3 3 3 1 TPR/MLP1/MLP2-like protein DUF1664 PF07889.12 EAQ85153.1 - 0.014 15.4 0.7 0.014 15.4 0.7 4.7 2 2 3 5 5 5 0 Protein of unknown function (DUF1664) ABC_tran_CTD PF16326.5 EAQ85153.1 - 0.021 15.0 52.3 0.55 10.5 3.7 5.5 3 1 3 6 6 6 0 ABC transporter C-terminal domain DUF3584 PF12128.8 EAQ85153.1 - 0.22 9.0 37.6 0.2 9.1 13.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Lebercilin PF15619.6 EAQ85153.1 - 0.32 10.6 40.0 0.075 12.7 10.6 3.6 3 0 0 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease AAA_23 PF13476.6 EAQ85153.1 - 0.9 10.0 18.1 4.5 7.7 7.2 2.7 2 0 0 2 2 2 0 AAA domain WASH_WAHD PF11945.8 EAQ85153.1 - 1.3 8.4 15.4 0.014 15.0 4.4 2.6 3 0 0 3 3 3 0 WAHD domain of WASH complex APG6_N PF17675.1 EAQ85153.1 - 2.9 8.4 56.2 1 9.9 13.7 4.5 2 1 1 4 4 4 0 Apg6 coiled-coil region Fez1 PF06818.15 EAQ85153.1 - 4.9 7.5 40.3 3.2 8.2 6.7 3.3 2 1 1 3 3 3 0 Fez1 Fungal_TACC PF12709.7 EAQ85153.1 - 7.1 7.2 25.8 0.93 10.0 0.1 5.7 3 2 2 5 5 4 0 Fungal Transforming acidic coiled-coil (TACC) proteins Prefoldin PF02996.17 EAQ85153.1 - 8.1 6.4 27.8 5.1 7.0 1.0 5.0 4 1 0 4 4 4 0 Prefoldin subunit FlaC_arch PF05377.11 EAQ85153.1 - 8.3 6.9 27.5 3.3 8.2 0.3 6.1 6 0 0 6 6 6 0 Flagella accessory protein C (FlaC) Cauli_AT PF03233.13 EAQ85153.1 - 9.6 6.1 14.1 0.33 10.9 2.0 3.2 2 1 1 3 3 3 0 Aphid transmission protein DUF4407 PF14362.6 EAQ85153.1 - 9.9 5.4 34.1 4.3 6.6 12.6 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) Methyltransf_4 PF02390.17 EAQ85154.1 - 1.2e-53 181.1 0.0 1.6e-53 180.7 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 EAQ85154.1 - 0.00012 22.7 0.0 0.0005 20.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAQ85154.1 - 0.003 17.4 0.1 0.0073 16.1 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 EAQ85154.1 - 0.016 14.8 0.0 0.033 13.7 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_12 PF08242.12 EAQ85154.1 - 0.019 15.7 0.0 0.044 14.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 EAQ85154.1 - 0.091 13.4 0.0 0.35 11.6 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Homoserine_dh PF00742.19 EAQ85155.1 - 8.4e-52 175.6 0.0 1.1e-51 175.1 0.0 1.2 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 EAQ85155.1 - 4.1e-19 69.4 0.0 7.2e-19 68.6 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DUF4078 PF13300.6 EAQ85156.1 - 2.2e-26 92.0 16.5 2.2e-26 92.0 16.5 2.5 2 1 1 3 3 3 1 Domain of unknown function (DUF4078) TBD PF12845.7 EAQ85156.1 - 0.067 13.1 0.1 0.27 11.1 0.1 2.1 1 0 0 1 1 1 0 TBD domain DUF903 PF06004.12 EAQ85156.1 - 0.11 12.4 0.7 2.6 8.0 0.1 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF903) Cwf_Cwc_15 PF04889.12 EAQ85156.1 - 2.2 8.0 25.6 0.12 12.1 10.7 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein FAM75 PF14650.6 EAQ85156.1 - 2.8 7.4 9.6 0.087 12.4 2.7 1.9 2 0 0 2 2 2 0 FAM75 family Cupin_2 PF07883.11 EAQ85160.1 - 3.1e-13 49.2 0.1 4.8e-13 48.6 0.1 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 EAQ85160.1 - 7e-07 29.0 0.0 1.1e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.19 EAQ85160.1 - 1.8e-05 24.6 0.0 3e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_3 PF05899.12 EAQ85160.1 - 0.0054 16.4 0.0 0.0095 15.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF861) EutQ PF06249.12 EAQ85160.1 - 0.12 12.2 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutQ Glyco_hydro_7 PF00840.20 EAQ85161.1 - 9e-106 354.2 15.4 1e-105 354.0 15.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Glyco_hydro_7 PF00840.20 EAQ85162.1 - 1.7e-28 99.6 0.0 1.8e-28 99.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 zf-Nse PF11789.8 EAQ85163.1 - 9.6e-21 73.4 0.8 1.8e-20 72.5 0.8 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-MIZ PF02891.20 EAQ85163.1 - 5.2e-05 22.9 0.5 9.5e-05 22.1 0.5 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-C3HC4_2 PF13923.6 EAQ85163.1 - 0.0017 18.2 1.3 0.0029 17.4 1.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EAQ85163.1 - 0.0018 18.2 0.1 0.0048 16.9 0.0 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 EAQ85163.1 - 0.0076 16.3 0.1 0.017 15.1 0.1 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger CCT_2 PF09425.10 EAQ85163.1 - 0.045 13.6 1.2 0.15 12.0 1.2 1.9 1 0 0 1 1 1 0 Divergent CCT motif U-box PF04564.15 EAQ85163.1 - 0.05 13.8 0.0 0.1 12.8 0.0 1.4 1 0 0 1 1 1 0 U-box domain zf-RING_2 PF13639.6 EAQ85163.1 - 0.067 13.5 0.6 0.13 12.6 0.6 1.5 1 0 0 1 1 1 0 Ring finger domain Zn-ribbon_8 PF09723.10 EAQ85163.1 - 0.088 12.9 0.1 0.22 11.7 0.1 1.6 1 0 0 1 1 1 0 Zinc ribbon domain Clr5 PF14420.6 EAQ85164.1 - 4.6e-17 62.0 2.5 6.6e-17 61.5 2.5 1.2 1 0 0 1 1 1 1 Clr5 domain MORN_2 PF07661.13 EAQ85165.1 - 0.15 12.4 0.0 0.35 11.2 0.0 1.7 1 0 0 1 1 1 0 MORN repeat variant SIL1 PF16782.5 EAQ85166.1 - 0.013 14.7 0.6 0.018 14.2 0.6 1.1 1 0 0 1 1 1 0 Nucleotide exchange factor SIL1 Apolipoprotein PF01442.18 EAQ85166.1 - 0.016 15.1 5.3 0.025 14.5 5.3 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain HMGL-like PF00682.19 EAQ85166.1 - 0.017 14.7 3.4 0.026 14.1 3.4 1.3 1 0 0 1 1 1 0 HMGL-like EIID-AGA PF03613.14 EAQ85166.1 - 0.023 13.9 0.1 0.035 13.3 0.1 1.2 1 0 0 1 1 1 0 PTS system mannose/fructose/sorbose family IID component PIN_2 PF10130.9 EAQ85166.1 - 1.4 9.1 3.4 1.2 9.4 0.8 2.0 1 1 1 2 2 2 0 PIN domain Arrestin_C PF02752.22 EAQ85167.1 - 5.1e-08 33.5 0.0 7.5e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain WD40 PF00400.32 EAQ85168.1 - 6.1e-11 42.7 18.4 0.00014 22.6 0.8 4.3 4 1 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAQ85168.1 - 3.7e-06 27.2 0.0 0.00037 20.7 0.0 2.6 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 EAQ85168.1 - 0.0083 16.0 0.0 5.2 7.1 0.0 3.1 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat eIF2A PF08662.11 EAQ85168.1 - 0.017 15.0 0.0 0.027 14.3 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.12 EAQ85168.1 - 0.093 10.7 0.0 0.13 10.2 0.0 1.1 1 0 0 1 1 1 0 IKI3 family EF_assoc_2 PF08356.12 EAQ85169.1 - 3.8e-33 113.3 0.0 8.1e-33 112.3 0.0 1.6 1 0 0 1 1 1 1 EF hand associated EF_assoc_1 PF08355.12 EAQ85169.1 - 1.7e-31 107.6 0.6 3.7e-31 106.5 0.6 1.6 1 0 0 1 1 1 1 EF hand associated Ras PF00071.22 EAQ85169.1 - 2.6e-25 88.9 0.0 7.4e-17 61.4 0.0 2.2 2 0 0 2 2 2 2 Ras family Roc PF08477.13 EAQ85169.1 - 4.4e-15 55.9 0.0 8.1e-10 39.0 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 EAQ85169.1 - 4.6e-08 33.1 0.0 0.00011 22.2 0.0 2.8 2 1 0 2 2 2 2 50S ribosome-binding GTPase EF-hand_1 PF00036.32 EAQ85169.1 - 6.3e-07 28.5 3.0 0.017 14.6 0.1 2.6 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EAQ85169.1 - 2.3e-06 27.9 0.1 0.0013 19.1 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain pair AAA_29 PF13555.6 EAQ85169.1 - 3.1e-06 26.8 0.1 0.0031 17.2 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.6 EAQ85169.1 - 3.3e-06 27.4 0.0 0.047 14.0 0.0 2.6 2 1 0 2 2 2 2 AAA domain Dynamin_N PF00350.23 EAQ85169.1 - 1.2e-05 25.5 0.2 0.087 12.9 0.1 2.7 2 1 1 3 3 3 2 Dynamin family AAA_16 PF13191.6 EAQ85169.1 - 1.5e-05 25.4 0.0 0.037 14.4 0.0 2.5 2 1 0 2 2 2 2 AAA ATPase domain EF-hand_6 PF13405.6 EAQ85169.1 - 7.5e-05 22.4 3.1 0.22 11.5 0.3 2.7 2 0 0 2 2 2 2 EF-hand domain RsgA_GTPase PF03193.16 EAQ85169.1 - 0.00017 21.5 0.1 1.6 8.6 0.1 3.2 2 1 0 3 3 3 2 RsgA GTPase ABC_tran PF00005.27 EAQ85169.1 - 0.00054 20.5 0.0 1.1 9.7 0.0 2.4 2 0 0 2 2 2 2 ABC transporter GTP_EFTU PF00009.27 EAQ85169.1 - 0.00076 19.1 0.0 3.6 7.1 0.0 3.2 2 1 0 3 3 3 1 Elongation factor Tu GTP binding domain DUF815 PF05673.13 EAQ85169.1 - 0.0012 18.1 0.0 0.86 8.7 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_24 PF13479.6 EAQ85169.1 - 0.0012 18.6 0.0 0.15 11.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 EAQ85169.1 - 0.0012 18.7 0.0 1.8 8.5 0.0 2.8 3 0 0 3 3 2 2 NACHT domain Ploopntkinase3 PF18751.1 EAQ85169.1 - 0.0015 18.5 0.0 0.79 9.6 0.0 2.3 2 0 0 2 2 2 1 P-loop Nucleotide Kinase3 RNA_helicase PF00910.22 EAQ85169.1 - 0.0031 17.9 0.0 0.72 10.3 0.0 2.5 2 0 0 2 2 2 1 RNA helicase EF-hand_5 PF13202.6 EAQ85169.1 - 0.0078 15.7 4.3 1.3 8.7 1.4 2.7 2 0 0 2 2 2 2 EF hand AAA_28 PF13521.6 EAQ85169.1 - 0.0085 16.4 0.0 3 8.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 EAQ85169.1 - 0.011 15.3 0.0 0.98 8.9 0.1 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_33 PF13671.6 EAQ85169.1 - 0.013 15.6 0.0 4.8 7.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 EAQ85169.1 - 0.02 14.3 0.0 0.9 8.9 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain EF-hand_10 PF14788.6 EAQ85169.1 - 0.034 14.0 0.8 0.36 10.7 0.1 2.4 2 0 0 2 2 2 0 EF hand AAA_15 PF13175.6 EAQ85169.1 - 0.045 13.5 0.0 4.1 7.0 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_18 PF13238.6 EAQ85169.1 - 0.049 14.2 0.0 1.3 9.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain SPARC_Ca_bdg PF10591.9 EAQ85169.1 - 0.057 13.7 0.0 8.7 6.7 0.0 3.0 2 1 1 3 3 2 0 Secreted protein acidic and rich in cysteine Ca binding region Septin PF00735.18 EAQ85169.1 - 0.065 12.5 0.0 0.43 9.8 0.0 2.0 2 0 0 2 2 2 0 Septin AAA PF00004.29 EAQ85169.1 - 0.071 13.5 0.0 3.4 8.1 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) IIGP PF05049.13 EAQ85169.1 - 0.08 12.0 0.1 2 7.4 0.0 2.3 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) Viral_helicase1 PF01443.18 EAQ85169.1 - 0.097 12.4 0.1 6.2 6.5 0.0 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_21 PF13304.6 EAQ85169.1 - 0.12 12.2 0.1 0.45 10.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 EAQ85169.1 - 0.12 11.9 0.1 13 5.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain AIG1 PF04548.16 EAQ85169.1 - 0.13 11.6 0.9 1 8.6 0.3 2.5 3 0 0 3 3 3 0 AIG1 family cobW PF02492.19 EAQ85169.1 - 0.13 11.8 1.3 14 5.2 0.0 3.7 3 1 1 4 4 4 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.6 EAQ85169.1 - 0.15 12.6 0.4 10 6.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain EF-hand_8 PF13833.6 EAQ85169.1 - 1 9.3 4.4 5.4 7.0 0.2 2.6 2 0 0 2 2 2 0 EF-hand domain pair Pox_MCEL PF03291.16 EAQ85170.1 - 2.8e-73 246.9 0.0 1.1e-51 175.9 0.0 2.1 2 0 0 2 2 2 2 mRNA capping enzyme Methyltransf_25 PF13649.6 EAQ85170.1 - 7.7e-11 42.6 0.3 1.3e-05 25.8 0.0 2.7 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_12 PF08242.12 EAQ85170.1 - 7.2e-10 39.5 0.1 0.0022 18.7 0.0 2.9 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_31 PF13847.6 EAQ85170.1 - 1.5e-06 28.1 0.0 7.8e-05 22.5 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EAQ85170.1 - 4.2e-06 27.3 0.3 0.067 13.9 0.0 2.7 3 0 0 3 3 3 2 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 EAQ85170.1 - 0.00019 20.7 0.0 0.00034 19.9 0.0 1.3 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family Raftlin PF15250.6 EAQ85170.1 - 0.00027 19.8 0.3 0.00027 19.8 0.3 1.5 2 0 0 2 2 2 1 Raftlin Methyltransf_23 PF13489.6 EAQ85170.1 - 0.0006 19.7 0.0 0.0013 18.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 EAQ85170.1 - 0.049 12.6 0.0 0.078 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) RPN7 PF10602.9 EAQ85171.1 - 4.7e-58 195.7 0.4 8.2e-58 194.9 0.4 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 EAQ85171.1 - 2.4e-13 50.5 0.0 5.8e-13 49.3 0.0 1.6 1 0 0 1 1 1 1 PCI domain MFS18 PF17352.2 EAQ85171.1 - 0.0011 19.4 0.4 0.002 18.5 0.4 1.4 1 0 0 1 1 1 1 Male Flower Specific protein 18 Aminotran_1_2 PF00155.21 EAQ85172.1 - 2e-36 126.0 0.0 2.3e-30 106.0 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class I and II HrpB7 PF09486.10 EAQ85174.1 - 0.0047 17.3 7.4 0.0047 17.3 7.4 5.5 2 2 1 5 5 5 1 Bacterial type III secretion protein (HrpB7) Fib_alpha PF08702.10 EAQ85174.1 - 0.013 15.7 4.1 0.013 15.7 4.1 6.3 1 1 6 7 7 7 0 Fibrinogen alpha/beta chain family MbeD_MobD PF04899.12 EAQ85174.1 - 0.44 10.7 24.5 0.23 11.6 1.3 6.1 5 1 1 6 6 6 0 MbeD/MobD like CD99L2 PF12301.8 EAQ85175.1 - 0.1 12.9 0.1 0.1 12.9 0.1 1.8 1 1 1 2 2 2 0 CD99 antigen like protein 2 NUC153 PF08159.12 EAQ85176.1 - 4.4e-12 45.6 0.7 4.4e-12 45.6 0.7 1.9 2 0 0 2 2 2 1 NUC153 domain WD40 PF00400.32 EAQ85176.1 - 4.1e-05 24.3 0.0 1.3 10.0 0.0 3.7 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAQ85176.1 - 0.0021 18.3 0.0 0.005 17.1 0.0 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain Spt5_N PF11942.8 EAQ85176.1 - 3.3 8.7 6.7 1.1 10.3 0.6 2.5 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Med13_C PF06333.12 EAQ85177.1 - 1.9e-89 300.2 2.0 1.9e-89 300.2 2.0 1.9 2 0 0 2 2 2 1 Mediator complex subunit 13 C-terminal domain Med13_N PF11597.8 EAQ85177.1 - 5e-19 68.8 0.0 2.4e-17 63.3 0.0 3.1 2 1 0 2 2 2 1 Mediator complex subunit 13 N-terminal MID_MedPIWI PF18296.1 EAQ85177.1 - 1.2e-12 48.2 3.9 1.2e-05 25.3 0.0 3.2 2 1 1 3 3 3 2 MID domain of medPIWI PNP_UDP_1 PF01048.20 EAQ85178.1 - 1.8e-42 145.2 0.8 2.1e-42 145.0 0.8 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily Atx10homo_assoc PF09759.9 EAQ85179.1 - 1.3e-10 41.2 0.0 3.2e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 Spinocerebellar ataxia type 10 protein domain KH_1 PF00013.29 EAQ85180.1 - 4.2e-101 330.8 31.1 1.3e-13 50.6 0.2 13.4 13 1 0 13 13 13 10 KH domain SLS PF14611.6 EAQ85180.1 - 4.9e-18 65.8 1.0 0.011 15.6 0.1 8.4 3 2 5 9 9 9 4 Mitochondrial inner-membrane-bound regulator KH_2 PF07650.17 EAQ85180.1 - 1.1e-12 47.6 25.7 0.011 15.6 0.3 8.5 8 1 0 9 9 9 5 KH domain BON PF04972.17 EAQ85180.1 - 0.025 14.9 1.1 1.8 8.9 0.1 3.8 3 0 0 3 3 3 0 BON domain PRONE PF03759.13 EAQ85180.1 - 0.036 12.9 0.0 0.07 11.9 0.0 1.4 1 0 0 1 1 1 0 PRONE (Plant-specific Rop nucleotide exchanger) KH_4 PF13083.6 EAQ85180.1 - 0.16 11.8 13.9 0.32 10.9 0.1 6.0 7 0 0 7 7 7 0 KH domain PHA_gran_rgn PF09650.10 EAQ85180.1 - 0.53 10.6 3.3 17 5.7 0.0 3.7 4 0 0 4 4 4 0 Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) KH_5 PF13184.6 EAQ85180.1 - 0.76 9.9 15.5 13 6.0 0.0 6.7 8 0 0 8 8 8 0 NusA-like KH domain DUF5300 PF17224.3 EAQ85180.1 - 2.2 8.6 13.3 12 6.2 0.1 5.3 6 0 0 6 6 6 0 Domain of unknown function (DUF5300) Pkinase PF00069.25 EAQ85181.1 - 1.4e-11 44.3 0.0 1.5e-11 44.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ85181.1 - 4.7e-07 29.4 0.0 5e-07 29.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase adh_short_C2 PF13561.6 EAQ85182.1 - 1.1e-61 208.4 0.4 1.6e-61 207.9 0.4 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EAQ85182.1 - 4.6e-50 169.8 0.4 6.5e-50 169.3 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EAQ85182.1 - 8.2e-10 38.9 0.3 1.3e-09 38.3 0.3 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EAQ85182.1 - 9.4e-05 22.0 0.1 0.00032 20.2 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EAQ85182.1 - 0.018 14.4 0.1 0.036 13.5 0.1 1.6 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EAQ85182.1 - 0.031 13.4 0.0 0.048 12.8 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 EAQ85182.1 - 0.083 11.9 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family ARID PF01388.21 EAQ85183.1 - 1.8e-18 67.0 0.4 9.1e-18 64.7 0.1 2.3 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain RFX_DNA_binding PF02257.15 EAQ85183.1 - 0.03 15.0 0.0 0.062 13.9 0.0 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain SEN1_N PF12726.7 EAQ85183.1 - 0.079 11.2 0.1 0.12 10.6 0.1 1.2 1 0 0 1 1 1 0 SEN1 N terminal SelR PF01641.18 EAQ85185.1 - 3.2e-39 133.7 0.0 3.9e-39 133.5 0.0 1.0 1 0 0 1 1 1 1 SelR domain zinc_ribbon_10 PF10058.9 EAQ85185.1 - 0.0017 18.1 0.1 0.64 9.8 0.0 2.2 2 0 0 2 2 2 2 Predicted integral membrane zinc-ribbon metal-binding protein TF_Zn_Ribbon PF08271.12 EAQ85185.1 - 0.033 13.7 0.9 3 7.4 0.3 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding DZR PF12773.7 EAQ85185.1 - 0.084 12.9 2.6 0.93 9.6 2.6 2.1 1 1 0 1 1 1 0 Double zinc ribbon Ribosomal_L37e PF01907.19 EAQ85185.1 - 0.25 11.5 4.0 1.1 9.5 0.8 2.3 2 0 0 2 2 2 0 Ribosomal protein L37e Chordopox_RPO7 PF05864.12 EAQ85185.1 - 0.3 11.3 1.0 22 5.4 0.1 2.3 2 0 0 2 2 2 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) zf-Mss51 PF13824.6 EAQ85185.1 - 0.67 10.1 3.0 6.7 6.9 0.5 2.9 2 1 1 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 ArfGap PF01412.18 EAQ85186.1 - 2.8e-10 40.3 5.5 7.8e-08 32.4 1.1 2.3 1 1 1 2 2 2 2 Putative GTPase activating protein for Arf Ysc84 PF04366.12 EAQ85188.1 - 1.2e-39 135.0 0.1 2.2e-39 134.1 0.1 1.4 1 0 0 1 1 1 1 Las17-binding protein actin regulator SH3_1 PF00018.28 EAQ85188.1 - 6.6e-14 51.2 0.2 1.7e-13 49.9 0.0 1.8 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 EAQ85188.1 - 9.5e-13 47.6 0.2 2.9e-12 46.1 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.6 EAQ85188.1 - 2e-12 46.8 1.3 3.9e-12 45.8 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain DUF3104 PF11302.8 EAQ85188.1 - 0.017 14.8 0.1 0.035 13.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3104) HSP70 PF00012.20 EAQ85192.1 - 4e-265 880.7 13.8 4.5e-265 880.5 13.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EAQ85192.1 - 1e-17 64.0 2.0 2.9e-16 59.2 0.4 2.2 2 0 0 2 2 2 2 MreB/Mbl protein HEPPP_synt_1 PF07307.11 EAQ85192.1 - 0.0095 15.6 0.4 0.019 14.6 0.4 1.4 1 0 0 1 1 1 1 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 FtsA PF14450.6 EAQ85192.1 - 0.011 16.1 6.3 6.7 7.2 0.4 3.6 3 1 0 3 3 3 0 Cell division protein FtsA Hydantoinase_A PF01968.18 EAQ85192.1 - 0.075 12.3 3.9 0.11 11.7 0.8 2.7 2 1 0 2 2 2 0 Hydantoinase/oxoprolinase SWI-SNF_Ssr4 PF08549.10 EAQ85192.1 - 1.6 7.3 7.2 0.21 10.2 0.4 2.0 2 0 0 2 2 2 0 Fungal domain of unknown function (DUF1750) GTP_EFTU PF00009.27 EAQ85193.1 - 3.2e-45 154.1 0.0 5.4e-45 153.3 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.10 EAQ85193.1 - 1.1e-25 89.7 1.3 2.3e-25 88.7 1.3 1.5 1 0 0 1 1 1 1 HBS1 N-terminus GTP_EFTU_D3 PF03143.17 EAQ85193.1 - 5e-09 36.4 0.0 2.6e-08 34.2 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EAQ85193.1 - 2.7e-07 30.9 0.0 6.9e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EAQ85193.1 - 8.1e-06 25.9 0.0 6.4e-05 23.0 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 EAQ85193.1 - 0.0023 17.4 0.1 0.27 10.7 0.1 2.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit DUF2213 PF09979.9 EAQ85193.1 - 0.011 15.7 0.0 0.023 14.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2213) Cpn60_TCP1 PF00118.24 EAQ85194.1 - 1.3e-156 522.1 7.3 1.5e-156 521.9 7.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family HECT PF00632.25 EAQ85195.1 - 3.8e-65 220.4 0.0 1.5e-64 218.5 0.0 1.8 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) AZUL PF16558.5 EAQ85195.1 - 1.5e-21 76.4 2.9 2.9e-21 75.4 2.9 1.5 1 0 0 1 1 1 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A zf-C2H2_2 PF12756.7 EAQ85196.1 - 7.4e-34 116.1 9.3 1e-27 96.4 2.0 3.4 3 0 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 EAQ85196.1 - 6.9e-09 35.8 19.1 8.6e-07 29.1 2.8 3.8 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EAQ85196.1 - 3e-08 33.8 6.5 4e-07 30.2 1.6 3.2 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 EAQ85196.1 - 0.00044 20.6 19.6 0.07 13.6 0.4 4.8 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EAQ85196.1 - 0.0017 19.0 15.4 1.7 9.7 0.3 5.5 5 1 0 5 5 5 2 C2H2-type zinc finger SnoaL_2 PF12680.7 EAQ85196.1 - 0.0067 17.1 0.2 0.17 12.5 0.2 2.4 2 0 0 2 2 2 1 SnoaL-like domain zf-DBF PF07535.12 EAQ85196.1 - 0.11 12.6 0.3 0.11 12.6 0.3 3.1 3 0 0 3 3 3 0 DBF zinc finger zf-3CxxC_2 PF17180.4 EAQ85196.1 - 0.38 11.5 6.1 2.7 8.8 0.2 3.4 3 0 0 3 3 3 0 Zinc-binding domain VHS PF00790.19 EAQ85197.1 - 6.7e-22 77.9 0.0 1.6e-21 76.6 0.0 1.7 2 0 0 2 2 2 1 VHS domain GAT PF03127.14 EAQ85197.1 - 0.00017 21.9 0.2 0.00044 20.5 0.2 1.6 1 0 0 1 1 1 1 GAT domain RWD PF05773.22 EAQ85198.1 - 0.00016 21.9 0.2 0.0022 18.2 0.0 2.3 2 0 0 2 2 2 1 RWD domain FUSC PF04632.12 EAQ85198.1 - 0.3 9.6 1.9 0.25 9.9 0.3 1.6 2 0 0 2 2 2 0 Fusaric acid resistance protein family OrfB_Zn_ribbon PF07282.11 EAQ85198.1 - 1.2 9.1 6.3 0.21 11.5 0.2 2.3 2 0 0 2 2 2 0 Putative transposase DNA-binding domain FYVE PF01363.21 EAQ85198.1 - 1.5 9.0 8.4 40 4.4 8.4 2.5 1 1 0 1 1 1 0 FYVE zinc finger HypA PF01155.19 EAQ85198.1 - 2.1 8.4 4.0 1.8 8.6 0.1 2.3 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_15 PF17032.5 EAQ85198.1 - 2.1 9.1 6.0 45 4.9 6.0 2.3 1 1 0 1 1 1 0 zinc-ribbon family zinc_ribbon_4 PF13717.6 EAQ85198.1 - 9.7 6.2 9.9 25 4.9 0.0 3.8 4 0 0 4 4 4 0 zinc-ribbon domain BING4CT PF08149.11 EAQ85200.1 - 0.0017 18.1 0.0 0.0029 17.4 0.0 1.4 1 0 0 1 1 1 1 BING4CT (NUC141) domain DUF3295 PF11702.8 EAQ85202.1 - 3.9e-120 402.5 37.4 1.4e-61 209.4 24.2 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF3295) DUF1752 PF08550.10 EAQ85202.1 - 1.1e-12 47.5 3.1 1.9e-12 46.8 3.1 1.4 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Fungal_trans_2 PF11951.8 EAQ85204.1 - 0.013 14.4 0.0 0.015 14.1 0.0 1.1 1 0 0 1 1 1 0 Fungal specific transcription factor domain TPMT PF05724.11 EAQ85204.1 - 0.022 14.4 0.0 0.092 12.4 0.0 1.9 2 0 0 2 2 2 0 Thiopurine S-methyltransferase (TPMT) AMP-binding PF00501.28 EAQ85205.1 - 8.5e-84 281.6 0.0 1.1e-83 281.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme UCH PF00443.29 EAQ85206.1 - 6.3e-36 124.2 0.0 8.9e-36 123.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EAQ85206.1 - 2e-09 37.5 0.0 1.8e-08 34.4 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.20 EAQ85206.1 - 9.6e-05 22.9 0.0 0.00022 21.7 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain USP8_dimer PF08969.11 EAQ85206.1 - 0.17 12.1 0.0 0.39 10.9 0.0 1.5 1 0 0 1 1 1 0 USP8 dimerisation domain VHS PF00790.19 EAQ85207.1 - 3.2e-39 134.0 0.0 7.3e-38 129.6 0.0 2.2 2 0 0 2 2 2 1 VHS domain UIM PF02809.20 EAQ85207.1 - 8e-07 28.6 12.4 0.0024 17.7 1.5 2.7 2 0 0 2 2 2 2 Ubiquitin interaction motif GAT PF03127.14 EAQ85207.1 - 2.8e-05 24.3 0.0 9.5e-05 22.6 0.0 2.0 1 0 0 1 1 1 1 GAT domain Npa1 PF11707.8 EAQ85207.1 - 0.062 12.7 0.1 0.12 11.7 0.1 1.4 1 0 0 1 1 1 0 Ribosome 60S biogenesis N-terminal DGF-1_C PF11040.8 EAQ85207.1 - 0.078 13.0 1.1 0.34 10.9 0.3 2.6 2 0 0 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus TerB_C PF15615.6 EAQ85207.1 - 5.9 7.2 8.8 0.38 11.0 2.5 2.1 2 0 0 2 2 2 0 TerB-C domain His_Phos_1 PF00300.22 EAQ85208.1 - 1.1e-13 51.3 0.7 2.3e-07 30.7 0.1 2.4 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) KCH PF16944.5 EAQ85209.1 - 2.3e-99 332.2 11.1 2.8e-99 332.0 11.1 1.1 1 0 0 1 1 1 1 Fungal potassium channel Cornifin PF02389.15 EAQ85209.1 - 3.1e-08 33.9 3.2 3.1e-08 33.9 3.2 1.9 1 1 0 1 1 1 1 Cornifin (SPRR) family Helitron_like_N PF14214.6 EAQ85210.1 - 9.7e-18 65.1 0.1 1.7e-17 64.3 0.1 1.3 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus UvrD_C_2 PF13538.6 EAQ85210.1 - 0.00034 20.4 0.0 0.00074 19.3 0.0 1.5 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.14 EAQ85210.1 - 0.0018 16.3 0.0 0.0026 15.8 0.0 1.1 1 0 0 1 1 1 1 Helicase PIF1 PF05970.14 EAQ85210.1 - 0.0019 17.5 0.0 0.003 16.8 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase zf-RING_7 PF02591.15 EAQ85210.1 - 0.098 12.9 0.2 25 5.2 0.0 2.8 2 0 0 2 2 2 0 C4-type zinc ribbon domain PIF1 PF05970.14 EAQ85211.1 - 9.4e-19 67.8 0.0 1.6e-18 67.0 0.0 1.3 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 EAQ85211.1 - 2.9e-07 30.4 0.0 1.4e-06 28.2 0.0 2.1 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.6 EAQ85211.1 - 0.0087 16.4 0.0 0.024 15.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 EAQ85211.1 - 0.027 14.3 0.0 0.077 12.8 0.0 1.8 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain PIF1 PF05970.14 EAQ85212.1 - 5.2e-16 58.8 0.0 9.1e-16 58.0 0.0 1.3 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 EAQ85212.1 - 0.00026 20.8 0.0 0.00082 19.1 0.0 1.9 2 1 0 2 2 2 1 AAA domain UvrD_C_2 PF13538.6 EAQ85212.1 - 0.05 13.4 0.0 0.15 11.9 0.0 1.9 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Ank_4 PF13637.6 EAQ85213.1 - 5.8e-54 179.8 18.1 1.2e-11 44.8 0.2 7.6 1 1 6 7 7 7 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAQ85213.1 - 1e-49 165.9 6.5 4.7e-11 42.7 0.0 5.7 2 1 4 6 6 6 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAQ85213.1 - 1.3e-46 157.1 8.7 1.3e-14 54.5 0.1 4.8 2 1 2 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.30 EAQ85213.1 - 1.8e-43 145.1 12.7 8.2e-06 26.0 0.0 8.2 8 0 0 8 8 8 7 Ankyrin repeat Ank_3 PF13606.6 EAQ85213.1 - 2.5e-34 113.4 5.0 0.00071 19.8 0.0 7.9 7 0 0 7 7 7 7 Ankyrin repeat PNP_UDP_1 PF01048.20 EAQ85213.1 - 1.4e-14 53.9 2.9 3e-13 49.6 0.3 3.5 2 2 1 3 3 3 1 Phosphorylase superfamily AAA_16 PF13191.6 EAQ85213.1 - 3.9e-05 24.1 0.0 0.00017 22.0 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 EAQ85213.1 - 0.00028 20.8 0.0 0.00077 19.4 0.0 1.8 1 0 0 1 1 1 1 NACHT domain Nse4-Nse3_bdg PF15412.6 EAQ85213.1 - 0.035 14.2 1.9 17 5.6 0.1 4.6 5 0 0 5 5 5 0 Binding domain of Nse4/EID3 to Nse3-MAGE AAA_22 PF13401.6 EAQ85213.1 - 0.099 12.9 0.0 0.62 10.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.14 EAQ85213.1 - 0.19 10.9 2.8 5.5 6.1 0.3 2.2 1 1 1 2 2 2 0 KAP family P-loop domain ABC_tran PF00005.27 EAQ85214.1 - 2.2e-46 157.8 0.1 3.3e-25 89.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 EAQ85214.1 - 3.4e-23 82.3 39.6 3.2e-15 56.1 18.2 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 EAQ85214.1 - 4.8e-22 79.1 2.2 1.5e-05 25.0 0.0 4.3 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EAQ85214.1 - 1.9e-08 33.9 2.8 0.0042 16.8 0.4 3.6 3 0 0 3 3 3 2 P-loop containing region of AAA domain SMC_N PF02463.19 EAQ85214.1 - 5.8e-07 29.2 3.2 0.18 11.2 0.0 4.0 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EAQ85214.1 - 0.0001 22.2 0.1 0.48 10.3 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 EAQ85214.1 - 0.00074 19.9 0.1 0.53 10.6 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain DUF4162 PF13732.6 EAQ85214.1 - 0.00091 19.9 0.0 0.13 13.0 0.0 2.7 3 0 0 3 3 2 1 Domain of unknown function (DUF4162) AAA_23 PF13476.6 EAQ85214.1 - 0.0019 18.7 6.9 0.22 12.0 0.6 2.4 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 EAQ85214.1 - 0.0052 16.5 3.7 1.2 8.8 0.1 2.7 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 EAQ85214.1 - 0.0054 16.5 0.0 4.1 7.0 0.1 3.0 3 0 0 3 3 3 1 AAA ATPase domain AAA_27 PF13514.6 EAQ85214.1 - 0.017 14.7 0.4 4.6 6.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EAQ85214.1 - 0.065 13.5 0.3 4.9 7.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 EAQ85214.1 - 0.13 12.2 0.0 12 5.7 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain SRP54 PF00448.22 EAQ85214.1 - 0.14 11.8 2.3 12 5.5 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain G-alpha PF00503.20 EAQ85214.1 - 0.28 10.3 0.1 1.4 8.0 0.0 1.9 2 0 0 2 2 2 0 G-protein alpha subunit MukB PF04310.12 EAQ85214.1 - 0.56 10.0 1.7 16 5.2 0.1 2.4 2 0 0 2 2 2 0 MukB N-terminal DUF87 PF01935.17 EAQ85214.1 - 2 8.5 4.2 17 5.4 0.1 2.2 2 0 0 2 2 2 0 Helicase HerA, central domain tRNA-synt_2 PF00152.20 EAQ85215.1 - 5.9e-73 245.7 0.3 7.6e-73 245.3 0.3 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EAQ85215.1 - 3.5e-12 46.1 0.1 9.7e-12 44.7 0.1 1.8 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EAQ85215.1 - 5.2e-08 32.7 0.0 0.00094 18.7 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) zf-Di19 PF05605.12 EAQ85216.1 - 0.025 14.8 0.1 0.087 13.1 0.1 1.9 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding bZIP_1 PF00170.21 EAQ85216.1 - 0.13 12.4 2.3 0.32 11.1 2.3 1.6 1 0 0 1 1 1 0 bZIP transcription factor zf-C2H2_4 PF13894.6 EAQ85216.1 - 0.17 12.8 2.3 0.34 11.9 0.5 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger DNA_pol_phi PF04931.13 EAQ85216.1 - 0.4 8.7 13.4 0.72 7.9 13.4 1.3 1 0 0 1 1 1 0 DNA polymerase phi zf-C2H2 PF00096.26 EAQ85216.1 - 1.1 9.9 3.2 0.64 10.6 0.4 2.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type DNA_pol_phi PF04931.13 EAQ85217.1 - 1.5 6.8 9.7 1.8 6.5 9.7 1.0 1 0 0 1 1 1 0 DNA polymerase phi Putative_PNPOx PF01243.20 EAQ85218.1 - 3.4e-07 30.3 0.0 0.0027 17.9 0.0 2.8 3 0 0 3 3 3 2 Pyridoxamine 5'-phosphate oxidase CTP_transf_like PF01467.26 EAQ85219.1 - 7.5e-13 48.9 0.0 1.1e-12 48.4 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase-like Ion_trans_2 PF07885.16 EAQ85221.1 - 2.1e-34 117.3 28.7 5.3e-21 74.4 3.4 3.6 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.31 EAQ85221.1 - 0.00033 20.0 20.9 0.00074 18.8 0.1 3.3 2 1 0 3 3 3 2 Ion transport protein SieB PF14163.6 EAQ85221.1 - 0.028 13.9 0.0 0.094 12.2 0.0 1.9 1 0 0 1 1 1 0 Super-infection exclusion protein B Ribosomal_L6 PF00347.23 EAQ85223.1 - 5.1e-15 55.9 0.0 1.3e-09 38.6 0.0 2.7 2 2 0 2 2 2 2 Ribosomal protein L6 Inositol_P PF00459.25 EAQ85224.1 - 9.2e-49 166.4 0.3 1.9e-48 165.4 0.3 1.4 1 1 0 1 1 1 1 Inositol monophosphatase family PALP PF00291.25 EAQ85225.1 - 0.031 13.7 0.1 1.1 8.7 0.0 2.0 1 1 1 2 2 2 0 Pyridoxal-phosphate dependent enzyme RVT_1 PF00078.27 EAQ85226.1 - 2.6e-27 95.8 0.0 1.3e-26 93.5 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Dimer_Tnp_hAT PF05699.14 EAQ85226.1 - 2.7e-07 30.3 0.1 6.3e-07 29.1 0.1 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region SlyX PF04102.12 EAQ85226.1 - 0.0084 16.7 5.7 0.097 13.3 5.7 2.8 1 1 0 1 1 1 1 SlyX USP8_interact PF08941.10 EAQ85226.1 - 0.053 13.3 0.6 0.23 11.3 0.1 2.3 2 0 0 2 2 2 0 USP8 interacting CENP-F_leu_zip PF10473.9 EAQ85226.1 - 0.088 12.8 0.8 0.28 11.2 0.8 1.9 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HMMR_N PF15905.5 EAQ85226.1 - 0.095 12.2 0.4 0.17 11.3 0.4 1.3 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal CorA PF01544.18 EAQ85226.1 - 0.096 12.0 1.5 0.19 11.0 1.5 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein PKcGMP_CC PF16808.5 EAQ85226.1 - 0.16 11.8 0.8 0.56 10.1 0.8 1.9 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Fib_alpha PF08702.10 EAQ85226.1 - 0.19 11.9 0.8 0.56 10.4 0.8 1.8 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF3584 PF12128.8 EAQ85226.1 - 0.77 7.2 5.6 1.2 6.6 5.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF2968 PF11180.8 EAQ85226.1 - 1 9.0 5.3 2.7 7.6 5.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) MLTR_LBD PF17765.1 EAQ85226.1 - 9.5 6.3 8.7 0.85 9.7 0.0 3.6 4 0 0 4 4 4 0 MmyB-like transcription regulator ligand binding domain HET PF06985.11 EAQ85227.1 - 7.9e-32 110.6 0.2 1.7e-31 109.6 0.0 1.7 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Lactonase PF10282.9 EAQ85228.1 - 8.5e-14 51.6 0.0 6.1e-13 48.7 0.0 1.9 1 1 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Dioxygenase_C PF00775.21 EAQ85229.1 - 3.4e-39 134.2 0.0 4.6e-39 133.7 0.0 1.1 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 EAQ85229.1 - 1.4e-05 24.8 0.0 2.7e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 EAQ85229.1 - 0.007 16.6 0.0 0.027 14.7 0.0 2.0 1 1 0 1 1 1 1 Carboxypeptidase regulatory-like domain SpaA PF17802.1 EAQ85229.1 - 0.066 13.6 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 Prealbumin-like fold domain Complex1_30kDa PF00329.19 EAQ85230.1 - 2.2e-41 141.3 0.1 3.4e-41 140.7 0.1 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit zf-RING_4 PF14570.6 EAQ85231.1 - 8e-20 70.4 11.9 1.6e-19 69.4 11.9 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_1 PF00076.22 EAQ85231.1 - 4.1e-09 36.1 0.0 1.3e-08 34.5 0.0 2.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Helicase_C PF00271.31 EAQ85231.1 - 1.6e-07 31.6 0.1 4.3e-07 30.2 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.6 EAQ85231.1 - 2.3e-06 27.4 10.7 2.3e-06 27.4 10.7 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.29 EAQ85231.1 - 3.9e-05 23.5 0.0 8.8e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EAQ85231.1 - 0.00011 22.2 0.0 0.00028 20.9 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Rtf2 PF04641.12 EAQ85231.1 - 0.00034 20.1 2.7 0.00034 20.1 2.7 4.2 5 0 0 5 5 4 1 Rtf2 RING-finger SET_assoc PF11767.8 EAQ85231.1 - 0.0083 15.7 0.0 0.019 14.6 0.0 1.5 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated zf-C3HC4 PF00097.25 EAQ85231.1 - 0.072 13.0 9.9 0.18 11.7 9.9 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Nup35_RRM_2 PF14605.6 EAQ85231.1 - 0.13 12.3 0.0 0.31 11.1 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Prok-RING_4 PF14447.6 EAQ85231.1 - 0.27 11.1 11.2 0.41 10.5 9.1 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Baculo_IE-1 PF05290.11 EAQ85231.1 - 0.48 10.4 7.0 0.94 9.4 7.0 1.4 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-UDP PF14569.6 EAQ85231.1 - 0.78 9.9 5.7 2 8.6 5.7 1.7 1 0 0 1 1 1 0 Zinc-binding RING-finger Ank_4 PF13637.6 EAQ85234.1 - 3.8e-15 56.0 0.0 1.4e-10 41.5 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EAQ85234.1 - 1.4e-14 53.8 0.5 0.0006 20.2 0.1 3.8 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.7 EAQ85234.1 - 1.9e-13 50.8 0.1 3.2e-11 43.6 0.1 3.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAQ85234.1 - 4.3e-10 39.0 0.5 0.048 14.2 0.1 4.1 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 EAQ85234.1 - 4.4e-10 39.6 0.3 0.0033 17.7 0.0 3.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) DUF4777 PF16007.5 EAQ85234.1 - 0.16 12.3 0.1 0.6 10.4 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4777) FAD_binding_4 PF01565.23 EAQ85235.1 - 2.5e-23 82.3 0.6 5.5e-23 81.2 0.6 1.6 1 1 0 1 1 1 1 FAD binding domain BBE PF08031.12 EAQ85235.1 - 4.6e-07 29.8 0.1 1.1e-06 28.6 0.1 1.7 1 0 0 1 1 1 1 Berberine and berberine like adh_short_C2 PF13561.6 EAQ85236.1 - 5.2e-50 170.2 0.5 6.8e-50 169.8 0.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EAQ85236.1 - 4.4e-44 150.3 0.0 6.1e-44 149.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EAQ85236.1 - 7.7e-07 29.2 0.1 1.2e-06 28.6 0.1 1.2 1 0 0 1 1 1 1 KR domain RVT_1 PF00078.27 EAQ85238.1 - 5.4e-23 81.7 0.0 9.6e-23 80.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-C3HC PF07967.13 EAQ85239.1 - 3.4e-33 114.5 0.1 5.2e-33 113.9 0.1 1.2 1 0 0 1 1 1 1 C3HC zinc finger-like BIR PF00653.21 EAQ85239.1 - 0.022 15.4 0.2 0.042 14.5 0.2 1.4 1 0 0 1 1 1 0 Inhibitor of Apoptosis domain ORC6 PF05460.13 EAQ85239.1 - 3 7.0 6.3 4.9 6.3 6.3 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) E1-E2_ATPase PF00122.20 EAQ85240.1 - 1.1e-47 161.9 2.4 1.2e-47 161.8 0.3 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 EAQ85240.1 - 1.1e-40 140.2 1.1 2.8e-40 138.8 0.2 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 EAQ85240.1 - 4.6e-37 126.3 0.6 3.2e-11 43.5 0.1 5.0 4 1 0 4 4 4 4 Heavy-metal-associated domain Hydrolase_3 PF08282.12 EAQ85240.1 - 7.6e-06 25.8 1.0 0.00042 20.1 0.4 2.8 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EAQ85240.1 - 2.7e-05 24.6 0.0 0.0001 22.8 0.0 2.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase AP_endonuc_2 PF01261.24 EAQ85240.1 - 0.13 11.7 0.0 0.6 9.5 0.0 2.1 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel DUF4231 PF14015.6 EAQ85240.1 - 0.25 11.8 1.4 13 6.3 0.2 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) FAD_binding_1 PF00667.20 EAQ85241.1 - 3.3e-41 141.3 0.0 6.2e-41 140.4 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain POR PF01558.18 EAQ85241.1 - 1.7e-10 41.3 0.0 4.2e-10 40.0 0.0 1.6 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase NAD_binding_1 PF00175.21 EAQ85241.1 - 3e-10 40.7 0.0 9e-10 39.2 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain PFOR_II PF17147.4 EAQ85241.1 - 5.6e-08 33.0 0.1 1.6e-07 31.6 0.1 1.8 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II Transketolase_C PF02780.20 EAQ85241.1 - 0.026 14.4 1.1 0.063 13.2 0.1 2.2 2 0 0 2 2 2 0 Transketolase, C-terminal domain DUF4124 PF13511.6 EAQ85241.1 - 0.041 14.2 0.5 0.24 11.7 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4124) Fe-ADH PF00465.19 EAQ85242.1 - 1.2e-101 340.2 0.0 1.5e-101 339.9 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 EAQ85242.1 - 4.4e-14 52.8 0.0 2.9e-10 40.3 0.0 2.4 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Peripla_BP_6 PF13458.6 EAQ85242.1 - 0.025 14.2 0.0 0.04 13.6 0.0 1.4 1 0 0 1 1 1 0 Periplasmic binding protein Sec3_C PF09763.9 EAQ85244.1 - 1.4e-262 873.2 0.0 1.7e-262 872.9 0.0 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.6 EAQ85244.1 - 4.4e-28 97.2 0.0 8e-28 96.4 0.0 1.4 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Sec3_C_2 PF15278.6 EAQ85244.1 - 0.0038 17.5 0.7 0.015 15.7 0.0 2.4 2 0 0 2 2 2 1 Sec3 exocyst complex subunit Ntox10 PF15520.6 EAQ85244.1 - 0.022 14.6 0.6 0.1 12.5 0.1 2.0 2 0 0 2 2 2 0 Novel toxin 10 DUF2018 PF09442.10 EAQ85244.1 - 0.18 12.8 1.6 0.55 11.2 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF2018) Vps52 PF04129.12 EAQ85244.1 - 0.59 8.8 4.6 0.33 9.7 0.3 2.2 2 0 0 2 2 2 0 Vps52 / Sac2 family HECT PF00632.25 EAQ85246.1 - 6.9e-76 255.7 0.0 5.2e-75 252.8 0.0 2.0 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) BUD22 PF09073.10 EAQ85246.1 - 0.0006 19.3 18.7 0.0006 19.3 18.7 3.8 3 1 0 4 4 4 1 BUD22 HEAT PF02985.22 EAQ85246.1 - 0.034 14.4 0.1 38 4.9 0.0 4.2 3 0 0 3 3 3 0 HEAT repeat PI3K_1B_p101 PF10486.9 EAQ85246.1 - 2.1 6.0 7.6 3.4 5.3 7.6 1.3 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit E1_dh PF00676.20 EAQ85247.1 - 1.2e-87 293.7 0.0 1.4e-87 293.4 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 EAQ85247.1 - 0.00038 20.3 0.0 0.0063 16.3 0.0 2.4 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.6 EAQ85247.1 - 0.082 12.1 0.0 0.57 9.3 0.0 2.1 2 0 0 2 2 2 0 1-deoxy-D-xylulose-5-phosphate synthase XFP_N PF09364.10 EAQ85247.1 - 0.15 10.8 0.0 0.33 9.7 0.0 1.5 1 0 0 1 1 1 0 XFP N-terminal domain Ubie_methyltran PF01209.18 EAQ85248.1 - 2.5e-70 236.4 0.0 2.9e-42 144.6 0.0 2.1 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 EAQ85248.1 - 1.5e-12 48.0 0.0 4.7e-06 27.2 0.0 2.8 2 1 0 3 3 3 2 Methyltransferase domain Methyltransf_11 PF08241.12 EAQ85248.1 - 4.1e-10 40.2 0.0 1.1e-05 26.0 0.0 2.9 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_12 PF08242.12 EAQ85248.1 - 3.1e-09 37.4 0.0 6.5e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAQ85248.1 - 4.3e-08 33.1 0.0 2.5e-07 30.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EAQ85248.1 - 1.1e-05 25.4 0.0 1.6e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 EAQ85248.1 - 0.025 14.6 0.0 0.051 13.6 0.0 1.5 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_8 PF05148.15 EAQ85248.1 - 0.15 11.9 0.0 0.35 10.7 0.0 1.5 1 0 0 1 1 1 0 Hypothetical methyltransferase DUF2433 PF10360.9 EAQ85249.1 - 2e-49 166.8 0.0 3.2e-49 166.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) Metallophos PF00149.28 EAQ85249.1 - 0.0011 19.5 0.0 0.0022 18.5 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EAQ85249.1 - 0.0053 17.0 0.0 0.02 15.1 0.0 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain CCDC53 PF10152.9 EAQ85249.1 - 0.03 14.8 0.5 0.078 13.4 0.5 1.7 1 1 0 1 1 1 0 Subunit CCDC53 of WASH complex Glyoxalase PF00903.25 EAQ85250.1 - 1.3e-10 41.6 0.3 2.6e-10 40.6 0.3 1.5 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 EAQ85250.1 - 2.2e-06 27.6 0.1 4.2e-06 26.7 0.1 1.5 1 1 0 1 1 1 1 Glyoxalase-like domain SBP_bac_11 PF13531.6 EAQ85251.1 - 0.012 15.4 0.3 0.31 10.7 0.0 2.2 1 1 0 2 2 2 0 Bacterial extracellular solute-binding protein E3_binding PF02817.17 EAQ85251.1 - 0.084 13.2 0.0 0.21 12.0 0.0 1.7 1 0 0 1 1 1 0 e3 binding domain Glyco_hydro_61 PF03443.14 EAQ85252.1 - 1.1e-19 71.2 0.0 2.5e-15 57.0 0.1 3.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 61 UFC1 PF08694.11 EAQ85252.1 - 0.046 13.4 0.1 0.066 12.9 0.1 1.3 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 Fungal_trans_2 PF11951.8 EAQ85253.1 - 1.5e-10 40.5 0.0 2.1e-10 40.0 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EAQ85253.1 - 0.017 15.2 8.6 0.032 14.4 8.6 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3079 PF11278.8 EAQ85253.1 - 0.49 10.3 5.9 1.5 8.7 5.9 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3079) RTA1 PF04479.13 EAQ85254.1 - 1.5e-20 73.7 7.5 1.2e-19 70.8 6.2 2.3 1 1 1 2 2 2 2 RTA1 like protein zf-NOSIP PF15906.5 EAQ85255.1 - 0.19 11.9 0.0 0.39 10.9 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein Zds_C PF08632.10 EAQ85257.1 - 4.7e-30 103.1 0.7 8.1e-30 102.3 0.7 1.4 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term Amidase PF01425.21 EAQ85258.1 - 3.9e-76 256.8 0.0 1.5e-75 254.9 0.0 1.7 1 1 0 1 1 1 1 Amidase CUE PF02845.16 EAQ85259.1 - 2.7e-05 23.8 0.0 7.1e-05 22.4 0.0 1.7 1 0 0 1 1 1 1 CUE domain Smr PF01713.21 EAQ85259.1 - 0.00035 20.9 0.1 0.0021 18.4 0.1 2.2 2 0 0 2 2 2 1 Smr domain UBA_4 PF14555.6 EAQ85259.1 - 0.13 12.1 0.0 0.85 9.5 0.0 2.3 2 0 0 2 2 2 0 UBA-like domain NPC1_N PF16414.5 EAQ85260.1 - 2.2e-83 279.6 10.3 3.2e-83 279.0 10.3 1.3 1 0 0 1 1 1 1 Niemann-Pick C1 N terminus Patched PF02460.18 EAQ85260.1 - 4e-74 250.2 15.1 4e-74 250.2 15.1 2.4 2 1 0 2 2 2 1 Patched family Sterol-sensing PF12349.8 EAQ85260.1 - 6.6e-50 168.9 8.7 6.6e-50 168.9 8.7 2.7 2 1 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.15 EAQ85260.1 - 3.9e-05 22.8 35.0 0.009 15.0 10.6 2.6 2 0 0 2 2 2 2 MMPL family Folate_rec PF03024.14 EAQ85260.1 - 6.3e-05 22.9 1.5 6.3e-05 22.9 1.5 1.7 2 0 0 2 2 2 1 Folate receptor family ACR_tran PF00873.19 EAQ85260.1 - 0.26 8.9 21.1 0.0071 14.1 12.5 2.0 2 0 0 2 2 2 0 AcrB/AcrD/AcrF family p450 PF00067.22 EAQ85262.1 - 5.1e-44 150.8 0.0 7.6e-44 150.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 FAM176 PF14851.6 EAQ85263.1 - 0.053 13.2 0.4 0.062 13.0 0.4 1.1 1 0 0 1 1 1 0 FAM176 family RNA_capsid PF03035.14 EAQ85263.1 - 0.062 13.3 0.6 0.072 13.1 0.6 1.1 1 0 0 1 1 1 0 Calicivirus putative RNA polymerase/capsid protein SpoIIIAH PF12685.7 EAQ85263.1 - 0.27 11.0 6.6 0.32 10.8 6.6 1.0 1 0 0 1 1 1 0 SpoIIIAH-like protein Mt_ATP-synt_B PF05405.14 EAQ85263.1 - 0.45 10.1 2.8 0.53 9.9 2.8 1.1 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Lipase_GDSL_2 PF13472.6 EAQ85265.1 - 1.5e-14 54.8 0.3 2.4e-14 54.2 0.3 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family CBM_1 PF00734.18 EAQ85265.1 - 2.8e-10 40.0 10.9 7.2e-10 38.7 10.9 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain Lipase_GDSL PF00657.22 EAQ85265.1 - 1.2e-08 35.2 0.1 8.4e-08 32.4 0.1 2.1 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 EAQ85265.1 - 0.055 13.6 0.0 0.089 12.9 0.0 1.3 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Pkinase PF00069.25 EAQ85267.1 - 1.2e-07 31.4 0.0 2e-05 24.1 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain CN_hydrolase PF00795.22 EAQ85267.1 - 2.2e-06 27.2 0.7 1.5e-05 24.5 0.1 2.0 1 1 1 2 2 2 1 Carbon-nitrogen hydrolase Aha1_N PF09229.11 EAQ85268.1 - 1.4e-29 103.1 0.3 2.3e-29 102.3 0.3 1.4 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 EAQ85268.1 - 6.9e-21 74.8 0.4 1.2e-20 74.0 0.4 1.4 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Complex1_LYR_2 PF13233.6 EAQ85270.1 - 2.5e-24 85.8 0.5 3.7e-24 85.3 0.1 1.4 2 0 0 2 2 2 1 Complex1_LYR-like Complex1_LYR PF05347.15 EAQ85270.1 - 0.0047 16.9 0.0 0.0072 16.4 0.0 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) MMR_HSR1 PF01926.23 EAQ85271.1 - 2.8e-16 59.6 0.0 6.7e-16 58.4 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EAQ85271.1 - 6.8e-09 35.5 0.0 1.8e-08 34.2 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 EAQ85271.1 - 9e-07 28.5 0.0 0.00084 18.9 0.0 2.1 2 0 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EAQ85271.1 - 9.2e-06 25.7 0.1 0.00089 19.2 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 EAQ85271.1 - 4.6e-05 23.5 0.0 0.00015 21.9 0.0 1.8 1 1 0 1 1 1 1 Dynamin family IIGP PF05049.13 EAQ85271.1 - 0.00017 20.8 0.0 0.072 12.1 0.0 2.0 2 0 0 2 2 2 2 Interferon-inducible GTPase (IIGP) AAA_29 PF13555.6 EAQ85271.1 - 0.0041 16.8 0.0 0.0082 15.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 EAQ85271.1 - 0.01 16.4 0.1 0.049 14.1 0.0 2.0 2 0 0 2 2 2 1 ABC transporter TniB PF05621.11 EAQ85271.1 - 0.016 14.6 0.0 0.046 13.1 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein Septin PF00735.18 EAQ85271.1 - 0.019 14.2 0.1 0.15 11.4 0.0 2.3 2 1 0 2 2 2 0 Septin AAA_28 PF13521.6 EAQ85271.1 - 0.02 15.2 2.3 0.28 11.4 0.3 2.2 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 EAQ85271.1 - 0.024 14.9 0.1 0.08 13.2 0.0 1.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_21 PF13304.6 EAQ85271.1 - 0.041 13.7 0.1 0.099 12.4 0.1 1.6 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 EAQ85271.1 - 0.045 14.0 0.1 0.18 12.1 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EAQ85271.1 - 0.047 14.1 1.3 0.12 12.8 1.3 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_15 PF13175.6 EAQ85271.1 - 0.22 11.2 0.1 0.32 10.7 0.1 1.1 1 0 0 1 1 1 0 AAA ATPase domain DHHC PF01529.20 EAQ85272.1 - 9.8e-26 90.5 3.9 9.8e-26 90.5 3.9 2.0 3 0 0 3 3 3 1 DHHC palmitoyltransferase BRCT_2 PF16589.5 EAQ85273.1 - 5.6e-13 49.1 0.0 1e-12 48.2 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Myb_DNA-bind_2 PF08914.11 EAQ85273.1 - 2.2e-09 37.4 1.2 2e-05 24.7 0.0 2.8 2 0 0 2 2 2 2 Rap1 Myb domain ARID PF01388.21 EAQ85273.1 - 0.00068 20.3 0.0 0.0013 19.4 0.0 1.5 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain Nop25 PF09805.9 EAQ85273.1 - 5.6 7.4 8.4 0.68 10.4 3.7 1.8 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) Peptidase_S64 PF08192.11 EAQ85274.1 - 0.014 14.0 0.0 0.016 13.7 0.0 1.1 1 0 0 1 1 1 0 Peptidase family S64 2OG-FeII_Oxy_2 PF13532.6 EAQ85276.1 - 2.1e-25 90.1 0.0 2.7e-25 89.7 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Pkinase PF00069.25 EAQ85277.1 - 9.7e-70 234.9 0.0 1.3e-69 234.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ85277.1 - 2e-29 102.7 0.0 2.5e-29 102.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EAQ85277.1 - 0.0012 17.9 0.0 0.014 14.4 0.0 2.0 2 0 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 EAQ85277.1 - 0.0023 17.3 0.0 0.0039 16.6 0.0 1.4 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 EAQ85277.1 - 0.01 15.8 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EAQ85277.1 - 0.02 14.0 0.0 0.03 13.4 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 EAQ85277.1 - 0.093 12.1 0.1 0.26 10.6 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Cyclin_N PF00134.23 EAQ85279.1 - 1.5e-13 50.6 0.1 2.5e-13 49.9 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 EAQ85279.1 - 7.3e-08 32.9 0.0 2.1e-07 31.4 0.0 1.8 1 0 0 1 1 1 1 Cyclin Glycos_transf_2 PF00535.26 EAQ85279.1 - 0.095 12.5 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 2 adh_short PF00106.25 EAQ85280.1 - 4.3e-23 81.8 0.0 2.3e-18 66.4 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EAQ85280.1 - 7.6e-15 55.1 0.1 1.7e-11 44.2 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EAQ85280.1 - 2.9e-07 30.6 0.1 5e-07 29.8 0.1 1.3 1 0 0 1 1 1 1 KR domain Zn_clus PF00172.18 EAQ85281.1 - 1.5e-08 34.7 6.2 3e-08 33.6 6.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EAQ85281.1 - 0.00062 18.7 0.6 0.001 18.0 0.4 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain RTA1 PF04479.13 EAQ85282.1 - 2.4e-51 174.3 8.4 3.1e-51 173.9 8.4 1.1 1 0 0 1 1 1 1 RTA1 like protein Glyoxalase PF00903.25 EAQ85284.1 - 7.1e-08 32.7 0.0 9.5e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily SnoaL_4 PF13577.6 EAQ85284.1 - 0.17 12.0 0.0 0.27 11.4 0.0 1.3 1 0 0 1 1 1 0 SnoaL-like domain BLM10_mid PF16507.5 EAQ85285.1 - 2e-200 666.9 0.0 3.8e-200 666.0 0.0 1.5 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 EAQ85285.1 - 7.1e-20 70.7 0.0 6.4e-19 67.7 0.0 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3437) BLM10_N PF16547.5 EAQ85285.1 - 5.7e-05 23.3 0.0 0.00025 21.3 0.0 2.2 2 0 0 2 2 2 1 Proteasome-substrate-size regulator, N-terminal HEAT PF02985.22 EAQ85285.1 - 2.7 8.5 5.7 22 5.6 0.1 4.8 6 0 0 6 6 6 0 HEAT repeat PIF1 PF05970.14 EAQ85287.1 - 1.2e-05 24.7 0.0 1.9e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase UvrD_C_2 PF13538.6 EAQ85287.1 - 0.013 15.3 0.0 0.045 13.6 0.0 1.9 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain Pkinase PF00069.25 EAQ85289.1 - 7.2e-32 110.8 0.0 8e-30 104.1 0.0 2.5 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ85289.1 - 1.1e-25 90.4 0.0 1.7e-25 89.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Fmp27_WPPW PF10359.9 EAQ85289.1 - 0.098 11.5 0.8 0.15 10.9 0.8 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Golgin_A5 PF09787.9 EAQ85289.1 - 0.58 9.6 9.4 0.95 8.9 9.4 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 GBP_C PF02841.14 EAQ85289.1 - 1.2 8.4 9.6 1.8 7.9 9.6 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain CheR_N PF03705.15 EAQ85290.1 - 0.037 13.8 0.1 0.085 12.6 0.1 1.6 1 0 0 1 1 1 0 CheR methyltransferase, all-alpha domain Complex1_LYR PF05347.15 EAQ85291.1 - 7.1e-09 35.6 0.0 1.7e-08 34.4 0.0 1.7 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 EAQ85291.1 - 0.0003 21.5 0.0 0.00095 19.9 0.0 1.9 1 0 0 1 1 1 1 Complex1_LYR-like UQ_con PF00179.26 EAQ85292.1 - 1e-12 47.9 0.0 1.3e-12 47.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EAQ85292.1 - 0.002 18.4 0.0 0.002 18.4 0.0 1.2 1 0 0 1 1 1 1 RWD domain Sec7_N PF12783.7 EAQ85293.1 - 5e-40 137.0 0.7 2.7e-39 134.6 0.0 2.5 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DCB PF16213.5 EAQ85293.1 - 2.3e-24 86.0 0.4 9.9e-23 80.7 0.5 2.6 2 0 0 2 2 2 1 Dimerisation and cyclophilin-binding domain of Mon2 Mon2_C PF16206.5 EAQ85293.1 - 1.9e-11 42.9 0.8 0.00075 17.8 0.0 4.0 4 0 0 4 4 4 3 C-terminal region of Mon2 protein DUF1981 PF09324.10 EAQ85293.1 - 0.00049 19.9 0.5 0.051 13.4 0.0 3.4 3 0 0 3 3 3 1 Domain of unknown function (DUF1981) Band_7 PF01145.25 EAQ85294.1 - 8.4e-31 107.3 1.3 1.4e-30 106.6 1.3 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Pox_A11 PF05061.13 EAQ85294.1 - 0.046 13.0 0.3 0.063 12.5 0.3 1.2 1 0 0 1 1 1 0 Poxvirus A11 Protein Band_7_1 PF13421.6 EAQ85294.1 - 0.12 12.1 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 SPFH domain-Band 7 family RNase_H PF00075.24 EAQ85295.1 - 3.5e-21 75.9 0.0 6.3e-21 75.1 0.0 1.4 1 0 0 1 1 1 1 RNase H TetR_C_12 PF16914.5 EAQ85295.1 - 0.0068 16.5 0.4 0.018 15.2 0.4 1.7 1 0 0 1 1 1 1 Bacterial transcriptional repressor C-terminal RVT_3 PF13456.6 EAQ85295.1 - 0.023 14.5 0.1 0.4 10.5 0.1 2.3 1 1 0 1 1 1 0 Reverse transcriptase-like p450 PF00067.22 EAQ85296.1 - 3e-52 177.9 0.0 4e-52 177.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Metallophos_2 PF12850.7 EAQ85297.1 - 2.1e-07 31.3 2.5 1.3e-05 25.5 2.5 3.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 EAQ85297.1 - 0.0005 20.6 0.7 0.0025 18.3 0.7 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Transp_inhibit PF18791.1 EAQ85297.1 - 0.13 11.8 0.3 0.47 10.0 0.1 1.9 2 0 0 2 2 2 0 Transport inhibitor response 1 protein domain MACPF PF01823.19 EAQ85299.1 - 1.2e-08 35.3 1.5 2e-08 34.6 0.6 1.7 1 1 1 2 2 2 1 MAC/Perforin domain Fil_haemagg_2 PF13332.6 EAQ85299.1 - 2.7 8.1 15.5 3.2 7.9 6.4 2.4 2 0 0 2 2 2 0 Hemagglutinin repeat SAP PF02037.27 EAQ85301.1 - 0.09 12.6 1.5 0.47 10.3 0.1 2.6 2 0 0 2 2 2 0 SAP domain TIP41 PF04176.13 EAQ85302.1 - 0.026 14.0 0.3 0.038 13.5 0.3 1.2 1 0 0 1 1 1 0 TIP41-like family Rab_bind PF16704.5 EAQ85302.1 - 0.12 12.4 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Rab binding domain UvrD_C_2 PF13538.6 EAQ85303.1 - 0.0032 17.3 0.0 0.0072 16.1 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain p450 PF00067.22 EAQ85304.1 - 2.4e-11 43.1 0.0 2.9e-11 42.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 EpuA PF11772.8 EAQ85304.1 - 0.014 15.1 0.2 6.6 6.5 0.0 2.6 2 1 0 2 2 2 0 DNA-directed RNA polymerase subunit beta Lactamase_B_2 PF12706.7 EAQ85305.1 - 1.2e-09 38.0 0.0 1.4e-09 37.7 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EAQ85305.1 - 0.0019 18.1 0.0 0.0019 18.1 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EAQ85305.1 - 0.011 15.8 0.5 0.017 15.2 0.5 1.2 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily DUF2235 PF09994.9 EAQ85306.1 - 1e-51 176.0 0.0 5.6e-33 114.5 0.0 2.1 1 1 1 2 2 2 2 Uncharacterized alpha/beta hydrolase domain (DUF2235) Pkinase PF00069.25 EAQ85307.1 - 3.5e-19 69.2 0.0 2.6e-18 66.4 0.0 2.4 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ85307.1 - 1.5e-10 40.8 0.0 4.9e-10 39.1 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 EAQ85307.1 - 0.12 11.3 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Seadorna_VP7 PF07387.11 EAQ85307.1 - 0.15 11.1 0.0 0.25 10.4 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 COX16 PF14138.6 EAQ85307.1 - 0.23 12.0 1.6 0.62 10.6 1.6 1.8 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein COX16 Pkinase PF00069.25 EAQ85308.1 - 2.8e-20 72.8 0.0 4.2e-20 72.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ85308.1 - 3.2e-09 36.5 0.0 5.3e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ifi-6-16 PF06140.13 EAQ85310.1 - 0.013 15.4 15.5 0.013 15.4 15.5 5.1 2 2 2 4 4 4 0 Interferon-induced 6-16 family RNA_pol_Rpb1_2 PF00623.20 EAQ85312.1 - 0.042 14.1 0.1 0.094 12.9 0.1 1.5 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 2 SlyX PF04102.12 EAQ85312.1 - 0.13 12.9 5.7 0.17 12.5 1.7 3.2 3 1 1 4 4 4 0 SlyX DUF4551 PF15087.6 EAQ85313.1 - 0.35 9.7 1.5 0.41 9.4 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) IATP PF04568.12 EAQ85314.1 - 3 8.3 5.7 4.7 7.7 1.7 2.2 2 0 0 2 2 2 0 Mitochondrial ATPase inhibitor, IATP Asparaginase_2 PF01112.18 EAQ85315.1 - 9.4e-56 189.1 4.0 1.3e-25 90.0 0.7 3.2 3 0 0 3 3 3 3 Asparaginase Dicistro_VP4 PF11492.8 EAQ85315.1 - 0.035 14.1 1.0 0.06 13.3 0.2 1.7 2 0 0 2 2 2 0 Cricket paralysis virus, VP4 Tim17 PF02466.19 EAQ85316.1 - 4.9e-26 91.3 8.4 6.6e-26 90.9 8.4 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Peptidase_M20 PF01546.28 EAQ85317.1 - 1.4e-22 80.4 0.0 5.5e-22 78.5 0.0 2.1 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 WD40 PF00400.32 EAQ85317.1 - 4.2e-15 55.9 5.2 0.0017 19.2 0.1 6.9 6 0 0 6 6 6 3 WD domain, G-beta repeat M20_dimer PF07687.14 EAQ85317.1 - 2e-06 27.7 0.0 3.9e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain ANAPC4_WD40 PF12894.7 EAQ85317.1 - 0.00077 19.7 0.1 12 6.2 0.0 4.8 5 1 0 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Peptidase_M28 PF04389.17 EAQ85317.1 - 0.00083 19.1 0.0 0.0017 18.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Ge1_WD40 PF16529.5 EAQ85317.1 - 0.0029 16.6 0.1 0.023 13.6 0.0 2.2 2 0 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein CNH PF00780.22 EAQ85317.1 - 0.018 14.7 0.0 0.042 13.5 0.0 1.5 2 0 0 2 2 2 0 CNH domain Mcl1_mid PF12341.8 EAQ85317.1 - 0.19 11.0 0.0 0.49 9.7 0.0 1.6 1 0 0 1 1 1 0 Minichromosome loss protein, Mcl1, middle region Chitin_bind_1 PF00187.19 EAQ85318.1 - 0.18 12.3 19.8 0.34 11.4 19.8 1.5 1 0 0 1 1 1 0 Chitin recognition protein DUF5326 PF17260.2 EAQ85319.1 - 0.11 12.7 0.6 0.2 11.8 0.6 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5326) Trypsin_2 PF13365.6 EAQ85320.1 - 0.029 15.3 2.9 0.11 13.4 0.5 2.7 2 1 0 2 2 2 0 Trypsin-like peptidase domain TauD PF02668.16 EAQ85321.1 - 7.4e-42 144.0 0.9 1.1e-41 143.5 0.9 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family NACHT PF05729.12 EAQ85322.1 - 0.051 13.5 0.3 1.5 8.7 0.0 3.0 3 0 0 3 3 3 0 NACHT domain RVT_1 PF00078.27 EAQ85323.1 - 1.6e-35 122.7 0.0 2.4e-35 122.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 EAQ85323.1 - 5e-08 32.8 0.0 1.6e-07 31.2 0.0 1.9 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase zf-RVT PF13966.6 EAQ85323.1 - 0.018 15.8 1.5 0.065 13.9 0.2 2.6 2 0 0 2 2 2 0 zinc-binding in reverse transcriptase Glyco_hydro_18 PF00704.28 EAQ85325.1 - 2e-43 149.3 0.0 2.9e-43 148.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.20 EAQ85325.1 - 5.4e-06 26.4 0.0 0.094 12.8 0.0 3.6 3 0 0 3 3 3 2 LysM domain Chitin_bind_1 PF00187.19 EAQ85325.1 - 0.00039 20.8 9.0 0.00039 20.8 9.0 3.4 3 0 0 3 3 3 1 Chitin recognition protein Carb_anhydrase PF00194.21 EAQ85326.1 - 2.2e-25 89.7 0.0 4.7e-25 88.6 0.0 1.5 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Med3 PF11593.8 EAQ85327.1 - 0.064 12.4 1.2 0.073 12.2 1.2 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal p450 PF00067.22 EAQ85330.1 - 4.6e-46 157.5 0.0 1.2e-33 116.6 0.0 2.1 1 1 1 2 2 2 2 Cytochrome P450 CorA PF01544.18 EAQ85331.1 - 0.00016 21.1 0.1 0.00025 20.5 0.1 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein TPR_12 PF13424.6 EAQ85334.1 - 4.8e-18 65.2 11.3 1.1e-10 41.6 1.0 6.3 5 2 1 6 6 6 3 Tetratricopeptide repeat TPR_10 PF13374.6 EAQ85334.1 - 1.8e-07 30.8 4.3 0.13 12.2 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 EAQ85334.1 - 3.7e-07 30.6 2.3 0.00024 21.6 0.0 4.0 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_MalT PF17874.1 EAQ85334.1 - 2.1e-06 27.4 0.2 0.0017 17.8 0.5 2.8 1 1 1 2 2 2 2 MalT-like TPR region TPR_1 PF00515.28 EAQ85334.1 - 3.5e-05 23.4 7.7 0.16 11.8 0.2 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 EAQ85334.1 - 0.0002 21.2 12.9 0.03 14.4 0.8 5.6 6 0 0 6 6 6 2 Tetratricopeptide repeat AAA_22 PF13401.6 EAQ85334.1 - 0.00026 21.3 0.0 0.0025 18.1 0.0 2.6 2 1 1 3 3 3 1 AAA domain TPR_8 PF13181.6 EAQ85334.1 - 0.00067 19.7 6.2 3.1 8.3 0.1 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat NB-ARC PF00931.22 EAQ85334.1 - 0.0017 17.6 0.0 0.0036 16.5 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 EAQ85334.1 - 0.0089 16.4 0.1 0.07 13.5 0.1 2.3 1 1 0 1 1 1 1 AAA ATPase domain DUF2225 PF09986.9 EAQ85334.1 - 0.022 14.5 0.7 0.054 13.2 0.3 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_14 PF13428.6 EAQ85334.1 - 0.047 14.5 2.0 7.1 7.7 0.2 4.3 5 0 0 5 5 3 0 Tetratricopeptide repeat IstB_IS21 PF01695.17 EAQ85334.1 - 0.077 12.7 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein MIT PF04212.18 EAQ85334.1 - 0.22 11.6 1.9 24 5.1 0.2 3.5 2 1 1 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_11 PF13414.6 EAQ85334.1 - 4.5 7.0 10.1 0.4 10.4 0.1 3.7 4 0 0 4 4 3 0 TPR repeat Pkinase PF00069.25 EAQ85335.1 - 1.2e-07 31.4 0.0 1.7e-07 30.8 0.0 1.3 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ85335.1 - 0.17 11.1 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Destabilase PF05497.12 EAQ85336.1 - 0.16 12.3 1.4 8.8 6.7 0.1 2.5 1 1 1 2 2 2 0 Destabilase Amidase PF01425.21 EAQ85337.1 - 5.1e-40 137.8 0.0 8.4e-39 133.8 0.1 2.0 2 0 0 2 2 2 2 Amidase Pab87_oct PF13969.6 EAQ85338.1 - 0.12 12.4 0.1 3.8 7.7 0.0 2.2 1 1 1 2 2 2 0 Pab87 octamerisation domain adh_short PF00106.25 EAQ85340.1 - 9.4e-22 77.4 0.0 4.8e-18 65.3 0.0 2.2 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EAQ85340.1 - 9.9e-13 48.2 0.0 1.9e-09 37.5 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EAQ85340.1 - 3.8e-05 23.7 0.2 9.5e-05 22.4 0.1 1.7 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 EAQ85340.1 - 0.034 13.6 0.0 0.068 12.6 0.0 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family SAM_MT PF04445.13 EAQ85340.1 - 0.059 12.8 0.1 0.085 12.3 0.1 1.2 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase 2-Hacid_dh_C PF02826.19 EAQ85340.1 - 0.1 12.0 0.0 0.21 10.9 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AATase PF07247.12 EAQ85341.1 - 0.0005 18.8 0.0 0.00074 18.2 0.0 1.2 1 0 0 1 1 1 1 Alcohol acetyltransferase ArsB PF02040.15 EAQ85344.1 - 6.1e-13 48.9 18.3 8.6e-08 31.9 5.9 2.2 2 0 0 2 2 2 2 Arsenical pump membrane protein Ank_2 PF12796.7 EAQ85345.1 - 3.3e-68 226.3 0.0 1.2e-17 64.3 0.0 4.9 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.30 EAQ85345.1 - 4.4e-44 147.1 0.0 2.3e-06 27.8 0.0 9.1 8 0 0 8 8 8 8 Ankyrin repeat Ank_5 PF13857.6 EAQ85345.1 - 3.2e-38 129.3 2.2 4.2e-10 39.7 0.0 6.4 3 2 3 6 6 6 6 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAQ85345.1 - 2.7e-34 117.1 0.0 7e-08 32.9 0.0 7.1 2 2 5 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAQ85345.1 - 8.5e-34 111.8 0.0 8.7e-06 25.7 0.0 8.8 8 0 0 8 8 8 7 Ankyrin repeat DUF4988 PF16378.5 EAQ85345.1 - 5.6e-07 29.4 0.7 0.016 14.9 0.1 2.6 1 1 1 2 2 2 2 Domain of unknown function TPR_14 PF13428.6 EAQ85345.1 - 0.34 11.9 4.5 14 6.8 2.1 3.7 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 EAQ85345.1 - 0.51 10.7 2.8 29 5.1 0.9 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 EAQ85345.1 - 0.99 9.6 5.8 7.7 6.8 0.4 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC4_WD40 PF12894.7 EAQ85347.1 - 3.4e-11 43.3 0.1 0.016 15.5 0.0 5.7 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 EAQ85347.1 - 7e-06 26.1 0.1 1.4e-05 25.1 0.1 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EAQ85347.1 - 6e-05 23.5 0.0 0.00018 21.9 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain WD40 PF00400.32 EAQ85347.1 - 0.00077 20.2 15.1 0.19 12.7 0.0 7.3 8 1 0 8 8 8 1 WD domain, G-beta repeat AAA_22 PF13401.6 EAQ85347.1 - 0.0021 18.3 0.0 0.0066 16.7 0.0 1.9 2 0 0 2 2 1 1 AAA domain Nbas_N PF15492.6 EAQ85347.1 - 0.0036 16.7 0.0 0.011 15.1 0.0 1.8 2 0 0 2 2 2 1 Neuroblastoma-amplified sequence, N terminal AAA_19 PF13245.6 EAQ85347.1 - 0.0081 16.5 0.0 0.017 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 EAQ85347.1 - 0.019 15.4 0.0 0.049 14.1 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 EAQ85347.1 - 0.037 14.2 0.0 0.094 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain Ion_trans_N PF08412.10 EAQ85347.1 - 0.061 12.9 0.4 0.31 10.7 0.0 2.3 2 0 0 2 2 2 0 Ion transport protein N-terminal NB-ARC PF00931.22 EAQ85347.1 - 0.062 12.5 0.0 0.13 11.4 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain MeaB PF03308.16 EAQ85347.1 - 0.079 11.9 0.1 0.26 10.2 0.0 1.7 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NTPase_1 PF03266.15 EAQ85347.1 - 0.092 12.7 0.0 0.27 11.1 0.0 1.8 1 0 0 1 1 1 0 NTPase AAA_7 PF12775.7 EAQ85347.1 - 0.13 11.7 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Fructosamin_kin PF03881.14 EAQ85348.1 - 1.1e-31 110.1 0.0 1.5e-31 109.7 0.0 1.1 1 0 0 1 1 1 1 Fructosamine kinase MFS_1 PF07690.16 EAQ85349.1 - 3.6e-10 39.3 5.7 3.6e-10 39.3 5.7 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EAQ85349.1 - 3.9e-08 32.6 1.0 6.1e-08 32.0 1.0 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.7 EAQ85349.1 - 0.0067 15.3 0.1 0.021 13.7 0.1 1.5 1 1 0 1 1 1 1 MFS_1 like family PP-binding PF00550.25 EAQ85350.1 - 2.1e-14 53.6 0.2 4.3e-14 52.6 0.2 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site WD40 PF00400.32 EAQ85350.1 - 2.1e-06 28.3 1.5 7.3e-06 26.6 0.4 2.6 2 0 0 2 2 2 1 WD domain, G-beta repeat PS-DH PF14765.6 EAQ85350.1 - 4.3e-06 26.2 0.0 7.6e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase ANAPC4_WD40 PF12894.7 EAQ85350.1 - 0.0044 17.3 0.0 0.0099 16.2 0.0 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EAQ85350.1 - 0.03 13.0 0.3 0.047 12.3 0.3 1.2 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Nbas_N PF15492.6 EAQ85350.1 - 0.14 11.4 0.1 0.29 10.4 0.1 1.4 1 0 0 1 1 1 0 Neuroblastoma-amplified sequence, N terminal p450 PF00067.22 EAQ85352.1 - 3.6e-23 82.1 0.0 4.2e-23 81.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Phytase-like PF13449.6 EAQ85353.1 - 3.5e-38 132.2 0.2 6.4e-38 131.3 0.1 1.5 1 1 0 1 1 1 1 Esterase-like activity of phytase SdiA-regulated PF06977.11 EAQ85353.1 - 0.07 12.4 0.0 1.6 7.9 0.0 2.4 2 0 0 2 2 2 0 SdiA-regulated CDC45 PF02724.14 EAQ85354.1 - 1.8 6.8 6.3 2.7 6.2 6.3 1.2 1 0 0 1 1 1 0 CDC45-like protein MULE PF10551.9 EAQ85356.1 - 9.5e-21 74.0 0.0 1.7e-20 73.2 0.0 1.4 1 0 0 1 1 1 1 MULE transposase domain DUF3416 PF11896.8 EAQ85356.1 - 0.0069 16.7 0.3 0.02 15.2 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3416) SWIM PF04434.17 EAQ85356.1 - 0.1 12.3 2.9 0.25 11.1 2.9 1.6 1 0 0 1 1 1 0 SWIM zinc finger Glyco_hydro_31 PF01055.26 EAQ85361.1 - 5.4e-95 319.2 1.7 2.1e-70 238.1 0.3 2.1 1 1 1 2 2 2 2 Glycosyl hydrolases family 31 Asp PF00026.23 EAQ85361.1 - 5.5e-48 164.0 0.0 8e-48 163.5 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EAQ85361.1 - 6.9e-09 36.2 0.0 1.7e-07 31.6 0.0 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EAQ85361.1 - 0.0067 17.0 0.1 3.7 8.3 0.0 3.1 2 1 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 EAQ85361.1 - 0.025 15.1 0.0 12 6.5 0.0 2.6 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Response_reg PF00072.24 EAQ85362.1 - 1.5e-06 28.3 0.0 2.6e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain Metallopep PF12044.8 EAQ85363.1 - 9.8e-112 373.7 0.0 6.5e-110 367.7 0.0 2.0 2 0 0 2 2 2 2 Putative peptidase family RNA_pol_Rpb1_R PF05001.13 EAQ85363.1 - 3.3 8.2 5.7 8.1 7.0 5.7 1.7 1 0 0 1 1 1 0 RNA polymerase Rpb1 C-terminal repeat Glycos_transf_1 PF00534.20 EAQ85365.1 - 8.7e-10 38.4 0.0 2.5e-09 36.9 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EAQ85365.1 - 2.2e-09 37.9 0.0 4.3e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 EAQ85365.1 - 0.0069 16.8 0.0 0.046 14.1 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 EAQ85365.1 - 0.0069 16.4 0.1 0.022 14.8 0.1 1.9 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_hydro_61 PF03443.14 EAQ85366.1 - 1.5e-38 132.8 0.0 5.9e-38 130.9 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.18 EAQ85366.1 - 4.4e-11 42.5 12.2 4.4e-11 42.5 12.2 2.4 2 0 0 2 2 2 1 Fungal cellulose binding domain Toxin_7 PF05980.12 EAQ85366.1 - 0.066 13.5 8.8 0.12 12.7 8.8 1.5 1 0 0 1 1 1 0 Toxin 7 MULE PF10551.9 EAQ85369.1 - 1.4e-24 86.3 0.4 5.8e-24 84.3 0.0 2.2 2 0 0 2 2 2 1 MULE transposase domain Transposase_mut PF00872.18 EAQ85369.1 - 0.0024 16.8 0.0 0.0057 15.6 0.0 1.6 1 0 0 1 1 1 1 Transposase, Mutator family DUF5575 PF17738.1 EAQ85369.1 - 0.035 13.2 0.0 0.07 12.2 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5575) UPF0203 PF05254.12 EAQ85369.1 - 1.5 9.1 4.3 42 4.5 0.0 3.6 3 1 0 3 3 3 0 Uncharacterised protein family (UPF0203) Cutinase PF01083.22 EAQ85371.1 - 5.7e-31 107.8 0.2 7.5e-27 94.4 0.1 2.1 1 1 1 2 2 2 2 Cutinase VirJ PF06057.11 EAQ85371.1 - 0.015 15.2 0.0 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) PE-PPE PF08237.11 EAQ85371.1 - 0.1 12.1 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 PE-PPE domain LCCL PF03815.19 EAQ85371.1 - 0.14 12.2 0.0 0.36 11.0 0.0 1.6 1 0 0 1 1 1 0 LCCL domain Ank_2 PF12796.7 EAQ85372.1 - 4.8e-29 100.8 0.0 2.6e-09 37.5 0.0 4.9 3 2 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAQ85372.1 - 2e-28 95.3 2.1 0.0036 17.7 0.0 8.4 8 0 0 8 8 8 6 Ankyrin repeat Ank PF00023.30 EAQ85372.1 - 2.8e-28 97.1 2.3 0.01 16.2 0.0 9.0 8 1 0 8 8 8 6 Ankyrin repeat Ank_4 PF13637.6 EAQ85372.1 - 5.4e-28 97.0 4.0 2.4e-06 28.0 0.2 7.3 4 2 3 7 7 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAQ85372.1 - 6e-20 71.1 2.7 0.001 19.3 0.0 6.6 6 0 0 6 6 6 4 Ankyrin repeats (many copies) zf-U1 PF06220.12 EAQ85372.1 - 1.3e-05 24.9 0.1 2.5e-05 23.9 0.1 1.6 1 0 0 1 1 1 1 U1 zinc finger F-box-like PF12937.7 EAQ85372.1 - 4.3e-05 23.3 1.2 0.00011 22.0 1.2 1.7 1 0 0 1 1 1 1 F-box-like YcaO PF02624.16 EAQ85372.1 - 0.048 12.9 0.2 0.096 11.9 0.0 1.5 2 0 0 2 2 2 0 YcaO cyclodehydratase, ATP-ad Mg2+-binding F-box_4 PF15966.5 EAQ85372.1 - 0.12 12.3 0.8 0.23 11.3 0.1 1.8 2 0 0 2 2 2 0 F-box DUF3306 PF11748.8 EAQ85372.1 - 1.2 10.0 6.0 0.16 12.8 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) MARVEL PF01284.23 EAQ85374.1 - 1e-05 25.6 17.7 5.6e-05 23.2 17.7 2.0 1 1 0 1 1 1 1 Membrane-associating domain DUF588 PF04535.12 EAQ85374.1 - 0.74 9.6 11.1 0.039 13.7 3.7 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF588) DUF3040 PF11239.8 EAQ85374.1 - 2.1 8.7 4.4 1.2 9.5 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) Peptidase_M56 PF05569.11 EAQ85374.1 - 2.2 7.4 8.0 0.17 11.1 2.4 1.9 2 1 0 2 2 2 0 BlaR1 peptidase M56 p450 PF00067.22 EAQ85378.1 - 3.9e-40 138.0 0.0 5.3e-40 137.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EAQ85381.1 - 2.3e-27 95.9 0.0 3e-27 95.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF4234 PF14018.6 EAQ85382.1 - 5.6 7.2 6.6 16 5.7 6.6 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4234) p450 PF00067.22 EAQ85383.1 - 1.8e-20 73.2 0.0 2.2e-20 72.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 EAQ85384.1 - 1.3e-41 142.7 54.9 4.5e-41 140.9 52.3 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily GST_N PF02798.20 EAQ85385.1 - 4.9e-14 52.4 0.0 9.2e-14 51.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EAQ85385.1 - 2.1e-10 40.9 0.0 3.9e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EAQ85385.1 - 6.8e-09 35.9 0.0 1.5e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EAQ85385.1 - 7.8e-09 35.4 0.2 1.3e-08 34.7 0.2 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EAQ85385.1 - 8.3e-09 35.6 0.0 1.4e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EAQ85385.1 - 1.1e-06 28.7 0.0 1.9e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Prenyltrans PF00432.21 EAQ85386.1 - 0.018 14.8 0.6 1 9.2 0.0 3.7 4 0 0 4 4 4 0 Prenyltransferase and squalene oxidase repeat NTP_transferase PF00483.23 EAQ85387.1 - 7.6e-33 114.1 0.0 1.1e-32 113.6 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 EAQ85387.1 - 1.8e-07 30.6 2.1 0.00026 20.6 0.0 3.4 3 0 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 EAQ85387.1 - 6.6e-07 29.8 0.0 9.9e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.19 EAQ85387.1 - 0.019 14.7 0.0 0.036 13.8 0.0 1.4 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Fucokinase PF07959.12 EAQ85387.1 - 0.019 13.9 0.3 3.8 6.4 0.0 2.2 2 0 0 2 2 2 0 L-fucokinase Glyco_tranf_2_3 PF13641.6 EAQ85387.1 - 0.038 13.9 0.0 0.071 13.0 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Dynamin_N PF00350.23 EAQ85388.1 - 1.7e-24 86.8 0.0 1.7e-23 83.5 0.0 2.4 1 1 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 EAQ85388.1 - 2.4e-12 46.7 0.0 1.2e-07 31.2 0.0 2.4 2 0 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.23 EAQ85388.1 - 0.00057 20.0 0.0 0.34 11.0 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase GED PF02212.18 EAQ85388.1 - 0.0011 19.1 0.0 0.0027 17.8 0.0 1.7 1 0 0 1 1 1 1 Dynamin GTPase effector domain ABC_tran PF00005.27 EAQ85388.1 - 0.029 14.9 0.0 0.08 13.5 0.0 1.8 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 EAQ85388.1 - 0.044 13.5 0.6 0.11 12.3 0.1 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_21 PF13304.6 EAQ85388.1 - 0.052 13.4 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Roc PF08477.13 EAQ85388.1 - 0.052 13.8 0.0 1.2 9.3 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase TFIID_NTD2 PF04494.15 EAQ85388.1 - 0.12 12.6 0.1 0.29 11.4 0.1 1.6 1 0 0 1 1 1 0 WD40 associated region in TFIID subunit, NTD2 domain LexA_DNA_bind PF01726.16 EAQ85388.1 - 0.17 11.7 1.1 9 6.2 0.0 2.8 2 0 0 2 2 2 0 LexA DNA binding domain Sacchrp_dh_C PF16653.5 EAQ85389.1 - 1.4e-19 71.3 0.0 1.7e-19 71.0 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 EAQ85389.1 - 4e-06 27.1 0.3 8.4e-06 26.1 0.0 1.6 1 1 1 2 2 2 1 Saccharopine dehydrogenase NADP binding domain IBR PF01485.21 EAQ85390.1 - 0.00078 19.6 6.6 0.00078 19.6 6.6 4.5 4 1 0 4 4 4 1 IBR domain, a half RING-finger domain VWA_2 PF13519.6 EAQ85390.1 - 0.037 14.7 0.0 0.072 13.7 0.0 1.5 1 0 0 1 1 1 0 von Willebrand factor type A domain RVT_1 PF00078.27 EAQ85391.1 - 1.5e-11 44.2 0.0 2e-10 40.5 0.0 2.2 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) SKG6 PF08693.10 EAQ85392.1 - 0.00056 19.3 1.2 0.00056 19.3 1.2 1.8 2 0 0 2 2 2 1 Transmembrane alpha-helix domain DUF4448 PF14610.6 EAQ85392.1 - 0.1 12.4 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) LAMTOR PF15454.6 EAQ85393.1 - 1.7e-09 38.1 0.5 2.8e-09 37.4 0.5 1.4 1 0 0 1 1 1 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator DUF713 PF05218.14 EAQ85393.1 - 0.045 13.5 0.0 0.065 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF713) DUF3618 PF12277.8 EAQ85393.1 - 0.054 13.8 1.4 0.11 12.8 1.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3618) FlaC_arch PF05377.11 EAQ85393.1 - 0.081 13.3 0.1 0.15 12.5 0.1 1.4 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) T2SSI PF02501.17 EAQ85394.1 - 0.011 15.9 0.1 0.017 15.3 0.1 1.2 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein I RPEL PF02755.15 EAQ85395.1 - 0.00098 18.7 5.3 0.021 14.5 0.0 2.9 3 0 0 3 3 3 2 RPEL repeat zf-C2H2_jaz PF12171.8 EAQ85396.1 - 6.4e-05 23.1 0.1 0.00011 22.4 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EAQ85396.1 - 0.0059 17.0 0.2 0.0093 16.3 0.2 1.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 EAQ85396.1 - 0.0065 16.8 0.1 0.011 16.0 0.1 1.3 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) DUF1974 PF09317.11 EAQ85396.1 - 0.019 14.5 0.8 0.032 13.8 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1974) Med7 PF05983.11 EAQ85397.1 - 1.5e-54 185.0 0.1 1.8e-54 184.7 0.1 1.1 1 0 0 1 1 1 1 MED7 protein SPOC PF07744.13 EAQ85398.1 - 2.7e-27 95.6 0.0 4.6e-27 94.8 0.0 1.4 1 0 0 1 1 1 1 SPOC domain TFIIS_M PF07500.14 EAQ85398.1 - 6.2e-19 68.5 0.1 1.7e-18 67.1 0.1 1.7 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain PHD PF00628.29 EAQ85398.1 - 8.2e-10 38.4 7.9 1.6e-09 37.5 7.9 1.5 1 0 0 1 1 1 1 PHD-finger zf-CW PF07496.15 EAQ85398.1 - 0.1 12.6 2.3 0.22 11.6 2.3 1.5 1 0 0 1 1 1 0 CW-type Zinc Finger PHD_2 PF13831.6 EAQ85398.1 - 0.23 11.1 3.4 0.44 10.1 3.4 1.4 1 0 0 1 1 1 0 PHD-finger Proteasome PF00227.26 EAQ85399.1 - 1.2e-60 204.2 0.1 1.5e-60 203.9 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EAQ85399.1 - 1.4e-13 50.2 0.1 4.5e-13 48.6 0.2 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DUF5624 PF18538.1 EAQ85399.1 - 0.014 15.5 0.4 0.04 14.0 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5624) Nitrate_red_gam PF02665.14 EAQ85399.1 - 0.024 14.2 0.0 0.036 13.6 0.0 1.2 1 0 0 1 1 1 0 Nitrate reductase gamma subunit PAP2 PF01569.21 EAQ85400.1 - 2.9e-24 85.4 0.8 2.9e-24 85.4 0.8 1.7 2 0 0 2 2 2 1 PAP2 superfamily YhhN PF07947.14 EAQ85400.1 - 0.6 9.7 6.4 2.1 7.9 2.6 2.8 2 1 0 2 2 2 0 YhhN family WD40 PF00400.32 EAQ85401.1 - 2.7e-40 135.6 19.8 2.5e-05 24.9 0.0 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.7 EAQ85401.1 - 9e-11 41.5 0.2 1.8e-10 40.6 0.2 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EAQ85401.1 - 2.4e-10 40.0 0.6 1.1e-09 37.9 0.4 2.2 1 1 1 2 2 2 1 F-box domain ANAPC4_WD40 PF12894.7 EAQ85401.1 - 7.3e-06 26.2 1.4 5.2 7.4 0.0 5.5 2 2 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 EAQ85401.1 - 0.00022 20.9 0.5 0.012 15.2 0.5 2.7 1 1 0 1 1 1 1 PQQ-like domain Nup160 PF11715.8 EAQ85401.1 - 0.0038 16.0 4.7 13 4.3 0.1 4.8 2 1 3 5 5 5 3 Nucleoporin Nup120/160 F-box_4 PF15966.5 EAQ85401.1 - 0.0094 15.8 0.0 0.029 14.3 0.0 1.8 1 0 0 1 1 1 1 F-box DUF4597 PF15366.6 EAQ85401.1 - 0.12 12.1 1.3 1.3 8.9 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4597) DUF5046 PF16465.5 EAQ85401.1 - 0.18 11.2 0.4 25 4.2 0.0 3.3 2 2 1 3 3 3 0 Domain of unknown function (DUF5046) ADH_N PF08240.12 EAQ85403.1 - 1.6e-28 98.7 3.3 2.8e-28 98.0 3.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EAQ85403.1 - 9e-12 45.1 0.0 2.3e-11 43.8 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 EAQ85403.1 - 0.001 18.5 0.5 0.0016 17.8 0.5 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.6 EAQ85403.1 - 0.0083 17.2 0.0 0.013 16.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Y_Y_Y PF07495.13 EAQ85403.1 - 0.013 15.4 0.2 0.93 9.5 0.0 2.3 2 0 0 2 2 2 0 Y_Y_Y domain ETF PF01012.21 EAQ85403.1 - 0.031 14.2 0.0 0.18 11.7 0.0 2.0 2 0 0 2 2 2 0 Electron transfer flavoprotein domain Epimerase PF01370.21 EAQ85404.1 - 6.2e-14 52.0 0.1 2.4e-13 50.1 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EAQ85404.1 - 1.5e-09 37.7 0.1 4.4e-09 36.2 0.0 1.7 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 EAQ85404.1 - 6.2e-09 35.4 0.1 0.003 16.8 0.0 2.9 3 0 0 3 3 3 2 Male sterility protein 3Beta_HSD PF01073.19 EAQ85404.1 - 1.3e-08 34.2 0.0 3.1e-08 33.0 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 EAQ85404.1 - 1e-06 28.3 0.0 2.1e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.6 EAQ85404.1 - 2.7e-06 27.4 1.0 5.5e-06 26.4 0.1 2.0 2 1 0 2 2 2 1 NAD(P)H-binding KR PF08659.10 EAQ85404.1 - 5.1e-06 26.5 0.0 8.2e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 KR domain NmrA PF05368.13 EAQ85404.1 - 1.2e-05 25.0 0.1 0.00011 21.9 0.0 2.3 3 0 0 3 3 3 1 NmrA-like family Polysacc_synt_2 PF02719.15 EAQ85404.1 - 0.0042 16.3 0.1 0.0057 15.8 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 EAQ85404.1 - 0.096 11.8 0.0 0.23 10.5 0.0 1.6 2 0 0 2 2 2 0 RmlD substrate binding domain Sugar_tr PF00083.24 EAQ85405.1 - 1.2e-109 367.2 16.7 1.5e-109 366.8 16.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EAQ85405.1 - 4.8e-26 91.5 13.1 4.8e-26 91.5 13.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 EAQ85405.1 - 0.042 12.2 4.7 0.33 9.3 0.2 2.2 2 0 0 2 2 2 0 Transmembrane secretion effector Zn_clus PF00172.18 EAQ85406.1 - 2.3e-10 40.4 9.8 4e-10 39.6 9.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EAQ85406.1 - 0.0004 19.5 2.9 0.016 14.2 2.9 2.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain MR_MLE_C PF13378.6 EAQ85407.1 - 6.9e-33 114.1 0.8 9.1e-18 64.6 0.1 2.1 2 0 0 2 2 2 2 Enolase C-terminal domain-like GATase PF00117.28 EAQ85408.1 - 6.8e-05 22.7 0.0 9.3e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I ImpE PF07024.13 EAQ85408.1 - 0.11 12.6 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 ImpE protein Sugar_tr PF00083.24 EAQ85409.1 - 3.7e-76 256.8 22.8 4.1e-76 256.7 22.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EAQ85409.1 - 1.9e-17 63.2 30.6 1.9e-17 63.2 30.6 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily PAN_4 PF14295.6 EAQ85410.1 - 2.6e-05 24.0 0.0 4.9e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 PAN domain PAN_3 PF08277.12 EAQ85410.1 - 0.047 13.5 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 PAN-like domain tRNA-synt_1e PF01406.19 EAQ85412.1 - 3.9e-104 348.2 0.0 6.7e-104 347.5 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 EAQ85412.1 - 0.0013 17.6 1.1 0.34 9.6 0.1 2.5 2 0 0 2 2 2 2 tRNA synthetases class I (M) DALR_2 PF09190.11 EAQ85412.1 - 0.0027 18.1 0.0 0.0092 16.4 0.0 2.0 1 0 0 1 1 1 1 DALR domain tRNA-synt_1c PF00749.21 EAQ85412.1 - 0.016 14.1 0.0 0.016 14.1 0.0 1.8 2 0 0 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain Ribosomal_L22 PF00237.19 EAQ85412.1 - 0.039 14.2 0.1 0.17 12.1 0.1 2.0 1 0 0 1 1 1 0 Ribosomal protein L22p/L17e Nuc_deoxyri_tr2 PF15891.5 EAQ85413.1 - 2.5e-32 111.4 0.0 3.2e-32 111.0 0.0 1.1 1 0 0 1 1 1 1 Nucleoside 2-deoxyribosyltransferase like DUF3716 PF12511.8 EAQ85414.1 - 4.5e-15 55.4 3.4 8.5e-15 54.5 3.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) Terpene_synth_C PF03936.16 EAQ85416.1 - 0.2 11.0 0.0 0.3 10.4 0.0 1.2 1 0 0 1 1 1 0 Terpene synthase family, metal binding domain Gpi16 PF04113.14 EAQ85417.1 - 8.5e-248 823.4 0.0 1e-247 823.1 0.0 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component FUSC PF04632.12 EAQ85417.1 - 0.043 12.3 0.6 0.065 11.8 0.6 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family LUC7 PF03194.15 EAQ85418.1 - 1e-54 185.9 0.5 3.9e-27 95.5 0.0 2.0 1 1 1 2 2 2 2 LUC7 N_terminus TFIIA PF03153.13 EAQ85419.1 - 6.6 6.6 14.5 10 6.0 14.5 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit GMC_oxred_N PF00732.19 EAQ85420.1 - 3.3e-47 161.3 0.0 4.3e-47 160.9 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EAQ85420.1 - 2.8e-28 99.2 0.1 6.1e-28 98.1 0.1 1.6 1 0 0 1 1 1 1 GMC oxidoreductase Thi4 PF01946.17 EAQ85420.1 - 0.00018 20.8 0.0 0.00031 20.1 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 EAQ85420.1 - 0.00022 20.4 0.0 0.00034 19.8 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 EAQ85420.1 - 0.0011 18.6 0.1 0.0049 16.5 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EAQ85420.1 - 0.003 17.7 0.1 0.0098 16.1 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EAQ85420.1 - 0.0042 16.2 0.0 0.0083 15.3 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain Malic_M PF03949.15 EAQ85420.1 - 0.024 13.9 0.1 0.041 13.2 0.1 1.3 1 0 0 1 1 1 0 Malic enzyme, NAD binding domain K_oxygenase PF13434.6 EAQ85420.1 - 0.034 13.3 0.0 0.058 12.5 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.14 EAQ85420.1 - 0.079 11.8 0.1 0.11 11.3 0.1 1.1 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox_2 PF07992.14 EAQ85420.1 - 0.081 12.1 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 EAQ85420.1 - 0.11 12.8 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_9 PF13454.6 EAQ85420.1 - 0.14 12.1 0.1 0.33 10.9 0.0 1.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding Serglycin PF04360.12 EAQ85422.1 - 0.054 13.4 7.6 0.11 12.4 7.6 1.5 1 0 0 1 1 1 0 Serglycin E1_DerP2_DerF2 PF02221.15 EAQ85422.1 - 0.058 13.8 0.0 0.099 13.1 0.0 1.4 1 0 0 1 1 1 0 ML domain LPMO_10 PF03067.15 EAQ85422.1 - 0.11 13.2 0.0 0.2 12.3 0.0 1.4 1 0 0 1 1 1 0 Lytic polysaccharide mono-oxygenase, cellulose-degrading GFO_IDH_MocA PF01408.22 EAQ85423.1 - 6.1e-14 52.9 0.0 1.1e-13 52.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Abhydrolase_6 PF12697.7 EAQ85423.1 - 9.9e-05 23.0 2.0 0.00022 21.9 2.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family GFO_IDH_MocA_C PF02894.17 EAQ85423.1 - 0.0017 18.4 0.0 0.0036 17.3 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Abhydrolase_1 PF00561.20 EAQ85423.1 - 0.025 14.3 0.0 0.043 13.4 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EAQ85423.1 - 0.062 12.5 0.0 5.6 6.1 0.0 2.6 3 0 0 3 3 3 0 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 EAQ85424.1 - 1.1e-15 57.6 0.6 6e-15 55.2 0.1 2.2 2 0 0 2 2 2 1 TAP-like protein Abhydrolase_1 PF00561.20 EAQ85424.1 - 4.1e-10 39.7 0.0 3.8e-06 26.7 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold DAO PF01266.24 EAQ85425.1 - 2e-22 80.3 6.6 2.3e-22 80.1 6.6 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EAQ85425.1 - 0.026 14.7 0.0 0.11 12.7 0.0 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Sacchrp_dh_NADP PF03435.18 EAQ85425.1 - 0.056 13.7 0.0 0.25 11.6 0.0 2.0 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain p450 PF00067.22 EAQ85426.1 - 2.2e-56 191.5 0.0 7.8e-56 189.7 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 Terpene_synth_C PF03936.16 EAQ85427.1 - 0.0021 17.4 0.0 0.0052 16.2 0.0 1.6 2 0 0 2 2 2 1 Terpene synthase family, metal binding domain Epimerase PF01370.21 EAQ85427.1 - 0.0022 17.5 0.0 0.0033 16.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 EAQ85427.1 - 0.052 12.7 0.0 3 7.0 0.0 2.2 2 0 0 2 2 2 0 Male sterility protein DEAD PF00270.29 EAQ85428.1 - 1.6e-26 93.2 0.0 2.9e-26 92.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Sec63 PF02889.16 EAQ85428.1 - 4.5e-16 58.8 0.0 2.2e-12 46.7 0.0 2.2 1 1 1 2 2 2 2 Sec63 Brl domain ResIII PF04851.15 EAQ85428.1 - 2e-13 50.7 0.0 5.1e-13 49.4 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EAQ85428.1 - 4.7e-10 39.8 0.0 1.2e-08 35.3 0.0 2.6 2 1 0 2 2 2 1 Helicase conserved C-terminal domain AAA_19 PF13245.6 EAQ85428.1 - 0.00018 21.8 0.1 0.0018 18.6 0.1 2.6 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EAQ85428.1 - 0.001 18.8 0.0 0.0022 17.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.6 EAQ85428.1 - 0.0018 18.8 0.5 0.015 15.9 0.0 2.6 3 0 0 3 3 3 1 Helix-hairpin-helix domain UvrD-helicase PF00580.21 EAQ85428.1 - 0.0019 17.8 0.1 0.06 12.9 0.0 2.5 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_22 PF13401.6 EAQ85428.1 - 0.011 16.1 0.0 0.029 14.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 EAQ85428.1 - 0.016 14.3 0.0 0.028 13.5 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein SPT6_acidic PF14632.6 EAQ85428.1 - 4.4 8.0 6.7 12 6.6 0.0 3.0 3 0 0 3 3 3 0 Acidic N-terminal SPT6 NACHT_N PF17100.5 EAQ85429.1 - 9.1e-25 87.8 0.0 1e-15 58.2 0.0 2.2 1 1 1 2 2 2 2 N-terminal domain of NWD NACHT-NTPase NACHT PF05729.12 EAQ85429.1 - 1.3e-10 41.5 0.2 2.1e-10 40.8 0.2 1.3 1 0 0 1 1 1 1 NACHT domain Plant_zn_clust PF10533.9 EAQ85430.1 - 0.043 13.8 0.6 0.095 12.7 0.6 1.6 1 0 0 1 1 1 0 Plant zinc cluster domain Exo_endo_phos PF03372.23 EAQ85431.1 - 2.8e-05 23.8 0.0 6.9e-05 22.5 0.0 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF4500 PF14937.6 EAQ85432.1 - 0.056 13.5 0.1 0.1 12.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4500) Nuc_sug_transp PF04142.15 EAQ85434.1 - 5.9e-101 337.8 5.9 8.1e-101 337.3 5.9 1.1 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 EAQ85434.1 - 8.4e-07 29.2 26.1 0.00048 20.3 6.1 2.6 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 EAQ85434.1 - 1.3e-06 27.9 11.8 1.2e-05 24.7 11.7 2.1 1 1 0 1 1 1 1 UAA transporter family TPT PF03151.16 EAQ85434.1 - 2.7e-05 23.7 14.7 0.0087 15.4 5.1 2.5 2 1 0 2 2 2 2 Triose-phosphate Transporter family DUF1129 PF06570.11 EAQ85434.1 - 0.041 13.4 0.3 0.72 9.3 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1129) Halogen_Hydrol PF10112.9 EAQ85434.1 - 0.081 12.9 1.1 3 7.8 0.2 2.4 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein CNDH2_M PF16869.5 EAQ85435.1 - 0.43 11.3 8.9 0.042 14.6 1.5 3.2 3 0 0 3 3 3 0 PF16858 DUF4448 PF14610.6 EAQ85436.1 - 1.7e-09 37.8 0.0 6.8e-08 32.5 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF4448) Adhesin_P1 PF03257.13 EAQ85436.1 - 0.083 13.4 2.7 0.34 11.5 2.7 2.0 1 1 0 1 1 1 0 Mycoplasma adhesin P1 Phytase-like PF13449.6 EAQ85440.1 - 0.03 14.3 0.0 0.11 12.5 0.0 1.9 2 0 0 2 2 2 0 Esterase-like activity of phytase NHL PF01436.21 EAQ85440.1 - 0.052 13.6 0.0 25 5.1 0.0 4.3 4 0 0 4 4 4 0 NHL repeat LysM PF01476.20 EAQ85442.1 - 1.3e-32 111.6 0.0 5.1e-08 32.8 0.0 6.3 6 0 0 6 6 6 6 LysM domain CC PF04942.14 EAQ85442.1 - 0.068 13.4 5.2 44 4.4 0.1 4.4 3 0 0 3 3 3 0 CC domain Glyco_hydro_18 PF00704.28 EAQ85443.1 - 4e-62 210.7 0.0 5.4e-62 210.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 EAQ85443.1 - 2.3e-09 37.6 9.3 2.3e-09 37.6 9.3 5.8 7 2 0 7 7 7 2 Chitin recognition protein Acetyltransf_2 PF00797.17 EAQ85444.1 - 6.1e-48 163.7 0.0 8.4e-48 163.2 0.0 1.2 1 0 0 1 1 1 1 N-acetyltransferase Transglut_core PF01841.19 EAQ85444.1 - 0.0092 16.4 0.0 0.02 15.4 0.0 1.7 2 0 0 2 2 2 1 Transglutaminase-like superfamily p450 PF00067.22 EAQ85445.1 - 4.1e-42 144.5 0.0 5.5e-42 144.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 VCBS PF13517.6 EAQ85446.1 - 1e-26 93.3 59.9 2.5e-13 50.4 2.2 7.7 4 2 5 9 9 9 7 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Lipase_GDSL_2 PF13472.6 EAQ85446.1 - 5e-17 62.9 1.0 5.4e-16 59.5 1.2 2.6 2 1 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EAQ85446.1 - 6.6e-08 32.8 0.0 1.3e-07 31.8 0.0 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase TcdB_toxin_midN PF12256.8 EAQ85446.1 - 0.00014 21.3 7.5 0.49 9.8 0.0 6.1 5 2 3 8 8 8 2 Insecticide toxin TcdB middle/N-terminal region FG-GAP PF01839.23 EAQ85446.1 - 0.0013 18.8 30.2 0.24 11.6 0.1 6.8 6 0 0 6 6 6 3 FG-GAP repeat Lipase_GDSL_3 PF14606.6 EAQ85446.1 - 0.018 15.2 0.1 0.099 12.8 0.0 2.0 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family Pectate_lyase_3 PF12708.7 EAQ85448.1 - 8.5e-97 323.2 7.9 1.6e-84 283.1 0.9 3.2 3 0 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 EAQ85448.1 - 9.7e-07 28.4 1.7 0.048 13.3 0.1 2.9 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase NosD PF05048.13 EAQ85448.1 - 0.028 13.7 0.5 0.087 12.1 0.2 1.7 1 1 0 1 1 1 0 Periplasmic copper-binding protein (NosD) YopD PF05844.12 EAQ85453.1 - 0.61 9.1 5.2 0.069 12.1 0.7 1.6 2 0 0 2 2 2 0 YopD protein Acetyltransf_10 PF13673.7 EAQ85454.1 - 2.8e-08 33.8 0.0 4.1e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EAQ85454.1 - 9.9e-07 29.0 0.0 1.6e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EAQ85454.1 - 3e-05 24.4 0.0 5.8e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain AvrE_T3Es PF11725.8 EAQ85454.1 - 0.53 7.4 1.9 0.66 7.1 1.9 1.0 1 0 0 1 1 1 0 AvrE-family Type-III effector proteins (T3Es) AltA1 PF16541.5 EAQ85455.1 - 0.00077 20.3 0.1 0.0027 18.5 0.1 1.9 1 0 0 1 1 1 1 Alternaria alternata allergen 1 DUF1996 PF09362.10 EAQ85456.1 - 4.3e-83 278.9 0.4 5.3e-83 278.6 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) MFS_1 PF07690.16 EAQ85457.1 - 3.4e-21 75.6 50.3 2.3e-20 72.8 46.3 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EAQ85457.1 - 1e-07 30.8 25.3 1.6e-07 30.2 25.3 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) ECH_1 PF00378.20 EAQ85458.1 - 5.5e-47 160.2 0.0 2.3e-31 109.0 0.0 2.1 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EAQ85458.1 - 3.7e-25 89.1 0.1 3.2e-12 46.6 0.2 3.0 2 1 1 3 3 3 3 Enoyl-CoA hydratase/isomerase Acetyltransf_8 PF13523.6 EAQ85459.1 - 6.3e-37 126.5 0.2 1.1e-17 64.0 0.0 2.1 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain ABC_membrane PF00664.23 EAQ85460.1 - 1.3e-88 297.3 23.6 6.6e-48 163.7 5.7 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EAQ85460.1 - 1.4e-62 210.2 0.0 6e-32 111.0 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EAQ85460.1 - 2.2e-14 53.4 1.2 0.00082 18.9 0.0 4.3 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EAQ85460.1 - 1.7e-08 34.1 0.3 0.0014 18.3 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 EAQ85460.1 - 4.9e-08 33.3 0.4 0.095 13.0 0.0 3.9 3 1 0 3 3 3 2 AAA domain AAA_16 PF13191.6 EAQ85460.1 - 2.7e-07 31.1 2.5 0.023 15.1 0.0 3.1 2 1 0 2 2 2 2 AAA ATPase domain AAA_30 PF13604.6 EAQ85460.1 - 3.5e-06 26.9 2.0 0.065 12.9 0.0 3.8 3 1 0 3 3 3 2 AAA domain DUF87 PF01935.17 EAQ85460.1 - 1.8e-05 25.0 0.1 0.018 15.1 0.0 2.3 2 0 0 2 2 2 2 Helicase HerA, central domain ABC_ATPase PF09818.9 EAQ85460.1 - 2.3e-05 23.4 0.5 0.083 11.7 0.0 2.5 2 0 0 2 2 2 2 Predicted ATPase of the ABC class RsgA_GTPase PF03193.16 EAQ85460.1 - 7.8e-05 22.6 0.0 0.095 12.6 0.0 3.0 3 0 0 3 3 3 1 RsgA GTPase Zeta_toxin PF06414.12 EAQ85460.1 - 8.2e-05 22.0 0.0 0.11 11.7 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin AAA_25 PF13481.6 EAQ85460.1 - 8.7e-05 22.2 0.7 0.87 9.1 0.0 4.1 4 0 0 4 4 4 1 AAA domain AAA_21 PF13304.6 EAQ85460.1 - 0.0004 20.3 0.6 0.76 9.5 0.0 3.7 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EAQ85460.1 - 0.00052 20.6 0.2 0.38 11.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain DUF3987 PF13148.6 EAQ85460.1 - 0.00093 18.3 0.1 0.18 10.8 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3987) AAA PF00004.29 EAQ85460.1 - 0.0012 19.3 0.2 17 5.8 0.1 4.2 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 EAQ85460.1 - 0.0014 18.8 0.4 2.4 8.3 0.1 2.7 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 EAQ85460.1 - 0.0026 18.3 0.0 4.3 7.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain APS_kinase PF01583.20 EAQ85460.1 - 0.0039 17.1 0.0 3.7 7.4 0.0 2.5 2 0 0 2 2 2 2 Adenylylsulphate kinase DEAD PF00270.29 EAQ85460.1 - 0.0071 16.1 0.5 0.054 13.3 0.0 2.6 3 1 0 3 3 3 1 DEAD/DEAH box helicase AAA_5 PF07728.14 EAQ85460.1 - 0.017 15.2 0.0 5.5 7.0 0.0 2.8 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) Cytochrome-c551 PF10643.9 EAQ85460.1 - 0.018 14.6 1.9 0.05 13.2 1.9 1.7 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 SRP54 PF00448.22 EAQ85460.1 - 0.018 14.7 0.0 6.3 6.4 0.0 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_15 PF13175.6 EAQ85460.1 - 0.021 14.6 0.0 1.2 8.7 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain MMR_HSR1 PF01926.23 EAQ85460.1 - 0.051 13.7 0.0 8 6.6 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_17 PF13207.6 EAQ85460.1 - 0.078 13.4 0.0 16 5.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EAQ85460.1 - 0.089 12.3 0.1 15 5.1 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region HipN PF18253.1 EAQ85460.1 - 0.091 12.5 0.0 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 Hsp70-interacting protein N N-terminal domain SbcCD_C PF13558.6 EAQ85460.1 - 0.1 12.9 3.5 10 6.5 0.1 3.8 3 2 0 3 3 3 0 Putative exonuclease SbcCD, C subunit AAA_24 PF13479.6 EAQ85460.1 - 0.18 11.5 0.1 11 5.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 EAQ85460.1 - 0.2 10.8 0.1 10 5.2 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain TM140 PF14985.6 EAQ85460.1 - 0.54 9.8 8.8 0.2 11.2 3.4 2.5 2 0 0 2 2 2 0 TM140 protein family Condensation PF00668.20 EAQ85461.1 - 2.8e-47 161.5 0.0 3.5e-27 95.2 0.0 2.8 2 1 0 2 2 2 2 Condensation domain AMP-binding PF00501.28 EAQ85461.1 - 1.9e-40 138.7 0.0 1e-39 136.4 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme PP-binding PF00550.25 EAQ85461.1 - 3.7e-25 88.0 0.0 2.7e-11 43.7 0.1 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EAQ85461.1 - 0.0004 21.3 0.1 0.12 13.4 0.1 3.2 2 1 0 2 2 2 1 AMP-binding enzyme C-terminal domain DUF1749 PF08538.10 EAQ85462.1 - 1.3e-66 224.7 0.0 1.6e-66 224.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.7 EAQ85462.1 - 0.0012 19.5 1.3 0.0014 19.3 1.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EAQ85462.1 - 0.015 14.6 0.0 0.027 13.7 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 PGAP1 PF07819.13 EAQ85462.1 - 0.07 12.8 0.0 0.097 12.4 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Peptidase_S9 PF00326.21 EAQ85462.1 - 0.12 11.8 0.0 0.26 10.7 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF900 PF05990.12 EAQ85462.1 - 0.15 11.5 0.0 0.2 11.1 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Fructosamin_kin PF03881.14 EAQ85463.1 - 2.6e-20 72.8 0.0 3.5e-20 72.4 0.0 1.1 1 0 0 1 1 1 1 Fructosamine kinase DUF1679 PF07914.11 EAQ85463.1 - 0.04 12.8 0.0 0.072 11.9 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1679) MULE PF10551.9 EAQ85464.1 - 1.4e-24 86.3 0.4 5.8e-24 84.3 0.0 2.2 2 0 0 2 2 2 1 MULE transposase domain Transposase_mut PF00872.18 EAQ85464.1 - 0.0025 16.7 0.0 0.0057 15.6 0.0 1.5 1 0 0 1 1 1 1 Transposase, Mutator family DUF5575 PF17738.1 EAQ85464.1 - 0.037 13.1 0.0 0.07 12.2 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5575) SHMT PF00464.19 EAQ85465.1 - 1e-23 83.6 0.0 1.2e-23 83.3 0.0 1.1 1 0 0 1 1 1 1 Serine hydroxymethyltransferase TMF_TATA_bd PF12325.8 EAQ85465.1 - 0.051 13.8 0.1 0.086 13.1 0.1 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DUF4360 PF14273.6 EAQ85468.1 - 1.1e-16 61.2 0.1 2.9e-11 43.6 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4360) RTA1 PF04479.13 EAQ85469.1 - 1.5e-71 240.2 6.8 1.5e-71 240.2 6.8 1.4 2 0 0 2 2 2 1 RTA1 like protein DUF543 PF04418.12 EAQ85469.1 - 0.11 12.5 1.0 0.36 10.8 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF543) DUF996 PF06195.13 EAQ85469.1 - 0.7 10.2 8.1 0.78 10.0 0.8 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF996) HEAT_EZ PF13513.6 EAQ85470.1 - 2.1e-17 63.3 10.7 5.8e-07 29.9 0.1 9.1 8 1 1 9 9 9 3 HEAT-like repeat HEAT PF02985.22 EAQ85470.1 - 7.2e-14 50.7 5.0 0.035 14.4 0.1 9.1 9 0 0 9 9 8 2 HEAT repeat HEAT_2 PF13646.6 EAQ85470.1 - 1.8e-12 47.4 18.0 0.07 13.5 0.2 9.0 6 3 2 8 8 8 4 HEAT repeats Cnd1 PF12717.7 EAQ85470.1 - 6e-08 32.9 1.2 0.00092 19.3 0.0 4.2 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 EAQ85470.1 - 5.5e-06 26.9 0.4 1.3 9.6 0.0 5.1 6 0 0 6 6 5 2 Vacuolar 14 Fab1-binding region Arm PF00514.23 EAQ85470.1 - 1.8e-05 24.6 1.8 39 4.5 0.0 7.5 7 0 0 7 7 7 0 Armadillo/beta-catenin-like repeat CLASP_N PF12348.8 EAQ85470.1 - 8.6e-05 22.2 0.1 0.0056 16.3 0.0 3.4 4 0 0 4 4 4 1 CLASP N terminal IBN_N PF03810.19 EAQ85470.1 - 0.00018 21.4 1.4 0.0081 16.1 0.3 3.0 3 0 0 3 3 3 1 Importin-beta N-terminal domain DRIM PF07539.12 EAQ85470.1 - 0.011 14.0 0.3 14 3.8 0.1 4.2 5 0 0 5 5 5 0 Down-regulated in metastasis IFRD PF05004.13 EAQ85470.1 - 0.015 14.4 1.5 3.2 6.8 0.0 3.9 2 1 2 4 4 4 0 Interferon-related developmental regulator (IFRD) RTP1_C1 PF10363.9 EAQ85470.1 - 0.017 15.3 0.2 5.2 7.3 0.0 4.3 4 0 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 Importin_rep_4 PF18808.1 EAQ85470.1 - 0.15 12.4 11.6 5.4 7.4 0.1 4.9 5 0 0 5 5 4 0 Importin repeat MMS19_C PF12460.8 EAQ85470.1 - 0.26 10.4 2.2 1.4 7.9 0.1 3.0 3 0 0 3 3 3 0 RNAPII transcription regulator C-terminal Cerato-platanin PF07249.12 EAQ85471.1 - 4.6e-06 26.7 0.5 4.6e-06 26.7 0.5 1.9 2 0 0 2 2 2 1 Cerato-platanin NUDIX PF00293.28 EAQ85472.1 - 4.5e-14 52.6 0.9 6.3e-14 52.1 0.9 1.3 1 0 0 1 1 1 1 NUDIX domain tRNA-synt_1d PF00750.19 EAQ85473.1 - 1.8e-43 148.8 0.9 4.2e-22 78.6 0.2 2.2 1 1 1 2 2 2 2 tRNA synthetases class I (R) RVT_1 PF00078.27 EAQ85473.1 - 5e-16 58.9 0.0 7.2e-16 58.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DALR_1 PF05746.15 EAQ85473.1 - 8.9e-10 38.8 0.0 1.6e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 DALR anticodon binding domain DUF1996 PF09362.10 EAQ85474.1 - 3.8e-42 144.9 0.0 4.8e-42 144.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) PIF1 PF05970.14 EAQ85475.1 - 1.1e-18 67.5 0.1 2.1e-18 66.7 0.1 1.3 1 0 0 1 1 1 1 PIF1-like helicase Dimer_Tnp_hAT PF05699.14 EAQ85475.1 - 1.1e-17 63.6 0.7 4.2e-17 61.7 0.2 2.1 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region AAA_30 PF13604.6 EAQ85475.1 - 6.8e-07 29.2 0.0 1.9e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAQ85475.1 - 0.0034 17.7 0.0 0.0079 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 EAQ85475.1 - 0.024 14.5 0.0 0.076 12.9 0.0 1.9 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Ank PF00023.30 EAQ85477.1 - 1.4e-15 56.9 0.3 2.9e-06 27.5 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.7 EAQ85477.1 - 2.1e-11 44.2 0.1 9.1e-11 42.2 0.1 2.1 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAQ85477.1 - 9e-11 42.1 0.3 7.7e-06 26.4 0.1 3.4 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAQ85477.1 - 3.4e-10 40.0 0.2 1.2e-09 38.2 0.1 2.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAQ85477.1 - 6.7e-10 38.4 0.1 1.7e-05 24.8 0.0 4.5 4 1 0 4 4 4 1 Ankyrin repeat Abhydrolase_3 PF07859.13 EAQ85480.1 - 2.7e-41 141.8 0.0 3.6e-41 141.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 EAQ85480.1 - 3.7e-05 22.8 0.0 5.3e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Esterase PF00756.20 EAQ85480.1 - 0.11 12.1 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Putative esterase tRNA-synt_2 PF00152.20 EAQ85481.1 - 8.9e-73 245.1 0.0 1.4e-72 244.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.9 EAQ85481.1 - 1.2e-23 83.6 0.0 1.9e-23 83.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2156) tRNA_anti-codon PF01336.25 EAQ85481.1 - 1e-05 25.4 0.0 2.1e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EAQ85481.1 - 0.00055 19.5 0.1 0.83 9.1 0.1 2.5 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) DUF945 PF06097.11 EAQ85482.1 - 0.13 11.3 1.4 0.19 10.8 1.4 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF945) PAN_1 PF00024.26 EAQ85482.1 - 0.14 12.2 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 PAN domain B277 PF17623.2 EAQ85482.1 - 0.55 9.3 3.7 0.79 8.8 3.7 1.2 1 0 0 1 1 1 0 Domain of unknown function Dmrt1 PF12374.8 EAQ85482.1 - 2.8 8.4 5.2 0.5 10.9 0.6 2.1 2 0 0 2 2 2 0 Double-sex mab3 related transcription factor 1 GMC_oxred_N PF00732.19 EAQ85483.1 - 3.3e-51 174.4 0.0 4e-50 170.9 0.0 2.0 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EAQ85483.1 - 3.1e-31 108.8 0.0 5.7e-31 108.0 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 EAQ85483.1 - 6.8e-07 28.7 1.5 0.00081 18.6 0.1 2.5 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.6 EAQ85483.1 - 0.00064 19.1 1.2 0.015 14.6 0.3 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EAQ85483.1 - 0.00084 19.0 1.3 0.012 15.3 0.3 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EAQ85483.1 - 0.0011 18.3 0.4 0.008 15.4 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EAQ85483.1 - 0.0012 17.7 0.0 0.16 10.7 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_8 PF13450.6 EAQ85483.1 - 0.0023 18.1 0.9 0.0052 17.0 0.2 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 EAQ85483.1 - 0.0052 16.1 0.0 0.012 14.8 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain PALP PF00291.25 EAQ85483.1 - 0.011 15.2 0.8 0.1 12.0 0.0 2.7 3 0 0 3 3 3 0 Pyridoxal-phosphate dependent enzyme Lycopene_cycl PF05834.12 EAQ85483.1 - 0.015 14.4 0.0 0.025 13.6 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein TrkA_N PF02254.18 EAQ85483.1 - 0.022 15.0 0.2 0.047 13.9 0.2 1.5 1 0 0 1 1 1 0 TrkA-N domain Thi4 PF01946.17 EAQ85483.1 - 0.075 12.3 0.1 0.16 11.2 0.1 1.5 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.14 EAQ85483.1 - 0.14 11.0 0.1 0.26 10.1 0.1 1.4 1 0 0 1 1 1 0 Tryptophan halogenase zf-RVT PF13966.6 EAQ85484.1 - 0.08 13.7 0.0 0.22 12.2 0.0 1.7 2 0 0 2 2 2 0 zinc-binding in reverse transcriptase Sugar_tr PF00083.24 EAQ85487.1 - 2.6e-33 115.6 21.8 5.7e-21 74.9 4.8 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EAQ85487.1 - 1e-17 64.1 30.8 1.2e-10 40.8 20.2 2.4 2 0 0 2 2 2 2 Major Facilitator Superfamily CC190 PF15768.5 EAQ85488.1 - 0.012 15.7 2.2 0.024 14.7 2.2 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 190 FUSC PF04632.12 EAQ85488.1 - 0.31 9.5 2.2 0.44 9.0 2.2 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF1101 PF06503.11 EAQ85489.1 - 0.03 13.6 0.5 0.046 13.0 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1101) Methyltransf_2 PF00891.18 EAQ85490.1 - 2.3e-20 72.8 0.0 3.5e-20 72.2 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain MarR_2 PF12802.7 EAQ85490.1 - 0.028 14.3 0.0 0.074 13.0 0.0 1.7 1 0 0 1 1 1 0 MarR family NSP11 PF06471.12 EAQ85490.1 - 0.14 10.6 0.0 0.19 10.1 0.0 1.1 1 0 0 1 1 1 0 NSP11 Ank_2 PF12796.7 EAQ85492.1 - 2.4e-09 37.6 0.0 0.0043 17.6 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAQ85492.1 - 1.1e-08 35.1 0.5 0.0076 16.5 0.0 3.8 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAQ85492.1 - 8.1e-08 32.7 0.2 0.0059 17.2 0.0 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAQ85492.1 - 3.4e-07 30.1 0.9 0.14 12.8 0.1 4.7 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 EAQ85492.1 - 3.3e-06 27.3 5.9 0.048 14.1 0.2 5.2 5 0 0 5 5 5 2 Ankyrin repeat F-box_4 PF15966.5 EAQ85492.1 - 0.00084 19.2 0.4 0.0018 18.1 0.0 1.7 2 0 0 2 2 2 1 F-box F-box-like PF12937.7 EAQ85492.1 - 0.0033 17.3 2.0 0.0034 17.2 0.1 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EAQ85492.1 - 0.0098 15.8 0.2 0.023 14.6 0.2 1.6 1 0 0 1 1 1 1 F-box domain Abhydrolase_6 PF12697.7 EAQ85493.1 - 1.2e-15 58.8 0.1 1.4e-15 58.5 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EAQ85493.1 - 0.05 12.9 0.1 0.19 11.0 0.0 2.0 3 0 0 3 3 3 0 Serine aminopeptidase, S33 PGAP1 PF07819.13 EAQ85493.1 - 0.058 13.1 0.0 0.097 12.4 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Lipase_3 PF01764.25 EAQ85493.1 - 0.088 12.7 0.1 0.18 11.7 0.1 1.5 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_3 PF07859.13 EAQ85493.1 - 0.11 12.4 0.1 0.14 12.0 0.1 1.3 1 1 0 1 1 1 0 alpha/beta hydrolase fold DNA_pol3_a_NI PF14480.6 EAQ85494.1 - 0.011 15.7 0.0 0.027 14.5 0.0 1.6 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus I LUC7 PF03194.15 EAQ85494.1 - 0.012 15.3 3.0 0.012 15.3 3.0 1.9 2 0 0 2 2 2 0 LUC7 N_terminus Sec2p PF06428.11 EAQ85494.1 - 0.43 10.6 6.7 0.12 12.3 2.3 2.3 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p MerR-DNA-bind PF09278.11 EAQ85494.1 - 1.4 9.5 12.0 1.9 9.0 2.5 3.5 3 1 0 3 3 3 0 MerR, DNA binding SlyX PF04102.12 EAQ85495.1 - 0.034 14.7 6.4 0.097 13.3 5.7 2.1 1 1 0 1 1 1 0 SlyX DUF948 PF06103.11 EAQ85495.1 - 0.061 13.6 1.3 0.13 12.6 1.3 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Herpes_UL6 PF01763.16 EAQ85495.1 - 0.067 11.7 0.5 0.11 11.0 0.5 1.2 1 0 0 1 1 1 0 Herpesvirus UL6 like Phage_lysis PF03245.13 EAQ85495.1 - 0.097 12.8 2.9 0.29 11.3 2.9 1.8 1 0 0 1 1 1 0 Bacteriophage Rz lysis protein Spc7 PF08317.11 EAQ85495.1 - 0.57 9.0 5.3 1 8.2 5.3 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein TMPIT PF07851.13 EAQ85495.1 - 0.71 9.1 3.3 1.2 8.3 3.3 1.2 1 0 0 1 1 1 0 TMPIT-like protein Apolipoprotein PF01442.18 EAQ85495.1 - 5.7 6.8 10.8 0.22 11.3 4.8 1.7 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain ADIP PF11559.8 EAQ85495.1 - 5.7 7.0 12.8 0.17 11.9 6.4 1.7 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Pkinase PF00069.25 EAQ85497.1 - 1.6e-45 155.6 0.0 1.3e-44 152.6 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ85497.1 - 1.1e-17 64.1 0.0 2.8e-17 62.9 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 EAQ85497.1 - 1.8e-10 41.0 0.3 3.9e-10 39.9 0.3 1.6 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EAQ85497.1 - 0.0027 18.0 0.0 0.0057 16.9 0.0 1.5 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain SAICAR_synt PF01259.18 EAQ85498.1 - 1.5e-32 113.2 0.0 1.3e-30 106.9 0.0 2.2 1 1 0 1 1 1 1 SAICAR synthetase 2-Hacid_dh_C PF02826.19 EAQ85499.1 - 1.4e-44 151.6 0.0 1.8e-44 151.2 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EAQ85499.1 - 0.0014 18.3 0.0 0.0044 16.7 0.0 1.8 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain MULE PF10551.9 EAQ85500.1 - 1.3e-27 96.0 0.0 3e-27 94.9 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain PIF1 PF05970.14 EAQ85501.1 - 9.1e-19 67.8 0.0 1.6e-18 67.1 0.0 1.3 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 EAQ85501.1 - 1.6e-07 31.2 0.1 5.8e-07 29.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EAQ85501.1 - 0.00097 19.5 0.0 0.0023 18.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 EAQ85501.1 - 0.011 15.5 0.0 0.033 14.0 0.0 1.9 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain UvrD_C_2 PF13538.6 EAQ85502.1 - 0.0049 16.7 0.0 0.023 14.5 0.0 2.2 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain PIF1 PF05970.14 EAQ85502.1 - 0.11 11.7 0.1 0.19 10.9 0.1 1.3 1 0 0 1 1 1 0 PIF1-like helicase CN_hydrolase PF00795.22 EAQ85504.1 - 2.7e-38 131.8 0.4 3.2e-38 131.6 0.4 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase PAF-AH_p_II PF03403.13 EAQ85505.1 - 7.6e-22 77.3 0.0 2.5e-10 39.4 0.0 2.1 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Hydrolase_4 PF12146.8 EAQ85505.1 - 2.6e-07 30.2 0.0 0.0078 15.5 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EAQ85505.1 - 2.5e-05 25.0 0.6 3.8e-05 24.4 0.6 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 EAQ85505.1 - 0.00022 20.2 0.0 0.00042 19.3 0.0 1.4 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_5 PF12695.7 EAQ85505.1 - 0.00038 20.3 0.1 0.14 12.0 0.0 2.4 2 0 0 2 2 2 2 Alpha/beta hydrolase family PGAP1 PF07819.13 EAQ85505.1 - 0.0055 16.5 0.0 0.0091 15.7 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_3 PF07859.13 EAQ85505.1 - 0.0065 16.3 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EAQ85505.1 - 0.0074 15.8 0.2 0.037 13.5 0.1 2.1 2 1 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 EAQ85505.1 - 0.033 13.8 0.0 0.19 11.3 0.0 1.9 2 0 0 2 2 2 0 alpha/beta hydrolase fold MFS_1 PF07690.16 EAQ85506.1 - 5.5e-19 68.3 41.8 5.5e-19 68.3 41.8 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 EAQ85506.1 - 0.026 12.8 8.1 0.11 10.8 2.5 2.2 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DoxD PF04173.13 EAQ85506.1 - 0.096 12.6 3.8 0.54 10.2 3.8 2.2 1 1 0 1 1 1 0 TQO small subunit DoxD Epimerase PF01370.21 EAQ85507.1 - 6.7e-20 71.6 0.0 1.1e-19 70.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EAQ85507.1 - 4.7e-12 46.0 0.3 1.5e-11 44.3 0.3 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EAQ85507.1 - 4.3e-11 42.3 0.0 6e-11 41.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EAQ85507.1 - 2.1e-08 33.7 0.1 6.4e-07 28.8 0.0 2.1 1 1 1 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.6 EAQ85507.1 - 2.5e-08 34.1 0.7 5.7e-08 32.9 0.5 1.7 2 0 0 2 2 2 1 NAD(P)H-binding adh_short PF00106.25 EAQ85507.1 - 2.7e-06 27.0 1.6 0.00095 18.7 0.3 2.3 2 0 0 2 2 2 2 short chain dehydrogenase NmrA PF05368.13 EAQ85507.1 - 9.6e-05 22.0 0.6 0.00027 20.6 0.5 1.8 2 1 0 2 2 2 1 NmrA-like family KR PF08659.10 EAQ85507.1 - 0.0011 18.9 0.4 0.03 14.2 0.4 2.4 1 1 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 EAQ85507.1 - 0.0053 15.9 0.2 3.5 6.6 0.0 3.1 3 0 0 3 3 3 2 RmlD substrate binding domain FAD_binding_4 PF01565.23 EAQ85508.1 - 3.1e-16 59.4 0.0 4.8e-16 58.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain GFO_IDH_MocA PF01408.22 EAQ85509.1 - 3.2e-14 53.8 0.0 5.3e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 EAQ85509.1 - 0.00077 20.1 0.1 0.0015 19.2 0.1 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain MFS_1 PF07690.16 EAQ85512.1 - 4.7e-07 29.1 26.1 4.7e-07 29.1 26.1 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Asp PF00026.23 EAQ85513.1 - 2.7e-21 76.3 0.0 8.6e-17 61.5 0.0 2.0 2 0 0 2 2 2 2 Eukaryotic aspartyl protease Asp_protease_2 PF13650.6 EAQ85513.1 - 1.5e-06 28.8 0.0 1.2 9.8 0.0 3.3 3 0 0 3 3 3 3 Aspartyl protease gag-asp_proteas PF13975.6 EAQ85513.1 - 0.0016 18.9 0.0 4.1 8.0 0.0 3.2 3 0 0 3 3 3 1 gag-polyprotein putative aspartyl protease TAXi_N PF14543.6 EAQ85513.1 - 0.017 15.4 0.4 0.12 12.6 0.4 2.3 1 1 0 1 1 1 0 Xylanase inhibitor N-terminal p450 PF00067.22 EAQ85514.1 - 5.7e-67 226.4 0.0 7.3e-67 226.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Sugar_tr PF00083.24 EAQ85515.1 - 8.1e-60 203.0 11.5 5.2e-48 164.0 4.5 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EAQ85515.1 - 7.3e-09 35.0 25.6 9.7e-07 28.0 28.6 2.3 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EAQ85515.1 - 0.00094 17.7 1.1 0.0013 17.2 1.1 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) p450 PF00067.22 EAQ85516.1 - 0.13 11.0 0.0 0.14 10.9 0.0 1.0 1 0 0 1 1 1 0 Cytochrome P450 FAD_binding_3 PF01494.19 EAQ85517.1 - 3.9e-09 36.2 0.4 1.8e-08 34.0 0.4 1.8 1 1 0 1 1 1 1 FAD binding domain Aldedh PF00171.22 EAQ85518.1 - 4.8e-156 519.9 0.7 5.5e-156 519.7 0.7 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 EAQ85518.1 - 0.015 14.7 0.0 1.1 8.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) Amidohydro_2 PF04909.14 EAQ85519.1 - 3.6e-29 102.5 0.1 5.6e-29 101.8 0.1 1.2 1 0 0 1 1 1 1 Amidohydrolase DUF3439 PF11921.8 EAQ85519.1 - 1 9.3 6.9 2 8.4 6.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) AzlC PF03591.14 EAQ85520.1 - 0.002 18.6 0.4 0.0032 17.9 0.4 1.4 1 0 0 1 1 1 1 AzlC protein DUF4106 PF13388.6 EAQ85521.1 - 0.57 9.4 5.1 0.59 9.3 5.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) DLH PF01738.18 EAQ85522.1 - 6.8e-31 107.5 0.1 8.1e-31 107.3 0.1 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family DUF915 PF06028.11 EAQ85522.1 - 0.12 11.7 0.0 0.72 9.1 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) DUF747 PF05346.11 EAQ85523.1 - 3.7e-123 411.1 1.0 5e-123 410.6 1.0 1.2 1 0 0 1 1 1 1 Eukaryotic membrane protein family WW PF00397.26 EAQ85524.1 - 8.5e-10 38.6 4.5 3.3e-09 36.7 4.5 2.1 1 0 0 1 1 1 1 WW domain FF PF01846.19 EAQ85524.1 - 3.7e-08 33.4 1.1 9.5e-08 32.1 0.2 2.3 2 0 0 2 2 2 1 FF domain PIF1 PF05970.14 EAQ85524.1 - 0.00032 20.0 0.0 0.00048 19.4 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase K_channel_TID PF07941.11 EAQ85525.1 - 0.042 14.3 1.4 0.054 14.0 1.4 1.1 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain zf-RVT PF13966.6 EAQ85526.1 - 0.11 13.2 0.0 0.23 12.2 0.0 1.5 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase SSP160 PF06933.11 EAQ85527.1 - 0.012 13.8 7.8 0.016 13.5 7.8 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 tRNA_anti-like PF12869.7 EAQ85527.1 - 0.17 11.5 0.1 0.27 10.9 0.1 1.2 1 0 0 1 1 1 0 tRNA_anti-like Pilin_N PF07790.11 EAQ85527.1 - 0.2 12.6 5.1 16 6.5 5.1 2.4 1 1 0 1 1 1 0 Archaeal Type IV pilin, N-terminal Alpha_GJ PF03229.13 EAQ85527.1 - 1.3 9.6 10.2 2.1 8.9 10.2 1.3 1 0 0 1 1 1 0 Alphavirus glycoprotein J DUF2749 PF10907.8 EAQ85527.1 - 6.2 7.1 8.6 15 5.8 8.2 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2749) K_oxygenase PF13434.6 EAQ85528.1 - 1e-50 172.8 0.0 6.2e-33 114.4 0.0 2.1 1 1 1 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) GBP_PSP PF02425.15 EAQ85528.1 - 0.17 11.5 0.1 0.45 10.2 0.1 1.7 1 0 0 1 1 1 0 Paralytic/GBP/PSP peptide AMP-binding PF00501.28 EAQ85529.1 - 6.8e-232 769.5 0.0 5.8e-81 272.2 0.0 3.4 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.20 EAQ85529.1 - 1.3e-161 538.3 0.0 2.2e-33 115.7 0.0 6.9 6 1 0 6 6 6 6 Condensation domain PP-binding PF00550.25 EAQ85529.1 - 5.1e-48 161.3 15.9 2.7e-09 37.2 0.5 6.8 6 0 0 6 6 6 6 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EAQ85529.1 - 1.5e-09 38.7 0.0 0.089 13.8 0.0 3.8 3 0 0 3 3 3 3 AMP-binding enzyme C-terminal domain Transferase PF02458.15 EAQ85529.1 - 0.012 14.2 0.3 0.6 8.7 0.0 3.3 4 0 0 4 4 4 0 Transferase family Mur_ligase PF01225.25 EAQ85529.1 - 0.024 15.0 0.1 0.98 9.8 0.0 3.0 3 0 0 3 3 3 0 Mur ligase family, catalytic domain SH3_1 PF00018.28 EAQ85530.1 - 6.8e-05 22.4 0.0 0.00013 21.5 0.0 1.5 1 0 0 1 1 1 1 SH3 domain zf-C2H2_4 PF13894.6 EAQ85530.1 - 0.014 16.2 5.6 1.4 9.9 0.2 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger SH3_2 PF07653.17 EAQ85530.1 - 0.016 14.9 0.0 0.037 13.7 0.0 1.7 1 0 0 1 1 1 0 Variant SH3 domain zf-C2H2 PF00096.26 EAQ85530.1 - 0.044 14.2 0.9 0.044 14.2 0.9 2.9 3 0 0 3 3 3 0 Zinc finger, C2H2 type Rad50_zn_hook PF04423.14 EAQ85530.1 - 0.075 12.9 0.3 1.5 8.7 0.0 2.5 2 0 0 2 2 2 0 Rad50 zinc hook motif DUF1264 PF06884.11 EAQ85531.1 - 6.7e-75 250.4 0.0 7.9e-75 250.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1264) NCD1 PF04904.13 EAQ85532.1 - 0.14 12.2 0.3 2.4 8.2 0.0 2.9 3 0 0 3 3 3 0 NAB conserved region 1 (NCD1) DUF4813 PF16072.5 EAQ85532.1 - 0.22 11.1 5.8 0.33 10.6 5.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) HpcH_HpaI PF03328.14 EAQ85534.1 - 5.5e-17 61.6 0.0 2.6e-16 59.4 0.0 1.9 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PK PF00224.21 EAQ85534.1 - 0.021 13.7 0.0 0.04 12.8 0.0 1.5 2 0 0 2 2 2 0 Pyruvate kinase, barrel domain VIT1 PF01988.19 EAQ85535.1 - 0.00057 19.8 0.1 0.00085 19.2 0.1 1.2 1 0 0 1 1 1 1 VIT family EHN PF06441.12 EAQ85536.1 - 3.8e-36 123.7 0.1 3.8e-36 123.7 0.1 1.9 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 EAQ85536.1 - 6.6e-14 52.2 0.0 1.1e-13 51.4 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EAQ85536.1 - 0.013 16.1 9.1 0.098 13.2 9.1 2.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family Glyco_hydro_16 PF00722.21 EAQ85537.1 - 1.2e-12 47.6 1.6 2.3e-12 46.8 1.6 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 CBM_1 PF00734.18 EAQ85537.1 - 2.8e-08 33.6 13.0 2.8e-08 33.6 13.0 2.2 2 0 0 2 2 2 1 Fungal cellulose binding domain cIII PF08134.11 EAQ85538.1 - 0.044 13.5 0.2 0.094 12.5 0.2 1.5 1 0 0 1 1 1 0 cIII protein family YL1 PF05764.13 EAQ85538.1 - 4.9 7.2 12.1 8.4 6.4 12.1 1.3 1 0 0 1 1 1 0 YL1 nuclear protein Pes-10 PF07149.11 EAQ85538.1 - 8.5 5.3 6.8 11 4.9 6.8 1.1 1 0 0 1 1 1 0 Pes-10 AAA PF00004.29 EAQ85541.1 - 3e-15 56.8 0.0 1.3e-14 54.8 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EAQ85541.1 - 0.00027 21.3 0.0 0.0006 20.2 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 EAQ85541.1 - 0.0076 16.3 0.0 0.016 15.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EAQ85541.1 - 0.0087 16.3 0.0 0.026 14.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EAQ85541.1 - 0.076 13.2 0.0 0.17 12.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EAQ85541.1 - 0.12 12.0 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain Zot PF05707.12 EAQ85541.1 - 0.13 11.9 0.0 0.82 9.3 0.0 2.0 1 1 0 2 2 2 0 Zonular occludens toxin (Zot) RuvB_N PF05496.12 EAQ85541.1 - 0.16 11.7 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_11 PF13086.6 EAQ85541.1 - 0.19 11.5 0.0 0.36 10.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain Helitron_like_N PF14214.6 EAQ85542.1 - 3.2e-19 69.9 0.0 6e-19 69.0 0.0 1.4 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.14 EAQ85542.1 - 2e-08 33.8 0.0 0.0031 16.7 0.1 2.3 1 1 1 2 2 2 2 PIF1-like helicase UvrD_C_2 PF13538.6 EAQ85542.1 - 0.00034 20.4 0.0 0.00078 19.2 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.14 EAQ85542.1 - 0.0017 16.4 0.0 0.0025 15.8 0.0 1.1 1 0 0 1 1 1 1 Helicase ASCH PF04266.14 EAQ85543.1 - 8.5e-11 42.4 0.0 1.1e-10 42.0 0.0 1.1 1 0 0 1 1 1 1 ASCH domain zf-LITAF-like PF10601.9 EAQ85544.1 - 2.7e-15 56.4 14.9 3.5e-15 56.0 14.9 1.2 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain Cys_rich_KTR PF14205.6 EAQ85544.1 - 0.00062 19.5 1.0 0.02 14.7 0.1 2.3 2 0 0 2 2 2 1 Cysteine-rich KTR Ribosomal_L37ae PF01780.19 EAQ85544.1 - 0.068 13.3 0.5 2.2 8.4 0.0 2.4 2 0 0 2 2 2 0 Ribosomal L37ae protein family NOB1_Zn_bind PF08772.11 EAQ85544.1 - 0.069 13.3 10.4 6 7.1 8.2 2.2 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like IF-2B PF01008.17 EAQ85547.1 - 1.2e-14 54.2 0.0 2.1e-14 53.4 0.0 1.4 1 1 0 1 1 1 1 Initiation factor 2 subunit family NUDIX PF00293.28 EAQ85547.1 - 1.3e-12 47.9 0.3 6.1e-11 42.5 0.0 2.5 3 0 0 3 3 3 1 NUDIX domain Fungal_trans PF04082.18 EAQ85548.1 - 1.8e-09 37.0 0.0 3.9e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EAQ85548.1 - 8.1e-06 25.9 9.8 1.8e-05 24.8 9.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Nucleotid_trans PF03407.16 EAQ85549.1 - 7.2e-08 32.7 0.0 1e-07 32.2 0.0 1.2 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Glyco_transf_34 PF05637.12 EAQ85549.1 - 0.043 13.5 0.4 0.062 13.0 0.4 1.2 1 0 0 1 1 1 0 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.14 EAQ85549.1 - 0.16 11.5 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF273 Lactamase_B_2 PF12706.7 EAQ85550.1 - 0.00015 21.4 0.0 0.00032 20.3 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EAQ85550.1 - 0.0024 17.9 8.3 0.0045 17.0 0.4 2.6 2 1 0 2 2 2 2 Metallo-beta-lactamase superfamily Exo_endo_phos_2 PF14529.6 EAQ85551.1 - 1e-10 41.5 0.0 2.5e-10 40.2 0.0 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RVT_1 PF00078.27 EAQ85551.1 - 1.1e-06 28.4 0.0 2e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 EAQ85551.1 - 0.00017 21.5 3.7 0.00035 20.5 3.7 1.6 1 0 0 1 1 1 1 Zinc knuckle RVT_3 PF13456.6 EAQ85551.1 - 0.00033 20.5 0.0 0.0028 17.5 0.0 2.4 2 0 0 2 2 2 1 Reverse transcriptase-like GCSF PF16647.5 EAQ85551.1 - 0.083 12.7 0.1 0.21 11.4 0.1 1.7 1 0 0 1 1 1 0 Granulocyte colony-stimulating factor PurS PF02700.14 EAQ85551.1 - 0.15 12.2 0.0 0.62 10.3 0.0 2.1 1 0 0 1 1 1 0 Phosphoribosylformylglycinamidine (FGAM) synthase zf-CCHC_3 PF13917.6 EAQ85551.1 - 0.89 9.6 5.8 1 9.4 3.2 2.3 2 0 0 2 2 2 0 Zinc knuckle PIF1 PF05970.14 EAQ85553.1 - 3e-07 29.9 0.0 0.00013 21.3 0.0 2.2 2 0 0 2 2 2 2 PIF1-like helicase UvrD_C_2 PF13538.6 EAQ85553.1 - 0.022 14.6 0.0 0.13 12.1 0.0 2.2 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.14 EAQ85553.1 - 0.027 12.4 0.0 0.037 12.0 0.0 1.1 1 0 0 1 1 1 0 Helicase PAN_4 PF14295.6 EAQ85555.1 - 0.0001 22.1 0.2 0.00019 21.3 0.2 1.4 1 0 0 1 1 1 1 PAN domain Sh_2 PF17512.2 EAQ85555.1 - 0.0067 16.2 2.9 0.013 15.3 2.9 1.6 1 1 0 1 1 1 1 Metapneumovirus Small hydrophobic protein PAN_3 PF08277.12 EAQ85555.1 - 0.059 13.2 0.1 0.12 12.2 0.1 1.5 1 0 0 1 1 1 0 PAN-like domain DUF4342 PF14242.6 EAQ85555.1 - 2 8.5 3.8 4.7 7.3 3.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4342) Sugar_tr PF00083.24 EAQ85556.1 - 2.3e-57 194.8 1.8 2.9e-57 194.5 1.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EAQ85556.1 - 3.3e-22 78.9 3.8 3.9e-22 78.7 3.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 EAQ85556.1 - 0.00038 19.1 2.3 0.0024 16.5 1.4 2.2 2 0 0 2 2 2 1 MFS/sugar transport protein TRI12 PF06609.13 EAQ85556.1 - 0.00093 17.7 0.7 0.0014 17.2 0.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) PTR2 PF00854.21 EAQ85556.1 - 0.011 14.6 1.9 0.017 14.0 1.5 1.4 1 1 0 1 1 1 0 POT family OATP PF03137.20 EAQ85556.1 - 0.19 10.0 8.2 0.088 11.1 0.5 2.1 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF4188 PF13826.6 EAQ85557.1 - 2.7e-35 121.3 0.0 4e-35 120.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4188) Dehydratase_hem PF13816.6 EAQ85557.1 - 0.0091 15.4 0.1 0.33 10.3 0.0 2.0 1 1 1 2 2 2 2 Haem-containing dehydratase DUF3721 PF12518.8 EAQ85557.1 - 0.17 11.8 0.3 6.9 6.6 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function Dimer_Tnp_hAT PF05699.14 EAQ85558.1 - 8.5e-20 70.3 0.2 1.3e-19 69.8 0.2 1.3 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DDE_1 PF03184.19 EAQ85559.1 - 1.6e-27 96.3 0.0 2.7e-27 95.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.16 EAQ85559.1 - 9.6e-09 34.9 0.0 2.6e-08 33.4 0.0 1.7 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.16 EAQ85559.1 - 6.1e-07 29.4 0.1 4.5e-06 26.6 0.0 2.2 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.6 EAQ85559.1 - 5.3e-05 23.0 0.1 0.018 14.8 0.0 3.1 3 0 0 3 3 3 1 DDE superfamily endonuclease SpoIIID PF12116.8 EAQ85559.1 - 0.05 13.7 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Stage III sporulation protein D ZapB PF06005.12 EAQ85559.1 - 0.13 12.7 1.3 0.64 10.5 1.0 2.4 2 0 0 2 2 2 0 Cell division protein ZapB OmpH PF03938.14 EAQ85560.1 - 0.00055 20.3 1.8 0.001 19.4 1.8 1.5 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) SseC PF04888.12 EAQ85560.1 - 0.00057 19.6 1.5 0.00081 19.1 1.5 1.2 1 0 0 1 1 1 1 Secretion system effector C (SseC) like family DUF2992 PF11208.8 EAQ85560.1 - 0.00074 19.8 1.2 0.0011 19.2 1.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2992) Cnn_1N PF07989.11 EAQ85560.1 - 0.0051 16.9 2.7 0.01 16.0 2.7 1.5 1 0 0 1 1 1 1 Centrosomin N-terminal motif 1 WXG100 PF06013.12 EAQ85560.1 - 0.0053 17.0 1.5 0.0098 16.1 0.4 1.9 2 0 0 2 2 2 1 Proteins of 100 residues with WXG DLP_helical PF18709.1 EAQ85560.1 - 0.0063 15.8 1.6 0.0087 15.3 1.6 1.2 1 0 0 1 1 1 1 Dynamin-like helical domain Laminin_II PF06009.12 EAQ85560.1 - 0.0065 16.5 1.4 0.64 10.0 0.4 2.2 2 0 0 2 2 2 1 Laminin Domain II KfrA_N PF11740.8 EAQ85560.1 - 0.013 16.1 4.9 0.013 16.1 4.9 2.0 2 1 0 2 2 1 0 Plasmid replication region DNA-binding N-term Erythro_esteras PF05139.14 EAQ85560.1 - 0.014 15.3 0.5 0.019 14.8 0.5 1.2 1 0 0 1 1 1 0 Erythromycin esterase DUF4407 PF14362.6 EAQ85560.1 - 0.015 14.7 0.5 0.018 14.4 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) COG2 PF06148.11 EAQ85560.1 - 0.023 14.8 0.8 0.042 13.9 0.8 1.4 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 DinB_2 PF12867.7 EAQ85560.1 - 0.03 14.8 0.1 0.047 14.2 0.1 1.4 1 0 0 1 1 1 0 DinB superfamily Rx_N PF18052.1 EAQ85560.1 - 0.032 14.5 1.2 0.055 13.7 0.7 1.7 2 0 0 2 2 1 0 Rx N-terminal domain YPEB PF14620.6 EAQ85560.1 - 0.033 13.5 0.1 0.04 13.3 0.1 1.1 1 0 0 1 1 1 0 YpeB sporulation MycE_N PF17843.1 EAQ85560.1 - 0.042 14.3 2.8 0.081 13.4 2.8 1.5 1 0 0 1 1 1 0 MycE methyltransferase N-terminal Rogdi_lz PF10259.9 EAQ85560.1 - 0.044 13.2 0.1 0.079 12.4 0.1 1.5 1 1 0 1 1 1 0 Rogdi leucine zipper containing protein GCIP PF13324.6 EAQ85560.1 - 0.061 12.9 0.1 0.073 12.7 0.1 1.3 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting DUF948 PF06103.11 EAQ85560.1 - 0.072 13.3 0.2 0.19 12.0 0.2 1.7 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) THOC7 PF05615.13 EAQ85560.1 - 0.075 13.3 5.3 0.13 12.5 5.3 1.3 1 0 0 1 1 1 0 Tho complex subunit 7 GAS PF13851.6 EAQ85560.1 - 0.076 12.4 4.5 0.12 11.7 4.5 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Prominin PF05478.11 EAQ85560.1 - 0.24 9.3 0.1 0.3 9.0 0.1 1.1 1 0 0 1 1 1 0 Prominin EMC3_TMCO1 PF01956.16 EAQ85560.1 - 0.61 9.8 3.9 1.1 9.0 3.9 1.4 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like SAPIS-gp6 PF16722.5 EAQ85560.1 - 1.5 9.3 6.1 4.1 7.9 6.0 1.8 1 1 0 1 1 1 0 Pathogenicity island protein gp6 in Staphylococcus YbaB_DNA_bd PF02575.16 EAQ85560.1 - 1.8 8.9 11.8 4.1 7.7 6.8 3.3 3 1 1 4 4 4 0 YbaB/EbfC DNA-binding family tRNA-synt_1g PF09334.11 EAQ85561.1 - 9e-136 452.7 0.0 1.2e-134 448.9 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (M) Laminin_EGF PF00053.24 EAQ85561.1 - 0.18 12.0 2.4 0.42 10.8 2.4 1.7 1 0 0 1 1 1 0 Laminin EGF domain RTA1 PF04479.13 EAQ85562.1 - 1.2e-43 149.2 5.7 1.5e-43 148.8 5.7 1.2 1 0 0 1 1 1 1 RTA1 like protein HXXEE PF13787.6 EAQ85562.1 - 0.013 16.3 0.9 0.013 16.3 0.9 2.3 2 1 1 3 3 3 0 Protein of unknown function with HXXEE motif FAM199X PF15814.5 EAQ85562.1 - 3.2 6.7 4.4 4.5 6.3 4.4 1.1 1 0 0 1 1 1 0 Protein family FAM199X Lactonase PF10282.9 EAQ85563.1 - 5e-78 262.8 0.2 2e-65 221.4 0.0 2.0 1 1 1 2 2 2 2 Lactonase, 7-bladed beta-propeller TLP1_add_C PF18313.1 EAQ85563.1 - 0.1 12.6 0.1 0.35 10.8 0.1 1.9 2 0 0 2 2 2 0 Thiolase-like protein type 1 additional C-terminal domain PQQ PF01011.21 EAQ85563.1 - 0.11 12.5 0.3 6.6 6.8 0.2 3.4 3 0 0 3 3 3 0 PQQ enzyme repeat PepSY PF03413.19 EAQ85563.1 - 0.14 12.8 0.1 7.8 7.1 0.1 2.5 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain MoeA_N PF03453.17 EAQ85564.1 - 2e-35 121.9 0.4 3.8e-35 121.0 0.4 1.4 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoCF_biosynth PF00994.24 EAQ85564.1 - 1.6e-27 96.0 0.0 2.7e-27 95.2 0.0 1.4 1 0 0 1 1 1 1 Probable molybdopterin binding domain DMRL_synthase PF00885.19 EAQ85564.1 - 0.0011 18.9 0.0 0.002 17.9 0.0 1.3 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase Molybdopterin PF00384.22 EAQ85565.1 - 9e-66 222.6 0.0 1.3e-65 222.1 0.0 1.2 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Molybdop_Fe4S4 PF04879.16 EAQ85565.1 - 1.1e-10 41.3 0.7 2.6e-10 40.1 0.2 2.0 2 0 0 2 2 2 1 Molybdopterin oxidoreductase Fe4S4 domain OrsD PF12013.8 EAQ85565.1 - 1.3e-07 32.0 0.6 3.2e-07 30.8 0.0 2.0 2 0 0 2 2 2 1 Orsellinic acid/F9775 biosynthesis cluster protein D Molydop_binding PF01568.21 EAQ85565.1 - 5.9e-05 23.0 0.1 0.00038 20.5 0.0 2.2 1 1 1 2 2 2 1 Molydopterin dinucleotide binding domain OrsD PF12013.8 EAQ85566.1 - 2.1e-12 47.5 0.9 4.3e-12 46.5 0.9 1.6 1 0 0 1 1 1 1 Orsellinic acid/F9775 biosynthesis cluster protein D DEAD PF00270.29 EAQ85566.1 - 0.0011 18.7 0.0 0.0019 18.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Herpes_glycop PF01528.16 EAQ85566.1 - 0.044 12.6 0.1 0.083 11.7 0.1 1.4 1 0 0 1 1 1 0 Herpesvirus glycoprotein M Pribosyltran PF00156.27 EAQ85568.1 - 9.5e-24 83.7 0.0 2.3e-23 82.5 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosyl transferase domain P-mevalo_kinase PF04275.14 EAQ85568.1 - 1e-20 73.8 0.0 2.4e-20 72.6 0.0 1.7 1 0 0 1 1 1 1 Phosphomevalonate kinase FAD_binding_4 PF01565.23 EAQ85568.1 - 2.4e-15 56.5 4.8 4.8e-15 55.5 4.8 1.6 1 0 0 1 1 1 1 FAD binding domain UPRTase PF14681.6 EAQ85568.1 - 5e-05 22.8 0.0 0.00011 21.7 0.0 1.5 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.6 EAQ85568.1 - 0.0081 15.7 0.0 0.017 14.6 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase BBE PF08031.12 EAQ85568.1 - 0.027 14.6 0.0 0.078 13.1 0.0 1.7 1 0 0 1 1 1 0 Berberine and berberine like Methyltransf_23 PF13489.6 EAQ85568.1 - 0.035 13.9 0.0 0.12 12.2 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain TRAPPC10 PF12584.8 EAQ85568.1 - 0.099 12.3 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Trafficking protein particle complex subunit 10, TRAPPC10 GTP_cyclohydroI PF01227.22 EAQ85569.1 - 3.8e-60 202.4 1.1 4.7e-60 202.1 1.1 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 EAQ85569.1 - 0.0013 18.8 0.4 0.0035 17.5 0.0 1.8 2 0 0 2 2 2 1 QueF-like protein HATPase_c PF02518.26 EAQ85570.1 - 4.3e-28 98.1 0.0 8.7e-28 97.1 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EAQ85570.1 - 2.2e-25 89.0 0.1 4e-25 88.1 0.1 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 EAQ85570.1 - 9.5e-17 60.8 0.0 2.7e-16 59.4 0.0 1.8 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.7 EAQ85570.1 - 8.4e-10 38.8 0.0 2.4e-09 37.4 0.0 1.9 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 EAQ85570.1 - 6.5e-08 32.6 0.0 3.2e-07 30.3 0.0 2.1 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.10 EAQ85570.1 - 2.2e-06 27.9 0.0 0.0017 18.6 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_8 PF13188.7 EAQ85570.1 - 0.038 14.0 0.0 5.4 7.2 0.0 2.7 2 0 0 2 2 2 0 PAS domain PAS_3 PF08447.12 EAQ85570.1 - 0.054 13.8 0.3 0.14 12.4 0.2 1.8 2 0 0 2 2 2 0 PAS fold Exo_endo_phos_2 PF14529.6 EAQ85571.1 - 2.7e-25 88.5 0.0 2.3e-24 85.5 0.0 2.7 3 0 0 3 3 3 1 Endonuclease-reverse transcriptase Chromo PF00385.24 EAQ85571.1 - 1.8e-14 53.4 0.6 3.7e-14 52.4 0.6 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Exo_endo_phos PF03372.23 EAQ85571.1 - 4.9e-05 23.0 0.1 0.00012 21.7 0.1 1.7 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-CCHC PF00098.23 EAQ85571.1 - 0.0071 16.4 2.5 0.0071 16.4 2.5 3.5 3 0 0 3 3 2 2 Zinc knuckle CASP_C PF08172.12 EAQ85571.1 - 0.022 14.1 2.2 0.051 12.9 2.2 1.5 1 0 0 1 1 1 0 CASP C terminal Herpes_UL6 PF01763.16 EAQ85571.1 - 0.023 13.2 1.8 0.038 12.5 1.8 1.2 1 0 0 1 1 1 0 Herpesvirus UL6 like SlyX PF04102.12 EAQ85571.1 - 0.078 13.6 8.1 0.34 11.5 8.1 2.2 1 1 0 1 1 1 0 SlyX DUF948 PF06103.11 EAQ85571.1 - 0.41 10.9 3.8 0.2 11.9 0.6 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) ADIP PF11559.8 EAQ85571.1 - 2.3 8.3 11.8 0.16 12.1 5.7 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding TEX13 PF15186.6 EAQ85571.1 - 2.9 7.5 6.4 7.5 6.2 5.5 2.2 2 0 0 2 2 2 0 Testis-expressed sequence 13 protein family PBP1_TM PF14812.6 EAQ85571.1 - 3 8.3 5.5 42 4.6 0.1 2.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Cnn_1N PF07989.11 EAQ85571.1 - 6.8 6.9 7.8 2.3 8.4 2.2 2.7 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 Importin_rep_3 PF18806.1 EAQ85572.1 - 0.15 12.1 0.0 0.34 11.0 0.0 1.5 1 0 0 1 1 1 0 Importin 13 repeat Abhydrolase_4 PF08386.10 EAQ85574.1 - 1.6e-22 79.5 0.0 3.6e-22 78.4 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.20 EAQ85574.1 - 2.6e-11 43.6 0.0 7.3e-11 42.2 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Methyltransf_12 PF08242.12 EAQ85575.1 - 9.1e-19 68.1 0.0 4e-18 66.0 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EAQ85575.1 - 1.4e-17 64.0 0.0 2.7e-17 63.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PS-DH PF14765.6 EAQ85575.1 - 1.7e-16 60.4 0.2 1e-15 57.8 0.2 1.9 1 1 1 2 2 2 1 Polyketide synthase dehydratase Methyltransf_11 PF08241.12 EAQ85575.1 - 4e-14 53.0 0.0 1.1e-13 51.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAQ85575.1 - 1.1e-13 51.7 0.0 3e-13 50.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAQ85575.1 - 4.1e-13 49.4 0.0 1e-12 48.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EAQ85575.1 - 3.1e-06 26.7 0.1 5.4e-06 25.9 0.1 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.9 EAQ85575.1 - 1.5e-05 24.9 0.1 2.8e-05 23.9 0.1 1.4 1 0 0 1 1 1 1 Lysine methyltransferase PCMT PF01135.19 EAQ85575.1 - 0.00011 22.0 0.0 0.00058 19.7 0.0 2.1 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_2 PF00891.18 EAQ85575.1 - 0.00026 20.3 0.0 0.00076 18.8 0.0 1.8 2 0 0 2 2 2 1 O-methyltransferase domain Methyltransf_33 PF10017.9 EAQ85575.1 - 0.00098 18.4 0.0 0.0038 16.4 0.0 1.8 2 0 0 2 2 2 1 Histidine-specific methyltransferase, SAM-dependent Methyltransf_8 PF05148.15 EAQ85575.1 - 0.13 12.1 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Hypothetical methyltransferase Dimer_Tnp_hAT PF05699.14 EAQ85576.1 - 1.7e-16 59.7 0.3 2.3e-16 59.3 0.3 1.2 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Acyl_transf_1 PF00698.21 EAQ85577.1 - 6.3e-19 68.6 1.5 5.2e-13 49.2 0.9 2.1 1 1 1 2 2 2 2 Acyl transferase domain KAsynt_C_assoc PF16197.5 EAQ85577.1 - 2.3e-16 60.2 0.0 4.3e-16 59.4 0.0 1.4 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension zf-RVT PF13966.6 EAQ85578.1 - 0.0014 19.3 0.3 0.02 15.6 0.0 2.7 2 1 0 2 2 2 1 zinc-binding in reverse transcriptase ketoacyl-synt PF00109.26 EAQ85579.1 - 5.8e-17 62.1 0.0 6.9e-17 61.9 0.0 1.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Glyco_hydro_6 PF01341.17 EAQ85581.1 - 1.4e-104 350.2 0.1 1.8e-104 349.8 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 GTP_cyclohydro2 PF00925.20 EAQ85582.1 - 6.3e-37 126.7 0.1 7.3e-37 126.5 0.1 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase II Ribosomal_S24e PF01282.19 EAQ85584.1 - 3.2e-35 119.9 0.1 5.6e-35 119.1 0.1 1.4 1 1 0 1 1 1 1 Ribosomal protein S24e Zn_clus PF00172.18 EAQ85585.1 - 2e-08 34.2 7.4 2.8e-08 33.7 7.4 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pro_isomerase PF00160.21 EAQ85586.1 - 1.9e-33 116.0 0.0 2.8e-33 115.4 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 EAQ85586.1 - 8.2e-17 60.8 0.0 1.5e-16 59.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HEPN_RES_NTD1 PF18870.1 EAQ85588.1 - 0.077 13.2 0.7 0.13 12.5 0.7 1.3 1 0 0 1 1 1 0 HEPN/RES N-terminal domain 1 RPA43_OB PF17875.1 EAQ85589.1 - 1.5e-36 125.8 0.1 1.5e-36 125.8 0.1 4.0 2 1 0 2 2 2 1 RPA43 OB domain in RNA Pol I SHS2_Rpb7-N PF03876.17 EAQ85589.1 - 2e-06 28.0 0.0 3.5e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Sugar_tr PF00083.24 EAQ85590.1 - 1e-79 268.5 24.0 2.3e-78 264.1 24.0 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EAQ85590.1 - 7e-29 100.8 29.6 7e-29 100.8 29.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily NmrA PF05368.13 EAQ85590.1 - 1.3e-28 100.2 0.0 1.9e-28 99.6 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EAQ85590.1 - 6.8e-12 45.6 0.0 1.3e-11 44.8 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding TRI12 PF06609.13 EAQ85590.1 - 8.9e-09 34.3 3.8 1.9e-08 33.3 3.8 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Epimerase PF01370.21 EAQ85590.1 - 2.3e-06 27.3 0.1 5.8e-06 25.9 0.1 1.7 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EAQ85590.1 - 1.2e-05 24.4 0.0 1.8e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 EAQ85590.1 - 0.00023 21.1 0.1 0.0004 20.4 0.1 1.3 1 0 0 1 1 1 1 KR domain Semialdhyde_dh PF01118.24 EAQ85590.1 - 0.00083 19.8 0.0 0.0017 18.8 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 EAQ85590.1 - 0.0035 16.5 0.1 0.0067 15.6 0.0 1.5 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.25 EAQ85590.1 - 0.0044 16.5 0.1 0.0088 15.5 0.1 1.5 1 0 0 1 1 1 1 short chain dehydrogenase GDP_Man_Dehyd PF16363.5 EAQ85590.1 - 0.011 15.1 0.1 0.016 14.6 0.1 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Sacchrp_dh_NADP PF03435.18 EAQ85590.1 - 0.012 15.8 0.0 0.026 14.8 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 EAQ85590.1 - 0.055 13.7 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain Actin PF00022.19 EAQ85591.1 - 2.5e-112 375.5 0.0 1.6e-111 372.8 0.0 1.8 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 EAQ85591.1 - 0.075 11.8 0.0 0.68 8.7 0.0 2.4 1 1 0 1 1 1 0 MreB/Mbl protein Actin_micro PF17003.5 EAQ85591.1 - 0.15 11.2 0.2 0.45 9.6 0.1 1.7 2 0 0 2 2 2 0 Putative actin-like family Pkinase PF00069.25 EAQ85592.1 - 7.7e-63 212.3 0.0 1e-62 211.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ85592.1 - 1.1e-30 106.8 0.0 2.2e-30 105.8 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EAQ85592.1 - 0.0075 15.3 0.0 0.011 14.7 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EAQ85592.1 - 0.067 13.1 0.0 0.41 10.5 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.6 EAQ85592.1 - 0.12 11.6 0.0 0.24 10.7 0.0 1.5 1 1 0 1 1 1 0 Kinase-like Arf PF00025.21 EAQ85593.1 - 8.6e-57 191.4 0.3 4.1e-36 124.1 0.3 2.0 1 1 1 2 2 2 2 ADP-ribosylation factor family G-alpha PF00503.20 EAQ85593.1 - 2.8e-09 36.6 0.8 9.3e-05 21.7 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 EAQ85593.1 - 4.4e-09 36.6 0.1 7.4e-09 35.9 0.1 1.5 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EAQ85593.1 - 5.6e-07 29.3 0.1 1.6e-06 27.8 0.1 1.8 1 1 0 1 1 1 1 Ras family SRPRB PF09439.10 EAQ85593.1 - 4.9e-06 26.1 0.3 6.9e-05 22.4 0.0 2.0 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 EAQ85593.1 - 1.9e-05 24.1 0.0 2.2e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region 6PF2K PF01591.18 EAQ85593.1 - 0.0067 15.8 0.1 0.0089 15.4 0.1 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase MMR_HSR1 PF01926.23 EAQ85593.1 - 0.0099 16.0 0.0 0.014 15.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF4901 PF16244.5 EAQ85593.1 - 0.065 12.6 0.0 0.081 12.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4901) DUF1325 PF07039.11 EAQ85594.1 - 2e-35 121.8 0.1 3.4e-35 121.0 0.1 1.4 1 0 0 1 1 1 1 SGF29 tudor-like domain Atrophin-1 PF03154.15 EAQ85594.1 - 0.0047 15.3 2.5 0.0081 14.5 2.5 1.3 1 0 0 1 1 1 1 Atrophin-1 family LBR_tudor PF09465.10 EAQ85594.1 - 0.0053 16.5 0.1 0.13 12.1 0.0 2.5 3 0 0 3 3 3 1 Lamin-B receptor of TUDOR domain NPCBM PF08305.11 EAQ85594.1 - 0.078 13.2 0.6 5.5 7.2 0.5 2.2 2 0 0 2 2 2 0 NPCBM/NEW2 domain DUF3915 PF13054.6 EAQ85594.1 - 3.7 7.6 7.0 7.6 6.5 7.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) RSB_motif PF16294.5 EAQ85594.1 - 5.8 7.2 8.9 4.5 7.6 6.8 1.9 2 0 0 2 2 2 0 RNSP1-SAP18 binding (RSB) motif PMI_typeI PF01238.21 EAQ85595.1 - 4.8e-139 463.7 0.0 5.6e-139 463.5 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I AraC_binding PF02311.19 EAQ85595.1 - 0.0078 16.1 0.0 2.9 7.8 0.0 2.7 3 0 0 3 3 3 2 AraC-like ligand binding domain AMP-binding PF00501.28 EAQ85597.1 - 1e-48 166.0 0.4 3.9e-34 118.0 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 EAQ85597.1 - 1.8e-09 38.5 0.1 5.4e-09 36.9 0.1 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain FAD_binding_3 PF01494.19 EAQ85600.1 - 7.7e-07 28.7 1.9 0.0035 16.7 0.1 2.7 3 0 0 3 3 3 2 FAD binding domain NAD_binding_8 PF13450.6 EAQ85600.1 - 0.00034 20.8 0.0 0.00072 19.7 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EAQ85600.1 - 0.00038 20.1 0.5 0.00067 19.3 0.5 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EAQ85600.1 - 0.018 15.0 0.0 0.033 14.2 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 EAQ85600.1 - 0.032 13.5 0.0 0.053 12.8 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EAQ85600.1 - 0.057 12.7 0.0 0.082 12.1 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EAQ85600.1 - 0.081 12.0 0.2 0.14 11.2 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 EAQ85600.1 - 0.16 10.6 0.0 0.23 10.1 0.0 1.1 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.27 EAQ85600.1 - 0.2 12.2 0.2 0.39 11.3 0.2 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EAQ85600.1 - 0.27 10.0 0.2 0.39 9.5 0.2 1.1 1 0 0 1 1 1 0 Tryptophan halogenase TFIID-18kDa PF02269.16 EAQ85601.1 - 1.7e-20 72.8 1.6 3.6e-20 71.8 0.4 2.0 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit DUF2681 PF10883.8 EAQ85601.1 - 0.34 11.3 3.0 0.19 12.1 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) Ifi-6-16 PF06140.13 EAQ85602.1 - 0.0085 16.0 0.0 0.02 14.8 0.0 1.6 1 0 0 1 1 1 1 Interferon-induced 6-16 family MULE PF10551.9 EAQ85603.1 - 6e-23 81.1 0.0 1.1e-22 80.2 0.0 1.5 1 0 0 1 1 1 1 MULE transposase domain FAR1 PF03101.15 EAQ85603.1 - 0.023 15.4 0.0 0.05 14.3 0.0 1.6 1 0 0 1 1 1 0 FAR1 DNA-binding domain 7TM_GPCR_Srj PF10319.9 EAQ85603.1 - 0.096 12.0 0.0 0.14 11.4 0.0 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srj Peptidase_S8 PF00082.22 EAQ85604.1 - 5.5e-33 114.5 17.1 9.5e-33 113.7 17.1 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EAQ85604.1 - 1.7e-06 28.6 0.0 4e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 Peptidase inhibitor I9 Shugoshin_N PF07558.11 EAQ85605.1 - 0.0043 16.9 2.8 0.03 14.2 1.9 2.3 2 0 0 2 2 2 1 Shugoshin N-terminal coiled-coil region UPF0242 PF06785.11 EAQ85605.1 - 0.009 16.1 3.3 0.015 15.4 3.3 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus Leu_zip PF15294.6 EAQ85605.1 - 0.018 14.6 3.1 0.029 13.9 3.1 1.2 1 0 0 1 1 1 0 Leucine zipper Uds1 PF15456.6 EAQ85605.1 - 0.028 14.6 3.8 0.065 13.4 3.8 1.6 1 0 0 1 1 1 0 Up-regulated During Septation PKcGMP_CC PF16808.5 EAQ85605.1 - 0.034 14.0 1.4 0.077 12.9 1.4 1.6 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase GIT_CC PF16559.5 EAQ85605.1 - 0.076 12.9 1.3 0.17 11.8 1.3 1.6 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor SHE3 PF17078.5 EAQ85605.1 - 0.12 12.0 5.1 0.25 11.0 5.0 1.5 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 BBP1_C PF15272.6 EAQ85605.1 - 0.14 12.0 2.2 0.23 11.3 2.2 1.3 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal Cortex-I_coil PF09304.10 EAQ85605.1 - 0.18 12.1 3.5 0.42 10.8 3.1 1.8 1 1 0 1 1 1 0 Cortexillin I, coiled coil KASH_CCD PF14662.6 EAQ85605.1 - 0.26 11.1 8.9 0.62 9.9 8.9 1.5 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH MetOD2 PF18548.1 EAQ85605.1 - 0.41 10.8 2.7 0.49 10.5 1.4 1.8 2 0 0 2 2 1 0 Metanogen output domain 2 Rootletin PF15035.6 EAQ85605.1 - 0.66 10.0 10.1 2.1 8.4 8.8 2.0 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion CENP-H PF05837.12 EAQ85605.1 - 1.1 9.6 7.1 2.5 8.5 7.1 1.5 1 0 0 1 1 1 0 Centromere protein H (CENP-H) Exonuc_VII_L PF02601.15 EAQ85605.1 - 1.5 8.3 4.3 0.61 9.6 1.2 1.8 2 0 0 2 2 2 0 Exonuclease VII, large subunit Seryl_tRNA_N PF02403.22 EAQ85605.1 - 2.2 8.5 5.3 12 6.2 5.4 2.0 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF3552 PF12072.8 EAQ85605.1 - 2.4 7.5 10.7 4.6 6.6 10.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Ax_dynein_light PF10211.9 EAQ85605.1 - 8.6 6.3 8.7 14 5.5 8.7 1.3 1 0 0 1 1 1 0 Axonemal dynein light chain Peptidase_M20 PF01546.28 EAQ85606.1 - 5.6e-35 120.9 0.0 7.6e-35 120.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EAQ85606.1 - 4.2e-12 46.0 0.0 7.3e-12 45.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain DUF1967 PF09269.11 EAQ85606.1 - 0.15 12.0 0.0 1.2 9.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1967) Yippee-Mis18 PF03226.14 EAQ85607.1 - 1e-14 54.6 0.0 3.6e-14 52.8 0.0 1.8 1 1 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-dskA_traR PF01258.17 EAQ85607.1 - 0.22 11.5 1.8 2.1 8.3 0.2 2.7 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger Zn_ribbon_SprT PF17283.2 EAQ85607.1 - 4.2 7.4 7.5 2.1 8.3 0.3 3.1 3 0 0 3 3 3 0 SprT-like zinc ribbon domain ODC_AZ PF02100.17 EAQ85608.1 - 3e-41 140.0 0.0 4.1e-41 139.5 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme His_biosynth PF00977.21 EAQ85609.1 - 8.5e-49 166.1 0.7 3.1e-48 164.2 0.7 1.9 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.28 EAQ85609.1 - 4.6e-21 75.5 0.0 7.2e-21 74.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.19 EAQ85609.1 - 3.2e-07 30.4 0.0 4.3e-05 23.4 0.0 2.3 2 0 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.14 EAQ85609.1 - 1.2e-05 25.0 0.0 7.2e-05 22.5 0.0 2.0 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Dus PF01207.17 EAQ85609.1 - 0.034 13.3 0.1 0.082 12.0 0.0 1.6 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) Peptidase_C26 PF07722.13 EAQ85609.1 - 0.14 11.9 0.0 1.2 8.8 0.0 2.1 2 0 0 2 2 2 0 Peptidase C26 TFIIIC_sub6 PF10419.9 EAQ85610.1 - 5.6e-30 103.1 0.1 1.2e-29 102.0 0.1 1.6 1 0 0 1 1 1 1 TFIIIC subunit triple barrel domain S4_2 PF13275.6 EAQ85610.1 - 0.28 11.0 1.0 0.6 10.0 1.0 1.5 1 0 0 1 1 1 0 S4 domain Vps62 PF06101.11 EAQ85611.1 - 0.0017 16.7 0.2 0.0034 15.8 0.2 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 62 Dimer_Tnp_hAT PF05699.14 EAQ85612.1 - 2.3e-15 56.1 0.1 4.4e-15 55.3 0.1 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region RVT_1 PF00078.27 EAQ85613.1 - 1.1e-38 133.0 0.0 1e-37 129.8 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) EIAV_Rev PF11129.8 EAQ85613.1 - 0.052 13.7 0.4 0.66 10.2 0.2 2.5 2 0 0 2 2 2 0 Rev protein of equine infectious anaemia virus Glyco_hydro_11 PF00457.17 EAQ85617.1 - 1.4e-49 168.1 0.6 1.4e-49 168.1 0.6 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 11 CBM_1 PF00734.18 EAQ85617.1 - 4.3e-11 42.6 19.8 1.2e-10 41.2 19.8 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain FAD_binding_3 PF01494.19 EAQ85618.1 - 1.5e-07 31.0 0.0 3.4e-05 23.3 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Tyrosinase PF00264.20 EAQ85621.1 - 1.5e-26 94.1 0.0 1.8e-26 93.8 0.0 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase Peptidase_M16 PF00675.20 EAQ85622.1 - 7.6e-16 58.4 0.0 1.4e-15 57.5 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EAQ85622.1 - 3.5e-12 46.7 0.0 5.9e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase M16 inactive domain Importin_rep_3 PF18806.1 EAQ85624.1 - 0.026 14.5 0.0 0.057 13.5 0.0 1.5 1 0 0 1 1 1 0 Importin 13 repeat FAD_binding_9 PF08021.11 EAQ85624.1 - 0.034 14.3 0.0 0.066 13.4 0.0 1.4 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain PPDK_N PF01326.19 EAQ85626.1 - 1.2e-61 208.8 0.0 1.8e-61 208.2 0.0 1.2 1 0 0 1 1 1 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain PEP-utilizers_C PF02896.18 EAQ85626.1 - 1.5e-53 181.8 0.0 2.1e-53 181.4 0.0 1.1 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain Ldh_1_N PF00056.23 EAQ85627.1 - 1.9e-27 96.1 0.7 2.3e-27 95.8 0.7 1.1 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain PEP_hydrolase PF09370.10 EAQ85627.1 - 0.00023 20.5 0.0 0.00026 20.3 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate hydrolase-like Glyco_hydro_4 PF02056.16 EAQ85627.1 - 0.024 14.2 0.1 0.062 12.9 0.0 1.7 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase K_oxygenase PF13434.6 EAQ85627.1 - 0.19 10.8 0.2 0.39 9.8 0.1 1.4 1 1 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) F420_oxidored PF03807.17 EAQ85627.1 - 0.2 12.2 2.6 0.55 10.8 0.9 2.3 1 1 1 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 EAQ85627.1 - 0.21 11.2 1.7 0.38 10.4 1.7 1.7 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.14 EAQ85627.1 - 0.43 10.1 3.7 1.3 8.6 3.7 1.8 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Exo_endo_phos_2 PF14529.6 EAQ85628.1 - 2.3e-26 92.0 0.1 1.3e-25 89.5 0.0 2.4 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase RVT_1 PF00078.27 EAQ85628.1 - 1e-17 64.4 0.2 9e-17 61.3 0.0 2.3 3 0 0 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 EAQ85628.1 - 7.3e-05 22.4 0.4 0.00016 21.3 0.4 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-CCHC PF00098.23 EAQ85628.1 - 0.0069 16.4 2.5 0.0069 16.4 2.5 2.6 2 0 0 2 2 1 1 Zinc knuckle Herpes_UL6 PF01763.16 EAQ85628.1 - 0.016 13.8 0.9 0.027 13.0 0.9 1.2 1 0 0 1 1 1 0 Herpesvirus UL6 like SlyX PF04102.12 EAQ85628.1 - 0.058 14.0 7.8 0.19 12.3 7.2 2.3 1 1 0 1 1 1 0 SlyX CASP_C PF08172.12 EAQ85628.1 - 0.062 12.6 1.4 0.14 11.5 1.4 1.5 1 0 0 1 1 1 0 CASP C terminal DUF948 PF06103.11 EAQ85628.1 - 0.076 13.3 1.4 0.19 12.0 0.6 2.1 2 0 0 2 2 1 0 Bacterial protein of unknown function (DUF948) SKA1 PF07160.12 EAQ85628.1 - 0.11 12.4 1.6 0.26 11.1 1.6 1.6 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 Phage_lysis PF03245.13 EAQ85628.1 - 1.1 9.4 6.9 0.68 10.1 2.8 2.7 3 0 0 3 3 3 0 Bacteriophage Rz lysis protein ADIP PF11559.8 EAQ85628.1 - 2.6 8.1 11.8 0.15 12.1 5.7 1.9 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding TEX13 PF15186.6 EAQ85628.1 - 4 7.1 6.4 7.3 6.3 5.5 1.9 2 0 0 2 2 2 0 Testis-expressed sequence 13 protein family Cnn_1N PF07989.11 EAQ85628.1 - 8.5 6.6 7.8 2.2 8.5 2.2 2.5 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 DUF3439 PF11921.8 EAQ85629.1 - 0.13 12.2 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) LEM PF03020.15 EAQ85629.1 - 0.27 10.8 1.8 0.36 10.4 0.2 2.0 2 0 0 2 2 2 0 LEM domain AAA PF00004.29 EAQ85630.1 - 0.15 12.5 0.1 1.6 9.1 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RVT_1 PF00078.27 EAQ85633.1 - 1.1e-16 61.0 0.4 1.3e-08 34.6 0.0 3.9 2 1 2 4 4 4 3 Reverse transcriptase (RNA-dependent DNA polymerase) EIAV_Rev PF11129.8 EAQ85633.1 - 0.07 13.3 0.7 0.59 10.3 0.2 2.4 2 0 0 2 2 2 0 Rev protein of equine infectious anaemia virus Pkinase PF00069.25 EAQ85634.1 - 3.2e-24 85.7 0.0 3.1e-11 43.2 0.0 2.6 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ85634.1 - 1.4e-06 27.8 0.0 0.025 13.9 0.0 2.8 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.23 EAQ85634.1 - 2.5e-05 24.3 1.5 0.00031 20.7 0.2 2.3 2 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EAQ85634.1 - 0.035 13.4 0.0 0.06 12.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EAQ85634.1 - 0.045 12.5 0.0 0.12 11.2 0.0 1.6 2 0 0 2 2 2 0 Fungal protein kinase FAD_binding_3 PF01494.19 EAQ85635.1 - 5.5e-12 45.6 0.0 1.2e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain NOA36 PF06524.12 EAQ85637.1 - 6.9 5.9 6.9 9.8 5.4 6.9 1.1 1 0 0 1 1 1 0 NOA36 protein Sugar_tr PF00083.24 EAQ85638.1 - 3.5e-69 233.8 20.8 2.6e-67 227.6 15.2 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EAQ85638.1 - 8.1e-17 61.2 19.3 8.1e-17 61.2 19.3 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF4293 PF14126.6 EAQ85638.1 - 0.69 10.1 6.7 0.29 11.4 3.6 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) Chromo PF00385.24 EAQ85639.1 - 4.4e-05 23.3 1.2 0.00016 21.5 0.5 2.2 1 1 1 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain PPP1R35_C PF15503.6 EAQ85640.1 - 8.3 6.2 15.1 0.56 10.0 4.4 2.5 2 0 0 2 2 2 0 Protein phosphatase 1 regulatory subunit 35 C-terminus NDUF_B7 PF05676.13 EAQ85641.1 - 8.6e-30 102.3 6.4 1e-29 102.0 6.4 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.10 EAQ85641.1 - 0.0053 16.8 3.4 0.0054 16.7 2.8 1.4 1 1 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Glyco_hydro_61 PF03443.14 EAQ85642.1 - 2.7e-50 171.2 0.0 3.4e-50 170.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF1996 PF09362.10 EAQ85644.1 - 8.5e-77 258.3 1.4 1e-76 258.0 1.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Abhydrolase_4 PF08386.10 EAQ85645.1 - 9.6e-21 73.8 0.0 1.7e-20 73.0 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.20 EAQ85645.1 - 8.4e-12 45.3 0.0 4.6e-09 36.3 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Pkinase PF00069.25 EAQ85646.1 - 0.0013 18.2 0.0 0.69 9.2 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ85646.1 - 0.002 17.5 0.0 1.8 7.8 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Dimer_Tnp_hAT PF05699.14 EAQ85647.1 - 5.8e-12 45.2 0.1 1.8e-11 43.6 0.1 1.8 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Alanine_zipper PF11839.8 EAQ85647.1 - 0.016 15.6 6.8 0.068 13.5 6.8 2.1 1 0 0 1 1 1 0 Alanine-zipper, major outer membrane lipoprotein CENP-F_leu_zip PF10473.9 EAQ85647.1 - 0.068 13.2 5.6 0.48 10.4 1.7 2.7 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Borrelia_P83 PF05262.11 EAQ85647.1 - 1.1 7.7 4.8 1.7 7.0 2.9 2.0 2 0 0 2 2 2 0 Borrelia P83/100 protein EamA PF00892.20 EAQ85648.1 - 2.1e-11 44.2 30.2 2.5e-06 27.7 1.5 2.7 3 0 0 3 3 3 2 EamA-like transporter family DUF202 PF02656.15 EAQ85648.1 - 0.017 15.5 1.0 0.017 15.5 1.0 4.0 4 2 0 4 4 4 0 Domain of unknown function (DUF202) PRRSV_Env PF02340.15 EAQ85648.1 - 3.8 6.8 11.5 12 5.2 0.1 3.1 2 1 1 3 3 3 0 PRRSV putative envelope protein Ank PF00023.30 EAQ85649.1 - 1.3e-09 38.0 0.2 0.0017 18.8 0.1 3.5 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 EAQ85649.1 - 1.5e-09 38.2 0.0 0.0014 19.1 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAQ85649.1 - 1.6e-09 38.2 0.0 0.0026 18.3 0.2 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAQ85649.1 - 4.8e-07 29.6 0.0 0.078 13.6 0.0 3.7 4 0 0 4 4 4 2 Ankyrin repeat KilA-N PF04383.13 EAQ85649.1 - 6e-07 29.3 0.2 5.5e-06 26.2 0.2 2.3 1 1 0 1 1 1 1 KilA-N domain Ank_5 PF13857.6 EAQ85649.1 - 3.6e-06 27.1 0.0 0.017 15.4 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) MbeD_MobD PF04899.12 EAQ85649.1 - 0.026 14.6 2.5 0.063 13.4 1.8 2.1 1 1 0 1 1 1 0 MbeD/MobD like DUF3573 PF12097.8 EAQ85649.1 - 0.23 10.3 0.1 0.36 9.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) UPF0242 PF06785.11 EAQ85649.1 - 1 9.4 7.4 3.8 7.6 7.4 2.0 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF4407 PF14362.6 EAQ85649.1 - 7.5 5.8 16.1 0.19 11.0 6.5 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) CXCXC PF03128.14 EAQ85650.1 - 0.13 12.8 0.1 0.26 11.8 0.1 1.5 1 0 0 1 1 1 0 CXCXC repeat Glyco_hydro_52 PF03512.13 EAQ85653.1 - 0.033 13.2 4.6 0.049 12.6 4.6 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 52 Folate_carrier PF01770.18 EAQ85653.1 - 1.3 7.6 4.9 2 7.1 4.9 1.2 1 0 0 1 1 1 0 Reduced folate carrier Aldo_ket_red PF00248.21 EAQ85656.1 - 3.4e-36 125.0 0.0 3.9e-36 124.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family APC_u13 PF16634.5 EAQ85656.1 - 0.15 12.0 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 Unstructured region on APC between APC_crr and SAMP TPR_12 PF13424.6 EAQ85657.1 - 2.8e-12 46.7 0.7 3.9e-06 27.1 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat PNP_UDP_1 PF01048.20 EAQ85657.1 - 1.1e-09 37.9 0.3 5.7e-09 35.6 0.3 2.2 1 1 0 1 1 1 1 Phosphorylase superfamily TPR_14 PF13428.6 EAQ85657.1 - 2.1e-07 31.2 3.6 1.1 10.2 0.3 6.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.6 EAQ85657.1 - 4.1e-06 26.5 8.0 2.6 8.0 0.7 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat NB-ARC PF00931.22 EAQ85657.1 - 2.2e-05 23.8 0.0 5e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain TPR_2 PF07719.17 EAQ85657.1 - 0.00039 20.3 0.2 0.75 10.1 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 EAQ85657.1 - 0.00048 20.6 3.7 0.57 10.7 1.4 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 EAQ85657.1 - 0.00083 20.0 3.3 0.1 13.2 2.6 3.8 4 0 0 4 4 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EAQ85657.1 - 0.0038 17.4 0.0 3.2 8.0 0.0 3.7 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 NACHT PF05729.12 EAQ85657.1 - 0.0038 17.2 0.0 0.0093 15.9 0.0 1.7 1 0 0 1 1 1 1 NACHT domain TPR_8 PF13181.6 EAQ85657.1 - 0.0076 16.4 0.5 42 4.7 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 EAQ85657.1 - 0.0091 16.0 0.6 20 5.5 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat RPN6_N PF18055.1 EAQ85657.1 - 0.016 15.6 0.7 2.8 8.3 0.2 3.4 3 0 0 3 3 3 0 26S proteasome regulatory subunit RPN6 N-terminal domain TPR_MalT PF17874.1 EAQ85657.1 - 0.074 12.4 1.1 1.1 8.6 0.6 2.6 2 1 0 3 3 3 0 MalT-like TPR region AAA_25 PF13481.6 EAQ85657.1 - 0.088 12.4 0.0 0.22 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain TPR_4 PF07721.14 EAQ85657.1 - 0.11 13.2 0.0 21 6.1 2.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 EAQ85657.1 - 0.15 12.7 1.6 1.1e+02 3.7 0.0 4.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Peroxin-13_N PF04088.13 EAQ85658.1 - 0.097 13.0 0.0 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 Peroxin 13, N-terminal region HeLo PF14479.6 EAQ85659.1 - 6.1e-45 153.6 0.1 1.6e-44 152.2 0.1 1.8 1 1 0 1 1 1 1 Prion-inhibition and propagation Aa_trans PF01490.18 EAQ85661.1 - 7.4e-44 150.1 33.8 9.2e-44 149.8 33.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Esterase_phd PF10503.9 EAQ85662.1 - 6.8e-25 87.9 1.6 8.9e-25 87.5 1.6 1.1 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 EAQ85662.1 - 2.4e-10 40.3 0.3 3.5e-10 39.7 0.3 1.3 1 1 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 EAQ85662.1 - 0.047 13.0 0.3 4.3 6.5 0.2 2.1 1 1 1 2 2 2 0 Serine aminopeptidase, S33 Esterase PF00756.20 EAQ85662.1 - 0.056 13.1 0.3 0.091 12.4 0.2 1.5 2 0 0 2 2 2 0 Putative esterase Abhydrolase_2 PF02230.16 EAQ85662.1 - 0.11 12.2 0.1 8.4 6.1 0.1 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Abhydrolase_2 PF02230.16 EAQ85663.1 - 0.00011 22.2 0.0 0.00021 21.2 0.0 1.4 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Esterase PF00756.20 EAQ85663.1 - 0.012 15.3 0.2 0.2 11.2 0.2 2.3 1 1 0 1 1 1 0 Putative esterase NB-ARC PF00931.22 EAQ85664.1 - 0.077 12.2 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain TOM20_plant PF06552.12 EAQ85665.1 - 0.01 15.6 0.0 0.016 15.0 0.0 1.2 1 0 0 1 1 1 0 Plant specific mitochondrial import receptor subunit TOM20 Sugar_tr PF00083.24 EAQ85666.1 - 1.5e-96 324.0 22.8 1.5e-67 228.5 10.3 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EAQ85666.1 - 2.5e-17 62.9 26.5 3.2e-09 36.2 4.6 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Serglycin PF04360.12 EAQ85666.1 - 0.25 11.3 1.8 0.51 10.3 1.8 1.5 1 0 0 1 1 1 0 Serglycin Peptidase_M43 PF05572.13 EAQ85667.1 - 5.2e-06 26.4 0.2 1.3e-05 25.2 0.1 1.7 1 1 1 2 2 2 1 Pregnancy-associated plasma protein-A polyprenyl_synt PF00348.17 EAQ85668.1 - 3.2e-42 144.4 0.0 5.7e-42 143.5 0.0 1.4 1 0 0 1 1 1 1 Polyprenyl synthetase Terpene_synth_C PF03936.16 EAQ85668.1 - 0.002 17.5 0.0 0.0043 16.4 0.0 1.5 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain Dioxygenase_C PF00775.21 EAQ85669.1 - 4.8e-06 26.1 0.1 7.6e-06 25.5 0.1 1.3 1 0 0 1 1 1 1 Dioxygenase PAN_1 PF00024.26 EAQ85670.1 - 1.4e-10 41.0 16.5 0.00087 19.2 1.0 3.5 3 0 0 3 3 3 3 PAN domain PAN_4 PF14295.6 EAQ85670.1 - 4e-06 26.6 13.9 0.016 15.1 0.3 4.2 4 0 0 4 4 4 2 PAN domain PAN_3 PF08277.12 EAQ85670.1 - 0.19 11.6 6.4 13 5.7 0.4 3.5 3 0 0 3 3 3 0 PAN-like domain MANEC PF07502.14 EAQ85670.1 - 0.2 12.0 12.5 0.28 11.5 0.1 3.5 3 0 0 3 3 3 0 MANEC domain Rhodanese PF00581.20 EAQ85672.1 - 0.00022 21.7 0.0 0.0004 20.9 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain Hexapep PF00132.24 EAQ85674.1 - 3.4e-09 36.1 5.0 0.00045 19.8 0.7 4.5 3 1 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EAQ85674.1 - 4.9e-05 23.0 0.2 0.44 10.4 0.0 3.2 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Epimerase PF01370.21 EAQ85675.1 - 2.7e-08 33.6 0.0 9.7e-08 31.8 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EAQ85675.1 - 2.3e-05 23.9 0.0 3.6e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EAQ85675.1 - 0.00015 21.7 0.6 0.00024 21.0 0.6 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EAQ85675.1 - 0.00041 20.0 0.1 0.00063 19.4 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 EAQ85675.1 - 0.0013 17.8 0.0 0.0018 17.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RhlB PF12300.8 EAQ85677.1 - 3 8.0 14.4 6.5 6.9 14.4 1.5 1 0 0 1 1 1 0 ATP-dependent RNA helicase RhlB Zn-ribbon_8 PF09723.10 EAQ85678.1 - 1.2 9.3 3.9 3.7 7.7 3.9 1.8 1 0 0 1 1 1 0 Zinc ribbon domain 2OG-FeII_Oxy_2 PF13532.6 EAQ85679.1 - 1.6e-17 64.4 0.0 1.4e-16 61.3 0.0 2.3 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Pkinase PF00069.25 EAQ85680.1 - 0.05 13.0 0.0 11 5.3 0.0 2.5 3 0 0 3 3 3 0 Protein kinase domain NAS PF03059.16 EAQ85681.1 - 2.3e-64 217.4 0.2 1.2e-34 120.0 0.0 2.0 1 1 1 2 2 2 2 Nicotianamine synthase protein Methyltransf_25 PF13649.6 EAQ85681.1 - 0.071 13.8 0.0 0.22 12.3 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain ATPgrasp_N PF18130.1 EAQ85682.1 - 3.5e-15 56.3 0.1 7.9e-15 55.2 0.1 1.6 1 0 0 1 1 1 1 ATP-grasp N-terminal domain ATP-grasp_4 PF13535.6 EAQ85682.1 - 3.9e-08 33.1 0.0 1.7e-07 31.0 0.0 2.0 1 1 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 EAQ85682.1 - 0.0004 20.0 0.0 0.00071 19.2 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus CSD2 PF17876.1 EAQ85682.1 - 0.07 13.3 0.0 10 6.4 0.0 2.3 2 0 0 2 2 2 0 Cold shock domain Lipocalin_2 PF08212.12 EAQ85684.1 - 3.4e-16 59.5 0.0 4.3e-16 59.1 0.0 1.1 1 0 0 1 1 1 1 Lipocalin-like domain Lipocalin PF00061.23 EAQ85684.1 - 0.00069 19.8 0.0 0.0011 19.2 0.0 1.4 1 1 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family ApoM PF11032.8 EAQ85684.1 - 0.12 12.0 0.0 2.1 8.0 0.0 2.1 2 0 0 2 2 2 0 ApoM domain VSP PF03302.13 EAQ85685.1 - 0.0024 16.8 0.3 0.003 16.5 0.3 1.1 1 0 0 1 1 1 1 Giardia variant-specific surface protein SKG6 PF08693.10 EAQ85685.1 - 0.0038 16.6 2.2 0.0058 16.0 0.5 2.0 2 0 0 2 2 2 1 Transmembrane alpha-helix domain DUF4448 PF14610.6 EAQ85685.1 - 0.059 13.1 0.0 0.16 11.7 0.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF4448) DUF3318 PF11780.8 EAQ85685.1 - 0.14 12.1 0.1 0.21 11.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3318) MLANA PF14991.6 EAQ85685.1 - 0.18 12.1 0.0 0.25 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein melan-A DUF4307 PF14155.6 EAQ85685.1 - 0.21 11.4 0.6 0.52 10.2 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4307) Peptidase_M57 PF12388.8 EAQ85686.1 - 0.014 15.0 1.1 1.5 8.4 0.2 2.1 1 1 1 2 2 2 0 Dual-action HEIGH metallo-peptidase 4HBT_2 PF13279.6 EAQ85688.1 - 0.0074 16.8 0.0 0.011 16.3 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily DUF3455 PF11937.8 EAQ85691.1 - 1.8e-12 48.0 0.0 2.5e-12 47.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) C2 PF00168.30 EAQ85692.1 - 1.4e-16 60.6 0.0 2.4e-16 59.9 0.0 1.4 1 0 0 1 1 1 1 C2 domain Glyco_hydro_47 PF01532.20 EAQ85693.1 - 9.4e-154 512.7 0.0 1.1e-153 512.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 TMEM234 PF10639.9 EAQ85694.1 - 3e-28 98.2 0.2 5.6e-28 97.3 0.2 1.4 1 1 0 1 1 1 1 Putative transmembrane family 234 Proteasome PF00227.26 EAQ85697.1 - 7.2e-48 162.6 0.0 1.2e-47 161.9 0.0 1.3 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EAQ85697.1 - 1.4e-13 50.2 0.1 1.4e-13 50.2 0.1 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature YnfE PF17452.2 EAQ85697.1 - 0.093 13.0 0.0 0.29 11.5 0.0 1.8 1 1 1 2 2 2 0 Uncharacterized YnfE-like DUF2373 PF10180.9 EAQ85698.1 - 5.5e-25 87.0 0.5 2.6e-24 84.8 0.1 2.1 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2373) DUF572 PF04502.13 EAQ85698.1 - 8.9 5.8 42.0 0.14 11.7 23.3 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF572) SIS PF01380.22 EAQ85699.1 - 5e-12 45.8 1.8 7.7e-12 45.2 0.3 2.0 2 1 0 2 2 2 1 SIS domain SIS_2 PF13580.6 EAQ85699.1 - 0.00016 21.7 0.0 0.00083 19.4 0.1 2.0 1 1 1 2 2 2 1 SIS domain LMWPc PF01451.21 EAQ85700.1 - 1.3e-36 126.1 0.0 1.8e-36 125.7 0.0 1.1 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Pkinase PF00069.25 EAQ85701.1 - 2e-69 233.9 0.0 2.5e-69 233.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ85701.1 - 1.4e-31 109.7 0.0 1.9e-31 109.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EAQ85701.1 - 0.0075 15.3 0.0 0.014 14.4 0.0 1.5 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EAQ85701.1 - 0.039 13.3 0.1 0.076 12.4 0.1 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EAQ85701.1 - 0.047 13.6 0.1 0.16 11.9 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family UTP15_C PF09384.10 EAQ85702.1 - 1.7e-51 173.8 0.0 2.4e-51 173.3 0.0 1.2 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.32 EAQ85702.1 - 3.2e-17 62.6 4.7 5.2e-05 23.9 0.0 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAQ85702.1 - 8.7e-05 22.7 0.1 0.5 10.7 0.0 4.2 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain zf-MIZ PF02891.20 EAQ85703.1 - 2.2e-08 33.7 8.4 3.8e-06 26.6 8.4 2.7 1 1 0 1 1 1 1 MIZ/SP-RING zinc finger DUF3464 PF11947.8 EAQ85703.1 - 0.43 10.3 9.6 0.96 9.2 9.6 1.5 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Presenilin PF01080.17 EAQ85703.1 - 0.66 8.7 7.1 1.3 7.7 7.1 1.4 1 0 0 1 1 1 0 Presenilin SpoIIP PF07454.11 EAQ85703.1 - 1.4 8.4 7.5 2.2 7.6 7.5 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Kei1 PF08552.11 EAQ85703.1 - 1.8 8.4 2.9 3.7 7.4 2.9 1.4 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 RR_TM4-6 PF06459.12 EAQ85703.1 - 6.4 6.5 8.0 12 5.6 8.0 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 MULE PF10551.9 EAQ85708.1 - 1.3e-27 96.0 0.1 3.1e-27 94.8 0.1 1.7 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.18 EAQ85708.1 - 0.004 16.1 0.0 0.0076 15.2 0.0 1.4 1 0 0 1 1 1 1 Transposase, Mutator family Hamartin PF04388.12 EAQ85708.1 - 0.86 8.2 12.7 2.1 6.9 12.7 1.6 1 0 0 1 1 1 0 Hamartin protein Rrn6 PF10214.9 EAQ85708.1 - 1.5 7.2 22.2 2.3 6.6 22.2 1.3 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Macoilin PF09726.9 EAQ85708.1 - 7.7 4.9 10.7 17 3.8 9.5 1.8 2 0 0 2 2 2 0 Macoilin family MULE PF10551.9 EAQ85710.1 - 3.8e-31 107.4 0.2 9.4e-28 96.5 0.0 2.9 2 0 0 2 2 2 2 MULE transposase domain Transposase_mut PF00872.18 EAQ85710.1 - 8.5e-05 21.6 0.3 0.0016 17.4 0.0 2.3 2 0 0 2 2 2 1 Transposase, Mutator family MULE PF10551.9 EAQ85711.1 - 2.8e-23 82.2 0.1 7e-23 80.9 0.0 1.7 2 0 0 2 2 2 1 MULE transposase domain Transposase_mut PF00872.18 EAQ85711.1 - 0.00048 19.1 0.0 0.00077 18.4 0.0 1.2 1 0 0 1 1 1 1 Transposase, Mutator family ADD_DNMT3 PF17980.1 EAQ85713.1 - 0.14 12.1 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 Cysteine rich ADD domain in DNMT3 Arrestin_N PF00339.29 EAQ85714.1 - 1.1e-14 54.7 0.0 3.5e-09 36.9 0.0 2.7 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain RrnaAD PF00398.20 EAQ85715.1 - 7.1e-44 149.9 0.0 9.9e-44 149.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 EAQ85715.1 - 0.0015 19.2 0.0 0.003 18.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EAQ85715.1 - 0.041 13.2 0.0 0.061 12.6 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase MTS PF05175.14 EAQ85715.1 - 0.1 12.1 0.0 0.22 11.1 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase small domain Met_10 PF02475.16 EAQ85715.1 - 0.13 12.0 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Met-10+ like-protein RRN3 PF05327.11 EAQ85715.1 - 8.7 4.7 9.0 12 4.3 9.0 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF2968 PF11180.8 EAQ85716.1 - 0.11 12.1 1.5 0.23 11.1 1.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) NPV_P10 PF05531.12 EAQ85716.1 - 0.13 12.7 3.2 0.45 11.0 0.2 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DHH PF01368.20 EAQ85716.1 - 0.87 9.9 0.0 0.87 9.9 0.0 2.7 3 0 0 3 3 3 0 DHH family ExsD PF16806.5 EAQ85716.1 - 1.3 8.9 3.1 0.57 10.1 0.1 1.8 2 0 0 2 2 2 0 Antiactivator protein ExsD XhlA PF10779.9 EAQ85716.1 - 4.5 7.6 4.6 33 4.8 0.2 2.4 1 1 1 2 2 2 0 Haemolysin XhlA SesA PF17107.5 EAQ85718.1 - 1.8e-25 89.5 0.5 8e-14 51.9 0.0 3.1 2 1 1 3 3 3 2 N-terminal domain on NACHT_NTPase and P-loop NTPases NACHT PF05729.12 EAQ85718.1 - 4.2e-15 56.1 0.0 9.2e-15 54.9 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EAQ85718.1 - 0.0018 18.7 0.0 0.0046 17.4 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain PIF1 PF05970.14 EAQ85718.1 - 0.012 14.8 0.1 0.03 13.5 0.1 1.7 1 1 0 1 1 1 0 PIF1-like helicase AAA_19 PF13245.6 EAQ85718.1 - 0.016 15.6 0.1 0.11 12.9 0.1 2.2 1 1 0 1 1 1 0 AAA domain AFG1_ATPase PF03969.16 EAQ85718.1 - 0.1 11.4 0.0 0.2 10.5 0.0 1.4 1 0 0 1 1 1 0 AFG1-like ATPase AAA_30 PF13604.6 EAQ85718.1 - 0.15 11.7 0.1 0.36 10.5 0.1 1.5 1 0 0 1 1 1 0 AAA domain Ribosomal_L16 PF00252.18 EAQ85719.1 - 7.7e-45 152.1 0.0 9.7e-45 151.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Ribosomal_L7Ae PF01248.26 EAQ85720.1 - 5.3e-23 80.6 0.0 6e-23 80.4 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Herpes_UL6 PF01763.16 EAQ85721.1 - 0.071 11.6 5.4 0.12 10.9 5.4 1.3 1 0 0 1 1 1 0 Herpesvirus UL6 like ATG16 PF08614.11 EAQ85721.1 - 1.5 9.0 34.0 0.029 14.6 16.3 3.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) TTKRSYEDQ PF10212.9 EAQ85721.1 - 3.4 6.5 13.2 0.21 10.5 5.3 2.3 2 1 1 3 3 3 0 Predicted coiled-coil domain-containing protein Fez1 PF06818.15 EAQ85721.1 - 5.7 7.3 27.7 0.11 13.0 15.9 2.3 2 0 0 2 2 2 0 Fez1 Fib_alpha PF08702.10 EAQ85721.1 - 6 7.0 15.6 1.6 8.9 5.7 3.0 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Acetyltransf_2 PF00797.17 EAQ85722.1 - 1.3e-35 123.4 0.0 2.7e-35 122.3 0.0 1.5 1 1 0 1 1 1 1 N-acetyltransferase Vac7 PF12751.7 EAQ85723.1 - 4.6e-140 467.4 14.6 3.1e-123 412.0 3.1 3.1 3 0 0 3 3 3 2 Vacuolar segregation subunit 7 FA_desaturase PF00487.24 EAQ85724.1 - 8.9e-25 88.0 16.4 1.3e-24 87.4 16.4 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.10 EAQ85724.1 - 3.6e-18 64.8 0.1 6.3e-18 64.0 0.1 1.4 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) Aldo_ket_red PF00248.21 EAQ85725.1 - 8.1e-69 232.0 0.1 9.2e-69 231.9 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family MHB PF16525.5 EAQ85725.1 - 0.13 12.5 0.0 0.27 11.5 0.0 1.5 1 0 0 1 1 1 0 Haemophore, haem-binding zf-CCHC PF00098.23 EAQ85726.1 - 4e-49 162.6 78.4 1.6e-07 31.1 3.7 10.3 10 0 0 10 10 10 10 Zinc knuckle zf-CCHC_2 PF13696.6 EAQ85726.1 - 7.7e-13 48.0 69.5 8.3e-05 22.3 1.6 10.1 10 0 0 10 10 10 9 Zinc knuckle zf-CCHC_3 PF13917.6 EAQ85726.1 - 1.5e-06 28.1 53.8 0.016 15.2 0.6 8.9 3 3 6 9 9 9 5 Zinc knuckle zf-CCHC_4 PF14392.6 EAQ85726.1 - 4.7e-06 26.2 51.8 0.11 12.2 0.6 9.2 8 1 1 9 9 9 6 Zinc knuckle zf-CCHC_6 PF15288.6 EAQ85726.1 - 0.00029 20.6 57.7 0.014 15.2 0.5 8.5 6 2 3 9 9 9 5 Zinc knuckle Methyltransf_23 PF13489.6 EAQ85727.1 - 8.9e-15 54.9 0.0 1.4e-14 54.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EAQ85727.1 - 5.7e-08 33.3 0.0 8.1e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAQ85727.1 - 9.9e-07 29.4 0.0 1.4e-06 28.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EAQ85727.1 - 4.7e-06 27.3 0.0 6.5e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAQ85727.1 - 0.0087 15.9 0.0 0.014 15.2 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain DDE_1 PF03184.19 EAQ85728.1 - 6.5e-17 61.7 0.0 1.2e-16 60.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 EAQ85728.1 - 1.7e-14 53.6 0.0 3.5e-14 52.6 0.0 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.16 EAQ85728.1 - 1.9e-05 24.3 0.0 5e-05 23.0 0.0 1.7 2 0 0 2 2 2 1 helix-turn-helix, Psq domain HTH_23 PF13384.6 EAQ85728.1 - 0.0095 15.7 0.0 0.032 14.0 0.0 1.9 1 0 0 1 1 1 1 Homeodomain-like domain DDE_3 PF13358.6 EAQ85728.1 - 0.067 12.9 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 DDE superfamily endonuclease DnaJ_C PF01556.18 EAQ85730.1 - 4.9e-27 94.8 0.0 7.4e-27 94.3 0.0 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EAQ85730.1 - 4.5e-25 87.6 3.8 7.1e-25 86.9 3.8 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EAQ85730.1 - 2.7e-13 50.1 16.5 4.3e-13 49.4 16.5 1.3 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 EAQ85730.1 - 0.032 14.2 8.2 0.74 9.8 1.4 2.4 2 0 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 EAQ85730.1 - 0.058 13.4 8.1 0.22 11.6 0.9 2.3 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF3824 PF12868.7 EAQ85731.1 - 0.00047 20.8 10.0 0.00047 20.8 10.0 15.7 7 5 8 15 15 15 4 Domain of unknwon function (DUF3824) Ribosomal_60s PF00428.19 EAQ85732.1 - 6.2e-27 94.0 10.9 7.6e-27 93.7 10.9 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Phage_holin_6_1 PF09682.10 EAQ85732.1 - 0.34 11.4 2.8 1.9 8.9 0.2 2.1 2 0 0 2 2 2 0 Bacteriophage holin of superfamily 6 (Holin_LLH) DUF2408 PF10303.9 EAQ85733.1 - 3.9e-37 127.8 6.5 2.2e-23 83.3 0.2 4.5 3 2 1 4 4 4 3 Protein of unknown function (DUF2408) DUF2920 PF11144.8 EAQ85733.1 - 0.016 14.4 1.2 3.9 6.5 0.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2920) DUF4600 PF15372.6 EAQ85733.1 - 1.4 9.3 5.6 0.25 11.8 1.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4600) Laminin_II PF06009.12 EAQ85733.1 - 1.8 8.6 5.8 0.32 11.0 0.5 2.4 3 0 0 3 3 3 0 Laminin Domain II DUF1664 PF07889.12 EAQ85733.1 - 2.9 8.0 6.5 0.46 10.5 0.6 2.6 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) YCII PF03795.14 EAQ85734.1 - 6.7e-09 36.0 0.0 7.7e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain UBA PF00627.31 EAQ85735.1 - 6.4e-05 22.8 0.7 0.00014 21.7 0.1 1.9 2 0 0 2 2 2 1 UBA/TS-N domain UBX PF00789.20 EAQ85735.1 - 0.0027 17.9 0.0 0.0073 16.5 0.0 1.8 1 0 0 1 1 1 1 UBX domain ArAE_2 PF10334.9 EAQ85735.1 - 0.0042 16.9 0.1 0.0042 16.9 0.1 1.7 2 0 0 2 2 2 1 Aromatic acid exporter family member 2 NOZZLE PF08744.10 EAQ85735.1 - 0.083 12.4 2.7 0.13 11.7 2.7 1.2 1 0 0 1 1 1 0 Plant transcription factor NOZZLE DUF572 PF04502.13 EAQ85735.1 - 0.1 12.2 18.0 0.13 11.9 18.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) DAAD PF18752.1 EAQ85735.1 - 0.38 10.5 5.5 0.51 10.1 5.4 1.3 1 1 0 1 1 1 0 Dictyosteliid AID/APOBEC-like Deaminase CDC45 PF02724.14 EAQ85735.1 - 0.93 7.7 14.9 1.1 7.5 14.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Ku_C PF03730.14 EAQ85735.1 - 6.8 7.5 21.8 2.1e+02 2.7 19.8 3.3 2 1 1 3 3 3 0 Ku70/Ku80 C-terminal arm V_ATPase_I PF01496.19 EAQ85735.1 - 8.7 4.1 8.9 9 4.1 8.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Motile_Sperm PF00635.26 EAQ85736.1 - 1.5e-10 40.9 0.1 2.7e-10 40.1 0.1 1.4 1 0 0 1 1 1 1 MSP (Major sperm protein) domain zf-CCHC_6 PF15288.6 EAQ85736.1 - 1.6e-05 24.6 1.7 5.1e-05 23.0 1.7 1.8 1 0 0 1 1 1 1 Zinc knuckle AMP-binding PF00501.28 EAQ85737.1 - 3e-69 233.7 2.9 6.1e-45 153.6 0.1 2.1 1 1 1 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 EAQ85737.1 - 1.5e-19 70.7 0.6 3.1e-19 69.7 0.6 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GH3 PF03321.13 EAQ85737.1 - 0.00045 19.2 0.0 0.0023 16.9 0.0 1.9 2 0 0 2 2 2 1 GH3 auxin-responsive promoter RTX_C PF08339.10 EAQ85737.1 - 0.044 13.8 0.0 0.091 12.8 0.0 1.4 1 0 0 1 1 1 0 RTX C-terminal domain HA2 PF04408.23 EAQ85738.1 - 4.5e-18 65.5 0.1 4.5e-18 65.5 0.1 3.0 3 0 0 3 3 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EAQ85738.1 - 9.3e-18 64.4 0.0 2e-17 63.3 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EAQ85738.1 - 1.4e-12 47.9 0.0 3.5e-12 46.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EAQ85738.1 - 3.7e-06 26.8 0.1 8.9e-06 25.6 0.1 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAQ85738.1 - 0.00014 22.2 0.0 0.00047 20.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 EAQ85738.1 - 0.0035 17.0 0.1 0.0069 16.0 0.1 1.5 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_30 PF13604.6 EAQ85738.1 - 0.0046 16.7 0.1 0.0046 16.7 0.1 1.7 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EAQ85738.1 - 0.0052 17.1 0.2 0.012 15.9 0.2 1.6 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 EAQ85738.1 - 0.015 14.3 0.0 0.033 13.3 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein cobW PF02492.19 EAQ85738.1 - 0.04 13.5 0.1 2.9 7.4 0.1 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 EAQ85738.1 - 0.18 11.3 0.0 0.38 10.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region G-patch PF01585.23 EAQ85739.1 - 4.1e-11 42.6 0.7 1.2e-10 41.1 0.7 1.8 1 0 0 1 1 1 1 G-patch domain Ecm33 PF12454.8 EAQ85740.1 - 2.4e-14 53.2 3.8 6.5e-14 51.8 1.6 2.7 3 0 0 3 3 3 1 GPI-anchored cell wall organization protein Recep_L_domain PF01030.24 EAQ85740.1 - 6.9e-09 35.8 0.1 0.0049 17.0 0.0 3.8 2 1 1 3 3 3 2 Receptor L domain LRR_9 PF14580.6 EAQ85740.1 - 0.076 12.5 1.0 0.16 11.5 1.0 1.5 1 0 0 1 1 1 0 Leucine-rich repeat HhH-GPD PF00730.25 EAQ85741.1 - 3e-14 53.4 0.0 8.6e-14 51.9 0.0 1.7 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein DUF1484 PF07363.11 EAQ85741.1 - 2.3 9.2 4.6 3.8 8.6 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1484) Dscam_C PF12355.8 EAQ85741.1 - 5.9 7.9 7.3 6.3 7.8 0.2 2.4 2 0 0 2 2 2 0 Down syndrome cell adhesion molecule C terminal Anp1 PF03452.14 EAQ85742.1 - 1e-109 366.0 0.0 1.2e-109 365.8 0.0 1.1 1 0 0 1 1 1 1 Anp1 UCR_14kD PF02271.16 EAQ85743.1 - 1.2e-41 140.8 0.2 1.4e-41 140.5 0.2 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Mito_carr PF00153.27 EAQ85744.1 - 2.2e-27 94.8 0.6 8e-20 70.6 0.0 2.2 2 0 0 2 2 2 2 Mitochondrial carrier protein SWIRM-assoc_2 PF16496.5 EAQ85746.1 - 0.013 14.4 0.6 0.013 14.4 0.6 1.1 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal RNA_pol_Rpc4 PF05132.14 EAQ85746.1 - 0.071 13.5 0.8 0.074 13.5 0.8 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF2561 PF10812.8 EAQ85746.1 - 0.072 13.1 0.8 0.076 13.0 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) Stm1_N PF09598.10 EAQ85746.1 - 4.4 8.2 11.2 7.3 7.5 11.2 1.4 1 0 0 1 1 1 0 Stm1 TraF PF13728.6 EAQ85746.1 - 5.6 6.7 6.2 6.5 6.5 6.2 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein CI-B14_5a PF07347.12 EAQ85747.1 - 0.072 13.0 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) adh_short_C2 PF13561.6 EAQ85748.1 - 1e-47 162.7 2.3 6.8e-43 146.9 0.3 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EAQ85748.1 - 2.9e-44 150.9 0.3 3.7e-44 150.5 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EAQ85748.1 - 9.1e-16 58.3 0.2 1.2e-15 57.9 0.2 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EAQ85748.1 - 5.4e-07 29.3 0.2 3.3e-06 26.7 0.2 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 EAQ85748.1 - 0.026 13.9 0.0 0.038 13.4 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) DsbC_N PF10411.9 EAQ85748.1 - 0.072 12.6 0.0 1.3 8.5 0.0 2.5 2 0 0 2 2 2 0 Disulfide bond isomerase protein N-terminus HPP PF04982.13 EAQ85748.1 - 0.13 12.4 0.3 0.13 12.4 0.3 2.2 3 0 0 3 3 3 0 HPP family Acetyltransf_1 PF00583.25 EAQ85749.1 - 0.0021 18.3 0.0 0.0091 16.2 0.0 1.9 1 1 1 2 2 2 1 Acetyltransferase (GNAT) family FR47 PF08445.10 EAQ85749.1 - 0.0086 16.0 0.0 0.014 15.4 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein DUF4646 PF15496.6 EAQ85750.1 - 0.00029 21.5 0.0 0.36 11.5 0.0 2.8 2 0 0 2 2 2 2 Domain of unknown function (DUF4646) IF-2B PF01008.17 EAQ85751.1 - 1.4e-37 129.4 0.0 3.7e-37 128.1 0.0 1.6 1 1 0 1 1 1 1 Initiation factor 2 subunit family Ribosomal_L7Ae PF01248.26 EAQ85752.1 - 3.2e-15 55.6 0.4 4.3e-14 52.0 0.4 2.6 1 1 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family NPR3 PF03666.13 EAQ85752.1 - 0.98 8.1 5.9 1.3 7.7 5.9 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF1761 PF08570.10 EAQ85753.1 - 3.2e-26 92.0 4.9 3.7e-26 91.8 4.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1761) NIF PF03031.18 EAQ85754.1 - 2.3e-54 183.4 0.0 3.4e-54 182.9 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Calici_coat PF00915.20 EAQ85754.1 - 0.14 11.0 0.0 0.23 10.3 0.0 1.2 1 0 0 1 1 1 0 Calicivirus coat protein SEEEED PF14797.6 EAQ85754.1 - 9.6 6.4 13.9 18 5.5 13.9 1.4 1 0 0 1 1 1 0 Serine-rich region of AP3B1, clathrin-adaptor complex Band_7 PF01145.25 EAQ85755.1 - 2.5e-23 83.0 6.6 5.1e-23 82.0 6.6 1.5 1 1 0 1 1 1 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 EAQ85755.1 - 8.3e-05 21.8 5.3 0.00011 21.4 5.3 1.2 1 0 0 1 1 1 1 SigmaW regulon antibacterial Glyco_transf_8 PF01501.20 EAQ85757.1 - 1.4e-14 54.3 0.0 2.6e-14 53.4 0.0 1.4 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 EAQ85757.1 - 0.07 12.5 0.0 0.24 10.7 0.0 1.8 2 0 0 2 2 2 0 Mannosyltransferase putative Glyco_transf_24 PF18404.1 EAQ85757.1 - 0.14 11.5 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 Glucosyltransferase 24 UCH PF00443.29 EAQ85758.1 - 4.4e-34 118.1 0.0 1.4e-33 116.5 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EAQ85758.1 - 1.4e-07 31.5 0.0 6.2e-07 29.3 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase SAE2 PF08573.10 EAQ85759.1 - 2.4e-36 125.2 2.7 6.3e-36 123.9 0.0 2.9 2 1 0 2 2 2 1 DNA repair protein endonuclease SAE2/CtIP C-terminus bZIP_1 PF00170.21 EAQ85759.1 - 0.061 13.4 0.3 0.061 13.4 0.3 3.3 2 1 0 2 2 2 0 bZIP transcription factor DUF2205 PF10224.9 EAQ85759.1 - 0.1 12.6 1.6 0.49 10.4 1.6 2.2 1 0 0 1 1 1 0 Short coiled-coil protein Shugoshin_N PF07558.11 EAQ85759.1 - 0.71 9.8 4.0 0.78 9.7 0.9 2.5 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region DUF3450 PF11932.8 EAQ85759.1 - 1.4 8.1 12.8 2.6 7.3 3.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) KIAA1430 PF13879.6 EAQ85759.1 - 1.6 9.5 6.9 0.096 13.5 0.6 2.3 3 0 0 3 3 3 0 KIAA1430 homologue SKA2 PF16740.5 EAQ85759.1 - 4.1 7.2 8.0 0.63 9.8 2.4 2.2 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 YabA PF06156.13 EAQ85759.1 - 4.2 8.1 6.5 59 4.4 6.5 2.5 1 1 0 1 1 1 0 Initiation control protein YabA zf-CCHC PF00098.23 EAQ85760.1 - 5.2e-48 159.1 59.0 9.5e-09 34.9 4.3 7.3 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.6 EAQ85760.1 - 1.5e-11 43.8 35.3 0.0023 17.6 1.0 6.2 6 0 0 6 6 6 6 Zinc knuckle zf-CCHC_3 PF13917.6 EAQ85760.1 - 3.9e-08 33.1 36.4 0.12 12.3 0.8 6.3 3 2 3 6 6 6 5 Zinc knuckle zf-CCHC_5 PF14787.6 EAQ85760.1 - 0.02 14.6 39.7 2.7 7.8 0.5 7.1 5 2 2 7 7 7 0 GAG-polyprotein viral zinc-finger zf-CCHC_6 PF15288.6 EAQ85760.1 - 0.039 13.8 48.0 0.062 13.1 2.1 6.3 6 1 1 7 7 7 0 Zinc knuckle DUF2256 PF10013.9 EAQ85760.1 - 0.45 10.7 5.2 33 4.7 0.1 4.1 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) RMF PF04957.12 EAQ85760.1 - 2.2 8.6 7.6 18 5.6 1.3 3.0 2 1 1 3 3 3 0 Ribosome modulation factor Acyl-CoA_dh_1 PF00441.24 EAQ85761.1 - 6.6e-36 123.8 1.4 1e-35 123.2 1.4 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.28 EAQ85761.1 - 2.4e-18 66.0 0.0 7.2e-18 64.5 0.0 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.19 EAQ85761.1 - 1.1e-15 57.5 0.2 2.2e-15 56.6 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 EAQ85761.1 - 2.1e-07 31.6 0.1 1.2e-06 29.2 0.0 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 EAQ85761.1 - 2.5e-05 24.6 0.2 5.4e-05 23.5 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Amino_oxidase PF01593.24 EAQ85762.1 - 4.2e-44 151.6 0.1 1.7e-43 149.5 0.1 1.8 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EAQ85762.1 - 2.3e-16 59.8 0.0 5.3e-16 58.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EAQ85762.1 - 2.8e-07 30.7 0.1 0.00038 20.5 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 EAQ85762.1 - 5.7e-07 29.1 0.0 9.4e-05 21.8 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EAQ85762.1 - 2e-05 24.4 1.4 0.00045 19.9 1.4 2.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EAQ85762.1 - 7.3e-05 23.2 0.4 0.00029 21.3 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EAQ85762.1 - 0.00016 20.5 0.1 0.0028 16.4 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 EAQ85762.1 - 0.00078 18.8 0.0 0.0013 18.0 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 EAQ85762.1 - 0.0009 18.6 0.1 0.0014 17.9 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 EAQ85762.1 - 0.0012 18.0 0.1 0.0021 17.2 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 EAQ85762.1 - 0.0049 16.3 0.0 0.0072 15.7 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase 3HCDH_N PF02737.18 EAQ85762.1 - 0.02 14.8 0.1 0.04 13.8 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 EAQ85762.1 - 0.12 11.7 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Rossmann-like PF10727.9 EAQ85762.1 - 0.12 12.3 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 Rossmann-like domain Pyr_redox_3 PF13738.6 EAQ85762.1 - 0.21 10.8 0.4 0.41 9.8 0.1 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ATG2_CAD PF13329.6 EAQ85763.1 - 3.7e-50 169.7 0.2 1e-49 168.3 0.2 1.8 1 0 0 1 1 1 1 Autophagy-related protein 2 CAD motif ATG_C PF09333.11 EAQ85763.1 - 1.3e-31 108.8 1.6 8.2e-31 106.2 0.1 3.1 3 0 0 3 3 3 1 Autophagy-related protein C terminal domain Chorein_N PF12624.7 EAQ85763.1 - 4.2e-05 23.6 0.0 0.00011 22.3 0.0 1.7 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 VPS13 PF16908.5 EAQ85763.1 - 0.096 12.5 0.0 1.1 9.0 0.0 2.2 2 0 0 2 2 2 0 Vacuolar sorting-associated protein 13, N-terminal VPS13_C PF16909.5 EAQ85763.1 - 0.14 11.9 0.0 0.48 10.2 0.0 1.9 2 0 0 2 2 2 0 Vacuolar-sorting-associated 13 protein C-terminal zf-UBR PF02207.20 EAQ85764.1 - 2.3e-13 50.1 3.4 2.3e-13 50.1 3.4 3.0 4 0 0 4 4 4 1 Putative zinc finger in N-recognin (UBR box) FancD2 PF14631.6 EAQ85764.1 - 0.074 10.5 0.8 0.1 10.0 0.8 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease ROKNT PF08067.11 EAQ85764.1 - 2.1 8.7 7.4 0.22 11.8 1.4 2.4 2 0 0 2 2 2 0 ROKNT (NUC014) domain MCM PF00493.23 EAQ85765.1 - 9.3e-81 270.2 3.1 5.1e-79 264.5 0.0 2.9 2 1 1 3 3 3 2 MCM P-loop domain MCM_OB PF17207.3 EAQ85765.1 - 1.3e-38 131.6 0.1 2.6e-38 130.7 0.1 1.4 1 0 0 1 1 1 1 MCM OB domain MCM2_N PF12619.8 EAQ85765.1 - 1.6e-31 109.7 35.4 1.6e-31 109.7 35.4 2.2 3 0 0 3 3 3 1 Mini-chromosome maintenance protein 2 MCM_lid PF17855.1 EAQ85765.1 - 5.7e-26 90.8 0.6 1.5e-25 89.4 0.6 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EAQ85765.1 - 2.4e-14 53.8 0.1 5.9e-14 52.5 0.1 1.6 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 EAQ85765.1 - 2.7e-07 30.2 0.0 5.8e-06 25.8 0.0 2.4 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EAQ85765.1 - 1.9e-06 27.9 0.0 4.4e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 EAQ85765.1 - 0.00017 21.4 0.1 0.0013 18.5 0.1 2.1 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.11 EAQ85765.1 - 0.0019 18.0 0.1 0.014 15.3 0.0 2.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.6 EAQ85765.1 - 0.1 12.7 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain HAD_2 PF13419.6 EAQ85766.1 - 2.4e-05 24.5 0.0 3.9e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase DUF913 PF06025.12 EAQ85766.1 - 0.18 10.8 0.0 0.25 10.3 0.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Ribosomal_L5e PF17144.4 EAQ85767.1 - 1.5e-79 265.6 0.2 2.7e-79 264.8 0.2 1.4 1 0 0 1 1 1 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 EAQ85767.1 - 2.7e-34 118.0 8.7 2.7e-34 118.0 8.7 1.9 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region LRR_6 PF13516.6 EAQ85768.1 - 4.7e-05 23.1 14.8 23 5.4 0.1 7.9 8 0 0 8 8 8 5 Leucine Rich repeat Transposase_28 PF04195.12 EAQ85768.1 - 0.14 12.4 0.0 0.33 11.2 0.0 1.5 1 0 0 1 1 1 0 Putative gypsy type transposon TFIIA PF03153.13 EAQ85769.1 - 9.6e-05 22.5 12.5 0.00014 22.0 12.5 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF4763 PF15960.5 EAQ85769.1 - 0.017 14.4 0.0 0.017 14.4 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4763) DUF5327 PF17261.2 EAQ85769.1 - 5.7 7.8 14.7 71 4.2 11.4 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5327) Med1 PF10744.9 EAQ85770.1 - 6.1e-113 378.0 0.0 8.3e-113 377.6 0.0 1.2 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 Neogenin_C PF06583.12 EAQ85770.1 - 5 6.9 7.2 9.5 6.0 7.2 1.4 1 0 0 1 1 1 0 Neogenin C-terminus Pkinase PF00069.25 EAQ85771.1 - 1.7e-41 142.3 0.0 5.2e-39 134.2 0.0 2.8 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ85771.1 - 2.5e-22 79.4 0.0 4.8e-22 78.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase MRC1 PF09444.10 EAQ85772.1 - 2.2e-43 148.2 24.0 2.2e-43 148.2 24.0 7.2 5 3 1 7 7 7 1 MRC1-like domain DIRP PF06584.13 EAQ85772.1 - 0.05 13.8 0.2 0.05 13.8 0.2 2.4 2 0 0 2 2 2 0 DIRP Ribosomal_S8e PF01201.22 EAQ85772.1 - 0.095 12.9 2.7 2.1 8.5 0.5 2.9 2 0 0 2 2 2 0 Ribosomal protein S8e SAGA-Tad1 PF12767.7 EAQ85773.1 - 1.8e-34 119.5 0.0 2.4e-34 119.1 0.0 1.1 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit GCP_C_terminal PF04130.13 EAQ85774.1 - 6.5e-75 252.5 0.0 1e-74 251.8 0.0 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 EAQ85774.1 - 1.5e-59 202.2 0.0 3.8e-59 200.8 0.0 1.6 1 1 1 2 2 2 1 Gamma tubulin complex component N-terminal Amidohydro_2 PF04909.14 EAQ85775.1 - 2.7e-07 30.7 0.0 6.3e-06 26.2 0.0 2.1 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_1 PF01979.20 EAQ85775.1 - 0.0071 15.7 0.0 0.021 14.2 0.0 1.9 1 1 0 1 1 1 1 Amidohydrolase family ZnuA PF01297.17 EAQ85775.1 - 0.19 11.1 0.0 11 5.3 0.0 2.3 2 0 0 2 2 2 0 Zinc-uptake complex component A periplasmic MFS_1 PF07690.16 EAQ85776.1 - 2.9e-17 62.6 53.6 4.4e-15 55.5 53.6 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF5336 PF17270.2 EAQ85777.1 - 6.2e-05 22.7 0.7 0.00048 19.8 0.7 2.6 1 0 0 1 1 1 1 Family of unknown function (DUF5336) DUF3995 PF13160.6 EAQ85777.1 - 0.25 11.7 16.0 0.36 11.2 2.1 4.2 3 2 1 4 4 4 0 Protein of unknown function (DUF3995) Fungal_trans PF04082.18 EAQ85778.1 - 4.3e-22 78.4 0.0 7.3e-22 77.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EAQ85778.1 - 6.1e-06 26.3 15.4 1.1e-05 25.5 15.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4166 PF13761.6 EAQ85780.1 - 0.024 14.4 0.0 0.039 13.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4166) DHquinase_I PF01487.15 EAQ85781.1 - 4.9e-32 112.0 0.0 7.5e-32 111.4 0.0 1.2 1 0 0 1 1 1 1 Type I 3-dehydroquinase DHO_dh PF01180.21 EAQ85782.1 - 2.4e-17 63.1 0.0 2e-15 56.8 0.0 2.7 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase RNA_Me_trans PF04252.13 EAQ85783.1 - 1.1e-84 283.1 0.0 1.2e-84 282.9 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase Peptidase_S10 PF00450.22 EAQ85784.1 - 3.9e-114 382.3 0.0 4.9e-114 382.0 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase CIAPIN1 PF05093.13 EAQ85785.1 - 2.4e-42 143.5 4.4 3.8e-42 142.9 4.4 1.3 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DRE2_N PF16803.5 EAQ85785.1 - 5.8e-34 117.2 0.0 8.6e-34 116.6 0.0 1.3 1 0 0 1 1 1 1 Fe-S cluster assembly protein DRE2 N-terminus HABP4_PAI-RBP1 PF04774.15 EAQ85786.1 - 0.07 14.0 3.8 0.12 13.3 3.8 1.3 1 1 0 1 1 1 0 Hyaluronan / mRNA binding family Formyl_trans_N PF00551.19 EAQ85787.1 - 3.9e-10 39.8 0.0 6.7e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Formyl transferase Pex19 PF04614.12 EAQ85789.1 - 2.7e-75 253.3 11.2 2.7e-75 253.3 11.2 1.9 2 0 0 2 2 2 1 Pex19 protein family ATG_C PF09333.11 EAQ85789.1 - 0.029 14.7 0.1 0.07 13.5 0.1 1.6 1 0 0 1 1 1 0 Autophagy-related protein C terminal domain GET2 PF08690.10 EAQ85789.1 - 0.49 10.0 13.4 0.038 13.7 7.5 2.0 1 1 2 3 3 3 0 GET complex subunit GET2 FKBP_N PF01346.18 EAQ85789.1 - 1.9 9.5 9.5 11 7.1 4.3 3.2 1 1 1 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase FliE PF02049.18 EAQ85789.1 - 6.6 7.0 12.0 0.81 9.9 3.0 3.4 2 1 1 3 3 3 0 Flagellar hook-basal body complex protein FliE TrbI PF03743.14 EAQ85789.1 - 6.7 6.5 7.3 18 5.1 7.4 1.7 1 1 0 1 1 1 0 Bacterial conjugation TrbI-like protein UQ_con PF00179.26 EAQ85790.1 - 5.4e-49 165.4 0.1 6.1e-49 165.3 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EAQ85790.1 - 0.00015 21.5 0.0 0.00018 21.2 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 EAQ85790.1 - 0.038 14.3 1.1 0.085 13.1 1.1 1.8 1 1 0 1 1 1 0 RWD domain Asn_synthase PF00733.21 EAQ85791.1 - 1.5e-92 311.0 0.1 2.6e-54 185.2 0.0 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 EAQ85791.1 - 4.7e-37 126.7 0.0 8.1e-37 125.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 EAQ85791.1 - 8.3e-28 97.2 0.0 1.6e-27 96.4 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 EAQ85791.1 - 1.3e-07 31.3 0.0 2.4e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 EAQ85791.1 - 0.001 18.3 0.0 0.0035 16.5 0.0 1.8 1 1 0 1 1 1 1 NAD synthase Porin_3 PF01459.22 EAQ85792.1 - 1.3e-73 247.8 10.7 1.5e-73 247.6 10.7 1.0 1 0 0 1 1 1 1 Eukaryotic porin Peptidase_M24 PF00557.24 EAQ85793.1 - 4.4e-44 150.7 0.0 5.8e-44 150.3 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF3323 PF11796.8 EAQ85793.1 - 0.11 12.3 0.2 0.18 11.6 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function N-terminus (DUF3323) SPT6_acidic PF14632.6 EAQ85793.1 - 6.8 7.4 10.7 15 6.3 10.7 1.6 1 1 0 1 1 1 0 Acidic N-terminal SPT6 PRELI PF04707.14 EAQ85794.1 - 5.6e-42 143.2 0.2 6.9e-42 142.9 0.2 1.1 1 0 0 1 1 1 1 PRELI-like family DUF3618 PF12277.8 EAQ85797.1 - 0.16 12.2 3.6 0.4 11.0 3.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3618) ABC1 PF03109.16 EAQ85799.1 - 4.7e-32 110.7 0.0 7.8e-32 109.9 0.0 1.4 1 0 0 1 1 1 1 ABC1 family 2OG-FeII_Oxy_3 PF13640.6 EAQ85800.1 - 5e-07 30.5 0.0 7.2e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Glyco_hydro_76 PF03663.14 EAQ85802.1 - 1.7e-105 353.6 12.9 1.3e-83 281.6 8.6 2.1 2 0 0 2 2 2 2 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 EAQ85802.1 - 0.18 10.9 4.6 0.68 9.0 0.2 2.4 2 1 1 3 3 3 0 Glycosyl Hydrolase Family 88 Gln-synt_C PF00120.24 EAQ85803.1 - 3e-77 259.9 0.0 4.6e-77 259.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Amidohydro_2 PF04909.14 EAQ85803.1 - 1.1e-15 58.2 0.8 5.4e-15 55.9 0.0 2.4 3 0 0 3 3 3 1 Amidohydrolase ERGIC_N PF13850.6 EAQ85804.1 - 4.9e-25 87.7 0.0 8.1e-25 87.0 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) COPIIcoated_ERV PF07970.12 EAQ85804.1 - 2.3e-16 60.3 0.0 3.1e-16 59.9 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter AAT PF03417.16 EAQ85805.1 - 1.6e-15 57.5 0.0 2.3e-15 56.9 0.0 1.2 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase DUF733 PF05306.11 EAQ85805.1 - 0.071 13.4 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF733) Prok-E2_E PF14462.6 EAQ85805.1 - 0.15 11.9 0.1 0.6 9.9 0.2 1.8 2 0 0 2 2 2 0 Prokaryotic E2 family E WD40 PF00400.32 EAQ85807.1 - 1.1e-16 60.9 3.5 0.0065 17.3 0.7 5.9 6 1 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAQ85807.1 - 1e-05 25.7 0.0 0.013 15.8 0.0 4.3 1 1 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EAQ85807.1 - 0.0086 15.4 0.0 0.02 14.2 0.0 1.6 1 1 0 1 1 1 1 WD40-like domain CTP_transf_like PF01467.26 EAQ85808.1 - 6.6e-25 88.0 0.0 4.2e-20 72.4 0.0 3.3 2 1 0 3 3 3 3 Cytidylyltransferase-like Aminotran_4 PF01063.19 EAQ85811.1 - 8.8e-24 84.6 0.0 1.1e-23 84.3 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV AhpC-TSA_2 PF13911.6 EAQ85812.1 - 1.5e-08 34.7 0.0 3e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AAA_12 PF13087.6 EAQ85813.1 - 2.8e-61 206.6 0.0 7.2e-61 205.3 0.0 1.7 2 0 0 2 2 2 1 AAA domain UPF1_Zn_bind PF09416.10 EAQ85813.1 - 9.3e-56 188.0 0.4 1.5e-54 184.2 0.1 2.3 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_11 PF13086.6 EAQ85813.1 - 5.7e-54 183.6 3.5 1.2e-30 107.2 0.2 2.3 1 1 1 2 2 2 2 AAA domain DUF5599 PF18141.1 EAQ85813.1 - 1.6e-33 114.8 0.0 3.1e-33 113.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5599) AAA_30 PF13604.6 EAQ85813.1 - 8.1e-13 48.5 0.3 1.6e-11 44.3 0.3 2.3 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAQ85813.1 - 1.5e-10 41.6 0.1 6.4e-10 39.5 0.1 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAQ85813.1 - 5e-06 26.6 0.0 1e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 EAQ85813.1 - 2.9e-05 23.9 0.1 0.28 10.9 0.0 3.0 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.14 EAQ85813.1 - 0.00013 21.8 0.6 0.00028 20.8 0.1 2.0 2 0 0 2 2 1 1 Helicase DUF2075 PF09848.9 EAQ85813.1 - 0.00015 21.1 0.2 0.005 16.1 0.0 2.4 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) UvrD-helicase PF00580.21 EAQ85813.1 - 0.00044 19.9 0.1 0.01 15.4 0.1 2.2 1 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain PIF1 PF05970.14 EAQ85813.1 - 0.0005 19.3 0.3 0.24 10.6 0.1 2.3 1 1 0 2 2 2 2 PIF1-like helicase DEAD PF00270.29 EAQ85813.1 - 0.0029 17.4 0.1 0.0058 16.4 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ATPase PF06745.13 EAQ85813.1 - 0.016 14.5 0.0 0.049 13.0 0.0 1.7 2 0 0 2 2 2 0 KaiC AAA_10 PF12846.7 EAQ85813.1 - 0.018 14.0 0.0 0.028 13.3 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain SRP54 PF00448.22 EAQ85813.1 - 0.023 14.3 0.0 0.05 13.2 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_22 PF13401.6 EAQ85813.1 - 0.029 14.7 0.0 0.11 12.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 EAQ85813.1 - 0.075 12.5 0.0 0.22 10.9 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein AAA_5 PF07728.14 EAQ85813.1 - 0.15 12.1 0.0 0.34 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Brix PF04427.18 EAQ85814.1 - 7.1e-29 101.3 0.2 8.9e-29 101.0 0.2 1.1 1 0 0 1 1 1 1 Brix domain Syntaxin PF00804.25 EAQ85815.1 - 1.2e-13 51.2 6.2 1.2e-13 51.2 6.2 1.6 1 1 1 2 2 2 1 Syntaxin Exonuc_VII_L PF02601.15 EAQ85815.1 - 0.053 13.1 6.8 0.071 12.7 6.8 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit bZIP_1 PF00170.21 EAQ85815.1 - 0.16 12.1 1.8 3 8.0 0.1 2.5 2 0 0 2 2 2 0 bZIP transcription factor DUF3018 PF11455.8 EAQ85815.1 - 0.19 11.7 2.7 0.62 10.0 0.4 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3018) TPR_1 PF00515.28 EAQ85816.1 - 1.1e-41 139.0 19.1 1.6e-07 30.8 0.0 10.1 9 1 1 10 10 10 9 Tetratricopeptide repeat TPR_2 PF07719.17 EAQ85816.1 - 1.2e-39 131.2 17.3 4.4e-06 26.4 0.0 10.4 9 1 1 10 10 10 9 Tetratricopeptide repeat TPR_8 PF13181.6 EAQ85816.1 - 6.5e-21 72.8 18.6 2.9e-05 23.9 0.0 9.6 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_16 PF13432.6 EAQ85816.1 - 3e-20 72.6 12.4 1.6e-06 28.7 0.0 7.7 7 1 1 8 8 8 5 Tetratricopeptide repeat TPR_17 PF13431.6 EAQ85816.1 - 1.6e-17 62.5 9.9 0.011 16.1 0.0 7.7 7 2 0 7 7 7 4 Tetratricopeptide repeat TPR_11 PF13414.6 EAQ85816.1 - 9.4e-17 60.4 21.5 3.3e-06 26.7 0.0 8.0 6 2 1 7 7 7 3 TPR repeat TPR_14 PF13428.6 EAQ85816.1 - 7.9e-16 57.4 14.3 0.0008 20.0 0.1 8.9 6 3 2 9 9 8 3 Tetratricopeptide repeat TPR_12 PF13424.6 EAQ85816.1 - 3.9e-15 55.9 24.5 0.00099 19.4 0.9 9.0 3 2 5 8 8 8 5 Tetratricopeptide repeat TPR_19 PF14559.6 EAQ85816.1 - 2.6e-14 53.5 14.7 2e-05 25.0 1.2 6.3 5 2 3 8 8 7 2 Tetratricopeptide repeat TPR_9 PF13371.6 EAQ85816.1 - 4.7e-14 52.3 6.2 0.0018 18.4 0.0 6.0 5 2 3 8 8 7 4 Tetratricopeptide repeat TPR_7 PF13176.6 EAQ85816.1 - 3e-08 33.1 21.3 0.031 14.3 0.3 8.8 9 0 0 9 9 9 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EAQ85816.1 - 4.9e-07 29.9 15.4 0.042 14.1 0.2 4.9 4 1 1 5 5 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_MalT PF17874.1 EAQ85816.1 - 7.5e-07 28.8 0.6 3.9e-06 26.5 0.6 2.0 1 1 0 1 1 1 1 MalT-like TPR region TPR_15 PF13429.6 EAQ85816.1 - 1.5e-06 27.7 5.1 0.033 13.4 0.4 4.6 2 1 2 4 4 4 2 Tetratricopeptide repeat DUF3856 PF12968.7 EAQ85816.1 - 0.00015 21.9 4.3 2.5 8.2 0.0 5.0 4 2 0 4 4 4 2 Domain of Unknown Function (DUF3856) TPR_10 PF13374.6 EAQ85816.1 - 0.00018 21.3 22.3 0.032 14.1 0.5 7.2 9 0 0 9 9 7 2 Tetratricopeptide repeat SHNi-TPR PF10516.9 EAQ85816.1 - 0.00021 20.7 7.6 0.29 10.6 0.0 5.1 6 0 0 6 6 5 2 SHNi-TPR BTAD PF03704.17 EAQ85816.1 - 0.0012 19.3 1.7 23 5.4 0.1 5.0 3 3 1 5 5 5 0 Bacterial transcriptional activator domain MAS20 PF02064.15 EAQ85816.1 - 0.007 16.5 4.1 3.3 7.8 0.2 4.0 3 1 1 4 4 4 1 MAS20 protein import receptor TPR_6 PF13174.6 EAQ85816.1 - 0.012 16.2 18.3 12 6.7 0.7 9.0 9 0 0 9 9 9 0 Tetratricopeptide repeat NYD-SP12_N PF15015.6 EAQ85816.1 - 0.04 12.3 0.3 0.099 11.0 0.3 1.5 1 1 0 1 1 1 0 Spermatogenesis-associated, N-terminal TAF1_subA PF14929.6 EAQ85816.1 - 0.051 13.0 0.4 0.12 11.7 0.2 1.6 1 1 0 1 1 1 0 TAF RNA Polymerase I subunit A TPR_20 PF14561.6 EAQ85816.1 - 0.059 13.7 5.2 2.6 8.4 0.1 3.9 3 1 0 3 3 3 0 Tetratricopeptide repeat preATP-grasp_3 PF18301.1 EAQ85816.1 - 0.11 12.8 0.1 0.39 11.0 0.1 2.0 1 0 0 1 1 1 0 pre ATP-grasp 3 domain NARP1 PF12569.8 EAQ85816.1 - 0.11 11.4 13.7 1.4 7.7 1.5 4.0 3 1 0 3 3 3 0 NMDA receptor-regulated protein 1 MIT PF04212.18 EAQ85816.1 - 0.26 11.4 14.7 13 6.0 0.3 6.8 7 0 0 7 7 7 0 MIT (microtubule interacting and transport) domain Sel1 PF08238.12 EAQ85816.1 - 0.43 11.3 7.4 1.7 9.5 0.1 4.0 4 0 0 4 4 3 0 Sel1 repeat HemY_N PF07219.13 EAQ85816.1 - 0.57 10.4 8.6 37 4.6 1.4 5.1 6 1 1 7 7 5 0 HemY protein N-terminus PSD5 PF07637.11 EAQ85816.1 - 1.3 9.5 3.9 1.9 8.9 0.0 3.2 4 0 0 4 4 3 0 Protein of unknown function (DUF1595) Asp PF00026.23 EAQ85817.1 - 8.4e-55 186.4 2.1 1.7e-54 185.4 2.1 1.4 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Aminotran_4 PF01063.19 EAQ85817.1 - 2.3e-16 60.3 0.0 4.1e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 Amino-transferase class IV TAXi_N PF14543.6 EAQ85817.1 - 2.4e-07 31.2 1.1 0.0021 18.3 0.2 2.5 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EAQ85817.1 - 0.0058 17.2 0.2 2.9 8.6 0.2 2.6 2 0 0 2 2 2 2 Aspartyl protease Btz PF09405.10 EAQ85818.1 - 1.7e-29 102.7 0.6 1.7e-29 102.7 0.6 2.1 2 0 0 2 2 2 1 CASC3/Barentsz eIF4AIII binding DUF5473 PF17567.2 EAQ85818.1 - 0.11 12.8 1.4 0.55 10.5 0.2 2.6 3 0 0 3 3 3 0 Family of unknown function (DUF5473) UPF0052 PF01933.18 EAQ85819.1 - 1.8e-35 122.6 0.0 3.8e-35 121.5 0.0 1.5 1 1 0 1 1 1 1 Uncharacterised protein family UPF0052 N_BRCA1_IG PF16158.5 EAQ85820.1 - 1.9e-32 112.0 0.0 4.1e-32 110.9 0.0 1.6 1 0 0 1 1 1 1 Ig-like domain from next to BRCA1 gene ZZ PF00569.17 EAQ85820.1 - 5.7e-18 64.5 58.2 8.3e-06 25.5 5.2 4.5 4 0 0 4 4 4 4 Zinc finger, ZZ type C1_2 PF03107.16 EAQ85820.1 - 0.93 9.9 53.8 0.19 12.1 12.1 4.9 4 0 0 4 4 4 0 C1 domain RRM_1 PF00076.22 EAQ85821.1 - 5.9e-18 64.4 0.1 1.1e-12 47.6 0.0 3.6 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EAQ85821.1 - 0.043 13.8 0.0 0.11 12.5 0.0 1.7 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 EAQ85821.1 - 0.045 13.9 0.1 0.21 11.7 0.1 2.2 2 0 0 2 2 2 0 RNA recognition motif Cut8 PF08559.10 EAQ85822.1 - 1.3e-74 250.8 0.0 1.8e-74 250.4 0.0 1.0 1 0 0 1 1 1 1 Cut8, nuclear proteasome tether protein Rad52_Rad22 PF04098.15 EAQ85823.1 - 7.8e-58 194.7 0.0 1.1e-57 194.3 0.0 1.2 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein Calsequestrin PF01216.17 EAQ85823.1 - 0.18 10.8 0.4 0.27 10.2 0.4 1.2 1 0 0 1 1 1 0 Calsequestrin Aconitase PF00330.20 EAQ85824.1 - 1.2e-147 492.6 0.0 1.5e-147 492.3 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EAQ85824.1 - 2.6e-38 131.3 0.0 4.3e-38 130.6 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain APH PF01636.23 EAQ85825.1 - 1.9e-07 31.3 1.1 2.9e-07 30.7 1.1 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EAQ85825.1 - 0.00089 18.9 0.0 0.0013 18.4 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Cnd1 PF12717.7 EAQ85827.1 - 2.9e-08 33.9 0.0 6.9e-05 22.9 0.0 1.9 1 1 1 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EAQ85827.1 - 1.5e-06 28.0 0.8 0.069 13.4 0.0 4.9 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.6 EAQ85827.1 - 0.0058 17.0 0.1 0.16 12.4 0.0 3.1 2 1 1 4 4 4 2 HEAT repeats HEAT_EZ PF13513.6 EAQ85827.1 - 0.016 15.7 0.1 6.5 7.4 0.0 3.5 3 1 0 3 3 3 0 HEAT-like repeat Pkinase PF00069.25 EAQ85827.1 - 0.078 12.3 0.0 0.31 10.4 0.0 1.8 2 0 0 2 2 2 0 Protein kinase domain FtsH_ext PF06480.15 EAQ85827.1 - 1.6 9.1 4.3 3.3 8.1 0.4 3.0 3 0 0 3 3 3 0 FtsH Extracellular DUF3439 PF11921.8 EAQ85827.1 - 7.1 6.6 11.3 0.18 11.8 3.7 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3439) WD40 PF00400.32 EAQ85828.1 - 7.8e-41 137.3 19.4 9.9e-11 42.0 0.3 7.7 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAQ85828.1 - 1.4e-12 47.7 0.4 0.0029 17.9 0.0 5.0 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EAQ85828.1 - 5.8e-08 31.8 4.7 0.016 13.9 0.2 4.9 3 1 1 4 4 4 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EAQ85828.1 - 1.3e-07 30.9 0.6 0.22 10.5 0.0 4.2 1 1 3 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 EAQ85828.1 - 0.00028 19.3 0.0 0.00067 18.1 0.0 1.6 2 0 0 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz PALB2_WD40 PF16756.5 EAQ85828.1 - 0.0088 15.0 2.5 0.044 12.7 0.1 3.0 3 1 1 4 4 4 1 Partner and localizer of BRCA2 WD40 domain FHA PF00498.26 EAQ85830.1 - 2.2e-12 47.1 0.0 5e-12 46.0 0.0 1.7 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EAQ85830.1 - 0.066 13.5 0.1 0.22 11.9 0.0 2.0 2 0 0 2 2 2 0 Inner membrane component of T3SS, cytoplasmic domain CDC45 PF02724.14 EAQ85830.1 - 4.7 5.4 12.5 8 4.6 12.5 1.3 1 0 0 1 1 1 0 CDC45-like protein IFRD PF05004.13 EAQ85831.1 - 4e-80 269.2 6.4 5e-80 268.9 6.4 1.1 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) HEAT_2 PF13646.6 EAQ85831.1 - 0.0016 18.8 0.3 0.085 13.3 0.1 2.5 1 1 0 2 2 2 1 HEAT repeats FAA_hydro_N_2 PF18288.1 EAQ85831.1 - 0.0082 16.5 0.2 0.028 14.8 0.2 1.9 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal domain 2 Adaptin_N PF01602.20 EAQ85831.1 - 0.062 11.9 0.0 0.15 10.6 0.0 1.5 1 1 0 1 1 1 0 Adaptin N terminal region HEAT_EZ PF13513.6 EAQ85831.1 - 0.066 13.7 0.1 13 6.4 0.0 3.5 4 0 0 4 4 4 0 HEAT-like repeat UME PF08064.13 EAQ85831.1 - 0.2 11.6 0.5 3.2 7.7 0.0 2.7 2 1 1 3 3 3 0 UME (NUC010) domain GHMP_kinases_N PF00288.26 EAQ85834.1 - 2.2e-09 37.4 0.0 4.4e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EAQ85834.1 - 5.3e-06 26.7 0.0 1.3e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal Methyltransf_23 PF13489.6 EAQ85836.1 - 0.01 15.7 0.0 0.17 11.7 0.0 2.2 1 1 1 2 2 2 0 Methyltransferase domain Methyltransf_2 PF00891.18 EAQ85837.1 - 6.7e-12 45.1 0.0 1.1e-08 34.7 0.0 2.5 1 1 1 2 2 2 2 O-methyltransferase domain Actin PF00022.19 EAQ85838.1 - 3.3e-103 345.4 0.0 2.1e-67 227.5 0.0 2.7 1 1 1 2 2 2 2 Actin MreB_Mbl PF06723.13 EAQ85838.1 - 0.0037 16.1 0.1 0.19 10.5 0.1 2.8 1 1 0 1 1 1 1 MreB/Mbl protein DUF3602 PF12223.8 EAQ85839.1 - 4.6e-19 68.8 12.9 2.2e-18 66.6 5.3 2.5 2 1 1 3 3 3 2 Protein of unknown function (DUF3602) Chitin_synth_1 PF01644.17 EAQ85840.1 - 3e-74 248.4 0.2 4.1e-74 248.0 0.2 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.15 EAQ85840.1 - 7.3e-10 38.1 0.0 1.2e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Sec1 PF00995.23 EAQ85841.1 - 2.2e-94 317.7 0.0 8.4e-94 315.8 0.0 1.7 1 1 0 1 1 1 1 Sec1 family zf_CCCH_4 PF18345.1 EAQ85842.1 - 1.1e-05 25.3 5.3 2e-05 24.5 5.3 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 EAQ85842.1 - 5.5e-05 22.9 1.7 8.8e-05 22.2 1.7 1.3 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH PF00642.24 EAQ85842.1 - 0.0018 18.1 2.1 0.0036 17.2 2.1 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 EAQ85842.1 - 0.0021 18.7 0.3 0.0021 18.7 0.3 3.5 4 0 0 4 4 4 1 Torus domain zf-CCCH_2 PF14608.6 EAQ85842.1 - 0.0091 16.4 1.6 0.016 15.7 1.6 1.4 1 0 0 1 1 1 1 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 EAQ85842.1 - 0.025 14.8 0.4 0.068 13.4 0.4 1.8 1 0 0 1 1 1 0 Zinc-finger containing family Flavoprotein PF02441.19 EAQ85843.1 - 3.2e-12 46.5 0.0 2.9e-11 43.4 0.0 2.2 1 1 0 1 1 1 1 Flavoprotein Putative_PNPOx PF01243.20 EAQ85843.1 - 0.072 13.3 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase SHNi-TPR PF10516.9 EAQ85844.1 - 8e-16 57.2 0.1 4.4e-15 54.8 0.1 2.4 1 0 0 1 1 1 1 SHNi-TPR TPR_3 PF07720.12 EAQ85844.1 - 0.00016 21.6 3.8 0.0004 20.3 3.8 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.6 EAQ85844.1 - 0.00019 21.7 6.9 0.0009 19.5 0.4 3.3 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 EAQ85844.1 - 0.0012 19.5 12.3 0.0066 17.1 1.9 4.7 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 EAQ85844.1 - 0.013 15.8 0.3 0.15 12.5 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 EAQ85844.1 - 0.015 15.8 5.8 0.016 15.7 0.7 3.5 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 EAQ85844.1 - 0.026 14.4 2.4 0.75 9.8 0.5 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EAQ85844.1 - 0.026 14.7 2.3 0.52 10.6 1.5 3.0 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 EAQ85844.1 - 0.063 13.4 12.3 0.26 11.5 2.3 5.1 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.28 EAQ85844.1 - 0.13 12.1 2.0 0.78 9.7 1.8 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 EAQ85844.1 - 1.2 8.9 12.7 1.7 8.4 3.5 3.5 5 0 0 5 5 5 0 TPR repeat TPR_8 PF13181.6 EAQ85844.1 - 2.1 8.8 8.4 25 5.4 1.8 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat RabGAP-TBC PF00566.18 EAQ85845.1 - 1.9e-49 168.3 0.0 5.1e-49 166.8 0.0 1.7 1 1 0 1 1 1 1 Rab-GTPase-TBC domain RRM_1 PF00076.22 EAQ85846.1 - 1.7e-33 114.2 0.1 2.2e-15 56.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EAQ85846.1 - 3.8e-10 39.7 0.0 0.00041 20.4 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 EAQ85846.1 - 7.2e-05 22.7 0.0 0.065 13.2 0.0 2.5 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif TMEM239 PF15841.5 EAQ85846.1 - 0.022 14.6 0.6 0.044 13.7 0.6 1.4 1 0 0 1 1 1 0 Transmembrane protein 239 family DUF1631 PF07793.11 EAQ85846.1 - 3 6.2 9.4 7.3 4.9 9.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) PhyH PF05721.13 EAQ85847.1 - 4.6e-57 193.7 0.0 5.9e-57 193.3 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF3439 PF11921.8 EAQ85847.1 - 0.016 15.1 0.9 0.025 14.6 0.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) p450 PF00067.22 EAQ85848.1 - 1.8e-47 162.1 0.0 8.1e-47 160.0 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 Mpp10 PF04006.12 EAQ85848.1 - 0.00021 19.9 5.1 0.00029 19.4 5.1 1.1 1 0 0 1 1 1 1 Mpp10 protein BSP_II PF05432.11 EAQ85848.1 - 0.0072 16.1 11.7 0.012 15.3 11.7 1.3 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) SpoIIP PF07454.11 EAQ85848.1 - 0.014 14.9 2.0 7.7 5.9 4.0 2.2 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) CDC45 PF02724.14 EAQ85848.1 - 0.051 11.9 4.4 0.072 11.4 4.4 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4887 PF16228.5 EAQ85848.1 - 0.056 13.6 3.4 0.11 12.7 3.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4887) PAXIP1_C PF15364.6 EAQ85848.1 - 0.075 13.3 8.1 0.15 12.4 8.1 1.4 1 0 0 1 1 1 0 PAXIP1-associated-protein-1 C term PTIP binding protein Nop14 PF04147.12 EAQ85848.1 - 0.088 11.0 8.7 0.12 10.6 8.7 1.1 1 0 0 1 1 1 0 Nop14-like family Pox_Ag35 PF03286.14 EAQ85848.1 - 0.19 11.5 9.8 0.35 10.6 9.8 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein MPP6 PF10175.9 EAQ85848.1 - 0.34 11.4 6.4 0.69 10.4 6.4 1.4 1 0 0 1 1 1 0 M-phase phosphoprotein 6 Radial_spoke PF04712.12 EAQ85848.1 - 0.47 9.3 9.8 0.72 8.7 9.8 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein CENP-B_dimeris PF09026.10 EAQ85848.1 - 0.48 10.8 8.8 0.99 9.8 8.8 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DNA_pol_phi PF04931.13 EAQ85848.1 - 0.48 8.5 14.6 0.12 10.4 11.4 1.5 2 0 0 2 2 2 0 DNA polymerase phi TRAP_alpha PF03896.16 EAQ85848.1 - 0.5 9.5 8.3 0.94 8.6 8.3 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit NOA36 PF06524.12 EAQ85848.1 - 0.56 9.5 8.0 0.85 8.9 8.0 1.2 1 0 0 1 1 1 0 NOA36 protein DUF4637 PF15470.6 EAQ85848.1 - 0.9 9.2 13.2 1.7 8.4 13.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) GOLD_2 PF13897.6 EAQ85848.1 - 1 9.8 4.1 2.2 8.8 4.1 1.5 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking RPN2_C PF18004.1 EAQ85848.1 - 1.3 8.9 8.8 2.6 8.0 8.8 1.4 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain RXT2_N PF08595.11 EAQ85848.1 - 1.4 9.0 6.4 2.5 8.1 6.4 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal FAM176 PF14851.6 EAQ85848.1 - 1.6 8.4 9.7 3.1 7.4 9.7 1.5 1 0 0 1 1 1 0 FAM176 family RNA_pol_3_Rpc31 PF11705.8 EAQ85848.1 - 2.3 8.4 14.3 4.7 7.4 14.3 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Nucleo_P87 PF07267.11 EAQ85848.1 - 3 6.6 7.4 4.5 6.0 7.4 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Paf1 PF03985.13 EAQ85848.1 - 4.1 6.3 16.2 6 5.8 16.2 1.1 1 0 0 1 1 1 0 Paf1 Mis14 PF08641.12 EAQ85848.1 - 4.2 7.7 14.6 9.3 6.6 11.1 2.7 3 0 0 3 3 2 0 Kinetochore protein Mis14 like FYDLN_acid PF09538.10 EAQ85848.1 - 5.5 7.7 12.4 12 6.6 12.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) CPSF100_C PF13299.6 EAQ85848.1 - 8.6 6.5 7.4 17 5.6 7.4 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal ICL PF00463.21 EAQ85852.1 - 5.3e-299 992.1 0.8 6e-299 991.9 0.8 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 EAQ85852.1 - 3.2e-11 43.2 0.2 6.5e-11 42.1 0.0 1.6 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase SNF2_N PF00176.23 EAQ85853.1 - 1.8e-51 174.9 0.2 5.4e-51 173.4 0.2 1.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain VIGSSK PF14773.6 EAQ85853.1 - 1.9e-26 92.0 1.0 4.8e-26 90.6 1.0 1.8 1 0 0 1 1 1 1 Helicase-associated putative binding domain, C-terminal Helicase_C PF00271.31 EAQ85853.1 - 1.6e-20 73.5 0.0 6.1e-20 71.6 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EAQ85853.1 - 9.3e-08 32.3 0.0 3.2e-07 30.5 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EAQ85853.1 - 3.5e-07 29.7 0.0 6.8e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase DEAD PF00270.29 EAQ85853.1 - 0.00023 21.0 0.0 0.0012 18.7 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_34 PF13872.6 EAQ85853.1 - 0.059 12.3 1.9 1 8.2 0.1 2.6 3 0 0 3 3 3 0 P-loop containing NTP hydrolase pore-1 Ank_2 PF12796.7 EAQ85854.1 - 3.8e-26 91.5 23.2 2.7e-08 34.3 0.1 6.1 2 2 4 7 7 7 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAQ85854.1 - 8.1e-26 90.1 15.5 0.00018 22.0 0.0 8.7 6 1 2 8 8 8 7 Ankyrin repeats (many copies) Ank PF00023.30 EAQ85854.1 - 3.5e-24 84.1 17.2 0.0048 17.3 0.7 7.7 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 EAQ85854.1 - 4.5e-20 71.5 16.8 8e-06 26.0 0.2 6.4 4 1 1 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAQ85854.1 - 4.1e-13 48.2 17.2 0.04 14.5 0.2 10.2 10 0 0 10 10 10 3 Ankyrin repeat AAA_16 PF13191.6 EAQ85854.1 - 4.2e-08 33.8 0.0 2.8e-07 31.1 0.0 2.5 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 EAQ85854.1 - 6.8e-06 26.1 0.0 1.7e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 EAQ85854.1 - 0.00025 21.3 0.0 0.0012 19.2 0.0 2.1 1 1 1 2 2 2 1 AAA domain AAA PF00004.29 EAQ85854.1 - 0.00074 20.0 0.0 0.0034 17.8 0.0 2.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 EAQ85854.1 - 0.0054 16.9 0.0 3.3 7.9 0.0 2.9 2 0 0 2 2 2 1 AAA domain DUF676 PF05057.14 EAQ85854.1 - 0.0064 16.0 0.0 0.018 14.6 0.0 1.7 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_1 PF00561.20 EAQ85854.1 - 0.018 14.7 0.0 0.036 13.7 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold PGAP1 PF07819.13 EAQ85854.1 - 0.025 14.3 0.0 0.053 13.2 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein KAP_NTPase PF07693.14 EAQ85854.1 - 0.025 13.8 0.2 0.2 10.9 0.0 2.0 1 1 1 2 2 2 0 KAP family P-loop domain NB-ARC PF00931.22 EAQ85854.1 - 0.086 12.0 0.0 0.19 10.9 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_30 PF13604.6 EAQ85854.1 - 0.087 12.5 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Abhydrolase_6 PF12697.7 EAQ85854.1 - 0.13 12.8 0.0 0.13 12.8 0.0 5.2 4 2 0 4 4 2 0 Alpha/beta hydrolase family AidB_N PF18158.1 EAQ85855.1 - 9.7e-14 51.6 0.0 1.5e-13 51.0 0.0 1.2 1 0 0 1 1 1 1 Adaptive response protein AidB N-terminal domain Acyl-CoA_dh_M PF02770.19 EAQ85855.1 - 7.2e-09 35.7 0.0 1.9e-08 34.4 0.0 1.7 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Glyco_trans_2_3 PF13632.6 EAQ85856.1 - 7.3e-51 172.9 2.9 7.3e-51 172.9 2.9 2.8 2 1 0 3 3 3 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 EAQ85856.1 - 0.00017 21.4 0.0 0.00074 19.4 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 EAQ85856.1 - 0.026 14.0 0.0 0.055 12.9 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 21 TrbE PF11100.8 EAQ85856.1 - 0.31 11.3 5.2 0.23 11.7 2.4 2.3 2 0 0 2 2 2 0 Conjugal transfer protein TrbE MRP-L20 PF12824.7 EAQ85858.1 - 9.2e-58 195.0 3.5 1.3e-57 194.5 3.5 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Kelch_5 PF13854.6 EAQ85859.1 - 4.4e-07 29.7 0.2 3.7e-06 26.8 0.0 2.6 3 0 0 3 3 3 1 Kelch motif Kelch_6 PF13964.6 EAQ85859.1 - 0.0032 17.7 5.2 1.6 9.1 0.0 5.1 5 1 0 5 5 5 1 Kelch motif Kelch_4 PF13418.6 EAQ85859.1 - 0.041 13.9 6.3 5.6 7.1 0.0 5.1 5 0 0 5 5 5 0 Galactose oxidase, central domain Yip1 PF04893.17 EAQ85859.1 - 0.063 13.0 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Yip1 domain SfLAP PF11139.8 EAQ85859.1 - 0.12 11.8 0.3 15 4.9 0.1 2.3 2 0 0 2 2 2 0 Sap, sulfolipid-1-addressing protein Gram_pos_anchor PF00746.21 EAQ85859.1 - 0.28 11.2 2.6 1.9 8.5 2.6 2.4 1 1 0 1 1 1 0 LPXTG cell wall anchor motif Sororin PF09666.10 EAQ85860.1 - 0.009 16.2 1.2 0.015 15.5 0.2 1.9 2 0 0 2 2 2 1 Sororin protein PTR2 PF00854.21 EAQ85861.1 - 9.8e-64 215.6 0.4 2.3e-63 214.4 0.4 1.5 2 0 0 2 2 2 1 POT family MFS_1 PF07690.16 EAQ85861.1 - 4.4e-06 25.9 4.6 4.4e-06 25.9 4.6 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily CDC24_OB1 PF17246.2 EAQ85861.1 - 0.039 14.1 0.0 0.061 13.4 0.0 1.3 1 0 0 1 1 1 0 Cell division control protein 24, OB domain 1 GATase_6 PF13522.6 EAQ85864.1 - 1.5e-16 60.8 0.0 2.8e-16 60.0 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 EAQ85864.1 - 5.3e-14 52.2 0.0 1.1e-13 51.2 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 EAQ85864.1 - 5.1e-06 25.6 0.0 8.1e-06 24.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Pribosyltran PF00156.27 EAQ85864.1 - 0.056 13.0 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Phosphoribosyl transferase domain Trehalase PF01204.18 EAQ85865.1 - 2.7e-196 653.4 0.0 3.2e-196 653.1 0.0 1.1 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.11 EAQ85865.1 - 2.4e-17 62.3 0.6 4.2e-17 61.6 0.6 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain Rubis-subs-bind PF09273.11 EAQ85866.1 - 4.4e-23 82.4 0.0 7.5e-23 81.6 0.0 1.4 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.28 EAQ85866.1 - 2.3e-11 44.4 0.0 3.8e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 SET domain DUF1601 PF07671.11 EAQ85866.1 - 0.057 13.3 0.2 0.11 12.3 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1601) DUF3405 PF11885.8 EAQ85867.1 - 3.4e-207 689.1 0.7 4.1e-207 688.9 0.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) Glyco_hydro_10 PF00331.20 EAQ85870.1 - 1.1e-26 93.8 0.0 1.2e-26 93.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Glyco_hydro_3_C PF01915.22 EAQ85871.1 - 1.6e-38 132.8 0.0 3.1e-38 131.8 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 EAQ85871.1 - 9.3e-23 80.1 0.6 1.7e-22 79.3 0.2 1.7 2 0 0 2 2 2 1 Fibronectin type III-like domain Glyco_hydro_3 PF00933.21 EAQ85871.1 - 7.4e-21 74.8 0.1 1.1e-16 61.2 0.0 2.2 1 1 1 2 2 2 2 Glycosyl hydrolase family 3 N terminal domain G-alpha PF00503.20 EAQ85872.1 - 1.2e-111 373.3 0.4 1.4e-111 373.1 0.4 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EAQ85872.1 - 5e-14 52.1 1.0 1.8e-08 34.0 0.1 2.5 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EAQ85872.1 - 0.00019 20.8 1.8 0.0097 15.3 0.1 2.4 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 EAQ85872.1 - 0.016 15.4 0.7 6 7.1 0.1 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_18 PF13238.6 EAQ85872.1 - 0.022 15.3 0.0 0.073 13.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain Spore_YpjB PF09577.10 EAQ85872.1 - 0.034 14.0 0.3 0.42 10.4 0.1 2.2 2 0 0 2 2 2 0 Sporulation protein YpjB (SpoYpjB) FtsK_SpoIIIE PF01580.18 EAQ85872.1 - 0.045 13.1 0.0 0.077 12.3 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_25 PF13481.6 EAQ85872.1 - 0.079 12.5 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EAQ85872.1 - 0.13 12.0 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Spermine_synth PF01564.17 EAQ85874.1 - 6.3e-75 250.7 0.0 1e-74 250.0 0.0 1.3 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 EAQ85874.1 - 1.7e-24 85.5 0.1 2.8e-24 84.8 0.1 1.4 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 EAQ85874.1 - 4.5e-05 24.1 0.0 0.00012 22.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EAQ85874.1 - 0.00067 20.4 0.3 0.0024 18.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain DUF43 PF01861.16 EAQ85874.1 - 0.0038 16.5 0.0 0.0059 15.9 0.0 1.2 1 0 0 1 1 1 1 Branched-chain polyamine synthase A C-terminal domain Methyltransf_18 PF12847.7 EAQ85874.1 - 0.046 13.6 0.0 0.088 12.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 EAQ85874.1 - 0.063 12.8 0.0 0.088 12.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_2 PF00891.18 EAQ85874.1 - 0.11 11.8 0.2 0.46 9.8 0.1 1.9 1 1 1 2 2 2 0 O-methyltransferase domain Methyltransf_30 PF05430.11 EAQ85874.1 - 0.15 11.9 0.0 0.33 10.8 0.0 1.6 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase CN_hydrolase PF00795.22 EAQ85875.1 - 4.5e-30 104.9 0.1 3.3e-23 82.3 0.0 3.0 2 1 1 3 3 3 3 Carbon-nitrogen hydrolase AT_hook PF02178.19 EAQ85876.1 - 1 9.4 7.4 2.4 8.3 7.4 1.7 1 0 0 1 1 1 0 AT hook motif Uds1 PF15456.6 EAQ85877.1 - 9.7e-32 109.9 9.7 9.7e-32 109.9 9.7 2.1 2 0 0 2 2 2 1 Up-regulated During Septation FTA4 PF13093.6 EAQ85877.1 - 0.015 15.2 1.4 0.035 14.0 1.4 1.6 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Wbp11 PF09429.10 EAQ85877.1 - 0.9 10.0 5.6 0.23 11.9 0.6 2.4 2 0 0 2 2 2 0 WW domain binding protein 11 Peptidase_M1 PF01433.20 EAQ85880.1 - 6.9e-45 153.3 0.4 1e-44 152.7 0.4 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 EAQ85880.1 - 1.8e-39 134.3 0.1 3.4e-39 133.4 0.1 1.5 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 EAQ85880.1 - 5.3e-28 98.5 0.0 8.8e-28 97.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_M61 PF05299.12 EAQ85880.1 - 0.076 13.4 1.3 2.4 8.6 1.3 2.7 1 1 0 1 1 1 0 M61 glycyl aminopeptidase Kinesin PF00225.23 EAQ85881.1 - 1.9e-111 372.2 2.1 2.2e-111 372.0 0.0 2.0 2 0 0 2 2 2 1 Kinesin motor domain Kinesin_assoc PF16183.5 EAQ85881.1 - 6.3e-36 124.2 13.2 1.9e-30 106.3 0.3 3.9 2 1 1 3 3 3 2 Kinesin-associated DUF3694 PF12473.8 EAQ85881.1 - 1.6e-31 110.0 0.1 5.5e-31 108.3 0.1 1.9 1 0 0 1 1 1 1 Kinesin protein Microtub_bd PF16796.5 EAQ85881.1 - 3.9e-25 88.5 0.4 9.5e-25 87.3 0.0 1.9 2 0 0 2 2 2 1 Microtubule binding FHA PF00498.26 EAQ85881.1 - 8.5e-06 26.0 0.0 5.7e-05 23.4 0.1 2.4 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 EAQ85881.1 - 0.039 14.3 0.0 0.12 12.7 0.0 1.9 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain KIF1B PF12423.8 EAQ85881.1 - 0.096 13.1 6.9 0.23 11.9 0.2 2.9 2 0 0 2 2 2 0 Kinesin protein 1B E2F_CC-MB PF16421.5 EAQ85881.1 - 0.54 10.7 11.8 0.093 13.1 3.7 3.0 3 0 0 3 3 3 0 E2F transcription factor CC-MB domain UPF0242 PF06785.11 EAQ85881.1 - 1.3 9.1 17.1 2.6 8.1 0.8 2.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Golgin_A5 PF09787.9 EAQ85881.1 - 3.4 7.0 19.1 1.9 7.9 13.0 2.4 2 0 0 2 2 2 0 Golgin subfamily A member 5 Methyltransf_11 PF08241.12 EAQ85883.1 - 2.3e-13 50.6 0.0 5.6e-13 49.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EAQ85883.1 - 1.4e-12 47.8 0.0 2.2e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAQ85883.1 - 5e-11 43.2 0.1 6.3e-10 39.6 0.1 2.4 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EAQ85883.1 - 6.7e-10 38.7 0.3 3.6e-07 29.8 0.2 2.8 2 1 0 2 2 2 2 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 EAQ85883.1 - 1.4e-09 38.5 0.0 1e-08 35.8 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAQ85883.1 - 1.9e-08 34.3 0.0 8.2e-07 28.9 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EAQ85883.1 - 0.097 12.2 0.9 0.5 9.9 0.1 2.3 2 1 0 3 3 3 0 Methyltransferase small domain Methyltransf_PK PF05891.12 EAQ85883.1 - 0.1 12.1 0.1 0.62 9.5 0.1 2.0 1 1 0 1 1 1 0 AdoMet dependent proline di-methyltransferase MetW PF07021.12 EAQ85883.1 - 0.24 11.0 0.1 0.54 9.8 0.1 1.6 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW DUF5598 PF18127.1 EAQ85884.1 - 0.13 12.7 0.0 0.3 11.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5598) DNMT1-RFD PF12047.8 EAQ85884.1 - 0.17 11.9 0.0 0.36 10.9 0.0 1.5 1 0 0 1 1 1 0 Cytosine specific DNA methyltransferase replication foci domain TruB_N PF01509.18 EAQ85885.1 - 1e-08 35.6 0.6 1.9e-08 34.8 0.6 1.4 1 0 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 EAQ85885.1 - 7.8e-06 25.9 0.0 1.5e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain Sec2p PF06428.11 EAQ85886.1 - 6.1e-13 48.6 7.6 3.1e-12 46.3 3.9 2.3 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p Exonuc_VII_L PF02601.15 EAQ85886.1 - 0.0056 16.3 2.3 0.012 15.2 0.1 1.9 1 1 1 2 2 2 1 Exonuclease VII, large subunit DASH_Spc19 PF08287.11 EAQ85886.1 - 0.024 14.5 1.5 0.024 14.5 1.5 2.2 2 0 0 2 2 2 0 Spc19 DUF4407 PF14362.6 EAQ85886.1 - 0.076 12.4 5.7 0.44 9.9 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF4795 PF16043.5 EAQ85886.1 - 0.13 11.8 1.9 1.4 8.5 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) Laminin_II PF06009.12 EAQ85886.1 - 0.16 12.0 2.1 10 6.1 0.1 2.2 2 0 0 2 2 2 0 Laminin Domain II DUF4763 PF15960.5 EAQ85886.1 - 0.21 10.9 4.1 3.5 6.9 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4763) HrpB7 PF09486.10 EAQ85886.1 - 0.26 11.6 21.7 0.3 11.5 7.4 2.4 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) MscS_porin PF12795.7 EAQ85886.1 - 0.36 10.3 23.2 0.73 9.3 2.5 2.2 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain Atg14 PF10186.9 EAQ85886.1 - 0.4 9.7 10.6 0.56 9.2 0.1 2.3 2 1 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Fez1 PF06818.15 EAQ85886.1 - 0.4 11.1 6.1 1.9 8.9 0.1 2.2 2 0 0 2 2 2 0 Fez1 Jnk-SapK_ap_N PF09744.9 EAQ85886.1 - 0.54 10.5 13.2 0.59 10.4 4.0 2.2 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 RmuC PF02646.16 EAQ85886.1 - 0.78 8.8 6.6 0.35 10.0 1.3 2.2 2 0 0 2 2 2 0 RmuC family HOOK PF05622.12 EAQ85886.1 - 1 7.4 6.4 2.9 6.0 0.7 2.1 2 0 0 2 2 2 0 HOOK protein HAUS-augmin3 PF14932.6 EAQ85886.1 - 1.8 8.1 9.9 2.5 7.6 0.8 2.2 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 SPX PF03105.19 EAQ85886.1 - 3.9 7.3 11.8 5.6 6.8 11.8 1.2 1 0 0 1 1 1 0 SPX domain APG6_N PF17675.1 EAQ85886.1 - 4.2 7.9 13.7 7.5 7.1 3.7 2.3 2 0 0 2 2 2 0 Apg6 coiled-coil region GCN5L1 PF06320.13 EAQ85886.1 - 6.1 7.0 6.3 0.47 10.6 0.5 1.9 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) Spc7 PF08317.11 EAQ85886.1 - 9.6 5.0 10.1 5.5 5.8 1.1 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein EXOSC1 PF10447.9 EAQ85887.1 - 8.9e-14 52.0 0.1 1.3e-13 51.4 0.1 1.3 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 ECR1_N PF14382.6 EAQ85887.1 - 2.9e-11 43.0 0.1 7.1e-11 41.7 0.0 1.7 2 0 0 2 2 2 1 Exosome complex exonuclease RRP4 N-terminal region S-l_SbsC_C PF18316.1 EAQ85887.1 - 0.018 15.5 0.0 0.03 14.8 0.0 1.4 1 0 0 1 1 1 0 S-layer protein SbsC C-terminal domain ERG2_Sigma1R PF04622.12 EAQ85888.1 - 3.2e-95 317.4 0.1 3.7e-95 317.2 0.1 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein NmrA PF05368.13 EAQ85889.1 - 1.2e-83 280.2 0.0 1.5e-83 280.0 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EAQ85889.1 - 2.5e-08 34.0 0.0 9e-08 32.2 0.0 1.7 1 1 0 1 1 1 1 NAD(P)H-binding DUF3798 PF12683.7 EAQ85889.1 - 0.036 13.5 0.0 0.055 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3798) DUF2498 PF10692.9 EAQ85889.1 - 0.11 12.4 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2498) Fcf1 PF04900.12 EAQ85890.1 - 9.2e-14 51.6 0.3 3.6e-13 49.8 0.1 1.8 2 0 0 2 2 2 1 Fcf1 PIN_9 PF18477.1 EAQ85890.1 - 0.00017 21.9 0.0 0.0003 21.1 0.0 1.4 1 0 0 1 1 1 1 PIN like domain Jag_N PF14804.6 EAQ85890.1 - 0.025 14.9 0.1 0.046 14.1 0.1 1.3 1 0 0 1 1 1 0 Jag N-terminus RRM_1 PF00076.22 EAQ85893.1 - 2e-18 66.0 0.0 2.9e-18 65.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EAQ85893.1 - 0.00033 20.3 0.0 0.00049 19.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1793 PF08760.11 EAQ85894.1 - 1.2e-73 247.0 0.1 4.6e-73 245.1 0.0 2.0 3 0 0 3 3 3 1 Domain of unknown function (DUF1793) DUF4965 PF16335.5 EAQ85894.1 - 4.6e-67 225.0 0.8 2.8e-52 176.9 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4965) DUF5127 PF17168.4 EAQ85894.1 - 9.8e-40 136.7 0.2 1.6e-39 136.1 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) Bac_rhamnosid6H PF17389.2 EAQ85894.1 - 0.0026 17.1 0.3 0.45 9.7 0.1 2.5 2 0 0 2 2 2 2 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain SNF2_N PF00176.23 EAQ85895.1 - 2e-48 164.9 0.1 6.9e-44 150.0 0.0 2.6 3 0 0 3 3 3 2 SNF2 family N-terminal domain Helicase_C PF00271.31 EAQ85895.1 - 4.5e-16 59.2 0.0 3e-15 56.5 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.25 EAQ85895.1 - 3.4e-08 33.2 11.2 3.4e-08 33.2 11.2 2.3 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.15 EAQ85895.1 - 2.6e-07 30.8 0.5 8.3e-07 29.2 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAQ85895.1 - 9.7e-05 22.2 0.0 0.00022 21.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-C3HC4_3 PF13920.6 EAQ85895.1 - 0.00011 22.0 8.5 0.00011 22.0 8.5 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EAQ85895.1 - 0.00019 21.2 9.2 0.00019 21.2 9.2 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EAQ85895.1 - 0.00037 20.8 10.2 0.00037 20.8 10.2 2.6 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 EAQ85895.1 - 0.0078 16.1 10.2 0.0078 16.1 10.2 2.4 2 0 0 2 2 1 1 zinc-RING finger domain AAA_34 PF13872.6 EAQ85895.1 - 0.014 14.3 0.0 0.042 12.7 0.0 1.7 2 0 0 2 2 2 0 P-loop containing NTP hydrolase pore-1 ERCC3_RAD25_C PF16203.5 EAQ85895.1 - 0.042 13.1 0.0 0.069 12.3 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase DUF2603 PF10788.9 EAQ85895.1 - 0.057 13.5 0.3 3.5 7.7 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2603) zf-Nse PF11789.8 EAQ85895.1 - 0.26 11.1 4.7 0.74 9.7 4.7 1.8 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 EAQ85895.1 - 0.32 11.1 10.1 1.1 9.3 10.1 2.0 1 0 0 1 1 1 0 RING-type zinc-finger zf-UDP PF14569.6 EAQ85895.1 - 1.1 9.5 5.1 4.8 7.4 5.1 2.1 1 1 0 1 1 1 0 Zinc-binding RING-finger Zn_Tnp_IS91 PF14319.6 EAQ85895.1 - 5.5 7.1 16.3 0.55 10.3 4.1 2.8 2 1 0 2 2 2 0 Transposase zinc-binding domain LRR_6 PF13516.6 EAQ85896.1 - 3.1e-07 29.9 0.2 0.02 14.9 0.0 5.9 7 0 0 7 7 7 1 Leucine Rich repeat LRR_4 PF12799.7 EAQ85896.1 - 0.002 18.5 0.4 44 4.7 0.0 5.1 6 2 2 8 8 8 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EAQ85896.1 - 0.033 13.9 0.0 4.9 7.0 0.0 3.3 3 0 0 3 3 3 0 Leucine rich repeat FYVE_2 PF02318.16 EAQ85896.1 - 0.039 14.2 0.4 0.098 12.9 0.4 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger GATA PF00320.27 EAQ85896.1 - 0.09 12.4 5.4 0.092 12.4 1.8 2.4 2 0 0 2 2 2 0 GATA zinc finger NinF PF05810.12 EAQ85896.1 - 0.17 11.8 0.5 11 6.0 0.0 2.9 2 1 0 2 2 2 0 NinF protein Malic_M PF03949.15 EAQ85897.1 - 4.1e-93 311.4 0.0 6e-93 310.8 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 EAQ85897.1 - 2.5e-69 232.7 0.0 4e-69 232.0 0.0 1.4 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain PadR PF03551.14 EAQ85897.1 - 0.12 12.3 0.1 1.5 8.9 0.0 2.3 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family POT1 PF02765.17 EAQ85898.1 - 3.3e-08 33.5 0.0 7.9e-08 32.2 0.0 1.6 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 FMO-like PF00743.19 EAQ85899.1 - 7.8e-44 150.0 0.0 2.2e-27 95.7 0.1 3.0 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like NAD_binding_9 PF13454.6 EAQ85899.1 - 2.4e-13 50.4 0.0 1.3e-12 48.0 0.0 2.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 EAQ85899.1 - 3.5e-13 49.5 3.4 3.4e-07 29.8 1.2 3.1 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EAQ85899.1 - 8.9e-13 48.1 0.0 1.4e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EAQ85899.1 - 2.3e-10 40.1 0.7 5.1e-08 32.4 0.1 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 EAQ85899.1 - 2.6e-07 30.1 0.0 2.5e-05 23.6 0.0 2.5 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 EAQ85899.1 - 1.4e-06 28.4 0.0 3.9e-06 27.0 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EAQ85899.1 - 2.7e-05 23.9 0.1 0.0087 15.7 0.0 3.0 2 1 0 3 3 3 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EAQ85899.1 - 0.0077 15.0 0.2 0.051 12.3 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 EAQ85899.1 - 0.023 15.2 0.1 2.9 8.5 0.0 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EAQ85899.1 - 0.025 13.8 0.0 0.051 12.8 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Shikimate_DH PF01488.20 EAQ85899.1 - 0.029 14.4 0.0 0.2 11.7 0.0 2.1 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase MCRA PF06100.11 EAQ85899.1 - 0.039 12.8 0.0 0.069 11.9 0.0 1.3 1 0 0 1 1 1 0 MCRA family Glu_dehyd_C PF16912.5 EAQ85899.1 - 0.16 11.5 0.0 0.99 8.8 0.0 2.1 3 0 0 3 3 3 0 Glucose dehydrogenase C-terminus Aminotran_1_2 PF00155.21 EAQ85900.1 - 3.8e-10 39.5 0.0 1.6e-08 34.1 0.0 2.3 2 0 0 2 2 2 2 Aminotransferase class I and II LTV PF04180.14 EAQ85901.1 - 2.1e-110 370.0 11.5 2.5e-110 369.8 11.5 1.0 1 0 0 1 1 1 1 Low temperature viability protein Cdh1_DBD_1 PF18196.1 EAQ85901.1 - 0.23 11.8 1.9 0.34 11.2 0.3 2.1 1 1 0 1 1 1 0 Chromodomain helicase DNA-binding domain 1 MMR_HSR1 PF01926.23 EAQ85902.1 - 3e-17 62.7 0.1 3e-15 56.3 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EAQ85902.1 - 1.6e-07 31.0 0.2 7e-06 25.7 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EAQ85902.1 - 2.8e-06 27.3 0.0 0.017 15.1 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 EAQ85902.1 - 0.00067 19.7 0.0 0.073 13.1 0.0 2.4 2 0 0 2 2 2 1 Dynamin family AIG1 PF04548.16 EAQ85902.1 - 0.011 15.1 0.0 0.02 14.2 0.0 1.4 1 0 0 1 1 1 0 AIG1 family cobW PF02492.19 EAQ85902.1 - 0.17 11.4 0.2 0.66 9.5 0.0 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 EAQ85902.1 - 1.6 9.1 3.6 3 8.2 0.0 2.8 1 1 2 3 3 3 0 AAA ATPase domain Ribosomal_L5_C PF00673.21 EAQ85903.1 - 1.2e-26 92.7 0.0 2.1e-26 91.9 0.0 1.4 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 EAQ85903.1 - 1.3e-08 35.0 0.0 2.1e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L5 Fes1 PF08609.10 EAQ85904.1 - 3.1e-32 111.3 7.4 1.9e-31 108.8 7.4 2.2 1 1 0 1 1 1 1 Nucleotide exchange factor Fes1 Arm PF00514.23 EAQ85904.1 - 2.5e-05 24.2 0.2 0.1 12.7 0.1 2.5 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 EAQ85904.1 - 0.00091 19.7 0.5 0.0027 18.2 0.3 2.0 1 1 0 1 1 1 1 HEAT-like repeat HEAT_2 PF13646.6 EAQ85904.1 - 0.0012 19.1 3.3 0.0016 18.8 1.7 2.0 2 1 0 2 2 2 1 HEAT repeats HEAT PF02985.22 EAQ85904.1 - 0.003 17.7 0.5 0.47 10.9 0.1 2.8 2 0 0 2 2 2 1 HEAT repeat Actin PF00022.19 EAQ85905.1 - 1e-141 472.3 0.0 6.9e-140 466.3 0.0 2.7 1 1 0 1 1 1 1 Actin RF-1 PF00472.20 EAQ85906.1 - 0.00089 19.2 4.4 0.0029 17.5 0.1 2.3 1 1 1 2 2 2 2 RF-1 domain TT_ORF2 PF02957.15 EAQ85906.1 - 0.41 11.6 6.0 0.34 11.9 4.2 1.7 1 1 0 1 1 1 0 TT viral ORF2 WD40 PF00400.32 EAQ85907.1 - 1.4e-30 104.9 17.4 0.0037 18.1 0.0 11.7 12 0 0 12 12 12 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAQ85907.1 - 6.7e-07 29.5 0.4 3.5 8.0 0.0 6.5 6 2 0 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Mak_N_cap PF18085.1 EAQ85907.1 - 0.99 10.5 4.6 1.8e+02 3.2 0.2 4.6 4 1 0 4 4 4 0 Maltokinase N-terminal cap domain zf-C2H2 PF00096.26 EAQ85908.1 - 0.13 12.8 0.2 0.13 12.8 0.2 2.0 2 0 0 2 2 2 0 Zinc finger, C2H2 type RRM_1 PF00076.22 EAQ85911.1 - 2.1e-33 113.9 0.0 2.4e-15 56.1 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.11 EAQ85911.1 - 0.0045 16.7 0.1 3.2 7.5 0.0 2.4 2 0 0 2 2 2 2 Ribonuclease B OB domain RRM_5 PF13893.6 EAQ85911.1 - 0.014 15.0 0.0 0.2 11.3 0.0 2.1 1 1 1 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 EAQ85911.1 - 0.11 12.8 0.0 1.5 9.0 0.0 2.2 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter Limkain-b1 PF11608.8 EAQ85911.1 - 0.13 12.4 0.0 3.9 7.6 0.0 2.2 2 0 0 2 2 2 0 Limkain b1 RRM_7 PF16367.5 EAQ85911.1 - 0.15 12.2 0.0 2.1 8.5 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif MIF4G_like PF09088.11 EAQ85912.1 - 2.4e-95 317.7 0.2 3.9e-95 317.1 0.2 1.3 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.11 EAQ85912.1 - 8.9e-69 231.9 0.3 3e-68 230.2 0.2 1.8 2 0 0 2 2 2 1 MIF4G like MscS_TM PF12794.7 EAQ85912.1 - 0.56 9.0 5.9 0.97 8.2 5.9 1.4 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Pkinase PF00069.25 EAQ85913.1 - 2.2e-65 220.7 0.0 2.5e-65 220.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ85913.1 - 1e-25 90.6 0.0 1.3e-25 90.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAQ85913.1 - 1.3e-06 28.0 0.0 6.1e-06 25.7 0.0 1.8 1 1 1 2 2 2 1 Kinase-like APH PF01636.23 EAQ85913.1 - 0.0009 19.2 0.3 0.0051 16.8 0.0 2.0 2 1 1 3 3 3 1 Phosphotransferase enzyme family DUF1229 PF06797.11 EAQ85913.1 - 0.019 15.2 0.1 0.031 14.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1229) Kdo PF06293.14 EAQ85913.1 - 0.066 12.6 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EAQ85913.1 - 0.075 12.6 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Choline_kinase PF01633.20 EAQ85913.1 - 0.083 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Presenilin PF01080.17 EAQ85914.1 - 1.8 7.2 2.8 2.1 7.1 2.8 1.0 1 0 0 1 1 1 0 Presenilin NPR3 PF03666.13 EAQ85914.1 - 5.1 5.8 5.4 5.6 5.6 5.4 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 UPF0220 PF05255.11 EAQ85915.1 - 8.3e-66 220.6 4.0 9.3e-66 220.5 4.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) DUF5337 PF17272.2 EAQ85915.1 - 0.87 9.5 4.0 0.3 10.9 0.4 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5337) SMI1_KNR4 PF09346.10 EAQ85916.1 - 2.9e-33 115.1 0.0 7.1e-33 113.8 0.0 1.7 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) SUKH_5 PF14567.6 EAQ85916.1 - 0.12 12.2 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 SMI1-KNR4 cell-wall Sec8_exocyst PF04048.14 EAQ85917.1 - 7.1e-14 51.9 0.1 8.6e-07 28.9 0.0 2.6 1 1 1 2 2 2 2 Sec8 exocyst complex component specific domain DUF4327 PF14217.6 EAQ85917.1 - 0.047 13.8 0.8 0.16 12.1 0.0 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4327) IZUMO PF15005.6 EAQ85917.1 - 0.16 12.4 2.6 0.2 12.1 0.2 2.3 3 0 0 3 3 3 0 Izumo sperm-egg fusion, Ig domain-associated RAI1 PF08652.11 EAQ85918.1 - 6.8e-26 90.2 0.1 1.6e-25 89.1 0.0 1.7 2 0 0 2 2 2 1 RAI1 like PD-(D/E)XK nuclease Pkinase PF00069.25 EAQ85919.1 - 8.6e-56 189.2 0.0 1.2e-55 188.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ85919.1 - 7e-40 136.9 0.0 1e-39 136.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EAQ85919.1 - 9.1e-06 24.7 0.0 2e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EAQ85919.1 - 0.0012 18.3 0.0 0.0023 17.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like DUF3915 PF13054.6 EAQ85919.1 - 0.021 14.8 8.0 0.037 14.0 8.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Transglut_core PF01841.19 EAQ85920.1 - 1.7e-11 44.5 0.2 8.1e-11 42.4 0.1 2.2 2 0 0 2 2 2 1 Transglutaminase-like superfamily SH3_2 PF07653.17 EAQ85920.1 - 2.5e-08 33.5 0.2 5.3e-08 32.4 0.2 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EAQ85920.1 - 6.1e-05 22.5 2.3 9.7e-05 21.9 0.1 2.3 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 EAQ85920.1 - 0.027 14.3 0.1 0.062 13.2 0.1 1.7 1 0 0 1 1 1 0 Variant SH3 domain ABC_tran PF00005.27 EAQ85921.1 - 1.3e-13 51.6 0.1 1.1e-12 48.7 0.1 2.1 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EAQ85921.1 - 2.2e-11 44.1 0.3 0.00017 21.5 0.1 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system DUF3584 PF12128.8 EAQ85921.1 - 0.0017 16.0 0.3 0.0022 15.6 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) AAA_29 PF13555.6 EAQ85921.1 - 0.002 17.8 0.3 0.0038 16.9 0.3 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_28 PF13521.6 EAQ85921.1 - 0.0023 18.2 0.7 0.03 14.6 0.2 2.1 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 EAQ85921.1 - 0.0041 17.6 0.1 0.0058 17.2 0.1 1.2 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 EAQ85921.1 - 0.0045 16.5 0.0 2 7.8 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EAQ85921.1 - 0.0084 16.4 0.1 0.018 15.3 0.1 1.7 1 1 0 1 1 1 1 AAA domain Arf PF00025.21 EAQ85921.1 - 0.0092 15.4 0.0 0.018 14.5 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family PduV-EutP PF10662.9 EAQ85921.1 - 0.016 14.9 0.0 0.024 14.4 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 EAQ85921.1 - 0.017 15.0 0.0 0.026 14.4 0.0 1.2 1 0 0 1 1 1 0 RsgA GTPase AAA_15 PF13175.6 EAQ85921.1 - 0.02 14.6 0.0 0.028 14.1 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain AAA_16 PF13191.6 EAQ85921.1 - 0.028 14.8 1.7 0.089 13.2 1.7 1.9 1 1 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 EAQ85921.1 - 0.052 14.0 0.1 0.22 11.9 0.1 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EAQ85921.1 - 0.056 13.0 0.5 0.1 12.2 0.5 1.6 1 1 0 1 1 1 0 AAA domain Roc PF08477.13 EAQ85921.1 - 0.11 12.7 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_33 PF13671.6 EAQ85921.1 - 0.12 12.6 0.1 0.25 11.5 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_13 PF13166.6 EAQ85921.1 - 0.13 10.9 0.1 0.18 10.4 0.1 1.1 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 EAQ85921.1 - 0.16 11.6 0.1 0.22 11.1 0.1 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Nsp2a_N PF17896.1 EAQ85921.1 - 0.24 10.6 0.0 0.33 10.1 0.0 1.2 1 0 0 1 1 1 0 Replicase polyprotein 1a N-terminal domain CENP-I PF07778.11 EAQ85922.1 - 4.3e-22 78.5 0.4 5.7e-17 61.6 0.0 2.3 2 1 0 2 2 2 2 Mis6 Acetyltransf_1 PF00583.25 EAQ85923.1 - 0.00011 22.4 0.0 0.00028 21.1 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EAQ85923.1 - 0.0008 19.4 0.0 0.0014 18.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EAQ85923.1 - 0.00094 19.6 0.0 0.0019 18.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3384 PF11864.8 EAQ85924.1 - 1.3e-139 466.2 1.5 6.8e-139 463.9 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3384) Rap_GAP PF02145.15 EAQ85924.1 - 3.3e-41 140.9 0.1 2e-33 115.5 0.1 2.8 1 1 1 2 2 2 2 Rap/ran-GAP Tuberin PF03542.16 EAQ85924.1 - 4.4e-34 118.1 8.4 2.8e-30 105.6 0.4 3.8 3 1 1 4 4 4 3 Tuberin DUF3361 PF11841.8 EAQ85924.1 - 0.075 13.0 0.0 0.5 10.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3361) CAS_CSE1 PF03378.15 EAQ85925.1 - 1.1e-188 627.3 0.0 2.5e-188 626.1 0.0 1.6 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus Cse1 PF08506.10 EAQ85925.1 - 4.3e-149 496.4 0.8 7.1e-149 495.6 0.8 1.4 1 0 0 1 1 1 1 Cse1 IBN_N PF03810.19 EAQ85925.1 - 3.4e-14 52.5 0.1 1.1e-13 50.9 0.1 2.0 1 0 0 1 1 1 1 Importin-beta N-terminal domain Xpo1 PF08389.12 EAQ85925.1 - 0.048 13.7 0.8 4 7.5 0.0 3.8 3 2 0 3 3 3 0 Exportin 1-like protein RRN3 PF05327.11 EAQ85926.1 - 0.36 9.3 2.5 0.53 8.8 2.5 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Cwf_Cwc_15 PF04889.12 EAQ85926.1 - 0.57 9.9 11.4 1.3 8.8 11.4 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 EAQ85926.1 - 1.5 8.0 8.7 2.4 7.4 8.7 1.2 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.10 EAQ85926.1 - 5.6 7.4 11.3 12 6.3 11.3 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Pkinase PF00069.25 EAQ85927.1 - 1.3e-46 159.1 0.0 3.3e-46 157.8 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ85927.1 - 4.7e-23 81.8 0.0 5.6e-20 71.7 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 EAQ85927.1 - 8.2e-05 21.7 0.0 0.00011 21.3 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EAQ85927.1 - 0.00061 19.8 0.5 0.0072 16.3 0.5 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EAQ85927.1 - 0.00062 19.2 0.1 0.018 14.3 0.1 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 EAQ85927.1 - 0.00077 18.9 0.0 0.0012 18.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EAQ85927.1 - 0.0085 14.9 0.0 0.013 14.3 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 EAQ85927.1 - 0.081 12.0 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 WD40 PF00400.32 EAQ85928.1 - 3.1e-21 75.3 16.0 8.7e-06 26.4 0.2 7.4 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAQ85928.1 - 2.1e-13 50.4 3.3 0.011 16.1 0.0 4.7 2 2 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EAQ85928.1 - 1.3e-06 28.4 0.0 2.9e-05 24.0 0.0 2.2 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 EAQ85928.1 - 0.096 12.7 0.1 33 4.6 0.0 3.0 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Nbas_N PF15492.6 EAQ85928.1 - 0.12 11.7 0.0 0.26 10.6 0.0 1.6 1 0 0 1 1 1 0 Neuroblastoma-amplified sequence, N terminal Dynamin_M PF01031.20 EAQ85929.1 - 1.8e-102 342.4 0.0 3.2e-102 341.6 0.0 1.4 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 EAQ85929.1 - 2e-57 193.9 0.0 3.7e-57 193.0 0.0 1.5 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 EAQ85929.1 - 1.1e-29 102.5 4.3 1.1e-29 102.5 4.3 2.4 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 EAQ85929.1 - 1.1e-05 25.5 0.3 0.00014 21.9 0.3 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_15 PF13175.6 EAQ85929.1 - 0.0082 15.9 0.5 2.1 7.9 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain CoA_transf_3 PF02515.17 EAQ85930.1 - 3.6e-20 72.4 0.0 4.7e-20 72.0 0.0 1.2 1 0 0 1 1 1 1 CoA-transferase family III Glutaredoxin PF00462.24 EAQ85931.1 - 0.0011 19.1 0.0 0.0022 18.2 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin adh_short PF00106.25 EAQ85932.1 - 3.1e-11 43.1 0.0 2.9e-10 39.9 0.1 2.1 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 EAQ85932.1 - 1.7e-08 34.6 0.1 2.6e-08 34.0 0.1 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 EAQ85932.1 - 0.00011 21.8 0.1 0.00023 20.8 0.1 1.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 EAQ85932.1 - 0.13 11.7 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family G_glu_transpept PF01019.21 EAQ85933.1 - 1.8e-117 393.3 0.0 4.5e-117 391.9 0.0 1.6 1 1 0 1 1 1 1 Gamma-glutamyltranspeptidase GST_N_3 PF13417.6 EAQ85934.1 - 2.5e-07 31.0 0.0 4.1e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EAQ85934.1 - 5.3e-05 23.4 0.5 0.00011 22.4 0.5 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain PPTA PF01239.22 EAQ85934.1 - 0.091 12.5 0.8 0.24 11.2 0.9 1.6 2 0 0 2 2 2 0 Protein prenyltransferase alpha subunit repeat tRNA-synt_1b PF00579.25 EAQ85935.1 - 1.9e-17 63.5 0.3 7.4e-10 38.6 0.0 2.7 3 0 0 3 3 3 2 tRNA synthetases class I (W and Y) DUF1682 PF07946.14 EAQ85935.1 - 0.057 12.6 3.1 0.084 12.1 3.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) PCRF PF03462.18 EAQ85936.1 - 1.2e-48 165.6 0.1 1.2e-48 165.6 0.1 1.8 2 1 0 2 2 2 1 PCRF domain RF-1 PF00472.20 EAQ85936.1 - 4.9e-34 116.7 3.6 4.9e-34 116.7 3.6 1.7 2 0 0 2 2 2 1 RF-1 domain Peptidase_S10 PF00450.22 EAQ85937.1 - 9.6e-79 265.7 0.0 1.5e-78 265.1 0.0 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase DUF2614 PF11023.8 EAQ85937.1 - 0.065 13.3 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Zinc-ribbon containing domain DWNN PF08783.11 EAQ85939.1 - 1.1e-28 99.3 0.0 2e-28 98.4 0.0 1.5 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.6 EAQ85939.1 - 5.3e-09 35.7 6.8 1.5e-08 34.3 5.6 2.2 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC PF00098.23 EAQ85939.1 - 0.00053 19.9 0.9 0.0014 18.6 0.9 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-C3HC4_2 PF13923.6 EAQ85939.1 - 0.0057 16.5 9.8 0.0057 16.5 9.8 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-CCHC_3 PF13917.6 EAQ85939.1 - 0.03 14.3 0.5 0.069 13.1 0.5 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-RING_2 PF13639.6 EAQ85939.1 - 0.033 14.5 6.6 0.079 13.3 6.6 1.7 1 0 0 1 1 1 0 Ring finger domain zf-RING_4 PF14570.6 EAQ85939.1 - 0.079 12.8 6.6 0.21 11.4 6.6 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.6 EAQ85939.1 - 0.11 12.4 1.6 0.21 11.5 1.6 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-Nse PF11789.8 EAQ85939.1 - 0.23 11.3 6.5 0.49 10.2 6.5 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit FYVE_2 PF02318.16 EAQ85939.1 - 0.43 10.8 4.6 0.1 12.8 0.6 1.9 2 1 0 2 2 2 0 FYVE-type zinc finger zf-C3HC4_4 PF15227.6 EAQ85939.1 - 0.48 10.6 10.3 1.5 9.1 10.3 1.9 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 EAQ85939.1 - 1.7 8.6 12.8 0.14 12.2 7.1 2.0 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4 PF00097.25 EAQ85939.1 - 2.6 8.0 9.9 5.2 7.0 9.9 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) ArsA_ATPase PF02374.15 EAQ85940.1 - 4.5e-112 374.2 0.0 5.1e-112 374.0 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 EAQ85940.1 - 5.4e-13 49.2 0.3 1.7e-11 44.3 0.0 2.8 2 2 0 2 2 2 1 AAA domain CbiA PF01656.23 EAQ85940.1 - 2.7e-12 46.8 0.0 4.3e-12 46.2 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 EAQ85940.1 - 9.4e-07 28.5 0.2 0.00021 20.8 0.1 2.4 2 0 0 2 2 2 2 NUBPL iron-transfer P-loop NTPase Fer4_NifH PF00142.18 EAQ85940.1 - 5.7e-06 26.0 0.0 9.6e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.22 EAQ85940.1 - 3.9e-05 23.4 0.1 0.0016 18.1 0.0 2.5 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain CBP_BcsQ PF06564.12 EAQ85940.1 - 0.00013 21.5 0.0 0.00033 20.2 0.0 1.6 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsQ AAA_25 PF13481.6 EAQ85940.1 - 0.045 13.3 0.0 0.099 12.2 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EAQ85940.1 - 0.049 14.0 0.0 0.083 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain NB-ARC PF00931.22 EAQ85940.1 - 0.098 11.8 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_18 PF13238.6 EAQ85940.1 - 0.16 12.5 0.0 0.43 11.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain Transthyretin PF00576.21 EAQ85941.1 - 4.4e-07 30.6 0.3 6e-07 30.1 0.3 1.2 1 0 0 1 1 1 1 HIUase/Transthyretin family SecE PF00584.20 EAQ85944.1 - 1.6e-09 37.6 0.0 2.2e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex MKT1_C PF12246.8 EAQ85945.1 - 2.3e-72 243.1 0.0 3.1e-72 242.7 0.0 1.2 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.8 EAQ85945.1 - 1.2e-32 112.1 0.0 2.6e-32 111.0 0.0 1.6 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_N PF00752.17 EAQ85945.1 - 0.00078 19.9 0.0 0.026 15.0 0.0 2.6 2 0 0 2 2 2 1 XPG N-terminal domain Monellin PF09200.10 EAQ85946.1 - 0.16 11.8 0.3 0.25 11.2 0.3 1.4 1 1 0 1 1 1 0 Monellin MnmE_helical PF12631.7 EAQ85947.1 - 2.4e-29 103.0 2.5 3.1e-29 102.6 2.5 1.1 1 0 0 1 1 1 1 MnmE helical domain TrmE_N PF10396.9 EAQ85947.1 - 4.8e-22 78.4 0.0 1.1e-21 77.3 0.0 1.6 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.23 EAQ85947.1 - 1.3e-19 70.3 0.0 4.5e-19 68.6 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EAQ85947.1 - 5.4e-07 29.3 0.0 4e-06 26.4 0.0 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EAQ85947.1 - 5.1e-05 23.4 0.0 8.4e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Dynamin family RsgA_GTPase PF03193.16 EAQ85947.1 - 0.0025 17.7 0.1 0.3 11.0 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_24 PF13479.6 EAQ85947.1 - 0.0065 16.2 0.0 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain Glyco_hydro_3_C PF01915.22 EAQ85947.1 - 0.0097 15.9 0.0 0.016 15.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain ABC_tran PF00005.27 EAQ85947.1 - 0.011 16.2 0.1 0.032 14.7 0.1 1.7 1 1 0 1 1 1 0 ABC transporter Roc PF08477.13 EAQ85947.1 - 0.021 15.0 0.0 0.44 10.8 0.0 2.2 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 EAQ85947.1 - 0.1 12.1 0.0 11 5.5 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Phosphodiest PF01663.22 EAQ85947.1 - 0.19 11.3 0.1 0.3 10.6 0.1 1.2 1 0 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase Mak16 PF04874.14 EAQ85948.1 - 1e-29 103.1 14.6 1e-29 103.1 14.6 2.6 2 1 0 2 2 2 1 Mak16 protein C-terminal region Ribosomal_L28e PF01778.17 EAQ85948.1 - 2.5e-13 50.8 0.1 7.9e-13 49.2 0.1 1.8 1 0 0 1 1 1 1 Ribosomal L28e protein family BUD22 PF09073.10 EAQ85948.1 - 1.4e-07 31.2 19.5 1.8e-07 30.9 19.5 1.1 1 0 0 1 1 1 1 BUD22 TFIIA PF03153.13 EAQ85948.1 - 0.0084 16.2 12.0 0.013 15.5 12.0 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit PYC_OADA PF02436.18 EAQ85948.1 - 0.027 14.2 4.5 0.044 13.5 4.3 1.6 1 1 0 1 1 1 0 Conserved carboxylase domain Nop14 PF04147.12 EAQ85948.1 - 0.097 10.9 29.9 0.12 10.6 29.9 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 EAQ85948.1 - 8 4.6 26.1 13 3.9 26.1 1.3 1 0 0 1 1 1 0 CDC45-like protein tRNA-synt_1 PF00133.22 EAQ85949.1 - 3.2e-147 491.4 0.0 2.5e-109 366.2 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EAQ85949.1 - 1.4e-31 109.5 0.0 2.7e-31 108.6 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 EAQ85949.1 - 2.8e-09 36.2 0.0 0.027 13.2 0.0 4.0 3 1 1 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 EAQ85949.1 - 0.15 11.3 0.0 0.92 8.8 0.0 2.0 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain Mso1_Sec1_bdg PF14475.6 EAQ85950.1 - 1.2e-18 66.4 0.0 1.9e-18 65.8 0.0 1.3 1 0 0 1 1 1 1 Sec1-binding region of Mso1 RabGAP-TBC PF00566.18 EAQ85951.1 - 4.2e-37 127.9 1.4 1.1e-36 126.6 1.4 1.7 1 1 0 1 1 1 1 Rab-GTPase-TBC domain PH_RBD PF12068.8 EAQ85951.1 - 9.7e-08 31.7 0.0 2.5e-06 27.1 0.0 2.7 2 1 0 2 2 2 1 Rab-binding domain (RBD) Glyco_hydro_63 PF03200.16 EAQ85952.1 - 3e-175 583.7 1.9 9.3e-174 578.8 0.1 2.8 2 1 0 2 2 2 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 EAQ85952.1 - 4.9e-83 278.7 0.8 1.4e-82 277.2 0.1 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 63 N-terminal domain Trehalase PF01204.18 EAQ85952.1 - 9.3e-05 21.4 0.2 0.00015 20.8 0.2 1.2 1 0 0 1 1 1 1 Trehalase bZIP_2 PF07716.15 EAQ85954.1 - 0.011 15.8 8.8 0.019 15.0 8.8 1.4 1 0 0 1 1 1 0 Basic region leucine zipper bZIP_1 PF00170.21 EAQ85954.1 - 0.33 11.1 8.5 0.65 10.1 8.5 1.4 1 0 0 1 1 1 0 bZIP transcription factor Presenilin PF01080.17 EAQ85954.1 - 2.5 6.8 8.0 2.9 6.6 8.0 1.1 1 0 0 1 1 1 0 Presenilin Ndc1_Nup PF09531.10 EAQ85954.1 - 8.5 4.9 6.4 9.4 4.8 6.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup zf-ribbon_3 PF13248.6 EAQ85955.1 - 0.029 13.8 0.1 0.052 13.0 0.1 1.4 1 0 0 1 1 1 0 zinc-ribbon domain IGR PF09597.10 EAQ85956.1 - 7.8e-26 89.9 0.3 1.3e-25 89.2 0.3 1.4 1 0 0 1 1 1 1 IGR protein motif SAM_1 PF00536.30 EAQ85956.1 - 0.0025 18.2 0.0 0.005 17.2 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) MobB PF03205.14 EAQ85956.1 - 0.19 11.6 0.0 0.31 10.9 0.0 1.2 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B SNF2_N PF00176.23 EAQ85957.1 - 2.8e-63 213.8 0.0 5e-63 212.9 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-C3HC4_3 PF13920.6 EAQ85957.1 - 2.4e-09 36.9 8.9 4.8e-09 35.9 8.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EAQ85957.1 - 4.2e-09 36.6 10.3 7.8e-09 35.7 10.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EAQ85957.1 - 6.2e-09 35.6 9.4 1.3e-08 34.6 9.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EAQ85957.1 - 4e-08 33.0 9.1 7.7e-08 32.1 9.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EAQ85957.1 - 1.3e-07 31.4 7.5 2.3e-07 30.6 7.5 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 EAQ85957.1 - 1.8e-06 28.1 6.6 4.3e-06 26.9 6.6 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EAQ85957.1 - 2.2e-06 27.6 6.4 5.5e-06 26.3 6.4 1.7 1 0 0 1 1 1 1 RING-type zinc-finger Helicase_C PF00271.31 EAQ85957.1 - 5.4e-05 23.5 0.0 0.0002 21.7 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.6 EAQ85957.1 - 5.6e-05 23.0 9.6 0.00011 22.1 9.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain ResIII PF04851.15 EAQ85957.1 - 0.0022 18.0 0.0 0.0055 16.7 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4_4 PF15227.6 EAQ85957.1 - 0.039 14.1 8.6 0.082 13.1 8.6 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 EAQ85957.1 - 0.083 12.9 4.0 0.2 11.7 4.0 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger FYVE PF01363.21 EAQ85957.1 - 0.7 10.1 4.5 2.3 8.4 4.5 1.9 1 0 0 1 1 1 0 FYVE zinc finger zf-RING_4 PF14570.6 EAQ85957.1 - 1.8 8.4 4.1 5.3 6.9 4.1 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-P11 PF03854.14 EAQ85957.1 - 3.5 7.4 11.4 0.53 10.0 7.3 1.7 2 0 0 2 2 1 0 P-11 zinc finger Sec10 PF07393.11 EAQ85958.1 - 8.6e-191 636.0 0.0 1e-190 635.8 0.0 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 F-box-like PF12937.7 EAQ85958.1 - 9.2e-08 31.9 0.5 3.1e-07 30.2 0.1 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EAQ85958.1 - 1.1e-07 31.6 0.1 2.2e-07 30.6 0.1 1.5 1 0 0 1 1 1 1 F-box domain TMEM173 PF15009.6 EAQ85958.1 - 0.036 13.2 0.0 0.06 12.5 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 173 Pkinase PF00069.25 EAQ85959.1 - 6.3e-62 209.3 0.0 9.5e-62 208.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ85959.1 - 4e-32 111.5 0.0 5.3e-32 111.1 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAQ85959.1 - 0.0011 18.3 0.0 0.002 17.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Frag1 PF10277.9 EAQ85960.1 - 8.6e-19 67.9 14.6 2.7e-09 36.9 9.1 2.1 1 1 1 2 2 2 2 Frag1/DRAM/Sfk1 family Eisosome1 PF12757.7 EAQ85961.1 - 3.6e-41 140.3 15.8 3.6e-41 140.3 15.8 3.6 4 0 0 4 4 4 1 Eisosome protein 1 Ribosomal_L4 PF00573.22 EAQ85963.1 - 1.6e-37 129.1 0.9 2.1e-37 128.7 0.9 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 EAQ85963.1 - 2.8e-28 97.8 0.8 5e-28 97.0 0.1 1.8 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain Glyco_hydro_28 PF00295.17 EAQ85964.1 - 1.8e-34 119.3 6.5 2.4e-34 118.9 6.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 tRNA-synt_1g PF09334.11 EAQ85967.1 - 1e-85 287.9 0.6 1.7e-53 181.8 0.1 2.1 1 1 1 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 EAQ85967.1 - 7.7e-23 80.6 2.6 2.4e-10 39.3 0.0 3.1 2 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) Acetyltransf_3 PF13302.7 EAQ85967.1 - 2.4e-13 50.9 0.0 8.3e-13 49.2 0.0 1.9 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain tRNA-synt_1e PF01406.19 EAQ85967.1 - 2.1e-07 30.6 0.1 0.012 15.0 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain FR47 PF08445.10 EAQ85967.1 - 0.0047 16.9 0.1 3.3 7.7 0.0 2.7 2 0 0 2 2 2 2 FR47-like protein Acetyltransf_8 PF13523.6 EAQ85967.1 - 0.03 14.0 0.0 1.2 8.9 0.0 2.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Anticodon_1 PF08264.13 EAQ85967.1 - 0.13 12.2 0.0 1.2 9.1 0.0 2.2 2 0 0 2 2 2 0 Anticodon-binding domain of tRNA Acetyltransf_7 PF13508.7 EAQ85967.1 - 0.19 12.1 0.0 0.57 10.7 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PALP PF00291.25 EAQ85968.1 - 2.3e-40 138.9 0.4 3.5e-24 85.7 0.0 2.0 2 0 0 2 2 2 2 Pyridoxal-phosphate dependent enzyme DUF4719 PF15843.5 EAQ85968.1 - 0.049 13.7 0.5 0.072 13.2 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4719) DNA_pol_E_B PF04042.16 EAQ85970.1 - 5.1e-49 166.5 0.0 6.7e-49 166.1 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 EAQ85970.1 - 2.8e-38 131.0 0.0 4.5e-38 130.3 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain WD40 PF00400.32 EAQ85971.1 - 2.3e-20 72.5 12.8 1.6e-05 25.5 0.0 6.7 7 0 0 7 7 7 4 WD domain, G-beta repeat NLE PF08154.12 EAQ85971.1 - 3e-16 59.7 0.1 4.9e-16 59.0 0.1 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.8 EAQ85971.1 - 0.0008 18.2 2.3 0.072 11.7 0.8 3.0 1 1 2 3 3 3 2 Nucleoporin Nup120/160 RNA_pol_L_2 PF13656.6 EAQ85972.1 - 7.6e-20 70.5 0.1 2.6e-19 68.8 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DNA_pol_A_exo1 PF01612.20 EAQ85972.1 - 5.3e-16 58.8 0.0 9.4e-16 58.0 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease RNA_pol_L PF01193.24 EAQ85972.1 - 0.0002 20.7 0.0 0.001 18.5 0.0 2.3 2 2 0 2 2 2 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Aa_trans PF01490.18 EAQ85973.1 - 7.1e-84 281.9 32.6 8.6e-84 281.6 32.6 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF4044 PF13253.6 EAQ85973.1 - 0.47 10.0 4.4 1.1 8.8 4.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) AA_permease PF00324.21 EAQ85974.1 - 1.4e-59 202.0 30.4 1.7e-59 201.7 30.4 1.1 1 0 0 1 1 1 1 Amino acid permease SLC12 PF03522.15 EAQ85974.1 - 1.1e-24 87.2 1.4 7e-10 38.5 0.1 3.4 3 0 0 3 3 3 3 Solute carrier family 12 AA_permease_2 PF13520.6 EAQ85974.1 - 6.3e-15 54.9 36.7 9.5e-15 54.3 36.7 1.2 1 0 0 1 1 1 1 Amino acid permease cobW PF02492.19 EAQ85975.1 - 5.4e-38 130.3 0.0 1.2e-37 129.2 0.0 1.6 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.14 EAQ85975.1 - 0.0017 18.2 0.0 0.0036 17.2 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Viral_helicase1 PF01443.18 EAQ85975.1 - 0.023 14.4 0.0 0.04 13.7 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 EAQ85975.1 - 0.042 14.1 0.0 0.18 12.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF463 PF04317.12 EAQ85975.1 - 0.044 12.7 0.1 0.07 12.0 0.1 1.2 1 0 0 1 1 1 0 YcjX-like family, DUF463 TsaE PF02367.17 EAQ85975.1 - 0.078 13.0 0.1 0.15 12.1 0.1 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 EAQ85975.1 - 0.14 12.7 0.1 0.66 10.5 0.1 2.1 1 1 0 1 1 1 0 AAA domain DUF1754 PF08555.10 EAQ85977.1 - 5.1e-19 68.9 11.4 8.4e-19 68.2 11.4 1.3 1 0 0 1 1 1 1 Eukaryotic family of unknown function (DUF1754) Host_attach PF10116.9 EAQ85977.1 - 0.27 11.8 7.8 0.23 12.0 4.9 2.0 2 1 0 2 2 2 0 Protein required for attachment to host cells baeRF_family12 PF18856.1 EAQ85977.1 - 0.44 11.1 7.1 0.14 12.8 4.4 1.6 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 12 Leu_zip PF15294.6 EAQ85977.1 - 1.1 8.7 7.9 0.14 11.6 3.7 1.5 2 0 0 2 2 2 0 Leucine zipper Sigma70_ner PF04546.13 EAQ85977.1 - 2.8 7.8 8.9 2.7 7.8 8.1 1.3 1 1 0 1 1 1 0 Sigma-70, non-essential region DNA_pol_phi PF04931.13 EAQ85977.1 - 6.4 4.8 6.6 9.5 4.2 6.6 1.3 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 EAQ85977.1 - 7.4 4.7 7.7 8.4 4.6 7.7 1.2 1 0 0 1 1 1 0 CDC45-like protein CD34_antigen PF06365.12 EAQ85978.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family DUF4551 PF15087.6 EAQ85978.1 - 5.5 5.7 7.8 6.6 5.4 7.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) SRP-alpha_N PF04086.13 EAQ85978.1 - 6.5 6.6 5.5 9.5 6.0 5.5 1.4 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal ECH_2 PF16113.5 EAQ85980.1 - 1.9e-126 422.1 0.0 2.9e-126 421.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 EAQ85980.1 - 5.7e-28 97.9 0.0 1.6e-26 93.2 0.0 2.1 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase Dak1 PF02733.17 EAQ85981.1 - 2e-93 312.7 10.0 3.5e-93 311.9 10.0 1.3 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 EAQ85981.1 - 3.5e-45 154.0 0.0 1e-44 152.5 0.0 1.9 1 0 0 1 1 1 1 DAK2 domain Glyco_hydro_76 PF03663.14 EAQ85982.1 - 2.2e-158 527.6 5.6 2.5e-158 527.4 5.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 EAQ85982.1 - 0.00027 20.1 7.0 0.34 9.9 0.1 3.3 1 1 3 4 4 4 3 Glycosyl Hydrolase Family 88 NAP PF00956.18 EAQ85983.1 - 1.2e-26 93.5 9.2 1.1e-25 90.4 5.2 2.6 1 1 1 2 2 2 2 Nucleosome assembly protein (NAP) BUD22 PF09073.10 EAQ85983.1 - 0.0035 16.8 16.9 0.0053 16.2 16.9 1.2 1 0 0 1 1 1 1 BUD22 VIT1 PF01988.19 EAQ85983.1 - 0.032 14.1 2.3 4.7 7.0 1.0 2.4 2 0 0 2 2 2 0 VIT family SURF2 PF05477.11 EAQ85983.1 - 4.1 7.0 14.2 0.4 10.3 9.1 1.8 2 0 0 2 2 2 0 Surfeit locus protein 2 (SURF2) Asparaginase PF00710.20 EAQ85984.1 - 2.5e-58 196.8 0.0 4e-58 196.1 0.0 1.3 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 EAQ85984.1 - 7.4e-26 90.6 0.0 1.5e-25 89.6 0.0 1.5 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain Ank PF00023.30 EAQ85984.1 - 1.3e-09 38.0 0.8 0.0001 22.6 0.2 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 EAQ85984.1 - 6.2e-07 29.6 3.5 0.00045 20.4 0.6 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAQ85984.1 - 1.4e-06 28.7 0.1 4.9e-06 27.0 0.1 1.9 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAQ85984.1 - 1.4e-06 28.8 0.1 4.5e-06 27.1 0.1 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAQ85984.1 - 0.007 16.8 0.4 0.9 10.3 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeat BCS1_N PF08740.11 EAQ85986.1 - 8e-37 127.0 3.7 8e-37 127.0 3.7 2.9 3 1 0 3 3 3 1 BCS1 N terminal AAA PF00004.29 EAQ85986.1 - 9.8e-08 32.5 0.0 3.9e-05 24.1 0.0 3.0 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) DNA_pol_phi PF04931.13 EAQ85986.1 - 1.2 7.2 6.5 2.1 6.4 6.5 1.3 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 EAQ85986.1 - 7.2 4.8 9.2 0.073 11.3 1.3 1.6 2 0 0 2 2 2 0 CDC45-like protein Tau95_N PF17682.1 EAQ85987.1 - 2.6e-38 131.1 0.0 6.4e-38 129.8 0.0 1.7 1 0 0 1 1 1 1 Tau95 Triple barrel domain Tau95 PF09734.9 EAQ85987.1 - 5.9e-38 130.8 0.3 1.3e-37 129.7 0.3 1.6 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain B56 PF01603.20 EAQ85988.1 - 5e-144 480.3 4.8 5.2e-123 411.1 4.6 2.1 2 0 0 2 2 2 2 Protein phosphatase 2A regulatory B subunit (B56 family) Sec7_N PF12783.7 EAQ85988.1 - 0.00076 19.4 2.3 0.26 11.2 0.0 2.3 2 0 0 2 2 2 2 Guanine nucleotide exchange factor in Golgi transport N-terminal CTD_bind PF04818.13 EAQ85989.1 - 3.5e-16 59.8 0.1 7.4e-16 58.7 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase II-binding domain. DUF4748 PF15932.5 EAQ85990.1 - 0.074 12.8 0.5 0.14 11.9 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4748) Exo_endo_phos PF03372.23 EAQ85991.1 - 4.3e-10 39.5 0.1 9.9e-10 38.3 0.1 1.7 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Questin_oxidase PF14027.6 EAQ85992.1 - 1e-96 324.5 0.0 1.3e-96 324.1 0.0 1.1 1 0 0 1 1 1 1 Questin oxidase-like WD40 PF00400.32 EAQ85993.1 - 7.4e-40 134.2 28.5 1.7e-08 35.0 0.1 13.2 15 0 0 15 15 14 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAQ85993.1 - 6.3e-24 84.1 0.0 0.0066 16.7 0.0 10.2 5 2 7 12 12 11 6 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 EAQ85993.1 - 1.1e-23 83.6 0.0 1.6e-23 83.0 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family Ge1_WD40 PF16529.5 EAQ85993.1 - 7.8e-09 34.9 1.4 1.6 7.6 0.0 6.3 3 2 3 7 7 7 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 EAQ85993.1 - 1.3e-06 28.5 1.9 0.13 12.1 0.1 6.1 4 1 2 7 7 7 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 EAQ85993.1 - 1.4e-05 24.6 0.0 0.22 10.8 0.0 4.1 4 1 1 5 5 5 2 WD40-like domain Nbas_N PF15492.6 EAQ85993.1 - 0.00016 21.1 0.4 1.6 8.0 0.0 4.5 3 2 1 4 4 4 1 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 EAQ85993.1 - 0.0025 16.6 2.6 3 6.4 0.0 4.2 3 2 1 4 4 4 2 Nucleoporin Nup120/160 IKI3 PF04762.12 EAQ85993.1 - 0.0035 15.4 0.0 0.012 13.7 0.0 1.9 2 0 0 2 2 2 1 IKI3 family PD40 PF07676.12 EAQ85993.1 - 0.031 14.2 4.0 29 4.7 0.0 5.4 6 0 0 6 6 5 0 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 EAQ85993.1 - 0.032 12.8 0.1 11 4.4 0.0 3.3 2 1 1 3 3 3 0 Cytochrome D1 heme domain Utp13 PF08625.11 EAQ85993.1 - 0.083 12.8 0.3 0.21 11.5 0.3 1.8 1 1 0 1 1 1 0 Utp13 specific WD40 associated domain PQQ_3 PF13570.6 EAQ85993.1 - 0.098 13.2 0.3 62 4.3 0.0 4.3 5 0 0 5 5 4 0 PQQ-like domain PALB2_WD40 PF16756.5 EAQ85993.1 - 0.099 11.5 0.0 7 5.5 0.0 3.0 3 0 0 3 3 3 0 Partner and localizer of BRCA2 WD40 domain RPN1_RPN2_N PF17781.1 EAQ85993.1 - 0.21 11.0 0.0 0.34 10.3 0.0 1.2 1 0 0 1 1 1 0 RPN1/RPN2 N-terminal domain Septin PF00735.18 EAQ85994.1 - 4.7e-115 383.7 0.4 6.8e-115 383.2 0.4 1.2 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 EAQ85994.1 - 2.1e-07 31.0 0.0 4.2e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EAQ85994.1 - 4.8e-06 26.6 1.2 3.1e-05 23.9 0.0 2.5 3 0 0 3 3 2 1 RsgA GTPase GTP_EFTU PF00009.27 EAQ85994.1 - 5.2e-06 26.1 3.8 7.7e-05 22.3 0.1 2.6 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 EAQ85994.1 - 0.0013 19.0 0.4 0.0041 17.4 0.0 2.2 2 1 0 2 2 2 1 AAA domain Pox_A32 PF04665.12 EAQ85994.1 - 0.0026 17.3 0.1 0.0052 16.3 0.1 1.4 1 0 0 1 1 1 1 Poxvirus A32 protein Roc PF08477.13 EAQ85994.1 - 0.0035 17.5 0.1 0.0078 16.4 0.1 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AIG1 PF04548.16 EAQ85994.1 - 0.0077 15.6 0.0 0.015 14.6 0.0 1.5 1 0 0 1 1 1 1 AIG1 family IIGP PF05049.13 EAQ85994.1 - 0.0088 15.1 0.0 0.016 14.3 0.0 1.5 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) AAA_24 PF13479.6 EAQ85994.1 - 0.013 15.2 0.0 0.027 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain Ras PF00071.22 EAQ85994.1 - 0.019 14.5 0.6 0.062 12.9 0.5 1.9 2 1 0 2 2 2 0 Ras family Casc1_N PF15927.5 EAQ85994.1 - 0.034 13.8 9.6 0.092 12.4 9.6 1.7 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus KAP_NTPase PF07693.14 EAQ85994.1 - 0.034 13.4 0.0 0.046 13.0 0.0 1.5 1 1 0 1 1 1 0 KAP family P-loop domain AAA_16 PF13191.6 EAQ85994.1 - 0.036 14.4 1.6 0.089 13.2 0.1 2.4 2 1 0 2 2 2 0 AAA ATPase domain T2SSE PF00437.20 EAQ85994.1 - 0.04 13.0 0.4 0.18 10.9 0.0 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein ABC_tran PF00005.27 EAQ85994.1 - 0.05 14.1 0.1 0.2 12.2 0.0 2.0 2 0 0 2 2 2 0 ABC transporter NACHT PF05729.12 EAQ85994.1 - 0.053 13.4 0.0 0.099 12.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Sigma54_activat PF00158.26 EAQ85994.1 - 0.079 12.7 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_25 PF13481.6 EAQ85994.1 - 0.12 11.9 0.0 0.27 10.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EAQ85994.1 - 0.12 12.8 0.0 0.43 11.0 0.0 2.0 2 0 0 2 2 1 0 RNA helicase PduV-EutP PF10662.9 EAQ85994.1 - 0.14 11.9 0.4 8.3 6.2 0.1 2.6 1 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.23 EAQ85994.1 - 0.86 9.6 7.0 4.2 7.4 0.1 3.1 2 1 1 3 3 3 0 Dynamin family Ribosomal_L6e PF01159.19 EAQ85994.1 - 0.89 10.1 6.0 7.8 7.1 0.2 3.3 3 0 0 3 3 3 0 Ribosomal protein L6e FOXP-CC PF16159.5 EAQ85994.1 - 1.9 9.2 5.1 0.67 10.6 0.8 2.5 2 1 0 2 2 1 0 FOXP coiled-coil domain Myc-LZ PF02344.15 EAQ85994.1 - 2.9 8.1 10.3 4.3 7.5 4.1 3.3 2 1 0 2 2 2 0 Myc leucine zipper domain AAA_11 PF13086.6 EAQ85994.1 - 3.1 7.5 6.5 23 4.7 0.1 2.2 2 0 0 2 2 2 0 AAA domain Lge1 PF11488.8 EAQ85994.1 - 3.6 7.8 10.8 33 4.8 5.0 3.3 2 1 0 2 2 2 0 Transcriptional regulatory protein LGE1 Seryl_tRNA_N PF02403.22 EAQ85994.1 - 7 6.9 9.6 7.2 6.9 5.6 2.6 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain BCDHK_Adom3 PF10436.9 EAQ85995.1 - 7.2e-45 152.7 0.5 2.3e-44 151.1 0.0 1.9 2 0 0 2 2 2 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 EAQ85995.1 - 1.1e-06 29.1 0.0 9.2e-06 26.1 0.0 2.1 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Androgen_recep PF02166.16 EAQ85995.1 - 0.0061 15.5 0.0 0.0075 15.2 0.0 1.1 1 0 0 1 1 1 1 Androgen receptor HATPase_c_3 PF13589.6 EAQ85995.1 - 0.0065 16.3 0.0 0.014 15.2 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase USP7_ICP0_bdg PF12436.8 EAQ85996.1 - 1.4e-74 250.5 2.7 3.9e-72 242.4 1.0 3.4 3 1 0 3 3 3 2 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.6 EAQ85996.1 - 1.3e-72 243.8 6.1 1.2e-70 237.5 0.2 4.1 5 0 0 5 5 5 1 Ubiquitin-specific protease C-terminal UCH PF00443.29 EAQ85996.1 - 1.2e-41 142.9 0.5 4.3e-33 114.9 0.0 2.7 2 1 1 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EAQ85996.1 - 2.7e-20 73.2 0.1 9.7e-12 45.1 0.0 2.4 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.26 EAQ85996.1 - 4.8e-10 39.6 0.2 3.7e-09 36.7 0.1 2.5 2 0 0 2 2 2 1 MATH domain Tim17 PF02466.19 EAQ85997.1 - 2.4e-39 134.1 10.2 2.4e-39 134.1 10.2 1.5 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family Glyco_hydro_16 PF00722.21 EAQ85998.1 - 1.3e-07 31.2 0.0 2.4e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SP_C-Propep PF08999.10 EAQ85998.1 - 0.019 14.7 0.1 0.04 13.7 0.1 1.5 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide DUF4199 PF13858.6 EAQ85998.1 - 0.11 12.9 0.6 0.14 12.5 0.1 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) EphA2_TM PF14575.6 EAQ85998.1 - 0.11 13.4 0.0 0.2 12.6 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain SKIP_SNW PF02731.15 EAQ85999.1 - 2.8e-69 231.9 5.7 2.8e-69 231.9 5.7 2.2 3 0 0 3 3 3 1 SKIP/SNW domain EMP24_GP25L PF01105.24 EAQ86000.1 - 1e-46 159.2 3.7 1.1e-46 159.0 3.7 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD EssA PF10661.9 EAQ86000.1 - 0.05 13.4 0.2 0.082 12.7 0.2 1.3 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA PhoQ_Sensor PF08918.10 EAQ86000.1 - 0.11 12.3 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 PhoQ Sensor DUF3804 PF12707.7 EAQ86000.1 - 0.15 11.8 0.2 3.1 7.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3804) PhoD PF09423.10 EAQ86001.1 - 5.8e-46 157.1 0.0 9.9e-46 156.3 0.0 1.3 1 0 0 1 1 1 1 PhoD-like phosphatase TauD PF02668.16 EAQ86001.1 - 1.7e-33 116.6 0.0 2.9e-33 115.8 0.0 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 EAQ86001.1 - 0.0026 16.9 0.0 0.0062 15.7 0.0 1.5 1 0 0 1 1 1 1 CsiD POPLD PF08170.12 EAQ86001.1 - 0.078 13.3 0.0 0.22 11.9 0.0 1.8 1 0 0 1 1 1 0 POPLD (NUC188) domain adh_short_C2 PF13561.6 EAQ86002.1 - 6.6e-52 176.4 1.5 3.4e-51 174.1 1.5 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EAQ86002.1 - 9.1e-30 103.6 1.5 1.1e-20 73.9 0.2 2.0 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 EAQ86002.1 - 3.4e-08 33.6 0.1 2.8e-07 30.6 0.0 2.0 2 0 0 2 2 2 1 KR domain 3HCDH_N PF02737.18 EAQ86002.1 - 0.00079 19.4 0.2 0.0014 18.6 0.2 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 EAQ86002.1 - 0.0015 17.9 0.1 0.0041 16.5 0.1 1.6 1 1 1 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 EAQ86002.1 - 0.0019 18.2 0.2 0.0037 17.3 0.2 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus PALP PF00291.25 EAQ86002.1 - 0.0028 17.1 0.3 0.0048 16.4 0.3 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme F420_oxidored PF03807.17 EAQ86002.1 - 0.0028 18.2 0.4 0.0061 17.1 0.4 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.21 EAQ86002.1 - 0.023 14.2 0.1 0.61 9.5 0.0 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 EAQ86002.1 - 0.038 14.1 0.0 0.067 13.2 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 EAQ86002.1 - 0.13 12.6 0.5 0.2 11.9 0.1 1.5 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Metallophos PF00149.28 EAQ86003.1 - 6.3e-38 131.3 0.1 1e-37 130.7 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Ribosomal_L27A PF00828.19 EAQ86004.1 - 4e-20 72.8 0.0 7e-20 72.0 0.0 1.4 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A HA2 PF04408.23 EAQ86005.1 - 8.4e-25 87.2 0.4 3.1e-24 85.3 0.0 2.2 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EAQ86005.1 - 1e-11 45.2 0.0 1e-10 41.9 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 EAQ86005.1 - 6.7e-10 39.2 0.0 1.4e-09 38.2 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 EAQ86005.1 - 2.3e-09 37.2 0.0 7.3e-09 35.6 0.1 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_30 PF13604.6 EAQ86005.1 - 1.5e-05 24.8 0.1 9e-05 22.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EAQ86005.1 - 0.0002 21.7 0.0 0.00073 19.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAQ86005.1 - 0.0021 18.4 0.0 0.005 17.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 EAQ86005.1 - 0.0031 17.0 0.1 0.036 13.5 0.0 2.1 2 0 0 2 2 2 1 PhoH-like protein T2SSE PF00437.20 EAQ86005.1 - 0.0083 15.2 0.0 0.016 14.3 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein DUF2075 PF09848.9 EAQ86005.1 - 0.014 14.7 0.0 0.027 13.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_23 PF13476.6 EAQ86005.1 - 0.053 14.0 6.0 0.084 13.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain Med6 PF04934.14 EAQ86006.1 - 1.8e-13 50.4 0.0 2.3e-13 50.1 0.0 1.1 1 0 0 1 1 1 1 MED6 mediator sub complex component MMtag PF10159.9 EAQ86007.1 - 1.7e-30 105.1 1.7 1.7e-30 105.1 1.7 2.8 3 0 0 3 3 3 1 Multiple myeloma tumor-associated DUF3684 PF12449.8 EAQ86008.1 - 0 1417.1 0.0 0 1409.2 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF3684) HATPase_c_3 PF13589.6 EAQ86008.1 - 2.4e-05 24.2 0.0 6.3e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 2-Hacid_dh_C PF02826.19 EAQ86009.1 - 3.3e-51 173.2 0.0 5.7e-51 172.4 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EAQ86009.1 - 6.1e-16 58.3 0.0 8.6e-16 57.8 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EAQ86009.1 - 0.00017 21.8 0.0 0.00073 19.7 0.0 1.9 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase AA_permease_2 PF13520.6 EAQ86010.1 - 4.4e-60 203.7 36.0 5.9e-60 203.3 36.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EAQ86010.1 - 2.7e-27 95.5 24.0 2.7e-27 95.5 24.0 2.0 2 0 0 2 2 2 1 Amino acid permease PsbN PF02468.15 EAQ86010.1 - 9.8 6.1 6.1 14 5.6 0.0 3.3 3 0 0 3 3 3 0 Photosystem II reaction centre N protein (psbN) tRNA-synt_1 PF00133.22 EAQ86011.1 - 2.4e-50 171.4 0.0 7.1e-17 60.9 0.1 6.0 2 1 3 5 5 5 5 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.6 EAQ86011.1 - 4.6e-40 137.1 0.0 9.9e-40 136.0 0.0 1.6 1 1 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.11 EAQ86011.1 - 2.1e-28 99.2 0.0 1.1e-19 70.5 0.0 4.3 3 1 1 4 4 4 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 EAQ86011.1 - 1.1e-09 38.5 0.0 2.1e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 EAQ86011.1 - 0.036 13.4 0.0 5.8 6.2 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain UvrD_C_2 PF13538.6 EAQ86012.1 - 5.3e-05 23.0 0.0 0.00041 20.1 0.0 2.3 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.14 EAQ86012.1 - 0.00035 18.7 0.0 0.00049 18.2 0.0 1.1 1 0 0 1 1 1 1 Helicase PIF1 PF05970.14 EAQ86012.1 - 0.00042 19.6 0.0 0.00058 19.1 0.0 1.3 1 0 0 1 1 1 1 PIF1-like helicase EF-hand_1 PF00036.32 EAQ86013.1 - 9.2e-28 93.7 10.1 1.7e-07 30.3 0.2 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EAQ86013.1 - 5.4e-24 84.4 10.2 5.4e-14 52.4 0.4 2.7 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 EAQ86013.1 - 2.4e-20 70.6 6.2 9.3e-05 22.1 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 EAQ86013.1 - 6e-19 66.6 9.5 1.2e-06 27.7 0.3 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 EAQ86013.1 - 6.8e-14 51.5 9.4 0.00017 21.4 0.3 4.3 2 1 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EAQ86013.1 - 1.2e-06 28.9 0.0 0.0036 17.6 0.0 2.3 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 EAQ86013.1 - 5.9e-06 26.2 8.3 0.0097 15.8 0.4 3.9 1 1 3 4 4 4 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 EAQ86013.1 - 0.01 16.2 0.1 0.53 10.6 0.0 2.6 2 1 1 3 3 3 1 EF-hand domain Dockerin_1 PF00404.18 EAQ86013.1 - 0.011 15.9 1.3 0.086 13.0 1.5 2.4 1 1 1 2 2 2 0 Dockerin type I domain EPL1 PF10513.9 EAQ86014.1 - 7.2e-06 26.5 0.6 7.2e-06 26.5 0.6 3.3 2 2 0 2 2 2 1 Enhancer of polycomb-like Erythro_esteras PF05139.14 EAQ86014.1 - 0.0052 16.6 0.7 0.0086 15.9 0.7 1.5 1 0 0 1 1 1 1 Erythromycin esterase DUF3952 PF13130.6 EAQ86014.1 - 0.013 15.6 0.0 0.048 13.8 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3952) Peptidase_M22 PF00814.25 EAQ86015.1 - 1.5e-83 280.6 0.0 1.8e-83 280.4 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family Carbam_trans_N PF02543.15 EAQ86015.1 - 0.13 11.9 0.0 1.1 8.9 0.0 2.0 2 0 0 2 2 2 0 Carbamoyltransferase N-terminus AMPK1_CBM PF16561.5 EAQ86016.1 - 2.5e-27 94.9 0.1 4.7e-27 94.0 0.1 1.5 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase AMPKBI PF04739.15 EAQ86016.1 - 6.8e-26 90.3 2.3 6.8e-26 90.3 2.3 2.5 2 0 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interaction domain Spt4 PF06093.13 EAQ86017.1 - 7.1e-33 112.5 0.2 8.6e-33 112.3 0.2 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger Coronavirus_5 PF05528.11 EAQ86017.1 - 0.19 11.7 0.3 1.1 9.3 0.1 1.9 1 1 1 2 2 2 0 Coronavirus gene 5 protein Kin17_mid PF10357.9 EAQ86018.1 - 5.6e-46 155.6 2.1 1.1e-45 154.6 2.1 1.5 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein zf-C2H2_jaz PF12171.8 EAQ86018.1 - 3.8e-05 23.9 4.4 8.6e-05 22.7 4.4 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EAQ86018.1 - 4e-05 23.8 4.0 7e-05 23.1 4.0 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 EAQ86018.1 - 0.0011 19.3 1.0 0.0026 18.0 1.0 1.6 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) AA_kinase PF00696.28 EAQ86019.1 - 1.6e-36 126.1 0.1 3.8e-36 124.9 0.0 1.7 2 0 0 2 2 2 1 Amino acid kinase family ACT PF01842.25 EAQ86019.1 - 7.5e-15 54.4 1.5 2.1e-08 33.8 0.1 2.7 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.6 EAQ86019.1 - 5.2e-13 48.6 4.4 1.2e-09 37.8 0.2 2.5 2 0 0 2 2 2 2 ACT domain CBM_17_28 PF03424.14 EAQ86019.1 - 0.093 12.4 0.1 0.16 11.7 0.1 1.4 1 0 0 1 1 1 0 Carbohydrate binding domain (family 17/28) ABC_tran PF00005.27 EAQ86020.1 - 8.4e-14 52.3 0.0 2.6e-13 50.7 0.0 1.8 2 1 0 2 2 2 1 ABC transporter SMC_N PF02463.19 EAQ86020.1 - 0.00064 19.2 0.0 0.00092 18.7 0.0 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 EAQ86020.1 - 0.017 13.9 0.2 0.02 13.7 0.2 1.1 1 0 0 1 1 1 0 Predicted ATPase of the ABC class SbcCD_C PF13558.6 EAQ86020.1 - 0.048 13.9 4.7 0.47 10.7 2.2 2.9 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit CTD_bind PF04818.13 EAQ86021.1 - 5.1e-12 46.4 0.3 1.2e-10 42.1 0.0 2.5 2 0 0 2 2 2 1 RNA polymerase II-binding domain. MCD_N PF17408.2 EAQ86021.1 - 0.008 16.3 0.6 0.024 14.7 0.3 2.0 2 0 0 2 2 2 1 Malonyl-CoA decarboxylase N-terminal domain CREPT PF16566.5 EAQ86021.1 - 0.01 16.0 0.5 0.055 13.6 0.1 2.4 3 0 0 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour HOIP-UBA PF16678.5 EAQ86021.1 - 0.057 13.4 0.3 0.12 12.4 0.2 1.5 1 1 0 1 1 1 0 HOIP UBA domain pair DUF4407 PF14362.6 EAQ86021.1 - 0.082 12.3 1.6 0.12 11.7 1.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Clathrin_lg_ch PF01086.17 EAQ86022.1 - 2.9e-80 269.6 3.7 3.3e-80 269.5 3.7 1.0 1 0 0 1 1 1 1 Clathrin light chain DUF4407 PF14362.6 EAQ86022.1 - 1.1 8.6 5.1 1.8 7.9 5.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SNARE PF05739.19 EAQ86023.1 - 2.4e-15 56.2 0.4 2.4e-15 56.2 0.4 2.3 3 0 0 3 3 3 1 SNARE domain COX7a PF02238.15 EAQ86023.1 - 9.9e-12 45.1 0.7 2.8e-11 43.6 0.7 1.8 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VII Syntaxin PF00804.25 EAQ86023.1 - 0.012 15.3 0.6 0.012 15.3 0.6 2.5 3 0 0 3 3 3 0 Syntaxin MCPsignal PF00015.21 EAQ86023.1 - 0.042 13.7 5.4 0.15 11.9 0.7 2.7 2 1 1 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DNA_repr_REX1B PF14966.6 EAQ86023.1 - 0.17 12.5 0.0 0.17 12.5 0.0 3.2 2 1 1 3 3 3 0 DNA repair REX1-B TMPIT PF07851.13 EAQ86023.1 - 0.52 9.5 6.2 0.31 10.2 3.2 2.0 1 1 1 2 2 2 0 TMPIT-like protein EF-hand_1 PF00036.32 EAQ86024.1 - 1.1e-41 137.3 12.9 7.8e-10 37.6 0.9 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EAQ86024.1 - 3.5e-36 123.5 5.8 3.9e-19 68.9 2.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 EAQ86024.1 - 6.8e-35 118.7 11.4 2.3e-15 56.1 0.6 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 EAQ86024.1 - 2.1e-30 102.0 9.5 1.9e-09 36.7 0.2 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 EAQ86024.1 - 6.5e-26 88.6 10.6 2.6e-06 26.7 0.3 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 EAQ86024.1 - 1.5e-16 60.5 0.4 2.3e-09 37.4 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 EAQ86024.1 - 3.4e-09 36.6 1.9 0.00075 19.4 0.2 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 EAQ86024.1 - 5.6e-09 36.3 0.2 0.0016 18.7 0.1 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.13 EAQ86024.1 - 9.9e-07 28.7 0.0 0.0077 16.2 0.0 3.0 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.10 EAQ86024.1 - 5.8e-06 26.3 1.6 2.3e-05 24.4 0.2 2.3 2 1 0 2 2 2 1 Ca2+ insensitive EF hand EF-hand_11 PF08976.11 EAQ86024.1 - 9.1e-05 23.3 0.2 0.0022 18.8 0.1 2.0 1 1 1 2 2 2 1 EF-hand domain TerB PF05099.13 EAQ86024.1 - 0.00012 22.0 0.3 0.35 10.8 0.0 2.2 1 1 1 2 2 2 2 Tellurite resistance protein TerB Caleosin PF05042.13 EAQ86024.1 - 0.00045 20.2 1.8 0.44 10.5 0.0 3.5 1 1 3 4 4 4 1 Caleosin related protein RNA_pol_Rpb4 PF03874.16 EAQ86024.1 - 0.00062 20.1 0.8 0.66 10.3 0.1 2.7 2 1 1 3 3 3 2 RNA polymerase Rpb4 DUF3349 PF11829.8 EAQ86024.1 - 0.0014 19.3 0.4 3.7 8.4 0.0 2.9 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) Dockerin_1 PF00404.18 EAQ86024.1 - 0.0053 16.9 7.0 0.38 11.0 0.8 2.9 1 1 2 3 3 3 2 Dockerin type I domain DUF5580 PF17743.1 EAQ86024.1 - 0.006 15.2 0.0 0.0062 15.1 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5580) SurA_N_2 PF13623.6 EAQ86024.1 - 0.0091 15.9 0.9 0.32 10.9 0.1 2.2 1 1 1 2 2 2 1 SurA N-terminal domain EF-hand_14 PF17959.1 EAQ86024.1 - 0.012 16.0 0.5 6.2 7.2 0.1 2.4 1 1 1 2 2 2 0 EF-hand domain Poly_export PF02563.16 EAQ86024.1 - 0.023 14.9 0.0 0.18 12.1 0.0 2.5 2 1 0 2 2 2 0 Polysaccharide biosynthesis/export protein DUF4497 PF14924.6 EAQ86024.1 - 0.036 14.5 0.0 8.7 6.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4497) RuvA_C PF07499.13 EAQ86024.1 - 0.058 13.9 0.1 8.5 6.9 0.0 3.0 3 0 0 3 3 3 0 RuvA, C-terminal domain MotA_activ PF09114.10 EAQ86024.1 - 0.061 13.4 0.3 1.2 9.3 0.0 2.3 1 1 0 2 2 2 0 Transcription factor MotA, activation domain dCache_2 PF08269.11 EAQ86024.1 - 0.066 12.4 0.1 1.1 8.4 0.1 2.1 1 1 1 2 2 2 0 Cache domain DUF5132 PF17195.4 EAQ86024.1 - 0.15 12.2 0.5 21 5.3 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF5132) RloB PF13707.6 EAQ86024.1 - 0.16 12.2 1.1 0.76 9.9 0.2 2.0 1 1 1 2 2 2 0 RloB-like protein Adaptin_N PF01602.20 EAQ86025.1 - 1.4e-137 459.4 3.1 1.7e-137 459.1 3.1 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EAQ86025.1 - 3e-07 30.6 9.6 0.00025 21.1 0.1 3.9 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EAQ86025.1 - 7.2e-07 29.5 0.7 0.061 13.7 0.0 3.5 2 2 1 3 3 3 2 HEAT repeats DUF3730 PF12530.8 EAQ86025.1 - 2.6e-05 23.9 0.3 0.0015 18.2 0.0 2.6 1 1 1 2 2 2 1 Protein of unknown function (DUF3730) HEAT PF02985.22 EAQ86025.1 - 0.0027 17.8 2.4 5.6 7.5 0.1 4.6 4 1 1 5 5 5 1 HEAT repeat RIX1 PF08167.12 EAQ86025.1 - 0.026 14.3 1.2 0.61 9.8 0.0 3.3 3 1 0 3 3 3 0 rRNA processing/ribosome biogenesis Arm PF00514.23 EAQ86025.1 - 0.059 13.4 0.7 69 3.7 0.1 5.1 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat RICTOR_M PF14666.6 EAQ86025.1 - 0.069 12.9 0.5 0.41 10.4 0.0 2.5 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, middle domain Cohesin_HEAT PF12765.7 EAQ86025.1 - 0.19 12.1 0.9 0.48 10.8 0.2 2.2 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion RRP36 PF06102.12 EAQ86026.1 - 2.4e-56 190.3 22.6 2.4e-56 190.3 22.6 1.8 2 0 0 2 2 2 1 rRNA biogenesis protein RRP36 ABC1 PF03109.16 EAQ86027.1 - 7.3e-33 113.3 0.0 1.4e-32 112.3 0.0 1.5 1 0 0 1 1 1 1 ABC1 family Pkinase PF00069.25 EAQ86027.1 - 0.14 11.5 0.0 0.68 9.2 0.0 2.0 2 0 0 2 2 2 0 Protein kinase domain Es2 PF09751.9 EAQ86028.1 - 1.7e-109 367.5 9.3 2.2e-55 189.1 0.4 2.1 2 0 0 2 2 2 2 Nuclear protein Es2 Hus1 PF04005.12 EAQ86029.1 - 3e-82 276.0 0.0 4.2e-82 275.5 0.0 1.2 1 0 0 1 1 1 1 Hus1-like protein zf-RING_2 PF13639.6 EAQ86029.1 - 1.1e-07 32.1 1.7 1.1e-07 32.1 1.7 1.9 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 EAQ86029.1 - 4.8e-06 26.3 1.4 4.8e-06 26.3 1.4 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EAQ86029.1 - 1.5e-05 24.9 1.6 4.1e-05 23.5 1.6 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EAQ86029.1 - 2.3e-05 24.1 1.7 7.4e-05 22.5 1.7 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EAQ86029.1 - 9.5e-05 22.6 0.7 0.00023 21.4 0.7 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 EAQ86029.1 - 0.00011 22.0 2.4 0.00011 22.0 2.4 2.5 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EAQ86029.1 - 0.00057 20.0 0.3 0.0017 18.5 0.3 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 EAQ86029.1 - 0.0033 17.4 0.2 0.0033 17.4 0.2 2.8 3 0 0 3 3 3 1 RING-type zinc-finger zf-RING_11 PF17123.5 EAQ86029.1 - 0.015 15.0 0.2 0.015 15.0 0.2 3.0 3 1 0 3 3 3 0 RING-like zinc finger zf-ANAPC11 PF12861.7 EAQ86029.1 - 0.016 15.3 0.3 0.028 14.4 0.3 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 EAQ86029.1 - 0.017 15.0 0.9 0.05 13.5 0.9 1.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 PhoR PF11808.8 EAQ86029.1 - 0.096 13.1 0.0 0.23 11.9 0.0 1.6 1 0 0 1 1 1 0 Phosphate regulon sensor protein PhoR zf-RING_4 PF14570.6 EAQ86029.1 - 0.12 12.2 1.7 0.33 10.8 1.7 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Sec16_C PF12931.7 EAQ86030.1 - 1e-109 366.9 0.0 1.6e-109 366.2 0.0 1.3 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.7 EAQ86030.1 - 5.4e-25 88.3 0.0 1.8e-24 86.6 0.0 1.9 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region PhoLip_ATPase_C PF16212.5 EAQ86031.1 - 1.1e-49 169.5 7.6 1.1e-49 169.5 7.6 2.0 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EAQ86031.1 - 3.5e-16 58.7 0.8 8.6e-16 57.4 0.5 1.8 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 EAQ86031.1 - 5.8e-14 52.9 1.0 2.2e-07 31.4 1.0 3.4 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EAQ86031.1 - 5e-05 23.3 0.0 0.0023 18.0 0.0 2.9 2 1 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 EAQ86031.1 - 0.00088 18.8 10.2 0.0068 15.9 0.0 3.1 4 0 0 4 4 4 2 E1-E2 ATPase Hydrolase_3 PF08282.12 EAQ86031.1 - 0.0014 18.4 0.0 0.0025 17.6 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Ribosomal_S9 PF00380.19 EAQ86035.1 - 9.3e-42 142.4 0.3 1.6e-41 141.6 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein S9/S16 EF1G PF00647.19 EAQ86036.1 - 3.6e-45 152.4 0.2 9.4e-45 151.1 0.1 1.8 2 0 0 2 2 2 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.25 EAQ86036.1 - 6.6e-15 55.1 0.0 1.4e-14 54.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EAQ86036.1 - 5.1e-13 49.2 0.1 2.6e-12 46.9 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EAQ86036.1 - 1.1e-11 44.6 0.0 2.5e-11 43.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EAQ86036.1 - 2e-06 28.1 0.0 4.8e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EAQ86036.1 - 7.5e-05 22.9 0.0 0.00017 21.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EAQ86036.1 - 0.0011 19.2 0.0 0.0037 17.5 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain NIF PF03031.18 EAQ86037.1 - 1.2e-17 64.1 0.0 6.6e-17 61.7 0.0 1.9 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase RNA_capsid PF03035.14 EAQ86037.1 - 0.25 11.3 5.2 6.5 6.7 0.4 3.0 2 1 1 3 3 3 0 Calicivirus putative RNA polymerase/capsid protein DUF3455 PF11937.8 EAQ86038.1 - 1e-35 123.4 0.1 1.4e-35 123.1 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) DUF2990 PF11693.8 EAQ86038.1 - 7.2e-07 29.3 0.6 1.9e-06 27.9 0.6 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF2990) CASP_C PF08172.12 EAQ86039.1 - 4.6e-17 62.2 23.9 6.1e-07 29.0 0.0 4.5 4 0 0 4 4 4 3 CASP C terminal Cep57_MT_bd PF06657.13 EAQ86039.1 - 0.0015 18.9 25.1 0.082 13.4 1.7 5.0 5 0 0 5 5 5 2 Centrosome microtubule-binding domain of Cep57 SKA1 PF07160.12 EAQ86039.1 - 0.0025 17.7 16.4 0.17 11.7 7.5 2.9 2 1 0 2 2 2 2 Spindle and kinetochore-associated protein 1 ERM PF00769.19 EAQ86039.1 - 0.0029 17.5 3.2 0.0029 17.5 3.2 3.2 3 1 0 3 3 3 1 Ezrin/radixin/moesin family Fez1 PF06818.15 EAQ86039.1 - 0.03 14.8 1.1 0.03 14.8 1.1 3.7 2 1 1 3 3 3 0 Fez1 CREPT PF16566.5 EAQ86039.1 - 0.037 14.2 18.9 0.74 10.0 7.2 3.7 3 1 0 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour Tropomyosin_1 PF12718.7 EAQ86039.1 - 0.13 12.4 49.1 0.42 10.7 17.4 4.7 3 2 1 4 4 4 0 Tropomyosin like DivIC PF04977.15 EAQ86039.1 - 0.72 9.7 0.0 0.72 9.7 0.0 6.9 6 3 1 8 8 8 0 Septum formation initiator betaPIX_CC PF16523.5 EAQ86039.1 - 0.78 9.6 12.4 0.22 11.4 2.6 3.2 2 1 0 2 2 2 0 betaPIX coiled coil DUF4349 PF14257.6 EAQ86039.1 - 1 8.8 26.7 0.086 12.3 3.8 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4349) PI3K_P85_iSH2 PF16454.5 EAQ86039.1 - 1.3 8.6 28.0 0.24 11.0 0.8 4.2 2 1 2 4 4 4 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain TPR_MLP1_2 PF07926.12 EAQ86039.1 - 6 6.9 54.4 0.87 9.7 8.6 5.9 4 2 2 6 6 6 0 TPR/MLP1/MLP2-like protein ATG16 PF08614.11 EAQ86039.1 - 6.3 7.0 55.2 0.63 10.2 11.3 5.3 3 1 2 5 5 5 0 Autophagy protein 16 (ATG16) FlaC_arch PF05377.11 EAQ86039.1 - 7 7.1 23.5 5.2 7.5 0.3 5.8 4 1 0 5 5 5 0 Flagella accessory protein C (FlaC) APG6_N PF17675.1 EAQ86039.1 - 8.5 6.9 50.5 0.97 10.0 13.4 4.5 1 1 3 4 4 4 0 Apg6 coiled-coil region UPF0242 PF06785.11 EAQ86039.1 - 9.9 6.2 38.5 1.1 9.4 4.1 4.8 2 1 2 4 4 4 0 Uncharacterised protein family (UPF0242) N-terminus Vps39_2 PF10367.9 EAQ86040.1 - 0.00014 22.3 0.0 0.0003 21.2 0.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.9 EAQ86040.1 - 0.17 12.2 0.0 0.81 10.0 0.0 2.2 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 Dicty_CAR PF05462.11 EAQ86041.1 - 7.1e-07 28.7 11.2 7.1e-07 28.7 11.2 2.1 2 1 0 2 2 2 1 Slime mold cyclic AMP receptor Git3 PF11710.8 EAQ86041.1 - 0.00031 20.6 10.7 0.00058 19.7 10.7 1.5 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Spt20 PF12090.8 EAQ86041.1 - 0.024 14.3 4.4 0.035 13.7 4.4 1.3 1 0 0 1 1 1 0 Spt20 family Plasmodium_Vir PF05795.11 EAQ86041.1 - 0.28 10.6 0.2 0.41 10.0 0.2 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Ndc1_Nup PF09531.10 EAQ86041.1 - 3.8 6.1 10.4 8.4 4.9 4.7 2.4 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup Mucin PF01456.17 EAQ86041.1 - 8.5 6.4 20.7 24 4.9 20.7 1.7 1 0 0 1 1 1 0 Mucin-like glycoprotein Cyclin_N2 PF16500.5 EAQ86042.1 - 0.033 14.9 1.3 0.092 13.5 1.3 1.7 1 0 0 1 1 1 0 N-terminal region of cyclin_N Xan_ur_permease PF00860.20 EAQ86043.1 - 8.5e-26 90.6 27.5 3.8e-24 85.1 27.4 2.2 1 1 0 1 1 1 1 Permease family PY_rept_46 PF09689.10 EAQ86043.1 - 0.08 13.5 1.5 0.18 12.4 1.5 1.5 1 0 0 1 1 1 0 Plasmodium yoelii repeat (PY_rept_46) Peptidase_C12 PF01088.21 EAQ86044.1 - 3.7e-65 219.6 0.0 4.5e-65 219.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 EAQ86044.1 - 5.5e-10 39.0 0.1 1.3e-09 37.8 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases Ribosomal_L22 PF00237.19 EAQ86045.1 - 5e-41 139.1 0.0 7e-41 138.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e LTD PF00932.19 EAQ86045.1 - 0.17 12.2 0.0 0.23 11.8 0.0 1.4 1 1 0 1 1 1 0 Lamin Tail Domain Fibrillarin PF01269.17 EAQ86046.1 - 2.3e-93 311.5 0.0 2.9e-93 311.2 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 EAQ86046.1 - 3e-06 27.1 0.0 4.3e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 EAQ86046.1 - 0.0094 15.7 0.1 0.014 15.2 0.1 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltr_RsmB-F PF01189.17 EAQ86046.1 - 0.03 14.0 0.0 0.054 13.1 0.0 1.4 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F zf-C2H2 PF00096.26 EAQ86049.1 - 0.0024 18.2 14.7 0.39 11.3 0.8 4.2 4 0 0 4 4 4 3 Zinc finger, C2H2 type TOC159_MAD PF11886.8 EAQ86049.1 - 0.0036 16.3 0.2 0.0057 15.6 0.2 1.2 1 0 0 1 1 1 1 Translocase of chloroplast 159/132, membrane anchor domain zf-TAZ PF02135.16 EAQ86049.1 - 0.26 11.8 2.7 0.55 10.7 0.9 2.1 2 0 0 2 2 2 0 TAZ zinc finger zf-C2H2_4 PF13894.6 EAQ86049.1 - 1.8 9.6 18.3 1.8 9.6 0.6 4.4 4 1 0 4 4 4 0 C2H2-type zinc finger FOXP-CC PF16159.5 EAQ86049.1 - 4.1 8.1 5.0 24 5.7 0.5 3.0 3 0 0 3 3 3 0 FOXP coiled-coil domain Methyltransf_16 PF10294.9 EAQ86050.1 - 1.6e-10 41.0 0.0 2.4e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 EAQ86050.1 - 0.001 18.6 0.0 0.0016 17.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) zf-rbx1 PF12678.7 EAQ86052.1 - 1.3e-09 38.2 5.2 2.2e-09 37.4 5.2 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 EAQ86052.1 - 5.3e-09 36.3 5.6 1e-08 35.3 5.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EAQ86052.1 - 7.3e-06 25.8 3.1 1.3e-05 25.0 3.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EAQ86052.1 - 2.7e-05 24.0 1.7 7.2e-05 22.7 1.9 1.6 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EAQ86052.1 - 6.7e-05 22.7 7.0 0.00097 19.0 7.4 2.1 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EAQ86052.1 - 0.00011 22.1 1.7 0.00022 21.2 1.7 1.5 1 0 0 1 1 1 1 RING-type zinc-finger Zn_ribbon_17 PF17120.5 EAQ86052.1 - 0.00052 19.6 1.2 0.0011 18.5 1.2 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 EAQ86052.1 - 0.00078 19.3 2.6 0.0017 18.1 2.6 1.6 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 EAQ86052.1 - 0.00088 19.3 0.5 0.0018 18.3 0.5 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 EAQ86052.1 - 0.0051 16.6 7.2 0.012 15.4 7.2 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EAQ86052.1 - 0.12 12.1 2.3 1.2 9.0 2.3 2.2 1 1 0 1 1 1 0 RING-like zinc finger zf-RING_4 PF14570.6 EAQ86052.1 - 0.82 9.5 3.0 2 8.3 3.1 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 EAQ86052.1 - 7 6.9 5.2 6.5 7.0 3.0 2.1 2 1 0 2 2 2 0 FANCL C-terminal domain APC_u15 PF16636.5 EAQ86053.1 - 8 7.0 6.0 61 4.2 0.5 3.6 3 0 0 3 3 3 0 Unstructured region on APC between APC_crr regions 5 and 6 TPR_2 PF07719.17 EAQ86054.1 - 0.001 19.0 4.0 0.25 11.6 0.0 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 EAQ86054.1 - 0.0025 17.5 2.6 0.11 12.4 0.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EAQ86054.1 - 0.0048 17.1 1.8 0.14 12.4 0.6 2.4 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 SRP_TPR_like PF17004.5 EAQ86054.1 - 0.01 15.8 0.1 0.019 15.0 0.1 1.4 1 0 0 1 1 1 0 Putative TPR-like repeat TPR_7 PF13176.6 EAQ86054.1 - 0.026 14.5 0.2 0.29 11.3 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 EAQ86054.1 - 0.031 14.6 1.8 1.2 9.5 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Cob_adeno_trans PF01923.18 EAQ86054.1 - 0.084 13.0 0.4 0.18 12.0 0.4 1.5 1 0 0 1 1 1 0 Cobalamin adenosyltransferase TPR_16 PF13432.6 EAQ86054.1 - 9.5 7.0 0.0 9.5 7.0 0.0 4.4 5 1 0 5 5 5 0 Tetratricopeptide repeat MPS2 PF17060.5 EAQ86055.1 - 0.055 12.7 0.2 0.11 11.8 0.2 1.4 1 0 0 1 1 1 0 Monopolar spindle protein 2 FAD_binding_1 PF00667.20 EAQ86057.1 - 3.1e-45 154.5 0.0 4.4e-45 154.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 EAQ86057.1 - 4.8e-10 40.0 0.0 1.8e-09 38.2 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Nitroreductase PF00881.24 EAQ86058.1 - 8.5e-15 55.2 0.1 1.1e-14 54.9 0.1 1.1 1 0 0 1 1 1 1 Nitroreductase family PS_Dcarbxylase PF02666.15 EAQ86059.1 - 1.1e-59 201.4 0.0 2.2e-56 190.6 0.0 2.1 2 0 0 2 2 2 2 Phosphatidylserine decarboxylase Biotin_lipoyl_2 PF13533.6 EAQ86059.1 - 0.0059 16.4 0.1 0.012 15.4 0.1 1.4 1 0 0 1 1 1 1 Biotin-lipoyl like Cyt_b-c1_8 PF10890.8 EAQ86059.1 - 0.039 14.4 0.1 1 9.8 0.0 2.4 2 0 0 2 2 2 0 Cytochrome b-c1 complex subunit 8 Biotin_lipoyl PF00364.22 EAQ86059.1 - 0.2 11.5 0.1 0.37 10.7 0.1 1.4 1 0 0 1 1 1 0 Biotin-requiring enzyme ubiquitin PF00240.23 EAQ86060.1 - 8.3e-06 25.5 1.3 1e-05 25.2 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin family DUF2407 PF10302.9 EAQ86060.1 - 3.7e-05 24.2 3.2 0.00013 22.5 0.1 2.7 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain Presenilin PF01080.17 EAQ86060.1 - 0.0017 17.2 2.8 0.0017 17.2 2.8 2.1 2 0 0 2 2 2 1 Presenilin Pex14_N PF04695.13 EAQ86060.1 - 0.0032 18.1 1.1 0.0032 18.1 1.1 4.9 4 1 1 5 5 5 1 Peroxisomal membrane anchor protein (Pex14p) conserved region RskA PF10099.9 EAQ86060.1 - 0.0046 17.3 7.7 0.0046 17.3 7.7 4.1 3 1 1 4 4 4 1 Anti-sigma-K factor rskA PepSY_TM PF03929.16 EAQ86060.1 - 0.035 13.8 0.2 0.035 13.8 0.2 4.0 3 1 1 4 4 4 0 PepSY-associated TM region DUF4834 PF16118.5 EAQ86060.1 - 0.081 13.9 0.4 0.081 13.9 0.4 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) adh_short_C2 PF13561.6 EAQ86061.1 - 1.4e-43 149.1 2.2 1.9e-43 148.7 2.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EAQ86061.1 - 2e-40 138.4 1.3 2.1e-40 138.3 0.2 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 EAQ86061.1 - 5.6e-11 42.7 1.2 9.4e-11 41.9 1.2 1.3 1 0 0 1 1 1 1 KR domain N2227 PF07942.12 EAQ86062.1 - 2.9e-99 331.7 0.0 3.6e-99 331.4 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.6 EAQ86062.1 - 3.3e-05 23.8 0.0 5.8e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EAQ86062.1 - 0.0029 18.3 0.0 0.017 15.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EAQ86062.1 - 0.0029 18.2 0.0 0.024 15.2 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 EAQ86062.1 - 0.059 12.7 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family DUF1569 PF07606.11 EAQ86062.1 - 0.095 12.7 0.1 4.5 7.3 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1569) HsdM_N PF12161.8 EAQ86062.1 - 0.22 12.2 0.0 0.39 11.3 0.0 1.3 1 0 0 1 1 1 0 HsdM N-terminal domain PAC4 PF16093.5 EAQ86063.1 - 4.7e-11 42.7 0.0 6.4e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 Proteasome assembly chaperone 4 HEAT_EZ PF13513.6 EAQ86064.1 - 8.3e-29 99.6 11.4 3.8e-16 59.2 0.0 10.4 10 3 1 11 11 11 3 HEAT-like repeat HEAT PF02985.22 EAQ86064.1 - 1.1e-19 68.9 18.8 3.2e-06 26.9 0.0 10.2 12 0 0 12 12 11 3 HEAT repeat HEAT_2 PF13646.6 EAQ86064.1 - 6.6e-19 68.1 0.1 2.7e-06 27.6 0.0 7.3 5 3 2 7 7 7 3 HEAT repeats IBN_N PF03810.19 EAQ86064.1 - 4.1e-08 33.0 2.3 5.1e-06 26.3 0.3 4.8 3 1 0 3 3 3 1 Importin-beta N-terminal domain Vac14_Fab1_bd PF12755.7 EAQ86064.1 - 4.3e-08 33.6 0.1 0.51 11.0 0.0 6.3 5 2 1 7 7 7 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 EAQ86064.1 - 1.6e-07 31.5 0.3 0.17 11.9 0.0 4.6 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 MMS19_C PF12460.8 EAQ86064.1 - 1.6e-07 30.8 7.2 0.0086 15.2 0.0 5.2 3 2 1 5 5 5 2 RNAPII transcription regulator C-terminal CLASP_N PF12348.8 EAQ86064.1 - 0.00052 19.6 0.3 8.8 5.8 0.0 6.1 7 1 0 7 7 7 1 CLASP N terminal Arm PF00514.23 EAQ86064.1 - 0.00065 19.6 0.1 0.57 10.3 0.0 4.9 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat HEAT_PBS PF03130.16 EAQ86064.1 - 0.0047 17.5 1.3 3.4 8.6 0.0 4.9 4 0 0 4 4 2 1 PBS lyase HEAT-like repeat RTP1_C1 PF10363.9 EAQ86064.1 - 0.0096 16.1 0.0 0.33 11.1 0.0 3.1 3 0 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 DUF3437 PF11919.8 EAQ86064.1 - 0.013 15.4 0.1 2 8.4 0.0 4.1 5 0 0 5 5 4 0 Domain of unknown function (DUF3437) RIX1 PF08167.12 EAQ86064.1 - 0.043 13.6 0.1 22 4.8 0.0 4.8 6 2 2 8 8 8 0 rRNA processing/ribosome biogenesis TAF6_C PF07571.13 EAQ86064.1 - 0.055 13.8 0.0 15 6.0 0.0 4.5 5 1 0 5 5 5 0 TAF6 C-terminal HEAT repeat domain Importin_rep_4 PF18808.1 EAQ86064.1 - 0.14 12.4 2.4 4.3 7.7 0.2 3.5 3 0 0 3 3 3 0 Importin repeat Zn_clus PF00172.18 EAQ86067.1 - 8.2e-08 32.2 11.8 1.3e-07 31.6 11.8 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EAQ86067.1 - 4.5e-06 25.7 0.1 8.2e-06 24.9 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain SPRY PF00622.28 EAQ86068.1 - 5e-20 71.8 0.0 8.4e-20 71.1 0.0 1.4 1 0 0 1 1 1 1 SPRY domain EOS1 PF12326.8 EAQ86069.1 - 0.2 11.6 1.1 2 8.3 0.0 2.2 2 0 0 2 2 2 0 N-glycosylation protein Macoilin PF09726.9 EAQ86069.1 - 1 7.8 5.8 1.5 7.3 5.8 1.2 1 0 0 1 1 1 0 Macoilin family Exo_endo_phos PF03372.23 EAQ86071.1 - 6e-08 32.5 0.5 1.4e-07 31.3 0.5 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Sipho_Gp157 PF05565.11 EAQ86073.1 - 0.081 12.9 0.4 0.19 11.7 0.4 1.5 1 0 0 1 1 1 0 Siphovirus Gp157 SAP PF02037.27 EAQ86074.1 - 1.1e-12 47.4 0.0 1.7e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 SAP domain Tho1_MOS11_C PF18592.1 EAQ86074.1 - 0.00055 19.7 0.4 0.14 12.0 0.3 2.6 1 1 1 2 2 2 2 Tho1/MOS11 C-terminal domain HeH PF12949.7 EAQ86074.1 - 0.097 12.4 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 HeH/LEM domain Endomucin PF07010.12 EAQ86074.1 - 0.32 10.9 10.7 0.45 10.5 10.7 1.3 1 0 0 1 1 1 0 Endomucin DUF3439 PF11921.8 EAQ86074.1 - 1 9.3 5.6 2 8.4 5.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Mitofilin PF09731.9 EAQ86074.1 - 5 5.8 21.4 6.7 5.4 21.4 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Pinin_SDK_N PF04697.13 EAQ86075.1 - 0.082 13.6 0.2 0.091 13.4 0.2 1.0 1 0 0 1 1 1 0 pinin/SDK conserved region Methyltransf_11 PF08241.12 EAQ86076.1 - 0.0045 17.6 0.0 0.0098 16.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAQ86076.1 - 0.0069 17.1 0.0 0.014 16.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Aconitase PF00330.20 EAQ86077.1 - 3.4e-55 187.9 10.5 4e-21 75.5 0.4 4.9 1 1 3 4 4 4 4 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EAQ86077.1 - 1.1e-16 61.4 0.0 1.7e-16 60.7 0.0 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain Metallophos PF00149.28 EAQ86078.1 - 1.4e-17 64.9 0.2 2.5e-17 64.0 0.2 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TcdB_toxin_midN PF12256.8 EAQ86078.1 - 0.15 11.4 0.1 0.29 10.5 0.1 1.4 1 0 0 1 1 1 0 Insecticide toxin TcdB middle/N-terminal region FAD_binding_4 PF01565.23 EAQ86080.1 - 2.2e-22 79.3 5.2 2.4e-22 79.2 2.1 2.4 2 0 0 2 2 2 1 FAD binding domain GST_N_3 PF13417.6 EAQ86081.1 - 7.3e-14 51.9 0.0 1.2e-13 51.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EAQ86081.1 - 3.3e-13 49.8 0.0 6e-13 48.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EAQ86081.1 - 3.7e-11 43.1 0.0 7.8e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EAQ86081.1 - 1.4e-10 41.2 0.1 5.3e-10 39.4 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EAQ86081.1 - 1.9e-10 40.9 0.0 3.4e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EAQ86081.1 - 2.3e-06 27.5 0.1 7.6e-06 25.9 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain SF1-HH PF16275.5 EAQ86082.1 - 4.1e-44 149.5 1.4 8.1e-44 148.6 1.4 1.5 1 0 0 1 1 1 1 Splicing factor 1 helix-hairpin domain zf-CCHC PF00098.23 EAQ86082.1 - 7.4e-12 44.8 11.1 1.4e-05 24.9 0.8 2.4 2 0 0 2 2 2 2 Zinc knuckle KH_1 PF00013.29 EAQ86082.1 - 2.4e-08 33.7 0.1 4.6e-08 32.8 0.1 1.5 1 0 0 1 1 1 1 KH domain zf-CCHC_3 PF13917.6 EAQ86082.1 - 1.2e-06 28.3 6.8 0.00054 19.9 3.7 2.6 1 1 1 2 2 2 2 Zinc knuckle zf-CCHC_6 PF15288.6 EAQ86082.1 - 8e-05 22.4 6.6 0.033 14.0 0.3 2.8 1 1 1 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.6 EAQ86082.1 - 0.0012 18.5 4.9 0.45 10.3 0.4 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.6 EAQ86082.1 - 0.015 15.1 0.5 0.015 15.1 0.5 2.4 2 0 0 2 2 2 0 Zinc knuckle PHD_4 PF16866.5 EAQ86082.1 - 0.5 10.5 2.4 1.1 9.4 2.4 1.5 1 0 0 1 1 1 0 PHD-finger eIF3g PF12353.8 EAQ86082.1 - 3 8.2 7.4 3.8 7.9 0.5 2.9 2 1 1 3 3 3 0 Eukaryotic translation initiation factor 3 subunit G Peptidase_M28 PF04389.17 EAQ86083.1 - 1.9e-20 73.4 0.0 3.4e-20 72.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 CCDC106 PF15794.5 EAQ86083.1 - 0.063 13.0 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Med11 PF10280.9 EAQ86085.1 - 4.4e-43 147.0 0.5 7.9e-43 146.2 0.5 1.4 1 1 0 1 1 1 1 Mediator complex protein SUIM_assoc PF16619.5 EAQ86085.1 - 5.6 7.1 11.2 0.26 11.4 3.0 2.3 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 TFIID_NTD2 PF04494.15 EAQ86086.1 - 8.9e-42 142.4 0.0 1.3e-41 141.9 0.0 1.2 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain WD40 PF00400.32 EAQ86086.1 - 1.1e-39 133.6 22.0 1.6e-06 28.7 0.1 6.9 6 1 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAQ86086.1 - 1.7e-12 47.4 0.4 0.0066 16.7 0.0 5.5 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EAQ86086.1 - 1e-05 25.5 0.1 0.0015 18.4 0.0 3.2 2 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A LisH PF08513.11 EAQ86086.1 - 0.0017 18.3 0.0 0.0039 17.1 0.0 1.6 1 0 0 1 1 1 1 LisH Nup160 PF11715.8 EAQ86086.1 - 0.013 14.2 1.2 6.3 5.3 0.1 3.7 3 1 1 4 4 4 0 Nucleoporin Nup120/160 IKI3 PF04762.12 EAQ86086.1 - 0.25 9.3 0.1 0.47 8.4 0.1 1.4 1 1 0 1 1 1 0 IKI3 family Ge1_WD40 PF16529.5 EAQ86086.1 - 0.46 9.4 2.1 15 4.4 0.6 3.6 1 1 2 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Vps5 PF09325.10 EAQ86087.1 - 3.3e-87 291.9 4.1 6.1e-87 291.1 4.1 1.3 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 EAQ86087.1 - 1.1e-24 86.6 0.0 2.5e-24 85.4 0.0 1.6 1 0 0 1 1 1 1 PX domain BAR_3 PF16746.5 EAQ86087.1 - 0.0011 18.7 6.0 0.0036 17.0 2.3 2.5 1 1 1 2 2 2 1 BAR domain of APPL family BAR_2 PF10455.9 EAQ86087.1 - 0.0025 17.0 2.0 0.006 15.8 2.1 1.6 2 0 0 2 2 2 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR_3_WASP_bdg PF10456.9 EAQ86087.1 - 0.02 14.4 1.0 0.12 11.8 1.0 2.0 1 1 0 1 1 1 0 WASP-binding domain of Sorting nexin protein Lipase_GDSL PF00657.22 EAQ86087.1 - 0.034 14.1 0.0 0.081 12.9 0.0 1.6 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase DUF713 PF05218.14 EAQ86087.1 - 0.089 12.5 4.5 0.09 12.5 1.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF713) BAR PF03114.18 EAQ86087.1 - 0.15 11.7 9.3 0.46 10.1 9.3 1.8 1 1 0 1 1 1 0 BAR domain PilJ PF13675.6 EAQ86087.1 - 6.5 6.8 8.4 0.53 10.3 0.3 3.0 3 1 1 4 4 4 0 Type IV pili methyl-accepting chemotaxis transducer N-term Ribosomal_L31 PF01197.18 EAQ86088.1 - 0.00018 21.6 0.0 0.0004 20.5 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L31 Flavin_Reduct PF01613.18 EAQ86089.1 - 1.9e-34 119.0 0.0 2.8e-34 118.4 0.0 1.2 1 0 0 1 1 1 1 Flavin reductase like domain FKBP_C PF00254.28 EAQ86090.1 - 1.5e-34 118.2 0.0 1.7e-34 118.0 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase HSP90 PF00183.18 EAQ86092.1 - 2e-109 366.9 4.5 2.4e-109 366.6 4.5 1.0 1 0 0 1 1 1 1 Hsp90 protein LOH1CR12 PF10158.9 EAQ86092.1 - 0.024 14.7 0.3 0.04 13.9 0.3 1.4 1 0 0 1 1 1 0 Tumour suppressor protein MBOAT PF03062.19 EAQ86094.1 - 1.3e-33 116.8 10.6 1.5e-32 113.3 9.9 2.1 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family DnaJ PF00226.31 EAQ86095.1 - 2.4e-10 40.4 0.1 4.7e-10 39.5 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain Metallophos PF00149.28 EAQ86097.1 - 6.6e-17 62.7 0.0 1.2e-16 61.9 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EAQ86097.1 - 2.7e-07 30.9 0.5 9.7e-06 25.9 0.5 2.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Paralemmin PF03285.15 EAQ86098.1 - 1.3 8.5 5.2 4.2 6.9 5.2 2.0 1 1 0 1 1 1 0 Paralemmin LigA PF07746.11 EAQ86100.1 - 0.18 12.0 0.0 0.25 11.5 0.0 1.2 1 0 0 1 1 1 0 Aromatic-ring-opening dioxygenase LigAB, LigA subunit IMUP PF15761.5 EAQ86100.1 - 0.21 12.3 6.7 0.27 11.9 6.7 1.3 1 0 0 1 1 1 0 Immortalisation up-regulated protein DNA_primase_lrg PF04104.14 EAQ86101.1 - 2.6e-74 250.0 0.0 3.9e-74 249.4 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit CLP_protease PF00574.23 EAQ86103.1 - 1.2e-52 178.4 0.7 1.5e-52 178.1 0.7 1.1 1 0 0 1 1 1 1 Clp protease SpoOE-like PF09388.10 EAQ86103.1 - 0.044 13.7 0.3 0.044 13.7 0.3 1.8 2 0 0 2 2 2 0 Spo0E like sporulation regulatory protein ILVD_EDD PF00920.21 EAQ86104.1 - 4.3e-214 711.9 0.0 5e-214 711.7 0.0 1.0 1 0 0 1 1 1 1 Dehydratase family Kinesin PF00225.23 EAQ86106.1 - 4e-104 348.1 0.1 4e-104 348.1 0.1 1.7 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EAQ86106.1 - 5.9e-54 182.1 0.0 1.5e-53 180.8 0.0 1.8 1 0 0 1 1 1 1 Microtubule binding WEMBL PF05701.11 EAQ86106.1 - 3.5e-06 26.0 15.3 3.5e-06 26.0 15.3 2.7 2 1 1 3 3 3 2 Weak chloroplast movement under blue light AAA_16 PF13191.6 EAQ86106.1 - 0.0081 16.5 2.4 0.1 13.0 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.6 EAQ86106.1 - 0.013 15.3 0.7 0.042 13.6 0.0 2.2 2 1 0 2 2 2 0 AAA domain DUF3367 PF11847.8 EAQ86106.1 - 0.44 8.3 2.5 0.25 9.2 0.1 1.6 2 0 0 2 2 2 0 Alpha-(1->3)-arabinofuranosyltransferase DUF3584 PF12128.8 EAQ86106.1 - 3.6 5.0 44.6 0.031 11.8 35.9 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) FAD_binding_3 PF01494.19 EAQ86107.1 - 4.6e-15 55.7 0.0 3.5e-14 52.8 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain Thioesterase PF00975.20 EAQ86108.1 - 5.4e-13 49.6 0.3 7.4e-13 49.2 0.3 1.2 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.7 EAQ86108.1 - 2.8e-08 34.6 4.2 3.9e-08 34.2 4.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 EAQ86108.1 - 0.057 13.3 0.0 0.082 12.7 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF2974 PF11187.8 EAQ86108.1 - 0.076 12.6 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Cerato-platanin PF07249.12 EAQ86110.1 - 8.2e-47 158.2 1.5 1.5e-46 157.3 1.5 1.4 1 0 0 1 1 1 1 Cerato-platanin DUF2835 PF11197.8 EAQ86110.1 - 0.038 13.8 0.1 0.34 10.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2835) Zn_clus PF00172.18 EAQ86111.1 - 5.3e-10 39.2 9.8 9.2e-10 38.5 9.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EAQ86111.1 - 9.9e-07 28.0 3.2 6.9e-06 25.3 3.2 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain Exo_endo_phos PF03372.23 EAQ86113.1 - 2.2e-15 56.8 0.1 2.9e-15 56.4 0.1 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_8 PF13855.6 EAQ86114.1 - 3.3e-06 26.8 0.1 4.4e-06 26.3 0.1 1.2 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 EAQ86114.1 - 0.00012 22.3 0.2 0.00024 21.4 0.2 1.4 1 0 0 1 1 1 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EAQ86114.1 - 0.0081 16.6 0.9 10 7.1 0.4 3.2 3 0 0 3 3 3 2 Leucine Rich Repeat Methyltransf_25 PF13649.6 EAQ86116.1 - 5.2e-15 55.9 0.0 1.1e-14 54.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EAQ86116.1 - 2.5e-10 40.9 0.0 1e-09 38.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAQ86116.1 - 6.6e-08 32.5 0.0 1.1e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EAQ86116.1 - 1e-06 28.7 0.0 1.8e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EAQ86116.1 - 6.4e-06 26.8 0.0 1.3e-05 25.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EAQ86116.1 - 1.5e-05 24.5 0.0 2.5e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Complex1_LYR PF05347.15 EAQ86117.1 - 0.0027 17.7 0.0 0.0061 16.6 0.0 1.6 1 0 0 1 1 1 1 Complex 1 protein (LYR family) 4HBT_2 PF13279.6 EAQ86118.1 - 4.7e-14 52.9 0.1 1.1e-13 51.7 0.1 1.6 1 1 0 1 1 1 1 Thioesterase-like superfamily DEC-1_N PF04625.13 EAQ86118.1 - 0.12 11.4 5.8 0.16 10.9 5.8 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region TBCA PF02970.16 EAQ86119.1 - 0.0013 19.0 4.1 0.0013 19.0 4.1 2.7 1 1 1 2 2 2 1 Tubulin binding cofactor A DUF4407 PF14362.6 EAQ86119.1 - 5.3 6.3 37.4 71 2.6 13.9 3.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) CFEM PF05730.11 EAQ86120.1 - 1.2e-12 47.7 8.6 1.7e-12 47.2 8.6 1.3 1 0 0 1 1 1 1 CFEM domain NOA36 PF06524.12 EAQ86120.1 - 0.004 16.5 2.8 0.006 16.0 2.8 1.2 1 0 0 1 1 1 1 NOA36 protein NAD_kinase PF01513.21 EAQ86121.1 - 2.8e-49 167.9 0.0 4.6e-48 163.9 0.0 2.0 1 1 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 EAQ86121.1 - 0.03 13.9 0.0 0.056 13.1 0.0 1.4 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain Acyltransferase PF01553.21 EAQ86122.1 - 6.6e-26 90.5 0.0 9.3e-26 90.1 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 EAQ86122.1 - 1.5e-13 50.6 0.1 2.7e-13 49.8 0.1 1.4 1 0 0 1 1 1 1 Acyltransferase C-terminus TauD PF02668.16 EAQ86124.1 - 9.1e-29 101.1 0.0 1.5e-28 100.3 0.0 1.4 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 EAQ86124.1 - 0.044 12.9 0.0 0.067 12.3 0.0 1.2 1 0 0 1 1 1 0 CsiD Sua5_yciO_yrdC PF01300.18 EAQ86125.1 - 2e-13 50.3 0.0 2.5e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 Telomere recombination RVT_1 PF00078.27 EAQ86126.1 - 6.8e-23 81.3 0.0 8.8e-16 58.1 0.0 2.2 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RecC_C PF17946.1 EAQ86126.1 - 0.0037 17.1 3.0 0.35 10.6 0.2 2.8 2 0 0 2 2 2 2 RecC C-terminal domain PriC PF07445.12 EAQ86126.1 - 0.23 11.4 3.2 0.14 12.0 1.1 1.7 2 0 0 2 2 2 0 Primosomal replication protein priC Zn_clus PF00172.18 EAQ86127.1 - 0.16 12.2 5.7 0.33 11.1 5.7 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_2 PF07719.17 EAQ86128.1 - 1.4e-09 37.3 8.1 0.00063 19.7 0.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 EAQ86128.1 - 2.5e-06 27.0 3.1 0.092 12.6 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 EAQ86128.1 - 4.2e-05 24.1 12.6 0.04 14.6 0.6 3.4 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 EAQ86128.1 - 0.00027 21.2 5.9 0.0032 17.7 0.8 2.6 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 EAQ86128.1 - 0.00069 19.6 0.5 0.074 13.3 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 EAQ86128.1 - 0.015 15.7 1.2 0.1 13.1 0.0 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 EAQ86128.1 - 0.11 13.4 0.4 0.11 13.4 0.4 3.5 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 EAQ86128.1 - 0.12 13.0 5.5 0.3 11.8 1.4 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.6 EAQ86128.1 - 0.17 12.0 6.2 4.2 7.6 1.0 3.0 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 EAQ86128.1 - 5.2 7.9 5.8 4.4 8.2 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 EAQ86128.1 - 5.6 7.0 11.6 15 5.6 0.2 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF89 PF01937.19 EAQ86132.1 - 1.2e-123 412.6 0.0 1.4e-123 412.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 Lipase_3 PF01764.25 EAQ86133.1 - 9.7e-21 74.1 0.0 3e-20 72.5 0.0 1.8 2 0 0 2 2 2 1 Lipase (class 3) RAI16-like PF10257.9 EAQ86134.1 - 9.8e-69 231.9 2.5 1.4e-68 231.4 2.5 1.2 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein Glyco_hydro_10 PF00331.20 EAQ86135.1 - 9.5e-54 182.7 0.0 1.3e-53 182.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 DUF2457 PF10446.9 EAQ86135.1 - 0.35 10.0 0.7 0.46 9.6 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) FAD_binding_4 PF01565.23 EAQ86136.1 - 1.1e-26 93.3 5.9 1.1e-26 93.3 5.9 1.6 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 EAQ86136.1 - 6.4e-12 45.4 0.2 1.1e-11 44.6 0.2 1.4 1 0 0 1 1 1 1 Berberine and berberine like Cutinase PF01083.22 EAQ86137.1 - 9.2e-50 169.1 0.4 1.1e-49 168.8 0.5 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 EAQ86137.1 - 0.0003 20.4 0.0 0.00042 20.0 0.0 1.3 1 0 0 1 1 1 1 PE-PPE domain VirJ PF06057.11 EAQ86137.1 - 0.00067 19.6 0.0 0.0011 18.9 0.0 1.2 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) Abhydrolase_1 PF00561.20 EAQ86137.1 - 0.076 12.6 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold p450 PF00067.22 EAQ86140.1 - 4.4e-45 154.3 0.0 5.6e-45 154.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_43 PF04616.14 EAQ86141.1 - 2.7e-65 220.6 4.5 3.4e-65 220.2 4.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 EAQ86141.1 - 2.2e-23 83.0 0.0 3.6e-23 82.3 0.0 1.3 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain Glyco_hydro_32N PF00251.20 EAQ86141.1 - 0.12 12.0 0.3 0.41 10.2 0.1 1.9 2 0 0 2 2 2 0 Glycosyl hydrolases family 32 N-terminal domain GFA PF04828.14 EAQ86142.1 - 1.5e-09 38.1 0.0 1e-06 29.0 0.0 2.6 1 1 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Ytp1 PF10355.9 EAQ86143.1 - 5e-68 229.3 22.0 5e-68 229.3 22.0 2.3 1 1 1 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 EAQ86143.1 - 2.5e-34 117.2 1.8 2.5e-34 117.2 1.8 2.8 4 0 0 4 4 4 1 Domain of unknown function (DUF2427) Cytochrom_B561 PF03188.16 EAQ86143.1 - 0.019 15.1 5.2 0.019 15.1 5.2 3.6 4 1 1 5 5 5 0 Eukaryotic cytochrome b561 Peptidase_M20 PF01546.28 EAQ86144.1 - 4.6e-08 33.0 0.2 6.5e-08 32.5 0.2 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EAQ86144.1 - 1.1e-05 25.3 0.0 3.8e-05 23.6 0.0 1.9 1 1 0 1 1 1 1 Peptidase dimerisation domain Promethin PF16015.5 EAQ86145.1 - 2.7e-22 78.7 13.5 3.5e-22 78.3 13.5 1.1 1 0 0 1 1 1 1 Promethin Ctr PF04145.15 EAQ86145.1 - 0.039 14.6 0.2 0.16 12.6 0.5 1.7 2 0 0 2 2 2 0 Ctr copper transporter family GFO_IDH_MocA PF01408.22 EAQ86147.1 - 4.1e-23 82.5 0.0 6.8e-23 81.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EAQ86147.1 - 1.2e-09 38.1 0.0 2.3e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 EAQ86147.1 - 0.00089 19.9 0.0 0.0023 18.6 0.0 1.6 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain FAD_binding_4 PF01565.23 EAQ86148.1 - 8.8e-24 83.8 1.5 1.6e-23 83.0 1.5 1.4 1 0 0 1 1 1 1 FAD binding domain adh_short PF00106.25 EAQ86149.1 - 3.8e-27 95.0 0.3 5.1e-27 94.6 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EAQ86149.1 - 8.7e-20 71.3 0.2 1.5e-19 70.5 0.2 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EAQ86149.1 - 5.3e-15 55.8 1.0 1.1e-14 54.8 1.0 1.5 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EAQ86149.1 - 9.1e-08 31.6 0.0 1.1e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 EAQ86149.1 - 2.2e-07 30.6 0.4 8e-07 28.8 0.4 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EAQ86149.1 - 2.4e-05 23.9 0.2 3.1e-05 23.5 0.2 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 2-Hacid_dh_C PF02826.19 EAQ86149.1 - 0.065 12.6 0.7 6.8 6.0 0.0 2.3 1 1 1 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 EAQ86149.1 - 0.94 9.3 4.7 2.9 7.7 4.7 1.9 1 1 0 1 1 1 0 NAD(P)H-binding PAF-AH_p_II PF03403.13 EAQ86150.1 - 9.1e-07 27.7 0.0 0.00019 20.1 0.0 2.1 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II LytR_C PF13399.6 EAQ86150.1 - 0.069 14.1 0.0 0.14 13.2 0.0 1.5 1 0 0 1 1 1 0 LytR cell envelope-related transcriptional attenuator PGM_PMM_I PF02878.16 EAQ86150.1 - 0.15 11.7 0.0 0.32 10.7 0.0 1.4 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I Abhydrolase_5 PF12695.7 EAQ86150.1 - 0.16 11.7 0.3 0.28 10.9 0.0 1.5 2 0 0 2 2 2 0 Alpha/beta hydrolase family zf-RVT PF13966.6 EAQ86151.1 - 0.082 13.6 0.0 0.33 11.7 0.0 2.0 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase Abhydrolase_6 PF12697.7 EAQ86152.1 - 1.1e-06 29.5 0.3 2.1e-06 28.5 0.3 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.14 EAQ86152.1 - 1.7e-05 24.4 0.0 2.7e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 EAQ86152.1 - 0.042 13.1 0.0 0.077 12.2 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 LIDHydrolase PF10230.9 EAQ86152.1 - 0.16 11.5 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase DUF1664 PF07889.12 EAQ86153.1 - 0.008 16.2 16.7 0.086 12.9 0.6 3.0 1 1 1 3 3 3 2 Protein of unknown function (DUF1664) GAS PF13851.6 EAQ86153.1 - 0.034 13.5 18.8 0.027 13.8 14.0 2.3 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding CENP-H PF05837.12 EAQ86153.1 - 0.068 13.6 15.7 0.068 13.6 11.4 2.2 2 0 0 2 2 2 0 Centromere protein H (CENP-H) C12orf66_like PF09404.10 EAQ86153.1 - 0.11 11.3 2.0 0.14 11.0 2.0 1.1 1 0 0 1 1 1 0 KICSTOR complex C12orf66 like DUF3567 PF12091.8 EAQ86153.1 - 0.19 11.9 2.8 0.32 11.1 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3567) TPR_MLP1_2 PF07926.12 EAQ86153.1 - 0.25 11.4 20.8 0.36 10.9 14.5 2.4 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF4407 PF14362.6 EAQ86153.1 - 0.29 10.5 15.9 0.33 10.3 15.4 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) THOC7 PF05615.13 EAQ86153.1 - 0.29 11.4 0.1 0.29 11.4 0.1 2.5 2 1 0 2 2 2 0 Tho complex subunit 7 OmpH PF03938.14 EAQ86153.1 - 0.45 10.9 17.2 2.7 8.3 12.1 2.4 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF4778 PF16008.5 EAQ86153.1 - 0.49 10.4 6.4 0.73 9.8 6.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) Lebercilin PF15619.6 EAQ86153.1 - 0.78 9.4 24.4 0.15 11.7 5.3 2.9 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DivIVA PF05103.13 EAQ86153.1 - 2.6 8.2 23.1 3.5 7.7 2.3 2.6 2 1 0 2 2 2 0 DivIVA protein Tho2 PF11262.8 EAQ86153.1 - 2.8 7.1 11.6 0.29 10.3 6.8 1.7 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 ZapB PF06005.12 EAQ86153.1 - 3 8.4 20.4 2.1 8.8 12.4 3.2 2 1 1 3 3 3 0 Cell division protein ZapB DivIC PF04977.15 EAQ86153.1 - 4.1 7.3 17.5 0.65 9.8 7.0 2.9 2 1 1 3 3 3 0 Septum formation initiator Atg14 PF10186.9 EAQ86153.1 - 7.3 5.6 14.1 11 5.1 14.1 1.4 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TMPIT PF07851.13 EAQ86153.1 - 7.9 5.6 10.9 5.9 6.0 8.5 1.8 2 0 0 2 2 2 0 TMPIT-like protein NACHT PF05729.12 EAQ86154.1 - 3.9e-05 23.6 0.0 0.00028 20.8 0.0 2.3 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EAQ86154.1 - 7.1e-05 23.3 0.0 0.00017 22.0 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.22 EAQ86154.1 - 0.0021 18.4 0.0 0.0095 16.3 0.0 2.0 2 0 0 2 2 2 1 RNA helicase KAP_NTPase PF07693.14 EAQ86154.1 - 0.0096 15.2 0.1 0.063 12.5 0.0 2.0 1 1 1 2 2 2 1 KAP family P-loop domain Noc2 PF03715.13 EAQ86154.1 - 0.091 12.0 0.1 0.14 11.4 0.1 1.2 1 0 0 1 1 1 0 Noc2p family Glyco_hydro_72 PF03198.14 EAQ86156.1 - 1.8e-120 402.0 2.3 2.6e-120 401.4 2.3 1.2 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 EAQ86156.1 - 1.6e-23 83.2 4.7 4.2e-23 81.8 4.7 1.8 1 0 0 1 1 1 1 X8 domain Glyco_hydro_2_C PF02836.17 EAQ86156.1 - 0.00023 20.4 0.5 0.001 18.3 0.5 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Lipoxygenase PF00305.19 EAQ86157.1 - 1.7e-47 162.3 4.4 8.7e-46 156.6 3.2 2.0 2 0 0 2 2 2 2 Lipoxygenase Arylesterase PF01731.20 EAQ86158.1 - 0.072 13.3 0.0 1 9.6 0.0 2.6 2 1 0 2 2 2 0 Arylesterase Oxidored_FMN PF00724.20 EAQ86159.1 - 3.1e-09 36.5 0.0 0.001 18.4 0.0 2.2 2 0 0 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family Cellulase-like PF12876.7 EAQ86159.1 - 0.21 10.9 0.0 0.25 10.7 0.0 1.1 1 0 0 1 1 1 0 Sugar-binding cellulase-like Hint_2 PF13403.6 EAQ86160.1 - 0.00041 20.7 0.0 0.00087 19.6 0.0 1.6 1 0 0 1 1 1 1 Hint domain Pilin_N PF07790.11 EAQ86160.1 - 0.021 15.7 0.1 0.021 15.7 0.1 2.5 2 0 0 2 2 2 0 Archaeal Type IV pilin, N-terminal DUF2914 PF11141.8 EAQ86160.1 - 0.059 13.1 0.0 0.19 11.5 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2914) DBINO PF13892.6 EAQ86161.1 - 9.8e-49 165.2 16.4 9.8e-49 165.2 16.4 5.4 3 2 0 5 5 5 1 DNA-binding domain SNF2_N PF00176.23 EAQ86161.1 - 5.3e-31 107.6 0.9 1.2e-16 60.4 0.0 2.5 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 EAQ86161.1 - 8.5e-20 71.2 0.0 2.1e-19 69.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EAQ86161.1 - 0.00033 20.7 0.0 0.0016 18.4 0.0 2.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 EAQ86161.1 - 0.0035 16.6 0.0 0.078 12.1 0.0 2.9 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 Fe_hyd_lg_C PF02906.14 EAQ86161.1 - 0.051 13.2 3.5 0.14 11.8 1.7 2.3 2 0 0 2 2 2 0 Iron only hydrogenase large subunit, C-terminal domain baeRF_family12 PF18856.1 EAQ86161.1 - 0.099 13.2 0.1 0.099 13.2 0.1 6.4 5 2 3 8 8 8 0 Bacterial archaeo-eukaryotic release factor family 12 ABC_tran PF00005.27 EAQ86162.1 - 3e-34 118.5 0.0 2.1e-20 73.6 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_tran_Xtn PF12848.7 EAQ86162.1 - 2.2e-22 78.9 2.0 2.2e-22 78.9 2.0 3.1 4 0 0 4 4 3 1 ABC transporter AAA_21 PF13304.6 EAQ86162.1 - 3.9e-12 46.6 0.0 0.0017 18.2 0.0 3.6 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EAQ86162.1 - 1e-08 34.8 0.1 0.0031 17.2 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 EAQ86162.1 - 1.7e-08 35.2 2.2 0.019 15.4 0.0 3.5 3 1 0 3 3 3 2 AAA domain AAA_16 PF13191.6 EAQ86162.1 - 5.2e-07 30.2 0.0 0.0044 17.4 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_15 PF13175.6 EAQ86162.1 - 1.7e-06 28.0 0.3 0.03 14.1 0.0 2.7 3 0 0 3 3 3 2 AAA ATPase domain SMC_N PF02463.19 EAQ86162.1 - 3.1e-06 26.8 0.0 0.35 10.3 0.0 3.7 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EAQ86162.1 - 3.1e-06 27.2 0.4 0.0096 15.8 0.0 2.7 3 0 0 3 3 2 2 RsgA GTPase AAA_28 PF13521.6 EAQ86162.1 - 4.5e-06 27.0 0.0 0.002 18.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EAQ86162.1 - 4.5e-06 27.0 0.0 0.048 13.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 EAQ86162.1 - 6.2e-06 26.8 0.0 0.069 13.7 0.0 3.0 3 0 0 3 3 2 2 AAA domain MMR_HSR1 PF01926.23 EAQ86162.1 - 6.4e-06 26.2 0.1 0.024 14.7 0.3 3.0 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA PF00004.29 EAQ86162.1 - 0.00013 22.4 0.0 0.48 10.8 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 EAQ86162.1 - 0.00014 22.0 0.2 0.46 10.6 0.0 3.4 3 0 0 3 3 3 1 AAA domain NACHT PF05729.12 EAQ86162.1 - 0.00014 21.8 0.6 0.2 11.6 0.0 2.7 2 0 0 2 2 2 2 NACHT domain AAA_5 PF07728.14 EAQ86162.1 - 0.00016 21.7 0.2 0.61 10.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 EAQ86162.1 - 0.0002 21.7 1.9 1.7 9.0 0.0 3.4 3 0 0 3 3 3 2 RNA helicase AAA_14 PF13173.6 EAQ86162.1 - 0.0011 19.0 0.0 2.1 8.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_27 PF13514.6 EAQ86162.1 - 0.0013 18.4 0.1 0.43 10.1 0.0 3.0 3 0 0 3 3 2 1 AAA domain NB-ARC PF00931.22 EAQ86162.1 - 0.0019 17.4 0.1 4.4 6.4 0.0 3.4 3 1 1 4 4 4 1 NB-ARC domain AAA_24 PF13479.6 EAQ86162.1 - 0.0031 17.3 0.6 2 8.1 0.0 3.2 3 0 0 3 3 3 1 AAA domain DUF2813 PF11398.8 EAQ86162.1 - 0.0034 16.7 0.0 0.77 8.9 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2813) AAA_25 PF13481.6 EAQ86162.1 - 0.004 16.8 0.0 0.42 10.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain Roc PF08477.13 EAQ86162.1 - 0.0041 17.3 0.1 3.6 7.8 0.1 2.9 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 EAQ86162.1 - 0.0085 16.2 0.9 6.7 6.7 0.0 3.6 3 1 0 4 4 4 0 Dynamin family AAA_17 PF13207.6 EAQ86162.1 - 0.0087 16.5 0.0 2.1 8.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 EAQ86162.1 - 0.02 14.8 0.0 1.4 8.8 0.0 2.5 2 0 0 2 2 2 0 NTPase AAA_30 PF13604.6 EAQ86162.1 - 0.026 14.3 1.5 3.4 7.3 0.1 3.4 4 0 0 4 4 4 0 AAA domain ATPase_2 PF01637.18 EAQ86162.1 - 0.027 14.4 0.1 3.9 7.3 0.0 2.7 3 0 0 3 3 2 0 ATPase domain predominantly from Archaea AAA_7 PF12775.7 EAQ86162.1 - 0.038 13.5 0.0 2.3 7.7 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF815 PF05673.13 EAQ86162.1 - 0.044 13.0 0.2 2.4 7.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) DUF87 PF01935.17 EAQ86162.1 - 0.051 13.7 0.1 14 5.7 0.0 2.7 2 0 0 2 2 2 0 Helicase HerA, central domain FeoB_N PF02421.18 EAQ86162.1 - 0.058 12.9 0.1 8.8 5.8 0.0 2.9 3 0 0 3 3 3 0 Ferrous iron transport protein B MCM PF00493.23 EAQ86162.1 - 0.077 12.1 0.1 8.4 5.4 0.0 2.3 2 0 0 2 2 2 0 MCM P-loop domain DAP3 PF10236.9 EAQ86162.1 - 0.087 12.0 0.1 6.7 5.8 0.0 2.6 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 TsaE PF02367.17 EAQ86162.1 - 0.12 12.4 0.4 28 4.7 0.0 3.0 2 1 1 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF3584 PF12128.8 EAQ86162.1 - 0.18 9.3 1.2 0.41 8.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) CPP1-like PF11833.8 EAQ86163.1 - 0.0027 17.4 4.0 0.072 12.7 0.0 2.2 2 0 0 2 2 2 2 Protein CHAPERONE-LIKE PROTEIN OF POR1-like S1FA PF04689.13 EAQ86163.1 - 0.07 13.3 0.6 0.27 11.4 0.1 2.1 2 0 0 2 2 2 0 DNA binding protein S1FA LIDHydrolase PF10230.9 EAQ86164.1 - 4.6e-55 187.0 0.0 5.5e-55 186.8 0.0 1.1 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase PGAP1 PF07819.13 EAQ86164.1 - 0.00052 19.8 0.1 0.0008 19.2 0.1 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 EAQ86164.1 - 0.00055 20.6 7.1 0.0011 19.6 7.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 EAQ86164.1 - 0.0074 16.1 0.0 0.011 15.5 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 EAQ86164.1 - 0.032 13.5 0.1 0.057 12.7 0.1 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 CVNH PF08881.10 EAQ86165.1 - 1.8e-09 38.2 0.1 2.2e-09 37.9 0.1 1.2 1 0 0 1 1 1 1 CVNH domain EGF_3 PF12947.7 EAQ86165.1 - 0.27 11.5 5.1 11 6.4 0.8 2.7 2 1 0 2 2 2 0 EGF domain Spherulin4 PF12138.8 EAQ86166.1 - 7.8e-40 137.0 0.0 1e-39 136.7 0.0 1.1 1 0 0 1 1 1 1 Spherulation-specific family 4 Sod_Fe_C PF02777.18 EAQ86168.1 - 1.2e-35 121.7 0.4 2.1e-35 120.9 0.1 1.5 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 EAQ86168.1 - 1.4e-33 115.2 2.2 1.4e-33 115.2 2.2 2.1 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain T5orf172 PF10544.9 EAQ86169.1 - 7.1e-26 90.8 0.2 2e-25 89.3 0.2 1.8 1 0 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 EAQ86169.1 - 5.6e-24 84.6 1.9 6.8e-24 84.3 0.2 2.1 3 0 0 3 3 3 1 Meiotically up-regulated gene 113 Ribosomal_60s PF00428.19 EAQ86171.1 - 6.3 7.5 12.8 0.56 10.8 8.0 1.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein p450 PF00067.22 EAQ86172.1 - 2.3e-13 49.7 0.0 1e-05 24.5 0.0 2.6 2 1 0 2 2 2 2 Cytochrome P450 Radical_SAM_C PF16199.5 EAQ86175.1 - 5e-32 109.8 0.0 1e-31 108.8 0.0 1.5 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 EAQ86175.1 - 1.4e-16 61.3 0.1 4.4e-16 59.7 0.0 1.8 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 EAQ86175.1 - 4.4e-09 36.6 0.1 1.1e-08 35.3 0.1 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EAQ86175.1 - 1.1e-05 25.4 0.0 2.1e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EAQ86175.1 - 0.028 14.9 0.0 0.068 13.6 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain CoA_binding PF02629.19 EAQ86176.1 - 4e-27 94.7 3.9 6.5e-27 94.1 0.9 2.2 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 EAQ86176.1 - 8.5e-24 84.1 0.1 1.6e-23 83.2 0.1 1.5 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 EAQ86176.1 - 2.6e-09 37.0 0.0 4.4e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 EAQ86176.1 - 0.00011 22.6 0.2 0.0004 20.8 0.0 2.0 2 0 0 2 2 2 1 CoA binding domain UQ_con PF00179.26 EAQ86177.1 - 5.4e-28 97.4 0.3 2.3e-20 72.7 0.1 2.1 2 0 0 2 2 2 2 Ubiquitin-conjugating enzyme UBA_3 PF09288.10 EAQ86177.1 - 0.076 12.8 0.1 0.16 11.8 0.1 1.5 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain UEV PF05743.13 EAQ86177.1 - 0.095 12.6 0.3 0.16 11.9 0.3 1.3 1 0 0 1 1 1 0 UEV domain AAA PF00004.29 EAQ86178.1 - 3.5e-25 88.9 0.2 2.1e-13 50.9 0.0 2.4 1 1 1 2 2 2 2 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 EAQ86178.1 - 4.5e-12 45.7 1.1 1.4e-11 44.2 0.2 2.1 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 EAQ86178.1 - 7.8e-11 41.6 0.9 1.4e-10 40.8 0.9 1.4 1 0 0 1 1 1 1 AAA+ lid domain DUF815 PF05673.13 EAQ86178.1 - 0.0003 20.0 0.0 0.00058 19.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_28 PF13521.6 EAQ86178.1 - 0.00051 20.3 0.1 0.0018 18.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EAQ86178.1 - 0.0012 19.2 0.0 0.0033 17.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain Prot_ATP_OB_N PF17758.1 EAQ86178.1 - 0.0015 18.1 0.8 0.009 15.6 0.0 2.4 2 0 0 2 2 2 1 Proteasomal ATPase OB N-terminal domain AAA_33 PF13671.6 EAQ86178.1 - 0.0015 18.7 0.1 0.02 15.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EAQ86178.1 - 0.0015 18.9 0.0 0.0032 17.9 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 EAQ86178.1 - 0.0041 17.1 0.2 0.013 15.5 0.1 1.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EAQ86178.1 - 0.0088 15.8 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain PhoH PF02562.16 EAQ86178.1 - 0.013 15.0 1.2 0.051 13.0 1.2 1.8 1 1 0 1 1 1 0 PhoH-like protein IstB_IS21 PF01695.17 EAQ86178.1 - 0.016 14.9 0.0 0.033 13.9 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.13 EAQ86178.1 - 0.018 14.3 0.1 0.052 12.8 0.0 1.7 2 0 0 2 2 2 0 TIP49 P-loop domain AAA_3 PF07726.11 EAQ86178.1 - 0.018 14.9 0.0 0.037 13.9 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 EAQ86178.1 - 0.018 15.6 0.0 0.041 14.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 EAQ86178.1 - 0.054 12.9 0.1 0.1 12.0 0.1 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 EAQ86178.1 - 0.061 13.7 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Zeta_toxin PF06414.12 EAQ86178.1 - 0.07 12.4 0.1 0.16 11.2 0.1 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_25 PF13481.6 EAQ86178.1 - 0.13 11.8 0.1 0.41 10.2 0.1 1.8 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EAQ86178.1 - 0.16 11.6 0.7 0.35 10.6 0.1 1.8 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 EAQ86178.1 - 0.19 10.9 0.1 0.28 10.4 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.27 EAQ86178.1 - 0.21 12.1 0.7 0.7 10.4 0.2 2.3 2 1 0 2 2 1 0 ABC transporter Dimer_Tnp_hAT PF05699.14 EAQ86179.1 - 3.3e-13 49.2 0.1 7.4e-13 48.1 0.1 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Ribosomal_L13 PF00572.18 EAQ86180.1 - 1.5e-11 44.6 0.0 1.5e-09 38.2 0.0 2.3 1 1 0 1 1 1 1 Ribosomal protein L13 DSBA PF01323.20 EAQ86180.1 - 0.057 13.2 0.0 0.078 12.8 0.0 1.2 1 0 0 1 1 1 0 DSBA-like thioredoxin domain BAG PF02179.16 EAQ86181.1 - 3.4e-17 62.6 0.0 6.1e-17 61.8 0.0 1.4 1 0 0 1 1 1 1 BAG domain ubiquitin PF00240.23 EAQ86181.1 - 7.8e-05 22.3 0.0 0.00015 21.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_4 PF18036.1 EAQ86181.1 - 0.015 15.3 0.0 0.032 14.3 0.0 1.6 1 1 0 1 1 1 0 Ubiquitin-like domain Ubiquitin_5 PF18037.1 EAQ86181.1 - 0.034 14.5 0.1 0.11 12.9 0.0 1.8 2 0 0 2 2 2 0 Ubiquitin-like domain Glutaredoxin PF00462.24 EAQ86182.1 - 1.7e-20 73.0 0.0 2.6e-20 72.4 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.6 EAQ86182.1 - 1e-05 25.8 0.0 1.3e-05 25.5 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DUF836 PF05768.14 EAQ86182.1 - 0.0086 16.5 0.0 0.011 16.1 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) GST_N_2 PF13409.6 EAQ86182.1 - 0.013 15.8 0.0 0.017 15.4 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Thioredoxin_2 PF13098.6 EAQ86182.1 - 0.018 15.5 0.2 0.041 14.3 0.2 1.6 1 1 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_3 PF13192.6 EAQ86182.1 - 0.023 14.7 0.0 0.031 14.3 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin domain Thioredoxin PF00085.20 EAQ86182.1 - 0.031 14.3 0.0 0.035 14.1 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_4 PF13462.6 EAQ86182.1 - 0.058 13.5 0.9 2.9 8.0 0.4 2.1 1 1 1 2 2 2 0 Thioredoxin DSBA PF01323.20 EAQ86182.1 - 0.33 10.7 1.9 1 9.1 0.5 2.0 1 1 1 2 2 2 0 DSBA-like thioredoxin domain Chalcone_2 PF16035.5 EAQ86183.1 - 1.7e-48 165.1 0.1 1.7e-31 109.6 0.0 2.2 1 1 1 2 2 2 2 Chalcone isomerase like Chalcone_3 PF16036.5 EAQ86183.1 - 0.021 14.9 0.0 0.035 14.2 0.0 1.4 1 1 0 1 1 1 0 Chalcone isomerase-like LRR_6 PF13516.6 EAQ86184.1 - 5e-14 51.1 24.3 0.21 11.7 0.2 13.2 15 0 0 15 15 15 4 Leucine Rich repeat F-box-like PF12937.7 EAQ86184.1 - 1.2e-13 50.7 1.5 7.8e-13 48.1 0.1 2.5 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 EAQ86184.1 - 3.1e-08 33.8 14.0 1.8 9.1 0.1 7.7 6 2 1 7 7 7 3 Leucine Rich repeats (2 copies) F-box PF00646.33 EAQ86184.1 - 3.1e-05 23.7 0.0 8.9e-05 22.3 0.0 1.8 1 0 0 1 1 1 1 F-box domain Preseq_ALAS PF09029.10 EAQ86184.1 - 0.22 12.0 0.7 23 5.5 0.1 2.8 2 1 1 3 3 3 0 5-aminolevulinate synthase presequence SAM_Ste50p PF09235.10 EAQ86184.1 - 5.3 7.4 10.1 24 5.3 0.0 5.3 5 1 2 7 7 7 0 Ste50p, sterile alpha motif Glyco_hydro_35 PF01301.19 EAQ86185.1 - 3.6e-85 286.4 0.1 5.2e-85 285.8 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.9 EAQ86185.1 - 1.2e-54 184.8 0.0 2.2e-54 184.0 0.0 1.3 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.6 EAQ86185.1 - 1.1e-21 76.2 0.2 2.2e-21 75.2 0.2 1.6 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 BetaGal_dom4_5 PF13364.6 EAQ86185.1 - 6.8e-14 52.4 0.2 2.1e-13 50.9 0.2 1.7 1 0 0 1 1 1 1 Beta-galactosidase jelly roll domain Glyco_hydro_42 PF02449.15 EAQ86185.1 - 1.6e-06 27.7 0.1 0.0065 15.9 0.2 2.9 1 1 1 2 2 2 2 Beta-galactosidase Cellulase PF00150.18 EAQ86185.1 - 0.0022 17.5 0.0 0.0039 16.7 0.0 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) FISNA PF14484.6 EAQ86186.1 - 0.05 13.8 0.1 0.051 13.8 0.1 1.1 1 0 0 1 1 1 0 Fish-specific NACHT associated domain Sugar_tr PF00083.24 EAQ86187.1 - 2.2e-74 251.0 17.4 2.5e-74 250.8 17.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EAQ86187.1 - 9.7e-15 54.3 33.0 9.7e-15 54.3 33.0 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 EAQ86187.1 - 2.2 6.5 7.1 2.6 6.2 1.2 2.7 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family GST_N_4 PF17172.4 EAQ86188.1 - 8.2e-21 74.6 0.0 1.3e-20 74.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 EAQ86188.1 - 2.2e-08 33.7 0.0 1.5e-07 31.1 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 EAQ86188.1 - 0.011 16.0 0.0 0.03 14.6 0.0 1.7 2 0 0 2 2 2 0 Outer mitochondrial membrane transport complex protein GST_C_2 PF13410.6 EAQ86188.1 - 0.013 15.5 0.2 0.03 14.3 0.1 1.7 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain SDF PF00375.18 EAQ86189.1 - 3.6e-81 273.2 36.0 4.4e-81 272.9 36.0 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family Rax2 PF12768.7 EAQ86190.1 - 0.0034 16.9 0.0 0.0047 16.4 0.0 1.2 1 0 0 1 1 1 1 Cortical protein marker for cell polarity DUF347 PF03988.12 EAQ86190.1 - 0.0064 16.7 1.2 0.014 15.6 1.2 1.5 1 0 0 1 1 1 1 Repeat of Unknown Function (DUF347) SKG6 PF08693.10 EAQ86190.1 - 0.017 14.5 3.7 0.044 13.2 3.7 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Podoplanin PF05808.11 EAQ86190.1 - 0.38 10.8 7.3 0.25 11.4 5.0 1.8 2 1 0 2 2 2 0 Podoplanin SKG6 PF08693.10 EAQ86191.1 - 2.4e-05 23.7 0.8 4.3e-05 22.8 0.8 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Rax2 PF12768.7 EAQ86191.1 - 0.0028 17.2 0.0 0.0039 16.7 0.0 1.2 1 0 0 1 1 1 1 Cortical protein marker for cell polarity Podoplanin PF05808.11 EAQ86191.1 - 0.0034 17.5 0.3 0.0057 16.8 0.3 1.3 1 0 0 1 1 1 1 Podoplanin Granulin PF00396.18 EAQ86191.1 - 0.83 10.0 7.0 0.68 10.3 2.3 2.5 2 0 0 2 2 2 0 Granulin Gly_transf_sug PF04488.15 EAQ86192.1 - 1.4e-05 25.6 0.0 2.9e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Cyclase PF04199.13 EAQ86193.1 - 2.5e-16 60.1 0.2 3.4e-16 59.7 0.2 1.2 1 0 0 1 1 1 1 Putative cyclase FMO-like PF00743.19 EAQ86194.1 - 0.00014 20.4 0.0 0.00026 19.6 0.0 1.3 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 EAQ86194.1 - 0.0039 17.4 0.1 0.35 11.1 0.1 3.1 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain 2-Hacid_dh_C PF02826.19 EAQ86194.1 - 0.031 13.6 0.0 0.062 12.7 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Swi5 PF07061.11 EAQ86195.1 - 1.5e-20 73.0 1.0 2.4e-20 72.4 0.0 1.8 2 0 0 2 2 2 1 Swi5 DCP1 PF06058.13 EAQ86195.1 - 1.8e-07 31.1 0.0 5.7e-05 23.0 0.0 2.4 2 0 0 2 2 2 2 Dcp1-like decapping family Ferredoxin_N PF16947.5 EAQ86195.1 - 0.065 13.4 0.8 0.2 11.8 0.8 1.8 1 0 0 1 1 1 0 N-terminal region of 4Fe-4S ferredoxin iron-sulfur binding Ribonuclease PF00545.20 EAQ86196.1 - 1e-08 35.8 0.0 1.4e-08 35.4 0.0 1.2 1 0 0 1 1 1 1 ribonuclease Glyco_hydro_61 PF03443.14 EAQ86198.1 - 5.6e-59 199.5 0.2 6.6e-59 199.3 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 HET PF06985.11 EAQ86199.1 - 7.6e-14 52.3 0.0 2.2e-13 50.8 0.0 1.8 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Exo_endo_phos PF03372.23 EAQ86202.1 - 4.3e-08 33.0 0.0 9.3e-08 31.9 0.0 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF664 PF04978.12 EAQ86202.1 - 0.33 11.3 2.8 0.37 11.2 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF664) Beta-lactamase PF00144.24 EAQ86203.1 - 4.9e-36 124.6 0.0 1.2e-35 123.3 0.0 1.6 1 1 0 1 1 1 1 Beta-lactamase Fasciclin PF02469.22 EAQ86204.1 - 5.1e-39 133.4 0.1 9.7e-24 84.0 0.2 2.2 2 0 0 2 2 2 2 Fasciclin domain DUF3493 PF11998.8 EAQ86204.1 - 0.11 12.7 0.7 1.1 9.5 0.4 2.7 2 0 0 2 2 2 0 Low psii accumulation1 / Rep27 adh_short PF00106.25 EAQ86205.1 - 7.6e-21 74.5 0.0 1e-20 74.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EAQ86205.1 - 1.5e-13 50.9 0.0 2.6e-13 50.1 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EAQ86205.1 - 2e-09 37.6 0.1 2.8e-09 37.1 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EAQ86205.1 - 1.2e-05 24.9 0.0 1.5e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EAQ86205.1 - 0.0012 18.8 0.5 0.0023 17.9 0.4 1.6 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EAQ86205.1 - 0.0023 17.5 0.4 0.0033 17.0 0.4 1.2 1 0 0 1 1 1 1 NmrA-like family HeLo PF14479.6 EAQ86206.1 - 2.7e-17 63.3 0.0 4.8e-17 62.5 0.0 1.4 1 0 0 1 1 1 1 Prion-inhibition and propagation NACHT PF05729.12 EAQ86206.1 - 7.2e-09 35.8 0.6 3e-08 33.8 0.1 2.2 2 1 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 EAQ86206.1 - 2.9e-07 31.0 1.1 1.1e-06 29.1 0.0 2.4 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 EAQ86206.1 - 0.00025 21.3 0.0 0.00061 20.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 EAQ86206.1 - 0.0018 18.2 0.0 0.11 12.4 0.0 2.2 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea Viral_helicase1 PF01443.18 EAQ86206.1 - 0.0029 17.4 0.0 0.0067 16.2 0.0 1.6 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.22 EAQ86206.1 - 0.021 14.0 0.0 0.046 12.9 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_30 PF13604.6 EAQ86206.1 - 0.023 14.4 0.0 0.046 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 EAQ86206.1 - 0.037 13.8 0.0 0.061 13.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 EAQ86206.1 - 0.047 13.6 0.0 0.088 12.7 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 EAQ86206.1 - 0.082 12.7 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 EAQ86206.1 - 0.11 13.0 0.0 0.23 12.0 0.0 1.4 1 0 0 1 1 1 0 ABC transporter RNA_helicase PF00910.22 EAQ86206.1 - 0.12 12.8 0.0 0.25 11.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.6 EAQ86206.1 - 0.17 12.1 0.3 0.56 10.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain FAD_binding_4 PF01565.23 EAQ86207.1 - 8.7e-19 67.6 3.2 1.7e-18 66.7 3.2 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EAQ86207.1 - 2.6e-11 43.4 0.0 5.9e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like DDE_1 PF03184.19 EAQ86209.1 - 2.1e-18 66.6 0.0 3.1e-18 66.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 EAQ86209.1 - 0.0072 16.1 0.0 0.02 14.7 0.0 1.7 1 0 0 1 1 1 1 DDE superfamily endonuclease WES_acyltransf PF03007.16 EAQ86209.1 - 0.2 11.4 2.2 0.38 10.5 2.2 1.4 1 0 0 1 1 1 0 Wax ester synthase-like Acyl-CoA acyltransferase domain VCBS PF13517.6 EAQ86210.1 - 1.4 9.5 5.9 16 6.1 5.9 2.8 1 1 0 1 1 1 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Glyco_hydro_47 PF01532.20 EAQ86211.1 - 5.5e-160 533.2 0.0 8.2e-158 526.0 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 47 RVT_1 PF00078.27 EAQ86212.1 - 1.2e-15 57.7 0.0 1.7e-15 57.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 EAQ86212.1 - 0.02 15.6 0.0 0.042 14.6 0.0 1.5 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase TauD PF02668.16 EAQ86213.1 - 9.9e-31 107.5 0.2 1.4e-30 107.1 0.2 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family LssY_C PF14067.6 EAQ86213.1 - 0.044 13.3 0.0 0.33 10.5 0.0 2.0 2 0 0 2 2 2 0 LssY C-terminus DUF1996 PF09362.10 EAQ86214.1 - 4.5e-50 170.8 3.3 6.1e-50 170.4 3.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) AltA1 PF16541.5 EAQ86215.1 - 2.6e-29 102.3 1.7 3.6e-29 101.8 1.7 1.2 1 0 0 1 1 1 1 Alternaria alternata allergen 1 Patatin PF01734.22 EAQ86217.1 - 8.8e-21 75.0 0.1 1.6e-20 74.1 0.1 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase Ank_4 PF13637.6 EAQ86217.1 - 2.8e-06 27.7 0.1 8.2e-06 26.3 0.1 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAQ86217.1 - 0.0002 21.9 0.0 0.00074 20.1 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) zf-B_box PF00643.24 EAQ86217.1 - 0.00039 20.5 4.2 0.00039 20.5 4.2 2.5 2 0 0 2 2 2 1 B-box zinc finger Ank_3 PF13606.6 EAQ86217.1 - 0.021 15.3 0.1 0.2 12.3 0.0 2.6 2 0 0 2 2 2 0 Ankyrin repeat Ank PF00023.30 EAQ86217.1 - 0.034 14.6 0.4 0.2 12.2 0.1 2.5 3 0 0 3 3 3 0 Ankyrin repeat Ank_5 PF13857.6 EAQ86217.1 - 0.14 12.5 0.0 0.42 11.0 0.0 1.8 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Pept_tRNA_hydro PF01195.19 EAQ86219.1 - 7.4e-24 84.6 0.0 8.9e-24 84.4 0.0 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase Cren7 PF11520.8 EAQ86219.1 - 0.073 13.0 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 Chromatin protein Cren7 HTH_Tnp_Tc3_2 PF01498.18 EAQ86220.1 - 0.00028 21.1 0.1 0.00062 20.0 0.1 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 EAQ86220.1 - 0.029 14.1 0.0 0.045 13.5 0.0 1.4 1 0 0 1 1 1 0 DDE superfamily endonuclease TniQ PF06527.11 EAQ86220.1 - 0.062 14.0 0.9 0.16 12.7 0.9 1.7 1 1 0 1 1 1 0 TniQ BAR PF03114.18 EAQ86221.1 - 2.6e-67 227.0 3.3 3.4e-67 226.6 3.3 1.2 1 0 0 1 1 1 1 BAR domain CP12 PF02672.15 EAQ86221.1 - 0.0036 18.0 0.7 0.022 15.5 0.0 2.6 3 1 1 4 4 4 1 CP12 domain BAR PF03114.18 EAQ86222.1 - 1.4e-54 185.3 3.0 1.8e-54 184.9 3.0 1.1 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.9 EAQ86222.1 - 2.6e-05 23.5 2.4 3.9e-05 22.9 2.4 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking OmpH PF03938.14 EAQ86222.1 - 6.3 7.1 9.5 2.7 8.3 6.3 1.8 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Cyclin_C_2 PF16899.5 EAQ86223.1 - 1.7e-36 124.8 0.0 1.2e-33 115.5 0.0 2.3 2 0 0 2 2 2 2 Cyclin C-terminal domain Cyclin_N PF00134.23 EAQ86223.1 - 5.5e-06 26.1 0.0 1.2e-05 25.0 0.0 1.6 2 0 0 2 2 2 1 Cyclin, N-terminal domain UQ_con PF00179.26 EAQ86224.1 - 5e-16 58.6 0.0 1.1e-15 57.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Ammonium_transp PF00909.21 EAQ86225.1 - 1.2e-120 402.9 27.8 1.4e-120 402.7 27.8 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Phage_holin_2_1 PF04971.12 EAQ86225.1 - 1.3 9.1 9.2 2.2 8.4 0.5 3.7 3 0 0 3 3 3 0 Bacteriophage P21 holin S Con-6 PF10346.9 EAQ86228.1 - 6.6e-16 58.0 1.1 6.6e-16 58.0 1.1 2.4 3 0 0 3 3 3 1 Conidiation protein 6 DLH PF01738.18 EAQ86229.1 - 6.3e-12 45.5 0.0 9.8e-12 44.9 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 EAQ86229.1 - 0.00039 21.1 5.7 0.0014 19.3 5.6 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 EAQ86229.1 - 0.0023 17.4 0.2 0.061 12.8 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family 2-Hacid_dh_C PF02826.19 EAQ86231.1 - 1e-36 126.0 0.0 1.7e-36 125.3 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EAQ86231.1 - 2.9e-10 39.9 0.0 4.1e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EAQ86231.1 - 2.9e-05 24.3 0.0 6.2e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Putative_PNPOx PF01243.20 EAQ86231.1 - 0.017 15.3 0.0 0.065 13.4 0.0 2.0 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase F420_oxidored PF03807.17 EAQ86231.1 - 0.025 15.1 0.0 0.058 14.0 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Podoplanin PF05808.11 EAQ86232.1 - 9.4e-05 22.6 1.3 0.00017 21.8 1.3 1.3 1 0 0 1 1 1 1 Podoplanin CbtA PF09490.10 EAQ86232.1 - 0.0066 16.2 0.2 0.011 15.5 0.2 1.2 1 0 0 1 1 1 1 Probable cobalt transporter subunit (CbtA) Beta-APP PF03494.13 EAQ86232.1 - 0.044 13.6 4.5 0.092 12.6 4.5 1.5 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) DUF4366 PF14283.6 EAQ86232.1 - 0.091 12.8 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Gram_pos_anchor PF00746.21 EAQ86232.1 - 0.22 11.5 1.3 0.52 10.3 1.3 1.6 1 0 0 1 1 1 0 LPXTG cell wall anchor motif Gly-zipper_Omp PF13488.6 EAQ86232.1 - 0.23 11.5 10.2 0.52 10.3 10.2 1.6 1 0 0 1 1 1 0 Glycine zipper Formyl_trans_N PF00551.19 EAQ86233.1 - 2.8e-38 131.5 0.0 3.5e-38 131.2 0.0 1.1 1 0 0 1 1 1 1 Formyl transferase MannoseP_isomer PF01050.18 EAQ86233.1 - 0.054 13.4 0.1 0.11 12.4 0.1 1.5 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase F-box-like PF12937.7 EAQ86234.1 - 0.0023 17.8 0.1 0.0095 15.8 0.1 2.1 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 EAQ86234.1 - 0.032 14.7 3.9 8.4 7.0 0.0 4.6 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) F-box PF00646.33 EAQ86234.1 - 0.094 12.6 0.3 3.5 7.6 0.0 2.8 3 0 0 3 3 3 0 F-box domain NOA36 PF06524.12 EAQ86234.1 - 1.1 8.6 6.1 1.4 8.2 6.1 1.2 1 0 0 1 1 1 0 NOA36 protein NmrA PF05368.13 EAQ86236.1 - 0.0055 16.3 0.1 0.022 14.3 0.0 1.8 1 1 0 2 2 2 1 NmrA-like family HHH PF00633.23 EAQ86236.1 - 0.14 12.1 0.3 0.74 9.8 0.0 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix motif Glyco_hydro_64 PF16483.5 EAQ86239.1 - 2.4e-109 366.0 0.0 4.8e-69 233.4 0.0 2.0 2 0 0 2 2 2 2 Beta-1,3-glucanase LEA_2 PF03168.13 EAQ86239.1 - 0.82 10.2 2.3 36 5.0 0.2 2.7 3 0 0 3 3 3 0 Late embryogenesis abundant protein Sulfotransfer_4 PF17784.1 EAQ86240.1 - 5.1e-63 212.8 0.0 6.3e-63 212.5 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 EAQ86240.1 - 0.032 14.6 0.1 0.17 12.3 0.0 2.1 1 1 0 2 2 2 0 Sulfotransferase family ABC_tran PF00005.27 EAQ86241.1 - 5.6e-35 120.8 0.0 6.7e-25 88.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EAQ86241.1 - 5.7e-24 85.2 15.6 8.5e-20 71.5 5.0 2.5 2 1 1 3 3 3 2 ABC transporter transmembrane region AAA_21 PF13304.6 EAQ86241.1 - 4.4e-10 39.9 2.0 0.0051 16.6 0.0 4.2 3 1 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EAQ86241.1 - 3.7e-07 30.2 0.4 0.0028 17.6 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase SMC_N PF02463.19 EAQ86241.1 - 6.6e-07 29.0 1.5 0.0047 16.4 0.1 3.4 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EAQ86241.1 - 7.4e-07 28.8 1.9 0.0027 17.4 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 EAQ86241.1 - 2.2e-06 28.0 2.3 0.028 14.7 0.2 3.0 2 1 0 2 2 2 2 AAA domain AAA_23 PF13476.6 EAQ86241.1 - 7.7e-06 26.6 0.8 0.00093 19.7 0.3 2.4 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 EAQ86241.1 - 1.4e-05 24.7 1.8 0.046 13.3 0.2 2.4 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain FtsK_SpoIIIE PF01580.18 EAQ86241.1 - 1.6e-05 24.4 0.4 0.085 12.2 0.1 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family Dynamin_N PF00350.23 EAQ86241.1 - 2.1e-05 24.7 0.6 0.0034 17.5 0.1 2.3 2 0 0 2 2 2 1 Dynamin family T2SSE PF00437.20 EAQ86241.1 - 4e-05 22.8 0.1 0.065 12.3 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_15 PF13175.6 EAQ86241.1 - 4.1e-05 23.5 0.0 0.26 11.0 0.1 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_16 PF13191.6 EAQ86241.1 - 4.3e-05 23.9 0.0 0.34 11.3 0.0 2.9 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 EAQ86241.1 - 4.6e-05 23.5 0.0 0.019 15.0 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_33 PF13671.6 EAQ86241.1 - 5.3e-05 23.4 0.0 0.32 11.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain Septin PF00735.18 EAQ86241.1 - 0.00028 20.2 0.1 0.46 9.7 0.0 2.2 2 0 0 2 2 2 2 Septin AAA_18 PF13238.6 EAQ86241.1 - 0.0016 19.0 0.0 2.5 8.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain Roc PF08477.13 EAQ86241.1 - 0.0024 18.1 1.0 2 8.6 0.1 3.3 3 0 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase MobB PF03205.14 EAQ86241.1 - 0.0026 17.7 1.0 1.3 8.9 0.2 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B IstB_IS21 PF01695.17 EAQ86241.1 - 0.0054 16.5 0.3 18 5.0 0.0 4.0 4 0 0 4 4 4 0 IstB-like ATP binding protein AAA_25 PF13481.6 EAQ86241.1 - 0.0061 16.2 0.2 2.6 7.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EAQ86241.1 - 0.0079 16.5 2.5 2.2 8.6 0.1 2.8 3 0 0 3 3 2 1 AAA domain Viral_helicase1 PF01443.18 EAQ86241.1 - 0.011 15.4 0.4 1.6 8.4 0.0 2.8 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 EAQ86241.1 - 0.012 15.4 1.7 2.5 7.8 0.1 2.9 2 1 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EAQ86241.1 - 0.013 15.1 0.8 0.7 9.4 0.1 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region NACHT PF05729.12 EAQ86241.1 - 0.014 15.3 2.8 1.8 8.5 0.0 3.0 3 0 0 3 3 3 0 NACHT domain ATP_bind_1 PF03029.17 EAQ86241.1 - 0.015 15.1 0.6 3.9 7.2 0.1 2.8 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_24 PF13479.6 EAQ86241.1 - 0.018 14.8 0.2 3.1 7.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 EAQ86241.1 - 0.018 15.5 0.0 7.8 6.9 0.0 3.3 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) DUF87 PF01935.17 EAQ86241.1 - 0.02 15.0 1.5 5.2 7.1 0.1 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_5 PF07728.14 EAQ86241.1 - 0.022 14.8 1.0 2.8 7.9 0.0 2.8 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 EAQ86241.1 - 0.036 14.1 0.2 2.2 8.3 0.0 2.7 3 0 0 3 3 2 0 AAA domain TrwB_AAD_bind PF10412.9 EAQ86241.1 - 0.045 12.6 0.8 6.2 5.6 0.1 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain RNA_helicase PF00910.22 EAQ86241.1 - 0.055 13.9 0.9 18 5.7 0.2 2.8 2 1 0 2 2 2 0 RNA helicase AAA_28 PF13521.6 EAQ86241.1 - 0.059 13.6 0.9 12 6.1 0.1 2.5 2 0 0 2 2 2 0 AAA domain GTP_EFTU PF00009.27 EAQ86241.1 - 0.077 12.5 0.5 0.74 9.3 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Zeta_toxin PF06414.12 EAQ86241.1 - 0.096 11.9 0.2 3.2 7.0 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin NB-ARC PF00931.22 EAQ86241.1 - 0.11 11.6 0.2 2.5 7.2 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain Adeno_IVa2 PF02456.15 EAQ86241.1 - 0.13 11.0 0.3 0.24 10.2 0.0 1.5 2 0 0 2 2 1 0 Adenovirus IVa2 protein ATP-synt_ab PF00006.25 EAQ86241.1 - 0.13 11.9 0.0 2.6 7.6 0.0 2.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain UL42 PF17638.2 EAQ86241.1 - 0.14 12.2 0.7 0.28 11.2 0.0 1.8 2 0 0 2 2 1 0 HCMV UL42 TsaE PF02367.17 EAQ86241.1 - 0.15 12.1 0.2 10 6.2 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Pox_A32 PF04665.12 EAQ86241.1 - 0.15 11.5 0.7 4.3 6.7 0.1 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein ATPase_2 PF01637.18 EAQ86241.1 - 0.16 11.8 0.1 14 5.5 0.0 2.3 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea PRK PF00485.18 EAQ86241.1 - 0.18 11.6 0.4 2.7 7.7 0.1 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family MFS_1 PF07690.16 EAQ86242.1 - 8.1e-05 21.7 2.5 0.0011 18.0 2.5 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_3 PF05977.13 EAQ86242.1 - 0.032 12.6 0.0 0.048 12.1 0.0 1.2 1 0 0 1 1 1 0 Transmembrane secretion effector Methyltransf_23 PF13489.6 EAQ86243.1 - 1.5e-06 28.1 0.0 2.6e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAQ86243.1 - 6.3e-06 26.8 0.0 1.9e-05 25.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAQ86243.1 - 4.3e-05 23.4 0.0 7.4e-05 22.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 EAQ86243.1 - 0.00019 22.4 0.0 0.00057 20.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EAQ86243.1 - 0.0039 17.8 0.0 0.015 16.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EAQ86243.1 - 0.0043 16.8 0.0 0.0067 16.2 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.18 EAQ86243.1 - 0.021 14.2 0.0 0.035 13.4 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_3 PF01596.17 EAQ86243.1 - 0.059 12.5 0.0 0.091 11.9 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase RrnaAD PF00398.20 EAQ86243.1 - 0.25 10.4 0.0 0.41 9.7 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase DUF3328 PF11807.8 EAQ86244.1 - 4.5e-27 95.3 2.5 2.7e-26 92.7 2.5 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) CSD2 PF17876.1 EAQ86246.1 - 0.0059 16.8 4.0 82 3.5 0.2 5.0 4 1 1 5 5 5 0 Cold shock domain HisK_N PF09385.10 EAQ86246.1 - 0.012 15.5 17.2 20 5.2 0.2 6.0 1 1 5 6 6 6 0 Histidine kinase N terminal DUF5415 PF17436.2 EAQ86246.1 - 0.67 10.1 9.4 42 4.3 0.0 4.6 5 0 0 5 5 5 0 Family of unknown function (DUF5415) SET PF00856.28 EAQ86247.1 - 1.2e-09 38.8 0.0 4.2e-08 33.8 0.0 2.6 2 1 0 2 2 2 1 SET domain PPTA PF01239.22 EAQ86247.1 - 0.27 11.0 1.6 0.41 10.4 0.8 1.7 2 0 0 2 2 2 0 Protein prenyltransferase alpha subunit repeat FMN_bind_2 PF04299.12 EAQ86248.1 - 5.4e-57 192.2 0.0 6.4e-57 191.9 0.0 1.1 1 0 0 1 1 1 1 Putative FMN-binding domain UvrD_C_2 PF13538.6 EAQ86250.1 - 0.016 15.0 0.0 0.047 13.5 0.0 1.8 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain CFEM PF05730.11 EAQ86251.1 - 3e-12 46.5 7.2 4.2e-12 46.0 7.2 1.2 1 0 0 1 1 1 1 CFEM domain p450 PF00067.22 EAQ86255.1 - 2.1e-91 307.0 0.0 2.4e-91 306.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ParA PF10609.9 EAQ86257.1 - 1.4e-93 312.9 0.0 1.7e-93 312.6 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 EAQ86257.1 - 1.8e-11 44.2 0.0 4e-11 43.1 0.0 1.5 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.11 EAQ86257.1 - 3.6e-07 29.7 0.0 5.7e-06 25.8 0.0 2.0 2 0 0 2 2 2 1 ATPase MipZ AAA_31 PF13614.6 EAQ86257.1 - 2.2e-06 27.7 1.0 3.7e-05 23.7 0.9 2.1 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.15 EAQ86257.1 - 4.9e-06 26.0 1.1 8.4e-06 25.2 0.4 1.6 2 0 0 2 2 2 1 Anion-transporting ATPase MeaB PF03308.16 EAQ86257.1 - 0.00031 19.8 0.5 0.00049 19.2 0.5 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_26 PF13500.6 EAQ86257.1 - 0.0026 17.6 0.4 2.6 7.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 EAQ86257.1 - 0.0035 16.9 0.3 0.0073 15.9 0.3 1.5 1 0 0 1 1 1 1 AAA domain CBP_BcsQ PF06564.12 EAQ86257.1 - 0.0047 16.4 0.5 0.014 14.9 0.5 1.8 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ APS_kinase PF01583.20 EAQ86257.1 - 0.016 15.1 0.1 0.026 14.4 0.1 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_30 PF13604.6 EAQ86257.1 - 0.045 13.5 0.0 5.2 6.7 0.1 2.1 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EAQ86257.1 - 0.049 14.0 0.4 0.11 12.9 0.3 1.5 2 0 0 2 2 2 0 AAA ATPase domain Zeta_toxin PF06414.12 EAQ86257.1 - 0.057 12.7 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin IstB_IS21 PF01695.17 EAQ86257.1 - 0.16 11.7 0.0 0.56 9.9 0.1 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein RsgA_GTPase PF03193.16 EAQ86257.1 - 0.3 11.0 2.9 0.3 11.0 1.5 1.6 2 0 0 2 2 2 0 RsgA GTPase NB-ARC PF00931.22 EAQ86257.1 - 0.35 10.0 0.6 0.49 9.5 0.6 1.2 1 0 0 1 1 1 0 NB-ARC domain APH PF01636.23 EAQ86258.1 - 2.9e-06 27.4 0.0 5.6e-06 26.4 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EAQ86258.1 - 0.067 12.8 0.0 0.14 11.7 0.0 1.5 2 0 0 2 2 2 0 Choline/ethanolamine kinase SAM_decarbox PF01536.16 EAQ86259.1 - 7.2e-136 452.9 0.0 8.7e-136 452.6 0.0 1.1 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase Ank_4 PF13637.6 EAQ86260.1 - 2.7e-10 40.6 1.3 0.063 13.9 0.0 5.9 5 2 3 8 8 8 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAQ86260.1 - 1.2e-09 38.6 0.0 0.006 17.2 0.0 5.5 5 1 1 6 6 6 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAQ86260.1 - 5.8e-06 26.3 0.6 0.93 10.3 0.0 6.2 7 1 1 8 8 8 2 Ankyrin repeat Ank_5 PF13857.6 EAQ86260.1 - 0.00013 22.2 1.5 0.83 10.1 0.0 5.1 4 2 2 6 6 6 1 Ankyrin repeats (many copies) Ank PF00023.30 EAQ86260.1 - 0.0057 17.1 0.0 21 5.8 0.0 4.9 5 1 0 5 5 5 1 Ankyrin repeat Pro_CA PF00484.19 EAQ86261.1 - 1.7e-14 54.4 0.1 3.4e-14 53.4 0.1 1.5 1 1 0 1 1 1 1 Carbonic anhydrase TOM13 PF08219.11 EAQ86262.1 - 3.7e-33 113.3 0.0 1.3e-32 111.6 0.0 1.9 1 0 0 1 1 1 1 Outer membrane protein TOM13 60KD_IMP PF02096.20 EAQ86262.1 - 4.2e-14 52.8 6.5 4.2e-14 52.8 6.5 1.8 2 0 0 2 2 2 1 60Kd inner membrane protein SEP PF08059.13 EAQ86263.1 - 9.2e-24 83.8 0.5 2.3e-23 82.6 0.0 1.9 2 0 0 2 2 2 1 SEP domain UBA_4 PF14555.6 EAQ86263.1 - 3.2e-12 46.1 0.3 5.3e-12 45.4 0.3 1.4 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.20 EAQ86263.1 - 1.8e-05 24.8 0.0 3.2e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 UBX domain Spt5_N PF11942.8 EAQ86263.1 - 0.046 14.7 6.9 0.14 13.2 6.9 1.8 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal TAP_C PF03943.13 EAQ86263.1 - 0.19 11.4 0.1 0.33 10.6 0.1 1.3 1 0 0 1 1 1 0 TAP C-terminal domain Gtr1_RagA PF04670.12 EAQ86264.1 - 2.1e-99 331.6 0.0 2.8e-99 331.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 EAQ86264.1 - 3.7e-09 36.3 0.1 5.8e-09 35.7 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EAQ86264.1 - 4.4e-09 36.6 0.0 1e-08 35.4 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EAQ86264.1 - 1.7e-08 34.3 0.1 2.8e-08 33.5 0.1 1.3 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 EAQ86264.1 - 2.3e-07 30.9 0.0 4.4e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EAQ86264.1 - 0.00029 20.8 1.4 0.058 13.3 0.1 2.3 2 0 0 2 2 2 2 RsgA GTPase G-alpha PF00503.20 EAQ86264.1 - 0.0013 18.0 2.2 0.65 9.1 0.8 2.7 2 1 1 3 3 3 2 G-protein alpha subunit AAA_29 PF13555.6 EAQ86264.1 - 0.0034 17.1 0.6 0.034 13.9 0.2 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain ABC_tran PF00005.27 EAQ86264.1 - 0.012 16.2 0.3 0.027 15.0 0.2 1.6 1 1 0 1 1 1 0 ABC transporter DUF815 PF05673.13 EAQ86264.1 - 0.019 14.1 0.1 0.019 14.1 0.1 1.7 2 0 0 2 2 1 0 Protein of unknown function (DUF815) Sigma54_activat PF00158.26 EAQ86264.1 - 0.1 12.3 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain Arylsulfotran_2 PF14269.6 EAQ86266.1 - 9.7e-73 245.1 2.2 1.4e-72 244.6 2.2 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 EAQ86266.1 - 6.8e-19 68.0 0.6 2.2e-17 63.0 0.6 2.2 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) MFS_1 PF07690.16 EAQ86267.1 - 4.6e-42 144.2 44.8 1.6e-41 142.4 44.8 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EAQ86267.1 - 1.1e-13 50.9 25.8 8.6e-12 44.6 16.2 2.4 2 0 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.13 EAQ86267.1 - 7.5e-08 31.3 9.8 7.5e-08 31.3 9.8 2.0 1 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Ank_2 PF12796.7 EAQ86268.1 - 3e-42 143.1 15.8 9e-10 39.0 0.0 10.6 7 2 5 12 12 12 11 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAQ86268.1 - 3.3e-26 91.3 9.9 3.2e-07 30.8 0.0 12.8 8 4 5 13 13 13 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAQ86268.1 - 2.5e-21 73.5 11.7 0.12 13.0 0.0 14.8 14 1 1 15 15 15 4 Ankyrin repeat Ank PF00023.30 EAQ86268.1 - 3e-13 49.5 23.9 0.011 16.1 0.6 13.7 15 0 0 15 15 15 3 Ankyrin repeat Ank_5 PF13857.6 EAQ86268.1 - 9.6e-11 41.7 6.4 0.013 15.8 0.0 7.7 7 1 1 8 8 8 3 Ankyrin repeats (many copies) NADH-G_4Fe-4S_3 PF10588.9 EAQ86268.1 - 0.27 10.8 1.0 4 7.1 0.3 2.8 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Zn_clus PF00172.18 EAQ86269.1 - 2.8e-06 27.3 8.7 5.5e-06 26.4 8.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Integrase_H2C2 PF17921.1 EAQ86269.1 - 0.016 15.3 3.5 0.31 11.2 0.3 2.9 3 0 0 3 3 3 0 Integrase zinc binding domain PBP PF01161.20 EAQ86270.1 - 9.8e-10 38.9 0.8 2.5e-09 37.6 0.8 1.7 1 1 0 1 1 1 1 Phosphatidylethanolamine-binding protein Erythro_esteras PF05139.14 EAQ86271.1 - 4.1e-126 421.4 0.6 4.9e-126 421.2 0.6 1.1 1 0 0 1 1 1 1 Erythromycin esterase Con-6 PF10346.9 EAQ86273.1 - 1.8e-15 56.7 0.1 1.8e-15 56.7 0.1 1.7 2 0 0 2 2 2 1 Conidiation protein 6 SpoIIIAH PF12685.7 EAQ86273.1 - 0.14 11.9 1.5 0.16 11.8 1.5 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein Med15 PF09606.10 EAQ86275.1 - 0.0033 16.2 22.3 0.048 12.3 23.4 1.9 2 0 0 2 2 2 1 ARC105 or Med15 subunit of Mediator complex non-fungal DUF2722 PF10846.8 EAQ86275.1 - 0.004 16.2 22.1 0.0056 15.7 22.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) DDHD PF02862.17 EAQ86275.1 - 0.0041 17.3 1.3 0.006 16.8 1.3 1.2 1 0 0 1 1 1 1 DDHD domain TFIIA PF03153.13 EAQ86275.1 - 0.0078 16.3 22.5 0.011 15.8 22.5 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 EAQ86275.1 - 0.014 15.0 32.6 0.02 14.5 32.6 1.1 1 0 0 1 1 1 0 Spt20 family Ndc1_Nup PF09531.10 EAQ86275.1 - 0.02 13.6 4.0 0.028 13.1 4.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Suf PF05843.14 EAQ86275.1 - 0.026 14.5 7.3 0.042 13.8 7.3 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF913 PF06025.12 EAQ86275.1 - 0.026 13.5 2.6 0.037 13.0 2.6 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) EPL1 PF10513.9 EAQ86275.1 - 0.027 14.8 6.5 0.052 13.9 6.5 1.4 1 0 0 1 1 1 0 Enhancer of polycomb-like PAT1 PF09770.9 EAQ86275.1 - 0.037 12.3 13.6 0.047 12.0 13.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Pex14_N PF04695.13 EAQ86275.1 - 0.055 14.1 11.1 0.056 14.1 9.8 1.6 2 0 0 2 2 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4834 PF16118.5 EAQ86275.1 - 0.083 13.9 11.7 0.24 12.4 11.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Pannexin_like PF12534.8 EAQ86275.1 - 0.088 11.9 3.0 0.13 11.4 3.0 1.1 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 DUF4175 PF13779.6 EAQ86275.1 - 0.1 10.5 22.7 0.17 9.7 22.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) EOS1 PF12326.8 EAQ86275.1 - 0.14 12.1 0.7 0.23 11.4 0.7 1.4 1 0 0 1 1 1 0 N-glycosylation protein V_ATPase_I PF01496.19 EAQ86275.1 - 0.17 9.7 5.4 0.22 9.4 5.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CDC45 PF02724.14 EAQ86275.1 - 0.23 9.7 6.0 0.32 9.2 6.0 1.1 1 0 0 1 1 1 0 CDC45-like protein MMR1 PF08505.10 EAQ86275.1 - 0.23 11.7 10.4 0.35 11.1 10.4 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein eIF-3_zeta PF05091.12 EAQ86275.1 - 0.29 10.1 13.4 0.4 9.6 13.4 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) ABC2_membrane_2 PF12679.7 EAQ86275.1 - 0.34 10.1 1.2 0.55 9.5 0.1 1.9 2 0 0 2 2 2 0 ABC-2 family transporter protein G0-G1_switch_2 PF15103.6 EAQ86275.1 - 0.41 11.1 4.6 0.78 10.2 4.6 1.4 1 0 0 1 1 1 0 G0/G1 switch protein 2 CPSF100_C PF13299.6 EAQ86275.1 - 0.46 10.7 7.1 0.84 9.8 7.1 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal PepSY_TM PF03929.16 EAQ86275.1 - 0.56 9.8 2.7 1.2 8.8 2.7 1.5 1 0 0 1 1 1 0 PepSY-associated TM region SLC12 PF03522.15 EAQ86275.1 - 0.61 9.0 7.9 0.84 8.6 7.9 1.1 1 0 0 1 1 1 0 Solute carrier family 12 CLN3 PF02487.17 EAQ86275.1 - 0.76 8.7 5.4 1.3 8.0 5.4 1.3 1 0 0 1 1 1 0 CLN3 protein TERB2 PF15101.6 EAQ86275.1 - 0.81 9.7 15.0 1.4 8.9 15.0 1.3 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF775 PF05603.12 EAQ86275.1 - 1.1 8.7 8.8 1.8 8.1 8.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF775) EIIBC-GUT_N PF03612.14 EAQ86275.1 - 1.2 8.9 7.5 2 8.1 7.5 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Neur_chan_memb PF02932.16 EAQ86275.1 - 1.2 9.1 6.0 2.1 8.3 6.0 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SpoIIP PF07454.11 EAQ86275.1 - 1.3 8.5 10.9 2 7.8 10.9 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Androgen_recep PF02166.16 EAQ86275.1 - 1.3 7.8 25.0 2.1 7.1 25.0 1.3 1 0 0 1 1 1 0 Androgen receptor Presenilin PF01080.17 EAQ86275.1 - 1.4 7.7 12.2 2 7.1 12.2 1.2 1 0 0 1 1 1 0 Presenilin Serinc PF03348.15 EAQ86275.1 - 1.7 7.5 3.7 2.4 7.0 3.7 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF1980 PF09323.10 EAQ86275.1 - 2 8.3 8.4 4.6 7.1 8.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) MCU PF04678.13 EAQ86275.1 - 2.3 8.3 8.1 3.3 7.8 8.1 1.2 1 0 0 1 1 1 0 Mitochondrial calcium uniporter SID-1_RNA_chan PF13965.6 EAQ86275.1 - 2.4 6.4 3.7 3.4 6.0 3.7 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Folliculin PF11704.8 EAQ86275.1 - 2.5 8.0 7.2 4.1 7.2 7.2 1.3 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport Band_3_cyto PF07565.13 EAQ86275.1 - 3 7.6 8.6 4.6 7.0 8.6 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF4407 PF14362.6 EAQ86275.1 - 4.1 6.7 15.5 6.5 6.0 15.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4746 PF15928.5 EAQ86275.1 - 4.4 6.6 9.2 5 6.4 8.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) FAM176 PF14851.6 EAQ86275.1 - 5.9 6.6 6.8 12 5.5 6.8 1.5 1 0 0 1 1 1 0 FAM176 family ALMT PF11744.8 EAQ86275.1 - 6 5.6 9.7 14 4.3 7.8 1.9 2 0 0 2 2 2 0 Aluminium activated malate transporter DUF2828 PF11443.8 EAQ86275.1 - 6.4 4.7 9.8 9.1 4.2 9.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Connexin PF00029.19 EAQ86275.1 - 6.9 6.3 8.2 13 5.5 8.2 1.3 1 0 0 1 1 1 0 Connexin DivIC PF04977.15 EAQ86275.1 - 8 6.3 20.9 11 5.8 17.5 2.6 2 0 0 2 2 2 0 Septum formation initiator CE2_N PF17996.1 EAQ86277.1 - 9.8e-20 70.6 0.0 1.8e-19 69.7 0.0 1.4 1 0 0 1 1 1 1 Carbohydrate esterase 2 N-terminal Lipase_GDSL_2 PF13472.6 EAQ86277.1 - 2.3e-13 50.9 1.0 2.3e-13 50.9 1.0 1.6 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family CBM_1 PF00734.18 EAQ86277.1 - 3.5e-13 49.2 11.2 1e-12 47.8 11.2 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain Lipase_GDSL PF00657.22 EAQ86277.1 - 1.3e-07 31.8 0.2 3.2e-07 30.5 0.0 1.7 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase Aldo_ket_red PF00248.21 EAQ86278.1 - 0.00051 19.3 0.0 0.00054 19.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Peptidase_C48 PF02902.19 EAQ86280.1 - 2.8e-06 27.4 1.6 2.8e-06 27.3 0.1 1.7 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain VARLMGL PF14383.6 EAQ86280.1 - 0.067 12.7 0.0 0.21 11.2 0.0 1.8 1 0 0 1 1 1 0 DUF761-associated sequence motif PSK_trans_fac PF07704.11 EAQ86280.1 - 0.65 10.8 6.8 3.7 8.4 6.8 2.4 1 0 0 1 1 1 0 Rv0623-like transcription factor OPT PF03169.15 EAQ86281.1 - 1.7e-154 515.8 45.5 2.2e-154 515.5 45.5 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DEAD PF00270.29 EAQ86281.1 - 1.2e-40 139.2 0.0 2.1e-40 138.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EAQ86281.1 - 4e-21 75.4 0.0 5.3e-20 71.8 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EAQ86281.1 - 7.8e-08 32.5 0.0 1.4e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 EAQ86281.1 - 0.0082 16.5 0.0 0.014 15.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain ERCC3_RAD25_C PF16203.5 EAQ86281.1 - 0.013 14.7 0.0 0.027 13.7 0.0 1.4 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase DUF2075 PF09848.9 EAQ86281.1 - 0.042 13.1 0.0 0.11 11.7 0.0 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 EAQ86281.1 - 0.07 13.4 0.0 0.18 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain SecA_DEAD PF07517.14 EAQ86281.1 - 0.18 11.1 0.3 0.39 10.0 0.0 1.6 2 0 0 2 2 2 0 SecA DEAD-like domain Acetyltransf_1 PF00583.25 EAQ86282.1 - 4e-08 33.5 0.0 6.4e-08 32.8 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EAQ86282.1 - 2.2e-06 28.0 0.7 1e-05 25.8 0.2 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EAQ86282.1 - 3.1e-06 27.2 0.1 5.8e-06 26.3 0.0 1.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EAQ86282.1 - 0.0055 16.6 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 EAQ86282.1 - 0.13 12.3 0.0 1.2 9.2 0.0 2.2 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain FAD_binding_4 PF01565.23 EAQ86284.1 - 3.7e-19 68.9 0.9 9.9e-19 67.5 0.9 1.8 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EAQ86284.1 - 3.8e-12 46.1 1.4 8.2e-12 45.0 1.4 1.5 1 0 0 1 1 1 1 Berberine and berberine like Peroxidase_2 PF01328.17 EAQ86285.1 - 5.6e-46 157.4 0.0 7.2e-46 157.1 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 CorA PF01544.18 EAQ86287.1 - 4.6e-09 36.0 0.6 8.9e-09 35.1 0.5 1.5 1 1 1 2 2 2 1 CorA-like Mg2+ transporter protein CD225 PF04505.12 EAQ86287.1 - 2.7 8.2 6.5 2.5 8.3 0.1 2.6 3 0 0 3 3 3 0 Interferon-induced transmembrane protein MFS_1 PF07690.16 EAQ86289.1 - 7.1e-28 97.5 9.4 5.2e-18 65.1 7.1 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily GFA PF04828.14 EAQ86290.1 - 5.9e-12 45.8 2.8 8.9e-12 45.2 2.8 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme APH PF01636.23 EAQ86291.1 - 8.5e-13 48.8 0.1 1.4e-12 48.0 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EAQ86291.1 - 0.00055 19.6 0.0 0.00092 18.8 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF4988 PF16378.5 EAQ86293.1 - 0.021 14.5 0.0 0.051 13.2 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function FAD_binding_4 PF01565.23 EAQ86294.1 - 4.6e-11 42.6 0.3 0.00014 21.6 0.0 2.5 2 0 0 2 2 2 2 FAD binding domain BBE PF08031.12 EAQ86294.1 - 0.084 13.0 0.1 0.18 11.9 0.1 1.6 1 0 0 1 1 1 0 Berberine and berberine like Fungal_trans PF04082.18 EAQ86295.1 - 5.6e-58 196.1 0.0 7.8e-58 195.6 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain NACHT PF05729.12 EAQ86296.1 - 2.7e-07 30.7 0.0 6.4e-06 26.2 0.0 2.5 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EAQ86296.1 - 8.3e-06 26.3 0.0 2.3e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.22 EAQ86296.1 - 0.0084 15.3 0.0 0.016 14.4 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.6 EAQ86296.1 - 0.017 15.4 0.0 0.056 13.7 0.0 2.0 1 1 0 1 1 1 0 AAA domain DUF676 PF05057.14 EAQ86296.1 - 0.023 14.2 0.0 0.044 13.3 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) ATPase_2 PF01637.18 EAQ86296.1 - 0.034 14.0 0.0 0.14 12.1 0.0 1.9 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea RPN6_C_helix PF18503.1 EAQ86296.1 - 0.035 13.8 0.0 0.079 12.7 0.0 1.6 1 0 0 1 1 1 0 26S proteasome subunit RPN6 C-terminal helix domain ABC_tran PF00005.27 EAQ86296.1 - 0.037 14.5 0.0 0.071 13.6 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 EAQ86296.1 - 0.042 13.6 0.0 0.14 11.9 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain RNA_helicase PF00910.22 EAQ86296.1 - 0.084 13.3 0.1 0.2 12.1 0.1 1.6 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.6 EAQ86296.1 - 0.16 12.5 0.0 0.36 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 EAQ86296.1 - 0.16 12.4 0.0 0.82 10.1 0.0 2.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF812 PF05667.11 EAQ86297.1 - 0.0022 17.0 0.6 0.0035 16.3 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF812) zf-CCHC PF00098.23 EAQ86297.1 - 0.0026 17.8 1.7 0.0026 17.8 1.7 2.5 2 0 0 2 2 1 1 Zinc knuckle SlyX PF04102.12 EAQ86297.1 - 0.0058 17.2 5.6 0.076 13.6 5.6 2.8 1 1 0 1 1 1 1 SlyX HMMR_N PF15905.5 EAQ86297.1 - 0.059 12.8 0.6 0.15 11.5 0.4 1.6 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal USP8_interact PF08941.10 EAQ86297.1 - 0.069 13.0 0.1 0.19 11.5 0.1 1.8 1 0 0 1 1 1 0 USP8 interacting CorA PF01544.18 EAQ86297.1 - 0.073 12.4 1.5 0.16 11.2 1.5 1.5 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein PKcGMP_CC PF16808.5 EAQ86297.1 - 0.13 12.1 0.5 0.39 10.6 0.5 1.8 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase 7tm_4 PF13853.6 EAQ86297.1 - 0.18 11.5 0.0 0.3 10.8 0.0 1.2 1 0 0 1 1 1 0 Olfactory receptor DUF3584 PF12128.8 EAQ86297.1 - 0.28 8.7 4.6 0.48 7.9 4.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF2968 PF11180.8 EAQ86297.1 - 0.83 9.3 5.3 2.3 7.8 5.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) Exonuc_VII_L PF02601.15 EAQ86297.1 - 5.4 6.5 8.7 1.7 8.1 4.5 2.0 2 0 0 2 2 2 0 Exonuclease VII, large subunit RVT_1 PF00078.27 EAQ86298.1 - 5.1e-17 62.1 0.0 6e-16 58.6 0.0 2.2 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) MLTR_LBD PF17765.1 EAQ86298.1 - 0.016 15.3 0.1 0.26 11.4 0.0 2.4 2 0 0 2 2 2 0 MmyB-like transcription regulator ligand binding domain zf-RVT PF13966.6 EAQ86298.1 - 0.087 13.6 0.2 0.27 12.0 0.1 1.9 2 0 0 2 2 2 0 zinc-binding in reverse transcriptase RT_RNaseH PF17917.1 EAQ86298.1 - 0.16 12.3 0.0 0.64 10.3 0.0 2.0 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase Beta_helix PF13229.6 EAQ86299.1 - 1.3e-12 47.9 5.8 3.4e-09 36.7 0.8 2.2 1 1 1 2 2 2 2 Right handed beta helix region Chondroitinas_B PF14592.6 EAQ86299.1 - 6.6e-06 25.3 0.0 1.5e-05 24.0 0.0 1.5 2 0 0 2 2 2 1 Chondroitinase B NosD PF05048.13 EAQ86299.1 - 4e-05 23.0 3.9 0.058 12.7 0.1 2.3 2 0 0 2 2 2 2 Periplasmic copper-binding protein (NosD) DUF1281_C PF18406.1 EAQ86300.1 - 0.071 12.8 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Ferredoxin-like domain in Api92-like protein LZ3wCH PF18517.1 EAQ86300.1 - 0.13 12.3 0.1 0.22 11.7 0.1 1.3 1 0 0 1 1 1 0 Leucine zipper with capping helix domain UDP-g_GGTase PF06427.11 EAQ86300.1 - 0.15 12.2 0.0 0.2 11.8 0.0 1.2 1 0 0 1 1 1 0 UDP-glucose:Glycoprotein Glucosyltransferase AAA_16 PF13191.6 EAQ86303.1 - 1.2e-06 29.0 0.0 4e-06 27.3 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EAQ86303.1 - 0.00041 20.6 0.0 0.0014 18.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 EAQ86303.1 - 0.00059 19.8 0.0 0.0021 18.0 0.0 1.9 1 1 0 1 1 1 1 NACHT domain Abhydrolase_6 PF12697.7 EAQ86303.1 - 0.00068 20.3 0.1 0.00068 20.3 0.1 2.5 2 1 0 2 2 2 1 Alpha/beta hydrolase family AAA PF00004.29 EAQ86303.1 - 0.0019 18.6 0.0 0.01 16.3 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 EAQ86303.1 - 0.0022 18.4 0.0 0.061 13.7 0.0 2.5 2 0 0 2 2 2 1 RNA helicase DUF676 PF05057.14 EAQ86303.1 - 0.014 14.9 0.0 0.033 13.7 0.0 1.5 2 0 0 2 2 2 0 Putative serine esterase (DUF676) Mg_chelatase PF01078.21 EAQ86303.1 - 0.067 12.6 0.0 0.19 11.1 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 EAQ86303.1 - 0.068 13.3 0.1 0.27 11.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF5412 PF17428.2 EAQ86303.1 - 0.12 12.2 0.2 0.25 11.2 0.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5412) PGAP1 PF07819.13 EAQ86303.1 - 0.19 11.5 0.0 0.35 10.6 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein ATPase_2 PF01637.18 EAQ86303.1 - 0.24 11.3 0.0 0.57 10.1 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea PAS_3 PF08447.12 EAQ86304.1 - 0.016 15.5 0.6 0.055 13.8 0.2 2.0 1 1 1 2 2 2 0 PAS fold Nup54 PF13874.6 EAQ86304.1 - 0.02 15.0 1.4 0.02 15.0 1.4 2.0 1 1 0 2 2 2 0 Nucleoporin complex subunit 54 FANCI_S2 PF14676.6 EAQ86304.1 - 0.027 14.8 0.2 0.84 9.9 0.2 2.1 2 0 0 2 2 2 0 FANCI solenoid 2 CENP-H PF05837.12 EAQ86304.1 - 0.13 12.6 7.5 0.55 10.7 2.1 2.8 1 1 1 2 2 2 0 Centromere protein H (CENP-H) DUF4132 PF13569.6 EAQ86304.1 - 0.15 11.8 0.2 0.15 11.8 0.2 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4132) PI3K_P85_iSH2 PF16454.5 EAQ86304.1 - 0.45 10.1 11.0 7 6.2 0.5 3.3 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain YabA PF06156.13 EAQ86304.1 - 0.97 10.1 5.9 5 7.8 1.0 2.4 1 1 1 2 2 2 0 Initiation control protein YabA DUF4635 PF15466.6 EAQ86304.1 - 2.1 7.9 9.9 0.24 10.9 4.7 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4635) Ank_2 PF12796.7 EAQ86305.1 - 1.5e-41 140.9 0.3 8.7e-15 55.1 0.1 3.8 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 EAQ86305.1 - 4.2e-31 106.0 5.0 1.4e-06 28.5 0.0 7.0 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 EAQ86305.1 - 1.4e-30 105.0 4.2 2.2e-07 31.0 0.0 7.0 2 2 5 7 7 7 6 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAQ86305.1 - 2.5e-26 91.7 0.5 5.8e-07 29.9 0.0 4.5 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAQ86305.1 - 4.5e-22 75.8 0.3 0.0048 17.3 0.0 6.9 7 0 0 7 7 7 4 Ankyrin repeat DUF2353 PF09789.9 EAQ86306.1 - 0.00046 19.7 0.4 0.00055 19.4 0.4 1.1 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) WEMBL PF05701.11 EAQ86306.1 - 0.0029 16.4 0.3 0.0035 16.1 0.3 1.1 1 0 0 1 1 1 1 Weak chloroplast movement under blue light DUF16 PF01519.16 EAQ86306.1 - 0.031 14.7 0.6 0.042 14.3 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF16 Prominin PF05478.11 EAQ86306.1 - 0.044 11.8 0.2 0.052 11.5 0.2 1.0 1 0 0 1 1 1 0 Prominin BLOC1_2 PF10046.9 EAQ86306.1 - 0.048 14.0 0.6 0.074 13.4 0.6 1.2 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Csm1_N PF18504.1 EAQ86306.1 - 0.1 12.9 2.9 0.16 12.3 2.9 1.3 1 0 0 1 1 1 0 Csm1 N-terminal domain Spc7 PF08317.11 EAQ86306.1 - 0.17 10.8 2.3 0.2 10.5 2.3 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein NUDE_C PF04880.13 EAQ86306.1 - 0.29 11.6 3.5 0.37 11.3 3.0 1.5 1 1 0 1 1 1 0 NUDE protein, C-terminal conserved region Sporozoite_P67 PF05642.11 EAQ86307.1 - 0.76 7.8 6.2 0.84 7.6 6.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen tRNA_int_endo PF01974.17 EAQ86308.1 - 7.2e-19 67.7 0.0 1.6e-18 66.6 0.0 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.14 EAQ86308.1 - 1.6e-06 27.7 0.0 0.0076 15.9 0.0 2.3 2 0 0 2 2 2 2 tRNA intron endonuclease, N-terminal domain Cwf_Cwc_15 PF04889.12 EAQ86308.1 - 0.013 15.3 12.9 0.021 14.6 12.9 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Sigma70_ner PF04546.13 EAQ86308.1 - 0.094 12.6 11.7 0.76 9.6 7.8 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region BSP_II PF05432.11 EAQ86308.1 - 0.26 10.9 12.4 0.54 9.9 12.4 1.4 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) FAM176 PF14851.6 EAQ86308.1 - 0.5 10.0 8.9 1.2 8.8 8.9 1.6 1 0 0 1 1 1 0 FAM176 family Tim54 PF11711.8 EAQ86308.1 - 0.75 8.5 5.4 1.3 7.8 5.4 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Pox_Ag35 PF03286.14 EAQ86308.1 - 1.1 9.0 8.2 2.3 7.9 8.2 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein NOA36 PF06524.12 EAQ86308.1 - 1.2 8.4 9.0 2 7.7 9.0 1.2 1 0 0 1 1 1 0 NOA36 protein Paf1 PF03985.13 EAQ86308.1 - 1.8 7.5 9.2 2.5 7.0 9.2 1.2 1 0 0 1 1 1 0 Paf1 RXT2_N PF08595.11 EAQ86308.1 - 1.9 8.5 6.3 4 7.5 6.3 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal Astro_capsid_p PF12226.8 EAQ86308.1 - 2.1 7.4 12.6 1.8 7.6 11.0 1.6 2 0 0 2 2 2 0 Turkey astrovirus capsid protein Spore_coat_CotO PF14153.6 EAQ86308.1 - 2.2 8.2 9.8 3.8 7.4 9.8 1.4 1 0 0 1 1 1 0 Spore coat protein CotO Nop14 PF04147.12 EAQ86308.1 - 3.2 5.8 12.8 4.7 5.3 12.8 1.2 1 0 0 1 1 1 0 Nop14-like family Glyco_transf_21 PF13506.6 EAQ86309.1 - 6e-11 42.1 0.0 6.1e-08 32.3 0.0 3.7 3 1 0 3 3 3 1 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 EAQ86309.1 - 4.1e-05 23.6 0.0 0.00028 20.9 0.0 2.4 1 1 0 1 1 1 1 Glycosyltransferase like family 2 PIF1 PF05970.14 EAQ86310.1 - 2.8e-32 112.3 0.0 5.2e-28 98.2 0.0 2.4 2 1 0 2 2 2 2 PIF1-like helicase Helitron_like_N PF14214.6 EAQ86310.1 - 4.9e-24 85.6 1.8 4.6e-20 72.6 0.2 2.4 1 1 1 2 2 2 2 Helitron helicase-like domain at N-terminus AAA_30 PF13604.6 EAQ86310.1 - 2.1e-10 40.7 0.0 4.3e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAQ86310.1 - 7.2e-07 29.6 0.0 1.5e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 EAQ86310.1 - 1.6e-05 24.6 0.0 4.1e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.14 EAQ86310.1 - 0.00051 18.1 0.0 0.00092 17.3 0.0 1.3 1 0 0 1 1 1 1 Helicase Viral_helicase1 PF01443.18 EAQ86310.1 - 0.028 14.2 0.1 3 7.5 0.1 2.6 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Nif11 PF07862.11 EAQ86310.1 - 0.037 14.3 0.1 0.1 12.9 0.1 1.8 1 0 0 1 1 1 0 Nif11 domain Torsin PF06309.11 EAQ86310.1 - 0.12 12.5 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 Torsin AAA_11 PF13086.6 EAQ86310.1 - 0.14 11.9 0.0 26 4.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain SGS PF05002.15 EAQ86311.1 - 8e-30 102.8 2.1 2.1e-29 101.4 2.1 1.8 1 0 0 1 1 1 1 SGS domain CS PF04969.16 EAQ86311.1 - 1.4e-12 48.4 0.1 5e-12 46.7 0.1 1.9 1 1 0 1 1 1 1 CS domain TPR_2 PF07719.17 EAQ86311.1 - 6.6e-06 25.9 7.0 0.32 11.2 1.9 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 EAQ86311.1 - 9.7e-05 22.0 3.2 0.37 10.7 0.3 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 EAQ86311.1 - 0.00036 20.8 9.2 0.076 13.3 6.4 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 EAQ86311.1 - 0.0018 18.9 11.6 0.0028 18.3 8.9 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 EAQ86311.1 - 0.002 18.6 3.9 0.0045 17.5 3.1 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 EAQ86311.1 - 0.0067 16.6 2.8 16 6.0 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EAQ86311.1 - 0.085 13.1 4.0 0.2 11.9 2.7 2.3 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 HSP20 PF00011.21 EAQ86311.1 - 0.097 12.8 0.1 0.29 11.3 0.1 1.8 1 0 0 1 1 1 0 Hsp20/alpha crystallin family BsuPI PF12690.7 EAQ86311.1 - 0.11 12.5 0.3 0.29 11.2 0.3 1.7 1 0 0 1 1 1 0 Intracellular proteinase inhibitor TPR_7 PF13176.6 EAQ86311.1 - 0.13 12.4 5.1 3.9 7.7 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 EAQ86311.1 - 0.5 10.3 6.0 11 6.1 1.5 3.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 EAQ86311.1 - 1.4 9.1 5.6 2 8.6 3.9 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat TRAPP PF04051.16 EAQ86312.1 - 1e-40 138.8 0.0 1.2e-40 138.6 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Apc13p PF05839.11 EAQ86313.1 - 8.3e-39 131.7 0.1 1.1e-38 131.3 0.1 1.1 1 0 0 1 1 1 1 Apc13p protein Hce2 PF14856.6 EAQ86314.1 - 0.066 13.5 0.0 0.096 13.0 0.0 1.2 1 0 0 1 1 1 0 Pathogen effector; putative necrosis-inducing factor Vac7 PF12751.7 EAQ86316.1 - 0.08 12.4 0.1 2.3 7.6 0.1 2.1 2 0 0 2 2 2 0 Vacuolar segregation subunit 7 Tmemb_9 PF05434.11 EAQ86316.1 - 9.5 6.1 9.2 4 7.3 4.0 2.1 1 1 1 2 2 2 0 TMEM9 NmrA PF05368.13 EAQ86317.1 - 0.014 15.0 0.0 0.018 14.6 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family ABC_membrane PF00664.23 EAQ86320.1 - 7.6e-48 163.5 20.7 2.1e-28 99.7 7.3 2.6 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EAQ86320.1 - 1.4e-31 109.9 0.0 8.6e-19 68.4 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EAQ86320.1 - 1.8e-07 30.9 0.1 0.0016 17.9 0.0 2.9 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EAQ86320.1 - 0.00038 21.0 0.1 0.00038 21.0 0.1 1.9 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 EAQ86320.1 - 0.0033 17.3 0.1 3.2 7.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 EAQ86320.1 - 0.023 15.0 1.0 6 7.2 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EAQ86320.1 - 0.026 14.9 0.0 1.5 9.1 0.0 2.9 2 0 0 2 2 2 0 AAA ATPase domain T2SSE PF00437.20 EAQ86320.1 - 0.041 12.9 0.1 0.075 12.1 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_25 PF13481.6 EAQ86320.1 - 0.055 13.0 0.0 0.15 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 EAQ86320.1 - 0.056 13.9 0.7 0.75 10.2 0.0 2.6 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) Phage_holin_5_2 PF16079.5 EAQ86320.1 - 0.67 10.3 4.4 2.1 8.7 1.3 3.1 2 0 0 2 2 2 0 Phage holin family Hol44, in holin superfamily V COG5 PF10392.9 EAQ86321.1 - 3.9e-06 27.1 0.0 1.5e-05 25.1 0.0 1.8 1 1 0 1 1 1 1 Golgi transport complex subunit 5 BLOC1_2 PF10046.9 EAQ86321.1 - 5.4e-06 26.6 0.1 0.00036 20.8 0.0 2.8 1 1 2 3 3 3 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Baculo_PEP_C PF04513.12 EAQ86321.1 - 4.7e-05 23.4 3.1 8e-05 22.7 3.1 1.4 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 EAQ86321.1 - 0.00013 22.0 0.0 0.00031 20.8 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1664) HSBP1 PF06825.12 EAQ86321.1 - 0.00019 21.2 0.5 0.014 15.2 0.0 3.1 2 1 1 3 3 2 1 Heat shock factor binding protein 1 SlyX PF04102.12 EAQ86321.1 - 0.00032 21.3 0.1 0.024 15.2 0.0 2.2 1 1 1 2 2 2 1 SlyX CLZ PF16526.5 EAQ86321.1 - 0.00035 20.9 0.1 0.065 13.6 0.0 2.9 1 1 1 2 2 2 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Laminin_II PF06009.12 EAQ86321.1 - 0.00039 20.4 0.2 0.0026 17.8 0.1 1.9 1 1 1 2 2 2 1 Laminin Domain II FlaC_arch PF05377.11 EAQ86321.1 - 0.00049 20.4 0.5 0.0034 17.7 0.1 2.5 2 1 0 2 2 1 1 Flagella accessory protein C (FlaC) DUF3450 PF11932.8 EAQ86321.1 - 0.00071 19.0 0.0 0.00083 18.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) TolA_bind_tri PF16331.5 EAQ86321.1 - 0.0011 18.9 0.9 0.22 11.6 0.2 2.3 1 1 0 2 2 2 1 TolA binding protein trimerisation Fib_alpha PF08702.10 EAQ86321.1 - 0.0016 18.7 0.0 0.024 14.8 0.0 1.9 1 1 1 2 2 2 2 Fibrinogen alpha/beta chain family DUF4164 PF13747.6 EAQ86321.1 - 0.002 18.3 0.1 0.25 11.6 0.0 2.9 1 1 1 2 2 2 1 Domain of unknown function (DUF4164) Flagellin_C PF00700.21 EAQ86321.1 - 0.0026 18.1 0.6 0.045 14.1 0.4 2.4 1 1 1 2 2 2 1 Bacterial flagellin C-terminal helical region ADIP PF11559.8 EAQ86321.1 - 0.0028 17.7 0.0 0.0039 17.3 0.0 1.2 1 1 0 1 1 1 1 Afadin- and alpha -actinin-Binding JIP_LZII PF16471.5 EAQ86321.1 - 0.0031 17.6 0.0 0.012 15.8 0.0 1.8 1 1 1 2 2 2 1 JNK-interacting protein leucine zipper II DUF5082 PF16888.5 EAQ86321.1 - 0.0035 17.6 0.2 0.61 10.4 0.1 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF5082) DASH_Spc19 PF08287.11 EAQ86321.1 - 0.004 17.1 0.5 0.15 12.0 0.0 2.7 1 1 2 3 3 3 1 Spc19 HrpB7 PF09486.10 EAQ86321.1 - 0.0049 17.3 0.0 0.13 12.7 0.0 1.5 1 1 1 2 2 2 2 Bacterial type III secretion protein (HrpB7) DUF16 PF01519.16 EAQ86321.1 - 0.0065 16.9 0.1 0.036 14.5 0.1 2.0 1 1 0 1 1 1 1 Protein of unknown function DUF16 Trimer_CC PF08954.11 EAQ86321.1 - 0.011 15.2 2.6 0.033 13.7 0.1 2.7 2 1 1 3 3 3 0 Trimerisation motif XhlA PF10779.9 EAQ86321.1 - 0.012 15.8 0.0 0.12 12.6 0.0 2.5 1 1 1 2 2 2 0 Haemolysin XhlA MbeD_MobD PF04899.12 EAQ86321.1 - 0.013 15.6 0.2 0.66 10.1 0.0 2.5 1 1 1 2 2 2 0 MbeD/MobD like RmuC PF02646.16 EAQ86321.1 - 0.015 14.4 0.0 0.02 14.0 0.0 1.2 1 0 0 1 1 1 0 RmuC family MIS13 PF08202.11 EAQ86321.1 - 0.017 14.4 0.0 0.46 9.7 0.0 2.0 1 1 1 2 2 2 0 Mis12-Mtw1 protein family PspA_IM30 PF04012.12 EAQ86321.1 - 0.018 14.6 0.0 0.2 11.2 0.0 1.5 1 1 1 2 2 2 0 PspA/IM30 family NPV_P10 PF05531.12 EAQ86321.1 - 0.02 15.3 2.1 0.45 11.0 0.9 2.7 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Lzipper-MIP1 PF14389.6 EAQ86321.1 - 0.023 15.0 0.0 18 5.7 0.0 3.1 1 1 2 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 DUF948 PF06103.11 EAQ86321.1 - 0.033 14.4 0.3 0.28 11.5 0.3 2.2 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) ZapB PF06005.12 EAQ86321.1 - 0.035 14.6 0.0 1.2 9.6 0.0 2.4 1 1 0 1 1 1 0 Cell division protein ZapB DUF812 PF05667.11 EAQ86321.1 - 0.044 12.7 0.0 0.048 12.6 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Prominin PF05478.11 EAQ86321.1 - 0.05 11.6 0.0 0.055 11.4 0.0 1.0 1 0 0 1 1 1 0 Prominin TraF_2 PF13729.6 EAQ86321.1 - 0.056 12.8 0.5 0.33 10.3 0.2 2.1 1 1 1 2 2 2 0 F plasmid transfer operon, TraF, protein YvrJ PF12841.7 EAQ86321.1 - 0.067 12.7 0.1 48 3.6 0.0 3.5 1 1 5 6 6 6 0 YvrJ protein family Tektin PF03148.14 EAQ86321.1 - 0.072 11.8 0.0 0.12 11.1 0.0 1.3 1 1 0 1 1 1 0 Tektin family ATG16 PF08614.11 EAQ86321.1 - 0.073 13.3 0.0 0.14 12.4 0.0 1.4 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) DegS PF05384.11 EAQ86321.1 - 0.076 12.5 0.1 0.87 9.1 0.0 1.9 1 1 1 2 2 2 0 Sensor protein DegS DUF4988 PF16378.5 EAQ86321.1 - 0.078 12.6 0.1 14 5.3 0.0 2.2 1 1 0 2 2 2 0 Domain of unknown function Surfac_D-trimer PF09006.11 EAQ86321.1 - 0.084 12.8 0.1 2.9 7.9 0.0 2.9 2 1 1 3 3 3 0 Lung surfactant protein D coiled-coil trimerisation Tnp_22_trimer PF17489.2 EAQ86321.1 - 0.088 12.8 0.0 3.2 7.8 0.0 2.3 1 1 1 2 2 2 0 L1 transposable element trimerization domain TMF_DNA_bd PF12329.8 EAQ86321.1 - 0.1 12.6 0.0 0.19 11.7 0.0 1.5 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding AAA_13 PF13166.6 EAQ86321.1 - 0.11 11.1 0.0 0.12 11.0 0.0 1.0 1 0 0 1 1 1 0 AAA domain SepF PF04472.12 EAQ86321.1 - 0.11 12.7 0.1 23 5.4 0.0 2.6 1 1 2 3 3 3 0 Cell division protein SepF Hemagglutinin PF00509.18 EAQ86321.1 - 0.15 10.5 0.1 0.16 10.3 0.1 1.1 1 0 0 1 1 1 0 Haemagglutinin Jnk-SapK_ap_N PF09744.9 EAQ86321.1 - 0.15 12.3 0.0 0.31 11.2 0.0 1.5 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF4618 PF15397.6 EAQ86321.1 - 0.15 11.4 0.0 2.9 7.2 0.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) Paralemmin PF03285.15 EAQ86321.1 - 0.16 11.5 0.0 0.35 10.4 0.0 1.6 1 1 0 1 1 1 0 Paralemmin Tropomyosin_1 PF12718.7 EAQ86321.1 - 0.18 12.0 0.0 0.24 11.5 0.0 1.3 1 0 0 1 1 1 0 Tropomyosin like SecY PF00344.20 EAQ86322.1 - 6.2e-71 239.2 9.6 7.8e-71 238.8 9.6 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 EAQ86322.1 - 1e-17 63.7 0.3 3.2e-17 62.1 0.3 2.0 1 0 0 1 1 1 1 Plug domain of Sec61p IPPT PF01715.17 EAQ86323.1 - 4.6e-27 95.3 0.8 8.1e-27 94.5 0.8 1.3 1 0 0 1 1 1 1 IPP transferase zf-C2H2_jaz PF12171.8 EAQ86323.1 - 2.3e-06 27.7 0.3 5.8e-06 26.4 0.3 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EAQ86323.1 - 0.00023 21.4 0.4 0.00023 21.4 0.4 2.0 3 0 0 3 3 3 1 Zinc-finger of C2H2 type PSCyt3 PF07627.11 EAQ86323.1 - 0.11 12.7 0.3 0.3 11.4 0.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1588) Fungal_trans PF04082.18 EAQ86324.1 - 2e-13 50.0 0.0 4.5e-13 48.8 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EAQ86324.1 - 1.7e-06 28.0 6.3 3.7e-06 27.0 6.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Homeodomain PF00046.29 EAQ86325.1 - 1.3e-19 69.8 3.8 2.9e-19 68.6 3.8 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 EAQ86325.1 - 0.0029 17.5 0.5 0.0071 16.2 0.5 1.7 1 0 0 1 1 1 1 Homeobox KN domain PhoLip_ATPase_C PF16212.5 EAQ86327.1 - 6.8e-70 235.7 12.1 6.8e-70 235.7 12.1 1.9 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EAQ86327.1 - 1.4e-24 85.6 0.4 4.8e-24 83.8 0.4 2.0 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 EAQ86327.1 - 6.2e-13 49.5 0.0 4.5e-06 27.1 0.0 3.3 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EAQ86327.1 - 1.1e-12 47.8 0.0 2.8e-11 43.3 0.0 2.4 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 EAQ86327.1 - 1.2e-09 38.0 0.0 3.4e-09 36.5 0.0 1.7 1 1 0 1 1 1 1 E1-E2 ATPase MIG-14_Wnt-bd PF06664.12 EAQ86327.1 - 0.0019 17.5 0.2 0.0045 16.3 0.2 1.6 1 0 0 1 1 1 1 Wnt-binding factor required for Wnt secretion Hydrolase_3 PF08282.12 EAQ86327.1 - 0.011 15.5 0.0 0.052 13.3 0.0 1.9 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EAQ86327.1 - 0.11 12.5 0.0 0.43 10.6 0.0 1.9 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase CRAL_TRIO PF00650.20 EAQ86328.1 - 4.5e-41 140.2 0.0 8.8e-41 139.3 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EAQ86328.1 - 2.6e-16 59.6 3.0 2.6e-16 59.6 3.0 1.8 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain ADH_zinc_N_2 PF13602.6 EAQ86328.1 - 1.1e-15 58.8 0.0 2.3e-15 57.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EAQ86328.1 - 0.0025 17.8 0.0 0.0048 16.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pol_alpha_B_N PF08418.10 EAQ86329.1 - 3.2e-74 250.0 0.0 4.1e-74 249.7 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.16 EAQ86329.1 - 3.6e-40 137.6 0.0 4.8e-40 137.2 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B MFAP1 PF06991.11 EAQ86330.1 - 6.5e-77 258.2 19.4 6.5e-77 258.2 19.4 3.3 2 1 1 3 3 3 1 Microfibril-associated/Pre-mRNA processing LLC1 PF14945.6 EAQ86330.1 - 0.0089 16.6 2.0 0.059 13.9 2.0 2.4 2 0 0 2 2 2 1 Normal lung function maintenance, Low in Lung Cancer 1 protein Voldacs PF03517.13 EAQ86332.1 - 1.5e-17 64.0 0.1 3.7e-17 62.7 0.1 1.6 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling Fringe PF02434.16 EAQ86332.1 - 6.3e-06 25.8 0.0 1.6e-05 24.5 0.0 1.7 1 1 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 EAQ86332.1 - 0.084 12.7 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 Galactosyltransferase Gly_transf_sug PF04488.15 EAQ86333.1 - 2.7e-15 56.8 0.1 4.4e-15 56.1 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Glyco_hydro_61 PF03443.14 EAQ86334.1 - 5.8e-46 157.0 0.0 7e-46 156.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 NAD_binding_8 PF13450.6 EAQ86336.1 - 2.2e-11 43.8 0.2 4.5e-11 42.8 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EAQ86336.1 - 1.8e-08 33.9 0.5 3.4e-08 33.0 0.5 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 EAQ86336.1 - 2.6e-07 30.5 0.0 4.2e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 EAQ86336.1 - 2.8e-07 30.3 0.7 4.4e-07 29.6 0.7 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EAQ86336.1 - 5.9e-06 25.2 0.3 8.5e-06 24.7 0.3 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 EAQ86336.1 - 1.9e-05 25.1 0.1 4.5e-05 23.9 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EAQ86336.1 - 3.8e-05 23.1 0.3 7.6e-05 22.1 0.3 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EAQ86336.1 - 7.2e-05 22.1 0.1 0.00084 18.6 0.2 2.0 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 EAQ86336.1 - 0.00018 20.9 0.5 0.00029 20.2 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.24 EAQ86336.1 - 0.00046 19.6 0.0 0.0021 17.4 0.0 1.8 1 1 1 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 EAQ86336.1 - 0.0026 17.1 0.0 0.0043 16.4 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EAQ86336.1 - 0.007 15.5 0.5 0.01 14.9 0.5 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A K_oxygenase PF13434.6 EAQ86336.1 - 0.0078 15.4 0.1 2.8 7.0 0.3 2.2 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.14 EAQ86336.1 - 0.075 11.9 1.0 0.15 10.9 1.0 1.4 1 0 0 1 1 1 0 Tryptophan halogenase NACHT_N PF17100.5 EAQ86338.1 - 5e-15 56.0 0.0 2.9e-06 27.3 0.0 2.4 2 0 0 2 2 2 2 N-terminal domain of NWD NACHT-NTPase Ank_2 PF12796.7 EAQ86338.1 - 2.3e-06 28.1 0.8 0.15 12.7 0.3 3.3 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAQ86338.1 - 5.9e-05 23.5 2.9 0.0039 17.7 0.0 3.7 3 1 0 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 EAQ86338.1 - 0.0044 17.4 0.1 1.1 9.9 0.0 3.8 3 0 0 3 3 3 1 Ankyrin repeat NACHT PF05729.12 EAQ86338.1 - 0.0063 16.5 0.0 0.02 14.8 0.0 1.8 1 0 0 1 1 1 1 NACHT domain PMEI PF04043.15 EAQ86338.1 - 0.19 12.0 3.4 4.6 7.6 1.6 2.7 2 0 0 2 2 2 0 Plant invertase/pectin methylesterase inhibitor Ank_3 PF13606.6 EAQ86338.1 - 0.29 11.8 1.4 5.8 7.8 0.0 4.0 5 0 0 5 5 5 0 Ankyrin repeat Transferase PF02458.15 EAQ86339.1 - 6.2e-24 84.4 0.1 1.2e-10 40.6 0.0 3.4 3 1 0 3 3 3 3 Transferase family Glyco_hydro_61 PF03443.14 EAQ86340.1 - 1.1e-67 228.0 0.1 1.1e-67 228.0 0.1 1.4 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 CBM_1 PF00734.18 EAQ86340.1 - 8.9e-14 51.2 9.5 2.3e-13 49.8 9.5 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain Mito_carr PF00153.27 EAQ86341.1 - 5.9e-18 64.6 0.6 1.1e-05 25.2 0.0 4.7 4 1 0 4 4 4 4 Mitochondrial carrier protein Fer2 PF00111.27 EAQ86342.1 - 2.1e-13 50.0 0.7 3e-13 49.5 0.7 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain HAD_2 PF13419.6 EAQ86342.1 - 0.14 12.2 0.0 0.23 11.5 0.0 1.2 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Rrp15p PF07890.12 EAQ86343.1 - 5.7e-37 127.1 9.1 5.7e-37 127.1 9.1 1.8 2 0 0 2 2 2 1 Rrp15p PCSK9_C1 PF18459.1 EAQ86344.1 - 0.0088 16.2 0.0 0.0089 16.2 0.0 1.0 1 0 0 1 1 1 1 Proprotein convertase subtilisin-like/kexin type 9 C-terminal domain APH PF01636.23 EAQ86346.1 - 0.00064 19.7 0.0 0.00064 19.7 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EAQ86346.1 - 0.0042 16.7 0.0 0.0063 16.1 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF2613 PF11021.8 EAQ86348.1 - 0.0098 16.0 0.5 0.024 14.7 0.5 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2613) UPF0560 PF10577.9 EAQ86349.1 - 0.031 12.8 8.4 0.056 11.9 8.4 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 SesA PF17107.5 EAQ86350.1 - 0.00031 20.9 0.1 0.0089 16.2 0.0 2.8 2 1 0 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases VIT PF08487.10 EAQ86351.1 - 5.8e-32 110.2 0.0 1.3e-31 109.1 0.0 1.6 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.6 EAQ86351.1 - 2.8e-27 95.5 0.0 4.8e-27 94.8 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 EAQ86351.1 - 9.4e-09 35.7 0.0 1.7e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT_2 PF13757.6 EAQ86351.1 - 1.2e-08 34.7 0.0 2.4e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_CoxE PF05762.14 EAQ86351.1 - 1.1e-05 25.0 0.0 2e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein VWA_2 PF13519.6 EAQ86351.1 - 0.00054 20.6 0.0 0.0011 19.6 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain Choline_transpo PF04515.12 EAQ86352.1 - 9.4e-81 271.5 19.8 9.4e-81 271.5 19.8 2.3 2 0 0 2 2 2 1 Plasma-membrane choline transporter Pex14_N PF04695.13 EAQ86352.1 - 0.84 10.3 5.7 2.4 8.8 5.7 1.7 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Deltameth_res PF16020.5 EAQ86352.1 - 6.5 6.7 0.0 6.5 6.7 0.0 4.3 5 0 0 5 5 5 0 Deltamethrin resistance Pkinase PF00069.25 EAQ86353.1 - 1.1e-10 41.3 0.0 1.5e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ86353.1 - 0.0065 15.8 0.0 0.084 12.1 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase CobW_C PF07683.14 EAQ86353.1 - 0.41 10.6 2.8 0.16 11.9 0.3 1.6 2 0 0 2 2 2 0 Cobalamin synthesis protein cobW C-terminal domain tRNA-synt_1c PF00749.21 EAQ86354.1 - 2e-104 348.9 0.1 2.6e-104 348.5 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 EAQ86354.1 - 8.9e-40 136.4 0.0 1.4e-39 135.8 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA-synt_1e PF01406.19 EAQ86354.1 - 0.0033 16.8 0.3 0.0078 15.6 0.3 1.6 1 1 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain COG2 PF06148.11 EAQ86355.1 - 4.6e-20 72.1 0.0 6.9e-20 71.5 0.0 1.3 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.11 EAQ86355.1 - 0.0021 18.1 0.0 0.0034 17.4 0.0 1.3 1 0 0 1 1 1 1 Vps51/Vps67 Hap4_Hap_bind PF10297.9 EAQ86356.1 - 1.5e-08 34.4 6.9 1.5e-08 34.4 6.9 2.1 2 0 0 2 2 2 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_1 PF00170.21 EAQ86356.1 - 4e-06 26.8 14.1 0.0016 18.5 7.3 2.3 1 1 1 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.15 EAQ86356.1 - 0.01 15.9 9.6 1.2 9.2 4.9 2.3 2 0 0 2 2 2 0 Basic region leucine zipper DUF4482 PF14818.6 EAQ86356.1 - 0.06 14.2 2.1 0.12 13.2 2.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4482) Fmp27_WPPW PF10359.9 EAQ86356.1 - 0.091 11.6 2.0 0.13 11.1 2.0 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Herpes_UL6 PF01763.16 EAQ86356.1 - 0.24 9.9 0.0 0.31 9.5 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like TEX13 PF15186.6 EAQ86356.1 - 2.1 8.0 5.5 3.2 7.4 5.5 1.2 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family Jnk-SapK_ap_N PF09744.9 EAQ86356.1 - 3.4 7.9 8.3 5.1 7.3 8.3 1.1 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Herpes_US12 PF05363.12 EAQ86357.1 - 0.042 14.6 0.0 0.41 11.4 0.0 2.8 1 0 0 1 1 1 0 Herpesvirus US12 family tRNA_synthFbeta PF17759.1 EAQ86358.1 - 1.9e-46 158.2 0.0 2.5e-46 157.8 0.0 1.1 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 EAQ86358.1 - 2.6e-26 91.7 0.0 6.3e-25 87.2 0.0 2.7 2 1 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 EAQ86358.1 - 4.1e-21 75.4 0.1 7.8e-21 74.5 0.1 1.5 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 EAQ86358.1 - 1.5e-18 66.8 0.1 2.9e-16 59.5 0.0 2.7 3 0 0 3 3 3 2 tRNA synthetase B5 domain MFS_1 PF07690.16 EAQ86359.1 - 6.9e-33 114.0 42.5 1e-32 113.4 42.5 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 EAQ86359.1 - 8e-12 44.4 11.7 8e-12 44.4 11.7 2.1 1 1 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EAQ86359.1 - 1.3e-07 30.9 13.4 1.3e-07 30.9 13.4 3.3 3 1 0 3 3 3 1 Sugar (and other) transporter PhoLip_ATPase_C PF16212.5 EAQ86359.1 - 0.4 10.4 4.8 0.2 11.4 0.9 2.2 2 0 0 2 2 2 0 Phospholipid-translocating P-type ATPase C-terminal MFS_1 PF07690.16 EAQ86360.1 - 2.7e-29 102.2 9.2 3.9e-29 101.7 8.9 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily EutK_C PF16365.5 EAQ86360.1 - 0.093 12.8 0.3 0.46 10.6 0.1 2.1 2 0 0 2 2 2 0 Ethanolamine utilization protein EutK C-terminus Abhydrolase_1 PF00561.20 EAQ86362.1 - 8.8e-20 71.4 0.1 2.7e-17 63.3 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EAQ86362.1 - 3.2e-19 70.4 1.9 3.9e-19 70.1 1.9 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EAQ86362.1 - 3.8e-11 42.7 0.1 4.9e-11 42.3 0.1 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 EAQ86362.1 - 0.00041 20.5 0.0 0.00055 20.1 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Ser_hydrolase PF06821.13 EAQ86362.1 - 0.0026 17.6 0.3 0.012 15.5 0.0 1.9 2 0 0 2 2 2 1 Serine hydrolase DUF2974 PF11187.8 EAQ86362.1 - 0.02 14.5 0.0 0.026 14.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Chlorophyllase2 PF12740.7 EAQ86362.1 - 0.027 13.4 0.0 0.04 12.8 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme PGAP1 PF07819.13 EAQ86362.1 - 0.12 12.1 0.0 1 9.1 0.0 2.0 1 1 1 2 2 2 0 PGAP1-like protein LCAT PF02450.15 EAQ86362.1 - 0.16 11.1 0.1 0.23 10.6 0.1 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Fig1 PF12351.8 EAQ86363.1 - 1.1e-09 38.5 2.0 0.001 19.0 0.0 2.4 3 0 0 3 3 3 2 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.12 EAQ86363.1 - 0.00083 19.0 0.1 0.0012 18.6 0.1 1.2 1 0 0 1 1 1 1 SUR7/PalI family zf-H2C2_5 PF13909.6 EAQ86364.1 - 8.4e-05 22.2 0.3 0.34 10.7 0.1 2.9 2 0 0 2 2 2 2 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 EAQ86364.1 - 0.0078 17.0 7.4 0.061 14.2 0.3 3.8 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2 PF00096.26 EAQ86364.1 - 0.017 15.5 3.7 0.066 13.7 0.2 3.3 2 0 0 2 2 2 0 Zinc finger, C2H2 type Paramyxo_P_V_N PF13825.6 EAQ86365.1 - 0.096 12.1 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Paramyxovirus structural protein V/P N-terminus Phg_2220_C PF09524.10 EAQ86366.1 - 0.011 15.8 0.2 0.02 14.9 0.2 1.3 1 0 0 1 1 1 0 Conserved phage C-terminus (Phg_2220_C) Nop10p PF04135.12 EAQ86367.1 - 3.3e-20 71.9 0.1 3.6e-20 71.7 0.1 1.0 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family PIN_6 PF17146.4 EAQ86368.1 - 1.4e-31 108.8 0.1 1.4e-31 108.8 0.1 2.4 3 1 0 3 3 3 1 PIN domain of ribonuclease NOB1_Zn_bind PF08772.11 EAQ86368.1 - 2.8e-08 33.8 0.0 6.5e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like WRNPLPNID PF15017.6 EAQ86368.1 - 0.099 13.5 2.7 0.29 12.0 2.7 1.8 1 0 0 1 1 1 0 Putative WW-binding domain and destruction box HET PF06985.11 EAQ86369.1 - 2e-36 125.5 0.0 3.2e-36 124.9 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) RRN3 PF05327.11 EAQ86370.1 - 0.099 11.2 2.1 0.2 10.1 2.1 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Pox_A_type_inc PF04508.12 EAQ86370.1 - 0.21 11.5 0.5 0.84 9.6 0.5 2.1 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat RNase_J_C PF17770.1 EAQ86370.1 - 0.33 12.0 1.3 0.76 10.9 0.0 2.2 2 0 0 2 2 2 0 Ribonuclease J C-terminal domain DNA_pol_phi PF04931.13 EAQ86370.1 - 5.8 4.9 19.8 12 3.8 19.8 1.4 1 0 0 1 1 1 0 DNA polymerase phi Aa_trans PF01490.18 EAQ86373.1 - 2.1e-22 79.4 32.4 2.7e-22 79.0 32.4 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein PRT_C PF08372.10 EAQ86373.1 - 0.074 12.8 0.2 6.3 6.5 0.1 2.8 2 0 0 2 2 2 0 Plant phosphoribosyltransferase C-terminal Bys1 PF04681.12 EAQ86374.1 - 9.1e-13 48.4 0.0 1e-12 48.3 0.0 1.1 1 0 0 1 1 1 1 Blastomyces yeast-phase-specific protein Defensin_2 PF01097.18 EAQ86375.1 - 0.0011 18.8 11.2 0.0011 18.8 11.2 3.0 2 1 0 2 2 2 1 Arthropod defensin SOG2 PF10428.9 EAQ86378.1 - 0.34 10.0 8.2 0.4 9.8 8.2 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DAO PF01266.24 EAQ86380.1 - 7.6e-19 68.5 0.2 1.3e-18 67.8 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Formyl_trans_N PF00551.19 EAQ86380.1 - 5.3e-10 39.3 0.0 1.2e-09 38.1 0.0 1.6 1 0 0 1 1 1 1 Formyl transferase Pyr_redox_2 PF07992.14 EAQ86380.1 - 6.1e-05 22.4 0.1 0.49 9.6 0.0 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EAQ86380.1 - 0.00077 20.0 1.1 0.26 11.9 0.0 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EAQ86380.1 - 0.03 13.0 0.0 3.8 6.1 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_8 PF13450.6 EAQ86380.1 - 0.057 13.6 0.0 0.24 11.7 0.0 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EAQ86380.1 - 0.094 11.7 0.0 6.7 5.7 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein Mqo PF06039.15 EAQ86380.1 - 0.21 10.1 0.0 9.1 4.7 0.0 2.1 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) MFS_1 PF07690.16 EAQ86381.1 - 2.2e-28 99.2 35.5 2.2e-28 99.2 35.5 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily GATase PF00117.28 EAQ86382.1 - 1.1e-10 41.6 0.0 1.6e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Zn_clus PF00172.18 EAQ86383.1 - 0.041 14.0 15.1 0.081 13.1 15.1 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Transferase PF02458.15 EAQ86384.1 - 1.7e-08 33.6 0.0 3e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Transferase family ketoacyl-synt PF00109.26 EAQ86385.1 - 1.2e-69 234.7 1.3 2.1e-69 233.9 0.1 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 EAQ86385.1 - 2.5e-64 216.5 0.2 7.7e-64 214.9 0.2 1.9 1 0 0 1 1 1 1 KR domain Ketoacyl-synt_C PF02801.22 EAQ86385.1 - 1.3e-40 138.1 0.1 1.1e-39 135.1 0.1 2.6 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.21 EAQ86385.1 - 2.6e-35 122.5 0.6 5.1e-34 118.2 0.6 2.3 1 1 0 1 1 1 1 Acyl transferase domain ADH_zinc_N_2 PF13602.6 EAQ86385.1 - 1.8e-19 71.1 0.0 9.2e-19 68.8 0.0 2.4 2 0 0 2 2 1 1 Zinc-binding dehydrogenase KAsynt_C_assoc PF16197.5 EAQ86385.1 - 2.6e-17 63.3 0.0 7.4e-17 61.8 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N PF00107.26 EAQ86385.1 - 1e-15 57.8 5.1 2.5e-15 56.6 0.0 3.1 3 0 0 3 3 3 1 Zinc-binding dehydrogenase PS-DH PF14765.6 EAQ86385.1 - 2.6e-13 49.9 0.0 5.9e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Methyltransf_12 PF08242.12 EAQ86385.1 - 3.3e-12 47.0 0.0 1.1e-11 45.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 EAQ86385.1 - 2.6e-10 40.1 0.4 8e-10 38.5 0.0 2.0 2 0 0 2 2 1 1 short chain dehydrogenase Methyltransf_23 PF13489.6 EAQ86385.1 - 1.8e-07 31.2 0.0 4.5e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain adh_short_C2 PF13561.6 EAQ86385.1 - 5.2e-06 26.2 0.0 1.8e-05 24.4 0.0 1.9 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Methyltransf_31 PF13847.6 EAQ86385.1 - 1.4e-05 25.0 0.0 3.5e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EAQ86385.1 - 3.6e-05 24.3 0.1 0.00023 21.7 0.0 2.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAQ86385.1 - 3.9e-05 24.3 0.0 0.00025 21.7 0.0 2.5 2 0 0 2 2 1 1 Methyltransferase domain SAT PF16073.5 EAQ86385.1 - 0.0042 16.9 0.7 0.017 14.9 0.7 2.1 1 0 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis ADH_N PF08240.12 EAQ86385.1 - 0.0068 16.3 0.0 0.016 15.0 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.25 EAQ86385.1 - 0.0087 16.4 0.9 0.026 14.9 0.9 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site DUF2529 PF10740.9 EAQ86385.1 - 0.033 13.8 0.2 2 8.0 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF2529) Thiolase_N PF00108.23 EAQ86385.1 - 0.036 13.4 2.4 0.042 13.2 0.1 2.1 2 0 0 2 2 2 0 Thiolase, N-terminal domain Zeta_toxin PF06414.12 EAQ86385.1 - 0.037 13.3 0.0 0.069 12.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin NAS PF03059.16 EAQ86385.1 - 0.093 12.1 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Nicotianamine synthase protein PIF1 PF05970.14 EAQ86386.1 - 1.1e-18 67.5 0.0 1.9e-18 66.8 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 EAQ86386.1 - 2e-07 30.9 0.0 6.6e-07 29.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EAQ86386.1 - 0.00093 19.6 0.0 0.0025 18.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 EAQ86386.1 - 0.0092 15.8 0.0 0.025 14.4 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain DDE_1 PF03184.19 EAQ86387.1 - 3.5e-16 59.3 0.0 1.3e-15 57.4 0.0 2.0 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 EAQ86387.1 - 3.4e-14 52.6 0.0 6.9e-14 51.6 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.6 EAQ86387.1 - 0.00029 20.6 0.0 0.00073 19.3 0.0 1.7 1 0 0 1 1 1 1 DDE superfamily endonuclease Trp_halogenase PF04820.14 EAQ86388.1 - 1.4e-25 90.1 0.0 2.2e-11 43.3 0.0 2.8 2 1 0 2 2 2 2 Tryptophan halogenase FAD_binding_3 PF01494.19 EAQ86388.1 - 5.9e-11 42.2 0.0 2.4e-10 40.2 0.0 1.9 2 1 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 EAQ86388.1 - 3.3e-06 27.2 0.1 1.8e-05 24.9 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EAQ86388.1 - 5.3e-05 23.0 0.2 0.00012 21.8 0.2 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EAQ86388.1 - 8e-05 22.0 0.0 0.00014 21.2 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EAQ86388.1 - 8.1e-05 22.1 0.3 0.00015 21.2 0.3 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EAQ86388.1 - 0.00031 19.6 0.0 0.0005 18.9 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.22 EAQ86388.1 - 0.00047 19.4 0.1 0.00072 18.8 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 EAQ86388.1 - 0.00065 18.9 0.1 0.0012 18.0 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 EAQ86388.1 - 0.053 12.6 0.0 0.067 12.2 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox PF00070.27 EAQ86388.1 - 0.054 14.1 0.0 0.16 12.6 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 EAQ86388.1 - 0.083 13.3 0.0 0.2 12.1 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox_3 PF13738.6 EAQ86388.1 - 0.2 10.8 0.0 0.31 10.2 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Fungal_trans PF04082.18 EAQ86389.1 - 2.3e-15 56.4 0.1 4.1e-15 55.5 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EAQ86389.1 - 6.6e-09 35.8 10.6 9.1e-09 35.3 9.7 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 EAQ86390.1 - 9.9e-31 106.9 43.3 2.5e-30 105.6 43.3 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 EAQ86390.1 - 7e-12 44.6 10.4 9.6e-12 44.1 10.3 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2721 PF11026.8 EAQ86390.1 - 1.4 8.8 14.0 1.7 8.5 2.1 3.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2721) FAD_binding_3 PF01494.19 EAQ86391.1 - 5.4e-26 91.7 0.2 1.2e-25 90.5 0.2 1.5 1 1 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 EAQ86391.1 - 0.00039 19.6 0.1 0.001 18.2 0.1 1.7 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EAQ86391.1 - 0.00056 19.2 0.2 0.0071 15.6 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EAQ86391.1 - 0.001 19.3 1.9 0.0046 17.2 1.9 2.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EAQ86391.1 - 0.0012 18.5 8.6 0.0022 17.6 6.3 2.4 2 1 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EAQ86391.1 - 0.0026 18.3 1.5 0.0067 17.0 1.5 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 EAQ86391.1 - 0.0037 16.4 0.0 0.41 9.6 0.0 2.1 2 0 0 2 2 2 1 Squalene epoxidase HI0933_like PF03486.14 EAQ86391.1 - 0.019 13.7 0.8 0.027 13.2 0.8 1.2 1 0 0 1 1 1 0 HI0933-like protein Trp_halogenase PF04820.14 EAQ86391.1 - 0.038 12.8 1.1 1.3 7.8 0.2 2.2 2 0 0 2 2 2 0 Tryptophan halogenase Pyr_redox_3 PF13738.6 EAQ86391.1 - 0.039 13.2 0.0 0.11 11.8 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EAQ86391.1 - 0.054 12.8 2.6 0.1 12.0 2.6 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase 3HCDH_N PF02737.18 EAQ86391.1 - 0.063 13.2 0.1 0.12 12.3 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.22 EAQ86391.1 - 0.14 11.2 1.7 0.26 10.3 1.7 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_9 PF13454.6 EAQ86391.1 - 0.3 11.1 1.6 13 5.8 1.3 2.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding ketoacyl-synt PF00109.26 EAQ86392.1 - 3.7e-69 233.1 0.8 8.6e-69 231.9 0.8 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EAQ86392.1 - 2.2e-32 111.5 0.0 4.9e-32 110.4 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.21 EAQ86392.1 - 1.7e-25 90.2 0.3 1.3e-23 84.1 0.2 2.2 2 0 0 2 2 2 1 Acyl transferase domain SAT PF16073.5 EAQ86392.1 - 7.4e-12 45.5 3.8 1.1e-07 31.9 0.1 3.1 3 0 0 3 3 3 2 Starter unit:ACP transacylase in aflatoxin biosynthesis Thiolase_N PF00108.23 EAQ86392.1 - 9.9e-05 21.8 0.1 0.00018 20.9 0.1 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain KAsynt_C_assoc PF16197.5 EAQ86392.1 - 0.0027 18.1 0.0 0.0081 16.6 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ACP_syn_III PF08545.10 EAQ86392.1 - 0.29 11.0 2.2 0.58 10.1 0.2 2.4 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III HTH_51 PF18558.1 EAQ86393.1 - 2.4e-23 81.8 0.0 4.5e-23 80.9 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain PS-DH PF14765.6 EAQ86393.1 - 2.4e-14 53.3 0.5 4e-14 52.6 0.5 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Methyltransf_12 PF08242.12 EAQ86393.1 - 5.7e-11 43.0 0.0 1.5e-10 41.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 EAQ86393.1 - 2.7e-10 40.4 0.1 5.8e-10 39.4 0.1 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_23 PF13489.6 EAQ86393.1 - 3.5e-10 40.0 0.0 7.8e-10 38.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAQ86393.1 - 4.1e-09 37.0 0.0 1.3e-08 35.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EAQ86393.1 - 3.7e-06 27.5 0.0 9.6e-06 26.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAQ86393.1 - 6.7e-06 26.0 0.0 1.3e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain SGT1 PF07093.11 EAQ86393.1 - 3.7 5.9 5.1 6 5.2 5.1 1.2 1 0 0 1 1 1 0 SGT1 protein NAD_binding_4 PF07993.12 EAQ86394.1 - 6.4e-11 41.9 0.0 9.3e-11 41.4 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein CBM-like PF14683.6 EAQ86395.1 - 3.3e-29 101.9 0.2 6.7e-29 100.9 0.2 1.6 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.6 EAQ86395.1 - 4.8e-24 84.0 1.3 1.8e-23 82.1 1.3 2.1 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.6 EAQ86395.1 - 0.066 13.5 0.5 0.066 13.5 0.5 3.2 4 0 0 4 4 4 0 Carboxypeptidase regulatory-like domain FAD_binding_4 PF01565.23 EAQ86396.1 - 1.7e-23 82.9 0.9 3.4e-23 81.9 0.9 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EAQ86396.1 - 4.8e-09 36.2 0.0 1.5e-08 34.6 0.0 1.9 1 1 0 1 1 1 1 Berberine and berberine like Phage_gp49_66 PF13876.6 EAQ86396.1 - 0.15 12.4 0.0 31 5.0 0.0 2.4 2 0 0 2 2 2 0 Phage protein (N4 Gp49/phage Sf6 gene 66) family adh_short PF00106.25 EAQ86397.1 - 3.8e-08 33.0 0.0 7.8e-08 32.0 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 EAQ86397.1 - 3.6e-05 23.7 0.0 6.2e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 EAQ86397.1 - 0.0065 16.0 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Pox_E8 PF03394.13 EAQ86398.1 - 0.17 11.4 1.8 0.95 9.0 0.4 2.2 2 0 0 2 2 2 0 Poxvirus E8 protein DUF1688 PF07958.11 EAQ86400.1 - 1.6e-178 593.8 0.0 1.8e-178 593.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) PLU-1 PF08429.11 EAQ86402.1 - 4.5e-115 384.4 13.2 3.5e-112 374.9 11.1 2.2 2 0 0 2 2 2 2 PLU-1-like protein JmjC PF02373.22 EAQ86402.1 - 9.6e-27 93.7 0.0 2.6e-26 92.3 0.0 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase ARID PF01388.21 EAQ86402.1 - 5.2e-22 78.3 0.1 1.8e-21 76.6 0.1 2.0 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain PHD PF00628.29 EAQ86402.1 - 1.8e-17 63.0 28.6 8.3e-10 38.4 5.8 3.8 3 0 0 3 3 3 2 PHD-finger JmjN PF02375.17 EAQ86402.1 - 3.3e-15 55.7 3.0 8e-15 54.5 3.0 1.7 1 0 0 1 1 1 1 jmjN domain zf-C5HC2 PF02928.16 EAQ86402.1 - 7.7e-12 45.4 4.7 2.6e-11 43.8 4.7 2.0 1 0 0 1 1 1 1 C5HC2 zinc finger PHD_4 PF16866.5 EAQ86402.1 - 0.1 12.7 21.6 1 9.5 6.2 3.9 3 0 0 3 3 3 0 PHD-finger Chloroplast_duf PF14476.6 EAQ86402.1 - 0.11 11.5 2.1 0.26 10.3 0.1 2.1 2 0 0 2 2 2 0 Petal formation-expressed zf-PHD-like PF15446.6 EAQ86402.1 - 0.33 10.6 9.7 1.5 8.4 2.0 2.7 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain C1_1 PF00130.22 EAQ86402.1 - 0.5 10.3 18.4 0.19 11.6 0.8 3.1 3 0 0 3 3 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Rubredoxin PF00301.20 EAQ86402.1 - 0.77 9.8 7.9 0.67 10.0 1.8 3.2 2 0 0 2 2 2 0 Rubredoxin zf-RING_2 PF13639.6 EAQ86402.1 - 3.3 8.1 21.7 4.8 7.6 6.8 2.9 2 0 0 2 2 2 0 Ring finger domain Zf_RING PF16744.5 EAQ86402.1 - 7.2 6.8 17.2 5.1 7.3 5.1 3.4 2 2 0 2 2 2 0 KIAA1045 RING finger GIY-YIG PF01541.24 EAQ86404.1 - 7e-13 48.7 0.0 1.3e-12 47.9 0.0 1.4 1 0 0 1 1 1 1 GIY-YIG catalytic domain FANCL_C PF11793.8 EAQ86404.1 - 0.00054 20.1 2.9 0.001 19.2 2.9 1.4 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING_2 PF13639.6 EAQ86404.1 - 0.0013 19.0 4.4 0.0028 18.0 4.4 1.6 1 0 0 1 1 1 1 Ring finger domain zf-HC5HC2H PF13771.6 EAQ86404.1 - 0.022 15.0 3.7 0.048 13.9 3.7 1.5 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 EAQ86404.1 - 0.033 14.4 4.2 0.071 13.3 4.2 1.5 1 1 0 1 1 1 0 PHD-zinc-finger like domain PHD PF00628.29 EAQ86404.1 - 0.049 13.5 5.5 0.082 12.8 5.5 1.4 1 0 0 1 1 1 0 PHD-finger PHD_Oberon PF07227.11 EAQ86404.1 - 0.096 12.6 1.2 0.15 12.0 1.2 1.2 1 0 0 1 1 1 0 PHD - plant homeodomain finger protein T5orf172 PF10544.9 EAQ86404.1 - 0.12 12.9 0.0 0.31 11.6 0.0 1.7 1 0 0 1 1 1 0 T5orf172 domain zf-C2HC PF01530.18 EAQ86404.1 - 0.15 12.3 3.0 0.33 11.2 3.0 1.6 1 0 0 1 1 1 0 Zinc finger, C2HC type YdjO PF14169.6 EAQ86404.1 - 0.34 10.7 0.0 0.34 10.7 0.0 3.0 2 1 0 2 2 2 0 Cold-inducible protein YdjO zf-RING_5 PF14634.6 EAQ86404.1 - 0.44 10.6 5.6 1.1 9.3 5.6 1.7 1 1 0 1 1 1 0 zinc-RING finger domain Prok-RING_1 PF14446.6 EAQ86404.1 - 0.58 10.1 6.5 0.76 9.7 2.6 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-C3HC4_2 PF13923.6 EAQ86404.1 - 2.2 8.2 4.8 5.2 7.0 1.4 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EAQ86404.1 - 5.3 7.0 8.1 15 5.6 0.2 2.3 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF3449 PF11931.8 EAQ86405.1 - 2.3e-72 242.6 0.9 6.8e-72 241.1 0.2 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3449) SF3A3 PF16837.5 EAQ86405.1 - 3.4e-25 88.3 0.1 6.8e-25 87.4 0.1 1.5 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 SF3a60_bindingd PF12108.8 EAQ86405.1 - 1.4e-12 47.3 0.1 3.2e-12 46.1 0.1 1.7 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-C2H2_jaz PF12171.8 EAQ86405.1 - 4.2e-10 39.6 3.4 8.3e-08 32.3 0.7 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EAQ86405.1 - 1.7e-08 34.6 1.0 2.1e-06 27.9 0.5 2.4 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 EAQ86405.1 - 0.0015 18.8 0.0 0.27 11.6 0.1 2.7 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 EAQ86405.1 - 0.066 14.1 1.1 15 6.7 0.1 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger PRP9_N PF16958.5 EAQ86405.1 - 0.072 13.1 11.0 0.12 12.3 0.3 3.1 2 1 1 3 3 3 0 Pre-mRNA-splicing factor PRP9 N-terminus zf-C4H2 PF10146.9 EAQ86405.1 - 0.23 11.8 0.1 0.23 11.8 0.1 1.8 2 0 0 2 2 2 0 Zinc finger-containing protein zf-U1 PF06220.12 EAQ86405.1 - 0.29 10.9 2.8 0.3 10.9 0.3 2.1 2 0 0 2 2 2 0 U1 zinc finger zf-DBF PF07535.12 EAQ86405.1 - 2.8 8.1 5.6 0.69 10.1 0.1 2.7 2 1 0 2 2 2 0 DBF zinc finger DEAD PF00270.29 EAQ86406.1 - 6e-43 146.6 0.2 9.9e-43 145.9 0.2 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EAQ86406.1 - 2.6e-33 114.7 0.0 9.4e-33 112.9 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 EAQ86406.1 - 0.00042 20.1 0.1 0.00063 19.5 0.1 1.3 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 EAQ86406.1 - 0.0011 19.0 0.0 0.0023 18.0 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 EAQ86406.1 - 0.0017 18.7 0.2 0.011 16.0 0.1 2.1 2 0 0 2 2 2 1 AAA domain DUF5393 PF17371.2 EAQ86406.1 - 0.051 11.7 0.1 0.08 11.1 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5393) Flavi_DEAD PF07652.14 EAQ86406.1 - 0.056 13.4 0.2 0.19 11.7 0.0 2.0 2 1 0 2 2 2 0 Flavivirus DEAD domain TniB PF05621.11 EAQ86406.1 - 0.064 12.7 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein Helicase_RecD PF05127.14 EAQ86406.1 - 0.071 13.0 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Helicase AAA_22 PF13401.6 EAQ86406.1 - 0.14 12.4 0.9 0.65 10.3 0.9 2.0 1 1 0 1 1 1 0 AAA domain Pro-kuma_activ PF09286.11 EAQ86408.1 - 5.6e-33 114.2 0.0 1.1e-32 113.3 0.0 1.5 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 EAQ86408.1 - 0.00074 18.9 0.2 0.0041 16.4 0.2 1.9 1 1 0 1 1 1 1 Subtilase family MFS_1 PF07690.16 EAQ86409.1 - 5.5e-29 101.2 47.2 1.6e-28 99.7 28.1 2.2 1 1 2 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EAQ86409.1 - 9.7e-28 97.2 23.2 2.3e-21 76.2 9.8 2.4 1 1 0 2 2 2 2 Sugar (and other) transporter LacY_symp PF01306.19 EAQ86409.1 - 0.011 14.5 16.2 0.0035 16.2 12.7 1.8 2 1 0 2 2 2 0 LacY proton/sugar symporter Peptidase_A8 PF01252.18 EAQ86409.1 - 9.6 6.4 9.3 0.55 10.5 1.8 2.6 2 1 0 2 2 2 0 Signal peptidase (SPase) II Sdh_cyt PF01127.22 EAQ86411.1 - 4.4e-18 65.5 3.7 6.2e-18 65.0 3.7 1.2 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit TAF6_C PF07571.13 EAQ86412.1 - 9.5e-26 90.0 0.0 2.1e-25 88.9 0.0 1.6 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain TAF PF02969.17 EAQ86412.1 - 8.2e-20 70.8 0.0 1.7e-19 69.7 0.0 1.6 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) AA_permease_2 PF13520.6 EAQ86414.1 - 2e-50 171.9 18.6 1.1e-49 169.4 15.8 2.0 1 1 1 2 2 2 2 Amino acid permease AA_permease PF00324.21 EAQ86414.1 - 2.1e-13 49.7 17.4 3e-13 49.2 17.4 1.2 1 0 0 1 1 1 1 Amino acid permease DUF2619 PF10942.8 EAQ86414.1 - 0.048 13.7 0.3 0.048 13.7 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2619) Aa_trans PF01490.18 EAQ86414.1 - 0.18 10.5 11.1 2.7 6.6 11.1 2.5 1 1 0 1 1 1 0 Transmembrane amino acid transporter protein Glyco_hydro_61 PF03443.14 EAQ86415.1 - 4.7e-55 186.7 0.4 5.8e-55 186.4 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Melibiase_2 PF16499.5 EAQ86416.1 - 3.8e-37 128.0 6.1 9.5e-37 126.7 6.1 1.7 1 1 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 EAQ86416.1 - 7.9e-13 48.3 2.0 4.9e-11 42.6 0.0 3.2 3 0 0 3 3 3 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 EAQ86416.1 - 0.00076 18.5 0.0 0.0012 17.9 0.0 1.2 1 0 0 1 1 1 1 Melibiase Lipase_GDSL_2 PF13472.6 EAQ86418.1 - 4.9e-19 69.4 0.1 6.6e-19 69.0 0.1 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EAQ86418.1 - 3.4e-11 43.5 0.0 4.7e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 EAQ86418.1 - 0.00038 20.6 0.0 0.00053 20.2 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family OSK PF17182.4 EAQ86418.1 - 0.022 14.0 0.0 0.029 13.6 0.0 1.1 1 0 0 1 1 1 0 OSK domain EcKinase PF02958.20 EAQ86419.1 - 1.6e-15 57.2 0.0 3.2e-14 52.9 0.0 2.1 1 1 0 1 1 1 1 Ecdysteroid kinase APH PF01636.23 EAQ86419.1 - 1.5e-08 34.9 0.6 2.9e-08 33.9 0.6 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 EAQ86419.1 - 2.4e-05 23.4 0.0 3.1e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) RNA_pol_Rpb1_2 PF00623.20 EAQ86420.1 - 0.16 12.2 0.1 1.2 9.3 0.0 2.0 2 0 0 2 2 2 0 RNA polymerase Rpb1, domain 2 Cellulase PF00150.18 EAQ86422.1 - 5.7e-47 160.5 0.1 7.7e-47 160.0 0.1 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_61 PF03443.14 EAQ86423.1 - 2.1e-60 204.2 0.0 2.7e-60 203.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 NPCBM_assoc PF10633.9 EAQ86423.1 - 0.075 13.3 0.0 0.66 10.3 0.0 2.3 2 0 0 2 2 2 0 NPCBM-associated, NEW3 domain of alpha-galactosidase SpdB PF05122.13 EAQ86423.1 - 1.2 9.3 4.1 1.6 8.9 0.2 2.4 2 0 0 2 2 2 0 Mobile element transfer protein PNTB PF02233.16 EAQ86424.1 - 6.2e-174 579.2 27.8 6.2e-174 579.2 27.8 2.0 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.21 EAQ86424.1 - 5.4e-62 208.9 5.7 5.8e-60 202.2 0.8 3.0 3 1 0 3 3 3 1 Alanine dehydrogenase/PNT, C-terminal domain PNTB_4TM PF12769.7 EAQ86424.1 - 1.3e-30 105.6 2.6 1.3e-30 105.6 2.6 5.9 4 2 2 6 6 6 1 4TM region of pyridine nucleotide transhydrogenase, mitoch AlaDh_PNT_N PF05222.15 EAQ86424.1 - 1.6e-09 38.2 0.2 4.3e-09 36.8 0.2 1.8 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain Pyr_redox_2 PF07992.14 EAQ86424.1 - 0.0063 15.8 0.2 0.016 14.4 0.2 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 EAQ86424.1 - 0.0071 15.7 0.2 1.8 7.9 0.1 2.5 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TPP_enzyme_M PF00205.22 EAQ86424.1 - 0.13 12.0 0.3 0.74 9.6 0.3 2.4 1 1 0 1 1 1 0 Thiamine pyrophosphate enzyme, central domain Git3 PF11710.8 EAQ86424.1 - 0.18 11.6 1.0 0.28 10.9 0.1 1.8 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 PRIMA1 PF16101.5 EAQ86424.1 - 0.43 10.6 1.9 1.3 9.1 1.9 1.8 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 PLDc_2 PF13091.6 EAQ86425.1 - 1.6e-08 34.5 0.0 3.8e-06 26.8 0.0 2.5 2 1 0 2 2 2 2 PLD-like domain PLDc PF00614.22 EAQ86425.1 - 3.7e-06 26.9 1.4 0.0044 17.1 0.1 3.1 2 1 0 2 2 2 2 Phospholipase D Active site motif CENP-K PF11802.8 EAQ86425.1 - 0.1 12.2 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Centromere-associated protein K DUF3348 PF11828.8 EAQ86427.1 - 0.12 12.0 0.1 0.17 11.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3348) p450 PF00067.22 EAQ86428.1 - 4.9e-48 164.0 0.0 1.7e-45 155.7 0.0 2.6 2 1 0 2 2 2 2 Cytochrome P450 Lipase_GDSL_2 PF13472.6 EAQ86429.1 - 6.3e-21 75.6 2.0 1.1e-20 74.7 2.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EAQ86429.1 - 6.5e-07 29.5 0.1 1.7e-06 28.1 0.1 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Glyco_hydro_32C PF08244.12 EAQ86431.1 - 5.5e-34 117.4 0.1 1.2e-33 116.4 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Glyco_hydro_32N PF00251.20 EAQ86431.1 - 5.5e-34 118.1 1.8 6.2e-14 52.3 0.1 3.2 3 0 0 3 3 3 3 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32N PF00251.20 EAQ86432.1 - 3.9e-23 82.5 7.1 4.5e-23 82.3 7.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain FAD_binding_3 PF01494.19 EAQ86433.1 - 7.6e-16 58.3 0.0 6.2e-08 32.3 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 EAQ86433.1 - 6.8e-05 22.2 0.2 0.0047 16.2 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EAQ86433.1 - 0.00047 19.8 0.1 0.0081 15.8 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EAQ86433.1 - 0.0034 16.5 0.0 0.0059 15.7 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain MucBP_2 PF17965.1 EAQ86433.1 - 0.01 16.4 0.1 0.027 15.0 0.1 1.7 2 0 0 2 2 2 1 Mucin binding domain NAD_binding_8 PF13450.6 EAQ86433.1 - 0.024 14.9 0.0 0.06 13.6 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HALZ PF02183.18 EAQ86433.1 - 0.094 12.9 0.3 1.9 8.8 0.1 2.5 2 0 0 2 2 2 0 Homeobox associated leucine zipper Pyr_redox PF00070.27 EAQ86433.1 - 0.14 12.8 0.1 0.32 11.6 0.1 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EAQ86433.1 - 0.23 10.6 0.2 1.7 7.9 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase MULE PF10551.9 EAQ86434.1 - 9.4e-20 70.8 0.1 2.8e-19 69.3 0.0 1.8 2 0 0 2 2 2 1 MULE transposase domain IBR PF01485.21 EAQ86435.1 - 5.3e-11 42.6 49.4 1.2e-07 31.8 3.2 4.6 4 1 0 4 4 4 3 IBR domain, a half RING-finger domain Methyltransf_PK PF05891.12 EAQ86436.1 - 8.3e-72 241.2 0.0 9.4e-72 241.1 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 EAQ86436.1 - 0.00044 20.9 0.0 0.00072 20.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EAQ86436.1 - 0.025 15.3 0.0 0.037 14.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.18 EAQ86436.1 - 0.062 12.6 0.0 0.1 11.9 0.0 1.4 1 1 0 1 1 1 0 O-methyltransferase domain Succ_CoA_lig PF13607.6 EAQ86436.1 - 0.12 12.1 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Succinyl-CoA ligase like flavodoxin domain Ank_4 PF13637.6 EAQ86437.1 - 1.4e-16 60.6 0.3 3.2e-08 33.9 0.1 2.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAQ86437.1 - 4.8e-13 49.5 0.8 2.1e-05 25.0 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAQ86437.1 - 7.8e-12 45.2 2.5 1.5e-07 31.5 0.4 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAQ86437.1 - 2e-08 33.8 0.4 0.0012 19.2 0.0 3.0 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 EAQ86437.1 - 8.2e-08 32.4 5.0 0.00014 22.2 0.1 2.8 3 0 0 3 3 3 2 Ankyrin repeat Ketoacyl-synt_2 PF13723.6 EAQ86437.1 - 0.009 15.7 0.3 0.018 14.7 0.0 1.6 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain EPSP_synthase PF00275.20 EAQ86437.1 - 0.11 11.1 0.0 0.16 10.6 0.0 1.1 1 0 0 1 1 1 0 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) TPR_7 PF13176.6 EAQ86438.1 - 0.0042 17.0 0.5 0.062 13.4 0.1 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 EAQ86438.1 - 0.0069 16.5 0.3 0.073 13.3 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 EAQ86438.1 - 0.0079 16.5 1.3 0.17 12.2 0.5 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 EAQ86438.1 - 0.021 15.4 0.3 0.17 12.6 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 EAQ86438.1 - 0.042 13.7 0.2 1.3 8.9 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 EAQ86438.1 - 0.3 11.3 1.2 2.3 8.5 0.3 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat SQHop_cyclase_C PF13243.6 EAQ86439.1 - 5.5e-46 157.1 2.3 3.5e-44 151.2 1.0 2.8 2 1 1 3 3 3 1 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 EAQ86439.1 - 3.8e-38 131.3 12.0 2.1e-35 122.2 2.3 3.9 4 1 1 5 5 5 3 Squalene-hopene cyclase N-terminal domain Prenyltrans PF00432.21 EAQ86439.1 - 2.6e-27 94.2 11.1 3.2e-10 39.6 0.2 5.1 5 0 0 5 5 5 3 Prenyltransferase and squalene oxidase repeat TED_complement PF07678.14 EAQ86439.1 - 1.6e-05 24.1 0.0 0.013 14.5 0.0 3.3 3 1 1 4 4 4 2 A-macroglobulin TED domain Pec_lyase PF09492.10 EAQ86439.1 - 0.00035 20.0 0.1 0.33 10.2 0.0 4.1 4 1 0 5 5 5 1 Pectic acid lyase TIP120 PF08623.10 EAQ86440.1 - 2.8e-71 238.7 5.9 2.2e-68 229.3 0.3 4.3 4 1 0 4 4 4 2 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.6 EAQ86440.1 - 2.2e-13 50.4 16.0 0.023 15.1 0.0 8.7 8 2 1 9 9 9 5 HEAT repeats HEAT PF02985.22 EAQ86440.1 - 4.9e-11 41.9 23.1 1 9.8 0.0 11.6 12 0 0 12 12 12 3 HEAT repeat Vac14_Fab1_bd PF12755.7 EAQ86440.1 - 7.8e-06 26.4 2.0 0.33 11.6 0.0 6.1 7 2 2 9 9 5 1 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 EAQ86440.1 - 0.00047 18.9 10.8 0.52 8.8 1.0 6.0 6 2 0 6 6 6 2 Adaptin N terminal region RTP1_C1 PF10363.9 EAQ86440.1 - 0.00095 19.3 8.0 0.2 11.8 0.1 5.3 6 0 0 6 6 6 1 Required for nuclear transport of RNA pol II C-terminus 1 Cnd1 PF12717.7 EAQ86440.1 - 0.0012 18.9 12.4 0.3 11.1 0.1 5.6 4 2 2 6 6 6 2 non-SMC mitotic condensation complex subunit 1 VHS PF00790.19 EAQ86440.1 - 0.0013 18.6 0.0 0.55 10.1 0.1 2.8 2 0 0 2 2 2 1 VHS domain HEAT_EZ PF13513.6 EAQ86440.1 - 0.0019 18.6 24.8 35 5.0 0.0 12.5 14 2 1 15 15 14 0 HEAT-like repeat RNA_pol_3_Rpc31 PF11705.8 EAQ86440.1 - 0.0037 17.5 0.7 0.0064 16.8 0.7 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 RasGEF_N_2 PF14663.6 EAQ86440.1 - 0.022 15.1 1.5 1.4 9.3 0.0 3.9 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain V-ATPase_H_C PF11698.8 EAQ86440.1 - 0.033 14.3 1.9 0.51 10.5 0.0 3.9 4 0 0 4 4 3 0 V-ATPase subunit H Cnd3 PF12719.7 EAQ86440.1 - 0.054 12.7 0.4 2.5 7.2 0.0 3.5 4 0 0 4 4 4 0 Nuclear condensing complex subunits, C-term domain DUF3361 PF11841.8 EAQ86440.1 - 0.094 12.7 5.7 1.4 8.8 0.1 4.0 3 1 1 4 4 4 0 Domain of unknown function (DUF3361) Voldacs PF03517.13 EAQ86440.1 - 0.15 12.2 1.0 0.35 11.0 1.0 1.6 1 0 0 1 1 1 0 Regulator of volume decrease after cellular swelling MMS19_C PF12460.8 EAQ86440.1 - 2.1 7.3 9.3 17 4.3 0.1 5.2 6 0 0 6 6 6 0 RNAPII transcription regulator C-terminal RIX1 PF08167.12 EAQ86440.1 - 4.4 7.0 7.8 1.4 8.6 0.0 4.0 6 0 0 6 6 6 0 rRNA processing/ribosome biogenesis DUF885 PF05960.11 EAQ86441.1 - 0.001 18.8 1.3 0.0012 18.6 1.3 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF885) Apolipoprotein PF01442.18 EAQ86441.1 - 0.044 13.7 6.7 0.21 11.4 6.7 1.9 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF2937 PF11157.8 EAQ86441.1 - 0.083 12.6 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) Macoilin PF09726.9 EAQ86441.1 - 0.21 10.1 6.4 0.23 10.0 6.4 1.1 1 0 0 1 1 1 0 Macoilin family DUF4588 PF15251.6 EAQ86441.1 - 1.4 8.7 12.0 2.1 8.1 10.9 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4588) FSA_C PF10479.9 EAQ86441.1 - 1.9 6.5 11.3 2.3 6.2 11.3 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus DUF3138 PF11336.8 EAQ86441.1 - 4.6 5.7 8.0 6.3 5.3 8.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Presenilin PF01080.17 EAQ86441.1 - 7.8 5.1 7.3 9.7 4.8 7.3 1.1 1 0 0 1 1 1 0 Presenilin Porphobil_deam PF01379.20 EAQ86442.1 - 2.4e-74 249.3 0.0 3.5e-74 248.7 0.0 1.2 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 EAQ86442.1 - 3e-20 72.4 2.0 5.3e-20 71.6 2.0 1.4 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain HrcA PF01628.21 EAQ86442.1 - 0.11 12.4 0.1 0.42 10.5 0.0 1.8 2 0 0 2 2 2 0 HrcA protein C terminal domain GCV_H PF01597.19 EAQ86443.1 - 9.6e-15 54.6 0.4 3.8e-11 42.9 0.1 2.1 1 1 1 2 2 2 2 Glycine cleavage H-protein Ras PF00071.22 EAQ86444.1 - 9.6e-12 44.8 0.8 2.2e-10 40.4 0.1 2.0 2 0 0 2 2 2 1 Ras family Roc PF08477.13 EAQ86444.1 - 6.6e-09 36.0 0.1 1.1e-08 35.3 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase DLIC PF05783.11 EAQ86444.1 - 0.031 13.1 0.2 0.3 9.9 0.0 2.0 1 1 1 2 2 2 0 Dynein light intermediate chain (DLIC) AAA_7 PF12775.7 EAQ86444.1 - 0.16 11.4 0.3 0.71 9.4 0.0 1.8 1 1 1 2 2 2 0 P-loop containing dynein motor region BRCT PF00533.26 EAQ86445.1 - 4.7e-06 26.9 0.0 9.1e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 EAQ86445.1 - 5.5e-05 23.0 0.0 0.00012 21.9 0.0 1.5 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_2 PF16589.5 EAQ86445.1 - 7.2e-05 23.1 0.0 0.00018 21.9 0.0 1.7 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT_3 PF18428.1 EAQ86445.1 - 0.088 12.9 0.0 11 6.2 0.0 2.5 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain DUF4048 PF13257.6 EAQ86446.1 - 1.3e-13 51.4 12.9 1.3e-13 51.4 12.9 4.0 3 2 1 4 4 4 2 Domain of unknown function (DUF4048) Bap31_Bap29_C PF18035.1 EAQ86446.1 - 0.1 12.6 0.3 0.21 11.6 0.3 1.5 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain DUF4407 PF14362.6 EAQ86446.1 - 0.23 10.8 1.6 0.73 9.1 1.8 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) ATP-synt_ab PF00006.25 EAQ86447.1 - 1.9e-73 246.6 0.0 2.6e-73 246.2 0.0 1.1 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain BET PF17035.5 EAQ86447.1 - 0.16 12.2 0.2 0.48 10.6 0.1 1.8 2 0 0 2 2 2 0 Bromodomain extra-terminal - transcription regulation N-SET PF11764.8 EAQ86448.1 - 1.8e-54 184.5 0.4 1.8e-54 184.5 0.4 3.1 3 0 0 3 3 3 1 COMPASS (Complex proteins associated with Set1p) component N SET_assoc PF11767.8 EAQ86448.1 - 1.1e-27 95.4 2.2 1.8e-27 94.7 0.8 2.2 3 0 0 3 3 3 1 Histone lysine methyltransferase SET associated SET PF00856.28 EAQ86448.1 - 1e-20 74.8 0.1 1e-20 74.8 0.1 3.3 2 2 0 2 2 2 1 SET domain Securin PF04856.13 EAQ86449.1 - 0.047 13.6 2.6 0.13 12.3 2.0 2.1 1 1 0 1 1 1 0 Securin sister-chromatid separation inhibitor Tropomyosin_1 PF12718.7 EAQ86450.1 - 1.7e-54 183.9 33.7 2e-54 183.7 33.7 1.0 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.20 EAQ86450.1 - 9.3e-09 35.0 33.4 2.2e-05 23.9 7.6 3.0 1 1 2 3 3 3 3 Tropomyosin CENP-F_leu_zip PF10473.9 EAQ86450.1 - 3.6e-06 27.0 32.2 0.0032 17.5 3.1 2.6 1 1 1 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATG16 PF08614.11 EAQ86450.1 - 0.00061 20.1 32.8 0.64 10.2 21.7 2.2 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) HMMR_C PF15908.5 EAQ86450.1 - 0.00084 19.6 19.0 0.0015 18.8 3.3 2.9 1 1 2 3 3 3 1 Hyaluronan mediated motility receptor C-terminal DUF5082 PF16888.5 EAQ86450.1 - 0.0012 19.1 18.9 0.88 9.9 6.2 3.2 2 1 1 3 3 3 3 Domain of unknown function (DUF5082) DUF724 PF05266.14 EAQ86450.1 - 0.0012 18.7 25.3 0.049 13.5 7.2 2.0 1 1 0 2 2 2 2 Protein of unknown function (DUF724) HMMR_N PF15905.5 EAQ86450.1 - 0.0014 18.2 28.4 0.0018 17.8 28.4 1.1 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal Uso1_p115_C PF04871.13 EAQ86450.1 - 0.0018 18.6 35.8 0.026 14.9 13.0 2.0 1 1 1 2 2 2 2 Uso1 / p115 like vesicle tethering protein, C terminal region Spc7 PF08317.11 EAQ86450.1 - 0.0023 16.9 33.0 0.014 14.3 12.1 2.0 1 1 1 2 2 2 2 Spc7 kinetochore protein GAS PF13851.6 EAQ86450.1 - 0.0074 15.7 31.6 0.056 12.8 11.9 2.6 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding Laminin_II PF06009.12 EAQ86450.1 - 0.01 15.9 2.9 0.01 15.9 2.9 2.1 1 1 1 2 2 2 0 Laminin Domain II Fez1 PF06818.15 EAQ86450.1 - 0.01 16.3 26.8 0.014 15.8 26.8 1.2 1 0 0 1 1 1 0 Fez1 DUF4200 PF13863.6 EAQ86450.1 - 0.014 15.8 32.6 0.18 12.2 12.9 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) Taxilin PF09728.9 EAQ86450.1 - 0.017 14.3 29.3 0.022 14.0 14.7 2.0 1 1 1 2 2 2 0 Myosin-like coiled-coil protein T3SSipB PF16535.5 EAQ86450.1 - 0.018 15.6 20.1 0.69 10.4 8.8 3.0 1 1 1 2 2 2 0 Type III cell invasion protein SipB KLRAQ PF10205.9 EAQ86450.1 - 0.026 14.7 22.3 0.25 11.6 8.4 3.1 1 1 2 3 3 3 0 Predicted coiled-coil domain-containing protein ERM PF00769.19 EAQ86450.1 - 0.028 14.2 37.4 0.058 13.2 15.6 2.0 1 1 1 2 2 2 0 Ezrin/radixin/moesin family KELK PF15796.5 EAQ86450.1 - 0.028 14.9 33.3 0.1 13.1 3.7 4.1 1 1 3 4 4 4 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase NPV_P10 PF05531.12 EAQ86450.1 - 0.049 14.1 11.4 4.1 7.9 4.6 3.3 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein Lebercilin PF15619.6 EAQ86450.1 - 0.079 12.6 32.1 0.59 9.8 16.9 2.3 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease TMF_TATA_bd PF12325.8 EAQ86450.1 - 0.098 12.9 26.5 0.38 11.0 16.4 2.6 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding APG6_N PF17675.1 EAQ86450.1 - 0.1 13.1 38.7 1.3 9.5 24.0 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region BRE1 PF08647.11 EAQ86450.1 - 0.1 12.7 31.0 0.14 12.2 4.8 2.4 1 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase IFT46_B_C PF12317.8 EAQ86450.1 - 0.11 12.2 9.4 0.17 11.6 8.3 1.7 1 1 1 2 2 2 0 Intraflagellar transport complex B protein 46 C terminal DUF1664 PF07889.12 EAQ86450.1 - 0.11 12.5 15.4 0.13 12.4 1.9 2.9 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) ADIP PF11559.8 EAQ86450.1 - 0.15 12.2 30.1 0.16 12.0 10.3 3.1 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding bZIP_1 PF00170.21 EAQ86450.1 - 0.16 12.1 27.2 0.11 12.6 4.3 4.7 2 2 2 4 4 4 0 bZIP transcription factor CENP-H PF05837.12 EAQ86450.1 - 0.16 12.4 26.8 3.6 8.0 0.2 3.1 1 1 2 3 3 3 0 Centromere protein H (CENP-H) DUF4686 PF15742.5 EAQ86450.1 - 0.17 11.0 32.2 0.83 8.7 32.3 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4686) Jnk-SapK_ap_N PF09744.9 EAQ86450.1 - 0.21 11.8 33.3 0.049 13.9 20.2 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 CASP_C PF08172.12 EAQ86450.1 - 0.21 10.9 20.6 0.3 10.4 2.8 2.1 2 0 0 2 2 2 0 CASP C terminal DUF3450 PF11932.8 EAQ86450.1 - 0.23 10.7 29.4 1.9 7.8 8.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Syntaxin-6_N PF09177.11 EAQ86450.1 - 0.24 12.0 19.9 5.9 7.5 9.1 2.9 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Rab5-bind PF09311.11 EAQ86450.1 - 0.25 10.7 26.7 0.16 11.4 9.9 2.1 1 1 1 2 2 2 0 Rabaptin-like protein EzrA PF06160.12 EAQ86450.1 - 0.25 9.5 22.7 0.56 8.3 19.5 1.8 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA YscO PF07321.12 EAQ86450.1 - 0.31 11.0 29.5 2.2 8.2 10.6 3.0 1 1 2 3 3 3 0 Type III secretion protein YscO UPF0242 PF06785.11 EAQ86450.1 - 0.37 10.9 31.6 0.46 10.6 12.1 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus XhlA PF10779.9 EAQ86450.1 - 0.43 10.8 25.3 0.91 9.8 2.5 4.1 1 1 4 5 5 5 0 Haemolysin XhlA Cortex-I_coil PF09304.10 EAQ86450.1 - 0.47 10.7 21.1 7.9 6.7 4.9 3.3 1 1 2 3 3 3 0 Cortexillin I, coiled coil LPD39 PF18858.1 EAQ86450.1 - 0.47 10.5 18.1 28 4.7 18.1 2.0 1 1 0 1 1 1 0 Large polyvalent protein associated domain 39 TPR_MLP1_2 PF07926.12 EAQ86450.1 - 0.68 10.0 37.5 0.78 9.8 13.8 2.7 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein HOOK PF05622.12 EAQ86450.1 - 0.71 8.0 28.2 1.3 7.1 28.2 1.4 1 1 0 1 1 1 0 HOOK protein PspA_IM30 PF04012.12 EAQ86450.1 - 0.73 9.4 30.7 0.98 9.0 7.2 2.2 1 1 1 2 2 2 0 PspA/IM30 family HAP1_N PF04849.13 EAQ86450.1 - 0.83 8.8 28.9 3.6 6.7 28.9 2.4 1 1 0 1 1 1 0 HAP1 N-terminal conserved region TRAF_BIRC3_bd PF16673.5 EAQ86450.1 - 0.88 9.4 19.6 6 6.7 0.5 3.9 1 1 4 5 5 5 0 TNF receptor-associated factor BIRC3 binding domain ZapB PF06005.12 EAQ86450.1 - 0.88 10.1 38.8 11 6.5 0.3 4.0 1 1 2 3 3 3 0 Cell division protein ZapB DUF4472 PF14739.6 EAQ86450.1 - 0.9 10.3 28.3 1.2 9.9 10.0 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF4472) SOGA PF11365.8 EAQ86450.1 - 0.92 10.7 23.2 3.9 8.7 7.8 3.4 1 1 2 3 3 3 0 Protein SOGA AAA_11 PF13086.6 EAQ86450.1 - 0.93 9.2 15.2 1.2 8.9 15.2 1.2 1 0 0 1 1 1 0 AAA domain DUF2203 PF09969.9 EAQ86450.1 - 0.98 10.2 20.1 0.59 10.9 4.7 2.2 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) FlaC_arch PF05377.11 EAQ86450.1 - 1.1 9.8 18.4 4.4 7.8 0.4 4.1 2 1 2 4 4 4 0 Flagella accessory protein C (FlaC) Seryl_tRNA_N PF02403.22 EAQ86450.1 - 1.2 9.4 27.4 5.6 7.2 0.5 3.1 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain CALCOCO1 PF07888.11 EAQ86450.1 - 1.4 7.7 31.8 4.4 6.1 18.4 2.0 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF4201 PF13870.6 EAQ86450.1 - 1.5 8.5 23.7 1.7e+02 1.8 23.7 2.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) Fmp27_WPPW PF10359.9 EAQ86450.1 - 1.6 7.5 24.4 0.035 13.0 8.3 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain CLZ PF16526.5 EAQ86450.1 - 1.7 9.1 25.5 30 5.1 7.6 3.5 1 1 2 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels MPS2 PF17060.5 EAQ86450.1 - 1.8 7.7 13.9 2.5 7.3 13.9 1.2 1 0 0 1 1 1 0 Monopolar spindle protein 2 Shugoshin_N PF07558.11 EAQ86450.1 - 1.9 8.4 9.0 3.3 7.6 0.2 3.8 4 1 0 4 4 3 0 Shugoshin N-terminal coiled-coil region DUF4407 PF14362.6 EAQ86450.1 - 2 7.7 23.3 3.9 6.8 23.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) BLOC1_2 PF10046.9 EAQ86450.1 - 2.1 8.7 21.8 6.5 7.1 1.9 3.5 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF812 PF05667.11 EAQ86450.1 - 2.3 7.0 29.2 3.4 6.5 29.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) TMF_DNA_bd PF12329.8 EAQ86450.1 - 2.5 8.2 34.2 1.3 9.1 15.3 3.1 1 1 3 4 4 4 0 TATA element modulatory factor 1 DNA binding DUF16 PF01519.16 EAQ86450.1 - 2.6 8.6 24.1 3.9 8.0 7.3 3.1 1 1 2 3 3 3 0 Protein of unknown function DUF16 SHE3 PF17078.5 EAQ86450.1 - 3.1 7.5 23.8 2.6 7.7 3.1 2.5 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 DUF4482 PF14818.6 EAQ86450.1 - 3.3 8.6 24.0 0.42 11.5 2.7 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF4482) KASH_CCD PF14662.6 EAQ86450.1 - 3.7 7.3 32.0 1.2 8.9 18.1 2.5 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH DUF3584 PF12128.8 EAQ86450.1 - 3.7 4.9 27.3 4.8 4.6 27.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) PI3K_P85_iSH2 PF16454.5 EAQ86450.1 - 4 7.0 25.9 22 4.6 2.1 2.1 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain FUSC PF04632.12 EAQ86450.1 - 4.5 5.7 11.2 5.1 5.5 11.2 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family GIT_CC PF16559.5 EAQ86450.1 - 5.4 6.9 18.9 0.25 11.2 2.9 4.0 2 1 2 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor FapA PF03961.13 EAQ86450.1 - 6.3 5.3 24.6 1.1 7.8 6.8 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A Ax_dynein_light PF10211.9 EAQ86450.1 - 7.8 6.4 31.6 2.9 7.8 4.4 3.7 1 1 2 3 3 3 0 Axonemal dynein light chain YabA PF06156.13 EAQ86450.1 - 7.9 7.2 23.3 2.7e+02 2.2 8.0 2.9 1 1 1 2 2 2 0 Initiation control protein YabA DUF730 PF05325.11 EAQ86450.1 - 8 6.5 13.7 5.4 7.1 2.3 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF730) Nop25 PF09805.9 EAQ86451.1 - 1.7e-42 145.1 13.1 1.7e-42 145.1 13.1 2.1 2 0 0 2 2 2 1 Nucleolar protein 12 (25kDa) ATP-synt_S1 PF05827.12 EAQ86452.1 - 0.00031 20.6 0.1 0.00053 19.8 0.1 1.3 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) Pro_isomerase PF00160.21 EAQ86453.1 - 2.9e-49 167.4 0.4 3.5e-49 167.1 0.4 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Syntaxin-6_N PF09177.11 EAQ86454.1 - 2.7e-25 88.8 0.2 3e-24 85.5 0.0 2.1 2 0 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.19 EAQ86454.1 - 4.1e-06 26.7 0.3 1.9e-05 24.5 0.1 2.2 2 0 0 2 2 2 1 SNARE domain TBCA PF02970.16 EAQ86454.1 - 0.0069 16.7 2.4 0.013 15.8 0.9 2.2 2 0 0 2 2 2 1 Tubulin binding cofactor A DUF3584 PF12128.8 EAQ86454.1 - 0.018 12.6 1.2 0.036 11.6 0.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Use1 PF09753.9 EAQ86454.1 - 0.047 13.4 0.0 0.059 13.1 0.0 1.3 1 1 0 1 1 1 0 Membrane fusion protein Use1 Pox_EPC_I2-L1 PF12575.8 EAQ86454.1 - 0.071 13.3 1.7 32 4.8 0.0 3.2 3 0 0 3 3 3 0 Poxvirus entry protein complex L1 and I2 APG17 PF04108.12 EAQ86454.1 - 0.1 11.7 2.2 3.8 6.5 0.4 2.3 2 1 0 2 2 2 0 Autophagy protein Apg17 Spc24 PF08286.11 EAQ86454.1 - 0.15 12.3 1.5 3.6 7.9 0.0 2.5 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 DUF1664 PF07889.12 EAQ86454.1 - 0.16 12.0 1.8 4.4 7.4 0.5 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF4164 PF13747.6 EAQ86454.1 - 0.25 11.7 4.1 1 9.7 1.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) COG2 PF06148.11 EAQ86454.1 - 0.32 11.1 3.2 4.9 7.2 0.0 2.8 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 PilJ PF13675.6 EAQ86454.1 - 0.36 10.9 3.2 1.5 8.9 0.1 2.6 2 1 1 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term GLE1 PF07817.13 EAQ86455.1 - 6e-50 169.8 0.0 9.4e-49 165.9 0.0 2.1 1 1 0 1 1 1 1 GLE1-like protein PSD5 PF07637.11 EAQ86455.1 - 0.0039 17.5 3.8 2.9 8.3 4.6 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF1595) RNB PF00773.19 EAQ86457.1 - 1.2e-79 268.0 0.0 2.2e-79 267.2 0.0 1.4 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 EAQ86457.1 - 3.6e-27 94.2 0.1 1.6e-26 92.1 0.0 2.3 2 0 0 2 2 2 1 Dis3-like cold-shock domain 2 (CSD2) Dis3l2_C_term PF17877.1 EAQ86457.1 - 5.3e-25 87.6 0.0 2.4e-24 85.5 0.0 2.2 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal CSD2 PF17876.1 EAQ86457.1 - 3.3e-07 30.4 0.0 0.0025 17.9 0.0 2.7 2 0 0 2 2 2 2 Cold shock domain TFIIA PF03153.13 EAQ86457.1 - 0.0045 17.0 7.7 0.0045 17.0 7.7 2.5 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit Rrp44_CSD1 PF17216.3 EAQ86457.1 - 0.012 15.3 1.4 0.024 14.3 0.0 2.0 2 0 0 2 2 2 0 Rrp44-like cold shock domain GRP PF07172.11 EAQ86457.1 - 0.55 11.0 6.9 0.2 12.4 0.8 2.6 2 0 0 2 2 2 0 Glycine rich protein family DUF2722 PF10846.8 EAQ86457.1 - 0.81 8.6 12.6 0.36 9.7 2.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Ferritin_2 PF13668.6 EAQ86459.1 - 1.2e-38 132.4 1.3 2.3e-38 131.5 1.3 1.4 1 0 0 1 1 1 1 Ferritin-like domain Molydop_binding PF01568.21 EAQ86459.1 - 0.066 13.3 0.4 0.15 12.1 0.0 1.7 2 0 0 2 2 2 0 Molydopterin dinucleotide binding domain ELFV_dehydrog PF00208.21 EAQ86460.1 - 1.2e-81 274.1 4.0 1.4e-81 273.8 4.0 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 EAQ86460.1 - 3e-49 166.2 0.0 5.5e-49 165.4 0.0 1.4 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain NAD_binding_7 PF13241.6 EAQ86460.1 - 0.054 13.9 0.2 0.16 12.4 0.1 1.8 2 0 0 2 2 2 0 Putative NAD(P)-binding GMC_oxred_C PF05199.13 EAQ86461.1 - 8.2e-11 42.6 0.1 1.4e-09 38.6 0.1 2.8 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_N PF00732.19 EAQ86461.1 - 0.00025 20.5 0.0 0.00047 19.6 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Hydrolase_4 PF12146.8 EAQ86461.1 - 0.053 12.8 0.0 3.7 6.7 0.0 2.3 2 0 0 2 2 2 0 Serine aminopeptidase, S33 SOG2 PF10428.9 EAQ86461.1 - 2.8 7.1 7.6 86 2.1 8.8 2.3 2 0 0 2 2 2 0 RAM signalling pathway protein DNA_pol_B PF00136.21 EAQ86462.1 - 3.7e-148 494.1 1.7 5e-148 493.6 1.7 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 EAQ86462.1 - 5.7e-80 269.0 2.5 6.4e-80 268.8 0.5 2.2 3 0 0 3 3 3 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 EAQ86462.1 - 5.2e-15 55.7 5.2 1.4e-14 54.3 5.2 1.8 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.13 EAQ86462.1 - 0.00054 19.0 0.4 0.0049 15.8 0.0 2.2 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral DNA_pol_B_exo2 PF10108.9 EAQ86462.1 - 0.0021 17.8 0.1 0.0041 16.8 0.1 1.4 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 EAQ86462.1 - 0.0028 17.6 0.2 0.017 15.1 0.2 2.4 1 1 0 1 1 1 1 RNase_H superfamily DUF2614 PF11023.8 EAQ86462.1 - 0.038 14.1 0.1 0.083 13.0 0.1 1.5 1 0 0 1 1 1 0 Zinc-ribbon containing domain C1_1 PF00130.22 EAQ86462.1 - 3.7 7.5 9.4 1.2 9.1 0.7 2.5 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF410 PF04190.13 EAQ86464.1 - 2.7e-92 309.2 0.0 3.8e-92 308.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF410) UIM PF02809.20 EAQ86466.1 - 0.15 12.0 1.2 0.49 10.4 1.2 1.9 1 0 0 1 1 1 0 Ubiquitin interaction motif AIM3 PF17096.5 EAQ86466.1 - 0.47 11.4 2.1 1.4 9.9 2.1 1.8 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 UQ_con PF00179.26 EAQ86467.1 - 3.7e-35 120.6 0.0 4.6e-35 120.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Pkinase PF00069.25 EAQ86468.1 - 5.5e-68 229.2 0.0 3.5e-30 105.3 0.0 4.1 3 1 0 3 3 3 3 Protein kinase domain HGTP_anticodon2 PF12745.7 EAQ86468.1 - 7.5e-52 176.4 4.7 1.5e-51 175.4 0.0 2.3 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs Pkinase_Tyr PF07714.17 EAQ86468.1 - 4.1e-42 144.2 0.0 4.6e-17 62.2 0.0 3.3 3 0 0 3 3 3 3 Protein tyrosine kinase tRNA-synt_His PF13393.6 EAQ86468.1 - 4.1e-15 55.8 0.0 1.1e-14 54.4 0.0 1.7 1 0 0 1 1 1 1 Histidyl-tRNA synthetase RWD PF05773.22 EAQ86468.1 - 3.4e-11 43.5 0.2 9.4e-11 42.0 0.2 1.8 1 0 0 1 1 1 1 RWD domain Kinase-like PF14531.6 EAQ86468.1 - 7.7e-06 25.4 0.0 9.2e-05 21.9 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EAQ86468.1 - 4.9e-05 22.3 4.4 0.11 11.3 0.0 3.1 3 0 0 3 3 3 2 Fungal protein kinase APH PF01636.23 EAQ86468.1 - 0.00011 22.3 1.3 0.47 10.3 0.0 3.2 3 0 0 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.14 EAQ86468.1 - 0.00079 18.8 0.0 0.17 11.2 0.0 2.4 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EAQ86468.1 - 0.0038 16.9 0.2 0.42 10.2 0.0 3.2 3 0 0 3 3 3 1 Kinetochore Sim4 complex subunit FTA2 Cut12 PF11500.8 EAQ86469.1 - 5.6e-43 146.4 11.0 5.6e-43 146.4 11.0 3.7 2 1 2 4 4 4 1 Spindle pole body formation-associated protein UPF0242 PF06785.11 EAQ86469.1 - 9.6e-05 22.6 21.6 9.6e-05 22.6 21.6 2.5 2 1 1 3 3 3 1 Uncharacterised protein family (UPF0242) N-terminus UreF PF01730.16 EAQ86470.1 - 7.2e-22 78.4 0.4 1.3e-21 77.6 0.1 1.6 2 0 0 2 2 2 1 UreF DUF429 PF04250.13 EAQ86470.1 - 0.026 14.3 0.2 0.043 13.6 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF429) MSP1_C PF07462.11 EAQ86470.1 - 0.69 8.5 1.5 0.97 8.0 1.5 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Herpes_pp85 PF04637.12 EAQ86470.1 - 0.82 8.0 2.6 1.1 7.6 2.6 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Torus PF16131.5 EAQ86471.1 - 3.8e-45 153.0 0.4 6.2e-45 152.4 0.0 1.5 2 0 0 2 2 2 1 Torus domain RRM_1 PF00076.22 EAQ86471.1 - 9.9e-08 31.7 0.0 1.8e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 EAQ86471.1 - 0.00013 21.9 0.7 0.00013 21.9 0.7 1.8 2 0 0 2 2 2 1 Zinc finger domain Nup35_RRM_2 PF14605.6 EAQ86471.1 - 0.011 15.7 0.0 0.021 14.8 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif zf-CCCH PF00642.24 EAQ86471.1 - 0.065 13.2 0.7 0.13 12.3 0.7 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) MMR_HSR1_Xtn PF16897.5 EAQ86472.1 - 2.8e-35 120.5 1.6 7.5e-35 119.1 0.5 2.0 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 EAQ86472.1 - 4e-21 75.2 0.0 9.4e-21 74.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.21 EAQ86472.1 - 1.1e-20 73.4 0.1 1.9e-20 72.7 0.1 1.4 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 EAQ86472.1 - 5.7e-13 48.7 0.0 9e-13 48.0 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EAQ86472.1 - 7.7e-05 22.8 0.2 0.054 13.6 0.0 2.5 1 1 1 2 2 2 2 Dynamin family MeaB PF03308.16 EAQ86472.1 - 0.083 11.9 0.1 0.17 10.9 0.1 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB MCM PF00493.23 EAQ86472.1 - 0.098 11.7 0.0 0.23 10.6 0.0 1.5 2 0 0 2 2 2 0 MCM P-loop domain Spo12 PF05032.12 EAQ86473.1 - 2.3e-15 56.2 0.5 5.4e-15 55.0 0.5 1.7 1 0 0 1 1 1 1 Spo12 family Acyl-CoA_dh_1 PF00441.24 EAQ86474.1 - 4.4e-29 101.6 0.5 7.6e-29 100.8 0.5 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EAQ86474.1 - 3.1e-20 72.2 0.0 5.7e-20 71.3 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 EAQ86474.1 - 1.8e-14 54.4 0.0 3.9e-14 53.3 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 EAQ86474.1 - 4.2e-12 46.5 0.9 8.2e-12 45.6 0.4 1.7 1 1 1 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain UCH_1 PF13423.6 EAQ86476.1 - 7.5e-33 114.5 0.0 6.7e-32 111.3 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Porin_3 PF01459.22 EAQ86477.1 - 3.1e-68 230.2 0.7 1.4e-50 172.2 0.2 2.0 1 1 1 2 2 2 2 Eukaryotic porin 6PF2K PF01591.18 EAQ86478.1 - 9.3e-51 172.3 0.7 3.5e-50 170.4 0.7 1.8 1 1 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 EAQ86478.1 - 9.1e-21 74.4 0.2 3.4e-20 72.5 0.2 1.9 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) ZnuA PF01297.17 EAQ86478.1 - 0.04 13.3 0.0 0.069 12.5 0.0 1.4 1 0 0 1 1 1 0 Zinc-uptake complex component A periplasmic PH PF00169.29 EAQ86479.1 - 0.02 15.4 0.0 0.042 14.4 0.0 1.5 1 0 0 1 1 1 0 PH domain DUF1501 PF07394.12 EAQ86479.1 - 0.035 13.2 0.5 0.058 12.4 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) polyprenyl_synt PF00348.17 EAQ86480.1 - 3.2e-79 265.6 0.0 4e-79 265.3 0.0 1.0 1 0 0 1 1 1 1 Polyprenyl synthetase ANAPC8 PF04049.13 EAQ86481.1 - 1.2e-52 177.7 0.2 5e-52 175.7 0.0 2.1 3 0 0 3 3 3 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_1 PF00515.28 EAQ86481.1 - 9.7e-20 69.5 9.5 0.0004 20.1 0.0 8.0 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_8 PF13181.6 EAQ86481.1 - 2.8e-19 67.6 18.4 6.5e-05 22.8 0.0 8.2 9 0 0 9 9 8 5 Tetratricopeptide repeat TPR_2 PF07719.17 EAQ86481.1 - 5.2e-14 51.2 24.5 0.23 11.7 0.0 9.6 9 1 1 10 10 10 4 Tetratricopeptide repeat TPR_14 PF13428.6 EAQ86481.1 - 5.3e-10 39.3 21.7 0.0054 17.5 0.1 8.3 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_11 PF13414.6 EAQ86481.1 - 6.3e-08 32.2 0.2 2.3e-06 27.2 0.1 2.9 1 1 1 2 2 2 1 TPR repeat TPR_16 PF13432.6 EAQ86481.1 - 6.1e-07 30.0 10.2 5.2e-06 27.0 0.7 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 EAQ86481.1 - 1.3e-06 28.6 20.3 0.64 10.4 0.1 7.5 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 EAQ86481.1 - 9.4e-06 25.3 10.1 0.08 13.0 0.0 5.4 5 0 0 5 5 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EAQ86481.1 - 0.00013 22.2 7.4 0.084 13.1 0.6 4.6 3 1 1 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 EAQ86481.1 - 0.00035 20.8 0.1 9.7 6.8 0.0 5.6 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_9 PF13371.6 EAQ86481.1 - 0.0014 18.7 14.0 0.37 11.0 0.1 5.2 4 1 1 5 5 5 2 Tetratricopeptide repeat DUF3856 PF12968.7 EAQ86481.1 - 0.022 14.8 1.3 0.91 9.6 0.2 2.8 1 1 1 2 2 2 0 Domain of Unknown Function (DUF3856) TPR_10 PF13374.6 EAQ86481.1 - 0.023 14.6 9.7 8.6 6.4 0.1 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat ChAPs PF09295.10 EAQ86481.1 - 0.039 13.0 0.0 1.8 7.5 0.0 2.2 2 0 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) Say1_Mug180 PF10340.9 EAQ86481.1 - 0.099 11.5 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Steryl acetyl hydrolase TPR_19 PF14559.6 EAQ86481.1 - 0.27 11.8 17.8 6.3 7.4 0.0 7.0 7 1 1 9 9 8 0 Tetratricopeptide repeat TPR_6 PF13174.6 EAQ86481.1 - 6.2 7.7 21.2 3.6 8.4 0.3 7.8 9 1 0 9 9 9 0 Tetratricopeptide repeat Vps54 PF07928.12 EAQ86482.1 - 3.8e-28 98.6 0.2 1.4e-27 96.8 0.0 2.1 2 0 0 2 2 2 1 Vps54-like protein Vps54_N PF10475.9 EAQ86482.1 - 1.9e-07 30.7 0.6 5.3e-07 29.2 0.6 1.7 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex DUF2451 PF10474.9 EAQ86482.1 - 2.4e-06 27.5 0.0 6.6e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) Sec8_exocyst PF04048.14 EAQ86482.1 - 0.051 13.4 0.9 0.68 9.8 0.4 2.6 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain COG2 PF06148.11 EAQ86482.1 - 0.058 13.5 1.8 0.24 11.5 1.8 2.0 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 MCM PF00493.23 EAQ86483.1 - 9.3e-106 351.9 0.1 4.4e-105 349.7 0.1 1.9 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 EAQ86483.1 - 1.3e-35 122.0 0.2 2.3e-35 121.2 0.2 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EAQ86483.1 - 1.6e-28 99.0 2.0 3.7e-28 97.8 2.0 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EAQ86483.1 - 7.6e-14 52.2 0.1 1.9e-13 50.9 0.1 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 EAQ86483.1 - 3.2e-07 29.9 0.0 0.0002 20.8 0.0 2.3 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EAQ86483.1 - 5.8e-05 23.1 0.0 0.00013 22.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EAQ86483.1 - 0.00024 21.0 0.1 0.0012 18.7 0.0 2.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EAQ86483.1 - 0.062 13.0 0.0 1.2 8.8 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain Mg_chelatase_C PF13335.6 EAQ86483.1 - 0.12 13.0 2.6 0.31 11.7 1.6 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI C-terminal AMP-binding PF00501.28 EAQ86484.1 - 1.3e-16 60.2 0.0 2e-07 30.0 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme NPCC PF08058.11 EAQ86485.1 - 2.4e-27 95.6 0.0 3.7e-27 94.9 0.0 1.3 1 0 0 1 1 1 1 Nuclear pore complex component EHN PF06441.12 EAQ86486.1 - 4.2e-21 75.3 0.1 6.3e-21 74.8 0.1 1.3 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Hid1 PF12722.7 EAQ86487.1 - 0 1030.2 0.0 0 1030.1 0.0 1.0 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 EAQ86487.1 - 1.7e-96 324.1 0.0 2.1e-96 323.8 0.0 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Ank_4 PF13637.6 EAQ86487.1 - 0.041 14.5 0.3 7.7 7.2 0.0 3.2 3 0 0 3 3 3 0 Ankyrin repeats (many copies) SPC22 PF04573.12 EAQ86488.1 - 1.8e-32 112.2 0.3 2.9e-31 108.3 0.3 2.0 1 1 0 1 1 1 1 Signal peptidase subunit XRN_M PF17846.1 EAQ86489.1 - 1.1e-100 337.6 4.0 1.9e-100 336.9 4.0 1.3 1 0 0 1 1 1 1 Xrn1 helical domain XRN_N PF03159.18 EAQ86489.1 - 1.4e-98 329.2 0.0 2.3e-98 328.5 0.0 1.4 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN1_D1 PF18332.1 EAQ86489.1 - 2.4e-77 259.1 0.0 4e-77 258.3 0.0 1.4 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D1 domain XRN1_D2_D3 PF18334.1 EAQ86489.1 - 5.6e-33 113.0 0.0 1.4e-32 111.7 0.0 1.8 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D2/D3 domain SH3_12 PF18129.1 EAQ86489.1 - 2.3e-23 82.0 0.3 4.7e-23 81.1 0.3 1.6 1 0 0 1 1 1 1 Xrn1 SH3-like domain Xrn1_D3 PF18194.1 EAQ86489.1 - 6.8e-05 22.9 0.0 0.00021 21.3 0.0 1.8 1 0 0 1 1 1 1 Exoribonuclease 1 Domain-3 R3H PF01424.22 EAQ86489.1 - 0.02 14.9 0.0 0.048 13.7 0.0 1.6 1 0 0 1 1 1 0 R3H domain Thioredoxin_14 PF18402.1 EAQ86489.1 - 0.17 11.8 0.7 6 6.7 0.3 2.3 2 0 0 2 2 2 0 Thioredoxin-like domain DUF1345 PF07077.11 EAQ86489.1 - 0.25 11.1 0.1 0.43 10.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1345) WD40 PF00400.32 EAQ86490.1 - 2.2e-19 69.4 6.9 6e-06 26.9 0.2 5.7 6 0 0 6 6 6 3 WD domain, G-beta repeat CAF1C_H4-bd PF12265.8 EAQ86490.1 - 1.4e-15 57.3 0.1 4.2e-15 55.7 0.1 1.8 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex ANAPC4_WD40 PF12894.7 EAQ86490.1 - 7.1e-05 23.0 0.0 0.012 15.9 0.0 2.8 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain SGL PF08450.12 EAQ86490.1 - 0.0065 16.1 0.0 0.013 15.1 0.0 1.5 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region PAS_7 PF12860.7 EAQ86491.1 - 0.13 12.4 1.9 0.36 11.0 0.7 2.2 2 0 0 2 2 2 0 PAS fold zf-RanBP PF00641.18 EAQ86492.1 - 2.1e-17 62.1 13.1 7e-10 38.1 1.5 2.3 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others RRM_1 PF00076.22 EAQ86492.1 - 3.1e-08 33.3 0.0 6.4e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNase_T PF00929.24 EAQ86492.1 - 1.8e-06 28.6 0.0 3e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Exonuclease Pmp3 PF01679.17 EAQ86493.1 - 0.00052 20.2 5.4 0.00073 19.7 5.4 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator DUF4401 PF14351.6 EAQ86493.1 - 0.0087 15.4 0.0 0.0098 15.2 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4401) Pkinase PF00069.25 EAQ86495.1 - 4.2e-71 239.4 0.0 5.6e-71 239.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ86495.1 - 1.4e-33 116.3 0.0 3.1e-33 115.1 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAQ86495.1 - 0.071 12.4 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 EAQ86495.1 - 0.12 11.7 0.1 0.23 10.8 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EAQ86495.1 - 0.17 10.8 0.3 0.33 9.9 0.1 1.4 2 0 0 2 2 2 0 Haspin like kinase domain Pkinase_fungal PF17667.1 EAQ86495.1 - 0.36 9.6 0.0 0.36 9.6 0.0 2.2 2 0 0 2 2 2 0 Fungal protein kinase Glycogen_syn PF05693.13 EAQ86497.1 - 0 1178.0 0.0 0 1177.8 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glyco_transf_5 PF08323.11 EAQ86497.1 - 2e-05 24.4 0.1 4.2e-05 23.4 0.1 1.5 1 0 0 1 1 1 1 Starch synthase catalytic domain Glyco_trans_1_4 PF13692.6 EAQ86497.1 - 3.4e-05 24.3 0.0 0.027 14.9 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 EAQ86497.1 - 3.9e-05 23.3 0.0 0.0054 16.3 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EAQ86497.1 - 6.1e-05 23.1 0.4 0.00014 22.0 0.4 1.6 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 EAQ86497.1 - 0.0024 18.3 0.0 0.0066 16.9 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain F-box-like PF12937.7 EAQ86499.1 - 3.2e-05 23.7 0.3 7.6e-05 22.5 0.3 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EAQ86499.1 - 2.5 8.1 7.4 4.1 7.4 3.6 2.9 2 1 0 2 2 2 0 F-box domain Spt20 PF12090.8 EAQ86502.1 - 0.047 13.3 31.2 0.049 13.2 27.3 2.2 2 0 0 2 2 2 0 Spt20 family Activator_LAG-3 PF11498.8 EAQ86502.1 - 0.055 12.4 23.7 0.087 11.8 23.7 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 eIF-3_zeta PF05091.12 EAQ86502.1 - 0.23 10.4 10.5 0.33 9.9 10.5 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) SpoIIP PF07454.11 EAQ86502.1 - 0.25 10.8 8.8 0.4 10.1 8.8 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) RR_TM4-6 PF06459.12 EAQ86502.1 - 0.25 11.1 7.4 0.44 10.3 7.4 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4834 PF16118.5 EAQ86502.1 - 0.38 11.7 8.8 1.1 10.2 8.8 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) PAT1 PF09770.9 EAQ86502.1 - 0.53 8.5 17.0 0.75 8.0 17.0 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CPSF100_C PF13299.6 EAQ86502.1 - 0.56 10.4 8.0 1.4 9.1 8.0 1.7 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF4407 PF14362.6 EAQ86502.1 - 0.7 9.2 5.8 0.95 8.7 5.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) EphA2_TM PF14575.6 EAQ86502.1 - 0.84 10.6 9.0 1.8 9.5 8.8 1.7 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain MRP-S27 PF10037.9 EAQ86502.1 - 0.86 8.4 9.3 1.2 7.9 9.3 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 FAM60A PF15396.6 EAQ86502.1 - 1.1 9.2 6.3 3 7.8 6.3 1.6 1 0 0 1 1 1 0 Protein Family FAM60A TERB2 PF15101.6 EAQ86502.1 - 1.1 9.2 12.6 2.1 8.3 12.6 1.4 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Presenilin PF01080.17 EAQ86502.1 - 1.2 7.8 12.1 0.059 12.1 6.5 1.6 2 0 0 2 2 2 0 Presenilin V_ATPase_I PF01496.19 EAQ86502.1 - 1.2 7.0 6.1 1.6 6.6 6.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Connexin PF00029.19 EAQ86502.1 - 1.5 8.5 6.7 2.2 8.0 6.7 1.2 1 0 0 1 1 1 0 Connexin ALMT PF11744.8 EAQ86502.1 - 3.6 6.3 5.1 5.1 5.8 5.1 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter EIIBC-GUT_N PF03612.14 EAQ86502.1 - 5.1 6.8 11.9 12 5.6 11.9 1.5 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus AIF_C PF14721.6 EAQ86502.1 - 7.1 7.0 7.6 18 5.7 7.6 1.7 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF1980 PF09323.10 EAQ86502.1 - 8.7 6.2 6.5 18 5.2 6.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) DUF3464 PF11947.8 EAQ86502.1 - 9.2 6.0 12.0 2.6 7.8 8.6 1.8 2 0 0 2 2 1 0 Photosynthesis affected mutant 68 DUF5427 PF10310.9 EAQ86502.1 - 9.7 5.0 22.5 0.038 13.0 11.8 2.1 2 1 0 2 2 2 0 Family of unknown function (DUF5427) Glyco_hydro_61 PF03443.14 EAQ86503.1 - 6.2e-57 192.9 0.6 8.6e-57 192.4 0.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.18 EAQ86503.1 - 4e-12 45.9 12.6 1.1e-11 44.5 12.6 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain ELO PF01151.18 EAQ86504.1 - 4e-61 206.7 19.9 4.8e-61 206.5 19.9 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family COX5A PF02284.16 EAQ86505.1 - 6e-42 141.8 0.1 8e-42 141.4 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va DUF4972 PF16342.5 EAQ86505.1 - 0.062 13.0 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4972) Chromo PF00385.24 EAQ86506.1 - 3.3e-05 23.7 0.5 7.2e-05 22.6 0.5 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain HAP1_N PF04849.13 EAQ86506.1 - 0.0051 16.0 6.7 0.0051 16.0 6.7 3.1 2 1 1 3 3 3 3 HAP1 N-terminal conserved region Fez1 PF06818.15 EAQ86506.1 - 2 8.8 36.6 7.9 6.9 22.3 2.5 1 1 1 2 2 2 0 Fez1 Spc7 PF08317.11 EAQ86506.1 - 8.2 5.2 42.7 0.086 11.7 19.7 2.4 1 1 1 2 2 2 0 Spc7 kinetochore protein GAS PF13851.6 EAQ86506.1 - 8.8 5.6 40.7 21 4.4 29.0 2.8 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Glyco_transf_8 PF01501.20 EAQ86507.1 - 3.2e-24 85.9 1.0 1.2e-22 80.8 1.0 2.1 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 EAQ86507.1 - 0.074 12.4 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Mannosyltransferase putative Cation_efflux PF01545.21 EAQ86508.1 - 7.4e-15 55.2 8.0 9.7e-15 54.8 8.0 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 EAQ86508.1 - 5.9e-12 45.5 0.4 1.3e-11 44.5 0.4 1.5 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter TctB PF07331.11 EAQ86508.1 - 0.056 13.7 8.1 0.093 13.0 6.3 2.0 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family APH PF01636.23 EAQ86509.1 - 5.9e-07 29.6 0.1 2.9e-06 27.4 0.1 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Erythro-docking PF09277.11 EAQ86509.1 - 0.063 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Erythronolide synthase, docking Hydrolase_4 PF12146.8 EAQ86510.1 - 3.5e-23 82.1 0.0 9.2e-15 54.5 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EAQ86510.1 - 0.0036 17.0 0.5 0.0063 16.2 0.1 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EAQ86510.1 - 0.0068 17.0 7.9 0.012 16.2 2.8 2.0 1 1 1 2 2 2 2 Alpha/beta hydrolase family TB2_DP1_HVA22 PF03134.19 EAQ86512.1 - 3.9e-26 90.8 10.0 5.6e-26 90.3 10.0 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family DUF4407 PF14362.6 EAQ86512.1 - 0.21 10.9 1.0 1.1 8.5 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Mid1 PF12929.7 EAQ86513.1 - 8e-154 512.9 0.2 9.3e-154 512.7 0.2 1.0 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.22 EAQ86513.1 - 0.00037 21.1 3.1 0.033 14.8 1.1 2.5 2 0 0 2 2 2 2 Fz domain RAMP4 PF06624.12 EAQ86515.1 - 3.3e-22 78.3 0.2 3.7e-22 78.2 0.2 1.0 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 SMAP PF15477.6 EAQ86516.1 - 6.8e-10 39.8 3.5 6.8e-10 39.8 3.5 4.5 2 1 0 2 2 2 1 Small acidic protein family SNRNP27 PF08648.12 EAQ86517.1 - 2e-26 91.8 1.5 4.9e-26 90.6 1.5 1.7 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins Presenilin PF01080.17 EAQ86517.1 - 2.2 7.0 4.7 3.4 6.4 4.7 1.2 1 0 0 1 1 1 0 Presenilin ASXH PF13919.6 EAQ86518.1 - 1.9e-36 125.1 2.0 2.9e-36 124.5 2.0 1.3 1 0 0 1 1 1 1 Asx homology domain Peptidase_C24 PF03510.14 EAQ86518.1 - 0.024 15.1 0.1 0.041 14.4 0.1 1.3 1 0 0 1 1 1 0 2C endopeptidase (C24) cysteine protease family Longin PF13774.6 EAQ86519.1 - 5.1e-24 84.1 0.2 9.3e-24 83.3 0.1 1.5 2 0 0 2 2 2 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 EAQ86519.1 - 5.7e-14 51.7 0.0 1e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 Synaptobrevin DUF334 PF03904.13 EAQ86519.1 - 0.1 12.1 1.1 7.9 5.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF334) DUF1664 PF07889.12 EAQ86519.1 - 0.43 10.6 2.2 0.6 10.2 0.4 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Anti-TRAP PF15777.5 EAQ86520.1 - 0.067 13.2 0.3 3.1 7.8 0.0 2.8 3 0 0 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein PyrI_C PF02748.15 EAQ86520.1 - 0.095 12.6 1.1 2.8 7.9 0.0 2.3 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain CLPTM1 PF05602.12 EAQ86521.1 - 3.7e-157 523.8 0.0 4.5e-157 523.5 0.0 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) DUF1772 PF08592.11 EAQ86521.1 - 0.49 10.7 2.6 7 7.0 1.2 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) Lysine_decarbox PF03641.14 EAQ86522.1 - 3.6e-28 98.3 0.0 5.6e-28 97.7 0.0 1.3 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 EAQ86522.1 - 1.7e-06 27.7 2.8 9.9e-06 25.2 2.8 2.0 1 1 0 1 1 1 1 SLOG cluster4 family LSDAT_prok PF18171.1 EAQ86522.1 - 0.082 12.1 0.2 0.14 11.4 0.2 1.4 1 1 0 1 1 1 0 SLOG in TRPM, prokaryote Proteasome PF00227.26 EAQ86523.1 - 3.6e-51 173.3 0.0 4.6e-51 173.0 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EAQ86523.1 - 2.1e-11 43.3 0.2 3.7e-11 42.5 0.2 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Vps55 PF04133.14 EAQ86524.1 - 5.1e-44 149.0 9.1 5.8e-44 148.8 9.1 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 Chorismate_bind PF00425.18 EAQ86525.1 - 4.1e-64 216.6 0.3 7.9e-36 123.9 0.0 3.0 2 1 0 2 2 2 2 chorismate binding enzyme Anth_synt_I_N PF04715.13 EAQ86525.1 - 8.9e-14 51.9 0.0 2.8e-13 50.3 0.0 1.9 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region GATase PF00117.28 EAQ86525.1 - 7.2e-07 29.2 0.0 1.6e-05 24.8 0.0 2.3 2 0 0 2 2 2 1 Glutamine amidotransferase class-I Actino_peptide PF14408.6 EAQ86525.1 - 6.6 6.9 6.5 0.57 10.3 0.3 2.3 2 0 0 2 2 2 0 Ribosomally synthesised peptide in actinomycetes TRAPPC9-Trs120 PF08626.11 EAQ86526.1 - 0 1268.3 0.0 1.3e-208 695.3 0.0 2.0 1 1 1 2 2 2 2 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit adh_short PF00106.25 EAQ86527.1 - 1.3e-20 73.7 0.0 2.1e-20 73.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EAQ86527.1 - 1.4e-17 64.1 0.0 2.1e-17 63.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ZapB PF06005.12 EAQ86527.1 - 0.11 13.0 0.4 0.42 11.1 0.2 2.0 2 0 0 2 2 2 0 Cell division protein ZapB DUF2264 PF10022.9 EAQ86528.1 - 6.4e-105 351.1 5.9 2e-88 296.8 5.5 2.1 1 1 1 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2264) FH2 PF02181.23 EAQ86529.1 - 9.5e-74 248.7 6.4 9.5e-74 248.7 6.4 2.1 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.13 EAQ86529.1 - 3.4e-66 222.4 0.0 1.1e-65 220.8 0.0 1.9 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 EAQ86529.1 - 2.4e-51 174.2 5.3 2.4e-51 174.2 5.3 2.9 2 1 1 3 3 3 1 Diaphanous FH3 Domain GLTP PF08718.11 EAQ86529.1 - 0.18 12.1 0.9 1.4 9.2 0.0 2.8 3 0 0 3 3 3 0 Glycolipid transfer protein (GLTP) Methyltransf_5 PF01795.19 EAQ86529.1 - 0.34 10.4 6.4 0.029 13.9 1.5 1.7 2 0 0 2 2 2 0 MraW methylase family PPP5 PF08321.12 EAQ86531.1 - 1.8e-32 111.5 0.0 4.1e-32 110.3 0.0 1.6 1 0 0 1 1 1 1 PPP5 TPR repeat region Metallophos PF00149.28 EAQ86531.1 - 5.2e-19 69.6 0.1 3.9e-16 60.1 0.0 2.2 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase TPR_1 PF00515.28 EAQ86531.1 - 2e-18 65.3 0.1 7.3e-06 25.6 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 EAQ86531.1 - 1.8e-14 52.6 0.1 0.0003 20.7 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 EAQ86531.1 - 7.8e-12 44.7 0.4 1.2e-05 24.9 0.0 3.3 3 0 0 3 3 3 2 TPR repeat TPR_17 PF13431.6 EAQ86531.1 - 1.5e-08 34.4 0.9 0.011 16.0 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 EAQ86531.1 - 2.6e-07 30.3 0.1 0.0058 16.8 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 EAQ86531.1 - 1e-06 28.8 0.0 0.0086 16.2 0.0 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 EAQ86531.1 - 7.4e-06 26.5 0.1 0.0027 18.3 0.0 2.4 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 EAQ86531.1 - 2e-05 25.0 0.0 0.18 12.3 0.0 3.0 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 EAQ86531.1 - 0.00015 22.3 0.2 0.18 12.7 0.0 2.9 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_15 PF13429.6 EAQ86531.1 - 0.00064 19.0 0.1 0.029 13.6 0.1 2.1 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 EAQ86531.1 - 0.016 15.8 1.1 0.33 11.7 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 EAQ86531.1 - 0.023 15.0 0.3 4.6 7.6 0.2 3.1 1 1 1 2 2 2 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 EAQ86531.1 - 0.16 11.4 0.0 5.2 6.6 0.0 2.6 3 0 0 3 3 3 0 SHNi-TPR EBP50_C PF09007.11 EAQ86532.1 - 0.54 11.3 5.8 0.73 10.8 5.8 1.1 1 0 0 1 1 1 0 EBP50, C-terminal Pkinase PF00069.25 EAQ86534.1 - 4.3e-46 157.4 0.0 7.8e-34 117.2 0.1 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ86534.1 - 3.2e-19 69.2 0.1 4.9e-19 68.6 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAQ86534.1 - 0.042 13.2 0.1 0.12 11.6 0.0 1.7 1 1 1 2 2 2 0 Kinase-like DUF3678 PF12435.8 EAQ86534.1 - 2.2 7.8 4.3 7.8 6.0 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3678) P5-ATPase PF12409.8 EAQ86535.1 - 8.8e-42 142.1 0.1 2e-41 141.0 0.1 1.6 1 0 0 1 1 1 1 P5-type ATPase cation transporter Hydrolase PF00702.26 EAQ86535.1 - 8.2e-17 62.2 0.4 5.8e-10 39.8 0.1 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 EAQ86535.1 - 6.3e-13 48.6 0.4 1.7e-12 47.3 0.4 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 EAQ86535.1 - 0.0004 20.1 3.5 0.0004 20.1 3.5 1.8 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Cation_ATPase_N PF00690.26 EAQ86535.1 - 0.0029 17.2 0.0 0.0058 16.3 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EAQ86535.1 - 0.076 12.7 0.0 7 6.3 0.0 2.6 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EAQ86535.1 - 0.13 12.4 0.0 0.32 11.1 0.0 1.6 1 0 0 1 1 1 0 Cation transport ATPase (P-type) NAP PF00956.18 EAQ86536.1 - 1.5e-99 332.6 8.5 1.5e-99 332.6 8.5 1.7 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) Striatin PF08232.12 EAQ86536.1 - 0.029 14.9 1.0 0.029 14.9 1.0 2.8 2 1 0 2 2 2 0 Striatin family 2-Hacid_dh_C PF02826.19 EAQ86537.1 - 5.7e-52 175.7 0.0 9.3e-52 175.0 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EAQ86537.1 - 8e-38 129.1 0.1 1.1e-37 128.7 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EAQ86537.1 - 1.2e-05 25.6 0.1 2.9e-05 24.3 0.1 1.7 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.21 EAQ86537.1 - 0.00078 19.5 0.1 0.0022 18.1 0.0 1.7 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IlvN PF07991.12 EAQ86537.1 - 0.0011 18.5 0.1 0.036 13.6 0.0 2.5 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain ACT PF01842.25 EAQ86537.1 - 0.0057 16.4 0.0 0.021 14.6 0.0 2.1 1 0 0 1 1 1 1 ACT domain XdhC_C PF13478.6 EAQ86537.1 - 0.022 15.3 0.0 0.12 12.9 0.0 2.1 2 0 0 2 2 2 0 XdhC Rossmann domain 3HCDH_N PF02737.18 EAQ86537.1 - 0.21 11.5 2.1 2.4 8.0 0.4 2.9 2 1 1 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Myosin_head PF00063.21 EAQ86538.1 - 2e-199 664.2 0.0 3.9e-125 418.7 0.2 2.8 1 1 1 2 2 2 2 Myosin head (motor domain) DIL PF01843.19 EAQ86538.1 - 1.6e-26 92.6 3.0 7.1e-26 90.5 3.0 2.3 1 0 0 1 1 1 1 DIL domain IQ PF00612.27 EAQ86538.1 - 1.4e-11 43.2 39.1 5.2e-06 25.8 1.9 6.9 6 0 0 6 6 6 4 IQ calmodulin-binding motif GAS PF13851.6 EAQ86538.1 - 1.5e-05 24.4 12.1 1.5e-05 24.4 12.1 2.6 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding AAA_16 PF13191.6 EAQ86538.1 - 0.014 15.8 3.1 0.036 14.5 0.0 2.8 2 0 0 2 2 2 0 AAA ATPase domain Myosin_N PF02736.19 EAQ86538.1 - 0.015 15.1 0.7 0.015 15.1 0.7 1.8 2 0 0 2 2 1 0 Myosin N-terminal SH3-like domain FlaC_arch PF05377.11 EAQ86538.1 - 0.039 14.3 9.0 0.056 13.8 0.2 3.7 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) AAA_22 PF13401.6 EAQ86538.1 - 0.045 14.0 0.0 0.19 12.0 0.0 2.1 1 0 0 1 1 1 0 AAA domain DUF812 PF05667.11 EAQ86538.1 - 0.054 12.4 25.3 0.093 11.6 25.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) FlgN PF05130.12 EAQ86538.1 - 0.12 12.9 14.6 0.033 14.7 10.4 2.3 1 1 1 2 2 2 0 FlgN protein APG6_N PF17675.1 EAQ86538.1 - 0.73 10.4 31.2 0.11 13.1 23.5 3.0 1 1 1 2 2 2 0 Apg6 coiled-coil region Fez1 PF06818.15 EAQ86538.1 - 2.1 8.8 30.1 0.1 13.0 10.7 2.8 2 1 1 3 3 3 0 Fez1 zf-C4H2 PF10146.9 EAQ86538.1 - 2.5 8.4 8.3 7.9 6.7 8.3 1.9 1 0 0 1 1 1 0 Zinc finger-containing protein Baculo_PEP_C PF04513.12 EAQ86538.1 - 4.3 7.4 12.1 15 5.6 9.4 3.1 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ABC_tran PF00005.27 EAQ86538.1 - 6 7.4 5.9 1.7 9.1 0.0 2.9 2 1 0 2 2 1 0 ABC transporter AAA_18 PF13238.6 EAQ86539.1 - 1.1e-28 100.3 1.0 3.1e-28 98.9 0.1 1.8 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 EAQ86539.1 - 1.5e-07 31.9 0.1 6.9e-07 29.8 0.0 2.1 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 EAQ86539.1 - 2.4e-05 24.5 0.1 0.022 14.9 0.0 2.3 1 1 1 2 2 2 2 AAA domain AAA_28 PF13521.6 EAQ86539.1 - 8.7e-05 22.8 0.9 0.00017 21.9 0.8 1.8 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 EAQ86539.1 - 0.00034 21.1 0.0 0.0013 19.2 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) SKI PF01202.22 EAQ86539.1 - 0.00045 20.4 1.0 0.005 17.0 1.0 2.0 1 1 0 1 1 1 1 Shikimate kinase dNK PF01712.19 EAQ86539.1 - 0.0018 18.2 3.8 0.1 12.4 0.9 2.1 1 1 1 2 2 2 2 Deoxynucleoside kinase ADK PF00406.22 EAQ86539.1 - 0.003 17.7 0.0 0.18 11.9 0.0 2.2 2 0 0 2 2 2 1 Adenylate kinase Hydin_ADK PF17213.3 EAQ86539.1 - 0.0049 17.2 0.0 0.011 16.0 0.0 1.6 2 0 0 2 2 2 1 Hydin Adenylate kinase-like domain Thymidylate_kin PF02223.17 EAQ86539.1 - 0.0075 16.0 0.5 2.8 7.6 0.1 2.2 2 0 0 2 2 2 2 Thymidylate kinase AAA_5 PF07728.14 EAQ86539.1 - 0.018 15.0 0.0 0.033 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EAQ86539.1 - 0.03 14.7 0.5 0.073 13.5 0.5 1.9 1 1 0 1 1 1 0 AAA ATPase domain KTI12 PF08433.10 EAQ86539.1 - 0.037 13.5 0.0 0.11 11.9 0.0 1.7 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_22 PF13401.6 EAQ86539.1 - 0.056 13.7 0.0 0.2 11.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.12 EAQ86539.1 - 0.2 11.4 0.2 0.44 10.3 0.0 1.6 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_30 PF13604.6 EAQ86539.1 - 0.89 9.2 6.7 6.6 6.4 0.0 2.6 2 1 1 3 3 3 0 AAA domain AAA_19 PF13245.6 EAQ86539.1 - 6.1 7.2 5.9 0.77 10.1 0.8 2.1 2 1 1 3 3 3 0 AAA domain Ham1p_like PF01725.16 EAQ86540.1 - 1.1e-57 195.0 0.0 1.2e-57 194.9 0.0 1.0 1 0 0 1 1 1 1 Ham1 family Peptidase_C78 PF07910.13 EAQ86541.1 - 9.8e-51 172.2 0.0 3.5e-50 170.4 0.0 1.8 1 1 1 2 2 2 1 Peptidase family C78 Peptidase_C47 PF05543.13 EAQ86541.1 - 0.03 13.9 0.0 0.057 13.0 0.0 1.3 1 0 0 1 1 1 0 Staphopain peptidase C47 tRNA-synt_2b PF00587.25 EAQ86542.1 - 2e-34 119.1 0.0 2.9e-34 118.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 EAQ86542.1 - 8.9e-11 42.0 0.4 1.9e-10 40.9 0.4 1.6 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Ras PF00071.22 EAQ86543.1 - 3.9e-47 159.9 0.1 4.4e-47 159.7 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAQ86543.1 - 1e-16 61.2 0.0 1.4e-16 60.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAQ86543.1 - 6.7e-08 32.2 0.0 7.6e-08 32.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EAQ86543.1 - 3e-05 23.6 0.0 0.00014 21.4 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EAQ86543.1 - 8.3e-05 22.5 0.0 0.018 15.0 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EAQ86543.1 - 0.00036 20.6 0.0 0.00056 20.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 EAQ86543.1 - 0.0029 17.1 0.0 0.0043 16.5 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_14 PF13173.6 EAQ86543.1 - 0.12 12.4 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain WAPL PF07814.13 EAQ86544.1 - 3e-80 269.8 0.8 4.5e-80 269.2 0.8 1.2 1 0 0 1 1 1 1 Wings apart-like protein regulation of heterochromatin UPRTase PF14681.6 EAQ86545.1 - 7.7e-80 267.2 0.0 1e-79 266.8 0.0 1.1 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 EAQ86545.1 - 0.0026 17.3 0.0 0.0041 16.6 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Elf1 PF05129.13 EAQ86546.1 - 7.9e-21 73.9 5.2 1.5e-20 73.0 5.2 1.4 1 1 0 1 1 1 1 Transcription elongation factor Elf1 like PHD_4 PF16866.5 EAQ86546.1 - 0.013 15.6 2.2 0.026 14.6 2.2 1.5 1 0 0 1 1 1 0 PHD-finger zf-Sec23_Sec24 PF04810.15 EAQ86546.1 - 0.16 12.1 3.2 3.3 7.8 0.1 2.3 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger GTP_CH_N PF12471.8 EAQ86547.1 - 4.1e-84 281.1 0.0 6e-84 280.6 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal Secretin_N PF03958.17 EAQ86548.1 - 0.012 16.0 0.2 0.022 15.2 0.2 1.4 1 1 0 1 1 1 0 Bacterial type II/III secretion system short domain Ribosomal_S3Ae PF01015.18 EAQ86550.1 - 4.8e-88 294.0 1.7 5.8e-88 293.8 1.7 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family SUI1 PF01253.22 EAQ86550.1 - 0.028 15.0 0.1 0.11 13.0 0.0 2.0 2 0 0 2 2 2 0 Translation initiation factor SUI1 NEMO PF11577.8 EAQ86550.1 - 0.053 13.5 0.8 0.31 11.1 0.0 2.3 2 0 0 2 2 2 0 NF-kappa-B essential modulator NEMO Abhydrolase_1 PF00561.20 EAQ86551.1 - 6.7e-22 78.4 0.1 5.4e-21 75.4 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EAQ86551.1 - 2.7e-16 60.8 1.3 4e-16 60.3 1.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EAQ86551.1 - 5.8e-08 32.3 0.1 1.3e-07 31.2 0.1 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 EAQ86551.1 - 1.9e-05 24.9 0.0 3.1e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.13 EAQ86551.1 - 2e-05 24.4 0.2 0.054 13.2 0.1 2.2 1 1 1 2 2 2 2 PGAP1-like protein Esterase PF00756.20 EAQ86551.1 - 0.001 18.8 0.0 0.0013 18.4 0.0 1.2 1 0 0 1 1 1 1 Putative esterase UPF0227 PF05728.12 EAQ86551.1 - 0.039 13.9 0.0 0.054 13.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Chlorophyllase2 PF12740.7 EAQ86551.1 - 0.14 11.0 0.0 0.26 10.2 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Chlorophyllase PF07224.11 EAQ86551.1 - 0.16 10.9 0.0 0.29 10.1 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase MCR_C PF04609.12 EAQ86551.1 - 0.25 10.4 0.1 0.49 9.4 0.0 1.4 2 0 0 2 2 2 0 Methyl-coenzyme M reductase operon protein C SRP_TPR_like PF17004.5 EAQ86552.1 - 2.7e-22 79.0 0.0 3.2e-20 72.3 0.0 2.5 2 0 0 2 2 2 1 Putative TPR-like repeat SRP72 PF08492.12 EAQ86552.1 - 1.2e-16 60.8 13.5 1.2e-16 60.8 13.5 2.0 2 0 0 2 2 2 1 SRP72 RNA-binding domain TPR_12 PF13424.6 EAQ86552.1 - 4.7e-06 26.8 20.6 0.21 11.9 0.6 6.7 6 1 1 7 7 7 3 Tetratricopeptide repeat ANAPC3 PF12895.7 EAQ86552.1 - 0.00015 21.9 6.0 0.012 15.8 1.3 4.8 4 1 1 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 EAQ86552.1 - 0.00061 20.3 23.4 0.5 10.9 0.2 6.7 4 2 3 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 EAQ86552.1 - 0.00071 20.2 34.2 7.2 7.7 0.0 10.2 8 2 3 11 11 11 2 Tetratricopeptide repeat TPR_9 PF13371.6 EAQ86552.1 - 0.0069 16.5 0.2 0.0069 16.5 0.2 3.9 6 0 0 6 6 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 EAQ86552.1 - 0.011 15.9 2.3 5.8 7.4 0.3 5.1 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 EAQ86552.1 - 0.015 15.4 19.4 2.7 8.3 0.6 7.1 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_16 PF13432.6 EAQ86552.1 - 0.02 15.6 1.4 0.02 15.6 1.4 7.4 6 2 1 7 7 7 0 Tetratricopeptide repeat REV1_C PF16727.5 EAQ86552.1 - 0.16 12.4 0.1 0.39 11.1 0.1 1.6 1 0 0 1 1 1 0 DNA repair protein REV1 C-terminal domain TPR_10 PF13374.6 EAQ86552.1 - 0.8 9.7 13.8 32 4.6 0.0 6.5 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_7 PF13176.6 EAQ86552.1 - 4 7.7 7.3 8.4 6.7 0.1 4.3 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 EAQ86552.1 - 6.8 7.6 26.9 0.98 10.2 0.1 7.6 8 1 1 9 9 7 0 Tetratricopeptide repeat Sec7 PF01369.20 EAQ86553.1 - 7.2e-31 107.3 0.1 1.1e-30 106.7 0.1 1.2 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.6 EAQ86553.1 - 9.6e-06 26.0 0.0 2.5e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 EAQ86553.1 - 1.3e-05 25.7 0.2 3.6e-05 24.2 0.2 1.8 1 1 0 1 1 1 1 PH domain Peptidase_M14 PF00246.24 EAQ86554.1 - 2.2e-78 264.0 0.0 2.7e-78 263.7 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase MFS_1 PF07690.16 EAQ86556.1 - 1.3e-16 60.5 38.1 2.6e-14 52.9 11.1 2.8 1 1 2 3 3 3 3 Major Facilitator Superfamily MS_channel PF00924.18 EAQ86556.1 - 1.1 8.8 3.6 3.1 7.3 3.6 1.7 1 0 0 1 1 1 0 Mechanosensitive ion channel FAD_binding_4 PF01565.23 EAQ86557.1 - 1e-15 57.7 2.0 2e-15 56.7 2.0 1.5 1 0 0 1 1 1 1 FAD binding domain Amidoligase_2 PF12224.8 EAQ86558.1 - 2.8e-14 53.4 0.0 3.8e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 Putative amidoligase enzyme HTH_Tnp_Tc3_2 PF01498.18 EAQ86559.1 - 2.6e-21 75.6 1.7 2.6e-21 75.6 1.7 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 EAQ86559.1 - 1.2e-12 47.9 0.2 2.7e-12 46.7 0.2 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.6 EAQ86559.1 - 2.1e-06 27.6 2.2 3e-05 23.9 0.5 2.6 2 0 0 2 2 2 1 Winged helix-turn helix HTH_32 PF13565.6 EAQ86559.1 - 3.4e-06 27.6 2.9 7e-06 26.6 1.2 2.3 1 1 1 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 EAQ86559.1 - 0.00094 19.3 1.0 0.0078 16.3 0.2 2.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 EAQ86559.1 - 0.012 15.4 0.2 0.012 15.4 0.2 2.8 4 0 0 4 4 4 0 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.6 EAQ86559.1 - 0.016 14.6 8.8 0.028 13.8 0.3 3.9 4 0 0 4 4 4 0 Helix-turn-helix domain of transposase family ISL3 HTH_7 PF02796.15 EAQ86559.1 - 0.017 15.2 0.0 0.19 11.8 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase CENP-B_N PF04218.13 EAQ86559.1 - 0.036 13.7 0.2 1.6 8.4 0.0 3.2 3 0 0 3 3 3 0 CENP-B N-terminal DNA-binding domain HTH_38 PF13936.6 EAQ86559.1 - 0.045 13.5 0.0 0.045 13.5 0.0 2.4 3 0 0 3 3 3 0 Helix-turn-helix domain Pyr_redox_2 PF07992.14 EAQ86561.1 - 1.8e-28 99.6 0.0 2.5e-28 99.2 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EAQ86561.1 - 3.6e-13 49.9 0.1 2.8e-10 40.6 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EAQ86561.1 - 0.0033 16.6 0.0 0.0067 15.6 0.0 1.4 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) MAP65_ASE1 PF03999.12 EAQ86561.1 - 0.0061 15.3 0.5 0.0083 14.9 0.5 1.1 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) Sacchrp_dh_NADP PF03435.18 EAQ86561.1 - 0.03 14.6 0.2 11 6.2 0.0 2.3 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 EAQ86561.1 - 0.068 13.4 0.4 3 8.1 0.3 2.7 2 1 0 2 2 2 0 TrkA-N domain ORC6 PF05460.13 EAQ86563.1 - 3.5 6.8 13.3 3.9e+02 0.1 13.3 2.2 1 1 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Rep_fac-A_3 PF08661.11 EAQ86564.1 - 8.6e-22 77.5 0.0 9.4e-22 77.4 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 bZIP_1 PF00170.21 EAQ86565.1 - 7.6e-08 32.3 8.9 1e-07 31.9 8.9 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EAQ86565.1 - 1e-06 28.7 9.1 1.8e-06 27.9 9.1 1.4 1 0 0 1 1 1 1 Basic region leucine zipper APG6_N PF17675.1 EAQ86565.1 - 0.0067 17.0 0.6 0.0084 16.6 0.6 1.2 1 0 0 1 1 1 1 Apg6 coiled-coil region GOLGA2L5 PF15070.6 EAQ86565.1 - 0.0099 14.6 0.6 0.012 14.4 0.6 1.1 1 0 0 1 1 1 1 Putative golgin subfamily A member 2-like protein 5 DUF3999 PF13163.6 EAQ86565.1 - 0.019 14.2 0.8 0.025 13.8 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3999) Atg14 PF10186.9 EAQ86565.1 - 0.023 13.8 3.4 0.028 13.5 3.4 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 NAM-associated PF14303.6 EAQ86565.1 - 0.023 15.4 1.7 0.031 15.0 1.7 1.2 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain bZIP_Maf PF03131.17 EAQ86565.1 - 0.1 13.1 5.9 0.17 12.4 5.9 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor DUF4407 PF14362.6 EAQ86565.1 - 0.12 11.7 1.5 0.15 11.4 1.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DivIC PF04977.15 EAQ86565.1 - 0.37 10.6 3.3 0.59 10.0 3.3 1.3 1 0 0 1 1 1 0 Septum formation initiator Alb1 PF09135.11 EAQ86566.1 - 5.2e-29 101.2 10.7 5.2e-29 101.2 10.7 1.4 2 0 0 2 2 2 1 Alb1 Bd3614_N PF14442.6 EAQ86566.1 - 0.22 11.8 3.2 0.69 10.3 3.2 2.0 1 1 0 1 1 1 0 Bd3614-like deaminase N-terminal RHH_7 PF16777.5 EAQ86566.1 - 2.6 8.5 6.4 10 6.6 1.5 3.0 2 1 0 2 2 2 0 Transcriptional regulator, RHH-like, CopG UCH PF00443.29 EAQ86567.1 - 1.3e-32 113.4 0.0 2.2e-32 112.6 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EAQ86567.1 - 1e-07 31.9 0.0 3.9e-06 26.7 0.0 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Med11 PF10280.9 EAQ86567.1 - 0.085 13.3 0.0 0.18 12.3 0.0 1.5 1 0 0 1 1 1 0 Mediator complex protein Octopine_DH PF02317.17 EAQ86567.1 - 0.085 12.9 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain TPT PF03151.16 EAQ86568.1 - 1.2e-14 54.4 20.2 2e-08 33.9 7.7 2.1 1 1 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.20 EAQ86568.1 - 3.1e-05 24.2 32.2 0.0039 17.4 11.3 2.6 3 0 0 3 3 3 2 EamA-like transporter family UAA PF08449.11 EAQ86568.1 - 0.0014 17.9 14.5 0.0078 15.4 2.3 2.2 1 1 0 2 2 2 2 UAA transporter family COMPASS-Shg1 PF05205.12 EAQ86569.1 - 1.4e-24 86.7 0.0 3.5e-24 85.5 0.0 1.7 1 0 0 1 1 1 1 COMPASS (Complex proteins associated with Set1p) component shg1 G2BR PF18442.1 EAQ86570.1 - 0.17 11.5 5.3 0.29 10.8 5.3 1.3 1 0 0 1 1 1 0 E3 gp78 Ube2g2-binding region (G2BR) IF-2B PF01008.17 EAQ86571.1 - 7.2e-45 153.4 0.0 1.8e-44 152.1 0.0 1.5 1 1 0 1 1 1 1 Initiation factor 2 subunit family Stig1 PF04885.13 EAQ86571.1 - 0.0014 19.1 19.0 0.0014 19.1 19.0 2.6 2 1 1 3 3 3 1 Stigma-specific protein, Stig1 IF3_C PF00707.22 EAQ86572.1 - 3.2e-06 27.0 0.2 5e-06 26.4 0.2 1.3 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain mIF3 PF14877.6 EAQ86572.1 - 0.027 14.1 0.0 0.054 13.2 0.0 1.5 1 1 0 1 1 1 0 Mitochondrial translation initiation factor Peptidase_S24 PF00717.23 EAQ86573.1 - 1.1e-07 31.6 0.1 2.5e-07 30.5 0.0 1.6 2 0 0 2 2 2 1 Peptidase S24-like Arm PF00514.23 EAQ86574.1 - 5.6e-74 242.2 29.2 3.9e-13 48.9 0.2 11.2 11 0 0 11 11 11 9 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 EAQ86574.1 - 7e-21 74.3 14.9 7.1e-06 26.4 0.1 7.7 7 2 2 9 9 7 5 HEAT-like repeat HEAT_2 PF13646.6 EAQ86574.1 - 4.7e-16 58.9 9.3 0.00068 20.0 0.1 7.0 5 2 0 6 6 6 4 HEAT repeats HEAT PF02985.22 EAQ86574.1 - 1.1e-14 53.2 13.4 0.15 12.4 0.0 8.6 10 0 0 10 10 8 5 HEAT repeat Adaptin_N PF01602.20 EAQ86574.1 - 2.6e-10 39.5 8.0 1.8e-06 26.8 0.7 2.8 1 1 2 3 3 3 2 Adaptin N terminal region KAP PF05804.12 EAQ86574.1 - 5.5e-10 38.0 0.9 1e-09 37.1 0.9 1.4 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) V-ATPase_H_N PF03224.14 EAQ86574.1 - 5.9e-10 38.9 3.4 4.1e-06 26.3 1.1 3.4 2 1 1 3 3 3 2 V-ATPase subunit H Arm_2 PF04826.13 EAQ86574.1 - 3e-09 36.7 8.1 2.9e-05 23.7 3.9 3.0 1 1 2 3 3 3 3 Armadillo-like Cnd1 PF12717.7 EAQ86574.1 - 8e-07 29.2 5.6 0.0097 16.0 0.2 5.0 2 1 2 5 5 5 2 non-SMC mitotic condensation complex subunit 1 DUF3361 PF11841.8 EAQ86574.1 - 8.3e-05 22.6 7.5 0.57 10.1 0.1 4.1 2 1 2 4 4 4 2 Domain of unknown function (DUF3361) V-ATPase_H_C PF11698.8 EAQ86574.1 - 0.00078 19.6 4.7 18 5.4 0.1 5.0 2 1 5 7 7 6 0 V-ATPase subunit H HEAT_PBS PF03130.16 EAQ86574.1 - 0.017 15.7 6.3 92 4.2 0.1 6.6 6 0 0 6 6 6 0 PBS lyase HEAT-like repeat UNC45-central PF11701.8 EAQ86574.1 - 0.032 14.2 2.3 11 6.0 0.1 3.4 2 1 0 3 3 3 0 Myosin-binding striated muscle assembly central Vac14_Fab1_bd PF12755.7 EAQ86574.1 - 0.061 13.9 0.2 1.3 9.7 0.1 3.1 2 1 2 4 4 3 0 Vacuolar 14 Fab1-binding region RTP1_C1 PF10363.9 EAQ86574.1 - 0.081 13.1 2.6 54 4.0 0.0 4.4 3 1 1 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 Atx10homo_assoc PF09759.9 EAQ86574.1 - 0.19 11.8 9.9 2.9 8.0 0.4 4.8 3 2 2 5 5 5 0 Spinocerebellar ataxia type 10 protein domain CBS PF00571.28 EAQ86575.1 - 2.5e-26 91.9 9.3 3.6e-11 43.3 0.3 4.3 4 0 0 4 4 4 4 CBS domain RhoGAP PF00620.27 EAQ86576.1 - 0.0004 20.2 0.0 0.0021 17.9 0.0 1.9 1 1 1 2 2 2 1 RhoGAP domain PBP PF01161.20 EAQ86577.1 - 1.7e-09 38.1 0.0 2.8e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Ribosomal_L4 PF00573.22 EAQ86578.1 - 2.1e-44 151.5 0.0 2.9e-44 151.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Rox3 PF08633.10 EAQ86579.1 - 1.8e-67 227.6 0.5 1.8e-67 227.6 0.5 1.5 2 0 0 2 2 2 1 Rox3 mediator complex subunit DUF676 PF05057.14 EAQ86580.1 - 2.2e-06 27.3 0.0 4.1e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 EAQ86580.1 - 3.3e-06 27.9 0.3 9.3e-06 26.4 0.3 1.9 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 EAQ86580.1 - 3.5e-06 26.9 0.2 4.9e-05 23.2 0.0 2.2 1 1 1 2 2 2 1 PGAP1-like protein Hydrolase_4 PF12146.8 EAQ86580.1 - 0.0024 17.2 0.0 0.0047 16.2 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 EAQ86580.1 - 0.0028 17.8 1.6 0.083 13.0 0.0 2.2 2 0 0 2 2 2 1 Thioesterase domain UPF0227 PF05728.12 EAQ86580.1 - 0.013 15.5 0.0 0.013 15.5 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) GAGA_bind PF06217.12 EAQ86580.1 - 0.12 12.6 7.4 0.22 11.8 7.4 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family AP1AR PF15745.5 EAQ86580.1 - 0.15 11.6 1.8 0.24 11.0 1.8 1.2 1 0 0 1 1 1 0 AP-1 complex-associated regulatory protein SAGA-Tad1 PF12767.7 EAQ86580.1 - 0.61 9.8 8.1 1.1 9.0 8.1 1.4 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit SKA1 PF07160.12 EAQ86580.1 - 6.7 6.5 10.1 14 5.4 10.1 1.4 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 ATP-grasp_2 PF08442.10 EAQ86581.1 - 5.6e-46 156.7 3.4 9.1e-27 93.9 0.1 2.8 3 0 0 3 3 3 2 ATP-grasp domain Ligase_CoA PF00549.19 EAQ86581.1 - 2.2e-26 92.5 0.5 4e-26 91.7 0.5 1.5 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 EAQ86581.1 - 1.4e-06 27.9 0.2 1.4e-05 24.6 0.2 2.4 1 1 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 EAQ86581.1 - 0.00085 19.1 0.1 0.01 15.6 0.0 2.1 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain PALP PF00291.25 EAQ86581.1 - 0.06 12.8 0.3 0.43 10.0 0.0 2.2 3 0 0 3 3 3 0 Pyridoxal-phosphate dependent enzyme GlcNAc PF11397.8 EAQ86581.1 - 0.2 11.1 0.2 0.29 10.5 0.2 1.2 1 0 0 1 1 1 0 Glycosyltransferase (GlcNAc) p450 PF00067.22 EAQ86583.1 - 1.2e-10 40.7 0.0 1.4e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Mcl1_mid PF12341.8 EAQ86585.1 - 7.5e-96 321.0 0.0 1.1e-94 317.2 0.0 2.5 3 0 0 3 3 3 1 Minichromosome loss protein, Mcl1, middle region WD40 PF00400.32 EAQ86585.1 - 1.9e-22 79.1 0.5 7.2e-08 33.0 0.1 7.2 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAQ86585.1 - 6.9e-15 55.1 0.0 0.00042 20.5 0.1 6.7 3 1 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EAQ86585.1 - 0.00018 21.5 0.0 0.0011 18.9 0.0 2.2 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.14 EAQ86585.1 - 0.00072 18.7 0.0 0.0013 17.9 0.0 1.4 1 0 0 1 1 1 1 Coatomer WD associated region Ge1_WD40 PF16529.5 EAQ86585.1 - 0.0017 17.4 0.0 1.3 7.9 0.0 3.5 1 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Gmad1 PF10647.9 EAQ86585.1 - 0.006 16.4 0.0 3.2 7.4 0.0 2.7 2 1 1 3 3 3 2 Lipoprotein LpqB beta-propeller domain WD40_3 PF15911.5 EAQ86585.1 - 0.0064 16.5 0.0 1 9.4 0.0 3.7 4 0 0 4 4 4 1 WD domain, G-beta repeat PD40 PF07676.12 EAQ86585.1 - 0.037 14.0 0.0 19 5.3 0.0 4.2 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat IKI3 PF04762.12 EAQ86585.1 - 0.06 11.3 0.1 0.22 9.5 0.1 1.5 1 1 0 1 1 1 0 IKI3 family DNA_pol_alpha_N PF12254.8 EAQ86585.1 - 0.14 12.3 1.7 0.36 10.9 1.7 1.6 1 0 0 1 1 1 0 DNA polymerase alpha subunit p180 N terminal MMS1_N PF10433.9 EAQ86585.1 - 0.14 10.7 0.0 0.82 8.2 0.0 2.2 2 1 0 3 3 3 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term WD40 PF00400.32 EAQ86587.1 - 5.3e-07 30.2 7.7 0.17 12.8 0.3 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat Sigma70_r1_2 PF00140.20 EAQ86587.1 - 0.011 15.7 0.9 0.021 14.8 0.9 1.5 1 0 0 1 1 1 0 Sigma-70 factor, region 1.2 DUF627 PF04781.12 EAQ86587.1 - 0.012 15.6 0.0 0.02 14.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF627) QWRF PF04484.12 EAQ86588.1 - 8.2 6.1 6.9 26 4.4 6.9 1.8 1 0 0 1 1 1 0 QWRF family Ras PF00071.22 EAQ86589.1 - 2e-65 219.3 0.5 2.4e-65 219.1 0.5 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAQ86589.1 - 6.9e-36 123.1 0.1 1.3e-35 122.2 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAQ86589.1 - 3.4e-16 59.2 0.1 4.2e-16 58.9 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EAQ86589.1 - 6.5e-06 26.2 0.4 0.12 12.3 0.1 2.3 1 1 1 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EAQ86589.1 - 2.4e-05 24.4 0.0 9.5e-05 22.5 0.0 1.8 1 1 1 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EAQ86589.1 - 3.1e-05 23.6 0.5 7.2e-05 22.4 0.5 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EAQ86589.1 - 0.00023 20.6 0.1 0.00032 20.1 0.1 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EAQ86589.1 - 0.00051 19.5 0.0 0.00086 18.8 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 EAQ86589.1 - 0.00089 18.8 0.0 0.0057 16.2 0.0 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA PF00004.29 EAQ86589.1 - 0.0021 18.5 0.1 0.15 12.5 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EAQ86589.1 - 0.0091 16.4 0.0 0.013 15.9 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain Septin PF00735.18 EAQ86589.1 - 0.017 14.4 0.1 0.18 11.0 0.0 2.1 2 0 0 2 2 2 0 Septin AAA_22 PF13401.6 EAQ86589.1 - 0.033 14.4 0.0 0.068 13.4 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EAQ86589.1 - 0.048 13.4 0.0 0.16 11.8 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain TniB PF05621.11 EAQ86589.1 - 0.068 12.6 0.0 0.21 11.0 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein AAA_5 PF07728.14 EAQ86589.1 - 0.075 13.0 0.0 0.12 12.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 EAQ86589.1 - 0.087 12.3 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region PduV-EutP PF10662.9 EAQ86589.1 - 0.1 12.3 0.1 0.69 9.7 0.1 2.2 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 EAQ86589.1 - 0.11 13.0 0.0 0.17 12.4 0.0 1.5 1 1 0 1 1 1 0 ABC transporter WD40 PF00400.32 EAQ86590.1 - 5.7e-27 93.4 3.8 1.4e-10 41.5 0.2 4.3 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAQ86590.1 - 1.1e-09 38.5 0.0 0.0015 18.8 0.0 3.4 2 1 2 4 4 3 2 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 EAQ86590.1 - 1.8e-08 34.5 0.0 3.8e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EAQ86590.1 - 7.5e-06 26.4 0.1 2.9e-05 24.5 0.1 2.0 1 0 0 1 1 1 1 AAA ATPase domain PD40 PF07676.12 EAQ86590.1 - 3.2e-05 23.7 0.1 1.8 8.6 0.0 3.5 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 EAQ86590.1 - 3.7e-05 22.8 0.1 0.085 11.8 0.0 2.4 1 1 1 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein KAP_NTPase PF07693.14 EAQ86590.1 - 0.0056 16.0 0.7 0.014 14.6 0.7 1.8 1 1 0 1 1 1 1 KAP family P-loop domain DUF746 PF05344.11 EAQ86590.1 - 0.017 14.9 0.0 0.26 11.1 0.1 2.8 2 0 0 2 2 2 0 Domain of Unknown Function (DUF746) CENP-B_N PF04218.13 EAQ86590.1 - 0.037 13.7 0.0 0.11 12.1 0.0 1.8 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain HTH_IclR PF09339.10 EAQ86590.1 - 0.043 13.6 1.5 0.078 12.8 0.0 2.3 2 0 0 2 2 2 0 IclR helix-turn-helix domain AAA_22 PF13401.6 EAQ86590.1 - 0.048 13.9 0.0 0.22 11.8 0.0 2.2 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 EAQ86590.1 - 0.12 11.5 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) CbiA PF01656.23 EAQ86590.1 - 0.16 12.0 0.1 2.3 8.3 0.0 2.4 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain MMU163 PF17119.5 EAQ86591.1 - 4.5e-51 173.4 2.8 6e-51 173.0 2.8 1.1 1 0 0 1 1 1 1 Mitochondrial protein up-regulated during meiosis Tom5 PF10642.9 EAQ86591.1 - 0.065 13.3 0.1 0.18 11.9 0.1 1.7 1 0 0 1 1 1 0 Mitochondrial import receptor subunit or translocase SET PF00856.28 EAQ86592.1 - 0.029 14.7 0.0 0.046 14.1 0.0 1.4 1 0 0 1 1 1 0 SET domain Carn_acyltransf PF00755.20 EAQ86594.1 - 1.7e-176 588.4 0.0 9.4e-143 476.9 0.0 3.0 3 0 0 3 3 3 3 Choline/Carnitine o-acyltransferase Glycophorin_A PF01102.18 EAQ86595.1 - 0.058 13.6 1.7 0.07 13.4 0.1 1.9 2 0 0 2 2 2 0 Glycophorin A TMEM154 PF15102.6 EAQ86595.1 - 0.12 12.3 0.8 0.33 10.9 0.8 1.7 1 0 0 1 1 1 0 TMEM154 protein family DUF515 PF04415.12 EAQ86595.1 - 0.38 9.1 4.4 0.57 8.5 4.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Rad51 PF08423.11 EAQ86596.1 - 1.3e-28 100.0 0.0 8e-26 90.8 0.0 2.1 2 0 0 2 2 2 2 Rad51 AAA_25 PF13481.6 EAQ86596.1 - 2.8e-09 36.8 0.0 5.6e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 EAQ86596.1 - 3.8e-05 23.1 0.0 5.1e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 KaiC RecA PF00154.21 EAQ86596.1 - 0.00011 21.8 0.0 0.00097 18.7 0.0 1.9 2 0 0 2 2 2 1 recA bacterial DNA recombination protein AAA_24 PF13479.6 EAQ86596.1 - 0.071 12.8 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EAQ86596.1 - 0.1 12.8 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Pox_A32 PF04665.12 EAQ86596.1 - 0.28 10.6 0.1 0.46 9.9 0.1 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein RNA_pol_Rpb2_6 PF00562.28 EAQ86597.1 - 4.1e-117 391.6 0.0 5.9e-117 391.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 EAQ86597.1 - 7e-50 169.4 0.0 1.1e-49 168.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 EAQ86597.1 - 5.5e-32 110.0 1.1 1.2e-31 108.9 1.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 EAQ86597.1 - 4.3e-29 101.5 0.0 1.2e-28 100.1 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.13 EAQ86597.1 - 8.1e-21 74.1 0.1 1.8e-20 73.0 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 EAQ86597.1 - 2.3e-20 72.5 0.0 4.8e-20 71.5 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 EAQ86597.1 - 6.8e-11 42.6 0.7 2.1e-10 41.0 0.7 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Pkinase PF00069.25 EAQ86598.1 - 3.9e-10 39.6 0.0 2.5e-09 36.9 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ86598.1 - 0.21 10.8 0.0 0.3 10.3 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase PUF PF00806.19 EAQ86600.1 - 4.7e-61 199.2 11.5 1.1e-07 31.1 0.0 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat CaMBD PF02888.16 EAQ86600.1 - 1.4 9.2 3.4 3.1 8.0 3.4 1.5 1 0 0 1 1 1 0 Calmodulin binding domain Ribosomal_L15e PF00827.17 EAQ86601.1 - 7.9e-90 299.7 9.0 9.6e-90 299.4 9.0 1.0 1 0 0 1 1 1 1 Ribosomal L15 PSP1 PF04468.12 EAQ86603.1 - 1.9e-28 98.5 1.8 3.6e-28 97.7 1.8 1.5 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Nfu_N PF08712.11 EAQ86605.1 - 1.3e-27 95.7 0.0 3.1e-27 94.4 0.0 1.7 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 EAQ86605.1 - 9.5e-27 93.0 0.1 1.6e-26 92.3 0.1 1.4 1 0 0 1 1 1 1 NifU-like domain YojJ PF10372.9 EAQ86605.1 - 0.078 13.1 0.4 0.17 12.0 0.2 1.6 2 0 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus Nuc_deoxyrib_tr PF05014.15 EAQ86606.1 - 0.061 13.3 0.3 0.56 10.2 0.0 2.4 2 0 0 2 2 2 0 Nucleoside 2-deoxyribosyltransferase TFIIA PF03153.13 EAQ86606.1 - 4.3 7.2 9.4 5.5 6.9 9.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RasGEF PF00617.19 EAQ86607.1 - 1.3e-44 152.6 0.2 1.9e-44 152.0 0.2 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 EAQ86607.1 - 5.4e-11 42.7 0.0 1.3e-10 41.5 0.0 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif GTP_EFTU PF00009.27 EAQ86607.1 - 0.00037 20.1 0.0 0.88 9.1 0.0 2.3 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Ras PF00071.22 EAQ86607.1 - 0.0014 18.2 0.0 0.052 13.2 0.0 2.3 2 0 0 2 2 2 1 Ras family MMR_HSR1 PF01926.23 EAQ86607.1 - 0.0089 16.1 0.0 0.017 15.2 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 EAQ86607.1 - 0.01 16.3 0.0 0.028 14.9 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_18 PF13238.6 EAQ86607.1 - 0.033 14.7 0.1 0.25 11.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 EAQ86607.1 - 0.033 14.1 0.0 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase IIGP PF05049.13 EAQ86607.1 - 0.047 12.8 0.0 0.084 11.9 0.0 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_22 PF13401.6 EAQ86607.1 - 0.051 13.8 0.0 0.25 11.6 0.0 2.2 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EAQ86607.1 - 0.055 13.8 0.0 0.25 11.7 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.6 EAQ86607.1 - 0.18 11.6 0.0 0.61 9.9 0.0 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.6 EAQ86607.1 - 0.2 11.3 0.0 0.42 10.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain SLAC1 PF03595.17 EAQ86608.1 - 8.3e-48 163.3 18.6 9.5e-48 163.1 18.6 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Pribosyl_synth PF14572.6 EAQ86609.1 - 1.2e-37 129.7 0.8 5.9e-34 117.7 0.3 2.2 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 EAQ86609.1 - 2.8e-29 101.4 0.0 5.9e-29 100.4 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 EAQ86609.1 - 4.3e-14 52.3 0.2 7.5e-14 51.6 0.2 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EAQ86609.1 - 0.0051 16.3 0.1 0.0093 15.4 0.1 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase RNA_pol_Rpb4 PF03874.16 EAQ86610.1 - 3.9e-25 88.6 0.9 4.8e-25 88.3 0.9 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 PseudoU_synth_1 PF01416.20 EAQ86611.1 - 3.8e-34 117.4 0.0 7.8e-34 116.4 0.0 1.6 1 0 0 1 1 1 1 tRNA pseudouridine synthase Ndc1_Nup PF09531.10 EAQ86611.1 - 0.055 12.1 7.5 0.099 11.3 7.5 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF2076 PF09849.9 EAQ86611.1 - 0.29 11.1 4.3 0.49 10.4 4.3 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Pex14_N PF04695.13 EAQ86611.1 - 5.5 7.6 16.3 12 6.6 16.3 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region FAP PF07174.11 EAQ86611.1 - 5.6 6.3 31.1 4.7 6.6 29.5 1.6 2 0 0 2 2 2 0 Fibronectin-attachment protein (FAP) PIG-H PF10181.9 EAQ86612.1 - 7.8e-27 92.9 0.0 1.3e-26 92.3 0.0 1.4 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component Serglycin PF04360.12 EAQ86612.1 - 0.052 13.5 0.5 0.089 12.7 0.5 1.4 1 0 0 1 1 1 0 Serglycin PUMA PF15826.5 EAQ86615.1 - 0.021 15.0 1.7 0.023 14.9 1.7 1.2 1 0 0 1 1 1 0 Bcl-2-binding component 3, p53 upregulated modulator of apoptosis Snf7 PF03357.21 EAQ86616.1 - 6.5e-23 81.2 2.4 6.5e-23 81.2 2.4 2.0 1 1 0 2 2 2 1 Snf7 DUF3484 PF11983.8 EAQ86616.1 - 2 9.6 6.7 0.73 11.0 3.5 2.0 2 0 0 2 2 2 0 Membrane-attachment and polymerisation-promoting switch Synaphin PF05835.12 EAQ86616.1 - 4.1 7.7 21.8 8.8 6.6 1.0 3.2 2 1 1 3 3 3 0 Synaphin protein Glyco_hydro_43 PF04616.14 EAQ86618.1 - 6.8e-32 110.9 5.9 9.8e-32 110.4 5.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 CTP_transf_like PF01467.26 EAQ86618.1 - 0.00017 21.8 0.0 0.00033 20.9 0.0 1.5 1 0 0 1 1 1 1 Cytidylyltransferase-like GH43_C2 PF17851.1 EAQ86618.1 - 0.017 14.8 0.1 0.044 13.5 0.1 1.6 1 0 0 1 1 1 0 Beta xylosidase C-terminal Concanavalin A-like domain Glyco_hydro_61 PF03443.14 EAQ86619.1 - 2.9e-31 109.0 0.0 3.8e-31 108.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 PARP PF00644.20 EAQ86621.1 - 2.2e-11 43.7 0.0 4e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain UQ_con PF00179.26 EAQ86621.1 - 3.8e-07 29.8 0.0 8.2e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EAQ86621.1 - 0.013 15.2 0.0 0.057 13.1 0.0 2.0 2 0 0 2 2 2 0 Prokaryotic E2 family B COG5 PF10392.9 EAQ86622.1 - 0.0017 18.5 0.4 0.0033 17.6 0.1 1.6 2 0 0 2 2 2 1 Golgi transport complex subunit 5 LD_cluster2 PF18163.1 EAQ86622.1 - 0.079 12.5 0.1 0.14 11.7 0.1 1.3 1 0 0 1 1 1 0 SLOG cluster2 NUDIX PF00293.28 EAQ86623.1 - 5.7e-06 26.4 0.5 1.5e-05 25.1 0.5 1.6 1 1 0 1 1 1 1 NUDIX domain ATE_C PF04377.15 EAQ86624.1 - 5.5e-48 163.0 0.0 9e-48 162.3 0.0 1.4 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 EAQ86624.1 - 1.2e-05 25.7 0.8 2.6e-05 24.5 0.8 1.6 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus Alanine_zipper PF11839.8 EAQ86624.1 - 0.55 10.6 8.3 1 9.8 8.3 1.4 1 0 0 1 1 1 0 Alanine-zipper, major outer membrane lipoprotein Ribosomal_S5_C PF03719.15 EAQ86626.1 - 1.7e-20 72.2 0.0 3.6e-20 71.2 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 EAQ86626.1 - 1.3e-17 63.5 0.5 3e-17 62.3 0.1 1.8 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain DUF676 PF05057.14 EAQ86627.1 - 4.7e-06 26.3 0.0 9.5e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 EAQ86627.1 - 0.00026 20.8 0.0 0.0008 19.2 0.0 1.9 1 0 0 1 1 1 1 PGAP1-like protein AAA_16 PF13191.6 EAQ86627.1 - 0.074 13.4 0.2 0.39 11.1 0.1 2.3 2 1 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 EAQ86627.1 - 0.076 13.3 0.0 0.21 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain Abhydrolase_1 PF00561.20 EAQ86627.1 - 0.096 12.3 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold AAA PF00004.29 EAQ86627.1 - 0.11 13.0 1.5 0.75 10.2 0.6 2.2 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) Torsin PF06309.11 EAQ86627.1 - 0.17 12.0 0.0 0.44 10.6 0.0 1.6 2 0 0 2 2 2 0 Torsin Ank_2 PF12796.7 EAQ86628.1 - 1.4e-30 105.7 0.0 2.8e-10 40.7 0.1 5.0 3 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 EAQ86628.1 - 1.2e-22 79.3 2.4 1.9e-07 31.2 0.9 6.2 5 0 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.6 EAQ86628.1 - 1.7e-21 76.3 0.3 4.4e-08 33.5 0.2 5.6 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAQ86628.1 - 9.2e-21 71.7 0.8 0.0002 21.6 0.1 7.9 8 0 0 8 8 8 5 Ankyrin repeat Ank_5 PF13857.6 EAQ86628.1 - 3.5e-19 68.6 3.3 1.1e-06 28.8 0.2 6.6 4 1 3 7 7 7 5 Ankyrin repeats (many copies) AAA_22 PF13401.6 EAQ86628.1 - 3.4e-06 27.4 0.1 1.6e-05 25.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EAQ86628.1 - 9.6e-06 26.1 0.0 4.4e-05 23.9 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 EAQ86628.1 - 0.00086 19.3 0.1 0.0028 17.6 0.1 1.9 1 1 0 1 1 1 1 NACHT domain AAA_19 PF13245.6 EAQ86628.1 - 0.0019 18.5 0.1 0.0085 16.4 0.1 2.1 2 1 0 2 2 2 1 AAA domain DUF2075 PF09848.9 EAQ86628.1 - 0.051 12.8 0.0 0.14 11.3 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Borrelia_P83 PF05262.11 EAQ86629.1 - 2.4 6.5 25.9 3.3 6.1 25.9 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Pkinase PF00069.25 EAQ86631.1 - 1.4e-65 221.3 0.0 1.9e-65 220.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ86631.1 - 6.2e-25 88.0 0.0 9e-25 87.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAQ86631.1 - 0.0022 17.4 0.1 1.8 7.8 0.0 2.2 2 0 0 2 2 2 2 Kinase-like FOXP-CC PF16159.5 EAQ86632.1 - 0.0008 20.0 4.3 0.41 11.3 0.1 2.4 1 1 1 2 2 2 2 FOXP coiled-coil domain adh_short PF00106.25 EAQ86633.1 - 2.5e-23 82.6 0.0 3.3e-23 82.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EAQ86633.1 - 2e-19 70.1 0.0 2.7e-19 69.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EAQ86633.1 - 2.9e-05 24.0 0.0 4.2e-05 23.5 0.0 1.4 1 1 0 1 1 1 1 KR domain LDcluster4 PF18306.1 EAQ86633.1 - 0.13 11.9 0.2 7.2 6.2 0.0 2.4 2 1 1 3 3 3 0 SLOG cluster4 family DFRP_C PF16543.5 EAQ86634.1 - 3.1e-26 91.7 6.5 3.1e-26 91.7 6.5 3.5 3 0 0 3 3 3 1 DRG Family Regulatory Proteins, Tma46 zf-CCCH PF00642.24 EAQ86634.1 - 3.4e-06 26.8 1.1 3.4e-06 26.8 1.1 2.5 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 EAQ86634.1 - 3.6e-06 27.6 14.0 4.9e-06 27.2 2.0 3.3 2 1 1 3 3 3 2 Torus domain zf_CCCH_4 PF18345.1 EAQ86634.1 - 0.00011 22.1 6.8 0.00011 22.1 6.8 3.2 3 0 0 3 3 3 1 Zinc finger domain zf-CCCH_3 PF15663.5 EAQ86634.1 - 0.001 19.3 0.8 0.042 14.1 0.3 2.6 2 0 0 2 2 2 1 Zinc-finger containing family zf-CCCH_4 PF18044.1 EAQ86634.1 - 0.0016 18.2 11.4 0.011 15.5 2.6 3.3 3 0 0 3 3 3 1 CCCH-type zinc finger zf-CCCH_2 PF14608.6 EAQ86634.1 - 0.063 13.8 14.8 0.42 11.1 5.5 3.0 2 1 0 2 2 2 0 RNA-binding, Nab2-type zinc finger RRM_1 PF00076.22 EAQ86635.1 - 3.1e-14 52.5 0.0 4.9e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 EAQ86635.1 - 0.00061 20.3 1.3 0.00061 20.3 1.3 2.9 2 1 1 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 RRM_occluded PF16842.5 EAQ86635.1 - 0.002 18.0 0.0 0.004 17.0 0.0 1.5 1 0 0 1 1 1 1 Occluded RNA-recognition motif Ribosomal_60s PF00428.19 EAQ86635.1 - 0.34 11.5 15.3 3.7 8.2 0.8 3.4 3 0 0 3 3 3 0 60s Acidic ribosomal protein RNase_PH PF01138.21 EAQ86636.1 - 1.9e-08 34.9 0.0 4.3e-08 33.7 0.0 1.5 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 Ribosomal_60s PF00428.19 EAQ86637.1 - 0.28 11.8 5.8 0.66 10.6 5.8 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein Cytochrom_C PF00034.21 EAQ86638.1 - 5.7e-12 46.6 0.0 8e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 EAQ86638.1 - 9.1e-09 35.5 1.9 3.1e-08 33.8 1.9 1.7 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 EAQ86638.1 - 0.0075 16.0 0.2 0.053 13.2 0.1 2.1 2 0 0 2 2 2 1 Cytochrome c-550 domain AAA PF00004.29 EAQ86639.1 - 1.4e-65 219.7 0.0 1.9e-46 157.8 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EAQ86639.1 - 4.4e-16 58.4 1.9 1.4e-07 31.2 0.0 3.0 3 0 0 3 3 3 2 AAA+ lid domain AAA_2 PF07724.14 EAQ86639.1 - 5e-07 30.0 0.0 0.00025 21.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 EAQ86639.1 - 5.7e-06 26.2 0.0 0.00026 20.8 0.0 2.7 2 1 1 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EAQ86639.1 - 1.1e-05 25.9 0.2 0.017 15.5 0.0 3.4 2 1 2 4 4 3 1 AAA ATPase domain AAA_22 PF13401.6 EAQ86639.1 - 3.5e-05 24.1 0.1 0.012 15.9 0.0 3.4 2 1 2 4 4 3 1 AAA domain AAA_5 PF07728.14 EAQ86639.1 - 4.5e-05 23.5 0.1 0.085 12.9 0.0 2.9 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 EAQ86639.1 - 0.004 17.3 0.0 0.021 15.0 0.0 2.3 3 0 0 3 3 2 1 AAA domain AAA_14 PF13173.6 EAQ86639.1 - 0.0055 16.7 0.0 0.054 13.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 EAQ86639.1 - 0.0062 15.7 0.0 0.014 14.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Zeta_toxin PF06414.12 EAQ86639.1 - 0.02 14.2 0.1 0.12 11.7 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin Vps4_C PF09336.10 EAQ86639.1 - 0.026 14.5 0.0 0.92 9.6 0.0 2.5 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain IstB_IS21 PF01695.17 EAQ86639.1 - 0.033 13.9 0.0 0.066 12.9 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 EAQ86639.1 - 0.036 13.5 0.0 0.079 12.3 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 EAQ86639.1 - 0.037 13.6 0.2 4.1 6.9 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.6 EAQ86639.1 - 0.046 14.3 0.0 0.11 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 EAQ86639.1 - 0.051 12.8 0.0 0.081 12.1 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain RNA_helicase PF00910.22 EAQ86639.1 - 0.053 13.9 0.0 0.1 13.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Rad17 PF03215.15 EAQ86639.1 - 0.075 12.9 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain TIP39 PF14980.6 EAQ86639.1 - 0.093 12.6 0.1 0.27 11.1 0.1 1.7 1 0 0 1 1 1 0 TIP39 peptide Sigma54_activat PF00158.26 EAQ86639.1 - 0.13 12.0 0.0 0.31 10.7 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain ABC_tran PF00005.27 EAQ86639.1 - 0.16 12.5 0.0 0.56 10.7 0.0 1.8 1 1 1 2 2 2 0 ABC transporter Pkinase PF00069.25 EAQ86640.1 - 1.1e-16 61.0 0.0 1.5e-16 60.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ86640.1 - 2.7e-08 33.4 0.0 3.3e-08 33.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EAQ86640.1 - 0.0027 17.7 0.0 0.003 17.5 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EAQ86640.1 - 0.039 13.3 0.0 0.042 13.1 0.0 1.1 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 EAQ86640.1 - 0.11 11.9 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EAQ86640.1 - 0.12 12.0 0.0 0.14 11.7 0.0 1.1 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Mito_carr PF00153.27 EAQ86641.1 - 5.2e-40 135.3 7.8 8.1e-15 54.5 0.3 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein Complex1_LYR PF05347.15 EAQ86642.1 - 0.063 13.3 2.0 0.091 12.8 0.1 2.1 2 0 0 2 2 2 0 Complex 1 protein (LYR family) Sugar_tr PF00083.24 EAQ86643.1 - 2.9e-95 319.8 7.6 3.6e-95 319.5 7.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EAQ86643.1 - 8.8e-27 93.9 45.5 1.2e-24 86.9 20.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EAQ86643.1 - 4.5e-12 45.3 9.2 5.3e-09 35.1 0.0 2.5 3 0 0 3 3 3 2 MFS/sugar transport protein MFS_5 PF05631.14 EAQ86643.1 - 0.003 16.5 1.4 0.0033 16.4 0.1 1.6 2 0 0 2 2 2 1 Sugar-tranasporters, 12 TM GD_AH_C PF04295.13 EAQ86643.1 - 0.095 11.5 0.0 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 D-galactarate dehydratase / Altronate hydrolase, C terminus MFS_3 PF05977.13 EAQ86643.1 - 0.72 8.2 5.4 0.34 9.2 0.8 2.0 2 0 0 2 2 2 0 Transmembrane secretion effector Chs7 PF12271.8 EAQ86644.1 - 5.1e-105 350.9 2.2 6.5e-105 350.6 2.2 1.1 1 0 0 1 1 1 1 Chitin synthase export chaperone DUF347 PF03988.12 EAQ86644.1 - 2.1 8.6 0.0 2.1 8.6 0.0 4.3 5 0 0 5 5 5 0 Repeat of Unknown Function (DUF347) Cytochrom_B561 PF03188.16 EAQ86645.1 - 1.5e-15 57.6 7.2 1.5e-15 57.6 7.2 1.5 1 1 0 1 1 1 1 Eukaryotic cytochrome b561 DUF4079 PF13301.6 EAQ86645.1 - 0.59 10.3 16.5 3.1 8.0 0.5 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF4079) Allantoicase PF03561.15 EAQ86646.1 - 9.3e-92 304.5 0.1 9.4e-47 158.6 0.0 2.1 2 0 0 2 2 2 2 Allantoicase repeat Ank_2 PF12796.7 EAQ86647.1 - 1.3e-13 51.3 0.2 4.9e-13 49.5 0.1 2.1 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAQ86647.1 - 4.1e-12 46.4 0.1 5.2e-07 30.1 0.1 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAQ86647.1 - 2.2e-10 40.6 0.0 6.3e-07 29.6 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EAQ86647.1 - 6e-10 39.1 0.0 0.00078 19.8 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 EAQ86647.1 - 6.8e-06 26.0 0.0 0.23 12.2 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat DIL PF01843.19 EAQ86647.1 - 0.019 15.2 0.0 0.043 14.1 0.0 1.6 1 0 0 1 1 1 0 DIL domain RabGAP-TBC PF00566.18 EAQ86648.1 - 7.9e-32 110.7 0.0 1.4e-31 109.9 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF2722 PF10846.8 EAQ86650.1 - 4.2e-06 26.0 0.0 4.2e-06 26.0 0.0 3.1 2 1 0 3 3 3 2 Protein of unknown function (DUF2722) HATPase_c PF02518.26 EAQ86652.1 - 4.2e-25 88.4 0.1 9.7e-25 87.3 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EAQ86652.1 - 2.3e-20 72.4 0.1 6.8e-20 70.9 0.1 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Response_reg PF00072.24 EAQ86652.1 - 1.5e-19 70.2 0.0 3.6e-19 69.0 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain PAS_3 PF08447.12 EAQ86652.1 - 1.6e-16 60.4 0.4 9.9e-12 45.0 0.4 2.8 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 EAQ86652.1 - 3.3e-09 36.9 0.0 0.00014 22.0 0.0 2.9 3 0 0 3 3 3 2 PAS domain PAS PF00989.25 EAQ86652.1 - 1.2e-08 34.9 0.0 0.0082 16.1 0.0 2.6 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.10 EAQ86652.1 - 1.8e-08 34.6 0.1 1e-06 28.9 0.1 3.0 2 0 0 2 2 2 1 PAS fold PAS_8 PF13188.7 EAQ86652.1 - 0.00044 20.2 0.0 0.26 11.4 0.0 2.7 2 0 0 2 2 2 2 PAS domain Serglycin PF04360.12 EAQ86652.1 - 0.22 11.4 5.2 0.63 10.0 1.1 2.6 2 0 0 2 2 2 0 Serglycin Collagen PF01391.18 EAQ86654.1 - 0.016 14.9 8.0 0.027 14.2 8.0 1.2 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) Ssl1 PF04056.14 EAQ86655.1 - 2.9e-68 229.5 0.0 4e-68 229.0 0.0 1.1 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.12 EAQ86655.1 - 2.8e-17 62.7 8.6 1e-16 60.9 4.9 2.4 2 0 0 2 2 2 1 TFIIH C1-like domain VWA_2 PF13519.6 EAQ86655.1 - 8.4e-14 52.1 0.0 1.7e-13 51.1 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain Zn-ribbon_8 PF09723.10 EAQ86655.1 - 5.1 7.3 10.9 2.6 8.2 5.5 2.4 2 0 0 2 2 2 0 Zinc ribbon domain Glyoxalase PF00903.25 EAQ86656.1 - 2.1e-22 79.7 0.3 1.7e-14 54.1 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 EAQ86656.1 - 4.9e-12 46.1 0.1 0.00014 22.1 0.0 2.4 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 EAQ86656.1 - 1.9e-05 24.9 0.0 0.021 15.0 0.0 2.9 3 0 0 3 3 3 2 Glyoxalase-like domain Glyoxalase_5 PF14696.6 EAQ86656.1 - 0.0025 18.0 0.0 0.006 16.8 0.0 1.6 1 0 0 1 1 1 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal TPR_17 PF13431.6 EAQ86657.1 - 0.13 12.7 0.5 0.96 10.0 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Ribosomal_L27e PF01777.18 EAQ86658.1 - 1.8e-37 127.6 5.7 2.4e-37 127.2 5.7 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 EAQ86658.1 - 0.015 15.2 0.3 0.043 13.8 0.1 1.9 2 0 0 2 2 2 0 KOW motif TPT PF03151.16 EAQ86659.1 - 5.7e-23 81.7 23.2 7.4e-23 81.3 23.2 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family Amino_oxidase PF01593.24 EAQ86660.1 - 1e-07 31.7 0.0 1.7e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EAQ86660.1 - 4.4e-07 30.0 0.1 9.1e-07 29.0 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EAQ86660.1 - 7.7e-05 22.1 0.3 0.057 12.7 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EAQ86660.1 - 0.0056 16.0 0.1 0.0087 15.3 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 EAQ86660.1 - 0.011 15.0 0.2 0.023 13.9 0.2 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EAQ86660.1 - 0.031 13.5 0.6 0.051 12.8 0.1 1.6 2 0 0 2 2 2 0 Thi4 family HI0933_like PF03486.14 EAQ86660.1 - 0.034 12.8 0.1 0.053 12.2 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Lycopene_cycl PF05834.12 EAQ86660.1 - 0.04 13.0 0.1 0.084 11.9 0.1 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein TrkA_N PF02254.18 EAQ86660.1 - 0.078 13.2 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain DUF1344 PF07076.11 EAQ86660.1 - 0.085 12.8 0.2 0.2 11.6 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1344) DAO PF01266.24 EAQ86660.1 - 0.15 11.6 0.3 0.28 10.7 0.1 1.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_oxidored PF12831.7 EAQ86660.1 - 0.17 11.2 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase HATPase_c PF02518.26 EAQ86661.1 - 6.6e-30 103.9 0.4 1.8e-29 102.5 0.1 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EAQ86661.1 - 1.3e-19 70.4 0.1 3.3e-19 69.1 0.1 1.8 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 EAQ86661.1 - 2e-18 66.2 0.5 6.1e-18 64.6 0.5 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF_2 PF13185.6 EAQ86661.1 - 4.8e-11 43.1 0.0 1.8e-10 41.2 0.0 2.0 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 EAQ86661.1 - 1.4e-08 35.5 0.1 1e-07 32.7 0.0 2.4 2 0 0 2 2 2 1 GAF domain AAA_16 PF13191.6 EAQ86661.1 - 9.7e-07 29.3 0.6 2.8e-05 24.6 0.6 3.1 1 1 0 1 1 1 1 AAA ATPase domain GAF_3 PF13492.6 EAQ86661.1 - 1.2e-05 25.7 0.0 3.4e-05 24.2 0.0 1.9 1 0 0 1 1 1 1 GAF domain HATPase_c_3 PF13589.6 EAQ86661.1 - 0.00011 22.1 0.0 0.00028 20.7 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TPR_8 PF13181.6 EAQ86661.1 - 0.016 15.4 0.3 0.45 10.9 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 EAQ86661.1 - 0.5 10.6 3.4 55 4.2 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat GET2 PF08690.10 EAQ86662.1 - 1.2e-67 228.8 0.0 1.5e-67 228.5 0.0 1.0 1 0 0 1 1 1 1 GET complex subunit GET2 DUF3446 PF11928.8 EAQ86662.1 - 0.23 11.8 3.5 1.3 9.4 0.2 2.7 2 1 1 3 3 3 0 Early growth response N-terminal domain SRA1 PF07304.11 EAQ86663.1 - 3.4e-10 39.9 9.3 3.4e-10 39.9 9.3 3.5 3 1 0 3 3 3 1 Steroid receptor RNA activator (SRA1) Sec16_C PF12931.7 EAQ86663.1 - 2.8e-09 37.1 0.0 2.1e-08 34.2 0.0 2.1 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 WD40 PF00400.32 EAQ86663.1 - 7.1e-09 36.2 3.9 0.13 13.2 0.0 6.2 6 0 0 6 6 6 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAQ86663.1 - 0.00079 19.7 0.1 0.32 11.3 0.0 3.1 1 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain DUF3863 PF12979.7 EAQ86663.1 - 0.039 12.8 0.1 0.064 12.1 0.1 1.2 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3863) RRM_1 PF00076.22 EAQ86664.1 - 1.5e-18 66.4 0.0 2.5e-18 65.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EAQ86664.1 - 3.8e-06 26.9 0.0 4.8e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif RRM_5 PF13893.6 EAQ86664.1 - 0.034 13.7 0.0 0.046 13.3 0.0 1.4 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 EAQ86664.1 - 0.038 14.1 0.0 0.065 13.3 0.0 1.4 1 0 0 1 1 1 0 Limkain b1 Nup35_RRM_2 PF14605.6 EAQ86664.1 - 0.069 13.2 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 EAQ86664.1 - 0.1 12.7 0.0 0.69 10.0 0.0 2.0 1 1 0 1 1 1 0 RNA binding motif RRM_occluded PF16842.5 EAQ86664.1 - 0.11 12.4 0.0 0.56 10.1 0.0 1.9 1 1 0 1 1 1 0 Occluded RNA-recognition motif B12D PF06522.11 EAQ86665.1 - 0.01 15.6 0.0 0.014 15.2 0.0 1.3 1 0 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit COX6B PF02297.17 EAQ86666.1 - 2.9e-17 62.7 3.7 3.3e-17 62.5 3.7 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb APOBEC_C PF05240.14 EAQ86666.1 - 0.021 14.7 0.2 0.03 14.3 0.2 1.4 1 0 0 1 1 1 0 APOBEC-like C-terminal domain CX9C PF16860.5 EAQ86666.1 - 0.027 14.5 1.3 0.041 13.9 1.3 1.2 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, ketoacyl-synt PF00109.26 EAQ86666.1 - 0.079 12.5 0.0 0.079 12.5 0.0 1.1 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain Sde2_N_Ubi PF13019.6 EAQ86667.1 - 3.8e-66 222.0 0.3 3.8e-66 222.0 0.3 1.6 2 0 0 2 2 2 1 Silencing defective 2 N-terminal ubiquitin domain Cep57_MT_bd PF06657.13 EAQ86667.1 - 0.27 11.7 1.6 0.65 10.5 1.6 1.6 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 S10_plectin PF03501.15 EAQ86668.1 - 4.7e-39 132.4 0.2 5.7e-39 132.1 0.2 1.1 1 0 0 1 1 1 1 Plectin/S10 domain ADH_N PF08240.12 EAQ86669.1 - 4.2e-24 84.5 0.3 1.5e-23 82.8 0.3 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EAQ86669.1 - 1.2e-12 47.9 0.0 2.1e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EAQ86669.1 - 4.8e-08 34.1 0.0 9.2e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EAQ86669.1 - 3.5e-07 29.9 0.0 7.9e-07 28.8 0.0 1.6 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus EphA2_TM PF14575.6 EAQ86670.1 - 0.34 11.8 0.8 3.6 8.5 0.0 2.4 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain HA2 PF04408.23 EAQ86671.1 - 1.9e-17 63.5 0.1 4.9e-17 62.2 0.1 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EAQ86671.1 - 3.6e-16 59.3 0.0 8.6e-16 58.1 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.6 EAQ86671.1 - 8.2e-05 22.9 0.0 0.0002 21.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain Helicase_C PF00271.31 EAQ86671.1 - 0.00011 22.5 0.0 0.00029 21.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EAQ86671.1 - 0.0005 19.9 0.2 0.0015 18.3 0.2 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_30 PF13604.6 EAQ86671.1 - 0.002 17.9 0.0 0.004 16.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 EAQ86671.1 - 0.03 14.8 0.1 0.085 13.4 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EAQ86671.1 - 0.051 13.3 0.1 0.13 12.0 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain cobW PF02492.19 EAQ86671.1 - 0.14 11.7 0.1 3.6 7.1 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Exotox-A_cataly PF09009.10 EAQ86671.1 - 0.16 11.7 0.0 0.75 9.5 0.0 2.1 2 0 0 2 2 2 0 Exotoxin A catalytic ABC_tran PF00005.27 EAQ86671.1 - 0.34 11.4 1.0 0.93 10.0 0.1 2.0 2 1 0 3 3 3 0 ABC transporter DUF2293 PF10056.9 EAQ86672.1 - 2.4e-33 114.2 0.0 7.9e-33 112.6 0.0 2.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2293) Snf7 PF03357.21 EAQ86673.1 - 1.2e-13 51.1 2.4 1.6e-13 50.6 2.4 1.2 1 0 0 1 1 1 1 Snf7 CUE PF02845.16 EAQ86674.1 - 9.9e-14 50.7 0.0 1.8e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 CUE domain Ank_2 PF12796.7 EAQ86675.1 - 1.1e-29 102.9 1.4 2.1e-10 41.0 0.0 4.1 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAQ86675.1 - 1.1e-25 89.6 3.9 1.2e-07 32.1 0.1 5.7 3 2 2 5 5 5 5 Ankyrin repeats (many copies) SPX PF03105.19 EAQ86675.1 - 5.9e-19 69.3 17.8 5.3e-09 36.5 1.9 3.1 1 1 2 3 3 3 3 SPX domain Ank_3 PF13606.6 EAQ86675.1 - 2e-18 64.6 8.1 0.0018 18.6 0.0 7.7 8 0 0 8 8 8 4 Ankyrin repeat Ank_5 PF13857.6 EAQ86675.1 - 2.5e-15 56.3 8.0 0.003 17.8 0.1 6.5 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 EAQ86675.1 - 1.2e-10 41.3 17.3 0.0031 17.9 0.0 7.6 8 1 1 9 9 9 3 Ankyrin repeat GDPD PF03009.17 EAQ86675.1 - 4.5e-10 39.7 0.0 4.5e-09 36.4 0.0 2.4 2 1 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family RVP PF00077.20 EAQ86675.1 - 0.0077 16.5 0.0 0.019 15.2 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Rsa3 PF14615.6 EAQ86675.1 - 0.29 10.7 1.6 4.8 6.8 0.1 2.8 3 0 0 3 3 3 0 Ribosome-assembly protein 3 Serglycin PF04360.12 EAQ86676.1 - 0.049 13.6 4.4 0.092 12.7 4.4 1.4 1 0 0 1 1 1 0 Serglycin Tetraspanin PF00335.20 EAQ86677.1 - 1.1 9.0 4.9 0.11 12.2 0.3 1.9 2 1 0 2 2 2 0 Tetraspanin family DUF1056 PF06341.11 EAQ86677.1 - 1.9 8.8 9.3 0.11 12.8 1.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1056) Coa1 PF08695.10 EAQ86678.1 - 7.1e-41 138.6 0.0 9.7e-41 138.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 RNA_pol_Rpb2_5 PF04567.17 EAQ86678.1 - 0.14 12.8 0.1 0.32 11.6 0.1 1.5 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 5 Class_IIIsignal PF04021.12 EAQ86678.1 - 0.33 11.0 2.0 0.56 10.3 2.0 1.4 1 0 0 1 1 1 0 Class III signal peptide Ribosomal_L3 PF00297.22 EAQ86679.1 - 2.1e-11 43.4 4.0 5.4e-09 35.5 1.5 2.2 1 1 1 2 2 2 2 Ribosomal protein L3 NFACT-R_1 PF05670.13 EAQ86680.1 - 7e-11 42.7 0.5 1.4e-07 32.2 0.1 2.4 1 1 1 2 2 2 2 NFACT protein RNA binding domain PITH PF06201.13 EAQ86681.1 - 1.9e-39 135.3 0.0 2.3e-39 135.0 0.0 1.1 1 0 0 1 1 1 1 PITH domain Rrn6 PF10214.9 EAQ86682.1 - 9.3e-119 398.3 4.1 2.8e-116 390.1 0.0 2.1 1 1 1 2 2 2 2 RNA polymerase I-specific transcription-initiation factor Spindle_Spc25 PF08234.12 EAQ86683.1 - 2.4e-25 88.5 0.0 6e-25 87.2 0.0 1.7 1 0 0 1 1 1 1 Chromosome segregation protein Spc25 HVSL PF09749.9 EAQ86683.1 - 0.17 11.4 0.8 0.4 10.1 0.3 2.0 2 1 0 2 2 2 0 Uncharacterised conserved protein Atg14 PF10186.9 EAQ86683.1 - 0.86 8.6 7.9 1.5 7.8 7.9 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4407 PF14362.6 EAQ86683.1 - 2 7.7 14.1 2.8 7.2 14.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ADIP PF11559.8 EAQ86683.1 - 3.5 7.7 17.3 1.6 8.8 7.7 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding TMPIT PF07851.13 EAQ86683.1 - 5.9 6.0 7.9 8.8 5.5 7.9 1.2 1 0 0 1 1 1 0 TMPIT-like protein zinc_ribbon_6 PF14599.6 EAQ86684.1 - 1.6e-24 85.6 1.4 1.6e-24 85.6 1.4 3.6 3 2 1 5 5 2 1 Zinc-ribbon zf-CHY PF05495.12 EAQ86684.1 - 3.4e-18 65.9 23.8 3.4e-18 65.9 23.8 3.6 2 1 1 3 3 3 1 CHY zinc finger zf-RING_2 PF13639.6 EAQ86684.1 - 3.4e-08 33.7 5.7 3.4e-08 33.7 5.7 5.2 3 1 1 4 4 2 1 Ring finger domain zf-RING_UBOX PF13445.6 EAQ86684.1 - 3.2e-05 23.9 5.1 3.2e-05 23.9 5.1 3.8 5 0 0 5 5 4 1 RING-type zinc-finger zf-RING_5 PF14634.6 EAQ86684.1 - 0.00017 21.5 6.9 0.00017 21.5 6.9 6.0 5 2 0 6 6 4 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EAQ86684.1 - 0.00028 20.7 6.3 0.00028 20.7 6.3 4.9 6 1 0 6 6 5 1 Zinc finger, C3HC4 type (RING finger) TFIIA PF03153.13 EAQ86684.1 - 0.00043 20.4 12.3 0.00083 19.5 12.3 1.4 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit zf-C3HC4_4 PF15227.6 EAQ86684.1 - 0.0019 18.3 8.0 0.0019 18.3 8.0 5.6 6 1 0 6 6 5 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 EAQ86684.1 - 0.0023 18.2 7.3 0.0023 18.2 7.3 4.8 2 1 2 4 4 2 1 RING-H2 zinc finger domain Nop14 PF04147.12 EAQ86684.1 - 0.38 8.9 21.8 0.58 8.3 21.8 1.3 1 0 0 1 1 1 0 Nop14-like family PPP4R2 PF09184.11 EAQ86684.1 - 0.93 9.0 22.4 1.6 8.3 22.4 1.3 1 0 0 1 1 1 0 PPP4R2 MOZART1 PF12554.8 EAQ86685.1 - 3.5e-24 84.3 0.9 4.3e-24 84.0 0.9 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated DHHA1 PF02272.19 EAQ86685.1 - 0.038 14.4 0.2 0.044 14.2 0.2 1.1 1 0 0 1 1 1 0 DHHA1 domain PI3K_1B_p101 PF10486.9 EAQ86688.1 - 0.46 8.2 3.5 0.59 7.9 3.5 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Ecl1 PF12855.7 EAQ86691.1 - 2e-15 58.4 15.6 2e-15 58.4 15.6 1.9 2 0 0 2 2 2 1 ECL1/2/3 zinc binding proteins zf-MYND PF01753.18 EAQ86691.1 - 0.064 13.4 2.8 0.18 11.9 2.8 1.7 1 0 0 1 1 1 0 MYND finger Pox_A11 PF05061.13 EAQ86693.1 - 0.21 10.9 0.0 0.23 10.7 0.0 1.0 1 0 0 1 1 1 0 Poxvirus A11 Protein His_Phos_1 PF00300.22 EAQ86694.1 - 3.9e-27 95.2 0.0 8.8e-27 94.1 0.0 1.6 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) P5-ATPase PF12409.8 EAQ86694.1 - 0.13 12.4 0.1 0.28 11.3 0.1 1.5 1 0 0 1 1 1 0 P5-type ATPase cation transporter DUF1168 PF06658.12 EAQ86695.1 - 3.9e-37 127.1 5.0 5.9e-37 126.5 5.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) Cpn60_TCP1 PF00118.24 EAQ86696.1 - 1.3e-170 568.3 1.5 1.5e-170 568.1 1.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family BRK PF07533.16 EAQ86696.1 - 0.039 13.6 0.0 0.079 12.6 0.0 1.5 1 0 0 1 1 1 0 BRK domain SKG6 PF08693.10 EAQ86697.1 - 8.7e-09 34.6 2.7 1.7e-08 33.7 2.7 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain TMEM154 PF15102.6 EAQ86697.1 - 0.00014 21.7 2.0 0.00028 20.8 0.0 2.2 1 1 1 2 2 2 1 TMEM154 protein family TMEM51 PF15345.6 EAQ86697.1 - 0.0044 16.9 0.0 0.01 15.7 0.0 1.6 1 0 0 1 1 1 1 Transmembrane protein 51 CD34_antigen PF06365.12 EAQ86697.1 - 0.0086 15.7 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 1 CD34/Podocalyxin family CcmD PF04995.14 EAQ86697.1 - 0.024 14.7 1.8 0.039 14.0 1.8 1.3 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) DUF4448 PF14610.6 EAQ86697.1 - 0.062 13.1 0.0 0.093 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DUF4381 PF14316.6 EAQ86697.1 - 0.091 13.0 0.0 0.15 12.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF2207 PF09972.9 EAQ86697.1 - 0.16 10.7 0.0 0.22 10.3 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) PRCH PF03967.13 EAQ86697.1 - 8.7 6.6 7.5 4.2 7.6 0.0 2.7 3 0 0 3 3 3 0 Photosynthetic reaction centre, H-chain N-terminal region HECT PF00632.25 EAQ86698.1 - 2.5e-19 69.9 0.0 4e-19 69.2 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) C1_1 PF00130.22 EAQ86698.1 - 0.0094 15.8 0.6 0.022 14.6 0.6 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) CRM1_C PF08767.11 EAQ86700.1 - 3.5e-117 391.2 2.3 3.5e-117 391.2 2.3 2.4 3 0 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.12 EAQ86700.1 - 2.2e-41 141.4 10.5 2.8e-41 141.1 6.8 3.2 2 1 0 2 2 2 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 EAQ86700.1 - 1.4e-33 114.3 4.9 5.4e-33 112.5 4.9 2.1 1 0 0 1 1 1 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 EAQ86700.1 - 7.3e-28 96.4 4.6 8.9e-28 96.2 1.2 3.1 3 0 0 3 3 3 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 EAQ86700.1 - 1.2e-19 69.5 1.1 3.1e-19 68.2 1.1 1.8 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat BID PF06393.11 EAQ86700.1 - 0.016 14.7 0.2 0.055 13.0 0.2 1.9 1 0 0 1 1 1 0 BH3 interacting domain (BID) Aminotran_5 PF00266.19 EAQ86701.1 - 5.8e-28 97.9 0.0 7.4e-28 97.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V B12-binding PF02310.19 EAQ86701.1 - 0.12 12.4 0.2 0.48 10.5 0.0 2.1 2 1 0 2 2 2 0 B12 binding domain Metallophos_2 PF12850.7 EAQ86702.1 - 3.1e-11 43.7 0.0 4.3e-11 43.3 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 EAQ86702.1 - 0.077 13.5 0.0 0.15 12.6 0.0 1.5 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase Shugoshin_N PF07558.11 EAQ86703.1 - 6.9e-18 64.2 3.7 1.5e-17 63.2 3.7 1.6 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region Shugoshin_C PF07557.11 EAQ86703.1 - 4.1e-11 42.5 6.3 4.1e-11 42.5 6.3 3.0 2 0 0 2 2 2 1 Shugoshin C terminus GIT_CC PF16559.5 EAQ86703.1 - 0.0074 16.1 0.8 0.017 15.0 0.1 2.0 2 0 0 2 2 2 1 GIT coiled-coil Rho guanine nucleotide exchange factor TMCO5 PF14992.6 EAQ86703.1 - 0.1 12.2 1.4 0.16 11.5 1.4 1.2 1 0 0 1 1 1 0 TMCO5 family DASH_Dad2 PF08654.10 EAQ86704.1 - 1e-14 54.7 6.8 6.4e-12 45.8 3.2 2.1 1 1 1 2 2 2 2 DASH complex subunit Dad2 APG6_N PF17675.1 EAQ86704.1 - 0.023 15.2 0.8 0.028 15.0 0.8 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region Phage_GP20 PF06810.11 EAQ86704.1 - 0.025 14.4 0.3 0.032 14.0 0.3 1.1 1 0 0 1 1 1 0 Phage minor structural protein GP20 SLX9 PF15341.6 EAQ86704.1 - 0.036 14.4 0.3 0.042 14.2 0.3 1.2 1 0 0 1 1 1 0 Ribosome biogenesis protein SLX9 HSCB_C PF07743.13 EAQ86704.1 - 0.081 13.4 1.3 0.13 12.8 1.3 1.3 1 0 0 1 1 1 0 HSCB C-terminal oligomerisation domain COesterase PF00135.28 EAQ86706.1 - 1.2e-55 189.4 0.1 2e-51 175.4 0.1 3.0 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EAQ86706.1 - 1.1e-06 28.7 0.9 7.5e-06 25.9 0.9 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold HLH PF00010.26 EAQ86708.1 - 0.00072 19.5 0.1 0.0022 17.9 0.0 1.8 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain IMS PF00817.20 EAQ86709.1 - 9.2e-33 113.4 0.0 1.4e-32 112.8 0.0 1.2 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 EAQ86709.1 - 4.3e-06 27.4 0.1 1.8e-05 25.4 0.0 2.0 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 EAQ86709.1 - 0.0004 20.5 0.0 0.0011 19.2 0.0 1.7 1 0 0 1 1 1 1 IMS family HHH motif CCSAP PF15748.5 EAQ86710.1 - 1.2 9.3 8.6 2.9 8.0 8.6 1.7 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated C2 PF00168.30 EAQ86711.1 - 1.2e-28 99.4 0.0 2.4e-15 56.7 0.0 2.4 2 0 0 2 2 2 2 C2 domain Spt20 PF12090.8 EAQ86711.1 - 0.42 10.2 15.1 1.9 8.0 10.3 2.4 2 0 0 2 2 2 0 Spt20 family Med3 PF11593.8 EAQ86711.1 - 8 5.5 10.6 0.43 9.7 2.2 2.3 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal GPI2 PF06432.11 EAQ86712.1 - 0.08 12.4 0.0 0.08 12.4 0.0 1.1 1 0 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase CPT PF07931.12 EAQ86713.1 - 0.00076 19.4 0.0 0.0011 18.8 0.0 1.2 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_18 PF13238.6 EAQ86713.1 - 0.00083 19.9 0.0 0.0032 18.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 EAQ86713.1 - 0.0047 17.2 0.0 0.0093 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain PRK PF00485.18 EAQ86713.1 - 0.0086 15.8 0.0 0.019 14.7 0.0 1.7 2 1 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_22 PF13401.6 EAQ86713.1 - 0.15 12.3 0.0 0.26 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 EAQ86713.1 - 0.26 11.0 0.0 9.1 5.9 0.0 2.1 2 0 0 2 2 2 0 Cytidylate kinase CoaE PF01121.20 EAQ86713.1 - 0.27 10.9 0.0 0.39 10.4 0.0 1.2 1 0 0 1 1 1 0 Dephospho-CoA kinase Glyco_hydro_15 PF00723.21 EAQ86714.1 - 2.8e-83 280.2 0.0 3.1e-44 151.5 0.0 2.0 2 0 0 2 2 2 2 Glycosyl hydrolases family 15 CBM_20 PF00686.19 EAQ86714.1 - 2.3e-20 72.3 0.2 5.6e-20 71.0 0.2 1.7 1 0 0 1 1 1 1 Starch binding domain CAP_N PF01213.19 EAQ86714.1 - 0.11 12.0 2.3 0.21 11.0 2.3 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal SART-1 PF03343.13 EAQ86715.1 - 7.9e-183 609.4 53.9 9.1e-183 609.2 53.9 1.0 1 0 0 1 1 1 1 SART-1 family Surface_antigen PF11054.8 EAQ86715.1 - 0.059 13.0 0.1 0.2 11.3 0.1 1.6 1 1 0 1 1 1 0 Sporozoite TA4 surface antigen PTH2 PF01981.16 EAQ86716.1 - 1.9e-45 153.9 0.3 2.5e-45 153.5 0.3 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 BING4CT PF08149.11 EAQ86717.1 - 6.3e-40 134.9 0.0 9e-36 121.5 0.0 3.2 3 0 0 3 3 3 2 BING4CT (NUC141) domain ANAPC4_WD40 PF12894.7 EAQ86717.1 - 1e-07 32.2 0.0 0.89 9.9 0.0 5.5 2 1 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EAQ86717.1 - 0.00019 22.2 0.0 0.013 16.4 0.0 3.6 4 0 0 4 4 4 1 WD domain, G-beta repeat RIBIOP_C PF04950.12 EAQ86718.1 - 3.2e-104 348.5 0.0 5.6e-104 347.7 0.0 1.4 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 EAQ86718.1 - 5.6e-17 61.6 0.0 1.3e-16 60.4 0.0 1.6 1 0 0 1 1 1 1 AARP2CN (NUC121) domain cobW PF02492.19 EAQ86719.1 - 5.4e-29 101.0 0.0 7e-29 100.7 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 EAQ86719.1 - 6.7e-05 22.0 1.0 0.00036 19.6 1.0 1.8 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 EAQ86719.1 - 0.0016 18.5 0.0 0.012 15.7 0.0 2.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 EAQ86719.1 - 0.0072 16.7 0.0 0.0097 16.3 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 EAQ86719.1 - 0.024 14.5 0.0 0.035 13.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system PRK PF00485.18 EAQ86719.1 - 0.042 13.6 0.0 0.081 12.7 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family ATPase_2 PF01637.18 EAQ86719.1 - 0.064 13.2 0.0 0.11 12.4 0.0 1.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea IstB_IS21 PF01695.17 EAQ86719.1 - 0.1 12.3 0.0 0.29 10.8 0.0 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_18 PF13238.6 EAQ86719.1 - 0.11 13.1 0.0 0.18 12.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EAQ86719.1 - 0.12 12.9 0.0 0.14 12.7 0.0 1.2 1 0 0 1 1 1 0 ABC transporter TIP49 PF06068.13 EAQ86719.1 - 0.12 11.6 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain CoaE PF01121.20 EAQ86719.1 - 0.18 11.5 0.0 1.1 8.9 0.0 2.0 2 0 0 2 2 2 0 Dephospho-CoA kinase ATP_bind_1 PF03029.17 EAQ86719.1 - 0.24 11.2 0.1 0.41 10.4 0.1 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein DJ-1_PfpI PF01965.24 EAQ86720.1 - 1.2e-15 57.7 0.0 1.8e-15 57.2 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family GATase PF00117.28 EAQ86720.1 - 0.1 12.4 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Glutamine amidotransferase class-I Chromo PF00385.24 EAQ86721.1 - 1.9e-08 34.1 0.2 4e-08 33.0 0.2 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.6 EAQ86721.1 - 0.059 13.6 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 DUF2486 PF10667.9 EAQ86721.1 - 0.27 11.4 10.6 0.53 10.5 10.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2486) Ras PF00071.22 EAQ86722.1 - 4.8e-38 130.3 0.0 8.8e-38 129.5 0.0 1.3 1 1 0 1 1 1 1 Ras family Roc PF08477.13 EAQ86722.1 - 1.6e-23 83.2 0.2 2.5e-23 82.6 0.2 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAQ86722.1 - 7.6e-08 32.0 0.0 8.7e-08 31.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EAQ86722.1 - 0.011 15.3 0.0 0.012 15.2 0.0 1.1 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain Brix PF04427.18 EAQ86723.1 - 2.1e-32 112.8 0.0 2.6e-32 112.5 0.0 1.1 1 0 0 1 1 1 1 Brix domain F-box-like PF12937.7 EAQ86724.1 - 0.00014 21.7 0.2 0.00037 20.3 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EAQ86724.1 - 0.049 13.5 0.1 0.1 12.5 0.1 1.6 1 0 0 1 1 1 0 F-box domain Hist_deacetyl PF00850.19 EAQ86725.1 - 3.4e-78 263.2 0.0 5.1e-78 262.6 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.9 EAQ86725.1 - 6.2e-49 166.5 0.1 1.8e-47 161.7 0.0 2.2 2 0 0 2 2 2 2 Arb2 domain Gp_dh_C PF02800.20 EAQ86727.1 - 5.4e-74 247.0 0.0 7.9e-74 246.5 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 EAQ86727.1 - 9.8e-39 131.8 0.1 1.9e-38 130.8 0.1 1.5 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 EAQ86727.1 - 0.0038 17.3 0.1 0.011 15.9 0.0 1.8 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.19 EAQ86727.1 - 0.14 11.5 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain tRNA-synt_1d PF00750.19 EAQ86728.1 - 0.0017 17.4 0.0 0.0019 17.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) PAPA-1 PF04795.12 EAQ86731.1 - 1.8e-29 102.4 1.0 1.8e-29 102.4 1.0 4.7 3 1 2 5 5 5 1 PAPA-1-like conserved region Pex14_N PF04695.13 EAQ86732.1 - 1.5e-33 116.7 2.4 1.5e-33 116.7 2.4 3.5 3 1 0 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region HisKA_3 PF07730.13 EAQ86732.1 - 0.28 11.7 4.9 0.46 11.0 0.1 2.9 3 0 0 3 3 3 0 Histidine kinase FTA4 PF13093.6 EAQ86732.1 - 0.65 9.9 7.4 2.1 8.2 3.9 2.5 2 1 0 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DUF4050 PF13259.6 EAQ86733.1 - 2.8e-32 112.5 14.5 5.3e-32 111.6 8.7 3.0 2 1 0 2 2 2 1 Protein of unknown function (DUF4050) SPX PF03105.19 EAQ86734.1 - 3.1e-43 149.2 10.5 2.6e-31 109.9 0.1 3.0 2 1 1 3 3 3 2 SPX domain Na_sulph_symp PF00939.19 EAQ86734.1 - 3e-36 125.5 36.1 5.8e-36 124.5 36.1 1.5 1 1 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 EAQ86734.1 - 4.8e-25 88.4 32.4 4.8e-25 88.4 32.4 2.3 2 1 0 2 2 2 1 Citrate transporter RFX_DNA_binding PF02257.15 EAQ86734.1 - 0.0051 17.4 0.1 0.013 16.1 0.1 1.6 1 0 0 1 1 1 1 RFX DNA-binding domain DUF373 PF04123.13 EAQ86734.1 - 1.3 8.3 15.6 0.66 9.4 5.9 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF373) RTA1 PF04479.13 EAQ86735.1 - 5.5e-67 225.4 9.9 7e-67 225.0 9.9 1.1 1 0 0 1 1 1 1 RTA1 like protein DUF485 PF04341.12 EAQ86735.1 - 1 9.3 7.6 1 9.3 0.3 2.8 2 1 0 2 2 2 0 Protein of unknown function, DUF485 Vps39_1 PF10366.9 EAQ86736.1 - 1.1e-31 109.3 0.0 7.7e-31 106.6 0.0 2.5 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 CNH PF00780.22 EAQ86736.1 - 2.1e-14 53.8 0.0 5.6e-14 52.4 0.0 1.6 1 1 0 1 1 1 1 CNH domain Vps39_2 PF10367.9 EAQ86736.1 - 1.8e-11 44.4 0.0 4.8e-11 43.1 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 TPR_1 PF00515.28 EAQ86736.1 - 0.36 10.7 1.6 13 5.8 0.2 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Gon7 PF08738.10 EAQ86737.1 - 8e-10 38.8 6.9 2.5e-09 37.2 6.9 1.8 1 1 0 1 1 1 1 Gon7 family SURF6 PF04935.12 EAQ86737.1 - 0.00086 19.2 0.1 0.00098 19.0 0.1 1.2 1 0 0 1 1 1 1 Surfeit locus protein 6 Phage_GPL PF05926.11 EAQ86737.1 - 0.023 14.7 0.1 0.031 14.3 0.1 1.2 1 0 0 1 1 1 0 Phage head completion protein (GPL) Mig-14 PF07395.11 EAQ86737.1 - 0.047 13.1 0.0 0.05 13.0 0.0 1.1 1 0 0 1 1 1 0 Mig-14 Serinc PF03348.15 EAQ86737.1 - 0.32 9.9 3.1 0.37 9.7 3.1 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) HbrB PF08539.11 EAQ86738.1 - 4.9e-56 189.4 1.1 1.4e-55 187.9 0.0 2.2 2 0 0 2 2 2 1 HbrB-like Spt20 PF12090.8 EAQ86738.1 - 0.33 10.5 11.0 0.86 9.2 11.0 1.7 1 0 0 1 1 1 0 Spt20 family ANAPC_CDC26 PF10471.9 EAQ86738.1 - 0.69 10.8 13.5 12 6.9 12.0 3.3 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 LIM_bind PF01803.16 EAQ86739.1 - 1e-72 244.6 0.0 1e-72 244.6 0.0 6.3 4 1 2 6 6 6 1 LIM-domain binding protein Atg8 PF02991.16 EAQ86740.1 - 2.6e-51 172.1 0.2 3e-51 171.9 0.2 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 EAQ86740.1 - 4.2e-06 27.1 0.0 5.1e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Coprogen_oxidas PF01218.18 EAQ86741.1 - 1.4e-142 473.8 0.0 1.6e-142 473.6 0.0 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase T6SS_VasE PF05936.12 EAQ86741.1 - 0.048 12.4 0.0 0.075 11.7 0.0 1.2 1 0 0 1 1 1 0 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE MitMem_reg PF13012.6 EAQ86742.1 - 3.8e-37 127.1 0.2 6.5e-37 126.4 0.2 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 EAQ86742.1 - 3.2e-32 111.0 0.0 6.5e-32 110.0 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease tRNA_bind_2 PF13725.6 EAQ86742.1 - 0.036 13.8 2.1 0.053 13.2 2.1 1.2 1 0 0 1 1 1 0 Possible tRNA binding domain S1-like PF14444.6 EAQ86743.1 - 0.079 12.9 0.1 5.2 7.1 0.0 2.3 1 1 1 2 2 2 0 S1-like HOOK PF05622.12 EAQ86744.1 - 3e-16 58.8 35.7 3e-16 58.8 35.7 2.8 2 1 0 2 2 2 1 HOOK protein bZIP_1 PF00170.21 EAQ86744.1 - 0.012 15.7 0.9 0.012 15.7 0.9 9.1 6 2 3 10 10 10 0 bZIP transcription factor ADK PF00406.22 EAQ86745.1 - 2.8e-59 199.5 0.0 3.6e-59 199.2 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EAQ86745.1 - 5.8e-24 85.1 0.2 1.3e-23 84.0 0.1 1.6 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.14 EAQ86745.1 - 3.5e-17 62.1 0.0 1.3e-16 60.3 0.0 2.0 3 0 0 3 3 3 1 Adenylate kinase, active site lid AAA_18 PF13238.6 EAQ86745.1 - 1e-05 26.1 0.0 2.3e-05 25.0 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EAQ86745.1 - 0.0002 21.6 0.0 0.0004 20.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 EAQ86745.1 - 0.15 11.8 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase DUF5315 PF17242.2 EAQ86746.1 - 1.6e-24 85.5 0.5 4.3e-14 52.1 0.3 2.1 2 0 0 2 2 2 2 Disordered region of unknown function (DUF5315) Ribosom_S12_S23 PF00164.25 EAQ86747.1 - 3.8e-51 171.5 0.6 4.7e-51 171.2 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Mito_carr PF00153.27 EAQ86749.1 - 1.7e-66 220.1 5.5 6.2e-25 86.9 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.32 EAQ86749.1 - 6.4e-09 34.7 0.7 4.4e-05 22.7 0.1 3.0 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 EAQ86749.1 - 7.5e-09 35.9 0.1 0.0022 18.4 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EAQ86749.1 - 4.6e-08 32.4 0.6 0.0012 18.6 0.2 3.4 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 EAQ86749.1 - 2.7e-07 29.8 1.3 3.3e-05 23.2 0.4 2.4 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 EAQ86749.1 - 0.00021 21.0 1.2 0.062 13.1 0.2 2.5 2 0 0 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EAQ86749.1 - 0.09 13.1 0.0 2.5 8.4 0.0 2.2 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region PT-VENN PF04829.13 EAQ86749.1 - 1.7 8.7 5.9 23 5.1 0.0 3.2 3 0 0 3 3 3 0 Pre-toxin domain with VENN motif Cyclin_N PF00134.23 EAQ86750.1 - 1.2e-09 38.0 0.9 6.6e-09 35.6 0.4 2.1 1 1 1 2 2 2 1 Cyclin, N-terminal domain TFIIB PF00382.19 EAQ86750.1 - 0.0087 16.1 0.0 0.027 14.5 0.0 1.9 1 0 0 1 1 1 1 Transcription factor TFIIB repeat Cyclin_C_2 PF16899.5 EAQ86750.1 - 0.095 13.1 0.2 0.36 11.2 0.1 2.1 2 0 0 2 2 2 0 Cyclin C-terminal domain AP2 PF00847.20 EAQ86750.1 - 0.14 12.4 0.1 0.14 12.4 0.1 2.2 2 0 0 2 2 2 0 AP2 domain Las1 PF04031.13 EAQ86750.1 - 0.14 12.3 0.7 9 6.4 0.1 2.9 2 1 0 2 2 2 0 Las1-like DUF4766 PF15973.5 EAQ86750.1 - 9 6.9 17.2 16 6.1 17.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4766) BTB PF00651.31 EAQ86752.1 - 0.0019 18.4 0.0 0.0051 17.0 0.0 1.6 2 0 0 2 2 2 1 BTB/POZ domain Peptidase_M17_N PF02789.17 EAQ86752.1 - 0.2 11.6 0.0 0.27 11.1 0.0 1.2 1 0 0 1 1 1 0 Cytosol aminopeptidase family, N-terminal domain DUF4452 PF14618.6 EAQ86753.1 - 4.8e-77 257.6 12.3 5.6e-77 257.4 12.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4452) OGFr_III PF04680.13 EAQ86754.1 - 0.066 13.8 4.7 0.35 11.5 2.9 2.7 2 0 0 2 2 2 0 Opioid growth factor receptor repeat JmjC PF02373.22 EAQ86756.1 - 3e-10 40.5 0.1 8.1e-10 39.1 0.1 1.8 1 1 0 1 1 1 1 JmjC domain, hydroxylase zf-4CXXC_R1 PF10497.9 EAQ86756.1 - 9.2e-10 38.6 9.2 9.2e-10 38.6 9.2 2.8 3 0 0 3 3 3 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Cupin_2 PF07883.11 EAQ86756.1 - 0.053 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Cupin domain UbiA PF01040.18 EAQ86757.1 - 1.4e-42 145.8 21.2 1.8e-42 145.4 21.2 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family RVT_1 PF00078.27 EAQ86760.1 - 1.9e-34 119.1 0.0 1.4e-33 116.3 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 EAQ86760.1 - 4.3e-13 49.2 0.0 1.1e-12 47.8 0.0 1.8 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 EAQ86760.1 - 6e-08 32.5 0.2 2e-07 30.8 0.2 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family AATF-Che1 PF13339.6 EAQ86761.1 - 0.015 16.0 2.9 0.021 15.5 2.9 1.2 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor ZapB PF06005.12 EAQ86761.1 - 0.016 15.6 7.8 0.023 15.1 7.8 1.2 1 0 0 1 1 1 0 Cell division protein ZapB Spc24 PF08286.11 EAQ86761.1 - 0.018 15.3 0.3 0.023 14.9 0.3 1.2 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 GrpE PF01025.19 EAQ86761.1 - 0.038 13.6 7.3 0.046 13.4 7.3 1.1 1 0 0 1 1 1 0 GrpE OmpH PF03938.14 EAQ86761.1 - 0.044 14.1 5.6 0.055 13.8 5.6 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) LMBR1 PF04791.16 EAQ86761.1 - 0.071 12.0 0.7 0.075 11.9 0.7 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein Peptidase_S49_N PF08496.10 EAQ86761.1 - 0.14 12.2 3.6 0.15 12.1 3.6 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal AAA_13 PF13166.6 EAQ86761.1 - 0.16 10.6 5.1 0.19 10.4 5.1 1.0 1 0 0 1 1 1 0 AAA domain Ax_dynein_light PF10211.9 EAQ86761.1 - 0.16 11.9 7.9 0.19 11.6 7.9 1.1 1 0 0 1 1 1 0 Axonemal dynein light chain HAUS5 PF14817.6 EAQ86761.1 - 0.22 10.2 6.9 0.26 10.0 6.9 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 60KD_IMP PF02096.20 EAQ86761.1 - 0.28 11.1 0.7 0.33 10.8 0.7 1.2 1 0 0 1 1 1 0 60Kd inner membrane protein DUF4407 PF14362.6 EAQ86761.1 - 0.28 10.5 2.8 0.3 10.4 2.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Cgr1 PF03879.14 EAQ86761.1 - 0.37 11.2 14.8 0.56 10.6 14.8 1.2 1 0 0 1 1 1 0 Cgr1 family EMC3_TMCO1 PF01956.16 EAQ86761.1 - 0.96 9.2 1.9 1 9.1 1.9 1.1 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Vfa1 PF08432.10 EAQ86761.1 - 3.6 7.9 12.0 14 6.0 12.2 1.6 1 1 1 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Atrophin-1 PF03154.15 EAQ86761.1 - 3.8 5.7 9.8 4 5.6 9.8 1.1 1 0 0 1 1 1 0 Atrophin-1 family DUF1003 PF06210.11 EAQ86761.1 - 4 7.6 10.4 5 7.3 0.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1003) Kdo PF06293.14 EAQ86762.1 - 0.0016 17.9 0.0 0.002 17.5 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 EAQ86762.1 - 0.0018 17.7 0.0 0.0018 17.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 EAQ86762.1 - 0.019 14.9 0.1 0.02 14.8 0.1 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 EAQ86762.1 - 0.064 12.8 0.0 0.077 12.6 0.0 1.1 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF3337 PF11816.8 EAQ86764.1 - 3.1e-56 189.9 0.0 7.3e-56 188.7 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3337) WD40 PF00400.32 EAQ86764.1 - 7.7e-17 61.4 11.6 0.00012 22.8 0.1 5.4 6 0 0 6 6 6 3 WD domain, G-beta repeat Nup160 PF11715.8 EAQ86764.1 - 0.0012 17.6 0.8 0.031 12.9 0.1 2.6 3 0 0 3 3 3 1 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 EAQ86764.1 - 0.0032 17.7 0.1 0.048 14.0 0.0 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Toxin_ToxA PF11584.8 EAQ86764.1 - 0.11 12.4 0.1 0.41 10.7 0.0 1.9 2 0 0 2 2 2 0 Proteinaceous host-selective toxin ToxA Mito_carr PF00153.27 EAQ86765.1 - 1.9e-25 88.6 2.9 2.7e-11 43.2 1.6 3.3 2 1 0 2 2 2 2 Mitochondrial carrier protein Serine_protease PF18405.1 EAQ86765.1 - 0.012 14.8 0.2 0.018 14.2 0.2 1.4 1 0 0 1 1 1 0 Gammaproteobacterial serine protease ATP_bind_3 PF01171.20 EAQ86766.1 - 4.1e-30 104.9 0.0 6.1e-28 97.8 0.0 2.1 2 0 0 2 2 2 2 PP-loop family Asn_synthase PF00733.21 EAQ86766.1 - 0.0038 16.9 0.0 0.0066 16.2 0.0 1.4 1 0 0 1 1 1 1 Asparagine synthase NAD_synthase PF02540.17 EAQ86766.1 - 0.034 13.3 0.0 0.055 12.6 0.0 1.4 1 0 0 1 1 1 0 NAD synthase SNARE PF05739.19 EAQ86767.1 - 0.00021 21.2 0.4 0.00047 20.1 0.4 1.6 1 0 0 1 1 1 1 SNARE domain Mito_fiss_reg PF05308.11 EAQ86767.1 - 0.0021 18.2 3.0 0.0036 17.4 3.0 1.4 1 0 0 1 1 1 1 Mitochondrial fission regulator CorA PF01544.18 EAQ86767.1 - 0.16 11.2 0.1 0.16 11.2 0.1 2.6 2 1 1 3 3 3 0 CorA-like Mg2+ transporter protein DUF3716 PF12511.8 EAQ86768.1 - 9.9e-11 41.5 2.6 1.6e-10 40.9 2.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) Herpes_UL17 PF04559.12 EAQ86769.1 - 0.015 14.2 0.2 0.017 14.0 0.2 1.2 1 0 0 1 1 1 0 Herpesvirus UL17 protein NACHT_sigma PF17106.5 EAQ86770.1 - 0.12 12.5 0.7 1.5 9.0 0.1 2.3 2 0 0 2 2 2 0 Sigma domain on NACHT-NTPases Ank_2 PF12796.7 EAQ86771.1 - 1.7e-40 137.4 0.3 1.4e-11 44.8 0.0 5.5 3 2 2 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.30 EAQ86771.1 - 6.2e-27 92.8 9.6 0.0012 19.2 0.0 8.5 7 1 0 7 7 7 6 Ankyrin repeat Ank_3 PF13606.6 EAQ86771.1 - 2.5e-24 82.7 1.6 0.0049 17.3 0.0 8.0 7 0 0 7 7 7 5 Ankyrin repeat Ank_4 PF13637.6 EAQ86771.1 - 6.2e-24 84.1 0.4 3.6e-06 27.4 0.0 6.4 4 3 3 7 7 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAQ86771.1 - 1.5e-19 69.8 5.6 0.00033 20.9 0.1 6.6 4 2 4 8 8 8 5 Ankyrin repeats (many copies) DDE_1 PF03184.19 EAQ86772.1 - 2.3e-24 86.0 0.1 3.8e-23 82.0 0.1 2.2 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 EAQ86772.1 - 9.8e-10 38.3 0.0 3.1e-09 36.7 0.0 1.9 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.16 EAQ86772.1 - 2.9e-06 26.9 0.0 6.4e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 helix-turn-helix, Psq domain DDE_3 PF13358.6 EAQ86772.1 - 0.001 18.8 0.1 0.0024 17.7 0.1 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease YlqD PF11068.8 EAQ86772.1 - 0.056 13.8 7.5 0.12 12.7 7.5 1.5 1 0 0 1 1 1 0 YlqD protein DUF4200 PF13863.6 EAQ86772.1 - 0.55 10.6 10.2 1.1 9.7 10.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Phage_lysozyme2 PF18013.1 EAQ86772.1 - 1.4 8.9 4.9 0.76 9.8 1.3 2.3 2 1 0 2 2 2 0 Phage tail lysozyme DUF1764 PF08576.10 EAQ86772.1 - 9.3 7.2 8.7 1.2 10.1 4.3 1.8 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) APH PF01636.23 EAQ86773.1 - 2e-18 67.2 0.0 7.1e-18 65.4 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kelch_6 PF13964.6 EAQ86773.1 - 3.1e-13 49.5 4.8 4.1e-06 26.9 0.0 4.5 4 1 1 5 5 5 3 Kelch motif Kelch_1 PF01344.25 EAQ86773.1 - 8.7e-12 44.4 4.9 2.7e-06 26.9 0.1 3.6 3 0 0 3 3 3 2 Kelch motif Kelch_5 PF13854.6 EAQ86773.1 - 1.3e-08 34.6 2.0 0.0028 17.6 0.2 3.7 3 0 0 3 3 3 3 Kelch motif Kelch_2 PF07646.15 EAQ86773.1 - 4.9e-07 29.5 5.5 0.013 15.5 0.6 4.3 4 1 0 4 4 4 2 Kelch motif Kelch_4 PF13418.6 EAQ86773.1 - 5.2e-06 26.4 8.7 0.01 15.9 0.4 4.2 4 1 0 4 4 4 2 Galactose oxidase, central domain Kelch_3 PF13415.6 EAQ86773.1 - 0.0017 18.6 9.9 0.028 14.7 0.4 5.0 6 0 0 6 6 6 1 Galactose oxidase, central domain RNA_polI_A14 PF08203.11 EAQ86773.1 - 0.013 16.2 0.0 0.025 15.3 0.0 1.4 1 0 0 1 1 1 0 Yeast RNA polymerase I subunit RPA14 Choline_kinase PF01633.20 EAQ86773.1 - 0.028 14.0 0.0 0.047 13.3 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Fructosamin_kin PF03881.14 EAQ86773.1 - 0.098 11.8 0.1 0.93 8.6 0.0 2.0 2 0 0 2 2 2 0 Fructosamine kinase PhoD PF09423.10 EAQ86774.1 - 3.8e-113 378.1 0.2 4.8e-113 377.7 0.2 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase PhoD_N PF16655.5 EAQ86774.1 - 2.7e-19 69.5 0.0 6.7e-19 68.2 0.0 1.7 1 0 0 1 1 1 1 PhoD-like phosphatase, N-terminal domain p450 PF00067.22 EAQ86774.1 - 1.8e-08 33.6 0.0 4.1e-08 32.4 0.0 1.5 2 0 0 2 2 2 1 Cytochrome P450 RRM_1 PF00076.22 EAQ86776.1 - 1.5e-18 66.4 0.0 1.9e-18 66.0 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EAQ86776.1 - 0.0091 16.1 0.0 0.013 15.6 0.0 1.3 1 1 0 1 1 1 1 RNA recognition motif Hydrophobin PF01185.18 EAQ86779.1 - 0.022 15.4 13.4 1.8 9.2 14.8 2.0 1 1 1 2 2 2 0 Fungal hydrophobin APH PF01636.23 EAQ86780.1 - 2.5e-20 73.4 0.1 8.2e-20 71.7 0.1 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family MFS_1 PF07690.16 EAQ86781.1 - 2.2e-33 115.6 82.9 2.7e-24 85.8 47.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MS_channel PF00924.18 EAQ86781.1 - 0.36 10.3 5.9 0.7 9.4 5.9 1.5 1 0 0 1 1 1 0 Mechanosensitive ion channel Fungal_trans PF04082.18 EAQ86782.1 - 2.5e-13 49.7 0.0 5e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EAQ86782.1 - 1.6e-08 34.5 11.9 3.9e-08 33.3 11.9 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain APH PF01636.23 EAQ86782.1 - 1.8e-06 28.1 0.9 4.4e-06 26.8 0.3 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Glyco_hydro_61 PF03443.14 EAQ86783.1 - 1.3e-41 142.8 0.2 1.8e-41 142.3 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 SOG2 PF10428.9 EAQ86784.1 - 2.5 7.2 10.2 4.5 6.4 10.2 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein NUDIX PF00293.28 EAQ86785.1 - 6.5e-06 26.2 0.7 7.9e-05 22.7 0.4 2.3 1 1 1 2 2 2 1 NUDIX domain F-box-like PF12937.7 EAQ86788.1 - 4.5e-07 29.7 0.2 1.1e-06 28.4 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EAQ86788.1 - 0.00029 20.6 3.4 0.0021 17.9 3.4 2.3 1 1 0 1 1 1 1 F-box domain F-box-like_2 PF13013.6 EAQ86788.1 - 0.0062 16.5 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 F-box-like domain Ta0938 PF11494.8 EAQ86788.1 - 0.2 11.9 0.0 0.39 11.0 0.0 1.4 1 0 0 1 1 1 0 Ta0938 Peptidase_M41 PF01434.18 EAQ86790.1 - 1.9e-52 177.9 0.1 3.7e-52 176.9 0.1 1.5 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 EAQ86790.1 - 7.7e-43 146.1 0.0 2.2e-42 144.6 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EAQ86790.1 - 1.6e-11 43.8 0.1 3.4e-11 42.8 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 EAQ86790.1 - 7.9e-06 25.9 0.0 2.4e-05 24.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 EAQ86790.1 - 4.9e-05 22.7 0.0 8.2e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_16 PF13191.6 EAQ86790.1 - 0.00034 21.0 2.5 0.00044 20.7 0.1 2.5 2 1 0 2 2 1 1 AAA ATPase domain RuvB_N PF05496.12 EAQ86790.1 - 0.00095 18.9 0.0 0.0019 18.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EAQ86790.1 - 0.0016 18.7 0.2 0.033 14.5 0.2 2.6 2 1 0 2 2 1 1 AAA domain AAA_25 PF13481.6 EAQ86790.1 - 0.0017 18.0 0.4 0.44 10.1 0.2 2.5 1 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EAQ86790.1 - 0.0027 17.8 0.1 0.0091 16.2 0.0 2.0 2 0 0 2 2 1 1 AAA domain IstB_IS21 PF01695.17 EAQ86790.1 - 0.0094 15.7 0.0 0.027 14.2 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 EAQ86790.1 - 0.021 14.2 0.1 0.043 13.2 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ATPase PF06745.13 EAQ86790.1 - 0.033 13.5 0.0 1.4 8.2 0.0 2.3 2 0 0 2 2 2 0 KaiC AAA_2 PF07724.14 EAQ86790.1 - 0.038 14.1 0.0 0.096 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_14 PF13173.6 EAQ86790.1 - 0.07 13.2 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 EAQ86790.1 - 0.077 12.1 0.0 0.16 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_18 PF13238.6 EAQ86790.1 - 0.093 13.3 0.0 0.23 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EAQ86790.1 - 0.11 12.7 0.0 0.25 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EAQ86790.1 - 0.12 11.7 0.7 0.56 9.4 0.4 2.2 1 1 1 2 2 2 0 Zeta toxin TsaE PF02367.17 EAQ86790.1 - 0.13 12.2 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 EAQ86790.1 - 0.14 11.7 0.1 0.41 10.1 0.1 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region PhoH PF02562.16 EAQ86790.1 - 0.17 11.3 0.6 0.43 10.0 0.2 1.8 2 0 0 2 2 2 0 PhoH-like protein Steroid_dh PF02544.16 EAQ86791.1 - 2.2e-20 73.2 1.4 2.4e-19 69.8 1.4 2.1 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 EAQ86791.1 - 0.0024 17.5 0.9 0.0035 16.9 0.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) MINDY_DUB PF04424.13 EAQ86792.1 - 3.1e-24 85.2 0.0 4.8e-24 84.6 0.0 1.3 1 0 0 1 1 1 1 MINDY deubiquitinase DUF1977 PF09320.11 EAQ86793.1 - 5.8e-28 97.2 0.7 1.3e-27 96.1 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1977) DnaJ PF00226.31 EAQ86793.1 - 7.9e-21 74.0 0.1 1.4e-20 73.1 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain Aim19 PF10315.9 EAQ86794.1 - 2.4e-06 27.8 2.7 1.1e-05 25.7 0.1 2.2 1 1 1 2 2 2 1 Altered inheritance of mitochondria protein 19 DUF4536 PF15055.6 EAQ86794.1 - 0.22 11.8 4.6 0.29 11.4 1.3 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4536) Y_phosphatase2 PF03162.13 EAQ86795.1 - 4.7e-45 153.1 0.0 6.6e-45 152.6 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 EAQ86795.1 - 2.3e-09 37.6 0.0 4.5e-09 36.6 0.0 1.4 1 1 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 EAQ86795.1 - 0.005 16.7 0.0 0.0072 16.1 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EAQ86795.1 - 0.0064 16.1 0.0 0.0094 15.5 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase adh_short_C2 PF13561.6 EAQ86796.1 - 2e-56 191.1 3.3 2.4e-56 190.9 3.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EAQ86796.1 - 9.7e-48 162.2 1.0 1.2e-47 161.9 1.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EAQ86796.1 - 3.1e-10 40.3 1.7 1.1e-09 38.5 1.7 1.8 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EAQ86796.1 - 0.00013 21.5 0.1 0.00024 20.7 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Adeno_E3_CR2 PF02439.15 EAQ86797.1 - 0.31 10.8 2.4 0.57 10.0 2.4 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 RabGAP-TBC PF00566.18 EAQ86798.1 - 1.2e-47 162.4 0.0 1.9e-47 161.7 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain F-box-like PF12937.7 EAQ86799.1 - 3.6e-05 23.6 0.0 7.3e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 F-box-like DUF1773 PF08593.10 EAQ86800.1 - 0.51 11.4 2.7 1.3 10.1 2.7 1.7 1 0 0 1 1 1 0 Domain of unknown function Septin PF00735.18 EAQ86801.1 - 5.5e-113 376.9 0.8 6.6e-113 376.7 0.8 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 EAQ86801.1 - 1.4e-07 31.6 0.0 2.5e-07 30.8 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 EAQ86801.1 - 2.1e-06 27.2 0.0 3.8e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 AIG1 family RsgA_GTPase PF03193.16 EAQ86801.1 - 5e-06 26.5 0.1 0.00012 22.0 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 EAQ86801.1 - 3.8e-05 23.3 0.5 0.012 15.2 0.0 2.4 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 EAQ86801.1 - 0.001 19.2 0.4 1.3 9.0 0.2 2.5 1 1 1 2 2 2 2 Dynamin family AAA_22 PF13401.6 EAQ86801.1 - 0.0019 18.5 0.0 0.0046 17.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 EAQ86801.1 - 0.0054 16.3 0.0 0.033 13.7 0.0 2.1 2 0 0 2 2 2 1 P-loop containing dynein motor region NB-ARC PF00931.22 EAQ86801.1 - 0.0055 15.9 0.0 0.009 15.2 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 EAQ86801.1 - 0.0072 16.7 0.0 0.023 15.1 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain ABC_tran PF00005.27 EAQ86801.1 - 0.016 15.7 0.9 0.024 15.1 0.8 1.7 1 1 0 1 1 1 0 ABC transporter Gtr1_RagA PF04670.12 EAQ86801.1 - 0.017 14.5 0.1 0.28 10.5 0.0 2.2 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region G-alpha PF00503.20 EAQ86801.1 - 0.047 12.9 0.6 0.28 10.3 0.1 1.8 1 1 1 2 2 2 0 G-protein alpha subunit FtsK_SpoIIIE PF01580.18 EAQ86801.1 - 0.052 12.9 0.0 0.091 12.1 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Roc PF08477.13 EAQ86801.1 - 0.053 13.8 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Microtub_bd PF16796.5 EAQ86801.1 - 0.058 13.3 0.1 0.53 10.2 0.0 2.2 2 0 0 2 2 2 0 Microtubule binding Ras PF00071.22 EAQ86801.1 - 0.074 12.7 0.1 0.26 10.9 0.0 1.9 2 1 0 2 2 2 0 Ras family AAA_23 PF13476.6 EAQ86801.1 - 0.12 12.8 0.5 0.19 12.2 0.5 1.5 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EAQ86801.1 - 0.17 11.7 0.0 0.33 10.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain WD40 PF00400.32 EAQ86802.1 - 1.4e-14 54.2 8.0 5.1e-06 27.1 0.2 5.9 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAQ86802.1 - 6.1e-14 52.1 0.1 0.0045 17.3 0.0 3.7 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Hira PF07569.11 EAQ86802.1 - 0.00028 20.7 0.1 0.0096 15.7 0.0 2.2 2 0 0 2 2 2 1 TUP1-like enhancer of split PQQ_3 PF13570.6 EAQ86802.1 - 0.0026 18.2 2.9 0.22 12.0 0.1 3.0 2 0 0 2 2 2 1 PQQ-like domain Nup160 PF11715.8 EAQ86802.1 - 0.0038 16.0 0.1 0.044 12.4 0.3 2.1 2 0 0 2 2 2 1 Nucleoporin Nup120/160 eIF2A PF08662.11 EAQ86802.1 - 0.004 17.1 0.0 0.38 10.6 0.0 2.8 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.6 EAQ86802.1 - 0.011 15.0 0.1 6.8 5.9 0.0 3.5 2 1 2 4 4 4 0 Neuroblastoma-amplified sequence, N terminal GATase1_like PF07090.11 EAQ86802.1 - 0.027 13.9 0.0 0.04 13.3 0.0 1.2 1 0 0 1 1 1 0 Putative glutamine amidotransferase Nucleoporin_N PF08801.11 EAQ86802.1 - 0.033 12.9 0.0 0.13 11.0 0.0 1.9 2 1 0 2 2 2 0 Nup133 N terminal like PALB2_WD40 PF16756.5 EAQ86802.1 - 0.063 12.2 0.7 0.22 10.4 0.1 2.0 1 1 1 2 2 2 0 Partner and localizer of BRCA2 WD40 domain DNA_pol_delta_4 PF04081.13 EAQ86803.1 - 4.7e-40 137.0 1.8 4.7e-40 137.0 1.8 1.5 1 1 1 2 2 2 2 DNA polymerase delta, subunit 4 Q_salvage PF10343.9 EAQ86804.1 - 1.9e-117 391.8 0.0 2.3e-117 391.6 0.0 1.1 1 0 0 1 1 1 1 Potential Queuosine, Q, salvage protein family ThiF PF00899.21 EAQ86805.1 - 1.6e-67 227.4 0.0 2.3e-67 226.9 0.0 1.1 1 0 0 1 1 1 1 ThiF family UAE_UbL PF14732.6 EAQ86805.1 - 5.4e-14 52.6 0.0 1.5e-13 51.2 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.9 EAQ86805.1 - 5.2e-06 26.6 1.2 0.0002 21.4 0.4 2.5 1 1 1 2 2 2 1 Ubiquitin-activating enzyme active site NAD_binding_7 PF13241.6 EAQ86805.1 - 0.00012 22.5 0.2 0.00053 20.4 0.0 2.1 2 0 0 2 2 2 1 Putative NAD(P)-binding Shikimate_DH PF01488.20 EAQ86805.1 - 0.022 14.8 0.0 0.051 13.6 0.0 1.7 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 EAQ86805.1 - 0.027 15.0 0.1 0.29 11.7 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Endonuc_Holl PF10107.9 EAQ86805.1 - 0.13 12.1 0.6 0.27 11.1 0.0 1.7 2 0 0 2 2 2 0 Endonuclease related to archaeal Holliday junction resolvase Sacchrp_dh_NADP PF03435.18 EAQ86805.1 - 0.25 11.6 0.7 2 8.7 0.7 2.4 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain adh_short PF00106.25 EAQ86806.1 - 3.5e-33 114.7 0.3 5.4e-33 114.1 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EAQ86806.1 - 2.9e-24 85.9 0.1 3.6e-24 85.6 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 EAQ86806.1 - 3e-08 33.4 0.0 3.9e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 EAQ86806.1 - 1e-07 32.1 1.0 1.5e-07 31.5 1.0 1.2 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 EAQ86806.1 - 5.5e-05 23.4 0.0 0.00011 22.5 0.0 1.5 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Polysacc_synt_2 PF02719.15 EAQ86806.1 - 0.0001 21.5 0.0 0.00013 21.2 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 EAQ86806.1 - 0.00095 18.6 0.0 0.0015 18.0 0.0 1.3 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase F420_oxidored PF03807.17 EAQ86806.1 - 0.004 17.7 0.3 0.0098 16.5 0.3 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent RmlD_sub_bind PF04321.17 EAQ86806.1 - 0.0057 15.8 0.0 0.0079 15.3 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain 3HCDH_N PF02737.18 EAQ86806.1 - 0.01 15.7 0.2 0.017 15.0 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DFP PF04127.15 EAQ86806.1 - 0.04 13.8 0.1 0.073 12.9 0.1 1.6 1 1 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein ApbA PF02558.16 EAQ86806.1 - 0.044 13.4 0.2 0.094 12.4 0.2 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA THF_DHG_CYH_C PF02882.19 EAQ86806.1 - 0.049 12.9 0.0 0.086 12.2 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 2-Hacid_dh_C PF02826.19 EAQ86806.1 - 0.065 12.6 1.3 0.087 12.2 0.2 1.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 EAQ86806.1 - 0.065 13.3 0.2 0.21 11.7 0.0 1.9 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase ADP_PFK_GK PF04587.15 EAQ86806.1 - 0.17 10.5 0.0 0.34 9.4 0.0 1.4 1 1 1 2 2 2 0 ADP-specific Phosphofructokinase/Glucokinase conserved region PAP2 PF01569.21 EAQ86807.1 - 1.2e-15 57.5 2.6 2.8e-15 56.3 2.6 1.6 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 EAQ86807.1 - 0.0013 18.5 3.6 0.0013 18.5 3.6 1.9 2 0 0 2 2 2 1 PAP2 superfamily JmjC PF02373.22 EAQ86808.1 - 1.1e-36 125.7 0.4 1.1e-36 125.7 0.4 1.9 2 0 0 2 2 2 1 JmjC domain, hydroxylase zf-HC5HC2H_2 PF13832.6 EAQ86808.1 - 2.3e-21 76.0 4.1 4.3e-21 75.1 4.1 1.4 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 EAQ86808.1 - 5e-20 71.6 4.5 5e-20 71.6 4.5 1.9 2 0 0 2 2 2 1 PHD-like zinc-binding domain JmjN PF02375.17 EAQ86808.1 - 1.7e-12 47.1 1.5 3.8e-12 45.9 1.5 1.7 1 0 0 1 1 1 1 jmjN domain DUF4440 PF14534.6 EAQ86809.1 - 5e-05 23.6 0.0 7.8e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_2 PF12680.7 EAQ86809.1 - 0.05 14.2 0.0 0.2 12.3 0.0 1.9 1 1 1 2 2 2 0 SnoaL-like domain AA_permease PF00324.21 EAQ86811.1 - 3.3e-101 339.2 33.3 1.1e-49 169.4 2.4 3.0 2 1 0 2 2 2 2 Amino acid permease AA_permease_2 PF13520.6 EAQ86811.1 - 1.2e-22 80.4 33.4 8.6e-09 34.7 5.0 3.2 2 2 1 3 3 3 3 Amino acid permease Na_Ala_symp PF01235.17 EAQ86811.1 - 1 8.6 11.1 2.1 7.6 11.1 1.5 1 0 0 1 1 1 0 Sodium:alanine symporter family RT_RNaseH PF17917.1 EAQ86812.1 - 1.4e-15 57.5 0.0 4.2e-15 55.9 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 EAQ86812.1 - 1.7e-13 50.7 0.0 3e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 EAQ86812.1 - 9e-12 44.9 0.0 1.2e-10 41.3 0.0 2.4 1 1 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 EAQ86812.1 - 2.7e-09 37.3 0.0 6.7e-09 36.0 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 EAQ86812.1 - 1.2e-07 31.8 0.8 6.1e-07 29.5 0.6 2.5 2 0 0 2 2 2 1 Integrase zinc binding domain zf-RVT PF13966.6 EAQ86813.1 - 0.15 12.8 0.0 0.49 11.2 0.0 1.8 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase Clr5 PF14420.6 EAQ86815.1 - 2.1e-07 31.0 0.0 1e-06 28.9 0.0 2.1 2 0 0 2 2 2 1 Clr5 domain Epimerase PF01370.21 EAQ86818.1 - 2.1e-08 33.9 0.0 2.3e-08 33.8 0.0 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EAQ86818.1 - 1.8e-07 30.9 0.0 1.8e-07 30.9 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EAQ86818.1 - 2.9e-06 27.3 0.3 4.2e-06 26.8 0.3 1.3 1 1 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 EAQ86818.1 - 5.8e-06 25.5 0.0 7e-06 25.3 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 EAQ86818.1 - 6.6e-06 25.7 0.1 7.9e-06 25.5 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase F420_oxidored PF03807.17 EAQ86818.1 - 8.3e-06 26.3 0.0 1.1e-05 25.9 0.0 1.3 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_4 PF07993.12 EAQ86818.1 - 9.1e-06 25.0 0.0 1.1e-05 24.8 0.0 1.3 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 EAQ86818.1 - 1.2e-05 24.7 0.0 1.4e-05 24.4 0.0 1.0 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 EAQ86818.1 - 0.00011 22.1 0.0 0.00013 21.9 0.0 1.1 1 0 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 EAQ86818.1 - 0.0069 15.5 0.0 0.0084 15.2 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.13 EAQ86818.1 - 0.0099 15.5 0.1 0.01 15.4 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 EAQ86818.1 - 0.013 15.8 0.0 0.015 15.6 0.0 1.1 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 EAQ86818.1 - 0.11 12.6 0.2 0.18 11.9 0.1 1.4 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase adh_short_C2 PF13561.6 EAQ86818.1 - 0.11 12.0 0.1 0.14 11.7 0.1 1.1 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Ufd2P_core PF10408.9 EAQ86819.1 - 2.2e-217 723.6 7.5 2.6e-217 723.4 7.5 1.0 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 EAQ86819.1 - 0.00042 20.4 0.4 0.0017 18.5 0.4 2.1 1 0 0 1 1 1 1 U-box domain CCDC-167 PF15188.6 EAQ86819.1 - 0.14 12.6 1.2 1 9.7 0.1 2.6 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 MRI PF15325.6 EAQ86819.1 - 2.8 9.1 6.8 13 7.0 6.8 2.2 1 0 0 1 1 1 0 Modulator of retrovirus infection zf-TRAF PF02176.18 EAQ86821.1 - 1.2e-09 38.7 32.0 4.4e-05 24.1 11.2 3.8 1 1 2 3 3 3 3 TRAF-type zinc finger zf-C3HC4_2 PF13923.6 EAQ86821.1 - 1.1e-07 31.5 3.1 1.1e-07 31.5 3.1 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EAQ86821.1 - 7.5e-07 29.4 1.5 7.5e-07 29.4 1.5 3.9 2 1 1 3 3 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 EAQ86821.1 - 8.8e-07 28.7 1.0 8.8e-07 28.7 1.0 3.2 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EAQ86821.1 - 2.2e-06 27.6 3.2 2.2e-06 27.6 3.2 2.8 3 0 0 3 3 3 1 RING-type zinc-finger zf-RING_5 PF14634.6 EAQ86821.1 - 4e-06 26.7 1.4 4e-06 26.7 1.4 2.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.7 EAQ86821.1 - 4.9e-06 26.7 0.7 4.9e-06 26.7 0.7 3.3 3 0 0 3 3 3 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EAQ86821.1 - 2.4e-05 24.1 1.3 2.4e-05 24.1 1.3 4.1 4 1 1 5 5 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EAQ86821.1 - 4.6e-05 23.5 1.6 4.6e-05 23.5 1.6 2.9 2 1 0 2 2 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 EAQ86821.1 - 0.00094 19.0 3.1 0.00094 19.0 3.1 3.4 3 1 0 3 3 2 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 EAQ86821.1 - 0.05 13.4 0.8 0.05 13.4 0.8 3.7 3 2 0 3 3 2 0 RING/Ubox like zinc-binding domain Muted PF14942.6 EAQ86821.1 - 0.095 13.0 0.4 0.19 12.1 0.4 1.4 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein SPO22 PF08631.10 EAQ86822.1 - 3.2e-70 236.7 5.6 4.8e-69 232.9 0.1 3.2 2 1 2 4 4 4 1 Meiosis protein SPO22/ZIP4 like TPR_12 PF13424.6 EAQ86822.1 - 3.4e-06 27.3 3.8 0.29 11.5 0.9 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat PAS PF00989.25 EAQ86822.1 - 0.016 15.2 0.0 0.036 14.1 0.0 1.6 1 0 0 1 1 1 0 PAS fold TPR_2 PF07719.17 EAQ86822.1 - 0.043 13.9 0.1 5.9 7.3 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 EAQ86822.1 - 0.099 12.5 0.3 11 6.0 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Ald_Xan_dh_C2 PF02738.18 EAQ86823.1 - 6.6e-210 698.2 0.0 9.2e-210 697.7 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.21 EAQ86823.1 - 3.8e-47 160.2 0.0 7.6e-47 159.2 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.17 EAQ86823.1 - 4.5e-32 110.3 0.7 2e-31 108.2 0.0 2.4 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Ald_Xan_dh_C PF01315.22 EAQ86823.1 - 1e-30 106.3 0.0 2.3e-30 105.2 0.0 1.6 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.20 EAQ86823.1 - 4e-30 103.7 0.1 8.5e-30 102.6 0.1 1.6 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.27 EAQ86823.1 - 3.6e-08 33.2 0.1 3.6e-08 33.2 0.1 2.4 3 0 0 3 3 3 1 2Fe-2S iron-sulfur cluster binding domain DUF218 PF02698.17 EAQ86823.1 - 0.023 14.7 0.1 0.091 12.8 0.1 1.9 2 0 0 2 2 2 0 DUF218 domain Aldedh PF00171.22 EAQ86824.1 - 5.6e-141 470.2 0.0 6.8e-141 469.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 EAQ86824.1 - 0.00046 19.3 0.5 0.049 12.7 0.0 2.1 2 0 0 2 2 2 2 Acyl-CoA reductase (LuxC) Thiolase_N PF00108.23 EAQ86826.1 - 1.7e-15 57.1 0.3 1.2e-14 54.4 0.0 2.3 2 1 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EAQ86826.1 - 1.4e-08 34.4 1.3 3.4e-08 33.2 0.2 2.2 2 1 1 3 3 3 1 Thiolase, C-terminal domain ACP_syn_III PF08545.10 EAQ86826.1 - 1.8e-06 27.7 1.4 5.3e-05 23.0 0.1 2.8 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.26 EAQ86826.1 - 0.00094 18.8 0.4 0.0025 17.5 0.1 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain SpoVAD PF07451.11 EAQ86826.1 - 0.05 12.3 0.7 0.1 11.3 0.1 1.7 2 0 0 2 2 2 0 Stage V sporulation protein AD (SpoVAD) PMP22_Claudin PF00822.20 EAQ86827.1 - 0.00084 19.3 1.9 0.0038 17.1 0.1 2.1 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin family DUF5316 PF17247.2 EAQ86827.1 - 0.085 12.9 2.2 0.62 10.1 0.5 2.4 2 1 0 2 2 2 0 Family of unknown function (DUF5316) DUF998 PF06197.13 EAQ86827.1 - 0.53 9.9 9.7 1.3 8.6 0.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF998) PPR_2 PF13041.6 EAQ86828.1 - 1.5e-19 69.9 0.2 1.1e-06 28.7 0.1 5.0 4 1 1 5 5 5 4 PPR repeat family PPR PF01535.20 EAQ86828.1 - 8.2e-15 53.9 9.0 1.3e-05 25.1 0.1 6.4 7 0 0 7 7 7 3 PPR repeat PPR_1 PF12854.7 EAQ86828.1 - 1e-12 47.5 5.9 0.00036 20.2 0.2 5.5 5 0 0 5 5 5 3 PPR repeat PPR_3 PF13812.6 EAQ86828.1 - 2.1e-06 27.7 0.5 0.0051 16.9 0.1 3.9 4 1 0 4 4 4 2 Pentatricopeptide repeat domain PPR_long PF17177.4 EAQ86828.1 - 0.00044 19.7 0.1 0.0087 15.4 0.1 2.4 3 0 0 3 3 3 1 Pentacotripeptide-repeat region of PRORP MRP-S25 PF13741.6 EAQ86829.1 - 4.3e-56 190.0 8.3 8e-54 182.6 8.3 2.0 1 1 0 1 1 1 1 Mitochondrial ribosomal protein S25 Alg14 PF08660.11 EAQ86830.1 - 6.7e-41 140.1 0.0 1.1e-40 139.4 0.0 1.3 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like Sec6 PF06046.13 EAQ86831.1 - 1.8e-155 518.6 9.9 2.6e-154 514.8 9.9 2.1 1 1 0 1 1 1 1 Exocyst complex component Sec6 Vps53_N PF04100.12 EAQ86831.1 - 0.00069 18.7 2.0 0.00069 18.7 2.0 1.8 2 0 0 2 2 2 1 Vps53-like, N-terminal DUF3829 PF12889.7 EAQ86831.1 - 0.079 12.4 4.9 0.41 10.1 0.3 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF3829) Vps54_N PF10475.9 EAQ86831.1 - 0.11 11.8 4.9 0.15 11.3 1.1 2.2 1 1 1 2 2 2 0 Vacuolar-sorting protein 54, of GARP complex OmdA PF13376.6 EAQ86831.1 - 1.4 9.0 0.0 1.4 9.0 0.0 3.6 4 0 0 4 4 4 0 Bacteriocin-protection, YdeI or OmpD-Associated Retrotrans_gag PF03732.17 EAQ86831.1 - 2 8.7 5.6 2.6 8.4 0.0 4.2 5 1 0 5 5 5 0 Retrotransposon gag protein THOC7 PF05615.13 EAQ86831.1 - 4.6 7.5 9.5 21 5.4 0.3 3.7 3 1 0 3 3 3 0 Tho complex subunit 7 COX7C PF02935.16 EAQ86832.1 - 9.3e-24 83.5 1.9 1.2e-23 83.2 1.9 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc Pyr_redox_2 PF07992.14 EAQ86833.1 - 2e-60 204.5 3.5 2.3e-60 204.3 3.5 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EAQ86833.1 - 8.3e-18 64.7 6.7 6.5e-17 61.9 0.1 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EAQ86833.1 - 3.4e-17 62.7 0.1 1.1e-16 61.1 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_3 PF13738.6 EAQ86833.1 - 3.2e-16 59.5 0.6 4e-16 59.1 0.6 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EAQ86833.1 - 8.5e-05 21.8 0.0 0.00043 19.5 0.0 2.0 1 1 1 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 EAQ86833.1 - 0.00012 21.0 8.1 0.2 10.3 0.0 3.1 2 1 1 3 3 3 3 HI0933-like protein FAD_oxidored PF12831.7 EAQ86833.1 - 0.0013 18.2 0.1 0.0019 17.6 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 EAQ86833.1 - 0.0062 15.8 0.6 0.012 14.8 0.6 1.4 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 EAQ86833.1 - 0.044 13.4 5.4 0.58 9.7 1.4 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EAQ86833.1 - 0.06 12.4 6.0 1.9 7.5 2.5 2.3 2 0 0 2 2 2 0 FAD binding domain GIDA PF01134.22 EAQ86833.1 - 0.086 11.9 6.7 0.16 11.0 4.5 2.5 3 1 0 3 3 3 0 Glucose inhibited division protein A NAD_binding_8 PF13450.6 EAQ86833.1 - 0.18 12.0 1.1 0.49 10.7 1.1 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Ydc2-catalyt PF09159.10 EAQ86834.1 - 6.6e-64 216.3 0.0 7.9e-64 216.1 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 SAP PF02037.27 EAQ86834.1 - 0.00065 19.4 0.5 0.0016 18.2 0.5 1.6 1 0 0 1 1 1 1 SAP domain 4HBT_3 PF13622.6 EAQ86834.1 - 0.023 15.0 1.8 0.038 14.2 1.8 1.4 1 0 0 1 1 1 0 Thioesterase-like superfamily Pox_A22 PF04848.13 EAQ86834.1 - 0.031 14.4 0.0 15 5.7 0.0 3.2 3 0 0 3 3 3 0 Poxvirus A22 protein DUF3530 PF12048.8 EAQ86834.1 - 0.052 12.9 2.2 0.074 12.5 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) DEAD PF00270.29 EAQ86835.1 - 1.3e-17 64.1 0.0 2.3e-17 63.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EAQ86835.1 - 8.1e-16 58.3 0.0 2.4e-14 53.6 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 EAQ86835.1 - 3e-13 50.3 2.9 6.9e-13 49.1 2.9 1.6 1 0 0 1 1 1 1 RecQ zinc-binding SOG2 PF10428.9 EAQ86836.1 - 5.7e-70 237.0 5.8 9.2e-46 157.1 0.1 4.8 3 2 2 5 5 5 2 RAM signalling pathway protein GCN5L1 PF06320.13 EAQ86836.1 - 1.1e-15 57.8 0.0 3.9e-15 56.0 0.0 1.9 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) LRR_8 PF13855.6 EAQ86836.1 - 4.8e-10 39.1 0.2 1.1e-09 38.0 0.2 1.6 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 EAQ86836.1 - 1.4e-05 25.3 1.1 0.00061 20.1 0.8 2.7 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) DUF812 PF05667.11 EAQ86836.1 - 0.033 13.1 0.0 0.054 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF2408 PF10303.9 EAQ86836.1 - 0.033 14.7 0.3 0.11 13.1 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) Steroid_dh PF02544.16 EAQ86837.1 - 3.3e-21 75.8 0.2 6.8e-21 74.8 0.0 1.6 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.13 EAQ86837.1 - 0.001 19.4 0.4 0.0057 17.0 0.4 2.2 1 1 0 1 1 1 1 Phospholipid methyltransferase DUF1295 PF06966.12 EAQ86837.1 - 0.0012 18.4 0.2 0.0017 17.9 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) TPR_10 PF13374.6 EAQ86838.1 - 1.2e-52 174.4 19.0 6.1e-12 45.0 0.1 6.8 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_12 PF13424.6 EAQ86838.1 - 5.1e-46 154.9 12.9 3.6e-15 56.0 1.0 4.9 1 1 2 4 4 4 4 Tetratricopeptide repeat TPR_7 PF13176.6 EAQ86838.1 - 2.4e-19 67.9 14.8 0.00056 19.7 0.2 6.9 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.17 EAQ86838.1 - 3.3e-16 58.0 9.4 0.00067 19.6 0.1 6.0 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_1 PF00515.28 EAQ86838.1 - 4.1e-15 54.9 3.7 0.0088 15.8 0.1 5.5 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_MalT PF17874.1 EAQ86838.1 - 9.7e-15 54.8 11.6 4.4e-07 29.6 1.6 2.8 1 1 1 2 2 2 2 MalT-like TPR region TPR_4 PF07721.14 EAQ86838.1 - 1.3e-12 47.0 0.5 0.56 11.0 0.0 6.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 EAQ86838.1 - 7.5e-12 45.7 5.7 0.019 15.6 0.1 5.5 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 EAQ86838.1 - 3e-10 39.5 3.5 0.55 10.6 0.1 6.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 EAQ86838.1 - 6.1e-08 32.5 0.0 1 9.9 0.0 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 EAQ86838.1 - 1.9e-06 28.3 4.2 0.16 12.5 0.3 4.7 2 2 2 4 4 4 2 Tetratricopeptide repeat AAA_22 PF13401.6 EAQ86838.1 - 0.00083 19.6 0.0 0.0024 18.1 0.0 1.8 2 0 0 2 2 1 1 AAA domain TPR_6 PF13174.6 EAQ86838.1 - 0.0014 19.1 12.3 6 7.7 0.0 6.3 7 0 0 7 7 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 EAQ86838.1 - 0.0058 17.3 10.7 23 6.2 0.1 6.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_3 PF07720.12 EAQ86838.1 - 0.043 13.8 2.2 8.8 6.4 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_5 PF12688.7 EAQ86838.1 - 0.046 14.0 1.3 1.9 8.8 0.1 3.1 3 0 0 3 3 3 0 Tetratrico peptide repeat TPR_11 PF13414.6 EAQ86838.1 - 0.43 10.3 8.0 5.8 6.7 0.1 4.2 4 0 0 4 4 4 0 TPR repeat PNP_UDP_1 PF01048.20 EAQ86839.1 - 0.0007 18.9 0.0 0.0014 18.0 0.0 1.6 1 0 0 1 1 1 1 Phosphorylase superfamily rRNA_proc-arch PF13234.6 EAQ86840.1 - 1.8e-34 119.9 0.0 4.3e-34 118.7 0.0 1.6 1 0 0 1 1 1 1 rRNA-processing arch domain DEAD PF00270.29 EAQ86840.1 - 4e-18 65.8 0.0 8e-18 64.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EAQ86840.1 - 2.4e-07 31.1 0.1 8e-07 29.4 0.1 1.9 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EAQ86840.1 - 2.2e-05 24.5 0.0 7.5e-05 22.8 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit T2SSE PF00437.20 EAQ86840.1 - 0.075 12.1 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein ATPase_2 PF01637.18 EAQ86840.1 - 0.077 12.9 0.2 0.28 11.1 0.0 1.9 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Ras PF00071.22 EAQ86841.1 - 2.9e-15 56.2 0.0 4.1e-15 55.8 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAQ86841.1 - 5.3e-10 39.6 0.0 8.1e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 EAQ86841.1 - 2.2e-06 27.7 0.0 6.2e-06 26.3 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.10 EAQ86841.1 - 3.8e-06 26.5 0.0 6.5e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Dynamin_N PF00350.23 EAQ86841.1 - 0.0011 19.0 0.2 0.0071 16.4 0.2 2.0 1 1 1 2 2 2 1 Dynamin family TsaE PF02367.17 EAQ86841.1 - 0.0099 15.9 0.0 0.017 15.1 0.0 1.3 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE FeoB_N PF02421.18 EAQ86841.1 - 0.012 15.1 0.1 0.02 14.4 0.1 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B cobW PF02492.19 EAQ86841.1 - 0.013 15.1 0.1 0.19 11.3 0.1 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Arf PF00025.21 EAQ86841.1 - 0.018 14.5 0.0 0.032 13.7 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family ABC_tran PF00005.27 EAQ86841.1 - 0.028 14.9 0.0 0.054 14.0 0.0 1.4 1 0 0 1 1 1 0 ABC transporter RsgA_GTPase PF03193.16 EAQ86841.1 - 0.035 14.0 0.1 0.071 13.0 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase DLIC PF05783.11 EAQ86841.1 - 0.036 12.9 0.0 0.059 12.2 0.0 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) AAA_24 PF13479.6 EAQ86841.1 - 0.042 13.6 0.1 0.58 9.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain IIGP PF05049.13 EAQ86841.1 - 0.07 12.2 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) PduV-EutP PF10662.9 EAQ86841.1 - 0.087 12.6 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation GTP_EFTU PF00009.27 EAQ86841.1 - 0.11 12.1 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_28 PF13521.6 EAQ86841.1 - 0.11 12.7 0.0 0.36 11.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain Septin PF00735.18 EAQ86841.1 - 0.27 10.5 0.0 0.46 9.7 0.0 1.3 1 0 0 1 1 1 0 Septin Aminotran_1_2 PF00155.21 EAQ86842.1 - 1.7e-64 218.3 0.0 1.9e-64 218.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 EAQ86842.1 - 0.00057 19.3 0.0 0.0011 18.4 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 EAQ86842.1 - 0.0014 17.9 0.0 0.0023 17.2 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 EAQ86842.1 - 0.0018 16.9 0.0 0.0034 16.0 0.0 1.4 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 EAQ86842.1 - 0.0054 15.7 0.0 0.011 14.8 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V HMA PF00403.26 EAQ86845.1 - 6.4e-17 61.7 0.9 1.1e-16 60.9 0.9 1.4 1 0 0 1 1 1 1 Heavy-metal-associated domain Fer2_BFD PF04324.15 EAQ86845.1 - 0.03 14.7 0.1 0.18 12.2 0.0 2.1 2 0 0 2 2 2 0 BFD-like [2Fe-2S] binding domain Tcf25 PF04910.14 EAQ86846.1 - 6.9e-54 183.2 0.3 9.2e-54 182.8 0.3 1.1 1 0 0 1 1 1 1 Transcriptional repressor TCF25 BioT2 PF15368.6 EAQ86846.1 - 0.085 12.8 0.4 0.16 12.0 0.4 1.3 1 0 0 1 1 1 0 Spermatogenesis family BioT2 NST1 PF13945.6 EAQ86846.1 - 0.44 10.6 6.2 0.77 9.8 6.2 1.3 1 0 0 1 1 1 0 Salt tolerance down-regulator DUF3807 PF12720.7 EAQ86846.1 - 1.6 9.0 8.9 3 8.1 8.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Herpes_DNAp_acc PF04929.12 EAQ86846.1 - 3.4 6.5 7.4 5.2 5.9 7.4 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor XAP5 PF04921.14 EAQ86846.1 - 3.7 7.3 7.7 6.5 6.5 7.7 1.3 1 0 0 1 1 1 0 XAP5, circadian clock regulator LSM14 PF12701.7 EAQ86848.1 - 5.5e-31 106.5 0.0 8.8e-31 105.8 0.0 1.3 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.10 EAQ86848.1 - 1.8e-18 67.3 1.5 1.8e-18 67.3 1.5 2.0 2 0 0 2 2 2 1 FDF domain SM-ATX PF14438.6 EAQ86848.1 - 2.8e-06 27.4 0.0 5.4e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Ataxin 2 SM domain TFIIA PF03153.13 EAQ86848.1 - 6.9 6.6 20.8 10 6.0 20.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DENN PF02141.21 EAQ86849.1 - 3.2e-39 134.8 0.1 5.8e-39 134.0 0.1 1.5 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 EAQ86849.1 - 8.6e-07 29.6 0.0 2.8e-06 28.0 0.0 2.0 1 0 0 1 1 1 1 uDENN domain IFT57 PF10498.9 EAQ86849.1 - 0.00072 18.6 3.5 0.00072 18.6 3.5 1.9 1 1 1 2 2 2 1 Intra-flagellar transport protein 57 MCC-bdg_PDZ PF10506.9 EAQ86849.1 - 0.014 15.4 1.3 0.014 15.4 1.3 2.7 3 0 0 3 3 3 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Dfp1_Him1_M PF08630.10 EAQ86849.1 - 0.021 15.0 1.2 2.5 8.3 1.9 2.4 2 0 0 2 2 2 0 Dfp1/Him1, central region Elongin_A PF06881.11 EAQ86849.1 - 0.057 14.0 6.1 0.057 14.0 3.9 2.1 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A DNA_binding_1 PF01035.20 EAQ86850.1 - 2.5e-12 46.8 0.0 4.5e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain GRP PF07172.11 EAQ86851.1 - 0.42 11.3 18.4 0.085 13.6 14.0 2.2 2 0 0 2 2 2 0 Glycine rich protein family AAA_23 PF13476.6 EAQ86851.1 - 2.7 8.4 9.8 5.1 7.6 9.8 1.4 1 0 0 1 1 1 0 AAA domain FAM76 PF16046.5 EAQ86851.1 - 8 5.7 10.8 16 4.7 10.8 1.4 1 0 0 1 1 1 0 FAM76 protein CBFD_NFYB_HMF PF00808.23 EAQ86852.1 - 0.0021 18.3 0.3 0.52 10.6 0.0 2.3 2 1 0 2 2 2 2 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Prefoldin_2 PF01920.20 EAQ86853.1 - 1.5e-08 34.6 3.6 1.5e-08 34.6 3.6 1.3 2 0 0 2 2 2 1 Prefoldin subunit DASH_Dad1 PF08649.10 EAQ86854.1 - 4.2e-24 84.5 4.0 9.5e-19 67.4 2.0 2.2 2 0 0 2 2 2 2 DASH complex subunit Dad1 Ras PF00071.22 EAQ86855.1 - 3.3e-48 163.4 0.0 4e-48 163.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAQ86855.1 - 3.2e-20 72.5 0.0 5.3e-20 71.8 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAQ86855.1 - 1.5e-05 24.5 0.0 3.7e-05 23.3 0.0 1.7 1 1 0 1 1 1 1 ADP-ribosylation factor family AAA_7 PF12775.7 EAQ86855.1 - 0.076 12.5 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Skp1_POZ PF03931.15 EAQ86856.1 - 7.6e-10 38.8 0.0 1.1e-09 38.3 0.0 1.2 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain DBR1 PF05011.13 EAQ86857.1 - 7.1e-46 156.1 0.0 2e-45 154.7 0.0 1.7 2 0 0 2 2 2 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.28 EAQ86857.1 - 8.3e-07 29.7 0.6 1.3e-06 29.1 0.6 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Abhydrolase_6 PF12697.7 EAQ86858.1 - 5.8e-19 69.6 1.2 5.8e-19 69.6 1.2 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EAQ86858.1 - 4.2e-18 65.9 0.5 1.2e-17 64.4 0.5 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EAQ86858.1 - 2.1e-15 56.7 0.0 2.9e-15 56.2 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 EAQ86858.1 - 9.8e-05 22.3 0.1 0.00019 21.4 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EAQ86858.1 - 0.0002 20.9 0.2 0.00057 19.4 0.1 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family Thioesterase PF00975.20 EAQ86858.1 - 0.00074 19.7 0.1 0.0014 18.8 0.1 1.4 1 0 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.13 EAQ86858.1 - 0.0026 17.5 0.0 0.0046 16.7 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein DUF3089 PF11288.8 EAQ86858.1 - 0.0042 16.7 0.0 0.007 15.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3089) Abhydrolase_5 PF12695.7 EAQ86858.1 - 0.0072 16.1 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.25 EAQ86858.1 - 0.008 16.0 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) AXE1 PF05448.12 EAQ86858.1 - 0.0081 14.9 0.5 0.56 8.8 0.5 2.3 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) DUF2974 PF11187.8 EAQ86858.1 - 0.024 14.2 0.0 0.056 13.0 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) LIDHydrolase PF10230.9 EAQ86858.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.5 1 1 0 1 1 1 0 Lipid-droplet associated hydrolase DUF3530 PF12048.8 EAQ86858.1 - 0.22 10.9 0.0 0.32 10.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) DMRT-like PF15791.5 EAQ86860.1 - 0.11 12.9 0.2 0.11 12.9 0.2 1.9 2 0 0 2 2 2 0 Doublesex-and mab-3-related transcription factor C1 and C2 V_ATPase_I PF01496.19 EAQ86864.1 - 0.085 10.8 6.7 0.097 10.6 6.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RR_TM4-6 PF06459.12 EAQ86864.1 - 0.09 12.6 9.3 0.12 12.2 9.3 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TFIIA PF03153.13 EAQ86864.1 - 0.13 12.2 40.0 0.17 11.8 40.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit eIF-3_zeta PF05091.12 EAQ86864.1 - 0.15 11.0 13.6 0.2 10.6 13.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) HSP70 PF00012.20 EAQ86864.1 - 0.6 8.2 5.7 0.73 7.9 5.7 1.0 1 0 0 1 1 1 0 Hsp70 protein DUF1980 PF09323.10 EAQ86864.1 - 0.67 9.8 2.5 0.93 9.4 2.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Ndc1_Nup PF09531.10 EAQ86864.1 - 0.85 8.2 7.3 1 7.9 7.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CLN3 PF02487.17 EAQ86864.1 - 5.6 5.9 8.9 7 5.6 8.9 1.1 1 0 0 1 1 1 0 CLN3 protein UPF0560 PF10577.9 EAQ86864.1 - 7.4 4.9 24.0 10 4.5 24.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Aminopep PF10023.9 EAQ86864.1 - 9.4 5.5 19.4 13 5.0 19.4 1.1 1 0 0 1 1 1 0 Putative aminopeptidase EF-hand_6 PF13405.6 EAQ86865.1 - 5.1e-09 35.4 1.2 0.00031 20.5 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 EAQ86865.1 - 1.5e-08 34.9 0.6 1.5e-08 34.9 0.6 1.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 EAQ86865.1 - 4e-06 26.0 2.1 1.8e-05 23.9 0.2 2.3 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.6 EAQ86865.1 - 6e-06 25.5 0.1 6e-06 25.5 0.1 2.0 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 EAQ86865.1 - 0.001 18.8 0.6 0.0019 18.0 0.0 1.7 2 0 0 2 2 2 1 EF-hand domain pair DUF2470 PF10615.9 EAQ86866.1 - 4e-27 94.7 0.0 8e-27 93.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) Met_10 PF02475.16 EAQ86866.1 - 2.4e-05 24.2 0.0 0.00036 20.4 0.0 2.1 2 0 0 2 2 2 1 Met-10+ like-protein MTS PF05175.14 EAQ86866.1 - 0.025 14.2 0.0 0.044 13.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain tRNA_U5-meth_tr PF05958.11 EAQ86866.1 - 0.069 12.1 0.0 0.1 11.6 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Fungal_trans PF04082.18 EAQ86867.1 - 1.7e-14 53.5 1.4 2.6e-14 52.9 1.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EAQ86867.1 - 1.3e-07 31.6 7.4 2.5e-07 30.7 7.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ilm1 PF10311.9 EAQ86867.1 - 0.15 11.7 0.0 0.3 10.7 0.0 1.4 1 0 0 1 1 1 0 Increased loss of mitochondrial DNA protein 1 Phosphoesterase PF04185.14 EAQ86868.1 - 1.3e-15 57.4 0.3 1.3e-14 54.2 0.3 2.3 1 1 0 1 1 1 1 Phosphoesterase family Pirin_C PF05726.13 EAQ86869.1 - 2.9e-23 82.2 0.1 5.1e-23 81.4 0.1 1.4 1 0 0 1 1 1 1 Pirin C-terminal cupin domain Pirin PF02678.16 EAQ86869.1 - 5.6e-14 52.0 0.0 1.2e-13 50.9 0.0 1.6 1 0 0 1 1 1 1 Pirin Cupin_2 PF07883.11 EAQ86869.1 - 0.38 10.5 1.8 1.4 8.7 0.1 2.6 3 1 0 3 3 3 0 Cupin domain zf-HIT PF04438.16 EAQ86870.1 - 1.1e-10 41.1 9.6 1.6e-10 40.6 9.6 1.2 1 0 0 1 1 1 1 HIT zinc finger zf-MYND PF01753.18 EAQ86870.1 - 3.5 7.8 8.4 7.2 6.8 8.4 1.5 1 0 0 1 1 1 0 MYND finger ubiquitin PF00240.23 EAQ86872.1 - 0.0021 17.8 0.0 0.003 17.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family YukD PF08817.10 EAQ86872.1 - 0.03 15.0 0.0 0.052 14.2 0.0 1.4 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD Dsh_C PF12316.8 EAQ86872.1 - 0.083 13.3 3.3 0.12 12.8 3.3 1.2 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal DUF1923 PF09083.10 EAQ86872.1 - 0.23 11.2 0.1 0.5 10.1 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1923) Presenilin PF01080.17 EAQ86872.1 - 0.72 8.6 1.6 0.7 8.6 1.6 1.1 1 0 0 1 1 1 0 Presenilin Nop PF01798.18 EAQ86873.1 - 9.9e-62 208.4 9.7 2.5e-56 190.7 0.4 3.0 2 1 1 3 3 3 2 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 EAQ86873.1 - 4.6e-20 71.8 0.7 4.6e-20 71.8 0.7 2.5 2 0 0 2 2 2 1 NOP5NT (NUC127) domain DUF1062 PF06353.12 EAQ86873.1 - 0.064 14.1 0.7 0.21 12.4 0.7 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1062) TSGP1 PF07771.11 EAQ86873.1 - 4.3 7.5 24.6 8.6 6.5 6.8 2.6 2 0 0 2 2 2 0 Tick salivary peptide group 1 Coilin_N PF15862.5 EAQ86873.1 - 6 6.7 27.7 0.25 11.1 3.8 2.3 2 0 0 2 2 2 0 Coilin N-terminus vATP-synt_AC39 PF01992.16 EAQ86874.1 - 2e-94 316.9 0.0 2.3e-94 316.7 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Ribosomal_S15 PF00312.22 EAQ86875.1 - 2e-21 76.0 1.9 3.8e-21 75.1 0.1 2.4 3 0 0 3 3 3 1 Ribosomal protein S15 LMBR1 PF04791.16 EAQ86875.1 - 0.035 13.0 0.0 0.039 12.9 0.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Ribosomal_S2 PF00318.20 EAQ86876.1 - 6e-27 94.3 0.1 4e-15 55.6 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 EAQ86876.1 - 0.00084 20.7 13.1 0.0016 19.7 13.1 1.5 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus RasGEF PF00617.19 EAQ86877.1 - 1.4e-46 158.9 0.1 2.1e-46 158.4 0.1 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 EAQ86877.1 - 1.1e-13 51.3 0.2 2.3e-13 50.3 0.2 1.5 1 0 0 1 1 1 1 RasGEF N-terminal motif F-box-like PF12937.7 EAQ86878.1 - 0.014 15.3 0.1 0.042 13.7 0.1 1.9 1 0 0 1 1 1 0 F-box-like Ank_2 PF12796.7 EAQ86879.1 - 1.7e-59 198.3 10.2 2.6e-17 63.2 0.3 5.5 3 1 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAQ86879.1 - 2.6e-45 152.2 3.2 1.9e-07 31.5 0.0 9.3 2 2 7 9 9 9 8 Ankyrin repeats (many copies) Ank PF00023.30 EAQ86879.1 - 9.4e-42 139.7 19.1 0.00072 19.9 0.1 10.6 10 0 0 10 10 10 8 Ankyrin repeat Ank_5 PF13857.6 EAQ86879.1 - 9.3e-36 121.4 0.4 9.9e-06 25.7 0.0 8.7 2 1 7 9 9 9 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAQ86879.1 - 2e-26 89.1 0.6 0.68 10.7 0.0 10.0 9 0 0 9 9 9 6 Ankyrin repeat NACHT PF05729.12 EAQ86879.1 - 1.4e-08 34.9 0.9 2.2e-08 34.2 0.1 1.8 2 0 0 2 2 2 1 NACHT domain PNP_UDP_1 PF01048.20 EAQ86879.1 - 2.2e-08 33.6 0.2 1.8e-07 30.7 0.1 2.6 3 1 0 3 3 3 1 Phosphorylase superfamily AAA_16 PF13191.6 EAQ86879.1 - 1.9e-05 25.1 1.5 4.9e-05 23.8 0.5 2.2 2 0 0 2 2 1 1 AAA ATPase domain AAA_22 PF13401.6 EAQ86879.1 - 0.0027 18.0 0.0 0.0067 16.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 EAQ86879.1 - 0.011 15.8 0.0 0.99 9.4 0.0 3.2 2 1 0 2 2 2 0 AAA domain NB-ARC PF00931.22 EAQ86879.1 - 0.025 13.8 0.0 0.075 12.2 0.0 1.8 1 0 0 1 1 1 0 NB-ARC domain UPF0184 PF03670.13 EAQ86879.1 - 0.051 14.0 0.1 0.19 12.1 0.1 1.9 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) Focal_AT PF03623.13 EAQ86879.1 - 0.053 13.5 0.8 0.34 10.9 0.1 2.6 2 0 0 2 2 2 0 Focal adhesion targeting region YajC PF02699.15 EAQ86879.1 - 0.068 13.1 3.4 9.7 6.2 0.0 4.6 3 1 3 6 6 6 0 Preprotein translocase subunit Bac_A_amyl_C PF18612.1 EAQ86879.1 - 0.071 12.9 0.3 26 4.7 0.0 3.8 4 0 0 4 4 3 0 Bacterial Alpha amylase C-terminal domain ATPase_2 PF01637.18 EAQ86879.1 - 0.077 12.9 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea DERM PF14704.6 EAQ86879.1 - 0.24 11.9 0.9 0.65 10.5 0.3 1.9 2 0 0 2 2 2 0 Dermatopontin Amidinotransf PF02274.17 EAQ86879.1 - 0.36 9.9 1.7 2.8 6.9 0.1 2.9 1 1 0 2 2 2 0 Amidinotransferase Endosulfine PF04667.17 EAQ86882.1 - 0.041 14.0 1.1 0.13 12.4 0.2 2.1 2 0 0 2 2 2 0 cAMP-regulated phosphoprotein/endosulfine conserved region KxDL PF10241.9 EAQ86883.1 - 9.8e-31 105.9 2.4 1.4e-30 105.4 2.4 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein DHHA1 PF02272.19 EAQ86883.1 - 0.0013 19.1 0.2 0.42 11.0 0.0 2.4 3 0 0 3 3 3 2 DHHA1 domain OrfB_IS605 PF01385.19 EAQ86883.1 - 5.3 7.3 8.9 2.2 8.5 2.1 2.5 1 1 1 2 2 2 0 Probable transposase DDE_1 PF03184.19 EAQ86884.1 - 1.3e-35 122.6 0.1 1.4e-34 119.3 0.0 2.3 2 1 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 EAQ86884.1 - 5.5e-13 48.7 0.1 1.3e-12 47.5 0.1 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.16 EAQ86884.1 - 4.3e-08 32.8 0.0 7.4e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_23 PF13384.6 EAQ86884.1 - 0.00023 20.8 0.1 0.00087 19.0 0.0 2.1 2 0 0 2 2 2 1 Homeodomain-like domain PT PF04886.12 EAQ86884.1 - 0.21 11.1 5.7 0.49 10.0 5.7 1.6 1 0 0 1 1 1 0 PT repeat Aldedh PF00171.22 EAQ86886.1 - 4.5e-185 615.6 0.0 5e-185 615.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family TRF PF08558.10 EAQ86887.1 - 2.3e-55 187.8 0.0 3.7e-55 187.1 0.0 1.3 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.31 EAQ86887.1 - 2.8e-05 24.2 0.0 6e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAQ86887.1 - 0.054 13.8 0.2 0.14 12.4 0.0 1.8 2 0 0 2 2 2 0 Myb-like DNA-binding domain ketoacyl-synt PF00109.26 EAQ86888.1 - 1.4e-73 247.6 0.3 1.4e-73 247.6 0.3 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain SAT PF16073.5 EAQ86888.1 - 9e-52 176.2 0.2 6.7e-51 173.3 0.0 2.4 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Acyl_transf_1 PF00698.21 EAQ86888.1 - 3.1e-41 141.9 0.0 5e-41 141.3 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Fungal_trans PF04082.18 EAQ86888.1 - 5.6e-16 58.4 0.1 1.3e-15 57.2 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ketoacyl-synt_C PF02801.22 EAQ86888.1 - 1.5e-15 57.3 1.0 4.4e-15 55.7 0.1 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.6 EAQ86888.1 - 2.9e-13 49.7 0.1 5.5e-13 48.8 0.1 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 EAQ86888.1 - 2.1e-09 37.8 0.0 5.6e-09 36.5 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Zn_clus PF00172.18 EAQ86888.1 - 2.3e-07 30.8 13.7 4.3e-07 29.9 13.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Thioesterase PF00975.20 EAQ86888.1 - 1.7e-06 28.4 0.5 5.1e-06 26.8 0.1 2.1 2 0 0 2 2 2 1 Thioesterase domain Thiolase_N PF00108.23 EAQ86888.1 - 0.011 15.2 0.8 0.025 14.0 0.8 1.5 1 0 0 1 1 1 0 Thiolase, N-terminal domain MFS_1 PF07690.16 EAQ86889.1 - 7.8e-38 130.3 44.9 7.8e-38 130.3 44.9 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EAQ86889.1 - 1.4e-09 37.3 12.3 1.4e-09 37.3 12.3 2.1 2 1 0 2 2 2 1 Sugar (and other) transporter Zn_clus PF00172.18 EAQ86890.1 - 4.4e-08 33.1 7.5 9.1e-08 32.1 7.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Spt5_N PF11942.8 EAQ86890.1 - 0.85 10.6 4.6 2 9.4 0.4 2.9 3 0 0 3 3 3 0 Spt5 transcription elongation factor, acidic N-terminal DUF4611 PF15387.6 EAQ86890.1 - 2.2 8.6 5.2 8.6 6.7 0.7 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) DUF3246 PF11596.8 EAQ86890.1 - 5.4 6.4 12.6 1.4 8.3 2.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) Trp_halogenase PF04820.14 EAQ86891.1 - 4.1e-26 91.8 0.2 9.1e-12 44.6 0.3 2.5 1 1 1 2 2 2 2 Tryptophan halogenase Methyltransf_2 PF00891.18 EAQ86891.1 - 1.7e-23 83.0 0.2 3.6e-23 82.0 0.2 1.5 1 0 0 1 1 1 1 O-methyltransferase domain FAD_binding_3 PF01494.19 EAQ86891.1 - 2e-15 56.9 1.2 4.3e-15 55.8 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 EAQ86891.1 - 0.00014 21.4 0.5 0.00038 19.9 0.5 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EAQ86891.1 - 0.0003 21.0 2.3 0.00035 20.7 0.0 2.4 3 0 0 3 3 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EAQ86891.1 - 0.00036 19.9 0.0 0.0014 17.9 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EAQ86891.1 - 0.00039 19.6 0.0 0.00069 18.8 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.14 EAQ86891.1 - 0.001 17.9 0.1 0.0015 17.3 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein Methyltransf_19 PF04672.12 EAQ86891.1 - 0.14 11.6 0.1 0.25 10.8 0.1 1.3 1 0 0 1 1 1 0 S-adenosyl methyltransferase Dimerisation PF08100.11 EAQ86891.1 - 0.17 11.9 0.0 1.9 8.6 0.0 2.7 2 0 0 2 2 2 0 Dimerisation domain DUF4027 PF13219.6 EAQ86891.1 - 0.22 11.4 0.3 0.55 10.1 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4027) Ank_4 PF13637.6 EAQ86892.1 - 2e-56 187.7 7.1 1.8e-12 47.5 0.1 10.0 3 2 7 10 10 10 8 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAQ86892.1 - 6.5e-55 183.7 0.1 2e-16 60.4 0.0 5.6 2 2 2 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.30 EAQ86892.1 - 8.6e-41 136.6 3.5 1.6e-07 31.5 0.0 8.9 8 1 1 9 9 9 6 Ankyrin repeat Ank_5 PF13857.6 EAQ86892.1 - 1e-35 121.3 10.5 3.2e-09 36.9 0.1 9.6 5 3 5 10 10 10 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAQ86892.1 - 3.4e-34 113.0 5.3 5.5e-05 23.3 0.0 9.9 10 1 1 11 11 10 6 Ankyrin repeat zf-C2H2 PF00096.26 EAQ86892.1 - 6.4e-06 26.3 6.1 0.017 15.6 0.7 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 EAQ86892.1 - 0.023 14.5 6.4 0.21 11.4 0.8 2.7 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 EAQ86892.1 - 0.034 15.0 6.6 0.69 10.9 0.4 3.0 2 1 0 2 2 2 0 C2H2-type zinc finger DUF2520 PF10728.9 EAQ86892.1 - 0.11 12.2 0.9 3.4 7.5 0.1 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF2520) zf-C2HE PF16278.5 EAQ86892.1 - 0.11 12.9 1.3 0.14 12.6 0.2 1.7 1 1 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger zf-BED PF02892.15 EAQ86892.1 - 0.32 11.0 4.9 0.69 10.0 4.9 1.5 1 0 0 1 1 1 0 BED zinc finger zf-H2C2_2 PF13465.6 EAQ86892.1 - 1.8 9.1 6.1 7.4 7.2 2.2 2.7 2 0 0 2 2 2 0 Zinc-finger double domain GAGA PF09237.11 EAQ86892.1 - 4.9 7.0 6.3 1.1 9.1 0.4 2.5 2 0 0 2 2 2 0 GAGA factor Thioesterase PF00975.20 EAQ86893.1 - 1.2e-19 71.3 0.1 3.5e-19 69.8 0.1 1.7 2 0 0 2 2 2 1 Thioesterase domain PP-binding PF00550.25 EAQ86893.1 - 1.9e-10 41.0 0.1 3e-10 40.3 0.1 1.3 1 0 0 1 1 1 1 Phosphopantetheine attachment site Abhydrolase_3 PF07859.13 EAQ86893.1 - 0.03 14.2 0.1 0.7 9.7 0.0 2.1 1 1 1 2 2 2 0 alpha/beta hydrolase fold Mito_fiss_reg PF05308.11 EAQ86893.1 - 0.22 11.5 7.3 0.35 10.9 7.3 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator ketoacyl-synt PF00109.26 EAQ86894.1 - 3e-76 256.4 0.1 4.9e-76 255.6 0.1 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.6 EAQ86894.1 - 4.6e-56 190.3 0.4 8.5e-56 189.4 0.4 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 EAQ86894.1 - 4.1e-55 186.5 0.9 4.1e-55 186.5 0.9 2.4 2 0 0 2 2 2 1 KR domain Ketoacyl-synt_C PF02801.22 EAQ86894.1 - 5.3e-30 103.8 6.5 4.5e-21 75.1 0.4 3.3 2 1 1 3 3 3 2 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N_2 PF13602.6 EAQ86894.1 - 1.3e-19 71.5 0.5 8.6e-19 68.9 0.0 2.7 3 0 0 3 3 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EAQ86894.1 - 1.7e-17 63.7 3.7 8e-17 61.4 0.1 3.8 4 0 0 4 4 4 1 Zinc-binding dehydrogenase KAsynt_C_assoc PF16197.5 EAQ86894.1 - 3.4e-16 59.7 2.0 2.2e-12 47.4 0.0 3.6 2 1 1 3 3 3 2 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 EAQ86894.1 - 2.6e-12 46.6 3.0 2e-10 40.4 0.2 3.5 3 0 0 3 3 3 1 short chain dehydrogenase Acyl_transf_1 PF00698.21 EAQ86894.1 - 1.1e-09 38.2 0.0 2.5e-08 33.8 0.0 2.7 2 1 1 3 3 3 1 Acyl transferase domain Thiolase_N PF00108.23 EAQ86894.1 - 1.5e-05 24.5 0.0 3.3e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain adh_short_C2 PF13561.6 EAQ86894.1 - 8.7e-05 22.2 0.4 8.7e-05 22.2 0.4 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase PP-binding PF00550.25 EAQ86894.1 - 0.0059 16.9 0.0 0.018 15.4 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Ank_4 PF13637.6 EAQ86895.1 - 1.4e-14 54.3 0.0 6.3e-05 23.5 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAQ86895.1 - 1.4e-13 51.2 0.0 2e-08 34.7 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAQ86895.1 - 3.4e-10 40.0 0.1 3.8e-06 27.1 0.0 2.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EAQ86895.1 - 2.6e-08 34.0 0.1 0.0017 18.8 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 EAQ86895.1 - 1e-07 31.6 0.0 0.53 11.0 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat GSDH PF07995.11 EAQ86896.1 - 1.2e-118 396.2 0.1 1.4e-118 396.0 0.1 1.0 1 0 0 1 1 1 1 Glucose / Sorbosone dehydrogenase NHL PF01436.21 EAQ86896.1 - 0.041 13.9 0.0 0.39 10.8 0.0 2.7 3 0 0 3 3 3 0 NHL repeat Reg_prop PF07494.11 EAQ86896.1 - 0.081 13.2 4.9 4.3 7.9 0.0 4.4 4 0 0 4 4 4 0 Two component regulator propeller cobW PF02492.19 EAQ86898.1 - 9.1e-27 93.8 3.9 3.3e-16 59.4 0.3 2.2 1 1 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 EAQ86898.1 - 1.5e-18 66.5 1.0 1.2e-13 50.8 0.1 3.0 3 0 0 3 3 3 2 Cobalamin synthesis protein cobW C-terminal domain NOA36 PF06524.12 EAQ86898.1 - 0.0035 16.7 5.0 0.0054 16.1 5.0 1.2 1 0 0 1 1 1 1 NOA36 protein TFIIA PF03153.13 EAQ86898.1 - 0.042 13.8 7.9 0.062 13.3 7.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CobT PF06213.12 EAQ86898.1 - 0.068 12.6 10.0 0.14 11.5 10.0 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT SDA1 PF05285.12 EAQ86898.1 - 0.15 11.5 8.9 0.24 10.8 8.9 1.2 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 EAQ86898.1 - 0.17 10.1 4.2 0.24 9.7 4.2 1.1 1 0 0 1 1 1 0 CDC45-like protein MeaB PF03308.16 EAQ86898.1 - 0.18 10.7 0.5 8.3 5.3 0.1 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Sigma70_ner PF04546.13 EAQ86898.1 - 0.34 10.8 4.1 0.83 9.5 4.1 1.6 1 0 0 1 1 1 0 Sigma-70, non-essential region Cwf_Cwc_15 PF04889.12 EAQ86898.1 - 3.2 7.4 17.0 5.3 6.7 17.0 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 EAQ86898.1 - 4.3 5.4 12.7 6.3 4.9 12.7 1.1 1 0 0 1 1 1 0 Nop14-like family YL1 PF05764.13 EAQ86898.1 - 6 6.9 11.6 11 6.1 11.6 1.3 1 0 0 1 1 1 0 YL1 nuclear protein DNA_pol_phi PF04931.13 EAQ86898.1 - 8.9 4.3 20.8 13 3.7 20.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi SnoaL PF07366.12 EAQ86900.1 - 0.074 12.9 0.2 3.1 7.6 0.1 2.1 1 1 1 2 2 2 0 SnoaL-like polyketide cyclase Band_7 PF01145.25 EAQ86901.1 - 9.7e-18 64.8 2.3 1.7e-15 57.5 0.4 2.4 1 1 1 2 2 2 2 SPFH domain / Band 7 family Band_7_1 PF13421.6 EAQ86901.1 - 0.033 13.9 0.2 0.053 13.2 0.2 1.4 1 0 0 1 1 1 0 SPFH domain-Band 7 family Kinesin_assoc PF16183.5 EAQ86901.1 - 0.46 10.6 2.4 0.45 10.6 0.9 1.7 2 0 0 2 2 2 0 Kinesin-associated DEAD PF00270.29 EAQ86902.1 - 3.5e-38 131.1 0.0 7e-38 130.1 0.0 1.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EAQ86902.1 - 9.1e-23 80.7 0.0 2.2e-22 79.5 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EAQ86902.1 - 3.8e-20 71.9 0.1 7.6e-20 70.9 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 EAQ86902.1 - 5.7e-05 23.2 0.0 0.00013 22.0 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EAQ86902.1 - 0.0023 17.2 0.5 0.05 12.8 0.0 2.2 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase IHABP4_N PF16174.5 EAQ86902.1 - 1 10.0 14.5 1.7 9.2 14.5 1.3 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal zf-C2H2_9 PF16293.5 EAQ86903.1 - 0.09 12.6 0.0 0.32 10.8 0.0 1.9 1 0 0 1 1 1 0 C2H2 type zinc-finger (1 copy) YabA PF06156.13 EAQ86905.1 - 0.021 15.4 17.9 0.55 10.9 7.3 4.0 1 1 3 4 4 4 0 Initiation control protein YabA DUF2019 PF09450.10 EAQ86905.1 - 0.058 13.4 2.5 0.064 13.2 0.6 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF2019) Allexi_40kDa PF05549.11 EAQ86905.1 - 0.29 10.6 1.8 0.46 10.0 1.4 1.5 1 1 0 1 1 1 0 Allexivirus 40kDa protein Cbl_N PF02262.16 EAQ86905.1 - 0.33 11.0 6.5 2 8.4 0.2 3.1 2 1 1 3 3 3 0 CBL proto-oncogene N-terminal domain 1 TMPIT PF07851.13 EAQ86905.1 - 3.4 6.8 5.0 4.5 6.4 5.0 1.4 1 0 0 1 1 1 0 TMPIT-like protein FapA PF03961.13 EAQ86905.1 - 4.9 5.7 6.4 3.2 6.3 4.6 1.4 1 1 0 1 1 1 0 Flagellar Assembly Protein A HALZ PF02183.18 EAQ86905.1 - 8.4 6.7 21.7 0.32 11.2 0.7 4.6 4 1 1 5 5 5 0 Homeobox associated leucine zipper Hormone_1 PF00103.20 EAQ86906.1 - 0.32 10.7 5.5 0.28 10.9 2.0 2.1 1 1 1 2 2 2 0 Somatotropin hormone family Sec34 PF04136.15 EAQ86906.1 - 0.62 9.9 4.3 1.2 9.0 4.3 1.5 1 0 0 1 1 1 0 Sec34-like family RasGAP_C PF03836.15 EAQ86906.1 - 0.67 10.1 11.8 1.4 9.1 11.7 1.6 1 1 0 1 1 1 0 RasGAP C-terminus DUF5339 PF17274.2 EAQ86906.1 - 1.6 9.6 6.2 3.9 8.4 6.2 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5339) YabA PF06156.13 EAQ86906.1 - 2.1 9.0 12.1 2.9 8.6 5.8 2.6 1 1 0 2 2 2 0 Initiation control protein YabA KxDL PF10241.9 EAQ86906.1 - 2.2 8.6 15.2 0.34 11.2 1.6 2.6 2 1 1 3 3 2 0 Uncharacterized conserved protein SKA1 PF07160.12 EAQ86906.1 - 4.7 7.0 19.6 0.9 9.3 15.8 1.6 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 DUF3763 PF12592.8 EAQ86906.1 - 5.5 7.1 5.5 1.5 8.9 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3763) Prominin PF05478.11 EAQ86906.1 - 6.4 4.6 4.6 8.8 4.1 4.6 1.1 1 0 0 1 1 1 0 Prominin CCDC-167 PF15188.6 EAQ86906.1 - 6.4 7.2 17.3 0.026 14.9 6.4 2.2 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 GREB1 PF15782.5 EAQ86906.1 - 8.6 3.3 17.3 12 2.9 17.3 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer FlaC_arch PF05377.11 EAQ86906.1 - 9.3 6.7 6.0 16 6.0 3.1 2.2 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Smg4_UPF3 PF03467.15 EAQ86907.1 - 5.5e-52 176.3 0.1 5.5e-52 176.3 0.1 2.4 3 0 0 3 3 3 1 Smg-4/UPF3 family AbiJ_NTD3 PF18860.1 EAQ86907.1 - 0.2 11.2 0.0 0.38 10.3 0.0 1.3 1 0 0 1 1 1 0 AbiJ N-terminal domain 3 Metallophos PF00149.28 EAQ86908.1 - 9.6e-32 111.1 0.0 2.4e-27 96.8 0.0 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Glyco_hydro_65N PF03636.15 EAQ86908.1 - 0.034 13.8 0.0 0.052 13.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain STPPase_N PF16891.5 EAQ86908.1 - 0.1 13.1 0.1 0.23 12.0 0.1 1.5 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Thr_synth_N PF14821.6 EAQ86909.1 - 1.9e-27 95.3 0.0 4.6e-27 94.0 0.0 1.7 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.25 EAQ86909.1 - 2.7e-19 69.7 0.0 1.9e-18 66.9 0.0 1.9 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DSPc PF00782.20 EAQ86910.1 - 1.5e-08 34.6 0.0 0.00011 22.1 0.0 2.7 2 1 0 2 2 2 2 Dual specificity phosphatase, catalytic domain ANAPC4_WD40 PF12894.7 EAQ86911.1 - 0.012 15.9 0.0 1.6 9.0 0.0 3.5 2 2 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Adaptin_N PF01602.20 EAQ86912.1 - 1.4e-113 380.2 0.8 2e-113 379.7 0.8 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 EAQ86912.1 - 2.2e-47 159.9 0.0 5.2e-47 158.7 0.0 1.7 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.20 EAQ86912.1 - 5.7e-17 62.0 0.0 1.1e-16 61.2 0.0 1.4 1 0 0 1 1 1 1 Adaptin C-terminal domain Methyltransf_11 PF08241.12 EAQ86913.1 - 1.4e-10 41.7 0.0 3e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EAQ86913.1 - 7.9e-08 32.9 0.0 1.6e-07 32.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EAQ86913.1 - 2.8e-07 30.5 0.0 5e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAQ86913.1 - 4.4e-07 30.5 0.0 1.3e-06 29.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAQ86913.1 - 6.3e-05 22.8 0.0 0.00015 21.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EAQ86913.1 - 0.029 13.7 0.0 0.044 13.1 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family P16-Arc PF04699.14 EAQ86914.1 - 1.3e-50 171.7 0.0 1.5e-50 171.5 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) PIF1 PF05970.14 EAQ86918.1 - 7.8e-15 54.9 0.0 1.2e-14 54.3 0.0 1.3 1 0 0 1 1 1 1 PIF1-like helicase UvrD_C_2 PF13538.6 EAQ86918.1 - 0.0098 15.7 0.0 0.034 14.0 0.0 2.0 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 EAQ86918.1 - 0.013 15.2 0.0 0.084 12.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 EAQ86918.1 - 0.17 12.2 0.0 0.31 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain TAF4 PF05236.14 EAQ86919.1 - 9.1e-22 78.1 12.3 7.7e-18 65.2 2.9 2.7 3 0 0 3 3 3 2 Transcription initiation factor TFIID component TAF4 family CPSF73-100_C PF11718.8 EAQ86920.1 - 1.3e-87 292.9 0.0 1.8e-87 292.4 0.0 1.2 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 EAQ86920.1 - 5.9e-30 103.8 0.0 1.3e-29 102.7 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B_6 PF16661.5 EAQ86920.1 - 2.4e-18 66.3 0.1 3.9e-18 65.6 0.1 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Lactamase_B PF00753.27 EAQ86920.1 - 4.4e-18 66.0 0.8 8.3e-18 65.1 0.8 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily RMMBL PF07521.12 EAQ86920.1 - 9.4e-12 44.7 0.0 1.9e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_3 PF13483.6 EAQ86920.1 - 9.8e-06 25.6 0.4 2.8e-05 24.0 0.1 1.9 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 EAQ86920.1 - 1.7e-05 24.4 0.9 0.0001 21.9 0.7 2.1 2 0 0 2 2 2 1 Beta-lactamase superfamily domain CHB_HEX_C PF03174.13 EAQ86920.1 - 0.11 12.4 0.0 0.96 9.5 0.0 2.5 3 0 0 3 3 3 0 Chitobiase/beta-hexosaminidase C-terminal domain Uds1 PF15456.6 EAQ86921.1 - 2.9e-39 134.2 10.2 2.9e-39 134.2 10.2 9.1 5 2 3 8 8 8 1 Up-regulated During Septation AAA_5 PF07728.14 EAQ86921.1 - 0.0076 16.3 0.6 0.037 14.0 0.6 2.3 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) SHE3 PF17078.5 EAQ86921.1 - 0.0076 16.0 16.9 0.0076 16.0 16.9 5.9 5 1 1 6 6 6 1 SWI5-dependent HO expression protein 3 MOSC PF03473.17 EAQ86921.1 - 0.018 15.0 0.0 0.1 12.6 0.0 2.3 1 0 0 1 1 1 0 MOSC domain Prenyltransf PF01255.19 EAQ86923.1 - 1.5e-76 256.8 0.0 4.1e-76 255.4 0.0 1.7 1 1 0 1 1 1 1 Putative undecaprenyl diphosphate synthase ING PF12998.7 EAQ86923.1 - 3e-07 30.9 0.0 0.00016 22.2 0.0 2.5 2 0 0 2 2 2 2 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 EAQ86923.1 - 0.0023 17.8 1.1 0.0056 16.5 1.1 1.6 1 0 0 1 1 1 1 PHD-finger LRR_6 PF13516.6 EAQ86924.1 - 0.00078 19.3 2.3 0.89 9.8 0.0 4.5 4 0 0 4 4 4 1 Leucine Rich repeat F-box-like PF12937.7 EAQ86924.1 - 0.0037 17.1 0.6 0.012 15.5 0.2 2.2 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 EAQ86924.1 - 0.47 10.9 5.3 1.6 9.2 0.1 4.2 4 1 2 6 6 6 0 Leucine Rich repeats (2 copies) V_ATPase_I PF01496.19 EAQ86925.1 - 0 1027.4 0.0 0 1027.2 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family CheZ PF04344.13 EAQ86925.1 - 0.037 13.9 1.7 0.19 11.6 0.2 2.2 2 0 0 2 2 2 0 Chemotaxis phosphatase, CheZ Baculo_PEP_C PF04513.12 EAQ86925.1 - 0.076 13.1 2.4 3.9 7.5 0.3 2.4 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3584 PF12128.8 EAQ86925.1 - 0.19 9.2 3.5 0.19 9.2 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) DUF1664 PF07889.12 EAQ86925.1 - 0.22 11.6 2.1 7.7 6.6 0.2 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Spc7 PF08317.11 EAQ86925.1 - 0.24 10.3 2.2 3.7 6.4 0.1 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein SesA PF17107.5 EAQ86925.1 - 0.25 11.5 1.6 3 8.0 0.0 2.9 3 0 0 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF3552 PF12072.8 EAQ86925.1 - 0.3 10.5 2.6 6.2 6.2 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) SKA2 PF16740.5 EAQ86925.1 - 0.38 10.5 2.3 14 5.5 0.2 2.6 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 Filament PF00038.21 EAQ86925.1 - 0.4 10.2 9.0 1.2 8.6 0.4 2.6 2 1 0 2 2 2 0 Intermediate filament protein Laminin_II PF06009.12 EAQ86925.1 - 0.47 10.5 3.2 9.2 6.3 0.4 2.3 2 0 0 2 2 2 0 Laminin Domain II DivIC PF04977.15 EAQ86925.1 - 0.49 10.2 4.6 1.2 8.9 0.1 2.9 2 0 0 2 2 2 0 Septum formation initiator CLZ PF16526.5 EAQ86925.1 - 1.1 9.7 5.5 18 5.8 0.3 2.8 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels LXG PF04740.12 EAQ86925.1 - 1.3 8.7 3.7 8.2 6.1 0.2 2.2 2 0 0 2 2 2 0 LXG domain of WXG superfamily Snapin_Pallidin PF14712.6 EAQ86925.1 - 2.4 8.6 5.0 6.3 7.3 0.5 2.8 2 1 0 2 2 2 0 Snapin/Pallidin DHR10 PF18595.1 EAQ86925.1 - 4.1 7.5 8.0 9.1 6.4 2.5 2.7 2 1 0 2 2 2 0 Designed helical repeat protein 10 domain Tcp11 PF05794.13 EAQ86926.1 - 7.9e-104 348.2 0.0 1e-103 347.8 0.0 1.1 1 0 0 1 1 1 1 T-complex protein 11 DDE_3 PF13358.6 EAQ86930.1 - 5.6e-11 42.4 0.5 1.1e-10 41.4 0.4 1.5 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 EAQ86930.1 - 3.7e-06 27.1 0.0 7.4e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 EAQ86930.1 - 0.0074 16.1 0.0 0.016 15.0 0.0 1.6 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 EAQ86930.1 - 0.012 16.2 4.0 0.32 11.6 2.5 3.3 2 1 1 3 3 3 0 Homeodomain-like domain TFIID-18kDa PF02269.16 EAQ86931.1 - 8.1e-20 70.6 0.0 1.4e-19 69.9 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit CENP-T_C PF15511.6 EAQ86931.1 - 9e-05 22.6 0.1 0.00015 21.8 0.1 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Bromo_TP PF07524.13 EAQ86931.1 - 0.00032 20.7 0.0 0.00061 19.7 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated CENP-S PF15630.6 EAQ86931.1 - 0.00036 20.9 0.0 0.00076 19.8 0.0 1.5 1 0 0 1 1 1 1 CENP-S protein Histone PF00125.24 EAQ86931.1 - 0.0026 18.1 0.9 0.026 14.9 0.0 2.1 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EAQ86931.1 - 0.0044 17.3 0.0 0.0044 17.3 0.0 2.3 3 0 0 3 3 3 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 EAQ86931.1 - 0.097 13.2 0.1 0.24 11.9 0.0 1.7 2 0 0 2 2 2 0 Transcription initiation factor TFIID subunit A TFIID-31kDa PF02291.15 EAQ86931.1 - 0.12 12.4 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Macro PF01661.21 EAQ86932.1 - 1.7e-16 60.3 0.0 2.8e-16 59.6 0.0 1.4 1 0 0 1 1 1 1 Macro domain EamA PF00892.20 EAQ86933.1 - 1.1e-17 64.5 32.0 4.2e-11 43.2 8.2 2.1 2 0 0 2 2 2 2 EamA-like transporter family DUF3530 PF12048.8 EAQ86933.1 - 0.17 11.3 0.0 0.26 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) TIP49 PF06068.13 EAQ86934.1 - 2.2e-110 369.2 0.6 1.5e-108 363.2 0.2 2.2 1 1 1 2 2 2 1 TIP49 P-loop domain TIP49_C PF17856.1 EAQ86934.1 - 2e-25 88.7 0.1 4.5e-25 87.6 0.1 1.7 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 EAQ86934.1 - 9.9e-11 42.2 0.1 2.4e-07 31.3 0.1 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EAQ86934.1 - 0.00012 21.9 0.0 0.0003 20.6 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 EAQ86934.1 - 0.0022 18.2 0.2 0.0069 16.6 0.1 1.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EAQ86934.1 - 0.0027 18.1 0.0 0.005 17.2 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 EAQ86934.1 - 0.013 16.1 0.0 0.028 15.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAQ86934.1 - 0.014 15.0 0.1 0.14 11.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain DnaB_C PF03796.15 EAQ86934.1 - 0.019 14.3 0.0 0.039 13.3 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain Zeta_toxin PF06414.12 EAQ86934.1 - 0.02 14.2 0.1 0.046 13.0 0.1 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_19 PF13245.6 EAQ86934.1 - 0.022 15.1 0.2 0.051 13.9 0.2 1.6 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EAQ86934.1 - 0.026 14.2 0.2 0.062 13.0 0.2 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_5 PF07728.14 EAQ86934.1 - 0.042 13.9 0.1 0.093 12.7 0.1 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF2075 PF09848.9 EAQ86934.1 - 0.05 12.8 0.0 0.079 12.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ATPase PF06745.13 EAQ86934.1 - 0.053 12.9 1.0 0.5 9.7 0.1 2.2 2 0 0 2 2 2 0 KaiC Mg_chelatase PF01078.21 EAQ86934.1 - 0.14 11.5 0.1 0.54 9.6 0.1 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI TsaE PF02367.17 EAQ86934.1 - 0.15 12.0 0.1 0.33 11.0 0.1 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 EAQ86934.1 - 0.19 11.6 0.1 0.47 10.4 0.1 1.6 1 0 0 1 1 1 0 NACHT domain HMG_box PF00505.19 EAQ86935.1 - 1.7e-22 79.6 0.7 3.3e-22 78.7 0.7 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EAQ86935.1 - 1.1e-07 32.3 0.6 2.1e-07 31.4 0.6 1.5 1 0 0 1 1 1 1 HMG-box domain MATalpha_HMGbox PF04769.12 EAQ86935.1 - 0.0036 16.6 0.0 0.0056 16.0 0.0 1.2 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 HMG-box DUF3198 PF11433.8 EAQ86935.1 - 0.14 12.0 0.0 20 5.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3198) Dynactin PF12455.8 EAQ86936.1 - 1e-108 362.9 10.8 1e-108 362.9 10.8 3.4 4 0 0 4 4 4 1 Dynein associated protein CAP_GLY PF01302.25 EAQ86936.1 - 8.5e-23 80.2 0.2 1.4e-22 79.4 0.2 1.4 1 0 0 1 1 1 1 CAP-Gly domain DUF2353 PF09789.9 EAQ86936.1 - 3.2e-07 30.0 23.2 3.2e-07 30.0 23.2 4.6 2 2 1 4 4 4 1 Uncharacterized coiled-coil protein (DUF2353) SRP19 PF01922.17 EAQ86937.1 - 4.1e-32 111.0 0.0 9.2e-32 109.9 0.0 1.6 1 0 0 1 1 1 1 SRP19 protein DUF2722 PF10846.8 EAQ86937.1 - 0.0015 17.5 4.0 0.0015 17.5 4.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) YL1 PF05764.13 EAQ86937.1 - 0.0066 16.6 1.2 0.0089 16.2 1.2 1.2 1 0 0 1 1 1 1 YL1 nuclear protein DUF3729 PF12526.8 EAQ86937.1 - 0.19 13.3 0.3 0.19 13.3 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3729) Pex14_N PF04695.13 EAQ86937.1 - 0.2 12.3 9.7 0.28 11.9 6.7 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CCDC53 PF10152.9 EAQ86937.1 - 0.59 10.5 5.9 1.3 9.4 5.9 1.5 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex GET2 PF08690.10 EAQ86937.1 - 5.1 6.7 11.1 12 5.4 7.0 2.2 2 0 0 2 2 2 0 GET complex subunit GET2 Torus PF16131.5 EAQ86938.1 - 0.11 13.2 0.6 0.11 13.2 0.6 2.5 1 1 1 2 2 2 0 Torus domain Apt1 PF10351.9 EAQ86938.1 - 0.17 10.7 0.3 0.25 10.2 0.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain CDP-OH_P_transf PF01066.21 EAQ86940.1 - 1.2e-09 38.7 0.1 1.2e-09 38.7 0.1 2.1 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DDE_3 PF13358.6 EAQ86941.1 - 1.4e-13 50.8 0.0 2.5e-13 50.0 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 EAQ86941.1 - 1e-07 32.1 0.0 2.4e-07 30.9 0.0 1.7 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 EAQ86941.1 - 0.0032 18.0 4.9 0.048 14.3 0.0 3.7 2 2 2 4 4 4 1 Homeodomain-like domain HTH_23 PF13384.6 EAQ86941.1 - 0.008 16.0 0.0 0.022 14.5 0.0 1.8 1 0 0 1 1 1 1 Homeodomain-like domain TAL_effector PF03377.13 EAQ86941.1 - 0.065 13.6 0.1 0.45 10.9 0.0 2.3 2 0 0 2 2 2 0 TAL effector repeat OMPdecase PF00215.24 EAQ86943.1 - 6e-92 307.3 0.3 8.2e-92 306.9 0.3 1.2 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Sporozoite_P67 PF05642.11 EAQ86943.1 - 0.00015 20.0 3.2 0.00019 19.7 3.2 1.1 1 0 0 1 1 1 1 Sporozoite P67 surface antigen Med15 PF09606.10 EAQ86943.1 - 0.0079 15.0 11.0 0.0097 14.7 11.0 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal DDHD PF02862.17 EAQ86943.1 - 0.015 15.5 1.7 0.019 15.1 1.7 1.3 1 0 0 1 1 1 0 DDHD domain DUF2722 PF10846.8 EAQ86943.1 - 0.034 13.1 14.0 0.048 12.6 14.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) eIF-3_zeta PF05091.12 EAQ86943.1 - 0.036 13.0 8.9 0.052 12.5 8.9 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) CDC45 PF02724.14 EAQ86943.1 - 0.038 12.3 4.2 0.04 12.2 4.2 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4407 PF14362.6 EAQ86943.1 - 0.046 13.1 10.3 0.013 14.8 7.3 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Spt20 PF12090.8 EAQ86943.1 - 0.11 12.1 20.9 0.19 11.3 20.9 1.3 1 0 0 1 1 1 0 Spt20 family V_ATPase_I PF01496.19 EAQ86943.1 - 0.18 9.7 2.0 0.2 9.6 2.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Presenilin PF01080.17 EAQ86943.1 - 0.58 8.9 7.8 0.77 8.5 7.8 1.1 1 0 0 1 1 1 0 Presenilin Nuc_deoxyri_tr2 PF15891.5 EAQ86943.1 - 0.77 10.1 5.6 2.3 8.5 5.6 1.8 1 0 0 1 1 1 0 Nucleoside 2-deoxyribosyltransferase like DUF3682 PF12446.8 EAQ86943.1 - 0.83 10.1 14.6 1.8 9.0 14.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) Roughex PF06020.11 EAQ86943.1 - 1.8 7.6 9.8 2.8 6.9 9.8 1.3 1 0 0 1 1 1 0 Drosophila roughex protein ALMT PF11744.8 EAQ86943.1 - 2 7.2 6.1 2.7 6.7 6.1 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF4834 PF16118.5 EAQ86943.1 - 3.6 8.6 9.4 8.1 7.5 9.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) FAM60A PF15396.6 EAQ86943.1 - 4.9 7.1 7.3 7.8 6.4 7.3 1.2 1 0 0 1 1 1 0 Protein Family FAM60A HemX PF04375.14 EAQ86943.1 - 5.3 6.2 16.9 22 4.2 0.1 2.2 2 0 0 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase Paf1 PF03985.13 EAQ86943.1 - 7.4 5.5 14.9 11 4.9 14.9 1.1 1 0 0 1 1 1 0 Paf1 Hid1 PF12722.7 EAQ86943.1 - 9 4.3 7.8 12 3.9 7.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Fungal_trans PF04082.18 EAQ86944.1 - 9.9e-09 34.6 0.0 5.5e-06 25.6 0.0 2.5 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 EAQ86944.1 - 3.4e-07 30.3 12.0 6.3e-07 29.4 12.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PNP_UDP_1 PF01048.20 EAQ86945.1 - 2.2e-07 30.4 0.0 7.7e-07 28.6 0.0 1.9 1 1 0 1 1 1 1 Phosphorylase superfamily NACHT PF05729.12 EAQ86945.1 - 2.6e-05 24.2 0.0 5.4e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 NACHT domain SOG2 PF10428.9 EAQ86946.1 - 2.2 7.4 12.5 2.1 7.5 12.5 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein WD40 PF00400.32 EAQ86947.1 - 1e-139 450.3 56.2 1.6e-10 41.4 0.1 14.1 13 0 0 13 13 13 13 WD domain, G-beta repeat NACHT_N PF17100.5 EAQ86947.1 - 3.1e-76 256.1 0.1 4.9e-76 255.4 0.1 1.3 1 0 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase ANAPC4_WD40 PF12894.7 EAQ86947.1 - 3.7e-53 177.8 3.2 0.0057 16.9 0.0 12.8 2 1 11 13 13 12 12 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EAQ86947.1 - 6.8e-35 120.6 13.6 0.13 11.2 0.0 12.3 1 1 11 12 12 12 12 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EAQ86947.1 - 3.8e-18 65.4 28.4 0.073 11.7 0.1 12.0 9 3 3 12 12 12 6 Nucleoporin Nup120/160 PD40 PF07676.12 EAQ86947.1 - 5.1e-18 64.5 30.0 4.8 7.3 0.1 13.2 13 0 0 13 13 13 8 WD40-like Beta Propeller Repeat NACHT PF05729.12 EAQ86947.1 - 2.6e-14 53.5 0.4 4.8e-14 52.6 0.4 1.4 1 0 0 1 1 1 1 NACHT domain VID27 PF08553.10 EAQ86947.1 - 5.2e-07 29.0 7.5 1.5 7.8 0.1 5.9 1 1 6 7 7 7 1 VID27 C-terminal WD40-like domain Nucleoporin_N PF08801.11 EAQ86947.1 - 5e-06 25.5 3.2 14 4.3 0.1 7.0 1 1 7 9 9 9 0 Nup133 N terminal like Proteasome_A_N PF10584.9 EAQ86947.1 - 0.00016 21.3 8.1 1.7e+02 2.0 0.0 10.1 11 0 0 11 11 11 0 Proteasome subunit A N-terminal signature Ret2_MD PF18528.1 EAQ86947.1 - 0.00055 20.3 0.0 1.5e+02 2.8 0.0 8.2 6 4 6 12 12 12 0 RNA editing 3' terminal uridylyl transferase 2 middle domain Cytochrom_D1 PF02239.16 EAQ86947.1 - 0.015 13.8 5.4 1.4 7.4 0.2 4.2 1 1 0 3 3 3 0 Cytochrome D1 heme domain AAA_16 PF13191.6 EAQ86947.1 - 0.026 14.9 0.0 0.089 13.2 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain ResIII PF04851.15 EAQ86947.1 - 0.042 13.8 0.0 0.08 12.9 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit WD40_like PF17005.5 EAQ86947.1 - 0.061 12.6 0.0 86 2.3 0.0 4.1 5 0 0 5 5 5 0 WD40-like domain DUF2075 PF09848.9 EAQ86947.1 - 0.064 12.5 0.0 0.28 10.4 0.0 2.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.22 EAQ86947.1 - 0.18 12.2 0.0 0.98 9.8 0.0 2.2 2 0 0 2 2 2 0 RNA helicase TetR_C_12 PF16914.5 EAQ86947.1 - 3.4 7.8 21.1 67 3.7 0.1 7.8 1 1 7 10 10 10 0 Bacterial transcriptional repressor C-terminal CENP-N PF05238.13 EAQ86948.1 - 2.9e-101 339.8 0.0 3.6e-101 339.5 0.0 1.0 1 0 0 1 1 1 1 Kinetochore protein CHL4 like GP67 PF17634.2 EAQ86948.1 - 0.057 13.8 0.2 0.057 13.8 0.2 1.6 2 0 0 2 2 2 0 Gene product 67 TatD_DNase PF01026.21 EAQ86949.1 - 4.6e-07 29.5 0.0 6.7e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 TatD related DNase FUSC PF04632.12 EAQ86949.1 - 1.5 7.2 7.6 1.9 6.9 7.6 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Gastrin PF00918.17 EAQ86949.1 - 3.1 8.8 7.1 21 6.1 0.1 2.2 2 0 0 2 2 2 0 Gastrin/cholecystokinin family K_channel_TID PF07941.11 EAQ86949.1 - 8.9 6.8 13.9 30 5.2 13.8 1.9 1 1 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain Ribonuc_red_lgC PF02867.15 EAQ86950.1 - 1.5e-191 637.5 0.0 2e-191 637.1 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 EAQ86950.1 - 5.7e-24 83.9 0.0 1.3e-23 82.8 0.0 1.7 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 EAQ86950.1 - 7.1e-17 61.8 0.0 1.5e-16 60.8 0.0 1.6 1 0 0 1 1 1 1 ATP cone domain CFEM PF05730.11 EAQ86951.1 - 2.6e-08 33.8 1.6 4.7e-08 33.0 1.6 1.4 1 0 0 1 1 1 1 CFEM domain Glyco_transf_4 PF13439.6 EAQ86952.1 - 5.6e-17 62.3 3.7 9.9e-17 61.5 0.2 2.7 3 0 0 3 3 3 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 EAQ86952.1 - 1.6e-10 41.6 0.9 1.6e-10 41.6 0.9 2.2 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glycos_transf_1 PF00534.20 EAQ86952.1 - 0.00018 21.1 0.0 0.00031 20.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 ALG11_N PF15924.5 EAQ86952.1 - 0.00091 19.3 0.0 0.64 10.0 0.0 2.6 1 1 1 2 2 2 2 ALG11 mannosyltransferase N-terminus Glyco_trans_4_5 PF16994.5 EAQ86952.1 - 0.096 12.3 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Glycosyl-transferase family 4 Pkinase PF00069.25 EAQ86953.1 - 7.3e-51 173.1 0.1 5.1e-35 121.1 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ86953.1 - 1e-20 74.1 0.2 1.3e-18 67.2 0.2 3.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAQ86953.1 - 0.00021 20.7 0.0 0.00075 18.9 0.0 1.9 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 EAQ86953.1 - 0.0047 16.9 0.2 0.015 15.3 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EAQ86953.1 - 0.0086 14.9 0.0 0.021 13.6 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Snapin_Pallidin PF14712.6 EAQ86955.1 - 0.033 14.6 1.4 0.1 13.0 0.3 2.3 2 0 0 2 2 2 0 Snapin/Pallidin AAA_13 PF13166.6 EAQ86955.1 - 0.06 12.0 1.6 0.096 11.3 1.6 1.3 1 0 0 1 1 1 0 AAA domain Macoilin PF09726.9 EAQ86955.1 - 0.2 10.2 8.0 0.043 12.4 3.7 1.8 2 0 0 2 2 2 0 Macoilin family FliD_N PF02465.18 EAQ86955.1 - 0.38 11.5 6.7 0.098 13.4 2.8 2.1 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus ANAPC4 PF12896.7 EAQ86955.1 - 0.38 10.2 2.6 0.29 10.6 0.5 1.7 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 4 CSTF_C PF14304.6 EAQ86955.1 - 0.75 9.4 2.7 3.4 7.3 0.1 2.9 3 0 0 3 3 3 0 Transcription termination and cleavage factor C-terminal Tropomyosin PF00261.20 EAQ86955.1 - 0.78 9.1 12.4 0.2 11.0 7.7 2.0 2 0 0 2 2 2 0 Tropomyosin Fib_alpha PF08702.10 EAQ86955.1 - 0.95 9.6 6.2 2.2 8.4 2.9 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family TPR_MLP1_2 PF07926.12 EAQ86955.1 - 2.1 8.4 11.3 0.23 11.5 6.2 2.0 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Com_YlbF PF06133.11 EAQ86955.1 - 7.8 7.2 6.9 4.9 7.8 3.5 2.2 2 0 0 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA RRM_1 PF00076.22 EAQ86956.1 - 2e-41 139.6 0.6 1.7e-18 66.2 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 EAQ86956.1 - 1.7e-20 73.9 0.0 5.9e-20 72.2 0.0 2.0 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_occluded PF16842.5 EAQ86956.1 - 4.9e-05 23.1 0.0 0.58 10.1 0.0 3.2 3 0 0 3 3 3 2 Occluded RNA-recognition motif RRM_3 PF08777.11 EAQ86956.1 - 0.0066 16.5 0.0 0.16 12.0 0.0 2.7 2 0 0 2 2 2 1 RNA binding motif Nup35_RRM_2 PF14605.6 EAQ86956.1 - 0.015 15.3 0.0 4.3 7.4 0.0 3.1 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif PHM7_cyt PF14703.6 EAQ86956.1 - 0.031 14.5 0.1 0.47 10.7 0.1 2.9 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter RRM_7 PF16367.5 EAQ86956.1 - 0.062 13.4 0.0 4.1 7.6 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif RRM_5 PF13893.6 EAQ86956.1 - 0.17 11.5 0.0 0.31 10.6 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cyt-b5 PF00173.28 EAQ86957.1 - 1.8e-16 60.0 0.1 1.8e-16 60.0 0.1 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.13 EAQ86957.1 - 6.2e-13 49.2 17.2 6.2e-13 49.2 17.2 1.6 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily COX14 PF14880.6 EAQ86957.1 - 0.013 15.4 0.7 0.049 13.5 0.3 2.0 2 0 0 2 2 2 0 Cytochrome oxidase c assembly Anth_synt_I_N PF04715.13 EAQ86957.1 - 0.034 14.4 0.5 0.074 13.3 0.1 1.7 2 0 0 2 2 2 0 Anthranilate synthase component I, N terminal region Het-C PF07217.11 EAQ86958.1 - 1.7e-284 944.6 0.0 2.1e-284 944.3 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C PP2C PF00481.21 EAQ86959.1 - 7.1e-17 61.9 0.0 1.4e-10 41.3 0.0 2.5 3 0 0 3 3 3 2 Protein phosphatase 2C YrzK PF17449.2 EAQ86959.1 - 0.1 12.9 0.1 0.21 11.9 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized YrzK-like BTB PF00651.31 EAQ86960.1 - 0.11 12.7 0.5 8.1 6.7 0.0 2.8 3 0 0 3 3 3 0 BTB/POZ domain FTR1 PF03239.14 EAQ86961.1 - 1.2e-49 169.1 9.2 7.3e-27 94.3 1.4 2.0 2 0 0 2 2 2 2 Iron permease FTR1 family DUF389 PF04087.14 EAQ86961.1 - 0.013 15.6 2.8 0.013 15.6 2.8 2.0 3 0 0 3 3 3 0 Domain of unknown function (DUF389) Ferlin_C PF16165.5 EAQ86961.1 - 0.41 10.6 4.6 0.43 10.5 0.0 2.5 2 1 0 2 2 2 0 Ferlin C-terminus YibE_F PF07907.11 EAQ86961.1 - 2.2 7.7 9.5 0.28 10.6 5.0 1.8 2 0 0 2 2 2 0 YibE/F-like protein Yip1 PF04893.17 EAQ86961.1 - 7.8 6.2 14.6 1.3 8.7 8.5 2.4 1 1 1 2 2 2 0 Yip1 domain Cu-oxidase_3 PF07732.15 EAQ86962.1 - 8.4e-43 145.2 2.1 2.1e-42 143.9 0.5 2.3 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.22 EAQ86962.1 - 7e-39 133.5 0.7 4.6e-33 114.6 0.0 2.6 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 EAQ86962.1 - 1.9e-12 47.1 2.3 1.9e-05 24.4 0.0 3.2 3 1 0 3 3 3 2 Multicopper oxidase Abhydrolase_6 PF12697.7 EAQ86964.1 - 0.00029 21.5 3.2 0.00038 21.1 3.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.14 EAQ86964.1 - 0.0032 17.0 0.1 0.0039 16.7 0.1 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 EAQ86964.1 - 0.0057 16.0 0.1 0.015 14.5 0.0 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 EAQ86964.1 - 0.0062 16.3 0.2 0.0089 15.8 0.2 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_8 PF06259.12 EAQ86964.1 - 0.042 13.5 0.1 0.073 12.7 0.1 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase p450 PF00067.22 EAQ86965.1 - 3.5e-58 197.5 0.0 4.6e-58 197.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 TPR_12 PF13424.6 EAQ86966.1 - 2e-34 117.7 14.1 1.6e-10 41.1 0.1 6.1 2 1 1 5 5 5 4 Tetratricopeptide repeat TPR_10 PF13374.6 EAQ86966.1 - 5.6e-26 89.6 11.7 2e-07 30.7 0.0 7.6 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_4 PF07721.14 EAQ86966.1 - 3.2e-08 33.4 31.4 0.2 12.4 0.1 8.6 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_MalT PF17874.1 EAQ86966.1 - 2.4e-07 30.4 15.9 2.4e-05 23.9 7.8 3.2 1 1 1 3 3 3 2 MalT-like TPR region AAA_16 PF13191.6 EAQ86966.1 - 5.3e-06 26.9 0.2 0.00039 20.9 0.0 3.6 4 0 0 4 4 3 1 AAA ATPase domain TPR_19 PF14559.6 EAQ86966.1 - 1.7e-05 25.2 6.2 1 9.9 0.1 6.2 4 2 2 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.6 EAQ86966.1 - 0.00053 20.6 16.5 15 6.7 0.0 7.7 5 2 2 7 7 7 0 Tetratricopeptide repeat TPR_8 PF13181.6 EAQ86966.1 - 0.00082 19.4 1.8 6.8 7.2 0.2 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat AAA_22 PF13401.6 EAQ86966.1 - 0.0038 17.5 0.0 0.014 15.7 0.0 2.0 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 EAQ86966.1 - 0.0082 16.1 0.0 0.028 14.4 0.0 2.0 1 0 0 1 1 1 1 NACHT domain TPR_16 PF13432.6 EAQ86966.1 - 0.0091 16.6 20.2 20 5.9 0.0 6.4 4 2 2 6 6 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 EAQ86966.1 - 0.031 14.4 15.5 0.43 10.8 0.2 6.3 7 0 0 7 7 7 0 Tetratricopeptide repeat NB-ARC PF00931.22 EAQ86966.1 - 0.048 12.8 0.0 1.2 8.2 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain TPR_1 PF00515.28 EAQ86966.1 - 0.15 11.9 8.9 1.5 8.8 0.3 4.9 6 0 0 6 6 6 0 Tetratricopeptide repeat PRODH PF18327.1 EAQ86966.1 - 0.15 12.3 2.4 0.39 11.0 0.5 2.8 3 0 0 3 3 3 0 Proline utilization A proline dehydrogenase N-terminal domain TPR_7 PF13176.6 EAQ86966.1 - 1.2 9.3 12.0 73 3.7 0.1 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 EAQ86966.1 - 1.5 9.6 5.7 67 4.4 0.1 4.6 5 0 0 5 5 4 0 Tetratricopeptide repeat bZIP_2 PF07716.15 EAQ86967.1 - 2.5e-12 46.7 8.6 4.2e-12 45.9 8.6 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 EAQ86967.1 - 0.00054 20.0 7.4 0.00099 19.2 7.4 1.4 1 0 0 1 1 1 1 bZIP transcription factor XhlA PF10779.9 EAQ86967.1 - 0.054 13.7 2.2 0.11 12.7 2.2 1.5 1 0 0 1 1 1 0 Haemolysin XhlA TSC22 PF01166.18 EAQ86967.1 - 0.067 13.5 0.1 0.14 12.5 0.1 1.5 1 0 0 1 1 1 0 TSC-22/dip/bun family betaPIX_CC PF16523.5 EAQ86967.1 - 0.071 12.9 1.4 0.12 12.3 1.4 1.4 1 0 0 1 1 1 0 betaPIX coiled coil TFIIA PF03153.13 EAQ86968.1 - 3.7 7.4 11.3 4.2 7.3 11.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Aminotran_1_2 PF00155.21 EAQ86969.1 - 2.2e-35 122.5 0.0 2.7e-35 122.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II VWA PF00092.28 EAQ86970.1 - 5.7e-09 36.5 0.0 9.3e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 EAQ86970.1 - 0.15 12.7 0.0 0.45 11.2 0.0 1.9 1 1 0 1 1 1 0 von Willebrand factor type A domain SOG2 PF10428.9 EAQ86970.1 - 0.32 10.1 3.3 0.38 9.9 3.3 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Rib_recp_KP_reg PF05104.12 EAQ86970.1 - 0.97 10.5 6.3 1.7 9.7 6.3 1.3 1 0 0 1 1 1 0 Ribosome receptor lysine/proline rich region LRR_4 PF12799.7 EAQ86971.1 - 1.4e-23 82.6 46.7 1.2e-05 25.5 4.1 7.8 4 1 6 10 10 10 10 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EAQ86971.1 - 3.3e-18 65.2 48.5 1.5e-06 27.9 5.1 6.7 3 1 2 6 6 6 4 Leucine rich repeat LRR_9 PF14580.6 EAQ86971.1 - 1.8e-10 40.6 18.7 8.1e-05 22.2 3.5 3.7 2 1 0 3 3 3 3 Leucine-rich repeat LRR_1 PF00560.33 EAQ86971.1 - 0.45 11.3 30.0 13 6.8 0.4 10.0 9 3 1 10 10 10 0 Leucine Rich Repeat IPK PF03770.16 EAQ86974.1 - 6.2e-58 195.9 0.0 1.3e-57 194.9 0.0 1.5 1 0 0 1 1 1 1 Inositol polyphosphate kinase Pam17 PF08566.10 EAQ86974.1 - 0.077 12.8 0.1 0.16 11.8 0.1 1.4 1 0 0 1 1 1 0 Mitochondrial import protein Pam17 Zip PF02535.22 EAQ86974.1 - 2.8 7.1 5.2 5.7 6.1 5.2 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter ATG27 PF09451.10 EAQ86976.1 - 1.2e-45 156.4 0.5 1.9e-45 155.8 0.5 1.2 1 0 0 1 1 1 1 Autophagy-related protein 27 Spt20 PF12090.8 EAQ86977.1 - 3e-59 200.5 0.2 3e-59 200.5 0.2 8.6 4 2 3 7 7 7 1 Spt20 family NTP_transf_3 PF12804.7 EAQ86979.1 - 3.3e-05 24.3 0.0 5.9e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain Fucokinase PF07959.12 EAQ86979.1 - 5.6e-05 22.3 2.3 0.00015 20.9 2.3 1.6 1 1 0 1 1 1 1 L-fucokinase Hexapep PF00132.24 EAQ86979.1 - 8.4e-05 22.1 6.0 0.0063 16.2 1.0 3.5 2 1 2 4 4 4 3 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.23 EAQ86979.1 - 0.00062 19.4 0.0 0.0012 18.4 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyl transferase DUF4954 PF16314.5 EAQ86979.1 - 0.002 16.3 1.0 0.005 15.0 1.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4954) Hexapep_2 PF14602.6 EAQ86979.1 - 0.36 10.6 7.2 1.6 8.5 2.5 3.2 1 1 1 2 2 2 0 Hexapeptide repeat of succinyl-transferase zf-C2H2 PF00096.26 EAQ86981.1 - 0.0021 18.4 5.6 0.0057 17.1 0.6 2.8 1 1 1 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EAQ86981.1 - 0.51 11.3 2.6 0.83 10.7 0.3 2.6 1 1 1 2 2 2 0 C2H2-type zinc finger LRR_6 PF13516.6 EAQ86983.1 - 0.049 13.7 2.3 8.1 6.8 0.0 3.5 3 0 0 3 3 3 0 Leucine Rich repeat LRR_4 PF12799.7 EAQ86983.1 - 0.96 10.0 4.2 15 6.2 0.0 4.3 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) Mito_carr PF00153.27 EAQ86984.1 - 2.6e-29 101.0 0.2 7.1e-15 54.7 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein RNA_pol_Rpc82 PF05645.13 EAQ86985.1 - 1e-74 251.6 0.3 2e-74 250.6 0.1 1.6 2 0 0 2 2 2 1 RNA polymerase III subunit RPC82 HTH_9 PF08221.11 EAQ86985.1 - 6.6e-07 29.3 0.1 0.00058 19.9 0.0 3.3 3 0 0 3 3 3 2 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.17 EAQ86985.1 - 0.013 15.3 0.7 7.3 6.5 0.0 4.3 4 0 0 4 4 4 0 TFIIE alpha subunit ATP-synt_Eps PF04627.13 EAQ86986.1 - 6.1e-21 74.2 1.5 1.6e-20 72.8 1.5 1.8 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain Peptidase_M16 PF00675.20 EAQ86986.1 - 3.1e-13 50.0 0.2 1.6e-12 47.6 0.2 2.0 1 1 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EAQ86986.1 - 5.3e-12 46.1 0.0 2e-11 44.2 0.0 2.0 2 0 0 2 2 2 1 Peptidase M16 inactive domain M16C_assoc PF08367.11 EAQ86986.1 - 0.14 11.3 0.0 0.41 9.7 0.0 1.7 2 0 0 2 2 2 0 Peptidase M16C associated Mak10 PF04112.13 EAQ86987.1 - 4.2e-27 94.7 0.1 1.7e-23 83.0 0.0 2.4 1 1 1 2 2 2 2 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Mito_carr PF00153.27 EAQ86988.1 - 2e-39 133.4 3.4 3e-16 59.1 0.0 3.4 2 1 1 3 3 3 3 Mitochondrial carrier protein Abp2 PF09441.10 EAQ86989.1 - 5.5e-83 277.2 0.0 9.1e-83 276.5 0.0 1.4 1 0 0 1 1 1 1 ARS binding protein 2 DUF3328 PF11807.8 EAQ86989.1 - 0.08 12.7 0.5 0.27 11.0 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3328) Actin PF00022.19 EAQ86991.1 - 8.7e-14 50.9 0.0 8.7e-08 31.2 0.0 2.9 3 1 0 3 3 3 2 Actin GEN1_C PF18380.1 EAQ86992.1 - 9.9e-30 103.5 0.3 2.9e-29 102.0 0.0 2.0 2 0 0 2 2 2 1 Holliday junction resolvase Gen1 C-terminal domain XPG_I PF00867.18 EAQ86992.1 - 4.3e-25 87.9 0.0 8.3e-25 87.0 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 EAQ86992.1 - 0.0008 19.8 0.0 0.0018 18.7 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain SWIB PF02201.18 EAQ86993.1 - 3.5e-18 65.2 0.2 6.2e-18 64.5 0.2 1.4 1 0 0 1 1 1 1 SWIB/MDM2 domain Pkinase PF00069.25 EAQ86994.1 - 3.1e-47 161.2 0.7 2.8e-42 144.9 0.2 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ86994.1 - 2.6e-24 85.9 0.1 5e-24 85.0 0.1 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAQ86994.1 - 0.00013 21.4 0.5 0.053 12.8 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 EAQ86994.1 - 0.00052 19.4 0.0 0.00095 18.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EAQ86994.1 - 0.0046 16.9 0.1 0.012 15.5 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EAQ86994.1 - 0.012 14.6 0.0 0.019 13.9 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain FTA2 PF13095.6 EAQ86994.1 - 0.039 13.6 0.2 4.6 6.8 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 EAQ86994.1 - 0.074 12.6 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 RIO1 family tRNA-synt_1 PF00133.22 EAQ86998.1 - 7.3e-227 754.4 0.0 1e-226 753.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EAQ86998.1 - 2e-26 92.8 0.0 8.1e-26 90.8 0.0 2.0 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 EAQ86998.1 - 3.1e-16 59.1 0.2 1.8e-06 26.9 0.0 4.1 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 EAQ86998.1 - 0.053 12.8 0.0 0.17 11.2 0.0 1.8 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain Sfi1 PF08457.10 EAQ86999.1 - 9.5e-167 556.0 87.9 1.2e-163 545.7 82.0 2.1 1 1 1 2 2 2 2 Sfi1 spindle body protein Ribosomal_L26 PF16906.5 EAQ87000.1 - 1.5e-39 134.3 2.2 1.9e-39 134.0 2.2 1.1 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 EAQ87000.1 - 2.5e-06 27.2 0.4 9.2e-06 25.4 0.6 1.9 2 0 0 2 2 2 1 KOW motif Mo25 PF08569.11 EAQ87001.1 - 1.2e-129 432.4 0.0 1.3e-129 432.2 0.0 1.0 1 0 0 1 1 1 1 Mo25-like L27 PF02828.16 EAQ87001.1 - 0.079 12.7 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 L27 domain F-box-like PF12937.7 EAQ87003.1 - 4e-06 26.6 2.8 1.9e-05 24.5 0.4 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EAQ87003.1 - 0.076 12.9 1.3 0.77 9.7 0.5 3.0 2 1 0 2 2 2 0 F-box domain Ala_racemase_N PF01168.20 EAQ87004.1 - 8.5e-11 41.9 0.0 1.4e-10 41.2 0.0 1.3 1 1 0 1 1 1 1 Alanine racemase, N-terminal domain Apolipoprotein PF01442.18 EAQ87005.1 - 0.00068 19.6 8.4 0.00068 19.6 8.4 10.5 5 2 3 10 10 10 1 Apolipoprotein A1/A4/E domain Cas6_N PF17952.1 EAQ87005.1 - 0.0081 16.4 3.1 3.5 7.9 0.1 3.6 1 1 2 3 3 3 2 Cas6 N-terminal domain MtrB PF05440.12 EAQ87005.1 - 8.3 6.9 5.7 8.3 6.9 0.1 4.0 4 0 0 4 4 4 0 Tetrahydromethanopterin S-methyltransferase subunit B tRNA-synt_2b PF00587.25 EAQ87006.1 - 1.2e-19 70.9 0.0 1.9e-19 70.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 EAQ87006.1 - 1.2e-12 48.0 1.9 8.1e-12 45.3 1.9 2.2 1 1 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Auxin_repressed PF05564.12 EAQ87006.1 - 0.1 13.3 0.0 0.27 11.9 0.0 1.7 1 0 0 1 1 1 0 Dormancy/auxin associated protein bZIP_Maf PF03131.17 EAQ87006.1 - 0.12 12.9 3.1 0.11 13.0 0.5 2.1 2 0 0 2 2 2 0 bZIP Maf transcription factor MS_channel PF00924.18 EAQ87007.1 - 4.1e-16 59.2 1.7 8e-16 58.2 1.7 1.5 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_7 PF13499.6 EAQ87007.1 - 0.0029 18.0 0.0 0.0064 16.9 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 EAQ87007.1 - 0.0042 16.5 0.1 0.0088 15.5 0.1 1.5 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.32 EAQ87007.1 - 0.019 14.5 0.1 0.042 13.4 0.1 1.6 1 0 0 1 1 1 0 EF hand Vma12 PF11712.8 EAQ87007.1 - 5.2 7.1 6.0 1.3 9.1 0.8 2.3 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DLH PF01738.18 EAQ87008.1 - 7.3e-19 68.2 0.0 2.7e-18 66.3 0.0 1.8 1 1 1 2 2 2 1 Dienelactone hydrolase family BAAT_C PF08840.11 EAQ87008.1 - 0.00037 20.5 0.0 0.0033 17.4 0.0 1.9 1 1 1 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal AXE1 PF05448.12 EAQ87008.1 - 0.06 12.0 0.0 0.1 11.3 0.0 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) HSP70 PF00012.20 EAQ87009.1 - 1.8e-257 855.4 3.2 2.1e-257 855.2 3.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EAQ87009.1 - 2.1e-17 63.0 0.0 3.7e-16 58.9 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 EAQ87009.1 - 0.0012 18.6 0.0 0.0026 17.5 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 EAQ87009.1 - 0.0044 17.4 0.8 8.3 6.9 0.0 3.5 3 2 0 3 3 3 2 Cell division protein FtsA Hydantoinase_A PF01968.18 EAQ87009.1 - 0.033 13.5 0.1 0.062 12.6 0.1 1.5 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase StbA PF06406.11 EAQ87009.1 - 0.046 12.9 0.0 0.087 12.0 0.0 1.4 1 0 0 1 1 1 0 StbA protein BcrAD_BadFG PF01869.20 EAQ87009.1 - 0.071 12.6 0.0 3 7.3 0.0 2.4 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family NOP19 PF10863.8 EAQ87009.1 - 0.34 10.7 2.1 6.7 6.5 0.1 2.4 2 0 0 2 2 2 0 Nucleolar protein 19 DUF3128 PF11326.8 EAQ87010.1 - 4.4e-26 91.1 1.7 8e-26 90.2 1.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) Ndc1_Nup PF09531.10 EAQ87010.1 - 0.37 9.4 7.2 0.38 9.4 7.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup GET2 PF08690.10 EAQ87010.1 - 6.6 6.3 10.2 12 5.4 10.2 1.5 1 0 0 1 1 1 0 GET complex subunit GET2 RNA12 PF10443.9 EAQ87011.1 - 5.8e-169 562.5 1.1 5.8e-169 562.5 1.1 1.7 2 0 0 2 2 2 1 RNA12 protein RRM_1 PF00076.22 EAQ87011.1 - 4.4e-05 23.2 0.3 0.00026 20.8 0.0 2.4 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2487 PF10673.9 EAQ87011.1 - 0.0011 19.1 0.0 0.0026 17.8 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2487) ATPase_2 PF01637.18 EAQ87011.1 - 0.086 12.7 1.8 0.84 9.5 0.2 3.0 3 1 0 3 3 3 0 ATPase domain predominantly from Archaea Mif2_N PF15624.6 EAQ87012.1 - 1.2e-39 136.1 1.4 1.2e-39 136.1 1.4 3.9 3 1 0 3 3 3 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal CENP-C_C PF11699.8 EAQ87012.1 - 1.4e-34 118.1 0.6 2.3e-34 117.4 0.6 1.3 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_2 PF07883.11 EAQ87012.1 - 0.00031 20.4 0.0 0.00085 19.0 0.0 1.8 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 EAQ87012.1 - 0.17 11.5 0.1 0.34 10.5 0.1 1.4 1 0 0 1 1 1 0 Cupin RNase_HII PF01351.18 EAQ87013.1 - 9.3e-46 156.2 0.0 1.4e-45 155.6 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease HII RHD3 PF05879.12 EAQ87014.1 - 1.2e-298 992.4 0.0 1.5e-298 992.1 0.0 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.19 EAQ87014.1 - 2.5e-07 30.3 0.1 4.3e-07 29.5 0.1 1.3 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain AAA_28 PF13521.6 EAQ87014.1 - 1.6e-05 25.2 0.0 4.5e-05 23.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain Dynamin_N PF00350.23 EAQ87014.1 - 2.3e-05 24.5 0.0 5.5e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 EAQ87014.1 - 0.00019 21.5 0.0 0.00045 20.3 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Cys_Met_Meta_PP PF01053.20 EAQ87014.1 - 0.11 11.0 0.0 0.17 10.3 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Septin PF00735.18 EAQ87014.1 - 0.11 11.7 0.1 0.19 10.9 0.1 1.4 1 0 0 1 1 1 0 Septin Fructosamin_kin PF03881.14 EAQ87015.1 - 4.8e-14 52.2 0.0 5.7e-14 52.0 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase Med18 PF09637.10 EAQ87016.1 - 2.7e-07 30.7 0.0 0.00014 21.8 0.0 2.2 1 1 1 2 2 2 2 Med18 protein Fungal_trans_2 PF11951.8 EAQ87016.1 - 8.6e-05 21.5 0.2 0.00016 20.7 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EAQ87016.1 - 0.0064 16.6 4.3 0.016 15.3 4.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amidohydro_1 PF01979.20 EAQ87017.1 - 1.3e-59 202.3 0.1 1.5e-59 202.1 0.1 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EAQ87017.1 - 1.9e-15 57.3 0.1 1.6e-11 44.3 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family A_deaminase PF00962.22 EAQ87017.1 - 0.00044 19.7 0.0 0.0012 18.3 0.0 1.6 2 0 0 2 2 2 1 Adenosine/AMP deaminase HET PF06985.11 EAQ87018.1 - 5.9e-23 81.8 0.1 1e-22 81.1 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) TPR_12 PF13424.6 EAQ87020.1 - 1.1e-09 38.4 0.0 0.0028 17.9 0.0 2.9 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 EAQ87020.1 - 0.0004 21.0 0.0 6.9 7.8 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat Clr5 PF14420.6 EAQ87020.1 - 0.00042 20.5 0.2 1.3 9.3 0.0 2.9 2 0 0 2 2 2 2 Clr5 domain TPR_10 PF13374.6 EAQ87020.1 - 0.0045 16.8 0.0 0.88 9.5 0.1 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_4 PF07721.14 EAQ87020.1 - 0.025 15.2 0.9 0.58 10.9 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 EAQ87020.1 - 0.052 13.7 0.1 1.7 8.9 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 EAQ87020.1 - 0.12 12.7 0.1 1.7 9.0 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 EAQ87020.1 - 0.16 12.1 0.1 8.9 6.6 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Glyco_hydro_61 PF03443.14 EAQ87021.1 - 1.1e-57 195.3 1.0 1.4e-57 195.0 1.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Glyco_hydro_61 PF03443.14 EAQ87022.1 - 2.5e-57 194.1 0.2 3.2e-57 193.8 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 GMC_oxred_N PF00732.19 EAQ87023.1 - 4.7e-30 105.0 0.0 7.5e-30 104.3 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 EAQ87023.1 - 3.4e-10 39.6 0.2 0.00017 20.8 0.1 2.3 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 EAQ87023.1 - 3.3e-06 26.9 1.9 6.3e-05 22.7 1.9 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EAQ87023.1 - 3e-05 24.2 0.0 3e-05 24.2 0.0 1.9 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EAQ87023.1 - 9.6e-05 21.8 0.0 0.00037 19.8 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EAQ87023.1 - 0.0032 16.2 0.0 0.01 14.6 0.0 1.7 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 EAQ87023.1 - 0.015 14.7 0.1 0.49 9.7 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EAQ87023.1 - 0.018 14.3 0.3 0.22 10.8 0.3 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EAQ87023.1 - 0.019 14.1 0.1 0.028 13.5 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.17 EAQ87023.1 - 0.032 13.5 0.1 0.058 12.6 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.27 EAQ87023.1 - 0.044 14.3 0.0 1.6 9.3 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EAQ87023.1 - 0.093 12.0 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Prenyltrans PF00432.21 EAQ87024.1 - 0.011 15.5 0.2 0.021 14.6 0.2 1.4 1 0 0 1 1 1 0 Prenyltransferase and squalene oxidase repeat Pho88 PF10032.9 EAQ87025.1 - 7.9e-79 263.1 0.0 8.9e-79 263.0 0.0 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) DUF1240 PF06836.12 EAQ87025.1 - 0.097 13.2 0.1 0.16 12.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1240) XPA_C PF05181.12 EAQ87026.1 - 2.1e-25 88.4 3.1 2.1e-25 88.4 3.1 2.4 2 0 0 2 2 2 1 XPA protein C-terminus XPA_N PF01286.18 EAQ87026.1 - 0.0029 17.6 5.7 0.0072 16.3 5.7 1.7 1 0 0 1 1 1 1 XPA protein N-terminal Striatin PF08232.12 EAQ87027.1 - 3.5e-31 108.9 7.3 3.5e-31 108.9 7.3 2.7 2 1 0 2 2 2 1 Striatin family WD40 PF00400.32 EAQ87027.1 - 1.6e-24 85.7 19.9 0.00021 22.0 0.0 7.5 7 1 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAQ87027.1 - 5e-06 26.7 0.2 0.82 10.0 0.0 4.6 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain ADH_N_2 PF16884.5 EAQ87027.1 - 0.011 15.6 0.0 0.091 12.7 0.0 2.2 2 0 0 2 2 2 0 N-terminal domain of oxidoreductase Cytochrom_D1 PF02239.16 EAQ87027.1 - 0.099 11.1 0.0 0.2 10.1 0.0 1.4 1 0 0 1 1 1 0 Cytochrome D1 heme domain Ge1_WD40 PF16529.5 EAQ87027.1 - 0.14 11.0 0.0 0.5 9.3 0.0 1.9 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Asp PF00026.23 EAQ87028.1 - 4.3e-70 236.6 2.9 6.5e-68 229.5 2.9 2.0 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EAQ87028.1 - 6.5e-14 52.6 2.2 1.5e-09 38.3 2.0 3.2 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EAQ87028.1 - 0.0014 19.2 0.7 1.6 9.4 0.3 3.2 2 1 0 2 2 2 2 Aspartyl protease PTR2 PF00854.21 EAQ87029.1 - 3.7e-43 147.9 0.4 5.4e-43 147.3 0.4 1.2 1 0 0 1 1 1 1 POT family RVT_1 PF00078.27 EAQ87030.1 - 5.8e-48 163.3 0.0 1e-47 162.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 EAQ87030.1 - 2.3e-12 46.8 0.0 7.1e-12 45.2 0.0 1.9 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 EAQ87030.1 - 2.1e-05 24.1 0.2 5.6e-05 22.8 0.2 1.7 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RecC_C PF17946.1 EAQ87030.1 - 0.055 13.2 4.9 1.1 9.0 0.6 2.7 2 0 0 2 2 2 0 RecC C-terminal domain Rubredoxin_2 PF18073.1 EAQ87030.1 - 4.1 7.2 10.2 0.36 10.6 3.8 2.3 2 0 0 2 2 2 0 Rubredoxin metal binding domain Ribosomal_S19 PF00203.21 EAQ87031.1 - 2.5e-23 81.7 0.0 3.7e-23 81.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 TFIID_30kDa PF03540.13 EAQ87032.1 - 1.7e-25 88.7 0.3 2.6e-25 88.1 0.3 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit FoP_duplication PF13865.6 EAQ87032.1 - 0.094 13.3 0.4 0.23 12.1 0.4 1.6 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Bromo_TP PF07524.13 EAQ87032.1 - 0.17 11.9 0.1 20 5.3 0.0 2.3 2 0 0 2 2 2 0 Bromodomain associated Mre11_DNA_bind PF04152.14 EAQ87033.1 - 9.6e-38 130.2 0.6 9.6e-38 130.2 0.6 2.3 2 1 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 EAQ87033.1 - 1.8e-14 54.8 1.1 3e-14 54.0 1.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EAQ87033.1 - 0.001 19.3 0.0 0.0078 16.4 0.0 2.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Ribosomal_60s PF00428.19 EAQ87033.1 - 2.7 8.6 11.7 12 6.6 11.7 2.1 1 0 0 1 1 1 0 60s Acidic ribosomal protein ANAPC10 PF03256.16 EAQ87034.1 - 2.7e-47 160.8 0.0 3.7e-47 160.4 0.0 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.25 EAQ87034.1 - 0.019 15.0 0.0 0.037 14.1 0.0 1.5 1 0 0 1 1 1 0 F5/8 type C domain PITH PF06201.13 EAQ87034.1 - 0.033 14.4 0.0 0.098 12.9 0.0 1.7 1 1 1 2 2 2 0 PITH domain Helitron_like_N PF14214.6 EAQ87035.1 - 4.3e-34 118.4 0.4 8.6e-34 117.4 0.4 1.5 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.14 EAQ87035.1 - 2.1e-31 109.4 0.0 2.5e-27 96.0 0.0 2.3 2 0 0 2 2 2 2 PIF1-like helicase MULE PF10551.9 EAQ87035.1 - 5.8e-19 68.3 0.0 1.5e-18 67.0 0.0 1.8 1 0 0 1 1 1 1 MULE transposase domain DDE_1 PF03184.19 EAQ87035.1 - 5.9e-13 48.8 0.0 1.2e-12 47.8 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease AAA_30 PF13604.6 EAQ87035.1 - 8.4e-12 45.2 0.1 5.5e-11 42.5 0.0 2.4 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.6 EAQ87035.1 - 0.0012 19.2 0.0 0.0025 18.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EAQ87035.1 - 0.083 13.2 0.0 0.26 11.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain Torsin PF06309.11 EAQ87035.1 - 0.14 12.3 0.0 0.29 11.2 0.0 1.4 1 0 0 1 1 1 0 Torsin zf-RVT PF13966.6 EAQ87036.1 - 0.14 12.9 0.0 0.27 12.0 0.0 1.5 2 0 0 2 2 2 0 zinc-binding in reverse transcriptase DDE_1 PF03184.19 EAQ87037.1 - 1.3e-13 51.0 0.0 2.2e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.16 EAQ87037.1 - 3.9e-05 23.3 0.1 9.1e-05 22.1 0.1 1.6 1 0 0 1 1 1 1 helix-turn-helix, Psq domain WD40_alt PF14077.6 EAQ87037.1 - 0.013 15.4 0.0 0.028 14.3 0.0 1.5 1 0 0 1 1 1 0 Alternative WD40 repeat motif DDE_3 PF13358.6 EAQ87037.1 - 0.025 14.3 0.0 0.058 13.2 0.0 1.6 1 0 0 1 1 1 0 DDE superfamily endonuclease zf-RVT PF13966.6 EAQ87038.1 - 0.04 14.6 0.0 1.4 9.6 0.0 2.8 3 0 0 3 3 3 0 zinc-binding in reverse transcriptase FliX PF10768.9 EAQ87039.1 - 0.019 15.5 0.8 0.03 14.8 0.8 1.4 1 1 0 1 1 1 0 Class II flagellar assembly regulator AT_hook PF02178.19 EAQ87039.1 - 0.035 14.0 4.3 0.066 13.1 4.3 1.5 1 0 0 1 1 1 0 AT hook motif FAD-SLDH PF12318.8 EAQ87039.1 - 0.12 12.4 0.1 0.15 12.2 0.1 1.1 1 0 0 1 1 1 0 Membrane bound FAD containing D-sorbitol dehydrogenase Helicase_C PF00271.31 EAQ87041.1 - 1.4e-08 35.0 0.1 3.3e-08 33.8 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EAQ87041.1 - 6.4e-05 23.0 0.0 0.00011 22.2 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAQ87041.1 - 0.0013 18.5 0.0 0.0025 17.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DDE_1 PF03184.19 EAQ87043.1 - 1.4e-13 50.9 0.0 2.5e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.16 EAQ87043.1 - 4.6e-05 23.1 0.1 0.00011 21.9 0.1 1.6 1 0 0 1 1 1 1 helix-turn-helix, Psq domain DDE_3 PF13358.6 EAQ87043.1 - 0.0097 15.7 0.0 0.017 14.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease WD40_alt PF14077.6 EAQ87043.1 - 0.015 15.1 0.0 0.032 14.1 0.0 1.5 1 0 0 1 1 1 0 Alternative WD40 repeat motif THOC7 PF05615.13 EAQ87044.1 - 0.032 14.5 0.9 0.059 13.6 0.9 1.4 1 0 0 1 1 1 0 Tho complex subunit 7 FKBP_N PF01346.18 EAQ87044.1 - 0.083 13.9 0.3 0.27 12.2 0.3 1.8 1 0 0 1 1 1 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Rogdi_lz PF10259.9 EAQ87044.1 - 0.11 11.9 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Rogdi leucine zipper containing protein SAPIS-gp6 PF16722.5 EAQ87044.1 - 0.14 12.6 2.1 0.28 11.6 2.1 1.4 1 0 0 1 1 1 0 Pathogenicity island protein gp6 in Staphylococcus DinB_2 PF12867.7 EAQ87044.1 - 0.16 12.5 0.0 0.49 10.9 0.0 1.8 2 0 0 2 2 2 0 DinB superfamily DUF1043 PF06295.12 EAQ87044.1 - 0.21 11.6 1.1 0.34 10.9 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) EMC3_TMCO1 PF01956.16 EAQ87044.1 - 0.29 10.8 0.5 0.52 10.0 0.5 1.3 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like RVT_1 PF00078.27 EAQ87046.1 - 5.4e-07 29.4 0.0 1.1e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) eIF3m_C_helix PF18005.1 EAQ87046.1 - 9.9 6.0 6.7 41 4.0 0.1 3.6 3 0 0 3 3 3 0 eIF3 subunit M, C-terminal helix Glyco_hydr_30_2 PF14587.6 EAQ87047.1 - 1.5e-16 61.0 0.8 7.8e-16 58.6 0.0 2.1 1 1 1 2 2 2 1 O-Glycosyl hydrolase family 30 Glyco_hydro_59 PF02057.15 EAQ87047.1 - 7.9e-15 54.8 0.5 1.3e-14 54.2 0.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 Glyco_hydro_30C PF17189.4 EAQ87047.1 - 2.2e-12 47.0 4.7 1.3e-11 44.6 5.2 2.1 2 1 0 2 2 2 1 Glycosyl hydrolase family 30 beta sandwich domain Glyco_hydro_30 PF02055.16 EAQ87047.1 - 1.3e-08 34.2 0.8 4.4e-08 32.5 0.8 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Alpha_GJ PF03229.13 EAQ87048.1 - 0.032 14.8 2.6 0.082 13.5 2.6 1.6 1 0 0 1 1 1 0 Alphavirus glycoprotein J AltA1 PF16541.5 EAQ87049.1 - 1.2e-24 87.3 1.0 1.4e-24 87.0 1.0 1.1 1 0 0 1 1 1 1 Alternaria alternata allergen 1 Macin PF14865.6 EAQ87049.1 - 0.024 15.2 0.2 0.068 13.7 0.2 1.7 1 0 0 1 1 1 0 Macin Ge1_WD40 PF16529.5 EAQ87050.1 - 0.0088 15.0 0.0 0.07 12.1 0.0 2.3 2 1 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF4041 PF13250.6 EAQ87050.1 - 0.14 12.1 0.4 4.4 7.3 0.0 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF4041) Spc24 PF08286.11 EAQ87050.1 - 6 7.2 6.8 3.2 8.0 2.6 2.7 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 DDE_1 PF03184.19 EAQ87051.1 - 2.1e-26 92.7 0.0 3.4e-26 92.0 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.16 EAQ87051.1 - 2.3e-09 36.8 0.0 5.9e-09 35.5 0.0 1.7 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.16 EAQ87051.1 - 2.3e-08 33.9 0.0 1.4e-07 31.4 0.0 2.1 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.6 EAQ87051.1 - 8.2e-05 22.4 0.0 0.0098 15.7 0.0 2.5 2 0 0 2 2 2 1 DDE superfamily endonuclease SpoIIID PF12116.8 EAQ87051.1 - 0.035 14.2 0.0 0.1 12.7 0.0 1.7 1 0 0 1 1 1 0 Stage III sporulation protein D ZapB PF06005.12 EAQ87051.1 - 0.15 12.6 1.1 0.62 10.5 1.1 2.2 1 0 0 1 1 1 0 Cell division protein ZapB BC10 PF06726.12 EAQ87052.1 - 2.7e-16 59.5 12.1 4.6e-16 58.8 12.1 1.3 1 0 0 1 1 1 1 Bladder cancer-related protein BC10 Y_phosphatase PF00102.27 EAQ87053.1 - 6.4e-55 186.3 0.0 3e-31 108.8 0.0 4.2 3 1 0 3 3 3 3 Protein-tyrosine phosphatase Rhodanese PF00581.20 EAQ87053.1 - 1.2e-15 57.9 0.0 3.7e-15 56.4 0.0 1.9 2 0 0 2 2 2 1 Rhodanese-like domain Y_phosphatase3 PF13350.6 EAQ87053.1 - 0.089 12.7 0.1 0.17 11.9 0.1 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family DSPc PF00782.20 EAQ87053.1 - 0.27 11.1 0.2 0.6 9.9 0.2 1.5 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain AAA PF00004.29 EAQ87054.1 - 3.4e-44 150.5 0.0 5.5e-44 149.8 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EAQ87054.1 - 1.3e-14 53.7 0.0 2.5e-14 52.8 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 EAQ87054.1 - 4.6e-08 33.1 0.0 1.2e-07 31.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EAQ87054.1 - 6.7e-08 32.8 0.0 1.2e-07 32.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 EAQ87054.1 - 1.3e-06 28.9 0.0 6.5e-05 23.4 0.0 2.7 2 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 EAQ87054.1 - 9.6e-06 25.9 0.2 0.0032 17.8 0.2 2.3 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 EAQ87054.1 - 3e-05 23.8 0.0 5.6e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 EAQ87054.1 - 0.0003 21.3 0.1 0.0092 16.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 EAQ87054.1 - 0.00058 19.2 0.0 0.0011 18.2 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 EAQ87054.1 - 0.00091 19.4 0.0 0.0014 18.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.11 EAQ87054.1 - 0.0016 18.3 0.0 0.0055 16.6 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 EAQ87054.1 - 0.0018 18.1 0.0 0.0028 17.4 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 EAQ87054.1 - 0.0048 16.3 0.0 0.011 15.2 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI ATPase PF06745.13 EAQ87054.1 - 0.005 16.2 0.0 0.011 15.1 0.0 1.5 2 0 0 2 2 2 1 KaiC TsaE PF02367.17 EAQ87054.1 - 0.0064 16.5 0.0 0.01 15.8 0.0 1.3 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 EAQ87054.1 - 0.0068 16.7 0.0 0.011 15.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 EAQ87054.1 - 0.011 15.5 0.1 0.055 13.2 0.0 2.1 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_7 PF12775.7 EAQ87054.1 - 0.016 14.7 0.0 0.025 14.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 EAQ87054.1 - 0.017 14.9 0.1 0.044 13.5 0.1 2.0 2 1 0 2 2 2 0 AAA domain PhoH PF02562.16 EAQ87054.1 - 0.017 14.6 0.0 0.082 12.4 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein AAA_14 PF13173.6 EAQ87054.1 - 0.019 15.0 0.0 0.028 14.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 EAQ87054.1 - 0.02 14.1 0.0 0.032 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RNA_helicase PF00910.22 EAQ87054.1 - 0.02 15.3 0.0 0.036 14.5 0.0 1.4 1 0 0 1 1 1 0 RNA helicase Parvo_NS1 PF01057.17 EAQ87054.1 - 0.039 13.0 0.0 0.064 12.3 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_25 PF13481.6 EAQ87054.1 - 0.045 13.3 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EAQ87054.1 - 0.061 12.6 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_17 PF13207.6 EAQ87054.1 - 0.089 13.2 0.0 0.2 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EAQ87054.1 - 0.14 12.1 0.0 0.41 10.5 0.0 1.7 2 0 0 2 2 2 0 NACHT domain AAA_11 PF13086.6 EAQ87054.1 - 0.14 11.9 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 EAQ87054.1 - 0.14 12.5 0.0 0.33 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Na_Ca_ex PF01699.24 EAQ87055.1 - 2.3e-23 82.8 28.2 8.8e-16 58.2 12.3 3.9 5 0 0 5 5 5 2 Sodium/calcium exchanger protein YccF PF03733.13 EAQ87055.1 - 2.1e-15 57.2 12.3 2.1e-15 57.2 12.3 4.3 4 0 0 4 4 4 2 Inner membrane component domain DUF1996 PF09362.10 EAQ87056.1 - 2.4e-70 237.2 1.0 3.1e-70 236.8 1.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Inositol_P PF00459.25 EAQ87058.1 - 2.1e-33 116.0 0.0 6.7e-33 114.4 0.0 1.8 1 1 0 1 1 1 1 Inositol monophosphatase family R3H PF01424.22 EAQ87059.1 - 1.9e-10 40.6 0.2 3.7e-10 39.6 0.2 1.5 1 0 0 1 1 1 1 R3H domain RRM_1 PF00076.22 EAQ87059.1 - 2.2e-08 33.8 0.0 3.7e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_2 PF04059.12 EAQ87059.1 - 0.069 13.4 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif 2 RPN2_C PF18004.1 EAQ87060.1 - 0.018 15.0 2.1 0.03 14.2 2.1 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Histone PF00125.24 EAQ87061.1 - 2.8e-18 66.5 0.0 3.6e-18 66.2 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 EAQ87061.1 - 9.1e-13 47.7 0.1 2e-12 46.6 0.1 1.6 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 EAQ87061.1 - 2.7e-05 24.3 0.0 4.3e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Peptidase_M64 PF09471.10 EAQ87061.1 - 0.097 12.2 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 IgA Peptidase M64 F-box PF00646.33 EAQ87063.1 - 1.7e-09 37.3 0.4 3.7e-09 36.2 0.4 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EAQ87063.1 - 9.7e-07 28.6 0.8 9.7e-07 28.6 0.8 1.9 2 0 0 2 2 2 1 F-box-like HD PF01966.22 EAQ87064.1 - 0.00057 20.1 0.2 0.00082 19.6 0.2 1.3 1 0 0 1 1 1 1 HD domain Imm48 PF15574.6 EAQ87064.1 - 0.17 11.7 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 Immunity protein 48 MULE PF10551.9 EAQ87065.1 - 5.2e-21 74.9 0.2 1.5e-20 73.4 0.2 1.8 1 0 0 1 1 1 1 MULE transposase domain FAR1 PF03101.15 EAQ87065.1 - 0.0011 19.6 0.5 0.003 18.2 0.5 1.7 1 0 0 1 1 1 1 FAR1 DNA-binding domain Vps4_C PF09336.10 EAQ87065.1 - 0.13 12.2 0.1 11 6.1 0.0 3.2 3 0 0 3 3 3 0 Vps4 C terminal oligomerisation domain RdRP PF05183.12 EAQ87066.1 - 2.1e-141 472.5 0.0 8e-104 348.4 0.0 2.1 2 0 0 2 2 2 2 RNA dependent RNA polymerase Meth_synt_2 PF01717.18 EAQ87067.1 - 4.9e-07 29.3 0.0 1.4e-05 24.5 0.0 2.7 2 1 0 2 2 2 1 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 EAQ87067.1 - 0.0065 16.0 0.0 0.01 15.3 0.0 1.3 1 0 0 1 1 1 1 Cobalamin-independent synthase, N-terminal domain Abhydrolase_6 PF12697.7 EAQ87068.1 - 2.3e-11 44.7 0.3 5.2e-11 43.6 0.3 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EAQ87068.1 - 3.9e-08 33.3 0.0 3.3e-07 30.2 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EAQ87068.1 - 3.4e-05 23.2 0.0 0.00011 21.6 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 EthD PF07110.11 EAQ87068.1 - 0.00011 23.3 0.3 0.1 13.7 0.1 2.8 2 0 0 2 2 2 2 EthD domain Ndr PF03096.14 EAQ87068.1 - 0.00056 18.7 0.0 0.0013 17.5 0.0 1.6 1 1 0 1 1 1 1 Ndr family DUF4286 PF14114.6 EAQ87068.1 - 0.003 18.0 0.0 2.2 8.8 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4286) Esterase PF00756.20 EAQ87068.1 - 0.028 14.0 0.0 0.052 13.2 0.0 1.4 1 0 0 1 1 1 0 Putative esterase LPMO_10 PF03067.15 EAQ87069.1 - 1.3e-09 39.1 0.2 1.9e-09 38.5 0.2 1.2 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading CDH-cyt PF16010.5 EAQ87070.1 - 1e-37 129.6 4.5 1.6e-21 76.8 0.2 2.0 1 1 1 2 2 2 2 Cytochrome domain of cellobiose dehydrogenase DUF2985 PF11204.8 EAQ87071.1 - 7.3e-20 70.9 2.0 1.2e-19 70.2 2.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) DUF1296 PF06972.11 EAQ87071.1 - 0.33 11.1 2.3 0.86 9.8 2.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1296) MetallophosC PF16370.5 EAQ87072.1 - 0.037 14.3 0.0 0.054 13.7 0.0 1.2 1 0 0 1 1 1 0 C terminal of Calcineurin-like phosphoesterase zf-GRF PF06839.12 EAQ87072.1 - 0.056 13.6 0.5 0.1 12.7 0.5 1.4 1 0 0 1 1 1 0 GRF zinc finger Phage_Nu1 PF07471.12 EAQ87072.1 - 0.11 12.3 0.0 0.14 11.9 0.0 1.1 1 0 0 1 1 1 0 Phage DNA packaging protein Nu1 RVT_1 PF00078.27 EAQ87073.1 - 7.2e-48 163.0 0.0 1.1e-47 162.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MFS_1 PF07690.16 EAQ87073.1 - 9.3e-37 126.8 48.9 9.3e-37 126.8 48.9 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EAQ87073.1 - 3e-17 62.3 16.9 4.7e-17 61.6 16.9 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Exo_endo_phos_2 PF14529.6 EAQ87073.1 - 3.8e-12 46.1 0.0 6.7e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 EAQ87073.1 - 3.5e-05 23.5 0.1 7.6e-05 22.3 0.1 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family PolyG_pol PF01518.16 EAQ87073.1 - 0.065 11.9 0.5 0.11 11.2 0.5 1.2 1 0 0 1 1 1 0 Sigma NS protein RecC_C PF17946.1 EAQ87073.1 - 0.083 12.7 4.9 1.1 8.9 0.6 2.4 2 0 0 2 2 2 0 RecC C-terminal domain AA_permease_2 PF13520.6 EAQ87074.1 - 2.4e-70 237.5 15.9 2.6e-70 237.4 15.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EAQ87074.1 - 3.3e-13 49.0 15.2 4.5e-13 48.6 15.2 1.0 1 0 0 1 1 1 1 Amino acid permease DUF5368 PF17336.2 EAQ87074.1 - 0.097 12.8 0.5 0.097 12.8 0.5 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF5368) Aa_trans PF01490.18 EAQ87074.1 - 3.7 6.2 11.9 4 6.0 11.2 1.5 1 1 0 1 1 1 0 Transmembrane amino acid transporter protein RVT_1 PF00078.27 EAQ87075.1 - 1.9e-31 109.3 0.0 8.7e-31 107.2 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Dimer_Tnp_hAT PF05699.14 EAQ87075.1 - 1.4e-14 53.7 0.1 3.3e-14 52.4 0.1 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-CCHC PF00098.23 EAQ87075.1 - 0.0024 17.9 1.7 0.0024 17.9 1.7 2.5 2 0 0 2 2 2 1 Zinc knuckle Herpes_pp85 PF04637.12 EAQ87075.1 - 0.22 9.9 2.4 0.4 9.0 2.4 1.3 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) CASP_C PF08172.12 EAQ87075.1 - 0.32 10.3 3.1 0.88 8.9 3.1 1.7 1 0 0 1 1 1 0 CASP C terminal PI-PLC-X PF00388.19 EAQ87076.1 - 3.8e-49 166.0 0.0 5.7e-49 165.4 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 EAQ87076.1 - 4.1e-35 120.6 0.0 7.5e-35 119.7 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain IMUP PF15761.5 EAQ87076.1 - 0.0071 17.0 1.1 0.019 15.6 1.1 1.7 1 0 0 1 1 1 1 Immortalisation up-regulated protein Glyco_hydro_7 PF00840.20 EAQ87077.1 - 1.1e-183 610.9 12.6 1.2e-183 610.7 12.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 DUF3764 PF12594.8 EAQ87077.1 - 0.035 14.2 0.0 0.11 12.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3764) Dimer_Tnp_hAT PF05699.14 EAQ87078.1 - 1.2e-17 63.5 0.0 3e-17 62.2 0.0 1.8 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Pyr_redox_2 PF07992.14 EAQ87079.1 - 9e-34 117.0 0.0 4e-33 114.9 0.0 1.7 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EAQ87079.1 - 5.9e-10 39.6 1.0 7.4e-09 36.1 0.0 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EAQ87079.1 - 1.1e-05 24.5 1.0 1.2 7.9 0.1 3.2 2 1 1 3 3 3 3 Tryptophan halogenase NAD_binding_9 PF13454.6 EAQ87079.1 - 0.00036 20.6 0.3 11 6.0 0.0 4.5 4 1 1 5 5 5 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 EAQ87079.1 - 0.00056 19.3 0.0 0.0019 17.5 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EAQ87079.1 - 0.0031 16.7 0.1 0.012 14.8 0.0 2.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.12 EAQ87079.1 - 0.0032 16.6 0.3 0.25 10.4 0.0 3.1 3 1 0 4 4 4 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 EAQ87079.1 - 0.026 13.6 0.3 6.7 5.7 0.1 3.0 3 0 0 3 3 3 0 FAD binding domain NAD_binding_8 PF13450.6 EAQ87079.1 - 0.078 13.2 0.2 2.8 8.3 0.0 2.5 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EAQ87079.1 - 0.17 10.6 1.2 1.7 7.2 0.0 2.9 5 0 0 5 5 5 0 HI0933-like protein FAD_oxidored PF12831.7 EAQ87079.1 - 0.19 11.0 1.9 14 4.9 0.3 3.0 2 1 1 3 3 3 0 FAD dependent oxidoreductase UPRTase PF14681.6 EAQ87080.1 - 1.2e-37 129.4 0.1 3e-37 128.1 0.1 1.7 2 0 0 2 2 2 1 Uracil phosphoribosyltransferase HAD PF12710.7 EAQ87080.1 - 3.2e-24 86.4 0.2 9.5e-24 84.8 0.1 1.9 2 0 0 2 2 1 1 haloacid dehalogenase-like hydrolase AAA_17 PF13207.6 EAQ87080.1 - 8.7e-21 74.8 0.0 2.8e-20 73.1 0.0 2.0 1 0 0 1 1 1 1 AAA domain KAP_NTPase PF07693.14 EAQ87080.1 - 0.00021 20.6 0.0 0.00029 20.2 0.0 1.3 1 0 0 1 1 1 1 KAP family P-loop domain AAA_18 PF13238.6 EAQ87080.1 - 0.00023 21.7 0.0 0.0012 19.4 0.0 2.1 1 1 0 2 2 2 1 AAA domain Pribosyltran PF00156.27 EAQ87080.1 - 0.00033 20.2 0.5 0.0055 16.2 0.5 2.3 1 1 0 1 1 1 1 Phosphoribosyl transferase domain MeaB PF03308.16 EAQ87080.1 - 0.00052 19.1 0.1 0.0016 17.5 0.0 1.8 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_33 PF13671.6 EAQ87080.1 - 0.001 19.2 0.0 0.0027 17.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EAQ87080.1 - 0.0072 16.7 1.6 0.012 16.0 0.4 2.1 2 1 0 2 2 1 1 AAA ATPase domain Zeta_toxin PF06414.12 EAQ87080.1 - 0.01 15.1 0.0 0.025 13.9 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin AAA_24 PF13479.6 EAQ87080.1 - 0.015 15.0 0.0 0.038 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EAQ87080.1 - 0.016 15.1 0.0 0.043 13.7 0.0 1.7 1 0 0 1 1 1 0 NACHT domain NB-ARC PF00931.22 EAQ87080.1 - 0.017 14.3 0.0 0.03 13.5 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Viral_helicase1 PF01443.18 EAQ87080.1 - 0.027 14.2 0.0 0.057 13.1 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 EAQ87080.1 - 0.06 13.6 0.3 0.22 11.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain HAD_2 PF13419.6 EAQ87080.1 - 0.099 12.7 0.0 0.26 11.4 0.0 1.8 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase MMR_HSR1 PF01926.23 EAQ87080.1 - 0.12 12.4 0.1 1.1 9.3 0.0 2.6 3 0 0 3 3 3 0 50S ribosome-binding GTPase cobW PF02492.19 EAQ87080.1 - 0.14 11.7 0.0 0.33 10.5 0.0 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Thymidylate_kin PF02223.17 EAQ87080.1 - 0.19 11.4 0.1 9.4 5.9 0.0 2.4 2 0 0 2 2 2 0 Thymidylate kinase AA_permease_2 PF13520.6 EAQ87081.1 - 4.7e-36 124.5 49.4 2.8e-30 105.5 30.2 2.1 1 1 1 2 2 2 2 Amino acid permease AA_permease PF00324.21 EAQ87081.1 - 1.4e-16 60.2 51.3 1.6e-13 50.1 26.8 2.1 1 1 1 2 2 2 2 Amino acid permease OrsD PF12013.8 EAQ87081.1 - 3.5e-15 56.4 3.4 7e-08 32.9 0.0 3.5 3 0 0 3 3 3 2 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2H2_2 PF12756.7 EAQ87081.1 - 0.18 12.1 0.5 33 4.9 0.1 2.5 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) OrsD PF12013.8 EAQ87082.1 - 2.1e-14 53.9 0.8 2.5e-14 53.7 0.8 1.0 1 0 0 1 1 1 1 Orsellinic acid/F9775 biosynthesis cluster protein D Colicin_Pyocin PF01320.18 EAQ87084.1 - 0.3 11.2 5.3 1.7e+02 2.4 0.0 6.6 8 2 2 10 10 10 0 Colicin immunity protein / pyocin immunity protein FTA2 PF13095.6 EAQ87085.1 - 4.8e-68 229.0 0.0 6.7e-68 228.5 0.0 1.2 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Sigma70_r1_2 PF00140.20 EAQ87085.1 - 0.048 13.7 0.1 0.088 12.8 0.1 1.4 1 0 0 1 1 1 0 Sigma-70 factor, region 1.2 Glyco_hydro_3 PF00933.21 EAQ87087.1 - 2e-59 201.6 0.0 2.6e-59 201.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 EAQ87087.1 - 2.9e-53 180.8 0.0 4.7e-53 180.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 EAQ87087.1 - 2.3e-23 82.1 0.1 6.4e-23 80.7 0.1 1.8 1 0 0 1 1 1 1 Fibronectin type III-like domain Sugar-bind PF04198.13 EAQ87087.1 - 0.095 11.8 0.0 0.22 10.6 0.0 1.5 1 0 0 1 1 1 0 Putative sugar-binding domain Glyco_hydro_31 PF01055.26 EAQ87088.1 - 1.4e-109 367.2 0.3 1.8e-109 366.9 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 EAQ87088.1 - 5.7e-16 58.6 0.0 1.4e-15 57.3 0.0 1.7 1 0 0 1 1 1 1 Galactose mutarotase-like Sugar_tr PF00083.24 EAQ87089.1 - 4.9e-101 338.8 23.1 5.7e-101 338.6 23.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EAQ87089.1 - 4.6e-24 85.0 54.6 5.1e-23 81.6 29.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EAQ87089.1 - 8e-06 24.6 1.1 8e-06 24.6 1.1 1.8 3 0 0 3 3 3 1 Fungal trichothecene efflux pump (TRI12) DUF2530 PF10745.9 EAQ87089.1 - 0.08 13.2 4.1 0.39 11.0 0.8 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) Cutinase PF01083.22 EAQ87090.1 - 3.8e-22 79.1 0.0 5.1e-22 78.7 0.0 1.2 1 0 0 1 1 1 1 Cutinase VirJ PF06057.11 EAQ87090.1 - 0.016 15.1 0.0 0.027 14.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) PE-PPE PF08237.11 EAQ87090.1 - 0.076 12.5 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 PE-PPE domain DUF2974 PF11187.8 EAQ87090.1 - 0.13 11.8 0.0 0.17 11.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_1 PF00561.20 EAQ87090.1 - 0.18 11.4 0.0 0.19 11.4 0.0 1.1 1 0 0 1 1 1 0 alpha/beta hydrolase fold GRDP-like PF07173.12 EAQ87091.1 - 8.8e-18 65.3 11.6 5.6e-13 49.7 0.1 4.7 3 2 2 5 5 5 4 Glycine-rich domain-containing protein-like Ubiquitin_3 PF14836.6 EAQ87091.1 - 0.068 13.2 0.1 0.17 11.9 0.1 1.6 1 0 0 1 1 1 0 Ubiquitin-like domain Sporozoite_P67 PF05642.11 EAQ87091.1 - 0.22 9.6 2.2 0.29 9.2 2.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen E1-E2_ATPase PF00122.20 EAQ87093.1 - 7.3e-36 123.4 17.8 1.7e-29 102.6 0.1 3.9 5 0 0 5 5 5 2 E1-E2 ATPase Cation_ATPase PF13246.6 EAQ87093.1 - 3e-18 65.7 0.0 7.3e-18 64.4 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_C PF00689.21 EAQ87093.1 - 7e-18 65.0 12.1 2.4e-17 63.2 6.2 2.6 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EAQ87093.1 - 1.5e-17 64.6 0.0 3.8e-16 60.0 0.0 2.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EAQ87093.1 - 9.4e-15 54.1 0.1 2.5e-14 52.7 0.1 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EAQ87093.1 - 0.0026 17.5 0.4 0.0043 16.8 0.4 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase FliMN_C PF01052.20 EAQ87093.1 - 0.12 12.4 0.3 0.28 11.2 0.3 1.6 1 0 0 1 1 1 0 Type III flagellar switch regulator (C-ring) FliN C-term GMC_oxred_C PF05199.13 EAQ87094.1 - 1.7e-14 54.5 0.2 1.9e-14 54.4 0.2 1.0 1 0 0 1 1 1 1 GMC oxidoreductase RVT_3 PF13456.6 EAQ87095.1 - 0.0004 20.2 0.0 0.00082 19.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase-like zf-RVT PF13966.6 EAQ87095.1 - 0.0054 17.4 0.2 0.027 15.2 0.2 2.2 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Helitron_like_N PF14214.6 EAQ87096.1 - 6.3e-32 111.3 1.9 7.6e-32 111.1 0.5 1.8 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.14 EAQ87096.1 - 1.1e-25 90.6 0.0 1.3e-21 77.2 0.0 2.3 2 1 0 2 2 2 2 PIF1-like helicase CVNH PF08881.10 EAQ87096.1 - 6.8e-25 87.7 0.1 1.4e-24 86.7 0.1 1.6 1 0 0 1 1 1 1 CVNH domain AAA_30 PF13604.6 EAQ87096.1 - 1.2e-09 38.2 0.0 3e-09 36.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain Herpes_Helicase PF02689.14 EAQ87096.1 - 1.3e-05 23.4 0.0 2.8e-05 22.3 0.0 1.4 2 0 0 2 2 2 1 Helicase UvrD_C_2 PF13538.6 EAQ87096.1 - 0.00011 21.9 0.1 0.00027 20.7 0.1 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 EAQ87096.1 - 0.0011 19.3 0.0 0.0035 17.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 EAQ87096.1 - 0.15 11.8 0.0 19 4.9 0.0 2.6 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Rtt106 PF08512.12 EAQ87097.1 - 2.6e-29 101.4 0.0 7.6e-29 100.0 0.0 1.8 2 0 0 2 2 2 1 Histone chaperone Rttp106-like PH_18 PF18469.1 EAQ87097.1 - 0.0043 17.0 0.0 0.025 14.6 0.0 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain Cwf_Cwc_15 PF04889.12 EAQ87097.1 - 4.8 6.8 15.6 6.8 6.4 15.6 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein zf-C2H2 PF00096.26 EAQ87098.1 - 1.5 9.4 20.1 1.4 9.5 0.4 4.7 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EAQ87098.1 - 8.8 7.5 19.3 5.9 8.0 0.8 4.7 4 0 0 4 4 4 0 C2H2-type zinc finger DSPc PF00782.20 EAQ87099.1 - 2e-16 60.0 0.1 2.2e-09 37.2 0.1 3.0 2 1 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EAQ87099.1 - 0.0055 16.3 0.0 0.0092 15.6 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 EAQ87099.1 - 0.023 14.8 0.0 0.044 13.9 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate Init_tRNA_PT PF04179.12 EAQ87099.1 - 0.058 13.7 0.0 0.12 12.7 0.0 1.5 1 1 0 1 1 1 0 Rit1 DUSP-like domain Vfa1 PF08432.10 EAQ87100.1 - 9.8e-39 133.6 12.9 1.3e-38 133.2 12.9 1.1 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 MCM_bind PF09739.9 EAQ87100.1 - 0.11 10.9 5.9 0.13 10.7 5.9 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor RNA_pol_Rpc4 PF05132.14 EAQ87100.1 - 0.15 12.5 5.9 0.21 12.0 5.9 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF1168 PF06658.12 EAQ87100.1 - 0.3 10.9 22.6 0.42 10.4 22.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) DUF2052 PF09747.9 EAQ87100.1 - 0.56 10.3 14.0 0.76 9.9 14.0 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) RR_TM4-6 PF06459.12 EAQ87100.1 - 0.59 9.9 10.7 0.76 9.6 10.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 NPR3 PF03666.13 EAQ87100.1 - 0.8 8.4 10.0 0.99 8.1 10.0 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Afi1 PF07792.12 EAQ87100.1 - 0.8 10.2 10.3 1.2 9.7 10.3 1.3 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking PIEZO PF15917.5 EAQ87100.1 - 5.5 6.4 11.0 7.6 5.9 11.0 1.1 1 0 0 1 1 1 0 Piezo CDC45 PF02724.14 EAQ87100.1 - 8 4.6 14.4 9.5 4.4 14.4 1.0 1 0 0 1 1 1 0 CDC45-like protein TPR_2 PF07719.17 EAQ87101.1 - 9.1e-07 28.5 9.0 0.046 13.8 0.0 6.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 EAQ87101.1 - 5.7e-05 23.3 7.0 0.048 13.9 0.3 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 EAQ87101.1 - 0.092 13.3 0.1 0.092 13.3 0.1 3.6 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 EAQ87101.1 - 0.22 11.4 4.9 25 4.9 0.4 4.7 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_4 PF07721.14 EAQ87101.1 - 0.78 10.5 10.1 0.88 10.4 0.2 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 EAQ87101.1 - 1.6 9.8 7.9 30 5.8 0.3 4.6 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 EAQ87101.1 - 1.8 9.3 19.0 1.4 9.6 0.7 5.9 6 1 1 7 7 7 0 Tetratricopeptide repeat Sugar_tr PF00083.24 EAQ87103.1 - 3.5e-118 395.3 18.2 4e-118 395.1 18.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EAQ87103.1 - 3.2e-21 75.7 34.2 6.4e-21 74.7 30.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TPR_19 PF14559.6 EAQ87103.1 - 0.17 12.4 0.1 0.32 11.5 0.1 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat GDPD PF03009.17 EAQ87104.1 - 1e-14 54.9 0.0 1.3e-14 54.6 0.0 1.2 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family SET PF00856.28 EAQ87105.1 - 2.1e-10 41.3 0.1 5.1e-10 40.0 0.0 1.6 2 0 0 2 2 2 1 SET domain IPT PF01745.16 EAQ87105.1 - 0.0054 16.1 0.0 0.0075 15.7 0.0 1.2 1 0 0 1 1 1 1 Isopentenyl transferase Lambda_CIII PF02061.16 EAQ87105.1 - 0.17 12.0 0.0 0.34 11.0 0.0 1.5 1 0 0 1 1 1 0 Lambda Phage CIII FAD_binding_4 PF01565.23 EAQ87106.1 - 7.2e-22 77.6 6.1 2.5e-21 75.9 1.1 3.2 3 0 0 3 3 3 1 FAD binding domain BBE PF08031.12 EAQ87106.1 - 1.3e-12 47.6 0.1 2.4e-12 46.8 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like SH3_3 PF08239.11 EAQ87107.1 - 0.03 14.6 0.1 0.083 13.2 0.1 1.8 1 1 0 1 1 1 0 Bacterial SH3 domain RVT_1 PF00078.27 EAQ87108.1 - 2.7e-35 121.9 0.0 4.2e-35 121.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 EAQ87108.1 - 2.1e-23 82.4 0.0 4.3e-23 81.4 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 EAQ87108.1 - 6.2e-05 22.6 0.0 0.00013 21.6 0.0 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-CCHC PF00098.23 EAQ87108.1 - 0.00019 21.3 3.7 0.00041 20.3 3.7 1.6 1 0 0 1 1 1 1 Zinc knuckle GCSF PF16647.5 EAQ87108.1 - 0.17 11.7 0.0 0.43 10.4 0.0 1.6 1 0 0 1 1 1 0 Granulocyte colony-stimulating factor GST_N PF02798.20 EAQ87109.1 - 6.4e-17 61.7 0.0 1.1e-16 60.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EAQ87109.1 - 5.6e-13 49.1 0.0 1.2e-12 48.0 0.0 1.5 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EAQ87109.1 - 6.7e-13 48.7 0.0 1.1e-11 44.9 0.0 2.5 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EAQ87109.1 - 8.2e-11 42.0 0.0 2.5e-10 40.4 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EAQ87109.1 - 4.5e-10 39.4 0.0 8.6e-10 38.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EAQ87109.1 - 9.3e-09 35.4 0.0 2.1e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_5 PF18485.1 EAQ87109.1 - 0.045 14.1 0.0 0.09 13.1 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain NmrA PF05368.13 EAQ87110.1 - 0.003 17.1 0.0 0.012 15.2 0.0 1.8 1 1 1 2 2 2 1 NmrA-like family DCA16 PF15349.6 EAQ87110.1 - 0.038 13.5 0.1 0.07 12.7 0.1 1.3 1 0 0 1 1 1 0 DDB1- and CUL4-associated factor 16 Putative_PNPOx PF01243.20 EAQ87111.1 - 7.8e-06 26.0 0.0 1.4e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase SUKH_6 PF14568.6 EAQ87111.1 - 0.069 13.6 0.1 0.15 12.5 0.0 1.6 2 0 0 2 2 2 0 SMI1-KNR4 cell-wall adh_short PF00106.25 EAQ87112.1 - 2.1e-20 73.0 0.0 2.6e-20 72.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EAQ87112.1 - 1.3e-15 57.6 0.0 1.6e-15 57.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EAQ87112.1 - 6.2e-07 29.5 0.1 7.3e-07 29.3 0.1 1.1 1 0 0 1 1 1 1 KR domain DUF2263 PF10021.9 EAQ87113.1 - 6.1e-18 65.6 0.3 2.6e-17 63.6 0.3 2.1 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Herpes_UL32 PF06070.11 EAQ87113.1 - 5.1 4.7 10.0 6.6 4.3 10.0 1.1 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 APH PF01636.23 EAQ87114.1 - 4.5e-30 105.3 0.0 8.9e-30 104.4 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Abhydrolase_3 PF07859.13 EAQ87115.1 - 1.1e-35 123.4 0.0 1.4e-35 123.1 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 EAQ87115.1 - 0.022 13.6 0.0 0.032 13.1 0.0 1.1 1 0 0 1 1 1 0 Carboxylesterase family AAA PF00004.29 EAQ87116.1 - 1.8e-15 57.5 0.0 3.1e-15 56.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) SDA1 PF05285.12 EAQ87116.1 - 0.84 9.0 6.7 1.2 8.5 6.7 1.1 1 0 0 1 1 1 0 SDA1 Cwf_Cwc_15 PF04889.12 EAQ87116.1 - 1.3 8.7 5.9 1.8 8.3 5.9 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 EAQ87116.1 - 2.4 7.4 6.5 3.6 6.8 6.5 1.1 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.10 EAQ87116.1 - 2.5 8.5 10.8 5.1 7.6 10.8 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain GTA_holin_3TM PF11351.8 EAQ87117.1 - 3.1 8.4 4.6 17 6.0 0.2 2.4 2 0 0 2 2 2 0 Holin of 3TMs, for gene-transfer release DUF2781 PF10914.8 EAQ87118.1 - 9.8e-32 110.4 8.8 1.1e-31 110.2 8.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) Glyco_hydro_cc PF11790.8 EAQ87120.1 - 3.3e-69 233.1 0.0 4e-69 232.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Esterase PF00756.20 EAQ87121.1 - 9e-05 22.2 0.3 0.00026 20.7 0.1 1.9 1 1 1 2 2 2 1 Putative esterase RVT_1 PF00078.27 EAQ87121.1 - 0.003 17.1 0.0 0.0045 16.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Hydrolase_4 PF12146.8 EAQ87121.1 - 0.005 16.1 0.0 0.0078 15.5 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EAQ87121.1 - 0.0077 15.7 0.1 0.013 15.0 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Rad60-SLD_2 PF13881.6 EAQ87121.1 - 0.17 12.0 0.0 0.4 10.8 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Laminin_G_3 PF13385.6 EAQ87122.1 - 0.00027 21.1 0.1 0.00048 20.3 0.0 1.4 1 1 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily CBM_11 PF03425.13 EAQ87122.1 - 0.0017 18.2 0.0 0.0031 17.4 0.0 1.4 1 0 0 1 1 1 1 Carbohydrate binding domain (family 11) Polysacc_lyase PF14099.6 EAQ87122.1 - 0.026 14.4 0.2 0.099 12.5 0.1 1.9 1 1 0 2 2 2 0 Polysaccharide lyase PLDc_N PF13396.6 EAQ87123.1 - 3.3e-13 49.3 3.1 5.3e-13 48.7 3.1 1.4 1 0 0 1 1 1 1 Phospholipase_D-nuclease N-terminal DUF3976 PF13121.6 EAQ87123.1 - 0.012 15.8 1.3 0.012 15.8 1.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3976) DUF3951 PF13131.6 EAQ87123.1 - 0.21 11.8 2.7 0.74 10.1 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3951) DUF2207 PF09972.9 EAQ87123.1 - 0.68 8.6 2.3 0.61 8.8 2.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) ASFV_J13L PF05568.11 EAQ87123.1 - 5.6 6.7 4.5 9 6.0 0.8 2.1 1 1 1 2 2 2 0 African swine fever virus J13L protein TFIIA PF03153.13 EAQ87124.1 - 0.0044 17.1 14.8 0.22 11.4 2.5 2.2 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit MULE PF10551.9 EAQ87124.1 - 0.0048 17.3 0.0 0.013 15.9 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain Chromate_transp PF02417.15 EAQ87124.1 - 0.0085 16.2 3.2 0.026 14.7 2.9 1.9 1 1 0 1 1 1 1 Chromate transporter DUF3464 PF11947.8 EAQ87124.1 - 1 9.1 7.3 0.5 10.1 0.1 2.7 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 DUF4808 PF16066.5 EAQ87124.1 - 9.5 6.8 9.0 4 8.0 2.8 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4808) RVT_1 PF00078.27 EAQ87125.1 - 2.4e-33 115.5 0.0 5.6e-33 114.3 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 EAQ87125.1 - 7e-25 87.2 0.0 3e-24 85.2 0.0 2.2 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase zf-CCHC PF00098.23 EAQ87125.1 - 0.0091 16.0 2.5 0.0091 16.0 2.5 2.7 2 0 0 2 2 1 1 Zinc knuckle Herpes_UL6 PF01763.16 EAQ87125.1 - 0.025 13.1 1.4 0.055 12.0 1.4 1.5 1 0 0 1 1 1 0 Herpesvirus UL6 like Exo_endo_phos PF03372.23 EAQ87125.1 - 0.066 12.7 0.1 0.17 11.4 0.1 1.7 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family T3SSipB PF16535.5 EAQ87125.1 - 0.13 12.7 6.0 6.8 7.1 0.6 3.7 3 0 0 3 3 3 0 Type III cell invasion protein SipB SlyX PF04102.12 EAQ87125.1 - 0.19 12.4 6.6 1 10.0 6.5 2.5 1 1 0 1 1 1 0 SlyX DUF948 PF06103.11 EAQ87125.1 - 0.2 11.9 0.4 0.96 9.8 0.4 2.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) ADIP PF11559.8 EAQ87125.1 - 0.26 11.3 5.7 0.76 9.9 5.7 1.7 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding CASP_C PF08172.12 EAQ87125.1 - 6.7 6.0 12.3 0.45 9.8 3.0 2.8 3 0 0 3 3 3 0 CASP C terminal Jnk-SapK_ap_N PF09744.9 EAQ87125.1 - 7.5 6.8 9.1 1.1 9.5 3.0 2.4 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 ZapB PF06005.12 EAQ87125.1 - 9 6.8 10.2 30 5.1 10.2 1.9 1 0 0 1 1 1 0 Cell division protein ZapB FTA2 PF13095.6 EAQ87126.1 - 5.2e-66 222.4 0.0 6.7e-66 222.0 0.0 1.1 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Sigma70_r1_2 PF00140.20 EAQ87126.1 - 0.05 13.6 0.1 0.091 12.8 0.1 1.4 1 0 0 1 1 1 0 Sigma-70 factor, region 1.2 EB PF01683.18 EAQ87127.1 - 7.6e-05 22.9 28.6 0.23 11.8 5.6 3.3 3 0 0 3 3 3 3 EB module SesA PF17107.5 EAQ87129.1 - 3e-07 30.7 0.6 7e-07 29.5 0.3 1.8 2 0 0 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases Fib_alpha PF08702.10 EAQ87129.1 - 0.036 14.2 0.6 0.036 14.2 0.6 2.1 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family LMWPc PF01451.21 EAQ87129.1 - 0.11 12.9 0.0 16 5.9 0.0 2.5 2 1 0 2 2 2 0 Low molecular weight phosphotyrosine protein phosphatase FlxA PF14282.6 EAQ87129.1 - 4.9 7.2 5.5 5.3 7.1 1.9 2.5 2 1 1 3 3 3 0 FlxA-like protein Kinesin PF00225.23 EAQ87131.1 - 4.5e-47 160.6 0.0 9.9e-47 159.5 0.0 1.6 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EAQ87131.1 - 1.1e-08 35.2 0.0 1.9e-06 27.9 0.0 2.4 2 0 0 2 2 2 1 Microtubule binding EzrA PF06160.12 EAQ87131.1 - 0.026 12.7 0.8 0.036 12.2 0.8 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA NRBF2 PF08961.10 EAQ87131.1 - 0.053 13.1 0.6 0.13 11.9 0.6 1.6 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator Csm1_N PF18504.1 EAQ87131.1 - 2.5 8.5 4.1 24 5.3 0.5 2.4 2 0 0 2 2 2 0 Csm1 N-terminal domain PikAIV_N PF18605.1 EAQ87131.1 - 3.4 7.3 7.6 8.7 6.0 7.6 1.8 1 0 0 1 1 1 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain YabA PF06156.13 EAQ87131.1 - 3.8 8.2 5.4 9.5 6.9 0.1 2.7 2 1 1 3 3 3 0 Initiation control protein YabA PRKG1_interact PF15898.5 EAQ87131.1 - 4.4 8.3 11.4 4.1e+02 1.9 11.4 2.6 1 1 0 1 1 1 0 cGMP-dependent protein kinase interacting domain Jnk-SapK_ap_N PF09744.9 EAQ87131.1 - 7.6 6.7 12.5 2.3 8.5 7.0 2.1 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Ank_2 PF12796.7 EAQ87133.1 - 1.4e-44 150.6 0.0 4e-11 43.4 0.0 4.7 3 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAQ87133.1 - 3e-35 120.2 2.2 6.2e-07 29.9 0.1 6.0 3 2 3 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAQ87133.1 - 1.1e-31 108.4 1.3 5.6e-08 32.9 0.1 4.7 4 0 0 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAQ87133.1 - 1.3e-27 92.8 0.0 0.00019 21.6 0.0 8.7 8 0 0 8 8 8 4 Ankyrin repeat Ank PF00023.30 EAQ87133.1 - 1.4e-26 91.7 0.1 0.001 19.4 0.0 7.9 7 0 0 7 7 7 5 Ankyrin repeat NACHT PF05729.12 EAQ87133.1 - 2.6e-06 27.5 0.0 6.6e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EAQ87133.1 - 2.3e-05 24.9 0.1 0.00022 21.6 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EAQ87133.1 - 0.0025 18.1 0.1 0.01 16.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 EAQ87133.1 - 0.0034 16.6 0.0 0.006 15.8 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain zf-RVT PF13966.6 EAQ87134.1 - 0.016 15.9 0.0 0.055 14.2 0.0 1.9 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase CMD PF02627.20 EAQ87135.1 - 0.037 14.1 0.0 0.073 13.1 0.0 1.5 1 0 0 1 1 1 0 Carboxymuconolactone decarboxylase family Methyltransf_25 PF13649.6 EAQ87136.1 - 9.6e-16 58.3 0.0 2.1e-15 57.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EAQ87136.1 - 3.9e-15 56.3 0.0 1e-14 55.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EAQ87136.1 - 6.3e-12 46.1 0.0 1.1e-11 45.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAQ87136.1 - 4.3e-11 42.8 0.0 7.1e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EAQ87136.1 - 1.5e-06 28.1 0.0 4.7e-06 26.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.11 EAQ87136.1 - 0.027 13.4 0.0 0.042 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) RrnaAD PF00398.20 EAQ87136.1 - 0.16 11.0 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase MTS PF05175.14 EAQ87136.1 - 0.17 11.4 0.0 0.4 10.2 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase small domain NmrA PF05368.13 EAQ87137.1 - 1.7e-18 67.0 0.0 2.2e-18 66.7 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EAQ87137.1 - 2.5e-12 47.1 0.0 5.3e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 EAQ87137.1 - 0.00023 21.4 0.0 0.00046 20.4 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 EAQ87137.1 - 0.038 14.4 0.0 0.071 13.5 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.21 EAQ87137.1 - 0.052 13.0 0.0 0.081 12.4 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family ApbA PF02558.16 EAQ87137.1 - 0.061 13.0 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA GutM PF06923.11 EAQ87138.1 - 0.14 12.3 0.2 0.6 10.2 0.0 1.9 2 0 0 2 2 2 0 Glucitol operon activator protein (GutM) SNF2_N PF00176.23 EAQ87139.1 - 3.7e-49 167.3 0.0 5.5e-49 166.8 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain NB-ARC PF00931.22 EAQ87140.1 - 0.00052 19.3 0.0 0.0011 18.2 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain KAP_NTPase PF07693.14 EAQ87140.1 - 0.0039 16.5 0.1 0.27 10.4 0.0 2.3 2 0 0 2 2 2 1 KAP family P-loop domain AAA_16 PF13191.6 EAQ87140.1 - 0.0076 16.6 0.0 0.034 14.5 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 EAQ87140.1 - 0.023 14.2 0.0 0.044 13.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_11 PF13086.6 EAQ87140.1 - 0.04 13.7 1.1 0.082 12.7 0.0 2.1 3 0 0 3 3 3 0 AAA domain DAP3 PF10236.9 EAQ87140.1 - 0.055 12.6 0.0 0.12 11.6 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 RNA_helicase PF00910.22 EAQ87140.1 - 0.056 13.8 0.0 0.18 12.2 0.0 1.9 1 0 0 1 1 1 0 RNA helicase DUF2075 PF09848.9 EAQ87140.1 - 0.11 11.7 0.0 0.23 10.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_33 PF13671.6 EAQ87140.1 - 0.12 12.5 2.6 9 6.4 0.0 3.5 4 0 0 4 4 4 0 AAA domain HET PF06985.11 EAQ87141.1 - 2.8e-39 134.8 1.5 4.3e-39 134.2 1.5 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Tannase PF07519.11 EAQ87142.1 - 1.1e-81 275.2 0.0 1.4e-81 274.8 0.0 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Hydrolase_4 PF12146.8 EAQ87142.1 - 0.0012 18.1 0.0 0.91 8.7 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EAQ87142.1 - 0.0014 18.1 0.1 1.2 8.5 0.1 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 EAQ87142.1 - 0.0074 16.0 0.2 0.021 14.5 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Kei1 PF08552.11 EAQ87144.1 - 1.5e-56 191.3 4.4 2e-56 190.9 4.4 1.2 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 Oxidored_q3 PF00499.20 EAQ87144.1 - 0.001 18.8 1.8 0.0018 18.0 1.8 1.4 1 1 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 SPC12 PF06645.13 EAQ87144.1 - 0.031 14.4 1.6 0.031 14.4 1.6 2.9 3 0 0 3 3 3 0 Microsomal signal peptidase 12 kDa subunit (SPC12) NIR_SIR PF01077.22 EAQ87145.1 - 3e-56 189.3 0.1 1.2e-49 167.9 0.0 2.5 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 EAQ87145.1 - 1.9e-32 110.9 0.0 1.9e-16 59.6 0.0 2.6 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.25 EAQ87145.1 - 1.1e-29 103.5 0.0 2.3e-29 102.4 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin POR_N PF01855.19 EAQ87145.1 - 6.5e-08 32.6 0.1 2.1e-07 30.9 0.0 1.9 2 0 0 2 2 2 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Chitin_synth_1 PF01644.17 EAQ87146.1 - 5.7e-66 221.5 0.3 7.9e-66 221.0 0.3 1.1 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.15 EAQ87146.1 - 0.006 15.2 0.0 0.013 14.2 0.0 1.4 1 0 0 1 1 1 1 Chitin synthase MARVEL PF01284.23 EAQ87147.1 - 2.3e-27 95.8 1.5 2.8e-27 95.5 1.5 1.1 1 0 0 1 1 1 1 Membrane-associating domain Amastin PF07344.11 EAQ87147.1 - 0.14 12.0 1.5 0.26 11.1 1.5 1.5 1 0 0 1 1 1 0 Amastin surface glycoprotein DUF1077 PF06417.12 EAQ87148.1 - 1.1e-08 35.1 3.0 2.2e-07 30.9 0.2 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF1077) Adaptin_N PF01602.20 EAQ87149.1 - 2e-124 416.1 5.8 2.5e-124 415.7 5.8 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EAQ87149.1 - 3.9e-55 186.3 7.7 9.4e-55 185.1 0.0 3.6 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EAQ87149.1 - 3.3e-16 59.4 5.8 1.2e-08 35.2 0.1 5.0 4 1 0 4 4 4 3 HEAT repeats HEAT PF02985.22 EAQ87149.1 - 1.5e-11 43.5 3.0 0.00012 22.0 0.0 5.7 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.6 EAQ87149.1 - 2.6e-05 24.6 2.7 5 7.7 0.0 6.4 6 0 0 6 6 6 1 HEAT-like repeat CLASP_N PF12348.8 EAQ87149.1 - 9e-05 22.1 1.3 0.057 13.0 0.0 3.2 3 0 0 3 3 3 2 CLASP N terminal RTP1_C1 PF10363.9 EAQ87149.1 - 0.0019 18.3 1.2 0.12 12.6 0.1 3.4 2 1 1 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 Arm PF00514.23 EAQ87149.1 - 0.002 18.1 1.2 6.5 7.0 0.0 4.5 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 EAQ87149.1 - 0.021 14.8 0.5 3.5 7.7 0.0 4.2 5 1 0 5 5 5 0 Spinocerebellar ataxia type 10 protein domain DNA_alkylation PF08713.11 EAQ87149.1 - 0.11 12.2 0.1 4.5 6.9 0.0 3.1 2 2 1 3 3 3 0 DNA alkylation repair enzyme NDC10_II PF16787.5 EAQ87150.1 - 1.1e-51 175.8 0.0 1.5e-51 175.3 0.0 1.1 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 GCR1_C PF12550.8 EAQ87150.1 - 3.5e-19 68.9 0.2 8.2e-19 67.7 0.1 1.6 2 0 0 2 2 2 1 Transcriptional activator of glycolytic enzymes AAA PF00004.29 EAQ87151.1 - 1.9e-13 51.0 0.0 2.7e-13 50.5 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EAQ87151.1 - 9.9e-06 26.0 0.2 6.9e-05 23.3 0.0 2.1 1 1 2 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 EAQ87151.1 - 0.00018 21.8 0.1 0.0033 17.7 0.0 2.2 1 1 1 2 2 2 1 AAA domain CPT PF07931.12 EAQ87151.1 - 0.0004 20.3 0.0 0.0012 18.7 0.0 1.7 1 1 1 2 2 2 1 Chloramphenicol phosphotransferase-like protein RuvB_N PF05496.12 EAQ87151.1 - 0.0024 17.6 0.0 0.0032 17.2 0.0 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 EAQ87151.1 - 0.0027 17.7 0.0 0.0072 16.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Hydin_ADK PF17213.3 EAQ87151.1 - 0.016 15.5 0.0 0.03 14.6 0.0 1.4 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Torsin PF06309.11 EAQ87151.1 - 0.069 13.2 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Torsin AAA_18 PF13238.6 EAQ87151.1 - 0.07 13.7 0.0 0.11 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EAQ87151.1 - 0.08 12.7 0.0 0.17 11.6 0.0 1.4 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EAQ87151.1 - 0.082 12.2 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Sigma54_activat PF00158.26 EAQ87151.1 - 0.11 12.2 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_19 PF13245.6 EAQ87151.1 - 0.13 12.6 0.0 0.22 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 EAQ87151.1 - 0.13 11.4 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_3 PF07726.11 EAQ87151.1 - 0.15 11.9 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 EAQ87151.1 - 0.15 11.7 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain PIF1 PF05970.14 EAQ87154.1 - 6e-41 140.8 0.0 1.5e-26 93.4 0.0 2.7 2 1 1 3 3 3 2 PIF1-like helicase AAA_30 PF13604.6 EAQ87154.1 - 7.3e-22 78.0 0.0 7.5e-20 71.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EAQ87154.1 - 1.8e-13 51.0 0.0 4.7e-13 49.7 0.0 1.7 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 EAQ87154.1 - 2.1e-05 24.5 0.1 0.072 13.0 0.1 2.3 2 0 0 2 2 2 2 NTPase MeaB PF03308.16 EAQ87154.1 - 0.0018 17.3 0.0 0.0029 16.6 0.0 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 EAQ87154.1 - 0.011 16.0 0.1 0.035 14.4 0.1 1.8 1 1 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 EAQ87154.1 - 0.017 14.8 0.1 0.052 13.3 0.0 1.8 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_29 PF13555.6 EAQ87154.1 - 0.02 14.7 0.0 0.046 13.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 EAQ87154.1 - 0.02 14.9 0.0 0.07 13.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EAQ87154.1 - 0.022 15.2 0.0 0.052 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.14 EAQ87154.1 - 0.034 14.1 0.2 0.093 12.7 0.2 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Helicase_RecD PF05127.14 EAQ87154.1 - 0.061 13.2 1.5 0.13 12.1 0.5 2.1 2 1 0 2 2 2 0 Helicase AAA_18 PF13238.6 EAQ87154.1 - 0.081 13.5 0.0 0.2 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 EAQ87154.1 - 0.081 13.4 0.1 0.43 11.0 0.0 2.2 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 EAQ87154.1 - 0.11 11.8 0.1 0.21 10.9 0.1 1.4 1 0 0 1 1 1 0 Zeta toxin APS_kinase PF01583.20 EAQ87154.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase Mg_chelatase PF01078.21 EAQ87154.1 - 0.16 11.3 0.0 0.34 10.2 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PIF1 PF05970.14 EAQ87155.1 - 1e-39 136.7 0.0 1.4e-24 87.0 0.0 2.6 2 1 1 3 3 3 2 PIF1-like helicase AAA_30 PF13604.6 EAQ87155.1 - 6.8e-22 78.1 0.0 1.6e-20 73.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EAQ87155.1 - 3.5e-12 46.9 0.0 8.4e-12 45.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 EAQ87155.1 - 0.00018 21.5 0.1 0.067 13.1 0.0 2.6 2 0 0 2 2 2 1 NTPase MeaB PF03308.16 EAQ87155.1 - 0.0032 16.5 0.8 0.0048 15.9 0.0 1.6 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB DZR PF12773.7 EAQ87155.1 - 0.0071 16.3 1.5 0.016 15.2 1.5 1.6 1 0 0 1 1 1 1 Double zinc ribbon APS_kinase PF01583.20 EAQ87155.1 - 0.014 15.2 0.0 0.031 14.2 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_16 PF13191.6 EAQ87155.1 - 0.017 15.5 0.2 0.11 12.9 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 EAQ87155.1 - 0.019 15.3 0.2 0.091 13.0 0.0 2.2 2 1 0 2 2 1 0 AAA domain DUF1610 PF07754.11 EAQ87155.1 - 0.029 14.3 3.5 0.095 12.7 3.5 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1610) AAA_18 PF13238.6 EAQ87155.1 - 0.038 14.5 0.3 0.2 12.2 0.0 2.4 3 0 0 3 3 2 0 AAA domain AAA_29 PF13555.6 EAQ87155.1 - 0.042 13.6 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain UvrD_C_2 PF13538.6 EAQ87155.1 - 0.046 13.5 0.0 0.27 11.1 0.0 2.3 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain Zeta_toxin PF06414.12 EAQ87155.1 - 0.05 12.9 0.1 0.17 11.1 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin RNA_POL_M_15KD PF02150.16 EAQ87155.1 - 0.06 13.2 0.5 0.12 12.3 0.5 1.5 1 0 0 1 1 1 0 RNA polymerases M/15 Kd subunit Viral_helicase1 PF01443.18 EAQ87155.1 - 0.069 12.9 0.3 0.39 10.4 0.2 2.3 2 1 0 2 2 2 0 Viral (Superfamily 1) RNA helicase DNA_ligase_ZBD PF03119.16 EAQ87155.1 - 0.14 12.2 3.0 0.4 10.8 3.0 1.8 1 0 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain AAA_7 PF12775.7 EAQ87155.1 - 0.19 11.3 0.1 2.1 7.8 0.0 2.5 3 0 0 3 3 3 0 P-loop containing dynein motor region zf-RING_4 PF14570.6 EAQ87155.1 - 0.26 11.1 1.4 0.53 10.1 1.4 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-TFIIB PF13453.6 EAQ87155.1 - 0.37 10.1 3.5 0.8 9.1 3.5 1.6 1 0 0 1 1 1 0 Transcription factor zinc-finger Rad60-SLD_2 PF13881.6 EAQ87156.1 - 3.9e-12 46.2 0.0 6.4e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EAQ87156.1 - 0.00015 21.5 0.0 0.0003 20.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 EAQ87156.1 - 0.00047 20.7 0.0 0.001 19.6 0.0 1.5 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain UMP1 PF05348.11 EAQ87157.1 - 1.1e-41 141.7 0.0 1.4e-41 141.5 0.0 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 ABC_tran PF00005.27 EAQ87158.1 - 1.2e-14 55.0 0.0 1.5e-09 38.5 0.0 3.2 2 1 0 2 2 2 2 ABC transporter SbcCD_C PF13558.6 EAQ87158.1 - 1.4e-06 28.4 0.1 0.0019 18.4 0.1 2.4 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.6 EAQ87158.1 - 0.00019 21.3 0.9 0.085 12.6 0.4 2.4 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system PduV-EutP PF10662.9 EAQ87158.1 - 0.048 13.4 0.0 0.084 12.6 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.6 EAQ87158.1 - 0.059 13.6 0.1 13 6.0 0.0 2.7 3 0 0 3 3 3 0 AAA domain ApbA_C PF08546.11 EAQ87159.1 - 1.5e-36 125.4 0.1 2.3e-36 124.8 0.1 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 EAQ87159.1 - 4.5e-27 94.6 0.0 2.5e-26 92.1 0.0 2.0 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ExoD PF06055.12 EAQ87160.1 - 0.12 11.7 0.1 0.14 11.5 0.1 1.2 1 0 0 1 1 1 0 Exopolysaccharide synthesis, ExoD Ribosomal_L24e PF01246.20 EAQ87161.1 - 1.2e-27 95.9 6.7 1.2e-27 95.9 6.7 1.6 2 0 0 2 2 2 1 Ribosomal protein L24e Ras PF00071.22 EAQ87162.1 - 1.2e-41 142.1 0.1 1.5e-41 141.7 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAQ87162.1 - 7.2e-21 74.6 0.1 1.2e-20 73.9 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAQ87162.1 - 2.2e-11 43.5 0.5 2.8e-11 43.2 0.5 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EAQ87162.1 - 1.5e-05 24.6 0.1 3.4e-05 23.5 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain TIR_2 PF13676.6 EAQ87162.1 - 0.019 15.5 0.1 0.034 14.8 0.1 1.3 1 0 0 1 1 1 0 TIR domain FlgH PF02107.16 EAQ87162.1 - 0.021 14.5 0.3 0.027 14.1 0.3 1.2 1 0 0 1 1 1 0 Flagellar L-ring protein Gtr1_RagA PF04670.12 EAQ87162.1 - 0.037 13.4 0.1 0.048 13.0 0.1 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region TetR_C_16 PF17920.1 EAQ87162.1 - 0.058 13.6 0.1 0.31 11.3 0.0 1.9 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain ATP_bind_1 PF03029.17 EAQ87162.1 - 0.069 12.9 0.0 0.084 12.6 0.0 1.1 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Nop53 PF07767.11 EAQ87163.1 - 2.4e-84 284.0 40.8 4.8e-48 164.5 32.5 2.0 1 1 1 2 2 2 2 Nop53 (60S ribosomal biogenesis) DUF2259 PF10016.9 EAQ87163.1 - 0.58 10.1 6.1 1.5 8.7 1.8 2.6 2 1 0 3 3 3 0 Predicted secreted protein (DUF2259) adh_short PF00106.25 EAQ87164.1 - 7.8e-25 87.5 0.1 2.7e-23 82.5 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EAQ87164.1 - 2.7e-15 56.6 0.0 5.2e-15 55.6 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EAQ87164.1 - 5.5e-09 36.2 0.0 9.3e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 EAQ87164.1 - 0.0068 15.8 0.1 0.018 14.5 0.0 1.6 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EAQ87164.1 - 0.028 13.9 0.1 0.044 13.2 0.1 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF547 PF04784.14 EAQ87164.1 - 0.18 11.9 0.0 0.28 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF547 Glyco_hydro_61 PF03443.14 EAQ87165.1 - 2.2e-29 102.9 0.0 2.7e-29 102.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 NACHT_N PF17100.5 EAQ87166.1 - 4.6e-08 33.2 0.1 2.1e-07 31.0 0.1 2.1 2 0 0 2 2 2 1 N-terminal domain of NWD NACHT-NTPase AAA_22 PF13401.6 EAQ87166.1 - 6.8e-06 26.4 0.0 2.3e-05 24.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 EAQ87166.1 - 9e-06 25.7 0.0 2.2e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EAQ87166.1 - 1.7e-05 25.3 0.0 4.3e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain MatE PF01554.18 EAQ87166.1 - 0.0064 16.2 7.3 0.61 9.7 7.3 2.7 1 1 0 1 1 1 1 MatE TsaE PF02367.17 EAQ87166.1 - 0.0087 16.1 0.0 0.027 14.5 0.0 1.8 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE NB-ARC PF00931.22 EAQ87166.1 - 0.055 12.7 0.2 0.15 11.2 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain U3_snoRNA_assoc PF08297.11 EAQ87166.1 - 0.2 12.4 1.4 11 6.8 0.0 3.4 3 0 0 3 3 3 0 U3 snoRNA associated Glyco_hydro_12 PF01670.16 EAQ87167.1 - 4.4e-70 236.0 13.1 5e-70 235.8 13.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 Glyco_hydro_3_C PF01915.22 EAQ87168.1 - 6.3e-31 107.9 0.3 3.1e-29 102.4 0.3 2.2 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EAQ87168.1 - 7.1e-16 58.5 0.0 1.2e-15 57.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Pyr_redox_2 PF07992.14 EAQ87169.1 - 2.5e-45 155.0 0.0 3.9e-45 154.3 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EAQ87169.1 - 2.4e-15 56.8 0.0 1.2e-10 41.8 0.0 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.32 EAQ87169.1 - 7.9e-07 28.2 0.1 2.3e-06 26.8 0.1 1.8 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 EAQ87169.1 - 2.2e-05 24.0 0.3 7.4e-05 22.4 0.3 1.9 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 EAQ87169.1 - 4.5e-05 23.8 0.1 0.00012 22.5 0.1 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 EAQ87169.1 - 0.0039 16.6 0.3 0.0088 15.5 0.3 1.6 1 0 0 1 1 1 1 EF hand FAD_binding_2 PF00890.24 EAQ87169.1 - 0.027 13.5 0.1 1.2 8.1 0.1 2.8 3 0 0 3 3 3 0 FAD binding domain NAD_binding_8 PF13450.6 EAQ87169.1 - 0.052 13.8 0.0 1.1 9.6 0.0 2.7 2 1 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EAQ87169.1 - 0.085 12.1 0.3 2.1 7.5 0.3 2.7 2 2 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase PRK PF00485.18 EAQ87170.1 - 3.6e-57 193.3 0.0 4.9e-57 192.9 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.6 EAQ87170.1 - 5.6e-37 127.2 0.0 8.5e-37 126.6 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AAA_18 PF13238.6 EAQ87170.1 - 4.8e-05 23.9 0.0 0.0001 22.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain CPT PF07931.12 EAQ87170.1 - 0.00015 21.7 0.0 0.00054 19.8 0.0 2.0 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.6 EAQ87170.1 - 0.00024 21.3 0.0 0.0013 18.9 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 EAQ87170.1 - 0.00067 20.1 0.3 0.0051 17.3 0.3 2.3 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 EAQ87170.1 - 0.005 17.4 0.1 0.014 15.9 0.0 1.8 2 0 0 2 2 2 1 ABC transporter AAA_29 PF13555.6 EAQ87170.1 - 0.011 15.4 0.1 0.052 13.3 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 EAQ87170.1 - 0.012 14.9 0.0 0.024 13.9 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin NB-ARC PF00931.22 EAQ87170.1 - 0.016 14.4 0.0 0.032 13.4 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Cytidylate_kin PF02224.18 EAQ87170.1 - 0.018 14.8 0.1 0.37 10.5 0.0 2.3 2 0 0 2 2 2 0 Cytidylate kinase AAA_24 PF13479.6 EAQ87170.1 - 0.02 14.6 0.0 0.051 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.17 EAQ87170.1 - 0.05 13.7 0.1 0.13 12.3 0.0 1.7 2 0 0 2 2 2 0 Helicase HerA, central domain dNK PF01712.19 EAQ87170.1 - 0.066 13.1 0.0 0.23 11.3 0.0 1.8 1 1 0 1 1 1 0 Deoxynucleoside kinase RsgA_GTPase PF03193.16 EAQ87170.1 - 0.12 12.3 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase DUF815 PF05673.13 EAQ87170.1 - 0.16 11.1 0.1 5.8 6.0 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) CLTH PF10607.9 EAQ87171.1 - 1.2e-33 116.1 0.1 1.8e-33 115.5 0.1 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 EAQ87171.1 - 5.8e-09 35.6 0.0 1.8e-08 34.0 0.0 1.9 2 0 0 2 2 2 1 LisH ETC_C1_NDUFA4 PF04800.12 EAQ87172.1 - 4.3e-36 123.1 0.4 6.8e-36 122.4 0.4 1.3 1 0 0 1 1 1 1 ETC complex I subunit conserved region F1F0-ATPsyn_F PF10791.9 EAQ87173.1 - 2.8e-39 133.5 2.4 4e-39 133.0 0.6 2.2 2 0 0 2 2 2 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi Aminotran_1_2 PF00155.21 EAQ87174.1 - 1.4e-09 37.6 0.0 4.4e-08 32.7 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class I and II RNase_H2_suC PF08615.11 EAQ87175.1 - 1.8e-24 86.6 0.0 1.5e-23 83.6 0.0 1.9 1 1 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) CMAS PF02353.20 EAQ87176.1 - 2.7e-12 46.6 0.0 2.9e-08 33.3 0.0 2.2 2 0 0 2 2 2 2 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 EAQ87176.1 - 0.013 15.3 0.0 0.024 14.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain RNase_T PF00929.24 EAQ87177.1 - 4.8e-13 50.0 0.0 1.2e-12 48.7 0.0 1.6 1 1 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 EAQ87177.1 - 0.013 15.2 0.0 0.025 14.3 0.0 1.5 1 1 0 1 1 1 0 3'-5' exonuclease Ndc1_Nup PF09531.10 EAQ87177.1 - 0.18 10.5 1.1 0.18 10.4 1.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup ORC6 PF05460.13 EAQ87177.1 - 5.6 6.1 10.4 7.7 5.7 10.4 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) CD99L2 PF12301.8 EAQ87179.1 - 0.0047 17.2 0.4 0.0094 16.3 0.4 1.5 1 0 0 1 1 1 1 CD99 antigen like protein 2 Clr5 PF14420.6 EAQ87181.1 - 3.2e-11 43.3 0.9 6.4e-11 42.3 0.9 1.4 1 0 0 1 1 1 1 Clr5 domain MOZ_SAS PF01853.18 EAQ87183.1 - 1.6e-80 268.9 0.3 3e-80 268.1 0.3 1.4 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 EAQ87183.1 - 1.2e-22 79.3 1.2 2.2e-22 78.4 1.2 1.5 1 0 0 1 1 1 1 MYST family zinc finger domain Tudor-knot PF11717.8 EAQ87183.1 - 2.7e-18 65.6 1.0 3e-17 62.3 0.0 2.7 3 0 0 3 3 3 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 EAQ87183.1 - 0.00024 21.5 0.0 0.00049 20.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EAQ87183.1 - 0.0061 16.8 0.0 0.014 15.7 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family DDRGK PF09756.9 EAQ87183.1 - 0.53 9.9 0.0 0.53 9.9 0.0 3.0 4 0 0 4 4 4 0 DDRGK domain MCM PF00493.23 EAQ87184.1 - 2.1e-104 347.5 0.2 3.4e-104 346.8 0.2 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EAQ87184.1 - 1.7e-38 131.3 0.2 3.6e-38 130.2 0.2 1.5 1 0 0 1 1 1 1 MCM OB domain MCM6_C PF18263.1 EAQ87184.1 - 9.4e-33 112.7 0.0 1.7e-32 111.8 0.0 1.5 1 0 0 1 1 1 1 MCM6 C-terminal winged-helix domain MCM_lid PF17855.1 EAQ87184.1 - 6.8e-25 87.3 0.9 3e-24 85.2 0.1 2.5 3 0 0 3 3 3 1 MCM AAA-lid domain MCM_N PF14551.6 EAQ87184.1 - 7.5e-22 77.9 0.0 2.1e-21 76.5 0.0 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 EAQ87184.1 - 1.9e-07 30.7 0.0 4.4e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 EAQ87184.1 - 0.0011 18.7 0.0 0.0023 17.7 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.11 EAQ87184.1 - 0.0012 18.7 0.0 0.003 17.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EAQ87184.1 - 0.023 14.7 0.0 0.057 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Polysacc_deac_1 PF01522.21 EAQ87185.1 - 1.1e-16 60.9 0.0 1.9e-16 60.1 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase AAA_29 PF13555.6 EAQ87185.1 - 0.12 12.1 1.1 0.29 10.9 1.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain TRAPPC-Trs85 PF12739.7 EAQ87187.1 - 6.6e-117 390.9 0.3 1e-116 390.2 0.3 1.3 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit GRIP PF01465.20 EAQ87189.1 - 0.033 14.1 0.1 0.063 13.2 0.1 1.5 1 0 0 1 1 1 0 GRIP domain zf-C3HC4_2 PF13923.6 EAQ87190.1 - 7.5e-10 38.5 16.8 9e-10 38.2 13.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) SAP PF02037.27 EAQ87190.1 - 3.1e-07 30.0 0.1 5.5e-07 29.2 0.1 1.4 1 0 0 1 1 1 1 SAP domain zf-C3HC4 PF00097.25 EAQ87190.1 - 5.5e-06 26.1 14.2 5.5e-06 26.1 14.2 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EAQ87190.1 - 3.2e-05 23.8 12.0 3.2e-05 23.8 12.0 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EAQ87190.1 - 3.6e-05 23.5 11.3 3.6e-05 23.5 11.3 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) U-box PF04564.15 EAQ87190.1 - 9.9e-05 22.4 0.0 0.00024 21.2 0.0 1.7 1 0 0 1 1 1 1 U-box domain zf-RING_5 PF14634.6 EAQ87190.1 - 0.00011 22.0 13.1 0.00011 22.0 13.1 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_6 PF14835.6 EAQ87190.1 - 0.00027 20.7 6.1 0.00027 20.7 6.1 2.1 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-RING_2 PF13639.6 EAQ87190.1 - 0.0008 19.7 20.1 0.0011 19.3 14.4 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.6 EAQ87190.1 - 0.0038 17.3 13.9 0.0038 17.3 13.9 2.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 EAQ87190.1 - 0.0061 16.4 14.3 0.05 13.5 11.8 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 EAQ87190.1 - 0.0063 16.6 5.6 0.012 15.7 5.6 1.5 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-rbx1 PF12678.7 EAQ87190.1 - 0.0094 16.2 8.4 0.0094 16.2 8.4 1.9 2 0 0 2 2 2 1 RING-H2 zinc finger domain Mob_synth_C PF06463.13 EAQ87190.1 - 0.012 15.6 3.8 0.026 14.4 3.8 1.5 1 0 0 1 1 1 0 Molybdenum Cofactor Synthesis C zf-ANAPC11 PF12861.7 EAQ87190.1 - 0.37 10.9 4.4 0.58 10.2 3.3 1.9 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger INCENP_ARK-bind PF03941.15 EAQ87191.1 - 1.8e-19 69.4 0.8 1.8e-19 69.4 0.8 2.5 2 0 0 2 2 2 1 Inner centromere protein, ARK binding region DnaJ PF00226.31 EAQ87192.1 - 9.6e-18 64.1 1.0 2e-17 63.1 1.0 1.6 1 0 0 1 1 1 1 DnaJ domain PDZ_1 PF12812.7 EAQ87193.1 - 3.3e-54 180.8 0.0 9e-34 115.4 0.0 2.5 2 0 0 2 2 2 2 PDZ-like domain Trypsin_2 PF13365.6 EAQ87193.1 - 1.1e-26 94.6 0.7 9.9e-22 78.4 0.0 2.5 2 0 0 2 2 2 2 Trypsin-like peptidase domain PDZ_2 PF13180.6 EAQ87193.1 - 2e-12 47.2 0.3 0.0005 20.3 0.0 4.4 4 0 0 4 4 4 3 PDZ domain PDZ_6 PF17820.1 EAQ87193.1 - 1.4e-11 44.0 0.0 0.00055 19.7 0.0 3.8 3 0 0 3 3 3 3 PDZ domain PDZ PF00595.24 EAQ87193.1 - 5.3e-07 29.9 0.0 0.024 15.0 0.0 3.9 3 0 0 3 3 3 2 PDZ domain Trypsin PF00089.26 EAQ87193.1 - 0.00065 19.6 0.0 0.0021 17.9 0.0 1.8 1 1 0 1 1 1 1 Trypsin Tricorn_PDZ PF14685.6 EAQ87193.1 - 0.012 15.6 0.3 5.5 7.0 0.0 3.9 4 0 0 4 4 4 0 Tricorn protease PDZ domain Peptidase_S46 PF10459.9 EAQ87193.1 - 0.068 11.8 0.1 0.12 11.0 0.1 1.3 1 0 0 1 1 1 0 Peptidase S46 4HPAD_g_N PF18671.1 EAQ87193.1 - 0.071 12.8 0.0 0.22 11.3 0.0 1.9 1 0 0 1 1 1 0 4-Hydroxyphenylacetate decarboxylase subunit gamma N-terminal Avl9 PF09794.9 EAQ87194.1 - 1.5e-124 415.6 0.0 3.4e-68 230.1 0.0 2.2 1 1 1 2 2 2 2 Transport protein Avl9 SPA PF08616.10 EAQ87194.1 - 0.00044 20.2 0.0 0.00075 19.4 0.0 1.3 1 0 0 1 1 1 1 Stabilization of polarity axis DUF2347 PF09804.9 EAQ87194.1 - 0.17 11.4 0.0 0.17 11.4 0.0 3.2 4 1 0 4 4 4 0 Uncharacterized conserved protein (DUF2347) Pkinase PF00069.25 EAQ87195.1 - 1.6e-68 230.9 0.0 2e-68 230.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ87195.1 - 4.9e-32 111.2 0.0 6.3e-32 110.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EAQ87195.1 - 6.6e-06 25.3 0.1 8.9e-06 24.9 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EAQ87195.1 - 5.1e-05 22.7 0.1 0.00016 21.1 0.1 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EAQ87195.1 - 0.00075 19.5 0.0 0.0017 18.3 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EAQ87195.1 - 0.0031 16.9 0.2 0.045 13.0 0.0 2.3 2 1 1 3 3 3 1 Kinase-like RIO1 PF01163.22 EAQ87195.1 - 0.021 14.5 0.0 0.035 13.7 0.0 1.4 1 0 0 1 1 1 0 RIO1 family FTA2 PF13095.6 EAQ87195.1 - 0.026 14.2 0.0 0.046 13.3 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Phosphorylase PF00343.20 EAQ87196.1 - 0 1046.7 0.0 0 1046.5 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase G-alpha PF00503.20 EAQ87197.1 - 3.1e-115 385.1 0.3 3.6e-115 384.9 0.3 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EAQ87197.1 - 7.1e-16 58.2 0.6 5.1e-10 39.1 0.1 2.6 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EAQ87197.1 - 0.00025 20.5 1.8 0.096 12.0 1.8 2.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 EAQ87197.1 - 0.0031 17.7 1.1 1.2 9.4 0.1 2.8 2 1 1 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 EAQ87197.1 - 0.11 12.3 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Cullin PF00888.22 EAQ87198.1 - 9.5e-168 559.6 11.5 5.6e-164 547.1 11.5 3.2 1 1 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 EAQ87198.1 - 1.5e-25 89.0 5.0 4.7e-25 87.4 5.0 1.9 1 0 0 1 1 1 1 Cullin protein neddylation domain Rrf2 PF02082.20 EAQ87198.1 - 0.03 14.7 0.0 0.081 13.3 0.0 1.7 1 0 0 1 1 1 0 Transcriptional regulator WAC_Acf1_DNA_bd PF10537.9 EAQ87198.1 - 0.066 13.7 3.7 0.084 13.4 0.6 2.8 2 1 0 2 2 2 0 ATP-utilising chromatin assembly and remodelling N-terminal APG5 PF04106.12 EAQ87198.1 - 0.11 12.1 0.1 0.27 10.8 0.1 1.6 1 0 0 1 1 1 0 Autophagy protein Apg5 AnfG_VnfG PF03139.15 EAQ87198.1 - 0.28 11.3 4.2 3.4 7.8 1.5 3.3 2 1 1 3 3 3 0 Vanadium/alternative nitrogenase delta subunit DUF588 PF04535.12 EAQ87199.1 - 0.039 13.7 1.6 0.06 13.1 1.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF588) 3HCDH_RFF PF18321.1 EAQ87199.1 - 0.11 13.0 0.2 0.35 11.3 0.2 1.9 1 1 0 1 1 1 0 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain Mit_KHE1 PF10173.9 EAQ87200.1 - 5.7e-67 225.5 1.1 8.3e-67 225.0 1.1 1.2 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related GATA PF00320.27 EAQ87202.1 - 1.8e-14 53.0 3.3 3e-14 52.3 3.3 1.4 1 0 0 1 1 1 1 GATA zinc finger ATG16 PF08614.11 EAQ87202.1 - 0.00066 20.0 23.6 0.0011 19.3 18.6 2.3 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) APG6_N PF17675.1 EAQ87202.1 - 0.00085 19.9 14.3 0.00085 19.9 14.3 1.8 2 0 0 2 2 2 1 Apg6 coiled-coil region LMBR1 PF04791.16 EAQ87202.1 - 0.012 14.5 3.2 0.014 14.3 3.2 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein CLZ PF16526.5 EAQ87202.1 - 0.015 15.7 13.8 0.051 13.9 11.1 2.6 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Atg14 PF10186.9 EAQ87202.1 - 0.026 13.6 18.4 0.38 9.8 14.6 2.2 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 TF_Zn_Ribbon PF08271.12 EAQ87202.1 - 0.043 13.3 0.4 0.075 12.6 0.4 1.3 1 0 0 1 1 1 0 TFIIB zinc-binding TcpS PF17456.2 EAQ87202.1 - 0.1 12.7 2.2 0.12 12.4 1.0 1.6 1 1 1 2 2 2 0 Toxin-coregulated pilus protein S Auto_anti-p27 PF06677.12 EAQ87202.1 - 0.16 12.2 0.7 0.26 11.5 0.7 1.3 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) CENP-F_leu_zip PF10473.9 EAQ87202.1 - 0.35 10.9 25.3 0.17 11.9 8.4 2.4 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3584 PF12128.8 EAQ87202.1 - 0.35 8.3 19.3 0.089 10.3 15.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Pox_A_type_inc PF04508.12 EAQ87202.1 - 0.9 9.5 5.9 23 5.0 0.0 3.3 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat T3SSipB PF16535.5 EAQ87202.1 - 1.5 9.3 16.0 1.7 9.1 7.8 2.3 2 0 0 2 2 2 0 Type III cell invasion protein SipB ADIP PF11559.8 EAQ87202.1 - 1.8 8.6 27.4 5.8 7.0 22.1 2.7 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding Macoilin PF09726.9 EAQ87202.1 - 1.9 6.9 10.9 2.5 6.5 10.9 1.1 1 0 0 1 1 1 0 Macoilin family Exonuc_VII_L PF02601.15 EAQ87202.1 - 3.4 7.2 17.2 0.17 11.4 10.1 1.9 1 1 1 2 2 2 0 Exonuclease VII, large subunit Phage_GPO PF05929.11 EAQ87202.1 - 3.8 7.0 11.6 0.54 9.8 7.3 1.7 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF4226 PF10774.9 EAQ87202.1 - 5.3 7.4 13.4 0.44 10.8 5.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4226) Peptidase_C58 PF03543.14 EAQ87202.1 - 5.5 6.7 9.6 10 5.8 5.3 2.2 2 0 0 2 2 2 0 Yersinia/Haemophilus virulence surface antigen Fmp27_WPPW PF10359.9 EAQ87202.1 - 8.9 5.0 16.5 0.94 8.3 12.3 1.4 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain eIF-5_eIF-2B PF01873.17 EAQ87202.1 - 8.9 6.2 6.6 0.65 9.9 0.9 2.1 3 0 0 3 3 3 0 Domain found in IF2B/IF5 KH_8 PF17903.1 EAQ87203.1 - 8.8e-30 102.6 0.0 1.9e-29 101.6 0.0 1.6 1 0 0 1 1 1 1 Krr1 KH1 domain Ribosomal_60s PF00428.19 EAQ87203.1 - 0.4 11.3 7.5 0.82 10.3 7.5 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein Ras PF00071.22 EAQ87206.1 - 1e-43 148.8 0.2 1.2e-43 148.5 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAQ87206.1 - 7.1e-11 42.4 0.0 1e-10 41.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 EAQ87206.1 - 2.8e-05 23.7 0.0 4.6e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Arf PF00025.21 EAQ87206.1 - 0.00021 20.8 0.0 0.00026 20.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family FeoB_N PF02421.18 EAQ87206.1 - 0.017 14.6 0.1 0.023 14.2 0.1 1.3 1 1 0 1 1 1 0 Ferrous iron transport protein B MoCF_biosynth PF00994.24 EAQ87208.1 - 5e-19 68.4 0.0 1.1e-18 67.3 0.0 1.5 1 0 0 1 1 1 1 Probable molybdopterin binding domain Cofilin_ADF PF00241.20 EAQ87209.1 - 5.3e-16 58.5 0.0 6e-16 58.3 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein ParA PF10609.9 EAQ87210.1 - 3.8e-96 321.3 0.0 4.4e-96 321.1 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 EAQ87210.1 - 1.3e-09 38.2 0.0 5.7e-09 36.1 0.0 2.0 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.15 EAQ87210.1 - 5.5e-06 25.8 1.1 7.9e-05 22.0 0.3 2.2 2 1 0 2 2 2 1 Anion-transporting ATPase AAA_31 PF13614.6 EAQ87210.1 - 5.8e-06 26.3 0.3 7.1e-05 22.8 0.3 2.1 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EAQ87210.1 - 0.00033 20.4 0.0 0.00044 20.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_26 PF13500.6 EAQ87210.1 - 0.00034 20.5 0.1 0.072 12.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain MipZ PF09140.11 EAQ87210.1 - 0.00047 19.5 0.0 0.0011 18.3 0.0 1.6 1 1 0 1 1 1 1 ATPase MipZ RsgA_GTPase PF03193.16 EAQ87210.1 - 0.00096 19.1 0.0 0.0017 18.2 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_25 PF13481.6 EAQ87210.1 - 0.0015 18.1 0.2 0.0029 17.2 0.2 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EAQ87210.1 - 0.0024 18.3 0.1 0.0036 17.7 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain Fer4_NifH PF00142.18 EAQ87210.1 - 0.0043 16.5 0.0 0.13 11.7 0.0 2.2 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family CBP_BcsQ PF06564.12 EAQ87210.1 - 0.0058 16.1 0.1 0.059 12.8 0.1 2.0 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ NB-ARC PF00931.22 EAQ87210.1 - 0.0098 15.1 0.0 0.015 14.5 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain TsaE PF02367.17 EAQ87210.1 - 0.012 15.6 0.1 0.022 14.8 0.1 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SRP54 PF00448.22 EAQ87210.1 - 0.02 14.5 0.1 0.038 13.6 0.1 1.5 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain NACHT PF05729.12 EAQ87210.1 - 0.022 14.7 0.2 0.036 14.0 0.2 1.3 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.22 EAQ87210.1 - 0.024 15.0 0.0 0.045 14.1 0.0 1.4 1 0 0 1 1 1 0 RNA helicase MMR_HSR1 PF01926.23 EAQ87210.1 - 0.032 14.3 0.1 3.8 7.6 0.0 2.2 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_5 PF07728.14 EAQ87210.1 - 0.042 13.8 0.1 0.071 13.1 0.1 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EAQ87210.1 - 0.075 13.3 0.1 0.13 12.5 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 EAQ87210.1 - 0.097 12.7 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain CLP1_P PF16575.5 EAQ87210.1 - 0.12 12.2 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Rad17 PF03215.15 EAQ87210.1 - 0.13 12.1 0.0 0.25 11.3 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_18 PF13238.6 EAQ87210.1 - 0.14 12.7 0.0 0.2 12.2 0.0 1.5 1 1 0 1 1 1 0 AAA domain T2SSE PF00437.20 EAQ87210.1 - 0.16 11.0 0.0 0.24 10.4 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein NTPase_1 PF03266.15 EAQ87210.1 - 0.21 11.5 0.1 0.36 10.7 0.1 1.3 1 0 0 1 1 1 0 NTPase KTI12 PF08433.10 EAQ87210.1 - 0.26 10.7 0.0 0.36 10.2 0.0 1.1 1 0 0 1 1 1 0 Chromatin associated protein KTI12 DAP3 PF10236.9 EAQ87210.1 - 0.32 10.1 0.1 0.47 9.6 0.1 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 ECM11 PF15463.6 EAQ87211.1 - 4.3e-45 153.6 1.1 4.3e-45 153.6 1.1 3.9 3 1 1 4 4 4 1 Extracellular mutant protein 11 PNISR PF15996.5 EAQ87211.1 - 0.32 11.2 20.5 1.4 9.1 10.7 2.8 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR DUF3915 PF13054.6 EAQ87211.1 - 0.45 10.5 12.9 0.038 14.0 6.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) AAA_16 PF13191.6 EAQ87212.1 - 0.00035 21.0 0.0 0.0011 19.4 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 EAQ87212.1 - 0.00051 20.6 0.1 0.0011 19.5 0.0 1.6 2 0 0 2 2 1 1 AAA domain NACHT PF05729.12 EAQ87212.1 - 0.006 16.5 0.4 0.011 15.7 0.1 1.5 2 0 0 2 2 1 1 NACHT domain MeaB PF03308.16 EAQ87212.1 - 0.008 15.2 0.1 0.013 14.5 0.1 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB NB-ARC PF00931.22 EAQ87212.1 - 0.0081 15.4 0.2 0.017 14.3 0.0 1.5 2 0 0 2 2 2 1 NB-ARC domain AAA PF00004.29 EAQ87212.1 - 0.011 16.2 0.1 0.017 15.5 0.1 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SRP54 PF00448.22 EAQ87212.1 - 0.02 14.5 0.0 0.028 14.0 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_22 PF13401.6 EAQ87212.1 - 0.02 15.1 0.0 0.032 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 EAQ87212.1 - 0.02 14.1 0.0 0.021 14.1 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain TsaE PF02367.17 EAQ87212.1 - 0.021 14.8 0.0 0.038 14.0 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 EAQ87212.1 - 0.022 15.3 0.0 0.047 14.2 0.0 1.5 2 0 0 2 2 2 0 ABC transporter NTPase_1 PF03266.15 EAQ87212.1 - 0.032 14.2 0.1 0.051 13.5 0.1 1.2 1 0 0 1 1 1 0 NTPase Thymidylate_kin PF02223.17 EAQ87212.1 - 0.042 13.5 0.0 0.063 12.9 0.0 1.3 1 0 0 1 1 1 0 Thymidylate kinase LpxK PF02606.14 EAQ87212.1 - 0.06 12.4 0.0 0.088 11.9 0.0 1.2 1 0 0 1 1 1 0 Tetraacyldisaccharide-1-P 4'-kinase AAA_28 PF13521.6 EAQ87212.1 - 0.063 13.5 0.5 0.15 12.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 EAQ87212.1 - 0.071 13.1 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 EAQ87212.1 - 0.092 12.8 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EAQ87212.1 - 0.093 12.4 0.1 0.2 11.4 0.0 1.5 2 0 0 2 2 1 0 AAA domain AAA_33 PF13671.6 EAQ87212.1 - 0.094 12.9 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EAQ87212.1 - 0.16 11.2 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin cobW PF02492.19 EAQ87212.1 - 0.18 11.4 0.0 0.26 10.9 0.0 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.17 EAQ87212.1 - 0.22 11.3 0.0 0.33 10.7 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.22 EAQ87212.1 - 0.23 11.9 0.0 0.43 11.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase adh_short PF00106.25 EAQ87213.1 - 8.2e-85 283.2 13.0 3.4e-44 150.6 1.2 2.8 3 0 0 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 EAQ87213.1 - 3.1e-65 220.0 8.7 3.6e-34 118.3 1.0 2.6 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase MaoC_dehydratas PF01575.19 EAQ87213.1 - 3.6e-33 113.7 0.0 7e-33 112.8 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain KR PF08659.10 EAQ87213.1 - 1.5e-29 103.2 6.8 4.7e-15 56.0 0.3 2.9 3 0 0 3 3 3 2 KR domain MaoC_dehydrat_N PF13452.6 EAQ87213.1 - 0.00022 21.4 0.0 0.52 10.4 0.0 2.8 3 0 0 3 3 3 2 N-terminal half of MaoC dehydratase THF_DHG_CYH_C PF02882.19 EAQ87213.1 - 0.00087 18.6 0.9 0.011 15.1 0.3 2.4 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.21 EAQ87213.1 - 0.0052 16.3 4.3 0.05 13.1 0.1 2.8 3 0 0 3 3 3 1 NAD dependent epimerase/dehydratase family PglL_A PF15864.5 EAQ87213.1 - 2.4 8.0 8.0 5.4 6.8 1.0 2.4 2 0 0 2 2 2 0 Protein glycosylation ligase FAM25 PF15825.5 EAQ87213.1 - 2.4 8.6 8.1 13 6.2 0.9 2.9 2 0 0 2 2 2 0 FAM25 family 3HCDH_N PF02737.18 EAQ87213.1 - 2.7 7.8 6.5 3.8 7.4 0.9 2.9 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ysc84 PF04366.12 EAQ87214.1 - 3.3e-31 107.7 0.0 6.7e-31 106.7 0.0 1.5 1 0 0 1 1 1 1 Las17-binding protein actin regulator PAC2 PF09754.9 EAQ87214.1 - 0.093 12.7 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 PAC2 family TrkA_TMD PF18613.1 EAQ87214.1 - 0.18 11.3 0.8 0.37 10.3 0.8 1.4 1 0 0 1 1 1 0 Tyrosine kinase receptor A trans-membrane domain PBP1_TM PF14812.6 EAQ87214.1 - 7 7.1 6.1 1.9 8.9 1.2 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4611 PF15387.6 EAQ87214.1 - 8.6 6.7 13.5 1.2 9.4 4.7 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) NOA36 PF06524.12 EAQ87214.1 - 8.9 5.5 6.4 11 5.3 2.4 2.2 2 0 0 2 2 2 0 NOA36 protein F-box_4 PF15966.5 EAQ87216.1 - 0.055 13.4 0.0 0.15 11.9 0.0 1.8 2 0 0 2 2 2 0 F-box IBR PF01485.21 EAQ87217.1 - 2.1e-05 24.6 7.6 2.1e-05 24.6 7.6 4.9 4 1 1 5 5 5 2 IBR domain, a half RING-finger domain DUF1660 PF07874.11 EAQ87217.1 - 7.8 7.1 12.2 24 5.5 2.4 3.9 3 0 0 3 3 3 0 Prophage protein (DUF1660) Actin PF00022.19 EAQ87218.1 - 4.2e-18 65.1 0.0 3e-15 55.8 0.0 2.4 2 0 0 2 2 2 2 Actin FtsA PF14450.6 EAQ87218.1 - 0.062 13.7 0.1 0.18 12.3 0.1 2.0 1 1 0 1 1 1 0 Cell division protein FtsA Ribonuc_L-PSP PF01042.21 EAQ87219.1 - 6.8e-27 93.9 0.0 1e-26 93.3 0.0 1.3 1 0 0 1 1 1 1 Endoribonuclease L-PSP Kelch_5 PF13854.6 EAQ87220.1 - 1.9e-13 50.1 2.3 3.5e-11 42.8 0.6 3.3 3 0 0 3 3 3 2 Kelch motif Kelch_1 PF01344.25 EAQ87220.1 - 4.7e-06 26.1 0.4 0.033 13.8 0.4 3.0 2 0 0 2 2 2 2 Kelch motif Kelch_3 PF13415.6 EAQ87220.1 - 7.1e-06 26.2 3.1 4.6e-05 23.6 0.3 3.7 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_6 PF13964.6 EAQ87220.1 - 6.2e-05 23.1 1.8 0.011 16.0 0.2 3.8 3 1 0 3 3 3 1 Kelch motif Kelch_4 PF13418.6 EAQ87220.1 - 0.00037 20.4 4.8 0.63 10.1 0.1 3.9 4 0 0 4 4 4 2 Galactose oxidase, central domain DUF4381 PF14316.6 EAQ87220.1 - 0.12 12.6 0.2 0.23 11.7 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Lactamase_B PF00753.27 EAQ87221.1 - 3.3e-12 46.8 0.3 6.2e-07 29.6 0.2 2.4 1 1 1 2 2 2 2 Metallo-beta-lactamase superfamily TrmE_N PF10396.9 EAQ87221.1 - 0.17 12.2 0.0 0.34 11.2 0.0 1.5 1 0 0 1 1 1 0 GTP-binding protein TrmE N-terminus Hexokinase_2 PF03727.16 EAQ87222.1 - 1.4e-46 158.9 0.0 2.3e-46 158.2 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 EAQ87222.1 - 2.5e-32 112.4 0.0 4.9e-26 91.9 0.0 2.3 1 1 1 2 2 2 2 Hexokinase MFS_1 PF07690.16 EAQ87222.1 - 1.6e-17 63.5 49.9 2.5e-14 53.0 16.0 3.0 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EAQ87222.1 - 0.0034 15.9 8.1 0.053 11.9 3.5 2.4 1 1 1 2 2 2 2 Fungal trichothecene efflux pump (TRI12) DcpS PF05652.12 EAQ87223.1 - 1.8e-37 128.3 0.0 2.9e-37 127.7 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal DcpS_C PF11969.8 EAQ87223.1 - 3.8e-32 111.1 0.0 7e-32 110.3 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DUF2016 PF09436.10 EAQ87223.1 - 0.046 13.5 0.1 1.1 9.1 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF2016) SPX PF03105.19 EAQ87224.1 - 0.021 14.8 3.1 0.034 14.1 3.1 1.3 1 0 0 1 1 1 0 SPX domain RFamide_26RFa PF11109.8 EAQ87224.1 - 0.54 10.8 4.6 1.8 9.1 3.1 2.2 2 0 0 2 2 2 0 Orexigenic neuropeptide Qrfp/P518 KAR9 PF08580.10 EAQ87224.1 - 0.76 8.2 5.9 1.1 7.7 5.9 1.2 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Ndc1_Nup PF09531.10 EAQ87224.1 - 3.7 6.1 5.9 5 5.7 5.9 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TFCD_C PF12612.8 EAQ87225.1 - 1.4e-26 93.5 0.3 7.5e-26 91.1 0.3 2.4 1 1 0 1 1 1 1 Tubulin folding cofactor D C terminal HEAT PF02985.22 EAQ87225.1 - 0.0018 18.4 0.6 0.047 14.0 0.0 3.9 2 1 0 2 2 2 1 HEAT repeat Vac14_Fab1_bd PF12755.7 EAQ87225.1 - 0.11 13.1 0.3 2.4 8.8 0.0 3.3 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region Glyco_hydro_76 PF03663.14 EAQ87226.1 - 4e-49 168.1 9.1 5e-49 167.8 9.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 EAQ87226.1 - 9.3e-06 24.9 2.1 0.0014 17.8 0.0 2.9 1 1 0 2 2 2 2 Glycosyl Hydrolase Family 88 His_Phos_2 PF00328.22 EAQ87230.1 - 2.7e-109 366.0 0.1 3.9e-109 365.5 0.1 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 EAQ87230.1 - 1.1e-14 54.3 0.0 2.5e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 EAQ87230.1 - 1.5e-06 28.0 0.0 2.8e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Utp21 PF04192.12 EAQ87231.1 - 5e-43 147.3 0.2 3e-38 131.6 0.0 2.2 1 1 1 2 2 2 2 Utp21 specific WD40 associated putative domain WD40 PF00400.32 EAQ87231.1 - 1.8e-14 53.9 20.2 6.1e-06 26.9 0.9 8.0 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAQ87231.1 - 2.1e-10 40.8 0.0 0.00029 21.1 0.0 4.8 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EAQ87231.1 - 6.9e-06 25.0 0.4 2.8 6.5 0.1 4.2 3 1 1 4 4 4 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 EAQ87231.1 - 0.018 13.8 0.1 1.6 7.4 0.0 2.3 1 1 1 2 2 2 0 Nup133 N terminal like Cytochrom_D1 PF02239.16 EAQ87231.1 - 0.026 13.1 0.0 0.042 12.4 0.0 1.2 1 0 0 1 1 1 0 Cytochrome D1 heme domain AA_permease PF00324.21 EAQ87232.1 - 7.6e-114 380.9 36.4 8.7e-114 380.7 36.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EAQ87232.1 - 3.4e-20 72.3 39.9 4.5e-20 71.9 39.9 1.0 1 0 0 1 1 1 1 Amino acid permease S_4TM PF18159.1 EAQ87232.1 - 0.5 9.6 0.0 0.5 9.6 0.0 2.9 4 0 0 4 4 4 0 SMODS-associating 4TM effector domain Orthoreo_P10 PF07204.11 EAQ87232.1 - 0.84 9.6 5.7 0.36 10.8 2.4 2.0 1 1 1 2 2 2 0 Orthoreovirus membrane fusion protein p10 MitMem_reg PF13012.6 EAQ87235.1 - 4.6e-11 43.1 0.7 1.1e-10 42.0 0.7 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 EAQ87235.1 - 2e-09 37.5 0.2 7e-09 35.7 0.0 2.0 3 0 0 3 3 3 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Nore1-SARAH PF16517.5 EAQ87235.1 - 0.1 12.6 0.1 0.23 11.4 0.1 1.6 1 0 0 1 1 1 0 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain MAS20 PF02064.15 EAQ87235.1 - 0.25 11.5 2.1 11 6.2 0.0 2.5 2 0 0 2 2 2 0 MAS20 protein import receptor ADH_N PF08240.12 EAQ87236.1 - 2.4e-25 88.5 1.8 4.3e-25 87.7 1.8 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EAQ87236.1 - 5e-12 45.9 0.0 1.1e-10 41.5 0.0 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EAQ87236.1 - 0.0014 19.7 0.0 0.0028 18.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EAQ87236.1 - 0.13 11.7 0.1 0.52 9.7 0.1 1.8 1 1 0 1 1 1 0 Glucose dehydrogenase C-terminus Vps5 PF09325.10 EAQ87237.1 - 7.2e-13 48.6 1.2 1.4e-12 47.7 1.2 1.3 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 EAQ87237.1 - 5.7e-10 39.2 0.0 1e-09 38.4 0.0 1.4 1 0 0 1 1 1 1 PX domain TPR_12 PF13424.6 EAQ87237.1 - 0.021 15.1 1.5 0.39 11.0 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Seryl_tRNA_N PF02403.22 EAQ87237.1 - 0.44 10.8 3.9 1.1 9.6 3.9 1.6 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain TFIIA PF03153.13 EAQ87237.1 - 0.49 10.3 16.0 0.1 12.6 11.0 1.9 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit GTP_EFTU PF00009.27 EAQ87238.1 - 1.2e-45 155.4 0.0 4e-45 153.8 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 EAQ87238.1 - 6.5e-24 83.8 0.0 1.5e-23 82.6 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 EAQ87238.1 - 6.6e-11 42.1 0.0 0.00036 20.5 0.0 2.6 2 0 0 2 2 2 2 Elongation factor G C-terminus RF3_C PF16658.5 EAQ87238.1 - 0.00052 19.9 0.0 0.0011 18.8 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain Lzipper-MIP1 PF14389.6 EAQ87239.1 - 0.002 18.4 3.6 0.0031 17.8 3.6 1.3 1 0 0 1 1 1 1 Leucine-zipper of ternary complex factor MIP1 BLOC1_2 PF10046.9 EAQ87239.1 - 0.023 15.0 3.9 0.096 13.0 3.9 1.9 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 BRI3BP PF14965.6 EAQ87239.1 - 0.04 13.4 0.1 0.065 12.8 0.1 1.4 1 0 0 1 1 1 0 Negative regulator of p53/TP53 ZapB PF06005.12 EAQ87239.1 - 0.054 13.9 3.1 4.7 7.7 0.0 2.2 2 0 0 2 2 2 0 Cell division protein ZapB DUF4201 PF13870.6 EAQ87239.1 - 0.086 12.6 4.1 0.76 9.5 4.1 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) DivIC PF04977.15 EAQ87239.1 - 0.11 12.3 7.6 0.4 10.5 0.4 2.7 1 1 2 3 3 3 0 Septum formation initiator Ax_dynein_light PF10211.9 EAQ87239.1 - 0.19 11.7 7.8 0.44 10.5 0.5 2.1 1 1 1 2 2 2 0 Axonemal dynein light chain Spc7 PF08317.11 EAQ87239.1 - 0.26 10.1 6.8 0.52 9.1 6.7 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein bZIP_1 PF00170.21 EAQ87239.1 - 1 9.5 5.2 9.1 6.5 0.2 2.2 2 0 0 2 2 2 0 bZIP transcription factor Spc24 PF08286.11 EAQ87239.1 - 2.8 8.2 7.3 0.71 10.1 1.0 2.2 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 SMC_Nse1 PF07574.13 EAQ87241.1 - 1.5e-47 162.0 0.0 1.7e-47 161.9 0.0 1.0 1 0 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex Vps4_C PF09336.10 EAQ87241.1 - 0.073 13.1 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain Parvo_coat_N PF08398.10 EAQ87242.1 - 0.34 11.1 2.3 0.5 10.6 0.6 2.2 2 1 0 2 2 2 0 Parvovirus coat protein VP1 SPRY PF00622.28 EAQ87243.1 - 0.00078 19.5 0.1 0.017 15.2 0.0 2.9 3 0 0 3 3 3 1 SPRY domain Myb_Cef PF11831.8 EAQ87244.1 - 4e-49 167.3 11.2 4e-49 167.3 11.2 2.8 3 0 0 3 3 3 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.31 EAQ87244.1 - 1.4e-22 79.6 5.0 8.5e-11 41.9 0.9 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAQ87244.1 - 1.1e-21 76.8 7.4 6.4e-15 55.1 2.8 2.8 1 1 1 2 2 2 2 Myb-like DNA-binding domain Rap1_C PF11626.8 EAQ87244.1 - 0.055 13.6 6.5 0.11 12.6 0.0 3.7 4 0 0 4 4 4 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Pyr_redox_2 PF07992.14 EAQ87249.1 - 2.3e-11 43.5 0.5 0.0013 18.0 0.0 3.2 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EAQ87249.1 - 0.00026 20.3 0.1 0.00086 18.5 0.0 1.7 1 1 1 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 EAQ87249.1 - 0.00062 19.8 2.9 0.03 14.3 0.0 2.3 1 1 1 2 2 2 2 FAD-NAD(P)-binding GIDA PF01134.22 EAQ87249.1 - 0.021 13.9 3.1 0.34 9.9 0.1 2.1 1 1 1 2 2 2 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 EAQ87249.1 - 0.08 12.2 3.3 2.6 7.2 0.0 2.4 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EAQ87249.1 - 1.1 8.2 2.9 21 4.0 1.3 2.4 2 1 1 3 3 3 0 Lycopene cyclase protein FAD_binding_2 PF00890.24 EAQ87249.1 - 2 7.4 6.1 7.1 5.6 2.7 2.7 3 0 0 3 3 3 0 FAD binding domain DUF4360 PF14273.6 EAQ87250.1 - 3e-31 108.7 0.0 3.6e-31 108.4 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) CENP-Q PF13094.6 EAQ87251.1 - 0.015 15.5 3.3 1.6 8.9 0.1 3.0 2 1 1 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit YvrJ PF12841.7 EAQ87251.1 - 1.1 8.8 2.4 2 8.0 0.0 2.7 4 0 0 4 4 4 0 YvrJ protein family peroxidase PF00141.23 EAQ87253.1 - 1.4e-18 67.5 0.0 3.1e-18 66.3 0.0 1.5 2 0 0 2 2 2 1 Peroxidase DUF4195 PF13836.6 EAQ87255.1 - 0.057 13.5 0.1 0.064 13.4 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4195) DOG1 PF14144.6 EAQ87255.1 - 0.069 13.4 0.0 0.091 13.0 0.0 1.3 1 0 0 1 1 1 0 Seed dormancy control Inositol_P PF00459.25 EAQ87256.1 - 4.8e-64 216.5 0.1 5.4e-64 216.3 0.1 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family MFS_1 PF07690.16 EAQ87257.1 - 1.7e-18 66.7 32.9 8.7e-11 41.3 8.7 2.8 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EAQ87257.1 - 1.6e-07 30.6 3.8 1.6e-07 30.6 3.8 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_5 PF05631.14 EAQ87257.1 - 0.0026 16.8 0.2 0.0045 16.0 0.2 1.3 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM Antimicrobial24 PF16049.5 EAQ87257.1 - 0.12 12.3 1.1 0.27 11.2 1.1 1.6 1 0 0 1 1 1 0 Frog antimicrobial peptide MFS_1_like PF12832.7 EAQ87257.1 - 2.3 7.0 8.7 0.52 9.1 1.5 2.5 2 0 0 2 2 2 0 MFS_1 like family Dioxygenase_C PF00775.21 EAQ87259.1 - 4.7e-08 32.7 0.1 8.1e-08 31.9 0.1 1.3 1 0 0 1 1 1 1 Dioxygenase His_Phos_2 PF00328.22 EAQ87261.1 - 3.8e-71 240.4 0.0 4.4e-71 240.2 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) SSP160 PF06933.11 EAQ87262.1 - 1.3 7.2 12.9 2.1 6.4 12.9 1.3 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Sec62 PF03839.16 EAQ87263.1 - 5.5e-72 241.8 0.7 5.5e-72 241.8 0.7 2.0 2 0 0 2 2 2 1 Translocation protein Sec62 Zip PF02535.22 EAQ87263.1 - 0.013 14.7 1.5 0.045 13.0 1.1 1.9 2 0 0 2 2 2 0 ZIP Zinc transporter SelP_N PF04592.14 EAQ87263.1 - 0.044 13.2 16.4 0.092 12.1 16.4 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF4834 PF16118.5 EAQ87263.1 - 0.1 13.6 6.5 44 5.1 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4834) CCDC53 PF10152.9 EAQ87263.1 - 0.14 12.6 4.2 12 6.3 7.0 2.3 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Neur_chan_memb PF02932.16 EAQ87263.1 - 0.63 10.1 3.3 7.2 6.6 4.9 1.9 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region NST1 PF13945.6 EAQ87263.1 - 2.6 8.1 9.8 8.4 6.4 0.2 2.3 2 0 0 2 2 2 0 Salt tolerance down-regulator EPL1 PF10513.9 EAQ87263.1 - 4.8 7.5 8.1 0.57 10.6 4.0 1.6 2 0 0 2 2 2 0 Enhancer of polycomb-like CAF20 PF17052.5 EAQ87263.1 - 5 7.3 7.9 9.1 6.4 7.9 1.4 1 0 0 1 1 1 0 Cap associated factor MMR1 PF08505.10 EAQ87263.1 - 8.3 6.6 10.4 0.51 10.6 5.3 1.6 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein PLDc_2 PF13091.6 EAQ87264.1 - 1.7e-17 63.5 0.1 3e-06 27.2 0.0 4.0 3 1 0 3 3 3 3 PLD-like domain PLDc PF00614.22 EAQ87264.1 - 2e-10 40.4 0.1 0.0007 19.7 0.0 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif Regulator_TrmB PF11495.8 EAQ87264.1 - 0.14 11.3 0.0 0.31 10.2 0.0 1.5 1 0 0 1 1 1 0 Archaeal transcriptional regulator TrmB Thioredoxin PF00085.20 EAQ87265.1 - 2.2e-31 107.9 0.0 1.7e-24 85.8 0.0 3.5 3 1 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 EAQ87265.1 - 1e-08 35.3 0.0 0.00034 20.6 0.0 3.4 1 1 2 3 3 3 2 Thioredoxin-like domain Thioredoxin_2 PF13098.6 EAQ87265.1 - 0.00011 22.6 0.0 0.0088 16.5 0.0 2.8 3 0 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EAQ87265.1 - 0.0013 19.0 0.1 0.2 12.0 0.0 3.9 4 1 0 4 4 4 1 Thioredoxin-like HyaE PF07449.11 EAQ87265.1 - 0.0061 16.5 0.0 7.9 6.5 0.0 3.9 4 0 0 4 4 4 1 Hydrogenase-1 expression protein HyaE UBN_AB PF14075.6 EAQ87265.1 - 0.046 13.4 0.4 0.077 12.7 0.4 1.2 1 0 0 1 1 1 0 Ubinuclein conserved middle domain Thioredoxin_5 PF13743.6 EAQ87265.1 - 0.059 13.1 0.0 6.2 6.5 0.1 2.5 1 1 1 2 2 2 0 Thioredoxin Tyr-DNA_phospho PF06087.12 EAQ87266.1 - 3.1e-95 319.6 0.0 3.5e-95 319.4 0.0 1.0 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase ACBP PF00887.19 EAQ87267.1 - 1.7e-17 63.4 2.2 2.1e-17 63.1 2.2 1.1 1 0 0 1 1 1 1 Acyl CoA binding protein Pyr_redox_2 PF07992.14 EAQ87268.1 - 3.3e-33 115.2 0.4 4e-33 114.9 0.4 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EAQ87268.1 - 1.6e-06 28.6 2.4 0.00077 20.0 0.7 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EAQ87268.1 - 0.0034 16.6 0.0 0.055 12.6 0.0 2.2 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) ETF_alpha PF00766.19 EAQ87268.1 - 0.066 13.2 3.1 0.24 11.4 0.2 2.9 3 0 0 3 3 3 0 Electron transfer flavoprotein FAD-binding domain NAD_binding_8 PF13450.6 EAQ87268.1 - 0.076 13.3 0.5 2 8.7 0.0 2.4 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EAQ87268.1 - 0.18 11.8 0.6 9.3 6.2 0.0 3.3 3 1 1 4 4 4 0 FAD-NAD(P)-binding DAO PF01266.24 EAQ87268.1 - 0.73 9.4 12.3 1.1 8.8 0.1 3.6 2 2 2 4 4 4 0 FAD dependent oxidoreductase End3 PF12761.7 EAQ87269.1 - 8.5e-78 261.1 1.5 1.1e-77 260.7 1.5 1.2 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_4 PF12763.7 EAQ87269.1 - 9.4e-50 166.9 0.0 2.9e-48 162.1 0.0 2.2 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 EAQ87269.1 - 3.9e-07 29.1 0.2 8.5e-07 28.1 0.2 1.6 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 EAQ87269.1 - 1.3e-05 25.6 0.0 4.3e-05 23.9 0.0 2.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 EAQ87269.1 - 0.00084 19.1 0.2 0.0027 17.5 0.2 1.9 1 0 0 1 1 1 1 EF-hand domain EF-hand_8 PF13833.6 EAQ87269.1 - 0.0021 17.8 0.1 0.0039 17.0 0.1 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 EAQ87269.1 - 0.022 14.2 0.1 0.062 12.8 0.1 1.7 1 0 0 1 1 1 0 EF hand MDMPI_N PF11716.8 EAQ87269.1 - 0.024 15.3 0.0 0.024 15.3 0.0 2.4 2 1 0 2 2 2 0 Mycothiol maleylpyruvate isomerase N-terminal domain CCDC-167 PF15188.6 EAQ87269.1 - 1.1 9.7 6.4 2.7e+02 2.0 6.4 2.7 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 Wtap PF17098.5 EAQ87269.1 - 8.8 6.2 8.0 45 3.9 6.3 2.6 2 1 0 2 2 2 0 WTAP/Mum2p family Mga PF05043.13 EAQ87271.1 - 0.056 14.0 0.2 0.12 13.0 0.2 1.5 1 0 0 1 1 1 0 Mga helix-turn-helix domain Ax_dynein_light PF10211.9 EAQ87271.1 - 0.23 11.4 6.5 3.2 7.6 3.1 2.4 2 0 0 2 2 2 0 Axonemal dynein light chain DivIVA PF05103.13 EAQ87271.1 - 0.38 10.9 8.0 0.47 10.5 2.5 2.3 2 0 0 2 2 2 0 DivIVA protein GrpE PF01025.19 EAQ87271.1 - 7.6 6.2 7.9 1.9 8.1 3.3 2.1 2 0 0 2 2 2 0 GrpE VASt PF16016.5 EAQ87272.1 - 1.4e-39 135.9 0.0 2.3e-39 135.2 0.0 1.3 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 EAQ87272.1 - 1.5e-23 82.9 0.0 2.4e-23 82.2 0.0 1.3 1 0 0 1 1 1 1 GRAM domain OPT PF03169.15 EAQ87273.1 - 2.6e-208 693.6 35.6 3.1e-208 693.3 35.6 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein 5-FTHF_cyc-lig PF01812.20 EAQ87274.1 - 7.4e-25 87.9 0.0 1e-24 87.4 0.0 1.2 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family Xpo1 PF08389.12 EAQ87275.1 - 1.7e-27 96.3 0.1 7e-27 94.3 0.1 2.2 1 0 0 1 1 1 1 Exportin 1-like protein Death PF00531.22 EAQ87275.1 - 0.061 13.5 0.0 0.33 11.2 0.0 2.3 1 0 0 1 1 1 0 Death domain HEAT_EZ PF13513.6 EAQ87275.1 - 0.094 13.2 5.4 6.5 7.4 0.0 5.8 6 1 1 7 7 7 0 HEAT-like repeat Importin_rep_3 PF18806.1 EAQ87275.1 - 0.13 12.3 0.1 1.7 8.7 0.0 2.8 3 0 0 3 3 3 0 Importin 13 repeat Adaptin_N PF01602.20 EAQ87275.1 - 0.13 10.8 0.6 3.3 6.2 0.2 2.2 2 0 0 2 2 2 0 Adaptin N terminal region SLATT_fungal PF18142.1 EAQ87276.1 - 2e-25 89.1 0.1 2.6e-25 88.8 0.1 1.1 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain TRM PF02005.16 EAQ87277.1 - 1e-107 360.6 0.0 4.1e-92 309.3 0.0 2.1 1 1 1 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase PDEase_I PF00233.19 EAQ87277.1 - 0.12 12.1 0.1 0.21 11.3 0.1 1.3 1 0 0 1 1 1 0 3'5'-cyclic nucleotide phosphodiesterase DAGK_cat PF00781.24 EAQ87278.1 - 1.1e-08 34.7 0.0 2.4e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain ABC_tran PF00005.27 EAQ87279.1 - 1.7e-30 106.3 1.4 2.3e-18 67.0 0.0 2.7 3 0 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 EAQ87279.1 - 4e-10 40.0 8.3 0.0024 17.7 0.0 3.3 2 1 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EAQ87279.1 - 0.00074 19.0 0.4 1.3 8.4 0.0 3.1 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 EAQ87279.1 - 0.0023 18.0 0.0 0.0077 16.3 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran_Xtn PF12848.7 EAQ87279.1 - 0.0065 16.5 0.6 0.016 15.2 0.6 1.6 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 EAQ87279.1 - 0.034 13.9 0.1 0.071 12.9 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EAQ87279.1 - 0.037 13.9 0.1 0.59 10.0 0.1 2.5 3 0 0 3 3 3 0 RsgA GTPase AAA_23 PF13476.6 EAQ87279.1 - 0.12 12.8 0.0 0.12 12.8 0.0 2.0 3 0 0 3 3 3 0 AAA domain Sugar_tr PF00083.24 EAQ87280.1 - 3.5e-11 42.6 0.2 1.8e-05 23.8 0.2 2.2 1 1 1 2 2 2 2 Sugar (and other) transporter SSP160 PF06933.11 EAQ87282.1 - 0.21 9.8 7.5 0.3 9.2 7.5 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 zf-H2C2_2 PF13465.6 EAQ87288.1 - 2.2e-06 27.8 18.0 0.00013 22.3 5.2 3.6 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 EAQ87288.1 - 6.2e-06 26.4 23.2 0.0016 18.8 5.8 2.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EAQ87288.1 - 0.0015 19.2 13.9 0.29 12.1 3.8 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 EAQ87288.1 - 0.0093 15.9 1.6 3.4 7.8 0.3 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger Spt20 PF12090.8 EAQ87288.1 - 0.043 13.4 8.9 0.03 14.0 7.4 1.5 2 0 0 2 2 2 0 Spt20 family zf-C2H2_jaz PF12171.8 EAQ87288.1 - 0.19 12.1 3.1 0.37 11.1 0.8 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 EAQ87288.1 - 3.3 7.5 12.3 3.5 7.5 0.2 3.5 3 0 0 3 3 3 0 C2H2-type zinc-finger domain Bromodomain PF00439.25 EAQ87291.1 - 4.3e-17 61.9 0.0 7.7e-17 61.1 0.0 1.4 1 0 0 1 1 1 1 Bromodomain TIM21 PF08294.11 EAQ87292.1 - 2e-25 89.4 0.0 2.5e-25 89.0 0.0 1.1 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.10 EAQ87292.1 - 0.048 13.4 0.0 0.071 12.9 0.0 1.2 1 0 0 1 1 1 0 Cytochrome oxidase complex assembly protein 1 DUF4199 PF13858.6 EAQ87292.1 - 0.19 12.1 0.0 0.25 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) ArfGap PF01412.18 EAQ87293.1 - 3.2e-26 91.7 0.2 5.9e-26 90.8 0.2 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf NDT80_PhoG PF05224.12 EAQ87295.1 - 1.7e-32 113.2 0.2 2.5e-24 86.5 0.0 2.3 1 1 1 2 2 2 2 NDT80 / PhoG like DNA-binding family Pterin_bind PF00809.22 EAQ87300.1 - 6.3e-69 232.4 0.0 1.5e-64 218.0 0.0 2.6 2 1 0 2 2 2 2 Pterin binding enzyme HPPK PF01288.20 EAQ87300.1 - 3.1e-36 124.3 0.0 6.1e-36 123.3 0.0 1.5 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) NMO PF03060.15 EAQ87301.1 - 9.4e-55 186.3 0.3 1.3e-54 185.8 0.3 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 EAQ87301.1 - 8.2e-12 44.8 1.1 1.2e-11 44.2 1.1 1.2 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 EAQ87301.1 - 3.1e-08 33.0 1.1 5e-08 32.4 1.1 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 EAQ87301.1 - 0.069 12.3 0.9 0.15 11.2 0.9 1.5 1 0 0 1 1 1 0 Conserved region in glutamate synthase NanE PF04131.14 EAQ87301.1 - 0.12 11.5 0.3 0.44 9.7 0.3 1.8 1 1 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase SUR7 PF06687.12 EAQ87302.1 - 1.3e-07 31.5 0.0 1.5e-07 31.2 0.0 1.1 1 0 0 1 1 1 1 SUR7/PalI family Senescence PF06911.12 EAQ87302.1 - 0.022 15.1 0.4 0.24 11.7 0.2 2.6 2 1 0 2 2 2 0 Senescence-associated protein LEA_4 PF02987.16 EAQ87302.1 - 0.16 12.1 2.2 0.46 10.6 2.2 1.8 1 0 0 1 1 1 0 Late embryogenesis abundant protein DUF2207 PF09972.9 EAQ87302.1 - 0.26 10.0 0.2 0.4 9.4 0.2 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) MscL PF01741.18 EAQ87303.1 - 5.7e-17 62.1 0.1 7.1e-17 61.8 0.1 1.1 1 0 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL Glyco_hydro_76 PF03663.14 EAQ87306.1 - 3e-138 461.3 2.5 3.5e-138 461.1 2.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_127 PF07944.12 EAQ87306.1 - 0.019 13.5 0.6 0.046 12.2 0.0 1.7 2 0 0 2 2 2 0 Beta-L-arabinofuranosidase, GH127 Glyco_hydro_88 PF07470.13 EAQ87306.1 - 0.026 13.6 4.7 2.9 6.9 0.1 3.1 2 1 1 3 3 3 0 Glycosyl Hydrolase Family 88 GlcNAc_2-epim PF07221.11 EAQ87306.1 - 0.067 12.4 3.4 4.9 6.3 0.2 2.6 2 1 1 3 3 3 0 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) Aminotran_1_2 PF00155.21 EAQ87307.1 - 2.3e-58 198.1 0.0 2.8e-58 197.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DUF2436 PF10365.9 EAQ87307.1 - 0.16 11.7 0.0 0.3 10.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2436) Lipase_GDSL PF00657.22 EAQ87308.1 - 4.5e-13 49.6 0.0 6.4e-13 49.1 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 EAQ87308.1 - 1.3e-07 32.2 0.1 2.1e-07 31.5 0.1 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family FAM76 PF16046.5 EAQ87309.1 - 0.98 8.7 13.5 1.4 8.2 13.5 1.1 1 0 0 1 1 1 0 FAM76 protein SRP-alpha_N PF04086.13 EAQ87309.1 - 2.5 7.9 16.0 4.4 7.1 16.0 1.4 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF4551 PF15087.6 EAQ87309.1 - 7.3 5.3 18.7 11 4.7 18.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Miga PF10265.9 EAQ87309.1 - 7.3 5.4 10.8 10 5.0 10.8 1.1 1 0 0 1 1 1 0 Mitoguardin YjbE PF11106.8 EAQ87309.1 - 7.6 6.8 9.0 20 5.5 9.0 1.6 1 0 0 1 1 1 0 Exopolysaccharide production protein YjbE Zip PF02535.22 EAQ87309.1 - 8.8 5.4 7.5 12 5.0 7.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter RabGAP-TBC PF00566.18 EAQ87310.1 - 1.5e-48 165.3 0.4 1.5e-47 162.1 0.0 2.3 2 0 0 2 2 2 1 Rab-GTPase-TBC domain APG6_N PF17675.1 EAQ87310.1 - 0.00058 20.4 20.8 0.16 12.5 6.6 3.4 3 0 0 3 3 3 3 Apg6 coiled-coil region DUF1664 PF07889.12 EAQ87310.1 - 0.0037 17.3 3.6 0.0037 17.3 3.6 2.6 3 0 0 3 3 2 1 Protein of unknown function (DUF1664) YabA PF06156.13 EAQ87310.1 - 0.0049 17.5 5.6 0.023 15.3 0.2 3.4 3 0 0 3 3 3 1 Initiation control protein YabA Tropomyosin_1 PF12718.7 EAQ87310.1 - 0.017 15.3 8.5 0.017 15.3 8.5 2.7 3 0 0 3 3 3 0 Tropomyosin like CENP-F_leu_zip PF10473.9 EAQ87310.1 - 0.074 13.1 22.1 0.018 15.1 8.3 3.5 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Golgin_A5 PF09787.9 EAQ87310.1 - 0.074 12.5 18.8 0.039 13.4 8.5 3.2 3 0 0 3 3 3 0 Golgin subfamily A member 5 DUF4763 PF15960.5 EAQ87310.1 - 0.086 12.1 17.8 6.8 5.9 7.9 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4763) ADIP PF11559.8 EAQ87310.1 - 0.097 12.8 25.3 0.017 15.2 11.1 3.2 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding Laminin_II PF06009.12 EAQ87310.1 - 0.1 12.6 15.6 0.026 14.5 3.3 2.8 3 0 0 3 3 3 0 Laminin Domain II DUF4201 PF13870.6 EAQ87310.1 - 0.11 12.3 21.3 0.052 13.3 9.4 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4201) IFT57 PF10498.9 EAQ87310.1 - 0.13 11.2 12.4 0.041 12.9 4.0 2.6 3 0 0 3 3 2 0 Intra-flagellar transport protein 57 Fez1 PF06818.15 EAQ87310.1 - 0.23 11.9 20.5 6.5 7.2 16.4 2.9 2 1 0 2 2 2 0 Fez1 HR1 PF02185.16 EAQ87310.1 - 0.39 10.9 17.8 1 9.5 1.1 4.0 3 0 0 3 3 3 0 Hr1 repeat LCD1 PF09798.9 EAQ87310.1 - 0.43 9.0 2.7 0.6 8.6 2.7 1.2 1 0 0 1 1 1 0 DNA damage checkpoint protein Jnk-SapK_ap_N PF09744.9 EAQ87310.1 - 0.76 10.0 22.2 0.41 10.9 7.5 3.4 3 0 0 3 3 3 0 JNK_SAPK-associated protein-1 GAS PF13851.6 EAQ87310.1 - 0.79 9.0 20.8 0.11 11.8 7.5 3.5 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding BST2 PF16716.5 EAQ87310.1 - 0.87 10.2 18.0 0.039 14.5 5.6 3.4 3 0 0 3 3 3 0 Bone marrow stromal antigen 2 DUF724 PF05266.14 EAQ87310.1 - 1.2 8.9 17.8 0.046 13.5 5.4 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF724) XkdW PF09636.10 EAQ87310.1 - 1.3 9.2 3.8 2.6 8.2 0.4 2.7 2 0 0 2 2 2 0 XkdW protein DUF1732 PF08340.11 EAQ87310.1 - 2.8 8.0 6.7 0.31 11.0 1.7 2.1 2 0 0 2 2 1 0 Domain of unknown function (DUF1732) Filament PF00038.21 EAQ87310.1 - 2.9 7.4 17.6 0.17 11.4 6.6 2.8 3 0 0 3 3 3 0 Intermediate filament protein Spc7 PF08317.11 EAQ87310.1 - 4 6.2 22.8 0.8 8.5 8.9 3.9 3 1 1 4 4 4 0 Spc7 kinetochore protein Fib_alpha PF08702.10 EAQ87310.1 - 4.2 7.5 6.4 2 8.6 2.6 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family CENP-H PF05837.12 EAQ87310.1 - 4.7 7.7 21.5 24 5.4 0.4 3.7 3 0 0 3 3 3 0 Centromere protein H (CENP-H) TMPIT PF07851.13 EAQ87310.1 - 5.9 6.0 6.0 1.8 7.8 2.1 2.0 2 0 0 2 2 2 0 TMPIT-like protein DHR10 PF18595.1 EAQ87310.1 - 6.3 6.9 32.7 0.1 12.7 7.0 4.3 3 1 1 4 4 4 0 Designed helical repeat protein 10 domain DUF2203 PF09969.9 EAQ87310.1 - 6.5 7.5 9.0 3.9 8.2 2.2 3.4 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2203) PI3K_P85_iSH2 PF16454.5 EAQ87310.1 - 6.7 6.3 14.1 0.69 9.5 5.3 2.9 3 0 0 3 3 3 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Cnn_1N PF07989.11 EAQ87310.1 - 7.1 6.9 23.7 0.27 11.4 0.5 4.5 3 1 1 4 4 4 0 Centrosomin N-terminal motif 1 EMP24_GP25L PF01105.24 EAQ87310.1 - 7.6 6.4 8.1 2.7 7.9 3.1 2.2 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD DUF3450 PF11932.8 EAQ87310.1 - 9.7 5.4 17.8 0.043 13.1 4.4 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3450) Reticulon PF02453.17 EAQ87311.1 - 1.1e-33 116.4 6.5 1.7e-33 115.8 6.5 1.3 1 0 0 1 1 1 1 Reticulon DNA_topoisoIV PF00521.20 EAQ87312.1 - 7.6e-128 427.0 0.3 1.6e-127 426.0 0.2 1.6 2 0 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 EAQ87312.1 - 8.6e-44 148.9 2.1 8.6e-44 148.9 2.1 2.7 3 0 0 3 3 3 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 EAQ87312.1 - 5.5e-25 87.8 1.0 1.1e-24 86.8 1.0 1.5 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 EAQ87312.1 - 1e-12 48.5 0.1 2.9e-12 47.1 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 EAQ87312.1 - 1.1e-06 28.7 0.1 2.5e-05 24.4 0.0 2.8 2 0 0 2 2 2 1 Toprim domain HATPase_c_3 PF13589.6 EAQ87312.1 - 0.00089 19.1 0.4 0.0027 17.6 0.4 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Imm-NTF2 PF15655.6 EAQ87312.1 - 0.039 14.2 1.0 0.21 11.9 1.0 2.3 1 0 0 1 1 1 0 NTF2 fold immunity protein TPR_2 PF07719.17 EAQ87315.1 - 2.5e-07 30.3 5.4 0.025 14.7 0.1 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 EAQ87315.1 - 5.6e-07 29.1 4.4 0.02 14.7 0.2 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 EAQ87315.1 - 0.01 16.3 1.6 0.047 14.2 1.6 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat Dynamin_N PF00350.23 EAQ87316.1 - 7.5e-14 52.1 2.0 3.9e-13 49.8 0.0 3.0 3 1 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.23 EAQ87316.1 - 0.00051 20.1 0.0 0.0066 16.5 0.0 2.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Vezatin PF12632.7 EAQ87316.1 - 0.011 15.1 0.4 0.18 11.1 0.0 2.3 2 0 0 2 2 2 0 Mysoin-binding motif of peroxisomes ABC_tran PF00005.27 EAQ87316.1 - 0.018 15.6 2.0 0.054 14.0 0.0 2.7 3 0 0 3 3 2 0 ABC transporter AAA_22 PF13401.6 EAQ87316.1 - 0.029 14.7 0.1 1.1 9.6 0.0 3.3 3 0 0 3 3 3 0 AAA domain RsgA_GTPase PF03193.16 EAQ87316.1 - 0.055 13.4 0.0 0.64 9.9 0.0 2.6 2 0 0 2 2 2 0 RsgA GTPase Prominin PF05478.11 EAQ87316.1 - 1 7.2 5.8 1.2 7.0 0.0 3.0 4 0 0 4 4 4 0 Prominin FlaC_arch PF05377.11 EAQ87316.1 - 1.2 9.6 15.9 0.75 10.2 0.1 4.3 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) AAA_16 PF13191.6 EAQ87316.1 - 1.8 8.9 13.4 0.11 12.9 0.4 4.8 5 2 0 5 5 5 0 AAA ATPase domain Med30 PF11315.8 EAQ87316.1 - 2.5 8.3 8.5 58 3.9 4.3 3.6 3 0 0 3 3 3 0 Mediator complex subunit 30 NPV_P10 PF05531.12 EAQ87316.1 - 3 8.4 5.8 3.9 8.0 0.0 3.9 5 0 0 5 5 5 0 Nucleopolyhedrovirus P10 protein DUF4140 PF13600.6 EAQ87316.1 - 7.6 7.0 14.4 5.2 7.6 0.1 4.3 4 0 0 4 4 4 0 N-terminal domain of unknown function (DUF4140) cwf21 PF08312.12 EAQ87316.1 - 9.5 6.5 13.3 47 4.2 0.4 3.8 2 1 0 2 2 2 0 cwf21 domain NmrA PF05368.13 EAQ87317.1 - 3.5e-49 167.5 0.3 4.3e-49 167.2 0.3 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EAQ87317.1 - 1.4e-13 51.2 1.4 2.1e-13 50.6 1.4 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EAQ87317.1 - 0.00023 20.7 0.4 0.0025 17.3 0.1 2.2 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 EAQ87317.1 - 0.00076 19.7 1.0 0.0024 18.2 1.0 1.8 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 EAQ87317.1 - 0.076 13.3 0.1 0.17 12.2 0.1 1.7 1 1 0 1 1 1 0 TrkA-N domain 3Beta_HSD PF01073.19 EAQ87317.1 - 0.098 11.6 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Med3 PF11593.8 EAQ87317.1 - 0.28 10.3 2.3 0.34 10.0 2.3 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Glyco_hydro_43 PF04616.14 EAQ87318.1 - 1.4e-48 165.7 8.6 1.8e-48 165.3 8.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 CBM_6 PF03422.15 EAQ87318.1 - 5.5e-30 104.2 0.6 5.5e-30 104.2 0.6 2.2 3 0 0 3 3 3 1 Carbohydrate binding module (family 6) DUF5010_C PF18099.1 EAQ87318.1 - 2.5e-09 37.3 0.0 5.5e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 DUF5010 C-terminal domain Glyco_hydro_32N PF00251.20 EAQ87318.1 - 0.057 13.0 4.1 0.1 12.2 4.1 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 32 N-terminal domain FAD_binding_4 PF01565.23 EAQ87319.1 - 2.1e-21 76.1 2.9 3.1e-21 75.6 2.9 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EAQ87319.1 - 1.8e-12 47.2 0.5 3.2e-12 46.3 0.0 1.7 2 0 0 2 2 2 1 Berberine and berberine like RT_RNaseH PF17917.1 EAQ87320.1 - 1.3e-31 108.9 0.0 3.4e-31 107.6 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 EAQ87320.1 - 2e-29 101.6 0.0 5.1e-29 100.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 EAQ87320.1 - 3.8e-26 92.0 0.0 1.1e-25 90.5 0.0 1.9 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 EAQ87320.1 - 2e-21 75.9 0.1 5.5e-21 74.4 0.1 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 EAQ87320.1 - 5.1e-13 49.3 0.0 5.7e-12 45.9 0.0 2.6 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 EAQ87320.1 - 0.0055 16.9 0.0 0.015 15.5 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger zf-CCHC_5 PF14787.6 EAQ87320.1 - 0.012 15.3 1.5 0.034 13.9 1.5 1.8 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger Retrotrans_gag PF03732.17 EAQ87320.1 - 0.038 14.3 3.4 0.059 13.7 0.3 3.1 2 0 0 2 2 2 0 Retrotransposon gag protein SHE3 PF17078.5 EAQ87320.1 - 1.4 8.6 8.3 2.5 7.7 1.2 2.5 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 HLH PF00010.26 EAQ87321.1 - 1.9e-08 34.1 0.0 4.4e-08 33.0 0.0 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Sulfate_transp PF00916.20 EAQ87322.1 - 4e-114 381.3 16.2 5e-114 381.0 16.2 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 EAQ87322.1 - 9.9e-09 34.9 0.0 2.2e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 EAQ87322.1 - 0.00018 21.9 2.8 0.00018 21.9 2.8 2.8 2 1 0 2 2 2 1 Molybdate transporter of MFS superfamily STAS_2 PF13466.6 EAQ87322.1 - 0.081 13.3 0.1 0.2 12.0 0.1 1.6 1 0 0 1 1 1 0 STAS domain AAA PF00004.29 EAQ87323.1 - 3.3e-11 43.7 0.0 6e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EAQ87323.1 - 4.5e-06 27.0 0.0 1.1e-05 25.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 EAQ87323.1 - 0.0001 22.1 0.0 0.00019 21.2 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 EAQ87323.1 - 0.00046 20.4 0.0 0.0012 19.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EAQ87323.1 - 0.00088 19.3 0.0 0.0023 18.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EAQ87323.1 - 0.0011 19.4 0.1 0.011 16.2 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain Rad17 PF03215.15 EAQ87323.1 - 0.0015 18.5 0.0 0.0039 17.1 0.0 1.6 1 0 0 1 1 1 1 Rad17 P-loop domain NB-ARC PF00931.22 EAQ87323.1 - 0.01 15.1 0.0 0.018 14.2 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_11 PF13086.6 EAQ87323.1 - 0.016 15.0 0.1 0.92 9.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EAQ87323.1 - 0.02 14.6 0.0 0.058 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 EAQ87323.1 - 0.046 13.8 0.0 0.082 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EAQ87323.1 - 0.18 11.7 0.0 0.33 10.8 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase ABC_tran PF00005.27 EAQ87323.1 - 0.19 12.2 0.2 0.59 10.6 0.0 1.8 2 0 0 2 2 2 0 ABC transporter zf-RVT PF13966.6 EAQ87326.1 - 0.059 14.1 0.0 0.32 11.7 0.0 2.3 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase DUF1772 PF08592.11 EAQ87328.1 - 1.8e-19 70.4 2.6 4e-19 69.3 2.6 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) SGP PF17228.2 EAQ87329.1 - 8.2 7.4 11.3 14 6.6 11.3 1.4 1 0 0 1 1 1 0 Sulphur globule protein Amidohydro_1 PF01979.20 EAQ87330.1 - 8e-65 219.4 0.0 1e-64 219.0 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EAQ87330.1 - 6.2e-11 42.4 6.3 7.8e-09 35.5 3.2 2.5 2 1 0 2 2 2 2 Amidohydrolase family tRNA_int_end_N2 PF12928.7 EAQ87330.1 - 0.13 12.4 0.0 0.37 11.0 0.0 1.8 1 0 0 1 1 1 0 tRNA-splicing endonuclease subunit sen54 N-term ACPS PF01648.20 EAQ87331.1 - 7.1e-19 68.0 0.0 1e-18 67.5 0.0 1.2 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Fas_alpha_ACP PF18325.1 EAQ87332.1 - 5.9e-76 254.3 0.0 1.1e-75 253.4 0.0 1.5 1 0 0 1 1 1 1 Fatty acid synthase subunit alpha Acyl carrier domain FAS_I_H PF18314.1 EAQ87332.1 - 3.3e-74 248.9 0.1 2.3e-73 246.2 0.0 2.4 3 0 0 3 3 3 1 Fatty acid synthase type I helical domain Ketoacyl-synt_C PF02801.22 EAQ87332.1 - 8.2e-08 32.3 0.0 2.1e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ketoacyl-synt PF00109.26 EAQ87332.1 - 0.00028 20.6 0.0 0.17 11.4 0.0 2.5 1 1 0 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 EAQ87332.1 - 0.0012 18.8 0.2 0.0096 15.9 0.0 2.5 2 0 0 2 2 2 1 KR domain RlaP PF10127.9 EAQ87332.1 - 0.052 13.1 0.4 0.82 9.2 0.0 2.2 2 0 0 2 2 2 0 RNA repair pathway DNA polymerase beta family DUF1729 PF08354.10 EAQ87333.1 - 1.9e-156 520.4 0.0 3.1e-156 519.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) Acyl_transf_1 PF00698.21 EAQ87333.1 - 4.5e-89 299.1 0.0 2.5e-87 293.3 0.0 3.3 4 0 0 4 4 4 1 Acyl transferase domain FAS_meander PF17951.1 EAQ87333.1 - 2e-52 176.9 0.0 5.3e-52 175.5 0.0 1.8 1 0 0 1 1 1 1 Fatty acid synthase meander beta sheet domain FAS_N PF17828.1 EAQ87333.1 - 4.5e-38 130.2 0.0 1e-37 129.0 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta SAT PF16073.5 EAQ87333.1 - 3.4e-37 128.5 0.0 7.9e-37 127.3 0.0 1.6 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis MaoC_dehydratas PF01575.19 EAQ87333.1 - 1.6e-36 124.6 0.0 4.3e-36 123.2 0.0 1.8 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 EAQ87333.1 - 7.2e-26 90.9 0.0 3.5e-25 88.7 0.0 2.3 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase SH3_1 PF00018.28 EAQ87336.1 - 1.9e-11 43.4 0.4 5.6e-11 41.9 0.4 1.9 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EAQ87336.1 - 1.3e-10 41.0 0.8 4.9e-10 39.1 0.5 2.1 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 EAQ87336.1 - 2.4e-09 36.7 0.1 2e-08 33.8 0.1 2.3 2 0 0 2 2 2 1 Variant SH3 domain DNA_pol_phi PF04931.13 EAQ87336.1 - 1.1 7.2 18.7 1.9 6.5 18.7 1.2 1 0 0 1 1 1 0 DNA polymerase phi RPAP2_Rtr1 PF04181.13 EAQ87337.1 - 3.3e-17 62.5 0.1 5.6e-17 61.8 0.1 1.4 1 0 0 1 1 1 1 Rtr1/RPAP2 family FlgD PF03963.14 EAQ87337.1 - 0.16 12.3 4.2 12 6.3 1.4 2.5 2 0 0 2 2 2 0 Flagellar hook capping protein - N-terminal region Ribosomal_S17e PF00833.18 EAQ87338.1 - 6.9e-61 203.6 0.3 8.2e-61 203.3 0.3 1.0 1 0 0 1 1 1 1 Ribosomal S17 Mit_ribos_Mrp51 PF11709.8 EAQ87339.1 - 1.3e-103 347.4 0.3 1.9e-93 314.0 0.0 2.0 1 1 1 2 2 2 2 Mitochondrial ribosomal protein subunit TGT PF01702.18 EAQ87340.1 - 2.7e-140 467.5 0.0 3.3e-140 467.2 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Hist_deacetyl PF00850.19 EAQ87343.1 - 3.1e-50 171.4 0.1 4.8e-50 170.8 0.1 1.3 1 0 0 1 1 1 1 Histone deacetylase domain Abhydrolase_1 PF00561.20 EAQ87344.1 - 3.4e-18 66.2 0.0 2.4e-17 63.4 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EAQ87344.1 - 2.7e-16 60.8 5.4 2.7e-14 54.3 2.1 2.5 2 1 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EAQ87344.1 - 2.1e-15 56.6 0.0 2.1e-14 53.4 0.0 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DUF915 PF06028.11 EAQ87344.1 - 4.8e-06 26.1 0.0 1e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Esterase PF00756.20 EAQ87344.1 - 0.00022 21.0 0.0 0.00047 19.9 0.0 1.5 1 0 0 1 1 1 1 Putative esterase Thioesterase PF00975.20 EAQ87344.1 - 0.017 15.3 0.2 0.079 13.1 0.1 2.1 2 1 0 2 2 2 0 Thioesterase domain Chlorophyllase2 PF12740.7 EAQ87344.1 - 0.065 12.1 0.0 0.22 10.4 0.0 1.7 2 0 0 2 2 2 0 Chlorophyllase enzyme LIDHydrolase PF10230.9 EAQ87344.1 - 0.073 12.6 0.0 0.18 11.3 0.0 1.6 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase Abhydrolase_5 PF12695.7 EAQ87344.1 - 0.075 12.8 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 EAQ87344.1 - 0.17 11.7 0.0 10 5.8 0.0 2.6 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Spo7 PF03907.13 EAQ87345.1 - 7.2e-96 319.9 0.2 9.2e-96 319.6 0.2 1.1 1 0 0 1 1 1 1 Spo7-like protein DSPc PF00782.20 EAQ87346.1 - 4e-14 52.6 0.0 9.5e-14 51.3 0.0 1.6 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 EAQ87346.1 - 0.15 12.4 0.0 0.28 11.5 0.0 1.4 1 0 0 1 1 1 0 Rit1 DUSP-like domain Y_phosphatase PF00102.27 EAQ87346.1 - 0.15 11.6 0.1 0.21 11.1 0.1 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Methyltransf_23 PF13489.6 EAQ87347.1 - 0.0024 17.7 0.0 0.0029 17.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EAQ87347.1 - 0.0049 16.4 0.0 0.0074 15.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.18 EAQ87347.1 - 0.012 14.9 0.0 0.016 14.5 0.0 1.1 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_25 PF13649.6 EAQ87347.1 - 0.07 13.9 0.0 0.18 12.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 EAQ87347.1 - 0.11 12.3 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.17 EAQ87347.1 - 0.14 11.6 0.0 0.22 11.0 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase GidB PF02527.15 EAQ87347.1 - 0.16 11.3 0.0 0.22 10.8 0.0 1.1 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G DUF938 PF06080.12 EAQ87347.1 - 0.21 11.3 0.0 0.32 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Abhydrolase_1 PF00561.20 EAQ87348.1 - 6.5e-49 166.9 0.0 1.1e-48 166.1 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EAQ87348.1 - 0.00076 20.2 4.9 0.0018 19.0 4.9 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family THOC2_N PF16134.5 EAQ87349.1 - 2.7e-210 700.3 0.0 1.1e-207 691.7 0.0 2.2 1 1 0 1 1 1 1 THO complex subunit 2 N-terminus Tho2 PF11262.8 EAQ87349.1 - 5.2e-94 314.8 0.3 7.1e-94 314.4 0.3 1.2 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.8 EAQ87349.1 - 8.4e-29 99.5 0.1 1.7e-28 98.5 0.1 1.6 1 0 0 1 1 1 1 Transcription- and export-related complex subunit WSC PF01822.19 EAQ87350.1 - 5.3e-13 49.0 3.2 1.2e-12 47.8 3.2 1.6 1 0 0 1 1 1 1 WSC domain Syndecan PF01034.20 EAQ87350.1 - 2.1e-05 24.3 0.0 3.9e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Syndecan domain DUF4690 PF15756.5 EAQ87350.1 - 2.4e-05 24.9 1.1 5.2e-05 23.8 1.1 1.6 1 0 0 1 1 1 1 Small Novel Rich in Cartilage Gram_pos_anchor PF00746.21 EAQ87350.1 - 0.0072 16.2 0.0 0.0072 16.2 0.0 2.3 3 0 0 3 3 3 1 LPXTG cell wall anchor motif PTP_tm PF18861.1 EAQ87350.1 - 0.012 15.6 0.3 0.019 15.0 0.3 1.3 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J Adeno_E3_CR2 PF02439.15 EAQ87350.1 - 0.027 14.2 0.9 0.059 13.1 0.1 1.9 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 SKG6 PF08693.10 EAQ87350.1 - 4.5 6.8 8.5 9.7 5.7 8.5 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain SKG6 PF08693.10 EAQ87351.1 - 0.016 14.6 1.5 0.037 13.4 0.0 2.4 2 0 0 2 2 2 0 Transmembrane alpha-helix domain YajC PF02699.15 EAQ87351.1 - 0.18 11.7 0.1 1.3 9.0 0.0 2.1 2 0 0 2 2 2 0 Preprotein translocase subunit MAD PF05557.13 EAQ87351.1 - 6.5 5.0 7.7 1.2 7.4 1.2 2.0 2 0 0 2 2 2 0 Mitotic checkpoint protein RSN1_7TM PF02714.15 EAQ87352.1 - 1.3e-89 300.1 27.9 1.3e-89 300.1 27.9 2.2 4 0 0 4 4 4 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 EAQ87352.1 - 2e-45 154.3 0.8 2e-45 154.3 0.8 3.2 3 1 0 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 EAQ87352.1 - 6.5e-37 127.4 0.0 9.8e-37 126.9 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 EAQ87352.1 - 1.6e-32 111.6 0.0 4.2e-32 110.2 0.0 1.7 2 0 0 2 2 2 1 Extracellular tail, of 10TM putative phosphate transporter GMC_oxred_N PF00732.19 EAQ87353.1 - 5e-51 173.8 0.0 1.9e-24 86.6 0.0 2.3 1 1 1 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.13 EAQ87353.1 - 2.5e-21 76.7 0.1 6.5e-21 75.4 0.1 1.7 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 EAQ87353.1 - 0.035 14.3 0.1 0.035 14.3 0.1 2.2 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EAQ87353.1 - 0.04 13.0 0.0 0.059 12.4 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Fungal_trans PF04082.18 EAQ87354.1 - 5.2e-16 58.5 0.0 1.5e-15 57.0 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EAQ87354.1 - 1.9e-09 37.5 8.9 3.8e-09 36.5 8.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4551 PF15087.6 EAQ87354.1 - 4.5 6.0 8.7 9 5.0 8.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Senescence PF06911.12 EAQ87356.1 - 1.1e-59 201.9 3.1 1.6e-59 201.3 3.1 1.3 1 0 0 1 1 1 1 Senescence-associated protein GCP_N_terminal PF17681.1 EAQ87357.1 - 8.9e-24 84.7 0.0 1.7e-23 83.7 0.0 1.5 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 EAQ87357.1 - 4.7e-19 69.0 0.0 2e-18 66.9 0.0 1.8 1 1 0 1 1 1 1 Gamma tubulin complex component C-terminal TerB_C PF15615.6 EAQ87357.1 - 0.028 14.7 0.5 1.9 8.8 0.1 2.6 2 0 0 2 2 2 0 TerB-C domain Serglycin PF04360.12 EAQ87357.1 - 0.14 12.1 5.8 0.28 11.1 5.8 1.5 1 0 0 1 1 1 0 Serglycin ORC4_C PF14629.6 EAQ87357.1 - 0.49 9.7 2.1 0.96 8.8 2.1 1.4 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 4 C-terminus FAR1 PF03101.15 EAQ87358.1 - 0.0001 22.9 0.2 0.00021 21.9 0.2 1.5 1 0 0 1 1 1 1 FAR1 DNA-binding domain COG2 PF06148.11 EAQ87358.1 - 0.14 12.2 0.3 1.8 8.6 0.9 2.2 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4200 PF13863.6 EAQ87358.1 - 1.1 9.7 9.3 2 8.8 9.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) AAA_6 PF12774.7 EAQ87359.1 - 1.2e-125 418.9 0.0 6.9e-125 416.4 0.0 2.4 3 0 0 3 3 2 1 Hydrolytic ATP binding site of dynein motor region AAA_9 PF12781.7 EAQ87359.1 - 3.8e-73 245.2 0.7 3.8e-73 245.2 0.7 3.8 4 0 0 4 4 3 1 ATP-binding dynein motor region AAA_8 PF12780.7 EAQ87359.1 - 1.6e-65 221.0 0.0 1.5e-64 217.8 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_7 PF12775.7 EAQ87359.1 - 5.5e-43 146.6 0.0 2.2e-36 125.0 0.0 4.8 5 0 0 5 5 5 2 P-loop containing dynein motor region MT PF12777.7 EAQ87359.1 - 1.8e-38 132.4 7.8 3.1e-38 131.7 7.8 1.3 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.14 EAQ87359.1 - 3.7e-33 114.4 0.1 6.4e-12 45.6 0.0 6.7 5 1 0 5 5 5 4 AAA domain (dynein-related subfamily) Dynein_heavy PF03028.15 EAQ87359.1 - 6.4e-30 103.7 0.0 5.7e-28 97.4 0.0 3.0 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain AAA_22 PF13401.6 EAQ87359.1 - 6e-17 62.2 0.4 0.005 17.1 0.0 5.8 5 0 0 5 5 4 3 AAA domain AAA PF00004.29 EAQ87359.1 - 4e-14 53.2 0.0 0.0011 19.3 0.0 4.7 4 0 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) Dynein_AAA_lid PF17852.1 EAQ87359.1 - 4.2e-13 49.5 0.0 1.4e-12 47.8 0.0 1.9 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_16 PF13191.6 EAQ87359.1 - 2.3e-11 44.4 0.2 0.93 9.9 0.0 6.4 6 0 0 6 6 5 3 AAA ATPase domain AAA_33 PF13671.6 EAQ87359.1 - 8.5e-11 42.2 0.6 0.19 11.9 0.0 5.0 4 0 0 4 4 4 3 AAA domain AAA_18 PF13238.6 EAQ87359.1 - 2.9e-10 40.8 0.3 0.042 14.4 0.0 5.3 4 0 0 4 4 4 2 AAA domain AAA_lid_11 PF18198.1 EAQ87359.1 - 3.8e-08 33.3 0.0 9.5e-08 32.0 0.0 1.7 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_29 PF13555.6 EAQ87359.1 - 9.8e-07 28.4 0.0 0.29 10.9 0.0 3.8 3 0 0 3 3 3 2 P-loop containing region of AAA domain T2SSE PF00437.20 EAQ87359.1 - 2.4e-06 26.8 0.0 0.012 14.7 0.0 3.6 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_14 PF13173.6 EAQ87359.1 - 1.2e-05 25.3 0.0 1.1 9.4 0.0 4.3 4 0 0 4 4 3 2 AAA domain Mg_chelatase PF01078.21 EAQ87359.1 - 2.2e-05 24.0 3.8 0.35 10.2 0.0 4.6 5 0 0 5 5 4 1 Magnesium chelatase, subunit ChlI AAA_lid_1 PF17857.1 EAQ87359.1 - 2.9e-05 24.2 0.2 0.00022 21.4 0.0 2.7 2 0 0 2 2 1 1 AAA+ lid domain AAA_19 PF13245.6 EAQ87359.1 - 6.2e-05 23.4 0.6 0.14 12.4 0.0 4.4 4 0 0 4 4 4 1 AAA domain AAA_30 PF13604.6 EAQ87359.1 - 0.00012 21.9 0.2 20 4.8 0.0 4.6 4 0 0 4 4 4 0 AAA domain ABC_tran PF00005.27 EAQ87359.1 - 0.00018 22.0 2.7 2.2 8.8 0.0 4.7 4 0 0 4 4 3 1 ABC transporter AAA_25 PF13481.6 EAQ87359.1 - 0.00043 19.9 1.2 0.12 11.9 0.0 3.4 4 0 0 4 4 2 1 AAA domain AAA_24 PF13479.6 EAQ87359.1 - 0.00049 19.9 0.1 5.6 6.6 0.0 3.9 4 0 0 4 4 4 0 AAA domain IstB_IS21 PF01695.17 EAQ87359.1 - 0.0006 19.6 0.3 0.33 10.7 0.0 4.1 4 0 0 4 4 4 1 IstB-like ATP binding protein CLZ PF16526.5 EAQ87359.1 - 0.00078 19.8 1.6 0.00078 19.8 1.6 3.5 3 1 0 3 3 1 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels FtsK_SpoIIIE PF01580.18 EAQ87359.1 - 0.0013 18.2 3.7 1.5 8.1 0.0 4.3 4 0 0 4 4 4 1 FtsK/SpoIIIE family Zeta_toxin PF06414.12 EAQ87359.1 - 0.0017 17.7 0.0 2.2 7.5 0.0 3.8 3 0 0 3 3 3 1 Zeta toxin RNA_helicase PF00910.22 EAQ87359.1 - 0.002 18.5 0.1 23 5.4 0.0 4.5 4 0 0 4 4 4 0 RNA helicase Rad17 PF03215.15 EAQ87359.1 - 0.0089 16.0 0.1 3.5 7.5 0.0 3.7 4 0 0 4 4 4 1 Rad17 P-loop domain NTPase_1 PF03266.15 EAQ87359.1 - 0.016 15.2 1.0 20 5.0 0.0 4.4 4 0 0 4 4 4 0 NTPase NACHT PF05729.12 EAQ87359.1 - 0.026 14.5 4.2 17 5.3 0.0 4.8 6 0 0 6 6 4 0 NACHT domain Spc7 PF08317.11 EAQ87359.1 - 0.035 13.0 31.7 0.035 13.0 13.5 3.3 3 0 0 3 3 3 0 Spc7 kinetochore protein DUF3867 PF12983.7 EAQ87359.1 - 0.045 13.8 7.0 0.13 12.3 2.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3867) AAA_28 PF13521.6 EAQ87359.1 - 0.049 13.9 1.6 26 5.0 0.0 4.4 5 0 0 5 5 3 0 AAA domain RuvB_N PF05496.12 EAQ87359.1 - 0.05 13.3 0.0 2.9 7.6 0.0 3.0 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain DUF4482 PF14818.6 EAQ87359.1 - 0.064 14.1 10.6 7.7 7.4 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4482) MMR_HSR1 PF01926.23 EAQ87359.1 - 0.076 13.1 0.7 6.5 6.9 0.0 3.9 4 0 0 4 4 3 0 50S ribosome-binding GTPase SRP54 PF00448.22 EAQ87359.1 - 0.17 11.5 0.9 44 3.6 0.1 4.1 4 0 0 4 4 4 0 SRP54-type protein, GTPase domain cobW PF02492.19 EAQ87359.1 - 0.21 11.2 0.7 28 4.3 0.0 3.4 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 EAQ87359.1 - 0.23 11.2 1.4 6 6.6 0.1 3.6 4 0 0 4 4 4 0 Ethanolamine utilisation - propanediol utilisation Pil1 PF13805.6 EAQ87359.1 - 0.75 9.2 22.0 0.01 15.3 0.7 2.5 2 0 0 2 2 2 0 Eisosome component PIL1 AAA_11 PF13086.6 EAQ87359.1 - 0.82 9.4 0.0 0.82 9.4 0.0 4.1 4 1 0 4 4 2 0 AAA domain Taxilin PF09728.9 EAQ87359.1 - 1.7 7.8 29.4 0.042 13.0 21.4 2.2 2 1 0 2 2 2 0 Myosin-like coiled-coil protein MbeB_N PF04837.12 EAQ87359.1 - 4.5 7.6 8.3 1.3 9.4 0.1 3.4 3 0 0 3 3 2 0 MbeB-like, N-term conserved region Phage_GP20 PF06810.11 EAQ87359.1 - 6.4 6.6 21.7 1.1 9.1 8.1 3.1 3 1 0 3 3 2 0 Phage minor structural protein GP20 PHP PF02811.19 EAQ87360.1 - 9.8e-09 35.7 0.0 4.3e-08 33.6 0.0 1.9 1 1 0 1 1 1 1 PHP domain Dynamin_M PF01031.20 EAQ87361.1 - 2.4e-23 82.8 0.2 5.1e-20 71.9 0.0 2.9 4 0 0 4 4 4 2 Dynamin central region GED PF02212.18 EAQ87361.1 - 0.00031 20.8 0.4 0.001 19.2 0.0 2.1 2 0 0 2 2 2 1 Dynamin GTPase effector domain FAA_hydrolase_N PF09298.11 EAQ87361.1 - 0.011 15.9 0.1 0.033 14.4 0.1 1.9 1 0 0 1 1 1 0 Fumarylacetoacetase N-terminal Dynamin_N PF00350.23 EAQ87361.1 - 0.018 15.1 0.0 0.04 14.0 0.0 1.6 1 0 0 1 1 1 0 Dynamin family DUF1539 PF07560.11 EAQ87361.1 - 0.089 12.9 0.0 2.2 8.3 0.0 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1539) Gp49 PF05973.14 EAQ87361.1 - 0.089 12.9 0.0 2.3 8.4 0.0 2.5 2 0 0 2 2 2 0 Phage derived protein Gp49-like (DUF891) Fungal_trans PF04082.18 EAQ87362.1 - 1.1e-27 96.7 0.0 2.3e-27 95.7 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Clr5 PF14420.6 EAQ87364.1 - 4.3e-08 33.3 1.2 7.3e-08 32.5 1.2 1.4 1 0 0 1 1 1 1 Clr5 domain DUF1774 PF08611.10 EAQ87365.1 - 3.1e-18 65.9 3.6 3.1e-18 65.9 3.6 3.0 3 1 0 3 3 3 1 Fungal protein of unknown function (DUF1774) UvrD_C_2 PF13538.6 EAQ87366.1 - 0.016 15.0 0.0 0.043 13.7 0.0 1.7 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain zf-RVT PF13966.6 EAQ87368.1 - 0.092 13.5 0.9 0.28 11.9 0.2 2.2 2 1 0 2 2 2 0 zinc-binding in reverse transcriptase PQQ PF01011.21 EAQ87370.1 - 1.3e-05 24.9 5.9 0.33 11.0 0.1 4.8 5 0 0 5 5 5 3 PQQ enzyme repeat PQQ_2 PF13360.6 EAQ87370.1 - 2.5e-05 24.0 0.4 0.26 10.8 0.0 3.1 2 2 0 2 2 2 2 PQQ-like domain PQQ_3 PF13570.6 EAQ87370.1 - 7.1e-05 23.2 4.1 0.13 12.7 0.0 4.5 5 0 0 5 5 5 2 PQQ-like domain SNF2_N PF00176.23 EAQ87371.1 - 3e-36 124.9 0.4 7.8e-36 123.5 0.4 1.5 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EAQ87371.1 - 1.2e-12 48.2 0.0 2.4e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.6 EAQ87371.1 - 1.5e-05 24.7 12.8 2.9e-05 23.8 12.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EAQ87371.1 - 2e-05 24.3 10.7 3.4e-05 23.6 10.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EAQ87371.1 - 3.5e-05 23.6 13.9 6.6e-05 22.7 13.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.15 EAQ87371.1 - 7.4e-05 22.8 0.1 0.00061 19.8 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-RING_5 PF14634.6 EAQ87371.1 - 0.00032 20.6 12.8 0.00063 19.6 12.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 EAQ87371.1 - 0.0018 18.5 7.4 0.0053 17.0 7.4 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 EAQ87371.1 - 0.0024 18.2 13.2 0.0046 17.3 13.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_10 PF16685.5 EAQ87371.1 - 0.012 15.7 6.6 0.033 14.3 6.6 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 Prok-RING_4 PF14447.6 EAQ87371.1 - 0.013 15.3 11.5 0.025 14.4 11.5 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 EAQ87371.1 - 0.015 15.4 10.8 0.033 14.3 10.8 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 EAQ87371.1 - 0.056 13.5 12.3 0.13 12.3 12.3 1.6 1 0 0 1 1 1 0 RING-type zinc-finger Sulfotransfer_4 PF17784.1 EAQ87371.1 - 0.093 12.5 0.1 0.25 11.2 0.1 1.7 1 0 0 1 1 1 0 Sulfotransferase domain TackOD1 PF18551.1 EAQ87371.1 - 0.12 12.1 2.9 0.27 10.9 2.9 1.5 1 0 0 1 1 1 0 Thaumarchaeal output domain 1 zf-RING_6 PF14835.6 EAQ87371.1 - 0.2 11.6 5.3 0.45 10.4 5.3 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DUF1272 PF06906.11 EAQ87371.1 - 1.3 9.2 7.8 3.4 7.8 7.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-RING_4 PF14570.6 EAQ87371.1 - 8.6 6.2 9.9 19 5.1 9.9 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Ank_2 PF12796.7 EAQ87372.1 - 1.9e-25 89.3 13.9 2e-05 25.1 0.1 12.0 8 2 6 14 14 14 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAQ87372.1 - 5.8e-17 61.8 9.3 0.0032 18.0 0.0 11.7 13 1 1 14 14 14 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAQ87372.1 - 1.6e-13 49.4 9.6 0.69 10.7 0.0 14.3 17 0 0 17 17 17 1 Ankyrin repeat Ank_5 PF13857.6 EAQ87372.1 - 9.6e-05 22.6 7.9 0.027 14.8 0.0 7.8 9 1 1 10 10 10 1 Ankyrin repeats (many copies) Ank PF00023.30 EAQ87372.1 - 0.00021 21.6 26.4 0.14 12.6 0.0 12.1 15 0 0 15 15 15 2 Ankyrin repeat Caldesmon PF02029.15 EAQ87372.1 - 4 6.1 28.3 6.8 5.3 28.3 1.3 1 0 0 1 1 1 0 Caldesmon XRN_M PF17846.1 EAQ87372.1 - 5.5 5.8 9.6 8.7 5.2 9.6 1.2 1 0 0 1 1 1 0 Xrn1 helical domain HET PF06985.11 EAQ87373.1 - 6e-30 104.5 0.0 1e-29 103.8 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) FAD_binding_4 PF01565.23 EAQ87374.1 - 1.1e-12 47.9 0.0 1.8e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain ABC2_membrane PF01061.24 EAQ87375.1 - 1e-20 74.0 17.9 1.6e-20 73.4 17.9 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 EAQ87375.1 - 4.5e-20 72.6 0.0 8.2e-20 71.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_25 PF13481.6 EAQ87375.1 - 2.2e-05 24.1 0.1 7.9e-05 22.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EAQ87375.1 - 0.00016 22.1 0.3 0.00028 21.3 0.0 1.6 2 0 0 2 2 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 EAQ87375.1 - 0.002 18.0 0.0 0.0034 17.3 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 EAQ87375.1 - 0.0079 16.5 0.0 0.034 14.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 EAQ87375.1 - 0.027 14.9 0.0 0.17 12.3 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 EAQ87375.1 - 0.029 14.3 0.0 0.051 13.5 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_28 PF13521.6 EAQ87375.1 - 0.049 13.9 0.0 0.093 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EAQ87375.1 - 0.051 13.3 0.1 0.099 12.4 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_21 PF13304.6 EAQ87375.1 - 0.052 13.3 0.0 11 5.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_13 PF13166.6 EAQ87375.1 - 0.059 12.0 0.0 1.3 7.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EAQ87375.1 - 0.08 13.1 0.1 0.29 11.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF2791 PF10923.8 EAQ87375.1 - 0.1 11.4 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) NACHT PF05729.12 EAQ87375.1 - 0.12 12.3 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.22 EAQ87375.1 - 0.12 12.8 0.0 0.24 11.8 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 EAQ87375.1 - 0.13 12.0 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 EAQ87375.1 - 0.15 12.2 0.0 0.36 10.9 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase SMC_N PF02463.19 EAQ87375.1 - 0.21 11.0 0.0 14 5.0 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain PDR_CDR PF06422.12 EAQ87375.1 - 1 9.3 0.0 1 9.3 0.0 2.7 3 1 1 4 4 3 0 CDR ABC transporter FA_hydroxylase PF04116.13 EAQ87376.1 - 3.2e-07 30.8 8.5 5e-07 30.1 5.4 2.6 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily Catalase PF00199.19 EAQ87377.1 - 2.4e-122 408.7 0.1 2.6e-76 257.2 0.0 3.0 1 1 2 3 3 3 3 Catalase Augurin PF15187.6 EAQ87377.1 - 0.76 10.0 2.6 21 5.3 0.1 2.4 2 0 0 2 2 2 0 Oesophageal cancer-related gene 4 Methyltransf_33 PF10017.9 EAQ87378.1 - 2.6e-62 210.7 0.0 3.5e-62 210.3 0.0 1.2 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent Glyco_hydro_43 PF04616.14 EAQ87379.1 - 1.5e-35 122.9 1.0 1.1e-23 84.0 0.2 2.0 1 1 1 2 2 2 2 Glycosyl hydrolases family 43 COPI_assoc PF08507.10 EAQ87379.1 - 0.14 12.2 0.1 0.84 9.7 0.0 2.0 2 0 0 2 2 2 0 COPI associated protein COesterase PF00135.28 EAQ87380.1 - 2.5e-77 260.9 0.0 9.6e-77 259.0 0.0 1.7 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EAQ87380.1 - 4.3e-06 26.7 0.1 8.1e-06 25.8 0.1 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold APH PF01636.23 EAQ87381.1 - 0.055 13.4 0.1 0.09 12.7 0.1 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family DUF2852 PF11014.8 EAQ87382.1 - 0.0014 18.8 1.4 0.041 14.0 0.3 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF2852) ADH_zinc_N PF00107.26 EAQ87383.1 - 1.5e-25 89.6 1.1 3.1e-25 88.6 1.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EAQ87383.1 - 2.2e-20 74.1 0.2 4.2e-20 73.2 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EAQ87383.1 - 1.7e-06 27.9 0.0 4.1e-06 26.6 0.0 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 EAQ87383.1 - 0.0059 16.5 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase Epimerase PF01370.21 EAQ87384.1 - 3.3e-46 157.7 0.0 4.2e-46 157.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EAQ87384.1 - 3.4e-44 151.6 0.0 5.8e-44 150.9 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EAQ87384.1 - 2.3e-14 53.1 0.0 6.2e-14 51.7 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 EAQ87384.1 - 2.1e-12 46.8 0.0 3.5e-09 36.2 0.0 2.1 1 1 1 2 2 2 2 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 EAQ87384.1 - 2.1e-10 40.2 0.0 2.9e-10 39.7 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 EAQ87384.1 - 2.8e-07 30.2 0.0 4.3e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EAQ87384.1 - 1.8e-06 28.0 0.0 3.6e-06 27.0 0.0 1.4 1 1 0 1 1 1 1 KR domain NAD_binding_4 PF07993.12 EAQ87384.1 - 7.9e-06 25.2 0.0 0.00019 20.7 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 EAQ87384.1 - 0.001 19.0 0.0 0.0015 18.4 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding adh_short_C2 PF13561.6 EAQ87384.1 - 0.0056 16.3 0.0 0.0083 15.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NmrA PF05368.13 EAQ87384.1 - 0.027 14.0 0.0 0.17 11.4 0.0 2.0 2 0 0 2 2 2 0 NmrA-like family UDPG_MGDP_dh_N PF03721.14 EAQ87384.1 - 0.051 13.2 0.3 0.085 12.4 0.3 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Sad1_UNC PF07738.13 EAQ87385.1 - 3.6e-10 40.0 0.0 0.00049 20.1 0.0 2.3 2 0 0 2 2 2 2 Sad1 / UNC-like C-terminal DEAD PF00270.29 EAQ87386.1 - 4.1e-46 157.0 0.0 7.4e-46 156.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EAQ87386.1 - 1.2e-22 80.3 0.0 4.5e-22 78.5 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EAQ87386.1 - 1.1e-19 70.4 0.0 2.9e-19 69.0 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 EAQ87386.1 - 2.6e-07 30.8 0.1 2.5e-06 27.6 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF3298 PF11738.8 EAQ87386.1 - 0.46 11.5 2.0 0.81 10.8 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3298) Transp_cyt_pur PF02133.15 EAQ87387.1 - 5e-148 493.5 34.3 5.7e-148 493.3 34.3 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DDE_1 PF03184.19 EAQ87389.1 - 7.5e-24 84.3 0.1 7.8e-23 81.0 0.1 2.2 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 EAQ87389.1 - 2.1e-09 37.3 0.0 5.2e-09 36.0 0.0 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.16 EAQ87389.1 - 5.1e-06 26.1 0.0 1e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 helix-turn-helix, Psq domain DDE_3 PF13358.6 EAQ87389.1 - 0.002 17.9 0.1 0.0041 16.9 0.1 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease YlqD PF11068.8 EAQ87389.1 - 0.13 12.7 7.7 0.25 11.7 7.7 1.4 1 0 0 1 1 1 0 YlqD protein Phage_lysozyme2 PF18013.1 EAQ87389.1 - 0.59 10.1 2.4 1.7 8.7 1.6 2.1 2 0 0 2 2 2 0 Phage tail lysozyme DUF4200 PF13863.6 EAQ87389.1 - 1.1 9.6 10.1 2 8.8 10.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) OPT PF03169.15 EAQ87390.1 - 3.5e-94 316.6 31.5 2.3e-59 201.6 18.8 2.0 1 1 1 2 2 2 2 OPT oligopeptide transporter protein DIE2_ALG10 PF04922.12 EAQ87391.1 - 7.9e-93 311.9 9.2 1.4e-92 311.1 9.2 1.3 1 1 0 1 1 1 1 DIE2/ALG10 family QCR10 PF09796.9 EAQ87392.1 - 1.2e-26 92.5 0.6 1.5e-26 92.2 0.6 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Med4 PF10018.9 EAQ87393.1 - 5.6e-63 212.2 8.0 7.1e-63 211.8 8.0 1.1 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 TFIIA PF03153.13 EAQ87393.1 - 1.2 9.0 9.8 2.1 8.2 9.7 1.4 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit EMP70 PF02990.16 EAQ87395.1 - 7.7e-204 678.2 3.5 1.2e-203 677.6 3.5 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 Sas10_Utp3 PF04000.15 EAQ87396.1 - 2e-17 63.6 0.9 2e-17 63.6 0.9 1.8 2 0 0 2 2 2 1 Sas10/Utp3/C1D family Dsh_C PF12316.8 EAQ87396.1 - 0.14 12.6 1.4 0.34 11.3 1.4 1.6 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal DNA_pol_phi PF04931.13 EAQ87396.1 - 0.31 9.1 4.2 0.45 8.6 4.2 1.2 1 0 0 1 1 1 0 DNA polymerase phi FMO-like PF00743.19 EAQ87397.1 - 3.9e-16 58.6 0.0 2.8e-15 55.7 0.0 2.0 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EAQ87397.1 - 4.9e-15 55.6 0.0 6.2e-12 45.4 0.0 3.0 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EAQ87397.1 - 6.8e-12 45.2 0.0 6.8e-10 38.7 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EAQ87397.1 - 3.1e-09 36.4 0.0 5.8e-07 29.0 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 EAQ87397.1 - 1.2e-06 28.6 0.5 1.4e-05 25.2 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EAQ87397.1 - 5.9e-06 26.8 1.8 0.048 14.2 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EAQ87397.1 - 1.2e-05 25.0 2.4 3.5e-05 23.6 2.4 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 EAQ87397.1 - 0.00054 19.3 0.0 0.081 12.2 0.0 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 EAQ87397.1 - 0.00063 19.8 0.0 0.22 11.6 0.0 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 EAQ87397.1 - 0.0029 17.5 0.1 0.0051 16.7 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.6 EAQ87397.1 - 0.003 17.6 2.4 0.13 12.2 0.1 3.5 4 0 0 4 4 4 1 FAD-NAD(P)-binding NAD_binding_7 PF13241.6 EAQ87397.1 - 0.042 14.3 0.0 3.2 8.2 0.0 2.4 2 1 0 2 2 2 0 Putative NAD(P)-binding HI0933_like PF03486.14 EAQ87397.1 - 0.065 11.9 1.5 0.27 9.9 0.2 2.1 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_2 PF00890.24 EAQ87397.1 - 0.12 11.4 2.9 0.14 11.3 0.5 1.9 2 0 0 2 2 2 0 FAD binding domain GIDA PF01134.22 EAQ87397.1 - 0.33 10.0 2.2 0.42 9.6 0.3 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A Phytase PF02333.15 EAQ87398.1 - 7e-26 91.1 0.2 9.2e-24 84.1 0.0 2.4 2 0 0 2 2 2 2 Phytase EGF_2 PF07974.13 EAQ87398.1 - 8.2e-09 35.7 40.5 6.9e-05 23.1 15.8 2.6 2 0 0 2 2 2 2 EGF-like domain EGF PF00008.27 EAQ87398.1 - 0.0096 16.2 8.2 0.0096 16.2 8.2 2.5 2 0 0 2 2 2 1 EGF-like domain Chitin_bind_1 PF00187.19 EAQ87399.1 - 4e-10 40.0 13.1 4e-10 40.0 13.1 2.6 2 0 0 2 2 2 2 Chitin recognition protein 2-Hacid_dh_C PF02826.19 EAQ87400.1 - 3e-47 160.3 0.0 5.1e-47 159.5 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DcpS_C PF11969.8 EAQ87400.1 - 3.3e-18 66.2 0.5 6e-18 65.4 0.5 1.5 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 EAQ87400.1 - 6.2e-06 26.9 0.2 1.6e-05 25.6 0.2 1.7 1 0 0 1 1 1 1 HIT domain F420_oxidored PF03807.17 EAQ87400.1 - 0.0013 19.3 0.0 0.0028 18.2 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent AlaDh_PNT_C PF01262.21 EAQ87400.1 - 0.042 13.1 0.0 0.072 12.4 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Sacchrp_dh_NADP PF03435.18 EAQ87400.1 - 0.18 12.1 0.0 0.37 11.0 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain MFS_1 PF07690.16 EAQ87401.1 - 5.7e-23 81.4 23.1 9.4e-23 80.7 23.1 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 EAQ87401.1 - 0.00012 20.7 6.6 0.00016 20.3 6.6 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 EAQ87401.1 - 0.0003 19.8 4.9 0.00041 19.3 4.9 1.1 1 0 0 1 1 1 1 MFS_1 like family ATG22 PF11700.8 EAQ87401.1 - 0.0029 16.3 4.3 0.0029 16.3 4.3 2.0 2 0 0 2 2 2 1 Vacuole effluxer Atg22 like OATP PF03137.20 EAQ87401.1 - 0.0095 14.3 4.7 0.014 13.8 4.7 1.2 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family zf-BED PF02892.15 EAQ87402.1 - 0.0016 18.4 1.2 0.0036 17.3 0.4 2.1 2 0 0 2 2 2 1 BED zinc finger DUF4174 PF13778.6 EAQ87402.1 - 0.019 15.5 0.0 0.041 14.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4174) zf-RING_10 PF16685.5 EAQ87402.1 - 0.034 14.3 0.1 0.079 13.1 0.1 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 7tm_4 PF13853.6 EAQ87402.1 - 0.058 13.1 0.0 0.096 12.4 0.0 1.2 1 0 0 1 1 1 0 Olfactory receptor Glycoprot_B_PH2 PF17417.2 EAQ87402.1 - 0.087 13.2 0.1 0.26 11.6 0.1 1.8 1 0 0 1 1 1 0 Herpesvirus Glycoprotein B PH-like domain DUF1660 PF07874.11 EAQ87402.1 - 0.17 12.4 0.8 4.3 7.9 0.1 2.7 2 0 0 2 2 2 0 Prophage protein (DUF1660) Abhydrolase_3 PF07859.13 EAQ87403.1 - 9e-17 61.6 0.0 1.9e-16 60.6 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 EAQ87403.1 - 0.04 12.8 0.0 0.091 11.6 0.0 1.5 2 0 0 2 2 2 0 Carboxylesterase family DUF1996 PF09362.10 EAQ87405.1 - 1.2e-80 270.9 1.1 1.6e-80 270.5 1.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) KGG PF10685.9 EAQ87406.1 - 1.1e-18 66.9 2.0 2e-11 43.7 0.5 2.1 2 0 0 2 2 2 2 Stress-induced bacterial acidophilic repeat motif Amidoligase_2 PF12224.8 EAQ87407.1 - 6.7e-13 48.9 0.0 2.2e-12 47.2 0.0 1.8 1 1 0 1 1 1 1 Putative amidoligase enzyme DUF3931 PF13082.6 EAQ87407.1 - 0.068 13.3 0.1 0.13 12.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3931) zf-CCHC PF00098.23 EAQ87409.1 - 3.8e-05 23.6 3.4 3.8e-05 23.6 3.4 3.3 4 0 0 4 4 4 1 Zinc knuckle zf-CCHC_4 PF14392.6 EAQ87409.1 - 1.5 8.6 7.9 0.43 10.4 0.4 2.7 2 0 0 2 2 2 0 Zinc knuckle DJ-1_PfpI PF01965.24 EAQ87410.1 - 1.2e-16 61.0 0.0 2.1e-16 60.1 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family HOOK PF05622.12 EAQ87410.1 - 0.12 10.5 1.2 0.17 10.0 1.2 1.0 1 0 0 1 1 1 0 HOOK protein Dicty_CAR PF05462.11 EAQ87411.1 - 0.00027 20.2 2.7 0.00027 20.2 2.7 1.9 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor Git3 PF11710.8 EAQ87411.1 - 0.00036 20.4 2.6 0.00063 19.6 2.6 1.3 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.21 EAQ87411.1 - 0.03 13.7 3.1 0.062 12.6 3.1 1.5 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Pex14_N PF04695.13 EAQ87411.1 - 0.043 14.5 0.9 0.077 13.6 0.9 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region 7tm_2 PF00002.24 EAQ87411.1 - 1.1 8.5 6.1 2.2 7.5 6.1 1.5 1 0 0 1 1 1 0 7 transmembrane receptor (Secretin family) DUF4732 PF15876.5 EAQ87412.1 - 0.074 13.1 0.0 0.1 12.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4732) UDPG_MGDP_dh_C PF03720.15 EAQ87415.1 - 0.14 12.6 0.2 0.38 11.2 0.2 1.7 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Turandot PF07240.11 EAQ87416.1 - 0.048 13.6 0.8 0.1 12.6 0.8 1.5 1 0 0 1 1 1 0 Stress-inducible humoral factor Turandot Pyr_redox PF00070.27 EAQ87416.1 - 0.085 13.4 0.1 0.25 11.9 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase COesterase PF00135.28 EAQ87420.1 - 1.2e-75 255.3 0.0 2.2e-75 254.5 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EAQ87420.1 - 1.5e-11 44.6 0.0 6.8e-11 42.4 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EAQ87420.1 - 1.9e-06 27.5 0.1 3.3e-06 26.7 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family RVT_2 PF07727.14 EAQ87421.1 - 4.6e-44 150.9 0.0 8.6e-44 150.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 EAQ87421.1 - 4e-08 33.5 0.0 1e-07 32.2 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.6 EAQ87421.1 - 0.0027 17.5 0.0 0.0077 16.1 0.0 1.8 1 0 0 1 1 1 1 GAG-pre-integrase domain Retrotran_gag_2 PF14223.6 EAQ87421.1 - 0.017 14.8 0.6 0.042 13.5 0.6 1.6 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type PolC_DP2 PF03833.13 EAQ87421.1 - 0.46 8.3 3.2 0.71 7.7 3.2 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zinc_ribbon_15 PF17032.5 EAQ87421.1 - 8.8 7.2 7.7 4.2 8.2 3.6 2.3 2 0 0 2 2 2 0 zinc-ribbon family Tyrosinase PF00264.20 EAQ87422.1 - 5.3e-50 170.8 0.0 8.1e-50 170.2 0.0 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase DUF456 PF04306.13 EAQ87423.1 - 0.047 14.0 0.8 0.047 14.0 0.8 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF456) Glyco_hydro_16 PF00722.21 EAQ87424.1 - 3.8e-16 59.1 0.4 1.5e-15 57.1 0.4 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.15 EAQ87424.1 - 2.2e-05 23.1 6.6 0.011 14.2 0.1 2.1 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) DUF2401 PF10287.9 EAQ87424.1 - 0.01 15.5 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 0 Putative TOS1-like glycosyl hydrolase (DUF2401) Abhydrolase_3 PF07859.13 EAQ87425.1 - 2e-22 80.1 0.0 7.4e-19 68.4 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EAQ87425.1 - 8.6e-10 38.4 0.0 5.2e-05 22.8 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Chlorophyllase2 PF12740.7 EAQ87425.1 - 0.0061 15.5 0.0 0.0095 14.9 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_4 PF08386.10 EAQ87425.1 - 0.038 14.1 0.0 0.071 13.2 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein Say1_Mug180 PF10340.9 EAQ87425.1 - 0.041 12.7 0.2 0.2 10.5 0.2 1.8 1 1 0 1 1 1 0 Steryl acetyl hydrolase COesterase PF00135.28 EAQ87425.1 - 0.049 12.5 0.1 0.21 10.4 0.1 1.8 1 1 0 1 1 1 0 Carboxylesterase family Proteasom_PSMB PF10508.9 EAQ87426.1 - 0.061 11.8 0.0 0.078 11.5 0.0 1.1 1 0 0 1 1 1 0 Proteasome non-ATPase 26S subunit COesterase PF00135.28 EAQ87427.1 - 2.5e-81 274.1 0.0 4.3e-81 273.3 0.0 1.3 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EAQ87427.1 - 4.9e-05 23.3 0.1 0.00031 20.7 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Pectinesterase PF01095.19 EAQ87429.1 - 8.2e-42 142.9 1.5 1.2e-41 142.4 1.5 1.1 1 0 0 1 1 1 1 Pectinesterase AA_permease PF00324.21 EAQ87430.1 - 5.8e-127 424.2 42.4 7.2e-127 423.9 42.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EAQ87430.1 - 3.1e-32 112.0 46.8 3.7e-32 111.7 46.8 1.1 1 0 0 1 1 1 1 Amino acid permease Egh16-like PF11327.8 EAQ87433.1 - 1.4e-65 221.2 7.7 1.8e-65 220.8 7.7 1.1 1 0 0 1 1 1 1 Egh16-like virulence factor PBP PF01161.20 EAQ87434.1 - 2.1e-06 28.1 0.2 8.2e-06 26.2 0.1 2.0 2 0 0 2 2 2 1 Phosphatidylethanolamine-binding protein Het-C PF07217.11 EAQ87434.1 - 0.032 12.8 0.0 0.061 11.9 0.0 1.3 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C DUF390 PF04094.14 EAQ87434.1 - 0.58 8.4 3.4 0.97 7.6 3.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF390) AhpC-TSA PF00578.21 EAQ87435.1 - 1.5e-10 41.1 0.0 2.5e-10 40.3 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EAQ87435.1 - 5.3e-05 23.0 0.0 6.7e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 EAQ87435.1 - 0.00021 21.4 0.0 0.00031 20.8 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme Thioredoxin_8 PF13905.6 EAQ87435.1 - 0.057 13.8 0.0 0.44 10.9 0.0 2.0 1 1 0 1 1 1 0 Thioredoxin-like GP11 PF08677.10 EAQ87435.1 - 0.13 11.7 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 GP11 baseplate wedge protein SbcCD_C PF13558.6 EAQ87437.1 - 8.1e-05 22.8 0.0 0.00028 21.1 0.0 1.9 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit SMC_N PF02463.19 EAQ87437.1 - 0.045 13.2 0.1 0.073 12.5 0.1 1.4 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain DUF3630 PF12305.8 EAQ87437.1 - 0.23 11.5 1.9 4.8 7.3 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3630) Phage_HK97_TLTM PF06120.11 EAQ87437.1 - 0.62 9.2 13.3 0.76 8.9 3.5 2.3 2 0 0 2 2 2 0 Tail length tape measure protein HALZ PF02183.18 EAQ87437.1 - 6.6 7.0 12.1 10 6.4 1.2 3.5 3 0 0 3 3 3 0 Homeobox associated leucine zipper Golgin_A5 PF09787.9 EAQ87437.1 - 9 5.7 27.7 6.5 6.1 11.4 2.2 2 0 0 2 2 2 0 Golgin subfamily A member 5 CRAL_TRIO PF00650.20 EAQ87438.1 - 1.2e-22 80.3 0.0 1.8e-22 79.8 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EAQ87438.1 - 1.2e-10 41.4 0.0 2.7e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Coatomer_WDAD PF04053.14 EAQ87439.1 - 2.2e-172 574.1 0.0 3.2e-171 570.3 0.0 2.0 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.32 EAQ87439.1 - 1.3e-38 130.3 3.6 1e-06 29.3 0.0 8.6 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAQ87439.1 - 2.7e-08 34.0 0.1 5.5 7.4 0.0 5.9 3 3 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EAQ87439.1 - 5.7e-07 28.6 2.3 0.016 13.9 0.0 4.8 1 1 3 5 5 5 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.6 EAQ87439.1 - 0.0045 17.0 0.1 2.1 8.4 0.0 3.9 2 2 2 4 4 4 1 Ciliary BBSome complex subunit 2, middle region Ribosomal_60s PF00428.19 EAQ87439.1 - 0.007 16.9 13.6 0.019 15.6 13.6 1.7 1 0 0 1 1 1 1 60s Acidic ribosomal protein Peptidase_M4 PF01447.18 EAQ87439.1 - 0.047 14.2 0.1 0.12 12.8 0.1 1.7 1 0 0 1 1 1 0 Thermolysin metallopeptidase, catalytic domain MetallophosC PF16370.5 EAQ87439.1 - 0.077 13.2 0.2 0.38 11.0 0.0 2.1 1 1 0 2 2 2 0 C terminal of Calcineurin-like phosphoesterase NOA36 PF06524.12 EAQ87439.1 - 1.4 8.2 9.8 2.1 7.6 9.8 1.2 1 0 0 1 1 1 0 NOA36 protein RNA_pol_3_Rpc31 PF11705.8 EAQ87439.1 - 6.4 7.0 12.4 9.9 6.3 12.4 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Mannitol_dh_C PF08125.13 EAQ87440.1 - 2.4e-40 138.6 0.0 4e-40 137.9 0.0 1.3 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.23 EAQ87440.1 - 1.2e-19 71.0 0.6 3.1e-19 69.6 0.1 1.9 2 0 0 2 2 2 1 Mannitol dehydrogenase Rossmann domain UDPG_MGDP_dh_N PF03721.14 EAQ87440.1 - 0.0017 18.0 0.0 0.0039 16.8 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Sacchrp_dh_NADP PF03435.18 EAQ87440.1 - 0.052 13.8 0.1 0.38 11.0 0.0 2.3 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain DUF2293 PF10056.9 EAQ87440.1 - 0.26 11.5 1.1 0.77 10.0 0.5 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2293) Pkinase PF00069.25 EAQ87442.1 - 4.6e-09 36.0 0.0 6.5e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 EAQ87442.1 - 0.00036 20.5 2.5 0.0012 18.8 2.5 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 EAQ87442.1 - 0.00064 19.1 0.0 0.00094 18.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EAQ87442.1 - 0.049 13.0 0.0 0.08 12.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family p450 PF00067.22 EAQ87444.1 - 2.6e-39 135.3 0.0 5.3e-28 98.0 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 RMI1_C PF16099.5 EAQ87444.1 - 0.24 11.3 0.0 0.39 10.6 0.0 1.3 1 0 0 1 1 1 0 Recq-mediated genome instability protein 1, C-terminal OB-fold MFS_1 PF07690.16 EAQ87445.1 - 2e-23 82.9 45.0 7.8e-18 64.5 29.3 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily GHMP_kinases_C PF08544.13 EAQ87445.1 - 0.013 15.8 0.4 0.34 11.3 0.2 2.6 2 0 0 2 2 2 0 GHMP kinases C terminal DUF349 PF03993.12 EAQ87446.1 - 0.018 15.4 1.5 0.043 14.1 1.5 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF349) RLL PF10036.9 EAQ87446.1 - 0.072 12.9 0.6 0.13 12.1 0.6 1.3 1 1 0 1 1 1 0 RNA transcription, translation and transport factor protein F-112 PF09645.10 EAQ87446.1 - 0.079 13.1 0.6 0.14 12.2 0.6 1.3 1 0 0 1 1 1 0 F-112 protein Nucleoside_tran PF01733.18 EAQ87446.1 - 0.085 12.2 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Nucleoside transporter Abhydrolase_6 PF12697.7 EAQ87447.1 - 5.7e-08 33.6 0.1 7.7e-08 33.2 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EAQ87447.1 - 2.6e-07 30.1 0.0 2.6e-06 26.9 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 EAQ87447.1 - 2.9e-07 30.4 0.0 3.8e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 EAQ87447.1 - 4.2e-06 26.4 0.0 0.00071 19.1 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 EAQ87447.1 - 9.5e-05 22.2 0.0 0.00031 20.5 0.0 1.8 1 1 1 2 2 2 1 alpha/beta hydrolase fold DLH PF01738.18 EAQ87447.1 - 0.00014 21.5 0.0 0.00025 20.7 0.0 1.4 1 0 0 1 1 1 1 Dienelactone hydrolase family BAAT_C PF08840.11 EAQ87447.1 - 0.00038 20.5 0.0 0.00056 19.9 0.0 1.4 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal AXE1 PF05448.12 EAQ87447.1 - 0.00059 18.6 0.0 0.0075 15.0 0.0 2.1 1 1 1 2 2 2 1 Acetyl xylan esterase (AXE1) Abhydrolase_3 PF07859.13 EAQ87447.1 - 0.017 15.0 0.0 0.027 14.4 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF1593 PF07632.11 EAQ87447.1 - 0.063 12.7 0.0 0.096 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1593) DUF1100 PF06500.11 EAQ87447.1 - 0.086 11.6 0.0 0.21 10.4 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1100) ADH_zinc_N PF00107.26 EAQ87448.1 - 3.5e-09 36.7 0.1 6e-09 36.0 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EAQ87448.1 - 1e-05 25.4 2.1 2.9e-05 23.9 0.1 2.4 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ketoacyl-synt PF00109.26 EAQ87449.1 - 6e-75 252.1 0.0 1.2e-74 251.1 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.6 EAQ87449.1 - 2.3e-46 158.4 1.3 2.3e-46 158.4 1.3 1.8 2 0 0 2 2 2 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 EAQ87449.1 - 9.9e-41 140.3 0.3 1.8e-40 139.4 0.3 1.3 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 EAQ87449.1 - 2.3e-33 115.6 0.1 8e-27 94.3 0.0 2.6 1 1 1 2 2 2 2 KR domain Ketoacyl-synt_C PF02801.22 EAQ87449.1 - 1.6e-30 105.5 0.1 6.4e-30 103.6 0.0 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 EAQ87449.1 - 1.8e-15 57.5 0.0 4.8e-15 56.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 EAQ87449.1 - 1.2e-13 51.5 0.0 3.5e-13 50.0 0.0 1.9 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_11 PF08241.12 EAQ87449.1 - 6e-12 46.1 0.0 2e-11 44.4 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAQ87449.1 - 2.5e-11 44.2 0.1 1.7e-10 41.5 0.0 2.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAQ87449.1 - 1.4e-10 41.1 0.0 3.1e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EAQ87449.1 - 5.5e-09 36.1 0.0 1.2e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 EAQ87449.1 - 1.3e-05 24.8 0.0 3.1e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase PP-binding PF00550.25 EAQ87449.1 - 2.1e-05 24.8 0.0 9.3e-05 22.7 0.0 2.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.23 EAQ87449.1 - 0.00022 20.6 0.0 0.00045 19.7 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Ubie_methyltran PF01209.18 EAQ87449.1 - 0.00093 18.6 0.0 0.0018 17.7 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 EAQ87449.1 - 0.029 13.6 0.0 0.051 12.9 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain DUF3669 PF12417.8 EAQ87451.1 - 2.1e-07 31.0 0.1 6e-07 29.6 0.0 1.7 2 0 0 2 2 2 1 Zinc finger protein MULE PF10551.9 EAQ87453.1 - 1.2e-13 51.2 0.0 2.4e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 MULE transposase domain Helitron_like_N PF14214.6 EAQ87454.1 - 9.1e-27 94.5 2.2 5.4e-26 92.0 2.2 2.1 1 1 0 1 1 1 1 Helitron helicase-like domain at N-terminus KNOX2 PF03791.13 EAQ87455.1 - 0.12 11.8 0.1 0.27 10.8 0.1 1.5 1 0 0 1 1 1 0 KNOX2 domain Dimer_Tnp_hAT PF05699.14 EAQ87457.1 - 4e-13 49.0 0.2 2.8e-12 46.2 0.1 2.3 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region HRI1 PF16815.5 EAQ87458.1 - 1.2e-70 237.8 0.4 1.5e-70 237.5 0.4 1.0 1 0 0 1 1 1 1 Protein HRI1 TMEM154 PF15102.6 EAQ87460.1 - 0.0042 17.0 0.0 0.0073 16.2 0.0 1.3 1 0 0 1 1 1 1 TMEM154 protein family Granulin PF00396.18 EAQ87460.1 - 0.12 12.7 5.9 0.15 12.4 1.8 2.6 2 0 0 2 2 2 0 Granulin Mpv17_PMP22 PF04117.12 EAQ87461.1 - 2.9e-21 75.5 0.4 1e-20 73.7 0.1 2.1 2 0 0 2 2 2 1 Mpv17 / PMP22 family PGK PF00162.19 EAQ87462.1 - 1.4e-141 471.9 1.1 1.7e-141 471.6 1.1 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase DUF3530 PF12048.8 EAQ87462.1 - 0.042 13.3 0.0 0.058 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) FIVAR PF07554.13 EAQ87462.1 - 0.13 13.0 0.7 15 6.4 0.0 3.5 4 0 0 4 4 4 0 FIVAR domain DSS1_SEM1 PF05160.13 EAQ87463.1 - 3.4e-23 81.4 14.0 5.9e-23 80.7 14.0 1.4 1 0 0 1 1 1 1 DSS1/SEM1 family DUF3808 PF10300.9 EAQ87465.1 - 1.2e-130 436.4 0.0 1.7e-130 436.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_19 PF14559.6 EAQ87465.1 - 0.18 12.3 8.6 0.76 10.3 0.2 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 EAQ87465.1 - 2.1 8.3 4.7 7.9 6.5 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Abhydrolase_1 PF00561.20 EAQ87467.1 - 6e-09 35.9 0.0 2.8e-08 33.7 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EAQ87467.1 - 2.5e-05 23.7 0.0 0.003 16.9 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Methyltransf_25 PF13649.6 EAQ87468.1 - 6.1e-08 33.3 0.0 1.1e-07 32.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EAQ87468.1 - 4.3e-05 24.1 0.0 6.8e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAQ87468.1 - 9.9e-05 22.2 0.1 0.00016 21.5 0.0 1.4 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 EAQ87468.1 - 0.00016 21.3 0.0 0.00018 21.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 EAQ87468.1 - 0.00051 19.9 0.0 0.00053 19.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EAQ87468.1 - 0.00077 20.2 0.0 0.0013 19.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 EAQ87468.1 - 0.0014 18.1 0.0 0.0018 17.8 0.0 1.1 1 0 0 1 1 1 1 Tellurite resistance protein TehB tRNA_U5-meth_tr PF05958.11 EAQ87468.1 - 0.0062 15.6 0.0 0.0066 15.5 0.0 1.1 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase RrnaAD PF00398.20 EAQ87468.1 - 0.013 14.6 0.0 0.013 14.6 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase DREV PF05219.12 EAQ87468.1 - 0.016 14.3 0.0 0.016 14.3 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase PrmA PF06325.13 EAQ87468.1 - 0.017 14.6 0.0 0.017 14.6 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 EAQ87468.1 - 0.03 14.3 0.0 0.037 14.0 0.0 1.3 1 1 0 1 1 1 0 Methyltransferase domain NodS PF05401.11 EAQ87468.1 - 0.067 12.8 0.0 0.087 12.4 0.0 1.1 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_16 PF10294.9 EAQ87468.1 - 0.079 12.7 0.0 0.089 12.5 0.0 1.2 1 1 0 1 1 1 0 Lysine methyltransferase DUF2958 PF11171.8 EAQ87468.1 - 0.11 12.8 0.0 0.12 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2958) Mito_carr PF00153.27 EAQ87470.1 - 3e-24 84.8 9.4 1.6e-15 56.7 0.6 3.9 3 1 1 4 4 4 4 Mitochondrial carrier protein PrpF PF04303.13 EAQ87471.1 - 2.2e-58 198.0 0.0 3.9e-52 177.4 0.0 2.3 2 0 0 2 2 2 2 PrpF protein Fungal_trans PF04082.18 EAQ87471.1 - 6e-21 74.7 0.0 8.9e-21 74.1 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sugar_tr PF00083.24 EAQ87472.1 - 1.2e-119 400.2 23.7 1.3e-119 400.0 23.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EAQ87472.1 - 2.4e-26 92.5 77.1 4.6e-25 88.3 40.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Methyltransf_23 PF13489.6 EAQ87473.1 - 1.8e-08 34.4 0.0 4e-08 33.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAQ87473.1 - 0.0036 18.0 0.0 0.023 15.4 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain SCNM1_acidic PF15805.5 EAQ87473.1 - 0.015 15.0 0.3 0.047 13.4 0.1 2.0 2 0 0 2 2 2 0 Acidic C-terminal region of sodium channel modifier 1 SCNM1 Methyltransf_31 PF13847.6 EAQ87473.1 - 0.094 12.5 0.0 0.45 10.3 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Pox_E2-like PF04497.12 EAQ87474.1 - 0.12 10.8 0.0 0.14 10.5 0.0 1.1 1 0 0 1 1 1 0 Poxviridae protein Mobilization_B PF17511.2 EAQ87475.1 - 0.22 11.9 0.0 0.3 11.5 0.0 1.2 1 0 0 1 1 1 0 Mobilization protein B MFS_1 PF07690.16 EAQ87476.1 - 2.9e-12 46.2 14.1 2.9e-12 46.2 14.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.16 EAQ87476.1 - 0.00018 21.3 1.6 0.00048 19.9 1.6 1.7 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 DHO_dh PF01180.21 EAQ87478.1 - 1.4e-60 205.1 0.0 4.3e-60 203.4 0.0 1.7 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase PcrB PF01884.17 EAQ87478.1 - 0.47 9.9 2.5 6.4 6.2 0.0 2.5 3 0 0 3 3 3 0 PcrB family Glyco_hydro_61 PF03443.14 EAQ87479.1 - 5.9e-31 108.0 0.0 3.6e-30 105.4 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 61 DUF5624 PF18538.1 EAQ87479.1 - 0.12 12.4 0.0 0.19 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5624) FAD_binding_3 PF01494.19 EAQ87480.1 - 9.9e-08 31.6 0.0 4.2e-06 26.2 0.1 2.6 3 0 0 3 3 3 2 FAD binding domain COesterase PF00135.28 EAQ87481.1 - 2.2e-55 188.5 0.1 2.7e-55 188.2 0.1 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EAQ87481.1 - 2.5e-08 34.0 0.1 2.6e-07 30.7 0.0 2.5 2 1 0 2 2 2 1 alpha/beta hydrolase fold DZR PF12773.7 EAQ87483.1 - 5.3e-05 23.2 9.0 0.004 17.1 2.0 2.6 1 1 2 3 3 3 3 Double zinc ribbon OrfB_Zn_ribbon PF07282.11 EAQ87483.1 - 0.0074 16.2 11.2 0.23 11.4 0.2 3.6 2 2 2 4 4 4 2 Putative transposase DNA-binding domain zf-NADH-PPase PF09297.11 EAQ87483.1 - 0.048 13.3 2.2 0.048 13.3 2.2 4.4 3 3 2 5 5 5 0 NADH pyrophosphatase zinc ribbon domain zinc_ribbon_2 PF13240.6 EAQ87483.1 - 0.2 11.4 0.2 0.2 11.4 0.2 3.9 5 0 0 5 5 5 0 zinc-ribbon domain ADD_DNMT3 PF17980.1 EAQ87483.1 - 1 9.4 4.8 7.4 6.6 0.1 2.4 2 0 0 2 2 2 0 Cysteine rich ADD domain in DNMT3 DNA_RNApol_7kD PF03604.13 EAQ87483.1 - 2 8.1 6.0 1.2 8.9 0.1 2.6 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit DUF1272 PF06906.11 EAQ87483.1 - 7.2 6.8 10.2 1.3 9.2 0.8 3.2 3 1 1 4 4 4 0 Protein of unknown function (DUF1272) LysM PF01476.20 EAQ87484.1 - 1.5e-06 28.2 0.0 2.5e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 LysM domain DUF2457 PF10446.9 EAQ87484.1 - 3.7 6.6 5.3 4.6 6.3 5.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) p450 PF00067.22 EAQ87485.1 - 9.5e-60 202.6 0.0 1.3e-59 202.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Ribosomal_L1 PF00687.21 EAQ87486.1 - 3e-64 216.5 0.4 3e-64 216.5 0.4 1.5 2 0 0 2 2 2 1 Ribosomal protein L1p/L10e family Prok-E2_B PF14461.6 EAQ87486.1 - 0.1 12.3 0.0 3.8 7.2 0.0 2.4 2 0 0 2 2 2 0 Prokaryotic E2 family B DUF4124 PF13511.6 EAQ87486.1 - 0.54 10.6 4.9 0.65 10.4 0.2 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4124) IFP_35_N PF07334.13 EAQ87486.1 - 0.75 9.9 4.0 2.6 8.2 4.0 2.0 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Palm_thioest PF02089.15 EAQ87488.1 - 4.8e-54 183.7 0.0 3.4e-50 171.2 0.0 2.0 1 1 1 2 2 2 2 Palmitoyl protein thioesterase SF3A3 PF16837.5 EAQ87488.1 - 0.061 13.8 0.8 0.1 13.1 0.8 1.3 1 0 0 1 1 1 0 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 Lipase_2 PF01674.18 EAQ87488.1 - 0.17 11.4 0.1 0.28 10.7 0.0 1.4 2 0 0 2 2 2 0 Lipase (class 2) DUF3941 PF13081.6 EAQ87488.1 - 0.29 11.5 2.7 0.5 10.8 2.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3941) zf-MYND PF01753.18 EAQ87489.1 - 0.0011 19.0 9.9 0.0019 18.2 9.9 1.4 1 0 0 1 1 1 1 MYND finger adh_short PF00106.25 EAQ87490.1 - 5.4e-25 88.0 1.8 1.4e-22 80.1 0.2 2.1 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EAQ87490.1 - 2.7e-14 53.3 0.2 3.3e-14 53.0 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epiglycanin_C PF14654.6 EAQ87491.1 - 0.12 12.4 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region DUF4106 PF13388.6 EAQ87492.1 - 0.51 9.5 4.8 0.59 9.3 4.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) SelP_N PF04592.14 EAQ87492.1 - 1.1 8.6 6.9 1.4 8.3 6.9 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region RIX1 PF08167.12 EAQ87494.1 - 0.099 12.4 3.2 9.5 5.9 0.0 4.1 4 0 0 4 4 4 0 rRNA processing/ribosome biogenesis Glyco_hydro_79C PF16862.5 EAQ87495.1 - 5.5e-18 65.8 0.0 1.2e-17 64.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain RVT_1 PF00078.27 EAQ87496.1 - 3.2e-15 56.3 0.0 5.6e-15 55.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 EAQ87496.1 - 0.097 13.4 0.0 0.43 11.3 0.0 2.1 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase MMR_HSR1 PF01926.23 EAQ87497.1 - 1.2e-05 25.4 0.0 0.13 12.3 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AIG1 PF04548.16 EAQ87497.1 - 2.1e-05 23.9 0.0 0.044 13.1 0.0 2.4 2 0 0 2 2 2 2 AIG1 family RsgA_GTPase PF03193.16 EAQ87497.1 - 0.00041 20.3 0.0 0.0061 16.5 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 EAQ87497.1 - 0.0042 16.8 0.0 0.0092 15.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Septin PF00735.18 EAQ87497.1 - 0.0043 16.4 0.0 0.017 14.4 0.0 2.0 1 1 0 1 1 1 1 Septin ABC_tran PF00005.27 EAQ87497.1 - 0.031 14.8 0.1 0.38 11.3 0.0 2.5 2 0 0 2 2 2 0 ABC transporter AAA_16 PF13191.6 EAQ87497.1 - 0.036 14.4 0.0 0.12 12.7 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain Dynamin_N PF00350.23 EAQ87497.1 - 0.05 13.7 0.1 2.7 8.0 0.0 2.6 2 0 0 2 2 2 0 Dynamin family AAA_23 PF13476.6 EAQ87497.1 - 0.068 13.7 1.0 0.35 11.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain Swi5 PF07061.11 EAQ87497.1 - 0.084 13.0 0.0 0.31 11.1 0.0 2.0 1 0 0 1 1 1 0 Swi5 FtsK_SpoIIIE PF01580.18 EAQ87497.1 - 0.13 11.6 0.0 0.28 10.5 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family RVT_1 PF00078.27 EAQ87501.1 - 1.2e-38 132.8 0.0 1.2e-37 129.6 0.0 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) OTT_1508_deam PF14441.6 EAQ87503.1 - 2.1e-11 43.7 0.0 4.1e-11 42.7 0.0 1.5 1 0 0 1 1 1 1 OTT_1508-like deaminase MSA-2c PF12238.8 EAQ87503.1 - 0.0012 18.9 0.8 0.002 18.2 0.8 1.3 1 0 0 1 1 1 1 Merozoite surface antigen 2c ORC6 PF05460.13 EAQ87503.1 - 6.7 5.9 9.2 5.4 6.2 6.3 1.9 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) SNO PF01174.19 EAQ87504.1 - 2.4e-53 180.8 0.0 1.2e-52 178.5 0.0 1.8 1 1 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 EAQ87504.1 - 1.2e-10 41.3 0.0 6.5e-09 35.7 0.0 2.1 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_S51 PF03575.17 EAQ87504.1 - 7.5e-05 22.5 0.0 0.00013 21.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase family S51 GATase PF00117.28 EAQ87504.1 - 0.00096 19.0 0.2 0.027 14.2 0.2 2.1 1 1 0 1 1 1 1 Glutamine amidotransferase class-I DJ-1_PfpI PF01965.24 EAQ87504.1 - 0.0018 18.1 0.0 0.0035 17.2 0.0 1.5 1 0 0 1 1 1 1 DJ-1/PfpI family Sin_N PF04801.13 EAQ87506.1 - 7.8e-07 28.7 0.0 1.2e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Sin-like protein conserved region Replicase PF03090.17 EAQ87506.1 - 0.049 13.5 0.0 0.091 12.6 0.0 1.3 1 0 0 1 1 1 0 Replicase family PAT1 PF09770.9 EAQ87508.1 - 1.3e-300 999.7 28.2 2.1e-162 542.4 20.9 2.0 2 0 0 2 2 2 2 Topoisomerase II-associated protein PAT1 Glyco_transf_15 PF01793.16 EAQ87509.1 - 1.4e-130 435.3 8.1 1.8e-130 435.0 8.1 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Ribosom_S12_S23 PF00164.25 EAQ87510.1 - 2.6e-25 88.3 0.1 3.2e-25 88.0 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Acyl-CoA_dh_1 PF00441.24 EAQ87511.1 - 1.3e-40 139.0 4.5 2.2e-40 138.3 4.5 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EAQ87511.1 - 4.7e-29 101.3 0.3 1.1e-28 100.1 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EAQ87511.1 - 3.1e-23 81.8 0.0 6.6e-23 80.7 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EAQ87511.1 - 2.4e-17 63.4 0.5 4e-17 62.8 0.5 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 EAQ87511.1 - 0.00013 21.8 0.0 0.00035 20.3 0.0 1.7 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal AgrD PF05931.11 EAQ87511.1 - 0.0079 16.2 0.0 0.019 15.0 0.0 1.6 1 0 0 1 1 1 1 Staphylococcal AgrD protein CCT PF06203.14 EAQ87511.1 - 0.22 11.6 0.4 0.41 10.7 0.4 1.4 1 0 0 1 1 1 0 CCT motif Pkinase PF00069.25 EAQ87512.1 - 5.2e-59 199.8 0.0 1.1e-58 198.7 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ87512.1 - 3.6e-35 121.5 0.0 6.8e-35 120.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.16 EAQ87512.1 - 1e-22 80.0 19.9 6.5e-12 45.4 4.6 2.8 2 0 0 2 2 2 2 Hr1 repeat C1_1 PF00130.22 EAQ87512.1 - 1.1e-20 73.2 26.5 1.4e-12 47.3 9.7 2.3 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.24 EAQ87512.1 - 3e-14 53.5 1.0 1.1e-13 51.6 1.0 2.1 1 0 0 1 1 1 1 Protein kinase C terminal domain C2 PF00168.30 EAQ87512.1 - 1.2e-05 25.6 0.0 2.1e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 C2 domain Kinase-like PF14531.6 EAQ87512.1 - 0.026 13.8 0.0 0.048 13.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like PAT1 PF09770.9 EAQ87512.1 - 3.9 5.6 11.7 7.5 4.7 11.7 1.4 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.13 EAQ87512.1 - 5.8 6.8 27.7 15 5.4 27.7 1.7 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit She9_MDM33 PF05546.11 EAQ87513.1 - 9.7e-19 68.0 2.0 1.6e-12 47.6 0.5 2.2 2 0 0 2 2 2 2 She9 / Mdm33 family HAD PF12710.7 EAQ87515.1 - 1.2e-24 87.8 0.0 1.5e-24 87.5 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 EAQ87515.1 - 0.00029 20.3 0.0 0.0074 15.7 0.0 2.1 2 0 0 2 2 2 1 Putative Phosphatase UMPH-1 PF05822.12 EAQ87515.1 - 0.0018 17.8 0.0 0.0025 17.3 0.0 1.5 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) Hydrolase PF00702.26 EAQ87515.1 - 0.0077 16.5 0.3 1.8 8.8 0.0 3.0 2 1 0 3 3 3 1 haloacid dehalogenase-like hydrolase eIF-1a PF01176.19 EAQ87516.1 - 1.7e-18 66.2 0.0 2.4e-18 65.7 0.0 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 DUF4731 PF15875.5 EAQ87517.1 - 0.25 11.5 0.4 0.51 10.6 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4731) DAO PF01266.24 EAQ87518.1 - 5e-28 98.7 1.9 6.1e-28 98.4 1.9 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase PIF1 PF05970.14 EAQ87519.1 - 4.5e-05 22.8 0.0 5.5e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase UvrD_C_2 PF13538.6 EAQ87519.1 - 0.0019 18.0 0.0 0.0044 16.8 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.14 EAQ87519.1 - 0.0054 14.7 0.0 0.0075 14.2 0.0 1.1 1 0 0 1 1 1 1 Helicase PIF1 PF05970.14 EAQ87520.1 - 0.062 12.5 0.2 0.1 11.7 0.2 1.3 1 0 0 1 1 1 0 PIF1-like helicase Thioredoxin PF00085.20 EAQ87521.1 - 4e-20 71.7 0.0 6.5e-20 71.0 0.0 1.3 1 1 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 EAQ87521.1 - 9.5e-05 21.9 0.0 0.00011 21.7 0.0 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 EAQ87521.1 - 0.00083 19.8 0.1 0.0023 18.3 0.1 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain HyaE PF07449.11 EAQ87521.1 - 0.044 13.7 0.0 0.065 13.2 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE WSC PF01822.19 EAQ87522.1 - 2.1e-22 79.1 8.1 3.9e-22 78.2 8.1 1.4 1 0 0 1 1 1 1 WSC domain Staphostatin_B PF09023.10 EAQ87522.1 - 0.17 12.0 0.0 0.33 11.0 0.0 1.4 1 0 0 1 1 1 0 Staphostatin B zf-C2HE PF16278.5 EAQ87523.1 - 8.4e-19 67.8 0.0 2e-18 66.6 0.0 1.7 1 0 0 1 1 1 1 C2HE / C2H2 / C2HC zinc-binding finger DcpS_C PF11969.8 EAQ87523.1 - 1.1e-12 48.4 5.6 1.4e-11 44.9 5.6 2.1 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 EAQ87523.1 - 1.4e-12 48.1 0.1 2.7e-12 47.3 0.1 1.4 1 0 0 1 1 1 1 HIT domain NACHT PF05729.12 EAQ87525.1 - 0.00011 22.1 0.0 0.00026 21.0 0.0 1.5 1 0 0 1 1 1 1 NACHT domain Mannosyl_trans3 PF11051.8 EAQ87526.1 - 1.4e-24 86.9 1.6 1e-13 51.3 0.2 2.2 1 1 1 2 2 2 2 Mannosyltransferase putative Nuf2 PF03800.14 EAQ87529.1 - 4.5e-42 143.5 0.0 1.6e-41 141.6 0.0 2.0 1 0 0 1 1 1 1 Nuf2 family DHR10 PF18595.1 EAQ87529.1 - 2e-37 127.8 15.9 2e-37 127.8 15.9 4.4 4 1 1 5 5 5 1 Designed helical repeat protein 10 domain Prefoldin_2 PF01920.20 EAQ87529.1 - 0.052 13.5 0.9 0.052 13.5 0.9 5.8 2 1 3 6 6 6 0 Prefoldin subunit DUF1664 PF07889.12 EAQ87529.1 - 4.9 7.2 18.6 7.8 6.6 2.3 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Bacillus_HBL PF05791.11 EAQ87529.1 - 7.6 6.3 15.9 1.9 8.3 2.1 3.7 2 1 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Adaptin_N PF01602.20 EAQ87530.1 - 2.6e-87 293.6 0.7 1.9e-85 287.4 0.5 2.0 2 0 0 2 2 2 2 Adaptin N terminal region Cnd1 PF12717.7 EAQ87530.1 - 1.3e-14 54.6 0.2 3e-13 50.1 0.0 2.9 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EAQ87530.1 - 3e-10 40.3 1.2 1.7e-05 25.2 0.0 4.1 3 1 0 3 3 3 2 HEAT repeats HEAT PF02985.22 EAQ87530.1 - 1.1e-07 31.4 2.7 0.041 14.2 0.0 5.2 6 0 0 6 6 5 2 HEAT repeat HEAT_EZ PF13513.6 EAQ87530.1 - 8.4e-05 23.0 2.1 0.074 13.6 0.0 4.2 4 0 0 4 4 4 1 HEAT-like repeat Cohesin_HEAT PF12765.7 EAQ87530.1 - 0.029 14.7 0.5 0.22 11.8 0.0 2.7 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion Nop14 PF04147.12 EAQ87530.1 - 0.029 12.6 18.3 0.045 12.0 18.3 1.2 1 0 0 1 1 1 0 Nop14-like family RTP1_C1 PF10363.9 EAQ87530.1 - 0.11 12.6 0.0 3.5 7.8 0.0 2.7 2 1 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 RNA_pol_3_Rpc31 PF11705.8 EAQ87530.1 - 0.2 11.9 19.0 0.33 11.2 19.0 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 RR_TM4-6 PF06459.12 EAQ87530.1 - 0.2 11.4 9.9 0.35 10.7 9.9 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SDA1 PF05285.12 EAQ87530.1 - 0.35 10.2 26.3 0.62 9.4 26.3 1.3 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 EAQ87530.1 - 1.7 7.9 17.3 3.1 7.1 17.3 1.4 1 0 0 1 1 1 0 BUD22 DUF913 PF06025.12 EAQ87530.1 - 1.9 7.4 6.6 14 4.5 6.0 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) Presenilin PF01080.17 EAQ87530.1 - 2.3 6.9 5.1 3.8 6.2 5.1 1.3 1 0 0 1 1 1 0 Presenilin CPSF100_C PF13299.6 EAQ87530.1 - 3.9 7.6 7.8 10 6.3 7.8 1.7 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal NACHT PF05729.12 EAQ87531.1 - 1.7e-11 44.3 0.0 3.9e-11 43.1 0.0 1.5 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EAQ87531.1 - 9.1e-06 26.2 0.0 1.5e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain KAP_NTPase PF07693.14 EAQ87531.1 - 0.0024 17.1 0.0 1.5 8.0 0.0 2.1 1 1 1 2 2 2 2 KAP family P-loop domain AAA_29 PF13555.6 EAQ87531.1 - 0.0042 16.8 0.1 0.0084 15.8 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_30 PF13604.6 EAQ87531.1 - 0.011 15.5 0.0 0.021 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EAQ87531.1 - 0.031 14.5 0.0 0.062 13.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EAQ87531.1 - 0.031 14.8 0.0 0.05 14.1 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_18 PF13238.6 EAQ87531.1 - 0.068 13.7 0.1 0.14 12.7 0.1 1.8 1 1 0 1 1 1 0 AAA domain APS_kinase PF01583.20 EAQ87531.1 - 0.089 12.7 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase NB-ARC PF00931.22 EAQ87531.1 - 0.14 11.3 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain Ank_2 PF12796.7 EAQ87533.1 - 1.2e-22 80.3 0.0 3.8e-10 40.2 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAQ87533.1 - 1.9e-18 64.6 0.2 0.0031 17.9 0.0 5.2 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 EAQ87533.1 - 7e-17 61.6 0.1 8.3e-07 29.4 0.0 3.7 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAQ87533.1 - 5.7e-11 42.4 3.1 0.0029 17.9 0.2 5.0 1 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 EAQ87533.1 - 1.7e-10 40.8 7.4 0.15 12.5 0.1 4.8 5 0 0 5 5 5 4 Ankyrin repeat FA PF08736.11 EAQ87533.1 - 0.029 14.5 0.3 7.8 6.7 0.0 2.9 3 0 0 3 3 3 0 FERM adjacent (FA) SH3_9 PF14604.6 EAQ87534.1 - 5.3e-06 26.2 0.0 1.1e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EAQ87534.1 - 0.0001 21.8 0.0 0.00019 21.0 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EAQ87534.1 - 0.0053 16.4 0.0 0.013 15.2 0.0 1.6 2 0 0 2 2 2 1 Variant SH3 domain zf-C2H2_4 PF13894.6 EAQ87534.1 - 6.4 7.9 8.8 84 4.4 0.1 4.2 4 0 0 4 4 4 0 C2H2-type zinc finger SapA PF02199.15 EAQ87538.1 - 0.0064 16.8 1.5 0.014 15.7 1.5 1.5 1 0 0 1 1 1 1 Saposin A-type domain Metallophos PF00149.28 EAQ87539.1 - 9.9e-30 104.6 0.1 1.2e-29 104.2 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EAQ87539.1 - 0.04 14.4 0.5 0.098 13.1 0.5 1.7 1 1 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 EAQ87539.1 - 0.16 12.1 0.0 0.31 11.2 0.0 1.5 2 0 0 2 2 2 0 Calcineurin-like phosphoesterase superfamily domain Rho_GDI PF02115.17 EAQ87540.1 - 7.3e-57 192.3 0.4 8.9e-56 188.7 0.1 2.0 2 0 0 2 2 2 2 RHO protein GDP dissociation inhibitor tRNA_int_end_N2 PF12928.7 EAQ87541.1 - 0.16 12.1 0.0 0.3 11.3 0.0 1.4 1 0 0 1 1 1 0 tRNA-splicing endonuclease subunit sen54 N-term NAD_binding_2 PF03446.15 EAQ87542.1 - 7.2e-36 123.7 0.0 1.1e-35 123.1 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 EAQ87542.1 - 4.9e-30 104.3 0.3 1.1e-29 103.1 0.0 1.7 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 EAQ87542.1 - 2.1e-06 28.2 0.0 5.7e-06 26.8 0.0 1.8 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent OCD_Mu_crystall PF02423.15 EAQ87542.1 - 4.2e-06 25.9 0.0 6.1e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family GFO_IDH_MocA PF01408.22 EAQ87542.1 - 0.00033 21.5 0.0 0.00078 20.3 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold TrkA_N PF02254.18 EAQ87542.1 - 0.0043 17.3 0.0 0.0079 16.4 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain Semialdhyde_dh PF01118.24 EAQ87542.1 - 0.015 15.7 0.0 0.038 14.4 0.0 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 EAQ87542.1 - 0.12 12.3 0.1 0.76 9.6 0.1 2.1 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RTA1 PF04479.13 EAQ87543.1 - 6.2e-65 218.7 2.2 9.3e-65 218.1 2.2 1.3 1 0 0 1 1 1 1 RTA1 like protein RhoGEF PF00621.20 EAQ87545.1 - 1.1e-26 94.2 0.6 8.6e-26 91.3 0.0 2.3 2 0 0 2 2 2 1 RhoGEF domain DUF3507 PF12015.8 EAQ87545.1 - 0.017 14.8 0.0 0.034 13.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3507) Nod1 PF17114.5 EAQ87545.1 - 0.038 14.1 0.0 0.19 11.9 0.0 2.3 1 0 0 1 1 1 0 Gef2-related medial cortical node protein Nod1 ApoLp-III PF07464.11 EAQ87545.1 - 0.14 12.3 11.5 0.023 14.8 3.7 2.9 2 1 1 3 3 3 0 Apolipophorin-III precursor (apoLp-III) Mce4_CUP1 PF11887.8 EAQ87545.1 - 0.24 10.8 1.3 0.8 9.1 0.3 2.2 2 0 0 2 2 2 0 Cholesterol uptake porter CUP1 of Mce4, putative DUF3584 PF12128.8 EAQ87545.1 - 0.49 7.8 11.3 0.85 7.1 11.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Seryl_tRNA_N PF02403.22 EAQ87545.1 - 1.7 8.9 14.8 0.83 9.9 7.2 3.3 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain CdvA PF18822.1 EAQ87545.1 - 3 7.7 14.5 1.7 8.5 5.4 3.3 2 1 1 3 3 3 0 CdvA-like coiled-coil domain PMC2NT PF08066.12 EAQ87545.1 - 6.5 7.5 6.3 8.1 7.2 0.1 3.8 3 1 0 3 3 3 0 PMC2NT (NUC016) domain Xpo1 PF08389.12 EAQ87546.1 - 0.007 16.4 0.0 0.02 15.0 0.0 1.9 1 1 0 1 1 1 1 Exportin 1-like protein GRIP PF01465.20 EAQ87546.1 - 0.15 12.0 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 GRIP domain PI31_Prot_N PF11566.8 EAQ87547.1 - 4.1e-34 117.7 0.0 6.9e-34 117.0 0.0 1.3 1 1 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.11 EAQ87547.1 - 4.3e-15 56.7 23.5 4.3e-15 56.7 23.5 3.9 4 2 0 4 4 4 1 PI31 proteasome regulator ActA PF05058.12 EAQ87547.1 - 5.1 5.3 7.2 6.9 4.9 7.2 1.1 1 0 0 1 1 1 0 ActA Protein Dcc1 PF09724.9 EAQ87549.1 - 3.7e-11 42.9 0.0 4.5e-11 42.6 0.0 1.1 1 0 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 IBR PF01485.21 EAQ87550.1 - 0.0013 18.9 29.3 0.003 17.7 7.1 3.6 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain BHD_3 PF10405.9 EAQ87551.1 - 2.2e-26 92.1 0.1 5e-26 90.9 0.1 1.7 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 EAQ87551.1 - 4.3e-19 68.1 0.2 7.9e-19 67.2 0.2 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 EAQ87551.1 - 4.1e-17 62.9 0.6 4.1e-17 62.9 0.6 6.7 8 2 0 8 8 8 1 Rad4 beta-hairpin domain 2 Rad4 PF03835.15 EAQ87551.1 - 4.8e-12 45.8 0.1 1.4e-08 34.5 0.0 2.9 1 1 1 2 2 2 2 Rad4 transglutaminase-like domain Transglut_core PF01841.19 EAQ87551.1 - 0.012 16.1 0.0 0.031 14.7 0.0 1.8 1 1 0 1 1 1 0 Transglutaminase-like superfamily zf-AN1 PF01428.16 EAQ87552.1 - 1e-24 86.4 22.2 4.4e-13 49.2 8.5 2.2 2 0 0 2 2 2 2 AN1-like Zinc finger IBR PF01485.21 EAQ87552.1 - 0.08 13.2 17.1 0.18 12.0 1.7 2.7 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain Transp_Tc5_C PF04236.15 EAQ87552.1 - 0.35 11.3 15.5 1 9.7 6.4 2.3 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain C1_4 PF07975.12 EAQ87552.1 - 3.2 8.0 15.3 13 6.1 7.3 3.1 2 1 0 2 2 2 0 TFIIH C1-like domain MTP18 PF10558.9 EAQ87553.1 - 8.7e-50 169.0 0.1 1.3e-49 168.4 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) ATP19 PF11022.8 EAQ87554.1 - 4.7e-23 81.3 0.1 5.7e-23 81.1 0.1 1.0 1 0 0 1 1 1 1 ATP synthase subunit K PsbJ PF01788.17 EAQ87554.1 - 0.44 10.5 3.8 0.74 9.7 3.7 1.4 1 1 0 1 1 1 0 PsbJ Vps36_ESCRT-II PF11605.8 EAQ87558.1 - 1.9e-23 82.4 0.0 3.1e-23 81.8 0.0 1.3 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 Vps36-NZF-N PF16988.5 EAQ87558.1 - 2.7e-23 81.1 2.8 2.7e-23 81.1 2.8 2.8 2 1 0 2 2 2 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-Sec23_Sec24 PF04810.15 EAQ87558.1 - 0.00028 20.9 4.5 0.0087 16.1 0.2 2.7 2 0 0 2 2 2 2 Sec23/Sec24 zinc finger zf-RanBP PF00641.18 EAQ87558.1 - 0.0019 17.4 11.4 0.0086 15.4 0.5 2.8 3 0 0 3 3 3 2 Zn-finger in Ran binding protein and others GRAM PF02893.20 EAQ87558.1 - 0.0033 17.3 0.0 0.0053 16.6 0.0 1.3 1 0 0 1 1 1 1 GRAM domain DZR PF12773.7 EAQ87558.1 - 0.26 11.3 5.4 0.17 11.9 0.4 2.6 2 1 0 2 2 2 0 Double zinc ribbon DUF35_N PF12172.8 EAQ87558.1 - 1.4 8.8 6.3 0.14 12.0 1.0 2.0 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) PHD PF00628.29 EAQ87558.1 - 5.5 7.0 6.5 40 4.2 0.1 3.6 3 1 1 4 4 4 0 PHD-finger SAC3_GANP PF03399.16 EAQ87559.1 - 5e-26 91.8 6.0 7.4e-24 84.6 6.0 2.1 1 1 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 EAQ87559.1 - 0.017 15.1 0.3 0.041 13.9 0.0 1.7 2 0 0 2 2 2 0 CSN8/PSMD8/EIF3K family SH3_1 PF00018.28 EAQ87560.1 - 2e-25 88.1 0.0 1.3e-11 43.9 0.0 2.6 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 EAQ87560.1 - 1.7e-15 56.6 0.2 7.2e-08 32.2 0.0 3.0 3 0 0 3 3 3 2 Variant SH3 domain PX PF00787.24 EAQ87560.1 - 5e-15 55.5 0.0 9.4e-15 54.6 0.0 1.4 1 0 0 1 1 1 1 PX domain SH3_2 PF07653.17 EAQ87560.1 - 3e-11 42.8 0.0 2.7e-08 33.4 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain PB1 PF00564.24 EAQ87560.1 - 3.3e-08 33.4 0.0 5.7e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 PB1 domain TFIIA PF03153.13 EAQ87560.1 - 0.53 10.2 14.9 0.32 11.0 1.6 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit HTH_ABP1_N PF18107.1 EAQ87561.1 - 6.2e-25 86.7 2.7 1.8e-24 85.2 2.7 1.8 1 0 0 1 1 1 1 Fission yeast centromere protein N-terminal domain HTH_Tnp_Tc5 PF03221.16 EAQ87561.1 - 3.2e-18 65.5 2.5 3.1e-17 62.3 0.3 3.0 2 1 1 3 3 3 1 Tc5 transposase DNA-binding domain DUF3716 PF12511.8 EAQ87562.1 - 1.2e-33 114.9 13.7 1.3e-16 60.4 1.6 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3716) CoA_binding_2 PF13380.6 EAQ87564.1 - 2e-27 96.0 0.0 2.3e-27 95.8 0.0 1.1 1 0 0 1 1 1 1 CoA binding domain CoA_binding PF02629.19 EAQ87564.1 - 0.0021 18.7 0.0 0.0032 18.1 0.0 1.3 1 0 0 1 1 1 1 CoA binding domain DUF1425 PF07233.12 EAQ87564.1 - 0.18 11.7 0.0 0.25 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1425) EF-hand_9 PF14658.6 EAQ87565.1 - 5.5e-13 49.0 0.0 1.6e-06 28.3 0.0 2.5 2 1 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 EAQ87565.1 - 1.1e-11 45.0 0.3 3.8e-08 33.7 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 EAQ87565.1 - 4.3e-09 36.1 0.2 1.5e-05 24.8 0.1 3.2 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 EAQ87565.1 - 1.4e-07 30.8 0.8 0.016 15.1 0.1 3.8 4 1 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 EAQ87565.1 - 2e-07 30.1 0.9 0.023 14.2 0.0 3.9 4 1 0 4 4 4 3 EF hand FGAR-AT_linker PF18072.1 EAQ87565.1 - 0.19 12.3 0.0 5.1 7.7 0.1 2.2 2 0 0 2 2 2 0 Formylglycinamide ribonucleotide amidotransferase linker domain Peptidase_M3 PF01432.20 EAQ87566.1 - 5.7e-158 526.9 0.0 7.2e-158 526.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M91 PF14891.6 EAQ87566.1 - 0.04 14.2 0.0 0.09 13.1 0.0 1.5 1 0 0 1 1 1 0 Effector protein Aa_trans PF01490.18 EAQ87567.1 - 7.1e-62 209.4 37.7 8.1e-62 209.2 37.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF3742 PF12553.8 EAQ87567.1 - 0.0053 16.9 0.6 0.0053 16.9 0.6 2.6 2 1 1 3 3 3 1 Protein of unknown function (DUF3742) YGGT PF02325.17 EAQ87567.1 - 0.4 11.2 6.0 0.32 11.5 3.3 2.4 2 0 0 2 2 2 0 YGGT family DUF3464 PF11947.8 EAQ87567.1 - 0.42 10.4 1.4 1.5 8.6 1.4 1.9 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 BIR PF00653.21 EAQ87568.1 - 2.5e-35 120.9 5.1 4.5e-19 68.9 0.7 2.7 2 1 0 2 2 2 2 Inhibitor of Apoptosis domain DUF1996 PF09362.10 EAQ87569.1 - 8.3e-22 78.3 0.0 1.5e-21 77.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Pmp3 PF01679.17 EAQ87569.1 - 1.4e-14 54.0 0.7 2.5e-14 53.2 0.7 1.4 1 0 0 1 1 1 1 Proteolipid membrane potential modulator DUF5501 PF17605.2 EAQ87569.1 - 0.064 13.7 2.7 0.11 13.0 2.0 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5501) TALPID3 PF15324.6 EAQ87569.1 - 2.8 5.5 10.4 3.5 5.2 10.4 1.0 1 0 0 1 1 1 0 Hedgehog signalling target TipE PF16972.5 EAQ87569.1 - 7.1 5.7 7.6 9.6 5.3 7.6 1.1 1 0 0 1 1 1 0 Na+ channel auxiliary subunit TipE Tam41_Mmp37 PF09139.11 EAQ87570.1 - 3.5e-125 417.8 0.0 4.6e-125 417.3 0.0 1.1 1 0 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial MAD PF05557.13 EAQ87571.1 - 7.5e-61 206.3 57.0 9.7e-61 206.0 19.6 2.0 1 1 1 2 2 2 2 Mitotic checkpoint protein BRE1 PF08647.11 EAQ87571.1 - 0.0055 16.7 7.8 0.0055 16.7 7.8 7.1 3 1 4 7 7 7 1 BRE1 E3 ubiquitin ligase Abi_C PF14355.6 EAQ87571.1 - 0.11 12.7 3.2 0.3 11.2 0.1 3.1 2 0 0 2 2 2 0 Abortive infection C-terminus TssO PF17561.2 EAQ87571.1 - 5.2 7.2 18.9 19 5.4 0.1 3.9 3 1 0 3 3 3 0 Type VI secretion system, TssO muHD PF10291.9 EAQ87572.1 - 5.3e-84 281.8 0.0 7.9e-84 281.2 0.0 1.3 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.23 EAQ87572.1 - 6.1e-07 29.6 0.6 1.8e-06 28.1 0.0 2.2 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Mtr2 PF10429.9 EAQ87572.1 - 0.2 11.6 0.6 0.91 9.4 0.1 2.1 2 0 0 2 2 2 0 Nuclear pore RNA shuttling protein Mtr2 BPL_N PF09825.9 EAQ87572.1 - 0.22 10.6 0.8 0.45 9.6 0.8 1.4 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal DUF3340 PF11818.8 EAQ87572.1 - 0.7 10.0 8.4 1.7 8.8 7.4 2.2 1 1 1 2 2 2 0 C-terminal domain of tail specific protease (DUF3340) Pkinase PF00069.25 EAQ87573.1 - 1.9e-12 47.2 0.0 1.3e-08 34.5 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain GATase PF00117.28 EAQ87574.1 - 3.8e-27 95.3 0.0 9e-27 94.1 0.0 1.6 1 1 0 1 1 1 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.22 EAQ87574.1 - 2.2e-10 40.4 0.1 8.5e-10 38.6 0.0 2.0 2 0 0 2 2 2 1 GMP synthase C terminal domain NAD_synthase PF02540.17 EAQ87574.1 - 4.7e-07 29.2 0.1 1.8e-06 27.2 0.1 1.8 2 0 0 2 2 2 1 NAD synthase ThiI PF02568.14 EAQ87574.1 - 0.00058 19.5 0.0 0.00089 18.9 0.0 1.2 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) tRNA_Me_trans PF03054.16 EAQ87574.1 - 0.0006 18.7 0.1 0.00089 18.1 0.1 1.2 1 0 0 1 1 1 1 tRNA methyl transferase Peptidase_C26 PF07722.13 EAQ87574.1 - 0.0075 16.0 0.0 0.015 15.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 Arginosuc_synth PF00764.19 EAQ87574.1 - 0.033 13.5 0.1 0.047 13.0 0.1 1.2 1 0 0 1 1 1 0 Arginosuccinate synthase ATP_bind_3 PF01171.20 EAQ87574.1 - 0.047 13.4 0.0 0.073 12.8 0.0 1.3 1 0 0 1 1 1 0 PP-loop family DUF2501 PF10696.9 EAQ87574.1 - 0.093 13.0 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2501) QueC PF06508.13 EAQ87574.1 - 0.097 12.2 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC PAPS_reduct PF01507.19 EAQ87574.1 - 0.12 12.4 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family Fungal_trans_2 PF11951.8 EAQ87575.1 - 1.6e-18 66.7 0.2 2.3e-18 66.2 0.2 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EAQ87575.1 - 3.3e-08 33.5 8.3 6.9e-08 32.5 8.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amidoligase_2 PF12224.8 EAQ87576.1 - 6.6e-07 29.2 0.0 2.5e-06 27.4 0.0 1.8 2 0 0 2 2 2 1 Putative amidoligase enzyme WD40 PF00400.32 EAQ87577.1 - 1.5e-25 88.9 2.1 6e-09 36.4 0.1 3.9 3 0 0 3 3 3 3 WD domain, G-beta repeat NACHT PF05729.12 EAQ87577.1 - 1.1e-12 48.1 0.2 2.1e-12 47.3 0.2 1.4 1 0 0 1 1 1 1 NACHT domain NACHT_N PF17100.5 EAQ87577.1 - 6.1e-11 42.6 0.0 9.9e-11 41.9 0.0 1.3 1 0 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase ANAPC4_WD40 PF12894.7 EAQ87577.1 - 6.3e-09 36.0 0.0 0.0046 17.2 0.0 3.3 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EAQ87577.1 - 2.9e-07 29.8 0.5 0.017 14.1 0.0 3.1 1 1 2 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EAQ87577.1 - 0.0004 19.2 0.9 0.12 10.9 0.1 2.2 1 1 1 2 2 2 2 Nucleoporin Nup120/160 PD40 PF07676.12 EAQ87577.1 - 0.00041 20.2 1.0 8.9 6.4 0.1 3.5 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat AAA_16 PF13191.6 EAQ87577.1 - 0.00095 19.6 0.1 0.002 18.5 0.1 1.5 1 0 0 1 1 1 1 AAA ATPase domain Proteasome_A_N PF10584.9 EAQ87577.1 - 0.0012 18.5 0.1 7.8 6.3 0.0 3.6 3 0 0 3 3 3 1 Proteasome subunit A N-terminal signature ResIII PF04851.15 EAQ87577.1 - 0.043 13.8 0.0 0.097 12.7 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TsaE PF02367.17 EAQ87577.1 - 0.048 13.7 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_11 PF13086.6 EAQ87577.1 - 0.2 11.4 0.0 0.42 10.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Mito_fiss_reg PF05308.11 EAQ87579.1 - 4.2 7.4 9.7 6.7 6.7 9.7 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator PQ-loop PF04193.14 EAQ87580.1 - 1.5e-23 82.3 14.3 7.5e-13 48.0 0.8 3.0 3 0 0 3 3 3 2 PQ loop repeat DUF1345 PF07077.11 EAQ87580.1 - 0.0062 16.3 3.0 0.12 12.1 1.8 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF1345) DUF1129 PF06570.11 EAQ87580.1 - 0.26 10.8 1.7 0.44 10.0 0.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) Pox_A14 PF05767.12 EAQ87580.1 - 0.48 10.6 0.0 0.48 10.6 0.0 2.2 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 MASE5 PF17178.4 EAQ87580.1 - 1.4 8.7 8.7 0.66 9.8 6.0 1.8 2 0 0 2 2 2 0 Membrane-associated sensor R3H-assoc PF13902.6 EAQ87581.1 - 4.4e-26 91.8 2.1 4.4e-26 91.8 2.1 1.8 2 0 0 2 2 2 1 R3H-associated N-terminal domain R3H PF01424.22 EAQ87581.1 - 0.071 13.1 0.0 0.19 11.7 0.0 1.7 1 0 0 1 1 1 0 R3H domain DUF2277 PF10041.9 EAQ87582.1 - 0.6 10.5 3.4 4.8 7.6 0.0 3.6 4 0 0 4 4 4 0 Uncharacterized conserved protein (DUF2277) Rieske PF00355.26 EAQ87583.1 - 4.4e-11 42.6 0.0 7e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.14 EAQ87583.1 - 0.0022 18.5 0.2 0.0091 16.5 0.2 2.0 1 1 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region MMS1_N PF10433.9 EAQ87584.1 - 9.5e-127 423.6 0.0 1.3e-126 423.2 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 EAQ87584.1 - 4.6e-54 183.9 0.0 2.1e-51 175.2 0.0 3.4 2 2 1 3 3 3 2 CPSF A subunit region HTH_31 PF13560.6 EAQ87585.1 - 0.0069 16.7 4.9 0.084 13.2 1.2 2.2 2 0 0 2 2 2 2 Helix-turn-helix domain zf-trcl PF13451.6 EAQ87585.1 - 0.13 12.2 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Probable zinc-ribbon domain DJ-1_PfpI PF01965.24 EAQ87586.1 - 5.8e-18 65.2 0.0 4e-17 62.5 0.0 2.2 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 EAQ87586.1 - 1.1e-09 38.3 0.0 1.3e-08 34.8 0.0 2.0 1 1 0 1 1 1 1 ThiJ/PfpI family-like Podoplanin PF05808.11 EAQ87587.1 - 0.034 14.3 1.3 0.071 13.2 1.3 1.4 1 0 0 1 1 1 0 Podoplanin EphA2_TM PF14575.6 EAQ87587.1 - 0.2 12.6 0.0 1.1 10.2 0.0 2.2 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Syndecan PF01034.20 EAQ87587.1 - 0.21 11.5 0.5 0.55 10.2 0.5 1.6 1 0 0 1 1 1 0 Syndecan domain Mucin PF01456.17 EAQ87587.1 - 0.23 11.4 23.3 0.036 14.1 14.4 2.3 2 0 0 2 2 2 0 Mucin-like glycoprotein Cellulase PF00150.18 EAQ87588.1 - 3.1e-24 85.9 0.3 4e-24 85.5 0.3 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.17 EAQ87588.1 - 6.6e-06 25.4 0.1 1.3e-05 24.5 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain DUF4038 PF13204.6 EAQ87588.1 - 0.00044 20.0 1.8 0.00074 19.2 1.8 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF4038) Glyco_hydro_42 PF02449.15 EAQ87588.1 - 0.0025 17.2 0.8 0.0081 15.5 0.2 2.0 3 0 0 3 3 3 1 Beta-galactosidase DUF2255 PF10012.9 EAQ87588.1 - 0.065 13.4 0.3 0.14 12.3 0.3 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2255) zf-C2H2_4 PF13894.6 EAQ87590.1 - 0.00012 22.6 11.0 0.01 16.6 0.2 3.8 3 0 0 3 3 3 2 C2H2-type zinc finger zf_UBZ PF18439.1 EAQ87590.1 - 0.0065 16.0 0.3 1.5 8.5 0.0 2.6 2 0 0 2 2 2 2 Ubiquitin-Binding Zinc Finger zf-ribbon_3 PF13248.6 EAQ87590.1 - 0.018 14.4 0.7 1.4 8.4 0.0 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zf-met PF12874.7 EAQ87590.1 - 0.032 14.6 3.8 2.9 8.4 0.0 3.8 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 EAQ87590.1 - 0.064 13.7 12.8 0.12 12.9 0.4 3.3 3 0 0 3 3 3 0 Zinc finger, C2H2 type zinc_ribbon_9 PF14369.6 EAQ87590.1 - 0.12 12.7 3.4 0.68 10.2 0.1 2.7 2 0 0 2 2 2 0 zinc-ribbon zf-H2C2_2 PF13465.6 EAQ87590.1 - 0.17 12.4 5.9 0.18 12.3 0.6 2.9 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2_jaz PF12171.8 EAQ87590.1 - 0.58 10.5 2.4 14 6.1 0.1 3.2 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Pkinase PF00069.25 EAQ87592.1 - 1.1e-10 41.4 0.0 0.00036 20.0 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ87592.1 - 6.3e-05 22.4 0.0 0.00018 20.9 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase CorA PF01544.18 EAQ87594.1 - 3.1e-05 23.4 0.5 4.4e-05 23.0 0.5 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein TRIQK PF15168.6 EAQ87594.1 - 0.095 12.6 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Triple QxxK/R motif-containing protein family CcmD PF04995.14 EAQ87594.1 - 2.5 8.2 5.5 0.87 9.7 1.8 2.2 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) Gly_transf_sug PF04488.15 EAQ87596.1 - 8e-13 48.8 0.1 1.7e-12 47.8 0.1 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Band_3_cyto PF07565.13 EAQ87596.1 - 0.22 11.3 7.4 0.32 10.7 7.4 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain SAPS PF04499.15 EAQ87596.1 - 3.2 6.4 7.9 3.9 6.1 7.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF913 PF06025.12 EAQ87596.1 - 4.2 6.2 7.7 6 5.7 7.7 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DDHD PF02862.17 EAQ87596.1 - 4.4 7.4 8.1 2.2 8.4 6.0 1.6 2 0 0 2 2 2 0 DDHD domain DUF5427 PF10310.9 EAQ87596.1 - 4.6 6.1 22.6 5.9 5.7 22.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Oxidored_FMN PF00724.20 EAQ87598.1 - 1.2e-72 245.1 0.0 1.5e-72 244.8 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family SNF2_N PF00176.23 EAQ87599.1 - 6.5e-17 61.3 0.0 2.3e-08 33.1 0.0 2.2 2 0 0 2 2 2 2 SNF2 family N-terminal domain HIRAN PF08797.11 EAQ87599.1 - 5e-06 26.4 0.0 0.17 11.8 0.0 2.5 2 0 0 2 2 2 2 HIRAN domain AAA_34 PF13872.6 EAQ87599.1 - 0.00095 18.1 0.2 1.2 8.0 0.0 2.3 2 0 0 2 2 2 2 P-loop containing NTP hydrolase pore-1 Nup54 PF13874.6 EAQ87599.1 - 0.0026 17.8 2.8 1.5 8.9 0.2 2.4 2 0 0 2 2 2 2 Nucleoporin complex subunit 54 ROS_MUCR PF05443.11 EAQ87599.1 - 0.0074 16.3 0.0 6.6 6.8 0.0 2.7 2 0 0 2 2 2 2 ROS/MUCR transcriptional regulator protein RsbRD_N PF14361.6 EAQ87599.1 - 0.068 13.9 0.2 26 5.6 0.0 2.7 2 0 0 2 2 2 0 RsbT co-antagonist protein rsbRD N-terminal domain DUF3638 PF12340.8 EAQ87599.1 - 0.075 12.4 0.1 19 4.5 0.0 3.0 4 0 0 4 4 4 0 Protein of unknown function (DUF3638) Tobravirus_2B PF05271.11 EAQ87599.1 - 0.14 12.0 0.0 27 4.7 0.0 2.3 2 0 0 2 2 2 0 Tobravirus 2B protein RICH PF05062.12 EAQ87599.1 - 0.93 9.9 7.5 10 6.5 0.9 2.4 2 0 0 2 2 2 0 RICH domain SNF2_N PF00176.23 EAQ87602.1 - 6.2e-30 104.1 0.1 8.9e-30 103.6 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EAQ87602.1 - 7.1e-11 42.4 0.0 1.4e-10 41.5 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.6 EAQ87602.1 - 3.1e-06 27.0 2.7 8.6e-06 25.6 2.7 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EAQ87602.1 - 0.0042 17.1 1.6 0.0042 17.1 1.6 1.9 1 1 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 EAQ87602.1 - 0.0058 16.5 3.2 0.0089 15.9 1.7 2.1 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 EAQ87602.1 - 0.016 15.6 5.5 0.017 15.4 3.6 2.2 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4 PF00097.25 EAQ87602.1 - 0.03 14.2 3.4 0.11 12.4 3.4 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EAQ87602.1 - 0.062 13.5 1.5 0.2 11.8 1.5 1.9 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 EAQ87602.1 - 2.4 8.1 11.1 7.7 6.5 8.7 3.1 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) HET PF06985.11 EAQ87603.1 - 5.9e-26 91.6 0.0 1.2e-25 90.5 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) zf-H2C2_2 PF13465.6 EAQ87604.1 - 0.00029 21.1 1.3 0.00029 21.1 1.3 6.8 7 1 0 7 7 7 2 Zinc-finger double domain zf-C2H2 PF00096.26 EAQ87604.1 - 0.0006 20.1 28.3 0.0024 18.2 1.0 5.5 6 0 0 6 6 6 2 Zinc finger, C2H2 type zf-met PF12874.7 EAQ87604.1 - 0.00069 19.9 8.9 0.11 12.9 0.4 3.5 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 EAQ87604.1 - 0.0012 19.5 23.4 0.015 16.1 1.9 5.1 5 0 0 5 5 5 2 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 EAQ87604.1 - 0.14 12.3 2.9 3 8.0 1.3 3.4 2 1 1 3 3 3 0 Zinc ribbon domain zf-C2H2_11 PF16622.5 EAQ87604.1 - 0.3 10.9 1.5 2.8 7.8 0.2 2.8 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 EAQ87604.1 - 2 8.8 17.9 0.18 12.2 0.5 4.1 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 EAQ87604.1 - 4.3 7.4 8.2 8.1 6.6 1.0 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger Virul_fac_BrkB PF03631.15 EAQ87605.1 - 0.012 15.3 0.2 0.018 14.7 0.2 1.2 1 0 0 1 1 1 0 Virulence factor BrkB TMEM100 PF16311.5 EAQ87605.1 - 0.035 13.7 0.4 0.035 13.7 0.4 2.1 2 1 0 2 2 2 0 Transmembrane protein 100 DUF2207 PF09972.9 EAQ87605.1 - 0.056 12.2 0.1 0.071 11.9 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) UPF0093 PF03653.13 EAQ87605.1 - 0.068 13.4 0.2 0.12 12.6 0.2 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0093) ATP-synt_B PF00430.18 EAQ87605.1 - 0.13 12.3 7.1 1.2 9.3 3.9 2.5 2 1 0 2 2 2 0 ATP synthase B/B' CF(0) CdvA PF18822.1 EAQ87605.1 - 0.15 11.9 6.4 0.068 13.0 4.2 1.6 2 0 0 2 2 2 0 CdvA-like coiled-coil domain COX6C PF02937.15 EAQ87605.1 - 0.32 11.2 2.3 0.68 10.1 0.1 2.6 3 0 0 3 3 3 0 Cytochrome c oxidase subunit VIc CorA PF01544.18 EAQ87605.1 - 0.42 9.9 5.5 1.6 8.0 5.2 2.0 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein HSA PF07529.13 EAQ87605.1 - 1.5 9.2 7.2 3.6 8.0 2.5 2.6 2 0 0 2 2 2 0 HSA Pkinase PF00069.25 EAQ87607.1 - 2.8e-12 46.6 0.0 5.1e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ87607.1 - 1.1e-05 24.8 0.0 4.9e-05 22.7 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase zf-CCHC_6 PF15288.6 EAQ87608.1 - 0.055 13.3 2.0 0.25 11.2 2.0 2.2 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.6 EAQ87608.1 - 0.09 12.5 6.2 1.7 8.4 1.0 2.8 2 0 0 2 2 2 0 Zinc knuckle CAP59_mtransfer PF11735.8 EAQ87609.1 - 7.4e-64 215.7 0.0 1.8e-63 214.5 0.0 1.6 1 1 0 1 1 1 1 Cryptococcal mannosyltransferase 1 RdRP PF05183.12 EAQ87610.1 - 1.4e-96 324.4 0.0 2.6e-96 323.6 0.0 1.3 1 0 0 1 1 1 1 RNA dependent RNA polymerase AAA_11 PF13086.6 EAQ87610.1 - 3.6e-43 148.2 3.2 6.8e-21 75.2 1.6 2.3 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.6 EAQ87610.1 - 6.4e-13 48.9 0.0 1.6e-12 47.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAQ87610.1 - 1.2e-11 45.2 0.0 3e-11 43.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_12 PF13087.6 EAQ87610.1 - 3.7e-10 39.7 0.0 9.1e-10 38.5 0.0 1.7 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 EAQ87610.1 - 0.00015 21.8 0.0 0.00034 20.7 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.14 EAQ87610.1 - 0.0018 18.1 0.0 0.0033 17.3 0.0 1.4 1 0 0 1 1 1 1 Helicase UvrD-helicase PF00580.21 EAQ87610.1 - 0.0059 16.2 0.0 0.032 13.7 0.0 1.9 1 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA PF00004.29 EAQ87610.1 - 0.015 15.7 0.0 0.052 14.0 0.0 2.0 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DEAD PF00270.29 EAQ87610.1 - 0.022 14.5 0.0 0.07 12.9 0.0 1.9 2 0 0 2 2 2 0 DEAD/DEAH box helicase PhoH PF02562.16 EAQ87610.1 - 0.027 13.9 0.0 0.2 11.1 0.0 2.4 2 1 0 2 2 2 0 PhoH-like protein AAA_22 PF13401.6 EAQ87610.1 - 0.073 13.3 0.0 0.2 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EAQ87610.1 - 0.15 12.5 0.0 1.9 8.9 0.0 2.4 2 0 0 2 2 2 0 RNA helicase AAA_28 PF13521.6 EAQ87611.1 - 1.3e-11 45.0 0.0 3.3e-06 27.4 0.1 2.1 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EAQ87611.1 - 0.0049 17.3 0.0 0.048 14.0 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain TniB PF05621.11 EAQ87611.1 - 0.049 13.0 0.0 0.092 12.1 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Septin PF00735.18 EAQ87611.1 - 0.13 11.5 0.0 0.18 11.1 0.0 1.1 1 0 0 1 1 1 0 Septin ABC_ATPase PF09818.9 EAQ87611.1 - 0.23 10.2 0.0 0.31 9.8 0.0 1.1 1 0 0 1 1 1 0 Predicted ATPase of the ABC class AAA_14 PF13173.6 EAQ87611.1 - 0.26 11.3 0.0 0.38 10.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain Endonuc-dimeris PF09124.10 EAQ87612.1 - 0.081 13.1 0.0 0.19 11.9 0.0 1.6 1 0 0 1 1 1 0 T4 recombination endonuclease VII, dimerisation HSP70 PF00012.20 EAQ87613.1 - 0.0085 14.3 0.1 0.012 13.8 0.1 1.2 1 0 0 1 1 1 1 Hsp70 protein PepSY PF03413.19 EAQ87613.1 - 0.08 13.5 0.0 0.19 12.3 0.0 1.7 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain HD_3 PF13023.6 EAQ87614.1 - 4.8e-50 169.7 0.0 5.9e-50 169.4 0.0 1.1 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 EAQ87614.1 - 4.8e-10 39.5 0.0 6.6e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme DUF3433 PF11915.8 EAQ87616.1 - 1.2e-34 118.7 21.0 1.4e-17 63.9 5.5 3.4 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) CrgA PF06781.12 EAQ87616.1 - 0.14 12.2 2.6 3.6 7.7 0.0 2.9 2 0 0 2 2 2 0 Cell division protein CrgA Glyco_hydro_75 PF07335.11 EAQ87617.1 - 9.1e-17 61.8 0.0 2.2e-16 60.6 0.0 1.6 2 0 0 2 2 2 1 Fungal chitosanase of glycosyl hydrolase group 75 Nucleoporin_N PF08801.11 EAQ87619.1 - 9.4e-111 370.6 0.2 1.3e-110 370.2 0.2 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 EAQ87619.1 - 2.2e-48 165.4 1.2 4.3e-48 164.5 0.5 1.6 1 1 1 2 2 2 1 Non-repetitive/WGA-negative nucleoporin C-terminal adh_short PF00106.25 EAQ87620.1 - 3.8e-40 137.4 0.0 5.1e-40 137.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EAQ87620.1 - 1.9e-24 86.5 0.0 2.5e-24 86.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EAQ87620.1 - 3.9e-07 30.2 0.1 1.5e-06 28.3 0.1 1.8 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EAQ87620.1 - 0.031 14.2 0.0 0.052 13.4 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 EAQ87620.1 - 0.075 13.3 0.0 0.62 10.3 0.0 2.4 2 1 1 3 3 3 0 Saccharopine dehydrogenase NADP binding domain Polysacc_synt_2 PF02719.15 EAQ87620.1 - 0.19 10.8 0.0 0.29 10.2 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Erg28 PF03694.13 EAQ87621.1 - 7.4e-44 148.6 0.6 9.4e-44 148.3 0.6 1.1 1 0 0 1 1 1 1 Erg28 like protein GalP_UDP_transf PF01087.22 EAQ87622.1 - 4.2e-74 248.9 0.7 4.1e-73 245.7 0.4 2.1 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.17 EAQ87622.1 - 4.3e-59 199.0 0.0 9e-59 197.9 0.0 1.5 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain HIT PF01230.23 EAQ87622.1 - 0.0024 18.6 0.0 0.02 15.6 0.0 2.2 2 0 0 2 2 2 1 HIT domain HTH_ParB PF17762.1 EAQ87622.1 - 0.055 13.3 0.2 0.11 12.3 0.2 1.5 1 0 0 1 1 1 0 HTH domain found in ParB protein DUF4921 PF16268.5 EAQ87622.1 - 0.1 11.4 0.1 1.2 7.8 0.0 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4921) Myb_DNA-binding PF00249.31 EAQ87623.1 - 8.9e-09 35.4 0.0 2.8e-08 33.8 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain SWIRM PF04433.17 EAQ87623.1 - 4.1e-07 30.3 0.0 1.4e-06 28.5 0.0 1.8 1 0 0 1 1 1 1 SWIRM domain SHOCT PF09851.9 EAQ87623.1 - 0.025 14.3 0.6 0.096 12.5 0.6 2.1 1 0 0 1 1 1 0 Short C-terminal domain adh_short PF00106.25 EAQ87624.1 - 4.2e-14 52.5 0.0 5.5e-14 52.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EAQ87624.1 - 2e-13 50.5 0.0 2.5e-13 50.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Mg_trans_NIPA PF05653.14 EAQ87625.1 - 3.3e-90 302.2 24.8 4.3e-90 301.8 24.8 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 EAQ87625.1 - 9e-06 25.9 7.1 9e-06 25.9 7.1 3.1 3 0 0 3 3 3 1 EamA-like transporter family SLC35F PF06027.12 EAQ87625.1 - 0.0011 18.6 3.8 0.0011 18.6 3.8 2.1 2 0 0 2 2 2 1 Solute carrier family 35 DUF5362 PF17319.2 EAQ87625.1 - 0.75 9.7 0.0 0.75 9.7 0.0 2.9 3 0 0 3 3 3 0 Family of unknown function (DUF5362) DUF805 PF05656.14 EAQ87625.1 - 5.4 7.5 11.0 3.4 8.1 3.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF805) U-box PF04564.15 EAQ87626.1 - 1.4e-19 70.0 0.0 2.6e-19 69.2 0.0 1.5 1 0 0 1 1 1 1 U-box domain TPR_2 PF07719.17 EAQ87626.1 - 8.6e-10 38.0 3.5 0.067 13.3 0.1 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 EAQ87626.1 - 7.7e-07 29.7 13.5 5.3e-06 27.0 0.3 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 EAQ87626.1 - 5e-06 26.1 0.3 0.45 10.4 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 EAQ87626.1 - 1.1e-05 25.1 0.1 0.0027 17.3 0.0 2.5 1 1 1 2 2 2 1 TPR repeat TPR_19 PF14559.6 EAQ87626.1 - 1.4e-05 25.5 2.6 0.00034 21.1 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 EAQ87626.1 - 1.6e-05 25.0 1.3 5e-05 23.4 1.3 1.9 1 1 0 1 1 1 1 Tetratricopeptide repeat CHIP_TPR_N PF18391.1 EAQ87626.1 - 0.00061 20.5 1.6 0.00098 19.8 1.6 1.3 1 0 0 1 1 1 1 CHIP N-terminal tetratricopeptide repeat domain TPR_17 PF13431.6 EAQ87626.1 - 0.0013 19.0 1.5 0.14 12.6 0.0 3.2 3 1 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EAQ87626.1 - 0.012 15.8 0.8 0.021 15.0 0.8 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 PUMA PF15826.5 EAQ87626.1 - 0.017 15.3 1.4 0.031 14.5 1.4 1.3 1 0 0 1 1 1 0 Bcl-2-binding component 3, p53 upregulated modulator of apoptosis TPR_14 PF13428.6 EAQ87626.1 - 0.03 15.1 10.6 1.8 9.6 2.1 4.2 3 1 2 5 5 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 EAQ87626.1 - 0.03 14.6 9.7 0.4 11.0 5.7 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat zf-NOSIP PF15906.5 EAQ87626.1 - 0.055 13.6 0.0 0.26 11.4 0.0 1.9 2 0 0 2 2 2 0 Zinc-finger of nitric oxide synthase-interacting protein TPR_7 PF13176.6 EAQ87626.1 - 2.4 8.4 8.3 5.1 7.4 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat SH3_9 PF14604.6 EAQ87628.1 - 4.4e-09 36.1 0.0 7.9e-09 35.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EAQ87628.1 - 1.9e-05 24.1 0.0 3.2e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 SH3 domain Glycophorin_A PF01102.18 EAQ87628.1 - 0.026 14.8 0.0 0.067 13.4 0.0 1.7 1 0 0 1 1 1 0 Glycophorin A DUF4569 PF15133.6 EAQ87628.1 - 0.043 13.5 0.0 0.078 12.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) Amnionless PF14828.6 EAQ87628.1 - 0.08 11.8 0.0 0.12 11.2 0.0 1.1 1 0 0 1 1 1 0 Amnionless Yip1 PF04893.17 EAQ87628.1 - 0.084 12.6 0.1 0.13 11.9 0.1 1.2 1 0 0 1 1 1 0 Yip1 domain DUF5305 PF17231.2 EAQ87628.1 - 0.099 12.0 0.1 0.15 11.4 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5305) RIFIN PF02009.16 EAQ87628.1 - 0.13 12.1 0.0 0.18 11.7 0.0 1.1 1 0 0 1 1 1 0 Rifin Plasmodium_Vir PF05795.11 EAQ87628.1 - 0.13 11.6 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Mid2 PF04478.12 EAQ87628.1 - 0.16 11.8 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor TMEM154 PF15102.6 EAQ87628.1 - 0.32 10.9 0.9 1 9.3 0.1 1.9 2 0 0 2 2 2 0 TMEM154 protein family Gar1 PF04410.14 EAQ87630.1 - 1.1e-48 164.9 0.5 1.1e-48 164.9 0.5 1.8 3 0 0 3 3 3 1 Gar1/Naf1 RNA binding region Glyco_transf_22 PF03901.17 EAQ87631.1 - 4.5e-87 293.0 20.1 5.3e-87 292.8 20.1 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family TAP35_44 PF07265.11 EAQ87631.1 - 0.1 12.6 0.0 0.34 10.9 0.0 1.8 1 0 0 1 1 1 0 Tapetum specific protein TAP35/TAP44 F-box-like PF12937.7 EAQ87632.1 - 3.5e-08 33.2 0.6 0.0039 17.0 0.0 2.8 3 0 0 3 3 3 2 F-box-like F-box PF00646.33 EAQ87632.1 - 6.1e-05 22.8 0.1 0.2 11.6 0.0 2.7 2 0 0 2 2 2 2 F-box domain RNA_pol_Rpb2_5 PF04567.17 EAQ87632.1 - 0.2 12.3 3.1 0.24 12.0 0.8 2.2 3 0 0 3 3 3 0 RNA polymerase Rpb2, domain 5 Exo5 PF09810.9 EAQ87633.1 - 2e-125 419.2 0.0 4.1e-125 418.1 0.0 1.5 2 0 0 2 2 2 1 Exonuclease V - a 5' deoxyribonuclease PDDEXK_1 PF12705.7 EAQ87633.1 - 2.3e-05 24.5 0.0 0.25 11.2 0.0 3.2 3 0 0 3 3 3 2 PD-(D/E)XK nuclease superfamily Csa1 PF06023.12 EAQ87633.1 - 0.23 10.8 0.0 0.41 9.9 0.0 1.4 1 0 0 1 1 1 0 CRISPR-associated exonuclease Csa1 ProRS-C_1 PF09180.11 EAQ87634.1 - 2.3e-22 79.0 0.2 4.5e-22 78.0 0.2 1.5 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.25 EAQ87634.1 - 2.3e-20 73.3 0.0 4.9e-20 72.2 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EAQ87634.1 - 3.8e-15 55.8 0.0 8.3e-15 54.7 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain DnaB_2 PF07261.11 EAQ87634.1 - 0.2 11.4 1.2 0.7 9.7 0.5 2.2 2 0 0 2 2 2 0 Replication initiation and membrane attachment Cpn60_TCP1 PF00118.24 EAQ87635.1 - 1.3e-151 505.5 14.0 1.5e-151 505.4 14.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Phage_int_SAM_1 PF02899.17 EAQ87635.1 - 0.18 12.1 0.1 0.79 10.1 0.0 2.1 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain Acetyltransf_7 PF13508.7 EAQ87636.1 - 3.6e-05 24.1 0.0 8.9e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EAQ87636.1 - 0.0031 17.6 0.2 0.011 15.8 0.1 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EAQ87636.1 - 0.007 16.6 0.1 0.022 15.0 0.1 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 EAQ87636.1 - 0.0099 15.8 0.0 0.039 13.9 0.0 2.1 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 EAQ87636.1 - 0.03 14.2 0.1 0.12 12.4 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EAQ87636.1 - 0.031 14.4 0.0 0.07 13.3 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase AFG1_ATPase PF03969.16 EAQ87638.1 - 3.9e-96 322.1 0.0 6.1e-92 308.3 0.0 2.2 2 0 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.6 EAQ87638.1 - 3.8e-05 24.1 1.1 0.022 15.1 0.0 3.1 2 1 0 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 EAQ87638.1 - 0.00096 19.2 0.0 0.0023 17.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 EAQ87638.1 - 0.0011 19.0 0.0 0.0023 18.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EAQ87638.1 - 0.0069 16.7 0.0 0.04 14.2 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA PF00004.29 EAQ87638.1 - 0.0086 16.5 0.0 0.022 15.2 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 EAQ87638.1 - 0.045 13.7 0.0 0.18 11.7 0.0 2.1 1 1 0 1 1 1 0 NACHT domain TsaE PF02367.17 EAQ87638.1 - 0.05 13.6 0.0 0.093 12.7 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Bac_DnaA PF00308.18 EAQ87638.1 - 0.077 12.8 0.3 1.5 8.6 0.1 2.8 3 1 0 3 3 3 0 Bacterial dnaA protein FLYWCH_u PF16662.5 EAQ87638.1 - 0.085 12.9 1.2 0.22 11.6 1.2 1.6 1 0 0 1 1 1 0 FLYWCH-type zinc finger-containing protein 1 RNA_helicase PF00910.22 EAQ87638.1 - 0.13 12.6 0.0 0.41 11.1 0.0 1.8 2 0 0 2 2 2 0 RNA helicase Peptidase_M28 PF04389.17 EAQ87639.1 - 6e-28 97.9 0.0 9.3e-28 97.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 EAQ87639.1 - 1.3e-05 25.0 0.1 3.2e-05 23.7 0.1 1.7 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 PLDc_2 PF13091.6 EAQ87640.1 - 6.3e-18 65.0 0.0 4.1e-08 33.2 0.0 2.5 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 EAQ87640.1 - 0.0021 18.2 0.1 0.14 12.3 0.1 2.6 2 0 0 2 2 2 1 Phospholipase D Active site motif Regulator_TrmB PF11495.8 EAQ87640.1 - 0.13 11.5 0.0 2.9 7.0 0.0 2.5 2 0 0 2 2 2 0 Archaeal transcriptional regulator TrmB NUC153 PF08159.12 EAQ87643.1 - 5.4e-15 54.9 7.0 3.2e-14 52.4 0.3 3.5 3 0 0 3 3 3 2 NUC153 domain TTL PF03133.15 EAQ87644.1 - 2.4e-18 66.3 0.0 4e-18 65.6 0.0 1.3 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family Glyco_hydro_62 PF03664.13 EAQ87645.1 - 8.6e-147 487.7 13.6 1.1e-146 487.4 13.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 CBM_1 PF00734.18 EAQ87645.1 - 2.2e-13 49.9 12.0 5e-13 48.8 12.0 1.7 1 0 0 1 1 1 1 Fungal cellulose binding domain Glyco_hydro_62 PF03664.13 EAQ87646.1 - 3.6e-67 226.5 0.9 4.8e-67 226.1 0.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 CBM_1 PF00734.18 EAQ87646.1 - 1e-13 51.0 12.0 2.3e-13 49.8 12.0 1.7 1 0 0 1 1 1 1 Fungal cellulose binding domain UPF0552 PF10574.9 EAQ87646.1 - 0.13 11.6 0.4 0.25 10.6 0.2 1.5 1 1 0 1 1 1 0 Arp2/3-interacting proteins Arpin Ifi-6-16 PF06140.13 EAQ87648.1 - 1.9e-07 30.9 28.8 1.9e-07 30.9 28.8 2.2 1 1 1 2 2 2 1 Interferon-induced 6-16 family eIF3g PF12353.8 EAQ87648.1 - 0.0022 18.4 0.2 0.0037 17.7 0.1 1.4 1 1 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G zf-C2HC_2 PF13913.6 EAQ87648.1 - 0.022 14.6 0.0 0.044 13.7 0.0 1.5 1 0 0 1 1 1 0 zinc-finger of a C2HC-type Amnionless PF14828.6 EAQ87648.1 - 0.16 10.8 0.0 0.2 10.5 0.0 1.1 1 0 0 1 1 1 0 Amnionless Promethin PF16015.5 EAQ87648.1 - 2.4 8.1 6.4 6.9 6.6 6.4 1.9 1 1 0 1 1 1 0 Promethin Sporozoite_P67 PF05642.11 EAQ87648.1 - 6.3 4.8 10.2 8.1 4.4 10.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Methyltransf_25 PF13649.6 EAQ87649.1 - 2.7e-08 34.4 0.1 8.4e-08 32.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EAQ87649.1 - 5.4e-08 33.4 0.0 1.4e-07 32.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EAQ87649.1 - 4.8e-06 26.1 0.0 7.9e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 EAQ87649.1 - 1.5e-05 24.9 0.0 2.2e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EAQ87649.1 - 0.0011 19.7 0.0 0.0029 18.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain FAR1 PF03101.15 EAQ87650.1 - 0.079 13.7 1.6 0.093 13.4 0.4 1.7 2 0 0 2 2 2 0 FAR1 DNA-binding domain Cyt-b5 PF00173.28 EAQ87651.1 - 5.5e-11 42.5 2.8 1.1e-09 38.3 0.3 3.2 2 2 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FYTT PF07078.11 EAQ87651.1 - 0.13 11.5 0.5 0.17 11.2 0.5 1.1 1 0 0 1 1 1 0 Forty-two-three protein c-SKI_SMAD_bind PF08782.10 EAQ87651.1 - 0.14 12.4 0.0 0.22 11.8 0.0 1.3 1 0 0 1 1 1 0 c-SKI Smad4 binding domain RT_RNaseH PF17917.1 EAQ87652.1 - 4.1e-39 133.1 0.0 9.4e-39 131.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 EAQ87652.1 - 8.6e-34 115.6 0.0 2.5e-33 114.1 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 EAQ87652.1 - 1.4e-30 106.5 0.0 2.7e-30 105.5 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 EAQ87652.1 - 2e-13 50.2 0.4 1e-12 47.9 0.0 2.2 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 EAQ87652.1 - 2.1e-13 50.5 1.2 3.5e-13 49.8 0.1 2.0 3 0 0 3 3 3 1 Integrase core domain Chromo PF00385.24 EAQ87652.1 - 3.1e-05 23.8 0.1 0.0002 21.2 0.0 2.5 3 0 0 3 3 3 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 EAQ87652.1 - 0.00013 22.1 0.0 0.00033 20.8 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger DUF4232 PF14016.6 EAQ87653.1 - 0.051 13.7 0.2 0.13 12.4 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4232) FAD_binding_3 PF01494.19 EAQ87654.1 - 2.7e-18 66.4 0.2 1.5e-17 63.9 0.2 2.2 1 1 0 1 1 1 1 FAD binding domain Methyltransf_23 PF13489.6 EAQ87654.1 - 3e-10 40.2 0.1 4.5e-09 36.3 0.0 2.8 3 1 0 3 3 3 1 Methyltransferase domain NAD_binding_8 PF13450.6 EAQ87654.1 - 2.9e-08 33.8 0.1 7.7e-08 32.5 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Methyltransf_25 PF13649.6 EAQ87654.1 - 4.1e-06 27.4 0.0 1.7e-05 25.4 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EAQ87654.1 - 6.7e-06 26.7 0.0 3e-05 24.6 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain FAD_binding_2 PF00890.24 EAQ87654.1 - 0.00024 20.3 0.3 0.00049 19.3 0.3 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EAQ87654.1 - 0.00035 19.9 0.0 0.0023 17.2 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EAQ87654.1 - 0.00039 20.1 0.2 0.0014 18.3 0.2 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase Methyltransf_12 PF08242.12 EAQ87654.1 - 0.0029 18.3 0.0 0.014 16.1 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain HI0933_like PF03486.14 EAQ87654.1 - 0.0041 15.9 0.1 0.0076 15.0 0.1 1.4 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 EAQ87654.1 - 0.0048 17.4 0.0 0.038 14.6 0.0 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EAQ87654.1 - 0.0079 15.3 0.1 2 7.3 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 EAQ87654.1 - 0.0094 15.3 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 EAQ87654.1 - 0.011 15.0 0.1 0.026 13.7 0.1 1.6 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.22 EAQ87654.1 - 0.08 12.0 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Shikimate_DH PF01488.20 EAQ87654.1 - 0.1 12.6 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Wx5_PLAF3D7 PF09688.10 EAQ87654.1 - 0.1 12.6 0.2 0.19 11.7 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (Wx5_PLAF3D7) ApbA PF02558.16 EAQ87654.1 - 0.14 11.8 0.1 0.29 10.8 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.6 EAQ87654.1 - 0.17 11.1 0.0 0.35 10.1 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase zf-PHD-like PF15446.6 EAQ87656.1 - 0.007 16.0 3.3 0.01 15.5 3.3 1.2 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain Prefoldin PF02996.17 EAQ87656.1 - 0.014 15.3 0.4 0.024 14.5 0.4 1.4 1 0 0 1 1 1 0 Prefoldin subunit DUF2852 PF11014.8 EAQ87656.1 - 0.22 11.7 6.7 0.54 10.4 6.7 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2852) Tho2 PF11262.8 EAQ87656.1 - 0.33 10.1 2.0 0.48 9.6 2.0 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 FUSC PF04632.12 EAQ87656.1 - 0.34 9.4 1.6 0.38 9.2 1.6 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Cyclin_N PF00134.23 EAQ87657.1 - 3.1e-08 33.4 0.0 5.6e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Receptor_IA-2 PF11548.8 EAQ87657.1 - 0.055 13.4 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein-tyrosine phosphatase receptor IA-2 CECR6_TMEM121 PF14997.6 EAQ87657.1 - 0.24 11.2 0.2 0.36 10.6 0.2 1.2 1 0 0 1 1 1 0 CECR6/TMEM121 family NmrA PF05368.13 EAQ87658.1 - 2.8e-47 161.2 0.0 3.3e-47 161.0 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EAQ87658.1 - 3e-10 40.3 2.2 6.8e-10 39.1 1.8 1.7 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 EAQ87658.1 - 0.0003 20.3 0.1 0.00048 19.7 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 EAQ87658.1 - 0.023 14.9 0.1 0.073 13.3 0.1 1.8 2 1 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 EAQ87658.1 - 0.025 14.8 0.1 0.044 14.0 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain DUF5631 PF18645.1 EAQ87659.1 - 0.0018 18.6 0.1 0.0067 16.8 0.1 1.9 1 0 0 1 1 1 1 Family of unknown function (DUF5631) Tegument_dsDNA PF12818.7 EAQ87659.1 - 0.012 14.8 0.1 0.029 13.5 0.0 1.7 1 1 0 1 1 1 0 dsDNA viral tegument protein GREB1 PF15782.5 EAQ87659.1 - 0.35 7.9 0.6 0.45 7.6 0.6 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Menin PF05053.13 EAQ87659.1 - 0.47 8.8 2.2 0.67 8.2 2.2 1.1 1 0 0 1 1 1 0 Menin SOG2 PF10428.9 EAQ87659.1 - 1.9 7.6 7.8 2.8 7.0 7.8 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Mucin PF01456.17 EAQ87659.1 - 2.1 8.3 17.9 4.1 7.4 17.9 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein FBPase PF00316.20 EAQ87660.1 - 3.5e-17 62.5 0.0 9.4e-17 61.1 0.0 1.6 2 0 0 2 2 2 1 Fructose-1-6-bisphosphatase, N-terminal domain ANAPC3 PF12895.7 EAQ87662.1 - 0.0034 17.6 0.0 0.01 16.1 0.0 1.8 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 EAQ87662.1 - 0.0041 17.6 0.1 1.6 9.3 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat OpuAC PF04069.12 EAQ87666.1 - 0.084 12.4 0.0 0.088 12.4 0.0 1.1 1 0 0 1 1 1 0 Substrate binding domain of ABC-type glycine betaine transport system RVT_1 PF00078.27 EAQ87667.1 - 7.9e-33 113.8 0.0 1.3e-32 113.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 EAQ87667.1 - 7.9e-06 25.7 0.0 1.8e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase zf-RVT PF13966.6 EAQ87667.1 - 0.12 13.1 0.0 0.41 11.4 0.0 1.9 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase zf-CCHC PF00098.23 EAQ87667.1 - 0.31 11.2 2.5 2 8.6 0.7 2.9 2 0 0 2 2 2 0 Zinc knuckle Brix PF04427.18 EAQ87668.1 - 3.6e-48 164.3 0.0 4.9e-48 163.8 0.0 1.2 1 0 0 1 1 1 1 Brix domain DEAD PF00270.29 EAQ87669.1 - 4e-49 166.7 0.0 5.9e-49 166.2 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EAQ87669.1 - 5.7e-29 100.7 0.0 2.2e-28 98.8 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EAQ87669.1 - 7.4e-06 26.1 0.0 1.3e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CwfJ_C_2 PF04676.14 EAQ87670.1 - 4e-29 101.4 0.1 4e-29 101.4 0.1 2.2 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 2 CwfJ_C_1 PF04677.15 EAQ87670.1 - 7.5e-24 83.9 0.0 1.6e-23 82.9 0.0 1.6 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 FumaraseC_C PF10415.9 EAQ87670.1 - 0.01 16.2 0.6 0.13 12.7 0.2 2.7 2 0 0 2 2 2 0 Fumarase C C-terminus SASP PF00269.20 EAQ87671.1 - 0.064 13.3 0.1 0.17 12.0 0.1 1.7 1 0 0 1 1 1 0 Small, acid-soluble spore proteins, alpha/beta type ATP_bind_1 PF03029.17 EAQ87672.1 - 1.2e-73 247.9 0.0 1.8e-73 247.3 0.0 1.3 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 EAQ87672.1 - 2.5e-05 23.9 0.0 0.0032 17.1 0.0 2.9 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Arf PF00025.21 EAQ87672.1 - 3.2e-05 23.5 0.0 0.13 11.7 0.0 3.0 2 1 0 2 2 2 2 ADP-ribosylation factor family MeaB PF03308.16 EAQ87672.1 - 9.5e-05 21.5 0.1 0.015 14.3 0.0 2.3 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 EAQ87672.1 - 0.0002 21.4 0.0 0.0018 18.4 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 EAQ87672.1 - 0.00053 20.2 0.0 0.025 14.8 0.0 2.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EAQ87672.1 - 0.0011 18.6 0.0 1.8 8.1 0.0 2.7 2 1 0 2 2 2 2 Ras family RsgA_GTPase PF03193.16 EAQ87672.1 - 0.0014 18.5 2.0 2 8.3 0.0 3.9 4 1 0 4 4 4 2 RsgA GTPase AAA_33 PF13671.6 EAQ87672.1 - 0.002 18.3 1.1 0.0059 16.8 0.0 2.2 2 1 0 2 2 2 1 AAA domain FeoB_N PF02421.18 EAQ87672.1 - 0.0026 17.3 0.0 0.16 11.5 0.0 2.8 3 0 0 3 3 3 1 Ferrous iron transport protein B AAA_22 PF13401.6 EAQ87672.1 - 0.0037 17.5 0.0 0.023 15.0 0.0 2.4 2 1 1 3 3 3 1 AAA domain NB-ARC PF00931.22 EAQ87672.1 - 0.0063 15.7 0.0 0.016 14.4 0.0 1.6 2 0 0 2 2 2 1 NB-ARC domain AAA_24 PF13479.6 EAQ87672.1 - 0.0069 16.1 0.0 0.023 14.4 0.0 1.9 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EAQ87672.1 - 0.011 15.4 0.0 0.024 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 EAQ87672.1 - 0.012 15.2 0.0 1.8 8.2 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 EAQ87672.1 - 0.016 15.1 0.0 0.029 14.3 0.0 1.4 1 0 0 1 1 1 0 NACHT domain SRPRB PF09439.10 EAQ87672.1 - 0.024 14.1 0.0 8 5.9 0.0 2.4 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit SRP54 PF00448.22 EAQ87672.1 - 0.027 14.1 0.0 0.11 12.2 0.0 1.9 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_16 PF13191.6 EAQ87672.1 - 0.043 14.2 0.0 0.21 12.0 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain PduV-EutP PF10662.9 EAQ87672.1 - 0.091 12.5 0.1 0.56 10.0 0.0 2.3 3 1 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_14 PF13173.6 EAQ87672.1 - 0.14 12.2 0.0 0.33 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EAQ87672.1 - 0.16 12.5 3.3 0.4 11.2 0.0 2.6 2 1 0 2 2 2 0 AAA domain DNA_RNApol_7kD PF03604.13 EAQ87673.1 - 1.8e-14 53.1 4.8 2.3e-14 52.8 4.8 1.2 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit GFA PF04828.14 EAQ87673.1 - 0.0055 17.0 0.7 1.4 9.3 0.0 2.1 1 1 1 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme zf_UBZ PF18439.1 EAQ87673.1 - 0.0059 16.2 0.8 2.9 7.6 0.1 2.2 2 0 0 2 2 2 2 Ubiquitin-Binding Zinc Finger DUF3268 PF11672.8 EAQ87673.1 - 0.014 15.8 0.5 0.11 12.8 0.5 1.9 1 1 0 1 1 1 0 zinc-finger-containing domain DZR PF12773.7 EAQ87673.1 - 0.027 14.5 0.3 0.036 14.1 0.3 1.3 1 0 0 1 1 1 0 Double zinc ribbon zinc-ribbon_6 PF10005.9 EAQ87673.1 - 0.032 14.9 0.1 0.04 14.6 0.1 1.1 1 0 0 1 1 1 0 zinc-ribbon domain HypA PF01155.19 EAQ87673.1 - 0.039 14.0 0.4 0.049 13.6 0.4 1.1 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA C1_1 PF00130.22 EAQ87673.1 - 0.071 13.0 0.4 0.11 12.5 0.4 1.2 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF2197 PF09963.9 EAQ87673.1 - 0.17 12.2 1.7 3.2 8.1 0.1 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) Aldo_ket_red PF00248.21 EAQ87674.1 - 3.5e-19 69.1 0.0 3.3e-17 62.6 0.0 2.3 1 1 0 1 1 1 1 Aldo/keto reductase family Myb_DNA-bind_5 PF13873.6 EAQ87674.1 - 0.11 12.5 0.6 0.23 11.6 0.1 1.8 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain ChAPs PF09295.10 EAQ87675.1 - 2.8e-152 507.3 0.0 3.5e-152 507.0 0.0 1.1 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_14 PF13428.6 EAQ87675.1 - 9.7e-06 26.0 0.6 0.26 12.2 0.5 4.7 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 EAQ87675.1 - 0.00059 19.8 0.4 0.083 13.1 0.6 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 EAQ87675.1 - 0.00081 19.2 0.3 0.85 9.8 0.1 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 EAQ87675.1 - 0.0021 18.1 0.0 0.52 10.7 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 EAQ87675.1 - 0.0032 17.6 0.1 0.89 9.7 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 EAQ87675.1 - 0.02 15.4 0.0 9 6.9 0.0 3.3 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 EAQ87675.1 - 0.049 13.5 0.1 9.7 6.2 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 EAQ87675.1 - 0.13 12.9 0.1 54 4.7 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 EAQ87676.1 - 0.31 11.2 1.8 1.6 8.9 1.8 2.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_16 PF13432.6 EAQ87676.1 - 0.74 10.5 14.2 7.3 7.3 0.4 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat UQ_con PF00179.26 EAQ87677.1 - 9.1e-40 135.5 0.0 1.1e-39 135.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EAQ87677.1 - 0.0085 15.8 0.0 0.012 15.4 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RabGAP-TBC PF00566.18 EAQ87678.1 - 1.9e-31 109.4 0.9 3.4e-18 66.1 0.0 2.9 2 1 0 2 2 2 2 Rab-GTPase-TBC domain ALIX_LYPXL_bnd PF13949.6 EAQ87679.1 - 0.13 11.6 0.3 0.21 10.8 0.3 1.3 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV CDC45 PF02724.14 EAQ87680.1 - 0.006 15.0 14.6 0.0072 14.7 14.6 1.0 1 0 0 1 1 1 1 CDC45-like protein Nop14 PF04147.12 EAQ87680.1 - 0.025 12.8 10.1 0.03 12.5 10.1 1.2 1 0 0 1 1 1 0 Nop14-like family eIF-3c_N PF05470.12 EAQ87680.1 - 4.9 5.3 7.3 5.7 5.1 7.3 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus HsbA PF12296.8 EAQ87682.1 - 3.1e-25 88.9 2.4 4.3e-25 88.5 2.4 1.1 1 0 0 1 1 1 1 Hydrophobic surface binding protein A EI24 PF07264.11 EAQ87683.1 - 0.022 15.0 4.3 0.041 14.1 4.3 1.4 1 1 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) DUF4668 PF15701.5 EAQ87683.1 - 0.029 14.2 0.4 0.25 11.2 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4668) DUF4231 PF14015.6 EAQ87683.1 - 0.051 14.1 1.7 0.24 11.9 1.7 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF4231) DUF5325 PF17259.2 EAQ87683.1 - 0.36 10.7 0.1 0.36 10.7 0.1 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5325) DUF4870 PF09685.10 EAQ87683.1 - 0.39 10.9 5.0 0.14 12.3 0.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4870) DUF1218 PF06749.12 EAQ87683.1 - 0.45 11.1 3.6 1.6 9.3 0.9 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1218) Tetraspanin PF00335.20 EAQ87683.1 - 1.7 8.3 4.4 1.9 8.1 1.1 2.0 2 0 0 2 2 2 0 Tetraspanin family Peptidase_S24 PF00717.23 EAQ87684.1 - 2.4e-07 30.6 0.0 3.8e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like AAA_22 PF13401.6 EAQ87685.1 - 1.4e-05 25.4 0.0 0.00027 21.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 EAQ87685.1 - 0.00015 21.8 0.0 0.00033 20.7 0.0 1.5 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_16 PF13191.6 EAQ87685.1 - 0.00099 19.5 0.0 0.0034 17.8 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.22 EAQ87685.1 - 0.006 17.0 0.1 0.087 13.2 0.1 2.6 3 0 0 3 3 3 1 RNA helicase AAA_29 PF13555.6 EAQ87685.1 - 0.012 15.3 0.0 0.051 13.3 0.0 2.0 1 0 0 1 1 1 0 P-loop containing region of AAA domain NACHT PF05729.12 EAQ87685.1 - 0.014 15.4 0.6 0.072 13.0 0.6 2.4 1 1 0 1 1 1 0 NACHT domain NB-ARC PF00931.22 EAQ87685.1 - 0.056 12.6 0.0 0.12 11.5 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain ABC_tran PF00005.27 EAQ87685.1 - 0.061 13.8 0.0 0.2 12.1 0.0 1.8 1 0 0 1 1 1 0 ABC transporter AAA_18 PF13238.6 EAQ87685.1 - 0.066 13.8 0.0 0.21 12.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain Trehalase PF01204.18 EAQ87685.1 - 0.12 11.2 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 Trehalase NTPase_1 PF03266.15 EAQ87685.1 - 0.15 12.0 0.0 0.34 10.8 0.0 1.6 1 0 0 1 1 1 0 NTPase AAA_19 PF13245.6 EAQ87685.1 - 0.16 12.3 0.1 0.77 10.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain BTB PF00651.31 EAQ87686.1 - 8.6e-07 29.2 0.0 2.4e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain NitrOD5 PF11537.8 EAQ87686.1 - 0.011 15.9 0.0 0.92 9.7 0.0 2.6 3 0 0 3 3 3 0 Nitrosopumilus output domain 5 DUF1349 PF07081.11 EAQ87687.1 - 1.3e-18 67.4 0.0 6.5e-18 65.1 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1349) TFIIB PF00382.19 EAQ87688.1 - 1.4e-28 98.7 2.7 6.6e-15 54.9 0.3 2.6 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.13 EAQ87688.1 - 1.1e-17 64.2 1.5 1.6e-17 63.7 0.2 2.1 2 0 0 2 2 2 1 Brf1-like TBP-binding domain Cyclin_N PF00134.23 EAQ87688.1 - 0.01 15.6 0.4 0.052 13.3 0.0 2.1 1 1 0 2 2 2 1 Cyclin, N-terminal domain Lipase_GDSL_2 PF13472.6 EAQ87690.1 - 1.1e-20 74.8 1.3 1.8e-20 74.1 1.3 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EAQ87690.1 - 2e-08 34.5 0.0 3.6e-08 33.6 0.0 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 EAQ87690.1 - 0.0002 21.5 0.0 0.00046 20.4 0.0 1.5 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Zn_peptidase_2 PF04298.12 EAQ87691.1 - 0.069 12.5 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 Putative neutral zinc metallopeptidase GFA PF04828.14 EAQ87693.1 - 2.6e-21 75.7 0.3 3.9e-21 75.2 0.3 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme PhoLip_ATPase_C PF16212.5 EAQ87694.1 - 1.6e-40 139.5 5.5 7.4e-38 130.7 0.6 3.1 2 1 1 3 3 3 2 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EAQ87694.1 - 1.7e-22 78.9 3.0 2.4e-22 78.4 0.8 2.3 3 0 0 3 3 3 1 Phospholipid-translocating ATPase N-terminal E1-E2_ATPase PF00122.20 EAQ87694.1 - 6.3e-12 45.4 0.0 1.4e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 EAQ87694.1 - 2.7e-11 44.2 2.3 2.6e-06 27.9 0.0 3.6 2 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EAQ87694.1 - 3.7e-11 42.9 0.0 4.3e-10 39.6 0.0 2.3 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EAQ87694.1 - 0.0028 17.5 0.0 0.012 15.3 0.0 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Dynamin_N PF00350.23 EAQ87695.1 - 1.5e-21 77.1 0.2 3.9e-15 56.3 0.0 2.6 2 0 0 2 2 2 2 Dynamin family Dynamin_M PF01031.20 EAQ87695.1 - 1.3e-10 41.0 0.0 6e-10 38.8 0.0 2.0 2 1 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.23 EAQ87695.1 - 0.00032 20.8 0.0 0.0011 19.0 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_15 PF13175.6 EAQ87695.1 - 0.037 13.7 0.0 0.063 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain DUF3666 PF12408.8 EAQ87695.1 - 0.061 12.5 0.0 0.18 11.0 0.0 1.8 1 0 0 1 1 1 0 Ribose-5-phosphate isomerase GED PF02212.18 EAQ87695.1 - 0.92 9.7 2.6 1.3 9.2 0.4 2.5 3 0 0 3 3 3 0 Dynamin GTPase effector domain adh_short_C2 PF13561.6 EAQ87696.1 - 8.5e-50 169.5 5.7 2.5e-38 132.0 0.5 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EAQ87696.1 - 8.1e-39 133.1 0.2 1.2e-38 132.5 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EAQ87696.1 - 1.1e-05 25.4 0.6 3.7e-05 23.7 0.3 1.8 2 0 0 2 2 2 1 KR domain YjeF_N PF03853.15 EAQ87696.1 - 0.0027 17.6 0.2 0.0056 16.6 0.2 1.5 1 0 0 1 1 1 1 YjeF-related protein N-terminus THF_DHG_CYH_C PF02882.19 EAQ87696.1 - 0.047 13.0 0.6 0.11 11.8 0.6 1.7 1 1 1 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain AdoHcyase_NAD PF00670.21 EAQ87696.1 - 0.084 12.9 1.3 0.2 11.7 1.3 1.7 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain DUF4888 PF16229.5 EAQ87696.1 - 0.1 12.6 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4888) Vps35 PF03635.17 EAQ87697.1 - 0 1021.0 0.0 0 1020.8 0.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 DUF3915 PF13054.6 EAQ87697.1 - 0.35 10.9 1.9 0.45 10.5 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) Vpu PF00558.19 EAQ87697.1 - 0.35 10.7 1.4 1.2 8.9 1.4 1.9 1 0 0 1 1 1 0 Vpu protein TFR_dimer PF04253.15 EAQ87698.1 - 2.8e-31 108.1 0.0 5.9e-31 107.1 0.0 1.6 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 EAQ87698.1 - 2.2e-14 53.6 0.0 1.4e-13 51.0 0.0 2.1 2 0 0 2 2 2 1 Peptidase family M28 PA PF02225.22 EAQ87698.1 - 8.8e-12 44.9 0.0 1.7e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 PA domain DUF4911 PF16256.5 EAQ87698.1 - 0.17 11.9 0.0 0.36 10.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4911) TENA_THI-4 PF03070.16 EAQ87699.1 - 6.1e-06 26.2 0.0 0.00022 21.1 0.0 2.4 2 0 0 2 2 2 1 TENA/THI-4/PQQC family AAA PF00004.29 EAQ87699.1 - 0.006 17.0 0.0 0.021 15.3 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) FMO-like PF00743.19 EAQ87700.1 - 5.8e-12 44.8 0.0 8.8e-12 44.2 0.0 1.2 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EAQ87700.1 - 3.5e-11 42.9 0.0 5.8e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EAQ87700.1 - 2.7e-09 36.6 0.0 5.1e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 EAQ87700.1 - 0.00041 19.7 0.0 0.0029 16.9 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Cadherin_C PF01049.17 EAQ87701.1 - 0.0042 17.4 0.1 0.0042 17.4 0.1 1.5 2 0 0 2 2 2 1 Cadherin cytoplasmic region Guanylate_kin PF00625.21 EAQ87702.1 - 9.9e-62 207.8 0.0 1.1e-61 207.7 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_33 PF13671.6 EAQ87702.1 - 8.8e-08 32.4 0.1 1.2e-06 28.7 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EAQ87702.1 - 0.00027 21.5 0.1 0.00086 19.9 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EAQ87702.1 - 0.0012 19.2 0.1 0.0019 18.6 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EAQ87702.1 - 0.0044 17.3 0.0 0.012 15.9 0.0 1.7 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EAQ87702.1 - 0.0072 16.3 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_28 PF13521.6 EAQ87702.1 - 0.015 15.5 0.2 0.37 11.0 0.2 2.3 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EAQ87702.1 - 0.027 15.0 0.0 0.034 14.7 0.0 1.4 1 1 0 1 1 1 0 ABC transporter dNK PF01712.19 EAQ87702.1 - 0.031 14.1 0.2 3.8 7.3 0.0 2.5 2 1 1 3 3 3 0 Deoxynucleoside kinase MMR_HSR1 PF01926.23 EAQ87702.1 - 0.048 13.7 0.1 0.13 12.4 0.1 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_14 PF13173.6 EAQ87702.1 - 0.089 12.8 0.2 0.23 11.5 0.0 2.0 2 1 0 2 2 2 0 AAA domain DUF3987 PF13148.6 EAQ87702.1 - 0.1 11.6 0.0 0.37 9.8 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) Sugar_tr PF00083.24 EAQ87703.1 - 6.8e-74 249.4 17.5 8.2e-74 249.1 17.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EAQ87703.1 - 1.3e-23 83.5 26.7 5.1e-19 68.4 24.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TBP PF00352.21 EAQ87704.1 - 2.2e-58 194.2 0.1 7.5e-29 99.5 0.1 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 EAQ87704.1 - 0.00066 19.7 0.0 0.14 12.2 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) Prok_Ub PF14454.6 EAQ87704.1 - 0.064 12.9 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 Prokaryotic Ubiquitin UDPGT PF00201.18 EAQ87706.1 - 1.9e-06 26.9 0.0 2.5e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase GMC_oxred_N PF00732.19 EAQ87707.1 - 6.4e-44 150.5 0.0 2e-22 79.9 0.0 2.1 2 0 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.13 EAQ87707.1 - 2.8e-25 89.5 0.1 6e-25 88.4 0.1 1.6 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 EAQ87707.1 - 0.004 17.4 0.0 0.014 15.6 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EAQ87707.1 - 0.004 16.2 0.0 0.0069 15.5 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 EAQ87707.1 - 0.0095 15.2 0.0 0.016 14.4 0.0 1.3 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 EAQ87707.1 - 0.0098 15.5 0.1 0.024 14.2 0.1 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 EAQ87707.1 - 0.022 13.6 0.0 0.038 12.8 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_9 PF13454.6 EAQ87707.1 - 0.12 12.3 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding Methyltransf_32 PF13679.6 EAQ87707.1 - 0.22 11.5 0.0 0.37 10.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Ricin_B_lectin PF00652.22 EAQ87708.1 - 6e-11 42.7 3.9 6.3e-06 26.5 0.2 2.0 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 EAQ87708.1 - 3.1e-10 40.7 2.7 1.6e-05 25.5 0.2 2.2 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Glyco_hydro_76 PF03663.14 EAQ87710.1 - 1.4e-111 373.6 0.5 1.7e-111 373.3 0.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 EAQ87710.1 - 0.00027 20.1 1.8 0.0078 15.3 0.1 2.2 2 0 0 2 2 2 2 Glycosyl Hydrolase Family 88 Gln-synt_C PF00120.24 EAQ87711.1 - 9.7e-17 61.0 0.0 3.4e-12 46.0 0.0 2.1 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 EAQ87711.1 - 1.1e-10 41.0 0.0 1.9e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain APH PF01636.23 EAQ87712.1 - 2.5e-15 57.1 3.2 4.5e-15 56.2 3.2 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EAQ87712.1 - 0.054 13.1 0.0 0.082 12.5 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase SOG2 PF10428.9 EAQ87712.1 - 2.9 7.0 7.1 4 6.5 7.1 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein OB_NTP_bind PF07717.16 EAQ87713.1 - 1.5e-22 79.7 0.0 2.6e-22 79.0 0.0 1.4 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EAQ87713.1 - 7e-08 32.8 0.0 1.5e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Pmp3 PF01679.17 EAQ87714.1 - 7.5e-20 70.9 8.1 1e-19 70.5 8.1 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Arb1 PF09692.10 EAQ87715.1 - 1e-133 446.4 0.0 1.3e-133 446.1 0.0 1.1 1 0 0 1 1 1 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 IPK PF03770.16 EAQ87716.1 - 2e-53 181.2 0.0 6.4e-53 179.5 0.0 1.8 1 1 0 1 1 1 1 Inositol polyphosphate kinase Clp1 PF06807.14 EAQ87717.1 - 1.1e-23 83.9 0.1 1.3e-21 77.2 0.1 2.3 1 1 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 CLP1_P PF16575.5 EAQ87717.1 - 2.7e-22 79.5 0.0 3.6e-21 75.8 0.0 2.3 1 1 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop CLP1_N PF16573.5 EAQ87717.1 - 2.2e-19 69.4 0.0 1.3e-18 67.0 0.0 2.1 1 1 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor CbiA PF01656.23 EAQ87717.1 - 0.025 14.7 0.0 0.037 14.1 0.0 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_22 PF13401.6 EAQ87717.1 - 0.084 13.1 0.2 0.22 11.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 EAQ87717.1 - 0.17 12.4 0.1 0.33 11.5 0.1 1.4 1 0 0 1 1 1 0 ABC transporter Git3 PF11710.8 EAQ87718.1 - 2.1e-66 223.6 15.8 4e-66 222.6 15.8 1.5 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 GPR_Gpa2_C PF11970.8 EAQ87718.1 - 3.5e-30 103.9 2.7 1.1e-29 102.3 0.4 2.4 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term 7tm_1 PF00001.21 EAQ87718.1 - 4.2e-07 29.6 4.3 4.2e-07 29.6 4.3 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) GATase PF00117.28 EAQ87719.1 - 4e-12 46.3 0.0 5.3e-12 45.9 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 EAQ87719.1 - 0.029 14.0 0.0 0.045 13.4 0.0 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain RsfS PF02410.15 EAQ87720.1 - 3.9e-12 46.5 0.0 8.7e-12 45.3 0.0 1.6 1 1 0 1 1 1 1 Ribosomal silencing factor during starvation RNA_pol PF00940.19 EAQ87721.1 - 3.5e-185 615.7 0.0 4.9e-185 615.3 0.0 1.2 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 EAQ87721.1 - 9.9e-104 347.3 4.3 1.9e-103 346.4 4.3 1.5 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal tRNA_bind PF01588.20 EAQ87722.1 - 1.3e-22 79.7 0.1 3.1e-22 78.5 0.1 1.7 1 1 0 1 1 1 1 Putative tRNA binding domain GST_C_2 PF13410.6 EAQ87722.1 - 0.0042 17.1 0.0 0.0081 16.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain SNF2_N PF00176.23 EAQ87723.1 - 1e-59 202.1 0.1 2.1e-59 201.0 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EAQ87723.1 - 8.4e-22 77.6 0.0 3.8e-21 75.5 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EAQ87723.1 - 2.1e-07 31.1 0.7 5.6e-07 29.7 0.0 2.1 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EAQ87723.1 - 4.1e-05 22.9 0.6 0.0001 21.6 0.0 1.8 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase SWI2_SNF2 PF18766.1 EAQ87723.1 - 0.013 15.2 0.0 0.037 13.7 0.0 1.8 1 0 0 1 1 1 0 SWI2/SNF2 ATPase AAA_22 PF13401.6 EAQ87723.1 - 0.14 12.5 0.0 0.48 10.7 0.0 2.0 1 1 0 1 1 1 0 AAA domain DBINO PF13892.6 EAQ87723.1 - 0.5 10.7 11.4 1.6 9.1 11.4 1.8 1 0 0 1 1 1 0 DNA-binding domain PsbH PF00737.20 EAQ87724.1 - 0.067 12.9 1.3 0.095 12.4 0.0 1.8 2 0 0 2 2 2 0 Photosystem II 10 kDa phosphoprotein Helitron_like_N PF14214.6 EAQ87726.1 - 6.8e-39 134.1 2.5 6.8e-39 134.1 2.5 1.8 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.14 EAQ87726.1 - 2e-26 93.1 0.0 3.6e-22 79.0 0.0 2.2 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 EAQ87726.1 - 9.1e-12 45.1 0.0 2e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAQ87726.1 - 5.7e-05 23.5 0.0 0.00013 22.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 EAQ87726.1 - 0.08 12.8 0.0 0.21 11.5 0.0 1.7 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Torsin PF06309.11 EAQ87726.1 - 0.15 12.2 0.0 0.86 9.7 0.0 2.2 2 0 0 2 2 2 0 Torsin WSC PF01822.19 EAQ87727.1 - 2e-15 56.7 6.7 4.5e-15 55.6 6.7 1.6 1 0 0 1 1 1 1 WSC domain VIT1 PF01988.19 EAQ87730.1 - 3.4 7.5 7.4 5.8 6.7 7.4 1.3 1 0 0 1 1 1 0 VIT family Glyco_hydro_47 PF01532.20 EAQ87732.1 - 5.5e-173 576.1 0.0 6.3e-173 575.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_127 PF07944.12 EAQ87732.1 - 0.00066 18.3 0.0 0.033 12.7 0.0 2.3 2 1 0 2 2 2 2 Beta-L-arabinofuranosidase, GH127 zf-C2H2 PF00096.26 EAQ87733.1 - 0.38 11.3 6.4 1.3 9.7 6.4 2.0 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EAQ87733.1 - 1.1 10.2 6.4 3.6 8.7 6.4 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger Alpha_kinase PF02816.18 EAQ87735.1 - 1.6e-46 158.7 0.0 2e-46 158.5 0.0 1.1 1 0 0 1 1 1 1 Alpha-kinase family Stc1 PF12898.7 EAQ87735.1 - 0.057 14.0 2.5 0.099 13.2 2.5 1.4 1 0 0 1 1 1 0 Stc1 domain HAUS6_N PF14661.6 EAQ87736.1 - 3.1e-65 220.0 0.5 3.1e-65 220.0 0.5 2.2 2 0 0 2 2 2 1 HAUS augmin-like complex subunit 6 N-terminus PWI PF01480.17 EAQ87736.1 - 4.1e-14 52.6 0.9 8.6e-14 51.6 0.9 1.6 1 0 0 1 1 1 1 PWI domain Glyco_hydro_72 PF03198.14 EAQ87739.1 - 4e-120 400.8 4.5 5.6e-120 400.3 4.5 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 EAQ87739.1 - 1.7e-06 27.7 0.3 9.4e-06 25.3 0.3 2.0 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) zf-C2H2_6 PF13912.6 EAQ87740.1 - 0.05 13.6 0.2 0.082 12.9 0.2 1.3 1 0 0 1 1 1 0 C2H2-type zinc finger Cytochrom_B561 PF03188.16 EAQ87741.1 - 2.1e-05 24.7 8.8 4.2e-05 23.7 8.8 1.5 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 CD47 PF04549.14 EAQ87741.1 - 0.073 13.3 3.0 0.069 13.3 0.7 1.9 1 1 1 2 2 2 0 CD47 transmembrane region DUF4199 PF13858.6 EAQ87741.1 - 0.11 12.9 2.6 2.3 8.6 0.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) DUF202 PF02656.15 EAQ87741.1 - 1 9.9 10.0 3.8 8.0 0.2 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF202) Pec_lyase_C PF00544.19 EAQ87742.1 - 3.7e-40 137.8 4.8 5.2e-40 137.3 4.8 1.1 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 EAQ87742.1 - 2.7e-05 24.1 6.0 0.0003 20.7 6.0 2.3 1 1 0 1 1 1 1 Right handed beta helix region p450 PF00067.22 EAQ87743.1 - 3.1e-48 164.7 0.0 3.9e-48 164.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4812 PF16071.5 EAQ87743.1 - 0.007 16.1 0.3 0.018 14.8 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4812) APH PF01636.23 EAQ87744.1 - 5.6e-10 39.6 0.0 7.7e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EAQ87744.1 - 4.4e-09 36.2 0.0 6e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Presenilin PF01080.17 EAQ87745.1 - 8.7 5.0 6.3 14 4.3 6.3 1.2 1 0 0 1 1 1 0 Presenilin Abhydrolase_3 PF07859.13 EAQ87747.1 - 1.4e-20 74.1 1.5 1.9e-20 73.6 1.5 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EAQ87747.1 - 9.1e-05 22.0 0.0 0.032 13.7 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family AXE1 PF05448.12 EAQ87747.1 - 0.00067 18.4 0.0 0.45 9.1 0.0 2.2 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) Chlorophyllase2 PF12740.7 EAQ87747.1 - 0.0015 17.5 0.1 0.0023 16.9 0.1 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 EAQ87747.1 - 0.0036 16.4 0.1 0.0053 15.8 0.1 1.1 1 0 0 1 1 1 1 Chlorophyllase COesterase PF00135.28 EAQ87747.1 - 0.0055 15.6 0.0 0.01 14.8 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family Hydrolase_4 PF12146.8 EAQ87747.1 - 0.007 15.7 0.2 1.9 7.7 0.0 2.6 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Say1_Mug180 PF10340.9 EAQ87747.1 - 0.036 12.9 0.0 0.26 10.1 0.0 1.9 1 1 0 1 1 1 0 Steryl acetyl hydrolase Esterase PF00756.20 EAQ87747.1 - 0.14 11.8 0.1 0.94 9.1 0.1 2.1 2 0 0 2 2 2 0 Putative esterase Abhydrolase_6 PF12697.7 EAQ87748.1 - 3.7e-14 53.9 5.1 4.5e-14 53.6 5.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_8 PF06259.12 EAQ87748.1 - 0.065 12.9 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase Hydrolase_4 PF12146.8 EAQ87748.1 - 0.12 11.6 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EAQ87750.1 - 2e-15 57.1 0.6 2.6e-15 56.8 0.6 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EAQ87750.1 - 7.7e-09 36.5 20.4 7.7e-09 36.5 20.4 1.7 2 1 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EAQ87750.1 - 2.3e-06 27.1 0.2 3.5e-06 26.5 0.2 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.20 EAQ87750.1 - 4.7e-06 26.4 0.1 6.8e-06 25.9 0.1 1.3 1 0 0 1 1 1 1 Putative esterase Thioesterase PF00975.20 EAQ87750.1 - 5.4e-06 26.7 0.1 7.4e-06 26.2 0.1 1.1 1 0 0 1 1 1 1 Thioesterase domain DUF3141 PF11339.8 EAQ87750.1 - 0.06 11.8 0.6 0.082 11.3 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3141) LIP PF03583.14 EAQ87751.1 - 1.6e-55 188.4 0.0 2.2e-55 188.0 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase DUF3614 PF12267.8 EAQ87752.1 - 0.13 12.8 0.1 0.18 12.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3614) ABC_membrane PF00664.23 EAQ87755.1 - 4.8e-23 82.2 7.0 9.8e-17 61.5 0.2 4.2 4 0 0 4 4 4 3 ABC transporter transmembrane region ABC_tran PF00005.27 EAQ87755.1 - 0.02 15.4 0.0 0.039 14.5 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Polyketide_cyc2 PF10604.9 EAQ87757.1 - 3.5e-05 24.1 1.1 5.4e-05 23.5 1.1 1.3 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport DUF3464 PF11947.8 EAQ87757.1 - 0.18 11.6 0.4 0.33 10.7 0.4 1.3 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Lactamase_B_2 PF12706.7 EAQ87758.1 - 3.8e-33 114.7 0.0 4e-32 111.4 0.0 2.1 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EAQ87758.1 - 3.3e-10 40.1 0.0 5.5e-10 39.4 0.0 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EAQ87758.1 - 0.00016 21.7 2.0 0.001 19.1 0.6 2.6 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily PAS_9 PF13426.7 EAQ87759.1 - 7.6e-15 55.0 0.0 2.8e-14 53.2 0.0 1.9 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 EAQ87759.1 - 0.0028 17.6 0.0 0.007 16.4 0.0 1.6 1 0 0 1 1 1 1 PAS fold Glyco_hydro_92 PF07971.12 EAQ87760.1 - 4.7e-118 395.0 0.3 1.3e-97 327.7 0.0 3.0 1 1 2 3 3 3 3 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 EAQ87760.1 - 5.1e-58 196.8 1.1 7.7e-58 196.2 1.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain Pyrid_ox_like PF16242.5 EAQ87762.1 - 5e-23 81.3 0.0 7.6e-23 80.8 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase like Putative_PNPOx PF01243.20 EAQ87762.1 - 6.1e-08 32.7 0.0 9.5e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase TP_methylase PF00590.20 EAQ87763.1 - 3.1e-21 76.3 0.3 4.7e-21 75.7 0.3 1.3 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases zf-C2H2_jaz PF12171.8 EAQ87764.1 - 5.6e-07 29.7 0.3 9.7e-07 28.9 0.3 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EAQ87764.1 - 3.9e-06 27.1 0.4 6.6e-06 26.3 0.4 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type SNRNP27 PF08648.12 EAQ87764.1 - 0.0016 18.5 0.6 0.0059 16.6 0.6 2.0 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins zf-DBF PF07535.12 EAQ87764.1 - 0.0029 17.7 0.1 0.0057 16.7 0.1 1.4 1 0 0 1 1 1 1 DBF zinc finger Atg14 PF10186.9 EAQ87764.1 - 1.4 7.9 7.1 2.5 7.1 7.1 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Glyco_hydro_61 PF03443.14 EAQ87765.1 - 2.2e-44 151.9 0.0 3e-44 151.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.18 EAQ87765.1 - 6.1e-12 45.3 10.1 1.9e-11 43.7 10.1 1.9 1 0 0 1 1 1 1 Fungal cellulose binding domain Toxin_7 PF05980.12 EAQ87765.1 - 0.11 12.8 3.0 0.23 11.8 3.0 1.5 1 0 0 1 1 1 0 Toxin 7 UQ_con PF00179.26 EAQ87767.1 - 1.5e-36 125.1 0.0 1.8e-36 124.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EAQ87767.1 - 0.0053 16.5 0.1 0.0092 15.7 0.1 1.5 1 1 0 1 1 1 1 Prokaryotic E2 family B Glyco_trans_1_4 PF13692.6 EAQ87768.1 - 5.3e-06 26.9 0.0 1.5e-05 25.4 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Cation_efflux PF01545.21 EAQ87769.1 - 1.7e-14 54.0 0.0 2.5e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 Cation efflux family Mito_carr PF00153.27 EAQ87770.1 - 4.2e-16 58.6 0.2 7.9e-16 57.8 0.2 1.4 1 0 0 1 1 1 1 Mitochondrial carrier protein Mito_carr PF00153.27 EAQ87771.1 - 1.2e-23 82.9 1.7 4.4e-16 58.6 0.2 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein NTPase_P4 PF11602.8 EAQ87771.1 - 0.19 10.9 0.1 0.27 10.4 0.1 1.1 1 0 0 1 1 1 0 ATPase P4 of dsRNA bacteriophage phi-12 TFIIIC_delta PF12657.7 EAQ87772.1 - 4.5e-17 62.6 0.0 2.4e-16 60.2 0.0 2.2 2 1 0 2 2 2 1 Transcription factor IIIC subunit delta N-term zf-TFIIIC PF12660.7 EAQ87772.1 - 1.7e-08 34.3 0.0 4.6e-08 32.9 0.0 1.7 2 0 0 2 2 2 1 Putative zinc-finger of transcription factor IIIC complex Peptidase_C13 PF01650.18 EAQ87773.1 - 3.1e-41 141.6 0.2 4.1e-41 141.2 0.2 1.1 1 0 0 1 1 1 1 Peptidase C13 family ArgoMid PF16487.5 EAQ87773.1 - 0.071 13.4 0.0 0.19 12.0 0.0 1.7 1 0 0 1 1 1 0 Mid domain of argonaute His_Phos_1 PF00300.22 EAQ87774.1 - 3.7e-05 23.5 0.6 0.034 13.8 0.0 3.3 2 2 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) BPL_LplA_LipB_2 PF16917.5 EAQ87776.1 - 0.079 12.5 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Biotin/lipoate A/B protein ligase family F-box-like PF12937.7 EAQ87777.1 - 4.2e-09 36.2 0.9 9.2e-09 35.1 0.9 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EAQ87777.1 - 1.2e-05 25.0 0.8 2.4e-05 24.1 0.8 1.5 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 EAQ87777.1 - 0.0034 17.2 0.2 0.0062 16.4 0.2 1.4 1 0 0 1 1 1 1 F-box TetR_C_35 PF18556.1 EAQ87777.1 - 0.021 14.9 0.1 0.043 13.9 0.1 1.4 1 0 0 1 1 1 0 Bacterial Tetracyclin repressor, C-terminal domain Ribosomal_60s PF00428.19 EAQ87777.1 - 0.099 13.2 1.5 0.25 12.0 1.5 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein Acetyltransf_10 PF13673.7 EAQ87778.1 - 1.1e-06 28.5 0.0 1.9e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EAQ87778.1 - 0.00065 20.1 0.0 0.0011 19.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EAQ87778.1 - 0.011 15.9 0.0 0.025 14.8 0.0 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family FR47 PF08445.10 EAQ87778.1 - 0.024 14.6 0.0 0.047 13.7 0.0 1.5 1 1 0 1 1 1 0 FR47-like protein Dimer_Tnp_hAT PF05699.14 EAQ87779.1 - 2.7e-16 59.1 0.1 6.7e-16 57.9 0.1 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region TauD PF02668.16 EAQ87780.1 - 5.1e-39 134.7 0.1 7.1e-39 134.2 0.1 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 EAQ87780.1 - 0.0018 17.4 0.0 0.0029 16.8 0.0 1.2 1 0 0 1 1 1 1 CsiD TilS PF09179.11 EAQ87780.1 - 0.7 10.4 5.6 0.27 11.7 2.4 2.0 2 0 0 2 2 2 0 TilS substrate binding domain TFIIA PF03153.13 EAQ87782.1 - 0.75 9.7 17.7 0.78 9.7 17.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SPX PF03105.19 EAQ87782.1 - 6.7 6.5 18.2 8.5 6.2 18.2 1.1 1 0 0 1 1 1 0 SPX domain Pkinase PF00069.25 EAQ87783.1 - 5e-09 35.9 0.0 6.8e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Choline_kinase PF01633.20 EAQ87783.1 - 7.3e-05 22.4 0.1 0.00016 21.3 0.1 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 EAQ87783.1 - 0.0028 17.6 0.1 0.0053 16.7 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EAQ87783.1 - 0.052 12.9 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Rhodanese PF00581.20 EAQ87786.1 - 7.6e-15 55.3 0.0 9.7e-15 55.0 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain LapA_dom PF06305.11 EAQ87787.1 - 0.00086 19.1 0.1 0.0012 18.6 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide assembly protein A domain TMEM51 PF15345.6 EAQ87787.1 - 0.011 15.5 0.0 0.016 15.1 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 CD34_antigen PF06365.12 EAQ87787.1 - 0.15 11.6 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family EphA2_TM PF14575.6 EAQ87787.1 - 0.17 12.8 0.0 0.28 12.1 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain UPF0121 PF03661.13 EAQ87788.1 - 3.8e-28 98.5 2.6 5.4e-28 98.0 2.6 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) Pribosyl_synth PF14572.6 EAQ87791.1 - 1.6e-35 122.8 2.6 6.3e-31 107.8 1.1 2.2 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 EAQ87791.1 - 3.4e-32 110.8 0.2 1e-31 109.3 0.0 1.9 2 1 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 EAQ87791.1 - 2.7e-14 53.0 0.8 4.5e-14 52.3 0.2 1.6 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EAQ87791.1 - 0.003 17.0 0.3 0.0064 16.0 0.3 1.5 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AF2331-like PF14556.6 EAQ87791.1 - 0.1 13.2 0.7 8.5 7.0 0.0 3.0 3 0 0 3 3 3 0 AF2331-like DPBB_1 PF03330.18 EAQ87791.1 - 0.11 12.8 0.0 0.94 9.8 0.0 2.4 3 0 0 3 3 3 0 Lytic transglycolase GRP PF07172.11 EAQ87792.1 - 3.9 8.2 19.7 66 4.3 0.0 2.1 2 0 0 2 2 2 0 Glycine rich protein family Pkinase PF00069.25 EAQ87796.1 - 4.9e-71 239.2 0.0 7.7e-71 238.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ87796.1 - 4.4e-34 117.9 0.0 6.1e-34 117.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 EAQ87796.1 - 6.9e-12 45.9 1.6 2.2e-11 44.3 1.6 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 EAQ87796.1 - 3.4e-06 26.3 0.1 5e-06 25.7 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain C2 PF00168.30 EAQ87796.1 - 0.0034 17.6 0.0 0.0075 16.5 0.0 1.5 1 0 0 1 1 1 1 C2 domain Kinase-like PF14531.6 EAQ87796.1 - 0.0077 15.6 0.0 0.015 14.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 EAQ87796.1 - 0.072 12.7 0.1 0.84 9.2 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 EAQ87796.1 - 0.13 11.6 0.2 0.3 10.4 0.1 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family PGI PF00342.19 EAQ87797.1 - 1.1e-226 753.2 0.6 1.2e-226 753.0 0.6 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase CUE PF02845.16 EAQ87798.1 - 6.9e-09 35.2 0.0 1.1e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 CUE domain Kelch_5 PF13854.6 EAQ87800.1 - 1.9e-13 50.0 10.3 2.5e-07 30.5 0.1 4.1 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.6 EAQ87800.1 - 5.9e-10 39.2 11.1 0.00046 20.4 0.1 5.3 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_4 PF13418.6 EAQ87800.1 - 1.4e-09 37.8 7.6 0.15 12.1 0.1 4.8 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_6 PF13964.6 EAQ87800.1 - 5.8e-08 32.7 9.5 0.0099 16.1 0.4 4.4 4 0 0 4 4 4 3 Kelch motif Kelch_1 PF01344.25 EAQ87800.1 - 3.7e-07 29.6 3.9 0.11 12.1 0.1 4.2 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.15 EAQ87800.1 - 0.0005 19.9 3.3 0.052 13.6 0.1 3.7 3 0 0 3 3 3 1 Kelch motif Gly_transf_sug PF04488.15 EAQ87801.1 - 3.5e-09 37.2 0.0 6e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 EAQ87801.1 - 0.012 15.1 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein SKG6 PF08693.10 EAQ87802.1 - 3.2e-06 26.4 0.2 5.3e-06 25.7 0.2 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain MGC-24 PF05283.11 EAQ87802.1 - 0.12 12.8 3.1 0.17 12.3 3.1 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin PIF1 PF05970.14 EAQ87803.1 - 2.8e-32 112.3 0.0 5.2e-28 98.2 0.0 2.4 2 1 0 2 2 2 2 PIF1-like helicase Helitron_like_N PF14214.6 EAQ87803.1 - 4.9e-24 85.6 1.8 4.6e-20 72.6 0.2 2.4 1 1 1 2 2 2 2 Helitron helicase-like domain at N-terminus AAA_30 PF13604.6 EAQ87803.1 - 2.1e-10 40.7 0.0 4.3e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAQ87803.1 - 7.2e-07 29.6 0.0 1.5e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 EAQ87803.1 - 1.6e-05 24.6 0.0 4.1e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.14 EAQ87803.1 - 0.00051 18.1 0.0 0.00092 17.3 0.0 1.3 1 0 0 1 1 1 1 Helicase Viral_helicase1 PF01443.18 EAQ87803.1 - 0.028 14.2 0.1 3 7.5 0.1 2.6 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Nif11 PF07862.11 EAQ87803.1 - 0.037 14.3 0.1 0.1 12.9 0.1 1.8 1 0 0 1 1 1 0 Nif11 domain Torsin PF06309.11 EAQ87803.1 - 0.12 12.5 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 Torsin AAA_11 PF13086.6 EAQ87803.1 - 0.14 11.9 0.0 26 4.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain NmrA PF05368.13 EAQ87804.1 - 2.2e-05 24.1 0.0 4.7e-05 23.1 0.0 1.6 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EAQ87804.1 - 0.0079 16.1 0.0 0.016 15.1 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding RVT_1 PF00078.27 EAQ87806.1 - 3.9e-06 26.5 0.0 6.1e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HSP70 PF00012.20 EAQ87807.1 - 3.6e-06 25.5 0.0 0.0037 15.5 0.0 2.1 2 0 0 2 2 2 2 Hsp70 protein SnoaL_4 PF13577.6 EAQ87808.1 - 3.7e-15 56.2 0.2 4.5e-15 55.9 0.2 1.0 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_2 PF12680.7 EAQ87808.1 - 0.0046 17.6 0.0 0.0077 16.9 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 EAQ87808.1 - 0.057 13.2 0.0 0.095 12.5 0.0 1.3 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase p450 PF00067.22 EAQ87809.1 - 6.4e-36 124.1 0.0 9.7e-36 123.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 SUV3_C PF12513.8 EAQ87809.1 - 0.23 11.4 0.3 14 5.7 0.0 2.6 2 1 0 2 2 2 0 Mitochondrial degradasome RNA helicase subunit C terminal 3HCDH_N PF02737.18 EAQ87810.1 - 4e-25 88.7 0.0 1.6e-24 86.8 0.0 1.9 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 EAQ87810.1 - 9.5e-15 55.0 0.0 1.6e-14 54.3 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 2-Hacid_dh_C PF02826.19 EAQ87810.1 - 0.00083 18.8 0.0 0.0013 18.1 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 EAQ87810.1 - 0.0046 16.2 0.0 0.0068 15.7 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EAQ87810.1 - 0.01 16.3 0.0 0.019 15.5 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.23 EAQ87810.1 - 0.039 13.9 0.0 0.061 13.3 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus TrkA_N PF02254.18 EAQ87810.1 - 0.047 13.9 0.0 0.084 13.1 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_2 PF03446.15 EAQ87810.1 - 0.055 13.6 0.0 0.28 11.3 0.0 2.0 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_7 PF13241.6 EAQ87810.1 - 0.2 12.1 0.0 0.42 11.1 0.0 1.5 2 0 0 2 2 2 0 Putative NAD(P)-binding SLATT_fungal PF18142.1 EAQ87811.1 - 6e-23 81.1 0.1 1.4e-22 79.9 0.1 1.5 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain PHD PF00628.29 EAQ87812.1 - 0.00012 21.9 8.2 0.00019 21.2 8.2 1.3 1 0 0 1 1 1 1 PHD-finger DUF3973 PF13119.6 EAQ87812.1 - 0.021 14.9 0.7 0.039 14.0 0.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3973) C1_1 PF00130.22 EAQ87812.1 - 0.12 12.3 8.4 0.19 11.6 8.4 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) CoA_transf_3 PF02515.17 EAQ87813.1 - 8.4e-118 393.7 0.0 9.5e-118 393.5 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III SF3A2 PF16835.5 EAQ87814.1 - 5.1e-35 119.7 0.0 7.7e-35 119.1 0.0 1.3 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 EAQ87814.1 - 4.7e-06 26.8 1.5 7.2e-06 26.2 0.9 1.7 2 0 0 2 2 2 1 Zinc-finger of C2H2 type CactinC_cactus PF09732.9 EAQ87814.1 - 8.4e-05 22.5 0.1 0.00012 22.0 0.1 1.2 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein NAD_binding_1 PF00175.21 EAQ87814.1 - 0.033 14.8 0.1 0.095 13.3 0.0 1.7 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain PRP4 PF08799.11 EAQ87814.1 - 0.068 12.7 1.5 0.12 12.0 1.5 1.4 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like Pkinase PF00069.25 EAQ87815.1 - 4.3e-58 196.8 0.0 7.9e-57 192.6 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ87815.1 - 2e-26 92.8 0.3 2.9e-20 72.7 0.1 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 EAQ87815.1 - 3.9e-05 22.8 0.1 9.1e-05 21.6 0.1 1.5 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EAQ87815.1 - 0.00077 18.9 0.0 0.0017 17.7 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EAQ87815.1 - 0.00086 19.3 1.8 0.021 14.8 0.3 2.5 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EAQ87815.1 - 0.0012 18.2 0.0 0.0012 18.2 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.11 EAQ87815.1 - 0.066 12.3 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 FTA2 PF13095.6 EAQ87815.1 - 0.12 11.9 0.5 12 5.5 0.0 2.5 2 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 EAQ87815.1 - 0.35 10.4 2.8 0.68 9.5 0.1 2.1 2 0 0 2 2 2 0 RIO1 family Tim54 PF11711.8 EAQ87816.1 - 2.8e-142 474.0 0.8 3.3e-142 473.7 0.8 1.1 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 DUF3408 PF11888.8 EAQ87816.1 - 0.062 13.4 0.7 0.062 13.4 0.7 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3408) DUF346 PF03984.13 EAQ87817.1 - 0.29 10.9 0.1 0.29 10.9 0.1 7.1 8 0 0 8 8 8 0 Repeat of unknown function (DUF346) Cyclin PF08613.11 EAQ87818.1 - 1.9e-10 41.4 0.0 3.2e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Cyclin RSN1_7TM PF02714.15 EAQ87818.1 - 0.0023 17.3 0.0 0.0036 16.6 0.0 1.3 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate Cyclin_N PF00134.23 EAQ87818.1 - 0.012 15.4 0.0 0.018 14.8 0.0 1.2 1 0 0 1 1 1 0 Cyclin, N-terminal domain ANAPC16 PF17256.2 EAQ87818.1 - 0.046 14.1 0.1 24 5.4 0.0 3.1 2 1 1 3 3 3 0 Anaphase-promoting complex, subunit 16 zf-HC3 PF16827.5 EAQ87819.1 - 0.12 12.6 2.7 0.29 11.4 2.2 1.9 1 1 1 2 2 2 0 zinc-finger CRC_subunit PF08624.10 EAQ87820.1 - 9.5e-54 181.5 0.0 1.5e-53 180.9 0.0 1.3 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit DUF4746 PF15928.5 EAQ87820.1 - 1.4 8.3 10.6 3 7.2 10.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) CDC45 PF02724.14 EAQ87820.1 - 5.8 5.1 6.0 8.3 4.6 6.0 1.2 1 0 0 1 1 1 0 CDC45-like protein TFIIB PF00382.19 EAQ87821.1 - 5.2e-35 119.3 1.9 5.9e-19 67.9 0.2 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 EAQ87821.1 - 1.2e-12 47.1 1.7 2e-12 46.4 1.7 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_C PF02984.19 EAQ87821.1 - 1.6e-05 25.0 0.0 0.092 12.8 0.0 2.3 2 0 0 2 2 2 2 Cyclin, C-terminal domain OSTMP1 PF09777.9 EAQ87821.1 - 0.0064 15.9 0.0 0.015 14.7 0.0 1.5 1 0 0 1 1 1 1 Osteopetrosis-associated transmembrane protein 1 precursor RB_B PF01857.20 EAQ87821.1 - 0.021 14.8 0.0 0.042 13.9 0.0 1.6 1 0 0 1 1 1 0 Retinoblastoma-associated protein B domain PhnA_Zn_Ribbon PF08274.12 EAQ87821.1 - 0.032 14.2 1.8 1.4 9.0 0.2 2.3 2 0 0 2 2 2 0 PhnA Zinc-Ribbon Cyclin_N PF00134.23 EAQ87821.1 - 0.067 12.9 0.1 1.2 8.9 0.0 2.2 2 0 0 2 2 2 0 Cyclin, N-terminal domain zf-ribbon_3 PF13248.6 EAQ87821.1 - 0.32 10.5 2.9 4.9 6.7 2.9 2.3 1 1 0 1 1 1 0 zinc-ribbon domain MASE1 PF05231.14 EAQ87822.1 - 0.041 13.0 0.0 0.06 12.5 0.0 1.1 1 0 0 1 1 1 0 MASE1 Seryl_tRNA_N PF02403.22 EAQ87822.1 - 0.041 14.1 4.0 0.067 13.4 4.0 1.3 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain BCLP PF12304.8 EAQ87822.1 - 0.053 13.1 0.1 0.083 12.4 0.1 1.2 1 0 0 1 1 1 0 Beta-casein like protein EphA2_TM PF14575.6 EAQ87822.1 - 0.18 12.7 0.1 0.29 12.0 0.1 1.5 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain LapA_dom PF06305.11 EAQ87822.1 - 0.28 11.0 1.0 0.41 10.5 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Asn_synthase PF00733.21 EAQ87824.1 - 1.7e-16 60.8 0.4 8.7e-08 32.2 0.1 3.1 2 1 1 3 3 3 3 Asparagine synthase GATase_7 PF13537.6 EAQ87824.1 - 7.5e-08 32.3 0.0 3.7e-07 30.1 0.0 2.1 3 0 0 3 3 3 1 Glutamine amidotransferase domain GATase_6 PF13522.6 EAQ87824.1 - 0.00012 22.2 0.0 0.00027 21.1 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 EAQ87824.1 - 0.0013 18.2 0.0 0.0023 17.4 0.0 1.2 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 EAQ87824.1 - 0.035 13.2 0.0 0.14 11.3 0.0 1.8 2 0 0 2 2 2 0 NAD synthase VPS9 PF02204.18 EAQ87825.1 - 3.5e-16 59.3 0.0 7.1e-16 58.3 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain CUE PF02845.16 EAQ87825.1 - 3.7e-09 36.1 0.2 1.6e-07 30.8 0.0 2.4 2 0 0 2 2 2 1 CUE domain DUF5601 PF18151.1 EAQ87825.1 - 5.3e-08 33.1 0.0 1.2e-07 31.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5601) zf-RVT PF13966.6 EAQ87826.1 - 0.013 16.2 0.1 0.013 16.2 0.1 2.3 3 0 0 3 3 3 0 zinc-binding in reverse transcriptase DUF2076 PF09849.9 EAQ87827.1 - 0.011 15.7 9.4 0.014 15.4 9.4 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Cyt-b5 PF00173.28 EAQ87828.1 - 7.5e-14 51.6 0.0 1e-13 51.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain GMC_oxred_N PF00732.19 EAQ87829.1 - 4.5e-60 203.5 0.0 5.9e-60 203.1 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EAQ87829.1 - 2.9e-28 99.2 0.2 7.8e-28 97.8 0.2 1.8 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 EAQ87829.1 - 1.7e-06 28.1 0.1 5.5e-06 26.5 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EAQ87829.1 - 1.5e-05 24.3 0.2 3.1e-05 23.2 0.2 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 EAQ87829.1 - 3.3e-05 23.2 4.4 0.00067 18.8 4.4 2.3 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 EAQ87829.1 - 6e-05 22.8 1.9 0.00037 20.2 1.9 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EAQ87829.1 - 0.00048 19.5 0.1 0.0019 17.5 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EAQ87829.1 - 0.00077 18.8 0.3 0.15 11.3 0.2 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EAQ87829.1 - 0.00091 18.5 0.2 0.003 16.8 0.1 1.8 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 EAQ87829.1 - 0.0026 17.1 0.0 0.0057 15.9 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 EAQ87829.1 - 0.0057 15.4 0.1 0.0088 14.8 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein TrkA_N PF02254.18 EAQ87829.1 - 0.0088 16.3 0.0 0.068 13.4 0.0 2.3 2 0 0 2 2 2 1 TrkA-N domain Trp_halogenase PF04820.14 EAQ87829.1 - 0.038 12.8 0.2 0.056 12.3 0.2 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox PF00070.27 EAQ87829.1 - 0.056 14.0 0.1 0.14 12.7 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EAQ87829.1 - 0.13 12.3 0.2 0.33 10.9 0.2 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding PIF1 PF05970.14 EAQ87830.1 - 2.9e-32 112.2 0.0 5.3e-28 98.2 0.0 2.4 2 1 0 2 2 2 2 PIF1-like helicase Helitron_like_N PF14214.6 EAQ87830.1 - 2e-25 90.1 0.4 3.9e-25 89.2 0.4 1.4 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus AAA_30 PF13604.6 EAQ87830.1 - 2.1e-10 40.6 0.0 4.4e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAQ87830.1 - 7.2e-07 29.6 0.0 1.5e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 EAQ87830.1 - 1.6e-05 24.6 0.0 4.2e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.14 EAQ87830.1 - 0.00052 18.1 0.0 0.00093 17.3 0.0 1.3 1 0 0 1 1 1 1 Helicase Viral_helicase1 PF01443.18 EAQ87830.1 - 0.029 14.1 0.1 3 7.5 0.1 2.6 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Nif11 PF07862.11 EAQ87830.1 - 0.037 14.3 0.1 0.1 12.9 0.1 1.8 1 0 0 1 1 1 0 Nif11 domain Torsin PF06309.11 EAQ87830.1 - 0.12 12.4 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Torsin AAA_11 PF13086.6 EAQ87830.1 - 0.15 11.9 0.0 26 4.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain TIM PF00121.18 EAQ87831.1 - 1.8e-42 145.4 0.0 4.3e-42 144.2 0.0 1.6 1 1 0 1 1 1 1 Triosephosphate isomerase Cid2 PF09774.9 EAQ87831.1 - 0.2 12.1 0.2 0.32 11.4 0.2 1.3 1 0 0 1 1 1 0 Caffeine-induced death protein 2 LacAB_rpiB PF02502.18 EAQ87832.1 - 4.4e-43 146.6 0.7 5e-43 146.4 0.7 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase Arm-DNA-bind_3 PF13356.6 EAQ87832.1 - 0.13 12.6 0.0 0.24 11.8 0.0 1.6 1 1 0 1 1 1 0 Arm DNA-binding domain Dak1 PF02733.17 EAQ87833.1 - 1.9e-101 339.1 0.0 2.7e-101 338.6 0.0 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 EAQ87833.1 - 7.3e-39 133.4 5.3 1.4e-38 132.5 5.3 1.5 1 0 0 1 1 1 1 DAK2 domain F_bP_aldolase PF01116.20 EAQ87834.1 - 7.2e-88 294.7 0.3 8.1e-88 294.5 0.3 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II NAD_binding_11 PF14833.6 EAQ87835.1 - 8.5e-38 129.3 5.0 4.8e-27 94.6 0.2 2.5 2 0 0 2 2 2 2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.15 EAQ87835.1 - 1.5e-32 113.0 0.3 2.9e-32 112.0 0.3 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Pre-SET PF05033.16 EAQ87835.1 - 7.2e-18 65.2 4.0 7.2e-18 65.2 4.0 2.5 3 0 0 3 3 3 1 Pre-SET motif SET PF00856.28 EAQ87835.1 - 8.1e-18 65.4 0.1 2.5e-16 60.5 0.0 2.9 2 1 0 2 2 2 1 SET domain F420_oxidored PF03807.17 EAQ87835.1 - 0.0022 18.5 0.1 0.007 16.9 0.0 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 EAQ87835.1 - 0.0028 17.6 0.3 0.0079 16.1 0.3 1.8 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 EAQ87835.1 - 0.02 14.5 0.2 0.056 13.1 0.0 1.8 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA UBD PF16455.5 EAQ87836.1 - 2.8e-37 127.1 0.1 5.7e-37 126.1 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-binding domain Gly_transf_sug PF04488.15 EAQ87837.1 - 2.1e-14 53.9 0.0 3.8e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 EAQ87837.1 - 0.0075 15.6 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 TcdA/TcdB catalytic glycosyltransferase domain DctQ PF04290.12 EAQ87837.1 - 0.044 13.7 0.5 0.1 12.5 0.1 1.7 2 0 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component Caps_synth PF05704.12 EAQ87837.1 - 0.1 11.9 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein Cucumo_coat PF00760.18 EAQ87837.1 - 0.11 12.1 1.6 0.2 11.3 1.6 1.5 1 0 0 1 1 1 0 Cucumovirus coat protein Mucin PF01456.17 EAQ87837.1 - 0.46 10.5 15.0 0.83 9.6 15.0 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF4834 PF16118.5 EAQ87837.1 - 1.6 9.7 4.5 7.1 7.7 4.5 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) Peptidase_M20 PF01546.28 EAQ87838.1 - 1.1e-15 57.9 0.0 1.5e-15 57.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 PG_binding_2 PF08823.11 EAQ87838.1 - 0.014 15.7 0.0 0.037 14.3 0.0 1.7 1 0 0 1 1 1 0 Putative peptidoglycan binding domain adh_short PF00106.25 EAQ87839.1 - 6.7e-15 55.1 0.0 9.3e-15 54.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EAQ87839.1 - 9.9e-11 41.6 0.0 1.3e-10 41.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 EAQ87839.1 - 0.00038 20.0 0.0 0.00052 19.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EAQ87839.1 - 0.0012 18.8 0.0 0.002 18.0 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Adaptin_N PF01602.20 EAQ87840.1 - 1.3e-92 311.1 5.3 2.4e-92 310.2 5.3 1.3 1 0 0 1 1 1 1 Adaptin N terminal region Coatamer_beta_C PF07718.12 EAQ87840.1 - 2e-58 196.3 0.3 4.2e-58 195.2 0.3 1.6 1 0 0 1 1 1 1 Coatomer beta C-terminal region Coatomer_b_Cpla PF14806.6 EAQ87840.1 - 5.2e-56 188.1 0.0 1.4e-55 186.7 0.0 1.7 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Cnd1 PF12717.7 EAQ87840.1 - 8.6e-14 51.9 3.3 9.3e-10 38.8 0.0 3.5 2 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EAQ87840.1 - 8.6e-07 29.3 7.6 0.0068 16.8 0.0 5.4 3 1 2 6 6 6 3 HEAT repeats Coatomer_g_Cpla PF16381.5 EAQ87840.1 - 0.00017 21.7 0.0 0.00059 20.0 0.0 2.0 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT PF02985.22 EAQ87840.1 - 0.0004 20.4 0.3 7.1 7.2 0.0 4.8 4 0 0 4 4 4 1 HEAT repeat DUF5578 PF17741.1 EAQ87840.1 - 0.015 14.7 3.1 3.2 7.1 0.9 2.7 2 1 0 2 2 2 0 Family of unknown function (DUF5578) AP4E_app_platf PF14807.6 EAQ87840.1 - 0.036 14.4 0.1 0.12 12.8 0.1 1.9 1 0 0 1 1 1 0 Adaptin AP4 complex epsilon appendage platform HEAT_EZ PF13513.6 EAQ87840.1 - 0.14 12.7 1.6 19 5.9 0.0 3.9 4 0 0 4 4 4 0 HEAT-like repeat Mago_nashi PF02792.14 EAQ87841.1 - 2.5e-72 241.6 0.3 2.8e-72 241.4 0.3 1.0 1 0 0 1 1 1 1 Mago nashi protein Vac_ImportDeg PF09783.9 EAQ87842.1 - 4.1e-63 212.0 3.6 5e-63 211.7 3.6 1.1 1 0 0 1 1 1 1 Vacuolar import and degradation protein UPF0020 PF01170.18 EAQ87843.1 - 0.00013 21.7 0.0 0.0002 21.1 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Ribonuc_P_40 PF08584.11 EAQ87844.1 - 9.3e-39 133.4 0.0 1.1e-38 133.1 0.0 1.0 1 0 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit EF_assoc_1 PF08355.12 EAQ87844.1 - 0.08 12.5 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 EF hand associated Ank_5 PF13857.6 EAQ87845.1 - 1.3e-10 41.3 0.0 8.2e-07 29.2 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAQ87845.1 - 2.4e-06 28.0 0.0 0.00038 21.0 0.0 2.6 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAQ87845.1 - 0.0015 19.1 0.0 0.0026 18.3 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAQ87845.1 - 0.089 13.4 0.3 0.72 10.6 0.0 2.6 3 1 0 3 3 3 0 Ankyrin repeat RNA_lig_T4_1 PF09511.10 EAQ87846.1 - 9.3e-87 290.5 0.0 1.6e-86 289.7 0.0 1.4 1 0 0 1 1 1 1 RNA ligase tRNA_lig_CPD PF08302.11 EAQ87846.1 - 8e-78 261.4 0.0 1.3e-77 260.7 0.0 1.3 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain tRNA_lig_kinase PF08303.11 EAQ87846.1 - 1.7e-56 190.9 0.1 3.2e-56 190.0 0.1 1.5 1 0 0 1 1 1 1 tRNA ligase kinase domain Glycos_transf_3 PF00591.21 EAQ87847.1 - 5.5e-59 199.8 0.0 2.2e-58 197.8 0.0 1.9 1 1 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 EAQ87847.1 - 3.9e-12 45.8 0.0 1e-11 44.5 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferase family, helical bundle domain AAA PF00004.29 EAQ87850.1 - 5.1e-41 140.2 0.0 8.2e-41 139.5 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EAQ87850.1 - 5.8e-06 26.3 0.1 3.4e-05 23.9 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EAQ87850.1 - 8.5e-06 26.3 0.1 0.0055 17.1 0.0 2.3 1 1 1 2 2 2 2 AAA ATPase domain RuvB_N PF05496.12 EAQ87850.1 - 7e-05 22.6 0.0 0.00022 21.0 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EAQ87850.1 - 9.6e-05 22.7 0.3 0.028 14.7 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.14 EAQ87850.1 - 0.00033 20.8 0.0 0.0019 18.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) PhoH PF02562.16 EAQ87850.1 - 0.0015 18.0 0.3 0.028 13.9 0.1 2.1 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.21 EAQ87850.1 - 0.0039 16.6 0.1 0.0084 15.5 0.0 1.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 EAQ87850.1 - 0.0062 16.7 0.0 0.0088 16.2 0.0 1.5 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 EAQ87850.1 - 0.018 14.2 0.0 0.022 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 EAQ87850.1 - 0.026 14.3 0.1 0.059 13.1 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_7 PF12775.7 EAQ87850.1 - 0.035 13.6 0.0 0.096 12.2 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 EAQ87850.1 - 0.041 13.6 0.1 0.082 12.6 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAQ87850.1 - 0.058 13.0 0.8 0.56 9.7 0.2 2.1 1 1 1 2 2 2 0 AAA domain ATPase PF06745.13 EAQ87850.1 - 0.064 12.6 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA_11 PF13086.6 EAQ87850.1 - 0.11 12.3 0.0 0.14 11.9 0.0 1.4 1 1 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 EAQ87850.1 - 0.12 12.1 0.0 0.36 10.5 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain Clr5 PF14420.6 EAQ87851.1 - 5.7e-11 42.5 1.8 1.1e-10 41.6 1.8 1.5 1 1 0 1 1 1 1 Clr5 domain Ish1 PF10281.9 EAQ87852.1 - 4.3e-60 199.7 10.7 5.6e-14 52.2 0.0 6.8 7 1 0 7 7 7 6 Putative stress-responsive nuclear envelope protein SAP PF02037.27 EAQ87852.1 - 6e-06 25.9 0.0 0.073 12.8 0.0 3.9 5 0 0 5 5 5 2 SAP domain ApoO PF09769.9 EAQ87852.1 - 0.0036 17.3 2.5 0.15 12.1 0.1 3.2 3 0 0 3 3 3 1 Apolipoprotein O HeH PF12949.7 EAQ87852.1 - 0.0055 16.4 0.0 1.1 9.0 0.0 3.7 4 0 0 4 4 4 1 HeH/LEM domain Slx4 PF09494.10 EAQ87852.1 - 0.025 14.5 0.3 7 6.7 0.0 3.4 3 1 1 4 4 4 0 Slx4 endonuclease YtxH PF12732.7 EAQ87852.1 - 0.17 12.5 11.2 9.6 6.8 0.2 4.2 3 1 0 3 3 3 0 YtxH-like protein SLATT_4 PF18186.1 EAQ87852.1 - 1.8 8.2 7.9 2.8 7.5 0.6 3.1 3 0 0 3 3 3 0 SMODS and SLOG-associating 2TM effector domain family 4 Glyco_hydro_61 PF03443.14 EAQ87854.1 - 1.6e-47 162.1 0.1 1.9e-47 161.8 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF5324 PF17258.2 EAQ87854.1 - 0.19 11.4 0.0 0.28 10.8 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5324) AMP-binding PF00501.28 EAQ87855.1 - 2.7e-38 131.7 0.0 2.8e-24 85.5 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 EAQ87855.1 - 5.9e-18 65.6 0.0 1.1e-17 64.8 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ketoacyl-synt PF00109.26 EAQ87856.1 - 7.9e-59 199.3 0.0 1.7e-58 198.2 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 EAQ87856.1 - 3.1e-58 196.6 0.2 1.1e-57 194.9 0.2 2.0 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.21 EAQ87856.1 - 1.5e-42 146.3 0.3 1.5e-42 146.3 0.3 1.6 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EAQ87856.1 - 2.2e-38 130.9 0.1 5.2e-38 129.7 0.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.6 EAQ87856.1 - 6.6e-33 114.2 0.6 1.4e-32 113.1 0.6 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase ADH_zinc_N_2 PF13602.6 EAQ87856.1 - 5.2e-22 79.3 0.0 6.1e-21 75.9 0.0 3.0 3 0 0 3 3 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EAQ87856.1 - 1.7e-19 70.1 0.4 8.1e-19 67.9 0.1 2.4 2 0 0 2 2 2 1 Zinc-binding dehydrogenase KAsynt_C_assoc PF16197.5 EAQ87856.1 - 1.6e-15 57.5 0.0 5.4e-15 55.8 0.0 1.9 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_12 PF08242.12 EAQ87856.1 - 6.8e-14 52.4 0.0 2e-13 50.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAQ87856.1 - 2.1e-09 38.0 0.0 9.5e-09 35.9 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 EAQ87856.1 - 3.7e-09 36.3 0.1 1.4e-08 34.4 0.1 2.0 1 0 0 1 1 1 1 short chain dehydrogenase PP-binding PF00550.25 EAQ87856.1 - 1.5e-06 28.4 0.0 4.8e-06 26.8 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_11 PF08241.12 EAQ87856.1 - 1.6e-06 28.6 0.0 6.5e-06 26.7 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAQ87856.1 - 1.4e-05 24.9 0.0 3e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain SAT PF16073.5 EAQ87856.1 - 8.6e-05 22.4 0.7 0.00025 20.9 0.7 1.8 1 1 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Methyltransf_23 PF13489.6 EAQ87856.1 - 0.00044 20.1 0.0 0.0011 18.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 EAQ87856.1 - 0.0018 18.1 0.0 0.006 16.3 0.0 1.8 2 0 0 2 2 2 1 Lysine methyltransferase PCMT PF01135.19 EAQ87856.1 - 0.0043 16.8 0.0 0.021 14.6 0.0 2.0 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Thiolase_N PF00108.23 EAQ87856.1 - 0.009 15.4 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain AlaDh_PNT_C PF01262.21 EAQ87856.1 - 0.01 15.2 0.1 0.022 14.1 0.1 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Transferase PF02458.15 EAQ87857.1 - 3.7e-26 91.8 0.0 3e-25 88.8 0.0 2.2 1 1 0 1 1 1 1 Transferase family AMP-binding PF00501.28 EAQ87858.1 - 1.2e-163 544.7 0.0 2.6e-83 280.0 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.20 EAQ87858.1 - 3.2e-114 382.1 0.0 4.6e-32 111.3 0.0 6.3 5 1 1 6 6 6 6 Condensation domain PP-binding PF00550.25 EAQ87858.1 - 3e-47 158.8 0.2 2.9e-11 43.5 0.1 5.0 4 0 0 4 4 4 4 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EAQ87858.1 - 1.9e-07 32.0 0.0 0.0076 17.2 0.0 3.2 3 0 0 3 3 3 2 AMP-binding enzyme C-terminal domain DIOX_N PF14226.6 EAQ87859.1 - 1.5e-14 54.8 0.0 2.3e-14 54.2 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EAQ87859.1 - 5.2e-14 52.6 0.0 1.6e-13 51.0 0.0 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Annexin PF00191.20 EAQ87860.1 - 5.7e-68 224.9 2.7 1.3e-18 66.8 0.2 4.2 4 0 0 4 4 4 4 Annexin DUF3574 PF12098.8 EAQ87860.1 - 0.25 11.1 0.3 15 5.4 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3574) ACT PF01842.25 EAQ87863.1 - 0.012 15.4 0.0 0.033 14.0 0.0 1.7 1 0 0 1 1 1 0 ACT domain HLH PF00010.26 EAQ87863.1 - 0.13 12.2 0.9 0.27 11.2 0.9 1.5 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain EHN PF06441.12 EAQ87864.1 - 3.7e-27 94.8 0.1 5.4e-27 94.3 0.1 1.3 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 EAQ87864.1 - 0.0094 15.6 0.3 0.018 14.7 0.3 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Git3 PF11710.8 EAQ87865.1 - 1.5e-15 57.5 4.9 3.7e-15 56.3 4.9 1.6 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.21 EAQ87865.1 - 6.8e-08 32.1 5.5 1e-07 31.6 3.4 1.9 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) Dicty_CAR PF05462.11 EAQ87865.1 - 0.0003 20.0 7.6 0.00048 19.3 7.6 1.2 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor Cadherin_C_2 PF16492.5 EAQ87865.1 - 0.03 15.1 0.0 12 6.7 0.0 2.6 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal GPR_Gpa2_C PF11970.8 EAQ87865.1 - 0.042 13.9 0.2 0.042 13.9 0.2 2.1 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 C-term Pex2_Pex12 PF04757.14 EAQ87865.1 - 0.13 11.8 1.0 0.2 11.2 0.0 1.6 2 0 0 2 2 2 0 Pex2 / Pex12 amino terminal region Aldo_ket_red PF00248.21 EAQ87867.1 - 4.3e-42 144.3 0.0 4.8e-42 144.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family CDO_I PF05995.12 EAQ87868.1 - 5.9e-42 142.8 0.0 9.1e-42 142.2 0.0 1.2 1 0 0 1 1 1 1 Cysteine dioxygenase type I PCO_ADO PF07847.12 EAQ87868.1 - 0.0032 16.9 0.0 0.0048 16.4 0.0 1.3 1 0 0 1 1 1 1 PCO_ADO Voltage_CLC PF00654.20 EAQ87869.1 - 1.7e-88 297.3 27.0 1.7e-88 297.3 27.0 1.5 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 EAQ87869.1 - 9.3e-12 45.2 0.1 0.00013 22.4 0.0 2.7 2 0 0 2 2 2 2 CBS domain CBFD_NFYB_HMF PF00808.23 EAQ87870.1 - 2.7e-10 40.4 0.1 5.4e-10 39.4 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone LRR_9 PF14580.6 EAQ87871.1 - 7.9e-55 185.0 0.1 1.3e-54 184.3 0.0 1.4 2 0 0 2 2 2 1 Leucine-rich repeat LRR_8 PF13855.6 EAQ87871.1 - 3.5e-07 29.9 0.2 3.5e-07 29.9 0.2 3.0 4 0 0 4 4 4 1 Leucine rich repeat LRR_4 PF12799.7 EAQ87871.1 - 1e-06 29.0 4.9 0.00024 21.4 0.1 3.8 3 2 1 4 4 4 2 Leucine Rich repeats (2 copies) DUF4349 PF14257.6 EAQ87871.1 - 0.0032 16.9 2.1 0.0054 16.2 2.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4349) PspB PF06667.12 EAQ87871.1 - 0.15 12.1 0.8 0.43 10.7 0.8 1.8 1 0 0 1 1 1 0 Phage shock protein B LRR_6 PF13516.6 EAQ87871.1 - 0.52 10.5 2.8 85 3.6 0.0 4.4 5 0 0 5 5 5 0 Leucine Rich repeat Pkinase PF00069.25 EAQ87872.1 - 2.1e-26 92.9 0.0 2.9e-26 92.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.32 EAQ87872.1 - 7.3e-10 39.3 11.8 4.5e-07 30.5 0.2 5.4 5 0 0 5 5 5 2 WD domain, G-beta repeat Pkinase_Tyr PF07714.17 EAQ87872.1 - 5.6e-08 32.4 0.0 9.2e-08 31.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT PF02985.22 EAQ87872.1 - 5.8e-05 23.0 1.9 5.2 7.6 0.0 5.6 7 0 0 7 7 7 1 HEAT repeat Cnd1 PF12717.7 EAQ87872.1 - 0.00065 19.8 0.1 0.95 9.5 0.0 3.2 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Kinase-like PF14531.6 EAQ87872.1 - 0.0022 17.4 0.0 0.005 16.2 0.0 1.5 1 1 0 1 1 1 1 Kinase-like HEAT_2 PF13646.6 EAQ87872.1 - 0.021 15.2 0.2 5.3 7.5 0.0 3.7 2 1 1 3 3 3 0 HEAT repeats SH3_9 PF14604.6 EAQ87873.1 - 0.00013 21.7 0.2 0.00029 20.6 0.2 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EAQ87873.1 - 0.0021 17.6 0.4 0.0043 16.6 0.4 1.5 1 0 0 1 1 1 1 SH3 domain Mid2 PF04478.12 EAQ87873.1 - 0.017 14.9 0.1 0.031 14.1 0.1 1.3 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor SKG6 PF08693.10 EAQ87873.1 - 0.042 13.3 2.3 0.079 12.4 2.3 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Podoplanin PF05808.11 EAQ87873.1 - 0.049 13.7 0.6 0.097 12.8 0.6 1.5 1 0 0 1 1 1 0 Podoplanin Syndecan PF01034.20 EAQ87873.1 - 0.064 13.2 0.4 0.12 12.4 0.4 1.3 1 0 0 1 1 1 0 Syndecan domain DUF4690 PF15756.5 EAQ87873.1 - 0.085 13.5 2.0 0.14 12.8 0.3 2.2 2 0 0 2 2 2 0 Small Novel Rich in Cartilage PTP_tm PF18861.1 EAQ87873.1 - 0.72 9.8 3.6 1.1 9.2 2.2 1.8 2 0 0 2 2 2 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J Metallophos PF00149.28 EAQ87874.1 - 3e-38 132.4 0.5 4.2e-38 131.9 0.5 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EAQ87874.1 - 0.012 16.1 0.1 0.024 15.1 0.1 1.5 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Exo84_C PF16528.5 EAQ87875.1 - 3.1e-77 259.0 0.0 3.1e-77 259.0 0.0 2.4 3 0 0 3 3 3 1 Exocyst component 84 C-terminal Vps51 PF08700.11 EAQ87875.1 - 7.6e-17 61.2 3.4 7.6e-17 61.2 3.4 2.6 3 0 0 3 3 3 1 Vps51/Vps67 COG2 PF06148.11 EAQ87875.1 - 0.0061 16.6 2.2 0.22 11.6 0.1 2.4 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Prominin PF05478.11 EAQ87875.1 - 0.091 10.7 1.4 0.53 8.2 0.1 2.2 2 0 0 2 2 2 0 Prominin DUF4407 PF14362.6 EAQ87875.1 - 0.24 10.7 4.6 1.4 8.2 4.6 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) HMMR_C PF15908.5 EAQ87875.1 - 0.84 9.9 5.0 0.31 11.3 1.0 2.2 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor C-terminal APG6_N PF17675.1 EAQ87875.1 - 3.2 8.3 15.8 0.56 10.7 5.3 2.5 2 0 0 2 2 2 0 Apg6 coiled-coil region Methyltransf_2 PF00891.18 EAQ87877.1 - 4.6e-25 88.2 0.0 6.9e-25 87.6 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain HTH_24 PF13412.6 EAQ87877.1 - 0.16 11.6 0.0 0.32 10.6 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding MAS20 PF02064.15 EAQ87878.1 - 7.4e-42 142.5 1.2 9.3e-42 142.2 1.2 1.1 1 0 0 1 1 1 1 MAS20 protein import receptor DUF2681 PF10883.8 EAQ87878.1 - 0.026 14.9 1.1 0.049 14.0 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) PASTA PF03793.19 EAQ87878.1 - 0.048 13.5 0.2 0.16 11.8 0.1 1.9 2 0 0 2 2 2 0 PASTA domain LapA_dom PF06305.11 EAQ87878.1 - 0.059 13.2 0.9 0.13 12.1 0.9 1.6 1 1 0 1 1 1 0 Lipopolysaccharide assembly protein A domain TALPID3 PF15324.6 EAQ87878.1 - 2 6.0 4.9 2.5 5.7 4.9 1.0 1 0 0 1 1 1 0 Hedgehog signalling target Radical_SAM PF04055.21 EAQ87879.1 - 4.3e-22 79.3 0.0 1.2e-21 77.8 0.0 1.7 1 1 0 1 1 1 1 Radical SAM superfamily Wyosine_form PF08608.12 EAQ87879.1 - 2e-18 66.5 0.0 4.2e-18 65.5 0.0 1.6 1 0 0 1 1 1 1 Wyosine base formation Flavodoxin_1 PF00258.25 EAQ87879.1 - 2.7e-08 34.1 0.0 9e-07 29.2 0.0 2.6 1 1 0 1 1 1 1 Flavodoxin Flavodoxin_3 PF12641.7 EAQ87879.1 - 0.034 13.8 0.0 0.1 12.3 0.0 1.8 2 0 0 2 2 2 0 Flavodoxin domain DNA_pol_alpha_N PF12254.8 EAQ87879.1 - 0.038 14.1 0.0 15 5.7 0.0 2.8 2 0 0 2 2 2 0 DNA polymerase alpha subunit p180 N terminal EamA PF00892.20 EAQ87880.1 - 9.2e-05 22.6 16.0 0.0018 18.4 16.0 2.0 1 1 0 1 1 1 1 EamA-like transporter family TMEM234 PF10639.9 EAQ87880.1 - 0.27 11.3 6.9 0.04 14.0 3.3 1.5 2 0 0 2 2 2 0 Putative transmembrane family 234 TFIIA_gamma_N PF02268.16 EAQ87881.1 - 2.9e-23 81.6 0.2 4e-23 81.2 0.2 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TFIIA_gamma_C PF02751.14 EAQ87881.1 - 6.9e-23 80.5 1.0 1.1e-22 79.9 1.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit ATP-synt_C PF00137.21 EAQ87882.1 - 4e-26 91.1 36.4 3.9e-15 56.0 11.9 2.9 3 0 0 3 3 3 2 ATP synthase subunit C DUF3671 PF12420.8 EAQ87882.1 - 0.085 12.9 1.6 0.42 10.7 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function SLATT_5 PF18160.1 EAQ87882.1 - 0.2 10.9 0.9 0.45 9.8 0.0 1.9 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 Oxidored_q2 PF00420.24 EAQ87882.1 - 2.5 7.8 7.2 0.54 9.9 1.6 2.6 1 1 1 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L MoCF_biosynth PF00994.24 EAQ87883.1 - 7.2e-52 174.9 1.2 3.6e-27 94.8 0.0 2.4 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.17 EAQ87883.1 - 4.8e-35 120.7 7.9 7.8e-35 120.0 7.9 1.4 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.15 EAQ87883.1 - 3.1e-15 56.1 0.7 8e-15 54.8 0.0 2.2 2 0 0 2 2 2 1 MoeA C-terminal region (domain IV) SelP_N PF04592.14 EAQ87883.1 - 4 6.8 18.1 6.2 6.1 18.1 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Ifi-6-16 PF06140.13 EAQ87884.1 - 4.1e-05 23.4 5.5 5.4e-05 23.0 3.7 2.0 2 0 0 2 2 2 1 Interferon-induced 6-16 family ATP_bind_1 PF03029.17 EAQ87885.1 - 1.4e-72 244.4 0.1 3.1e-72 243.3 0.0 1.6 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_29 PF13555.6 EAQ87885.1 - 0.085 12.6 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain WD40 PF00400.32 EAQ87886.1 - 8.6e-13 48.6 0.1 0.01 16.7 0.0 5.5 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAQ87886.1 - 0.00038 20.7 0.0 6 7.2 0.0 3.8 2 2 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain TT_ORF2 PF02957.15 EAQ87887.1 - 6.1 7.8 6.6 1 10.3 1.7 2.2 2 1 0 2 2 2 0 TT viral ORF2 WD40 PF00400.32 EAQ87888.1 - 7.3e-31 105.8 7.4 1.1e-06 29.2 0.5 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAQ87888.1 - 2.7e-08 34.0 0.1 0.12 12.7 0.0 4.6 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EAQ87888.1 - 6.2e-07 28.4 10.2 0.014 14.1 0.5 5.3 4 2 2 6 6 6 4 Nucleoporin Nup120/160 Hira PF07569.11 EAQ87888.1 - 0.0088 15.8 0.1 6.3 6.5 0.0 3.8 3 1 2 5 5 5 1 TUP1-like enhancer of split BCIP PF13862.6 EAQ87890.1 - 9e-68 228.1 0.7 1.2e-67 227.7 0.7 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein Med20 PF08612.11 EAQ87890.1 - 0.12 11.7 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 TATA-binding related factor (TRF) of subunit 20 of Mediator complex DUF3736 PF12540.8 EAQ87890.1 - 0.13 12.4 0.5 0.23 11.6 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3736) UPF0184 PF03670.13 EAQ87890.1 - 0.24 11.8 0.0 0.24 11.8 0.0 2.9 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0184) COPI_assoc PF08507.10 EAQ87891.1 - 1.2e-33 116.0 3.2 1.2e-33 115.9 3.2 1.0 1 0 0 1 1 1 1 COPI associated protein 5TM-5TMR_LYT PF07694.12 EAQ87891.1 - 0.08 12.5 6.7 0.11 12.0 6.7 1.3 1 1 0 1 1 1 0 5TMR of 5TMR-LYT SAP PF02037.27 EAQ87894.1 - 1.5e-14 53.3 0.1 2.5e-14 52.6 0.1 1.3 1 0 0 1 1 1 1 SAP domain HeH PF12949.7 EAQ87894.1 - 0.11 12.3 0.1 0.22 11.3 0.1 1.5 1 0 0 1 1 1 0 HeH/LEM domain CPSase_sm_chain PF00988.22 EAQ87895.1 - 1.4e-47 160.7 0.0 2.2e-47 160.0 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 EAQ87895.1 - 1.6e-47 161.8 0.0 2.2e-47 161.3 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EAQ87895.1 - 1.1e-05 25.3 0.3 0.0013 18.5 0.3 2.9 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.24 EAQ87895.1 - 0.16 11.8 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 DJ-1/PfpI family ETF PF01012.21 EAQ87896.1 - 1.4e-45 155.4 0.5 1.7e-45 155.1 0.5 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ArfGap PF01412.18 EAQ87897.1 - 1.6e-31 108.8 0.1 2.4e-31 108.3 0.1 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf RRM_1 PF00076.22 EAQ87898.1 - 2.1e-07 30.7 0.0 2e-06 27.5 0.0 2.3 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) IMPDH PF00478.25 EAQ87898.1 - 0.011 14.7 0.1 0.019 14.0 0.1 1.3 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain Flavodoxin_1 PF00258.25 EAQ87899.1 - 1.9e-29 102.7 0.0 8.3e-29 100.6 0.0 1.9 2 0 0 2 2 2 1 Flavodoxin FAD_binding_1 PF00667.20 EAQ87899.1 - 8.9e-25 87.6 0.0 1.4e-24 86.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 EAQ87899.1 - 8e-07 29.7 0.0 1.6e-05 25.5 0.0 2.4 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_3 PF12641.7 EAQ87899.1 - 0.2 11.3 0.0 0.35 10.5 0.0 1.3 1 0 0 1 1 1 0 Flavodoxin domain Asp PF00026.23 EAQ87900.1 - 2e-07 30.7 0.1 1.9e-06 27.5 0.1 2.0 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TraL PF07178.11 EAQ87900.1 - 0.04 14.4 0.1 0.088 13.3 0.1 1.5 1 0 0 1 1 1 0 TraL protein UIM PF02809.20 EAQ87903.1 - 0.003 17.3 20.6 0.046 13.6 3.7 4.1 4 0 0 4 4 4 2 Ubiquitin interaction motif TrbI PF03743.14 EAQ87903.1 - 0.063 13.1 1.5 0.18 11.6 1.5 1.8 1 0 0 1 1 1 0 Bacterial conjugation TrbI-like protein F-box-like PF12937.7 EAQ87903.1 - 0.094 12.6 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 F-box-like F-box PF00646.33 EAQ87903.1 - 0.21 11.5 0.1 0.84 9.6 0.0 1.9 2 0 0 2 2 2 0 F-box domain FYVE_2 PF02318.16 EAQ87904.1 - 5.9 7.1 25.8 1.2 9.4 0.6 3.6 4 0 0 4 4 4 0 FYVE-type zinc finger Clr2 PF10383.9 EAQ87905.1 - 1.9e-32 113.1 0.0 1.7e-31 109.9 0.0 2.3 2 0 0 2 2 2 1 Transcription-silencing protein Clr2 Clr2_transil PF16761.5 EAQ87905.1 - 4.2e-17 62.7 0.2 7.5e-17 61.9 0.2 1.5 1 0 0 1 1 1 1 Transcription-silencing protein, cryptic loci regulator Clr2 Pex14_N PF04695.13 EAQ87905.1 - 1.1 9.9 16.2 2.9 8.5 16.2 1.7 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SUN PF03856.13 EAQ87906.1 - 3.8e-74 249.2 4.4 4.9e-74 248.9 4.4 1.1 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) Thiolase_N PF00108.23 EAQ87908.1 - 7.9e-87 290.9 0.2 1.3e-86 290.1 0.2 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EAQ87908.1 - 5.5e-38 129.4 0.7 1.5e-37 128.0 0.7 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EAQ87908.1 - 9.6e-05 22.1 0.6 0.00022 20.9 0.2 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain UQ_con PF00179.26 EAQ87909.1 - 4.8e-52 175.3 0.1 5.4e-52 175.2 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EAQ87909.1 - 0.00058 19.6 0.0 0.00064 19.4 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 EAQ87909.1 - 0.042 14.1 0.0 0.054 13.8 0.0 1.4 1 1 0 1 1 1 0 RWD domain Kinesin PF00225.23 EAQ87910.1 - 6.1e-113 377.1 0.2 6.1e-113 377.1 0.2 1.7 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EAQ87910.1 - 5.4e-27 94.6 0.1 2.5e-26 92.4 0.1 2.2 1 0 0 1 1 1 1 Microtubule binding LCM PF04072.14 EAQ87912.1 - 3.1e-21 76.2 0.0 1.2e-20 74.3 0.0 1.9 2 1 0 2 2 2 1 Leucine carboxyl methyltransferase TFIID-18kDa PF02269.16 EAQ87913.1 - 7.3e-26 90.0 0.4 2e-24 85.4 0.0 2.6 3 0 0 3 3 3 1 Transcription initiation factor IID, 18kD subunit TAFII28 PF04719.14 EAQ87913.1 - 0.013 15.6 0.0 0.039 14.0 0.0 1.8 1 1 0 1 1 1 0 hTAFII28-like protein conserved region LigT_PEase PF02834.16 EAQ87913.1 - 0.054 13.7 0.2 1.1 9.4 0.0 2.9 3 0 0 3 3 3 0 LigT like Phosphoesterase TPR_10 PF13374.6 EAQ87914.1 - 3.5e-46 153.9 0.9 9.2e-14 50.8 0.0 4.7 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_12 PF13424.6 EAQ87914.1 - 7.4e-31 106.3 8.8 2e-14 53.6 0.1 4.5 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_7 PF13176.6 EAQ87914.1 - 1.3e-09 37.4 0.5 0.0066 16.4 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 EAQ87914.1 - 1.1e-05 25.4 2.2 1.4 9.4 0.0 4.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 EAQ87914.1 - 0.00028 20.7 2.7 4.8 7.5 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 EAQ87914.1 - 0.00084 19.1 0.3 2.4 8.1 0.1 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_4 PF07721.14 EAQ87914.1 - 0.00093 19.6 0.6 4.9 8.1 0.0 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 EAQ87914.1 - 0.0045 17.6 0.0 3.3 8.5 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF1897 PF09005.10 EAQ87914.1 - 0.0051 16.3 0.9 1.2 8.6 0.1 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF1897) TPR_19 PF14559.6 EAQ87914.1 - 0.058 13.9 0.0 13 6.4 0.0 2.8 1 1 1 2 2 2 0 Tetratricopeptide repeat DUF4119 PF13494.6 EAQ87914.1 - 0.11 12.6 0.2 61 3.8 0.0 3.3 2 1 1 3 3 3 0 Domain of unknown function, B. Theta Gene description (DUF4119) TPR_12 PF13424.6 EAQ87915.1 - 1.7e-225 729.9 108.5 2.7e-20 72.4 1.4 9.5 1 1 12 13 13 13 13 Tetratricopeptide repeat TPR_10 PF13374.6 EAQ87915.1 - 2.1e-178 574.2 58.1 8.6e-13 47.7 0.2 14.7 14 0 0 14 14 14 14 Tetratricopeptide repeat TPR_1 PF00515.28 EAQ87915.1 - 4.3e-90 292.2 18.4 5.9e-05 22.7 0.0 15.1 14 0 0 14 14 14 14 Tetratricopeptide repeat TPR_7 PF13176.6 EAQ87915.1 - 2.1e-70 227.7 51.6 0.00023 20.9 0.1 14.7 14 0 0 14 14 14 14 Tetratricopeptide repeat TPR_2 PF07719.17 EAQ87915.1 - 8.5e-68 219.1 23.1 0.0049 16.9 0.3 14.9 14 0 0 14 14 14 14 Tetratricopeptide repeat TPR_8 PF13181.6 EAQ87915.1 - 4.5e-61 198.0 23.5 0.0059 16.7 0.0 14.9 14 0 0 14 14 14 14 Tetratricopeptide repeat TPR_MalT PF17874.1 EAQ87915.1 - 2e-55 188.5 24.9 2.7e-12 46.7 0.3 6.3 1 1 5 6 6 6 6 MalT-like TPR region TPR_16 PF13432.6 EAQ87915.1 - 1.1e-41 141.2 48.8 0.11 13.2 0.1 14.5 14 0 0 14 14 14 14 Tetratricopeptide repeat TPR_14 PF13428.6 EAQ87915.1 - 8.1e-39 129.0 38.4 0.39 11.7 0.0 15.0 14 0 0 14 14 14 14 Tetratricopeptide repeat TPR_4 PF07721.14 EAQ87915.1 - 8.9e-35 115.7 0.0 10 7.1 0.0 15.3 14 0 0 14 14 14 0 Tetratricopeptide repeat TPR_17 PF13431.6 EAQ87915.1 - 7.8e-28 94.8 16.2 1.5 9.3 0.1 16.5 14 2 0 14 14 14 4 Tetratricopeptide repeat TPR_19 PF14559.6 EAQ87915.1 - 3.1e-27 94.9 32.2 0.0067 16.9 0.4 9.1 2 2 6 10 10 10 10 Tetratricopeptide repeat Patatin PF01734.22 EAQ87915.1 - 3.8e-22 79.5 0.2 8.8e-22 78.3 0.2 1.7 1 0 0 1 1 1 1 Patatin-like phospholipase TPR_11 PF13414.6 EAQ87915.1 - 2.6e-16 59.0 55.4 0.22 11.3 0.2 14.5 14 0 0 14 14 14 7 TPR repeat TPR_6 PF13174.6 EAQ87915.1 - 3.6e-13 49.2 61.1 5.1 7.9 0.2 15.4 15 0 0 15 15 14 1 Tetratricopeptide repeat DUF2225 PF09986.9 EAQ87915.1 - 1e-12 48.3 12.6 0.041 13.6 0.3 7.1 1 1 8 9 9 9 5 Uncharacterized protein conserved in bacteria (DUF2225) PPR PF01535.20 EAQ87915.1 - 3.4e-11 42.6 1.5 1.7e+02 2.8 0.0 13.3 15 0 0 15 15 15 0 PPR repeat TPR_21 PF09976.9 EAQ87915.1 - 1.2e-10 41.4 45.8 3 7.5 0.2 13.9 4 3 10 14 14 14 3 Tetratricopeptide repeat-like domain RPN6_N PF18055.1 EAQ87915.1 - 5.1e-07 30.1 20.0 4.7 7.6 0.2 9.0 1 1 8 11 11 11 1 26S proteasome regulatory subunit RPN6 N-terminal domain AAA_16 PF13191.6 EAQ87915.1 - 8.7e-05 23.0 0.9 0.00043 20.7 0.9 2.3 1 1 0 1 1 1 1 AAA ATPase domain Lectin_N PF03954.14 EAQ87915.1 - 0.00056 19.7 9.0 17 5.2 0.0 7.2 4 1 5 9 9 9 0 Hepatic lectin, N-terminal domain NB-ARC PF00931.22 EAQ87915.1 - 0.00086 18.6 0.0 0.0022 17.2 0.0 1.6 1 1 0 1 1 1 1 NB-ARC domain Pedibin PF08182.11 EAQ87915.1 - 0.0012 18.6 9.3 3.1e+02 1.3 0.0 8.6 9 0 0 9 9 9 0 Pedibin/Hym-346 family DUF5344 PF17279.2 EAQ87915.1 - 0.0032 18.0 0.0 20 5.8 0.0 5.5 5 0 0 5 5 5 0 Family of unknown function (DUF5344) ATPase_2 PF01637.18 EAQ87915.1 - 0.011 15.6 0.0 0.023 14.6 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea TPR_10 PF13374.6 EAQ87916.1 - 6e-24 83.2 0.0 2.5e-12 46.3 0.1 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 EAQ87916.1 - 1.2e-14 54.3 0.1 1.7e-08 34.6 0.1 2.0 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 EAQ87916.1 - 4.7e-05 23.1 0.1 0.00059 19.7 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 EAQ87916.1 - 0.00041 20.5 0.1 0.49 10.9 0.1 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 EAQ87916.1 - 0.034 14.3 0.1 0.38 11.0 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF1897 PF09005.10 EAQ87916.1 - 0.049 13.1 0.1 0.09 12.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1897) TPR_5 PF12688.7 EAQ87916.1 - 0.075 13.3 0.0 0.26 11.5 0.0 1.7 1 1 1 2 2 2 0 Tetratrico peptide repeat TPR_1 PF00515.28 EAQ87916.1 - 0.084 12.7 0.1 0.23 11.4 0.0 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Ist1 PF03398.14 EAQ87917.1 - 1.3e-62 210.5 0.5 1.5e-62 210.4 0.5 1.0 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway RepB PF07506.11 EAQ87918.1 - 4.5 7.3 11.7 0.2 11.7 0.1 3.4 3 1 1 4 4 4 0 RepB plasmid partitioning protein Clat_adaptor_s PF01217.20 EAQ87919.1 - 1.2e-56 190.6 1.9 1.3e-56 190.4 1.9 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain MFS_1 PF07690.16 EAQ87920.1 - 4.2e-18 65.4 39.0 2.7e-14 52.9 22.3 2.6 1 1 2 3 3 3 2 Major Facilitator Superfamily Nodulin-like PF06813.13 EAQ87920.1 - 1e-11 44.8 4.3 1e-11 44.8 4.3 2.1 2 0 0 2 2 2 1 Nodulin-like Serinc PF03348.15 EAQ87921.1 - 1.4e-153 511.8 6.1 1.8e-153 511.5 6.1 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) Cys_Met_Meta_PP PF01053.20 EAQ87922.1 - 4.5e-138 459.9 0.0 5.3e-138 459.7 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 EAQ87922.1 - 2.6e-06 26.6 0.1 5.9e-06 25.5 0.1 1.5 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 EAQ87922.1 - 2.9e-05 23.4 0.0 4.5e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Met_gamma_lyase PF06838.11 EAQ87922.1 - 0.00015 20.4 0.1 0.00037 19.2 0.1 1.5 1 1 0 1 1 1 1 Methionine gamma-lyase DegT_DnrJ_EryC1 PF01041.17 EAQ87922.1 - 0.00041 19.8 0.1 0.0016 17.8 0.0 1.9 2 1 1 3 3 3 1 DegT/DnrJ/EryC1/StrS aminotransferase family LytR_C PF13399.6 EAQ87922.1 - 0.12 13.4 0.3 7.2 7.7 0.0 2.9 3 0 0 3 3 3 0 LytR cell envelope-related transcriptional attenuator AAA PF00004.29 EAQ87923.1 - 4.4e-39 133.9 0.0 7.3e-39 133.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EAQ87923.1 - 1e-10 41.3 0.0 2.2e-10 40.2 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_14 PF13173.6 EAQ87923.1 - 7.7e-06 26.0 0.0 1.4e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 EAQ87923.1 - 9.4e-06 25.5 0.0 1.8e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EAQ87923.1 - 1.1e-05 26.0 0.1 0.00042 20.7 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_2 PF07724.14 EAQ87923.1 - 4.7e-05 23.6 0.0 9.8e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 EAQ87923.1 - 5.4e-05 23.2 0.1 0.00085 19.3 0.1 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EAQ87923.1 - 0.00016 22.0 0.1 0.0019 18.5 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EAQ87923.1 - 0.0008 19.6 0.0 0.0018 18.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain TniB PF05621.11 EAQ87923.1 - 0.00098 18.6 0.0 1.5 8.2 0.0 2.5 1 1 0 2 2 2 2 Bacterial TniB protein Mg_chelatase PF01078.21 EAQ87923.1 - 0.0016 17.8 0.1 0.0031 16.9 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 EAQ87923.1 - 0.0024 18.4 0.1 0.0087 16.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 EAQ87923.1 - 0.004 17.5 0.0 0.01 16.2 0.0 1.8 1 0 0 1 1 1 1 RNA helicase IstB_IS21 PF01695.17 EAQ87923.1 - 0.005 16.6 0.0 0.0085 15.8 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein NACHT PF05729.12 EAQ87923.1 - 0.0099 15.8 0.0 0.022 14.7 0.0 1.6 1 1 0 1 1 1 1 NACHT domain AAA_25 PF13481.6 EAQ87923.1 - 0.011 15.3 0.6 0.08 12.5 0.1 2.4 3 0 0 3 3 2 0 AAA domain Zeta_toxin PF06414.12 EAQ87923.1 - 0.012 14.9 0.1 0.11 11.8 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin AAA_24 PF13479.6 EAQ87923.1 - 0.018 14.7 0.0 0.035 13.8 0.0 1.5 1 1 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 EAQ87923.1 - 0.021 14.5 0.0 0.055 13.2 0.0 1.6 2 0 0 2 2 1 0 Sigma-54 interaction domain Rad17 PF03215.15 EAQ87923.1 - 0.022 14.7 0.0 0.061 13.2 0.0 1.7 1 1 0 1 1 1 0 Rad17 P-loop domain AAA_28 PF13521.6 EAQ87923.1 - 0.024 14.9 0.1 0.11 12.7 0.0 2.1 3 0 0 3 3 2 0 AAA domain ATPase_2 PF01637.18 EAQ87923.1 - 0.024 14.6 0.0 0.12 12.2 0.0 1.9 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea Viral_helicase1 PF01443.18 EAQ87923.1 - 0.029 14.1 0.0 0.049 13.4 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase TIP49 PF06068.13 EAQ87923.1 - 0.036 13.3 0.0 0.08 12.1 0.0 1.5 1 1 0 1 1 1 0 TIP49 P-loop domain Oxidored_nitro PF00148.19 EAQ87923.1 - 0.039 12.7 0.0 0.86 8.3 0.0 2.1 2 0 0 2 2 2 0 Nitrogenase component 1 type Oxidoreductase TsaE PF02367.17 EAQ87923.1 - 0.042 13.8 0.0 0.082 12.9 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 EAQ87923.1 - 0.047 12.9 0.0 0.081 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_17 PF13207.6 EAQ87923.1 - 0.06 13.8 0.0 0.17 12.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EAQ87923.1 - 0.061 13.8 0.0 0.13 12.8 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_7 PF12775.7 EAQ87923.1 - 0.076 12.5 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region NB-ARC PF00931.22 EAQ87923.1 - 0.11 11.7 0.0 0.25 10.5 0.0 1.5 2 0 0 2 2 1 0 NB-ARC domain Sigma54_activ_2 PF14532.6 EAQ87923.1 - 0.2 11.8 0.0 0.44 10.6 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Csm1 PF12539.8 EAQ87924.1 - 1.4e-30 105.8 0.0 2.5e-30 104.9 0.0 1.4 1 0 0 1 1 1 1 Chromosome segregation protein Csm1/Pcs1 FPP PF05911.11 EAQ87924.1 - 5.1e-05 21.7 2.0 6.5e-05 21.4 2.0 1.2 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil Rootletin PF15035.6 EAQ87924.1 - 0.0051 16.9 1.2 0.0093 16.0 1.2 1.5 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion Atg14 PF10186.9 EAQ87924.1 - 0.0069 15.5 5.2 0.013 14.6 5.2 1.4 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Spc7 PF08317.11 EAQ87924.1 - 0.0089 14.9 4.5 0.014 14.3 4.5 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein Fmp27_WPPW PF10359.9 EAQ87924.1 - 0.013 14.4 2.1 0.023 13.6 2.1 1.3 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain EzrA PF06160.12 EAQ87924.1 - 0.023 12.9 2.1 0.033 12.4 2.1 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Spc29 PF17082.5 EAQ87924.1 - 0.045 13.6 0.3 0.045 13.6 0.3 1.7 2 0 0 2 2 2 0 Spindle Pole Component 29 AAA_13 PF13166.6 EAQ87924.1 - 0.045 12.4 4.3 0.077 11.6 4.3 1.3 1 0 0 1 1 1 0 AAA domain UPF0242 PF06785.11 EAQ87924.1 - 0.053 13.6 0.8 0.085 13.0 0.8 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Golgin_A5 PF09787.9 EAQ87924.1 - 0.053 13.0 2.0 0.13 11.7 2.0 1.6 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF5094 PF17015.5 EAQ87924.1 - 0.055 13.6 1.2 0.22 11.6 0.0 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF5094) Phlebovirus_NSM PF07246.11 EAQ87924.1 - 0.079 12.3 0.3 0.13 11.6 0.3 1.3 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M ADIP PF11559.8 EAQ87924.1 - 0.17 12.0 5.9 0.36 10.9 5.9 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding V_ATPase_I PF01496.19 EAQ87924.1 - 0.18 9.7 1.0 0.36 8.7 1.0 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMF_TATA_bd PF12325.8 EAQ87924.1 - 0.44 10.8 4.8 1.3 9.2 4.6 1.9 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Macoilin PF09726.9 EAQ87924.1 - 0.44 9.0 15.5 0.59 8.6 15.5 1.1 1 0 0 1 1 1 0 Macoilin family Wtap PF17098.5 EAQ87924.1 - 0.46 10.4 8.4 5.9 6.8 8.5 2.6 1 1 0 1 1 1 0 WTAP/Mum2p family Seryl_tRNA_N PF02403.22 EAQ87924.1 - 0.53 10.5 5.6 0.75 10.1 3.3 2.3 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain KxDL PF10241.9 EAQ87924.1 - 0.54 10.6 3.7 3 8.2 1.0 2.4 1 1 1 2 2 2 0 Uncharacterized conserved protein Sec8_exocyst PF04048.14 EAQ87924.1 - 0.63 9.9 3.1 1.8 8.5 2.8 1.8 1 1 0 1 1 1 0 Sec8 exocyst complex component specific domain DUF641 PF04859.12 EAQ87924.1 - 0.72 10.2 5.6 3 8.2 5.6 2.0 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) Csm1_N PF18504.1 EAQ87924.1 - 0.72 10.2 7.6 1.2 9.6 2.7 3.0 1 1 2 3 3 3 0 Csm1 N-terminal domain DUF2203 PF09969.9 EAQ87924.1 - 4.3 8.1 7.3 1.1 10.0 2.6 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) TPR_MLP1_2 PF07926.12 EAQ87924.1 - 4.5 7.3 14.0 0.61 10.1 8.8 2.2 2 1 0 2 2 1 0 TPR/MLP1/MLP2-like protein CDC37_N PF03234.14 EAQ87924.1 - 4.8 8.1 7.2 0.23 12.3 0.7 2.2 2 1 0 2 2 2 0 Cdc37 N terminal kinase binding Swi5 PF07061.11 EAQ87924.1 - 8.5 6.5 6.6 6.3 7.0 2.5 2.5 1 1 1 2 2 2 0 Swi5 PGAP1 PF07819.13 EAQ87925.1 - 7.5e-93 310.5 0.0 1.1e-92 310.0 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 EAQ87925.1 - 0.00011 22.8 2.0 0.00013 22.7 0.3 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EAQ87925.1 - 0.00078 19.2 0.0 0.0017 18.0 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Palm_thioest PF02089.15 EAQ87925.1 - 0.011 15.6 0.0 0.018 14.9 0.0 1.3 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Hydrolase_4 PF12146.8 EAQ87925.1 - 0.018 14.3 0.0 0.035 13.4 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF676 PF05057.14 EAQ87925.1 - 0.055 13.0 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) UL42 PF17638.2 EAQ87925.1 - 0.056 13.4 0.0 0.25 11.3 0.0 2.2 1 0 0 1 1 1 0 HCMV UL42 Epiglycanin_C PF14654.6 EAQ87925.1 - 0.84 9.7 4.4 0.63 10.1 0.3 2.8 3 0 0 3 3 3 0 Mucin, catalytic, TM and cytoplasmic tail region DNA_mis_repair PF01119.19 EAQ87926.1 - 1.3e-17 63.6 0.0 5e-17 61.7 0.0 2.0 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain MutL_C PF08676.11 EAQ87926.1 - 1.2e-15 57.6 0.1 3.5e-15 56.1 0.1 1.8 1 0 0 1 1 1 1 MutL C terminal dimerisation domain HATPase_c_3 PF13589.6 EAQ87926.1 - 1.1e-05 25.3 0.0 4.5e-05 23.3 0.0 2.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Pyr_redox_2 PF07992.14 EAQ87928.1 - 3.1e-08 33.2 0.0 4.8e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EAQ87928.1 - 0.0046 17.2 0.0 0.011 16.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EAQ87928.1 - 0.063 12.0 0.0 0.099 11.3 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 EAQ87928.1 - 0.07 12.4 0.1 1.2 8.4 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase CbiD PF01888.17 EAQ87928.1 - 0.16 11.3 0.0 0.24 10.7 0.0 1.1 1 0 0 1 1 1 0 CbiD ETF_alpha PF00766.19 EAQ87929.1 - 0.00025 21.0 0.1 0.00025 21.0 0.1 1.0 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain SWIRM-assoc_1 PF16495.5 EAQ87930.1 - 8.9e-33 112.1 4.3 1.9e-32 111.0 4.3 1.6 1 0 0 1 1 1 1 SWIRM-associated region 1 SWIRM PF04433.17 EAQ87930.1 - 3e-32 110.8 0.1 6.6e-32 109.7 0.1 1.6 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.31 EAQ87930.1 - 1.1e-09 38.3 0.0 2.5e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAQ87930.1 - 5.6e-05 23.3 0.2 0.00011 22.4 0.2 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 EAQ87930.1 - 0.0093 16.1 0.1 0.019 15.1 0.1 1.4 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 ZZ PF00569.17 EAQ87930.1 - 0.34 10.8 2.9 0.63 9.9 2.9 1.4 1 0 0 1 1 1 0 Zinc finger, ZZ type Carn_acyltransf PF00755.20 EAQ87931.1 - 1.9e-206 687.3 0.0 2.1e-206 687.1 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase CAP_N PF01213.19 EAQ87932.1 - 5.9e-115 384.1 1.5 5.9e-115 384.1 1.5 1.7 1 1 1 2 2 2 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 EAQ87932.1 - 3e-53 179.6 2.6 4.2e-53 179.2 2.6 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.12 EAQ87932.1 - 0.15 11.8 1.5 0.4 10.4 1.1 1.8 1 1 1 2 2 2 0 Tubulin binding cofactor C PfkB PF00294.24 EAQ87933.1 - 4.6e-14 52.4 0.3 6.2e-09 35.6 0.6 2.1 2 0 0 2 2 2 2 pfkB family carbohydrate kinase MCM PF00493.23 EAQ87934.1 - 3.1e-42 144.2 2.7 3e-31 108.3 0.1 2.2 1 1 1 2 2 2 2 MCM P-loop domain MCM_lid PF17855.1 EAQ87934.1 - 3.7e-25 88.2 1.2 6.6e-25 87.4 1.2 1.4 1 0 0 1 1 1 1 MCM AAA-lid domain Rrn6 PF10214.9 EAQ87934.1 - 2.9 6.3 15.5 4.7 5.6 15.5 1.3 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Pentapeptide_2 PF01469.18 EAQ87935.1 - 0.31 11.0 5.2 10 6.1 0.4 2.8 3 0 0 3 3 3 0 Pentapeptide repeats (8 copies) FoP_duplication PF13865.6 EAQ87935.1 - 2.8 8.6 10.1 0.26 11.9 5.5 1.6 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 Aminotran_3 PF00202.21 EAQ87937.1 - 3.1e-85 286.3 0.0 3.9e-85 286.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 EAQ87937.1 - 0.0089 15.2 0.0 0.018 14.2 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II 14-3-3 PF00244.20 EAQ87937.1 - 0.0099 15.4 0.1 0.016 14.7 0.1 1.2 1 0 0 1 1 1 1 14-3-3 protein Exo70 PF03081.15 EAQ87938.1 - 1.5e-89 300.6 0.0 5.7e-89 298.8 0.0 1.8 2 0 0 2 2 2 1 Exo70 exocyst complex subunit Methyltransf_18 PF12847.7 EAQ87938.1 - 0.053 13.4 0.1 0.19 11.6 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Baculo_PEP_C PF04513.12 EAQ87938.1 - 0.13 12.3 3.0 47 4.0 0.2 3.5 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2203 PF09969.9 EAQ87938.1 - 0.16 12.7 2.0 0.48 11.2 0.1 2.7 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2203) Apolipoprotein PF01442.18 EAQ87938.1 - 0.47 10.3 5.3 0.97 9.3 0.0 2.7 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain Pkinase PF00069.25 EAQ87942.1 - 3.7e-05 23.2 0.0 0.00058 19.3 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ87942.1 - 0.0042 16.4 0.0 0.0061 15.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EAQ87942.1 - 0.0064 15.9 0.0 0.046 13.1 0.0 2.2 3 0 0 3 3 3 1 Lipopolysaccharide kinase (Kdo/WaaP) family AXE1 PF05448.12 EAQ87942.1 - 0.025 13.3 0.0 0.038 12.7 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Pkinase_fungal PF17667.1 EAQ87942.1 - 0.057 12.2 0.0 0.079 11.7 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Astro_capsid_p PF12226.8 EAQ87942.1 - 3 6.9 5.2 4.2 6.4 5.2 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein DNA_pol_phi PF04931.13 EAQ87942.1 - 6 4.8 9.5 8.1 4.4 9.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi Zn_clus PF00172.18 EAQ87943.1 - 1e-05 25.6 10.4 1.8e-05 24.7 10.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MIT PF04212.18 EAQ87943.1 - 0.032 14.3 0.0 0.086 12.9 0.0 1.7 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain B12-binding PF02310.19 EAQ87944.1 - 0.059 13.4 0.2 0.13 12.3 0.2 1.5 2 0 0 2 2 2 0 B12 binding domain DUF5105 PF17118.5 EAQ87944.1 - 0.11 12.2 0.0 0.15 11.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5105) SPOB_a PF14689.6 EAQ87944.1 - 0.27 11.0 0.5 3.4 7.5 0.0 2.6 4 0 0 4 4 4 0 Sensor_kinase_SpoOB-type, alpha-helical domain FAA_hydrolase PF01557.18 EAQ87945.1 - 1.4e-49 168.7 0.0 1.5e-49 168.6 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family BRO1 PF03097.18 EAQ87946.1 - 7.7e-135 449.6 3.6 7.7e-135 449.6 3.6 2.1 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 EAQ87946.1 - 1.9e-69 234.2 15.4 3.7e-69 233.3 15.4 1.5 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV FlaC_arch PF05377.11 EAQ87946.1 - 0.099 13.0 0.1 1.5 9.3 0.0 2.8 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Phage_tail_APC PF16778.5 EAQ87946.1 - 0.11 12.4 2.0 0.5 10.3 0.1 3.0 3 0 0 3 3 3 0 Phage tail assembly chaperone protein COG2 PF06148.11 EAQ87946.1 - 0.17 11.9 3.2 0.2 11.8 0.3 2.6 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1539 PF07560.11 EAQ87946.1 - 0.27 11.3 5.6 0.36 10.9 0.0 3.0 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1539) Gp58 PF07902.11 EAQ87946.1 - 4.7 5.4 11.0 0.19 10.0 0.5 2.4 2 1 1 3 3 3 0 gp58-like protein Fungal_trans PF04082.18 EAQ87947.1 - 1.3e-37 129.3 0.0 1.9e-37 128.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Dna2 PF08696.11 EAQ87947.1 - 0.16 11.7 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 DNA replication factor Dna2 PigN PF04987.14 EAQ87948.1 - 1.8e-166 554.5 28.2 2.3e-166 554.2 28.2 1.1 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.22 EAQ87948.1 - 3.9e-09 36.6 0.1 8.6e-09 35.4 0.1 1.6 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 EAQ87948.1 - 1.8e-08 34.2 0.1 2.6e-08 33.6 0.1 1.2 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.18 EAQ87948.1 - 4.5e-05 22.9 0.0 7.1e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily CDC27 PF09507.10 EAQ87949.1 - 4.3e-74 250.4 35.3 8.6e-73 246.1 35.3 2.5 1 1 0 1 1 1 1 DNA polymerase subunit Cdc27 Glyco_hydro_125 PF06824.11 EAQ87950.1 - 1.1e-176 587.8 0.0 1.3e-176 587.5 0.0 1.0 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) DUF1131 PF06572.12 EAQ87950.1 - 0.06 13.1 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1131) HNH_2 PF13391.6 EAQ87951.1 - 0.00017 21.7 0.0 0.00019 21.5 0.0 1.1 1 0 0 1 1 1 1 HNH endonuclease FSH1 PF03959.13 EAQ87952.1 - 1.4e-30 106.5 0.0 3.3e-30 105.3 0.0 1.6 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 EAQ87952.1 - 0.12 12.2 1.1 1.1 9.0 1.1 2.1 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase p450 PF00067.22 EAQ87953.1 - 1.2e-28 100.1 0.1 1.3e-27 96.6 0.1 2.2 1 1 0 1 1 1 1 Cytochrome P450 Syja_N PF02383.18 EAQ87955.1 - 1.5e-76 257.8 2.1 1.6e-76 257.7 0.0 1.9 2 0 0 2 2 2 1 SacI homology domain HGTP_anticodon2 PF12745.7 EAQ87955.1 - 2.7 7.4 11.1 4.8 6.6 11.1 1.3 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs Zip PF02535.22 EAQ87955.1 - 4.4 6.4 15.8 6.9 5.8 15.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Tti2 PF10521.9 EAQ87956.1 - 3.6e-83 279.4 0.0 5.4e-83 278.8 0.0 1.3 1 0 0 1 1 1 1 Tti2 family PolyA_pol PF01743.20 EAQ87957.1 - 3.1e-24 85.8 0.0 1.1e-22 80.8 0.0 2.6 2 1 0 2 2 2 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 EAQ87957.1 - 2.9e-08 33.3 0.0 8.3e-08 31.9 0.0 1.8 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A Sec7 PF01369.20 EAQ87958.1 - 1.4e-62 210.6 0.0 2.2e-62 210.0 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 EAQ87958.1 - 1.7e-15 57.3 0.0 3.9e-14 52.8 0.0 3.1 4 0 0 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DCB PF16213.5 EAQ87958.1 - 0.00058 19.6 0.2 0.0031 17.2 0.1 2.2 2 0 0 2 2 2 1 Dimerisation and cyclophilin-binding domain of Mon2 Anp1 PF03452.14 EAQ87959.1 - 7.2e-113 376.4 0.1 2.5e-112 374.6 0.0 1.7 2 0 0 2 2 2 1 Anp1 RNase_PH PF01138.21 EAQ87960.1 - 2.6e-24 86.2 0.0 4.2e-24 85.5 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 GDA1_CD39 PF01150.17 EAQ87961.1 - 2.4e-108 362.6 0.0 3.2e-108 362.1 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family MTBP_N PF14918.6 EAQ87961.1 - 0.39 10.2 2.4 1.8 8.0 0.2 2.1 2 0 0 2 2 2 0 MDM2-binding DUF775 PF05603.12 EAQ87962.1 - 2.7e-29 102.1 0.0 3.3e-29 101.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF775) DUF4743 PF15916.5 EAQ87963.1 - 3.8e-12 46.2 0.0 5.6e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4743) NUDIX PF00293.28 EAQ87963.1 - 1.7e-09 37.8 0.1 4.3e-09 36.5 0.1 1.7 1 0 0 1 1 1 1 NUDIX domain RNA_pol_Rpb8 PF03870.15 EAQ87964.1 - 1.1e-28 100.1 0.1 1.2e-28 100.0 0.1 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 PAXNEB PF05625.11 EAQ87965.1 - 2.6e-20 72.9 0.4 3.1e-20 72.7 0.4 1.0 1 0 0 1 1 1 1 PAXNEB protein tRNA_int_endo PF01974.17 EAQ87966.1 - 9.5e-14 51.2 0.0 1.9e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain Phe_tRNA-synt_N PF02912.18 EAQ87966.1 - 0.048 13.6 0.5 0.08 12.9 0.5 1.3 1 0 0 1 1 1 0 Aminoacyl tRNA synthetase class II, N-terminal domain DUF4648 PF15505.6 EAQ87966.1 - 0.13 13.1 1.4 4.5 8.2 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4648) RapA_C PF12137.8 EAQ87966.1 - 0.15 11.0 0.5 0.21 10.5 0.5 1.2 1 0 0 1 1 1 0 RNA polymerase recycling family C-terminal Coat_F PF07875.12 EAQ87966.1 - 0.21 11.8 3.5 9.8 6.5 0.3 2.3 2 0 0 2 2 2 0 Coat F domain zf-C3HC4_3 PF13920.6 EAQ87967.1 - 4.8e-09 35.9 12.4 8e-09 35.2 12.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EAQ87967.1 - 0.057 13.3 12.7 0.096 12.6 12.7 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 RRM_1 PF00076.22 EAQ87968.1 - 1.4e-26 92.1 0.4 1.2e-12 47.4 0.1 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EAQ87968.1 - 6e-05 22.6 0.0 0.0014 18.2 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EAQ87968.1 - 0.0075 16.1 0.0 2.4 8.1 0.0 2.3 2 0 0 2 2 2 2 Occluded RNA-recognition motif PHM7_cyt PF14703.6 EAQ87968.1 - 0.15 12.2 2.8 2.2 8.5 0.1 3.6 2 2 3 5 5 5 0 Cytosolic domain of 10TM putative phosphate transporter RRM_7 PF16367.5 EAQ87968.1 - 0.16 12.1 0.0 15 5.8 0.0 2.5 2 1 0 2 2 2 0 RNA recognition motif ATP-synt_D PF01813.17 EAQ87969.1 - 1.3e-50 172.0 4.5 3.6e-50 170.5 4.5 1.7 1 1 0 1 1 1 1 ATP synthase subunit D DUF2526 PF10735.9 EAQ87969.1 - 0.0089 16.2 0.3 0.025 14.7 0.3 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2526) DUF3847 PF12958.7 EAQ87969.1 - 0.025 14.7 1.1 0.039 14.1 0.0 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3847) Suf PF05843.14 EAQ87970.1 - 6.5e-13 49.3 7.8 0.054 13.5 0.0 6.3 3 1 1 4 4 4 4 Suppressor of forked protein (Suf) TPR_14 PF13428.6 EAQ87970.1 - 1.7e-12 47.0 12.9 2.9 8.9 0.0 10.3 9 1 1 10 10 10 3 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 EAQ87970.1 - 7.6e-09 35.6 7.5 0.23 11.4 0.1 6.2 6 0 0 6 6 6 4 Mad3/BUB1 homology region 1 TPR_8 PF13181.6 EAQ87970.1 - 3.7e-08 33.0 2.8 0.16 12.2 0.0 6.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_15 PF13429.6 EAQ87970.1 - 5.2e-07 29.1 1.5 0.00015 21.1 0.4 3.7 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 EAQ87970.1 - 3e-06 27.4 2.7 2 8.7 0.0 6.1 7 0 0 7 7 7 1 Tetratricopeptide repeat RPN7 PF10602.9 EAQ87970.1 - 2.6e-05 24.0 1.4 0.00022 21.0 0.2 3.1 4 1 0 4 4 3 1 26S proteasome subunit RPN7 TPR_2 PF07719.17 EAQ87970.1 - 0.00041 20.2 15.4 0.15 12.2 0.0 6.7 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_19 PF14559.6 EAQ87970.1 - 0.00044 20.7 2.4 23 5.6 0.0 5.6 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_4 PF07721.14 EAQ87970.1 - 0.00098 19.5 0.2 0.053 14.2 0.0 3.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 EAQ87970.1 - 0.0065 16.8 1.0 22 5.7 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 EAQ87970.1 - 0.022 14.7 1.1 0.65 10.2 0.0 4.1 6 0 0 6 6 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 EAQ87970.1 - 0.14 12.0 0.0 3.7 7.5 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 EAQ87970.1 - 0.31 11.8 6.2 66 4.5 0.0 6.4 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_10 PF13374.6 EAQ87970.1 - 2.8 7.9 11.9 50 3.9 0.0 6.1 7 0 0 7 7 7 0 Tetratricopeptide repeat Tannase PF07519.11 EAQ87971.1 - 0.047 12.6 0.0 0.047 12.6 0.0 1.0 1 0 0 1 1 1 0 Tannase and feruloyl esterase adh_short PF00106.25 EAQ87972.1 - 8.2e-28 97.2 0.0 1.2e-27 96.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EAQ87972.1 - 1.4e-18 67.3 0.0 1.9e-18 66.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 EAQ87972.1 - 0.18 11.2 0.0 0.24 10.7 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Trp_oprn_chp PF09534.10 EAQ87973.1 - 0.089 12.6 6.2 0.18 11.6 6.2 1.5 1 1 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) PrgI PF12666.7 EAQ87973.1 - 0.22 12.2 0.5 0.63 10.8 0.0 1.9 2 0 0 2 2 2 0 PrgI family protein MFS_1 PF07690.16 EAQ87974.1 - 4.3e-13 48.9 14.6 5.6e-13 48.5 14.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EAQ87974.1 - 0.00028 19.9 3.3 0.0003 19.8 3.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter NAR2 PF16974.5 EAQ87974.1 - 0.52 9.7 1.6 0.91 8.9 1.6 1.4 1 1 0 1 1 1 0 High-affinity nitrate transporter accessory NiFe_hyd_SSU_C PF14720.6 EAQ87975.1 - 0.14 12.6 0.0 0.22 11.9 0.0 1.2 1 0 0 1 1 1 0 NiFe/NiFeSe hydrogenase small subunit C-terminal Fungal_trans PF04082.18 EAQ87976.1 - 8.5e-24 84.0 0.2 1.8e-23 83.0 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain ThiF PF00899.21 EAQ87977.1 - 1.1e-17 64.2 0.0 3.1e-16 59.5 0.0 2.8 1 1 0 1 1 1 1 ThiF family Egh16-like PF11327.8 EAQ87978.1 - 5.8e-55 186.6 8.8 5.8e-55 186.6 8.8 1.5 2 0 0 2 2 2 1 Egh16-like virulence factor NmrA PF05368.13 EAQ87978.1 - 0.12 11.9 0.3 0.19 11.3 0.3 1.3 1 0 0 1 1 1 0 NmrA-like family PEMT PF04191.13 EAQ87979.1 - 2.4e-57 191.9 16.6 6.5e-37 126.2 1.7 3.3 3 0 0 3 3 3 2 Phospholipid methyltransferase HECW_N PF16562.5 EAQ87979.1 - 0.021 14.6 0.0 0.1 12.4 0.0 2.1 2 0 0 2 2 2 0 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 SKICH PF17751.1 EAQ87979.1 - 0.021 15.3 0.1 0.51 10.9 0.1 2.4 1 1 0 1 1 1 0 SKICH domain LapA_dom PF06305.11 EAQ87980.1 - 6.5 6.6 5.4 0.51 10.2 0.2 1.8 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain eIF3g PF12353.8 EAQ87981.1 - 7.2e-44 149.2 1.2 1.3e-43 148.3 1.2 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.22 EAQ87981.1 - 2.1e-16 59.5 0.0 4.1e-16 58.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH_7 PF18586.1 EAQ87981.1 - 0.027 14.8 0.2 0.054 13.8 0.2 1.4 1 0 0 1 1 1 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 1 PH PF00169.29 EAQ87982.1 - 0.22 12.1 0.0 0.42 11.1 0.0 1.5 1 0 0 1 1 1 0 PH domain JAKMIP_CC3 PF16034.5 EAQ87983.1 - 0.0001 22.3 0.4 0.17 11.8 0.0 2.3 2 0 0 2 2 2 2 JAKMIP CC3 domain DUF2046 PF09755.9 EAQ87983.1 - 0.0017 17.7 4.4 0.0018 17.6 1.2 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein H4 (DUF2046) KIAA1430 PF13879.6 EAQ87983.1 - 0.02 15.6 4.0 0.031 15.0 0.9 2.3 2 0 0 2 2 2 0 KIAA1430 homologue Pox_A_type_inc PF04508.12 EAQ87983.1 - 0.036 13.9 2.2 0.11 12.4 2.2 1.9 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat SlyX PF04102.12 EAQ87983.1 - 0.11 13.1 10.1 1.3 9.6 3.8 2.7 2 0 0 2 2 2 0 SlyX TMCO5 PF14992.6 EAQ87983.1 - 0.15 11.6 5.9 0.76 9.3 0.9 2.1 2 0 0 2 2 2 0 TMCO5 family Med9 PF07544.13 EAQ87983.1 - 0.37 10.9 4.9 1.5 9.0 0.0 2.5 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 SKA2 PF16740.5 EAQ87983.1 - 0.56 10.0 6.6 0.11 12.2 1.0 2.2 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 ZapB PF06005.12 EAQ87983.1 - 1.2 9.6 11.6 4.8 7.7 2.9 2.5 2 0 0 2 2 2 0 Cell division protein ZapB Csm1_N PF18504.1 EAQ87983.1 - 1.4 9.4 9.7 6.4 7.2 0.4 2.4 2 0 0 2 2 2 0 Csm1 N-terminal domain FlxA PF14282.6 EAQ87983.1 - 1.5 8.9 17.3 0.64 10.0 6.7 2.5 2 1 0 2 2 2 0 FlxA-like protein Uso1_p115_C PF04871.13 EAQ87983.1 - 2.3 8.6 15.2 1.7 9.0 6.2 2.2 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region LPP PF04728.13 EAQ87983.1 - 2.9 8.4 9.4 0.51 10.8 1.9 2.5 2 1 0 2 2 2 0 Lipoprotein leucine-zipper Fib_alpha PF08702.10 EAQ87983.1 - 4 7.6 7.6 17 5.6 1.0 2.3 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF4140 PF13600.6 EAQ87983.1 - 4.2 7.9 7.2 13 6.3 0.8 2.8 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) HOOK PF05622.12 EAQ87983.1 - 5 5.2 11.2 0.28 9.3 2.3 2.0 2 0 0 2 2 2 0 HOOK protein DAO PF01266.24 EAQ87984.1 - 1.4e-60 205.8 3.7 1.5e-60 205.6 3.7 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EAQ87984.1 - 0.00035 20.7 1.0 0.00087 19.5 1.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EAQ87984.1 - 0.033 13.4 0.1 0.24 10.6 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EAQ87984.1 - 0.14 12.7 0.0 1.3 9.6 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF2415 PF10313.9 EAQ87985.1 - 7.6e-15 54.6 0.0 1.7e-14 53.4 0.0 1.7 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) ANAPC4_WD40 PF12894.7 EAQ87985.1 - 0.00088 19.5 0.0 3.4 8.0 0.0 3.8 2 1 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EAQ87985.1 - 0.0089 16.9 0.2 4.2 8.4 0.0 3.6 3 0 0 3 3 3 1 WD domain, G-beta repeat Tmemb_cc2 PF10267.9 EAQ87985.1 - 0.25 10.5 3.4 0.39 9.8 3.4 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein HSP70 PF00012.20 EAQ87986.1 - 1.4e-261 868.9 17.1 1.7e-261 868.7 17.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EAQ87986.1 - 2.8e-12 46.1 1.0 2.8e-12 46.1 1.0 1.8 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 EAQ87986.1 - 0.0008 19.2 0.1 0.0021 17.8 0.1 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Big_3_4 PF13754.6 EAQ87986.1 - 0.044 13.5 0.0 2 8.2 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function SMBP PF16785.5 EAQ87986.1 - 0.64 10.3 12.2 0.23 11.7 7.2 2.7 3 0 0 3 3 3 0 Small metal-binding protein TipAS PF07739.13 EAQ87986.1 - 5.5 7.6 7.5 20 5.7 2.4 2.5 1 1 0 2 2 2 0 TipAS antibiotic-recognition domain SRP68 PF16969.5 EAQ87987.1 - 8.3e-212 705.1 0.1 9.6e-212 704.9 0.1 1.0 1 0 0 1 1 1 1 RNA-binding signal recognition particle 68 PPR_2 PF13041.6 EAQ87988.1 - 8.9e-16 57.8 1.4 7.4e-06 26.1 0.0 5.7 4 1 1 5 5 5 3 PPR repeat family PPR PF01535.20 EAQ87988.1 - 4.5e-13 48.5 0.4 0.0017 18.4 0.0 7.7 8 0 0 8 8 8 2 PPR repeat PPR_3 PF13812.6 EAQ87988.1 - 4.1e-08 33.2 0.0 0.0016 18.5 0.0 4.5 4 1 1 5 5 5 1 Pentatricopeptide repeat domain PPR_1 PF12854.7 EAQ87988.1 - 5.7e-06 25.9 0.0 0.29 10.9 0.0 3.7 3 0 0 3 3 3 2 PPR repeat TPR_14 PF13428.6 EAQ87988.1 - 3.1e-05 24.4 4.6 1.7 9.7 0.0 6.4 4 1 1 5 5 5 1 Tetratricopeptide repeat ATP13 PF12921.7 EAQ87988.1 - 0.0013 18.5 0.1 0.009 15.9 0.0 2.5 3 0 0 3 3 3 1 Mitochondrial ATPase expression TPR_19 PF14559.6 EAQ87988.1 - 0.0014 19.0 3.4 2.2 8.8 0.0 4.4 3 1 0 4 4 4 1 Tetratricopeptide repeat PPR_long PF17177.4 EAQ87988.1 - 0.0019 17.6 0.4 0.77 9.1 0.0 2.9 2 1 1 3 3 3 2 Pentacotripeptide-repeat region of PRORP TPR_16 PF13432.6 EAQ87988.1 - 0.0041 17.7 3.2 0.0071 17.0 0.0 3.2 3 0 0 3 3 2 1 Tetratricopeptide repeat Wzy_C_2 PF11846.8 EAQ87988.1 - 0.051 13.5 1.7 7.6 6.4 0.0 4.1 4 0 0 4 4 4 0 Virulence factor membrane-bound polymerase, C-terminal MRP-S27 PF10037.9 EAQ87988.1 - 0.063 12.1 0.1 0.42 9.4 0.1 2.1 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S27 TPR_2 PF07719.17 EAQ87988.1 - 0.084 13.0 2.8 14 6.1 0.0 4.4 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 EAQ87988.1 - 0.61 10.2 2.3 5.6 7.2 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 EAQ87988.1 - 1.3 9.9 3.7 1.7 9.5 0.1 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat PWI PF01480.17 EAQ87989.1 - 9e-08 32.3 0.0 1.8e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 PWI domain RRM_1 PF00076.22 EAQ87989.1 - 1.9e-07 30.8 2.0 1.1e-06 28.3 0.2 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.24 EAQ87989.1 - 6.5e-07 29.1 3.7 1.1e-06 28.3 3.7 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EAQ87989.1 - 4.5e-06 26.5 3.5 8.3e-06 25.7 3.5 1.5 1 0 0 1 1 1 1 Zinc finger domain Nup35_RRM_2 PF14605.6 EAQ87989.1 - 0.00058 19.8 0.0 0.029 14.4 0.0 2.5 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 EAQ87989.1 - 0.014 15.2 0.0 0.052 13.4 0.0 1.8 2 0 0 2 2 2 0 Occluded RNA-recognition motif RRM_5 PF13893.6 EAQ87989.1 - 0.036 13.7 0.0 0.069 12.8 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 EAQ87989.1 - 0.036 14.3 6.2 0.42 10.8 0.1 2.7 2 1 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter zf-CCCH_2 PF14608.6 EAQ87989.1 - 0.073 13.6 2.7 0.13 12.8 2.7 1.4 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger RRM_3 PF08777.11 EAQ87989.1 - 0.093 12.8 8.3 0.52 10.4 0.1 2.8 3 0 0 3 3 2 0 RNA binding motif AAA_23 PF13476.6 EAQ87989.1 - 0.12 12.8 5.4 0.14 12.6 3.3 2.0 2 0 0 2 2 2 0 AAA domain MTHFR PF02219.17 EAQ87990.1 - 2.1e-112 375.1 0.0 4e-112 374.2 0.0 1.4 2 0 0 2 2 2 1 Methylenetetrahydrofolate reductase DUF676 PF05057.14 EAQ87991.1 - 7.6e-44 149.8 0.0 1.3e-28 100.0 0.0 3.2 2 1 1 3 3 3 3 Putative serine esterase (DUF676) Cwf_Cwc_15 PF04889.12 EAQ87991.1 - 1.4 8.6 6.8 3.3 7.4 6.8 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Zn_clus PF00172.18 EAQ87992.1 - 0.12 12.5 7.9 0.3 11.2 7.9 1.7 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-BED PF02892.15 EAQ87992.1 - 0.36 10.9 2.1 0.62 10.1 0.2 2.2 2 0 0 2 2 2 0 BED zinc finger zf-C2H2_6 PF13912.6 EAQ87992.1 - 2.9 8.0 4.6 2.5 8.2 0.7 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger Sec5 PF15469.6 EAQ87993.1 - 9.2e-35 120.2 0.0 2.2e-34 118.9 0.0 1.7 1 0 0 1 1 1 1 Exocyst complex component Sec5 Vps51 PF08700.11 EAQ87993.1 - 0.0017 18.4 0.4 0.013 15.5 0.1 2.6 2 0 0 2 2 2 1 Vps51/Vps67 RasGAP_C PF03836.15 EAQ87993.1 - 1.9 8.7 3.9 16 5.6 0.1 3.2 3 0 0 3 3 3 0 RasGAP C-terminus Iso_dh PF00180.20 EAQ87994.1 - 3.4e-98 329.0 0.0 3.9e-98 328.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Phage_30_3 PF08010.11 EAQ87994.1 - 0.0079 16.0 0.0 0.02 14.7 0.0 1.6 1 0 0 1 1 1 1 Bacteriophage protein GP30.3 BSP PF04450.12 EAQ87997.1 - 2.2e-76 256.3 0.0 2.6e-76 256.0 0.0 1.0 1 0 0 1 1 1 1 Peptidase of plants and bacteria CLASP_N PF12348.8 EAQ87998.1 - 4.3e-138 458.3 1.9 3.5e-92 308.1 0.1 2.4 2 0 0 2 2 2 2 CLASP N terminal HEAT PF02985.22 EAQ87998.1 - 0.00015 21.8 0.0 1.7 9.1 0.0 4.6 3 0 0 3 3 3 2 HEAT repeat Cnd1 PF12717.7 EAQ87998.1 - 0.046 13.8 0.1 4.3 7.3 0.0 3.4 2 2 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 EAQ87998.1 - 0.082 13.5 0.0 43 4.8 0.0 3.6 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region RhoGAP PF00620.27 EAQ88000.1 - 3.3e-46 156.9 0.0 3.3e-46 156.9 0.0 2.7 2 2 1 3 3 3 1 RhoGAP domain LIM PF00412.22 EAQ88000.1 - 6e-14 52.0 19.4 3.9e-09 36.6 2.2 2.4 2 0 0 2 2 2 2 LIM domain zf-C3HC4_3 PF13920.6 EAQ88000.1 - 0.013 15.3 2.1 0.013 15.3 2.1 3.2 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) KASH_CCD PF14662.6 EAQ88000.1 - 0.98 9.2 21.9 3.2 7.6 21.9 1.9 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH rRNA_processing PF08524.11 EAQ88001.1 - 0.0018 18.3 8.5 0.0018 18.3 8.5 2.2 1 1 1 2 2 2 1 rRNA processing TFIIA PF03153.13 EAQ88001.1 - 0.033 14.2 20.6 0.04 13.9 20.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4210 PF13915.6 EAQ88002.1 - 8.2e-33 112.8 0.1 2.3e-32 111.4 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.6 EAQ88002.1 - 2.5e-22 78.8 0.7 7e-22 77.3 0.7 1.8 1 0 0 1 1 1 1 Chromosome segregation during meiosis DUF5398 PF17376.2 EAQ88002.1 - 0.096 13.3 0.0 0.18 12.5 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5398) GTP_EFTU PF00009.27 EAQ88003.1 - 2.2e-64 216.6 0.1 3.1e-64 216.1 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 EAQ88003.1 - 1.8e-13 50.7 2.0 4e-13 49.6 0.1 2.7 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.6 EAQ88003.1 - 4.2e-12 46.0 0.0 1.2e-11 44.5 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.18 EAQ88003.1 - 2e-09 37.2 0.0 7.2e-09 35.5 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G, domain IV MMR_HSR1 PF01926.23 EAQ88003.1 - 0.00042 20.4 0.1 0.00095 19.2 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FAST_1 PF06743.15 EAQ88003.1 - 0.098 12.6 0.0 1.2 9.2 0.1 2.3 2 0 0 2 2 2 0 FAST kinase-like protein, subdomain 1 Solute_trans_a PF03619.16 EAQ88004.1 - 3e-72 243.3 0.9 3.7e-72 243.0 0.9 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Na_Ca_ex PF01699.24 EAQ88006.1 - 4.2e-41 140.4 43.3 4.4e-21 75.4 12.6 2.4 3 0 0 3 3 3 2 Sodium/calcium exchanger protein IML1 PF12257.8 EAQ88007.1 - 9.7e-117 389.1 0.0 1.4e-116 388.7 0.0 1.2 1 0 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 DEP PF00610.21 EAQ88007.1 - 6.8e-31 106.1 0.2 1.7e-30 104.9 0.2 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Cation_efflux PF01545.21 EAQ88008.1 - 1.3e-32 113.1 0.0 1.9e-32 112.6 0.0 1.2 1 0 0 1 1 1 1 Cation efflux family FNIP_N PF14636.6 EAQ88009.1 - 8.9e-29 101.5 19.4 1.9e-28 100.4 0.1 5.1 3 2 2 5 5 5 2 Folliculin-interacting protein N-terminus FNIP_C PF14638.6 EAQ88009.1 - 0.022 14.4 0.0 0.05 13.2 0.0 1.5 1 0 0 1 1 1 0 Folliculin-interacting protein C-terminus Lactonase PF10282.9 EAQ88010.1 - 5e-88 295.7 0.0 5.6e-88 295.5 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Spond_N PF06468.13 EAQ88010.1 - 0.19 11.8 0.1 0.35 11.0 0.1 1.4 1 0 0 1 1 1 0 Spondin_N Zn_clus PF00172.18 EAQ88012.1 - 4.8e-09 36.2 7.9 4.8e-09 36.2 7.9 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DEAD PF00270.29 EAQ88015.1 - 5.1e-50 169.7 0.2 3.6e-49 166.9 0.0 2.2 2 1 1 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EAQ88015.1 - 8.8e-26 90.4 0.2 2e-24 86.0 0.1 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 EAQ88015.1 - 1.3e-21 76.6 0.9 1.3e-21 76.6 0.9 2.3 3 0 0 3 3 3 1 DBP10CT (NUC160) domain ERCC3_RAD25_C PF16203.5 EAQ88015.1 - 0.0095 15.2 0.0 0.017 14.4 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase DnaJ PF00226.31 EAQ88016.1 - 7.3e-14 51.6 0.4 2.4e-13 50.0 0.1 2.1 2 0 0 2 2 2 1 DnaJ domain Afi1 PF07792.12 EAQ88016.1 - 0.62 10.5 6.6 1.4 9.4 6.6 1.6 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking HEAT PF02985.22 EAQ88017.1 - 0.05 13.9 0.1 1.3 9.4 0.0 3.5 4 0 0 4 4 4 0 HEAT repeat CNDH2_C PF16858.5 EAQ88017.1 - 0.26 11.1 0.9 5.3 6.8 1.3 2.1 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Arm PF00514.23 EAQ88017.1 - 0.32 11.1 3.0 32 4.7 0.4 3.5 3 1 0 3 3 3 0 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 EAQ88017.1 - 0.39 11.3 2.2 38 4.9 0.0 4.8 5 1 0 5 5 5 0 HEAT-like repeat SDA1 PF05285.12 EAQ88017.1 - 1.1 8.7 6.7 1.7 8.0 6.7 1.2 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 EAQ88017.1 - 1.3 7.1 9.1 2.2 6.4 9.1 1.2 1 0 0 1 1 1 0 Nop14-like family DUF202 PF02656.15 EAQ88019.1 - 8.8e-12 45.3 0.1 1.1e-11 44.9 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF202) COX4_pro_2 PF07835.12 EAQ88019.1 - 0.029 14.5 0.0 0.044 13.9 0.0 1.2 1 0 0 1 1 1 0 Bacterial aa3 type cytochrome c oxidase subunit IV RPA_C PF08784.11 EAQ88020.1 - 1.7e-14 54.3 0.8 4.2e-14 53.1 0.0 1.9 2 0 0 2 2 2 1 Replication protein A C terminal tRNA_anti-codon PF01336.25 EAQ88020.1 - 1.1e-06 28.5 0.2 1.7e-06 27.9 0.2 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain MarR_2 PF12802.7 EAQ88020.1 - 0.0013 18.6 0.0 0.0029 17.5 0.0 1.5 1 0 0 1 1 1 1 MarR family RMI2 PF16100.5 EAQ88020.1 - 0.0062 16.3 0.0 0.01 15.7 0.0 1.2 1 0 0 1 1 1 1 RecQ-mediated genome instability protein 2 Serglycin PF04360.12 EAQ88021.1 - 0.2 11.6 3.1 0.34 10.9 3.1 1.3 1 0 0 1 1 1 0 Serglycin NUDIX PF00293.28 EAQ88022.1 - 7.3e-13 48.7 0.0 1.9e-11 44.1 0.0 2.2 1 1 0 1 1 1 1 NUDIX domain MatE PF01554.18 EAQ88023.1 - 4e-47 159.9 20.2 1.8e-25 89.5 9.0 2.5 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.6 EAQ88023.1 - 3e-05 24.1 20.5 0.0033 17.5 8.7 3.2 3 0 0 3 3 3 2 Polysaccharide biosynthesis C-terminal domain ATP-synt_I PF03899.15 EAQ88023.1 - 0.0035 17.7 0.5 0.0035 17.7 0.5 4.0 4 2 0 4 4 4 1 ATP synthase I chain Npa1 PF11707.8 EAQ88024.1 - 2.1e-86 290.4 0.0 5.7e-86 288.9 0.0 1.8 1 0 0 1 1 1 1 Ribosome 60S biogenesis N-terminal NopRA1 PF16201.5 EAQ88024.1 - 9.5e-59 198.4 0.3 2.7e-58 196.9 0.1 1.9 2 0 0 2 2 2 1 Nucleolar pre-ribosomal-associated protein 1 Mlh1_C PF16413.5 EAQ88026.1 - 6.3e-76 255.3 0.0 1.3e-75 254.3 0.0 1.4 2 0 0 2 2 2 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 EAQ88026.1 - 2.8e-35 120.6 0.1 5e-35 119.7 0.1 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain Thioredoxin_8 PF13905.6 EAQ88026.1 - 0.14 12.5 0.1 0.28 11.5 0.1 1.5 1 0 0 1 1 1 0 Thioredoxin-like HATPase_c_3 PF13589.6 EAQ88027.1 - 4.1e-06 26.6 0.1 5.8e-06 26.2 0.1 1.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 EAQ88027.1 - 0.0019 18.7 0.1 0.0025 18.3 0.1 1.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase F-box-like PF12937.7 EAQ88029.1 - 0.0032 17.3 0.2 0.0088 15.9 0.2 1.7 1 0 0 1 1 1 1 F-box-like CAP_N PF01213.19 EAQ88030.1 - 3 7.2 8.3 4.9 6.5 8.3 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal FAM75 PF14650.6 EAQ88030.1 - 3.9 6.9 15.4 7.3 6.0 15.4 1.3 1 0 0 1 1 1 0 FAM75 family Mito_carr PF00153.27 EAQ88031.1 - 0.11 12.4 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial carrier protein Lon_C PF05362.13 EAQ88033.1 - 4.8e-66 222.2 0.5 8.2e-66 221.5 0.5 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 EAQ88033.1 - 3.2e-27 95.8 0.0 6.4e-27 94.8 0.0 1.5 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 EAQ88033.1 - 5.7e-23 81.8 0.0 1.3e-22 80.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EAQ88033.1 - 7.5e-09 35.7 0.0 3.8e-08 33.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) ChlI PF13541.6 EAQ88033.1 - 1.2e-07 31.6 0.2 3.8e-07 30.0 0.0 2.0 2 0 0 2 2 2 1 Subunit ChlI of Mg-chelatase AAA_16 PF13191.6 EAQ88033.1 - 3.3e-05 24.3 0.0 9.2e-05 22.9 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain IstB_IS21 PF01695.17 EAQ88033.1 - 0.00027 20.7 0.0 0.00069 19.4 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_3 PF07726.11 EAQ88033.1 - 0.0003 20.6 0.0 0.00081 19.3 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EAQ88033.1 - 0.00095 18.9 0.0 0.0035 17.1 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EAQ88033.1 - 0.0012 19.1 0.0 0.031 14.6 0.0 2.8 2 1 1 3 3 2 1 AAA domain AAA_2 PF07724.14 EAQ88033.1 - 0.0013 18.9 0.0 0.0038 17.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 EAQ88033.1 - 0.019 15.2 0.0 0.041 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 EAQ88033.1 - 0.019 14.2 0.1 0.043 13.0 0.1 1.5 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_25 PF13481.6 EAQ88033.1 - 0.019 14.5 0.1 0.11 12.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 EAQ88033.1 - 0.077 13.5 0.0 0.3 11.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EAQ88033.1 - 0.091 12.7 0.0 0.24 11.3 0.0 1.7 1 0 0 1 1 1 0 NACHT domain AAA_18 PF13238.6 EAQ88033.1 - 0.1 13.2 0.0 0.25 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 EAQ88033.1 - 0.11 11.9 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_14 PF13173.6 EAQ88033.1 - 0.15 12.1 0.0 0.32 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 EAQ88033.1 - 0.15 11.4 0.1 0.31 10.4 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 EAQ88033.1 - 0.19 12.1 0.0 0.56 10.6 0.0 1.8 1 0 0 1 1 1 0 RNA helicase MOR2-PAG1_N PF14222.6 EAQ88034.1 - 1.8e-224 746.8 0.0 2.8e-224 746.2 0.0 1.3 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.6 EAQ88034.1 - 1.2e-95 320.2 0.1 5.3e-95 318.1 0.0 2.3 2 0 0 2 2 2 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.6 EAQ88034.1 - 7.4e-32 110.0 2.5 8.5e-13 46.9 0.0 3.7 1 1 2 3 3 3 3 Cell morphogenesis central region HEAT PF02985.22 EAQ88034.1 - 3.2 8.2 4.4 62 4.3 0.0 4.6 5 0 0 5 5 5 0 HEAT repeat FAD_binding_1 PF00667.20 EAQ88035.1 - 1.7e-63 214.1 0.0 2.5e-63 213.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 EAQ88035.1 - 2.1e-34 118.8 0.2 4.6e-34 117.7 0.2 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 EAQ88035.1 - 1.3e-12 48.3 0.0 8.1e-12 45.8 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 EAQ88035.1 - 0.018 15.3 0.1 0.06 13.6 0.0 1.9 2 0 0 2 2 2 0 Flavodoxin domain RRM_1 PF00076.22 EAQ88036.1 - 2.7e-25 88.0 0.0 7.5e-12 44.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RIO1 PF01163.22 EAQ88037.1 - 1.3e-40 139.0 0.1 6e-28 97.7 0.0 2.3 2 0 0 2 2 2 2 RIO1 family Rio2_N PF09202.11 EAQ88037.1 - 3.8e-32 110.3 0.1 1e-31 108.9 0.1 1.8 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.23 EAQ88037.1 - 4.3e-07 30.1 0.3 0.0025 17.8 0.1 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 EAQ88037.1 - 6.4e-06 25.7 0.0 0.017 14.4 0.0 2.5 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family RXT2_N PF08595.11 EAQ88037.1 - 1.1 9.3 9.8 0.89 9.6 2.9 2.2 2 0 0 2 2 2 0 RXT2-like, N-terminal CPSF100_C PF13299.6 EAQ88037.1 - 3 8.0 5.9 8.6 6.5 0.3 2.2 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal DUF1840 PF08895.11 EAQ88037.1 - 6 7.2 7.6 4.8 7.6 2.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) FAM176 PF14851.6 EAQ88037.1 - 6.1 6.5 10.0 3.2 7.4 3.1 2.2 2 0 0 2 2 2 0 FAM176 family RPN1_RPN2_N PF17781.1 EAQ88038.1 - 3.2e-115 384.8 0.9 5.9e-115 383.9 0.9 1.4 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 EAQ88038.1 - 1.5e-29 101.7 0.0 2.8e-29 100.9 0.0 1.4 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 EAQ88038.1 - 5.1e-22 77.1 21.4 5.4e-08 32.9 0.2 8.9 8 0 0 8 8 8 3 Proteasome/cyclosome repeat HEAT_2 PF13646.6 EAQ88038.1 - 5.8e-08 33.0 0.3 0.00078 19.8 0.0 3.8 3 1 1 4 4 4 2 HEAT repeats HEAT_EZ PF13513.6 EAQ88038.1 - 0.044 14.3 0.8 2.1 9.0 0.2 3.1 1 1 1 2 2 2 0 HEAT-like repeat HEAT PF02985.22 EAQ88038.1 - 0.11 12.8 0.0 34 5.1 0.0 3.8 3 0 0 3 3 3 0 HEAT repeat Sec1 PF00995.23 EAQ88039.1 - 3.3e-100 337.0 0.0 4.6e-84 283.7 0.0 2.1 1 1 1 2 2 2 2 Sec1 family Iso_dh PF00180.20 EAQ88040.1 - 3.4e-85 286.3 0.0 2.3e-63 214.5 0.0 2.0 1 1 1 2 2 2 2 Isocitrate/isopropylmalate dehydrogenase DUF745 PF05335.13 EAQ88040.1 - 0.21 11.3 1.7 0.49 10.1 1.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF745) Transp_cyt_pur PF02133.15 EAQ88041.1 - 1.1e-11 44.3 7.1 1.5e-11 43.7 6.4 1.5 2 0 0 2 2 2 1 Permease for cytosine/purines, uracil, thiamine, allantoin Pro-rich PF15240.6 EAQ88042.1 - 0.25 11.6 26.8 0.27 11.5 26.8 1.1 1 0 0 1 1 1 0 Proline-rich FAD_binding_3 PF01494.19 EAQ88043.1 - 9.9e-18 64.5 0.2 5.2e-17 62.1 0.2 1.9 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EAQ88043.1 - 8.7e-06 25.9 0.2 1.9e-05 24.8 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EAQ88043.1 - 5.7e-05 22.5 0.5 0.017 14.4 0.3 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 EAQ88043.1 - 0.00082 18.5 0.0 0.0016 17.5 0.0 1.4 1 0 0 1 1 1 1 Squalene epoxidase DAO PF01266.24 EAQ88043.1 - 0.001 18.8 2.2 0.013 15.1 1.2 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EAQ88043.1 - 0.0044 16.2 1.3 0.019 14.0 0.6 2.0 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.6 EAQ88043.1 - 0.0099 15.2 0.5 0.26 10.5 0.3 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EAQ88043.1 - 0.073 12.1 0.2 0.1 11.6 0.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A ThiF PF00899.21 EAQ88043.1 - 0.14 11.5 0.4 0.37 10.1 0.2 1.8 2 0 0 2 2 2 0 ThiF family Thi4 PF01946.17 EAQ88043.1 - 0.15 11.3 0.2 0.36 10.0 0.2 1.7 1 0 0 1 1 1 0 Thi4 family 3HCDH_N PF02737.18 EAQ88043.1 - 0.16 11.8 1.2 0.51 10.2 1.2 1.9 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RSN1_TM PF13967.6 EAQ88044.1 - 2.2e-38 131.4 0.2 2.2e-38 131.4 0.2 2.9 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport RSN1_7TM PF02714.15 EAQ88044.1 - 1.3e-37 129.6 24.3 1.3e-32 113.2 5.3 2.6 2 1 1 3 3 3 2 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 EAQ88044.1 - 2.3e-28 99.6 0.1 7.9e-15 55.5 0.2 2.4 2 0 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 EAQ88044.1 - 1.5e-14 53.9 0.0 3.5e-14 52.7 0.0 1.6 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter SOBP PF15279.6 EAQ88046.1 - 0.11 13.1 2.5 0.22 12.1 0.2 2.0 2 0 0 2 2 2 0 Sine oculis-binding protein Hamartin PF04388.12 EAQ88047.1 - 1.9e-18 66.6 0.0 1.9e-18 66.6 0.0 3.5 2 1 1 3 3 3 1 Hamartin protein Spc7 PF08317.11 EAQ88047.1 - 0.27 10.1 35.2 0.45 9.3 16.5 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein Spidroin_N PF16763.5 EAQ88047.1 - 0.94 9.5 6.0 0.99 9.4 4.3 1.8 1 1 0 1 1 1 0 Major ampullate spidroin 1, spider silk protein 1, N-term PapC_N PF13954.6 EAQ88047.1 - 2.8 7.9 6.2 17 5.4 0.1 2.5 1 1 2 3 3 3 0 PapC N-terminal domain UPF0231 PF06062.11 EAQ88047.1 - 4.2 7.7 7.1 4.3 7.6 4.5 2.4 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0231) Fungal_TACC PF12709.7 EAQ88047.1 - 4.3 7.8 11.8 1.1 9.8 1.1 3.8 2 2 1 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins DJ-1_PfpI PF01965.24 EAQ88048.1 - 9.1e-11 41.8 0.0 1.5e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 EAQ88048.1 - 0.048 13.3 0.0 0.069 12.8 0.0 1.2 1 0 0 1 1 1 0 ThiJ/PfpI family-like Fer4_14 PF13394.6 EAQ88048.1 - 0.081 13.1 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S single cluster domain DUF3917 PF13055.6 EAQ88048.1 - 0.16 12.5 0.1 0.37 11.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3917) Ribosomal_L23 PF00276.20 EAQ88049.1 - 1e-11 45.0 0.0 1.9e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L23 Mito_carr PF00153.27 EAQ88050.1 - 2.3e-62 206.9 5.1 1.8e-20 72.7 0.1 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EAQ88050.1 - 0.0078 15.4 0.0 0.42 9.7 0.0 2.4 2 1 0 2 2 2 2 Gammaproteobacterial serine protease SSP160 PF06933.11 EAQ88051.1 - 8.4 4.5 10.8 9.9 4.2 10.8 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 ORC4_C PF14629.6 EAQ88052.1 - 3.1e-62 209.8 0.0 4.7e-62 209.2 0.0 1.3 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.6 EAQ88052.1 - 1.3e-13 51.7 0.0 3.5e-13 50.3 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain PHD_2 PF13831.6 EAQ88052.1 - 3.1e-12 45.8 2.7 6.1e-12 44.9 2.7 1.5 1 0 0 1 1 1 1 PHD-finger PHD PF00628.29 EAQ88052.1 - 2.4e-11 43.3 7.2 4.4e-11 42.5 7.2 1.5 1 0 0 1 1 1 1 PHD-finger AAA PF00004.29 EAQ88052.1 - 9.1e-09 35.8 0.0 2.3e-08 34.5 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 EAQ88052.1 - 9.1e-08 32.2 0.0 2e-07 31.1 0.0 1.5 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 EAQ88052.1 - 1.2e-07 32.0 0.0 2.8e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 EAQ88052.1 - 8.6e-05 22.6 0.0 0.00014 21.8 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea KAP_NTPase PF07693.14 EAQ88052.1 - 0.00012 21.4 0.1 0.00051 19.4 0.0 1.8 1 1 1 2 2 2 1 KAP family P-loop domain NB-ARC PF00931.22 EAQ88052.1 - 0.00014 21.1 0.0 0.00022 20.5 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain Prok-RING_1 PF14446.6 EAQ88052.1 - 0.00032 20.6 3.9 0.00065 19.6 3.9 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 AAA_19 PF13245.6 EAQ88052.1 - 0.00043 20.6 0.1 0.0012 19.2 0.1 1.8 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 EAQ88052.1 - 0.00048 20.2 0.0 0.001 19.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain FYVE_2 PF02318.16 EAQ88052.1 - 0.0019 18.4 0.8 0.004 17.4 0.8 1.5 1 0 0 1 1 1 1 FYVE-type zinc finger TniB PF05621.11 EAQ88052.1 - 0.0019 17.6 0.1 0.34 10.3 0.0 2.2 2 0 0 2 2 2 1 Bacterial TniB protein AAA_30 PF13604.6 EAQ88052.1 - 0.0029 17.4 1.0 0.0044 16.7 0.1 1.8 2 0 0 2 2 1 1 AAA domain ATP-synt_ab PF00006.25 EAQ88052.1 - 0.0033 17.1 0.0 0.0071 16.0 0.0 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain C1_1 PF00130.22 EAQ88052.1 - 0.0038 17.1 0.3 0.0071 16.2 0.3 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) ABC_tran PF00005.27 EAQ88052.1 - 0.0075 16.8 0.0 0.018 15.5 0.0 1.6 1 0 0 1 1 1 1 ABC transporter DUF815 PF05673.13 EAQ88052.1 - 0.0086 15.3 0.0 0.014 14.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RNA_helicase PF00910.22 EAQ88052.1 - 0.013 15.8 0.0 0.03 14.7 0.0 1.6 1 0 0 1 1 1 0 RNA helicase zf-PHD-like PF15446.6 EAQ88052.1 - 0.016 14.8 2.0 0.11 12.1 0.2 2.5 1 1 1 2 2 2 0 PHD/FYVE-zinc-finger like domain PduV-EutP PF10662.9 EAQ88052.1 - 0.016 14.9 0.2 0.076 12.8 0.1 2.0 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 EAQ88052.1 - 0.022 14.3 0.1 0.058 12.9 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_5 PF07728.14 EAQ88052.1 - 0.037 14.0 0.0 0.075 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 EAQ88052.1 - 0.044 14.3 0.2 0.3 11.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EAQ88052.1 - 0.062 13.5 0.2 0.27 11.4 0.0 2.4 2 1 0 2 2 1 0 AAA domain MobB PF03205.14 EAQ88052.1 - 0.087 12.7 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ORC2 PF04084.14 EAQ88052.1 - 0.12 11.3 0.3 3.5 6.5 0.0 2.2 2 0 0 2 2 2 0 Origin recognition complex subunit 2 PIF1 PF05970.14 EAQ88052.1 - 0.13 11.4 0.1 0.24 10.6 0.1 1.3 1 0 0 1 1 1 0 PIF1-like helicase Septin PF00735.18 EAQ88052.1 - 0.14 11.4 0.0 0.24 10.6 0.0 1.2 1 0 0 1 1 1 0 Septin AAA_29 PF13555.6 EAQ88052.1 - 0.15 11.8 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain NTPase_1 PF03266.15 EAQ88052.1 - 0.17 11.8 0.0 0.45 10.4 0.0 1.7 1 0 0 1 1 1 0 NTPase Rad17 PF03215.15 EAQ88052.1 - 0.21 11.5 0.0 0.39 10.6 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain zf-RING_9 PF13901.6 EAQ88052.1 - 0.89 9.5 3.8 1.7 8.6 3.8 1.4 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon C1_2 PF03107.16 EAQ88052.1 - 4.9 7.5 6.9 0.85 10.0 2.6 1.9 2 0 0 2 2 1 0 C1 domain Glyco_hydro_18 PF00704.28 EAQ88055.1 - 3.9e-47 161.5 0.1 5e-47 161.1 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 PhoLip_ATPase_N PF16209.5 EAQ88055.1 - 0.2 11.4 0.1 0.74 9.6 0.0 1.9 2 0 0 2 2 2 0 Phospholipid-translocating ATPase N-terminal Chitin_bind_1 PF00187.19 EAQ88055.1 - 2.5 8.7 11.1 0.23 12.0 5.1 2.4 2 1 0 2 2 2 0 Chitin recognition protein RGS PF00615.19 EAQ88058.1 - 3.1e-38 130.6 0.6 1.6e-37 128.4 0.0 2.4 3 0 0 3 3 3 1 Regulator of G protein signaling domain DEP PF00610.21 EAQ88058.1 - 1.9e-22 79.1 0.0 2.5e-18 65.9 0.1 3.5 3 0 0 3 3 3 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Replic_Relax PF13814.6 EAQ88058.1 - 0.035 14.2 0.0 0.33 11.0 0.0 2.2 2 0 0 2 2 2 0 Replication-relaxation NMT PF01233.19 EAQ88058.1 - 0.05 13.4 0.0 0.095 12.5 0.0 1.4 1 0 0 1 1 1 0 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain HTH_3 PF01381.22 EAQ88058.1 - 0.082 13.0 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix Pkinase PF00069.25 EAQ88059.1 - 1e-07 31.6 0.0 1.4e-07 31.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ88059.1 - 4.5e-05 22.9 0.0 6.6e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EAQ88059.1 - 0.0002 20.8 0.1 0.00037 19.9 0.0 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF5345 PF17280.2 EAQ88060.1 - 0.059 13.3 2.5 0.095 12.7 0.3 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5345) Sporozoite_P67 PF05642.11 EAQ88060.1 - 0.099 10.7 15.5 0.025 12.7 12.4 1.4 1 1 0 1 1 1 0 Sporozoite P67 surface antigen DUF3915 PF13054.6 EAQ88060.1 - 1.8 8.5 7.3 0.59 10.1 4.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) CDC73_C PF05179.14 EAQ88061.1 - 1.7e-54 183.7 0.0 2.5e-54 183.2 0.0 1.2 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal Bystin PF05291.11 EAQ88062.1 - 1.3e-100 336.5 0.1 4.4e-93 311.8 0.0 2.1 1 1 1 2 2 2 2 Bystin DUF383 PF04063.14 EAQ88063.1 - 8.2e-60 201.7 0.1 1.7e-59 200.7 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF383) DUF384 PF04064.13 EAQ88063.1 - 5.8e-25 86.9 0.4 1e-24 86.1 0.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF384) Sugar_tr PF00083.24 EAQ88064.1 - 3.6e-47 161.2 16.9 4.8e-47 160.9 16.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EAQ88064.1 - 5.3e-20 71.6 24.8 7.8e-20 71.1 24.8 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily tRNA-Thr_ED PF08915.11 EAQ88064.1 - 0.13 12.3 0.0 0.3 11.2 0.0 1.5 1 0 0 1 1 1 0 Archaea-specific editing domain of threonyl-tRNA synthetase Fungal_trans PF04082.18 EAQ88065.1 - 2.2e-26 92.5 0.0 4.3e-26 91.5 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EAQ88065.1 - 4e-09 36.5 9.4 6.4e-09 35.8 9.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2457 PF10446.9 EAQ88065.1 - 8 5.5 5.7 15 4.6 5.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) MFS_1 PF07690.16 EAQ88066.1 - 4.4e-25 88.3 23.1 2.1e-16 59.8 3.5 3.1 1 1 2 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.24 EAQ88066.1 - 4.4e-08 32.4 1.3 4.4e-08 32.4 1.3 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.7 EAQ88066.1 - 0.018 13.9 5.0 0.009 14.9 0.4 2.5 1 1 1 2 2 2 0 MFS_1 like family Ccdc124 PF06244.12 EAQ88070.1 - 1.1e-28 100.4 16.5 1.1e-28 100.4 16.5 2.5 2 1 0 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 UQ_con PF00179.26 EAQ88071.1 - 1.7e-08 34.2 0.0 2.9e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme SPX PF03105.19 EAQ88071.1 - 7.8 6.3 14.5 14 5.5 14.5 1.4 1 0 0 1 1 1 0 SPX domain 2OG-FeII_Oxy_2 PF13532.6 EAQ88072.1 - 1.1e-38 133.4 0.1 1.5e-38 133.0 0.1 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-GRF PF06839.12 EAQ88072.1 - 4.6e-10 39.4 2.6 9e-10 38.5 2.6 1.5 1 0 0 1 1 1 1 GRF zinc finger CUE PF02845.16 EAQ88072.1 - 0.037 13.7 0.0 0.087 12.6 0.0 1.6 1 0 0 1 1 1 0 CUE domain WD40 PF00400.32 EAQ88073.1 - 1.9e-19 69.6 12.8 0.001 19.8 0.0 6.6 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAQ88073.1 - 0.00053 20.2 0.0 2.3 8.6 0.0 3.6 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Helicase_C PF00271.31 EAQ88074.1 - 7.8e-22 77.7 0.0 1.7e-21 76.6 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EAQ88074.1 - 6.3e-17 61.9 0.0 2.1e-16 60.2 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 EAQ88074.1 - 0.15 11.3 0.0 0.23 10.6 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase cobW PF02492.19 EAQ88076.1 - 2.5e-27 95.6 0.1 3.9e-27 95.0 0.1 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain NOT2_3_5 PF04153.18 EAQ88076.1 - 1.6e-24 86.5 0.5 4.1e-24 85.1 0.5 1.6 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family CUE PF02845.16 EAQ88076.1 - 6e-10 38.6 0.0 1.2e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 CUE domain SUIM_assoc PF16619.5 EAQ88076.1 - 0.16 12.0 15.2 1 9.5 4.0 2.9 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 EAQ88076.1 - 1 8.9 7.0 4.5 6.8 2.1 2.4 2 0 0 2 2 2 0 Spt20 family Mob1_phocein PF03637.17 EAQ88077.1 - 2.3e-22 79.8 0.0 3.4e-22 79.2 0.0 1.2 1 0 0 1 1 1 1 Mob1/phocein family Fungal_trans_2 PF11951.8 EAQ88078.1 - 4.7e-14 52.0 0.3 3.4e-13 49.2 0.3 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EAQ88078.1 - 9.8e-07 28.8 11.7 1.7e-06 28.1 11.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PhoD_N PF16655.5 EAQ88078.1 - 0.12 12.9 0.0 0.29 11.7 0.0 1.6 1 0 0 1 1 1 0 PhoD-like phosphatase, N-terminal domain MOSC PF03473.17 EAQ88081.1 - 1.9e-21 76.4 0.0 3e-21 75.8 0.0 1.3 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 EAQ88081.1 - 3.9e-11 42.9 0.0 1e-10 41.5 0.0 1.7 2 0 0 2 2 2 1 MOSC N-terminal beta barrel domain RCDG1 PF15725.5 EAQ88081.1 - 0.1 13.1 3.7 0.4 11.1 3.7 2.0 1 0 0 1 1 1 0 Renal cancer differentiation gene 1 protein NapE PF06796.11 EAQ88081.1 - 0.38 10.3 0.0 0.38 10.3 0.0 2.3 3 0 0 3 3 3 0 Periplasmic nitrate reductase protein NapE SMC_N PF02463.19 EAQ88082.1 - 1.9e-68 230.2 18.8 1.2e-38 132.7 0.5 3.2 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 EAQ88082.1 - 1.5e-20 73.6 0.2 1.5e-20 73.6 0.2 2.5 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 EAQ88082.1 - 2.2e-11 44.1 1.0 0.00013 21.9 0.1 3.1 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EAQ88082.1 - 8.9e-09 36.1 29.7 8.9e-09 36.1 29.7 5.9 2 2 2 4 4 4 1 AAA domain AAA_29 PF13555.6 EAQ88082.1 - 0.00013 21.6 0.1 0.0003 20.5 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Lipase_GDSL PF00657.22 EAQ88082.1 - 0.096 12.7 4.3 0.98 9.4 0.1 3.4 4 0 0 4 4 4 0 GDSL-like Lipase/Acylhydrolase LysM PF01476.20 EAQ88083.1 - 0.18 11.9 0.0 0.3 11.2 0.0 1.4 1 0 0 1 1 1 0 LysM domain Arv1 PF04161.13 EAQ88084.1 - 6.6e-64 215.9 0.3 3.7e-61 207.0 0.3 2.1 1 1 0 1 1 1 1 Arv1-like family TraI PF07057.11 EAQ88084.1 - 0.16 12.1 0.1 0.26 11.4 0.1 1.3 1 0 0 1 1 1 0 DNA helicase TraI ATP_synt_H PF05493.13 EAQ88085.1 - 4.6e-24 84.7 1.3 5.1e-24 84.5 1.3 1.0 1 0 0 1 1 1 1 ATP synthase subunit H DUF4131 PF13567.6 EAQ88085.1 - 0.013 15.2 1.1 0.014 15.0 1.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) YfhO PF09586.10 EAQ88085.1 - 0.027 12.7 0.2 0.027 12.7 0.2 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Ost5 PF05251.12 EAQ88085.1 - 0.092 13.0 2.3 0.13 12.6 2.3 1.2 1 0 0 1 1 1 0 Oligosaccharyltransferase subunit 5 VIT1 PF01988.19 EAQ88085.1 - 0.16 11.8 0.8 0.17 11.7 0.8 1.0 1 0 0 1 1 1 0 VIT family ABC2_membrane_2 PF12679.7 EAQ88085.1 - 0.17 11.1 2.9 0.22 10.8 2.9 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein CD20 PF04103.15 EAQ88085.1 - 0.26 11.4 4.1 0.29 11.2 4.1 1.1 1 0 0 1 1 1 0 CD20-like family TctB PF07331.11 EAQ88085.1 - 0.28 11.5 4.4 0.34 11.2 4.4 1.1 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family DUF4307 PF14155.6 EAQ88085.1 - 0.89 9.4 2.4 0.64 9.9 0.8 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4307) NAD_binding_2 PF03446.15 EAQ88086.1 - 1.3e-22 80.7 0.4 2.2e-22 79.9 0.4 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 EAQ88086.1 - 2.5e-09 37.4 0.0 4.3e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Shikimate_DH PF01488.20 EAQ88086.1 - 0.0013 18.8 2.1 0.0014 18.6 0.4 1.9 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase BAR_2 PF10455.9 EAQ88087.1 - 1.2e-56 191.9 0.0 1.8e-56 191.4 0.0 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 EAQ88087.1 - 9.2e-22 77.8 1.5 1.3e-20 74.0 1.6 2.1 1 1 0 1 1 1 1 BAR domain BAR_3 PF16746.5 EAQ88087.1 - 0.0041 16.8 0.1 0.026 14.2 0.0 2.1 2 0 0 2 2 2 1 BAR domain of APPL family Ribosomal_60s PF00428.19 EAQ88087.1 - 3.3 8.4 7.8 28 5.4 0.2 2.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein LSM PF01423.22 EAQ88088.1 - 3.8e-16 58.5 0.0 4.8e-16 58.2 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EAQ88088.1 - 0.083 13.0 0.0 0.1 12.8 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain PPR PF01535.20 EAQ88089.1 - 7.9e-11 41.5 1.4 1.5 9.2 0.0 6.5 6 0 0 6 6 6 4 PPR repeat PPR_2 PF13041.6 EAQ88089.1 - 1.7e-10 40.9 0.0 0.048 13.9 0.0 7.7 9 0 0 9 9 9 2 PPR repeat family PPR_long PF17177.4 EAQ88089.1 - 4.6e-09 36.0 0.0 0.00034 20.1 0.0 4.1 4 0 0 4 4 4 2 Pentacotripeptide-repeat region of PRORP PPR_3 PF13812.6 EAQ88089.1 - 2e-08 34.2 0.0 0.0014 18.6 0.0 3.5 4 0 0 4 4 4 2 Pentatricopeptide repeat domain PPR_1 PF12854.7 EAQ88089.1 - 0.0066 16.1 0.0 19 5.0 0.0 4.0 4 0 0 4 4 4 2 PPR repeat DUF4733 PF15878.5 EAQ88089.1 - 0.069 13.6 0.0 0.24 11.9 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4733) NMT1_3 PF16868.5 EAQ88089.1 - 0.12 11.8 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 NMT1-like family MFS_1 PF07690.16 EAQ88090.1 - 2.7e-29 102.2 25.5 1.5e-22 80.0 10.9 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EAQ88090.1 - 1.7e-08 33.8 1.1 1.7e-08 33.8 1.1 2.4 3 0 0 3 3 3 1 Sugar (and other) transporter DUF1751 PF08551.10 EAQ88090.1 - 0.017 15.7 0.4 0.017 15.7 0.4 2.7 3 0 0 3 3 3 0 Eukaryotic integral membrane protein (DUF1751) BRD4_CDT PF17105.5 EAQ88090.1 - 0.47 10.1 2.3 0.61 9.7 0.7 1.9 2 0 0 2 2 2 0 C-terminal domain of bromodomain protein 4 HIT PF01230.23 EAQ88091.1 - 5.2e-21 75.2 0.1 8.2e-21 74.6 0.1 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 EAQ88091.1 - 0.0032 17.9 0.0 2.3 8.7 0.0 2.1 2 0 0 2 2 2 2 Scavenger mRNA decapping enzyme C-term binding Fungal_trans PF04082.18 EAQ88092.1 - 6.8e-41 140.1 0.0 1.1e-40 139.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EAQ88092.1 - 2.5e-08 33.9 7.0 5.4e-08 32.8 7.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ferrochelatase PF00762.19 EAQ88093.1 - 2.8e-98 328.9 0.0 3.2e-98 328.7 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase Ku_N PF03731.15 EAQ88094.1 - 2e-34 119.3 0.0 2.7e-34 118.8 0.0 1.2 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku PF02735.16 EAQ88094.1 - 1.9e-30 106.1 0.0 2e-20 73.4 0.0 2.5 1 1 1 2 2 2 2 Ku70/Ku80 beta-barrel domain Ku_C PF03730.14 EAQ88094.1 - 1.8e-27 95.8 0.3 1.8e-27 95.8 0.3 2.5 3 0 0 3 3 3 1 Ku70/Ku80 C-terminal arm SAP PF02037.27 EAQ88094.1 - 5.6e-11 41.9 0.1 1.2e-09 37.6 0.2 2.3 2 0 0 2 2 2 1 SAP domain HeH PF12949.7 EAQ88094.1 - 0.00032 20.4 0.7 0.00093 18.9 0.7 1.9 1 0 0 1 1 1 1 HeH/LEM domain VWA_2 PF13519.6 EAQ88094.1 - 0.05 14.2 0.0 0.38 11.4 0.0 2.4 2 0 0 2 2 2 0 von Willebrand factor type A domain Zn_clus PF00172.18 EAQ88095.1 - 0.00012 22.2 7.8 0.00022 21.3 7.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain La PF05383.17 EAQ88096.1 - 5.5e-22 77.6 0.0 8.9e-22 76.9 0.0 1.3 1 0 0 1 1 1 1 La domain S4 PF01479.25 EAQ88097.1 - 3.1e-16 58.8 0.0 6.1e-16 57.9 0.0 1.5 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.6 EAQ88097.1 - 0.0081 16.0 0.0 0.029 14.2 0.0 1.9 2 0 0 2 2 2 1 S4 domain Septin PF00735.18 EAQ88098.1 - 7.4e-120 399.5 0.3 7.4e-120 399.5 0.3 1.7 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 EAQ88098.1 - 1.9e-08 34.3 0.6 4.5e-08 33.2 0.0 2.0 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EAQ88098.1 - 1.8e-06 27.6 1.0 0.00013 21.5 0.0 2.8 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EAQ88098.1 - 2e-05 24.5 3.5 0.0016 18.3 0.9 3.3 2 1 0 2 2 2 1 RsgA GTPase ABC_tran PF00005.27 EAQ88098.1 - 0.00038 21.0 2.9 0.018 15.6 0.0 2.6 2 1 0 2 2 2 1 ABC transporter Roc PF08477.13 EAQ88098.1 - 0.00047 20.4 0.0 0.0012 19.1 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AIG1 PF04548.16 EAQ88098.1 - 0.00064 19.1 0.8 0.0013 18.1 0.0 1.9 2 0 0 2 2 2 1 AIG1 family AAA_16 PF13191.6 EAQ88098.1 - 0.0015 18.9 0.0 0.0043 17.4 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain Ras PF00071.22 EAQ88098.1 - 0.0049 16.5 0.0 0.03 13.9 0.0 2.3 2 0 0 2 2 2 1 Ras family AAA_22 PF13401.6 EAQ88098.1 - 0.0065 16.7 0.9 0.024 14.9 0.1 2.4 2 2 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EAQ88098.1 - 0.011 15.4 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Dynamin_N PF00350.23 EAQ88098.1 - 0.013 15.6 6.3 0.75 9.8 0.0 3.9 4 1 0 4 4 4 0 Dynamin family RNA_helicase PF00910.22 EAQ88098.1 - 0.023 15.1 0.9 0.38 11.1 0.0 2.6 3 0 0 3 3 2 0 RNA helicase FtsK_SpoIIIE PF01580.18 EAQ88098.1 - 0.038 13.3 0.0 0.11 11.8 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_24 PF13479.6 EAQ88098.1 - 0.059 13.1 0.0 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 EAQ88098.1 - 0.072 12.8 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_7 PF12775.7 EAQ88098.1 - 0.079 12.5 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Strep_SA_rep PF06696.11 EAQ88098.1 - 0.15 12.1 0.6 0.34 10.9 0.6 1.5 1 0 0 1 1 1 0 Streptococcal surface antigen repeat ATP_bind_1 PF03029.17 EAQ88098.1 - 0.25 11.1 5.6 1.9 8.2 0.1 3.2 2 1 0 3 3 3 0 Conserved hypothetical ATP binding protein AP1AR PF15745.5 EAQ88098.1 - 0.44 10.1 8.9 0.94 9.0 8.9 1.5 1 0 0 1 1 1 0 AP-1 complex-associated regulatory protein Exonuc_VII_L PF02601.15 EAQ88098.1 - 0.94 9.0 6.6 1.4 8.4 6.6 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF3987 PF13148.6 EAQ88098.1 - 1.6 7.7 0.0 1.6 7.7 0.0 2.4 2 1 0 2 2 1 0 Protein of unknown function (DUF3987) DUF87 PF01935.17 EAQ88098.1 - 2.2 8.3 5.3 3.5 7.7 0.0 2.6 3 0 0 3 3 2 0 Helicase HerA, central domain Atg14 PF10186.9 EAQ88098.1 - 8.3 5.4 9.6 12 4.8 9.6 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 PLA2_B PF01735.18 EAQ88099.1 - 4.3e-29 101.3 0.0 8e-29 100.4 0.0 1.4 1 1 0 1 1 1 1 Lysophospholipase catalytic domain Patatin PF01734.22 EAQ88099.1 - 0.15 12.2 1.1 5.9 7.0 0.2 2.5 2 0 0 2 2 2 0 Patatin-like phospholipase Ribonucleas_3_3 PF14622.6 EAQ88100.1 - 0.0022 18.2 0.0 0.0028 17.8 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.26 EAQ88100.1 - 0.027 15.2 0.0 0.045 14.5 0.0 1.3 1 0 0 1 1 1 0 Double-stranded RNA binding motif Metallophos PF00149.28 EAQ88102.1 - 4.3e-05 24.1 0.0 4.6e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Cyclin_N PF00134.23 EAQ88103.1 - 0.0016 18.2 0.1 0.055 13.2 0.0 2.1 2 0 0 2 2 2 2 Cyclin, N-terminal domain COA2 PF17051.5 EAQ88107.1 - 1e-05 25.5 0.0 1.4e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome C oxidase assembly factor 2 Endosulfine PF04667.17 EAQ88107.1 - 0.057 13.6 0.0 0.13 12.4 0.0 1.6 2 0 0 2 2 2 0 cAMP-regulated phosphoprotein/endosulfine conserved region OTCace_N PF02729.21 EAQ88108.1 - 3.3e-45 153.7 0.0 7.4e-45 152.6 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.24 EAQ88108.1 - 4.4e-30 104.8 0.0 1.2e-29 103.4 0.0 1.8 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain CPSase_L_D2 PF02786.17 EAQ88108.1 - 5.4e-28 97.9 0.1 8.4e-28 97.3 0.1 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain MGS PF02142.22 EAQ88108.1 - 1.5e-21 76.4 0.0 6.3e-21 74.4 0.0 2.2 2 0 0 2 2 2 1 MGS-like domain ATP-grasp PF02222.22 EAQ88108.1 - 1.1e-10 41.3 0.1 2e-10 40.5 0.1 1.4 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 EAQ88108.1 - 6.2e-10 38.9 0.1 1.5e-09 37.7 0.1 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 EAQ88108.1 - 1.1e-05 25.2 0.0 3.8e-05 23.4 0.0 1.9 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon RimK PF08443.11 EAQ88108.1 - 0.0026 17.4 0.0 0.0058 16.2 0.0 1.7 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.14 EAQ88108.1 - 0.0032 17.5 0.1 0.0074 16.3 0.1 1.7 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 EAQ88108.1 - 0.047 13.5 0.0 0.15 11.9 0.0 1.8 1 1 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain DUF992 PF06186.11 EAQ88108.1 - 0.05 13.4 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF992) CPSase_L_D2 PF02786.17 EAQ88109.1 - 1.5e-84 282.8 0.0 2.1e-84 282.2 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.22 EAQ88109.1 - 7.8e-46 155.1 0.0 1.5e-45 154.2 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 EAQ88109.1 - 1.3e-45 155.5 0.0 2.3e-45 154.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_L_D3 PF02787.19 EAQ88109.1 - 8.1e-40 136.0 0.0 1.9e-39 134.8 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain Dala_Dala_lig_C PF07478.13 EAQ88109.1 - 3.4e-07 30.0 0.1 7.1e-07 29.0 0.1 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 EAQ88109.1 - 7.5e-06 25.6 0.0 1.4e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Peptidase_C26 PF07722.13 EAQ88109.1 - 1.7e-05 24.7 0.2 0.0029 17.4 0.3 2.4 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.24 EAQ88109.1 - 0.0012 18.7 0.0 0.065 13.0 0.0 2.6 2 0 0 2 2 2 1 DJ-1/PfpI family ATP-grasp_3 PF02655.14 EAQ88109.1 - 0.16 12.0 0.1 0.56 10.2 0.0 2.0 2 0 0 2 2 2 0 ATP-grasp domain RskA PF10099.9 EAQ88111.1 - 0.084 13.2 0.0 0.096 13.0 0.0 1.0 1 0 0 1 1 1 0 Anti-sigma-K factor rskA TAP42 PF04177.12 EAQ88113.1 - 5.6e-109 364.1 0.0 6.4e-109 363.9 0.0 1.0 1 0 0 1 1 1 1 TAP42-like family KBP_C PF12309.8 EAQ88113.1 - 0.11 12.0 0.1 0.15 11.6 0.1 1.3 1 0 0 1 1 1 0 KIF-1 binding protein C terminal PNP_phzG_C PF10590.9 EAQ88114.1 - 7.3e-22 77.2 2.0 3.5e-21 75.0 2.0 2.2 2 0 0 2 2 2 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Putative_PNPOx PF01243.20 EAQ88114.1 - 4.5e-12 46.0 0.0 2.3e-11 43.7 0.0 2.0 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxase_2 PF12766.7 EAQ88114.1 - 0.13 12.9 0.0 0.26 11.9 0.0 1.5 1 1 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase Ribonuclease_3 PF00636.26 EAQ88115.1 - 3.9e-28 98.1 0.4 9.6e-18 64.7 0.0 4.2 3 1 1 4 4 4 3 Ribonuclease III domain Dicer_dimer PF03368.14 EAQ88115.1 - 2.3e-21 75.7 0.5 3.7e-20 71.9 0.1 2.9 3 0 0 3 3 3 1 Dicer dimerisation domain Ribonucleas_3_3 PF14622.6 EAQ88115.1 - 1.8e-18 66.9 0.0 3.1e-09 37.0 0.0 3.7 3 0 0 3 3 3 2 Ribonuclease-III-like Helicase_C PF00271.31 EAQ88115.1 - 2.4e-15 56.8 0.0 5.6e-15 55.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EAQ88115.1 - 8.2e-05 22.7 0.0 0.00057 19.9 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAQ88115.1 - 0.0077 16.0 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 EAQ88115.1 - 0.029 13.6 0.0 0.059 12.6 0.0 1.4 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase dsrm PF00035.26 EAQ88115.1 - 0.082 13.6 0.4 10 6.9 0.1 2.7 2 0 0 2 2 2 0 Double-stranded RNA binding motif Peptidase_C12 PF01088.21 EAQ88117.1 - 4.7e-51 173.5 0.0 5.6e-51 173.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 SUV3_C PF12513.8 EAQ88118.1 - 1.7e-17 63.1 0.7 3.4e-17 62.1 0.7 1.6 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Suv3_C_1 PF18147.1 EAQ88118.1 - 1.4e-11 44.0 0.0 2.8e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Suv3 C-terminal domain 1 Helicase_C PF00271.31 EAQ88118.1 - 3.4e-08 33.8 0.0 7.4e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain TK PF00265.18 EAQ88118.1 - 0.13 12.1 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Thymidine kinase Synaptobrevin PF00957.21 EAQ88119.1 - 2.5e-29 100.9 0.1 3.4e-29 100.5 0.1 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 EAQ88119.1 - 7e-29 99.7 0.0 1.1e-28 99.1 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Holin_BlyA PF05102.12 EAQ88119.1 - 0.089 12.8 1.7 0.15 12.0 1.7 1.3 1 0 0 1 1 1 0 holin, BlyA family adh_short PF00106.25 EAQ88120.1 - 3.8e-15 55.9 0.1 1.4e-13 50.8 0.0 2.8 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 EAQ88120.1 - 2.5e-06 27.5 0.3 2.3e-05 24.4 0.0 2.2 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.6 EAQ88120.1 - 3.1e-06 26.9 0.0 9.9e-06 25.3 0.0 1.8 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 EAQ88120.1 - 3.8e-05 23.3 0.0 8.5e-05 22.1 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Med8 PF10232.9 EAQ88120.1 - 0.0088 15.7 2.2 0.013 15.1 2.2 1.2 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 E1-N PF14463.6 EAQ88120.1 - 0.028 14.2 0.3 0.16 11.8 0.2 2.2 1 1 1 2 2 2 0 E1 N-terminal domain G-patch PF01585.23 EAQ88121.1 - 1.7e-08 34.2 0.1 3e-08 33.4 0.1 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 EAQ88121.1 - 0.02 14.9 0.1 0.2 11.8 0.1 2.3 2 0 0 2 2 2 0 G-patch domain Sec63 PF02889.16 EAQ88122.1 - 1.9e-132 440.1 0.0 4.6e-79 265.2 0.2 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 EAQ88122.1 - 3.3e-49 167.0 0.0 1.7e-25 89.8 0.3 2.9 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.15 EAQ88122.1 - 3.7e-22 79.1 0.0 3.7e-11 43.3 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EAQ88122.1 - 3.7e-15 56.2 0.1 2.3e-06 27.9 0.0 4.2 3 2 0 3 3 3 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 EAQ88122.1 - 7.1e-07 29.6 0.5 0.054 13.8 0.0 3.5 2 2 0 2 2 2 2 AAA domain AAA_30 PF13604.6 EAQ88122.1 - 1.2e-05 25.1 0.1 0.21 11.3 0.2 2.6 2 0 0 2 2 2 2 AAA domain Helicase_PWI PF18149.1 EAQ88122.1 - 1.4e-05 25.2 0.0 3.8e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 N-terminal helicase PWI domain AAA_19 PF13245.6 EAQ88122.1 - 0.00028 21.2 0.3 0.024 15.0 0.3 2.7 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 EAQ88122.1 - 0.0016 18.9 2.3 2.1 8.8 0.0 4.8 4 2 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 EAQ88122.1 - 0.057 12.5 0.1 2.6 7.1 0.0 2.7 3 0 0 3 3 3 0 Type II/IV secretion system protein TniB PF05621.11 EAQ88122.1 - 0.066 12.6 0.4 20 4.5 0.1 3.9 4 0 0 4 4 4 0 Bacterial TniB protein Ras PF00071.22 EAQ88123.1 - 8.4e-65 217.3 0.1 9.9e-65 217.1 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAQ88123.1 - 9.3e-34 116.2 0.0 1.4e-33 115.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAQ88123.1 - 2.4e-13 49.9 0.0 2.9e-13 49.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EAQ88123.1 - 4.9e-06 26.2 0.0 1.1e-05 25.1 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EAQ88123.1 - 0.00024 20.5 0.0 0.00026 20.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EAQ88123.1 - 0.0021 18.0 0.3 2 8.3 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EAQ88123.1 - 0.004 17.2 0.0 0.0064 16.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 EAQ88123.1 - 0.02 14.3 0.0 0.025 14.0 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 EAQ88123.1 - 0.054 13.0 0.0 0.26 10.8 0.0 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_22 PF13401.6 EAQ88123.1 - 0.13 12.5 0.1 0.49 10.7 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EAQ88123.1 - 0.15 11.5 0.0 0.42 10.1 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region NCA2 PF08637.10 EAQ88124.1 - 1.2e-109 365.9 0.4 1.9e-109 365.3 0.4 1.3 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 FA_hydroxylase PF04116.13 EAQ88125.1 - 1.2e-17 64.5 18.0 2.8e-11 43.9 4.1 2.8 2 1 1 3 3 3 2 Fatty acid hydroxylase superfamily Pterin_4a PF01329.19 EAQ88126.1 - 5.7e-22 77.7 0.0 7.9e-22 77.3 0.0 1.2 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase bZIP_1 PF00170.21 EAQ88127.1 - 0.95 9.6 5.9 12 6.1 5.9 2.1 1 1 0 1 1 1 0 bZIP transcription factor Actin PF00022.19 EAQ88128.1 - 2.3e-47 161.5 0.0 1.5e-32 112.7 0.0 2.4 2 1 0 2 2 2 2 Actin Pkinase PF00069.25 EAQ88129.1 - 7.2e-05 22.3 0.1 0.00012 21.5 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ88129.1 - 0.0036 16.6 0.0 0.0058 15.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PIP49_C PF12260.8 EAQ88129.1 - 0.041 13.5 0.0 0.06 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 YL1_C PF08265.11 EAQ88130.1 - 2.6e-15 55.9 0.1 3.9e-15 55.3 0.1 1.3 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Got1 PF04178.12 EAQ88131.1 - 1e-15 58.1 10.5 1.3e-15 57.8 10.5 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family Profilin PF00235.19 EAQ88132.1 - 3.1e-39 134.1 0.6 3.5e-39 134.0 0.6 1.0 1 0 0 1 1 1 1 Profilin DUF3948 PF13134.6 EAQ88133.1 - 8.2 6.2 6.8 5.7 6.7 1.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3948) AAA PF00004.29 EAQ88134.1 - 3.4e-53 179.6 0.0 1.4e-38 132.3 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EAQ88134.1 - 5.8e-15 54.8 0.2 1.6e-10 40.6 0.1 2.8 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 EAQ88134.1 - 9.8e-08 32.6 0.1 0.00039 20.8 0.1 3.3 2 1 1 3 3 3 2 AAA ATPase domain AAA_28 PF13521.6 EAQ88134.1 - 8.3e-05 22.9 0.1 0.0054 17.0 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_5 PF07728.14 EAQ88134.1 - 0.00016 21.7 0.0 0.06 13.3 0.0 3.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EAQ88134.1 - 0.00074 19.3 0.0 0.1 12.3 0.0 2.6 3 0 0 3 3 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 EAQ88134.1 - 0.0039 16.8 3.6 5 6.7 0.0 4.3 2 2 2 4 4 4 1 AAA domain RNA_helicase PF00910.22 EAQ88134.1 - 0.004 17.5 0.0 5.7 7.4 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_14 PF13173.6 EAQ88134.1 - 0.0042 17.1 0.0 2.4 8.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EAQ88134.1 - 0.0069 16.6 0.0 3.8 7.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain Vps4_C PF09336.10 EAQ88134.1 - 0.0095 15.9 0.0 0.054 13.5 0.0 2.3 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_2 PF07724.14 EAQ88134.1 - 0.0095 16.1 0.0 0.17 12.0 0.0 2.9 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 EAQ88134.1 - 0.016 15.4 8.3 1.8 8.8 0.4 4.8 4 1 1 5 5 5 0 AAA domain AFG1_ATPase PF03969.16 EAQ88134.1 - 0.021 13.7 0.0 0.1 11.5 0.0 2.1 2 0 0 2 2 2 0 AFG1-like ATPase NACHT PF05729.12 EAQ88134.1 - 0.041 13.8 4.8 0.28 11.1 0.6 3.2 2 1 1 3 3 3 0 NACHT domain ABC_tran PF00005.27 EAQ88134.1 - 0.051 14.1 0.0 0.16 12.5 0.0 1.8 2 0 0 2 2 2 0 ABC transporter Mg_chelatase PF01078.21 EAQ88134.1 - 0.057 12.8 1.4 0.82 9.0 0.1 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 EAQ88134.1 - 0.057 13.1 0.0 9.4 5.9 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein Rad17 PF03215.15 EAQ88134.1 - 0.06 13.3 0.0 0.23 11.4 0.0 1.9 2 0 0 2 2 2 0 Rad17 P-loop domain TIP49 PF06068.13 EAQ88134.1 - 0.14 11.4 0.1 3.7 6.7 0.0 2.5 3 0 0 3 3 3 0 TIP49 P-loop domain AAA_7 PF12775.7 EAQ88134.1 - 0.27 10.7 0.5 29 4.1 0.0 2.7 3 0 0 3 3 3 0 P-loop containing dynein motor region ATPase PF06745.13 EAQ88134.1 - 0.29 10.4 2.2 1.1 8.6 0.2 2.5 3 0 0 3 3 3 0 KaiC Bac_DnaA PF00308.18 EAQ88134.1 - 1.4 8.7 2.8 5.6 6.7 1.8 2.3 2 1 0 2 2 1 0 Bacterial dnaA protein SMK-1 PF04802.15 EAQ88135.1 - 5.7e-81 270.9 0.6 5.7e-81 270.9 0.6 1.8 2 0 0 2 2 2 1 Component of IIS longevity pathway SMK-1 Ribosomal_60s PF00428.19 EAQ88135.1 - 0.011 16.3 10.7 0.018 15.6 8.8 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF3402 PF11882.8 EAQ88135.1 - 0.059 12.5 0.1 0.059 12.5 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3402) TFIIA PF03153.13 EAQ88135.1 - 1.9 8.4 10.2 0.3 11.0 1.3 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit SUIM_assoc PF16619.5 EAQ88135.1 - 2.3 8.3 11.2 0.4 10.8 5.3 2.7 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Glycos_transf_2 PF00535.26 EAQ88138.1 - 1.8e-23 83.2 0.0 2e-19 70.0 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EAQ88138.1 - 1.3e-08 35.0 0.0 3.2e-06 27.2 0.0 2.2 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 EAQ88138.1 - 0.087 12.3 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase like family 2 SE PF08491.10 EAQ88139.1 - 4.3e-82 275.3 0.0 6.8e-82 274.6 0.0 1.3 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.19 EAQ88139.1 - 1.9e-13 50.4 0.0 4.1e-13 49.3 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 EAQ88139.1 - 2.9e-09 37.0 0.3 1.1e-06 28.4 0.1 2.6 2 1 1 3 3 3 2 FAD dependent oxidoreductase GIDA PF01134.22 EAQ88139.1 - 3.7e-06 26.3 0.0 8.2e-05 21.9 0.1 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 EAQ88139.1 - 5.9e-06 25.9 0.3 2.9e-05 23.6 0.1 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EAQ88139.1 - 3.7e-05 23.9 0.2 8.1e-05 22.8 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EAQ88139.1 - 8.7e-05 21.8 0.3 0.00014 21.1 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 EAQ88139.1 - 0.00093 18.5 0.0 0.0017 17.6 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 EAQ88139.1 - 0.0015 17.9 0.1 0.0027 17.0 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 EAQ88139.1 - 0.0092 15.6 0.1 0.016 14.9 0.1 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.27 EAQ88139.1 - 0.011 16.3 0.3 0.028 15.0 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EAQ88139.1 - 0.044 12.5 0.1 0.061 12.0 0.1 1.1 1 0 0 1 1 1 0 HI0933-like protein Shikimate_DH PF01488.20 EAQ88139.1 - 0.072 13.2 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_Gly3P_dh_N PF01210.23 EAQ88139.1 - 0.078 13.0 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Trp_halogenase PF04820.14 EAQ88139.1 - 0.08 11.8 0.1 1 8.2 0.1 2.3 3 0 0 3 3 3 0 Tryptophan halogenase Lycopene_cycl PF05834.12 EAQ88139.1 - 0.091 11.8 0.4 1.2 8.1 0.1 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein ANTAR PF03861.14 EAQ88140.1 - 0.39 10.6 6.6 1.5 8.7 6.6 2.1 1 0 0 1 1 1 0 ANTAR domain Peptidase_S26 PF10502.9 EAQ88142.1 - 3.9e-05 23.5 0.0 0.00067 19.5 0.0 2.0 1 1 1 2 2 2 1 Signal peptidase, peptidase S26 Peptidase_S24 PF00717.23 EAQ88142.1 - 0.0023 17.8 0.0 0.0036 17.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like EIF_2_alpha PF07541.12 EAQ88143.1 - 5e-36 123.3 0.0 9.3e-36 122.4 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 EAQ88143.1 - 9e-14 51.6 0.7 1.5e-13 50.8 0.7 1.4 1 0 0 1 1 1 1 S1 RNA binding domain cNMP_binding PF00027.29 EAQ88144.1 - 3.6e-28 97.5 1.6 4.8e-17 61.8 0.0 5.8 6 0 0 6 6 6 3 Cyclic nucleotide-binding domain Patatin PF01734.22 EAQ88144.1 - 6.7e-15 55.8 0.5 2.7e-14 53.9 0.5 2.1 1 0 0 1 1 1 1 Patatin-like phospholipase TMEM43 PF07787.12 EAQ88144.1 - 0.87 8.9 4.3 1.5 8.2 4.3 1.3 1 0 0 1 1 1 0 Transmembrane protein 43 Pyridoxal_deC PF00282.19 EAQ88145.1 - 4e-99 331.9 0.0 6.2e-99 331.2 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Anoctamin PF04547.12 EAQ88146.1 - 1.1e-118 397.0 5.9 1.3e-118 396.7 5.9 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel DUF2970 PF11174.8 EAQ88146.1 - 0.01 15.7 0.1 0.1 12.5 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2970) Anoct_dimer PF16178.5 EAQ88146.1 - 0.073 12.8 0.0 2.3 7.9 0.0 2.3 1 1 0 2 2 2 0 Dimerisation domain of Ca+-activated chloride-channel, anoctamin DER1 PF04511.15 EAQ88146.1 - 0.82 9.6 8.5 0.065 13.2 3.2 1.9 2 0 0 2 2 2 0 Der1-like family FMN_dh PF01070.18 EAQ88148.1 - 4.8e-119 397.5 0.4 5.7e-119 397.2 0.4 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 EAQ88148.1 - 1.2e-23 83.0 0.0 2.4e-23 82.1 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 EAQ88148.1 - 1.5e-07 30.9 0.1 2.3e-07 30.3 0.1 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 EAQ88148.1 - 0.00011 21.3 2.0 0.00039 19.5 0.2 2.4 2 1 1 3 3 3 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 EAQ88148.1 - 0.00098 18.6 0.3 0.00098 18.6 0.3 1.4 2 0 0 2 2 2 1 Nitronate monooxygenase His_biosynth PF00977.21 EAQ88148.1 - 0.0041 16.6 0.8 0.2 11.1 0.1 2.3 1 1 0 2 2 2 1 Histidine biosynthesis protein T6SS_VasJ PF16989.5 EAQ88148.1 - 0.023 14.2 0.0 0.16 11.4 0.0 2.1 2 0 0 2 2 2 0 Type VI secretion, EvfE, EvfF, ImpA, BimE, VC_A0119, VasJ ThiG PF05690.14 EAQ88148.1 - 0.065 12.5 0.1 3 7.1 0.0 2.2 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG Ras PF00071.22 EAQ88149.1 - 9.7e-16 57.8 0.1 3.1e-13 49.7 0.2 2.1 2 0 0 2 2 2 2 Ras family Roc PF08477.13 EAQ88149.1 - 2.7e-14 53.4 0.1 4e-14 52.9 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase RTP1_C2 PF10304.9 EAQ88149.1 - 0.017 14.8 0.6 0.026 14.2 0.6 1.2 1 0 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 2 AAA_16 PF13191.6 EAQ88149.1 - 0.063 13.7 0.1 0.077 13.4 0.1 1.3 1 0 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.23 EAQ88149.1 - 0.081 13.0 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 50S ribosome-binding GTPase Arf PF00025.21 EAQ88149.1 - 0.087 12.3 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA_24 PF13479.6 EAQ88149.1 - 0.09 12.5 0.1 0.15 11.7 0.1 1.4 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EAQ88149.1 - 0.17 11.9 0.0 0.25 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DLIC PF05783.11 EAQ88149.1 - 0.24 10.2 0.0 0.35 9.6 0.0 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Borrelia_P83 PF05262.11 EAQ88150.1 - 3.3 6.1 33.3 4.6 5.6 33.3 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein SLATT_fungal PF18142.1 EAQ88151.1 - 1.9e-33 115.0 0.1 6.6e-33 113.2 0.0 1.9 2 0 0 2 2 2 1 SMODS and SLOG-associating 2TM effector domain Arabinose_bd PF12625.7 EAQ88151.1 - 0.0014 18.7 0.0 0.003 17.7 0.0 1.5 1 0 0 1 1 1 1 Arabinose-binding domain of AraC transcription regulator, N-term PilJ PF13675.6 EAQ88151.1 - 0.017 15.1 0.4 0.16 12.0 0.2 2.2 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Colicin PF01024.19 EAQ88151.1 - 0.052 13.4 0.5 0.052 13.4 0.5 1.9 2 0 0 2 2 2 0 Colicin pore forming domain DUF883 PF05957.13 EAQ88151.1 - 0.076 13.6 2.9 0.16 12.6 1.9 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) COG2 PF06148.11 EAQ88151.1 - 0.19 11.8 0.8 0.46 10.6 0.2 1.9 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 2OG-FeII_Oxy_3 PF13640.6 EAQ88152.1 - 1.1e-08 35.9 0.0 2.5e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MHYT PF03707.16 EAQ88153.1 - 0.032 14.4 1.4 0.11 12.7 1.4 2.0 1 0 0 1 1 1 0 Bacterial signalling protein N terminal repeat Pex14_N PF04695.13 EAQ88153.1 - 0.83 10.3 7.8 0.36 11.5 1.9 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region HTH_Tnp_Tc5 PF03221.16 EAQ88154.1 - 2.1e-19 69.3 0.6 2.8e-06 27.3 0.0 5.7 5 0 0 5 5 5 4 Tc5 transposase DNA-binding domain Homeobox_KN PF05920.11 EAQ88154.1 - 1e-13 50.9 0.2 1e-13 50.9 0.2 2.3 2 0 0 2 2 2 1 Homeobox KN domain Homeodomain PF00046.29 EAQ88154.1 - 7.6e-06 25.7 0.2 2.2e-05 24.2 0.2 1.8 1 0 0 1 1 1 1 Homeodomain zf-C2H2 PF00096.26 EAQ88154.1 - 0.0018 18.7 13.5 0.038 14.5 3.9 3.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EAQ88154.1 - 0.003 18.3 3.8 0.003 18.3 3.8 4.1 4 0 0 4 4 4 1 C2H2-type zinc finger Lsr2 PF11774.8 EAQ88154.1 - 0.11 12.6 1.7 16 5.7 0.0 3.2 2 0 0 2 2 2 0 Lsr2 TF_Zn_Ribbon PF08271.12 EAQ88154.1 - 0.62 9.6 5.5 27 4.4 2.3 3.3 3 1 0 3 3 3 0 TFIIB zinc-binding zf-H2C2_2 PF13465.6 EAQ88154.1 - 0.63 10.6 7.3 0.61 10.6 2.4 3.1 3 0 0 3 3 3 0 Zinc-finger double domain Mucin PF01456.17 EAQ88154.1 - 2.8 7.9 17.8 3.1 7.8 10.3 2.7 2 0 0 2 2 2 0 Mucin-like glycoprotein Elf1 PF05129.13 EAQ88154.1 - 3.1 7.9 6.2 3.3 7.8 4.3 2.1 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like Nipped-B_C PF12830.7 EAQ88155.1 - 6.6e-46 156.6 0.6 6.6e-46 156.6 0.6 3.6 4 1 0 4 4 4 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 EAQ88155.1 - 4.1e-07 30.2 0.5 4.1e-07 30.2 0.5 4.0 4 0 0 4 4 4 1 HEAT repeat associated with sister chromatid cohesion Cnd1 PF12717.7 EAQ88155.1 - 6.9e-07 29.4 0.3 5.4e-05 23.3 0.0 2.9 1 1 1 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EAQ88155.1 - 1.1e-06 28.4 1.6 0.41 11.0 0.0 5.2 4 0 0 4 4 4 2 HEAT repeat AT_hook PF02178.19 EAQ88155.1 - 0.24 11.4 5.0 1 9.5 5.0 2.2 1 0 0 1 1 1 0 AT hook motif TFIIS_C PF01096.18 EAQ88156.1 - 9.7e-12 44.5 3.6 9.7e-12 44.5 3.6 2.8 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 EAQ88156.1 - 4.2e-06 26.5 2.9 4.2e-06 26.5 2.9 2.7 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit C1_1 PF00130.22 EAQ88156.1 - 0.0083 16.0 7.5 0.02 14.7 1.3 2.7 2 1 1 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) HypA PF01155.19 EAQ88156.1 - 0.058 13.4 5.6 0.73 9.9 0.4 2.2 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA tRNA-synt_1f PF01921.18 EAQ88156.1 - 0.12 11.2 0.8 0.17 10.7 0.2 1.5 2 0 0 2 2 2 0 tRNA synthetases class I (K) zf-ribbon_3 PF13248.6 EAQ88156.1 - 0.3 10.6 10.4 1.1 8.8 0.4 3.7 3 0 0 3 3 3 0 zinc-ribbon domain Lar_restr_allev PF14354.6 EAQ88156.1 - 0.36 11.2 10.6 1.3 9.4 0.4 3.2 2 1 0 2 2 2 0 Restriction alleviation protein Lar zinc_ribbon_2 PF13240.6 EAQ88156.1 - 1.5 8.6 18.7 1.4 8.8 0.2 3.8 4 1 0 3 3 3 0 zinc-ribbon domain zf-ISL3 PF14690.6 EAQ88156.1 - 2.9 8.6 10.7 12 6.7 0.1 3.1 2 1 1 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Zn_ribbon_recom PF13408.6 EAQ88156.1 - 4.1 8.0 11.6 30 5.2 0.1 3.3 2 1 1 3 3 3 0 Recombinase zinc beta ribbon domain HEAT_2 PF13646.6 EAQ88157.1 - 8.2e-26 90.2 5.6 8.5e-13 48.5 0.4 3.7 2 2 2 4 4 4 2 HEAT repeats HEAT_PBS PF03130.16 EAQ88157.1 - 4.2e-19 67.2 7.0 0.0063 17.1 0.0 6.5 6 0 0 6 6 6 5 PBS lyase HEAT-like repeat HEAT_EZ PF13513.6 EAQ88157.1 - 8.7e-07 29.3 5.9 0.14 12.7 0.1 5.0 2 2 3 5 5 5 3 HEAT-like repeat HEAT PF02985.22 EAQ88157.1 - 1.1e-06 28.4 3.9 0.98 9.9 0.0 5.8 7 0 0 7 7 7 2 HEAT repeat AAA_lid_1 PF17857.1 EAQ88157.1 - 0.17 12.1 0.3 41 4.5 0.0 3.1 3 0 0 3 3 3 0 AAA+ lid domain RIFIN PF02009.16 EAQ88158.1 - 0.00051 20.1 0.1 0.00069 19.6 0.1 1.1 1 0 0 1 1 1 1 Rifin TMEM154 PF15102.6 EAQ88158.1 - 0.0014 18.6 4.6 0.0014 18.6 4.6 2.5 1 1 1 2 2 2 1 TMEM154 protein family DUF5305 PF17231.2 EAQ88158.1 - 0.0084 15.5 1.6 0.013 14.9 1.6 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5305) Orf78 PF06024.12 EAQ88158.1 - 0.0088 16.3 8.8 0.056 13.7 8.8 2.1 1 1 0 1 1 1 1 Orf78 (ac78) SAPS PF04499.15 EAQ88158.1 - 0.012 14.4 1.3 0.013 14.4 1.3 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SUR7 PF06687.12 EAQ88158.1 - 0.02 14.6 0.3 0.025 14.2 0.3 1.3 1 0 0 1 1 1 0 SUR7/PalI family DUF1180 PF06679.12 EAQ88158.1 - 0.02 15.3 20.9 0.024 15.1 18.6 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1180) LAP1C PF05609.12 EAQ88158.1 - 0.03 13.4 3.9 0.043 12.9 3.9 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) ECSCR PF15820.5 EAQ88158.1 - 0.051 13.4 0.3 0.19 11.6 0.3 1.9 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator SKG6 PF08693.10 EAQ88158.1 - 0.057 12.8 1.9 0.15 11.5 1.9 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain ABC2_membrane_3 PF12698.7 EAQ88158.1 - 0.078 12.1 1.6 0.11 11.6 1.6 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein TMEM132D_C PF15706.5 EAQ88158.1 - 0.13 12.1 1.5 0.4 10.5 1.5 1.8 1 1 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term DUF4064 PF13273.6 EAQ88158.1 - 0.15 12.4 0.3 0.31 11.3 0.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) SOG2 PF10428.9 EAQ88158.1 - 0.16 11.2 13.3 0.24 10.5 13.3 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein Peptidase_M56 PF05569.11 EAQ88158.1 - 0.21 10.7 0.1 0.3 10.3 0.1 1.2 1 0 0 1 1 1 0 BlaR1 peptidase M56 SPX PF03105.19 EAQ88158.1 - 0.32 10.9 11.4 0.42 10.5 11.4 1.1 1 0 0 1 1 1 0 SPX domain Tim54 PF11711.8 EAQ88158.1 - 0.33 9.7 1.2 0.44 9.3 1.2 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 NOA36 PF06524.12 EAQ88158.1 - 0.52 9.6 10.2 0.88 8.8 10.2 1.3 1 0 0 1 1 1 0 NOA36 protein OATP PF03137.20 EAQ88158.1 - 0.84 7.8 4.6 1.1 7.4 4.6 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Macoilin PF09726.9 EAQ88158.1 - 0.88 8.1 6.1 1.1 7.7 6.1 1.1 1 0 0 1 1 1 0 Macoilin family Podoplanin PF05808.11 EAQ88158.1 - 1.2 9.2 10.2 0.72 9.9 8.0 1.7 1 1 0 1 1 1 0 Podoplanin CPSF100_C PF13299.6 EAQ88158.1 - 4.7 7.4 6.2 7.4 6.7 6.2 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal RPN2_C PF18004.1 EAQ88158.1 - 5.5 6.9 9.3 8.4 6.3 9.3 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain GREB1 PF15782.5 EAQ88158.1 - 6.3 3.8 5.9 7.3 3.6 5.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Glyco_transf_90 PF05686.12 EAQ88159.1 - 6.9e-13 48.3 0.3 1.4e-05 24.2 0.0 4.0 3 2 0 3 3 3 3 Glycosyl transferase family 90 XPG_I_2 PF12813.7 EAQ88160.1 - 8.1e-79 264.6 0.0 1.2e-78 264.1 0.0 1.2 1 0 0 1 1 1 1 XPG domain containing Metallophos PF00149.28 EAQ88162.1 - 5.9e-12 46.5 0.7 9.2e-12 45.9 0.7 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EAQ88162.1 - 3.3e-06 27.4 0.1 1.7e-05 25.1 0.1 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Pribosyltran_N PF13793.6 EAQ88163.1 - 3.3e-42 143.1 0.0 4.7e-41 139.4 0.0 2.2 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 EAQ88163.1 - 5.5e-34 117.8 2.1 2.4e-29 102.7 0.1 3.2 3 1 0 3 3 3 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 EAQ88163.1 - 1.5e-08 34.3 0.0 0.0002 20.9 0.0 2.4 2 0 0 2 2 2 2 Phosphoribosyl transferase domain PAP_assoc PF03828.19 EAQ88164.1 - 7.2e-18 64.6 0.0 6.1e-12 45.6 0.0 2.7 2 0 0 2 2 2 2 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 EAQ88164.1 - 0.00034 20.8 0.0 0.00076 19.7 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 EAQ88164.1 - 0.063 13.4 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase TFIIF_alpha PF05793.12 EAQ88165.1 - 5.8 5.4 52.7 1.9e+02 0.4 50.8 2.6 1 1 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Bud13 PF09736.9 EAQ88166.1 - 8.7e-21 74.8 0.9 8.7e-21 74.8 0.9 2.1 3 0 0 3 3 3 1 Pre-mRNA-splicing factor of RES complex Zn_clus PF00172.18 EAQ88169.1 - 1.1e-06 28.7 10.3 1.8e-06 28.0 10.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RBR PF17208.3 EAQ88169.1 - 4.2 8.2 11.2 6.9 7.5 2.9 2.5 2 0 0 2 2 2 0 RNA binding Region SKI PF01202.22 EAQ88170.1 - 7e-21 75.0 0.0 1e-20 74.4 0.0 1.2 1 0 0 1 1 1 1 Shikimate kinase DHquinase_I PF01487.15 EAQ88170.1 - 2e-07 31.5 0.1 0.00091 19.5 0.0 3.0 3 1 1 4 4 4 2 Type I 3-dehydroquinase PAP_central PF04928.17 EAQ88171.1 - 5.3e-16 58.4 0.0 4.3e-15 55.4 0.0 2.2 2 0 0 2 2 2 1 Poly(A) polymerase central domain 2_5_RNA_ligase2 PF13563.6 EAQ88171.1 - 1.1e-14 54.6 0.6 1.4e-06 28.3 0.7 2.4 1 1 1 2 2 2 2 2'-5' RNA ligase superfamily Exo_endo_phos PF03372.23 EAQ88171.1 - 0.013 15.0 0.5 0.13 11.7 0.0 2.5 2 1 1 3 3 3 0 Endonuclease/Exonuclease/phosphatase family ResIII PF04851.15 EAQ88172.1 - 8.7e-25 87.7 0.0 4.1e-24 85.5 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EAQ88172.1 - 2e-14 53.9 0.0 1.4e-13 51.1 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 EAQ88172.1 - 4.4e-12 46.1 0.0 1.3e-11 44.6 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 EAQ88172.1 - 3.7e-05 23.5 0.0 8.1e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 SWI2/SNF2 ATPase DUF2075 PF09848.9 EAQ88172.1 - 0.0026 17.1 0.0 0.0053 16.0 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) DUF3072 PF11272.8 EAQ88172.1 - 0.0057 16.5 0.1 0.019 14.8 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3072) ERCC3_RAD25_C PF16203.5 EAQ88172.1 - 0.033 13.4 0.0 0.12 11.6 0.0 1.8 2 0 0 2 2 2 0 ERCC3/RAD25/XPB C-terminal helicase DUF1419 PF07215.11 EAQ88172.1 - 0.15 12.2 0.0 0.4 10.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1419) Stm1_N PF09598.10 EAQ88173.1 - 1 10.2 5.6 1.7 9.5 3.8 2.5 1 1 0 1 1 1 0 Stm1 PI3_PI4_kinase PF00454.27 EAQ88175.1 - 4e-43 148.0 0.0 5.6e-43 147.5 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TruB_C PF09142.11 EAQ88175.1 - 0.15 11.9 0.2 4.5 7.1 0.0 2.4 2 0 0 2 2 2 0 tRNA Pseudouridine synthase II, C terminal Methyltransf_23 PF13489.6 EAQ88176.1 - 0.00046 20.1 0.0 0.0064 16.3 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAQ88176.1 - 0.0053 17.4 0.0 3 8.6 0.0 2.7 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 EAQ88176.1 - 0.0068 17.0 0.0 0.38 11.4 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAQ88176.1 - 0.031 14.1 0.0 3.4 7.5 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_2 PF00891.18 EAQ88176.1 - 0.032 13.5 0.0 0.33 10.2 0.0 2.2 2 0 0 2 2 2 0 O-methyltransferase domain YqeY PF09424.10 EAQ88177.1 - 2.2e-18 66.7 4.9 2.7e-18 66.4 4.9 1.1 1 0 0 1 1 1 1 Yqey-like protein Lant_dehydr_C PF14028.6 EAQ88177.1 - 0.043 13.4 0.9 0.061 12.9 0.9 1.1 1 0 0 1 1 1 0 Lantibiotic biosynthesis dehydratase C-term SNF2_N PF00176.23 EAQ88178.1 - 9.6e-70 235.0 0.1 1.5e-69 234.3 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EAQ88178.1 - 3.7e-12 46.6 0.0 1.4e-11 44.7 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HIRAN PF08797.11 EAQ88178.1 - 3.2e-06 27.0 0.0 6.5e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 HIRAN domain DEAD PF00270.29 EAQ88178.1 - 1.4e-05 24.9 0.0 3.4e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_5 PF14634.6 EAQ88178.1 - 0.00068 19.6 3.4 0.0013 18.7 3.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain ResIII PF04851.15 EAQ88178.1 - 0.0018 18.3 0.0 0.007 16.4 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4_3 PF13920.6 EAQ88178.1 - 0.17 11.8 3.5 0.1 12.5 1.2 1.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EAQ88178.1 - 0.29 11.0 3.2 0.67 9.9 3.2 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DZR PF12773.7 EAQ88178.1 - 0.45 10.6 4.8 0.86 9.7 4.8 1.5 1 0 0 1 1 1 0 Double zinc ribbon zf-C3HC4_2 PF13923.6 EAQ88178.1 - 2.5 8.0 4.5 1.1 9.1 1.8 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FA_desaturase PF00487.24 EAQ88179.1 - 7.5e-18 65.3 11.9 7.5e-18 65.3 11.9 1.9 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.28 EAQ88179.1 - 9e-18 64.2 0.0 1.8e-17 63.2 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Pkinase_Tyr PF07714.17 EAQ88180.1 - 1.3e-11 44.3 0.0 2.3e-10 40.2 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EAQ88180.1 - 1.5e-11 44.1 0.0 1.2e-10 41.2 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Lon_C PF05362.13 EAQ88181.1 - 1.1e-64 217.8 0.0 2.2e-64 216.8 0.0 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 EAQ88181.1 - 7.7e-35 120.7 0.0 2.5e-34 119.0 0.0 1.9 2 0 0 2 2 2 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 EAQ88181.1 - 4e-10 40.2 0.5 9.9e-06 26.0 0.0 3.2 2 1 1 3 3 3 2 ATPase family associated with various cellular activities (AAA) ChlI PF13541.6 EAQ88181.1 - 1.1e-08 34.9 0.0 2.5e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_PrkA PF08298.11 EAQ88181.1 - 3.4e-05 22.9 0.0 7.3e-05 21.8 0.0 1.4 1 0 0 1 1 1 1 PrkA AAA domain RuvB_N PF05496.12 EAQ88181.1 - 5.5e-05 23.0 0.0 0.00073 19.3 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 EAQ88181.1 - 7e-05 22.8 0.0 0.00018 21.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EAQ88181.1 - 0.0014 19.0 0.5 0.0052 17.2 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 EAQ88181.1 - 0.0059 17.2 0.1 0.072 13.6 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 EAQ88181.1 - 0.021 15.1 0.0 0.067 13.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EAQ88181.1 - 0.043 13.7 0.0 0.13 12.1 0.0 1.8 1 0 0 1 1 1 0 RsgA GTPase RNA_helicase PF00910.22 EAQ88181.1 - 0.049 14.0 0.0 0.19 12.2 0.0 2.0 2 0 0 2 2 1 0 RNA helicase IstB_IS21 PF01695.17 EAQ88181.1 - 0.05 13.3 0.0 0.25 11.0 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_7 PF12775.7 EAQ88181.1 - 0.072 12.6 0.3 0.17 11.4 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region SKI PF01202.22 EAQ88181.1 - 0.084 13.0 0.0 0.4 10.8 0.0 2.1 2 0 0 2 2 2 0 Shikimate kinase F-box-like_2 PF13013.6 EAQ88181.1 - 0.11 12.4 0.0 0.32 11.0 0.0 1.7 1 0 0 1 1 1 0 F-box-like domain ABC_tran PF00005.27 EAQ88181.1 - 0.23 12.0 1.3 0.87 10.1 0.1 2.5 2 1 0 2 2 2 0 ABC transporter Med21 PF11221.8 EAQ88183.1 - 9.2e-23 81.1 0.3 9.4e-23 81.1 0.3 1.0 1 0 0 1 1 1 1 Subunit 21 of Mediator complex ATG16 PF08614.11 EAQ88183.1 - 0.048 13.9 0.3 0.051 13.8 0.3 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Hydrolase PF00702.26 EAQ88184.1 - 4.1e-13 50.1 0.0 4.8e-12 46.6 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EAQ88184.1 - 5e-13 49.5 0.0 7e-13 49.0 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Acid_PPase PF12689.7 EAQ88184.1 - 5.3e-05 23.1 0.1 0.00034 20.5 0.1 1.9 1 1 0 1 1 1 1 Acid Phosphatase Hydrolase_like PF13242.6 EAQ88184.1 - 0.00028 20.9 0.0 0.00045 20.2 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like KH_1 PF00013.29 EAQ88186.1 - 6.7e-31 105.9 0.4 1.3e-08 34.5 0.0 6.4 6 0 0 6 6 6 6 KH domain GCP_N_terminal PF17681.1 EAQ88187.1 - 2e-63 214.9 0.0 4.5e-63 213.7 0.0 1.6 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 EAQ88187.1 - 5.8e-58 196.8 10.8 5.8e-58 196.8 10.8 2.1 2 1 0 2 2 2 1 Gamma tubulin complex component C-terminal Proteasome PF00227.26 EAQ88188.1 - 7.4e-57 191.9 0.3 9.2e-57 191.6 0.3 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EAQ88188.1 - 1.1e-12 47.4 0.2 3.6e-12 45.7 0.0 2.0 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Fungal_trans_2 PF11951.8 EAQ88189.1 - 5e-13 48.6 2.3 1.2e-12 47.4 0.6 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Fungal_trans PF04082.18 EAQ88189.1 - 0.0016 17.5 0.5 0.0034 16.4 0.5 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Methyltransf_8 PF05148.15 EAQ88191.1 - 3.7e-56 190.4 0.0 8.7e-55 185.9 0.0 2.5 3 0 0 3 3 3 1 Hypothetical methyltransferase Methyltransf_11 PF08241.12 EAQ88191.1 - 4.1e-07 30.6 0.0 1.5e-06 28.7 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAQ88191.1 - 0.00013 22.6 0.3 0.00097 19.8 0.1 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAQ88191.1 - 0.0029 17.4 1.9 0.036 13.9 0.1 2.6 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 EAQ88191.1 - 0.038 13.5 0.0 1.2 8.6 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_32 PF13679.6 EAQ88191.1 - 0.38 10.7 0.0 0.38 10.7 0.0 3.4 3 1 0 3 3 3 0 Methyltransferase domain Asp_protease PF09668.10 EAQ88192.1 - 1.1e-58 196.4 0.2 1.6e-58 195.9 0.2 1.2 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 EAQ88192.1 - 1.5e-23 83.1 0.0 2.8e-23 82.3 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EAQ88192.1 - 1.6e-11 44.6 0.0 3.2e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease ubiquitin PF00240.23 EAQ88192.1 - 1e-08 34.8 0.0 2e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 EAQ88192.1 - 5.8e-08 32.5 0.0 1.2e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain UBA_4 PF14555.6 EAQ88192.1 - 2.1e-05 24.3 0.1 4.6e-05 23.2 0.1 1.6 1 0 0 1 1 1 1 UBA-like domain RVP_2 PF08284.11 EAQ88192.1 - 0.00021 21.1 0.0 0.0004 20.2 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.20 EAQ88192.1 - 0.00039 20.7 0.0 0.0009 19.5 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Rad60-SLD PF11976.8 EAQ88192.1 - 0.0084 15.9 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like YukD PF08817.10 EAQ88192.1 - 0.027 15.2 0.2 0.11 13.2 0.0 2.2 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein YukD Ubiquitin_2 PF14560.6 EAQ88192.1 - 0.046 14.2 0.0 0.093 13.2 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-like domain UN_NPL4 PF11543.8 EAQ88192.1 - 0.071 13.6 0.0 0.16 12.5 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Acetyltransf_1 PF00583.25 EAQ88193.1 - 1.7e-05 25.0 0.0 2.4e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EAQ88193.1 - 0.021 15.3 0.0 0.031 14.7 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Pribosyltran PF00156.27 EAQ88194.1 - 8.5e-16 57.9 0.2 1.3e-15 57.3 0.2 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain NOG1_N PF17835.1 EAQ88195.1 - 3e-44 150.8 0.4 8.3e-44 149.4 0.4 1.8 1 0 0 1 1 1 1 NOG1 N-terminal helical domain NOGCT PF08155.11 EAQ88195.1 - 1e-26 92.7 0.8 2.5e-26 91.4 0.8 1.7 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.14 EAQ88195.1 - 2.6e-26 91.1 0.2 5e-26 90.2 0.2 1.5 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.23 EAQ88195.1 - 7.5e-11 42.1 0.0 1.6e-10 41.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EAQ88195.1 - 7.5e-06 25.6 0.0 1.3e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.6 EAQ88195.1 - 0.015 15.7 0.1 0.16 12.3 0.0 2.7 3 0 0 3 3 3 0 AAA ATPase domain Gtr1_RagA PF04670.12 EAQ88195.1 - 0.047 13.0 0.1 0.09 12.1 0.1 1.4 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EAQ88195.1 - 0.052 13.5 0.1 3.2 7.6 0.1 3.1 3 0 0 3 3 3 0 RsgA GTPase GDI PF00996.18 EAQ88196.1 - 8e-188 624.3 0.0 9.9e-188 624.1 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.6 EAQ88196.1 - 0.053 13.8 0.0 0.23 11.7 0.0 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain MRP-L47 PF06984.13 EAQ88197.1 - 1.6e-23 82.6 1.4 2.8e-23 81.8 1.4 1.4 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Fungal_trans PF04082.18 EAQ88199.1 - 7.3e-17 61.3 0.1 1.2e-16 60.6 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.6 EAQ88199.1 - 3.1e-06 27.3 8.7 3.3e-05 24.1 2.2 2.6 2 0 0 2 2 2 2 Zinc-finger double domain zf-Di19 PF05605.12 EAQ88199.1 - 0.0014 18.9 5.5 0.0031 17.8 5.5 1.6 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 EAQ88199.1 - 0.0023 18.6 15.8 0.059 14.2 5.9 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 EAQ88199.1 - 0.17 12.4 14.9 0.35 11.4 7.3 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 EAQ88199.1 - 0.72 10.2 4.2 8.3 6.8 0.8 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding GCP_C_terminal PF04130.13 EAQ88201.1 - 9.8e-66 222.3 0.0 1.5e-65 221.7 0.0 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 EAQ88201.1 - 4.2e-25 89.0 0.0 7.9e-25 88.1 0.0 1.4 1 1 0 1 1 1 1 Gamma tubulin complex component N-terminal Robl_LC7 PF03259.17 EAQ88201.1 - 0.055 13.2 0.0 2.2 8.1 0.1 2.6 2 0 0 2 2 2 0 Roadblock/LC7 domain Trypan_PARP PF05887.11 EAQ88201.1 - 0.058 13.4 2.6 0.17 11.9 2.6 1.7 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DASH_Ask1 PF08655.10 EAQ88202.1 - 8.4e-22 76.8 0.1 1.4e-21 76.1 0.1 1.3 1 0 0 1 1 1 1 DASH complex subunit Ask1 Eaf7 PF07904.13 EAQ88202.1 - 5.2e-16 58.9 1.5 3.6e-15 56.3 0.0 2.8 2 1 0 2 2 2 1 Chromatin modification-related protein EAF7 GRP PF07172.11 EAQ88202.1 - 0.4 11.4 5.8 1.4 9.6 5.8 1.9 1 0 0 1 1 1 0 Glycine rich protein family Ribonuc_red_lgN PF00317.21 EAQ88204.1 - 0.26 11.3 1.3 15 5.7 1.4 2.9 2 1 0 2 2 2 0 Ribonucleotide reductase, all-alpha domain AAA_33 PF13671.6 EAQ88205.1 - 5.8e-15 55.7 0.0 1.2e-14 54.7 0.0 1.5 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 EAQ88205.1 - 2.9e-08 33.2 0.0 5.6e-08 32.3 0.0 1.4 1 1 0 1 1 1 1 Zeta toxin CoaE PF01121.20 EAQ88205.1 - 3.8e-05 23.4 0.0 6.2e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Dephospho-CoA kinase KTI12 PF08433.10 EAQ88205.1 - 0.00012 21.7 0.0 0.00015 21.3 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_18 PF13238.6 EAQ88205.1 - 0.00016 22.2 0.1 0.00073 20.1 0.0 2.1 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 EAQ88205.1 - 0.0015 19.0 0.2 0.0047 17.3 0.2 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.6 EAQ88205.1 - 0.0027 18.0 0.0 0.0056 16.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain Ploopntkinase3 PF18751.1 EAQ88205.1 - 0.0034 17.3 0.0 0.023 14.6 0.0 2.0 2 0 0 2 2 2 1 P-loop Nucleotide Kinase3 AAA_29 PF13555.6 EAQ88205.1 - 0.0062 16.3 0.1 0.39 10.5 0.0 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain NB-ARC PF00931.22 EAQ88205.1 - 0.0068 15.6 0.1 0.022 13.9 0.0 1.8 2 1 0 2 2 2 1 NB-ARC domain AAA_17 PF13207.6 EAQ88205.1 - 0.007 16.8 0.0 0.031 14.7 0.0 2.1 3 0 0 3 3 2 1 AAA domain APS_kinase PF01583.20 EAQ88205.1 - 0.011 15.6 0.0 0.016 15.1 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase dNK PF01712.19 EAQ88205.1 - 0.022 14.6 0.0 0.033 14.0 0.0 1.3 1 0 0 1 1 1 0 Deoxynucleoside kinase MeaB PF03308.16 EAQ88205.1 - 0.029 13.4 0.0 0.061 12.3 0.0 1.5 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Mg_chelatase PF01078.21 EAQ88205.1 - 0.043 13.2 0.0 0.081 12.3 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 EAQ88205.1 - 0.048 14.1 0.0 0.078 13.4 0.0 1.5 1 1 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 EAQ88205.1 - 0.068 12.9 0.0 0.13 12.0 0.0 1.5 2 0 0 2 2 2 0 AAA domain 6PF2K PF01591.18 EAQ88205.1 - 0.068 12.5 0.0 12 5.1 0.0 2.3 2 0 0 2 2 2 0 6-phosphofructo-2-kinase Cytidylate_kin2 PF13189.6 EAQ88205.1 - 0.09 12.9 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Cytidylate kinase-like family RsgA_GTPase PF03193.16 EAQ88205.1 - 0.1 12.5 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_22 PF13401.6 EAQ88205.1 - 0.1 12.9 0.0 0.34 11.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAQ88205.1 - 0.11 12.1 0.2 1.5 8.3 0.0 2.3 2 1 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 EAQ88205.1 - 0.11 12.5 0.0 0.39 10.8 0.0 1.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF1487 PF07368.11 EAQ88205.1 - 0.12 11.8 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1487) Viral_helicase1 PF01443.18 EAQ88205.1 - 0.13 12.0 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase PRK PF00485.18 EAQ88205.1 - 0.14 11.9 0.0 0.22 11.2 0.0 1.4 1 1 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family p450 PF00067.22 EAQ88206.1 - 5.8e-54 183.6 0.0 7.8e-54 183.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Yip1 PF04893.17 EAQ88207.1 - 3.3e-13 49.7 16.2 6.1e-13 48.8 16.2 1.5 1 1 0 1 1 1 1 Yip1 domain DUF2070 PF09843.9 EAQ88207.1 - 0.067 11.5 4.4 0.088 11.1 4.4 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Ribosomal_L40e PF01020.17 EAQ88208.1 - 1.2e-31 108.4 10.4 1.4e-31 108.1 10.4 1.1 1 0 0 1 1 1 1 Ribosomal L40e family EFP_N PF08207.12 EAQ88210.1 - 0.01 15.8 0.0 0.019 15.0 0.0 1.4 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain eIF-5a PF01287.20 EAQ88210.1 - 0.13 12.4 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold Vps52 PF04129.12 EAQ88211.1 - 2.1e-100 336.9 0.1 3.4e-73 247.1 0.0 2.0 1 1 1 2 2 2 2 Vps52 / Sac2 family Sec3_C PF09763.9 EAQ88211.1 - 8.1e-05 21.2 0.1 0.0002 19.9 0.0 1.6 1 1 1 2 2 2 1 Exocyst complex component Sec3 COG2 PF06148.11 EAQ88211.1 - 0.0078 16.3 0.3 0.029 14.5 0.1 2.0 3 0 0 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 Mer2 PF09074.10 EAQ88211.1 - 0.023 14.5 0.0 0.045 13.6 0.0 1.5 1 0 0 1 1 1 0 Mer2 Filament PF00038.21 EAQ88211.1 - 0.14 11.7 0.1 0.3 10.6 0.1 1.5 1 0 0 1 1 1 0 Intermediate filament protein QWRF PF04484.12 EAQ88211.1 - 0.69 9.6 0.0 0.69 9.6 0.0 2.2 2 0 0 2 2 2 0 QWRF family RabGAP-TBC PF00566.18 EAQ88212.1 - 1.7e-18 67.1 0.0 2.1e-18 66.7 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain MMS1_N PF10433.9 EAQ88213.1 - 9.8e-41 139.9 0.0 1.9e-40 138.9 0.0 1.5 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term GTP_EFTU PF00009.27 EAQ88214.1 - 8.7e-35 120.0 0.0 8.7e-35 120.0 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 EAQ88214.1 - 8.4e-20 70.9 0.0 2.5e-19 69.3 0.0 1.9 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D4 PF14578.6 EAQ88214.1 - 4.5e-09 36.1 0.2 2.3e-08 33.8 0.2 2.3 1 0 0 1 1 1 1 Elongation factor Tu domain 4 GTP_EFTU_D2 PF03144.25 EAQ88214.1 - 1.9e-08 34.5 11.1 2.2e-07 31.1 0.1 3.7 4 0 0 4 4 4 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EAQ88214.1 - 4.7e-07 29.9 3.3 2.8e-06 27.4 0.0 3.6 3 0 0 3 3 3 1 50S ribosome-binding GTPase Roc PF08477.13 EAQ88214.1 - 0.0001 22.5 0.0 0.00038 20.7 0.0 2.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 EAQ88214.1 - 0.0014 18.5 0.0 0.0014 18.5 0.0 2.1 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 EAQ88214.1 - 0.013 15.4 1.0 0.28 11.1 0.2 3.2 2 1 1 3 3 3 0 RsgA GTPase Ras PF00071.22 EAQ88214.1 - 0.022 14.3 0.0 0.14 11.7 0.0 2.5 1 1 0 1 1 1 0 Ras family HSP70 PF00012.20 EAQ88215.1 - 2.9e-159 531.1 14.5 2.9e-159 531.1 14.5 2.2 2 1 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 EAQ88215.1 - 7.9e-11 41.3 0.0 7e-10 38.2 0.0 2.2 2 0 0 2 2 2 1 MreB/Mbl protein BcrAD_BadFG PF01869.20 EAQ88215.1 - 0.017 14.6 0.0 0.075 12.5 0.0 2.1 1 1 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family Chitin_synth_2 PF03142.15 EAQ88216.1 - 2.1e-14 53.1 0.3 3.6e-14 52.3 0.3 1.3 1 1 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.6 EAQ88216.1 - 1.2e-11 44.9 2.2 2.4e-11 44.0 2.2 1.4 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EAQ88216.1 - 2.4e-06 27.6 1.3 5.3e-05 23.2 0.6 2.0 1 1 1 2 2 2 2 Glycosyltransferase like family 2 MIF4G PF02854.19 EAQ88218.1 - 1.3e-57 194.8 0.0 3.4e-31 108.6 0.0 3.8 4 1 0 4 4 4 2 MIF4G domain Upf2 PF04050.14 EAQ88218.1 - 7.4e-39 133.6 3.4 7.4e-39 133.6 3.4 2.0 2 0 0 2 2 2 1 Up-frameshift suppressor 2 Mo-co_dimer PF03404.16 EAQ88219.1 - 1.5e-57 193.5 0.0 2.4e-57 192.8 0.0 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Oxidored_molyb PF00174.19 EAQ88219.1 - 3.6e-57 192.7 0.0 5.5e-57 192.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain FAD_binding_6 PF00970.24 EAQ88219.1 - 2.3e-32 111.3 0.0 5.7e-32 110.0 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain HTH_32 PF13565.6 EAQ88220.1 - 1.6e-06 28.6 1.6 2.7e-06 27.9 0.8 1.7 1 1 1 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 EAQ88220.1 - 9.3e-05 22.5 0.1 0.00017 21.6 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 EAQ88220.1 - 0.00041 20.1 0.3 0.0015 18.3 0.0 1.9 2 0 0 2 2 2 1 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 EAQ88220.1 - 0.029 14.6 0.3 0.056 13.7 0.1 1.6 2 0 0 2 2 2 0 Transposase HTH_Tnp_ISL3 PF13542.6 EAQ88220.1 - 0.031 13.7 0.6 0.23 10.9 0.1 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 HTH_WhiA PF02650.14 EAQ88220.1 - 0.13 12.6 0.1 0.26 11.6 0.1 1.6 1 1 0 1 1 1 0 WhiA C-terminal HTH domain ETC_C1_NDUFA5 PF04716.14 EAQ88221.1 - 8.9e-26 89.5 0.4 7.5e-24 83.3 0.0 2.5 2 0 0 2 2 2 2 ETC complex I subunit conserved region PAS_3 PF08447.12 EAQ88223.1 - 1.3e-15 57.4 0.0 1e-09 38.5 0.0 2.3 2 0 0 2 2 2 2 PAS fold PAS PF00989.25 EAQ88223.1 - 4e-09 36.5 0.0 0.00079 19.4 0.0 2.7 3 0 0 3 3 3 2 PAS fold PAS_9 PF13426.7 EAQ88223.1 - 6.9e-08 32.7 0.0 0.002 18.4 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.10 EAQ88223.1 - 2.1e-05 24.7 0.0 0.067 13.4 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS_8 PF13188.7 EAQ88223.1 - 0.023 14.7 0.0 1.4 9.0 0.0 2.8 3 0 0 3 3 3 0 PAS domain PAS_11 PF14598.6 EAQ88223.1 - 0.028 14.5 0.0 0.16 12.1 0.0 1.9 2 0 0 2 2 2 0 PAS domain PAS_12 PF18095.1 EAQ88223.1 - 0.096 12.3 0.0 7.3 6.2 0.0 2.2 2 0 0 2 2 2 0 UPF0242 C-terminal PAS-like domain Na_Ca_ex PF01699.24 EAQ88225.1 - 2.9e-25 89.0 21.5 7.6e-14 51.9 7.8 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF1298 PF06974.13 EAQ88225.1 - 0.0009 19.2 0.0 0.0025 17.8 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1298) DUF2391 PF09622.10 EAQ88225.1 - 0.0082 15.5 4.3 0.018 14.4 4.3 1.7 1 1 0 1 1 1 1 Putative integral membrane protein (DUF2391) 7tm_7 PF08395.12 EAQ88225.1 - 0.0092 15.2 1.6 0.036 13.3 0.1 2.1 1 1 1 2 2 2 1 7tm Chemosensory receptor Claudin_2 PF13903.6 EAQ88225.1 - 0.053 13.3 1.4 1.9 8.2 0.2 2.5 1 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DEAD PF00270.29 EAQ88226.1 - 1.2e-17 64.2 0.0 3e-17 62.9 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EAQ88226.1 - 5e-12 46.1 0.0 1.3e-11 44.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1998 PF09369.10 EAQ88226.1 - 3.4e-11 43.8 0.0 9.9e-11 42.3 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) ResIII PF04851.15 EAQ88226.1 - 0.0043 17.1 0.0 0.013 15.5 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Ran_BP1 PF00638.18 EAQ88227.1 - 1e-06 29.0 1.1 0.00022 21.5 0.1 2.4 2 0 0 2 2 2 2 RanBP1 domain zf-RING_2 PF13639.6 EAQ88229.1 - 4.4e-14 52.5 17.5 2.6e-13 50.1 6.6 2.3 2 0 0 2 2 2 2 Ring finger domain zf-RING_11 PF17123.5 EAQ88229.1 - 1.8e-11 43.6 1.9 1.8e-11 43.6 1.9 2.3 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 EAQ88229.1 - 1.7e-09 37.3 5.8 1.7e-09 37.3 5.8 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EAQ88229.1 - 1.4e-08 34.4 11.3 3.7e-07 29.9 3.5 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EAQ88229.1 - 7e-07 29.0 16.6 1e-05 25.3 6.0 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EAQ88229.1 - 1.5e-06 28.4 5.2 1.5e-06 28.4 5.2 2.4 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 EAQ88229.1 - 1.7e-05 24.7 11.3 3.6e-05 23.6 3.4 2.3 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EAQ88229.1 - 9.7e-05 22.2 13.7 0.0033 17.3 5.4 2.3 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zinc_ribbon_9 PF14369.6 EAQ88229.1 - 0.00012 22.3 5.5 0.00016 21.9 2.5 2.4 2 0 0 2 2 2 1 zinc-ribbon zf-RING_UBOX PF13445.6 EAQ88229.1 - 0.0025 17.8 1.4 0.0025 17.8 1.4 3.3 2 1 1 3 3 3 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 EAQ88229.1 - 0.018 15.1 2.1 0.018 15.1 2.1 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_1 PF14446.6 EAQ88229.1 - 0.046 13.7 8.2 0.25 11.3 1.4 3.1 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 HypA PF01155.19 EAQ88229.1 - 0.058 13.4 0.4 0.058 13.4 0.4 2.2 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA PHD PF00628.29 EAQ88229.1 - 0.26 11.2 13.7 1 9.3 5.6 2.4 2 0 0 2 2 2 0 PHD-finger zinc-ribbons_6 PF07191.12 EAQ88229.1 - 0.83 9.7 7.0 0.63 10.1 0.3 2.4 2 0 0 2 2 2 0 zinc-ribbons zf-RING_4 PF14570.6 EAQ88229.1 - 0.99 9.3 12.5 1.6 8.6 3.7 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain DZR PF12773.7 EAQ88229.1 - 4.2 7.5 6.6 1.4 9.0 0.5 2.4 2 0 0 2 2 2 0 Double zinc ribbon Zn_ribbon_17 PF17120.5 EAQ88229.1 - 5.7 6.7 13.6 0.49 10.0 5.5 2.2 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type Fis1_TPR_C PF14853.6 EAQ88230.1 - 1.5e-24 85.8 0.7 2e-24 85.4 0.7 1.2 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 EAQ88230.1 - 1e-10 41.0 0.0 1.7e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.17 EAQ88230.1 - 0.0024 17.8 0.3 0.0045 17.0 0.3 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat Spc24 PF08286.11 EAQ88231.1 - 6.6e-37 126.0 0.1 1.8e-35 121.3 0.0 2.2 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 DUF1633 PF07794.11 EAQ88231.1 - 0.054 11.7 0.1 0.08 11.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1633) CLZ PF16526.5 EAQ88231.1 - 0.16 12.3 7.9 3.9 7.9 0.5 2.5 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Miff PF05644.11 EAQ88231.1 - 0.4 10.3 3.1 0.62 9.6 3.1 1.2 1 0 0 1 1 1 0 Mitochondrial and peroxisomal fission factor Mff APG6_N PF17675.1 EAQ88231.1 - 0.43 11.1 10.0 0.73 10.4 10.0 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region ATG16 PF08614.11 EAQ88231.1 - 1.3 9.2 12.3 4.7 7.4 10.7 2.1 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) JAKMIP_CC3 PF16034.5 EAQ88231.1 - 1.4 8.8 6.5 3.2 7.6 6.5 1.5 1 1 0 1 1 1 0 JAKMIP CC3 domain SlyX PF04102.12 EAQ88231.1 - 3.1 8.5 5.6 5 7.8 1.5 2.8 1 1 1 2 2 2 0 SlyX Prefoldin_2 PF01920.20 EAQ88231.1 - 3.1 7.8 5.3 3 7.8 1.0 2.1 2 0 0 2 2 2 0 Prefoldin subunit Ribosomal_L29 PF00831.23 EAQ88231.1 - 4.3 7.4 6.0 9.2 6.3 0.4 2.4 2 0 0 2 2 2 0 Ribosomal L29 protein Trimer_CC PF08954.11 EAQ88231.1 - 4.7 6.8 7.3 20 4.8 1.9 2.8 2 1 1 3 3 3 0 Trimerisation motif TatD_DNase PF01026.21 EAQ88232.1 - 5.3e-30 104.6 0.0 1.6e-29 103.1 0.0 1.7 1 1 0 1 1 1 1 TatD related DNase Fungal_trans PF04082.18 EAQ88233.1 - 8.6e-12 44.6 0.1 3e-08 33.0 0.0 2.3 1 1 1 2 2 2 2 Fungal specific transcription factor domain Methyltr_RsmB-F PF01189.17 EAQ88234.1 - 1.1e-31 110.1 0.0 6.2e-25 88.0 0.0 3.0 3 0 0 3 3 3 2 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 EAQ88234.1 - 0.029 14.5 0.0 0.073 13.2 0.0 1.7 1 1 0 1 1 1 0 FtsJ-like methyltransferase GTP1_OBG PF01018.22 EAQ88235.1 - 5.5e-38 130.0 2.8 4.4e-28 97.8 5.0 2.3 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.23 EAQ88235.1 - 7.7e-23 80.8 0.0 1.4e-22 79.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EAQ88235.1 - 1.8e-07 30.8 0.3 5.3e-07 29.3 0.1 1.9 3 0 0 3 3 3 1 Ferrous iron transport protein B ABC_tran PF00005.27 EAQ88235.1 - 0.049 14.2 0.0 0.09 13.3 0.0 1.4 1 0 0 1 1 1 0 ABC transporter MeaB PF03308.16 EAQ88235.1 - 0.073 12.0 0.1 1.7 7.6 0.0 2.6 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Arf PF00025.21 EAQ88235.1 - 0.099 12.1 0.0 0.45 9.9 0.0 1.9 2 0 0 2 2 2 0 ADP-ribosylation factor family APH PF01636.23 EAQ88237.1 - 1.1e-11 45.2 0.3 2.4e-11 44.0 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EAQ88237.1 - 4.1e-06 26.6 0.0 6.4e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.11 EAQ88237.1 - 0.036 12.9 0.0 1.5 7.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) Pkinase PF00069.25 EAQ88237.1 - 0.053 12.9 0.0 0.077 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain ABC_tran_CTD PF16326.5 EAQ88238.1 - 0.00096 19.4 1.7 0.00096 19.4 1.7 6.5 4 1 4 8 8 8 2 ABC transporter C-terminal domain DUF4407 PF14362.6 EAQ88238.1 - 0.0041 16.5 48.6 0.64 9.3 18.5 3.4 2 1 1 3 3 3 3 Domain of unknown function (DUF4407) Occludin_ELL PF07303.13 EAQ88238.1 - 0.16 12.7 25.5 0.05 14.3 2.5 4.8 4 1 1 5 5 5 0 Occludin homology domain DASH_Duo1 PF08651.10 EAQ88238.1 - 0.4 10.5 3.2 1 9.2 0.2 3.2 2 2 2 4 4 4 0 DASH complex subunit Duo1 CorA PF01544.18 EAQ88238.1 - 1.6 7.9 10.3 0.15 11.3 5.2 2.0 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein DUF4363 PF14276.6 EAQ88238.1 - 4.1 7.5 15.1 0.12 12.5 4.3 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4363) CotJB PF12652.7 EAQ88238.1 - 5.9 7.2 6.0 2.4 8.5 0.1 3.2 3 1 1 4 4 4 0 CotJB protein Golgin_A5 PF09787.9 EAQ88238.1 - 6.6 6.1 38.9 0.26 10.7 15.0 3.1 2 1 1 3 3 3 0 Golgin subfamily A member 5 RNA_pol_Rpb5_C PF01191.19 EAQ88239.1 - 1.2e-33 114.8 0.2 2e-33 114.1 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 EAQ88239.1 - 5.7e-14 52.5 0.0 9.8e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.12 EAQ88239.1 - 0.03 14.3 0.0 0.071 13.1 0.0 1.6 1 0 0 1 1 1 0 Restriction endonuclease AAA_3 PF07726.11 EAQ88239.1 - 0.15 11.9 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SH3_2 PF07653.17 EAQ88239.1 - 0.18 11.5 0.0 0.33 10.7 0.0 1.4 1 0 0 1 1 1 0 Variant SH3 domain C166 PF17615.2 EAQ88242.1 - 1.9e-21 76.9 5.0 3.9e-21 75.8 5.0 1.5 1 1 0 1 1 1 1 Family of unknown function Zip PF02535.22 EAQ88243.1 - 1.8e-52 178.7 8.5 9.8e-51 172.9 8.5 2.2 1 1 0 1 1 1 1 ZIP Zinc transporter Bul1_C PF04426.12 EAQ88244.1 - 1.9e-08 34.1 0.0 3.3e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Bul1 C terminus Bul1_N PF04425.12 EAQ88244.1 - 0.00025 19.9 1.0 0.00082 18.2 0.0 2.3 3 1 0 3 3 3 1 Bul1 N terminus zf-RVT PF13966.6 EAQ88245.1 - 0.08 13.7 0.0 0.22 12.2 0.0 1.7 2 0 0 2 2 2 0 zinc-binding in reverse transcriptase Metallophos PF00149.28 EAQ88246.1 - 5.1e-08 33.7 4.4 9.5e-08 32.8 4.4 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EAQ88246.1 - 7.4e-05 23.0 0.1 0.00036 20.8 0.1 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain MCM3AP_GANP PF16769.5 EAQ88246.1 - 0.65 8.2 1.3 0.93 7.7 1.3 1.1 1 0 0 1 1 1 0 MCM3AP domain of GANP Pex2_Pex12 PF04757.14 EAQ88247.1 - 1.8e-54 184.8 1.8 2.6e-54 184.2 1.8 1.3 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_2 PF13639.6 EAQ88247.1 - 0.016 15.5 4.2 0.026 14.9 4.2 1.3 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_4 PF15227.6 EAQ88247.1 - 0.037 14.2 1.4 0.061 13.5 1.4 1.3 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 EAQ88247.1 - 0.059 13.2 2.1 0.095 12.6 2.1 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EAQ88247.1 - 0.092 12.6 4.0 0.17 11.8 4.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) F-box PF00646.33 EAQ88248.1 - 2.3e-08 33.7 0.1 1.8e-07 30.8 0.0 2.3 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 EAQ88248.1 - 3.7e-07 29.9 0.2 8e-07 28.9 0.2 1.6 1 0 0 1 1 1 1 F-box-like Fungal_trans PF04082.18 EAQ88249.1 - 1.3e-66 224.3 0.1 1.8e-66 223.9 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 EAQ88249.1 - 0.079 13.5 0.1 0.24 11.9 0.1 1.9 1 0 0 1 1 1 0 Zinc finger, C2H2 type SAP30_Sin3_bdg PF13867.6 EAQ88251.1 - 2e-08 34.4 2.4 3.8e-08 33.5 0.3 2.1 2 0 0 2 2 2 1 Sin3 binding region of histone deacetylase complex subunit SAP30 CtnDOT_TraJ PF07863.11 EAQ88251.1 - 1.2 9.9 3.2 2.3 8.9 3.2 1.5 1 0 0 1 1 1 0 Homologues of TraJ from Bacteroides conjugative transposon DnaJ_C PF01556.18 EAQ88252.1 - 5.8e-36 123.8 0.0 8.2e-36 123.3 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EAQ88252.1 - 2.5e-23 82.0 0.8 4.9e-23 81.0 0.8 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EAQ88252.1 - 1.4e-09 38.2 20.5 2.8e-09 37.2 20.5 1.6 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 EAQ88252.1 - 6 6.9 23.2 0.62 10.1 4.1 3.1 2 1 1 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 EAQ88252.1 - 9 6.4 9.9 36 4.4 1.0 2.4 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA MFS_1 PF07690.16 EAQ88253.1 - 7.7e-39 133.6 44.0 7.9e-38 130.3 42.8 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EAQ88253.1 - 4.7e-09 35.2 18.3 1.1e-08 34.0 18.4 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Fungal_trans PF04082.18 EAQ88254.1 - 1.6e-19 70.0 0.0 2.5e-19 69.4 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EAQ88254.1 - 1.5e-08 34.6 11.3 2.6e-08 33.8 11.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ferric_reduct PF01794.19 EAQ88255.1 - 1.1e-17 64.4 17.4 1.1e-17 64.4 17.4 2.6 3 0 0 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 EAQ88255.1 - 7.7e-06 26.0 0.0 1.8e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain Ctr PF04145.15 EAQ88256.1 - 1.5e-11 45.2 0.0 1.5e-11 45.2 0.0 1.2 1 0 0 1 1 1 1 Ctr copper transporter family ABC2_membrane PF01061.24 EAQ88256.1 - 0.019 14.4 2.9 0.026 14.0 2.9 1.1 1 0 0 1 1 1 0 ABC-2 type transporter Ferric_reduct PF01794.19 EAQ88257.1 - 5.8e-22 78.1 10.0 5.8e-22 78.1 10.0 2.0 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 EAQ88257.1 - 0.0025 17.9 0.0 1.5 8.9 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EAQ88257.1 - 0.0079 16.3 0.0 0.014 15.4 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 EAQ88257.1 - 0.014 16.0 0.1 3.6 8.3 0.0 2.4 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain SUIM_assoc PF16619.5 EAQ88257.1 - 0.058 13.5 1.8 0.12 12.5 1.8 1.4 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 DUF420 PF04238.12 EAQ88257.1 - 0.16 12.3 8.1 0.44 10.8 7.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF420) zf-RING_2 PF13639.6 EAQ88258.1 - 2.9e-11 43.5 3.1 4.1e-11 43.0 3.1 1.2 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EAQ88258.1 - 3e-09 36.6 0.8 4e-09 36.2 0.8 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EAQ88258.1 - 6.6e-09 35.5 1.8 9e-09 35.0 1.8 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EAQ88258.1 - 7.7e-09 35.7 2.1 1.2e-08 35.1 2.1 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 EAQ88258.1 - 1.1e-06 28.2 1.8 2e-06 27.5 1.8 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_5 PF14634.6 EAQ88258.1 - 8.3e-06 25.7 1.1 1.2e-05 25.2 1.1 1.2 1 0 0 1 1 1 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 EAQ88258.1 - 2.2e-05 24.0 0.6 4e-05 23.1 0.6 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 EAQ88258.1 - 5.2e-05 23.2 0.5 7.6e-05 22.7 0.5 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 EAQ88258.1 - 5.2e-05 23.2 2.0 0.00019 21.4 2.3 1.7 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EAQ88258.1 - 0.0001 22.1 0.7 0.00015 21.5 0.7 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EAQ88258.1 - 0.00094 19.0 2.4 0.0016 18.3 2.4 1.4 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 RINGv PF12906.7 EAQ88258.1 - 0.0032 17.6 0.9 0.0053 16.8 0.9 1.3 1 0 0 1 1 1 1 RING-variant domain zf-RING-like PF08746.11 EAQ88258.1 - 0.0043 17.3 0.8 0.0058 16.9 0.8 1.3 1 0 0 1 1 1 1 RING-like domain FANCL_C PF11793.8 EAQ88258.1 - 0.013 15.6 3.2 0.11 12.7 3.2 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain zinc_ribbon_16 PF17034.5 EAQ88258.1 - 0.029 14.6 0.4 0.043 14.0 0.4 1.3 1 0 0 1 1 1 0 Zinc-ribbon like family zf-C3HC4_4 PF15227.6 EAQ88258.1 - 0.029 14.5 1.9 0.049 13.8 1.9 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 EAQ88258.1 - 0.13 12.1 0.9 0.19 11.5 0.9 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3H2C3 PF17122.5 EAQ88258.1 - 1.7 8.7 6.8 5.5 7.1 6.8 1.8 1 1 0 1 1 1 0 Zinc-finger PHD PF00628.29 EAQ88259.1 - 5.8e-07 29.3 8.3 1.2e-06 28.3 8.3 1.5 1 0 0 1 1 1 1 PHD-finger SET PF00856.28 EAQ88259.1 - 2.6e-05 24.7 0.1 0.00031 21.2 0.0 2.7 2 1 0 2 2 2 1 SET domain E1_DerP2_DerF2 PF02221.15 EAQ88260.1 - 7.7e-11 42.6 0.0 1.2e-10 42.0 0.0 1.3 1 1 0 1 1 1 1 ML domain ATP-synt_F PF01990.17 EAQ88261.1 - 1.6e-25 89.3 0.1 1.9e-25 89.0 0.1 1.1 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit MOSC_N PF03476.16 EAQ88261.1 - 0.0011 18.9 0.0 0.0013 18.7 0.0 1.1 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain DUF2418 PF10332.9 EAQ88262.1 - 1.5e-34 118.3 0.7 2.9e-34 117.5 0.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2418) Aconitase PF00330.20 EAQ88264.1 - 2.3e-159 531.3 0.0 3.1e-159 530.8 0.0 1.2 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EAQ88264.1 - 6.2e-36 123.6 0.0 1.3e-35 122.6 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain Methyltransf_23 PF13489.6 EAQ88266.1 - 5.5e-16 58.8 0.0 8e-16 58.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAQ88266.1 - 2.6e-10 40.9 0.0 9.4e-10 39.1 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EAQ88266.1 - 3.3e-07 31.0 0.0 2e-06 28.4 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EAQ88266.1 - 5.5e-07 30.1 0.0 1.2e-06 29.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAQ88266.1 - 6e-06 26.1 0.0 0.035 13.9 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain FtsJ PF01728.19 EAQ88266.1 - 0.0001 22.4 0.0 0.00016 21.8 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.14 EAQ88266.1 - 0.015 14.9 0.0 0.031 13.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_2 PF00891.18 EAQ88266.1 - 0.017 14.5 0.0 0.027 13.7 0.0 1.4 1 1 0 1 1 1 0 O-methyltransferase domain Ubie_methyltran PF01209.18 EAQ88266.1 - 0.063 12.6 0.0 0.6 9.4 0.0 2.3 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 EAQ88266.1 - 0.065 12.7 0.0 0.26 10.7 0.0 1.9 2 0 0 2 2 2 0 Putative methyltransferase CDC45 PF02724.14 EAQ88268.1 - 5.3e-70 236.5 0.0 3e-59 201.0 0.0 4.8 2 2 2 5 5 5 4 CDC45-like protein Ribosomal_60s PF00428.19 EAQ88268.1 - 1.9 9.1 8.9 6.4 7.4 8.9 2.0 1 0 0 1 1 1 0 60s Acidic ribosomal protein EF-hand_7 PF13499.6 EAQ88269.1 - 2.9e-25 88.5 8.1 1.4e-16 60.7 0.9 3.0 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 EAQ88269.1 - 3.2e-25 85.8 10.3 2.5e-08 32.9 0.2 4.6 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.6 EAQ88269.1 - 1e-24 84.3 3.7 6.6e-07 28.8 0.1 5.2 5 0 0 5 5 5 4 EF-hand domain EF-hand_5 PF13202.6 EAQ88269.1 - 1.3e-18 65.6 11.3 1.5e-05 24.3 0.1 4.6 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.6 EAQ88269.1 - 8.3e-15 54.4 10.5 1.3e-05 24.9 0.8 3.7 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.7 EAQ88269.1 - 6e-09 35.8 5.4 0.0027 17.6 0.1 3.9 2 1 2 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 EAQ88269.1 - 6.8e-05 23.1 0.6 0.0032 17.8 0.1 3.0 2 1 1 3 3 3 2 EF-hand domain SPARC_Ca_bdg PF10591.9 EAQ88269.1 - 0.0002 21.7 2.5 0.45 10.8 0.3 3.1 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 EAQ88269.1 - 0.066 13.1 3.8 0.59 10.0 0.0 3.4 4 1 0 4 4 4 0 EF hand EF-hand_14 PF17959.1 EAQ88269.1 - 0.094 13.1 1.1 7.8 6.9 0.0 3.3 4 0 0 4 4 4 0 EF-hand domain AMP-binding PF00501.28 EAQ88270.1 - 3.2e-85 286.3 0.1 5.1e-85 285.6 0.1 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EAQ88270.1 - 0.00083 20.3 1.0 0.0033 18.4 1.0 2.2 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain CdhD PF03599.16 EAQ88270.1 - 0.071 11.8 0.0 0.13 11.0 0.0 1.3 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase delta subunit Transglut_core PF01841.19 EAQ88271.1 - 1.2e-09 38.6 0.0 2.3e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily Gln_amidase PF15644.6 EAQ88271.1 - 0.0022 19.0 0.0 0.0092 17.0 0.0 2.2 1 1 0 1 1 1 1 Papain fold toxin 1, glutamine deamidase DUF553 PF04473.12 EAQ88271.1 - 0.023 14.3 0.0 2.1 7.9 0.0 2.8 2 1 0 2 2 2 0 Transglutaminase-like domain F-box-like PF12937.7 EAQ88272.1 - 1.3e-05 25.0 0.2 2.8e-05 23.9 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EAQ88272.1 - 5.4e-05 23.0 0.2 0.00013 21.7 0.2 1.7 1 0 0 1 1 1 1 F-box domain Spectrin_like PF18373.1 EAQ88272.1 - 0.045 13.8 0.0 0.22 11.6 0.0 2.2 1 0 0 1 1 1 0 Spectrin like domain F-box_4 PF15966.5 EAQ88272.1 - 0.09 12.7 0.0 0.84 9.5 0.0 2.3 2 0 0 2 2 2 0 F-box PI3K_P85_iSH2 PF16454.5 EAQ88272.1 - 0.14 11.8 0.7 0.28 10.7 0.7 1.4 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain FSA_C PF10479.9 EAQ88272.1 - 0.28 9.3 2.4 0.29 9.2 0.0 1.9 2 0 0 2 2 2 0 Fragile site-associated protein C-terminus Fungal_trans_2 PF11951.8 EAQ88273.1 - 0.0072 15.2 0.2 0.016 14.0 0.2 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Glycos_transf_4 PF00953.21 EAQ88274.1 - 1.4e-33 116.2 9.9 1.4e-33 116.2 9.9 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 4 HTH_psq PF05225.16 EAQ88274.1 - 1.6e-06 27.7 0.1 2.9e-06 26.9 0.1 1.4 1 0 0 1 1 1 1 helix-turn-helix, Psq domain BNR_2 PF13088.6 EAQ88275.1 - 2.9e-06 26.8 0.0 9.2e-05 21.9 0.0 2.2 2 0 0 2 2 2 1 BNR repeat-like domain BNR PF02012.20 EAQ88275.1 - 0.00039 20.0 4.1 0.26 11.4 0.5 3.3 2 0 0 2 2 2 2 BNR/Asp-box repeat Sortilin-Vps10 PF15902.5 EAQ88275.1 - 0.016 14.0 0.0 0.04 12.7 0.0 1.6 1 1 0 1 1 1 0 Sortilin, neurotensin receptor 3, WD40 PF00400.32 EAQ88276.1 - 2.7e-05 24.9 0.6 0.00041 21.1 0.1 2.7 2 0 0 2 2 2 1 WD domain, G-beta repeat CAP_N PF01213.19 EAQ88276.1 - 0.83 9.1 3.5 1.3 8.4 3.5 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal MFS_1 PF07690.16 EAQ88277.1 - 1.5e-18 66.9 14.2 2e-18 66.5 14.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily CDC45 PF02724.14 EAQ88277.1 - 0.24 9.7 9.2 0.33 9.2 9.2 1.1 1 0 0 1 1 1 0 CDC45-like protein RRN3 PF05327.11 EAQ88277.1 - 0.83 8.1 1.7 1.1 7.7 1.7 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Spt5_N PF11942.8 EAQ88277.1 - 1.9 9.5 18.4 3.4 8.7 18.4 1.3 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal NOA36 PF06524.12 EAQ88277.1 - 3.4 6.9 6.0 4.7 6.4 6.0 1.1 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.12 EAQ88277.1 - 7.7 4.6 7.5 11 4.1 7.5 1.1 1 0 0 1 1 1 0 Nop14-like family SAPS PF04499.15 EAQ88278.1 - 7.9 5.1 7.2 14 4.3 7.2 1.4 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein MCM_bind PF09739.9 EAQ88278.1 - 9 4.6 8.7 13 4.1 8.7 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor ThiF PF00899.21 EAQ88281.1 - 1.1e-113 378.6 0.0 1.5e-76 257.0 0.0 2.2 2 0 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 EAQ88281.1 - 8.9e-86 287.9 1.6 1.7e-85 287.0 1.6 1.5 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_FCCH PF16190.5 EAQ88281.1 - 1.3e-31 108.6 0.1 3.4e-31 107.3 0.1 1.8 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_UFD PF09358.10 EAQ88281.1 - 2.2e-31 108.4 0.1 1.3e-29 102.8 0.0 2.5 2 0 0 2 2 2 1 Ubiquitin fold domain E1_4HB PF16191.5 EAQ88281.1 - 1.4e-24 86.0 0.1 4.1e-24 84.5 0.1 1.9 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle GST_N_2 PF13409.6 EAQ88282.1 - 4.3e-19 68.6 0.0 9e-19 67.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Chitin_synth_2 PF03142.15 EAQ88283.1 - 1.7e-112 376.8 9.8 6.5e-66 223.0 0.4 2.2 1 1 1 2 2 2 2 Chitin synthase DEK_C PF08766.11 EAQ88283.1 - 3.5e-15 55.7 0.0 8e-15 54.5 0.0 1.6 2 0 0 2 2 2 1 DEK C terminal domain Glyco_trans_2_3 PF13632.6 EAQ88283.1 - 1.4e-05 25.2 4.7 2e-05 24.6 4.7 1.2 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EAQ88283.1 - 0.00026 21.0 0.0 0.00041 20.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 DUF1353 PF07087.11 EAQ88283.1 - 0.055 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1353) Chitin_synth_2 PF03142.15 EAQ88284.1 - 2.6e-227 755.6 0.0 3.7e-227 755.1 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Cyt-b5 PF00173.28 EAQ88284.1 - 4.7e-16 58.7 0.2 3.2e-09 36.8 0.0 2.9 2 1 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_trans_2_3 PF13632.6 EAQ88284.1 - 1.2e-13 51.5 5.0 1.2e-13 51.5 5.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EAQ88284.1 - 3.3e-12 46.8 0.0 9.3e-12 45.3 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Myosin_head PF00063.21 EAQ88284.1 - 7.6e-08 31.0 0.0 3.4e-07 28.9 0.0 2.0 1 1 0 1 1 1 1 Myosin head (motor domain) Glycos_transf_2 PF00535.26 EAQ88284.1 - 0.00096 19.0 0.0 0.28 11.0 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 EAQ88284.1 - 0.0019 17.7 0.0 0.0049 16.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 21 RIBIOP_C PF04950.12 EAQ88285.1 - 1.3e-93 313.6 0.0 2.2e-93 312.9 0.0 1.3 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 EAQ88285.1 - 4.6e-27 93.9 0.0 1.4e-26 92.4 0.0 1.9 1 0 0 1 1 1 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.27 EAQ88285.1 - 0.032 13.8 0.0 0.066 12.8 0.0 1.5 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain BCDHK_Adom3 PF10436.9 EAQ88286.1 - 2.8e-44 150.8 0.0 5.6e-44 149.8 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 EAQ88286.1 - 3.1e-08 34.1 3.4 6.2e-08 33.1 0.0 2.9 2 1 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Inhibitor_I9 PF05922.16 EAQ88286.1 - 6.8e-06 26.7 0.1 2.1e-05 25.1 0.1 1.8 1 0 0 1 1 1 1 Peptidase inhibitor I9 DUF1681 PF07933.14 EAQ88288.1 - 5e-50 169.0 0.0 6.3e-50 168.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) CAP_N PF01213.19 EAQ88288.1 - 0.9 9.0 4.3 7.4 5.9 0.1 2.4 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Tom5 PF10642.9 EAQ88288.1 - 0.98 9.5 2.7 0.76 9.8 0.6 2.0 2 0 0 2 2 2 0 Mitochondrial import receptor subunit or translocase Dscam_C PF12355.8 EAQ88288.1 - 2.3 9.2 6.0 7.7 7.5 1.3 2.3 2 0 0 2 2 2 0 Down syndrome cell adhesion molecule C terminal IF-2B PF01008.17 EAQ88289.1 - 3.1e-16 59.4 3.6 5.8e-14 52.0 0.7 2.2 1 1 1 2 2 2 2 Initiation factor 2 subunit family ATP-grasp_2 PF08442.10 EAQ88289.1 - 0.017 14.7 0.0 0.033 13.8 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain SpoU_sub_bind PF08032.12 EAQ88289.1 - 0.12 12.7 0.2 0.37 11.1 0.1 2.0 2 0 0 2 2 2 0 RNA 2'-O ribose methyltransferase substrate binding Methyltransf_33 PF10017.9 EAQ88291.1 - 5.8e-60 203.0 0.0 6.8e-60 202.8 0.0 1.0 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent Methyltransf_12 PF08242.12 EAQ88291.1 - 0.063 14.0 0.0 0.14 12.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain FGE-sulfatase PF03781.16 EAQ88292.1 - 9.4e-18 64.7 1.6 2.9e-12 46.7 0.3 2.4 2 0 0 2 2 2 2 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.7 EAQ88292.1 - 3e-06 27.7 0.2 8.5e-06 26.3 0.2 1.8 1 0 0 1 1 1 1 DinB superfamily Methyltransf_33 PF10017.9 EAQ88292.1 - 0.0028 16.8 0.1 0.0045 16.2 0.1 1.3 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent DUF4121 PF13497.6 EAQ88292.1 - 0.16 11.1 0.0 0.25 10.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4121) GFA PF04828.14 EAQ88293.1 - 0.00096 19.4 0.2 0.00096 19.4 0.2 1.7 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme PfkB PF00294.24 EAQ88294.1 - 4.3e-52 177.3 0.5 4.9e-52 177.1 0.5 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase NOA36 PF06524.12 EAQ88295.1 - 0.0058 16.0 2.0 0.011 15.1 2.0 1.3 1 0 0 1 1 1 1 NOA36 protein eIF3_subunit PF08597.10 EAQ88296.1 - 4e-45 154.6 8.8 6e-45 154.0 8.8 1.1 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit Nop53 PF07767.11 EAQ88296.1 - 0.11 11.8 13.2 0.36 10.2 7.0 2.1 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) MDM31_MDM32 PF08118.11 EAQ88297.1 - 1.8e-253 842.0 0.0 2.1e-253 841.7 0.0 1.1 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins Ribosomal_60s PF00428.19 EAQ88297.1 - 0.0082 16.7 6.3 0.2 12.3 0.1 2.7 2 0 0 2 2 2 2 60s Acidic ribosomal protein T6PP_N PF18572.1 EAQ88298.1 - 0.026 14.3 0.0 0.041 13.7 0.0 1.2 1 0 0 1 1 1 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain Rad60-SLD PF11976.8 EAQ88299.1 - 3.3e-13 49.2 0.0 9.3e-13 47.8 0.1 1.7 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like SRP-alpha_N PF04086.13 EAQ88299.1 - 2.9 7.7 13.5 5.1 6.9 13.5 1.4 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal adh_short_C2 PF13561.6 EAQ88300.1 - 1.3e-33 116.5 2.1 2.5e-33 115.6 2.1 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EAQ88300.1 - 1.6e-28 99.5 0.4 2.7e-28 98.8 0.4 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EAQ88300.1 - 2.9e-08 33.8 1.1 8.4e-07 29.1 0.2 2.2 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 EAQ88300.1 - 0.00013 21.6 0.9 0.0011 18.5 0.9 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EAQ88300.1 - 0.014 14.8 0.0 0.04 13.3 0.0 1.8 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase F420_oxidored PF03807.17 EAQ88300.1 - 0.026 15.1 0.4 0.049 14.2 0.4 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 EAQ88300.1 - 0.057 13.5 0.2 0.13 12.3 0.2 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.15 EAQ88300.1 - 0.072 12.2 0.1 0.1 11.7 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein MFS_1 PF07690.16 EAQ88301.1 - 3.7e-33 114.9 24.2 3.7e-33 114.9 24.2 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EAQ88301.1 - 2.2e-07 30.1 14.6 2.2e-07 30.1 14.6 4.3 4 1 0 4 4 4 2 Sugar (and other) transporter FixQ PF05545.11 EAQ88301.1 - 9.6 6.3 11.7 0.11 12.5 0.6 3.2 3 0 0 3 3 3 0 Cbb3-type cytochrome oxidase component FixQ CFEM PF05730.11 EAQ88302.1 - 6.5e-12 45.4 10.0 6.5e-12 45.4 10.0 1.5 2 0 0 2 2 2 1 CFEM domain Sporozoite_P67 PF05642.11 EAQ88302.1 - 0.85 7.6 6.0 0.86 7.6 6.0 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen TFIIA PF03153.13 EAQ88303.1 - 0.17 11.9 7.2 0.21 11.6 7.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit adh_short_C2 PF13561.6 EAQ88305.1 - 3.4e-46 157.7 5.6 1.2e-37 129.7 3.8 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EAQ88305.1 - 6.2e-44 149.8 2.1 8e-44 149.4 2.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EAQ88305.1 - 6.9e-14 52.2 1.3 1.2e-13 51.4 1.3 1.3 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 EAQ88305.1 - 0.00097 19.1 0.6 0.0015 18.5 0.6 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 EAQ88305.1 - 0.0024 18.0 0.2 0.0035 17.4 0.2 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain MobC PF05713.11 EAQ88305.1 - 0.04 14.4 0.1 0.14 12.6 0.1 2.0 1 0 0 1 1 1 0 Bacterial mobilisation protein (MobC) Glycos_transf_2 PF00535.26 EAQ88306.1 - 4.2e-27 95.0 0.0 4.9e-27 94.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EAQ88306.1 - 1.3e-11 44.9 0.0 1.6e-11 44.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 EAQ88306.1 - 3.3e-05 23.5 0.0 3.9e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 EAQ88306.1 - 0.097 12.1 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 21 E1-E2_ATPase PF00122.20 EAQ88307.1 - 1.2e-34 119.4 21.9 4e-29 101.4 0.3 3.2 4 0 0 4 4 4 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 EAQ88307.1 - 1.1e-28 100.2 1.2 1.1e-28 100.2 1.2 2.2 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 EAQ88307.1 - 3.7e-18 65.4 0.0 7.3e-18 64.4 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EAQ88307.1 - 5.5e-18 66.0 0.3 2.1e-13 51.0 0.0 3.4 3 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EAQ88307.1 - 1.2e-13 50.6 0.0 2.9e-13 49.3 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EAQ88307.1 - 1.2e-06 28.5 0.3 7.2e-06 25.9 0.4 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF4775 PF16001.5 EAQ88308.1 - 1.2 8.5 7.2 3.5 6.9 5.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4775) RSN1_7TM PF02714.15 EAQ88310.1 - 2.9e-84 282.6 20.3 7.3e-84 281.3 20.3 1.7 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 EAQ88310.1 - 3.8e-37 128.2 0.0 5.5e-37 127.7 0.0 1.2 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 EAQ88310.1 - 1.6e-36 125.4 4.6 1.6e-36 125.4 4.6 3.0 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport TMA7 PF09072.10 EAQ88311.1 - 1.8e-25 89.5 19.7 2e-25 89.3 19.7 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 Pkinase PF00069.25 EAQ88312.1 - 4.1e-54 183.7 0.0 5.2e-54 183.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ88312.1 - 1.4e-23 83.5 0.0 2.7e-23 82.6 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 EAQ88312.1 - 0.047 13.0 0.0 0.082 12.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EAQ88312.1 - 0.072 12.7 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Pox_ser-thr_kin PF05445.11 EAQ88312.1 - 0.072 12.1 0.0 0.1 11.5 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase PF00069.25 EAQ88313.1 - 2e-52 178.2 0.0 2.5e-52 177.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ88313.1 - 2.5e-30 105.6 0.0 3.1e-30 105.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAQ88313.1 - 0.0017 17.7 0.0 0.0024 17.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EAQ88313.1 - 0.0035 16.7 0.0 0.0054 16.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EAQ88313.1 - 0.028 14.3 0.0 0.051 13.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EAQ88313.1 - 0.034 12.9 0.0 0.051 12.3 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase FTA2 PF13095.6 EAQ88313.1 - 0.09 12.4 0.0 0.53 9.9 0.0 2.0 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 EAQ88313.1 - 0.15 11.0 0.0 0.24 10.3 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain ATP-synt_J PF04911.12 EAQ88314.1 - 0.089 12.4 0.3 0.83 9.3 0.1 2.1 2 0 0 2 2 2 0 ATP synthase j chain MRI PF15325.6 EAQ88315.1 - 0.073 14.2 1.5 0.082 14.0 1.5 1.1 1 0 0 1 1 1 0 Modulator of retrovirus infection AAA_11 PF13086.6 EAQ88316.1 - 0.086 12.6 0.2 6.6 6.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain LEM PF03020.15 EAQ88316.1 - 2.1 8.0 5.5 18 5.0 0.2 3.5 3 0 0 3 3 3 0 LEM domain DUF5082 PF16888.5 EAQ88316.1 - 3 8.2 6.0 7.5 6.9 1.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) BRE1 PF08647.11 EAQ88316.1 - 3.6 7.7 6.4 18 5.5 1.1 2.2 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase ANAPC4_WD40 PF12894.7 EAQ88317.1 - 0.029 14.6 0.1 0.2 12.0 0.0 2.3 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain NINJA_B PF16136.5 EAQ88317.1 - 0.032 14.6 0.8 0.032 14.6 0.8 1.7 2 0 0 2 2 2 0 Putative nuclear localisation signal RVT_1 PF00078.27 EAQ88318.1 - 3.5e-37 128.1 0.0 1.2e-36 126.3 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 EAQ88318.1 - 8.8e-26 90.1 0.0 2.8e-25 88.5 0.0 2.0 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase NB-ARC PF00931.22 EAQ88318.1 - 1.2e-10 41.0 0.1 3.9e-10 39.3 0.0 1.8 2 0 0 2 2 2 1 NB-ARC domain Exo_endo_phos PF03372.23 EAQ88318.1 - 0.0002 21.0 0.3 0.00055 19.5 0.3 1.8 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family TPR_12 PF13424.6 EAQ88318.1 - 0.00028 21.1 0.3 0.023 15.0 0.2 3.6 2 0 0 2 2 2 1 Tetratricopeptide repeat zf-CCHC PF00098.23 EAQ88318.1 - 0.005 16.9 1.7 0.005 16.9 1.7 2.8 3 0 0 3 3 1 1 Zinc knuckle NACHT PF05729.12 EAQ88318.1 - 0.0065 16.4 0.3 0.025 14.5 0.0 2.2 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 EAQ88318.1 - 0.0083 16.5 0.4 0.08 13.3 0.0 3.0 2 0 0 2 2 2 1 AAA ATPase domain SlyX PF04102.12 EAQ88318.1 - 0.012 16.2 5.1 0.11 13.2 5.0 2.7 1 1 1 2 2 2 0 SlyX AAA_25 PF13481.6 EAQ88318.1 - 0.018 14.6 0.1 0.097 12.2 0.1 2.3 1 0 0 1 1 1 0 AAA domain HEPN PF05168.14 EAQ88318.1 - 0.028 14.5 0.1 0.11 12.6 0.1 2.1 1 0 0 1 1 1 0 HEPN domain IstB_IS21 PF01695.17 EAQ88318.1 - 0.035 13.8 0.0 0.11 12.3 0.0 1.8 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF4618 PF15397.6 EAQ88318.1 - 0.1 12.0 4.1 2.8 7.3 1.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) HMMR_N PF15905.5 EAQ88318.1 - 0.14 11.6 0.4 0.29 10.5 0.4 1.4 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal CorA PF01544.18 EAQ88318.1 - 0.15 11.4 1.5 0.32 10.3 1.5 1.5 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein PKcGMP_CC PF16808.5 EAQ88318.1 - 0.72 9.7 2.7 0.69 9.8 0.3 2.2 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Exonuc_VII_L PF02601.15 EAQ88318.1 - 1 8.8 4.5 3.5 7.1 4.5 1.9 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF3584 PF12128.8 EAQ88318.1 - 1.1 6.7 5.6 2 5.8 5.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) CENP-F_leu_zip PF10473.9 EAQ88318.1 - 4.5 7.3 6.7 0.42 10.6 0.6 2.3 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Rax2 PF12768.7 EAQ88319.1 - 0.0057 16.1 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 Cortical protein marker for cell polarity FAD_binding_4 PF01565.23 EAQ88320.1 - 2.9e-18 65.9 0.8 5.9e-18 65.0 0.8 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EAQ88320.1 - 2.6e-09 37.0 0.0 6.8e-09 35.7 0.0 1.8 1 0 0 1 1 1 1 Berberine and berberine like TauD PF02668.16 EAQ88322.1 - 1.1e-39 136.9 0.4 1.4e-39 136.5 0.4 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Radical_SAM PF04055.21 EAQ88325.1 - 2.4e-10 41.1 0.0 3.9e-10 40.4 0.0 1.4 1 1 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 EAQ88325.1 - 2.2e-07 31.2 0.0 3.6e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 EAQ88325.1 - 4.6e-05 23.5 0.0 0.00017 21.7 0.0 1.8 2 0 0 2 2 2 1 4Fe-4S single cluster domain ADK PF00406.22 EAQ88326.1 - 1.2e-08 35.2 0.0 2.9e-07 30.7 0.0 2.0 1 1 1 2 2 2 1 Adenylate kinase AAA_17 PF13207.6 EAQ88326.1 - 3.7e-08 33.9 0.1 2.3e-07 31.3 0.0 2.0 1 1 1 2 2 2 1 AAA domain AAA PF00004.29 EAQ88326.1 - 0.03 14.7 0.0 0.031 14.7 0.0 1.2 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Thymidylate_kin PF02223.17 EAQ88326.1 - 0.036 13.8 0.0 0.13 11.9 0.0 1.9 1 1 2 3 3 3 0 Thymidylate kinase AAA_18 PF13238.6 EAQ88326.1 - 0.091 13.3 0.0 0.17 12.4 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EAQ88326.1 - 0.16 12.1 0.0 0.38 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 EAQ88326.1 - 0.23 11.2 0.0 0.3 10.8 0.0 1.2 1 0 0 1 1 1 0 Cytidylate kinase Dimer_Tnp_hAT PF05699.14 EAQ88327.1 - 5.2e-16 58.2 0.1 1.2e-15 57.0 0.1 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region MMR_HSR1 PF01926.23 EAQ88328.1 - 1.5e-07 31.5 0.0 2.8e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EAQ88328.1 - 2.7e-05 24.2 0.1 9.3e-05 22.4 0.0 1.8 2 0 0 2 2 2 1 RsgA GTPase AIG1 PF04548.16 EAQ88328.1 - 4.5e-05 22.9 0.0 6.6e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 EAQ88328.1 - 0.0014 18.7 0.0 0.0035 17.4 0.0 1.8 1 0 0 1 1 1 1 Dynamin family AAA_22 PF13401.6 EAQ88328.1 - 0.0018 18.6 0.0 0.0034 17.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 EAQ88328.1 - 0.0044 17.5 0.3 0.0093 16.5 0.3 1.5 1 0 0 1 1 1 1 ABC transporter AAA_7 PF12775.7 EAQ88328.1 - 0.0064 16.0 0.5 0.023 14.2 0.2 1.9 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_16 PF13191.6 EAQ88328.1 - 0.0087 16.5 0.1 0.018 15.4 0.1 1.4 1 0 0 1 1 1 1 AAA ATPase domain Ploopntkinase3 PF18751.1 EAQ88328.1 - 0.017 15.1 0.0 0.027 14.4 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 PduV-EutP PF10662.9 EAQ88328.1 - 0.031 14.0 0.1 0.06 13.1 0.1 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation T2SSE PF00437.20 EAQ88328.1 - 0.05 12.6 0.3 0.084 11.9 0.3 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein FeoB_N PF02421.18 EAQ88328.1 - 0.054 13.0 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B Roc PF08477.13 EAQ88328.1 - 0.058 13.6 0.5 0.14 12.4 0.1 1.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Zeta_toxin PF06414.12 EAQ88328.1 - 0.073 12.3 0.1 0.13 11.5 0.1 1.3 1 0 0 1 1 1 0 Zeta toxin PIF1 PF05970.14 EAQ88328.1 - 0.12 11.6 0.2 0.2 10.8 0.2 1.2 1 0 0 1 1 1 0 PIF1-like helicase AAA_25 PF13481.6 EAQ88328.1 - 0.12 12.0 0.3 0.41 10.2 0.3 1.9 1 0 0 1 1 1 0 AAA domain Septin PF00735.18 EAQ88328.1 - 0.21 10.9 0.1 0.38 10.0 0.1 1.4 1 0 0 1 1 1 0 Septin DUF815 PF05673.13 EAQ88328.1 - 0.22 10.6 0.2 0.35 10.0 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) NAD_binding_1 PF00175.21 EAQ88329.1 - 1.8e-25 89.7 0.0 2.9e-25 89.0 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 EAQ88329.1 - 6.7e-16 58.5 0.0 1.1e-15 57.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 EAQ88329.1 - 2.3e-09 37.5 0.0 9.2e-05 22.6 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain DEAD PF00270.29 EAQ88330.1 - 1.8e-43 148.3 0.1 3.2e-43 147.5 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EAQ88330.1 - 2e-17 63.5 0.0 1e-16 61.3 0.0 2.2 2 1 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EAQ88330.1 - 3.8e-13 49.4 0.1 7.9e-13 48.4 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 EAQ88330.1 - 0.00091 19.3 0.0 0.0019 18.3 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Kelch_5 PF13854.6 EAQ88331.1 - 1.3e-11 44.2 4.0 7.8e-10 38.5 0.6 3.7 4 0 0 4 4 4 1 Kelch motif Kelch_6 PF13964.6 EAQ88331.1 - 2.6e-06 27.5 12.6 0.62 10.4 0.5 6.1 5 2 1 6 6 6 3 Kelch motif Kelch_2 PF07646.15 EAQ88331.1 - 0.00062 19.6 2.8 16 5.6 0.0 5.7 6 0 0 6 6 6 0 Kelch motif Kelch_3 PF13415.6 EAQ88331.1 - 0.0013 19.0 6.7 0.052 13.9 0.1 5.0 5 0 0 5 5 5 1 Galactose oxidase, central domain Alpha_GJ PF03229.13 EAQ88331.1 - 0.0025 18.3 1.8 0.0054 17.3 1.8 1.5 1 0 0 1 1 1 1 Alphavirus glycoprotein J Gram_pos_anchor PF00746.21 EAQ88331.1 - 0.027 14.4 1.1 0.14 12.2 1.1 2.3 1 1 0 1 1 1 0 LPXTG cell wall anchor motif Yip1 PF04893.17 EAQ88331.1 - 0.035 13.8 0.0 0.07 12.8 0.0 1.4 1 0 0 1 1 1 0 Yip1 domain Kelch_4 PF13418.6 EAQ88331.1 - 0.044 13.8 0.5 0.044 13.8 0.5 6.2 6 1 0 6 6 6 0 Galactose oxidase, central domain EphA2_TM PF14575.6 EAQ88331.1 - 0.044 14.7 0.0 0.077 13.9 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Phage_HK97_TLTM PF06120.11 EAQ88331.1 - 0.045 12.9 0.1 0.075 12.2 0.1 1.2 1 0 0 1 1 1 0 Tail length tape measure protein DUF533 PF04391.12 EAQ88331.1 - 0.2 11.2 0.1 0.34 10.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF533) SelP_N PF04592.14 EAQ88331.1 - 0.51 9.7 7.8 0.79 9.1 7.8 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Pex14_N PF04695.13 EAQ88331.1 - 1.6 9.4 12.5 12 6.5 7.4 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region C2-set_2 PF08205.12 EAQ88332.1 - 0.17 12.0 0.2 17 5.6 0.0 2.4 2 0 0 2 2 2 0 CD80-like C2-set immunoglobulin domain Ank_2 PF12796.7 EAQ88334.1 - 2e-45 153.3 0.1 4.3e-07 30.4 0.0 7.8 6 2 2 8 8 8 7 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAQ88334.1 - 2.3e-37 122.7 15.4 4.5e-07 29.7 0.0 13.3 14 0 0 14 14 14 7 Ankyrin repeat Ank PF00023.30 EAQ88334.1 - 1.6e-36 123.2 21.0 1.1e-06 28.8 0.0 12.8 13 1 0 13 13 13 6 Ankyrin repeat Ank_4 PF13637.6 EAQ88334.1 - 3.4e-34 116.8 5.3 1e-05 26.0 0.0 9.5 8 1 1 9 9 9 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAQ88334.1 - 2.8e-28 97.6 9.3 7.1e-07 29.4 0.0 9.3 7 3 3 10 10 10 6 Ankyrin repeats (many copies) F-box-like PF12937.7 EAQ88334.1 - 9.4e-05 22.2 0.0 0.00027 20.7 0.0 1.8 1 0 0 1 1 1 1 F-box-like GLTP PF08718.11 EAQ88335.1 - 1.6e-46 158.3 0.1 7.9e-46 156.0 0.1 1.8 2 0 0 2 2 2 1 Glycolipid transfer protein (GLTP) PLDc PF00614.22 EAQ88336.1 - 3.6e-16 58.6 1.4 1.5e-07 31.3 0.1 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 EAQ88336.1 - 3.2e-14 53.0 0.0 3.1e-05 23.9 0.0 3.7 3 1 0 3 3 3 3 PLD-like domain HET PF06985.11 EAQ88337.1 - 6.5e-23 81.7 0.0 1.7e-22 80.4 0.0 1.7 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Glyco_hydro_7 PF00840.20 EAQ88339.1 - 1.1e-15 57.4 0.0 1.8e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 CBM_1 PF00734.18 EAQ88339.1 - 2.1e-11 43.6 10.4 2.1e-11 43.6 10.4 2.7 3 0 0 3 3 3 1 Fungal cellulose binding domain Init_tRNA_PT PF04179.12 EAQ88339.1 - 0.11 12.8 0.5 4.3 7.7 0.1 2.2 2 0 0 2 2 2 0 Rit1 DUSP-like domain SPACA7 PF15307.6 EAQ88339.1 - 0.19 12.0 0.1 0.48 10.7 0.0 1.7 2 0 0 2 2 2 0 Sperm acrosome-associated protein 7 adh_short PF00106.25 EAQ88340.1 - 3e-18 66.0 0.0 4.9e-18 65.3 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EAQ88340.1 - 5.3e-10 39.5 0.0 8.5e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 EAQ88340.1 - 1.4e-06 28.0 0.0 2.6e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase SNF5 PF04855.12 EAQ88341.1 - 6.2e-88 294.6 0.0 8.1e-88 294.2 0.0 1.1 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 GATA PF00320.27 EAQ88341.1 - 1.3e-06 27.8 1.8 3e-06 26.7 1.8 1.7 1 0 0 1 1 1 1 GATA zinc finger Rubredoxin_2 PF18073.1 EAQ88341.1 - 0.034 13.9 6.6 0.46 10.2 2.1 2.6 2 0 0 2 2 2 0 Rubredoxin metal binding domain DUF4139 PF13598.6 EAQ88343.1 - 2e-35 122.4 0.1 4.9e-35 121.1 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4139) DUF4140 PF13600.6 EAQ88343.1 - 3e-28 98.1 2.9 3e-28 98.1 2.9 3.9 3 1 0 3 3 3 1 N-terminal domain of unknown function (DUF4140) YL1 PF05764.13 EAQ88343.1 - 0.039 14.1 20.7 0.086 12.9 20.7 1.6 1 0 0 1 1 1 0 YL1 nuclear protein Nucleoporin_FG PF13634.6 EAQ88343.1 - 0.048 14.5 18.7 0.14 13.0 12.9 2.9 1 1 1 2 2 2 0 Nucleoporin FG repeat region DUF3157 PF11355.8 EAQ88343.1 - 0.17 11.4 2.2 0.54 9.8 2.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3157) Cluap1 PF10234.9 EAQ88343.1 - 1.3 8.4 16.5 2.6 7.4 16.5 1.4 1 0 0 1 1 1 0 Clusterin-associated protein-1 Tho2 PF11262.8 EAQ88343.1 - 1.4 8.0 11.8 1.2 8.2 4.8 2.3 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 HBS1_N PF08938.10 EAQ88343.1 - 4.8 7.6 9.8 3.5 8.0 5.9 2.4 2 0 0 2 2 2 0 HBS1 N-terminus Plasmodium_Vir PF05795.11 EAQ88344.1 - 0.081 12.3 0.1 0.21 11.0 0.0 1.7 2 0 0 2 2 2 0 Plasmodium vivax Vir protein Keratin_2_head PF16208.5 EAQ88344.1 - 1.2 9.3 20.9 1.3 9.2 19.0 1.8 2 0 0 2 2 2 0 Keratin type II head KRTAP PF11759.8 EAQ88344.1 - 9.1 6.9 32.4 1.3 9.6 5.0 2.2 2 0 0 2 2 2 0 Keratin-associated matrix LPMO_10 PF03067.15 EAQ88346.1 - 4.4e-13 50.3 2.4 6.5e-13 49.8 2.4 1.3 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Glyco_hydro_61 PF03443.14 EAQ88346.1 - 0.0072 16.3 0.2 0.26 11.2 0.0 2.2 2 0 0 2 2 2 2 Glycosyl hydrolase family 61 Alpha-amylase PF00128.24 EAQ88347.1 - 3.3e-23 82.8 0.2 8.1e-23 81.5 0.2 1.6 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.18 EAQ88347.1 - 8.5e-12 45.4 0.1 2.2e-11 44.1 0.1 1.6 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Glyco_hydro_61 PF03443.14 EAQ88348.1 - 6.8e-31 107.8 0.0 9e-31 107.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Pectate_lyase_3 PF12708.7 EAQ88349.1 - 1.3e-24 87.3 0.2 1.3e-24 87.3 0.2 1.9 2 0 0 2 2 2 1 Pectate lyase superfamily protein ABM PF03992.16 EAQ88351.1 - 0.00093 19.3 1.9 0.014 15.5 0.0 2.7 3 0 0 3 3 3 1 Antibiotic biosynthesis monooxygenase tRNA-synt_1c PF00749.21 EAQ88352.1 - 2.3e-98 329.0 0.0 3.1e-98 328.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 EAQ88352.1 - 2.4e-35 122.0 0.0 1.3e-34 119.5 0.0 2.2 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain Macro PF01661.21 EAQ88354.1 - 1.1e-36 125.5 0.0 1.6e-36 124.9 0.0 1.3 1 0 0 1 1 1 1 Macro domain ABC_tran PF00005.27 EAQ88355.1 - 8.2e-47 159.2 0.4 1.2e-22 80.9 0.1 3.7 2 2 0 2 2 2 2 ABC transporter 4HB PF17947.1 EAQ88355.1 - 7.4e-32 109.2 0.9 2e-31 107.9 0.1 2.3 2 0 0 2 2 1 1 Four helical bundle domain AAA_21 PF13304.6 EAQ88355.1 - 1.5e-16 61.1 0.2 0.0024 17.7 0.0 5.2 4 1 0 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EAQ88355.1 - 2.9e-15 56.3 1.3 6.2e-05 22.5 0.0 4.1 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EAQ88355.1 - 1.2e-08 34.5 0.1 0.0043 16.8 0.0 3.0 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EAQ88355.1 - 1.2e-07 31.9 0.2 0.0021 18.1 0.0 3.1 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.6 EAQ88355.1 - 2e-07 31.8 10.6 0.0017 18.9 0.2 3.7 4 0 0 4 4 3 2 AAA domain RsgA_GTPase PF03193.16 EAQ88355.1 - 3.5e-07 30.3 0.0 0.0047 16.8 0.0 2.8 2 0 0 2 2 2 2 RsgA GTPase AAA_28 PF13521.6 EAQ88355.1 - 5.5e-07 30.0 0.1 0.0063 16.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 EAQ88355.1 - 1.1e-06 29.0 0.3 0.0064 16.8 0.0 3.6 4 0 0 4 4 3 1 AAA domain Dynamin_N PF00350.23 EAQ88355.1 - 2.4e-06 27.7 0.0 0.00024 21.2 0.0 2.8 2 0 0 2 2 2 1 Dynamin family MeaB PF03308.16 EAQ88355.1 - 6.3e-06 25.4 0.3 0.081 11.9 0.0 3.0 3 0 0 3 3 3 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 EAQ88355.1 - 9.9e-06 26.0 2.1 0.82 10.0 0.0 4.5 5 0 0 5 5 4 1 AAA ATPase domain AAA_15 PF13175.6 EAQ88355.1 - 1.2e-05 25.3 0.1 0.043 13.5 0.0 2.9 2 0 0 2 2 2 2 AAA ATPase domain AAA_18 PF13238.6 EAQ88355.1 - 2.7e-05 24.7 0.1 0.15 12.6 0.1 3.1 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 EAQ88355.1 - 8.7e-05 22.7 0.0 0.55 10.4 0.0 2.9 2 0 0 2 2 2 2 AAA domain PduV-EutP PF10662.9 EAQ88355.1 - 9.9e-05 22.1 0.0 0.075 12.8 0.0 2.7 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation DUF87 PF01935.17 EAQ88355.1 - 0.00038 20.6 0.2 0.24 11.5 0.1 3.3 3 0 0 3 3 2 1 Helicase HerA, central domain RNA_helicase PF00910.22 EAQ88355.1 - 0.00046 20.5 0.0 1.4 9.4 0.0 2.8 2 0 0 2 2 2 1 RNA helicase AAA_27 PF13514.6 EAQ88355.1 - 0.00046 19.8 0.1 0.093 12.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 EAQ88355.1 - 0.0007 19.6 0.2 0.19 11.6 0.0 2.6 2 0 0 2 2 2 1 NACHT domain G-alpha PF00503.20 EAQ88355.1 - 0.00073 18.8 0.2 0.89 8.6 0.0 2.6 2 0 0 2 2 2 2 G-protein alpha subunit AAA PF00004.29 EAQ88355.1 - 0.00099 19.5 0.0 0.62 10.5 0.0 3.9 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 EAQ88355.1 - 0.0019 17.9 0.1 3.1 7.5 0.0 3.2 3 0 0 3 3 3 1 AAA domain MMS19_N PF14500.6 EAQ88355.1 - 0.0042 16.7 1.2 1.2 8.7 0.0 3.2 1 1 2 3 3 3 1 Dos2-interacting transcription regulator of RNA-Pol-II ParcG PF10274.9 EAQ88355.1 - 0.0053 16.9 0.7 10 6.2 0.1 3.2 1 1 1 3 3 3 0 Parkin co-regulated protein AAA_30 PF13604.6 EAQ88355.1 - 0.006 16.3 0.0 3.1 7.5 0.0 3.2 2 0 0 2 2 2 1 AAA domain Septin PF00735.18 EAQ88355.1 - 0.0079 15.5 0.7 3.1 7.0 0.0 3.2 3 0 0 3 3 3 1 Septin cobW PF02492.19 EAQ88355.1 - 0.008 15.8 0.5 2.1 7.9 0.0 3.1 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.22 EAQ88355.1 - 0.013 14.7 0.7 0.39 9.9 0.0 2.7 3 0 0 3 3 3 0 NB-ARC domain Roc PF08477.13 EAQ88355.1 - 0.014 15.6 0.1 10 6.4 0.0 3.0 3 1 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase PRK PF00485.18 EAQ88355.1 - 0.014 15.2 0.0 0.78 9.4 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family CLP1_P PF16575.5 EAQ88355.1 - 0.02 14.7 0.0 0.79 9.5 0.0 2.6 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Zeta_toxin PF06414.12 EAQ88355.1 - 0.021 14.1 0.1 3.6 6.8 0.0 2.8 2 0 0 2 2 2 0 Zeta toxin ATP-synt_ab PF00006.25 EAQ88355.1 - 0.023 14.4 0.3 8.8 5.9 0.0 2.8 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF815 PF05673.13 EAQ88355.1 - 0.026 13.7 0.0 5.6 6.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) SbcCD_C PF13558.6 EAQ88355.1 - 0.032 14.5 0.0 3.8 7.8 0.0 3.3 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Ploopntkinase3 PF18751.1 EAQ88355.1 - 0.035 14.0 0.1 11 5.9 0.0 2.5 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 Rad17 PF03215.15 EAQ88355.1 - 0.037 14.0 0.0 4.4 7.2 0.0 2.7 3 0 0 3 3 2 0 Rad17 P-loop domain ATP_bind_1 PF03029.17 EAQ88355.1 - 0.043 13.6 0.4 7.3 6.3 0.0 3.0 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_13 PF13166.6 EAQ88355.1 - 0.047 12.3 2.2 2.7 6.5 0.0 3.1 4 0 0 4 4 3 0 AAA domain MukB PF04310.12 EAQ88355.1 - 0.054 13.3 0.1 6.7 6.4 0.0 2.8 3 0 0 3 3 3 0 MukB N-terminal IstB_IS21 PF01695.17 EAQ88355.1 - 0.064 13.0 0.0 5.3 6.7 0.0 2.7 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_25 PF13481.6 EAQ88355.1 - 0.065 12.8 0.0 5.3 6.6 0.0 2.9 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 EAQ88355.1 - 0.069 12.5 0.6 1.7 8.0 0.0 2.7 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_7 PF12775.7 EAQ88355.1 - 0.074 12.6 0.0 4.8 6.7 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region FeoB_N PF02421.18 EAQ88355.1 - 0.088 12.3 0.2 0.82 9.2 0.1 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B MobB PF03205.14 EAQ88355.1 - 0.11 12.3 0.1 6.6 6.6 0.0 2.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Glyco_hydro_12 PF01670.16 EAQ88356.1 - 7e-63 212.5 13.9 8.2e-63 212.2 13.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 TonB_2 PF13103.6 EAQ88356.1 - 0.13 12.5 0.0 0.28 11.5 0.0 1.5 1 0 0 1 1 1 0 TonB C terminal Methyltransf_2 PF00891.18 EAQ88358.1 - 4.3e-20 71.9 0.0 6.1e-20 71.4 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain HipA_C PF07804.12 EAQ88358.1 - 0.035 13.8 0.0 0.1 12.3 0.0 1.7 2 0 0 2 2 2 0 HipA-like C-terminal domain Fungal_trans PF04082.18 EAQ88359.1 - 6.3e-13 48.4 0.4 1e-12 47.7 0.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EAQ88359.1 - 5.5e-08 32.8 10.6 1e-07 32.0 10.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EAQ88360.1 - 5.4e-14 51.9 0.0 9.2e-14 51.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EAQ88360.1 - 2e-08 34.2 8.9 4.2e-08 33.2 8.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_9 PF13371.6 EAQ88361.1 - 0.00027 21.0 0.6 0.0017 18.5 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat Tom5 PF10642.9 EAQ88361.1 - 0.073 13.1 2.7 0.17 11.9 0.0 2.9 2 0 0 2 2 2 0 Mitochondrial import receptor subunit or translocase CDH-cyt PF16010.5 EAQ88362.1 - 2.9e-06 27.1 0.1 1.9e-05 24.4 0.0 2.0 2 0 0 2 2 2 1 Cytochrome domain of cellobiose dehydrogenase Cytochrom_B561 PF03188.16 EAQ88362.1 - 0.00079 19.6 2.8 0.00079 19.6 2.8 1.9 1 1 0 1 1 1 1 Eukaryotic cytochrome b561 Rax2 PF12768.7 EAQ88362.1 - 0.038 13.5 0.0 0.15 11.5 0.1 1.8 2 0 0 2 2 2 0 Cortical protein marker for cell polarity GpcrRhopsn4 PF10192.9 EAQ88362.1 - 0.047 13.1 0.4 0.09 12.2 0.4 1.4 1 0 0 1 1 1 0 Rhodopsin-like GPCR transmembrane domain TMEM252 PF15664.5 EAQ88362.1 - 0.067 12.9 0.1 0.13 12.0 0.1 1.4 1 0 0 1 1 1 0 Transmembrane protein 252 family DUF2417 PF10329.9 EAQ88362.1 - 0.076 12.4 3.9 0.2 11.1 0.9 2.1 1 1 1 2 2 2 0 Region of unknown function (DUF2417) YajC PF02699.15 EAQ88362.1 - 0.078 12.9 0.1 0.34 10.8 0.0 2.0 2 0 0 2 2 2 0 Preprotein translocase subunit EphA2_TM PF14575.6 EAQ88362.1 - 0.43 11.5 1.4 5.5 8.0 0.0 2.9 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF4199 PF13858.6 EAQ88362.1 - 0.95 9.8 5.2 1.3 9.4 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF4199) Ni_hydr_CYTB PF01292.20 EAQ88362.1 - 1.2 8.7 12.1 1.6 8.3 7.0 2.9 1 1 2 3 3 3 0 Prokaryotic cytochrome b561 Saf_2TM PF18303.1 EAQ88362.1 - 1.9 8.1 4.4 2.6 7.6 0.3 2.3 1 1 0 2 2 2 0 SAVED-fused 2TM effector domain Abhydrolase_3 PF07859.13 EAQ88363.1 - 4.5e-14 52.8 0.0 3.9e-10 40.0 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold TMEM154 PF15102.6 EAQ88365.1 - 0.0021 18.0 0.2 0.0021 18.0 0.2 1.8 2 1 1 3 3 3 1 TMEM154 protein family EphA2_TM PF14575.6 EAQ88365.1 - 0.032 15.1 0.0 0.079 13.8 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain FixQ PF05545.11 EAQ88365.1 - 0.11 12.5 0.4 0.18 11.8 0.4 1.3 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ DDE_1 PF03184.19 EAQ88366.1 - 1.6e-27 96.3 0.0 2.8e-27 95.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.16 EAQ88366.1 - 2.7e-09 36.6 0.0 6.6e-09 35.4 0.0 1.7 1 0 0 1 1 1 1 helix-turn-helix, Psq domain DDE_3 PF13358.6 EAQ88366.1 - 2.4e-05 24.2 0.1 0.0076 16.0 0.0 3.1 3 0 0 3 3 3 1 DDE superfamily endonuclease SpoIIID PF12116.8 EAQ88366.1 - 0.049 13.7 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Stage III sporulation protein D ZapB PF06005.12 EAQ88366.1 - 0.1 13.1 1.3 0.64 10.5 1.0 2.7 2 0 0 2 2 2 0 Cell division protein ZapB Promethin PF16015.5 EAQ88367.1 - 0.016 15.1 0.9 0.016 15.1 0.9 2.2 2 0 0 2 2 2 0 Promethin DUF2157 PF09925.9 EAQ88367.1 - 1 9.1 8.2 8.1 6.2 3.7 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2157) PPR_2 PF13041.6 EAQ88369.1 - 7.9e-40 134.8 9.8 4.3e-08 33.2 0.0 13.3 12 4 5 17 17 17 8 PPR repeat family PPR_3 PF13812.6 EAQ88369.1 - 5.4e-26 90.5 0.1 0.0084 16.2 0.0 11.0 11 1 1 12 12 12 5 Pentatricopeptide repeat domain PPR PF01535.20 EAQ88369.1 - 3.5e-20 70.8 27.6 0.0012 19.0 0.1 12.9 17 0 0 17 17 17 5 PPR repeat PPR_1 PF12854.7 EAQ88369.1 - 3.8e-17 61.7 0.1 1.4e-07 31.1 0.0 8.2 9 0 0 9 9 9 2 PPR repeat PPR_long PF17177.4 EAQ88369.1 - 1.3e-11 44.3 18.8 5.1e-06 26.0 0.1 7.0 2 2 6 9 9 9 5 Pentacotripeptide-repeat region of PRORP RPM2 PF08579.11 EAQ88369.1 - 0.0007 20.0 0.0 0.0093 16.4 0.0 3.0 3 1 1 4 4 4 1 Mitochondrial ribonuclease P subunit (RPM2) ATP13 PF12921.7 EAQ88369.1 - 0.0018 18.1 0.9 0.068 13.0 0.5 3.2 1 1 1 2 2 2 1 Mitochondrial ATPase expression GHMP_kinases_N PF00288.26 EAQ88370.1 - 2.2e-16 59.8 1.6 2.2e-16 59.8 1.6 2.4 3 0 0 3 3 3 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EAQ88370.1 - 8.3e-09 35.7 0.0 1.7e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 GHMP kinases C terminal DUF4253 PF14062.6 EAQ88370.1 - 0.15 12.2 0.0 0.7 10.1 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4253) Aldedh PF00171.22 EAQ88372.1 - 1.2e-130 436.2 0.0 1.3e-130 436.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 EAQ88372.1 - 9.9e-05 21.5 0.0 0.00018 20.7 0.0 1.6 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) RRM_1 PF00076.22 EAQ88373.1 - 1.1e-08 34.8 0.1 3.1e-06 26.9 0.1 2.4 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SDA1 PF05285.12 EAQ88373.1 - 0.03 13.8 6.5 0.032 13.7 6.5 1.2 1 0 0 1 1 1 0 SDA1 Trypan_PARP PF05887.11 EAQ88373.1 - 0.49 10.4 5.9 0.68 9.9 5.9 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Nop14 PF04147.12 EAQ88373.1 - 0.7 8.0 9.1 0.8 7.8 9.1 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 EAQ88373.1 - 2.8 6.1 5.3 2.6 6.2 5.3 1.1 1 0 0 1 1 1 0 CDC45-like protein NMD3 PF04981.13 EAQ88374.1 - 6.9e-77 258.2 3.6 1.1e-76 257.6 3.6 1.3 1 0 0 1 1 1 1 NMD3 family TPR_1 PF00515.28 EAQ88374.1 - 2e-05 24.2 0.1 0.14 12.0 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 EAQ88374.1 - 4.5e-05 23.0 0.2 0.00066 19.3 0.1 2.4 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.17 EAQ88374.1 - 9.1e-05 22.3 3.8 0.042 14.0 0.0 4.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 EAQ88374.1 - 0.00016 21.9 0.2 0.00052 20.2 0.2 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.6 EAQ88374.1 - 0.017 15.1 0.8 3.2 8.0 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat HypA PF01155.19 EAQ88374.1 - 0.08 13.0 1.5 4.7 7.3 0.1 2.6 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Ead_Ea22 PF13935.6 EAQ88374.1 - 0.084 13.5 6.2 1.2 9.8 2.0 2.5 2 0 0 2 2 2 0 Ead/Ea22-like protein DUF4295 PF14128.6 EAQ88374.1 - 0.17 11.7 1.9 0.21 11.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4295) HAD_2 PF13419.6 EAQ88375.1 - 1.8e-07 31.4 0.0 1.3e-06 28.7 0.0 2.0 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EAQ88375.1 - 0.028 14.7 0.0 3.5 7.9 0.0 2.2 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase ADH_zinc_N PF00107.26 EAQ88376.1 - 5.7e-20 71.6 0.0 1.2e-19 70.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EAQ88376.1 - 1.5e-13 51.9 0.0 3e-13 51.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Zn_clus PF00172.18 EAQ88376.1 - 2e-06 27.8 11.7 2e-06 27.8 11.7 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_N PF08240.12 EAQ88376.1 - 4.5e-06 26.5 0.3 0.00024 20.9 0.0 3.1 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Fungal_trans_2 PF11951.8 EAQ88376.1 - 9.4e-06 24.7 0.0 1.3e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain WD40 PF00400.32 EAQ88377.1 - 1.1e-09 38.7 0.7 0.0086 16.9 0.0 4.1 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAQ88377.1 - 0.03 14.6 0.0 8.1 6.8 0.0 2.9 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain SOG2 PF10428.9 EAQ88377.1 - 0.96 8.6 5.8 1.4 8.0 5.8 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Acyltransferase PF01553.21 EAQ88378.1 - 2.7e-18 65.9 0.0 6.5e-18 64.6 0.0 1.6 1 0 0 1 1 1 1 Acyltransferase UPF0086 PF01868.16 EAQ88379.1 - 1.1e-30 105.3 0.6 1.6e-30 104.8 0.6 1.2 1 0 0 1 1 1 1 Domain of unknown function UPF0086 DUF3123 PF11321.8 EAQ88379.1 - 0.29 11.8 2.1 0.5 11.0 2.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3123) Pantoate_ligase PF02569.15 EAQ88380.1 - 1.3e-34 119.6 0.0 1.6e-34 119.4 0.0 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase Peptidase_S10 PF00450.22 EAQ88381.1 - 6.9e-42 144.3 0.0 1.2e-40 140.2 0.0 2.1 1 1 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.7 EAQ88381.1 - 3e-05 24.7 2.8 4.2e-05 24.3 2.3 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 EAQ88381.1 - 0.011 15.2 0.0 0.055 12.9 0.1 1.9 2 0 0 2 2 2 0 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 EAQ88381.1 - 0.23 10.7 0.0 0.47 9.7 0.0 1.5 2 0 0 2 2 2 0 Serine aminopeptidase, S33 DUF1772 PF08592.11 EAQ88383.1 - 0.0027 18.0 1.1 0.0039 17.5 1.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) DUF1003 PF06210.11 EAQ88383.1 - 0.12 12.5 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1003) ZipA_C PF04354.13 EAQ88383.1 - 0.13 12.2 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 ZipA, C-terminal FtsZ-binding domain RE_XamI PF09572.10 EAQ88383.1 - 0.25 11.0 0.9 0.32 10.7 0.9 1.1 1 0 0 1 1 1 0 XamI restriction endonuclease DUF3824 PF12868.7 EAQ88383.1 - 0.48 11.1 6.4 0.68 10.6 6.4 1.3 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) Casc1_N PF15927.5 EAQ88383.1 - 0.73 9.5 6.8 1 9.0 6.8 1.1 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus PepSY_2 PF13670.6 EAQ88383.1 - 1.7 8.7 7.9 0.066 13.2 2.3 1.6 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain Pre-PUA PF17832.1 EAQ88384.1 - 4.9e-19 68.8 0.4 7.6e-19 68.2 0.4 1.3 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 EAQ88384.1 - 1.2e-13 50.8 0.4 4.4e-06 26.6 0.0 2.3 2 0 0 2 2 2 2 PUA domain Inhibitor_I78 PF11720.8 EAQ88385.1 - 1e-08 35.1 0.0 1.1e-08 35.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase inhibitor I78 family potato_inhibit PF00280.18 EAQ88385.1 - 0.0025 18.4 0.2 0.0038 17.9 0.2 1.4 1 1 0 1 1 1 1 Potato inhibitor I family DUF2924 PF11149.8 EAQ88385.1 - 0.018 15.4 0.1 0.021 15.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2924) Cytomega_gL PF01801.16 EAQ88385.1 - 0.066 12.6 0.0 0.073 12.5 0.0 1.0 1 0 0 1 1 1 0 Cytomegalovirus glycoprotein L NST1 PF13945.6 EAQ88388.1 - 1.5e-54 185.0 3.2 1.5e-54 185.0 3.2 4.4 2 2 2 4 4 4 1 Salt tolerance down-regulator Ras PF00071.22 EAQ88390.1 - 3.4e-46 156.8 0.0 4e-46 156.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAQ88390.1 - 6.4e-20 71.6 0.0 9.9e-20 71.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAQ88390.1 - 6.6e-06 25.7 0.0 9.7e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 EAQ88390.1 - 0.028 13.9 0.0 0.034 13.6 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_21 PF13304.6 EAQ88390.1 - 0.068 13.0 0.0 0.12 12.2 0.0 1.4 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system PduV-EutP PF10662.9 EAQ88390.1 - 0.2 11.4 0.0 4.2 7.1 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MRP-L28 PF09812.9 EAQ88391.1 - 2.2e-06 27.9 0.0 3.1e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 GATase_5 PF13507.6 EAQ88392.1 - 5e-98 327.3 0.0 8.9e-98 326.5 0.0 1.4 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 EAQ88392.1 - 4.4e-23 82.1 3.8 9.5e-12 45.3 0.4 2.5 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain FGAR-AT_linker PF18072.1 EAQ88392.1 - 9.4e-22 77.3 0.1 2.9e-21 75.7 0.1 1.9 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain FGAR-AT_N PF18076.1 EAQ88392.1 - 0.00096 19.1 0.4 0.0047 16.9 0.3 2.1 1 1 1 2 2 2 1 Formylglycinamide ribonucleotide amidotransferase N-terminal DUF1490 PF07371.12 EAQ88392.1 - 0.15 12.2 0.2 0.44 10.7 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1490) SGTA_dimer PF16546.5 EAQ88393.1 - 4.4e-25 87.2 0.1 7.6e-25 86.5 0.1 1.4 1 0 0 1 1 1 1 Homodimerisation domain of SGTA TPR_1 PF00515.28 EAQ88393.1 - 1.6e-15 56.2 6.9 1.8e-06 27.5 0.2 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 EAQ88393.1 - 9.9e-13 47.2 10.0 0.00012 22.0 0.2 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 EAQ88393.1 - 1.6e-09 38.3 15.3 8.7e-07 29.5 11.5 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 EAQ88393.1 - 8.4e-08 31.8 7.6 0.00033 20.3 1.4 3.3 2 1 1 3 3 3 3 TPR repeat TPR_8 PF13181.6 EAQ88393.1 - 1.8e-06 27.7 3.9 0.053 13.7 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 EAQ88393.1 - 2e-06 27.4 1.7 0.0055 16.6 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 EAQ88393.1 - 2.5e-06 27.5 5.7 0.0013 19.0 0.3 3.8 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 EAQ88393.1 - 3.8e-06 27.3 11.3 0.11 13.4 0.1 3.5 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 EAQ88393.1 - 4.3e-06 27.2 5.6 0.00039 20.9 2.4 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 EAQ88393.1 - 1.7e-05 25.0 6.8 4e-05 23.8 3.7 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat STI1 PF17830.1 EAQ88393.1 - 0.00039 20.3 8.5 0.0019 18.1 6.5 2.3 2 0 0 2 2 2 1 STI1 domain TPR_9 PF13371.6 EAQ88393.1 - 0.0032 17.6 4.6 0.014 15.5 1.7 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 EAQ88393.1 - 0.0085 15.9 9.6 0.056 13.3 1.8 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat XPC-binding PF09280.11 EAQ88393.1 - 0.052 13.3 1.5 0.092 12.5 1.5 1.4 1 0 0 1 1 1 0 XPC-binding domain BTAD PF03704.17 EAQ88393.1 - 0.091 13.2 4.9 4.9 7.6 1.5 2.3 1 1 1 2 2 2 0 Bacterial transcriptional activator domain TPR_6 PF13174.6 EAQ88393.1 - 0.19 12.4 7.0 3.2 8.6 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Spt20 PF12090.8 EAQ88394.1 - 0.012 15.3 7.1 0.018 14.7 7.1 1.1 1 0 0 1 1 1 0 Spt20 family P5-ATPase PF12409.8 EAQ88394.1 - 0.093 12.8 0.0 2.5 8.2 0.0 2.5 2 0 0 2 2 2 0 P5-type ATPase cation transporter RINGv PF12906.7 EAQ88394.1 - 0.1 12.7 6.3 0.18 11.9 6.3 1.4 1 0 0 1 1 1 0 RING-variant domain Roughex PF06020.11 EAQ88394.1 - 0.17 11.0 7.7 0.27 10.3 7.7 1.3 1 0 0 1 1 1 0 Drosophila roughex protein FANCL_C PF11793.8 EAQ88394.1 - 0.23 11.7 4.8 0.39 10.9 4.8 1.3 1 0 0 1 1 1 0 FANCL C-terminal domain DUF1180 PF06679.12 EAQ88394.1 - 0.25 11.7 1.2 0.58 10.5 1.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Pex14_N PF04695.13 EAQ88394.1 - 1.2 9.8 8.8 2.8 8.6 8.8 1.6 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TFIIA PF03153.13 EAQ88395.1 - 0.0075 16.3 2.6 0.0096 16.0 2.6 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.9 EAQ88395.1 - 9.9 4.3 11.2 12 4.1 11.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 GalKase_gal_bdg PF10509.9 EAQ88396.1 - 8.9e-19 66.8 0.0 2.1e-18 65.6 0.0 1.7 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.26 EAQ88396.1 - 2.6e-15 56.4 1.5 2.6e-15 56.4 1.5 2.3 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EAQ88396.1 - 1.7e-11 44.3 0.1 4.2e-11 43.1 0.1 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal TPP_enzyme_C PF02775.21 EAQ88397.1 - 1.7e-50 170.8 1.0 1.6e-49 167.6 0.1 2.6 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_N PF02776.18 EAQ88397.1 - 1.7e-48 164.5 0.9 2.3e-47 160.8 0.3 2.5 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 EAQ88397.1 - 6.4e-41 139.3 1.8 8e-41 139.0 0.4 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain DUF3659 PF12396.8 EAQ88400.1 - 7.5e-16 57.8 3.8 6.7e-11 41.9 1.5 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF3659) Transferase PF02458.15 EAQ88402.1 - 2.2e-16 59.6 0.0 1.4e-12 47.0 0.0 2.3 2 1 0 2 2 2 2 Transferase family SNF2_N PF00176.23 EAQ88403.1 - 6.2e-66 222.5 0.0 9.8e-66 221.8 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-C3HC4_3 PF13920.6 EAQ88403.1 - 7.3e-10 38.6 13.2 1.1e-08 34.8 11.7 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EAQ88403.1 - 8e-10 38.4 14.5 8e-10 38.4 14.5 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EAQ88403.1 - 3.5e-08 33.5 11.7 8.2e-08 32.3 11.7 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 EAQ88403.1 - 1.1e-07 31.7 11.2 3e-07 30.4 11.2 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EAQ88403.1 - 1.2e-07 31.5 15.0 1.2e-07 31.5 15.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EAQ88403.1 - 2.4e-07 31.0 16.6 2.6e-07 30.9 14.3 2.1 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 EAQ88403.1 - 6.1e-07 29.3 12.4 6.1e-07 29.3 12.4 1.8 2 0 0 2 2 1 1 zinc-RING finger domain Helicase_C PF00271.31 EAQ88403.1 - 9.9e-06 25.9 0.1 0.0064 16.8 0.0 2.8 1 1 1 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 EAQ88403.1 - 8.3e-05 22.4 0.0 0.0002 21.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-rbx1 PF12678.7 EAQ88403.1 - 0.0002 21.6 12.1 0.00071 19.8 12.1 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain ResIII PF04851.15 EAQ88403.1 - 0.00024 21.2 0.0 0.00071 19.6 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Prok-RING_4 PF14447.6 EAQ88403.1 - 0.0003 20.6 10.9 0.0003 20.6 10.9 1.9 2 0 0 2 2 1 1 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 EAQ88403.1 - 0.00044 20.3 8.3 0.0012 18.9 8.3 1.7 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-RING_4 PF14570.6 EAQ88403.1 - 0.0041 16.9 8.6 0.011 15.5 8.7 1.7 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain U-box PF04564.15 EAQ88403.1 - 0.0044 17.2 1.3 0.018 15.2 0.1 2.6 2 0 0 2 2 2 1 U-box domain zf-ANAPC11 PF12861.7 EAQ88403.1 - 0.0092 16.0 4.2 0.033 14.2 4.2 2.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Rad50_zn_hook PF04423.14 EAQ88403.1 - 0.013 15.3 0.4 5 7.0 0.0 2.9 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-RING_6 PF14835.6 EAQ88403.1 - 0.047 13.6 4.4 0.12 12.3 4.4 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-Nse PF11789.8 EAQ88403.1 - 0.058 13.2 11.2 0.16 11.9 10.7 1.9 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit HIRAN PF08797.11 EAQ88403.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 HIRAN domain zf-P11 PF03854.14 EAQ88403.1 - 0.13 11.9 8.2 2.7 7.7 3.9 2.6 1 1 1 2 2 2 0 P-11 zinc finger DUF1644 PF07800.12 EAQ88403.1 - 0.97 9.5 7.7 7.6 6.6 0.1 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1644) DZR PF12773.7 EAQ88403.1 - 2.5 8.2 6.1 6.9 6.8 6.1 1.7 1 1 0 1 1 1 0 Double zinc ribbon Preseq_ALAS PF09029.10 EAQ88403.1 - 3.5 8.1 6.9 2.9 8.4 1.5 3.3 3 1 0 3 3 2 0 5-aminolevulinate synthase presequence CSTF_C PF14304.6 EAQ88403.1 - 7 6.3 7.9 9.6 5.9 0.8 2.6 2 0 0 2 2 2 0 Transcription termination and cleavage factor C-terminal NmrA PF05368.13 EAQ88404.1 - 5.4e-11 42.5 0.0 8.9e-11 41.8 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EAQ88404.1 - 0.095 12.6 0.3 1.3 8.9 0.3 2.4 1 1 0 1 1 1 0 NAD(P)H-binding DUF3748 PF12566.8 EAQ88404.1 - 0.15 12.0 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3748) Glyco_hydro_61 PF03443.14 EAQ88405.1 - 1.2e-50 172.4 0.0 1.4e-50 172.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Cpn10 PF00166.21 EAQ88406.1 - 1.1e-29 102.4 0.0 1.2e-29 102.2 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Pkinase PF00069.25 EAQ88407.1 - 7.7e-48 163.2 0.0 2.3e-47 161.6 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ88407.1 - 1.7e-21 76.7 0.0 3.8e-21 75.5 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 EAQ88407.1 - 0.0047 16.9 0.0 0.0092 15.9 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EAQ88407.1 - 0.056 12.4 0.0 0.056 12.4 0.0 1.4 2 0 0 2 2 2 0 Haspin like kinase domain Ribosomal_L11 PF00298.19 EAQ88408.1 - 5e-27 94.2 0.9 7.5e-27 93.7 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.14 EAQ88408.1 - 1.4e-25 88.9 0.2 2.4e-25 88.1 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Svf1_C PF17187.4 EAQ88409.1 - 6.9e-63 211.4 0.6 1.4e-62 210.4 0.1 1.8 3 0 0 3 3 3 1 Svf1-like C-terminal lipocalin-like domain Svf1 PF08622.10 EAQ88409.1 - 3.1e-57 193.2 0.1 4.3e-57 192.7 0.1 1.2 1 0 0 1 1 1 1 Svf1-like N-terminal lipocalin domain CENP-T_C PF15511.6 EAQ88410.1 - 0.00036 20.6 0.1 0.00075 19.6 0.1 1.4 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 EAQ88410.1 - 0.027 14.7 1.6 0.067 13.5 0.1 2.0 1 1 1 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PCP_red PF08369.10 EAQ88410.1 - 0.043 14.0 1.4 0.11 12.8 0.2 2.1 2 0 0 2 2 2 0 Proto-chlorophyllide reductase 57 kD subunit Acetyltransf_1 PF00583.25 EAQ88411.1 - 2.9e-05 24.3 0.1 5e-05 23.5 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family DUF2955 PF11168.8 EAQ88411.1 - 0.022 14.6 0.2 0.03 14.2 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2955) Pho86 PF11124.8 EAQ88411.1 - 0.034 13.6 0.1 0.048 13.1 0.1 1.2 1 0 0 1 1 1 0 Inorganic phosphate transporter Pho86 Acetyltransf_CG PF14542.6 EAQ88411.1 - 0.21 11.8 0.0 0.4 10.8 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase DDE_1 PF03184.19 EAQ88412.1 - 1.9e-27 96.1 0.0 3.1e-27 95.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.16 EAQ88412.1 - 2.8e-09 36.6 0.0 6.9e-09 35.3 0.0 1.7 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.16 EAQ88412.1 - 2.2e-08 34.0 0.1 1.6e-07 31.2 0.0 2.2 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.6 EAQ88412.1 - 6.1e-05 22.8 0.1 0.019 14.7 0.0 3.1 3 0 0 3 3 3 1 DDE superfamily endonuclease SpoIIID PF12116.8 EAQ88412.1 - 0.051 13.7 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Stage III sporulation protein D ZapB PF06005.12 EAQ88412.1 - 0.11 13.0 1.3 0.67 10.4 1.0 2.7 2 0 0 2 2 2 0 Cell division protein ZapB AOX PF01786.17 EAQ88413.1 - 4e-90 301.1 0.1 4.8e-90 300.9 0.1 1.1 1 0 0 1 1 1 1 Alternative oxidase zf-C2H2 PF00096.26 EAQ88414.1 - 1.6e-12 47.1 12.2 4.9e-06 26.7 2.4 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EAQ88414.1 - 3.4e-12 46.2 9.1 2.6e-07 30.8 0.2 3.8 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_6 PF13912.6 EAQ88414.1 - 5.5e-06 26.2 12.4 0.00044 20.2 0.3 4.2 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EAQ88414.1 - 6.8e-06 26.2 0.4 0.12 12.7 0.1 3.6 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EAQ88414.1 - 0.00014 22.2 1.5 0.018 15.4 0.2 3.0 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 EAQ88414.1 - 0.00015 22.3 23.5 0.00056 20.5 1.5 4.5 5 0 0 5 5 3 3 C2H2-type zinc finger TOH_N PF12549.8 EAQ88414.1 - 0.012 15.4 0.2 0.17 11.8 0.0 2.9 2 0 0 2 2 2 0 Tyrosine hydroxylase N terminal zf-C2H2_11 PF16622.5 EAQ88414.1 - 0.015 15.1 4.8 0.56 10.0 0.7 3.2 3 0 0 3 3 3 0 zinc-finger C2H2-type Zn_ribbon_recom PF13408.6 EAQ88414.1 - 0.064 13.8 1.3 0.13 12.8 1.3 1.5 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain zf-Di19 PF05605.12 EAQ88414.1 - 0.73 10.2 5.6 0.25 11.7 1.4 2.2 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding LIM PF00412.22 EAQ88414.1 - 1.4 9.2 3.4 19 5.6 1.5 2.3 1 1 1 2 2 2 0 LIM domain C5HCH PF17982.1 EAQ88414.1 - 7.2 6.9 6.0 42 4.4 1.3 2.6 1 1 1 2 2 2 0 NSD Cys-His rich domain ADH_zinc_N PF00107.26 EAQ88415.1 - 2.5e-07 30.7 0.0 4.4e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EAQ88415.1 - 0.00013 21.8 0.0 0.00026 20.8 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain DHDPS PF00701.22 EAQ88416.1 - 0.03 13.0 0.0 0.047 12.4 0.0 1.2 1 0 0 1 1 1 0 Dihydrodipicolinate synthetase family Trypan_PARP PF05887.11 EAQ88417.1 - 0.00034 20.6 50.0 0.00034 20.6 50.0 20.1 6 4 15 21 21 21 6 Procyclic acidic repetitive protein (PARP) MFS_1 PF07690.16 EAQ88418.1 - 1.8e-47 162.0 22.0 2.6e-47 161.5 22.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EAQ88418.1 - 1.1e-09 37.6 10.1 1.1e-09 37.6 10.1 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 EAQ88418.1 - 7.9e-06 24.6 5.3 1.1e-05 24.1 5.3 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Syntaxin-18_N PF10496.9 EAQ88419.1 - 9.5e-08 32.2 1.5 1.5e-06 28.3 0.1 3.0 2 1 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus MIF4G_like_2 PF09090.11 EAQ88419.1 - 0.068 12.6 3.1 0.32 10.4 0.3 2.5 1 1 0 2 2 2 0 MIF4G like DUF3071 PF11268.8 EAQ88419.1 - 0.6 10.2 6.6 0.083 12.9 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3071) DAGK_cat PF00781.24 EAQ88420.1 - 3.6e-23 81.6 0.0 5.4e-23 81.0 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Nop52 PF05997.12 EAQ88421.1 - 3.1e-49 167.7 0.1 3.9e-49 167.4 0.1 1.0 1 0 0 1 1 1 1 Nucleolar protein,Nop52 Aminotran_1_2 PF00155.21 EAQ88422.1 - 1.8e-55 188.6 0.0 2.2e-35 122.5 0.0 2.0 1 1 1 2 2 2 2 Aminotransferase class I and II NARP1 PF12569.8 EAQ88423.1 - 4.2e-180 600.1 20.7 1.7e-149 499.0 6.2 3.3 2 1 1 3 3 3 3 NMDA receptor-regulated protein 1 TPR_16 PF13432.6 EAQ88423.1 - 2.3e-19 69.7 31.3 0.00093 19.8 7.2 8.7 8 3 2 10 10 9 4 Tetratricopeptide repeat TPR_19 PF14559.6 EAQ88423.1 - 1.9e-18 66.7 29.3 4e-05 24.0 0.1 7.2 7 0 0 7 7 6 6 Tetratricopeptide repeat TPR_14 PF13428.6 EAQ88423.1 - 8e-17 60.5 27.2 0.00063 20.3 0.0 11.1 7 4 5 12 12 10 4 Tetratricopeptide repeat TPR_2 PF07719.17 EAQ88423.1 - 8.9e-16 56.7 41.8 0.00058 19.8 0.1 11.6 11 1 1 12 12 12 4 Tetratricopeptide repeat TPR_9 PF13371.6 EAQ88423.1 - 1.2e-14 54.2 12.1 0.0015 18.6 0.0 7.7 5 3 2 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.6 EAQ88423.1 - 6.1e-13 48.2 12.7 0.00055 20.1 0.0 8.3 10 0 0 10 10 8 3 Tetratricopeptide repeat TPR_11 PF13414.6 EAQ88423.1 - 4.9e-11 42.1 7.8 0.0004 20.0 0.0 6.6 6 1 0 6 6 6 2 TPR repeat TPR_1 PF00515.28 EAQ88423.1 - 8.2e-10 38.1 33.8 2e-05 24.2 0.1 10.0 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_8 PF13181.6 EAQ88423.1 - 2.4e-09 36.7 25.1 0.003 17.6 0.0 10.2 11 0 0 11 11 9 3 Tetratricopeptide repeat TPR_12 PF13424.6 EAQ88423.1 - 2.4e-09 37.3 19.6 0.32 11.3 0.0 7.7 8 1 0 8 8 7 3 Tetratricopeptide repeat ANAPC3 PF12895.7 EAQ88423.1 - 6.5e-07 29.5 21.1 0.0043 17.2 0.7 5.2 4 1 1 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.6 EAQ88423.1 - 9.6e-06 25.6 6.5 2.3 8.3 0.1 5.7 6 0 0 6 6 5 2 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 EAQ88423.1 - 0.0025 17.6 15.8 2.8 7.9 0.1 7.2 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_4 PF07721.14 EAQ88423.1 - 0.0073 16.8 14.2 7 7.6 0.0 6.8 7 0 0 7 7 6 1 Tetratricopeptide repeat PPTA PF01239.22 EAQ88423.1 - 0.0082 15.8 0.5 2.2 8.1 0.0 3.7 3 0 0 3 3 3 1 Protein prenyltransferase alpha subunit repeat YcaO_C PF18381.1 EAQ88423.1 - 0.0083 16.1 1.0 0.039 13.9 0.1 2.5 2 1 1 3 3 3 1 YcaO cyclodehydratase C-terminal domain TPR_3 PF07720.12 EAQ88423.1 - 0.016 15.2 7.5 1.1 9.3 0.1 3.6 4 0 0 4 4 3 0 Tetratricopeptide repeat BTAD PF03704.17 EAQ88423.1 - 0.016 15.6 4.1 0.016 15.6 4.1 3.3 4 1 1 5 5 3 0 Bacterial transcriptional activator domain HrpB1_HrpK PF09613.10 EAQ88423.1 - 0.034 13.8 0.4 4.6 6.9 0.0 3.7 4 0 0 4 4 4 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_7 PF13176.6 EAQ88423.1 - 0.037 14.0 19.0 76 3.7 2.5 8.5 9 1 0 9 9 7 0 Tetratricopeptide repeat RNA_pol_Rpc4 PF05132.14 EAQ88423.1 - 1.4 9.4 4.7 2.9 8.3 4.7 1.5 1 0 0 1 1 1 0 RNA polymerase III RPC4 Zn_clus PF00172.18 EAQ88424.1 - 0.049 13.8 3.7 0.086 13.0 3.7 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Comm PF15957.5 EAQ88424.1 - 0.55 10.6 2.7 1.2 9.5 2.7 1.5 1 0 0 1 1 1 0 Commissureless 2-Hacid_dh_C PF02826.19 EAQ88425.1 - 9.2e-57 191.3 0.0 1.2e-56 190.9 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EAQ88425.1 - 2.9e-17 62.6 0.0 6.1e-17 61.5 0.0 1.4 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EAQ88425.1 - 5.8e-06 26.6 0.1 9.4e-06 25.9 0.1 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 EAQ88425.1 - 0.0022 17.6 0.1 0.0034 17.0 0.1 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain AlaDh_PNT_C PF01262.21 EAQ88425.1 - 0.02 14.2 0.3 0.051 12.9 0.3 1.7 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain AdoHcyase_NAD PF00670.21 EAQ88425.1 - 0.022 14.8 0.0 0.089 12.9 0.0 1.9 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain AdoHcyase PF05221.17 EAQ88426.1 - 5.1e-132 439.5 0.0 9.1e-75 251.6 0.1 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 EAQ88426.1 - 7.5e-82 273.2 2.9 1.2e-81 272.6 2.9 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 EAQ88426.1 - 1.5e-05 24.5 0.1 3.6e-05 23.2 0.1 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 EAQ88426.1 - 0.00059 19.4 0.3 0.0011 18.5 0.3 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain ELFV_dehydrog PF00208.21 EAQ88426.1 - 0.03 14.0 0.4 0.065 12.9 0.4 1.6 1 1 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase TrkA_N PF02254.18 EAQ88426.1 - 0.096 13.0 0.1 0.2 11.9 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain JAB PF01398.21 EAQ88427.1 - 6.3e-05 22.9 0.4 0.0019 18.2 0.4 2.5 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Glycogen_syn PF05693.13 EAQ88428.1 - 0.034 12.7 0.0 0.041 12.4 0.0 1.2 1 0 0 1 1 1 0 Glycogen synthase TMEM210 PF15195.6 EAQ88428.1 - 0.11 12.9 0.0 0.17 12.3 0.0 1.2 1 0 0 1 1 1 0 TMEM210 family Mito_carr PF00153.27 EAQ88429.1 - 3.6e-44 148.6 2.5 5.3e-17 61.5 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Helo_like_N PF17111.5 EAQ88430.1 - 0.00042 19.8 0.3 0.00042 19.8 0.3 1.8 2 0 0 2 2 2 1 Fungal N-terminal domain of STAND proteins TPR_12 PF13424.6 EAQ88430.1 - 0.0083 16.4 4.4 0.74 10.1 0.0 3.8 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 EAQ88430.1 - 0.018 15.1 3.0 26 5.2 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 EAQ88430.1 - 0.095 13.6 2.8 14 6.9 0.1 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 EAQ88430.1 - 0.17 11.8 1.8 2.1 8.3 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat VHP PF02209.19 EAQ88430.1 - 0.18 11.9 0.1 0.5 10.5 0.1 1.8 1 0 0 1 1 1 0 Villin headpiece domain MFS_1 PF07690.16 EAQ88431.1 - 3.1e-18 65.8 29.1 7.3e-16 58.0 18.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.18 EAQ88432.1 - 9.5e-20 70.7 0.0 1.5e-19 70.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Tyrosinase PF00264.20 EAQ88433.1 - 7.2e-45 154.0 0.0 1.1e-44 153.4 0.0 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase MFS_1 PF07690.16 EAQ88436.1 - 6.1e-23 81.3 30.9 7.3e-22 77.8 13.2 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EAQ88436.1 - 1.2 7.6 13.7 0.0055 15.3 3.0 2.2 3 0 0 3 3 3 0 MFS/sugar transport protein Mucin PF01456.17 EAQ88437.1 - 0.0039 17.2 15.8 0.0066 16.4 15.8 1.3 1 0 0 1 1 1 1 Mucin-like glycoprotein zf-RVT PF13966.6 EAQ88437.1 - 0.024 15.3 0.0 0.094 13.4 0.0 1.9 2 0 0 2 2 2 0 zinc-binding in reverse transcriptase BSP_II PF05432.11 EAQ88437.1 - 1.2 8.8 11.3 2.1 8.0 11.3 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) FAM199X PF15814.5 EAQ88437.1 - 3.2 6.7 9.9 5.3 6.0 9.9 1.2 1 0 0 1 1 1 0 Protein family FAM199X RVT_1 PF00078.27 EAQ88438.1 - 4.4e-29 101.6 0.0 6.9e-29 100.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 EAQ88438.1 - 5.8e-14 51.9 0.0 1.3e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 EAQ88438.1 - 2.6e-13 49.8 0.5 7e-13 48.5 0.1 1.9 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 EAQ88438.1 - 1.4e-10 41.4 0.0 5.3e-10 39.5 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain RT_RNaseH PF17917.1 EAQ88438.1 - 7.1e-10 39.1 0.4 7.3e-06 26.2 0.2 2.5 1 1 1 2 2 2 2 RNase H-like domain found in reverse transcriptase Gag_p24 PF00607.20 EAQ88438.1 - 0.01 15.7 0.2 0.096 12.5 0.0 2.3 2 1 0 2 2 2 0 gag gene protein p24 (core nucleocapsid protein) Chromo PF00385.24 EAQ88438.1 - 0.013 15.4 0.0 0.035 14.0 0.0 1.8 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 EAQ88438.1 - 0.027 14.7 0.0 0.07 13.4 0.0 1.8 1 0 0 1 1 1 0 H2C2 zinc finger UvrD_C_2 PF13538.6 EAQ88440.1 - 0.00026 20.8 0.0 0.00054 19.7 0.0 1.5 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.14 EAQ88440.1 - 0.00047 18.2 0.0 0.00055 18.0 0.0 1.0 1 0 0 1 1 1 1 Helicase HTH_Tnp_Tc5 PF03221.16 EAQ88443.1 - 1.7e-14 53.5 0.0 4.2e-14 52.3 0.0 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.16 EAQ88443.1 - 2.4e-13 49.6 0.0 6.3e-13 48.2 0.0 1.7 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_23 PF13384.6 EAQ88443.1 - 0.0012 18.6 0.0 0.0033 17.2 0.0 1.8 1 0 0 1 1 1 1 Homeodomain-like domain Sigma70_r4_2 PF08281.12 EAQ88443.1 - 0.011 15.4 0.1 0.046 13.4 0.0 2.1 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_AsnC-type PF13404.6 EAQ88443.1 - 0.031 14.1 0.0 0.087 12.7 0.0 1.7 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain TnsD PF15978.5 EAQ88443.1 - 0.039 12.9 0.2 0.069 12.1 0.1 1.4 1 1 0 1 1 1 0 Tn7-like transposition protein D HTH_28 PF13518.6 EAQ88443.1 - 0.065 13.4 0.0 0.19 11.9 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain MULE PF10551.9 EAQ88444.1 - 6.4e-25 87.4 0.4 1.6e-24 86.2 0.4 1.7 1 0 0 1 1 1 1 MULE transposase domain zf-CCHC_6 PF15288.6 EAQ88444.1 - 0.00063 19.5 0.4 0.0015 18.3 0.4 1.7 1 0 0 1 1 1 1 Zinc knuckle PRIMA1 PF16101.5 EAQ88444.1 - 2.6 8.1 5.7 5.2 7.1 5.7 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 DDE_1 PF03184.19 EAQ88445.1 - 4.2e-27 94.9 0.0 7.7e-27 94.0 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.16 EAQ88445.1 - 9.7e-11 41.2 0.0 2.5e-10 39.9 0.0 1.8 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.16 EAQ88445.1 - 2.2e-08 34.0 0.1 1.6e-07 31.2 0.0 2.2 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain SpoIIID PF12116.8 EAQ88445.1 - 0.026 14.6 0.0 0.06 13.4 0.0 1.5 1 0 0 1 1 1 0 Stage III sporulation protein D HTH_23 PF13384.6 EAQ88445.1 - 0.061 13.1 0.1 0.33 10.8 0.0 2.3 2 0 0 2 2 2 0 Homeodomain-like domain ZapB PF06005.12 EAQ88445.1 - 0.086 13.3 1.2 0.56 10.7 1.2 2.5 1 0 0 1 1 1 0 Cell division protein ZapB DDE_1 PF03184.19 EAQ88446.1 - 2.5e-19 69.6 0.0 4.4e-19 68.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease zf-RVT PF13966.6 EAQ88446.1 - 0.0097 16.6 2.0 0.11 13.2 0.0 2.5 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase HTH_psq PF05225.16 EAQ88446.1 - 0.01 15.6 0.0 0.021 14.5 0.0 1.6 1 0 0 1 1 1 0 helix-turn-helix, Psq domain ZapB PF06005.12 EAQ88446.1 - 0.09 13.2 1.1 0.24 11.9 1.1 1.7 1 0 0 1 1 1 0 Cell division protein ZapB RVT_1 PF00078.27 EAQ88449.1 - 7.1e-29 100.9 0.0 1.3e-28 100.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 EAQ88449.1 - 8.8e-13 48.2 1.4 1.7e-12 47.2 0.0 2.2 2 0 0 2 2 2 1 Integrase zinc binding domain Chromo PF00385.24 EAQ88449.1 - 7.1e-12 45.0 0.0 2.6e-11 43.3 0.0 2.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 EAQ88449.1 - 8.8e-11 42.0 0.0 2.3e-10 40.7 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 EAQ88449.1 - 6.4e-07 29.6 0.1 2.6e-06 27.7 0.1 2.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 EAQ88449.1 - 2.8e-05 24.1 0.0 9.8e-05 22.3 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase HAP1_N PF04849.13 EAQ88449.1 - 6e-05 22.4 1.9 0.00017 20.9 1.9 1.7 1 0 0 1 1 1 1 HAP1 N-terminal conserved region DUF4939 PF16297.5 EAQ88449.1 - 0.00011 22.1 0.0 0.00075 19.4 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4939) zf-CCHC PF00098.23 EAQ88449.1 - 0.0012 18.9 3.9 0.0027 17.7 3.9 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-H2C2 PF09337.10 EAQ88449.1 - 0.0018 18.4 0.3 0.0068 16.6 0.0 2.2 2 0 0 2 2 2 1 H2C2 zinc finger zf-CCHC_5 PF14787.6 EAQ88449.1 - 0.054 13.2 3.4 0.18 11.6 3.4 1.8 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger Laminin_II PF06009.12 EAQ88449.1 - 1.1 9.3 4.6 12 5.9 0.3 2.9 2 0 0 2 2 2 0 Laminin Domain II Retrotrans_gag PF03732.17 EAQ88449.1 - 4.1 7.7 10.9 0.097 13.0 0.3 3.6 4 0 0 4 4 4 0 Retrotransposon gag protein ZapB PF06005.12 EAQ88449.1 - 5.3 7.6 9.8 4.5 7.8 5.6 3.3 2 0 0 2 2 2 0 Cell division protein ZapB IFT57 PF10498.9 EAQ88449.1 - 6.2 5.7 14.7 0.35 9.8 6.3 2.8 3 0 0 3 3 3 0 Intra-flagellar transport protein 57 TauD PF02668.16 EAQ88450.1 - 2.3e-38 132.5 0.1 8.7e-35 120.8 0.0 2.0 2 0 0 2 2 2 2 Taurine catabolism dioxygenase TauD, TfdA family UL16 PF17622.2 EAQ88450.1 - 0.042 13.5 0.0 0.067 12.8 0.0 1.3 1 0 0 1 1 1 0 Viral unique long protein 16 MFS_1 PF07690.16 EAQ88451.1 - 1.1e-08 34.5 6.6 1.1e-08 34.5 6.6 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Rib_5-P_isom_A PF06026.14 EAQ88452.1 - 2.4e-47 160.7 0.0 3.5e-47 160.2 0.0 1.2 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.22 EAQ88452.1 - 0.046 13.6 0.0 4.9 7.1 0.0 2.2 2 0 0 2 2 2 0 DeoR C terminal sensor domain Fungal_trans PF04082.18 EAQ88454.1 - 6e-11 41.9 0.0 9.9e-11 41.2 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EAQ88454.1 - 1.5e-05 25.0 7.7 2.7e-05 24.2 7.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ion_trans PF00520.31 EAQ88455.1 - 1.1e-05 24.8 21.3 6.1e-05 22.4 21.3 2.0 1 1 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 EAQ88455.1 - 8e-05 21.5 17.9 0.0023 16.7 17.9 2.2 1 1 0 1 1 1 1 Polycystin cation channel UPF0542 PF15086.6 EAQ88455.1 - 0.0075 16.2 0.3 0.032 14.2 0.0 2.2 2 0 0 2 2 2 1 Uncharacterised protein family UPF0542 TSC22 PF01166.18 EAQ88455.1 - 0.1 12.9 1.9 0.27 11.6 1.9 1.7 1 0 0 1 1 1 0 TSC-22/dip/bun family AAA PF00004.29 EAQ88456.1 - 4e-15 56.4 0.1 1.3e-14 54.8 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EAQ88456.1 - 0.0053 17.0 1.7 0.12 12.6 0.1 2.7 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 EAQ88456.1 - 0.014 15.4 0.0 0.032 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 EAQ88456.1 - 0.058 13.9 0.1 0.41 11.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EAQ88456.1 - 0.54 10.6 4.4 0.26 11.6 0.5 2.5 2 1 0 2 2 2 0 AAA ATPase domain Med30 PF11315.8 EAQ88456.1 - 3.9 7.7 8.3 0.17 12.1 1.5 2.2 3 0 0 3 3 3 0 Mediator complex subunit 30 Methyltransf_10 PF05971.12 EAQ88458.1 - 4.1e-39 134.7 0.2 3.4e-19 69.3 0.0 3.1 1 1 2 3 3 3 3 RNA methyltransferase XAP5 PF04921.14 EAQ88459.1 - 1e-95 320.3 0.0 2.2e-95 319.2 0.0 1.5 1 1 1 2 2 2 1 XAP5, circadian clock regulator DUF4604 PF15377.6 EAQ88459.1 - 0.006 17.0 3.0 0.006 17.0 3.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4604) UvrD_C_2 PF13538.6 EAQ88462.1 - 0.00026 20.8 0.0 0.00054 19.7 0.0 1.5 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.14 EAQ88462.1 - 0.00047 18.2 0.0 0.00055 18.0 0.0 1.0 1 0 0 1 1 1 1 Helicase Dynamin_N PF00350.23 EAQ88463.1 - 5.5e-35 120.9 0.0 1.1e-34 119.9 0.0 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 EAQ88463.1 - 1.6e-29 103.0 0.0 2.8e-29 102.2 0.0 1.4 1 0 0 1 1 1 1 Dynamin central region Med9 PF07544.13 EAQ88463.1 - 6.6e-06 26.1 1.8 0.0003 20.8 0.2 3.2 3 0 0 3 3 3 1 RNA polymerase II transcription mediator complex subunit 9 MMR_HSR1 PF01926.23 EAQ88463.1 - 0.00055 20.0 0.1 0.013 15.6 0.1 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase IreB PF06135.12 EAQ88463.1 - 0.024 14.8 0.0 0.097 12.9 0.0 2.1 2 0 0 2 2 2 0 IreB regulatory phosphoprotein GED PF02212.18 EAQ88463.1 - 0.026 14.7 0.2 0.65 10.2 0.0 3.1 3 0 0 3 3 3 0 Dynamin GTPase effector domain AAA_15 PF13175.6 EAQ88463.1 - 0.069 12.8 0.1 0.16 11.7 0.1 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 EAQ88463.1 - 0.18 11.6 0.0 0.39 10.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain TINF2_N PF14973.6 EAQ88463.1 - 0.18 12.1 1.2 3.5 8.0 0.1 3.2 3 1 0 3 3 3 0 TERF1-interacting nuclear factor 2 N-terminus DUF3232 PF11554.8 EAQ88463.1 - 0.19 12.1 0.5 0.71 10.3 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3232) THOC7 PF05615.13 EAQ88463.1 - 0.29 11.4 4.0 6 7.2 0.1 2.9 3 0 0 3 3 3 0 Tho complex subunit 7 RVT_1 PF00078.27 EAQ88464.1 - 3.5e-13 49.6 0.0 1e-12 48.0 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Latarcin PF10279.9 EAQ88464.1 - 0.0086 16.5 0.0 2.3 8.7 0.0 3.3 2 2 0 2 2 2 1 Latarcin precursor DASH_Ask1 PF08655.10 EAQ88464.1 - 0.072 13.0 0.0 0.22 11.4 0.0 1.8 1 0 0 1 1 1 0 DASH complex subunit Ask1 TcdA_TcdB PF12919.7 EAQ88464.1 - 0.09 12.1 0.7 0.14 11.4 0.7 1.2 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain DUF812 PF05667.11 EAQ88464.1 - 0.16 10.8 7.0 0.28 10.0 7.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF3450 PF11932.8 EAQ88464.1 - 0.76 9.0 11.0 38 3.5 11.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3450) Radial_spoke_3 PF06098.11 EAQ88464.1 - 5.8 6.1 12.7 9.5 5.4 12.7 1.3 1 0 0 1 1 1 0 Radial spoke protein 3 NAD_binding_4 PF07993.12 EAQ88465.1 - 0.001 18.3 0.0 0.0043 16.2 0.0 1.9 2 0 0 2 2 2 1 Male sterility protein Epimerase PF01370.21 EAQ88465.1 - 0.058 12.8 0.0 0.078 12.4 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DapB_N PF01113.20 EAQ88465.1 - 0.1 12.7 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus GMC_oxred_C PF05199.13 EAQ88466.1 - 1.9e-32 112.8 0.0 3.1e-32 112.1 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 EAQ88466.1 - 2.8e-29 102.4 0.0 6.5e-27 94.7 0.0 2.8 2 1 0 2 2 2 1 GMC oxidoreductase NAD_binding_8 PF13450.6 EAQ88466.1 - 0.00057 20.1 0.1 0.0024 18.0 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EAQ88466.1 - 0.0016 17.7 0.0 0.0028 16.9 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EAQ88466.1 - 0.029 13.5 0.2 0.071 12.2 0.2 1.6 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 EAQ88466.1 - 0.12 11.4 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein PhoPQ_related PF10142.9 EAQ88466.1 - 0.12 11.0 0.0 0.2 10.3 0.0 1.2 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein Pyr_redox_3 PF13738.6 EAQ88466.1 - 0.24 10.6 0.0 22 4.2 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Dimer_Tnp_hAT PF05699.14 EAQ88467.1 - 4.3e-21 74.5 1.5 9.6e-21 73.4 1.5 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF378 PF04070.12 EAQ88468.1 - 0.017 15.0 4.3 0.052 13.4 4.3 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF378) DUF751 PF05421.11 EAQ88468.1 - 0.044 14.5 4.1 0.044 14.5 4.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF751) COX8 PF02285.15 EAQ88468.1 - 0.28 11.1 0.1 0.28 11.1 0.1 3.7 6 0 0 6 6 6 0 Cytochrome oxidase c subunit VIII DctQ PF04290.12 EAQ88468.1 - 6.2 6.8 21.6 0.067 13.1 8.7 3.2 1 1 2 3 3 3 0 Tripartite ATP-independent periplasmic transporters, DctQ component ADH_zinc_N_2 PF13602.6 EAQ88469.1 - 1.4e-28 100.6 0.0 1.9e-28 100.2 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EAQ88469.1 - 4.4e-18 65.5 0.0 6.9e-18 64.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PALP PF00291.25 EAQ88469.1 - 0.0042 16.6 0.2 0.0095 15.4 0.1 1.6 1 1 1 2 2 2 1 Pyridoxal-phosphate dependent enzyme YjeF_N PF03853.15 EAQ88469.1 - 0.027 14.4 0.3 0.063 13.2 0.2 1.6 2 0 0 2 2 2 0 YjeF-related protein N-terminus Esterase_phd PF10503.9 EAQ88471.1 - 1.8e-24 86.5 1.5 2.3e-24 86.1 1.5 1.1 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 EAQ88471.1 - 1.6e-08 34.3 1.8 2.4e-08 33.7 1.8 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 EAQ88471.1 - 0.00031 20.5 0.7 0.00049 19.8 0.7 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.16 EAQ88471.1 - 0.013 15.3 0.5 0.028 14.2 0.2 1.6 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase COesterase PF00135.28 EAQ88471.1 - 0.02 13.8 4.6 0.059 12.2 1.4 2.0 2 0 0 2 2 2 0 Carboxylesterase family Abhydrolase_3 PF07859.13 EAQ88471.1 - 0.021 14.7 0.4 0.058 13.2 0.4 2.0 1 1 0 1 1 1 0 alpha/beta hydrolase fold LIP PF03583.14 EAQ88471.1 - 0.045 13.1 2.4 5.5 6.2 1.8 2.2 2 0 0 2 2 2 0 Secretory lipase BAAT_C PF08840.11 EAQ88471.1 - 0.11 12.4 0.4 0.28 11.1 0.5 1.8 2 1 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.18 EAQ88471.1 - 0.26 10.8 2.0 0.74 9.3 2.0 1.9 1 1 0 1 1 1 0 Dienelactone hydrolase family AOX PF01786.17 EAQ88474.1 - 5.9e-73 245.0 0.0 7.5e-73 244.7 0.0 1.1 1 0 0 1 1 1 1 Alternative oxidase Astro_capsid_N PF03115.14 EAQ88475.1 - 0.17 10.5 4.0 0.27 9.8 4.0 1.2 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Alpha_GJ PF03229.13 EAQ88475.1 - 2.6 8.6 7.2 4.3 7.9 7.2 1.3 1 0 0 1 1 1 0 Alphavirus glycoprotein J RVT_1 PF00078.27 EAQ88476.1 - 2.2e-31 109.1 0.0 1.1e-30 106.9 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 EAQ88476.1 - 1.8e-25 89.1 0.0 5.2e-25 87.6 0.0 1.9 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 EAQ88476.1 - 0.00023 20.7 0.2 0.00054 19.6 0.2 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-CCHC PF00098.23 EAQ88476.1 - 0.0029 17.6 1.7 0.0029 17.6 1.7 2.7 2 0 0 2 2 1 1 Zinc knuckle SlyX PF04102.12 EAQ88476.1 - 0.0073 16.9 5.7 0.091 13.4 5.7 2.9 1 1 0 1 1 1 1 SlyX USP8_interact PF08941.10 EAQ88476.1 - 0.076 12.8 0.1 0.22 11.3 0.1 1.8 1 0 0 1 1 1 0 USP8 interacting CorA PF01544.18 EAQ88476.1 - 0.08 12.2 1.5 0.18 11.1 1.5 1.5 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein CENP-F_leu_zip PF10473.9 EAQ88476.1 - 0.093 12.8 0.8 0.26 11.3 0.8 1.8 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HMMR_N PF15905.5 EAQ88476.1 - 0.096 12.1 0.4 0.16 11.4 0.4 1.2 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal PKcGMP_CC PF16808.5 EAQ88476.1 - 0.15 11.9 0.8 0.53 10.2 0.8 2.0 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF3584 PF12128.8 EAQ88476.1 - 0.34 8.4 4.6 0.53 7.7 4.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) YlqD PF11068.8 EAQ88476.1 - 0.88 10.0 3.6 3.1 8.2 3.6 1.9 1 0 0 1 1 1 0 YlqD protein Exonuc_VII_L PF02601.15 EAQ88476.1 - 9.8 5.6 8.5 1.9 8.0 4.5 1.8 2 0 0 2 2 2 0 Exonuclease VII, large subunit DUF4419 PF14388.6 EAQ88477.1 - 1.6e-98 329.9 0.0 1.9e-98 329.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) HMMR_N PF15905.5 EAQ88478.1 - 6.1e-06 25.9 22.9 6.1e-06 25.9 22.9 2.3 2 0 0 2 2 1 1 Hyaluronan mediated motility receptor N-terminal Spc7 PF08317.11 EAQ88478.1 - 0.00018 20.5 25.1 0.00018 20.5 25.1 3.2 1 1 2 3 3 3 1 Spc7 kinetochore protein Atg14 PF10186.9 EAQ88478.1 - 0.00091 18.4 10.9 0.00091 18.4 10.9 2.4 1 1 0 2 2 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Myosin_tail_1 PF01576.19 EAQ88478.1 - 0.001 17.0 54.9 0.0015 16.4 54.9 1.1 1 0 0 1 1 1 1 Myosin tail GAS PF13851.6 EAQ88478.1 - 0.0022 17.4 18.4 0.0022 17.4 18.4 3.2 1 1 2 3 3 3 1 Growth-arrest specific micro-tubule binding ATG16 PF08614.11 EAQ88478.1 - 0.0045 17.2 17.9 0.0045 17.2 17.9 3.8 1 1 2 3 3 3 1 Autophagy protein 16 (ATG16) Fib_alpha PF08702.10 EAQ88478.1 - 0.0045 17.2 10.5 0.0045 17.2 10.5 4.5 2 1 4 6 6 6 2 Fibrinogen alpha/beta chain family CENP-F_leu_zip PF10473.9 EAQ88478.1 - 0.0046 17.0 13.4 0.0046 17.0 13.4 4.4 1 1 3 4 4 4 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SlyX PF04102.12 EAQ88478.1 - 0.0082 16.7 7.5 0.0082 16.7 7.5 5.1 2 2 1 4 4 3 2 SlyX PKcGMP_CC PF16808.5 EAQ88478.1 - 0.035 13.9 0.4 0.035 13.9 0.4 4.4 4 1 1 5 5 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF3584 PF12128.8 EAQ88478.1 - 0.2 9.1 52.3 0.053 11.0 43.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Troponin PF00992.20 EAQ88478.1 - 0.95 9.8 49.5 2 8.7 4.2 5.4 1 1 4 5 5 5 0 Troponin HAP1_N PF04849.13 EAQ88478.1 - 1 8.5 51.4 19 4.4 9.8 3.2 1 1 1 2 2 2 0 HAP1 N-terminal conserved region Tropomyosin_1 PF12718.7 EAQ88478.1 - 1.3 9.2 68.6 0.032 14.4 18.5 4.7 1 1 3 4 4 3 0 Tropomyosin like RasGAP_C PF03836.15 EAQ88478.1 - 3.4 7.8 26.0 4.6 7.4 8.2 3.4 2 1 1 3 3 3 0 RasGAP C-terminus Golgin_A5 PF09787.9 EAQ88478.1 - 3.5 7.0 53.0 1.9 7.9 14.8 3.1 1 1 2 3 3 3 0 Golgin subfamily A member 5 HrpB7 PF09486.10 EAQ88478.1 - 4.8 7.5 55.7 0.7 10.3 12.6 4.2 2 1 1 3 3 3 0 Bacterial type III secretion protein (HrpB7) Rab5-bind PF09311.11 EAQ88478.1 - 5.9 6.2 49.3 19 4.5 38.8 3.3 1 1 1 2 2 2 0 Rabaptin-like protein DUF812 PF05667.11 EAQ88478.1 - 8.3 5.2 51.7 63 2.2 52.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF812) XLF PF09302.11 EAQ88478.1 - 9.1 6.4 9.5 5.6 7.1 0.7 3.1 2 1 1 3 3 3 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component RVT_1 PF00078.27 EAQ88480.1 - 0.045 13.3 0.0 0.066 12.7 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) GFA PF04828.14 EAQ88481.1 - 7.4e-05 23.0 3.6 7.4e-05 23.0 3.6 2.2 3 0 0 3 3 3 1 Glutathione-dependent formaldehyde-activating enzyme OrfB_Zn_ribbon PF07282.11 EAQ88481.1 - 0.065 13.2 0.1 0.065 13.2 0.1 2.1 2 0 0 2 2 2 0 Putative transposase DNA-binding domain SARAF PF06682.12 EAQ88482.1 - 0.00088 19.0 0.0 0.00098 18.9 0.0 1.1 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis CYYR1 PF10873.8 EAQ88482.1 - 0.0021 18.5 0.0 0.004 17.6 0.0 1.4 1 0 0 1 1 1 1 Cysteine and tyrosine-rich protein 1 ASFV_J13L PF05568.11 EAQ88482.1 - 0.0033 17.2 0.1 0.005 16.6 0.1 1.4 1 0 0 1 1 1 1 African swine fever virus J13L protein DUF4690 PF15756.5 EAQ88482.1 - 0.0046 17.5 0.0 0.012 16.2 0.0 1.7 1 0 0 1 1 1 1 Small Novel Rich in Cartilage Herpes_gE PF02480.16 EAQ88482.1 - 0.024 13.4 0.0 0.027 13.2 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E CD34_antigen PF06365.12 EAQ88482.1 - 0.043 13.4 0.0 0.063 12.8 0.0 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family DUF4448 PF14610.6 EAQ88482.1 - 0.073 12.8 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) PepSY_TM PF03929.16 EAQ88482.1 - 0.083 12.6 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 PepSY-associated TM region Ni_hydr_CYTB PF01292.20 EAQ88482.1 - 0.086 12.4 0.0 0.098 12.2 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 EphA2_TM PF14575.6 EAQ88482.1 - 0.092 13.6 0.2 0.15 12.9 0.2 1.5 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain CcmD PF04995.14 EAQ88482.1 - 0.13 12.4 0.3 0.31 11.1 0.3 1.7 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) Amnionless PF14828.6 EAQ88482.1 - 0.25 10.1 0.0 0.3 9.9 0.0 1.1 1 0 0 1 1 1 0 Amnionless Syndecan PF01034.20 EAQ88482.1 - 0.4 10.6 1.9 0.72 9.8 1.9 1.3 1 0 0 1 1 1 0 Syndecan domain Peptidase_M20 PF01546.28 EAQ88483.1 - 1e-29 103.7 0.0 6.5e-29 101.1 0.0 2.0 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EAQ88483.1 - 8.3e-15 54.6 0.1 2.1e-14 53.4 0.1 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EAQ88483.1 - 1.7e-05 24.6 0.0 2.9e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Abhydrolase_3 PF07859.13 EAQ88486.1 - 8.4e-29 100.9 0.0 3e-28 99.1 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EAQ88486.1 - 8.3e-06 26.6 3.0 1.2e-05 26.1 3.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.12 EAQ88486.1 - 8.3e-05 21.4 0.0 0.00019 20.2 0.0 1.5 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) COesterase PF00135.28 EAQ88486.1 - 0.0013 17.7 0.0 0.022 13.7 0.0 2.0 2 0 0 2 2 2 1 Carboxylesterase family Peptidase_S9 PF00326.21 EAQ88486.1 - 0.038 13.5 0.0 0.063 12.7 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Thioesterase PF00975.20 EAQ88486.1 - 0.12 12.5 0.0 0.17 11.9 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain Glyco_hydro_31 PF01055.26 EAQ88487.1 - 1.1e-93 314.8 8.1 1.5e-93 314.4 8.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 DUF4968 PF16338.5 EAQ88487.1 - 0.0077 16.5 0.0 0.016 15.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4968) Clr5 PF14420.6 EAQ88488.1 - 3.2e-21 75.3 1.0 8.2e-21 74.0 1.0 1.8 1 0 0 1 1 1 1 Clr5 domain TPR_12 PF13424.6 EAQ88488.1 - 0.0027 17.9 0.0 0.011 16.1 0.0 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat Methyltransf_23 PF13489.6 EAQ88490.1 - 4.7e-18 65.6 0.0 6.6e-18 65.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAQ88490.1 - 4.3e-11 43.4 0.0 1.1e-10 42.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EAQ88490.1 - 1.6e-09 38.3 0.0 2.9e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAQ88490.1 - 7.7e-07 29.0 0.0 0.029 14.2 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 EAQ88490.1 - 3.6e-06 27.6 0.0 1.1e-05 26.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EAQ88490.1 - 0.0018 17.7 0.0 0.023 14.0 0.0 2.1 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 EAQ88490.1 - 0.021 14.3 0.0 0.037 13.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain FtsJ PF01728.19 EAQ88490.1 - 0.035 14.2 0.0 0.22 11.6 0.0 2.1 2 0 0 2 2 2 0 FtsJ-like methyltransferase Methyltransf_16 PF10294.9 EAQ88490.1 - 0.038 13.7 0.0 0.057 13.1 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_2 PF00891.18 EAQ88490.1 - 0.073 12.4 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_4 PF02390.17 EAQ88490.1 - 0.094 12.2 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase PrmA PF06325.13 EAQ88490.1 - 0.11 11.9 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) NmrA PF05368.13 EAQ88491.1 - 5.9e-11 42.4 0.1 1.3e-09 38.0 0.1 2.1 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EAQ88491.1 - 2e-09 37.6 0.0 3.1e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Aldo_ket_red PF00248.21 EAQ88492.1 - 3.3e-51 174.2 0.0 1e-50 172.6 0.0 1.6 1 1 0 1 1 1 1 Aldo/keto reductase family Hydrolase_6 PF13344.6 EAQ88493.1 - 1.3e-21 76.6 0.0 2.4e-21 75.8 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EAQ88493.1 - 8.4e-20 70.6 0.0 2e-19 69.4 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.6 EAQ88493.1 - 0.043 13.9 0.0 0.42 10.7 0.0 2.1 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 EAQ88493.1 - 0.14 11.7 0.0 0.33 10.6 0.0 1.6 1 0 0 1 1 1 0 Mitochondrial PGP phosphatase Apt1 PF10351.9 EAQ88493.1 - 0.25 10.1 0.1 1.4 7.7 0.0 1.8 2 0 0 2 2 2 0 Golgi-body localisation protein domain AMP-binding PF00501.28 EAQ88494.1 - 1.6e-76 257.6 0.1 4.1e-47 160.7 0.1 2.5 1 1 1 2 2 2 2 AMP-binding enzyme ketoacyl-synt PF00109.26 EAQ88494.1 - 2.6e-61 207.4 0.0 8.2e-61 205.8 0.0 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 EAQ88494.1 - 1.1e-58 198.1 0.9 2.6e-58 196.9 0.9 1.7 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.21 EAQ88494.1 - 4.9e-56 190.6 0.0 8.1e-56 189.8 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain NAD_binding_4 PF07993.12 EAQ88494.1 - 1.9e-28 99.4 0.0 7.7e-28 97.3 0.0 1.9 1 1 0 1 1 1 1 Male sterility protein Ketoacyl-synt_C PF02801.22 EAQ88494.1 - 5.3e-15 55.5 0.2 5.3e-15 55.5 0.2 2.0 2 0 0 2 2 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 EAQ88494.1 - 1.4e-14 54.5 0.0 3.7e-14 53.1 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension AMP-binding_C PF13193.6 EAQ88494.1 - 7.4e-08 33.3 0.3 2.8e-07 31.4 0.3 2.1 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain adh_short PF00106.25 EAQ88494.1 - 2.5e-07 30.4 0.1 8.2e-07 28.7 0.1 1.9 1 0 0 1 1 1 1 short chain dehydrogenase Thiolase_N PF00108.23 EAQ88494.1 - 5.7e-05 22.6 0.4 0.00012 21.6 0.4 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain NmrA PF05368.13 EAQ88494.1 - 0.058 12.9 0.1 0.11 12.1 0.1 1.4 1 0 0 1 1 1 0 NmrA-like family NmrA PF05368.13 EAQ88495.1 - 3.5e-14 52.9 0.0 1.2e-11 44.6 0.0 2.3 1 1 1 2 2 2 2 NmrA-like family KR PF08659.10 EAQ88495.1 - 1.1e-07 31.9 0.2 2.2e-06 27.7 0.0 2.2 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.6 EAQ88495.1 - 0.044 13.7 0.4 0.78 9.6 0.0 2.7 2 1 1 3 3 3 0 NAD(P)H-binding Epimerase PF01370.21 EAQ88495.1 - 0.048 13.1 0.0 0.63 9.5 0.0 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.17 EAQ88495.1 - 0.051 14.2 0.0 0.15 12.6 0.0 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 3Beta_HSD PF01073.19 EAQ88495.1 - 0.21 10.6 0.1 0.71 8.8 0.0 1.8 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family PhyH PF05721.13 EAQ88496.1 - 4.5e-35 121.8 0.0 8.7e-35 120.9 0.0 1.5 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Mem_trans PF03547.18 EAQ88496.1 - 0.00015 20.3 0.2 0.00024 19.6 0.2 1.3 1 0 0 1 1 1 1 Membrane transport protein T4SS_CagC PF16943.5 EAQ88496.1 - 0.048 13.8 0.2 0.11 12.6 0.2 1.6 1 0 0 1 1 1 0 Cag pathogenicity island, type IV secretory system DUF1479 PF07350.12 EAQ88496.1 - 0.15 10.8 0.0 0.25 10.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1479) NAD_binding_10 PF13460.6 EAQ88497.1 - 2.8e-12 46.9 0.0 4.1e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EAQ88497.1 - 7e-08 32.3 0.0 1.1e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 EAQ88497.1 - 0.011 14.8 0.0 0.015 14.3 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EAQ88497.1 - 0.15 11.5 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family ChapFlgA_N PF17656.1 EAQ88498.1 - 4.6 7.5 6.4 2.9 8.1 0.3 3.2 4 0 0 4 4 4 0 FlgA N-terminal domain Abhydrolase_1 PF00561.20 EAQ88501.1 - 8e-12 45.3 0.0 1.3e-11 44.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EAQ88501.1 - 6.9e-06 25.5 0.0 1.1e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 EAQ88501.1 - 5.9e-05 21.9 0.0 9.1e-05 21.3 0.0 1.2 1 0 0 1 1 1 1 Ndr family Abhydrolase_6 PF12697.7 EAQ88501.1 - 0.00021 22.0 0.0 0.00045 20.9 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ank_4 PF13637.6 EAQ88507.1 - 1.8e-10 41.2 0.3 0.083 13.5 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAQ88507.1 - 6.2e-10 38.5 4.2 0.011 16.2 0.1 5.5 6 0 0 6 6 6 2 Ankyrin repeat Ank_2 PF12796.7 EAQ88507.1 - 7.6e-08 32.8 0.1 0.41 11.3 0.1 3.4 3 0 0 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 EAQ88507.1 - 3.9e-07 30.2 0.0 0.035 14.6 0.0 4.0 4 1 0 4 4 4 2 Ankyrin repeat F-box-like PF12937.7 EAQ88507.1 - 0.00049 19.9 0.0 0.0011 18.8 0.0 1.7 1 0 0 1 1 1 1 F-box-like Ank_5 PF13857.6 EAQ88507.1 - 0.0012 19.0 0.4 0.035 14.4 0.1 3.2 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Fip1 PF05182.13 EAQ88508.1 - 2.6e-21 74.8 1.3 5e-21 73.9 1.3 1.4 1 0 0 1 1 1 1 Fip1 motif Nucleoporin_FG PF13634.6 EAQ88509.1 - 3.9e-09 37.2 52.6 5.7e-06 27.1 22.5 3.0 2 1 1 3 3 3 2 Nucleoporin FG repeat region DUF1664 PF07889.12 EAQ88509.1 - 0.011 15.7 1.1 2.7 8.1 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF3584 PF12128.8 EAQ88509.1 - 0.069 10.7 0.2 0.11 10.0 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) RNA_pol_3_Rpc31 PF11705.8 EAQ88510.1 - 1.5e-58 198.8 0.3 1.5e-58 198.8 0.3 1.3 1 1 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Sec7 PF01369.20 EAQ88512.1 - 2.7e-70 235.8 5.1 5.8e-70 234.7 0.6 3.1 3 0 0 3 3 3 1 Sec7 domain DUF1981 PF09324.10 EAQ88512.1 - 2.6e-35 120.1 11.8 1.6e-33 114.4 0.3 5.3 6 0 0 6 6 6 2 Domain of unknown function (DUF1981) DCB PF16213.5 EAQ88512.1 - 3.9e-22 78.8 4.1 1.3e-20 73.8 0.6 3.3 3 0 0 3 3 3 1 Dimerisation and cyclophilin-binding domain of Mon2 Sec7_N PF12783.7 EAQ88512.1 - 4.4e-15 55.9 1.4 4.4e-14 52.7 0.0 3.1 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal 2-oxoacid_dh PF00198.23 EAQ88513.1 - 2e-73 246.7 0.1 2.7e-73 246.3 0.1 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 EAQ88513.1 - 1.1e-18 66.8 0.9 2.8e-18 65.5 0.9 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 EAQ88513.1 - 1.4e-08 34.9 1.1 5e-08 33.2 1.1 2.0 1 0 0 1 1 1 1 e3 binding domain DUF3614 PF12267.8 EAQ88513.1 - 0.0017 18.9 0.1 0.004 17.7 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3614) DEC-1_N PF04625.13 EAQ88513.1 - 0.32 10.0 3.6 0.2 10.7 1.6 1.6 2 0 0 2 2 2 0 DEC-1 protein, N-terminal region Zn_clus PF00172.18 EAQ88514.1 - 1.8e-08 34.3 11.6 6.4e-08 32.6 11.6 2.0 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EAQ88514.1 - 0.00037 19.6 0.0 0.00054 19.1 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_11 PF00457.17 EAQ88515.1 - 4.9e-77 257.6 18.7 5.8e-77 257.3 18.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 GAS PF13851.6 EAQ88519.1 - 0.00065 19.1 16.1 0.00065 19.1 16.1 1.9 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding Spc29 PF17082.5 EAQ88519.1 - 0.033 14.1 0.9 0.062 13.1 0.9 1.5 1 0 0 1 1 1 0 Spindle Pole Component 29 Clr2 PF10383.9 EAQ88519.1 - 0.04 14.7 0.0 0.099 13.4 0.0 1.7 1 0 0 1 1 1 0 Transcription-silencing protein Clr2 Glu-tRNAGln PF02686.15 EAQ88519.1 - 0.15 12.4 0.3 1.5 9.2 0.0 2.8 3 1 0 3 3 3 0 Glu-tRNAGln amidotransferase C subunit HAUS-augmin3 PF14932.6 EAQ88519.1 - 0.18 11.4 14.7 0.3 10.6 14.7 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 TMF_DNA_bd PF12329.8 EAQ88519.1 - 1.7 8.7 14.0 0.21 11.6 4.1 2.6 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding KASH_CCD PF14662.6 EAQ88519.1 - 2.2 8.1 23.0 1.8 8.4 18.4 2.0 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH zf-C4H2 PF10146.9 EAQ88519.1 - 3.6 7.8 10.8 6.1 7.1 8.8 2.2 1 1 1 2 2 2 0 Zinc finger-containing protein DUF4201 PF13870.6 EAQ88519.1 - 6.5 6.4 20.4 5.9 6.6 4.3 3.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4201) DUF3450 PF11932.8 EAQ88519.1 - 7.5 5.8 19.0 0.55 9.5 4.0 2.7 1 1 1 3 3 3 0 Protein of unknown function (DUF3450) ERM PF00769.19 EAQ88519.1 - 8.1 6.2 26.3 30 4.3 25.6 1.9 1 1 1 2 2 2 0 Ezrin/radixin/moesin family zf-MYND PF01753.18 EAQ88520.1 - 0.0027 17.7 7.2 0.0027 17.7 7.2 2.2 2 0 0 2 2 2 1 MYND finger Whib PF02467.16 EAQ88520.1 - 1.7 9.3 10.3 5.3 7.7 2.9 2.8 2 0 0 2 2 2 0 Transcription factor WhiB YppG PF14179.6 EAQ88521.1 - 4.4 8.1 8.4 5.8 7.7 8.4 1.4 1 1 0 1 1 1 0 YppG-like protein Ferritin_2 PF13668.6 EAQ88522.1 - 3.6e-15 56.4 0.0 7.1e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 Ferritin-like domain DUF1145 PF06611.12 EAQ88522.1 - 0.11 12.5 2.2 5.6 7.0 0.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1145) p450 PF00067.22 EAQ88523.1 - 3.2e-50 171.2 0.0 1.4e-49 169.1 0.0 1.8 2 0 0 2 2 2 1 Cytochrome P450 Mannosyl_trans3 PF11051.8 EAQ88525.1 - 4.6e-44 150.8 0.0 9.7e-27 94.0 0.0 2.2 1 1 1 2 2 2 2 Mannosyltransferase putative adh_short PF00106.25 EAQ88527.1 - 1.3e-08 34.5 0.0 3.4e-08 33.2 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 EAQ88527.1 - 9.6e-05 22.4 0.0 0.00017 21.5 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 EAQ88527.1 - 0.053 13.1 0.0 0.084 12.4 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase PS-DH PF14765.6 EAQ88528.1 - 1.3e-58 198.6 0.1 2.4e-58 197.8 0.1 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 EAQ88528.1 - 5.9e-57 192.5 1.2 1.9e-56 190.8 0.1 2.5 3 0 0 3 3 2 1 KR domain ketoacyl-synt PF00109.26 EAQ88528.1 - 6e-54 183.3 0.3 6e-54 183.3 0.3 2.6 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 EAQ88528.1 - 3.8e-45 154.8 0.0 7.2e-45 153.9 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EAQ88528.1 - 5.8e-41 139.2 0.1 1.6e-40 137.8 0.1 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N_2 PF13602.6 EAQ88528.1 - 5.3e-18 66.3 0.1 1.8e-17 64.6 0.1 2.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase KAsynt_C_assoc PF16197.5 EAQ88528.1 - 1.2e-15 57.9 0.6 1.1e-09 38.7 0.1 3.4 3 0 0 3 3 3 2 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 EAQ88528.1 - 2.5e-10 40.1 0.0 6e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase ADH_zinc_N PF00107.26 EAQ88528.1 - 5.5e-09 36.1 1.0 1.9e-07 31.1 0.1 3.1 2 1 0 2 2 2 1 Zinc-binding dehydrogenase PP-binding PF00550.25 EAQ88528.1 - 6.7e-06 26.4 0.3 1.8e-05 25.0 0.3 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.23 EAQ88528.1 - 0.0011 18.4 0.4 0.0027 17.1 0.1 1.7 2 0 0 2 2 2 1 Thiolase, N-terminal domain Sacchrp_dh_NADP PF03435.18 EAQ88528.1 - 0.0016 18.7 0.1 0.0044 17.3 0.1 1.8 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain PCMT PF01135.19 EAQ88528.1 - 0.0048 16.7 1.0 1.7 8.4 0.1 3.0 3 0 0 3 3 3 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.12 EAQ88528.1 - 0.0059 17.3 0.1 0.027 15.2 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain Polysacc_synt_2 PF02719.15 EAQ88528.1 - 0.011 14.9 0.0 0.019 14.1 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Epimerase PF01370.21 EAQ88528.1 - 0.047 13.1 0.1 0.084 12.3 0.1 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF166 PF02593.14 EAQ88528.1 - 0.09 12.3 0.0 0.91 9.0 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function Methyltransf_23 PF13489.6 EAQ88528.1 - 0.13 12.1 0.0 0.32 10.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain DUF3632 PF12311.8 EAQ88530.1 - 1.2e-12 48.6 0.8 1.9e-12 48.0 0.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) DUF3632 PF12311.8 EAQ88531.1 - 7.6e-19 68.8 0.1 1.1e-18 68.3 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Cupin_2 PF07883.11 EAQ88532.1 - 6.3e-10 38.6 0.2 1.4e-09 37.5 0.1 1.6 1 1 1 2 2 2 1 Cupin domain Cupin_1 PF00190.22 EAQ88532.1 - 3.5e-07 29.9 0.0 4.3e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_7 PF12973.7 EAQ88532.1 - 0.0075 16.2 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 ChrR Cupin-like domain Pirin PF02678.16 EAQ88532.1 - 0.083 12.9 0.0 0.099 12.6 0.0 1.3 1 0 0 1 1 1 0 Pirin Fungal_trans PF04082.18 EAQ88533.1 - 2.5e-16 59.5 0.1 3.4e-16 59.1 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EAQ88533.1 - 3.2e-09 36.8 9.3 7.2e-09 35.6 9.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_18 PF00704.28 EAQ88536.1 - 3.2e-26 92.8 0.5 3.9e-26 92.5 0.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 zf-C2HC5 PF06221.13 EAQ88538.1 - 7.2e-22 77.1 5.7 1.1e-21 76.6 5.7 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type Tropomodulin PF03250.14 EAQ88538.1 - 0.11 12.5 0.2 0.21 11.6 0.2 1.4 1 0 0 1 1 1 0 Tropomodulin Herpes_LMP2 PF07415.11 EAQ88538.1 - 0.5 9.1 1.7 0.96 8.2 1.7 1.3 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein SIR2 PF02146.17 EAQ88539.1 - 7.3e-32 110.7 0.0 2.3e-09 37.4 0.0 3.2 3 0 0 3 3 3 3 Sir2 family Glyco_hydro_43 PF04616.14 EAQ88541.1 - 3.2e-16 59.5 2.3 4.9e-16 58.9 2.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Pro-kuma_activ PF09286.11 EAQ88543.1 - 3.6e-30 105.1 0.0 7.4e-30 104.1 0.0 1.5 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Gag_MA PF01140.19 EAQ88543.1 - 0.12 12.1 0.1 0.38 10.5 0.1 1.8 1 0 0 1 1 1 0 Matrix protein (MA), p15 Na_H_Exchanger PF00999.21 EAQ88544.1 - 2.9e-18 65.9 47.5 9.5e-18 64.1 32.3 4.3 3 1 0 3 3 3 2 Sodium/hydrogen exchanger family RVT_1 PF00078.27 EAQ88547.1 - 3.6e-35 121.5 0.0 5.2e-35 121.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) AAA_12 PF13087.6 EAQ88548.1 - 5.6e-20 71.8 0.0 1.2e-19 70.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAQ88548.1 - 4.3e-10 39.8 0.0 1.1e-09 38.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 EAQ88548.1 - 0.00016 21.5 0.0 0.002 17.9 0.0 2.7 4 0 0 4 4 4 1 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.6 EAQ88548.1 - 0.0014 18.4 0.0 0.0041 16.9 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain DUF4442 PF14539.6 EAQ88548.1 - 0.055 13.6 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) AAA_22 PF13401.6 EAQ88548.1 - 0.061 13.6 0.0 1.8 8.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain Sugarporin_N PF11471.8 EAQ88549.1 - 1.1 9.3 7.9 0.13 12.3 3.4 1.8 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension Mito_fiss_reg PF05308.11 EAQ88549.1 - 2.2 8.3 8.0 15 5.6 6.2 2.3 2 0 0 2 2 2 0 Mitochondrial fission regulator PLAC8 PF04749.17 EAQ88550.1 - 8.5e-21 74.8 14.2 1e-20 74.5 14.2 1.1 1 0 0 1 1 1 1 PLAC8 family Humanin PF15040.6 EAQ88550.1 - 0.067 12.7 0.2 0.12 11.8 0.2 1.4 1 0 0 1 1 1 0 Humanin family Lactamase_B_2 PF12706.7 EAQ88551.1 - 2.1e-13 50.2 0.6 5.8e-13 48.8 0.6 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EAQ88551.1 - 2.1e-11 44.0 0.1 7.3e-11 42.2 0.1 2.0 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Glyco_hydro_61 PF03443.14 EAQ88552.1 - 1.9e-48 165.1 0.0 2.5e-48 164.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 NAR2 PF16974.5 EAQ88552.1 - 0.14 11.6 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 High-affinity nitrate transporter accessory Ldh_1_C PF02866.18 EAQ88553.1 - 1.5e-45 155.1 0.0 3e-45 154.1 0.0 1.5 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 EAQ88553.1 - 1.3e-44 151.7 0.0 2.3e-44 150.9 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 EAQ88553.1 - 0.00011 21.3 0.0 0.00016 20.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_hydro_4 PF02056.16 EAQ88553.1 - 0.045 13.3 0.4 7 6.2 0.2 2.5 2 1 1 3 3 3 0 Family 4 glycosyl hydrolase Semialdhyde_dh PF01118.24 EAQ88553.1 - 0.1 13.0 0.2 0.43 11.0 0.0 2.1 3 0 0 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain E1-E2_ATPase PF00122.20 EAQ88554.1 - 2.4e-16 59.8 0.3 5.9e-16 58.5 0.0 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 EAQ88554.1 - 1.9e-15 57.7 3.6 2.7e-09 37.6 3.9 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EAQ88554.1 - 0.0017 18.4 1.5 0.0033 17.5 0.0 2.3 3 0 0 3 3 3 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EAQ88554.1 - 0.003 17.3 0.0 0.032 14.0 0.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 EAQ88554.1 - 0.045 13.3 0.1 1.9 7.9 0.0 2.9 3 0 0 3 3 3 0 Sucrose-6F-phosphate phosphohydrolase Cation_ATPase_N PF00690.26 EAQ88554.1 - 0.053 13.2 0.0 0.32 10.7 0.0 2.3 2 0 0 2 2 2 0 Cation transporter/ATPase, N-terminus DUF4059 PF13268.6 EAQ88554.1 - 0.73 10.3 3.9 29 5.2 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF4059) MRP-S26 PF14943.6 EAQ88554.1 - 6.5 6.6 11.2 15 5.5 11.2 1.5 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 Whi5 PF08528.11 EAQ88555.1 - 3.5e-10 39.3 0.0 5.7e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 Whi5 like AA_permease_2 PF13520.6 EAQ88556.1 - 1.4e-74 251.5 28.3 1.7e-74 251.2 28.3 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EAQ88556.1 - 4.9e-11 41.9 23.6 3.4e-10 39.1 23.6 2.0 1 1 0 1 1 1 1 Amino acid permease V-SNARE_C PF12352.8 EAQ88557.1 - 4.7e-15 55.6 0.4 1e-14 54.6 0.4 1.5 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 EAQ88557.1 - 0.0011 18.8 0.0 0.0025 17.7 0.0 1.5 1 0 0 1 1 1 1 Sec20 Sigma70_r4 PF04545.16 EAQ88557.1 - 0.015 14.8 0.1 0.032 13.7 0.1 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 TPR_MLP1_2 PF07926.12 EAQ88557.1 - 4.2 7.5 5.5 4.6 7.3 0.8 2.6 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein TPK_catalytic PF04263.16 EAQ88558.1 - 8.9e-28 96.8 0.0 1.3e-27 96.2 0.0 1.2 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 EAQ88558.1 - 1.8e-24 85.2 0.0 2.9e-24 84.5 0.0 1.4 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain CHCH PF06747.13 EAQ88560.1 - 2.8e-05 24.1 0.4 5.3e-05 23.2 0.4 1.5 1 0 0 1 1 1 1 CHCH domain DUF5353 PF17304.2 EAQ88561.1 - 3.3e-10 39.5 5.8 3.3e-10 39.5 5.8 1.6 1 1 1 2 2 2 1 Family of unknown function (DUF5353) Herpes_UL56 PF04534.12 EAQ88561.1 - 0.0066 16.0 5.6 0.0083 15.6 5.6 1.1 1 0 0 1 1 1 1 Herpesvirus UL56 protein Spc7_N PF15402.6 EAQ88561.1 - 0.11 10.8 8.9 0.13 10.5 8.9 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 MCU PF04678.13 EAQ88561.1 - 0.13 12.3 1.1 0.17 12.0 1.1 1.2 1 0 0 1 1 1 0 Mitochondrial calcium uniporter DUF3381 PF11861.8 EAQ88561.1 - 0.27 11.0 4.9 0.35 10.7 4.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) RR_TM4-6 PF06459.12 EAQ88561.1 - 1.1 9.0 5.6 1.4 8.7 5.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF1682 PF07946.14 EAQ88561.1 - 7.6 5.6 9.0 10 5.2 9.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Fungal_trans_2 PF11951.8 EAQ88562.1 - 4.2e-05 22.5 0.0 8.8e-05 21.5 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Prominin PF05478.11 EAQ88563.1 - 0.15 10.0 9.1 0.17 9.8 9.1 1.0 1 0 0 1 1 1 0 Prominin IL22 PF14565.6 EAQ88563.1 - 0.42 10.9 3.5 0.5 10.6 0.9 2.2 1 1 1 2 2 2 0 Interleukin 22 IL-10-related T-cell-derived-inducible factor HIP1_clath_bdg PF16515.5 EAQ88563.1 - 8.3 7.1 14.4 0.43 11.2 4.9 2.2 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF1664 PF07889.12 EAQ88563.1 - 8.4 6.5 7.7 2.4 8.2 2.3 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) Ank_2 PF12796.7 EAQ88564.1 - 8.7e-09 35.9 0.2 6.2e-08 33.1 0.0 2.4 2 1 1 3 3 3 1 Ankyrin repeats (3 copies) Ank PF00023.30 EAQ88564.1 - 4.1e-07 30.1 0.1 0.0025 18.2 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 EAQ88564.1 - 2.6e-06 27.3 0.0 0.00062 20.0 0.0 3.0 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 EAQ88564.1 - 1.2e-05 25.5 0.3 0.0064 16.8 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAQ88564.1 - 0.00018 22.0 0.0 0.025 15.1 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) AAA_22 PF13401.6 EAQ88564.1 - 0.035 14.4 0.0 0.094 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain Dzip-like_N PF13815.6 EAQ88564.1 - 0.13 12.3 0.2 0.36 10.8 0.2 1.7 1 0 0 1 1 1 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal PRCH PF03967.13 EAQ88565.1 - 0.23 11.7 1.6 0.54 10.5 1.0 1.8 1 1 1 2 2 2 0 Photosynthetic reaction centre, H-chain N-terminal region PIF1 PF05970.14 EAQ88566.1 - 6.5e-05 22.3 0.0 8.4e-05 21.9 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase zf-RVT PF13966.6 EAQ88568.1 - 0.1 13.3 0.0 0.35 11.6 0.0 1.9 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase zf-RVT PF13966.6 EAQ88569.1 - 0.025 15.3 0.1 0.05 14.3 0.1 1.6 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase Myb_DNA-bind_3 PF12776.7 EAQ88570.1 - 1e-26 93.7 0.3 1e-26 93.7 0.3 2.6 3 0 0 3 3 2 1 Myb/SANT-like DNA-binding domain TFIIA PF03153.13 EAQ88570.1 - 0.0016 18.6 28.1 0.0027 17.8 28.1 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 EAQ88570.1 - 0.011 15.4 27.9 0.018 14.7 27.9 1.4 1 0 0 1 1 1 0 Spt20 family Rsc14 PF08586.10 EAQ88570.1 - 0.13 13.0 4.5 11 6.9 0.0 2.5 2 0 0 2 2 2 0 RSC complex, Rsc14/Ldb7 subunit DUF4407 PF14362.6 EAQ88570.1 - 0.14 11.4 2.4 0.22 10.8 2.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Neur_chan_memb PF02932.16 EAQ88570.1 - 0.22 11.5 3.0 0.51 10.4 2.8 1.8 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region eIF-3_zeta PF05091.12 EAQ88570.1 - 0.54 9.2 10.8 0.87 8.5 10.8 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) MecA PF05389.12 EAQ88570.1 - 1.3 8.6 5.4 2.2 7.9 5.4 1.3 1 0 0 1 1 1 0 Negative regulator of genetic competence (MecA) DUF2722 PF10846.8 EAQ88570.1 - 1.4 7.8 28.7 3 6.7 28.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) SpoIIP PF07454.11 EAQ88570.1 - 1.8 7.9 7.0 3.1 7.2 7.0 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Rxt3 PF08642.10 EAQ88570.1 - 2.4 8.9 4.7 6 7.6 4.7 1.6 1 0 0 1 1 1 0 Histone deacetylation protein Rxt3 PAT1 PF09770.9 EAQ88570.1 - 3.1 5.9 21.5 4.4 5.4 21.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Band_3_cyto PF07565.13 EAQ88570.1 - 3.5 7.4 7.0 7.3 6.3 7.0 1.5 1 0 0 1 1 1 0 Band 3 cytoplasmic domain CPSF100_C PF13299.6 EAQ88570.1 - 3.6 7.7 6.7 8.2 6.6 6.7 1.6 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Presenilin PF01080.17 EAQ88570.1 - 3.8 6.2 10.7 5.8 5.6 10.7 1.2 1 0 0 1 1 1 0 Presenilin GREB1 PF15782.5 EAQ88570.1 - 5.4 4.0 10.5 7.4 3.6 10.5 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer RR_TM4-6 PF06459.12 EAQ88570.1 - 5.9 6.6 9.5 11 5.7 9.5 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 baeRF_family12 PF18856.1 EAQ88570.1 - 6.4 7.3 9.0 16 6.1 0.0 3.4 3 0 0 3 3 3 0 Bacterial archaeo-eukaryotic release factor family 12 Roughex PF06020.11 EAQ88570.1 - 7.1 5.6 13.7 11 5.0 13.7 1.3 1 0 0 1 1 1 0 Drosophila roughex protein API5 PF05918.11 EAQ88570.1 - 7.8 5.2 9.9 18 4.0 9.9 1.6 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Asp PF00026.23 EAQ88571.1 - 1.2e-37 130.1 0.3 1.4e-37 129.8 0.3 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EAQ88571.1 - 1.5e-05 25.3 0.2 0.0016 18.7 0.3 2.2 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EAQ88571.1 - 0.1 13.2 0.6 0.79 10.4 0.6 2.1 1 1 0 1 1 1 0 Aspartyl protease NACHT PF05729.12 EAQ88572.1 - 0.00017 21.6 0.0 0.001 19.0 0.0 2.2 1 1 0 1 1 1 1 NACHT domain AAA PF00004.29 EAQ88572.1 - 0.055 13.9 0.0 0.16 12.4 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Glyco_hydro_3_C PF01915.22 EAQ88573.1 - 7.8e-51 172.9 0.1 1.3e-50 172.2 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EAQ88573.1 - 2.7e-39 135.4 0.0 4.3e-39 134.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EAQ88573.1 - 4.2e-26 90.9 0.0 9.6e-26 89.7 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain Pkinase PF00069.25 EAQ88575.1 - 1.6e-15 57.2 0.0 3.5e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ88575.1 - 7.1e-12 45.1 0.0 1.3e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase DUF2207 PF09972.9 EAQ88575.1 - 0.00031 19.6 0.1 0.00045 19.1 0.1 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) CorA PF01544.18 EAQ88575.1 - 0.0073 15.7 13.5 0.32 10.3 6.6 3.0 1 1 0 2 2 2 2 CorA-like Mg2+ transporter protein COesterase PF00135.28 EAQ88576.1 - 6.5e-88 295.8 0.0 1.1e-87 295.1 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EAQ88576.1 - 6.7e-07 29.4 0.2 5.7e-06 26.3 0.2 2.4 2 1 0 2 2 2 1 alpha/beta hydrolase fold IIGP PF05049.13 EAQ88576.1 - 2.1e-06 27.0 0.0 3.2e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) UvrD_C_2 PF13538.6 EAQ88576.1 - 0.0026 17.5 0.0 0.0083 15.9 0.0 1.9 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Peptidase_S9 PF00326.21 EAQ88576.1 - 0.014 14.9 0.0 0.027 14.0 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family MMR_HSR1 PF01926.23 EAQ88576.1 - 0.063 13.4 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase Chromo PF00385.24 EAQ88577.1 - 7.4e-13 48.2 0.3 1.4e-12 47.3 0.3 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Gly_transf_sug PF04488.15 EAQ88577.1 - 7.5e-06 26.5 0.0 1.5e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif DUF1918 PF08940.11 EAQ88577.1 - 0.11 12.2 0.4 0.32 10.6 0.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) Tannase PF07519.11 EAQ88578.1 - 5.7e-86 289.3 0.0 6.5e-86 289.1 0.0 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.21 EAQ88578.1 - 4.9e-05 22.9 0.1 0.15 11.5 0.1 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Esterase PF00756.20 EAQ88578.1 - 0.019 14.6 0.0 0.037 13.7 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Abhydrolase_1 PF00561.20 EAQ88578.1 - 0.089 12.4 0.1 0.16 11.6 0.1 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold SH3_3 PF08239.11 EAQ88579.1 - 0.19 12.0 0.0 0.29 11.5 0.0 1.3 1 0 0 1 1 1 0 Bacterial SH3 domain Zn_clus PF00172.18 EAQ88580.1 - 1.7e-05 24.8 8.3 5.5e-05 23.2 8.3 1.9 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3071 PF11268.8 EAQ88580.1 - 0.097 12.7 0.1 2.9 7.9 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3071) Glyco_hydro_3_C PF01915.22 EAQ88582.1 - 1.9e-44 152.1 0.0 2.9e-44 151.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EAQ88582.1 - 3.6e-33 115.3 0.0 5.2e-33 114.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EAQ88582.1 - 7.1e-08 32.5 0.0 1.5e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain SR-25 PF10500.9 EAQ88583.1 - 0.72 9.4 7.1 1.1 8.8 7.1 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Aminotran_5 PF00266.19 EAQ88584.1 - 4.5e-13 48.9 0.0 3.1e-12 46.1 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class-V RhoGAP PF00620.27 EAQ88585.1 - 2.2e-14 53.5 0.0 3.8e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain Epimerase PF01370.21 EAQ88586.1 - 1.4e-16 60.7 1.0 2.5e-11 43.5 0.1 2.1 1 1 1 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 EAQ88586.1 - 1e-07 31.4 0.0 0.0048 16.1 0.0 2.3 1 1 1 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.19 EAQ88586.1 - 4.3e-06 26.0 0.0 0.00021 20.4 0.0 2.3 1 1 1 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EAQ88586.1 - 1.6e-05 24.5 0.7 0.00093 18.7 0.1 2.2 1 1 1 2 2 2 2 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EAQ88586.1 - 0.082 12.8 0.0 0.89 9.4 0.0 2.2 2 0 0 2 2 2 0 NAD(P)H-binding FAD_binding_3 PF01494.19 EAQ88587.1 - 8.4e-17 61.4 2.9 2.7e-08 33.4 0.4 3.4 4 0 0 4 4 4 3 FAD binding domain Pyr_redox PF00070.27 EAQ88587.1 - 0.0028 18.2 0.1 0.0058 17.2 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EAQ88587.1 - 0.0029 17.2 3.0 0.0047 16.6 1.2 2.2 2 1 1 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EAQ88587.1 - 0.0054 16.0 0.1 0.03 13.5 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EAQ88587.1 - 0.027 14.7 0.6 0.065 13.5 0.6 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain zf-RVT PF13966.6 EAQ88588.1 - 0.076 13.7 0.0 0.17 12.6 0.0 1.6 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase F-box PF00646.33 EAQ88589.1 - 0.00048 19.9 0.9 0.0022 17.8 0.1 2.4 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 EAQ88589.1 - 0.0028 17.5 0.1 0.0073 16.2 0.1 1.8 1 0 0 1 1 1 1 F-box-like EBP PF05241.12 EAQ88590.1 - 4.2e-55 185.9 9.6 5.2e-55 185.7 9.6 1.0 1 0 0 1 1 1 1 Emopamil binding protein DUF2236 PF09995.9 EAQ88591.1 - 0.049 13.8 0.9 0.2 11.8 0.2 1.9 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2236) His_Phos_2 PF00328.22 EAQ88592.1 - 8.1e-08 32.0 0.1 1.6e-06 27.7 0.0 2.3 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) Methyltransf_23 PF13489.6 EAQ88593.1 - 4.5e-05 23.3 0.0 7e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain GRIM-19 PF06212.12 EAQ88593.1 - 0.099 12.6 0.4 0.18 11.8 0.4 1.4 1 0 0 1 1 1 0 GRIM-19 protein Collagen PF01391.18 EAQ88594.1 - 0.00081 19.1 7.0 0.0012 18.6 7.0 1.2 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) MFS_1 PF07690.16 EAQ88597.1 - 2.8e-34 118.6 9.7 2.8e-34 118.6 9.7 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily UvrD_C_2 PF13538.6 EAQ88598.1 - 0.0091 15.8 0.1 0.035 13.9 0.0 2.1 2 1 0 2 2 2 1 UvrD-like helicase C-terminal domain FAD_binding_4 PF01565.23 EAQ88599.1 - 1.4e-24 86.4 2.3 1.6e-24 86.2 1.2 1.7 1 1 1 2 2 2 1 FAD binding domain BBE PF08031.12 EAQ88599.1 - 4.4e-11 42.7 0.1 8.3e-11 41.8 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like Trypan_PARP PF05887.11 EAQ88601.1 - 0.0024 17.8 140.2 0.0095 15.9 36.1 4.9 1 1 3 4 4 4 2 Procyclic acidic repetitive protein (PARP) BTB PF00651.31 EAQ88601.1 - 0.23 11.7 0.0 0.46 10.7 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain TPR_8 PF13181.6 EAQ88604.1 - 3.1e-05 23.8 0.2 0.013 15.7 0.2 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 EAQ88604.1 - 0.00022 20.9 1.1 0.0019 17.9 0.2 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 EAQ88604.1 - 0.012 15.7 0.4 0.012 15.7 0.4 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 EAQ88604.1 - 0.073 13.9 0.1 0.073 13.9 0.1 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 EAQ88604.1 - 0.12 12.7 0.5 0.62 10.4 0.5 2.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_11 PF13414.6 EAQ88604.1 - 0.13 12.0 0.2 4.2 7.1 0.0 2.7 2 0 0 2 2 2 0 TPR repeat TPR_16 PF13432.6 EAQ88604.1 - 9.2 7.0 8.6 0.46 11.2 0.4 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat GYF PF02213.16 EAQ88605.1 - 5.5e-18 64.4 0.2 1.2e-17 63.2 0.2 1.7 1 0 0 1 1 1 1 GYF domain GYF_2 PF14237.6 EAQ88605.1 - 0.05 13.4 0.0 0.14 12.0 0.0 1.8 1 0 0 1 1 1 0 GYF domain 2 SnoaL PF07366.12 EAQ88606.1 - 6.8e-05 22.7 0.0 0.00011 21.9 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase Virul_fac_BrkB PF03631.15 EAQ88607.1 - 0.034 13.7 5.1 0.055 13.1 5.1 1.2 1 0 0 1 1 1 0 Virulence factor BrkB 5_nucleotid_C PF02872.18 EAQ88608.1 - 1.3e-38 132.6 0.0 2.3e-38 131.9 0.0 1.3 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 EAQ88608.1 - 6e-07 30.2 0.1 1.2e-06 29.2 0.1 1.5 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Acetyltransf_1 PF00583.25 EAQ88609.1 - 9.7e-14 51.6 0.0 1.2e-13 51.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 EAQ88609.1 - 8.5e-09 35.3 0.0 1.5e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 EAQ88609.1 - 8.3e-07 29.4 0.0 1.3e-06 28.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EAQ88609.1 - 1.2e-05 25.2 0.0 1.7e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EAQ88609.1 - 0.023 15.4 0.0 0.027 15.1 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EAQ88609.1 - 0.11 12.6 0.0 0.12 12.5 0.0 1.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Complex1_LYR PF05347.15 EAQ88610.1 - 9.6e-11 41.6 2.5 1.8e-10 40.7 2.5 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 EAQ88610.1 - 5.3e-07 30.3 2.9 1.3e-06 29.1 2.9 1.9 1 1 0 1 1 1 1 Complex1_LYR-like CttA_N PF18244.1 EAQ88610.1 - 0.092 13.2 0.0 0.19 12.2 0.0 1.4 1 0 0 1 1 1 0 Cellulose-binding protein CttA N-terminal domain Complex1_LYR_1 PF13232.6 EAQ88610.1 - 0.37 11.4 0.2 0.37 11.4 0.2 2.1 1 1 1 2 2 2 0 Complex1_LYR-like APH PF01636.23 EAQ88610.1 - 2.2 8.1 9.2 1e+02 2.7 9.2 2.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family Ank_4 PF13637.6 EAQ88611.1 - 1.1e-16 60.9 0.3 1.6e-08 34.9 0.1 4.4 1 1 3 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAQ88611.1 - 1.9e-12 47.6 0.0 0.00037 21.0 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAQ88611.1 - 1.1e-11 43.8 0.2 0.00052 20.3 0.0 4.9 5 0 0 5 5 5 2 Ankyrin repeat Ank PF00023.30 EAQ88611.1 - 9.3e-11 41.7 0.4 0.0015 18.8 0.0 4.5 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 EAQ88611.1 - 3.5e-09 36.7 0.1 0.0054 17.0 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeats (many copies) KilA-N PF04383.13 EAQ88611.1 - 8.2e-06 25.6 0.2 0.00011 22.1 0.2 2.7 1 1 0 1 1 1 1 KilA-N domain Hrs_helical PF12210.8 EAQ88611.1 - 0.21 12.1 5.7 0.085 13.4 1.9 2.2 2 0 0 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate USP8_interact PF08941.10 EAQ88611.1 - 0.22 11.3 2.0 0.56 10.0 2.0 1.6 1 0 0 1 1 1 0 USP8 interacting CREPT PF16566.5 EAQ88611.1 - 0.88 9.7 8.6 0.56 10.4 3.1 2.3 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour TMF_DNA_bd PF12329.8 EAQ88611.1 - 6.5 6.8 14.8 0.57 10.2 9.0 2.3 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding NAD_binding_7 PF13241.6 EAQ88612.1 - 9.8e-33 112.7 0.1 1.4e-32 112.2 0.1 1.2 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 EAQ88612.1 - 1.8e-26 91.6 0.0 2.6e-26 91.0 0.0 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 EAQ88612.1 - 1.1e-14 53.5 0.1 1.8e-14 52.9 0.1 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Pyr_redox_3 PF13738.6 EAQ88612.1 - 0.00091 18.6 0.1 0.0012 18.1 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 EAQ88612.1 - 0.003 17.6 0.0 0.0047 17.0 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase AlaDh_PNT_C PF01262.21 EAQ88612.1 - 0.024 13.9 0.1 0.034 13.5 0.1 1.1 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain LSDAT_prok PF18171.1 EAQ88612.1 - 0.061 12.6 0.1 0.089 12.0 0.1 1.2 1 0 0 1 1 1 0 SLOG in TRPM, prokaryote ThiF PF00899.21 EAQ88612.1 - 0.064 12.6 0.1 0.064 12.6 0.1 1.5 2 0 0 2 2 2 0 ThiF family Urocanase_C PF17392.2 EAQ88612.1 - 0.081 12.4 0.1 0.12 11.8 0.1 1.2 1 0 0 1 1 1 0 Urocanase C-terminal domain FYVE PF01363.21 EAQ88613.1 - 1.4e-20 73.2 27.6 5.8e-16 58.4 9.1 2.9 3 0 0 3 3 3 2 FYVE zinc finger Rbsn PF11464.8 EAQ88613.1 - 1.1e-16 60.2 1.5 3e-16 58.8 1.5 1.8 1 0 0 1 1 1 1 Rabenosyn Rab binding domain zf-AN1 PF01428.16 EAQ88613.1 - 0.0017 18.4 2.3 0.0017 18.4 2.3 3.9 4 1 0 4 4 4 1 AN1-like Zinc finger HypA PF01155.19 EAQ88613.1 - 0.036 14.1 0.1 0.036 14.1 0.1 3.7 3 1 0 4 4 4 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-Di19 PF05605.12 EAQ88613.1 - 0.12 12.7 0.1 0.12 12.7 0.1 3.8 4 0 0 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 EAQ88613.1 - 1.8 9.6 0.0 1.8 9.6 0.0 6.2 5 1 1 6 6 6 0 C2H2-type zinc finger zf-C2H2_9 PF16293.5 EAQ88613.1 - 2.2 8.2 6.0 10 6.1 0.0 3.5 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) CENP-L PF13092.6 EAQ88614.1 - 4.9e-55 186.2 0.0 7.4e-55 185.6 0.0 1.3 1 0 0 1 1 1 1 Kinetochore complex Sim4 subunit Fta1 zf-RING_2 PF13639.6 EAQ88615.1 - 0.026 14.8 0.1 0.06 13.7 0.1 1.6 1 0 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.6 EAQ88615.1 - 0.031 14.2 0.7 0.057 13.4 0.7 1.4 1 0 0 1 1 1 0 zinc-RING finger domain Glyco_hydro_11 PF00457.17 EAQ88616.1 - 3.5e-79 264.6 21.6 4.2e-79 264.3 21.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 UDPG_MGDP_dh_N PF03721.14 EAQ88617.1 - 2.3e-45 154.5 0.1 4.3e-28 98.2 0.0 2.3 2 0 0 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.19 EAQ88617.1 - 2.1e-31 108.0 0.0 3.6e-31 107.2 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.15 EAQ88617.1 - 7.4e-24 84.2 0.0 1.1e-19 70.8 0.0 3.5 3 0 0 3 3 3 2 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Sacchrp_dh_NADP PF03435.18 EAQ88617.1 - 0.00046 20.4 0.0 0.0013 19.0 0.0 1.8 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_Gly3P_dh_N PF01210.23 EAQ88617.1 - 0.011 15.7 0.0 0.84 9.6 0.0 2.9 3 0 0 3 3 3 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.15 EAQ88617.1 - 0.024 14.8 0.1 4.1 7.5 0.1 2.9 3 1 0 3 3 3 0 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 EAQ88617.1 - 0.052 13.4 0.0 0.17 11.7 0.0 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Glycos_transf_1 PF00534.20 EAQ88618.1 - 3.3e-32 111.4 0.0 5.4e-32 110.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EAQ88618.1 - 2.5e-27 95.9 0.1 4e-27 95.3 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EAQ88618.1 - 2.3e-21 76.5 0.0 1.3e-17 64.3 0.0 2.2 2 0 0 2 2 2 2 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 EAQ88618.1 - 3.2e-12 47.2 3.1 3.2e-12 47.2 0.0 2.4 3 1 0 3 3 3 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 EAQ88618.1 - 1.5e-09 38.1 0.0 3.2e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 PRANC PF09372.10 EAQ88619.1 - 0.003 17.8 0.4 0.12 12.7 0.0 2.1 2 0 0 2 2 2 2 PRANC domain RVT_1 PF00078.27 EAQ88620.1 - 3.1e-19 69.4 0.0 5e-19 68.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RecC_C PF17946.1 EAQ88620.1 - 0.046 13.5 1.0 0.11 12.3 1.0 1.6 1 0 0 1 1 1 0 RecC C-terminal domain PIF1 PF05970.14 EAQ88621.1 - 7.5e-30 104.3 0.0 6.8e-23 81.4 0.0 2.1 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 EAQ88621.1 - 2.7e-09 37.0 0.0 4.9e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain Herpes_Helicase PF02689.14 EAQ88621.1 - 4.5e-06 24.9 0.0 0.0023 15.9 0.0 2.1 2 0 0 2 2 2 2 Helicase UvrD_C_2 PF13538.6 EAQ88621.1 - 0.00022 21.0 0.0 0.00047 19.9 0.0 1.5 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 EAQ88621.1 - 0.0005 20.4 0.0 0.00097 19.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain Torsin PF06309.11 EAQ88621.1 - 0.029 14.5 0.0 0.052 13.6 0.0 1.3 1 0 0 1 1 1 0 Torsin Ank_2 PF12796.7 EAQ88622.1 - 1.8e-14 54.1 0.2 4.1e-14 52.9 0.2 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAQ88622.1 - 4.8e-12 46.2 0.1 6.9e-07 29.7 0.1 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAQ88622.1 - 2.1e-11 43.8 2.9 1.3e-06 28.5 0.1 2.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EAQ88622.1 - 5.4e-11 42.4 0.2 6.1e-06 26.4 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat HET PF06985.11 EAQ88622.1 - 3.1e-10 40.6 2.5 7.6e-07 29.6 0.2 3.0 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Ank_3 PF13606.6 EAQ88622.1 - 3e-09 36.4 0.0 0.00036 20.7 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat p450 PF00067.22 EAQ88623.1 - 1.5e-57 195.4 0.0 4.6e-47 160.8 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 Cutinase PF01083.22 EAQ88624.1 - 9.2e-54 182.1 8.6 1.1e-53 181.9 8.6 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 EAQ88624.1 - 1.4e-06 28.1 0.2 1.9e-06 27.6 0.2 1.2 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_1 PF00561.20 EAQ88624.1 - 0.018 14.7 0.4 0.053 13.2 0.1 1.8 2 0 0 2 2 2 0 alpha/beta hydrolase fold Palm_thioest PF02089.15 EAQ88624.1 - 0.049 13.5 0.3 0.058 13.2 0.3 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase VirJ PF06057.11 EAQ88624.1 - 0.11 12.3 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) DUF676 PF05057.14 EAQ88624.1 - 0.11 12.0 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 EAQ88624.1 - 0.14 12.7 0.1 0.15 12.6 0.1 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Lipase_2 PF01674.18 EAQ88624.1 - 1 8.8 4.5 2.7 7.4 4.2 1.7 1 1 0 1 1 1 0 Lipase (class 2) DUF4360 PF14273.6 EAQ88625.1 - 8.3e-45 152.8 0.6 9.9e-45 152.6 0.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) ADP_ribosyl_GH PF03747.14 EAQ88626.1 - 2.4e-63 214.6 3.0 3e-63 214.3 3.0 1.1 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase Sulfate_transp PF00916.20 EAQ88627.1 - 4.5e-64 216.6 3.4 4.5e-64 216.6 3.4 1.4 1 1 0 1 1 1 1 Sulfate permease family STAS PF01740.21 EAQ88627.1 - 2.1e-15 56.4 0.0 3.9e-15 55.5 0.0 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 EAQ88627.1 - 0.013 15.8 0.0 0.034 14.5 0.0 1.7 1 0 0 1 1 1 0 STAS domain DUF3636 PF12331.8 EAQ88628.1 - 7.3e-50 168.7 0.0 1.5e-49 167.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3636) TSC22 PF01166.18 EAQ88628.1 - 0.091 13.1 0.0 0.31 11.4 0.0 1.9 1 0 0 1 1 1 0 TSC-22/dip/bun family DivIC PF04977.15 EAQ88628.1 - 5.2 6.9 5.1 14 5.6 0.0 2.5 1 1 1 2 2 2 0 Septum formation initiator CTP_transf_1 PF01148.20 EAQ88629.1 - 8.7e-78 261.7 23.4 1.1e-77 261.4 23.4 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family Thiolase_N PF00108.23 EAQ88630.1 - 3.3e-66 223.3 0.0 4.3e-66 222.9 0.0 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EAQ88630.1 - 1.2e-40 138.0 0.8 2.6e-40 136.9 0.8 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EAQ88630.1 - 0.058 13.0 1.2 0.15 11.7 0.6 1.9 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 EAQ88630.1 - 0.097 12.5 0.2 6.8 6.6 0.0 2.5 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ACP_syn_III_C PF08541.10 EAQ88630.1 - 0.1 12.8 0.1 0.3 11.3 0.1 1.8 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Glyco_hydro_cc PF11790.8 EAQ88631.1 - 5.2e-76 255.4 1.6 6e-76 255.2 1.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core MFS_1 PF07690.16 EAQ88632.1 - 1.6e-25 89.8 24.4 2.9e-24 85.6 18.5 2.5 2 1 1 3 3 3 2 Major Facilitator Superfamily DUF3397 PF11877.8 EAQ88632.1 - 2.5 8.3 11.2 12 6.2 7.6 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3397) Glyco_hydro_43 PF04616.14 EAQ88633.1 - 4e-105 351.3 0.7 6.4e-105 350.6 0.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 EAQ88633.1 - 3.7e-44 150.9 0.0 5.5e-44 150.3 0.0 1.3 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain Glyco_hydro_32N PF00251.20 EAQ88633.1 - 0.086 12.4 0.0 1.5 8.3 0.0 2.1 1 1 1 2 2 2 0 Glycosyl hydrolases family 32 N-terminal domain GMC_oxred_N PF00732.19 EAQ88634.1 - 2.9e-35 122.1 0.2 2.2e-20 73.3 0.0 2.2 2 0 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.13 EAQ88634.1 - 2.2e-09 38.0 0.0 3.9e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Thi4 PF01946.17 EAQ88634.1 - 5e-06 25.9 0.2 1.4e-05 24.5 0.1 1.7 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 EAQ88634.1 - 8.2e-05 22.8 0.7 0.00019 21.6 0.7 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EAQ88634.1 - 0.00016 21.4 3.0 0.00017 21.3 1.3 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EAQ88634.1 - 0.00034 19.8 0.4 0.00064 18.9 0.1 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 EAQ88634.1 - 0.00041 19.7 0.2 0.0083 15.4 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EAQ88634.1 - 0.00041 19.7 0.5 0.0038 16.5 0.2 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EAQ88634.1 - 0.0052 15.5 0.1 0.084 11.6 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein DUF4473 PF14747.6 EAQ88634.1 - 0.0094 16.5 0.4 0.019 15.5 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4473) Lycopene_cycl PF05834.12 EAQ88634.1 - 0.022 13.8 0.1 0.033 13.2 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_9 PF13454.6 EAQ88634.1 - 0.024 14.6 0.1 0.047 13.7 0.1 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding TrkA_N PF02254.18 EAQ88634.1 - 0.028 14.7 0.3 0.15 12.3 0.2 2.2 2 0 0 2 2 2 0 TrkA-N domain FAD_binding_3 PF01494.19 EAQ88634.1 - 0.038 13.2 0.1 0.06 12.6 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain p450 PF00067.22 EAQ88635.1 - 1.1e-76 258.5 0.0 1.5e-76 258.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.20 EAQ88635.1 - 3.3e-28 98.8 0.0 4.9e-28 98.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 EAQ88635.1 - 9.2e-24 84.3 0.0 2.2e-23 83.0 0.0 1.7 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 EAQ88635.1 - 5.2e-08 33.5 0.0 2e-07 31.6 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 EAQ88635.1 - 0.01 16.1 0.0 0.022 15.0 0.0 1.6 1 0 0 1 1 1 0 Flavodoxin domain Peptidase_S10 PF00450.22 EAQ88636.1 - 1e-78 265.7 0.3 1.4e-78 265.1 0.3 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase Zn_clus PF00172.18 EAQ88637.1 - 4.8e-09 36.2 12.3 1e-08 35.2 12.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Transp_cyt_pur PF02133.15 EAQ88638.1 - 1e-22 80.6 41.5 1.5e-22 80.0 41.5 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Cytochrom_B558a PF05038.13 EAQ88638.1 - 0.64 9.6 5.0 0.34 10.4 0.4 2.4 2 0 0 2 2 2 0 Cytochrome Cytochrome b558 alpha-subunit DUF1294 PF06961.13 EAQ88638.1 - 4.6 7.6 7.3 1.8 8.9 1.6 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1294) Pox_A14 PF05767.12 EAQ88638.1 - 6.8 6.9 15.3 0.39 10.9 3.9 3.7 4 0 0 4 4 4 0 Poxvirus virion envelope protein A14 GMC_oxred_N PF00732.19 EAQ88639.1 - 8.7e-53 179.6 0.0 1.4e-52 178.9 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EAQ88639.1 - 3.6e-27 95.6 0.0 7e-27 94.7 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 EAQ88639.1 - 2.7e-05 24.3 0.3 0.0001 22.5 0.3 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EAQ88639.1 - 4.1e-05 23.3 0.1 0.0002 21.0 0.0 2.2 2 1 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EAQ88639.1 - 0.00022 20.4 0.5 0.00033 19.8 0.5 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 EAQ88639.1 - 0.0011 18.3 0.1 0.0028 16.9 0.1 1.6 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 EAQ88639.1 - 0.0013 17.9 1.2 0.0059 15.7 0.7 2.0 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.6 EAQ88639.1 - 0.0015 17.8 0.8 0.08 12.2 0.5 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Peptidase_S9 PF00326.21 EAQ88639.1 - 0.0016 18.0 0.7 0.0036 16.8 0.7 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 EAQ88639.1 - 0.0079 15.9 0.1 0.017 14.8 0.1 1.6 1 1 0 1 1 1 1 Putative esterase Pyr_redox_2 PF07992.14 EAQ88639.1 - 0.035 13.3 0.8 0.089 12.0 0.5 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EAQ88639.1 - 0.31 9.7 1.0 0.52 8.9 0.5 1.6 2 0 0 2 2 2 0 HI0933-like protein Glyco_hydro_61 PF03443.14 EAQ88640.1 - 5.6e-25 88.5 0.0 7.3e-25 88.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 SpvB PF03534.13 EAQ88640.1 - 0.071 12.3 0.0 0.1 11.8 0.0 1.1 1 0 0 1 1 1 0 Salmonella virulence plasmid 65kDa B protein PIF1 PF05970.14 EAQ88641.1 - 3.7e-29 102.0 0.0 9.2e-23 81.0 0.0 2.2 2 0 0 2 2 2 2 PIF1-like helicase MULE PF10551.9 EAQ88641.1 - 1.1e-23 83.4 0.0 2.3e-23 82.4 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain AAA_30 PF13604.6 EAQ88641.1 - 1.4e-11 44.5 0.0 4.1e-11 43.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAQ88641.1 - 1.4e-05 25.4 0.0 3.3e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 EAQ88641.1 - 0.00054 19.7 0.1 0.0018 18.1 0.0 1.9 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.14 EAQ88641.1 - 0.00074 17.6 0.0 0.0095 13.9 0.0 2.0 2 0 0 2 2 2 1 Helicase Transposase_mut PF00872.18 EAQ88641.1 - 0.0013 17.6 0.0 0.0023 16.8 0.0 1.3 1 0 0 1 1 1 1 Transposase, Mutator family Torsin PF06309.11 EAQ88641.1 - 0.02 15.0 0.0 0.12 12.4 0.0 2.3 2 0 0 2 2 2 0 Torsin OrsD PF12013.8 EAQ88642.1 - 4.5e-13 49.6 0.1 7.3e-13 49.0 0.1 1.3 1 0 0 1 1 1 1 Orsellinic acid/F9775 biosynthesis cluster protein D OrsD PF12013.8 EAQ88643.1 - 4.3e-14 52.9 0.1 5e-14 52.7 0.1 1.0 1 0 0 1 1 1 1 Orsellinic acid/F9775 biosynthesis cluster protein D zf-UBP PF02148.19 EAQ88643.1 - 0.13 12.6 0.1 0.13 12.6 0.1 1.8 2 0 0 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein PQQ PF01011.21 EAQ88645.1 - 1 9.4 6.2 59 3.8 0.1 4.7 4 1 1 5 5 5 0 PQQ enzyme repeat Ctr PF04145.15 EAQ88646.1 - 2.6e-39 135.2 0.3 3.2e-39 134.9 0.3 1.1 1 0 0 1 1 1 1 Ctr copper transporter family YfhO PF09586.10 EAQ88646.1 - 0.59 8.3 5.5 0.13 10.5 2.5 1.3 2 0 0 2 2 2 0 Bacterial membrane protein YfhO DIT1_PvcA PF05141.12 EAQ88647.1 - 1.7e-90 303.2 0.0 2.8e-90 302.5 0.0 1.4 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein p450 PF00067.22 EAQ88647.1 - 3.2e-60 204.2 0.0 4.7e-60 203.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 SEO_C PF14577.6 EAQ88647.1 - 0.11 11.9 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 Sieve element occlusion C-terminus MFS_1 PF07690.16 EAQ88648.1 - 3.5e-37 128.1 33.0 5.5e-37 127.5 33.0 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EAQ88648.1 - 2e-11 43.4 2.9 2e-11 43.4 2.9 2.2 3 0 0 3 3 3 1 Sugar (and other) transporter SPC25 PF06703.11 EAQ88648.1 - 1.7 8.4 3.1 0.69 9.7 0.1 1.8 2 0 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Metallophos PF00149.28 EAQ88650.1 - 3.5e-09 37.5 2.5 6.6e-09 36.6 0.9 2.1 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase YmdB PF13277.6 EAQ88650.1 - 0.0047 16.3 0.0 0.0064 15.9 0.0 1.3 1 0 0 1 1 1 1 YmdB-like protein PGA_cap PF09587.10 EAQ88650.1 - 0.039 13.4 0.2 0.089 12.2 0.2 1.7 1 1 0 1 1 1 0 Bacterial capsule synthesis protein PGA_cap Peptidase_M20 PF01546.28 EAQ88651.1 - 0.00056 19.7 0.8 0.00092 19.0 0.8 1.6 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Sugar_tr PF00083.24 EAQ88652.1 - 4.7e-84 282.8 18.4 5.4e-84 282.6 18.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EAQ88652.1 - 5.7e-18 65.0 25.9 7.7e-17 61.3 18.1 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EAQ88652.1 - 4.3e-08 32.2 24.6 6.1e-05 21.7 8.1 3.2 2 1 1 3 3 3 2 MFS/sugar transport protein Alpha-amylase PF00128.24 EAQ88653.1 - 2.7e-109 365.8 0.0 4e-109 365.2 0.0 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.6 EAQ88653.1 - 0.0026 16.9 0.0 0.0041 16.3 0.0 1.2 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain Malt_amylase_C PF16657.5 EAQ88653.1 - 0.076 13.1 0.0 0.18 11.9 0.0 1.8 1 0 0 1 1 1 0 Maltogenic Amylase, C-terminal domain peroxidase PF00141.23 EAQ88655.1 - 1e-84 283.8 0.0 4.1e-43 147.7 0.0 2.2 2 0 0 2 2 2 2 Peroxidase ABC_membrane PF00664.23 EAQ88656.1 - 2.8e-81 273.2 25.4 1e-43 150.0 12.5 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EAQ88656.1 - 3e-51 173.5 0.1 2.3e-32 112.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EAQ88656.1 - 1.6e-08 34.3 1.2 0.009 15.5 0.0 4.0 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EAQ88656.1 - 4.2e-08 32.8 0.2 0.002 17.8 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain Zeta_toxin PF06414.12 EAQ88656.1 - 4.5e-08 32.6 0.3 0.0013 18.1 0.0 3.2 2 1 0 2 2 2 2 Zeta toxin AAA_22 PF13401.6 EAQ88656.1 - 2.7e-07 30.9 0.1 0.0059 16.9 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EAQ88656.1 - 2.9e-07 31.0 0.3 0.0097 16.3 0.1 2.8 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 EAQ88656.1 - 2.3e-06 27.6 0.2 0.056 13.3 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_25 PF13481.6 EAQ88656.1 - 2.9e-05 23.7 1.9 0.23 11.0 0.2 3.3 3 0 0 3 3 3 2 AAA domain AAA_15 PF13175.6 EAQ88656.1 - 8.2e-05 22.5 0.0 0.22 11.2 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_30 PF13604.6 EAQ88656.1 - 0.00026 20.8 1.2 0.96 9.1 0.1 3.3 3 0 0 3 3 3 2 AAA domain G-alpha PF00503.20 EAQ88656.1 - 0.00047 19.4 0.0 0.53 9.4 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit DUF87 PF01935.17 EAQ88656.1 - 0.002 18.3 0.9 1.4 9.0 0.3 2.4 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_23 PF13476.6 EAQ88656.1 - 0.0023 18.5 0.3 0.46 11.0 0.5 2.8 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EAQ88656.1 - 0.0043 17.2 0.0 2.1 8.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 EAQ88656.1 - 0.0044 16.9 0.1 4.6 7.0 0.1 3.2 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_5 PF07728.14 EAQ88656.1 - 0.0063 16.5 0.1 3.3 7.7 0.0 3.0 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) ABC_ATPase PF09818.9 EAQ88656.1 - 0.012 14.4 2.4 0.18 10.6 0.2 3.0 3 0 0 3 3 3 0 Predicted ATPase of the ABC class ATP-synt_ab PF00006.25 EAQ88656.1 - 0.013 15.2 0.1 5.2 6.6 0.0 2.6 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain PRK PF00485.18 EAQ88656.1 - 0.016 14.9 0.7 0.95 9.2 0.0 2.6 3 0 0 3 3 2 0 Phosphoribulokinase / Uridine kinase family APS_kinase PF01583.20 EAQ88656.1 - 0.019 14.9 0.1 4.1 7.3 0.1 2.4 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA PF00004.29 EAQ88656.1 - 0.023 15.1 0.1 4.3 7.8 0.0 3.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 EAQ88656.1 - 0.029 14.3 0.0 0.25 11.3 0.0 2.1 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_7 PF12775.7 EAQ88656.1 - 0.048 13.2 0.1 9.6 5.7 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_17 PF13207.6 EAQ88656.1 - 0.048 14.1 0.0 2.4 8.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain Ret2_MD PF18528.1 EAQ88656.1 - 0.066 13.6 0.1 0.81 10.1 0.0 2.8 4 0 0 4 4 2 0 RNA editing 3' terminal uridylyl transferase 2 middle domain AAA_18 PF13238.6 EAQ88656.1 - 0.068 13.7 0.0 13 6.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF3987 PF13148.6 EAQ88656.1 - 0.069 12.2 0.1 0.83 8.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) Ploopntkinase3 PF18751.1 EAQ88656.1 - 0.087 12.7 0.2 15 5.4 0.0 2.8 3 0 0 3 3 2 0 P-loop Nucleotide Kinase3 ATPase PF06745.13 EAQ88656.1 - 0.14 11.4 1.1 1.7 7.9 0.2 2.3 2 0 0 2 2 2 0 KaiC RNA_helicase PF00910.22 EAQ88656.1 - 0.15 12.5 0.3 14 6.1 0.0 2.9 3 0 0 3 3 2 0 RNA helicase AAA_24 PF13479.6 EAQ88656.1 - 0.26 11.0 1.4 19 4.9 0.0 2.7 3 0 0 3 3 2 0 AAA domain Fungal_trans PF04082.18 EAQ88657.1 - 3.2e-09 36.2 0.0 2.9e-08 33.1 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Abhydrolase_3 PF07859.13 EAQ88658.1 - 3.6e-23 82.5 0.0 5.6e-23 81.9 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EAQ88658.1 - 2.5e-08 33.2 0.0 4.6e-08 32.3 0.0 1.4 1 1 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 EAQ88658.1 - 0.00025 20.6 0.0 0.00047 19.7 0.0 1.4 1 1 0 1 1 1 1 Prolyl oligopeptidase family FAD_binding_4 PF01565.23 EAQ88661.1 - 1.3e-14 54.1 0.8 3e-14 52.9 0.8 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EAQ88661.1 - 6.1e-06 26.2 0.3 1.2e-05 25.3 0.3 1.4 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.10 EAQ88661.1 - 0.072 12.5 0.4 0.12 11.8 0.4 1.3 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding p450 PF00067.22 EAQ88662.1 - 1.5e-27 96.5 0.0 1.9e-27 96.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ADH_zinc_N PF00107.26 EAQ88664.1 - 3e-05 24.0 0.2 7.1e-05 22.8 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EAQ88664.1 - 0.0015 18.4 1.4 0.0031 17.4 1.4 1.6 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 EAQ88665.1 - 5.1e-13 48.9 0.0 6.5e-13 48.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EAQ88665.1 - 7.5e-07 28.9 0.0 9.4e-07 28.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EAQ88665.1 - 2.9e-06 27.3 0.1 4.2e-06 26.8 0.1 1.2 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.8 EAQ88665.1 - 0.071 12.9 0.0 0.17 11.7 0.0 1.7 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase p450 PF00067.22 EAQ88666.1 - 4e-46 157.7 0.1 4.5e-46 157.6 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 ketoacyl-synt PF00109.26 EAQ88667.1 - 7.9e-81 271.4 0.0 3.5e-80 269.2 0.0 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain AMP-binding PF00501.28 EAQ88667.1 - 7e-69 232.5 0.0 1.2e-68 231.7 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 EAQ88667.1 - 8.7e-67 225.8 0.1 1.3e-66 225.2 0.1 1.2 1 0 0 1 1 1 1 Condensation domain PS-DH PF14765.6 EAQ88667.1 - 9.2e-48 163.0 0.0 1.5e-47 162.3 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 EAQ88667.1 - 3.4e-44 151.6 0.0 6.5e-44 150.7 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 EAQ88667.1 - 5.4e-43 147.0 0.1 6.8e-41 140.2 0.0 2.6 2 0 0 2 2 2 1 KR domain NAD_binding_4 PF07993.12 EAQ88667.1 - 4.3e-36 124.4 0.0 1.2e-35 123.0 0.0 1.8 1 0 0 1 1 1 1 Male sterility protein Ketoacyl-synt_C PF02801.22 EAQ88667.1 - 1.3e-30 105.9 0.1 3.4e-30 104.5 0.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 EAQ88667.1 - 4.9e-16 59.3 0.0 1.4e-15 57.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EAQ88667.1 - 8e-15 55.1 0.0 4.1e-14 52.7 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Epimerase PF01370.21 EAQ88667.1 - 1e-14 54.6 0.0 2.2e-14 53.5 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EAQ88667.1 - 3.4e-14 52.5 0.0 6.8e-14 51.5 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family PP-binding PF00550.25 EAQ88667.1 - 2e-13 50.5 2.1 7.5e-07 29.4 0.0 2.9 2 0 0 2 2 2 2 Phosphopantetheine attachment site Methyltransf_25 PF13649.6 EAQ88667.1 - 4.8e-13 49.6 0.2 4.1e-12 46.6 0.0 2.8 3 0 0 3 3 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EAQ88667.1 - 7.8e-11 42.5 0.0 4.5e-10 40.0 0.0 2.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAQ88667.1 - 1.1e-09 38.3 0.0 3.1e-09 36.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 EAQ88667.1 - 2.3e-07 30.5 0.0 1.4e-06 27.9 0.0 2.4 2 0 0 2 2 1 1 short chain dehydrogenase Thiolase_N PF00108.23 EAQ88667.1 - 5e-06 26.1 0.0 1.1e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain GDP_Man_Dehyd PF16363.5 EAQ88667.1 - 9.4e-05 22.0 0.0 0.00017 21.1 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Ubie_methyltran PF01209.18 EAQ88667.1 - 0.00047 19.6 0.0 0.001 18.5 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family AMP-binding_C PF13193.6 EAQ88667.1 - 0.00065 20.6 0.0 0.0024 18.8 0.0 2.1 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain SAT PF16073.5 EAQ88667.1 - 0.00073 19.3 0.8 0.039 13.7 0.3 2.9 3 0 0 3 3 3 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Methyltransf_16 PF10294.9 EAQ88667.1 - 0.0016 18.2 0.0 0.0036 17.1 0.0 1.5 1 0 0 1 1 1 1 Lysine methyltransferase NAD_binding_10 PF13460.6 EAQ88667.1 - 0.0075 16.2 0.0 0.016 15.1 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding MTS PF05175.14 EAQ88667.1 - 0.014 14.9 0.2 0.16 11.5 0.0 2.6 2 0 0 2 2 2 0 Methyltransferase small domain ACP_syn_III PF08545.10 EAQ88667.1 - 0.028 14.3 0.2 0.09 12.6 0.2 1.9 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Methyltransf_8 PF05148.15 EAQ88667.1 - 0.033 14.0 0.0 0.55 10.0 0.0 2.3 2 0 0 2 2 2 0 Hypothetical methyltransferase Peptidase_S9 PF00326.21 EAQ88668.1 - 0.00046 19.7 0.1 0.00088 18.8 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 EAQ88668.1 - 0.0019 18.8 1.0 0.0051 17.4 1.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2306 PF10067.9 EAQ88670.1 - 6.1e-15 55.7 8.0 6.1e-15 55.7 8.0 1.8 2 0 0 2 2 2 1 Predicted membrane protein (DUF2306) PHO4 PF01384.20 EAQ88670.1 - 0.055 12.5 2.1 0.076 12.0 2.1 1.1 1 0 0 1 1 1 0 Phosphate transporter family DUF3592 PF12158.8 EAQ88670.1 - 8.2 6.5 7.0 0.7 9.9 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3592) adh_short PF00106.25 EAQ88671.1 - 1.7e-35 122.3 0.0 2.1e-35 122.0 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EAQ88671.1 - 2.4e-27 96.0 0.0 3e-27 95.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EAQ88671.1 - 8e-09 35.6 0.1 1.5e-08 34.8 0.1 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EAQ88671.1 - 0.038 13.4 0.1 0.097 12.1 0.1 1.6 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family NAD_binding_3 PF03447.16 EAQ88671.1 - 0.13 12.9 0.1 0.19 12.4 0.1 1.3 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.17 EAQ88671.1 - 0.14 11.2 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain RVT_1 PF00078.27 EAQ88673.1 - 5.2e-36 124.2 0.0 7.2e-36 123.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) p450 PF00067.22 EAQ88674.1 - 6.8e-34 117.4 0.0 1.1e-33 116.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 SurE PF01975.17 EAQ88675.1 - 2.8e-28 99.0 0.2 4.1e-28 98.5 0.2 1.3 1 0 0 1 1 1 1 Survival protein SurE Fungal_lectin PF07938.12 EAQ88677.1 - 1.1e-16 61.1 1.8 1.4e-15 57.5 0.5 2.0 1 1 1 2 2 2 2 Fungal fucose-specific lectin Glyco_trans_1_4 PF13692.6 EAQ88678.1 - 5.2e-08 33.4 0.0 1.1e-07 32.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 EAQ88678.1 - 9.7e-06 25.2 0.0 1.7e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 EAQ88678.1 - 0.047 14.1 0.5 0.18 12.2 0.1 2.2 2 1 0 2 2 2 0 Glycosyl transferase 4-like domain MFS_1 PF07690.16 EAQ88680.1 - 3e-08 33.0 28.7 4.4e-08 32.4 27.9 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugarporin_N PF11471.8 EAQ88680.1 - 0.17 11.9 1.4 0.29 11.1 0.2 2.0 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension Fungal_trans_2 PF11951.8 EAQ88681.1 - 1.4e-31 109.7 1.2 1.9e-31 109.3 1.2 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EAQ88681.1 - 4.3e-08 33.2 7.3 7.9e-08 32.3 7.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Thioredoxin PF00085.20 EAQ88683.1 - 3.7e-26 91.1 0.0 4.4e-26 90.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 EAQ88683.1 - 7.8e-06 25.4 0.0 8e-06 25.4 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 EAQ88683.1 - 2.2e-05 24.7 0.0 3.2e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 EAQ88683.1 - 6.5e-05 23.3 0.3 0.0008 19.8 0.3 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 EAQ88683.1 - 0.00021 21.4 0.0 0.00042 20.4 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 EAQ88683.1 - 0.0015 18.5 0.0 0.002 18.0 0.0 1.3 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_9 PF14595.6 EAQ88683.1 - 0.005 16.6 0.0 0.0057 16.4 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin DIM1 PF02966.16 EAQ88683.1 - 0.066 13.0 0.0 0.074 12.8 0.0 1.1 1 0 0 1 1 1 0 Mitosis protein DIM1 SnoaL_4 PF13577.6 EAQ88684.1 - 4e-10 39.9 0.0 8e-10 38.9 0.0 1.6 2 1 0 2 2 2 1 SnoaL-like domain DUF4763 PF15960.5 EAQ88686.1 - 1.1e-05 24.8 5.0 1.1e-05 24.8 5.0 4.8 3 2 1 4 4 4 1 Domain of unknown function (DUF4763) Spc7 PF08317.11 EAQ88686.1 - 4e-05 22.7 87.5 0.0026 16.7 8.8 5.5 2 1 2 5 5 5 3 Spc7 kinetochore protein CALCOCO1 PF07888.11 EAQ88686.1 - 7.3e-05 21.8 15.4 7.3e-05 21.8 15.4 4.3 2 1 2 4 4 4 2 Calcium binding and coiled-coil domain (CALCOCO1) like Filament PF00038.21 EAQ88686.1 - 0.00039 20.1 66.7 0.0033 17.0 2.0 4.5 2 1 2 4 4 4 2 Intermediate filament protein FlxA PF14282.6 EAQ88686.1 - 0.00074 19.5 1.8 0.00074 19.5 1.8 6.6 3 2 2 6 6 4 2 FlxA-like protein OmpH PF03938.14 EAQ88686.1 - 0.0019 18.5 4.7 0.0019 18.5 4.7 6.2 2 1 2 5 5 4 2 Outer membrane protein (OmpH-like) CENP-F_leu_zip PF10473.9 EAQ88686.1 - 0.0042 17.1 3.5 0.0042 17.1 3.5 7.2 2 2 4 6 6 5 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Golgin_A5 PF09787.9 EAQ88686.1 - 0.0045 16.5 76.7 0.005 16.4 36.5 4.6 2 1 2 5 5 5 2 Golgin subfamily A member 5 ADIP PF11559.8 EAQ88686.1 - 0.0058 16.7 2.3 0.0058 16.7 2.3 7.5 3 2 5 9 9 8 2 Afadin- and alpha -actinin-Binding APC_N_CC PF16689.5 EAQ88686.1 - 0.0089 16.1 3.2 0.0089 16.1 3.2 4.2 4 1 1 5 5 4 1 Coiled-coil N-terminus of APC, dimerisation domain KASH_CCD PF14662.6 EAQ88686.1 - 0.014 15.2 1.9 0.014 15.2 1.9 6.2 3 2 3 6 6 6 0 Coiled-coil region of CCDC155 or KASH DUF5082 PF16888.5 EAQ88686.1 - 0.015 15.6 3.0 0.015 15.6 3.0 7.7 4 2 3 7 7 7 0 Domain of unknown function (DUF5082) HALZ PF02183.18 EAQ88686.1 - 0.017 15.3 0.4 0.017 15.3 0.4 6.9 6 1 1 7 7 7 0 Homeobox associated leucine zipper TMF_TATA_bd PF12325.8 EAQ88686.1 - 0.018 15.3 1.3 0.018 15.3 1.3 8.4 2 1 5 8 8 6 0 TATA element modulatory factor 1 TATA binding APG6_N PF17675.1 EAQ88686.1 - 0.021 15.4 103.1 0.031 14.8 4.9 7.6 1 1 6 7 7 6 0 Apg6 coiled-coil region Med9 PF07544.13 EAQ88686.1 - 0.022 14.8 1.0 0.022 14.8 1.0 6.1 3 2 2 5 5 3 0 RNA polymerase II transcription mediator complex subunit 9 BLOC1_2 PF10046.9 EAQ88686.1 - 0.034 14.4 0.7 0.034 14.4 0.7 7.0 4 2 3 7 7 7 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 PKcGMP_CC PF16808.5 EAQ88686.1 - 0.11 12.4 16.8 2.3 8.1 0.0 6.5 6 0 0 6 6 6 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF4472 PF14739.6 EAQ88686.1 - 0.58 10.9 68.7 2.7 8.8 3.8 8.0 2 2 4 8 8 8 0 Domain of unknown function (DUF4472) Fez1 PF06818.15 EAQ88686.1 - 0.9 10.0 81.6 0.17 12.3 3.5 5.3 2 1 3 5 5 4 0 Fez1 ATG16 PF08614.11 EAQ88686.1 - 1.1 9.4 98.5 0.075 13.2 2.7 6.6 2 1 4 6 6 6 0 Autophagy protein 16 (ATG16) Rab5-bind PF09311.11 EAQ88686.1 - 1.2 8.4 70.8 0.24 10.8 0.9 4.7 3 1 2 5 5 5 0 Rabaptin-like protein Myosin_tail_1 PF01576.19 EAQ88686.1 - 2.9 5.6 87.1 0.0069 14.3 4.6 4.6 2 1 1 4 4 4 0 Myosin tail GAS PF13851.6 EAQ88686.1 - 2.9 7.2 78.7 0.37 10.1 16.1 5.9 2 1 3 5 5 5 0 Growth-arrest specific micro-tubule binding FlaC_arch PF05377.11 EAQ88686.1 - 8.1 6.9 38.4 13 6.2 0.7 10.7 6 3 6 12 12 12 0 Flagella accessory protein C (FlaC) Cyclin PF08613.11 EAQ88691.1 - 2.5e-13 50.7 0.1 5.2e-13 49.7 0.1 1.5 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 EAQ88691.1 - 2e-05 24.4 0.1 3.3e-05 23.6 0.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain DUF5088 PF17008.5 EAQ88691.1 - 0.2 11.3 0.1 0.33 10.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5088) Arrestin_C PF02752.22 EAQ88692.1 - 2.7e-14 53.7 0.0 2.5e-13 50.7 0.0 2.5 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 EAQ88692.1 - 0.00017 21.7 2.7 0.38 10.8 0.0 3.0 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain Aldo_ket_red PF00248.21 EAQ88693.1 - 6.6e-64 215.9 0.0 9.9e-64 215.3 0.0 1.3 1 1 0 1 1 1 1 Aldo/keto reductase family ADH_N PF08240.12 EAQ88694.1 - 4.3e-26 90.9 4.7 6.5e-26 90.3 4.7 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EAQ88694.1 - 6.6e-18 64.9 0.0 1e-17 64.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EAQ88694.1 - 0.0041 18.2 0.0 0.0071 17.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 EAQ88694.1 - 0.02 14.2 0.5 0.034 13.5 0.1 1.5 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Chs7 PF12271.8 EAQ88695.1 - 3.6e-125 417.1 14.1 4.1e-125 416.9 14.1 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone Ribosomal_S6 PF01250.17 EAQ88696.1 - 9.9e-19 67.4 0.0 2.2e-18 66.3 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S6 DUF3716 PF12511.8 EAQ88696.1 - 2.1e-08 34.1 6.2 3.6e-08 33.3 6.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) Cullin_binding PF03556.15 EAQ88697.1 - 1.1e-29 103.3 3.6 1.9e-29 102.5 3.6 1.4 1 0 0 1 1 1 1 Cullin binding PX PF00787.24 EAQ88699.1 - 2.1e-18 66.4 0.1 4.1e-18 65.4 0.1 1.5 1 0 0 1 1 1 1 PX domain Spc110_C PF18520.1 EAQ88699.1 - 0.15 11.7 0.1 0.39 10.3 0.1 1.7 1 0 0 1 1 1 0 Spindle pole body component 110 C-terminal domain Ribosomal_L27A PF00828.19 EAQ88700.1 - 3.7e-29 102.0 0.1 6.5e-29 101.2 0.1 1.4 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A APT PF03440.14 EAQ88701.1 - 0.16 12.0 0.0 0.19 11.7 0.0 1.0 1 0 0 1 1 1 0 Aerolysin/Pertussis toxin (APT) domain Methyltransf_23 PF13489.6 EAQ88703.1 - 4.5e-20 72.1 0.0 8.7e-20 71.2 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAQ88703.1 - 2.6e-13 50.5 0.0 5.2e-13 49.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAQ88703.1 - 5.6e-10 39.2 0.0 1.2e-08 34.8 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EAQ88703.1 - 1e-08 35.7 0.0 1.9e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EAQ88703.1 - 5.2e-07 30.3 0.0 1.7e-06 28.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EAQ88703.1 - 0.0004 19.8 0.0 0.00062 19.1 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.17 EAQ88703.1 - 0.00069 19.1 0.0 0.0021 17.6 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.14 EAQ88703.1 - 0.0015 18.1 0.0 0.0035 16.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_16 PF10294.9 EAQ88703.1 - 0.016 14.9 0.0 0.026 14.3 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase PrmA PF06325.13 EAQ88703.1 - 0.017 14.5 0.0 0.025 14.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.19 EAQ88703.1 - 0.023 14.8 0.0 0.045 13.9 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase NmrA PF05368.13 EAQ88704.1 - 5.2e-33 114.5 0.0 9.5e-33 113.7 0.0 1.4 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EAQ88704.1 - 2.7e-12 47.0 0.1 3.9e-12 46.4 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EAQ88704.1 - 0.00061 19.3 0.1 0.00096 18.7 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 EAQ88704.1 - 0.0086 16.3 0.5 0.019 15.2 0.1 1.8 2 0 0 2 2 2 1 TrkA-N domain 3Beta_HSD PF01073.19 EAQ88704.1 - 0.034 13.2 0.0 0.051 12.6 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 EAQ88704.1 - 0.097 13.1 0.1 0.22 12.0 0.1 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.10 EAQ88704.1 - 0.12 12.2 0.1 0.3 11.0 0.1 1.6 1 0 0 1 1 1 0 KR domain p450 PF00067.22 EAQ88706.1 - 3.1e-52 177.9 0.1 1.9e-48 165.4 0.0 2.1 1 1 1 2 2 2 2 Cytochrome P450 Peptidase_S8 PF00082.22 EAQ88708.1 - 3.8e-11 42.8 0.1 1.4e-10 40.9 0.1 1.8 1 1 0 1 1 1 1 Subtilase family Ank_4 PF13637.6 EAQ88708.1 - 0.0071 16.9 0.6 9.3 7.0 0.0 4.0 5 0 0 5 5 5 1 Ankyrin repeats (many copies) Laminin_II PF06009.12 EAQ88708.1 - 0.14 12.2 2.5 0.57 10.2 2.5 2.0 1 0 0 1 1 1 0 Laminin Domain II MAT1 PF06391.13 EAQ88708.1 - 2.4 7.9 18.9 1.7 8.4 13.7 2.3 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 DUF2508 PF10704.9 EAQ88708.1 - 5.9 7.1 6.6 5.6 7.2 1.8 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2508) Ank_2 PF12796.7 EAQ88709.1 - 1.2e-82 272.5 0.1 2.2e-13 50.6 0.1 10.4 5 2 7 12 12 12 11 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAQ88709.1 - 1.3e-63 210.6 17.7 6.9e-09 36.1 0.1 13.5 8 4 6 15 15 15 11 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAQ88709.1 - 2.7e-55 183.7 15.7 3.2e-10 40.1 0.0 12.7 6 5 7 13 13 13 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAQ88709.1 - 1e-50 163.8 9.8 2.7e-06 27.3 0.0 17.4 18 0 0 18 18 18 10 Ankyrin repeat Ank PF00023.30 EAQ88709.1 - 7.1e-42 140.1 29.2 2.3e-05 24.6 0.0 16.9 19 0 0 19 19 19 10 Ankyrin repeat ZZ PF00569.17 EAQ88709.1 - 0.12 12.2 10.4 0.25 11.2 10.4 1.4 1 0 0 1 1 1 0 Zinc finger, ZZ type GIT_SHD PF08518.11 EAQ88710.1 - 1.2e-05 24.8 0.2 1.2e-05 24.8 0.2 2.7 3 0 0 3 3 3 1 Spa2 homology domain (SHD) of GIT FA_desaturase PF00487.24 EAQ88710.1 - 0.0088 15.9 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Abhydrolase_1 PF00561.20 EAQ88711.1 - 2e-09 37.5 0.1 3.2e-08 33.6 0.0 2.2 1 1 1 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EAQ88711.1 - 2.5e-08 33.5 0.0 0.0005 19.4 0.0 2.3 1 1 1 2 2 2 2 Serine aminopeptidase, S33 DLH PF01738.18 EAQ88711.1 - 2.5e-05 23.9 0.0 4.1e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 EAQ88711.1 - 6.4e-05 22.5 0.2 0.0064 16.0 0.1 2.1 1 1 1 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 EAQ88711.1 - 0.00016 22.3 4.3 0.00016 22.3 4.3 2.7 1 1 2 3 3 3 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 EAQ88711.1 - 0.00033 20.4 0.0 0.00051 19.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 EAQ88711.1 - 0.012 15.5 0.0 0.018 14.8 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase VirJ PF06057.11 EAQ88711.1 - 0.015 15.2 0.0 0.033 14.1 0.0 1.5 1 1 0 1 1 1 0 Bacterial virulence protein (VirJ) DUF915 PF06028.11 EAQ88711.1 - 0.27 10.5 0.0 0.66 9.3 0.0 1.5 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) FAD_binding_3 PF01494.19 EAQ88712.1 - 2.8e-76 257.1 0.0 3.8e-76 256.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 EAQ88712.1 - 1.1e-25 90.6 1.0 2.7e-20 73.1 0.0 2.4 1 1 1 2 2 2 2 Phenol hydroxylase, C-terminal dimerisation domain DAO PF01266.24 EAQ88712.1 - 0.0022 17.6 0.7 0.037 13.6 0.1 2.3 1 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EAQ88712.1 - 0.0035 16.5 0.1 0.01 15.0 0.1 1.8 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 EAQ88712.1 - 0.0043 16.3 0.0 0.0079 15.5 0.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 EAQ88712.1 - 0.013 14.8 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase SE PF08491.10 EAQ88712.1 - 0.017 14.2 0.0 0.061 12.4 0.0 1.8 1 1 0 1 1 1 0 Squalene epoxidase Pyr_redox_2 PF07992.14 EAQ88712.1 - 0.032 13.4 0.1 0.18 11.0 0.1 2.0 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EAQ88712.1 - 0.06 13.6 0.1 0.19 12.0 0.1 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 EAQ88712.1 - 0.077 12.3 0.1 1.1 8.4 0.0 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 EAQ88712.1 - 0.12 11.6 0.1 0.32 10.2 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HpcH_HpaI PF03328.14 EAQ88713.1 - 7.2e-30 103.8 0.0 1.1e-29 103.2 0.0 1.2 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PK PF00224.21 EAQ88713.1 - 0.001 18.1 0.1 0.0016 17.4 0.1 1.2 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain HDPD PF02924.14 EAQ88713.1 - 0.11 12.6 1.4 0.23 11.6 0.2 2.0 2 0 0 2 2 2 0 Bacteriophage lambda head decoration protein D Cyd_oper_YbgE PF09600.10 EAQ88714.1 - 0.043 14.2 0.5 0.14 12.6 0.1 1.9 2 0 0 2 2 2 0 Cyd operon protein YbgE (Cyd_oper_YbgE) Chromo PF00385.24 EAQ88715.1 - 3.2e-12 46.2 0.0 7.1e-12 45.1 0.0 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Integrase_H2C2 PF17921.1 EAQ88715.1 - 2.2e-08 34.0 0.0 4e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 EAQ88715.1 - 0.19 11.9 0.0 0.49 10.7 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger APH PF01636.23 EAQ88716.1 - 3.6e-14 53.3 1.3 5.7e-13 49.3 1.2 2.3 1 1 0 2 2 2 1 Phosphotransferase enzyme family DUF1679 PF07914.11 EAQ88716.1 - 0.0031 16.4 0.0 0.004 16.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) EcKinase PF02958.20 EAQ88716.1 - 0.0078 15.6 0.0 0.011 15.1 0.0 1.1 1 0 0 1 1 1 1 Ecdysteroid kinase NAD_binding_10 PF13460.6 EAQ88718.1 - 2.6e-06 27.5 0.0 2.4e-05 24.3 0.0 2.0 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EAQ88718.1 - 0.0059 16.2 0.0 0.0069 16.0 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.25 EAQ88718.1 - 0.023 14.1 0.1 0.027 13.9 0.1 1.3 1 1 0 1 1 1 0 short chain dehydrogenase ADH_zinc_N PF00107.26 EAQ88718.1 - 0.17 11.9 1.3 0.26 11.3 1.3 1.3 1 1 0 1 1 1 0 Zinc-binding dehydrogenase SSP160 PF06933.11 EAQ88718.1 - 1.4 7.0 8.6 1.7 6.8 8.6 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF5557 PF17712.1 EAQ88718.1 - 1.8 8.6 0.0 1.8 8.6 0.0 2.4 2 1 1 3 3 3 0 Family of unknown function (DUF5557) Osmo_MPGsynth PF09488.10 EAQ88720.1 - 7e-107 357.5 0.0 8.4e-107 357.2 0.0 1.0 1 0 0 1 1 1 1 Mannosyl-3-phosphoglycerate synthase (osmo_MPGsynth) IucA_IucC PF04183.12 EAQ88722.1 - 5.7e-17 62.1 0.6 3.1e-14 53.1 0.1 2.9 2 1 1 3 3 3 2 IucA / IucC family FhuF PF06276.12 EAQ88722.1 - 5.7e-15 56.1 0.0 1.1e-14 55.2 0.0 1.5 1 0 0 1 1 1 1 Ferric iron reductase FhuF-like transporter Peptidase_M24_C PF16188.5 EAQ88722.1 - 0.077 13.1 1.0 0.26 11.4 0.0 2.4 3 0 0 3 3 3 0 C-terminal region of peptidase_M24 MULE PF10551.9 EAQ88724.1 - 2.1e-22 79.4 0.3 8e-22 77.5 0.0 2.2 2 0 0 2 2 2 1 MULE transposase domain DUF5575 PF17738.1 EAQ88724.1 - 0.079 12.0 0.0 0.14 11.1 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5575) Trypan_PARP PF05887.11 EAQ88724.1 - 2.8 7.9 7.4 0.21 11.6 2.5 1.6 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) GGACT PF06094.12 EAQ88726.1 - 2.4e-10 41.0 0.0 2.9e-10 40.8 0.0 1.1 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like GGACT PF06094.12 EAQ88727.1 - 8.7e-13 48.9 0.1 1.1e-12 48.6 0.1 1.2 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like Amidoligase_2 PF12224.8 EAQ88728.1 - 1.5e-16 60.8 0.0 2.2e-16 60.3 0.0 1.2 1 0 0 1 1 1 1 Putative amidoligase enzyme NHL PF01436.21 EAQ88729.1 - 0.0016 18.3 1.3 1.6 8.9 0.1 3.4 4 0 0 4 4 4 2 NHL repeat Ank_5 PF13857.6 EAQ88731.1 - 6.9e-14 51.7 0.1 5.6e-09 36.1 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAQ88731.1 - 1.9e-11 44.3 0.2 2.3e-05 24.8 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAQ88731.1 - 6.1e-09 36.3 0.1 6.8e-05 23.4 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 EAQ88731.1 - 9e-08 32.2 0.2 0.0019 18.5 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 EAQ88731.1 - 1.2e-07 31.5 0.0 0.0031 17.9 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat GPI-anchored PF10342.9 EAQ88732.1 - 2.4e-18 66.7 0.5 2.4e-18 66.7 0.5 2.6 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family TFIIF_beta_N PF17683.1 EAQ88732.1 - 0.12 13.1 0.1 0.15 12.7 0.1 1.3 1 0 0 1 1 1 0 TFIIF, beta subunit N-terminus BUD22 PF09073.10 EAQ88732.1 - 0.21 10.9 9.4 0.24 10.7 9.4 1.1 1 0 0 1 1 1 0 BUD22 eRF1_1 PF03463.15 EAQ88732.1 - 0.63 10.0 3.0 1 9.3 3.0 1.3 1 0 0 1 1 1 0 eRF1 domain 1 Apt1 PF10351.9 EAQ88732.1 - 2 7.2 11.4 2.7 6.8 11.4 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 EAQ88732.1 - 6.2 5.2 9.4 6.4 5.2 9.4 1.1 1 0 0 1 1 1 0 Macoilin family DNA_pol_A_exo1 PF01612.20 EAQ88734.1 - 0.0016 18.2 0.0 0.28 10.9 0.0 2.1 2 0 0 2 2 2 2 3'-5' exonuclease DUF2235 PF09994.9 EAQ88736.1 - 3.6e-70 236.6 0.0 1.1e-67 228.4 0.0 2.1 1 1 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Aldo_ket_red PF00248.21 EAQ88738.1 - 2.7e-40 138.4 0.0 2.6e-32 112.2 0.0 2.0 2 0 0 2 2 2 2 Aldo/keto reductase family AMP-binding PF00501.28 EAQ88739.1 - 1.2e-79 267.9 0.2 2.2e-79 267.1 0.2 1.4 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.26 EAQ88739.1 - 3.6e-67 226.6 0.0 6.6e-67 225.7 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.6 EAQ88739.1 - 2.5e-51 174.7 1.0 8.2e-51 173.0 0.0 2.3 3 0 0 3 3 3 1 Polyketide synthase dehydratase Condensation PF00668.20 EAQ88739.1 - 5e-46 157.3 0.0 7.7e-46 156.7 0.0 1.2 1 0 0 1 1 1 1 Condensation domain Acyl_transf_1 PF00698.21 EAQ88739.1 - 2.2e-43 149.0 0.1 4.3e-43 148.0 0.1 1.4 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 EAQ88739.1 - 4.2e-42 144.1 0.1 1.4e-41 142.3 0.0 1.9 2 0 0 2 2 2 1 KR domain Ketoacyl-synt_C PF02801.22 EAQ88739.1 - 1.9e-29 102.1 0.0 6.1e-29 100.4 0.0 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 EAQ88739.1 - 1.7e-17 63.8 0.1 1.1e-16 61.3 0.0 2.5 3 0 0 3 3 2 1 Ketoacyl-synthetase C-terminal extension Methyltransf_12 PF08242.12 EAQ88739.1 - 1.9e-14 54.2 0.0 4.6e-14 52.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 EAQ88739.1 - 8.5e-13 48.5 0.0 8.4e-05 22.9 0.2 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site Methyltransf_25 PF13649.6 EAQ88739.1 - 2.8e-10 40.7 0.0 1.7e-09 38.2 0.0 2.5 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EAQ88739.1 - 4.6e-10 40.0 0.0 1.8e-09 38.1 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAQ88739.1 - 5.9e-09 35.9 0.0 3.8e-08 33.3 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EAQ88739.1 - 8.6e-07 28.9 0.0 5.1e-06 26.4 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Thiolase_N PF00108.23 EAQ88739.1 - 7.1e-06 25.6 0.1 1.5e-05 24.5 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Ubie_methyltran PF01209.18 EAQ88739.1 - 0.013 14.8 0.0 0.042 13.2 0.0 1.8 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family AMP-binding_C PF13193.6 EAQ88739.1 - 0.03 15.3 0.0 0.19 12.7 0.0 2.6 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain adh_short PF00106.25 EAQ88739.1 - 0.094 12.2 0.0 0.34 10.4 0.0 1.9 2 0 0 2 2 2 0 short chain dehydrogenase CPSF_A PF03178.15 EAQ88740.1 - 2.1e-96 323.1 0.0 4.5e-95 318.7 0.0 2.5 2 1 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.9 EAQ88740.1 - 1.7e-83 280.9 0.5 2.4e-83 280.4 0.5 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term ANAPC4_WD40 PF12894.7 EAQ88740.1 - 0.15 12.4 0.0 0.55 10.6 0.0 1.9 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain CBM_10 PF02013.16 EAQ88741.1 - 0.22 12.0 2.0 0.43 11.1 2.0 1.4 1 0 0 1 1 1 0 Cellulose or protein binding domain COX5B PF01215.19 EAQ88743.1 - 3.7e-58 194.8 0.0 4.9e-58 194.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb zf-C2H2_3 PF13878.6 EAQ88743.1 - 0.13 12.1 1.4 0.23 11.3 1.4 1.4 1 0 0 1 1 1 0 zinc-finger of acetyl-transferase ESCO DUF4604 PF15377.6 EAQ88744.1 - 4e-32 112.0 13.4 4.7e-32 111.8 13.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) Ank_2 PF12796.7 EAQ88745.1 - 1.8e-18 66.9 0.5 1.4e-08 35.2 0.0 2.7 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Clr5 PF14420.6 EAQ88745.1 - 2.2e-15 56.6 1.7 4.3e-15 55.7 1.7 1.4 1 0 0 1 1 1 1 Clr5 domain Ank PF00023.30 EAQ88745.1 - 1.8e-14 53.4 3.1 5.2e-05 23.5 0.0 4.7 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 EAQ88745.1 - 1.5e-13 50.7 0.5 3.2e-06 27.3 0.0 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAQ88745.1 - 3.8e-11 42.2 0.7 0.0054 17.1 0.0 4.7 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 EAQ88745.1 - 8.7e-11 42.1 0.3 0.00031 21.2 0.0 3.3 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Glyco_hydro_16 PF00722.21 EAQ88748.1 - 1.5e-45 154.8 3.7 2.3e-45 154.2 3.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 TAXi_N PF14543.6 EAQ88749.1 - 0.022 15.0 0.0 0.035 14.3 0.0 1.3 1 0 0 1 1 1 0 Xylanase inhibitor N-terminal Myb_DNA-binding PF00249.31 EAQ88750.1 - 0.0025 18.0 0.0 0.016 15.4 0.1 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain MULE PF10551.9 EAQ88751.1 - 1.3e-18 67.2 0.6 3.3e-18 65.9 0.1 1.9 2 0 0 2 2 2 1 MULE transposase domain FCH PF00611.23 EAQ88751.1 - 0.015 15.6 0.4 0.32 11.3 0.0 2.6 1 1 1 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain XkdW PF09636.10 EAQ88751.1 - 0.055 13.6 0.2 0.097 12.8 0.2 1.4 1 0 0 1 1 1 0 XkdW protein Phage_int_SAM_4 PF13495.6 EAQ88751.1 - 0.079 13.4 0.3 6 7.4 0.1 2.5 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain RVT_1 PF00078.27 EAQ88752.1 - 1.7e-35 122.6 0.0 2.6e-35 122.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 EAQ88752.1 - 1.3e-11 44.4 0.0 3e-11 43.2 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RVT_3 PF13456.6 EAQ88752.1 - 0.025 14.4 0.0 0.18 11.6 0.0 2.3 2 0 0 2 2 2 0 Reverse transcriptase-like PurS PF02700.14 EAQ88752.1 - 0.17 12.1 0.0 0.57 10.4 0.0 1.9 1 0 0 1 1 1 0 Phosphoribosylformylglycinamidine (FGAM) synthase NACHT PF05729.12 EAQ88753.1 - 9.9e-06 25.6 0.0 2e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 NACHT domain DUF676 PF05057.14 EAQ88753.1 - 2.3e-05 24.0 0.0 4.2e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DUF829 PF05705.14 EAQ88753.1 - 0.003 17.5 0.1 0.0084 16.0 0.0 1.8 2 1 0 2 2 2 1 Eukaryotic protein of unknown function (DUF829) PGAP1 PF07819.13 EAQ88753.1 - 0.017 14.9 0.0 0.03 14.0 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein AAA_22 PF13401.6 EAQ88753.1 - 0.027 14.8 0.0 0.098 12.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain Cutinase PF01083.22 EAQ88753.1 - 0.09 12.7 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Cutinase CASP_C PF08172.12 EAQ88754.1 - 8.5e-05 22.0 4.2 0.0001 21.7 3.9 1.3 1 1 0 1 1 1 1 CASP C terminal Golgin_A5 PF09787.9 EAQ88754.1 - 0.00086 18.9 4.0 0.001 18.6 4.0 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 5 SseC PF04888.12 EAQ88754.1 - 0.0025 17.5 1.6 0.0028 17.3 1.6 1.1 1 0 0 1 1 1 1 Secretion system effector C (SseC) like family Herpes_UL6 PF01763.16 EAQ88754.1 - 0.0032 16.1 2.0 0.0035 16.0 2.0 1.1 1 0 0 1 1 1 1 Herpesvirus UL6 like SHE3 PF17078.5 EAQ88754.1 - 0.005 16.6 3.6 0.0069 16.1 3.6 1.1 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 DUF4795 PF16043.5 EAQ88754.1 - 0.0051 16.4 0.7 0.0061 16.2 0.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4795) FapA PF03961.13 EAQ88754.1 - 0.0063 15.2 0.8 0.0073 15.0 0.8 1.0 1 0 0 1 1 1 1 Flagellar Assembly Protein A DUF812 PF05667.11 EAQ88754.1 - 0.0086 15.0 3.2 0.0098 14.8 3.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF812) SKA1 PF07160.12 EAQ88754.1 - 0.01 15.7 4.4 0.018 14.9 4.4 1.3 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 ADIP PF11559.8 EAQ88754.1 - 0.012 15.7 8.8 0.022 14.9 8.8 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding GCP_N_terminal PF17681.1 EAQ88754.1 - 0.029 14.0 0.3 0.033 13.8 0.3 1.1 1 0 0 1 1 1 0 Gamma tubulin complex component N-terminal SlyX PF04102.12 EAQ88754.1 - 0.031 14.9 12.5 0.1 13.3 10.7 2.5 1 1 1 2 2 2 0 SlyX Filament PF00038.21 EAQ88754.1 - 0.031 13.8 6.9 0.05 13.2 6.9 1.3 1 0 0 1 1 1 0 Intermediate filament protein TEX13 PF15186.6 EAQ88754.1 - 0.038 13.7 6.1 0.056 13.1 6.1 1.2 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family DUF1043 PF06295.12 EAQ88754.1 - 0.043 13.8 3.4 0.064 13.3 3.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) CREPT PF16566.5 EAQ88754.1 - 0.044 13.9 3.8 0.08 13.1 3.8 1.4 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour Baculo_PEP_C PF04513.12 EAQ88754.1 - 0.046 13.8 5.2 0.066 13.2 5.2 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Mod_r PF07200.13 EAQ88754.1 - 0.051 13.7 5.1 0.092 12.8 5.1 1.4 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Prominin PF05478.11 EAQ88754.1 - 0.053 11.5 2.3 0.077 11.0 2.3 1.2 1 0 0 1 1 1 0 Prominin TMPIT PF07851.13 EAQ88754.1 - 0.054 12.7 3.9 0.072 12.3 3.9 1.1 1 0 0 1 1 1 0 TMPIT-like protein ING PF12998.7 EAQ88754.1 - 0.058 14.0 4.0 0.09 13.4 4.0 1.3 1 0 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding Syntaxin-6_N PF09177.11 EAQ88754.1 - 0.064 13.8 6.1 2.2 8.9 2.5 2.2 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Fib_alpha PF08702.10 EAQ88754.1 - 0.067 13.4 6.0 0.11 12.7 3.5 1.7 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family FAM76 PF16046.5 EAQ88754.1 - 0.069 12.5 1.1 0.081 12.3 1.1 1.0 1 0 0 1 1 1 0 FAM76 protein Atg14 PF10186.9 EAQ88754.1 - 0.069 12.2 6.2 0.089 11.9 4.3 1.8 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 dNK PF01712.19 EAQ88754.1 - 0.072 12.9 0.1 0.095 12.5 0.1 1.1 1 0 0 1 1 1 0 Deoxynucleoside kinase Spc7 PF08317.11 EAQ88754.1 - 0.094 11.6 6.1 0.14 11.0 6.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF3450 PF11932.8 EAQ88754.1 - 0.095 12.0 8.1 0.19 11.0 7.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) ApoLp-III PF07464.11 EAQ88754.1 - 0.1 12.7 4.7 0.11 12.6 3.4 1.6 2 0 0 2 2 1 0 Apolipophorin-III precursor (apoLp-III) Exonuc_VII_L PF02601.15 EAQ88754.1 - 0.1 12.1 4.1 0.13 11.8 4.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF948 PF06103.11 EAQ88754.1 - 0.12 12.6 5.3 0.7 10.2 5.3 2.3 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Apolipoprotein PF01442.18 EAQ88754.1 - 0.16 11.8 10.4 0.29 11.0 10.4 1.6 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF1664 PF07889.12 EAQ88754.1 - 0.17 11.9 5.3 0.25 11.4 2.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) LXG PF04740.12 EAQ88754.1 - 0.21 11.3 6.3 0.099 12.3 4.1 1.6 2 1 0 2 2 1 0 LXG domain of WXG superfamily DHR10 PF18595.1 EAQ88754.1 - 0.43 10.6 12.1 1.1 9.4 12.1 1.7 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain OmpH PF03938.14 EAQ88754.1 - 0.44 10.9 8.3 0.69 10.3 8.0 1.4 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Phasin_2 PF09361.10 EAQ88754.1 - 0.44 10.8 5.1 0.41 10.9 2.9 1.9 1 1 0 1 1 1 0 Phasin protein Seryl_tRNA_N PF02403.22 EAQ88754.1 - 0.53 10.5 6.6 0.62 10.3 4.9 2.0 2 1 0 2 2 1 0 Seryl-tRNA synthetase N-terminal domain Laminin_II PF06009.12 EAQ88754.1 - 0.54 10.3 6.5 1.1 9.3 3.9 2.1 2 0 0 2 2 2 0 Laminin Domain II DUF16 PF01519.16 EAQ88754.1 - 0.56 10.7 4.7 0.91 10.0 4.7 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF16 TMF_DNA_bd PF12329.8 EAQ88754.1 - 0.57 10.2 6.3 1.8 8.6 6.3 1.8 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding USP8_interact PF08941.10 EAQ88754.1 - 0.59 9.9 4.3 0.99 9.2 4.0 1.6 1 1 0 1 1 1 0 USP8 interacting SecA_DEAD PF07517.14 EAQ88754.1 - 0.78 9.0 4.6 2.5 7.3 4.6 1.7 1 1 0 1 1 1 0 SecA DEAD-like domain HisKA_3 PF07730.13 EAQ88754.1 - 0.83 10.2 10.7 0.56 10.8 1.7 3.1 1 1 2 3 3 3 0 Histidine kinase DUF883 PF05957.13 EAQ88754.1 - 0.85 10.3 11.3 0.82 10.3 4.1 2.7 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) BST2 PF16716.5 EAQ88754.1 - 1 10.0 12.0 1.8 9.2 5.4 2.3 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 GAT PF03127.14 EAQ88754.1 - 1.1 9.6 8.6 2.8 8.3 8.6 1.8 1 1 0 1 1 1 0 GAT domain Phage_Mu_Gam PF07352.12 EAQ88754.1 - 1.2 9.1 6.6 0.28 11.1 2.4 2.0 2 1 1 3 3 2 0 Bacteriophage Mu Gam like protein FUSC PF04632.12 EAQ88754.1 - 1.2 7.5 6.6 1.5 7.2 6.6 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Stm1_N PF09598.10 EAQ88754.1 - 1.4 9.9 5.5 3.3 8.6 5.5 1.8 1 1 0 1 1 1 0 Stm1 UPF0242 PF06785.11 EAQ88754.1 - 1.7 8.7 9.1 5.2 7.1 9.3 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Prefoldin PF02996.17 EAQ88754.1 - 2 8.4 7.4 2.7 7.9 3.0 2.4 1 1 1 2 2 2 0 Prefoldin subunit HR1 PF02185.16 EAQ88754.1 - 2.1 8.5 10.2 0.39 10.9 5.5 2.1 2 0 0 2 2 2 0 Hr1 repeat DUF2203 PF09969.9 EAQ88754.1 - 3.5 8.4 5.7 8 7.2 5.7 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) ZapB PF06005.12 EAQ88754.1 - 3.9 8.0 12.0 7.3 7.1 12.0 1.5 1 0 0 1 1 1 0 Cell division protein ZapB DUF4407 PF14362.6 EAQ88754.1 - 4.4 6.6 9.3 7.1 5.9 9.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) WXG100 PF06013.12 EAQ88754.1 - 4.6 7.5 9.1 6.2 7.1 1.2 3.3 2 1 1 3 3 3 0 Proteins of 100 residues with WXG ILVD_EDD PF00920.21 EAQ88756.1 - 3.2e-179 596.8 0.8 4e-179 596.5 0.8 1.0 1 0 0 1 1 1 1 Dehydratase family Glyco_transf_15 PF01793.16 EAQ88757.1 - 1.6e-96 323.4 8.1 3.1e-96 322.4 8.1 1.4 1 1 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase PadR PF03551.14 EAQ88757.1 - 0.034 14.1 0.0 0.071 13.1 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family Tyrosinase PF00264.20 EAQ88759.1 - 1.1e-39 137.1 0.0 2.2e-39 136.0 0.0 1.5 1 1 1 2 2 2 1 Common central domain of tyrosinase DEC-1_C PF04626.13 EAQ88759.1 - 0.44 10.9 4.0 11 6.5 0.1 3.0 2 1 1 3 3 3 0 Dec-1 protein, C terminal region TPR_10 PF13374.6 EAQ88760.1 - 3.2e-75 246.2 0.0 1.3e-11 44.0 0.0 7.9 8 0 0 8 8 7 7 Tetratricopeptide repeat TPR_12 PF13424.6 EAQ88760.1 - 2e-56 188.2 0.1 5.5e-16 58.6 0.0 6.1 1 1 5 6 6 6 6 Tetratricopeptide repeat TPR_7 PF13176.6 EAQ88760.1 - 9.8e-29 97.3 0.1 7.6e-05 22.5 0.0 7.5 8 0 0 8 8 7 5 Tetratricopeptide repeat TPR_2 PF07719.17 EAQ88760.1 - 1.5e-17 62.2 0.0 0.023 14.8 0.0 7.5 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_1 PF00515.28 EAQ88760.1 - 1.1e-15 56.7 0.0 0.014 15.2 0.0 6.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_MalT PF17874.1 EAQ88760.1 - 1.1e-13 51.3 1.5 1.7e-07 30.9 0.0 2.5 1 1 1 2 2 2 2 MalT-like TPR region TPR_16 PF13432.6 EAQ88760.1 - 1.6e-13 51.0 0.3 0.0017 19.0 0.0 7.0 4 2 3 7 7 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 EAQ88760.1 - 3.4e-11 42.7 0.1 0.076 13.4 0.0 5.2 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_4 PF07721.14 EAQ88760.1 - 1.6e-10 40.5 0.0 0.97 10.3 0.0 7.8 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_8 PF13181.6 EAQ88760.1 - 2.5e-10 39.7 0.0 0.75 10.2 0.0 6.8 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 EAQ88760.1 - 2.6e-10 40.7 0.1 0.14 12.7 0.0 5.9 4 2 3 7 7 6 4 Tetratricopeptide repeat PPR PF01535.20 EAQ88760.1 - 4.6e-10 39.1 0.9 0.95 9.9 0.0 6.7 6 0 0 6 6 6 2 PPR repeat TPR_14 PF13428.6 EAQ88760.1 - 4.2e-09 36.5 1.9 6.4 7.9 0.0 8.3 9 0 0 9 9 8 0 Tetratricopeptide repeat NB-ARC PF00931.22 EAQ88760.1 - 1.9e-07 30.6 0.0 2.6e-06 26.8 0.0 2.6 2 1 0 2 2 2 1 NB-ARC domain PPR_1 PF12854.7 EAQ88760.1 - 1.5e-05 24.6 1.2 10 5.9 0.0 6.0 6 0 0 6 6 6 0 PPR repeat Ses_B PF17046.5 EAQ88760.1 - 7.4e-05 22.6 2.0 0.00019 21.3 2.0 1.7 1 0 0 1 1 1 1 SesB domain on fungal death-pathway protein TPR_5 PF12688.7 EAQ88760.1 - 0.00037 20.7 0.0 37 4.6 0.0 4.9 1 1 4 5 5 5 0 Tetratrico peptide repeat TPR_6 PF13174.6 EAQ88760.1 - 0.00066 20.2 0.7 27 5.7 0.0 5.9 6 0 0 6 6 4 0 Tetratricopeptide repeat DUF4747 PF15931.5 EAQ88760.1 - 0.0019 17.9 1.7 0.64 9.6 0.1 3.1 1 1 2 4 4 4 1 Domain of unknown function (DUF4747) Euplotes_phero PF05842.11 EAQ88760.1 - 0.0021 18.7 3.9 40 4.8 0.0 4.9 1 1 4 5 5 5 0 Euplotes octocarinatus mating pheromone protein AAA_25 PF13481.6 EAQ88760.1 - 0.0028 17.2 0.0 0.0055 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain Ntox35 PF15534.6 EAQ88760.1 - 0.0036 17.7 0.1 50 4.4 0.0 4.4 4 0 0 4 4 4 0 Bacterial toxin 35 RPN6_N PF18055.1 EAQ88760.1 - 0.005 17.2 0.5 9.4 6.6 0.0 3.2 2 1 2 4 4 4 0 26S proteasome regulatory subunit RPN6 N-terminal domain TPR_3 PF07720.12 EAQ88760.1 - 0.0054 16.7 0.0 17 5.5 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat PPR_2 PF13041.6 EAQ88760.1 - 0.0063 16.7 0.7 31 4.9 0.0 4.8 5 0 0 5 5 5 0 PPR repeat family DUF1897 PF09005.10 EAQ88760.1 - 0.052 13.0 0.4 2.1 7.9 0.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1897) AAA_16 PF13191.6 EAQ88760.1 - 0.056 13.8 0.7 1.3 9.4 0.1 3.0 2 1 0 2 2 2 0 AAA ATPase domain NACHT PF05729.12 EAQ88760.1 - 0.068 13.1 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 NACHT domain DUF4074 PF13293.6 EAQ88760.1 - 0.083 13.2 0.2 25 5.3 0.0 4.3 5 0 0 5 5 5 0 Domain of unknown function (DUF4074) HemY_N PF07219.13 EAQ88760.1 - 1.3 9.2 14.8 15 5.8 0.0 6.3 5 1 3 8 8 6 0 HemY protein N-terminus DDE_3 PF13358.6 EAQ88761.1 - 1.2e-10 41.4 0.0 2.3e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease PIF1 PF05970.14 EAQ88761.1 - 1.6e-08 34.1 5.7 9.7e-05 21.7 1.0 2.3 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 EAQ88761.1 - 0.0051 16.6 0.3 0.049 13.3 0.3 2.4 3 0 0 3 3 3 1 AAA domain UvrD_C_2 PF13538.6 EAQ88761.1 - 0.017 14.9 0.0 0.044 13.6 0.0 1.7 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain HTH_33 PF13592.6 EAQ88761.1 - 0.054 13.1 0.0 0.17 11.6 0.0 1.8 1 0 0 1 1 1 0 Winged helix-turn helix GRA6 PF05084.13 EAQ88763.1 - 0.0045 17.0 0.1 0.0076 16.2 0.1 1.5 1 0 0 1 1 1 1 Granule antigen protein (GRA6) DUF4834 PF16118.5 EAQ88763.1 - 0.13 13.2 0.0 0.3 12.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) PhzC-PhzF PF02567.16 EAQ88765.1 - 1.6e-41 142.6 0.0 3.2e-41 141.7 0.0 1.5 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Prp19 PF08606.11 EAQ88765.1 - 8.6e-31 105.7 1.9 8.6e-31 105.7 1.9 2.0 2 0 0 2 2 2 1 Prp19/Pso4-like ANAPC4_WD40 PF12894.7 EAQ88765.1 - 7.5e-09 35.8 0.0 0.005 17.1 0.0 4.2 2 2 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EAQ88765.1 - 1.5e-06 28.8 0.5 1.4 9.9 0.0 5.5 5 0 0 5 5 5 2 WD domain, G-beta repeat eIF2A PF08662.11 EAQ88765.1 - 0.00019 21.4 0.0 0.041 13.8 0.0 2.7 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 EAQ88765.1 - 0.0017 17.7 0.0 0.089 12.1 0.0 2.1 1 1 1 2 2 2 1 WD40-like domain V_ATPase_I_N PF18670.1 EAQ88765.1 - 0.065 13.6 1.5 0.18 12.2 1.5 1.7 1 0 0 1 1 1 0 V-type ATPase subunit I, N-terminal domain zf-Nse PF11789.8 EAQ88765.1 - 0.082 12.7 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 EAQ88766.1 - 0.00023 21.1 2.5 0.00068 19.6 2.5 1.8 1 1 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 EAQ88766.1 - 0.0036 17.1 2.3 0.025 14.4 0.5 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EAQ88766.1 - 0.0041 17.0 2.7 0.013 15.4 2.7 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EAQ88766.1 - 0.012 15.4 2.6 0.034 14.0 2.6 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.6 EAQ88766.1 - 0.031 14.4 0.6 0.14 12.3 0.1 2.1 2 0 0 2 2 2 0 Zinc-binding RING-finger zf-C3HC4_2 PF13923.6 EAQ88766.1 - 0.045 13.6 2.0 0.05 13.5 0.2 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EAQ88766.1 - 0.092 12.9 1.0 0.39 10.9 0.2 2.1 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 EAQ88766.1 - 0.11 12.3 3.5 0.21 11.5 1.0 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EAQ88766.1 - 0.12 12.8 3.9 0.16 12.3 1.4 2.1 2 0 0 2 2 2 0 Ring finger domain Prok-RING_1 PF14446.6 EAQ88766.1 - 0.34 10.9 4.4 12 6.0 0.9 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 AIM3 PF17096.5 EAQ88766.1 - 2.1 9.3 10.0 0.27 12.2 0.7 2.7 2 0 0 2 2 2 0 Altered inheritance of mitochondria protein 3 Raptor_N PF14538.6 EAQ88767.1 - 0.00019 21.4 0.0 0.0003 20.8 0.0 1.3 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain Peptidase_C14 PF00656.22 EAQ88767.1 - 0.0015 18.5 0.0 0.0022 18.0 0.0 1.2 1 0 0 1 1 1 1 Caspase domain Pkinase PF00069.25 EAQ88771.1 - 9.5e-23 80.9 0.0 6.7e-11 42.1 0.0 3.3 2 2 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ88771.1 - 9.8e-09 34.9 0.0 0.0018 17.6 0.0 3.8 3 1 0 3 3 3 2 Protein tyrosine kinase APH PF01636.23 EAQ88771.1 - 0.031 14.2 1.2 0.041 13.8 0.1 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Cas_Csy2 PF09614.10 EAQ88771.1 - 0.035 13.5 0.1 0.051 12.9 0.1 1.1 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy2) Kdo PF06293.14 EAQ88771.1 - 0.13 11.6 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FAD_binding_3 PF01494.19 EAQ88774.1 - 4.1e-12 46.0 3.5 3.1e-06 26.7 0.7 3.1 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 EAQ88774.1 - 3e-05 24.2 0.1 5.8e-05 23.3 0.1 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EAQ88774.1 - 0.00037 20.2 0.1 0.001 18.7 0.1 1.7 1 1 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EAQ88774.1 - 0.0016 17.6 0.0 0.0026 16.9 0.0 1.3 1 1 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 EAQ88774.1 - 0.0042 16.4 0.0 0.015 14.5 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EAQ88774.1 - 0.0062 17.1 0.1 0.075 13.6 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EAQ88774.1 - 0.069 12.0 0.1 3.6 6.3 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase DUF202 PF02656.15 EAQ88775.1 - 2.2 8.8 13.6 1.2 9.7 0.3 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF202) MFS_1 PF07690.16 EAQ88777.1 - 1.9e-35 122.5 31.9 7.8e-35 120.4 32.6 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily ESSS PF10183.9 EAQ88777.1 - 0.0052 17.0 0.0 0.069 13.4 0.0 2.6 2 0 0 2 2 2 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) MFS_1 PF07690.16 EAQ88778.1 - 3.3e-43 148.0 51.8 3.3e-43 148.0 51.8 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily HOK_GEF PF01848.16 EAQ88778.1 - 0.1 12.1 1.2 0.41 10.1 1.2 2.0 1 0 0 1 1 1 0 Hok/gef family UBM PF14377.6 EAQ88778.1 - 0.11 11.9 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin binding region Fungal_trans PF04082.18 EAQ88779.1 - 6.7e-13 48.3 0.3 1e-12 47.7 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EAQ88779.1 - 8.6e-09 35.4 7.4 2.1e-08 34.1 7.4 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.25 EAQ88781.1 - 0.031 13.7 0.0 0.32 10.3 0.0 2.0 1 1 1 2 2 2 0 Protein kinase domain TFIIF_alpha PF05793.12 EAQ88781.1 - 0.22 10.1 8.0 0.29 9.7 8.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) HPP PF04982.13 EAQ88782.1 - 2.9e-10 40.4 9.9 2.9e-10 40.4 9.9 2.8 2 1 0 2 2 2 1 HPP family IDO PF01231.18 EAQ88783.1 - 4.5e-34 118.0 0.0 2.4e-30 105.7 0.0 2.0 1 1 1 2 2 2 2 Indoleamine 2,3-dioxygenase Aminotran_5 PF00266.19 EAQ88784.1 - 4.9e-09 35.6 0.0 1e-08 34.6 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 EAQ88784.1 - 0.2 10.9 0.0 0.31 10.3 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 EAQ88784.1 - 0.25 9.9 0.0 0.36 9.3 0.0 1.1 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme rve PF00665.26 EAQ88787.1 - 1.8e-06 28.1 0.0 3.5e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain UbiA PF01040.18 EAQ88787.1 - 4e-06 26.3 0.0 5.7e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF3085 PF11284.8 EAQ88787.1 - 0.043 14.1 0.0 0.096 13.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3085) SP_C-Propep PF08999.10 EAQ88789.1 - 0.086 12.6 1.3 0.27 11.0 0.5 2.2 2 0 0 2 2 2 0 Surfactant protein C, N terminal propeptide GGACT PF06094.12 EAQ88790.1 - 8.3e-19 68.4 0.1 1.3e-18 67.7 0.1 1.3 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like RNA_pol_Rpc4 PF05132.14 EAQ88790.1 - 0.038 14.4 4.5 26 5.2 0.0 2.3 2 0 0 2 2 2 0 RNA polymerase III RPC4 Ribosomal_L12_N PF16320.5 EAQ88792.1 - 0.044 13.5 0.1 0.16 11.7 0.1 1.8 2 0 0 2 2 2 0 Ribosomal protein L7/L12 dimerisation domain DEAD PF00270.29 EAQ88794.1 - 4.6e-20 72.1 0.0 1e-19 71.0 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EAQ88794.1 - 1.9e-17 63.6 0.0 1.5e-15 57.5 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 EAQ88794.1 - 0.037 14.8 0.7 0.095 13.4 0.7 1.7 1 0 0 1 1 1 0 RecQ zinc-binding AAA_22 PF13401.6 EAQ88794.1 - 0.044 14.1 0.0 0.24 11.7 0.0 2.3 3 0 0 3 3 3 0 AAA domain TrbI_Ftype PF09677.10 EAQ88794.1 - 0.05 13.9 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 Type-F conjugative transfer system protein (TrbI_Ftype) TrmB PF01978.19 EAQ88794.1 - 0.061 13.2 0.0 0.17 11.8 0.0 1.8 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB ResIII PF04851.15 EAQ88794.1 - 0.078 13.0 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit SNF2_N PF00176.23 EAQ88794.1 - 0.2 10.3 0.0 0.26 10.0 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain DUF1996 PF09362.10 EAQ88795.1 - 1.7e-80 270.4 0.4 2.1e-80 270.1 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) zf_Rg PF17915.1 EAQ88795.1 - 0.23 10.9 4.5 0.52 9.8 1.1 3.0 4 0 0 4 4 4 0 Reverse gyrase zinc finger Methyltransf_24 PF13578.6 EAQ88796.1 - 3.3e-07 31.3 0.0 5.1e-07 30.7 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.17 EAQ88796.1 - 0.00068 18.9 0.0 0.0029 16.8 0.0 1.9 1 1 0 1 1 1 1 O-methyltransferase Pro-kuma_activ PF09286.11 EAQ88797.1 - 3.6e-46 157.0 0.0 7.4e-45 152.7 0.0 2.3 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 EAQ88797.1 - 0.00074 18.9 0.6 0.0014 17.9 0.6 1.4 1 0 0 1 1 1 1 Subtilase family DUF3215 PF11503.8 EAQ88797.1 - 0.18 11.7 0.0 23 4.9 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3215) Peptidase_C1 PF00112.23 EAQ88799.1 - 1.5e-26 93.8 0.6 1.5e-26 93.8 0.6 2.2 2 0 0 2 2 2 1 Papain family cysteine protease FAD_binding_4 PF01565.23 EAQ88800.1 - 8.1e-15 54.8 1.5 1.5e-14 53.9 1.5 1.4 1 0 0 1 1 1 1 FAD binding domain Flavin_Reduct PF01613.18 EAQ88800.1 - 7.3e-13 48.8 0.0 1.4e-12 47.9 0.0 1.4 1 0 0 1 1 1 1 Flavin reductase like domain BBE PF08031.12 EAQ88800.1 - 0.00013 21.9 0.1 0.0003 20.8 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like DUF4292 PF14125.6 EAQ88802.1 - 0.064 12.9 0.2 0.12 12.0 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4292) CDC73_N PF16050.5 EAQ88802.1 - 0.068 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Paf1 complex subunit CDC73 N-terminal LysM PF01476.20 EAQ88804.1 - 2e-12 47.0 0.0 0.0032 17.5 0.0 3.2 3 0 0 3 3 3 3 LysM domain Rubella_E2 PF05749.11 EAQ88804.1 - 0.025 14.1 0.8 0.025 14.1 0.8 1.9 2 0 0 2 2 2 0 Rubella membrane glycoprotein E2 3-dmu-9_3-mt PF06983.13 EAQ88805.1 - 1.4e-47 161.0 0.0 1.9e-47 160.6 0.0 1.2 1 0 0 1 1 1 1 3-demethylubiquinone-9 3-methyltransferase Hydrolase_4 PF12146.8 EAQ88808.1 - 2.7e-17 62.8 0.0 5.7e-17 61.8 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EAQ88808.1 - 5.8e-16 59.8 2.7 7.2e-16 59.5 2.7 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EAQ88808.1 - 2.1e-13 50.5 0.1 3.1e-10 40.1 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EAQ88808.1 - 0.0038 16.7 0.0 0.0073 15.8 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Chlorophyllase2 PF12740.7 EAQ88808.1 - 0.058 12.3 0.0 0.084 11.8 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Abhydrolase_4 PF08386.10 EAQ88808.1 - 0.07 13.2 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein Tyrosinase PF00264.20 EAQ88809.1 - 7.8e-53 180.0 1.6 7.8e-53 180.0 1.6 1.6 2 0 0 2 2 2 1 Common central domain of tyrosinase Tyosinase_C PF18132.1 EAQ88809.1 - 6.5e-19 68.8 0.0 1.3e-18 67.8 0.0 1.5 1 0 0 1 1 1 1 Tyosinase C-terminal domain zf-RVT PF13966.6 EAQ88810.1 - 0.018 15.7 0.1 0.034 14.9 0.1 1.6 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase O-FucT PF10250.9 EAQ88811.1 - 1.1e-24 87.8 0.0 1.5e-24 87.3 0.0 1.2 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase CAF1C_H4-bd PF12265.8 EAQ88812.1 - 5.3e-14 52.2 0.0 1.8e-13 50.6 0.0 2.0 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 EAQ88812.1 - 7.4e-13 48.8 8.4 1.6e-06 28.7 0.1 4.4 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAQ88812.1 - 1.8e-07 31.3 0.0 0.0039 17.5 0.0 2.7 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Glyco_hydro_43 PF04616.14 EAQ88813.1 - 1.1e-28 100.4 6.4 1.4e-28 100.0 6.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 EAQ88813.1 - 1.2e-18 67.5 2.6 7.7e-15 55.2 0.0 2.3 1 1 1 2 2 2 2 Beta xylosidase C-terminal Concanavalin A-like domain Pkinase PF00069.25 EAQ88814.1 - 1.7e-15 57.1 0.0 2.1e-15 56.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ88814.1 - 0.011 15.1 0.0 0.022 14.0 0.0 1.5 2 0 0 2 2 2 0 Protein tyrosine kinase APH PF01636.23 EAQ88816.1 - 0.0067 16.4 0.9 0.016 15.2 0.9 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EAQ88816.1 - 0.17 11.2 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1524 PF07510.11 EAQ88817.1 - 2.2e-06 27.6 0.0 2.6e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1524) LIDHydrolase PF10230.9 EAQ88818.1 - 0.0019 17.8 0.0 0.003 17.2 0.0 1.2 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_6 PF12697.7 EAQ88818.1 - 0.0031 18.2 0.8 0.0073 16.9 0.8 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 EAQ88818.1 - 0.0064 16.2 0.0 0.032 14.0 0.0 1.9 2 0 0 2 2 2 1 PGAP1-like protein Hydrolase_4 PF12146.8 EAQ88818.1 - 0.074 12.3 0.0 0.2 10.9 0.0 1.8 2 0 0 2 2 2 0 Serine aminopeptidase, S33 zf-RanBP PF00641.18 EAQ88819.1 - 0.0013 18.0 1.7 0.0013 18.0 1.7 1.9 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others Rep_fac-A_C PF08646.10 EAQ88819.1 - 0.049 13.4 1.1 0.067 12.9 1.1 1.1 1 0 0 1 1 1 0 Replication factor-A C terminal domain Pkinase PF00069.25 EAQ88820.1 - 4.4e-06 26.3 0.0 6.1e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 EAQ88820.1 - 0.0046 16.3 0.0 0.0069 15.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EAQ88820.1 - 0.031 14.2 1.8 0.069 13.1 1.8 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 EAQ88820.1 - 0.17 11.2 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase SKG6 PF08693.10 EAQ88822.1 - 4.6e-05 22.7 2.6 7.7e-05 22.0 2.6 1.3 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4381 PF14316.6 EAQ88822.1 - 0.016 15.5 0.3 0.023 14.9 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF4448 PF14610.6 EAQ88822.1 - 0.018 14.9 0.0 0.022 14.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Rax2 PF12768.7 EAQ88822.1 - 0.03 13.8 0.0 0.04 13.4 0.0 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity NPDC1 PF06809.11 EAQ88822.1 - 0.031 13.3 2.3 0.036 13.1 2.3 1.1 1 0 0 1 1 1 0 Neural proliferation differentiation control-1 protein (NPDC1) BatD PF13584.6 EAQ88822.1 - 0.048 12.5 0.1 0.061 12.1 0.1 1.1 1 0 0 1 1 1 0 Oxygen tolerance EphA2_TM PF14575.6 EAQ88822.1 - 0.067 14.1 0.0 0.11 13.4 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Amnionless PF14828.6 EAQ88822.1 - 0.11 11.3 0.0 0.12 11.2 0.0 1.0 1 0 0 1 1 1 0 Amnionless DUF4131 PF13567.6 EAQ88822.1 - 0.19 11.4 1.1 9.5 5.8 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Stevor PF17410.2 EAQ88822.1 - 0.34 10.4 0.5 0.42 10.1 0.5 1.1 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame CcmD PF04995.14 EAQ88822.1 - 0.48 10.6 6.7 1 9.5 6.7 1.5 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) MFS_1 PF07690.16 EAQ88823.1 - 1e-15 57.6 25.4 1.6e-15 56.9 25.4 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Peptidase_M61 PF05299.12 EAQ88826.1 - 1.9e-05 25.0 0.1 3.7e-05 24.1 0.1 1.4 1 0 0 1 1 1 1 M61 glycyl aminopeptidase Oxidored_q6 PF01058.22 EAQ88827.1 - 4.2e-06 26.6 0.1 6.9e-06 25.9 0.1 1.4 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Ank_2 PF12796.7 EAQ88828.1 - 3.1e-10 40.5 0.0 5.7e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAQ88828.1 - 1.3e-09 38.1 0.0 4.7e-05 23.6 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAQ88828.1 - 5e-08 32.6 0.0 0.0004 20.6 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 EAQ88828.1 - 1.1e-07 32.2 0.0 2.3e-05 24.9 0.0 2.6 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Zn_clus PF00172.18 EAQ88828.1 - 5e-06 26.5 6.3 5e-06 26.5 6.3 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ank PF00023.30 EAQ88828.1 - 1e-05 25.8 0.3 0.0095 16.4 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat G6PD_bact PF10786.9 EAQ88828.1 - 0.14 11.7 0.2 0.22 11.1 0.2 1.2 1 0 0 1 1 1 0 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) MFS_1 PF07690.16 EAQ88829.1 - 1.7e-33 116.0 32.5 1.7e-33 116.0 32.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EAQ88829.1 - 1.1e-14 54.1 13.3 1.1e-14 54.1 13.3 2.5 1 1 1 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 EAQ88829.1 - 2.3e-07 29.6 1.9 2.3e-07 29.6 1.9 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Phage_holin_3_5 PF16085.5 EAQ88829.1 - 0.14 12.3 15.0 0.15 12.2 0.0 3.6 3 0 0 3 3 3 0 Bacteriophage holin Hol, superfamily III DUF1269 PF06897.12 EAQ88829.1 - 0.4 11.0 2.1 1.2 9.4 1.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1269) HET PF06985.11 EAQ88830.1 - 1.4e-17 64.4 0.4 1.1e-12 48.5 0.0 2.4 2 0 0 2 2 2 2 Heterokaryon incompatibility protein (HET) DUF3050 PF11251.8 EAQ88830.1 - 0.072 12.7 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3050) Dmd PF17587.2 EAQ88830.1 - 0.074 13.4 0.1 0.23 11.8 0.0 1.8 2 0 0 2 2 2 0 Discriminator of mRNA degradation adh_short PF00106.25 EAQ88831.1 - 1.1e-24 87.0 0.1 1.3e-24 86.7 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EAQ88831.1 - 8.7e-19 68.0 0.0 1.1e-18 67.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EAQ88831.1 - 1.2e-12 48.2 0.1 1.5e-12 47.8 0.1 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EAQ88831.1 - 1e-05 24.8 0.0 1.4e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.8 EAQ88831.1 - 0.091 12.5 0.1 0.24 11.2 0.1 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Zn_clus PF00172.18 EAQ88832.1 - 8.9e-09 35.3 10.6 1.7e-08 34.4 10.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dabb PF07876.12 EAQ88833.1 - 2.6e-19 69.6 0.5 9e-09 35.9 0.5 2.1 1 1 1 2 2 2 2 Stress responsive A/B Barrel Domain Aldo_ket_red PF00248.21 EAQ88834.1 - 1.2e-39 136.3 0.0 4.5e-37 127.8 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Amidoligase_2 PF12224.8 EAQ88835.1 - 3.8e-10 39.9 0.0 0.00051 19.8 0.0 2.2 2 0 0 2 2 2 2 Putative amidoligase enzyme Thioredoxin PF00085.20 EAQ88836.1 - 2.8e-22 78.6 0.0 4.5e-22 78.0 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EAQ88836.1 - 3.9e-06 27.3 0.2 5.4e-05 23.6 0.2 2.2 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 EAQ88836.1 - 1.1e-05 25.5 0.0 2.6e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like OST3_OST6 PF04756.13 EAQ88836.1 - 1.4e-05 24.6 0.0 1.7e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 EAQ88836.1 - 1.9e-05 24.6 0.0 3e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 EAQ88836.1 - 2.8e-05 24.4 0.0 0.00072 19.8 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin-like Redoxin PF08534.10 EAQ88836.1 - 0.00046 19.9 0.0 0.00067 19.4 0.0 1.3 1 0 0 1 1 1 1 Redoxin Thioredoxin_9 PF14595.6 EAQ88836.1 - 0.025 14.4 0.1 0.053 13.3 0.0 1.7 2 0 0 2 2 2 0 Thioredoxin TraF PF13728.6 EAQ88836.1 - 0.09 12.6 0.1 0.2 11.4 0.1 1.6 1 1 0 1 1 1 0 F plasmid transfer operon protein WD40 PF00400.32 EAQ88837.1 - 2.8e-23 81.7 10.9 5.5e-06 27.0 0.0 7.2 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAQ88837.1 - 5.3e-05 23.4 0.0 1.8 8.9 0.0 3.8 2 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EAQ88837.1 - 0.043 12.8 0.2 1.1 8.1 0.0 2.8 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 EAQ88837.1 - 0.075 12.9 0.0 7.4 6.4 0.0 3.0 3 0 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A Aldo_ket_red PF00248.21 EAQ88838.1 - 5.9e-33 114.3 0.0 3.4e-28 98.7 0.0 2.0 2 0 0 2 2 2 2 Aldo/keto reductase family eRF1_1 PF03463.15 EAQ88839.1 - 3.7e-31 107.8 0.1 7.3e-31 106.8 0.1 1.5 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_3 PF03465.15 EAQ88839.1 - 1.4e-18 67.4 0.0 2.9e-18 66.4 0.0 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_2 PF03464.15 EAQ88839.1 - 9.6e-17 61.5 0.1 1.7e-16 60.7 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 2 BCS1_N PF08740.11 EAQ88840.1 - 1.5e-35 122.9 1.4 1.5e-35 122.9 1.4 2.3 2 1 0 2 2 2 1 BCS1 N terminal AAA PF00004.29 EAQ88840.1 - 1.7e-16 60.8 0.0 5.1e-15 56.1 0.0 2.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EAQ88840.1 - 9.4e-05 22.2 0.0 0.00017 21.4 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 EAQ88840.1 - 0.0069 16.4 0.5 0.016 15.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EAQ88840.1 - 0.0093 16.4 0.0 0.032 14.6 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain IstB_IS21 PF01695.17 EAQ88840.1 - 0.05 13.3 0.0 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 EAQ88840.1 - 0.05 13.2 0.1 0.26 10.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EAQ88840.1 - 0.083 13.4 0.0 0.083 13.4 0.0 2.8 2 1 1 3 3 2 0 AAA domain ATPase PF06745.13 EAQ88840.1 - 0.1 11.9 0.0 0.1 11.9 0.0 2.7 2 1 1 3 3 3 0 KaiC AAA_28 PF13521.6 EAQ88840.1 - 0.31 11.3 3.1 0.4 10.9 0.0 2.6 2 1 0 2 2 2 0 AAA domain AAA_11 PF13086.6 EAQ88840.1 - 0.38 10.5 14.6 0.61 9.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain Borrelia_P83 PF05262.11 EAQ88840.1 - 1.2 7.5 21.9 1.9 6.9 21.9 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein XRN_M PF17846.1 EAQ88840.1 - 4.2 6.2 9.8 6.4 5.6 9.8 1.2 1 0 0 1 1 1 0 Xrn1 helical domain HSP70 PF00012.20 EAQ88840.1 - 7.5 4.6 12.1 11 4.0 12.1 1.2 1 0 0 1 1 1 0 Hsp70 protein ABC2_membrane PF01061.24 EAQ88842.1 - 1.1e-82 276.5 61.2 6.7e-43 146.6 27.5 3.0 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 EAQ88842.1 - 4.1e-38 131.0 0.0 5.3e-18 65.9 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 EAQ88842.1 - 7.2e-33 112.4 0.6 1.8e-26 91.8 0.0 3.3 2 0 0 2 2 2 2 CDR ABC transporter ABC2_membrane_3 PF12698.7 EAQ88842.1 - 1.3e-06 27.8 42.0 3.5e-06 26.4 12.6 3.7 3 1 0 3 3 3 2 ABC-2 family transporter protein AAA_33 PF13671.6 EAQ88842.1 - 2.7e-06 27.6 0.1 0.0015 18.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EAQ88842.1 - 8.2e-06 25.5 1.2 0.014 15.2 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.6 EAQ88842.1 - 2.7e-05 23.9 0.2 0.00037 20.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EAQ88842.1 - 0.00012 22.1 0.3 0.0017 18.3 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase ABC_trans_N PF14510.6 EAQ88842.1 - 0.00041 20.9 0.0 0.0011 19.6 0.0 1.8 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 EAQ88842.1 - 0.00087 19.7 0.3 0.017 15.5 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain SMC_N PF02463.19 EAQ88842.1 - 0.0012 18.3 0.0 4 6.8 0.0 3.8 2 2 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EAQ88842.1 - 0.0016 18.4 0.0 0.17 11.7 0.0 2.8 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 EAQ88842.1 - 0.0016 18.5 0.0 1.5 8.9 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.6 EAQ88842.1 - 0.0049 17.1 0.3 0.67 10.2 0.1 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 EAQ88842.1 - 0.0073 16.2 0.5 1.9 8.4 0.1 2.5 2 0 0 2 2 2 1 NACHT domain AAA_18 PF13238.6 EAQ88842.1 - 0.014 16.0 0.1 0.17 12.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 EAQ88842.1 - 0.015 15.8 0.5 0.49 10.9 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 EAQ88842.1 - 0.038 14.2 0.0 0.11 12.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 EAQ88842.1 - 0.055 13.9 0.4 2.7 8.4 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA PF00004.29 EAQ88842.1 - 0.076 13.4 0.1 18 5.8 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 EAQ88842.1 - 0.15 11.7 2.7 0.18 11.4 0.6 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.22 EAQ88842.1 - 0.16 12.3 0.1 31 5.0 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_30 PF13604.6 EAQ88842.1 - 0.17 11.6 1.9 2.6 7.7 0.5 2.4 2 0 0 2 2 2 0 AAA domain DUF4246 PF14033.6 EAQ88843.1 - 5.3e-160 533.4 0.0 6.3e-160 533.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) WSC PF01822.19 EAQ88844.1 - 9.1e-36 121.9 21.9 7.5e-18 64.5 9.3 2.1 2 0 0 2 2 2 2 WSC domain LysM PF01476.20 EAQ88845.1 - 3.9e-12 46.0 0.0 0.0013 18.7 0.0 4.3 4 0 0 4 4 4 3 LysM domain DUF4471 PF14740.6 EAQ88846.1 - 0.018 14.3 0.0 0.078 12.2 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4471) Sporozoite_P67 PF05642.11 EAQ88846.1 - 0.3 9.1 1.2 0.36 8.9 1.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Zip PF02535.22 EAQ88851.1 - 7.5e-26 91.1 3.7 2e-14 53.5 0.1 2.1 1 1 1 2 2 2 2 ZIP Zinc transporter SelK_SelG PF10961.8 EAQ88851.1 - 0.084 13.5 2.5 0.2 12.3 2.5 1.6 1 0 0 1 1 1 0 Selenoprotein SelK_SelG Glyco_hydro_17 PF00332.18 EAQ88855.1 - 2.6e-08 33.8 0.2 3.7e-08 33.3 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 DUF1180 PF06679.12 EAQ88855.1 - 1.6 9.1 3.8 2.8 8.3 3.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) PBP1_TM PF14812.6 EAQ88856.1 - 0.11 12.9 1.5 0.3 11.5 1.5 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Asp PF00026.23 EAQ88857.1 - 5.7e-56 190.2 0.0 7.1e-56 189.9 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EAQ88857.1 - 1.6e-13 51.3 3.0 1.7e-12 47.9 0.9 3.0 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal ADH_zinc_N_2 PF13602.6 EAQ88858.1 - 6.8e-27 95.1 0.0 1.5e-26 94.0 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EAQ88858.1 - 1.5e-14 54.1 0.8 2.7e-14 53.3 0.8 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 EAQ88858.1 - 0.026 14.0 1.3 0.046 13.2 1.3 1.3 1 0 0 1 1 1 0 short chain dehydrogenase DapB_N PF01113.20 EAQ88858.1 - 0.12 12.5 0.8 0.23 11.6 0.8 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus PTCB-BRCT PF12738.7 EAQ88859.1 - 8.7e-46 153.7 0.2 3.8e-22 78.0 0.0 4.4 4 0 0 4 4 4 3 twin BRCT domain BRCT PF00533.26 EAQ88859.1 - 6.3e-34 116.2 0.0 1e-10 41.8 0.0 4.5 4 0 0 4 4 4 4 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 EAQ88859.1 - 6.9e-17 61.6 0.0 5.1e-05 23.6 0.0 4.3 4 0 0 4 4 4 3 BRCT domain, a BRCA1 C-terminus domain NUDIX PF00293.28 EAQ88859.1 - 1.5e-10 41.2 0.5 3.6e-10 40.0 0.5 1.6 1 0 0 1 1 1 1 NUDIX domain LIG3_BRCT PF16759.5 EAQ88859.1 - 3.7e-09 36.8 0.5 0.00072 19.8 0.1 3.5 3 0 0 3 3 3 2 DNA ligase 3 BRCT domain RTT107_BRCT_5 PF16770.5 EAQ88859.1 - 0.0044 16.9 0.0 0.38 10.6 0.0 3.4 3 0 0 3 3 3 1 Regulator of Ty1 transposition protein 107 BRCT domain NUDIX_4 PF14815.6 EAQ88859.1 - 0.029 14.3 0.2 0.12 12.3 0.0 2.1 2 0 0 2 2 2 0 NUDIX domain BRCT_3 PF18428.1 EAQ88859.1 - 0.049 13.7 0.0 20 5.3 0.0 3.3 3 0 0 3 3 3 0 BRCA1 C Terminus (BRCT) domain Ndc1_Nup PF09531.10 EAQ88859.1 - 0.053 12.2 0.0 0.053 12.2 0.0 3.0 2 1 0 2 2 2 0 Nucleoporin protein Ndc1-Nup AAA PF00004.29 EAQ88863.1 - 6.2e-07 29.9 0.0 1.3e-06 28.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 EAQ88863.1 - 0.00011 22.1 0.0 0.002 18.1 0.0 2.2 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_22 PF13401.6 EAQ88863.1 - 0.0003 21.1 0.0 0.00077 19.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 EAQ88863.1 - 0.001 19.1 0.0 0.002 18.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EAQ88863.1 - 0.0022 18.4 0.1 0.007 16.8 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain ATPase_2 PF01637.18 EAQ88863.1 - 0.013 15.4 0.0 0.024 14.6 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 EAQ88863.1 - 0.051 14.0 0.0 0.12 12.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Serglycin PF04360.12 EAQ88864.1 - 7.9 6.4 11.9 1.3 9.0 7.2 2.0 2 0 0 2 2 2 0 Serglycin ArAE_2_N PF10337.9 EAQ88865.1 - 4e-46 158.0 19.7 3.2e-45 155.0 8.7 3.9 2 1 0 2 2 2 1 Putative ER transporter, 6TM, N-terminal FUSC_2 PF13515.6 EAQ88865.1 - 4.6e-11 42.9 11.4 4.6e-11 42.9 11.4 3.1 2 1 1 3 3 3 1 Fusaric acid resistance protein-like ArAE_2 PF10334.9 EAQ88865.1 - 8.2e-06 25.8 0.0 0.061 13.1 0.0 2.9 3 0 0 3 3 3 2 Aromatic acid exporter family member 2 FA_desaturase PF00487.24 EAQ88866.1 - 2e-26 93.4 28.3 3.7e-26 92.5 28.3 1.4 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 EAQ88866.1 - 3.8e-08 33.6 0.0 7.6e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) Fungal_trans PF04082.18 EAQ88867.1 - 3.3e-13 49.3 0.0 6.1e-13 48.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 EAQ88868.1 - 7.8e-09 35.5 12.2 0.00042 20.6 1.3 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EAQ88868.1 - 2e-07 31.1 6.3 2e-07 31.1 6.3 2.5 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 EAQ88868.1 - 4.6e-05 23.9 11.8 0.032 15.1 1.6 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EAQ88868.1 - 0.0059 16.9 2.9 0.11 12.8 0.3 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EAQ88868.1 - 0.38 11.2 4.4 0.18 12.3 0.8 2.2 2 0 0 2 2 2 0 Zinc-finger of C2H2 type MOSC PF03473.17 EAQ88871.1 - 4.4e-31 107.6 0.0 6.5e-31 107.1 0.0 1.3 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 EAQ88871.1 - 3.4e-13 49.5 0.0 7.7e-13 48.4 0.0 1.6 1 1 0 1 1 1 1 MOSC N-terminal beta barrel domain Abhydrolase_6 PF12697.7 EAQ88872.1 - 1.6e-16 61.6 1.0 2e-16 61.3 1.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EAQ88872.1 - 1.4e-07 31.4 0.0 4.4e-07 29.8 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EAQ88872.1 - 2.6e-06 26.9 0.0 3.7e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Polysacc_deac_1 PF01522.21 EAQ88873.1 - 2.1e-28 98.7 0.0 3.2e-28 98.1 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF202 PF02656.15 EAQ88874.1 - 0.17 12.4 0.3 0.17 12.4 0.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF202) PIG-L PF02585.17 EAQ88875.1 - 1.9e-25 90.0 0.0 2.6e-25 89.6 0.0 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase LSM PF01423.22 EAQ88876.1 - 0.035 13.8 0.1 0.047 13.4 0.1 1.2 1 0 0 1 1 1 0 LSM domain GTP_EFTU PF00009.27 EAQ88877.1 - 1.2e-18 67.4 0.0 2.4e-18 66.4 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 EAQ88877.1 - 1.8e-09 37.8 0.6 1.2e-08 35.2 0.6 2.5 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.17 EAQ88877.1 - 0.00014 22.1 0.0 0.0004 20.7 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 EAQ88877.1 - 0.00026 21.0 0.4 0.00086 19.4 0.4 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EAQ88877.1 - 0.00043 20.2 0.8 0.54 10.2 0.3 2.5 2 0 0 2 2 2 2 RsgA GTPase PduV-EutP PF10662.9 EAQ88877.1 - 0.0075 16.0 0.4 0.63 9.8 0.1 3.1 2 1 1 3 3 3 1 Ethanolamine utilisation - propanediol utilisation Roc PF08477.13 EAQ88877.1 - 0.0077 16.4 0.2 0.12 12.6 0.1 2.5 1 1 1 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 EAQ88877.1 - 0.067 13.2 0.1 0.17 12.0 0.1 1.6 1 0 0 1 1 1 0 Dynamin family LDB19 PF13002.7 EAQ88878.1 - 3.2e-37 128.1 0.2 5.5e-37 127.4 0.2 1.4 1 0 0 1 1 1 1 Arrestin_N terminal like Arrestin_N PF00339.29 EAQ88878.1 - 2.2e-05 24.5 0.0 4.5e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Spo0M PF07070.11 EAQ88878.1 - 0.0039 16.7 0.0 0.0066 16.0 0.0 1.3 1 0 0 1 1 1 1 SpoOM protein SQS_PSY PF00494.19 EAQ88880.1 - 3e-62 210.5 0.0 3.7e-62 210.2 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase SNF2_N PF00176.23 EAQ88881.1 - 2e-74 250.5 0.0 2.7e-74 250.0 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.11 EAQ88881.1 - 3.1e-25 87.9 0.0 5.5e-25 87.1 0.0 1.4 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.31 EAQ88881.1 - 5.6e-16 58.9 0.0 1.2e-15 57.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.25 EAQ88881.1 - 0.00079 19.2 11.2 0.0016 18.3 11.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ERCC3_RAD25_C PF16203.5 EAQ88881.1 - 0.0024 17.1 0.1 0.0047 16.2 0.1 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase zf-C3HC4_2 PF13923.6 EAQ88881.1 - 0.003 17.3 7.3 0.0064 16.3 7.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EAQ88881.1 - 0.0034 17.2 8.8 0.0062 16.4 8.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EAQ88881.1 - 0.0036 17.6 11.8 0.011 16.1 11.8 1.9 1 0 0 1 1 1 1 Ring finger domain ResIII PF04851.15 EAQ88881.1 - 0.0056 16.7 0.0 0.016 15.2 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit zf-RING_UBOX PF13445.6 EAQ88881.1 - 0.13 12.3 10.3 0.28 11.3 10.3 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.6 EAQ88881.1 - 2.4 8.2 10.2 6.2 6.9 10.2 1.8 1 0 0 1 1 1 0 zinc-RING finger domain Helitron_like_N PF14214.6 EAQ88882.1 - 3.7e-36 125.1 0.4 6.9e-36 124.2 0.4 1.4 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.14 EAQ88882.1 - 1.2e-28 100.3 0.0 6.7e-23 81.5 0.0 2.2 2 0 0 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 EAQ88882.1 - 4.7e-11 42.8 0.0 2.1e-10 40.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EAQ88882.1 - 5.5e-06 26.8 0.0 1.1e-05 25.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain Herpes_Helicase PF02689.14 EAQ88882.1 - 0.00043 18.4 0.0 0.00092 17.3 0.0 1.4 2 0 0 2 2 2 1 Helicase UvrD_C_2 PF13538.6 EAQ88882.1 - 0.0029 17.4 0.0 0.0069 16.2 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain DDE_1 PF03184.19 EAQ88883.1 - 4.2e-34 117.7 0.1 3.9e-33 114.5 0.0 2.3 2 1 1 3 3 3 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 EAQ88883.1 - 2.4e-11 43.5 0.1 8.4e-11 41.8 0.1 2.0 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.16 EAQ88883.1 - 9.5e-08 31.7 0.0 1.7e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_23 PF13384.6 EAQ88883.1 - 2.6e-05 23.9 0.0 7.1e-05 22.5 0.0 1.8 1 0 0 1 1 1 1 Homeodomain-like domain DDE_3 PF13358.6 EAQ88883.1 - 0.023 14.5 0.0 0.049 13.4 0.0 1.6 1 0 0 1 1 1 0 DDE superfamily endonuclease HTH_28 PF13518.6 EAQ88883.1 - 0.042 14.0 0.2 0.14 12.3 0.1 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain Helitron_like_N PF14214.6 EAQ88884.1 - 8.8e-17 61.9 0.0 2.2e-16 60.7 0.0 1.6 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus HTH_Tnp_Tc5 PF03221.16 EAQ88884.1 - 0.0018 18.2 0.0 0.0061 16.6 0.0 1.9 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_1 PF03184.19 EAQ88885.1 - 1.8e-33 115.6 0.0 1.1e-32 113.1 0.0 2.1 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 EAQ88885.1 - 4.7e-11 42.5 0.1 1.7e-10 40.8 0.1 2.0 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.16 EAQ88885.1 - 1.6e-07 31.0 0.0 3.3e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_23 PF13384.6 EAQ88885.1 - 4.4e-05 23.1 0.0 0.00014 21.6 0.0 1.9 1 0 0 1 1 1 1 Homeodomain-like domain Collagen_bind_2 PF12904.7 EAQ88885.1 - 0.038 14.0 0.3 9.1 6.3 0.0 2.6 2 0 0 2 2 2 0 Putative collagen-binding domain of a collagenase DDE_3 PF13358.6 EAQ88885.1 - 0.053 13.3 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 DDE superfamily endonuclease HTH_28 PF13518.6 EAQ88885.1 - 0.066 13.3 0.1 0.26 11.4 0.1 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain DUF5399 PF17377.2 EAQ88885.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5399) DDE_1 PF03184.19 EAQ88886.1 - 1.4e-25 90.0 0.0 2.2e-25 89.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 EAQ88886.1 - 0.039 13.7 0.0 0.1 12.3 0.0 1.6 2 0 0 2 2 2 0 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 EAQ88886.1 - 0.15 12.1 0.0 0.43 10.6 0.0 1.7 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain DUF688 PF05097.12 EAQ88887.1 - 0.24 10.5 1.7 0.3 10.2 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF688) DDE_1 PF03184.19 EAQ88888.1 - 9.9e-27 93.7 0.0 1.2e-26 93.4 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 EAQ88888.1 - 0.0019 18.0 0.0 0.015 15.0 0.0 2.0 2 0 0 2 2 2 1 DDE superfamily endonuclease RVT_1 PF00078.27 EAQ88889.1 - 5.5e-38 130.7 0.0 8.6e-38 130.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_1 PF03184.19 EAQ88890.1 - 5.9e-28 97.7 0.0 1.1e-27 96.8 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 EAQ88890.1 - 0.0075 16.0 0.0 0.019 14.7 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease CODH_A_N PF18537.1 EAQ88890.1 - 0.11 12.5 0.1 0.96 9.5 0.1 2.2 2 0 0 2 2 2 0 Carbon monoxide dehydrogenase subunit alpha N-terminal domain ZapB PF06005.12 EAQ88890.1 - 0.14 12.6 1.1 0.27 11.7 1.1 1.4 1 0 0 1 1 1 0 Cell division protein ZapB RT_RNaseH_2 PF17919.1 EAQ88891.1 - 1.2e-23 83.0 0.0 3.8e-23 81.4 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 EAQ88891.1 - 1.4e-17 63.5 0.0 3e-17 62.5 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 EAQ88891.1 - 1.8e-16 60.3 0.0 6.4e-16 58.5 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 EAQ88891.1 - 3.2e-12 46.7 0.0 7.2e-12 45.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 EAQ88891.1 - 1.4e-11 44.3 0.0 3.2e-11 43.2 0.0 1.6 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 EAQ88891.1 - 0.0017 18.6 0.0 0.0038 17.4 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger DUF1421 PF07223.11 EAQ88891.1 - 0.006 16.4 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain (DUF1421) DnaB_2 PF07261.11 EAQ88891.1 - 0.067 12.9 0.0 0.2 11.4 0.0 1.8 1 0 0 1 1 1 0 Replication initiation and membrane attachment Chromo PF00385.24 EAQ88891.1 - 0.15 12.0 0.1 0.35 10.8 0.1 1.6 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain RVP_2 PF08284.11 EAQ88892.1 - 0.25 11.1 0.0 0.4 10.4 0.0 1.2 1 0 0 1 1 1 0 Retroviral aspartyl protease Pneumo_att_G PF05539.11 EAQ88892.1 - 1.6 8.3 10.9 2.1 7.8 10.9 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Not3 PF04065.15 EAQ88893.1 - 0.075 12.5 0.1 0.099 12.1 0.1 1.2 1 0 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component PAPS_reduct PF01507.19 EAQ88894.1 - 0.00014 21.9 0.0 0.00024 21.2 0.0 1.3 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Carb_bind PF10645.9 EAQ88895.1 - 6.8e-22 77.4 8.2 1.5e-21 76.3 8.2 1.6 1 0 0 1 1 1 1 Carbohydrate binding Amb_V_allergen PF03913.13 EAQ88895.1 - 0.047 13.6 1.0 5.2 7.1 0.1 2.6 2 0 0 2 2 2 0 Amb V Allergen CorA PF01544.18 EAQ88896.1 - 2.4e-24 86.2 2.6 2e-19 70.0 0.4 2.4 2 1 0 2 2 2 2 CorA-like Mg2+ transporter protein MULE PF10551.9 EAQ88897.1 - 4.4e-27 94.4 0.1 1.1e-26 93.1 0.1 1.7 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.18 EAQ88897.1 - 0.11 11.4 0.0 0.19 10.5 0.0 1.3 1 0 0 1 1 1 0 Transposase, Mutator family TYA PF01021.19 EAQ88898.1 - 0.02 15.2 0.5 0.027 14.8 0.5 1.4 1 0 0 1 1 1 0 TYA transposon protein SNF2_N PF00176.23 EAQ88899.1 - 4.1e-33 114.6 0.3 1.7e-28 99.3 0.0 3.0 2 1 1 3 3 3 2 SNF2 family N-terminal domain zf-C3HC4 PF00097.25 EAQ88899.1 - 0.00021 21.1 11.6 0.00048 19.9 11.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EAQ88899.1 - 0.00031 20.6 14.4 0.0014 18.6 13.2 2.4 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 EAQ88899.1 - 0.0006 19.9 9.2 0.0014 18.8 9.2 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING ESCRT-II PF05871.12 EAQ88899.1 - 0.0018 18.5 0.5 0.0052 17.0 0.4 1.7 2 0 0 2 2 2 1 ESCRT-II complex subunit zf-C3HC4_3 PF13920.6 EAQ88899.1 - 0.0025 17.6 10.3 0.0051 16.6 10.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.29 EAQ88899.1 - 0.0025 17.6 0.0 0.0064 16.3 0.0 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_UBOX PF13445.6 EAQ88899.1 - 0.0077 16.2 12.3 0.038 14.0 10.5 2.5 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EAQ88899.1 - 0.015 15.1 9.7 0.035 14.0 9.4 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 EAQ88899.1 - 0.41 10.8 10.4 0.078 13.1 6.6 1.8 2 0 0 2 2 1 0 zinc RING finger of MSL2 zf-RING_6 PF14835.6 EAQ88899.1 - 0.65 9.9 5.4 1.6 8.6 5.4 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Prok-RING_4 PF14447.6 EAQ88899.1 - 0.77 9.7 9.7 2 8.4 9.5 1.9 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 EAQ88899.1 - 1.6 9.1 11.0 4.5 7.7 10.1 2.2 1 1 0 1 1 1 0 Ring finger domain Helicase_C PF00271.31 EAQ88900.1 - 0.13 12.6 0.0 0.2 12.0 0.0 1.3 1 0 0 1 1 1 0 Helicase conserved C-terminal domain Nop14 PF04147.12 EAQ88900.1 - 9 4.4 10.4 10 4.2 10.4 1.0 1 0 0 1 1 1 0 Nop14-like family Methyltransf_2 PF00891.18 EAQ88901.1 - 2.2e-22 79.4 0.0 3.2e-22 78.9 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain MTS PF05175.14 EAQ88901.1 - 0.089 12.3 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain DUF4118 PF13493.6 EAQ88901.1 - 0.12 12.2 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4118) DUF924 PF06041.11 EAQ88901.1 - 0.16 12.1 0.1 0.29 11.2 0.1 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF924) TauD PF02668.16 EAQ88902.1 - 3e-59 201.0 0.1 3.7e-59 200.7 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family FMO-like PF00743.19 EAQ88903.1 - 3.5e-34 118.1 0.0 8.3e-16 57.5 0.0 3.2 3 1 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EAQ88903.1 - 3.9e-13 49.3 0.0 1.1e-08 34.7 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EAQ88903.1 - 1.2e-11 44.4 0.5 2.2e-10 40.3 0.5 2.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EAQ88903.1 - 1.9e-11 44.2 4.6 7e-08 32.4 0.1 3.8 4 0 0 4 4 4 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 EAQ88903.1 - 3.6e-08 32.9 3.0 6.5e-07 28.8 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 EAQ88903.1 - 6e-08 32.8 1.2 4.7e-07 30.0 0.1 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EAQ88903.1 - 6.6e-08 32.7 10.6 3.8e-05 23.7 0.4 4.1 4 0 0 4 4 4 2 FAD-NAD(P)-binding Amino_oxidase PF01593.24 EAQ88903.1 - 2.6e-06 27.0 0.1 0.011 15.1 0.1 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 EAQ88903.1 - 0.0003 20.2 0.6 0.0009 18.7 0.3 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 EAQ88903.1 - 0.0024 17.1 1.3 0.0024 17.1 1.3 1.8 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 EAQ88903.1 - 0.0046 15.7 1.2 0.013 14.2 1.4 1.6 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 EAQ88903.1 - 0.0089 15.2 1.5 0.0089 15.2 1.5 2.2 3 0 0 3 3 3 1 FAD binding domain GIDA PF01134.22 EAQ88903.1 - 0.01 14.9 0.1 0.068 12.2 0.1 2.2 3 0 0 3 3 3 0 Glucose inhibited division protein A Shikimate_DH PF01488.20 EAQ88903.1 - 0.015 15.4 0.3 0.11 12.6 0.1 2.1 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 EAQ88903.1 - 0.026 13.8 0.7 0.071 12.3 0.7 1.7 1 0 0 1 1 1 0 FAD binding domain NAD_binding_7 PF13241.6 EAQ88903.1 - 0.085 13.3 0.2 11 6.5 0.0 2.6 2 0 0 2 2 2 0 Putative NAD(P)-binding 3HCDH_N PF02737.18 EAQ88903.1 - 0.097 12.5 0.8 0.16 11.8 0.8 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.27 EAQ88903.1 - 0.11 13.1 9.8 0.16 12.6 0.6 3.2 4 0 0 4 4 3 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EAQ88903.1 - 7.1 5.8 7.5 3.1 7.0 0.8 2.9 2 1 1 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain DUF2293 PF10056.9 EAQ88904.1 - 2.4e-30 104.6 0.4 5.6e-30 103.4 0.4 1.7 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2293) DUF2505 PF10698.9 EAQ88904.1 - 0.088 12.9 1.1 0.18 11.9 0.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2505) Helicase_C_3 PF13625.6 EAQ88904.1 - 0.11 12.6 0.2 0.51 10.5 0.0 2.0 1 1 1 2 2 2 0 Helicase conserved C-terminal domain Scytalone_dh PF02982.14 EAQ88905.1 - 5.6e-90 299.3 0.4 6.4e-90 299.1 0.4 1.0 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.6 EAQ88905.1 - 1e-05 25.7 0.1 1.8e-05 24.8 0.1 1.4 1 1 0 1 1 1 1 SnoaL-like domain MDM10 PF12519.8 EAQ88906.1 - 2.1e-123 412.7 2.5 2.2e-102 343.3 2.1 3.0 1 1 1 2 2 2 2 Mitochondrial distribution and morphology protein 10 Zip PF02535.22 EAQ88907.1 - 4.5e-58 197.1 6.0 5.4e-58 196.8 6.0 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter PIG-P PF08510.12 EAQ88907.1 - 0.13 12.2 0.1 0.32 10.9 0.0 1.8 2 0 0 2 2 2 0 PIG-P Ank_5 PF13857.6 EAQ88908.1 - 4.4e-09 36.4 0.3 1.5e-08 34.8 0.1 1.9 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAQ88908.1 - 1.5e-08 35.1 0.0 2.5e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAQ88908.1 - 5.2e-05 23.3 0.1 0.0005 20.3 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 EAQ88908.1 - 0.0013 19.1 1.0 0.0036 17.7 0.1 2.1 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 EAQ88908.1 - 0.007 16.9 0.1 0.17 12.5 0.0 2.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) TetR_C_7 PF14246.6 EAQ88908.1 - 0.098 12.7 0.0 0.74 9.9 0.0 2.2 2 0 0 2 2 2 0 AefR-like transcriptional repressor, C-terminal domain Ribosomal_S19e PF01090.19 EAQ88909.1 - 5.3e-59 197.8 0.5 6e-59 197.7 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Ricin_B_lectin PF00652.22 EAQ88910.1 - 4.1e-12 46.5 0.0 0.00053 20.2 0.0 4.4 2 2 2 4 4 4 4 Ricin-type beta-trefoil lectin domain FIST_C PF10442.9 EAQ88910.1 - 0.019 14.9 0.0 1.1 9.2 0.0 2.5 2 0 0 2 2 2 0 FIST C domain Fe-S_biosyn PF01521.20 EAQ88911.1 - 2e-11 44.0 0.0 4.8e-06 26.7 0.0 2.2 2 0 0 2 2 2 2 Iron-sulphur cluster biosynthesis Ribosomal_L30_N PF08079.12 EAQ88912.1 - 6.5e-29 100.0 15.8 1.1e-28 99.2 15.8 1.4 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 EAQ88912.1 - 4.5e-17 61.7 2.2 4.5e-17 61.7 2.2 2.0 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e FRG1 PF06229.12 EAQ88912.1 - 0.081 12.6 4.5 0.13 11.9 4.5 1.3 1 0 0 1 1 1 0 FRG1-like domain Ribosomal_S11 PF00411.19 EAQ88913.1 - 2.1e-46 156.9 1.4 2.6e-46 156.6 1.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 CBM_25 PF03423.13 EAQ88913.1 - 0.098 12.9 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 Carbohydrate binding domain (family 25) BKACE PF05853.12 EAQ88913.1 - 0.1 11.9 0.2 0.13 11.5 0.2 1.1 1 0 0 1 1 1 0 beta-keto acid cleavage enzyme DUF2252 PF10009.9 EAQ88913.1 - 0.16 11.0 0.0 0.21 10.6 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) zf-RVT PF13966.6 EAQ88914.1 - 0.062 14.0 0.0 0.14 12.9 0.0 1.5 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase eIF-3c_N PF05470.12 EAQ88915.1 - 4.4e-173 576.8 18.5 4.4e-173 576.8 18.5 3.1 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 EAQ88915.1 - 1.1e-13 51.6 0.3 1.1e-12 48.4 0.1 2.5 2 0 0 2 2 2 1 PCI domain Dynactin_p22 PF07426.11 EAQ88915.1 - 0.0024 17.8 1.1 0.01 15.7 1.1 2.1 1 0 0 1 1 1 1 Dynactin subunit p22 BSP_II PF05432.11 EAQ88915.1 - 0.14 11.9 30.0 0.044 13.5 20.1 2.3 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) DASH_Ask1 PF08655.10 EAQ88915.1 - 0.16 11.9 1.0 0.58 10.1 0.1 2.3 2 0 0 2 2 2 0 DASH complex subunit Ask1 PROCN PF08083.11 EAQ88916.1 - 3.4e-233 773.6 10.9 3.4e-233 773.6 10.9 1.6 2 0 0 2 2 2 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 EAQ88916.1 - 3.2e-127 422.8 1.4 5.8e-127 422.0 1.4 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 EAQ88916.1 - 4.4e-88 293.2 2.0 4.4e-88 293.2 2.0 2.5 3 0 0 3 3 3 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 EAQ88916.1 - 6.2e-79 263.2 3.2 6.2e-79 263.2 3.2 1.9 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 EAQ88916.1 - 4.5e-71 237.2 0.1 1.1e-70 235.9 0.1 1.7 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.9 EAQ88916.1 - 1.5e-46 156.7 0.1 4e-46 155.3 0.1 1.8 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.11 EAQ88916.1 - 1.6e-45 154.0 0.3 5e-45 152.4 0.0 2.1 2 0 0 2 2 2 1 PROCT (NUC072) domain Myb_DNA-bind_6 PF13921.6 EAQ88917.1 - 1.5e-14 53.9 0.1 2.6e-07 30.8 0.0 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EAQ88917.1 - 3.8e-13 49.4 0.1 1.2e-05 25.4 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain DUF4085 PF13315.6 EAQ88917.1 - 0.059 13.0 0.0 0.083 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4085) HTH_AsnC-type PF13404.6 EAQ88917.1 - 0.15 11.9 0.1 1 9.2 0.0 2.2 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain SNF2_N PF00176.23 EAQ88918.1 - 9.5e-63 212.0 0.0 1.7e-62 211.2 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EAQ88918.1 - 1.1e-21 77.3 0.0 3.4e-21 75.7 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 EAQ88918.1 - 0.0027 16.9 0.0 0.0059 15.8 0.0 1.6 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ERCC3_RAD25_C PF16203.5 EAQ88918.1 - 0.0034 16.6 0.0 0.0067 15.7 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 EAQ88918.1 - 0.019 15.0 0.0 0.13 12.2 0.0 2.3 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit TFIIF_beta PF02270.15 EAQ88918.1 - 0.037 14.2 0.0 0.087 13.0 0.0 1.6 1 0 0 1 1 1 0 TFIIF, beta subunit HTH domain AAA_13 PF13166.6 EAQ88918.1 - 1.7 7.2 6.7 2.7 6.5 6.7 1.2 1 0 0 1 1 1 0 AAA domain Hemerythrin PF01814.23 EAQ88919.1 - 6.7e-08 33.2 5.6 1.5e-05 25.6 0.1 2.6 2 1 0 2 2 2 2 Hemerythrin HHE cation binding domain zf-RVT PF13966.6 EAQ88920.1 - 0.063 14.0 0.0 0.16 12.7 0.0 1.7 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase Mpv17_PMP22 PF04117.12 EAQ88921.1 - 4.2e-09 36.5 4.3 1.1e-08 35.2 3.6 1.9 1 1 1 2 2 2 1 Mpv17 / PMP22 family EAP30 PF04157.16 EAQ88922.1 - 3.5e-76 255.6 0.1 4.1e-76 255.4 0.1 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family Transgly PF00912.22 EAQ88922.1 - 0.034 13.6 0.0 0.061 12.8 0.0 1.4 1 0 0 1 1 1 0 Transglycosylase AAR2 PF05282.11 EAQ88923.1 - 1e-36 127.1 0.0 2.2e-19 70.1 0.0 2.1 1 1 1 2 2 2 2 AAR2 protein TAF4 PF05236.14 EAQ88924.1 - 0.0075 16.0 1.1 0.0075 16.0 1.1 1.6 2 0 0 2 2 2 1 Transcription initiation factor TFIID component TAF4 family IHABP4_N PF16174.5 EAQ88924.1 - 0.25 11.9 7.5 0.14 12.8 1.6 2.4 2 0 0 2 2 2 0 Intracellular hyaluronan-binding protein 4 N-terminal Gag_p17 PF00540.18 EAQ88924.1 - 1.1 9.2 3.8 0.28 11.2 0.1 1.7 2 0 0 2 2 2 0 gag gene protein p17 (matrix protein) DEAD PF00270.29 EAQ88926.1 - 1.5e-49 168.1 0.0 5.8e-48 163.0 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EAQ88926.1 - 1.7e-32 112.1 0.0 3.8e-32 110.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EAQ88926.1 - 9.8e-06 25.7 0.0 7.8e-05 22.7 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 EAQ88926.1 - 0.00084 18.2 0.0 0.15 10.8 0.0 2.3 2 0 0 2 2 2 2 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 AAA_19 PF13245.6 EAQ88926.1 - 0.0072 16.7 0.0 2 8.8 0.0 2.3 2 0 0 2 2 2 2 AAA domain DUF2443 PF10398.9 EAQ88926.1 - 0.082 13.0 0.2 0.17 12.0 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2443) DUF5335 PF17269.2 EAQ88926.1 - 0.11 12.3 0.2 0.19 11.6 0.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5335) Phos_pyr_kin PF08543.12 EAQ88927.1 - 2.3e-81 272.8 0.9 3.6e-81 272.2 0.9 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.16 EAQ88927.1 - 1.3e-34 119.9 0.1 7.3e-20 71.7 0.1 2.2 1 1 1 2 2 2 2 TENA/THI-4/PQQC family PfkB PF00294.24 EAQ88927.1 - 0.001 18.5 0.8 0.12 11.7 0.0 2.3 2 0 0 2 2 2 2 pfkB family carbohydrate kinase HK PF02110.15 EAQ88927.1 - 0.053 12.9 3.3 0.14 11.6 0.1 2.5 3 0 0 3 3 3 0 Hydroxyethylthiazole kinase family RICTOR_N PF14664.6 EAQ88928.1 - 1.3e-108 363.4 2.0 1.2e-82 277.9 0.0 3.4 3 1 1 4 4 4 2 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.6 EAQ88928.1 - 5.7e-38 128.9 0.1 4.4e-36 122.8 0.0 3.8 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.6 EAQ88928.1 - 5.9e-38 129.6 0.1 2.1e-35 121.4 0.0 3.3 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.6 EAQ88928.1 - 2.6e-29 101.3 0.4 4.8e-28 97.2 0.1 3.3 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.16 EAQ88928.1 - 1.1e-14 54.3 8.4 3.6e-14 52.6 8.4 1.9 1 0 0 1 1 1 1 Hr1 repeat Arm PF00514.23 EAQ88928.1 - 0.29 11.3 1.5 5 7.3 0.0 3.3 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat zf-C4H2 PF10146.9 EAQ88928.1 - 1.9 8.8 11.3 1.4 9.1 4.6 2.7 3 0 0 3 3 3 0 Zinc finger-containing protein Uricase PF01014.18 EAQ88929.1 - 9.1e-79 262.1 0.2 6e-42 143.0 0.7 2.0 2 0 0 2 2 2 2 Uricase Ribosomal_L13 PF00572.18 EAQ88930.1 - 3.5e-40 137.1 0.0 6.1e-40 136.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L13 HMA PF00403.26 EAQ88931.1 - 6.2e-15 55.4 0.1 9.8e-15 54.8 0.1 1.3 1 0 0 1 1 1 1 Heavy-metal-associated domain Sod_Cu PF00080.20 EAQ88931.1 - 1.3e-08 35.1 0.0 2.4e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) TPR_1 PF00515.28 EAQ88933.1 - 3.4e-16 58.3 9.0 4.5e-08 32.6 0.1 4.8 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.17 EAQ88933.1 - 5.2e-14 51.2 4.9 8.5e-06 25.5 0.0 4.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 EAQ88933.1 - 2.2e-11 43.9 0.5 8e-07 29.3 0.1 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 EAQ88933.1 - 2.1e-10 39.9 3.6 1.3e-05 25.0 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 EAQ88933.1 - 9.6e-09 34.8 0.9 1.3e-05 24.8 0.3 3.8 2 1 1 3 3 3 1 TPR repeat PB1 PF00564.24 EAQ88933.1 - 5.6e-07 29.4 0.2 1e-06 28.6 0.2 1.4 1 0 0 1 1 1 1 PB1 domain TPR_6 PF13174.6 EAQ88933.1 - 5.6e-07 29.8 1.4 0.15 12.8 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 EAQ88933.1 - 1.2e-06 28.5 0.1 0.007 16.5 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 EAQ88933.1 - 2.2e-05 24.1 0.4 0.0045 16.9 0.1 3.3 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 EAQ88933.1 - 0.00026 21.1 0.2 0.3 11.6 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 EAQ88933.1 - 0.00033 21.2 0.2 0.015 16.0 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 EAQ88933.1 - 0.0088 16.8 0.0 0.27 12.1 0.0 2.9 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 EAQ88933.1 - 0.2 11.6 2.5 1.6 8.7 0.1 3.3 3 1 1 4 4 3 0 Tetratricopeptide repeat FAR1 PF03101.15 EAQ88934.1 - 2.1e-05 25.1 0.5 2.1e-05 25.1 0.5 1.8 2 0 0 2 2 2 1 FAR1 DNA-binding domain HSBP1 PF06825.12 EAQ88934.1 - 0.0038 17.1 0.0 0.0087 15.9 0.0 1.6 1 0 0 1 1 1 1 Heat shock factor binding protein 1 AFT PF08731.11 EAQ88934.1 - 0.034 14.6 0.4 0.034 14.6 0.4 2.3 2 0 0 2 2 2 0 Transcription factor AFT MDM10 PF12519.8 EAQ88934.1 - 0.12 11.3 1.8 0.18 10.6 1.8 1.2 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 SelP_N PF04592.14 EAQ88934.1 - 0.22 10.9 13.7 0.39 10.1 13.7 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Macoilin PF09726.9 EAQ88934.1 - 0.56 8.7 5.5 0.75 8.3 5.5 1.2 1 0 0 1 1 1 0 Macoilin family DUF16 PF01519.16 EAQ88934.1 - 0.91 10.0 7.5 1.1 9.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function DUF16 Neur_chan_memb PF02932.16 EAQ88934.1 - 0.92 9.5 4.0 1.9 8.5 4.0 1.6 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Presenilin PF01080.17 EAQ88934.1 - 5.7 5.6 5.3 7.7 5.2 5.3 1.2 1 0 0 1 1 1 0 Presenilin DUF4763 PF15960.5 EAQ88935.1 - 4.1e-05 23.0 1.1 4.8e-05 22.8 1.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4763) ABATE PF07336.11 EAQ88935.1 - 0.055 14.1 0.5 0.065 13.9 0.5 1.4 1 1 0 1 1 1 0 Putative stress-induced transcription regulator Mis14 PF08641.12 EAQ88935.1 - 0.18 12.1 2.0 0.77 10.1 0.1 2.2 1 1 2 3 3 3 0 Kinetochore protein Mis14 like Ribosomal_L34e PF01199.18 EAQ88936.1 - 3.1e-43 146.0 1.7 4.4e-43 145.5 1.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L34e Vps36-NZF-N PF16988.5 EAQ88936.1 - 0.036 13.5 0.0 0.074 12.5 0.0 1.8 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain FhuF_C PF11575.8 EAQ88936.1 - 0.35 10.8 4.4 1.7 8.7 0.3 2.6 2 0 0 2 2 2 0 FhuF 2Fe-2S C-terminal domain DUF498 PF04430.14 EAQ88937.1 - 7.7e-20 71.0 0.0 1.1e-19 70.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) CMAS PF02353.20 EAQ88938.1 - 5.9e-62 209.4 0.1 7.3e-62 209.1 0.1 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 EAQ88938.1 - 7.3e-09 35.7 0.0 1.4e-08 34.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EAQ88938.1 - 1e-08 35.7 0.0 2.2e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAQ88938.1 - 4.9e-08 33.6 0.0 9.9e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 EAQ88938.1 - 0.024 14.2 0.0 0.039 13.5 0.0 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_32 PF13679.6 EAQ88938.1 - 0.069 13.1 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 EAQ88938.1 - 0.16 11.7 0.1 0.29 10.9 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.19 EAQ88938.1 - 0.18 11.9 0.1 0.66 10.1 0.0 1.9 1 1 1 2 2 2 0 FtsJ-like methyltransferase MTS PF05175.14 EAQ88938.1 - 0.23 11.0 0.1 0.39 10.2 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Alpha-amylase PF00128.24 EAQ88939.1 - 4.9e-105 351.8 0.1 7.1e-105 351.3 0.1 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Cellulase PF00150.18 EAQ88939.1 - 0.0024 17.3 0.0 0.0056 16.2 0.0 1.5 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Malt_amylase_C PF16657.5 EAQ88939.1 - 0.0027 17.8 0.0 0.0065 16.6 0.0 1.6 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain hDGE_amylase PF14701.6 EAQ88939.1 - 0.053 12.6 0.0 0.09 11.9 0.0 1.3 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain Glyco_hydro_114 PF03537.13 EAQ88939.1 - 0.12 11.7 0.2 0.4 9.9 0.1 1.9 2 0 0 2 2 2 0 Glycoside-hydrolase family GH114 Glyco_hydro_42C PF08533.10 EAQ88939.1 - 0.12 12.1 0.2 0.97 9.2 0.0 2.5 2 0 0 2 2 2 0 Beta-galactosidase C-terminal domain G-patch_2 PF12656.7 EAQ88940.1 - 1.8e-11 44.0 0.1 1.1e-10 41.4 0.0 2.5 2 0 0 2 2 2 1 G-patch domain Pneumo_att_G PF05539.11 EAQ88940.1 - 0.51 9.9 7.1 0.74 9.3 7.1 1.3 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G HSA PF07529.13 EAQ88941.1 - 2.8e-12 46.8 0.3 2.8e-12 46.8 0.3 4.7 5 0 0 5 5 5 1 HSA Myb_DNA-bind_6 PF13921.6 EAQ88941.1 - 5.4e-12 45.8 0.2 1.7e-11 44.2 0.2 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EAQ88941.1 - 6e-05 23.1 0.8 0.00014 22.0 0.8 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain SUIM_assoc PF16619.5 EAQ88941.1 - 0.4 10.8 0.0 0.4 10.8 0.0 8.3 3 2 2 5 5 5 0 Unstructured region C-term to UIM in Ataxin3 LRV PF01816.17 EAQ88941.1 - 1 9.9 3.2 1.2 9.6 0.1 3.0 2 0 0 2 2 2 0 Leucine rich repeat variant WD40 PF00400.32 EAQ88942.1 - 1.8e-10 41.2 0.0 3.3 8.7 0.0 6.3 7 0 0 7 7 7 4 WD domain, G-beta repeat Ge1_WD40 PF16529.5 EAQ88942.1 - 0.12 11.3 0.0 4 6.3 0.0 2.5 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF1174 PF06671.11 EAQ88942.1 - 1 9.1 5.2 2.2 8.1 5.2 1.5 1 0 0 1 1 1 0 Repeat of unknown function (DUF1174) INSIG PF07281.12 EAQ88943.1 - 3.6e-90 301.2 0.1 4.7e-90 300.9 0.1 1.1 1 0 0 1 1 1 1 Insulin-induced protein (INSIG) bHLH-MYC_N PF14215.6 EAQ88943.1 - 0.058 13.7 0.0 0.086 13.1 0.0 1.3 1 0 0 1 1 1 0 bHLH-MYC and R2R3-MYB transcription factors N-terminal zf-C3HC4_2 PF13923.6 EAQ88944.1 - 2.3e-12 46.6 16.0 6.2e-08 32.4 6.6 2.9 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EAQ88944.1 - 1.1e-10 41.5 19.8 3.1e-06 27.2 3.8 2.9 2 0 0 2 2 2 2 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 EAQ88944.1 - 2.4e-10 40.3 19.8 5.2e-06 26.4 5.0 2.8 2 0 0 2 2 2 2 RING-type zinc-finger zf-RING_2 PF13639.6 EAQ88944.1 - 1.5e-09 38.1 21.1 8.1e-06 26.1 7.1 2.8 2 0 0 2 2 2 2 Ring finger domain zf-RING_5 PF14634.6 EAQ88944.1 - 2.7e-09 36.8 17.1 4.9e-06 26.4 6.2 2.8 2 0 0 2 2 2 2 zinc-RING finger domain LON_substr_bdg PF02190.16 EAQ88944.1 - 1.6e-08 34.7 0.0 2.8e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain zf-C3HC4 PF00097.25 EAQ88944.1 - 1.8e-08 34.1 16.5 1.7e-05 24.6 7.8 2.8 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EAQ88944.1 - 1e-07 31.7 14.4 1.4e-05 24.9 5.7 2.6 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EAQ88944.1 - 0.00012 21.9 15.0 0.00018 21.3 5.0 2.8 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 EAQ88944.1 - 0.0051 16.6 1.9 0.0051 16.6 1.9 3.1 3 0 0 3 3 3 1 RING/Ubox like zinc-binding domain Ribosomal_L37e PF01907.19 EAQ88944.1 - 9.3 6.5 7.0 33 4.8 0.0 3.1 3 0 0 3 3 3 0 Ribosomal protein L37e zf-rbx1 PF12678.7 EAQ88944.1 - 9.3 6.6 16.4 0.28 11.5 5.8 3.1 3 1 0 3 3 3 0 RING-H2 zinc finger domain efThoc1 PF11957.8 EAQ88945.1 - 1.5e-114 383.4 8.4 1.9e-75 254.4 2.6 2.1 1 1 1 2 2 2 2 THO complex subunit 1 transcription elongation factor Guanylate_kin PF00625.21 EAQ88945.1 - 6.9e-20 71.5 0.1 8e-19 68.0 0.0 2.3 2 0 0 2 2 2 1 Guanylate kinase DUF4988 PF16378.5 EAQ88945.1 - 0.037 13.7 0.0 0.073 12.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function Aquarius_N PF16399.5 EAQ88946.1 - 0 1040.9 0.2 1.3e-222 741.2 0.2 2.1 1 1 1 2 2 2 2 Intron-binding protein aquarius N-terminus AAA_12 PF13087.6 EAQ88946.1 - 1e-26 93.8 0.0 1.6e-26 93.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAQ88946.1 - 8.2e-21 75.0 0.0 3.7e-20 72.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EAQ88946.1 - 2.2e-08 34.1 0.0 0.00063 19.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain ResIII PF04851.15 EAQ88946.1 - 1.1e-05 25.6 0.0 2.2e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 EAQ88946.1 - 3e-05 24.4 0.0 6.6e-05 23.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EAQ88946.1 - 0.00041 20.8 0.0 0.0019 18.6 0.0 2.2 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 EAQ88946.1 - 0.002 18.5 0.0 0.0052 17.2 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.18 EAQ88946.1 - 0.0052 16.6 0.2 0.27 10.9 0.0 2.8 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase DnaB_C PF03796.15 EAQ88946.1 - 0.014 14.7 0.0 0.03 13.7 0.0 1.5 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain UvrD_C_2 PF13538.6 EAQ88946.1 - 0.016 15.0 1.0 0.075 12.9 0.2 2.3 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain AAA_22 PF13401.6 EAQ88946.1 - 0.023 14.9 0.1 0.15 12.3 0.0 2.2 1 1 1 2 2 2 0 AAA domain DUF2075 PF09848.9 EAQ88946.1 - 0.082 12.1 1.3 0.11 11.7 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_33 PF13671.6 EAQ88946.1 - 0.11 12.6 0.0 0.74 10.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain PIF1 PF05970.14 EAQ88946.1 - 0.16 11.1 0.0 11 5.1 0.0 2.3 2 0 0 2 2 2 0 PIF1-like helicase MIF4G PF02854.19 EAQ88948.1 - 6.7e-42 143.5 0.1 6.6e-41 140.3 0.1 2.2 1 1 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.8 EAQ88948.1 - 2.4e-22 78.9 0.5 6.1e-22 77.6 0.5 1.8 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 DNA_pol_B PF00136.21 EAQ88949.1 - 1.5e-113 379.9 0.0 2.6e-113 379.2 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.10 EAQ88949.1 - 3.2e-68 229.1 0.0 5.7e-68 228.3 0.0 1.4 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.19 EAQ88949.1 - 1.7e-41 142.5 0.0 2.9e-41 141.7 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.8 EAQ88949.1 - 3e-24 84.9 10.3 3e-24 84.9 10.3 2.7 2 0 0 2 2 2 1 DNA polymerase alpha subunit p180 N terminal DNA_pol_B_2 PF03175.13 EAQ88949.1 - 0.017 14.0 0.0 0.043 12.7 0.0 1.6 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral TF_Zn_Ribbon PF08271.12 EAQ88949.1 - 0.12 11.9 0.0 0.36 10.4 0.0 1.9 1 0 0 1 1 1 0 TFIIB zinc-binding PPR_2 PF13041.6 EAQ88950.1 - 1.2e-24 86.2 1.3 1.7e-15 57.0 0.0 5.3 6 0 0 6 6 6 2 PPR repeat family PPR_3 PF13812.6 EAQ88950.1 - 4.2e-07 30.0 0.3 0.0099 15.9 0.1 2.8 2 0 0 2 2 2 2 Pentatricopeptide repeat domain PPR_long PF17177.4 EAQ88950.1 - 4.7e-07 29.4 0.2 1.4e-06 27.9 0.1 1.8 2 0 0 2 2 2 1 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 EAQ88950.1 - 6.6e-07 29.2 1.9 0.0031 17.6 0.0 5.3 5 1 0 5 5 5 1 PPR repeat PPR_1 PF12854.7 EAQ88950.1 - 0.0032 17.2 1.6 4.5 7.1 0.0 5.1 7 0 0 7 7 7 1 PPR repeat ELYS PF13934.6 EAQ88950.1 - 0.23 11.4 1.3 1.4 8.9 0.1 2.6 3 0 0 3 3 3 0 Nuclear pore complex assembly RRM_1 PF00076.22 EAQ88952.1 - 1.4e-05 24.8 0.0 2.2e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Btz PF09405.10 EAQ88952.1 - 0.0065 16.7 0.7 0.0065 16.7 0.7 1.7 2 0 0 2 2 2 1 CASC3/Barentsz eIF4AIII binding Pkinase PF00069.25 EAQ88953.1 - 1.6e-47 162.1 0.2 8.5e-47 159.7 0.2 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ88953.1 - 4.1e-21 75.4 0.0 8.8e-21 74.3 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EAQ88953.1 - 0.00036 20.5 0.1 0.00036 20.5 0.1 2.6 2 1 1 3 3 3 1 Phosphotransferase enzyme family RIO1 PF01163.22 EAQ88953.1 - 0.0024 17.5 0.3 0.0074 15.9 0.3 1.7 1 1 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 EAQ88953.1 - 0.22 11.1 1.7 0.33 10.5 0.1 2.1 2 0 0 2 2 2 0 Choline/ethanolamine kinase Band_3_cyto PF07565.13 EAQ88953.1 - 0.54 10.0 2.5 1.4 8.6 2.5 1.7 1 0 0 1 1 1 0 Band 3 cytoplasmic domain RRM_1 PF00076.22 EAQ88954.1 - 8e-48 160.1 0.0 4.1e-21 74.6 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EAQ88954.1 - 4.2e-05 23.3 0.0 0.014 15.2 0.0 3.2 3 0 0 3 3 3 1 Occluded RNA-recognition motif RRM_5 PF13893.6 EAQ88954.1 - 6.9e-05 22.4 0.0 0.27 10.9 0.0 3.1 1 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EAQ88954.1 - 0.0033 17.4 0.0 9.1 6.4 0.0 3.5 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RNA_bind PF08675.11 EAQ88954.1 - 0.023 14.7 0.1 5.9 7.0 0.0 2.6 2 0 0 2 2 2 0 RNA binding domain Acetyltransf_10 PF13673.7 EAQ88954.1 - 0.048 13.6 0.0 0.095 12.6 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain RRM_8 PF11835.8 EAQ88954.1 - 0.051 13.8 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 RRM-like domain RRM_7 PF16367.5 EAQ88954.1 - 0.088 12.9 0.0 0.93 9.7 0.0 2.6 2 0 0 2 2 2 0 RNA recognition motif Med2 PF11214.8 EAQ88955.1 - 0.17 12.0 0.0 0.31 11.2 0.0 1.4 1 0 0 1 1 1 0 Mediator complex subunit 2 Cellulase PF00150.18 EAQ88956.1 - 1.2e-17 64.3 0.3 2.5e-17 63.2 0.3 1.5 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) GXWXG PF14231.6 EAQ88956.1 - 4 7.6 6.5 6.4 6.9 0.1 3.0 4 0 0 4 4 4 0 GXWXG protein PH PF00169.29 EAQ88957.1 - 8.4e-23 80.9 2.7 4.2e-14 52.9 0.1 2.2 2 0 0 2 2 2 2 PH domain PH_9 PF15410.6 EAQ88957.1 - 2.3e-09 37.7 1.9 1.6e-06 28.5 0.5 3.4 2 2 0 2 2 2 2 Pleckstrin homology domain PH_11 PF15413.6 EAQ88957.1 - 1.8e-08 34.8 7.0 0.00026 21.4 0.6 3.1 2 1 0 2 2 2 2 Pleckstrin homology domain PH_8 PF15409.6 EAQ88957.1 - 0.0046 17.2 0.1 0.0091 16.3 0.1 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain APH PF01636.23 EAQ88958.1 - 4.5e-09 36.6 0.0 5.9e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EAQ88958.1 - 2.3e-07 30.6 0.0 3.9e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.20 EAQ88958.1 - 6e-05 22.5 0.0 9.3e-05 21.9 0.0 1.4 1 1 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.11 EAQ88958.1 - 0.04 12.8 0.0 0.06 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Fructosamin_kin PF03881.14 EAQ88958.1 - 0.069 12.3 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 Fructosamine kinase CTU2 PF10288.9 EAQ88959.1 - 2.8e-13 50.1 0.0 1.4e-11 44.6 0.0 2.6 1 1 1 2 2 2 1 Cytoplasmic tRNA 2-thiolation protein 2 ATP_bind_3 PF01171.20 EAQ88959.1 - 0.0095 15.7 0.2 1.1 9.0 0.0 2.3 2 0 0 2 2 2 2 PP-loop family PAPS_reduct PF01507.19 EAQ88959.1 - 0.15 12.1 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family Mito_carr PF00153.27 EAQ88960.1 - 4.1e-55 183.7 0.8 5.2e-19 68.0 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein WD40 PF00400.32 EAQ88961.1 - 5.6e-13 49.2 6.0 1.5e-06 28.8 0.1 5.1 5 0 0 5 5 5 2 WD domain, G-beta repeat Nup160 PF11715.8 EAQ88961.1 - 0.082 11.5 0.0 0.1 11.2 0.0 1.1 1 0 0 1 1 1 0 Nucleoporin Nup120/160 SRP9-21 PF05486.12 EAQ88962.1 - 4.6e-34 116.7 5.7 2.8e-33 114.2 5.7 1.9 1 1 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) Ribonuc_red_sm PF00268.21 EAQ88963.1 - 6.8e-121 403.0 1.6 8.5e-121 402.7 1.6 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain DUF4112 PF13430.6 EAQ88964.1 - 9e-34 115.9 0.1 1.1e-33 115.6 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) NUDIX PF00293.28 EAQ88965.1 - 1.3e-15 57.6 0.1 2.4e-15 56.7 0.1 1.4 1 0 0 1 1 1 1 NUDIX domain DCP2 PF05026.13 EAQ88965.1 - 0.0017 18.6 0.1 0.0037 17.5 0.1 1.6 1 0 0 1 1 1 1 Dcp2, box A domain ParB PF08775.10 EAQ88965.1 - 0.036 14.5 0.1 0.13 12.8 0.1 1.9 2 0 0 2 2 2 0 ParB family MGC-24 PF05283.11 EAQ88967.1 - 0.007 16.8 0.4 0.014 15.9 0.4 1.4 1 0 0 1 1 1 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin Pkinase PF00069.25 EAQ88968.1 - 3.4e-60 203.7 0.0 4.7e-60 203.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ88968.1 - 9e-29 100.5 0.0 1.5e-28 99.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAQ88968.1 - 0.00024 20.5 0.0 0.00048 19.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EAQ88968.1 - 0.00097 18.5 0.0 0.0017 17.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EAQ88968.1 - 0.015 15.2 0.1 0.015 15.2 0.1 2.4 3 0 0 3 3 3 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EAQ88968.1 - 0.056 12.4 0.0 0.079 11.9 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain LCD1 PF09798.9 EAQ88968.1 - 0.42 9.1 4.0 0.78 8.2 1.7 1.9 2 0 0 2 2 2 0 DNA damage checkpoint protein WD40 PF00400.32 EAQ88969.1 - 6.5e-69 226.2 9.2 2.4e-12 47.2 0.1 7.3 6 1 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAQ88969.1 - 3.8e-29 100.8 0.5 8.6e-05 22.8 0.0 6.0 2 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EAQ88969.1 - 2e-17 63.1 4.1 0.06 12.3 0.0 6.4 3 1 4 7 7 7 5 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 EAQ88969.1 - 1.4e-13 50.4 0.1 1.3 9.0 0.0 5.7 5 0 0 5 5 5 5 WD40-like Beta Propeller Repeat NACHT PF05729.12 EAQ88969.1 - 2.3e-09 37.4 0.0 4.6e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EAQ88969.1 - 9.2e-08 32.7 2.3 3.6e-07 30.7 0.1 2.9 3 0 0 3 3 3 1 AAA ATPase domain Ret2_MD PF18528.1 EAQ88969.1 - 3.1e-06 27.5 0.0 12 6.3 0.0 5.6 2 2 2 5 5 5 0 RNA editing 3' terminal uridylyl transferase 2 middle domain Tli4_C PF18426.1 EAQ88969.1 - 5.1e-05 23.6 0.1 35 4.6 0.0 5.2 5 0 0 5 5 5 0 Tle cognate immunity protein 4 C-terminal domain WD40_like PF17005.5 EAQ88969.1 - 0.00013 21.4 0.0 2.8 7.2 0.0 3.9 1 1 4 5 5 5 2 WD40-like domain DUF4784 PF16023.5 EAQ88969.1 - 0.0002 20.5 0.1 11 4.9 0.0 4.6 1 1 4 5 5 5 0 Domain of unknown function (DUF4784) Proteasome_A_N PF10584.9 EAQ88969.1 - 0.00083 19.0 0.3 1.4e+02 2.3 0.0 5.5 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature Frtz PF11768.8 EAQ88969.1 - 0.00098 17.6 0.0 7.4 4.8 0.0 3.9 1 1 3 4 4 4 1 WD repeat-containing and planar cell polarity effector protein Fritz NYD-SP28_assoc PF14775.6 EAQ88969.1 - 0.0011 19.1 4.9 1.2e+02 2.9 0.0 6.4 6 0 0 6 6 6 0 Sperm tail C-terminal domain IKI3 PF04762.12 EAQ88969.1 - 0.0022 16.1 0.1 0.93 7.4 0.1 2.6 1 1 1 2 2 2 2 IKI3 family DUF815 PF05673.13 EAQ88969.1 - 0.018 14.2 0.0 0.039 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) CbiA PF01656.23 EAQ88969.1 - 0.038 14.0 0.8 0.74 9.9 0.2 2.6 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_30 PF13604.6 EAQ88969.1 - 0.047 13.4 0.0 0.39 10.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain SurE PF01975.17 EAQ88969.1 - 0.065 13.0 1.6 27 4.5 0.0 3.9 1 1 2 4 4 4 0 Survival protein SurE NB-ARC PF00931.22 EAQ88969.1 - 0.079 12.1 0.0 0.29 10.3 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain YopE_N PF09020.10 EAQ88969.1 - 0.095 13.0 0.3 32 4.8 0.1 3.1 1 1 2 3 3 3 0 YopE, N terminal KAP_NTPase PF07693.14 EAQ88969.1 - 0.12 11.5 0.2 0.26 10.5 0.2 1.5 1 0 0 1 1 1 0 KAP family P-loop domain DUF746 PF05344.11 EAQ88969.1 - 0.24 11.3 2.7 2.1 8.2 0.1 4.0 5 0 0 5 5 5 0 Domain of Unknown Function (DUF746) DUF4596 PF15363.6 EAQ88969.1 - 0.93 9.8 6.2 21 5.4 0.1 4.5 5 0 0 5 5 4 0 Domain of unknown function (DUF4596) DUF1899 PF08953.11 EAQ88971.1 - 1.9e-34 117.3 0.0 3.7e-34 116.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 EAQ88971.1 - 1.9e-19 69.3 0.2 4.6e-19 68.0 0.2 1.7 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 EAQ88971.1 - 6.7e-17 61.6 7.8 0.00019 22.2 0.0 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAQ88971.1 - 8.6e-09 35.6 0.3 0.00046 20.4 0.1 4.0 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EAQ88971.1 - 0.00021 20.4 0.0 0.028 13.4 0.0 2.2 1 1 1 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 EAQ88971.1 - 0.00096 19.1 0.0 0.0094 15.9 0.0 2.1 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 EAQ88971.1 - 0.0018 17.0 0.7 0.041 12.5 0.2 2.2 1 1 1 2 2 2 1 Nucleoporin Nup120/160 SlyX PF04102.12 EAQ88971.1 - 0.2 12.3 8.9 0.15 12.7 4.1 2.4 2 0 0 2 2 2 0 SlyX DUF16 PF01519.16 EAQ88971.1 - 0.39 11.2 3.7 0.83 10.2 3.7 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF16 Paramyx_P_V_C PF03210.13 EAQ88971.1 - 2.1 8.1 5.0 0.35 10.7 0.7 1.9 2 0 0 2 2 2 0 Paramyxovirus P/V phosphoprotein C-terminal Glyco_transf_22 PF03901.17 EAQ88972.1 - 1e-74 252.3 20.5 1.3e-74 251.9 20.5 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family DUF4010 PF13194.6 EAQ88972.1 - 0.1 12.3 8.3 0.034 13.8 0.9 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4010) Aminotran_3 PF00202.21 EAQ88973.1 - 1.1e-92 310.8 0.0 1.1e-76 258.2 0.0 2.0 1 1 1 2 2 2 2 Aminotransferase class-III Beta_elim_lyase PF01212.21 EAQ88973.1 - 0.042 13.1 0.0 0.089 12.1 0.0 1.4 1 1 0 1 1 1 0 Beta-eliminating lyase DUF3543 PF12063.8 EAQ88974.1 - 1.9e-93 312.5 0.6 2.8e-93 311.9 0.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase PF00069.25 EAQ88974.1 - 2.2e-60 204.2 0.0 4e-60 203.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ88974.1 - 1.2e-39 136.2 0.0 2.7e-39 135.0 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase ABC1 PF03109.16 EAQ88974.1 - 0.05 13.8 0.4 0.51 10.5 0.0 2.7 3 0 0 3 3 3 0 ABC1 family Zeta_toxin PF06414.12 EAQ88975.1 - 0.028 13.7 0.1 7.3 5.8 0.0 2.9 3 0 0 3 3 3 0 Zeta toxin MFS_1 PF07690.16 EAQ88976.1 - 8.5e-33 113.7 26.0 1.3e-32 113.2 26.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily RhoGAP PF00620.27 EAQ88977.1 - 1.8e-37 128.5 0.0 3.5e-37 127.6 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain Esterase PF00756.20 EAQ88978.1 - 2.1e-05 24.3 0.1 8.5e-05 22.3 0.1 1.8 1 1 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 EAQ88978.1 - 3.4e-05 23.4 0.1 5.4e-05 22.8 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 EAQ88978.1 - 6.3e-05 22.9 0.0 9.6e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Esterase_phd PF10503.9 EAQ88978.1 - 0.00017 21.2 0.1 0.00017 21.2 0.1 2.0 2 1 0 2 2 2 1 Esterase PHB depolymerase AXE1 PF05448.12 EAQ88978.1 - 0.17 10.5 0.0 0.26 9.9 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) SH3_3 PF08239.11 EAQ88979.1 - 0.00038 20.7 0.1 0.00094 19.4 0.1 1.7 1 0 0 1 1 1 1 Bacterial SH3 domain DUF1505 PF07403.11 EAQ88979.1 - 0.013 15.7 0.4 0.026 14.7 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1505) DUF3328 PF11807.8 EAQ88980.1 - 5.8e-31 108.0 0.0 7.2e-31 107.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) APH PF01636.23 EAQ88981.1 - 1.2e-16 61.4 0.4 2.6e-16 60.3 0.4 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Sigma70_ner PF04546.13 EAQ88981.1 - 0.018 14.9 4.1 0.018 14.9 4.1 1.7 2 0 0 2 2 2 0 Sigma-70, non-essential region Choline_kinase PF01633.20 EAQ88981.1 - 0.02 14.5 0.0 0.042 13.4 0.0 1.5 1 1 0 1 1 1 0 Choline/ethanolamine kinase RRN3 PF05327.11 EAQ88981.1 - 0.022 13.3 3.9 0.027 13.0 3.9 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 TFB6 PF17110.5 EAQ88981.1 - 0.022 14.5 1.6 0.022 14.5 1.6 1.5 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH AAA_16 PF13191.6 EAQ88981.1 - 0.48 10.8 2.1 0.78 10.1 1.2 1.7 1 1 1 2 2 2 0 AAA ATPase domain PTPRCAP PF15713.5 EAQ88981.1 - 1.3 9.3 16.1 0.8 10.0 13.3 1.8 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated DNA_pol_phi PF04931.13 EAQ88981.1 - 2 6.4 17.1 3 5.8 17.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi ORC_WH_C PF18137.1 EAQ88981.1 - 2.1 8.4 6.1 4.3 7.4 6.1 1.4 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal NOA36 PF06524.12 EAQ88981.1 - 4.4 6.5 12.8 8.9 5.5 12.8 1.4 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.10 EAQ88981.1 - 4.5 7.7 17.8 1 9.8 12.5 2.2 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Nop14 PF04147.12 EAQ88981.1 - 4.7 5.3 12.9 7.3 4.7 12.9 1.2 1 0 0 1 1 1 0 Nop14-like family FAM176 PF14851.6 EAQ88981.1 - 9.4 5.9 8.7 11 5.7 6.5 2.0 2 0 0 2 2 2 0 FAM176 family CDC45 PF02724.14 EAQ88981.1 - 9.6 4.4 12.0 18 3.5 12.0 1.3 1 0 0 1 1 1 0 CDC45-like protein zf-Tim10_DDP PF02953.15 EAQ88982.1 - 5.1e-17 61.3 1.4 6.7e-17 60.9 1.4 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Nup188_C PF18378.1 EAQ88983.1 - 3.7e-120 401.2 0.0 8.1e-120 400.0 0.0 1.5 1 0 0 1 1 1 1 Nuclear pore protein NUP188 C-terminal domain Nup188 PF10487.9 EAQ88983.1 - 3.5e-50 170.9 0.0 2.8e-35 121.5 0.0 2.9 2 2 0 2 2 2 2 Nucleoporin subcomplex protein binding to Pom34 IGPS PF00218.21 EAQ88984.1 - 6.6e-97 323.6 0.0 1.4e-96 322.6 0.0 1.6 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase PRAI PF00697.22 EAQ88984.1 - 1.5e-48 165.2 0.0 3.9e-43 147.5 0.0 2.4 1 1 1 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase GATase PF00117.28 EAQ88984.1 - 1.3e-45 155.5 0.0 2.5e-45 154.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EAQ88984.1 - 0.00019 21.3 0.5 0.0011 18.7 0.5 2.0 1 1 0 1 1 1 1 Peptidase C26 QRPTase_C PF01729.19 EAQ88984.1 - 0.094 12.5 0.1 0.61 9.8 0.0 2.3 3 0 0 3 3 3 0 Quinolinate phosphoribosyl transferase, C-terminal domain Use1 PF09753.9 EAQ88986.1 - 1.6e-07 31.3 7.1 2.8e-07 30.5 5.0 2.0 1 1 0 1 1 1 1 Membrane fusion protein Use1 Tmemb_cc2 PF10267.9 EAQ88986.1 - 0.1 11.7 9.2 0.2 10.8 9.2 1.4 1 1 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Synaptobrevin PF00957.21 EAQ88986.1 - 0.34 10.7 0.1 0.34 10.7 0.1 2.4 3 0 0 3 3 3 0 Synaptobrevin Phage_Gp23 PF10669.9 EAQ88986.1 - 0.9 9.9 6.0 3.1 8.1 2.1 3.0 2 2 1 3 3 3 0 Protein gp23 (Bacteriophage A118) TBCC_N PF16752.5 EAQ88986.1 - 2 8.9 8.8 1.4 9.4 3.9 2.4 2 0 0 2 2 2 0 Tubulin-specific chaperone C N-terminal domain Lin-8 PF03353.15 EAQ88986.1 - 3.4 7.1 8.9 5.5 6.5 8.6 1.6 1 1 0 1 1 1 0 Ras-mediated vulval-induction antagonist Peptidase_S64 PF08192.11 EAQ88986.1 - 6.7 5.1 8.5 11 4.3 8.5 1.3 1 0 0 1 1 1 0 Peptidase family S64 Methyltransf_28 PF02636.17 EAQ88987.1 - 2.3e-40 138.9 0.0 3.3e-40 138.4 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Lung_7-TM_R PF06814.13 EAQ88988.1 - 1.9e-52 178.3 14.0 3.8e-42 144.5 11.2 2.1 1 1 1 2 2 2 2 Lung seven transmembrane receptor AgrB PF04647.15 EAQ88988.1 - 1.1 8.5 7.8 0.14 11.5 2.2 2.1 2 0 0 2 2 2 0 Accessory gene regulator B DUF4271 PF14093.6 EAQ88988.1 - 1.9 8.3 13.4 8.1 6.3 13.3 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4271) Cwf_Cwc_15 PF04889.12 EAQ88988.1 - 2 8.1 8.0 3.3 7.4 8.0 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CCSMST1 PF15013.6 EAQ88988.1 - 3.7 7.8 4.6 22 5.3 0.8 3.2 2 2 1 3 3 3 0 CCSMST1 family Pro_isomerase PF00160.21 EAQ88989.1 - 7.3e-45 153.1 0.0 1.4e-44 152.1 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD U-box PF04564.15 EAQ88989.1 - 5.6e-05 23.2 0.0 0.00032 20.8 0.0 2.2 2 0 0 2 2 2 1 U-box domain zf-NOSIP PF15906.5 EAQ88989.1 - 0.0013 18.8 0.0 0.0031 17.6 0.0 1.6 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein Fungal_trans_2 PF11951.8 EAQ88990.1 - 4.2e-13 48.9 0.7 2.2e-07 30.0 0.1 2.6 2 1 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 EAQ88990.1 - 4.4e-07 29.9 12.5 9.7e-07 28.8 12.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain KTI12 PF08433.10 EAQ88991.1 - 5.1e-35 121.2 0.0 6e-34 117.7 0.0 2.0 2 0 0 2 2 2 1 Chromatin associated protein KTI12 PRCC PF10253.9 EAQ88991.1 - 0.03 15.1 3.6 0.042 14.7 3.6 1.3 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting ORC6 PF05460.13 EAQ88991.1 - 0.54 9.5 4.1 0.64 9.2 4.1 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) DnaJ PF00226.31 EAQ88992.1 - 1.8e-16 60.0 1.5 4.4e-16 58.8 1.5 1.7 1 0 0 1 1 1 1 DnaJ domain MFS_1 PF07690.16 EAQ88992.1 - 0.012 14.5 0.1 0.025 13.5 0.1 1.4 1 0 0 1 1 1 0 Major Facilitator Superfamily DUF4229 PF14012.6 EAQ88992.1 - 0.084 13.0 0.4 0.54 10.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) Phage_XkdX PF09693.10 EAQ88992.1 - 0.12 12.5 0.0 0.52 10.4 0.0 2.1 2 0 0 2 2 2 0 Phage uncharacterised protein (Phage_XkdX) PGA2 PF07543.12 EAQ88992.1 - 0.23 11.4 2.2 0.61 10.1 2.2 1.7 1 0 0 1 1 1 0 Protein trafficking PGA2 TPR_1 PF00515.28 EAQ88993.1 - 3.7e-40 134.1 1.7 1.1e-07 31.3 0.1 8.0 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_2 PF07719.17 EAQ88993.1 - 2.3e-33 111.6 3.4 1.2e-06 28.1 0.0 8.5 8 1 0 8 8 8 6 Tetratricopeptide repeat DnaJ PF00226.31 EAQ88993.1 - 7.3e-27 93.3 5.1 9.1e-27 93.0 2.3 2.5 2 0 0 2 2 2 1 DnaJ domain TPR_19 PF14559.6 EAQ88993.1 - 2.6e-25 88.7 3.0 1.6e-08 34.9 0.0 5.8 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 EAQ88993.1 - 3.5e-24 84.2 1.7 2.7e-05 23.8 0.0 6.7 5 2 2 7 7 7 4 TPR repeat TPR_16 PF13432.6 EAQ88993.1 - 7.9e-21 74.4 0.7 1.5e-05 25.5 0.0 5.2 6 0 0 6 6 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 EAQ88993.1 - 3.2e-19 67.5 0.2 0.00019 21.4 0.1 6.9 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 EAQ88993.1 - 3.3e-17 61.2 0.1 0.067 13.2 0.0 6.7 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_12 PF13424.6 EAQ88993.1 - 5.8e-15 55.3 2.4 0.19 12.1 0.1 6.5 5 1 0 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.6 EAQ88993.1 - 4.3e-14 52.0 14.7 0.00011 22.7 0.1 7.8 7 2 3 10 10 6 3 Tetratricopeptide repeat ANAPC3 PF12895.7 EAQ88993.1 - 1.3e-12 47.8 0.7 0.01 16.0 0.0 4.5 3 1 2 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 EAQ88993.1 - 5.4e-12 45.5 3.5 0.099 13.3 0.0 7.2 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 EAQ88993.1 - 6.9e-11 41.8 9.1 0.0055 17.0 0.0 6.6 7 0 0 7 7 5 3 Tetratricopeptide repeat TPR_9 PF13371.6 EAQ88993.1 - 1.5e-10 41.0 8.6 0.0097 16.0 0.1 4.9 3 2 1 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 EAQ88993.1 - 7.8e-08 32.0 0.6 0.093 12.6 0.0 5.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_15 PF13429.6 EAQ88993.1 - 2.2e-06 27.1 4.0 0.019 14.2 0.1 4.3 2 2 1 3 3 3 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EAQ88993.1 - 8.8e-06 25.7 1.2 5.6 7.1 0.1 4.9 5 0 0 5 5 5 1 Fis1 C-terminal tetratricopeptide repeat BTAD PF03704.17 EAQ88993.1 - 0.00028 21.4 2.3 15 6.0 0.0 4.4 3 1 0 3 3 3 0 Bacterial transcriptional activator domain SHNi-TPR PF10516.9 EAQ88993.1 - 0.00042 19.7 0.4 0.57 9.7 0.0 3.3 3 0 0 3 3 3 1 SHNi-TPR MIT PF04212.18 EAQ88993.1 - 0.0012 18.9 0.1 1.4 9.0 0.0 4.2 4 1 0 4 4 4 1 MIT (microtubule interacting and transport) domain TPR_4 PF07721.14 EAQ88993.1 - 0.0013 19.2 0.8 1.1 10.1 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat NARP1 PF12569.8 EAQ88993.1 - 0.0041 16.1 1.2 0.12 11.3 0.6 2.7 3 0 0 3 3 3 1 NMDA receptor-regulated protein 1 RRM_3 PF08777.11 EAQ88993.1 - 0.052 13.6 0.0 0.16 12.1 0.0 1.8 1 0 0 1 1 1 0 RNA binding motif TPR_20 PF14561.6 EAQ88993.1 - 0.078 13.3 6.5 2.7 8.4 0.1 3.9 2 1 0 3 3 3 0 Tetratricopeptide repeat Coatomer_E PF04733.14 EAQ88993.1 - 0.083 12.3 0.3 5.5 6.3 0.1 2.8 3 1 0 3 3 3 0 Coatomer epsilon subunit Alkyl_sulf_dimr PF14863.6 EAQ88993.1 - 0.089 13.2 0.4 36 4.8 0.5 3.8 3 1 1 4 4 3 0 Alkyl sulfatase dimerisation MAS20 PF02064.15 EAQ88993.1 - 0.091 12.9 0.0 3.3 7.8 0.0 3.3 2 1 1 3 3 3 0 MAS20 protein import receptor EF-hand_6 PF13405.6 EAQ88994.1 - 7.2e-07 28.6 0.0 1.6e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.32 EAQ88994.1 - 5.3e-05 22.5 0.1 9.7e-05 21.7 0.1 1.5 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.6 EAQ88994.1 - 0.0004 19.8 0.4 0.00065 19.1 0.4 1.4 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 EAQ88994.1 - 0.01 16.2 0.1 0.013 15.9 0.1 1.4 1 1 0 1 1 1 0 EF-hand domain pair EF-hand_8 PF13833.6 EAQ88994.1 - 0.037 13.9 0.1 0.064 13.1 0.1 1.4 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_9 PF14658.6 EAQ88994.1 - 0.039 14.3 0.0 0.061 13.7 0.0 1.2 1 0 0 1 1 1 0 EF-hand domain Afi1 PF07792.12 EAQ88995.1 - 4.1e-47 160.0 1.0 7.7e-47 159.1 1.0 1.5 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.10 EAQ88995.1 - 1.2e-37 128.3 0.0 2.3e-37 127.4 0.0 1.5 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.9 EAQ88995.1 - 1.2e-07 30.8 0.0 0.018 13.8 0.0 3.9 3 1 1 4 4 4 2 Transport protein Avl9 DUF2347 PF09804.9 EAQ88995.1 - 0.098 12.2 0.0 0.42 10.2 0.0 2.1 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) TFIIA PF03153.13 EAQ88995.1 - 0.26 11.2 5.4 0.46 10.4 5.4 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CSRNP_N PF16019.5 EAQ88995.1 - 0.3 11.0 1.5 0.61 10.0 1.5 1.4 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus Nop14 PF04147.12 EAQ88995.1 - 1.3 7.2 8.1 2 6.6 8.1 1.2 1 0 0 1 1 1 0 Nop14-like family Esterase PF00756.20 EAQ88996.1 - 1.6e-49 168.9 0.0 1.9e-49 168.6 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Esterase_phd PF10503.9 EAQ88996.1 - 0.00027 20.5 0.3 0.0023 17.5 0.3 2.0 1 1 0 1 1 1 1 Esterase PHB depolymerase Hydrolase_4 PF12146.8 EAQ88996.1 - 0.0092 15.3 0.0 0.016 14.5 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EAQ88996.1 - 0.045 13.2 0.0 0.076 12.5 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family NACHT PF05729.12 EAQ88998.1 - 1.6e-07 31.4 0.1 0.016 15.2 0.0 2.8 2 0 0 2 2 2 2 NACHT domain AAA_16 PF13191.6 EAQ88998.1 - 0.00048 20.6 1.2 0.022 15.1 1.2 2.5 1 1 0 1 1 1 1 AAA ATPase domain Trans_reg_C PF00486.28 EAQ88998.1 - 0.0027 17.7 0.2 2.7 8.1 0.0 2.9 2 0 0 2 2 2 2 Transcriptional regulatory protein, C terminal Spc7 PF08317.11 EAQ88998.1 - 0.0041 16.1 1.1 0.0063 15.4 1.1 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein ABC_tran PF00005.27 EAQ88998.1 - 0.0057 17.2 0.2 0.018 15.6 0.2 1.8 1 1 0 1 1 1 1 ABC transporter AAA_18 PF13238.6 EAQ88998.1 - 0.017 15.6 0.0 0.086 13.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF676 PF05057.14 EAQ88998.1 - 0.034 13.7 0.1 0.07 12.6 0.1 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) RNA_helicase PF00910.22 EAQ88998.1 - 0.058 13.8 0.1 0.13 12.7 0.1 1.6 1 0 0 1 1 1 0 RNA helicase Occludin_ELL PF07303.13 EAQ88998.1 - 0.13 13.0 1.1 0.34 11.6 1.1 1.7 1 0 0 1 1 1 0 Occludin homology domain AAA_30 PF13604.6 EAQ88998.1 - 0.14 11.9 0.0 0.42 10.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain YscO PF07321.12 EAQ88998.1 - 0.14 12.1 4.3 0.29 11.1 4.3 1.5 1 0 0 1 1 1 0 Type III secretion protein YscO NB-ARC PF00931.22 EAQ88998.1 - 0.16 11.1 0.0 0.34 10.1 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Cluap1 PF10234.9 EAQ88998.1 - 0.22 10.9 1.8 0.36 10.2 1.8 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 DUF1640 PF07798.11 EAQ88998.1 - 0.24 11.4 1.3 0.49 10.4 1.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) OmpH PF03938.14 EAQ88998.1 - 0.3 11.4 2.1 0.36 11.2 0.8 1.8 2 0 0 2 2 1 0 Outer membrane protein (OmpH-like) DUF4201 PF13870.6 EAQ88998.1 - 0.42 10.3 2.9 0.83 9.4 2.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) GARS_A PF01071.19 EAQ89001.1 - 1.8e-82 275.8 0.0 2.7e-82 275.2 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain AIRS_C PF02769.22 EAQ89001.1 - 1.4e-34 119.5 0.4 3e-34 118.4 0.4 1.5 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_N PF02844.15 EAQ89001.1 - 3.4e-34 117.5 0.1 1.2e-33 115.7 0.0 2.1 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.16 EAQ89001.1 - 4.6e-28 97.3 0.8 2.3e-27 95.1 0.1 2.6 3 0 0 3 3 3 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.24 EAQ89001.1 - 7.6e-14 52.1 2.5 3.3e-13 50.1 2.5 2.2 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain CPSase_L_D2 PF02786.17 EAQ89001.1 - 0.00013 21.5 0.0 0.00026 20.6 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp PF02222.22 EAQ89001.1 - 0.0019 17.8 0.0 0.0033 17.0 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 EAQ89001.1 - 0.084 12.9 0.0 0.27 11.3 0.0 1.9 1 0 0 1 1 1 0 ATP-grasp domain ATP-grasp_4 PF13535.6 EAQ89001.1 - 0.16 11.5 0.0 0.39 10.3 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain ATP-grasp_2 PF08442.10 EAQ89001.1 - 0.17 11.4 0.0 0.31 10.6 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp domain Acyltransferase PF01553.21 EAQ89002.1 - 7.2e-32 109.8 0.0 1.1e-31 109.2 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase ABC2_membrane_3 PF12698.7 EAQ89002.1 - 5 6.1 10.6 7.1 5.6 10.6 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF4484 PF14831.6 EAQ89003.1 - 1.6e-63 214.6 0.0 1.6e-63 214.6 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4484) DUF2347 PF09804.9 EAQ89003.1 - 9.5e-52 176.3 0.0 1.7e-43 149.3 0.0 2.4 1 1 1 2 2 2 2 Uncharacterized conserved protein (DUF2347) SPA PF08616.10 EAQ89003.1 - 0.19 11.7 0.0 0.39 10.7 0.0 1.4 1 0 0 1 1 1 0 Stabilization of polarity axis WD40 PF00400.32 EAQ89004.1 - 2.7e-56 186.2 14.0 1.6e-08 35.0 0.2 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.10 EAQ89004.1 - 2.3e-17 63.0 9.9 4.1e-17 62.3 9.9 1.4 1 0 0 1 1 1 1 Tup N-terminal ANAPC4_WD40 PF12894.7 EAQ89004.1 - 1.3e-15 57.5 0.1 0.0012 19.1 0.0 5.2 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EAQ89004.1 - 5.2e-07 29.3 0.0 0.15 11.3 0.0 4.8 4 1 1 5 5 5 2 WD40-like domain Ge1_WD40 PF16529.5 EAQ89004.1 - 3.8e-06 26.1 0.3 0.6 9.0 0.0 4.6 2 1 3 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EAQ89004.1 - 9e-05 21.3 0.7 0.96 8.0 0.0 4.1 1 1 3 4 4 4 2 Nucleoporin Nup120/160 Golgin_A5 PF09787.9 EAQ89004.1 - 0.012 15.1 2.8 0.016 14.7 2.8 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 Cytochrom_D1 PF02239.16 EAQ89004.1 - 0.084 11.4 0.1 2.1 6.8 0.1 2.4 1 1 1 2 2 2 0 Cytochrome D1 heme domain Nbas_N PF15492.6 EAQ89004.1 - 0.094 12.0 0.1 15 4.8 0.0 3.2 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal DUF3328 PF11807.8 EAQ89005.1 - 1.4e-39 136.2 0.0 2.2e-39 135.5 0.0 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) DUF2015 PF09435.10 EAQ89006.1 - 1.4e-45 153.7 0.0 1.6e-45 153.5 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) Ribosomal_L28e PF01778.17 EAQ89008.1 - 1.7e-34 119.0 0.8 2.5e-34 118.5 0.8 1.2 1 0 0 1 1 1 1 Ribosomal L28e protein family Ldh_1_C PF02866.18 EAQ89010.1 - 3.1e-48 163.9 0.0 4.5e-48 163.3 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 EAQ89010.1 - 6.9e-43 146.1 0.2 9.9e-43 145.6 0.2 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 EAQ89010.1 - 0.0091 15.0 0.0 0.014 14.4 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_hydro_4 PF02056.16 EAQ89010.1 - 0.14 11.7 0.1 8.2 5.9 0.1 2.3 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase TRAPP PF04051.16 EAQ89011.1 - 4.7e-35 120.4 0.0 2.4e-24 85.7 0.0 2.1 1 1 1 2 2 2 2 Transport protein particle (TRAPP) component PINIT PF14324.6 EAQ89012.1 - 1.1e-43 149.1 0.0 2e-43 148.2 0.0 1.4 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.20 EAQ89012.1 - 7.6e-23 80.0 5.0 1.3e-22 79.3 5.0 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 EAQ89012.1 - 3.1e-05 23.7 0.9 8.3e-05 22.3 0.9 1.8 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit SAP PF02037.27 EAQ89012.1 - 3.9e-05 23.3 0.0 8.4e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 SAP domain zf-Sec23_Sec24 PF04810.15 EAQ89012.1 - 0.025 14.6 1.1 0.054 13.5 0.7 1.8 1 1 0 1 1 1 0 Sec23/Sec24 zinc finger FYVE_2 PF02318.16 EAQ89012.1 - 0.13 12.5 0.2 0.23 11.7 0.2 1.3 1 0 0 1 1 1 0 FYVE-type zinc finger zf-C3HC4_4 PF15227.6 EAQ89012.1 - 0.17 12.1 4.6 0.34 11.1 4.6 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 EAQ89012.1 - 0.76 9.8 3.0 1.4 8.9 3.0 1.5 1 0 0 1 1 1 0 zinc-RING finger domain DUF2423 PF10338.9 EAQ89013.1 - 2.8e-17 62.6 5.8 5.1e-17 61.8 5.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2423) Sulfatase PF00884.23 EAQ89013.1 - 0.013 14.9 0.0 0.41 10.0 0.0 2.2 2 0 0 2 2 2 0 Sulfatase Phosphodiest PF01663.22 EAQ89013.1 - 0.1 12.2 0.1 3.9 7.0 0.0 2.2 2 0 0 2 2 2 0 Type I phosphodiesterase / nucleotide pyrophosphatase Cnd3 PF12719.7 EAQ89014.1 - 1.2e-67 228.2 0.4 7.7e-67 225.5 0.1 2.4 2 1 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 EAQ89014.1 - 2.4e-06 27.9 7.3 0.031 14.7 0.5 4.4 3 1 1 4 4 4 3 HEAT repeats HEAT PF02985.22 EAQ89014.1 - 2.1e-05 24.4 4.0 0.16 12.3 0.0 5.5 6 0 0 6 6 6 1 HEAT repeat Cnd1 PF12717.7 EAQ89014.1 - 0.021 14.9 2.9 2.9 7.9 0.0 4.5 4 1 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 EAQ89014.1 - 0.094 13.3 1.6 10 6.7 0.1 4.3 3 0 0 3 3 3 0 HEAT-like repeat RRM_1 PF00076.22 EAQ89015.1 - 1.5e-60 200.9 0.3 1.2e-18 66.6 0.0 6.1 6 0 0 6 6 6 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 EAQ89015.1 - 2.1e-07 31.3 0.5 5.7 7.1 0.0 6.4 4 3 2 6 6 6 2 Cytosolic domain of 10TM putative phosphate transporter RRM_Rrp7 PF17799.1 EAQ89015.1 - 6.5e-05 22.8 0.4 0.2 11.5 0.1 3.4 2 1 1 3 3 3 2 Rrp7 RRM-like N-terminal domain RRM_7 PF16367.5 EAQ89015.1 - 0.0026 17.8 0.0 23 5.2 0.0 3.8 3 0 0 3 3 3 0 RNA recognition motif BUD22 PF09073.10 EAQ89015.1 - 0.0033 16.8 27.2 0.0033 16.8 27.2 2.9 3 0 0 3 3 3 1 BUD22 RNA_bind PF08675.11 EAQ89015.1 - 0.087 12.9 0.0 0.71 9.9 0.0 2.3 2 0 0 2 2 2 0 RNA binding domain TFIIA PF03153.13 EAQ89015.1 - 0.95 9.4 24.1 0.12 12.3 19.4 1.9 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Nop14 PF04147.12 EAQ89015.1 - 4.4 5.4 36.1 11 4.1 36.1 1.6 1 0 0 1 1 1 0 Nop14-like family Phasin PF05597.11 EAQ89016.1 - 0.039 14.0 3.0 0.054 13.5 0.5 2.1 2 0 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF934 PF06073.12 EAQ89016.1 - 0.076 12.9 0.1 1.3 8.9 0.0 2.4 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF934) Mg_trans_NIPA PF05653.14 EAQ89017.1 - 3.2e-60 203.8 10.6 1.2e-57 195.3 7.5 2.2 2 0 0 2 2 2 2 Magnesium transporter NIPA SLC35F PF06027.12 EAQ89017.1 - 0.0065 16.0 3.5 1.5 8.3 1.1 2.3 2 0 0 2 2 2 2 Solute carrier family 35 F-box_4 PF15966.5 EAQ89017.1 - 0.011 15.6 0.0 0.023 14.6 0.0 1.4 1 0 0 1 1 1 0 F-box F-box PF00646.33 EAQ89017.1 - 0.032 14.1 0.5 0.086 12.7 0.5 1.8 1 0 0 1 1 1 0 F-box domain EamA PF00892.20 EAQ89017.1 - 0.049 13.8 21.1 0.036 14.2 1.3 3.7 3 1 0 3 3 3 0 EamA-like transporter family LysE PF01810.18 EAQ89017.1 - 2.5 7.5 10.1 2.2 7.7 0.2 3.1 2 1 1 3 3 3 0 LysE type translocator DUF373 PF04123.13 EAQ89017.1 - 5.4 6.4 9.9 10 5.5 8.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF373) DUF4203 PF13886.6 EAQ89018.1 - 0.0011 18.6 0.1 0.0017 18.0 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) TMEM208_SND2 PF05620.11 EAQ89019.1 - 2.8 7.7 4.0 3.3 7.5 0.0 2.9 3 1 1 4 4 4 0 SRP-independent targeting protein 2/TMEM208 Erf4 PF10256.9 EAQ89020.1 - 8.9e-39 132.2 0.0 1.2e-38 131.8 0.0 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family AMP-binding PF00501.28 EAQ89021.1 - 4.9e-31 107.8 0.0 8.3e-31 107.0 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EAQ89021.1 - 3.1e-20 72.9 0.3 8.1e-20 71.6 0.3 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain HNH_2 PF13391.6 EAQ89022.1 - 2.1e-05 24.6 0.1 4.4e-05 23.5 0.1 1.6 1 0 0 1 1 1 1 HNH endonuclease Glyco_hydro_1 PF00232.18 EAQ89023.1 - 7.3e-148 492.7 0.1 8.8e-148 492.5 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 AID PF18767.1 EAQ89023.1 - 0.052 13.6 0.0 0.099 12.7 0.0 1.4 1 0 0 1 1 1 0 Activation induced deaminase SSrecog PF03531.14 EAQ89026.1 - 1.2e-29 102.0 0.2 5.9e-29 99.8 0.0 2.3 2 0 0 2 2 2 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.12 EAQ89026.1 - 3.1e-23 82.0 0.0 2.5e-22 79.1 0.0 2.1 2 0 0 2 2 2 1 Histone chaperone Rttp106-like POB3_N PF17292.2 EAQ89026.1 - 1.8e-17 63.5 0.6 2.8e-13 50.1 0.0 3.8 3 1 1 4 4 4 2 POB3-like N-terminal PH domain Cwf_Cwc_15 PF04889.12 EAQ89026.1 - 3 7.5 23.2 5.6 6.6 23.2 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 EAQ89026.1 - 3.6 6.8 21.2 7.3 5.8 21.2 1.5 1 0 0 1 1 1 0 NOA36 protein Xpo1 PF08389.12 EAQ89027.1 - 4e-40 137.3 1.0 6.4e-39 133.4 0.0 3.3 3 1 1 4 4 4 1 Exportin 1-like protein HEAT PF02985.22 EAQ89027.1 - 0.00095 19.2 1.2 3.3 8.2 0.0 5.2 6 0 0 6 6 6 1 HEAT repeat HEAT_EZ PF13513.6 EAQ89027.1 - 0.18 12.3 5.4 59 4.3 0.2 5.6 5 1 1 6 6 6 0 HEAT-like repeat Peptidase_M18 PF02127.15 EAQ89029.1 - 2.8e-176 586.6 0.0 3.2e-176 586.4 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 EAQ89029.1 - 5e-05 22.5 0.0 0.0012 17.9 0.0 2.2 1 1 1 2 2 2 2 M42 glutamyl aminopeptidase KIX_2 PF16987.5 EAQ89031.1 - 7.4e-05 22.7 0.1 7.4e-05 22.7 0.1 3.7 5 0 0 5 5 5 1 KIX domain Whi5 PF08528.11 EAQ89032.1 - 1.2e-10 40.7 0.0 2.7e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 Whi5 like NRDE-2 PF08424.10 EAQ89033.1 - 1.3e-84 284.1 0.0 3.8e-84 282.6 0.0 1.7 3 0 0 3 3 3 1 NRDE-2, necessary for RNA interference Voltage_CLC PF00654.20 EAQ89034.1 - 2.3e-90 303.4 20.0 3e-90 303.0 20.0 1.1 1 0 0 1 1 1 1 Voltage gated chloride channel Cation_efflux PF01545.21 EAQ89035.1 - 9e-50 169.2 3.1 1.1e-49 168.9 3.1 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 EAQ89035.1 - 0.00037 20.6 0.9 0.00063 19.8 0.1 1.8 2 0 0 2 2 2 1 Dimerisation domain of Zinc Transporter Chorion_2 PF03964.15 EAQ89035.1 - 0.031 15.1 1.6 0.031 15.1 1.6 2.4 2 0 0 2 2 2 0 Chorion family 2 SIR2 PF02146.17 EAQ89036.1 - 3.1e-29 102.1 0.0 4.4e-29 101.7 0.0 1.2 1 0 0 1 1 1 1 Sir2 family Peptidase_C50 PF03568.17 EAQ89037.1 - 3.6e-167 556.5 0.0 8.2e-167 555.3 0.0 1.7 1 0 0 1 1 1 1 Peptidase family C50 CHAT PF12770.7 EAQ89037.1 - 0.00028 20.4 7.9 0.00031 20.3 0.0 3.8 3 1 0 3 3 3 1 CHAT domain TPR_12 PF13424.6 EAQ89037.1 - 0.11 12.8 33.0 0.11 12.8 1.7 7.2 6 1 0 7 7 7 0 Tetratricopeptide repeat Glyco_hydro_7 PF00840.20 EAQ89038.1 - 1e-130 436.4 4.6 1.3e-130 436.1 4.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Ank_2 PF12796.7 EAQ89039.1 - 0.072 13.7 0.1 0.3 11.7 0.0 2.1 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAQ89039.1 - 0.16 12.6 0.1 0.83 10.3 0.1 2.2 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Melibiase_2 PF16499.5 EAQ89041.1 - 1.3e-67 227.9 1.2 2e-67 227.3 1.2 1.3 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 EAQ89041.1 - 1.1e-09 38.3 0.4 1.8e-07 31.1 0.0 2.4 2 0 0 2 2 2 2 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 EAQ89041.1 - 2.6e-05 23.3 0.0 0.00011 21.4 0.0 1.8 1 1 1 2 2 2 1 Melibiase Glyco_hyd_65N_2 PF14498.6 EAQ89042.1 - 8.5e-55 186.2 0.2 1.3e-54 185.6 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Zn_clus PF00172.18 EAQ89044.1 - 1e-07 32.0 11.3 1.7e-07 31.2 11.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EAQ89044.1 - 1.5e-06 27.4 0.1 2.7e-06 26.6 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain CCDC92 PF14916.6 EAQ89044.1 - 0.058 13.2 0.7 0.11 12.3 0.1 1.7 2 0 0 2 2 2 0 Coiled-coil domain of unknown function Pox_A_type_inc PF04508.12 EAQ89044.1 - 1.7 8.6 4.0 3.5 7.6 4.0 1.5 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat ADH_N PF08240.12 EAQ89045.1 - 1.1e-22 80.0 1.1 1.9e-22 79.2 1.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EAQ89045.1 - 7.1e-17 61.6 0.0 1.2e-16 60.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 EAQ89045.1 - 0.00026 20.4 0.0 0.0004 19.8 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 EAQ89045.1 - 0.00032 20.1 0.1 0.0005 19.4 0.1 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HscB_4_cys PF18256.1 EAQ89045.1 - 6.3 6.7 6.4 1 9.2 2.2 1.9 2 0 0 2 2 2 0 Co-chaperone HscB tetracysteine metal binding motif Glyco_hydro_35 PF01301.19 EAQ89046.1 - 2.5e-82 277.0 0.0 3e-82 276.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.15 EAQ89046.1 - 4.7e-09 36.1 0.4 2.3e-08 33.8 0.4 1.8 1 1 0 1 1 1 1 Beta-galactosidase BetaGal_dom4_5 PF13364.6 EAQ89046.1 - 0.00043 20.8 0.0 0.00094 19.7 0.0 1.5 1 0 0 1 1 1 1 Beta-galactosidase jelly roll domain Cellulase PF00150.18 EAQ89046.1 - 0.03 13.8 0.0 0.048 13.1 0.0 1.2 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_14 PF01373.17 EAQ89046.1 - 0.057 12.4 0.0 0.099 11.6 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 14 zf-RVT PF13966.6 EAQ89048.1 - 0.093 13.5 0.0 0.25 12.1 0.0 1.6 2 0 0 2 2 2 0 zinc-binding in reverse transcriptase Zn_clus PF00172.18 EAQ89051.1 - 5.9e-10 39.1 10.8 9.7e-10 38.4 10.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Med3 PF11593.8 EAQ89051.1 - 0.1 11.7 0.8 0.13 11.4 0.8 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Fungal_trans PF04082.18 EAQ89052.1 - 9.1e-11 41.3 0.0 2.2e-10 40.0 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Kri1_C PF12936.7 EAQ89053.1 - 1.3e-28 99.0 0.1 1.3e-28 99.0 0.1 4.2 6 0 0 6 6 6 1 KRI1-like family C-terminal Kri1 PF05178.12 EAQ89053.1 - 2.2e-27 95.6 23.3 2.2e-27 95.6 23.3 5.8 5 1 0 6 6 6 1 KRI1-like family Mig-14 PF07395.11 EAQ89053.1 - 1 8.7 8.0 4.5 6.6 0.4 2.3 2 0 0 2 2 2 0 Mig-14 Inhibitor_I71 PF12628.7 EAQ89053.1 - 4.2 7.2 6.8 2.6 7.8 0.1 3.1 3 0 0 3 3 3 0 Falstatin, cysteine peptidase inhibitor Ras PF00071.22 EAQ89054.1 - 5e-58 195.3 0.0 5.7e-58 195.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAQ89054.1 - 2.3e-34 118.2 0.0 3.3e-34 117.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAQ89054.1 - 1.1e-13 51.0 0.0 1.9e-13 50.2 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EAQ89054.1 - 8.8e-06 25.4 0.0 1.3e-05 24.8 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EAQ89054.1 - 5.4e-05 23.3 0.0 9.1e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EAQ89054.1 - 0.00014 21.3 0.0 0.00021 20.8 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 EAQ89054.1 - 0.00074 19.9 0.0 0.00082 19.8 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 EAQ89054.1 - 0.071 13.0 0.0 1.5 8.7 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_22 PF13401.6 EAQ89054.1 - 0.19 12.0 0.0 0.98 9.7 0.0 2.0 2 1 0 2 2 2 0 AAA domain BUD22 PF09073.10 EAQ89056.1 - 0.45 9.8 11.4 0.55 9.5 11.4 1.2 1 0 0 1 1 1 0 BUD22 GCV_T PF01571.21 EAQ89057.1 - 5.6e-07 29.2 0.0 9.8e-07 28.4 0.0 1.3 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain DnaJ PF00226.31 EAQ89058.1 - 4.4e-11 42.7 0.1 1.6e-10 41.0 0.1 2.0 1 0 0 1 1 1 1 DnaJ domain SAPS PF04499.15 EAQ89058.1 - 3.9 6.2 7.0 4.6 5.9 7.0 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CorA PF01544.18 EAQ89059.1 - 1.1e-14 54.4 0.0 2.7e-14 53.2 0.0 1.6 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Spem1 PF15670.5 EAQ89059.1 - 0.56 9.7 0.0 0.56 9.7 0.0 3.0 4 0 0 4 4 4 0 Spermatid maturation protein 1 DUF959 PF06121.14 EAQ89059.1 - 0.84 9.9 6.6 3.8 7.7 2.1 2.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF959) DIOX_N PF14226.6 EAQ89060.1 - 1.6e-23 83.7 0.0 2.7e-23 82.9 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EAQ89060.1 - 5.8e-18 65.2 0.0 1.1e-17 64.4 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily HNOB PF07700.15 EAQ89060.1 - 0.17 11.9 0.0 0.33 10.9 0.0 1.4 1 0 0 1 1 1 0 Haem-NO-binding Helicase_C PF00271.31 EAQ89062.1 - 6e-30 103.8 0.0 1.1e-29 102.9 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EAQ89062.1 - 3e-08 33.6 0.0 5.8e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase CDC45 PF02724.14 EAQ89062.1 - 0.019 13.3 5.6 0.024 12.9 5.6 1.1 1 0 0 1 1 1 0 CDC45-like protein LSDAT_prok PF18171.1 EAQ89062.1 - 0.1 11.8 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 SLOG in TRPM, prokaryote Pex14_N PF04695.13 EAQ89062.1 - 0.65 10.6 9.9 0.79 10.4 2.8 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region XRCC4 PF06632.12 EAQ89062.1 - 6.8 5.4 8.2 11 4.8 8.2 1.2 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Nop14 PF04147.12 EAQ89062.1 - 9.5 4.3 10.9 14 3.8 10.9 1.1 1 0 0 1 1 1 0 Nop14-like family Pkinase PF00069.25 EAQ89063.1 - 2.3e-62 210.7 0.0 2.8e-62 210.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ89063.1 - 2.8e-34 118.6 0.0 3.6e-34 118.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAQ89063.1 - 1.3e-06 27.9 0.0 2.1e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EAQ89063.1 - 9.2e-05 21.4 0.0 0.00013 20.9 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 EAQ89063.1 - 0.0087 15.7 0.0 0.89 9.1 0.0 2.2 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 TruD PF01142.18 EAQ89064.1 - 4.5e-64 216.8 0.0 2.2e-57 194.7 0.0 4.0 3 1 0 3 3 3 3 tRNA pseudouridine synthase D (TruD) DUF1804 PF08822.11 EAQ89064.1 - 0.12 12.3 0.6 0.33 10.9 0.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1804) CH PF00307.31 EAQ89065.1 - 2.8e-47 159.4 0.1 6.9e-23 80.9 0.0 3.0 3 0 0 3 3 3 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.10 EAQ89065.1 - 6.4e-24 83.8 0.1 4.3e-23 81.2 0.0 2.5 2 0 0 2 2 2 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.8 EAQ89065.1 - 4.9e-12 45.5 0.1 3.3e-06 26.9 0.1 2.7 2 0 0 2 2 2 2 CAMSAP CH domain Spectrin PF00435.21 EAQ89065.1 - 9.9e-06 26.0 3.1 0.0023 18.4 1.2 2.6 2 0 0 2 2 2 2 Spectrin repeat EF-hand_6 PF13405.6 EAQ89065.1 - 9.3e-05 22.1 0.8 0.00066 19.4 0.1 2.9 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.32 EAQ89065.1 - 0.0043 16.5 0.4 0.047 13.2 0.0 2.6 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 EAQ89065.1 - 0.016 15.0 1.3 0.14 12.0 0.2 2.8 2 1 1 3 3 3 0 EF-hand domain pair EF-hand_7 PF13499.6 EAQ89065.1 - 0.045 14.2 4.2 0.08 13.4 2.1 2.6 2 0 0 2 2 2 0 EF-hand domain pair zf-RRPl_C4 PF17026.5 EAQ89065.1 - 0.17 12.0 0.3 0.45 10.6 0.1 1.8 2 0 0 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type Sipho_Gp157 PF05565.11 EAQ89065.1 - 0.46 10.5 2.3 21 5.1 0.1 2.4 2 0 0 2 2 2 0 Siphovirus Gp157 VPS9 PF02204.18 EAQ89066.1 - 1.1e-27 96.3 0.1 2.1e-27 95.3 0.1 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain K_oxygenase PF13434.6 EAQ89066.1 - 0.053 12.6 0.1 0.091 11.9 0.1 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) MRFAP1 PF15155.6 EAQ89067.1 - 0.0067 16.9 9.9 0.01 16.3 9.9 1.2 1 0 0 1 1 1 1 MORF4 family-associated protein1 HEPN_AbiU2 PF18734.1 EAQ89067.1 - 0.051 13.1 1.3 0.57 9.7 1.3 2.2 1 1 0 1 1 1 0 AbiU2 KxDL PF10241.9 EAQ89067.1 - 0.2 12.0 0.6 0.42 10.9 0.3 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein V-ATPase_G PF03179.15 EAQ89067.1 - 5.1 7.7 13.7 6.7 7.3 12.8 1.6 2 0 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit Lipase_3 PF01764.25 EAQ89068.1 - 3.9e-06 26.8 0.0 7.6e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) UPF0227 PF05728.12 EAQ89068.1 - 0.023 14.6 0.0 0.041 13.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Hydrolase_4 PF12146.8 EAQ89068.1 - 0.044 13.0 0.0 0.073 12.3 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 EAQ89068.1 - 0.14 11.9 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family zf-C3HC4 PF00097.25 EAQ89069.1 - 3.1e-07 30.2 4.1 3.1e-07 30.2 4.1 5.2 6 2 0 6 6 6 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EAQ89069.1 - 1.2e-06 28.5 4.2 1.2e-06 28.5 4.2 3.6 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EAQ89069.1 - 4e-06 26.6 5.5 4e-06 26.6 5.5 4.2 3 2 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 EAQ89069.1 - 4.8e-06 26.4 0.5 4.8e-06 26.4 0.5 2.9 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-RING_2 PF13639.6 EAQ89069.1 - 4.9e-05 23.6 7.2 4.9e-05 23.6 7.2 4.3 4 0 0 4 4 4 1 Ring finger domain zf-C3HC4_4 PF15227.6 EAQ89069.1 - 9.8e-05 22.4 4.5 9.8e-05 22.4 4.5 4.2 4 3 0 4 4 4 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 EAQ89069.1 - 0.00012 21.9 4.0 0.00012 21.9 4.0 4.8 5 1 0 5 5 5 1 zinc-RING finger domain SH3_1 PF00018.28 EAQ89069.1 - 0.0029 17.2 0.4 0.018 14.6 0.0 2.3 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 EAQ89069.1 - 0.0099 15.7 2.0 0.016 15.1 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain ECH_1 PF00378.20 EAQ89070.1 - 5.6e-70 235.5 0.1 6.9e-70 235.2 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EAQ89070.1 - 3.6e-30 105.6 0.4 1.1e-28 100.7 0.4 2.0 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Rer1 PF03248.13 EAQ89071.1 - 3.9e-78 261.1 7.5 4.5e-78 260.9 7.5 1.0 1 0 0 1 1 1 1 Rer1 family Paf1 PF03985.13 EAQ89072.1 - 1.1e-35 123.5 22.1 3.8e-22 78.9 0.1 3.7 2 1 0 2 2 2 2 Paf1 Glyco_transf_90 PF05686.12 EAQ89073.1 - 0.15 10.9 9.3 0.79 8.6 0.1 3.5 3 1 0 3 3 3 0 Glycosyl transferase family 90 CCDC53 PF10152.9 EAQ89073.1 - 0.74 10.2 7.2 1.4 9.3 7.2 1.4 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Ribosomal_S8 PF00410.19 EAQ89074.1 - 4.2e-21 75.2 0.0 5.5e-21 74.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 Ribosomal_L7Ae PF01248.26 EAQ89075.1 - 2.8e-28 97.5 0.7 3.4e-28 97.2 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 EAQ89075.1 - 0.065 13.1 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 PELOTA RNA binding domain DUF1846 PF08903.11 EAQ89075.1 - 0.16 10.5 0.0 0.2 10.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1846) Cytomega_UL84 PF06284.11 EAQ89076.1 - 0.0013 17.3 0.0 0.0015 17.1 0.0 1.1 1 0 0 1 1 1 1 Cytomegalovirus UL84 protein Rotamase_3 PF13616.6 EAQ89076.1 - 0.002 18.7 1.2 0.0039 17.7 0.2 1.9 1 1 0 1 1 1 1 PPIC-type PPIASE domain Mtf2_C PF14061.6 EAQ89076.1 - 0.08 13.1 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 Neurochondrin PF05536.11 EAQ89078.1 - 1.2e-64 218.7 0.0 2.4e-64 217.8 0.0 1.4 1 1 0 1 1 1 1 Neurochondrin SSP160 PF06933.11 EAQ89078.1 - 3.1e-05 22.4 10.0 3.4e-05 22.3 4.3 2.2 2 0 0 2 2 2 2 Special lobe-specific silk protein SSP160 DUF3439 PF11921.8 EAQ89078.1 - 1.8 8.5 19.3 0.38 10.7 14.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Voltage_CLC PF00654.20 EAQ89079.1 - 9.5e-53 179.7 19.1 5.6e-52 177.1 20.4 1.6 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 EAQ89079.1 - 0.0015 19.0 0.0 0.029 14.8 0.0 2.4 2 0 0 2 2 2 1 CBS domain AIM3 PF17096.5 EAQ89079.1 - 0.094 13.7 0.2 0.094 13.7 0.2 3.4 4 0 0 4 4 4 0 Altered inheritance of mitochondria protein 3 TCTP PF00838.17 EAQ89080.1 - 1.3e-70 237.1 4.4 1.4e-70 236.9 4.4 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein FA_hydroxylase PF04116.13 EAQ89081.1 - 0.0062 16.9 3.8 0.01 16.1 1.1 2.3 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF2530 PF10745.9 EAQ89081.1 - 8 6.8 8.0 2.1 8.7 0.7 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF2530) Spt5_N PF11942.8 EAQ89082.1 - 3.5 8.7 8.1 0.37 11.8 0.5 2.4 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal PPR_2 PF13041.6 EAQ89083.1 - 1.4e-20 73.2 0.0 2.1e-07 31.0 0.0 5.7 4 1 1 5 5 5 3 PPR repeat family PPR_3 PF13812.6 EAQ89083.1 - 7.6e-20 70.8 0.0 3.5e-07 30.2 0.0 6.5 6 1 2 8 8 8 4 Pentatricopeptide repeat domain PPR PF01535.20 EAQ89083.1 - 5.4e-11 42.0 0.0 0.015 15.5 0.0 6.4 6 0 0 6 6 6 4 PPR repeat PPR_1 PF12854.7 EAQ89083.1 - 2.3e-05 24.0 0.4 0.13 12.0 0.0 4.8 5 0 0 5 5 5 1 PPR repeat PPR_long PF17177.4 EAQ89083.1 - 5.6e-05 22.6 0.0 0.03 13.7 0.0 3.4 2 1 1 4 4 4 2 Pentacotripeptide-repeat region of PRORP His_Phos_2 PF00328.22 EAQ89084.1 - 4.9e-14 52.5 0.0 3.6e-13 49.6 0.0 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) SOG2 PF10428.9 EAQ89085.1 - 0.31 10.2 2.5 0.42 9.8 2.5 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Ras PF00071.22 EAQ89087.1 - 1.5e-51 174.2 0.0 2e-51 173.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAQ89087.1 - 1.6e-18 67.1 0.0 2.3e-18 66.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAQ89087.1 - 1.2e-05 24.8 0.0 1.5e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EAQ89087.1 - 0.013 15.1 0.1 0.17 11.4 0.0 2.4 1 1 0 2 2 2 0 Elongation factor Tu GTP binding domain tRNA-synt_2 PF00152.20 EAQ89088.1 - 3.2e-56 190.7 0.6 7e-48 163.3 0.7 2.0 2 0 0 2 2 2 2 tRNA synthetases class II (D, K and N) RRM_1 PF00076.22 EAQ89090.1 - 7.5e-38 128.2 0.1 9.8e-12 44.5 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EAQ89090.1 - 1.8e-15 56.5 0.0 0.031 14.1 0.0 4.3 4 0 0 4 4 4 4 Occluded RNA-recognition motif RRM PF10378.9 EAQ89090.1 - 2.5e-06 27.1 13.0 2.5e-06 27.1 13.0 3.7 3 1 0 3 3 3 1 Putative RRM domain RRM_7 PF16367.5 EAQ89090.1 - 4.1e-06 26.8 0.0 0.018 15.1 0.0 3.7 3 0 0 3 3 3 2 RNA recognition motif DUF4523 PF15023.6 EAQ89090.1 - 6.2e-05 22.9 0.0 0.19 11.6 0.0 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF4523) RRM_3 PF08777.11 EAQ89090.1 - 0.01 15.8 0.1 0.33 11.0 0.1 2.9 3 0 0 3 3 3 0 RNA binding motif RRM_Rrp7 PF17799.1 EAQ89090.1 - 0.045 13.6 0.0 1.1 9.1 0.0 3.1 2 1 2 4 4 4 0 Rrp7 RRM-like N-terminal domain Nup35_RRM_2 PF14605.6 EAQ89090.1 - 0.11 12.5 0.0 33 4.6 0.0 3.3 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif RNA_bind PF08675.11 EAQ89090.1 - 0.21 11.6 0.3 1.2 9.2 0.0 2.4 3 0 0 3 3 3 0 RNA binding domain Mis12 PF05859.12 EAQ89091.1 - 1.9e-44 151.0 0.0 2.9e-44 150.4 0.0 1.3 1 0 0 1 1 1 1 Mis12 protein YL1 PF05764.13 EAQ89092.1 - 2.2e-48 165.5 46.3 4.9e-27 95.6 15.6 3.7 3 1 1 4 4 4 2 YL1 nuclear protein YL1_C PF08265.11 EAQ89092.1 - 1.1e-13 50.6 1.8 2e-13 49.9 1.8 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain zf-HIT PF04438.16 EAQ89092.1 - 0.055 13.4 0.0 0.087 12.7 0.0 1.3 1 0 0 1 1 1 0 HIT zinc finger PALP PF00291.25 EAQ89093.1 - 1.7e-66 224.6 0.7 2.1e-66 224.3 0.7 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Methyltransf_33 PF10017.9 EAQ89094.1 - 0.02 14.1 0.0 0.024 13.8 0.0 1.1 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent Ribosomal_L19 PF01245.20 EAQ89095.1 - 3.1e-13 49.6 0.4 5.8e-13 48.7 0.4 1.4 1 0 0 1 1 1 1 Ribosomal protein L19 TrkH PF02386.16 EAQ89096.1 - 5.4e-116 388.0 7.3 5.5e-104 348.4 0.8 3.1 2 1 1 3 3 3 3 Cation transport protein ERCC3_RAD25_C PF16203.5 EAQ89097.1 - 1.2e-119 398.0 0.1 2.1e-119 397.2 0.1 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 EAQ89097.1 - 4.2e-32 111.0 0.0 1.1e-31 109.6 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Helicase_C PF00271.31 EAQ89097.1 - 5.5e-13 49.2 0.1 1.8e-12 47.6 0.1 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EAQ89097.1 - 7.6e-12 45.6 0.0 1.6e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 EAQ89097.1 - 3e-06 26.2 0.0 3.9e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-CHY PF05495.12 EAQ89098.1 - 9e-06 26.1 10.7 1.8e-05 25.1 10.7 1.5 1 1 0 1 1 1 1 CHY zinc finger Zn_Tnp_IS1595 PF12760.7 EAQ89098.1 - 0.016 15.2 9.0 0.34 10.9 5.5 2.3 2 0 0 2 2 2 0 Transposase zinc-ribbon domain DUF3797 PF12677.7 EAQ89098.1 - 0.027 14.3 0.9 2.4 8.1 0.1 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF3797) Zn-ribbon_8 PF09723.10 EAQ89098.1 - 0.059 13.5 10.8 0.63 10.2 6.6 2.4 2 0 0 2 2 2 0 Zinc ribbon domain Zn_ribbon_SprT PF17283.2 EAQ89098.1 - 0.13 12.1 5.4 0.74 9.8 1.2 2.3 2 0 0 2 2 2 0 SprT-like zinc ribbon domain zinc_ribbon_4 PF13717.6 EAQ89098.1 - 0.18 11.8 12.3 7.1 6.6 0.0 3.8 4 0 0 4 4 4 0 zinc-ribbon domain RNA_POL_M_15KD PF02150.16 EAQ89098.1 - 0.31 11.0 8.6 5.6 6.9 0.2 3.3 3 0 0 3 3 3 0 RNA polymerases M/15 Kd subunit zinc_ribbon_9 PF14369.6 EAQ89098.1 - 0.82 10.0 11.5 0.81 10.0 5.8 2.7 2 1 1 3 3 3 0 zinc-ribbon HypA PF01155.19 EAQ89098.1 - 1.2 9.2 9.7 0.42 10.7 4.6 2.1 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-TFIIB PF13453.6 EAQ89098.1 - 1.3 8.4 6.4 17 4.8 3.8 2.5 2 1 0 2 2 2 0 Transcription factor zinc-finger zf-H2C2_2 PF13465.6 EAQ89098.1 - 5.3 7.6 17.7 3.3 8.3 1.3 3.2 3 0 0 3 3 3 0 Zinc-finger double domain zf-LITAF-like PF10601.9 EAQ89098.1 - 5.5 7.3 10.0 3.1e+02 1.7 10.0 2.6 1 1 0 1 1 1 0 LITAF-like zinc ribbon domain C1_4 PF07975.12 EAQ89098.1 - 6.9 7.0 12.0 9 6.6 0.3 3.0 1 1 2 3 3 3 0 TFIIH C1-like domain Evr1_Alr PF04777.13 EAQ89098.1 - 7.6 7.1 8.6 87 3.7 8.5 2.4 1 1 1 2 2 2 0 Erv1 / Alr family zf-C2H2_4 PF13894.6 EAQ89098.1 - 8.1 7.6 10.2 44 5.3 0.1 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger OrfB_Zn_ribbon PF07282.11 EAQ89098.1 - 8.9 6.3 9.0 17 5.5 3.8 2.2 1 1 0 2 2 2 0 Putative transposase DNA-binding domain Proteasome PF00227.26 EAQ89099.1 - 3.3e-54 183.3 0.1 4e-54 183.0 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit MAT1-1-2 PF17043.5 EAQ89099.1 - 0.044 13.7 0.0 0.071 13.0 0.0 1.2 1 0 0 1 1 1 0 Mating type protein 1-1-2 of unknown function FAD-oxidase_C PF02913.19 EAQ89100.1 - 5.7e-64 216.2 0.0 8e-64 215.7 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 EAQ89100.1 - 3.4e-37 127.3 0.2 6.2e-37 126.4 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain Keratin_2_head PF16208.5 EAQ89102.1 - 0.095 12.8 15.2 0.15 12.2 15.2 1.2 1 0 0 1 1 1 0 Keratin type II head SelP_N PF04592.14 EAQ89102.1 - 1.6 8.0 6.6 2.4 7.5 6.6 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DNA_ligase_A_M PF01068.21 EAQ89104.1 - 4.6e-54 183.2 1.7 1e-51 175.5 1.7 2.5 1 1 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 EAQ89104.1 - 5e-43 147.4 0.0 1.5e-42 145.9 0.0 1.9 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 EAQ89104.1 - 1.1e-28 99.7 0.0 6.3e-28 97.3 0.0 2.4 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 EAQ89104.1 - 0.00026 21.3 0.4 0.00053 20.3 0.4 1.5 1 0 0 1 1 1 1 RNA ligase DUF725 PF05267.12 EAQ89104.1 - 1.6 8.7 6.4 0.87 9.6 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF725) XRCC4 PF06632.12 EAQ89104.1 - 5.2 5.8 26.3 9.8 4.9 26.3 1.4 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 E1_dh PF00676.20 EAQ89105.1 - 3.1e-114 381.0 0.2 3.8e-114 380.7 0.2 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 EAQ89105.1 - 0.0011 18.2 0.1 0.0022 17.2 0.1 1.5 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase WD40 PF00400.32 EAQ89106.1 - 6.1e-37 125.0 28.0 1.7e-07 31.8 0.2 7.2 7 1 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.7 EAQ89106.1 - 2e-12 46.8 0.8 4e-12 45.8 0.8 1.5 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 EAQ89106.1 - 3.4e-09 36.9 3.5 0.21 11.9 0.0 6.0 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EAQ89106.1 - 2e-06 26.8 9.0 0.13 10.9 0.2 5.4 3 1 3 6 6 6 4 Nucleoporin Nup120/160 F-box PF00646.33 EAQ89106.1 - 2e-05 24.3 1.7 3.7e-05 23.5 1.7 1.5 1 0 0 1 1 1 1 F-box domain PQQ_2 PF13360.6 EAQ89106.1 - 0.0017 18.0 7.0 0.46 10.0 0.1 3.9 2 1 2 4 4 4 2 PQQ-like domain WD40_like PF17005.5 EAQ89106.1 - 0.0031 16.9 0.1 0.34 10.2 0.0 2.5 2 1 1 3 3 3 2 WD40-like domain DUF2242 PF10001.9 EAQ89106.1 - 0.067 13.4 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2242) PQQ_3 PF13570.6 EAQ89106.1 - 4.7 7.8 9.1 9.9 6.8 0.1 4.8 5 1 1 6 6 6 0 PQQ-like domain Zip PF02535.22 EAQ89107.1 - 1.6e-34 119.7 12.9 1.5e-22 80.3 12.2 2.0 1 1 1 2 2 2 2 ZIP Zinc transporter Hat1_N PF10394.9 EAQ89108.1 - 2.9e-50 170.6 0.0 5.2e-50 169.8 0.0 1.4 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_10 PF13673.7 EAQ89108.1 - 0.0021 18.0 0.0 0.004 17.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EAQ89108.1 - 0.052 13.8 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family CLZ PF16526.5 EAQ89108.1 - 0.13 12.6 0.6 0.3 11.5 0.3 1.8 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels UBA2_C PF16195.5 EAQ89108.1 - 0.14 12.8 3.8 0.34 11.6 3.8 1.6 1 0 0 1 1 1 0 SUMO-activating enzyme subunit 2 C-terminus Acetyltransf_7 PF13508.7 EAQ89108.1 - 0.15 12.5 0.0 0.33 11.4 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DASH_Spc19 PF08287.11 EAQ89108.1 - 0.22 11.4 1.3 0.4 10.6 1.3 1.4 1 0 0 1 1 1 0 Spc19 P5CR_dimer PF14748.6 EAQ89109.1 - 7.8e-36 122.5 1.2 7.8e-36 122.5 1.2 1.7 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 EAQ89109.1 - 1.1e-15 57.9 1.6 1.2e-12 48.2 0.1 2.6 2 0 0 2 2 2 2 NADP oxidoreductase coenzyme F420-dependent PDH PF02153.17 EAQ89109.1 - 0.0081 15.2 0.1 0.05 12.6 0.1 2.0 1 1 0 1 1 1 1 Prephenate dehydrogenase ApbA PF02558.16 EAQ89109.1 - 0.055 13.1 0.1 0.055 13.1 0.1 1.9 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA CTK3 PF12243.8 EAQ89110.1 - 1.9e-22 79.5 0.4 2.9e-22 79.0 0.4 1.3 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.8 EAQ89110.1 - 2.2e-19 69.4 17.2 2.9e-19 69.0 16.1 1.7 2 0 0 2 2 2 1 CTD kinase subunit gamma CTK3 C-terminus ParD PF09386.10 EAQ89110.1 - 0.058 13.8 0.3 0.16 12.4 0.3 1.7 1 0 0 1 1 1 0 Antitoxin ParD Ribosomal_L12 PF00542.19 EAQ89111.1 - 4.8e-21 74.9 5.3 6.7e-20 71.2 4.1 2.2 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 EAQ89111.1 - 1.6e-13 50.2 9.6 2e-13 49.8 5.3 3.2 3 1 0 3 3 3 1 Ribosomal protein L7/L12 dimerisation domain AAA_5 PF07728.14 EAQ89112.1 - 9.4e-125 411.1 0.0 2.2e-21 76.3 0.0 9.6 8 1 1 9 9 9 9 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 EAQ89112.1 - 1e-58 196.0 8.7 1.7e-24 86.0 0.0 5.7 5 0 0 5 5 5 3 Midasin AAA lid domain AAA_16 PF13191.6 EAQ89112.1 - 5.5e-33 114.7 23.3 1.6e-05 25.3 0.1 9.5 7 2 1 8 8 8 6 AAA ATPase domain AAA_lid_5 PF17865.1 EAQ89112.1 - 7.8e-31 106.3 1.0 5.7e-30 103.5 0.1 2.8 2 0 0 2 2 2 1 Midasin AAA lid domain AAA_7 PF12775.7 EAQ89112.1 - 4.8e-30 104.4 3.1 2e-05 24.2 0.0 7.2 6 1 0 6 6 6 6 P-loop containing dynein motor region AAA_3 PF07726.11 EAQ89112.1 - 1.1e-28 99.7 0.0 7.2e-10 38.8 0.0 7.2 7 0 0 7 7 6 3 ATPase family associated with various cellular activities (AAA) AAA PF00004.29 EAQ89112.1 - 1.9e-28 99.5 0.2 5e-05 23.7 0.0 7.4 7 0 0 7 7 6 5 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EAQ89112.1 - 1e-24 87.3 1.8 0.00071 19.9 0.0 8.0 7 1 0 7 7 6 6 AAA domain Dynein_heavy PF03028.15 EAQ89112.1 - 1.4e-23 83.3 0.0 0.001 19.1 0.0 8.0 7 0 0 7 7 7 4 Dynein heavy chain region D6 P-loop domain Sigma54_activat PF00158.26 EAQ89112.1 - 1.4e-20 73.7 0.0 0.011 15.5 0.0 6.6 6 0 0 6 6 6 4 Sigma-54 interaction domain AAA_18 PF13238.6 EAQ89112.1 - 1.5e-19 70.9 0.1 0.0091 16.5 0.0 7.0 6 0 0 6 6 6 4 AAA domain ABC_tran PF00005.27 EAQ89112.1 - 3.9e-19 69.5 10.4 0.0065 17.0 0.0 8.2 8 0 0 8 8 7 4 ABC transporter AAA_6 PF12774.7 EAQ89112.1 - 3.9e-19 68.8 0.0 0.002 17.1 0.0 8.5 9 0 0 9 9 8 3 Hydrolytic ATP binding site of dynein motor region AAA_33 PF13671.6 EAQ89112.1 - 7.2e-19 68.4 0.9 0.046 13.9 0.0 7.6 7 1 0 7 7 7 4 AAA domain AAA_14 PF13173.6 EAQ89112.1 - 8.2e-19 67.9 0.0 0.0022 18.0 0.0 7.8 7 0 0 7 7 7 3 AAA domain AAA_30 PF13604.6 EAQ89112.1 - 4.8e-17 62.3 0.0 0.01 15.6 0.0 7.5 6 1 0 6 6 6 3 AAA domain RsgA_GTPase PF03193.16 EAQ89112.1 - 1.8e-16 60.5 2.9 0.04 13.8 0.2 6.8 6 0 0 6 6 6 4 RsgA GTPase TsaE PF02367.17 EAQ89112.1 - 3.8e-16 59.2 2.5 0.033 14.2 0.1 6.5 6 0 0 6 6 6 3 Threonylcarbamoyl adenosine biosynthesis protein TsaE T2SSE PF00437.20 EAQ89112.1 - 4.6e-15 55.4 3.3 0.0063 15.6 0.0 6.3 6 0 0 6 6 6 4 Type II/IV secretion system protein NACHT PF05729.12 EAQ89112.1 - 1e-14 54.8 4.1 0.17 11.8 0.0 7.0 6 0 0 6 6 6 4 NACHT domain Sigma54_activ_2 PF14532.6 EAQ89112.1 - 1.4e-13 51.2 0.4 0.00012 22.2 0.0 6.2 6 0 0 6 6 6 2 Sigma-54 interaction domain RNA_helicase PF00910.22 EAQ89112.1 - 1.7e-13 50.9 0.4 1.4 9.3 0.0 6.9 6 0 0 6 6 6 1 RNA helicase AAA_29 PF13555.6 EAQ89112.1 - 3.2e-13 49.2 0.7 0.0016 18.2 0.0 6.5 6 0 0 6 6 6 1 P-loop containing region of AAA domain Zeta_toxin PF06414.12 EAQ89112.1 - 2e-12 46.8 0.8 0.11 11.8 0.0 7.0 6 0 0 6 6 6 2 Zeta toxin IstB_IS21 PF01695.17 EAQ89112.1 - 1.2e-11 44.6 0.2 0.42 10.3 0.0 7.3 7 0 0 7 7 7 1 IstB-like ATP binding protein RuvB_N PF05496.12 EAQ89112.1 - 4.4e-11 42.8 3.3 0.36 10.6 0.0 6.6 7 0 0 7 7 6 2 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 EAQ89112.1 - 8.7e-11 42.1 4.6 0.11 12.4 0.0 7.1 7 0 0 7 7 7 2 Rad17 P-loop domain AAA_28 PF13521.6 EAQ89112.1 - 1.1e-10 42.0 3.6 1.4 9.1 0.0 7.3 7 0 0 7 7 6 2 AAA domain AAA_25 PF13481.6 EAQ89112.1 - 1.2e-10 41.3 0.3 1 8.9 0.0 5.8 5 0 0 5 5 5 3 AAA domain Mg_chelatase PF01078.21 EAQ89112.1 - 3.5e-10 39.6 2.0 2.5 7.4 0.0 7.8 8 0 0 8 8 8 2 Magnesium chelatase, subunit ChlI ATPase_2 PF01637.18 EAQ89112.1 - 4.7e-10 39.8 0.0 0.077 12.9 0.0 6.2 6 0 0 6 6 5 1 ATPase domain predominantly from Archaea SRP54 PF00448.22 EAQ89112.1 - 5e-10 39.3 1.6 0.48 10.0 0.0 6.7 7 0 0 7 7 6 2 SRP54-type protein, GTPase domain TniB PF05621.11 EAQ89112.1 - 1.5e-08 34.3 0.4 0.83 9.0 0.0 6.1 6 0 0 6 6 6 2 Bacterial TniB protein AAA_24 PF13479.6 EAQ89112.1 - 2.9e-08 33.7 0.1 1.8 8.2 0.0 6.8 7 0 0 7 7 7 1 AAA domain CbiA PF01656.23 EAQ89112.1 - 2.9e-08 33.8 0.0 0.02 15.0 0.0 5.3 5 0 0 5 5 5 2 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_19 PF13245.6 EAQ89112.1 - 7.8e-08 32.8 5.1 3.1 8.1 0.0 6.5 6 0 0 6 6 5 0 AAA domain DUF815 PF05673.13 EAQ89112.1 - 1.2e-07 31.2 1.6 1.7 7.7 0.0 5.7 6 0 0 6 6 6 2 Protein of unknown function (DUF815) Roc PF08477.13 EAQ89112.1 - 1.6e-07 31.6 2.6 11 6.2 0.0 6.4 6 0 0 6 6 6 0 Ras of Complex, Roc, domain of DAPkinase NTPase_1 PF03266.15 EAQ89112.1 - 2.4e-07 30.8 4.7 1.8 8.5 0.0 5.9 5 0 0 5 5 5 2 NTPase MMR_HSR1 PF01926.23 EAQ89112.1 - 7e-07 29.3 2.5 17 5.5 0.0 6.9 6 0 0 6 6 6 0 50S ribosome-binding GTPase ResIII PF04851.15 EAQ89112.1 - 1.4e-06 28.4 0.1 2.8 7.9 0.0 6.1 6 0 0 6 6 6 0 Type III restriction enzyme, res subunit PduV-EutP PF10662.9 EAQ89112.1 - 2.1e-06 27.5 5.2 0.12 12.2 0.0 5.8 6 0 0 6 6 6 1 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 EAQ89112.1 - 3.6e-06 26.9 2.9 2.5 7.8 0.0 6.0 6 0 0 6 6 6 1 Conserved hypothetical ATP binding protein dNK PF01712.19 EAQ89112.1 - 4.6e-06 26.6 3.5 1.7 8.5 0.0 5.8 6 0 0 6 6 5 1 Deoxynucleoside kinase Viral_helicase1 PF01443.18 EAQ89112.1 - 9.8e-06 25.5 0.1 5.2 6.7 0.0 5.4 5 0 0 5 5 5 0 Viral (Superfamily 1) RNA helicase Bac_DnaA PF00308.18 EAQ89112.1 - 2.9e-05 24.0 1.6 7.2 6.4 0.0 5.3 6 0 0 6 6 5 0 Bacterial dnaA protein cobW PF02492.19 EAQ89112.1 - 3.6e-05 23.4 6.0 2.5 7.7 0.1 6.0 6 0 0 6 6 6 1 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.22 EAQ89112.1 - 7e-05 22.1 3.6 13 4.8 0.1 5.8 6 0 0 6 6 5 0 NB-ARC domain TIP49 PF06068.13 EAQ89112.1 - 0.00015 21.1 1.3 2.2 7.4 0.0 4.6 6 0 0 6 6 5 1 TIP49 P-loop domain MobB PF03205.14 EAQ89112.1 - 0.0005 20.0 2.4 32 4.4 0.0 5.8 6 0 0 6 6 6 0 Molybdopterin guanine dinucleotide synthesis protein B VWA PF00092.28 EAQ89112.1 - 0.0007 19.9 0.1 0.002 18.4 0.1 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain DAP3 PF10236.9 EAQ89112.1 - 0.00072 18.8 4.0 0.38 9.9 0.0 5.0 5 0 0 5 5 5 1 Mitochondrial ribosomal death-associated protein 3 APS_kinase PF01583.20 EAQ89112.1 - 0.0016 18.3 0.2 1.3 8.9 0.0 4.6 5 0 0 5 5 4 1 Adenylylsulphate kinase CPT PF07931.12 EAQ89112.1 - 0.0021 17.9 0.3 37 4.1 0.0 5.3 4 1 0 4 4 3 0 Chloramphenicol phosphotransferase-like protein VWA_2 PF13519.6 EAQ89112.1 - 0.0036 17.9 0.1 0.02 15.5 0.1 2.4 1 0 0 1 1 1 1 von Willebrand factor type A domain Ploopntkinase3 PF18751.1 EAQ89112.1 - 0.0042 17.0 0.1 42 4.0 0.0 4.2 4 0 0 4 4 4 0 P-loop Nucleotide Kinase3 G-alpha PF00503.20 EAQ89112.1 - 0.015 14.5 0.8 8.5 5.4 0.0 4.0 4 0 0 4 4 3 0 G-protein alpha subunit Thymidylate_kin PF02223.17 EAQ89112.1 - 0.022 14.4 8.6 13 5.4 0.0 6.2 7 0 0 7 7 6 0 Thymidylate kinase Septin PF00735.18 EAQ89112.1 - 0.026 13.8 1.7 12 5.0 0.0 4.4 5 0 0 5 5 4 0 Septin GAF_2 PF13185.6 EAQ89112.1 - 0.043 14.1 0.0 2.7 8.3 0.0 3.2 3 0 0 3 3 2 0 GAF domain MeaB PF03308.16 EAQ89112.1 - 0.045 12.7 3.0 2.8 6.8 0.1 3.5 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ATPase PF06745.13 EAQ89112.1 - 0.063 12.6 0.2 52 3.1 0.0 4.5 4 0 0 4 4 4 0 KaiC AAA_21 PF13304.6 EAQ89112.1 - 0.069 13.0 0.2 6.3 6.5 0.1 3.7 4 0 0 4 4 3 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_8 PF12780.7 EAQ89112.1 - 0.072 12.4 0.7 10 5.3 0.0 4.1 4 0 0 4 4 3 0 P-loop containing dynein motor region D4 Cytidylate_kin PF02224.18 EAQ89112.1 - 0.14 11.9 0.9 69 3.1 0.2 4.6 5 0 0 5 5 5 0 Cytidylate kinase DUF87 PF01935.17 EAQ89112.1 - 0.18 11.9 6.7 13 5.7 0.3 5.8 6 0 0 6 6 5 0 Helicase HerA, central domain AAA PF00004.29 EAQ89113.1 - 4.2e-50 169.6 0.0 4.4e-42 143.6 0.0 2.8 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EAQ89113.1 - 7.2e-08 32.1 0.0 1e-06 28.4 0.0 2.5 2 0 0 2 2 2 1 AAA+ lid domain AAA_16 PF13191.6 EAQ89113.1 - 2.7e-07 31.1 0.3 0.00078 19.9 0.3 3.4 2 1 0 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.17 EAQ89113.1 - 5e-07 29.6 0.0 3e-05 23.8 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_2 PF07724.14 EAQ89113.1 - 1.8e-05 24.9 0.0 5.6e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 EAQ89113.1 - 9.7e-05 22.4 0.2 0.012 15.6 0.0 3.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EAQ89113.1 - 0.00057 20.2 0.3 0.054 13.8 0.2 3.7 4 1 0 4 4 2 1 AAA domain RuvB_N PF05496.12 EAQ89113.1 - 0.0013 18.5 0.0 0.032 14.0 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 EAQ89113.1 - 0.0014 18.8 0.5 0.023 14.9 0.0 3.3 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 EAQ89113.1 - 0.005 17.2 0.0 0.029 14.7 0.0 2.2 2 0 0 2 2 2 1 RNA helicase TIP49 PF06068.13 EAQ89113.1 - 0.0087 15.3 0.0 0.022 14.0 0.0 1.6 2 0 0 2 2 2 1 TIP49 P-loop domain NACHT PF05729.12 EAQ89113.1 - 0.0094 15.9 0.3 0.35 10.8 0.0 3.2 3 0 0 3 3 3 1 NACHT domain DUF2890 PF11081.8 EAQ89113.1 - 0.018 15.1 0.6 0.018 15.1 0.6 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2890) AAA_18 PF13238.6 EAQ89113.1 - 0.019 15.5 3.2 0.035 14.6 0.0 3.1 4 0 0 4 4 2 0 AAA domain Mg_chelatase PF01078.21 EAQ89113.1 - 0.02 14.3 0.3 0.14 11.5 0.1 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Parvo_NS1 PF01057.17 EAQ89113.1 - 0.025 13.7 0.0 0.2 10.7 0.0 2.0 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AFG1_ATPase PF03969.16 EAQ89113.1 - 0.054 12.4 0.0 2 7.2 0.0 2.3 2 0 0 2 2 2 0 AFG1-like ATPase AAA_3 PF07726.11 EAQ89113.1 - 0.054 13.4 0.0 0.4 10.5 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Bromodomain PF00439.25 EAQ89113.1 - 0.064 13.3 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Bromodomain AAA_28 PF13521.6 EAQ89113.1 - 0.066 13.5 0.0 0.21 11.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EAQ89113.1 - 0.066 12.7 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Sigma54_activ_2 PF14532.6 EAQ89113.1 - 0.085 13.0 0.0 1.6 8.8 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain Torsin PF06309.11 EAQ89113.1 - 0.099 12.8 0.0 1.7 8.7 0.0 2.3 2 0 0 2 2 2 0 Torsin AAA_14 PF13173.6 EAQ89113.1 - 0.1 12.6 0.0 0.23 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 EAQ89113.1 - 0.11 12.2 0.0 3.4 7.4 0.0 2.7 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_11 PF13086.6 EAQ89113.1 - 0.64 9.8 0.0 0.64 9.8 0.0 3.5 2 1 0 2 2 1 0 AAA domain RNA_pol_I_A49 PF06870.12 EAQ89114.1 - 3.6e-77 259.8 0.0 5.8e-61 206.5 0.0 2.1 2 0 0 2 2 2 2 A49-like RNA polymerase I associated factor adh_short PF00106.25 EAQ89115.1 - 3.1e-17 62.7 0.0 5e-17 62.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EAQ89115.1 - 4.2e-14 52.7 0.0 1.2e-13 51.2 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase BCNT PF07572.12 EAQ89116.1 - 2.5e-22 78.7 1.8 4.8e-22 77.8 1.8 1.5 1 0 0 1 1 1 1 Bucentaur or craniofacial development WD40 PF00400.32 EAQ89118.1 - 3.3e-13 49.9 11.0 0.0083 17.0 0.2 5.7 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAQ89118.1 - 0.00011 22.4 0.0 1.6 9.1 0.0 3.7 2 2 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain TFIIF_alpha PF05793.12 EAQ89118.1 - 0.0045 15.7 2.0 0.0063 15.2 2.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) eIF2A PF08662.11 EAQ89118.1 - 0.0086 16.0 0.0 1 9.2 0.0 3.4 1 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.11 EAQ89118.1 - 0.17 10.6 0.0 0.32 9.7 0.0 1.4 1 0 0 1 1 1 0 Nup133 N terminal like SNF2_N PF00176.23 EAQ89119.1 - 1.3e-54 185.2 0.4 1.3e-54 185.2 0.4 2.7 4 1 0 4 4 4 1 SNF2 family N-terminal domain HSA PF07529.13 EAQ89119.1 - 4.1e-18 65.5 11.1 4.1e-18 65.5 11.1 4.4 3 1 1 4 4 4 1 HSA QLQ PF08880.11 EAQ89119.1 - 2.9e-12 46.1 0.4 2.9e-12 46.1 0.4 3.1 3 0 0 3 3 3 1 QLQ ResIII PF04851.15 EAQ89119.1 - 3.2e-11 43.5 0.0 3.2e-11 43.5 0.0 2.6 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit Bromodomain PF00439.25 EAQ89120.1 - 1.8e-19 69.5 0.0 4.2e-19 68.4 0.0 1.6 1 0 0 1 1 1 1 Bromodomain Helicase_C PF00271.31 EAQ89120.1 - 4.4e-15 56.0 0.0 8e-15 55.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SnAC PF14619.6 EAQ89120.1 - 1.2e-13 51.4 0.3 1.2e-13 51.4 0.3 2.4 2 0 0 2 2 2 1 Snf2-ATP coupling, chromatin remodelling complex RBR PF17208.3 EAQ89120.1 - 1.4 9.6 17.0 0.2 12.4 9.0 2.8 1 1 1 2 2 2 0 RNA binding Region Zip PF02535.22 EAQ89121.1 - 3.1e-09 36.5 0.5 3.5e-09 36.3 0.5 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter TauE PF01925.19 EAQ89121.1 - 0.023 14.4 0.8 0.047 13.3 0.2 1.5 1 1 0 1 1 1 0 Sulfite exporter TauE/SafE Tim17 PF02466.19 EAQ89121.1 - 0.073 13.4 1.5 0.23 11.9 0.6 2.1 1 1 1 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family Endonuclease_NS PF01223.23 EAQ89122.1 - 9.9e-67 225.1 0.0 1.2e-66 224.8 0.0 1.0 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease WD40 PF00400.32 EAQ89123.1 - 3.4e-29 100.5 26.1 4.6e-05 24.1 0.0 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAQ89123.1 - 1.6e-11 44.4 0.0 1.6 9.0 0.0 6.0 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 EAQ89123.1 - 0.024 13.4 0.0 0.043 12.6 0.0 1.3 1 0 0 1 1 1 0 Nup133 N terminal like eIF2A PF08662.11 EAQ89123.1 - 0.097 12.5 0.0 4.1 7.2 0.0 2.4 1 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 EAQ89123.1 - 0.32 9.9 0.2 16 4.3 0.0 2.9 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein MBOAT PF03062.19 EAQ89124.1 - 5.2e-21 75.4 16.3 7.9e-21 74.8 16.3 1.3 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 EAQ89124.1 - 0.00042 20.5 3.8 0.0012 19.0 3.8 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family ICMT PF04140.14 EAQ89125.1 - 8.6e-27 93.4 0.7 1.7e-26 92.5 0.7 1.5 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 EAQ89125.1 - 1.7e-10 41.2 2.3 1.7e-10 41.2 2.3 2.4 3 0 0 3 3 3 2 Phospholipid methyltransferase NnrU PF07298.11 EAQ89125.1 - 0.0042 16.6 8.7 0.0069 15.9 8.0 1.8 1 1 0 1 1 1 1 NnrU protein DUF1295 PF06966.12 EAQ89125.1 - 0.031 13.8 2.1 0.044 13.3 2.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1295) Tmemb_170 PF10190.9 EAQ89126.1 - 1.1e-12 48.3 4.4 1.3e-12 48.0 4.4 1.1 1 0 0 1 1 1 1 Putative transmembrane protein 170 SDA1 PF05285.12 EAQ89128.1 - 0.013 15.0 1.5 0.023 14.1 1.5 1.5 1 1 0 1 1 1 0 SDA1 DUF2057 PF09829.9 EAQ89128.1 - 0.48 10.6 2.6 0.9 9.7 2.6 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) zf-C2H2 PF00096.26 EAQ89129.1 - 2.7e-14 52.7 20.2 0.00024 21.4 0.1 7.1 7 0 0 7 7 7 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EAQ89129.1 - 1.4e-07 31.6 13.6 0.18 12.3 0.1 6.5 6 0 0 6 6 6 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 EAQ89129.1 - 3.9e-06 27.2 29.7 0.19 12.7 0.1 7.3 8 0 0 8 8 7 3 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 EAQ89129.1 - 0.00063 19.9 7.0 0.0026 17.9 0.2 3.0 3 1 0 3 3 3 1 Aberrant zinc-finger zf-C2H2_11 PF16622.5 EAQ89129.1 - 0.00068 19.3 10.5 1.7 8.5 0.0 5.8 6 0 0 6 6 6 1 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 EAQ89129.1 - 0.0017 18.6 7.4 0.63 10.4 0.3 5.9 7 0 0 7 7 7 1 Zinc-finger double-stranded RNA-binding DUF4187 PF13821.6 EAQ89129.1 - 0.0023 17.7 0.2 0.01 15.6 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4187) zf-C2H2_3rep PF18868.1 EAQ89129.1 - 0.071 13.8 5.0 0.52 11.0 0.3 3.3 1 1 1 3 3 3 0 Zinc finger C2H2-type, 3 repeats zf_ZIC PF18366.1 EAQ89129.1 - 0.11 12.6 2.6 12 6.1 0.0 4.1 5 0 0 5 5 5 0 Zic proteins zinc finger domain FOXP-CC PF16159.5 EAQ89129.1 - 0.15 12.7 0.2 0.15 12.7 0.2 4.5 4 1 1 5 5 5 0 FOXP coiled-coil domain zf_C2H2_ZHX PF18387.1 EAQ89129.1 - 0.28 10.8 4.7 7.5 6.3 0.1 3.1 3 0 0 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-met PF12874.7 EAQ89129.1 - 0.44 11.0 11.6 0.5 10.8 0.2 4.3 6 0 0 6 6 6 0 Zinc-finger of C2H2 type RNA_pol_Rpb6 PF01192.22 EAQ89130.1 - 7.4e-17 61.0 0.3 1.8e-16 59.8 0.1 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb6 WSC PF01822.19 EAQ89131.1 - 1.9e-33 114.5 27.4 1.2e-18 67.1 10.3 4.5 4 0 0 4 4 4 2 WSC domain PCI PF01399.27 EAQ89132.1 - 7.3e-09 36.1 0.4 6.2e-08 33.1 0.1 2.7 2 0 0 2 2 2 1 PCI domain G-gamma PF00631.22 EAQ89133.1 - 5.4e-25 87.2 0.0 6.9e-25 86.8 0.0 1.1 1 0 0 1 1 1 1 GGL domain Rdx PF10262.9 EAQ89134.1 - 3.2e-33 113.7 0.0 5e-33 113.1 0.0 1.3 1 0 0 1 1 1 1 Rdx family Metallophos PF00149.28 EAQ89135.1 - 3.9e-40 138.5 0.1 5.1e-40 138.1 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EAQ89135.1 - 3.2e-23 81.9 1.8 4.6e-23 81.4 1.0 1.7 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain zf-HC5HC2H_2 PF13832.6 EAQ89137.1 - 5.6e-33 113.4 8.1 5.6e-33 113.4 8.1 2.4 2 0 0 2 2 2 1 PHD-zinc-finger like domain EPL1 PF10513.9 EAQ89137.1 - 5e-30 105.0 0.1 1.5e-29 103.4 0.0 1.8 2 0 0 2 2 2 1 Enhancer of polycomb-like zf-HC5HC2H PF13771.6 EAQ89137.1 - 2.7e-25 88.4 7.8 2.7e-25 88.4 7.8 2.8 3 0 0 3 3 3 2 PHD-like zinc-binding domain PHD_2 PF13831.6 EAQ89137.1 - 2.6e-14 52.5 1.9 2.6e-14 52.5 1.9 2.5 2 0 0 2 2 2 1 PHD-finger PHD PF00628.29 EAQ89137.1 - 9.7e-09 35.0 9.5 9.7e-09 35.0 9.5 2.8 2 0 0 2 2 2 1 PHD-finger zf-PHD-like PF15446.6 EAQ89137.1 - 0.016 14.9 1.8 0.016 14.9 1.8 2.3 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain LRR_8 PF13855.6 EAQ89138.1 - 1.3e-13 50.5 5.3 1.2e-08 34.6 3.9 2.9 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 EAQ89138.1 - 3.4e-11 43.2 3.9 0.0017 18.8 2.5 3.7 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EAQ89138.1 - 0.00023 21.3 5.2 25 5.9 0.1 5.8 5 1 0 5 5 5 1 Leucine Rich Repeat LRR_9 PF14580.6 EAQ89138.1 - 0.0069 15.9 3.3 0.028 13.9 1.4 2.4 2 1 1 3 3 3 2 Leucine-rich repeat LRR_6 PF13516.6 EAQ89138.1 - 0.022 14.8 7.2 24 5.3 0.7 4.8 4 0 0 4 4 4 0 Leucine Rich repeat Biotin_lipoyl PF00364.22 EAQ89142.1 - 9.7e-21 73.4 0.9 1.9e-20 72.4 0.9 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 EAQ89142.1 - 7.8e-10 38.9 0.2 3.2e-09 37.0 0.1 2.1 2 0 0 2 2 2 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 EAQ89142.1 - 0.001 18.8 0.1 0.007 16.2 0.0 2.4 2 0 0 2 2 2 1 Biotin-lipoyl like HlyD_3 PF13437.6 EAQ89142.1 - 0.026 15.2 0.3 1.3 9.7 0.0 2.7 1 1 1 2 2 2 0 HlyD family secretion protein CoA_transf_3 PF02515.17 EAQ89143.1 - 1.5e-35 123.0 0.1 5.9e-34 117.8 0.0 2.2 2 0 0 2 2 2 2 CoA-transferase family III UPF0262 PF06793.12 EAQ89143.1 - 0.12 12.5 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0262) AbiH PF14253.6 EAQ89143.1 - 0.26 11.1 0.1 0.41 10.5 0.1 1.1 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH Fungal_trans PF04082.18 EAQ89145.1 - 1.3e-24 86.7 0.0 2.9e-24 85.6 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Dioxygenase_C PF00775.21 EAQ89146.1 - 9.3e-50 168.6 0.0 1.5e-49 167.9 0.0 1.3 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 EAQ89146.1 - 2.2e-26 91.5 0.1 3.2e-26 91.0 0.1 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 EAQ89146.1 - 8.3e-05 22.8 0.0 0.00035 20.8 0.0 2.0 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain OPT PF03169.15 EAQ89147.1 - 4.3e-71 240.4 17.9 4.9e-71 240.2 17.9 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein OPT PF03169.15 EAQ89148.1 - 1.2e-65 222.4 13.5 1.5e-65 222.1 13.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Ubiq_cyt_C_chap PF03981.12 EAQ89149.1 - 9.2e-37 126.3 1.4 3.5e-36 124.4 1.4 2.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone Ketoacyl-synt_C PF02801.22 EAQ89149.1 - 2.4e-30 105.0 1.2 2.4e-30 105.0 1.2 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain ketoacyl-synt PF00109.26 EAQ89149.1 - 1.3e-29 103.5 11.3 3.6e-10 39.9 0.0 4.4 3 1 1 4 4 4 4 Beta-ketoacyl synthase, N-terminal domain Thiolase_C PF02803.18 EAQ89149.1 - 0.007 16.0 2.7 0.0092 15.6 0.4 2.4 2 1 0 2 2 2 1 Thiolase, C-terminal domain DHFR_1 PF00186.19 EAQ89150.1 - 2e-09 37.4 0.0 0.00029 20.6 0.0 2.1 2 0 0 2 2 2 2 Dihydrofolate reductase Pex14_N PF04695.13 EAQ89150.1 - 0.078 13.6 5.6 0.1 13.2 5.6 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Med13_C PF06333.12 EAQ89150.1 - 0.099 11.9 5.0 0.11 11.7 5.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain DUF908 PF06012.12 EAQ89150.1 - 1.9 7.8 4.5 2.2 7.6 4.5 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Orthopox_A5L PF06193.11 EAQ89150.1 - 3.1 7.2 14.8 4.1 6.8 14.8 1.2 1 0 0 1 1 1 0 Orthopoxvirus A5L protein-like TPR_2 PF07719.17 EAQ89151.1 - 1.7e-08 33.9 20.5 0.016 15.3 0.5 6.5 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 EAQ89151.1 - 1.7e-07 30.7 5.5 0.48 10.3 0.0 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 EAQ89151.1 - 1e-06 29.0 33.1 0.017 15.9 0.4 7.7 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 EAQ89151.1 - 0.00011 22.6 10.0 0.046 14.2 0.1 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 EAQ89151.1 - 0.00038 20.7 12.8 4.9 7.5 0.7 6.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 EAQ89151.1 - 0.0034 17.6 4.5 0.21 12.1 0.1 5.0 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 EAQ89151.1 - 0.0074 16.9 29.1 2.1 9.1 3.8 7.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 EAQ89151.1 - 0.0094 16.1 7.6 0.14 12.5 0.1 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 EAQ89151.1 - 0.014 15.4 10.7 8.3 6.7 0.2 5.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 EAQ89151.1 - 0.13 13.0 9.3 2.6 8.9 0.6 4.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 EAQ89151.1 - 8.9 6.5 18.3 5.3 7.3 0.1 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat RIX1 PF08167.12 EAQ89152.1 - 1.7e-56 190.9 5.2 1.6e-55 187.7 0.1 2.3 2 0 0 2 2 2 2 rRNA processing/ribosome biogenesis DUF4587 PF15248.6 EAQ89152.1 - 0.013 16.2 2.0 0.057 14.2 1.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4587) Glyco_hydro_16 PF00722.21 EAQ89155.1 - 6e-08 32.4 0.3 8.6e-08 31.8 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Prok-E2_E PF14462.6 EAQ89155.1 - 0.11 12.4 0.5 0.23 11.3 0.1 1.7 2 0 0 2 2 2 0 Prokaryotic E2 family E Fungal_lectin PF07938.12 EAQ89156.1 - 7.3e-10 38.7 0.1 6.9e-07 29.0 0.1 2.2 1 1 1 2 2 2 2 Fungal fucose-specific lectin RNA_pol_L PF01193.24 EAQ89156.1 - 0.013 15.0 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb3/Rpb11 dimerisation domain Dus PF01207.17 EAQ89157.1 - 1.3e-38 132.9 0.0 1.6e-32 112.8 0.0 2.2 1 1 1 2 2 2 2 Dihydrouridine synthase (Dus) DHO_dh PF01180.21 EAQ89157.1 - 0.015 14.5 0.0 0.023 13.9 0.0 1.2 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase MA3 PF02847.17 EAQ89160.1 - 7.4e-26 90.3 0.0 1.5e-25 89.3 0.0 1.6 1 0 0 1 1 1 1 MA3 domain MIF4G PF02854.19 EAQ89160.1 - 9.4e-11 41.7 1.5 1.8e-10 40.8 1.5 1.5 1 0 0 1 1 1 1 MIF4G domain FAM176 PF14851.6 EAQ89160.1 - 0.79 9.4 4.3 1.8 8.2 4.3 1.5 1 0 0 1 1 1 0 FAM176 family DPM2 PF07297.12 EAQ89161.1 - 4.5e-33 113.4 1.8 5.9e-33 113.0 1.8 1.1 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.12 EAQ89161.1 - 7e-05 22.7 0.8 9.9e-05 22.2 0.8 1.2 1 0 0 1 1 1 1 PIG-P DUF4229 PF14012.6 EAQ89161.1 - 0.017 15.2 1.9 0.017 15.2 1.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) Pex14_N PF04695.13 EAQ89161.1 - 0.019 15.6 0.1 0.029 15.0 0.1 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region LapA_dom PF06305.11 EAQ89161.1 - 0.039 13.8 0.2 0.092 12.6 0.2 1.6 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain COX14 PF14880.6 EAQ89161.1 - 0.59 10.0 0.0 0.59 10.0 0.0 1.9 2 0 0 2 2 2 0 Cytochrome oxidase c assembly SnoaL_4 PF13577.6 EAQ89163.1 - 0.017 15.2 0.1 0.031 14.4 0.1 1.6 1 1 0 1 1 1 0 SnoaL-like domain SnoaL_2 PF12680.7 EAQ89163.1 - 0.039 14.6 0.5 0.11 13.1 0.2 2.0 2 1 0 2 2 2 0 SnoaL-like domain ING PF12998.7 EAQ89164.1 - 0.03 14.9 0.0 0.11 13.1 0.0 2.1 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding Bactofilin PF04519.13 EAQ89165.1 - 2.4e-10 40.5 0.4 1.4e-07 31.7 0.1 2.2 1 1 1 2 2 2 2 Polymer-forming cytoskeletal FapA PF03961.13 EAQ89165.1 - 0.0015 17.2 0.7 0.0027 16.4 0.8 1.4 1 1 0 1 1 1 1 Flagellar Assembly Protein A DUF4428 PF14471.6 EAQ89165.1 - 0.27 11.2 1.8 2.2 8.3 1.8 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4428) zf-C2H2 PF00096.26 EAQ89167.1 - 0.022 15.2 3.2 0.059 13.8 3.2 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EAQ89167.1 - 0.14 12.7 0.8 13 6.5 0.1 2.4 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 EAQ89167.1 - 1.2 10.2 3.7 4.3 8.4 3.7 2.1 1 0 0 1 1 1 0 C2H2-type zinc finger DUF3602 PF12223.8 EAQ89168.1 - 3.2e-07 30.9 18.5 0.00028 21.4 9.5 3.3 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) Ski2_N PF17911.1 EAQ89168.1 - 0.44 10.4 4.4 2.2 8.1 0.3 2.3 1 1 1 2 2 2 0 Ski2 N-terminal region Pam16 PF03656.13 EAQ89169.1 - 6.9e-06 26.1 0.1 8.5e-06 25.8 0.1 1.3 1 1 0 1 1 1 1 Pam16 DnaJ PF00226.31 EAQ89169.1 - 7.5e-05 22.8 0.0 0.00011 22.2 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain DUF3918 PF13056.6 EAQ89169.1 - 0.0046 16.5 1.1 0.0046 16.5 1.1 2.0 3 0 0 3 3 3 1 Protein of unknown function (DUF3918) TMP_2 PF06791.13 EAQ89169.1 - 0.073 12.7 0.1 0.077 12.6 0.1 1.2 1 0 0 1 1 1 0 Prophage tail length tape measure protein DUF4538 PF15061.6 EAQ89169.1 - 0.14 11.9 0.0 0.32 10.8 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4538) Ku PF02735.16 EAQ89171.1 - 1.7e-34 119.3 0.0 3e-34 118.5 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_PK_bind PF08785.11 EAQ89171.1 - 4.6e-34 117.1 0.0 1.1e-33 115.9 0.0 1.7 1 0 0 1 1 1 1 Ku C terminal domain like Ku_N PF03731.15 EAQ89171.1 - 2.3e-14 53.7 0.0 3.6e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain VWA PF00092.28 EAQ89171.1 - 1.9e-05 25.0 0.1 4.8e-05 23.7 0.1 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain Ku_C PF03730.14 EAQ89171.1 - 0.0034 18.0 2.1 0.011 16.4 0.3 2.7 2 1 1 3 3 3 1 Ku70/Ku80 C-terminal arm DUF1295 PF06966.12 EAQ89173.1 - 8.4e-35 120.4 8.7 2.6e-34 118.8 8.7 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) Topoisom_bac PF01131.20 EAQ89174.1 - 1.5e-85 287.7 0.0 3.4e-58 197.6 0.0 3.1 2 1 1 3 3 3 3 DNA topoisomerase Toprim PF01751.22 EAQ89174.1 - 0.00043 20.5 0.0 0.00099 19.3 0.0 1.6 1 0 0 1 1 1 1 Toprim domain Stb3 PF10330.9 EAQ89175.1 - 4.9e-37 125.8 0.0 7.5e-37 125.3 0.0 1.3 1 0 0 1 1 1 1 Putative Sin3 binding protein SET PF00856.28 EAQ89178.1 - 1.3e-07 32.2 0.0 3.1e-07 30.9 0.0 1.7 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.18 EAQ89178.1 - 1.3 9.1 12.5 0.093 12.8 5.8 2.6 2 0 0 2 2 2 0 MYND finger HypA PF01155.19 EAQ89178.1 - 2.1 8.4 4.8 0.32 11.0 0.6 1.7 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn-ribbon_8 PF09723.10 EAQ89178.1 - 3.2 8.0 9.2 0.066 13.3 1.8 2.0 2 0 0 2 2 2 0 Zinc ribbon domain Hydrolase_6 PF13344.6 EAQ89179.1 - 2.1e-23 82.4 0.0 3.6e-23 81.6 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EAQ89179.1 - 1.1e-14 55.2 0.0 1.1e-06 29.1 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EAQ89179.1 - 1.1e-13 51.1 0.1 2.3e-13 50.0 0.1 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.6 EAQ89179.1 - 3.3e-06 27.3 0.0 0.066 13.3 0.0 2.2 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Indigoidine_A PF04227.12 EAQ89179.1 - 0.19 11.1 0.0 7.1 5.9 0.0 2.2 2 0 0 2 2 2 0 Indigoidine synthase A like protein Glucosamine_iso PF01182.20 EAQ89180.1 - 5.8e-70 235.7 0.0 6.5e-70 235.5 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Glyco_hydro_76 PF03663.14 EAQ89181.1 - 6.6e-51 173.9 12.8 8.1e-51 173.7 12.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_127 PF07944.12 EAQ89181.1 - 4.7e-06 25.4 1.2 0.027 13.0 0.2 2.7 2 1 1 3 3 3 2 Beta-L-arabinofuranosidase, GH127 Glyco_hydro_88 PF07470.13 EAQ89181.1 - 8.8e-06 25.0 3.6 0.0021 17.2 0.0 3.2 1 1 1 3 3 3 3 Glycosyl Hydrolase Family 88 C1_2 PF03107.16 EAQ89183.1 - 0.65 10.4 6.4 1.2 9.5 6.4 1.4 1 0 0 1 1 1 0 C1 domain zf-C2H2 PF00096.26 EAQ89185.1 - 2.6e-08 33.9 18.7 1.8e-05 24.9 3.8 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EAQ89185.1 - 1.9e-05 24.9 6.8 4e-05 23.9 3.8 2.7 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 EAQ89185.1 - 4.2e-05 24.0 2.3 4.2e-05 24.0 2.3 3.5 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_6 PF13912.6 EAQ89185.1 - 0.0011 18.9 3.4 0.0017 18.3 1.8 2.1 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EAQ89185.1 - 0.0015 18.8 1.0 0.0015 18.8 1.0 2.2 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 EAQ89185.1 - 0.037 14.6 9.3 0.075 13.7 0.9 3.3 1 1 2 3 3 3 0 FOXP coiled-coil domain zf-met PF12874.7 EAQ89185.1 - 0.065 13.7 0.7 0.34 11.4 0.7 2.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type ARS2 PF04959.13 EAQ89185.1 - 0.33 11.3 10.4 0.02 15.2 3.9 2.3 3 0 0 3 3 3 0 Arsenite-resistance protein 2 zf-TRAF PF02176.18 EAQ89185.1 - 1.1 9.9 7.6 0.1 13.3 2.8 1.8 2 0 0 2 2 2 0 TRAF-type zinc finger zf-C2H2_8 PF15909.5 EAQ89185.1 - 5.5 7.4 11.3 0.19 12.1 4.2 2.1 2 0 0 2 2 2 0 C2H2-type zinc ribbon DUF629 PF04780.12 EAQ89185.1 - 6.2 5.2 7.3 7.8 4.9 1.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF629) zf-C2H2_2 PF12756.7 EAQ89185.1 - 8.4 6.8 9.5 3.8 7.9 4.8 2.5 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zinc_ribbon_16 PF17034.5 EAQ89186.1 - 2.8e-19 69.6 3.6 6.2e-19 68.4 3.6 1.6 1 0 0 1 1 1 1 Zinc-ribbon like family Zn_ribbon_17 PF17120.5 EAQ89186.1 - 7.1e-06 25.5 4.2 7.1e-06 25.5 4.2 2.4 3 0 0 3 3 3 1 Zinc-ribbon, C4HC2 type zf-RING_2 PF13639.6 EAQ89186.1 - 0.21 11.9 10.2 0.23 11.8 3.9 3.3 3 0 0 3 3 3 0 Ring finger domain zf-rbx1 PF12678.7 EAQ89186.1 - 2.2 8.6 7.9 0.088 13.1 1.3 2.1 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-ribbon_3 PF13248.6 EAQ89186.1 - 5 6.7 7.8 51 3.5 0.0 3.4 3 0 0 3 3 3 0 zinc-ribbon domain DZR PF12773.7 EAQ89186.1 - 7.6 6.7 8.6 1e+02 3.1 6.3 3.1 2 1 0 2 2 2 0 Double zinc ribbon Efg1 PF10153.9 EAQ89187.1 - 3.3e-33 114.5 6.4 3.3e-33 114.5 6.4 1.8 2 0 0 2 2 2 1 rRNA-processing protein Efg1 DUF1688 PF07958.11 EAQ89187.1 - 0.21 10.2 2.0 0.29 9.8 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1688) PepSY_TM_like_2 PF16357.5 EAQ89187.1 - 0.25 11.3 0.2 0.45 10.4 0.2 1.4 1 1 0 1 1 1 0 Putative PepSY_TM-like Presenilin PF01080.17 EAQ89187.1 - 1.5 7.5 2.7 2.8 6.6 2.7 1.4 1 0 0 1 1 1 0 Presenilin MDM1 PF15501.6 EAQ89189.1 - 0.0023 17.2 1.0 0.0032 16.7 1.0 1.1 1 0 0 1 1 1 1 Nuclear protein MDM1 Pox_Ag35 PF03286.14 EAQ89189.1 - 2 8.1 7.2 3.6 7.3 7.2 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein PTS_2-RNA PF01885.16 EAQ89190.1 - 3.4e-62 209.7 0.0 4e-62 209.5 0.0 1.0 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family DSPc PF00782.20 EAQ89194.1 - 5.3e-23 81.3 0.0 4.6e-21 75.0 0.0 2.2 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EAQ89194.1 - 0.0032 17.1 0.0 0.0049 16.5 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 EAQ89194.1 - 0.21 11.9 0.0 0.39 11.0 0.0 1.4 1 0 0 1 1 1 0 Rit1 DUSP-like domain UAA PF08449.11 EAQ89195.1 - 8e-43 146.8 10.0 1.6e-42 145.8 10.0 1.4 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 EAQ89195.1 - 1.1e-10 41.8 25.8 2.7e-05 24.3 8.2 3.5 3 1 0 3 3 3 3 EamA-like transporter family Nuc_sug_transp PF04142.15 EAQ89195.1 - 1.7e-05 24.2 2.0 0.04 13.1 0.2 2.2 2 0 0 2 2 2 2 Nucleotide-sugar transporter TPT PF03151.16 EAQ89195.1 - 0.00056 19.3 7.0 0.063 12.6 0.2 2.2 2 0 0 2 2 2 2 Triose-phosphate Transporter family CRT-like PF08627.10 EAQ89195.1 - 0.0019 17.2 3.7 0.16 10.9 0.1 2.2 2 0 0 2 2 2 2 CRT-like, chloroquine-resistance transporter-like KH_1 PF00013.29 EAQ89196.1 - 3.5e-41 138.9 11.4 6e-17 61.2 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 EAQ89196.1 - 1.8e-10 40.5 10.7 0.0063 16.3 0.5 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 EAQ89196.1 - 1.2e-08 34.7 5.8 0.014 15.2 0.3 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 EAQ89196.1 - 3.1e-05 24.0 5.6 0.12 12.5 0.1 3.3 3 0 0 3 3 3 3 NusA-like KH domain MOEP19 PF16005.5 EAQ89196.1 - 0.0029 17.5 0.0 6.2 6.9 0.0 3.0 3 0 0 3 3 3 2 KH-like RNA-binding domain LRR_6 PF13516.6 EAQ89198.1 - 6.9e-09 35.1 8.8 0.031 14.3 0.0 6.6 7 0 0 7 7 7 3 Leucine Rich repeat F-box-like PF12937.7 EAQ89198.1 - 2.7e-08 33.5 0.0 9.3e-07 28.7 0.0 2.6 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EAQ89198.1 - 1.9e-05 24.4 0.3 5.5e-05 22.9 0.1 2.0 2 0 0 2 2 2 1 F-box domain LRR_1 PF00560.33 EAQ89198.1 - 0.0018 18.5 9.0 2.5 9.0 0.1 6.4 7 0 0 7 7 7 1 Leucine Rich Repeat p47_phox_C PF08944.11 EAQ89198.1 - 0.091 12.2 0.2 0.2 11.1 0.2 1.5 1 0 0 1 1 1 0 NADPH oxidase subunit p47Phox, C terminal domain PRANC PF09372.10 EAQ89198.1 - 0.19 12.1 0.0 0.57 10.5 0.0 1.8 2 0 0 2 2 2 0 PRANC domain DUF5308 PF17233.2 EAQ89198.1 - 0.65 10.2 5.2 0.38 11.0 2.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5308) Pkinase PF00069.25 EAQ89199.1 - 2e-56 191.3 0.0 2.9e-56 190.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ89199.1 - 1.3e-19 70.5 0.0 2e-19 69.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAQ89199.1 - 1.1e-07 31.5 0.0 2.9e-07 30.1 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 EAQ89199.1 - 6.7e-05 22.9 0.3 0.003 17.5 0.1 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EAQ89199.1 - 8.2e-05 22.1 0.1 0.00018 20.9 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EAQ89199.1 - 0.00018 20.6 0.0 0.00031 19.8 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 EAQ89199.1 - 0.0034 17.0 0.1 0.0063 16.1 0.1 1.3 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 EAQ89199.1 - 0.004 16.0 0.4 0.0089 14.8 0.4 1.5 1 1 0 1 1 1 1 Fungal protein kinase STE3 PF02076.15 EAQ89200.1 - 2.5e-54 184.5 20.9 3e-52 177.7 18.7 2.1 1 1 1 2 2 2 2 Pheromone A receptor DUF1980 PF09323.10 EAQ89200.1 - 0.0057 16.6 1.4 1.3 8.9 0.1 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF1980) DUF3169 PF11368.8 EAQ89200.1 - 0.0078 15.8 2.3 0.0078 15.8 2.3 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3169) 7tm_1 PF00001.21 EAQ89200.1 - 0.15 11.3 14.9 0.29 10.4 14.9 1.4 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Pex24p PF06398.11 EAQ89200.1 - 7.6 5.4 7.3 31 3.4 5.3 2.4 2 1 0 2 2 2 0 Integral peroxisomal membrane peroxin GIDA PF01134.22 EAQ89201.1 - 2.2e-155 517.6 0.0 2.7e-155 517.3 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 EAQ89201.1 - 5.2e-65 219.5 0.0 7.2e-65 219.1 0.0 1.2 1 0 0 1 1 1 1 GidA associated domain SSB PF00436.25 EAQ89201.1 - 1.3e-16 60.5 0.0 2.3e-16 59.7 0.0 1.5 1 0 0 1 1 1 1 Single-strand binding protein family Pyr_redox_2 PF07992.14 EAQ89201.1 - 7.1e-05 22.2 0.7 0.00016 21.0 0.7 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EAQ89201.1 - 0.00027 20.4 4.4 0.00027 20.4 4.4 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EAQ89201.1 - 0.00031 20.0 2.2 0.00082 18.6 2.2 1.8 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 EAQ89201.1 - 0.0075 15.6 0.4 0.017 14.4 0.4 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 EAQ89201.1 - 0.029 13.1 1.2 0.14 10.8 0.8 2.0 2 0 0 2 2 2 0 HI0933-like protein CDP-OH_P_transf PF01066.21 EAQ89202.1 - 1.7e-13 51.1 1.4 1.7e-13 51.1 1.4 2.3 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Gti1_Pac2 PF09729.9 EAQ89203.1 - 2.1e-09 37.8 0.0 1.2e-06 28.8 0.0 2.1 1 1 1 2 2 2 2 Gti1/Pac2 family Tyr-DNA_phospho PF06087.12 EAQ89204.1 - 2.6e-79 267.1 0.0 3.7e-79 266.6 0.0 1.2 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.6 EAQ89204.1 - 0.0001 22.2 0.0 0.021 14.7 0.0 2.4 2 0 0 2 2 2 2 PLD-like domain FAM110_C PF14160.6 EAQ89204.1 - 0.11 13.6 0.1 12 7.0 0.0 2.5 2 0 0 2 2 2 0 Centrosome-associated C terminus UIM PF02809.20 EAQ89204.1 - 0.24 11.4 0.1 0.24 11.4 0.1 2.6 3 0 0 3 3 3 0 Ubiquitin interaction motif UBA2_C PF16195.5 EAQ89204.1 - 0.34 11.6 4.4 0.98 10.1 4.4 1.9 1 1 0 1 1 1 0 SUMO-activating enzyme subunit 2 C-terminus PNRC PF15365.6 EAQ89205.1 - 2.1e-08 33.7 5.2 2.1e-08 33.7 5.2 5.0 4 0 0 4 4 4 1 Proline-rich nuclear receptor coactivator motif zf-rbx1 PF12678.7 EAQ89207.1 - 1.5e-06 28.3 1.9 2.3e-06 27.8 1.9 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 EAQ89207.1 - 6.1e-06 26.2 1.5 7.5e-06 25.9 1.5 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger SPC12 PF06645.13 EAQ89208.1 - 3.1e-30 104.0 0.5 3.9e-30 103.8 0.5 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) ZYG-11_interact PF05884.12 EAQ89208.1 - 0.025 14.0 0.1 0.027 13.9 0.1 1.0 1 0 0 1 1 1 0 Interactor of ZYG-11 DUF3040 PF11239.8 EAQ89208.1 - 0.027 14.7 1.6 0.035 14.4 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) CorA PF01544.18 EAQ89209.1 - 7e-40 137.2 0.0 1.1e-39 136.6 0.0 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein zf-Tim10_DDP PF02953.15 EAQ89210.1 - 5.5e-21 74.0 1.1 7.2e-21 73.6 1.1 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Ribosomal_L23eN PF03939.13 EAQ89211.1 - 8.9e-25 86.7 10.3 8.9e-25 86.7 10.3 2.3 3 0 0 3 3 3 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 EAQ89211.1 - 1.5e-14 54.1 0.3 1.5e-14 54.1 0.3 1.7 2 0 0 2 2 2 1 Ribosomal protein L23 DUF3326 PF11805.8 EAQ89211.1 - 0.016 14.1 0.0 0.018 13.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3326) Bmt2 PF11968.8 EAQ89212.1 - 2.6e-79 266.1 0.0 3.5e-79 265.7 0.0 1.1 1 0 0 1 1 1 1 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 Methyltransf_23 PF13489.6 EAQ89212.1 - 0.0034 17.2 0.0 0.0051 16.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EAQ89212.1 - 0.097 13.4 0.0 0.24 12.2 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Hydrolase_like PF13242.6 EAQ89213.1 - 0.0013 18.7 0.0 0.0026 17.8 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 EAQ89213.1 - 0.0025 18.1 0.0 0.0073 16.6 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EAQ89213.1 - 0.16 12.1 0.0 0.22 11.6 0.0 1.2 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Pkinase PF00069.25 EAQ89214.1 - 2.9e-33 115.4 0.0 4.3e-33 114.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ89214.1 - 5.7e-18 65.1 0.0 8.6e-18 64.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAQ89214.1 - 3.4e-06 26.6 0.0 0.0036 16.7 0.0 2.1 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 EAQ89214.1 - 0.0018 17.7 0.0 0.0034 16.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Aa_trans PF01490.18 EAQ89215.1 - 5e-18 65.0 0.6 2.4e-08 33.1 0.0 2.2 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein DEAD PF00270.29 EAQ89217.1 - 1.3e-18 67.4 0.0 1.6e-17 63.8 0.0 2.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EAQ89217.1 - 5e-15 55.8 0.0 1.2e-14 54.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EAQ89217.1 - 9.5e-05 22.5 0.0 0.00051 20.1 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit CorA PF01544.18 EAQ89218.1 - 0.00014 21.3 1.7 0.00014 21.3 1.7 2.2 2 1 0 2 2 2 1 CorA-like Mg2+ transporter protein Phi-29_GP16_7 PF06720.11 EAQ89218.1 - 0.012 15.5 0.4 0.037 13.9 0.1 1.9 2 0 0 2 2 2 0 Bacteriophage phi-29 early protein GP16.7 Pkinase PF00069.25 EAQ89219.1 - 6.6e-12 45.4 0.0 1.1e-11 44.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ89219.1 - 0.00032 20.1 0.0 0.00064 19.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAQ89219.1 - 0.02 14.2 0.0 0.032 13.6 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Lectin_leg-like PF03388.13 EAQ89220.1 - 3e-31 108.6 0.2 4.1e-20 72.1 0.3 2.1 2 0 0 2 2 2 2 Legume-like lectin family Lectin_legB PF00139.19 EAQ89220.1 - 0.00014 21.5 0.0 0.073 12.6 0.0 2.2 1 1 1 2 2 2 2 Legume lectin domain zf-Tim10_DDP PF02953.15 EAQ89221.1 - 9.7e-22 76.4 0.6 1.2e-21 76.1 0.6 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger TerB_C PF15615.6 EAQ89221.1 - 0.092 13.0 0.1 0.16 12.3 0.1 1.5 1 0 0 1 1 1 0 TerB-C domain PI-PLC-X PF00388.19 EAQ89222.1 - 4.1e-62 208.1 0.0 8.4e-62 207.0 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 EAQ89222.1 - 4.3e-43 146.3 0.0 1e-42 145.1 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain DUF2040 PF09745.9 EAQ89222.1 - 7.1e-38 129.4 15.5 7.1e-38 129.4 15.5 3.3 2 1 0 2 2 2 1 Coiled-coil domain-containing protein 55 (DUF2040) Actin PF00022.19 EAQ89223.1 - 7.5e-26 90.7 0.0 1.4e-16 60.1 0.0 2.8 2 1 0 2 2 2 2 Actin Actin_micro PF17003.5 EAQ89223.1 - 0.032 13.4 0.2 2.4 7.3 0.0 2.3 2 0 0 2 2 2 0 Putative actin-like family MreB_Mbl PF06723.13 EAQ89223.1 - 0.039 12.8 0.0 1.6 7.5 0.0 2.1 2 0 0 2 2 2 0 MreB/Mbl protein DUF4451 PF14616.6 EAQ89225.1 - 1.6e-22 80.0 0.0 3.2e-22 79.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) S-AdoMet_synt_C PF02773.16 EAQ89226.1 - 4.8e-66 221.0 0.7 8.1e-66 220.2 0.1 1.7 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 EAQ89226.1 - 7.3e-44 148.9 0.0 1.3e-43 148.0 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 EAQ89226.1 - 3.2e-42 143.2 0.2 8.7e-42 141.8 0.0 1.8 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain YfcL PF08891.11 EAQ89227.1 - 0.016 15.5 0.3 0.043 14.2 0.0 1.8 2 0 0 2 2 2 0 YfcL protein THF_DHG_CYH PF00763.23 EAQ89228.1 - 6.2e-26 91.0 0.1 9.4e-26 90.4 0.1 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 EAQ89228.1 - 4.8e-14 52.0 0.0 1.1e-08 34.6 0.0 2.5 2 0 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain SBP_bac_5 PF00496.22 EAQ89228.1 - 0.037 13.0 0.4 0.052 12.5 0.4 1.1 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 5 Middle MMS19_N PF14500.6 EAQ89229.1 - 1.1e-35 123.5 0.6 6e-28 98.1 0.0 3.7 4 0 0 4 4 4 2 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.8 EAQ89229.1 - 8.4e-14 51.5 0.0 1.3e-12 47.6 0.0 2.7 2 1 1 3 3 3 1 RNAPII transcription regulator C-terminal DUF3385 PF11865.8 EAQ89229.1 - 0.12 12.2 0.0 1.1 9.2 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF3385) SPC25 PF06703.11 EAQ89230.1 - 7.2e-49 165.7 0.0 9.5e-49 165.3 0.0 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) EMC3_TMCO1 PF01956.16 EAQ89231.1 - 1.1e-27 96.9 3.8 1e-17 64.4 0.9 2.3 2 0 0 2 2 2 2 Integral membrane protein EMC3/TMCO1-like SIL1 PF16782.5 EAQ89233.1 - 4.4e-06 26.1 0.0 8e-06 25.3 0.0 1.4 1 1 0 1 1 1 1 Nucleotide exchange factor SIL1 SET PF00856.28 EAQ89235.1 - 1.8e-11 44.8 0.0 3.6e-10 40.5 0.0 2.4 1 1 0 1 1 1 1 SET domain Ribosomal_S19 PF00203.21 EAQ89236.1 - 4.9e-33 112.9 0.3 7e-33 112.4 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 Glyco_hydro_53 PF07745.13 EAQ89237.1 - 5e-115 384.1 4.6 5.6e-115 383.9 4.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 ADH_zinc_N PF00107.26 EAQ89238.1 - 7.9e-06 25.9 0.0 1.6e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EAQ89238.1 - 0.017 16.2 0.0 0.034 15.2 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase ADH_N PF08240.12 EAQ89238.1 - 0.049 13.5 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain Glutaredoxin PF00462.24 EAQ89239.1 - 2e-12 47.1 0.0 3.8e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin TraF PF13728.6 EAQ89239.1 - 0.035 13.9 0.1 0.14 12.0 0.0 1.9 2 0 0 2 2 2 0 F plasmid transfer operon protein Ribosomal_L21p PF00829.21 EAQ89241.1 - 1.1e-12 48.1 0.0 2.1e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein Pkinase PF00069.25 EAQ89242.1 - 3.6e-18 65.9 0.0 2.3e-10 40.3 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ89242.1 - 7.6e-06 25.4 0.0 7e-05 22.2 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Ribosomal_60s PF00428.19 EAQ89243.1 - 1.9e-27 95.7 11.4 2.1e-27 95.5 11.4 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein EF-hand_14 PF17959.1 EAQ89243.1 - 0.0045 17.3 0.0 0.0068 16.7 0.0 1.3 1 0 0 1 1 1 1 EF-hand domain UBA_6 PF18039.1 EAQ89243.1 - 0.06 13.3 0.8 0.091 12.7 0.1 1.6 2 0 0 2 2 2 0 UBA-like domain Phage-MuB_C PF09077.11 EAQ89243.1 - 0.065 13.1 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Mu B transposition protein, C terminal SPT2 PF08243.11 EAQ89244.1 - 1.6e-08 35.0 32.7 1.6e-08 35.0 32.7 2.7 2 1 0 2 2 2 1 SPT2 chromatin protein Ribosomal_S8e PF01201.22 EAQ89245.1 - 2.1e-25 89.5 2.0 1.9e-24 86.4 0.6 2.3 1 1 0 1 1 1 1 Ribosomal protein S8e IBR PF01485.21 EAQ89246.1 - 1.1e-05 25.5 0.7 1.1e-05 25.5 0.7 2.9 3 0 0 3 3 3 1 IBR domain, a half RING-finger domain zf-C3HC4_2 PF13923.6 EAQ89246.1 - 0.0018 18.1 5.3 0.0018 18.1 5.3 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EAQ89246.1 - 0.0077 16.5 8.2 0.0077 16.5 8.2 2.5 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 EAQ89246.1 - 0.0096 15.9 9.0 0.0096 15.9 9.0 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EAQ89246.1 - 0.048 13.7 12.0 0.11 12.6 12.0 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_11 PF17123.5 EAQ89246.1 - 4.4 7.1 9.9 9 6.2 8.2 2.3 2 0 0 2 2 2 0 RING-like zinc finger HET PF06985.11 EAQ89247.1 - 1.5e-21 77.3 0.0 3.4e-21 76.1 0.0 1.6 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PIF1 PF05970.14 EAQ89249.1 - 9.9e-18 64.4 0.0 3.3e-16 59.4 0.0 2.3 2 0 0 2 2 2 1 PIF1-like helicase NACHT PF05729.12 EAQ89249.1 - 6.1e-10 39.3 0.1 1.3e-09 38.2 0.1 1.6 1 0 0 1 1 1 1 NACHT domain Ank_2 PF12796.7 EAQ89249.1 - 3.9e-09 37.0 0.0 1.5e-08 35.1 0.0 2.1 2 0 0 2 2 1 1 Ankyrin repeats (3 copies) AAA_30 PF13604.6 EAQ89249.1 - 8.4e-09 35.4 0.4 4.3e-05 23.3 0.0 3.6 3 0 0 3 3 3 2 AAA domain Ank PF00023.30 EAQ89249.1 - 2.4e-05 24.5 0.5 0.062 13.8 0.1 4.5 4 0 0 4 4 4 1 Ankyrin repeat AAA_16 PF13191.6 EAQ89249.1 - 2.9e-05 24.5 3.1 4.4e-05 23.9 0.7 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EAQ89249.1 - 0.00044 20.5 0.0 0.0048 17.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain Ank_4 PF13637.6 EAQ89249.1 - 0.0016 19.0 0.0 0.025 15.2 0.0 2.8 1 1 1 2 2 2 1 Ankyrin repeats (many copies) AAA_14 PF13173.6 EAQ89249.1 - 0.0042 17.1 0.0 0.84 9.7 0.0 3.3 2 1 0 2 2 2 1 AAA domain NB-ARC PF00931.22 EAQ89249.1 - 0.018 14.2 0.0 0.076 12.2 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain Ank_5 PF13857.6 EAQ89249.1 - 0.046 14.0 0.0 2 8.9 0.0 2.9 1 1 1 2 2 2 0 Ankyrin repeats (many copies) ATPase_2 PF01637.18 EAQ89249.1 - 0.072 13.0 0.0 0.37 10.7 0.0 2.0 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea FAD_binding_4 PF01565.23 EAQ89249.1 - 0.093 12.5 0.2 11 5.7 0.0 2.9 2 0 0 2 2 2 0 FAD binding domain ResIII PF04851.15 EAQ89249.1 - 0.16 11.9 0.0 0.4 10.7 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Fungal_trans PF04082.18 EAQ89253.1 - 1.6e-10 40.5 0.2 2.8e-10 39.7 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain FAD_binding_3 PF01494.19 EAQ89254.1 - 1.6e-19 70.4 0.0 2.3e-19 69.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 EAQ89254.1 - 5.8e-07 29.4 0.2 0.00058 19.5 0.1 2.1 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EAQ89254.1 - 1.5e-05 24.4 0.0 0.001 18.4 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EAQ89254.1 - 0.00054 20.5 0.1 0.014 15.9 0.1 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EAQ89254.1 - 0.0013 18.9 0.1 0.0034 17.6 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EAQ89254.1 - 0.0033 16.6 0.1 0.005 16.0 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain ApbA PF02558.16 EAQ89254.1 - 0.0095 15.6 0.0 0.019 14.6 0.0 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Trp_halogenase PF04820.14 EAQ89254.1 - 0.037 12.9 0.0 0.43 9.4 0.1 2.0 2 0 0 2 2 2 0 Tryptophan halogenase N2227 PF07942.12 EAQ89255.1 - 2.5e-09 36.7 0.0 4.1e-06 26.2 0.0 2.8 2 1 1 3 3 3 2 N2227-like protein ST7 PF04184.12 EAQ89255.1 - 0.036 12.5 0.1 0.063 11.7 0.1 1.3 1 0 0 1 1 1 0 ST7 protein PMI_typeI PF01238.21 EAQ89255.1 - 0.068 12.3 0.2 6.4 5.9 0.2 2.1 1 1 0 2 2 2 0 Phosphomannose isomerase type I DUF4754 PF15946.5 EAQ89255.1 - 0.17 12.2 0.1 5.1 7.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4754) DUF2284 PF10050.9 EAQ89257.1 - 2.3 7.9 53.4 0.69 9.6 2.2 6.7 6 1 1 7 7 7 0 Predicted metal-binding protein (DUF2284) Y_phosphatase PF00102.27 EAQ89259.1 - 0.23 11.0 0.0 0.32 10.5 0.0 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase K_oxygenase PF13434.6 EAQ89261.1 - 0.0014 17.8 0.0 0.43 9.7 0.0 2.1 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 EAQ89261.1 - 0.17 11.1 0.0 0.28 10.4 0.0 1.2 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.6 EAQ89261.1 - 3.4 7.6 4.6 2.4 8.1 0.2 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding WSC PF01822.19 EAQ89262.1 - 1.2e-60 201.7 45.8 1.6e-18 66.7 5.1 4.1 4 0 0 4 4 4 4 WSC domain Toxin_35 PF10530.9 EAQ89262.1 - 1.1 9.3 15.4 1.1 9.3 0.5 4.3 4 0 0 4 4 4 0 Toxin with inhibitor cystine knot ICK or Knottin scaffold NDC10_II PF16787.5 EAQ89264.1 - 1e-62 212.1 0.1 1.4e-62 211.6 0.1 1.2 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 GCR1_C PF12550.8 EAQ89264.1 - 8.3e-15 54.9 0.0 3.1e-14 53.0 0.0 2.1 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes Pkinase PF00069.25 EAQ89264.1 - 3.9e-06 26.4 0.0 0.0018 17.7 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain PilJ PF13675.6 EAQ89264.1 - 0.057 13.4 2.6 0.13 12.3 1.0 2.3 2 1 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Pkinase_Tyr PF07714.17 EAQ89264.1 - 0.15 11.3 0.0 4.7 6.4 0.0 2.3 1 1 1 2 2 2 0 Protein tyrosine kinase HalX PF08663.10 EAQ89264.1 - 0.15 12.4 1.6 0.4 11.0 1.6 1.7 1 0 0 1 1 1 0 HalX domain zf-C2H2 PF00096.26 EAQ89266.1 - 0.016 15.7 0.4 0.016 15.7 0.4 3.4 3 0 0 3 3 3 0 Zinc finger, C2H2 type Presenilin PF01080.17 EAQ89266.1 - 1 8.0 4.3 1.5 7.5 4.3 1.2 1 0 0 1 1 1 0 Presenilin SelP_N PF04592.14 EAQ89266.1 - 1 8.7 19.8 2 7.7 19.8 1.5 1 0 0 1 1 1 0 Selenoprotein P, N terminal region TFIIA PF03153.13 EAQ89266.1 - 5.1 7.0 20.2 7.2 6.5 20.2 1.3 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SARAF PF06682.12 EAQ89266.1 - 8.9 5.9 13.2 2 8.0 9.3 1.7 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis DUF1970 PF09301.10 EAQ89269.1 - 0.023 14.9 0.7 0.057 13.7 0.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1970) DUF3046 PF11248.8 EAQ89271.1 - 0.18 12.2 3.5 6.2 7.3 0.2 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3046) HLH PF00010.26 EAQ89272.1 - 3.9e-11 42.7 1.2 3.9e-11 42.7 1.2 1.8 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain DUF3106 PF11304.8 EAQ89272.1 - 0.01 16.3 3.2 1.1 9.7 1.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3106) DUF4776 PF16003.5 EAQ89272.1 - 0.094 11.7 0.2 0.12 11.3 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) DUF4705 PF15788.5 EAQ89272.1 - 0.16 12.2 8.8 4.9 7.5 4.0 3.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4705) RRM_1 PF00076.22 EAQ89274.1 - 1.3e-35 121.0 0.0 1.9e-16 59.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EAQ89274.1 - 0.0079 16.3 0.0 2.5 8.3 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif RRM_Rrp7 PF17799.1 EAQ89274.1 - 0.032 14.0 0.0 1.1 9.1 0.0 2.2 2 0 0 2 2 2 0 Rrp7 RRM-like N-terminal domain OB_RNB PF08206.11 EAQ89274.1 - 0.061 13.0 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 Ribonuclease B OB domain TPR_1 PF00515.28 EAQ89275.1 - 3.7e-23 80.3 10.8 1e-07 31.4 0.1 6.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 EAQ89275.1 - 6.8e-22 75.8 15.3 1e-06 28.4 0.2 6.3 7 0 0 7 7 5 4 Tetratricopeptide repeat TPR_14 PF13428.6 EAQ89275.1 - 7e-18 63.8 8.0 6.4e-06 26.6 0.1 6.1 4 1 2 6 6 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 EAQ89275.1 - 1.5e-17 63.0 10.6 1.2e-07 31.3 0.1 4.9 3 2 2 5 5 5 3 TPR repeat TPR_17 PF13431.6 EAQ89275.1 - 8.6e-16 57.1 6.9 0.0022 18.3 0.0 5.3 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.6 EAQ89275.1 - 7.1e-15 55.4 18.2 2.6e-06 28.0 2.6 4.8 4 2 1 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 EAQ89275.1 - 3.2e-14 51.9 4.1 9.4e-05 22.3 0.0 5.3 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 EAQ89275.1 - 1.1e-13 50.1 6.1 0.0064 16.4 0.0 6.8 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 EAQ89275.1 - 3.7e-13 49.8 10.0 0.00045 20.7 4.2 4.7 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_12 PF13424.6 EAQ89275.1 - 8.7e-11 42.0 8.9 0.00052 20.3 1.3 4.7 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_9 PF13371.6 EAQ89275.1 - 2.4e-10 40.4 5.6 0.0024 18.0 0.2 4.0 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_20 PF14561.6 EAQ89275.1 - 1.9e-09 37.7 4.3 0.024 14.9 0.0 4.5 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_6 PF13174.6 EAQ89275.1 - 3.2e-09 36.8 4.3 0.45 11.3 0.2 6.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_15 PF13429.6 EAQ89275.1 - 2.7e-05 23.5 1.2 0.048 12.9 0.5 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EAQ89275.1 - 0.00018 21.7 4.8 0.2 11.9 0.7 2.7 2 1 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_3 PF07720.12 EAQ89275.1 - 0.009 16.0 1.2 4.5 7.4 0.3 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 EAQ89275.1 - 0.016 15.1 0.6 0.016 15.1 0.6 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF1641 PF07849.11 EAQ89275.1 - 0.096 12.6 0.3 0.3 11.0 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1641) BTAD PF03704.17 EAQ89275.1 - 0.28 11.6 5.7 11 6.4 0.5 3.4 2 1 1 3 3 3 0 Bacterial transcriptional activator domain TFIIA PF03153.13 EAQ89275.1 - 0.37 10.7 6.6 0.68 9.9 6.6 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CRISPR_Cse2 PF09485.10 EAQ89275.1 - 0.41 11.2 5.8 0.14 12.6 0.3 2.6 3 0 0 3 3 2 0 CRISPR-associated protein Cse2 (CRISPR_cse2) RNase_T PF00929.24 EAQ89276.1 - 1e-08 35.9 0.0 2.7e-08 34.5 0.0 1.7 1 1 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 EAQ89276.1 - 0.2 11.3 0.0 0.49 10.1 0.0 1.5 1 1 0 1 1 1 0 3'-5' exonuclease DUF1664 PF07889.12 EAQ89277.1 - 1.6e-05 24.9 0.3 0.023 14.7 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 EAQ89277.1 - 0.00012 22.3 0.4 0.0033 17.6 0.0 2.7 1 1 1 2 2 2 1 Fibrinogen alpha/beta chain family Yippee-Mis18 PF03226.14 EAQ89277.1 - 0.00016 21.8 0.3 0.00043 20.5 0.3 1.7 1 1 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Baculo_PEP_C PF04513.12 EAQ89277.1 - 0.0013 18.8 0.3 1.4 9.0 0.0 2.2 1 1 1 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus PspA_IM30 PF04012.12 EAQ89277.1 - 0.0013 18.3 1.1 0.62 9.6 0.2 2.3 1 1 0 2 2 2 2 PspA/IM30 family TolA_bind_tri PF16331.5 EAQ89277.1 - 0.0015 18.6 6.3 0.021 14.9 1.7 3.3 2 1 0 2 2 2 1 TolA binding protein trimerisation GAS PF13851.6 EAQ89277.1 - 0.0032 16.9 0.8 0.33 10.3 0.0 2.2 2 0 0 2 2 2 1 Growth-arrest specific micro-tubule binding Prefoldin_2 PF01920.20 EAQ89277.1 - 0.0033 17.4 1.3 1.6 8.7 0.0 3.2 2 1 1 3 3 3 1 Prefoldin subunit Spc7 PF08317.11 EAQ89277.1 - 0.0033 16.4 0.5 0.35 9.7 0.1 2.2 1 1 1 2 2 2 2 Spc7 kinetochore protein TMF_TATA_bd PF12325.8 EAQ89277.1 - 0.006 16.8 1.3 2.2 8.6 0.0 2.8 1 1 2 3 3 3 1 TATA element modulatory factor 1 TATA binding SlyX PF04102.12 EAQ89277.1 - 0.013 16.1 3.1 0.58 10.8 0.0 3.0 2 1 0 2 2 2 0 SlyX Sec3_C PF09763.9 EAQ89277.1 - 0.017 13.5 0.1 0.26 9.7 0.0 2.0 2 0 0 2 2 2 0 Exocyst complex component Sec3 DapB_N PF01113.20 EAQ89277.1 - 0.019 15.1 0.1 0.032 14.3 0.1 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus HMMR_N PF15905.5 EAQ89277.1 - 0.02 14.4 0.1 0.029 13.8 0.1 1.2 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Filament PF00038.21 EAQ89277.1 - 0.025 14.2 1.8 4.1 6.9 0.3 2.3 1 1 0 2 2 2 0 Intermediate filament protein NPV_P10 PF05531.12 EAQ89277.1 - 0.034 14.6 0.3 3.7 8.1 0.1 2.9 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein CCDC-167 PF15188.6 EAQ89277.1 - 0.038 14.3 1.9 0.63 10.4 0.2 2.5 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 IFT57 PF10498.9 EAQ89277.1 - 0.045 12.7 0.4 4 6.3 0.0 2.1 1 1 0 2 2 2 0 Intra-flagellar transport protein 57 AAA_13 PF13166.6 EAQ89277.1 - 0.063 11.9 0.0 0.083 11.5 0.0 1.1 1 0 0 1 1 1 0 AAA domain DUF2894 PF11445.8 EAQ89277.1 - 0.084 13.3 0.2 0.14 12.6 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2894) Syntaxin-6_N PF09177.11 EAQ89277.1 - 0.12 13.0 0.2 3.2 8.3 0.0 2.4 1 1 1 2 2 2 0 Syntaxin 6, N-terminal KASH_CCD PF14662.6 EAQ89277.1 - 0.12 12.2 0.3 0.36 10.6 0.1 1.9 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH DUF3450 PF11932.8 EAQ89277.1 - 0.12 11.6 1.8 7.3 5.8 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) YabA PF06156.13 EAQ89277.1 - 0.13 12.9 0.3 8.5 7.1 0.0 2.8 1 1 0 2 2 2 0 Initiation control protein YabA HIP1_clath_bdg PF16515.5 EAQ89277.1 - 0.14 12.8 3.1 6.7 7.4 0.1 3.1 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 ATG16 PF08614.11 EAQ89277.1 - 0.14 12.4 3.6 5.7 7.1 0.1 2.4 1 1 0 2 2 2 0 Autophagy protein 16 (ATG16) FlaC_arch PF05377.11 EAQ89277.1 - 0.18 12.2 0.7 22 5.5 0.0 3.2 3 0 0 3 3 2 0 Flagella accessory protein C (FlaC) Tup_N PF08581.10 EAQ89277.1 - 0.22 11.8 1.1 70 3.8 0.0 3.6 2 2 1 4 4 4 0 Tup N-terminal DUF1515 PF07439.11 EAQ89277.1 - 0.23 11.5 1.1 1.3 9.1 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) DUF4200 PF13863.6 EAQ89277.1 - 0.23 11.9 0.8 12 6.4 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) COG2 PF06148.11 EAQ89277.1 - 0.27 11.3 1.7 4 7.5 0.1 2.8 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Golgin_A5 PF09787.9 EAQ89277.1 - 0.32 10.4 2.0 1.1 8.7 1.7 1.7 1 1 1 2 2 2 0 Golgin subfamily A member 5 HrpB7 PF09486.10 EAQ89277.1 - 0.34 11.3 4.2 2.5 8.5 1.5 2.4 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) Prefoldin PF02996.17 EAQ89280.1 - 2e-25 89.0 0.1 2.7e-25 88.6 0.1 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.20 EAQ89280.1 - 0.004 17.1 0.2 1.1 9.3 0.0 2.1 2 0 0 2 2 2 2 Prefoldin subunit DUF1664 PF07889.12 EAQ89280.1 - 0.078 13.0 0.2 0.37 10.9 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF1192 PF06698.11 EAQ89280.1 - 0.15 12.2 0.6 0.4 10.8 0.2 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1192) AAA PF00004.29 EAQ89282.1 - 1.4e-15 57.9 0.0 2.5e-15 57.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_10 PF17872.1 EAQ89282.1 - 4e-12 46.1 0.0 9.6e-12 44.9 0.0 1.6 1 0 0 1 1 1 1 AAA lid domain AAA_16 PF13191.6 EAQ89282.1 - 3.2e-10 40.7 0.9 3.4e-09 37.3 0.0 2.9 3 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 EAQ89282.1 - 5.8e-09 36.3 0.0 1.5e-08 35.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain BAH PF01426.18 EAQ89282.1 - 2.5e-05 24.1 0.0 5.2e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 BAH domain AAA_19 PF13245.6 EAQ89282.1 - 0.00094 19.5 0.0 0.0021 18.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 EAQ89282.1 - 0.0059 16.9 0.0 0.11 12.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 EAQ89282.1 - 0.0074 16.1 0.1 0.1 12.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EAQ89282.1 - 0.024 15.2 0.0 0.065 13.8 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_33 PF13671.6 EAQ89282.1 - 0.049 13.8 0.9 1.2 9.2 0.0 2.7 3 0 0 3 3 3 0 AAA domain ssDBP PF17878.1 EAQ89282.1 - 0.053 13.8 0.1 0.25 11.6 0.0 2.0 2 0 0 2 2 2 0 Single-stranded DNA-binding protein AAA_32 PF13654.6 EAQ89282.1 - 0.091 11.5 0.0 0.16 10.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EAQ89282.1 - 0.14 12.0 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 NACHT domain WD40 PF00400.32 EAQ89283.1 - 8.9e-45 149.8 15.5 1.3e-09 38.5 0.2 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAQ89283.1 - 6.9e-06 26.3 0.3 0.6 10.5 0.0 4.6 1 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EAQ89283.1 - 0.03 13.0 0.8 11 4.5 0.0 3.5 1 1 1 4 4 4 0 Nucleoporin Nup120/160 TMF_TATA_bd PF12325.8 EAQ89284.1 - 7.7e-19 68.0 1.5 7.7e-19 68.0 1.5 7.4 2 2 6 8 8 8 3 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.8 EAQ89284.1 - 2e-17 62.9 13.1 2e-17 62.9 13.1 8.0 4 2 4 8 8 8 3 TATA element modulatory factor 1 DNA binding Tropomyosin_1 PF12718.7 EAQ89284.1 - 0.00067 19.8 16.4 0.00067 19.8 16.4 4.9 3 1 3 6 6 6 2 Tropomyosin like GAS PF13851.6 EAQ89284.1 - 0.0054 16.1 16.1 0.0054 16.1 16.1 5.1 2 1 3 5 5 5 1 Growth-arrest specific micro-tubule binding PKcGMP_CC PF16808.5 EAQ89284.1 - 0.2 11.5 0.1 0.2 11.5 0.1 6.8 5 1 2 7 7 7 0 Coiled-coil N-terminus of cGMP-dependent protein kinase BRE1 PF08647.11 EAQ89284.1 - 0.35 11.0 0.1 0.35 11.0 0.1 6.8 3 2 4 7 7 7 0 BRE1 E3 ubiquitin ligase Ceramidase PF05875.12 EAQ89286.1 - 1.2e-88 297.0 11.4 1.6e-88 296.5 11.4 1.1 1 0 0 1 1 1 1 Ceramidase Prefoldin_2 PF01920.20 EAQ89286.1 - 2e-19 69.5 0.2 3e-19 68.9 0.2 1.3 1 0 0 1 1 1 1 Prefoldin subunit TMF_TATA_bd PF12325.8 EAQ89286.1 - 0.02 15.1 2.0 2.4 8.4 0.0 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF3450 PF11932.8 EAQ89286.1 - 0.17 11.2 3.3 0.59 9.4 1.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Mito_carr PF00153.27 EAQ89288.1 - 2e-46 155.8 3.2 3e-17 62.3 0.0 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF3439 PF11921.8 EAQ89288.1 - 1.4 8.9 6.6 1.9 8.5 0.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Dor1 PF04124.12 EAQ89289.1 - 9.2e-61 205.4 7.4 1.6e-57 194.8 4.9 3.6 2 2 1 3 3 3 3 Dor1-like family Latarcin PF10279.9 EAQ89289.1 - 0.13 12.7 0.0 0.99 9.9 0.0 2.2 2 1 0 2 2 2 0 Latarcin precursor COG5 PF10392.9 EAQ89289.1 - 1.6 8.9 8.0 0.69 10.1 3.8 2.4 2 0 0 2 2 2 0 Golgi transport complex subunit 5 TRAM_LAG1_CLN8 PF03798.16 EAQ89292.1 - 1.2e-52 178.5 8.9 1.7e-52 178.0 8.9 1.2 1 0 0 1 1 1 1 TLC domain SHD1 PF03983.12 EAQ89293.1 - 2.3e-33 113.8 0.0 3.9e-33 113.1 0.0 1.4 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_1 PF00018.28 EAQ89293.1 - 7.1e-28 96.0 4.8 7e-11 41.6 0.1 4.4 4 0 0 4 4 4 3 SH3 domain SH3_9 PF14604.6 EAQ89293.1 - 1.2e-27 95.5 6.9 6.7e-10 38.7 0.4 3.8 4 0 0 4 4 4 3 Variant SH3 domain SH3_2 PF07653.17 EAQ89293.1 - 5.1e-20 70.9 0.2 5.2e-06 26.1 0.0 4.3 4 0 0 4 4 4 4 Variant SH3 domain SAM_4 PF18017.1 EAQ89293.1 - 8.9e-05 22.4 0.0 0.0002 21.2 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_3 PF08239.11 EAQ89293.1 - 0.00019 21.6 4.0 0.41 11.0 0.5 3.3 3 0 0 3 3 3 2 Bacterial SH3 domain A_deaminase PF00962.22 EAQ89294.1 - 4.5e-119 397.6 0.1 6.2e-119 397.2 0.1 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase UAA PF08449.11 EAQ89295.1 - 8.8e-107 356.8 5.4 1.1e-106 356.4 5.4 1.0 1 0 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.15 EAQ89295.1 - 2.2e-05 23.8 0.1 2.2e-05 23.8 0.1 1.8 2 0 0 2 2 2 1 Nucleotide-sugar transporter Tetraspanin PF00335.20 EAQ89295.1 - 0.0086 15.8 2.5 0.0086 15.8 2.5 2.2 2 1 0 2 2 2 1 Tetraspanin family EamA PF00892.20 EAQ89295.1 - 0.035 14.3 27.0 0.83 9.8 11.8 3.6 2 2 1 3 3 3 0 EamA-like transporter family Potex_coat PF06184.11 EAQ89295.1 - 0.14 11.7 0.0 0.33 10.5 0.0 1.6 2 0 0 2 2 2 0 Potexvirus coat protein DUF4293 PF14126.6 EAQ89295.1 - 0.47 10.7 5.3 0.1 12.8 0.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) Sybindin PF04099.12 EAQ89296.1 - 9.9e-52 174.7 0.0 1.1e-51 174.5 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 EAQ89296.1 - 1.1e-08 35.3 0.1 2.3e-08 34.2 0.1 1.5 2 0 0 2 2 2 1 Sedlin, N-terminal conserved region VWA_2 PF13519.6 EAQ89297.1 - 5.4e-25 88.1 0.2 1.7e-24 86.5 0.0 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.28 EAQ89297.1 - 1.3e-07 32.0 0.2 1.7e-07 31.6 0.2 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.14 EAQ89297.1 - 1.2e-05 25.3 0.0 1.7e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like UIM PF02809.20 EAQ89297.1 - 0.0084 16.0 1.1 0.021 14.7 1.1 1.7 1 0 0 1 1 1 1 Ubiquitin interaction motif Nbl1_Borealin_N PF10444.9 EAQ89298.1 - 1.3e-19 69.6 3.2 1.7e-19 69.2 2.2 1.7 2 0 0 2 2 2 1 Nbl1 / Borealin N terminal SUI1 PF01253.22 EAQ89299.1 - 1.1e-25 89.9 0.5 3.2e-25 88.5 0.5 1.7 1 0 0 1 1 1 1 Translation initiation factor SUI1 Img2 PF05046.14 EAQ89299.1 - 0.028 14.7 0.3 0.062 13.6 0.1 1.8 2 1 0 2 2 2 0 Mitochondrial large subunit ribosomal protein (Img2) TnpV PF14198.6 EAQ89299.1 - 0.075 13.0 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Transposon-encoded protein TnpV MscS_TM PF12794.7 EAQ89299.1 - 0.6 8.9 2.4 0.8 8.5 2.4 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Methyltransf_11 PF08241.12 EAQ89300.1 - 4.4e-12 46.5 0.0 9.6e-12 45.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAQ89300.1 - 1.9e-05 25.3 0.0 4.4e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAQ89300.1 - 0.022 14.6 0.0 0.044 13.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 EAQ89300.1 - 0.029 15.1 0.0 0.081 13.7 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Peptidase_A24 PF01478.18 EAQ89301.1 - 0.12 12.8 0.0 0.2 12.1 0.0 1.2 1 0 0 1 1 1 0 Type IV leader peptidase family zf-C2H2 PF00096.26 EAQ89301.1 - 4.8 7.8 24.6 4.3 8.0 0.5 6.3 6 0 0 6 6 6 0 Zinc finger, C2H2 type YppG PF14179.6 EAQ89303.1 - 0.0082 16.8 6.2 0.0084 16.8 6.2 1.2 1 0 0 1 1 1 1 YppG-like protein Spt20 PF12090.8 EAQ89303.1 - 0.053 13.1 3.4 0.054 13.1 3.4 1.1 1 0 0 1 1 1 0 Spt20 family CAP_N PF01213.19 EAQ89303.1 - 0.08 12.4 7.3 0.1 12.1 7.3 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal TFIIA PF03153.13 EAQ89303.1 - 0.28 11.2 4.7 0.28 11.1 4.7 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FTZ PF03867.14 EAQ89303.1 - 1.6 8.2 5.9 2.1 7.8 5.9 1.1 1 0 0 1 1 1 0 Fushi tarazu (FTZ), N-terminal region PRIMA1 PF16101.5 EAQ89303.1 - 3.9 7.5 14.2 2.6 8.1 10.9 2.0 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 PBP1_TM PF14812.6 EAQ89304.1 - 0.0041 17.5 3.3 0.0041 17.5 3.3 3.2 3 0 0 3 3 3 1 Transmembrane domain of transglycosylase PBP1 at N-terminal YL1 PF05764.13 EAQ89304.1 - 1.4 8.9 16.3 0.028 14.6 3.5 2.3 2 1 0 2 2 2 0 YL1 nuclear protein Polysacc_deac_1 PF01522.21 EAQ89305.1 - 1.5e-19 70.2 0.0 1.9e-19 69.8 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase Ank_4 PF13637.6 EAQ89306.1 - 0.086 13.5 0.1 0.41 11.3 0.0 2.2 1 1 1 2 2 2 0 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAQ89306.1 - 0.17 12.2 0.1 0.47 10.8 0.1 1.8 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Cys_Met_Meta_PP PF01053.20 EAQ89307.1 - 1.1e-55 188.7 0.0 2.5e-55 187.6 0.0 1.5 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Ofd1_CTDD PF10637.9 EAQ89309.1 - 4.2e-102 340.9 0.0 2.3e-97 325.4 0.2 2.2 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 EAQ89309.1 - 1.7e-25 89.5 0.0 1.2e-24 86.8 0.0 2.4 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 EAQ89309.1 - 7.6e-12 46.0 0.0 1.9e-11 44.7 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF1963 PF09234.10 EAQ89309.1 - 0.48 10.9 3.2 0.61 10.5 2.1 1.8 2 1 0 2 2 2 0 Domain of unknown function (DUF1963) Aminotran_5 PF00266.19 EAQ89310.1 - 4.3e-45 154.3 0.0 1.2e-44 152.8 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 EAQ89310.1 - 3e-05 22.7 0.0 4.3e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Galanin PF01296.18 EAQ89310.1 - 0.022 14.7 0.1 0.066 13.2 0.1 1.8 1 0 0 1 1 1 0 Galanin Ribul_P_3_epim PF00834.19 EAQ89311.1 - 4.9e-63 212.1 0.0 3e-31 108.3 0.0 2.1 1 1 1 2 2 2 2 Ribulose-phosphate 3 epimerase family Questin_oxidase PF14027.6 EAQ89312.1 - 6.3e-96 321.9 0.4 7.7e-96 321.6 0.4 1.1 1 0 0 1 1 1 1 Questin oxidase-like DUF3885 PF13021.6 EAQ89312.1 - 0.47 10.6 2.7 0.47 10.6 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3885) COesterase PF00135.28 EAQ89313.1 - 4.7e-48 164.3 0.0 6.1e-48 163.9 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EAQ89313.1 - 0.00022 21.2 0.0 0.00052 19.9 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold zf-C2H2 PF00096.26 EAQ89315.1 - 0.0026 18.1 3.7 0.34 11.5 0.4 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EAQ89315.1 - 0.024 15.5 2.0 8.8 7.5 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 EAQ89315.1 - 0.094 12.9 0.2 0.29 11.3 0.2 1.9 1 0 0 1 1 1 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 EAQ89315.1 - 0.16 12.4 1.1 0.37 11.3 0.0 2.2 2 0 0 2 2 2 0 Zinc-finger double domain Cullin PF00888.22 EAQ89316.1 - 5e-21 75.0 0.0 7.1e-21 74.5 0.0 1.1 1 0 0 1 1 1 1 Cullin family ANAPC2 PF08672.11 EAQ89316.1 - 5.1e-20 71.7 0.1 1.9e-19 69.9 0.1 2.1 1 0 0 1 1 1 1 Anaphase promoting complex (APC) subunit 2 zf-RING_2 PF13639.6 EAQ89317.1 - 1.5e-10 41.2 3.8 2.8e-10 40.4 3.8 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 EAQ89317.1 - 2.2e-09 37.5 2.8 6.1e-09 36.0 2.8 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 EAQ89317.1 - 7.7e-07 29.1 0.4 7.7e-07 29.1 0.4 1.7 2 0 0 2 2 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 EAQ89317.1 - 6.9e-06 25.8 5.0 2.1e-05 24.2 5.0 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EAQ89317.1 - 9.1e-05 22.3 2.3 0.00017 21.5 2.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EAQ89317.1 - 0.00012 21.8 1.6 0.00024 20.9 1.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EAQ89317.1 - 0.0002 21.1 2.4 0.00036 20.4 2.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EAQ89317.1 - 0.0011 18.9 3.9 0.0027 17.7 3.9 1.7 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 EAQ89317.1 - 0.0024 17.7 3.0 0.0049 16.7 3.0 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 EAQ89317.1 - 0.0037 16.8 1.6 0.009 15.6 1.6 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 EAQ89317.1 - 0.0065 16.6 3.9 0.1 12.8 3.9 2.3 1 1 0 1 1 1 1 FANCL C-terminal domain zf-RING_11 PF17123.5 EAQ89317.1 - 0.024 14.4 0.8 0.062 13.1 0.8 1.8 1 0 0 1 1 1 0 RING-like zinc finger zf-C3HC4_4 PF15227.6 EAQ89317.1 - 0.22 11.7 0.8 0.53 10.5 0.8 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING eIF-3_zeta PF05091.12 EAQ89317.1 - 3.3 6.6 7.7 5.8 5.8 7.7 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) APH PF01636.23 EAQ89318.1 - 4.3e-46 157.8 0.1 4.3e-46 157.8 0.1 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.20 EAQ89318.1 - 0.00035 20.0 0.0 0.00051 19.4 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase RIO1 PF01163.22 EAQ89318.1 - 0.0083 15.7 0.0 0.35 10.4 0.0 2.2 2 0 0 2 2 2 1 RIO1 family Choline_kinase PF01633.20 EAQ89318.1 - 0.014 15.0 0.0 0.024 14.2 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Fructosamin_kin PF03881.14 EAQ89318.1 - 0.019 14.2 0.0 0.077 12.2 0.0 1.9 1 1 0 1 1 1 0 Fructosamine kinase Kdo PF06293.14 EAQ89318.1 - 0.027 13.8 0.0 0.18 11.1 0.0 2.2 3 0 0 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family ORC5_C PF14630.6 EAQ89318.1 - 0.084 12.4 0.3 0.14 11.7 0.3 1.2 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 5 C-terminus DUF1679 PF07914.11 EAQ89318.1 - 0.15 10.9 0.0 1.5 7.6 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1679) Rad17 PF03215.15 EAQ89319.1 - 6.5e-24 84.9 0.0 5.5e-19 68.8 0.0 2.3 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_16 PF13191.6 EAQ89319.1 - 0.0012 19.2 0.0 0.0033 17.8 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 EAQ89319.1 - 0.0058 16.4 0.0 0.016 14.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 EAQ89319.1 - 0.018 15.0 0.0 0.036 14.0 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_22 PF13401.6 EAQ89319.1 - 0.028 14.7 0.0 0.071 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 EAQ89319.1 - 0.038 13.7 0.0 0.068 12.9 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase T2SSE PF00437.20 EAQ89319.1 - 0.05 12.7 0.0 0.093 11.8 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein TsaE PF02367.17 EAQ89319.1 - 0.063 13.3 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE CDC45 PF02724.14 EAQ89320.1 - 0.043 12.1 2.2 0.057 11.7 2.2 1.3 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 EAQ89320.1 - 6.4 6.1 18.8 9.3 5.6 18.8 1.2 1 0 0 1 1 1 0 SDA1 Pkr1 PF08636.10 EAQ89322.1 - 9e-33 112.2 3.0 1.2e-32 111.9 3.0 1.1 1 0 0 1 1 1 1 ER protein Pkr1 OAD_gamma PF04277.13 EAQ89322.1 - 1.1 9.9 4.1 0.66 10.6 0.1 2.3 1 1 1 2 2 2 0 Oxaloacetate decarboxylase, gamma chain LSM PF01423.22 EAQ89323.1 - 1.4e-17 63.2 0.0 1.7e-17 62.8 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EAQ89323.1 - 0.0016 18.5 0.0 0.0021 18.2 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain SelK_SelG PF10961.8 EAQ89323.1 - 0.0037 17.8 5.2 0.0055 17.3 5.2 1.2 1 0 0 1 1 1 1 Selenoprotein SelK_SelG FXMRP1_C_core PF12235.8 EAQ89323.1 - 8.6 7.0 10.4 5.6 7.6 8.7 1.6 2 0 0 2 2 2 0 Fragile X-related 1 protein core C terminal MccV PF17508.2 EAQ89324.1 - 1.2 9.7 6.2 0.56 10.8 0.4 2.6 2 1 0 2 2 2 0 Microcin V bacteriocin PKD_channel PF08016.12 EAQ89325.1 - 0.019 13.7 7.5 0.41 9.3 2.0 2.2 2 0 0 2 2 2 0 Polycystin cation channel Mt_ATP-synt_B PF05405.14 EAQ89326.1 - 9.6e-56 187.9 9.7 1.2e-55 187.6 9.7 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF3453 PF11935.8 EAQ89326.1 - 0.0027 17.4 2.4 0.67 9.5 0.4 2.5 2 1 0 2 2 2 2 Domain of unknown function (DUF3453) DUF1539 PF07560.11 EAQ89326.1 - 0.028 14.5 0.5 0.054 13.6 0.5 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1539) DUF932 PF06067.11 EAQ89326.1 - 0.081 12.7 3.2 0.14 11.9 3.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF932) GAS PF13851.6 EAQ89326.1 - 2.6 7.4 13.5 1.5 8.1 8.7 2.0 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding CBF PF03914.17 EAQ89327.1 - 7.2e-34 117.3 0.3 3.1e-33 115.2 0.1 2.2 2 0 0 2 2 2 1 CBF/Mak21 family Rep_fac_C PF08542.11 EAQ89327.1 - 0.044 14.2 0.1 0.69 10.4 0.0 2.5 2 0 0 2 2 2 0 Replication factor C C-terminal domain TMF_TATA_bd PF12325.8 EAQ89327.1 - 0.056 13.7 1.0 1.4 9.2 0.3 2.6 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF3201 PF11447.8 EAQ89327.1 - 0.14 11.7 3.2 14 5.2 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3201) SAT PF16073.5 EAQ89327.1 - 1.6 8.4 4.6 0.86 9.3 0.2 2.7 4 0 0 4 4 4 0 Starter unit:ACP transacylase in aflatoxin biosynthesis Tho2 PF11262.8 EAQ89327.1 - 2.5 7.2 6.0 0.35 10.0 0.8 2.1 3 0 0 3 3 3 0 Transcription factor/nuclear export subunit protein 2 Collagen PF01391.18 EAQ89328.1 - 0.0074 16.0 1.1 0.0074 16.0 1.1 1.9 2 0 0 2 2 2 1 Collagen triple helix repeat (20 copies) bZIP_1 PF00170.21 EAQ89329.1 - 1.3e-09 38.0 9.0 1.3e-09 38.0 9.0 2.7 2 1 1 3 3 3 1 bZIP transcription factor bZIP_2 PF07716.15 EAQ89329.1 - 2e-07 31.0 5.5 2e-07 31.0 5.5 2.9 2 1 1 3 3 3 1 Basic region leucine zipper bZIP_Maf PF03131.17 EAQ89329.1 - 5.1e-06 26.9 10.6 5.1e-06 26.9 10.6 2.2 2 1 0 2 2 2 1 bZIP Maf transcription factor Med6 PF04934.14 EAQ89329.1 - 0.0085 15.9 0.2 0.02 14.7 0.2 1.6 1 0 0 1 1 1 1 MED6 mediator sub complex component DUF3287 PF11690.8 EAQ89329.1 - 0.019 14.7 1.4 0.043 13.6 0.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3287) PI_PP_I PF18363.1 EAQ89329.1 - 0.032 14.4 0.7 0.074 13.2 0.7 1.6 1 0 0 1 1 1 0 Phosphoinositide phosphatase insertion domain LicD PF04991.13 EAQ89329.1 - 0.42 10.7 4.5 0.72 9.9 4.5 1.3 1 0 0 1 1 1 0 LicD family Exonuc_VII_L PF02601.15 EAQ89329.1 - 0.82 9.2 8.8 0.1 12.1 3.9 1.8 2 0 0 2 2 2 0 Exonuclease VII, large subunit UPF0242 PF06785.11 EAQ89329.1 - 1.5 8.9 15.3 3.2 7.8 15.3 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Jnk-SapK_ap_N PF09744.9 EAQ89329.1 - 1.8 8.7 21.7 0.091 13.0 15.5 1.9 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 FapA PF03961.13 EAQ89329.1 - 4.4 5.8 10.1 7.4 5.1 10.1 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A DivIC PF04977.15 EAQ89329.1 - 4.6 7.1 12.9 2.5 7.9 0.5 2.7 2 0 0 2 2 2 0 Septum formation initiator DUF1664 PF07889.12 EAQ89329.1 - 6.1 6.9 13.7 5.3 7.1 10.1 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Sel1 PF08238.12 EAQ89332.1 - 6.4e-08 33.0 0.1 0.64 10.8 0.0 4.7 5 0 0 5 5 5 3 Sel1 repeat WD40 PF00400.32 EAQ89334.1 - 5.2e-40 134.7 17.8 6.5e-06 26.8 0.3 9.8 10 1 0 10 10 10 8 WD domain, G-beta repeat Utp12 PF04003.12 EAQ89334.1 - 5.5e-19 68.4 0.1 1.6e-18 67.0 0.3 1.6 2 0 0 2 2 2 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 EAQ89334.1 - 3.2e-14 53.0 11.2 0.0025 18.1 0.1 7.3 5 2 4 9 9 9 5 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 EAQ89334.1 - 0.00032 19.6 2.3 0.068 11.9 0.2 3.4 2 1 0 4 4 4 2 Nup133 N terminal like WD40_like PF17005.5 EAQ89334.1 - 0.00051 19.5 0.2 1.5 8.0 0.0 3.7 3 1 1 4 4 4 2 WD40-like domain Ge1_WD40 PF16529.5 EAQ89334.1 - 0.0024 16.9 1.5 0.69 8.8 0.0 3.8 3 2 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 EAQ89334.1 - 0.018 13.4 0.0 0.23 9.7 0.0 2.3 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz RAB3GAP2_N PF14655.6 EAQ89334.1 - 0.13 11.5 1.3 3.6 6.8 0.0 3.5 3 1 0 4 4 4 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF3464 PF11947.8 EAQ89334.1 - 6.9 6.4 5.9 0.65 9.7 1.2 1.6 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 P34-Arc PF04045.14 EAQ89335.1 - 8.1e-79 264.7 0.7 5.4e-70 235.8 0.0 2.1 1 1 1 2 2 2 2 Arp2/3 complex, 34 kD subunit p34-Arc NAD_binding_8 PF13450.6 EAQ89336.1 - 8.8e-06 25.9 0.1 3.8e-05 23.8 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EAQ89336.1 - 0.0036 16.6 0.2 0.044 13.0 0.3 2.4 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EAQ89336.1 - 0.0062 15.3 0.0 0.01 14.6 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_9 PF13454.6 EAQ89336.1 - 0.0075 16.3 1.2 0.032 14.2 0.1 2.6 2 1 0 2 2 2 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 EAQ89336.1 - 0.0085 15.3 1.0 0.61 9.2 0.1 3.2 3 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 EAQ89336.1 - 0.0093 15.6 0.1 0.67 9.5 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EAQ89336.1 - 0.03 13.4 0.1 0.046 12.8 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 EAQ89336.1 - 0.034 13.4 0.0 0.071 12.3 0.0 1.5 1 0 0 1 1 1 0 Thi4 family 2-Hacid_dh_C PF02826.19 EAQ89336.1 - 0.042 13.2 0.0 0.08 12.3 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FMO-like PF00743.19 EAQ89336.1 - 0.043 12.2 0.6 3.5 5.9 0.0 2.7 1 1 2 3 3 3 0 Flavin-binding monooxygenase-like GIDA PF01134.22 EAQ89336.1 - 0.19 10.7 0.1 0.36 9.9 0.1 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A zf-CCCH PF00642.24 EAQ89337.1 - 1.1 9.2 7.6 14 5.7 0.0 3.2 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EAQ89337.1 - 2.9 8.1 7.1 1.6 8.9 1.0 2.9 3 0 0 3 3 3 0 Zinc finger domain TFIIF_beta PF02270.15 EAQ89338.1 - 1.6e-28 98.6 0.1 2.8e-28 97.8 0.1 1.4 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain Tau95 PF09734.9 EAQ89338.1 - 0.002 18.9 0.9 0.0033 18.2 0.9 1.5 1 1 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain HAD PF12710.7 EAQ89339.1 - 3e-07 31.0 2.7 0.00096 19.6 0.0 2.9 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EAQ89339.1 - 0.00082 19.7 1.0 0.31 11.3 0.2 2.5 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 EAQ89339.1 - 0.0056 16.1 0.0 0.99 8.8 0.0 2.2 2 0 0 2 2 2 2 Putative Phosphatase Hydrolase_3 PF08282.12 EAQ89339.1 - 0.031 14.0 1.4 0.037 13.8 0.1 1.7 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EAQ89339.1 - 0.14 12.2 0.0 2.8 8.0 0.0 2.2 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase S6PP PF05116.13 EAQ89339.1 - 0.28 10.7 0.3 0.95 8.9 0.0 1.8 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase SNase PF00565.17 EAQ89340.1 - 6.1e-20 71.7 0.0 1.2e-19 70.8 0.0 1.5 1 0 0 1 1 1 1 Staphylococcal nuclease homologue Kelch_6 PF13964.6 EAQ89341.1 - 0.0027 17.9 0.7 0.53 10.7 0.0 3.6 4 0 0 4 4 4 1 Kelch motif Reg_prop PF07494.11 EAQ89341.1 - 0.0059 16.7 0.0 2.2 8.8 0.0 3.2 2 0 0 2 2 2 1 Two component regulator propeller DUF1668 PF07893.13 EAQ89341.1 - 0.15 11.4 0.1 0.96 8.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1668) DUF5122 PF17164.4 EAQ89341.1 - 1.2 9.5 9.9 9.2 6.7 0.1 4.7 5 0 0 5 5 5 0 Domain of unknown function (DUF5122) beta-propeller zf-C2H2 PF00096.26 EAQ89345.1 - 1e-09 38.3 9.9 2.5e-05 24.5 4.5 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EAQ89345.1 - 1.8e-08 34.4 12.1 0.00045 20.5 0.2 3.4 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 EAQ89345.1 - 4.7e-07 30.1 9.4 0.0015 19.2 3.2 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 EAQ89345.1 - 5.9e-06 26.5 1.3 2.1e-05 24.8 1.3 2.0 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 EAQ89345.1 - 1.2e-05 25.1 8.3 0.00014 21.8 2.4 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EAQ89345.1 - 0.00077 19.7 3.5 0.00085 19.5 1.8 2.0 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 EAQ89345.1 - 0.045 14.1 1.0 0.066 13.5 0.3 1.6 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.6 EAQ89345.1 - 0.15 12.0 3.7 5.2 7.1 0.3 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_11 PF16622.5 EAQ89345.1 - 1.3 8.8 10.7 4.1 7.3 0.4 3.4 3 0 0 3 3 3 0 zinc-finger C2H2-type SF3b1 PF08920.10 EAQ89346.1 - 4.7e-26 91.6 11.7 7.8e-26 90.9 7.5 3.0 1 1 1 2 2 2 1 Splicing factor 3B subunit 1 HEAT_EZ PF13513.6 EAQ89346.1 - 1.2e-11 44.8 2.4 0.11 13.1 0.0 7.2 7 0 0 7 7 7 3 HEAT-like repeat HEAT_2 PF13646.6 EAQ89346.1 - 5.6e-09 36.3 15.4 0.1 13.0 0.1 8.3 6 3 3 10 10 10 4 HEAT repeats HEAT PF02985.22 EAQ89346.1 - 1.2e-08 34.5 7.4 0.75 10.2 0.0 8.8 8 0 0 8 8 8 1 HEAT repeat Vac14_Fab1_bd PF12755.7 EAQ89346.1 - 1.1e-05 26.0 0.4 1.1 9.9 0.0 5.3 6 0 0 6 6 6 1 Vacuolar 14 Fab1-binding region NUC173 PF08161.12 EAQ89346.1 - 0.00013 21.7 0.6 0.96 9.1 0.0 4.4 4 1 0 5 5 5 2 NUC173 domain DUF3385 PF11865.8 EAQ89346.1 - 0.00016 21.6 1.4 0.024 14.5 0.0 4.6 5 1 0 5 5 5 1 Domain of unknown function (DUF3385) Adaptin_N PF01602.20 EAQ89346.1 - 0.00074 18.2 0.2 0.13 10.8 0.1 3.0 2 2 1 3 3 3 1 Adaptin N terminal region CLASP_N PF12348.8 EAQ89346.1 - 0.012 15.2 0.2 1.8 8.0 0.0 3.5 4 1 0 4 4 4 0 CLASP N terminal DRIM PF07539.12 EAQ89346.1 - 0.02 13.2 0.5 3.6 5.8 0.1 3.7 2 1 2 4 4 4 0 Down-regulated in metastasis UNC45-central PF11701.8 EAQ89346.1 - 0.021 14.8 0.0 0.065 13.2 0.0 1.8 1 0 0 1 1 1 0 Myosin-binding striated muscle assembly central HECT_2 PF09814.9 EAQ89347.1 - 1.2e-41 142.9 0.6 1.2e-41 142.8 0.6 1.1 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding OGG_N PF07934.12 EAQ89348.1 - 5.4e-21 74.9 0.0 1.4e-20 73.6 0.0 1.7 2 0 0 2 2 2 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 EAQ89348.1 - 6.4e-14 52.3 0.0 1.1e-13 51.6 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 EAQ89348.1 - 0.019 14.8 0.0 0.049 13.5 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif RRM_1 PF00076.22 EAQ89349.1 - 4.8e-31 106.4 0.3 7.2e-13 48.2 0.0 3.6 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EAQ89349.1 - 0.00015 21.6 0.1 3 7.8 0.1 3.4 3 0 0 3 3 3 3 Occluded RNA-recognition motif DUF4411 PF14367.6 EAQ89349.1 - 0.049 13.5 0.0 0.089 12.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4411) Ribosomal_S13_N PF08069.12 EAQ89350.1 - 3.2e-30 104.0 0.1 5.5e-30 103.2 0.1 1.4 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 EAQ89350.1 - 6e-15 55.2 0.2 8.9e-15 54.7 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.18 EAQ89350.1 - 0.044 13.7 0.0 0.11 12.4 0.0 1.7 2 0 0 2 2 2 0 'Paired box' domain Dpy-30 PF05186.13 EAQ89351.1 - 1.1e-05 25.1 0.0 1.6e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Dpy-30 motif DUF1387 PF07139.11 EAQ89351.1 - 1.1 9.0 3.2 1.2 8.8 3.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) CDC27 PF09507.10 EAQ89351.1 - 5.1 6.4 10.5 6 6.1 10.5 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 TFIIA PF03153.13 EAQ89351.1 - 7.4 6.5 12.4 8 6.3 12.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit VRR_NUC PF08774.11 EAQ89352.1 - 4.4e-22 78.2 0.0 1.1e-21 76.9 0.0 1.7 1 0 0 1 1 1 1 VRR-NUC domain CBFB_NFYA PF02045.15 EAQ89355.1 - 4.8e-28 97.5 4.6 9.9e-28 96.5 4.6 1.6 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Hus1 PF04005.12 EAQ89355.1 - 0.25 10.4 0.0 0.37 9.9 0.0 1.2 1 0 0 1 1 1 0 Hus1-like protein LSM PF01423.22 EAQ89356.1 - 8.8e-18 63.8 0.7 1.1e-17 63.5 0.7 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EAQ89356.1 - 0.0022 18.1 0.0 0.0027 17.8 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain Hfq PF17209.3 EAQ89356.1 - 0.0066 16.1 0.0 0.0094 15.6 0.0 1.3 1 0 0 1 1 1 1 Hfq protein DUF1461 PF07314.11 EAQ89356.1 - 0.12 12.3 0.1 0.12 12.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1461) DRMBL PF07522.14 EAQ89357.1 - 1.7e-13 50.7 0.0 2.4e-11 43.8 0.0 2.3 2 0 0 2 2 2 2 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 EAQ89357.1 - 5.4e-06 26.0 0.0 9.3e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain eIF-3_zeta PF05091.12 EAQ89358.1 - 1.4e-208 694.1 0.0 1.7e-208 693.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF569 PF04601.13 EAQ89358.1 - 0.0017 18.1 0.0 0.0038 16.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF569) Pkinase PF00069.25 EAQ89362.1 - 8.2e-63 212.2 0.0 3.3e-39 134.8 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ89362.1 - 2.1e-26 92.8 0.0 3.7e-20 72.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.24 EAQ89362.1 - 1.2e-12 47.9 0.0 2.7e-12 46.8 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.6 EAQ89362.1 - 7.8e-08 32.0 0.0 4e-05 23.1 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 EAQ89362.1 - 6.5e-05 23.0 0.0 0.0052 16.7 0.2 2.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family PAS_9 PF13426.7 EAQ89362.1 - 0.0003 21.0 0.0 0.00068 19.9 0.0 1.5 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 EAQ89362.1 - 0.0022 17.9 0.1 0.04 13.9 0.0 2.4 2 0 0 2 2 2 1 PAS fold Haspin_kinase PF12330.8 EAQ89362.1 - 0.0081 15.1 0.0 0.015 14.3 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EAQ89362.1 - 0.011 15.1 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PAS_4 PF08448.10 EAQ89362.1 - 0.11 12.7 0.0 0.31 11.3 0.0 1.7 1 0 0 1 1 1 0 PAS fold Seadorna_VP7 PF07387.11 EAQ89362.1 - 0.13 11.3 0.1 0.22 10.6 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Serglycin PF04360.12 EAQ89362.1 - 0.43 10.5 4.4 1.3 9.0 4.4 1.8 1 0 0 1 1 1 0 Serglycin Sugar_tr PF00083.24 EAQ89363.1 - 1.2e-25 90.3 22.9 7.4e-23 81.1 22.9 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter HTH_psq PF05225.16 EAQ89364.1 - 1.9e-05 24.3 0.1 3.8e-05 23.3 0.1 1.5 1 0 0 1 1 1 1 helix-turn-helix, Psq domain BrkDBD PF09607.10 EAQ89364.1 - 0.14 12.0 0.1 0.29 11.0 0.1 1.6 1 0 0 1 1 1 0 Brinker DNA-binding domain DUF3692 PF12469.8 EAQ89365.1 - 0.18 12.1 0.0 0.4 10.9 0.0 1.6 1 0 0 1 1 1 0 CRISPR-associated protein Zn_clus PF00172.18 EAQ89365.1 - 0.25 11.5 1.1 0.42 10.8 1.1 1.2 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Epimerase PF01370.21 EAQ89370.1 - 8.6e-26 90.9 0.0 1.1e-25 90.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EAQ89370.1 - 8.3e-16 58.3 1.6 2.3e-14 53.6 1.6 2.0 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EAQ89370.1 - 1.2e-08 34.5 2.9 1.1e-06 28.0 0.3 3.1 2 1 1 3 3 3 2 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 EAQ89370.1 - 1.7e-08 33.9 0.0 0.00027 20.1 0.0 2.1 2 0 0 2 2 2 2 RmlD substrate binding domain NAD_binding_4 PF07993.12 EAQ89370.1 - 2.3e-06 27.0 0.3 9.5e-06 25.0 0.0 1.9 2 0 0 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.19 EAQ89370.1 - 0.00092 18.3 0.0 0.23 10.5 0.1 2.7 2 1 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Gln-synt_C PF00120.24 EAQ89371.1 - 2.2e-12 46.6 0.0 2.8e-11 43.0 0.0 2.0 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 EAQ89371.1 - 4e-12 45.7 0.0 7e-12 44.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Protoglobin PF11563.8 EAQ89373.1 - 1.5e-59 200.4 0.2 1.7e-59 200.2 0.2 1.1 1 0 0 1 1 1 1 Protoglobin Lactamase_B_3 PF13483.6 EAQ89374.1 - 3.5e-14 53.0 0.0 4.5e-14 52.7 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 EAQ89374.1 - 3.5e-13 49.5 0.0 5.1e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain AAA PF00004.29 EAQ89376.1 - 6.8e-43 146.3 0.0 1.2e-42 145.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EAQ89376.1 - 7.8e-11 41.6 0.1 1.4e-10 40.8 0.1 1.4 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 EAQ89376.1 - 1e-10 41.4 0.0 5e-10 39.2 0.0 2.1 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_16 PF13191.6 EAQ89376.1 - 1.1e-07 32.4 0.0 6.7e-05 23.3 0.1 2.9 2 1 1 3 3 3 1 AAA ATPase domain AAA_2 PF07724.14 EAQ89376.1 - 1.9e-06 28.1 0.0 9.2e-06 25.9 0.0 2.2 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 EAQ89376.1 - 1.9e-06 27.9 0.1 3.8e-05 23.7 0.1 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EAQ89376.1 - 7.1e-06 25.8 0.0 1.5e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EAQ89376.1 - 0.00022 21.5 0.1 0.006 16.9 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.6 EAQ89376.1 - 0.00024 21.7 0.4 0.0025 18.3 0.0 2.6 3 1 0 3 3 3 1 AAA domain DUF815 PF05673.13 EAQ89376.1 - 0.00031 20.0 0.0 0.00076 18.7 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_7 PF12775.7 EAQ89376.1 - 0.0012 18.4 0.0 0.0023 17.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region TIP49 PF06068.13 EAQ89376.1 - 0.0023 17.2 0.0 0.0043 16.3 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain Mg_chelatase PF01078.21 EAQ89376.1 - 0.0037 16.7 0.0 0.0074 15.7 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 EAQ89376.1 - 0.0041 17.3 0.0 0.01 16.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 EAQ89376.1 - 0.0045 17.0 0.0 0.0097 15.9 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 EAQ89376.1 - 0.0059 16.4 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.6 EAQ89376.1 - 0.0059 16.6 0.0 0.016 15.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 EAQ89376.1 - 0.006 17.0 0.0 0.012 16.0 0.0 1.5 1 0 0 1 1 1 1 RNA helicase Sigma54_activat PF00158.26 EAQ89376.1 - 0.0083 15.8 0.0 0.027 14.2 0.0 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.11 EAQ89376.1 - 0.013 15.3 0.0 0.03 14.2 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 EAQ89376.1 - 0.018 14.8 0.0 0.057 13.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 EAQ89376.1 - 0.035 13.9 0.4 0.26 11.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 EAQ89376.1 - 0.04 13.2 0.3 0.13 11.5 0.0 2.0 3 0 0 3 3 3 0 KaiC Prot_ATP_OB_N PF17758.1 EAQ89376.1 - 0.042 13.5 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 Proteasomal ATPase OB N-terminal domain AAA_30 PF13604.6 EAQ89376.1 - 0.052 13.3 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EAQ89376.1 - 0.056 13.4 0.1 0.15 12.0 0.0 1.7 2 0 0 2 2 2 0 NACHT domain PhoH PF02562.16 EAQ89376.1 - 0.064 12.7 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 EAQ89376.1 - 0.087 12.4 0.0 0.22 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EAQ89376.1 - 0.09 13.0 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EAQ89376.1 - 0.1 11.9 0.1 0.26 10.5 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin eIF-1a PF01176.19 EAQ89376.1 - 0.11 12.3 0.1 0.2 11.5 0.1 1.4 1 0 0 1 1 1 0 Translation initiation factor 1A / IF-1 Parvo_NS1 PF01057.17 EAQ89376.1 - 0.12 11.4 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 SIS PF01380.22 EAQ89377.1 - 4.2e-60 201.3 0.2 6.8e-32 110.1 0.1 2.3 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 EAQ89377.1 - 1.7e-18 67.1 0.0 3.7e-18 66.0 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 EAQ89377.1 - 1.5e-10 41.1 0.0 3.6e-10 39.8 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 EAQ89377.1 - 0.0043 16.0 0.0 0.007 15.3 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.6 EAQ89377.1 - 0.063 13.3 0.0 1.5 8.9 0.0 2.5 2 1 0 2 2 2 0 SIS domain Dynactin_p22 PF07426.11 EAQ89377.1 - 0.32 10.9 2.8 0.31 10.9 0.3 2.2 2 0 0 2 2 2 0 Dynactin subunit p22 Proteasome PF00227.26 EAQ89378.1 - 3.3e-25 88.7 0.0 3.1e-24 85.5 0.0 2.0 1 1 0 1 1 1 1 Proteasome subunit HCNGP PF07818.13 EAQ89379.1 - 5e-14 52.7 0.0 1.2e-13 51.5 0.0 1.7 1 0 0 1 1 1 1 HCNGP-like protein PhzC-PhzF PF02567.16 EAQ89379.1 - 0.041 13.3 0.2 0.063 12.7 0.2 1.2 1 0 0 1 1 1 0 Phenazine biosynthesis-like protein DUF3712 PF12505.8 EAQ89380.1 - 2.3e-26 92.5 0.7 5.1e-26 91.4 0.7 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3712) SP_C-Propep PF08999.10 EAQ89380.1 - 0.021 14.6 0.7 0.04 13.7 0.7 1.5 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide Phage_holin_3_6 PF07332.11 EAQ89380.1 - 0.14 12.2 1.2 0.23 11.5 1.2 1.3 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III FMN_dh PF01070.18 EAQ89381.1 - 8.2e-104 347.4 0.1 9.9e-104 347.1 0.1 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 EAQ89381.1 - 5.9e-18 64.8 0.0 2.1e-17 63.0 0.0 1.8 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain IMPDH PF00478.25 EAQ89381.1 - 4.4e-06 25.9 0.0 0.00015 20.9 0.0 2.6 3 0 0 3 3 3 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 EAQ89381.1 - 1.1e-05 24.8 0.0 1.7e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.21 EAQ89381.1 - 0.017 14.6 0.0 0.031 13.7 0.0 1.3 1 0 0 1 1 1 0 Histidine biosynthesis protein ATP11 PF06644.11 EAQ89381.1 - 0.038 13.8 0.0 0.055 13.3 0.0 1.1 1 0 0 1 1 1 0 ATP11 protein NMO PF03060.15 EAQ89381.1 - 0.14 11.5 0.1 0.24 10.7 0.1 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase BPL_C PF02237.17 EAQ89381.1 - 0.17 11.8 0.0 0.44 10.5 0.0 1.6 1 0 0 1 1 1 0 Biotin protein ligase C terminal domain Ribul_P_3_epim PF00834.19 EAQ89381.1 - 0.19 11.1 0.0 0.29 10.5 0.0 1.2 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family Lipase_GDSL_2 PF13472.6 EAQ89382.1 - 1.6e-21 77.6 0.0 2e-21 77.2 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EAQ89382.1 - 1.1e-06 28.8 0.0 1.9e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase PCI PF01399.27 EAQ89383.1 - 6.4e-11 42.7 0.0 1.6e-10 41.4 0.0 1.6 1 0 0 1 1 1 1 PCI domain Egh16-like PF11327.8 EAQ89384.1 - 9.4e-45 153.3 0.0 1.8e-44 152.4 0.0 1.5 1 1 0 1 1 1 1 Egh16-like virulence factor DnaJ PF00226.31 EAQ89385.1 - 0.05 13.7 0.1 2.2 8.5 0.0 2.3 2 0 0 2 2 2 0 DnaJ domain Caskin1-CID PF16600.5 EAQ89386.1 - 8.4 7.1 11.6 3.8 8.2 0.4 3.1 2 0 0 2 2 2 0 Caskin1 CASK-interaction domain SNF2_N PF00176.23 EAQ89390.1 - 1.6e-34 119.2 0.0 3.6e-34 118.0 0.0 1.5 2 0 0 2 2 2 1 SNF2 family N-terminal domain ResIII PF04851.15 EAQ89390.1 - 0.064 13.3 0.0 5.9 6.9 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Asn_synthase PF00733.21 EAQ89391.1 - 4.8e-51 174.5 0.1 7.1e-51 173.9 0.1 1.1 1 0 0 1 1 1 1 Asparagine synthase GATase_6 PF13522.6 EAQ89391.1 - 9.9e-25 87.3 0.0 3.9e-24 85.4 0.0 2.0 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_7 PF13537.6 EAQ89391.1 - 2.8e-23 82.2 0.0 5.4e-23 81.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain Peptidase_S28 PF05577.12 EAQ89394.1 - 5.2e-47 160.6 0.0 3.8e-46 157.8 0.0 1.9 1 1 0 1 1 1 1 Serine carboxypeptidase S28 NAD_binding_6 PF08030.12 EAQ89395.1 - 1.2e-15 58.0 0.0 2.1e-15 57.2 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 EAQ89395.1 - 9.8e-08 32.6 0.0 8e-07 29.7 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_8 PF08022.12 EAQ89395.1 - 0.011 15.8 0.0 0.037 14.1 0.0 2.0 1 1 0 1 1 1 0 FAD-binding domain SUI1 PF01253.22 EAQ89395.1 - 0.016 15.7 0.3 0.047 14.2 0.0 1.8 2 0 0 2 2 2 0 Translation initiation factor SUI1 Ctr PF04145.15 EAQ89396.1 - 1.2e-37 129.7 0.0 2.2e-37 128.9 0.0 1.4 1 0 0 1 1 1 1 Ctr copper transporter family Amidase PF01425.21 EAQ89397.1 - 3.4e-31 108.7 0.2 5.2e-31 108.1 0.2 1.2 1 0 0 1 1 1 1 Amidase F-box-like PF12937.7 EAQ89398.1 - 0.0087 15.9 0.4 0.026 14.4 0.0 2.0 2 1 0 2 2 2 1 F-box-like CENP-B_dimeris PF09026.10 EAQ89398.1 - 0.018 15.4 10.1 0.018 15.4 10.1 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain FAM176 PF14851.6 EAQ89398.1 - 0.058 13.1 1.5 0.35 10.5 0.4 2.1 2 0 0 2 2 2 0 FAM176 family CDC45 PF02724.14 EAQ89398.1 - 0.094 11.0 0.1 0.15 10.4 0.1 1.2 1 0 0 1 1 1 0 CDC45-like protein RXT2_N PF08595.11 EAQ89398.1 - 0.74 9.8 5.4 1.4 8.9 2.8 2.1 2 0 0 2 2 2 0 RXT2-like, N-terminal RTA1 PF04479.13 EAQ89399.1 - 3e-25 89.1 10.3 1.1e-16 61.0 2.9 2.2 1 1 1 2 2 2 2 RTA1 like protein OmdA PF13376.6 EAQ89399.1 - 0.19 11.8 0.1 0.36 10.9 0.1 1.4 1 0 0 1 1 1 0 Bacteriocin-protection, YdeI or OmpD-Associated DUF3995 PF13160.6 EAQ89399.1 - 0.57 10.5 14.9 0.12 12.8 1.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3995) Fungal_trans_2 PF11951.8 EAQ89400.1 - 5.3e-19 68.3 0.0 7.3e-19 67.8 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EAQ89400.1 - 3.3e-05 23.9 5.5 3.3e-05 23.9 5.5 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Toxin_12 PF07740.12 EAQ89402.1 - 0.0016 19.1 5.4 0.002 18.7 5.4 1.2 1 0 0 1 1 1 1 Ion channel inhibitory toxin Pkinase PF00069.25 EAQ89403.1 - 0.011 15.1 0.0 0.015 14.7 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain DUF2457 PF10446.9 EAQ89404.1 - 0.0075 15.5 4.3 0.015 14.5 4.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) RVT_2 PF07727.14 EAQ89405.1 - 3.5e-34 118.5 0.0 1.1e-33 116.9 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 EAQ89405.1 - 0.00042 19.9 0.0 0.001 18.7 0.0 1.7 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 EAQ89405.1 - 0.0071 17.0 0.2 0.03 15.0 0.2 2.1 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Glycos_transf_2 PF00535.26 EAQ89406.1 - 0.025 14.4 0.1 0.039 13.8 0.1 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 2 RisS_PPD PF16524.5 EAQ89406.1 - 0.051 13.8 0.3 1.1 9.6 0.1 2.1 1 1 1 2 2 2 0 Periplasmic domain of Sensor histidine kinase RisS adh_short PF00106.25 EAQ89407.1 - 8.9e-35 119.9 0.0 1.2e-34 119.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EAQ89407.1 - 2.8e-33 115.4 0.1 4.1e-33 114.9 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EAQ89407.1 - 8.1e-08 32.4 0.2 1.3e-07 31.8 0.2 1.3 1 0 0 1 1 1 1 KR domain RVT_1 PF00078.27 EAQ89408.1 - 1.2e-36 126.3 0.0 1.7e-36 125.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Helitron_like_N PF14214.6 EAQ89410.1 - 1e-23 84.5 3.9 4.1e-20 72.8 0.2 2.8 2 1 1 3 3 3 2 Helitron helicase-like domain at N-terminus PIF1 PF05970.14 EAQ89410.1 - 1.1e-16 61.0 0.3 1.5e-07 31.0 0.0 3.3 2 2 1 3 3 3 3 PIF1-like helicase UvrD_C_2 PF13538.6 EAQ89410.1 - 0.00039 20.2 0.0 0.00093 19.0 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.14 EAQ89410.1 - 0.0054 14.7 0.0 0.0079 14.2 0.0 1.1 1 0 0 1 1 1 1 Helicase AAA_30 PF13604.6 EAQ89410.1 - 0.0095 15.7 0.0 0.026 14.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain Nif11 PF07862.11 EAQ89410.1 - 0.036 14.4 0.1 0.092 13.1 0.1 1.7 1 0 0 1 1 1 0 Nif11 domain RVT_1 PF00078.27 EAQ89411.1 - 5e-31 108.0 0.0 5.9e-31 107.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ank_2 PF12796.7 EAQ89412.1 - 0.0085 16.7 0.0 0.024 15.2 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) PAP2_3 PF14378.6 EAQ89413.1 - 2.6e-37 128.4 9.2 2.5e-27 95.8 3.3 2.5 2 0 0 2 2 2 2 PAP2 superfamily PAP2 PF01569.21 EAQ89413.1 - 0.00028 20.7 1.3 0.00028 20.7 1.3 2.1 3 0 0 3 3 3 1 PAP2 superfamily PAP2_C PF14360.6 EAQ89413.1 - 0.016 15.8 1.6 0.035 14.6 0.1 2.4 2 0 0 2 2 2 0 PAP2 superfamily C-terminal SR-25 PF10500.9 EAQ89413.1 - 0.5 9.9 4.4 0.73 9.4 4.4 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF3328 PF11807.8 EAQ89415.1 - 2.5e-20 73.2 0.1 9.5e-20 71.3 0.0 1.8 1 1 1 2 2 2 1 Domain of unknown function (DUF3328) Methyltransf_2 PF00891.18 EAQ89416.1 - 4.1e-23 81.8 0.0 7.6e-23 80.9 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_25 PF13649.6 EAQ89416.1 - 9.7e-05 23.0 0.0 0.00032 21.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAQ89416.1 - 0.0025 17.6 0.0 0.0045 16.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Sigma70_r4 PF04545.16 EAQ89416.1 - 0.0057 16.2 0.0 0.011 15.3 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 CheR PF01739.18 EAQ89416.1 - 0.073 12.5 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Methyltransf_12 PF08242.12 EAQ89416.1 - 0.12 13.2 0.0 0.22 12.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain BatA PF07584.11 EAQ89417.1 - 0.07 13.5 2.8 0.85 10.0 0.3 2.4 2 0 0 2 2 2 0 Aerotolerance regulator N-terminal VIT PF08487.10 EAQ89418.1 - 3.9e-35 120.4 0.7 7.1e-35 119.6 0.1 1.8 2 0 0 2 2 2 1 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.6 EAQ89418.1 - 1.6e-23 83.4 0.0 2.9e-23 82.5 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT_2 PF13757.6 EAQ89418.1 - 2.7e-13 49.6 0.1 8.4e-13 48.0 0.1 1.8 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA PF00092.28 EAQ89418.1 - 5.3e-09 36.6 0.0 8.6e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 EAQ89418.1 - 4.1e-07 30.6 0.0 9.9e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 EAQ89418.1 - 0.013 14.9 0.0 0.025 14.0 0.0 1.4 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein Ribosomal_60s PF00428.19 EAQ89418.1 - 0.086 13.4 5.0 0.79 10.4 0.4 3.2 3 0 0 3 3 3 0 60s Acidic ribosomal protein ADH_zinc_N PF00107.26 EAQ89420.1 - 2.3e-07 30.9 0.2 6.4e-07 29.4 0.2 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EAQ89420.1 - 2.7e-06 27.2 0.0 6.2e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Colicin_V PF02674.16 EAQ89421.1 - 0.019 15.0 0.2 0.019 15.0 0.2 1.9 2 0 0 2 2 2 0 Colicin V production protein SPT_ssu-like PF11779.8 EAQ89421.1 - 0.14 11.8 0.0 0.4 10.3 0.0 1.7 1 0 0 1 1 1 0 Small subunit of serine palmitoyltransferase-like SUIM_assoc PF16619.5 EAQ89424.1 - 0.038 14.1 1.8 0.15 12.2 1.8 2.0 1 1 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Zn_clus PF00172.18 EAQ89425.1 - 1.3e-07 31.6 5.9 1.3e-07 31.6 5.9 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.25 EAQ89426.1 - 1e-37 129.5 2.2 1.3e-37 129.2 2.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EAQ89426.1 - 7.5e-29 100.9 4.3 1.9e-27 96.3 4.3 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EAQ89426.1 - 3.2e-08 33.7 0.9 5.4e-08 33.0 0.9 1.4 1 1 0 1 1 1 1 KR domain DUF3236 PF11576.8 EAQ89426.1 - 0.014 15.1 1.0 0.025 14.3 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3236) DFP PF04127.15 EAQ89426.1 - 1.4 8.7 6.6 9.4 6.0 6.6 1.9 1 1 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein DUF2726 PF10881.8 EAQ89427.1 - 0.069 13.0 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2726) Cytomega_UL20A PF05984.12 EAQ89427.1 - 0.4 11.0 3.8 1.5 9.1 3.8 2.0 1 0 0 1 1 1 0 Cytomegalovirus UL20A protein DUF1075 PF06388.11 EAQ89427.1 - 2.2 8.3 5.4 0.4 10.7 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1075) APH PF01636.23 EAQ89428.1 - 9.7e-06 25.7 5.5 3.1e-05 24.0 5.4 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EAQ89428.1 - 0.012 15.2 0.1 0.14 11.7 0.0 2.1 2 0 0 2 2 2 0 Choline/ethanolamine kinase Zn_clus PF00172.18 EAQ89431.1 - 0.012 15.7 15.1 0.015 15.4 10.6 2.7 2 1 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain NicO PF03824.16 EAQ89431.1 - 0.12 11.7 0.8 0.16 11.2 0.8 1.1 1 0 0 1 1 1 0 High-affinity nickel-transport protein SelP_N PF04592.14 EAQ89431.1 - 7.5 5.9 14.8 14 5.0 14.8 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Condensation PF00668.20 EAQ89433.1 - 1.2e-78 264.8 0.0 1.7e-78 264.4 0.0 1.1 1 0 0 1 1 1 1 Condensation domain adh_short_C2 PF13561.6 EAQ89433.1 - 1.9e-58 197.8 0.8 3.1e-58 197.1 0.8 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase AMP-binding PF00501.28 EAQ89433.1 - 8.8e-53 179.4 0.0 2e-37 128.8 0.0 2.5 1 1 1 2 2 2 2 AMP-binding enzyme adh_short PF00106.25 EAQ89433.1 - 4.7e-45 153.5 0.5 8.4e-45 152.6 0.5 1.4 1 0 0 1 1 1 1 short chain dehydrogenase PP-binding PF00550.25 EAQ89433.1 - 4.4e-11 43.0 0.0 1.6e-10 41.2 0.0 2.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site KR PF08659.10 EAQ89433.1 - 1.8e-09 37.7 1.7 3.4e-08 33.6 0.6 2.4 2 0 0 2 2 2 1 KR domain AMP-binding_C PF13193.6 EAQ89433.1 - 0.0013 19.7 0.0 0.0052 17.7 0.0 2.1 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Acetyltransf_6 PF13480.7 EAQ89433.1 - 0.049 13.8 0.7 0.45 10.7 0.2 2.9 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain F-box-like PF12937.7 EAQ89435.1 - 1.2e-08 34.7 0.1 2.6e-08 33.6 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EAQ89435.1 - 0.052 13.5 0.1 0.19 11.7 0.1 2.0 1 1 0 1 1 1 0 F-box domain Pox_T4_N PF04491.12 EAQ89436.1 - 0.15 11.9 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 Poxvirus T4 protein, N terminus F-box-like PF12937.7 EAQ89437.1 - 0.016 15.1 0.0 0.044 13.7 0.0 1.8 1 0 0 1 1 1 0 F-box-like Dimer_Tnp_hAT PF05699.14 EAQ89438.1 - 1.8e-16 59.7 0.3 2.7e-16 59.1 0.3 1.2 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Exo_endo_phos_2 PF14529.6 EAQ89439.1 - 7.3e-12 45.2 0.0 1.9e-11 43.9 0.0 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 EAQ89439.1 - 1.8e-07 30.9 0.2 9.1e-07 28.6 0.2 2.2 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Glyco_hydro_61 PF03443.14 EAQ89440.1 - 3e-46 158.0 0.1 4.5e-46 157.4 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.18 EAQ89440.1 - 1.9e-11 43.7 13.4 1.9e-11 43.7 13.4 2.5 2 0 0 2 2 2 1 Fungal cellulose binding domain Helicase_C PF00271.31 EAQ89442.1 - 1.6e-08 34.9 0.0 3.6e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EAQ89442.1 - 8e-06 26.0 0.0 1.6e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAQ89442.1 - 2.7e-05 24.0 0.0 5.1e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-C2H2_jaz PF12171.8 EAQ89443.1 - 0.02 15.2 12.1 0.43 10.9 0.0 4.0 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 EAQ89443.1 - 0.046 14.6 0.9 0.046 14.6 0.9 4.8 4 0 0 4 4 4 0 C2H2-type zinc finger zf-met PF12874.7 EAQ89443.1 - 0.056 13.9 3.3 1.5 9.3 0.0 3.1 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 EAQ89443.1 - 0.2 12.1 9.2 0.03 14.8 4.5 2.2 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2 PF00096.26 EAQ89443.1 - 0.71 10.4 17.1 0.16 12.5 0.9 4.4 4 0 0 4 4 4 0 Zinc finger, C2H2 type Zn_clus PF00172.18 EAQ89443.1 - 0.81 9.9 17.9 0.086 13.0 10.2 2.5 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain F-box-like PF12937.7 EAQ89444.1 - 0.05 13.5 0.3 0.18 11.7 0.3 2.0 1 1 0 1 1 1 0 F-box-like zf-RVT PF13966.6 EAQ89445.1 - 0.0094 16.7 0.0 0.038 14.7 0.0 2.0 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase Glyco_hydro_2_N PF02837.18 EAQ89447.1 - 2.3e-13 50.4 0.0 5.4e-13 49.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.21 EAQ89447.1 - 4.1e-10 40.3 0.0 8.9e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_C PF02836.17 EAQ89447.1 - 0.00061 19.0 0.2 0.0022 17.2 0.1 1.9 2 1 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain FAD_binding_3 PF01494.19 EAQ89448.1 - 3.3e-31 108.8 0.0 8.2e-31 107.5 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 EAQ89448.1 - 0.00014 21.2 0.0 0.0075 15.6 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 EAQ89448.1 - 0.00032 20.1 0.0 0.067 12.5 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EAQ89448.1 - 0.00041 20.5 0.1 0.001 19.2 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EAQ89448.1 - 0.001 18.4 0.2 1.2 8.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EAQ89448.1 - 0.01 16.4 0.2 1.7 9.2 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EAQ89448.1 - 0.019 14.6 0.1 0.091 12.3 0.0 2.0 2 1 0 2 2 2 0 FAD dependent oxidoreductase ApbA PF02558.16 EAQ89448.1 - 0.059 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_binding_2 PF00890.24 EAQ89448.1 - 0.06 12.4 0.0 0.19 10.8 0.0 1.8 2 0 0 2 2 2 0 FAD binding domain Pilin_N PF07790.11 EAQ89450.1 - 0.11 13.4 0.3 0.26 12.2 0.3 1.5 1 0 0 1 1 1 0 Archaeal Type IV pilin, N-terminal DUF1515 PF07439.11 EAQ89450.1 - 0.14 12.2 1.1 0.36 10.9 1.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) DNA_ligase_IV PF11411.8 EAQ89450.1 - 1.7 8.9 3.5 1.3 9.2 0.2 2.5 3 0 0 3 3 3 0 DNA ligase IV Amidoligase_2 PF12224.8 EAQ89452.1 - 1e-10 41.7 0.0 4.2e-07 29.9 0.0 2.2 1 1 0 2 2 2 2 Putative amidoligase enzyme PARM PF17061.5 EAQ89453.1 - 3.6 7.7 12.5 4.9 7.2 12.5 1.4 1 0 0 1 1 1 0 PARM CBM_1 PF00734.18 EAQ89456.1 - 3.5e-12 46.0 16.4 1.4e-11 44.1 16.4 2.2 1 0 0 1 1 1 1 Fungal cellulose binding domain Peptidase_S9 PF00326.21 EAQ89456.1 - 6.6e-06 25.7 0.0 4.1e-05 23.1 0.1 1.9 2 0 0 2 2 2 1 Prolyl oligopeptidase family Esterase_phd PF10503.9 EAQ89456.1 - 0.00035 20.2 0.2 0.0022 17.6 0.1 2.0 1 1 1 2 2 2 1 Esterase PHB depolymerase Esterase PF00756.20 EAQ89456.1 - 0.012 15.2 0.5 0.041 13.5 0.5 1.8 1 1 0 1 1 1 0 Putative esterase Abhydrolase_2 PF02230.16 EAQ89456.1 - 0.021 14.6 0.0 0.034 14.0 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase DUF1275 PF06912.11 EAQ89457.1 - 3.9e-47 160.7 13.1 4.6e-47 160.4 13.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) PIG-P PF08510.12 EAQ89457.1 - 1 9.3 3.5 19 5.2 0.6 2.7 2 0 0 2 2 2 0 PIG-P Cupin_1 PF00190.22 EAQ89458.1 - 1.7e-40 138.1 0.0 1.8e-20 73.1 0.0 2.1 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 EAQ89458.1 - 2.5e-26 91.2 1.2 1.5e-13 50.2 0.2 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 EAQ89458.1 - 3.1e-09 36.4 0.1 0.001 18.7 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.19 EAQ89458.1 - 2.2e-08 34.1 0.2 0.00079 19.3 0.0 2.3 2 0 0 2 2 2 2 AraC-like ligand binding domain MannoseP_isomer PF01050.18 EAQ89458.1 - 0.00019 21.4 0.0 0.06 13.2 0.0 2.2 2 0 0 2 2 2 2 Mannose-6-phosphate isomerase ARD PF03079.14 EAQ89458.1 - 0.0063 16.7 0.6 3.8 7.7 0.1 2.2 2 0 0 2 2 2 2 ARD/ARD' family 3-HAO PF06052.12 EAQ89458.1 - 0.012 15.2 0.0 0.67 9.6 0.0 2.3 2 0 0 2 2 2 0 3-hydroxyanthranilic acid dioxygenase Cupin_7 PF12973.7 EAQ89458.1 - 0.015 15.2 0.3 0.84 9.6 0.0 3.1 2 1 1 3 3 3 0 ChrR Cupin-like domain AAA PF00004.29 EAQ89459.1 - 3.3e-07 30.8 1.0 0.016 15.6 0.1 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EAQ89459.1 - 0.0075 16.7 0.0 0.017 15.5 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain HET-s_218-289 PF11558.8 EAQ89459.1 - 0.11 12.6 0.0 0.34 11.0 0.0 1.8 2 0 0 2 2 2 0 Het-s 218-289 SpoIIIAH PF12685.7 EAQ89459.1 - 0.67 9.7 13.7 9.8 5.9 16.0 1.7 2 0 0 2 2 2 0 SpoIIIAH-like protein AAA_11 PF13086.6 EAQ89459.1 - 0.92 9.2 6.5 5.7 6.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF5308 PF17233.2 EAQ89459.1 - 1.5 9.0 3.3 3 8.1 3.3 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5308) RNA_pol_Rpc4 PF05132.14 EAQ89459.1 - 1.6 9.2 8.0 3.7 8.0 8.0 1.6 1 0 0 1 1 1 0 RNA polymerase III RPC4 NPR3 PF03666.13 EAQ89459.1 - 3 6.5 7.8 4.6 5.9 7.8 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Nop14 PF04147.12 EAQ89459.1 - 7.3 4.7 20.1 12 4.0 20.1 1.2 1 0 0 1 1 1 0 Nop14-like family Methyltransf_23 PF13489.6 EAQ89460.1 - 2.8e-17 63.0 0.0 4.8e-17 62.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAQ89460.1 - 0.0014 18.5 0.0 0.17 11.7 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 EAQ89460.1 - 0.0026 18.4 0.0 0.6 10.8 0.0 2.6 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EAQ89460.1 - 0.055 14.1 0.0 0.74 10.5 0.0 2.4 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 EAQ89460.1 - 0.21 12.4 0.0 5.8 7.7 0.0 2.6 2 1 0 2 2 2 0 Methyltransferase domain DUF4246 PF14033.6 EAQ89461.1 - 2.4e-157 524.7 0.0 2.9e-157 524.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) Glyco_hydro_11 PF00457.17 EAQ89463.1 - 2.1e-59 200.1 10.3 2.5e-59 199.9 10.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 CHB_HEX_C_1 PF13290.6 EAQ89463.1 - 0.066 13.2 0.1 0.13 12.3 0.1 1.5 1 0 0 1 1 1 0 Chitobiase/beta-hexosaminidase C-terminal domain AAA_12 PF13087.6 EAQ89464.1 - 9.4e-36 123.3 0.0 2e-35 122.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAQ89464.1 - 9.1e-24 84.6 0.9 1.2e-22 81.0 0.9 2.3 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAQ89464.1 - 4.3e-09 36.9 0.2 3.4e-05 24.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 EAQ89464.1 - 1.7e-07 31.2 0.0 0.00015 21.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain DUF2075 PF09848.9 EAQ89464.1 - 0.017 14.4 0.1 0.035 13.3 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 EAQ89464.1 - 0.018 14.5 0.0 0.045 13.2 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein ResIII PF04851.15 EAQ89464.1 - 0.15 12.0 0.0 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit WD40 PF00400.32 EAQ89465.1 - 1.3e-05 25.9 2.1 1.6 9.7 0.3 4.9 5 0 0 5 5 5 2 WD domain, G-beta repeat CDC45 PF02724.14 EAQ89465.1 - 8.5 4.5 11.1 11 4.2 11.1 1.1 1 0 0 1 1 1 0 CDC45-like protein WD40 PF00400.32 EAQ89466.1 - 2.5e-19 69.2 2.3 4.6e-09 36.8 0.1 4.8 5 0 0 5 5 5 3 WD domain, G-beta repeat Ge1_WD40 PF16529.5 EAQ89466.1 - 1.1e-05 24.6 0.0 0.041 12.9 0.0 2.2 2 0 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 EAQ89466.1 - 4.8e-05 23.6 0.0 0.2 12.0 0.0 4.0 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain PUL PF08324.11 EAQ89467.1 - 2.4e-67 227.1 0.8 3.5e-67 226.6 0.8 1.3 1 0 0 1 1 1 1 PUL domain PFU PF09070.11 EAQ89467.1 - 9.2e-43 145.1 0.1 2e-42 144.0 0.1 1.6 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.32 EAQ89467.1 - 1.7e-25 88.8 13.3 7.6e-05 23.4 0.0 7.6 7 0 0 7 7 7 6 WD domain, G-beta repeat SRR1 PF07985.12 EAQ89469.1 - 2e-07 30.9 0.2 4.3e-07 29.9 0.2 1.6 1 1 0 1 1 1 1 SRR1 RPN2_C PF18004.1 EAQ89470.1 - 0.034 14.1 3.0 0.072 13.0 3.0 1.5 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain CDC45 PF02724.14 EAQ89470.1 - 0.079 11.2 3.3 0.12 10.7 3.3 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF3915 PF13054.6 EAQ89471.1 - 0.22 11.5 3.4 0.24 11.4 3.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Sox_N PF12444.8 EAQ89471.1 - 0.39 11.9 5.4 0.47 11.6 5.4 1.2 1 0 0 1 1 1 0 Sox developmental protein N terminal FAM176 PF14851.6 EAQ89471.1 - 1.6 8.3 5.5 1.6 8.4 5.5 1.0 1 0 0 1 1 1 0 FAM176 family Sporozoite_P67 PF05642.11 EAQ89471.1 - 1.7 6.6 8.4 1.8 6.6 8.4 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen AIM3 PF17096.5 EAQ89471.1 - 5.3 8.0 13.0 6.1 7.8 13.0 1.0 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 Methyltransf_11 PF08241.12 EAQ89472.1 - 3.1e-10 40.6 0.0 5.7e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAQ89472.1 - 1.8e-09 37.6 0.0 2.4e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAQ89472.1 - 5.9e-09 36.5 0.0 1.2e-08 35.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EAQ89472.1 - 9.1e-07 28.8 0.0 1.1e-06 28.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EAQ89472.1 - 0.00047 20.8 0.0 0.00077 20.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EAQ89472.1 - 0.00054 19.4 0.0 0.00079 18.8 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.15 EAQ89472.1 - 0.11 12.3 0.0 0.15 11.9 0.0 1.1 1 0 0 1 1 1 0 Hypothetical methyltransferase DUF3375 PF11855.8 EAQ89472.1 - 0.31 9.9 0.0 0.36 9.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3375) Striatin PF08232.12 EAQ89473.1 - 0.029 15.0 0.1 0.044 14.4 0.1 1.2 1 0 0 1 1 1 0 Striatin family ATG16 PF08614.11 EAQ89473.1 - 0.064 13.5 0.7 0.11 12.8 0.7 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) REV PF00424.18 EAQ89473.1 - 0.067 13.2 1.0 0.14 12.2 1.0 1.5 1 0 0 1 1 1 0 REV protein (anti-repression trans-activator protein) TolA_bind_tri PF16331.5 EAQ89473.1 - 0.081 13.0 0.8 0.12 12.4 0.8 1.3 1 0 0 1 1 1 0 TolA binding protein trimerisation DUF4407 PF14362.6 EAQ89473.1 - 0.17 11.2 0.2 0.23 10.8 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) NAD_binding_8 PF13450.6 EAQ89474.1 - 1.2e-10 41.4 0.0 1.1e-09 38.4 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EAQ89474.1 - 1.6e-07 30.8 0.0 1.6e-05 24.3 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EAQ89474.1 - 4e-07 29.5 0.0 5.8e-05 22.4 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 EAQ89474.1 - 2.4e-05 24.1 0.0 0.00077 19.1 0.0 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase FMO-like PF00743.19 EAQ89474.1 - 3e-05 22.6 0.1 0.00015 20.4 0.1 1.8 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Thi4 PF01946.17 EAQ89474.1 - 6e-05 22.4 0.0 0.00019 20.8 0.1 1.8 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.6 EAQ89474.1 - 0.00031 20.8 0.0 0.0033 17.4 0.0 2.4 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 EAQ89474.1 - 0.011 15.0 0.0 0.26 10.5 0.0 2.6 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EAQ89474.1 - 0.018 14.1 0.1 0.028 13.5 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 EAQ89474.1 - 0.034 13.2 0.1 0.18 10.8 0.1 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein CoA_binding PF02629.19 EAQ89474.1 - 0.16 12.6 0.0 0.9 10.3 0.0 2.1 2 0 0 2 2 2 0 CoA binding domain Tyrosinase PF00264.20 EAQ89475.1 - 5.8e-50 170.6 0.8 7.4e-50 170.3 0.8 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase DUF1100 PF06500.11 EAQ89475.1 - 0.076 11.8 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) Tho2 PF11262.8 EAQ89477.1 - 9.5 5.3 5.3 14 4.7 5.3 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 HrpB7 PF09486.10 EAQ89478.1 - 0.03 14.7 6.9 0.049 14.0 6.9 1.3 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) Pex14_N PF04695.13 EAQ89478.1 - 0.64 10.7 6.5 0.14 12.9 1.5 2.2 1 1 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SBF PF01758.16 EAQ89479.1 - 1.8e-52 177.9 14.1 1.8e-52 177.9 14.1 1.7 1 1 0 1 1 1 1 Sodium Bile acid symporter family SBF_like PF13593.6 EAQ89479.1 - 6.1e-10 38.9 25.1 8e-10 38.5 25.1 1.1 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) BBE PF08031.12 EAQ89480.1 - 0.0093 16.0 0.1 0.016 15.3 0.1 1.3 1 0 0 1 1 1 1 Berberine and berberine like FMN_red PF03358.15 EAQ89482.1 - 2.1e-20 73.1 0.0 2.8e-20 72.6 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase PAN_4 PF14295.6 EAQ89483.1 - 0.00017 21.5 3.9 0.00036 20.4 3.9 1.6 1 0 0 1 1 1 1 PAN domain Epimerase PF01370.21 EAQ89484.1 - 5.3e-08 32.6 0.0 1.1e-07 31.6 0.0 1.5 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EAQ89484.1 - 1.5e-05 24.9 0.0 2.6e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 EAQ89484.1 - 9e-05 21.8 0.0 0.00013 21.2 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Semialdhyde_dh PF01118.24 EAQ89484.1 - 0.00099 19.5 0.0 0.0017 18.8 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.10 EAQ89484.1 - 0.011 15.7 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 0 KR domain 3Beta_HSD PF01073.19 EAQ89484.1 - 0.1 11.6 0.0 0.14 11.2 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Myb_DNA-binding PF00249.31 EAQ89485.1 - 6.7e-28 96.6 10.9 6.8e-13 48.6 2.4 3.3 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAQ89485.1 - 1.7e-23 82.6 7.9 1.2e-13 51.1 0.4 3.2 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAQ89485.1 - 0.0014 18.5 0.0 0.16 11.9 0.0 2.2 2 0 0 2 2 2 1 Myb DNA-binding like SANT_DAMP1_like PF16282.5 EAQ89485.1 - 0.068 13.4 0.2 4.3 7.6 0.1 2.2 1 1 1 2 2 2 0 SANT/Myb-like domain of DAMP1 SLIDE PF09111.10 EAQ89485.1 - 0.22 11.6 0.0 9.8 6.2 0.0 2.2 2 0 0 2 2 2 0 SLIDE Rap1_C PF11626.8 EAQ89485.1 - 0.77 9.9 2.4 23 5.1 0.8 2.3 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Ferric_reduct PF01794.19 EAQ89486.1 - 5.9e-18 65.2 11.8 4.1e-17 62.5 9.5 2.6 2 0 0 2 2 2 1 Ferric reductase like transmembrane component DUF4413 PF14372.6 EAQ89486.1 - 0.00031 21.1 0.1 0.76 10.2 0.1 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF4413) zf-BED PF02892.15 EAQ89486.1 - 0.0023 17.9 0.4 0.0073 16.3 0.4 2.0 1 0 0 1 1 1 1 BED zinc finger FAD_binding_8 PF08022.12 EAQ89486.1 - 0.028 14.5 0.8 0.072 13.2 0.8 1.7 1 0 0 1 1 1 0 FAD-binding domain Vac7 PF12751.7 EAQ89486.1 - 0.032 13.7 0.1 0.19 11.1 0.0 2.0 2 0 0 2 2 2 0 Vacuolar segregation subunit 7 zf-RING_10 PF16685.5 EAQ89486.1 - 0.072 13.2 0.1 0.16 12.1 0.1 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 Glycoprot_B_PH2 PF17417.2 EAQ89486.1 - 0.086 13.2 0.2 0.53 10.6 0.1 2.2 2 0 0 2 2 2 0 Herpesvirus Glycoprotein B PH-like domain MFS_1 PF07690.16 EAQ89488.1 - 7.8e-21 74.4 31.7 2.4e-16 59.6 21.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily HET PF06985.11 EAQ89489.1 - 2e-10 41.2 0.0 3.2e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) RVT_2 PF07727.14 EAQ89491.1 - 4.4e-39 134.6 0.1 5e-38 131.1 0.0 2.2 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag_pre-integrs PF13976.6 EAQ89491.1 - 7.8e-08 32.1 0.1 1.6e-07 31.1 0.1 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain RVT_1 PF00078.27 EAQ89491.1 - 0.054 13.0 0.0 0.097 12.2 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) eIF3g PF12353.8 EAQ89492.1 - 0.0021 18.4 1.4 0.0034 17.8 0.2 2.0 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 3 subunit G DUF2113 PF09886.9 EAQ89492.1 - 0.041 13.2 0.0 0.072 12.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2113) APH PF01636.23 EAQ89494.1 - 7.8e-05 22.7 0.8 7.8e-05 22.7 0.8 2.0 2 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EAQ89494.1 - 0.11 12.1 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase FPN1 PF06963.12 EAQ89496.1 - 1.5e-58 198.4 0.3 2e-58 198.0 0.3 1.0 1 0 0 1 1 1 1 Ferroportin1 (FPN1) MFS_1_like PF12832.7 EAQ89496.1 - 0.089 11.6 2.3 0.071 12.0 0.7 1.6 1 1 0 2 2 2 0 MFS_1 like family UPF0182 PF03699.13 EAQ89496.1 - 2 6.4 4.5 0.39 8.8 1.1 1.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0182) zf-C2H2_4 PF13894.6 EAQ89497.1 - 1.1e-05 25.8 12.0 0.31 12.0 0.5 4.3 4 0 0 4 4 4 3 C2H2-type zinc finger FGAR-AT_N PF18076.1 EAQ89497.1 - 0.07 13.1 0.3 0.16 11.9 0.3 1.5 1 0 0 1 1 1 0 Formylglycinamide ribonucleotide amidotransferase N-terminal zf-C2H2 PF00096.26 EAQ89497.1 - 0.6 10.7 14.1 6 7.5 0.5 4.7 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EAQ89497.1 - 4.8 7.8 9.3 0.66 10.5 1.0 3.4 3 0 0 3 3 3 0 Zinc-finger double domain Fungal_trans PF04082.18 EAQ89498.1 - 2.2e-19 69.5 0.3 2.2e-19 69.5 0.3 2.0 3 0 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EAQ89498.1 - 2.8e-07 30.6 12.1 5.6e-07 29.6 12.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Spt20 PF12090.8 EAQ89498.1 - 0.036 13.7 13.1 0.058 13.0 13.1 1.3 1 0 0 1 1 1 0 Spt20 family Ndc1_Nup PF09531.10 EAQ89498.1 - 5.7 5.5 5.9 9.2 4.8 5.9 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Brr6_like_C_C PF10104.9 EAQ89499.1 - 1.7e-41 141.1 0.0 2.2e-41 140.8 0.0 1.1 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain Med26 PF08711.11 EAQ89500.1 - 1.1e-11 44.6 0.0 2.2e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Pkinase PF00069.25 EAQ89501.1 - 2.4e-41 141.9 0.3 9.6e-23 80.9 0.2 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ89501.1 - 1.6e-14 53.8 0.6 6.7e-10 38.7 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 EAQ89501.1 - 0.12 11.2 0.5 0.24 10.1 0.2 1.3 1 1 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 EAQ89501.1 - 0.15 11.4 0.0 2.5 7.4 0.0 2.4 3 0 0 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family Cupin_1 PF00190.22 EAQ89502.1 - 1.7e-12 47.2 0.0 2.3e-12 46.7 0.0 1.1 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 EAQ89502.1 - 0.00014 21.5 0.0 0.00071 19.2 0.0 2.0 1 1 0 1 1 1 1 Cupin domain Glyco_hydro_61 PF03443.14 EAQ89503.1 - 3.6e-47 161.0 0.0 4.6e-47 160.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 eIF3g PF12353.8 EAQ89505.1 - 0.0016 18.8 0.5 0.0062 16.9 0.5 2.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G DUF2113 PF09886.9 EAQ89505.1 - 0.048 13.0 0.0 0.097 12.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2113) RT_RNaseH PF17917.1 EAQ89506.1 - 3.8e-37 126.8 0.1 8.1e-37 125.7 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 EAQ89506.1 - 1.2e-34 118.3 0.0 2.9e-34 117.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 EAQ89506.1 - 4e-26 91.9 0.0 1e-25 90.6 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 EAQ89506.1 - 3.7e-14 52.6 0.0 1.5e-13 50.6 0.0 2.1 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 EAQ89506.1 - 6.5e-10 39.2 0.1 2.4e-09 37.4 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.24 EAQ89506.1 - 3.3e-08 33.3 2.5 7.9e-08 32.1 2.5 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 EAQ89506.1 - 0.013 15.8 0.0 0.04 14.1 0.0 1.8 1 0 0 1 1 1 0 H2C2 zinc finger Chromo_shadow PF01393.19 EAQ89506.1 - 0.16 12.1 0.1 0.43 10.7 0.1 1.7 1 0 0 1 1 1 0 Chromo shadow domain IN_DBD_C PF00552.21 EAQ89506.1 - 0.25 10.7 2.3 0.27 10.5 0.1 2.1 2 0 0 2 2 2 0 Integrase DNA binding domain zf-CCHC PF00098.23 EAQ89507.1 - 0.0027 17.7 0.1 0.0055 16.7 0.1 1.6 1 0 0 1 1 1 1 Zinc knuckle AAA_13 PF13166.6 EAQ89507.1 - 0.0071 15.0 1.7 0.0096 14.6 0.2 1.7 2 0 0 2 2 2 1 AAA domain ATG16 PF08614.11 EAQ89507.1 - 0.01 16.1 0.1 0.027 14.7 0.1 1.7 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) BRE1 PF08647.11 EAQ89507.1 - 0.017 15.2 0.9 0.04 14.0 0.9 1.6 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase Retrotrans_gag PF03732.17 EAQ89507.1 - 0.02 15.2 0.1 0.08 13.2 0.1 2.1 1 0 0 1 1 1 0 Retrotransposon gag protein SlyX PF04102.12 EAQ89507.1 - 0.027 15.1 0.3 0.11 13.1 0.3 2.1 1 0 0 1 1 1 0 SlyX DUF5082 PF16888.5 EAQ89507.1 - 0.043 14.1 1.9 0.085 13.1 0.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) zf-CCHC_2 PF13696.6 EAQ89507.1 - 0.047 13.5 0.4 0.081 12.8 0.4 1.4 1 0 0 1 1 1 0 Zinc knuckle Taxilin PF09728.9 EAQ89507.1 - 0.055 12.6 0.3 0.53 9.4 0.3 2.2 1 1 0 1 1 1 0 Myosin-like coiled-coil protein UPF0242 PF06785.11 EAQ89507.1 - 0.055 13.6 0.4 0.11 12.6 0.4 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Spc7 PF08317.11 EAQ89507.1 - 0.091 11.6 1.0 0.18 10.6 1.0 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4407 PF14362.6 EAQ89507.1 - 0.11 11.8 1.0 0.24 10.7 1.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ABC_tran_CTD PF16326.5 EAQ89507.1 - 0.57 10.5 4.8 0.72 10.2 2.7 2.2 2 0 0 2 2 2 0 ABC transporter C-terminal domain DivIC PF04977.15 EAQ89507.1 - 1.4 8.8 3.0 3.4 7.5 0.1 2.5 1 1 1 2 2 2 0 Septum formation initiator TMF_DNA_bd PF12329.8 EAQ89507.1 - 7.7 6.6 7.1 1.2 9.2 1.4 2.4 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding RVT_2 PF07727.14 EAQ89508.1 - 2.1e-38 132.4 0.0 5.2e-38 131.1 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 EAQ89508.1 - 0.054 13.0 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Pec_lyase_C PF00544.19 EAQ89510.1 - 2.4e-41 141.6 6.2 4.1e-41 140.9 6.2 1.4 1 0 0 1 1 1 1 Pectate lyase LDB19 PF13002.7 EAQ89510.1 - 0.099 12.3 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Arrestin_N terminal like DUF3328 PF11807.8 EAQ89512.1 - 3.8e-41 141.3 0.3 1.6e-40 139.2 0.0 1.9 1 1 1 2 2 2 1 Domain of unknown function (DUF3328) CFEM PF05730.11 EAQ89514.1 - 4.8e-20 71.4 7.4 8.3e-20 70.7 7.4 1.4 1 0 0 1 1 1 1 CFEM domain FAD_binding_4 PF01565.23 EAQ89515.1 - 4e-15 55.8 3.6 8.8e-15 54.7 2.2 2.2 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 EAQ89515.1 - 1.7e-08 34.5 0.1 4.1e-08 33.2 0.1 1.7 2 0 0 2 2 2 1 Berberine and berberine like RXLR PF16810.5 EAQ89516.1 - 0.15 12.5 0.3 0.28 11.6 0.3 1.4 1 0 0 1 1 1 0 RXLR phytopathogen effector protein, Avirulence activity Tyrosinase PF00264.20 EAQ89518.1 - 1.7e-53 182.2 0.1 2.1e-53 181.9 0.1 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase RAC_head PF16717.5 EAQ89520.1 - 4.8e-32 110.8 3.0 4.8e-32 110.8 3.0 3.5 3 1 1 4 4 4 1 Ribosome-associated complex head domain DnaJ PF00226.31 EAQ89520.1 - 3.3e-18 65.6 1.9 1.9e-17 63.2 1.9 2.4 1 0 0 1 1 1 1 DnaJ domain LMBR1 PF04791.16 EAQ89520.1 - 9.2 5.0 7.0 10 4.9 7.0 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein RRM_1 PF00076.22 EAQ89521.1 - 2.9e-10 39.8 0.0 5e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EAQ89521.1 - 5.6e-05 23.0 0.1 0.0001 22.2 0.1 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 EAQ89521.1 - 0.035 14.0 0.0 0.056 13.3 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif RRM_3 PF08777.11 EAQ89521.1 - 0.043 13.9 0.0 0.092 12.8 0.0 1.5 1 0 0 1 1 1 0 RNA binding motif Sterol_MT_C PF08498.10 EAQ89522.1 - 5.1e-28 97.2 0.5 9.1e-28 96.4 0.5 1.4 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 EAQ89522.1 - 4.8e-21 75.2 0.0 8.9e-21 74.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAQ89522.1 - 1.2e-19 70.8 0.0 2.7e-19 69.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAQ89522.1 - 2.3e-17 63.2 0.0 3.5e-17 62.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EAQ89522.1 - 7.8e-13 48.3 0.2 1.2e-12 47.7 0.2 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 EAQ89522.1 - 1.9e-11 44.1 0.0 2.9e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EAQ89522.1 - 4.4e-11 43.4 0.0 1.3e-10 41.9 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EAQ89522.1 - 1.7e-10 40.7 0.0 3.4e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.13 EAQ89522.1 - 0.00064 19.2 0.2 0.0018 17.7 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 EAQ89522.1 - 0.00083 18.9 0.0 0.0015 18.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain MetW PF07021.12 EAQ89522.1 - 0.0012 18.5 0.0 0.0018 17.9 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_15 PF09445.10 EAQ89522.1 - 0.0014 18.2 0.1 0.0022 17.6 0.1 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PCMT PF01135.19 EAQ89522.1 - 0.0036 17.1 0.0 0.0059 16.4 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_29 PF03141.16 EAQ89522.1 - 0.017 13.7 0.0 0.025 13.1 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_4 PF02390.17 EAQ89522.1 - 0.028 13.9 0.0 0.077 12.5 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_24 PF13578.6 EAQ89522.1 - 0.077 14.0 0.0 0.3 12.1 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain NodS PF05401.11 EAQ89522.1 - 0.092 12.3 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) Transket_pyr PF02779.24 EAQ89523.1 - 1.8e-45 154.8 0.0 2.5e-45 154.3 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EAQ89523.1 - 4.1e-34 117.1 0.0 1.3e-33 115.5 0.0 1.9 1 0 0 1 1 1 1 Transketolase, C-terminal domain Spore_IV_A PF09547.10 EAQ89523.1 - 0.012 14.6 0.0 0.02 13.9 0.0 1.2 1 0 0 1 1 1 0 Stage IV sporulation protein A (spore_IV_A) FtsA PF14450.6 EAQ89523.1 - 0.15 12.5 0.0 0.58 10.6 0.0 1.9 2 1 0 2 2 2 0 Cell division protein FtsA VIR_N PF15912.5 EAQ89524.1 - 0.066 12.8 4.0 0.038 13.6 1.9 1.5 2 0 0 2 2 2 0 Virilizer, N-terminal Glyco_hydro_61 PF03443.14 EAQ89525.1 - 1.3e-43 149.3 0.0 1.7e-43 149.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 AIG2_2 PF13772.6 EAQ89526.1 - 3e-05 24.3 0.1 0.00027 21.3 0.1 2.1 1 1 0 1 1 1 1 AIG2-like family GGACT PF06094.12 EAQ89526.1 - 4.3e-05 24.1 0.0 0.00016 22.2 0.0 1.9 1 1 0 2 2 2 1 Gamma-glutamyl cyclotransferase, AIG2-like SLC35F PF06027.12 EAQ89527.1 - 2.8e-98 329.1 19.7 3.5e-98 328.8 19.7 1.1 1 0 0 1 1 1 1 Solute carrier family 35 CRT-like PF08627.10 EAQ89527.1 - 6.7e-09 35.1 1.7 6.7e-09 35.1 1.7 1.6 2 0 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 EAQ89527.1 - 9e-07 29.1 32.8 0.0033 17.6 10.0 2.4 2 0 0 2 2 2 2 EamA-like transporter family FUSC-like PF12805.7 EAQ89527.1 - 0.0017 17.5 0.9 0.0017 17.5 0.9 2.0 2 0 0 2 2 2 1 FUSC-like inner membrane protein yccS CALM_bind PF16025.5 EAQ89528.1 - 0.012 16.1 1.0 0.021 15.3 1.0 1.4 1 0 0 1 1 1 0 Calcium-dependent calmodulin binding baeRF_family12 PF18856.1 EAQ89528.1 - 0.52 10.9 2.4 0.59 10.7 0.1 2.3 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 12 CVNH PF08881.10 EAQ89529.1 - 1.6e-33 115.4 0.1 2.9e-33 114.6 0.1 1.4 1 0 0 1 1 1 1 CVNH domain LysM PF01476.20 EAQ89529.1 - 2.3e-15 56.3 0.0 4.4e-15 55.5 0.0 1.5 1 0 0 1 1 1 1 LysM domain Rick_17kDa_Anti PF05433.15 EAQ89529.1 - 8.2e-09 35.2 16.7 8.2e-09 35.2 16.7 2.1 2 0 0 2 2 2 1 Glycine zipper 2TM domain Gly-zipper_YMGG PF13441.6 EAQ89529.1 - 0.00028 20.5 16.2 0.00075 19.2 16.2 1.7 1 0 0 1 1 1 1 YMGG-like Gly-zipper DUF533 PF04391.12 EAQ89529.1 - 0.0078 15.8 0.4 0.0078 15.8 0.4 1.7 2 0 0 2 2 1 1 Protein of unknown function (DUF533) CCDC71L PF15374.6 EAQ89529.1 - 1.2 8.3 6.9 1.6 7.9 6.9 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 71L CDC45 PF02724.14 EAQ89529.1 - 3.1 6.0 16.6 4.4 5.5 16.6 1.1 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 EAQ89529.1 - 4.1 7.1 15.3 0.29 10.9 10.6 1.4 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 LRIF1 PF15741.5 EAQ89529.1 - 5.8 5.3 6.9 7.4 5.0 6.9 1.1 1 0 0 1 1 1 0 Ligand-dependent nuclear receptor-interacting factor 1 FAM76 PF16046.5 EAQ89529.1 - 6.7 6.0 13.3 12 5.1 13.3 1.4 1 0 0 1 1 1 0 FAM76 protein MCM_bind PF09739.9 EAQ89529.1 - 9.8 4.5 10.1 12 4.2 10.1 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor SH3_3 PF08239.11 EAQ89531.1 - 0.00068 19.9 0.1 0.0016 18.7 0.1 1.6 1 0 0 1 1 1 1 Bacterial SH3 domain SH3_4 PF06347.13 EAQ89531.1 - 0.0083 15.9 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 Bacterial SH3 domain PAP_assoc PF03828.19 EAQ89532.1 - 1.2e-18 67.1 0.1 2.8e-18 65.9 0.1 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase Abhydrolase_1 PF00561.20 EAQ89534.1 - 3.4e-40 138.3 0.0 1.1e-39 136.6 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 EAQ89534.1 - 8.8e-05 22.3 0.0 0.00015 21.5 0.0 1.4 1 0 0 1 1 1 1 Putative esterase MFS_1 PF07690.16 EAQ89536.1 - 9.3e-21 74.1 31.4 8.8e-17 61.0 17.9 3.7 2 1 2 4 4 4 3 Major Facilitator Superfamily malic PF00390.19 EAQ89536.1 - 0.26 11.0 0.1 0.44 10.3 0.1 1.2 1 0 0 1 1 1 0 Malic enzyme, N-terminal domain Beta_helix PF13229.6 EAQ89539.1 - 9.7e-05 22.3 13.2 0.021 14.7 13.2 2.9 1 1 0 1 1 1 1 Right handed beta helix region LysM PF01476.20 EAQ89539.1 - 0.00025 21.0 0.0 0.21 11.7 0.0 3.1 3 0 0 3 3 3 2 LysM domain Glyco_hydro_43 PF04616.14 EAQ89540.1 - 5.8e-52 176.8 5.3 1e-51 176.0 5.2 1.4 2 0 0 2 2 2 1 Glycosyl hydrolases family 43 CBM_6 PF03422.15 EAQ89540.1 - 3.4e-28 98.5 3.8 4.1e-27 94.9 1.8 2.4 1 1 1 2 2 2 1 Carbohydrate binding module (family 6) APH PF01636.23 EAQ89540.1 - 8.1e-06 25.9 0.1 1.5e-05 25.0 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF5010_C PF18099.1 EAQ89540.1 - 0.00012 22.2 0.6 0.00023 21.3 0.6 1.5 1 0 0 1 1 1 1 DUF5010 C-terminal domain Glyco_hydro_32N PF00251.20 EAQ89540.1 - 0.0048 16.5 4.0 0.0096 15.5 4.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Choline_kinase PF01633.20 EAQ89540.1 - 0.05 13.2 0.0 0.083 12.5 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF1631 PF07793.11 EAQ89544.1 - 0.042 12.3 1.2 2.9 6.2 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1631) Keratin_2_head PF16208.5 EAQ89544.1 - 5.6 7.1 35.0 3 8.0 19.7 2.3 2 0 0 2 2 2 0 Keratin type II head IBB PF01749.20 EAQ89545.1 - 0.12 12.8 1.1 0.45 11.0 1.1 2.0 1 0 0 1 1 1 0 Importin beta binding domain SIR2 PF02146.17 EAQ89546.1 - 5.8e-39 133.8 0.0 1.4e-34 119.6 0.0 2.2 1 1 1 2 2 2 2 Sir2 family TPP_enzyme_M PF00205.22 EAQ89546.1 - 0.016 15.0 0.0 0.59 9.9 0.0 2.9 3 0 0 3 3 3 0 Thiamine pyrophosphate enzyme, central domain Cep57_CLD_2 PF14197.6 EAQ89546.1 - 0.15 12.2 1.4 0.29 11.3 1.4 1.4 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 DMPK_coil PF08826.10 EAQ89546.1 - 0.18 11.9 1.1 0.33 11.1 1.1 1.4 1 0 0 1 1 1 0 DMPK coiled coil domain like RP-C_C PF11800.8 EAQ89546.1 - 0.25 11.4 1.6 0.38 10.8 1.6 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region NDC10_II PF16787.5 EAQ89547.1 - 5e-62 209.8 0.0 9.5e-35 120.2 0.0 2.1 1 1 1 2 2 2 2 Centromere DNA-binding protein complex CBF3 subunit, domain 2 GCR1_C PF12550.8 EAQ89547.1 - 4e-19 68.7 0.5 1e-18 67.4 0.2 1.8 2 0 0 2 2 2 1 Transcriptional activator of glycolytic enzymes Arginosuc_synth PF00764.19 EAQ89548.1 - 7.7e-101 338.2 0.0 1.2e-78 265.2 0.0 2.0 2 0 0 2 2 2 2 Arginosuccinate synthase QueC PF06508.13 EAQ89548.1 - 0.00082 18.9 0.0 0.0014 18.1 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 EAQ89548.1 - 0.0033 16.3 0.0 0.0046 15.8 0.0 1.2 1 0 0 1 1 1 1 tRNA methyl transferase Asn_synthase PF00733.21 EAQ89548.1 - 0.011 15.4 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 0 Asparagine synthase FHA PF00498.26 EAQ89551.1 - 1.1e-16 60.9 0.1 2.2e-16 59.9 0.1 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EAQ89551.1 - 0.00032 20.9 0.0 0.00076 19.7 0.0 1.6 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain YhfZ_C PF14503.6 EAQ89551.1 - 0.033 13.7 0.0 0.062 12.8 0.0 1.3 1 0 0 1 1 1 0 YhfZ C-terminal domain GAS PF13851.6 EAQ89551.1 - 1.3 8.4 17.0 0.1 11.9 6.7 2.4 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Romo1 PF10247.9 EAQ89552.1 - 1.8e-09 37.8 2.5 2.1e-09 37.6 2.5 1.1 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 CEND1 PF15677.5 EAQ89552.1 - 0.13 12.8 0.3 0.14 12.7 0.3 1.0 1 0 0 1 1 1 0 Cell cycle exit and neuronal differentiation protein 1 Cu-oxidase_3 PF07732.15 EAQ89553.1 - 6.8e-40 135.8 7.3 4.9e-39 133.0 0.1 3.4 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.22 EAQ89553.1 - 1.4e-32 113.0 0.2 1.5e-30 106.4 0.0 2.4 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 EAQ89553.1 - 1.7e-30 105.5 9.7 3.3e-30 104.6 3.6 3.1 3 0 0 3 3 3 1 Multicopper oxidase DUF4982 PF16355.5 EAQ89553.1 - 0.055 13.4 0.1 0.12 12.3 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4982) TP_methylase PF00590.20 EAQ89554.1 - 1.7e-44 152.3 0.1 3.3e-44 151.4 0.1 1.5 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Sirohm_synth_C PF14823.6 EAQ89554.1 - 3.3e-12 45.8 0.0 7.4e-12 44.7 0.0 1.6 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 EAQ89554.1 - 6.8e-09 35.0 0.1 1.4e-08 34.0 0.1 1.6 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central NAD_binding_7 PF13241.6 EAQ89554.1 - 2.2e-06 28.0 0.0 9e-06 26.1 0.0 1.9 1 1 0 1 1 1 1 Putative NAD(P)-binding Ras PF00071.22 EAQ89555.1 - 3.4e-54 182.8 0.0 3.9e-54 182.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAQ89555.1 - 1.8e-21 76.6 0.0 3.4e-21 75.7 0.0 1.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAQ89555.1 - 1.2e-09 37.8 0.0 2e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 EAQ89555.1 - 0.0022 17.2 0.0 0.0026 17.0 0.0 1.2 1 0 0 1 1 1 1 G-protein alpha subunit Gtr1_RagA PF04670.12 EAQ89555.1 - 0.0031 16.9 0.0 0.0037 16.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EAQ89555.1 - 0.0096 15.4 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EAQ89555.1 - 0.027 14.5 0.0 0.047 13.8 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.27 EAQ89555.1 - 0.11 13.0 0.0 0.16 12.5 0.0 1.4 1 0 0 1 1 1 0 ABC transporter CWC25 PF12542.8 EAQ89556.1 - 3.6e-24 85.6 1.0 3.6e-24 85.6 1.0 4.3 4 2 0 4 4 4 1 Pre-mRNA splicing factor Cir_N PF10197.9 EAQ89556.1 - 2.1e-09 37.4 5.3 2.1e-09 37.4 5.3 4.5 5 1 0 5 5 5 1 N-terminal domain of CBF1 interacting co-repressor CIR PCI PF01399.27 EAQ89557.1 - 8.6e-19 68.0 0.2 3.8e-18 65.9 0.0 2.2 2 1 0 2 2 2 1 PCI domain TPR_12 PF13424.6 EAQ89557.1 - 0.14 12.5 0.7 12 6.2 0.2 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 EAQ89557.1 - 0.36 10.7 2.9 1.9 8.4 0.7 3.0 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 EAQ89557.1 - 2.2 8.6 6.4 0.89 9.8 0.7 3.4 3 1 0 3 3 3 0 Tetratricopeptide repeat DOG1 PF14144.6 EAQ89559.1 - 0.05 13.8 0.0 0.071 13.3 0.0 1.3 1 0 0 1 1 1 0 Seed dormancy control Peptidase_C65 PF10275.9 EAQ89560.1 - 1.5e-71 240.8 0.0 1.9e-71 240.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase C65 Otubain ETX_MTX2 PF03318.13 EAQ89560.1 - 0.014 15.2 0.8 4.3 7.0 0.3 2.6 3 0 0 3 3 3 0 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 PLRV_ORF5 PF01690.17 EAQ89560.1 - 0.16 10.7 2.0 0.26 9.9 2.0 1.3 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein BPL_LplA_LipB PF03099.19 EAQ89561.1 - 0.00022 21.1 0.0 0.00035 20.5 0.0 1.2 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Rsm22 PF09243.10 EAQ89562.1 - 1.4e-30 106.5 0.0 4.9e-30 104.7 0.0 1.8 1 1 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_23 PF13489.6 EAQ89562.1 - 0.025 14.4 0.0 0.089 12.6 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 EAQ89562.1 - 0.081 13.7 0.0 0.25 12.1 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain SelK_SelG PF10961.8 EAQ89563.1 - 0.001 19.6 0.1 0.001 19.6 0.1 2.2 1 1 1 2 2 2 1 Selenoprotein SelK_SelG Methyltrn_RNA_3 PF02598.17 EAQ89564.1 - 2.9e-100 335.5 0.0 3.3e-100 335.3 0.0 1.0 1 0 0 1 1 1 1 Putative RNA methyltransferase SpoU_methylase PF00588.19 EAQ89564.1 - 0.033 14.4 0.0 0.095 12.9 0.0 1.7 2 0 0 2 2 2 0 SpoU rRNA Methylase family Spore_YabQ PF09578.10 EAQ89565.1 - 0.055 13.7 1.1 0.068 13.4 1.1 1.2 1 0 0 1 1 1 0 Spore cortex protein YabQ (Spore_YabQ) Atg8 PF02991.16 EAQ89567.1 - 0.092 12.9 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 Autophagy protein Atg8 ubiquitin like CPSase_L_D2 PF02786.17 EAQ89568.1 - 4.2e-74 248.6 0.0 6.7e-74 247.9 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 EAQ89568.1 - 5.1e-38 130.0 0.0 1.2e-37 128.9 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 EAQ89568.1 - 1.3e-37 128.1 0.0 3e-37 127.0 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 EAQ89568.1 - 3.7e-15 55.5 0.8 9.2e-15 54.2 0.8 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp PF02222.22 EAQ89568.1 - 5.1e-08 32.7 0.0 9.5e-08 31.8 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 EAQ89568.1 - 6e-07 29.2 0.0 1.3e-06 28.1 0.0 1.5 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.6 EAQ89568.1 - 2.8e-06 27.0 0.1 0.035 13.9 0.0 3.2 2 1 1 3 3 3 2 Biotin-lipoyl like ATP-grasp_3 PF02655.14 EAQ89568.1 - 3.4e-05 24.0 0.0 7.1e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.6 EAQ89568.1 - 0.012 16.4 0.1 3.9 8.2 0.0 2.8 2 0 0 2 2 2 0 HlyD family secretion protein HlyD_D23 PF16576.5 EAQ89568.1 - 0.028 13.6 0.1 3 7.0 0.0 2.4 1 1 1 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion ATPgrasp_ST PF14397.6 EAQ89568.1 - 0.062 12.5 0.0 0.22 10.7 0.0 1.8 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp ATP-grasp_4 PF13535.6 EAQ89568.1 - 0.14 11.7 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain Putative_PNPOx PF01243.20 EAQ89569.1 - 2.1e-13 50.2 0.0 2e-12 47.1 0.0 2.1 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.7 EAQ89569.1 - 0.0021 18.1 0.0 0.15 12.1 0.0 2.1 1 1 1 2 2 2 2 Pyridoxamine 5'-phosphate oxidase Mem_trans PF03547.18 EAQ89570.1 - 5e-49 166.7 0.8 1.3e-29 102.8 0.0 2.0 2 0 0 2 2 2 2 Membrane transport protein Pkinase PF00069.25 EAQ89571.1 - 1.5e-37 129.4 0.0 1.2e-34 119.9 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ89571.1 - 7e-21 74.7 0.0 1.7e-19 70.1 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Seadorna_VP7 PF07387.11 EAQ89571.1 - 0.0011 18.1 0.1 0.0018 17.4 0.1 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Haspin_kinase PF12330.8 EAQ89571.1 - 0.0024 16.9 0.0 0.0035 16.4 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 EAQ89571.1 - 0.065 12.0 0.0 0.086 11.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 EAQ89571.1 - 0.15 12.0 0.2 0.54 10.1 0.1 1.9 1 1 0 1 1 1 0 Phosphotransferase enzyme family SUR7 PF06687.12 EAQ89572.1 - 7.3e-41 140.1 5.6 8.5e-41 139.9 5.6 1.0 1 0 0 1 1 1 1 SUR7/PalI family Clc-like PF07062.12 EAQ89572.1 - 0.093 12.2 5.5 0.16 11.4 5.5 1.4 1 0 0 1 1 1 0 Clc-like Amastin PF07344.11 EAQ89572.1 - 0.19 11.6 10.8 0.38 10.6 10.8 1.4 1 0 0 1 1 1 0 Amastin surface glycoprotein DUF373 PF04123.13 EAQ89572.1 - 0.34 10.3 2.5 0.6 9.5 2.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF373) Cytochrome-c551 PF10643.9 EAQ89572.1 - 6.1 6.4 6.6 11 5.6 6.6 1.3 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 ACPS PF01648.20 EAQ89573.1 - 1.8e-08 34.5 0.0 3.3e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Peptidase_A22B PF04258.13 EAQ89574.1 - 2.7e-53 181.3 7.5 1.7e-33 116.4 4.1 2.1 2 0 0 2 2 2 2 Signal peptide peptidase TFIIS_C PF01096.18 EAQ89575.1 - 7.4e-21 73.7 2.8 7.4e-21 73.7 2.8 2.5 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 EAQ89575.1 - 1.2e-08 34.6 0.3 1.2e-08 34.6 0.3 2.7 4 0 0 4 4 4 1 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.7 EAQ89575.1 - 0.0052 16.7 5.6 0.23 11.4 0.2 2.5 2 1 0 2 2 2 2 Transposase zinc-ribbon domain IBR PF01485.21 EAQ89575.1 - 0.0093 16.2 6.2 0.11 12.7 2.1 2.4 2 1 0 2 2 2 2 IBR domain, a half RING-finger domain zf-RING_12 PF17976.1 EAQ89575.1 - 0.35 11.2 3.9 1.5 9.1 0.6 2.4 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-H2C2_2 PF13465.6 EAQ89575.1 - 4.5 7.9 10.6 34 5.1 0.0 3.9 4 0 0 4 4 4 0 Zinc-finger double domain Ank_2 PF12796.7 EAQ89576.1 - 4.9e-05 23.8 0.0 9e-05 23.0 0.0 1.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAQ89576.1 - 7.3e-05 23.2 0.0 0.0031 18.0 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 EAQ89576.1 - 0.00098 19.5 0.0 0.53 10.8 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 EAQ89576.1 - 0.0021 18.4 0.1 1.2 9.9 0.0 3.0 3 1 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 EAQ89576.1 - 0.018 15.4 0.0 4.3 7.8 0.0 2.6 2 1 0 2 2 2 0 Ankyrin repeats (many copies) Gar1 PF04410.14 EAQ89576.1 - 0.22 11.3 1.6 0.28 10.9 1.6 1.2 1 0 0 1 1 1 0 Gar1/Naf1 RNA binding region HSP70 PF00012.20 EAQ89577.1 - 3.1e-11 42.2 0.3 1e-09 37.2 0.1 2.0 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 EAQ89577.1 - 0.027 13.3 0.1 0.16 10.8 0.0 1.9 2 0 0 2 2 2 0 MreB/Mbl protein Hexokinase_1 PF00349.21 EAQ89578.1 - 2.3e-77 259.4 0.1 3.2e-77 258.9 0.1 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.16 EAQ89578.1 - 1.4e-75 253.9 0.0 3.6e-75 252.5 0.0 1.7 2 0 0 2 2 2 1 Hexokinase Acetyltransf_1 PF00583.25 EAQ89579.1 - 0.001 19.3 0.0 0.0017 18.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EAQ89579.1 - 0.15 12.5 0.0 0.25 11.8 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Sgf11 PF08209.11 EAQ89580.1 - 0.0077 15.8 2.5 0.021 14.4 2.5 1.7 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) zf_UBZ PF18439.1 EAQ89580.1 - 0.31 10.7 2.0 1.2 8.8 0.3 2.2 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Pro_isomerase PF00160.21 EAQ89581.1 - 1.5e-52 178.1 0.0 1.7e-52 177.8 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD CFEM PF05730.11 EAQ89582.1 - 3.9e-10 39.7 12.2 6.5e-10 39.0 12.2 1.4 1 0 0 1 1 1 1 CFEM domain PAP1 PF08601.10 EAQ89582.1 - 0.65 9.7 8.8 0.72 9.5 8.8 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 Herpes_TAF50 PF03326.13 EAQ89582.1 - 1.8 7.1 11.6 2.5 6.7 11.6 1.2 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) Myosin_head PF00063.21 EAQ89584.1 - 1.6e-258 859.5 0.1 7.7e-258 857.2 0.1 2.2 1 1 0 1 1 1 1 Myosin head (motor domain) Myosin_N PF02736.19 EAQ89584.1 - 1.8e-13 50.0 0.3 4.6e-13 48.8 0.3 1.8 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Myosin_tail_1 PF01576.19 EAQ89584.1 - 6.2e-13 47.5 262.0 2.2e-11 42.4 109.0 6.1 2 2 1 3 3 3 2 Myosin tail Spc7 PF08317.11 EAQ89584.1 - 0.0015 17.5 22.0 0.0015 17.5 22.0 11.7 2 2 8 10 10 10 3 Spc7 kinetochore protein TsaE PF02367.17 EAQ89584.1 - 0.037 14.0 0.3 0.17 11.9 0.0 2.2 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 EAQ89584.1 - 0.16 12.3 0.0 0.16 12.3 0.0 4.8 4 0 0 4 4 4 0 AAA domain zf-C3H1 PF10650.9 EAQ89585.1 - 5.5e-07 29.2 4.2 8.6e-07 28.6 4.2 1.3 1 0 0 1 1 1 1 Putative zinc-finger domain DivIC PF04977.15 EAQ89585.1 - 0.085 12.6 1.5 0.35 10.7 1.5 2.0 1 0 0 1 1 1 0 Septum formation initiator Cluap1 PF10234.9 EAQ89585.1 - 1.8 7.9 5.4 0.5 9.7 2.3 1.6 2 0 0 2 2 2 0 Clusterin-associated protein-1 Upf2 PF04050.14 EAQ89585.1 - 2.3 8.9 10.1 0.12 13.1 0.8 3.3 2 0 0 2 2 2 0 Up-frameshift suppressor 2 4HBT_3 PF13622.6 EAQ89586.1 - 1.4e-66 225.3 0.3 1.8e-66 224.9 0.3 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 EAQ89586.1 - 1e-19 70.7 0.0 2.9e-11 43.3 0.0 3.2 3 0 0 3 3 3 2 Acyl-CoA thioesterase Ge1_WD40 PF16529.5 EAQ89586.1 - 0.087 11.8 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Oxysterol_BP PF01237.18 EAQ89587.1 - 2.4e-43 148.4 1.0 1.9e-41 142.2 0.0 2.3 2 0 0 2 2 2 1 Oxysterol-binding protein Ank_5 PF13857.6 EAQ89587.1 - 2.2e-17 62.9 0.6 1.7e-09 37.8 0.1 3.7 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 EAQ89587.1 - 1.3e-15 57.0 0.7 1.6e-05 25.1 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.7 EAQ89587.1 - 2.3e-14 53.7 0.0 1.2e-09 38.7 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) PH PF00169.29 EAQ89587.1 - 6.9e-12 45.8 1.0 1.2e-11 45.0 1.0 1.4 1 0 0 1 1 1 1 PH domain Ank_4 PF13637.6 EAQ89587.1 - 8.9e-12 45.3 0.0 6.1e-07 29.9 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAQ89587.1 - 3.2e-11 42.4 0.0 0.00019 21.6 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat PH_8 PF15409.6 EAQ89587.1 - 4e-08 33.4 1.1 9.8e-08 32.2 1.1 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 EAQ89587.1 - 9.5e-06 26.0 2.5 2.7e-05 24.5 2.5 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain PH_17 PF18012.1 EAQ89587.1 - 0.0071 16.0 0.0 0.016 14.9 0.0 1.6 1 0 0 1 1 1 1 PH domain EST1_DNA_bind PF10373.9 EAQ89589.1 - 5.9e-14 52.2 0.0 1.1e-13 51.4 0.0 1.4 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain Rad50_zn_hook PF04423.14 EAQ89589.1 - 0.11 12.4 0.1 0.26 11.2 0.1 1.5 1 0 0 1 1 1 0 Rad50 zinc hook motif zf-ribbon_3 PF13248.6 EAQ89589.1 - 0.15 11.5 1.2 0.29 10.6 0.2 2.1 2 0 0 2 2 2 0 zinc-ribbon domain Peptidase_S64 PF08192.11 EAQ89590.1 - 0.12 10.8 0.0 0.2 10.1 0.0 1.2 1 0 0 1 1 1 0 Peptidase family S64 Gly_transf_sug PF04488.15 EAQ89595.1 - 1.6e-14 54.3 0.0 3.7e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif AMP-binding PF00501.28 EAQ89596.1 - 2.3e-89 299.9 0.0 2.9e-89 299.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EAQ89596.1 - 2e-20 73.6 0.6 7.9e-20 71.6 0.6 2.1 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Mito_fiss_reg PF05308.11 EAQ89597.1 - 0.46 10.5 2.6 0.53 10.3 2.6 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EAQ89597.1 - 0.75 9.2 10.4 0.9 9.0 10.4 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal adh_short PF00106.25 EAQ89598.1 - 2.5e-51 173.9 1.4 3e-51 173.7 1.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EAQ89598.1 - 8.1e-46 156.5 0.9 9.2e-46 156.3 0.9 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EAQ89598.1 - 1.1e-12 48.2 0.5 1.8e-12 47.5 0.5 1.3 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 EAQ89598.1 - 3.7e-05 23.7 0.2 5.5e-05 23.1 0.2 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.21 EAQ89598.1 - 8.8e-05 22.1 1.8 0.00054 19.5 1.8 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EAQ89598.1 - 0.00012 21.1 0.1 0.00017 20.7 0.1 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family THF_DHG_CYH_C PF02882.19 EAQ89598.1 - 0.00024 20.5 0.0 0.00045 19.6 0.0 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GDP_Man_Dehyd PF16363.5 EAQ89598.1 - 0.00039 19.9 0.7 0.0014 18.1 0.0 1.9 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EAQ89598.1 - 0.0015 17.7 0.0 0.0022 17.2 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 EAQ89598.1 - 0.0033 16.6 0.1 0.0043 16.2 0.1 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Ldh_1_N PF00056.23 EAQ89598.1 - 0.026 14.6 0.2 0.046 13.8 0.2 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain DFP PF04127.15 EAQ89598.1 - 0.029 14.2 0.3 0.046 13.6 0.3 1.4 1 1 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein F420_oxidored PF03807.17 EAQ89598.1 - 0.031 14.8 0.0 0.056 14.0 0.0 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NmrA PF05368.13 EAQ89598.1 - 0.049 13.2 0.3 0.077 12.5 0.3 1.3 1 0 0 1 1 1 0 NmrA-like family 2-Hacid_dh_C PF02826.19 EAQ89598.1 - 0.072 12.4 0.1 0.11 11.8 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_4 PF07993.12 EAQ89598.1 - 0.11 11.7 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 Male sterility protein ApbA PF02558.16 EAQ89598.1 - 0.11 12.1 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA ThiF PF00899.21 EAQ89599.1 - 8.8e-39 133.3 0.0 1.4e-38 132.6 0.0 1.2 1 0 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 EAQ89599.1 - 0.00016 21.9 0.1 0.5 10.6 0.1 3.2 3 0 0 3 3 3 2 Saccharopine dehydrogenase NADP binding domain UDPG_MGDP_dh_N PF03721.14 EAQ89599.1 - 0.0048 16.5 0.1 0.01 15.4 0.1 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.18 EAQ89599.1 - 0.0058 16.9 0.1 0.024 14.9 0.1 2.1 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_7 PF13241.6 EAQ89599.1 - 0.023 15.1 0.0 0.06 13.8 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding ApbA PF02558.16 EAQ89599.1 - 0.16 11.6 0.1 0.28 10.8 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA RTC PF01137.21 EAQ89600.1 - 2.4e-50 170.8 0.0 3.2e-50 170.4 0.0 1.1 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase QRPTase_C PF01729.19 EAQ89603.1 - 1.2e-53 181.3 0.1 1.5e-53 181.0 0.1 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 EAQ89603.1 - 2.5e-18 65.9 0.0 6.8e-18 64.5 0.0 1.8 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain IGPS PF00218.21 EAQ89603.1 - 0.029 13.5 0.1 0.047 12.9 0.1 1.3 1 0 0 1 1 1 0 Indole-3-glycerol phosphate synthase Peripla_BP_6 PF13458.6 EAQ89603.1 - 0.037 13.7 0.0 0.049 13.3 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding protein RCC1 PF00415.18 EAQ89604.1 - 1.3e-52 176.2 11.2 1.3e-11 44.9 0.1 7.7 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EAQ89604.1 - 1e-39 133.5 26.2 3.8e-08 32.9 0.9 6.9 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat Hira PF07569.11 EAQ89604.1 - 0.0015 18.3 2.7 1.8 8.2 0.0 3.7 6 0 0 6 6 6 2 TUP1-like enhancer of split DUF3614 PF12267.8 EAQ89604.1 - 0.46 11.0 4.0 0.73 10.3 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3614) AA_kinase PF00696.28 EAQ89605.1 - 2.3e-33 115.8 0.1 1.2e-32 113.5 0.0 2.0 2 0 0 2 2 2 1 Amino acid kinase family Semialdhyde_dh PF01118.24 EAQ89605.1 - 2.9e-30 105.2 0.0 7.2e-30 103.9 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAT PF04768.13 EAQ89605.1 - 1.5e-26 93.1 0.0 2.9e-26 92.2 0.0 1.4 1 0 0 1 1 1 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase DapB_N PF01113.20 EAQ89605.1 - 0.18 11.9 0.0 0.44 10.7 0.0 1.7 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Synaptobrevin PF00957.21 EAQ89606.1 - 7.7e-16 57.7 0.0 8.8e-16 57.5 0.0 1.0 1 0 0 1 1 1 1 Synaptobrevin Radical_SAM PF04055.21 EAQ89607.1 - 2.6e-16 60.5 0.1 4e-16 59.9 0.1 1.3 1 0 0 1 1 1 1 Radical SAM superfamily LIAS_N PF16881.5 EAQ89607.1 - 2.2e-15 57.0 0.0 5.4e-15 55.7 0.0 1.7 2 0 0 2 2 2 1 N-terminal domain of lipoyl synthase of Radical_SAM family Ribosomal_S14 PF00253.21 EAQ89608.1 - 2.3e-22 78.5 0.5 4.6e-22 77.5 0.5 1.5 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Ank_4 PF13637.6 EAQ89609.1 - 9.4e-49 163.2 0.2 2.4e-13 50.3 0.0 5.4 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAQ89609.1 - 3.2e-39 133.4 0.0 1.1e-12 48.4 0.0 4.3 1 1 3 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAQ89609.1 - 3.1e-32 107.0 0.0 2.7e-05 24.2 0.0 6.7 7 0 0 7 7 7 5 Ankyrin repeat Ank PF00023.30 EAQ89609.1 - 2.9e-29 100.2 0.0 0.00032 21.0 0.0 6.9 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 EAQ89609.1 - 8.6e-27 92.9 0.0 3.6e-07 30.3 0.0 5.1 3 1 2 5 5 5 5 Ankyrin repeats (many copies) DUF5427 PF10310.9 EAQ89611.1 - 0.18 10.7 0.0 0.24 10.3 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5427) DUF4191 PF13829.6 EAQ89612.1 - 0.024 14.0 0.2 0.024 14.0 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) NST1 PF13945.6 EAQ89612.1 - 0.041 14.0 2.2 0.061 13.4 2.2 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator Herpes_LMP1 PF05297.11 EAQ89612.1 - 0.18 11.0 0.0 0.38 9.9 0.0 1.5 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) SWIRM-assoc_2 PF16496.5 EAQ89612.1 - 0.37 9.6 2.9 0.55 9.0 2.9 1.1 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal WD40 PF00400.32 EAQ89614.1 - 2e-08 34.7 9.9 0.0016 19.2 0.3 5.5 5 1 0 5 5 5 2 WD domain, G-beta repeat DEC-1_N PF04625.13 EAQ89616.1 - 6.9 5.6 9.1 8 5.4 9.1 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region RRM_1 PF00076.22 EAQ89618.1 - 1e-18 66.9 0.0 1.5e-12 47.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 EAQ89618.1 - 0.066 13.0 0.0 2.3 8.0 0.0 2.2 2 0 0 2 2 2 0 Rrp7 RRM-like N-terminal domain RRM_occluded PF16842.5 EAQ89618.1 - 0.12 12.3 0.0 0.34 10.8 0.0 1.7 2 0 0 2 2 2 0 Occluded RNA-recognition motif Zn_clus PF00172.18 EAQ89619.1 - 0.15 12.2 4.4 0.27 11.4 4.4 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Semialdhyde_dhC PF02774.18 EAQ89621.1 - 2.2e-40 138.7 0.0 3.1e-40 138.2 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 EAQ89621.1 - 1.3e-29 103.1 0.0 5.6e-29 101.0 0.0 1.9 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 EAQ89621.1 - 0.02 15.0 0.0 0.04 14.0 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Sacchrp_dh_NADP PF03435.18 EAQ89621.1 - 0.055 13.7 0.1 0.26 11.5 0.0 2.1 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain RhoGAP PF00620.27 EAQ89622.1 - 1.7e-26 92.8 0.6 1.1e-13 51.3 0.7 2.3 1 1 1 2 2 2 2 RhoGAP domain TPR_MLP1_2 PF07926.12 EAQ89622.1 - 0.055 13.5 0.2 0.055 13.5 0.2 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF5327 PF17261.2 EAQ89622.1 - 0.78 10.5 4.6 2.4 9.0 0.0 3.4 3 0 0 3 3 3 0 Family of unknown function (DUF5327) EMC1_C PF07774.13 EAQ89623.1 - 2.7e-80 269.1 0.0 3e-80 268.9 0.0 1.0 1 0 0 1 1 1 1 ER membrane protein complex subunit 1, C-terminal LRR_8 PF13855.6 EAQ89624.1 - 4.2e-07 29.6 7.2 0.00017 21.3 0.8 2.4 2 1 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 EAQ89624.1 - 0.011 16.1 4.3 0.028 14.9 0.2 3.0 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) FAR1 PF03101.15 EAQ89627.1 - 0.0013 19.4 0.2 0.0016 19.1 0.2 1.1 1 0 0 1 1 1 1 FAR1 DNA-binding domain Ank_2 PF12796.7 EAQ89630.1 - 2e-62 207.8 12.6 9.3e-12 45.4 0.0 8.3 2 1 8 10 10 10 10 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAQ89630.1 - 1.1e-36 124.8 7.2 3.1e-10 40.4 0.0 9.3 6 1 3 9 9 9 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAQ89630.1 - 3.6e-34 112.9 9.0 0.00099 19.4 0.0 12.6 13 0 0 13 13 13 8 Ankyrin repeat Ank PF00023.30 EAQ89630.1 - 8.7e-26 89.2 11.2 0.035 14.6 0.0 12.1 12 0 0 12 12 12 6 Ankyrin repeat Ank_5 PF13857.6 EAQ89630.1 - 7.6e-21 73.9 17.2 3.7e-07 30.3 0.1 10.2 8 3 4 12 12 12 6 Ankyrin repeats (many copies) ZZ PF00569.17 EAQ89630.1 - 0.0025 17.6 3.6 0.0063 16.3 3.6 1.6 1 0 0 1 1 1 1 Zinc finger, ZZ type Ank PF00023.30 EAQ89632.1 - 0.04 14.4 0.1 1.9 9.1 0.0 3.0 3 0 0 3 3 3 0 Ankyrin repeat tRNA-synt_2 PF00152.20 EAQ89633.1 - 2.1e-59 201.2 0.0 2.9e-59 200.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) NARP1 PF12569.8 EAQ89633.1 - 0.17 10.8 6.5 0.24 10.2 6.5 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Porin_5 PF16930.5 EAQ89633.1 - 0.46 8.9 4.9 0.66 8.4 4.9 1.1 1 0 0 1 1 1 0 Putative porin SIP1 PF04938.12 EAQ89634.1 - 0.00065 19.5 0.0 0.13 12.0 0.0 2.7 2 2 0 3 3 3 2 Survival motor neuron (SMN) interacting protein 1 (SIP1) RelB_transactiv PF16181.5 EAQ89634.1 - 0.046 14.0 1.5 0.066 13.5 0.1 1.9 2 0 0 2 2 2 0 RelB transactivation domain RNR_inhib PF08591.10 EAQ89635.1 - 2.9e-30 105.7 3.7 3.6e-30 105.4 0.0 2.7 3 0 0 3 3 3 1 Ribonucleotide reductase inhibitor Ribosomal_S27e PF01667.17 EAQ89636.1 - 2.4e-08 33.5 0.4 3.1e-08 33.2 0.4 1.2 1 0 0 1 1 1 1 Ribosomal protein S27 Phosducin PF02114.16 EAQ89637.1 - 1.5e-12 47.1 0.0 2.2e-12 46.5 0.0 1.2 1 0 0 1 1 1 1 Phosducin Thioredoxin PF00085.20 EAQ89637.1 - 0.15 12.1 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin TMA7 PF09072.10 EAQ89637.1 - 1 10.3 3.9 26 5.8 0.2 2.5 2 0 0 2 2 2 0 Translation machinery associated TMA7 Raptor_N PF14538.6 EAQ89638.1 - 5.1e-64 214.7 0.0 1e-63 213.7 0.0 1.5 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.32 EAQ89638.1 - 8.6e-08 32.7 6.8 4.7 8.3 0.0 7.1 6 1 0 6 6 6 2 WD domain, G-beta repeat BBS2_Mid PF14783.6 EAQ89638.1 - 3.3e-05 23.9 0.0 0.067 13.2 0.0 2.6 1 1 1 2 2 2 2 Ciliary BBSome complex subunit 2, middle region HEAT_2 PF13646.6 EAQ89638.1 - 0.025 14.9 0.8 2 8.9 0.0 3.6 3 1 1 4 4 4 0 HEAT repeats HEAT PF02985.22 EAQ89638.1 - 0.045 14.0 0.2 45 4.7 0.0 4.5 5 0 0 5 5 5 0 HEAT repeat Glyco_transf_25 PF01755.17 EAQ89639.1 - 3.2e-06 27.2 0.0 0.055 13.3 0.0 2.1 2 0 0 2 2 2 2 Glycosyltransferase family 25 (LPS biosynthesis protein) Collagen_bind PF05737.12 EAQ89639.1 - 0.17 12.1 0.2 0.39 10.9 0.2 1.6 2 0 0 2 2 2 0 Collagen binding domain DUF4352 PF11611.8 EAQ89640.1 - 0.14 12.5 0.2 1.7 9.0 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4352) Sporozoite_P67 PF05642.11 EAQ89640.1 - 0.34 9.0 9.8 0.44 8.6 9.8 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Kelch_4 PF13418.6 EAQ89641.1 - 4.5e-30 103.4 8.4 4.4e-06 26.6 1.1 6.5 4 2 2 6 6 6 6 Galactose oxidase, central domain Kelch_6 PF13964.6 EAQ89641.1 - 4e-28 96.7 5.7 2.6e-12 46.5 0.7 6.5 5 1 1 6 6 6 6 Kelch motif Kelch_1 PF01344.25 EAQ89641.1 - 2e-25 88.1 3.3 1.8e-11 43.4 0.2 6.4 6 0 0 6 6 6 4 Kelch motif Kelch_3 PF13415.6 EAQ89641.1 - 2.7e-25 88.1 5.9 5.1e-06 26.6 0.1 5.9 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.6 EAQ89641.1 - 4.9e-24 83.9 10.9 8.1e-08 32.1 0.1 6.3 5 1 0 5 5 5 5 Kelch motif Kelch_2 PF07646.15 EAQ89641.1 - 5.2e-16 57.9 4.9 1e-06 28.4 0.4 6.4 6 0 0 6 6 6 2 Kelch motif ATG16 PF08614.11 EAQ89641.1 - 0.0007 19.9 22.2 0.0007 19.9 22.2 6.7 5 1 1 7 7 7 1 Autophagy protein 16 (ATG16) YIF1 PF03878.15 EAQ89643.1 - 1.3e-96 322.8 2.3 1.6e-96 322.5 2.3 1.1 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.17 EAQ89643.1 - 9.9e-05 22.1 4.6 9.9e-05 22.1 4.6 1.5 2 0 0 2 2 2 1 Yip1 domain SRP-alpha_N PF04086.13 EAQ89644.1 - 7.4e-78 262.4 0.0 1e-77 262.0 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.22 EAQ89644.1 - 6.5e-53 179.3 0.2 1.1e-52 178.5 0.2 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.19 EAQ89644.1 - 7.1e-09 35.8 0.2 2.5e-08 34.0 0.2 2.0 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain MeaB PF03308.16 EAQ89644.1 - 4.3e-06 25.9 0.0 8e-06 25.0 0.0 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 EAQ89644.1 - 0.00034 20.4 0.2 0.00075 19.3 0.2 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EAQ89644.1 - 0.0018 18.7 0.1 0.25 11.7 0.1 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.6 EAQ89644.1 - 0.0022 18.4 0.7 0.0073 16.7 0.1 2.0 2 0 0 2 2 2 1 AAA domain CbiA PF01656.23 EAQ89644.1 - 0.006 16.6 1.2 2.1 8.4 0.1 3.1 3 0 0 3 3 3 1 CobQ/CobB/MinD/ParA nucleotide binding domain cobW PF02492.19 EAQ89644.1 - 0.043 13.4 0.1 0.084 12.5 0.1 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain SMC_N PF02463.19 EAQ89644.1 - 0.048 13.1 0.0 0.079 12.4 0.0 1.3 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain ABC_tran PF00005.27 EAQ89644.1 - 0.061 13.8 0.0 0.26 11.8 0.0 2.0 2 0 0 2 2 2 0 ABC transporter MMR_HSR1 PF01926.23 EAQ89644.1 - 0.067 13.3 0.1 0.24 11.5 0.1 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_33 PF13671.6 EAQ89644.1 - 0.096 12.8 0.0 0.24 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EAQ89644.1 - 0.13 12.0 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain PI3_PI4_kinase PF00454.27 EAQ89645.1 - 1.6e-49 169.0 0.0 3.3e-49 168.0 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 EAQ89645.1 - 3.7e-35 121.7 0.4 6.6e-35 120.9 0.4 1.4 1 0 0 1 1 1 1 FAT domain UME PF08064.13 EAQ89645.1 - 1.2e-32 111.8 2.1 3.3e-32 110.4 0.5 2.8 2 1 0 2 2 2 1 UME (NUC010) domain zf-PARP PF00645.18 EAQ89645.1 - 3.9e-23 82.1 1.1 1.2e-22 80.6 1.1 1.9 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region IFRD PF05004.13 EAQ89645.1 - 0.015 14.4 0.5 3.2 6.8 0.0 3.4 3 0 0 3 3 3 0 Interferon-related developmental regulator (IFRD) Med17 PF10156.9 EAQ89647.1 - 7.1e-80 269.0 0.0 2e-79 267.5 0.0 1.6 2 0 0 2 2 2 1 Subunit 17 of Mediator complex Spt20 PF12090.8 EAQ89647.1 - 5.7 6.5 9.7 1.4 8.5 6.0 1.7 2 0 0 2 2 2 0 Spt20 family PFK PF00365.20 EAQ89648.1 - 9.4e-175 579.7 0.6 1.4e-104 349.4 0.9 2.2 2 0 0 2 2 2 2 Phosphofructokinase UVR PF02151.19 EAQ89648.1 - 0.0045 16.7 0.2 0.014 15.1 0.2 1.8 1 0 0 1 1 1 1 UvrB/uvrC motif DAGK_cat PF00781.24 EAQ89648.1 - 0.12 12.0 0.0 0.65 9.6 0.1 2.3 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain Podoplanin PF05808.11 EAQ89649.1 - 0.0011 19.1 0.1 0.0022 18.1 0.1 1.5 1 0 0 1 1 1 1 Podoplanin SKG6 PF08693.10 EAQ89649.1 - 0.014 14.8 3.8 0.028 13.8 3.8 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain PrgU PF09627.10 EAQ89649.1 - 0.12 12.3 0.9 3.5 7.6 0.0 2.5 2 0 0 2 2 2 0 PrgU-like protein SNF2_N PF00176.23 EAQ89650.1 - 3.1e-51 174.2 1.9 1.8e-36 125.6 0.1 2.4 1 1 1 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 EAQ89650.1 - 1.6e-16 60.6 0.1 3.5e-16 59.5 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.6 EAQ89650.1 - 2.9e-08 33.5 2.0 5.4e-08 32.6 2.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EAQ89650.1 - 2.5e-07 30.6 1.4 3.9e-07 30.0 0.5 1.9 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EAQ89650.1 - 6.2e-07 29.1 1.5 6.2e-07 29.1 1.5 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EAQ89650.1 - 1.8e-06 28.2 4.2 3.7e-06 27.2 4.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EAQ89650.1 - 2.9e-06 27.1 4.0 5.2e-06 26.2 4.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EAQ89650.1 - 4e-05 23.5 3.1 7.5e-05 22.6 3.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 EAQ89650.1 - 0.00031 20.8 3.9 0.00071 19.7 3.9 1.7 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING AF-4 PF05110.13 EAQ89650.1 - 0.0023 16.1 0.7 0.0038 15.4 0.7 1.2 1 0 0 1 1 1 1 AF-4 proto-oncoprotein ResIII PF04851.15 EAQ89650.1 - 0.0023 17.9 0.8 0.005 16.9 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-RING_4 PF14570.6 EAQ89650.1 - 0.12 12.2 5.2 0.57 10.0 5.5 2.0 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 EAQ89650.1 - 0.12 12.2 7.3 1.3 9.0 7.6 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-MIZ PF02891.20 EAQ89650.1 - 0.16 11.8 1.2 0.34 10.7 1.2 1.6 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger DZR PF12773.7 EAQ89650.1 - 2.8 8.0 7.0 0.76 9.8 3.8 1.7 2 0 0 2 2 1 0 Double zinc ribbon Phosphodiest PF01663.22 EAQ89651.1 - 5.3e-95 319.0 0.5 7.3e-95 318.6 0.5 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 EAQ89651.1 - 0.0023 17.4 0.0 0.069 12.5 0.0 2.2 2 0 0 2 2 2 1 Sulfatase PglZ PF08665.12 EAQ89651.1 - 0.071 13.2 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 PglZ domain DUF2063 PF09836.9 EAQ89651.1 - 0.15 12.3 0.0 0.32 11.3 0.0 1.4 1 0 0 1 1 1 0 Putative DNA-binding domain YwiC PF14256.6 EAQ89651.1 - 0.18 12.1 0.2 0.29 11.5 0.2 1.2 1 0 0 1 1 1 0 YwiC-like protein Acetyltransf_1 PF00583.25 EAQ89652.1 - 0.00083 19.6 0.0 0.011 16.0 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EAQ89652.1 - 0.006 17.0 0.0 0.011 16.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EAQ89652.1 - 0.023 14.6 0.0 0.044 13.7 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 EAQ89652.1 - 0.096 12.7 0.0 0.25 11.3 0.0 1.7 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Acetyltransf_15 PF17013.5 EAQ89652.1 - 0.22 11.0 0.0 0.3 10.5 0.0 1.1 1 0 0 1 1 1 0 Putative acetyl-transferase Ribosomal_L14e PF01929.17 EAQ89653.1 - 6.3e-33 113.1 2.1 9.4e-33 112.5 2.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L14 NAC PF01849.18 EAQ89654.1 - 2.1e-23 82.0 0.1 3.2e-23 81.5 0.1 1.3 1 0 0 1 1 1 1 NAC domain Myc_N PF01056.18 EAQ89654.1 - 0.19 11.6 8.1 0.3 11.0 8.1 1.3 1 1 0 1 1 1 0 Myc amino-terminal region FYDLN_acid PF09538.10 EAQ89654.1 - 5.7 7.7 14.7 0.56 10.9 5.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Mt_ATP-synt_D PF05873.12 EAQ89655.1 - 1e-22 80.6 1.9 1.3e-22 80.4 1.9 1.0 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) T5orf172 PF10544.9 EAQ89655.1 - 0.03 14.9 0.0 0.053 14.1 0.0 1.4 1 0 0 1 1 1 0 T5orf172 domain Dor1 PF04124.12 EAQ89655.1 - 0.047 12.4 2.0 0.057 12.1 2.0 1.1 1 0 0 1 1 1 0 Dor1-like family Helo_like_N PF17111.5 EAQ89655.1 - 0.074 12.4 1.5 0.17 11.3 1.5 1.6 1 1 0 1 1 1 0 Fungal N-terminal domain of STAND proteins DUF2408 PF10303.9 EAQ89655.1 - 0.14 12.8 1.7 0.18 12.4 1.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) CLIP_SPH_Scar PF18399.1 EAQ89656.1 - 0.0023 18.0 0.0 0.0062 16.6 0.0 1.7 1 0 0 1 1 1 1 Clip-domain serine protease homolog Scarface COX16 PF14138.6 EAQ89657.1 - 4.1e-31 107.3 0.0 4.6e-31 107.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 Amidohydro_1 PF01979.20 EAQ89660.1 - 7.8e-14 51.7 1.0 9.3e-13 48.2 1.0 2.0 1 1 0 1 1 1 1 Amidohydrolase family DUF1687 PF07955.11 EAQ89662.1 - 7.8e-32 110.4 0.0 1e-31 110.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1687) Adeno_PV PF03910.13 EAQ89662.1 - 0.034 12.8 2.2 0.047 12.4 2.2 1.1 1 0 0 1 1 1 0 Adenovirus minor core protein PV YfbU PF03887.14 EAQ89664.1 - 0.024 14.6 0.4 0.04 13.9 0.4 1.5 1 0 0 1 1 1 0 YfbU domain Sel1 PF08238.12 EAQ89665.1 - 1.8e-44 149.1 21.9 2.8e-07 31.0 0.0 7.7 7 0 0 7 7 7 7 Sel1 repeat CBP4 PF07960.11 EAQ89666.1 - 6.4e-29 100.4 1.0 7.3e-29 100.3 1.0 1.0 1 0 0 1 1 1 1 CBP4 DUF2852 PF11014.8 EAQ89666.1 - 2.8 8.1 6.7 1.1 9.4 4.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2852) NAC PF01849.18 EAQ89667.1 - 2.7e-24 84.9 0.4 1e-23 83.0 0.2 1.9 2 0 0 2 2 2 1 NAC domain A_deamin PF02137.18 EAQ89668.1 - 2.5e-20 73.2 0.0 1.1e-19 71.1 0.0 2.0 1 1 0 1 1 1 1 Adenosine-deaminase (editase) domain Mito_fiss_reg PF05308.11 EAQ89668.1 - 5.9 6.9 6.5 9.8 6.2 6.5 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator Ribosomal_L24e PF01246.20 EAQ89669.1 - 5.8e-29 100.1 0.1 1.3e-28 99.0 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein L24e Redoxin PF08534.10 EAQ89670.1 - 2.3e-38 131.2 0.0 2.5e-38 131.1 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 EAQ89670.1 - 2.2e-07 30.8 0.0 2.9e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family DUF1348 PF07080.11 EAQ89671.1 - 9.3e-20 70.9 0.1 1.2e-19 70.6 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) SnoaL_2 PF12680.7 EAQ89671.1 - 0.085 13.5 0.0 0.11 13.2 0.0 1.2 1 0 0 1 1 1 0 SnoaL-like domain Pkinase PF00069.25 EAQ89672.1 - 9.5e-05 21.9 0.0 0.00011 21.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ89672.1 - 0.0075 15.6 0.0 0.0082 15.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RGS PF00615.19 EAQ89673.1 - 0.00031 21.0 0.0 0.067 13.5 0.0 2.2 2 0 0 2 2 2 2 Regulator of G protein signaling domain Fumble PF03630.14 EAQ89674.1 - 6.5e-145 482.4 0.0 7.9e-145 482.1 0.0 1.1 1 0 0 1 1 1 1 Fumble MPC PF03650.13 EAQ89675.1 - 3.3e-47 159.2 1.3 4.3e-47 158.8 1.3 1.1 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers Abhydrolase_6 PF12697.7 EAQ89677.1 - 1.8e-07 32.0 0.1 3.9e-07 30.9 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EAQ89677.1 - 5e-05 23.1 0.0 0.00012 21.8 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold BAAT_C PF08840.11 EAQ89677.1 - 0.17 11.8 0.0 6.8 6.5 0.0 2.3 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal RNase_PH PF01138.21 EAQ89678.1 - 5.7e-09 36.6 0.0 7.4e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 EAQ89678.1 - 0.019 15.0 0.0 0.029 14.4 0.0 1.3 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 GDI PF00996.18 EAQ89679.1 - 4.7e-26 91.3 0.0 8.6e-26 90.4 0.0 1.3 1 1 0 1 1 1 1 GDP dissociation inhibitor Rad21_Rec8 PF04824.16 EAQ89680.1 - 7.3e-09 34.8 0.0 2e-08 33.4 0.0 1.7 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein Rad21_Rec8_N PF04825.13 EAQ89680.1 - 5.5e-05 23.3 0.1 0.0035 17.5 0.1 2.2 1 1 1 2 2 2 2 N terminus of Rad21 / Rec8 like protein ALO PF04030.14 EAQ89681.1 - 8.6e-99 330.6 0.4 1e-98 330.3 0.4 1.1 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 EAQ89681.1 - 8.2e-28 96.9 0.2 1.2e-27 96.3 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain BTB PF00651.31 EAQ89682.1 - 3.2e-27 95.0 0.0 3.7e-13 49.7 0.2 3.1 3 0 0 3 3 3 2 BTB/POZ domain Ank_4 PF13637.6 EAQ89682.1 - 2.1e-07 31.4 0.0 5.1e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAQ89682.1 - 5.2e-07 30.2 0.0 1.3e-06 28.9 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EAQ89682.1 - 2.2e-06 27.8 0.1 0.016 15.7 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 EAQ89682.1 - 8.4e-06 26.0 0.0 2.5e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAQ89682.1 - 0.00015 22.0 0.1 0.14 12.8 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat DUF4904 PF16247.5 EAQ89683.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4904) Pkinase PF00069.25 EAQ89684.1 - 7.7e-55 186.1 0.1 1.1e-34 120.1 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ89684.1 - 3.7e-36 124.7 0.0 5.4e-26 91.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 EAQ89684.1 - 0.00044 19.1 0.7 0.2 10.4 0.0 2.5 2 0 0 2 2 2 2 Fungal protein kinase Kinase-like PF14531.6 EAQ89684.1 - 0.0099 15.2 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like ATP-synt_D PF01813.17 EAQ89684.1 - 0.012 15.4 1.8 0.024 14.5 1.8 1.4 1 0 0 1 1 1 0 ATP synthase subunit D DUF3896 PF13035.6 EAQ89684.1 - 0.075 13.2 0.5 0.22 11.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3896) APH PF01636.23 EAQ89684.1 - 0.12 12.2 0.0 0.36 10.7 0.0 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family DUF4164 PF13747.6 EAQ89684.1 - 0.48 10.7 7.3 1.2 9.4 7.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) zf-C2H2 PF00096.26 EAQ89687.1 - 2.1e-09 37.3 10.3 0.00024 21.4 1.8 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EAQ89687.1 - 5.3e-06 26.6 11.0 2.3e-05 24.6 1.5 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 EAQ89687.1 - 2.9e-05 24.5 9.9 0.028 15.2 1.6 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 EAQ89687.1 - 0.023 14.7 0.5 0.023 14.7 0.5 2.0 2 0 0 2 2 2 0 C2H2-type zinc finger Spt20 PF12090.8 EAQ89687.1 - 0.12 12.0 5.7 0.22 11.1 5.7 1.4 1 0 0 1 1 1 0 Spt20 family zf-met PF12874.7 EAQ89687.1 - 0.16 12.4 2.3 0.61 10.6 0.8 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EAQ89687.1 - 0.19 12.0 2.9 0.47 10.8 0.1 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Zn_ribbon_SprT PF17283.2 EAQ89687.1 - 0.57 10.1 6.3 0.36 10.8 0.9 2.3 2 0 0 2 2 2 0 SprT-like zinc ribbon domain Lipase_GDSL_2 PF13472.6 EAQ89688.1 - 4.7e-11 43.4 1.6 1e-10 42.3 1.6 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EAQ89688.1 - 9.3e-10 38.8 1.0 1.9e-09 37.8 1.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 EAQ89688.1 - 0.24 11.5 0.4 4.4 7.4 0.0 2.2 1 1 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family BORCS6 PF10157.9 EAQ89689.1 - 0.03 14.6 1.1 0.044 14.0 0.5 1.7 1 1 0 1 1 1 0 BLOC-1-related complex sub-unit 6 SMP_2 PF10144.9 EAQ89689.1 - 0.07 12.8 0.1 0.1 12.2 0.1 1.3 1 0 0 1 1 1 0 Bacterial virulence factor haemolysin GAPES4 PF17157.4 EAQ89689.1 - 0.1 13.0 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 Gammaproteobacterial periplasmic sensor domain Rnk_N PF14760.6 EAQ89689.1 - 0.31 11.6 8.3 1.1 9.8 3.8 3.0 2 2 0 2 2 2 0 Rnk N-terminus PHD PF00628.29 EAQ89690.1 - 4.9e-12 45.6 7.5 4.9e-12 45.6 7.5 2.1 3 0 0 3 3 3 1 PHD-finger PHD_2 PF13831.6 EAQ89690.1 - 0.063 12.8 2.0 0.17 11.4 2.0 1.8 1 0 0 1 1 1 0 PHD-finger PHD_3 PF13922.6 EAQ89690.1 - 0.082 13.3 0.7 0.082 13.3 0.7 2.2 2 0 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx SCO1-SenC PF02630.14 EAQ89691.1 - 2e-43 147.5 0.0 3e-43 146.9 0.0 1.2 1 0 0 1 1 1 1 SCO1/SenC Thioredoxin_8 PF13905.6 EAQ89691.1 - 0.007 16.7 0.0 0.013 15.8 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Choline_kinase PF01633.20 EAQ89692.1 - 1.3e-30 106.6 0.0 4.4e-30 104.9 0.0 1.9 1 1 0 1 1 1 1 Choline/ethanolamine kinase Choline_kin_N PF04428.14 EAQ89692.1 - 2.9e-23 81.3 0.0 5.4e-23 80.4 0.0 1.5 1 0 0 1 1 1 1 Choline kinase N terminus DUF2937 PF11157.8 EAQ89692.1 - 0.17 11.6 0.0 0.5 10.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) DUF3433 PF11915.8 EAQ89694.1 - 1.4e-19 70.3 17.5 8.4e-17 61.4 3.3 3.5 4 0 0 4 4 4 2 Protein of unknown function (DUF3433) Transgly_assoc PF04226.13 EAQ89694.1 - 0.076 13.3 2.5 0.34 11.2 1.7 2.5 1 1 1 2 2 2 0 Transglycosylase associated protein DUF3565 PF12088.8 EAQ89696.1 - 0.1 12.5 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3565) Hydrolase_6 PF13344.6 EAQ89698.1 - 8.7e-27 93.2 0.0 1.2e-26 92.7 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EAQ89698.1 - 0.0023 18.2 0.0 4.4 7.5 0.0 3.2 1 1 2 3 3 3 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EAQ89698.1 - 0.012 15.7 0.1 0.028 14.5 0.1 1.6 1 0 0 1 1 1 0 HAD-hyrolase-like OPT PF03169.15 EAQ89699.1 - 1.4e-185 618.5 56.4 1.7e-185 618.3 56.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein MoaE PF02391.17 EAQ89700.1 - 7.3e-23 81.0 0.0 9.8e-23 80.6 0.0 1.1 1 0 0 1 1 1 1 MoaE protein G-patch PF01585.23 EAQ89701.1 - 3.3e-11 42.9 2.3 6.5e-11 41.9 2.3 1.5 1 0 0 1 1 1 1 G-patch domain RRM_1 PF00076.22 EAQ89701.1 - 2.2e-07 30.6 0.9 0.00082 19.1 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RanBP PF00641.18 EAQ89701.1 - 2.7e-05 23.4 0.1 5.6e-05 22.4 0.1 1.6 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others G-patch_2 PF12656.7 EAQ89701.1 - 0.0023 18.0 6.6 0.0038 17.3 4.6 2.2 2 0 0 2 2 2 1 G-patch domain RED_N PF07808.13 EAQ89701.1 - 0.008 15.8 2.0 0.012 15.2 0.9 1.7 2 0 0 2 2 2 1 RED-like protein N-terminal region T3SS_needle_E PF08988.10 EAQ89702.1 - 0.047 13.8 0.1 0.19 11.9 0.0 2.0 2 0 0 2 2 2 0 Type III secretion system, cytoplasmic E component of needle Asp PF00026.23 EAQ89703.1 - 2.6e-48 165.1 0.1 2.9e-37 128.8 0.1 3.0 2 1 1 3 3 3 3 Eukaryotic aspartyl protease TAXi_N PF14543.6 EAQ89703.1 - 2e-10 41.2 0.1 5.4e-10 39.8 0.1 1.8 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EAQ89703.1 - 0.00046 20.8 0.6 0.47 11.1 0.1 2.7 2 0 0 2 2 2 2 Aspartyl protease HATPase_c PF02518.26 EAQ89704.1 - 5.7e-23 81.6 0.0 1.4e-22 80.3 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_9 PF13426.7 EAQ89704.1 - 7.2e-15 55.1 0.0 1.6e-05 25.1 0.0 4.1 4 1 0 4 4 4 3 PAS domain PAS_4 PF08448.10 EAQ89704.1 - 1.8e-09 37.8 0.0 0.0022 18.2 0.0 5.4 5 0 0 5 5 5 1 PAS fold HisKA PF00512.25 EAQ89704.1 - 2.1e-09 37.3 0.0 2.5e-08 33.8 0.0 3.0 3 1 0 3 3 3 1 His Kinase A (phospho-acceptor) domain PAS PF00989.25 EAQ89704.1 - 4.7e-09 36.3 0.0 0.0018 18.2 0.0 3.1 2 0 0 2 2 2 2 PAS fold Response_reg PF00072.24 EAQ89704.1 - 7.1e-09 35.8 0.4 2.8e-08 33.9 0.0 2.1 2 0 0 2 2 2 1 Response regulator receiver domain PAS_3 PF08447.12 EAQ89704.1 - 2.8e-07 30.7 0.0 0.013 15.8 0.0 3.5 2 1 0 2 2 2 2 PAS fold PAS_8 PF13188.7 EAQ89704.1 - 5.3e-07 29.5 0.0 0.0015 18.5 0.0 3.9 3 0 0 3 3 3 1 PAS domain GAF_3 PF13492.6 EAQ89704.1 - 0.013 15.8 0.0 0.035 14.5 0.0 1.7 1 0 0 1 1 1 0 GAF domain APOBEC4_like PF18774.1 EAQ89704.1 - 0.21 11.5 0.4 16 5.4 0.0 3.0 2 1 1 3 3 3 0 APOBEC4-like -AID/APOBEC-deaminase Polyketide_cyc2 PF10604.9 EAQ89705.1 - 0.002 18.4 2.5 0.38 11.0 2.5 2.7 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Peroxin-13_N PF04088.13 EAQ89708.1 - 0.15 12.4 0.7 1.1 9.6 0.0 2.4 2 1 0 2 2 2 0 Peroxin 13, N-terminal region CRA PF06589.11 EAQ89708.1 - 0.36 10.9 6.8 0.67 10.1 6.8 1.4 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) SecE PF00584.20 EAQ89708.1 - 0.67 9.9 2.6 0.45 10.5 0.6 1.7 2 0 0 2 2 2 0 SecE/Sec61-gamma subunits of protein translocation complex Menin PF05053.13 EAQ89708.1 - 1.3 7.2 7.1 2.1 6.6 7.1 1.3 1 0 0 1 1 1 0 Menin Methyltransf_2 PF00891.18 EAQ89709.1 - 1.2e-24 86.8 0.0 2.1e-24 86.0 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_25 PF13649.6 EAQ89709.1 - 0.0027 18.4 0.0 0.019 15.7 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.7 EAQ89709.1 - 0.033 14.1 0.0 0.061 13.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain CheR PF01739.18 EAQ89709.1 - 0.1 12.1 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Methyltransf_23 PF13489.6 EAQ89710.1 - 7.3e-10 38.9 0.0 1.9e-08 34.4 0.0 2.2 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAQ89710.1 - 0.00032 21.3 0.0 0.00081 20.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EAQ89710.1 - 0.0082 15.6 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.17 EAQ89710.1 - 0.048 13.1 0.0 0.081 12.4 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_31 PF13847.6 EAQ89710.1 - 0.098 12.5 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 EAQ89710.1 - 0.16 12.6 0.0 0.34 11.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 EAQ89710.1 - 0.16 12.7 0.1 0.65 10.8 0.1 2.0 1 1 1 2 2 2 0 Methyltransferase domain PCI PF01399.27 EAQ89711.1 - 6.8e-21 74.8 0.0 2.5e-20 72.9 0.0 2.0 1 0 0 1 1 1 1 PCI domain RPN5_C PF18098.1 EAQ89711.1 - 2.8e-16 59.3 0.9 7.1e-16 58.0 0.9 1.8 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain NFACT-C PF11923.8 EAQ89712.1 - 2.2e-38 130.4 0.7 2.2e-38 130.4 0.7 2.6 2 0 0 2 2 2 1 NFACT protein C-terminal domain NFACT-R_1 PF05670.13 EAQ89712.1 - 5.9e-33 113.8 0.0 1.7e-32 112.3 0.0 1.9 1 0 0 1 1 1 1 NFACT protein RNA binding domain FbpA PF05833.11 EAQ89712.1 - 3.1e-30 105.3 9.2 3.1e-30 105.3 9.2 2.1 2 1 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) PDE6_gamma PF04868.12 EAQ89712.1 - 1.5 9.1 3.8 5.4 7.3 3.2 2.2 2 0 0 2 2 2 0 Retinal cGMP phosphodiesterase, gamma subunit GREB1 PF15782.5 EAQ89712.1 - 6.4 3.7 13.8 9.8 3.1 13.8 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer eIF-5a PF01287.20 EAQ89713.1 - 3.3e-08 33.5 0.1 5.3e-08 32.9 0.1 1.3 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold LRRC37 PF15779.5 EAQ89717.1 - 0.86 10.0 4.8 1.6 9.1 4.8 1.5 1 1 0 1 1 1 0 Leucine-rich repeat-containing protein 37 family S1-P1_nuclease PF02265.16 EAQ89719.1 - 2.8e-73 246.9 0.0 3.7e-73 246.5 0.0 1.2 1 0 0 1 1 1 1 S1/P1 Nuclease HTH_33 PF13592.6 EAQ89719.1 - 0.056 13.1 0.6 0.27 10.9 0.0 2.3 3 0 0 3 3 3 0 Winged helix-turn helix PQ-loop PF04193.14 EAQ89720.1 - 7.5e-20 70.5 2.0 2e-15 56.3 0.0 2.7 3 0 0 3 3 3 2 PQ loop repeat F-box-like PF12937.7 EAQ89721.1 - 8.4e-06 25.6 0.0 1.9e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 EAQ89721.1 - 0.12 12.9 5.0 5 7.7 0.1 4.2 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) UPF0139 PF03669.13 EAQ89722.1 - 6.1e-07 29.2 0.0 1.2e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) HTH_32 PF13565.6 EAQ89722.1 - 0.00055 20.5 1.4 0.13 12.9 0.0 3.6 3 1 1 4 4 4 1 Homeodomain-like domain HTH_23 PF13384.6 EAQ89722.1 - 0.0084 15.9 0.4 0.024 14.5 0.0 2.0 2 0 0 2 2 2 1 Homeodomain-like domain Med12 PF09497.10 EAQ89723.1 - 3.7e-29 100.8 0.4 7.4e-29 99.8 0.4 1.6 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 Med12-LCEWAV PF12145.8 EAQ89723.1 - 0.014 14.3 0.0 0.029 13.3 0.0 1.4 1 1 0 1 1 1 0 Eukaryotic Mediator 12 subunit domain HET PF06985.11 EAQ89724.1 - 2.6e-25 89.5 0.0 7.4e-25 88.0 0.0 1.8 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Trypan_PARP PF05887.11 EAQ89724.1 - 0.032 14.2 18.3 3.5 7.6 15.7 2.4 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) MafB19-deam PF14437.6 EAQ89724.1 - 0.14 11.9 0.1 0.28 10.9 0.1 1.4 1 0 0 1 1 1 0 MafB19-like deaminase FAD_binding_4 PF01565.23 EAQ89725.1 - 7.5e-13 48.4 2.9 1.1e-12 47.9 2.9 1.3 1 0 0 1 1 1 1 FAD binding domain ALO PF04030.14 EAQ89725.1 - 0.094 12.5 0.1 0.18 11.6 0.1 1.4 1 0 0 1 1 1 0 D-arabinono-1,4-lactone oxidase APH PF01636.23 EAQ89726.1 - 1.5e-10 41.5 0.0 2.7e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 EAQ89726.1 - 0.0012 18.3 0.0 0.0023 17.3 0.0 1.4 1 0 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.11 EAQ89726.1 - 0.003 16.5 0.0 0.0044 16.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) Phage_TAC_12 PF12363.8 EAQ89726.1 - 0.02 15.3 0.0 0.036 14.5 0.0 1.4 1 0 0 1 1 1 0 Phage tail assembly chaperone protein, TAC Choline_kinase PF01633.20 EAQ89726.1 - 0.041 13.5 0.0 0.064 12.8 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Alpha_kinase PF02816.18 EAQ89727.1 - 2.1e-48 164.9 0.0 2.6e-48 164.6 0.0 1.1 1 0 0 1 1 1 1 Alpha-kinase family BTB PF00651.31 EAQ89728.1 - 2.6e-12 46.9 0.0 5.6e-12 45.9 0.0 1.6 1 1 0 1 1 1 1 BTB/POZ domain Nucleoporin_FG PF13634.6 EAQ89728.1 - 0.03 15.2 5.7 0.084 13.7 5.7 1.7 1 0 0 1 1 1 0 Nucleoporin FG repeat region WSC PF01822.19 EAQ89729.1 - 1.2e-26 92.7 9.2 9e-23 80.3 1.4 4.1 3 1 1 4 4 4 3 WSC domain RabGAP-TBC PF00566.18 EAQ89730.1 - 1.5e-45 155.5 0.0 2.2e-45 154.9 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_6 PF13405.6 EAQ89730.1 - 2.8e-05 23.7 0.2 0.0074 16.1 0.2 3.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 EAQ89730.1 - 0.0026 18.2 0.1 0.05 14.1 0.3 2.8 1 1 2 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 EAQ89730.1 - 0.0069 15.9 0.4 0.66 9.7 0.4 3.3 3 0 0 3 3 3 1 EF hand DUF4611 PF15387.6 EAQ89730.1 - 0.61 10.4 14.5 1.9 8.8 3.5 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF4611) Pkinase PF00069.25 EAQ89731.1 - 1.8e-46 158.7 0.0 2.4e-46 158.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ89731.1 - 4.1e-19 68.9 0.0 5.5e-19 68.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EAQ89731.1 - 0.0091 14.8 0.0 0.018 13.8 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EAQ89731.1 - 0.039 13.9 4.9 0.087 12.7 0.1 2.5 2 1 1 3 3 3 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EAQ89731.1 - 0.056 12.5 0.0 0.086 11.9 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Med3 PF11593.8 EAQ89731.1 - 0.71 9.0 4.0 1 8.5 4.0 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Exo_endo_phos PF03372.23 EAQ89732.1 - 0.00023 20.8 0.0 0.59 9.6 0.0 2.3 2 0 0 2 2 2 2 Endonuclease/Exonuclease/phosphatase family Pkinase PF00069.25 EAQ89733.1 - 3.5e-06 26.6 0.0 0.0013 18.1 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_fungal PF17667.1 EAQ89733.1 - 0.0044 15.9 0.0 0.007 15.2 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase DEADboxA PF12343.8 EAQ89733.1 - 0.089 13.3 0.9 0.27 11.8 0.9 1.8 1 0 0 1 1 1 0 Cold shock protein DEAD box A Pal1 PF08316.11 EAQ89735.1 - 4.6e-47 160.2 0.2 4.6e-47 160.2 0.2 1.9 2 0 0 2 2 2 1 Pal1 cell morphology protein DUF3915 PF13054.6 EAQ89735.1 - 0.91 9.5 4.1 1.8 8.5 4.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Fasciclin PF02469.22 EAQ89736.1 - 3.2e-06 27.4 0.2 5.2e-06 26.7 0.2 1.3 1 0 0 1 1 1 1 Fasciclin domain LysM PF01476.20 EAQ89738.1 - 0.065 13.3 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 LysM domain zf-C3Hc3H PF13891.6 EAQ89738.1 - 0.32 11.4 3.3 4 7.9 0.0 2.7 3 1 1 4 4 4 0 Potential DNA-binding domain PIF1 PF05970.14 EAQ89739.1 - 3.1e-11 43.0 0.0 0.00011 21.5 0.0 2.2 2 0 0 2 2 2 2 PIF1-like helicase UvrD_C_2 PF13538.6 EAQ89739.1 - 0.0024 17.6 0.1 0.0098 15.7 0.1 2.0 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.14 EAQ89739.1 - 0.019 12.9 0.0 0.027 12.4 0.0 1.1 1 0 0 1 1 1 0 Helicase Glyco_hydro_18 PF00704.28 EAQ89741.1 - 3.5e-32 112.4 1.2 5.9e-32 111.6 1.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 EAQ89741.1 - 1.6e-05 25.3 8.2 1.6e-05 25.3 8.2 3.3 3 0 0 3 3 3 1 Chitin recognition protein LysM PF01476.20 EAQ89741.1 - 0.00025 21.1 0.0 0.0033 17.4 0.1 2.3 2 0 0 2 2 2 1 LysM domain zf-C2H2 PF00096.26 EAQ89743.1 - 0.001 19.4 21.4 0.0088 16.5 0.9 3.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type Adeno_E3_CR2 PF02439.15 EAQ89743.1 - 0.026 14.3 0.3 0.048 13.4 0.3 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 zf-C2H2_4 PF13894.6 EAQ89743.1 - 0.17 12.8 19.0 0.5 11.3 3.0 3.8 3 0 0 3 3 3 0 C2H2-type zinc finger FOXP-CC PF16159.5 EAQ89743.1 - 0.85 10.3 3.1 4.4 8.0 0.8 2.5 1 1 1 2 2 2 0 FOXP coiled-coil domain Rrp40_N PF18311.1 EAQ89744.1 - 6.3e-21 74.0 1.0 7.9e-21 73.7 1.0 1.1 1 0 0 1 1 1 1 Exosome complex exonuclease Rrp40 N-terminal domain HSP70 PF00012.20 EAQ89745.1 - 2.2e-77 260.6 1.5 2.2e-77 260.6 1.5 1.9 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 EAQ89745.1 - 2.6e-07 29.8 0.3 4.7e-07 28.9 0.3 1.4 1 0 0 1 1 1 1 MreB/Mbl protein Raco_middle PF17651.1 EAQ89745.1 - 0.12 12.0 0.0 0.9 9.2 0.0 2.2 2 0 0 2 2 2 0 RACo middle region DUF3221 PF11518.8 EAQ89745.1 - 0.15 12.4 3.5 0.41 11.0 2.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3221) FAM176 PF14851.6 EAQ89745.1 - 0.52 10.0 2.6 1.1 8.9 2.6 1.5 1 0 0 1 1 1 0 FAM176 family DNA_pol_phi PF04931.13 EAQ89745.1 - 7.7 4.5 8.4 12 3.9 8.4 1.2 1 0 0 1 1 1 0 DNA polymerase phi Prok-RING_4 PF14447.6 EAQ89746.1 - 0.012 15.4 0.4 0.012 15.4 0.4 2.7 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 EAQ89746.1 - 0.029 14.2 0.1 0.029 14.2 0.1 3.1 4 0 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EAQ89746.1 - 0.34 11.0 0.0 0.34 11.0 0.0 3.1 3 0 0 3 3 3 0 RING-type zinc-finger Nucleo_P87 PF07267.11 EAQ89746.1 - 1.3 7.8 6.5 1.8 7.3 6.5 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 NOA36 PF06524.12 EAQ89746.1 - 2 7.7 8.7 4.7 6.5 8.7 1.6 1 0 0 1 1 1 0 NOA36 protein FAM176 PF14851.6 EAQ89746.1 - 2.2 8.0 4.9 5.3 6.7 4.9 1.6 1 0 0 1 1 1 0 FAM176 family Nop14 PF04147.12 EAQ89746.1 - 3.3 5.8 10.3 4.5 5.4 10.3 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 EAQ89746.1 - 6.6 4.9 7.5 8.8 4.5 7.5 1.1 1 0 0 1 1 1 0 CDC45-like protein zf-C3HC4 PF00097.25 EAQ89747.1 - 0.0014 18.5 0.1 0.0014 18.5 0.1 2.2 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EAQ89747.1 - 0.0019 18.0 0.4 0.0019 18.0 0.4 2.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EAQ89747.1 - 0.0064 16.5 1.4 0.0064 16.5 1.4 2.4 2 0 0 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 EAQ89747.1 - 0.012 15.4 0.4 0.012 15.4 0.4 2.7 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 EAQ89747.1 - 0.016 15.4 0.1 0.016 15.4 0.1 2.4 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING RNA_pol_Rpc4 PF05132.14 EAQ89747.1 - 0.035 14.5 0.7 0.16 12.4 0.0 2.0 2 0 0 2 2 2 0 RNA polymerase III RPC4 zf-C3HC4_3 PF13920.6 EAQ89747.1 - 0.046 13.6 0.5 0.046 13.6 0.5 2.9 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EAQ89747.1 - 0.35 10.8 9.5 0.097 12.6 2.9 2.6 2 1 0 2 2 2 0 zinc-RING finger domain Zip PF02535.22 EAQ89747.1 - 0.88 8.7 5.9 0.33 10.1 3.1 1.7 2 0 0 2 2 2 0 ZIP Zinc transporter SelP_N PF04592.14 EAQ89747.1 - 1.1 8.6 6.4 1.9 7.9 6.4 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region POP1 PF06978.11 EAQ89749.1 - 4.6e-77 258.6 15.5 9e-77 257.7 15.5 1.5 1 0 0 1 1 1 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.12 EAQ89749.1 - 2.9e-30 104.4 0.1 7.6e-30 103.1 0.1 1.7 1 0 0 1 1 1 1 POPLD (NUC188) domain IBR PF01485.21 EAQ89750.1 - 2.2e-12 47.0 24.5 1.6e-06 28.3 8.0 3.4 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain zf-RING_UBOX PF13445.6 EAQ89750.1 - 0.00057 19.9 1.3 0.00057 19.9 1.3 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EAQ89750.1 - 0.014 15.3 1.6 0.014 15.3 1.6 3.4 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EAQ89750.1 - 0.08 12.8 0.2 0.08 12.8 0.2 3.6 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Spt20 PF12090.8 EAQ89750.1 - 0.66 9.5 18.1 1.1 8.8 18.1 1.3 1 0 0 1 1 1 0 Spt20 family CCDC53 PF10152.9 EAQ89750.1 - 2 8.8 19.3 0.8 10.1 10.6 2.6 3 0 0 3 3 3 0 Subunit CCDC53 of WASH complex SH3_1 PF00018.28 EAQ89751.1 - 7.4e-14 51.1 0.0 1.1e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EAQ89751.1 - 1.4e-09 37.7 0.1 2.5e-09 36.9 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EAQ89751.1 - 1.4e-07 31.1 0.0 2.4e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Spt20 PF12090.8 EAQ89751.1 - 4.7 6.8 8.1 6.4 6.3 8.1 1.1 1 0 0 1 1 1 0 Spt20 family CNH PF00780.22 EAQ89752.1 - 1.1e-77 261.4 0.0 4.9e-77 259.2 0.0 1.9 2 0 0 2 2 2 1 CNH domain PH_5 PF15405.6 EAQ89752.1 - 5.5e-42 143.1 0.0 1.4e-41 141.8 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.20 EAQ89752.1 - 3.4e-34 118.7 0.0 6.8e-34 117.7 0.0 1.5 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.21 EAQ89752.1 - 1.6e-15 56.9 0.1 3e-15 56.0 0.1 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) ATP-synt_C PF00137.21 EAQ89753.1 - 6.4e-28 96.9 35.3 1.1e-17 64.1 13.0 2.1 2 0 0 2 2 2 2 ATP synthase subunit C SR-25 PF10500.9 EAQ89754.1 - 3.6 7.2 12.1 0.66 9.5 0.5 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Metallophos PF00149.28 EAQ89756.1 - 1.5e-06 28.8 0.7 2.4e-06 28.2 0.7 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF1148 PF06618.11 EAQ89757.1 - 0.081 13.1 0.1 0.2 11.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1148) zf-C2H2 PF00096.26 EAQ89758.1 - 8.7e-05 22.8 1.6 8.7e-05 22.8 1.6 3.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type Zn_clus PF00172.18 EAQ89758.1 - 0.012 15.7 5.6 0.04 14.0 5.6 1.9 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-H2C2_2 PF13465.6 EAQ89758.1 - 1.7 9.2 15.0 2.5 8.7 1.3 4.4 4 0 0 4 4 4 0 Zinc-finger double domain Transpos_assoc PF13963.6 EAQ89758.1 - 2.4 8.5 6.4 11 6.4 0.1 3.1 3 0 0 3 3 3 0 Transposase-associated domain DDOST_48kD PF03345.14 EAQ89760.1 - 2.5e-138 461.4 0.0 3.5e-137 457.6 0.0 2.1 1 1 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta Beach PF02138.18 EAQ89760.1 - 1.3e-117 392.1 0.0 2.3e-117 391.3 0.0 1.4 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 EAQ89760.1 - 1.2e-10 41.4 0.0 4.1e-10 39.6 0.0 2.0 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.6 EAQ89760.1 - 2e-09 37.8 0.0 4.3e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily DUF4704 PF15787.5 EAQ89760.1 - 0.013 14.8 0.1 0.056 12.7 0.1 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4704) WD40 PF00400.32 EAQ89760.1 - 0.034 15.0 1.8 7.5 7.6 0.0 4.6 5 0 0 5 5 5 0 WD domain, G-beta repeat Peptidase_S8 PF00082.22 EAQ89761.1 - 1.1e-36 126.7 6.7 1.7e-36 126.0 6.7 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EAQ89761.1 - 3.2e-22 79.0 0.7 7.8e-22 77.7 0.7 1.7 1 0 0 1 1 1 1 Peptidase inhibitor I9 TryThrA_C PF12319.8 EAQ89762.1 - 0.04 13.4 0.5 0.13 11.8 0.1 1.8 2 0 0 2 2 2 0 Tryptophan-Threonine-rich plasmodium antigen C terminal Exonuc_X-T_C PF08411.10 EAQ89762.1 - 0.11 11.6 0.2 0.21 10.7 0.2 1.3 1 0 0 1 1 1 0 Exonuclease C-terminal FAD_binding_4 PF01565.23 EAQ89763.1 - 6.4e-21 74.5 2.7 1.7e-20 73.2 0.6 2.3 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 EAQ89763.1 - 2.7e-12 46.6 0.0 5.6e-12 45.6 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like NACHT PF05729.12 EAQ89764.1 - 5.4e-08 32.9 0.0 1.1e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 NACHT domain WD40 PF00400.32 EAQ89764.1 - 2.9e-06 27.9 11.9 4.7 8.2 0.1 7.9 8 1 1 9 9 9 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAQ89764.1 - 1.8e-05 24.9 0.0 5.7 7.3 0.0 5.9 3 2 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Nbas_N PF15492.6 EAQ89764.1 - 0.0038 16.6 0.2 3.2 7.0 0.0 3.3 3 1 1 4 4 4 2 Neuroblastoma-amplified sequence, N terminal TruB_C PF09142.11 EAQ89764.1 - 0.027 14.2 5.5 0.088 12.6 0.0 4.0 5 0 0 5 5 5 0 tRNA Pseudouridine synthase II, C terminal PD40 PF07676.12 EAQ89764.1 - 0.027 14.4 9.2 13 5.9 0.0 6.1 8 0 0 8 8 8 0 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 EAQ89764.1 - 0.99 8.3 6.6 12 4.7 1.9 4.4 3 2 0 5 5 5 0 WD40 region of Ge1, enhancer of mRNA-decapping protein 2OG-FeII_Oxy_2 PF13532.6 EAQ89767.1 - 1.6e-20 74.1 0.6 3.3e-20 73.1 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily PCM1_C PF15717.5 EAQ89767.1 - 0.36 9.5 5.1 0.55 8.9 5.1 1.1 1 0 0 1 1 1 0 Pericentriolar material 1 C terminus AMP-binding PF00501.28 EAQ89768.1 - 1.7e-33 115.8 0.4 1.3e-19 70.2 0.0 3.3 2 1 1 3 3 3 3 AMP-binding enzyme AMP-binding_C PF13193.6 EAQ89768.1 - 5.9e-17 62.4 0.2 2.8e-16 60.3 0.1 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Pyridoxal_deC PF00282.19 EAQ89769.1 - 1e-31 110.1 0.0 1.4e-31 109.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 EAQ89769.1 - 0.0095 14.9 0.0 0.017 14.1 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V dCache_3 PF14827.6 EAQ89769.1 - 0.11 12.1 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Double sensory domain of two-component sensor kinase Pirin PF02678.16 EAQ89770.1 - 1.9e-21 76.1 0.5 4.2e-20 71.8 0.5 2.3 1 1 0 1 1 1 1 Pirin Cupin_2 PF07883.11 EAQ89770.1 - 8.2e-07 28.6 2.9 0.00019 21.1 0.2 3.3 2 1 0 2 2 2 2 Cupin domain bVLRF1 PF18826.1 EAQ89772.1 - 9e-63 210.6 0.0 1.5e-62 209.9 0.0 1.4 1 0 0 1 1 1 1 bacteroidetes VLRF1 release factor Ank_5 PF13857.6 EAQ89772.1 - 6.9e-06 26.2 0.3 1.6e-05 25.1 0.3 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) zf-C2H2_3 PF13878.6 EAQ89772.1 - 0.32 10.9 1.1 0.82 9.5 0.0 2.1 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO CFEM PF05730.11 EAQ89773.1 - 2.6e-05 24.2 2.4 2.6e-05 24.2 2.4 2.6 2 0 0 2 2 2 1 CFEM domain SOG2 PF10428.9 EAQ89773.1 - 1.1 8.4 21.1 1.7 7.7 21.1 1.4 1 0 0 1 1 1 0 RAM signalling pathway protein T5orf172 PF10544.9 EAQ89774.1 - 1.9e-18 66.9 0.0 3.3e-18 66.1 0.0 1.3 1 0 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 EAQ89774.1 - 3.7e-09 37.1 0.0 5.8e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 Zn_clus PF00172.18 EAQ89776.1 - 1.6e-08 34.5 11.9 2.7e-08 33.8 11.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Annexin PF00191.20 EAQ89777.1 - 1.5e-18 66.6 2.9 0.00014 21.9 0.0 4.6 4 1 0 4 4 4 4 Annexin GPI2 PF06432.11 EAQ89779.1 - 1.8e-124 414.8 0.0 4e-124 413.6 0.0 1.6 1 1 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase DUF3573 PF12097.8 EAQ89779.1 - 0.071 11.9 0.2 0.11 11.3 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) SSP160 PF06933.11 EAQ89779.1 - 2 6.5 17.2 0.13 10.4 6.5 2.3 2 0 0 2 2 2 0 Special lobe-specific silk protein SSP160 DUF3439 PF11921.8 EAQ89779.1 - 4.3 7.3 11.0 1 9.3 4.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) CNH PF00780.22 EAQ89780.1 - 1.3e-67 228.4 0.0 2e-67 227.7 0.0 1.2 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.20 EAQ89780.1 - 1.9e-32 113.0 0.0 3.9e-32 112.0 0.0 1.5 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.6 EAQ89780.1 - 1.8e-09 37.8 0.2 2.6e-08 34.1 0.0 2.8 2 1 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 EAQ89780.1 - 1.1e-05 25.9 0.0 0.0013 19.2 0.0 2.9 2 0 0 2 2 2 1 PH domain PH_16 PF17838.1 EAQ89780.1 - 9.6e-05 22.2 0.0 0.022 14.6 0.0 2.4 2 0 0 2 2 2 2 PH domain Tropomyosin PF00261.20 EAQ89780.1 - 0.29 10.5 5.6 0.62 9.4 5.6 1.4 1 0 0 1 1 1 0 Tropomyosin Sod_Cu PF00080.20 EAQ89781.1 - 3.9e-45 153.5 7.2 4.5e-45 153.3 7.2 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) SNase PF00565.17 EAQ89782.1 - 2.4e-71 237.1 0.1 2e-22 79.7 0.0 5.4 5 0 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.24 EAQ89782.1 - 6e-24 84.4 0.0 1.6e-23 83.0 0.0 1.7 1 0 0 1 1 1 1 Tudor domain SMN PF06003.12 EAQ89782.1 - 1.5e-06 27.7 0.0 3.2e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) TAL_FSA PF00923.19 EAQ89783.1 - 1.1e-91 307.2 1.4 1.3e-91 306.9 1.4 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase Metallophos PF00149.28 EAQ89784.1 - 1.1e-07 32.6 0.0 1.6e-07 32.0 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EAQ89784.1 - 2.2e-06 28.0 0.1 3.3e-06 27.4 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain AAA_8 PF12780.7 EAQ89786.1 - 0.19 11.0 0.1 0.21 10.9 0.1 1.0 1 0 0 1 1 1 0 P-loop containing dynein motor region D4 Ag332 PF04671.12 EAQ89786.1 - 0.67 10.0 8.1 28 4.8 0.2 3.6 3 1 0 3 3 3 0 Erythrocyte membrane-associated giant protein antigen 332 DUF2689 PF10894.8 EAQ89786.1 - 1.1 9.1 3.8 20 5.0 1.0 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2689) Pet191_N PF10203.9 EAQ89787.1 - 2.1e-27 95.2 5.1 2.8e-27 94.8 5.1 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 COBRA PF04833.15 EAQ89787.1 - 0.057 13.3 1.0 0.095 12.6 1.0 1.6 1 1 0 1 1 1 0 COBRA-like protein CX9C PF16860.5 EAQ89787.1 - 0.087 12.9 3.4 4.9 7.3 0.5 2.5 2 0 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Cmc1 PF08583.10 EAQ89787.1 - 0.21 11.6 4.4 10 6.2 1.9 2.6 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Abhydrolase_1 PF00561.20 EAQ89788.1 - 2.6e-26 92.8 0.2 4e-26 92.2 0.2 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 EAQ89788.1 - 3.7e-22 77.7 0.0 6.8e-22 76.8 0.0 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Hydrolase_4 PF12146.8 EAQ89788.1 - 3e-05 23.4 0.0 0.047 12.9 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 FSH1 PF03959.13 EAQ89788.1 - 0.00088 19.0 0.0 0.84 9.2 0.0 2.2 2 0 0 2 2 2 2 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 EAQ89788.1 - 0.15 11.9 0.1 7.1 6.4 0.0 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase MMR_HSR1 PF01926.23 EAQ89789.1 - 1.6e-10 41.1 0.0 2.9e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 EAQ89789.1 - 0.0013 18.9 0.3 0.017 15.1 0.1 2.3 2 0 0 2 2 2 1 Dynamin family AAA_16 PF13191.6 EAQ89789.1 - 0.0071 16.8 0.2 0.018 15.4 0.2 1.7 1 0 0 1 1 1 1 AAA ATPase domain FeoB_N PF02421.18 EAQ89789.1 - 0.012 15.1 0.0 0.055 13.0 0.0 1.9 2 0 0 2 2 2 0 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EAQ89789.1 - 0.014 15.3 0.4 0.24 11.3 0.4 2.3 1 1 0 1 1 1 0 RsgA GTPase Arf PF00025.21 EAQ89789.1 - 0.044 13.2 0.0 0.073 12.5 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA_18 PF13238.6 EAQ89789.1 - 0.065 13.8 0.2 0.2 12.2 0.1 1.8 2 0 0 2 2 2 0 AAA domain PHD PF00628.29 EAQ89790.1 - 6.1e-10 38.8 1.9 6.1e-10 38.8 1.9 1.7 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.6 EAQ89790.1 - 0.0037 16.8 2.7 0.0065 16.0 2.7 1.4 1 0 0 1 1 1 1 PHD-finger zf-CW PF07496.15 EAQ89790.1 - 0.074 13.1 1.5 0.18 11.9 1.5 1.6 1 0 0 1 1 1 0 CW-type Zinc Finger Selenoprotein_S PF06936.11 EAQ89791.1 - 0.079 12.8 3.4 0.19 11.5 3.4 1.6 1 0 0 1 1 1 0 Selenoprotein S (SelS) TFIIA PF03153.13 EAQ89791.1 - 0.17 11.8 5.2 0.044 13.8 1.8 1.6 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Catalase-rel PF06628.12 EAQ89792.1 - 0.015 15.5 0.0 0.036 14.3 0.0 1.6 1 0 0 1 1 1 0 Catalase-related immune-responsive UvrD_C_2 PF13538.6 EAQ89793.1 - 8e-05 22.4 0.1 0.00047 19.9 0.0 2.3 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.14 EAQ89793.1 - 0.0011 17.0 0.0 0.0016 16.4 0.0 1.1 1 0 0 1 1 1 1 Helicase DUF5572 PF17733.1 EAQ89794.1 - 0.039 13.8 2.4 0.2 11.5 0.0 3.1 3 0 0 3 3 3 0 Family of unknown function (DUF5572) adh_short_C2 PF13561.6 EAQ89796.1 - 6.9e-42 143.6 0.0 1.4e-26 93.5 0.0 2.2 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EAQ89796.1 - 1.3e-27 96.6 0.0 1.5e-14 53.9 0.0 2.3 1 1 1 2 2 2 2 short chain dehydrogenase KR PF08659.10 EAQ89796.1 - 1.3e-08 35.0 0.0 2.1e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 EAQ89796.1 - 0.081 12.3 0.0 0.74 9.1 0.0 2.0 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Carboxyl_trans PF01039.22 EAQ89797.1 - 1.3e-131 439.7 0.2 1.6e-131 439.3 0.2 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 EAQ89797.1 - 0.0015 18.1 0.4 1.1 8.7 0.0 2.4 2 0 0 2 2 2 2 Malonate decarboxylase gamma subunit (MdcE) Acyl-CoA_dh_1 PF00441.24 EAQ89798.1 - 2.8e-43 147.7 3.1 6e-43 146.6 3.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EAQ89798.1 - 6.7e-31 107.3 0.0 1.4e-30 106.2 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EAQ89798.1 - 6.2e-27 93.6 0.1 1.2e-26 92.7 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EAQ89798.1 - 4.4e-15 56.1 1.1 9.7e-15 55.0 1.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 EAQ89798.1 - 0.00016 21.4 0.1 0.0004 20.1 0.1 1.6 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal NUDIX PF00293.28 EAQ89800.1 - 5.4e-09 36.2 0.1 4.9e-08 33.1 0.1 2.0 1 1 0 1 1 1 1 NUDIX domain DLH PF01738.18 EAQ89801.1 - 9.9e-09 35.1 0.1 4.6e-08 32.9 0.1 1.8 1 1 0 1 1 1 1 Dienelactone hydrolase family Zn_ribbon_17 PF17120.5 EAQ89802.1 - 5.1e-07 29.2 13.8 1.1e-06 28.1 13.8 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type WD40 PF00400.32 EAQ89802.1 - 9.5e-06 26.3 6.2 0.0035 18.1 0.2 4.2 3 0 0 3 3 3 1 WD domain, G-beta repeat RWD PF05773.22 EAQ89802.1 - 0.0016 18.7 0.0 0.003 17.8 0.0 1.4 1 0 0 1 1 1 1 RWD domain zf-RING_2 PF13639.6 EAQ89802.1 - 0.9 9.9 10.4 1.9 8.9 10.4 1.6 1 0 0 1 1 1 0 Ring finger domain UQ_con PF00179.26 EAQ89803.1 - 7e-18 64.6 0.0 3.3e-10 39.8 0.0 2.0 1 1 1 2 2 2 2 Ubiquitin-conjugating enzyme ADH_zinc_N PF00107.26 EAQ89804.1 - 1.2e-13 51.2 0.0 2.1e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EAQ89804.1 - 0.0017 19.4 0.0 0.0029 18.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Ribosomal_L12 PF00542.19 EAQ89804.1 - 0.042 14.2 0.1 0.11 12.9 0.1 1.7 1 0 0 1 1 1 0 Ribosomal protein L7/L12 C-terminal domain PI3Ka PF00613.20 EAQ89805.1 - 2.6e-57 193.2 1.0 4.3e-57 192.5 1.0 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 EAQ89805.1 - 1.8e-45 155.7 0.1 1.6e-30 106.7 0.0 2.5 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 EAQ89805.1 - 4.7e-27 94.6 0.1 8.8e-27 93.7 0.1 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 Nse4_C PF08743.10 EAQ89806.1 - 6.9e-35 119.2 0.0 4.5e-34 116.6 0.0 2.5 2 0 0 2 2 2 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.6 EAQ89806.1 - 6.7e-18 64.5 0.1 3.2e-17 62.4 0.0 2.2 2 0 0 2 2 2 1 Binding domain of Nse4/EID3 to Nse3-MAGE UPF0302 PF08864.10 EAQ89806.1 - 0.038 14.0 0.0 0.18 11.9 0.0 2.2 2 0 0 2 2 2 0 UPF0302 domain VP4_helical PF17478.2 EAQ89806.1 - 0.072 12.5 0.5 15 4.9 0.1 3.1 3 0 0 3 3 3 0 Rotavirus VP4 helical domain GFD1 PF17331.2 EAQ89806.1 - 8.9 6.6 7.9 4.1 7.7 0.5 3.3 3 0 0 3 3 3 0 GFD1 mRNA transport factor DUF1062 PF06353.12 EAQ89807.1 - 0.013 16.3 0.7 0.027 15.3 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1062) Lipase_3 PF01764.25 EAQ89808.1 - 3.3e-11 43.2 0.0 6.2e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 EAQ89808.1 - 0.077 13.6 0.1 0.15 12.6 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase family DUF4336 PF14234.6 EAQ89809.1 - 2.9e-08 33.3 0.0 1.3e-07 31.1 0.0 2.0 3 0 0 3 3 3 1 Domain of unknown function (DUF4336) Amidase PF01425.21 EAQ89810.1 - 2.2e-100 336.7 3.1 1.1e-99 334.5 3.1 1.9 1 1 0 1 1 1 1 Amidase PRP38 PF03371.15 EAQ89811.1 - 4.5e-40 137.4 0.0 2.7e-25 89.2 0.0 2.1 1 1 1 2 2 2 2 PRP38 family PRP38_assoc PF12871.7 EAQ89811.1 - 4.6e-11 43.2 42.5 4.6e-11 43.2 42.5 2.0 2 1 0 2 2 2 1 Pre-mRNA-splicing factor 38-associated hydrophilic C-term PI3K_1B_p101 PF10486.9 EAQ89811.1 - 0.0014 16.5 3.1 0.0017 16.2 3.1 1.0 1 0 0 1 1 1 1 Phosphoinositide 3-kinase gamma adapter protein p101 subunit RSRP PF17069.5 EAQ89811.1 - 0.048 13.2 41.2 0.07 12.7 41.2 1.2 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 CDC45 PF02724.14 EAQ89811.1 - 1 7.6 15.1 1.3 7.2 15.1 1.1 1 0 0 1 1 1 0 CDC45-like protein RAP1 PF07218.11 EAQ89811.1 - 3.4 5.8 6.6 4.2 5.5 6.6 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) MDFI PF15316.6 EAQ89811.1 - 3.7 7.6 5.6 5.7 7.0 5.6 1.3 1 0 0 1 1 1 0 MyoD family inhibitor MmgE_PrpD PF03972.14 EAQ89813.1 - 7.5e-132 440.0 0.6 4.5e-131 437.4 0.6 1.8 1 1 0 1 1 1 1 MmgE/PrpD family DUF2383 PF09537.10 EAQ89813.1 - 0.14 12.5 0.0 0.4 11.0 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF2383) WD40 PF00400.32 EAQ89814.1 - 6.3e-16 58.5 25.6 0.00038 21.2 0.5 7.2 6 1 0 6 6 6 5 WD domain, G-beta repeat PD40 PF07676.12 EAQ89814.1 - 6.4e-05 22.8 0.6 0.015 15.2 0.0 3.2 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat ANAPC4_WD40 PF12894.7 EAQ89814.1 - 0.0011 19.2 0.0 0.059 13.7 0.0 2.7 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 EAQ89814.1 - 0.16 12.5 0.7 32 5.2 0.2 3.0 2 0 0 2 2 2 0 PQQ-like domain RRM_1 PF00076.22 EAQ89815.1 - 0.0031 17.3 0.0 0.0053 16.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 EAQ89815.1 - 0.2 11.9 0.1 0.29 11.3 0.1 1.2 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter SET PF00856.28 EAQ89816.1 - 0.2 12.0 0.0 0.29 11.5 0.0 1.2 1 0 0 1 1 1 0 SET domain Coq4 PF05019.13 EAQ89817.1 - 1.9e-77 259.5 0.0 2.3e-77 259.2 0.0 1.0 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 dsDNA_bind PF01984.20 EAQ89818.1 - 2.1e-40 137.4 13.3 2.5e-40 137.2 13.3 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain Fes1 PF08609.10 EAQ89818.1 - 0.024 15.5 1.7 0.031 15.2 0.7 1.6 1 1 0 1 1 1 0 Nucleotide exchange factor Fes1 ApbA_C PF08546.11 EAQ89819.1 - 2.1e-19 69.9 0.0 3.1e-19 69.4 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 EAQ89819.1 - 2.7e-17 62.8 0.0 3.9e-17 62.3 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Peptidase_M90 PF06167.12 EAQ89819.1 - 0.033 13.8 0.0 0.055 13.1 0.0 1.3 1 0 0 1 1 1 0 Glucose-regulated metallo-peptidase M90 Sas10_Utp3 PF04000.15 EAQ89820.1 - 8.3e-17 61.6 1.1 4.8e-16 59.1 0.1 2.0 2 0 0 2 2 2 1 Sas10/Utp3/C1D family DUF2076 PF09849.9 EAQ89821.1 - 5.6e-06 26.6 20.7 1.7e-05 25.1 20.7 1.6 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.13 EAQ89821.1 - 0.00041 20.4 4.3 0.0006 19.9 4.3 1.3 1 0 0 1 1 1 1 CHCH domain GCK PF07802.11 EAQ89821.1 - 0.0033 17.8 0.5 0.0056 17.1 0.5 1.4 1 1 0 1 1 1 1 GCK domain Trypan_glycop_C PF10659.9 EAQ89821.1 - 0.0073 16.7 4.0 0.0073 16.7 4.0 1.4 2 0 0 2 2 2 1 Trypanosome variant surface glycoprotein C-terminal domain DUF759 PF05537.11 EAQ89821.1 - 0.16 10.8 0.1 0.19 10.6 0.1 1.1 1 0 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF759) CX9C PF16860.5 EAQ89821.1 - 1.1 9.3 5.7 1.1 9.3 1.7 1.8 1 1 1 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, UBX PF00789.20 EAQ89822.1 - 2e-15 56.7 0.0 3.7e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 UBX domain SelK_SelG PF10961.8 EAQ89822.1 - 0.046 14.3 0.3 0.16 12.6 0.3 1.9 1 0 0 1 1 1 0 Selenoprotein SelK_SelG TFIIA PF03153.13 EAQ89822.1 - 2.5 8.0 15.2 0.22 11.5 11.0 1.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit PBP_sp32 PF07222.12 EAQ89822.1 - 3.2 7.2 11.1 5.6 6.3 11.1 1.4 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Neur_chan_memb PF02932.16 EAQ89822.1 - 6.4 6.8 6.9 12 5.9 6.9 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SURF1 PF02104.15 EAQ89823.1 - 4.9e-45 153.9 0.2 6.2e-45 153.6 0.2 1.1 1 0 0 1 1 1 1 SURF1 family CENP-T_C PF15511.6 EAQ89824.1 - 1.1e-48 163.8 0.0 1.9e-48 163.1 0.0 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 EAQ89824.1 - 1.5e-09 38.1 0.0 2.5e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 EAQ89824.1 - 9.8e-05 22.6 0.0 0.00018 21.7 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EAQ89824.1 - 0.00037 20.9 0.0 0.00081 19.8 0.0 1.6 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 DUF1957 PF09210.11 EAQ89824.1 - 0.16 12.3 0.1 0.29 11.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1957) Ras PF00071.22 EAQ89825.1 - 5.1e-51 172.5 0.0 6.1e-51 172.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAQ89825.1 - 3.8e-21 75.5 0.0 5.5e-21 75.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAQ89825.1 - 2.3e-06 27.2 0.0 3.3e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RRM_1 PF00076.22 EAQ89826.1 - 8.5e-11 41.5 0.5 2.1e-10 40.2 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4133 PF13571.6 EAQ89827.1 - 0.061 13.7 0.1 0.12 12.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4133) Edc3_linker PF16598.5 EAQ89827.1 - 0.067 13.9 0.7 0.22 12.2 0.1 2.0 2 0 0 2 2 2 0 Linker region of enhancer of mRNA-decapping protein 3 TraL PF07178.11 EAQ89827.1 - 0.15 12.6 0.1 0.35 11.4 0.1 1.6 1 0 0 1 1 1 0 TraL protein DUF3357 PF11837.8 EAQ89828.1 - 0.062 13.8 0.0 0.19 12.2 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) RNA_pol_Rpb1_6 PF04992.14 EAQ89828.1 - 0.096 12.5 0.2 2.1 8.1 0.1 2.1 2 0 0 2 2 2 0 RNA polymerase Rpb1, domain 6 EGF_2 PF07974.13 EAQ89828.1 - 9.2 6.7 12.6 16 5.9 12.6 1.4 1 0 0 1 1 1 0 EGF-like domain Ras PF00071.22 EAQ89830.1 - 3.4e-32 111.3 0.0 9e-19 67.6 0.0 2.1 1 1 1 2 2 2 2 Ras family Roc PF08477.13 EAQ89830.1 - 2e-06 28.0 0.1 0.00036 20.7 0.0 2.2 1 1 1 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAQ89830.1 - 0.029 13.8 0.0 0.14 11.6 0.0 1.9 1 1 1 2 2 2 0 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EAQ89830.1 - 0.071 13.0 0.0 1.3 8.9 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase DUF4535 PF15054.6 EAQ89831.1 - 0.082 12.7 0.1 0.15 11.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4535) CMS1 PF14617.6 EAQ89832.1 - 4e-46 157.4 1.6 4.4e-46 157.3 1.6 1.0 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit Med19 PF10278.9 EAQ89832.1 - 0.26 11.2 10.9 0.72 9.8 9.6 1.9 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 PI-PLC-X PF00388.19 EAQ89834.1 - 7.2e-56 187.8 0.0 1.9e-55 186.4 0.0 1.7 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 EAQ89834.1 - 2.3e-38 131.1 0.0 4.2e-38 130.2 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 EAQ89834.1 - 0.061 13.6 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 C2 domain RdRP PF05183.12 EAQ89840.1 - 1.3e-183 611.8 0.0 1.7e-183 611.5 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase FAD-oxidase_C PF02913.19 EAQ89841.1 - 1.5e-49 168.9 0.1 2.4e-49 168.2 0.1 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 EAQ89841.1 - 2.7e-33 114.6 0.0 5.1e-33 113.7 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Ribosomal_S4e PF00900.20 EAQ89843.1 - 1.3e-36 124.3 0.2 3.3e-36 123.0 0.2 1.7 1 0 0 1 1 1 1 Ribosomal family S4e 40S_S4_C PF16121.5 EAQ89843.1 - 2.7e-23 81.3 0.1 4.4e-23 80.7 0.1 1.4 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 EAQ89843.1 - 4.3e-19 68.3 5.3 8.6e-19 67.4 5.3 1.5 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.25 EAQ89843.1 - 1.4e-06 27.9 0.0 2.7e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 S4 domain KOW PF00467.29 EAQ89843.1 - 2.6e-05 24.0 1.3 2.6e-05 24.0 1.3 3.1 4 0 0 4 4 4 1 KOW motif Sipho_tail PF05709.11 EAQ89843.1 - 0.12 11.8 0.0 0.21 11.0 0.0 1.4 1 1 0 1 1 1 0 Phage tail protein Myb_DNA-binding PF00249.31 EAQ89844.1 - 4.5e-17 62.0 0.1 5.3e-10 39.3 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAQ89844.1 - 5.3e-11 42.6 0.1 0.00015 22.0 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EAQ89844.1 - 0.00012 22.1 0.0 0.15 12.1 0.0 2.5 2 0 0 2 2 2 2 SLIDE SANT_DAMP1_like PF16282.5 EAQ89844.1 - 0.024 14.8 0.0 0.12 12.6 0.0 2.0 2 0 0 2 2 2 0 SANT/Myb-like domain of DAMP1 Glyco_hydro_18 PF00704.28 EAQ89845.1 - 5.3e-22 79.0 0.9 1.6e-21 77.3 0.9 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.20 EAQ89845.1 - 2.1e-07 30.9 0.0 4e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 LysM domain Mid2 PF04478.12 EAQ89846.1 - 0.00012 21.9 2.1 0.00012 21.9 2.1 1.8 2 0 0 2 2 2 1 Mid2 like cell wall stress sensor SOG2 PF10428.9 EAQ89846.1 - 0.079 12.2 16.2 0.087 12.0 16.2 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein SPX PF03105.19 EAQ89846.1 - 0.26 11.1 15.4 0.3 11.0 15.4 1.2 1 0 0 1 1 1 0 SPX domain PARM PF17061.5 EAQ89846.1 - 0.55 10.3 29.5 0.91 9.6 29.5 1.3 1 0 0 1 1 1 0 PARM PAM2 PF07145.15 EAQ89848.1 - 0.00032 20.2 12.8 0.28 11.0 1.2 4.7 5 0 0 5 5 5 3 Ataxin-2 C-terminal region Tht1 PF04163.12 EAQ89848.1 - 0.74 8.5 2.9 1.2 7.8 2.9 1.2 1 0 0 1 1 1 0 Tht1-like nuclear fusion protein zf-C2H2 PF00096.26 EAQ89849.1 - 1.3e-10 41.1 7.8 1.3e-05 25.3 2.3 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EAQ89849.1 - 4.8e-07 30.1 6.3 0.012 16.4 1.3 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EAQ89849.1 - 2.9e-06 27.4 10.6 0.00039 20.7 0.3 2.8 3 0 0 3 3 2 2 Zinc-finger double domain BolA PF01722.18 EAQ89849.1 - 0.025 14.9 0.3 2.4 8.5 0.0 2.3 1 1 1 2 2 2 0 BolA-like protein zf-C2H2_8 PF15909.5 EAQ89849.1 - 0.061 13.6 0.7 0.15 12.4 0.7 1.6 1 0 0 1 1 1 0 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 EAQ89849.1 - 0.16 12.3 3.1 2.1 8.7 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 EAQ89849.1 - 0.39 10.5 3.5 21 5.0 0.1 3.2 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-C2HE PF16278.5 EAQ89849.1 - 0.56 10.7 7.0 0.54 10.8 1.5 2.2 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-met PF12874.7 EAQ89849.1 - 0.63 10.5 2.3 1.4 9.4 0.0 2.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-LYAR PF08790.11 EAQ89849.1 - 0.67 9.9 2.7 2.3 8.2 0.2 2.2 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-C2H2_6 PF13912.6 EAQ89849.1 - 2.1 8.5 3.9 9.2 6.4 0.3 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger Ctr PF04145.15 EAQ89850.1 - 1e-15 58.7 0.0 1.3e-15 58.3 0.0 1.1 1 0 0 1 1 1 1 Ctr copper transporter family YAcAr PF10686.9 EAQ89850.1 - 0.029 14.3 0.9 0.088 12.8 0.1 2.0 2 0 0 2 2 2 0 YspA, cpYpsA-related SLOG family SRF-TF PF00319.18 EAQ89851.1 - 1.5e-20 72.4 0.1 2.2e-20 71.8 0.1 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Srg PF02118.21 EAQ89853.1 - 0.004 16.8 0.6 0.0057 16.3 0.2 1.5 2 0 0 2 2 2 1 Srg family chemoreceptor TctB PF07331.11 EAQ89853.1 - 0.035 14.4 3.8 0.2 11.9 1.1 2.2 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family DUF373 PF04123.13 EAQ89853.1 - 0.1 12.0 0.3 0.13 11.7 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DUF2700 PF10912.8 EAQ89853.1 - 0.29 11.2 6.3 0.13 12.3 2.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2700) Mg_trans_NIPA PF05653.14 EAQ89854.1 - 1.3e-15 57.4 6.7 2e-15 56.7 6.7 1.2 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 EAQ89854.1 - 2.4e-06 27.8 12.4 0.00039 20.6 0.3 2.5 2 0 0 2 2 2 2 EamA-like transporter family PUNUT PF16913.5 EAQ89854.1 - 0.00014 21.2 0.1 0.00014 21.2 0.1 2.0 2 0 0 2 2 2 1 Purine nucleobase transmembrane transport UAA PF08449.11 EAQ89854.1 - 0.013 14.7 0.2 0.03 13.5 0.1 1.7 1 1 0 1 1 1 0 UAA transporter family Multi_Drug_Res PF00893.19 EAQ89854.1 - 2.9 8.6 7.7 24 5.7 0.2 2.9 2 1 0 2 2 2 0 Small Multidrug Resistance protein vATP-synt_E PF01991.18 EAQ89855.1 - 7.4e-69 231.1 4.7 8.7e-69 230.9 4.7 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit FliH PF02108.16 EAQ89855.1 - 0.0096 16.0 0.0 0.029 14.4 0.0 1.9 2 1 0 2 2 2 1 Flagellar assembly protein FliH DLH PF01738.18 EAQ89855.1 - 0.12 11.9 1.3 0.13 11.8 0.1 1.6 2 0 0 2 2 2 0 Dienelactone hydrolase family IL10 PF00726.17 EAQ89856.1 - 0.12 11.9 0.0 0.27 10.7 0.0 1.5 1 0 0 1 1 1 0 Interleukin 10 bPH_3 PF14470.6 EAQ89857.1 - 0.12 12.8 0.0 0.23 11.9 0.0 1.5 1 0 0 1 1 1 0 Bacterial PH domain PhoLip_ATPase_C PF16212.5 EAQ89858.1 - 3.7e-75 252.9 25.9 3.7e-75 252.9 25.9 2.1 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EAQ89858.1 - 4e-17 61.7 1.8 9.9e-17 60.4 1.8 1.6 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 EAQ89858.1 - 5.3e-14 52.1 0.0 2.9e-13 49.7 0.0 2.2 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EAQ89858.1 - 7.3e-11 42.7 5.2 5e-07 30.2 1.9 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 EAQ89858.1 - 0.0027 17.2 0.0 0.013 15.1 0.0 2.2 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 EAQ89858.1 - 0.05 13.3 0.6 0.12 12.1 0.6 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Aldedh PF00171.22 EAQ89859.1 - 6.5e-114 381.0 0.0 7.9e-114 380.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family GATA PF00320.27 EAQ89860.1 - 2e-16 59.3 2.3 3.7e-16 58.4 2.3 1.5 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.10 EAQ89860.1 - 3.8e-10 39.4 0.5 7.7e-10 38.4 0.5 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Hist_rich_Ca-bd PF10529.9 EAQ89861.1 - 1.8 8.9 9.4 2.9 8.2 9.4 1.3 1 0 0 1 1 1 0 Histidine-rich Calcium-binding repeat region Pkinase_C PF00433.24 EAQ89862.1 - 0.0001 23.0 0.9 0.00019 22.1 0.9 1.5 1 0 0 1 1 1 1 Protein kinase C terminal domain Tricorn_C1 PF14684.6 EAQ89862.1 - 0.022 14.8 1.1 0.043 13.9 0.3 1.7 1 1 1 2 2 2 0 Tricorn protease C1 domain Pkinase PF00069.25 EAQ89863.1 - 2.8e-40 138.4 0.0 3.8e-40 137.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ89863.1 - 2e-20 73.2 0.0 2.8e-20 72.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAQ89863.1 - 0.0023 17.3 0.1 0.0095 15.3 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 EAQ89863.1 - 0.0051 16.8 0.3 0.039 13.9 0.3 2.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EAQ89863.1 - 0.013 14.5 0.0 0.024 13.6 0.0 1.4 1 1 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 EAQ89863.1 - 0.017 14.5 0.0 0.034 13.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 EAQ89863.1 - 0.2 10.7 0.0 0.31 10.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Wbp11 PF09429.10 EAQ89864.1 - 2.2e-22 79.2 12.6 2.2e-22 79.2 12.6 2.1 2 0 0 2 2 2 1 WW domain binding protein 11 PAG PF15347.6 EAQ89864.1 - 0.012 14.7 0.5 0.012 14.7 0.5 1.4 2 0 0 2 2 2 0 Phosphoprotein associated with glycosphingolipid-enriched ICAT PF06384.11 EAQ89864.1 - 0.12 12.6 1.6 0.19 12.0 0.4 1.9 2 0 0 2 2 2 0 Beta-catenin-interacting protein ICAT Lipoprotein_7 PF01540.16 EAQ89864.1 - 0.34 10.2 4.6 0.53 9.5 4.6 1.2 1 0 0 1 1 1 0 Adhesin lipoprotein Strep_SA_rep PF06696.11 EAQ89864.1 - 5.3 7.2 8.6 1.9 8.6 5.0 2.2 2 0 0 2 2 2 0 Streptococcal surface antigen repeat ApbA PF02558.16 EAQ89865.1 - 3.7e-25 88.3 0.0 5.3e-25 87.8 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 EAQ89865.1 - 1.8e-18 67.0 0.0 2.6e-18 66.4 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal DEAD PF00270.29 EAQ89866.1 - 4.8e-40 137.2 0.0 7.9e-40 136.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EAQ89866.1 - 2e-25 89.3 0.3 6.2e-24 84.5 0.1 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EAQ89866.1 - 2.5e-09 37.4 0.0 5.8e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF4844 PF16133.5 EAQ89866.1 - 0.07 13.7 0.5 0.2 12.2 0.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4844) CMS1 PF14617.6 EAQ89866.1 - 0.088 12.1 0.0 0.28 10.5 0.0 1.8 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit Cyclin PF08613.11 EAQ89867.1 - 1.6e-05 25.3 1.2 1.6e-05 25.3 1.2 2.4 2 1 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 EAQ89867.1 - 0.0077 16.0 0.2 0.015 15.1 0.2 1.5 1 1 0 1 1 1 1 Cyclin, N-terminal domain CorA PF01544.18 EAQ89869.1 - 2.6e-13 50.0 0.5 3.9e-13 49.4 0.5 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DDE_Tnp_ISL3 PF01610.17 EAQ89869.1 - 0.0033 17.2 0.1 0.0052 16.5 0.1 1.2 1 0 0 1 1 1 1 Transposase DUF4199 PF13858.6 EAQ89869.1 - 0.13 12.6 0.3 0.23 11.9 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) PWWP PF00855.17 EAQ89870.1 - 0.1 13.0 0.1 0.2 12.1 0.1 1.4 1 0 0 1 1 1 0 PWWP domain Ribosomal_S30 PF04758.14 EAQ89871.1 - 1.9e-30 104.8 8.7 2e-30 104.7 8.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 Pyrid_oxidase_2 PF13883.6 EAQ89872.1 - 1.5e-40 138.9 0.0 2.4e-40 138.3 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Robl_LC7 PF03259.17 EAQ89874.1 - 9.5e-10 38.1 0.0 1.3e-07 31.3 0.0 2.1 2 0 0 2 2 2 2 Roadblock/LC7 domain Ipi1_N PF12333.8 EAQ89875.1 - 3.8e-06 27.4 1.0 1.8e-05 25.3 0.0 2.4 2 0 0 2 2 2 1 Rix1 complex component involved in 60S ribosome maturation DUF4519 PF15012.6 EAQ89875.1 - 0.72 10.1 5.5 3.1 8.1 4.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) DEAD PF00270.29 EAQ89876.1 - 2.5e-36 125.1 0.0 3.9e-36 124.4 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EAQ89876.1 - 9e-26 90.4 0.0 4.7e-25 88.1 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 EAQ89876.1 - 2.5e-05 23.2 0.0 3.7e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain UTP25 PF06862.12 EAQ89876.1 - 0.0013 17.6 0.0 0.079 11.7 0.0 2.5 2 1 1 3 3 3 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 SecA_DEAD PF07517.14 EAQ89876.1 - 0.024 13.9 0.2 0.12 11.6 0.0 1.9 2 0 0 2 2 2 0 SecA DEAD-like domain Acatn PF13000.7 EAQ89877.1 - 8.7e-144 480.0 18.9 1.4e-82 278.0 8.5 3.4 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 CENP-O PF09496.10 EAQ89878.1 - 7.8e-70 235.2 0.0 3.2e-69 233.2 0.0 1.8 2 0 0 2 2 2 1 Cenp-O kinetochore centromere component Securin PF04856.13 EAQ89878.1 - 0.079 12.9 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Securin sister-chromatid separation inhibitor Pox_A_type_inc PF04508.12 EAQ89878.1 - 0.09 12.7 0.9 0.19 11.6 0.9 1.5 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat MFS_1 PF07690.16 EAQ89880.1 - 8.9e-39 133.4 30.3 2.4e-33 115.5 27.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EAQ89880.1 - 1e-07 31.2 4.9 1.9e-07 30.3 4.9 1.5 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_5 PF05631.14 EAQ89880.1 - 8.2e-06 25.0 1.4 1.2e-05 24.4 1.4 1.3 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1_like PF12832.7 EAQ89880.1 - 0.0019 17.1 0.8 0.019 13.9 0.8 2.8 1 1 0 1 1 1 1 MFS_1 like family DUF3621 PF12285.8 EAQ89880.1 - 0.38 11.2 1.7 13 6.3 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3621) fn3_2 PF16893.5 EAQ89881.1 - 8.5e-39 131.6 0.1 1.5e-38 130.8 0.1 1.4 1 0 0 1 1 1 1 Fibronectin type III domain CHS5_N PF16892.5 EAQ89881.1 - 1.7e-13 50.3 2.4 1.4e-12 47.3 2.4 2.2 1 1 0 1 1 1 1 Chitin biosynthesis protein CHS5 N-terminus PTCB-BRCT PF12738.7 EAQ89881.1 - 2.1e-12 46.8 0.0 4.3e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 EAQ89881.1 - 7.2e-11 42.3 0.0 1.2e-10 41.6 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 EAQ89881.1 - 0.00056 20.3 0.0 0.0013 19.1 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain fn3 PF00041.21 EAQ89881.1 - 0.0065 16.8 0.0 0.033 14.5 0.0 2.2 1 1 0 1 1 1 1 Fibronectin type III domain VIR_N PF15912.5 EAQ89881.1 - 1.6 8.3 14.7 2.9 7.4 14.7 1.3 1 0 0 1 1 1 0 Virilizer, N-terminal Dicty_REP PF05086.12 EAQ89881.1 - 3.7 5.4 6.1 5.1 4.9 6.1 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DFP PF04127.15 EAQ89882.1 - 5.4e-14 52.4 0.0 6.1e-06 26.2 0.0 3.1 2 1 1 3 3 3 3 DNA / pantothenate metabolism flavoprotein eIF-1a PF01176.19 EAQ89884.1 - 1e-16 60.5 0.0 1.4e-16 60.0 0.0 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 WH1 PF00568.23 EAQ89885.1 - 3e-29 101.2 0.2 4.1e-29 100.8 0.2 1.2 1 0 0 1 1 1 1 WH1 domain WH2 PF02205.20 EAQ89885.1 - 0.0042 16.9 0.2 0.0095 15.7 0.2 1.6 1 0 0 1 1 1 1 WH2 motif ERCC4 PF02732.15 EAQ89887.1 - 3.2e-19 69.7 0.0 8.5e-19 68.3 0.0 1.8 2 0 0 2 2 2 1 ERCC4 domain DUF4780 PF16012.5 EAQ89887.1 - 0.13 11.7 0.1 11 5.4 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4780) AAA_23 PF13476.6 EAQ89889.1 - 2.3e-18 67.4 0.3 2.3e-18 67.4 0.3 4.6 3 1 0 3 3 3 1 AAA domain SMC_N PF02463.19 EAQ89889.1 - 1.8e-14 53.7 17.4 2.9e-13 49.8 5.2 4.1 3 2 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 EAQ89889.1 - 2.3e-10 40.7 6.5 1.2e-08 35.1 0.0 3.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 EAQ89889.1 - 0.0043 16.9 0.0 0.011 15.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EAQ89889.1 - 0.0063 16.2 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain Glyco_hydro_4 PF02056.16 EAQ89889.1 - 0.028 14.0 0.8 8.4 5.9 0.1 3.3 3 0 0 3 3 3 0 Family 4 glycosyl hydrolase AAA PF00004.29 EAQ89889.1 - 0.036 14.5 0.5 0.89 10.0 0.0 3.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 EAQ89889.1 - 0.69 9.8 3.0 1.7 8.6 0.0 3.2 3 0 0 3 3 3 0 RsgA GTPase RNA_pol_Rpb5_C PF01191.19 EAQ89889.1 - 3.2 7.7 5.1 15 5.5 0.0 4.0 4 0 0 4 4 4 0 RNA polymerase Rpb5, C-terminal domain Pkinase PF00069.25 EAQ89890.1 - 6.5e-69 232.2 0.7 8.2e-68 228.6 0.7 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ89890.1 - 1e-37 129.9 0.3 2.7e-35 121.9 0.1 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Fungal_KA1 PF16797.5 EAQ89890.1 - 6.5e-22 77.5 3.2 1.6e-11 43.9 0.2 2.8 1 1 1 2 2 2 2 Fungal kinase associated-1 domain Haspin_kinase PF12330.8 EAQ89890.1 - 0.00026 20.0 0.0 0.00061 18.8 0.0 1.6 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EAQ89890.1 - 0.0012 18.3 0.0 0.0033 16.8 0.0 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EAQ89890.1 - 0.0014 18.0 0.0 0.0029 17.0 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.20 EAQ89890.1 - 0.0033 17.0 0.2 0.0074 15.9 0.2 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 EAQ89890.1 - 0.0063 16.5 0.3 0.037 13.9 0.0 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family Lyase_1 PF00206.20 EAQ89891.1 - 2.8e-69 233.9 0.0 4.5e-69 233.2 0.0 1.3 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 EAQ89891.1 - 5.3e-22 78.0 0.1 1.2e-21 76.8 0.1 1.7 1 0 0 1 1 1 1 Fumarase C C-terminus Malate_synthase PF01274.22 EAQ89892.1 - 2.5e-77 260.4 0.0 2.9e-77 260.1 0.0 1.0 1 0 0 1 1 1 1 Malate synthase Malate_synthase PF01274.22 EAQ89893.1 - 1.2e-60 205.3 0.7 9.3e-60 202.4 0.7 1.9 1 1 0 1 1 1 1 Malate synthase Amidase PF01425.21 EAQ89894.1 - 5.5e-83 279.4 0.2 7e-83 279.1 0.2 1.1 1 0 0 1 1 1 1 Amidase ACT_7 PF13840.6 EAQ89894.1 - 0.09 12.6 0.4 0.41 10.5 0.1 2.1 2 0 0 2 2 2 0 ACT domain Per1 PF04080.13 EAQ89894.1 - 0.14 11.9 0.3 0.2 11.4 0.3 1.3 1 0 0 1 1 1 0 Per1-like family SEN1_N PF12726.7 EAQ89896.1 - 1e-207 691.9 0.2 1.3e-207 691.6 0.2 1.1 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.6 EAQ89896.1 - 1.1e-71 241.6 0.5 1.1e-71 241.6 0.5 2.2 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.6 EAQ89896.1 - 3.2e-62 209.7 0.0 5.4e-62 209.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EAQ89896.1 - 1.5e-09 37.8 0.6 7.3e-06 25.8 0.2 2.6 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 EAQ89896.1 - 2.6e-09 37.6 0.1 7e-09 36.2 0.1 1.7 1 0 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 EAQ89896.1 - 6.1e-06 26.0 0.0 0.001 18.7 0.0 2.8 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.18 EAQ89896.1 - 1.6e-05 24.8 0.4 0.016 15.0 0.0 3.3 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase HhH-GPD PF00730.25 EAQ89897.1 - 2.5e-07 31.1 0.0 7.7e-07 29.5 0.0 1.8 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein DNA_methylase PF00145.17 EAQ89899.1 - 5.7e-39 134.4 0.0 1e-29 104.0 0.0 2.2 1 1 1 2 2 2 2 C-5 cytosine-specific DNA methylase EAF PF09816.9 EAQ89900.1 - 2.3e-22 79.3 0.1 5.1e-22 78.2 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor CBM_6 PF03422.15 EAQ89900.1 - 0.12 12.7 0.1 0.25 11.6 0.1 1.5 1 0 0 1 1 1 0 Carbohydrate binding module (family 6) Nucleo_P87 PF07267.11 EAQ89900.1 - 8.5 5.1 11.6 0.39 9.5 5.9 1.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 Glyco_hydro_76 PF03663.14 EAQ89901.1 - 1.6e-149 498.4 18.3 2.2e-149 498.0 18.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 p450 PF00067.22 EAQ89901.1 - 4.5e-61 207.0 0.0 6.4e-61 206.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 IMD PF08397.11 EAQ89904.1 - 0.065 12.6 0.6 6.7 6.0 0.0 2.1 2 0 0 2 2 2 0 IRSp53/MIM homology domain Abhydrolase_2 PF02230.16 EAQ89905.1 - 1.2e-62 211.6 0.0 1.5e-62 211.3 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 EAQ89905.1 - 4.9e-08 32.5 0.8 0.00019 20.8 0.0 3.0 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EAQ89905.1 - 6.8e-06 25.7 0.5 0.00044 19.8 0.0 2.5 3 0 0 3 3 3 1 Prolyl oligopeptidase family FSH1 PF03959.13 EAQ89905.1 - 7.1e-06 25.8 0.0 2.2e-05 24.2 0.0 1.7 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 EAQ89905.1 - 1.7e-05 25.6 0.0 2.9e-05 24.8 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 EAQ89905.1 - 0.00046 19.8 0.0 0.0007 19.2 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 EAQ89905.1 - 0.002 17.8 1.0 0.039 13.6 1.0 2.6 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 EAQ89905.1 - 0.055 13.3 0.0 0.18 11.6 0.0 1.7 1 1 1 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 EAQ89905.1 - 0.093 12.5 0.1 0.17 11.7 0.1 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family AXE1 PF05448.12 EAQ89905.1 - 0.12 11.0 0.0 0.21 10.2 0.0 1.4 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) DUF2920 PF11144.8 EAQ89905.1 - 0.22 10.7 0.0 0.52 9.4 0.0 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2920) LigB PF02900.18 EAQ89906.1 - 1.3e-39 136.0 0.0 1.5e-39 135.8 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase TPR_11 PF13414.6 EAQ89906.1 - 0.088 12.5 0.2 0.24 11.1 0.0 1.8 2 0 0 2 2 2 0 TPR repeat TRI12 PF06609.13 EAQ89907.1 - 4.1e-30 104.8 27.8 5e-30 104.5 27.8 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 EAQ89907.1 - 6.3e-17 61.5 52.9 6.3e-17 61.5 52.9 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EAQ89907.1 - 2.7e-09 36.4 14.1 2.7e-09 36.4 14.1 2.5 2 0 0 2 2 2 1 Sugar (and other) transporter Ferric_reduct PF01794.19 EAQ89908.1 - 1.2e-17 64.2 2.9 3.4e-17 62.7 2.9 1.8 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 EAQ89908.1 - 5.1e-14 52.7 0.0 3.4e-09 37.0 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EAQ89908.1 - 4.4e-12 46.1 0.0 1.1e-11 44.7 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 EAQ89908.1 - 0.0015 19.1 0.0 0.19 12.4 0.0 2.4 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain DUF4405 PF14358.6 EAQ89908.1 - 0.25 11.9 3.2 0.85 10.2 0.5 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4405) AIM3 PF17096.5 EAQ89908.1 - 0.34 11.9 4.3 0.3 12.1 1.0 2.2 2 0 0 2 2 2 0 Altered inheritance of mitochondria protein 3 DAO PF01266.24 EAQ89909.1 - 1.1e-46 160.1 0.6 1.2e-46 159.9 0.6 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EAQ89909.1 - 0.00011 22.7 0.0 0.052 14.1 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EAQ89909.1 - 0.0014 18.8 0.0 0.0069 16.6 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EAQ89909.1 - 0.017 14.4 0.0 0.24 10.6 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EAQ89909.1 - 0.025 14.6 0.0 0.062 13.3 0.0 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding Trp_halogenase PF04820.14 EAQ89909.1 - 0.12 11.2 0.0 11 4.7 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Sacchrp_dh_NADP PF03435.18 EAQ89909.1 - 0.21 11.9 0.0 0.43 10.8 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain adh_short PF00106.25 EAQ89910.1 - 7.5e-39 133.2 0.9 2.3e-36 125.1 0.9 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EAQ89910.1 - 7e-31 107.6 0.3 1.5e-14 54.2 0.0 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EAQ89910.1 - 2.4e-08 34.1 2.2 2.7e-06 27.4 0.1 2.2 1 1 1 2 2 2 2 KR domain NAD_binding_10 PF13460.6 EAQ89910.1 - 0.00045 20.2 0.8 0.0018 18.2 0.1 2.0 2 1 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 EAQ89910.1 - 0.0018 17.8 0.1 0.023 14.2 0.0 2.3 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.17 EAQ89910.1 - 0.0046 17.5 0.4 0.017 15.7 0.0 2.1 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.18 EAQ89910.1 - 0.0098 16.1 0.1 0.029 14.6 0.0 1.8 2 0 0 2 2 2 1 TrkA-N domain ADH_zinc_N PF00107.26 EAQ89910.1 - 0.057 13.4 0.1 0.15 12.0 0.0 1.9 2 0 0 2 2 2 0 Zinc-binding dehydrogenase FmrO PF07091.11 EAQ89910.1 - 0.063 12.8 0.1 0.13 11.8 0.1 1.5 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) CBFD_NFYB_HMF PF00808.23 EAQ89911.1 - 1.3e-13 51.0 0.8 2.8e-13 50.0 0.8 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EAQ89911.1 - 0.00045 20.6 0.1 0.00099 19.5 0.1 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Spidroin_MaSp PF11260.8 EAQ89911.1 - 0.12 12.7 0.2 0.25 11.7 0.2 1.5 1 0 0 1 1 1 0 Major ampullate spidroin 1 and 2 DHHC PF01529.20 EAQ89913.1 - 1.4e-36 125.6 4.8 1.4e-36 125.6 4.8 1.9 2 1 0 2 2 2 1 DHHC palmitoyltransferase Yip1 PF04893.17 EAQ89913.1 - 0.0039 16.9 0.8 0.0039 16.9 0.8 2.1 2 0 0 2 2 2 1 Yip1 domain FAM199X PF15814.5 EAQ89913.1 - 2.8 6.9 5.3 4.2 6.3 5.3 1.2 1 0 0 1 1 1 0 Protein family FAM199X Complex1_LYR PF05347.15 EAQ89914.1 - 6.5e-16 58.1 0.9 1.2e-15 57.3 0.9 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Fungal_trans PF04082.18 EAQ89915.1 - 8.1e-08 31.6 0.4 1.7e-07 30.5 0.4 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EAQ89915.1 - 0.0027 17.8 7.8 0.0044 17.1 7.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HEAT PF02985.22 EAQ89917.1 - 2.6e-15 55.2 5.8 0.00055 20.0 0.0 9.0 9 0 0 9 9 8 2 HEAT repeat HEAT_EZ PF13513.6 EAQ89917.1 - 6e-12 45.8 8.9 3.8e-08 33.7 0.0 7.6 9 0 0 9 9 9 1 HEAT-like repeat HEAT_2 PF13646.6 EAQ89917.1 - 1.3e-08 35.1 13.0 0.76 10.2 0.0 7.4 6 2 2 8 8 7 3 HEAT repeats IBN_N PF03810.19 EAQ89917.1 - 1.9e-08 34.1 5.4 1.3e-07 31.5 1.6 3.9 4 0 0 4 4 4 1 Importin-beta N-terminal domain Arm PF00514.23 EAQ89917.1 - 0.0015 18.5 0.8 2.1 8.5 0.0 5.1 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat DUF3385 PF11865.8 EAQ89917.1 - 0.007 16.3 0.3 8.1 6.3 0.0 4.3 3 2 1 4 4 4 2 Domain of unknown function (DUF3385) Cnd1 PF12717.7 EAQ89917.1 - 0.0081 16.2 0.1 0.29 11.2 0.0 3.3 3 1 1 5 5 5 1 non-SMC mitotic condensation complex subunit 1 Cse1 PF08506.10 EAQ89917.1 - 0.027 13.3 0.0 1 8.1 0.0 2.9 3 0 0 3 3 3 0 Cse1 CLASP_N PF12348.8 EAQ89917.1 - 0.049 13.2 3.0 10 5.6 0.1 4.6 3 3 3 6 6 6 0 CLASP N terminal HEAT_PBS PF03130.16 EAQ89917.1 - 0.068 13.9 1.0 89 4.2 0.0 5.1 4 0 0 4 4 3 0 PBS lyase HEAT-like repeat PI3Ka PF00613.20 EAQ89917.1 - 0.076 12.4 0.0 1.2 8.5 0.0 2.8 4 0 0 4 4 4 0 Phosphoinositide 3-kinase family, accessory domain (PIK domain) HMGL-like PF00682.19 EAQ89918.1 - 1.8e-76 257.2 0.0 2.7e-76 256.6 0.0 1.3 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 EAQ89918.1 - 7.7e-15 55.0 0.1 7.9e-14 51.7 0.1 2.4 1 1 1 2 2 2 1 LeuA allosteric (dimerisation) domain Ferric_reduct PF01794.19 EAQ89919.1 - 1.6e-22 79.9 11.3 2.2e-22 79.5 7.7 2.5 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 EAQ89919.1 - 1.4e-17 64.2 0.0 1.7e-15 57.5 0.0 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EAQ89919.1 - 1.3e-09 38.1 0.0 4.1e-06 26.8 0.0 2.3 2 0 0 2 2 2 2 FAD-binding domain TcpE PF12648.7 EAQ89919.1 - 3.5 8.2 7.6 9.3 6.8 1.2 3.2 3 0 0 3 3 3 0 TcpE family DUF1690 PF07956.11 EAQ89921.1 - 1.3e-44 152.0 8.3 1.5e-44 151.8 8.3 1.0 1 0 0 1 1 1 1 Protein of Unknown function (DUF1690) AAA_13 PF13166.6 EAQ89921.1 - 0.0013 17.5 3.5 0.0016 17.2 3.5 1.1 1 0 0 1 1 1 1 AAA domain DUF885 PF05960.11 EAQ89921.1 - 0.045 13.4 3.4 0.054 13.1 3.4 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) FUSC PF04632.12 EAQ89921.1 - 0.52 8.8 5.7 0.62 8.5 5.7 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family HSCB_C PF07743.13 EAQ89921.1 - 1.7 9.2 11.6 1.5 9.3 3.4 2.8 2 1 1 3 3 3 0 HSCB C-terminal oligomerisation domain DUF4407 PF14362.6 EAQ89921.1 - 2.2 7.6 8.7 2.5 7.4 8.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) OmpH PF03938.14 EAQ89921.1 - 3.1 8.1 9.6 6.3 7.1 9.6 1.6 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) TYW3 PF02676.14 EAQ89922.1 - 9.3e-72 240.8 0.0 1.3e-71 240.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase TYW3 Fasciclin PF02469.22 EAQ89922.1 - 2.2e-40 137.8 0.5 7.2e-22 78.0 0.0 2.4 2 0 0 2 2 2 2 Fasciclin domain PAPS_reduct PF01507.19 EAQ89923.1 - 8e-43 146.5 0.0 1e-42 146.1 0.0 1.1 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Hydrolase_3 PF08282.12 EAQ89924.1 - 2.3e-09 37.4 0.4 2e-08 34.3 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EAQ89924.1 - 1.2e-07 32.3 2.9 7.1e-05 23.2 0.5 2.2 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 EAQ89924.1 - 5.2e-05 23.7 0.3 0.046 14.1 0.0 2.3 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EAQ89924.1 - 0.0063 16.6 0.3 0.17 12.0 0.0 2.4 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase DUF705 PF05152.12 EAQ89924.1 - 0.0098 15.4 0.0 0.014 14.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF705) S6PP PF05116.13 EAQ89924.1 - 0.029 13.9 0.1 0.17 11.4 0.0 1.9 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase Put_Phosphatase PF06888.12 EAQ89924.1 - 0.064 12.6 0.1 3.1 7.1 0.0 2.2 2 0 0 2 2 2 0 Putative Phosphatase Acid_PPase PF12689.7 EAQ89924.1 - 0.18 11.6 0.1 0.34 10.7 0.1 1.4 1 1 0 1 1 1 0 Acid Phosphatase GTP_EFTU PF00009.27 EAQ89925.1 - 3e-54 183.5 0.0 4.2e-54 183.0 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EAQ89925.1 - 7.6e-42 142.2 0.0 1.7e-41 141.1 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EAQ89925.1 - 5.4e-16 58.7 2.2 1.7e-15 57.1 1.0 2.5 3 0 0 3 3 3 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EAQ89925.1 - 0.00084 19.4 0.1 0.018 15.1 0.1 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 EAQ89925.1 - 0.047 13.6 0.4 0.14 12.1 0.4 1.8 1 0 0 1 1 1 0 Elongation factor Tu domain 4 SLS PF14611.6 EAQ89926.1 - 5.7e-35 121.1 0.3 1e-34 120.3 0.3 1.4 1 0 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator Trypan_PARP PF05887.11 EAQ89926.1 - 0.67 9.9 12.2 0.2 11.7 8.5 1.9 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Neisseria_TspB PF05616.13 EAQ89926.1 - 1.4 7.3 4.5 2.8 6.3 4.5 1.4 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein MAGE PF01454.19 EAQ89927.1 - 9.8e-63 211.7 0.0 1.3e-62 211.3 0.0 1.2 1 0 0 1 1 1 1 MAGE family FXR_C1 PF16096.5 EAQ89927.1 - 0.046 13.9 4.2 0.33 11.2 2.2 2.8 2 0 0 2 2 2 0 Fragile X-related 1 protein C-terminal region 2 MCM6_C PF18263.1 EAQ89927.1 - 0.046 13.9 0.0 1.3 9.2 0.0 2.4 2 0 0 2 2 2 0 MCM6 C-terminal winged-helix domain GFRP PF06399.13 EAQ89927.1 - 0.11 12.4 0.0 0.27 11.2 0.0 1.7 1 0 0 1 1 1 0 GTP cyclohydrolase I feedback regulatory protein (GFRP) SF3b10 PF07189.11 EAQ89928.1 - 5.7e-34 116.1 0.0 7.3e-32 109.3 0.0 2.1 2 0 0 2 2 2 2 Splicing factor 3B subunit 10 (SF3b10) zf-MYND PF01753.18 EAQ89929.1 - 0.00027 20.9 12.8 0.047 13.8 4.7 3.1 3 0 0 3 3 3 2 MYND finger PLATZ PF04640.14 EAQ89929.1 - 0.17 12.6 12.4 0.3 11.7 3.0 3.3 3 1 0 3 3 3 0 PLATZ transcription factor zf-C6H2 PF15801.5 EAQ89929.1 - 0.19 12.0 15.7 0.81 10.1 0.6 3.1 3 0 0 3 3 3 0 zf-MYND-like zinc finger, mRNA-binding Septin PF00735.18 EAQ89930.1 - 1.4e-32 113.2 0.1 3.3e-11 43.0 0.0 3.1 3 0 0 3 3 3 3 Septin G-alpha PF00503.20 EAQ89930.1 - 0.0062 15.7 0.0 0.014 14.6 0.0 1.5 2 0 0 2 2 2 1 G-protein alpha subunit FtsK_SpoIIIE PF01580.18 EAQ89930.1 - 0.014 14.7 0.0 0.026 13.9 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_18 PF13238.6 EAQ89930.1 - 0.015 15.9 0.0 0.78 10.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 EAQ89930.1 - 0.019 15.5 0.0 0.037 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 EAQ89930.1 - 0.019 15.0 0.1 0.073 13.2 0.0 2.0 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_15 PF13175.6 EAQ89930.1 - 0.036 13.8 0.0 0.055 13.2 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Pox_A32 PF04665.12 EAQ89930.1 - 0.067 12.6 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein GTP_EFTU PF00009.27 EAQ89930.1 - 0.096 12.2 0.0 9.9 5.6 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain SRPRB PF09439.10 EAQ89930.1 - 0.11 11.9 0.1 0.43 10.0 0.0 1.9 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Dynamin_N PF00350.23 EAQ89930.1 - 0.22 11.5 0.8 0.69 9.9 0.1 2.1 2 0 0 2 2 2 0 Dynamin family ABC1 PF03109.16 EAQ89932.1 - 4.9e-09 36.4 0.0 2.9e-08 33.9 0.0 2.2 2 0 0 2 2 2 1 ABC1 family SUR7 PF06687.12 EAQ89933.1 - 7.7e-17 61.6 8.1 7.7e-17 61.6 8.1 1.9 2 0 0 2 2 2 1 SUR7/PalI family DUF2678 PF10856.8 EAQ89933.1 - 0.57 10.1 3.0 1.2 9.1 3.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2678) 7TMR-DISM_7TM PF07695.11 EAQ89933.1 - 4 7.3 16.7 0.49 10.3 11.0 1.9 2 0 0 2 2 2 0 7TM diverse intracellular signalling bZIP_1 PF00170.21 EAQ89935.1 - 4.5e-08 33.1 16.1 8.5e-08 32.2 16.1 1.4 1 0 0 1 1 1 1 bZIP transcription factor PAP1 PF08601.10 EAQ89935.1 - 0.0003 20.6 11.4 0.0009 19.1 0.0 2.6 2 1 0 3 3 3 1 Transcription factor PAP1 Adaptin_binding PF10199.9 EAQ89935.1 - 0.0011 19.6 1.3 0.0015 19.1 1.3 1.3 1 0 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 SHE3 PF17078.5 EAQ89935.1 - 0.0091 15.7 10.1 0.012 15.3 10.1 1.1 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 V_ATPase_I PF01496.19 EAQ89935.1 - 0.011 13.8 2.3 0.013 13.5 2.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family bZIP_2 PF07716.15 EAQ89935.1 - 0.052 13.6 19.5 0.47 10.6 17.7 2.4 1 1 1 2 2 2 0 Basic region leucine zipper bZIP_Maf PF03131.17 EAQ89935.1 - 0.075 13.6 14.9 0.11 13.0 14.9 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor GvpL_GvpF PF06386.11 EAQ89935.1 - 0.13 12.1 7.2 0.22 11.4 7.2 1.3 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF GIT_CC PF16559.5 EAQ89935.1 - 0.15 11.9 2.6 0.32 10.9 2.6 1.5 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor ADIP PF11559.8 EAQ89935.1 - 0.19 11.8 12.9 7 6.7 14.7 2.0 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Vac_Fusion PF02346.16 EAQ89935.1 - 0.29 10.8 1.6 0.52 10.0 1.6 1.3 1 0 0 1 1 1 0 Chordopoxvirus multifunctional envelope protein A27 XhlA PF10779.9 EAQ89935.1 - 0.3 11.3 5.4 0.56 10.4 5.4 1.4 1 0 0 1 1 1 0 Haemolysin XhlA Herpes_UL25 PF01499.16 EAQ89935.1 - 0.34 9.4 5.4 0.48 8.9 5.4 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family DUF3584 PF12128.8 EAQ89935.1 - 0.95 6.9 11.2 1.3 6.5 11.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF4554 PF15091.6 EAQ89935.1 - 1.1 8.1 3.8 1.3 7.8 3.2 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4554) PA26 PF04636.13 EAQ89935.1 - 1.2 8.0 3.8 1.6 7.6 3.8 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) SVIP PF15811.5 EAQ89935.1 - 4.7 7.7 15.1 14 6.2 13.4 2.4 2 1 0 2 2 2 0 Small VCP/p97-interacting protein CDP-OH_P_transf PF01066.21 EAQ89936.1 - 2.4e-17 63.4 0.1 2.4e-17 63.4 0.1 3.4 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DUF3592 PF12158.8 EAQ89936.1 - 1.4 8.9 7.1 4.9 7.2 0.0 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3592) Adaptin_N PF01602.20 EAQ89937.1 - 2.6e-117 392.6 1.9 3.3e-117 392.2 1.9 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 EAQ89937.1 - 1.5e-55 187.5 4.5 3e-55 186.5 4.5 1.5 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 EAQ89937.1 - 7.3e-36 122.8 0.2 2.1e-35 121.3 0.2 1.9 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 EAQ89937.1 - 1.8e-17 63.5 1.0 2.3e-12 47.1 0.1 5.3 3 1 2 5 5 5 1 HEAT repeats Cnd1 PF12717.7 EAQ89937.1 - 1.6e-07 31.5 9.6 0.027 14.5 0.1 5.0 4 1 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT_PBS PF03130.16 EAQ89937.1 - 0.00024 21.5 0.2 1.2 10.0 0.0 4.7 4 0 0 4 4 4 1 PBS lyase HEAT-like repeat CLASP_N PF12348.8 EAQ89937.1 - 0.0024 17.5 3.0 0.017 14.7 0.1 3.0 3 1 1 4 4 4 1 CLASP N terminal RTP1_C1 PF10363.9 EAQ89937.1 - 0.015 15.5 0.9 2.2 8.5 0.0 3.6 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 Coatomer_b_Cpla PF14806.6 EAQ89937.1 - 0.028 14.4 0.0 0.18 11.8 0.0 2.3 2 0 0 2 2 2 0 Coatomer beta subunit appendage platform HEAT PF02985.22 EAQ89937.1 - 0.049 13.9 7.9 2.1 8.8 0.2 5.1 5 0 0 5 5 4 0 HEAT repeat DUF5010 PF16402.5 EAQ89937.1 - 0.066 12.0 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5010) HEAT_EZ PF13513.6 EAQ89937.1 - 0.78 10.3 2.5 2.5 8.7 0.7 2.9 2 0 0 2 2 2 0 HEAT-like repeat Myb_DNA-bind_6 PF13921.6 EAQ89938.1 - 0.12 12.7 0.1 0.36 11.1 0.1 1.8 2 0 0 2 2 2 0 Myb-like DNA-binding domain UPF0016 PF01169.19 EAQ89939.1 - 5.5e-42 142.0 26.0 2e-21 76.1 10.6 2.3 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 DUF2070 PF09843.9 EAQ89939.1 - 0.048 12.0 0.1 0.087 11.1 0.1 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) CENP-B_dimeris PF09026.10 EAQ89941.1 - 0.13 12.7 12.2 0.34 11.3 12.2 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain ATP-sulfurylase PF01747.17 EAQ89942.1 - 9.2e-88 293.2 0.0 1.4e-87 292.7 0.0 1.3 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.20 EAQ89942.1 - 1.8e-58 196.9 0.0 2.7e-58 196.3 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.6 EAQ89942.1 - 2.5e-53 180.0 0.0 3.9e-53 179.4 0.0 1.3 1 0 0 1 1 1 1 PUA-like domain AAA_18 PF13238.6 EAQ89942.1 - 0.096 13.2 0.0 0.18 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain TRP PF06011.12 EAQ89944.1 - 7.4e-99 331.4 11.7 8.9e-99 331.1 11.7 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 EAQ89944.1 - 3.9e-26 92.1 0.0 5.8e-26 91.5 0.0 1.3 1 0 0 1 1 1 1 ML-like domain Glycophorin_A PF01102.18 EAQ89944.1 - 0.077 13.2 0.2 1.3 9.2 0.0 2.5 2 0 0 2 2 2 0 Glycophorin A Dioxygenase_C PF00775.21 EAQ89945.1 - 4e-34 117.6 0.0 5.4e-34 117.2 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 EAQ89945.1 - 5.7e-30 103.0 0.0 8.3e-30 102.5 0.0 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 EAQ89945.1 - 3.5e-05 24.0 0.0 0.00014 22.1 0.0 2.0 1 1 0 1 1 1 1 Carboxypeptidase regulatory-like domain DUF824 PF05688.11 EAQ89945.1 - 0.044 13.6 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 Salmonella repeat of unknown function (DUF824) Big_1 PF02369.16 EAQ89945.1 - 0.064 13.3 0.2 0.27 11.3 0.2 2.1 1 1 0 1 1 1 0 Bacterial Ig-like domain (group 1) SpaA PF17802.1 EAQ89945.1 - 0.19 12.1 0.0 0.34 11.3 0.0 1.4 1 0 0 1 1 1 0 Prealbumin-like fold domain AdoMet_MTase PF07757.13 EAQ89946.1 - 1.7e-38 131.4 0.0 2.9e-38 130.7 0.0 1.3 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_32 PF13679.6 EAQ89946.1 - 0.084 12.9 0.2 1 9.4 0.2 2.4 1 1 0 1 1 1 0 Methyltransferase domain SUI1 PF01253.22 EAQ89947.1 - 2.1e-26 92.3 1.5 3.1e-26 91.7 1.5 1.2 1 0 0 1 1 1 1 Translation initiation factor SUI1 DUF2575 PF10837.8 EAQ89947.1 - 0.095 13.0 0.0 0.16 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2575) Ocnus PF05005.15 EAQ89947.1 - 0.097 12.8 1.0 0.11 12.6 0.4 1.4 2 0 0 2 2 2 0 Janus/Ocnus family (Ocnus) EOS1 PF12326.8 EAQ89948.1 - 1.3e-15 57.7 3.0 1.3e-15 57.7 3.0 2.2 1 1 1 2 2 2 2 N-glycosylation protein SSF PF00474.17 EAQ89949.1 - 1.3e-10 40.7 22.2 5.2e-10 38.8 22.2 1.8 1 1 0 1 1 1 1 Sodium:solute symporter family TMEM100 PF16311.5 EAQ89949.1 - 1.3 8.6 3.9 14 5.3 0.0 3.2 2 1 1 3 3 3 0 Transmembrane protein 100 RRM_1 PF00076.22 EAQ89950.1 - 2.5e-25 88.1 0.1 1.4e-15 56.9 0.0 3.5 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EAQ89950.1 - 0.07 13.2 0.0 7.5 6.7 0.0 2.6 2 0 0 2 2 2 0 RNA recognition motif CIA30 PF08547.12 EAQ89952.1 - 1.4e-48 165.0 0.0 1.9e-48 164.5 0.0 1.2 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) YflT PF11181.8 EAQ89953.1 - 0.054 14.0 0.2 0.14 12.7 0.2 1.6 1 0 0 1 1 1 0 Heat induced stress protein YflT JmjC PF02373.22 EAQ89954.1 - 2.4e-16 60.1 0.0 4.6e-16 59.3 0.0 1.4 1 0 0 1 1 1 1 JmjC domain, hydroxylase SET PF00856.28 EAQ89954.1 - 3.4e-07 30.8 0.0 8.1e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 SET domain OmpH PF03938.14 EAQ89955.1 - 0.0058 17.0 0.3 0.013 15.8 0.2 1.5 1 1 1 2 2 2 1 Outer membrane protein (OmpH-like) BLOC1_2 PF10046.9 EAQ89955.1 - 0.029 14.7 0.3 0.056 13.7 0.3 1.4 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 AIP3 PF03915.13 EAQ89955.1 - 0.034 13.2 0.1 0.051 12.7 0.1 1.2 1 0 0 1 1 1 0 Actin interacting protein 3 TPR_MLP1_2 PF07926.12 EAQ89955.1 - 0.036 14.1 2.7 0.18 11.9 2.7 2.0 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein FAM184 PF15665.5 EAQ89955.1 - 0.054 13.3 0.1 0.073 12.8 0.1 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B ATG16 PF08614.11 EAQ89955.1 - 0.083 13.1 0.2 0.083 13.1 0.2 2.0 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) V-ATPase_G_2 PF16999.5 EAQ89955.1 - 0.19 12.1 8.6 0.18 12.3 6.8 1.7 1 1 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit CLZ PF16526.5 EAQ89955.1 - 0.23 11.8 1.0 0.94 9.9 0.3 2.2 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ABC_tran_CTD PF16326.5 EAQ89955.1 - 2 8.7 7.4 8.1 6.8 0.2 3.1 2 1 1 3 3 3 0 ABC transporter C-terminal domain HSCB_C PF07743.13 EAQ89955.1 - 3.2 8.3 6.3 1.2 9.6 3.0 2.0 2 1 0 2 2 2 0 HSCB C-terminal oligomerisation domain Thioredoxin PF00085.20 EAQ89956.1 - 1.1e-05 25.3 0.0 1.7e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin DUF953 PF06110.11 EAQ89956.1 - 0.054 13.1 0.1 0.52 9.9 0.1 2.1 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) Redoxin PF08534.10 EAQ89956.1 - 0.096 12.4 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Redoxin MFS_1 PF07690.16 EAQ89957.1 - 4.5e-43 147.5 30.5 4.1e-31 108.2 11.2 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.24 EAQ89957.1 - 1.1e-13 50.9 9.0 1.1e-13 50.9 9.0 2.7 2 1 0 2 2 2 1 Sugar (and other) transporter DUF4231 PF14015.6 EAQ89957.1 - 6.2 7.4 5.6 1.3 9.5 0.5 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) ELP6 PF09807.9 EAQ89958.1 - 5e-05 22.8 0.0 0.00018 21.0 0.1 1.7 2 0 0 2 2 2 1 Elongation complex protein 6 Ribosomal_L37e PF01907.19 EAQ89959.1 - 3e-26 91.3 12.5 4.2e-26 90.8 12.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.7 EAQ89959.1 - 0.017 15.1 1.3 0.026 14.6 1.3 1.2 1 0 0 1 1 1 0 Double zinc ribbon zf-C3HC4_2 PF13923.6 EAQ89959.1 - 0.43 10.5 2.8 0.71 9.8 2.8 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF1289 PF06945.13 EAQ89959.1 - 2.2 8.1 8.6 0.67 9.8 0.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1289) tRNA-synt_1 PF00133.22 EAQ89960.1 - 3.9e-229 761.9 0.0 7.7e-228 757.6 0.0 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EAQ89960.1 - 1.7e-35 122.3 0.0 4.9e-35 120.7 0.0 1.8 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 EAQ89960.1 - 5.2e-15 55.1 0.5 0.0002 20.3 0.1 4.5 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 EAQ89960.1 - 1.1e-10 41.4 0.1 1.7e-07 31.0 0.0 2.8 2 1 1 3 3 3 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 EAQ89960.1 - 0.0044 16.4 0.0 0.031 13.6 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain zf-RING_2 PF13639.6 EAQ89961.1 - 1.4e-12 47.7 5.1 2.3e-12 47.1 5.1 1.3 1 0 0 1 1 1 1 Ring finger domain PA PF02225.22 EAQ89961.1 - 3.3e-10 39.9 0.0 9.1e-10 38.4 0.0 1.7 1 0 0 1 1 1 1 PA domain zf-C3HC4_2 PF13923.6 EAQ89961.1 - 2.7e-09 36.7 4.3 4.3e-09 36.1 4.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EAQ89961.1 - 1.6e-08 34.7 3.9 3.2e-08 33.7 3.9 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EAQ89961.1 - 1.7e-08 34.2 3.5 2.8e-08 33.5 3.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EAQ89961.1 - 5.6e-08 32.4 2.5 5.6e-08 32.4 2.5 2.0 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_5 PF14634.6 EAQ89961.1 - 4.6e-07 29.7 3.2 7.1e-07 29.1 3.2 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EAQ89961.1 - 4.6e-06 26.5 2.0 1.1e-05 25.3 0.4 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EAQ89961.1 - 8.6e-06 25.5 3.5 1.3e-05 24.9 3.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EAQ89961.1 - 0.0013 18.7 2.6 0.0038 17.2 2.6 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 EAQ89961.1 - 0.0024 17.7 3.2 0.0045 16.8 3.2 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 EAQ89961.1 - 0.015 15.5 4.4 0.17 12.1 4.7 2.2 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 EAQ89961.1 - 0.072 13.3 3.0 0.24 11.6 3.0 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 EAQ89961.1 - 0.15 11.7 3.8 0.29 10.8 3.8 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Cys_Knot_tox PF17486.2 EAQ89961.1 - 0.39 11.0 1.7 0.63 10.3 0.1 2.0 2 0 0 2 2 2 0 Cystine knot toxins RINGv PF12906.7 EAQ89961.1 - 0.74 10.0 4.8 1.1 9.4 3.9 1.8 1 1 1 2 2 2 0 RING-variant domain zf-RING_4 PF14570.6 EAQ89961.1 - 0.75 9.6 2.8 1.3 8.9 2.8 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.29 EAQ89961.1 - 0.96 9.4 3.3 2 8.4 3.3 1.5 1 0 0 1 1 1 0 PHD-finger zf-Nse PF11789.8 EAQ89961.1 - 1 9.3 2.8 2.1 8.3 2.8 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING-like PF08746.11 EAQ89961.1 - 1.5 9.2 3.3 2.7 8.4 3.3 1.4 1 0 0 1 1 1 0 RING-like domain ANAPC5 PF12862.7 EAQ89962.1 - 1.2e-29 102.2 4.4 2.2e-29 101.4 0.8 2.8 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 5 TPR_10 PF13374.6 EAQ89962.1 - 0.0024 17.7 0.2 2.5 8.1 0.0 3.3 2 0 0 2 2 2 2 Tetratricopeptide repeat COX6A PF02046.15 EAQ89963.1 - 7.1e-44 148.8 2.1 8.6e-44 148.6 2.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa DUF2933 PF11666.8 EAQ89963.1 - 0.086 12.9 0.2 0.14 12.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2933) FtsK_SpoIIIE_N PF12538.8 EAQ89963.1 - 0.14 12.4 0.0 0.19 11.9 0.0 1.2 1 0 0 1 1 1 0 DNA transporter Exo_endo_phos PF03372.23 EAQ89964.1 - 4.7e-12 45.9 0.0 8e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-GRF PF06839.12 EAQ89964.1 - 2.8e-05 24.1 1.8 7.1e-05 22.8 1.8 1.7 1 0 0 1 1 1 1 GRF zinc finger HMG_box PF00505.19 EAQ89965.1 - 7.6e-16 58.3 0.2 1.2e-15 57.7 0.2 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box MAT1-1-2 PF17043.5 EAQ89966.1 - 1.8e-38 131.8 0.1 3.9e-38 130.8 0.1 1.5 1 0 0 1 1 1 1 Mating type protein 1-1-2 of unknown function MATalpha_HMGbox PF04769.12 EAQ89967.1 - 8e-72 240.8 0.0 1e-71 240.4 0.0 1.1 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 HMG-box ANTH PF07651.16 EAQ89968.1 - 1.5e-79 266.9 1.1 3.4e-79 265.7 0.0 2.1 2 1 0 2 2 2 1 ANTH domain I_LWEQ PF01608.17 EAQ89968.1 - 4e-55 186.3 8.3 4e-55 186.3 8.3 4.7 4 1 2 6 6 5 1 I/LWEQ domain FAM184 PF15665.5 EAQ89968.1 - 0.0055 16.5 16.7 0.0055 16.5 16.7 3.8 2 1 1 3 3 3 2 Family with sequence similarity 184, A and B Surfac_D-trimer PF09006.11 EAQ89968.1 - 0.017 15.0 2.3 0.017 15.0 2.3 2.7 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation TP6A_N PF04406.14 EAQ89968.1 - 0.064 13.2 0.2 28 4.8 0.0 3.2 3 0 0 3 3 3 0 Type IIB DNA topoisomerase HAUS-augmin3 PF14932.6 EAQ89968.1 - 0.075 12.6 34.5 0.2 11.2 7.0 3.7 2 1 1 3 3 3 0 HAUS augmin-like complex subunit 3 Phe_ZIP PF08916.11 EAQ89968.1 - 0.11 13.2 0.1 0.34 11.6 0.1 1.8 1 0 0 1 1 1 0 Phenylalanine zipper Abi_C PF14355.6 EAQ89968.1 - 0.49 10.5 3.4 25 5.0 0.0 4.4 4 1 0 4 4 4 0 Abortive infection C-terminus Spc7 PF08317.11 EAQ89968.1 - 2.2 7.1 43.1 0.019 13.9 13.2 4.1 3 1 1 4 4 4 0 Spc7 kinetochore protein FAA_hydro_N_2 PF18288.1 EAQ89968.1 - 3.3 8.2 7.1 1.2 9.6 0.9 3.7 3 1 1 4 4 4 0 Fumarylacetoacetase N-terminal domain 2 Lebercilin PF15619.6 EAQ89968.1 - 4.1 7.0 44.5 0.093 12.4 4.7 5.0 2 1 1 4 4 4 0 Ciliary protein causing Leber congenital amaurosis disease ATG16 PF08614.11 EAQ89968.1 - 4.7 7.4 55.2 1.7 8.8 8.4 4.5 2 1 2 4 4 4 0 Autophagy protein 16 (ATG16) Prominin PF05478.11 EAQ89968.1 - 7.2 4.4 23.5 0.1 10.5 2.8 2.8 3 1 0 3 3 3 0 Prominin Autophagy_N PF03986.13 EAQ89969.1 - 1.4e-44 151.4 0.2 2.4e-44 150.6 0.0 1.5 2 0 0 2 2 2 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.15 EAQ89969.1 - 4.6e-15 56.0 0.1 8.9e-15 55.0 0.1 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_C PF10381.9 EAQ89969.1 - 2.1e-06 27.2 0.6 7.6e-06 25.3 0.6 2.0 1 1 0 1 1 1 1 Autophagocytosis associated protein C-terminal zf-C3HC4_2 PF13923.6 EAQ89970.1 - 2.7e-08 33.5 6.7 4.7e-08 32.7 6.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EAQ89970.1 - 5e-08 32.7 4.6 8.4e-08 32.0 4.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EAQ89970.1 - 6.1e-08 32.6 4.4 1.2e-07 31.6 4.4 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EAQ89970.1 - 3e-07 30.2 7.6 5.3e-07 29.4 7.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EAQ89970.1 - 1.1e-06 28.5 6.8 1.8e-06 27.8 6.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-CCCH PF00642.24 EAQ89970.1 - 2.1e-06 27.5 1.7 4.5e-06 26.4 1.7 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-RING_2 PF13639.6 EAQ89970.1 - 6.5e-06 26.4 5.7 1.2e-05 25.6 5.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_10 PF16685.5 EAQ89970.1 - 1.5e-05 25.1 3.0 2.7e-05 24.2 3.0 1.4 1 0 0 1 1 1 1 zinc RING finger of MSL2 Prok-RING_4 PF14447.6 EAQ89970.1 - 0.0014 18.5 4.8 0.0025 17.6 4.8 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 EAQ89970.1 - 0.0014 18.7 7.3 0.0031 17.6 7.3 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf_CCCH_4 PF18345.1 EAQ89970.1 - 0.009 16.0 4.9 0.017 15.1 4.9 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 EAQ89970.1 - 0.032 14.0 2.7 0.075 12.9 2.7 1.7 1 0 0 1 1 1 0 CCCH-type zinc finger zf-CCCH_2 PF14608.6 EAQ89970.1 - 0.21 12.1 1.7 0.41 11.2 1.7 1.5 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger Harakiri PF15196.6 EAQ89970.1 - 0.25 11.8 3.4 0.31 11.5 1.8 2.0 2 0 0 2 2 2 0 Activator of apoptosis harakiri zf-RING_11 PF17123.5 EAQ89970.1 - 0.73 9.6 4.4 1.5 8.6 4.4 1.6 1 0 0 1 1 1 0 RING-like zinc finger Mcp5_PH PF12814.7 EAQ89971.1 - 5.1e-46 155.8 0.1 1.2e-45 154.5 0.1 1.7 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology PH PF00169.29 EAQ89971.1 - 1.5e-05 25.4 0.0 4.7e-05 23.9 0.0 1.9 1 0 0 1 1 1 1 PH domain Lectin_N PF03954.14 EAQ89971.1 - 2.4 7.9 8.5 0.43 10.3 2.5 2.6 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain Fez1 PF06818.15 EAQ89971.1 - 5.2 7.5 47.2 0.044 14.2 19.8 3.9 4 1 0 5 5 5 0 Fez1 DNA_pol_B PF00136.21 EAQ89973.1 - 1.9e-99 333.5 0.0 2.8e-99 332.9 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 EAQ89973.1 - 1e-21 77.5 0.0 1.2e-13 50.9 0.0 2.4 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 EAQ89973.1 - 2.4e-07 31.1 0.5 7.6e-07 29.5 0.5 1.9 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta XkdW PF09636.10 EAQ89973.1 - 0.054 13.6 0.3 0.19 11.8 0.3 1.9 1 0 0 1 1 1 0 XkdW protein DUF4538 PF15061.6 EAQ89973.1 - 0.27 11.0 0.7 0.8 9.5 0.7 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4538) Slu7 PF11708.8 EAQ89974.1 - 8.2e-69 232.3 13.5 1.2e-67 228.5 13.5 2.2 1 1 0 1 1 1 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.6 EAQ89974.1 - 0.0056 16.4 0.2 0.012 15.3 0.2 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 EAQ89974.1 - 0.036 14.2 4.5 0.067 13.3 4.5 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_6 PF15288.6 EAQ89974.1 - 0.06 13.2 4.1 0.16 11.8 4.1 1.7 1 0 0 1 1 1 0 Zinc knuckle S4 PF01479.25 EAQ89975.1 - 1.2e-12 47.3 1.5 1.2e-12 47.3 1.5 2.3 3 0 0 3 3 3 1 S4 domain Ribosomal_S4 PF00163.19 EAQ89975.1 - 1.6e-05 25.8 0.0 3.2e-05 24.7 0.0 1.6 1 1 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain Uds1 PF15456.6 EAQ89975.1 - 0.024 14.8 0.7 0.47 10.6 0.0 2.2 2 0 0 2 2 2 0 Up-regulated During Septation Ribosomal_L21e PF01157.18 EAQ89976.1 - 8e-47 157.2 5.8 1.4e-46 156.5 4.2 1.8 2 0 0 2 2 2 1 Ribosomal protein L21e MMM1 PF10296.9 EAQ89977.1 - 0.0011 18.0 0.0 0.0011 18.0 0.0 2.8 3 1 1 4 4 4 2 Maintenance of mitochondrial morphology protein 1 ISN1 PF06437.11 EAQ89980.1 - 5.1e-173 575.7 0.0 5.8e-173 575.5 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase Acyl-CoA_dh_2 PF08028.11 EAQ89981.1 - 0.25 11.6 2.0 0.57 10.4 2.0 1.6 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain Glycos_trans_3N PF02885.17 EAQ89982.1 - 0.096 12.5 0.4 0.12 12.2 0.4 1.2 1 0 0 1 1 1 0 Glycosyl transferase family, helical bundle domain Pkinase PF00069.25 EAQ89985.1 - 1.2e-50 172.3 0.0 1.7e-50 171.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ89985.1 - 9.9e-26 90.6 0.2 1.8e-24 86.4 0.2 2.4 2 1 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EAQ89985.1 - 0.0063 15.3 0.0 0.012 14.4 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 EAQ89985.1 - 0.014 15.0 0.4 3 7.4 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 EAQ89985.1 - 0.027 13.8 0.2 0.17 11.2 0.0 2.0 2 0 0 2 2 2 0 Kinase-like IBN_N PF03810.19 EAQ89986.1 - 4.2e-12 45.8 1.3 3.3e-09 36.5 0.0 3.3 3 0 0 3 3 3 2 Importin-beta N-terminal domain Cse1 PF08506.10 EAQ89986.1 - 8.2e-08 31.5 0.0 2.4e-07 30.0 0.0 1.8 1 0 0 1 1 1 1 Cse1 Xpo1 PF08389.12 EAQ89986.1 - 3.5e-06 27.1 2.0 0.00011 22.3 0.1 3.9 5 0 0 5 5 5 1 Exportin 1-like protein Importin_rep_6 PF18829.1 EAQ89986.1 - 0.031 14.4 0.1 0.12 12.5 0.1 2.1 1 0 0 1 1 1 0 Importin repeat 6 DUF2013 PF09431.10 EAQ89986.1 - 0.12 12.5 0.3 0.52 10.5 0.3 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2013) GRIP PF01465.20 EAQ89986.1 - 0.13 12.2 0.0 0.54 10.2 0.0 2.2 1 0 0 1 1 1 0 GRIP domain IMS PF00817.20 EAQ89989.1 - 3.7e-25 88.7 0.0 5e-24 85.0 0.0 2.5 1 1 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 EAQ89989.1 - 4.5e-15 56.4 0.0 8.9e-15 55.4 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain zf_UBZ PF18439.1 EAQ89989.1 - 6.2e-11 41.7 4.2 1.3e-10 40.7 4.2 1.5 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger IMS_HHH PF11798.8 EAQ89989.1 - 0.0062 16.8 0.0 0.013 15.8 0.0 1.6 1 0 0 1 1 1 1 IMS family HHH motif DHHC PF01529.20 EAQ89990.1 - 1.5e-16 60.7 28.8 4.6e-12 46.2 9.9 3.3 3 0 0 3 3 3 2 DHHC palmitoyltransferase Wzy_C PF04932.15 EAQ89990.1 - 0.09 12.4 1.6 0.2 11.3 0.2 2.0 2 0 0 2 2 2 0 O-Antigen ligase DUF1129 PF06570.11 EAQ89990.1 - 1.9 7.9 5.6 1.5 8.2 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) SET PF00856.28 EAQ89993.1 - 2.6e-15 57.2 1.1 2.6e-15 57.2 1.1 3.0 3 2 0 3 3 3 1 SET domain AWS PF17907.1 EAQ89993.1 - 7.6e-08 32.3 6.8 1.8e-07 31.0 6.8 1.6 1 0 0 1 1 1 1 AWS domain LSM PF01423.22 EAQ89994.1 - 3.6e-19 68.2 0.2 4.5e-19 67.9 0.2 1.1 1 0 0 1 1 1 1 LSM domain FoP_duplication PF13865.6 EAQ89994.1 - 2.3e-05 24.8 15.5 3.3e-05 24.3 15.5 1.3 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 Pan3_PK PF18101.1 EAQ89995.1 - 1.2e-51 174.3 0.0 1.8e-51 173.7 0.0 1.3 1 0 0 1 1 1 1 Pan3 Pseudokinase domain Pkinase PF00069.25 EAQ89995.1 - 0.00021 20.7 0.1 0.00036 20.0 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ89995.1 - 0.016 14.5 0.1 0.025 13.8 0.1 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase PAM2 PF07145.15 EAQ89995.1 - 2.1 8.2 8.1 17 5.4 0.2 3.6 3 0 0 3 3 3 0 Ataxin-2 C-terminal region UBA_4 PF14555.6 EAQ89996.1 - 1.5e-10 40.7 0.0 3.2e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.20 EAQ89996.1 - 0.00049 20.3 0.0 0.002 18.3 0.0 2.0 2 0 0 2 2 2 1 UBX domain DUF4449 PF14613.6 EAQ89996.1 - 0.69 10.0 3.4 1.9 8.6 3.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4449) GAT PF03127.14 EAQ89997.1 - 1.2e-16 60.8 0.6 1.9e-16 60.2 0.1 1.6 2 0 0 2 2 2 1 GAT domain VHS PF00790.19 EAQ89997.1 - 0.0026 17.6 0.0 0.0054 16.6 0.0 1.5 1 0 0 1 1 1 1 VHS domain SPX PF03105.19 EAQ89997.1 - 1.4 8.8 6.7 2 8.2 6.7 1.2 1 0 0 1 1 1 0 SPX domain Zn_clus PF00172.18 EAQ89999.1 - 8.2e-08 32.2 8.4 1.3e-07 31.6 8.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TFIIA PF03153.13 EAQ89999.1 - 3 7.7 19.7 0.12 12.3 14.2 1.5 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Methyltransf_23 PF13489.6 EAQ90004.1 - 7e-16 58.5 0.0 1.2e-15 57.8 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EAQ90004.1 - 1.6e-12 47.9 0.0 4.9e-12 46.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAQ90004.1 - 2.2e-12 47.0 0.0 2.4e-11 43.6 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAQ90004.1 - 6.1e-12 46.1 0.1 2.3e-11 44.2 0.0 2.1 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EAQ90004.1 - 7.4e-11 42.7 0.0 1.8e-10 41.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EAQ90004.1 - 1.8e-07 30.7 0.0 3.2e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 EAQ90004.1 - 0.00043 20.3 0.3 0.00092 19.2 0.0 1.7 2 1 0 2 2 2 1 Methyltransferase domain CMAS PF02353.20 EAQ90004.1 - 0.0048 16.2 0.0 0.0091 15.3 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase TPMT PF05724.11 EAQ90004.1 - 0.0072 16.0 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) MTS PF05175.14 EAQ90004.1 - 0.034 13.7 0.1 0.074 12.6 0.0 1.5 2 0 0 2 2 2 0 Methyltransferase small domain DREV PF05219.12 EAQ90004.1 - 0.16 11.0 0.0 0.25 10.4 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase His_Phos_1 PF00300.22 EAQ90005.1 - 4.1e-29 101.6 2.2 7.4e-27 94.3 2.2 2.5 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) MGC-24 PF05283.11 EAQ90006.1 - 0.074 13.5 7.9 0.12 12.8 7.9 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin GRIM-19 PF06212.12 EAQ90006.1 - 0.11 12.4 0.3 0.16 11.9 0.3 1.2 1 0 0 1 1 1 0 GRIM-19 protein Hamartin PF04388.12 EAQ90006.1 - 0.56 8.8 9.7 0.66 8.6 9.7 1.0 1 0 0 1 1 1 0 Hamartin protein Pex14_N PF04695.13 EAQ90006.1 - 0.76 10.4 11.5 0.96 10.1 6.7 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region UCH PF00443.29 EAQ90007.1 - 6.3e-51 173.3 0.0 9.9e-51 172.7 0.0 1.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EAQ90007.1 - 3.3e-14 53.2 6.9 1.9e-13 50.7 6.9 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 EAQ90007.1 - 4.7e-12 45.5 0.1 1.2e-11 44.2 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin family eIF-3c_N PF05470.12 EAQ90007.1 - 0.21 9.8 8.7 0.031 12.6 4.8 1.5 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Paramyxo_ncap PF00973.19 EAQ90007.1 - 1.2 8.0 4.5 1.8 7.4 4.5 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein ARPC4 PF05856.12 EAQ90008.1 - 2e-80 268.3 4.1 2.2e-80 268.1 4.1 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) Mito_carr PF00153.27 EAQ90010.1 - 2.6e-76 251.7 0.8 2.4e-25 88.3 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EAQ90010.1 - 0.0035 16.6 1.7 3 6.9 0.1 3.4 1 1 4 5 5 5 3 Gammaproteobacterial serine protease HMD PF03201.16 EAQ90010.1 - 0.13 12.5 0.0 1.7 8.9 0.0 2.7 3 1 1 4 4 4 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase PX PF00787.24 EAQ90011.1 - 1.2e-25 89.7 0.0 1.4e-25 89.5 0.0 1.0 1 0 0 1 1 1 1 PX domain PRP21_like_P PF12230.8 EAQ90012.1 - 5.2e-60 203.0 8.0 9.5e-60 202.2 8.0 1.4 1 0 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.20 EAQ90012.1 - 5.5e-37 125.5 0.8 1.7e-17 63.1 0.3 2.5 2 0 0 2 2 2 2 Surp module zf_UBZ PF18439.1 EAQ90012.1 - 0.0014 18.2 0.6 0.0026 17.3 0.6 1.5 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger Orbi_VP6 PF01516.16 EAQ90012.1 - 0.012 15.2 0.5 0.96 8.9 1.3 2.3 2 0 0 2 2 2 0 Orbivirus helicase VP6 zf_C2HC_14 PF18574.1 EAQ90012.1 - 0.13 12.1 0.2 0.24 11.2 0.2 1.4 1 0 0 1 1 1 0 C2HC Zing finger domain PMT PF02366.18 EAQ90013.1 - 1e-76 257.8 18.0 1.8e-76 256.9 18.0 1.4 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 EAQ90013.1 - 3.5e-67 225.9 9.1 3.5e-67 225.9 9.1 2.4 3 0 0 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 EAQ90013.1 - 1.6e-48 165.0 0.0 3e-48 164.1 0.0 1.4 1 0 0 1 1 1 1 MIR domain PPP4R2 PF09184.11 EAQ90014.1 - 0.24 10.9 13.9 0.46 10.0 13.9 1.3 1 0 0 1 1 1 0 PPP4R2 SDA1 PF05285.12 EAQ90014.1 - 7.6 5.9 23.6 13 5.1 23.6 1.3 1 0 0 1 1 1 0 SDA1 Sec2p PF06428.11 EAQ90015.1 - 3.8e-27 94.1 18.5 3.8e-27 94.1 18.5 2.4 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p DUF3584 PF12128.8 EAQ90015.1 - 1.1 6.6 23.6 1.7 6.0 23.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF5339 PF17274.2 EAQ90015.1 - 1.7 9.6 14.4 14 6.6 1.3 3.7 2 1 1 3 3 3 0 Family of unknown function (DUF5339) SNARE PF05739.19 EAQ90018.1 - 3.3e-14 52.6 0.7 1.3e-13 50.7 0.1 2.1 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.25 EAQ90018.1 - 0.001 18.8 2.9 0.0011 18.6 0.4 2.2 2 1 0 2 2 2 1 Syntaxin Peripla_BP_2 PF01497.18 EAQ90018.1 - 0.027 14.1 0.1 0.038 13.5 0.1 1.2 1 0 0 1 1 1 0 Periplasmic binding protein DUF1664 PF07889.12 EAQ90018.1 - 0.057 13.5 0.9 1.6 8.8 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) MCPsignal PF00015.21 EAQ90018.1 - 0.062 13.1 2.4 0.18 11.6 1.8 1.9 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain KxDL PF10241.9 EAQ90018.1 - 0.14 12.5 1.4 21 5.5 0.0 2.9 3 1 0 3 3 3 0 Uncharacterized conserved protein Prominin PF05478.11 EAQ90018.1 - 0.15 10.0 0.9 0.66 7.9 0.0 1.9 2 0 0 2 2 2 0 Prominin Muted PF14942.6 EAQ90018.1 - 0.15 12.4 4.4 2 8.8 0.4 2.2 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein NPV_P10 PF05531.12 EAQ90018.1 - 0.18 12.3 2.0 28 5.3 0.0 3.1 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein SlyX PF04102.12 EAQ90018.1 - 1 10.0 4.7 2.4 8.8 0.2 2.9 2 1 0 2 2 2 0 SlyX DUF16 PF01519.16 EAQ90018.1 - 1.2 9.7 4.8 0.47 11.0 0.9 2.0 2 0 0 2 2 2 0 Protein of unknown function DUF16 Aldo_ket_red PF00248.21 EAQ90019.1 - 2.3e-43 148.5 0.0 2.5e-41 141.8 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family ADH_N PF08240.12 EAQ90020.1 - 7.7e-28 96.6 0.8 1.7e-27 95.5 0.8 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EAQ90020.1 - 4.3e-16 59.1 0.1 9.3e-16 58.0 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EAQ90020.1 - 8.9e-08 31.9 0.2 0.0089 15.5 0.1 2.4 2 0 0 2 2 2 2 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 EAQ90020.1 - 0.0022 17.3 0.5 0.0042 16.4 0.5 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 EAQ90020.1 - 0.06 13.2 0.2 0.11 12.4 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 EAQ90020.1 - 0.082 12.5 0.2 0.14 11.7 0.2 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain adh_short_C2 PF13561.6 EAQ90021.1 - 1.9e-57 194.5 0.1 2.5e-57 194.2 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EAQ90021.1 - 4.3e-51 173.2 0.7 7.4e-51 172.4 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 EAQ90021.1 - 9.1e-15 55.0 0.3 2e-14 53.9 0.3 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EAQ90021.1 - 1.5e-07 31.1 0.0 1.9e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EAQ90021.1 - 0.0062 15.7 0.1 0.02 14.0 0.0 1.8 2 0 0 2 2 2 1 RmlD substrate binding domain Phytase-like PF13449.6 EAQ90021.1 - 0.066 13.2 0.1 0.093 12.7 0.1 1.2 1 0 0 1 1 1 0 Esterase-like activity of phytase GDP_Man_Dehyd PF16363.5 EAQ90021.1 - 0.15 11.4 0.2 0.31 10.4 0.1 1.6 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase DUF1100 PF06500.11 EAQ90022.1 - 1.3e-06 27.5 0.0 1.7e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Peptidase_S9 PF00326.21 EAQ90022.1 - 1.5e-06 27.8 0.0 3.1e-06 26.8 0.0 1.5 1 1 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 EAQ90022.1 - 3.4e-05 23.6 0.0 5.4e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.7 EAQ90022.1 - 0.0012 19.4 0.0 0.0031 18.1 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Esterase PF00756.20 EAQ90022.1 - 0.0014 18.3 0.0 0.0058 16.3 0.0 2.0 1 1 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 EAQ90022.1 - 0.0036 16.6 0.0 0.33 10.2 0.0 2.2 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Esterase_phd PF10503.9 EAQ90022.1 - 0.073 12.5 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 Esterase PHB depolymerase BAAT_C PF08840.11 EAQ90022.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Acetyltransf_1 PF00583.25 EAQ90023.1 - 6.7e-14 52.1 0.0 8.2e-14 51.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EAQ90023.1 - 2.2e-08 34.1 0.0 3e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EAQ90023.1 - 3e-08 34.0 0.1 4.2e-08 33.5 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain hnRNP_Q_AcD PF18360.1 EAQ90023.1 - 0.13 12.2 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Heterogeneous nuclear ribonucleoprotein Q acidic domain Glyco_hydro_43 PF04616.14 EAQ90024.1 - 5.2e-28 98.2 7.1 1.6e-26 93.3 7.1 2.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_68 PF02435.16 EAQ90024.1 - 0.023 13.5 0.8 1.3 7.7 0.0 3.0 2 2 1 3 3 3 0 Levansucrase/Invertase DUF3318 PF11780.8 EAQ90025.1 - 0.17 11.9 0.5 0.3 11.0 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3318) SKG6 PF08693.10 EAQ90025.1 - 0.24 10.8 2.8 0.48 9.9 2.8 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain SIT PF15330.6 EAQ90025.1 - 0.79 10.2 0.0 0.79 10.2 0.0 2.5 2 1 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT DUF2052 PF09747.9 EAQ90027.1 - 1.8e-26 93.5 1.9 3.3e-26 92.7 1.9 1.3 1 0 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) SSP160 PF06933.11 EAQ90027.1 - 2.9 6.0 7.3 3.8 5.6 7.3 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Mucin PF01456.17 EAQ90027.1 - 3.3 7.7 15.7 5.9 6.9 15.7 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF87 PF01935.17 EAQ90028.1 - 0.0011 19.1 0.2 0.016 15.3 0.0 2.4 2 1 0 2 2 2 1 Helicase HerA, central domain AAA_16 PF13191.6 EAQ90028.1 - 0.0047 17.3 0.0 0.64 10.4 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EAQ90028.1 - 0.006 16.9 0.0 0.29 11.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 EAQ90028.1 - 0.034 13.4 0.1 0.079 12.2 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin FtsK_SpoIIIE PF01580.18 EAQ90028.1 - 0.04 13.3 0.0 0.079 12.3 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family PknG_rubred PF16919.5 EAQ90028.1 - 0.12 12.6 0.5 0.24 11.6 0.5 1.5 1 0 0 1 1 1 0 Protein kinase G rubredoxin domain Zot PF05707.12 EAQ90028.1 - 0.12 11.9 0.0 0.57 9.8 0.0 1.9 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) RAP1 PF07218.11 EAQ90028.1 - 0.19 10.0 5.4 0.26 9.5 5.4 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Response_reg PF00072.24 EAQ90029.1 - 2.9e-20 72.5 0.0 3.2e-14 53.0 0.0 2.4 2 0 0 2 2 2 2 Response regulator receiver domain Bot1p PF12298.8 EAQ90030.1 - 5.8e-57 192.6 3.1 5.8e-57 192.6 3.1 1.5 2 0 0 2 2 2 1 Eukaryotic mitochondrial regulator protein Y_phosphatase3 PF13350.6 EAQ90031.1 - 7.4e-52 176.6 0.0 8.6e-52 176.4 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family COX1 PF00115.20 EAQ90033.1 - 0.0018 17.2 5.3 0.0022 16.9 5.3 1.1 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I TMEM192 PF14802.6 EAQ90033.1 - 0.037 13.1 1.4 0.042 12.9 0.5 1.5 1 1 0 1 1 1 0 TMEM192 family MARVEL PF01284.23 EAQ90033.1 - 0.08 13.0 12.3 0.15 12.1 11.9 1.7 1 1 1 2 2 2 0 Membrane-associating domain VIT1 PF01988.19 EAQ90033.1 - 0.24 11.2 3.1 0.21 11.4 2.2 1.4 1 1 0 1 1 1 0 VIT family TMEM213 PF15192.6 EAQ90033.1 - 0.58 10.2 2.7 0.32 11.0 0.3 1.8 1 1 1 2 2 2 0 TMEM213 family BAR PF03114.18 EAQ90036.1 - 8.8e-16 58.3 0.2 1.3e-15 57.7 0.2 1.1 1 0 0 1 1 1 1 BAR domain SH3_9 PF14604.6 EAQ90036.1 - 2.1e-12 46.7 0.1 3.9e-12 45.8 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EAQ90036.1 - 3.8e-12 45.6 0.3 9.2e-12 44.4 0.1 1.8 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 EAQ90036.1 - 1.3e-09 37.6 0.0 2.6e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Pex14_N PF04695.13 EAQ90036.1 - 0.0026 18.5 2.0 0.0026 18.5 2.0 1.8 2 0 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2439 PF10382.9 EAQ90037.1 - 1.6e-06 28.4 0.0 3.1e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) IATP PF04568.12 EAQ90038.1 - 0.18 12.2 0.5 0.63 10.5 0.5 1.9 1 0 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP Zn_clus PF00172.18 EAQ90040.1 - 0.23 11.6 8.8 0.42 10.8 8.8 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain dCMP_cyt_deam_1 PF00383.23 EAQ90041.1 - 4.1e-23 81.2 0.0 1.6e-22 79.3 0.0 2.0 2 1 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EAQ90041.1 - 4.2e-18 65.4 0.0 3.3e-08 33.4 0.0 2.4 2 0 0 2 2 2 2 MafB19-like deaminase Bd3614-deam PF14439.6 EAQ90041.1 - 0.018 15.1 1.6 0.12 12.5 0.3 2.4 1 1 0 2 2 2 0 Bd3614-like deaminase SNAD4 PF18750.1 EAQ90041.1 - 0.029 14.5 0.1 0.23 11.6 0.2 2.1 2 0 0 2 2 2 0 Secreted Novel AID/APOBEC-like Deaminase 4 NAD1 PF18778.1 EAQ90041.1 - 0.18 11.9 0.0 0.68 10.0 0.1 1.8 2 0 0 2 2 2 0 Novel AID APOBEC clade 1 GFA PF04828.14 EAQ90042.1 - 0.0023 18.2 0.9 0.074 13.4 0.5 4.0 4 1 1 5 5 5 3 Glutathione-dependent formaldehyde-activating enzyme Xan_ur_permease PF00860.20 EAQ90043.1 - 3.7e-25 88.4 26.6 6.8e-23 81.0 25.0 3.0 2 1 0 2 2 2 2 Permease family ANAPC4_WD40 PF12894.7 EAQ90044.1 - 1.1e-05 25.6 0.0 0.039 14.2 0.0 3.5 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EAQ90044.1 - 0.00058 20.6 0.8 5.9 7.9 0.0 4.8 5 0 0 5 5 5 1 WD domain, G-beta repeat Cytochrom_D1 PF02239.16 EAQ90044.1 - 0.015 13.8 0.0 0.028 13.0 0.0 1.3 1 0 0 1 1 1 0 Cytochrome D1 heme domain eIF2A PF08662.11 EAQ90044.1 - 0.019 14.9 0.0 0.28 11.0 0.0 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 EAQ90044.1 - 0.037 14.0 0.0 0.16 12.0 0.0 2.1 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat DRTGG PF07085.12 EAQ90044.1 - 0.18 11.6 0.0 0.36 10.6 0.0 1.5 1 0 0 1 1 1 0 DRTGG domain GRIP PF01465.20 EAQ90045.1 - 2.3e-12 46.6 0.3 5e-12 45.5 0.3 1.6 1 0 0 1 1 1 1 GRIP domain DHR10 PF18595.1 EAQ90045.1 - 0.001 19.1 17.3 0.001 19.1 17.3 10.3 5 3 6 11 11 11 2 Designed helical repeat protein 10 domain HOOK PF05622.12 EAQ90045.1 - 0.0018 16.5 19.0 0.0018 16.5 19.0 5.1 1 1 2 3 3 3 1 HOOK protein GAS PF13851.6 EAQ90045.1 - 0.0029 17.0 128.9 0.019 14.3 23.0 7.7 3 2 4 7 7 7 6 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.9 EAQ90045.1 - 0.0078 16.2 10.4 0.0078 16.2 10.4 7.7 3 1 4 7 7 7 4 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DivIC PF04977.15 EAQ90045.1 - 0.0084 15.9 1.7 0.0084 15.9 1.7 12.7 6 3 5 12 12 12 4 Septum formation initiator APG6_N PF17675.1 EAQ90045.1 - 0.3 11.6 152.5 0.34 11.4 18.1 9.5 1 1 8 9 9 8 0 Apg6 coiled-coil region Lebercilin PF15619.6 EAQ90045.1 - 0.52 9.9 130.8 0.48 10.0 17.4 5.8 4 1 2 6 6 6 0 Ciliary protein causing Leber congenital amaurosis disease Cep57_CLD PF14073.6 EAQ90045.1 - 0.61 10.1 0.0 0.61 10.1 0.0 6.4 3 2 3 6 6 4 0 Centrosome localisation domain of Cep57 Fez1 PF06818.15 EAQ90045.1 - 2 8.8 123.7 8.7 6.7 11.0 7.0 1 1 5 6 6 6 0 Fez1 TPR_MLP1_2 PF07926.12 EAQ90045.1 - 4.3 7.4 134.2 1.4 8.9 22.0 7.8 3 1 4 7 7 7 0 TPR/MLP1/MLP2-like protein TMF_TATA_bd PF12325.8 EAQ90045.1 - 4.7 7.5 119.7 0.33 11.2 9.6 9.1 3 2 6 9 9 9 0 TATA element modulatory factor 1 TATA binding DUF2477 PF10631.9 EAQ90045.1 - 5.2 7.7 4.8 34 5.1 4.8 2.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2477) zinc_ribbon_10 PF10058.9 EAQ90046.1 - 8.6e-18 63.8 0.1 1.9e-17 62.7 0.1 1.6 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein DUF2207 PF09972.9 EAQ90046.1 - 0.039 12.7 0.1 0.058 12.1 0.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) zf-RanBP PF00641.18 EAQ90046.1 - 0.22 10.9 2.8 0.37 10.1 0.3 2.1 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others GRDP-like PF07173.12 EAQ90050.1 - 3.2e-18 66.7 2.6 1.1e-12 48.8 0.6 3.1 3 0 0 3 3 3 2 Glycine-rich domain-containing protein-like Acetyltransf_10 PF13673.7 EAQ90051.1 - 3.2e-10 40.0 0.0 4.5e-10 39.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EAQ90051.1 - 6.5e-10 39.3 0.0 9.7e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EAQ90051.1 - 2.3e-08 34.3 0.0 2.9e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 EAQ90051.1 - 2.6e-05 24.1 0.0 4e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 EAQ90051.1 - 0.061 13.4 0.1 0.11 12.6 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Bac_rhamnosid_C PF17390.2 EAQ90053.1 - 1.3e-12 47.3 0.2 3.7e-12 45.9 0.2 1.8 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain Bac_rhamnosid6H PF17389.2 EAQ90053.1 - 3.1e-08 33.3 0.0 6.9e-08 32.1 0.0 1.6 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain DUF2939 PF11159.8 EAQ90053.1 - 0.072 13.5 0.3 0.32 11.4 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2939) CHASE8 PF17152.4 EAQ90053.1 - 0.18 12.0 0.4 0.46 10.7 0.4 1.6 1 0 0 1 1 1 0 Periplasmic sensor domain Zn_clus PF00172.18 EAQ90054.1 - 2.2e-08 34.1 15.5 9.8e-08 32.0 16.2 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RTA1 PF04479.13 EAQ90055.1 - 7.9e-69 231.4 18.2 7.9e-69 231.4 18.2 1.7 2 0 0 2 2 2 1 RTA1 like protein HemY_N PF07219.13 EAQ90055.1 - 0.015 15.5 1.1 0.015 15.5 1.1 3.6 5 0 0 5 5 5 0 HemY protein N-terminus Caveolin PF01146.17 EAQ90055.1 - 0.069 13.1 0.6 0.069 13.1 0.6 2.1 2 0 0 2 2 2 0 Caveolin Kelch_5 PF13854.6 EAQ90056.1 - 2.2e-09 37.1 3.4 3.1e-08 33.4 0.2 3.8 4 0 0 4 4 4 1 Kelch motif Kelch_4 PF13418.6 EAQ90056.1 - 3.1e-07 30.3 7.4 0.022 14.7 0.0 4.7 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_6 PF13964.6 EAQ90056.1 - 0.00031 20.9 10.3 0.23 11.8 0.2 5.1 3 2 1 4 4 4 1 Kelch motif Podoplanin PF05808.11 EAQ90056.1 - 0.0024 18.0 1.2 0.0044 17.1 1.2 1.4 1 0 0 1 1 1 1 Podoplanin Syndecan PF01034.20 EAQ90056.1 - 0.032 14.1 0.2 0.066 13.1 0.2 1.4 1 0 0 1 1 1 0 Syndecan domain VSP PF03302.13 EAQ90056.1 - 0.06 12.2 0.7 0.088 11.6 0.7 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein DUF2207 PF09972.9 EAQ90056.1 - 0.11 11.3 0.0 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4690 PF15756.5 EAQ90056.1 - 0.12 12.9 0.3 0.37 11.4 0.3 1.8 1 0 0 1 1 1 0 Small Novel Rich in Cartilage Glycophorin_A PF01102.18 EAQ90056.1 - 0.16 12.2 0.0 0.36 11.1 0.0 1.5 1 0 0 1 1 1 0 Glycophorin A Kelch_3 PF13415.6 EAQ90056.1 - 0.51 10.7 0.0 0.51 10.7 0.0 4.3 4 1 0 4 4 4 0 Galactose oxidase, central domain CDH-cyt PF16010.5 EAQ90057.1 - 3.4e-55 186.6 1.3 4e-55 186.3 1.3 1.1 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase HLH PF00010.26 EAQ90058.1 - 1.3e-15 57.1 0.4 2.6e-15 56.1 0.4 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain bZIP_1 PF00170.21 EAQ90058.1 - 0.014 15.5 0.4 0.014 15.5 0.4 2.0 2 0 0 2 2 2 0 bZIP transcription factor ZapB PF06005.12 EAQ90058.1 - 0.018 15.5 3.6 0.051 14.0 1.0 2.1 2 0 0 2 2 2 0 Cell division protein ZapB TolA_bind_tri PF16331.5 EAQ90058.1 - 0.032 14.3 3.1 0.041 14.0 0.2 2.1 2 0 0 2 2 2 0 TolA binding protein trimerisation bZIP_2 PF07716.15 EAQ90058.1 - 0.085 13.0 0.4 0.085 13.0 0.4 2.1 2 0 0 2 2 2 0 Basic region leucine zipper CDH-cyt PF16010.5 EAQ90061.1 - 1.1e-28 100.1 0.8 9.1e-22 77.6 0.1 2.4 1 1 1 2 2 2 2 Cytochrome domain of cellobiose dehydrogenase DOMON PF03351.17 EAQ90061.1 - 0.099 12.9 0.8 0.15 12.3 0.1 1.7 2 0 0 2 2 2 0 DOMON domain Romo1 PF10247.9 EAQ90063.1 - 0.093 13.1 1.2 0.21 12.0 1.2 1.6 1 0 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 BCS1_N PF08740.11 EAQ90064.1 - 2.6e-33 115.6 1.1 2.6e-33 115.6 1.1 1.7 2 0 0 2 2 2 1 BCS1 N terminal AAA PF00004.29 EAQ90064.1 - 3e-06 27.7 0.2 4.6e-05 23.8 0.0 2.2 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EAQ90064.1 - 0.0017 18.8 0.0 0.0028 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 EAQ90064.1 - 0.011 15.3 0.0 0.023 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EAQ90064.1 - 0.025 15.1 0.0 0.091 13.3 0.0 2.0 3 0 0 3 3 2 0 AAA domain ATPase PF06745.13 EAQ90064.1 - 0.039 13.3 0.0 0.066 12.5 0.0 1.3 1 0 0 1 1 1 0 KaiC PPV_E1_C PF00519.17 EAQ90064.1 - 0.05 12.4 0.0 0.081 11.7 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase AAA_5 PF07728.14 EAQ90064.1 - 0.051 13.6 0.1 0.096 12.7 0.1 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 EAQ90064.1 - 0.086 12.6 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EAQ90064.1 - 0.1 13.0 0.1 0.29 11.5 0.1 1.7 1 0 0 1 1 1 0 RNA helicase EAR PF07897.11 EAQ90064.1 - 0.11 12.1 0.2 0.11 12.1 0.2 1.9 2 0 0 2 2 2 0 Ethylene-responsive binding factor-associated repression AAA_22 PF13401.6 EAQ90064.1 - 0.12 12.7 0.1 0.39 11.0 0.1 1.8 2 0 0 2 2 2 0 AAA domain TIP49 PF06068.13 EAQ90064.1 - 0.28 10.3 0.0 0.64 9.2 0.0 1.5 2 0 0 2 2 2 0 TIP49 P-loop domain Herpes_UL6 PF01763.16 EAQ90065.1 - 0.029 12.9 1.1 0.04 12.4 1.1 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like DUF16 PF01519.16 EAQ90065.1 - 0.053 14.0 2.7 0.2 12.2 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function DUF16 GAS PF13851.6 EAQ90065.1 - 0.089 12.1 0.9 0.12 11.7 0.9 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding SlyX PF04102.12 EAQ90065.1 - 0.13 12.9 10.0 3.2 8.5 4.3 2.5 1 1 1 2 2 2 0 SlyX Spc7 PF08317.11 EAQ90065.1 - 0.17 10.8 3.7 0.24 10.2 3.7 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Csm1_N PF18504.1 EAQ90065.1 - 0.21 12.0 1.9 0.41 11.0 1.9 1.5 1 0 0 1 1 1 0 Csm1 N-terminal domain DivIC PF04977.15 EAQ90065.1 - 0.29 10.9 4.6 1.7 8.5 0.9 2.2 1 1 1 2 2 2 0 Septum formation initiator ATG16 PF08614.11 EAQ90065.1 - 1.4 9.1 7.8 0.16 12.2 3.5 1.5 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) XYPPX PF02162.17 EAQ90067.1 - 0.00078 19.2 76.8 0.07 12.9 28.1 4.8 2 1 2 4 4 4 3 XYPPX repeat (two copies) Pro-rich PF15240.6 EAQ90067.1 - 0.25 11.6 19.8 0.25 11.6 19.8 1.1 1 0 0 1 1 1 0 Proline-rich GST_N_3 PF13417.6 EAQ90069.1 - 3e-15 56.4 0.0 6.5e-15 55.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EAQ90069.1 - 9.2e-15 54.8 0.0 1.6e-14 54.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EAQ90069.1 - 3.7e-13 49.6 0.0 6.3e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 EAQ90069.1 - 1.2e-05 25.5 0.0 3.1e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 Glutaredoxin GST_C_3 PF14497.6 EAQ90069.1 - 0.00012 22.2 0.0 0.0002 21.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EAQ90069.1 - 0.004 17.2 0.1 0.0071 16.3 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Pex16 PF08610.10 EAQ90070.1 - 7.2e-137 455.9 0.1 8.1e-137 455.7 0.1 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) GMC_oxred_N PF00732.19 EAQ90071.1 - 1.8e-77 260.6 0.0 2.6e-77 260.1 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EAQ90071.1 - 2.1e-35 122.3 0.0 4e-35 121.5 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 EAQ90071.1 - 0.00012 21.3 0.1 0.0002 20.5 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 EAQ90071.1 - 0.0015 17.7 0.2 0.83 8.7 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 EAQ90071.1 - 0.0019 17.8 0.2 0.34 10.4 0.1 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EAQ90071.1 - 0.0022 17.3 0.0 0.0037 16.6 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EAQ90071.1 - 0.013 14.7 0.1 0.038 13.2 0.0 1.7 2 0 0 2 2 2 0 Thi4 family bZIP_2 PF07716.15 EAQ90072.1 - 8.1e-08 32.2 14.0 1.8e-07 31.2 14.0 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 EAQ90072.1 - 1.4e-05 25.1 11.5 2.9e-05 24.1 11.5 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 EAQ90072.1 - 0.019 15.5 11.0 0.044 14.3 11.0 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor NTP_transf_9 PF04248.12 EAQ90074.1 - 6.6e-11 42.0 0.0 1.3e-07 31.4 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF427) Snf7 PF03357.21 EAQ90075.1 - 1e-05 25.2 23.6 1.4e-05 24.8 23.6 1.3 1 0 0 1 1 1 1 Snf7 3-dmu-9_3-mt PF06983.13 EAQ90075.1 - 0.14 12.7 1.6 0.16 12.5 0.3 1.7 2 0 0 2 2 2 0 3-demethylubiquinone-9 3-methyltransferase Ist1 PF03398.14 EAQ90075.1 - 0.36 10.7 10.0 0.69 9.8 10.0 1.6 1 1 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway CnrY PF17524.2 EAQ90075.1 - 0.58 10.4 5.1 0.14 12.4 0.8 2.0 2 0 0 2 2 2 0 Anti-sigma factor CnrY DltD PF04914.12 EAQ90075.1 - 0.71 9.2 15.7 0.93 8.8 15.7 1.1 1 0 0 1 1 1 0 DltD protein CEL_III_C PF18054.1 EAQ90075.1 - 1.4 9.0 6.2 1.9 8.6 5.5 1.6 1 1 0 1 1 1 0 CEL-III C-terminal Vfa1 PF08432.10 EAQ90075.1 - 2.2 8.6 12.6 3.6 7.9 12.6 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DSHCT PF08148.12 EAQ90076.1 - 6.8e-52 175.4 0.6 1.6e-51 174.2 0.6 1.7 1 0 0 1 1 1 1 DSHCT (NUC185) domain Ski2_N PF17911.1 EAQ90076.1 - 5.6e-39 133.0 0.0 4.6e-38 130.1 0.0 2.3 2 0 0 2 2 2 1 Ski2 N-terminal region rRNA_proc-arch PF13234.6 EAQ90076.1 - 1.2e-27 97.5 0.0 2.1e-27 96.7 0.0 1.4 1 0 0 1 1 1 1 rRNA-processing arch domain DEAD PF00270.29 EAQ90076.1 - 2.1e-18 66.7 0.0 6e-18 65.2 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EAQ90076.1 - 1.1e-06 28.9 0.0 4.3e-06 27.0 0.0 2.1 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EAQ90076.1 - 1.9e-05 24.7 0.1 5.7e-05 23.2 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DNA_pol_phi PF04931.13 EAQ90076.1 - 0.92 7.5 5.8 1.5 6.8 5.8 1.2 1 0 0 1 1 1 0 DNA polymerase phi dUTPase PF00692.19 EAQ90077.1 - 1.8e-13 50.3 0.0 2.3e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 dUTPase adh_short_C2 PF13561.6 EAQ90078.1 - 3.1e-60 203.6 0.1 3.6e-60 203.4 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EAQ90078.1 - 3.7e-42 144.0 0.0 4.9e-42 143.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EAQ90078.1 - 8.2e-10 38.9 0.6 1.3e-09 38.2 0.6 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 EAQ90078.1 - 4.1e-05 23.5 0.1 6.9e-05 22.8 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_25 PF13649.6 EAQ90078.1 - 0.00077 20.1 0.0 0.0018 18.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EAQ90078.1 - 0.0056 17.4 0.0 0.012 16.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain UDPG_MGDP_dh_N PF03721.14 EAQ90078.1 - 0.011 15.3 0.0 0.016 14.7 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain THF_DHG_CYH_C PF02882.19 EAQ90078.1 - 0.014 14.7 0.1 0.04 13.2 0.1 1.8 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain RecC_C PF17946.1 EAQ90078.1 - 0.043 13.6 0.0 0.084 12.7 0.0 1.4 1 0 0 1 1 1 0 RecC C-terminal domain Ldh_1_N PF00056.23 EAQ90078.1 - 0.096 12.8 0.1 0.3 11.2 0.1 1.9 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain ICL PF00463.21 EAQ90079.1 - 3e-193 643.1 0.3 3.5e-193 642.9 0.3 1.0 1 0 0 1 1 1 1 Isocitrate lyase family Swi3 PF07962.12 EAQ90080.1 - 1.6e-30 104.9 0.7 2.7e-30 104.2 0.3 1.6 2 0 0 2 2 2 1 Replication Fork Protection Component Swi3 Nnf1 PF03980.14 EAQ90080.1 - 4.7 7.6 6.5 6.2 7.3 0.3 3.2 3 1 0 3 3 3 0 Nnf1 APH PF01636.23 EAQ90081.1 - 0.0026 17.7 0.1 0.0039 17.1 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 EAQ90081.1 - 0.0034 16.7 0.0 0.0046 16.3 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase NADH-u_ox-rdase PF10785.9 EAQ90082.1 - 8e-29 100.2 0.4 1.4e-28 99.4 0.4 1.4 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.7 EAQ90082.1 - 2.9e-25 88.0 0.0 5e-25 87.3 0.0 1.3 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit Glyco_hydro_61 PF03443.14 EAQ90083.1 - 7e-50 169.8 0.1 8e-49 166.4 0.1 2.0 1 1 1 2 2 2 1 Glycosyl hydrolase family 61 CBM_1 PF00734.18 EAQ90083.1 - 2.6e-09 36.9 12.4 2.6e-09 36.9 12.4 3.0 2 2 0 2 2 2 1 Fungal cellulose binding domain SGL PF08450.12 EAQ90084.1 - 1.4e-19 70.7 0.0 2.6e-19 69.8 0.0 1.4 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 EAQ90084.1 - 3.4e-05 23.9 0.0 0.0006 19.9 0.0 2.6 2 1 0 2 2 2 1 Strictosidine synthase Arylesterase PF01731.20 EAQ90084.1 - 0.069 13.4 0.0 0.53 10.5 0.0 2.3 2 0 0 2 2 2 0 Arylesterase SWIRM PF04433.17 EAQ90087.1 - 3.1e-14 53.1 0.1 4.4e-13 49.4 0.0 2.2 2 0 0 2 2 2 1 SWIRM domain adh_short PF00106.25 EAQ90088.1 - 6.7e-42 143.2 0.6 8.9e-42 142.8 0.6 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EAQ90088.1 - 1.6e-39 135.8 0.4 3.1e-39 134.9 0.4 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EAQ90088.1 - 8.1e-10 38.9 1.5 2.4e-09 37.4 0.1 2.0 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 EAQ90088.1 - 0.00035 20.1 0.2 0.00055 19.5 0.2 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 EAQ90088.1 - 0.00088 19.4 0.1 0.0017 18.4 0.1 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 EAQ90088.1 - 0.0012 18.7 0.3 0.011 15.6 0.2 2.0 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 EAQ90088.1 - 0.0014 17.8 0.3 0.003 16.7 0.3 1.5 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Glyco_tran_WecB PF03808.13 EAQ90088.1 - 0.0021 18.1 0.2 0.048 13.6 0.0 2.5 2 1 1 3 3 3 1 Glycosyl transferase WecB/TagA/CpsF family ADH_zinc_N PF00107.26 EAQ90088.1 - 0.0036 17.3 0.1 0.0068 16.4 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase GDP_Man_Dehyd PF16363.5 EAQ90088.1 - 0.0094 15.4 1.2 0.0097 15.3 0.1 1.5 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Sacchrp_dh_NADP PF03435.18 EAQ90088.1 - 0.011 16.0 0.1 0.022 15.0 0.1 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 EAQ90088.1 - 0.019 14.8 0.5 0.03 14.2 0.0 1.6 2 0 0 2 2 2 0 NAD(P)H-binding NAD_binding_7 PF13241.6 EAQ90088.1 - 0.03 14.7 0.4 0.091 13.2 0.4 1.9 2 1 0 2 2 2 0 Putative NAD(P)-binding ApbA PF02558.16 EAQ90088.1 - 0.042 13.5 0.1 0.072 12.7 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DUF1776 PF08643.10 EAQ90088.1 - 0.08 12.3 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Gpr1_Fun34_YaaH PF01184.19 EAQ90089.1 - 1.2e-13 51.2 9.6 8.7e-09 35.3 5.3 2.4 1 1 1 2 2 2 2 GPR1/FUN34/yaaH family DUF1691 PF07950.11 EAQ90090.1 - 0.00011 22.9 0.0 0.00017 22.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1691) zf-C2H2_jaz PF12171.8 EAQ90091.1 - 1.1e-07 31.9 3.7 1.7e-07 31.3 3.7 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EAQ90091.1 - 0.00014 22.1 0.9 0.00023 21.4 0.9 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 EAQ90091.1 - 0.022 15.1 0.2 0.031 14.6 0.2 1.2 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 EAQ90091.1 - 0.083 13.4 0.8 0.14 12.7 0.8 1.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EAQ90091.1 - 0.12 13.3 0.3 0.22 12.4 0.3 1.4 1 0 0 1 1 1 0 C2H2-type zinc finger zf-DBF PF07535.12 EAQ90091.1 - 0.32 11.1 2.4 0.54 10.4 2.4 1.3 1 0 0 1 1 1 0 DBF zinc finger K_channel_TID PF07941.11 EAQ90091.1 - 2.5 8.6 9.5 1.2 9.7 7.0 1.7 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain Zn_clus PF00172.18 EAQ90092.1 - 0.00086 19.4 4.1 0.0027 17.8 4.1 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EAQ90092.1 - 0.0014 17.8 0.0 0.0075 15.3 0.0 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Cu_amine_oxid PF01179.20 EAQ90093.1 - 6.8e-159 529.2 0.0 8.8e-159 528.8 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 EAQ90093.1 - 1.3e-06 28.7 0.0 3e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 EAQ90093.1 - 8.9e-05 22.7 0.0 0.00017 21.7 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Epimerase PF01370.21 EAQ90094.1 - 6.7e-16 58.5 0.0 9.1e-16 58.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EAQ90094.1 - 3.7e-10 39.7 0.0 5.4e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EAQ90094.1 - 3.4e-08 32.9 0.0 4.6e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EAQ90094.1 - 3.7e-07 29.6 0.0 1.2e-06 27.9 0.0 1.7 2 0 0 2 2 2 1 Male sterility protein NmrA PF05368.13 EAQ90094.1 - 0.055 13.0 0.1 0.19 11.3 0.1 1.8 2 0 0 2 2 2 0 NmrA-like family adh_short PF00106.25 EAQ90094.1 - 0.062 12.8 0.6 0.6 9.5 0.1 2.3 2 1 0 2 2 2 0 short chain dehydrogenase Lipase_GDSL_2 PF13472.6 EAQ90095.1 - 2.1e-11 44.5 0.0 2.8e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EAQ90095.1 - 0.0006 19.8 0.0 0.0013 18.7 0.0 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase ALGX PF16822.5 EAQ90095.1 - 0.0022 17.7 0.0 0.49 10.0 0.0 2.1 2 0 0 2 2 2 2 SGNH hydrolase-like domain, acetyltransferase AlgX TRAM_LAG1_CLN8 PF03798.16 EAQ90096.1 - 8.2e-48 162.8 14.0 1.2e-47 162.2 14.0 1.2 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.11 EAQ90096.1 - 2e-18 65.8 0.0 4.7e-18 64.6 0.0 1.7 1 0 0 1 1 1 1 TRAM1-like protein RRM_1 PF00076.22 EAQ90097.1 - 4.4e-15 55.3 0.0 6.5e-14 51.5 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EAQ90097.1 - 0.0039 17.3 0.0 0.013 15.6 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif DUF5035 PF16438.5 EAQ90097.1 - 0.095 12.6 1.3 0.24 11.2 1.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5035) DUF4614 PF15391.6 EAQ90097.1 - 1.3 9.0 4.9 2 8.4 4.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) WD40 PF00400.32 EAQ90098.1 - 9.1e-08 32.7 0.1 0.032 15.1 0.0 3.2 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAQ90098.1 - 5.3e-05 23.4 0.0 0.0035 17.6 0.0 3.4 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nbas_N PF15492.6 EAQ90098.1 - 6.6e-05 22.4 0.1 0.0024 17.2 0.0 2.4 2 1 0 2 2 2 1 Neuroblastoma-amplified sequence, N terminal Ge1_WD40 PF16529.5 EAQ90098.1 - 0.019 14.0 0.1 0.29 10.1 0.0 2.0 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein IKI3 PF04762.12 EAQ90098.1 - 0.1 10.6 0.0 0.57 8.1 0.0 2.1 2 1 0 3 3 3 0 IKI3 family WD40_3 PF15911.5 EAQ90098.1 - 0.13 12.3 0.0 1 9.4 0.0 2.3 2 1 0 2 2 2 0 WD domain, G-beta repeat Septin PF00735.18 EAQ90099.1 - 3.2e-107 358.0 0.0 6.8e-107 356.9 0.0 1.4 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 EAQ90099.1 - 4e-05 23.7 0.0 9.5e-05 22.4 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 EAQ90099.1 - 0.0019 18.3 3.1 1.7 8.7 0.0 3.1 2 1 1 3 3 3 2 Dynamin family RsgA_GTPase PF03193.16 EAQ90099.1 - 0.031 14.2 0.4 0.031 14.2 0.4 2.3 2 1 0 2 2 2 0 RsgA GTPase IIGP PF05049.13 EAQ90099.1 - 0.046 12.8 0.0 0.088 11.8 0.0 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) GTP_EFTU PF00009.27 EAQ90099.1 - 0.083 12.4 0.0 0.44 10.0 0.0 2.1 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Roc PF08477.13 EAQ90099.1 - 0.15 12.3 0.0 0.31 11.2 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase EB1 PF03271.17 EAQ90099.1 - 0.17 12.2 0.9 5.6 7.3 1.1 2.6 2 0 0 2 2 2 0 EB1-like C-terminal motif AAA_22 PF13401.6 EAQ90099.1 - 0.24 11.7 1.7 0.38 11.0 0.2 2.1 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.6 EAQ90099.1 - 4.9 7.6 7.5 18 5.7 3.4 2.2 2 1 0 2 2 2 0 AAA domain Bax1-I PF01027.20 EAQ90100.1 - 6.3e-55 186.2 27.0 7.3e-55 186.0 27.0 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF308 PF03729.13 EAQ90100.1 - 1.1 9.7 16.1 2.2 8.6 3.6 3.2 1 1 3 4 4 4 0 Short repeat of unknown function (DUF308) DUF5381 PF17353.2 EAQ90100.1 - 1.4 8.6 6.5 3.4 7.4 6.5 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5381) TMEM171 PF15471.6 EAQ90100.1 - 2.5 7.0 5.7 2.8 6.8 0.2 2.2 2 0 0 2 2 2 0 Transmembrane protein family 171 DUF4407 PF14362.6 EAQ90100.1 - 6.5 6.0 12.2 0.22 10.8 4.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DLIC PF05783.11 EAQ90101.1 - 4.2e-31 108.3 0.5 1e-29 103.7 0.0 2.7 2 1 0 2 2 2 1 Dynein light intermediate chain (DLIC) DUF4012 PF13196.6 EAQ90101.1 - 0.15 12.5 0.2 0.47 10.9 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4012) Thioredox_DsbH PF03190.15 EAQ90102.1 - 1.1e-62 210.8 0.0 2.2e-62 209.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.6 EAQ90102.1 - 0.034 14.3 0.0 0.18 12.0 0.0 2.3 3 0 0 3 3 3 0 Thioredoxin-like Glyco_hydro_9 PF00759.19 EAQ90102.1 - 3.7 6.9 8.0 0.044 13.2 0.3 1.7 2 0 0 2 2 2 0 Glycosyl hydrolase family 9 DUF4360 PF14273.6 EAQ90104.1 - 1.5e-66 223.7 4.0 1.7e-66 223.5 4.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) hGDE_N PF14699.6 EAQ90104.1 - 0.067 13.3 0.2 0.16 12.1 0.2 1.7 1 1 0 1 1 1 0 N-terminal domain from the human glycogen debranching enzyme Citrate_synt PF00285.21 EAQ90105.1 - 1.8e-84 283.9 0.0 1.6e-78 264.3 0.0 2.1 1 1 1 2 2 2 2 Citrate synthase, C-terminal domain Gln-synt_C PF00120.24 EAQ90106.1 - 5.3e-86 288.7 0.0 6.7e-86 288.4 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain AMP-binding PF00501.28 EAQ90108.1 - 1.6e-66 224.7 0.0 9e-65 218.9 0.0 2.0 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EAQ90108.1 - 1.7e-14 54.6 0.3 5.1e-14 53.0 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Abhydrolase_6 PF12697.7 EAQ90110.1 - 1.1e-11 45.8 9.4 1.5e-11 45.3 9.4 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EAQ90110.1 - 5e-08 32.9 2.0 9.3e-08 32.0 2.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EAQ90110.1 - 1.2e-06 28.0 0.3 2.7e-06 26.8 0.3 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF4215 PF13948.6 EAQ90111.1 - 9.1e-24 83.6 176.8 0.016 15.6 7.3 15.1 1 1 13 14 14 14 14 Domain of unknown function (DUF4215) WD40 PF00400.32 EAQ90112.1 - 1.6e-10 41.4 0.5 0.04 14.8 0.0 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAQ90112.1 - 0.095 13.0 0.0 8.5 6.8 0.0 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain GDC-P PF02347.16 EAQ90113.1 - 1.5e-159 531.5 0.0 2.7e-156 520.7 0.0 2.2 2 0 0 2 2 2 2 Glycine cleavage system P-protein Aminotran_5 PF00266.19 EAQ90113.1 - 0.027 13.4 0.0 0.39 9.6 0.0 2.3 2 0 0 2 2 2 0 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 EAQ90113.1 - 0.032 12.7 0.0 0.052 12.1 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Tom5 PF10642.9 EAQ90114.1 - 1.3e-13 50.8 2.6 1.5e-13 50.5 2.6 1.1 1 0 0 1 1 1 1 Mitochondrial import receptor subunit or translocase Nup54 PF13874.6 EAQ90115.1 - 7.5e-40 136.3 0.1 7.5e-40 136.3 0.1 3.0 3 0 0 3 3 2 1 Nucleoporin complex subunit 54 Nup54_57_C PF18570.1 EAQ90115.1 - 2.8e-15 55.6 8.5 5.2e-15 54.7 8.5 1.5 1 0 0 1 1 1 1 NUP57/Nup54 C-terminal domain DUF2722 PF10846.8 EAQ90115.1 - 3.6e-08 32.8 5.6 4.1e-08 32.6 5.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Peptidase_C58 PF03543.14 EAQ90115.1 - 0.00087 19.0 4.8 0.0085 15.8 2.4 2.4 2 0 0 2 2 2 1 Yersinia/Haemophilus virulence surface antigen Adhesin_P1_N PF18652.1 EAQ90115.1 - 0.0041 17.1 1.9 0.0041 17.1 1.9 2.8 3 0 0 3 3 2 1 Adhesin P1 N-terminal domain Spt20 PF12090.8 EAQ90115.1 - 0.01 15.5 25.5 0.01 15.5 25.5 1.6 2 0 0 2 2 2 0 Spt20 family TFIIA PF03153.13 EAQ90115.1 - 0.031 14.3 23.1 0.058 13.4 23.1 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Iso_dh PF00180.20 EAQ90115.1 - 0.11 11.6 0.1 0.17 11.0 0.1 1.2 1 0 0 1 1 1 0 Isocitrate/isopropylmalate dehydrogenase LEA_3 PF03242.13 EAQ90115.1 - 0.12 13.1 1.1 3.8 8.3 0.8 2.9 2 1 1 3 3 3 0 Late embryogenesis abundant protein PMSI1 PF15322.6 EAQ90115.1 - 0.12 11.8 4.2 0.21 11.0 4.2 1.3 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative Suf PF05843.14 EAQ90115.1 - 0.27 11.2 12.3 0.61 10.0 12.3 1.6 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) eIF-3_zeta PF05091.12 EAQ90115.1 - 0.41 9.6 9.3 0.67 8.9 9.3 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Ndc1_Nup PF09531.10 EAQ90115.1 - 0.41 9.3 4.2 0.57 8.8 4.2 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Presenilin PF01080.17 EAQ90115.1 - 0.99 8.1 6.2 1.4 7.6 6.2 1.2 1 0 0 1 1 1 0 Presenilin DUF4834 PF16118.5 EAQ90115.1 - 1.6 9.7 12.7 0.58 11.2 9.7 1.7 2 0 0 2 2 1 0 Domain of unknown function (DUF4834) DUF3464 PF11947.8 EAQ90115.1 - 2.9 7.6 6.5 6.2 6.5 6.5 1.6 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 UPF0560 PF10577.9 EAQ90115.1 - 8.9 4.7 15.7 14 4.0 15.7 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 CHCH PF06747.13 EAQ90116.1 - 1.7e-08 34.4 17.7 1.3e-07 31.6 7.0 2.7 3 0 0 3 3 3 2 CHCH domain CX9C PF16860.5 EAQ90116.1 - 2.7e-07 30.5 9.0 1.6e-05 24.8 4.4 2.3 2 0 0 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Cmc1 PF08583.10 EAQ90116.1 - 0.0018 18.3 11.4 0.035 14.1 0.9 2.2 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.9 EAQ90116.1 - 0.018 15.3 8.5 2.1 8.7 4.6 2.7 2 1 0 2 2 2 0 Cytochrome c oxidase assembly protein PET191 Kre28 PF17097.5 EAQ90116.1 - 0.071 12.0 0.2 0.087 11.8 0.2 1.0 1 0 0 1 1 1 0 Spindle pole body component NDUF_B7 PF05676.13 EAQ90116.1 - 1.1 9.1 7.4 12 5.7 0.0 2.6 2 1 0 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) CAP PF00188.26 EAQ90118.1 - 4.8e-16 59.7 2.0 7.2e-16 59.2 2.0 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family COesterase PF00135.28 EAQ90119.1 - 4.7e-56 190.7 0.0 6.3e-56 190.3 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EAQ90119.1 - 1.6e-08 34.7 0.7 5.1e-08 33.0 0.7 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EAQ90119.1 - 0.0008 18.4 0.0 0.053 12.4 0.0 2.1 2 0 0 2 2 2 2 Steryl acetyl hydrolase Hydrolase_4 PF12146.8 EAQ90119.1 - 0.04 13.2 0.1 0.078 12.2 0.1 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 UvrD_C_2 PF13538.6 EAQ90120.1 - 0.01 15.6 0.0 0.035 13.9 0.0 2.0 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain PIF1 PF05970.14 EAQ90120.1 - 0.21 10.7 0.1 0.38 9.9 0.1 1.3 1 0 0 1 1 1 0 PIF1-like helicase Glyco_hydro_16 PF00722.21 EAQ90121.1 - 5.8e-16 58.5 0.0 1.6e-15 57.1 0.0 1.8 1 1 1 2 2 2 1 Glycosyl hydrolases family 16 Glyco_trans_2_3 PF13632.6 EAQ90122.1 - 4.2e-49 167.1 10.1 4.2e-49 167.1 10.1 2.4 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 EAQ90122.1 - 3.3e-05 23.8 0.0 9.2e-05 22.3 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 EAQ90122.1 - 0.062 12.8 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 21 HET PF06985.11 EAQ90123.1 - 1.7e-41 142.0 0.4 3e-41 141.2 0.4 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.7 EAQ90123.1 - 4.6e-18 65.6 0.7 5.3e-09 36.5 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAQ90123.1 - 8.5e-14 51.7 0.2 9.2e-05 22.9 0.0 4.3 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAQ90123.1 - 7.4e-13 47.4 0.9 0.027 15.0 0.0 4.9 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 EAQ90123.1 - 1.7e-09 37.7 8.8 0.047 14.1 0.1 5.0 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 EAQ90123.1 - 4.3e-06 26.9 1.7 0.18 12.2 0.1 4.4 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Mur_ligase PF01225.25 EAQ90123.1 - 0.00066 20.0 1.4 4.9 7.6 1.4 3.8 1 1 0 1 1 1 1 Mur ligase family, catalytic domain ABC_tran PF00005.27 EAQ90124.1 - 7.5e-49 165.8 0.0 3e-26 92.6 0.0 4.0 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EAQ90124.1 - 1.6e-15 57.7 6.7 0.0001 22.2 0.0 4.9 2 2 1 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EAQ90124.1 - 8.9e-13 48.2 0.6 0.002 17.6 0.0 4.5 3 2 0 3 3 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EAQ90124.1 - 6.1e-10 39.9 0.4 8.3e-05 23.2 0.0 3.0 3 0 0 3 3 3 2 AAA domain Chromo PF00385.24 EAQ90124.1 - 6.4e-08 32.4 0.0 1.3e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain MMR_HSR1 PF01926.23 EAQ90124.1 - 4.4e-07 30.0 0.0 0.0039 17.3 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 EAQ90124.1 - 6.3e-07 29.0 0.8 0.0094 15.7 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EAQ90124.1 - 2.6e-06 27.4 0.1 0.025 14.5 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 EAQ90124.1 - 7.5e-05 23.0 0.2 0.84 9.9 0.0 3.1 2 1 0 2 2 2 2 AAA domain AAA_18 PF13238.6 EAQ90124.1 - 0.00013 22.5 0.1 0.19 12.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 EAQ90124.1 - 0.00027 20.7 0.2 0.22 11.2 0.2 2.5 2 0 0 2 2 2 2 AAA ATPase domain DUF87 PF01935.17 EAQ90124.1 - 0.00035 20.7 0.7 0.38 10.8 0.0 3.6 3 0 0 3 3 3 1 Helicase HerA, central domain AAA_28 PF13521.6 EAQ90124.1 - 0.00042 20.6 0.0 0.026 14.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EAQ90124.1 - 0.0013 18.9 0.0 3 8.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 EAQ90124.1 - 0.0018 18.7 0.1 3.8 7.9 0.0 2.6 2 0 0 2 2 2 2 RNA helicase SbcCD_C PF13558.6 EAQ90124.1 - 0.0023 18.1 0.0 1.5 9.1 0.0 3.4 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit NACHT PF05729.12 EAQ90124.1 - 0.0024 17.8 0.3 0.95 9.4 0.0 2.6 2 0 0 2 2 2 1 NACHT domain MeaB PF03308.16 EAQ90124.1 - 0.003 16.6 0.1 0.8 8.6 0.0 2.4 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_13 PF13166.6 EAQ90124.1 - 0.0089 14.7 0.0 0.95 8.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 EAQ90124.1 - 0.012 16.1 0.0 6 7.3 0.0 2.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EAQ90124.1 - 0.013 15.9 0.1 1.5 9.2 0.0 3.0 3 0 0 3 3 2 0 AAA ATPase domain AAA_24 PF13479.6 EAQ90124.1 - 0.014 15.2 1.1 0.52 10.0 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_27 PF13514.6 EAQ90124.1 - 0.021 14.4 0.0 7.8 6.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 EAQ90124.1 - 0.022 14.8 0.2 0.64 10.1 0.0 2.9 3 1 0 3 3 2 0 Dynamin family AAA_30 PF13604.6 EAQ90124.1 - 0.024 14.4 1.9 3.1 7.5 0.0 3.1 3 0 0 3 3 2 0 AAA domain PduV-EutP PF10662.9 EAQ90124.1 - 0.029 14.1 0.0 0.83 9.4 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NB-ARC PF00931.22 EAQ90124.1 - 0.034 13.3 0.0 2.6 7.2 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain HEAT_2 PF13646.6 EAQ90124.1 - 0.047 14.1 2.1 2.7 8.5 0.0 3.3 3 1 1 4 4 2 0 HEAT repeats DUF3584 PF12128.8 EAQ90124.1 - 0.051 11.1 1.2 3.4 5.0 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) AAA_14 PF13173.6 EAQ90124.1 - 0.073 13.1 0.0 11 6.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain DNA_ligase_OB_2 PF14743.6 EAQ90124.1 - 0.086 12.9 0.1 0.46 10.5 0.1 2.2 2 0 0 2 2 1 0 DNA ligase OB-like domain NTPase_1 PF03266.15 EAQ90124.1 - 0.086 12.7 0.6 13 5.7 0.1 3.1 4 0 0 4 4 2 0 NTPase TsaE PF02367.17 EAQ90124.1 - 0.096 12.7 0.3 21 5.1 0.1 2.8 3 0 0 3 3 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Roc PF08477.13 EAQ90124.1 - 0.1 12.8 0.0 15 5.9 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase DUF4888 PF16229.5 EAQ90124.1 - 0.11 12.4 0.0 0.27 11.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4888) DUF815 PF05673.13 EAQ90124.1 - 0.15 11.2 0.1 5.9 6.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Fibrinogen_aC PF12160.8 EAQ90125.1 - 0.015 15.1 0.1 0.029 14.2 0.0 1.5 1 1 1 2 2 2 0 Fibrinogen alpha C domain RRM_1 PF00076.22 EAQ90126.1 - 9.5e-15 54.2 0.0 1.4e-14 53.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EAQ90126.1 - 2.7e-05 23.8 0.0 4.4e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pectate_lyase_3 PF12708.7 EAQ90130.1 - 2.9e-80 269.1 5.7 8.7e-71 238.2 1.0 2.5 2 0 0 2 2 2 2 Pectate lyase superfamily protein Beta_helix PF13229.6 EAQ90130.1 - 4.1e-05 23.5 4.2 0.017 15.0 1.0 2.9 2 0 0 2 2 2 2 Right handed beta helix region Rpp20 PF12328.8 EAQ90132.1 - 5.7e-24 84.6 0.0 7.2e-24 84.3 0.0 1.1 1 0 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.21 EAQ90132.1 - 1.7e-08 34.2 0.0 3.1e-08 33.3 0.0 1.5 1 1 0 1 1 1 1 Alba Chorion_3 PF05387.11 EAQ90132.1 - 0.023 14.4 0.2 0.033 13.8 0.2 1.3 1 0 0 1 1 1 0 Chorion family 3 Rogdi_lz PF10259.9 EAQ90133.1 - 1.2e-102 342.9 0.4 1.4e-102 342.7 0.4 1.0 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein NIPSNAP PF07978.13 EAQ90134.1 - 1.1e-38 131.6 0.5 1.4e-29 102.4 0.1 2.3 2 0 0 2 2 2 2 NIPSNAP Chorion_2 PF03964.15 EAQ90134.1 - 0.12 13.2 4.1 0.26 12.1 4.1 1.6 1 0 0 1 1 1 0 Chorion family 2 SR-25 PF10500.9 EAQ90134.1 - 0.19 11.3 8.6 0.3 10.7 8.6 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein ATP-synt_J PF04911.12 EAQ90135.1 - 3.1e-07 29.9 7.9 3.7e-05 23.2 1.9 2.1 1 1 1 2 2 2 2 ATP synthase j chain FSH1 PF03959.13 EAQ90136.1 - 3.4e-12 46.5 0.0 4.3e-12 46.2 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) DUF1674 PF07896.12 EAQ90137.1 - 0.059 13.9 1.2 0.19 12.2 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1674) Clr5 PF14420.6 EAQ90138.1 - 1.2e-18 67.1 3.7 1.9e-18 66.4 3.7 1.3 1 0 0 1 1 1 1 Clr5 domain Sugar_tr PF00083.24 EAQ90139.1 - 5.6e-77 259.5 24.6 6.7e-77 259.3 24.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EAQ90139.1 - 2.2e-15 56.4 31.9 2.2e-15 56.4 31.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily PalH PF08733.10 EAQ90139.1 - 0.8 8.6 6.0 1.4 7.8 6.0 1.4 1 0 0 1 1 1 0 PalH/RIM21 HNH_2 PF13391.6 EAQ90141.1 - 3e-10 40.1 0.3 3e-10 40.1 0.3 1.9 2 0 0 2 2 2 1 HNH endonuclease Methyltransf_11 PF08241.12 EAQ90142.1 - 7.2e-18 65.0 0.0 1.7e-17 63.9 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAQ90142.1 - 6e-15 55.7 0.1 1.4e-14 54.5 0.1 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EAQ90142.1 - 4.9e-13 49.2 0.0 8.7e-13 48.4 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAQ90142.1 - 2.8e-12 46.7 0.0 3.8e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EAQ90142.1 - 1.9e-08 35.0 0.1 3.7e-08 34.0 0.0 1.5 2 0 0 2 2 1 1 Methyltransferase domain CMAS PF02353.20 EAQ90142.1 - 3e-08 33.3 0.0 3.6e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 EAQ90142.1 - 1.4e-05 24.5 0.0 0.00066 19.1 0.0 2.1 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 EAQ90142.1 - 0.00013 21.6 0.0 0.0002 20.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 EAQ90142.1 - 0.00021 21.3 0.0 0.00029 20.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 EAQ90142.1 - 0.0005 19.5 0.0 0.00082 18.8 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB NodS PF05401.11 EAQ90142.1 - 0.0087 15.7 0.0 0.012 15.2 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) PCMT PF01135.19 EAQ90142.1 - 0.0091 15.8 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.7 EAQ90142.1 - 0.011 15.6 0.0 0.018 14.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain TPMT PF05724.11 EAQ90142.1 - 0.024 14.3 0.0 0.038 13.7 0.0 1.4 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) MetW PF07021.12 EAQ90142.1 - 0.053 13.1 0.0 0.085 12.4 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Met_10 PF02475.16 EAQ90142.1 - 0.064 13.0 0.0 0.069 12.9 0.0 1.2 1 1 0 1 1 1 0 Met-10+ like-protein PrmA PF06325.13 EAQ90142.1 - 0.1 12.0 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_15 PF09445.10 EAQ90142.1 - 0.12 11.9 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase UPF0020 PF01170.18 EAQ90142.1 - 0.17 11.6 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 G-alpha PF00503.20 EAQ90143.1 - 0.0015 17.8 0.3 0.0026 17.0 0.2 1.3 1 1 0 1 1 1 1 G-protein alpha subunit Pox_A32 PF04665.12 EAQ90143.1 - 0.0067 15.9 0.0 0.0093 15.5 0.0 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein MCM PF00493.23 EAQ90143.1 - 0.039 13.1 0.0 0.052 12.6 0.0 1.1 1 0 0 1 1 1 0 MCM P-loop domain Arf PF00025.21 EAQ90143.1 - 0.12 11.8 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 ADP-ribosylation factor family p450 PF00067.22 EAQ90145.1 - 4.5e-44 151.0 0.0 6.4e-44 150.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_16 PF00722.21 EAQ90146.1 - 2.3e-39 134.7 0.8 3.7e-39 134.0 0.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 FixQ PF05545.11 EAQ90146.1 - 0.3 11.1 1.0 0.66 10.0 1.0 1.5 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ Myb_DNA-binding PF00249.31 EAQ90147.1 - 0.0066 16.6 0.2 0.025 14.8 0.2 2.1 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF123 PF01986.16 EAQ90147.1 - 0.0087 16.6 0.3 0.086 13.4 0.1 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF123 Myb_DNA-bind_6 PF13921.6 EAQ90147.1 - 0.033 14.4 0.9 0.11 12.8 0.1 2.3 2 0 0 2 2 2 0 Myb-like DNA-binding domain HTH_Tnp_1 PF01527.20 EAQ90147.1 - 0.037 14.3 0.3 0.1 12.9 0.3 1.7 1 0 0 1 1 1 0 Transposase HTH_32 PF13565.6 EAQ90147.1 - 0.58 10.8 9.0 0.099 13.3 0.8 3.4 3 1 1 4 4 4 0 Homeodomain-like domain APH PF01636.23 EAQ90148.1 - 7.1e-19 68.7 0.0 3.8e-18 66.3 0.0 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family SDA1 PF05285.12 EAQ90148.1 - 3.2 7.1 34.1 5.2 6.4 34.1 1.2 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 EAQ90148.1 - 5.8 5.1 27.0 8.3 4.6 27.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 EAQ90148.1 - 7.6 4.6 31.8 13 3.9 31.8 1.2 1 0 0 1 1 1 0 Nop14-like family YjeF_N PF03853.15 EAQ90152.1 - 3e-13 50.0 0.1 4.5e-06 26.7 0.0 2.1 1 1 1 2 2 2 2 YjeF-related protein N-terminus DprA_WH PF17782.1 EAQ90152.1 - 0.15 12.2 0.1 0.41 10.8 0.1 1.7 1 0 0 1 1 1 0 DprA winged helix domain Ribosomal_S16 PF00886.19 EAQ90153.1 - 6.6e-26 90.2 0.0 9.6e-26 89.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S16 Aa_trans PF01490.18 EAQ90154.1 - 2.8e-81 273.3 6.3 3.9e-81 272.8 6.3 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Abhydrolase_9_N PF15420.6 EAQ90154.1 - 0.014 15.4 0.7 0.014 15.4 0.7 2.5 3 0 0 3 3 3 0 Alpha/beta-hydrolase family N-terminus MFS_1 PF07690.16 EAQ90155.1 - 3e-18 65.9 44.0 2.1e-17 63.1 42.2 2.4 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 EAQ90155.1 - 1.3e-06 27.1 21.0 2e-06 26.6 21.0 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Hum_adeno_E3A PF05393.11 EAQ90155.1 - 0.016 15.2 2.4 0.8 9.7 0.2 2.4 2 0 0 2 2 2 0 Human adenovirus early E3A glycoprotein Reprolysin_2 PF13574.6 EAQ90156.1 - 0.017 15.0 0.0 0.018 15.0 0.0 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 EAQ90156.1 - 0.03 14.5 0.0 0.03 14.5 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12 Dynactin_p22 PF07426.11 EAQ90157.1 - 6.4e-05 22.9 0.0 8.8e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Dynactin subunit p22 DUF4404 PF14357.6 EAQ90157.1 - 0.035 14.7 0.3 0.12 13.0 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) SH3_1 PF00018.28 EAQ90159.1 - 5.5e-09 35.5 0.0 8.5e-09 34.9 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EAQ90159.1 - 2.8e-06 27.1 0.0 6e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EAQ90159.1 - 4.5e-06 26.2 0.0 7.6e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain Bax1-I PF01027.20 EAQ90159.1 - 0.13 12.1 11.7 0.18 11.6 11.7 1.1 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 DUF2070 PF09843.9 EAQ90159.1 - 8.9 4.5 9.4 12 4.1 9.4 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DASH_Spc19 PF08287.11 EAQ90160.1 - 1.5e-46 158.1 0.0 2.4e-46 157.5 0.0 1.3 1 0 0 1 1 1 1 Spc19 ABC2_membrane PF01061.24 EAQ90162.1 - 1.9e-85 285.5 56.9 6.4e-44 149.9 16.6 2.5 3 0 0 3 3 3 2 ABC-2 type transporter PDR_CDR PF06422.12 EAQ90162.1 - 1.7e-32 111.2 0.2 8.3e-25 86.5 0.0 3.2 2 0 0 2 2 2 2 CDR ABC transporter ABC_tran PF00005.27 EAQ90162.1 - 5.7e-28 98.1 0.1 1.9e-15 57.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EAQ90162.1 - 4.1e-05 23.5 0.0 0.098 12.4 0.0 2.3 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 EAQ90162.1 - 9.1e-05 23.0 0.0 0.00018 22.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EAQ90162.1 - 0.00061 19.7 0.1 0.0012 18.8 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase ABC2_membrane_3 PF12698.7 EAQ90162.1 - 0.00068 18.9 16.1 0.00068 18.9 16.1 2.7 2 1 0 2 2 2 1 ABC-2 family transporter protein AAA_33 PF13671.6 EAQ90162.1 - 0.0012 19.0 0.0 0.011 15.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EAQ90162.1 - 0.0015 19.0 0.1 0.0042 17.5 0.1 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.6 EAQ90162.1 - 0.0024 18.1 0.0 0.0062 16.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain ABC_trans_N PF14510.6 EAQ90162.1 - 0.012 16.3 0.2 0.033 14.8 0.2 1.8 1 0 0 1 1 1 0 ABC-transporter N-terminal cobW PF02492.19 EAQ90162.1 - 0.026 14.1 0.1 0.047 13.3 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 EAQ90162.1 - 0.029 14.4 0.1 0.07 13.2 0.1 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase SMC_N PF02463.19 EAQ90162.1 - 0.034 13.6 0.0 0.35 10.3 0.0 2.4 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_24 PF13479.6 EAQ90162.1 - 0.048 13.4 0.1 0.28 10.9 0.0 2.2 3 0 0 3 3 2 0 AAA domain AAA_22 PF13401.6 EAQ90162.1 - 0.062 13.6 0.0 0.2 11.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EAQ90162.1 - 0.11 12.3 0.1 0.4 10.5 0.1 2.0 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.6 EAQ90162.1 - 0.11 12.1 0.1 0.34 10.4 0.1 1.8 1 0 0 1 1 1 0 AAA domain Cupin_2 PF07883.11 EAQ90163.1 - 7.2e-10 38.4 0.3 1.8e-09 37.2 0.0 1.7 2 0 0 2 2 2 1 Cupin domain Cupin_3 PF05899.12 EAQ90163.1 - 0.047 13.4 0.0 0.075 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF861) CorA PF01544.18 EAQ90165.1 - 7.4e-05 22.2 1.6 0.00026 20.4 1.6 1.8 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein MULE PF10551.9 EAQ90166.1 - 3.5e-30 104.3 1.6 4.4e-30 103.9 0.2 2.0 2 0 0 2 2 2 1 MULE transposase domain MMR_HSR1 PF01926.23 EAQ90166.1 - 1e-07 32.0 0.0 3e-07 30.5 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 EAQ90166.1 - 2e-06 27.3 0.1 7e-06 25.5 0.0 2.0 2 0 0 2 2 2 1 AIG1 family Transposase_mut PF00872.18 EAQ90166.1 - 1.9e-05 23.7 0.9 3e-05 23.0 0.0 1.7 2 0 0 2 2 2 1 Transposase, Mutator family Dynamin_N PF00350.23 EAQ90166.1 - 0.0038 17.3 0.7 2.7 8.0 0.0 2.9 1 1 1 2 2 2 2 Dynamin family FAR1 PF03101.15 EAQ90166.1 - 0.039 14.7 0.3 0.11 13.2 0.3 1.7 1 0 0 1 1 1 0 FAR1 DNA-binding domain Cellulase PF00150.18 EAQ90166.1 - 0.044 13.2 0.8 4.9 6.5 0.3 2.3 2 0 0 2 2 2 0 Cellulase (glycosyl hydrolase family 5) DUF1360 PF07098.11 EAQ90166.1 - 0.17 11.8 0.0 0.39 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1360) Abhydrolase_4 PF08386.10 EAQ90167.1 - 1.4e-16 60.5 0.0 3.4e-16 59.2 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.20 EAQ90167.1 - 2.8e-16 59.9 0.0 6.2e-07 29.3 0.0 3.2 3 0 0 3 3 3 3 alpha/beta hydrolase fold Pkinase PF00069.25 EAQ90169.1 - 2.2e-15 56.8 0.0 2.8e-15 56.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ90169.1 - 1.5e-07 31.0 0.0 2e-07 30.6 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EAQ90169.1 - 8.1e-05 22.7 0.0 0.0015 18.5 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EAQ90169.1 - 0.031 13.1 0.0 0.036 12.8 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Pox_ser-thr_kin PF05445.11 EAQ90169.1 - 0.12 11.3 0.0 0.14 11.1 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Condensation PF00668.20 EAQ90170.1 - 0 1213.0 0.0 1.3e-60 205.4 0.0 11.2 11 1 0 11 11 11 10 Condensation domain AMP-binding PF00501.28 EAQ90170.1 - 0 1078.8 2.2 1.7e-77 260.8 0.1 7.2 5 2 1 6 6 6 5 AMP-binding enzyme PP-binding PF00550.25 EAQ90170.1 - 6.4e-73 241.1 0.7 3.7e-11 43.2 0.0 7.9 7 0 0 7 7 7 6 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EAQ90170.1 - 1.9e-14 54.4 3.5 0.49 11.4 0.1 6.4 5 0 0 5 5 5 5 AMP-binding enzyme C-terminal domain Transferase PF02458.15 EAQ90170.1 - 1.1e-06 27.6 0.0 0.2 10.3 0.0 3.7 3 0 0 3 3 3 2 Transferase family DUF3658 PF12395.8 EAQ90170.1 - 0.046 13.6 0.4 15 5.6 0.0 4.4 5 0 0 5 5 5 0 Protein of unknown function RHH_3 PF12651.7 EAQ90170.1 - 0.051 13.5 0.2 1.1 9.3 0.1 2.5 2 0 0 2 2 2 0 Ribbon-helix-helix domain ABC_tran PF00005.27 EAQ90171.1 - 1.7e-40 138.7 0.3 2.2e-28 99.5 0.0 3.2 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EAQ90171.1 - 4.9e-33 114.9 16.6 5.1e-30 105.0 12.2 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.6 EAQ90171.1 - 1.9e-07 31.2 0.0 0.049 13.4 0.0 3.3 2 1 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system T2SSE PF00437.20 EAQ90171.1 - 1.4e-06 27.6 0.0 0.041 12.9 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein SMC_N PF02463.19 EAQ90171.1 - 9.2e-06 25.3 0.8 0.15 11.5 0.0 3.9 3 1 0 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EAQ90171.1 - 1.6e-05 25.2 0.6 0.048 13.9 0.0 2.8 2 1 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 EAQ90171.1 - 1.7e-05 24.8 0.1 0.0099 15.8 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 EAQ90171.1 - 4e-05 24.1 0.1 0.29 11.5 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 EAQ90171.1 - 6.9e-05 22.9 0.2 0.22 11.6 0.1 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.6 EAQ90171.1 - 7.1e-05 23.4 0.6 0.026 15.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 EAQ90171.1 - 9.7e-05 22.0 0.2 0.24 10.9 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_33 PF13671.6 EAQ90171.1 - 0.00014 22.0 0.3 0.026 14.7 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_24 PF13479.6 EAQ90171.1 - 0.00017 21.4 0.0 0.015 15.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EAQ90171.1 - 0.0002 21.0 1.1 0.095 12.5 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_25 PF13481.6 EAQ90171.1 - 0.00087 18.9 0.0 0.045 13.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 EAQ90171.1 - 0.0027 16.9 0.3 1.1 8.3 0.1 3.0 2 1 0 2 2 2 1 NB-ARC domain cobW PF02492.19 EAQ90171.1 - 0.0028 17.3 2.3 0.34 10.5 0.2 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.22 EAQ90171.1 - 0.0034 17.7 0.1 1.8 9.0 0.0 3.2 3 0 0 3 3 3 1 RNA helicase Septin PF00735.18 EAQ90171.1 - 0.0043 16.4 0.1 2.6 7.3 0.0 2.2 2 0 0 2 2 2 2 Septin FtsK_SpoIIIE PF01580.18 EAQ90171.1 - 0.0051 16.2 0.2 0.87 8.9 0.1 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family PduV-EutP PF10662.9 EAQ90171.1 - 0.0085 15.8 1.4 0.37 10.5 0.0 2.4 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Viral_helicase1 PF01443.18 EAQ90171.1 - 0.014 15.2 0.3 0.94 9.2 0.1 2.5 3 0 0 3 3 2 0 Viral (Superfamily 1) RNA helicase NACHT PF05729.12 EAQ90171.1 - 0.016 15.1 2.0 0.65 9.9 0.1 2.5 2 0 0 2 2 2 0 NACHT domain AAA PF00004.29 EAQ90171.1 - 0.017 15.5 0.1 1.8 9.0 0.0 3.0 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 EAQ90171.1 - 0.019 14.9 0.1 0.056 13.4 0.1 1.7 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_15 PF13175.6 EAQ90171.1 - 0.019 14.7 0.4 0.47 10.1 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_30 PF13604.6 EAQ90171.1 - 0.021 14.5 0.2 9.3 5.9 0.0 2.8 2 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 EAQ90171.1 - 0.023 14.0 0.2 6 6.1 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin Dynamin_N PF00350.23 EAQ90171.1 - 0.034 14.2 0.6 1.4 9.0 0.1 2.3 2 0 0 2 2 2 0 Dynamin family AAA_18 PF13238.6 EAQ90171.1 - 0.036 14.6 0.6 7.2 7.2 0.1 2.5 2 0 0 2 2 2 0 AAA domain MobB PF03205.14 EAQ90171.1 - 0.053 13.4 0.4 3.1 7.7 0.1 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 EAQ90171.1 - 0.066 13.1 1.1 5.6 6.9 0.1 2.3 2 0 0 2 2 2 0 NTPase Roc PF08477.13 EAQ90171.1 - 0.076 13.2 0.5 13 6.0 0.1 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_5 PF07728.14 EAQ90171.1 - 0.087 12.8 1.4 3.4 7.7 0.1 2.9 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 EAQ90171.1 - 0.12 11.8 0.1 1.4 8.3 0.0 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI TrwB_AAD_bind PF10412.9 EAQ90171.1 - 0.16 10.9 0.4 7 5.5 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain ATPase_2 PF01637.18 EAQ90171.1 - 0.18 11.7 0.7 4.9 7.0 0.0 2.6 3 0 0 3 3 2 0 ATPase domain predominantly from Archaea ATP_bind_1 PF03029.17 EAQ90171.1 - 0.18 11.5 0.9 13 5.5 0.1 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Adeno_IVa2 PF02456.15 EAQ90171.1 - 0.2 10.4 0.1 1.6 7.4 0.1 2.0 2 0 0 2 2 2 0 Adenovirus IVa2 protein TsaE PF02367.17 EAQ90171.1 - 0.61 10.1 1.9 19 5.3 0.0 2.6 3 0 0 3 3 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Exo_endo_phos_2 PF14529.6 EAQ90174.1 - 6.2e-16 58.3 0.0 1.6e-15 57.0 0.0 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RVT_1 PF00078.27 EAQ90174.1 - 1.5e-10 41.0 0.1 9.6e-08 31.8 0.0 2.4 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) T6SS_VipA PF05591.12 EAQ90174.1 - 0.024 14.4 0.8 0.48 10.2 1.0 2.4 2 0 0 2 2 2 0 Type VI secretion system, VipA, VC_A0107 or Hcp2 zf-RVT PF13966.6 EAQ90174.1 - 0.032 14.9 0.1 0.12 13.1 0.1 2.0 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase GCSF PF16647.5 EAQ90174.1 - 0.12 12.2 0.5 0.64 9.9 0.1 2.2 2 0 0 2 2 2 0 Granulocyte colony-stimulating factor RVT_1 PF00078.27 EAQ90175.1 - 1.4e-35 122.8 0.0 2.9e-35 121.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 EAQ90175.1 - 6e-13 48.7 0.1 2.8e-12 46.5 0.0 2.2 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase zf-RVT PF13966.6 EAQ90175.1 - 0.0074 17.0 0.2 0.057 14.1 0.0 2.6 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase DUF1043 PF06295.12 EAQ90175.1 - 0.4 10.7 6.6 1.6 8.8 6.6 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) Baculo_PEP_C PF04513.12 EAQ90175.1 - 1.1 9.3 4.2 2.9 7.9 4.2 1.7 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Prominin PF05478.11 EAQ90175.1 - 2.2 6.1 7.8 4.2 5.2 7.8 1.3 1 0 0 1 1 1 0 Prominin DUF1640 PF07798.11 EAQ90175.1 - 2.3 8.2 15.0 5.8 6.9 15.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) DUF1664 PF07889.12 EAQ90175.1 - 2.7 8.1 4.4 8.1 6.5 4.4 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Chitin_bind_1 PF00187.19 EAQ90177.1 - 4.8e-16 58.9 65.4 1.1e-06 29.0 14.9 4.5 3 2 0 3 3 3 3 Chitin recognition protein Mucin PF01456.17 EAQ90177.1 - 0.1 12.6 28.6 0.29 11.1 12.3 2.9 3 0 0 3 3 3 0 Mucin-like glycoprotein MIP PF00230.20 EAQ90178.1 - 1.1e-37 130.0 14.6 2.4e-37 128.9 14.6 1.5 1 1 0 1 1 1 1 Major intrinsic protein MFS_1 PF07690.16 EAQ90179.1 - 7.5e-48 163.2 58.5 1.4e-47 162.3 56.1 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EAQ90179.1 - 7.5e-22 77.5 26.1 9.8e-22 77.1 26.1 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EAQ90179.1 - 1.5e-12 47.1 11.5 1.5e-12 47.1 11.5 2.8 3 0 0 3 3 3 1 Sugar (and other) transporter E3_binding PF02817.17 EAQ90179.1 - 0.057 13.8 0.3 26 5.3 0.5 2.7 2 0 0 2 2 2 0 e3 binding domain Zn_clus PF00172.18 EAQ90180.1 - 9.9e-06 25.6 8.2 1.6e-05 24.9 8.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Helitron_like_N PF14214.6 EAQ90182.1 - 9.7e-39 133.6 2.5 9.7e-39 133.6 2.5 1.7 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.14 EAQ90182.1 - 4.3e-26 91.9 0.0 4.8e-22 78.6 0.0 2.5 3 0 0 3 3 3 2 PIF1-like helicase AAA_30 PF13604.6 EAQ90182.1 - 2.8e-13 50.0 0.0 6.2e-13 48.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAQ90182.1 - 7.7e-05 23.1 0.0 0.00018 21.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 EAQ90182.1 - 0.11 12.3 0.0 0.28 11.1 0.0 1.6 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Formyl_trans_N PF00551.19 EAQ90183.1 - 1.3e-34 119.5 0.1 1.7e-34 119.2 0.1 1.1 1 0 0 1 1 1 1 Formyl transferase ACT PF01842.25 EAQ90183.1 - 2.8e-07 30.2 0.0 6.9e-07 28.9 0.0 1.7 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.6 EAQ90183.1 - 0.0059 16.6 0.1 0.019 14.9 0.0 1.8 2 0 0 2 2 2 1 ACT domain RVT_1 PF00078.27 EAQ90184.1 - 2.1e-45 155.0 0.0 3.2e-45 154.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 EAQ90184.1 - 6.7e-11 42.1 0.0 1.5e-10 41.0 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 EAQ90184.1 - 5.5e-05 22.8 0.9 0.00019 21.0 0.9 2.0 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-RVT PF13966.6 EAQ90184.1 - 0.071 13.8 0.0 0.22 12.2 0.0 1.8 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase Acetyltransf_1 PF00583.25 EAQ90186.1 - 5.3e-11 42.8 0.0 7.6e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EAQ90186.1 - 1e-10 41.7 0.0 1.9e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EAQ90186.1 - 8.8e-09 35.7 0.0 2.5e-08 34.2 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EAQ90186.1 - 6.5e-05 23.0 0.1 0.00024 21.2 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EAQ90186.1 - 0.0031 17.5 0.0 0.0055 16.6 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_6 PF13480.7 EAQ90186.1 - 0.016 15.4 0.1 0.027 14.6 0.1 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain MOZ_SAS PF01853.18 EAQ90186.1 - 0.033 13.9 0.0 0.045 13.4 0.0 1.2 1 0 0 1 1 1 0 MOZ/SAS family Acetyltransf_CG PF14542.6 EAQ90186.1 - 0.082 13.1 0.0 0.19 11.9 0.0 1.5 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase Cofilin_ADF PF00241.20 EAQ90187.1 - 2.5e-09 37.0 0.3 2.3e-05 24.2 0.1 2.0 1 1 1 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein Glyco_hydro_3_C PF01915.22 EAQ90188.1 - 2.3e-43 148.6 0.0 5.5e-43 147.3 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EAQ90188.1 - 7.2e-43 147.2 0.0 1e-42 146.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EAQ90188.1 - 2.3e-21 75.7 0.5 6.1e-21 74.3 0.4 1.8 2 0 0 2 2 2 1 Fibronectin type III-like domain SSF PF00474.17 EAQ90189.1 - 1.8e-08 33.7 30.5 5.8e-08 32.0 29.1 2.3 1 1 0 1 1 1 1 Sodium:solute symporter family NDUF_B4 PF07225.12 EAQ90190.1 - 0.09 12.7 0.2 0.49 10.3 0.0 2.2 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) Phospholip_A2_3 PF09056.11 EAQ90191.1 - 2.1e-31 108.8 2.2 2.9e-29 102.0 2.2 2.1 1 1 0 1 1 1 1 Prokaryotic phospholipase A2 adh_short PF00106.25 EAQ90192.1 - 7.1e-13 48.5 0.0 1e-12 48.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EAQ90192.1 - 2.8e-09 36.9 0.0 4.1e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase RT_RNaseH PF17917.1 EAQ90193.1 - 4.5e-38 129.8 0.4 4.5e-37 126.5 0.0 2.9 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 EAQ90193.1 - 2.4e-34 117.3 0.1 1.9e-33 114.5 0.0 2.7 3 0 0 3 3 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 EAQ90193.1 - 1.2e-26 93.6 0.0 2.5e-26 92.6 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 EAQ90193.1 - 1.3e-12 48.0 0.3 5.8e-12 45.9 0.1 2.3 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 EAQ90193.1 - 7.2e-12 45.2 0.8 1.9e-11 43.9 0.0 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain Retrotrans_gag PF03732.17 EAQ90193.1 - 4.7e-09 36.4 0.4 4.7e-09 36.4 0.4 3.5 3 0 0 3 3 3 1 Retrotransposon gag protein DUF4939 PF16297.5 EAQ90193.1 - 1.5e-06 28.1 0.0 5.3e-06 26.3 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) Chromo PF00385.24 EAQ90193.1 - 3.8e-05 23.5 0.2 0.00016 21.5 0.2 2.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-CCHC PF00098.23 EAQ90193.1 - 0.00058 19.8 7.3 0.0016 18.4 7.3 1.8 1 0 0 1 1 1 1 Zinc knuckle Asp_protease_2 PF13650.6 EAQ90193.1 - 0.0018 18.9 0.0 0.0042 17.7 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 EAQ90193.1 - 0.0043 17.6 0.0 0.01 16.4 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-H2C2 PF09337.10 EAQ90193.1 - 0.017 15.3 0.0 0.056 13.7 0.0 1.9 1 0 0 1 1 1 0 H2C2 zinc finger RVP_2 PF08284.11 EAQ90193.1 - 0.027 14.3 0.0 0.054 13.3 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease PspA_IM30 PF04012.12 EAQ90193.1 - 0.043 13.4 14.8 0.056 13.0 10.9 2.7 2 0 0 2 2 2 0 PspA/IM30 family Peptidase_A2E PF12382.8 EAQ90193.1 - 0.085 12.9 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Retrotransposon peptidase Spc7 PF08317.11 EAQ90193.1 - 0.26 10.1 8.3 2.3 7.0 1.9 2.9 2 0 0 2 2 2 0 Spc7 kinetochore protein ADIP PF11559.8 EAQ90193.1 - 1.2 9.2 8.8 1 9.5 2.4 2.7 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding MscS_porin PF12795.7 EAQ90193.1 - 1.4 8.4 15.2 0.36 10.3 8.6 2.6 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain TMF_DNA_bd PF12329.8 EAQ90193.1 - 2.9 8.0 6.2 11 6.0 0.2 3.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF1664 PF07889.12 EAQ90193.1 - 4.3 7.4 5.6 7.1 6.7 0.2 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) SlyX PF04102.12 EAQ90193.1 - 6.2 7.5 9.8 26 5.5 2.1 3.8 2 0 0 2 2 2 0 SlyX Troponin PF00992.20 EAQ90193.1 - 7.3 6.9 7.8 0.31 11.3 0.4 2.6 3 0 0 3 3 1 0 Troponin Dimer_Tnp_hAT PF05699.14 EAQ90194.1 - 6.7e-13 48.2 0.1 1.6e-12 47.0 0.1 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region PIF1 PF05970.14 EAQ90195.1 - 2.9e-13 49.7 0.1 6e-06 25.7 0.0 2.9 2 1 1 3 3 3 2 PIF1-like helicase UvrD_C_2 PF13538.6 EAQ90195.1 - 0.0001 22.1 0.1 0.00048 19.9 0.0 2.1 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.14 EAQ90195.1 - 0.00037 18.6 0.0 0.002 16.2 0.0 1.8 2 0 0 2 2 2 1 Helicase DUF3638 PF12340.8 EAQ90196.1 - 3.8e-90 301.2 0.2 6.7e-90 300.4 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.8 EAQ90196.1 - 1.1e-14 53.5 0.1 2.3e-14 52.4 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) zf-CCHC PF00098.23 EAQ90197.1 - 1.4e-05 24.9 2.4 1.4e-05 24.9 2.4 1.7 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_5 PF14787.6 EAQ90197.1 - 0.00079 19.1 1.3 0.0017 18.0 1.3 1.5 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger zf-CCHC_4 PF14392.6 EAQ90197.1 - 0.034 13.9 0.3 0.074 12.8 0.3 1.6 1 0 0 1 1 1 0 Zinc knuckle FAR1 PF03101.15 EAQ90198.1 - 0.0021 18.7 0.0 0.003 18.2 0.0 1.2 1 0 0 1 1 1 1 FAR1 DNA-binding domain OrsD PF12013.8 EAQ90199.1 - 5.4e-17 62.3 0.2 7.1e-09 36.1 1.5 2.8 2 0 0 2 2 2 2 Orsellinic acid/F9775 biosynthesis cluster protein D RNase_H PF00075.24 EAQ90199.1 - 0.069 13.3 0.1 4.3 7.5 0.0 2.6 2 0 0 2 2 2 0 RNase H LRS4 PF10422.9 EAQ90199.1 - 1.1 8.8 3.6 2.1 7.8 3.6 1.4 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 SDA1 PF05285.12 EAQ90199.1 - 9 5.6 11.6 15 4.9 11.6 1.2 1 0 0 1 1 1 0 SDA1 PIF1 PF05970.14 EAQ90200.1 - 2.6e-29 102.5 0.0 1.1e-22 80.8 0.0 2.2 2 0 0 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 EAQ90200.1 - 2.9e-11 43.4 0.0 8e-11 42.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAQ90200.1 - 1e-05 25.9 0.0 2.2e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain Herpes_Helicase PF02689.14 EAQ90200.1 - 5.3e-05 21.4 0.0 0.0011 17.0 0.0 2.0 2 0 0 2 2 2 1 Helicase UvrD_C_2 PF13538.6 EAQ90200.1 - 0.00023 20.9 0.1 0.00095 18.9 0.0 2.1 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain Torsin PF06309.11 EAQ90200.1 - 0.032 14.3 0.0 0.066 13.3 0.0 1.4 1 0 0 1 1 1 0 Torsin CSS-motif PF12792.7 EAQ90201.1 - 0.05 13.1 0.4 0.16 11.4 0.4 1.9 1 0 0 1 1 1 0 CSS motif domain associated with EAL AA_permease PF00324.21 EAQ90203.1 - 1.6e-83 281.0 27.1 1.8e-83 280.7 27.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EAQ90203.1 - 2.3e-25 89.3 28.2 2.9e-25 89.0 28.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EAQ90204.1 - 3e-61 207.5 30.7 2.1e-54 185.0 21.5 2.4 2 1 1 3 3 3 2 Amino acid permease Tyrosinase PF00264.20 EAQ90204.1 - 4.3e-30 105.7 0.1 6.6e-30 105.1 0.1 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase AA_permease PF00324.21 EAQ90204.1 - 2.8e-06 26.2 22.1 2.8e-06 26.2 22.1 1.6 2 0 0 2 2 2 1 Amino acid permease Dioxygenase_C PF00775.21 EAQ90205.1 - 6.9e-09 35.4 0.0 1.1e-08 34.7 0.0 1.4 1 1 0 1 1 1 1 Dioxygenase APS_kinase PF01583.20 EAQ90205.1 - 0.0031 17.4 0.0 1.3 8.9 0.0 2.3 2 0 0 2 2 2 2 Adenylylsulphate kinase SdrD_B PF17210.3 EAQ90205.1 - 0.1 12.9 0.0 0.3 11.3 0.0 1.7 2 0 0 2 2 2 0 SdrD B-like domain S36_mt PF10937.8 EAQ90206.1 - 3.2e-42 144.7 1.0 3.8e-42 144.5 1.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S36, mitochondrial Cyto_heme_lyase PF01265.17 EAQ90207.1 - 3.7e-42 144.9 11.9 2.9e-41 142.0 11.9 2.2 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase DUF4521 PF15021.6 EAQ90207.1 - 0.15 12.0 0.6 0.25 11.2 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4521) SPX PF03105.19 EAQ90207.1 - 0.48 10.3 6.6 0.61 9.9 6.6 1.1 1 0 0 1 1 1 0 SPX domain DUF647 PF04884.14 EAQ90208.1 - 8.9e-99 330.0 0.5 1.1e-98 329.7 0.5 1.1 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis MDD_C PF18376.1 EAQ90209.1 - 7.7e-65 218.1 0.0 1.1e-64 217.7 0.0 1.2 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 EAQ90209.1 - 1.9e-08 34.4 1.9 1.9e-08 34.4 1.9 2.2 2 0 0 2 2 2 1 GHMP kinases N terminal domain E1-E2_ATPase PF00122.20 EAQ90211.1 - 1.1e-36 126.1 22.4 2.1e-32 112.1 0.1 3.3 3 1 0 4 4 4 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 EAQ90211.1 - 7.5e-20 71.4 0.0 7.5e-20 71.4 0.0 1.8 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EAQ90211.1 - 1.3e-17 64.8 0.2 3.9e-17 63.2 0.2 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EAQ90211.1 - 6.3e-15 54.6 0.0 1.7e-14 53.2 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 EAQ90211.1 - 7.4e-14 51.6 0.0 1.6e-13 50.5 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EAQ90211.1 - 9.8e-06 25.5 2.7 3e-05 23.9 1.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2463 PF09591.10 EAQ90211.1 - 0.12 12.3 1.4 0.24 11.2 1.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2463) p450 PF00067.22 EAQ90212.1 - 9.3e-45 153.2 0.0 1.3e-44 152.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_43 PF04616.14 EAQ90215.1 - 9.7e-33 113.7 0.2 1.2e-32 113.4 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 DUF5005 PF16396.5 EAQ90215.1 - 0.095 11.4 0.2 0.18 10.5 0.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5005) HET PF06985.11 EAQ90216.1 - 8.9e-27 94.2 0.1 2e-26 93.1 0.1 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Hemerythrin PF01814.23 EAQ90217.1 - 5.7e-05 23.7 2.1 8.6e-05 23.2 1.4 1.7 1 1 0 1 1 1 1 Hemerythrin HHE cation binding domain DUF4398 PF14346.6 EAQ90217.1 - 0.047 14.3 0.1 0.23 12.1 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4398) ILVD_EDD PF00920.21 EAQ90218.1 - 2.7e-155 517.9 0.4 3.1e-155 517.7 0.4 1.0 1 0 0 1 1 1 1 Dehydratase family Nucleos_tra2_C PF07662.13 EAQ90219.1 - 2e-70 236.9 0.8 2e-70 236.9 0.8 2.2 2 1 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 EAQ90219.1 - 2.5e-20 72.9 1.7 2.5e-20 72.9 1.7 3.1 4 0 0 4 4 4 1 Na+ dependent nucleoside transporter N-terminus PNK3P PF08645.11 EAQ90220.1 - 4.8e-39 133.7 0.0 8.1e-39 132.9 0.0 1.3 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.6 EAQ90220.1 - 9.3e-26 90.7 0.0 1.1e-13 51.5 0.1 2.3 1 1 1 2 2 2 2 AAA domain Zeta_toxin PF06414.12 EAQ90220.1 - 0.0086 15.4 0.0 0.55 9.5 0.0 2.1 1 1 1 2 2 2 1 Zeta toxin AAA_18 PF13238.6 EAQ90220.1 - 0.031 14.8 0.2 4.6 7.8 0.0 2.4 1 1 1 2 2 2 0 AAA domain AAA_22 PF13401.6 EAQ90220.1 - 0.063 13.6 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EAQ90220.1 - 0.07 13.5 0.0 0.11 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Sugar_tr PF00083.24 EAQ90221.1 - 1.5e-113 380.1 22.4 1.7e-113 379.9 22.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EAQ90221.1 - 6e-28 97.8 37.0 6.4e-28 97.7 32.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_5 PF05631.14 EAQ90221.1 - 0.00057 18.9 0.5 0.00057 18.9 0.5 1.8 2 0 0 2 2 2 1 Sugar-tranasporters, 12 TM Phage_holin_2_3 PF16080.5 EAQ90221.1 - 0.31 10.8 2.2 0.49 10.2 0.2 2.4 2 0 0 2 2 2 0 Bacteriophage holin family HP1 Selenoprotein_S PF06936.11 EAQ90222.1 - 0.014 15.2 1.5 0.019 14.8 1.5 1.2 1 0 0 1 1 1 0 Selenoprotein S (SelS) RuvA_C PF07499.13 EAQ90222.1 - 0.12 12.8 0.7 0.22 12.0 0.1 1.8 2 0 0 2 2 2 0 RuvA, C-terminal domain adh_short PF00106.25 EAQ90223.1 - 5.2e-28 97.8 0.0 1.4e-19 70.3 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EAQ90223.1 - 4.5e-17 62.4 0.0 3.5e-12 46.4 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EAQ90223.1 - 0.00026 21.0 0.4 0.00049 20.1 0.3 1.4 1 1 0 1 1 1 1 KR domain Toprim_3 PF13362.6 EAQ90223.1 - 0.018 15.4 0.3 0.15 12.4 0.3 2.2 2 0 0 2 2 2 0 Toprim domain Sacchrp_dh_NADP PF03435.18 EAQ90223.1 - 0.049 13.9 0.1 0.089 13.0 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Polysacc_synt_2 PF02719.15 EAQ90223.1 - 0.067 12.3 0.0 0.091 11.9 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Shikimate_DH PF01488.20 EAQ90223.1 - 0.084 12.9 0.5 0.72 9.9 0.1 2.1 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase Glyco_tran_WecB PF03808.13 EAQ90223.1 - 0.2 11.6 0.0 0.29 11.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family MCU PF04678.13 EAQ90224.1 - 1.3e-23 84.0 0.2 1.3e-23 84.0 0.2 2.0 2 0 0 2 2 2 1 Mitochondrial calcium uniporter Herpes_DNAp_acc PF04929.12 EAQ90224.1 - 4.2 6.3 4.2 10 5.0 4.2 1.6 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Acetyltransf_8 PF13523.6 EAQ90225.1 - 4.2e-36 123.8 0.2 6.6e-36 123.2 0.2 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain NAD_binding_11 PF14833.6 EAQ90227.1 - 0.00016 21.9 0.0 0.00025 21.3 0.0 1.2 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase BNR_3 PF13859.6 EAQ90228.1 - 4.2e-09 36.1 0.0 5.2e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 BNR repeat-like domain BNR_2 PF13088.6 EAQ90228.1 - 2.1e-07 30.6 0.1 4e-05 23.1 0.1 3.5 1 1 1 2 2 2 2 BNR repeat-like domain BNR PF02012.20 EAQ90228.1 - 0.00049 19.7 5.9 0.22 11.6 0.1 3.1 2 0 0 2 2 2 2 BNR/Asp-box repeat DUF4185 PF13810.6 EAQ90228.1 - 0.012 14.9 0.2 1.4 8.0 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4185) Sortilin-Vps10 PF15902.5 EAQ90228.1 - 0.083 11.7 0.0 0.12 11.2 0.0 1.4 1 0 0 1 1 1 0 Sortilin, neurotensin receptor 3, Ribosomal_L37ae PF01780.19 EAQ90229.1 - 0.15 12.2 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 Ribosomal L37ae protein family Glyco_hydro_76 PF03663.14 EAQ90230.1 - 4.4e-151 503.5 2.4 5.1e-151 503.3 2.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Gcd10p PF04189.13 EAQ90231.1 - 2.6e-109 365.0 0.0 3.5e-109 364.6 0.0 1.1 1 0 0 1 1 1 1 Gcd10p family dCache_1 PF02743.18 EAQ90231.1 - 0.14 11.9 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 Cache domain P21-Arc PF04062.14 EAQ90232.1 - 5.9e-71 238.1 0.0 6.9e-71 237.9 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit DUF1974 PF09317.11 EAQ90232.1 - 0.17 11.4 0.1 0.43 10.1 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1974) COesterase PF00135.28 EAQ90234.1 - 2.8e-88 297.0 0.0 3.8e-88 296.6 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EAQ90234.1 - 0.016 15.1 0.4 0.03 14.2 0.0 1.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EAQ90234.1 - 0.043 13.3 0.9 0.15 11.5 0.8 1.8 2 0 0 2 2 2 0 Prolyl oligopeptidase family NAD_binding_10 PF13460.6 EAQ90235.1 - 1.7e-09 37.9 0.0 2e-09 37.6 0.0 1.0 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EAQ90235.1 - 0.00014 21.5 0.0 0.00016 21.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 EAQ90235.1 - 0.017 14.6 0.0 0.04 13.4 0.0 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Asp PF00026.23 EAQ90236.1 - 2.4e-47 161.9 0.9 4.2e-42 144.7 0.9 2.1 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EAQ90236.1 - 1e-09 38.9 3.4 7.9e-08 32.7 0.2 3.3 3 1 0 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EAQ90236.1 - 0.017 15.7 0.1 0.53 11.0 0.0 2.8 3 0 0 3 3 3 0 Aspartyl protease gag-asp_proteas PF13975.6 EAQ90236.1 - 0.096 13.3 0.0 14 6.3 0.0 2.7 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 EAQ90236.1 - 0.16 11.7 0.0 5.1 6.9 0.0 2.2 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal MULE PF10551.9 EAQ90237.1 - 5.2e-25 87.7 0.0 9.4e-25 86.9 0.0 1.4 1 0 0 1 1 1 1 MULE transposase domain ADSL_C PF10397.9 EAQ90238.1 - 0.11 13.0 0.0 0.46 11.1 0.0 2.1 1 1 0 1 1 1 0 Adenylosuccinate lyase C-terminus Transglut_core PF01841.19 EAQ90239.1 - 1.7e-09 38.1 0.6 1.7e-08 34.9 0.6 2.4 2 0 0 2 2 2 1 Transglutaminase-like superfamily Rad4 PF03835.15 EAQ90239.1 - 3.1e-08 33.4 0.2 6.4e-08 32.4 0.2 1.5 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BIR PF00653.21 EAQ90239.1 - 0.021 15.5 0.1 0.42 11.3 0.0 2.7 2 0 0 2 2 2 0 Inhibitor of Apoptosis domain HeLo PF14479.6 EAQ90239.1 - 0.1 12.4 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 Prion-inhibition and propagation zf-C2H2_4 PF13894.6 EAQ90239.1 - 0.15 12.9 6.6 4.5 8.4 0.1 4.9 4 0 0 4 4 4 0 C2H2-type zinc finger WAC_Acf1_DNA_bd PF10537.9 EAQ90239.1 - 0.16 12.5 0.0 0.47 11.0 0.0 1.7 1 0 0 1 1 1 0 ATP-utilising chromatin assembly and remodelling N-terminal SRCR_2 PF15494.6 EAQ90239.1 - 0.23 12.0 1.6 4.4 7.9 0.5 2.7 2 0 0 2 2 2 0 Scavenger receptor cysteine-rich domain DUF1996 PF09362.10 EAQ90241.1 - 6.4e-51 173.6 3.0 7.5e-51 173.4 3.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Glyco_hydro_43 PF04616.14 EAQ90242.1 - 6e-11 42.2 3.4 1.1e-10 41.3 3.4 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Peptidase_S8 PF00082.22 EAQ90244.1 - 6.7e-07 28.8 0.0 5.1e-06 26.0 0.0 2.0 1 1 0 1 1 1 1 Subtilase family Annexin PF00191.20 EAQ90245.1 - 5.4e-09 36.0 2.7 0.026 14.6 0.0 4.4 4 0 0 4 4 4 2 Annexin zf-Di19 PF05605.12 EAQ90245.1 - 0.05 13.9 0.7 0.05 13.9 0.7 3.2 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.6 EAQ90245.1 - 8.5 7.0 12.6 1.7 9.2 0.1 4.2 3 1 0 3 3 3 0 Zinc-finger double domain Pro-kuma_activ PF09286.11 EAQ90246.1 - 1.9e-20 73.6 0.3 1.9e-11 44.4 0.2 2.4 1 1 1 2 2 2 2 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 EAQ90246.1 - 0.00085 18.7 0.0 0.0016 17.8 0.0 1.4 1 0 0 1 1 1 1 Subtilase family Alpha-amylase PF00128.24 EAQ90247.1 - 6.6e-23 81.8 0.1 6.4e-20 72.0 0.0 2.4 2 1 0 2 2 2 2 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.11 EAQ90247.1 - 9.9e-17 61.4 0.1 1.7e-16 60.7 0.1 1.3 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 EAQ90247.1 - 7.5e-07 28.8 0.0 1.4e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EAQ90247.1 - 0.012 15.7 0.0 0.035 14.1 0.0 1.8 1 0 0 1 1 1 0 Glycosyltransferase Family 4 VCBS PF13517.6 EAQ90247.1 - 0.15 12.7 0.5 0.69 10.6 0.5 2.3 1 0 0 1 1 1 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella SKG6 PF08693.10 EAQ90247.1 - 2 7.9 4.7 6.7 6.2 4.7 1.9 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Alpha-amylase PF00128.24 EAQ90248.1 - 2.4e-50 172.0 0.2 3.3e-50 171.5 0.2 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.11 EAQ90248.1 - 1.9e-28 98.6 1.0 3.7e-28 97.6 1.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) DUF3914 PF13053.6 EAQ90248.1 - 0.077 13.3 0.0 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3914) Helo_like_N PF17111.5 EAQ90249.1 - 8.4e-08 31.8 0.1 1.5e-07 31.0 0.1 1.4 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins SesA PF17107.5 EAQ90249.1 - 0.00087 19.5 0.4 0.0029 17.8 0.0 2.0 2 0 0 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases FAD_binding_2 PF00890.24 EAQ90250.1 - 2.1e-90 303.8 0.3 2.4e-90 303.6 0.3 1.0 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EAQ90250.1 - 9.2e-07 29.0 0.2 3.6e-06 27.1 0.0 2.1 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EAQ90250.1 - 3e-05 23.4 2.0 0.00072 18.9 0.0 3.1 3 1 1 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EAQ90250.1 - 6.9e-05 22.2 0.0 0.00013 21.4 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 EAQ90250.1 - 0.00013 21.7 0.2 0.00059 19.5 0.0 2.2 3 0 0 3 3 3 1 FAD dependent oxidoreductase GIDA PF01134.22 EAQ90250.1 - 0.00014 21.0 0.1 0.00014 21.0 0.1 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.17 EAQ90250.1 - 0.00042 19.6 0.0 0.00095 18.5 0.0 1.5 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 EAQ90250.1 - 0.00043 19.1 3.2 0.004 15.9 0.1 2.3 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 EAQ90250.1 - 0.0026 17.2 0.0 0.0044 16.4 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EAQ90250.1 - 0.0075 15.5 0.0 0.014 14.7 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EAQ90250.1 - 0.13 12.2 0.0 0.33 10.9 0.0 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 EAQ90250.1 - 0.63 9.0 2.3 0.48 9.4 0.2 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein FAD-oxidase_C PF02913.19 EAQ90251.1 - 1.8e-60 204.7 0.5 2.7e-60 204.1 0.5 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 EAQ90251.1 - 6.7e-40 136.0 0.0 1.2e-39 135.2 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Y_phosphatase3 PF13350.6 EAQ90252.1 - 9.1e-43 146.9 0.0 1.1e-42 146.6 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 EAQ90252.1 - 0.00012 21.7 0.0 0.00018 21.2 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.13 EAQ90252.1 - 0.0094 15.5 0.0 0.023 14.3 0.0 1.7 2 0 0 2 2 2 1 Tyrosine phosphatase family Myotub-related PF06602.14 EAQ90252.1 - 0.024 13.6 0.0 0.035 13.0 0.0 1.2 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain PTPlike_phytase PF14566.6 EAQ90252.1 - 0.084 13.0 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 Inositol hexakisphosphate DSPc PF00782.20 EAQ90252.1 - 0.1 12.4 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain ATG7_N PF16420.5 EAQ90252.1 - 0.24 11.0 0.0 0.29 10.7 0.0 1.1 1 0 0 1 1 1 0 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus Oxysterol_BP PF01237.18 EAQ90253.1 - 4.8e-50 170.5 0.0 5e-47 160.5 0.0 2.1 1 1 0 1 1 1 1 Oxysterol-binding protein Sugar_tr PF00083.24 EAQ90254.1 - 8.6e-100 334.7 15.6 9.9e-100 334.5 15.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EAQ90254.1 - 3e-30 105.3 26.1 1.9e-21 76.4 7.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Alpha-L-AF_C PF06964.12 EAQ90255.1 - 8.5e-31 107.3 0.1 1.6e-30 106.4 0.1 1.4 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain Glyco_hydro_44 PF12891.7 EAQ90255.1 - 0.053 13.5 1.5 0.12 12.2 1.5 1.6 1 1 0 1 1 1 0 Glycoside hydrolase family 44 Ank_2 PF12796.7 EAQ90257.1 - 8.2e-17 61.6 0.1 1.4e-06 28.8 0.1 3.6 3 1 2 5 5 5 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAQ90257.1 - 1.6e-07 31.1 0.1 0.00084 19.6 0.0 4.8 5 0 0 5 5 5 1 Ankyrin repeat Ank_5 PF13857.6 EAQ90257.1 - 4.2e-06 26.9 0.1 1.1e-05 25.6 0.1 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAQ90257.1 - 8.1e-05 23.1 0.0 0.00026 21.5 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 EAQ90257.1 - 0.0012 19.2 0.0 0.16 12.5 0.0 3.6 3 0 0 3 3 3 1 Ankyrin repeat Fungal_trans PF04082.18 EAQ90258.1 - 2e-07 30.3 0.1 3.3e-07 29.6 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.25 EAQ90259.1 - 4e-23 81.9 0.1 5.2e-23 81.5 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EAQ90259.1 - 1.3e-11 44.5 0.0 1.6e-11 44.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EAQ90259.1 - 6.4e-11 42.5 0.1 8e-11 42.2 0.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EAQ90259.1 - 6.9e-05 22.4 0.0 7.9e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EAQ90259.1 - 0.013 14.9 0.0 0.015 14.7 0.0 1.1 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EAQ90259.1 - 0.059 12.5 0.1 0.066 12.3 0.1 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 EAQ90259.1 - 0.083 12.0 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain NAD_binding_4 PF07993.12 EAQ90259.1 - 0.1 11.7 0.3 0.17 11.0 0.3 1.3 1 1 0 1 1 1 0 Male sterility protein Shikimate_DH PF01488.20 EAQ90259.1 - 0.16 12.0 0.3 0.35 10.9 0.2 1.6 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ANAPC4_WD40 PF12894.7 EAQ90260.1 - 2.7e-08 34.0 0.0 0.39 11.0 0.0 5.1 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EAQ90260.1 - 0.15 13.0 4.5 16 6.6 0.0 5.8 7 1 1 8 8 8 0 WD domain, G-beta repeat NACHT PF05729.12 EAQ90261.1 - 0.042 13.8 0.0 0.065 13.2 0.0 1.3 1 0 0 1 1 1 0 NACHT domain APS_kinase PF01583.20 EAQ90261.1 - 0.046 13.6 0.0 0.076 12.9 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase 6PF2K PF01591.18 EAQ90261.1 - 0.066 12.5 0.0 0.098 12.0 0.0 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase DUF2075 PF09848.9 EAQ90261.1 - 0.077 12.2 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.22 EAQ90261.1 - 0.13 12.7 0.0 0.32 11.4 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_19 PF13245.6 EAQ90261.1 - 0.19 12.0 0.0 0.7 10.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain Fructosamin_kin PF03881.14 EAQ90262.1 - 1e-19 70.8 0.0 1.3e-19 70.5 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 EAQ90262.1 - 0.0021 18.0 0.1 0.0028 17.6 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Sugar_tr PF00083.24 EAQ90263.1 - 1.6e-102 343.7 31.5 2.1e-102 343.3 31.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EAQ90263.1 - 1.5e-24 86.6 37.2 3.6e-22 78.8 20.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Pkinase PF00069.25 EAQ90264.1 - 3.7e-06 26.5 0.0 6.3e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 EAQ90264.1 - 0.0034 17.3 0.6 0.006 16.5 0.2 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EAQ90264.1 - 0.0088 15.4 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Ank_4 PF13637.6 EAQ90266.1 - 6e-24 84.1 6.0 1.1e-10 41.8 0.0 3.0 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAQ90266.1 - 8.4e-24 84.0 0.1 2.3e-17 63.4 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAQ90266.1 - 1.9e-21 75.9 8.6 1.3e-07 31.7 0.9 3.9 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 EAQ90266.1 - 2.1e-17 62.7 2.3 0.0015 18.9 0.1 4.4 4 0 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.6 EAQ90266.1 - 2.2e-17 61.3 1.8 0.0024 18.2 0.0 4.4 4 0 0 4 4 4 4 Ankyrin repeat bZIP_1 PF00170.21 EAQ90266.1 - 0.00037 20.5 1.3 0.00063 19.8 1.3 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 EAQ90266.1 - 0.0078 16.7 0.5 0.014 15.9 0.5 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor adh_short PF00106.25 EAQ90267.1 - 4.5e-22 78.5 0.0 8.2e-22 77.6 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EAQ90267.1 - 8e-16 58.3 0.0 1.3e-15 57.7 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EAQ90267.1 - 7.6e-12 45.5 0.0 1.3e-11 44.7 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EAQ90267.1 - 6.7e-08 32.3 0.0 1.2e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EAQ90267.1 - 8.8e-06 25.3 0.0 1.6e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EAQ90267.1 - 0.00021 21.3 0.4 0.00034 20.5 0.4 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EAQ90267.1 - 0.017 14.6 0.1 0.025 14.1 0.1 1.3 1 0 0 1 1 1 0 NmrA-like family RVT_1 PF00078.27 EAQ90268.1 - 1.1e-40 139.5 0.0 1.7e-40 138.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 EAQ90268.1 - 0.00015 21.5 0.0 0.0003 20.6 0.0 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RecC_C PF17946.1 EAQ90268.1 - 0.0057 16.5 5.4 0.47 10.2 0.5 3.2 3 0 0 3 3 3 2 RecC C-terminal domain Pkinase PF00069.25 EAQ90269.1 - 6.8e-08 32.2 0.0 1.3e-07 31.3 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Kdo PF06293.14 EAQ90269.1 - 0.00084 18.8 0.0 0.0013 18.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family WaaY PF06176.11 EAQ90269.1 - 0.0052 16.4 0.0 0.009 15.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) APH PF01636.23 EAQ90269.1 - 0.061 13.2 0.2 0.1 12.5 0.2 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 EAQ90269.1 - 0.073 12.3 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase FAD_binding_3 PF01494.19 EAQ90270.1 - 2.7e-15 56.5 0.2 1.5e-07 31.0 0.0 2.9 3 0 0 3 3 3 2 FAD binding domain DAO PF01266.24 EAQ90270.1 - 0.00066 19.4 0.1 0.0095 15.6 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EAQ90270.1 - 0.0016 17.6 0.5 0.0041 16.2 0.3 1.7 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 EAQ90270.1 - 0.0083 15.4 0.1 0.018 14.3 0.1 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EAQ90270.1 - 0.027 14.7 0.0 0.072 13.3 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EAQ90270.1 - 0.12 11.0 0.1 0.17 10.5 0.1 1.1 1 0 0 1 1 1 0 HI0933-like protein MFS_1 PF07690.16 EAQ90271.1 - 6.6e-36 124.0 46.0 6.6e-36 124.0 46.0 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EAQ90271.1 - 5.1e-07 28.9 28.2 4.5e-06 25.8 27.6 2.5 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 EAQ90271.1 - 0.0001 20.9 5.5 0.00016 20.3 5.5 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 EAQ90271.1 - 1 7.6 8.8 4.2 5.5 8.5 2.1 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Fungal_trans PF04082.18 EAQ90272.1 - 7.8e-11 41.5 0.0 1.5e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EAQ90272.1 - 2.6e-05 24.2 1.4 2.6e-05 24.2 1.4 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cytochrom_NNT PF03264.14 EAQ90272.1 - 0.095 12.4 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 NapC/NirT cytochrome c family, N-terminal region RVT_1 PF00078.27 EAQ90273.1 - 7.1e-41 140.1 0.0 6.7e-40 137.0 0.0 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) NDC10_II PF16787.5 EAQ90274.1 - 1.9e-102 342.6 0.0 2.8e-102 342.0 0.0 1.2 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 AAA_22 PF13401.6 EAQ90277.1 - 0.0017 18.7 0.0 0.0038 17.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 EAQ90277.1 - 0.01 15.8 0.1 0.05 13.5 0.1 2.2 1 1 0 1 1 1 0 NACHT domain AAA_18 PF13238.6 EAQ90277.1 - 0.019 15.5 0.0 0.076 13.6 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EAQ90277.1 - 0.028 14.8 0.0 0.055 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain ATPase PF06745.13 EAQ90277.1 - 0.031 13.6 0.0 0.062 12.6 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_29 PF13555.6 EAQ90277.1 - 0.032 14.0 0.1 0.11 12.2 0.1 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATPase_2 PF01637.18 EAQ90277.1 - 0.036 14.0 0.0 0.099 12.5 0.0 1.7 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_24 PF13479.6 EAQ90277.1 - 0.081 12.6 0.1 0.16 11.7 0.1 1.6 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EAQ90277.1 - 0.13 12.6 0.0 0.39 11.1 0.0 1.8 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.27 EAQ90277.1 - 0.15 12.6 0.0 0.38 11.3 0.0 1.6 1 0 0 1 1 1 0 ABC transporter Ank_2 PF12796.7 EAQ90278.1 - 9.5e-37 125.5 0.5 4.5e-07 30.4 0.1 9.7 7 2 0 8 8 8 6 Ankyrin repeats (3 copies) Cellulase PF00150.18 EAQ90278.1 - 1.2e-32 113.4 0.2 2e-32 112.7 0.2 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Ank_4 PF13637.6 EAQ90278.1 - 3.8e-30 103.9 11.4 3e-06 27.7 0.1 9.8 11 0 0 11 11 11 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAQ90278.1 - 5e-24 84.1 20.8 0.0017 18.6 0.0 10.5 9 1 1 10 10 10 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAQ90278.1 - 3.2e-22 76.2 16.3 0.0044 17.4 0.0 12.4 14 0 0 14 14 14 5 Ankyrin repeat Ank PF00023.30 EAQ90278.1 - 5.9e-19 67.6 17.0 4.1e-05 23.8 0.0 12.9 14 0 0 14 14 14 2 Ankyrin repeat TPR_19 PF14559.6 EAQ90278.1 - 0.0096 16.4 1.6 0.19 12.3 0.1 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat Hexapep_2 PF14602.6 EAQ90278.1 - 0.074 12.8 0.2 0.17 11.6 0.2 1.6 1 0 0 1 1 1 0 Hexapeptide repeat of succinyl-transferase Fringe PF02434.16 EAQ90279.1 - 0.00052 19.5 2.7 0.0033 16.9 2.7 2.0 1 1 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 EAQ90279.1 - 0.045 13.6 0.3 0.11 12.2 0.3 1.7 1 1 0 1 1 1 0 Galactosyltransferase DUF2165 PF09933.9 EAQ90280.1 - 0.0054 16.8 0.0 0.0086 16.1 0.0 1.2 1 0 0 1 1 1 1 Predicted small integral membrane protein (DUF2165) Tcp11 PF05794.13 EAQ90281.1 - 2.9e-103 346.3 0.1 2.9e-103 346.3 0.1 1.8 2 0 0 2 2 2 1 T-complex protein 11 UPF0242 PF06785.11 EAQ90281.1 - 0.27 11.3 12.2 0.2 11.7 6.3 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF3433 PF11915.8 EAQ90282.1 - 5.8e-10 39.5 2.7 5.8e-10 39.5 2.7 2.4 4 0 0 4 4 4 1 Protein of unknown function (DUF3433) Innate_immun PF12782.7 EAQ90282.1 - 0.14 11.6 1.0 0.23 11.0 1.0 1.2 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family Peptidase_M1 PF01433.20 EAQ90283.1 - 2.3e-81 272.6 3.1 3.3e-81 272.0 3.1 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 EAQ90283.1 - 4.1e-77 259.8 0.0 5.7e-76 256.1 0.0 2.1 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 EAQ90283.1 - 2.5e-48 164.7 0.2 6.8e-47 160.1 0.0 2.2 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain DUF45 PF01863.17 EAQ90283.1 - 0.0034 17.5 0.0 0.0091 16.1 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function DUF45 Peptidase_M50 PF02163.22 EAQ90283.1 - 0.097 11.9 0.0 0.2 10.9 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M50 SprT-like PF10263.9 EAQ90283.1 - 0.18 11.7 0.0 0.42 10.5 0.0 1.6 1 0 0 1 1 1 0 SprT-like family Torus PF16131.5 EAQ90284.1 - 1.8e-14 54.4 12.5 0.00024 21.8 0.8 3.6 2 1 1 3 3 3 3 Torus domain zf_CCCH_4 PF18345.1 EAQ90284.1 - 2.4e-12 46.5 29.9 7.9e-05 22.6 6.0 3.8 3 0 0 3 3 3 3 Zinc finger domain zf-CCCH PF00642.24 EAQ90284.1 - 9e-11 41.4 22.6 1.9e-05 24.4 0.7 3.5 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) IBR PF01485.21 EAQ90284.1 - 1.1e-07 32.0 7.5 9.8e-06 25.7 6.8 3.0 2 0 0 2 2 2 1 IBR domain, a half RING-finger domain zf-CCCH_4 PF18044.1 EAQ90284.1 - 1.2e-07 31.4 20.8 0.00095 18.9 3.0 3.6 3 0 0 3 3 3 3 CCCH-type zinc finger zf-CCCH_3 PF15663.5 EAQ90284.1 - 0.0013 18.9 8.3 1.8 8.8 0.1 3.6 3 0 0 3 3 3 2 Zinc-finger containing family zf-CCCH_2 PF14608.6 EAQ90284.1 - 0.0025 18.2 24.1 0.1 13.1 4.2 3.9 3 0 0 3 3 3 3 RNA-binding, Nab2-type zinc finger Ank_2 PF12796.7 EAQ90285.1 - 1.8e-51 172.7 4.7 2.6e-16 59.9 0.4 3.4 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAQ90285.1 - 2.4e-33 114.1 1.9 2.6e-09 37.4 0.0 5.9 3 1 4 7 7 7 5 Ankyrin repeats (many copies) Ank PF00023.30 EAQ90285.1 - 4.5e-33 112.2 0.2 7e-06 26.3 0.1 5.8 5 0 0 5 5 5 5 Ankyrin repeat Ank_3 PF13606.6 EAQ90285.1 - 2.2e-30 101.3 0.0 0.00024 21.3 0.0 7.2 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 EAQ90285.1 - 9.1e-26 89.6 0.4 5.4e-09 36.2 0.0 4.3 1 1 3 4 4 4 4 Ankyrin repeats (many copies) GATase_7 PF13537.6 EAQ90285.1 - 0.022 14.6 0.0 11 5.9 0.0 3.4 2 2 1 3 3 3 0 Glutamine amidotransferase domain tRNA-synt_His PF13393.6 EAQ90286.1 - 7e-33 114.2 0.0 4.4e-32 111.6 0.0 1.9 1 1 0 1 1 1 1 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 EAQ90286.1 - 3.7e-09 36.6 0.3 1.1e-08 35.1 0.1 1.9 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2 PF00152.20 EAQ90286.1 - 0.0059 15.7 0.0 0.051 12.6 0.0 2.1 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) HGTP_anticodon2 PF12745.7 EAQ90286.1 - 0.041 13.4 0.0 0.061 12.8 0.0 1.2 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs DUF1479 PF07350.12 EAQ90288.1 - 2.9e-163 543.5 0.0 3.6e-163 543.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) IDO PF01231.18 EAQ90289.1 - 8.3e-08 31.4 0.0 4e-07 29.2 0.0 1.9 1 1 0 1 1 1 1 Indoleamine 2,3-dioxygenase adh_short PF00106.25 EAQ90291.1 - 1.6e-20 73.4 0.0 2e-20 73.1 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EAQ90291.1 - 6.2e-17 61.9 0.1 8e-17 61.6 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EAQ90291.1 - 1.4e-10 41.3 0.0 1.9e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EAQ90291.1 - 2e-06 27.5 0.0 2.6e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EAQ90291.1 - 0.00013 21.9 0.8 0.00025 21.0 0.8 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 EAQ90291.1 - 0.00065 20.0 0.2 0.0025 18.1 0.1 1.8 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain VWA PF00092.28 EAQ90291.1 - 0.086 13.1 0.0 0.97 9.7 0.0 2.1 2 0 0 2 2 2 0 von Willebrand factor type A domain MFS_1 PF07690.16 EAQ90292.1 - 1e-18 67.4 28.2 3.6e-10 39.3 13.8 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily zf-RVT PF13966.6 EAQ90295.1 - 0.06 14.1 0.0 0.15 12.8 0.0 1.7 2 0 0 2 2 2 0 zinc-binding in reverse transcriptase MFS_1 PF07690.16 EAQ90297.1 - 2.2e-32 112.3 23.7 2.2e-32 112.3 23.7 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Abhydrolase_4 PF08386.10 EAQ90300.1 - 7.8e-16 58.1 0.0 1.3e-15 57.3 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.20 EAQ90300.1 - 1.1e-10 41.7 0.1 5.3e-09 36.1 0.1 2.2 2 1 0 2 2 2 2 alpha/beta hydrolase fold Fungal_trans_2 PF11951.8 EAQ90301.1 - 0.0014 17.5 0.1 0.0024 16.8 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ank_2 PF12796.7 EAQ90302.1 - 1.1e-45 154.2 7.6 3.2e-15 56.5 0.2 3.4 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) NACHT_N PF17100.5 EAQ90302.1 - 9.9e-35 120.4 0.0 3e-34 118.8 0.0 1.8 1 0 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase MULE PF10551.9 EAQ90302.1 - 6.9e-24 84.1 0.4 1.7e-23 82.9 0.0 1.9 2 0 0 2 2 2 1 MULE transposase domain Ank PF00023.30 EAQ90302.1 - 5.4e-23 80.4 0.1 0.00014 22.2 0.0 5.7 5 0 0 5 5 5 5 Ankyrin repeat Ank_3 PF13606.6 EAQ90302.1 - 3.3e-20 70.0 0.0 0.0056 17.1 0.0 5.7 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 EAQ90302.1 - 5.8e-19 68.2 0.2 3.7e-05 24.2 0.0 4.8 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAQ90302.1 - 1.4e-16 60.3 0.3 9.5e-07 29.0 0.0 4.0 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Transposase_mut PF00872.18 EAQ90302.1 - 0.0067 15.3 0.0 0.016 14.1 0.0 1.5 1 0 0 1 1 1 1 Transposase, Mutator family DUF5575 PF17738.1 EAQ90302.1 - 0.12 11.4 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5575) Trypan_PARP PF05887.11 EAQ90302.1 - 0.31 11.0 3.0 0.71 9.9 3.0 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MFS_1 PF07690.16 EAQ90303.1 - 5.8e-29 101.1 27.3 5.8e-29 101.1 27.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily COX14 PF14880.6 EAQ90303.1 - 0.045 13.6 0.1 0.28 11.1 0.0 2.3 2 0 0 2 2 2 0 Cytochrome oxidase c assembly Phage_holin_2_4 PF16082.5 EAQ90303.1 - 0.08 12.7 0.2 22 4.9 0.0 2.8 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like DUF1129 PF06570.11 EAQ90303.1 - 0.6 9.6 2.7 0.74 9.3 0.0 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1129) GFO_IDH_MocA_C PF02894.17 EAQ90304.1 - 2.3e-17 63.0 0.1 7.1e-17 61.5 0.1 1.8 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain FA_hydroxylase PF04116.13 EAQ90305.1 - 1.2e-21 77.5 16.5 1.2e-21 77.5 16.5 2.0 2 1 1 3 3 3 1 Fatty acid hydroxylase superfamily V_ATPase_I PF01496.19 EAQ90307.1 - 0.29 9.0 1.7 0.32 8.9 1.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SelP_N PF04592.14 EAQ90307.1 - 0.78 9.1 12.4 0.95 8.8 12.4 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region zf-RVT PF13966.6 EAQ90309.1 - 0.13 13.0 0.7 0.4 11.4 0.1 2.2 2 1 0 2 2 2 0 zinc-binding in reverse transcriptase FAD_binding_3 PF01494.19 EAQ90310.1 - 0.002 17.4 0.0 0.0026 17.1 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DUF3429 PF11911.8 EAQ90312.1 - 1.7e-38 132.2 5.8 2.2e-38 131.8 5.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) Neur_chan_memb PF02932.16 EAQ90312.1 - 4.2 7.4 5.6 6.9 6.7 5.6 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SHR-BD PF06650.12 EAQ90313.1 - 9.4e-95 317.0 0.0 2.3e-92 309.2 0.0 2.6 2 0 0 2 2 2 2 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13_mid_rpt PF16910.5 EAQ90313.1 - 1.7e-92 309.1 14.9 1.2e-89 299.8 3.8 5.5 5 1 1 6 6 6 2 Repeating coiled region of VPS13 VPS13 PF16908.5 EAQ90313.1 - 5.2e-87 291.6 0.6 1.1e-84 283.9 0.0 3.4 4 0 0 4 4 4 1 Vacuolar sorting-associated protein 13, N-terminal VPS13_C PF16909.5 EAQ90313.1 - 4e-76 254.8 6.0 8.5e-71 237.4 0.6 2.6 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal Chorein_N PF12624.7 EAQ90313.1 - 5.5e-40 136.1 0.0 2e-39 134.3 0.0 2.1 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 EAQ90313.1 - 8.1e-08 32.5 0.3 5.4e-07 29.9 0.0 2.5 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain AP4E_app_platf PF14807.6 EAQ90313.1 - 0.072 13.5 0.1 0.43 11.0 0.1 2.4 2 0 0 2 2 2 0 Adaptin AP4 complex epsilon appendage platform Methyltransf_23 PF13489.6 EAQ90314.1 - 3.3e-12 46.5 0.0 5.8e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EAQ90314.1 - 1.2e-11 45.1 0.0 3.6e-11 43.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAQ90314.1 - 2.1e-09 38.0 0.0 1.4e-08 35.3 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EAQ90314.1 - 2.7e-05 24.8 0.0 0.00036 21.2 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EAQ90314.1 - 0.00047 19.6 0.0 0.00076 18.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 EAQ90314.1 - 0.0031 17.3 0.0 0.008 16.0 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_8 PF05148.15 EAQ90314.1 - 0.029 14.2 0.0 1.5 8.6 0.0 2.3 2 0 0 2 2 2 0 Hypothetical methyltransferase AMP-binding PF00501.28 EAQ90316.1 - 7.6e-198 657.3 0.0 1.3e-69 234.8 0.0 3.3 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.20 EAQ90316.1 - 2e-70 237.8 0.0 4.4e-19 68.5 0.0 6.8 5 2 0 5 5 5 5 Condensation domain PP-binding PF00550.25 EAQ90316.1 - 1e-35 121.9 0.4 2.8e-09 37.2 0.0 6.0 6 0 0 6 6 6 5 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EAQ90316.1 - 1e-12 48.9 1.0 2.1e-05 25.4 0.0 4.2 4 0 0 4 4 4 2 AMP-binding enzyme C-terminal domain WES_acyltransf PF03007.16 EAQ90316.1 - 0.0047 16.7 0.8 2.3 7.9 0.0 4.2 4 0 0 4 4 4 1 Wax ester synthase-like Acyl-CoA acyltransferase domain Transferase PF02458.15 EAQ90316.1 - 0.046 12.4 0.1 11 4.5 0.0 3.1 4 0 0 4 4 4 0 Transferase family Acetyltransf_8 PF13523.6 EAQ90317.1 - 6.3e-25 87.6 0.3 1.1e-24 86.8 0.3 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain ABC_membrane PF00664.23 EAQ90318.1 - 6.9e-55 186.6 15.6 2.1e-32 112.9 3.4 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EAQ90318.1 - 5.9e-48 162.9 0.0 2.7e-31 108.9 0.1 2.5 2 0 0 2 2 2 2 ABC transporter FAD_binding_3 PF01494.19 EAQ90318.1 - 2.1e-20 73.3 0.0 1.7e-19 70.3 0.0 2.1 1 1 0 1 1 1 1 FAD binding domain SMC_N PF02463.19 EAQ90318.1 - 5e-12 45.7 1.4 0.0012 18.3 0.0 4.1 2 2 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EAQ90318.1 - 1.4e-07 31.6 0.0 0.057 13.2 0.0 3.6 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 EAQ90318.1 - 1.1e-06 28.8 0.2 0.016 15.3 0.1 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_7 PF12775.7 EAQ90318.1 - 2.3e-06 27.2 0.0 0.0075 15.8 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_16 PF13191.6 EAQ90318.1 - 0.00015 22.2 0.3 0.04 14.3 0.1 2.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 EAQ90318.1 - 0.00022 21.8 0.0 0.55 10.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 EAQ90318.1 - 0.00029 20.5 0.1 0.093 12.5 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain NAD_binding_8 PF13450.6 EAQ90318.1 - 0.0019 18.4 0.7 0.0063 16.7 0.7 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Dynamin_N PF00350.23 EAQ90318.1 - 0.0025 17.9 0.1 1.2 9.2 0.0 2.5 2 0 0 2 2 2 1 Dynamin family AAA_22 PF13401.6 EAQ90318.1 - 0.0034 17.7 1.4 1.5 9.1 0.8 3.3 2 1 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EAQ90318.1 - 0.004 17.1 0.0 1.7 8.5 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase Zeta_toxin PF06414.12 EAQ90318.1 - 0.011 15.0 0.1 0.61 9.3 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin DUF87 PF01935.17 EAQ90318.1 - 0.016 15.3 0.2 0.03 14.4 0.2 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain T2SSE PF00437.20 EAQ90318.1 - 0.016 14.3 0.1 0.14 11.2 0.1 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein Trp_halogenase PF04820.14 EAQ90318.1 - 0.017 14.0 0.2 0.045 12.6 0.2 1.7 1 0 0 1 1 1 0 Tryptophan halogenase DAO PF01266.24 EAQ90318.1 - 0.03 13.9 1.6 0.07 12.7 1.6 1.6 1 0 0 1 1 1 0 FAD dependent oxidoreductase AAA_18 PF13238.6 EAQ90318.1 - 0.038 14.6 0.0 17 5.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.9 EAQ90318.1 - 0.041 12.8 0.1 0.32 9.8 0.2 2.1 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Pes-10 PF07149.11 EAQ90318.1 - 0.073 12.1 0.1 0.13 11.3 0.1 1.3 1 0 0 1 1 1 0 Pes-10 AAA_15 PF13175.6 EAQ90318.1 - 0.081 12.6 0.0 9.5 5.8 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_33 PF13671.6 EAQ90318.1 - 0.081 13.1 0.1 21 5.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EAQ90318.1 - 0.083 12.6 0.9 1.7 8.3 0.2 2.9 3 0 0 3 3 3 0 AAA domain FAD_binding_2 PF00890.24 EAQ90318.1 - 0.095 11.8 0.6 0.18 10.8 0.6 1.4 1 0 0 1 1 1 0 FAD binding domain TsaE PF02367.17 EAQ90318.1 - 0.11 12.6 0.0 4.4 7.3 0.1 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA PF00004.29 EAQ90318.1 - 0.11 12.9 0.4 33 4.9 0.0 3.4 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 EAQ90318.1 - 0.11 12.1 0.2 0.71 9.4 0.1 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Roc PF08477.13 EAQ90318.1 - 0.21 11.8 0.7 4.7 7.5 0.1 2.8 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase SbcCD_C PF13558.6 EAQ90318.1 - 0.22 11.8 1.3 51 4.2 0.3 3.7 3 1 0 3 3 3 0 Putative exonuclease SbcCD, C subunit MFS_1 PF07690.16 EAQ90319.1 - 7e-15 54.8 46.5 9.8e-14 51.0 46.5 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily HET PF06985.11 EAQ90321.1 - 1.4e-11 44.9 2.8 6.9e-09 36.2 0.2 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) APT PF03440.14 EAQ90321.1 - 0.047 13.7 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 Aerolysin/Pertussis toxin (APT) domain Aldo_ket_red PF00248.21 EAQ90322.1 - 3.6e-22 78.9 0.0 4.6e-22 78.6 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family RVT_1 PF00078.27 EAQ90323.1 - 9.7e-33 113.5 0.0 5.5e-32 111.1 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 EAQ90323.1 - 3.7e-20 72.0 1.4 6.3e-20 71.2 0.6 1.8 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase PIF1 PF05970.14 EAQ90323.1 - 7.3e-11 41.8 0.0 1.4e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 PIF1-like helicase Exo_endo_phos PF03372.23 EAQ90323.1 - 0.00059 19.4 0.4 0.0013 18.3 0.4 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family CbtB PF09489.10 EAQ90326.1 - 0.1 12.7 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtB) Sugar_tr PF00083.24 EAQ90327.1 - 1.3e-119 400.0 27.2 1.5e-119 399.9 27.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EAQ90327.1 - 1.7e-19 70.0 51.0 4.1e-15 55.6 31.5 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily TPR_19 PF14559.6 EAQ90327.1 - 0.081 13.4 0.0 0.17 12.4 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat WD40 PF00400.32 EAQ90328.1 - 2.9e-13 50.0 20.1 0.034 15.0 0.0 9.1 8 0 0 8 8 8 4 WD domain, G-beta repeat NACHT PF05729.12 EAQ90328.1 - 1.1e-09 38.4 0.0 2.6e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 NACHT domain ANAPC4_WD40 PF12894.7 EAQ90328.1 - 1.8e-08 34.6 0.4 0.06 13.6 0.0 5.6 3 1 3 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain AAA_16 PF13191.6 EAQ90328.1 - 0.00011 22.6 0.0 0.00054 20.4 0.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain PD40 PF07676.12 EAQ90328.1 - 0.00024 20.9 3.3 28 4.8 0.0 6.2 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat AAA_19 PF13245.6 EAQ90328.1 - 0.0027 18.0 0.0 0.008 16.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain DUF2793 PF10983.8 EAQ90328.1 - 0.068 13.0 1.1 1.2 9.1 0.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2793) TerB PF05099.13 EAQ90328.1 - 0.069 13.1 0.1 0.14 12.2 0.1 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TerB AAA_22 PF13401.6 EAQ90328.1 - 0.099 12.9 0.0 0.39 11.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain PRAS PF15798.5 EAQ90328.1 - 0.15 12.6 0.0 7.9 7.1 0.0 2.6 2 0 0 2 2 2 0 Proline-rich AKT1 substrate 1 RNA_helicase PF00910.22 EAQ90328.1 - 0.15 12.5 0.0 0.31 11.5 0.0 1.5 1 0 0 1 1 1 0 RNA helicase APG6_N PF17675.1 EAQ90329.1 - 1.3e-05 25.7 47.7 0.1 13.2 2.2 4.3 1 1 3 4 4 4 3 Apg6 coiled-coil region DUF1664 PF07889.12 EAQ90329.1 - 0.0011 19.0 1.1 0.0011 19.0 1.1 3.6 1 1 2 3 3 3 1 Protein of unknown function (DUF1664) GAS PF13851.6 EAQ90329.1 - 0.0024 17.2 36.9 0.0033 16.8 0.5 3.3 1 1 2 3 3 3 2 Growth-arrest specific micro-tubule binding BRE1 PF08647.11 EAQ90329.1 - 0.0027 17.7 38.6 0.009 16.1 7.2 4.6 1 1 4 5 5 5 2 BRE1 E3 ubiquitin ligase PI3K_P85_iSH2 PF16454.5 EAQ90329.1 - 0.008 15.8 20.9 3.1 7.4 3.4 3.9 1 1 2 3 3 3 3 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain ERM PF00769.19 EAQ90329.1 - 0.017 15.0 48.6 0.24 11.2 28.3 3.0 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Matrilin_ccoil PF10393.9 EAQ90329.1 - 0.023 14.6 0.2 0.023 14.6 0.2 2.5 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin MqsA_antitoxin PF15731.5 EAQ90329.1 - 0.036 14.2 1.3 0.18 11.9 0.2 2.5 1 1 1 2 2 2 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA UPF0242 PF06785.11 EAQ90329.1 - 0.24 11.5 29.9 0.21 11.7 3.6 3.2 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus CENP-F_leu_zip PF10473.9 EAQ90329.1 - 0.26 11.3 36.7 0.64 10.0 5.0 4.3 1 1 1 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.11 EAQ90329.1 - 0.58 9.0 37.5 0.74 8.6 11.7 3.2 1 1 1 3 3 3 0 Spc7 kinetochore protein Mce4_CUP1 PF11887.8 EAQ90329.1 - 0.66 9.4 13.1 3 7.2 4.5 2.2 1 1 1 2 2 2 0 Cholesterol uptake porter CUP1 of Mce4, putative Filament PF00038.21 EAQ90329.1 - 0.83 9.2 33.1 1.1 8.7 22.3 3.3 1 1 1 2 2 2 0 Intermediate filament protein COG6 PF06419.11 EAQ90329.1 - 0.97 7.6 12.0 0.11 10.7 2.2 2.3 1 1 1 2 2 2 0 Conserved oligomeric complex COG6 Prominin PF05478.11 EAQ90329.1 - 1 7.2 6.8 1.3 6.9 6.3 1.3 1 1 0 1 1 1 0 Prominin LPP PF04728.13 EAQ90329.1 - 1.1 9.8 0.1 1.1 9.8 0.1 4.5 3 2 0 3 3 3 0 Lipoprotein leucine-zipper DUF724 PF05266.14 EAQ90329.1 - 2 8.2 29.1 0.13 12.1 5.5 3.3 1 1 1 3 3 3 0 Protein of unknown function (DUF724) Tektin PF03148.14 EAQ90329.1 - 2.3 6.9 31.8 0.21 10.3 1.1 4.7 1 1 2 5 5 5 0 Tektin family MCC-bdg_PDZ PF10506.9 EAQ90329.1 - 3.6 7.7 10.5 20 5.3 0.5 3.7 2 1 1 3 3 3 0 PDZ domain of MCC-2 bdg protein for Usher syndrome KASH_CCD PF14662.6 EAQ90329.1 - 3.6 7.4 33.0 1.6 8.5 22.5 3.2 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH GIT_CC PF16559.5 EAQ90329.1 - 6.5 6.7 9.5 6.1 6.8 0.2 4.0 3 1 1 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor NACHT PF05729.12 EAQ90331.1 - 1.2e-05 25.3 0.0 3e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 NACHT domain DUF676 PF05057.14 EAQ90331.1 - 0.00012 21.6 0.0 0.00024 20.7 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) AAA_22 PF13401.6 EAQ90331.1 - 0.00039 20.7 0.0 0.0011 19.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain PGAP1 PF07819.13 EAQ90331.1 - 0.015 15.0 0.0 0.033 13.9 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_6 PF12697.7 EAQ90331.1 - 0.018 15.7 0.0 0.094 13.3 0.0 2.3 2 1 0 2 2 2 0 Alpha/beta hydrolase family Lipase_3 PF01764.25 EAQ90331.1 - 0.04 13.8 0.0 0.13 12.1 0.0 1.8 2 0 0 2 2 2 0 Lipase (class 3) DUF2791 PF10923.8 EAQ90331.1 - 0.053 12.4 0.0 0.28 10.0 0.0 2.0 2 0 0 2 2 2 0 P-loop Domain of unknown function (DUF2791) Lipase_2 PF01674.18 EAQ90331.1 - 0.084 12.4 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Lipase (class 2) IstB_IS21 PF01695.17 EAQ90331.1 - 0.16 11.7 0.0 0.39 10.4 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein Alg14 PF08660.11 EAQ90332.1 - 1.2 9.0 4.4 2.9 7.8 0.1 2.6 2 1 1 3 3 3 0 Oligosaccharide biosynthesis protein Alg14 like DUF1484 PF07363.11 EAQ90332.1 - 1.4 9.9 0.0 1.4 9.9 0.0 3.7 4 1 0 4 4 4 0 Protein of unknown function (DUF1484) RVT_2 PF07727.14 EAQ90333.1 - 1.3e-33 116.7 0.0 2.8e-33 115.6 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 EAQ90333.1 - 3.9e-09 36.7 0.0 1.1e-08 35.3 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.6 EAQ90333.1 - 2.9e-06 27.0 0.0 5.2e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 GAG-pre-integrase domain Phg_2220_C PF09524.10 EAQ90334.1 - 0.08 13.0 0.0 20 5.3 0.0 2.5 2 0 0 2 2 2 0 Conserved phage C-terminus (Phg_2220_C) Dimer_Tnp_hAT PF05699.14 EAQ90335.1 - 0.00018 21.2 0.0 0.00042 20.0 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Peptidase_M14 PF00246.24 EAQ90337.1 - 7.6e-65 219.6 0.1 9.2e-65 219.3 0.1 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.16 EAQ90337.1 - 1.3e-06 28.7 0.0 5.7e-06 26.6 0.0 2.0 2 0 0 2 2 2 1 Carboxypeptidase activation peptide ABA_WDS PF02496.16 EAQ90338.1 - 0.14 12.6 8.7 0.68 10.5 1.0 4.0 2 1 0 2 2 2 0 ABA/WDS induced protein F-box-like PF12937.7 EAQ90339.1 - 4.2e-05 23.3 0.4 0.00011 22.0 0.4 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EAQ90339.1 - 0.0012 18.6 2.1 0.024 14.5 2.1 2.6 1 1 0 1 1 1 1 F-box domain Prenyltrans PF00432.21 EAQ90339.1 - 0.014 15.1 0.2 0.029 14.1 0.2 1.5 1 0 0 1 1 1 0 Prenyltransferase and squalene oxidase repeat LtrA PF06772.11 EAQ90340.1 - 6.1e-30 104.6 18.3 6.1e-30 104.6 18.3 1.9 2 0 0 2 2 2 1 Bacterial low temperature requirement A protein (LtrA) DUF3328 PF11807.8 EAQ90341.1 - 0.00015 21.6 0.5 0.00024 21.0 0.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) WD40 PF00400.32 EAQ90343.1 - 4.5e-54 179.2 15.6 1.7e-08 35.0 0.6 8.7 8 1 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAQ90343.1 - 2.3e-10 40.6 0.1 0.0085 16.4 0.0 4.4 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EAQ90343.1 - 1e-08 34.3 0.5 0.00022 20.1 0.0 4.3 5 0 0 5 5 5 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 EAQ90343.1 - 8.2e-06 24.8 0.1 0.0068 15.2 0.0 3.1 3 0 0 3 3 3 2 Nup133 N terminal like VID27 PF08553.10 EAQ90343.1 - 0.22 10.6 0.0 5.2 6.0 0.0 2.1 2 0 0 2 2 2 0 VID27 C-terminal WD40-like domain CLASP_N PF12348.8 EAQ90344.1 - 3.5e-05 23.5 0.1 7.8e-05 22.3 0.1 1.5 1 0 0 1 1 1 1 CLASP N terminal TAN PF11640.8 EAQ90344.1 - 0.00069 19.8 0.3 0.00069 19.8 0.3 2.0 2 0 0 2 2 2 1 Telomere-length maintenance and DNA damage repair Cnd1 PF12717.7 EAQ90344.1 - 0.0011 19.0 0.2 0.0023 18.0 0.2 1.6 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 Syntaxin PF00804.25 EAQ90344.1 - 0.016 14.9 3.2 0.019 14.7 1.5 2.0 2 0 0 2 2 2 0 Syntaxin HEAT PF02985.22 EAQ90344.1 - 0.15 12.4 4.2 14 6.2 0.3 5.0 5 0 0 5 5 5 0 HEAT repeat CCDC144C PF14915.6 EAQ90344.1 - 0.33 10.0 9.2 0.68 9.0 9.2 1.4 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region ADIP PF11559.8 EAQ90344.1 - 0.86 9.7 10.9 2.4 8.2 10.9 1.7 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding NYD-SP28_assoc PF14775.6 EAQ90344.1 - 1.2 9.3 3.7 1.4 9.1 0.6 2.6 2 1 0 2 2 2 0 Sperm tail C-terminal domain SHE3 PF17078.5 EAQ90344.1 - 2.1 8.0 9.7 4.4 7.0 9.7 1.4 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 Cep57_CLD_2 PF14197.6 EAQ90344.1 - 2.9 8.1 16.1 6.8 6.9 2.5 2.7 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 HALZ PF02183.18 EAQ90344.1 - 5.8 7.2 11.8 15 5.9 0.5 3.5 3 1 0 3 3 3 0 Homeobox associated leucine zipper Metallophos PF00149.28 EAQ90345.1 - 3.3e-10 40.8 0.6 4.4e-10 40.4 0.6 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF4868 PF16162.5 EAQ90345.1 - 0.078 12.9 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4868) Amidase PF01425.21 EAQ90346.1 - 5.7e-15 55.2 4.2 5.6e-14 51.9 4.5 2.1 2 1 0 2 2 2 1 Amidase Cytomega_UL84 PF06284.11 EAQ90346.1 - 0.0018 16.9 0.2 0.0024 16.4 0.2 1.1 1 0 0 1 1 1 1 Cytomegalovirus UL84 protein Condensation PF00668.20 EAQ90348.1 - 1.2e-83 281.4 0.0 3.3e-31 108.5 0.0 3.5 3 1 0 3 3 3 3 Condensation domain AMP-binding PF00501.28 EAQ90348.1 - 1e-33 116.6 0.0 1.7e-33 115.8 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 EAQ90348.1 - 1.6e-22 79.6 1.3 2.7e-09 37.2 0.2 4.8 5 0 0 5 5 5 3 Phosphopantetheine attachment site TAL_effector PF03377.13 EAQ90348.1 - 0.039 14.3 0.0 0.67 10.3 0.0 2.6 2 0 0 2 2 2 0 TAL effector repeat Beta-lactamase PF00144.24 EAQ90349.1 - 4.1e-18 65.7 0.0 1.5e-09 37.5 0.0 2.2 1 1 0 2 2 2 2 Beta-lactamase DUF3471 PF11954.8 EAQ90349.1 - 2.3e-10 40.9 0.0 4.1e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) SET PF00856.28 EAQ90350.1 - 5.4e-05 23.6 0.0 0.00013 22.4 0.0 1.7 2 0 0 2 2 2 1 SET domain HCO3_cotransp PF00955.21 EAQ90351.1 - 2.7e-62 211.2 14.5 6.9e-31 107.6 7.6 2.8 1 1 1 2 2 2 2 HCO3- transporter family Glyco_hydro_32N PF00251.20 EAQ90352.1 - 7.2e-75 252.4 2.8 9.4e-75 252.0 2.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 EAQ90352.1 - 2.2e-06 27.8 0.0 4e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal FXa_inhibition PF14670.6 EAQ90353.1 - 1.9 8.8 7.5 0.52 10.6 0.4 2.8 2 1 1 3 3 3 0 Coagulation Factor Xa inhibitory site Pectate_lyase PF03211.13 EAQ90354.1 - 1.3e-60 204.4 3.0 5.3e-50 169.8 0.3 2.0 2 0 0 2 2 2 2 Pectate lyase Cu-oxidase_2 PF07731.14 EAQ90355.1 - 1.7e-43 147.7 9.8 3.3e-39 133.8 0.2 3.2 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 EAQ90355.1 - 1.7e-39 134.5 7.9 1.1e-38 131.9 3.0 3.5 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.22 EAQ90355.1 - 9.9e-35 120.0 0.2 2e-34 119.0 0.2 1.6 1 0 0 1 1 1 1 Multicopper oxidase F-box-like PF12937.7 EAQ90356.1 - 0.044 13.7 0.1 0.13 12.2 0.1 1.9 1 0 0 1 1 1 0 F-box-like Ysc84 PF04366.12 EAQ90357.1 - 1.4e-51 173.5 0.0 3.2e-51 172.4 0.0 1.6 1 0 0 1 1 1 1 Las17-binding protein actin regulator VIT1 PF01988.19 EAQ90360.1 - 4.4e-72 242.4 1.7 5.1e-72 242.2 1.7 1.0 1 0 0 1 1 1 1 VIT family Orai-1 PF07856.12 EAQ90360.1 - 0.088 12.5 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Mediator of CRAC channel activity SLATT_fungal PF18142.1 EAQ90360.1 - 0.28 11.2 1.4 3.3 7.7 0.0 2.5 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain Periviscerokin PF08259.11 EAQ90360.1 - 7.9 7.1 6.4 11 6.7 0.8 3.1 2 0 0 2 2 2 0 Periviscerokinin family DDE_1 PF03184.19 EAQ90363.1 - 2.9e-24 85.7 0.1 4.4e-23 81.8 0.1 2.2 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 EAQ90363.1 - 9.6e-10 38.4 0.0 3.4e-09 36.6 0.0 2.0 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.16 EAQ90363.1 - 3.2e-06 26.8 0.0 7e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 helix-turn-helix, Psq domain DDE_3 PF13358.6 EAQ90363.1 - 0.0011 18.7 0.1 0.0026 17.5 0.1 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease YlqD PF11068.8 EAQ90363.1 - 0.062 13.7 7.5 0.14 12.6 7.5 1.5 1 0 0 1 1 1 0 YlqD protein Phage_lysozyme2 PF18013.1 EAQ90363.1 - 0.3 11.1 2.5 0.85 9.6 1.3 2.3 2 0 0 2 2 2 0 Phage tail lysozyme DUF4200 PF13863.6 EAQ90363.1 - 0.63 10.5 10.2 1.2 9.5 10.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Amidoligase_2 PF12224.8 EAQ90364.1 - 1.7e-62 211.4 0.4 2.1e-62 211.1 0.4 1.1 1 0 0 1 1 1 1 Putative amidoligase enzyme Methyltransf_2 PF00891.18 EAQ90365.1 - 2.4e-24 85.8 0.0 3.6e-24 85.2 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_31 PF13847.6 EAQ90365.1 - 0.0005 19.9 0.0 0.043 13.6 0.0 2.5 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 EAQ90365.1 - 0.05 14.3 0.1 0.23 12.2 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain FtsJ PF01728.19 EAQ90365.1 - 0.15 12.2 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase AMP-binding PF00501.28 EAQ90367.1 - 8.6e-53 179.4 0.0 1.4e-52 178.7 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Thioesterase PF00975.20 EAQ90367.1 - 3.1e-24 86.4 0.0 2.1e-23 83.6 0.0 2.0 1 1 0 1 1 1 1 Thioesterase domain PP-binding PF00550.25 EAQ90367.1 - 2.4e-11 43.8 0.0 1.5e-10 41.2 0.0 2.3 2 0 0 2 2 2 1 Phosphopantetheine attachment site Abhydrolase_1 PF00561.20 EAQ90367.1 - 2.9e-05 23.8 0.0 4.7e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EAQ90367.1 - 0.00014 21.2 0.0 0.00027 20.3 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EAQ90367.1 - 0.038 14.6 10.7 0.021 15.4 6.9 2.5 2 0 0 2 2 2 0 Alpha/beta hydrolase family Methyltransf_2 PF00891.18 EAQ90368.1 - 2.3e-14 53.2 0.0 1.7e-09 37.3 0.0 2.2 2 0 0 2 2 2 2 O-methyltransferase domain Dimerisation PF08100.11 EAQ90368.1 - 6.1e-05 23.0 0.6 0.00018 21.4 0.2 2.1 2 0 0 2 2 2 1 Dimerisation domain Dimerisation2 PF16864.5 EAQ90368.1 - 0.0076 16.2 0.1 0.019 15.0 0.1 1.6 1 0 0 1 1 1 1 Dimerisation domain TrmB PF01978.19 EAQ90368.1 - 0.01 15.7 0.1 0.043 13.7 0.1 2.0 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB HTH_IclR PF09339.10 EAQ90368.1 - 0.013 15.3 1.5 0.033 14.0 0.1 2.3 2 0 0 2 2 2 0 IclR helix-turn-helix domain Rrf2 PF02082.20 EAQ90368.1 - 0.099 13.0 0.1 0.3 11.4 0.0 1.8 2 0 0 2 2 2 0 Transcriptional regulator MarR_2 PF12802.7 EAQ90368.1 - 0.14 12.1 0.1 0.31 11.0 0.1 1.5 1 0 0 1 1 1 0 MarR family Glyco_hydro_61 PF03443.14 EAQ90369.1 - 4.9e-39 134.4 0.0 9e-39 133.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 NmrA PF05368.13 EAQ90369.1 - 1.6e-26 93.3 0.0 8.1e-14 51.7 0.0 2.2 2 0 0 2 2 2 2 NmrA-like family NAD_binding_10 PF13460.6 EAQ90369.1 - 7.9e-14 52.0 0.0 1.3e-13 51.2 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding zf-3CxxC PF13695.6 EAQ90369.1 - 9.7e-11 42.0 0.1 2.2e-10 40.9 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding domain Epimerase PF01370.21 EAQ90369.1 - 0.0013 18.3 0.0 0.0023 17.5 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EAQ90369.1 - 0.1 12.0 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase BPS1 PF05633.11 EAQ90369.1 - 0.14 11.2 0.1 0.2 10.7 0.1 1.1 1 0 0 1 1 1 0 Protein BYPASS1-related p450 PF00067.22 EAQ90370.1 - 4.8e-50 170.6 0.0 7e-50 170.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF485 PF04341.12 EAQ90371.1 - 0.11 12.5 0.4 0.11 12.5 0.4 3.1 3 0 0 3 3 3 0 Protein of unknown function, DUF485 Wzy_C PF04932.15 EAQ90371.1 - 1.6 8.4 8.7 0.24 11.0 0.2 2.6 3 0 0 3 3 3 0 O-Antigen ligase MFS_1 PF07690.16 EAQ90372.1 - 3.1e-23 82.3 41.7 5.4e-23 81.5 38.2 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EAQ90372.1 - 2e-13 49.6 6.8 2e-13 49.6 6.8 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EAQ90372.1 - 7.1e-07 28.4 10.2 7.1e-07 28.4 10.2 2.8 2 1 1 3 3 3 1 Sugar (and other) transporter TssN PF17555.2 EAQ90372.1 - 2 7.7 4.1 5.7 6.2 4.1 1.7 1 1 0 1 1 1 0 Type VI secretion system, TssN p450 PF00067.22 EAQ90373.1 - 5.1e-18 65.1 0.0 1.6e-17 63.5 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 BRO1 PF03097.18 EAQ90375.1 - 6.6e-108 361.0 0.4 2.4e-106 355.9 0.4 2.3 1 1 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 EAQ90375.1 - 1.1e-71 241.5 3.4 1.1e-71 241.5 3.4 2.0 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV Phage_GP20 PF06810.11 EAQ90375.1 - 0.035 13.9 1.3 0.24 11.2 0.5 2.3 2 0 0 2 2 2 0 Phage minor structural protein GP20 SlyX PF04102.12 EAQ90375.1 - 0.63 10.7 2.7 17 6.1 0.4 3.6 3 0 0 3 3 3 0 SlyX DUF4666 PF15697.5 EAQ90375.1 - 0.83 10.4 3.6 0.42 11.3 0.9 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4666) LprI PF07007.12 EAQ90375.1 - 1.8 9.3 6.2 4 8.1 3.5 2.9 2 1 0 2 2 2 0 Lysozyme inhibitor LprI p450 PF00067.22 EAQ90377.1 - 2.3e-57 194.8 0.1 6.2e-45 153.8 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 AAA_16 PF13191.6 EAQ90378.1 - 8e-08 32.8 0.8 7.2e-07 29.7 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 EAQ90378.1 - 6.7e-05 22.9 0.1 0.00017 21.5 0.1 1.7 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 EAQ90378.1 - 0.0031 17.8 0.0 0.011 16.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain Orbi_VP2 PF00898.17 EAQ90378.1 - 0.0094 13.8 1.1 0.014 13.2 1.1 1.1 1 0 0 1 1 1 1 Orbivirus outer capsid protein VP2 cobW PF02492.19 EAQ90378.1 - 0.032 13.8 0.0 0.068 12.8 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain SesA PF17107.5 EAQ90378.1 - 0.033 14.4 0.0 0.15 12.3 0.0 2.2 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases AAA_18 PF13238.6 EAQ90378.1 - 0.035 14.7 0.0 0.088 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EAQ90378.1 - 0.19 11.5 0.1 0.43 10.4 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 EAQ90378.1 - 0.23 12.0 0.5 0.57 10.7 0.0 1.9 2 0 0 2 2 2 0 ABC transporter AAA_11 PF13086.6 EAQ90378.1 - 0.33 10.7 4.4 1.3 8.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain NADH_u_ox_C PF12853.7 EAQ90379.1 - 0.23 11.4 0.0 0.45 10.5 0.0 1.4 1 0 0 1 1 1 0 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit ADH_zinc_N PF00107.26 EAQ90380.1 - 1e-21 77.2 0.1 1.6e-21 76.6 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EAQ90380.1 - 3.1e-20 72.1 0.1 5.8e-20 71.2 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 EAQ90380.1 - 9.8e-08 31.7 0.5 2.1e-07 30.6 0.5 1.5 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 EAQ90380.1 - 1.8e-07 32.3 0.0 4e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_31 PF13847.6 EAQ90380.1 - 0.035 13.9 0.0 0.066 13.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 EAQ90380.1 - 0.048 13.2 0.0 0.078 12.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain AlaDh_PNT_C PF01262.21 EAQ90380.1 - 0.072 12.4 2.0 0.089 12.1 0.8 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain MFS_1 PF07690.16 EAQ90381.1 - 3.5e-19 68.9 25.5 3.5e-19 68.9 25.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EAQ90381.1 - 6.9e-05 21.9 6.1 6.9e-05 21.9 6.1 2.8 2 1 1 3 3 3 2 Sugar (and other) transporter Glyco_hydro_127 PF07944.12 EAQ90382.1 - 1e-16 60.5 0.0 1.4e-16 60.1 0.0 1.1 1 0 0 1 1 1 1 Beta-L-arabinofuranosidase, GH127 TPR_12 PF13424.6 EAQ90384.1 - 9.6e-36 121.9 8.8 9.3e-11 41.9 0.3 4.1 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.6 EAQ90384.1 - 3.6e-35 118.9 0.7 8.6e-15 54.1 0.0 4.9 4 0 0 4 4 4 3 Tetratricopeptide repeat NB-ARC PF00931.22 EAQ90384.1 - 5.7e-07 29.0 0.0 1.1e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain TPR_1 PF00515.28 EAQ90384.1 - 8.6e-07 28.5 3.2 0.019 14.8 0.1 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 EAQ90384.1 - 4.8e-05 23.1 1.8 0.18 11.9 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 EAQ90384.1 - 7.9e-05 22.6 4.2 0.28 11.5 0.1 4.2 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EAQ90384.1 - 0.0012 18.8 0.2 0.58 10.4 0.1 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat AAA_16 PF13191.6 EAQ90384.1 - 0.012 16.0 0.6 0.19 12.1 0.3 3.0 3 1 0 3 3 2 0 AAA ATPase domain TPR_6 PF13174.6 EAQ90384.1 - 0.018 15.6 0.8 2 9.2 0.2 3.9 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 EAQ90384.1 - 0.023 15.3 0.0 24 5.7 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 EAQ90384.1 - 0.043 14.3 0.5 14 6.3 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 EAQ90384.1 - 0.074 13.7 0.0 16 6.5 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 EAQ90384.1 - 0.13 12.7 0.0 1.3 9.5 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat ATP-synt_C PF00137.21 EAQ90385.1 - 6.2e-12 45.7 2.3 8.1e-12 45.3 2.1 1.3 1 1 0 1 1 1 1 ATP synthase subunit C Alpha-amylase PF00128.24 EAQ90386.1 - 4.6e-17 62.6 0.0 2.2e-16 60.4 0.0 1.8 1 1 0 1 1 1 1 Alpha amylase, catalytic domain DUF1939 PF09154.10 EAQ90386.1 - 0.019 15.2 0.2 0.046 13.9 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1939) Ferric_reduct PF01794.19 EAQ90388.1 - 7.2e-15 55.2 10.9 7.2e-15 55.2 10.9 1.8 1 1 0 1 1 1 1 Ferric reductase like transmembrane component DUF4405 PF14358.6 EAQ90388.1 - 0.9 10.1 12.8 3.6 8.2 4.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4405) Band_7 PF01145.25 EAQ90390.1 - 4.1e-14 53.0 0.1 4.1e-14 53.0 0.1 3.1 2 2 0 2 2 2 1 SPFH domain / Band 7 family DUF3986 PF13143.6 EAQ90390.1 - 0.018 16.0 0.2 7.9 7.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3986) zf-C2H2 PF00096.26 EAQ90391.1 - 0.00025 21.3 8.3 0.014 15.8 0.7 3.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EAQ90391.1 - 0.03 15.1 13.2 0.39 11.7 0.3 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger MFS_1 PF07690.16 EAQ90392.1 - 2.2e-10 40.0 0.1 2.2e-10 40.0 0.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Fructosamin_kin PF03881.14 EAQ90393.1 - 4.7e-36 124.5 0.0 5.8e-36 124.2 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 EAQ90393.1 - 2.7e-05 24.2 0.0 5.5e-05 23.2 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family ANAPC4_WD40 PF12894.7 EAQ90394.1 - 1e-05 25.8 0.0 0.058 13.7 0.0 2.9 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain PGAP1 PF07819.13 EAQ90394.1 - 8.5e-05 22.4 0.1 0.0003 20.6 0.1 1.9 1 1 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.14 EAQ90394.1 - 0.0016 18.0 0.1 0.0079 15.7 0.0 2.0 2 0 0 2 2 2 1 Putative serine esterase (DUF676) AAA_16 PF13191.6 EAQ90394.1 - 0.003 18.0 0.0 0.0087 16.5 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain Abhydrolase_6 PF12697.7 EAQ90394.1 - 0.012 16.2 0.2 0.084 13.5 0.0 2.6 2 0 0 2 2 2 0 Alpha/beta hydrolase family NACHT PF05729.12 EAQ90394.1 - 0.025 14.5 0.0 0.066 13.1 0.0 1.7 1 0 0 1 1 1 0 NACHT domain Abhydrolase_1 PF00561.20 EAQ90394.1 - 0.029 14.0 0.0 0.078 12.6 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold FAD_binding_4 PF01565.23 EAQ90395.1 - 1.2e-26 93.1 4.2 1.9e-26 92.4 4.2 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EAQ90395.1 - 1.3e-11 44.4 0.2 3.5e-11 43.0 0.2 1.8 1 0 0 1 1 1 1 Berberine and berberine like stn_TNFRSF12A PF12191.8 EAQ90396.1 - 0.18 12.1 4.5 1.5 9.0 0.2 2.8 2 0 0 2 2 2 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain DoxX_3 PF13781.6 EAQ90396.1 - 0.88 10.2 11.1 3 8.6 0.2 3.0 3 0 0 3 3 3 0 DoxX-like family Pkinase PF00069.25 EAQ90397.1 - 2.7e-11 43.3 0.0 4.5e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ90397.1 - 4.8e-10 39.2 0.0 1.3e-08 34.5 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EAQ90397.1 - 0.0013 18.2 0.0 0.0022 17.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4678 PF15727.5 EAQ90397.1 - 0.24 10.7 0.3 0.35 10.1 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4678) DLH PF01738.18 EAQ90398.1 - 8.8e-25 87.5 0.0 1.1e-24 87.2 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 EAQ90398.1 - 0.14 11.8 0.0 0.37 10.4 0.0 1.7 2 1 0 2 2 2 0 alpha/beta hydrolase fold GST_N_2 PF13409.6 EAQ90399.1 - 0.0026 18.0 0.0 0.0034 17.7 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EAQ90399.1 - 0.0064 16.9 0.0 0.0094 16.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain PFL-like PF02901.15 EAQ90400.1 - 1.2e-143 480.1 0.0 1.6e-141 473.1 0.0 2.1 1 1 1 2 2 2 2 Pyruvate formate lyase-like Dyp_perox PF04261.12 EAQ90400.1 - 2.3e-26 92.6 0.0 3.7e-26 91.9 0.0 1.2 1 0 0 1 1 1 1 Dyp-type peroxidase family Pec_lyase_C PF00544.19 EAQ90402.1 - 2.1e-15 56.9 10.3 6.7e-14 52.0 10.3 2.2 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 EAQ90402.1 - 5.5e-05 23.1 1.2 5.5e-05 23.1 1.2 2.4 1 1 0 2 2 2 2 Right handed beta helix region TauD PF02668.16 EAQ90403.1 - 3.9e-17 62.9 0.0 4.7e-17 62.7 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Porin_2 PF02530.14 EAQ90403.1 - 0.023 14.0 0.1 0.033 13.5 0.1 1.1 1 0 0 1 1 1 0 Porin subfamily Ribosomal_S10 PF00338.22 EAQ90404.1 - 7e-26 90.3 0.3 8.3e-26 90.1 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Ribosomal_L17 PF01196.19 EAQ90404.1 - 0.093 13.6 0.4 0.11 13.3 0.4 1.2 1 0 0 1 1 1 0 Ribosomal protein L17 Nucleoporin_FG PF13634.6 EAQ90405.1 - 1.1e-05 26.2 111.4 0.005 17.6 24.7 5.5 2 1 5 7 7 7 6 Nucleoporin FG repeat region zf-CCCH PF00642.24 EAQ90405.1 - 4.7e-05 23.2 3.0 9.6e-05 22.2 3.0 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EAQ90405.1 - 5e-05 23.2 7.5 0.00012 22.0 7.5 1.7 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 EAQ90405.1 - 7.7e-05 22.4 3.2 0.00017 21.3 3.2 1.6 1 0 0 1 1 1 1 CCCH-type zinc finger Torus PF16131.5 EAQ90405.1 - 0.091 13.5 0.9 0.22 12.3 0.9 1.7 1 0 0 1 1 1 0 Torus domain p450 PF00067.22 EAQ90406.1 - 2.4e-49 168.3 0.0 3.2e-49 167.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.25 EAQ90408.1 - 2.8e-12 46.6 0.0 2.5e-07 30.3 0.0 2.8 2 2 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ90408.1 - 0.0015 17.8 0.0 0.0053 16.1 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 EAQ90408.1 - 0.2 11.3 0.0 0.32 10.6 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Cellulase PF00150.18 EAQ90409.1 - 5.4e-17 62.1 0.1 1.8e-16 60.4 0.1 1.7 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) ADP_PFK_GK PF04587.15 EAQ90409.1 - 0.06 11.9 0.0 0.078 11.5 0.0 1.1 1 0 0 1 1 1 0 ADP-specific Phosphofructokinase/Glucokinase conserved region Glyco_hydro_72 PF03198.14 EAQ90410.1 - 2.1e-50 171.8 0.0 2.8e-50 171.4 0.0 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 EAQ90410.1 - 0.12 11.7 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) VSP PF03302.13 EAQ90410.1 - 0.34 9.7 2.9 0.55 9.0 2.9 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein Frag1 PF10277.9 EAQ90412.1 - 5.5e-39 134.0 9.3 5.5e-39 134.0 9.3 2.6 2 0 0 2 2 2 1 Frag1/DRAM/Sfk1 family Exo_endo_phos PF03372.23 EAQ90412.1 - 0.073 12.6 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family OST3_OST6 PF04756.13 EAQ90412.1 - 0.31 10.4 1.5 0.72 9.1 1.5 1.5 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family FtsK_4TM PF13491.6 EAQ90412.1 - 6.7 6.4 44.5 0.58 9.8 11.6 4.9 4 1 1 5 5 5 0 4TM region of DNA translocase FtsK/SpoIIIE U3_assoc_6 PF08640.11 EAQ90413.1 - 2.3e-20 72.4 0.1 5.4e-20 71.2 0.1 1.6 1 0 0 1 1 1 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.6 EAQ90413.1 - 3.8e-05 24.2 2.2 0.088 13.7 0.1 3.4 1 1 2 3 3 3 2 Tetratricopeptide repeat TAtT PF16811.5 EAQ90413.1 - 0.02 14.2 0.0 0.47 9.7 0.0 2.2 2 0 0 2 2 2 0 TRAP transporter T-component NRDE-2 PF08424.10 EAQ90413.1 - 0.036 13.2 0.0 0.49 9.5 0.0 2.2 1 1 0 1 1 1 0 NRDE-2, necessary for RNA interference TPR_9 PF13371.6 EAQ90413.1 - 0.14 12.3 4.7 1.3 9.2 3.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat EVE PF01878.18 EAQ90414.1 - 4.3e-45 153.3 0.0 5.4e-45 153.0 0.0 1.0 1 0 0 1 1 1 1 EVE domain ARID PF01388.21 EAQ90416.1 - 3.2e-07 30.9 0.0 1.3e-06 29.0 0.0 2.0 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain Cmc1 PF08583.10 EAQ90416.1 - 0.055 13.5 0.1 0.4 10.7 0.0 2.1 2 0 0 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like eIF3_N PF09440.10 EAQ90417.1 - 6e-47 159.4 4.3 4.4e-46 156.6 4.3 2.2 2 0 0 2 2 2 1 eIF3 subunit 6 N terminal domain PCI PF01399.27 EAQ90417.1 - 9.1e-16 58.3 0.6 2.3e-15 57.0 0.1 2.0 2 0 0 2 2 2 1 PCI domain CSN8_PSD8_EIF3K PF10075.9 EAQ90417.1 - 0.035 14.1 0.0 0.09 12.8 0.0 1.7 1 0 0 1 1 1 0 CSN8/PSMD8/EIF3K family PC_rep PF01851.22 EAQ90419.1 - 1.5e-05 25.2 0.4 0.095 13.2 0.0 4.5 3 0 0 3 3 3 1 Proteasome/cyclosome repeat ANAPC1 PF12859.7 EAQ90419.1 - 0.0032 18.0 0.0 0.0076 16.8 0.0 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 1 Clathrin PF00637.20 EAQ90420.1 - 7.9e-21 74.4 0.4 5.9e-20 71.6 0.1 2.3 2 0 0 2 2 2 1 Region in Clathrin and VPS CENP-B_dimeris PF09026.10 EAQ90420.1 - 0.00028 21.2 6.8 0.00069 20.0 6.8 1.6 1 0 0 1 1 1 1 Centromere protein B dimerisation domain Vps39_1 PF10366.9 EAQ90420.1 - 0.0043 17.3 0.3 0.022 15.1 0.1 2.1 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 SDA1 PF05285.12 EAQ90420.1 - 0.034 13.6 2.0 0.057 12.8 2.0 1.3 1 0 0 1 1 1 0 SDA1 NOA36 PF06524.12 EAQ90420.1 - 0.085 12.2 15.3 1.1 8.5 14.0 2.1 2 0 0 2 2 2 0 NOA36 protein RXT2_N PF08595.11 EAQ90420.1 - 0.1 12.6 2.9 0.21 11.6 2.9 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF2457 PF10446.9 EAQ90420.1 - 1.7 7.7 15.3 4.8 6.2 15.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DNA_pol_phi PF04931.13 EAQ90420.1 - 3 5.8 14.4 5 5.1 14.4 1.2 1 0 0 1 1 1 0 DNA polymerase phi GST_C PF00043.25 EAQ90421.1 - 4.8e-12 45.9 0.0 7.4e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EAQ90421.1 - 5.3e-11 42.7 0.0 1.2e-10 41.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EAQ90421.1 - 2.6e-09 36.9 0.0 4.2e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EAQ90421.1 - 3.1e-09 36.9 0.0 6.7e-09 35.8 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EAQ90421.1 - 0.0003 21.1 0.0 0.00051 20.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EAQ90421.1 - 0.0073 16.6 0.0 0.012 15.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain RVT_1 PF00078.27 EAQ90422.1 - 3.6e-36 124.8 0.0 6.8e-36 123.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) YscO PF07321.12 EAQ90422.1 - 1.6 8.7 6.7 0.99 9.3 2.6 2.5 2 0 0 2 2 2 0 Type III secretion protein YscO PRKG1_interact PF15898.5 EAQ90422.1 - 9.6 7.2 6.7 7.5 7.5 4.0 2.3 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain NDC10_II PF16787.5 EAQ90423.1 - 3.9e-65 220.0 0.0 7.2e-65 219.1 0.0 1.4 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 GCR1_C PF12550.8 EAQ90423.1 - 1.7e-17 63.5 1.8 2.7e-17 62.9 0.4 2.1 2 0 0 2 2 2 1 Transcriptional activator of glycolytic enzymes PalH PF08733.10 EAQ90427.1 - 0.061 12.3 0.4 0.097 11.7 0.4 1.3 1 0 0 1 1 1 0 PalH/RIM21 AAA_13 PF13166.6 EAQ90429.1 - 0.00033 19.5 2.5 0.00033 19.5 2.5 1.7 2 0 0 2 2 2 1 AAA domain zf-CCHC PF00098.23 EAQ90429.1 - 0.0029 17.6 0.1 0.0059 16.6 0.1 1.6 1 0 0 1 1 1 1 Zinc knuckle BRE1 PF08647.11 EAQ90429.1 - 0.004 17.2 4.5 0.01 15.9 4.5 1.7 1 0 0 1 1 1 1 BRE1 E3 ubiquitin ligase HAP1_N PF04849.13 EAQ90429.1 - 0.0062 15.8 7.7 0.011 15.0 7.7 1.3 1 0 0 1 1 1 1 HAP1 N-terminal conserved region Taxilin PF09728.9 EAQ90429.1 - 0.0077 15.4 1.7 0.19 10.9 1.7 2.5 1 1 0 1 1 1 1 Myosin-like coiled-coil protein ATG16 PF08614.11 EAQ90429.1 - 0.009 16.3 10.2 0.023 14.9 10.2 1.7 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Retrotrans_gag PF03732.17 EAQ90429.1 - 0.017 15.4 1.1 0.087 13.1 0.1 2.7 2 0 0 2 2 2 0 Retrotransposon gag protein FAM76 PF16046.5 EAQ90429.1 - 0.036 13.4 2.7 0.079 12.3 2.7 1.5 1 0 0 1 1 1 0 FAM76 protein zf-CCHC_2 PF13696.6 EAQ90429.1 - 0.051 13.4 0.4 0.086 12.7 0.4 1.4 1 0 0 1 1 1 0 Zinc knuckle Spc7 PF08317.11 EAQ90429.1 - 0.053 12.4 5.9 0.11 11.4 5.9 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein SlyX PF04102.12 EAQ90429.1 - 0.11 13.1 6.3 0.23 12.1 0.7 2.9 1 1 1 2 2 2 0 SlyX DivIC PF04977.15 EAQ90429.1 - 0.17 11.6 2.7 0.52 10.1 0.2 2.7 1 1 1 2 2 2 0 Septum formation initiator DUF4407 PF14362.6 EAQ90429.1 - 0.19 11.0 5.5 0.58 9.5 5.5 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF5082 PF16888.5 EAQ90429.1 - 0.32 11.3 5.8 0.12 12.6 1.2 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF5082) UPF0242 PF06785.11 EAQ90429.1 - 0.32 11.1 5.8 0.5 10.5 4.0 1.9 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Fez1 PF06818.15 EAQ90429.1 - 0.37 11.2 4.9 0.79 10.1 4.9 1.5 1 0 0 1 1 1 0 Fez1 TMF_DNA_bd PF12329.8 EAQ90429.1 - 0.53 10.3 11.8 1.7 8.7 1.1 3.3 3 1 1 4 4 4 0 TATA element modulatory factor 1 DNA binding HIP1_clath_bdg PF16515.5 EAQ90429.1 - 0.64 10.7 5.4 2.8 8.6 5.4 2.1 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 ABC_tran_CTD PF16326.5 EAQ90429.1 - 0.65 10.3 8.8 9.4 6.6 6.3 3.1 2 1 1 3 3 3 0 ABC transporter C-terminal domain DUF724 PF05266.14 EAQ90429.1 - 0.75 9.6 3.2 1.4 8.7 3.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF4200 PF13863.6 EAQ90429.1 - 0.86 10.0 6.1 5.3 7.5 6.1 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) DUF3552 PF12072.8 EAQ90429.1 - 0.88 9.0 7.9 1.8 7.9 7.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DUF1664 PF07889.12 EAQ90429.1 - 1 9.4 3.3 2.1 8.4 3.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) COG5 PF10392.9 EAQ90429.1 - 1.1 9.4 4.5 2.8 8.1 4.5 1.7 1 0 0 1 1 1 0 Golgi transport complex subunit 5 DUF4201 PF13870.6 EAQ90429.1 - 1.4 8.7 8.1 0.17 11.6 3.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) RT_RNaseH PF17917.1 EAQ90430.1 - 4.5e-37 126.5 0.1 9.4e-37 125.5 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 EAQ90430.1 - 1.4e-34 118.1 0.0 3.4e-34 116.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 EAQ90430.1 - 4.9e-26 91.6 0.0 1.2e-25 90.4 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 EAQ90430.1 - 5.5e-14 52.0 0.0 1.7e-13 50.4 0.0 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 EAQ90430.1 - 7.4e-10 39.0 0.2 2.7e-09 37.2 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.24 EAQ90430.1 - 3.7e-08 33.2 2.5 9e-08 31.9 2.5 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 EAQ90430.1 - 0.014 15.6 0.0 0.045 14.0 0.0 1.8 1 0 0 1 1 1 0 H2C2 zinc finger IN_DBD_C PF00552.21 EAQ90430.1 - 0.27 10.6 2.3 0.31 10.4 0.1 2.2 2 0 0 2 2 2 0 Integrase DNA binding domain HpcH_HpaI PF03328.14 EAQ90434.1 - 2e-27 95.7 0.2 3.1e-27 95.2 0.2 1.3 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family ADH_zinc_N PF00107.26 EAQ90435.1 - 2e-11 44.0 0.0 3.3e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EAQ90435.1 - 0.00025 20.9 0.1 0.0022 17.8 0.0 2.3 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EAQ90435.1 - 0.002 19.2 0.0 0.0053 17.8 0.0 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Zn_clus PF00172.18 EAQ90436.1 - 0.00024 21.1 8.7 0.00037 20.5 8.7 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EAQ90438.1 - 0.1 11.6 0.0 0.5 9.4 0.0 1.9 1 1 0 1 1 1 0 Fungal specific transcription factor domain ketoacyl-synt PF00109.26 EAQ90439.1 - 2.2e-71 240.4 0.1 3.6e-71 239.7 0.1 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 EAQ90439.1 - 1.2e-46 159.8 0.0 1.8e-46 159.1 0.0 1.2 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 EAQ90439.1 - 1.6e-41 142.5 0.3 2.4e-41 141.9 0.3 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 EAQ90439.1 - 3.5e-33 114.1 0.0 7.7e-33 113.0 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 EAQ90439.1 - 4.7e-16 59.2 0.0 1.1e-15 58.0 0.0 1.6 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 EAQ90439.1 - 5.3e-05 22.7 0.1 9.9e-05 21.8 0.1 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain SAT PF16073.5 EAQ90439.1 - 0.0011 18.8 0.1 0.0081 15.9 0.1 2.1 1 1 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Condensation PF00668.20 EAQ90441.1 - 5.3e-29 101.2 0.0 7.8e-29 100.6 0.0 1.1 1 0 0 1 1 1 1 Condensation domain PP-binding PF00550.25 EAQ90441.1 - 5.2e-07 29.9 0.0 1.1e-06 28.8 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site DUF3583 PF12126.8 EAQ90441.1 - 0.26 10.7 3.7 0.41 10.1 3.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3583) AMP-binding PF00501.28 EAQ90442.1 - 1.7e-32 112.5 0.0 2.1e-32 112.3 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 EAQ90443.1 - 2.8e-13 49.6 0.0 4.8e-12 45.6 0.0 2.3 1 1 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 EAQ90443.1 - 1.7e-10 40.1 0.0 2.7e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 EAQ90443.1 - 1.1e-09 38.1 0.0 3.6e-09 36.4 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 EAQ90443.1 - 2.8e-07 30.8 0.0 8.7e-07 29.2 0.0 1.9 2 0 0 2 2 2 1 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EAQ90443.1 - 5.5e-05 24.1 0.0 0.00019 22.4 0.0 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DapB_N PF01113.20 EAQ90443.1 - 0.014 15.5 0.3 0.068 13.3 0.0 2.1 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Polysacc_synt_2 PF02719.15 EAQ90443.1 - 0.015 14.4 0.0 0.025 13.7 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein KR PF08659.10 EAQ90443.1 - 0.045 13.7 0.0 0.13 12.1 0.0 1.8 1 0 0 1 1 1 0 KR domain NAD_binding_10 PF13460.6 EAQ90443.1 - 0.049 13.5 0.1 0.22 11.4 0.1 2.1 1 1 0 1 1 1 0 NAD(P)H-binding BTB PF00651.31 EAQ90444.1 - 3.6e-12 46.5 0.0 8.9e-12 45.2 0.0 1.6 2 0 0 2 2 2 1 BTB/POZ domain FTA2 PF13095.6 EAQ90445.1 - 5.8e-06 26.1 0.0 8.1e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Prp19 PF08606.11 EAQ90445.1 - 0.11 12.5 0.2 0.18 11.8 0.2 1.2 1 0 0 1 1 1 0 Prp19/Pso4-like FCD PF07729.12 EAQ90445.1 - 0.18 12.3 0.0 0.23 11.9 0.0 1.1 1 0 0 1 1 1 0 FCD domain Bacillus_HBL PF05791.11 EAQ90445.1 - 0.19 11.6 0.0 1.5 8.6 0.0 1.8 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) SSP160 PF06933.11 EAQ90446.1 - 1.5 6.9 9.1 2.3 6.3 9.1 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Exo_endo_phos_2 PF14529.6 EAQ90447.1 - 1.4e-23 83.0 0.0 3.5e-23 81.7 0.0 1.8 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RVT_1 PF00078.27 EAQ90447.1 - 6e-18 65.2 0.0 4.1e-15 55.9 0.0 2.3 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 EAQ90447.1 - 5e-05 22.9 0.0 0.00011 21.8 0.0 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RVT_3 PF13456.6 EAQ90447.1 - 0.0011 18.8 0.0 0.0028 17.4 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase-like GCSF PF16647.5 EAQ90447.1 - 0.079 12.8 0.1 0.21 11.4 0.1 1.7 1 0 0 1 1 1 0 Granulocyte colony-stimulating factor HET PF06985.11 EAQ90448.1 - 1.7e-25 90.1 0.0 3.6e-25 89.0 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) NACHT PF05729.12 EAQ90450.1 - 6e-08 32.8 0.1 2e-07 31.0 0.1 1.9 1 0 0 1 1 1 1 NACHT domain SesA PF17107.5 EAQ90450.1 - 9.7e-07 29.0 2.1 1.2e-06 28.7 0.5 2.0 2 0 0 2 2 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases Zn_clus PF00172.18 EAQ90450.1 - 1.8e-06 27.9 11.9 3e-06 27.2 11.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AAA_22 PF13401.6 EAQ90450.1 - 2.6e-05 24.5 0.1 0.00011 22.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EAQ90450.1 - 3.3e-05 24.4 0.2 0.00024 21.5 0.1 2.4 2 0 0 2 2 2 1 AAA ATPase domain Viral_helicase1 PF01443.18 EAQ90450.1 - 0.0097 15.7 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_29 PF13555.6 EAQ90450.1 - 0.028 14.2 0.3 0.064 13.0 0.3 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 EAQ90450.1 - 0.033 14.7 0.1 0.23 12.0 0.0 2.4 2 1 1 3 3 3 0 ABC transporter Rad17 PF03215.15 EAQ90450.1 - 0.048 13.6 0.0 0.49 10.3 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_18 PF13238.6 EAQ90450.1 - 0.072 13.6 0.5 0.26 11.8 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EAQ90450.1 - 0.078 12.7 0.3 0.21 11.3 0.3 1.7 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 EAQ90450.1 - 0.28 11.6 7.8 0.6 10.6 0.2 2.6 2 0 0 2 2 2 0 AAA domain SOGA PF11365.8 EAQ90450.1 - 3.1 9.0 8.4 0.14 13.3 1.0 2.3 2 0 0 2 2 2 0 Protein SOGA Abhydrolase_6 PF12697.7 EAQ90451.1 - 1.7e-08 35.3 0.7 1.5e-07 32.2 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF1100 PF06500.11 EAQ90451.1 - 2.4e-07 29.9 0.0 3.5e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Peptidase_S9 PF00326.21 EAQ90451.1 - 1.7e-06 27.6 0.0 5.8e-06 25.9 0.0 1.9 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 EAQ90451.1 - 4.3e-05 23.3 0.2 0.00039 20.2 0.0 2.5 2 1 1 3 3 3 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EAQ90451.1 - 0.00012 21.4 0.0 0.00034 20.0 0.0 1.7 2 1 0 2 2 2 1 Serine aminopeptidase, S33 AXE1 PF05448.12 EAQ90451.1 - 0.0029 16.3 0.0 0.0073 15.0 0.0 1.6 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) DUF2920 PF11144.8 EAQ90451.1 - 0.009 15.2 0.0 0.014 14.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2920) BAAT_C PF08840.11 EAQ90451.1 - 0.04 13.8 0.0 0.077 12.9 0.0 1.4 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal UPF0227 PF05728.12 EAQ90451.1 - 0.075 13.0 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Abhydrolase_3 PF07859.13 EAQ90451.1 - 0.1 12.5 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold MKT1_C PF12246.8 EAQ90452.1 - 0.14 11.4 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 Temperature dependent protein affecting M2 dsRNA replication GCFC PF07842.12 EAQ90453.1 - 2.4e-84 283.2 2.5 2.4e-84 283.2 2.5 1.7 2 0 0 2 2 2 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.23 EAQ90453.1 - 2.3e-14 53.0 1.3 5.5e-14 51.8 1.3 1.7 1 0 0 1 1 1 1 G-patch domain TIP_N PF12457.8 EAQ90453.1 - 1.7e-13 50.8 11.6 1.7e-13 50.8 11.6 2.7 2 0 0 2 2 2 1 Tuftelin interacting protein N terminal G-patch_2 PF12656.7 EAQ90453.1 - 8e-08 32.3 5.1 1.2e-07 31.7 1.7 2.9 3 1 1 4 4 4 1 G-patch domain FUSC PF04632.12 EAQ90453.1 - 3.9 5.9 7.6 0.071 11.6 0.6 1.6 2 0 0 2 2 2 0 Fusaric acid resistance protein family Glyco_hydro_71 PF03659.14 EAQ90454.1 - 6e-41 140.5 0.5 7.1e-41 140.3 0.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Glyco_hydro_99 PF16317.5 EAQ90454.1 - 0.14 11.3 0.0 0.24 10.5 0.0 1.3 1 1 0 1 1 1 0 Glycosyl hydrolase family 99 EF-hand_7 PF13499.6 EAQ90455.1 - 1.8e-15 57.1 1.6 8.6e-08 32.5 0.3 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 EAQ90455.1 - 1.8e-14 53.3 4.1 1.7e-06 27.8 0.1 3.2 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 EAQ90455.1 - 3.9e-14 51.1 5.4 1e-08 34.1 0.0 4.2 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.6 EAQ90455.1 - 3.2e-13 48.4 2.1 8e-09 34.7 0.1 3.7 4 0 0 4 4 4 2 EF-hand domain EF-hand_5 PF13202.6 EAQ90455.1 - 4.2e-12 45.0 1.7 6.5e-07 28.6 0.1 3.6 3 0 0 3 3 3 2 EF hand EF-hand_9 PF14658.6 EAQ90455.1 - 4e-05 23.9 0.1 0.13 12.6 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain VbhA PF18495.1 EAQ90455.1 - 0.15 12.0 0.4 12 5.9 0.1 2.9 3 0 0 3 3 3 0 Antitoxin VbhA LEM PF03020.15 EAQ90455.1 - 0.48 10.0 2.3 12 5.5 0.1 3.2 2 2 1 3 3 3 0 LEM domain Amidoligase_2 PF12224.8 EAQ90457.1 - 1e-14 54.8 0.0 1.6e-14 54.2 0.0 1.3 1 0 0 1 1 1 1 Putative amidoligase enzyme HTH_21 PF13276.6 EAQ90457.1 - 0.031 14.4 5.2 0.93 9.7 2.9 2.9 2 1 0 2 2 2 0 HTH-like domain DUF3314 PF11771.8 EAQ90458.1 - 0.16 12.1 0.1 0.25 11.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3314) EHN PF06441.12 EAQ90459.1 - 2.3e-25 89.1 1.1 4.7e-25 88.1 1.1 1.5 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 EAQ90459.1 - 8.2e-07 28.9 0.0 1.6e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold GntR PF00392.21 EAQ90461.1 - 0.029 14.0 0.1 8.2 6.2 0.0 2.4 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family BTB PF00651.31 EAQ90462.1 - 0.00053 20.2 0.0 0.0019 18.4 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain PELOTA_1 PF15608.6 EAQ90462.1 - 0.087 12.7 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 PELOTA RNA binding domain RVT_1 PF00078.27 EAQ90463.1 - 6.2e-46 156.7 0.0 1.1e-45 155.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MULE PF10551.9 EAQ90463.1 - 6.8e-24 84.1 0.0 2.1e-23 82.5 0.0 1.9 2 0 0 2 2 2 1 MULE transposase domain HGTP_anticodon PF03129.20 EAQ90463.1 - 4.3e-18 65.2 0.0 1.4e-17 63.6 0.0 2.0 1 0 0 1 1 1 1 Anticodon binding domain Exo_endo_phos_2 PF14529.6 EAQ90463.1 - 4e-12 46.0 0.0 1.1e-11 44.6 0.0 1.8 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 EAQ90463.1 - 7.4e-05 22.4 0.0 0.00019 21.0 0.0 1.7 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Transposase_mut PF00872.18 EAQ90463.1 - 0.002 17.1 0.0 0.0037 16.2 0.0 1.3 1 0 0 1 1 1 1 Transposase, Mutator family Lyase_aromatic PF00221.19 EAQ90464.1 - 1.3e-138 462.5 9.3 2.4e-137 458.4 9.3 2.2 1 1 0 1 1 1 1 Aromatic amino acid lyase GT87 PF09594.10 EAQ90464.1 - 0.22 11.2 3.8 0.4 10.3 3.8 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 87 adh_short_C2 PF13561.6 EAQ90465.1 - 9.6e-54 182.4 0.4 1.4e-53 181.9 0.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EAQ90465.1 - 1.8e-47 161.3 1.7 2.2e-47 161.0 1.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EAQ90465.1 - 3.1e-12 46.8 0.3 4e-12 46.4 0.3 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EAQ90465.1 - 0.045 12.9 0.3 0.056 12.6 0.3 1.3 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein DUF1372 PF07116.11 EAQ90465.1 - 0.083 13.1 0.1 0.21 11.8 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1372) THF_DHG_CYH_C PF02882.19 EAQ90465.1 - 0.098 12.0 0.0 0.2 11.0 0.0 1.5 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Mitofilin PF09731.9 EAQ90466.1 - 1.3 7.7 8.7 1.6 7.5 8.7 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF4672 PF15716.5 EAQ90466.1 - 6.5 6.3 9.0 12 5.4 9.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4672) SAPS PF04499.15 EAQ90466.1 - 8.4 5.1 5.9 10 4.7 5.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Lipase_GDSL_2 PF13472.6 EAQ90467.1 - 1.8e-11 44.8 0.5 3.4e-10 40.6 0.5 2.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family fn3 PF00041.21 EAQ90467.1 - 1.3e-05 25.4 0.1 9.2e-05 22.7 0.0 2.1 2 0 0 2 2 2 1 Fibronectin type III domain Lipase_GDSL PF00657.22 EAQ90467.1 - 0.00012 22.1 0.0 0.00024 21.1 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 EAQ90467.1 - 0.0074 16.4 0.0 0.011 15.9 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family DUF4992 PF16383.5 EAQ90467.1 - 0.11 12.1 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function Bac_luciferase PF00296.20 EAQ90468.1 - 2.1e-67 227.8 2.9 2.7e-67 227.4 2.9 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase DUF1024 PF06260.12 EAQ90468.1 - 0.057 13.7 0.3 0.17 12.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1024) Acyl-CoA_dh_2 PF08028.11 EAQ90469.1 - 1.3e-13 51.4 1.6 2.6e-13 50.4 1.6 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EAQ90469.1 - 1.3e-05 25.8 0.0 2.4e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EAQ90469.1 - 0.0023 18.1 0.0 0.0054 16.9 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 EAQ90469.1 - 0.0077 16.4 2.6 0.025 14.8 0.2 2.3 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain SAPS PF04499.15 EAQ90470.1 - 5.2e-203 675.3 0.0 5.5e-202 671.9 0.0 2.2 2 0 0 2 2 2 1 SIT4 phosphatase-associated protein XAP5 PF04921.14 EAQ90470.1 - 8.5 6.1 6.6 2 8.2 2.3 2.1 2 0 0 2 2 2 0 XAP5, circadian clock regulator 3HCDH_N PF02737.18 EAQ90472.1 - 1.1e-51 175.3 0.6 1.5e-51 174.8 0.6 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 EAQ90472.1 - 3.8e-33 114.0 0.0 7.5e-33 113.0 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Sacchrp_dh_NADP PF03435.18 EAQ90472.1 - 4.1e-05 23.9 0.1 8.9e-05 22.8 0.1 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_2 PF03446.15 EAQ90472.1 - 0.0011 19.2 0.1 0.003 17.7 0.1 1.8 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.16 EAQ90472.1 - 0.0061 16.2 0.2 0.022 14.4 0.1 1.9 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA DAO PF01266.24 EAQ90472.1 - 0.011 15.3 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase DUF3811 PF11656.8 EAQ90472.1 - 0.016 15.6 0.1 0.028 14.8 0.1 1.3 1 0 0 1 1 1 0 YjbD family (DUF3811) Pyr_redox_2 PF07992.14 EAQ90472.1 - 0.021 14.0 0.1 0.026 13.8 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 EAQ90472.1 - 0.043 13.2 0.3 0.15 11.4 0.1 1.8 1 1 1 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 EAQ90472.1 - 0.045 13.3 0.0 0.071 12.7 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain F420_oxidored PF03807.17 EAQ90472.1 - 0.15 12.6 2.0 0.66 10.6 1.9 2.2 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Abhydrolase_3 PF07859.13 EAQ90473.1 - 1.1e-26 94.0 0.0 1.6e-26 93.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 EAQ90473.1 - 2.7e-05 23.3 0.0 3.9e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family MFS_1 PF07690.16 EAQ90474.1 - 3.7e-33 114.9 39.0 5.5e-33 114.3 39.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily SET PF00856.28 EAQ90475.1 - 0.0018 18.7 0.0 0.0049 17.3 0.0 1.7 2 0 0 2 2 2 1 SET domain K_channel_TID PF07941.11 EAQ90475.1 - 0.91 10.0 9.0 10 6.6 0.0 2.4 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain PIF1 PF05970.14 EAQ90476.1 - 1.9e-08 33.9 0.0 3.8e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 PIF1-like helicase Ank_2 PF12796.7 EAQ90477.1 - 2e-45 153.2 8.5 6.2e-15 55.5 0.2 4.2 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAQ90477.1 - 2.8e-27 94.7 0.2 8.4e-06 26.2 0.0 6.3 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 EAQ90477.1 - 3.8e-22 77.7 10.9 0.0039 17.6 0.1 7.2 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 EAQ90477.1 - 8.8e-18 64.1 0.4 0.0022 18.2 0.1 6.0 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAQ90477.1 - 1.3e-14 52.8 0.8 1.4 9.7 0.0 6.9 6 0 0 6 6 6 4 Ankyrin repeat PNP_UDP_1 PF01048.20 EAQ90477.1 - 1e-05 24.9 0.2 4e-05 23.0 0.1 2.0 2 1 0 2 2 2 1 Phosphorylase superfamily DERM PF14704.6 EAQ90477.1 - 0.54 10.7 3.9 0.41 11.1 0.2 2.5 3 0 0 3 3 3 0 Dermatopontin Arg_repressor PF01316.21 EAQ90477.1 - 0.75 9.6 4.5 1.8e+02 1.9 0.1 4.5 5 0 0 5 5 5 0 Arginine repressor, DNA binding domain DUF4766 PF15973.5 EAQ90477.1 - 0.8 10.3 11.7 4.4e+02 1.4 11.5 3.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4766) HicA_toxin PF07927.12 EAQ90477.1 - 3.4 7.8 5.6 1.6e+02 2.4 0.1 5.0 6 0 0 6 6 6 0 HicA toxin of bacterial toxin-antitoxin, SH3BGR PF04908.15 EAQ90479.1 - 0.12 12.5 0.4 0.59 10.3 0.0 2.2 1 1 1 2 2 2 0 SH3-binding, glutamic acid-rich protein Polysacc_deac_1 PF01522.21 EAQ90481.1 - 2e-16 60.0 0.2 4.9e-16 58.8 0.1 1.7 1 1 1 2 2 2 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 EAQ90481.1 - 0.016 14.4 0.0 0.023 13.9 0.0 1.2 1 1 0 1 1 1 0 Glycosyl hydrolase family 57 Fungal_trans PF04082.18 EAQ90482.1 - 3.5e-25 88.5 0.0 8.9e-25 87.2 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EAQ90482.1 - 7.5e-10 38.8 12.6 1.4e-09 37.9 12.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_M41 PF01434.18 EAQ90483.1 - 7.5e-67 224.9 0.0 1.3e-66 224.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 EAQ90483.1 - 2.1e-42 144.6 0.0 4.5e-42 143.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EAQ90483.1 - 6.1e-11 41.9 0.3 1.4e-10 40.8 0.3 1.6 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 EAQ90483.1 - 1.5e-10 41.4 0.0 4e-10 40.0 0.0 1.8 1 0 0 1 1 1 1 FtsH Extracellular AAA_16 PF13191.6 EAQ90483.1 - 0.0016 18.8 0.4 0.13 12.7 0.2 3.1 2 1 0 3 3 3 1 AAA ATPase domain AAA_17 PF13207.6 EAQ90483.1 - 0.0016 18.8 0.1 1.4 9.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.12 EAQ90483.1 - 0.0044 16.8 0.0 0.019 14.7 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 EAQ90483.1 - 0.0068 16.4 0.1 0.037 14.0 0.0 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 EAQ90483.1 - 0.013 14.7 0.0 0.025 13.8 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_22 PF13401.6 EAQ90483.1 - 0.014 15.7 0.0 0.67 10.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 EAQ90483.1 - 0.032 14.0 0.0 0.084 12.6 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_2 PF07724.14 EAQ90483.1 - 0.038 14.1 0.8 0.1 12.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) Pex14_N PF04695.13 EAQ90483.1 - 0.74 10.5 8.4 1.5 9.5 8.4 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CDC45 PF02724.14 EAQ90483.1 - 0.81 7.9 6.0 1.1 7.5 6.0 1.1 1 0 0 1 1 1 0 CDC45-like protein R3H-assoc PF13902.6 EAQ90483.1 - 1.8 9.0 9.4 3.7 7.9 9.4 1.5 1 0 0 1 1 1 0 R3H-associated N-terminal domain DUF2477 PF10631.9 EAQ90483.1 - 5.2 7.7 7.8 10 6.8 7.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2477) HCO3_cotransp PF00955.21 EAQ90484.1 - 5.4e-62 210.3 18.2 1.6e-27 96.5 0.2 3.0 2 1 1 3 3 3 3 HCO3- transporter family SelK_SelG PF10961.8 EAQ90486.1 - 0.12 13.0 0.5 0.3 11.7 0.5 1.7 1 1 0 1 1 1 0 Selenoprotein SelK_SelG Homeodomain PF00046.29 EAQ90487.1 - 1.4e-14 53.7 2.3 2.8e-14 52.7 2.3 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 EAQ90487.1 - 0.0031 17.4 0.1 0.0072 16.2 0.1 1.6 1 0 0 1 1 1 1 Homeobox KN domain TIMELESS PF04821.14 EAQ90489.1 - 2.6e-83 279.5 0.6 8.3e-83 277.8 0.1 2.1 2 0 0 2 2 2 1 Timeless protein TIMELESS_C PF05029.13 EAQ90489.1 - 4.8e-33 115.1 0.1 4.8e-33 115.1 0.1 4.2 3 1 0 4 4 4 1 Timeless protein C terminal region Cnd1_N PF12922.7 EAQ90489.1 - 0.079 12.8 0.3 15 5.4 0.1 3.0 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1, N-term CNDH2_C PF16858.5 EAQ90489.1 - 9.8 5.9 16.7 0.6 9.9 1.0 3.5 3 0 0 3 3 3 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term MFS_1 PF07690.16 EAQ90490.1 - 1.7e-43 148.9 43.4 1.7e-43 148.9 43.4 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EAQ90490.1 - 2.2e-16 59.8 9.4 2.2e-16 59.8 9.4 2.6 3 0 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 EAQ90490.1 - 6.3e-10 38.1 18.6 9.4e-10 37.5 18.6 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Ank_2 PF12796.7 EAQ90491.1 - 4.6e-57 190.6 7.6 1.1e-12 48.3 0.1 6.4 1 1 6 8 8 8 8 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAQ90491.1 - 1.5e-29 98.7 6.1 0.00018 21.7 0.1 12.6 13 0 0 13 13 12 5 Ankyrin repeat Ank_4 PF13637.6 EAQ90491.1 - 9.5e-27 93.0 8.7 7.9e-08 32.7 0.3 10.8 5 3 8 13 13 13 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAQ90491.1 - 2.6e-26 91.3 10.8 1.2e-07 31.9 0.4 8.7 4 2 5 9 9 9 5 Ankyrin repeats (many copies) Ank PF00023.30 EAQ90491.1 - 4.7e-24 83.7 15.7 3.1e-05 24.2 1.1 11.8 12 0 0 12 12 12 5 Ankyrin repeat NACHT PF05729.12 EAQ90491.1 - 2.1e-10 40.7 0.0 4.5e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EAQ90491.1 - 3.1e-05 24.4 1.3 0.00011 22.7 0.1 2.5 2 0 0 2 2 2 1 AAA ATPase domain Helo_like_N PF17111.5 EAQ90491.1 - 0.0011 18.3 0.6 0.0033 16.8 0.6 1.7 1 1 0 1 1 1 1 Fungal N-terminal domain of STAND proteins SesA PF17107.5 EAQ90491.1 - 0.0048 17.1 0.9 0.023 14.9 0.2 2.5 2 1 1 3 3 3 1 N-terminal domain on NACHT_NTPase and P-loop NTPases AAA_19 PF13245.6 EAQ90491.1 - 0.058 13.7 0.2 1.9 8.8 0.0 2.7 3 0 0 3 3 3 0 AAA domain DUF2353 PF09789.9 EAQ90491.1 - 0.093 12.1 0.1 0.17 11.2 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) NB-ARC PF00931.22 EAQ90491.1 - 0.12 11.5 0.0 0.3 10.2 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain Syntaxin_2 PF14523.6 EAQ90491.1 - 0.16 12.3 0.9 0.49 10.8 0.1 2.2 2 1 0 2 2 2 0 Syntaxin-like protein AAA_14 PF13173.6 EAQ90491.1 - 0.18 11.8 0.2 0.69 10.0 0.0 2.1 3 0 0 3 3 3 0 AAA domain YndJ PF14158.6 EAQ90491.1 - 0.28 10.5 2.1 0.58 9.4 2.1 1.4 1 0 0 1 1 1 0 YndJ-like protein GFO_IDH_MocA PF01408.22 EAQ90492.1 - 4.5e-09 37.2 0.7 2e-08 35.1 0.7 2.1 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 EAQ90492.1 - 0.12 13.0 0.0 0.22 12.2 0.0 1.5 1 1 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain DHDPS PF00701.22 EAQ90493.1 - 3e-09 36.0 0.0 4.2e-09 35.5 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family DAO PF01266.24 EAQ90494.1 - 2.3e-70 237.9 1.3 2.8e-70 237.7 1.3 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EAQ90494.1 - 2.1e-05 23.9 0.2 0.004 16.4 0.0 2.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EAQ90494.1 - 3.1e-05 24.1 0.4 7.3e-05 22.9 0.4 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EAQ90494.1 - 8e-05 23.1 0.0 0.028 15.0 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.19 EAQ90494.1 - 0.00079 18.9 0.1 0.45 9.8 0.0 2.2 2 0 0 2 2 2 2 GMC oxidoreductase Trp_halogenase PF04820.14 EAQ90494.1 - 0.0027 16.6 0.2 0.0045 15.9 0.2 1.3 1 0 0 1 1 1 1 Tryptophan halogenase Thi4 PF01946.17 EAQ90494.1 - 0.0041 16.4 0.1 0.0068 15.7 0.1 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 EAQ90494.1 - 0.0047 16.1 0.3 2 7.4 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Amino_oxidase PF01593.24 EAQ90494.1 - 0.03 13.6 0.1 0.1 11.9 0.0 1.9 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase MCRA PF06100.11 EAQ90494.1 - 0.066 12.0 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 MCRA family Mqo PF06039.15 EAQ90494.1 - 0.12 10.8 0.0 6.1 5.3 0.0 2.0 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) GSHPx PF00255.19 EAQ90495.1 - 4.9e-23 80.8 0.0 6.6e-23 80.4 0.0 1.1 1 0 0 1 1 1 1 Glutathione peroxidase DUF4174 PF13778.6 EAQ90495.1 - 0.11 13.0 0.0 0.12 12.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4174) Fungal_trans_2 PF11951.8 EAQ90497.1 - 2.9e-35 121.8 0.1 4.1e-34 118.0 0.1 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EAQ90497.1 - 1.3e-06 28.4 6.9 1.3e-06 28.4 6.9 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_S3 PF00944.19 EAQ90498.1 - 0.012 15.4 0.0 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 Alphavirus core protein Trypsin_2 PF13365.6 EAQ90498.1 - 0.13 13.2 0.3 1.8 9.5 0.3 2.4 1 1 0 1 1 1 0 Trypsin-like peptidase domain Nop16 PF09420.10 EAQ90499.1 - 5.9e-35 121.2 0.2 6.7e-35 121.0 0.2 1.0 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 PIF1 PF05970.14 EAQ90501.1 - 1.3e-16 60.8 0.0 1.5e-12 47.4 0.0 2.3 2 0 0 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 EAQ90501.1 - 4.4e-06 26.5 0.0 8.1e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 EAQ90501.1 - 0.00026 20.7 0.1 0.00079 19.2 0.1 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.14 EAQ90501.1 - 0.00038 18.6 0.1 0.00096 17.2 0.1 1.6 2 0 0 2 2 2 1 Helicase AAA_19 PF13245.6 EAQ90501.1 - 0.0066 16.8 0.0 0.013 15.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EAQ90501.1 - 0.076 13.3 0.0 0.67 10.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 EAQ90501.1 - 0.17 11.6 1.7 16 5.2 0.0 2.5 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase RVT_1 PF00078.27 EAQ90502.1 - 0.00075 19.1 0.0 0.0019 17.8 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RhoGAP PF00620.27 EAQ90503.1 - 1.4e-13 50.9 0.1 3.8e-13 49.5 0.0 1.8 2 0 0 2 2 2 1 RhoGAP domain DEP PF00610.21 EAQ90503.1 - 1.5e-13 50.6 0.0 3.2e-13 49.5 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) FCH PF00611.23 EAQ90503.1 - 1.1e-10 41.6 0.0 4e-10 39.8 0.0 2.0 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain BAR PF03114.18 EAQ90503.1 - 0.0021 17.8 1.9 0.0057 16.3 0.5 2.2 2 0 0 2 2 2 1 BAR domain DUF4325 PF14213.6 EAQ90503.1 - 0.11 12.2 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 STAS-like domain of unknown function (DUF4325) Phage_TAC_8 PF10666.9 EAQ90503.1 - 0.28 11.5 1.9 0.32 11.3 0.1 2.1 3 0 0 3 3 3 0 Phage tail assembly chaperone protein Gp14 ()A118 DUF2951 PF11166.8 EAQ90503.1 - 7.9 6.8 5.8 1.3 9.2 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2951) Ribosomal_S13 PF00416.22 EAQ90506.1 - 4.2e-13 49.8 0.5 1.9e-11 44.5 2.3 1.9 1 1 1 2 2 2 1 Ribosomal protein S13/S18 Methyltransf_32 PF13679.6 EAQ90507.1 - 7.9e-23 81.2 0.1 3.1e-22 79.2 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain ACT_7 PF13840.6 EAQ90508.1 - 1.2e-19 69.8 0.1 2.2e-19 69.0 0.1 1.4 1 0 0 1 1 1 1 ACT domain UPF0029 PF01205.19 EAQ90509.1 - 1e-32 112.6 0.0 1.6e-32 111.9 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.22 EAQ90509.1 - 1e-07 32.2 0.0 2.1e-07 31.2 0.0 1.5 1 1 0 1 1 1 1 RWD domain GGACT PF06094.12 EAQ90510.1 - 2.4e-23 83.0 0.0 3e-23 82.7 0.0 1.1 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like DUF4932 PF16286.5 EAQ90510.1 - 0.062 12.6 0.0 0.072 12.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4932) Glyco_hydro_61 PF03443.14 EAQ90512.1 - 3.2e-05 24.0 0.0 5.5e-05 23.2 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 61 LPMO_10 PF03067.15 EAQ90512.1 - 0.0055 17.4 0.0 0.0086 16.8 0.0 1.3 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading FAT PF02259.23 EAQ90513.1 - 2.4e-77 260.5 4.0 4.4e-77 259.6 4.0 1.5 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.27 EAQ90513.1 - 2.1e-30 106.4 0.0 4.5e-30 105.3 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 EAQ90513.1 - 1.9e-07 30.8 0.1 5.4e-07 29.3 0.1 1.9 1 0 0 1 1 1 1 FATC domain DUF1765 PF08578.10 EAQ90513.1 - 0.08 13.4 0.3 2.5 8.6 0.1 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1765) TPR_2 PF07719.17 EAQ90513.1 - 0.25 11.5 1.4 18 5.7 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Sec7_N PF12783.7 EAQ90513.1 - 0.7 9.8 10.6 4.1 7.3 0.1 5.1 5 0 0 5 5 5 0 Guanine nucleotide exchange factor in Golgi transport N-terminal AMP-binding PF00501.28 EAQ90514.1 - 2.4e-27 95.6 0.0 3.5e-27 95.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 EAQ90514.1 - 2.5e-05 24.1 0.0 5.3e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus ANAPC3 PF12895.7 EAQ90515.1 - 1.5e-24 86.0 23.4 7.8e-24 83.7 1.2 5.5 4 2 3 7 7 7 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 EAQ90515.1 - 2.7e-22 77.0 29.3 0.0026 17.8 0.0 10.7 11 0 0 11 11 10 6 Tetratricopeptide repeat TPR_19 PF14559.6 EAQ90515.1 - 1.2e-20 73.7 26.8 2.6e-05 24.6 0.1 8.4 5 2 3 9 9 9 7 Tetratricopeptide repeat TPR_1 PF00515.28 EAQ90515.1 - 5.2e-19 67.2 20.4 0.0004 20.1 1.3 9.9 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_14 PF13428.6 EAQ90515.1 - 7.7e-15 54.3 34.0 0.012 16.4 0.7 10.2 4 2 6 10 10 10 4 Tetratricopeptide repeat TPR_12 PF13424.6 EAQ90515.1 - 1.1e-13 51.3 32.0 6.5e-06 26.4 0.8 8.9 6 2 2 9 9 9 3 Tetratricopeptide repeat TPR_16 PF13432.6 EAQ90515.1 - 8.9e-13 48.7 36.2 0.00017 22.1 0.3 9.0 7 2 2 9 9 9 4 Tetratricopeptide repeat TPR_8 PF13181.6 EAQ90515.1 - 3.5e-12 45.5 10.3 0.0034 17.5 0.4 8.7 10 0 0 10 10 9 1 Tetratricopeptide repeat TPR_10 PF13374.6 EAQ90515.1 - 4.2e-08 32.8 14.7 0.023 14.5 0.1 7.3 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_6 PF13174.6 EAQ90515.1 - 0.00025 21.5 16.8 0.55 11.0 0.5 7.6 8 0 0 8 8 6 1 Tetratricopeptide repeat TPR_11 PF13414.6 EAQ90515.1 - 0.00031 20.3 16.2 0.32 10.7 0.0 6.8 5 1 2 7 7 7 1 TPR repeat TPR_7 PF13176.6 EAQ90515.1 - 0.0012 18.7 23.2 9.2 6.6 0.1 8.9 10 0 0 10 10 9 1 Tetratricopeptide repeat TPR_15 PF13429.6 EAQ90515.1 - 0.0013 18.0 12.2 0.33 10.1 0.0 4.7 3 2 1 5 5 5 2 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 EAQ90515.1 - 0.014 15.0 0.0 4 7.1 0.0 2.9 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_21 PF09976.9 EAQ90515.1 - 0.026 14.2 5.2 2 8.1 0.0 4.3 5 0 0 5 5 4 0 Tetratricopeptide repeat-like domain SRP_TPR_like PF17004.5 EAQ90515.1 - 0.028 14.4 0.3 11 6.1 0.0 3.6 3 1 0 3 3 3 0 Putative TPR-like repeat TPR_MalT PF17874.1 EAQ90515.1 - 0.031 13.6 11.3 0.058 12.8 3.9 3.8 3 2 1 4 4 4 0 MalT-like TPR region TPR_5 PF12688.7 EAQ90515.1 - 0.13 12.5 0.3 0.13 12.5 0.3 2.6 3 1 0 3 3 1 0 Tetratrico peptide repeat TPR_4 PF07721.14 EAQ90515.1 - 7 7.6 24.0 3.1 8.7 0.1 7.2 8 0 0 8 8 7 0 Tetratricopeptide repeat Alk_phosphatase PF00245.20 EAQ90516.1 - 1.6e-66 225.0 0.0 2.1e-66 224.6 0.0 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Sulfatase PF00884.23 EAQ90516.1 - 4.7e-06 26.2 0.0 8.9e-06 25.3 0.0 1.5 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 EAQ90516.1 - 5.1e-06 26.3 0.8 1.4e-05 24.9 0.8 1.8 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 EAQ90516.1 - 0.0032 16.2 0.1 0.0049 15.5 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) DUF1501 PF07394.12 EAQ90516.1 - 0.035 13.2 0.1 0.053 12.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) CutC PF03932.14 EAQ90518.1 - 2.6e-12 46.7 2.7 5.7e-08 32.5 0.0 3.9 3 1 0 3 3 3 3 CutC family PGP_phosphatase PF09419.10 EAQ90520.1 - 2.5e-67 225.7 0.0 3.4e-67 225.3 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.6 EAQ90520.1 - 0.00014 21.9 0.0 0.00032 20.7 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like ORC2 PF04084.14 EAQ90521.1 - 5.6e-103 344.3 0.0 6.7e-103 344.1 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 DEAD PF00270.29 EAQ90522.1 - 5.2e-49 166.4 0.0 1.8e-48 164.7 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EAQ90522.1 - 8.9e-34 116.2 0.0 2.6e-33 114.7 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EAQ90522.1 - 0.0026 17.8 0.0 0.0042 17.1 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 EAQ90522.1 - 0.11 11.8 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit ERCC3_RAD25_C PF16203.5 EAQ90522.1 - 0.11 11.6 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase WD40 PF00400.32 EAQ90523.1 - 9.2e-21 73.8 0.7 1.6e-05 25.6 0.0 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat Peptidase_C48 PF02902.19 EAQ90524.1 - 6.3e-29 101.4 0.0 9.2e-29 100.8 0.0 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Ndufs5 PF10200.9 EAQ90526.1 - 0.00028 21.1 0.0 0.00035 20.8 0.0 1.2 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa DUF3128 PF11326.8 EAQ90526.1 - 0.0058 17.0 3.0 0.017 15.4 3.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3128) COX6B PF02297.17 EAQ90526.1 - 0.015 15.5 0.2 0.024 14.9 0.2 1.4 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb CHCH PF06747.13 EAQ90526.1 - 0.021 14.9 1.2 0.044 13.9 1.2 1.6 1 0 0 1 1 1 0 CHCH domain UPF0203 PF05254.12 EAQ90526.1 - 0.068 13.4 0.9 0.11 12.8 0.9 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0203) Pkinase PF00069.25 EAQ90527.1 - 4.1e-06 26.3 0.0 6.9e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Choline_kinase PF01633.20 EAQ90527.1 - 0.002 17.7 0.0 0.0033 17.0 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase_Tyr PF07714.17 EAQ90527.1 - 0.075 12.3 0.0 0.51 9.6 0.0 2.0 2 0 0 2 2 2 0 Protein tyrosine kinase Sec39 PF08314.11 EAQ90529.1 - 1.5e-223 744.5 0.0 5.8e-117 392.1 0.0 2.0 1 1 1 2 2 2 2 Secretory pathway protein Sec39 Rota_NS6 PF04866.12 EAQ90530.1 - 0.092 13.0 0.0 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 Rotavirus non-structural protein 6 DIOX_N PF14226.6 EAQ90531.1 - 2.6e-13 50.8 0.4 2.2e-08 34.9 0.0 2.3 2 0 0 2 2 2 2 non-haem dioxygenase in morphine synthesis N-terminal GCD14 PF08704.10 EAQ90532.1 - 3.8e-62 210.2 0.0 1.5e-46 159.1 0.0 2.4 2 0 0 2 2 2 2 tRNA methyltransferase complex GCD14 subunit MS_channel PF00924.18 EAQ90533.1 - 5.1e-22 78.4 2.8 9.2e-22 77.6 2.8 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel E1-E2_ATPase PF00122.20 EAQ90533.1 - 0.084 12.4 5.7 3.6 7.1 0.0 2.9 3 0 0 3 3 3 0 E1-E2 ATPase EF-hand_5 PF13202.6 EAQ90533.1 - 0.17 11.5 0.0 0.37 10.4 0.0 1.6 1 0 0 1 1 1 0 EF hand Glyco_hydro_31 PF01055.26 EAQ90534.1 - 1.6e-141 472.5 2.6 2.3e-141 472.0 2.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 EAQ90534.1 - 3.3e-25 88.2 0.5 1.6e-23 82.8 0.2 2.8 3 0 0 3 3 3 1 Galactose mutarotase-like DUF5110 PF17137.4 EAQ90534.1 - 6.2e-05 23.2 0.0 0.00029 21.1 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF5110) NDK PF00334.19 EAQ90535.1 - 1.7e-52 177.0 0.0 1.9e-52 176.8 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase FLILHELTA PF10306.9 EAQ90536.1 - 1.3e-30 105.7 0.1 2.3e-30 104.8 0.1 1.4 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA DUF1279 PF06916.13 EAQ90536.1 - 0.081 13.5 0.1 0.15 12.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1279) DNA_ligase_A_N PF04675.14 EAQ90537.1 - 2e-18 67.3 0.0 4.2e-18 66.3 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_M PF01068.21 EAQ90537.1 - 1.5e-15 57.4 0.1 7.2e-13 48.7 0.1 2.3 1 1 0 1 1 1 1 ATP dependent DNA ligase domain RNA_ligase PF09414.10 EAQ90537.1 - 0.0012 19.2 0.0 0.0027 18.0 0.0 1.6 1 0 0 1 1 1 1 RNA ligase Transp_cyt_pur PF02133.15 EAQ90538.1 - 2.9e-22 79.0 12.6 3.5e-22 78.8 12.6 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Tmemb_40 PF10160.9 EAQ90538.1 - 0.033 13.6 1.2 0.033 13.6 1.2 1.7 2 1 0 2 2 2 0 Predicted membrane protein Glyoxalase PF00903.25 EAQ90539.1 - 2.1e-08 34.4 0.1 4.3e-08 33.4 0.1 1.5 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Peptidase_M50B PF13398.6 EAQ90540.1 - 3.7e-61 206.3 18.4 4.6e-61 206.0 18.4 1.1 1 0 0 1 1 1 1 Peptidase M50B-like Peptidase_M50 PF02163.22 EAQ90540.1 - 0.042 13.1 0.1 0.068 12.4 0.1 1.4 1 0 0 1 1 1 0 Peptidase family M50 UCR_Fe-S_N PF10399.9 EAQ90540.1 - 0.12 11.8 0.1 0.12 11.8 0.1 3.4 3 0 0 3 3 3 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal YjcB PF15940.5 EAQ90540.1 - 1.2 9.4 5.7 0.31 11.3 1.9 2.3 2 1 0 2 2 2 0 Family of unknown function YlaC PF10777.9 EAQ90540.1 - 1.6 8.5 4.1 0.47 10.3 0.4 1.8 2 0 0 2 2 2 0 Inner membrane protein YlaC CAF1A PF12253.8 EAQ90541.1 - 1.3e-21 76.6 2.3 1.3e-21 76.6 2.3 3.7 2 1 0 2 2 2 1 Chromatin assembly factor 1 subunit A Peptidase_S64 PF08192.11 EAQ90541.1 - 1.2 7.6 22.7 2.2 6.7 22.7 1.5 1 0 0 1 1 1 0 Peptidase family S64 V_ATPase_I PF01496.19 EAQ90541.1 - 4.6 5.0 16.0 6.5 4.5 16.0 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Raftlin PF15250.6 EAQ90541.1 - 6 5.5 22.8 14 4.3 22.8 1.6 1 0 0 1 1 1 0 Raftlin Glucokinase PF02685.16 EAQ90542.1 - 0.0061 15.6 0.1 0.01 14.9 0.1 1.3 1 0 0 1 1 1 1 Glucokinase SPX PF03105.19 EAQ90543.1 - 5e-84 283.4 0.3 6.8e-84 283.0 0.3 1.2 1 0 0 1 1 1 1 SPX domain EXS PF03124.14 EAQ90543.1 - 4.9e-42 144.4 21.7 3.1e-23 82.6 7.5 2.1 1 1 1 2 2 2 2 EXS family CENP-Q PF13094.6 EAQ90543.1 - 0.07 13.3 0.4 0.13 12.4 0.4 1.4 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF883 PF05957.13 EAQ90543.1 - 0.38 11.4 2.3 1.1 9.9 2.3 1.7 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Peptidase_M18 PF02127.15 EAQ90544.1 - 3.6e-128 428.0 0.0 4.1e-128 427.8 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) TMEM125 PF15109.6 EAQ90544.1 - 0.1 13.0 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 TMEM125 protein family PAF-AH_p_II PF03403.13 EAQ90545.1 - 7.3e-38 130.1 0.0 5.9e-32 110.6 0.0 2.1 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 EAQ90545.1 - 0.00019 20.4 0.0 0.00032 19.7 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 EAQ90545.1 - 0.013 14.6 0.0 0.021 13.9 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Hydrolase_4 PF12146.8 EAQ90545.1 - 0.082 12.2 1.3 0.2 10.9 0.1 2.0 2 0 0 2 2 2 0 Serine aminopeptidase, S33 LSM PF01423.22 EAQ90547.1 - 7.7e-17 60.7 0.2 1.1e-16 60.2 0.2 1.3 1 0 0 1 1 1 1 LSM domain Ribosomal_S21e PF01249.18 EAQ90547.1 - 0.04 14.0 0.0 0.057 13.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein S21e Ammonium_transp PF00909.21 EAQ90548.1 - 0.043 12.5 0.4 0.088 11.5 0.4 1.4 1 0 0 1 1 1 0 Ammonium Transporter Family UQ_con PF00179.26 EAQ90549.1 - 2.4e-50 169.8 0.0 2.8e-50 169.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EAQ90549.1 - 0.12 12.1 0.0 0.23 11.1 0.0 1.7 1 1 0 1 1 1 0 Prokaryotic E2 family B TPR_2 PF07719.17 EAQ90550.1 - 3.3e-05 23.7 1.1 1.7 8.9 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 EAQ90550.1 - 6.2e-05 22.6 0.0 0.15 11.9 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat UBA PF00627.31 EAQ90550.1 - 0.016 15.1 0.0 0.042 13.8 0.0 1.8 1 0 0 1 1 1 0 UBA/TS-N domain TPR_12 PF13424.6 EAQ90550.1 - 0.078 13.3 0.0 0.078 13.3 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF630 PF04783.12 EAQ90550.1 - 0.081 13.1 0.1 0.21 11.8 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF630) DUF1996 PF09362.10 EAQ90551.1 - 2.6e-65 220.7 0.6 3.8e-57 194.0 0.0 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF1996) DUF572 PF04502.13 EAQ90554.1 - 2.1e-46 159.1 11.9 1.6e-45 156.2 11.9 1.9 1 1 0 1 1 1 1 Family of unknown function (DUF572) Dynamitin PF04912.14 EAQ90554.1 - 0.0073 15.7 5.3 0.0099 15.2 5.3 1.2 1 0 0 1 1 1 1 Dynamitin Cas_Csy2 PF09614.10 EAQ90554.1 - 0.16 11.3 0.3 0.23 10.8 0.3 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy2) CAP_N PF01213.19 EAQ90554.1 - 3.4 7.1 7.2 0.2 11.1 1.4 1.7 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal GCP_N_terminal PF17681.1 EAQ90555.1 - 2.2e-35 122.8 0.1 6e-35 121.4 0.0 1.7 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 EAQ90555.1 - 2.4e-27 96.3 0.0 5.7e-27 95.0 0.0 1.6 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal GCP5-Mod21 PF14609.6 EAQ90555.1 - 0.21 9.9 0.0 0.29 9.4 0.0 1.2 1 0 0 1 1 1 0 gamma-Tubulin ring complex non-core subunit mod21 Glyco_transf_15 PF01793.16 EAQ90556.1 - 6.7e-95 318.1 12.7 8.3e-95 317.7 12.7 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase WD40 PF00400.32 EAQ90557.1 - 1.5e-11 44.6 8.6 0.11 13.4 0.0 6.6 6 1 1 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAQ90557.1 - 1.9e-05 24.8 0.0 0.24 11.7 0.0 4.3 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ PF01011.21 EAQ90557.1 - 0.024 14.6 5.0 1.7 8.7 0.2 4.4 4 0 0 4 4 4 0 PQQ enzyme repeat PQQ_3 PF13570.6 EAQ90557.1 - 2.9 8.5 12.3 0.89 10.1 1.5 4.7 4 1 1 5 5 5 0 PQQ-like domain Serglycin PF04360.12 EAQ90557.1 - 6.8 6.6 9.8 12 5.8 9.8 1.4 1 0 0 1 1 1 0 Serglycin Zn_clus PF00172.18 EAQ90558.1 - 4.8e-07 29.8 8.7 7.9e-07 29.1 8.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PQ-loop PF04193.14 EAQ90562.1 - 1.2e-16 60.3 3.8 7.9e-13 48.0 1.5 2.4 2 0 0 2 2 2 2 PQ loop repeat MTHFR PF02219.17 EAQ90564.1 - 1.3e-100 336.5 0.0 1.6e-100 336.2 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase IF4E PF01652.18 EAQ90565.1 - 5.3e-55 185.6 0.0 7.9e-55 185.0 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E UCH PF00443.29 EAQ90566.1 - 4.9e-25 88.5 0.0 7.3e-25 87.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 EAQ90566.1 - 2.4e-12 47.0 0.2 4.4e-12 46.1 0.2 1.4 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 EAQ90566.1 - 0.0051 16.4 0.5 0.52 9.9 0.2 2.5 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Utp13 PF08625.11 EAQ90567.1 - 3.3e-51 172.9 0.1 5.5e-51 172.2 0.1 1.4 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain WD40 PF00400.32 EAQ90567.1 - 2.1e-43 145.4 17.8 7.6e-07 29.7 0.0 11.8 11 0 0 11 11 11 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAQ90567.1 - 8.2e-14 51.7 7.4 0.066 13.5 0.0 9.2 5 2 5 10 10 10 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EAQ90567.1 - 0.00075 18.3 5.1 0.7 8.5 0.0 4.9 5 1 0 5 5 5 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 EAQ90567.1 - 0.0018 17.1 5.4 3 6.5 0.0 5.4 5 2 1 6 6 6 2 Nup133 N terminal like MSA-2c PF12238.8 EAQ90568.1 - 0.61 10.1 4.5 1.1 9.3 4.5 1.4 1 0 0 1 1 1 0 Merozoite surface antigen 2c CENP-S PF15630.6 EAQ90569.1 - 4.7e-35 119.8 0.1 8e-35 119.1 0.0 1.4 1 1 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 EAQ90569.1 - 1.5e-08 34.7 0.1 1.7e-08 34.5 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Bromo_TP PF07524.13 EAQ90569.1 - 0.0013 18.7 0.0 0.002 18.1 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated TFIID-18kDa PF02269.16 EAQ90569.1 - 0.003 17.6 0.0 0.004 17.2 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit DUF2972 PF11186.8 EAQ90569.1 - 0.049 13.6 0.0 0.052 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2972) TFIID-31kDa PF02291.15 EAQ90569.1 - 0.072 13.2 0.1 0.084 13.0 0.1 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit PGA2 PF07543.12 EAQ90570.1 - 1.5e-26 93.0 8.9 2.2e-26 92.5 8.9 1.2 1 0 0 1 1 1 1 Protein trafficking PGA2 SLY PF12485.8 EAQ90570.1 - 0.28 11.9 1.8 0.58 10.9 1.8 1.5 1 1 0 1 1 1 0 Lymphocyte signaling adaptor protein PPTA PF01239.22 EAQ90571.1 - 5.9e-36 121.2 10.5 1.5e-06 27.7 0.1 5.5 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat TPR_19 PF14559.6 EAQ90571.1 - 0.0037 17.7 1.8 3.5 8.2 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 EAQ90571.1 - 0.05 13.8 2.5 1 9.7 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 EAQ90571.1 - 0.27 11.4 1.0 4.5 7.5 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Ndc1_Nup PF09531.10 EAQ90571.1 - 1.1 7.8 3.2 1.4 7.5 3.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TPR_2 PF07719.17 EAQ90571.1 - 5.2 7.4 5.5 5.9 7.3 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat GHMP_kinases_N PF00288.26 EAQ90572.1 - 9.2e-15 54.6 0.0 1.9e-14 53.6 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EAQ90572.1 - 1.1e-09 38.6 0.0 2.5e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.9 EAQ90572.1 - 0.003 17.1 0.0 0.0056 16.2 0.0 1.4 1 0 0 1 1 1 1 Galactokinase galactose-binding signature Collagen PF01391.18 EAQ90572.1 - 1.4 8.8 11.0 0.029 14.1 2.7 2.1 2 0 0 2 2 2 0 Collagen triple helix repeat (20 copies) ABM PF03992.16 EAQ90573.1 - 0.31 11.2 4.4 0.5 10.5 4.4 1.5 1 1 0 1 1 1 0 Antibiotic biosynthesis monooxygenase Ribosomal_L38e PF01781.18 EAQ90574.1 - 9.2e-34 115.4 2.1 1.1e-33 115.1 2.1 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family Ish1 PF10281.9 EAQ90575.1 - 0.065 13.6 0.1 0.076 13.3 0.1 1.2 1 0 0 1 1 1 0 Putative stress-responsive nuclear envelope protein Peptidase_M48_N PF16491.5 EAQ90576.1 - 1.1e-49 168.8 1.4 1.7e-49 168.2 1.4 1.3 1 0 0 1 1 1 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 EAQ90576.1 - 2e-12 47.3 0.0 5.8e-12 45.8 0.0 1.7 2 0 0 2 2 2 1 Peptidase family M48 Glyco_hydro_3_C PF01915.22 EAQ90578.1 - 1.3e-31 110.2 0.0 1.8e-31 109.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EAQ90578.1 - 5e-31 108.2 0.0 8.5e-31 107.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EAQ90578.1 - 3.7e-23 81.4 0.6 7.8e-23 80.4 0.6 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain Lipase_3 PF01764.25 EAQ90579.1 - 1.1e-36 125.8 0.0 1.5e-36 125.4 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 EAQ90579.1 - 6.7e-06 26.9 0.5 9.6e-06 26.3 0.5 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EAQ90579.1 - 0.0018 17.6 0.1 0.0027 17.0 0.1 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 EAQ90579.1 - 0.0071 16.1 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.14 EAQ90579.1 - 0.0092 15.5 0.0 0.014 14.9 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DUF2974 PF11187.8 EAQ90579.1 - 0.015 14.8 0.5 0.69 9.4 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Abhydrolase_8 PF06259.12 EAQ90579.1 - 0.016 14.9 0.1 0.026 14.2 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase Esterase PF00756.20 EAQ90579.1 - 0.19 11.3 0.2 0.31 10.6 0.2 1.2 1 0 0 1 1 1 0 Putative esterase GAS2 PF02187.17 EAQ90580.1 - 8.5e-07 29.0 0.1 1.7e-06 28.0 0.1 1.4 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain Fungal_trans PF04082.18 EAQ90581.1 - 3.3e-28 98.5 0.4 7e-28 97.4 0.1 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EAQ90581.1 - 2.8e-07 30.5 8.6 5.2e-07 29.7 8.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WSC PF01822.19 EAQ90583.1 - 1.5e-71 236.6 60.4 3.2e-19 68.9 10.7 4.6 4 0 0 4 4 4 4 WSC domain peroxidase PF00141.23 EAQ90583.1 - 4.2e-23 82.2 0.0 1e-22 81.0 0.0 1.6 1 0 0 1 1 1 1 Peroxidase PAP2 PF01569.21 EAQ90585.1 - 7.4e-14 51.7 5.2 1.8e-13 50.4 5.2 1.6 1 1 0 1 1 1 1 PAP2 superfamily Peptidase_A24 PF01478.18 EAQ90585.1 - 0.14 12.6 2.2 12 6.4 0.0 2.5 1 1 0 2 2 2 0 Type IV leader peptidase family IBR PF01485.21 EAQ90586.1 - 7.2e-22 77.4 31.0 2.2e-15 56.6 3.2 4.1 3 1 1 4 4 4 3 IBR domain, a half RING-finger domain RWD PF05773.22 EAQ90586.1 - 7.4e-19 68.2 0.0 1.9e-18 66.8 0.0 1.7 2 0 0 2 2 2 1 RWD domain zf-RING_UBOX PF13445.6 EAQ90586.1 - 0.0016 18.4 2.7 0.0016 18.4 2.7 3.8 3 0 0 3 3 3 2 RING-type zinc-finger zf-C3HC4 PF00097.25 EAQ90586.1 - 0.012 15.5 4.2 0.012 15.5 4.2 4.4 3 1 1 4 4 4 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EAQ90586.1 - 0.018 15.2 2.7 0.018 15.2 2.7 4.4 4 1 1 5 5 5 0 zinc finger of C3HC4-type, RING DUF4680 PF15730.5 EAQ90586.1 - 0.24 11.8 2.3 0.5 10.7 2.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4680) NDT80_PhoG PF05224.12 EAQ90588.1 - 2.3e-39 135.6 0.3 5.1e-39 134.4 0.0 1.7 2 0 0 2 2 2 1 NDT80 / PhoG like DNA-binding family DUF3402 PF11882.8 EAQ90589.1 - 1.1e-181 604.9 0.0 5.6e-181 602.7 0.0 2.1 2 1 0 2 2 2 1 Domain of unknown function (DUF3402) N1221 PF07923.13 EAQ90589.1 - 1.1e-71 241.4 0.0 3.2e-39 134.8 0.0 2.3 1 1 1 2 2 2 2 N1221-like protein DUF2011 PF09428.10 EAQ90589.1 - 2.2e-14 53.4 0.0 4.9e-14 52.4 0.0 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2011) FAM176 PF14851.6 EAQ90589.1 - 0.21 11.3 0.2 0.44 10.2 0.2 1.5 1 0 0 1 1 1 0 FAM176 family TRIC PF05197.13 EAQ90590.1 - 0.031 13.8 0.9 0.053 13.1 0.9 1.2 1 0 0 1 1 1 0 TRIC channel Grg1 PF11034.8 EAQ90592.1 - 8.6e-33 112.4 11.1 9.6e-33 112.2 11.1 1.0 1 0 0 1 1 1 1 Glucose-repressible protein Grg1 DnaJ_C PF01556.18 EAQ90595.1 - 2.8e-20 72.9 0.0 4.1e-20 72.4 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EAQ90595.1 - 7.1e-15 54.9 2.4 1.3e-14 54.1 2.4 1.4 1 0 0 1 1 1 1 DnaJ domain Zn_clus PF00172.18 EAQ90596.1 - 4.7e-09 36.2 9.9 9e-09 35.3 9.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EAQ90596.1 - 5.4e-05 22.2 0.1 8.7e-05 21.5 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Rit1_C PF17184.4 EAQ90597.1 - 1.3e-63 215.0 0.0 2.9e-46 158.1 0.0 2.1 1 1 1 2 2 2 2 Rit1 N-terminal domain Init_tRNA_PT PF04179.12 EAQ90597.1 - 2e-36 124.6 0.0 3.3e-36 123.9 0.0 1.4 1 0 0 1 1 1 1 Rit1 DUSP-like domain HAD_2 PF13419.6 EAQ90598.1 - 1.2e-19 71.0 0.0 1.9e-19 70.4 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EAQ90598.1 - 1.2e-13 51.8 0.3 7.8e-13 49.2 0.3 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase NIF PF03031.18 EAQ90598.1 - 1.3e-06 28.3 0.0 3.1e-05 23.8 0.0 2.1 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase Hydrolase_like PF13242.6 EAQ90598.1 - 4.6e-06 26.6 0.0 7.9e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 EAQ90598.1 - 0.0042 17.5 0.0 0.0061 17.0 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase YhfZ_C PF14503.6 EAQ90598.1 - 0.067 12.7 0.0 0.15 11.6 0.0 1.5 2 0 0 2 2 2 0 YhfZ C-terminal domain Hydrolase_6 PF13344.6 EAQ90598.1 - 0.074 13.2 0.0 16 5.7 0.0 2.5 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Thioredoxin PF00085.20 EAQ90600.1 - 1e-62 208.5 0.0 3.4e-30 104.1 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.12 EAQ90600.1 - 1.7e-25 89.7 2.3 1.9e-25 89.6 1.0 1.8 2 0 0 2 2 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.6 EAQ90600.1 - 9.3e-19 67.9 0.0 3.4e-09 37.1 0.0 2.8 2 0 0 2 2 2 2 Thioredoxin-like domain OST3_OST6 PF04756.13 EAQ90600.1 - 4.5e-15 55.8 0.0 5.4e-07 29.2 0.0 2.1 1 1 1 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 EAQ90600.1 - 1.1e-09 38.4 0.1 0.00058 20.0 0.0 3.0 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_8 PF13905.6 EAQ90600.1 - 1.8e-08 34.6 0.0 0.002 18.4 0.0 3.2 2 1 0 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.21 EAQ90600.1 - 5.8e-07 29.5 0.0 0.018 14.9 0.0 2.4 2 0 0 2 2 2 2 AhpC/TSA family ERp29_N PF07912.13 EAQ90600.1 - 1.5e-05 25.1 0.0 0.0065 16.6 0.0 2.5 2 0 0 2 2 2 1 ERp29, N-terminal domain HyaE PF07449.11 EAQ90600.1 - 2.1e-05 24.4 0.0 0.0036 17.3 0.0 2.6 2 0 0 2 2 2 1 Hydrogenase-1 expression protein HyaE Redoxin PF08534.10 EAQ90600.1 - 5.7e-05 22.9 0.8 0.066 12.9 0.1 2.4 1 1 1 2 2 2 2 Redoxin Thioredoxin_9 PF14595.6 EAQ90600.1 - 0.00031 20.5 0.0 0.073 12.9 0.0 2.5 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_6 PF13848.6 EAQ90600.1 - 0.00044 20.2 0.1 0.099 12.5 0.0 3.3 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_3 PF13192.6 EAQ90600.1 - 0.0017 18.4 0.0 1.6 8.9 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin domain TraF PF13728.6 EAQ90600.1 - 0.0024 17.7 0.0 0.46 10.3 0.0 2.5 2 0 0 2 2 2 1 F plasmid transfer operon protein Glutaredoxin PF00462.24 EAQ90600.1 - 0.0073 16.5 1.1 5.4 7.3 0.1 3.2 2 2 0 2 2 2 1 Glutaredoxin Thioredoxin_4 PF13462.6 EAQ90600.1 - 0.038 14.1 3.0 3.8 7.6 0.1 3.6 3 2 2 5 5 5 0 Thioredoxin DSBA PF01323.20 EAQ90600.1 - 0.07 12.9 2.7 32 4.2 0.1 3.9 3 1 1 4 4 4 0 DSBA-like thioredoxin domain Thioredoxin_5 PF13743.6 EAQ90600.1 - 0.13 11.9 0.2 40 3.8 0.0 3.2 2 2 2 4 4 4 0 Thioredoxin Ribosomal_S14 PF00253.21 EAQ90601.1 - 3.4e-16 58.7 3.0 3.7e-16 58.6 3.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e GTP_EFTU PF00009.27 EAQ90602.1 - 4e-57 192.9 0.1 5.3e-57 192.5 0.1 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EAQ90602.1 - 5e-24 84.8 0.0 9.1e-24 83.9 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EAQ90602.1 - 4.4e-15 55.8 2.4 4.4e-15 55.8 2.4 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EAQ90602.1 - 2.4e-05 24.4 0.0 4.3e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EAQ90602.1 - 0.024 14.5 0.1 0.06 13.2 0.0 1.7 2 0 0 2 2 2 0 RsgA GTPase cobW PF02492.19 EAQ90602.1 - 0.025 14.2 0.3 0.13 11.8 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 EAQ90602.1 - 0.083 12.6 0.1 15 5.4 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF2330 PF10092.9 EAQ90603.1 - 0.84 8.7 5.2 0.3 10.1 0.7 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2330) NAD_kinase PF01513.21 EAQ90604.1 - 1e-72 244.8 0.0 2.1e-72 243.8 0.0 1.4 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 EAQ90604.1 - 0.068 12.8 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain PfkB PF00294.24 EAQ90605.1 - 6.9e-16 58.4 0.0 7e-15 55.1 0.0 2.0 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Sacchrp_dh_C PF16653.5 EAQ90607.1 - 4.7e-93 312.1 0.0 1.2e-92 310.8 0.0 1.7 1 1 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 EAQ90607.1 - 8.4e-25 87.5 0.2 1.3e-24 86.9 0.2 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 EAQ90607.1 - 5.5e-05 23.3 0.0 9.9e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.6 EAQ90607.1 - 0.00014 21.9 0.1 0.0003 20.7 0.0 1.7 2 0 0 2 2 2 1 NAD(P)H-binding IlvN PF07991.12 EAQ90607.1 - 0.0014 18.3 0.3 0.031 13.9 0.0 2.7 3 0 0 3 3 3 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain AlaDh_PNT_C PF01262.21 EAQ90607.1 - 0.029 13.7 0.1 0.047 13.0 0.1 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Las1 PF04031.13 EAQ90608.1 - 5.1e-62 208.5 0.0 7.6e-62 208.0 0.0 1.3 1 0 0 1 1 1 1 Las1-like HAGH_C PF16123.5 EAQ90608.1 - 2.5e-15 56.8 0.0 4.7e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 EAQ90608.1 - 0.00017 21.6 0.4 0.00017 21.6 0.4 3.6 2 1 1 3 3 3 1 Metallo-beta-lactamase superfamily EF-hand_9 PF14658.6 EAQ90609.1 - 0.061 13.6 0.0 0.1 12.9 0.0 1.3 1 0 0 1 1 1 0 EF-hand domain IF4E PF01652.18 EAQ90610.1 - 7.5e-38 129.8 0.2 1e-37 129.4 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E DUF4598 PF15370.6 EAQ90611.1 - 1.2e-08 35.4 0.4 3.3e-08 34.0 0.4 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4598) DTHCT PF08070.11 EAQ90611.1 - 0.16 12.7 5.8 0.35 11.6 5.2 2.0 1 1 0 1 1 1 0 DTHCT (NUC029) region Kinesin PF00225.23 EAQ90612.1 - 2.4e-104 348.9 0.0 3.4e-104 348.4 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain PUL PF08324.11 EAQ90612.1 - 6.5e-57 192.9 0.0 1e-56 192.3 0.0 1.2 1 0 0 1 1 1 1 PUL domain Microtub_bd PF16796.5 EAQ90612.1 - 1.4e-25 89.9 0.0 2.5e-25 89.2 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding Peptidase_C97 PF05903.14 EAQ90612.1 - 4.5e-17 62.3 0.0 8.5e-17 61.4 0.0 1.5 1 0 0 1 1 1 1 PPPDE putative peptidase domain Thioredoxin PF00085.20 EAQ90612.1 - 1.5e-12 47.4 0.0 3.1e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 EAQ90612.1 - 0.0073 16.2 0.0 0.042 13.8 0.0 2.0 2 0 0 2 2 2 1 AhpC/TSA family Thioredoxin_2 PF13098.6 EAQ90612.1 - 0.0097 16.4 0.2 0.12 12.8 0.2 2.6 1 1 0 1 1 1 1 Thioredoxin-like domain TraF PF13728.6 EAQ90612.1 - 0.057 13.2 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 F plasmid transfer operon protein Redoxin PF08534.10 EAQ90612.1 - 0.17 11.6 0.0 0.35 10.6 0.0 1.4 1 0 0 1 1 1 0 Redoxin Thioredoxin_3 PF13192.6 EAQ90612.1 - 0.2 11.7 0.0 0.72 9.9 0.0 1.9 2 0 0 2 2 2 0 Thioredoxin domain GDA1_CD39 PF01150.17 EAQ90613.1 - 6.3e-99 331.5 0.0 7.7e-99 331.2 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family AAA_lid_2 PF17863.1 EAQ90614.1 - 1.3e-06 28.1 1.6 3.2e-06 26.9 1.6 1.6 1 0 0 1 1 1 1 AAA lid domain AAA_3 PF07726.11 EAQ90614.1 - 0.019 14.8 0.0 0.033 14.0 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Ras PF00071.22 EAQ90615.1 - 1.9e-57 193.4 0.0 2.2e-57 193.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAQ90615.1 - 4.6e-32 110.8 0.0 6.5e-32 110.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAQ90615.1 - 2e-13 50.2 0.0 2.4e-13 49.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EAQ90615.1 - 3.4e-08 33.6 0.0 5.6e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EAQ90615.1 - 3e-06 26.8 0.0 3.7e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EAQ90615.1 - 4.4e-05 23.1 0.1 0.0014 18.2 0.1 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EAQ90615.1 - 9e-05 22.4 0.1 0.0035 17.3 0.1 2.4 1 1 2 3 3 3 1 RsgA GTPase SRPRB PF09439.10 EAQ90615.1 - 0.0032 16.9 0.0 0.0041 16.6 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 EAQ90615.1 - 0.0053 16.5 0.1 0.11 12.2 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_5 PF07728.14 EAQ90615.1 - 0.0062 16.5 0.0 0.011 15.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EAQ90615.1 - 0.0098 16.3 0.0 0.016 15.6 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain cobW PF02492.19 EAQ90615.1 - 0.01 15.5 0.0 0.026 14.1 0.0 1.6 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 EAQ90615.1 - 0.013 15.8 0.0 0.021 15.1 0.0 1.5 1 1 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 EAQ90615.1 - 0.014 15.2 0.2 0.42 10.3 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Septin PF00735.18 EAQ90615.1 - 0.017 14.4 0.2 0.04 13.2 0.0 1.7 3 0 0 3 3 3 0 Septin NTPase_1 PF03266.15 EAQ90615.1 - 0.019 14.9 0.0 0.027 14.4 0.0 1.3 1 0 0 1 1 1 0 NTPase AAA_24 PF13479.6 EAQ90615.1 - 0.021 14.6 0.0 0.041 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EAQ90615.1 - 0.023 14.2 0.1 0.038 13.5 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region NB-ARC PF00931.22 EAQ90615.1 - 0.047 12.9 0.1 0.22 10.7 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain ATPase_2 PF01637.18 EAQ90615.1 - 0.059 13.3 0.2 0.14 12.1 0.0 1.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea TniB PF05621.11 EAQ90615.1 - 0.12 11.8 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein NACHT PF05729.12 EAQ90615.1 - 0.12 12.2 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.22 EAQ90615.1 - 0.14 12.5 0.0 0.49 10.8 0.0 1.9 2 0 0 2 2 2 0 RNA helicase DAP3 PF10236.9 EAQ90615.1 - 0.18 11.0 0.2 0.25 10.5 0.2 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_21 PF13304.6 EAQ90615.1 - 0.2 11.4 1.0 2.5 7.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF3955 PF13127.6 EAQ90616.1 - 1.2e-14 53.8 2.1 1.2e-14 53.8 2.1 2.7 4 0 0 4 4 4 1 Protein of unknown function (DUF3955) EamA PF00892.20 EAQ90616.1 - 3.5e-07 30.5 36.6 0.00011 22.3 4.9 3.1 3 0 0 3 3 3 2 EamA-like transporter family PUNUT PF16913.5 EAQ90616.1 - 2.8e-05 23.5 1.0 2.8e-05 23.5 1.0 1.8 3 0 0 3 3 3 1 Purine nucleobase transmembrane transport UAA PF08449.11 EAQ90616.1 - 5.7e-05 22.5 10.8 8.8e-05 21.9 10.8 1.2 1 0 0 1 1 1 1 UAA transporter family SLC35F PF06027.12 EAQ90616.1 - 0.0001 21.9 11.8 0.0001 21.9 11.8 1.9 2 0 0 2 2 2 1 Solute carrier family 35 WD40 PF00400.32 EAQ90617.1 - 3.3e-09 37.2 2.8 0.12 13.3 0.1 4.9 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAQ90617.1 - 6.3e-05 23.2 0.0 0.019 15.2 0.0 4.1 4 1 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain VID27 PF08553.10 EAQ90617.1 - 0.032 13.3 0.0 0.049 12.7 0.0 1.2 1 0 0 1 1 1 0 VID27 C-terminal WD40-like domain Spb1_C PF07780.12 EAQ90618.1 - 1.1e-88 296.4 21.2 1.1e-88 296.4 21.2 2.7 3 0 0 3 3 3 1 Spb1 C-terminal domain FtsJ PF01728.19 EAQ90618.1 - 2.1e-57 194.1 0.0 3.7e-57 193.3 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.8 EAQ90618.1 - 5.7e-51 172.6 13.1 5.7e-51 172.6 13.1 4.3 3 1 1 4 4 4 1 Domain of unknown function (DUF3381) Methyltransf_23 PF13489.6 EAQ90618.1 - 0.0094 15.8 0.0 0.025 14.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltr_RsmB-F PF01189.17 EAQ90618.1 - 0.074 12.7 0.0 0.074 12.7 0.0 2.0 2 0 0 2 2 2 0 16S rRNA methyltransferase RsmB/F Sterol-sensing PF12349.8 EAQ90619.1 - 1.8e-41 141.6 10.2 2.9e-41 140.8 10.2 1.4 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 EAQ90619.1 - 4.3e-11 41.7 2.4 5.9e-11 41.2 2.4 1.2 1 0 0 1 1 1 1 Patched family Dimer_Tnp_hAT PF05699.14 EAQ90620.1 - 2.8e-13 49.4 0.2 6.5e-13 48.3 0.2 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region 14-3-3 PF00244.20 EAQ90623.1 - 6.5e-08 32.4 0.1 4.5e-07 29.6 0.0 2.0 2 0 0 2 2 2 1 14-3-3 protein Collagen PF01391.18 EAQ90623.1 - 0.0097 15.6 6.6 0.0097 15.6 6.6 2.1 2 0 0 2 2 2 1 Collagen triple helix repeat (20 copies) Adenine_deam_C PF13382.6 EAQ90624.1 - 0.21 10.9 0.0 0.3 10.4 0.0 1.1 1 0 0 1 1 1 0 Adenine deaminase C-terminal domain DUF4202 PF13875.6 EAQ90625.1 - 1.6e-69 233.6 0.0 1.8e-69 233.4 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4202) Med5 PF08689.10 EAQ90626.1 - 1.1e-51 175.8 0.0 3.3e-33 114.7 0.0 3.1 2 1 1 3 3 3 3 Mediator complex subunit Med5 Phage_HK97_TLTM PF06120.11 EAQ90626.1 - 0.42 9.8 1.4 0.68 9.1 1.4 1.2 1 0 0 1 1 1 0 Tail length tape measure protein OAD_gamma PF04277.13 EAQ90626.1 - 0.52 10.9 3.2 15 6.2 0.0 2.6 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain CRISPR_Cse2 PF09485.10 EAQ90626.1 - 7.7 7.0 6.2 35 4.9 0.2 3.5 3 0 0 3 3 3 0 CRISPR-associated protein Cse2 (CRISPR_cse2) TRAP_alpha PF03896.16 EAQ90629.1 - 0.016 14.5 0.3 0.063 12.5 0.3 2.0 1 1 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Dynamin_N PF00350.23 EAQ90630.1 - 3.4e-42 144.4 0.0 8.8e-42 143.0 0.0 1.7 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 EAQ90630.1 - 2.2e-09 37.0 0.1 1.2e-08 34.6 0.1 2.0 1 1 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.23 EAQ90630.1 - 8.7e-06 25.8 0.3 0.00015 21.8 0.0 2.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 EAQ90630.1 - 0.012 16.0 0.4 0.071 13.5 0.0 2.4 2 1 0 2 2 2 0 AAA ATPase domain AAA_15 PF13175.6 EAQ90630.1 - 0.044 13.5 0.6 0.16 11.6 0.1 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_21 PF13304.6 EAQ90630.1 - 0.048 13.5 0.0 0.084 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system GATase_4 PF13230.6 EAQ90631.1 - 5.5e-15 55.0 0.0 1.9e-14 53.2 0.0 1.9 3 0 0 3 3 3 1 Glutamine amidotransferases class-II GATase_6 PF13522.6 EAQ90631.1 - 4.8e-08 33.3 0.0 8.4e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain Cation_efflux PF01545.21 EAQ90632.1 - 4.9e-11 42.7 5.5 7.3e-11 42.2 5.5 1.2 1 0 0 1 1 1 1 Cation efflux family PIG-Y PF15159.6 EAQ90633.1 - 3.9e-21 75.7 8.1 6e-21 75.1 8.1 1.3 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y HPHLAWLY PF14925.6 EAQ90633.1 - 0.23 10.1 0.2 0.42 9.2 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function Pkinase PF00069.25 EAQ90634.1 - 1.6e-17 63.8 0.0 3.4e-14 52.9 0.0 2.9 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ90634.1 - 2e-15 56.8 0.1 1.5e-11 44.0 0.0 3.9 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 EAQ90634.1 - 0.022 13.6 0.6 0.048 12.4 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase SpecificRecomb PF10136.9 EAQ90634.1 - 0.075 11.3 0.4 0.11 10.8 0.4 1.1 1 0 0 1 1 1 0 Site-specific recombinase zf-MYND PF01753.18 EAQ90635.1 - 5e-08 32.9 19.6 1.3e-07 31.6 19.6 1.7 1 0 0 1 1 1 1 MYND finger zf-TAZ PF02135.16 EAQ90635.1 - 0.24 11.9 8.5 0.43 11.1 8.5 1.4 1 0 0 1 1 1 0 TAZ zinc finger Ebp2 PF05890.12 EAQ90636.1 - 2.3e-91 306.1 12.5 2.3e-91 306.1 12.5 1.9 2 0 0 2 2 2 1 Eukaryotic rRNA processing protein EBP2 HrpA_pilin PF09589.10 EAQ90636.1 - 0.022 15.4 3.2 0.11 13.2 3.2 2.2 1 0 0 1 1 1 0 HrpA pilus formation protein HHA PF05321.11 EAQ90636.1 - 2.8 8.3 4.7 2 8.8 0.3 2.7 3 0 0 3 3 3 0 Haemolysin expression modulating protein DUF1768 PF08719.11 EAQ90636.1 - 6.6 6.9 10.1 0.6 10.3 5.0 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF1768) HTH_31 PF13560.6 EAQ90637.1 - 1.8e-05 25.0 0.1 2.5e-05 24.5 0.1 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 EAQ90637.1 - 0.0052 16.8 0.0 0.0089 16.1 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_AsnC-type PF13404.6 EAQ90637.1 - 0.14 12.0 0.6 5.8 6.8 0.0 2.5 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Sigma70_r4_2 PF08281.12 EAQ90637.1 - 0.15 11.7 0.1 0.48 10.2 0.0 1.8 2 0 0 2 2 2 0 Sigma-70, region 4 MMR_HSR1 PF01926.23 EAQ90639.1 - 4.3e-09 36.4 0.0 1.4e-08 34.8 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 EAQ90639.1 - 5.6e-06 25.8 0.0 1.2e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 AIG1 family FeoB_N PF02421.18 EAQ90639.1 - 0.0013 18.3 0.0 0.0056 16.2 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EAQ90639.1 - 0.0032 17.4 0.2 0.0032 17.4 0.2 2.1 2 1 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 EAQ90639.1 - 0.0052 16.9 10.3 0.25 11.4 0.0 3.6 2 2 1 3 3 3 2 Dynamin family AAA_22 PF13401.6 EAQ90639.1 - 0.0056 16.9 2.1 0.031 14.6 0.0 2.6 2 1 0 2 2 2 1 AAA domain ABC_tran PF00005.27 EAQ90639.1 - 0.012 16.1 4.1 0.015 15.9 0.0 2.7 2 1 0 2 2 2 0 ABC transporter GBP PF02263.19 EAQ90639.1 - 0.013 14.8 0.0 0.023 14.0 0.0 1.4 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain AAA_18 PF13238.6 EAQ90639.1 - 0.017 15.6 0.0 0.017 15.6 0.0 2.3 2 1 0 2 2 1 0 AAA domain DUF87 PF01935.17 EAQ90639.1 - 0.03 14.4 0.2 0.03 14.4 0.2 2.4 2 1 0 2 2 2 0 Helicase HerA, central domain AAA_29 PF13555.6 EAQ90639.1 - 0.033 13.9 0.0 0.068 12.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain IIGP PF05049.13 EAQ90639.1 - 0.061 12.4 2.6 0.38 9.7 0.0 2.3 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) SRP54 PF00448.22 EAQ90639.1 - 0.078 12.6 0.1 0.078 12.6 0.1 2.3 2 1 0 2 2 2 0 SRP54-type protein, GTPase domain SRPRB PF09439.10 EAQ90639.1 - 0.095 12.1 1.7 0.2 11.1 0.0 2.2 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit CLP1_P PF16575.5 EAQ90639.1 - 0.15 11.8 0.2 0.59 9.9 0.0 2.1 3 0 0 3 3 3 0 mRNA cleavage and polyadenylation factor CLP1 P-loop ATP_bind_1 PF03029.17 EAQ90639.1 - 1.4 8.6 5.3 0.37 10.5 0.1 2.5 2 1 1 3 3 3 0 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 EAQ90640.1 - 1.5e-07 31.5 0.6 3.9e-07 30.1 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_18 PF13238.6 EAQ90640.1 - 0.00073 20.1 4.1 0.0016 19.0 0.0 2.7 2 1 0 2 2 2 1 AAA domain Septin PF00735.18 EAQ90640.1 - 0.002 17.5 0.6 0.0055 16.0 0.0 2.0 2 0 0 2 2 2 1 Septin RsgA_GTPase PF03193.16 EAQ90640.1 - 0.0028 17.6 0.4 0.0028 17.6 0.4 2.0 2 0 0 2 2 2 1 RsgA GTPase AIG1 PF04548.16 EAQ90640.1 - 0.009 15.4 0.0 0.009 15.4 0.0 2.1 2 0 0 2 2 2 1 AIG1 family AAA_24 PF13479.6 EAQ90640.1 - 0.018 14.7 0.1 0.046 13.4 0.1 1.7 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 EAQ90640.1 - 0.033 14.2 0.0 0.11 12.5 0.0 1.9 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Viral_helicase1 PF01443.18 EAQ90640.1 - 0.039 13.7 0.0 0.076 12.8 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase SRP54 PF00448.22 EAQ90640.1 - 0.047 13.3 0.3 0.25 11.0 0.2 2.2 1 1 1 2 2 2 0 SRP54-type protein, GTPase domain Dynamin_N PF00350.23 EAQ90640.1 - 0.067 13.3 0.1 0.067 13.3 0.1 3.9 2 2 1 3 3 2 0 Dynamin family NACHT PF05729.12 EAQ90640.1 - 0.11 12.4 1.2 0.26 11.2 0.0 2.1 2 0 0 2 2 2 0 NACHT domain ATPase PF06745.13 EAQ90640.1 - 0.13 11.6 0.1 0.13 11.6 0.1 2.6 2 1 1 3 3 3 0 KaiC AAA_22 PF13401.6 EAQ90640.1 - 0.5 10.6 0.1 0.5 10.6 0.1 2.6 2 2 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EAQ90640.1 - 0.7 10.0 0.0 0.7 10.0 0.0 3.0 2 1 0 2 2 2 0 AAA domain Vfa1 PF08432.10 EAQ90640.1 - 1.9 8.8 17.7 4 7.7 17.7 1.5 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 cobW PF02492.19 EAQ90640.1 - 9.8 5.7 6.8 0.78 9.3 0.2 2.6 4 1 0 4 4 4 0 CobW/HypB/UreG, nucleotide-binding domain SAPS PF04499.15 EAQ90641.1 - 4.7 5.9 5.4 5.8 5.6 5.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein B-block_TFIIIC PF04182.12 EAQ90642.1 - 1.4e-16 60.4 0.0 7.7e-16 58.0 0.0 2.3 3 0 0 3 3 3 1 B-block binding subunit of TFIIIC UQ_con PF00179.26 EAQ90643.1 - 1.8e-18 66.5 0.0 2.5e-18 66.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme zf-C2H2_4 PF13894.6 EAQ90644.1 - 5.7e-13 48.5 13.7 0.017 15.9 0.9 5.4 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2 PF00096.26 EAQ90644.1 - 0.00061 20.1 13.0 0.025 15.0 0.7 4.7 5 0 0 5 5 5 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 EAQ90644.1 - 0.006 16.8 2.4 46 4.4 0.0 4.4 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 EAQ90644.1 - 0.026 14.5 15.7 0.9 9.6 0.2 4.8 5 0 0 5 5 5 0 C2H2-type zinc finger zf-C2H2_2 PF12756.7 EAQ90644.1 - 0.032 14.6 9.8 2.4 8.6 1.3 3.8 2 2 2 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.6 EAQ90644.1 - 0.041 14.3 0.2 0.041 14.3 0.2 4.3 4 0 0 4 4 4 0 Zinc-finger double domain zf-C2H2_9 PF16293.5 EAQ90644.1 - 0.11 12.3 6.4 3.1 7.7 0.1 3.5 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) zinc-ribbons_6 PF07191.12 EAQ90644.1 - 0.23 11.5 6.7 0.15 12.1 2.5 2.4 2 0 0 2 2 2 0 zinc-ribbons DHHC PF01529.20 EAQ90645.1 - 3.7e-39 133.9 8.4 3.7e-39 133.9 8.4 1.9 2 0 0 2 2 2 1 DHHC palmitoyltransferase Pex14_N PF04695.13 EAQ90645.1 - 0.039 14.6 1.9 0.095 13.4 1.3 1.9 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region YL1 PF05764.13 EAQ90645.1 - 0.096 12.8 3.6 0.18 11.9 3.6 1.4 1 0 0 1 1 1 0 YL1 nuclear protein DUF4064 PF13273.6 EAQ90645.1 - 0.21 11.9 0.0 0.21 11.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) FtsX PF02687.21 EAQ90645.1 - 0.77 10.3 6.1 4.3 7.9 6.1 2.1 1 1 0 1 1 1 0 FtsX-like permease family Spt20 PF12090.8 EAQ90645.1 - 7 6.2 10.3 15 5.1 10.3 1.5 1 0 0 1 1 1 0 Spt20 family DUF4124 PF13511.6 EAQ90645.1 - 8.5 6.8 8.8 26 5.2 8.8 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4124) CDC45 PF02724.14 EAQ90645.1 - 8.8 4.5 5.4 17 3.6 5.4 1.3 1 0 0 1 1 1 0 CDC45-like protein PI-PLC-X PF00388.19 EAQ90646.1 - 5e-58 194.8 0.0 1e-57 193.8 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 EAQ90646.1 - 6.6e-43 145.7 0.0 1.6e-42 144.5 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 EAQ90646.1 - 1.1e-07 32.1 0.0 3.3e-07 30.5 0.0 1.9 1 0 0 1 1 1 1 C2 domain EF-hand_like PF09279.11 EAQ90646.1 - 0.0023 18.4 0.0 0.008 16.6 0.0 1.9 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like PH_12 PF16457.5 EAQ90646.1 - 0.017 15.6 0.1 0.044 14.3 0.1 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain SinI PF08671.10 EAQ90646.1 - 0.11 12.4 0.0 0.56 10.0 0.0 2.1 2 0 0 2 2 2 0 Anti-repressor SinI Zw10 PF06248.13 EAQ90650.1 - 1e-08 34.3 2.1 0.00021 20.0 2.0 2.2 2 0 0 2 2 2 2 Centromere/kinetochore Zw10 Dsl1_C PF11989.8 EAQ90650.1 - 0.0055 16.5 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 Retrograde transport protein Dsl1 C terminal Ribosomal_L36e PF01158.18 EAQ90651.1 - 3.7e-41 139.3 6.7 4.2e-41 139.1 6.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e MRP-L28 PF09812.9 EAQ90651.1 - 0.0034 17.5 1.3 0.0042 17.2 1.3 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 LemA PF04011.12 EAQ90651.1 - 0.037 13.9 0.2 0.044 13.6 0.2 1.2 1 0 0 1 1 1 0 LemA family PBS_linker_poly PF00427.21 EAQ90651.1 - 0.078 13.0 0.2 0.089 12.8 0.2 1.1 1 0 0 1 1 1 0 Phycobilisome Linker polypeptide Peptidase_M16_C PF05193.21 EAQ90652.1 - 2.3e-19 70.1 0.0 5.8e-15 55.8 0.0 2.8 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EAQ90652.1 - 2.8e-05 24.1 0.0 7.4e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) M16C_assoc PF08367.11 EAQ90652.1 - 0.0057 15.8 4.8 0.089 11.9 4.8 2.2 1 1 0 1 1 1 1 Peptidase M16C associated RQC PF09382.10 EAQ90652.1 - 0.082 12.7 0.0 0.29 10.9 0.0 2.0 1 0 0 1 1 1 0 RQC domain Sporozoite_P67 PF05642.11 EAQ90652.1 - 0.12 10.5 2.4 0.17 10.0 2.4 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PhetRS_B1 PF18262.1 EAQ90652.1 - 0.35 11.1 1.4 1 9.6 1.4 1.8 1 0 0 1 1 1 0 Phe-tRNA synthetase beta subunit B1 domain ATG16 PF08614.11 EAQ90653.1 - 0.021 15.1 1.4 0.034 14.4 1.4 1.4 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Acetyltransf_1 PF00583.25 EAQ90654.1 - 2.4e-13 50.3 0.0 3.7e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EAQ90654.1 - 9.5e-10 38.8 0.0 1.4e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EAQ90654.1 - 1.8e-09 37.6 0.0 2.9e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EAQ90654.1 - 5.2e-06 26.3 0.0 9.2e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 EAQ90654.1 - 0.0013 18.8 0.0 0.0017 18.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EAQ90654.1 - 0.0061 16.7 0.2 0.019 15.1 0.2 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain NMO PF03060.15 EAQ90655.1 - 3.3e-37 128.6 8.2 4.8e-37 128.1 8.2 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 EAQ90655.1 - 2.9e-07 29.8 3.9 1.1e-06 27.9 3.7 1.8 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 EAQ90655.1 - 0.077 12.0 7.9 0.13 11.3 7.9 1.3 1 0 0 1 1 1 0 FMN-dependent dehydrogenase Pneumo_att_G PF05539.11 EAQ90656.1 - 4.2 6.9 6.1 6.2 6.3 6.1 1.3 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Taxilin PF09728.9 EAQ90657.1 - 1.7e-85 286.9 57.7 1.2e-84 284.1 57.7 2.2 1 1 0 1 1 1 1 Myosin-like coiled-coil protein DUF2203 PF09969.9 EAQ90657.1 - 0.019 15.7 0.9 0.019 15.7 0.9 4.2 3 1 2 5 5 5 0 Uncharacterized conserved protein (DUF2203) MAD PF05557.13 EAQ90657.1 - 0.27 9.5 56.2 0.15 10.4 23.7 2.1 2 0 0 2 2 2 0 Mitotic checkpoint protein DUF4810 PF16068.5 EAQ90657.1 - 0.32 11.6 0.0 0.32 11.6 0.0 4.0 5 0 0 5 5 5 0 Domain of unknown function (DUF4810) TMF_TATA_bd PF12325.8 EAQ90657.1 - 1.9 8.7 55.5 4.4 7.6 4.6 4.7 2 2 1 4 4 4 0 TATA element modulatory factor 1 TATA binding PRKG1_interact PF15898.5 EAQ90657.1 - 2 9.4 49.9 0.21 12.5 10.3 4.5 2 2 2 4 4 4 0 cGMP-dependent protein kinase interacting domain TSC22 PF01166.18 EAQ90657.1 - 4.9 7.5 18.7 4.3 7.7 1.3 4.8 4 0 0 4 4 4 0 TSC-22/dip/bun family Prominin PF05478.11 EAQ90657.1 - 8.1 4.3 23.8 0.9 7.4 5.7 2.3 2 0 0 2 2 2 0 Prominin M16C_assoc PF08367.11 EAQ90658.1 - 9.8e-81 270.6 0.1 1.5e-80 270.0 0.1 1.3 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 EAQ90658.1 - 3.1e-34 118.6 0.0 3.6e-23 82.5 0.0 3.0 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EAQ90658.1 - 0.0014 18.6 0.1 0.085 12.8 0.0 2.7 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) HHH_8 PF14716.6 EAQ90658.1 - 0.06 13.7 0.0 0.56 10.6 0.0 2.6 3 0 0 3 3 3 0 Helix-hairpin-helix domain Orn_Arg_deC_N PF02784.16 EAQ90659.1 - 1.4e-84 283.3 0.0 1.9e-84 282.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 EAQ90659.1 - 8.9e-22 77.2 0.0 1.2e-21 76.8 0.0 1.3 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Pribosyl_synth PF14572.6 EAQ90660.1 - 2.6e-40 138.4 1.6 4.7e-34 118.0 0.5 2.3 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 EAQ90660.1 - 3.5e-28 97.9 0.0 1.1e-27 96.3 0.0 1.8 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 EAQ90660.1 - 1.6e-13 50.5 0.5 3e-13 49.6 0.5 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain SUIM_assoc PF16619.5 EAQ90660.1 - 0.16 12.1 4.6 1.2 9.2 0.1 2.4 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Sugar_tr PF00083.24 EAQ90661.1 - 3.6e-68 230.5 14.1 7.7e-63 212.9 6.0 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EAQ90661.1 - 9.8e-14 51.0 24.0 1.3e-11 44.0 11.5 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily PTPS_related PF10131.9 EAQ90661.1 - 0.02 13.2 1.7 0.021 13.2 0.5 1.5 2 0 0 2 2 2 0 6-pyruvoyl-tetrahydropterin synthase related domain; membrane protein TRI12 PF06609.13 EAQ90661.1 - 0.23 9.8 4.2 0.29 9.5 0.8 2.1 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) VIT1 PF01988.19 EAQ90661.1 - 3.5 7.4 7.1 0.23 11.3 0.7 2.2 2 1 0 2 2 2 0 VIT family WD40 PF00400.32 EAQ90662.1 - 1.2e-21 76.5 12.6 5.8e-05 23.8 0.4 6.8 6 1 1 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAQ90662.1 - 4.9e-14 52.4 5.5 1.1e-05 25.7 0.4 4.8 3 2 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EAQ90662.1 - 5.3e-06 26.4 0.1 0.1 12.5 0.0 2.5 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 EAQ90662.1 - 0.018 14.0 0.0 0.15 11.0 0.0 2.0 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein tRNA_anti-like PF12869.7 EAQ90662.1 - 0.23 11.1 0.1 0.43 10.2 0.1 1.3 1 0 0 1 1 1 0 tRNA_anti-like DUF2838 PF10998.8 EAQ90663.1 - 3.3e-46 156.1 11.6 3.3e-46 156.1 11.6 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF2838) Tropomyosin_1 PF12718.7 EAQ90663.1 - 0.0069 16.5 0.7 0.013 15.7 0.7 1.3 1 0 0 1 1 1 1 Tropomyosin like Val_tRNA-synt_C PF10458.9 EAQ90663.1 - 0.73 10.2 2.9 28 5.1 1.0 2.3 2 0 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm SMC_N PF02463.19 EAQ90664.1 - 9.5e-43 146.2 0.0 3.4e-42 144.4 0.0 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 EAQ90664.1 - 1.4e-25 89.8 0.0 6.8e-25 87.6 0.0 2.3 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 EAQ90664.1 - 0.00011 22.1 0.2 0.00011 22.1 0.2 3.2 3 1 1 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system Spc7 PF08317.11 EAQ90664.1 - 0.003 16.5 112.8 0.034 13.0 18.5 7.2 3 2 4 7 7 7 6 Spc7 kinetochore protein ATG16 PF08614.11 EAQ90664.1 - 0.0033 17.7 108.2 0.035 14.3 5.8 7.7 3 2 2 6 6 6 4 Autophagy protein 16 (ATG16) MscS_porin PF12795.7 EAQ90664.1 - 0.0047 16.5 20.5 0.0047 16.5 20.5 7.2 3 2 2 6 6 6 2 Mechanosensitive ion channel porin domain SbcCD_C PF13558.6 EAQ90664.1 - 0.0085 16.3 0.0 0.061 13.6 0.0 2.6 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Laminin_II PF06009.12 EAQ90664.1 - 2.2 8.3 69.0 0.087 12.8 4.1 8.3 4 2 4 8 8 8 0 Laminin Domain II TFIIE_alpha PF02002.17 EAQ90665.1 - 3.9e-15 55.6 0.1 6.9e-15 54.8 0.1 1.4 1 0 0 1 1 1 1 TFIIE alpha subunit TF_Zn_Ribbon PF08271.12 EAQ90665.1 - 0.0051 16.3 0.1 0.011 15.2 0.1 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding zf-Dof PF02701.15 EAQ90665.1 - 0.013 15.6 0.4 0.027 14.6 0.4 1.5 1 0 0 1 1 1 0 Dof domain, zinc finger zf-HIT PF04438.16 EAQ90665.1 - 0.036 13.9 1.4 2.2 8.2 0.3 2.2 2 0 0 2 2 2 0 HIT zinc finger Elf1 PF05129.13 EAQ90665.1 - 0.046 13.8 0.1 0.09 12.8 0.1 1.4 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like zf-RRN7 PF11781.8 EAQ90665.1 - 0.077 12.7 0.4 0.077 12.7 0.4 1.7 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zf_UBZ PF18439.1 EAQ90665.1 - 0.078 12.6 1.7 7.9 6.2 0.1 2.4 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Zn_Tnp_IS1595 PF12760.7 EAQ90665.1 - 0.12 12.3 1.1 0.31 11.1 1.1 1.6 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-ribbon_3 PF13248.6 EAQ90665.1 - 0.13 11.7 0.2 5.5 6.6 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 EAQ90665.1 - 0.17 12.1 1.8 0.55 10.4 1.4 2.1 1 1 2 3 3 3 0 Zinc ribbon domain DNA_pol_lambd_f PF10391.9 EAQ90666.1 - 3.8e-21 74.6 1.1 1.1e-20 73.1 0.5 2.2 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda DNA_pol_B_thumb PF14791.6 EAQ90666.1 - 5.4e-20 71.3 0.1 1.4e-19 70.0 0.1 1.8 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_B_palm PF14792.6 EAQ90666.1 - 6.5e-20 71.4 0.0 1.3e-19 70.5 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase beta palm HHH_5 PF14520.6 EAQ90666.1 - 0.022 15.3 0.0 0.17 12.5 0.0 2.3 2 0 0 2 2 2 0 Helix-hairpin-helix domain HHH_8 PF14716.6 EAQ90666.1 - 0.032 14.6 0.0 0.34 11.3 0.0 2.5 1 1 0 1 1 1 0 Helix-hairpin-helix domain NTP_transf_2 PF01909.23 EAQ90666.1 - 0.042 14.1 0.1 0.36 11.2 0.0 2.5 3 0 0 3 3 3 0 Nucleotidyltransferase domain MAPEG PF01124.18 EAQ90667.1 - 1.7e-27 95.8 1.5 2e-27 95.6 1.5 1.1 1 0 0 1 1 1 1 MAPEG family Sec23_trunk PF04811.15 EAQ90669.1 - 3e-80 269.3 0.0 4.2e-80 268.8 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 EAQ90669.1 - 2.5e-31 108.3 0.2 5.5e-31 107.2 0.2 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 EAQ90669.1 - 2.9e-25 88.1 0.4 6.8e-25 86.9 0.1 1.9 2 0 0 2 2 2 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 EAQ90669.1 - 6.4e-16 58.1 6.1 1.2e-15 57.3 6.1 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 EAQ90669.1 - 3e-13 49.5 0.0 7.5e-13 48.2 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 EAQ90669.1 - 0.034 13.5 0.6 0.078 12.4 0.1 1.8 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain VWA_2 PF13519.6 EAQ90669.1 - 0.14 12.8 0.0 10 6.9 0.0 2.7 1 1 0 2 2 2 0 von Willebrand factor type A domain Ribosomal_L11_N PF03946.14 EAQ90670.1 - 7.6e-25 86.5 0.2 1.3e-24 85.8 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 EAQ90670.1 - 2.5e-16 60.0 0.1 4.2e-16 59.2 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Glyco_transf_41 PF13844.6 EAQ90672.1 - 1.3e-81 274.5 0.0 6.3e-49 166.7 0.0 4.1 2 2 2 4 4 4 4 Glycosyl transferase family 41 TPR_1 PF00515.28 EAQ90672.1 - 6.2e-23 79.6 5.7 0.00012 21.8 0.0 7.7 7 1 1 8 8 8 5 Tetratricopeptide repeat TPR_2 PF07719.17 EAQ90672.1 - 8.6e-18 63.0 8.6 0.00049 20.0 0.0 7.6 7 1 1 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.6 EAQ90672.1 - 3.7e-16 57.9 0.4 0.0078 16.4 0.0 6.0 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.6 EAQ90672.1 - 1.1e-15 56.9 5.5 0.0025 17.5 0.2 7.3 4 2 3 7 7 7 5 TPR repeat TPR_12 PF13424.6 EAQ90672.1 - 2.3e-10 40.6 6.9 0.25 11.6 0.0 6.1 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 EAQ90672.1 - 9.6e-10 38.2 0.8 0.0019 18.5 0.0 4.7 5 0 0 5 5 3 3 Tetratricopeptide repeat TPR_10 PF13374.6 EAQ90672.1 - 2e-09 37.0 11.5 0.0026 17.6 0.8 6.9 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 EAQ90672.1 - 3.4e-08 33.0 5.4 0.12 12.5 0.1 5.7 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_16 PF13432.6 EAQ90672.1 - 1.1e-06 29.2 12.4 0.0074 16.9 0.3 6.3 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_14 PF13428.6 EAQ90672.1 - 3e-06 27.6 11.4 0.0096 16.7 0.2 6.3 6 2 2 8 8 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 EAQ90672.1 - 2.8e-05 24.5 2.6 1.4 9.4 0.1 4.6 4 1 0 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 EAQ90672.1 - 0.0027 17.8 0.7 1.5 9.0 0.0 3.6 2 1 1 3 3 3 1 Tetratricopeptide repeat BTAD PF03704.17 EAQ90672.1 - 0.0035 17.8 2.0 0.27 11.7 0.0 3.2 3 0 0 3 3 3 1 Bacterial transcriptional activator domain TPR_6 PF13174.6 EAQ90672.1 - 0.0073 16.9 1.0 20 6.1 0.2 4.8 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_15 PF13429.6 EAQ90672.1 - 0.029 13.6 0.0 0.29 10.3 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Myb_DNA-binding PF00249.31 EAQ90673.1 - 2e-19 69.5 1.3 1.6e-10 41.0 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAQ90673.1 - 3.6e-16 59.1 0.2 8.4e-11 42.0 0.0 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain HTH_23 PF13384.6 EAQ90673.1 - 0.11 12.4 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain SANT_DAMP1_like PF16282.5 EAQ90673.1 - 0.13 12.5 0.0 12 6.2 0.0 2.2 1 1 1 2 2 2 0 SANT/Myb-like domain of DAMP1 MADF_DNA_bdg PF10545.9 EAQ90673.1 - 0.71 10.2 4.5 0.89 9.9 1.9 2.1 1 1 1 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Orthopox_F8 PF05886.11 EAQ90673.1 - 0.87 9.8 4.9 0.34 11.1 1.6 2.0 2 0 0 2 2 2 0 Orthopoxvirus F8 protein 2-ph_phosp PF04029.14 EAQ90676.1 - 0.042 13.0 0.1 0.065 12.4 0.1 1.2 1 0 0 1 1 1 0 2-phosphosulpholactate phosphatase NCBP3 PF10309.9 EAQ90677.1 - 1.5e-18 66.3 0.1 3.3e-18 65.3 0.1 1.6 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 Leu_zip PF15294.6 EAQ90678.1 - 0.012 15.1 8.7 0.017 14.7 8.7 1.2 1 0 0 1 1 1 0 Leucine zipper DUF3015 PF11220.8 EAQ90678.1 - 0.039 13.8 0.2 0.29 11.0 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3015) Exonuc_VII_L PF02601.15 EAQ90678.1 - 0.042 13.4 10.0 0.063 12.8 10.0 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Het-C PF07217.11 EAQ90678.1 - 0.063 11.8 1.6 0.088 11.3 1.6 1.1 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C KcnmB2_inactiv PF09303.10 EAQ90678.1 - 0.065 13.0 1.1 0.15 11.8 1.1 1.6 1 0 0 1 1 1 0 KCNMB2, ball and chain domain EMP24_GP25L PF01105.24 EAQ90678.1 - 0.083 12.8 9.5 1.3 9.0 1.1 2.2 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD Serine_rich PF08824.10 EAQ90678.1 - 0.12 12.3 7.2 0.033 14.2 2.7 2.0 1 1 1 2 2 2 0 Serine rich protein interaction domain Tropomyosin_1 PF12718.7 EAQ90678.1 - 0.17 12.0 23.4 24 5.1 23.4 2.2 1 1 0 1 1 1 0 Tropomyosin like Tropomyosin PF00261.20 EAQ90678.1 - 0.2 11.0 21.8 0.63 9.4 5.3 2.1 1 1 1 2 2 2 0 Tropomyosin DUF1664 PF07889.12 EAQ90678.1 - 0.31 11.1 10.0 1.1 9.3 4.2 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) zf-C4H2 PF10146.9 EAQ90678.1 - 0.35 11.1 5.3 0.5 10.6 5.3 1.2 1 0 0 1 1 1 0 Zinc finger-containing protein DUF2408 PF10303.9 EAQ90678.1 - 0.37 11.3 7.7 0.14 12.7 5.1 1.6 2 0 0 2 2 1 0 Protein of unknown function (DUF2408) Imm49 PF15575.6 EAQ90678.1 - 0.41 10.4 6.8 3.6 7.3 5.5 2.5 2 1 0 2 2 2 0 Immunity protein 49 LXG PF04740.12 EAQ90678.1 - 0.85 9.3 9.0 2.5 7.7 9.0 1.8 1 1 0 1 1 1 0 LXG domain of WXG superfamily DUF4279 PF14106.6 EAQ90678.1 - 1.1 9.5 6.6 1.5 9.0 2.2 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4279) OEP PF02321.18 EAQ90678.1 - 1.4 8.7 13.8 1.3 8.8 5.4 2.5 1 1 1 2 2 2 0 Outer membrane efflux protein YkyA PF10368.9 EAQ90678.1 - 3.3 7.3 13.3 6.8 6.3 13.3 1.5 1 1 0 1 1 1 0 Putative cell-wall binding lipoprotein V_ATPase_I PF01496.19 EAQ90678.1 - 3.4 5.5 5.6 4.4 5.1 5.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Kri1 PF05178.12 EAQ90678.1 - 4 8.1 10.1 6.4 7.4 8.3 2.3 1 1 1 2 2 2 0 KRI1-like family Prominin PF05478.11 EAQ90678.1 - 5.6 4.8 6.2 14 3.5 6.2 1.5 1 1 0 1 1 1 0 Prominin Pet127 PF08634.10 EAQ90681.1 - 1.1e-121 405.4 0.7 1.7e-121 404.8 0.7 1.3 1 0 0 1 1 1 1 Mitochondrial protein Pet127 Spore_III_AF PF09581.10 EAQ90681.1 - 8.5 6.4 24.2 3.9 7.5 10.5 3.4 2 1 1 3 3 3 0 Stage III sporulation protein AF (Spore_III_AF) Rhomboid PF01694.22 EAQ90682.1 - 2.9e-31 108.5 9.6 2.9e-31 108.5 9.6 1.8 2 0 0 2 2 2 1 Rhomboid family DUF2594 PF10769.9 EAQ90683.1 - 0.081 13.0 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2594) HNH_2 PF13391.6 EAQ90684.1 - 0.024 14.8 0.0 0.049 13.8 0.0 1.5 1 0 0 1 1 1 0 HNH endonuclease AHH PF14412.6 EAQ90684.1 - 0.13 12.4 0.1 0.47 10.5 0.0 1.9 2 0 0 2 2 2 0 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH Cohesin_load PF10345.9 EAQ90686.1 - 2.2e-166 554.8 5.2 4.1e-109 365.7 4.2 2.4 1 1 1 2 2 2 2 Cohesin loading factor Abhydrolase_1 PF00561.20 EAQ90687.1 - 3.3e-12 46.6 0.9 5.2e-10 39.4 0.4 2.5 2 1 1 3 3 3 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EAQ90687.1 - 3.8e-08 32.9 0.0 1.4e-07 31.1 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 SAM_PNT PF02198.16 EAQ90687.1 - 0.082 12.9 0.0 5.8 7.0 0.0 2.3 2 0 0 2 2 2 0 Sterile alpha motif (SAM)/Pointed domain IGPD PF00475.18 EAQ90689.1 - 5.4e-60 201.9 0.3 8e-60 201.3 0.3 1.3 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase Rep_fac_C PF08542.11 EAQ90691.1 - 1.6e-23 82.9 0.0 4.4e-23 81.5 0.0 1.8 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 EAQ90691.1 - 8.8e-12 45.1 0.0 3.1e-09 36.8 0.1 2.3 1 1 1 2 2 2 2 DNA polymerase III, delta subunit AAA PF00004.29 EAQ90691.1 - 1.5e-11 44.9 0.0 2.9e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 EAQ90691.1 - 2e-06 27.9 0.0 4.2e-06 26.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EAQ90691.1 - 3.2e-06 27.6 0.0 0.00034 21.0 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EAQ90691.1 - 8.8e-05 22.8 0.2 0.14 12.4 0.1 2.6 2 1 1 3 3 2 2 AAA domain RuvB_N PF05496.12 EAQ90691.1 - 0.00024 20.9 0.0 0.00065 19.5 0.0 1.7 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain Viral_helicase1 PF01443.18 EAQ90691.1 - 0.00032 20.5 0.0 0.0005 19.9 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_3 PF07726.11 EAQ90691.1 - 0.00057 19.7 0.0 0.0012 18.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta PF06144.13 EAQ90691.1 - 0.0012 18.7 0.2 0.0019 18.0 0.2 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.15 EAQ90691.1 - 0.0016 18.4 0.0 0.0038 17.2 0.0 1.6 1 1 0 1 1 1 1 Rad17 P-loop domain Mg_chelatase PF01078.21 EAQ90691.1 - 0.0018 17.7 0.0 0.026 13.9 0.0 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI TniB PF05621.11 EAQ90691.1 - 0.005 16.3 0.0 3.2 7.1 0.0 2.5 2 0 0 2 2 2 2 Bacterial TniB protein AAA_assoc_2 PF16193.5 EAQ90691.1 - 0.0073 16.6 0.1 0.024 15.0 0.0 2.0 2 0 0 2 2 1 1 AAA C-terminal domain MeaB PF03308.16 EAQ90691.1 - 0.014 14.4 0.0 0.025 13.6 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DNA_pol3_gamma3 PF12169.8 EAQ90691.1 - 0.018 14.9 0.1 0.43 10.5 0.0 2.6 3 0 0 3 3 2 0 DNA polymerase III subunits gamma and tau domain III AAA_24 PF13479.6 EAQ90691.1 - 0.02 14.7 0.0 0.092 12.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 EAQ90691.1 - 0.027 14.5 0.1 0.14 12.2 0.0 2.3 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.15 EAQ90691.1 - 0.035 14.0 0.2 0.17 11.8 0.1 2.1 1 1 1 2 2 2 0 NTPase AAA_19 PF13245.6 EAQ90691.1 - 0.041 14.2 0.1 0.13 12.6 0.1 2.1 1 1 0 1 1 1 0 AAA domain KTI12 PF08433.10 EAQ90691.1 - 0.042 13.3 0.0 0.073 12.5 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_11 PF13086.6 EAQ90691.1 - 0.056 13.2 0.0 0.097 12.4 0.0 1.3 1 1 0 1 1 1 0 AAA domain DUF5119 PF17145.4 EAQ90691.1 - 0.14 12.1 0.0 0.54 10.2 0.0 1.8 1 1 0 2 2 2 0 Domain of unknown function (DUF5119) DEAD PF00270.29 EAQ90691.1 - 0.14 11.9 0.1 0.97 9.2 0.0 2.1 1 1 1 2 2 2 0 DEAD/DEAH box helicase ArgJ PF01960.18 EAQ90692.1 - 1.4e-153 511.1 0.5 1.6e-153 510.9 0.5 1.0 1 0 0 1 1 1 1 ArgJ family DER1 PF04511.15 EAQ90693.1 - 1e-24 87.5 3.4 1.2e-24 87.3 3.4 1.0 1 0 0 1 1 1 1 Der1-like family TFIIA PF03153.13 EAQ90694.1 - 0.69 9.8 10.0 0.9 9.5 10.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CD99L2 PF12301.8 EAQ90694.1 - 0.99 9.7 0.0 0.99 9.7 0.0 3.4 2 1 1 3 3 3 0 CD99 antigen like protein 2 Methyltransf_23 PF13489.6 EAQ90696.1 - 2.1e-25 89.4 0.0 6.3e-25 87.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAQ90696.1 - 2.2e-05 25.1 0.0 0.038 14.7 0.0 2.4 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 EAQ90696.1 - 0.0037 17.9 0.0 0.02 15.5 0.0 2.0 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAQ90696.1 - 0.0041 16.9 0.0 1.5 8.6 0.0 2.2 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 EAQ90696.1 - 0.033 14.9 0.0 0.11 13.3 0.0 1.8 1 1 1 2 2 2 0 Methyltransferase domain DUF1127 PF06568.11 EAQ90698.1 - 0.17 11.6 0.2 0.31 10.8 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1127) Tuberculin PF12198.8 EAQ90699.1 - 0.02 15.0 0.4 0.053 13.6 0.4 1.8 1 0 0 1 1 1 0 Theoretical tuberculin protein CN_hydrolase PF00795.22 EAQ90700.1 - 8.8e-13 48.2 0.0 2.1e-12 47.0 0.0 1.6 2 0 0 2 2 2 1 Carbon-nitrogen hydrolase DKCLD PF08068.12 EAQ90702.1 - 6.9e-33 112.5 0.6 1.3e-31 108.5 0.5 2.4 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.18 EAQ90702.1 - 3.1e-23 82.8 0.2 4.3e-20 72.6 0.2 3.4 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 EAQ90702.1 - 7.3e-22 77.3 0.2 1.4e-21 76.4 0.2 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain PUA PF01472.20 EAQ90702.1 - 1.7e-21 76.0 0.9 3.7e-21 74.9 0.9 1.7 1 0 0 1 1 1 1 PUA domain UPF0113 PF03657.13 EAQ90702.1 - 0.00065 19.9 0.0 0.0017 18.6 0.0 1.7 1 0 0 1 1 1 1 UPF0113 PUA domain RNA_polI_A34 PF08208.11 EAQ90702.1 - 2.9 7.9 23.0 4.6 7.3 23.0 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 SAC3_GANP PF03399.16 EAQ90704.1 - 2.2e-94 316.1 0.3 3.3e-94 315.6 0.3 1.2 1 0 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 EAQ90704.1 - 0.001 19.1 0.0 0.0022 18.0 0.0 1.5 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family Methyltransf_25 PF13649.6 EAQ90705.1 - 2.7e-07 31.2 0.0 5.4e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EAQ90705.1 - 2.6e-06 28.0 0.0 5.6e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EAQ90705.1 - 5.2e-06 27.1 0.0 1.3e-05 25.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EAQ90705.1 - 5.1e-05 23.2 0.0 7.5e-05 22.6 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 EAQ90705.1 - 0.0098 15.8 0.0 0.015 15.1 0.0 1.5 1 0 0 1 1 1 1 Hypothetical methyltransferase Ubie_methyltran PF01209.18 EAQ90705.1 - 0.014 14.8 0.0 0.066 12.5 0.0 1.9 1 1 1 2 2 2 0 ubiE/COQ5 methyltransferase family CN_hydrolase PF00795.22 EAQ90706.1 - 1.2e-41 142.8 0.0 1.6e-41 142.4 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 EAQ90706.1 - 1.1e-14 54.2 0.0 4.5e-10 39.1 0.0 2.7 1 1 1 2 2 2 2 NAD synthase Polyketide_cyc PF03364.20 EAQ90707.1 - 9.8e-19 67.8 0.8 1.4e-14 54.4 0.1 2.3 1 1 1 2 2 2 2 Polyketide cyclase / dehydrase and lipid transport TPR_19 PF14559.6 EAQ90710.1 - 2.8e-09 37.4 2.5 3.3e-05 24.3 0.1 3.6 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EAQ90710.1 - 4.1e-09 35.9 2.3 0.00014 21.7 0.1 4.9 6 0 0 6 6 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 EAQ90710.1 - 3e-07 30.0 2.0 0.0018 17.9 0.0 4.4 5 1 1 6 6 6 3 TPR repeat TPR_16 PF13432.6 EAQ90710.1 - 1.6e-05 25.5 0.6 1.6e-05 25.5 0.6 3.8 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 EAQ90710.1 - 0.00037 21.1 10.2 0.18 12.7 0.2 5.2 4 2 1 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 EAQ90710.1 - 0.0011 19.3 3.5 0.41 11.0 0.1 4.2 2 1 1 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 EAQ90710.1 - 0.02 15.3 0.0 0.11 13.0 0.0 2.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_9 PF13371.6 EAQ90710.1 - 0.021 15.0 3.0 0.22 11.7 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 EAQ90710.1 - 0.021 15.4 1.5 29 5.6 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat Wzy_C_2 PF11846.8 EAQ90710.1 - 0.034 14.1 0.0 0.082 12.8 0.0 1.6 1 0 0 1 1 1 0 Virulence factor membrane-bound polymerase, C-terminal TPR_1 PF00515.28 EAQ90710.1 - 0.037 13.9 0.1 0.59 10.0 0.1 3.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Phycobilisome PF00502.19 EAQ90710.1 - 0.052 13.5 0.1 0.14 12.1 0.0 1.7 2 0 0 2 2 2 0 Phycobilisome protein TPR_20 PF14561.6 EAQ90710.1 - 0.073 13.4 3.3 5.9 7.3 0.0 3.6 2 1 1 4 4 4 0 Tetratricopeptide repeat TAF1_subA PF14929.6 EAQ90710.1 - 0.076 12.4 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 TAF RNA Polymerase I subunit A TPR_7 PF13176.6 EAQ90710.1 - 0.18 11.9 0.8 15 5.9 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Adaptin_N PF01602.20 EAQ90711.1 - 8.4e-77 258.9 0.0 1.4e-76 258.1 0.0 1.3 1 1 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EAQ90711.1 - 0.047 13.7 0.0 0.27 11.3 0.0 2.1 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 TGT PF01702.18 EAQ90712.1 - 1.2e-63 215.5 0.0 1.5e-63 215.1 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase LCCL PF03815.19 EAQ90713.1 - 5e-11 42.6 0.3 7.9e-11 41.9 0.3 1.3 1 0 0 1 1 1 1 LCCL domain DUF3391 PF11871.8 EAQ90714.1 - 0.1 13.1 0.6 0.22 12.1 0.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) Pes-10 PF07149.11 EAQ90714.1 - 0.26 10.3 4.3 0.32 10.0 4.3 1.2 1 0 0 1 1 1 0 Pes-10 Filament PF00038.21 EAQ90715.1 - 8e-05 22.4 9.1 8e-05 22.4 9.1 5.0 2 1 3 5 5 5 2 Intermediate filament protein CEP63 PF17045.5 EAQ90715.1 - 0.00035 20.6 9.3 0.00035 20.6 9.3 3.7 3 1 0 4 4 4 1 Centrosomal protein of 63 kDa ATG16 PF08614.11 EAQ90715.1 - 0.0021 18.3 5.0 0.0021 18.3 5.0 5.6 3 1 2 5 5 5 2 Autophagy protein 16 (ATG16) COG5 PF10392.9 EAQ90715.1 - 0.32 11.2 10.9 0.03 14.5 3.9 2.8 2 1 0 2 2 2 0 Golgi transport complex subunit 5 DUF4407 PF14362.6 EAQ90715.1 - 0.48 9.7 50.0 0.008 15.6 13.1 3.4 3 1 1 4 4 4 0 Domain of unknown function (DUF4407) Piezo_RRas_bdg PF12166.8 EAQ90715.1 - 0.65 9.2 1.5 0.98 8.6 1.5 1.2 1 0 0 1 1 1 0 Piezo non-specific cation channel, R-Ras-binding domain TSC22 PF01166.18 EAQ90715.1 - 3.6 8.0 16.1 13 6.2 0.3 5.3 5 1 1 6 6 6 0 TSC-22/dip/bun family DUF3658 PF12395.8 EAQ90715.1 - 3.7 7.5 9.3 1.3 9.0 0.1 3.6 3 0 0 3 3 3 0 Protein of unknown function Peptidase_S46 PF10459.9 EAQ90715.1 - 3.9 6.0 20.0 6.8 5.2 20.0 1.3 1 0 0 1 1 1 0 Peptidase S46 MCC-bdg_PDZ PF10506.9 EAQ90715.1 - 4.2 7.5 20.5 0.16 12.0 0.7 5.2 4 1 1 5 5 5 0 PDZ domain of MCC-2 bdg protein for Usher syndrome FlaC_arch PF05377.11 EAQ90715.1 - 6.2 7.3 31.3 0.12 12.7 1.0 7.1 8 0 0 8 8 8 0 Flagella accessory protein C (FlaC) DUF4763 PF15960.5 EAQ90715.1 - 6.6 6.0 16.5 0.46 9.8 10.1 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4763) Transketolase_N PF00456.21 EAQ90716.1 - 1.2e-153 511.0 0.1 1.6e-153 510.5 0.1 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 EAQ90716.1 - 3.4e-44 150.6 0.0 5.6e-44 149.9 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EAQ90716.1 - 2.4e-13 50.0 0.0 5.3e-13 48.9 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 EAQ90716.1 - 0.00035 19.9 0.0 0.00054 19.3 0.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 EAQ90716.1 - 0.0017 18.1 2.1 0.02 14.7 0.7 3.1 3 1 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Methyltransf_34 PF11312.8 EAQ90717.1 - 2.4e-112 375.1 0.0 4.5e-112 374.3 0.0 1.4 2 0 0 2 2 2 1 Putative SAM-dependent methyltransferase Syja_N PF02383.18 EAQ90718.1 - 1.5e-92 310.3 0.0 2.2e-92 309.8 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.8 EAQ90718.1 - 7e-42 141.8 0.0 1.2e-41 141.0 0.0 1.4 1 0 0 1 1 1 1 Inositol phosphatase ATP-synt_C PF00137.21 EAQ90719.1 - 1.7e-34 117.9 35.7 9.9e-22 77.1 16.1 2.1 2 0 0 2 2 2 2 ATP synthase subunit C CiPC PF15800.5 EAQ90720.1 - 0.0051 16.6 19.0 0.0061 16.3 19.0 1.0 1 0 0 1 1 1 1 Clock interacting protein circadian GREB1 PF15782.5 EAQ90720.1 - 0.45 7.6 27.7 0.53 7.4 27.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Fibrinogen_BP PF08017.11 EAQ90720.1 - 0.53 8.7 20.3 0.65 8.4 20.3 1.0 1 0 0 1 1 1 0 Fibrinogen binding protein DUF966 PF06136.13 EAQ90720.1 - 0.64 9.7 18.8 0.73 9.5 18.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Presenilin PF01080.17 EAQ90720.1 - 2.3 6.9 27.8 2.9 6.6 27.8 1.1 1 0 0 1 1 1 0 Presenilin DUF4045 PF13254.6 EAQ90720.1 - 2.3 7.8 23.9 2.7 7.5 23.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) TFIIA PF03153.13 EAQ90720.1 - 2.7 7.9 55.8 3.3 7.6 55.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2807 PF10988.8 EAQ90720.1 - 5.7 6.7 14.9 39 4.0 14.9 2.1 1 1 0 1 1 1 0 Putative auto-transporter adhesin, head GIN domain ERG4_ERG24 PF01222.17 EAQ90721.1 - 5.8e-102 341.6 18.5 7.9e-55 186.3 7.9 2.9 1 1 1 2 2 2 2 Ergosterol biosynthesis ERG4/ERG24 family Ank_2 PF12796.7 EAQ90721.1 - 7.8e-23 80.9 0.4 1.6e-11 44.6 0.0 3.8 2 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAQ90721.1 - 6.8e-18 64.8 3.6 1.5e-08 35.0 0.0 4.6 4 1 0 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAQ90721.1 - 7.4e-16 56.7 7.3 0.016 15.7 0.0 7.1 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.6 EAQ90721.1 - 5.8e-13 48.8 13.3 0.00012 22.3 0.3 5.3 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 EAQ90721.1 - 8.3e-09 35.5 6.2 0.055 13.9 0.0 5.9 5 0 0 5 5 5 3 Ankyrin repeat L_HMGIC_fpl PF10242.9 EAQ90722.1 - 0.00018 21.8 0.1 0.00036 20.8 0.1 1.4 1 0 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein Pkinase PF00069.25 EAQ90723.1 - 2e-48 165.0 0.0 1.1e-41 143.0 0.0 2.5 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ90723.1 - 1.2e-30 106.7 0.0 5.5e-28 98.0 0.0 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 EAQ90723.1 - 0.00012 21.0 0.0 0.0002 20.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EAQ90723.1 - 0.011 15.1 0.0 0.027 13.8 0.1 1.6 1 1 1 2 2 2 0 Kinase-like DUF3446 PF11928.8 EAQ90724.1 - 9.5 6.6 9.8 19 5.6 5.6 2.5 2 0 0 2 2 2 0 Early growth response N-terminal domain Mur_ligase_M PF08245.12 EAQ90725.1 - 1.6e-06 28.2 0.1 3.4e-06 27.2 0.0 1.6 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 EAQ90725.1 - 0.024 14.9 0.0 0.045 14.0 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain Shisa PF13908.6 EAQ90726.1 - 0.0054 17.0 3.2 0.0062 16.8 3.2 1.1 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Orf78 PF06024.12 EAQ90726.1 - 0.02 15.2 1.1 0.027 14.8 1.1 1.2 1 0 0 1 1 1 0 Orf78 (ac78) DUF4577 PF15145.6 EAQ90726.1 - 0.028 14.5 0.2 0.043 13.9 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4577) FA_desaturase PF00487.24 EAQ90726.1 - 0.049 13.5 1.3 0.065 13.1 1.3 1.1 1 0 0 1 1 1 0 Fatty acid desaturase Anoctamin PF04547.12 EAQ90726.1 - 0.12 11.2 0.8 0.14 11.0 0.8 1.1 1 0 0 1 1 1 0 Calcium-activated chloride channel OSTMP1 PF09777.9 EAQ90726.1 - 0.3 10.4 3.5 0.57 9.5 3.5 1.5 1 1 0 1 1 1 0 Osteopetrosis-associated transmembrane protein 1 precursor Amnionless PF14828.6 EAQ90726.1 - 0.52 9.1 2.5 0.59 8.9 2.5 1.1 1 0 0 1 1 1 0 Amnionless DUF3040 PF11239.8 EAQ90726.1 - 0.74 10.1 10.3 1.3 9.3 10.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) TMEM154 PF15102.6 EAQ90726.1 - 0.74 9.7 4.7 1.1 9.1 4.7 1.3 1 0 0 1 1 1 0 TMEM154 protein family HemY_N PF07219.13 EAQ90726.1 - 1.1 9.5 10.3 0.6 10.3 8.2 1.6 2 0 0 2 2 2 0 HemY protein N-terminus EVI2A PF05399.11 EAQ90726.1 - 2.3 7.8 3.8 2.8 7.5 3.8 1.1 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) DUF4231 PF14015.6 EAQ90726.1 - 3 8.4 5.7 5.2 7.6 5.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4231) Protocadherin PF08374.11 EAQ90726.1 - 8.6 6.3 6.9 12 5.8 6.9 1.2 1 0 0 1 1 1 0 Protocadherin DUF2749 PF10907.8 EAQ90726.1 - 8.6 6.6 9.0 16 5.8 9.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2749) SCA7 PF08313.12 EAQ90728.1 - 6.6e-30 102.8 0.1 2.1e-29 101.2 0.0 1.7 1 1 1 2 2 2 1 SCA7, zinc-binding domain DUF3176 PF11374.8 EAQ90729.1 - 4.9e-27 94.2 0.8 4.9e-27 94.2 0.8 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) zf-C2H2 PF00096.26 EAQ90731.1 - 0.00017 21.8 16.9 0.0057 17.0 2.8 3.8 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EAQ90731.1 - 0.0095 16.7 13.3 0.76 10.8 2.2 4.1 4 0 0 4 4 4 2 C2H2-type zinc finger DUF3450 PF11932.8 EAQ90731.1 - 0.03 13.6 3.6 0.05 12.9 3.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) RNA_pol_Rpb1_1 PF04997.12 EAQ90731.1 - 0.11 11.8 1.0 0.17 11.2 1.0 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 1 zf-C2H2_aberr PF17017.5 EAQ90731.1 - 0.14 12.3 0.1 0.34 11.0 0.1 1.7 1 1 0 1 1 1 0 Aberrant zinc-finger GBP_C PF02841.14 EAQ90731.1 - 0.25 10.7 5.8 0.36 10.2 5.8 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain UPF0242 PF06785.11 EAQ90731.1 - 0.37 10.9 3.3 0.62 10.1 3.3 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus zf-H2C2_2 PF13465.6 EAQ90731.1 - 0.65 10.5 13.8 13 6.4 0.2 3.7 3 0 0 3 3 3 0 Zinc-finger double domain zf-H2C2_5 PF13909.6 EAQ90731.1 - 7.7 6.4 9.2 0.4 10.5 0.9 3.0 3 0 0 3 3 3 0 C2H2-type zinc-finger domain PALP PF00291.25 EAQ90732.1 - 4.3e-31 108.4 0.8 3.2e-23 82.6 0.3 2.0 1 1 1 2 2 2 2 Pyridoxal-phosphate dependent enzyme MFS_1 PF07690.16 EAQ90733.1 - 4.8e-32 111.3 33.2 4.8e-32 111.3 33.2 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EAQ90733.1 - 3.9e-05 22.7 14.8 6.4e-05 22.0 14.8 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter UNC-93 PF05978.16 EAQ90733.1 - 0.17 11.6 7.7 0.018 14.8 2.5 2.1 2 0 0 2 2 2 0 Ion channel regulatory protein UNC-93 PQ-loop PF04193.14 EAQ90737.1 - 7.6e-29 99.3 21.9 7.3e-16 57.7 3.6 2.7 3 0 0 3 3 3 2 PQ loop repeat Mito_carr PF00153.27 EAQ90739.1 - 2e-72 239.2 0.3 2.5e-26 91.4 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.32 EAQ90739.1 - 1.2e-15 55.8 0.3 1.7e-06 27.2 0.0 5.1 5 0 0 5 5 5 3 EF hand EF-hand_7 PF13499.6 EAQ90739.1 - 8.7e-15 54.9 2.5 1e-07 32.3 0.1 3.1 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EAQ90739.1 - 8.8e-14 50.2 2.0 2.9e-05 23.6 0.0 5.4 5 0 0 5 5 5 3 EF-hand domain EF-hand_5 PF13202.6 EAQ90739.1 - 1.4e-11 43.3 0.4 4e-07 29.2 0.1 4.2 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 EAQ90739.1 - 4.8e-09 35.9 0.9 0.016 15.0 0.0 4.8 5 0 0 5 5 5 3 EF-hand domain pair EF-hand_10 PF14788.6 EAQ90739.1 - 0.048 13.5 0.4 5.1 7.0 0.1 3.4 3 1 0 3 3 3 0 EF hand Cyclin_N PF00134.23 EAQ90740.1 - 1.1e-43 148.0 0.3 2.1e-43 147.1 0.3 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EAQ90740.1 - 6.8e-35 119.7 0.0 2.1e-34 118.1 0.0 1.9 2 0 0 2 2 2 1 Cyclin, C-terminal domain Zn_clus PF00172.18 EAQ90742.1 - 0.0024 17.9 12.3 0.0042 17.2 12.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_3 PF01494.19 EAQ90744.1 - 4.1e-14 52.6 0.0 3e-06 26.7 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 EAQ90744.1 - 9.6e-11 41.8 2.3 5e-06 26.3 0.1 2.1 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EAQ90744.1 - 1.1e-05 24.8 0.1 9.2e-05 21.8 0.1 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EAQ90744.1 - 2.4e-05 23.3 0.4 0.013 14.2 0.1 2.2 2 0 0 2 2 2 2 HI0933-like protein Lycopene_cycl PF05834.12 EAQ90744.1 - 0.0001 21.5 0.4 0.046 12.8 0.4 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein FAD_binding_2 PF00890.24 EAQ90744.1 - 0.00039 19.6 1.0 0.00065 18.9 1.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 EAQ90744.1 - 0.001 19.6 0.2 1.1 9.8 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EAQ90744.1 - 0.0016 18.6 0.1 0.005 17.0 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 EAQ90744.1 - 0.0033 16.8 0.3 0.74 9.0 0.0 2.6 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase GIDA PF01134.22 EAQ90744.1 - 0.14 11.2 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Thi4 PF01946.17 EAQ90744.1 - 0.17 11.1 0.1 0.33 10.2 0.1 1.4 1 0 0 1 1 1 0 Thi4 family RNA_pol_Rpc4 PF05132.14 EAQ90745.1 - 6.3e-27 94.8 0.0 6.3e-27 94.8 0.0 3.4 3 2 0 3 3 3 1 RNA polymerase III RPC4 DUF2397 PF09660.10 EAQ90745.1 - 0.61 8.9 4.6 1.1 8.1 4.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2397) UreD PF01774.17 EAQ90746.1 - 1.6e-75 253.7 2.7 6e-74 248.5 0.1 2.7 3 0 0 3 3 3 1 UreD urease accessory protein STAG PF08514.11 EAQ90746.1 - 1.1e-38 131.6 2.5 4.1e-38 129.8 0.8 2.9 2 0 0 2 2 2 1 STAG domain Leu_zip PF15294.6 EAQ90746.1 - 0.037 13.5 0.9 1.4 8.4 0.3 2.6 2 0 0 2 2 2 0 Leucine zipper Cnd1 PF12717.7 EAQ90746.1 - 0.13 12.3 0.1 20 5.2 0.0 3.0 2 1 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 DUF1664 PF07889.12 EAQ90746.1 - 0.3 11.1 1.5 9.9 6.2 0.9 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) TSNAXIP1_N PF15739.5 EAQ90746.1 - 0.46 10.9 4.0 0.19 12.1 0.1 2.3 2 1 1 3 3 3 0 Translin-associated factor X-interacting N-terminus Fib_alpha PF08702.10 EAQ90746.1 - 0.49 10.6 2.8 2 8.6 0.9 2.5 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family POT1PC PF16686.5 EAQ90747.1 - 1.3e-39 135.5 0.0 2.6e-39 134.6 0.0 1.5 1 0 0 1 1 1 1 ssDNA-binding domain of telomere protection protein POT1 PF02765.17 EAQ90747.1 - 2.3e-26 92.4 0.0 4.6e-26 91.4 0.0 1.6 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 tRNA_anti-codon PF01336.25 EAQ90747.1 - 4.2e-06 26.7 0.0 0.0015 18.5 0.0 3.0 2 1 1 3 3 3 2 OB-fold nucleic acid binding domain Arm PF00514.23 EAQ90748.1 - 9.4e-97 314.5 16.0 9.5e-14 50.9 0.2 8.4 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat IBB PF01749.20 EAQ90748.1 - 2.2e-27 95.3 2.1 2.5e-27 95.2 0.5 2.0 2 0 0 2 2 1 1 Importin beta binding domain HEAT_EZ PF13513.6 EAQ90748.1 - 5.8e-25 87.4 6.4 8.6e-10 38.9 0.1 6.4 5 1 1 6 6 6 4 HEAT-like repeat Arm_3 PF16186.5 EAQ90748.1 - 2.7e-23 81.3 5.6 4.2e-23 80.7 4.4 1.9 2 0 0 2 2 2 1 Atypical Arm repeat HEAT_2 PF13646.6 EAQ90748.1 - 4.7e-20 71.8 0.1 4.9e-09 36.5 0.0 5.2 2 2 1 4 4 4 3 HEAT repeats HEAT PF02985.22 EAQ90748.1 - 1.9e-19 68.0 3.8 2.1e-06 27.5 0.0 7.3 8 0 0 8 8 8 4 HEAT repeat Arm_2 PF04826.13 EAQ90748.1 - 2.1e-08 34.0 0.0 0.067 12.6 0.0 4.0 2 1 2 4 4 4 3 Armadillo-like Adaptin_N PF01602.20 EAQ90748.1 - 8.5e-06 24.6 0.0 0.00047 18.9 0.0 2.3 1 1 1 2 2 2 1 Adaptin N terminal region V-ATPase_H_C PF11698.8 EAQ90748.1 - 4.5e-05 23.5 0.0 1.7 8.7 0.0 4.4 3 2 2 5 5 5 2 V-ATPase subunit H HEAT_PBS PF03130.16 EAQ90748.1 - 0.00042 20.7 0.6 0.56 11.0 0.1 4.3 4 0 0 4 4 4 1 PBS lyase HEAT-like repeat NopRA1 PF16201.5 EAQ90748.1 - 0.00088 18.9 0.0 0.3 10.6 0.0 3.9 2 2 1 4 4 4 1 Nucleolar pre-ribosomal-associated protein 1 Cnd1 PF12717.7 EAQ90748.1 - 0.0012 18.9 0.0 1.7 8.7 0.0 2.8 2 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 RICTOR_V PF14668.6 EAQ90748.1 - 0.0057 16.9 3.0 0.9 9.8 0.0 4.5 3 2 2 6 6 6 1 Rapamycin-insensitive companion of mTOR, domain 5 Glycos_trans_3N PF02885.17 EAQ90748.1 - 0.069 13.0 0.0 7.1 6.6 0.0 3.2 3 0 0 3 3 3 0 Glycosyl transferase family, helical bundle domain HA2 PF04408.23 EAQ90749.1 - 6e-18 65.1 0.8 5.8e-17 61.9 0.0 2.6 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EAQ90749.1 - 2.4e-15 56.8 0.0 5.2e-15 55.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 EAQ90749.1 - 1.2e-14 54.4 0.1 3.8e-14 52.8 0.0 1.9 2 0 0 2 2 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 EAQ90749.1 - 4.7e-11 42.8 0.1 8.4e-11 42.0 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAQ90749.1 - 0.0026 18.0 0.8 0.015 15.6 0.8 2.2 1 1 0 1 1 1 1 AAA domain RWD PF05773.22 EAQ90749.1 - 0.0095 16.2 0.0 0.033 14.5 0.0 1.9 2 0 0 2 2 2 1 RWD domain ATPase PF06745.13 EAQ90749.1 - 0.016 14.5 0.1 0.033 13.5 0.1 1.4 1 0 0 1 1 1 0 KaiC AAA_29 PF13555.6 EAQ90749.1 - 0.017 14.8 0.0 0.039 13.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain IHABP4_N PF16174.5 EAQ90749.1 - 0.024 15.3 0.6 0.024 15.3 0.6 2.5 3 0 0 3 3 2 0 Intracellular hyaluronan-binding protein 4 N-terminal DND1_DSRM PF14709.7 EAQ90749.1 - 0.04 14.2 0.0 0.15 12.4 0.0 2.0 1 0 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 T2SSE PF00437.20 EAQ90749.1 - 0.042 12.9 0.0 0.079 12.0 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein RsgA_GTPase PF03193.16 EAQ90749.1 - 0.15 11.9 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_23 PF13476.6 EAQ90749.1 - 0.31 11.5 0.1 0.31 11.5 0.1 1.8 2 0 0 2 2 1 0 AAA domain AT_hook PF02178.19 EAQ90750.1 - 0.36 10.8 54.2 0.13 12.2 4.2 5.5 5 0 0 5 5 5 0 AT hook motif ICE2 PF08426.10 EAQ90751.1 - 3.6e-112 375.4 6.8 1.1e-57 196.1 5.6 2.0 1 1 1 2 2 2 2 ICE2 MTTB PF06253.11 EAQ90753.1 - 0.016 13.2 0.0 0.021 12.8 0.0 1.1 1 0 0 1 1 1 0 Trimethylamine methyltransferase (MTTB) Snf7 PF03357.21 EAQ90754.1 - 2.1e-33 115.4 16.9 2.1e-33 115.4 16.9 2.0 1 1 1 2 2 2 1 Snf7 DUF3502 PF12010.8 EAQ90754.1 - 0.011 16.4 0.5 0.021 15.4 0.5 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3502) Fmp27_WPPW PF10359.9 EAQ90754.1 - 0.027 13.3 8.3 0.032 13.1 8.3 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Misat_Tub_SegII PF10644.9 EAQ90754.1 - 0.15 12.4 4.4 0.13 12.6 2.3 2.0 1 1 1 2 2 2 0 Misato Segment II tubulin-like domain DUF3138 PF11336.8 EAQ90754.1 - 0.27 9.8 3.7 0.062 11.9 1.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) Phage_TAC_5 PF08890.11 EAQ90754.1 - 0.3 11.1 6.7 5.4 7.0 0.1 2.3 1 1 1 2 2 2 0 Phage XkdN-like tail assembly chaperone protein, TAC V-ATPase_G_2 PF16999.5 EAQ90754.1 - 0.43 11.0 11.1 0.06 13.8 6.5 2.0 2 0 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit Translin PF01997.16 EAQ90756.1 - 5.1e-38 131.1 0.2 2.3e-36 125.7 0.2 2.0 1 1 0 1 1 1 1 Translin family DUF4686 PF15742.5 EAQ90756.1 - 0.016 14.4 0.3 0.024 13.8 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4686) Raco_middle PF17651.1 EAQ90756.1 - 0.02 14.6 0.0 0.032 13.9 0.0 1.4 1 0 0 1 1 1 0 RACo middle region DCX PF03607.17 EAQ90756.1 - 0.025 14.7 0.1 0.06 13.5 0.1 1.6 1 0 0 1 1 1 0 Doublecortin PIG-F PF06699.11 EAQ90757.1 - 2.3e-65 220.2 2.0 2.8e-65 219.9 2.0 1.1 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F Ribosomal_L22e PF01776.17 EAQ90758.1 - 6.6e-45 152.0 1.6 8e-45 151.7 1.6 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family Pmp3 PF01679.17 EAQ90759.1 - 2.5e-15 56.4 3.3 2.9e-15 56.2 3.3 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator RVT_1 PF00078.27 EAQ90760.1 - 1.7e-29 102.9 0.0 1.3e-21 77.2 0.0 2.3 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 EAQ90760.1 - 0.00073 19.4 0.0 0.0032 17.3 0.0 2.0 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 EAQ90760.1 - 0.015 14.8 0.0 0.032 13.8 0.0 1.6 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family Myb_DNA-bind_3 PF12776.7 EAQ90761.1 - 5e-07 30.6 0.0 9.6e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain LZ_Tnp_IS66 PF13007.7 EAQ90761.1 - 0.45 11.3 3.0 6.9 7.5 0.4 2.9 2 0 0 2 2 2 0 Transposase C of IS166 homeodomain MULE PF10551.9 EAQ90762.1 - 2.8e-28 98.1 0.0 5.5e-28 97.2 0.0 1.5 1 0 0 1 1 1 1 MULE transposase domain MULE PF10551.9 EAQ90763.1 - 9.2e-26 90.1 0.1 3.6e-25 88.2 0.1 2.1 1 0 0 1 1 1 1 MULE transposase domain HTH_Tnp_Tc3_2 PF01498.18 EAQ90763.1 - 1.5e-14 54.0 2.3 1.5e-14 54.0 2.3 1.8 2 0 0 2 2 1 1 Transposase DDE_3 PF13358.6 EAQ90763.1 - 3e-12 46.5 0.2 7.3e-12 45.3 0.2 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.6 EAQ90763.1 - 2.9e-06 27.2 1.8 2.5e-05 24.2 0.4 2.6 2 0 0 2 2 2 1 Winged helix-turn helix HTH_32 PF13565.6 EAQ90763.1 - 8.1e-06 26.4 3.0 1.2e-05 25.9 0.8 2.6 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 EAQ90763.1 - 0.014 15.5 2.4 0.022 14.9 0.2 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_23 PF13384.6 EAQ90763.1 - 0.044 13.6 0.5 0.044 13.6 0.5 2.4 2 0 0 2 2 2 0 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.6 EAQ90763.1 - 0.075 12.5 0.3 0.075 12.5 0.3 3.5 4 0 0 4 4 4 0 Helix-turn-helix domain of transposase family ISL3 HTH_7 PF02796.15 EAQ90763.1 - 0.09 12.9 0.0 0.52 10.4 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase XkdW PF09636.10 EAQ90763.1 - 0.11 12.6 0.8 0.28 11.3 0.2 2.0 2 0 0 2 2 2 0 XkdW protein HTH_38 PF13936.6 EAQ90763.1 - 0.12 12.1 0.0 0.12 12.1 0.0 2.4 3 0 0 3 3 3 0 Helix-turn-helix domain TALPID3 PF15324.6 EAQ90764.1 - 0.16 9.6 0.3 0.21 9.2 0.3 1.1 1 0 0 1 1 1 0 Hedgehog signalling target Helicase_C PF00271.31 EAQ90766.1 - 2.3e-09 37.6 0.1 5e-09 36.5 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EAQ90766.1 - 0.00018 21.6 0.0 0.00029 20.9 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAQ90766.1 - 0.002 17.9 0.0 0.0051 16.6 0.0 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase DDE_1 PF03184.19 EAQ90768.1 - 1.5e-26 93.1 0.0 3.2e-26 92.1 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.16 EAQ90768.1 - 1.7e-10 40.5 0.0 3.3e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.16 EAQ90768.1 - 0.00013 21.9 0.0 0.00038 20.4 0.0 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain SpoIIID PF12116.8 EAQ90768.1 - 0.024 14.7 0.0 0.077 13.1 0.0 1.8 1 0 0 1 1 1 0 Stage III sporulation protein D zf-RVT PF13966.6 EAQ90770.1 - 0.01 16.5 0.0 0.016 15.9 0.0 1.3 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase DDE_1 PF03184.19 EAQ90771.1 - 6.5e-13 48.7 0.0 2.1e-12 47.1 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease DDE_3 PF13358.6 EAQ90771.1 - 0.00038 20.2 0.1 0.001 18.9 0.1 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease zf-CCHC_2 PF13696.6 EAQ90771.1 - 0.17 11.8 1.1 0.49 10.3 1.1 1.8 1 0 0 1 1 1 0 Zinc knuckle RT_RNaseH PF17917.1 EAQ90772.1 - 7.6e-32 109.7 0.0 1.9e-31 108.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 EAQ90772.1 - 3.7e-31 107.1 0.0 8.1e-31 106.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 EAQ90772.1 - 1.1e-26 93.8 0.0 9.8e-26 90.6 0.0 2.4 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 EAQ90772.1 - 2.8e-14 52.9 0.0 6.4e-14 51.8 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 EAQ90772.1 - 5.1e-13 49.3 0.0 1.7e-12 47.6 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 EAQ90772.1 - 8.4e-06 25.6 0.7 3.1e-05 23.8 0.3 2.2 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain zf-CCHC PF00098.23 EAQ90772.1 - 7.8e-05 22.6 2.5 0.00025 21.0 2.5 1.9 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 EAQ90772.1 - 0.0068 16.1 2.0 0.019 14.7 2.0 1.8 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger Retrotrans_gag PF03732.17 EAQ90772.1 - 0.034 14.4 0.1 0.034 14.4 0.1 3.6 3 0 0 3 3 3 0 Retrotransposon gag protein DUF1257 PF06868.11 EAQ90772.1 - 0.057 13.7 3.3 0.68 10.2 0.2 3.2 2 1 1 3 3 2 0 Protein of unknown function (DUF1257) YabA PF06156.13 EAQ90772.1 - 0.069 13.8 4.6 0.25 12.0 3.6 2.4 2 0 0 2 2 2 0 Initiation control protein YabA MLVIN_C PF18697.1 EAQ90772.1 - 0.1 12.7 0.0 0.36 10.9 0.0 2.0 1 0 0 1 1 1 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain DUF5387 PF17361.2 EAQ90772.1 - 0.12 12.0 1.7 2.3 7.8 0.0 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5387) bZIP_1 PF00170.21 EAQ90772.1 - 0.43 10.7 2.9 4.3 7.5 0.1 2.7 1 1 1 2 2 2 0 bZIP transcription factor ZapB PF06005.12 EAQ90772.1 - 0.47 10.9 4.6 2.8 8.5 4.6 2.4 1 0 0 1 1 1 0 Cell division protein ZapB SlyX PF04102.12 EAQ90772.1 - 4.5 8.0 7.4 30 5.3 3.9 3.7 3 1 0 3 3 2 0 SlyX TPR_MLP1_2 PF07926.12 EAQ90772.1 - 5.2 7.1 8.7 5.2 7.1 0.1 2.8 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein RVT_1 PF00078.27 EAQ90773.1 - 2.4e-48 164.6 0.0 2.2e-47 161.4 0.0 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RecC_C PF17946.1 EAQ90773.1 - 0.56 10.0 5.2 0.24 11.2 0.6 2.3 2 0 0 2 2 2 0 RecC C-terminal domain Pan_kinase PF03309.14 EAQ90774.1 - 0.19 11.6 0.0 0.33 10.8 0.0 1.3 1 0 0 1 1 1 0 Type III pantothenate kinase PIF1 PF05970.14 EAQ90775.1 - 5e-26 91.7 0.0 7.5e-26 91.1 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase Helitron_like_N PF14214.6 EAQ90775.1 - 3e-21 76.5 1.3 1.6e-19 70.8 0.1 2.3 1 1 1 2 2 2 2 Helitron helicase-like domain at N-terminus AAA_30 PF13604.6 EAQ90775.1 - 4.6e-12 46.0 0.0 2.7e-11 43.6 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EAQ90775.1 - 9.8e-06 26.0 0.0 2e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain Herpes_Helicase PF02689.14 EAQ90775.1 - 0.00012 20.2 0.0 0.0052 14.8 0.0 2.1 2 0 0 2 2 2 2 Helicase UvrD_C_2 PF13538.6 EAQ90775.1 - 0.004 17.0 0.1 0.013 15.4 0.0 1.9 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain Torsin PF06309.11 EAQ90775.1 - 0.091 12.9 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Torsin AT_hook PF02178.19 EAQ90775.1 - 4.7 7.4 6.2 3.5 7.8 1.0 3.1 2 0 0 2 2 2 0 AT hook motif UCH PF00443.29 EAQ90776.1 - 1.5e-36 126.3 0.0 1.3e-31 110.0 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EAQ90776.1 - 0.00014 21.6 0.0 0.33 10.5 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Oxysterol_BP PF01237.18 EAQ90777.1 - 1e-60 205.6 0.4 3e-58 197.5 0.4 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein GFO_IDH_MocA PF01408.22 EAQ90778.1 - 7.9e-13 49.3 0.0 2.4e-12 47.7 0.0 1.8 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EAQ90778.1 - 2.7e-05 24.2 0.0 5.6e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain ImpA_N PF06812.12 EAQ90778.1 - 0.17 12.0 0.0 0.33 11.1 0.0 1.4 1 0 0 1 1 1 0 ImpA, N-terminal, type VI secretion system RNase_T PF00929.24 EAQ90780.1 - 7e-13 49.4 0.0 3.5e-10 40.7 0.0 2.9 2 1 0 2 2 2 2 Exonuclease PGM_PMM_I PF02878.16 EAQ90781.1 - 2e-33 115.0 0.0 2.9e-33 114.5 0.0 1.2 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 EAQ90781.1 - 1.5e-25 89.6 0.0 3.3e-25 88.5 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 EAQ90781.1 - 2.5e-16 60.1 0.0 6e-16 58.9 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 EAQ90781.1 - 1.4e-05 25.2 0.0 3e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain DUF4844 PF16133.5 EAQ90781.1 - 0.029 14.9 0.4 0.072 13.6 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4844) 7tm_3 PF00003.22 EAQ90782.1 - 0.028 14.2 0.2 0.033 13.9 0.2 1.1 1 0 0 1 1 1 0 7 transmembrane sweet-taste receptor of 3 GCPR HMG_box PF00505.19 EAQ90783.1 - 1.6e-25 89.3 0.7 2.7e-25 88.6 0.7 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EAQ90783.1 - 2.9e-18 66.2 1.3 4.8e-18 65.5 1.3 1.3 1 0 0 1 1 1 1 HMG-box domain Ccdc124 PF06244.12 EAQ90783.1 - 0.0014 19.2 1.5 0.0024 18.4 0.0 1.9 1 1 1 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 HMG_box_5 PF14887.6 EAQ90783.1 - 0.018 15.0 0.2 0.041 13.8 0.2 1.6 1 0 0 1 1 1 0 HMG (high mobility group) box 5 CHDNT PF08073.12 EAQ90783.1 - 0.027 14.4 0.0 0.049 13.6 0.0 1.4 1 0 0 1 1 1 0 CHDNT (NUC034) domain ATG11 PF10377.9 EAQ90785.1 - 1.6e-40 138.1 0.0 1.6e-40 138.1 0.0 3.7 4 0 0 4 4 4 1 Autophagy-related protein 11 NuA4 PF09340.10 EAQ90785.1 - 1.8e-05 24.5 2.0 0.25 11.2 0.0 4.4 3 0 0 3 3 3 2 Histone acetyltransferase subunit NuA4 HMMR_N PF15905.5 EAQ90785.1 - 0.00027 20.5 13.6 0.00027 20.5 13.6 3.3 2 1 1 3 3 2 1 Hyaluronan mediated motility receptor N-terminal Tropomyosin PF00261.20 EAQ90785.1 - 0.00036 20.0 5.9 0.00036 20.0 5.9 4.9 3 1 0 4 4 4 1 Tropomyosin FERM_f0 PF16511.5 EAQ90785.1 - 0.015 15.6 0.2 2.5 8.5 0.0 2.6 2 0 0 2 2 2 0 N-terminal or F0 domain of Talin-head FERM HicA_toxin PF07927.12 EAQ90785.1 - 0.015 15.3 0.0 0.034 14.2 0.0 1.5 1 0 0 1 1 1 0 HicA toxin of bacterial toxin-antitoxin, FOXP-CC PF16159.5 EAQ90785.1 - 0.47 11.1 5.4 6.3 7.5 0.0 4.1 3 0 0 3 3 2 0 FOXP coiled-coil domain Spc7 PF08317.11 EAQ90785.1 - 0.49 9.2 58.0 0.071 12.0 8.7 5.3 3 1 2 6 6 6 0 Spc7 kinetochore protein DUF4407 PF14362.6 EAQ90785.1 - 0.56 9.5 39.0 0.034 13.5 1.7 4.5 2 1 2 4 4 4 0 Domain of unknown function (DUF4407) HAP1_N PF04849.13 EAQ90785.1 - 2.4 7.3 56.4 0.051 12.8 3.7 4.1 3 1 1 4 4 4 0 HAP1 N-terminal conserved region Fez1 PF06818.15 EAQ90785.1 - 7.4 7.0 60.1 1.6 9.1 15.3 5.4 2 1 1 4 4 3 0 Fez1 AATase PF07247.12 EAQ90786.1 - 2.2e-16 59.5 0.0 3.3e-16 58.9 0.0 1.1 1 0 0 1 1 1 1 Alcohol acetyltransferase Ribosomal_L9_N PF01281.19 EAQ90786.1 - 1.5e-09 37.3 0.0 3.3e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain Condensation PF00668.20 EAQ90786.1 - 0.15 10.7 0.0 1.8 7.1 0.0 2.1 2 0 0 2 2 2 0 Condensation domain LSM PF01423.22 EAQ90789.1 - 6e-18 64.3 0.1 7.4e-18 64.0 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EAQ90789.1 - 0.00015 21.8 0.1 0.0002 21.5 0.1 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 EAQ90789.1 - 0.0015 18.6 0.1 0.0017 18.4 0.1 1.2 1 0 0 1 1 1 1 Scd6-like Sm domain Hfq PF17209.3 EAQ90789.1 - 0.13 12.0 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Hfq protein SPAN PF02510.14 EAQ90789.1 - 0.21 10.7 0.0 0.23 10.6 0.0 1.1 1 0 0 1 1 1 0 Surface presentation of antigens protein HSP20 PF00011.21 EAQ90790.1 - 6.4e-17 61.6 0.0 2.3e-12 47.0 0.0 2.2 2 0 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 EAQ90790.1 - 7.6e-05 22.2 0.0 0.013 15.0 0.0 2.2 2 0 0 2 2 2 2 HSP20-like domain found in ArsA YTH PF04146.15 EAQ90791.1 - 7.2e-60 201.7 0.0 1e-59 201.2 0.0 1.2 1 0 0 1 1 1 1 YT521-B-like domain Proteasome PF00227.26 EAQ90792.1 - 2.4e-28 98.9 0.2 7.2e-28 97.4 0.2 1.9 1 1 0 1 1 1 1 Proteasome subunit PI3_PI4_kinase PF00454.27 EAQ90793.1 - 1.7e-39 136.1 0.0 2.9e-37 128.8 0.0 2.3 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 EAQ90793.1 - 6.2e-24 84.4 0.1 1.4e-23 83.2 0.1 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Cation_efflux PF01545.21 EAQ90794.1 - 1e-21 77.6 0.7 1.3e-21 77.2 0.7 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 EAQ90794.1 - 8.6e-06 25.8 0.0 1.6e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter BLOC1S3 PF15753.5 EAQ90796.1 - 2.7 8.1 5.2 7.8 6.6 1.6 2.5 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 CDC45 PF02724.14 EAQ90796.1 - 4.5 5.4 6.5 7.9 4.6 6.5 1.3 1 0 0 1 1 1 0 CDC45-like protein DMRL_synthase PF00885.19 EAQ90797.1 - 3.4e-58 195.4 0.0 4.2e-58 195.2 0.0 1.1 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase HATPase_c_3 PF13589.6 EAQ90798.1 - 1.5e-12 47.5 0.0 2.9e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_mis_repair PF01119.19 EAQ90798.1 - 3.3e-09 36.4 0.0 7.2e-09 35.4 0.0 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c PF02518.26 EAQ90798.1 - 9.7e-07 29.3 0.0 2.8e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TRP PF06011.12 EAQ90799.1 - 9.8e-38 130.0 21.6 2.8e-36 125.2 21.6 2.1 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 EAQ90799.1 - 4.8e-22 78.8 0.1 1.2e-21 77.5 0.0 1.7 2 0 0 2 2 2 1 ML-like domain ATP-synt_I PF03899.15 EAQ90799.1 - 0.0086 16.4 1.3 0.0086 16.4 1.3 3.0 2 1 0 3 3 3 1 ATP synthase I chain DUF3899 PF13038.6 EAQ90799.1 - 0.05 14.1 0.5 0.22 12.0 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) WD40 PF00400.32 EAQ90802.1 - 6.4e-13 49.0 3.9 0.21 12.5 0.1 6.5 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAQ90802.1 - 0.011 16.1 0.0 3.1 8.2 0.0 3.7 4 2 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain RNA_pol_Rpb4 PF03874.16 EAQ90803.1 - 1.3e-25 90.1 2.7 1.6e-25 89.8 2.7 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 CPL PF08144.11 EAQ90804.1 - 6.2e-39 133.6 0.0 3.5e-37 127.9 0.0 3.3 4 0 0 4 4 4 1 CPL (NUC119) domain CTI PF06934.11 EAQ90804.1 - 0.0046 15.5 0.1 0.0079 14.8 0.1 1.3 1 0 0 1 1 1 1 Fatty acid cis/trans isomerase (CTI) RWD PF05773.22 EAQ90805.1 - 8.7e-25 87.3 1.7 1.4e-24 86.6 1.7 1.3 1 0 0 1 1 1 1 RWD domain DFRP_C PF16543.5 EAQ90805.1 - 0.00014 22.2 8.6 0.00024 21.5 8.0 1.8 1 1 0 1 1 1 1 DRG Family Regulatory Proteins, Tma46 DUF2852 PF11014.8 EAQ90805.1 - 0.13 12.4 2.5 0.21 11.7 2.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2852) TPR_19 PF14559.6 EAQ90806.1 - 1.9e-07 31.5 0.9 0.0059 17.1 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EAQ90806.1 - 4.5e-06 26.4 0.1 0.026 14.6 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 EAQ90806.1 - 6.3e-05 22.9 0.0 0.029 14.6 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_MalT PF17874.1 EAQ90806.1 - 7.9e-05 22.2 4.6 0.095 12.0 0.2 2.2 2 0 0 2 2 2 2 MalT-like TPR region TPR_7 PF13176.6 EAQ90806.1 - 0.00021 21.1 0.1 0.011 15.7 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 EAQ90806.1 - 0.00028 21.1 0.8 0.084 13.2 0.7 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 EAQ90806.1 - 0.0016 19.0 1.4 0.0016 19.0 1.4 3.6 4 1 1 5 5 4 1 Tetratricopeptide repeat Ring_hydroxyl_B PF00866.18 EAQ90806.1 - 0.016 15.2 0.5 0.088 12.9 0.3 2.0 2 0 0 2 2 2 0 Ring hydroxylating beta subunit HrpB1_HrpK PF09613.10 EAQ90806.1 - 0.018 14.7 3.0 0.023 14.3 0.2 2.5 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_14 PF13428.6 EAQ90806.1 - 0.03 15.1 11.2 0.17 12.8 0.1 5.3 5 2 2 7 7 7 0 Tetratricopeptide repeat TPR_9 PF13371.6 EAQ90806.1 - 0.035 14.2 6.0 0.44 10.7 0.1 3.5 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 EAQ90806.1 - 0.053 13.4 0.0 0.53 10.2 0.0 2.6 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF2681 PF10883.8 EAQ90806.1 - 0.13 12.7 0.2 0.13 12.7 0.2 1.8 2 0 0 2 2 1 0 Protein of unknown function (DUF2681) TPR_4 PF07721.14 EAQ90806.1 - 0.13 12.9 0.5 0.13 12.9 0.5 3.7 4 0 0 4 4 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 EAQ90806.1 - 2.4 9.0 6.5 21 6.0 0.0 4.2 4 0 0 4 4 3 0 Tetratricopeptide repeat CFEM PF05730.11 EAQ90807.1 - 0.0025 17.9 5.5 0.0042 17.1 5.5 1.3 1 0 0 1 1 1 1 CFEM domain MutS_V PF00488.21 EAQ90808.1 - 1.5e-44 152.3 0.0 2.5e-44 151.5 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EAQ90808.1 - 1.7e-14 54.5 0.2 4.3e-14 53.2 0.2 1.7 1 0 0 1 1 1 1 MutS domain III Hpt PF01627.23 EAQ90808.1 - 0.14 12.4 0.7 1.2 9.4 0.1 2.7 2 1 0 2 2 2 0 Hpt domain MMgT PF10270.9 EAQ90809.1 - 1.3e-31 108.9 0.0 1.7e-31 108.5 0.0 1.1 1 0 0 1 1 1 1 Membrane magnesium transporter HMG_box PF00505.19 EAQ90810.1 - 1.2e-09 38.5 2.9 1.2e-09 38.5 2.9 2.0 2 0 0 2 2 2 1 HMG (high mobility group) box MATalpha_HMGbox PF04769.12 EAQ90810.1 - 0.0054 16.1 0.1 0.0097 15.2 0.1 1.4 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 HMG-box HMG_box_2 PF09011.10 EAQ90810.1 - 0.024 15.2 1.3 0.053 14.1 1.3 1.6 1 0 0 1 1 1 0 HMG-box domain PHD PF00628.29 EAQ90811.1 - 2.7e-08 33.6 9.7 4.9e-08 32.8 9.7 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 EAQ90811.1 - 0.032 13.8 5.5 0.059 12.9 5.5 1.4 1 0 0 1 1 1 0 PHD-finger Ion_trans PF00520.31 EAQ90812.1 - 1.9e-104 348.2 62.4 1.4e-33 116.1 13.0 5.8 4 2 0 4 4 4 4 Ion transport protein SUIM_assoc PF16619.5 EAQ90812.1 - 0.00079 19.5 1.5 0.0034 17.4 1.5 2.1 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 EAQ90812.1 - 5.7 6.5 7.8 12 5.5 7.8 1.4 1 0 0 1 1 1 0 Spt20 family Cyclin_N PF00134.23 EAQ90815.1 - 6.9e-45 151.9 0.0 1.7e-44 150.7 0.0 1.7 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EAQ90815.1 - 2.1e-33 114.9 0.1 3.9e-33 114.1 0.1 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain HEPN_Toprim_N PF18871.1 EAQ90815.1 - 0.073 13.0 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 HEPN/Toprim N-terminal domain 1 Ribosomal_L2_C PF03947.18 EAQ90816.1 - 5.5e-37 126.8 0.7 1e-36 125.9 0.7 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 EAQ90816.1 - 0.084 12.8 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Ribosomal Proteins L2, RNA binding domain PAP2 PF01569.21 EAQ90817.1 - 6.2e-22 77.8 4.6 6.2e-22 77.8 4.6 3.1 2 1 0 2 2 2 1 PAP2 superfamily Sulf_transp PF04143.14 EAQ90817.1 - 0.0068 16.0 2.0 0.0068 16.0 2.0 1.6 2 0 0 2 2 2 1 Sulphur transport DUF5368 PF17336.2 EAQ90817.1 - 0.054 13.7 0.9 0.14 12.4 0.9 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5368) PRA1 PF03208.19 EAQ90817.1 - 0.49 10.0 3.1 0.41 10.3 0.9 2.0 2 0 0 2 2 2 0 PRA1 family protein CK_II_beta PF01214.18 EAQ90818.1 - 3.2e-70 235.7 1.0 1.7e-37 129.0 0.0 2.1 2 0 0 2 2 2 2 Casein kinase II regulatory subunit Cwf_Cwc_15 PF04889.12 EAQ90818.1 - 0.44 10.2 2.8 0.67 9.6 2.8 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein GST_C_5 PF16865.5 EAQ90819.1 - 0.0029 18.1 0.0 0.0051 17.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EAQ90819.1 - 0.0052 16.8 0.1 0.014 15.4 0.1 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EAQ90819.1 - 0.014 15.6 0.0 0.035 14.3 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EAQ90819.1 - 0.063 13.5 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain RIC1 PF07064.13 EAQ90820.1 - 5.9e-94 314.2 0.0 8.5e-94 313.7 0.0 1.2 1 0 0 1 1 1 1 RIC1 WD40 PF00400.32 EAQ90820.1 - 0.09 13.7 1.3 13 6.8 0.1 4.3 4 0 0 4 4 4 0 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAQ90820.1 - 0.096 13.0 0.0 9.7 6.6 0.0 3.4 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EAQ90821.1 - 3.8e-08 33.8 0.1 0.021 15.7 0.0 3.4 3 0 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.8 EAQ90821.1 - 2.2e-07 29.9 0.8 0.0075 15.0 0.1 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 EAQ90821.1 - 7.4e-05 23.0 0.2 0.67 10.3 0.1 3.1 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain DUF1513 PF07433.11 EAQ90821.1 - 0.012 14.7 0.0 0.021 13.9 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1513) Hira PF07569.11 EAQ90821.1 - 0.039 13.7 0.2 5.8 6.6 0.1 2.1 1 1 1 2 2 2 0 TUP1-like enhancer of split Fungal_trans PF04082.18 EAQ90822.1 - 7.8e-19 67.7 0.1 1.3e-18 67.0 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EAQ90822.1 - 2.3e-08 34.0 8.7 2.3e-08 34.0 8.7 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.24 EAQ90823.1 - 2.3e-17 63.0 12.9 6.8e-13 48.3 12.9 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter DUF4131 PF13567.6 EAQ90823.1 - 2.2 7.9 8.1 1.6 8.3 1.4 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) Trep_Strep PF09605.10 EAQ90823.1 - 2.3 8.2 12.4 0.22 11.5 3.9 2.3 1 1 1 2 2 2 0 Hypothetical bacterial integral membrane protein (Trep_Strep) Sigma70_r4 PF04545.16 EAQ90824.1 - 0.0024 17.4 0.3 0.34 10.5 0.1 3.3 3 0 0 3 3 3 1 Sigma-70, region 4 HTH_23 PF13384.6 EAQ90824.1 - 0.0026 17.5 1.6 0.11 12.4 0.1 2.4 2 0 0 2 2 2 1 Homeodomain-like domain HTH_AsnC-type PF13404.6 EAQ90824.1 - 0.0053 16.6 2.0 0.0076 16.1 0.3 2.1 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain HTH_Tnp_Tc3_2 PF01498.18 EAQ90824.1 - 0.031 14.5 1.2 2.2 8.6 0.0 2.9 3 0 0 3 3 3 0 Transposase HTH_29 PF13551.6 EAQ90824.1 - 0.058 13.4 1.3 0.35 10.9 0.0 2.4 2 0 0 2 2 2 0 Winged helix-turn helix HTH_11 PF08279.12 EAQ90824.1 - 0.14 12.1 0.2 12 5.9 0.1 2.4 2 0 0 2 2 2 0 HTH domain HTH_17 PF12728.7 EAQ90824.1 - 0.25 11.6 1.3 9.3 6.5 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain Acetate_kinase PF00871.17 EAQ90825.1 - 2.2e-80 270.3 0.0 1.6e-66 224.6 0.0 2.1 2 0 0 2 2 2 2 Acetokinase family Trypan_PARP PF05887.11 EAQ90825.1 - 0.00064 19.7 0.8 0.0016 18.4 0.8 1.6 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) zf-C2H2 PF00096.26 EAQ90826.1 - 0.00049 20.4 9.0 0.005 17.2 1.8 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EAQ90826.1 - 0.0057 17.0 2.5 0.0057 17.0 2.5 2.7 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 EAQ90826.1 - 0.076 13.9 6.7 0.19 12.7 0.9 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger Integrin_B_tail PF07965.12 EAQ90826.1 - 0.1 13.1 1.3 0.43 11.1 0.1 2.0 1 1 1 2 2 2 0 Integrin beta tail domain zf-C2H2_aberr PF17017.5 EAQ90826.1 - 0.14 12.3 0.6 0.21 11.7 0.6 1.2 1 0 0 1 1 1 0 Aberrant zinc-finger zf-met PF12874.7 EAQ90826.1 - 0.26 11.7 1.4 0.3 11.6 0.1 1.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2HE PF16278.5 EAQ90826.1 - 0.27 11.7 2.5 0.48 10.9 2.5 1.4 1 0 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger Nop PF01798.18 EAQ90829.1 - 7.9e-73 244.7 0.0 1.2e-72 244.2 0.0 1.3 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 EAQ90829.1 - 2.2e-41 141.6 1.0 6.5e-41 140.0 1.0 1.9 1 1 0 1 1 1 1 Prp31 C terminal domain HAT PF02184.16 EAQ90830.1 - 6.4e-24 83.6 63.4 5.2e-11 42.3 0.4 12.7 14 0 0 14 14 13 5 HAT (Half-A-TPR) repeat TPR_14 PF13428.6 EAQ90830.1 - 9.5e-23 78.9 31.5 1.8e-05 25.2 0.2 11.5 8 2 4 12 12 12 6 Tetratricopeptide repeat TPR_19 PF14559.6 EAQ90830.1 - 6.3e-20 71.5 3.6 7.4e-08 32.8 0.0 7.2 6 1 0 7 7 7 2 Tetratricopeptide repeat Suf PF05843.14 EAQ90830.1 - 2.4e-17 63.9 11.9 1e-05 25.7 0.0 6.9 3 1 4 7 7 7 4 Suppressor of forked protein (Suf) TPR_15 PF13429.6 EAQ90830.1 - 2.1e-08 33.8 10.4 0.018 14.3 0.8 5.8 2 1 3 6 6 6 3 Tetratricopeptide repeat TPR_6 PF13174.6 EAQ90830.1 - 1.8e-07 31.3 15.5 0.62 10.8 0.0 9.2 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_8 PF13181.6 EAQ90830.1 - 3.9e-06 26.6 2.7 2.7 8.4 0.0 6.6 7 0 0 7 7 5 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EAQ90830.1 - 6.8e-05 22.9 2.9 0.71 10.0 0.0 5.5 5 0 0 5 5 5 1 Fis1 C-terminal tetratricopeptide repeat TPR_9 PF13371.6 EAQ90830.1 - 8.9e-05 22.6 1.9 2.8 8.1 0.2 5.2 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 EAQ90830.1 - 0.00047 20.8 12.6 0.52 11.0 0.1 6.8 7 2 2 9 9 7 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EAQ90830.1 - 0.0018 18.4 0.4 1.1 9.5 0.0 4.0 4 0 0 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 YfiO PF13525.6 EAQ90830.1 - 0.0029 17.4 0.2 0.017 14.9 0.0 2.4 2 1 0 2 2 2 1 Outer membrane lipoprotein TPR_17 PF13431.6 EAQ90830.1 - 0.005 17.1 7.8 8.9 7.0 0.0 6.5 8 0 0 8 8 6 1 Tetratricopeptide repeat TPR_2 PF07719.17 EAQ90830.1 - 0.0074 16.3 23.9 0.0081 16.2 0.1 8.3 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_1 PF00515.28 EAQ90830.1 - 0.048 13.5 4.4 3.6 7.6 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat QIL1 PF15884.5 EAQ90830.1 - 0.053 14.1 0.1 6.6 7.4 0.0 3.8 4 0 0 4 4 4 0 MICOS complex subunit MIC13, QIL1 U3_assoc_6 PF08640.11 EAQ90830.1 - 0.063 13.4 16.8 0.089 12.9 1.0 5.9 4 2 2 6 6 6 0 U3 small nucleolar RNA-associated protein 6 TPR_12 PF13424.6 EAQ90830.1 - 2.7 8.4 18.8 4.3 7.7 0.1 7.4 10 0 0 10 10 9 0 Tetratricopeptide repeat c-SKI_SMAD_bind PF08782.10 EAQ90830.1 - 3.1 8.1 8.1 3.1 8.1 0.2 4.3 5 0 0 5 5 4 0 c-SKI Smad4 binding domain HLH PF00010.26 EAQ90832.1 - 5.1e-06 26.4 0.0 8.7e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain La PF05383.17 EAQ90833.1 - 4.8e-16 58.6 0.0 9.2e-16 57.6 0.0 1.4 1 0 0 1 1 1 1 La domain DUF4087 PF13316.6 EAQ90834.1 - 0.0043 17.5 0.1 0.0058 17.1 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4087) NPR3 PF03666.13 EAQ90837.1 - 6.7e-132 440.6 7.0 2.5e-131 438.7 0.0 3.0 2 1 0 2 2 2 1 Nitrogen Permease regulator of amino acid transport activity 3 Herpes_LMP1 PF05297.11 EAQ90837.1 - 1.8 7.7 11.8 3.7 6.6 11.8 1.5 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) SOG2 PF10428.9 EAQ90837.1 - 3.3 6.8 20.4 5.6 6.0 20.4 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein Choline_kinase PF01633.20 EAQ90838.1 - 6.3e-55 186.0 0.0 2.6e-54 184.0 0.0 1.8 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.23 EAQ90838.1 - 1.4e-10 41.6 0.0 3.7e-10 40.1 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family GCV_T PF01571.21 EAQ90839.1 - 1.9e-83 279.8 0.0 2.4e-83 279.4 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 EAQ90839.1 - 4.6e-21 74.5 0.8 1.4e-20 73.0 0.8 1.8 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain HA2 PF04408.23 EAQ90840.1 - 1.1e-21 77.1 2.8 1.2e-21 77.0 0.0 2.4 3 0 0 3 3 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EAQ90840.1 - 8.5e-17 61.3 0.0 2.3e-16 59.9 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EAQ90840.1 - 4.3e-13 49.6 0.0 1e-12 48.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EAQ90840.1 - 8.6e-09 35.4 0.1 1.6e-08 34.5 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAQ90840.1 - 8.7e-05 22.8 0.1 0.00025 21.3 0.1 1.7 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 EAQ90840.1 - 0.00016 21.0 0.0 0.00029 20.2 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 EAQ90840.1 - 0.00017 22.0 0.1 0.0004 20.8 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EAQ90840.1 - 0.00029 20.6 0.0 0.00062 19.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 EAQ90840.1 - 0.0022 18.0 0.0 0.42 10.6 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SRP54 PF00448.22 EAQ90840.1 - 0.0043 16.7 0.3 0.011 15.3 0.3 1.7 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain Flavi_DEAD PF07652.14 EAQ90840.1 - 0.0053 16.7 0.0 0.0099 15.9 0.0 1.4 1 0 0 1 1 1 1 Flavivirus DEAD domain T2SSE PF00437.20 EAQ90840.1 - 0.012 14.7 0.0 0.026 13.6 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein ATPase PF06745.13 EAQ90840.1 - 0.039 13.3 0.0 0.082 12.2 0.0 1.5 1 0 0 1 1 1 0 KaiC PhoH PF02562.16 EAQ90840.1 - 0.054 12.9 0.0 0.13 11.7 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_14 PF13173.6 EAQ90840.1 - 0.19 11.7 0.5 1.6 8.7 0.5 2.4 1 1 0 1 1 1 0 AAA domain DUF592 PF04574.13 EAQ90840.1 - 0.82 9.4 2.4 7.7 6.3 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF592) WD40 PF00400.32 EAQ90841.1 - 3.8e-15 56.0 10.2 0.012 16.5 0.0 5.9 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAQ90841.1 - 2.4e-07 30.9 0.1 0.0044 17.3 0.2 4.4 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EAQ90841.1 - 6.5e-05 21.8 0.5 0.00039 19.2 0.4 2.2 2 1 1 3 3 3 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 EAQ90841.1 - 0.021 13.6 0.0 1.4 7.6 0.0 2.5 2 1 1 3 3 3 0 Nup133 N terminal like TFIIA PF03153.13 EAQ90843.1 - 2.4 8.1 24.9 3.2 7.6 24.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Hep_59 PF07052.11 EAQ90844.1 - 7.8e-20 71.6 1.6 1.6e-19 70.6 0.0 2.3 2 0 0 2 2 2 1 Hepatocellular carcinoma-associated antigen 59 BRF1 PF07741.13 EAQ90844.1 - 4.5 7.7 8.8 3.6 8.0 0.6 3.0 2 1 1 3 3 3 0 Brf1-like TBP-binding domain SKG6 PF08693.10 EAQ90845.1 - 0.0088 15.4 0.4 0.023 14.1 0.4 1.8 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Rax2 PF12768.7 EAQ90845.1 - 0.19 11.2 0.0 0.25 10.8 0.0 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity DUF846 PF05832.12 EAQ90846.1 - 6.9e-46 155.7 5.5 8.4e-46 155.5 5.5 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) DUF5504 PF17608.2 EAQ90846.1 - 0.043 13.9 1.3 0.043 13.9 1.3 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5504) ABC2_membrane_3 PF12698.7 EAQ90846.1 - 3.4 6.7 9.6 0.047 12.8 1.5 1.7 2 0 0 2 2 2 0 ABC-2 family transporter protein HpcH_HpaI PF03328.14 EAQ90847.1 - 4.5e-42 143.7 0.8 4.5e-42 143.7 0.8 1.9 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 EAQ90847.1 - 2.7e-14 53.1 0.1 1.5e-07 30.9 0.0 2.1 2 0 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold RRM_1 PF00076.22 EAQ90849.1 - 1.6e-19 69.5 0.0 2.3e-19 68.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EAQ90849.1 - 0.012 15.7 0.0 0.02 15.0 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif ChaC PF04752.12 EAQ90850.1 - 2.9e-36 125.2 0.0 4.5e-36 124.6 0.0 1.2 1 0 0 1 1 1 1 ChaC-like protein EF-hand_1 PF00036.32 EAQ90851.1 - 1.2e-25 87.1 7.7 1.1e-06 27.7 0.1 5.3 5 0 0 5 5 5 5 EF hand EF-hand_6 PF13405.6 EAQ90851.1 - 4.8e-22 76.0 6.5 5.8e-05 22.7 0.1 5.3 5 0 0 5 5 5 5 EF-hand domain EF-hand_7 PF13499.6 EAQ90851.1 - 3.7e-21 75.4 7.4 5.4e-10 39.6 0.0 4.0 3 1 0 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.6 EAQ90851.1 - 5.1e-19 67.9 10.4 2e-09 37.1 0.0 5.0 3 2 2 5 5 5 5 EF-hand domain pair EF-hand_5 PF13202.6 EAQ90851.1 - 6.3e-17 60.2 4.0 0.00012 21.4 0.3 4.5 4 0 0 4 4 4 4 EF hand C1_2 PF03107.16 EAQ90852.1 - 9.7 6.6 11.2 2.3 8.6 7.6 1.8 2 0 0 2 2 2 0 C1 domain 2OG-FeII_Oxy PF03171.20 EAQ90853.1 - 1.8e-13 50.8 0.0 1.1e-12 48.3 0.0 2.4 2 1 1 3 3 3 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 EAQ90853.1 - 4.7e-10 40.2 0.0 7.8e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal CysA_C_terminal PF17850.1 EAQ90853.1 - 0.002 18.6 0.1 0.0091 16.5 0.1 2.2 1 0 0 1 1 1 1 CysA C-terminal regulatory domain Atrophin-1 PF03154.15 EAQ90854.1 - 0.041 12.2 1.7 0.053 11.8 1.7 1.1 1 0 0 1 1 1 0 Atrophin-1 family TFIIA PF03153.13 EAQ90855.1 - 0.047 13.7 28.2 0.07 13.1 28.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF674 PF05056.12 EAQ90855.1 - 0.089 11.6 1.7 0.13 11.1 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF674) SelP_N PF04592.14 EAQ90855.1 - 0.65 9.3 13.9 1.1 8.6 13.9 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Androgen_recep PF02166.16 EAQ90855.1 - 0.7 8.7 26.1 0.8 8.5 23.2 2.1 2 0 0 2 2 2 0 Androgen receptor RskA PF10099.9 EAQ90855.1 - 1.1 9.5 12.5 9.2 6.5 12.9 2.3 2 1 0 3 3 3 0 Anti-sigma-K factor rskA Spem1 PF15670.5 EAQ90855.1 - 1.8 8.1 14.2 3.6 7.1 14.2 1.4 1 0 0 1 1 1 0 Spermatid maturation protein 1 Rad51 PF08423.11 EAQ90856.1 - 1.6e-126 420.8 0.0 1.9e-126 420.5 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 EAQ90856.1 - 5.2e-10 39.2 0.0 7.6e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain RecA PF00154.21 EAQ90856.1 - 9e-08 31.9 0.0 1.3e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.6 EAQ90856.1 - 3.2e-06 27.7 0.7 8.4e-06 26.3 0.7 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix domain ATPase PF06745.13 EAQ90856.1 - 7.1e-05 22.3 0.2 0.0002 20.8 0.2 1.8 1 1 0 1 1 1 1 KaiC Lyase_8_C PF02884.17 EAQ90856.1 - 0.036 14.5 0.1 0.078 13.5 0.1 1.5 1 0 0 1 1 1 0 Polysaccharide lyase family 8, C-terminal beta-sandwich domain DnaB_C PF03796.15 EAQ90856.1 - 0.04 13.3 0.1 0.18 11.1 0.0 1.9 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain AAA_24 PF13479.6 EAQ90856.1 - 0.065 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain PAXNEB PF05625.11 EAQ90856.1 - 0.1 11.8 0.3 0.8 8.8 0.1 2.0 2 0 0 2 2 2 0 PAXNEB protein Sun2_CC2 PF18580.1 EAQ90856.1 - 0.14 12.4 0.3 0.41 10.9 0.0 1.9 2 0 0 2 2 2 0 SUN2 coiled coil domain 2 Nup160 PF11715.8 EAQ90857.1 - 4.2e-157 524.0 0.0 2.1e-96 323.7 0.0 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Vps26 PF03643.15 EAQ90858.1 - 5.5e-131 435.6 0.6 6.4e-131 435.4 0.6 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 EAQ90858.1 - 0.00039 20.5 0.5 1 9.4 0.0 3.6 2 1 2 4 4 4 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 EAQ90858.1 - 0.0072 16.8 0.0 0.072 13.5 0.0 2.4 1 1 1 2 2 2 1 Arrestin (or S-antigen), C-terminal domain IL17R_D_N PF16742.5 EAQ90858.1 - 0.069 13.2 0.1 0.14 12.2 0.1 1.4 1 0 0 1 1 1 0 N-terminus of interleukin 17 receptor D Ribosomal_L6 PF00347.23 EAQ90859.1 - 1e-25 90.2 8.7 1.2e-12 48.3 3.1 2.2 2 0 0 2 2 2 2 Ribosomal protein L6 Phage_holin_3_6 PF07332.11 EAQ90860.1 - 0.02 14.9 4.9 0.44 10.6 1.3 2.4 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III DUF1304 PF06993.12 EAQ90860.1 - 0.093 12.7 1.3 0.2 11.6 1.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1304) V-ATPase_H_N PF03224.14 EAQ90861.1 - 1.7e-39 135.9 0.0 2e-39 135.8 0.0 1.0 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 EAQ90862.1 - 3.6e-35 120.6 0.0 8.3e-35 119.4 0.0 1.6 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_N PF03224.14 EAQ90862.1 - 4.2e-05 23.0 0.0 5.9e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 V-ATPase subunit H ABC_tran_CTD PF16326.5 EAQ90862.1 - 0.052 13.8 0.0 0.15 12.4 0.0 1.7 1 0 0 1 1 1 0 ABC transporter C-terminal domain RIX1 PF08167.12 EAQ90862.1 - 0.16 11.7 0.0 4.5 7.0 0.0 2.5 2 1 1 3 3 3 0 rRNA processing/ribosome biogenesis DUF2666 PF10869.8 EAQ90862.1 - 0.18 12.0 0.7 33 4.7 0.0 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2666) Acylphosphatase PF00708.18 EAQ90863.1 - 4.9e-08 33.3 0.1 1.7e-07 31.5 0.1 1.7 1 1 0 1 1 1 1 Acylphosphatase DUF726 PF05277.12 EAQ90864.1 - 3.7e-90 302.3 0.0 4.4e-90 302.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Fcf1 PF04900.12 EAQ90865.1 - 2e-17 63.4 0.0 3.7e-17 62.6 0.0 1.4 1 0 0 1 1 1 1 Fcf1 CDC45 PF02724.14 EAQ90865.1 - 2.2 6.5 7.5 2.7 6.2 7.5 1.1 1 0 0 1 1 1 0 CDC45-like protein SpoIIE PF07228.12 EAQ90866.1 - 0.00022 21.2 0.0 0.0015 18.5 0.0 2.1 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 EAQ90866.1 - 0.088 12.4 0.1 0.43 10.2 0.0 1.9 2 0 0 2 2 2 0 Protein phosphatase 2C PH PF00169.29 EAQ90867.1 - 2.7e-07 31.1 0.4 2.7e-06 27.8 0.0 2.5 2 1 0 2 2 2 1 PH domain PH_9 PF15410.6 EAQ90867.1 - 0.0014 19.0 0.1 0.0068 16.8 0.0 2.2 3 0 0 3 3 3 1 Pleckstrin homology domain PDGLE PF13190.6 EAQ90867.1 - 0.22 11.4 0.3 0.69 9.8 0.3 1.9 1 1 0 1 1 1 0 PDGLE domain Pkinase PF00069.25 EAQ90869.1 - 3.8e-63 213.3 0.0 9.7e-63 212.0 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ90869.1 - 5.4e-29 101.3 0.0 9.2e-29 100.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 EAQ90869.1 - 6.7e-10 39.2 0.3 3.9e-07 30.3 0.0 3.1 3 0 0 3 3 3 2 FHA domain Kdo PF06293.14 EAQ90869.1 - 0.0042 16.5 0.0 0.0078 15.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EAQ90869.1 - 0.012 15.5 0.5 4.2 7.2 0.1 2.9 2 1 1 3 3 3 0 Phosphotransferase enzyme family Yop-YscD_cpl PF16697.5 EAQ90869.1 - 0.017 15.4 0.0 0.043 14.1 0.0 1.6 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain DNA_pol3_a_NII PF11490.8 EAQ90870.1 - 6.1 6.8 7.3 13 5.8 7.3 1.4 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus II STT3 PF02516.14 EAQ90871.1 - 1.1e-135 453.3 32.9 5.8e-131 437.8 30.6 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit Cytomega_TRL10 PF06084.11 EAQ90871.1 - 0.097 12.7 0.1 0.33 11.0 0.1 1.9 1 0 0 1 1 1 0 Cytomegalovirus TRL10 protein Ribosomal_L29 PF00831.23 EAQ90872.1 - 2.7e-17 62.4 0.8 2.7e-17 62.4 0.8 2.0 2 1 0 2 2 2 1 Ribosomal L29 protein Ribosomal_S9 PF00380.19 EAQ90872.1 - 0.002 18.6 0.4 0.0024 18.4 0.4 1.3 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Ribosomal_L6e PF01159.19 EAQ90873.1 - 3.3e-40 137.1 0.3 4.9e-40 136.5 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L6e V-SNARE_C PF12352.8 EAQ90874.1 - 2.3e-12 47.0 3.6 1.5e-11 44.4 0.1 2.5 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus SATase_N PF06426.14 EAQ90874.1 - 0.28 11.6 4.2 0.22 11.9 1.0 2.1 2 0 0 2 2 2 0 Serine acetyltransferase, N-terminal CorA PF01544.18 EAQ90874.1 - 2 7.7 4.8 2.5 7.3 3.8 1.7 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein ATP-synt_10 PF05176.14 EAQ90875.1 - 5.5e-77 258.5 0.0 6.9e-77 258.2 0.0 1.0 1 0 0 1 1 1 1 ATP10 protein Pertus-S4-tox PF09275.10 EAQ90875.1 - 0.11 12.8 0.1 0.21 11.9 0.1 1.4 1 0 0 1 1 1 0 Pertussis toxin S4 subunit 2-oxoacid_dh PF00198.23 EAQ90876.1 - 1.8e-67 227.2 0.0 2.3e-67 226.8 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 EAQ90876.1 - 1.2e-16 60.2 0.0 2.7e-16 59.2 0.0 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme SKI PF01202.22 EAQ90877.1 - 1.5e-15 57.7 0.0 1.8e-15 57.4 0.0 1.1 1 0 0 1 1 1 1 Shikimate kinase AAA_18 PF13238.6 EAQ90877.1 - 5.7e-11 43.1 0.0 9.5e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EAQ90877.1 - 5.7e-09 36.3 0.0 8.6e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 EAQ90877.1 - 4.7e-07 30.3 0.0 1.3e-06 28.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 EAQ90877.1 - 1.5e-06 28.6 0.1 6.7e-06 26.6 0.1 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Cytidylate_kin PF02224.18 EAQ90877.1 - 1.8e-05 24.6 0.0 4e-05 23.5 0.0 1.6 2 0 0 2 2 2 1 Cytidylate kinase Rad17 PF03215.15 EAQ90877.1 - 7.5e-05 22.7 0.0 0.00021 21.3 0.0 1.7 2 0 0 2 2 2 1 Rad17 P-loop domain dNK PF01712.19 EAQ90877.1 - 9.9e-05 22.3 0.0 0.21 11.4 0.0 2.2 2 0 0 2 2 2 2 Deoxynucleoside kinase AAA_16 PF13191.6 EAQ90877.1 - 0.00012 22.5 0.0 0.00023 21.6 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EAQ90877.1 - 0.00039 20.7 0.0 0.00074 19.8 0.0 1.6 2 0 0 2 2 1 1 AAA domain RNA_helicase PF00910.22 EAQ90877.1 - 0.0029 18.0 0.0 0.0055 17.1 0.0 1.5 1 0 0 1 1 1 1 RNA helicase Cytidylate_kin2 PF13189.6 EAQ90877.1 - 0.0037 17.4 0.0 0.043 14.0 0.0 2.2 1 1 0 1 1 1 1 Cytidylate kinase-like family NACHT PF05729.12 EAQ90877.1 - 0.0062 16.5 0.0 0.01 15.8 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Thymidylate_kin PF02223.17 EAQ90877.1 - 0.0062 16.2 0.0 0.26 10.9 0.0 2.2 2 0 0 2 2 2 1 Thymidylate kinase APS_kinase PF01583.20 EAQ90877.1 - 0.007 16.3 0.0 0.0099 15.8 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase ATPase_2 PF01637.18 EAQ90877.1 - 0.008 16.1 0.0 0.016 15.2 0.0 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea ABC_tran PF00005.27 EAQ90877.1 - 0.008 16.7 0.0 0.016 15.7 0.0 1.5 1 0 0 1 1 1 1 ABC transporter Viral_helicase1 PF01443.18 EAQ90877.1 - 0.014 15.1 0.0 0.024 14.4 0.0 1.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_14 PF13173.6 EAQ90877.1 - 0.016 15.3 0.0 0.043 13.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 EAQ90877.1 - 0.017 15.0 0.0 0.087 12.7 0.0 1.9 2 0 0 2 2 2 0 NTPase Ploopntkinase1 PF18748.1 EAQ90877.1 - 0.02 14.4 0.0 5.1 6.6 0.0 2.4 2 1 0 2 2 2 0 P-loop Nucleotide Kinase1 AAA_24 PF13479.6 EAQ90877.1 - 0.021 14.6 0.1 0.035 13.8 0.1 1.6 1 1 0 1 1 1 0 AAA domain ADK PF00406.22 EAQ90877.1 - 0.022 14.9 0.1 1.9 8.6 0.0 2.1 2 0 0 2 2 2 0 Adenylate kinase AAA_5 PF07728.14 EAQ90877.1 - 0.024 14.6 0.0 0.043 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) CoaE PF01121.20 EAQ90877.1 - 0.035 13.8 0.0 0.09 12.4 0.0 1.7 2 0 0 2 2 2 0 Dephospho-CoA kinase AAA_28 PF13521.6 EAQ90877.1 - 0.035 14.3 0.0 0.064 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EAQ90877.1 - 0.038 13.3 0.0 0.073 12.3 0.0 1.9 1 1 0 1 1 1 0 Zeta toxin AAA_30 PF13604.6 EAQ90877.1 - 0.042 13.6 0.0 0.072 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain PRK PF00485.18 EAQ90877.1 - 0.043 13.6 0.0 0.082 12.6 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Mg_chelatase PF01078.21 EAQ90877.1 - 0.05 13.0 0.0 0.093 12.1 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_29 PF13555.6 EAQ90877.1 - 0.063 13.0 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain NB-ARC PF00931.22 EAQ90877.1 - 0.068 12.3 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_19 PF13245.6 EAQ90877.1 - 0.11 12.8 0.0 0.27 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EAQ90877.1 - 0.13 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Peptidase_M49 PF03571.15 EAQ90878.1 - 4.3e-234 778.0 0.0 5.1e-234 777.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M49 CdiA_C_tRNase PF18664.1 EAQ90878.1 - 0.0027 17.9 0.0 0.0078 16.4 0.0 1.7 1 0 0 1 1 1 1 CdiA C-terminal tRNase domain 2C_adapt PF08793.10 EAQ90878.1 - 0.086 13.0 0.3 0.18 12.0 0.3 1.5 1 0 0 1 1 1 0 2-cysteine adaptor domain zf-C2H2 PF00096.26 EAQ90879.1 - 4.1e-16 58.4 18.4 2.3e-05 24.6 0.7 5.8 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EAQ90879.1 - 5.1e-11 42.4 16.8 0.0003 21.3 0.6 5.9 5 0 0 5 5 5 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EAQ90879.1 - 2.7e-09 37.0 18.4 0.00029 21.1 3.1 4.9 3 1 0 3 3 3 3 Zinc-finger double domain zf-C2H2_6 PF13912.6 EAQ90879.1 - 2.3e-06 27.5 7.0 0.017 15.1 1.0 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EAQ90879.1 - 1e-05 25.7 6.9 0.059 13.7 0.1 3.7 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding Zn-C2H2_12 PF18112.1 EAQ90879.1 - 0.0066 16.9 5.1 0.83 10.2 0.1 4.0 3 0 0 3 3 3 1 Autophagy receptor zinc finger-C2H2 domain FOXP-CC PF16159.5 EAQ90879.1 - 0.0097 16.5 14.5 1.4 9.6 0.2 4.9 3 2 2 5 5 5 2 FOXP coiled-coil domain zf-C2HC_2 PF13913.6 EAQ90879.1 - 0.05 13.5 3.5 2 8.4 0.3 2.9 2 0 0 2 2 2 0 zinc-finger of a C2HC-type DEAD PF00270.29 EAQ90881.1 - 2.6e-51 173.9 0.0 1.5e-48 164.9 0.0 2.7 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_C PF00271.31 EAQ90881.1 - 2.2e-26 92.4 0.0 7.2e-26 90.7 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EAQ90881.1 - 0.0011 19.1 0.0 0.0028 17.7 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HMG_box PF00505.19 EAQ90882.1 - 1.5e-08 34.9 11.2 6.2e-06 26.5 2.8 3.5 2 1 2 4 4 4 2 HMG (high mobility group) box HMG_box_2 PF09011.10 EAQ90882.1 - 5.9e-08 33.2 18.9 1.9e-05 25.2 3.2 3.0 3 0 0 3 3 3 2 HMG-box domain Med3 PF11593.8 EAQ90882.1 - 0.12 11.6 12.4 0.15 11.2 12.4 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF2561 PF10812.8 EAQ90882.1 - 0.27 11.2 5.7 0.62 10.1 5.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2561) Dicty_REP PF05086.12 EAQ90882.1 - 2.9 5.8 9.4 3.6 5.4 9.4 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein RNA_pol_Rpc4 PF05132.14 EAQ90882.1 - 9 6.7 14.7 1.3 9.5 8.9 2.2 2 0 0 2 2 2 0 RNA polymerase III RPC4 3Beta_HSD PF01073.19 EAQ90884.1 - 1.4e-63 214.5 0.0 1.7e-63 214.3 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EAQ90884.1 - 3.7e-35 121.5 0.3 5.8e-35 120.9 0.1 1.3 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EAQ90884.1 - 2.6e-22 79.7 0.0 3.2e-18 66.2 0.0 2.1 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 EAQ90884.1 - 2.9e-14 52.9 0.0 3.8e-14 52.5 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 EAQ90884.1 - 1.2e-13 50.8 0.5 1.9e-10 40.4 0.1 2.1 1 1 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 EAQ90884.1 - 8.4e-11 42.1 0.0 1.2e-10 41.5 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 EAQ90884.1 - 2.6e-08 33.3 0.2 1.4e-07 31.0 0.3 2.1 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 EAQ90884.1 - 3.3e-05 24.2 0.1 0.00028 21.1 0.1 2.1 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain KR PF08659.10 EAQ90884.1 - 6.7e-05 22.9 2.3 0.00031 20.7 2.3 2.0 1 1 0 1 1 1 1 KR domain NmrA PF05368.13 EAQ90884.1 - 0.00026 20.6 0.0 0.00046 19.8 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family TrkA_N PF02254.18 EAQ90884.1 - 0.0016 18.7 0.0 0.0029 17.9 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_3 PF03447.16 EAQ90884.1 - 0.039 14.6 0.0 0.069 13.8 0.0 1.5 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain DapB_N PF01113.20 EAQ90884.1 - 0.071 13.2 0.0 0.2 11.8 0.0 1.8 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus RhoGAP PF00620.27 EAQ90885.1 - 2.1e-36 125.0 0.1 1.3e-35 122.5 0.1 2.2 2 0 0 2 2 2 1 RhoGAP domain LIM PF00412.22 EAQ90885.1 - 2.1e-30 104.7 37.5 3.2e-11 43.3 7.3 4.4 4 0 0 4 4 4 4 LIM domain Desulfoferrod_N PF06397.12 EAQ90885.1 - 0.11 12.1 0.8 0.57 9.8 0.1 2.6 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain DUF2417 PF10329.9 EAQ90886.1 - 7.8e-84 280.8 2.2 1e-83 280.4 2.2 1.1 1 0 0 1 1 1 1 Region of unknown function (DUF2417) Apt1 PF10351.9 EAQ90887.1 - 1.5 7.6 3.3 2.1 7.1 3.3 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain UQ_con PF00179.26 EAQ90888.1 - 7.6e-15 54.8 0.1 1.1e-08 34.8 0.0 3.1 3 0 0 3 3 3 2 Ubiquitin-conjugating enzyme Rep_fac_C PF08542.11 EAQ90889.1 - 1.1e-21 77.1 0.1 2e-21 76.2 0.1 1.5 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.29 EAQ90889.1 - 4.5e-16 59.5 0.0 1.1e-15 58.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 EAQ90889.1 - 1.7e-12 47.4 0.0 1.7e-10 40.9 0.0 2.4 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.15 EAQ90889.1 - 1.9e-09 37.7 0.0 5.7e-09 36.2 0.0 1.8 2 0 0 2 2 2 1 Rad17 P-loop domain RuvB_N PF05496.12 EAQ90889.1 - 1e-05 25.4 0.1 3.7e-05 23.5 0.0 2.0 3 0 0 3 3 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_assoc_2 PF16193.5 EAQ90889.1 - 1.8e-05 25.0 0.1 6.9e-05 23.1 0.1 2.0 1 0 0 1 1 1 1 AAA C-terminal domain AAA_22 PF13401.6 EAQ90889.1 - 3e-05 24.3 0.0 0.00093 19.5 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAQ90889.1 - 4.5e-05 23.4 0.1 0.00011 22.1 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EAQ90889.1 - 5.2e-05 23.7 0.0 0.0012 19.2 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain Mg_chelatase PF01078.21 EAQ90889.1 - 0.0001 21.8 0.0 0.0068 15.8 0.0 2.7 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 EAQ90889.1 - 0.00087 19.3 0.0 0.0018 18.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EAQ90889.1 - 0.0014 18.4 0.2 0.059 13.1 0.0 2.8 3 1 0 3 3 3 1 AAA domain AAA_19 PF13245.6 EAQ90889.1 - 0.002 18.5 0.1 0.018 15.4 0.0 2.4 2 1 0 2 2 2 1 AAA domain DUF815 PF05673.13 EAQ90889.1 - 0.0021 17.3 0.0 0.0032 16.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) DNA_pol3_delta PF06144.13 EAQ90889.1 - 0.0032 17.3 0.0 0.0064 16.3 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_7 PF12775.7 EAQ90889.1 - 0.0054 16.3 0.0 0.0089 15.6 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_5 PF07728.14 EAQ90889.1 - 0.006 16.6 0.1 0.036 14.1 0.0 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 EAQ90889.1 - 0.0064 16.2 0.0 0.022 14.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.9 EAQ90889.1 - 0.021 14.1 0.0 0.049 12.9 0.0 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_28 PF13521.6 EAQ90889.1 - 0.025 14.8 0.0 0.057 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 EAQ90889.1 - 0.027 14.5 0.0 0.15 12.1 0.0 2.0 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit AAA_18 PF13238.6 EAQ90889.1 - 0.037 14.6 0.0 0.11 13.1 0.0 1.8 1 1 0 1 1 1 0 AAA domain DUF4863 PF16155.5 EAQ90889.1 - 0.057 13.3 0.0 0.14 12.0 0.0 1.6 2 0 0 2 2 1 0 Domain of unknown function (DUF4863) TPM_phosphatase PF04536.14 EAQ90889.1 - 0.073 13.2 0.1 1.7 8.8 0.0 2.5 2 0 0 2 2 2 0 TPM domain AAA_3 PF07726.11 EAQ90889.1 - 0.083 12.7 0.0 0.52 10.2 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Peptidase_C47 PF05543.13 EAQ90889.1 - 0.1 12.2 0.1 0.76 9.3 0.0 2.3 3 0 0 3 3 2 0 Staphopain peptidase C47 RNA_helicase PF00910.22 EAQ90889.1 - 0.13 12.6 0.0 0.32 11.4 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Exonuc_VII_S PF02609.16 EAQ90890.1 - 0.069 13.2 0.6 0.27 11.3 0.6 2.1 1 0 0 1 1 1 0 Exonuclease VII small subunit Sec63 PF02889.16 EAQ90891.1 - 5.6e-166 550.0 0.8 1.1e-94 316.4 0.0 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 EAQ90891.1 - 3.3e-51 173.6 0.0 3.8e-28 98.4 0.1 3.2 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_PWI PF18149.1 EAQ90891.1 - 5.8e-35 119.8 0.5 1.8e-34 118.2 0.5 2.0 1 0 0 1 1 1 1 N-terminal helicase PWI domain ResIII PF04851.15 EAQ90891.1 - 4.7e-27 95.1 0.0 3.7e-14 53.1 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EAQ90891.1 - 9.4e-13 48.5 0.0 8.3e-09 35.8 0.0 3.8 2 1 0 2 2 2 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 EAQ90891.1 - 5.6e-07 29.9 0.1 0.026 14.8 0.1 3.6 2 1 0 2 2 2 2 AAA domain T2SSE PF00437.20 EAQ90891.1 - 1.8e-05 23.9 0.0 0.13 11.3 0.0 2.6 2 0 0 2 2 2 2 Type II/IV secretion system protein PhoH PF02562.16 EAQ90891.1 - 0.0098 15.4 0.0 2 7.8 0.0 2.6 2 0 0 2 2 2 1 PhoH-like protein DUF3335 PF11814.8 EAQ90891.1 - 0.012 15.1 1.7 5.1 6.5 0.0 3.4 3 0 0 3 3 3 0 Peptidase_C39 like family AAA_7 PF12775.7 EAQ90891.1 - 0.02 14.4 0.0 3.1 7.3 0.0 2.6 2 0 0 2 2 2 0 P-loop containing dynein motor region UvrD-helicase PF00580.21 EAQ90891.1 - 0.043 13.3 0.0 1.7 8.1 0.0 2.8 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain AAA_11 PF13086.6 EAQ90891.1 - 0.083 12.7 0.2 16 5.1 0.0 2.9 2 1 1 3 3 3 0 AAA domain Sigma54_activat PF00158.26 EAQ90891.1 - 0.12 12.1 0.0 2.1 8.0 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain TFIIE_alpha PF02002.17 EAQ90891.1 - 3.2 7.7 5.3 21 5.0 0.2 3.6 4 0 0 4 4 3 0 TFIIE alpha subunit PWWP PF00855.17 EAQ90892.1 - 5.5e-14 52.3 0.0 5.5e-14 52.3 0.0 3.1 3 0 0 3 3 3 1 PWWP domain Macoilin PF09726.9 EAQ90892.1 - 0.00091 17.9 15.7 0.004 15.8 0.0 2.0 1 1 1 2 2 2 1 Macoilin family Lin-8 PF03353.15 EAQ90892.1 - 0.49 9.9 24.8 0.024 14.2 10.4 2.2 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist ORC3_N PF07034.11 EAQ90893.1 - 2.3e-32 112.4 1.9 1.3e-30 106.7 1.9 2.2 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus ORC_WH_C PF18137.1 EAQ90893.1 - 1e-25 90.4 0.8 1.7e-13 50.8 0.0 3.0 2 1 1 3 3 3 2 Origin recognition complex winged helix C-terminal Sec66 PF09802.9 EAQ90894.1 - 5.2e-82 273.8 0.4 6.2e-82 273.5 0.4 1.1 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 DUF4456 PF14644.6 EAQ90894.1 - 0.0085 15.8 0.4 0.013 15.2 0.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4456) DUF3848 PF12959.7 EAQ90894.1 - 0.037 14.1 0.0 0.083 13.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3848) rRNA_processing PF08524.11 EAQ90894.1 - 0.07 13.2 4.9 0.12 12.4 4.9 1.4 1 0 0 1 1 1 0 rRNA processing FUSC PF04632.12 EAQ90894.1 - 0.11 11.0 1.6 0.13 10.8 1.6 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family NPL4 PF05021.15 EAQ90895.1 - 1.8e-140 467.6 0.0 2.3e-140 467.3 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.15 EAQ90895.1 - 9e-69 230.2 0.1 1.4e-68 229.6 0.1 1.3 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.8 EAQ90895.1 - 0.053 14.0 0.0 0.1 13.1 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 CPSase_L_D2 PF02786.17 EAQ90896.1 - 1.8e-111 370.7 0.1 4.7e-85 284.4 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 EAQ90896.1 - 1.1e-41 142.0 0.4 4.2e-41 140.1 0.2 2.2 2 0 0 2 2 2 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp PF02222.22 EAQ90896.1 - 6.1e-23 81.2 0.0 6e-11 42.2 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.13 EAQ90896.1 - 2.3e-20 73.0 1.2 5.6e-10 39.1 0.1 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 EAQ90896.1 - 8.7e-11 41.7 0.0 0.00073 19.3 0.0 3.0 3 0 0 3 3 3 2 ATP-grasp in the biosynthetic pathway with Ter operon GARS_A PF01071.19 EAQ90896.1 - 2.5e-07 30.7 0.2 0.011 15.5 0.1 2.8 2 0 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_3 PF02655.14 EAQ90896.1 - 8.1e-06 26.0 0.3 0.19 11.8 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain RimK PF08443.11 EAQ90896.1 - 2.6e-05 23.9 0.1 0.017 14.7 0.0 2.6 2 0 0 2 2 2 2 RimK-like ATP-grasp domain ATP-grasp_5 PF13549.6 EAQ90896.1 - 5.6e-05 22.7 0.1 0.019 14.4 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_4 PF13535.6 EAQ90896.1 - 0.0013 18.3 0.0 0.017 14.7 0.0 2.5 2 0 0 2 2 2 1 ATP-grasp domain Epimerase PF01370.21 EAQ90896.1 - 0.054 12.9 0.0 0.25 10.8 0.0 2.1 3 0 0 3 3 3 0 NAD dependent epimerase/dehydratase family MGS PF02142.22 EAQ90896.1 - 0.12 12.6 0.0 0.41 10.9 0.0 2.0 1 0 0 1 1 1 0 MGS-like domain DUF1746 PF08508.10 EAQ90897.1 - 1.2e-41 141.7 1.6 1.7e-41 141.2 1.6 1.2 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1746) RTC PF01137.21 EAQ90898.1 - 8.7e-30 103.6 0.3 1.1e-29 103.2 0.3 1.1 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 EAQ90898.1 - 3.2e-29 101.5 0.1 6.3e-29 100.5 0.1 1.5 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain PPR_2 PF13041.6 EAQ90899.1 - 4e-11 42.9 0.0 1.1e-05 25.5 0.0 5.8 6 0 0 6 6 6 1 PPR repeat family ATP13 PF12921.7 EAQ90899.1 - 0.0044 16.9 0.0 0.17 11.7 0.0 2.4 2 0 0 2 2 2 1 Mitochondrial ATPase expression PPR_3 PF13812.6 EAQ90899.1 - 0.0074 16.3 0.0 1.6 8.8 0.0 3.2 2 1 1 3 3 3 1 Pentatricopeptide repeat domain PPR PF01535.20 EAQ90899.1 - 0.0074 16.5 9.9 0.012 15.8 0.0 5.9 9 0 0 9 9 9 1 PPR repeat PPR_long PF17177.4 EAQ90899.1 - 0.016 14.6 0.0 0.11 11.8 0.0 2.2 2 1 0 2 2 2 0 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 EAQ90899.1 - 1.9 9.5 6.5 12 7.0 0.0 5.2 5 1 1 6 6 6 0 Tetratricopeptide repeat Diphthami_syn_2 PF01902.17 EAQ90900.1 - 2.4e-12 46.9 0.0 7.1e-06 25.7 0.0 3.8 3 1 0 3 3 3 3 Diphthamide synthase Ribonuc_L-PSP PF01042.21 EAQ90900.1 - 6.9e-09 35.8 0.8 5.5e-07 29.6 0.0 3.2 3 1 0 3 3 3 1 Endoribonuclease L-PSP zf-C2H2 PF00096.26 EAQ90901.1 - 7.7e-10 38.7 11.3 9e-07 29.0 0.3 3.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EAQ90901.1 - 1.8e-06 28.1 3.0 1.8e-06 28.1 3.0 3.0 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 EAQ90901.1 - 5.8e-05 23.6 9.2 0.0043 17.8 0.1 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.7 EAQ90901.1 - 0.00018 21.8 2.2 0.12 12.8 0.2 2.7 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EAQ90901.1 - 0.0019 18.5 2.6 0.37 11.1 0.9 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-BED PF02892.15 EAQ90901.1 - 0.49 10.5 3.7 0.22 11.6 0.8 2.0 1 1 1 2 2 2 0 BED zinc finger zf-C2H2_6 PF13912.6 EAQ90901.1 - 2 8.5 9.7 2.3 8.3 0.4 3.3 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_8 PF15909.5 EAQ90901.1 - 2.9 8.3 10.2 2.7 8.4 2.4 3.3 2 1 0 2 2 2 0 C2H2-type zinc ribbon Raftlin PF15250.6 EAQ90901.1 - 5.2 5.7 6.9 8 5.1 6.9 1.2 1 0 0 1 1 1 0 Raftlin DUF4187 PF13821.6 EAQ90905.1 - 4.2e-19 68.1 2.1 8.2e-19 67.1 1.0 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF4187) G-patch PF01585.23 EAQ90905.1 - 0.047 13.6 20.3 0.96 9.4 20.3 2.5 1 1 0 1 1 1 0 G-patch domain COesterase PF00135.28 EAQ90906.1 - 1.4e-61 208.9 0.0 2.1e-61 208.4 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EAQ90906.1 - 0.0066 16.3 0.1 0.011 15.7 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EAQ90906.1 - 0.018 14.5 0.1 0.024 14.1 0.1 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family zf-H2C2_2 PF13465.6 EAQ90907.1 - 6.2e-15 54.9 18.8 1.8e-08 34.4 2.0 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 EAQ90907.1 - 8.8e-09 35.4 24.2 0.0043 17.4 7.4 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EAQ90907.1 - 1.2e-07 31.9 21.2 0.038 14.8 6.1 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_9 PF16293.5 EAQ90907.1 - 1.9e-05 24.4 3.6 1 9.3 0.1 3.4 1 1 2 3 3 3 2 C2H2 type zinc-finger (1 copy) zf-C2H2_jaz PF12171.8 EAQ90907.1 - 0.0066 16.7 8.6 2.7 8.4 3.3 3.6 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 EAQ90907.1 - 0.0079 16.2 18.3 0.11 12.5 0.1 3.5 3 0 0 3 3 3 1 C2H2-type zinc finger zf-Di19 PF05605.12 EAQ90907.1 - 0.0089 16.3 12.9 0.04 14.2 7.4 2.4 1 1 1 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zinc_ribbon_9 PF14369.6 EAQ90907.1 - 0.015 15.6 3.6 11 6.3 0.1 3.3 3 0 0 3 3 3 0 zinc-ribbon zf-CHCC PF10276.9 EAQ90907.1 - 0.041 13.9 4.9 1.7 8.8 0.2 3.2 3 0 0 3 3 3 0 Zinc-finger domain PyrI_C PF02748.15 EAQ90907.1 - 0.17 11.8 0.2 0.41 10.6 0.2 1.6 1 0 0 1 1 1 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain DZR PF12773.7 EAQ90907.1 - 0.26 11.3 9.3 12 6.0 9.3 2.3 1 1 0 1 1 1 0 Double zinc ribbon Zn-ribbon_8 PF09723.10 EAQ90907.1 - 0.36 11.0 8.8 0.4 10.8 2.6 2.6 1 1 2 3 3 3 0 Zinc ribbon domain Prok-RING_1 PF14446.6 EAQ90907.1 - 0.42 10.6 3.5 24 5.0 0.2 3.2 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 GAGA PF09237.11 EAQ90907.1 - 0.51 10.2 11.5 0.073 12.9 1.1 3.6 2 1 2 4 4 4 0 GAGA factor Rad50_zn_hook PF04423.14 EAQ90907.1 - 0.64 9.9 13.5 0.13 12.2 2.5 2.8 1 1 2 3 3 3 0 Rad50 zinc hook motif zf-BED PF02892.15 EAQ90907.1 - 0.74 9.9 7.2 0.34 10.9 3.8 2.1 1 1 1 2 2 2 0 BED zinc finger TRAF6_Z2 PF18048.1 EAQ90907.1 - 1.2 9.3 6.1 7.1 6.8 0.1 3.4 3 0 0 3 3 3 0 TNF receptor-associated factor 6 zinc finger 2 Prok-RING_4 PF14447.6 EAQ90907.1 - 1.7 8.5 6.0 25 4.8 0.3 3.2 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 zf-C2H2_2 PF12756.7 EAQ90907.1 - 2.6 8.4 11.8 2.7 8.4 2.5 3.2 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) Zn_ribbon_SprT PF17283.2 EAQ90907.1 - 4.1 7.4 8.6 5.3 7.0 2.5 2.7 2 1 0 2 2 2 0 SprT-like zinc ribbon domain zinc-ribbons_6 PF07191.12 EAQ90907.1 - 4.2 7.4 5.9 24 5.0 5.8 2.1 1 1 0 1 1 1 0 zinc-ribbons DUF2225 PF09986.9 EAQ90907.1 - 7.9 6.1 8.8 2.6 7.7 1.0 2.8 1 1 2 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-UDP PF14569.6 EAQ90907.1 - 8 6.7 10.1 13 6.0 0.7 3.3 1 1 1 3 3 3 0 Zinc-binding RING-finger zf-C2HC_2 PF13913.6 EAQ90907.1 - 8.9 6.3 7.5 0.74 9.8 0.5 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Sortilin-Vps10 PF15902.5 EAQ90908.1 - 3.1e-297 985.4 14.3 2e-151 504.8 5.5 2.1 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 EAQ90908.1 - 1.3e-88 295.8 19.2 4.1e-46 157.4 10.6 2.6 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, C-terminal BNR PF02012.20 EAQ90908.1 - 4.8e-14 50.0 33.6 0.38 10.9 0.0 11.8 12 0 0 12 12 12 6 BNR/Asp-box repeat PSII_BNR PF14870.6 EAQ90908.1 - 9.4e-05 21.8 3.8 0.71 9.1 0.0 5.2 4 3 1 5 5 5 2 Photosynthesis system II assembly factor YCF48 BNR_6 PF15899.5 EAQ90908.1 - 0.00048 19.9 2.1 4.2 7.7 0.6 5.6 5 0 0 5 5 5 1 BNR-Asp box repeat CHB_HEX_C PF03174.13 EAQ90908.1 - 0.0038 17.2 2.9 8.2 6.5 0.1 5.3 4 1 1 5 5 5 1 Chitobiase/beta-hexosaminidase C-terminal domain preSET_CXC PF18264.1 EAQ90908.1 - 4.2 7.9 12.1 15 6.1 2.3 2.7 2 0 0 2 2 2 0 CXC domain DUF3884 PF13024.6 EAQ90910.1 - 0.087 12.4 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3884) LAM_C PF12544.8 EAQ90911.1 - 6.5e-05 23.1 0.0 0.00013 22.1 0.0 1.4 1 0 0 1 1 1 1 Lysine-2,3-aminomutase Radical_SAM PF04055.21 EAQ90911.1 - 0.0036 17.7 0.0 0.016 15.5 0.0 2.1 2 1 0 2 2 2 1 Radical SAM superfamily SHS2_Rpb7-N PF03876.17 EAQ90912.1 - 6.4e-15 55.3 0.0 1.2e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 EAQ90912.1 - 1.3e-09 38.2 0.0 2.2e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 S1 RNA binding domain DUF962 PF06127.11 EAQ90913.1 - 7.7e-14 51.5 0.5 9.9e-14 51.2 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF962) ATP_bind_1 PF03029.17 EAQ90915.1 - 2.6e-67 227.1 0.1 5.7e-66 222.7 0.1 2.0 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein RNA_helicase PF00910.22 EAQ90915.1 - 0.0002 21.7 0.0 0.00042 20.7 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_14 PF13173.6 EAQ90915.1 - 0.00021 21.3 0.0 0.00053 20.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain CLP1_P PF16575.5 EAQ90915.1 - 0.00038 20.3 0.0 0.0018 18.1 0.0 2.0 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_24 PF13479.6 EAQ90915.1 - 0.00052 19.8 0.0 0.00084 19.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EAQ90915.1 - 0.0014 18.6 0.3 0.079 12.9 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_18 PF13238.6 EAQ90915.1 - 0.0046 17.5 0.0 0.0098 16.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EAQ90915.1 - 0.0052 17.1 0.0 0.026 14.8 0.0 2.1 2 1 0 2 2 2 1 AAA domain Septin PF00735.18 EAQ90915.1 - 0.02 14.2 0.1 0.079 12.2 0.0 1.9 2 0 0 2 2 2 0 Septin ArsA_ATPase PF02374.15 EAQ90915.1 - 0.021 14.0 0.0 0.046 12.9 0.0 1.5 2 0 0 2 2 2 0 Anion-transporting ATPase AAA_7 PF12775.7 EAQ90915.1 - 0.022 14.3 0.0 0.037 13.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region CbiA PF01656.23 EAQ90915.1 - 0.026 14.6 0.0 0.034 14.2 0.0 1.3 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_16 PF13191.6 EAQ90915.1 - 0.026 14.9 0.0 0.049 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain GTP_EFTU PF00009.27 EAQ90915.1 - 0.03 13.9 0.1 1.8 8.1 0.0 2.6 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_33 PF13671.6 EAQ90915.1 - 0.041 14.0 0.0 0.075 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 EAQ90915.1 - 0.045 13.4 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain MMR_HSR1 PF01926.23 EAQ90915.1 - 0.046 13.8 0.0 0.27 11.3 0.0 2.1 2 1 0 2 2 2 0 50S ribosome-binding GTPase NTPase_1 PF03266.15 EAQ90915.1 - 0.052 13.5 0.3 0.6 10.0 0.0 2.5 3 0 0 3 3 3 0 NTPase PduV-EutP PF10662.9 EAQ90915.1 - 0.056 13.2 0.1 0.33 10.7 0.0 2.1 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation AAA_5 PF07728.14 EAQ90915.1 - 0.062 13.3 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 EAQ90915.1 - 0.087 12.7 0.1 0.15 12.0 0.1 1.5 1 1 0 1 1 1 0 NACHT domain AAA PF00004.29 EAQ90915.1 - 0.099 13.1 0.0 0.19 12.2 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_31 PF13614.6 EAQ90915.1 - 0.1 12.5 0.2 14 5.5 0.1 2.5 2 1 1 3 3 3 0 AAA domain ATPase_2 PF01637.18 EAQ90915.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.6 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea PPV_E1_C PF00519.17 EAQ90915.1 - 0.12 11.2 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase AAA_29 PF13555.6 EAQ90915.1 - 0.14 11.9 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain PHD PF00628.29 EAQ90916.1 - 6e-08 32.5 5.4 9.5e-08 31.8 5.4 1.3 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 EAQ90916.1 - 0.0042 16.6 3.1 0.0071 15.9 3.1 1.4 1 0 0 1 1 1 1 PHD-finger C1_1 PF00130.22 EAQ90916.1 - 2.7 8.0 5.6 1 9.3 3.2 1.5 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Iso_dh PF00180.20 EAQ90917.1 - 3.9e-104 348.5 0.0 4.5e-86 289.1 0.0 2.0 1 1 1 2 2 2 2 Isocitrate/isopropylmalate dehydrogenase AMPK1_CBM PF16561.5 EAQ90919.1 - 1.7e-06 28.1 0.1 3e-06 27.4 0.1 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase Iwr1 PF08574.10 EAQ90920.1 - 9.8e-16 58.5 8.9 9.8e-16 58.5 8.9 2.6 2 0 0 2 2 2 1 Transcription factor Iwr1 His_Phos_1 PF00300.22 EAQ90923.1 - 3.7e-18 65.9 0.0 1.1e-17 64.4 0.0 1.7 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) DUF5102 PF17104.5 EAQ90924.1 - 0.13 12.2 3.6 0.21 11.6 3.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF5102) RabGAP-TBC PF00566.18 EAQ90925.1 - 1.5e-06 28.1 0.0 2.2e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PBD PF00786.28 EAQ90927.1 - 0.02 15.3 0.1 0.062 13.7 0.1 1.9 1 0 0 1 1 1 0 P21-Rho-binding domain Histone PF00125.24 EAQ90928.1 - 3.2e-30 105.2 1.1 3.5e-30 105.0 1.1 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 EAQ90928.1 - 3.6e-05 23.8 0.0 4.2e-05 23.6 0.0 1.0 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 EAQ90928.1 - 4.5e-05 23.7 0.0 5.3e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 EAQ90928.1 - 0.0078 16.5 0.1 0.0087 16.3 0.1 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 EAQ90928.1 - 0.042 13.9 0.0 0.053 13.6 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit adh_short PF00106.25 EAQ90929.1 - 4.4e-20 72.0 0.0 6.1e-20 71.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EAQ90929.1 - 1.1e-12 48.0 0.0 1.6e-12 47.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EAQ90929.1 - 2.8e-07 30.6 0.0 4.2e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EAQ90929.1 - 3.2e-05 23.5 0.0 4.8e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EAQ90929.1 - 0.039 13.0 0.0 0.078 12.0 0.0 1.5 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EAQ90929.1 - 0.065 12.6 0.1 0.22 10.9 0.1 1.7 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EAQ90929.1 - 0.15 12.0 0.1 0.24 11.2 0.1 1.3 1 0 0 1 1 1 0 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 EAQ90929.1 - 0.31 11.3 0.6 0.84 9.9 0.6 1.6 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Bromodomain PF00439.25 EAQ90930.1 - 9.8e-24 83.2 0.2 1.9e-23 82.4 0.2 1.4 1 0 0 1 1 1 1 Bromodomain Acetyltransf_10 PF13673.7 EAQ90930.1 - 2.6e-07 30.6 0.1 4.6e-07 29.8 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EAQ90930.1 - 3.4e-07 30.5 0.0 6.6e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EAQ90930.1 - 0.00027 21.3 0.2 0.00056 20.3 0.2 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain EamA PF00892.20 EAQ90931.1 - 0.011 15.9 6.8 0.011 15.9 6.8 2.5 2 1 0 2 2 2 0 EamA-like transporter family PHO4 PF01384.20 EAQ90931.1 - 1.9 7.4 15.9 0.077 12.0 7.4 2.2 1 1 1 2 2 2 0 Phosphate transporter family CPBP PF02517.16 EAQ90932.1 - 1.8e-15 57.1 5.0 1.8e-15 57.1 5.0 2.8 3 1 0 3 3 3 1 CPBP intramembrane metalloprotease DUF1970 PF09301.10 EAQ90933.1 - 3.8 7.8 6.0 14 6.0 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1970) MBOAT PF03062.19 EAQ90934.1 - 6.2e-60 203.4 2.0 6.2e-60 203.4 2.0 1.7 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family MMM1 PF10296.9 EAQ90936.1 - 2.9e-112 375.0 1.9 2.5e-65 220.7 0.0 3.1 1 1 1 2 2 2 2 Maintenance of mitochondrial morphology protein 1 Sec1 PF00995.23 EAQ90937.1 - 2e-133 446.6 0.0 2.3e-133 446.4 0.0 1.0 1 0 0 1 1 1 1 Sec1 family GSH_synth_ATP PF03917.17 EAQ90938.1 - 8.5e-72 242.0 0.0 1.1e-71 241.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 EAQ90938.1 - 1.2e-31 109.2 0.0 2.4e-31 108.2 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic glutathione synthase SNF2_N PF00176.23 EAQ90939.1 - 1.3e-33 116.2 0.5 1.8e-29 102.6 0.0 2.3 1 1 1 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 EAQ90939.1 - 2.5e-20 72.8 0.2 5.6e-20 71.7 0.2 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EAQ90939.1 - 5.8e-05 23.2 0.0 0.00017 21.6 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EAQ90939.1 - 0.00039 19.7 0.1 0.00087 18.6 0.1 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase SWI2_SNF2 PF18766.1 EAQ90939.1 - 0.00094 18.9 0.2 0.038 13.6 0.0 2.4 2 0 0 2 2 2 1 SWI2/SNF2 ATPase HDA2-3 PF11496.8 EAQ90939.1 - 0.066 12.4 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 TFIIS_M PF07500.14 EAQ90939.1 - 0.083 13.4 0.2 0.083 13.4 0.2 2.2 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS), central domain Aminotran_1_2 PF00155.21 EAQ90940.1 - 5.5e-26 91.6 0.3 3e-23 82.6 0.0 3.2 2 1 2 4 4 4 2 Aminotransferase class I and II Aminotran_5 PF00266.19 EAQ90940.1 - 0.0024 16.9 0.0 0.0037 16.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DUF3405 PF11885.8 EAQ90940.1 - 0.19 10.3 0.2 0.31 9.6 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3405) Zn_clus PF00172.18 EAQ90941.1 - 0.014 15.6 13.1 0.022 14.9 13.1 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain AAA_11 PF13086.6 EAQ90943.1 - 0.00097 19.0 0.1 0.36 10.6 0.0 2.2 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.6 EAQ90943.1 - 0.024 14.3 0.0 8.4 6.1 0.2 2.3 1 1 1 2 2 2 0 AAA domain AAA_22 PF13401.6 EAQ90943.1 - 0.065 13.5 0.2 0.72 10.1 0.1 2.2 1 1 1 2 2 2 0 AAA domain AAA_12 PF13087.6 EAQ90943.1 - 0.096 12.3 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 EAQ90943.1 - 0.14 12.5 0.1 4.9 7.5 0.2 2.3 1 1 1 2 2 2 0 AAA domain Lyase_1 PF00206.20 EAQ90944.1 - 1e-16 61.3 0.1 3.4e-16 59.5 0.1 1.8 1 1 0 1 1 1 1 Lyase ADSL_C PF10397.9 EAQ90944.1 - 4e-14 52.9 0.0 1.2e-13 51.4 0.0 1.9 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus TraH PF06122.11 EAQ90944.1 - 0.099 11.9 0.1 0.17 11.2 0.1 1.3 1 0 0 1 1 1 0 Conjugative relaxosome accessory transposon protein Glyco_hydro_59 PF02057.15 EAQ90945.1 - 6.5e-14 51.9 0.4 1e-13 51.2 0.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 Glyco_hydr_30_2 PF14587.6 EAQ90945.1 - 2.4e-13 50.4 4.2 1.3e-12 48.0 0.1 2.2 2 0 0 2 2 2 1 O-Glycosyl hydrolase family 30 Glyco_hydro_30C PF17189.4 EAQ90945.1 - 1.9e-10 40.8 8.0 2.7e-09 37.1 8.0 2.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain Glyco_hydro_30 PF02055.16 EAQ90945.1 - 6.3e-10 38.6 0.1 1e-09 37.8 0.1 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain TMP-TENI PF02581.17 EAQ90946.1 - 8.4e-57 191.4 2.2 1.3e-56 190.7 2.2 1.3 1 0 0 1 1 1 1 Thiamine monophosphate synthase HK PF02110.15 EAQ90946.1 - 3.2e-56 190.5 6.0 6.8e-29 101.0 0.1 2.8 2 1 1 3 3 3 2 Hydroxyethylthiazole kinase family Carb_kinase PF01256.17 EAQ90946.1 - 2.4e-05 23.9 0.1 5.6e-05 22.7 0.1 1.5 1 0 0 1 1 1 1 Carbohydrate kinase Isochorismatase PF00857.20 EAQ90947.1 - 4.4e-26 92.1 0.0 6.5e-26 91.6 0.0 1.3 1 0 0 1 1 1 1 Isochorismatase family PhrC_PhrF PF11131.8 EAQ90948.1 - 0.71 9.5 2.2 1.7 8.3 2.2 1.6 1 0 0 1 1 1 0 Rap-phr extracellular signalling Lipase_GDSL_2 PF13472.6 EAQ90949.1 - 2.8e-22 80.0 0.0 3.8e-22 79.5 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EAQ90949.1 - 1.6e-13 51.1 0.0 3e-13 50.2 0.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 EAQ90949.1 - 0.047 13.8 0.1 0.13 12.4 0.0 1.6 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family LysM PF01476.20 EAQ90950.1 - 0.013 15.5 0.0 0.023 14.7 0.0 1.3 1 0 0 1 1 1 0 LysM domain MITF_TFEB_C_3_N PF15951.5 EAQ90950.1 - 0.027 15.1 4.7 0.06 14.0 4.7 1.5 1 0 0 1 1 1 0 MITF/TFEB/TFEC/TFE3 N-terminus Pro-rich PF15240.6 EAQ90950.1 - 0.04 14.2 23.5 0.067 13.5 23.5 1.3 1 0 0 1 1 1 0 Proline-rich MGC-24 PF05283.11 EAQ90950.1 - 8.3 6.9 14.0 12 6.3 4.5 2.3 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin MMS1_N PF10433.9 EAQ90951.1 - 8.4e-154 512.8 0.0 2e-153 511.6 0.0 1.6 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 EAQ90951.1 - 8.8e-101 337.4 0.0 5.2e-100 334.9 0.0 2.2 3 0 0 3 3 3 1 CPSF A subunit region UBM PF14377.6 EAQ90951.1 - 0.078 12.5 0.9 0.4 10.2 0.1 2.4 2 0 0 2 2 2 0 Ubiquitin binding region zf-Mss51 PF13824.6 EAQ90952.1 - 5.5e-29 100.0 7.6 1.1e-28 99.0 7.6 1.6 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.18 EAQ90952.1 - 0.018 15.1 2.4 0.018 15.1 2.4 2.0 2 0 0 2 2 2 0 MYND finger PXA PF02194.15 EAQ90953.1 - 1.3e-46 158.9 0.5 1.8e-46 158.4 0.5 1.2 1 0 0 1 1 1 1 PXA domain UL45 PF05473.12 EAQ90953.1 - 0.15 11.7 0.0 0.32 10.6 0.0 1.4 1 0 0 1 1 1 0 UL45 protein, carbohydrate-binding C-type lectin-like HTH_Tnp_Tc5 PF03221.16 EAQ90955.1 - 9.2e-11 41.6 0.0 2.8e-10 40.1 0.0 1.8 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 EAQ90955.1 - 4.5e-07 29.4 0.0 8.1e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain MarR PF01047.22 EAQ90955.1 - 0.0081 16.1 0.1 0.047 13.6 0.0 2.2 2 0 0 2 2 2 1 MarR family HTH_Tnp_4 PF13613.6 EAQ90955.1 - 0.024 14.4 0.0 0.048 13.4 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease MarR_2 PF12802.7 EAQ90955.1 - 0.08 12.8 0.1 0.38 10.7 0.0 2.2 2 0 0 2 2 2 0 MarR family MqsA_antitoxin PF15731.5 EAQ90955.1 - 0.081 13.0 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA LacI PF00356.21 EAQ90955.1 - 0.15 11.9 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family MMR_HSR1_Xtn PF16897.5 EAQ90958.1 - 4.6e-41 139.1 0.8 3.1e-40 136.5 0.5 2.0 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 EAQ90958.1 - 4.8e-21 75.0 0.0 3.6e-20 72.1 0.0 2.0 1 1 1 2 2 2 1 50S ribosome-binding GTPase TGS PF02824.21 EAQ90958.1 - 8.4e-19 67.4 0.0 1.7e-18 66.4 0.0 1.5 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 EAQ90958.1 - 8.5e-09 35.1 0.0 3.7e-08 33.1 0.0 1.9 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 EAQ90958.1 - 0.00047 19.7 0.1 12 5.3 0.0 3.6 2 2 2 4 4 4 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 EAQ90958.1 - 0.00077 19.6 0.1 0.15 12.1 0.0 2.3 1 1 1 2 2 2 1 Dynamin family MeaB PF03308.16 EAQ90958.1 - 0.0047 15.9 0.3 0.02 13.9 0.1 1.9 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB RsgA_GTPase PF03193.16 EAQ90958.1 - 0.06 13.2 0.4 4.3 7.2 0.1 2.6 2 0 0 2 2 2 0 RsgA GTPase Arf PF00025.21 EAQ90958.1 - 0.068 12.6 0.1 8.5 5.8 0.0 2.2 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_22 PF13401.6 EAQ90958.1 - 0.082 13.2 0.0 1.4 9.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 EAQ90958.1 - 0.098 12.9 0.1 2.1 8.6 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Ank_2 PF12796.7 EAQ90960.1 - 3.3e-28 98.1 0.5 2.9e-14 53.4 0.2 3.1 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAQ90960.1 - 1.9e-17 63.4 0.0 3.5e-05 24.3 0.1 4.9 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAQ90960.1 - 3.9e-13 49.4 0.9 1e-06 28.9 0.3 4.0 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAQ90960.1 - 6.1e-12 44.6 0.1 0.0014 19.0 0.1 5.3 5 0 0 5 5 5 2 Ankyrin repeat Ank PF00023.30 EAQ90960.1 - 8.8e-12 44.9 1.6 0.00015 22.1 0.2 4.6 4 0 0 4 4 4 2 Ankyrin repeat Steroid_dh PF02544.16 EAQ90961.1 - 7.3e-13 48.7 0.9 1.4e-12 47.8 0.9 1.5 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase PrgI PF12666.7 EAQ90961.1 - 0.67 10.7 3.5 0.74 10.6 0.1 2.7 3 0 0 3 3 3 0 PrgI family protein ATP-synt_DE_N PF02823.16 EAQ90962.1 - 2.1e-16 59.6 0.0 3.2e-16 59.0 0.0 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain DUF2457 PF10446.9 EAQ90963.1 - 2.5e-172 574.2 51.2 2.5e-172 574.2 51.2 3.8 2 2 0 2 2 2 1 Protein of unknown function (DUF2457) Nop14 PF04147.12 EAQ90963.1 - 0.017 13.3 29.8 0.036 12.3 29.8 1.5 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 EAQ90963.1 - 0.28 10.6 36.3 0.72 9.2 36.3 1.7 1 0 0 1 1 1 0 SDA1 TFIIA PF03153.13 EAQ90963.1 - 0.88 9.5 23.8 0.17 11.9 19.3 1.8 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Arf PF00025.21 EAQ90964.1 - 2.1e-65 219.4 0.0 2.5e-65 219.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 EAQ90964.1 - 1.1e-10 41.2 0.1 4.9e-07 29.2 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 EAQ90964.1 - 1.3e-07 31.8 0.0 4.2e-07 30.2 0.0 1.7 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EAQ90964.1 - 2.3e-07 30.6 0.0 3e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 EAQ90964.1 - 2.4e-07 30.4 0.0 3e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EAQ90964.1 - 3.9e-07 30.1 0.0 5.2e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EAQ90964.1 - 7.9e-06 25.4 0.0 9.3e-06 25.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EAQ90964.1 - 0.00069 19.2 0.1 0.027 14.0 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain CENP-M PF11111.8 EAQ90964.1 - 0.13 11.5 0.0 0.37 10.0 0.0 1.6 2 0 0 2 2 2 0 Centromere protein M (CENP-M) DUF3336 PF11815.8 EAQ90965.1 - 4.8e-50 168.9 0.4 7.3e-50 168.3 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 EAQ90965.1 - 4.6e-18 66.1 0.5 4e-17 63.1 0.0 2.6 2 1 0 2 2 2 1 Patatin-like phospholipase DUF616 PF04765.13 EAQ90965.1 - 0.11 11.8 0.0 0.16 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF616) Mucin-like PF16058.5 EAQ90966.1 - 0.35 11.0 12.4 1.9 8.6 11.9 2.1 1 1 1 2 2 2 0 Mucin-like GRA6 PF05084.13 EAQ90966.1 - 0.79 9.6 4.4 1.2 9.1 4.4 1.3 1 0 0 1 1 1 0 Granule antigen protein (GRA6) Polysacc_deac_1 PF01522.21 EAQ90968.1 - 2.5e-28 98.5 0.0 4.1e-28 97.8 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.19 EAQ90968.1 - 2.3e-07 31.2 63.4 1.1e-05 25.8 12.5 4.0 4 0 0 4 4 4 2 Chitin recognition protein Aldedh PF00171.22 EAQ90971.1 - 7.7e-183 608.2 0.2 8.7e-183 608.0 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 EAQ90971.1 - 0.00028 20.4 0.1 0.0098 15.4 0.0 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF1487) LMBR1 PF04791.16 EAQ90972.1 - 1.3e-115 387.3 4.6 1.5e-115 387.1 4.6 1.0 1 0 0 1 1 1 1 LMBR1-like membrane protein SGL PF08450.12 EAQ90974.1 - 2.8e-63 213.8 0.0 3.8e-63 213.3 0.0 1.2 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region PD40 PF07676.12 EAQ90974.1 - 0.01 15.8 0.1 0.026 14.5 0.1 1.7 1 0 0 1 1 1 1 WD40-like Beta Propeller Repeat DUF5008 PF16400.5 EAQ90974.1 - 0.15 12.2 0.0 0.3 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5008) Reg_prop PF07494.11 EAQ90974.1 - 0.19 12.0 0.3 1.7 9.1 0.0 2.7 2 0 0 2 2 2 0 Two component regulator propeller bZIP_2 PF07716.15 EAQ90977.1 - 1.5e-05 24.9 22.2 1.5e-05 24.9 22.2 2.0 1 1 1 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 EAQ90977.1 - 0.0017 18.4 20.7 0.0073 16.4 19.6 2.1 1 1 1 2 2 2 2 bZIP transcription factor DUF3450 PF11932.8 EAQ90977.1 - 0.064 12.6 4.2 0.093 12.0 4.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) LCD1 PF09798.9 EAQ90977.1 - 0.19 10.2 2.3 0.26 9.7 2.3 1.0 1 0 0 1 1 1 0 DNA damage checkpoint protein TMCO5 PF14992.6 EAQ90977.1 - 0.24 11.0 4.4 0.34 10.4 4.4 1.1 1 0 0 1 1 1 0 TMCO5 family APG6_N PF17675.1 EAQ90977.1 - 0.67 10.5 16.0 1 9.9 16.0 1.1 1 0 0 1 1 1 0 Apg6 coiled-coil region CENP-H PF05837.12 EAQ90977.1 - 0.91 10.0 7.6 1.5 9.3 7.6 1.3 1 0 0 1 1 1 0 Centromere protein H (CENP-H) DUF4140 PF13600.6 EAQ90977.1 - 2.4 8.7 6.1 5.6 7.5 6.1 1.6 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) IFT20 PF14931.6 EAQ90977.1 - 3.4 7.9 11.4 5.4 7.2 11.4 1.2 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 Katanin_con80 PF13925.6 EAQ90977.1 - 4.6 7.3 5.5 6.9 6.7 5.5 1.2 1 0 0 1 1 1 0 con80 domain of Katanin Coiled PF05710.12 EAQ90979.1 - 0.015 16.1 5.7 0.018 15.8 5.7 1.3 1 1 0 1 1 1 0 Coiled coil CRIM PF16978.5 EAQ90980.1 - 8.1e-47 158.9 0.0 1.6e-46 158.0 0.0 1.5 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), middle CRIM domain SIN1_PH PF16979.5 EAQ90980.1 - 1e-32 112.7 0.0 1.8e-32 111.9 0.0 1.4 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology PRCC PF10253.9 EAQ90981.1 - 2e-29 103.9 10.0 2e-29 103.9 10.0 2.5 2 0 0 2 2 1 1 Mitotic checkpoint regulator, MAD2B-interacting TPR_1 PF00515.28 EAQ90981.1 - 5.5e-19 67.1 13.4 0.00059 19.5 0.0 7.6 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.6 EAQ90981.1 - 4.1e-16 57.8 12.3 0.0019 18.3 0.0 7.5 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_2 PF07719.17 EAQ90981.1 - 4.7e-14 51.3 29.8 0.08 13.1 0.1 8.8 10 0 0 10 10 8 5 Tetratricopeptide repeat TPR_14 PF13428.6 EAQ90981.1 - 3.4e-13 49.2 26.5 0.012 16.4 0.3 8.1 7 1 1 8 8 7 5 Tetratricopeptide repeat ANAPC8 PF04049.13 EAQ90981.1 - 1.3e-12 47.9 0.6 2.5e-12 47.0 0.0 1.8 2 0 0 2 2 1 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_11 PF13414.6 EAQ90981.1 - 2.9e-08 33.3 10.2 0.0051 16.5 0.6 5.8 5 1 1 6 6 6 2 TPR repeat TPR_12 PF13424.6 EAQ90981.1 - 8.3e-07 29.2 24.8 0.005 17.1 2.7 6.2 5 2 1 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 EAQ90981.1 - 1.3e-06 28.0 10.3 0.64 10.2 0.2 5.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 EAQ90981.1 - 6.5e-05 23.5 0.9 6.5e-05 23.5 0.9 5.4 4 2 1 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 EAQ90981.1 - 8.6e-05 23.0 23.6 0.12 12.9 0.7 5.8 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_15 PF13429.6 EAQ90981.1 - 0.00091 18.5 5.7 0.0021 17.3 5.7 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.6 EAQ90981.1 - 0.0014 18.8 6.7 59 4.4 0.2 6.2 6 0 0 6 6 6 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EAQ90981.1 - 0.88 9.8 18.9 1.8 8.8 0.6 6.1 4 1 3 7 7 7 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 EAQ90981.1 - 5.8 7.1 17.0 0.9 9.7 0.5 4.5 3 1 1 4 4 4 0 Tetratricopeptide repeat CD99L2 PF12301.8 EAQ90983.1 - 0.3 11.4 1.3 14 5.9 0.1 2.4 2 0 0 2 2 2 0 CD99 antigen like protein 2 DUF3517 PF12030.8 EAQ90984.1 - 1.8e-88 296.7 0.0 1e-45 156.1 0.0 2.5 1 1 1 2 2 2 2 Domain of unknown function (DUF3517) UCH PF00443.29 EAQ90984.1 - 1.7e-33 116.2 0.1 3.9e-33 115.0 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EAQ90984.1 - 1.2e-11 44.8 1.8 4.2e-05 23.3 0.0 2.5 1 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase RNase_P_pop3 PF08228.11 EAQ90985.1 - 7.5e-09 35.8 0.0 1.9e-08 34.5 0.0 1.7 2 1 0 2 2 2 1 RNase P subunit Pop3 Pyr_redox_2 PF07992.14 EAQ90986.1 - 4.4e-35 121.3 0.0 5.1e-30 104.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EAQ90986.1 - 3.5e-08 33.9 0.0 9.7e-08 32.5 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EAQ90986.1 - 0.034 13.4 0.0 1 8.5 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Anillin PF08174.11 EAQ90987.1 - 1.7e-14 54.4 0.0 4.4e-14 53.1 0.0 1.7 1 0 0 1 1 1 1 Cell division protein anillin PH PF00169.29 EAQ90987.1 - 2e-06 28.2 0.0 6.3e-06 26.6 0.0 1.9 1 0 0 1 1 1 1 PH domain DUF697 PF05128.12 EAQ90987.1 - 0.11 12.2 0.6 0.18 11.5 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF697) His_biosynth PF00977.21 EAQ90988.1 - 4e-34 118.1 0.0 4.9e-34 117.8 0.0 1.1 1 0 0 1 1 1 1 Histidine biosynthesis protein Ribul_P_3_epim PF00834.19 EAQ90988.1 - 0.14 11.6 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family DUF4602 PF15375.6 EAQ90989.1 - 5.6e-06 26.7 15.2 6.5e-05 23.3 15.2 2.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4602) DNA_pol_phi PF04931.13 EAQ90989.1 - 0.36 8.9 8.7 0.49 8.4 8.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi AJAP1_PANP_C PF15298.6 EAQ90989.1 - 2.9 8.1 8.4 0.94 9.7 4.6 2.1 1 1 1 2 2 2 0 AJAP1/PANP C-terminus TFIIE-A_C PF11521.8 EAQ90989.1 - 4 7.8 9.3 10 6.5 9.3 1.7 1 0 0 1 1 1 0 C-terminal general transcription factor TFIIE alpha Nop14 PF04147.12 EAQ90989.1 - 5.6 5.0 13.1 8 4.5 13.1 1.2 1 0 0 1 1 1 0 Nop14-like family eIF-3c_N PF05470.12 EAQ90989.1 - 9.9 4.3 6.5 15 3.8 6.5 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus STE PF02200.16 EAQ90990.1 - 1.7e-56 189.4 0.1 2.8e-56 188.6 0.1 1.4 1 0 0 1 1 1 1 STE like transcription factor zf-C2H2 PF00096.26 EAQ90990.1 - 0.0013 19.0 4.2 0.0041 17.5 4.2 1.9 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EAQ90990.1 - 0.027 15.3 2.4 0.069 14.0 2.4 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger CBF PF03914.17 EAQ90992.1 - 4.8e-27 95.1 0.2 1.4e-26 93.5 0.0 1.8 2 0 0 2 2 2 1 CBF/Mak21 family NOC3p PF07540.11 EAQ90992.1 - 1.6e-26 92.6 0.1 7.1e-26 90.5 0.0 2.2 2 0 0 2 2 2 1 Nucleolar complex-associated protein BP28CT PF08146.12 EAQ90993.1 - 4.2e-43 146.9 0.0 1.4e-42 145.2 0.0 2.0 1 0 0 1 1 1 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.8 EAQ90993.1 - 2.7e-25 89.0 0.2 2.7e-25 89.0 0.2 6.2 6 1 1 7 7 7 1 U3 small nucleolar RNA-associated protein 10 HEAT PF02985.22 EAQ90993.1 - 0.014 15.6 11.6 0.027 14.7 0.2 5.7 6 0 0 6 6 6 0 HEAT repeat Pex26 PF07163.12 EAQ90994.1 - 0.06 12.7 0.3 0.06 12.7 0.3 2.2 2 1 1 3 3 3 0 Pex26 protein GAGA_bind PF06217.12 EAQ90994.1 - 0.6 10.3 4.5 0.84 9.9 4.5 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family RR_TM4-6 PF06459.12 EAQ90994.1 - 2.5 7.9 8.5 3.7 7.3 8.5 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.14 EAQ90994.1 - 3 6.0 13.3 4.1 5.6 13.3 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF1451 PF07295.11 EAQ90994.1 - 3.9 7.5 11.1 0.93 9.5 7.4 1.8 1 1 0 1 1 1 0 Zinc-ribbon containing domain PHF5 PF03660.14 EAQ90995.1 - 5e-52 174.5 10.5 5.7e-52 174.3 10.5 1.0 1 0 0 1 1 1 1 PHF5-like protein PolC_DP2 PF03833.13 EAQ90995.1 - 0.7 7.7 7.7 0.73 7.6 7.7 1.2 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DZR PF12773.7 EAQ90995.1 - 3.1 7.9 16.0 6.1 6.9 2.1 3.0 1 1 1 2 2 2 0 Double zinc ribbon Pinin_SDK_memA PF04696.13 EAQ90996.1 - 2.2e-14 53.6 30.8 7.4e-14 51.9 19.6 2.8 2 1 1 3 3 3 2 pinin/SDK/memA/ protein conserved region MAS20 PF02064.15 EAQ90996.1 - 1.8 8.6 7.1 3.6 7.7 7.1 1.5 1 0 0 1 1 1 0 MAS20 protein import receptor Abhydrolase_1 PF00561.20 EAQ90997.1 - 2.1e-21 76.7 0.0 2.3e-20 73.4 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EAQ90997.1 - 1.9e-17 64.6 1.4 2.5e-17 64.2 1.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EAQ90997.1 - 3.7e-14 52.6 0.0 1.6e-12 47.2 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 EAQ90997.1 - 0.0098 15.7 0.0 0.023 14.4 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S28 PF05577.12 EAQ90997.1 - 0.032 13.0 0.0 0.051 12.4 0.0 1.2 1 0 0 1 1 1 0 Serine carboxypeptidase S28 Abhydrolase_4 PF08386.10 EAQ90997.1 - 0.057 13.5 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein Chlorophyllase PF07224.11 EAQ90997.1 - 0.062 12.3 0.0 0.083 11.9 0.0 1.1 1 0 0 1 1 1 0 Chlorophyllase DLH PF01738.18 EAQ90997.1 - 0.086 12.4 0.0 0.32 10.5 0.0 1.8 2 0 0 2 2 2 0 Dienelactone hydrolase family Cript PF10235.9 EAQ90998.1 - 3.3e-20 72.4 9.2 3.3e-20 72.4 9.2 1.4 2 0 0 2 2 2 1 Microtubule-associated protein CRIPT DZR PF12773.7 EAQ90998.1 - 0.0035 17.3 6.4 0.0035 17.3 6.4 2.4 2 1 0 2 2 2 1 Double zinc ribbon zinc_ribbon_15 PF17032.5 EAQ90998.1 - 0.094 13.5 12.1 0.21 12.4 8.5 2.7 2 1 0 2 2 2 0 zinc-ribbon family CTX_RstB PF07459.11 EAQ90998.1 - 0.12 12.7 0.2 0.19 12.0 0.2 1.4 1 0 0 1 1 1 0 CTX phage RstB protein PolC_DP2 PF03833.13 EAQ90998.1 - 0.73 7.6 4.6 0.63 7.8 4.6 1.2 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-RING_5 PF14634.6 EAQ90998.1 - 0.99 9.4 11.7 0.09 12.8 3.9 2.6 3 0 0 3 3 3 0 zinc-RING finger domain zinc_ribbon_2 PF13240.6 EAQ90998.1 - 2.1 8.2 14.6 1.9 8.3 3.6 3.2 3 0 0 3 3 3 0 zinc-ribbon domain zf-C3HC4_3 PF13920.6 EAQ90998.1 - 3.3 7.6 12.7 10 6.1 9.0 2.8 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) PhoLip_ATPase_C PF16212.5 EAQ90999.1 - 6.5e-78 261.9 17.5 1.2e-77 261.0 17.5 1.5 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EAQ90999.1 - 2e-24 85.1 4.6 4.9e-24 83.8 4.6 1.7 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 EAQ90999.1 - 2.4e-12 47.6 2.5 8.2e-08 32.8 0.5 2.8 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EAQ90999.1 - 7e-12 45.3 0.0 3.7e-11 43.0 0.0 2.1 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 EAQ90999.1 - 2.3e-08 33.8 0.0 5.9e-08 32.4 0.0 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 EAQ90999.1 - 0.00075 19.3 0.4 0.0052 16.6 0.4 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Imm49 PF15575.6 EAQ90999.1 - 0.28 10.9 1.3 0.44 10.3 0.1 1.9 2 0 0 2 2 2 0 Immunity protein 49 Ecl1 PF12855.7 EAQ91000.1 - 2.5e-26 93.9 11.9 2.5e-26 93.9 11.9 2.0 2 0 0 2 2 2 1 ECL1/2/3 zinc binding proteins Kelch_5 PF13854.6 EAQ91001.1 - 8.4e-13 48.0 15.2 9.1e-12 44.7 0.4 5.3 5 0 0 5 5 5 2 Kelch motif Kelch_6 PF13964.6 EAQ91001.1 - 0.00095 19.4 20.1 1.1 9.7 0.5 5.9 5 1 1 6 6 6 4 Kelch motif Kelch_1 PF01344.25 EAQ91001.1 - 0.014 14.9 14.4 0.66 9.6 0.0 5.7 6 0 0 6 6 6 0 Kelch motif Podoplanin PF05808.11 EAQ91001.1 - 0.034 14.2 0.0 0.062 13.4 0.0 1.3 1 0 0 1 1 1 0 Podoplanin PGF-CTERM PF18204.1 EAQ91001.1 - 0.041 13.9 8.4 0.083 12.9 8.4 1.6 1 0 0 1 1 1 0 PGF-CTERM motif EphA2_TM PF14575.6 EAQ91001.1 - 0.1 13.5 0.0 0.25 12.2 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF347 PF03988.12 EAQ91001.1 - 0.16 12.1 1.8 0.34 11.1 1.8 1.5 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) Kelch_2 PF07646.15 EAQ91001.1 - 0.26 11.3 16.3 1.1 9.4 0.0 5.1 6 0 0 6 6 6 0 Kelch motif DUF4690 PF15756.5 EAQ91001.1 - 1.4 9.6 4.9 0.22 12.2 0.6 1.9 2 0 0 2 2 2 0 Small Novel Rich in Cartilage MFS_1 PF07690.16 EAQ91002.1 - 2.6e-17 62.8 51.0 1.9e-10 40.2 16.2 3.0 1 1 1 3 3 3 3 Major Facilitator Superfamily SNN_linker PF09050.10 EAQ91002.1 - 2.9 7.7 4.5 3.3 7.6 3.4 1.6 2 0 0 2 2 2 0 Stannin unstructured linker Zn_clus PF00172.18 EAQ91003.1 - 0.014 15.5 6.3 0.028 14.5 6.3 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain WAC_Acf1_DNA_bd PF10537.9 EAQ91004.1 - 1.7e-37 127.9 0.0 1.7e-37 127.9 0.0 2.3 3 0 0 3 3 3 1 ATP-utilising chromatin assembly and remodelling N-terminal WSD PF15613.6 EAQ91004.1 - 2.4e-17 63.2 0.0 2.4e-17 63.2 0.0 3.3 4 0 0 4 4 4 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DDT PF02791.17 EAQ91004.1 - 1.8e-15 56.9 0.4 3.4e-15 56.1 0.4 1.5 1 0 0 1 1 1 1 DDT domain WHIM1 PF15612.6 EAQ91004.1 - 1.2e-08 34.3 0.1 5.9e-08 32.1 0.0 2.2 2 0 0 2 2 2 1 WSTF, HB1, Itc1p, MBD9 motif 1 CCDC-167 PF15188.6 EAQ91004.1 - 0.29 11.5 0.0 0.29 11.5 0.0 3.6 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 CENP-B_dimeris PF09026.10 EAQ91004.1 - 3.3 8.1 9.6 9.2 6.7 1.1 3.0 2 0 0 2 2 2 0 Centromere protein B dimerisation domain CFIA_Pcf11 PF11526.8 EAQ91004.1 - 6.7 7.3 7.4 1.1 9.8 0.3 2.9 2 0 0 2 2 2 0 Subunit of cleavage factor IA Pcf11 Alg6_Alg8 PF03155.15 EAQ91005.1 - 7.1e-157 523.2 30.5 2.9e-123 412.4 17.3 2.0 1 1 1 2 2 2 2 ALG6, ALG8 glycosyltransferase family Lectin_leg-like PF03388.13 EAQ91006.1 - 6.9e-29 100.8 0.0 1.4e-28 99.8 0.0 1.5 1 0 0 1 1 1 1 Legume-like lectin family Baculo_PEP_C PF04513.12 EAQ91006.1 - 0.0025 17.9 0.0 0.12 12.4 0.0 2.3 1 1 1 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus TMF_TATA_bd PF12325.8 EAQ91006.1 - 0.056 13.7 0.5 7.2 6.9 0.0 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Peptidase_M24 PF00557.24 EAQ91007.1 - 1.6e-72 243.6 0.0 3.5e-72 242.5 0.0 1.6 1 1 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 EAQ91007.1 - 4.1e-21 75.0 0.1 9.8e-20 70.5 0.0 2.6 2 0 0 2 2 2 1 Aminopeptidase P, N-terminal domain Fungal_trans PF04082.18 EAQ91008.1 - 1.6e-32 112.6 0.2 3.1e-32 111.7 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF4699 PF15770.5 EAQ91008.1 - 2.1 8.1 10.4 4 7.1 10.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4699) Suf PF05843.14 EAQ91008.1 - 8.7 6.2 15.4 0.66 9.9 9.8 2.0 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) RPN7 PF10602.9 EAQ91011.1 - 8.4e-47 159.1 0.1 1.7e-46 158.1 0.1 1.6 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 EAQ91011.1 - 1e-15 58.1 0.1 7.4e-15 55.4 0.0 2.2 2 0 0 2 2 2 1 PCI domain COG2 PF06148.11 EAQ91011.1 - 0.027 14.6 0.3 0.15 12.2 0.0 2.2 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF2200 PF09966.9 EAQ91011.1 - 0.028 14.6 0.0 0.95 9.6 0.0 2.7 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2200) Prp18 PF02840.15 EAQ91012.1 - 3.3e-52 176.3 0.0 6.9e-52 175.3 0.0 1.5 1 0 0 1 1 1 1 Prp18 domain PRP4 PF08799.11 EAQ91012.1 - 1.2e-11 43.9 1.2 1.2e-11 43.9 1.2 2.9 2 0 0 2 2 2 1 pre-mRNA processing factor 4 (PRP4) like Mucin PF01456.17 EAQ91012.1 - 0.29 11.1 8.1 0.52 10.3 8.1 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF966 PF06136.13 EAQ91012.1 - 0.53 9.9 13.9 0.77 9.4 13.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) TT_ORF1 PF02956.14 EAQ91012.1 - 4.9 5.7 7.7 7 5.2 7.7 1.3 1 0 0 1 1 1 0 TT viral orf 1 Dicty_REP PF05086.12 EAQ91012.1 - 6.8 4.5 8.8 8.8 4.2 8.8 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SAP18 PF06487.12 EAQ91013.1 - 1.1e-15 58.0 0.0 1.4e-15 57.7 0.0 1.1 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) NDUF_B4 PF07225.12 EAQ91014.1 - 0.0042 17.0 0.1 0.0045 16.9 0.1 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) GST_N PF02798.20 EAQ91015.1 - 7.9e-08 32.5 0.0 1.7e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EAQ91015.1 - 7e-07 29.5 0.0 2.7e-06 27.6 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EAQ91015.1 - 5.6e-06 26.5 0.0 1e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EAQ91015.1 - 5.9e-06 26.6 0.0 1.1e-05 25.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EAQ91015.1 - 0.009 16.2 0.0 0.037 14.3 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EAQ91015.1 - 0.036 14.1 0.0 0.079 13.0 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Chordopox_L2 PF05803.12 EAQ91015.1 - 0.21 11.4 0.1 0.36 10.7 0.1 1.3 1 0 0 1 1 1 0 Chordopoxvirus L2 protein LCAT PF02450.15 EAQ91016.1 - 0.041 13.1 0.0 0.071 12.3 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Hydrolase_4 PF12146.8 EAQ91016.1 - 0.062 12.5 0.1 0.18 11.0 0.0 1.7 2 0 0 2 2 2 0 Serine aminopeptidase, S33 DUF676 PF05057.14 EAQ91016.1 - 0.068 12.7 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Synaptobrevin PF00957.21 EAQ91017.1 - 0.16 11.8 0.0 0.16 11.8 0.0 2.5 3 0 0 3 3 3 0 Synaptobrevin DUF5368 PF17336.2 EAQ91017.1 - 0.56 10.4 9.8 0.071 13.3 2.5 2.3 3 0 0 3 3 3 0 Family of unknown function (DUF5368) MIF PF01187.18 EAQ91018.1 - 3.5e-07 30.5 0.0 5.4e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Gtr1_RagA PF04670.12 EAQ91019.1 - 5.4e-71 238.6 0.1 6.4e-71 238.4 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 EAQ91019.1 - 0.011 15.2 0.0 0.018 14.5 0.0 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA_16 PF13191.6 EAQ91019.1 - 0.018 15.5 0.0 0.051 14.0 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain Roc PF08477.13 EAQ91019.1 - 0.033 14.4 0.0 0.064 13.5 0.0 1.6 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 EAQ91019.1 - 0.063 13.4 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase GGACT PF06094.12 EAQ91020.1 - 2.1e-07 31.5 0.0 4e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like AIG2_2 PF13772.6 EAQ91020.1 - 0.001 19.4 0.0 0.0045 17.3 0.0 1.9 2 0 0 2 2 2 1 AIG2-like family GGACT PF06094.12 EAQ91022.1 - 3.7e-10 40.5 0.1 8.5e-10 39.3 0.1 1.6 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like AIG2_2 PF13772.6 EAQ91022.1 - 0.00017 21.9 0.1 0.0016 18.8 0.0 2.5 3 0 0 3 3 3 1 AIG2-like family Caprin-1_dimer PF18293.1 EAQ91023.1 - 0.18 12.3 0.1 0.3 11.6 0.1 1.2 1 0 0 1 1 1 0 Caprin-1 dimerization domain DUF2428 PF10350.9 EAQ91025.1 - 4.5e-56 190.1 0.0 1e-55 189.0 0.0 1.7 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.22 EAQ91025.1 - 2.8e-06 27.1 14.7 7.9 7.0 0.1 7.9 8 0 0 8 8 8 3 HEAT repeat HEAT_2 PF13646.6 EAQ91025.1 - 0.0007 19.9 4.2 0.044 14.2 0.1 4.7 4 1 1 5 5 5 1 HEAT repeats EELM2 PF15863.5 EAQ91025.1 - 0.014 15.5 0.1 0.028 14.5 0.1 1.4 1 0 0 1 1 1 0 Extended EGL-27 and MTA1 homology domain HEAT_EZ PF13513.6 EAQ91025.1 - 2 9.0 6.2 94 3.7 0.6 4.9 4 1 0 4 4 4 0 HEAT-like repeat Tim17 PF02466.19 EAQ91026.1 - 1.7e-25 89.6 4.0 2.4e-25 89.0 4.0 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family CoaE PF01121.20 EAQ91029.1 - 9.6e-42 142.7 0.0 1e-40 139.3 0.0 2.0 1 1 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.6 EAQ91029.1 - 0.0029 18.2 0.5 0.29 11.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain p450 PF00067.22 EAQ91031.1 - 1.2e-41 143.0 0.0 4.2e-38 131.3 0.0 2.1 1 1 1 2 2 2 2 Cytochrome P450 DUF1749 PF08538.10 EAQ91032.1 - 5.6e-84 281.8 0.0 6.9e-84 281.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.7 EAQ91032.1 - 4.7e-06 27.4 3.8 6.3e-06 26.9 3.8 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Pkinase PF00069.25 EAQ91033.1 - 1.8e-38 132.4 0.0 2.7e-38 131.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ91033.1 - 2.8e-25 89.1 0.0 4e-25 88.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EAQ91033.1 - 0.0077 16.2 0.6 3.2 7.6 0.0 3.2 2 1 1 3 3 3 2 Phosphotransferase enzyme family HEAT_2 PF13646.6 EAQ91034.1 - 0.22 11.9 1.1 15 6.1 0.0 3.3 2 0 0 2 2 2 0 HEAT repeats SYF2 PF08231.12 EAQ91035.1 - 8.4e-06 26.3 0.7 8.4e-06 26.3 0.7 1.9 2 0 0 2 2 2 1 SYF2 splicing factor TMP_2 PF06791.13 EAQ91035.1 - 0.036 13.7 2.1 0.041 13.5 2.1 1.1 1 0 0 1 1 1 0 Prophage tail length tape measure protein NAD_binding_10 PF13460.6 EAQ91036.1 - 1.4e-09 38.2 0.0 0.0016 18.3 0.0 2.2 2 0 0 2 2 2 2 NAD(P)H-binding Epimerase PF01370.21 EAQ91036.1 - 3.1e-06 26.8 0.0 7e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EAQ91036.1 - 0.00015 20.9 0.0 0.0003 19.9 0.0 1.5 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EAQ91036.1 - 0.0068 15.6 0.0 0.06 12.5 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein RmlD_sub_bind PF04321.17 EAQ91036.1 - 0.015 14.4 0.0 0.069 12.2 0.0 2.0 2 1 1 3 3 3 0 RmlD substrate binding domain DUF3168 PF11367.8 EAQ91036.1 - 0.087 13.0 0.5 0.22 11.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3168) NmrA PF05368.13 EAQ91036.1 - 0.13 11.7 0.0 0.46 10.0 0.0 1.8 2 0 0 2 2 2 0 NmrA-like family YEATS PF03366.16 EAQ91037.1 - 7e-30 102.8 0.3 1.1e-29 102.3 0.3 1.3 1 0 0 1 1 1 1 YEATS family DUF4191 PF13829.6 EAQ91037.1 - 0.2 11.0 1.3 0.28 10.5 1.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) Ins_P5_2-kin PF06090.12 EAQ91039.1 - 2.9e-25 89.4 0.0 3.8e-15 56.2 0.0 2.0 1 1 1 2 2 2 2 Inositol-pentakisphosphate 2-kinase Nucleoside_tran PF01733.18 EAQ91040.1 - 5.8e-39 134.3 7.0 1.3e-29 103.6 0.0 2.7 3 0 0 3 3 3 2 Nucleoside transporter MFS_1 PF07690.16 EAQ91040.1 - 2.2e-06 26.9 44.8 0.0004 19.4 8.1 3.0 1 1 2 3 3 3 3 Major Facilitator Superfamily Metal_hydrol PF10118.9 EAQ91040.1 - 0.31 10.7 1.4 2.7 7.6 0.4 2.2 2 0 0 2 2 2 0 Predicted metal-dependent hydrolase DUF3927 PF13064.6 EAQ91040.1 - 0.46 10.5 3.3 1.4 9.0 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3927) DUF2975 PF11188.8 EAQ91040.1 - 2.1 8.3 16.5 0.066 13.1 0.8 3.8 3 1 1 4 4 4 0 Protein of unknown function (DUF2975) Catalase PF00199.19 EAQ91041.1 - 3.3e-149 497.2 0.1 8.3e-149 495.9 0.1 1.6 1 1 0 1 1 1 1 Catalase Catalase_C PF18011.1 EAQ91041.1 - 5.8e-50 168.9 0.3 1.1e-49 168.0 0.3 1.5 1 0 0 1 1 1 1 C-terminal domain found in long catalases Catalase-rel PF06628.12 EAQ91041.1 - 1.7e-20 73.0 0.0 3.1e-20 72.1 0.0 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive Haspin_kinase PF12330.8 EAQ91042.1 - 5e-11 42.2 0.0 3.9e-07 29.3 0.0 2.0 2 0 0 2 2 2 2 Haspin like kinase domain DUF1682 PF07946.14 EAQ91043.1 - 9.5e-100 333.9 3.6 1.2e-99 333.6 3.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) Big_3 PF07523.12 EAQ91043.1 - 0.095 13.0 0.2 1.1 9.6 0.0 2.3 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 3) Thiamine_BP PF01910.17 EAQ91044.1 - 1.6e-33 114.5 0.8 1.8e-33 114.3 0.8 1.0 1 0 0 1 1 1 1 Thiamine-binding protein Polysacc_deac_1 PF01522.21 EAQ91044.1 - 0.031 14.2 0.1 0.04 13.8 0.1 1.3 1 0 0 1 1 1 0 Polysaccharide deacetylase DUF1522 PF07482.11 EAQ91044.1 - 0.058 13.7 0.1 0.073 13.4 0.1 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1522) SR-25 PF10500.9 EAQ91045.1 - 0.014 15.1 0.1 0.024 14.3 0.1 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Trypan_PARP PF05887.11 EAQ91045.1 - 9.9 6.1 11.5 15 5.6 1.6 2.5 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Arf PF00025.21 EAQ91046.1 - 6.9e-21 74.5 0.1 4.9e-11 42.4 0.0 2.1 1 1 1 2 2 2 2 ADP-ribosylation factor family G-alpha PF00503.20 EAQ91046.1 - 7.3e-05 22.1 0.0 0.016 14.4 0.0 2.1 2 0 0 2 2 2 2 G-protein alpha subunit GTP_EFTU PF00009.27 EAQ91046.1 - 0.0043 16.6 0.0 0.014 15.0 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 EAQ91046.1 - 0.17 11.3 0.0 15 5.0 0.0 2.1 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 EAQ91046.1 - 0.25 10.7 0.0 0.31 10.4 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region RNase_PH PF01138.21 EAQ91047.1 - 8.2e-22 78.1 0.0 1.2e-21 77.6 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 EAQ91047.1 - 2.8e-06 27.3 0.0 6.4e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Cwf_Cwc_15 PF04889.12 EAQ91048.1 - 8e-89 297.6 16.4 1.2e-88 297.0 16.4 1.3 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 EAQ91048.1 - 0.099 11.9 16.0 0.16 11.3 16.0 1.3 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.12 EAQ91048.1 - 0.19 9.9 22.7 0.23 9.7 22.7 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 EAQ91048.1 - 0.34 10.3 20.8 0.44 9.9 20.8 1.2 1 0 0 1 1 1 0 SDA1 Casc1_N PF15927.5 EAQ91048.1 - 0.35 10.5 9.6 0.66 9.6 9.6 1.4 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus BUD22 PF09073.10 EAQ91048.1 - 1.2 8.4 21.5 1.5 8.1 21.5 1.2 1 0 0 1 1 1 0 BUD22 DNA_pol_phi PF04931.13 EAQ91048.1 - 4.7 5.2 24.1 6.2 4.8 24.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi EBP PF05241.12 EAQ91049.1 - 1.6e-55 187.4 7.7 1.8e-55 187.1 7.7 1.0 1 0 0 1 1 1 1 Emopamil binding protein Methyltr_RsmB-F PF01189.17 EAQ91050.1 - 2.6e-12 46.8 0.0 4.9e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F ProSAAS PF07259.12 EAQ91050.1 - 0.07 13.1 0.4 0.24 11.4 0.0 1.9 2 0 0 2 2 2 0 ProSAAS precursor DUF1996 PF09362.10 EAQ91051.1 - 1.1e-59 202.3 0.0 1.5e-59 201.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) WSC PF01822.19 EAQ91051.1 - 6.9e-19 67.8 8.8 6.9e-19 67.8 8.8 2.2 2 0 0 2 2 2 1 WSC domain TPR_11 PF13414.6 EAQ91053.1 - 2.9e-10 39.6 4.1 0.13 11.9 0.1 6.2 5 1 1 6 6 6 3 TPR repeat TPR_1 PF00515.28 EAQ91053.1 - 1.8e-09 37.0 14.8 0.087 12.7 0.0 7.8 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_2 PF07719.17 EAQ91053.1 - 1.8e-09 37.0 20.4 0.44 10.8 0.0 9.8 11 0 0 11 11 10 4 Tetratricopeptide repeat TPR_19 PF14559.6 EAQ91053.1 - 1.8e-08 34.7 9.2 0.23 12.0 0.2 6.1 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 EAQ91053.1 - 2.2e-08 34.6 22.3 0.17 12.6 0.0 8.3 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_14 PF13428.6 EAQ91053.1 - 1.2e-06 28.8 17.7 0.062 14.1 0.0 9.6 8 3 3 11 11 10 1 Tetratricopeptide repeat TPR_8 PF13181.6 EAQ91053.1 - 1.5e-06 28.0 15.3 0.55 10.6 0.3 8.1 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_7 PF13176.6 EAQ91053.1 - 4.1e-06 26.4 10.2 1.6 8.9 0.0 6.8 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_20 PF14561.6 EAQ91053.1 - 7.5e-06 26.2 1.5 0.039 14.3 0.0 4.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 EAQ91053.1 - 0.0021 18.3 0.2 2.1e+02 2.7 0.0 6.5 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_10 PF13374.6 EAQ91053.1 - 0.043 13.7 9.0 76 3.4 0.1 6.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_MalT PF17874.1 EAQ91053.1 - 0.05 13.0 1.6 0.86 8.9 0.1 3.1 3 0 0 3 3 3 0 MalT-like TPR region TPR_12 PF13424.6 EAQ91053.1 - 0.16 12.3 27.7 0.65 10.3 1.1 7.3 7 1 0 7 7 7 0 Tetratricopeptide repeat TPR_6 PF13174.6 EAQ91053.1 - 1.5 9.6 14.4 12 6.8 0.1 6.6 7 0 0 7 7 6 0 Tetratricopeptide repeat SAM_2 PF07647.17 EAQ91054.1 - 2.1e-09 37.3 0.2 3.8e-09 36.5 0.2 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 EAQ91054.1 - 8.4e-05 22.9 0.3 0.00016 22.0 0.3 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) IGR PF09597.10 EAQ91054.1 - 0.011 15.9 0.2 0.028 14.5 0.1 1.7 2 0 0 2 2 2 0 IGR protein motif DUF4508 PF14969.6 EAQ91054.1 - 0.12 12.7 0.1 0.29 11.4 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4508) Ribosomal_L29e PF01779.17 EAQ91055.1 - 3.2e-23 81.8 9.2 4.7e-23 81.2 9.2 1.3 1 0 0 1 1 1 1 Ribosomal L29e protein family Mito_carr PF00153.27 EAQ91056.1 - 1e-47 160.0 0.8 2.9e-16 59.1 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Peptidase_C2 PF00648.21 EAQ91057.1 - 3.7e-31 108.2 0.0 5.5e-31 107.7 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 EAQ91057.1 - 0.0061 16.8 0.1 0.022 15.0 0.0 1.9 2 0 0 2 2 2 1 Calpain large subunit, domain III ADH_N PF08240.12 EAQ91060.1 - 6.6e-31 106.4 2.2 8.8e-31 106.0 2.2 1.1 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_assoc PF13823.6 EAQ91060.1 - 3e-06 27.0 0.1 7.7e-06 25.7 0.1 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated Mcm10 PF09332.11 EAQ91060.1 - 1.9 7.8 3.3 2.8 7.3 3.3 1.2 1 0 0 1 1 1 0 Mcm10 replication factor Sen15 PF09631.10 EAQ91061.1 - 1.7e-22 79.6 0.0 2.8e-22 78.9 0.0 1.3 1 1 0 1 1 1 1 Sen15 protein Pkinase PF00069.25 EAQ91062.1 - 0.001 18.5 0.0 0.014 14.7 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain DIM1 PF02966.16 EAQ91063.1 - 5e-69 230.2 0.0 5.7e-69 230.0 0.0 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 DUF2985 PF11204.8 EAQ91064.1 - 6.8e-37 125.5 0.7 1.4e-36 124.5 0.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) Nuc_sug_transp PF04142.15 EAQ91065.1 - 8.5e-08 31.7 1.0 1.1e-07 31.3 0.2 1.6 2 0 0 2 2 2 1 Nucleotide-sugar transporter TPT PF03151.16 EAQ91065.1 - 0.00025 20.5 0.6 0.00025 20.5 0.6 1.9 2 0 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.20 EAQ91065.1 - 0.00026 21.2 31.0 0.0075 16.4 7.1 3.1 3 1 0 3 3 3 2 EamA-like transporter family OppC_N PF12911.7 EAQ91065.1 - 0.092 12.7 1.4 0.34 10.9 0.2 2.7 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C Yippee-Mis18 PF03226.14 EAQ91066.1 - 1.2e-16 60.8 0.1 1.6e-16 60.4 0.1 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.8 EAQ91066.1 - 0.13 12.5 0.3 0.2 11.9 0.3 1.2 1 0 0 1 1 1 0 C-terminal domain of RIG-I Ferric_reduct PF01794.19 EAQ91067.1 - 5e-24 84.8 11.0 4.1e-23 81.9 12.1 2.0 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 EAQ91067.1 - 1.2e-18 67.7 0.0 6.9e-16 58.8 0.0 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EAQ91067.1 - 3e-10 40.1 0.0 6.4e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain CLU PF13236.6 EAQ91070.1 - 2.9e-54 184.2 0.0 1.4e-34 119.9 0.0 2.5 1 1 1 2 2 2 2 Clustered mitochondria eIF3_p135 PF12807.7 EAQ91070.1 - 4.4e-53 179.9 1.2 1.1e-52 178.6 0.0 2.2 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.6 EAQ91070.1 - 1e-29 102.6 9.9 2.2e-13 50.3 0.0 4.3 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 EAQ91070.1 - 5.6e-24 83.3 5.8 1.3e-06 28.0 0.0 6.0 5 1 1 6 6 6 4 Tetratricopeptide repeat CLU_N PF15044.6 EAQ91070.1 - 8.6e-21 74.1 0.1 2.4e-20 72.7 0.1 1.8 1 0 0 1 1 1 1 Mitochondrial function, CLU-N-term DUF727 PF05303.12 EAQ91070.1 - 6.6e-05 22.9 0.0 0.00018 21.5 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF727) TPR_8 PF13181.6 EAQ91070.1 - 0.0015 18.6 7.8 0.019 15.1 0.5 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 EAQ91070.1 - 0.3 11.3 12.7 1.8 8.9 0.4 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.6 EAQ91070.1 - 0.32 11.5 1.3 35 5.1 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat CDC45 PF02724.14 EAQ91070.1 - 5.3 5.2 10.6 8.2 4.6 10.6 1.2 1 0 0 1 1 1 0 CDC45-like protein Forkhead PF00250.18 EAQ91071.1 - 4.6e-33 113.3 0.6 8.5e-33 112.5 0.6 1.4 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 EAQ91071.1 - 3.8e-05 23.9 0.0 8.3e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EAQ91071.1 - 0.013 15.8 0.0 0.024 14.9 0.0 1.3 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain Linker_histone PF00538.19 EAQ91071.1 - 0.13 12.7 0.1 0.24 11.8 0.1 1.4 1 0 0 1 1 1 0 linker histone H1 and H5 family DUF4632 PF15451.6 EAQ91071.1 - 9.2 6.4 7.6 12 6.1 1.4 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4632) Aminotran_3 PF00202.21 EAQ91072.1 - 2.9e-72 243.6 0.0 4.2e-72 243.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-III AhpC-TSA_2 PF13911.6 EAQ91073.1 - 2.4e-06 27.6 0.0 4.8e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme Fungal_trans_2 PF11951.8 EAQ91073.1 - 5.9e-06 25.3 0.3 9.8e-06 24.6 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain AAA PF00004.29 EAQ91075.1 - 2.8e-98 325.4 0.0 1.2e-47 161.6 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EAQ91075.1 - 3.9e-24 84.2 1.9 1e-12 47.7 0.4 2.8 2 0 0 2 2 2 2 AAA+ lid domain CDC48_N PF02359.18 EAQ91075.1 - 1.6e-18 66.6 0.5 6.2e-18 64.8 0.5 2.1 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 EAQ91075.1 - 2.1e-14 53.5 0.0 6.1e-06 26.1 0.0 3.4 4 1 0 4 4 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 EAQ91075.1 - 1.3e-13 51.4 0.0 3.1e-07 30.7 0.0 2.8 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 EAQ91075.1 - 2.1e-13 51.0 0.0 0.00017 22.0 0.0 4.2 2 2 1 3 3 3 2 AAA ATPase domain AAA_5 PF07728.14 EAQ91075.1 - 4.6e-12 46.1 0.3 3.5e-06 27.0 0.1 3.8 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 EAQ91075.1 - 7.2e-12 45.7 0.0 3.9e-05 23.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 EAQ91075.1 - 1.8e-09 38.0 0.4 0.029 14.7 0.0 4.0 2 2 1 3 3 3 2 AAA domain TIP49 PF06068.13 EAQ91075.1 - 2.9e-09 36.6 0.0 0.0013 18.0 0.0 2.8 2 0 0 2 2 2 2 TIP49 P-loop domain CDC48_2 PF02933.17 EAQ91075.1 - 8.2e-08 31.9 0.0 1.8e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_18 PF13238.6 EAQ91075.1 - 1.8e-07 31.8 0.0 0.029 14.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 EAQ91075.1 - 2e-07 30.6 0.2 0.0069 15.8 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 EAQ91075.1 - 3.4e-07 30.2 0.0 0.019 14.7 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_14 PF13173.6 EAQ91075.1 - 3.4e-07 30.4 0.0 0.0076 16.3 0.0 3.0 3 0 0 3 3 3 2 AAA domain RNA_helicase PF00910.22 EAQ91075.1 - 5.7e-07 29.9 0.0 0.031 14.6 0.0 2.9 3 0 0 3 3 2 2 RNA helicase ATPase PF06745.13 EAQ91075.1 - 1.1e-06 28.1 0.3 0.26 10.6 0.0 3.5 3 0 0 3 3 3 2 KaiC AAA_25 PF13481.6 EAQ91075.1 - 1.5e-06 27.9 4.1 0.24 10.9 0.1 4.7 3 2 2 5 5 5 2 AAA domain AAA_7 PF12775.7 EAQ91075.1 - 2.1e-06 27.4 0.0 0.037 13.5 0.0 2.9 2 1 0 2 2 2 2 P-loop containing dynein motor region Vps4_C PF09336.10 EAQ91075.1 - 2.6e-06 27.3 0.4 2.4e-05 24.2 0.1 2.5 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain DUF815 PF05673.13 EAQ91075.1 - 3e-06 26.6 0.0 0.0075 15.5 0.0 2.8 3 0 0 3 3 3 2 Protein of unknown function (DUF815) AAA_24 PF13479.6 EAQ91075.1 - 4.5e-06 26.5 0.0 0.082 12.6 0.0 2.8 3 0 0 3 3 2 2 AAA domain Parvo_NS1 PF01057.17 EAQ91075.1 - 9.4e-06 24.9 0.1 0.052 12.6 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_28 PF13521.6 EAQ91075.1 - 1.9e-05 25.0 0.0 0.18 12.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.26 EAQ91075.1 - 2.5e-05 24.1 0.0 0.25 11.0 0.0 3.2 2 2 0 2 2 2 2 Sigma-54 interaction domain ABC_tran PF00005.27 EAQ91075.1 - 2.8e-05 24.7 0.0 0.28 11.7 0.0 3.5 2 1 0 2 2 2 2 ABC transporter Bac_DnaA PF00308.18 EAQ91075.1 - 4.2e-05 23.5 0.0 0.22 11.3 0.0 3.0 3 0 0 3 3 3 2 Bacterial dnaA protein TsaE PF02367.17 EAQ91075.1 - 6.9e-05 22.8 0.0 0.41 10.6 0.0 2.6 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE ResIII PF04851.15 EAQ91075.1 - 0.00012 22.1 0.0 0.045 13.8 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit NACHT PF05729.12 EAQ91075.1 - 0.00013 21.9 0.1 0.18 11.7 0.0 2.9 3 0 0 3 3 3 1 NACHT domain AAA_17 PF13207.6 EAQ91075.1 - 0.00023 21.6 0.0 0.59 10.6 0.0 2.9 2 0 0 2 2 2 1 AAA domain PhoH PF02562.16 EAQ91075.1 - 0.00024 20.6 0.3 0.68 9.3 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein AAA_3 PF07726.11 EAQ91075.1 - 0.00024 21.0 0.0 0.7 9.7 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 EAQ91075.1 - 0.00037 20.4 0.2 1 9.1 0.0 2.6 3 0 0 3 3 2 2 AAA domain AAA_30 PF13604.6 EAQ91075.1 - 0.00046 19.9 0.3 1.1 8.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain ATPase_2 PF01637.18 EAQ91075.1 - 0.00066 19.7 0.0 2.1 8.2 0.0 3.5 3 1 0 3 3 3 1 ATPase domain predominantly from Archaea AAA_19 PF13245.6 EAQ91075.1 - 0.0015 18.9 0.8 5.9 7.2 0.0 3.6 3 1 1 4 4 3 0 AAA domain DUF2075 PF09848.9 EAQ91075.1 - 0.0021 17.4 0.0 1.7 7.8 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) Sigma54_activ_2 PF14532.6 EAQ91075.1 - 0.004 17.3 0.0 0.55 10.3 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain NB-ARC PF00931.22 EAQ91075.1 - 0.0044 16.2 0.0 1.4 8.0 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain Viral_helicase1 PF01443.18 EAQ91075.1 - 0.0087 15.8 0.0 0.34 10.6 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.15 EAQ91075.1 - 0.0092 15.9 1.3 2.5 8.0 0.0 4.0 5 0 0 5 5 3 1 NTPase IPT PF01745.16 EAQ91075.1 - 0.013 14.9 0.0 1.8 7.9 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase KAP_NTPase PF07693.14 EAQ91075.1 - 0.014 14.7 0.5 1.1 8.4 0.0 3.2 2 2 1 4 4 4 0 KAP family P-loop domain Zeta_toxin PF06414.12 EAQ91075.1 - 0.022 14.0 0.5 7.9 5.7 0.0 2.9 3 0 0 3 3 3 0 Zeta toxin AAA_6 PF12774.7 EAQ91075.1 - 0.05 12.6 0.1 7.6 5.4 0.0 2.4 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region Cytidylate_kin PF02224.18 EAQ91075.1 - 0.058 13.1 0.0 10 5.8 0.0 2.7 2 0 0 2 2 2 0 Cytidylate kinase Zot PF05707.12 EAQ91075.1 - 0.062 12.9 0.1 3 7.5 0.0 3.1 2 2 1 3 3 3 0 Zonular occludens toxin (Zot) Cytidylate_kin2 PF13189.6 EAQ91075.1 - 0.067 13.3 0.0 3.3 7.8 0.0 2.4 2 0 0 2 2 2 0 Cytidylate kinase-like family AFG1_ATPase PF03969.16 EAQ91075.1 - 0.092 11.6 0.0 11 4.8 0.0 2.2 2 0 0 2 2 2 0 AFG1-like ATPase UFD1 PF03152.14 EAQ91075.1 - 0.096 12.2 0.0 0.42 10.1 0.0 1.9 1 1 1 2 2 2 0 Ubiquitin fusion degradation protein UFD1 EnY2 PF10163.9 EAQ91076.1 - 0.0013 19.0 0.0 0.0025 18.1 0.0 1.4 1 0 0 1 1 1 1 Transcription factor e(y)2 DUF2742 PF10888.8 EAQ91079.1 - 0.0076 16.5 0.3 0.012 15.9 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2742) ABC_membrane PF00664.23 EAQ91080.1 - 2.2e-34 119.4 2.9 5e-34 118.2 2.9 1.6 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EAQ91080.1 - 1.5e-30 106.5 0.0 3.1e-30 105.5 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EAQ91080.1 - 6.9e-05 22.4 0.0 0.00041 19.9 0.0 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EAQ91080.1 - 0.011 15.7 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase SbcCD_C PF13558.6 EAQ91080.1 - 0.042 14.1 0.5 1.4 9.2 0.1 3.4 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 EAQ91080.1 - 0.095 12.5 0.1 0.24 11.2 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_10 PF12846.7 EAQ91080.1 - 0.13 11.2 0.0 0.23 10.4 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain TRAM_LAG1_CLN8 PF03798.16 EAQ91081.1 - 2.8e-35 121.9 20.5 2.8e-35 121.9 20.5 1.8 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 EAQ91081.1 - 1.6e-25 88.5 0.1 1.6e-25 88.5 0.1 2.7 3 0 0 3 3 3 1 TRAM1-like protein TrkH PF02386.16 EAQ91082.1 - 9.8e-104 347.6 11.4 4.3e-97 325.6 6.7 3.1 2 1 1 3 3 3 3 Cation transport protein Na_H_Exchanger PF00999.21 EAQ91083.1 - 1.2e-19 70.4 11.3 4.2e-10 39.0 1.5 3.0 2 1 0 2 2 2 2 Sodium/hydrogen exchanger family YrhC PF14143.6 EAQ91083.1 - 6.7e-05 22.9 0.1 6.7e-05 22.9 0.1 2.9 4 0 0 4 4 4 1 YrhC-like protein zf-CCCH_8 PF18633.1 EAQ91083.1 - 0.092 12.9 0.5 0.17 12.0 0.5 1.4 1 0 0 1 1 1 0 Zinc-finger antiviral protein (ZAP) zinc finger domain 3 APH PF01636.23 EAQ91085.1 - 2e-11 44.3 0.3 3.4e-10 40.3 0.0 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family PalH PF08733.10 EAQ91086.1 - 1.6e-113 379.1 0.0 1.9e-113 378.8 0.0 1.1 1 0 0 1 1 1 1 PalH/RIM21 NnrU PF07298.11 EAQ91086.1 - 0.047 13.2 3.7 2.1 7.8 2.3 2.5 2 0 0 2 2 2 0 NnrU protein SH3_1 PF00018.28 EAQ91087.1 - 0.013 15.1 0.0 0.028 14.0 0.0 1.6 1 0 0 1 1 1 0 SH3 domain GH131_N PF18271.1 EAQ91088.1 - 3.5e-49 167.8 0.8 4.9e-49 167.3 0.8 1.1 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain MFS_1 PF07690.16 EAQ91088.1 - 3.3e-05 23.0 6.9 0.0061 15.5 0.1 3.2 3 1 0 3 3 3 2 Major Facilitator Superfamily DUF4173 PF13777.6 EAQ91088.1 - 0.079 12.4 2.3 7.8 5.9 2.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4173) Polysacc_lyase PF14099.6 EAQ91088.1 - 0.095 12.5 2.1 0.18 11.6 2.1 1.4 1 0 0 1 1 1 0 Polysaccharide lyase Na_H_Exchanger PF00999.21 EAQ91089.1 - 7.7e-72 242.2 39.0 9.2e-72 241.9 39.0 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family PepSY_TM PF03929.16 EAQ91089.1 - 0.025 14.3 0.2 0.052 13.2 0.2 1.6 1 0 0 1 1 1 0 PepSY-associated TM region Misat_Tub_SegII PF10644.9 EAQ91091.1 - 2.1e-17 63.5 0.1 6.1e-17 62.0 0.0 1.8 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 EAQ91091.1 - 0.00031 20.5 0.0 0.00052 19.7 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Pyr_redox_2 PF07992.14 EAQ91092.1 - 1.5e-52 178.7 0.0 1.9e-52 178.4 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EAQ91092.1 - 3.7e-12 46.6 0.0 6.3e-11 42.7 0.1 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EAQ91092.1 - 0.00015 21.1 0.0 0.088 12.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase EcoR124_C PF12008.8 EAQ91092.1 - 0.05 13.3 0.0 0.08 12.6 0.0 1.2 1 0 0 1 1 1 0 Type I restriction and modification enzyme - subunit R C terminal Glyco_hydro_18 PF00704.28 EAQ91094.1 - 6.8e-38 131.1 0.0 8.9e-38 130.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.20 EAQ91094.1 - 2.2e-12 46.8 0.0 3e-05 24.0 0.0 3.0 3 0 0 3 3 3 2 LysM domain Chitin_bind_1 PF00187.19 EAQ91094.1 - 5.5e-06 26.7 6.1 5.5e-06 26.7 6.1 3.6 4 0 0 4 4 4 1 Chitin recognition protein SUB1_ProdP9 PF18213.1 EAQ91094.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 SUB1 protease Prodomain ProdP9 Peptidase_S8 PF00082.22 EAQ91095.1 - 0.00081 18.7 0.1 0.015 14.6 0.1 2.1 1 1 0 1 1 1 1 Subtilase family PfkB PF00294.24 EAQ91096.1 - 1.6e-29 103.1 1.2 1.3e-16 60.8 0.2 2.7 1 1 0 2 2 2 2 pfkB family carbohydrate kinase MFS_1 PF07690.16 EAQ91097.1 - 9.8e-13 47.7 7.9 9.8e-13 47.7 7.9 2.1 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EAQ91097.1 - 1.1e-05 24.5 1.8 0.00017 20.6 0.6 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter NACHT_N PF17100.5 EAQ91099.1 - 5.3e-77 258.6 0.1 8.3e-77 258.0 0.1 1.3 1 0 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase WD40 PF00400.32 EAQ91099.1 - 3.6e-51 170.0 16.7 2.5e-09 37.6 0.2 7.1 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAQ91099.1 - 4.9e-21 74.8 0.3 0.0034 17.6 0.0 6.2 2 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 EAQ91099.1 - 2.3e-14 53.7 0.3 4.6e-14 52.7 0.3 1.5 1 0 0 1 1 1 1 NACHT domain Ge1_WD40 PF16529.5 EAQ91099.1 - 2.9e-12 46.2 1.3 0.14 11.1 0.0 5.6 1 1 4 5 5 5 4 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EAQ91099.1 - 1.9e-09 36.7 7.2 0.081 11.6 0.0 5.1 2 1 3 5 5 5 4 Nucleoporin Nup120/160 PD40 PF07676.12 EAQ91099.1 - 2.8e-05 23.9 9.1 3.7 7.6 0.0 6.4 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat AAA_16 PF13191.6 EAQ91099.1 - 0.0096 16.3 0.0 0.032 14.6 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain VID27 PF08553.10 EAQ91099.1 - 0.011 14.8 0.4 15 4.5 0.0 3.1 1 1 2 3 3 3 0 VID27 C-terminal WD40-like domain HARP PF07443.13 EAQ91099.1 - 0.012 15.2 0.0 12 5.6 0.0 4.2 4 0 0 4 4 4 0 HepA-related protein (HARP) Ret2_MD PF18528.1 EAQ91099.1 - 0.03 14.7 0.0 39 4.7 0.0 4.5 2 2 3 5 5 5 0 RNA editing 3' terminal uridylyl transferase 2 middle domain ResIII PF04851.15 EAQ91099.1 - 0.069 13.2 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DUF2075 PF09848.9 EAQ91099.1 - 0.13 11.5 0.0 0.26 10.5 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.22 EAQ91099.1 - 0.14 12.6 0.0 0.92 9.9 0.0 2.3 2 0 0 2 2 2 0 RNA helicase DUF4596 PF15363.6 EAQ91099.1 - 0.92 9.8 3.2 7.4 6.9 0.2 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4596) Pkinase_Tyr PF07714.17 EAQ91100.1 - 5e-18 65.3 0.0 5.1e-17 62.0 0.0 2.3 1 1 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 EAQ91100.1 - 9.4e-17 61.2 0.0 2e-16 60.1 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 EAQ91100.1 - 2.7e-05 23.6 0.0 6e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EAQ91100.1 - 0.0039 16.8 0.0 0.0099 15.5 0.0 1.6 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 EAQ91100.1 - 0.02 14.8 0.2 0.089 12.7 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family UvrD_C_2 PF13538.6 EAQ91100.1 - 0.022 14.6 0.0 0.077 12.8 0.0 2.0 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain Kinase-like PF14531.6 EAQ91100.1 - 0.025 13.9 0.0 0.085 12.2 0.0 1.8 1 1 0 1 1 1 0 Kinase-like PAP_central PF04928.17 EAQ91101.1 - 1.7e-78 263.0 0.0 2.5e-78 262.5 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 EAQ91101.1 - 5e-26 91.3 0.2 5e-26 91.3 0.2 1.7 2 0 0 2 2 2 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 EAQ91101.1 - 1.5e-08 34.9 0.0 4.6e-08 33.3 0.0 1.8 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 EAQ91101.1 - 0.017 15.2 0.0 0.042 13.9 0.0 1.6 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase Abhydrolase_6 PF12697.7 EAQ91102.1 - 5.3e-06 27.2 0.9 3.8e-05 24.4 0.9 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 EAQ91102.1 - 3.3e-05 23.7 0.1 5.4e-05 23.0 0.1 1.3 1 0 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.8 EAQ91102.1 - 0.015 14.6 0.0 0.029 13.6 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Lipase_3 PF01764.25 EAQ91102.1 - 0.019 14.8 0.0 0.036 13.9 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Thioesterase PF00975.20 EAQ91102.1 - 0.02 15.0 0.0 0.049 13.7 0.0 1.6 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_3 PF07859.13 EAQ91102.1 - 0.027 14.3 0.1 0.11 12.3 0.0 2.0 2 1 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 EAQ91102.1 - 0.074 12.8 0.0 0.2 11.4 0.0 1.6 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase DUF676 PF05057.14 EAQ91102.1 - 0.14 11.7 0.0 0.58 9.6 0.0 1.9 1 1 0 1 1 1 0 Putative serine esterase (DUF676) PTPLA PF04387.14 EAQ91103.1 - 4.4e-32 111.1 12.3 6.2e-31 107.3 11.1 2.3 1 1 1 2 2 2 2 Protein tyrosine phosphatase-like protein, PTPLA tRNA-synt_2d PF01409.20 EAQ91105.1 - 8.4e-68 228.5 0.4 8.3e-67 225.2 0.1 2.4 2 1 0 2 2 2 1 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 EAQ91105.1 - 5.6e-18 65.0 0.6 1.2e-17 63.9 0.6 1.6 1 0 0 1 1 1 1 PheRS DNA binding domain 3 tRNA_synthFbeta PF17759.1 EAQ91105.1 - 4.1e-07 29.7 0.0 0.13 11.7 0.0 3.2 3 0 0 3 3 3 2 Phenylalanyl tRNA synthetase beta chain CLM domain PheRS_DBD2 PF18554.1 EAQ91105.1 - 1.8e-05 24.6 4.9 1.8e-05 24.6 4.9 2.0 2 0 0 2 2 2 1 PheRS DNA binding domain 2 tRNA-synt_2 PF00152.20 EAQ91105.1 - 0.75 8.8 3.2 26 3.7 0.0 3.4 4 0 0 4 4 4 0 tRNA synthetases class II (D, K and N) Arf PF00025.21 EAQ91106.1 - 1.7e-72 242.5 0.1 2e-72 242.3 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EAQ91106.1 - 2e-14 53.8 0.0 2.7e-14 53.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 EAQ91106.1 - 4.4e-12 45.8 0.0 5.5e-12 45.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 EAQ91106.1 - 1.1e-11 44.5 0.2 1.1e-07 31.3 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 EAQ91106.1 - 7.7e-10 38.6 0.0 9.3e-10 38.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 EAQ91106.1 - 3.5e-08 33.1 0.0 4.5e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EAQ91106.1 - 2.1e-06 27.8 0.0 3.3e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase MeaB PF03308.16 EAQ91106.1 - 0.00048 19.2 0.4 0.0012 17.9 0.1 1.7 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB GTP_EFTU PF00009.27 EAQ91106.1 - 0.0045 16.5 0.1 0.36 10.3 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 EAQ91106.1 - 0.026 14.0 0.6 0.11 12.1 0.6 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B VWA_3 PF13768.6 EAQ91106.1 - 0.088 12.7 0.0 0.76 9.7 0.1 2.0 2 0 0 2 2 2 0 von Willebrand factor type A domain VWA_CoxE PF05762.14 EAQ91106.1 - 0.14 11.5 0.0 0.19 11.1 0.0 1.1 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein Ribosomal_L39 PF00832.20 EAQ91107.1 - 4.5e-22 77.4 9.1 5.1e-22 77.2 9.1 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein Skp1 PF01466.19 EAQ91108.1 - 6e-29 99.9 0.7 1e-28 99.1 0.7 1.4 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 EAQ91108.1 - 5.3e-20 71.4 0.1 1.4e-19 70.0 0.0 1.8 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain Trnau1ap PF17654.1 EAQ91108.1 - 0.03 15.2 0.2 0.041 14.7 0.2 1.4 1 0 0 1 1 1 0 Selenocysteine tRNA 1 associated proteins Pet100 PF09803.9 EAQ91110.1 - 8.2e-21 74.3 0.1 1e-20 74.0 0.1 1.1 1 0 0 1 1 1 1 Pet100 DUF4140 PF13600.6 EAQ91110.1 - 0.11 13.0 0.2 0.13 12.7 0.2 1.1 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Transcrip_reg PF01709.20 EAQ91111.1 - 1e-75 254.2 0.8 1.2e-75 254.1 0.8 1.0 1 0 0 1 1 1 1 Transcriptional regulator VAPB_antitox PF02697.14 EAQ91111.1 - 0.056 14.2 0.6 0.13 13.1 0.6 1.6 1 0 0 1 1 1 0 Putative antitoxin HEAT_2 PF13646.6 EAQ91112.1 - 1.1e-09 38.5 10.3 0.083 13.3 0.0 8.1 7 1 1 8 8 8 3 HEAT repeats HEAT PF02985.22 EAQ91112.1 - 1.5e-08 34.2 19.9 0.032 14.5 0.1 10.3 11 0 0 11 11 11 2 HEAT repeat Cnd1 PF12717.7 EAQ91112.1 - 2.1e-08 34.4 0.1 0.036 14.1 0.0 5.4 6 0 0 6 6 6 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 EAQ91112.1 - 1.5e-06 28.7 0.2 0.014 15.9 0.0 4.5 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 EAQ91112.1 - 0.00025 20.7 0.1 0.92 9.0 0.0 4.5 3 1 0 3 3 3 1 CLASP N terminal HEAT_EZ PF13513.6 EAQ91112.1 - 0.011 16.2 24.0 0.66 10.6 0.5 8.5 8 1 1 9 9 9 0 HEAT-like repeat RT_RNaseH PF17917.1 EAQ91112.1 - 0.07 13.4 0.0 0.28 11.5 0.0 2.0 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase DUF1640 PF07798.11 EAQ91113.1 - 3.1e-45 154.3 1.9 4.6e-45 153.8 1.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) Abhydrolase_6 PF12697.7 EAQ91114.1 - 1.4e-13 52.0 0.8 2.3e-13 51.3 0.8 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DSPc PF00782.20 EAQ91114.1 - 2e-09 37.4 0.0 3.2e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Abhydrolase_1 PF00561.20 EAQ91114.1 - 3.2e-09 36.8 0.0 1.6e-07 31.2 0.0 2.3 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EAQ91114.1 - 2.3e-08 33.6 0.0 1.4e-06 27.7 0.0 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 LIDHydrolase PF10230.9 EAQ91114.1 - 0.0085 15.7 0.0 0.013 15.0 0.0 1.2 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Lipase_3 PF01764.25 EAQ91114.1 - 0.021 14.7 0.0 0.041 13.8 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Y_phosphatase PF00102.27 EAQ91114.1 - 0.051 13.1 0.0 0.078 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase LCAT PF02450.15 EAQ91114.1 - 0.054 12.7 0.0 0.087 12.0 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase PGAP1 PF07819.13 EAQ91114.1 - 0.085 12.6 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein DUF900 PF05990.12 EAQ91114.1 - 0.19 11.2 0.0 0.3 10.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Alk_phosphatase PF00245.20 EAQ91115.1 - 2e-85 287.3 0.0 5.3e-82 276.0 0.0 2.1 1 1 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 EAQ91115.1 - 7.8e-05 22.2 0.0 0.00015 21.3 0.0 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily zf-C2H2_9 PF16293.5 EAQ91115.1 - 0.13 12.1 0.0 0.32 10.9 0.0 1.6 1 0 0 1 1 1 0 C2H2 type zinc-finger (1 copy) Fructosamin_kin PF03881.14 EAQ91117.1 - 0.0013 18.0 0.0 0.0024 17.2 0.0 1.4 1 0 0 1 1 1 1 Fructosamine kinase LRR_9 PF14580.6 EAQ91118.1 - 0.015 14.8 0.2 0.064 12.7 0.1 2.1 2 0 0 2 2 2 0 Leucine-rich repeat U3_assoc_6 PF08640.11 EAQ91118.1 - 0.097 12.7 0.1 0.25 11.4 0.1 1.8 1 0 0 1 1 1 0 U3 small nucleolar RNA-associated protein 6 DUF4138 PF13595.6 EAQ91118.1 - 0.19 11.0 0.0 0.44 9.8 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4138) Rad9 PF04139.13 EAQ91119.1 - 3.9e-36 124.8 2.0 2.1e-24 86.3 0.0 2.1 1 1 1 2 2 2 2 Rad9 Rad1 PF02144.16 EAQ91119.1 - 0.026 13.6 0.3 0.051 12.6 0.3 1.5 1 1 0 1 1 1 0 Repair protein Rad1/Rec1/Rad17 RCC1 PF00415.18 EAQ91120.1 - 1.5e-09 38.3 0.7 3e-08 34.1 0.0 2.2 2 1 0 2 2 2 1 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EAQ91120.1 - 0.00053 19.7 3.1 0.00078 19.2 0.2 2.3 2 0 0 2 2 2 1 Regulator of chromosome condensation (RCC1) repeat PDH PF02153.17 EAQ91121.1 - 1.6e-14 53.5 0.0 2.2e-14 53.1 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase Aminotran_5 PF00266.19 EAQ91122.1 - 1.6e-08 33.9 0.0 4.7e-08 32.4 0.0 1.7 2 0 0 2 2 2 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 EAQ91122.1 - 0.0034 16.0 0.0 0.013 14.0 0.0 1.6 1 1 1 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 EAQ91122.1 - 0.0037 16.6 0.7 0.0064 15.9 0.7 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family DUF222 PF02720.17 EAQ91123.1 - 0.1 12.1 0.2 1.5 8.3 0.2 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF222) ELFV_dehydrog PF00208.21 EAQ91124.1 - 2e-30 106.3 0.0 7.7e-25 88.0 0.0 2.4 2 0 0 2 2 2 2 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 EAQ91124.1 - 2.7e-15 55.0 0.0 5e-15 54.2 0.0 1.4 2 0 0 2 2 2 1 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.18 EAQ91124.1 - 0.00027 20.8 0.0 0.0017 18.2 0.0 2.2 2 0 0 2 2 2 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain DUF1325 PF07039.11 EAQ91124.1 - 0.13 12.3 0.1 1.7 8.8 0.0 2.8 3 0 0 3 3 3 0 SGF29 tudor-like domain Ribosomal_L32e PF01655.18 EAQ91127.1 - 1.3e-50 170.3 0.9 1.3e-50 170.3 0.9 1.4 2 0 0 2 2 2 1 Ribosomal protein L32 DnaJ_C PF01556.18 EAQ91128.1 - 8.4e-23 81.1 0.0 1.2e-22 80.6 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EAQ91128.1 - 3e-22 78.5 3.8 5e-22 77.8 3.8 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EAQ91128.1 - 9.4e-14 51.5 15.6 1.4e-13 51.0 15.6 1.2 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 EAQ91128.1 - 0.076 13.0 12.3 0.093 12.7 1.1 3.0 2 1 1 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 EAQ91128.1 - 0.25 11.4 6.9 3.1 7.9 0.9 2.3 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Cytochrome_C7 PF14522.6 EAQ91128.1 - 0.59 10.2 5.2 1.7 8.7 0.4 2.3 2 0 0 2 2 2 0 Cytochrome c7 and related cytochrome c TackOD1 PF18551.1 EAQ91128.1 - 0.65 9.6 6.9 3.2 7.4 1.3 2.3 1 1 0 2 2 2 0 Thaumarchaeal output domain 1 DZR PF12773.7 EAQ91128.1 - 2.3 8.3 8.3 7.7 6.6 1.3 2.3 2 0 0 2 2 2 0 Double zinc ribbon zf-RING_10 PF16685.5 EAQ91128.1 - 3.9 7.7 8.5 7.4 6.8 1.5 2.3 2 0 0 2 2 2 0 zinc RING finger of MSL2 tRNA-synt_1c PF00749.21 EAQ91129.1 - 1.3e-43 149.2 0.0 4e-41 140.9 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (E and Q), catalytic domain tRNA_bind_3 PF17176.4 EAQ91129.1 - 0.059 13.7 0.0 0.14 12.5 0.0 1.6 1 0 0 1 1 1 0 tRNA-binding domain Fmp27 PF10344.9 EAQ91130.1 - 2.7e-257 856.3 0.0 4.6e-257 855.5 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial protein from FMP27 Apt1 PF10351.9 EAQ91130.1 - 5.9e-199 661.9 0.2 5.9e-199 661.9 0.2 2.7 3 0 0 3 3 2 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.9 EAQ91130.1 - 2.8e-185 616.8 0.0 5.6e-185 615.8 0.0 1.5 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Fmp27_GFWDK PF10347.9 EAQ91130.1 - 5e-58 195.6 0.0 1.1e-57 194.5 0.0 1.7 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.9 EAQ91130.1 - 4.3e-53 179.4 0.1 9.1e-53 178.3 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.9 EAQ91130.1 - 3.8e-31 107.8 0.1 1.3e-30 106.1 0.1 2.0 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain JAB PF01398.21 EAQ91130.1 - 2.9e-27 95.0 0.0 6e-27 94.0 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease CSN5_C PF18323.1 EAQ91130.1 - 2.7e-16 60.3 0.0 3.6e-15 56.6 0.0 3.1 2 0 0 2 2 2 1 Cop9 signalosome subunit 5 C-terminal domain Prok-JAB PF14464.6 EAQ91130.1 - 0.00054 19.7 0.0 0.0014 18.4 0.0 1.7 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Serine_rich PF08824.10 EAQ91130.1 - 0.064 13.3 0.5 0.23 11.4 0.1 2.2 2 0 0 2 2 2 0 Serine rich protein interaction domain LIN37 PF15306.6 EAQ91130.1 - 0.12 12.6 0.4 0.58 10.4 0.4 2.2 1 0 0 1 1 1 0 LIN37 DUF3431 PF11913.8 EAQ91131.1 - 1.3e-78 263.7 0.0 1.6e-78 263.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) RRM_1 PF00076.22 EAQ91133.1 - 3e-08 33.4 0.1 7.8e-08 32.0 0.1 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Asp-B-Hydro_N PF05279.11 EAQ91133.1 - 0.69 9.9 18.1 1 9.4 18.1 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Borrelia_P83 PF05262.11 EAQ91133.1 - 1.2 7.6 16.4 1.6 7.1 16.4 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein GTP_EFTU PF00009.27 EAQ91134.1 - 1e-44 152.4 0.0 1.8e-44 151.6 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 EAQ91134.1 - 9.1e-14 51.3 0.0 2.1e-13 50.1 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EAQ91134.1 - 2e-10 40.9 0.0 5.5e-10 39.5 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 EAQ91134.1 - 1.7e-06 28.0 0.0 3.7e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.18 EAQ91134.1 - 0.00035 20.4 0.0 0.0038 17.0 0.0 2.6 3 0 0 3 3 3 1 Elongation factor G, domain IV Paf67 PF10255.9 EAQ91135.1 - 1.4e-155 518.3 0.0 1.6e-155 518.1 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.17 EAQ91135.1 - 0.0011 18.9 0.1 0.15 12.2 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat Rubredoxin PF00301.20 EAQ91136.1 - 0.066 13.2 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Rubredoxin Usp PF00582.26 EAQ91137.1 - 1.9e-12 47.9 1.3 1.9e-11 44.7 0.0 2.8 3 1 0 3 3 3 1 Universal stress protein family PIF1 PF05970.14 EAQ91138.1 - 5.8e-29 101.4 0.0 3.2e-22 79.2 0.0 2.5 3 0 0 3 3 3 2 PIF1-like helicase AAA_30 PF13604.6 EAQ91138.1 - 1.4e-10 41.2 0.0 3.7e-10 39.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 EAQ91138.1 - 0.00016 21.5 0.1 0.00075 19.3 0.0 2.2 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 EAQ91138.1 - 0.00018 21.9 0.0 0.00041 20.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain Herpes_Helicase PF02689.14 EAQ91138.1 - 0.0027 15.7 0.0 0.004 15.2 0.0 1.1 1 0 0 1 1 1 1 Helicase zf-RING_7 PF02591.15 EAQ91138.1 - 1.1 9.6 2.8 32 4.8 0.0 3.2 3 0 0 3 3 3 0 C4-type zinc ribbon domain ABA_GPCR PF12430.8 EAQ91140.1 - 3.1e-60 203.0 0.0 4.1e-60 202.6 0.0 1.2 1 0 0 1 1 1 1 Abscisic acid G-protein coupled receptor GPHR_N PF12537.8 EAQ91140.1 - 8.1e-15 54.7 1.0 1.3e-13 50.8 0.0 2.7 3 0 0 3 3 3 1 The Golgi pH Regulator (GPHR) Family N-terminal NACHT_N PF17100.5 EAQ91141.1 - 3.3e-72 242.9 0.0 5.8e-38 131.0 0.2 2.3 1 1 1 2 2 2 2 N-terminal domain of NWD NACHT-NTPase NACHT PF05729.12 EAQ91141.1 - 1.6e-11 44.4 0.2 3.4e-11 43.3 0.2 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EAQ91141.1 - 0.012 16.0 0.0 0.032 14.6 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain ResIII PF04851.15 EAQ91141.1 - 0.035 14.1 0.0 0.062 13.3 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TsaE PF02367.17 EAQ91141.1 - 0.052 13.6 0.0 0.24 11.4 0.0 2.0 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 EAQ91141.1 - 0.13 12.0 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 EAQ91141.1 - 0.16 11.2 0.0 0.26 10.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Transferase PF02458.15 EAQ91142.1 - 1.8e-13 50.0 0.0 2.2e-13 49.7 0.0 1.0 1 0 0 1 1 1 1 Transferase family AAA_13 PF13166.6 EAQ91143.1 - 0.00052 18.8 2.1 0.00052 18.8 2.1 1.6 2 0 0 2 2 2 1 AAA domain BRE1 PF08647.11 EAQ91143.1 - 0.0013 18.8 3.7 0.0032 17.5 3.7 1.7 1 0 0 1 1 1 1 BRE1 E3 ubiquitin ligase zf-CCHC PF00098.23 EAQ91143.1 - 0.0026 17.7 0.1 0.0057 16.7 0.1 1.6 1 0 0 1 1 1 1 Zinc knuckle ATG16 PF08614.11 EAQ91143.1 - 0.0096 16.2 9.3 0.026 14.8 9.3 1.7 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) SlyX PF04102.12 EAQ91143.1 - 0.012 16.3 5.7 0.21 12.2 0.7 2.9 1 1 1 2 2 2 0 SlyX HAP1_N PF04849.13 EAQ91143.1 - 0.014 14.6 7.2 0.025 13.8 7.2 1.3 1 0 0 1 1 1 0 HAP1 N-terminal conserved region Vps54_N PF10475.9 EAQ91143.1 - 0.02 14.2 0.3 0.035 13.4 0.3 1.3 1 0 0 1 1 1 0 Vacuolar-sorting protein 54, of GARP complex Taxilin PF09728.9 EAQ91143.1 - 0.022 13.9 5.3 5.2 6.2 0.0 2.5 2 1 0 2 2 2 0 Myosin-like coiled-coil protein DivIC PF04977.15 EAQ91143.1 - 0.028 14.2 2.0 0.15 11.8 0.1 2.7 1 1 1 2 2 2 0 Septum formation initiator Jnk-SapK_ap_N PF09744.9 EAQ91143.1 - 0.033 14.4 0.9 0.076 13.2 0.9 1.5 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Retrotrans_gag PF03732.17 EAQ91143.1 - 0.043 14.1 0.5 0.6 10.4 0.0 2.9 2 0 0 2 2 2 0 Retrotransposon gag protein zf-CCHC_2 PF13696.6 EAQ91143.1 - 0.048 13.5 0.4 0.083 12.7 0.4 1.4 1 0 0 1 1 1 0 Zinc knuckle Spc7 PF08317.11 EAQ91143.1 - 0.053 12.4 5.5 0.11 11.4 5.5 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein Baculo_PEP_C PF04513.12 EAQ91143.1 - 0.082 13.0 2.5 0.28 11.2 2.5 1.9 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus U3_assoc_6 PF08640.11 EAQ91143.1 - 0.11 12.5 0.8 0.25 11.4 0.8 1.5 1 0 0 1 1 1 0 U3 small nucleolar RNA-associated protein 6 FAM76 PF16046.5 EAQ91143.1 - 0.13 11.6 3.8 0.12 11.7 2.2 1.8 2 0 0 2 2 2 0 FAM76 protein DUF5082 PF16888.5 EAQ91143.1 - 0.16 12.2 5.4 0.12 12.6 1.2 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF5082) DUF724 PF05266.14 EAQ91143.1 - 0.22 11.3 2.5 0.42 10.4 2.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) ABC_tran_CTD PF16326.5 EAQ91143.1 - 0.45 10.8 8.3 0.4 11.0 1.8 3.1 2 1 0 3 3 3 0 ABC transporter C-terminal domain UPF0242 PF06785.11 EAQ91143.1 - 0.46 10.6 6.1 0.36 10.9 2.4 2.1 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF1664 PF07889.12 EAQ91143.1 - 0.47 10.5 2.6 0.99 9.5 2.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF4200 PF13863.6 EAQ91143.1 - 0.78 10.1 5.4 2.5 8.5 5.4 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) TMF_DNA_bd PF12329.8 EAQ91143.1 - 0.81 9.7 10.1 1.6 8.8 1.1 3.4 3 1 1 4 4 4 0 TATA element modulatory factor 1 DNA binding DUF4201 PF13870.6 EAQ91143.1 - 1.3 8.7 7.1 0.2 11.4 2.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) Snapin_Pallidin PF14712.6 EAQ91143.1 - 3.4 8.1 5.9 2.5 8.6 1.0 3.0 3 1 0 3 3 2 0 Snapin/Pallidin Syntaxin-6_N PF09177.11 EAQ91143.1 - 3.5 8.3 9.0 1.1e+02 3.4 7.0 3.2 2 1 0 2 2 2 0 Syntaxin 6, N-terminal HalX PF08663.10 EAQ91143.1 - 6 7.3 9.7 1.5 9.2 2.5 2.7 1 1 1 2 2 2 0 HalX domain RT_RNaseH PF17917.1 EAQ91144.1 - 4.5e-37 126.5 0.1 9.4e-37 125.5 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 EAQ91144.1 - 1.4e-34 118.1 0.0 3.4e-34 116.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 EAQ91144.1 - 4.9e-26 91.6 0.0 1.2e-25 90.4 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 EAQ91144.1 - 5.5e-14 52.0 0.0 1.7e-13 50.4 0.0 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 EAQ91144.1 - 7.4e-10 39.0 0.2 2.7e-09 37.2 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.24 EAQ91144.1 - 3.7e-08 33.2 2.5 9e-08 31.9 2.5 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 EAQ91144.1 - 0.014 15.6 0.0 0.045 14.0 0.0 1.8 1 0 0 1 1 1 0 H2C2 zinc finger IN_DBD_C PF00552.21 EAQ91144.1 - 0.27 10.6 2.3 0.31 10.4 0.1 2.2 2 0 0 2 2 2 0 Integrase DNA binding domain SOG2 PF10428.9 EAQ91145.1 - 7 5.7 13.4 8.1 5.5 13.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein p450 PF00067.22 EAQ91147.1 - 3.3e-20 72.3 0.0 5.3e-20 71.6 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 PspC PF04024.12 EAQ91147.1 - 0.16 11.8 1.9 0.48 10.3 1.9 1.8 1 0 0 1 1 1 0 PspC domain EF-hand_4 PF12763.7 EAQ91148.1 - 0.001 19.0 0.0 0.002 18.0 0.0 1.4 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand YSIRK_signal PF04650.17 EAQ91148.1 - 6.6 6.7 5.6 12 5.8 5.6 1.4 1 0 0 1 1 1 0 YSIRK type signal peptide MAP65_ASE1 PF03999.12 EAQ91149.1 - 5.9e-69 233.3 27.5 1.3e-68 232.2 23.1 2.4 1 1 0 2 2 2 2 Microtubule associated protein (MAP65/ASE1 family) Prominin PF05478.11 EAQ91149.1 - 1.2 7.0 2.3 17 3.2 0.1 2.3 3 0 0 3 3 3 0 Prominin XhlA PF10779.9 EAQ91149.1 - 4.4 7.6 4.9 1.2 9.4 0.7 2.2 2 0 0 2 2 2 0 Haemolysin XhlA S1 PF00575.23 EAQ91152.1 - 1.4e-79 262.5 32.3 8.8e-15 54.8 0.2 13.3 13 0 0 13 13 13 11 S1 RNA binding domain S1_2 PF13509.6 EAQ91152.1 - 0.00029 20.8 0.5 48 4.1 0.0 5.3 4 0 0 4 4 4 0 S1 domain RNase_II_C_S1 PF18614.1 EAQ91152.1 - 0.00046 20.1 8.7 0.51 10.3 0.1 5.5 4 1 0 4 4 4 1 RNase II-type exonuclease C-terminal S1 domain ID PF18543.1 EAQ91152.1 - 0.0017 18.4 0.1 0.5 10.4 0.0 3.6 3 0 0 3 3 3 1 Intracellular delivery domain NRDE-2 PF08424.10 EAQ91152.1 - 0.017 14.3 0.4 0.28 10.3 0.1 2.3 2 0 0 2 2 2 0 NRDE-2, necessary for RNA interference TPR_14 PF13428.6 EAQ91152.1 - 0.026 15.3 2.0 52 5.0 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Suf PF05843.14 EAQ91152.1 - 0.13 12.2 10.0 0.1 12.5 1.8 3.1 2 1 1 3 3 3 0 Suppressor of forked protein (Suf) PCB_OB PF17092.5 EAQ91152.1 - 0.54 11.0 19.0 59 4.5 0.0 8.5 6 2 2 9 9 9 0 Penicillin-binding protein OB-like domain DUF2187 PF09953.9 EAQ91152.1 - 0.65 10.0 3.8 17 5.5 0.1 4.2 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2187) Peptidase_M16_C PF05193.21 EAQ91154.1 - 5.1e-59 199.4 0.0 8.6e-59 198.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EAQ91154.1 - 3e-41 140.9 0.0 4.9e-41 140.2 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) FHA PF00498.26 EAQ91155.1 - 5.2e-16 58.7 0.0 1e-15 57.8 0.0 1.5 1 0 0 1 1 1 1 FHA domain zf-RING_11 PF17123.5 EAQ91155.1 - 5e-08 32.5 3.0 8.6e-08 31.8 3.0 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 EAQ91155.1 - 0.0017 18.6 6.6 0.0029 17.9 6.6 1.4 1 0 0 1 1 1 1 Ring finger domain Yop-YscD_cpl PF16697.5 EAQ91155.1 - 0.016 15.6 0.0 0.032 14.5 0.0 1.4 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain zf-C3HC4 PF00097.25 EAQ91155.1 - 0.07 13.0 5.8 0.13 12.2 5.8 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EAQ91155.1 - 0.13 12.6 5.9 0.23 11.8 5.9 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_5 PF14634.6 EAQ91155.1 - 0.54 10.3 4.3 0.97 9.5 4.3 1.4 1 0 0 1 1 1 0 zinc-RING finger domain PHD PF00628.29 EAQ91155.1 - 1 9.3 3.7 2 8.4 3.7 1.5 1 0 0 1 1 1 0 PHD-finger zf-C3HC4_2 PF13923.6 EAQ91155.1 - 1.8 8.4 7.8 3.5 7.5 7.8 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Vps16_N PF04841.13 EAQ91156.1 - 4.5e-92 308.9 0.0 5.6e-92 308.6 0.0 1.1 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.12 EAQ91156.1 - 9.9e-79 264.7 0.0 1.4e-78 264.2 0.0 1.1 1 0 0 1 1 1 1 Vps16, C-terminal region ANAPC4_WD40 PF12894.7 EAQ91156.1 - 0.0034 17.7 0.0 0.19 12.0 0.0 2.6 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain ACR_tran PF00873.19 EAQ91156.1 - 0.12 10.0 0.0 0.16 9.6 0.0 1.1 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family ATG16 PF08614.11 EAQ91157.1 - 6.9e-54 183.1 14.1 7.7e-54 183.0 14.1 1.0 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) DUF4201 PF13870.6 EAQ91157.1 - 0.00042 20.1 10.6 0.00075 19.3 10.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) YjbH PF06082.11 EAQ91157.1 - 0.049 12.4 4.1 0.055 12.3 4.1 1.0 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH DUF2461 PF09365.10 EAQ91157.1 - 0.18 11.8 3.4 0.27 11.2 3.4 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein (DUF2461) UPF0242 PF06785.11 EAQ91157.1 - 0.28 11.3 15.7 7.1 6.7 2.9 2.9 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus GAS PF13851.6 EAQ91157.1 - 0.61 9.4 18.0 0.081 12.3 13.9 1.6 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding YabA PF06156.13 EAQ91157.1 - 2.1 9.1 11.4 14 6.4 1.6 3.1 2 1 1 3 3 3 0 Initiation control protein YabA ZapB PF06005.12 EAQ91157.1 - 4.8 7.7 23.2 0.9 10.0 3.3 3.6 2 1 0 3 3 3 0 Cell division protein ZapB APG6_N PF17675.1 EAQ91157.1 - 6.6 7.3 22.8 1.2 9.7 6.6 2.9 2 1 1 3 3 3 0 Apg6 coiled-coil region DOT1 PF08123.13 EAQ91158.1 - 4.2e-73 245.3 0.0 5.8e-73 244.8 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_31 PF13847.6 EAQ91158.1 - 0.005 16.6 0.1 0.0081 16.0 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAQ91158.1 - 0.039 14.7 0.0 0.076 13.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Pkinase PF00069.25 EAQ91159.1 - 1.7e-19 70.2 0.0 4.7e-18 65.5 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ91159.1 - 3.1e-08 33.2 0.0 7.2e-08 32.0 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase FHA PF00498.26 EAQ91159.1 - 0.11 12.9 0.0 0.25 11.7 0.0 1.6 1 0 0 1 1 1 0 FHA domain CHIP_TPR_N PF18391.1 EAQ91159.1 - 1.7 9.5 5.4 0.32 11.8 0.3 2.3 2 0 0 2 2 2 0 CHIP N-terminal tetratricopeptide repeat domain DUF4449 PF14613.6 EAQ91161.1 - 2.3e-66 222.9 0.3 2.3e-66 222.9 0.3 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) Prp18 PF02840.15 EAQ91161.1 - 0.051 13.6 2.8 0.75 9.8 0.0 2.8 2 1 1 3 3 3 0 Prp18 domain DNA_ligase_A_M PF01068.21 EAQ91162.1 - 1.1e-45 155.8 0.0 2.9e-45 154.4 0.0 1.7 2 0 0 2 2 2 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 EAQ91162.1 - 3.3e-37 128.5 0.0 6.3e-37 127.6 0.0 1.4 1 0 0 1 1 1 1 DNA ligase N terminus BRCT_2 PF16589.5 EAQ91162.1 - 1.9e-17 63.5 0.0 5.1e-09 36.4 0.0 2.5 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain RNA_ligase PF09414.10 EAQ91162.1 - 3.5e-16 59.9 0.0 7.2e-16 58.9 0.0 1.5 1 0 0 1 1 1 1 RNA ligase DNA_ligase_A_C PF04679.15 EAQ91162.1 - 3.5e-15 56.4 0.6 2.6e-14 53.6 0.0 2.6 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region BRCT PF00533.26 EAQ91162.1 - 1.8e-07 31.5 0.1 2.1e-06 28.0 0.1 2.4 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 EAQ91162.1 - 0.00019 21.7 0.0 0.77 10.1 0.0 2.8 2 0 0 2 2 2 2 DNA ligase 3 BRCT domain DNA_ligase_IV PF11411.8 EAQ91162.1 - 0.0021 18.1 0.2 0.0049 17.0 0.2 1.6 1 0 0 1 1 1 1 DNA ligase IV RTT107_BRCT_5 PF16770.5 EAQ91162.1 - 0.051 13.5 0.0 4 7.4 0.0 2.5 2 0 0 2 2 2 0 Regulator of Ty1 transposition protein 107 BRCT domain mRNA_cap_enzyme PF01331.19 EAQ91162.1 - 0.057 13.2 0.1 1.9 8.3 0.1 2.6 1 1 0 1 1 1 0 mRNA capping enzyme, catalytic domain UPRTase PF14681.6 EAQ91163.1 - 3.7e-73 245.4 0.0 4.2e-73 245.2 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 EAQ91163.1 - 0.00043 19.8 0.1 0.00084 18.9 0.1 1.6 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Pribosyl_synth PF14572.6 EAQ91163.1 - 0.024 14.7 0.0 0.038 14.0 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl synthetase-associated domain tRNA-synt_1g PF09334.11 EAQ91164.1 - 2.9e-105 352.2 0.5 8.4e-75 251.9 0.5 2.8 1 1 1 2 2 2 2 tRNA synthetases class I (M) CRCB PF02537.15 EAQ91164.1 - 1.1e-29 102.5 14.7 3.1e-20 72.3 13.0 2.5 2 0 0 2 2 2 2 CrcB-like protein, Camphor Resistance (CrcB) tRNA-synt_1 PF00133.22 EAQ91164.1 - 0.19 10.0 6.3 13 3.9 0.0 3.9 4 1 1 5 5 5 0 tRNA synthetases class I (I, L, M and V) SIN1 PF05422.12 EAQ91164.1 - 3 8.4 6.3 0.43 11.1 0.2 2.1 2 0 0 2 2 2 0 Stress-activated map kinase interacting protein 1 (SIN1) Lactamase_B PF00753.27 EAQ91165.1 - 1.7e-06 28.2 0.0 2.8e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EAQ91165.1 - 0.0012 18.4 0.0 0.0019 17.7 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DUF4551 PF15087.6 EAQ91165.1 - 0.026 13.4 3.9 0.028 13.3 3.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) RMMBL PF07521.12 EAQ91165.1 - 0.093 12.7 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Zn-dependent metallo-hydrolase RNA specificity domain TMEM174 PF15029.6 EAQ91165.1 - 0.59 9.8 2.3 0.91 9.2 2.3 1.2 1 0 0 1 1 1 0 Transmembrane protein 174 Tim54 PF11711.8 EAQ91165.1 - 9.8 4.8 8.6 15 4.2 8.6 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 ketoacyl-synt PF00109.26 EAQ91166.1 - 1.6e-73 247.4 0.2 3.8e-73 246.2 0.0 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 EAQ91166.1 - 9.5e-61 204.8 0.0 2.1e-60 203.7 0.0 1.7 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 EAQ91166.1 - 7.5e-52 176.4 0.0 1.3e-51 175.6 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 EAQ91166.1 - 1.4e-39 136.5 0.5 1.4e-34 120.1 0.5 2.6 1 1 1 2 2 2 2 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EAQ91166.1 - 4.2e-35 120.3 0.9 1.1e-34 119.0 0.3 2.2 2 0 0 2 2 1 1 Beta-ketoacyl synthase, C-terminal domain MFS_1 PF07690.16 EAQ91166.1 - 2e-31 109.2 45.3 4.6e-31 108.0 45.3 1.7 1 0 0 1 1 1 1 Major Facilitator Superfamily ADH_zinc_N_2 PF13602.6 EAQ91166.1 - 3.2e-18 67.0 0.0 2.4e-17 64.2 0.0 2.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EAQ91166.1 - 6.6e-17 61.7 0.0 4.7e-16 59.0 0.0 2.4 2 0 0 2 2 2 1 Zinc-binding dehydrogenase KAsynt_C_assoc PF16197.5 EAQ91166.1 - 1.5e-15 57.6 0.0 8.3e-15 55.2 0.0 2.3 2 1 0 2 2 1 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 EAQ91166.1 - 4.4e-09 36.1 0.0 2.5e-08 33.6 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase PP-binding PF00550.25 EAQ91166.1 - 1.1e-06 28.9 0.1 3.4e-06 27.3 0.1 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_12 PF08242.12 EAQ91166.1 - 5.2e-06 27.1 0.0 2.1e-05 25.2 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAQ91166.1 - 2.9e-05 23.9 0.0 6.3e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain adh_short_C2 PF13561.6 EAQ91166.1 - 6.8e-05 22.5 0.0 0.00026 20.6 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Methyltransf_23 PF13489.6 EAQ91166.1 - 0.00014 21.7 0.0 0.00031 20.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EAQ91166.1 - 0.00019 22.0 0.0 0.0007 20.2 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAQ91166.1 - 0.0032 18.1 0.0 0.07 13.8 0.0 3.1 3 0 0 3 3 2 1 Methyltransferase domain ADH_N PF08240.12 EAQ91166.1 - 0.0035 17.2 0.2 0.009 15.9 0.2 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Thiolase_N PF00108.23 EAQ91166.1 - 0.0093 15.4 0.1 0.02 14.3 0.1 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Sacchrp_dh_NADP PF03435.18 EAQ91166.1 - 0.065 13.5 0.3 0.47 10.7 0.0 2.6 3 0 0 3 3 3 0 Saccharopine dehydrogenase NADP binding domain FSH1 PF03959.13 EAQ91167.1 - 5.1e-27 94.9 0.0 4.5e-21 75.5 0.0 2.1 2 0 0 2 2 2 2 Serine hydrolase (FSH1) DUF959 PF06121.14 EAQ91167.1 - 0.031 14.5 2.2 0.46 10.7 0.0 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF959) Abhydrolase_2 PF02230.16 EAQ91167.1 - 0.094 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase RPE65 PF03055.15 EAQ91168.1 - 4.8e-108 362.3 0.0 7.8e-108 361.6 0.0 1.3 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Zn_clus PF00172.18 EAQ91168.1 - 4.8e-05 23.4 6.7 0.00011 22.2 6.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CFEM PF05730.11 EAQ91169.1 - 1e-11 44.7 7.8 1e-11 44.7 7.8 1.6 2 0 0 2 2 2 1 CFEM domain YjeF_N PF03853.15 EAQ91171.1 - 5.3e-46 156.6 0.0 7.8e-46 156.1 0.0 1.2 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.10 EAQ91171.1 - 1.5e-09 38.7 0.3 3.5e-09 37.5 0.0 1.8 2 0 0 2 2 2 1 FDF domain PIF1 PF05970.14 EAQ91172.1 - 3.4e-52 177.8 0.3 2.2e-43 148.8 0.0 2.2 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 EAQ91172.1 - 1.4e-19 70.6 0.0 2.5e-19 69.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAQ91172.1 - 1.9e-12 47.7 0.0 4.1e-12 46.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EAQ91172.1 - 6.2e-07 29.8 0.0 3.4e-06 27.4 0.0 2.2 1 1 1 2 2 2 1 AAA domain AAA PF00004.29 EAQ91172.1 - 2.4e-05 24.8 0.4 8.3e-05 23.0 0.1 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 EAQ91172.1 - 5.5e-05 22.8 0.1 0.00015 21.3 0.0 1.7 2 0 0 2 2 1 1 P-loop containing dynein motor region Herpes_Helicase PF02689.14 EAQ91172.1 - 6.9e-05 21.0 0.1 0.00033 18.8 0.0 1.8 2 0 0 2 2 2 1 Helicase UvrD_C_2 PF13538.6 EAQ91172.1 - 0.00014 21.6 0.1 0.0011 18.8 0.0 2.3 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_16 PF13191.6 EAQ91172.1 - 0.00014 22.3 0.0 0.00054 20.4 0.0 2.1 2 0 0 2 2 1 1 AAA ATPase domain ABC_tran PF00005.27 EAQ91172.1 - 0.001 19.6 0.1 0.003 18.1 0.1 1.8 1 0 0 1 1 1 1 ABC transporter Viral_helicase1 PF01443.18 EAQ91172.1 - 0.0042 16.9 0.0 3.1 7.5 0.0 2.6 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.22 EAQ91172.1 - 0.0057 17.0 0.0 0.014 15.8 0.0 1.6 1 0 0 1 1 1 1 RNA helicase NACHT PF05729.12 EAQ91172.1 - 0.0059 16.5 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_11 PF13086.6 EAQ91172.1 - 0.0074 16.1 1.5 0.027 14.3 0.0 2.5 2 1 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EAQ91172.1 - 0.0096 15.8 0.1 0.019 14.9 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase NB-ARC PF00931.22 EAQ91172.1 - 0.012 14.8 0.1 0.02 14.1 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_29 PF13555.6 EAQ91172.1 - 0.012 15.3 0.0 0.034 13.9 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain T2SSE PF00437.20 EAQ91172.1 - 0.014 14.5 0.1 0.024 13.7 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_14 PF13173.6 EAQ91172.1 - 0.016 15.3 0.0 0.047 13.7 0.0 1.8 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAQ91172.1 - 0.021 14.3 0.0 0.055 12.9 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein IstB_IS21 PF01695.17 EAQ91172.1 - 0.028 14.2 0.0 0.15 11.8 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein ATPase_2 PF01637.18 EAQ91172.1 - 0.03 14.2 0.1 0.089 12.7 0.0 1.9 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea Helicase_RecD PF05127.14 EAQ91172.1 - 0.033 14.0 0.0 0.092 12.6 0.0 1.7 1 0 0 1 1 1 0 Helicase AAA_5 PF07728.14 EAQ91172.1 - 0.039 14.0 0.2 0.48 10.4 0.2 2.4 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 EAQ91172.1 - 0.039 13.6 0.0 0.084 12.6 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain TIP49 PF06068.13 EAQ91172.1 - 0.051 12.8 0.0 2.9 7.0 0.0 2.5 3 0 0 3 3 3 0 TIP49 P-loop domain SH3_13 PF18335.1 EAQ91172.1 - 0.053 13.3 0.0 0.16 11.8 0.0 1.8 1 0 0 1 1 1 0 ATP-dependent RecD-like DNA helicase SH3 domain DUF2075 PF09848.9 EAQ91172.1 - 0.053 12.7 0.1 0.12 11.5 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) TsaE PF02367.17 EAQ91172.1 - 0.061 13.3 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AFG1_ATPase PF03969.16 EAQ91172.1 - 0.062 12.2 0.3 0.31 9.9 0.1 1.9 2 0 0 2 2 2 0 AFG1-like ATPase DUF815 PF05673.13 EAQ91172.1 - 0.083 12.0 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ResIII PF04851.15 EAQ91172.1 - 0.11 12.5 0.1 0.2 11.6 0.1 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit NTPase_1 PF03266.15 EAQ91172.1 - 0.12 12.3 0.2 0.3 11.0 0.0 1.8 2 0 0 2 2 1 0 NTPase CENP-K PF11802.8 EAQ91172.1 - 0.36 10.4 1.2 3.7 7.0 0.4 2.2 2 0 0 2 2 2 0 Centromere-associated protein K Nha1_C PF08619.10 EAQ91173.1 - 1e-135 453.6 24.3 1.2e-135 453.3 24.3 1.1 1 0 0 1 1 1 1 Alkali metal cation/H+ antiporter Nha1 C terminus Na_H_Exchanger PF00999.21 EAQ91173.1 - 6.8e-77 258.8 22.0 8.2e-77 258.5 22.0 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family CstA PF02554.14 EAQ91173.1 - 0.59 9.0 9.5 0.13 11.2 3.3 2.2 2 0 0 2 2 2 0 Carbon starvation protein CstA Ribosomal_60s PF00428.19 EAQ91173.1 - 4 8.1 12.0 2.1 9.0 0.8 2.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein SasG_E PF17041.5 EAQ91174.1 - 7.9 6.6 6.9 0.75 9.9 1.6 2.1 2 0 0 2 2 2 0 E domain PP2C PF00481.21 EAQ91175.1 - 4.3e-62 210.1 0.2 3.4e-51 174.3 0.2 3.1 1 1 1 2 2 2 2 Protein phosphatase 2C Snf7 PF03357.21 EAQ91176.1 - 9e-36 123.1 16.7 9e-36 123.1 16.7 1.3 2 0 0 2 2 2 1 Snf7 RHH_8 PF17723.1 EAQ91176.1 - 0.3 11.3 2.9 0.42 10.8 0.4 2.3 1 1 2 3 3 3 0 Ribbon-Helix-Helix transcriptional regulator family PspA_IM30 PF04012.12 EAQ91176.1 - 2.9 7.4 16.6 0.86 9.1 3.9 2.1 1 1 0 2 2 2 0 PspA/IM30 family GTP_EFTU PF00009.27 EAQ91177.1 - 4.2e-05 23.2 0.8 9.8e-05 22.0 0.6 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 EAQ91177.1 - 5.4e-05 23.3 1.0 0.00016 21.8 0.2 2.1 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 EAQ91177.1 - 0.0018 18.3 0.2 0.0061 16.6 0.2 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase MlaE PF02405.16 EAQ91177.1 - 0.018 14.7 1.1 0.031 13.9 1.1 1.3 1 0 0 1 1 1 0 Permease MlaE DUF1184 PF06683.11 EAQ91177.1 - 0.11 12.0 0.1 0.24 10.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1184) STAT_alpha PF01017.20 EAQ91177.1 - 5.8 6.8 7.4 0.59 10.0 1.3 2.5 4 0 0 4 4 4 0 STAT protein, all-alpha domain A_deaminase PF00962.22 EAQ91178.1 - 3.4e-10 39.8 0.0 0.00053 19.4 0.0 2.2 2 0 0 2 2 2 2 Adenosine/AMP deaminase WD40 PF00400.32 EAQ91179.1 - 2.9e-37 126.0 18.8 2.9e-07 31.1 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAQ91179.1 - 2.8e-14 53.2 0.0 0.00027 21.2 0.1 4.7 1 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EAQ91179.1 - 0.00012 21.2 0.1 0.78 8.6 0.0 3.8 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 EAQ91179.1 - 0.0002 21.3 0.0 0.25 11.2 0.0 2.7 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Phosducin PF02114.16 EAQ91180.1 - 6.8e-10 38.3 0.7 4e-08 32.5 0.7 2.3 1 1 0 1 1 1 1 Phosducin Ran_BP1 PF00638.18 EAQ91182.1 - 1e-47 161.4 0.7 2e-47 160.4 0.7 1.5 1 0 0 1 1 1 1 RanBP1 domain VID27_PH PF17747.1 EAQ91182.1 - 0.014 15.7 0.0 0.02 15.1 0.0 1.3 1 0 0 1 1 1 0 VID27 PH-like domain PS-DH PF14765.6 EAQ91182.1 - 0.016 14.5 0.2 0.03 13.6 0.2 1.4 1 0 0 1 1 1 0 Polyketide synthase dehydratase YEATS PF03366.16 EAQ91183.1 - 1.4e-20 73.1 0.1 2.7e-20 72.1 0.1 1.5 1 0 0 1 1 1 1 YEATS family BET PF17035.5 EAQ91183.1 - 0.0019 18.3 0.4 0.004 17.3 0.4 1.5 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation Baculo_8kDa PF06096.11 EAQ91183.1 - 0.03 14.4 0.0 0.066 13.3 0.0 1.5 1 0 0 1 1 1 0 Baculoviridae 8.2 KDa protein Lin0512_fam PF09585.10 EAQ91183.1 - 0.13 12.3 0.2 0.62 10.1 0.1 1.9 2 0 0 2 2 2 0 Conserved hypothetical protein (Lin0512_fam) Zn_clus PF00172.18 EAQ91184.1 - 6.5e-07 29.4 11.8 1.1e-06 28.7 11.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AMP-binding PF00501.28 EAQ91185.1 - 1.9e-15 56.4 0.3 6.4e-13 48.1 0.1 2.1 2 0 0 2 2 2 2 AMP-binding enzyme ACAS_N PF16177.5 EAQ91185.1 - 3.7e-10 39.6 2.0 1.2e-09 37.9 0.2 2.3 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus Aminotran_1_2 PF00155.21 EAQ91186.1 - 1e-56 192.7 0.0 2.2e-56 191.6 0.0 1.4 2 0 0 2 2 2 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 EAQ91186.1 - 0.018 14.4 0.0 0.08 12.2 0.0 1.7 1 1 0 1 1 1 0 Beta-eliminating lyase Aminotran_5 PF00266.19 EAQ91186.1 - 0.077 11.9 0.0 0.12 11.4 0.0 1.1 1 0 0 1 1 1 0 Aminotransferase class-V DUF4211 PF13926.6 EAQ91187.1 - 7.3e-45 152.6 0.0 2e-44 151.1 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4211) SAM_2 PF07647.17 EAQ91188.1 - 8e-17 61.1 0.0 1.3e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 EAQ91188.1 - 5.9e-15 55.5 0.0 9e-15 54.9 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.23 EAQ91188.1 - 2.4e-11 44.1 0.0 5.8e-11 42.9 0.0 1.6 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SAM_4 PF18017.1 EAQ91188.1 - 0.065 13.2 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) GRAS PF03514.14 EAQ91189.1 - 2.2 7.1 4.7 3.3 6.6 4.7 1.1 1 0 0 1 1 1 0 GRAS domain family adh_short PF00106.25 EAQ91190.1 - 1.2e-34 119.5 0.8 1.6e-34 119.1 0.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EAQ91190.1 - 1.2e-26 93.7 1.2 5.1e-26 91.7 1.2 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EAQ91190.1 - 9.5e-16 58.2 0.5 1.3e-15 57.8 0.5 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EAQ91190.1 - 8.7e-06 25.1 0.0 1.3e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 EAQ91190.1 - 0.00081 18.9 0.2 0.0025 17.3 0.2 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_7 PF13241.6 EAQ91190.1 - 0.027 14.9 0.1 0.069 13.6 0.1 1.7 1 1 0 1 1 1 0 Putative NAD(P)-binding ThiF PF00899.21 EAQ91190.1 - 0.047 13.0 0.3 1 8.6 0.1 2.2 2 0 0 2 2 2 0 ThiF family TRAF6_Z2 PF18048.1 EAQ91191.1 - 0.11 12.6 1.5 0.29 11.2 1.5 1.7 1 0 0 1 1 1 0 TNF receptor-associated factor 6 zinc finger 2 Dynamin_N PF00350.23 EAQ91194.1 - 1.1e-18 67.8 0.0 2.1e-18 67.0 0.0 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 EAQ91194.1 - 1.3e-12 47.6 0.0 1.4e-10 40.8 0.0 2.3 2 0 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.23 EAQ91194.1 - 0.00038 20.5 0.0 0.0013 18.8 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 EAQ91194.1 - 0.016 15.6 0.0 0.28 11.6 0.0 2.7 2 0 0 2 2 2 0 AAA ATPase domain FeoB_N PF02421.18 EAQ91194.1 - 0.048 13.2 0.0 3.6 7.1 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_15 PF13175.6 EAQ91194.1 - 0.055 13.2 0.0 0.096 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Clr5 PF14420.6 EAQ91195.1 - 0.038 14.2 0.3 0.12 12.6 0.1 2.0 2 0 0 2 2 2 0 Clr5 domain zf-C2H2 PF00096.26 EAQ91195.1 - 0.25 11.9 4.4 0.15 12.6 1.4 2.3 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF3435 PF11917.8 EAQ91198.1 - 6.5e-30 104.4 0.0 1.5e-23 83.4 0.0 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF3435) Fungal_trans PF04082.18 EAQ91199.1 - 0.023 13.7 0.0 0.025 13.6 0.0 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain AIG1 PF04548.16 EAQ91200.1 - 4.4e-06 26.2 0.0 0.1 11.9 0.0 2.6 2 0 0 2 2 2 2 AIG1 family MMR_HSR1 PF01926.23 EAQ91200.1 - 5.5e-06 26.4 0.6 0.00016 21.7 0.1 3.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EAQ91200.1 - 0.00082 19.3 0.0 0.0028 17.6 0.0 1.9 1 1 0 1 1 1 1 RsgA GTPase DUF4254 PF14063.6 EAQ91200.1 - 0.0023 17.7 0.6 0.0065 16.3 0.6 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF4254) AAA_29 PF13555.6 EAQ91200.1 - 0.0054 16.4 0.0 0.013 15.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 EAQ91200.1 - 0.008 16.6 0.9 0.15 12.4 0.0 3.2 3 1 1 4 4 3 1 AAA ATPase domain AAA_22 PF13401.6 EAQ91200.1 - 0.011 16.0 0.1 0.81 10.0 0.0 3.6 4 0 0 4 4 4 0 AAA domain FtsK_SpoIIIE PF01580.18 EAQ91200.1 - 0.017 14.5 0.0 0.12 11.7 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_13 PF13166.6 EAQ91200.1 - 0.026 13.2 3.8 0.021 13.5 1.9 1.7 2 0 0 2 2 2 0 AAA domain Septin PF00735.18 EAQ91200.1 - 0.032 13.5 0.1 0.13 11.5 0.1 2.0 1 1 0 1 1 1 0 Septin T2SSE PF00437.20 EAQ91200.1 - 0.038 13.0 0.0 0.1 11.7 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_23 PF13476.6 EAQ91200.1 - 0.071 13.6 6.6 0.67 10.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EAQ91200.1 - 0.095 13.1 0.0 0.27 11.7 0.0 1.8 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.27 EAQ91200.1 - 0.11 13.1 0.0 0.59 10.6 0.0 2.3 1 0 0 1 1 1 0 ABC transporter ATPase_2 PF01637.18 EAQ91200.1 - 0.26 11.2 3.3 0.5 10.2 0.0 2.9 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea DUF87 PF01935.17 EAQ91200.1 - 1.9 8.5 3.8 1.8 8.6 0.0 2.6 2 1 0 2 2 2 0 Helicase HerA, central domain Ribosomal_S13 PF00416.22 EAQ91201.1 - 3e-55 186.0 2.0 3.5e-55 185.8 2.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 EAQ91201.1 - 0.01 14.6 0.0 0.012 14.4 0.0 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) HHH_6 PF14579.6 EAQ91201.1 - 0.11 12.7 0.1 0.42 10.9 0.1 1.9 1 1 0 1 1 1 0 Helix-hairpin-helix motif SBDS_C PF09377.10 EAQ91202.1 - 3.1e-46 156.1 0.0 5e-46 155.5 0.0 1.3 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.18 EAQ91202.1 - 1.6e-34 117.8 0.0 2.6e-34 117.1 0.0 1.4 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein Peptidase_S10 PF00450.22 EAQ91203.1 - 3.9e-130 435.0 0.8 4.8e-130 434.7 0.8 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Carbpep_Y_N PF05388.11 EAQ91203.1 - 3.9e-11 43.6 0.0 9.9e-11 42.3 0.0 1.7 1 0 0 1 1 1 1 Carboxypeptidase Y pro-peptide PDEase_I PF00233.19 EAQ91204.1 - 4.5e-66 223.0 0.0 7.2e-66 222.3 0.0 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase UCH PF00443.29 EAQ91205.1 - 1.8e-67 227.5 0.0 2.9e-67 226.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 EAQ91205.1 - 1.1e-11 45.2 0.0 3.8e-11 43.4 0.0 2.0 2 0 0 2 2 2 1 DUSP domain UCH_1 PF13423.6 EAQ91205.1 - 5.7e-11 42.6 0.0 0.0023 17.6 0.0 3.2 3 0 0 3 3 3 3 Ubiquitin carboxyl-terminal hydrolase Zn_ribbon_SprT PF17283.2 EAQ91205.1 - 3.7 7.5 5.1 0.49 10.3 0.9 1.7 2 0 0 2 2 2 0 SprT-like zinc ribbon domain Peptidase_M16_M PF16187.5 EAQ91206.1 - 3.3e-92 308.8 0.0 5.6e-92 308.0 0.0 1.4 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 EAQ91206.1 - 9e-29 100.4 1.2 2.6e-28 98.9 0.1 2.1 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EAQ91206.1 - 2.3e-21 76.7 0.5 1.8e-13 50.9 0.1 3.9 4 0 0 4 4 4 2 Peptidase M16 inactive domain Gemini_AL1_M PF08283.11 EAQ91206.1 - 0.36 10.9 2.8 2.4 8.3 0.3 2.4 2 0 0 2 2 2 0 Geminivirus rep protein central domain MPP6 PF10175.9 EAQ91207.1 - 0.00024 21.6 0.1 0.00024 21.6 0.1 3.2 2 1 0 3 3 3 2 M-phase phosphoprotein 6 zf-CCHC PF00098.23 EAQ91207.1 - 0.0027 17.7 3.7 0.0041 17.1 3.7 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EAQ91207.1 - 0.1 12.4 4.2 0.16 11.8 4.2 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CHCC PF10276.9 EAQ91208.1 - 4.3e-15 55.5 1.5 1.4e-14 53.9 1.1 1.9 2 0 0 2 2 2 1 Zinc-finger domain Methyltransf_31 PF13847.6 EAQ91211.1 - 1.4e-09 37.9 0.0 7.7e-09 35.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAQ91211.1 - 5.8e-08 33.3 0.2 3e-07 31.1 0.1 2.2 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.6 EAQ91211.1 - 2.8e-07 30.5 0.2 7e-07 29.2 0.1 1.8 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EAQ91211.1 - 2.6e-06 28.0 0.1 7.8e-06 26.5 0.1 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EAQ91211.1 - 3.3e-06 27.8 0.0 2.7e-05 24.8 0.1 2.5 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 EAQ91211.1 - 0.00057 19.5 0.0 0.00095 18.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain MetW PF07021.12 EAQ91211.1 - 0.00096 18.8 0.1 0.0015 18.1 0.1 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.6 EAQ91211.1 - 0.0079 16.2 0.0 0.011 15.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain AdoMet_MTase PF07757.13 EAQ91211.1 - 0.009 16.3 0.0 0.014 15.7 0.0 1.3 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Pox_MCEL PF03291.16 EAQ91211.1 - 0.034 13.3 0.0 0.047 12.8 0.0 1.1 1 0 0 1 1 1 0 mRNA capping enzyme HEAT PF02985.22 EAQ91212.1 - 1e-36 121.8 13.9 0.058 13.7 0.0 13.2 14 0 0 14 14 14 10 HEAT repeat HEAT_2 PF13646.6 EAQ91212.1 - 1.2e-30 105.8 9.2 2e-09 37.7 0.0 8.0 4 2 5 9 9 9 9 HEAT repeats Cnd1 PF12717.7 EAQ91212.1 - 3.7e-12 46.6 12.3 1.2e-05 25.4 0.4 6.3 5 1 0 7 7 7 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 EAQ91212.1 - 1.2e-11 45.1 3.4 0.043 14.4 0.0 7.5 4 2 4 8 8 8 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 EAQ91212.1 - 1.9e-11 44.2 7.2 0.016 15.7 0.0 8.4 8 2 2 10 10 9 2 HEAT-like repeat Adaptin_N PF01602.20 EAQ91212.1 - 8.5e-09 34.5 6.6 0.00012 20.7 0.3 4.7 4 1 2 6 6 6 3 Adaptin N terminal region RTP1_C1 PF10363.9 EAQ91212.1 - 1e-06 28.9 3.7 0.03 14.5 0.1 4.7 3 1 2 5 5 5 2 Required for nuclear transport of RNA pol II C-terminus 1 CLASP_N PF12348.8 EAQ91212.1 - 7.4e-05 22.4 1.9 0.88 9.1 0.2 4.5 2 1 1 4 4 4 2 CLASP N terminal DNA_alkylation PF08713.11 EAQ91212.1 - 0.0072 16.1 0.0 6.5 6.4 0.0 3.6 3 1 0 4 4 4 1 DNA alkylation repair enzyme Arm PF00514.23 EAQ91212.1 - 0.0078 16.2 1.5 2.2 8.4 0.0 4.7 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat Proteasom_PSMB PF10508.9 EAQ91212.1 - 0.054 12.0 2.0 0.29 9.6 0.1 2.3 2 0 0 2 2 2 0 Proteasome non-ATPase 26S subunit IFRD PF05004.13 EAQ91212.1 - 0.39 9.8 1.8 2 7.4 0.1 3.0 3 2 0 3 3 3 0 Interferon-related developmental regulator (IFRD) API5 PF05918.11 EAQ91212.1 - 2.4 6.9 6.3 1.3 7.7 0.8 3.3 3 1 1 4 4 4 0 Apoptosis inhibitory protein 5 (API5) Myotub-related PF06602.14 EAQ91213.1 - 1.1e-148 494.9 0.0 1.5e-148 494.4 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.6 EAQ91213.1 - 0.016 15.1 0.0 0.038 14.0 0.0 1.6 1 0 0 1 1 1 0 Tyrosine phosphatase family Interferon PF00143.19 EAQ91213.1 - 0.052 13.7 0.1 0.094 12.9 0.1 1.3 1 0 0 1 1 1 0 Interferon alpha/beta domain Ribosomal_S3_C PF00189.20 EAQ91214.1 - 1e-24 86.9 0.2 5.4e-24 84.5 0.1 2.1 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 EAQ91214.1 - 6.5e-12 45.1 0.1 1.1e-11 44.4 0.1 1.4 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.8 EAQ91214.1 - 0.1 13.1 0.0 0.2 12.2 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Coilin_N PF15862.5 EAQ91214.1 - 0.13 12.1 0.1 0.33 10.8 0.0 1.6 2 0 0 2 2 2 0 Coilin N-terminus Mg_trans_NIPA PF05653.14 EAQ91215.1 - 4.9e-100 334.4 15.8 5.8e-100 334.2 15.8 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 EAQ91215.1 - 5.2e-05 23.4 34.2 6.3e-05 23.2 8.7 3.1 3 0 0 3 3 3 2 EamA-like transporter family DUF4293 PF14126.6 EAQ91215.1 - 1.5 9.1 6.1 3.4 7.9 6.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4293) DUF2420 PF10336.9 EAQ91216.1 - 0.0066 16.5 0.0 0.015 15.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) Adap_comp_sub PF00928.21 EAQ91217.1 - 1.2e-17 64.2 0.0 1.7e-17 63.7 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EAQ91217.1 - 1.1e-07 31.9 0.1 1.7e-07 31.2 0.1 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain RPM2 PF08579.11 EAQ91217.1 - 0.0075 16.7 0.1 0.017 15.5 0.1 1.6 1 0 0 1 1 1 1 Mitochondrial ribonuclease P subunit (RPM2) ANAPC4 PF12896.7 EAQ91218.1 - 1.5e-69 233.6 0.0 2.1e-69 233.1 0.0 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 VASt PF16016.5 EAQ91219.1 - 9.8e-36 123.5 0.8 1.8e-35 122.6 0.8 1.5 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain BAR_3 PF16746.5 EAQ91219.1 - 1.3e-11 44.7 0.0 3.1e-11 43.5 0.0 1.6 1 1 0 1 1 1 1 BAR domain of APPL family PH PF00169.29 EAQ91219.1 - 5.4e-05 23.7 0.0 0.00017 22.1 0.0 1.9 1 0 0 1 1 1 1 PH domain GRAM PF02893.20 EAQ91219.1 - 0.024 14.5 0.0 0.051 13.5 0.0 1.5 1 0 0 1 1 1 0 GRAM domain Myosin_TH1 PF06017.13 EAQ91219.1 - 0.058 13.1 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 Unconventional myosin tail, actin- and lipid-binding Adenylsucc_synt PF00709.21 EAQ91221.1 - 6.2e-163 542.6 0.0 7e-163 542.4 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase PhageP22-tail PF09251.10 EAQ91221.1 - 0.097 11.0 0.1 0.2 9.9 0.0 1.5 2 0 0 2 2 2 0 Salmonella phage P22 tail-spike ELO PF01151.18 EAQ91222.1 - 3e-82 275.9 10.9 3.6e-82 275.6 10.9 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family MlaE PF02405.16 EAQ91222.1 - 0.0091 15.7 8.2 0.02 14.6 8.2 1.5 1 0 0 1 1 1 1 Permease MlaE Synaptobrevin PF00957.21 EAQ91224.1 - 7.9e-15 54.4 0.5 1.2e-14 53.8 0.5 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 EAQ91224.1 - 7e-10 38.8 0.0 1.6e-09 37.7 0.0 1.6 1 1 0 1 1 1 1 Regulated-SNARE-like domain Herpes_teg_N PF04843.12 EAQ91224.1 - 0.074 12.7 0.1 0.2 11.3 0.0 1.7 2 0 0 2 2 2 0 Herpesvirus tegument protein, N-terminal conserved region MoaC PF01967.21 EAQ91225.1 - 5.9e-52 175.4 0.4 1.1e-51 174.5 0.4 1.4 1 0 0 1 1 1 1 MoaC family Radical_SAM PF04055.21 EAQ91225.1 - 2.5e-25 89.8 0.0 3.8e-25 89.2 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Mob_synth_C PF06463.13 EAQ91225.1 - 5.4e-22 78.1 0.3 5.5e-14 52.2 0.1 2.7 2 1 1 3 3 3 2 Molybdenum Cofactor Synthesis C Fer4_12 PF13353.6 EAQ91225.1 - 1e-05 25.8 0.0 7.3e-05 23.1 0.0 2.2 3 0 0 3 3 3 1 4Fe-4S single cluster domain PD40 PF07676.12 EAQ91226.1 - 0.13 12.3 0.1 0.7 9.9 0.0 2.3 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat IKI3 PF04762.12 EAQ91226.1 - 0.28 9.1 0.0 22 2.8 0.0 2.6 1 1 1 3 3 3 0 IKI3 family WD40 PF00400.32 EAQ91226.1 - 0.32 11.9 9.0 9.7 7.3 0.1 4.8 4 1 0 4 4 4 0 WD domain, G-beta repeat RRM_1 PF00076.22 EAQ91227.1 - 1.3e-09 37.7 0.0 5.6e-06 26.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Med3 PF11593.8 EAQ91227.1 - 0.94 8.6 17.8 1.9 7.6 17.8 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal FAM75 PF14650.6 EAQ91227.1 - 3.6 7.0 18.0 6.1 6.3 18.0 1.3 1 0 0 1 1 1 0 FAM75 family DUF3074 PF11274.8 EAQ91228.1 - 1.1e-56 191.8 0.0 1.1e-56 191.8 0.0 2.0 3 0 0 3 3 3 1 Protein of unknown function (DUF3074) START PF01852.19 EAQ91228.1 - 0.0013 18.2 0.1 0.005 16.3 0.1 1.9 2 0 0 2 2 2 1 START domain FlaC_arch PF05377.11 EAQ91228.1 - 0.15 12.5 2.0 0.33 11.4 0.1 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) TFIIA PF03153.13 EAQ91228.1 - 3.9 7.4 25.6 0.25 11.3 19.9 1.9 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Exonuc_VII_L PF02601.15 EAQ91228.1 - 8.8 5.8 18.8 14 5.1 18.8 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF3535 PF12054.8 EAQ91229.1 - 1.5e-116 390.2 0.4 4.9e-106 355.6 0.0 3.3 3 1 1 4 4 4 2 Domain of unknown function (DUF3535) SNF2_N PF00176.23 EAQ91229.1 - 2e-47 161.6 0.2 3.3e-45 154.3 0.2 2.2 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EAQ91229.1 - 6.7e-19 68.3 0.0 1.7e-18 66.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT PF02985.22 EAQ91229.1 - 1.4e-12 46.7 9.7 0.0095 16.1 0.0 8.5 9 0 0 9 9 9 4 HEAT repeat HEAT_2 PF13646.6 EAQ91229.1 - 1.8e-08 34.6 5.0 0.00021 21.6 0.1 6.1 6 0 0 6 6 6 1 HEAT repeats Vac14_Fab1_bd PF12755.7 EAQ91229.1 - 2e-06 28.3 0.9 0.25 12.0 0.0 4.1 2 1 1 3 3 3 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 EAQ91229.1 - 0.00013 22.3 4.6 8 7.1 0.0 7.3 8 0 0 8 8 8 2 HEAT-like repeat CLASP_N PF12348.8 EAQ91229.1 - 0.0099 15.5 0.6 2.2 7.8 0.5 3.4 3 1 0 3 3 3 1 CLASP N terminal ERCC3_RAD25_C PF16203.5 EAQ91229.1 - 0.16 11.2 0.0 0.29 10.3 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase SMC_N PF02463.19 EAQ91230.1 - 8.2e-58 195.4 25.4 1.4e-57 194.6 25.4 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 EAQ91230.1 - 1.3e-25 90.0 0.0 3.9e-25 88.4 0.0 1.9 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 EAQ91230.1 - 1.4e-14 54.7 13.8 4.1e-07 30.1 2.1 3.3 2 2 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EAQ91230.1 - 2.6e-14 54.2 26.7 2.6e-14 54.2 26.7 7.7 2 2 2 4 4 1 1 AAA domain AAA_15 PF13175.6 EAQ91230.1 - 3e-13 50.2 55.3 5.9e-11 42.7 12.1 3.9 2 2 1 3 3 3 2 AAA ATPase domain SbcCD_C PF13558.6 EAQ91230.1 - 0.00093 19.4 0.1 0.0047 17.1 0.1 2.3 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 EAQ91230.1 - 0.0025 17.5 0.0 0.0065 16.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain BRE1 PF08647.11 EAQ91230.1 - 0.005 16.9 6.3 0.005 16.9 6.3 8.3 4 2 2 8 8 8 2 BRE1 E3 ubiquitin ligase HsbA PF12296.8 EAQ91230.1 - 0.034 14.6 2.7 4.6 7.7 0.0 4.9 5 0 0 5 5 5 0 Hydrophobic surface binding protein A ABC_tran PF00005.27 EAQ91230.1 - 0.37 11.3 0.0 0.37 11.3 0.0 7.1 3 2 1 4 4 2 0 ABC transporter CCP_MauG PF03150.14 EAQ91230.1 - 1.3 9.7 0.0 1.3 9.7 0.0 3.9 2 1 0 3 3 3 0 Di-haem cytochrome c peroxidase DEAD PF00270.29 EAQ91230.1 - 5.9 6.6 10.3 1.4 8.7 0.0 4.1 4 2 0 4 4 4 0 DEAD/DEAH box helicase CDC37_N PF03234.14 EAQ91231.1 - 4.3e-50 169.9 1.5 4.3e-50 169.9 1.5 3.4 3 1 1 4 4 4 1 Cdc37 N terminal kinase binding CDC37_M PF08565.11 EAQ91231.1 - 2.4e-39 133.9 0.4 1.2e-38 131.7 0.2 2.1 2 0 0 2 2 2 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.10 EAQ91231.1 - 9.8e-30 102.6 3.0 9.8e-30 102.6 3.0 2.6 2 0 0 2 2 2 1 Cdc37 C terminal domain KdpC PF02669.15 EAQ91231.1 - 0.12 12.2 0.1 0.29 11.0 0.1 1.7 1 0 0 1 1 1 0 K+-transporting ATPase, c chain RVT_1 PF00078.27 EAQ91232.1 - 4.2e-19 68.9 0.0 6.9e-19 68.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HNH_repeat PF18780.1 EAQ91233.1 - 0.32 10.8 1.1 5.9 6.8 0.0 2.8 2 0 0 2 2 2 0 Homing endonuclease repeat Glyco_hydro_43 PF04616.14 EAQ91235.1 - 1.6e-44 152.4 9.7 2.1e-44 152.0 9.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 CBM_6 PF03422.15 EAQ91235.1 - 2.7e-31 108.5 2.9 7.5e-31 107.0 2.9 1.8 1 0 0 1 1 1 1 Carbohydrate binding module (family 6) DUF5010_C PF18099.1 EAQ91235.1 - 2.9e-12 46.7 0.3 6.1e-12 45.7 0.3 1.6 1 0 0 1 1 1 1 DUF5010 C-terminal domain Glyco_hydro_32N PF00251.20 EAQ91235.1 - 0.012 15.1 5.8 0.039 13.5 5.8 1.8 1 1 0 1 1 1 0 Glycosyl hydrolases family 32 N-terminal domain DUF155 PF02582.14 EAQ91237.1 - 7.7e-53 179.2 0.1 1.1e-52 178.7 0.1 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 HTH_29 PF13551.6 EAQ91237.1 - 0.099 12.7 0.0 0.23 11.5 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn helix HMG_box PF00505.19 EAQ91238.1 - 1.4e-08 35.0 1.7 1.9e-08 34.6 0.6 1.9 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EAQ91238.1 - 1.7e-08 34.9 1.5 1.7e-08 34.9 1.5 2.6 3 0 0 3 3 3 1 HMG-box domain Cpn60_TCP1 PF00118.24 EAQ91239.1 - 1.4e-152 508.8 11.2 1.6e-152 508.6 11.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PP1_inhibitor PF05361.12 EAQ91239.1 - 0.00034 20.6 0.8 0.0011 19.0 0.8 1.8 1 1 0 1 1 1 1 PKC-activated protein phosphatase-1 inhibitor EAL PF00563.20 EAQ91239.1 - 0.028 13.9 0.0 0.072 12.6 0.0 1.6 1 0 0 1 1 1 0 EAL domain PrpR_N PF06506.11 EAQ91239.1 - 0.045 13.3 0.7 0.17 11.4 0.1 2.3 3 0 0 3 3 3 0 Propionate catabolism activator tRNA-synt_1d PF00750.19 EAQ91239.1 - 0.072 12.0 1.0 0.22 10.4 0.3 2.1 1 1 2 3 3 3 0 tRNA synthetases class I (R) AAA_10 PF12846.7 EAQ91239.1 - 0.5 9.2 4.6 1.8 7.4 1.1 2.3 1 1 1 2 2 2 0 AAA-like domain PH_10 PF15411.6 EAQ91241.1 - 1.6e-29 102.7 0.4 2.5e-29 102.0 0.4 1.3 1 0 0 1 1 1 1 Pleckstrin homology domain VWA PF00092.28 EAQ91241.1 - 7.6e-14 52.3 0.0 1.2e-13 51.7 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 EAQ91241.1 - 1.1e-09 38.4 0.3 7e-09 35.8 0.3 2.2 1 1 0 1 1 1 1 von Willebrand factor type A domain DUF1147 PF06615.11 EAQ91241.1 - 0.18 11.9 0.5 0.45 10.6 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1147) PH PF00169.29 EAQ91241.1 - 0.18 12.3 0.1 0.39 11.2 0.1 1.5 1 0 0 1 1 1 0 PH domain Collagen PF01391.18 EAQ91241.1 - 6.5 6.6 37.3 0.56 10.0 31.3 2.2 2 0 0 2 2 2 0 Collagen triple helix repeat (20 copies) MFS_1 PF07690.16 EAQ91242.1 - 6.3e-23 81.3 34.7 2e-22 79.6 34.2 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily Wzy_C PF04932.15 EAQ91242.1 - 3.1 7.4 0.0 3.1 7.4 0.0 4.4 3 1 0 4 4 4 0 O-Antigen ligase Sacchrp_dh_NADP PF03435.18 EAQ91243.1 - 3.9e-15 56.3 0.1 6.2e-15 55.6 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 EAQ91243.1 - 0.014 15.9 0.0 0.021 15.3 0.0 1.3 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Ribosomal_L37ae PF01780.19 EAQ91244.1 - 7.3e-40 134.9 8.5 8.2e-40 134.8 8.5 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family zf-RING_13 PF17977.1 EAQ91244.1 - 0.00018 21.6 1.6 0.00026 21.0 1.6 1.2 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Zn_Tnp_IS1595 PF12760.7 EAQ91244.1 - 0.0027 17.7 3.1 0.0045 16.9 3.1 1.4 1 0 0 1 1 1 1 Transposase zinc-ribbon domain zf-H2C2_2 PF13465.6 EAQ91244.1 - 0.011 16.1 1.4 0.63 10.6 0.2 2.3 2 0 0 2 2 2 0 Zinc-finger double domain Zn_ribbon_SprT PF17283.2 EAQ91244.1 - 0.022 14.7 2.5 0.04 13.8 2.5 1.4 1 0 0 1 1 1 0 SprT-like zinc ribbon domain DUF1451 PF07295.11 EAQ91244.1 - 0.027 14.5 0.5 0.038 14.0 0.5 1.2 1 0 0 1 1 1 0 Zinc-ribbon containing domain Elf1 PF05129.13 EAQ91244.1 - 0.092 12.8 2.9 0.16 12.0 2.9 1.5 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like zf-BED PF02892.15 EAQ91244.1 - 0.11 12.5 5.3 0.46 10.5 0.4 2.2 1 1 1 2 2 2 0 BED zinc finger NCD3G PF07562.14 EAQ91244.1 - 0.24 11.4 3.4 0.47 10.5 3.4 1.4 1 1 0 1 1 1 0 Nine Cysteines Domain of family 3 GPCR C1_2 PF03107.16 EAQ91244.1 - 0.38 11.1 3.3 5.5 7.4 3.4 2.0 1 1 1 2 2 2 0 C1 domain PHD PF00628.29 EAQ91245.1 - 7.8e-10 38.5 6.4 7.8e-10 38.5 6.4 2.9 2 1 0 2 2 2 1 PHD-finger zf-rbx1 PF12678.7 EAQ91245.1 - 4.2e-08 33.4 10.1 2.1e-06 27.9 1.9 3.2 3 0 0 3 3 3 2 RING-H2 zinc finger domain zf-RING_2 PF13639.6 EAQ91245.1 - 7.1e-08 32.7 19.9 8.5e-07 29.2 2.9 3.6 3 1 0 3 3 3 1 Ring finger domain Prok-RING_4 PF14447.6 EAQ91245.1 - 3.5e-06 26.8 2.1 3.5e-06 26.8 2.1 2.7 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 EAQ91245.1 - 1.3e-05 25.2 8.3 0.0012 18.9 1.1 2.4 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 EAQ91245.1 - 0.00024 20.8 2.2 0.00024 20.8 2.2 3.6 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EAQ91245.1 - 0.00071 19.5 2.4 0.00071 19.5 2.4 3.1 4 0 0 4 4 4 1 zinc-RING finger domain PHD_2 PF13831.6 EAQ91245.1 - 0.0011 18.5 1.2 0.0011 18.5 1.2 2.1 2 0 0 2 2 2 1 PHD-finger Zn_ribbon_17 PF17120.5 EAQ91245.1 - 0.0013 18.3 12.7 0.0022 17.6 3.6 3.1 3 0 0 3 3 3 1 Zinc-ribbon, C4HC2 type zf-C3HC4 PF00097.25 EAQ91245.1 - 0.0015 18.3 4.2 0.0015 18.3 4.2 3.4 2 2 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EAQ91245.1 - 0.0016 18.2 2.0 0.0016 18.2 2.0 3.7 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-PHD-like PF15446.6 EAQ91245.1 - 0.03 14.0 0.9 0.03 14.0 0.9 2.2 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain Rad50_zn_hook PF04423.14 EAQ91245.1 - 0.17 11.7 0.8 9.1 6.2 0.0 2.7 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-RING_9 PF13901.6 EAQ91245.1 - 0.33 10.9 11.7 1.6 8.6 1.6 2.3 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon Prok-RING_1 PF14446.6 EAQ91245.1 - 0.6 10.1 15.7 0.032 14.1 2.6 3.3 3 1 1 4 4 4 0 Prokaryotic RING finger family 1 DZR PF12773.7 EAQ91245.1 - 2.6 8.2 8.4 2.7 8.1 1.4 3.0 2 1 1 3 3 2 0 Double zinc ribbon zf-RING_4 PF14570.6 EAQ91245.1 - 3.5 7.5 6.3 1 9.2 1.0 2.5 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain C1_2 PF03107.16 EAQ91245.1 - 3.7 8.0 7.8 0.44 10.9 0.6 2.7 2 1 0 2 2 2 0 C1 domain Zf_RING PF16744.5 EAQ91245.1 - 5.6 7.2 15.2 3.7 7.7 0.7 3.9 3 1 1 4 4 4 0 KIAA1045 RING finger MRP-L46 PF11788.8 EAQ91246.1 - 6.5e-35 120.4 0.1 1.5e-34 119.3 0.1 1.6 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 2OG-FeII_Oxy_4 PF13661.6 EAQ91246.1 - 0.0035 18.0 0.0 0.0062 17.2 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CAF1 PF04857.20 EAQ91247.1 - 1.4e-41 142.7 0.0 1.8e-41 142.4 0.0 1.0 1 0 0 1 1 1 1 CAF1 family ribonuclease DUF3716 PF12511.8 EAQ91248.1 - 0.016 15.2 2.1 0.034 14.2 2.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3716) tRNA_bind_2 PF13725.6 EAQ91249.1 - 9.5 5.8 7.1 15 5.2 7.1 1.2 1 0 0 1 1 1 0 Possible tRNA binding domain DUF2076 PF09849.9 EAQ91252.1 - 0.073 13.1 0.2 0.073 13.1 0.2 3.3 2 1 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2076) SbcCD_C PF13558.6 EAQ91252.1 - 0.72 10.1 0.0 0.72 10.1 0.0 3.0 4 0 0 4 4 4 0 Putative exonuclease SbcCD, C subunit Nnf1 PF03980.14 EAQ91253.1 - 5.1e-34 117.0 0.2 5.1e-34 117.0 0.2 1.9 2 0 0 2 2 2 1 Nnf1 SHE3 PF17078.5 EAQ91253.1 - 0.12 12.1 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 APG6_N PF17675.1 EAQ91253.1 - 0.44 11.1 4.2 0.53 10.8 3.2 1.5 1 1 0 1 1 1 0 Apg6 coiled-coil region PH_9 PF15410.6 EAQ91254.1 - 2.8e-06 27.7 0.0 4.3e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Pleckstrin homology domain DUF1098 PF06497.11 EAQ91254.1 - 0.042 14.3 0.2 0.068 13.6 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1098) NTF2 PF02136.20 EAQ91255.1 - 1.4e-22 80.5 0.2 2.1e-22 79.9 0.2 1.3 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.22 EAQ91255.1 - 7.3e-08 32.1 0.1 1.4e-07 31.2 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 EAQ91255.1 - 0.017 15.2 0.0 0.041 13.9 0.0 1.7 1 0 0 1 1 1 0 RNA binding motif Fungal_trans_2 PF11951.8 EAQ91256.1 - 2.3e-05 23.4 0.0 0.00022 20.2 0.0 2.2 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-NOSIP PF15906.5 EAQ91258.1 - 6.1e-08 32.7 0.0 9.4e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein zf-RING_UBOX PF13445.6 EAQ91258.1 - 0.016 15.2 0.5 0.03 14.3 0.5 1.4 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4 PF00097.25 EAQ91258.1 - 0.037 13.9 1.8 0.06 13.2 1.8 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) HA2 PF04408.23 EAQ91258.1 - 0.73 10.1 3.0 0.29 11.4 0.3 1.7 2 0 0 2 2 2 0 Helicase associated domain (HA2) Mito_carr PF00153.27 EAQ91259.1 - 4.2e-42 142.0 0.1 2.6e-12 46.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein MULE PF10551.9 EAQ91260.1 - 6.9e-19 68.1 0.0 1.4e-18 67.1 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain SCA7 PF08313.12 EAQ91261.1 - 3.4e-31 106.9 2.9 4e-31 106.7 0.1 2.4 2 0 0 2 2 2 1 SCA7, zinc-binding domain zf-BED PF02892.15 EAQ91261.1 - 0.14 12.2 0.1 0.29 11.2 0.1 1.5 1 0 0 1 1 1 0 BED zinc finger Pkinase PF00069.25 EAQ91262.1 - 1.3e-75 254.2 0.0 1.5e-75 253.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ91262.1 - 3.6e-37 128.1 0.0 4.7e-37 127.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EAQ91262.1 - 0.0017 17.4 0.0 0.025 13.5 0.0 2.1 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EAQ91262.1 - 0.038 13.9 0.0 0.11 12.4 0.0 1.6 1 1 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 EAQ91262.1 - 0.16 11.3 0.1 0.33 10.3 0.1 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Peptidase_M28 PF04389.17 EAQ91263.1 - 2.8e-35 121.8 0.0 4.5e-35 121.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Myosin-VI_CBD PF16521.5 EAQ91264.1 - 0.17 11.9 0.0 0.35 10.9 0.0 1.4 1 0 0 1 1 1 0 Myosin VI cargo binding domain Dynamin_N PF00350.23 EAQ91266.1 - 5.1e-18 65.7 0.0 1.2e-17 64.5 0.0 1.7 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 EAQ91266.1 - 2e-06 27.8 0.0 4.7e-05 23.4 0.0 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 EAQ91266.1 - 0.00028 21.4 0.0 0.0019 18.7 0.0 2.3 2 1 0 2 2 2 1 ABC transporter RsgA_GTPase PF03193.16 EAQ91266.1 - 0.0016 18.3 0.1 0.0045 16.9 0.0 1.8 2 0 0 2 2 2 1 RsgA GTPase DUF87 PF01935.17 EAQ91266.1 - 0.0079 16.3 1.0 0.0079 16.3 1.0 2.1 2 1 0 2 2 2 1 Helicase HerA, central domain AAA_16 PF13191.6 EAQ91266.1 - 0.0093 16.4 0.1 0.036 14.5 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 EAQ91266.1 - 0.01 15.3 0.0 0.018 14.5 0.0 1.4 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EAQ91266.1 - 0.012 15.9 0.0 0.15 12.4 0.0 2.5 2 1 0 2 2 2 0 AAA domain AIG1 PF04548.16 EAQ91266.1 - 0.014 14.7 0.0 0.034 13.5 0.0 1.7 1 0 0 1 1 1 0 AIG1 family NB-ARC PF00931.22 EAQ91266.1 - 0.047 12.9 0.0 0.15 11.2 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain Zeta_toxin PF06414.12 EAQ91266.1 - 0.054 12.8 0.0 0.13 11.5 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin TMF_TATA_bd PF12325.8 EAQ91266.1 - 0.09 13.0 1.5 0.16 12.2 0.1 2.2 2 0 0 2 2 1 0 TATA element modulatory factor 1 TATA binding PRK PF00485.18 EAQ91266.1 - 0.092 12.5 0.0 0.2 11.4 0.0 1.7 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family MeaB PF03308.16 EAQ91266.1 - 0.13 11.2 0.1 0.19 10.6 0.1 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_29 PF13555.6 EAQ91266.1 - 0.14 11.9 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain NUDIX_2 PF13869.6 EAQ91267.1 - 1.2e-80 269.6 0.0 1.4e-80 269.4 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase ABC_membrane PF00664.23 EAQ91268.1 - 2.4e-90 302.9 31.3 4e-50 171.0 3.9 2.7 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 EAQ91268.1 - 7.2e-27 94.6 1.4 4.9e-16 59.5 0.0 3.5 2 1 0 3 3 3 2 ABC transporter RsgA_GTPase PF03193.16 EAQ91268.1 - 2.9e-05 24.0 0.1 0.1 12.5 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EAQ91268.1 - 3.2e-05 24.0 0.4 0.24 11.5 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.6 EAQ91268.1 - 0.0045 17.5 0.2 0.94 9.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EAQ91268.1 - 0.0077 16.0 1.4 3 7.7 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.19 EAQ91268.1 - 0.016 14.6 0.7 1.4 8.3 0.1 2.7 2 1 1 3 3 3 0 RecF/RecN/SMC N terminal domain ABC_membrane_2 PF06472.15 EAQ91268.1 - 0.029 13.8 6.8 0.059 12.8 0.4 2.6 2 0 0 2 2 2 0 ABC transporter transmembrane region 2 AAA_16 PF13191.6 EAQ91268.1 - 0.046 14.1 0.0 4.1 7.8 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain Dynamin_N PF00350.23 EAQ91268.1 - 0.084 12.9 1.6 3.7 7.6 0.1 2.4 2 0 0 2 2 2 0 Dynamin family DUF87 PF01935.17 EAQ91268.1 - 0.1 12.7 1.3 0.96 9.5 0.1 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_21 PF13304.6 EAQ91268.1 - 0.14 11.9 2.1 8.4 6.1 0.3 2.4 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system T2SSE PF00437.20 EAQ91268.1 - 0.15 11.1 0.1 0.54 9.3 0.1 1.8 1 1 0 1 1 1 0 Type II/IV secretion system protein AAA_27 PF13514.6 EAQ91268.1 - 0.16 11.6 0.1 0.6 9.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain MWFE PF15879.5 EAQ91268.1 - 4.9 7.4 5.5 2 8.6 0.5 2.9 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase MWFE subunit DUF2841 PF11001.8 EAQ91270.1 - 1.8e-34 118.5 0.1 1.8e-34 118.5 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2841) Presenilin PF01080.17 EAQ91270.1 - 3.7 6.2 10.1 5.9 5.6 10.1 1.3 1 0 0 1 1 1 0 Presenilin DUF2431 PF10354.9 EAQ91271.1 - 9e-62 208.3 0.0 1.1e-61 207.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) SDA1 PF05285.12 EAQ91271.1 - 6.1 6.2 23.0 9.9 5.5 23.0 1.3 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 EAQ91271.1 - 8.1 4.5 22.3 13 3.9 22.3 1.2 1 0 0 1 1 1 0 Nop14-like family FUSC PF04632.12 EAQ91272.1 - 1.9 6.9 8.3 0.072 11.6 1.7 1.7 2 0 0 2 2 2 0 Fusaric acid resistance protein family ThiF PF00899.21 EAQ91273.1 - 4.6e-27 94.9 0.0 6.9e-27 94.4 0.0 1.2 1 0 0 1 1 1 1 ThiF family eIF-6 PF01912.18 EAQ91275.1 - 4.7e-79 264.4 0.7 4.7e-79 264.4 0.7 1.3 2 0 0 2 2 2 1 eIF-6 family GET2 PF08690.10 EAQ91276.1 - 0.0057 16.4 0.9 0.0057 16.4 0.9 2.0 2 1 0 2 2 2 1 GET complex subunit GET2 IFT20 PF14931.6 EAQ91276.1 - 0.083 13.1 0.4 2.1 8.6 2.2 2.2 2 0 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 ZapB PF06005.12 EAQ91276.1 - 0.42 11.1 6.2 11 6.6 3.1 2.9 2 1 1 3 3 3 0 Cell division protein ZapB Med9 PF07544.13 EAQ91276.1 - 0.56 10.3 2.2 3.5 7.8 0.3 2.3 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 FSA_C PF10479.9 EAQ91276.1 - 0.95 7.5 11.9 1.1 7.3 0.3 2.1 2 0 0 2 2 2 0 Fragile site-associated protein C-terminus Macoilin PF09726.9 EAQ91276.1 - 9.8 4.6 10.8 3.8 5.9 7.8 1.8 1 1 1 2 2 2 0 Macoilin family CAF1 PF04857.20 EAQ91277.1 - 2.3e-08 33.6 0.0 0.00016 21.0 0.0 2.1 2 0 0 2 2 2 2 CAF1 family ribonuclease RFX_DNA_binding PF02257.15 EAQ91277.1 - 0.22 12.2 0.0 0.44 11.2 0.0 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain CLTH PF10607.9 EAQ91278.1 - 4.4e-40 137.0 0.0 6.6e-40 136.4 0.0 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 EAQ91278.1 - 0.014 15.3 0.0 0.033 14.2 0.0 1.7 1 0 0 1 1 1 0 LisH HLH PF00010.26 EAQ91279.1 - 3.4e-10 39.7 0.0 7.6e-10 38.6 0.0 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DivIC PF04977.15 EAQ91279.1 - 0.18 11.6 1.1 0.39 10.5 1.1 1.6 1 0 0 1 1 1 0 Septum formation initiator Aminotran_3 PF00202.21 EAQ91280.1 - 4.6e-114 381.2 0.0 5.2e-114 381.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 EAQ91280.1 - 0.12 11.6 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II SET PF00856.28 EAQ91281.1 - 9.4e-19 68.4 3.1 1.9e-18 67.4 0.1 3.1 3 1 0 3 3 3 1 SET domain AWS PF17907.1 EAQ91281.1 - 7.6e-14 51.5 11.3 7.6e-14 51.5 11.3 3.0 3 0 0 3 3 3 1 AWS domain SRI PF08236.11 EAQ91281.1 - 6e-13 48.8 5.4 1.5e-12 47.5 5.4 1.7 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain WW PF00397.26 EAQ91281.1 - 1.6e-06 28.0 1.3 3.9e-06 26.8 1.3 1.7 1 0 0 1 1 1 1 WW domain Med26 PF08711.11 EAQ91281.1 - 0.00078 19.4 0.1 0.0027 17.7 0.1 1.9 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Terpene_synth PF01397.21 EAQ91281.1 - 0.033 13.9 0.0 0.072 12.8 0.0 1.5 1 0 0 1 1 1 0 Terpene synthase, N-terminal domain Peptidase_M16_C PF05193.21 EAQ91281.1 - 0.18 11.8 3.4 0.4 10.7 0.5 2.7 3 0 0 3 3 3 0 Peptidase M16 inactive domain AT_hook PF02178.19 EAQ91282.1 - 0.041 13.8 2.0 0.041 13.8 2.0 2.7 2 0 0 2 2 2 0 AT hook motif XPC-binding PF09280.11 EAQ91284.1 - 4.4e-24 84.0 12.9 7.6e-24 83.2 12.9 1.4 1 0 0 1 1 1 1 XPC-binding domain UBA PF00627.31 EAQ91284.1 - 9.6e-20 70.1 7.6 7.7e-12 44.9 0.4 2.6 2 0 0 2 2 2 2 UBA/TS-N domain ubiquitin PF00240.23 EAQ91284.1 - 1.9e-19 69.2 0.4 3.4e-19 68.3 0.4 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EAQ91284.1 - 3e-07 30.2 0.6 5.2e-07 29.4 0.6 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like WIYLD PF10440.9 EAQ91284.1 - 0.032 14.0 0.8 2.3 8.1 0.3 2.3 2 0 0 2 2 2 0 Ubiquitin-binding WIYLD domain UBA_3 PF09288.10 EAQ91284.1 - 0.034 14.0 0.0 3.7 7.4 0.0 2.4 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain Rad60-SLD_2 PF13881.6 EAQ91284.1 - 0.092 12.9 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like MCM_N PF14551.6 EAQ91284.1 - 0.11 13.1 0.1 0.25 12.0 0.1 1.5 1 0 0 1 1 1 0 MCM N-terminal domain DUF2407 PF10302.9 EAQ91284.1 - 0.14 12.8 0.0 0.28 11.8 0.0 1.5 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain DUF3391 PF11871.8 EAQ91284.1 - 0.71 10.4 6.5 39 4.8 6.5 2.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3391) Myb_DNA-bind_7 PF15963.5 EAQ91285.1 - 1.6e-27 95.2 1.0 4.5e-27 93.8 1.0 1.8 1 0 0 1 1 1 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 EAQ91285.1 - 2.2e-08 34.1 0.0 4.1e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAQ91285.1 - 0.0092 16.2 0.0 0.019 15.2 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain BRE1 PF08647.11 EAQ91286.1 - 7.2e-28 96.5 7.1 7.2e-28 96.5 7.1 7.1 4 2 3 7 7 7 3 BRE1 E3 ubiquitin ligase Snapin_Pallidin PF14712.6 EAQ91286.1 - 0.0038 17.6 4.6 0.0038 17.6 4.6 6.3 5 2 3 8 8 8 1 Snapin/Pallidin JIP_LZII PF16471.5 EAQ91286.1 - 0.006 16.7 2.1 0.006 16.7 2.1 7.6 6 2 1 8 8 8 2 JNK-interacting protein leucine zipper II DUF5113 PF17140.4 EAQ91286.1 - 0.32 10.8 3.2 0.51 10.1 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5113) Baculo_PEP_C PF04513.12 EAQ91286.1 - 6.3 6.8 27.4 0.18 11.8 3.6 5.3 4 1 3 7 7 7 0 Baculovirus polyhedron envelope protein, PEP, C terminus Totivirus_coat PF05518.11 EAQ91287.1 - 1.2 7.1 10.2 1.5 6.8 10.2 1.0 1 0 0 1 1 1 0 Totivirus coat protein ABC_membrane PF00664.23 EAQ91288.1 - 5.5e-82 275.5 36.5 1.1e-51 176.1 18.2 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EAQ91288.1 - 9.6e-51 171.9 0.0 1.2e-29 103.5 0.0 2.9 2 1 0 2 2 2 2 ABC transporter AAA_16 PF13191.6 EAQ91288.1 - 3.9e-07 30.6 0.1 0.0076 16.6 0.0 2.9 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 EAQ91288.1 - 8.6e-07 28.6 3.9 0.0014 18.3 0.4 3.3 3 0 0 3 3 3 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EAQ91288.1 - 1.3e-05 25.1 0.2 0.13 12.1 0.0 2.8 3 0 0 3 3 2 2 RsgA GTPase AAA_21 PF13304.6 EAQ91288.1 - 3.4e-05 23.8 0.0 0.78 9.5 0.0 3.2 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 EAQ91288.1 - 3.4e-05 23.5 0.1 0.19 11.2 0.1 3.3 3 0 0 3 3 3 2 AAA domain AAA_15 PF13175.6 EAQ91288.1 - 4.7e-05 23.3 0.0 0.14 11.9 0.0 2.5 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 EAQ91288.1 - 0.00067 19.9 0.0 0.55 10.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EAQ91288.1 - 0.00082 19.1 0.3 1.9 8.2 0.1 2.7 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 EAQ91288.1 - 0.0043 16.6 0.1 2.1 7.8 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_28 PF13521.6 EAQ91288.1 - 0.0051 17.1 0.5 0.58 10.4 0.1 2.6 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 EAQ91288.1 - 0.0066 15.8 0.0 4.3 6.6 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin G-alpha PF00503.20 EAQ91288.1 - 0.0077 15.4 0.0 2.8 7.0 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit AAA_33 PF13671.6 EAQ91288.1 - 0.014 15.6 0.0 7.5 6.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EAQ91288.1 - 0.02 15.5 0.0 13 6.3 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 EAQ91288.1 - 0.032 14.2 0.2 12 5.8 0.0 3.1 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 EAQ91288.1 - 0.075 12.8 0.0 8.5 6.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.25 EAQ91288.1 - 0.078 12.6 0.1 12 5.5 0.0 3.1 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain Mg_chelatase PF01078.21 EAQ91288.1 - 0.092 12.1 0.0 8.2 5.7 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA PF00004.29 EAQ91288.1 - 0.098 13.1 0.6 24 5.4 0.2 3.6 2 2 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 EAQ91288.1 - 0.12 11.5 0.0 12 4.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) ABC_ATPase PF09818.9 EAQ91288.1 - 0.12 11.1 3.3 0.16 10.7 0.0 2.6 3 0 0 3 3 3 0 Predicted ATPase of the ABC class MMR_HSR1 PF01926.23 EAQ91288.1 - 0.18 11.9 2.4 18 5.4 0.0 3.3 3 0 0 3 3 3 0 50S ribosome-binding GTPase DUF2852 PF11014.8 EAQ91288.1 - 0.26 11.5 1.5 2.7 8.2 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2852) DUF87 PF01935.17 EAQ91288.1 - 0.36 10.9 4.7 5.3 7.1 0.0 3.0 3 0 0 3 3 3 0 Helicase HerA, central domain SMC_N PF02463.19 EAQ91288.1 - 0.48 9.8 3.2 8.3 5.8 0.2 3.3 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EAQ91288.1 - 4.9 7.6 8.3 6.6 7.2 1.2 3.0 3 0 0 3 3 3 0 AAA domain RL10P_insert PF17777.1 EAQ91289.1 - 1.7e-21 76.0 0.0 2.8e-21 75.3 0.0 1.4 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 EAQ91289.1 - 1.8e-08 34.4 0.0 3.5e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L10 U1snRNP70_N PF12220.8 EAQ91290.1 - 8e-27 93.7 2.7 1.7e-26 92.7 2.7 1.5 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.22 EAQ91290.1 - 2.7e-16 59.1 0.1 1.1e-15 57.2 0.1 1.9 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EAQ91290.1 - 0.00018 21.6 0.0 0.00032 20.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif L51_S25_CI-B8 PF05047.16 EAQ91291.1 - 8.1e-15 54.5 0.0 1.2e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain TIM PF00121.18 EAQ91292.1 - 1.1e-92 309.8 1.1 1.3e-92 309.6 1.1 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase U3_snoRNA_assoc PF08297.11 EAQ91293.1 - 1.6e-15 57.6 3.3 1.6e-15 57.6 3.3 3.7 3 2 0 3 3 3 1 U3 snoRNA associated DUF3959 PF13105.6 EAQ91293.1 - 0.49 9.9 1.3 0.57 9.6 0.4 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3959) Med3 PF11593.8 EAQ91294.1 - 0.036 13.3 2.4 0.058 12.6 2.4 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal TPR_1 PF00515.28 EAQ91294.1 - 0.074 12.9 0.1 0.72 9.8 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 EAQ91294.1 - 0.085 13.0 0.1 0.6 10.4 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Ank_2 PF12796.7 EAQ91294.1 - 0.12 13.0 0.1 0.27 11.8 0.1 1.5 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Spt20 PF12090.8 EAQ91294.1 - 3.7 7.1 9.3 6.1 6.4 9.3 1.3 1 0 0 1 1 1 0 Spt20 family DUF1180 PF06679.12 EAQ91296.1 - 0.42 11.0 3.5 1.1 9.6 3.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Cullin PF00888.22 EAQ91297.1 - 2.1e-149 499.0 0.0 8.9e-147 490.3 0.0 2.1 2 0 0 2 2 2 2 Cullin family Cullin_Nedd8 PF10557.9 EAQ91297.1 - 2.3e-26 91.6 0.2 5.1e-26 90.5 0.2 1.6 1 0 0 1 1 1 1 Cullin protein neddylation domain PQ-loop PF04193.14 EAQ91298.1 - 3.3e-41 138.9 8.9 2.6e-21 75.1 1.8 2.7 2 0 0 2 2 2 2 PQ loop repeat ECH_1 PF00378.20 EAQ91299.1 - 7.5e-22 77.8 0.1 4.6e-21 75.3 0.1 1.9 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EAQ91299.1 - 3.9e-11 43.0 0.0 5.2e-11 42.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase TPR_10 PF13374.6 EAQ91300.1 - 3.8e-77 252.3 1.5 3.7e-14 52.1 0.0 6.6 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_12 PF13424.6 EAQ91300.1 - 8.7e-60 199.0 5.9 7e-16 58.3 0.0 6.3 1 1 5 6 6 6 6 Tetratricopeptide repeat TPR_7 PF13176.6 EAQ91300.1 - 2.6e-25 86.5 3.3 1.2e-05 25.0 0.0 6.4 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 EAQ91300.1 - 7.7e-18 63.1 0.2 0.0071 16.4 0.0 6.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 EAQ91300.1 - 6.2e-15 55.6 0.0 0.0054 17.4 0.0 6.0 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_1 PF00515.28 EAQ91300.1 - 3.2e-14 52.1 0.0 0.016 15.0 0.0 5.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 EAQ91300.1 - 1.8e-12 46.7 1.4 0.077 13.4 0.0 5.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_4 PF07721.14 EAQ91300.1 - 3.6e-11 42.6 0.1 6 7.8 0.0 6.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_MalT PF17874.1 EAQ91300.1 - 8.7e-11 41.8 8.9 6.8e-09 35.5 2.0 2.2 1 1 1 2 2 2 2 MalT-like TPR region TPR_19 PF14559.6 EAQ91300.1 - 1.3e-10 41.6 1.3 0.026 15.0 0.0 5.2 1 1 2 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 EAQ91300.1 - 1.3e-09 37.5 0.3 0.35 11.2 0.0 5.6 6 0 0 6 6 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 EAQ91300.1 - 6.5e-08 32.8 4.1 7.4 7.7 0.0 6.9 6 1 1 7 7 7 0 Tetratricopeptide repeat NB-ARC PF00931.22 EAQ91300.1 - 1e-07 31.4 0.0 4.1e-07 29.4 0.0 1.9 2 0 0 2 2 2 1 NB-ARC domain TPR_5 PF12688.7 EAQ91300.1 - 7.9e-07 29.3 0.0 0.58 10.4 0.0 3.7 1 1 2 3 3 3 2 Tetratrico peptide repeat PPR PF01535.20 EAQ91300.1 - 2.2e-06 27.5 1.3 1.3 9.5 0.0 4.9 5 0 0 5 5 4 1 PPR repeat ANAPC3 PF12895.7 EAQ91300.1 - 9.7e-05 22.5 0.3 1.9 8.8 0.0 5.0 3 1 2 5 5 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 EAQ91300.1 - 0.00014 22.3 2.3 12 6.8 0.0 5.2 5 0 0 5 5 4 0 Tetratricopeptide repeat Ses_B PF17046.5 EAQ91300.1 - 0.00029 20.7 1.0 0.00068 19.5 1.0 1.7 1 0 0 1 1 1 1 SesB domain on fungal death-pathway protein NACHT PF05729.12 EAQ91300.1 - 0.00081 19.3 0.0 0.0015 18.5 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_25 PF13481.6 EAQ91300.1 - 0.003 17.2 0.0 0.0055 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain SnoaL_4 PF13577.6 EAQ91300.1 - 0.0039 17.3 0.9 17 5.6 0.0 3.7 1 1 1 3 3 3 0 SnoaL-like domain RPN6_N PF18055.1 EAQ91300.1 - 0.0059 17.0 0.6 4.3 7.7 0.1 3.0 1 1 3 4 4 4 2 26S proteasome regulatory subunit RPN6 N-terminal domain Ntox35 PF15534.6 EAQ91300.1 - 0.0071 16.8 2.4 29 5.2 0.0 4.1 2 2 2 4 4 4 0 Bacterial toxin 35 TPR_20 PF14561.6 EAQ91300.1 - 0.0083 16.4 0.4 25 5.3 0.0 4.5 1 1 4 5 5 5 0 Tetratricopeptide repeat HemY_N PF07219.13 EAQ91300.1 - 0.025 14.7 4.9 53 4.1 0.1 4.9 2 1 3 5 5 5 0 HemY protein N-terminus PPR_2 PF13041.6 EAQ91300.1 - 0.042 14.1 1.6 28 5.0 0.0 4.1 4 0 0 4 4 4 0 PPR repeat family PPR_1 PF12854.7 EAQ91300.1 - 0.11 12.2 1.0 75 3.2 0.0 4.1 4 0 0 4 4 4 0 PPR repeat DUF1897 PF09005.10 EAQ91300.1 - 0.11 12.0 0.1 75 2.9 0.0 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF1897) NDC10_II PF16787.5 EAQ91301.1 - 6.5e-62 209.4 0.0 1.4e-61 208.3 0.0 1.5 2 0 0 2 2 2 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 DDE_1 PF03184.19 EAQ91301.1 - 1.4e-26 93.2 0.0 2.5e-26 92.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease GCR1_C PF12550.8 EAQ91301.1 - 1.3e-20 73.5 0.5 1.3e-20 73.5 0.5 2.0 2 0 0 2 2 2 1 Transcriptional activator of glycolytic enzymes HTH_psq PF05225.16 EAQ91301.1 - 3.2e-10 39.6 0.0 7e-10 38.5 0.0 1.6 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.16 EAQ91301.1 - 1.3e-07 31.5 0.1 7.3e-07 29.1 0.0 2.3 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain zf-Dof PF02701.15 EAQ91301.1 - 0.041 14.0 0.1 0.11 12.7 0.1 1.6 1 0 0 1 1 1 0 Dof domain, zinc finger SpoIIID PF12116.8 EAQ91301.1 - 0.073 13.2 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Stage III sporulation protein D HTH_23 PF13384.6 EAQ91301.1 - 0.099 12.5 0.4 0.91 9.4 0.0 2.9 2 0 0 2 2 2 0 Homeodomain-like domain MULE PF10551.9 EAQ91302.1 - 1.6e-25 89.3 0.1 4e-25 88.1 0.1 1.7 1 0 0 1 1 1 1 MULE transposase domain NUDIX-like PF09296.11 EAQ91302.1 - 3.2e-20 72.7 0.1 1.1e-19 71.0 0.0 2.0 2 0 0 2 2 2 1 NADH pyrophosphatase-like rudimentary NUDIX domain NUDIX PF00293.28 EAQ91302.1 - 2e-14 53.8 0.1 6.4e-14 52.1 0.1 1.8 1 0 0 1 1 1 1 NUDIX domain zf-NADH-PPase PF09297.11 EAQ91302.1 - 3.8e-09 36.0 2.2 9.1e-09 34.8 2.2 1.6 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain FAR1 PF03101.15 EAQ91302.1 - 0.013 16.1 0.1 0.027 15.2 0.1 1.5 1 0 0 1 1 1 0 FAR1 DNA-binding domain Ribosomal_L1 PF00687.21 EAQ91303.1 - 2.5e-32 112.3 0.4 2.8e-32 112.1 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Ndr PF03096.14 EAQ91303.1 - 0.11 11.2 0.0 0.17 10.5 0.0 1.3 1 0 0 1 1 1 0 Ndr family Zn_clus PF00172.18 EAQ91305.1 - 3.6e-06 27.0 8.0 7e-06 26.1 8.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.26 EAQ91309.1 - 0.0017 18.7 4.8 0.14 12.7 0.2 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EAQ91309.1 - 0.26 12.2 7.9 3.1 8.9 0.9 3.2 2 1 0 2 2 2 0 C2H2-type zinc finger Ndc1_Nup PF09531.10 EAQ91309.1 - 9.3 4.8 10.2 1.3 7.6 2.3 2.0 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup Isochorismatase PF00857.20 EAQ91310.1 - 1.8e-10 41.3 0.0 2.5e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 Isochorismatase family Kinetochor_Ybp2 PF08568.10 EAQ91311.1 - 3.3e-96 323.2 0.2 4.6e-96 322.7 0.2 1.1 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin Glyco_transf_28 PF03033.20 EAQ91312.1 - 2.7e-13 50.1 0.2 4.6e-12 46.2 0.2 2.3 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 EAQ91312.1 - 2.8e-08 33.0 0.0 4.4e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 EAQ91312.1 - 0.0022 18.0 0.0 0.0043 17.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain ATG_C PF09333.11 EAQ91312.1 - 0.025 14.9 0.0 0.23 11.8 0.0 2.6 2 0 0 2 2 2 0 Autophagy-related protein C terminal domain YL1 PF05764.13 EAQ91312.1 - 0.32 11.1 25.3 0.055 13.6 6.3 2.6 2 0 0 2 2 2 0 YL1 nuclear protein UPF0767 PF15990.5 EAQ91312.1 - 0.94 9.7 4.5 0.49 10.6 0.2 2.4 2 0 0 2 2 2 0 UPF0767 family Peptidase_M66 PF10462.9 EAQ91313.1 - 3.8 6.4 7.3 5.9 5.7 7.3 1.2 1 0 0 1 1 1 0 Peptidase M66 COesterase PF00135.28 EAQ91314.1 - 6.3e-74 249.7 0.0 2.5e-73 247.7 0.0 1.7 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EAQ91314.1 - 3.6e-11 43.3 0.2 2.3e-10 40.7 0.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EAQ91314.1 - 0.016 14.7 0.3 0.028 13.9 0.3 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_9 PF10081.9 EAQ91314.1 - 0.13 11.3 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta-hydrolase family HeLo PF14479.6 EAQ91315.1 - 5.9e-34 117.7 5.9 1.2e-18 67.8 0.1 2.5 1 1 1 2 2 2 2 Prion-inhibition and propagation Pkinase_Tyr PF07714.17 EAQ91315.1 - 4e-05 23.0 0.3 0.00039 19.8 0.3 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EAQ91315.1 - 0.0017 17.7 0.0 0.0044 16.4 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain RFX5_N PF18326.1 EAQ91315.1 - 0.042 13.6 0.0 0.094 12.5 0.0 1.6 1 0 0 1 1 1 0 RFX5 N-terminal domain Kdo PF06293.14 EAQ91315.1 - 0.1 12.0 0.1 0.23 10.8 0.0 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3558 PF12079.8 EAQ91315.1 - 0.11 12.4 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3558) ABC2_membrane PF01061.24 EAQ91316.1 - 2.6e-16 59.7 18.5 4.7e-16 58.8 18.5 1.4 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 EAQ91316.1 - 1.5e-14 54.7 0.1 2.7e-14 53.9 0.1 1.4 1 0 0 1 1 1 1 ABC transporter Zn_clus PF00172.18 EAQ91316.1 - 9.1e-06 25.7 2.6 2e-05 24.6 2.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EAQ91316.1 - 9.2e-05 21.6 0.0 0.00043 19.4 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain AAA_16 PF13191.6 EAQ91316.1 - 0.0087 16.5 0.3 0.038 14.4 0.2 2.2 2 0 0 2 2 2 1 AAA ATPase domain NDUFA12 PF05071.16 EAQ91317.1 - 1e-06 29.5 0.3 4.2e-06 27.5 0.0 2.1 2 1 0 2 2 2 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Asp-B-Hydro_N PF05279.11 EAQ91318.1 - 3.7 7.6 33.7 5.4 7.0 33.7 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DNApol_Exo PF18136.1 EAQ91319.1 - 3e-103 344.9 0.0 5.2e-103 344.1 0.0 1.4 1 0 0 1 1 1 1 DNA mitochondrial polymerase exonuclease domain DNA_pol_A PF00476.20 EAQ91319.1 - 7.4e-41 140.5 0.0 1.2e-40 139.8 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family A zf-C3HC4_3 PF13920.6 EAQ91320.1 - 1.4e-11 44.1 7.9 2e-11 43.5 7.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EAQ91320.1 - 1.3e-08 34.5 10.0 2.3e-08 33.7 10.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EAQ91320.1 - 1.9e-08 34.0 9.0 3.5e-08 33.2 9.0 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EAQ91320.1 - 3.4e-07 30.1 8.0 5.3e-07 29.5 8.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 EAQ91320.1 - 4.3e-07 30.2 9.5 7e-07 29.5 9.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EAQ91320.1 - 5.1e-07 29.5 9.6 8.4e-07 28.8 9.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EAQ91320.1 - 4.4e-06 26.6 8.6 1.3e-05 25.1 3.3 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EAQ91320.1 - 0.0038 17.3 8.1 0.0077 16.4 8.1 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 EAQ91320.1 - 0.0039 17.0 5.7 0.0071 16.1 5.7 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 EAQ91320.1 - 0.0045 17.0 3.3 0.0079 16.2 3.3 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 EAQ91320.1 - 0.0089 16.3 5.3 0.02 15.2 5.3 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain Gin PF10764.9 EAQ91320.1 - 0.17 11.9 3.3 0.18 11.8 0.3 2.1 1 1 1 2 2 2 0 Inhibitor of sigma-G Gin zf-RING_11 PF17123.5 EAQ91320.1 - 0.2 11.4 11.1 0.037 13.8 5.9 2.2 2 0 0 2 2 2 0 RING-like zinc finger IBR PF01485.21 EAQ91320.1 - 6.3 7.1 8.1 2.4 8.4 3.3 2.2 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain Nup192 PF11894.8 EAQ91321.1 - 0 1389.9 0.0 4.2e-238 793.3 0.0 2.0 1 1 1 2 2 2 2 Nuclear pore complex scaffold, nucleoporins 186/192/205 Nup188 PF10487.9 EAQ91321.1 - 0.0067 14.4 0.0 0.014 13.4 0.0 1.5 1 0 0 1 1 1 1 Nucleoporin subcomplex protein binding to Pom34 PI3_PI4_kinase PF00454.27 EAQ91322.1 - 5.2e-41 141.1 0.0 1.2e-40 139.9 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.8 EAQ91322.1 - 1.4e-31 109.7 3.7 1.9e-31 109.2 0.0 2.8 2 0 0 2 2 2 1 Telomere-length maintenance and DNA damage repair FAT PF02259.23 EAQ91322.1 - 1.7e-17 63.7 8.8 3.6e-17 62.6 8.8 1.5 1 0 0 1 1 1 1 FAT domain FATC PF02260.20 EAQ91322.1 - 1.1e-11 44.3 0.1 4e-11 42.5 0.1 2.0 1 0 0 1 1 1 1 FATC domain Connexin43 PF03508.13 EAQ91322.1 - 0.21 11.1 0.9 0.49 10.0 0.9 1.5 1 0 0 1 1 1 0 Gap junction alpha-1 protein (Cx43) SNF5 PF04855.12 EAQ91323.1 - 5e-45 154.1 2.6 1.8e-43 149.1 2.6 2.8 1 1 0 1 1 1 1 SNF5 / SMARCB1 / INI1 TPR_18 PF13512.6 EAQ91323.1 - 0.11 12.6 1.8 1.8 8.7 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat MRC1 PF09444.10 EAQ91323.1 - 0.14 12.7 0.2 0.14 12.7 0.2 2.0 2 0 0 2 2 2 0 MRC1-like domain Peptidase_M24 PF00557.24 EAQ91324.1 - 7.8e-06 25.7 0.0 1.1e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 PHD PF00628.29 EAQ91325.1 - 2.1e-14 53.1 15.4 3.6e-08 33.2 7.5 2.4 2 0 0 2 2 2 2 PHD-finger Trypan_PARP PF05887.11 EAQ91325.1 - 0.0036 17.3 35.0 0.0036 17.3 35.0 4.9 4 1 2 6 6 6 1 Procyclic acidic repetitive protein (PARP) C1_1 PF00130.22 EAQ91325.1 - 0.014 15.2 7.6 0.42 10.5 0.5 2.5 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-HC5HC2H PF13771.6 EAQ91325.1 - 0.014 15.6 7.3 0.18 12.1 3.0 2.5 2 0 0 2 2 2 0 PHD-like zinc-binding domain zf-PHD-like PF15446.6 EAQ91325.1 - 0.035 13.7 9.8 0.12 12.0 3.6 2.7 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain PHD_2 PF13831.6 EAQ91325.1 - 0.38 10.4 13.0 0.51 9.9 0.1 3.2 3 0 0 3 3 3 0 PHD-finger zf-HC5HC2H_2 PF13832.6 EAQ91325.1 - 0.47 10.6 5.4 3 8.0 1.7 2.4 2 0 0 2 2 2 0 PHD-zinc-finger like domain PUF PF00806.19 EAQ91327.1 - 3.3e-28 95.8 0.0 0.00011 21.7 0.0 5.9 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat RRM_1 PF00076.22 EAQ91327.1 - 3e-14 52.6 0.0 6.1e-14 51.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spt20 PF12090.8 EAQ91327.1 - 6.2 6.4 10.5 15 5.1 10.5 1.6 1 0 0 1 1 1 0 Spt20 family Pkinase PF00069.25 EAQ91329.1 - 1.5e-47 162.2 0.0 1.8e-47 161.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ91329.1 - 4e-33 114.8 0.0 4.9e-33 114.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EAQ91329.1 - 9.3e-07 28.0 0.0 1.3e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EAQ91329.1 - 1.3e-06 27.9 0.0 1.6e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 EAQ91329.1 - 0.0041 16.2 0.1 0.0056 15.8 0.1 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.23 EAQ91329.1 - 0.0053 16.7 0.0 0.007 16.3 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EAQ91329.1 - 0.015 14.2 0.1 0.022 13.7 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain KIND PF16474.5 EAQ91329.1 - 0.081 12.8 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Kinase non-catalytic C-lobe domain Kdo PF06293.14 EAQ91329.1 - 0.093 12.1 0.1 0.12 11.7 0.1 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HGTP_anticodon PF03129.20 EAQ91331.1 - 1.2e-23 83.1 0.3 5.2e-23 81.0 0.1 2.3 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2b PF00587.25 EAQ91331.1 - 1.7e-07 31.4 0.0 1.1e-06 28.7 0.0 2.2 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) TBPIP_N PF15517.6 EAQ91331.1 - 0.09 12.8 0.1 0.21 11.6 0.1 1.6 1 0 0 1 1 1 0 TBP-interacting protein N-terminus Brix PF04427.18 EAQ91332.1 - 1.2e-21 77.7 0.0 1.9e-21 77.0 0.0 1.2 1 0 0 1 1 1 1 Brix domain Tankyrase_bdg_C PF15327.6 EAQ91332.1 - 0.019 15.4 1.3 0.019 15.4 1.3 2.0 1 1 1 2 2 2 0 Tankyrase binding protein C terminal domain BURP PF03181.15 EAQ91332.1 - 0.24 11.0 0.0 0.43 10.1 0.0 1.3 1 0 0 1 1 1 0 BURP domain Roughex PF06020.11 EAQ91332.1 - 0.96 8.5 14.6 0.31 10.1 11.6 1.6 1 1 1 2 2 2 0 Drosophila roughex protein Denso_VP4 PF02336.15 EAQ91334.1 - 0.23 10.3 0.0 0.46 9.3 0.0 1.4 1 0 0 1 1 1 0 Capsid protein VP4 GDP_Man_Dehyd PF16363.5 EAQ91335.1 - 6.3e-63 213.2 0.2 3.9e-48 164.6 0.1 2.0 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EAQ91335.1 - 1.3e-49 168.8 0.0 5.2e-49 166.9 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EAQ91335.1 - 1.4e-19 70.2 0.0 1.9e-19 69.7 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 EAQ91335.1 - 4.1e-19 68.8 0.0 4.2e-18 65.5 0.0 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 EAQ91335.1 - 6.7e-18 64.8 0.1 1.3e-16 60.6 0.1 2.1 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.17 EAQ91335.1 - 1.1e-13 50.9 0.0 3.2e-13 49.4 0.0 1.6 2 0 0 2 2 2 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 EAQ91335.1 - 5.7e-07 29.6 0.0 1.7e-06 28.1 0.0 1.8 2 0 0 2 2 2 1 NAD(P)H-binding adh_short PF00106.25 EAQ91335.1 - 0.024 14.1 0.0 1.6 8.1 0.1 2.3 2 0 0 2 2 2 0 short chain dehydrogenase Methyltransf_23 PF13489.6 EAQ91336.1 - 2e-13 50.5 0.0 3.5e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAQ91336.1 - 1.2e-08 35.5 0.0 3e-08 34.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EAQ91336.1 - 4.1e-07 30.7 0.0 1.2e-06 29.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAQ91336.1 - 4e-05 23.5 0.0 0.00014 21.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EAQ91336.1 - 5.5e-05 23.7 0.0 0.00013 22.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 EAQ91336.1 - 0.002 18.2 0.0 0.054 13.6 0.0 2.3 1 1 1 2 2 2 1 FtsJ-like methyltransferase Methyltransf_2 PF00891.18 EAQ91336.1 - 0.0026 17.1 0.0 0.0045 16.3 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_4 PF02390.17 EAQ91336.1 - 0.0031 17.0 0.0 0.006 16.1 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Ubie_methyltran PF01209.18 EAQ91336.1 - 0.013 14.8 0.0 0.028 13.8 0.0 1.5 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family CMAS PF02353.20 EAQ91336.1 - 0.08 12.2 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase MTS PF05175.14 EAQ91336.1 - 0.1 12.1 0.0 0.25 10.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase small domain Pep3_Vps18 PF05131.14 EAQ91337.1 - 6.9e-49 165.5 0.0 2.1e-48 164.0 0.0 1.9 2 0 0 2 2 1 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 EAQ91337.1 - 8.1e-11 42.0 2.8 5.9e-07 29.4 0.0 3.4 3 0 0 3 3 3 2 Region in Clathrin and VPS Zn_ribbon_17 PF17120.5 EAQ91337.1 - 0.0021 17.6 0.4 0.0042 16.7 0.4 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 EAQ91337.1 - 0.003 17.5 1.2 0.0058 16.6 1.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EAQ91337.1 - 0.0031 17.3 0.5 0.0079 16.0 0.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EAQ91337.1 - 0.0031 17.2 1.9 0.0083 15.8 1.9 1.7 1 0 0 1 1 1 1 RING-like zinc finger DUF2175 PF09943.9 EAQ91337.1 - 0.0062 16.8 0.3 0.028 14.7 0.1 2.2 2 0 0 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2175) DNA_pol3_theta PF06440.11 EAQ91337.1 - 0.022 14.4 0.0 0.059 13.0 0.0 1.7 1 0 0 1 1 1 0 DNA polymerase III, theta subunit zf-RING_2 PF13639.6 EAQ91337.1 - 0.035 14.4 0.9 0.077 13.3 0.9 1.6 1 0 0 1 1 1 0 Ring finger domain zf-RING_UBOX PF13445.6 EAQ91337.1 - 0.038 14.0 0.2 0.084 12.9 0.2 1.5 1 0 0 1 1 1 0 RING-type zinc-finger Vps39_2 PF10367.9 EAQ91337.1 - 0.044 14.2 0.0 0.17 12.3 0.0 2.1 2 0 0 2 2 1 0 Vacuolar sorting protein 39 domain 2 zf-C3H2C3 PF17122.5 EAQ91337.1 - 0.064 13.3 1.4 0.13 12.4 1.4 1.5 1 0 0 1 1 1 0 Zinc-finger zf-rbx1 PF12678.7 EAQ91337.1 - 0.065 13.5 0.1 0.15 12.4 0.1 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain TPR_7 PF13176.6 EAQ91337.1 - 0.086 12.9 0.5 22 5.4 0.0 4.2 4 0 0 4 4 3 0 Tetratricopeptide repeat zf-C3HC4 PF00097.25 EAQ91337.1 - 3.7 7.5 4.7 0.73 9.7 0.8 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Asp PF00026.23 EAQ91338.1 - 5.9e-60 203.3 0.0 1.9e-59 201.7 0.0 1.7 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EAQ91338.1 - 3.6e-14 53.4 0.3 1.8e-11 44.6 0.2 3.4 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EAQ91338.1 - 1.1e-08 35.6 0.6 0.0032 18.1 0.1 3.6 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 EAQ91338.1 - 0.001 19.6 0.0 4.3 8.0 0.0 3.4 2 1 0 2 2 2 2 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 EAQ91338.1 - 0.031 14.0 0.0 0.064 13.0 0.0 1.6 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal NmrA PF05368.13 EAQ91339.1 - 9e-11 41.8 0.0 4.7e-10 39.4 0.0 2.1 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EAQ91339.1 - 1.1e-08 35.1 0.1 1.9e-08 34.4 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 EAQ91339.1 - 2.2e-05 24.7 0.0 3.6e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 EAQ91339.1 - 0.0012 18.4 0.1 0.0048 16.4 0.1 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family GFO_IDH_MocA PF01408.22 EAQ91339.1 - 0.0027 18.5 0.0 0.0047 17.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold KR PF08659.10 EAQ91339.1 - 0.016 15.2 0.2 0.023 14.6 0.2 1.3 1 0 0 1 1 1 0 KR domain Pigment_DH PF06324.11 EAQ91339.1 - 0.76 10.0 0.1 0.76 10.0 0.1 2.0 2 0 0 2 2 2 0 Pigment-dispersing hormone (PDH) zf-BED PF02892.15 EAQ91340.1 - 0.00095 19.1 1.2 0.0023 17.9 0.4 2.1 2 0 0 2 2 2 1 BED zinc finger zf-RING_10 PF16685.5 EAQ91340.1 - 0.023 14.9 0.1 0.053 13.7 0.1 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 DUF1660 PF07874.11 EAQ91340.1 - 0.084 13.4 0.8 2.9 8.5 0.1 2.7 2 0 0 2 2 2 0 Prophage protein (DUF1660) Glycoprot_B_PH2 PF17417.2 EAQ91340.1 - 0.098 13.0 0.8 0.22 11.8 0.5 1.8 1 1 0 1 1 1 0 Herpesvirus Glycoprotein B PH-like domain WD40 PF00400.32 EAQ91341.1 - 8.6e-19 67.5 5.5 3.2e-05 24.6 0.0 5.5 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAQ91341.1 - 5.4e-11 42.6 0.1 0.011 16.0 0.0 4.4 2 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EAQ91341.1 - 0.0042 16.5 0.0 0.0069 15.8 0.0 1.3 1 0 0 1 1 1 1 WD40-like domain Rrn6 PF10214.9 EAQ91341.1 - 0.017 13.7 0.1 0.025 13.1 0.1 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor PQQ_3 PF13570.6 EAQ91341.1 - 0.046 14.2 1.4 10 6.7 0.0 4.4 5 0 0 5 5 5 0 PQQ-like domain PUF PF00806.19 EAQ91342.1 - 1.1e-52 172.8 0.6 2.6e-08 33.1 0.0 7.4 7 0 0 7 7 7 7 Pumilio-family RNA binding repeat HypD PF01924.16 EAQ91342.1 - 0.0092 15.1 0.1 0.014 14.5 0.1 1.2 1 0 0 1 1 1 1 Hydrogenase formation hypA family CPL PF08144.11 EAQ91342.1 - 0.075 13.4 4.2 10 6.5 0.0 4.0 2 2 1 3 3 3 0 CPL (NUC119) domain DUF3377 PF11857.8 EAQ91343.1 - 0.0028 17.5 0.6 0.0086 16.0 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3377) 7tm_7 PF08395.12 EAQ91343.1 - 0.021 14.1 0.2 0.025 13.8 0.2 1.0 1 0 0 1 1 1 0 7tm Chemosensory receptor EphA2_TM PF14575.6 EAQ91343.1 - 0.022 15.6 0.0 0.034 15.0 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Herpes_gE PF02480.16 EAQ91343.1 - 0.044 12.5 0.0 0.074 11.8 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E TMEM51 PF15345.6 EAQ91343.1 - 0.045 13.6 0.2 0.099 12.5 0.1 1.6 2 0 0 2 2 2 0 Transmembrane protein 51 BiPBP_C PF06832.12 EAQ91343.1 - 0.091 12.8 0.0 0.23 11.5 0.0 1.7 1 0 0 1 1 1 0 Penicillin-Binding Protein C-terminus Family Cation_efflux PF01545.21 EAQ91343.1 - 0.092 12.5 0.0 0.096 12.4 0.0 1.1 1 0 0 1 1 1 0 Cation efflux family IgaA PF07095.11 EAQ91343.1 - 0.1 10.6 0.1 0.13 10.3 0.1 1.1 1 0 0 1 1 1 0 Intracellular growth attenuator protein IgaA DUF5305 PF17231.2 EAQ91343.1 - 0.16 11.4 0.0 0.28 10.6 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5305) DUF4366 PF14283.6 EAQ91343.1 - 0.16 12.0 0.1 5 7.2 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4366) SARAF PF06682.12 EAQ91343.1 - 0.21 11.2 0.0 0.24 11.0 0.0 1.1 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Phosphodiest PF01663.22 EAQ91344.1 - 5e-15 56.0 0.3 1.6e-14 54.3 0.2 1.9 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 EAQ91344.1 - 0.00024 20.6 0.0 0.00044 19.7 0.0 1.5 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.18 EAQ91344.1 - 0.0035 16.7 0.5 0.0064 15.9 0.5 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily Meth_synt_2 PF01717.18 EAQ91346.1 - 1.1e-146 488.3 0.0 1.4e-142 474.7 0.0 2.3 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 EAQ91346.1 - 7.7e-109 364.0 0.0 5.6e-103 344.7 0.0 2.8 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain URO-D PF01208.17 EAQ91346.1 - 0.0014 17.9 0.0 1.1 8.4 0.0 2.5 2 0 0 2 2 2 2 Uroporphyrinogen decarboxylase (URO-D) EF-hand_4 PF12763.7 EAQ91347.1 - 5.5e-25 87.3 0.0 2e-13 50.2 0.0 2.5 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand WH2 PF02205.20 EAQ91347.1 - 6.3e-06 25.8 0.5 2.2e-05 24.1 0.5 2.0 1 0 0 1 1 1 1 WH2 motif EF-hand_7 PF13499.6 EAQ91347.1 - 0.00018 21.9 0.4 0.37 11.3 0.0 3.2 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 EAQ91347.1 - 0.00027 20.3 0.0 0.52 10.0 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 EAQ91347.1 - 0.0011 18.8 0.0 3.7 7.7 0.0 3.5 3 0 0 3 3 3 1 EF-hand domain DUF1720 PF08226.11 EAQ91347.1 - 0.0059 17.0 15.4 0.0059 17.0 15.4 6.9 5 3 2 7 7 7 3 Domain of unknown function (DUF1720) E3_binding PF02817.17 EAQ91347.1 - 0.014 15.7 0.2 0.14 12.5 0.1 2.6 2 0 0 2 2 2 0 e3 binding domain Forkhead PF00250.18 EAQ91348.1 - 1.6e-35 121.2 0.4 3.8e-35 120.0 0.2 1.8 2 0 0 2 2 2 1 Forkhead domain ATG101 PF07855.12 EAQ91349.1 - 5.5e-52 175.9 0.0 6.6e-52 175.6 0.0 1.1 1 0 0 1 1 1 1 Autophagy-related protein 101 Peroxin-3 PF04882.12 EAQ91350.1 - 4.8e-159 530.3 0.0 5.5e-159 530.1 0.0 1.0 1 0 0 1 1 1 1 Peroxin-3 Med3 PF11593.8 EAQ91350.1 - 0.19 10.9 5.1 0.3 10.2 5.1 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal TauD PF02668.16 EAQ91351.1 - 0.02 14.7 4.0 0.19 11.5 0.0 2.4 2 1 0 2 2 2 0 Taurine catabolism dioxygenase TauD, TfdA family Sybindin PF04099.12 EAQ91352.1 - 2.5e-23 82.6 0.0 3.3e-23 82.2 0.0 1.2 1 0 0 1 1 1 1 Sybindin-like family Pkinase PF00069.25 EAQ91353.1 - 3.7e-52 177.3 0.0 5.3e-52 176.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ91353.1 - 2.5e-34 118.7 0.0 3.4e-34 118.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAQ91353.1 - 4.5e-08 32.7 0.0 6.3e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EAQ91353.1 - 4.6e-05 23.5 0.2 0.00013 21.9 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EAQ91353.1 - 0.0045 15.8 0.9 0.0076 15.1 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 EAQ91353.1 - 0.12 11.7 0.0 0.33 10.3 0.0 1.6 1 1 1 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 EAQ91355.1 - 2e-39 135.5 0.0 2.6e-39 135.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ91355.1 - 7e-26 91.1 0.0 9.3e-26 90.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EAQ91355.1 - 0.0023 17.3 0.0 0.0033 16.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EAQ91355.1 - 0.024 14.0 0.0 0.034 13.5 0.0 1.2 1 0 0 1 1 1 0 Kinase-like RIO1 PF01163.22 EAQ91355.1 - 0.046 13.3 0.0 0.086 12.4 0.0 1.3 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 EAQ91355.1 - 0.15 11.9 0.0 0.67 9.8 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family Menin PF05053.13 EAQ91357.1 - 0.13 10.6 0.7 0.19 10.1 0.7 1.1 1 0 0 1 1 1 0 Menin RNA_pol_L_2 PF13656.6 EAQ91358.1 - 1e-31 108.5 0.0 1.4e-31 108.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 EAQ91358.1 - 3.6e-13 48.7 0.0 5.4e-13 48.2 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Complex1_LYR_2 PF13233.6 EAQ91359.1 - 6.5e-05 23.6 0.2 0.0001 23.0 0.2 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 EAQ91359.1 - 0.0058 16.7 0.3 0.022 14.8 0.0 1.9 2 0 0 2 2 2 1 Complex 1 protein (LYR family) G10 PF01125.17 EAQ91360.1 - 1.3e-63 213.1 2.8 1.4e-63 213.0 2.8 1.0 1 0 0 1 1 1 1 G10 protein Auto_anti-p27 PF06677.12 EAQ91360.1 - 0.023 14.8 2.3 0.023 14.8 2.3 1.9 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Actin_micro PF17003.5 EAQ91361.1 - 0.0078 15.4 0.1 0.0088 15.3 0.1 1.2 1 0 0 1 1 1 1 Putative actin-like family DUF629 PF04780.12 EAQ91361.1 - 1 7.8 4.5 0.97 7.9 0.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF629) zf-C2H2 PF00096.26 EAQ91361.1 - 2.1 9.0 12.5 6.5 7.4 0.2 3.4 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EAQ91361.1 - 8 7.6 9.1 13 6.9 0.2 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger EST1_DNA_bind PF10373.9 EAQ91362.1 - 7e-51 173.4 0.0 1e-50 172.8 0.0 1.3 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.9 EAQ91362.1 - 2.3e-20 73.6 0.3 5.3e-20 72.4 0.3 1.7 1 0 0 1 1 1 1 Telomerase activating protein Est1 GyrB_insert PF18053.1 EAQ91362.1 - 0.15 12.0 0.1 0.35 10.7 0.1 1.5 1 0 0 1 1 1 0 DNA gyrase B subunit insert domain PfkB PF00294.24 EAQ91363.1 - 8.2e-66 222.3 0.0 9.3e-66 222.2 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 EAQ91363.1 - 0.00069 19.1 0.0 0.0011 18.4 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Lyase_1 PF00206.20 EAQ91364.1 - 4e-86 289.2 0.0 5.4e-86 288.8 0.0 1.1 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.6 EAQ91364.1 - 1.7e-23 83.1 0.1 4.5e-23 81.8 0.1 1.7 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal SHOCT PF09851.9 EAQ91364.1 - 0.14 11.9 0.4 0.63 9.9 0.1 2.3 2 0 0 2 2 2 0 Short C-terminal domain Ribosomal_L2_C PF03947.18 EAQ91365.1 - 7.9e-18 64.9 3.0 9.2e-18 64.7 3.0 1.1 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain WHIM1 PF15612.6 EAQ91366.1 - 1.7e-07 30.6 0.0 3.6e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 DUF1770 PF08589.10 EAQ91367.1 - 6.7e-37 126.5 0.3 8.2e-37 126.2 0.3 1.1 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1770) eRF1_2 PF03464.15 EAQ91368.1 - 2.9e-46 157.1 0.1 5e-46 156.3 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 EAQ91368.1 - 7.2e-41 139.2 0.7 1.5e-40 138.2 0.7 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 EAQ91368.1 - 1.7e-21 76.6 0.0 2.7e-21 75.9 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 baeRF_family10 PF18854.1 EAQ91368.1 - 1.2e-10 41.8 0.2 4.2e-10 40.0 0.0 1.9 2 0 0 2 2 2 1 Bacterial archaeo-eukaryotic release factor family 10 acVLRF1 PF18859.1 EAQ91368.1 - 7.4e-09 36.0 0.0 1.2e-08 35.3 0.0 1.3 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor PDT PF00800.18 EAQ91369.1 - 2.3e-18 66.6 0.0 2.9e-18 66.3 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydratase zf-RVT PF13966.6 EAQ91370.1 - 0.08 13.7 0.0 0.22 12.2 0.0 1.7 2 0 0 2 2 2 0 zinc-binding in reverse transcriptase MaoC_dehydratas PF01575.19 EAQ91371.1 - 0.029 13.9 0.0 0.068 12.7 0.0 1.6 1 0 0 1 1 1 0 MaoC like domain LRR_1 PF00560.33 EAQ91372.1 - 0.063 13.9 8.4 58 4.8 0.0 7.8 9 0 0 9 9 9 0 Leucine Rich Repeat Pkinase PF00069.25 EAQ91374.1 - 3.9e-69 232.9 0.0 8.4e-69 231.9 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ91374.1 - 1.8e-49 168.4 0.0 3e-49 167.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.6 EAQ91374.1 - 7.2e-28 96.9 0.0 1.8e-27 95.6 0.0 1.7 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_2 PF07647.17 EAQ91374.1 - 8e-16 57.9 0.2 3.2e-15 56.0 0.0 2.0 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 EAQ91374.1 - 5e-15 55.7 0.0 9.5e-15 54.8 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.23 EAQ91374.1 - 1.7e-13 51.0 0.0 3e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Kinase-like PF14531.6 EAQ91374.1 - 1.5e-07 31.1 0.0 0.00013 21.4 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 EAQ91374.1 - 0.026 13.3 0.0 0.044 12.5 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase SAM_4 PF18017.1 EAQ91374.1 - 0.039 13.9 0.0 0.087 12.8 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 EAQ91374.1 - 0.064 13.2 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain Ank_2 PF12796.7 EAQ91377.1 - 3.7e-148 482.5 57.5 4.9e-17 62.3 0.2 11.0 2 2 9 12 12 12 12 Ankyrin repeats (3 copies) Ank PF00023.30 EAQ91377.1 - 5.8e-97 314.3 53.6 0.0017 18.8 0.1 22.6 22 0 0 22 22 22 20 Ankyrin repeat Ank_4 PF13637.6 EAQ91377.1 - 1.6e-96 315.5 26.2 7.9e-08 32.7 0.2 19.7 1 1 19 21 21 21 21 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAQ91377.1 - 3.4e-71 234.4 25.0 3.1e-06 27.4 0.2 18.6 2 2 18 20 20 20 20 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAQ91377.1 - 7.1e-52 167.3 22.4 0.58 10.9 0.0 22.3 22 0 0 22 22 22 12 Ankyrin repeat RVT_1 PF00078.27 EAQ91377.1 - 9.6e-13 48.1 0.0 2.8e-12 46.6 0.0 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PNP_UDP_1 PF01048.20 EAQ91377.1 - 4.7e-07 29.3 0.1 1.5e-06 27.7 0.1 1.8 1 1 0 1 1 1 1 Phosphorylase superfamily Exo_endo_phos_2 PF14529.6 EAQ91377.1 - 1.8e-06 27.8 0.0 6.4e-05 22.8 0.0 3.6 4 0 0 4 4 4 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 EAQ91377.1 - 0.001 18.6 0.0 0.0036 16.9 0.0 2.0 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family NACHT PF05729.12 EAQ91377.1 - 0.0025 17.7 0.1 0.006 16.5 0.1 1.5 1 0 0 1 1 1 1 NACHT domain DUF5444 PF17519.2 EAQ91377.1 - 0.0055 16.7 0.4 23 5.1 0.0 4.4 4 1 0 4 4 4 0 Family of unknown function (DUF5444) HTH_IclR PF09339.10 EAQ91377.1 - 0.27 11.0 1.1 1.5 8.7 0.2 2.7 2 0 0 2 2 2 0 IclR helix-turn-helix domain K_oxygenase PF13434.6 EAQ91379.1 - 0.0013 17.9 0.0 0.0018 17.5 0.0 1.2 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.12 EAQ91379.1 - 0.0051 15.9 0.2 0.0079 15.3 0.2 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 EAQ91379.1 - 0.0095 15.2 0.0 0.017 14.4 0.0 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 EAQ91379.1 - 0.011 15.8 1.5 0.043 13.8 1.5 2.0 1 1 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 EAQ91379.1 - 0.02 14.1 0.0 0.031 13.5 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 EAQ91379.1 - 0.03 14.0 0.0 0.047 13.3 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_8 PF13450.6 EAQ91379.1 - 0.034 14.4 0.0 0.13 12.5 0.0 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EAQ91379.1 - 0.045 13.0 0.0 0.071 12.3 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EAQ91379.1 - 0.093 12.0 0.1 0.16 11.2 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Zip PF02535.22 EAQ91380.1 - 5e-30 104.9 38.7 3.7e-12 46.1 7.5 3.2 2 1 1 3 3 3 3 ZIP Zinc transporter FSA_C PF10479.9 EAQ91381.1 - 9.5 4.2 6.1 14 3.6 6.1 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Zip PF02535.22 EAQ91383.1 - 2.3e-13 50.1 12.7 5.3e-07 29.2 2.3 2.6 1 1 2 3 3 3 2 ZIP Zinc transporter Jiraiya PF15038.6 EAQ91383.1 - 0.036 13.5 1.5 0.13 11.7 0.2 2.3 2 0 0 2 2 2 0 Jiraiya PetM PF08041.11 EAQ91383.1 - 0.13 11.8 0.4 0.13 11.8 0.4 3.3 3 0 0 3 3 3 0 PetM family of cytochrome b6f complex subunit 7 DUF4395 PF14340.6 EAQ91383.1 - 0.5 10.7 7.1 0.31 11.4 3.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4395) Sas10 PF09368.10 EAQ91384.1 - 2.6e-31 107.9 7.8 2.6e-31 107.9 7.8 3.1 5 0 0 5 5 5 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 EAQ91384.1 - 1.1e-11 45.2 0.3 3.2e-10 40.5 0.0 2.8 2 0 0 2 2 2 1 Sas10/Utp3/C1D family adh_short PF00106.25 EAQ91385.1 - 2e-27 95.9 0.0 4.8e-27 94.7 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EAQ91385.1 - 2.3e-17 63.4 0.0 5.4e-17 62.1 0.0 1.6 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF3716 PF12511.8 EAQ91385.1 - 5.8e-16 58.3 8.3 9.3e-16 57.6 8.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) KR PF08659.10 EAQ91385.1 - 5e-07 29.8 0.1 1.9e-06 27.9 0.1 2.0 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.8 EAQ91385.1 - 0.039 13.7 0.1 0.13 12.1 0.1 1.8 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase THF_DHG_CYH_C PF02882.19 EAQ91385.1 - 0.099 12.0 0.0 0.25 10.7 0.0 1.6 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain SelP_N PF04592.14 EAQ91385.1 - 3.2 7.1 25.8 2.3 7.6 14.6 2.3 2 0 0 2 2 2 0 Selenoprotein P, N terminal region G-alpha PF00503.20 EAQ91386.1 - 1.7e-123 412.3 1.8 2e-123 412.1 1.8 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EAQ91386.1 - 2.3e-15 56.5 1.3 3.7e-10 39.5 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family zf-CHC2 PF01807.20 EAQ91386.1 - 0.00019 21.1 0.0 0.00085 19.1 0.0 1.9 2 0 0 2 2 2 1 CHC2 zinc finger Gtr1_RagA PF04670.12 EAQ91386.1 - 0.00064 19.1 2.5 0.089 12.1 0.0 2.7 2 1 0 3 3 3 2 Gtr1/RagA G protein conserved region AAA_29 PF13555.6 EAQ91386.1 - 0.0095 15.7 0.1 0.071 12.9 0.1 2.2 1 1 1 2 2 2 1 P-loop containing region of AAA domain Roc PF08477.13 EAQ91386.1 - 0.011 16.0 0.2 1.3 9.2 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase MCM PF00493.23 EAQ91386.1 - 0.014 14.5 0.1 0.029 13.5 0.1 1.6 1 1 0 1 1 1 0 MCM P-loop domain MMR_HSR1 PF01926.23 EAQ91386.1 - 0.069 13.2 0.1 12 6.0 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 EAQ91386.1 - 0.12 11.8 0.0 0.26 10.6 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF1771 PF08590.10 EAQ91387.1 - 9.3e-22 77.2 8.9 2.5e-21 75.8 8.9 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.21 EAQ91387.1 - 4.6e-12 46.1 0.3 1.3e-11 44.7 0.3 1.8 1 0 0 1 1 1 1 Smr domain DUF4407 PF14362.6 EAQ91387.1 - 0.066 12.5 3.1 0.1 11.9 3.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Connexin43 PF03508.13 EAQ91387.1 - 0.26 10.9 1.2 0.51 9.9 1.2 1.5 1 0 0 1 1 1 0 Gap junction alpha-1 protein (Cx43) BBP2 PF07642.11 EAQ91388.1 - 0.015 14.4 0.2 0.021 14.0 0.2 1.0 1 0 0 1 1 1 0 Putative beta-barrel porin-2, OmpL-like. bbp2 DUF5305 PF17231.2 EAQ91388.1 - 0.045 13.1 0.0 0.055 12.9 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5305) DUF543 PF04418.12 EAQ91389.1 - 6.4e-30 103.0 0.0 7.4e-30 102.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) FTR1 PF03239.14 EAQ91389.1 - 0.059 12.5 0.0 0.078 12.1 0.0 1.1 1 0 0 1 1 1 0 Iron permease FTR1 family Urb2 PF10441.9 EAQ91390.1 - 8.1e-70 234.9 0.2 2.2e-69 233.5 0.2 1.8 1 0 0 1 1 1 1 Urb2/Npa2 family ERAP1_C PF11838.8 EAQ91390.1 - 0.00034 20.3 0.7 0.0012 18.4 0.4 2.2 2 0 0 2 2 2 1 ERAP1-like C-terminal domain D123 PF07065.14 EAQ91391.1 - 6.7e-111 370.3 0.5 8.5e-111 370.0 0.5 1.1 1 0 0 1 1 1 1 D123 HCMV_UL139 PF12507.8 EAQ91391.1 - 0.061 13.7 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 Human Cytomegalovirus UL139 protein cwf21 PF08312.12 EAQ91392.1 - 6.9e-17 61.3 15.4 2.1e-16 59.8 15.4 1.9 1 0 0 1 1 1 1 cwf21 domain Trans_reg_C PF00486.28 EAQ91392.1 - 0.037 14.1 0.3 0.76 9.9 0.1 2.5 1 1 1 2 2 2 0 Transcriptional regulatory protein, C terminal GvpG PF05120.12 EAQ91392.1 - 8.8 6.4 14.1 3.6 7.7 4.3 2.4 2 1 0 2 2 2 0 Gas vesicle protein G RasGEF PF00617.19 EAQ91393.1 - 1.8e-56 191.2 0.0 9.5e-56 188.8 0.0 2.2 1 1 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 EAQ91393.1 - 7.9e-28 96.8 0.5 1.9e-27 95.6 0.5 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.28 EAQ91393.1 - 1.1e-15 56.9 0.1 2.5e-15 55.8 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EAQ91393.1 - 1.3e-13 50.6 0.1 2.6e-13 49.6 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EAQ91393.1 - 6.3e-13 48.2 0.1 1.4e-12 47.1 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.26 EAQ91393.1 - 7.5e-05 22.7 0.0 0.00016 21.6 0.0 1.6 1 0 0 1 1 1 1 WW domain DUF1944 PF09175.10 EAQ91393.1 - 0.02 14.7 0.0 0.065 13.1 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1944) zf-H2C2_2 PF13465.6 EAQ91395.1 - 3.7e-08 33.4 12.2 1.1e-05 25.7 5.8 3.0 2 0 0 2 2 2 2 Zinc-finger double domain Fungal_trans PF04082.18 EAQ91395.1 - 3.5e-07 29.5 0.7 6e-06 25.5 0.3 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 EAQ91395.1 - 0.00063 20.1 14.6 0.037 14.5 5.3 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EAQ91395.1 - 0.0013 19.3 12.7 0.25 12.3 4.1 3.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 EAQ91395.1 - 0.015 16.0 0.4 1.7 9.3 0.9 2.9 2 1 1 3 3 3 0 Zinc finger C2H2-type, 3 repeats Phage_lysozyme2 PF18013.1 EAQ91395.1 - 0.15 12.0 0.1 0.35 10.9 0.1 1.6 1 0 0 1 1 1 0 Phage tail lysozyme Zn-ribbon_8 PF09723.10 EAQ91395.1 - 1.4 9.1 4.1 3.8 7.7 4.1 1.8 1 0 0 1 1 1 0 Zinc ribbon domain zf-C2H2_jaz PF12171.8 EAQ91395.1 - 2.8 8.4 7.7 1.3 9.4 3.7 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Glyco_hydro_16 PF00722.21 EAQ91396.1 - 1.2e-11 44.5 0.0 2.7e-11 43.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 HEAT PF02985.22 EAQ91397.1 - 9.6e-06 25.4 8.9 1.2 9.6 0.1 7.1 9 0 0 9 9 9 2 HEAT repeat HEAT_2 PF13646.6 EAQ91397.1 - 0.00067 20.0 2.6 0.011 16.1 0.2 5.2 5 1 1 6 6 6 2 HEAT repeats Cnd1 PF12717.7 EAQ91397.1 - 0.0053 16.8 0.3 26 4.8 0.0 5.0 4 1 0 5 5 5 1 non-SMC mitotic condensation complex subunit 1 CBF PF03914.17 EAQ91397.1 - 0.022 14.8 0.3 0.083 12.9 0.3 2.0 1 0 0 1 1 1 0 CBF/Mak21 family HEAT_EZ PF13513.6 EAQ91397.1 - 0.094 13.2 4.7 53 4.5 0.0 5.1 5 0 0 5 5 5 0 HEAT-like repeat RVT_1 PF00078.27 EAQ91398.1 - 1.4e-36 126.1 0.0 2.1e-36 125.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Homeobox_KN PF05920.11 EAQ91399.1 - 0.0024 17.8 0.2 0.0047 16.8 0.2 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 EAQ91399.1 - 0.0059 16.4 0.1 0.015 15.1 0.1 1.7 1 0 0 1 1 1 1 Homeodomain DnaB_2 PF07261.11 EAQ91399.1 - 0.13 12.0 0.0 0.9 9.3 0.0 2.0 2 0 0 2 2 2 0 Replication initiation and membrane attachment Transposase_mut PF00872.18 EAQ91401.1 - 0.033 13.1 0.0 0.044 12.6 0.0 1.1 1 0 0 1 1 1 0 Transposase, Mutator family Rhodanese PF00581.20 EAQ91402.1 - 2.5e-07 31.2 0.0 6.6e-07 29.8 0.0 1.8 1 0 0 1 1 1 1 Rhodanese-like domain Peptidase_C14 PF00656.22 EAQ91402.1 - 0.044 13.7 0.0 0.28 11.1 0.0 2.0 1 1 0 1 1 1 0 Caspase domain DUF4372 PF14294.6 EAQ91402.1 - 0.12 12.5 0.1 0.39 10.9 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4372) PIG-X PF08320.12 EAQ91403.1 - 1.4e-37 129.7 0.0 2e-37 129.2 0.0 1.2 1 0 0 1 1 1 1 PIG-X / PBN1 Sulfotransfer_3 PF13469.6 EAQ91404.1 - 0.0022 18.4 0.3 0.25 11.7 0.3 3.1 1 1 0 1 1 1 1 Sulfotransferase family Mhr1 PF12829.7 EAQ91405.1 - 2.5e-29 101.2 0.0 3.8e-29 100.6 0.0 1.3 1 0 0 1 1 1 1 Transcriptional regulation of mitochondrial recombination AAA_2 PF07724.14 EAQ91406.1 - 1.9e-47 161.5 0.0 9.4e-46 156.0 0.0 3.0 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 EAQ91406.1 - 6.1e-34 116.1 11.3 4.2e-33 113.4 2.9 3.5 2 1 1 3 3 3 1 AAA lid domain AAA PF00004.29 EAQ91406.1 - 3.8e-27 95.3 0.0 1e-14 55.1 0.0 3.0 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 EAQ91406.1 - 1.8e-22 79.2 0.9 1.8e-22 79.2 0.9 2.5 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 EAQ91406.1 - 5.6e-16 58.8 0.0 4e-10 39.8 0.0 2.9 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EAQ91406.1 - 4.9e-13 49.5 0.0 5.2e-05 23.5 0.0 4.4 2 1 1 3 3 3 2 AAA domain AAA_16 PF13191.6 EAQ91406.1 - 3.1e-11 44.0 15.3 9.4e-07 29.4 0.1 5.7 4 3 0 5 5 4 2 AAA ATPase domain Sigma54_activat PF00158.26 EAQ91406.1 - 3.5e-09 36.6 0.0 1.2e-05 25.1 0.0 2.8 2 1 0 2 2 2 2 Sigma-54 interaction domain ATPase_2 PF01637.18 EAQ91406.1 - 3.7e-07 30.3 0.1 0.028 14.3 0.1 4.2 3 1 0 3 3 3 1 ATPase domain predominantly from Archaea AAA_14 PF13173.6 EAQ91406.1 - 9.1e-07 29.0 0.0 0.079 13.0 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_7 PF12775.7 EAQ91406.1 - 2.8e-06 27.0 0.0 0.013 15.0 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region IstB_IS21 PF01695.17 EAQ91406.1 - 4.3e-06 26.6 0.0 0.078 12.7 0.0 2.9 3 0 0 3 3 2 2 IstB-like ATP binding protein AAA_18 PF13238.6 EAQ91406.1 - 5.4e-06 27.0 0.0 0.1 13.1 0.0 3.2 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 EAQ91406.1 - 6.7e-06 25.6 0.1 0.17 11.2 0.1 3.5 2 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 EAQ91406.1 - 6.9e-06 26.3 0.0 0.27 11.4 0.0 3.5 2 0 0 2 2 2 2 AAA domain Clp_N PF02861.20 EAQ91406.1 - 1.2e-05 25.3 2.8 0.0052 16.9 0.0 4.0 3 0 0 3 3 3 1 Clp amino terminal domain, pathogenicity island component RNA_helicase PF00910.22 EAQ91406.1 - 5.7e-05 23.5 0.0 0.5 10.8 0.0 2.6 2 0 0 2 2 2 2 RNA helicase AAA_28 PF13521.6 EAQ91406.1 - 8.4e-05 22.9 1.2 0.5 10.6 0.0 3.5 3 0 0 3 3 2 2 AAA domain RuvB_N PF05496.12 EAQ91406.1 - 0.00017 21.4 1.1 3.5 7.4 0.6 4.3 3 1 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 EAQ91406.1 - 0.00022 21.2 0.0 0.33 11.0 0.0 2.6 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 EAQ91406.1 - 0.00025 20.8 0.0 1.1 9.0 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_3 PF07726.11 EAQ91406.1 - 0.0003 20.6 0.0 1.4 8.8 0.0 3.4 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 EAQ91406.1 - 0.0004 20.3 0.0 0.42 10.5 0.0 2.8 2 0 0 2 2 2 1 RsgA GTPase AAA_24 PF13479.6 EAQ91406.1 - 0.00041 20.1 0.0 0.59 9.8 0.0 2.9 2 1 0 2 2 2 1 AAA domain ABC_tran PF00005.27 EAQ91406.1 - 0.00055 20.5 0.4 0.62 10.6 0.0 3.2 3 0 0 3 3 2 1 ABC transporter AAA_29 PF13555.6 EAQ91406.1 - 0.0019 17.9 0.0 1.9 8.3 0.0 2.7 3 0 0 3 3 2 1 P-loop containing region of AAA domain AAA_19 PF13245.6 EAQ91406.1 - 0.0022 18.3 2.7 0.3 11.4 0.1 3.8 5 1 1 6 6 3 1 AAA domain NACHT PF05729.12 EAQ91406.1 - 0.0032 17.4 0.0 0.23 11.4 0.0 2.7 2 0 0 2 2 2 1 NACHT domain NTPase_1 PF03266.15 EAQ91406.1 - 0.0054 16.6 0.0 0.2 11.6 0.0 3.1 3 0 0 3 3 2 1 NTPase Roc PF08477.13 EAQ91406.1 - 0.006 16.8 0.0 2.1 8.6 0.0 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase ResIII PF04851.15 EAQ91406.1 - 0.0064 16.5 0.0 1.4 8.9 0.0 3.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Torsin PF06309.11 EAQ91406.1 - 0.0066 16.5 0.0 0.054 13.6 0.0 2.2 2 0 0 2 2 2 1 Torsin Zeta_toxin PF06414.12 EAQ91406.1 - 0.0075 15.6 0.0 0.66 9.2 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin Rad17 PF03215.15 EAQ91406.1 - 0.012 15.6 0.0 7 6.5 0.0 2.8 2 1 0 2 2 2 0 Rad17 P-loop domain T2SSE PF00437.20 EAQ91406.1 - 0.015 14.4 4.3 0.068 12.2 0.2 3.4 3 1 0 3 3 3 0 Type II/IV secretion system protein GAS PF13851.6 EAQ91406.1 - 0.016 14.5 6.3 0.042 13.2 6.3 1.7 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding SRP54 PF00448.22 EAQ91406.1 - 0.02 14.5 0.0 3.9 7.1 0.0 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain DUF815 PF05673.13 EAQ91406.1 - 0.038 13.1 0.0 2.4 7.2 0.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF815) CbiA PF01656.23 EAQ91406.1 - 0.082 13.0 0.1 47 4.0 0.1 3.7 3 2 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain ATP_bind_1 PF03029.17 EAQ91406.1 - 0.088 12.6 0.0 8.2 6.1 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein V_ATPase_I PF01496.19 EAQ91406.1 - 0.1 10.5 1.6 0.19 9.6 1.6 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PduV-EutP PF10662.9 EAQ91406.1 - 0.11 12.2 0.0 6.8 6.4 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_25 PF13481.6 EAQ91406.1 - 0.17 11.4 4.3 3.9 7.0 0.0 3.4 3 0 0 3 3 3 0 AAA domain AAA_23 PF13476.6 EAQ91406.1 - 0.38 11.2 0.0 0.38 11.2 0.0 4.4 5 1 0 5 5 3 0 AAA domain CHDCT2 PF08074.11 EAQ91406.1 - 0.77 9.9 5.3 1.8 8.7 0.1 3.5 3 1 0 3 3 3 0 CHDCT2 (NUC038) domain Macoilin PF09726.9 EAQ91406.1 - 6.8 5.1 7.9 11 4.4 7.9 1.2 1 0 0 1 1 1 0 Macoilin family PrpF PF04303.13 EAQ91407.1 - 3e-51 174.5 0.1 2.5e-48 164.9 0.1 2.1 1 1 1 2 2 2 2 PrpF protein PQQ_3 PF13570.6 EAQ91407.1 - 0.13 12.8 0.5 2.4 8.8 0.0 2.8 2 0 0 2 2 2 0 PQQ-like domain Fungal_trans_2 PF11951.8 EAQ91408.1 - 0.0027 16.6 0.1 0.0037 16.1 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain DsbD_2 PF13386.6 EAQ91408.1 - 0.008 16.1 0.2 0.013 15.5 0.2 1.2 1 0 0 1 1 1 1 Cytochrome C biogenesis protein transmembrane region TPR_1 PF00515.28 EAQ91409.1 - 2.4e-36 122.1 22.5 6.5e-05 22.6 0.1 12.7 12 0 0 12 12 12 8 Tetratricopeptide repeat TPR_2 PF07719.17 EAQ91409.1 - 2.7e-31 105.1 34.6 0.0024 17.8 0.1 13.4 14 0 0 14 14 13 8 Tetratricopeptide repeat TPR_8 PF13181.6 EAQ91409.1 - 1.2e-29 100.0 19.2 9.6e-05 22.3 0.1 12.7 13 0 0 13 13 12 7 Tetratricopeptide repeat TPR_19 PF14559.6 EAQ91409.1 - 1.1e-17 64.3 36.1 0.0012 19.3 0.0 11.3 8 4 2 11 11 11 5 Tetratricopeptide repeat TPR_12 PF13424.6 EAQ91409.1 - 2.5e-16 59.7 42.3 0.00089 19.5 0.3 10.8 9 2 1 10 10 10 7 Tetratricopeptide repeat TPR_6 PF13174.6 EAQ91409.1 - 4.1e-14 52.2 21.2 0.00041 20.8 0.0 10.4 11 0 0 11 11 9 3 Tetratricopeptide repeat TPR_7 PF13176.6 EAQ91409.1 - 8e-14 50.6 36.2 0.00024 20.9 0.1 11.5 13 0 0 13 13 10 4 Tetratricopeptide repeat TPR_17 PF13431.6 EAQ91409.1 - 2.4e-12 46.3 15.9 0.7 10.4 0.2 10.9 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_14 PF13428.6 EAQ91409.1 - 5.1e-12 45.6 41.0 0.0089 16.8 0.0 12.3 11 4 3 14 14 12 3 Tetratricopeptide repeat TPR_16 PF13432.6 EAQ91409.1 - 2.2e-09 37.8 39.2 0.00093 19.8 0.0 9.1 10 1 0 11 11 8 4 Tetratricopeptide repeat TPR_11 PF13414.6 EAQ91409.1 - 5.7e-05 22.7 37.3 0.039 13.7 0.0 10.8 13 0 0 13 13 13 4 TPR repeat TPR_10 PF13374.6 EAQ91409.1 - 0.00044 20.0 37.5 0.036 13.9 0.0 11.1 12 2 1 13 13 12 3 Tetratricopeptide repeat ANAPC3 PF12895.7 EAQ91409.1 - 0.00067 19.8 17.1 2.5 8.4 1.2 7.3 6 1 0 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.6 EAQ91409.1 - 0.026 14.6 1.3 4.7 7.4 0.2 4.6 4 0 0 4 4 3 0 Fis1 C-terminal tetratricopeptide repeat DUF627 PF04781.12 EAQ91409.1 - 0.38 10.8 5.2 1 9.4 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF627) TOM20_plant PF06552.12 EAQ91409.1 - 1.1 9.0 4.5 3.9 7.2 0.2 4.0 5 2 0 5 5 5 0 Plant specific mitochondrial import receptor subunit TOM20 TPR_3 PF07720.12 EAQ91409.1 - 2.5 8.2 9.9 36 4.5 0.1 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF4810 PF16068.5 EAQ91409.1 - 5 7.8 6.5 4.3 7.9 0.0 4.3 3 2 2 5 5 3 0 Domain of unknown function (DUF4810) PX PF00787.24 EAQ91411.1 - 1e-18 67.4 0.0 1.5e-17 63.6 0.0 2.6 3 0 0 3 3 3 1 PX domain Vps5 PF09325.10 EAQ91411.1 - 1.3e-06 28.2 0.2 1.3e-06 28.2 0.2 1.8 2 0 0 2 2 2 1 Vps5 C terminal like LST1 PF05083.13 EAQ91411.1 - 0.19 12.0 0.2 0.73 10.2 0.2 2.0 1 0 0 1 1 1 0 LST-1 protein mRNA_cap_enzyme PF01331.19 EAQ91412.1 - 3.6e-52 177.0 0.1 4.8e-52 176.6 0.1 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 EAQ91412.1 - 4.2e-32 111.0 0.0 8.6e-32 110.0 0.0 1.5 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.21 EAQ91412.1 - 1e-07 31.8 0.3 0.00039 20.1 0.0 2.3 1 1 1 2 2 2 2 ATP dependent DNA ligase domain RNA_ligase PF09414.10 EAQ91412.1 - 0.00047 20.5 0.0 0.0007 20.0 0.0 1.3 1 0 0 1 1 1 1 RNA ligase 2OG-FeII_Oxy_3 PF13640.6 EAQ91413.1 - 1.7e-05 25.6 1.0 8.2e-05 23.4 1.0 2.0 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 7tm_7 PF08395.12 EAQ91413.1 - 0.2 10.8 0.0 0.25 10.5 0.0 1.1 1 0 0 1 1 1 0 7tm Chemosensory receptor Fungal_trans PF04082.18 EAQ91414.1 - 8.5e-09 34.8 0.2 1.7e-08 33.8 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain FAD_binding_6 PF00970.24 EAQ91415.1 - 1.5e-29 102.3 0.0 2.3e-29 101.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 EAQ91415.1 - 3.8e-22 79.0 0.0 6.9e-22 78.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 EAQ91415.1 - 0.00041 20.5 0.0 0.018 15.2 0.0 2.1 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 EAQ91415.1 - 0.033 14.4 0.0 0.17 12.1 0.0 2.0 2 0 0 2 2 2 0 Siderophore-interacting FAD-binding domain TMEM208_SND2 PF05620.11 EAQ91416.1 - 6.8e-54 182.2 0.3 7.4e-54 182.0 0.3 1.0 1 0 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 DUF2955 PF11168.8 EAQ91416.1 - 0.0086 15.9 0.9 0.55 10.1 0.1 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2955) ANAPC3 PF12895.7 EAQ91417.1 - 2.7e-31 107.6 16.4 4.8e-24 84.4 0.1 4.6 4 0 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 EAQ91417.1 - 1.4e-29 100.7 17.2 8e-08 31.8 1.0 8.0 9 0 0 9 9 8 5 Tetratricopeptide repeat TPR_2 PF07719.17 EAQ91417.1 - 1e-28 97.1 17.8 1e-06 28.4 0.7 9.5 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_8 PF13181.6 EAQ91417.1 - 1e-18 65.9 10.6 0.0028 17.7 0.4 9.5 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_19 PF14559.6 EAQ91417.1 - 1.5e-18 67.0 14.5 1.9e-07 31.5 1.6 5.9 7 0 0 7 7 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 EAQ91417.1 - 1.6e-18 65.8 17.6 0.0008 20.0 0.0 9.5 4 1 6 10 10 10 3 Tetratricopeptide repeat TPR_12 PF13424.6 EAQ91417.1 - 9.2e-17 61.1 21.9 0.0017 18.6 0.2 8.3 5 3 2 7 7 7 5 Tetratricopeptide repeat TPR_16 PF13432.6 EAQ91417.1 - 3.2e-16 59.7 25.7 4.1e-08 33.7 1.2 7.9 7 1 1 8 8 8 4 Tetratricopeptide repeat TPR_11 PF13414.6 EAQ91417.1 - 3.3e-15 55.5 12.7 3e-07 30.0 1.7 7.2 7 2 2 9 9 9 3 TPR repeat TPR_7 PF13176.6 EAQ91417.1 - 2.3e-13 49.2 8.6 0.00063 19.6 0.0 7.0 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_17 PF13431.6 EAQ91417.1 - 5.8e-12 45.1 14.8 0.0088 16.4 0.3 8.0 10 0 0 10 10 8 3 Tetratricopeptide repeat TPR_6 PF13174.6 EAQ91417.1 - 1.9e-10 40.7 9.9 0.022 15.4 0.0 8.0 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_15 PF13429.6 EAQ91417.1 - 1.1e-05 24.9 7.5 0.012 14.8 0.1 4.5 3 1 3 6 6 6 4 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EAQ91417.1 - 5.1e-05 23.3 8.1 7.2 6.8 0.1 5.4 5 0 0 5 5 5 1 Fis1 C-terminal tetratricopeptide repeat TPR_9 PF13371.6 EAQ91417.1 - 0.00066 19.8 10.1 0.22 11.7 0.1 4.4 3 1 1 5 5 4 2 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 EAQ91417.1 - 0.0074 15.9 0.3 14 5.3 0.2 3.3 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_4 PF07721.14 EAQ91417.1 - 0.012 16.2 2.4 41 5.2 0.1 5.1 6 0 0 6 6 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 EAQ91417.1 - 0.12 12.3 16.9 5.4 7.0 0.0 6.5 7 1 1 8 8 8 0 Tetratricopeptide repeat DUF2225 PF09986.9 EAQ91417.1 - 0.14 11.9 0.3 4.8 6.8 0.2 2.8 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) MIT PF04212.18 EAQ91417.1 - 2 8.5 4.2 15 5.8 0.1 3.7 5 0 0 5 5 4 0 MIT (microtubule interacting and transport) domain Sedlin_N PF04628.13 EAQ91418.1 - 1.6e-15 57.4 0.0 1.9e-15 57.1 0.0 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region L31 PF09784.9 EAQ91419.1 - 5e-48 161.8 0.9 5.6e-48 161.6 0.9 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 MPS2 PF17060.5 EAQ91419.1 - 0.026 13.8 0.1 0.028 13.7 0.1 1.0 1 0 0 1 1 1 0 Monopolar spindle protein 2 Val_tRNA-synt_C PF10458.9 EAQ91419.1 - 0.077 13.3 0.7 4.6 7.6 0.2 2.8 2 1 0 3 3 3 0 Valyl tRNA synthetase tRNA binding arm RRM_1 PF00076.22 EAQ91420.1 - 7.6e-12 44.9 0.0 1.1e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup88 PF10168.9 EAQ91421.1 - 0.38 8.5 4.0 1.3 6.8 0.1 3.1 3 2 1 4 4 4 0 Nuclear pore component BNR_assoc_N PF14873.6 EAQ91422.1 - 0.17 11.6 0.8 0.28 10.8 0.8 1.2 1 0 0 1 1 1 0 N-terminal domain of BNR-repeat neuraminidase PI3_PI4_kinase PF00454.27 EAQ91424.1 - 2.4e-29 102.9 0.0 1e-28 100.9 0.0 2.0 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Pik1 PF11522.8 EAQ91424.1 - 4.8e-20 71.3 0.4 1.2e-19 70.0 0.1 1.9 2 0 0 2 2 2 1 Yeast phosphatidylinositol-4-OH kinase Pik1 DUF4135 PF13575.6 EAQ91424.1 - 0.085 12.2 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) AA_permease_2 PF13520.6 EAQ91425.1 - 2.4e-49 168.3 24.2 2e-29 102.7 11.5 2.1 1 1 1 2 2 2 2 Amino acid permease DUF3392 PF11872.8 EAQ91425.1 - 1.3 9.3 6.2 1.8 8.8 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3392) YwiC PF14256.6 EAQ91425.1 - 3.4 8.0 12.8 0.44 10.9 2.0 2.9 2 1 1 3 3 3 0 YwiC-like protein CBFD_NFYB_HMF PF00808.23 EAQ91427.1 - 4.2e-13 49.4 1.3 8.1e-13 48.5 1.3 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EAQ91427.1 - 0.02 15.3 0.4 0.032 14.6 0.4 1.3 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 TAFII28 PF04719.14 EAQ91427.1 - 0.058 13.5 0.8 0.12 12.4 0.8 1.5 1 0 0 1 1 1 0 hTAFII28-like protein conserved region DUF3098 PF11297.8 EAQ91428.1 - 0.014 15.0 0.0 0.024 14.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3098) Abhydrolase_3 PF07859.13 EAQ91429.1 - 9.2e-19 68.1 0.0 1.2e-18 67.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EAQ91429.1 - 4.2e-15 55.5 0.0 4.9e-15 55.3 0.0 1.0 1 0 0 1 1 1 1 Steryl acetyl hydrolase FGGY_C PF02782.16 EAQ91430.1 - 6.5e-28 97.8 0.0 1.3e-27 96.8 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 EAQ91430.1 - 6.6e-15 55.3 0.0 3.2e-06 26.9 0.0 2.5 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain Sad1_UNC PF07738.13 EAQ91431.1 - 1.6e-33 115.5 0.0 2.7e-33 114.8 0.0 1.4 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Muskelin_N PF06588.11 EAQ91431.1 - 0.14 12.0 0.1 0.29 11.0 0.1 1.4 1 0 0 1 1 1 0 Muskelin N-terminus TUDOR_5 PF18359.1 EAQ91431.1 - 0.19 11.4 0.1 0.49 10.1 0.1 1.7 1 0 0 1 1 1 0 Histone methyltransferase Tudor domain 1 RRM_2 PF04059.12 EAQ91432.1 - 1.8e-13 50.5 0.0 3.3e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif 2 Sec15 PF04091.12 EAQ91433.1 - 5.9e-97 324.9 2.4 5.9e-97 324.9 2.4 1.6 2 0 0 2 2 2 1 Exocyst complex subunit Sec15-like DUF2451 PF10474.9 EAQ91433.1 - 3.2e-06 27.1 0.5 1.1e-05 25.3 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function C-terminus (DUF2451) DUF4201 PF13870.6 EAQ91433.1 - 0.0037 17.0 2.8 0.0037 17.0 2.8 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF4201) DUF3510 PF12022.8 EAQ91433.1 - 0.0044 17.4 2.0 5.2 7.5 0.1 3.6 2 2 1 3 3 3 2 Domain of unknown function (DUF3510) Sec8_exocyst PF04048.14 EAQ91433.1 - 0.021 14.7 4.5 0.16 11.8 1.2 2.8 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain ApoLp-III PF07464.11 EAQ91433.1 - 0.13 12.3 3.5 0.28 11.3 1.5 2.6 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Vps54_N PF10475.9 EAQ91433.1 - 0.22 10.8 6.2 0.14 11.4 2.1 2.2 2 0 0 2 2 2 0 Vacuolar-sorting protein 54, of GARP complex DUF717 PF05338.12 EAQ91433.1 - 0.34 11.1 2.7 0.49 10.6 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF717) COG5 PF10392.9 EAQ91433.1 - 9 6.5 9.2 0.79 9.9 1.4 3.2 4 0 0 4 4 4 0 Golgi transport complex subunit 5 CBFD_NFYB_HMF PF00808.23 EAQ91434.1 - 3.1e-19 69.0 0.5 5.4e-19 68.2 0.5 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EAQ91434.1 - 6.7e-15 55.6 0.9 8.6e-15 55.3 0.2 1.5 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.10 EAQ91434.1 - 0.058 13.7 0.1 0.11 12.8 0.1 1.4 1 0 0 1 1 1 0 CENP-S associating Centromere protein X tRNA-synt_1b PF00579.25 EAQ91435.1 - 8e-58 196.1 0.3 7.5e-30 104.3 0.0 2.5 2 1 1 3 3 3 2 tRNA synthetases class I (W and Y) Fcf2 PF08698.11 EAQ91435.1 - 1.4e-30 105.6 0.1 3.9e-30 104.1 0.1 1.8 1 0 0 1 1 1 1 Fcf2 pre-rRNA processing Ribosomal_S10 PF00338.22 EAQ91435.1 - 5e-26 90.8 0.0 1.1e-25 89.7 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Get5_C PF18514.1 EAQ91436.1 - 0.07 12.9 0.0 0.22 11.3 0.0 1.9 1 0 0 1 1 1 0 Get5 C-terminal domain Creatinase_N_2 PF16189.5 EAQ91437.1 - 2.9e-51 173.8 0.1 7e-51 172.5 0.1 1.7 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 EAQ91437.1 - 4.6e-42 144.1 0.0 6.4e-42 143.6 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Peptidase_M24_C PF16188.5 EAQ91437.1 - 4.3e-22 77.9 0.1 2.4e-21 75.6 0.0 2.2 2 0 0 2 2 2 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 EAQ91437.1 - 1.8e-19 70.7 0.0 4.9e-15 56.3 0.0 2.6 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain TIP41 PF04176.13 EAQ91440.1 - 5.4e-63 211.6 0.0 6.7e-63 211.2 0.0 1.1 1 0 0 1 1 1 1 TIP41-like family Pkinase PF00069.25 EAQ91441.1 - 1.4e-71 240.9 0.0 1.7e-71 240.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ91441.1 - 1.3e-42 145.9 0.0 1.7e-42 145.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAQ91441.1 - 1.7e-08 34.1 0.0 2.1e-07 30.6 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 EAQ91441.1 - 0.0028 17.1 0.0 0.0044 16.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EAQ91441.1 - 0.022 14.7 0.0 0.032 14.2 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EAQ91441.1 - 0.033 13.1 0.0 0.044 12.7 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain FTA2 PF13095.6 EAQ91441.1 - 0.095 12.3 0.0 0.44 10.1 0.0 1.9 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 YrbL-PhoP_reg PF10707.9 EAQ91441.1 - 0.14 11.6 0.0 0.3 10.6 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL RIO1 PF01163.22 EAQ91441.1 - 0.15 11.6 0.0 0.5 9.9 0.0 1.7 1 1 1 2 2 2 0 RIO1 family Peptidase_M76 PF09768.9 EAQ91442.1 - 7e-36 123.6 1.5 2.1e-27 96.0 1.0 2.1 1 1 1 2 2 2 2 Peptidase M76 family AA_kinase PF00696.28 EAQ91443.1 - 1.7e-34 119.5 0.6 1.7e-34 119.5 0.6 1.7 2 0 0 2 2 2 1 Amino acid kinase family PUA PF01472.20 EAQ91443.1 - 4e-14 52.3 12.8 1.1e-13 51.0 10.3 2.6 2 1 0 2 2 2 1 PUA domain Ndc1_Nup PF09531.10 EAQ91443.1 - 0.61 8.7 4.2 0.84 8.2 4.2 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TFIIA PF03153.13 EAQ91443.1 - 0.62 10.0 8.7 0.88 9.5 8.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Suf PF05843.14 EAQ91443.1 - 3.8 7.4 7.0 5.2 7.0 7.0 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Hamartin PF04388.12 EAQ91443.1 - 4.9 5.7 14.1 6.6 5.3 14.1 1.1 1 0 0 1 1 1 0 Hamartin protein UPF0113 PF03657.13 EAQ91444.1 - 9.1e-24 83.5 0.0 1.3e-23 83.0 0.0 1.2 1 0 0 1 1 1 1 UPF0113 PUA domain UPF0113_N PF17833.1 EAQ91444.1 - 1e-23 83.7 0.0 1.4e-23 83.2 0.0 1.2 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain PUA PF01472.20 EAQ91444.1 - 0.13 12.3 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 PUA domain CDH-cyt PF16010.5 EAQ91445.1 - 2.3e-52 177.3 2.7 2.6e-47 160.8 0.6 3.0 2 1 1 3 3 3 2 Cytochrome domain of cellobiose dehydrogenase GMC_oxred_C PF05199.13 EAQ91445.1 - 8.4e-25 88.0 0.6 1.5e-24 87.2 0.6 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 EAQ91445.1 - 5.1e-24 85.2 0.0 1.4e-23 83.8 0.0 1.7 1 1 0 1 1 1 1 GMC oxidoreductase CBM_1 PF00734.18 EAQ91445.1 - 1.1e-10 41.3 10.4 2.4e-10 40.2 10.4 1.7 1 0 0 1 1 1 1 Fungal cellulose binding domain FAD_binding_2 PF00890.24 EAQ91445.1 - 1.6e-10 40.7 1.2 0.0002 20.6 0.6 2.1 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.7 EAQ91445.1 - 0.00013 21.4 0.2 0.012 15.0 0.7 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase DOMON PF03351.17 EAQ91445.1 - 0.00045 20.4 0.0 0.0017 18.6 0.0 1.9 1 0 0 1 1 1 1 DOMON domain Pyr_redox_2 PF07992.14 EAQ91445.1 - 0.0005 19.4 0.5 0.00095 18.5 0.3 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EAQ91445.1 - 0.00071 19.8 0.4 0.002 18.3 0.4 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EAQ91445.1 - 0.001 17.9 0.2 0.0017 17.1 0.2 1.3 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.24 EAQ91445.1 - 0.0013 18.4 4.8 0.012 15.3 4.9 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EAQ91445.1 - 0.0099 15.2 0.5 0.097 11.9 1.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EAQ91445.1 - 0.011 16.2 0.3 0.67 10.5 0.2 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EAQ91445.1 - 0.032 13.5 0.2 0.053 12.8 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 EAQ91445.1 - 0.033 13.4 1.0 0.055 12.7 0.2 1.8 2 0 0 2 2 2 0 Thi4 family GIDA PF01134.22 EAQ91445.1 - 0.19 10.8 0.6 0.36 9.9 0.6 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A Acetyltransf_7 PF13508.7 EAQ91446.1 - 0.0011 19.3 0.0 0.0025 18.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EAQ91446.1 - 0.002 18.4 0.0 0.0041 17.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 EAQ91446.1 - 0.02 15.0 0.0 0.041 14.0 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Arf PF00025.21 EAQ91447.1 - 9.7e-61 204.2 0.3 1.1e-60 204.1 0.3 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 EAQ91447.1 - 1.1e-08 34.6 0.4 0.00099 18.4 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 EAQ91447.1 - 1.5e-08 34.8 0.0 2.1e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EAQ91447.1 - 1.2e-07 31.4 0.0 1.5e-07 31.1 0.0 1.1 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 EAQ91447.1 - 5.2e-06 26.5 0.0 1.3e-05 25.3 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EAQ91447.1 - 3.2e-05 23.4 0.0 4.4e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EAQ91447.1 - 3.3e-05 23.4 0.0 3.9e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 EAQ91447.1 - 0.0047 16.5 0.0 0.15 11.6 0.0 2.3 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MeaB PF03308.16 EAQ91447.1 - 0.033 13.2 0.1 0.13 11.3 0.0 1.8 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NACHT PF05729.12 EAQ91447.1 - 0.042 13.8 0.1 0.45 10.4 0.0 2.0 2 0 0 2 2 2 0 NACHT domain Dynamin_N PF00350.23 EAQ91447.1 - 0.043 13.9 0.0 0.87 9.6 0.0 2.1 2 0 0 2 2 2 0 Dynamin family DUF4045 PF13254.6 EAQ91448.1 - 1.2e-83 282.1 41.8 9.3e-51 173.8 31.0 7.2 3 3 2 7 7 7 2 Domain of unknown function (DUF4045) Gelsolin PF00626.22 EAQ91448.1 - 2.9e-06 27.1 0.0 0.054 13.4 0.0 3.2 3 0 0 3 3 3 2 Gelsolin repeat Med10 PF09748.9 EAQ91449.1 - 4.9e-47 158.9 0.2 5.7e-47 158.6 0.2 1.0 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex Methyltransf_23 PF13489.6 EAQ91451.1 - 3.7e-36 124.4 0.0 4.9e-36 124.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAQ91451.1 - 0.00014 22.5 0.0 0.14 12.9 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 EAQ91451.1 - 0.00041 20.2 0.0 0.037 13.8 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EAQ91451.1 - 0.092 13.4 0.0 0.81 10.4 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.12 EAQ91451.1 - 0.12 13.2 0.0 0.83 10.4 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain bZIP_1 PF00170.21 EAQ91452.1 - 3.2e-05 23.9 7.2 3.2e-05 23.9 7.2 1.7 2 0 0 2 2 2 1 bZIP transcription factor ComFB PF10719.9 EAQ91452.1 - 0.17 12.0 1.5 0.31 11.2 1.5 1.4 1 0 0 1 1 1 0 Late competence development protein ComFB Nop53 PF07767.11 EAQ91452.1 - 0.35 10.2 8.0 0.5 9.7 8.0 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) GvpL_GvpF PF06386.11 EAQ91452.1 - 0.42 10.5 4.7 0.64 9.9 4.7 1.2 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF bZIP_2 PF07716.15 EAQ91452.1 - 0.47 10.6 8.4 1 9.5 8.4 1.6 1 0 0 1 1 1 0 Basic region leucine zipper Vir_act_alpha_C PF10400.9 EAQ91452.1 - 0.55 11.0 3.7 1.1 10.0 3.7 1.5 1 0 0 1 1 1 0 Virulence activator alpha C-term Stm1_N PF09598.10 EAQ91453.1 - 1.3e-14 54.8 0.3 1.3e-14 54.8 0.3 4.5 4 2 0 4 4 4 1 Stm1 HABP4_PAI-RBP1 PF04774.15 EAQ91453.1 - 7.9e-06 26.7 11.0 7.9e-06 26.7 11.0 1.9 2 0 0 2 2 2 1 Hyaluronan / mRNA binding family APC_u5 PF16630.5 EAQ91453.1 - 0.97 10.5 4.5 0.82 10.7 0.9 2.5 2 1 0 2 2 2 0 Unstructured region on APC between 1st and 2nd catenin-bdg motifs MFS_1 PF07690.16 EAQ91454.1 - 2.9e-17 62.6 33.2 4.8e-09 35.6 9.1 3.2 3 0 0 3 3 3 3 Major Facilitator Superfamily Mtc PF03820.17 EAQ91455.1 - 8.8e-107 356.8 0.1 1.2e-106 356.3 0.1 1.2 1 0 0 1 1 1 1 Tricarboxylate carrier Pkinase PF00069.25 EAQ91456.1 - 4.8e-41 140.9 0.0 2e-40 138.8 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ91456.1 - 2e-11 43.6 0.0 1.4e-10 40.9 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Lactamase_B_4 PF13691.6 EAQ91458.1 - 1.3e-26 92.1 0.0 2.7e-26 91.0 0.0 1.6 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B_2 PF12706.7 EAQ91458.1 - 1.7e-15 57.1 0.1 3e-15 56.3 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EAQ91458.1 - 3.1e-05 24.1 0.0 8.4e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily DEAD PF00270.29 EAQ91459.1 - 2.1e-46 157.9 0.1 2.1e-46 157.9 0.1 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF2183 PF09949.9 EAQ91459.1 - 1.3e-31 108.8 0.0 3.2e-31 107.6 0.0 1.7 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) Helicase_C PF00271.31 EAQ91459.1 - 1.5e-17 63.9 0.0 1e-16 61.2 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain LNS2 PF08235.13 EAQ91459.1 - 0.061 12.8 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 LNS2 (Lipin/Ned1/Smp2) Glyoxalase PF00903.25 EAQ91459.1 - 0.072 13.3 0.0 0.2 11.8 0.0 1.7 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily KIP1 PF07765.12 EAQ91459.1 - 0.85 9.8 4.7 3.7 7.7 4.7 2.1 1 0 0 1 1 1 0 KIP1-like protein SKG6 PF08693.10 EAQ91460.1 - 0.076 12.4 0.5 0.18 11.2 0.5 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Glyco_hydro_16 PF00722.21 EAQ91461.1 - 2.6e-05 23.7 0.0 5.4e-05 22.7 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 Flavin_Reduct PF01613.18 EAQ91462.1 - 3.7e-17 62.8 0.0 5.5e-17 62.2 0.0 1.2 1 0 0 1 1 1 1 Flavin reductase like domain PDEase_II PF02112.15 EAQ91463.1 - 3.6e-45 154.6 0.0 1.4e-21 77.0 0.0 2.1 2 0 0 2 2 2 2 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.7 EAQ91463.1 - 0.087 12.3 0.0 0.53 9.8 0.0 2.1 2 0 0 2 2 2 0 Beta-lactamase superfamily domain Herpes_UL35 PF04496.12 EAQ91464.1 - 0.034 14.4 0.2 0.12 12.6 0.2 1.9 1 0 0 1 1 1 0 Herpesvirus UL35 family Mgr1 PF08602.10 EAQ91464.1 - 0.15 10.8 0.2 0.28 10.0 0.2 1.3 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit zf-C2H2_2 PF12756.7 EAQ91465.1 - 1.1e-24 86.6 11.7 6.8e-23 80.9 6.0 2.3 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 EAQ91465.1 - 0.05 13.9 0.1 0.05 13.9 0.1 3.1 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 EAQ91465.1 - 0.18 12.7 10.1 14 6.9 0.1 3.9 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.26 EAQ91465.1 - 3.4 8.3 9.6 10 6.8 0.1 3.4 3 0 0 3 3 3 0 Zinc finger, C2H2 type AMP-binding PF00501.28 EAQ91466.1 - 6.2e-66 222.7 0.8 8.3e-27 93.8 0.8 4.3 3 1 0 3 3 3 3 AMP-binding enzyme DMAP_binding PF06464.11 EAQ91466.1 - 5.6e-10 40.0 0.0 1.2e-09 38.9 0.0 1.6 1 0 0 1 1 1 1 DMAP1-binding Domain GvpG PF05120.12 EAQ91466.1 - 0.024 14.7 0.5 0.052 13.6 0.5 1.5 1 0 0 1 1 1 0 Gas vesicle protein G PX PF00787.24 EAQ91469.1 - 2.1e-07 30.9 0.1 3.9e-07 30.1 0.1 1.4 1 0 0 1 1 1 1 PX domain Ribosomal_L12_N PF16320.5 EAQ91469.1 - 0.072 12.8 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L7/L12 dimerisation domain XhlA PF10779.9 EAQ91471.1 - 0.047 13.9 0.0 0.086 13.1 0.0 1.4 1 0 0 1 1 1 0 Haemolysin XhlA F-box-like PF12937.7 EAQ91473.1 - 0.0011 18.8 0.0 0.0037 17.1 0.0 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EAQ91473.1 - 0.023 14.6 0.1 0.084 12.8 0.1 2.0 1 0 0 1 1 1 0 F-box domain Pectate_lyase PF03211.13 EAQ91474.1 - 1.1e-83 279.8 5.4 1.3e-83 279.5 5.4 1.0 1 0 0 1 1 1 1 Pectate lyase DUF1996 PF09362.10 EAQ91475.1 - 2e-73 247.2 3.1 2.5e-73 246.9 3.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) EB1 PF03271.17 EAQ91476.1 - 2.6e-17 62.8 1.2 5.6e-17 61.7 1.2 1.6 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.31 EAQ91476.1 - 4.1e-07 30.2 0.3 7.7e-07 29.3 0.3 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain CH_2 PF06294.11 EAQ91476.1 - 0.094 12.8 0.2 0.15 12.2 0.2 1.3 1 0 0 1 1 1 0 CH-like domain in sperm protein KAR9 PF08580.10 EAQ91478.1 - 0.94 7.9 8.0 1 7.8 8.0 1.0 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Flavokinase PF01687.17 EAQ91479.1 - 3.6e-09 36.9 0.0 7.7e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 Riboflavin kinase Glyco_hydro_61 PF03443.14 EAQ91480.1 - 1.3e-61 208.1 0.1 2.3e-61 207.3 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.18 EAQ91480.1 - 1.7e-07 31.1 14.9 1.7e-07 31.1 14.9 3.5 2 2 0 2 2 2 1 Fungal cellulose binding domain NPCBM_assoc PF10633.9 EAQ91480.1 - 0.01 16.0 0.1 0.33 11.2 0.0 3.0 3 0 0 3 3 3 0 NPCBM-associated, NEW3 domain of alpha-galactosidase DUF1631 PF07793.11 EAQ91481.1 - 0.31 9.4 0.7 0.39 9.1 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) Man-6-P_recep PF02157.15 EAQ91482.1 - 1.1e-17 64.0 0.0 2.3e-16 59.6 0.0 2.1 2 0 0 2 2 2 1 Mannose-6-phosphate receptor ATG27 PF09451.10 EAQ91482.1 - 4.6e-15 56.2 0.1 1.9e-14 54.1 0.0 2.0 2 1 0 2 2 2 1 Autophagy-related protein 27 CIMR PF00878.18 EAQ91482.1 - 3.7e-07 30.3 0.2 0.00018 21.6 0.0 2.3 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat SDA1 PF05285.12 EAQ91482.1 - 0.0025 17.3 12.4 0.003 17.1 12.4 1.1 1 0 0 1 1 1 1 SDA1 VIR_N PF15912.5 EAQ91482.1 - 0.028 14.0 6.4 0.042 13.5 6.4 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal CDC45 PF02724.14 EAQ91482.1 - 0.16 10.3 13.9 0.21 9.9 13.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Zip PF02535.22 EAQ91482.1 - 0.18 11.0 0.1 0.26 10.4 0.1 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter DUF913 PF06025.12 EAQ91482.1 - 0.55 9.2 1.8 0.77 8.7 1.8 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Nop14 PF04147.12 EAQ91482.1 - 1 7.5 19.8 0.011 13.9 11.5 1.7 2 0 0 2 2 2 0 Nop14-like family CDC27 PF09507.10 EAQ91482.1 - 1.4 8.2 15.7 2.1 7.6 15.7 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 PPP4R2 PF09184.11 EAQ91482.1 - 6 6.4 17.2 8.5 5.9 17.2 1.2 1 0 0 1 1 1 0 PPP4R2 NOA36 PF06524.12 EAQ91482.1 - 7 5.9 19.9 11 5.2 19.9 1.3 1 0 0 1 1 1 0 NOA36 protein ERG4_ERG24 PF01222.17 EAQ91483.1 - 1.7e-172 574.1 1.1 1.9e-172 573.9 1.1 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 EAQ91483.1 - 1.5e-05 24.7 0.2 4.5e-05 23.1 0.2 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) LSM PF01423.22 EAQ91484.1 - 3.1e-11 42.8 0.0 4.3e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 LSM domain Glyco_hydro_3_C PF01915.22 EAQ91486.1 - 1.4e-51 175.3 0.0 2.7e-51 174.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EAQ91486.1 - 3.2e-38 131.9 0.0 5.6e-38 131.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EAQ91486.1 - 4.2e-16 58.8 0.0 1e-15 57.6 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF1823 PF08853.11 EAQ91486.1 - 0.019 15.1 0.0 8.3 6.6 0.0 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF1823) NCE101 PF11654.8 EAQ91488.1 - 0.23 11.2 1.7 0.32 10.7 0.1 2.0 2 0 0 2 2 2 0 Non-classical export protein 1 PGAP1 PF07819.13 EAQ91489.1 - 3.5e-07 30.2 0.0 4.6e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.14 EAQ91489.1 - 1.7e-06 27.7 0.0 2.4e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 EAQ91489.1 - 2.3e-05 25.1 0.2 2.5e-05 25.0 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_8 PF06259.12 EAQ91489.1 - 5e-05 23.0 0.0 7.7e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase LCAT PF02450.15 EAQ91489.1 - 0.0013 18.0 0.0 0.0017 17.6 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Cutinase PF01083.22 EAQ91489.1 - 0.0013 18.7 0.0 0.0018 18.3 0.0 1.2 1 0 0 1 1 1 1 Cutinase Hydrolase_4 PF12146.8 EAQ91489.1 - 0.0018 17.6 0.0 0.0026 17.0 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_9 PF10081.9 EAQ91489.1 - 0.0024 17.0 0.0 0.0036 16.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta-hydrolase family Palm_thioest PF02089.15 EAQ91489.1 - 0.014 15.2 0.0 0.017 15.0 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase DUF726 PF05277.12 EAQ91489.1 - 0.036 13.0 0.0 0.051 12.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF726) DUF3089 PF11288.8 EAQ91489.1 - 0.15 11.6 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) DUF3047 PF11249.8 EAQ91489.1 - 0.19 11.1 0.0 0.34 10.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3047) Abhydrolase_6 PF12697.7 EAQ91490.1 - 0.00046 20.9 0.4 0.00072 20.2 0.3 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.14 EAQ91490.1 - 0.00069 19.2 0.0 0.0016 18.0 0.0 1.6 1 1 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 EAQ91490.1 - 0.13 12.0 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein MCH PF02289.16 EAQ91490.1 - 0.13 11.5 0.0 0.17 11.1 0.0 1.1 1 0 0 1 1 1 0 Cyclohydrolase (MCH) NACHT PF05729.12 EAQ91491.1 - 1.8e-12 47.5 0.1 3.7e-12 46.5 0.1 1.5 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 EAQ91491.1 - 4.1e-06 27.1 0.1 1.7e-05 25.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EAQ91491.1 - 5.6e-05 23.6 0.1 0.00014 22.3 0.1 1.6 1 0 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.22 EAQ91491.1 - 0.0001 22.7 0.0 0.00032 21.1 0.0 1.9 1 0 0 1 1 1 1 RNA helicase ATPase_2 PF01637.18 EAQ91491.1 - 0.002 18.1 0.6 0.0061 16.5 0.0 1.9 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_5 PF07728.14 EAQ91491.1 - 0.0031 17.5 0.1 0.084 12.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA PF00004.29 EAQ91491.1 - 0.0064 16.9 0.0 0.015 15.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 EAQ91491.1 - 0.0069 16.9 0.0 0.017 15.6 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_25 PF13481.6 EAQ91491.1 - 0.0091 15.6 0.0 0.028 14.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 EAQ91491.1 - 0.0094 15.3 0.0 0.019 14.4 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI NB-ARC PF00931.22 EAQ91491.1 - 0.016 14.4 0.0 0.054 12.7 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain Hydrolase_4 PF12146.8 EAQ91491.1 - 0.024 13.9 0.0 0.045 13.0 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF676 PF05057.14 EAQ91491.1 - 0.027 14.0 0.0 0.11 12.0 0.0 2.1 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.7 EAQ91491.1 - 0.031 14.0 0.0 0.063 13.1 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family AAA_19 PF13245.6 EAQ91491.1 - 0.04 14.2 0.0 0.12 12.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF1690 PF07956.11 EAQ91491.1 - 0.13 12.7 1.2 0.33 11.4 1.2 1.7 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) ABC_tran_CTD PF16326.5 EAQ91492.1 - 0.00091 19.4 1.6 0.27 11.5 0.7 2.3 2 0 0 2 2 2 2 ABC transporter C-terminal domain eIF-4B PF06273.11 EAQ91492.1 - 0.0077 15.4 0.4 0.0086 15.2 0.4 1.1 1 0 0 1 1 1 1 Plant specific eukaryotic initiation factor 4B MIS13 PF08202.11 EAQ91492.1 - 0.017 14.4 1.0 0.021 14.1 1.0 1.1 1 0 0 1 1 1 0 Mis12-Mtw1 protein family DUF1732 PF08340.11 EAQ91492.1 - 0.053 13.5 0.1 0.11 12.5 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1732) FPP PF05911.11 EAQ91492.1 - 0.099 10.8 2.9 0.12 10.6 2.9 1.0 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil CENP-F_leu_zip PF10473.9 EAQ91492.1 - 0.099 12.7 4.8 0.15 12.1 4.7 1.3 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 BST2 PF16716.5 EAQ91492.1 - 0.16 12.5 4.8 2.8 8.6 1.4 2.7 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 ADIP PF11559.8 EAQ91492.1 - 0.25 11.4 2.7 0.63 10.1 0.9 1.9 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding SlyX PF04102.12 EAQ91492.1 - 0.27 11.9 2.9 7.6 7.2 0.9 2.6 2 1 0 2 2 2 0 SlyX CCDC-167 PF15188.6 EAQ91492.1 - 0.42 11.0 3.7 1.6 9.2 0.5 2.2 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 GrpE PF01025.19 EAQ91492.1 - 0.47 10.1 2.8 2.5 7.7 1.6 2.0 1 1 1 2 2 2 0 GrpE Tropomyosin_1 PF12718.7 EAQ91492.1 - 0.66 10.1 6.4 8.9 6.5 6.4 2.1 1 1 0 1 1 1 0 Tropomyosin like Lzipper-MIP1 PF14389.6 EAQ91492.1 - 0.78 10.1 6.5 4.6 7.6 1.5 3.1 1 1 1 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 Prefoldin_2 PF01920.20 EAQ91492.1 - 1.2 9.1 4.5 12 5.9 0.1 2.6 2 1 1 3 3 3 0 Prefoldin subunit DivIC PF04977.15 EAQ91492.1 - 2.3 8.0 7.8 18 5.2 1.3 3.0 2 1 1 3 3 3 0 Septum formation initiator GrpE PF01025.19 EAQ91493.1 - 0.0031 17.2 0.6 0.0037 16.9 0.6 1.1 1 0 0 1 1 1 1 GrpE DUF745 PF05335.13 EAQ91493.1 - 0.018 14.7 0.4 0.02 14.6 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF745) AMP-binding PF00501.28 EAQ91494.1 - 4.6e-71 239.6 0.0 5.9e-71 239.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EAQ91494.1 - 0.023 15.7 0.0 0.063 14.3 0.0 1.8 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Aminotran_3 PF00202.21 EAQ91495.1 - 3.5e-09 35.8 0.0 7.2e-09 34.8 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 EAQ91495.1 - 0.02 14.1 0.0 0.028 13.6 0.0 1.1 1 0 0 1 1 1 0 Aminotransferase class I and II SnoaL PF07366.12 EAQ91496.1 - 4.5e-05 23.3 0.1 0.00025 20.8 0.1 2.0 1 1 1 2 2 2 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 EAQ91496.1 - 8.9e-05 23.1 0.1 0.00039 21.0 0.0 2.1 2 0 0 2 2 2 1 SnoaL-like domain PIP5K PF01504.18 EAQ91498.1 - 1.8e-49 168.5 0.0 3.4e-49 167.5 0.0 1.5 2 0 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase PALP PF00291.25 EAQ91499.1 - 2.3e-65 220.9 0.3 3.3e-65 220.4 0.3 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.28 EAQ91499.1 - 3.1e-13 49.9 0.0 1.4e-07 31.8 0.0 3.5 3 0 0 3 3 3 2 CBS domain SRPRB PF09439.10 EAQ91500.1 - 3.2e-24 85.3 0.0 2.1e-15 56.6 0.0 3.2 2 1 1 3 3 3 3 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 EAQ91500.1 - 2.9e-05 24.5 0.6 7.1e-05 23.3 0.6 1.8 1 1 0 1 1 1 1 AAA ATPase domain Arf PF00025.21 EAQ91500.1 - 0.00022 20.8 0.0 0.032 13.7 0.0 2.5 2 1 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EAQ91500.1 - 0.0003 20.8 0.0 0.0014 18.7 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_23 PF13476.6 EAQ91500.1 - 0.0039 17.7 0.0 0.0054 17.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain TniB PF05621.11 EAQ91500.1 - 0.0056 16.1 0.0 0.0089 15.5 0.0 1.3 1 0 0 1 1 1 1 Bacterial TniB protein ABC_tran PF00005.27 EAQ91500.1 - 0.0065 17.0 0.0 0.0099 16.4 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_22 PF13401.6 EAQ91500.1 - 0.015 15.5 0.0 0.034 14.4 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAQ91500.1 - 0.017 15.5 0.0 3.3 8.1 0.1 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) SRP54 PF00448.22 EAQ91500.1 - 0.036 13.7 0.1 2.3 7.8 0.0 2.1 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain RsgA_GTPase PF03193.16 EAQ91500.1 - 0.04 13.8 0.2 0.19 11.6 0.2 2.0 2 1 0 2 2 2 0 RsgA GTPase NAD_binding_3 PF03447.16 EAQ91500.1 - 0.068 13.8 0.0 0.19 12.4 0.0 1.7 1 1 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain AAA_29 PF13555.6 EAQ91500.1 - 0.1 12.4 0.1 0.24 11.2 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.6 EAQ91500.1 - 0.14 11.9 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain Roc PF08477.13 EAQ91500.1 - 0.16 12.2 0.0 0.65 10.2 0.0 2.0 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EAQ91500.1 - 0.2 11.2 0.0 0.98 9.0 0.0 2.1 2 1 0 2 2 2 0 Ras family DHHC PF01529.20 EAQ91501.1 - 5.8e-36 123.6 11.1 5.8e-36 123.6 11.1 1.8 2 0 0 2 2 2 1 DHHC palmitoyltransferase Ank_2 PF12796.7 EAQ91501.1 - 6.6e-26 90.7 0.0 7.2e-13 48.9 0.0 2.7 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAQ91501.1 - 4e-23 81.2 0.1 3.1e-06 27.3 0.0 6.2 3 2 2 6 6 6 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAQ91501.1 - 1e-20 73.8 1.7 3.9e-07 30.5 0.4 4.2 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 EAQ91501.1 - 2.9e-20 71.7 0.5 0.00094 19.5 0.0 5.5 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 EAQ91501.1 - 1.9e-19 67.7 1.6 9.1e-06 25.7 0.0 5.8 5 0 0 5 5 5 4 Ankyrin repeat TssN PF17555.2 EAQ91501.1 - 0.062 12.7 1.3 0.12 11.8 1.3 1.4 1 0 0 1 1 1 0 Type VI secretion system, TssN PocR PF10114.9 EAQ91501.1 - 3.2 7.5 4.2 6.3 6.6 4.2 1.3 1 0 0 1 1 1 0 Sensory domain found in PocR DLH PF01738.18 EAQ91502.1 - 1.2e-30 106.7 0.1 1.7e-30 106.2 0.1 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 EAQ91502.1 - 0.043 13.3 0.1 0.76 9.2 0.0 2.1 1 1 1 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 EAQ91502.1 - 0.15 11.7 0.0 0.63 9.6 0.0 1.8 1 1 1 2 2 2 0 alpha/beta hydrolase fold CAP_N PF01213.19 EAQ91503.1 - 5.5 6.4 6.2 9.2 5.6 6.2 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal NmrA PF05368.13 EAQ91504.1 - 1.1e-29 103.6 0.0 1.5e-29 103.2 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EAQ91504.1 - 7.7e-13 48.7 0.0 1.3e-12 48.0 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EAQ91504.1 - 0.013 15.0 0.0 0.031 13.7 0.0 1.6 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Exo_endo_phos_2 PF14529.6 EAQ91505.1 - 4.2e-18 65.3 0.0 5.9e-17 61.6 0.0 2.3 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase RVT_1 PF00078.27 EAQ91505.1 - 6e-18 65.2 0.0 5.2e-17 62.1 0.0 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 EAQ91505.1 - 0.0013 18.7 1.7 0.0013 18.7 1.7 3.0 3 0 0 3 3 3 1 Zinc knuckle Exo_endo_phos PF03372.23 EAQ91505.1 - 0.058 12.9 0.0 0.086 12.3 0.0 1.3 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family Peptidase_M56 PF05569.11 EAQ91505.1 - 0.17 11.0 0.0 0.27 10.4 0.0 1.2 1 0 0 1 1 1 0 BlaR1 peptidase M56 MGC-24 PF05283.11 EAQ91505.1 - 2.7 8.4 6.9 18 5.7 1.8 2.6 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin zf-CCCH PF00642.24 EAQ91507.1 - 0.012 15.5 10.1 0.12 12.3 1.9 2.7 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 EAQ91507.1 - 0.02 14.7 5.2 0.02 14.7 5.2 3.2 2 1 0 2 2 2 0 CCCH-type zinc finger Acyl_transf_3 PF01757.22 EAQ91509.1 - 5.6e-38 130.9 34.5 7.1e-38 130.5 34.5 1.1 1 0 0 1 1 1 1 Acyltransferase family UDPG_MGDP_dh_N PF03721.14 EAQ91513.1 - 8.6e-42 142.8 0.2 1.8e-35 122.2 0.1 2.5 1 1 1 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.19 EAQ91513.1 - 2.4e-28 98.2 0.0 4.7e-28 97.2 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.15 EAQ91513.1 - 1.5e-22 80.0 0.0 7.4e-18 64.9 0.0 3.3 3 0 0 3 3 3 2 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain ADH_N PF08240.12 EAQ91513.1 - 0.08 12.8 0.6 7.8 6.4 0.0 2.6 3 0 0 3 3 3 0 Alcohol dehydrogenase GroES-like domain NAD_binding_2 PF03446.15 EAQ91513.1 - 0.12 12.5 0.2 0.52 10.5 0.2 2.1 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Glycos_transf_2 PF00535.26 EAQ91514.1 - 3.2e-24 85.6 0.0 4.8e-24 85.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 EAQ91514.1 - 1.9e-19 69.8 0.0 3.1e-19 69.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_trans_2_3 PF13632.6 EAQ91514.1 - 2.1e-16 60.4 5.9 2.1e-16 60.4 5.9 2.6 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EAQ91514.1 - 2.1e-15 57.2 0.1 3.2e-15 56.7 0.1 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_hydro_12 PF01670.16 EAQ91514.1 - 7.2e-11 42.5 0.7 3e-09 37.2 0.3 2.7 2 1 0 2 2 2 1 Glycosyl hydrolase family 12 Cellulose_synt PF03552.14 EAQ91514.1 - 0.00019 20.1 0.1 0.026 13.0 0.0 2.3 2 0 0 2 2 2 2 Cellulose synthase Glyco_hydro_7 PF00840.20 EAQ91517.1 - 1.7e-128 429.0 14.5 5.5e-127 424.1 14.5 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 7 Fer4_20 PF14691.6 EAQ91517.1 - 0.18 11.6 3.3 1.5 8.6 0.1 2.2 2 0 0 2 2 2 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Strep_SA_rep PF06696.11 EAQ91518.1 - 0.061 13.3 5.0 0.57 10.3 0.8 3.3 2 0 0 2 2 2 0 Streptococcal surface antigen repeat DUF1825 PF08855.10 EAQ91518.1 - 0.13 12.2 2.8 1.6 8.7 2.8 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF1825) DUF3012 PF11216.8 EAQ91518.1 - 0.17 11.9 0.0 0.36 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3012) CwsA PF10814.8 EAQ91518.1 - 1.4 9.1 10.5 0.86 9.8 1.5 2.6 1 1 2 3 3 3 0 Cell wall synthesis protein CwsA DivIC PF04977.15 EAQ91518.1 - 2.7 7.8 27.1 0.95 9.3 2.7 3.9 1 1 3 4 4 4 0 Septum formation initiator Lectin_N PF03954.14 EAQ91518.1 - 4.4 7.1 11.6 2.1 8.1 8.4 2.1 1 1 0 1 1 1 0 Hepatic lectin, N-terminal domain Spectrin PF00435.21 EAQ91518.1 - 6.9 7.2 20.4 43 4.7 11.4 2.7 1 1 1 2 2 2 0 Spectrin repeat OmdA PF13376.6 EAQ91519.1 - 1.1e-21 76.6 0.1 4e-21 74.8 0.1 2.0 1 0 0 1 1 1 1 Bacteriocin-protection, YdeI or OmpD-Associated Zn_clus PF00172.18 EAQ91519.1 - 5.1e-07 29.7 5.1 1.3e-06 28.4 5.1 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AGO_N PF18236.1 EAQ91519.1 - 0.11 12.8 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 Argonaute N domain Glyco_hydro_61 PF03443.14 EAQ91520.1 - 4.7e-11 43.0 0.1 5.7e-11 42.8 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Tyrosinase PF00264.20 EAQ91521.1 - 2e-41 142.7 4.9 3.3e-41 142.0 4.9 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase rve PF00665.26 EAQ91522.1 - 9.5e-10 38.7 0.0 2.5e-08 34.1 0.0 2.9 3 0 0 3 3 3 1 Integrase core domain gag_pre-integrs PF13976.6 EAQ91522.1 - 1.6e-05 24.7 0.4 4.3e-05 23.3 0.0 1.9 2 0 0 2 2 2 1 GAG-pre-integrase domain RVT_2 PF07727.14 EAQ91522.1 - 0.003 17.2 0.0 0.0061 16.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HEPN_AbiA_CTD PF18732.1 EAQ91522.1 - 0.12 12.3 0.3 20 5.1 0.0 2.4 2 0 0 2 2 2 0 HEPN like, Abia C-terminal domain MMM1 PF10296.9 EAQ91522.1 - 3.2 6.7 6.1 0.26 10.3 0.7 1.8 2 0 0 2 2 2 0 Maintenance of mitochondrial morphology protein 1 An_peroxidase PF03098.15 EAQ91524.1 - 8.5e-77 258.9 0.0 1.8e-53 182.0 0.0 2.0 1 1 1 2 2 2 2 Animal haem peroxidase DPPIV_N PF00930.21 EAQ91525.1 - 1.3e-106 356.4 4.0 1.5e-106 356.1 2.3 2.0 3 1 0 3 3 3 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 EAQ91525.1 - 1.5e-37 129.2 1.3 2.5e-37 128.4 1.3 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 EAQ91525.1 - 0.00016 21.4 2.4 0.00016 21.4 0.8 1.8 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) HTH_29 PF13551.6 EAQ91526.1 - 0.016 15.2 0.1 0.032 14.3 0.1 1.6 1 1 1 2 2 2 0 Winged helix-turn helix MFS_1 PF07690.16 EAQ91529.1 - 9e-29 100.5 26.4 2.5e-20 72.7 11.2 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EAQ91529.1 - 1.6e-08 33.9 6.2 1.6e-08 33.9 6.2 2.3 1 1 1 3 3 3 1 Sugar (and other) transporter Med15 PF09606.10 EAQ91534.1 - 0.0026 16.5 8.2 0.0035 16.1 8.2 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal DUF1631 PF07793.11 EAQ91534.1 - 0.0038 15.7 1.4 0.0046 15.5 1.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1631) DUF3391 PF11871.8 EAQ91534.1 - 0.1 13.1 0.1 0.16 12.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) TFIIA PF03153.13 EAQ91534.1 - 0.21 11.6 5.5 0.25 11.3 5.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CCDC53 PF10152.9 EAQ91534.1 - 0.64 10.4 2.4 0.94 9.9 2.4 1.3 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Neisseria_TspB PF05616.13 EAQ91534.1 - 3.1 6.2 7.1 4.5 5.7 7.1 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein PC4 PF02229.16 EAQ91535.1 - 0.002 17.7 0.0 0.0032 17.1 0.0 1.3 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) DNA_ligase_A_C PF04679.15 EAQ91535.1 - 0.14 12.7 0.0 0.17 12.5 0.0 1.2 1 0 0 1 1 1 0 ATP dependent DNA ligase C terminal region Glyco_transf_25 PF01755.17 EAQ91536.1 - 1e-10 41.8 0.0 6.6e-07 29.4 0.0 2.1 2 0 0 2 2 2 2 Glycosyltransferase family 25 (LPS biosynthesis protein) VSP PF03302.13 EAQ91537.1 - 0.078 11.8 0.0 0.096 11.5 0.0 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein SKG6 PF08693.10 EAQ91537.1 - 0.087 12.2 0.9 0.2 11.1 0.9 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Shisa PF13908.6 EAQ91537.1 - 0.72 10.1 2.0 1.4 9.2 0.0 1.9 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator DUF1996 PF09362.10 EAQ91538.1 - 2e-81 273.4 0.7 2.5e-81 273.1 0.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) CBM_1 PF00734.18 EAQ91538.1 - 0.0067 16.4 9.3 0.0067 16.4 9.3 2.5 2 0 0 2 2 2 1 Fungal cellulose binding domain AAA_22 PF13401.6 EAQ91539.1 - 0.00048 20.4 0.0 0.0016 18.7 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EAQ91539.1 - 0.00094 19.6 0.0 0.0032 17.9 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 EAQ91539.1 - 0.028 14.1 0.0 0.061 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EAQ91539.1 - 0.065 13.6 0.0 0.19 12.1 0.0 1.8 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.12 EAQ91539.1 - 0.13 12.1 0.5 0.75 9.7 0.5 2.2 1 1 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 EAQ91539.1 - 0.14 12.7 0.0 0.49 10.9 0.0 1.9 1 0 0 1 1 1 0 ABC transporter S1 PF00575.23 EAQ91540.1 - 7.1e-05 23.1 0.0 0.00014 22.2 0.0 1.4 1 0 0 1 1 1 1 S1 RNA binding domain WD40 PF00400.32 EAQ91542.1 - 3.2e-28 97.4 18.7 6.7e-06 26.8 0.0 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAQ91542.1 - 3.3e-08 33.7 0.1 0.0085 16.4 0.0 4.5 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain F-box-like PF12937.7 EAQ91542.1 - 8.4e-08 32.0 1.2 1.2e-07 31.6 0.2 1.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EAQ91542.1 - 8.6e-07 28.7 0.0 2.1e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.8 EAQ91542.1 - 2.4e-06 26.5 0.7 0.2 10.3 0.0 4.2 3 2 1 4 4 4 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 EAQ91542.1 - 0.0019 17.0 0.0 0.26 10.0 0.0 3.0 3 0 0 3 3 3 1 Nup133 N terminal like PQQ_2 PF13360.6 EAQ91542.1 - 0.017 14.7 0.2 0.62 9.6 0.1 2.4 1 1 1 2 2 2 0 PQQ-like domain DUF5046 PF16465.5 EAQ91542.1 - 0.067 12.6 0.1 18 4.7 0.1 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF5046) PALB2_WD40 PF16756.5 EAQ91542.1 - 0.071 12.0 0.2 19 4.0 0.0 3.3 1 1 1 3 3 3 0 Partner and localizer of BRCA2 WD40 domain WD40_like PF17005.5 EAQ91542.1 - 0.086 12.1 0.0 21 4.3 0.0 2.8 3 0 0 3 3 3 0 WD40-like domain Pectate_lyase_3 PF12708.7 EAQ91543.1 - 1.1e-96 322.8 13.6 7.6e-84 280.8 7.5 2.7 3 0 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 EAQ91543.1 - 2.9e-05 23.7 5.2 0.063 13.0 0.0 2.8 3 0 0 3 3 3 2 N terminal extension of bacteriophage endosialidase FTZ PF03867.14 EAQ91545.1 - 0.22 11.1 0.3 0.26 10.8 0.3 1.1 1 0 0 1 1 1 0 Fushi tarazu (FTZ), N-terminal region DUF1996 PF09362.10 EAQ91546.1 - 7.6e-82 274.8 2.2 9.4e-82 274.5 2.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Gal_mutarotas_2 PF13802.6 EAQ91546.1 - 0.097 13.0 0.2 0.26 11.6 0.2 1.7 1 0 0 1 1 1 0 Galactose mutarotase-like His_Phos_1 PF00300.22 EAQ91549.1 - 1.6e-09 37.7 1.0 1.8e-08 34.3 1.0 2.5 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Glyco_hydro_18 PF00704.28 EAQ91551.1 - 3.8e-72 243.7 0.3 5.8e-72 243.1 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 EAQ91551.1 - 2e-20 73.0 109.2 5.4e-12 46.0 17.4 5.5 5 0 0 5 5 5 4 Chitin recognition protein FSH1 PF03959.13 EAQ91553.1 - 0.027 14.1 0.0 0.027 14.1 0.0 1.1 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Lipase_GDSL_2 PF13472.6 EAQ91555.1 - 5.2e-15 56.3 1.3 6.4e-15 56.0 1.3 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EAQ91555.1 - 3.1e-08 33.8 0.9 4.6e-08 33.3 0.9 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase RE_AccI PF09545.10 EAQ91555.1 - 0.095 11.7 0.1 0.12 11.3 0.1 1.2 1 0 0 1 1 1 0 AccI restriction endonuclease AMP-binding PF00501.28 EAQ91556.1 - 1.1e-126 422.9 2.4 5.1e-63 213.1 0.0 3.2 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.20 EAQ91556.1 - 1.5e-53 182.1 0.0 1.3e-26 93.3 0.0 5.1 3 3 0 3 3 3 3 Condensation domain PP-binding PF00550.25 EAQ91556.1 - 1.7e-18 66.7 0.4 5.4e-11 42.7 0.1 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EAQ91556.1 - 9.7e-13 48.9 0.5 4.3e-07 30.8 0.0 3.2 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain MFS_1 PF07690.16 EAQ91557.1 - 1.3e-19 70.4 71.9 2.7e-18 66.0 42.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily CMD PF02627.20 EAQ91558.1 - 0.022 14.8 0.0 3.3 7.8 0.0 2.3 1 1 1 2 2 2 0 Carboxymuconolactone decarboxylase family ADH_zinc_N_2 PF13602.6 EAQ91559.1 - 0.00013 23.0 0.2 0.0016 19.5 0.0 2.2 1 1 1 2 2 2 1 Zinc-binding dehydrogenase DbpA PF03880.15 EAQ91559.1 - 0.024 14.6 0.0 0.046 13.7 0.0 1.4 1 0 0 1 1 1 0 DbpA RNA binding domain Amidase PF01425.21 EAQ91560.1 - 2.2e-98 330.2 0.0 3.6e-98 329.5 0.0 1.3 1 1 0 1 1 1 1 Amidase Methyltransf_3 PF01596.17 EAQ91561.1 - 7e-23 80.9 0.0 9.2e-23 80.5 0.0 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 EAQ91561.1 - 1.9e-13 51.3 0.0 3.4e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EAQ91561.1 - 4.6e-09 36.3 0.0 5.7e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 EAQ91561.1 - 1.3e-08 34.8 0.0 2.1e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAQ91561.1 - 1e-07 32.6 0.0 2.3e-07 31.4 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EAQ91561.1 - 6.1e-06 26.8 0.0 1.5e-05 25.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EAQ91561.1 - 8.7e-05 23.2 0.0 0.00018 22.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EAQ91561.1 - 0.00053 19.9 0.0 0.00083 19.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.10 EAQ91561.1 - 0.0038 16.8 0.0 0.0049 16.5 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Spermine_synth PF01564.17 EAQ91561.1 - 0.11 12.0 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Spermine/spermidine synthase domain F-box-like PF12937.7 EAQ91565.1 - 0.00093 19.0 0.0 0.0028 17.5 0.0 1.9 1 1 0 1 1 1 1 F-box-like LRR_4 PF12799.7 EAQ91565.1 - 0.07 13.6 1.0 46 4.6 0.0 4.1 3 2 2 5 5 5 0 Leucine Rich repeats (2 copies) MULE PF10551.9 EAQ91566.1 - 1.8e-09 37.9 0.1 4.1e-09 36.7 0.1 1.6 1 0 0 1 1 1 1 MULE transposase domain Tae4 PF14113.6 EAQ91566.1 - 0.0075 16.5 0.0 0.054 13.7 0.0 2.2 2 0 0 2 2 2 1 Type VI secretion system (T6SS), amidase effector protein 4 DUF664 PF04978.12 EAQ91566.1 - 0.016 15.6 0.0 0.13 12.7 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF664) Acyl_transf_3 PF01757.22 EAQ91568.1 - 7e-17 61.5 17.4 5.7e-16 58.5 17.5 2.3 1 1 0 1 1 1 1 Acyltransferase family FYDLN_acid PF09538.10 EAQ91569.1 - 0.15 12.8 2.2 0.26 12.0 2.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) RT_RNaseH PF17917.1 EAQ91570.1 - 4.5e-38 129.7 0.0 1e-37 128.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 EAQ91570.1 - 8.8e-33 112.3 0.0 2.3e-32 111.0 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 EAQ91570.1 - 4.6e-20 72.1 0.0 1.1e-19 70.9 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.24 EAQ91570.1 - 1.4e-11 44.1 0.7 4.8e-11 42.4 0.0 2.4 3 0 0 3 3 3 1 Chromo (CHRromatin Organisation MOdifier) domain Integrase_H2C2 PF17921.1 EAQ91570.1 - 1.3e-08 34.8 0.7 4.3e-08 33.2 0.0 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain SelB-wing_2 PF09106.11 EAQ91570.1 - 0.14 12.3 0.1 0.68 10.2 0.1 2.2 1 0 0 1 1 1 0 Elongation factor SelB, winged helix DUF4897 PF16238.5 EAQ91570.1 - 0.15 11.8 0.1 0.33 10.8 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4897) WD40 PF00400.32 EAQ91571.1 - 5.8e-43 144.0 17.4 8.9e-07 29.5 0.2 8.6 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAQ91571.1 - 5.3e-09 36.3 1.2 0.18 12.1 0.0 5.5 2 2 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain F-box-like PF12937.7 EAQ91571.1 - 5.4e-09 35.8 0.2 1.2e-08 34.7 0.2 1.7 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.8 EAQ91571.1 - 1.1e-08 34.2 1.3 0.073 11.7 0.0 4.1 3 1 1 4 4 4 3 Nucleoporin Nup120/160 F-box PF00646.33 EAQ91571.1 - 1.8e-06 27.7 0.0 6.2e-06 25.9 0.0 2.0 2 0 0 2 2 2 1 F-box domain F-box_4 PF15966.5 EAQ91571.1 - 0.00076 19.3 0.0 0.0034 17.2 0.0 2.2 1 0 0 1 1 1 1 F-box WD40_like PF17005.5 EAQ91571.1 - 0.12 11.7 0.1 2.2 7.5 0.2 2.6 2 1 0 2 2 2 0 WD40-like domain PALB2_WD40 PF16756.5 EAQ91571.1 - 0.45 9.4 7.1 17 4.2 0.0 4.6 4 2 1 6 6 6 0 Partner and localizer of BRCA2 WD40 domain Mito_carr PF00153.27 EAQ91572.1 - 1.3e-45 153.2 0.9 5.1e-20 71.2 0.1 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein p450 PF00067.22 EAQ91573.1 - 2.5e-67 227.6 0.0 3.2e-67 227.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Terpene_synth_C PF03936.16 EAQ91574.1 - 0.0006 19.2 0.0 0.0011 18.3 0.0 1.4 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain Wzy_C_2 PF11846.8 EAQ91578.1 - 0.24 11.3 1.2 0.42 10.5 1.2 1.4 1 0 0 1 1 1 0 Virulence factor membrane-bound polymerase, C-terminal NPV_P10 PF05531.12 EAQ91579.1 - 0.044 14.3 6.3 9.2 6.8 0.1 4.5 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF4795 PF16043.5 EAQ91579.1 - 1.1 8.8 9.9 0.28 10.8 4.7 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF4795) CdvA PF18822.1 EAQ91579.1 - 1.5 8.7 10.8 3 7.7 0.2 4.0 3 1 0 4 4 4 0 CdvA-like coiled-coil domain LrgB PF04172.16 EAQ91580.1 - 3.7e-15 56.0 12.2 1.6e-08 34.4 0.3 3.5 2 1 0 2 2 2 2 LrgB-like family Rotamase PF00639.21 EAQ91581.1 - 1.2e-22 80.7 0.0 1.7e-22 80.2 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 EAQ91581.1 - 3.1e-15 56.7 0.0 4.2e-15 56.3 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.26 EAQ91581.1 - 6.2e-08 32.6 1.5 1.4e-07 31.4 1.5 1.6 1 0 0 1 1 1 1 WW domain Rotamase_2 PF13145.6 EAQ91581.1 - 0.00031 21.6 0.0 0.00048 20.9 0.0 1.4 1 0 0 1 1 1 1 PPIC-type PPIASE domain Ago_PAZ PF18309.1 EAQ91581.1 - 0.1 13.2 0.1 0.19 12.4 0.1 1.5 1 1 0 1 1 1 0 Argonaute PAZ domain Ribosomal_L14 PF00238.19 EAQ91583.1 - 2.5e-43 147.1 3.8 2.9e-43 146.8 3.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e YopX PF09643.10 EAQ91583.1 - 0.04 14.0 0.0 0.044 13.8 0.0 1.1 1 0 0 1 1 1 0 YopX protein PAS_3 PF08447.12 EAQ91583.1 - 0.11 12.8 0.0 0.24 11.7 0.0 1.6 1 1 0 1 1 1 0 PAS fold SET PF00856.28 EAQ91584.1 - 1.7e-09 38.3 0.1 6e-08 33.3 0.0 2.5 1 1 0 2 2 2 1 SET domain Tmemb_55A PF09788.9 EAQ91584.1 - 0.061 12.4 0.3 0.13 11.4 0.3 1.5 1 0 0 1 1 1 0 Transmembrane protein 55A FAM76 PF16046.5 EAQ91584.1 - 0.43 9.9 7.4 0.086 12.2 1.2 2.2 2 0 0 2 2 2 0 FAM76 protein Velvet PF11754.8 EAQ91586.1 - 8.2e-08 32.5 0.0 9.2e-08 32.3 0.0 1.1 1 0 0 1 1 1 1 Velvet factor Acid_phosphat_B PF03767.14 EAQ91586.1 - 0.04 13.5 0.0 0.046 13.3 0.0 1.1 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) DUF4442 PF14539.6 EAQ91586.1 - 0.065 13.4 0.1 0.51 10.5 0.1 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4442) ACC_central PF08326.12 EAQ91587.1 - 9.4e-260 863.9 0.0 6e-226 752.1 0.0 2.1 1 1 1 2 2 2 2 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.22 EAQ91587.1 - 2.6e-41 141.8 0.0 4e-41 141.2 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 EAQ91587.1 - 9.8e-40 136.3 0.0 6e-19 68.4 0.0 2.4 1 1 1 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.19 EAQ91587.1 - 4.8e-23 81.3 0.0 2.5e-19 69.4 0.0 2.8 3 0 0 3 3 3 2 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 EAQ91587.1 - 1.6e-15 56.7 0.1 3.3e-15 55.7 0.1 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 EAQ91587.1 - 0.00046 19.8 0.0 0.00091 18.8 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 EAQ91587.1 - 0.0019 18.3 0.0 0.005 16.9 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 EAQ91587.1 - 0.022 14.6 0.1 0.12 12.2 0.0 2.2 2 0 0 2 2 2 0 Biotin-lipoyl like ATPgrasp_Ter PF15632.6 EAQ91587.1 - 0.086 12.6 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_carb_N PF00289.22 EAQ91587.1 - 0.12 13.0 0.0 0.27 11.8 0.0 1.6 1 0 0 1 1 1 0 Biotin carboxylase, N-terminal domain ATP-grasp PF02222.22 EAQ91587.1 - 0.14 11.7 0.0 0.59 9.7 0.0 2.0 2 0 0 2 2 2 0 ATP-grasp domain NUDE_C PF04880.13 EAQ91588.1 - 1.1e-41 143.2 14.3 1.1e-41 143.2 14.3 4.2 2 1 3 5 5 5 1 NUDE protein, C-terminal conserved region ZapB PF06005.12 EAQ91588.1 - 0.016 15.6 8.7 0.016 15.6 8.7 4.6 2 1 2 4 4 4 0 Cell division protein ZapB PSII_Pbs27 PF13326.6 EAQ91588.1 - 0.13 12.5 3.1 0.21 11.9 2.0 1.8 2 0 0 2 2 2 0 Photosystem II Pbs27 CENP-F_leu_zip PF10473.9 EAQ91588.1 - 0.14 12.2 31.7 0.087 12.8 22.1 3.7 2 1 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Chibby PF14645.6 EAQ91588.1 - 0.16 12.4 10.1 3.8 7.9 0.5 2.6 1 1 1 2 2 2 0 Chibby family DUF745 PF05335.13 EAQ91588.1 - 0.4 10.4 14.7 0.25 11.1 6.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Uso1_p115_C PF04871.13 EAQ91588.1 - 1.2 9.6 29.1 1.7 9.1 11.7 3.2 2 1 1 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region Fez1 PF06818.15 EAQ91588.1 - 1.3 9.5 28.6 0.29 11.6 10.7 3.1 2 1 1 3 3 3 0 Fez1 Atg14 PF10186.9 EAQ91588.1 - 4.2 6.4 23.6 0.18 10.8 9.8 3.3 2 1 1 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 Tho2 PF11262.8 EAQ91588.1 - 5.8 6.0 11.1 0.24 10.6 1.1 2.3 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 NUDIX PF00293.28 EAQ91589.1 - 4.1e-12 46.3 0.4 1e-11 45.0 0.2 1.7 2 0 0 2 2 2 1 NUDIX domain Glyco_hydro_61 PF03443.14 EAQ91590.1 - 7.5e-60 202.4 0.0 9.5e-60 202.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 AA_permease PF00324.21 EAQ91591.1 - 2.3e-86 290.3 40.0 6.4e-71 239.4 26.0 2.3 1 1 1 2 2 2 2 Amino acid permease AA_permease_2 PF13520.6 EAQ91591.1 - 1.4e-24 86.7 39.8 9.5e-22 77.4 23.0 2.1 1 1 1 2 2 2 2 Amino acid permease Homeobox_KN PF05920.11 EAQ91593.1 - 9e-17 60.7 0.2 2.9e-16 59.1 0.3 1.9 2 0 0 2 2 2 1 Homeobox KN domain Homeodomain PF00046.29 EAQ91593.1 - 4.5e-09 36.0 0.2 1e-08 34.9 0.2 1.6 1 0 0 1 1 1 1 Homeodomain zf-C2H2 PF00096.26 EAQ91593.1 - 0.00014 22.1 18.2 0.064 13.7 2.4 4.3 4 0 0 4 4 4 3 Zinc finger, C2H2 type HTH_Tnp_Tc5 PF03221.16 EAQ91593.1 - 0.00063 19.7 0.0 0.0016 18.4 0.0 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain zf-C2H2_4 PF13894.6 EAQ91593.1 - 0.0058 17.4 1.5 0.0058 17.4 1.5 4.6 4 0 0 4 4 4 2 C2H2-type zinc finger zf-met PF12874.7 EAQ91593.1 - 0.088 13.2 0.8 39 4.8 0.1 3.8 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_3rep PF18868.1 EAQ91593.1 - 0.16 12.6 1.5 2.1 9.1 0.1 2.4 2 0 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_2 PF12756.7 EAQ91593.1 - 1.6 9.1 4.1 38 4.7 0.4 2.8 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) TPMT PF05724.11 EAQ91594.1 - 3.4e-30 105.3 0.0 6.1e-30 104.5 0.0 1.4 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_25 PF13649.6 EAQ91594.1 - 8.9e-06 26.3 0.0 0.00036 21.2 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EAQ91594.1 - 1.9e-05 25.3 0.0 3.2e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EAQ91594.1 - 4.4e-05 23.4 0.0 7e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAQ91594.1 - 0.00026 20.8 0.0 0.011 15.6 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EAQ91594.1 - 0.00045 20.8 0.0 0.004 17.8 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Cys_Met_Meta_PP PF01053.20 EAQ91595.1 - 3.3e-20 72.0 0.0 4.5e-20 71.5 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DUF1308 PF07000.11 EAQ91595.1 - 0.0038 17.2 0.0 0.01 15.8 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1308) DUF5614 PF18474.1 EAQ91595.1 - 0.083 12.2 0.1 0.19 11.0 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5614) Spt20 PF12090.8 EAQ91596.1 - 0.013 15.2 3.8 0.014 15.0 3.8 1.2 1 0 0 1 1 1 0 Spt20 family RRN3 PF05327.11 EAQ91596.1 - 0.67 8.4 3.6 0.75 8.3 3.6 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 NmrA PF05368.13 EAQ91597.1 - 1.8e-43 148.8 0.0 2.7e-43 148.2 0.0 1.3 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EAQ91597.1 - 1.9e-19 70.2 0.0 3e-19 69.6 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EAQ91597.1 - 2.5e-07 30.4 0.1 9.5e-07 28.5 0.1 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EAQ91597.1 - 0.0048 15.9 0.0 0.0086 15.1 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.18 EAQ91597.1 - 0.011 16.0 0.0 0.027 14.7 0.0 1.6 1 1 0 1 1 1 0 TrkA-N domain Peripla_BP_6 PF13458.6 EAQ91597.1 - 0.051 13.2 0.9 5.1 6.7 0.1 2.3 2 0 0 2 2 2 0 Periplasmic binding protein F420_oxidored PF03807.17 EAQ91597.1 - 0.076 13.6 0.2 0.19 12.3 0.0 1.8 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent GDP_Man_Dehyd PF16363.5 EAQ91597.1 - 0.09 12.1 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Semialdhyde_dh PF01118.24 EAQ91597.1 - 0.15 12.5 0.1 0.58 10.6 0.1 2.0 3 0 0 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain ApbA PF02558.16 EAQ91597.1 - 0.16 11.6 0.1 0.84 9.3 0.1 2.0 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA HeLo PF14479.6 EAQ91598.1 - 4.9e-28 98.4 0.0 5.9e-28 98.1 0.0 1.1 1 0 0 1 1 1 1 Prion-inhibition and propagation Hamartin PF04388.12 EAQ91599.1 - 1.2 7.7 13.3 1.5 7.4 13.3 1.0 1 0 0 1 1 1 0 Hamartin protein DUF4292 PF14125.6 EAQ91600.1 - 0.18 11.4 0.2 0.32 10.7 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4292) Ank_2 PF12796.7 EAQ91601.1 - 1.2e-18 67.5 0.6 9.5e-11 42.1 0.2 5.2 3 1 1 5 5 5 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAQ91601.1 - 3.3e-15 54.7 2.1 0.05 14.2 0.0 6.8 7 0 0 7 7 5 4 Ankyrin repeat Ank_5 PF13857.6 EAQ91601.1 - 5.8e-12 45.6 0.7 0.0073 16.6 0.0 5.9 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAQ91601.1 - 1.2e-09 38.5 1.4 0.0025 18.3 0.1 4.7 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 EAQ91601.1 - 3.3e-09 36.8 3.8 0.00075 19.8 0.0 5.3 5 0 0 5 5 4 2 Ankyrin repeat AAA_16 PF13191.6 EAQ91601.1 - 8.5e-06 26.3 0.1 8.5e-06 26.3 0.1 3.1 3 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 EAQ91601.1 - 4.3e-05 23.8 0.1 0.00061 20.1 0.0 2.9 3 0 0 3 3 3 1 AAA domain NACHT PF05729.12 EAQ91601.1 - 0.00019 21.4 0.0 0.00067 19.6 0.0 2.0 1 1 0 1 1 1 1 NACHT domain AAA_19 PF13245.6 EAQ91601.1 - 0.0028 18.0 0.0 0.0077 16.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 EAQ91601.1 - 0.0032 16.8 0.1 0.0076 15.5 0.0 1.6 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) T2SSE PF00437.20 EAQ91601.1 - 0.08 12.0 0.0 0.45 9.5 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein Dimer_Tnp_hAT PF05699.14 EAQ91602.1 - 7.9e-06 25.6 0.0 0.00014 21.5 0.0 2.7 3 0 0 3 3 3 1 hAT family C-terminal dimerisation region PfkB PF00294.24 EAQ91603.1 - 1.1e-11 44.6 0.1 1.6e-11 44.1 0.1 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase APH PF01636.23 EAQ91604.1 - 0.00057 19.9 0.0 0.00099 19.1 0.0 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family RVT_1 PF00078.27 EAQ91605.1 - 1.4e-19 70.5 0.0 1.7e-17 63.7 0.0 2.3 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RecC_C PF17946.1 EAQ91605.1 - 0.045 13.5 3.6 1.2 8.8 0.2 2.7 2 0 0 2 2 2 0 RecC C-terminal domain Keratin_2_head PF16208.5 EAQ91606.1 - 8.9 6.4 27.9 15 5.7 27.9 1.3 1 0 0 1 1 1 0 Keratin type II head Myb_DNA-binding PF00249.31 EAQ91607.1 - 1.5e-07 31.4 0.4 4.1e-07 30.1 0.1 1.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAQ91607.1 - 0.00057 20.1 0.1 0.00096 19.4 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Abhydrolase_6 PF12697.7 EAQ91608.1 - 1.4e-14 55.3 13.0 2.8e-14 54.2 13.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EAQ91608.1 - 1.2e-13 51.3 0.1 1.3e-12 47.9 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EAQ91608.1 - 9.1e-12 44.7 0.2 1.4e-11 44.1 0.2 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EAQ91608.1 - 0.14 11.6 0.0 3.6 7.0 0.0 2.7 3 0 0 3 3 3 0 Prolyl oligopeptidase family HSP20 PF00011.21 EAQ91609.1 - 2.1e-17 63.1 0.1 1.1e-11 44.7 0.0 2.3 2 0 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 EAQ91609.1 - 6.8e-06 25.5 0.0 0.002 17.7 0.0 2.2 2 0 0 2 2 2 2 HSP20-like domain found in ArsA CPSF100_C PF13299.6 EAQ91609.1 - 1.2 9.3 4.0 1.9 8.6 4.0 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Peroxidase_2 PF01328.17 EAQ91611.1 - 1.5e-45 156.1 0.0 2e-45 155.6 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 Fungal_trans_2 PF11951.8 EAQ91612.1 - 2.5e-07 29.8 1.3 3.6e-07 29.3 1.3 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain PHO4 PF01384.20 EAQ91613.1 - 7e-80 268.6 14.8 9.1e-80 268.2 14.8 1.1 1 0 0 1 1 1 1 Phosphate transporter family Metallophos PF00149.28 EAQ91614.1 - 0.0048 17.4 0.7 0.0073 16.8 0.1 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EAQ91614.1 - 0.02 15.1 2.6 0.05 13.8 2.6 1.8 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Lipase_GDSL_2 PF13472.6 EAQ91615.1 - 9.1e-06 26.2 0.0 1.4e-05 25.6 0.0 1.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Homeobox_KN PF05920.11 EAQ91615.1 - 0.08 12.9 0.0 2 8.4 0.0 2.7 2 1 0 2 2 2 0 Homeobox KN domain Swi3 PF07962.12 EAQ91615.1 - 0.11 12.4 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Replication Fork Protection Component Swi3 DNA_pol_phi PF04931.13 EAQ91616.1 - 0.021 13.0 6.1 0.028 12.6 6.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi Sod_Fe_N PF00081.22 EAQ91616.1 - 0.046 14.2 0.2 0.092 13.2 0.2 1.6 1 0 0 1 1 1 0 Iron/manganese superoxide dismutases, alpha-hairpin domain Nop25 PF09805.9 EAQ91616.1 - 0.6 10.6 12.1 0.96 9.9 11.7 1.6 1 1 0 1 1 1 0 Nucleolar protein 12 (25kDa) Cu-oxidase_2 PF07731.14 EAQ91617.1 - 3e-40 137.2 12.8 9.1e-39 132.3 0.8 3.7 3 2 1 4 4 4 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 EAQ91617.1 - 2.4e-36 124.3 3.4 2.4e-36 124.3 3.4 3.3 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase PF00394.22 EAQ91617.1 - 1.8e-32 112.7 0.0 5.5e-32 111.1 0.0 1.8 1 0 0 1 1 1 1 Multicopper oxidase 3Beta_HSD PF01073.19 EAQ91618.1 - 2.2e-10 40.0 0.0 6.5e-10 38.5 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EAQ91618.1 - 1.2e-09 37.7 0.0 4.9e-06 25.9 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein Epimerase PF01370.21 EAQ91618.1 - 1.4e-09 37.8 0.0 4.7e-09 36.0 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EAQ91618.1 - 1.4e-06 28.3 0.0 2.4e-06 27.6 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 EAQ91618.1 - 5.8e-05 22.6 0.0 0.00031 20.3 0.0 1.8 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 EAQ91618.1 - 8.4e-05 22.2 0.0 0.00012 21.8 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.25 EAQ91618.1 - 0.082 12.3 0.0 1.2 8.6 0.0 2.2 2 0 0 2 2 2 0 short chain dehydrogenase LysM PF01476.20 EAQ91620.1 - 1.7e-21 76.0 1.8 0.0014 18.6 0.0 6.3 6 0 0 6 6 6 6 LysM domain LRV_FeS PF05484.11 EAQ91620.1 - 0.0082 16.1 0.0 30 4.7 0.0 3.7 3 0 0 3 3 3 1 LRV protein FeS4 cluster Como_LCP PF02247.16 EAQ91620.1 - 7.6 5.0 9.3 11 4.5 0.3 3.4 4 0 0 4 4 4 0 Large coat protein Fungal_lectin_2 PF18647.1 EAQ91621.1 - 7.8e-36 122.6 2.3 1.5e-35 121.7 2.3 1.5 1 0 0 1 1 1 1 Alpha-galactosyl-binding fungal lectin Lipase_GDSL_2 PF13472.6 EAQ91621.1 - 4.7e-13 49.9 0.3 3.9e-12 46.9 0.1 2.3 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EAQ91621.1 - 6.7e-08 32.7 0.0 1.4e-07 31.7 0.0 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Reprolysin_5 PF13688.6 EAQ91622.1 - 0.00082 19.6 0.1 0.0014 18.9 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12 Astacin PF01400.24 EAQ91622.1 - 0.0057 16.3 0.8 0.099 12.2 0.4 2.6 3 0 0 3 3 3 1 Astacin (Peptidase family M12A) Reprolysin_2 PF13574.6 EAQ91622.1 - 0.007 16.3 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 EAQ91622.1 - 0.0077 16.7 0.0 0.014 15.9 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 EAQ91622.1 - 0.021 14.5 0.2 0.14 11.8 0.1 2.2 3 0 0 3 3 3 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 EAQ91622.1 - 0.044 13.6 0.5 0.11 12.3 0.3 1.8 1 1 0 1 1 1 0 Matrixin Peptidase_M66 PF10462.9 EAQ91622.1 - 0.049 12.6 0.3 0.077 11.9 0.3 1.2 1 0 0 1 1 1 0 Peptidase M66 Glyco_hydro_18 PF00704.28 EAQ91623.1 - 1.4e-64 218.8 0.0 1.7e-64 218.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 EAQ91623.1 - 6.7e-09 36.1 30.2 1e-08 35.5 7.9 2.8 2 1 0 2 2 2 2 Chitin recognition protein RVT_2 PF07727.14 EAQ91626.1 - 4.8e-10 39.5 0.0 9.2e-10 38.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 EAQ91626.1 - 3.2e-08 33.8 0.1 1.4e-07 31.7 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.6 EAQ91626.1 - 1.4e-05 24.9 0.4 3.4e-05 23.6 0.4 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain Catalase PF00199.19 EAQ91629.1 - 8.1e-171 568.3 0.1 1e-170 568.0 0.1 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 EAQ91629.1 - 2.6e-22 78.8 0.1 5.4e-22 77.8 0.1 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive Catalase_C PF18011.1 EAQ91629.1 - 3.9e-11 42.8 1.1 1.4e-10 41.1 1.1 1.8 1 1 0 1 1 1 1 C-terminal domain found in long catalases DJ-1_PfpI PF01965.24 EAQ91629.1 - 6.9e-09 35.7 0.4 1.1e-08 35.1 0.4 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family TPR_12 PF13424.6 EAQ91630.1 - 0.034 14.4 2.4 0.43 10.9 1.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Ketoacyl-synt_C PF02801.22 EAQ91630.1 - 0.16 12.0 0.1 7.7 6.6 0.0 2.5 2 0 0 2 2 2 0 Beta-ketoacyl synthase, C-terminal domain AltA1 PF16541.5 EAQ91633.1 - 1.3e-21 77.6 2.5 3.7e-09 37.4 1.7 3.3 3 0 0 3 3 3 3 Alternaria alternata allergen 1 Tht1 PF04163.12 EAQ91634.1 - 2.2e-06 26.7 0.2 4.5e-06 25.7 0.2 1.4 1 1 0 1 1 1 1 Tht1-like nuclear fusion protein Focal_AT PF03623.13 EAQ91634.1 - 0.03 14.3 1.4 0.049 13.6 1.4 1.3 1 0 0 1 1 1 0 Focal adhesion targeting region SidE PF12252.8 EAQ91634.1 - 0.046 11.3 0.3 0.057 11.0 0.3 1.0 1 0 0 1 1 1 0 Dot/Icm substrate protein Glyco_tranf_2_3 PF13641.6 EAQ91635.1 - 2.9e-09 37.2 0.0 4e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 SNF2_N PF00176.23 EAQ91637.1 - 1.7e-10 40.2 0.0 0.00016 20.5 0.0 2.1 2 0 0 2 2 2 2 SNF2 family N-terminal domain ResIII PF04851.15 EAQ91637.1 - 0.021 14.9 0.0 0.85 9.6 0.0 2.7 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EAQ91637.1 - 0.1 13.0 0.0 0.19 12.1 0.0 1.4 1 0 0 1 1 1 0 Helicase conserved C-terminal domain Dimer_Tnp_hAT PF05699.14 EAQ91638.1 - 3.3e-05 23.6 0.0 0.00011 21.9 0.0 1.9 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region Cyclin_N PF00134.23 EAQ91639.1 - 4.9e-30 103.9 0.1 7.5e-30 103.3 0.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain DUF2157 PF09925.9 EAQ91639.1 - 0.036 13.9 0.1 0.062 13.1 0.1 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) Snapin_Pallidin PF14712.6 EAQ91640.1 - 0.23 11.9 1.4 0.5 10.8 0.2 2.1 2 0 0 2 2 2 0 Snapin/Pallidin FliD_N PF02465.18 EAQ91640.1 - 0.29 11.9 1.8 0.86 10.3 1.8 1.8 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus Tropomyosin PF00261.20 EAQ91640.1 - 0.74 9.1 9.6 0.14 11.5 5.0 1.9 2 0 0 2 2 2 0 Tropomyosin MULE PF10551.9 EAQ91641.1 - 2.2e-15 56.8 3.7 3.8e-14 52.9 0.3 2.9 1 1 1 2 2 2 1 MULE transposase domain DUF2992 PF11208.8 EAQ91641.1 - 0.0044 17.3 4.3 0.072 13.3 0.0 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF2992) FAR1 PF03101.15 EAQ91641.1 - 0.005 17.5 0.5 0.013 16.1 0.5 1.7 1 0 0 1 1 1 1 FAR1 DNA-binding domain DUF4125 PF13526.6 EAQ91641.1 - 0.16 11.6 1.5 0.36 10.4 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4125) RVT_1 PF00078.27 EAQ91642.1 - 1.3e-25 90.3 0.0 2.8e-25 89.2 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 EAQ91642.1 - 1.4e-15 57.2 0.0 3.6e-15 55.8 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 EAQ91642.1 - 4.3e-14 52.4 0.1 1.9e-13 50.3 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 EAQ91642.1 - 2.3e-13 50.4 1.7 4.6e-08 33.3 0.3 2.9 2 1 1 3 3 3 2 RNase H-like domain found in reverse transcriptase rve PF00665.26 EAQ91642.1 - 5e-12 46.1 0.1 1.3e-10 41.5 0.0 2.6 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.24 EAQ91642.1 - 0.00015 21.6 1.7 0.00032 20.6 1.7 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 EAQ91642.1 - 0.02 15.1 0.0 0.059 13.6 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger DUF3653 PF12375.8 EAQ91642.1 - 0.076 13.1 0.0 6.4 7.0 0.0 3.3 3 1 0 3 3 3 0 Phage protein Exo_endo_phos_2 PF14529.6 EAQ91643.1 - 2.3e-25 88.7 0.0 1e-24 86.6 0.0 2.2 3 0 0 3 3 3 1 Endonuclease-reverse transcriptase RVT_1 PF00078.27 EAQ91643.1 - 1.2e-21 77.2 0.0 6.3e-21 74.9 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 EAQ91643.1 - 0.00013 21.6 0.1 0.00027 20.5 0.1 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-CCHC PF00098.23 EAQ91643.1 - 0.0025 17.8 1.7 0.0025 17.8 1.7 2.8 2 0 0 2 2 1 1 Zinc knuckle SlyX PF04102.12 EAQ91643.1 - 0.0081 16.8 5.5 0.066 13.8 5.5 2.7 1 1 0 1 1 1 1 SlyX USP8_interact PF08941.10 EAQ91643.1 - 0.063 13.1 0.1 0.19 11.6 0.1 1.9 1 0 0 1 1 1 0 USP8 interacting HMMR_N PF15905.5 EAQ91643.1 - 0.081 12.4 0.5 0.14 11.6 0.5 1.2 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal CENP-F_leu_zip PF10473.9 EAQ91643.1 - 0.11 12.5 1.5 0.31 11.0 1.5 1.7 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CorA PF01544.18 EAQ91643.1 - 0.12 11.7 1.7 0.25 10.6 1.7 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein UPF0242 PF06785.11 EAQ91643.1 - 0.26 11.4 1.1 0.52 10.4 1.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus PKcGMP_CC PF16808.5 EAQ91643.1 - 0.29 11.0 2.5 0.38 10.7 0.5 2.2 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF3584 PF12128.8 EAQ91643.1 - 0.51 7.8 5.3 0.77 7.2 5.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) FAM76 PF16046.5 EAQ91643.1 - 5.7 6.2 14.8 0.15 11.4 0.1 2.4 2 0 0 2 2 2 0 FAM76 protein KELK PF15796.5 EAQ91643.1 - 5.8 7.4 7.5 15 6.1 3.3 2.7 2 0 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Exonuc_VII_L PF02601.15 EAQ91643.1 - 7.9 6.0 9.2 0.8 9.2 4.6 1.6 2 0 0 2 2 2 0 Exonuclease VII, large subunit FAR1 PF03101.15 EAQ91644.1 - 0.014 16.1 0.5 0.021 15.5 0.5 1.2 1 0 0 1 1 1 0 FAR1 DNA-binding domain Cellulase PF00150.18 EAQ91644.1 - 0.042 13.3 0.0 0.049 13.1 0.0 1.1 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) KTI12 PF08433.10 EAQ91644.1 - 0.046 13.2 0.0 0.056 12.9 0.0 1.1 1 0 0 1 1 1 0 Chromatin associated protein KTI12 HMG_box PF00505.19 EAQ91645.1 - 1.2e-23 83.3 0.3 4.2e-23 81.6 0.2 2.0 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EAQ91645.1 - 2.6e-06 27.9 0.0 5.7e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 HMG-box domain MAT1-1-2 PF17043.5 EAQ91646.1 - 1e-27 96.9 0.1 1.5e-27 96.3 0.1 1.3 1 0 0 1 1 1 1 Mating type protein 1-1-2 of unknown function SNF2_N PF00176.23 EAQ91647.1 - 1.2e-13 50.6 0.0 1.7e-06 27.0 0.0 2.1 2 0 0 2 2 2 2 SNF2 family N-terminal domain ResIII PF04851.15 EAQ91647.1 - 0.043 13.8 0.0 1.1 9.2 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EAQ91647.1 - 0.1 13.0 0.0 0.2 12.0 0.0 1.5 1 0 0 1 1 1 0 Helicase conserved C-terminal domain Dynamin_N PF00350.23 EAQ91648.1 - 4.1e-08 33.5 0.0 7.5e-08 32.6 0.0 1.5 2 0 0 2 2 2 1 Dynamin family Pkinase_fungal PF17667.1 EAQ91649.1 - 4.1e-06 25.8 0.1 7.9e-06 24.9 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase Pkinase PF00069.25 EAQ91649.1 - 6.3e-05 22.5 0.0 9.7e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain DUF2189 PF09955.9 EAQ91649.1 - 0.095 13.0 3.4 0.17 12.1 3.4 1.4 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2189) Helicase_C PF00271.31 EAQ91651.1 - 0.14 12.5 0.0 0.2 12.0 0.0 1.3 1 1 0 1 1 1 0 Helicase conserved C-terminal domain DUF3357 PF11837.8 EAQ91652.1 - 0.047 14.1 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) SSP160 PF06933.11 EAQ91652.1 - 0.11 10.7 5.4 0.15 10.3 5.4 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Herpes_capsid PF06112.11 EAQ91652.1 - 2 8.4 9.2 3.4 7.7 9.2 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Peptidase_S9 PF00326.21 EAQ91653.1 - 0.0003 20.4 0.0 0.00049 19.6 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 EAQ91653.1 - 0.0049 16.2 0.1 0.0067 15.7 0.1 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DLH PF01738.18 EAQ91653.1 - 0.0095 15.5 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family DUF829 PF05705.14 EAQ91653.1 - 0.022 14.6 0.0 0.028 14.3 0.0 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF829) FSH1 PF03959.13 EAQ91653.1 - 0.13 11.9 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase (FSH1) LIP PF03583.14 EAQ91653.1 - 0.16 11.2 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 Secretory lipase ketoacyl-synt PF00109.26 EAQ91654.1 - 6.7e-62 209.3 0.1 8.5e-61 205.7 0.0 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EAQ91654.1 - 3.6e-11 43.1 0.2 6.9e-11 42.2 0.2 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 EAQ91654.1 - 7.2e-07 28.8 0.1 1e-06 28.4 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.10 EAQ91654.1 - 0.00073 19.3 0.1 0.0017 18.2 0.1 1.6 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III p450 PF00067.22 EAQ91655.1 - 5e-18 65.1 0.0 9.1e-18 64.2 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 VQ PF05678.14 EAQ91656.1 - 0.07 12.6 1.2 0.14 11.7 0.1 2.2 2 0 0 2 2 2 0 VQ motif Herpes_LMP1 PF05297.11 EAQ91656.1 - 0.47 9.6 1.9 0.72 9.0 1.9 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) COesterase PF00135.28 EAQ91657.1 - 2.3e-93 313.8 0.0 3.6e-46 158.1 0.1 2.5 2 1 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 EAQ91657.1 - 4.2e-05 23.5 8.3 0.0099 15.8 0.4 2.8 2 1 0 3 3 3 2 alpha/beta hydrolase fold SQS_PSY PF00494.19 EAQ91657.1 - 0.074 12.5 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Squalene/phytoene synthase Zn_clus PF00172.18 EAQ91658.1 - 9.3e-05 22.5 7.1 0.00018 21.6 7.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EAQ91658.1 - 0.00022 20.4 0.2 0.00081 18.5 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain MFS_1 PF07690.16 EAQ91659.1 - 1.7e-21 76.5 48.8 2.4e-21 76.1 48.1 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily PsaA_PsaB PF00223.19 EAQ91659.1 - 0.026 12.8 3.2 0.036 12.3 3.2 1.2 1 0 0 1 1 1 0 Photosystem I psaA/psaB protein TPR_14 PF13428.6 EAQ91660.1 - 0.042 14.7 0.2 12 7.1 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat MFS_1 PF07690.16 EAQ91661.1 - 8.1e-31 107.2 32.1 8.1e-31 107.2 32.1 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 EAQ91661.1 - 1.3e-05 24.7 15.2 7.7e-05 22.1 15.2 2.1 1 1 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB zf-TRM13_CCCH PF11722.8 EAQ91662.1 - 0.0058 16.4 0.8 0.0058 16.4 0.8 4.9 6 0 0 6 6 6 2 CCCH zinc finger in TRM13 protein SET PF00856.28 EAQ91663.1 - 1.6e-07 31.9 0.0 3.6e-07 30.7 0.0 1.7 1 1 0 1 1 1 1 SET domain F-box-like PF12937.7 EAQ91664.1 - 0.0021 17.9 0.0 0.0053 16.6 0.0 1.7 1 0 0 1 1 1 1 F-box-like Peptidase_M24 PF00557.24 EAQ91665.1 - 3.2e-48 164.2 0.1 4.6e-48 163.7 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 EAQ91665.1 - 6.8e-24 84.0 0.0 1.2e-23 83.2 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain CHZ PF09649.10 EAQ91666.1 - 0.001 18.5 0.3 0.0023 17.3 0.3 1.6 1 0 0 1 1 1 1 Histone chaperone domain CHZ Cyclin PF08613.11 EAQ91667.1 - 4.8e-36 124.6 0.0 7.8e-36 123.9 0.0 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 EAQ91667.1 - 0.036 13.8 0.1 0.056 13.2 0.1 1.2 1 0 0 1 1 1 0 Cyclin, N-terminal domain zf-C2H2 PF00096.26 EAQ91668.1 - 3.4e-06 27.2 9.9 0.12 12.9 0.3 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_aberr PF17017.5 EAQ91668.1 - 0.0012 19.0 0.1 0.0024 18.0 0.1 1.4 1 0 0 1 1 1 1 Aberrant zinc-finger zf-H2C2_5 PF13909.6 EAQ91668.1 - 0.023 14.5 0.4 0.023 14.5 0.4 2.8 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 EAQ91668.1 - 0.048 14.5 9.7 3.8 8.6 0.6 3.8 3 1 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EAQ91668.1 - 8.1 7.1 11.3 27 5.4 0.2 3.7 3 0 0 3 3 3 0 Zinc-finger double domain OTT_1508_deam PF14441.6 EAQ91669.1 - 6.1e-17 61.4 0.0 1.7e-16 59.9 0.0 1.8 1 0 0 1 1 1 1 OTT_1508-like deaminase DUF2150 PF09920.9 EAQ91669.1 - 0.14 12.1 0.4 0.28 11.1 0.2 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2150) FtsJ PF01728.19 EAQ91670.1 - 5.3e-05 23.4 0.0 7.9e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase GPHH PF16905.5 EAQ91670.1 - 0.13 12.1 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 Voltage-dependent L-type calcium channel, IQ-associated TPP_enzyme_C PF02775.21 EAQ91671.1 - 2.4e-23 82.6 0.0 3.8e-23 82.0 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 EAQ91671.1 - 1.7e-13 50.5 0.0 7.8e-13 48.3 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_N PF02776.18 EAQ91671.1 - 3.8e-10 39.6 0.0 0.0019 17.8 0.0 3.1 3 0 0 3 3 3 2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain NTP_transf_3 PF12804.7 EAQ91671.1 - 0.0033 17.8 1.9 0.12 12.7 1.8 2.8 2 1 0 2 2 2 1 MobA-like NTP transferase domain Glyco_hydro_43 PF04616.14 EAQ91672.1 - 3.8e-63 213.5 4.1 4.7e-63 213.2 4.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 AbfB PF05270.13 EAQ91672.1 - 9.7e-10 38.6 0.1 4.5e-08 33.2 0.1 2.4 1 1 0 1 1 1 1 Alpha-L-arabinofuranosidase B (ABFB) domain Prok-E2_D PF14460.6 EAQ91672.1 - 0.12 12.1 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family D Glyco_hydro_62 PF03664.13 EAQ91673.1 - 6.5e-58 196.2 0.8 9.9e-58 195.6 0.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 MbtH PF03621.13 EAQ91673.1 - 0.077 12.5 0.2 0.19 11.2 0.2 1.6 1 0 0 1 1 1 0 MbtH-like protein FAM176 PF14851.6 EAQ91674.1 - 0.00089 18.9 0.0 0.0012 18.5 0.0 1.2 1 0 0 1 1 1 1 FAM176 family Herpes_gE PF02480.16 EAQ91674.1 - 0.0039 16.0 0.0 0.0049 15.7 0.0 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E PRIMA1 PF16101.5 EAQ91674.1 - 0.0045 17.0 8.6 0.0045 17.0 8.6 2.8 2 1 1 3 3 3 1 Proline-rich membrane anchor 1 LST1 PF05083.13 EAQ91674.1 - 0.0064 16.7 0.1 0.0092 16.2 0.1 1.3 1 0 0 1 1 1 1 LST-1 protein EphA2_TM PF14575.6 EAQ91674.1 - 0.028 15.3 0.0 0.038 14.9 0.0 1.2 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DEC-1_N PF04625.13 EAQ91674.1 - 0.28 10.1 10.2 0.37 9.8 10.2 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region CAP_N PF01213.19 EAQ91674.1 - 2.9 7.3 10.1 3.6 7.0 8.3 1.8 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.11 EAQ91674.1 - 4.3 7.3 6.3 1.4e+02 2.4 8.0 2.1 2 0 0 2 2 2 0 Mitochondrial fission regulator Anoctamin PF04547.12 EAQ91675.1 - 7.1e-72 242.7 0.0 9.3e-72 242.3 0.0 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Beta-lactamase PF00144.24 EAQ91675.1 - 1.4e-36 126.4 1.9 2.2e-36 125.7 1.4 1.6 2 0 0 2 2 2 1 Beta-lactamase RSN1_7TM PF02714.15 EAQ91677.1 - 9.9e-85 284.2 12.7 9.9e-85 284.2 12.7 1.6 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 EAQ91677.1 - 4.7e-42 143.4 3.0 1.5e-41 141.7 3.0 2.0 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 EAQ91677.1 - 1.1e-25 90.9 0.0 1.7e-25 90.3 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 EAQ91677.1 - 1.2e-18 67.1 0.1 6.8e-18 64.6 0.0 2.1 2 0 0 2 2 2 1 Extracellular tail, of 10TM putative phosphate transporter NACHT PF05729.12 EAQ91678.1 - 5.8e-05 23.1 0.0 0.00018 21.5 0.0 1.9 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 EAQ91678.1 - 0.001 19.3 0.0 0.0056 17.0 0.0 2.3 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 EAQ91678.1 - 0.094 13.1 0.0 0.21 12.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Hexose_dehydrat PF03559.14 EAQ91678.1 - 0.14 11.6 0.1 0.26 10.6 0.1 1.3 1 0 0 1 1 1 0 NDP-hexose 2,3-dehydratase THOC7 PF05615.13 EAQ91678.1 - 0.15 12.4 0.4 2.2 8.6 0.0 2.4 2 0 0 2 2 2 0 Tho complex subunit 7 CBM_21 PF03370.13 EAQ91681.1 - 2.3e-35 121.2 1.0 4e-35 120.4 1.0 1.4 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 EAQ91681.1 - 3e-11 43.7 0.5 6.4e-11 42.7 0.5 1.5 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) Trypsin PF00089.26 EAQ91683.1 - 6.1e-07 29.5 0.1 0.027 14.3 0.1 2.4 1 1 0 2 2 2 2 Trypsin Trypsin_2 PF13365.6 EAQ91683.1 - 0.0029 18.5 0.9 0.36 11.7 0.1 2.5 1 1 1 2 2 2 2 Trypsin-like peptidase domain Occludin_ELL PF07303.13 EAQ91683.1 - 0.042 14.6 0.3 0.1 13.3 0.3 1.6 1 0 0 1 1 1 0 Occludin homology domain MULE PF10551.9 EAQ91685.1 - 7.7e-24 83.9 0.0 1.4e-23 83.2 0.0 1.4 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.18 EAQ91685.1 - 0.00089 18.2 0.0 0.0015 17.5 0.0 1.2 1 0 0 1 1 1 1 Transposase, Mutator family Pex14_N PF04695.13 EAQ91686.1 - 0.16 12.7 10.1 0.24 12.0 10.1 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TFIIA PF03153.13 EAQ91686.1 - 0.3 11.0 9.0 0.34 10.9 9.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 EAQ91686.1 - 0.31 10.6 6.9 0.4 10.3 6.9 1.1 1 0 0 1 1 1 0 Spt20 family Suf PF05843.14 EAQ91686.1 - 1.1 9.1 4.6 1.4 8.8 4.6 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) ADH_zinc_N PF00107.26 EAQ91687.1 - 4.1e-18 65.6 0.0 6.2e-18 65.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EAQ91687.1 - 1.7e-15 58.3 0.0 2.5e-15 57.7 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Epimerase PF01370.21 EAQ91687.1 - 0.0055 16.2 0.0 0.0075 15.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family ELFV_dehydrog PF00208.21 EAQ91687.1 - 0.012 15.3 0.5 0.02 14.6 0.5 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase DapB_N PF01113.20 EAQ91687.1 - 0.02 15.0 0.1 0.03 14.5 0.1 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.24 EAQ91687.1 - 0.036 14.5 0.1 0.35 11.3 0.0 2.0 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain DFP PF04127.15 EAQ91687.1 - 0.041 13.7 0.0 0.063 13.1 0.0 1.2 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein APG17 PF04108.12 EAQ91688.1 - 1e-120 403.5 0.5 1.2e-120 403.3 0.5 1.0 1 0 0 1 1 1 1 Autophagy protein Apg17 YbjN PF10722.9 EAQ91688.1 - 0.034 14.2 0.4 0.084 12.9 0.4 1.7 1 0 0 1 1 1 0 Putative bacterial sensory transduction regulator DinB_2 PF12867.7 EAQ91688.1 - 0.054 14.0 1.4 0.5 10.9 0.1 2.8 1 1 1 2 2 2 0 DinB superfamily WXG100 PF06013.12 EAQ91688.1 - 0.11 12.7 4.2 15 5.9 0.1 4.5 5 0 0 5 5 5 0 Proteins of 100 residues with WXG Bap31_Bap29_C PF18035.1 EAQ91688.1 - 0.17 11.9 2.3 0.36 10.9 0.2 2.4 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain FH2 PF02181.23 EAQ91688.1 - 0.21 10.7 0.5 3.9 6.5 0.0 2.7 3 0 0 3 3 3 0 Formin Homology 2 Domain Chrome_Resist PF09828.9 EAQ91688.1 - 0.24 11.8 4.5 1.2 9.6 0.2 3.1 2 2 1 3 3 3 0 Chromate resistance exported protein RIO1 PF01163.22 EAQ91689.1 - 2.4e-68 229.4 0.0 6.8e-68 228.0 0.0 1.7 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 EAQ91689.1 - 0.0072 15.7 1.0 0.12 11.7 1.0 2.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EAQ91689.1 - 0.015 14.1 0.7 0.015 14.1 0.7 2.0 3 0 0 3 3 3 0 Fungal protein kinase Choline_kinase PF01633.20 EAQ91689.1 - 0.071 12.7 0.3 0.19 11.3 0.3 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.23 EAQ91689.1 - 0.15 11.9 4.4 3.9 7.3 0.1 2.6 2 1 1 3 3 3 0 Phosphotransferase enzyme family DUF3464 PF11947.8 EAQ91689.1 - 1.4 8.7 7.0 0.17 11.6 1.4 2.2 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 Ribonuc_L-PSP PF01042.21 EAQ91690.1 - 8.4e-19 67.8 0.0 1.1e-18 67.4 0.0 1.2 1 0 0 1 1 1 1 Endoribonuclease L-PSP MFS_1 PF07690.16 EAQ91691.1 - 2.6e-51 174.6 33.9 3.8e-51 174.1 33.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EAQ91691.1 - 2.7e-13 49.6 12.7 4.2e-13 49.0 12.7 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter Med22 PF06179.12 EAQ91691.1 - 6.9e-13 48.7 0.1 1.3e-12 47.8 0.1 1.5 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex MFS_4 PF06779.14 EAQ91691.1 - 0.00011 21.6 2.4 0.00023 20.6 2.4 1.6 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB TRI12 PF06609.13 EAQ91691.1 - 0.00018 20.1 2.1 0.00028 19.4 2.1 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 EAQ91691.1 - 0.0021 16.4 3.4 0.0021 16.4 3.4 1.7 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family DUF21 PF01595.20 EAQ91691.1 - 0.39 10.4 2.9 9.4 5.9 0.2 2.4 2 0 0 2 2 2 0 Cyclin M transmembrane N-terminal domain PseudoU_synth_1 PF01416.20 EAQ91692.1 - 2.3e-10 40.9 0.0 1.5e-08 35.1 0.0 2.5 2 0 0 2 2 2 1 tRNA pseudouridine synthase DUF2344 PF10105.9 EAQ91692.1 - 0.065 13.1 0.1 0.96 9.3 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2344) SKG6 PF08693.10 EAQ91693.1 - 0.00038 19.8 0.0 0.00038 19.8 0.0 1.8 2 0 0 2 2 2 1 Transmembrane alpha-helix domain TMEM154 PF15102.6 EAQ91693.1 - 0.0012 18.7 0.0 0.0019 18.1 0.0 1.3 1 0 0 1 1 1 1 TMEM154 protein family Mid2 PF04478.12 EAQ91693.1 - 0.053 13.3 0.0 0.089 12.6 0.0 1.3 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor DUF515 PF04415.12 EAQ91693.1 - 0.55 8.6 6.6 0.74 8.1 6.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Presenilin PF01080.17 EAQ91694.1 - 0.00011 21.1 0.8 0.00015 20.7 0.8 1.1 1 0 0 1 1 1 1 Presenilin Apt1 PF10351.9 EAQ91694.1 - 0.057 12.3 6.2 0.062 12.1 6.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Med13_C PF06333.12 EAQ91694.1 - 0.091 12.0 8.6 0.13 11.5 8.6 1.2 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain Ndc1_Nup PF09531.10 EAQ91694.1 - 0.11 11.1 4.2 0.14 10.8 4.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SPX PF03105.19 EAQ91694.1 - 0.32 10.9 11.2 0.38 10.6 11.2 1.1 1 0 0 1 1 1 0 SPX domain GREB1 PF15782.5 EAQ91694.1 - 1.8 5.6 3.9 2.2 5.3 3.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer NPR3 PF03666.13 EAQ91694.1 - 9.9 4.8 6.8 13 4.5 6.8 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 tRNA-synt_1c PF00749.21 EAQ91695.1 - 1.9e-76 256.9 0.0 2.4e-76 256.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1e PF01406.19 EAQ91695.1 - 0.038 13.3 0.1 0.083 12.2 0.1 1.5 1 1 1 2 2 2 0 tRNA synthetases class I (C) catalytic domain Methyltransf_25 PF13649.6 EAQ91696.1 - 1.7e-05 25.4 0.0 4.4e-05 24.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 EAQ91696.1 - 0.0018 19.2 0.0 0.013 16.5 0.0 2.2 1 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAQ91696.1 - 0.0019 18.0 0.0 0.003 17.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EAQ91696.1 - 0.0032 18.2 0.0 0.01 16.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EAQ91696.1 - 0.0039 17.0 0.0 0.007 16.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 EAQ91696.1 - 0.033 13.8 0.0 0.28 10.7 0.0 2.2 3 0 0 3 3 3 0 Methionine biosynthesis protein MetW ADH_zinc_N PF00107.26 EAQ91698.1 - 3.4e-08 33.5 0.5 7.1e-08 32.5 0.5 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EAQ91698.1 - 1.8e-06 27.8 0.0 2.9e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EAQ91698.1 - 0.0057 17.7 0.1 0.011 16.8 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 EAQ91698.1 - 0.012 15.5 0.0 0.031 14.2 0.0 1.6 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase adh_short_C2 PF13561.6 EAQ91698.1 - 0.016 14.8 0.8 0.027 14.0 0.8 1.4 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase MRP-S27 PF10037.9 EAQ91698.1 - 0.33 9.8 0.0 0.46 9.3 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 DUF4360 PF14273.6 EAQ91699.1 - 4.3e-47 160.3 0.5 4.9e-47 160.1 0.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) SRP-alpha_N PF04086.13 EAQ91700.1 - 1.4 8.8 7.5 2.4 8.0 7.5 1.4 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal PEP_mutase PF13714.6 EAQ91701.1 - 2.7e-44 151.4 0.1 4.2e-44 150.8 0.1 1.2 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase UvrD_C_2 PF13538.6 EAQ91701.1 - 0.047 13.5 0.0 0.15 11.9 0.0 1.9 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain AP_endonuc_2 PF01261.24 EAQ91701.1 - 0.06 12.8 0.2 0.5 9.8 0.0 2.5 3 1 0 3 3 3 0 Xylose isomerase-like TIM barrel PIF1 PF05970.14 EAQ91701.1 - 0.13 11.4 0.1 0.23 10.6 0.1 1.3 1 0 0 1 1 1 0 PIF1-like helicase GMC_oxred_N PF00732.19 EAQ91702.1 - 6.9e-39 134.0 0.2 5.2e-36 124.5 0.4 2.2 2 0 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.13 EAQ91702.1 - 3.3e-24 86.0 0.0 6.3e-24 85.1 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 EAQ91702.1 - 4.4e-07 29.4 1.3 5.2e-05 22.6 0.2 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EAQ91702.1 - 3.7e-05 23.9 0.1 3.7e-05 23.9 0.1 2.6 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EAQ91702.1 - 0.00015 21.0 0.9 0.00033 19.9 0.4 1.8 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 EAQ91702.1 - 0.00075 19.2 0.1 0.0082 15.8 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EAQ91702.1 - 0.0023 16.7 0.0 0.0041 15.9 0.0 1.4 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.7 EAQ91702.1 - 0.0027 17.1 0.1 0.0055 16.1 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EAQ91702.1 - 0.022 14.0 0.2 0.022 14.0 0.2 1.6 2 0 0 2 2 1 0 FAD binding domain Lycopene_cycl PF05834.12 EAQ91702.1 - 0.025 13.6 0.0 0.047 12.7 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 EAQ91702.1 - 0.026 13.8 4.0 0.032 13.5 0.1 2.4 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EAQ91702.1 - 0.059 12.4 0.2 0.11 11.6 0.2 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A RdRP PF05183.12 EAQ91703.1 - 7.5e-135 450.8 0.0 9.9e-135 450.4 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase Fungal_trans PF04082.18 EAQ91704.1 - 7.7e-09 35.0 1.5 1e-08 34.6 0.3 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain HMG_box PF00505.19 EAQ91704.1 - 9.2e-08 32.4 0.0 2e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box Peptidase_M14 PF00246.24 EAQ91706.1 - 2.1e-42 145.9 0.0 2.5e-42 145.7 0.0 1.0 1 0 0 1 1 1 1 Zinc carboxypeptidase C2 PF00168.30 EAQ91707.1 - 2.3e-19 69.6 0.0 1.6e-12 47.6 0.0 2.3 2 0 0 2 2 2 2 C2 domain SMP_LBD PF17047.5 EAQ91707.1 - 1.1e-13 51.0 0.5 5.4e-06 26.0 0.0 2.3 1 1 1 2 2 2 2 Synaptotagmin-like mitochondrial-lipid-binding domain DIOX_N PF14226.6 EAQ91708.1 - 0.00025 21.8 0.0 0.0006 20.5 0.0 1.6 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EAQ91708.1 - 0.011 16.2 0.0 0.018 15.5 0.0 1.4 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Peptidase_C2 PF00648.21 EAQ91710.1 - 1.1e-59 202.0 0.2 2.9e-58 197.3 0.2 2.2 1 1 0 1 1 1 1 Calpain family cysteine protease RR_TM4-6 PF06459.12 EAQ91711.1 - 0.32 10.8 9.2 0.38 10.5 9.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Coilin_N PF15862.5 EAQ91711.1 - 0.4 10.5 9.4 0.6 9.9 9.4 1.3 1 0 0 1 1 1 0 Coilin N-terminus NPR3 PF03666.13 EAQ91711.1 - 1.2 7.8 8.2 1.6 7.4 8.2 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Nop14 PF04147.12 EAQ91711.1 - 4.7 5.3 17.9 5.5 5.1 17.9 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 EAQ91711.1 - 8.7 4.5 11.7 10 4.2 11.7 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF202 PF02656.15 EAQ91712.1 - 6.2 7.3 7.2 28 5.2 7.2 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF202) Asp PF00026.23 EAQ91713.1 - 7.7e-41 140.5 0.7 1.1e-40 140.1 0.7 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EAQ91713.1 - 3.3e-05 24.2 0.5 8e-05 22.9 0.0 1.9 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Serglycin PF04360.12 EAQ91713.1 - 0.009 16.0 1.8 0.022 14.7 1.8 1.6 1 0 0 1 1 1 1 Serglycin Cofilin_ADF PF00241.20 EAQ91714.1 - 2.4e-36 124.2 0.0 1.8e-21 76.2 0.0 2.1 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein GATase PF00117.28 EAQ91715.1 - 3.4e-05 23.7 0.0 5.5e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Ribosomal_S7e PF01251.18 EAQ91716.1 - 4.8e-80 267.7 0.1 5.6e-80 267.5 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e ADH_N PF08240.12 EAQ91717.1 - 5.1e-26 90.7 3.5 8e-26 90.1 3.5 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EAQ91717.1 - 9.9e-13 48.2 0.4 2.8e-12 46.8 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 EAQ91717.1 - 2.1e-05 23.9 0.2 3.8e-05 23.1 0.2 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 EAQ91717.1 - 0.02 14.2 0.0 0.044 13.1 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Gp_dh_N PF00044.24 EAQ91717.1 - 0.031 14.6 0.1 8.2 6.8 0.0 2.5 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Dynactin_p62 PF05502.13 EAQ91718.1 - 8.8e-216 717.3 0.0 1.1e-215 717.0 0.0 1.0 1 0 0 1 1 1 1 Dynactin p62 family zf-FPG_IleRS PF06827.14 EAQ91718.1 - 2.2 8.2 12.4 3.2 7.7 0.5 3.9 4 0 0 4 4 4 0 Zinc finger found in FPG and IleRS DUF4519 PF15012.6 EAQ91718.1 - 2.4 8.4 5.0 0.49 10.6 0.9 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) DUF2653 PF10850.8 EAQ91719.1 - 0.17 12.1 0.0 0.3 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2653) BolA PF01722.18 EAQ91721.1 - 1e-08 35.3 0.0 2.3e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 BolA-like protein Peptidase_S8 PF00082.22 EAQ91723.1 - 1.4e-42 146.0 0.0 3e-42 144.9 0.0 1.5 1 1 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 EAQ91723.1 - 3e-22 79.5 0.2 6.3e-22 78.4 0.2 1.6 1 0 0 1 1 1 1 Fn3-like domain FlgD_ig PF13860.6 EAQ91723.1 - 4.8e-07 29.6 0.1 1.4e-06 28.1 0.1 1.8 1 0 0 1 1 1 1 FlgD Ig-like domain PA PF02225.22 EAQ91723.1 - 4.5e-06 26.6 2.5 6.1e-06 26.2 0.1 2.5 2 0 0 2 2 2 1 PA domain Apocytochr_F_C PF01333.19 EAQ91723.1 - 0.094 12.8 0.0 0.23 11.5 0.0 1.6 1 0 0 1 1 1 0 Apocytochrome F, C-terminal DUF2206 PF09971.9 EAQ91725.1 - 0.19 10.5 0.0 0.21 10.3 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2206) UCR_Fe-S_N PF10399.9 EAQ91726.1 - 4.2 6.8 8.1 11 5.5 8.1 1.6 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Glyco_hydro_79C PF16862.5 EAQ91727.1 - 2e-21 76.8 1.6 4.1e-21 75.8 1.6 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain E1-E2_ATPase PF00122.20 EAQ91728.1 - 2.8e-40 137.8 3.9 1.1e-38 132.5 0.5 2.7 3 0 0 3 3 3 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 EAQ91728.1 - 2.8e-33 115.2 1.5 2.8e-33 115.2 1.5 3.1 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EAQ91728.1 - 6.5e-27 95.2 0.2 5.2e-26 92.2 0.2 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EAQ91728.1 - 3.2e-14 52.8 0.0 6.1e-14 51.9 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 EAQ91728.1 - 2.7e-10 39.8 0.0 8.5e-10 38.2 0.0 1.9 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EAQ91728.1 - 0.0017 18.1 0.1 0.0037 17.0 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF2157 PF09925.9 EAQ91728.1 - 0.0061 16.3 5.1 0.0077 16.0 0.0 2.8 3 0 0 3 3 3 1 Predicted membrane protein (DUF2157) DUF2207 PF09972.9 EAQ91728.1 - 4.2 6.0 6.3 16 4.1 0.0 2.9 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) Zn_clus PF00172.18 EAQ91729.1 - 3.1e-05 24.0 8.4 3.1e-05 24.0 8.4 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.26 EAQ91729.1 - 0.0055 17.1 2.4 0.0055 17.1 2.4 2.6 2 0 0 2 2 2 1 Zinc finger, C2H2 type Ferric_reduct PF01794.19 EAQ91732.1 - 3.4e-19 69.2 10.2 3.4e-19 69.2 10.2 1.8 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 EAQ91732.1 - 8e-14 51.7 0.0 1.7e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 EAQ91732.1 - 4.9e-13 49.5 0.0 7.3e-13 48.9 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain tRNA-synt_1d PF00750.19 EAQ91733.1 - 1.3e-99 333.5 2.6 1.7e-99 333.1 2.6 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 EAQ91733.1 - 6.4e-26 90.9 0.2 1.7e-25 89.5 0.2 1.8 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 EAQ91733.1 - 8.2e-05 23.1 0.0 0.00031 21.3 0.0 2.0 2 0 0 2 2 2 1 Arginyl tRNA synthetase N terminal domain p450 PF00067.22 EAQ91734.1 - 8.2e-57 193.0 0.0 1e-56 192.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Iron_traffic PF04362.14 EAQ91734.1 - 0.029 14.1 0.0 0.41 10.4 0.0 2.3 2 0 0 2 2 2 0 Bacterial Fe(2+) trafficking FAD_binding_4 PF01565.23 EAQ91735.1 - 1.1e-29 103.0 5.6 1.6e-29 102.5 5.6 1.2 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EAQ91735.1 - 4.9e-12 45.8 0.0 9.7e-12 44.8 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like SLAC1 PF03595.17 EAQ91736.1 - 1.1e-83 281.2 40.2 1.1e-83 281.2 40.2 5.3 6 1 0 6 6 6 1 Voltage-dependent anion channel RINGv PF12906.7 EAQ91736.1 - 0.005 16.9 0.2 0.011 15.9 0.2 1.5 1 0 0 1 1 1 1 RING-variant domain HeLo PF14479.6 EAQ91738.1 - 6.4e-10 39.2 6.0 0.00011 22.2 0.1 3.6 2 1 0 3 3 3 3 Prion-inhibition and propagation DUF3405 PF11885.8 EAQ91739.1 - 1e-138 463.2 1.2 1.3e-138 462.8 1.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) PEP-CTERM PF07589.11 EAQ91739.1 - 1.2 9.3 7.2 2.7 8.2 2.2 2.5 2 0 0 2 2 2 0 PEP-CTERM motif HATPase_c PF02518.26 EAQ91740.1 - 1e-20 74.3 0.1 2.4e-20 73.1 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EAQ91740.1 - 2.2e-20 72.9 0.0 5.3e-20 71.7 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 EAQ91740.1 - 1.1e-08 35.0 0.2 4.4e-08 33.1 0.2 2.1 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Glyco_hydro_61 PF03443.14 EAQ91741.1 - 1.7e-68 230.6 0.1 2e-68 230.4 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Big_3_4 PF13754.6 EAQ91741.1 - 0.078 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function Sugar_tr PF00083.24 EAQ91742.1 - 2.1e-84 284.0 20.3 2.6e-84 283.7 20.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EAQ91742.1 - 5.5e-23 81.5 25.4 5.5e-23 81.5 25.4 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EAQ91742.1 - 2e-06 26.6 1.9 4e-06 25.6 1.9 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) GMC_oxred_N PF00732.19 EAQ91743.1 - 4.9e-31 108.2 0.1 8e-31 107.5 0.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EAQ91743.1 - 2.1e-29 102.9 0.0 3.3e-29 102.2 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase pKID PF02173.17 EAQ91743.1 - 0.14 11.7 0.2 0.28 10.7 0.2 1.4 1 0 0 1 1 1 0 pKID domain Apolipoprotein PF01442.18 EAQ91744.1 - 0.00027 20.9 12.2 0.0016 18.3 10.0 2.9 2 1 0 2 2 2 1 Apolipoprotein A1/A4/E domain DUF948 PF06103.11 EAQ91744.1 - 0.0022 18.2 5.4 4.2 7.7 0.0 5.0 2 1 3 5 5 5 1 Bacterial protein of unknown function (DUF948) Tam41_Mmp37 PF09139.11 EAQ91744.1 - 0.056 12.9 0.2 0.12 11.8 0.1 1.8 2 0 0 2 2 2 0 Phosphatidate cytidylyltransferase, mitochondrial TetR_C_24 PF17932.1 EAQ91744.1 - 0.11 12.8 0.1 2 8.7 0.0 3.0 3 1 1 4 4 4 0 Tetracyclin repressor-like, C-terminal domain FAM184 PF15665.5 EAQ91744.1 - 0.19 11.5 12.0 1.2 8.8 0.8 3.5 3 1 1 4 4 4 0 Family with sequence similarity 184, A and B DUF3223 PF11523.8 EAQ91744.1 - 0.38 11.6 2.7 6.2 7.8 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3223) ApoLp-III PF07464.11 EAQ91744.1 - 0.72 9.9 15.7 7.3 6.7 0.0 4.5 2 1 2 4 4 4 0 Apolipophorin-III precursor (apoLp-III) KdpC PF02669.15 EAQ91744.1 - 1 9.2 3.2 3 7.7 0.2 2.7 2 1 0 2 2 2 0 K+-transporting ATPase, c chain DCB PF16213.5 EAQ91744.1 - 1 9.0 4.0 4.5 6.9 1.7 2.5 2 0 0 2 2 2 0 Dimerisation and cyclophilin-binding domain of Mon2 ZYG-11_interact PF05884.12 EAQ91744.1 - 4.6 6.6 4.4 12 5.2 0.3 2.6 2 1 1 3 3 3 0 Interactor of ZYG-11 Glyco_hydro_10 PF00331.20 EAQ91745.1 - 7.2e-80 268.5 0.0 9.5e-80 268.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 TrkH PF02386.16 EAQ91747.1 - 2.4e-87 293.5 7.5 4.7e-85 285.9 0.1 2.1 2 0 0 2 2 2 2 Cation transport protein Ion_trans_2 PF07885.16 EAQ91747.1 - 2 8.5 8.6 0.27 11.2 3.2 2.4 2 0 0 2 2 2 0 Ion channel MFS_1 PF07690.16 EAQ91748.1 - 3.4e-34 118.3 24.8 3.4e-34 118.3 24.8 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EAQ91748.1 - 8.5e-08 31.5 11.4 8.5e-08 31.5 11.4 3.1 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 EAQ91748.1 - 3.5e-06 25.7 4.6 3.5e-06 25.7 4.6 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Trp_DMAT PF11991.8 EAQ91749.1 - 6.8e-63 213.3 0.0 8.7e-44 150.4 0.0 2.0 1 1 1 2 2 2 2 Tryptophan dimethylallyltransferase Aminotran_MocR PF12897.7 EAQ91751.1 - 0.00061 18.7 0.0 0.51 9.1 0.0 2.6 2 1 1 3 3 3 2 Alanine-glyoxylate amino-transferase Aminotran_1_2 PF00155.21 EAQ91751.1 - 0.0015 17.8 0.0 2 7.5 0.0 2.9 1 1 2 3 3 3 3 Aminotransferase class I and II AMP-binding PF00501.28 EAQ91752.1 - 7e-52 176.4 0.0 9.4e-52 176.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Thioesterase PF00975.20 EAQ91752.1 - 1.3e-24 87.6 0.0 4.6e-24 85.8 0.0 1.9 1 1 0 1 1 1 1 Thioesterase domain PP-binding PF00550.25 EAQ91752.1 - 0.0011 19.3 0.2 0.0011 19.3 0.2 1.9 2 0 0 2 2 2 1 Phosphopantetheine attachment site GH3 PF03321.13 EAQ91752.1 - 0.11 11.4 0.0 2.8 6.7 0.0 2.1 2 0 0 2 2 2 0 GH3 auxin-responsive promoter Hydrolase_4 PF12146.8 EAQ91752.1 - 0.11 11.7 0.0 0.24 10.6 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 NapE PF06796.11 EAQ91753.1 - 0.066 12.7 2.0 0.22 11.1 2.0 1.8 1 0 0 1 1 1 0 Periplasmic nitrate reductase protein NapE GMC_oxred_C PF05199.13 EAQ91754.1 - 1.6e-30 106.5 0.0 3.1e-30 105.6 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 EAQ91754.1 - 2.4e-30 105.9 0.1 2.2e-27 96.2 0.1 2.8 2 1 0 2 2 2 2 GMC oxidoreductase NAD_binding_8 PF13450.6 EAQ91754.1 - 0.001 19.2 0.0 0.0028 17.8 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EAQ91754.1 - 0.011 15.0 0.0 0.02 14.1 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EAQ91754.1 - 0.033 13.3 0.0 0.067 12.3 0.0 1.5 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.14 EAQ91754.1 - 0.041 12.6 0.1 0.072 11.8 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 EAQ91754.1 - 0.047 12.9 0.0 9 5.4 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EAQ91754.1 - 0.053 13.1 1.3 0.13 11.8 1.3 1.9 1 1 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EAQ91754.1 - 0.082 12.1 0.2 0.12 11.6 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain ABC2_membrane PF01061.24 EAQ91755.1 - 1.6e-82 276.0 49.4 2.7e-45 154.4 24.8 2.2 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 EAQ91755.1 - 2.1e-36 125.5 0.0 5e-18 65.9 0.0 2.3 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 EAQ91755.1 - 3.5e-25 87.7 8.7 1.5e-23 82.5 0.0 3.7 3 0 0 3 3 3 2 CDR ABC transporter AAA_16 PF13191.6 EAQ91755.1 - 1.1e-06 29.2 0.1 0.0018 18.7 0.1 2.4 2 0 0 2 2 2 2 AAA ATPase domain ABC2_membrane_3 PF12698.7 EAQ91755.1 - 1.2e-06 27.9 34.5 0.0015 17.7 8.7 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_25 PF13481.6 EAQ91755.1 - 7.1e-05 22.5 0.3 0.0056 16.3 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EAQ91755.1 - 9.4e-05 22.1 0.6 0.08 12.7 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_trans_N PF14510.6 EAQ91755.1 - 0.00022 21.8 0.0 0.00049 20.6 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_18 PF13238.6 EAQ91755.1 - 0.00067 20.2 0.0 1.1 9.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 EAQ91755.1 - 0.00088 19.2 0.2 0.0049 16.8 0.1 2.0 2 0 0 2 2 2 1 RsgA GTPase AAA_28 PF13521.6 EAQ91755.1 - 0.0015 18.8 1.7 0.89 9.8 0.6 2.4 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 EAQ91755.1 - 0.002 18.4 0.0 0.87 9.9 0.0 2.8 3 0 0 3 3 3 1 AAA domain cobW PF02492.19 EAQ91755.1 - 0.016 14.8 1.5 2.1 7.9 0.4 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 EAQ91755.1 - 0.03 14.5 0.0 1.5 9.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EAQ91755.1 - 0.046 13.6 0.3 2.6 7.9 0.1 2.3 2 0 0 2 2 2 0 NACHT domain PduV-EutP PF10662.9 EAQ91755.1 - 0.05 13.3 0.2 7.1 6.4 0.2 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_30 PF13604.6 EAQ91755.1 - 0.085 12.6 0.6 5.2 6.7 0.3 2.5 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 EAQ91755.1 - 0.087 12.9 0.3 20 5.3 0.1 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_21 PF13304.6 EAQ91755.1 - 0.13 12.0 0.0 4.1 7.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Zeta_toxin PF06414.12 EAQ91755.1 - 0.43 9.8 2.3 3.6 6.8 0.3 2.6 3 0 0 3 3 3 0 Zeta toxin ABC2_membrane_2 PF12679.7 EAQ91755.1 - 4.4 6.5 14.7 0.14 11.4 6.4 2.2 2 0 0 2 2 2 0 ABC-2 family transporter protein Fungal_trans PF04082.18 EAQ91756.1 - 2.8e-09 36.4 0.1 6e-09 35.3 0.1 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EAQ91756.1 - 1.5e-07 31.4 10.0 2.9e-07 30.5 10.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_61 PF03443.14 EAQ91757.1 - 2e-66 223.8 0.6 2.4e-66 223.6 0.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Gag_p10 PF02337.17 EAQ91757.1 - 0.15 12.0 0.5 0.28 11.1 0.5 1.4 1 0 0 1 1 1 0 Retroviral GAG p10 protein RVT_1 PF00078.27 EAQ91759.1 - 2.6e-19 69.7 0.0 1.8e-10 40.7 0.0 2.3 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 EAQ91759.1 - 0.00038 20.4 3.7 0.00038 20.4 3.7 2.7 2 0 0 2 2 2 1 Zinc knuckle zf-RVT PF13966.6 EAQ91759.1 - 0.067 13.9 0.2 0.067 13.9 0.2 3.3 3 0 0 3 3 3 0 zinc-binding in reverse transcriptase DDE_1 PF03184.19 EAQ91760.1 - 3.4e-09 36.6 0.0 6.1e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.16 EAQ91760.1 - 9.6e-09 34.9 0.1 2.3e-08 33.7 0.1 1.7 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.16 EAQ91760.1 - 4.4e-08 33.0 0.0 1.3e-07 31.5 0.0 1.8 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain SpoIIID PF12116.8 EAQ91760.1 - 0.024 14.7 0.0 0.056 13.5 0.0 1.6 1 0 0 1 1 1 0 Stage III sporulation protein D HTH_23 PF13384.6 EAQ91760.1 - 0.048 13.5 0.2 0.26 11.2 0.1 2.2 2 0 0 2 2 2 0 Homeodomain-like domain RT_RNaseH_2 PF17919.1 EAQ91761.1 - 1e-13 51.1 0.0 2.8e-05 24.1 0.0 2.9 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 EAQ91761.1 - 1.2e-12 48.0 0.0 3.5e-12 46.5 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 EAQ91761.1 - 1.5e-09 37.7 0.0 4.5e-09 36.2 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 EAQ91761.1 - 2.9e-09 37.2 0.0 8.4e-09 35.7 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 EAQ91761.1 - 7e-07 29.1 0.2 1.8e-06 27.8 0.0 1.8 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Integrase_H2C2 PF17921.1 EAQ91761.1 - 4.9e-05 23.4 0.3 0.00018 21.5 0.1 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain Tudor-knot PF11717.8 EAQ91761.1 - 0.039 13.8 0.0 0.13 12.2 0.0 1.9 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain zf-C2H2_4 PF13894.6 EAQ91761.1 - 1.6 9.8 8.4 0.084 13.8 1.0 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger OrsD PF12013.8 EAQ91762.1 - 3.3e-20 72.7 0.5 6.9e-20 71.6 0.5 1.6 1 0 0 1 1 1 1 Orsellinic acid/F9775 biosynthesis cluster protein D DEAD PF00270.29 EAQ91762.1 - 9.7e-10 38.5 0.1 2.7e-09 37.0 0.1 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EAQ91762.1 - 2.7e-08 34.1 0.0 5.8e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EAQ91762.1 - 1.7e-07 31.4 0.0 6.3e-07 29.5 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit TPR_10 PF13374.6 EAQ91766.1 - 1.5e-146 473.0 9.3 8.7e-14 50.9 0.0 12.4 11 1 1 12 12 12 12 Tetratricopeptide repeat TPR_12 PF13424.6 EAQ91766.1 - 4.9e-113 369.6 6.6 2.4e-16 59.8 0.1 10.3 2 2 8 10 10 10 10 Tetratricopeptide repeat TPR_7 PF13176.6 EAQ91766.1 - 2.2e-62 202.6 3.2 6.7e-05 22.6 0.1 11.5 11 0 0 11 11 11 11 Tetratricopeptide repeat TPR_17 PF13431.6 EAQ91766.1 - 1.2e-27 94.3 1.4 0.92 10.0 0.0 10.1 11 0 0 11 11 9 9 Tetratricopeptide repeat TPR_2 PF07719.17 EAQ91766.1 - 5.1e-23 79.3 0.0 1.7 8.9 0.0 11.3 11 0 0 11 11 11 4 Tetratricopeptide repeat TPR_19 PF14559.6 EAQ91766.1 - 6.7e-23 81.0 0.0 0.049 14.1 0.0 10.6 4 3 7 11 11 11 4 Tetratricopeptide repeat TPR_1 PF00515.28 EAQ91766.1 - 3.5e-22 77.2 0.1 4.5 7.3 0.0 10.7 11 0 0 11 11 10 4 Tetratricopeptide repeat TPR_16 PF13432.6 EAQ91766.1 - 4e-22 78.6 0.0 0.6 10.8 0.0 10.9 8 2 3 11 11 11 2 Tetratricopeptide repeat TPR_4 PF07721.14 EAQ91766.1 - 1.9e-19 68.2 0.0 7.2 7.6 0.0 11.7 12 0 0 12 12 11 0 Tetratricopeptide repeat TPR_MalT PF17874.1 EAQ91766.1 - 1e-16 61.2 18.3 3.7e-07 29.9 1.6 3.7 3 1 1 4 4 4 3 MalT-like TPR region TPR_8 PF13181.6 EAQ91766.1 - 4.6e-13 48.2 6.0 18 5.8 0.0 10.1 10 0 0 10 10 10 0 Tetratricopeptide repeat TPR_5 PF12688.7 EAQ91766.1 - 4.3e-11 43.1 3.1 0.12 12.6 0.0 6.8 4 2 2 7 7 7 1 Tetratrico peptide repeat PPR PF01535.20 EAQ91766.1 - 1.3e-09 37.7 1.8 2e+02 2.6 0.0 10.6 11 0 0 11 11 11 0 PPR repeat TPR_14 PF13428.6 EAQ91766.1 - 1.8e-09 37.6 1.5 89 4.3 0.0 10.2 11 0 0 11 11 10 0 Tetratricopeptide repeat RBD-FIP PF09457.10 EAQ91766.1 - 3.9e-06 26.7 2.7 50 3.9 0.0 7.2 5 0 0 5 5 5 0 FIP domain N36 PF11438.8 EAQ91766.1 - 3.8e-05 23.4 6.6 84 3.1 0.0 8.6 11 0 0 11 11 11 0 36-mer N-terminal peptide of the N protein (N36) DUF1897 PF09005.10 EAQ91766.1 - 9e-05 21.9 10.5 1e+02 2.5 0.0 9.4 10 0 0 10 10 10 0 Domain of unknown function (DUF1897) RPN6_N PF18055.1 EAQ91766.1 - 0.00092 19.6 14.3 2.2 8.7 0.1 6.2 6 0 0 6 6 6 2 26S proteasome regulatory subunit RPN6 N-terminal domain RVT_3 PF13456.6 EAQ91766.1 - 0.001 18.8 0.0 0.0025 17.6 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase-like zf-RVT PF13966.6 EAQ91766.1 - 0.015 16.0 0.2 0.057 14.1 0.2 2.0 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase TPR_6 PF13174.6 EAQ91766.1 - 0.055 14.1 10.2 93 4.0 0.0 7.3 9 0 0 9 9 5 0 Tetratricopeptide repeat Spore_YpjB PF09577.10 EAQ91766.1 - 0.055 13.3 2.0 12 5.6 0.0 3.4 3 0 0 3 3 3 0 Sporulation protein YpjB (SpoYpjB) RVT_1 PF00078.27 EAQ91766.1 - 0.083 12.4 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Trans_reg_C PF00486.28 EAQ91766.1 - 0.087 12.9 8.4 4.6 7.4 0.0 6.4 4 2 4 8 8 8 0 Transcriptional regulatory protein, C terminal RPN7 PF10602.9 EAQ91766.1 - 0.089 12.5 0.1 7.7 6.2 0.0 3.8 2 1 1 3 3 3 0 26S proteasome subunit RPN7 GCSF PF16647.5 EAQ91766.1 - 0.16 11.8 0.0 0.41 10.5 0.0 1.7 1 0 0 1 1 1 0 Granulocyte colony-stimulating factor RVT_1 PF00078.27 EAQ91768.1 - 2.4e-10 40.3 0.0 1.2e-09 38.0 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) UDPG_MGDP_dh_C PF03720.15 EAQ91768.1 - 0.13 12.6 0.2 0.48 10.9 0.2 1.9 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Peptidase_S41 PF03572.18 EAQ91769.1 - 0.00017 21.2 0.0 0.00026 20.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase family S41 ABC_membrane PF00664.23 EAQ91770.1 - 4.1e-44 151.3 12.0 5.4e-44 150.9 12.0 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EAQ91770.1 - 1.6e-32 112.8 0.0 3.8e-32 111.7 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EAQ91770.1 - 3.6e-06 26.6 0.0 0.0013 18.2 0.0 2.3 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EAQ91770.1 - 6.3e-06 26.7 0.0 1.3e-05 25.6 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EAQ91770.1 - 0.00019 21.7 0.0 0.0031 17.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 EAQ91770.1 - 0.00077 19.3 0.1 0.05 13.4 0.0 2.3 1 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_14 PF13173.6 EAQ91770.1 - 0.0011 19.0 0.0 0.016 15.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 EAQ91770.1 - 0.0037 17.7 0.0 0.025 15.0 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 EAQ91770.1 - 0.0048 16.8 0.0 0.016 15.1 0.0 1.8 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 EAQ91770.1 - 0.015 15.4 0.0 0.039 14.0 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase ATPase_2 PF01637.18 EAQ91770.1 - 0.024 14.5 0.0 0.23 11.4 0.0 2.4 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_25 PF13481.6 EAQ91770.1 - 0.026 14.1 0.0 0.079 12.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EAQ91770.1 - 0.027 14.2 0.1 0.068 12.9 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 EAQ91770.1 - 0.028 13.7 0.0 0.12 11.6 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin AAA_18 PF13238.6 EAQ91770.1 - 0.028 14.9 0.0 0.11 13.1 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EAQ91770.1 - 0.031 14.5 0.0 0.1 12.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EAQ91770.1 - 0.038 14.2 0.0 0.094 12.9 0.0 1.7 2 0 0 2 2 1 0 AAA domain YwiC PF14256.6 EAQ91770.1 - 0.039 14.3 0.5 0.098 13.0 0.5 1.7 1 0 0 1 1 1 0 YwiC-like protein AAA_7 PF12775.7 EAQ91770.1 - 0.043 13.3 0.0 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region Rad17 PF03215.15 EAQ91770.1 - 0.055 13.4 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_24 PF13479.6 EAQ91770.1 - 0.08 12.7 0.0 0.23 11.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 EAQ91770.1 - 0.092 13.0 0.4 1.7 8.9 0.4 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.6 EAQ91770.1 - 0.1 12.3 0.1 0.24 11.1 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain NACHT PF05729.12 EAQ91770.1 - 0.13 12.2 0.0 0.51 10.2 0.0 2.0 3 0 0 3 3 2 0 NACHT domain Kinesin PF00225.23 EAQ91771.1 - 4.5e-72 242.8 0.2 6.3e-72 242.3 0.2 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EAQ91771.1 - 4.1e-13 49.5 0.0 7.7e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding FAS_I_H PF18314.1 EAQ91771.1 - 2.3 7.8 4.8 2.1 7.9 0.2 2.9 3 0 0 3 3 3 0 Fatty acid synthase type I helical domain DUF1690 PF07956.11 EAQ91771.1 - 2.7 8.4 5.8 0.53 10.7 0.8 2.3 3 0 0 3 3 3 0 Protein of Unknown function (DUF1690) AIM24 PF01987.17 EAQ91772.1 - 7.5e-36 123.8 0.0 1e-35 123.4 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 Peptidase_S8 PF00082.22 EAQ91774.1 - 3.8e-05 23.1 0.1 0.0012 18.2 0.0 2.3 1 1 1 2 2 2 2 Subtilase family Ank_2 PF12796.7 EAQ91774.1 - 0.00031 21.3 0.0 0.00095 19.7 0.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) NUDIX_4 PF14815.6 EAQ91776.1 - 9.1e-20 70.7 0.0 2.2e-19 69.4 0.0 1.7 1 0 0 1 1 1 1 NUDIX domain HhH-GPD PF00730.25 EAQ91776.1 - 5.1e-13 49.4 0.0 1.1e-12 48.3 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 EAQ91776.1 - 4.2e-07 29.5 0.2 1.1e-06 28.2 0.2 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif UvrD_C_2 PF13538.6 EAQ91776.1 - 0.00036 20.3 0.0 0.001 18.9 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain PIF1 PF05970.14 EAQ91776.1 - 0.0022 17.2 0.0 0.0036 16.5 0.0 1.3 1 0 0 1 1 1 1 PIF1-like helicase Herpes_Helicase PF02689.14 EAQ91776.1 - 0.0032 15.5 0.0 0.0048 14.9 0.0 1.1 1 0 0 1 1 1 1 Helicase CCDC106 PF15794.5 EAQ91776.1 - 0.22 11.2 1.0 0.37 10.5 1.0 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 BUD22 PF09073.10 EAQ91776.1 - 0.36 10.1 4.8 0.74 9.1 4.8 1.4 1 0 0 1 1 1 0 BUD22 zf-RING_7 PF02591.15 EAQ91776.1 - 0.69 10.1 2.9 1.3 9.3 0.0 2.5 2 0 0 2 2 2 0 C4-type zinc ribbon domain FAA_hydrolase PF01557.18 EAQ91778.1 - 2.8e-65 220.1 0.0 3.3e-65 219.8 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family p450 PF00067.22 EAQ91779.1 - 1.6e-63 215.1 0.0 2.9e-52 178.0 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 FAD_binding_3 PF01494.19 EAQ91780.1 - 2.5e-81 273.7 0.0 3.4e-81 273.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EAQ91780.1 - 0.012 14.9 0.2 0.022 14.0 0.2 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EAQ91780.1 - 0.1 12.8 2.1 0.25 11.6 2.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EAQ91780.1 - 0.14 11.2 0.2 0.21 10.6 0.2 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.17 EAQ91780.1 - 0.2 10.9 0.3 0.32 10.2 0.3 1.3 1 0 0 1 1 1 0 Thi4 family Glyoxalase PF00903.25 EAQ91781.1 - 1.1e-08 35.3 6.1 2.3e-05 24.6 3.2 2.5 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 EAQ91781.1 - 8.9e-05 22.7 0.1 0.011 16.0 0.1 2.4 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Isochorismatase PF00857.20 EAQ91782.1 - 2.1e-18 67.1 0.0 2.5e-18 66.8 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family DHDPS PF00701.22 EAQ91783.1 - 4.9e-29 100.9 0.0 6.4e-29 100.6 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Abhydrolase_6 PF12697.7 EAQ91784.1 - 2e-05 25.3 1.6 3.2e-05 24.7 1.6 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EAQ91784.1 - 0.001 18.8 0.1 0.0018 18.0 0.1 1.4 2 0 0 2 2 2 1 alpha/beta hydrolase fold DPM3 PF08285.11 EAQ91784.1 - 0.05 13.8 0.2 3.3 8.0 0.0 2.2 2 0 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Orbi_VP5 PF00901.17 EAQ91784.1 - 0.17 10.3 0.0 0.23 9.8 0.0 1.1 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 MHYT PF03707.16 EAQ91785.1 - 1.1e-23 83.1 21.1 6.2e-11 42.3 0.8 4.9 4 0 0 4 4 4 4 Bacterial signalling protein N terminal repeat DUF2644 PF10841.8 EAQ91785.1 - 0.1 12.8 0.2 0.71 10.1 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2644) Fumarate_red_D PF02313.17 EAQ91785.1 - 2.6 8.2 7.9 0.83 9.8 0.9 2.9 1 1 2 3 3 3 0 Fumarate reductase subunit D PDR_CDR PF06422.12 EAQ91785.1 - 8.5 6.3 6.2 0.85 9.6 0.7 2.1 2 0 0 2 2 2 0 CDR ABC transporter Fringe PF02434.16 EAQ91786.1 - 1.4e-05 24.6 0.0 2.3e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Fringe-like PAN_4 PF14295.6 EAQ91786.1 - 0.012 15.5 0.9 0.024 14.5 0.9 1.5 1 0 0 1 1 1 0 PAN domain adh_short PF00106.25 EAQ91787.1 - 3e-40 137.8 0.5 4.5e-40 137.2 0.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EAQ91787.1 - 1.1e-26 93.9 2.4 1.6e-26 93.3 2.4 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EAQ91787.1 - 9.7e-06 25.6 1.2 1.6e-05 24.9 1.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EAQ91787.1 - 0.00051 19.6 0.2 0.00081 18.9 0.2 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EAQ91787.1 - 0.0026 16.9 0.5 0.0047 16.1 0.5 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 EAQ91787.1 - 0.058 13.3 2.9 0.17 11.8 2.9 1.9 1 1 0 1 1 1 0 NAD(P)H-binding DUF1776 PF08643.10 EAQ91787.1 - 0.12 11.7 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Septum_form PF13845.6 EAQ91788.1 - 0.027 14.0 0.0 0.031 13.8 0.0 1.1 1 0 0 1 1 1 0 Septum formation Cutinase PF01083.22 EAQ91789.1 - 1.1e-52 178.6 6.3 1.5e-52 178.2 6.3 1.2 1 0 0 1 1 1 1 Cutinase CBM_1 PF00734.18 EAQ91789.1 - 1.4e-11 44.1 19.7 1.4e-11 44.1 19.7 2.9 3 0 0 3 3 3 1 Fungal cellulose binding domain PE-PPE PF08237.11 EAQ91789.1 - 0.00045 19.8 0.1 0.00084 19.0 0.1 1.4 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_1 PF00561.20 EAQ91789.1 - 0.0012 18.6 0.1 0.0014 18.3 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EAQ91789.1 - 0.0014 19.3 0.3 0.0019 18.8 0.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EAQ91789.1 - 0.052 12.8 0.0 0.068 12.4 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 VirJ PF06057.11 EAQ91789.1 - 0.19 11.6 0.0 0.34 10.8 0.0 1.3 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Fungal_trans_2 PF11951.8 EAQ91790.1 - 9.7e-05 21.3 0.0 0.00015 20.7 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.25 EAQ91791.1 - 6.5e-20 71.4 0.0 5.5e-16 58.6 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EAQ91791.1 - 2.9e-12 46.7 0.0 5.3e-08 32.7 0.0 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EAQ91791.1 - 7e-06 26.1 0.0 1e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EAQ91791.1 - 0.044 13.2 0.0 0.38 10.2 0.0 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Hexapep PF00132.24 EAQ91792.1 - 1.2e-05 24.8 20.0 0.00047 19.8 8.4 2.8 1 1 1 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Peptidase_M28 PF04389.17 EAQ91794.1 - 1.2e-40 139.4 0.0 1.9e-40 138.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 EAQ91794.1 - 8.1e-10 38.6 0.1 2.3e-09 37.1 0.1 1.8 2 0 0 2 2 2 1 PA domain Peptidase_M20 PF01546.28 EAQ91794.1 - 8.9e-06 25.5 0.0 1.4e-05 24.9 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Glyco_hydro_10 PF00331.20 EAQ91795.1 - 1.7e-102 342.8 0.0 2e-102 342.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_1 PF00734.18 EAQ91795.1 - 7.6e-14 51.4 12.6 2e-13 50.1 12.6 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain Hemerythrin PF01814.23 EAQ91796.1 - 9.2e-14 52.2 3.9 1.8e-13 51.3 3.5 1.7 2 1 0 2 2 2 1 Hemerythrin HHE cation binding domain DUF1031 PF06275.11 EAQ91796.1 - 0.0082 16.4 0.1 0.015 15.5 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1031) Hpt PF01627.23 EAQ91796.1 - 0.19 12.0 2.3 0.69 10.2 1.3 2.2 2 0 0 2 2 2 0 Hpt domain FCD PF07729.12 EAQ91796.1 - 0.86 10.0 4.9 1.2 9.6 0.1 2.3 2 1 1 3 3 3 0 FCD domain Fungal_trans_2 PF11951.8 EAQ91797.1 - 9.3e-06 24.7 2.9 1.3e-05 24.2 2.9 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EAQ91797.1 - 0.00064 19.8 1.8 0.0012 18.9 1.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.22 EAQ91798.1 - 1.7e-52 178.8 0.0 2.3e-52 178.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 NACHT_N PF17100.5 EAQ91799.1 - 3.5e-05 23.8 0.1 0.00013 21.9 0.1 1.7 1 1 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase Abhydrolase_1 PF00561.20 EAQ91800.1 - 2.2e-07 30.8 0.1 4.5e-07 29.8 0.1 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EAQ91800.1 - 3.5e-07 31.1 4.3 4.7e-07 30.6 4.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EAQ91800.1 - 0.02 14.2 0.3 0.031 13.6 0.3 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Thioesterase PF00975.20 EAQ91800.1 - 0.032 14.3 0.1 0.038 14.1 0.1 1.2 1 0 0 1 1 1 0 Thioesterase domain DUF2196 PF09962.9 EAQ91802.1 - 4.5e-24 84.2 2.3 7.9e-24 83.4 2.3 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2196) DUF3618 PF12277.8 EAQ91802.1 - 0.028 14.7 0.5 0.093 13.0 0.5 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3618) FlxA PF14282.6 EAQ91802.1 - 0.11 12.6 0.4 0.11 12.6 0.4 1.8 2 0 0 2 2 2 0 FlxA-like protein zf-Di19 PF05605.12 EAQ91802.1 - 0.31 11.4 0.3 0.31 11.4 0.3 1.9 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding NmrA PF05368.13 EAQ91803.1 - 1.4e-24 86.9 1.6 9.5e-23 81.0 0.9 2.1 1 1 1 2 2 2 2 NmrA-like family NAD_binding_10 PF13460.6 EAQ91803.1 - 7.5e-09 35.7 1.5 1.1e-08 35.2 1.5 1.2 1 0 0 1 1 1 1 NAD(P)H-binding HD PF01966.22 EAQ91805.1 - 0.036 14.3 0.1 0.056 13.7 0.1 1.3 1 0 0 1 1 1 0 HD domain AMP-binding PF00501.28 EAQ91806.1 - 1.6e-31 109.3 0.0 2.5e-31 108.7 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 EAQ91806.1 - 2.1e-28 99.2 0.0 3.3e-28 98.5 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 EAQ91806.1 - 1.9e-10 40.6 0.0 3.1e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 EAQ91806.1 - 0.00055 20.2 0.0 0.0018 18.6 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site GDP_Man_Dehyd PF16363.5 EAQ91806.1 - 0.06 12.7 0.0 0.096 12.1 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Sugar_tr PF00083.24 EAQ91807.1 - 3.5e-33 115.1 25.7 5.2e-22 78.3 8.0 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EAQ91807.1 - 2.2e-08 33.5 38.2 2.7e-07 29.8 14.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily BDV_P40 PF06407.11 EAQ91808.1 - 0.56 9.3 7.6 14 4.6 0.7 2.9 1 1 2 3 3 3 0 Borna disease virus P40 protein p450 PF00067.22 EAQ91809.1 - 6.8e-51 173.5 0.0 7.8e-51 173.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FeS_assembly_P PF01883.19 EAQ91809.1 - 0.077 13.2 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 Iron-sulfur cluster assembly protein FSH1 PF03959.13 EAQ91810.1 - 2e-23 83.2 0.0 3.4e-23 82.4 0.0 1.4 1 1 0 1 1 1 1 Serine hydrolase (FSH1) CDC45 PF02724.14 EAQ91810.1 - 0.015 13.6 2.9 0.017 13.4 2.9 1.1 1 0 0 1 1 1 0 CDC45-like protein CobT PF06213.12 EAQ91810.1 - 0.04 13.3 10.1 0.06 12.7 10.1 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT BUD22 PF09073.10 EAQ91810.1 - 0.07 12.5 6.3 0.09 12.1 6.3 1.1 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 EAQ91810.1 - 0.071 12.5 10.6 0.093 12.1 10.6 1.1 1 0 0 1 1 1 0 SDA1 RRN3 PF05327.11 EAQ91810.1 - 0.094 11.2 3.5 0.12 10.9 3.5 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Nop14 PF04147.12 EAQ91810.1 - 0.6 8.3 14.5 0.77 7.9 14.5 1.0 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 EAQ91810.1 - 0.91 7.6 18.5 1.4 7.0 18.5 1.2 1 0 0 1 1 1 0 DNA polymerase phi Mpp10 PF04006.12 EAQ91810.1 - 0.97 7.8 10.7 1.3 7.4 10.7 1.1 1 0 0 1 1 1 0 Mpp10 protein DARPP-32 PF05395.12 EAQ91810.1 - 2.4 8.4 7.2 4.2 7.6 7.2 1.4 1 0 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 DUF4746 PF15928.5 EAQ91810.1 - 4.9 6.5 7.1 7.6 5.9 7.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Astro_capsid_p PF12226.8 EAQ91810.1 - 8.9 5.4 10.3 12 4.9 10.3 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein ketoacyl-synt PF00109.26 EAQ91811.1 - 1.5e-72 244.2 0.0 2.6e-72 243.4 0.0 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 EAQ91811.1 - 2.6e-56 191.5 0.0 4.6e-56 190.7 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 EAQ91811.1 - 1.5e-55 187.9 0.3 3.6e-55 186.7 0.1 1.8 2 0 0 2 2 2 1 KR domain Ketoacyl-synt_C PF02801.22 EAQ91811.1 - 2.9e-31 108.0 0.0 1.2e-30 105.9 0.0 2.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.6 EAQ91811.1 - 7.6e-21 74.6 0.2 2.2e-20 73.1 0.0 1.8 2 0 0 2 2 2 1 Polyketide synthase dehydratase adh_short PF00106.25 EAQ91811.1 - 2.1e-13 50.2 0.2 5.5e-13 48.8 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase KAsynt_C_assoc PF16197.5 EAQ91811.1 - 6.2e-13 49.2 0.0 1.4e-12 48.1 0.0 1.6 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension PP-binding PF00550.25 EAQ91811.1 - 3.8e-11 43.2 0.9 8.2e-11 42.1 0.9 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short_C2 PF13561.6 EAQ91811.1 - 2.4e-08 33.9 0.0 4.5e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Thiolase_N PF00108.23 EAQ91811.1 - 1.9e-05 24.2 0.0 6.3e-05 22.4 0.0 1.9 1 0 0 1 1 1 1 Thiolase, N-terminal domain ADH_zinc_N PF00107.26 EAQ91811.1 - 0.00014 21.8 0.0 0.00064 19.7 0.0 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase SAT PF16073.5 EAQ91811.1 - 0.0064 16.3 0.1 0.013 15.3 0.1 1.5 1 0 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis ACP_syn_III PF08545.10 EAQ91811.1 - 0.0087 15.9 0.1 0.058 13.3 0.1 2.5 1 1 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ADH_N PF08240.12 EAQ91811.1 - 0.093 12.6 0.2 0.21 11.5 0.2 1.6 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain Fer4 PF00037.27 EAQ91812.1 - 4.2e-14 51.7 16.4 5.9e-08 32.2 3.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 EAQ91812.1 - 5.5e-13 49.3 10.7 8.9e-13 48.6 10.7 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 EAQ91812.1 - 8.1e-11 42.7 7.3 7.7e-05 23.5 0.3 2.4 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 EAQ91812.1 - 4e-10 39.7 4.7 7.5e-05 22.8 0.5 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 EAQ91812.1 - 3.7e-09 36.5 21.0 8.2e-07 29.0 12.1 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 EAQ91812.1 - 2.1e-08 34.2 10.1 4.2e-08 33.2 10.2 1.5 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 EAQ91812.1 - 3.1e-07 30.7 19.4 0.00011 22.5 11.6 2.2 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_6 PF12837.7 EAQ91812.1 - 7.4e-07 29.0 16.9 0.00021 21.2 5.3 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 EAQ91812.1 - 1e-06 28.5 12.2 0.0028 17.6 3.2 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 EAQ91812.1 - 2.1e-05 24.7 11.6 0.00067 20.0 2.0 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 EAQ91812.1 - 0.00014 22.3 12.2 0.026 15.0 13.3 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain c-SKI_SMAD_bind PF08782.10 EAQ91812.1 - 0.006 16.8 5.5 0.76 10.1 0.5 2.2 1 1 1 2 2 2 2 c-SKI Smad4 binding domain Fer4_18 PF13746.6 EAQ91812.1 - 0.033 14.4 9.3 0.51 10.6 1.9 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain ETF_QO PF05187.13 EAQ91812.1 - 0.046 13.8 4.9 0.24 11.6 0.3 2.2 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_13 PF13370.6 EAQ91812.1 - 0.079 13.5 14.8 0.82 10.3 4.0 2.6 2 1 1 3 3 3 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_3 PF12798.7 EAQ91812.1 - 0.089 13.8 16.6 0.41 11.7 3.3 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain EPF PF17181.4 EAQ91812.1 - 0.43 10.6 5.8 0.18 11.9 0.6 2.2 2 0 0 2 2 2 0 Epidermal patterning factor proteins Fer4_22 PF17179.4 EAQ91812.1 - 0.44 11.4 11.9 3.4 8.6 2.5 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain zf-CCCH PF00642.24 EAQ91814.1 - 6.1e-11 41.9 8.1 1.7e-05 24.6 2.1 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 EAQ91814.1 - 1.1e-10 41.0 11.2 1.6e-05 24.6 3.0 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 EAQ91814.1 - 5.5e-10 39.0 17.4 7.9e-05 22.6 4.2 2.4 2 0 0 2 2 2 2 Zinc finger domain Torus PF16131.5 EAQ91814.1 - 6.2e-09 36.5 5.8 0.00011 22.9 0.5 2.3 1 1 1 2 2 2 2 Torus domain zf-CCCH_3 PF15663.5 EAQ91814.1 - 1.8e-05 24.9 1.3 3.5e-05 24.0 1.3 1.4 1 0 0 1 1 1 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 EAQ91814.1 - 0.043 14.3 18.2 0.79 10.3 6.4 2.4 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Glyco_trans_2_3 PF13632.6 EAQ91815.1 - 8.7e-11 42.1 0.8 8.7e-11 42.1 0.8 1.7 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EAQ91815.1 - 1.7e-10 41.2 0.1 3.4e-10 40.2 0.1 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 EAQ91815.1 - 6.3e-09 35.5 0.1 1.5e-08 34.3 0.1 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 21 Chitin_synth_2 PF03142.15 EAQ91815.1 - 1.4e-06 27.3 0.2 2.1e-05 23.4 0.2 2.1 1 1 0 1 1 1 1 Chitin synthase Glycos_transf_2 PF00535.26 EAQ91815.1 - 0.13 12.1 0.0 0.41 10.5 0.0 1.8 2 0 0 2 2 2 0 Glycosyl transferase family 2 Fringe PF02434.16 EAQ91816.1 - 5.3e-07 29.3 3.1 2.2e-05 24.0 1.2 3.0 2 1 0 2 2 2 1 Fringe-like PAN_4 PF14295.6 EAQ91816.1 - 0.00086 19.2 2.7 0.0028 17.5 2.7 1.8 1 0 0 1 1 1 1 PAN domain SQHop_cyclase_N PF13249.6 EAQ91816.1 - 0.035 13.2 0.2 0.6 9.2 0.0 2.1 2 0 0 2 2 2 0 Squalene-hopene cyclase N-terminal domain Cupin_1 PF00190.22 EAQ91817.1 - 4.1e-34 117.4 0.0 6e-17 61.6 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 EAQ91817.1 - 5.4e-18 64.5 0.7 1.4e-08 34.3 0.1 2.7 3 0 0 3 3 3 2 Cupin domain Cupin_3 PF05899.12 EAQ91817.1 - 0.00012 21.7 0.0 0.085 12.6 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF861) Cupin_4 PF08007.12 EAQ91817.1 - 0.11 11.9 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Cupin superfamily protein BNR_2 PF13088.6 EAQ91818.1 - 0.0036 16.6 0.0 0.0085 15.4 0.0 1.6 1 1 0 1 1 1 1 BNR repeat-like domain MFS_1 PF07690.16 EAQ91819.1 - 4.5e-28 98.2 25.4 4.5e-28 98.2 25.4 2.4 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EAQ91819.1 - 9.2e-15 54.4 3.4 9.2e-15 54.4 3.4 2.7 2 1 1 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 EAQ91819.1 - 0.0045 15.5 3.4 0.009 14.5 3.4 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF680 PF05079.12 EAQ91819.1 - 0.2 12.4 0.4 0.41 11.4 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF680) LapA_dom PF06305.11 EAQ91819.1 - 0.59 10.0 0.0 0.59 10.0 0.0 4.0 4 0 0 4 4 4 0 Lipopolysaccharide assembly protein A domain EMP70 PF02990.16 EAQ91819.1 - 10 4.7 11.3 2 7.0 3.3 2.3 2 0 0 2 2 2 0 Endomembrane protein 70 ADC PF06314.11 EAQ91820.1 - 1.9e-10 40.7 0.0 3.6e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) FAD_binding_3 PF01494.19 EAQ91820.1 - 1.1e-09 38.1 0.1 4.8e-07 29.3 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 EAQ91820.1 - 0.011 15.9 0.1 0.034 14.4 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EAQ91820.1 - 0.015 14.6 0.0 0.026 13.8 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF1344 PF07076.11 EAQ91820.1 - 0.05 13.5 0.1 0.13 12.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1344) VWA_3_C PF18571.1 EAQ91820.1 - 0.26 11.2 0.7 0.76 9.7 0.7 1.8 1 0 0 1 1 1 0 von Willebrand factor type A C-terminal domain LigB PF02900.18 EAQ91821.1 - 2e-11 43.5 0.0 2.6e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase NUDIX PF00293.28 EAQ91823.1 - 3.1e-09 36.9 0.0 6.4e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain DUF4743 PF15916.5 EAQ91823.1 - 0.087 12.8 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4743) Peptidase_S15 PF02129.18 EAQ91824.1 - 4e-41 141.4 0.7 5.4e-41 140.9 0.7 1.1 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 EAQ91824.1 - 2.2e-24 86.7 0.0 7.5e-24 84.9 0.0 1.7 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Hydrolase_4 PF12146.8 EAQ91824.1 - 0.013 14.8 0.0 0.021 14.1 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 FAA_hydrolase PF01557.18 EAQ91825.1 - 1.9e-54 184.6 0.0 2.8e-54 184.1 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 EAQ91825.1 - 4.2e-19 68.7 0.0 1.7e-18 66.8 0.0 1.9 2 0 0 2 2 2 1 Fumarylacetoacetase N-terminal Cupin_2 PF07883.11 EAQ91826.1 - 2.1e-09 36.9 0.0 3.7e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 EAQ91826.1 - 0.0016 18.1 0.0 0.0032 17.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Aldedh PF00171.22 EAQ91827.1 - 1.5e-14 53.4 0.1 1.1e-13 50.6 0.1 2.0 1 1 0 1 1 1 1 Aldehyde dehydrogenase family NadA PF02445.16 EAQ91831.1 - 0.13 11.4 0.1 0.19 10.8 0.1 1.2 1 0 0 1 1 1 0 Quinolinate synthetase A protein YlbD_coat PF14071.6 EAQ91832.1 - 0.1 12.8 0.0 0.23 11.7 0.0 1.6 1 0 0 1 1 1 0 Putative coat protein RCR PF12273.8 EAQ91832.1 - 0.11 13.1 3.3 0.23 12.1 1.2 2.7 2 1 1 3 3 3 0 Chitin synthesis regulation, resistance to Congo red Sirohm_synth_M PF14824.6 EAQ91833.1 - 0.0038 16.6 0.1 0.008 15.6 0.1 1.6 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Methyltransf_23 PF13489.6 EAQ91834.1 - 2.8e-24 85.8 0.0 4e-24 85.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAQ91834.1 - 1.3e-10 41.9 0.0 3.6e-10 40.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EAQ91834.1 - 3.7e-08 33.9 0.0 9.2e-08 32.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAQ91834.1 - 6.2e-08 32.6 0.0 8.9e-07 28.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EAQ91834.1 - 2.4e-07 31.4 0.0 1.4e-06 29.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EAQ91834.1 - 0.00049 19.5 0.0 0.012 14.9 0.0 2.6 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 EAQ91834.1 - 0.0008 19.2 0.0 0.041 13.6 0.0 2.1 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.19 EAQ91834.1 - 0.0066 16.6 0.0 0.011 15.9 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase PrmA PF06325.13 EAQ91834.1 - 0.0089 15.4 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) GidB PF02527.15 EAQ91834.1 - 0.14 11.5 0.0 1.1 8.6 0.0 1.9 2 0 0 2 2 2 0 rRNA small subunit methyltransferase G MTS PF05175.14 EAQ91834.1 - 0.22 11.0 0.0 0.44 10.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain PIF1 PF05970.14 EAQ91836.1 - 4.9e-33 114.8 0.0 2.8e-26 92.6 0.0 2.1 2 0 0 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 EAQ91836.1 - 7.5e-12 45.4 0.0 1.6e-11 44.3 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAQ91836.1 - 1.6e-06 28.5 0.0 3.1e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain Herpes_Helicase PF02689.14 EAQ91836.1 - 3.9e-05 21.8 0.0 0.0062 14.5 0.0 2.1 2 0 0 2 2 2 2 Helicase UvrD_C_2 PF13538.6 EAQ91836.1 - 0.00014 21.6 0.1 0.00058 19.6 0.0 2.0 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain Torsin PF06309.11 EAQ91836.1 - 0.016 15.3 0.0 0.034 14.2 0.0 1.4 1 0 0 1 1 1 0 Torsin AAA_11 PF13086.6 EAQ91836.1 - 0.19 11.5 0.0 8.5 6.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EAQ91836.1 - 0.19 12.0 0.0 0.44 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 EAQ91836.1 - 0.2 11.3 0.5 6.1 6.5 0.0 2.7 2 1 0 2 2 2 0 Viral (Superfamily 1) RNA helicase RVT_1 PF00078.27 EAQ91837.1 - 2e-30 106.0 0.0 9.9e-30 103.7 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 EAQ91837.1 - 5.8e-26 90.7 0.0 1.8e-25 89.1 0.0 1.9 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase PAP2 PF01569.21 EAQ91837.1 - 1.6e-19 70.0 7.4 3.3e-19 69.0 7.4 1.5 1 0 0 1 1 1 1 PAP2 superfamily Exo_endo_phos PF03372.23 EAQ91837.1 - 0.00028 20.5 0.2 0.00067 19.2 0.2 1.7 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-CCHC PF00098.23 EAQ91837.1 - 0.0034 17.4 1.7 0.0034 17.4 1.7 3.0 3 0 0 3 3 1 1 Zinc knuckle SlyX PF04102.12 EAQ91837.1 - 0.0063 17.1 5.1 0.074 13.7 5.0 2.8 1 1 0 1 1 1 1 SlyX PAP2_3 PF14378.6 EAQ91837.1 - 0.0086 15.8 8.8 0.024 14.3 8.8 1.7 1 1 0 1 1 1 1 PAP2 superfamily USP8_interact PF08941.10 EAQ91837.1 - 0.1 12.4 0.1 0.26 11.1 0.1 1.7 1 0 0 1 1 1 0 USP8 interacting CorA PF01544.18 EAQ91837.1 - 0.1 11.9 1.5 0.22 10.8 1.5 1.5 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein CENP-F_leu_zip PF10473.9 EAQ91837.1 - 0.1 12.6 0.8 0.32 11.0 0.8 1.8 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HMMR_N PF15905.5 EAQ91837.1 - 0.12 11.9 0.4 0.2 11.1 0.4 1.2 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal PKcGMP_CC PF16808.5 EAQ91837.1 - 0.22 11.4 0.8 0.63 9.9 0.8 1.8 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF3584 PF12128.8 EAQ91837.1 - 0.84 7.1 5.6 1.3 6.4 5.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) YlqD PF11068.8 EAQ91837.1 - 1.1 9.6 3.6 3.7 7.9 3.6 1.8 1 0 0 1 1 1 0 YlqD protein DUF853 PF05872.12 EAQ91838.1 - 2.5 6.6 10.8 3.9 6.0 10.8 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) LptE PF04390.12 EAQ91838.1 - 4.6 8.0 8.2 0.62 10.8 1.9 2.5 2 1 0 2 2 2 0 Lipopolysaccharide-assembly MULE PF10551.9 EAQ91839.1 - 2.1e-07 31.3 0.0 4.3e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 MULE transposase domain Helicase_C PF00271.31 EAQ91840.1 - 1.8e-08 34.7 0.0 8.3e-08 32.6 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 EAQ91840.1 - 0.00054 19.8 0.0 0.00093 19.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF5030 PF16433.5 EAQ91840.1 - 0.0097 15.3 0.0 0.033 13.6 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF5030) PRMT5 PF05185.16 EAQ91841.1 - 0.092 12.6 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase MULE PF10551.9 EAQ91842.1 - 6.5e-16 58.5 0.3 4.3e-13 49.5 0.0 2.7 1 1 1 2 2 2 2 MULE transposase domain Transposase_mut PF00872.18 EAQ91842.1 - 0.001 18.0 0.0 0.0021 17.0 0.0 1.5 1 0 0 1 1 1 1 Transposase, Mutator family Helitron_like_N PF14214.6 EAQ91843.1 - 3.1e-15 56.9 2.1 3e-07 30.9 0.3 2.4 1 1 1 2 2 2 2 Helitron helicase-like domain at N-terminus ResIII PF04851.15 EAQ91843.1 - 0.054 13.5 0.0 0.089 12.8 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DEAD PF00270.29 EAQ91843.1 - 0.085 12.6 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase Glyco_hydro_61 PF03443.14 EAQ91845.1 - 1.1e-53 182.2 0.0 1.4e-53 181.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 RVT_2 PF07727.14 EAQ91846.1 - 5.9e-11 42.5 0.0 1.1e-10 41.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 EAQ91846.1 - 1.7e-08 34.6 0.2 1.6e-07 31.5 0.0 2.7 3 0 0 3 3 3 1 Integrase core domain gag_pre-integrs PF13976.6 EAQ91846.1 - 1.5e-05 24.7 0.4 3.8e-05 23.4 0.4 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain EI24 PF07264.11 EAQ91847.1 - 1.2e-10 41.9 13.9 2.1e-10 41.1 13.9 1.4 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) YqzE PF14038.6 EAQ91847.1 - 0.17 11.9 0.0 4.5 7.4 0.0 2.3 2 0 0 2 2 2 0 YqzE-like protein DUF2208 PF09973.9 EAQ91847.1 - 0.59 9.7 4.8 23 4.5 3.8 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2208) META PF03724.16 EAQ91849.1 - 0.056 13.4 0.1 0.11 12.5 0.1 1.4 1 0 0 1 1 1 0 META domain DUF3742 PF12553.8 EAQ91849.1 - 0.12 12.5 0.7 0.24 11.5 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3742) MFS_1 PF07690.16 EAQ91850.1 - 7.4e-15 54.7 48.4 1.2e-10 40.9 32.9 3.0 1 1 1 2 2 2 2 Major Facilitator Superfamily 7TM_GPCR_Srh PF10318.9 EAQ91850.1 - 0.12 11.4 1.1 0.28 10.2 1.1 1.5 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srh CDC27 PF09507.10 EAQ91850.1 - 0.13 11.6 0.9 0.17 11.2 0.9 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 CBP_BcsN PF17038.5 EAQ91851.1 - 0.17 11.3 0.0 0.27 10.6 0.0 1.2 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsN ketoacyl-synt PF00109.26 EAQ91852.1 - 2.4e-63 214.1 0.0 3.5e-63 213.5 0.0 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EAQ91852.1 - 5.4e-38 129.6 0.0 9.8e-38 128.8 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.21 EAQ91852.1 - 6.3e-08 32.5 0.0 1.4e-07 31.4 0.0 1.5 1 1 0 1 1 1 1 Acyl transferase domain Thiolase_N PF00108.23 EAQ91852.1 - 0.012 15.0 0.2 0.02 14.2 0.2 1.3 1 0 0 1 1 1 0 Thiolase, N-terminal domain ACP_syn_III PF08545.10 EAQ91852.1 - 0.046 13.6 0.3 0.086 12.7 0.3 1.4 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III KR PF08659.10 EAQ91853.1 - 8.8e-54 182.1 0.0 1.4e-53 181.5 0.0 1.4 1 0 0 1 1 1 1 KR domain ADH_zinc_N_2 PF13602.6 EAQ91853.1 - 6.7e-15 56.3 0.2 2.6e-14 54.4 0.0 2.1 2 0 0 2 2 1 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.12 EAQ91853.1 - 3.2e-12 47.0 0.0 7.4e-12 45.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.26 EAQ91853.1 - 1.4e-09 38.0 1.2 3.2e-09 36.8 0.2 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase PP-binding PF00550.25 EAQ91853.1 - 4e-07 30.3 0.1 1.3e-06 28.6 0.1 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_25 PF13649.6 EAQ91853.1 - 1.5e-05 25.6 0.0 4.1e-05 24.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EAQ91853.1 - 0.00016 21.6 0.0 0.00032 20.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EAQ91853.1 - 0.00017 22.1 0.0 0.00064 20.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain ADH_N PF08240.12 EAQ91853.1 - 0.00018 21.3 0.0 0.00059 19.7 0.0 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_31 PF13847.6 EAQ91853.1 - 0.00048 20.0 0.0 0.00093 19.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 EAQ91853.1 - 0.0029 17.1 0.0 0.0073 15.8 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase E1-E2_ATPase PF00122.20 EAQ91854.1 - 6.1e-38 130.1 14.0 2.4e-30 105.4 0.1 3.7 3 0 0 3 3 3 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 EAQ91854.1 - 5.6e-24 84.8 5.8 5.6e-24 84.8 5.8 2.7 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EAQ91854.1 - 1.6e-20 74.3 0.2 3.8e-17 63.3 0.0 2.7 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EAQ91854.1 - 9.2e-18 64.1 0.0 1.8e-17 63.2 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 EAQ91854.1 - 1.4e-16 59.9 1.1 9.1e-16 57.3 0.1 2.9 3 0 0 3 3 3 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EAQ91854.1 - 0.00076 19.3 0.3 0.0047 16.7 0.5 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase MFS_1 PF07690.16 EAQ91855.1 - 6.1e-23 81.3 16.0 1.8e-22 79.8 15.4 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 EAQ91855.1 - 0.00041 18.9 0.3 0.00041 18.9 0.3 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Peptidase_A4 PF01828.17 EAQ91856.1 - 1.1e-07 31.6 0.0 1.9e-06 27.5 0.0 2.0 1 1 0 1 1 1 1 Peptidase A4 family DUF1857 PF08982.11 EAQ91857.1 - 1.7e-54 183.7 0.0 1.9e-54 183.5 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1857) CFEM PF05730.11 EAQ91858.1 - 3.5e-06 27.0 10.0 1.2e-05 25.4 10.0 1.8 1 1 0 1 1 1 1 CFEM domain SelP_N PF04592.14 EAQ91860.1 - 2.8 7.3 11.0 4.4 6.6 8.3 2.1 2 0 0 2 2 2 0 Selenoprotein P, N terminal region SNARE_assoc PF09335.11 EAQ91861.1 - 2.1e-10 41.1 0.8 2.1e-10 41.1 0.8 2.7 3 0 0 3 3 3 1 SNARE associated Golgi protein YrhC PF14143.6 EAQ91861.1 - 0.00031 20.8 0.2 0.0007 19.6 0.2 1.6 1 0 0 1 1 1 1 YrhC-like protein DUF1772 PF08592.11 EAQ91861.1 - 0.069 13.5 6.3 0.068 13.5 3.1 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF1772) Wzy_C_2 PF11846.8 EAQ91861.1 - 0.11 12.3 2.6 1.1 9.2 0.4 2.3 2 1 0 2 2 2 0 Virulence factor membrane-bound polymerase, C-terminal DUF3278 PF11683.8 EAQ91861.1 - 0.14 12.2 2.7 0.33 11.0 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3278) PufQ PF05398.11 EAQ91861.1 - 0.64 10.2 3.8 2.5 8.3 1.9 2.6 1 1 1 2 2 2 0 PufQ cytochrome subunit Phage_holin_3_6 PF07332.11 EAQ91861.1 - 3.5 7.7 10.5 0.092 12.8 3.1 2.0 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III CcmD PF04995.14 EAQ91861.1 - 4.6 7.4 11.3 0.82 9.8 3.0 2.9 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) FAD_binding_3 PF01494.19 EAQ91862.1 - 3.3e-16 59.5 0.0 4.5e-16 59.0 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Ank_5 PF13857.6 EAQ91863.1 - 0.00053 20.2 0.1 0.0014 18.8 0.0 1.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAQ91863.1 - 0.039 14.5 0.0 0.26 12.0 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeat Ank PF00023.30 EAQ91863.1 - 0.08 13.4 0.0 3.7 8.2 0.0 2.5 2 0 0 2 2 2 0 Ankyrin repeat COG5 PF10392.9 EAQ91864.1 - 1.6e-42 144.8 2.8 1.6e-42 144.8 2.8 2.2 3 0 0 3 3 3 1 Golgi transport complex subunit 5 LPP PF04728.13 EAQ91864.1 - 0.096 13.1 2.4 0.41 11.1 1.7 2.3 2 0 0 2 2 2 0 Lipoprotein leucine-zipper SRX PF09201.10 EAQ91864.1 - 0.14 11.9 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 SRX, signal recognition particle receptor alpha subunit DUF2434 PF10361.9 EAQ91865.1 - 4.7e-136 452.5 7.2 5.8e-136 452.2 7.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2434) zf-C2H2 PF00096.26 EAQ91866.1 - 0.0001 22.6 14.6 0.024 15.1 4.1 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EAQ91866.1 - 0.00023 21.5 6.1 0.0003 21.1 3.8 2.5 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 EAQ91866.1 - 0.0057 17.4 13.5 0.079 13.8 2.9 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger Colipase PF01114.18 EAQ91868.1 - 0.011 15.4 4.2 0.018 14.7 4.2 1.3 1 0 0 1 1 1 0 Colipase, N-terminal domain Ank_2 PF12796.7 EAQ91869.1 - 4.6e-62 206.6 31.1 1.5e-12 47.9 0.1 9.7 2 2 8 10 10 10 10 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAQ91869.1 - 1.3e-40 137.2 20.1 9.6e-07 29.2 0.0 12.2 7 1 6 13 13 13 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAQ91869.1 - 1.6e-35 117.1 25.1 0.0026 18.1 0.1 18.3 18 1 1 19 19 19 7 Ankyrin repeat Ank_5 PF13857.6 EAQ91869.1 - 4.2e-32 109.8 38.5 0.0043 17.3 0.1 13.4 7 3 6 13 13 13 10 Ankyrin repeats (many copies) Ank PF00023.30 EAQ91869.1 - 5e-24 83.6 62.5 0.00086 19.7 0.2 16.9 18 0 0 18 18 18 8 Ankyrin repeat AAA_22 PF13401.6 EAQ91869.1 - 1.6e-05 25.2 0.0 3.9e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EAQ91869.1 - 0.00033 21.1 0.1 0.002 18.5 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain ERAP1_C PF11838.8 EAQ91869.1 - 0.048 13.2 4.0 1.1 8.8 0.1 3.0 3 0 0 3 3 3 0 ERAP1-like C-terminal domain Unstab_antitox PF09720.10 EAQ91869.1 - 0.068 13.2 1.0 0.2 11.8 0.2 2.3 2 0 0 2 2 2 0 Putative addiction module component NACHT PF05729.12 EAQ91869.1 - 0.089 12.7 0.0 0.38 10.7 0.0 2.0 2 0 0 2 2 2 0 NACHT domain DUF4013 PF13197.6 EAQ91870.1 - 0.034 14.0 3.9 0.054 13.3 3.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4013) Fasciclin PF02469.22 EAQ91872.1 - 3.4e-18 66.1 0.0 1.4e-16 60.9 0.0 2.4 2 0 0 2 2 2 2 Fasciclin domain OsmC PF02566.19 EAQ91874.1 - 4.2e-19 68.9 0.0 5.8e-19 68.4 0.0 1.2 1 0 0 1 1 1 1 OsmC-like protein RTA1 PF04479.13 EAQ91875.1 - 2.9e-63 213.2 10.2 3.5e-63 212.9 10.2 1.1 1 0 0 1 1 1 1 RTA1 like protein DHHC PF01529.20 EAQ91875.1 - 7.9 6.6 6.3 11 6.1 1.6 2.3 2 0 0 2 2 2 0 DHHC palmitoyltransferase Fungal_trans_2 PF11951.8 EAQ91876.1 - 0.0013 17.6 0.0 0.0019 17.1 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Hexapep PF00132.24 EAQ91877.1 - 1.1e-14 53.5 15.9 1.4e-10 40.4 4.5 2.7 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EAQ91877.1 - 1.1e-09 37.9 20.4 6.7e-07 29.0 5.1 2.9 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Mac PF12464.8 EAQ91877.1 - 0.00059 20.0 0.2 0.0011 19.1 0.2 1.4 1 0 0 1 1 1 1 Maltose acetyltransferase XFP_N PF09364.10 EAQ91879.1 - 1.3e-112 376.3 0.1 1e-110 370.0 0.1 2.1 1 1 0 1 1 1 1 XFP N-terminal domain XFP PF03894.15 EAQ91879.1 - 8.5e-65 217.8 0.0 1.2e-64 217.2 0.0 1.2 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase TPP_enzyme_C PF02775.21 EAQ91879.1 - 0.00031 20.6 0.1 0.0086 15.9 0.1 2.4 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Transket_pyr PF02779.24 EAQ91879.1 - 0.18 11.5 0.0 0.34 10.6 0.0 1.4 1 0 0 1 1 1 0 Transketolase, pyrimidine binding domain DUF2939 PF11159.8 EAQ91880.1 - 0.14 12.6 0.1 0.38 11.2 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2939) FAD_binding_4 PF01565.23 EAQ91882.1 - 2e-20 72.9 1.0 2e-20 72.9 1.0 1.9 2 0 0 2 2 2 1 FAD binding domain Cation_ATPase_C PF00689.21 EAQ91884.1 - 1e-48 165.5 0.9 1e-48 165.5 0.9 2.7 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 EAQ91884.1 - 1.3e-34 119.3 0.5 1.3e-34 119.3 0.5 2.6 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 EAQ91884.1 - 1.8e-22 79.2 0.0 7.5e-22 77.2 0.0 2.1 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EAQ91884.1 - 2.7e-19 70.3 0.3 6.1e-19 69.1 0.3 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EAQ91884.1 - 1.5e-07 31.0 0.1 8.2e-07 28.6 0.0 2.3 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EAQ91884.1 - 5.2e-06 26.4 0.9 0.00012 21.9 0.8 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase LptF_LptG PF03739.14 EAQ91884.1 - 0.011 14.7 0.9 0.028 13.3 0.9 1.7 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG RNase_H PF00075.24 EAQ91885.1 - 0.023 14.9 0.0 0.032 14.4 0.0 1.2 1 0 0 1 1 1 0 RNase H RNase_H PF00075.24 EAQ91886.1 - 0.069 13.3 0.1 0.12 12.6 0.1 1.4 1 0 0 1 1 1 0 RNase H SprT-like PF10263.9 EAQ91888.1 - 0.12 12.2 1.0 0.33 10.8 0.5 1.8 2 0 0 2 2 2 0 SprT-like family DUF1996 PF09362.10 EAQ91890.1 - 3.1e-79 266.3 1.7 3.1e-79 266.3 1.7 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1996) UvrB_inter PF17757.1 EAQ91891.1 - 0.063 13.5 0.0 0.1 12.8 0.0 1.3 1 0 0 1 1 1 0 UvrB interaction domain APH PF01636.23 EAQ91892.1 - 1.8e-16 60.8 1.1 7.7e-16 58.7 1.1 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family RVT_2 PF07727.14 EAQ91892.1 - 7.4e-09 35.6 0.0 1.4e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 EAQ91892.1 - 4.2e-08 33.4 0.2 1.4e-07 31.7 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.6 EAQ91892.1 - 1.4e-05 24.8 0.4 3.4e-05 23.6 0.4 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain Choline_kinase PF01633.20 EAQ91892.1 - 0.018 14.6 0.0 0.034 13.7 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase DDE_3 PF13358.6 EAQ91893.1 - 6.1e-13 48.7 0.2 1.2e-12 47.9 0.2 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Flu_PA PF00603.17 EAQ91893.1 - 0.071 11.2 0.1 0.091 10.9 0.1 1.2 1 0 0 1 1 1 0 Influenza RNA-dependent RNA polymerase subunit PA Glyco_hydro_11 PF00457.17 EAQ91894.1 - 6.6e-70 234.4 14.8 7.3e-70 234.2 14.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 GMC_oxred_N PF00732.19 EAQ91895.1 - 1.2e-53 182.4 0.0 1.7e-53 182.0 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EAQ91895.1 - 1.7e-29 103.2 0.1 2.9e-29 102.4 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 EAQ91895.1 - 5.7e-06 25.6 0.0 1e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 EAQ91895.1 - 4e-05 23.0 0.0 0.00056 19.2 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EAQ91895.1 - 5.7e-05 22.9 0.0 0.0025 17.4 0.0 2.9 4 0 0 4 4 4 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EAQ91895.1 - 0.00032 20.0 0.1 0.5 9.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EAQ91895.1 - 0.00077 19.6 0.1 0.003 17.7 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EAQ91895.1 - 0.0027 16.9 0.1 0.017 14.2 0.1 2.0 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 EAQ91895.1 - 0.036 12.8 0.0 0.71 8.5 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein GIDA PF01134.22 EAQ91895.1 - 0.09 11.8 0.0 8.1 5.4 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A EHN PF06441.12 EAQ91895.1 - 0.19 12.1 1.5 1.7 9.0 0.0 2.9 3 1 0 3 3 3 0 Epoxide hydrolase N terminus Photo_RC PF00124.19 EAQ91896.1 - 0.095 11.9 4.7 0.022 14.0 1.3 1.7 2 0 0 2 2 2 0 Photosynthetic reaction centre protein GFA PF04828.14 EAQ91897.1 - 8.9e-16 58.0 0.2 1.5e-15 57.3 0.2 1.4 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Nudix_N_2 PF14803.6 EAQ91897.1 - 0.0041 17.0 0.3 0.0041 17.0 0.3 2.0 3 0 0 3 3 3 1 Nudix N-terminal 2-Hacid_dh_C PF02826.19 EAQ91898.1 - 2.6e-41 140.9 0.1 1.3e-26 93.0 0.0 2.5 3 0 0 3 3 3 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain XdhC_C PF13478.6 EAQ91898.1 - 0.0042 17.6 0.0 0.0098 16.4 0.0 1.6 1 1 0 1 1 1 1 XdhC Rossmann domain F420_oxidored PF03807.17 EAQ91898.1 - 0.016 15.8 0.0 0.17 12.5 0.0 2.6 3 1 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent Drf_DAD PF06345.11 EAQ91898.1 - 0.11 12.5 0.2 0.29 11.2 0.2 1.7 1 0 0 1 1 1 0 DRF Autoregulatory Domain NAD_binding_8 PF13450.6 EAQ91899.1 - 0.0075 16.5 0.1 0.013 15.7 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Herpes_ori_bp PF02399.15 EAQ91901.1 - 0.056 11.5 0.1 0.082 10.9 0.1 1.1 1 0 0 1 1 1 0 Origin of replication binding protein Cwf_Cwc_15 PF04889.12 EAQ91901.1 - 2.2 7.9 5.0 3.6 7.2 5.0 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Pyr_redox_2 PF07992.14 EAQ91903.1 - 3.9e-48 164.2 0.0 5.1e-48 163.8 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EAQ91903.1 - 7.2e-27 93.8 0.0 1.5e-26 92.8 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 EAQ91903.1 - 3.1e-20 72.5 0.1 1.1e-19 70.8 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EAQ91903.1 - 2.9e-06 26.8 0.0 4.2e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 EAQ91903.1 - 0.00068 19.6 0.1 0.0019 18.1 0.0 1.7 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_8 PF13450.6 EAQ91903.1 - 0.001 19.2 0.5 0.19 12.0 0.1 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 EAQ91903.1 - 0.003 16.9 0.0 0.0051 16.1 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 EAQ91903.1 - 0.0061 15.3 0.3 0.18 10.4 0.1 2.7 2 1 1 3 3 3 1 HI0933-like protein UDPG_MGDP_dh_N PF03721.14 EAQ91903.1 - 0.027 14.1 0.0 0.042 13.4 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain GIDA PF01134.22 EAQ91903.1 - 0.043 12.9 0.1 0.29 10.1 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_7 PF13241.6 EAQ91903.1 - 0.052 14.0 0.0 0.11 13.0 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding TrkA_N PF02254.18 EAQ91903.1 - 0.098 12.9 0.0 0.38 11.0 0.1 1.9 2 0 0 2 2 2 0 TrkA-N domain 2-Hacid_dh_C PF02826.19 EAQ91903.1 - 0.1 12.0 0.0 0.25 10.7 0.0 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 EAQ91903.1 - 0.17 10.9 3.9 1.4 7.9 0.1 3.1 2 1 2 4 4 4 0 FAD binding domain DapB_N PF01113.20 EAQ91903.1 - 0.17 12.0 0.3 6.8 6.8 0.1 2.4 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Dimer_Tnp_hAT PF05699.14 EAQ91904.1 - 1.1e-16 60.4 0.1 1.9e-16 59.6 0.1 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Glyoxalase PF00903.25 EAQ91906.1 - 0.0035 17.5 0.0 0.0042 17.3 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DHFR_2 PF06442.11 EAQ91906.1 - 0.037 13.9 0.5 0.49 10.3 0.0 2.3 2 1 0 2 2 2 0 R67 dihydrofolate reductase SnoaL_4 PF13577.6 EAQ91907.1 - 9.7e-16 58.1 0.0 1.5e-15 57.4 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain AA_permease PF00324.21 EAQ91908.1 - 4.5e-65 220.1 37.0 7.8e-61 206.1 21.9 2.0 1 1 1 2 2 2 2 Amino acid permease AA_permease_2 PF13520.6 EAQ91908.1 - 1.2e-18 67.1 25.2 1.2e-18 67.1 25.2 1.4 1 1 0 1 1 1 1 Amino acid permease Sugar_tr PF00083.24 EAQ91909.1 - 1.1e-89 301.4 19.2 1.3e-89 301.2 19.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EAQ91909.1 - 3e-31 108.6 43.3 5.7e-25 88.0 30.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily BTB PF00651.31 EAQ91910.1 - 1.1e-15 57.8 0.0 2.1e-15 56.9 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Mid2 PF04478.12 EAQ91910.1 - 0.17 11.7 0.1 0.28 11.0 0.1 1.3 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor GFA PF04828.14 EAQ91911.1 - 3e-10 40.3 1.6 3e-10 40.3 1.6 1.8 2 1 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Pam17 PF08566.10 EAQ91913.1 - 0.16 11.8 0.4 0.26 11.1 0.4 1.4 1 0 0 1 1 1 0 Mitochondrial import protein Pam17 Ank_2 PF12796.7 EAQ91914.1 - 6e-12 46.0 0.1 1e-05 26.0 0.0 3.3 3 1 1 4 4 4 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAQ91914.1 - 3e-10 40.4 0.0 1.9e-05 25.1 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EAQ91914.1 - 0.0005 20.4 0.5 7.2 7.3 0.1 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 EAQ91914.1 - 0.0014 19.0 0.6 3.5 8.5 0.0 4.8 5 0 0 5 5 5 1 Ankyrin repeat Ank_5 PF13857.6 EAQ91914.1 - 0.017 15.5 2.2 5.3 7.5 0.1 3.5 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Clr5 PF14420.6 EAQ91914.1 - 0.089 13.0 0.0 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 Clr5 domain RelA_SpoT PF04607.17 EAQ91917.1 - 6.4e-12 45.8 1.1 7.6e-11 42.3 1.1 2.5 1 1 0 1 1 1 1 Region found in RelA / SpoT proteins APH PF01636.23 EAQ91918.1 - 2.8e-13 50.4 0.0 4.7e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EAQ91918.1 - 0.00074 19.2 0.0 0.0012 18.5 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Methyltransf_2 PF00891.18 EAQ91919.1 - 4.8e-08 32.6 0.0 7.7e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Glyco_transf_20 PF00982.21 EAQ91920.1 - 1.1e-146 489.3 0.0 1.4e-146 488.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 EAQ91920.1 - 3.1e-71 239.2 0.0 5.6e-71 238.4 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase DUF1819 PF08849.11 EAQ91920.1 - 0.11 12.3 0.1 0.21 11.4 0.1 1.4 1 0 0 1 1 1 0 Putative inner membrane protein (DUF1819) Cys_Met_Meta_PP PF01053.20 EAQ91923.1 - 3.4e-33 114.7 0.0 5e-33 114.2 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 EAQ91923.1 - 0.083 12.0 0.0 0.19 10.9 0.0 1.7 1 1 0 1 1 1 0 Aminotransferase class I and II CheW PF01584.19 EAQ91923.1 - 0.13 11.9 0.2 3.6 7.2 0.1 2.4 2 0 0 2 2 2 0 CheW-like domain DZR PF12773.7 EAQ91926.1 - 0.016 15.3 1.5 0.031 14.3 1.5 1.5 1 0 0 1 1 1 0 Double zinc ribbon zf-NADH-PPase PF09297.11 EAQ91926.1 - 0.016 14.9 4.5 2 8.1 0.6 3.2 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain zinc_ribbon_2 PF13240.6 EAQ91926.1 - 0.032 13.9 4.8 1.5 8.7 0.3 2.4 2 0 0 2 2 2 0 zinc-ribbon domain DUF2321 PF10083.9 EAQ91926.1 - 0.22 11.1 0.5 0.32 10.6 0.5 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) Nudix_N_2 PF14803.6 EAQ91926.1 - 0.41 10.6 4.5 4.3 7.4 0.7 2.4 2 0 0 2 2 2 0 Nudix N-terminal zf-ribbon_3 PF13248.6 EAQ91926.1 - 1.7 8.2 8.3 15 5.2 8.3 2.3 1 1 0 1 1 1 0 zinc-ribbon domain AAA_16 PF13191.6 EAQ91927.1 - 8e-07 29.6 0.1 4.5e-06 27.1 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain Ank_2 PF12796.7 EAQ91927.1 - 2.3e-06 28.1 0.0 2.4e-05 24.8 0.0 2.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAQ91927.1 - 0.0023 18.2 0.2 2.2 8.7 0.0 3.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAQ91927.1 - 0.0028 18.2 0.1 0.019 15.6 0.1 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) TRPM_tetra PF16519.5 EAQ91927.1 - 0.0083 16.2 0.5 0.018 15.1 0.5 1.5 1 0 0 1 1 1 1 Tetramerisation domain of TRPM Ank_3 PF13606.6 EAQ91927.1 - 0.045 14.3 1.9 3.6 8.5 0.2 4.0 4 0 0 4 4 4 0 Ankyrin repeat AAA_14 PF13173.6 EAQ91927.1 - 0.068 13.2 0.0 8.4 6.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain Ank PF00023.30 EAQ91927.1 - 0.83 10.2 7.8 1.4 9.5 0.8 4.2 4 0 0 4 4 4 0 Ankyrin repeat Ank_2 PF12796.7 EAQ91929.1 - 1.9e-48 162.9 0.0 1.5e-16 60.7 0.0 6.0 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAQ91929.1 - 2.6e-35 116.4 0.0 0.00035 20.8 0.0 9.9 9 0 0 9 9 9 7 Ankyrin repeat Ank_4 PF13637.6 EAQ91929.1 - 1.2e-34 118.2 0.0 1.1e-08 35.4 0.0 6.9 4 1 2 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAQ91929.1 - 6.5e-33 112.4 3.4 2e-05 24.8 0.0 7.5 2 2 5 7 7 7 5 Ankyrin repeats (many copies) Ank PF00023.30 EAQ91929.1 - 1.7e-25 88.3 0.7 0.021 15.3 0.0 10.0 10 0 0 10 10 9 6 Ankyrin repeat NACHT PF05729.12 EAQ91929.1 - 1e-10 41.8 0.2 8e-09 35.6 0.0 2.9 3 0 0 3 3 3 1 NACHT domain Arf PF00025.21 EAQ91929.1 - 6.9e-07 28.9 0.0 1.5e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_16 PF13191.6 EAQ91929.1 - 1.6e-06 28.6 0.0 0.0017 18.8 0.0 3.4 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 EAQ91929.1 - 0.00042 20.7 0.0 0.0018 18.7 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) KAP_NTPase PF07693.14 EAQ91929.1 - 0.0046 16.2 0.0 0.015 14.5 0.0 1.8 2 0 0 2 2 2 1 KAP family P-loop domain AAA_18 PF13238.6 EAQ91929.1 - 0.0058 17.2 0.0 0.11 13.0 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EAQ91929.1 - 0.0059 16.9 0.3 0.13 12.6 0.0 3.3 5 0 0 5 5 3 1 AAA domain RNA_helicase PF00910.22 EAQ91929.1 - 0.024 15.0 0.0 0.12 12.8 0.0 2.2 2 0 0 2 2 2 0 RNA helicase ABC_tran PF00005.27 EAQ91929.1 - 0.051 14.1 0.0 20 5.7 0.0 2.7 2 0 0 2 2 2 0 ABC transporter AAA_25 PF13481.6 EAQ91929.1 - 0.055 13.0 0.0 0.5 9.9 0.0 2.7 3 0 0 3 3 3 0 AAA domain APS_kinase PF01583.20 EAQ91929.1 - 0.062 13.2 0.0 0.88 9.5 0.0 2.6 2 0 0 2 2 2 0 Adenylylsulphate kinase UPF0137 PF03677.13 EAQ91929.1 - 0.12 12.2 0.1 0.2 11.5 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) ATPase PF06745.13 EAQ91929.1 - 0.13 11.6 0.0 2.2 7.6 0.0 2.3 2 0 0 2 2 2 0 KaiC IstB_IS21 PF01695.17 EAQ91929.1 - 0.14 11.9 0.0 0.39 10.4 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein Rad17 PF03215.15 EAQ91929.1 - 0.18 11.7 0.0 0.52 10.2 0.0 1.7 2 0 0 2 2 1 0 Rad17 P-loop domain RsgA_GTPase PF03193.16 EAQ91929.1 - 0.23 11.4 0.4 13 5.6 0.0 3.1 4 0 0 4 4 3 0 RsgA GTPase Hemerythrin PF01814.23 EAQ91931.1 - 0.01 16.4 0.2 0.016 15.8 0.2 1.2 1 0 0 1 1 1 0 Hemerythrin HHE cation binding domain RVT_2 PF07727.14 EAQ91932.1 - 0.00027 20.7 0.0 0.00047 19.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Hemerythrin PF01814.23 EAQ91933.1 - 0.00086 19.9 1.7 0.0017 19.0 1.1 1.5 1 1 0 1 1 1 1 Hemerythrin HHE cation binding domain DUF1722 PF08349.11 EAQ91933.1 - 0.02 15.2 0.1 0.12 12.7 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) PTR2 PF00854.21 EAQ91934.1 - 1.3e-30 106.6 0.0 2.7e-30 105.5 0.0 1.4 1 1 0 1 1 1 1 POT family MFS_1 PF07690.16 EAQ91934.1 - 3.7e-06 26.1 6.8 0.0093 14.9 4.4 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily ABC_export PF16962.5 EAQ91934.1 - 0.021 13.3 0.6 0.021 13.3 0.6 1.8 2 0 0 2 2 2 0 Putative ABC exporter Nuc_H_symport PF03825.16 EAQ91934.1 - 0.036 13.1 0.1 0.036 13.1 0.1 1.9 2 0 0 2 2 2 0 Nucleoside H+ symporter GPI2 PF06432.11 EAQ91934.1 - 0.13 11.7 0.7 0.25 10.8 0.1 1.7 2 0 0 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase UPF0016 PF01169.19 EAQ91934.1 - 0.2 12.0 3.8 3.5 8.0 0.0 3.6 3 1 1 4 4 4 0 Uncharacterized protein family UPF0016 Dmrt1 PF12374.8 EAQ91935.1 - 0.1 13.1 6.8 0.13 12.8 5.7 1.8 2 1 0 2 2 2 0 Double-sex mab3 related transcription factor 1 Methyltransf_31 PF13847.6 EAQ91936.1 - 7.2e-20 71.3 0.0 1.5e-19 70.3 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAQ91936.1 - 8.1e-13 48.9 0.0 3e-11 43.9 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EAQ91936.1 - 1.5e-09 38.5 0.0 3.9e-09 37.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EAQ91936.1 - 3.4e-09 36.8 0.0 5.5e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EAQ91936.1 - 1.3e-08 35.4 0.0 4.2e-08 33.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.17 EAQ91936.1 - 1.6e-05 24.5 0.0 3.7e-05 23.3 0.0 1.6 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.14 EAQ91936.1 - 2.4e-05 24.0 0.0 5.9e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.19 EAQ91936.1 - 3.7e-05 23.9 0.0 4.9e-05 23.5 0.0 1.3 1 1 0 1 1 1 1 FtsJ-like methyltransferase Ubie_methyltran PF01209.18 EAQ91936.1 - 0.00036 20.0 0.0 0.001 18.4 0.0 1.7 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 EAQ91936.1 - 0.00077 18.8 0.0 0.0011 18.3 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_32 PF13679.6 EAQ91936.1 - 0.0015 18.5 0.0 0.0028 17.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EAQ91936.1 - 0.0016 17.8 0.0 0.0026 17.1 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.7 EAQ91936.1 - 0.0073 16.2 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EAQ91936.1 - 0.052 13.3 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FmrO PF07091.11 EAQ91936.1 - 0.19 11.2 0.0 0.33 10.5 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Ferric_reduct PF01794.19 EAQ91937.1 - 1.2e-19 70.6 18.4 4.7e-19 68.7 18.4 2.1 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 EAQ91937.1 - 1.1e-06 28.8 0.1 0.0062 16.7 0.0 2.8 2 1 1 3 3 3 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EAQ91937.1 - 0.00051 20.1 0.1 0.045 13.8 0.1 2.6 1 1 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 EAQ91937.1 - 0.12 13.0 0.1 0.91 10.2 0.1 2.2 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain DUF4293 PF14126.6 EAQ91937.1 - 0.18 12.0 6.0 0.48 10.7 5.8 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4293) ATP-grasp_4 PF13535.6 EAQ91938.1 - 7.7e-11 41.8 0.0 1.4e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 EAQ91938.1 - 0.0013 18.3 0.0 0.0026 17.3 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus MULE PF10551.9 EAQ91940.1 - 1.5e-24 86.2 0.4 2.8e-24 85.4 0.4 1.5 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.18 EAQ91940.1 - 6.9e-08 31.7 0.2 9.1e-07 28.1 0.0 2.2 2 0 0 2 2 2 1 Transposase, Mutator family RBR PF17208.3 EAQ91940.1 - 0.37 11.5 12.1 2.1 9.1 12.1 2.3 1 0 0 1 1 1 0 RNA binding Region RT_RNaseH PF17917.1 EAQ91941.1 - 1.7e-39 134.3 0.0 4.4e-39 133.0 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 EAQ91941.1 - 6.1e-35 119.3 0.0 1.4e-34 118.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 EAQ91941.1 - 1e-13 51.5 0.1 2.7e-13 50.2 0.1 1.8 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 EAQ91941.1 - 6.1e-13 48.7 0.0 1.2e-12 47.7 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain Chromo PF00385.24 EAQ91941.1 - 3.4e-11 42.9 0.1 3.4e-11 42.9 0.1 1.9 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 EAQ91941.1 - 0.00052 20.2 0.0 0.0012 19.0 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger NEXCaM_BD PF16644.5 EAQ91941.1 - 0.046 14.0 0.4 0.1 12.9 0.4 1.5 1 0 0 1 1 1 0 Regulatory region of Na+/H+ exchanger NHE binds to calmodulin PALP PF00291.25 EAQ91942.1 - 7.7e-11 41.9 0.0 1.3e-09 37.9 0.0 2.4 1 1 1 2 2 2 1 Pyridoxal-phosphate dependent enzyme Mito_carr PF00153.27 EAQ91943.1 - 1.8e-49 165.6 5.8 1.4e-20 73.0 0.3 4.0 4 0 0 4 4 4 4 Mitochondrial carrier protein DUF2370 PF10176.9 EAQ91945.1 - 2.2e-55 187.7 1.0 4.3e-30 105.0 0.1 2.9 1 1 1 2 2 2 2 Protein of unknown function (DUF2370) CD99L2 PF12301.8 EAQ91945.1 - 2.8 8.2 6.0 0.56 10.5 2.1 1.8 2 0 0 2 2 2 0 CD99 antigen like protein 2 PCMT PF01135.19 EAQ91946.1 - 8.5e-53 179.2 0.0 1e-52 179.0 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 EAQ91946.1 - 3.4e-05 23.7 0.0 5.5e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 EAQ91946.1 - 0.00022 21.2 0.0 0.00033 20.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAQ91946.1 - 0.002 18.8 0.0 0.0036 18.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EAQ91946.1 - 0.0029 17.5 0.0 0.0035 17.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EAQ91946.1 - 0.017 15.7 0.0 0.028 15.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 EAQ91946.1 - 0.039 13.5 0.0 0.065 12.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain CHASE2 PF05226.11 EAQ91946.1 - 0.1 12.3 0.2 6.4 6.4 0.0 2.2 2 0 0 2 2 2 0 CHASE2 domain Ubie_methyltran PF01209.18 EAQ91946.1 - 0.18 11.1 0.0 0.29 10.4 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family FAD_binding_3 PF01494.19 EAQ91947.1 - 1.4e-10 41.0 0.0 2.3e-10 40.3 0.0 1.3 1 1 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 EAQ91947.1 - 2.1e-05 25.0 0.0 8.1e-05 23.1 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase CoA_transf_3 PF02515.17 EAQ91947.1 - 0.00012 21.3 0.3 0.00098 18.3 0.2 2.0 2 0 0 2 2 2 1 CoA-transferase family III NAD_binding_8 PF13450.6 EAQ91947.1 - 0.00014 22.1 0.1 0.00035 20.7 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EAQ91947.1 - 0.00014 21.6 0.3 0.00027 20.6 0.3 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EAQ91947.1 - 0.00018 20.8 0.1 0.0003 20.1 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EAQ91947.1 - 0.0012 18.0 0.1 0.0019 17.4 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 EAQ91947.1 - 0.0017 17.7 0.3 0.0028 17.1 0.3 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 EAQ91947.1 - 0.0084 15.2 0.9 0.018 14.2 0.6 1.6 1 1 1 2 2 2 1 Glucose inhibited division protein A ApbA PF02558.16 EAQ91947.1 - 0.0091 15.6 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA AlaDh_PNT_C PF01262.21 EAQ91947.1 - 0.011 15.1 0.2 0.017 14.4 0.2 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 EAQ91947.1 - 0.015 14.6 0.0 0.025 13.8 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EAQ91947.1 - 0.027 13.7 0.0 0.042 13.1 0.0 1.2 1 0 0 1 1 1 0 Thi4 family Pex14_N PF04695.13 EAQ91947.1 - 0.8 10.3 5.0 1.5 9.5 5.0 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Fungal_trans PF04082.18 EAQ91948.1 - 4.7e-14 52.1 0.2 9.1e-14 51.1 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EAQ91948.1 - 2.2e-10 40.5 10.6 4.3e-10 39.5 10.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RVT_1 PF00078.27 EAQ91949.1 - 1.1e-35 123.2 0.0 1.6e-35 122.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_2 PF07727.14 EAQ91950.1 - 1.1e-48 166.0 0.0 1.8e-48 165.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 EAQ91950.1 - 1.9e-12 47.4 0.0 5.7e-12 45.9 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.6 EAQ91950.1 - 0.027 14.3 0.1 0.066 13.1 0.1 1.6 1 0 0 1 1 1 0 GAG-pre-integrase domain HTH_AsnC-type PF13404.6 EAQ91950.1 - 0.18 11.7 0.0 0.58 10.0 0.0 1.9 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain DUF2841 PF11001.8 EAQ91951.1 - 3e-27 95.1 0.1 4.1e-27 94.7 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) EIN3 PF04873.13 EAQ91951.1 - 0.027 13.8 0.0 0.034 13.5 0.0 1.1 1 0 0 1 1 1 0 Ethylene insensitive 3 Dimer_Tnp_hAT PF05699.14 EAQ91955.1 - 1.2e-18 66.6 0.2 2.1e-18 65.9 0.2 1.3 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region CVNH PF08881.10 EAQ91958.1 - 2.1e-11 44.4 3.7 9.9e-11 42.2 3.4 1.9 1 1 1 2 2 2 2 CVNH domain Filament PF00038.21 EAQ91960.1 - 0.0059 16.2 14.6 0.0059 16.2 14.6 7.9 2 2 5 7 7 7 4 Intermediate filament protein Spc7 PF08317.11 EAQ91960.1 - 0.018 13.9 117.2 0.23 10.3 7.2 7.2 2 2 4 7 7 7 0 Spc7 kinetochore protein DUF2663 PF10864.8 EAQ91960.1 - 0.13 12.6 0.9 1.6 9.2 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2663) ATG16 PF08614.11 EAQ91960.1 - 0.17 12.1 143.1 0.49 10.6 14.9 8.0 2 2 6 8 8 8 0 Autophagy protein 16 (ATG16) Fez1 PF06818.15 EAQ91960.1 - 4.3 7.8 109.3 0.3 11.5 23.8 6.8 1 1 4 5 5 5 0 Fez1 DAO PF01266.24 EAQ91961.1 - 1.3e-38 133.5 4.1 1.6e-38 133.2 4.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Rieske PF00355.26 EAQ91961.1 - 1.2e-11 44.4 0.1 3.8e-11 42.8 0.1 1.8 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain NAD_binding_8 PF13450.6 EAQ91961.1 - 1.4e-06 28.4 0.8 3.6e-06 27.1 0.8 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 EAQ91961.1 - 2.8e-05 23.7 1.4 0.15 11.4 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EAQ91961.1 - 0.00051 19.4 0.0 0.00091 18.5 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EAQ91961.1 - 0.00073 18.7 0.5 0.0012 18.0 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 EAQ91961.1 - 0.0069 16.9 0.2 0.02 15.5 0.2 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EAQ91961.1 - 0.016 13.9 0.1 0.022 13.4 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.19 EAQ91961.1 - 0.034 13.4 3.2 0.092 12.0 3.2 2.0 1 1 0 1 1 1 0 FAD binding domain 3HCDH_N PF02737.18 EAQ91961.1 - 0.053 13.4 0.3 0.1 12.5 0.3 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.6 EAQ91961.1 - 0.1 11.9 0.0 0.2 10.8 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EAQ91961.1 - 0.11 11.6 1.2 0.19 10.8 0.5 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A Amino_oxidase PF01593.24 EAQ91961.1 - 0.11 11.7 0.5 0.2 10.9 0.2 1.5 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.12 EAQ91961.1 - 0.12 11.4 0.4 0.59 9.1 0.1 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein adh_short_C2 PF13561.6 EAQ91962.1 - 1.9e-32 112.7 2.3 2.5e-19 69.8 0.1 2.4 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EAQ91962.1 - 3.2e-32 111.6 5.8 1.1e-20 73.9 0.3 2.1 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 EAQ91962.1 - 9e-08 32.2 0.5 9e-08 32.2 0.5 1.9 2 0 0 2 2 2 1 KR domain RNase_H PF00075.24 EAQ91963.1 - 6.7e-21 75.0 0.0 1.8e-20 73.6 0.0 1.8 2 0 0 2 2 2 1 RNase H zf-MYND PF01753.18 EAQ91963.1 - 3.3e-08 33.5 6.0 6e-08 32.7 6.0 1.5 1 0 0 1 1 1 1 MYND finger RVT_3 PF13456.6 EAQ91963.1 - 0.019 14.8 0.0 0.4 10.5 0.0 2.5 1 1 0 1 1 1 0 Reverse transcriptase-like RTA1 PF04479.13 EAQ91964.1 - 7.2e-18 64.9 0.2 8.4e-18 64.7 0.2 1.1 1 0 0 1 1 1 1 RTA1 like protein Exo_endo_phos_2 PF14529.6 EAQ91966.1 - 3e-27 94.8 0.0 1.6e-26 92.4 0.0 2.0 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 EAQ91966.1 - 0.00011 21.8 0.1 0.00015 21.4 0.1 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-CCHC PF00098.23 EAQ91966.1 - 0.00047 20.1 3.1 0.0011 18.9 3.1 1.6 1 0 0 1 1 1 1 Zinc knuckle Dimer_Tnp_hAT PF05699.14 EAQ91969.1 - 4.8e-18 64.7 0.2 1e-17 63.6 0.2 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4174 PF13778.6 EAQ91970.1 - 0.019 15.4 0.0 0.041 14.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4174) 7tm_4 PF13853.6 EAQ91970.1 - 0.053 13.3 0.0 0.087 12.5 0.0 1.2 1 0 0 1 1 1 0 Olfactory receptor DUF4413 PF14372.6 EAQ91970.1 - 0.12 12.8 0.0 0.31 11.4 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4413) HTH_Tnp_Tc5 PF03221.16 EAQ91971.1 - 3e-13 49.6 0.1 6.7e-13 48.5 0.1 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_1 PF03184.19 EAQ91971.1 - 4e-12 46.1 0.1 6.1e-11 42.3 0.0 2.6 3 0 0 3 3 3 1 DDE superfamily endonuclease DUF1192 PF06698.11 EAQ91971.1 - 0.15 12.2 0.7 0.38 10.8 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) MULE PF10551.9 EAQ91972.1 - 1.2e-11 44.9 2.8 2.2e-11 44.0 0.5 2.5 1 1 1 2 2 2 1 MULE transposase domain FAR1 PF03101.15 EAQ91972.1 - 0.0068 17.1 0.3 0.017 15.8 0.3 1.7 1 0 0 1 1 1 1 FAR1 DNA-binding domain p450 PF00067.22 EAQ91973.1 - 2.1e-43 148.7 0.0 2.7e-43 148.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 RT_RNaseH PF17917.1 EAQ91974.1 - 7.6e-32 109.7 0.0 1.9e-31 108.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 EAQ91974.1 - 3.7e-31 107.1 0.0 8.1e-31 106.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 EAQ91974.1 - 1.6e-17 63.8 0.0 1.6e-16 60.5 0.0 2.4 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 EAQ91974.1 - 3.2e-14 52.8 0.0 6.4e-14 51.8 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 EAQ91974.1 - 5e-13 49.3 0.0 1.7e-12 47.6 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 EAQ91974.1 - 2.9e-05 23.9 0.7 0.0001 22.1 0.3 2.3 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain zf-CCHC PF00098.23 EAQ91974.1 - 7.8e-05 22.6 2.5 0.00025 21.0 2.5 1.9 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 EAQ91974.1 - 0.0074 16.0 2.0 0.019 14.7 2.0 1.7 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger Retrotrans_gag PF03732.17 EAQ91974.1 - 0.035 14.4 0.1 0.035 14.4 0.1 3.6 3 0 0 3 3 3 0 Retrotransposon gag protein DUF1257 PF06868.11 EAQ91974.1 - 0.058 13.6 3.3 0.69 10.2 0.2 3.2 2 1 1 3 3 2 0 Protein of unknown function (DUF1257) YabA PF06156.13 EAQ91974.1 - 0.069 13.8 4.6 0.25 12.0 3.6 2.4 2 0 0 2 2 2 0 Initiation control protein YabA RVP_2 PF08284.11 EAQ91974.1 - 0.07 12.9 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease MLVIN_C PF18697.1 EAQ91974.1 - 0.11 12.7 0.0 0.36 10.9 0.0 2.0 1 0 0 1 1 1 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain DUF5387 PF17361.2 EAQ91974.1 - 0.12 12.0 1.7 2.3 7.8 0.0 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5387) ZapB PF06005.12 EAQ91974.1 - 0.48 10.9 4.6 2.8 8.5 4.6 2.4 1 0 0 1 1 1 0 Cell division protein ZapB bZIP_1 PF00170.21 EAQ91974.1 - 3.3 7.9 7.1 4.3 7.5 0.1 3.3 2 1 1 3 3 3 0 bZIP transcription factor TPR_MLP1_2 PF07926.12 EAQ91974.1 - 5.3 7.1 8.7 5.2 7.1 0.1 2.8 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein SlyX PF04102.12 EAQ91974.1 - 5.4 7.7 7.6 31 5.3 3.9 3.7 3 1 0 3 3 2 0 SlyX Exo_endo_phos_2 PF14529.6 EAQ91975.1 - 1.2e-08 34.8 1.4 1e-07 31.8 1.0 2.8 3 0 0 3 3 3 1 Endonuclease-reverse transcriptase zf-CCHC PF00098.23 EAQ91975.1 - 0.00087 19.3 1.7 0.00087 19.3 1.7 2.9 3 0 0 3 3 3 1 Zinc knuckle SlyX PF04102.12 EAQ91975.1 - 0.0012 19.4 5.5 0.027 15.1 5.5 2.7 1 1 0 1 1 1 1 SlyX USP8_interact PF08941.10 EAQ91975.1 - 0.018 14.9 0.1 0.055 13.3 0.1 1.9 1 0 0 1 1 1 0 USP8 interacting PKcGMP_CC PF16808.5 EAQ91975.1 - 0.047 13.5 0.3 0.12 12.2 0.3 1.7 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase SEEK1 PF15357.6 EAQ91975.1 - 0.085 13.0 0.6 0.2 11.8 0.6 1.6 1 0 0 1 1 1 0 Psoriasis susceptibility 1 candidate 1 Herpes_pp85 PF04637.12 EAQ91975.1 - 0.38 9.1 3.3 0.59 8.5 3.3 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) HalX PF08663.10 EAQ91975.1 - 0.57 10.5 3.3 4.2 7.8 2.7 2.6 2 0 0 2 2 2 0 HalX domain Syntaxin-6_N PF09177.11 EAQ91975.1 - 0.9 10.1 6.0 1.8 9.2 0.2 3.4 3 1 0 3 3 3 0 Syntaxin 6, N-terminal Filament PF00038.21 EAQ91975.1 - 2.1 7.8 6.1 0.37 10.3 1.8 1.8 2 0 0 2 2 2 0 Intermediate filament protein ADIP PF11559.8 EAQ91975.1 - 8.6 6.4 7.5 0.71 10.0 2.1 1.9 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Mid2 PF04478.12 EAQ91977.1 - 0.1 12.4 0.2 0.22 11.4 0.2 1.5 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Tyrosinase PF00264.20 EAQ91978.1 - 3.3e-12 47.2 0.0 9.7e-12 45.6 0.0 1.7 1 1 1 2 2 2 1 Common central domain of tyrosinase HET PF06985.11 EAQ91979.1 - 5.2e-30 104.7 0.2 1.1e-29 103.6 0.2 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Peptidase_S8 PF00082.22 EAQ91980.1 - 7.3e-06 25.5 0.6 1e-05 24.9 0.6 1.2 1 0 0 1 1 1 1 Subtilase family rve PF00665.26 EAQ91982.1 - 5.6e-09 36.2 0.0 1.5e-08 34.9 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.6 EAQ91982.1 - 9.8e-07 28.5 0.0 3.2e-06 26.9 0.0 1.9 2 0 0 2 2 2 1 GAG-pre-integrase domain RVT_1 PF00078.27 EAQ91984.1 - 2.4e-35 122.1 0.0 3.9e-35 121.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 EAQ91984.1 - 2.6e-07 30.5 0.0 7.9e-07 28.9 0.0 1.9 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RVT_3 PF13456.6 EAQ91984.1 - 0.013 15.3 0.0 0.032 14.0 0.0 1.6 1 0 0 1 1 1 0 Reverse transcriptase-like zf-RVT PF13966.6 EAQ91984.1 - 0.015 16.0 1.5 0.069 13.9 0.2 2.8 2 0 0 2 2 2 0 zinc-binding in reverse transcriptase Exo_endo_phos PF03372.23 EAQ91984.1 - 0.017 14.7 0.0 0.04 13.4 0.0 1.7 1 1 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family GCSF PF16647.5 EAQ91984.1 - 0.085 12.7 0.1 0.22 11.4 0.1 1.7 1 0 0 1 1 1 0 Granulocyte colony-stimulating factor DJ-1_PfpI PF01965.24 EAQ91985.1 - 1.8e-13 50.6 0.0 2.4e-13 50.2 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family NACHT PF05729.12 EAQ91986.1 - 1.9e-07 31.1 0.0 4.7e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 NACHT domain PGAP1 PF07819.13 EAQ91986.1 - 1.5e-06 28.1 0.0 3.9e-06 26.7 0.0 1.6 1 1 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.14 EAQ91986.1 - 1.7e-06 27.7 0.0 3.3e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 EAQ91986.1 - 7.1e-06 26.8 3.4 1.1e-05 26.2 0.4 2.7 2 1 0 2 2 2 1 Alpha/beta hydrolase family WD40_like PF17005.5 EAQ91986.1 - 0.00045 19.6 0.0 1.2 8.4 0.0 2.9 3 0 0 3 3 3 2 WD40-like domain AAA_16 PF13191.6 EAQ91986.1 - 0.0031 17.9 0.4 0.04 14.3 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain Frtz PF11768.8 EAQ91986.1 - 0.0054 15.1 0.0 0.0091 14.4 0.0 1.3 1 0 0 1 1 1 1 WD repeat-containing and planar cell polarity effector protein Fritz DUF2075 PF09848.9 EAQ91986.1 - 0.0078 15.5 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Thioesterase PF00975.20 EAQ91986.1 - 0.03 14.4 0.0 0.058 13.5 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain Lipase_3 PF01764.25 EAQ91986.1 - 0.062 13.2 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_1 PF00561.20 EAQ91986.1 - 0.074 12.7 0.5 0.21 11.2 0.5 1.7 1 1 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EAQ91986.1 - 0.1 11.8 0.0 0.24 10.6 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 AAA_22 PF13401.6 EAQ91986.1 - 0.13 12.5 0.0 2.7 8.2 0.0 2.7 3 0 0 3 3 3 0 AAA domain NB-ARC PF00931.22 EAQ91986.1 - 0.16 11.1 0.0 0.41 9.8 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain AAA_5 PF07728.14 EAQ91986.1 - 0.19 11.8 0.0 7 6.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Fructosamin_kin PF03881.14 EAQ91987.1 - 2.2e-37 128.8 0.0 3e-37 128.4 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 EAQ91987.1 - 0.0034 17.4 0.0 0.0047 16.9 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Glyco_hydro_61 PF03443.14 EAQ91988.1 - 3.8e-32 111.9 0.0 4.5e-32 111.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Pectate_lyase_3 PF12708.7 EAQ91989.1 - 1.2e-30 107.0 5.4 2.7e-22 79.7 2.0 2.9 2 1 0 2 2 2 2 Pectate lyase superfamily protein NosD PF05048.13 EAQ91989.1 - 0.28 10.4 2.4 0.33 10.2 1.2 1.5 1 1 0 1 1 1 0 Periplasmic copper-binding protein (NosD) Fungal_trans PF04082.18 EAQ91993.1 - 0.011 14.8 0.0 0.021 13.9 0.0 1.4 1 0 0 1 1 1 0 Fungal specific transcription factor domain SnoaL_4 PF13577.6 EAQ91994.1 - 1.4e-17 64.0 0.4 1.9e-17 63.6 0.4 1.2 1 0 0 1 1 1 1 SnoaL-like domain RPE65 PF03055.15 EAQ91995.1 - 7e-100 335.4 0.0 8.1e-100 335.2 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein HET PF06985.11 EAQ91996.1 - 5e-17 62.6 0.1 1e-14 55.1 0.2 2.6 2 1 0 2 2 2 2 Heterokaryon incompatibility protein (HET) NPDC1 PF06809.11 EAQ91996.1 - 0.02 14.0 0.3 0.039 13.0 0.0 1.5 2 0 0 2 2 2 0 Neural proliferation differentiation control-1 protein (NPDC1) ArAE_2 PF10334.9 EAQ91996.1 - 0.086 12.7 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Aromatic acid exporter family member 2 p450 PF00067.22 EAQ91997.1 - 0.14 10.9 0.0 0.25 10.0 0.0 1.3 1 0 0 1 1 1 0 Cytochrome P450 Ank_2 PF12796.7 EAQ91998.1 - 3.9e-35 120.3 0.1 3.6e-09 37.1 0.0 5.4 3 1 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAQ91998.1 - 3e-28 94.7 0.1 5.3e-05 23.3 0.0 8.3 8 0 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.6 EAQ91998.1 - 7.3e-28 96.3 5.3 1.9e-09 37.6 0.1 7.1 4 3 3 7 7 7 7 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAQ91998.1 - 2.9e-26 91.5 0.2 7.8e-07 29.5 0.0 5.9 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 EAQ91998.1 - 3.6e-26 90.4 11.0 1.2e-05 25.5 0.1 7.7 7 0 0 7 7 7 5 Ankyrin repeat Cation_ATPase_C PF00689.21 EAQ91998.1 - 0.39 10.4 2.2 6.4 6.4 0.0 2.8 3 0 0 3 3 3 0 Cation transporting ATPase, C-terminus RT_RNaseH PF17917.1 EAQ92000.1 - 3.9e-32 110.7 0.0 9.1e-32 109.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 EAQ92000.1 - 1.1e-31 108.8 0.0 2.4e-31 107.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 EAQ92000.1 - 1.7e-24 86.6 0.0 3.5e-24 85.6 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 EAQ92000.1 - 2.4e-17 62.8 0.1 5.7e-17 61.6 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 EAQ92000.1 - 1.2e-13 51.3 0.0 3.8e-13 49.7 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 EAQ92000.1 - 5.8e-05 22.9 0.4 0.00016 21.5 0.4 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-CCHC PF00098.23 EAQ92000.1 - 0.00057 19.9 1.3 0.0012 18.8 1.3 1.6 1 0 0 1 1 1 1 Zinc knuckle MLVIN_C PF18697.1 EAQ92000.1 - 0.0028 17.7 0.0 0.0088 16.1 0.0 1.8 1 0 0 1 1 1 1 Murine leukemia virus (MLV) integrase (IN) C-terminal domain RVP_2 PF08284.11 EAQ92000.1 - 0.01 15.6 0.0 0.023 14.5 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 EAQ92000.1 - 0.013 15.8 0.3 0.19 12.0 0.1 2.8 2 0 0 2 2 2 0 Retrotransposon gag protein zf-CCHC_5 PF14787.6 EAQ92000.1 - 0.027 14.2 0.9 0.11 12.3 0.9 2.1 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-H2C2 PF09337.10 EAQ92000.1 - 0.062 13.5 0.0 0.25 11.6 0.0 2.0 2 0 0 2 2 2 0 H2C2 zinc finger Retrotran_gag_2 PF14223.6 EAQ92001.1 - 0.022 14.5 0.9 0.038 13.6 0.2 1.7 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type Spt46 PF17734.1 EAQ92001.1 - 0.045 13.6 0.8 0.07 12.9 0.8 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated protein 46 DNA_Packaging PF11053.8 EAQ92001.1 - 0.05 13.5 0.1 0.12 12.2 0.0 1.6 2 0 0 2 2 2 0 Terminase DNA packaging enzyme DUF3237 PF11578.8 EAQ92003.1 - 1.5e-27 96.3 0.0 1.6e-27 96.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) adh_short_C2 PF13561.6 EAQ92004.1 - 3.6e-34 118.4 0.4 4.1e-23 82.2 0.3 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EAQ92004.1 - 2e-28 99.2 0.3 2.6e-28 98.8 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EAQ92004.1 - 2.2e-07 31.0 0.2 3.1e-07 30.5 0.2 1.2 1 0 0 1 1 1 1 KR domain Ldh_1_N PF00056.23 EAQ92004.1 - 0.0058 16.7 0.1 0.014 15.5 0.1 1.6 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain p450 PF00067.22 EAQ92005.1 - 1.3e-62 212.1 0.0 1.6e-62 211.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF2834 PF11196.8 EAQ92006.1 - 0.54 10.6 6.3 2.1 8.7 1.5 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2834) FAD_binding_3 PF01494.19 EAQ92008.1 - 2.6e-25 89.4 0.0 4.2e-25 88.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 EAQ92008.1 - 2.2e-06 27.2 1.0 7.3e-05 22.2 0.2 2.3 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EAQ92008.1 - 0.00012 22.3 1.6 0.00024 21.3 0.6 2.2 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 EAQ92008.1 - 0.00017 21.0 1.1 0.036 13.4 0.0 2.8 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase DAO PF01266.24 EAQ92008.1 - 0.00053 19.7 2.6 0.0011 18.7 2.5 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EAQ92008.1 - 0.0015 17.8 1.0 0.073 12.3 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EAQ92008.1 - 0.0044 16.2 1.7 0.0044 16.2 1.7 1.6 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.21 EAQ92008.1 - 0.025 13.9 0.2 0.05 12.9 0.2 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 EAQ92008.1 - 0.029 13.6 0.1 0.055 12.7 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.27 EAQ92008.1 - 0.097 13.2 2.2 0.46 11.1 0.5 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.16 EAQ92009.1 - 2.3e-35 122.2 60.1 4e-25 88.5 20.3 3.2 1 1 2 3 3 3 3 Major Facilitator Superfamily Pyr_redox_3 PF13738.6 EAQ92010.1 - 6.3e-11 42.1 0.0 1.7e-08 34.1 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EAQ92010.1 - 9.3e-11 41.5 0.0 1.5e-09 37.5 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.19 EAQ92010.1 - 2.8e-08 32.7 0.0 0.00081 17.9 0.0 3.0 3 0 0 3 3 3 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 EAQ92010.1 - 0.00049 19.4 0.0 0.54 9.4 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EAQ92010.1 - 0.0046 17.0 0.1 1.1 9.2 0.0 2.8 2 1 0 2 2 2 2 FAD-NAD(P)-binding Amino_oxidase PF01593.24 EAQ92010.1 - 0.023 14.0 0.0 0.33 10.2 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase ketoacyl-synt PF00109.26 EAQ92011.1 - 4.9e-66 222.9 0.0 9e-66 222.0 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 EAQ92011.1 - 7.2e-59 198.7 0.2 3.7e-58 196.4 0.2 2.2 2 0 0 2 2 2 1 KR domain Ketoacyl-synt_C PF02801.22 EAQ92011.1 - 2.5e-30 104.9 0.1 1.3e-29 102.6 0.1 2.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.6 EAQ92011.1 - 9e-28 97.4 0.4 4.5e-13 49.1 0.0 3.6 2 1 1 3 3 3 3 Polyketide synthase dehydratase DUF4267 PF14087.6 EAQ92011.1 - 2.8e-26 91.8 2.3 2.8e-26 91.8 2.3 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4267) KAsynt_C_assoc PF16197.5 EAQ92011.1 - 2.8e-18 66.4 1.4 5.3e-17 62.3 0.0 3.7 5 0 0 5 5 4 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 EAQ92011.1 - 2.3e-09 37.0 1.3 8.2e-08 31.9 0.1 3.4 3 0 0 3 3 3 1 short chain dehydrogenase ADH_N PF08240.12 EAQ92011.1 - 5.8e-06 26.2 0.4 1.4e-05 24.9 0.4 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Acyl_transf_1 PF00698.21 EAQ92011.1 - 5.8e-05 22.7 4.7 0.00025 20.6 0.8 3.2 2 1 1 3 3 3 1 Acyl transferase domain ADH_zinc_N PF00107.26 EAQ92011.1 - 0.00017 21.6 0.1 0.00089 19.2 0.1 2.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Thiolase_N PF00108.23 EAQ92011.1 - 0.0018 17.7 0.1 0.0066 15.8 0.1 1.9 1 0 0 1 1 1 1 Thiolase, N-terminal domain PP-binding PF00550.25 EAQ92011.1 - 0.0019 18.5 0.1 0.013 15.8 0.0 2.5 2 0 0 2 2 2 1 Phosphopantetheine attachment site ADH_zinc_N_2 PF13602.6 EAQ92011.1 - 0.032 15.3 0.8 0.18 12.8 0.1 2.8 2 0 0 2 2 2 0 Zinc-binding dehydrogenase ACP_syn_III PF08545.10 EAQ92011.1 - 0.041 13.7 1.7 0.31 10.9 1.7 2.5 1 1 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GH131_N PF18271.1 EAQ92016.1 - 5e-75 252.5 0.1 5.8e-75 252.3 0.1 1.0 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain RVT_2 PF07727.14 EAQ92018.1 - 5.4e-34 117.9 0.0 1.2e-33 116.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 EAQ92018.1 - 5.8e-09 36.2 0.0 1.6e-08 34.7 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.6 EAQ92018.1 - 1.9e-06 27.6 0.0 3.5e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain DUF3237 PF11578.8 EAQ92020.1 - 4.1e-24 85.1 0.1 1e-23 83.9 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) Zn_clus PF00172.18 EAQ92020.1 - 4.4e-10 39.5 9.0 4.4e-10 39.5 9.0 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EAQ92020.1 - 0.0068 15.5 0.1 0.013 14.6 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3632 PF12311.8 EAQ92021.1 - 0.0059 17.1 0.0 0.067 13.6 0.0 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF3632) SKG6 PF08693.10 EAQ92022.1 - 0.01 15.2 0.1 0.01 15.2 0.1 1.7 2 0 0 2 2 2 0 Transmembrane alpha-helix domain DUF2681 PF10883.8 EAQ92022.1 - 0.088 13.2 0.1 0.15 12.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) MSA-2c PF12238.8 EAQ92022.1 - 0.3 11.1 5.3 0.39 10.7 5.3 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c SpoIIIAH PF12685.7 EAQ92022.1 - 0.62 9.9 2.6 1.3 8.8 0.0 2.0 2 0 0 2 2 2 0 SpoIIIAH-like protein CcmD PF04995.14 EAQ92022.1 - 2.1 8.5 5.3 0.41 10.8 1.1 1.9 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) Gly_transf_sug PF04488.15 EAQ92023.1 - 1.1e-06 29.2 0.0 4e-06 27.4 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif Beta-lactamase PF00144.24 EAQ92024.1 - 6.2e-26 91.4 1.3 9.6e-26 90.8 1.3 1.2 1 0 0 1 1 1 1 Beta-lactamase DUF2235 PF09994.9 EAQ92025.1 - 3.8e-20 72.4 2.1 2.8e-10 40.1 0.8 2.1 1 1 1 2 2 2 2 Uncharacterized alpha/beta hydrolase domain (DUF2235) p450 PF00067.22 EAQ92026.1 - 1.1e-56 192.6 0.0 1.3e-56 192.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF3176 PF11374.8 EAQ92028.1 - 1.5e-28 99.1 1.5 3.4e-28 97.9 1.5 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) LPMO_10 PF03067.15 EAQ92029.1 - 1.4e-06 29.1 0.0 2e-06 28.6 0.0 1.2 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading adh_short PF00106.25 EAQ92030.1 - 1.2e-40 139.1 0.0 1.7e-40 138.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EAQ92030.1 - 3.6e-26 92.2 0.4 4.6e-26 91.8 0.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EAQ92030.1 - 0.0047 16.8 0.5 0.013 15.4 0.5 1.6 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.10 EAQ92030.1 - 0.028 13.8 0.0 0.038 13.4 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 EAQ92030.1 - 0.073 12.5 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family MFS_1 PF07690.16 EAQ92031.1 - 2.7e-18 66.0 53.2 7.1e-10 38.3 28.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Hexapep PF00132.24 EAQ92031.1 - 4.4e-13 48.4 8.3 2.8e-11 42.7 4.8 3.7 4 0 0 4 4 4 1 Bacterial transferase hexapeptide (six repeats) Mac PF12464.8 EAQ92031.1 - 5.5e-13 48.9 0.0 9.3e-13 48.2 0.0 1.4 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep_2 PF14602.6 EAQ92031.1 - 5.1e-11 42.1 9.4 7e-10 38.5 4.3 3.6 4 0 0 4 4 4 2 Hexapeptide repeat of succinyl-transferase Pectate_lyase PF03211.13 EAQ92032.1 - 3.1e-82 275.1 4.1 9.5e-82 273.5 4.2 1.6 2 0 0 2 2 2 1 Pectate lyase UvrD_C_2 PF13538.6 EAQ92034.1 - 8.9e-05 22.2 0.0 0.00021 21.1 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.14 EAQ92034.1 - 0.0019 16.2 0.0 0.0026 15.8 0.0 1.1 1 0 0 1 1 1 1 Helicase PIF1 PF05970.14 EAQ92034.1 - 0.018 14.2 0.0 0.024 13.8 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase adh_short PF00106.25 EAQ92035.1 - 5.4e-10 39.0 0.0 1.7e-06 27.6 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 EAQ92035.1 - 4.2e-05 23.5 0.0 8.2e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.12 EAQ92035.1 - 0.0043 16.3 0.0 0.0065 15.7 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 EAQ92035.1 - 0.0078 15.7 0.0 0.031 13.7 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EAQ92035.1 - 0.039 13.8 0.0 0.2 11.6 0.0 2.1 3 0 0 3 3 3 0 NAD(P)H-binding Transp_cyt_pur PF02133.15 EAQ92035.1 - 0.092 11.5 0.1 0.16 10.7 0.1 1.3 1 0 0 1 1 1 0 Permease for cytosine/purines, uracil, thiamine, allantoin Fungal_trans PF04082.18 EAQ92036.1 - 0.004 16.2 0.0 0.0068 15.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2_11 PF16622.5 EAQ92036.1 - 0.052 13.3 1.9 0.14 11.9 1.9 1.7 1 0 0 1 1 1 0 zinc-finger C2H2-type zf-C2H2_4 PF13894.6 EAQ92036.1 - 0.93 10.5 4.9 0.31 12.0 0.8 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_6 PF13912.6 EAQ92036.1 - 1 9.4 5.8 0.17 11.9 0.8 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger Zn_ribbon_recom PF13408.6 EAQ92036.1 - 3.6 8.2 6.9 7.9 7.1 6.9 1.5 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain SET PF00856.28 EAQ92037.1 - 3.4e-11 43.8 0.0 7.9e-11 42.6 0.0 1.7 1 1 0 1 1 1 1 SET domain TPR_2 PF07719.17 EAQ92037.1 - 8.2e-06 25.6 10.6 0.0043 17.1 0.6 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 EAQ92037.1 - 0.0021 18.1 1.9 0.14 12.5 0.1 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 EAQ92037.1 - 0.051 13.4 10.9 0.59 10.1 1.4 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat BTAD PF03704.17 EAQ92037.1 - 0.071 13.5 6.4 0.8 10.1 3.0 2.6 1 1 1 2 2 2 0 Bacterial transcriptional activator domain TPR_14 PF13428.6 EAQ92037.1 - 0.16 12.8 0.4 0.16 12.8 0.4 3.4 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 EAQ92037.1 - 0.17 12.2 11.2 0.73 10.2 6.7 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat AA_permease_2 PF13520.6 EAQ92038.1 - 1.5e-33 116.3 33.6 4e-33 114.9 33.6 1.7 1 0 0 1 1 1 1 Amino acid permease Ank_2 PF12796.7 EAQ92038.1 - 1.4e-28 99.3 0.0 5.8e-11 42.8 0.3 4.9 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAQ92038.1 - 1.5e-26 92.1 0.6 9.2e-08 32.2 0.1 5.2 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 EAQ92038.1 - 2.7e-24 84.5 2.9 0.00013 22.3 0.0 7.8 7 0 0 7 7 7 5 Ankyrin repeat Ank_4 PF13637.6 EAQ92038.1 - 7.4e-21 74.2 2.5 3.4e-05 24.3 0.2 6.0 4 1 2 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAQ92038.1 - 1.6e-20 71.0 0.5 0.00067 19.9 0.0 6.7 6 0 0 6 6 6 4 Ankyrin repeat AA_permease PF00324.21 EAQ92038.1 - 7.1e-05 21.6 26.6 0.00012 20.8 26.6 1.3 1 0 0 1 1 1 1 Amino acid permease Hamartin PF04388.12 EAQ92040.1 - 8.2 5.0 14.1 9.4 4.8 14.1 1.1 1 0 0 1 1 1 0 Hamartin protein Sulfotransfer_4 PF17784.1 EAQ92041.1 - 1.9e-45 155.3 0.2 2.5e-45 154.9 0.2 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Crystall_3 PF08964.10 EAQ92042.1 - 0.08 13.1 0.0 0.084 13.1 0.0 1.1 1 0 0 1 1 1 0 Beta/Gamma crystallin MF_alpha_N PF05436.11 EAQ92042.1 - 0.22 11.5 1.3 3.6 7.6 0.0 2.1 1 1 1 2 2 2 0 Mating factor alpha precursor N-terminus DUF4044 PF13253.6 EAQ92042.1 - 4.6 6.8 5.9 5.4 6.6 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4044) Pyr_redox_2 PF07992.14 EAQ92044.1 - 1.1e-13 51.1 0.0 6.2e-10 38.8 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EAQ92044.1 - 0.002 17.7 0.3 0.0086 15.7 0.2 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EAQ92044.1 - 0.0038 17.2 0.0 0.12 12.4 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding Malic_M PF03949.15 EAQ92044.1 - 0.17 11.2 0.0 0.7 9.1 0.0 1.9 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain Piwi PF02171.17 EAQ92045.1 - 1.9e-58 198.1 0.0 1.7e-57 195.0 0.0 2.1 1 1 0 1 1 1 1 Piwi domain ArgoL1 PF08699.10 EAQ92045.1 - 2.5e-08 33.4 0.5 7e-08 32.0 0.2 1.9 2 0 0 2 2 2 1 Argonaute linker 1 domain ArgoN PF16486.5 EAQ92045.1 - 4.8e-07 30.5 0.1 4.4e-06 27.4 0.1 2.3 1 1 0 1 1 1 1 N-terminal domain of argonaute AAA_26 PF13500.6 EAQ92048.1 - 1e-10 41.8 0.0 2.2e-10 40.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain Aminotran_1_2 PF00155.21 EAQ92049.1 - 5.4e-23 81.7 0.0 2.2e-17 63.3 0.0 2.1 1 1 1 2 2 2 2 Aminotransferase class I and II OKR_DC_1 PF01276.20 EAQ92049.1 - 0.15 10.8 0.0 0.29 9.8 0.0 1.5 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Ada_Zn_binding PF02805.16 EAQ92051.1 - 1e-28 99.1 6.6 1.5e-28 98.6 5.6 1.8 2 0 0 2 2 2 1 Metal binding domain of Ada HTH_AraC PF00165.23 EAQ92051.1 - 5e-08 32.8 0.0 1.1e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_18 PF12833.7 EAQ92051.1 - 5.6e-06 26.5 0.7 1.6e-05 25.1 0.0 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain Epimerase PF01370.21 EAQ92052.1 - 3.9e-11 42.9 2.7 1.5e-09 37.6 0.7 3.2 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EAQ92052.1 - 1e-08 35.0 0.3 4.4e-07 29.6 0.1 2.2 1 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EAQ92052.1 - 5.8e-06 26.3 0.0 9.8e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 EAQ92052.1 - 5.4e-05 22.5 0.0 0.16 11.1 0.0 2.1 1 1 0 2 2 2 2 Male sterility protein KR PF08659.10 EAQ92052.1 - 0.0017 18.3 0.5 0.29 11.0 0.0 2.3 1 1 0 2 2 2 2 KR domain 3Beta_HSD PF01073.19 EAQ92052.1 - 0.0021 17.1 0.1 0.11 11.4 0.1 2.2 1 1 1 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 EAQ92052.1 - 0.012 15.1 0.1 0.028 13.9 0.0 1.8 2 0 0 2 2 2 0 short chain dehydrogenase Plant_zn_clust PF10533.9 EAQ92053.1 - 1.6 8.8 5.5 5 7.2 5.5 1.8 1 0 0 1 1 1 0 Plant zinc cluster domain Shadoo PF14999.6 EAQ92053.1 - 3.8 7.6 9.3 0.23 11.5 1.3 2.5 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective DUF1996 PF09362.10 EAQ92054.1 - 3.4e-76 256.3 3.4 4.2e-76 256.0 3.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) ADH_zinc_N PF00107.26 EAQ92055.1 - 3.2e-20 72.4 0.1 4.5e-20 72.0 0.1 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 EAQ92055.1 - 2.8e-18 65.8 0.0 6.4e-18 64.6 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 EAQ92055.1 - 8.6e-08 33.3 0.1 1.7e-07 32.4 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase CFEM PF05730.11 EAQ92056.1 - 2.9e-22 78.5 47.0 5.7e-11 42.4 9.6 4.5 4 1 1 5 5 5 3 CFEM domain zf-Sec23_Sec24 PF04810.15 EAQ92058.1 - 0.11 12.6 0.1 0.23 11.6 0.1 1.5 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger Glyco_tranf_2_4 PF13704.6 EAQ92059.1 - 0.14 12.7 0.1 0.47 11.0 0.0 1.9 2 0 0 2 2 2 0 Glycosyl transferase family 2 DUF3638 PF12340.8 EAQ92064.1 - 6e-87 290.7 0.0 1.3e-86 289.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.8 EAQ92064.1 - 8.7e-16 57.0 0.1 2.1e-15 55.8 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) CARD_2 PF16739.5 EAQ92064.1 - 0.095 12.7 0.1 0.29 11.1 0.1 1.8 1 0 0 1 1 1 0 Caspase recruitment domain RVT_2 PF07727.14 EAQ92065.1 - 2.6e-11 43.6 0.2 5.9e-06 26.1 0.0 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) gag_pre-integrs PF13976.6 EAQ92065.1 - 1.7e-06 27.8 0.0 5.7e-06 26.1 0.0 1.9 2 0 0 2 2 2 1 GAG-pre-integrase domain rve PF00665.26 EAQ92065.1 - 0.001 19.3 0.1 0.0024 18.0 0.1 1.6 1 0 0 1 1 1 1 Integrase core domain Cas_VVA1548 PF09652.10 EAQ92065.1 - 0.12 12.6 0.1 0.3 11.4 0.1 1.6 1 0 0 1 1 1 0 Putative CRISPR-associated protein (Cas_VVA1548) NAD_binding_10 PF13460.6 EAQ92066.1 - 0.027 14.4 0.0 0.14 12.0 0.0 1.9 2 0 0 2 2 2 0 NAD(P)H-binding Glyco_hydro_18 PF00704.28 EAQ92067.1 - 6.9e-54 183.7 0.3 8.4e-54 183.4 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 EAQ92067.1 - 0.00026 21.4 42.8 0.0036 17.8 15.6 2.9 3 0 0 3 3 3 2 Chitin recognition protein Caleosin PF05042.13 EAQ92068.1 - 6.8e-69 231.1 0.2 1.2e-67 227.1 0.2 2.0 1 1 0 1 1 1 1 Caleosin related protein EF-hand_6 PF13405.6 EAQ92068.1 - 6.7e-06 25.6 0.3 0.054 13.5 0.0 3.4 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.32 EAQ92068.1 - 0.00043 19.6 0.2 3.2 7.5 0.0 3.4 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.6 EAQ92068.1 - 0.0014 18.0 2.7 5.8 6.6 0.0 3.4 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 EAQ92068.1 - 0.039 14.4 0.0 5 7.7 0.0 2.9 3 0 0 3 3 3 0 EF-hand domain pair Glyco_hydro_10 PF00331.20 EAQ92069.1 - 2.4e-107 358.8 0.6 2.9e-107 358.5 0.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_1 PF00734.18 EAQ92069.1 - 9e-14 51.1 10.6 9e-14 51.1 10.6 2.5 3 0 0 3 3 3 1 Fungal cellulose binding domain Glyco_hydro_42 PF02449.15 EAQ92069.1 - 0.0038 16.6 0.2 0.025 13.9 0.0 1.9 1 1 1 2 2 2 1 Beta-galactosidase Ig_GlcNase PF18368.1 EAQ92070.1 - 9.9e-34 115.7 0.5 2.9e-33 114.2 0.0 2.1 2 0 0 2 2 2 1 Exo-beta-D-glucosaminidase Ig-fold domain Glyco_hydro_2 PF00703.21 EAQ92070.1 - 8.8e-12 45.7 1.4 2.9e-11 44.0 0.2 2.4 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Mannosidase_ig PF17786.1 EAQ92070.1 - 7.3e-08 32.9 0.5 7.3e-08 32.9 0.5 3.3 3 0 0 3 3 3 1 Mannosidase Ig/CBM-like domain Ig_mannosidase PF17753.1 EAQ92070.1 - 0.0004 20.1 0.4 0.0023 17.6 0.0 2.3 2 0 0 2 2 2 1 Ig-fold domain PIF1 PF05970.14 EAQ92071.1 - 4.6e-19 68.8 0.1 7.8e-19 68.1 0.1 1.3 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 EAQ92071.1 - 1.7e-07 31.1 0.0 7.2e-07 29.1 0.0 2.0 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.6 EAQ92071.1 - 0.001 19.4 0.0 0.0026 18.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 EAQ92071.1 - 0.027 14.3 0.0 0.075 12.9 0.0 1.8 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain RVT_1 PF00078.27 EAQ92072.1 - 2e-34 119.0 0.0 4e-34 118.1 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 EAQ92072.1 - 2.1e-25 88.9 0.9 4.8e-25 87.7 0.0 2.2 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 EAQ92072.1 - 0.0037 16.8 0.0 0.0084 15.6 0.0 1.7 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-RVT PF13966.6 EAQ92072.1 - 0.069 13.9 0.0 0.069 13.9 0.0 3.0 3 0 0 3 3 3 0 zinc-binding in reverse transcriptase DUF1043 PF06295.12 EAQ92072.1 - 0.62 10.1 6.9 2.3 8.2 6.9 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) Baculo_PEP_C PF04513.12 EAQ92072.1 - 1.1 9.4 4.2 3.6 7.6 4.2 1.9 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1640 PF07798.11 EAQ92072.1 - 2.5 8.1 15.0 7.1 6.7 15.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) Prominin PF05478.11 EAQ92072.1 - 2.5 5.9 7.8 5.1 4.9 7.8 1.4 1 0 0 1 1 1 0 Prominin UvrD_C_2 PF13538.6 EAQ92073.1 - 0.045 13.6 0.0 0.22 11.4 0.0 2.2 2 1 0 2 2 2 0 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.21 EAQ92075.1 - 1.2e-12 48.1 0.7 4.8e-08 32.9 0.0 2.6 1 1 0 2 2 2 2 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 EAQ92075.1 - 5.9e-12 46.1 0.0 1.6e-11 44.8 0.0 1.7 2 0 0 2 2 2 1 AAA domain UvrD_C_2 PF13538.6 EAQ92075.1 - 1.1e-09 38.0 0.0 2.5e-09 36.8 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 EAQ92075.1 - 0.00025 20.8 0.0 0.00071 19.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain UvrD_C PF13361.6 EAQ92075.1 - 0.00078 18.9 0.0 0.0013 18.1 0.0 1.4 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 EAQ92075.1 - 0.00093 19.0 0.1 1.3 8.7 0.0 3.5 3 1 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DEAD PF00270.29 EAQ92075.1 - 0.0064 16.3 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAQ92075.1 - 0.0081 16.4 0.0 0.025 14.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_12 PF13087.6 EAQ92075.1 - 0.01 15.4 0.0 0.043 13.4 0.0 2.1 2 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 EAQ92075.1 - 0.032 13.5 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_16 PF13191.6 EAQ92075.1 - 0.054 13.9 0.1 0.21 12.0 0.0 1.9 1 1 1 2 2 2 0 AAA ATPase domain MULE PF10551.9 EAQ92076.1 - 1.3e-18 67.2 0.0 2.7e-18 66.1 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain FAR1 PF03101.15 EAQ92076.1 - 0.0039 17.8 0.4 0.0093 16.6 0.4 1.6 1 0 0 1 1 1 1 FAR1 DNA-binding domain AT_hook PF02178.19 EAQ92076.1 - 0.2 11.6 8.8 0.44 10.6 4.3 3.1 2 0 0 2 2 2 0 AT hook motif ADP_ribosyl_GH PF03747.14 EAQ92077.1 - 2.3e-56 191.7 2.7 2.8e-56 191.4 2.7 1.1 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase CHAT PF12770.7 EAQ92078.1 - 2.6e-26 92.7 0.0 1.1e-25 90.6 0.0 2.1 1 1 0 1 1 1 1 CHAT domain DUF4805 PF16063.5 EAQ92079.1 - 0.016 14.6 0.3 0.023 14.1 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4805) Peptidase_C14 PF00656.22 EAQ92081.1 - 5.6e-11 42.9 0.0 8.3e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 Caspase domain zf-RVT PF13966.6 EAQ92081.1 - 0.071 13.8 0.0 0.17 12.6 0.0 1.6 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase Mac PF12464.8 EAQ92083.1 - 2.7e-11 43.5 0.0 4.6e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 Maltose acetyltransferase Peroxidase_2 PF01328.17 EAQ92084.1 - 6.9e-34 118.0 0.7 6e-18 66.0 0.1 2.1 1 1 1 2 2 2 2 Peroxidase, family 2 NAD_binding_8 PF13450.6 EAQ92087.1 - 6.8e-13 48.7 0.1 2e-12 47.1 0.1 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EAQ92087.1 - 5e-05 22.6 0.3 8.7e-05 21.8 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 EAQ92087.1 - 8.3e-05 22.3 0.7 0.00019 21.1 0.7 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EAQ92087.1 - 9e-05 21.3 0.1 0.00015 20.6 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein Lycopene_cycl PF05834.12 EAQ92087.1 - 0.00034 19.8 0.3 0.00048 19.3 0.3 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_oxidored PF12831.7 EAQ92087.1 - 0.00058 19.3 0.3 0.00094 18.6 0.3 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EAQ92087.1 - 0.00075 18.8 0.3 0.0014 17.9 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 EAQ92087.1 - 0.00085 18.6 0.1 0.0014 17.9 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Amino_oxidase PF01593.24 EAQ92087.1 - 0.00094 18.6 0.0 0.0018 17.6 0.0 1.4 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 EAQ92087.1 - 0.0011 18.2 0.4 0.0028 17.0 0.5 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EAQ92087.1 - 0.02 13.8 0.2 0.035 13.0 0.2 1.3 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox_3 PF13738.6 EAQ92087.1 - 0.039 13.2 0.1 0.065 12.5 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EAQ92087.1 - 0.08 13.5 0.2 0.2 12.2 0.2 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Ank_2 PF12796.7 EAQ92088.1 - 3.7e-25 88.3 0.1 2e-13 50.7 0.2 4.7 3 1 0 4 4 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAQ92088.1 - 2.5e-20 72.6 0.2 7.2e-07 29.6 0.0 5.9 6 0 0 6 6 5 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAQ92088.1 - 9.9e-16 57.6 7.4 0.00035 20.8 0.2 5.9 3 1 3 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAQ92088.1 - 1.4e-15 55.8 4.7 0.059 13.9 0.0 8.1 8 1 0 8 8 6 4 Ankyrin repeat Ank PF00023.30 EAQ92088.1 - 6.1e-13 48.6 6.6 0.076 13.5 0.1 6.5 7 0 0 7 7 5 4 Ankyrin repeat NACHT PF05729.12 EAQ92088.1 - 1.9e-06 27.9 0.0 3.4e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 EAQ92088.1 - 0.00011 22.5 0.0 0.00033 20.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain Patatin PF01734.22 EAQ92088.1 - 0.00015 22.0 0.0 0.00031 21.0 0.0 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase AAA_16 PF13191.6 EAQ92088.1 - 0.014 15.8 0.0 0.048 14.0 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain ATPase_2 PF01637.18 EAQ92088.1 - 0.015 15.2 0.0 0.038 13.9 0.0 1.7 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea KAP_NTPase PF07693.14 EAQ92088.1 - 0.019 14.2 0.0 0.034 13.4 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain ATP-synt_ab PF00006.25 EAQ92088.1 - 0.022 14.4 0.0 0.39 10.3 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain NB-ARC PF00931.22 EAQ92088.1 - 0.024 13.8 0.0 0.051 12.8 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Viral_helicase1 PF01443.18 EAQ92088.1 - 0.028 14.1 0.0 0.05 13.3 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.27 EAQ92088.1 - 0.04 14.4 0.0 0.11 13.1 0.0 1.6 1 0 0 1 1 1 0 ABC transporter RNA_helicase PF00910.22 EAQ92088.1 - 0.042 14.2 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.6 EAQ92088.1 - 0.077 13.0 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EAQ92088.1 - 0.082 12.7 0.1 0.22 11.3 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.6 EAQ92088.1 - 0.15 11.8 0.0 0.31 10.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain UvrD-helicase PF00580.21 EAQ92088.1 - 0.24 10.9 0.0 0.39 10.2 0.0 1.3 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain AltA1 PF16541.5 EAQ92089.1 - 7.7e-17 62.2 0.0 9.4e-17 61.9 0.0 1.1 1 0 0 1 1 1 1 Alternaria alternata allergen 1 LZ_Tnp_IS66 PF13007.7 EAQ92090.1 - 2 9.3 6.9 0.36 11.6 0.8 2.3 2 0 0 2 2 2 0 Transposase C of IS166 homeodomain ABC2_membrane_2 PF12679.7 EAQ92091.1 - 1.4 8.2 2.7 1.6 7.9 2.7 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein SID-1_RNA_chan PF13965.6 EAQ92091.1 - 1.6 7.0 7.9 2.2 6.6 7.9 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Membralin PF09746.9 EAQ92091.1 - 4.2 6.3 12.8 7.9 5.4 12.8 1.4 1 0 0 1 1 1 0 Tumour-associated protein Aminotran_3 PF00202.21 EAQ92094.1 - 5.1e-34 117.6 0.6 1.5e-30 106.2 0.1 2.1 2 0 0 2 2 2 2 Aminotransferase class-III SR-25 PF10500.9 EAQ92095.1 - 0.38 10.3 7.0 0.39 10.3 7.0 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein WD40 PF00400.32 EAQ92097.1 - 6.2e-08 33.2 8.7 0.15 13.0 0.0 4.5 4 0 0 4 4 4 4 WD domain, G-beta repeat VGCC_beta4Aa_N PF12052.8 EAQ92097.1 - 0.18 11.9 2.8 0.53 10.4 2.8 1.8 1 0 0 1 1 1 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal PH PF00169.29 EAQ92098.1 - 1e-13 51.7 0.1 2.4e-13 50.5 0.0 1.7 2 0 0 2 2 2 1 PH domain GRAM PF02893.20 EAQ92098.1 - 2e-08 34.1 0.0 0.0016 18.3 0.0 2.3 2 0 0 2 2 2 2 GRAM domain PH_11 PF15413.6 EAQ92098.1 - 1.2e-05 25.7 0.9 0.0004 20.8 0.9 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 EAQ92098.1 - 2.1e-05 24.7 0.0 3.8e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.6 EAQ92098.1 - 0.00031 20.8 0.0 0.00053 20.1 0.0 1.4 1 0 0 1 1 1 1 PH domain PH_6 PF15406.6 EAQ92098.1 - 0.0071 16.6 0.0 0.012 15.9 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain PH_2 PF08458.10 EAQ92098.1 - 0.09 13.1 0.0 0.15 12.4 0.0 1.3 1 0 0 1 1 1 0 Plant pleckstrin homology-like region PH_9 PF15410.6 EAQ92098.1 - 0.1 12.9 0.0 0.39 11.1 0.0 2.0 1 1 0 1 1 1 0 Pleckstrin homology domain GRAM PF02893.20 EAQ92099.1 - 1.7e-21 76.2 0.0 3e-21 75.4 0.0 1.4 1 0 0 1 1 1 1 GRAM domain Glyco_transf_28 PF03033.20 EAQ92099.1 - 2.1e-16 60.2 0.0 5.2e-16 58.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 EAQ92099.1 - 0.003 16.4 0.0 0.0067 15.3 0.0 1.4 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase NIF PF03031.18 EAQ92100.1 - 5.5e-27 94.5 0.3 2.5e-26 92.3 0.0 2.0 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase Biotin_lipoyl PF00364.22 EAQ92100.1 - 0.017 15.0 0.0 5.3 7.0 0.0 3.4 2 1 1 3 3 3 0 Biotin-requiring enzyme Peptidase_S64 PF08192.11 EAQ92100.1 - 0.096 11.2 0.3 0.15 10.5 0.3 1.2 1 0 0 1 1 1 0 Peptidase family S64 Cnd1_N PF12922.7 EAQ92101.1 - 2.6e-62 209.6 0.3 1.7e-61 206.9 0.1 2.4 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1, N-term Cnd1 PF12717.7 EAQ92101.1 - 8.7e-50 168.9 1.1 6.7e-45 153.0 0.1 3.3 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EAQ92101.1 - 1.3e-10 40.6 5.7 0.047 14.0 0.0 6.9 7 0 0 7 7 7 2 HEAT repeat HEAT_2 PF13646.6 EAQ92101.1 - 3e-09 37.1 3.6 0.00036 20.9 0.1 5.0 4 1 1 5 5 5 2 HEAT repeats HEAT_EZ PF13513.6 EAQ92101.1 - 3.1e-05 24.4 6.1 0.055 14.0 0.1 5.4 6 0 0 6 6 6 1 HEAT-like repeat RTP1_C1 PF10363.9 EAQ92101.1 - 0.0001 22.5 0.0 0.92 9.7 0.0 3.4 2 1 0 2 2 2 2 Required for nuclear transport of RNA pol II C-terminus 1 Cnd3 PF12719.7 EAQ92101.1 - 0.00019 20.7 8.9 0.0011 18.3 0.3 3.9 2 1 2 4 4 4 1 Nuclear condensing complex subunits, C-term domain Adaptin_N PF01602.20 EAQ92101.1 - 0.0018 16.9 2.4 0.03 12.9 0.1 3.2 3 1 0 3 3 3 1 Adaptin N terminal region DUF3597 PF12200.8 EAQ92101.1 - 0.15 12.6 0.7 5.9 7.4 0.0 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3597) Pkinase PF00069.25 EAQ92102.1 - 6.5e-42 143.7 0.0 3e-38 131.7 0.0 3.0 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ92102.1 - 3.9e-14 52.6 0.0 2.8e-08 33.4 0.0 3.5 4 0 0 4 4 4 2 Protein tyrosine kinase APH PF01636.23 EAQ92102.1 - 0.00031 20.7 0.2 0.037 14.0 0.1 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EAQ92102.1 - 0.0011 17.9 0.0 0.0023 16.8 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EAQ92102.1 - 0.0087 15.4 0.0 3.8 6.7 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Helicase_C_2 PF13307.6 EAQ92103.1 - 3.3e-56 190.1 0.0 8.4e-56 188.8 0.0 1.7 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.15 EAQ92103.1 - 9.8e-42 142.5 0.0 1.6e-41 141.9 0.0 1.3 1 0 0 1 1 1 1 DEAD_2 ResIII PF04851.15 EAQ92103.1 - 0.02 14.9 0.0 8.3 6.4 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit APG6_N PF17675.1 EAQ92104.1 - 0.014 15.9 5.2 0.024 15.2 5.2 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region VIR_N PF15912.5 EAQ92104.1 - 0.022 14.4 1.2 0.027 14.1 1.2 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal SCHIP-1 PF10148.9 EAQ92104.1 - 0.22 11.1 2.6 0.17 11.4 0.6 1.6 1 1 1 2 2 2 0 Schwannomin-interacting protein 1 DegS PF05384.11 EAQ92104.1 - 0.34 10.4 6.4 0.47 9.9 6.4 1.1 1 0 0 1 1 1 0 Sensor protein DegS Cep57_CLD_2 PF14197.6 EAQ92104.1 - 6.3 7.0 14.6 5.9 7.1 0.8 2.7 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 LptF_LptG PF03739.14 EAQ92106.1 - 3 6.6 8.6 0.11 11.3 1.8 1.8 2 0 0 2 2 2 0 Lipopolysaccharide export system permease LptF/LptG MOSC PF03473.17 EAQ92107.1 - 0.0032 17.5 0.1 0.0093 16.0 0.1 1.7 1 1 0 1 1 1 1 MOSC domain Esterase PF00756.20 EAQ92113.1 - 2.7e-06 27.2 0.0 4.3e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 EAQ92113.1 - 0.00098 18.6 0.1 0.0018 17.8 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Exonuc_VII_L PF02601.15 EAQ92113.1 - 0.025 14.2 4.5 0.033 13.8 4.5 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Pinin_SDK_N PF04697.13 EAQ92113.1 - 0.032 14.9 0.8 0.19 12.4 0.7 2.4 2 1 0 2 2 2 0 pinin/SDK conserved region Hydrolase_4 PF12146.8 EAQ92113.1 - 0.073 12.3 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 CorA PF01544.18 EAQ92113.1 - 1.2 8.4 4.8 1.8 7.8 4.8 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF1664 PF07889.12 EAQ92113.1 - 1.4 9.0 4.3 1.1 9.4 2.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Chitin_synth_2 PF03142.15 EAQ92114.1 - 0.0032 16.2 1.3 0.0032 16.2 1.3 2.2 2 1 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 EAQ92114.1 - 0.62 9.9 15.1 5.2 6.9 15.1 2.0 1 1 0 1 1 1 0 Glycosyl transferase family group 2 DUF5326 PF17260.2 EAQ92114.1 - 0.81 9.9 10.1 1 9.5 0.7 3.1 3 0 0 3 3 3 0 Family of unknown function (DUF5326) Glycophorin_A PF01102.18 EAQ92115.1 - 0.01 16.1 0.1 0.016 15.5 0.1 1.3 1 0 0 1 1 1 0 Glycophorin A Hol_Tox PF16935.5 EAQ92115.1 - 0.016 15.2 0.1 0.026 14.6 0.1 1.4 1 0 0 1 1 1 0 Putative Holin-like Toxin (Hol-Tox) Gram_pos_anchor PF00746.21 EAQ92115.1 - 0.048 13.6 1.2 0.099 12.6 1.2 1.5 1 0 0 1 1 1 0 LPXTG cell wall anchor motif Syndecan PF01034.20 EAQ92115.1 - 0.074 13.0 1.1 0.13 12.2 1.1 1.4 1 0 0 1 1 1 0 Syndecan domain SseC PF04888.12 EAQ92115.1 - 0.24 11.0 0.5 0.36 10.4 0.5 1.3 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family DUF4896 PF16237.5 EAQ92116.1 - 0.036 13.9 0.3 0.1 12.5 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4896) Ion_trans PF00520.31 EAQ92116.1 - 0.05 12.8 8.8 0.66 9.2 5.3 2.1 1 1 1 2 2 2 0 Ion transport protein DUF3433 PF11915.8 EAQ92116.1 - 0.1 13.1 2.4 1.4 9.5 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3433) COesterase PF00135.28 EAQ92117.1 - 8.4e-74 249.3 0.0 1.7e-69 235.1 0.0 2.0 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 EAQ92117.1 - 1.9e-05 24.6 0.0 3.7e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EAQ92117.1 - 0.053 12.8 0.0 0.085 12.1 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 p450 PF00067.22 EAQ92118.1 - 1.4e-40 139.5 0.0 4.4e-36 124.6 0.0 2.3 2 1 0 2 2 2 2 Cytochrome P450 MotA_ExbB PF01618.16 EAQ92118.1 - 0.48 10.2 2.5 1.5 8.6 0.0 2.5 2 0 0 2 2 2 0 MotA/TolQ/ExbB proton channel family Ank_4 PF13637.6 EAQ92121.1 - 1.3e-05 25.7 0.0 3.1e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAQ92121.1 - 0.0028 18.2 0.0 0.0051 17.4 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAQ92121.1 - 0.11 13.1 0.0 10 7.1 0.0 2.6 2 0 0 2 2 2 0 Ankyrin repeat Methyltransf_23 PF13489.6 EAQ92122.1 - 1.9e-06 27.8 0.2 0.03 14.2 0.0 2.4 1 1 1 2 2 2 2 Methyltransferase domain MULE PF10551.9 EAQ92123.1 - 3.2e-11 43.5 0.0 6.2e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 MULE transposase domain SWIM PF04434.17 EAQ92123.1 - 0.088 12.5 2.9 0.21 11.3 2.9 1.6 1 0 0 1 1 1 0 SWIM zinc finger Mito_carr PF00153.27 EAQ92124.1 - 7.6e-13 48.2 5.1 1.7e-08 34.2 0.1 3.4 3 1 0 3 3 3 2 Mitochondrial carrier protein Myf5 PF12232.8 EAQ92124.1 - 0.041 14.6 0.4 0.12 13.1 0.4 1.8 1 0 0 1 1 1 0 Myogenic determination factor 5 NPP1 PF05630.11 EAQ92126.1 - 8.7e-59 198.9 0.4 1e-58 198.7 0.4 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) Vps62 PF06101.11 EAQ92126.1 - 0.0094 14.3 0.7 0.013 13.9 0.7 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 62 Glyco_hydro_61 PF03443.14 EAQ92127.1 - 4.9e-42 144.2 0.5 1.3e-28 100.4 0.3 2.0 2 0 0 2 2 2 2 Glycosyl hydrolase family 61 AAA_16 PF13191.6 EAQ92128.1 - 4.3e-07 30.5 0.0 1.9e-06 28.4 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EAQ92128.1 - 7.6e-05 23.0 0.0 0.0004 20.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 EAQ92128.1 - 0.00088 19.2 0.0 0.002 18.1 0.0 1.6 1 0 0 1 1 1 1 NACHT domain RNA_helicase PF00910.22 EAQ92128.1 - 0.039 14.4 0.0 0.081 13.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Kinocilin PF15033.6 EAQ92128.1 - 0.041 13.5 0.0 0.1 12.2 0.0 1.6 1 0 0 1 1 1 0 Kinocilin protein ABC_tran PF00005.27 EAQ92128.1 - 0.18 12.3 0.0 0.43 11.1 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Rad17 PF03215.15 EAQ92128.1 - 0.19 11.6 0.0 0.34 10.8 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain Glyco_transf_90 PF05686.12 EAQ92129.1 - 4.7e-16 58.7 0.3 6.2e-10 38.5 0.0 3.3 3 0 0 3 3 3 3 Glycosyl transferase family 90 Arginase PF00491.21 EAQ92130.1 - 3.1e-40 138.4 0.1 3.6e-40 138.2 0.1 1.0 1 0 0 1 1 1 1 Arginase family MARVEL PF01284.23 EAQ92131.1 - 6e-07 29.6 11.8 9.3e-07 29.0 11.8 1.3 1 0 0 1 1 1 1 Membrane-associating domain DUF2070 PF09843.9 EAQ92131.1 - 0.83 7.9 5.9 0.86 7.8 5.9 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Wzy_C PF04932.15 EAQ92131.1 - 2.2 7.9 8.8 0.33 10.6 2.7 2.1 2 0 0 2 2 2 0 O-Antigen ligase Cnn_1N PF07989.11 EAQ92134.1 - 5.1e-22 77.8 7.8 5.1e-22 77.8 7.8 10.8 8 2 2 10 10 10 1 Centrosomin N-terminal motif 1 Mto2_bdg PF12808.7 EAQ92134.1 - 3.2e-08 33.7 9.2 3.2e-08 33.7 9.2 13.4 14 1 0 14 14 14 1 Micro-tubular organiser Mto1 C-term Mto2-binding region EzrA PF06160.12 EAQ92134.1 - 7.3e-05 21.1 26.1 7.3e-05 21.1 26.1 3.7 2 2 0 3 3 3 1 Septation ring formation regulator, EzrA Serglycin PF04360.12 EAQ92134.1 - 0.39 10.7 3.3 0.89 9.5 0.3 3.1 4 0 0 4 4 4 0 Serglycin ERM PF00769.19 EAQ92134.1 - 0.43 10.4 126.5 0.01 15.7 39.9 6.2 1 1 3 5 5 5 0 Ezrin/radixin/moesin family YabA PF06156.13 EAQ92134.1 - 3.8 8.2 83.4 0.87 10.3 1.7 10.8 3 2 7 10 10 10 0 Initiation control protein YabA Sec7 PF01369.20 EAQ92136.1 - 1.5e-27 96.4 0.0 3.4e-27 95.3 0.0 1.5 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.6 EAQ92136.1 - 2.2e-18 66.7 0.0 5.7e-18 65.4 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain adh_short PF00106.25 EAQ92137.1 - 4e-38 130.9 0.3 1.4e-37 129.1 0.3 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EAQ92137.1 - 1.7e-27 96.5 5.3 2.3e-14 53.5 1.4 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EAQ92137.1 - 3.7e-07 30.2 0.6 1.1e-06 28.7 0.7 1.6 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 EAQ92137.1 - 0.00046 19.7 0.2 0.00073 19.1 0.2 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Glyco_transf_4 PF13439.6 EAQ92137.1 - 3 7.8 5.3 0.85 9.6 0.1 2.5 2 1 0 2 2 2 0 Glycosyltransferase Family 4 UvrC_HhH_N PF08459.11 EAQ92138.1 - 0.17 11.8 0.0 0.33 10.9 0.0 1.4 1 0 0 1 1 1 0 UvrC Helix-hairpin-helix N-terminal Sel1 PF08238.12 EAQ92140.1 - 1.4e-20 73.3 25.3 3.8e-08 33.7 0.1 7.2 7 0 0 7 7 7 6 Sel1 repeat TPR_1 PF00515.28 EAQ92140.1 - 0.13 12.1 0.0 0.13 12.1 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat CSN8_PSD8_EIF3K PF10075.9 EAQ92141.1 - 1.5e-12 47.7 0.0 2.4e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family Coatomer_WDAD PF04053.14 EAQ92142.1 - 3e-146 488.0 0.0 4.1e-146 487.5 0.0 1.2 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.11 EAQ92142.1 - 1.5e-90 303.9 0.1 1.3e-89 300.8 0.1 2.0 1 1 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.32 EAQ92142.1 - 1.5e-36 123.8 16.4 1.6e-07 31.9 0.2 7.9 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAQ92142.1 - 2.8e-09 37.1 1.1 0.00017 21.8 0.0 5.6 3 2 4 7 7 7 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EAQ92142.1 - 0.08 11.6 6.7 6.5 5.3 0.0 3.8 3 1 1 4 4 4 0 Nucleoporin Nup120/160 Clathrin PF00637.20 EAQ92142.1 - 0.16 11.8 0.6 0.86 9.5 0.0 2.2 2 0 0 2 2 2 0 Region in Clathrin and VPS Glyco_transf_24 PF18404.1 EAQ92143.1 - 1.2e-117 392.1 0.4 1.9e-117 391.4 0.4 1.2 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_15 PF18403.1 EAQ92143.1 - 3.6e-55 187.2 1.1 7.4e-55 186.2 0.5 1.9 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_14 PF18402.1 EAQ92143.1 - 8.1e-49 166.9 0.2 8e-34 117.7 0.0 3.2 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_13 PF18401.1 EAQ92143.1 - 5.6e-48 162.3 0.0 9.3e-47 158.4 0.0 2.8 2 0 0 2 2 2 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 EAQ92143.1 - 3e-43 146.4 0.0 6e-43 145.4 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Thioredoxin_12 PF18400.1 EAQ92143.1 - 6e-40 137.1 0.1 1.7e-39 135.7 0.0 1.7 2 0 0 2 2 2 1 Thioredoxin-like domain Glyco_transf_8 PF01501.20 EAQ92143.1 - 0.00023 20.8 0.0 0.00047 19.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 8 SNF2_N PF00176.23 EAQ92144.1 - 4.4e-23 81.6 0.0 5.7e-23 81.2 0.0 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EAQ92144.1 - 7.8e-11 42.3 0.0 1.3e-10 41.5 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 EAQ92144.1 - 0.012 14.8 0.0 0.017 14.3 0.0 1.1 1 0 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 Rad54_N PF08658.10 EAQ92145.1 - 1.8e-58 197.7 1.6 2.3e-58 197.4 1.6 1.1 1 0 0 1 1 1 1 Rad54 N terminal Mito_carr PF00153.27 EAQ92146.1 - 8.6e-43 144.2 2.7 3e-18 65.5 0.1 3.9 4 1 0 4 4 4 3 Mitochondrial carrier protein NYN PF01936.18 EAQ92147.1 - 0.14 12.6 0.0 0.41 11.1 0.0 1.7 2 0 0 2 2 2 0 NYN domain GST_N PF02798.20 EAQ92148.1 - 1.3e-15 57.5 0.0 2.5e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EAQ92148.1 - 1.4e-15 57.5 0.0 3.5e-15 56.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EAQ92148.1 - 5.2e-12 45.8 0.0 8.9e-12 45.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EAQ92148.1 - 1.9e-11 44.1 0.0 1.3e-10 41.4 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EAQ92148.1 - 1e-10 41.7 0.0 1.7e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EAQ92148.1 - 1.2e-09 38.0 0.1 2.5e-09 37.0 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 EAQ92148.1 - 0.0035 17.9 0.0 0.1 13.2 0.0 2.2 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain Bromodomain PF00439.25 EAQ92149.1 - 2e-43 146.3 0.3 2.7e-20 72.2 0.2 2.5 2 0 0 2 2 2 2 Bromodomain BAH PF01426.18 EAQ92149.1 - 1.3e-15 57.4 0.3 1.3e-15 57.4 0.3 2.1 2 0 0 2 2 2 1 BAH domain CDC45 PF02724.14 EAQ92149.1 - 0.00034 19.1 4.0 0.00034 19.1 4.0 2.9 3 0 0 3 3 3 1 CDC45-like protein Nsp1_C PF05064.13 EAQ92149.1 - 0.043 13.6 0.7 0.1 12.4 0.7 1.6 1 0 0 1 1 1 0 Nsp1-like C-terminal region OTU PF02338.19 EAQ92151.1 - 5.5e-08 33.4 0.0 1e-07 32.5 0.0 1.5 1 0 0 1 1 1 1 OTU-like cysteine protease UN_NPL4 PF11543.8 EAQ92151.1 - 0.0027 18.1 0.0 0.0047 17.4 0.0 1.4 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 UBX PF00789.20 EAQ92151.1 - 0.0028 17.8 0.0 0.0052 17.0 0.0 1.4 1 0 0 1 1 1 1 UBX domain PB1 PF00564.24 EAQ92151.1 - 0.086 12.8 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 PB1 domain FmdA_AmdA PF03069.15 EAQ92152.1 - 9.9e-178 590.7 0.0 1.1e-177 590.5 0.0 1.0 1 0 0 1 1 1 1 Acetamidase/Formamidase family EI24 PF07264.11 EAQ92153.1 - 5.2e-12 46.4 9.1 5.6e-10 39.7 9.1 2.2 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) SKG6 PF08693.10 EAQ92153.1 - 0.055 12.9 0.1 0.16 11.4 0.1 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain EVC2_like PF12297.8 EAQ92153.1 - 0.089 11.5 0.0 0.12 11.0 0.0 1.2 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein Inp1 PF12634.7 EAQ92154.1 - 1.6e-34 118.8 0.0 3.3e-34 117.8 0.0 1.5 1 0 0 1 1 1 1 Inheritance of peroxisomes protein 1 CBS PF00571.28 EAQ92155.1 - 2.3e-14 53.5 1.1 0.00048 20.5 0.0 4.7 4 0 0 4 4 4 4 CBS domain BCOR PF15808.5 EAQ92155.1 - 2.1 8.5 10.0 0.057 13.6 2.3 2.2 3 0 0 3 3 3 0 BCL-6 co-repressor, non-ankyrin-repeat region Importin_rep_4 PF18808.1 EAQ92156.1 - 6.8e-32 109.6 7.3 5e-31 106.9 1.1 4.7 4 1 1 5 5 4 1 Importin repeat Importin_rep_5 PF18816.1 EAQ92156.1 - 4.3e-22 78.1 3.1 1.1e-21 76.8 0.8 2.8 2 0 0 2 2 2 1 Importin repeat HEAT_2 PF13646.6 EAQ92156.1 - 2.1e-19 69.7 16.1 1e-05 25.8 0.0 8.1 5 2 2 8 8 7 6 HEAT repeats HEAT_EZ PF13513.6 EAQ92156.1 - 5.2e-19 68.3 15.5 1.3e-10 41.6 0.1 8.8 8 1 2 10 10 8 2 HEAT-like repeat HEAT PF02985.22 EAQ92156.1 - 2.2e-17 61.6 16.8 0.0069 16.6 0.0 10.7 13 0 0 13 13 8 4 HEAT repeat Vac14_Fab1_bd PF12755.7 EAQ92156.1 - 7.4e-14 52.1 0.7 0.012 16.2 0.0 7.4 4 2 5 9 9 8 2 Vacuolar 14 Fab1-binding region Importin_rep_6 PF18829.1 EAQ92156.1 - 7.3e-13 48.6 1.2 9.3e-12 45.0 0.2 3.2 3 0 0 3 3 3 1 Importin repeat 6 DUF3385 PF11865.8 EAQ92156.1 - 1.6e-10 41.1 0.1 0.013 15.4 0.0 6.6 5 3 2 8 8 7 2 Domain of unknown function (DUF3385) RIX1 PF08167.12 EAQ92156.1 - 5.9e-09 35.9 0.0 0.014 15.2 0.0 4.9 3 1 2 5 5 5 1 rRNA processing/ribosome biogenesis Cnd1 PF12717.7 EAQ92156.1 - 1.4e-08 35.0 4.0 0.38 10.8 0.0 6.0 4 2 3 7 7 7 2 non-SMC mitotic condensation complex subunit 1 DRIM PF07539.12 EAQ92156.1 - 1.7e-08 33.3 5.5 0.0091 14.4 0.1 3.9 3 1 1 4 4 4 3 Down-regulated in metastasis MMS19_C PF12460.8 EAQ92156.1 - 5.1e-08 32.5 2.9 1.8e-05 24.0 0.1 4.2 3 1 0 3 3 3 1 RNAPII transcription regulator C-terminal IFRD PF05004.13 EAQ92156.1 - 1.2e-06 27.9 7.9 0.00054 19.2 0.1 5.2 4 2 1 5 5 5 2 Interferon-related developmental regulator (IFRD) CLASP_N PF12348.8 EAQ92156.1 - 5e-06 26.2 4.5 0.011 15.3 0.0 5.7 5 2 2 7 7 6 1 CLASP N terminal RTP1_C1 PF10363.9 EAQ92156.1 - 0.00029 21.0 0.9 0.4 10.9 0.2 4.8 4 1 1 5 5 4 1 Required for nuclear transport of RNA pol II C-terminus 1 UNC45-central PF11701.8 EAQ92156.1 - 0.00033 20.6 3.2 14 5.6 0.0 5.3 5 1 0 5 5 5 0 Myosin-binding striated muscle assembly central DUF4042 PF13251.6 EAQ92156.1 - 0.00033 20.4 0.3 7.1 6.3 0.0 4.7 5 0 0 5 5 4 0 Domain of unknown function (DUF4042) Vps35 PF03635.17 EAQ92156.1 - 0.00064 18.4 0.9 0.0026 16.3 0.8 1.9 2 0 0 2 2 2 1 Vacuolar protein sorting-associated protein 35 Xpo1 PF08389.12 EAQ92156.1 - 0.00081 19.5 3.0 0.0023 18.0 0.0 3.2 3 1 0 4 4 3 1 Exportin 1-like protein Dopey_N PF04118.14 EAQ92156.1 - 0.0013 17.9 1.8 0.12 11.4 0.0 3.2 2 1 1 3 3 3 1 Dopey, N-terminal Tti2 PF10521.9 EAQ92156.1 - 0.0052 16.4 0.0 0.94 9.0 0.0 3.5 2 1 0 2 2 2 1 Tti2 family Arm PF00514.23 EAQ92156.1 - 0.0056 16.7 14.0 0.38 10.9 0.0 5.8 7 0 0 7 7 6 2 Armadillo/beta-catenin-like repeat MMS19_N PF14500.6 EAQ92156.1 - 0.0091 15.6 2.1 6.6 6.2 0.2 4.2 5 0 0 5 5 5 0 Dos2-interacting transcription regulator of RNA-Pol-II V-ATPase_H_N PF03224.14 EAQ92156.1 - 0.027 13.8 5.9 1.2 8.4 0.1 3.8 2 2 0 2 2 2 0 V-ATPase subunit H DNA_alkylation PF08713.11 EAQ92156.1 - 0.055 13.2 0.4 0.33 10.6 0.0 2.6 3 0 0 3 3 2 0 DNA alkylation repair enzyme Cnd3 PF12719.7 EAQ92156.1 - 0.11 11.7 0.1 1.6 7.9 0.0 3.1 3 1 0 3 3 2 0 Nuclear condensing complex subunits, C-term domain TFCD_C PF12612.8 EAQ92156.1 - 0.23 11.2 3.7 1.1 9.0 0.0 3.8 4 2 2 6 6 6 0 Tubulin folding cofactor D C terminal Telomere_reg-2 PF10193.9 EAQ92156.1 - 0.26 11.7 3.0 1 9.9 0.2 3.5 3 0 0 3 3 3 0 Telomere length regulation protein IKBKB_SDD PF18397.1 EAQ92156.1 - 0.33 10.2 1.7 18 4.5 0.0 2.5 2 0 0 2 2 2 0 IQBAL scaffold dimerization domain AI-2E_transport PF01594.16 EAQ92156.1 - 0.41 9.7 1.3 0.8 8.8 0.5 1.9 2 0 0 2 2 2 0 AI-2E family transporter PAS_9 PF13426.7 EAQ92157.1 - 1.2e-26 92.9 0.0 7.4e-18 64.7 0.1 3.5 3 0 0 3 3 3 3 PAS domain PAS_3 PF08447.12 EAQ92157.1 - 6.2e-21 74.5 0.0 6.1e-12 45.7 0.0 3.5 3 0 0 3 3 3 3 PAS fold PAS PF00989.25 EAQ92157.1 - 1.8e-15 56.9 0.0 1.1e-05 25.4 0.0 3.9 3 1 0 3 3 3 3 PAS fold PAS_11 PF14598.6 EAQ92157.1 - 9.9e-08 32.1 0.0 0.00034 20.7 0.0 3.2 2 1 1 3 3 3 2 PAS domain PAS_4 PF08448.10 EAQ92157.1 - 1.8e-07 31.4 0.0 0.066 13.5 0.0 3.4 3 0 0 3 3 3 2 PAS fold PAS_2 PF08446.11 EAQ92157.1 - 0.00092 19.9 0.0 22 5.8 0.0 3.5 3 0 0 3 3 3 1 PAS fold TFIIA PF03153.13 EAQ92159.1 - 0.61 10.0 12.6 1.2 9.1 12.6 1.6 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RTA1 PF04479.13 EAQ92160.1 - 1.4e-32 113.0 6.8 1.1e-30 106.8 4.5 2.2 1 1 1 2 2 2 2 RTA1 like protein Gate PF07670.14 EAQ92160.1 - 0.064 13.5 0.5 0.064 13.5 0.5 2.0 2 0 0 2 2 2 0 Nucleoside recognition ATP1G1_PLM_MAT8 PF02038.16 EAQ92160.1 - 0.13 11.7 0.2 0.39 10.2 0.2 1.7 1 0 0 1 1 1 0 ATP1G1/PLM/MAT8 family DUF3995 PF13160.6 EAQ92160.1 - 0.17 12.2 0.2 0.17 12.2 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3995) Rsa3 PF14615.6 EAQ92161.1 - 2e-21 75.2 0.2 2.5e-21 75.0 0.2 1.1 1 0 0 1 1 1 1 Ribosome-assembly protein 3 W2 PF02020.18 EAQ92162.1 - 3.4e-18 65.6 8.9 8.7e-18 64.2 8.9 1.7 1 1 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon NTP_transferase PF00483.23 EAQ92162.1 - 1.4e-06 28.0 0.0 2.4e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase HSF_DNA-bind PF00447.17 EAQ92163.1 - 1.5e-27 96.0 0.4 3.2e-27 95.0 0.4 1.6 1 0 0 1 1 1 1 HSF-type DNA-binding Response_reg PF00072.24 EAQ92163.1 - 1.9e-23 82.7 0.1 5.6e-23 81.3 0.1 1.8 1 0 0 1 1 1 1 Response regulator receiver domain CENP-H PF05837.12 EAQ92163.1 - 0.0026 18.2 4.5 0.0026 18.2 4.5 2.1 2 0 0 2 2 2 1 Centromere protein H (CENP-H) CENP-Q PF13094.6 EAQ92163.1 - 0.0076 16.5 2.7 0.019 15.2 2.2 1.9 2 0 0 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit Lgl_C PF08596.10 EAQ92163.1 - 0.066 11.9 0.4 0.11 11.2 0.4 1.2 1 0 0 1 1 1 0 Lethal giant larvae(Lgl) like, C-terminal TMCO5 PF14992.6 EAQ92163.1 - 0.14 11.7 2.6 0.24 11.0 2.6 1.2 1 0 0 1 1 1 0 TMCO5 family Pneumo_M2 PF07380.11 EAQ92163.1 - 0.15 12.4 0.2 0.53 10.6 0.1 1.9 2 0 0 2 2 2 0 Pneumovirus M2 protein YabA PF06156.13 EAQ92163.1 - 0.17 12.5 1.7 0.46 11.1 1.7 1.7 1 0 0 1 1 1 0 Initiation control protein YabA I-set PF07679.16 EAQ92164.1 - 0.00071 19.6 0.2 14 5.8 0.0 4.9 5 0 0 5 5 5 2 Immunoglobulin I-set domain DUF1918 PF08940.11 EAQ92164.1 - 0.03 14.0 1.0 31 4.3 0.0 4.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1918) Peptidase_C12 PF01088.21 EAQ92165.1 - 6.9e-37 127.2 0.1 5.1e-25 88.5 0.1 2.2 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase, family 1 CDP-OH_P_transf PF01066.21 EAQ92166.1 - 3.2e-13 50.2 0.1 8.1e-13 49.0 0.1 1.7 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase tRNA-synt_2b PF00587.25 EAQ92167.1 - 6.4e-24 84.9 0.0 9.5e-22 77.8 0.0 2.6 2 1 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EAQ92167.1 - 2.5e-20 72.4 0.1 5.1e-20 71.4 0.1 1.6 1 0 0 1 1 1 1 Anticodon binding domain TGS PF02824.21 EAQ92167.1 - 5e-09 36.1 0.0 1e-08 35.1 0.0 1.6 1 0 0 1 1 1 1 TGS domain Transglut_core2 PF13369.6 EAQ92168.1 - 1.5e-17 63.6 0.0 2.7e-17 62.7 0.0 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily YccV-like PF08755.11 EAQ92168.1 - 5.4e-11 42.9 0.0 1.3e-10 41.6 0.0 1.7 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like F-box PF00646.33 EAQ92168.1 - 1.6e-08 34.2 1.3 3.6e-08 33.1 1.3 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EAQ92168.1 - 1.9e-06 27.7 2.3 3.9e-06 26.7 2.3 1.6 1 0 0 1 1 1 1 F-box-like Elongin_A PF06881.11 EAQ92168.1 - 0.029 14.9 0.1 0.073 13.6 0.1 1.7 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Ytp1 PF10355.9 EAQ92169.1 - 6.1e-119 396.3 6.7 9e-119 395.8 6.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 EAQ92169.1 - 2e-33 114.3 2.0 2e-33 114.3 2.0 3.6 4 0 0 4 4 4 1 Domain of unknown function (DUF2427) Peptidase_M15_4 PF13539.6 EAQ92169.1 - 0.31 11.6 2.4 1.2 9.7 0.7 2.5 2 0 0 2 2 2 0 D-alanyl-D-alanine carboxypeptidase DUF1700 PF08006.11 EAQ92169.1 - 5.2 6.6 9.9 0.67 9.5 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1700) Lactamase_B PF00753.27 EAQ92171.1 - 7.5e-19 68.5 6.1 4e-17 62.9 6.1 2.4 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily BLACT_WH PF17778.1 EAQ92171.1 - 1.7e-18 66.3 0.4 4.3e-18 65.0 0.0 1.9 2 0 0 2 2 2 1 Beta-lactamase associated winged helix domain Lactamase_B_2 PF12706.7 EAQ92171.1 - 4.3e-06 26.4 0.2 7.8e-06 25.5 0.2 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Smr PF01713.21 EAQ92171.1 - 0.11 12.9 0.3 5.4 7.5 0.2 2.4 2 0 0 2 2 2 0 Smr domain UCH PF00443.29 EAQ92172.1 - 7.7e-41 140.3 1.6 1.2e-40 139.6 1.6 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EAQ92172.1 - 7.9e-28 98.0 3.7 7.9e-28 98.0 3.7 1.5 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 EAQ92172.1 - 0.0063 16.8 0.2 0.0063 16.8 0.2 2.8 3 0 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein N6-adenineMlase PF10237.9 EAQ92173.1 - 1.4e-48 164.7 0.1 1.8e-48 164.4 0.1 1.1 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase Epimerase PF01370.21 EAQ92174.1 - 9e-16 58.1 0.1 5e-15 55.6 0.0 2.1 2 1 1 3 3 3 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 EAQ92174.1 - 1.1e-15 57.9 0.1 2.5e-15 56.7 0.1 1.4 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EAQ92174.1 - 1.1e-14 54.7 0.0 2.2e-14 53.8 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 EAQ92174.1 - 5.5e-10 38.7 0.1 1.3e-09 37.5 0.1 1.6 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EAQ92174.1 - 9.9e-09 35.0 0.3 1.9e-08 34.1 0.1 1.5 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 EAQ92174.1 - 7.9e-07 28.5 0.0 3.1e-05 23.2 0.0 2.7 1 1 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 EAQ92174.1 - 2.3e-05 24.0 0.0 4.1e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EAQ92174.1 - 0.0031 17.5 0.0 0.4 10.6 0.0 2.6 3 0 0 3 3 3 1 KR domain NAD_binding_4 PF07993.12 EAQ92174.1 - 0.0042 16.3 0.7 0.34 10.0 0.2 2.7 2 1 0 2 2 2 1 Male sterility protein adh_short_C2 PF13561.6 EAQ92174.1 - 0.0045 16.6 0.0 0.0072 15.9 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.15 EAQ92174.1 - 0.014 14.6 0.0 0.029 13.5 0.0 1.5 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein 2-Hacid_dh_C PF02826.19 EAQ92174.1 - 0.038 13.4 0.2 0.86 8.9 0.1 2.4 1 1 1 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 EAQ92174.1 - 0.055 13.6 0.0 0.2 11.8 0.0 1.9 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase PCI PF01399.27 EAQ92175.1 - 1.9e-10 41.2 0.0 5e-10 39.8 0.0 1.8 1 0 0 1 1 1 1 PCI domain Rpn9_C PF18261.1 EAQ92175.1 - 4.3e-07 29.4 1.2 8.5e-07 28.5 1.2 1.5 1 0 0 1 1 1 1 Rpn9 C-terminal helix Dam PF05869.11 EAQ92175.1 - 0.0097 15.5 0.0 0.061 12.9 0.0 2.1 2 1 0 2 2 2 1 DNA N-6-adenine-methyltransferase (Dam) Gaa1 PF04114.14 EAQ92176.1 - 3.8e-134 448.4 0.0 5.1e-134 448.0 0.0 1.1 1 0 0 1 1 1 1 Gaa1-like, GPI transamidase component Rhomboid PF01694.22 EAQ92177.1 - 4.6e-05 23.5 0.7 4.6e-05 23.5 0.7 1.7 2 1 0 2 2 2 1 Rhomboid family Promethin PF16015.5 EAQ92177.1 - 0.47 10.4 5.4 0.45 10.4 3.2 1.9 2 0 0 2 2 2 0 Promethin Aconitase PF00330.20 EAQ92178.1 - 1.1e-147 492.8 0.0 1.3e-147 492.5 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EAQ92178.1 - 2.9e-43 147.3 0.0 5e-43 146.6 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain zf-C2H2_jaz PF12171.8 EAQ92179.1 - 8.4e-10 38.7 0.2 1.2e-09 38.2 0.2 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-U1 PF06220.12 EAQ92179.1 - 0.024 14.4 0.0 0.054 13.3 0.0 1.6 1 0 0 1 1 1 0 U1 zinc finger zf-SCNM1 PF15803.5 EAQ92179.1 - 0.059 13.0 0.2 0.1 12.3 0.2 1.3 1 0 0 1 1 1 0 Zinc-finger of sodium channel modifier 1 HAD_SAK_1 PF10307.9 EAQ92180.1 - 1.3e-74 250.5 0.0 1.8e-74 249.9 0.0 1.2 1 0 0 1 1 1 1 HAD domain family 1 in Swiss Army Knife RNA repair proteins SUIM_assoc PF16619.5 EAQ92180.1 - 0.15 12.2 16.9 0.69 10.0 6.0 2.5 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 EAQ92180.1 - 3.1 7.3 14.3 0.23 11.0 3.7 2.6 3 0 0 3 3 3 0 Spt20 family Metallopep PF12044.8 EAQ92181.1 - 1.1e-168 561.3 0.0 1.4e-168 561.0 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Peptidase_M10 PF00413.24 EAQ92181.1 - 0.037 13.9 0.1 0.07 13.0 0.1 1.4 1 0 0 1 1 1 0 Matrixin Jacalin PF01419.17 EAQ92181.1 - 0.081 12.9 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Jacalin-like lectin domain Peptidase_M66 PF10462.9 EAQ92181.1 - 0.15 11.0 0.5 0.24 10.3 0.5 1.2 1 0 0 1 1 1 0 Peptidase M66 Whi5 PF08528.11 EAQ92183.1 - 2.2e-07 30.4 0.4 4.7e-07 29.3 0.4 1.6 1 0 0 1 1 1 1 Whi5 like SKG6 PF08693.10 EAQ92184.1 - 0.00034 20.0 1.7 0.00034 20.0 1.7 2.6 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Peptidase_C14 PF00656.22 EAQ92186.1 - 1.1e-64 218.7 0.0 1.5e-64 218.4 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.6 EAQ92186.1 - 0.071 13.1 0.0 0.46 10.4 0.0 2.2 3 0 0 3 3 3 0 Raptor N-terminal CASPase like domain PACT_coil_coil PF10495.9 EAQ92187.1 - 1.6e-28 99.1 0.9 1.6e-28 99.1 0.9 5.1 6 0 0 6 6 6 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein Cnn_1N PF07989.11 EAQ92187.1 - 7.1e-27 93.4 4.7 7.1e-27 93.4 4.7 16.8 6 5 9 16 16 16 2 Centrosomin N-terminal motif 1 TPR_MLP1_2 PF07926.12 EAQ92187.1 - 1.3e-05 25.3 45.2 0.00012 22.1 18.0 13.2 3 1 9 12 12 12 4 TPR/MLP1/MLP2-like protein Seryl_tRNA_N PF02403.22 EAQ92187.1 - 0.00023 21.4 8.2 0.00023 21.4 8.2 14.1 4 2 9 14 14 14 1 Seryl-tRNA synthetase N-terminal domain Spc7 PF08317.11 EAQ92187.1 - 0.00034 19.6 27.0 0.00034 19.6 27.0 9.5 2 1 6 9 9 9 5 Spc7 kinetochore protein GAS PF13851.6 EAQ92187.1 - 0.0033 16.8 33.5 0.0033 16.8 33.5 11.0 3 3 9 12 12 12 3 Growth-arrest specific micro-tubule binding APG6_N PF17675.1 EAQ92187.1 - 0.011 16.3 18.2 0.011 16.3 18.2 13.2 1 1 10 11 11 11 0 Apg6 coiled-coil region Fez1 PF06818.15 EAQ92187.1 - 0.04 14.4 190.4 0.12 12.8 20.1 9.1 1 1 8 9 9 9 0 Fez1 DUF4611 PF15387.6 EAQ92188.1 - 0.061 13.5 7.6 0.97 9.7 0.3 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) DivIC PF04977.15 EAQ92188.1 - 0.58 10.0 3.4 22 4.9 0.0 2.9 3 0 0 3 3 3 0 Septum formation initiator Vac14_Fig4_bd PF11916.8 EAQ92189.1 - 1.6e-48 164.7 12.7 1.1e-24 87.1 1.4 2.7 2 1 1 3 3 3 2 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 EAQ92189.1 - 6e-44 148.6 0.1 3e-41 140.0 0.1 3.4 3 0 0 3 3 3 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 EAQ92189.1 - 4.2e-07 30.1 0.8 0.0011 19.1 0.4 3.1 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EAQ92189.1 - 6.6e-07 29.1 0.3 0.00058 19.9 0.0 4.5 4 0 0 4 4 4 1 HEAT repeat HEAT_EZ PF13513.6 EAQ92189.1 - 4.1e-06 27.2 5.4 0.0047 17.4 0.3 5.1 4 0 0 4 4 4 1 HEAT-like repeat Arm PF00514.23 EAQ92189.1 - 0.0014 18.6 0.0 0.22 11.6 0.0 3.7 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 EAQ92189.1 - 0.0036 17.6 2.7 0.38 11.2 0.1 4.1 5 0 0 5 5 5 1 HEAT repeats Tti2 PF10521.9 EAQ92189.1 - 0.053 13.0 0.1 0.47 10.0 0.0 2.6 3 0 0 3 3 3 0 Tti2 family FA_desaturase PF00487.24 EAQ92191.1 - 9.5e-16 58.4 0.7 1.5e-15 57.7 0.7 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 EAQ92191.1 - 1.2e-09 38.1 0.0 2.1e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Pyr_redox_2 PF07992.14 EAQ92192.1 - 1.7e-69 234.3 6.9 2.6e-69 233.7 6.5 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EAQ92192.1 - 1.9e-39 134.3 0.0 6.6e-39 132.6 0.0 2.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 EAQ92192.1 - 3.1e-25 88.5 10.6 7.7e-22 77.7 1.5 3.4 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EAQ92192.1 - 6.8e-12 45.4 2.9 1.9e-06 28.0 0.5 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 EAQ92192.1 - 2.3e-09 37.1 7.5 7.1e-09 35.5 0.4 2.9 2 1 1 3 3 3 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 EAQ92192.1 - 3.8e-09 36.2 0.8 0.0024 17.2 0.0 2.5 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 EAQ92192.1 - 2.3e-08 33.5 10.5 7.4e-07 28.6 3.3 3.1 2 2 1 3 3 3 2 Glucose inhibited division protein A DAO PF01266.24 EAQ92192.1 - 2.4e-08 34.0 11.1 0.0017 18.0 0.3 4.1 4 0 0 4 4 4 3 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EAQ92192.1 - 7.8e-08 31.9 6.3 6.9e-06 25.5 0.1 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EAQ92192.1 - 2.4e-07 30.2 8.3 1.2e-06 27.9 2.3 3.3 3 1 0 3 3 3 1 FAD binding domain HI0933_like PF03486.14 EAQ92192.1 - 2.9e-07 29.6 12.8 0.00011 21.1 1.8 4.0 4 0 0 4 4 4 3 HI0933-like protein FAD_binding_3 PF01494.19 EAQ92192.1 - 3.9e-06 26.4 7.8 0.11 11.8 0.0 3.3 3 0 0 3 3 3 3 FAD binding domain Thi4 PF01946.17 EAQ92192.1 - 0.00019 20.8 1.7 0.00055 19.2 0.1 2.1 2 0 0 2 2 2 1 Thi4 family K_oxygenase PF13434.6 EAQ92192.1 - 0.0003 20.0 1.6 0.1 11.7 0.1 2.5 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.6 EAQ92192.1 - 0.0026 18.2 3.1 1.7 9.2 0.1 3.0 2 1 0 2 2 2 2 Putative NAD(P)-binding Lycopene_cycl PF05834.12 EAQ92192.1 - 0.014 14.5 3.9 0.12 11.5 0.7 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein 3HCDH_N PF02737.18 EAQ92192.1 - 0.023 14.6 0.6 0.023 14.6 0.6 2.4 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Trp_halogenase PF04820.14 EAQ92192.1 - 0.032 13.1 5.0 0.061 12.2 0.7 2.4 2 0 0 2 2 2 0 Tryptophan halogenase 2-Hacid_dh_C PF02826.19 EAQ92192.1 - 0.046 13.1 0.8 5.1 6.4 0.1 2.4 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 EAQ92192.1 - 0.052 13.1 3.2 0.61 9.6 0.1 2.5 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FMO-like PF00743.19 EAQ92192.1 - 0.23 9.8 2.1 0.97 7.8 0.4 2.1 2 0 0 2 2 2 0 Flavin-binding monooxygenase-like MIF4G PF02854.19 EAQ92193.1 - 1.6e-22 80.2 0.3 2.6e-19 69.7 0.0 2.3 2 0 0 2 2 2 2 MIF4G domain MA3 PF02847.17 EAQ92193.1 - 5e-17 61.9 0.1 5.8e-16 58.5 0.0 2.9 4 1 0 4 4 4 1 MA3 domain SRP14 PF02290.15 EAQ92194.1 - 7.9e-26 90.3 0.0 1.2e-25 89.6 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle 14kD protein RRM_1 PF00076.22 EAQ92195.1 - 5.4e-54 179.9 0.0 1.1e-17 63.6 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 EAQ92195.1 - 4.3e-06 26.7 0.1 2.5 8.3 0.0 4.3 3 2 0 3 3 3 2 Limkain b1 RRM_3 PF08777.11 EAQ92195.1 - 1.1e-05 25.4 0.0 0.47 10.5 0.0 3.3 3 0 0 3 3 3 2 RNA binding motif ATP-grasp_2 PF08442.10 EAQ92195.1 - 0.0023 17.6 0.0 0.11 12.1 0.0 2.7 3 0 0 3 3 3 1 ATP-grasp domain RRM_occluded PF16842.5 EAQ92195.1 - 0.0099 15.7 0.0 7.8 6.4 0.0 3.1 3 0 0 3 3 3 1 Occluded RNA-recognition motif RRM_5 PF13893.6 EAQ92195.1 - 0.013 15.1 0.0 4.6 6.8 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PknH_C PF14032.6 EAQ92195.1 - 0.06 13.2 0.9 28 4.5 0.0 3.4 4 0 0 4 4 4 0 PknH-like extracellular domain DUF2457 PF10446.9 EAQ92195.1 - 1 8.5 7.8 1.4 8.0 7.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) THRAP3_BCLAF1 PF15440.6 EAQ92195.1 - 2.9 6.8 19.2 4.2 6.3 19.2 1.2 1 0 0 1 1 1 0 THRAP3/BCLAF1 family COQ9 PF08511.11 EAQ92196.1 - 7.2e-28 96.2 0.0 1.3e-27 95.4 0.0 1.4 1 0 0 1 1 1 1 COQ9 SMC_N PF02463.19 EAQ92197.1 - 3.3e-26 92.1 0.0 8e-26 90.8 0.0 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EAQ92197.1 - 4.9e-15 56.6 13.2 4.9e-15 56.6 13.2 4.4 2 2 0 2 2 2 1 AAA domain AAA_15 PF13175.6 EAQ92197.1 - 3.2e-09 37.0 2.5 3.2e-09 37.0 2.5 3.2 2 1 1 3 3 3 1 AAA ATPase domain AAA_21 PF13304.6 EAQ92197.1 - 0.00013 21.9 6.2 0.0024 17.8 0.5 3.4 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system Sec34 PF04136.15 EAQ92197.1 - 0.00051 19.9 3.5 0.00051 19.9 3.5 3.0 4 0 0 4 4 4 1 Sec34-like family AAA_29 PF13555.6 EAQ92197.1 - 0.0014 18.4 0.0 0.003 17.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.6 EAQ92197.1 - 0.0041 17.3 0.0 0.014 15.6 0.0 1.9 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit ABC_tran PF00005.27 EAQ92197.1 - 0.18 12.3 19.2 15 6.1 8.1 4.9 2 2 0 2 2 2 0 ABC transporter Spc7 PF08317.11 EAQ92197.1 - 4.4 6.1 49.5 0.42 9.4 14.8 3.5 2 1 1 3 3 3 0 Spc7 kinetochore protein SGT1 PF07093.11 EAQ92198.1 - 2.3e-80 270.7 0.0 6e-69 233.0 0.0 3.9 4 0 0 4 4 4 4 SGT1 protein DUF3439 PF11921.8 EAQ92198.1 - 0.14 12.2 1.3 0.23 11.5 1.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) THUMP PF02926.17 EAQ92201.1 - 3.8e-09 36.8 0.1 2.5e-06 27.7 0.1 2.3 2 0 0 2 2 2 2 THUMP domain POC3_POC4 PF10448.9 EAQ92201.1 - 0.16 12.0 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 20S proteasome chaperone assembly proteins 3 and 4 TPP_enzyme_N PF02776.18 EAQ92202.1 - 8.7e-33 113.3 0.0 3e-32 111.6 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 EAQ92202.1 - 7.7e-25 87.2 0.0 1.8e-24 86.1 0.0 1.6 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 EAQ92202.1 - 1.5e-15 57.3 0.6 6.7e-15 55.2 0.0 2.4 2 1 1 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.6 EAQ92202.1 - 0.12 11.5 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.20 EAQ92202.1 - 0.12 11.3 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 Dehydrogenase E1 component HEM4 PF02602.15 EAQ92203.1 - 1.8e-42 145.3 0.0 2.3e-42 144.9 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD TLD PF07534.16 EAQ92204.1 - 2e-25 89.7 0.0 1.5e-14 54.4 0.0 2.2 2 0 0 2 2 2 2 TLD Pkinase PF00069.25 EAQ92205.1 - 2.2e-68 230.5 0.0 2.7e-68 230.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ92205.1 - 4.6e-32 111.3 0.0 6e-32 110.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EAQ92205.1 - 0.00032 20.1 0.3 0.00053 19.4 0.3 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EAQ92205.1 - 0.00075 18.5 0.2 0.0012 17.9 0.2 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EAQ92205.1 - 0.0058 16.0 0.0 0.0098 15.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EAQ92205.1 - 0.026 14.5 0.2 0.054 13.4 0.2 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EAQ92205.1 - 0.048 12.7 0.0 0.073 12.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Gag_p6 PF08705.11 EAQ92205.1 - 0.1 12.8 0.1 0.21 11.9 0.1 1.4 1 0 0 1 1 1 0 Gag protein p6 S_100 PF01023.19 EAQ92205.1 - 0.13 12.0 0.3 0.39 10.5 0.3 1.8 1 0 0 1 1 1 0 S-100/ICaBP type calcium binding domain Sec23_trunk PF04811.15 EAQ92206.1 - 5.7e-71 238.9 0.0 1.3e-70 237.8 0.0 1.6 2 0 0 2 2 2 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 EAQ92206.1 - 1.9e-22 79.0 0.0 7.9e-22 77.0 0.0 2.1 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 EAQ92206.1 - 5.2e-18 65.6 0.1 1.1e-17 64.6 0.1 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 EAQ92206.1 - 1.5e-16 60.2 4.7 2.6e-16 59.4 4.7 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 EAQ92206.1 - 1.8e-10 40.5 0.0 4.4e-10 39.3 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 EAQ92206.1 - 0.036 13.4 0.1 0.076 12.4 0.1 1.4 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain EptA_B_N PF08019.12 EAQ92207.1 - 0.032 14.1 0.0 0.042 13.7 0.0 1.1 1 0 0 1 1 1 0 Phosphoethanolamine transferase EptA/EptB SARAF PF06682.12 EAQ92207.1 - 0.046 13.4 0.0 0.047 13.3 0.0 1.2 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Fijivirus_P9-2 PF06837.11 EAQ92207.1 - 0.12 11.8 0.0 0.14 11.6 0.0 1.1 1 0 0 1 1 1 0 Fijivirus P9-2 protein DC_STAMP PF07782.13 EAQ92207.1 - 0.16 11.8 0.0 0.19 11.5 0.0 1.1 1 0 0 1 1 1 0 DC-STAMP-like protein Fungal_trans_2 PF11951.8 EAQ92208.1 - 1.4e-07 30.7 0.0 3.1e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain SR-25 PF10500.9 EAQ92208.1 - 0.99 9.0 11.2 1.6 8.3 11.2 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein PAP1 PF08601.10 EAQ92208.1 - 3.5 7.2 9.0 6.9 6.3 9.0 1.4 1 0 0 1 1 1 0 Transcription factor PAP1 Xpo1 PF08389.12 EAQ92209.1 - 6.2e-07 29.6 0.0 3.3e-05 24.0 0.0 2.9 2 0 0 2 2 2 1 Exportin 1-like protein IBN_N PF03810.19 EAQ92209.1 - 8.6e-05 22.4 0.0 0.0049 16.8 0.0 3.5 2 0 0 2 2 2 1 Importin-beta N-terminal domain WD40 PF00400.32 EAQ92210.1 - 0.21 12.5 0.6 16 6.6 0.0 3.8 5 0 0 5 5 5 0 WD domain, G-beta repeat DUF1917 PF08939.10 EAQ92211.1 - 6.7e-85 285.2 0.0 8.5e-85 284.8 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1917) Syntaxin-6_N PF09177.11 EAQ92211.1 - 0.15 12.6 0.1 0.34 11.5 0.0 1.6 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Acetyltransf_1 PF00583.25 EAQ92212.1 - 1.2e-16 61.0 0.0 1.5e-16 60.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EAQ92212.1 - 1.2e-08 35.2 0.0 1.7e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EAQ92212.1 - 1.7e-08 34.4 0.0 2.4e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EAQ92212.1 - 5.6e-08 32.6 0.0 8e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 EAQ92212.1 - 9.8e-06 26.3 0.0 1.2e-05 26.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EAQ92212.1 - 1.2e-05 25.4 0.0 2e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 EAQ92212.1 - 0.00011 22.0 0.0 0.00014 21.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EAQ92212.1 - 0.0075 16.4 0.0 0.01 16.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EAQ92212.1 - 0.028 14.5 0.0 0.052 13.7 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase LCAT PF02450.15 EAQ92213.1 - 9.9e-84 281.8 0.1 9.2e-55 186.4 0.0 2.0 1 1 1 2 2 2 2 Lecithin:cholesterol acyltransferase DUF2013 PF09431.10 EAQ92214.1 - 3.3e-51 173.1 1.2 6.5e-51 172.1 1.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2013) Pathogen_betaC1 PF09593.10 EAQ92214.1 - 0.18 11.8 0.0 0.33 10.9 0.0 1.3 1 0 0 1 1 1 0 Beta-satellite pathogenicity beta C1 protein Ribosomal_S17 PF00366.20 EAQ92215.1 - 3.6e-22 78.3 1.2 4.5e-22 77.9 0.4 1.6 2 0 0 2 2 2 1 Ribosomal protein S17 AAA PF00004.29 EAQ92216.1 - 5.1e-38 130.5 0.0 1.1e-37 129.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 EAQ92216.1 - 3.4e-09 36.5 0.0 3.8e-07 30.0 0.0 2.9 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain RuvB_N PF05496.12 EAQ92216.1 - 3.3e-05 23.7 0.0 9.8e-05 22.1 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_lid_3 PF17862.1 EAQ92216.1 - 0.00014 21.6 0.0 0.006 16.4 0.0 2.8 2 0 0 2 2 2 1 AAA+ lid domain AAA_22 PF13401.6 EAQ92216.1 - 0.00014 22.1 1.0 0.0011 19.2 0.1 2.7 2 1 1 3 3 2 1 AAA domain TIP49 PF06068.13 EAQ92216.1 - 0.00051 19.4 0.0 0.001 18.4 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain IstB_IS21 PF01695.17 EAQ92216.1 - 0.0014 18.4 0.0 0.0066 16.2 0.0 1.9 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_5 PF07728.14 EAQ92216.1 - 0.0026 17.8 0.1 0.0093 16.0 0.0 2.1 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EAQ92216.1 - 0.0034 17.8 0.3 0.0034 17.8 0.3 2.9 3 1 0 3 3 2 1 AAA ATPase domain DUF815 PF05673.13 EAQ92216.1 - 0.0038 16.4 0.0 0.0078 15.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Mg_chelatase PF01078.21 EAQ92216.1 - 0.0047 16.3 0.5 0.01 15.2 0.1 1.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_2 PF07724.14 EAQ92216.1 - 0.005 17.0 0.0 0.01 16.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.6 EAQ92216.1 - 0.014 15.4 0.0 0.11 12.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EAQ92216.1 - 0.02 15.1 0.0 0.053 13.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EAQ92216.1 - 0.054 14.0 0.0 0.18 12.4 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAQ92216.1 - 0.062 12.9 0.0 0.18 11.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EAQ92216.1 - 0.064 13.0 0.0 0.24 11.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 EAQ92216.1 - 0.079 13.3 0.1 0.44 10.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EAQ92216.1 - 0.094 12.2 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region NACHT PF05729.12 EAQ92216.1 - 0.1 12.5 0.0 0.28 11.1 0.0 1.8 1 0 0 1 1 1 0 NACHT domain AAA_28 PF13521.6 EAQ92216.1 - 0.13 12.5 1.0 1.1 9.5 0.1 2.7 3 0 0 3 3 3 0 AAA domain Sigma54_activat PF00158.26 EAQ92216.1 - 0.18 11.5 0.0 0.51 10.0 0.0 1.8 1 0 0 1 1 1 0 Sigma-54 interaction domain COG6 PF06419.11 EAQ92217.1 - 1.2e-213 710.9 11.5 1.4e-213 710.6 11.5 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 Alpha-mann_mid PF09261.11 EAQ92217.1 - 0.014 15.5 0.0 0.092 12.9 0.0 2.5 1 0 0 1 1 1 0 Alpha mannosidase middle domain Med30 PF11315.8 EAQ92217.1 - 0.032 14.4 3.0 1.1 9.4 0.2 2.7 2 0 0 2 2 2 0 Mediator complex subunit 30 DASH_Dad3 PF08656.10 EAQ92217.1 - 0.065 13.3 1.8 0.19 11.8 0.1 2.7 3 0 0 3 3 3 0 DASH complex subunit Dad3 DASH_Duo1 PF08651.10 EAQ92217.1 - 0.065 13.0 0.2 0.32 10.8 0.2 2.2 1 0 0 1 1 1 0 DASH complex subunit Duo1 TBK1_CCD1 PF18394.1 EAQ92217.1 - 0.072 12.6 2.9 0.11 12.0 1.0 2.1 2 0 0 2 2 2 0 TANK-binding kinase 1 coiled-coil domain 1 Seryl_tRNA_N PF02403.22 EAQ92217.1 - 1 9.6 7.4 0.26 11.5 1.3 2.9 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Laminin_II PF06009.12 EAQ92217.1 - 4.5 7.3 6.9 0.6 10.1 0.6 2.8 3 0 0 3 3 3 0 Laminin Domain II APG9 PF04109.16 EAQ92218.1 - 8e-123 411.0 19.9 1.2e-49 169.7 4.2 4.0 1 1 3 4 4 4 4 Autophagy protein Apg9 Mito_carr PF00153.27 EAQ92219.1 - 3.1e-67 222.5 6.2 1.3e-23 82.7 0.2 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EAQ92219.1 - 0.0006 19.1 5.1 0.39 9.8 5.1 3.0 1 1 0 1 1 1 1 Gammaproteobacterial serine protease DnaJ PF00226.31 EAQ92220.1 - 2e-21 75.9 3.1 4.2e-21 74.8 1.6 2.5 2 0 0 2 2 2 1 DnaJ domain TPR_2 PF07719.17 EAQ92220.1 - 4e-10 39.0 11.7 0.19 11.9 0.0 7.2 6 1 0 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 EAQ92220.1 - 8.9e-10 38.6 5.4 0.44 11.5 0.0 5.6 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_9 PF13371.6 EAQ92220.1 - 9.7e-10 38.5 1.4 2.6e-05 24.3 0.3 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 EAQ92220.1 - 8.7e-09 34.8 5.6 0.0012 18.6 0.0 6.1 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_8 PF13181.6 EAQ92220.1 - 7.6e-06 25.7 5.1 0.44 10.9 0.0 6.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 EAQ92220.1 - 1.4e-05 25.5 3.3 0.6 10.6 0.1 4.9 2 1 2 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 EAQ92220.1 - 2.1e-05 25.1 3.1 0.67 10.6 0.3 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 EAQ92220.1 - 0.00027 21.2 12.6 1.2 9.5 2.3 5.0 2 2 2 4 4 4 1 Tetratricopeptide repeat BTAD PF03704.17 EAQ92220.1 - 0.0013 19.2 7.3 0.41 11.1 0.0 4.0 2 2 2 4 4 4 2 Bacterial transcriptional activator domain TPR_11 PF13414.6 EAQ92220.1 - 0.0068 16.1 0.0 0.62 9.8 0.0 3.4 2 1 1 3 3 3 1 TPR repeat TPR_7 PF13176.6 EAQ92220.1 - 0.024 14.6 4.4 4.7 7.5 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat IFT46_B_C PF12317.8 EAQ92220.1 - 0.1 12.3 0.6 0.17 11.6 0.0 1.6 2 0 0 2 2 2 0 Intraflagellar transport complex B protein 46 C terminal TPR_6 PF13174.6 EAQ92220.1 - 0.28 11.9 10.7 11 6.9 0.0 6.3 7 1 1 8 8 8 0 Tetratricopeptide repeat Gar1 PF04410.14 EAQ92221.1 - 5.2e-39 133.5 0.0 6.8e-39 133.1 0.0 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region Prominin PF05478.11 EAQ92222.1 - 0.0082 14.2 0.3 0.012 13.6 0.3 1.2 1 0 0 1 1 1 1 Prominin DUF5098 PF17023.5 EAQ92222.1 - 0.17 10.8 0.8 0.25 10.3 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5098) Baculo_PEP_C PF04513.12 EAQ92222.1 - 0.52 10.3 1.9 0.6 10.1 0.3 1.8 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Tup_N PF08581.10 EAQ92222.1 - 7.4 7.0 7.6 8.4 6.8 0.1 3.3 3 0 0 3 3 3 0 Tup N-terminal EMG1 PF03587.14 EAQ92224.1 - 3.1e-78 261.9 0.0 3.6e-78 261.7 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase Cys_Met_Meta_PP PF01053.20 EAQ92226.1 - 1.2e-30 106.4 0.0 1.6e-30 105.9 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 EAQ92226.1 - 0.013 14.7 0.0 0.022 14.0 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II SPX PF03105.19 EAQ92227.1 - 1.1e-38 134.2 4.7 2.6e-25 90.2 1.2 2.1 1 1 1 2 2 2 2 SPX domain DnaJ PF00226.31 EAQ92228.1 - 1.3e-22 79.6 0.2 1.3e-22 79.6 0.2 2.2 2 0 0 2 2 2 1 DnaJ domain zf-C2H2_jaz PF12171.8 EAQ92228.1 - 2.3e-11 43.7 3.4 5e-11 42.6 3.4 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EAQ92228.1 - 6.5e-10 39.1 2.3 2.1e-09 37.4 2.3 1.9 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 EAQ92228.1 - 4.6e-05 23.7 4.0 0.00013 22.3 1.0 2.3 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 EAQ92228.1 - 0.0015 19.2 1.2 0.047 14.5 0.2 2.8 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2 PF00096.26 EAQ92228.1 - 0.0041 17.5 4.1 0.053 14.0 0.5 2.6 2 0 0 2 2 2 1 Zinc finger, C2H2 type Actin_micro PF17003.5 EAQ92228.1 - 0.021 14.0 0.0 0.026 13.7 0.0 1.2 1 0 0 1 1 1 0 Putative actin-like family zf-C2H2_6 PF13912.6 EAQ92228.1 - 0.29 11.2 1.1 0.63 10.1 1.1 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger Myc_N PF01056.18 EAQ92228.1 - 3 7.7 12.0 0.33 10.8 6.8 1.9 2 0 0 2 2 2 0 Myc amino-terminal region Peptidase_C54 PF03416.19 EAQ92229.1 - 4.8e-76 255.8 0.0 4.7e-46 157.4 0.0 2.1 1 1 1 2 2 2 2 Peptidase family C54 R3H PF01424.22 EAQ92230.1 - 9.5e-14 51.1 0.0 2e-13 50.1 0.0 1.6 1 0 0 1 1 1 1 R3H domain G-patch PF01585.23 EAQ92230.1 - 7.1e-11 41.8 3.6 1.4e-10 40.8 3.6 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 EAQ92230.1 - 0.091 12.9 4.0 0.19 11.8 2.2 2.3 2 0 0 2 2 2 0 G-patch domain Histone PF00125.24 EAQ92231.1 - 1.3e-20 74.1 1.9 1.7e-20 73.7 1.9 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EAQ92231.1 - 4.5e-05 23.7 0.0 0.0001 22.5 0.0 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 EAQ92231.1 - 0.00025 21.5 0.0 0.00043 20.7 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A DUF1018 PF06252.12 EAQ92231.1 - 0.042 14.8 0.3 0.071 14.1 0.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1018) RP-C PF03428.13 EAQ92231.1 - 0.06 13.0 0.1 0.14 11.8 0.1 1.6 1 1 0 1 1 1 0 Replication protein C N-terminal domain Histone_H2A_C PF16211.5 EAQ92232.1 - 9.5e-22 76.4 3.1 1.4e-21 75.9 3.1 1.3 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 EAQ92232.1 - 0.0028 18.0 0.0 0.0039 17.5 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Complex1_LYR PF05347.15 EAQ92233.1 - 1.1e-08 35.0 0.6 1.4e-08 34.7 0.6 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) 2-oxoacid_dh PF00198.23 EAQ92234.1 - 1.1e-78 263.9 0.0 1.8e-78 263.2 0.0 1.3 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 EAQ92234.1 - 6.5e-17 61.1 1.1 1.2e-16 60.2 1.1 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme HlyD_3 PF13437.6 EAQ92234.1 - 0.00049 20.8 0.2 0.51 11.1 0.0 2.4 1 1 1 2 2 2 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 EAQ92234.1 - 0.0024 17.7 0.1 0.29 11.0 0.0 2.4 1 1 1 2 2 2 2 Biotin-lipoyl like DUF3614 PF12267.8 EAQ92234.1 - 0.045 14.3 0.1 0.25 11.8 0.0 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF3614) CCDC53 PF10152.9 EAQ92234.1 - 0.49 10.8 4.6 0.83 10.1 4.6 1.4 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex DUF2981 PF11200.8 EAQ92234.1 - 0.55 9.9 6.0 0.88 9.3 6.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) DUF4674 PF15719.5 EAQ92234.1 - 0.62 10.1 7.8 0.88 9.6 7.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4674) AA_permease PF00324.21 EAQ92235.1 - 2.3e-23 82.6 11.6 9.5e-23 80.5 11.6 1.7 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EAQ92235.1 - 1.4e-07 30.8 7.2 1.9e-07 30.3 7.2 1.2 1 0 0 1 1 1 1 Amino acid permease DDE_1 PF03184.19 EAQ92238.1 - 7e-28 97.4 0.0 1.4e-27 96.5 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 EAQ92238.1 - 2e-09 37.3 0.0 5.4e-09 36.0 0.0 1.8 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.16 EAQ92238.1 - 9.5e-09 34.9 0.3 2e-08 33.9 0.3 1.6 1 0 0 1 1 1 1 helix-turn-helix, Psq domain DDE_3 PF13358.6 EAQ92238.1 - 0.0098 15.6 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_1 PF03184.19 EAQ92239.1 - 7.2e-19 68.1 0.0 4.8e-18 65.4 0.0 2.0 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_psq PF05225.16 EAQ92239.1 - 9.5e-09 34.9 0.0 1.7e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 helix-turn-helix, Psq domain DDE_3 PF13358.6 EAQ92239.1 - 0.035 13.9 0.0 0.097 12.4 0.0 1.7 1 1 1 2 2 2 0 DDE superfamily endonuclease TH1 PF04858.13 EAQ92239.1 - 0.069 11.8 0.0 0.099 11.3 0.0 1.2 1 0 0 1 1 1 0 TH1 protein zf-RVT PF13966.6 EAQ92241.1 - 0.0098 16.6 0.0 0.016 15.9 0.0 1.3 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase DDE_1 PF03184.19 EAQ92242.1 - 5.2e-07 29.5 0.0 7.5e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease RasGEF_N PF00618.20 EAQ92242.1 - 0.057 13.7 0.1 1.5 9.1 0.0 2.0 2 0 0 2 2 2 0 RasGEF N-terminal motif DDE_1 PF03184.19 EAQ92243.1 - 1.3e-13 51.0 0.0 2.2e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.16 EAQ92243.1 - 1.5e-08 34.2 0.1 2.6e-08 33.5 0.1 1.4 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.16 EAQ92243.1 - 0.0011 19.0 0.6 0.0026 17.7 0.0 2.0 2 1 1 3 3 3 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.6 EAQ92243.1 - 0.094 12.5 0.0 0.62 9.8 0.0 2.0 1 1 1 2 2 2 0 DDE superfamily endonuclease CENP-B_N PF04218.13 EAQ92243.1 - 0.13 11.9 0.1 0.39 10.4 0.1 1.8 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain MLTR_LBD PF17765.1 EAQ92245.1 - 0.04 14.0 0.1 0.067 13.3 0.1 1.4 1 0 0 1 1 1 0 MmyB-like transcription regulator ligand binding domain RT_RNaseH PF17917.1 EAQ92245.1 - 0.11 12.8 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase Helitron_like_N PF14214.6 EAQ92246.1 - 2.2e-37 129.2 1.5 3.6e-37 128.5 1.5 1.4 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus DDE_1 PF03184.19 EAQ92247.1 - 1.1e-13 51.3 0.0 1.7e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 EAQ92247.1 - 0.00084 19.3 0.6 0.0022 18.0 0.0 2.0 2 1 1 3 3 3 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.6 EAQ92247.1 - 0.069 12.9 0.0 0.52 10.1 0.0 2.0 1 1 1 2 2 2 0 DDE superfamily endonuclease HTH_psq PF05225.16 EAQ92248.1 - 2e-05 24.2 0.0 3.8e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 helix-turn-helix, Psq domain DDE_1 PF03184.19 EAQ92249.1 - 5.4e-15 55.5 0.0 7.8e-15 55.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 EAQ92249.1 - 0.046 13.5 0.0 0.092 12.5 0.0 1.6 1 0 0 1 1 1 0 DDE superfamily endonuclease RasGEF_N PF00618.20 EAQ92249.1 - 0.15 12.3 0.1 3.1 8.1 0.0 2.2 2 0 0 2 2 2 0 RasGEF N-terminal motif HTH_psq PF05225.16 EAQ92251.1 - 5.7e-06 26.0 0.0 1.2e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 helix-turn-helix, Psq domain WASH_WAHD PF11945.8 EAQ92251.1 - 0.061 12.8 4.3 0.086 12.4 4.3 1.2 1 0 0 1 1 1 0 WAHD domain of WASH complex Jnk-SapK_ap_N PF09744.9 EAQ92251.1 - 0.13 12.5 5.5 0.071 13.3 3.2 1.7 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 RVT_1 PF00078.27 EAQ92252.1 - 1.4e-47 162.1 0.0 2e-47 161.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF680 PF05079.12 EAQ92254.1 - 0.05 14.3 0.0 0.11 13.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF680) Sulfate_transp PF00916.20 EAQ92256.1 - 1.8e-85 287.0 13.4 2.4e-85 286.6 13.4 1.2 1 0 0 1 1 1 1 Sulfate permease family MotB_plug PF13677.6 EAQ92256.1 - 0.19 11.3 1.1 0.46 10.1 1.1 1.5 1 0 0 1 1 1 0 Membrane MotB of proton-channel complex MotA/MotB SKG6 PF08693.10 EAQ92256.1 - 5.7 6.4 10.1 5.7 6.4 2.8 3.1 2 0 0 2 2 2 0 Transmembrane alpha-helix domain GST_C_3 PF14497.6 EAQ92257.1 - 1.9e-31 108.2 0.0 3.4e-31 107.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EAQ92257.1 - 7.8e-06 26.0 0.0 1.3e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EAQ92257.1 - 0.00047 20.1 0.0 0.00082 19.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EAQ92257.1 - 0.019 15.3 0.1 0.8 10.1 0.0 2.9 2 1 0 2 2 2 0 Glutathione S-transferase, N-terminal domain EntA_Immun PF08951.10 EAQ92259.1 - 0.013 15.9 0.2 0.019 15.3 0.2 1.2 1 0 0 1 1 1 0 Enterocin A Immunity Claudin_2 PF13903.6 EAQ92259.1 - 0.16 11.7 3.6 0.27 11.0 3.6 1.3 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Raptor_N PF14538.6 EAQ92260.1 - 0.18 11.7 0.0 0.44 10.5 0.0 1.6 1 0 0 1 1 1 0 Raptor N-terminal CASPase like domain zf-C2H2 PF00096.26 EAQ92260.1 - 8.5 7.1 9.6 11 6.7 0.3 3.2 3 0 0 3 3 3 0 Zinc finger, C2H2 type Fungal_trans_2 PF11951.8 EAQ92261.1 - 1.9e-12 46.7 0.0 6.8e-12 44.9 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Patatin PF01734.22 EAQ92263.1 - 4.1e-13 50.0 0.0 2.2e-12 47.6 0.0 2.0 1 1 0 1 1 1 1 Patatin-like phospholipase DUF4449 PF14613.6 EAQ92264.1 - 1e-05 25.7 1.9 2.4e-05 24.5 0.1 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF4449) AbiH PF14253.6 EAQ92264.1 - 0.071 13.0 0.3 0.15 11.9 0.1 1.6 2 0 0 2 2 2 0 Bacteriophage abortive infection AbiH DUF445 PF04286.12 EAQ92264.1 - 0.32 10.8 3.5 1 9.1 3.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF445) YpzI PF14140.6 EAQ92266.1 - 1.2 9.0 11.5 15 5.5 0.2 4.0 4 0 0 4 4 4 0 YpzI-like protein WD40 PF00400.32 EAQ92267.1 - 1.2e-18 67.1 14.5 2.2e-06 28.3 0.1 5.9 6 1 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAQ92267.1 - 3.2e-07 30.5 0.2 0.042 14.2 0.0 3.8 3 2 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EAQ92267.1 - 0.0049 15.6 0.0 1.8 7.1 0.0 3.2 4 0 0 4 4 4 2 Nucleoporin Nup120/160 UAF_Rrn10 PF05234.11 EAQ92268.1 - 0.16 12.2 0.0 0.78 10.0 0.0 2.0 1 1 0 1 1 1 0 UAF complex subunit Rrn10 Zn_clus PF00172.18 EAQ92270.1 - 5.1e-07 29.7 13.6 7.7e-07 29.1 13.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain APG5 PF04106.12 EAQ92271.1 - 2.3e-46 158.2 0.0 6.4e-46 156.8 0.0 1.6 1 1 0 1 1 1 1 Autophagy protein Apg5 DUF4611 PF15387.6 EAQ92273.1 - 8.1 6.7 9.4 2.6 8.3 0.1 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) ORMDL PF04061.14 EAQ92275.1 - 3.7e-58 195.2 2.5 4.3e-58 194.9 2.5 1.0 1 0 0 1 1 1 1 ORMDL family Macoilin PF09726.9 EAQ92277.1 - 0.11 11.0 4.4 0.18 10.3 4.4 1.3 1 0 0 1 1 1 0 Macoilin family CDC45 PF02724.14 EAQ92277.1 - 0.22 9.8 18.3 0.31 9.3 18.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Apt1 PF10351.9 EAQ92277.1 - 0.39 9.5 9.5 0.65 8.8 9.5 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain Response_reg PF00072.24 EAQ92278.1 - 1.1e-27 96.4 0.2 1.9e-27 95.6 0.2 1.4 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 EAQ92278.1 - 5.8e-27 94.4 0.0 6.2e-25 87.9 0.0 2.7 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EAQ92278.1 - 7.9e-15 54.6 0.0 1.7e-14 53.6 0.0 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 EAQ92278.1 - 0.0051 17.2 0.0 0.048 14.1 0.0 2.3 2 0 0 2 2 2 1 HAMP domain NBP1 PF08537.10 EAQ92278.1 - 0.033 13.6 1.4 0.065 12.6 1.4 1.4 1 0 0 1 1 1 0 Fungal Nap binding protein NBP1 CMD PF02627.20 EAQ92279.1 - 1.3e-07 31.6 0.3 6.6e-07 29.3 0.1 2.0 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family Guanylin PF02058.15 EAQ92279.1 - 0.077 13.5 0.9 0.14 12.6 0.1 1.8 2 1 0 2 2 2 0 Guanylin precursor DUF3253 PF11625.8 EAQ92279.1 - 0.079 13.2 0.2 0.15 12.3 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3253) Pkinase PF00069.25 EAQ92281.1 - 3.9e-09 36.3 0.0 6e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 EAQ92281.1 - 7e-08 32.7 0.2 0.0042 17.0 0.0 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 EAQ92281.1 - 1.6e-07 30.9 0.0 2.2e-06 27.2 0.0 2.1 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EAQ92281.1 - 0.00034 20.3 0.0 0.0038 16.9 0.0 2.4 2 1 0 2 2 2 1 RIO1 family Pkinase_Tyr PF07714.17 EAQ92281.1 - 0.0062 15.9 0.0 0.0077 15.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EAQ92281.1 - 0.026 13.3 0.0 0.035 12.9 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase DUF1679 PF07914.11 EAQ92281.1 - 0.28 10.0 0.0 1.4 7.7 0.0 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1679) Aldo_ket_red PF00248.21 EAQ92282.1 - 2e-09 37.0 0.0 2.7e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family SLH PF00395.20 EAQ92282.1 - 0.013 15.5 0.3 1.2 9.2 0.0 2.6 2 0 0 2 2 2 0 S-layer homology domain Clat_adaptor_s PF01217.20 EAQ92283.1 - 8.2e-41 139.3 0.3 1.1e-40 138.9 0.3 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain PulA_N1 PF17999.1 EAQ92283.1 - 0.015 16.0 0.1 0.022 15.5 0.1 1.3 1 0 0 1 1 1 0 Pullulanase N1-terminal domain Maf1 PF09174.10 EAQ92284.1 - 2.5e-49 167.8 0.0 3.6e-49 167.3 0.0 1.2 1 0 0 1 1 1 1 Maf1 regulator PP2C PF00481.21 EAQ92285.1 - 5.4e-82 275.3 0.8 7.2e-82 274.9 0.0 1.4 2 0 0 2 2 2 1 Protein phosphatase 2C He_PIG PF05345.12 EAQ92286.1 - 2.4e-10 40.4 11.7 0.0025 18.0 0.3 4.3 4 0 0 4 4 4 3 Putative Ig domain DUF4381 PF14316.6 EAQ92286.1 - 0.18 12.0 0.1 0.35 11.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Methyltransf_16 PF10294.9 EAQ92287.1 - 5.7e-46 156.4 0.0 7.1e-46 156.1 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 EAQ92287.1 - 0.16 11.5 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain CAP_N PF01213.19 EAQ92288.1 - 0.026 14.0 2.8 0.12 11.8 3.4 1.7 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.11 EAQ92288.1 - 0.25 11.4 0.1 0.25 11.4 0.1 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator DUF1712 PF08217.11 EAQ92289.1 - 1.8e-13 49.9 0.0 1.3e-09 37.1 0.0 2.9 2 1 0 2 2 2 2 Fungal domain of unknown function (DUF1712) KH_1 PF00013.29 EAQ92290.1 - 0.13 12.1 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 KH domain Exo70 PF03081.15 EAQ92290.1 - 0.18 10.8 0.0 0.3 10.1 0.0 1.3 1 0 0 1 1 1 0 Exo70 exocyst complex subunit Pex24p PF06398.11 EAQ92291.1 - 2.4e-05 23.5 2.6 3.6e-05 22.9 2.6 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Apolipoprotein PF01442.18 EAQ92292.1 - 0.0093 15.9 1.1 0.012 15.5 1.1 1.1 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain TRAF_BIRC3_bd PF16673.5 EAQ92292.1 - 0.019 14.8 0.2 0.039 13.7 0.2 1.5 1 0 0 1 1 1 0 TNF receptor-associated factor BIRC3 binding domain Enolase_N PF03952.16 EAQ92292.1 - 0.054 13.7 0.3 0.07 13.3 0.3 1.2 1 0 0 1 1 1 0 Enolase, N-terminal domain Metal_resist PF13801.6 EAQ92292.1 - 0.067 13.4 0.1 0.082 13.1 0.1 1.1 1 0 0 1 1 1 0 Heavy-metal resistance V-ATPase_G_2 PF16999.5 EAQ92292.1 - 0.12 12.8 5.6 0.16 12.4 3.1 1.9 1 1 1 2 2 2 0 Vacuolar (H+)-ATPase G subunit SNARE PF05739.19 EAQ92292.1 - 0.56 10.2 1.4 0.97 9.5 0.8 1.6 1 1 1 2 2 2 0 SNARE domain ETRAMP PF09716.10 EAQ92292.1 - 5 7.3 7.3 22 5.2 1.7 2.6 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) PRP1_N PF06424.12 EAQ92293.1 - 1.9e-47 161.4 7.9 1.9e-47 161.4 7.9 2.4 3 0 0 3 3 3 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.6 EAQ92293.1 - 4.7e-29 98.6 45.4 0.00023 21.7 0.0 13.8 4 3 10 14 14 14 10 Tetratricopeptide repeat TPR_19 PF14559.6 EAQ92293.1 - 2.7e-24 85.4 33.3 8.4e-06 26.2 0.4 9.8 8 2 2 10 10 9 6 Tetratricopeptide repeat TPR_16 PF13432.6 EAQ92293.1 - 7.4e-12 45.7 33.4 9.1e-05 23.0 0.0 8.8 7 1 1 9 9 9 3 Tetratricopeptide repeat TPR_2 PF07719.17 EAQ92293.1 - 1.1e-07 31.4 21.6 0.55 10.5 0.1 11.1 12 1 1 13 13 12 2 Tetratricopeptide repeat TPR_8 PF13181.6 EAQ92293.1 - 3.1e-07 30.1 2.9 0.6 10.5 0.0 7.0 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_15 PF13429.6 EAQ92293.1 - 2e-05 24.0 22.9 0.0017 17.6 1.5 5.0 2 2 2 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 EAQ92293.1 - 4.2e-05 23.6 7.9 26 5.5 0.0 9.2 10 2 2 12 12 12 0 Tetratricopeptide repeat NARP1 PF12569.8 EAQ92293.1 - 9.6e-05 21.5 11.2 0.69 8.7 0.0 5.8 3 1 3 6 6 6 3 NMDA receptor-regulated protein 1 Suf PF05843.14 EAQ92293.1 - 0.0001 22.4 0.0 8.8 6.2 0.0 4.4 4 1 1 5 5 5 1 Suppressor of forked protein (Suf) TPR_1 PF00515.28 EAQ92293.1 - 0.0002 21.0 0.5 0.28 11.1 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 EAQ92293.1 - 0.0059 16.7 25.0 0.04 14.1 0.1 7.3 6 2 1 7 7 7 1 Tetratricopeptide repeat TPR_11 PF13414.6 EAQ92293.1 - 0.016 14.9 11.6 5.7 6.7 0.2 6.2 5 1 1 6 6 6 0 TPR repeat Wzy_C_2 PF11846.8 EAQ92293.1 - 0.098 12.6 4.3 0.62 9.9 0.5 3.5 3 0 0 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal NuDC PF16273.5 EAQ92293.1 - 5.3 7.6 13.9 1.2 9.7 5.3 2.9 2 0 0 2 2 2 0 Nuclear distribution C domain FUSC_2 PF13515.6 EAQ92294.1 - 6.4e-22 78.0 0.8 6.4e-22 78.0 0.8 2.7 2 1 0 2 2 2 1 Fusaric acid resistance protein-like ALMT PF11744.8 EAQ92294.1 - 0.00024 20.1 5.1 0.0053 15.6 0.7 3.3 4 0 0 4 4 4 2 Aluminium activated malate transporter GCV_T_C PF08669.11 EAQ92294.1 - 0.17 11.8 0.0 0.5 10.3 0.0 1.8 1 0 0 1 1 1 0 Glycine cleavage T-protein C-terminal barrel domain Inhibitor_I53 PF11714.8 EAQ92294.1 - 5.6 7.2 0.0 5.6 7.2 0.0 3.0 4 0 0 4 4 4 0 Thrombin inhibitor Madanin HAD_2 PF13419.6 EAQ92295.1 - 1.5e-11 44.7 0.0 4.7e-06 26.8 0.0 2.2 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EAQ92295.1 - 1.7e-06 28.0 0.3 3e-06 27.2 0.3 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 EAQ92295.1 - 2.4e-06 28.0 0.0 0.013 15.8 0.0 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Pkinase PF00069.25 EAQ92296.1 - 2.6e-56 190.9 0.0 3.5e-56 190.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ92296.1 - 1.5e-35 122.8 0.0 2.2e-35 122.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EAQ92296.1 - 0.00016 20.6 0.0 0.00024 20.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EAQ92296.1 - 0.00062 19.2 0.0 0.0011 18.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EAQ92296.1 - 0.025 13.5 0.0 0.033 13.1 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 EAQ92296.1 - 0.075 12.1 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 SH2_2 PF14633.6 EAQ92297.1 - 1.9e-87 292.2 0.1 1.9e-87 292.2 0.1 2.8 3 0 0 3 3 3 1 SH2 domain HTH_44 PF14641.6 EAQ92297.1 - 2.1e-36 124.8 0.7 2.1e-36 124.8 0.7 2.2 2 0 0 2 2 2 1 Helix-turn-helix DNA-binding domain of SPT6 HHH_7 PF14635.6 EAQ92297.1 - 3.1e-31 107.8 0.0 8.8e-31 106.3 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.6 EAQ92297.1 - 1e-30 106.5 0.0 7.9e-30 103.6 0.0 2.6 2 0 0 2 2 2 1 Holliday-junction resolvase-like of SPT6 SPT6_acidic PF14632.6 EAQ92297.1 - 1.1e-20 74.0 33.3 1.1e-20 74.0 33.3 7.0 3 1 4 7 7 7 1 Acidic N-terminal SPT6 HHH_9 PF17674.1 EAQ92297.1 - 1.9e-06 28.7 0.7 1.9e-06 28.7 0.7 3.5 2 1 0 2 2 2 1 HHH domain SH2 PF00017.24 EAQ92297.1 - 0.00013 22.0 0.0 0.00035 20.6 0.0 1.8 1 0 0 1 1 1 1 SH2 domain HHH_3 PF12836.7 EAQ92297.1 - 0.0002 21.5 0.0 0.00056 20.1 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif S1 PF00575.23 EAQ92297.1 - 0.00024 21.4 0.4 0.00082 19.7 0.4 2.0 1 0 0 1 1 1 1 S1 RNA binding domain Tex_YqgF PF16921.5 EAQ92297.1 - 0.027 14.9 0.0 0.35 11.3 0.0 2.5 2 0 0 2 2 2 0 Tex protein YqgF-like domain Oxysterol_BP PF01237.18 EAQ92298.1 - 5.5e-109 364.4 0.0 3.7e-108 361.7 0.0 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein PH_8 PF15409.6 EAQ92298.1 - 8.1e-39 131.8 1.7 4e-38 129.6 0.1 2.5 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 EAQ92298.1 - 1.1e-07 32.3 0.1 4.3e-07 30.4 0.0 2.0 2 0 0 2 2 2 1 PH domain PH_17 PF18012.1 EAQ92298.1 - 0.06 13.1 0.6 1.3 8.8 0.4 2.5 2 0 0 2 2 2 0 PH domain PH_11 PF15413.6 EAQ92298.1 - 0.17 12.3 0.3 14 6.2 0.3 2.8 1 1 0 1 1 1 0 Pleckstrin homology domain Hydantoinase_B PF02538.14 EAQ92299.1 - 2.2e-196 653.3 0.7 5.2e-115 384.8 0.3 2.3 1 1 1 2 2 2 2 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 EAQ92299.1 - 1.1e-103 346.5 0.6 1.1e-103 346.5 0.6 1.5 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 EAQ92299.1 - 1.2e-58 197.8 0.8 6.2e-57 192.2 0.0 2.5 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region Pkinase PF00069.25 EAQ92300.1 - 3.4e-44 151.2 0.0 5.2e-44 150.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ92300.1 - 2.3e-19 69.7 0.0 4e-19 68.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase UBA_2 PF08587.11 EAQ92300.1 - 9e-16 57.7 0.5 1.6e-15 56.9 0.5 1.4 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.6 EAQ92300.1 - 3.7e-05 23.2 0.0 5.1e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EAQ92300.1 - 0.0092 15.0 0.1 0.015 14.3 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain YukC PF10140.9 EAQ92300.1 - 0.015 14.1 0.0 0.024 13.5 0.0 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC APH PF01636.23 EAQ92300.1 - 0.047 13.6 0.3 0.11 12.4 0.3 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 EAQ92300.1 - 0.19 10.7 0.2 0.27 10.2 0.2 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DUF92 PF01940.16 EAQ92301.1 - 4.9e-87 291.3 4.1 6e-87 291.0 4.1 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF92 CPBP PF02517.16 EAQ92301.1 - 0.17 12.3 1.9 14 6.2 0.0 2.7 1 1 1 2 2 2 0 CPBP intramembrane metalloprotease Fungal_trans PF04082.18 EAQ92304.1 - 3.7e-07 29.4 2.2 3.7e-07 29.4 2.2 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain ketoacyl-synt PF00109.26 EAQ92307.1 - 5.8e-74 248.9 0.0 1.4e-73 247.6 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain SAT PF16073.5 EAQ92307.1 - 1.3e-71 241.1 0.5 5.1e-71 239.2 0.1 2.1 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Acyl_transf_1 PF00698.21 EAQ92307.1 - 1.5e-43 149.5 0.0 2.8e-43 148.7 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EAQ92307.1 - 1.6e-36 124.9 0.2 3.6e-36 123.7 0.2 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.20 EAQ92307.1 - 2.7e-24 86.6 1.0 3e-22 79.9 0.0 3.2 3 1 0 3 3 3 1 Thioesterase domain PP-binding PF00550.25 EAQ92307.1 - 2.5e-21 75.8 3.8 1.1e-10 41.7 0.1 3.1 3 0 0 3 3 3 2 Phosphopantetheine attachment site PS-DH PF14765.6 EAQ92307.1 - 2.3e-15 56.6 0.0 4.4e-15 55.7 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Thiolase_N PF00108.23 EAQ92307.1 - 0.00017 21.1 0.1 0.0032 16.9 0.1 2.3 2 0 0 2 2 2 1 Thiolase, N-terminal domain KAsynt_C_assoc PF16197.5 EAQ92307.1 - 0.00029 21.3 0.0 0.00089 19.7 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Hydrolase_4 PF12146.8 EAQ92307.1 - 0.031 13.5 0.1 0.33 10.2 0.0 2.3 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Cu-oxidase_2 PF07731.14 EAQ92308.1 - 6.7e-41 139.2 11.6 2.4e-37 127.7 1.6 3.9 3 1 0 3 3 3 3 Multicopper oxidase Cu-oxidase_3 PF07732.15 EAQ92308.1 - 1.9e-36 124.7 10.7 7.3e-34 116.3 1.0 4.1 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 EAQ92308.1 - 2.9e-20 73.0 3.5 1.1e-18 67.9 0.5 3.1 3 0 0 3 3 3 1 Multicopper oxidase Cupredoxin_1 PF13473.6 EAQ92308.1 - 0.0019 18.3 0.0 12 6.0 0.0 3.6 3 0 0 3 3 3 2 Cupredoxin-like domain PPC PF04151.15 EAQ92308.1 - 0.055 14.6 1.0 1.4 10.0 0.1 3.2 3 0 0 3 3 3 0 Bacterial pre-peptidase C-terminal domain RNase_E_G PF10150.9 EAQ92308.1 - 0.12 11.8 0.0 0.18 11.2 0.0 1.1 1 0 0 1 1 1 0 Ribonuclease E/G family DNA_pol_E_B PF04042.16 EAQ92309.1 - 7.5e-68 228.0 0.0 1.3e-67 227.2 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B PC4 PF02229.16 EAQ92310.1 - 4e-21 74.4 0.1 6.7e-21 73.7 0.1 1.4 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) Coilin_N PF15862.5 EAQ92310.1 - 5.8 6.7 10.2 4.4 7.1 1.1 2.1 2 0 0 2 2 2 0 Coilin N-terminus PXA PF02194.15 EAQ92311.1 - 9.3e-34 117.0 0.1 2e-33 115.9 0.1 1.6 1 0 0 1 1 1 1 PXA domain Nexin_C PF08628.12 EAQ92311.1 - 1e-23 84.0 2.1 2.3e-23 82.9 0.1 2.7 3 0 0 3 3 3 1 Sorting nexin C terminal PX PF00787.24 EAQ92311.1 - 2.6e-07 30.6 0.0 3.4e-06 27.0 0.0 2.4 2 0 0 2 2 2 1 PX domain MFS_1 PF07690.16 EAQ92312.1 - 1.1e-14 54.1 14.2 1.8e-14 53.4 11.5 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily ADIP PF11559.8 EAQ92313.1 - 1.3e-37 129.2 6.3 1.3e-37 129.2 6.3 2.1 2 0 0 2 2 2 1 Afadin- and alpha -actinin-Binding Golgin_A5 PF09787.9 EAQ92313.1 - 0.0014 18.1 2.5 0.0039 16.7 2.5 1.7 1 0 0 1 1 1 1 Golgin subfamily A member 5 TPR_MLP1_2 PF07926.12 EAQ92313.1 - 0.19 11.8 15.8 0.024 14.7 10.4 2.3 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein SelP_N PF04592.14 EAQ92313.1 - 0.58 9.5 2.3 1.4 8.3 0.0 2.3 2 0 0 2 2 2 0 Selenoprotein P, N terminal region Fez1 PF06818.15 EAQ92313.1 - 2.5 8.5 15.7 0.1 13.1 6.8 2.7 3 0 0 3 3 3 0 Fez1 Cytochrom_B558a PF05038.13 EAQ92313.1 - 4.1 6.9 8.2 12 5.4 8.2 1.8 1 0 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit Spc7 PF08317.11 EAQ92313.1 - 4.3 6.1 7.2 12 4.7 7.2 1.7 1 0 0 1 1 1 0 Spc7 kinetochore protein RRM_Rrp7 PF17799.1 EAQ92314.1 - 1.4e-14 54.2 0.0 2.4e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 Rrp7 RRM-like N-terminal domain RRP7 PF12923.7 EAQ92314.1 - 6.3e-14 52.1 19.2 1.2e-13 51.3 19.2 1.5 1 1 0 1 1 1 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain MOSC PF03473.17 EAQ92315.1 - 3.2e-24 85.4 0.0 5.9e-24 84.5 0.0 1.5 1 0 0 1 1 1 1 MOSC domain Fer2 PF00111.27 EAQ92315.1 - 7.9e-08 32.1 4.0 1.9e-07 30.9 4.0 1.6 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain 3-alpha PF03475.14 EAQ92315.1 - 0.0016 18.3 0.0 0.003 17.4 0.0 1.5 1 0 0 1 1 1 1 3-alpha domain F-box PF00646.33 EAQ92316.1 - 0.0064 16.3 0.0 0.015 15.2 0.0 1.6 1 0 0 1 1 1 1 F-box domain BAR PF03114.18 EAQ92317.1 - 1.2e-69 234.6 6.6 1.5e-69 234.3 6.6 1.1 1 0 0 1 1 1 1 BAR domain Topoisom_I_N PF02919.15 EAQ92317.1 - 0.54 9.7 4.5 0.94 8.9 4.5 1.3 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment TMPIT PF07851.13 EAQ92317.1 - 1.3 8.2 4.7 15 4.7 0.0 2.1 1 1 1 2 2 2 0 TMPIT-like protein Aminotran_5 PF00266.19 EAQ92318.1 - 5.4e-83 279.0 0.0 2.8e-78 263.5 0.0 2.1 1 1 1 2 2 2 2 Aminotransferase class-V Beta_elim_lyase PF01212.21 EAQ92318.1 - 3.5e-07 29.8 0.0 5.6e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 EAQ92318.1 - 1.2e-06 28.1 0.0 3.7e-06 26.5 0.1 1.7 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.19 EAQ92318.1 - 0.0036 16.1 0.1 0.014 14.2 0.0 1.8 2 0 0 2 2 2 1 Pyridoxal-dependent decarboxylase conserved domain Cys_Met_Meta_PP PF01053.20 EAQ92318.1 - 0.025 13.1 0.0 0.038 12.5 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme CsbD PF05532.12 EAQ92319.1 - 3.4e-06 26.9 22.6 2.3e-05 24.2 1.7 3.2 2 1 1 3 3 3 3 CsbD-like NmrA PF05368.13 EAQ92321.1 - 2.1e-10 40.6 0.0 1.4e-09 37.9 0.0 2.1 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EAQ92321.1 - 4.4e-06 26.7 0.0 8e-05 22.6 0.0 2.3 2 0 0 2 2 2 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 EAQ92321.1 - 0.033 14.5 0.0 0.085 13.1 0.0 1.7 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain LPD22 PF18834.1 EAQ92321.1 - 0.041 14.1 0.0 0.23 11.7 0.0 2.2 2 1 0 2 2 2 0 Large polyvalent protein associated domain 22 A_deaminase PF00962.22 EAQ92322.1 - 2.3e-08 33.8 0.0 9.7e-08 31.7 0.0 2.0 3 0 0 3 3 3 1 Adenosine/AMP deaminase DAO PF01266.24 EAQ92323.1 - 2.4e-33 116.2 3.4 3.1e-33 115.8 3.4 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EAQ92323.1 - 0.0052 17.0 0.9 0.011 15.9 0.9 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 EAQ92323.1 - 0.013 14.8 1.7 0.022 14.0 1.7 1.4 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.14 EAQ92323.1 - 0.61 9.3 2.7 1 8.5 2.7 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase eIF-5_eIF-2B PF01873.17 EAQ92324.1 - 9.8e-41 138.3 0.2 1.6e-40 137.6 0.2 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 zinc_ribbon_6 PF14599.6 EAQ92324.1 - 0.12 12.4 0.5 13 5.9 0.1 2.4 2 0 0 2 2 2 0 Zinc-ribbon Arc_trans_TRASH PF08394.10 EAQ92324.1 - 2.1 8.7 7.2 1.7 9.0 0.2 2.6 1 1 1 2 2 2 0 Archaeal TRASH domain PNGaseA PF12222.8 EAQ92326.1 - 3.7e-170 566.5 1.3 5e-170 566.0 1.3 1.1 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A DUF1279 PF06916.13 EAQ92327.1 - 7.7e-11 42.4 0.0 1.1e-10 41.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) AIM24 PF01987.17 EAQ92328.1 - 7.2e-52 176.1 0.1 8.7e-52 175.8 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 Ndc1_Nup PF09531.10 EAQ92328.1 - 0.031 13.0 2.3 0.029 13.1 2.3 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Pkinase PF00069.25 EAQ92332.1 - 1.1e-53 182.3 0.0 1.5e-53 181.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ92332.1 - 7e-21 74.7 0.5 1.2e-20 74.0 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 EAQ92332.1 - 0.017 15.1 0.1 0.061 13.2 0.0 1.9 3 0 0 3 3 3 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 EAQ92332.1 - 0.017 14.7 0.8 0.037 13.6 0.8 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pex24p PF06398.11 EAQ92334.1 - 1.9e-81 273.9 3.4 2.5e-54 184.7 0.0 2.1 2 0 0 2 2 2 2 Integral peroxisomal membrane peroxin polyprenyl_synt PF00348.17 EAQ92335.1 - 3.6e-45 154.0 0.0 4.2e-45 153.8 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Fez1 PF06818.15 EAQ92335.1 - 0.045 14.2 0.1 0.069 13.6 0.1 1.2 1 0 0 1 1 1 0 Fez1 CDC14 PF08045.11 EAQ92336.1 - 2e-116 388.1 0.0 2.4e-116 387.8 0.0 1.0 1 0 0 1 1 1 1 Cell division control protein 14, SIN component nec1 PF10379.9 EAQ92337.1 - 0.085 12.3 1.8 0.14 11.7 1.8 1.4 1 0 0 1 1 1 0 Virulence protein nec1 Aldedh PF00171.22 EAQ92339.1 - 1.9e-14 53.1 9.8 4.2e-09 35.4 7.1 2.7 1 1 1 2 2 2 2 Aldehyde dehydrogenase family UPF0489 PF12640.7 EAQ92339.1 - 0.15 12.3 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 UPF0489 domain Fungal_TACC PF12709.7 EAQ92340.1 - 2e-10 40.9 4.2 2e-10 40.9 4.2 3.7 4 0 0 4 4 4 2 Fungal Transforming acidic coiled-coil (TACC) proteins GIT_CC PF16559.5 EAQ92340.1 - 0.009 15.9 3.7 0.049 13.5 0.5 3.2 3 0 0 3 3 3 1 GIT coiled-coil Rho guanine nucleotide exchange factor DUF4407 PF14362.6 EAQ92340.1 - 0.056 12.8 20.9 0.31 10.4 2.8 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) KilA-N PF04383.13 EAQ92341.1 - 0.00019 21.2 0.0 0.0047 16.8 0.0 2.3 1 1 0 1 1 1 1 KilA-N domain PTCB-BRCT PF12738.7 EAQ92344.1 - 3.1e-06 27.0 0.1 2e-05 24.4 0.0 2.0 2 0 0 2 2 2 1 twin BRCT domain BRCT_2 PF16589.5 EAQ92344.1 - 0.00036 20.9 0.0 0.00054 20.3 0.0 1.4 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 EAQ92344.1 - 0.0026 18.1 0.0 0.0039 17.5 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AMP-binding PF00501.28 EAQ92345.1 - 3.8e-73 246.5 0.0 5.1e-73 246.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 EAQ92345.1 - 4e-19 68.3 1.4 6.5e-19 67.6 0.4 2.0 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 EAQ92345.1 - 1.7e-17 64.2 0.6 3.8e-16 59.8 0.0 2.4 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Stn1_C PF12659.7 EAQ92345.1 - 0.16 12.0 0.0 0.28 11.1 0.0 1.3 1 0 0 1 1 1 0 Telomere capping C-terminal wHTH ADH_zinc_N PF00107.26 EAQ92347.1 - 3.4e-22 78.8 0.0 4.5e-22 78.4 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EAQ92347.1 - 6.2e-22 79.1 0.1 1.2e-09 39.3 0.0 2.3 1 1 1 2 2 2 2 Zinc-binding dehydrogenase ADH_N PF08240.12 EAQ92347.1 - 1.8e-06 27.8 0.0 3.8e-06 26.7 0.0 1.6 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain DLH PF01738.18 EAQ92348.1 - 6.1e-15 55.4 0.1 1.9e-12 47.2 0.1 2.6 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 EAQ92348.1 - 0.012 15.5 0.0 0.034 14.0 0.0 1.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold RuBisCO_large_N PF02788.16 EAQ92348.1 - 0.15 12.2 0.1 0.5 10.6 0.0 1.8 2 0 0 2 2 2 0 Ribulose bisphosphate carboxylase large chain, N-terminal domain Abhydrolase_1 PF00561.20 EAQ92348.1 - 0.16 11.6 0.1 1.8 8.2 0.1 2.4 1 1 1 2 2 2 0 alpha/beta hydrolase fold LAT PF15234.6 EAQ92348.1 - 0.87 9.3 6.9 4.7 6.9 0.0 2.2 2 0 0 2 2 2 0 Linker for activation of T-cells CDT1_C PF16679.5 EAQ92349.1 - 3.8e-22 78.5 0.5 3.8e-22 78.5 0.5 2.1 3 0 0 3 3 3 1 DNA replication factor Cdt1 C-terminal domain MBF1 PF08523.10 EAQ92350.1 - 1.3e-23 83.2 1.8 2.8e-23 82.2 1.8 1.6 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 EAQ92350.1 - 3.1e-11 43.1 0.0 5.6e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 EAQ92350.1 - 4.3e-05 23.8 0.0 6.6e-05 23.2 0.0 1.6 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 EAQ92350.1 - 0.022 14.8 0.0 0.038 14.0 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain DUF1365 PF07103.11 EAQ92351.1 - 3e-64 217.0 0.2 3.9e-64 216.6 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1365) GFA PF04828.14 EAQ92352.1 - 2.1e-13 50.4 0.0 2.6e-13 50.1 0.0 1.1 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Glyco_hydro_18 PF00704.28 EAQ92353.1 - 1.5e-07 31.5 0.0 2.2e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 INO80_Ies4 PF08193.11 EAQ92355.1 - 2.4e-82 276.6 23.1 3e-82 276.2 23.1 1.1 1 0 0 1 1 1 1 INO80 complex subunit Ies4 SPRY PF00622.28 EAQ92357.1 - 1.1e-16 61.1 0.0 2.4e-16 60.0 0.0 1.5 1 0 0 1 1 1 1 SPRY domain CLTH PF10607.9 EAQ92357.1 - 3e-14 53.2 0.0 8.1e-14 51.7 0.0 1.7 1 1 1 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 EAQ92357.1 - 1.5e-05 24.7 0.0 3.4e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 LisH GST_N_4 PF17172.4 EAQ92358.1 - 3.2e-18 66.3 0.0 7.4e-18 65.1 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 EAQ92358.1 - 1.2e-07 31.4 0.0 2.6e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 EAQ92358.1 - 2e-07 31.4 0.0 3.9e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein SAM35 PF10806.8 EAQ92358.1 - 0.00017 21.8 0.0 0.00032 20.9 0.0 1.5 1 0 0 1 1 1 1 SAM35, subunit of SAM coomplex GST_C_2 PF13410.6 EAQ92358.1 - 0.0005 20.0 0.0 0.0013 18.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain adh_short PF00106.25 EAQ92360.1 - 7.8e-15 54.8 0.0 3.1e-14 52.9 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EAQ92360.1 - 2.2e-10 40.5 0.0 3.1e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EAQ92360.1 - 0.035 14.0 0.0 0.047 13.6 0.0 1.2 1 0 0 1 1 1 0 KR domain Chitin_synth_1 PF01644.17 EAQ92361.1 - 3.5e-69 231.9 0.0 5.7e-69 231.3 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 EAQ92361.1 - 1.7e-27 95.1 0.1 3e-27 94.4 0.1 1.4 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 EAQ92361.1 - 1.1e-25 90.3 0.1 1.4e-21 76.7 0.0 2.4 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 EAQ92361.1 - 1.9e-05 24.7 11.2 1.9e-05 24.7 11.2 3.2 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Ras PF00071.22 EAQ92366.1 - 7.4e-51 172.0 0.0 1.4e-50 171.1 0.0 1.4 1 1 0 1 1 1 1 Ras family Roc PF08477.13 EAQ92366.1 - 4.9e-18 65.5 0.0 7.5e-17 61.7 0.0 2.1 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAQ92366.1 - 0.00055 19.4 0.0 0.0014 18.1 0.0 1.7 1 1 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EAQ92366.1 - 0.028 14.3 0.0 9.2 6.1 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 EAQ92366.1 - 0.07 13.5 0.0 0.13 12.6 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain FeoB_N PF02421.18 EAQ92366.1 - 0.075 12.6 0.0 1.2 8.7 0.0 2.3 2 1 0 2 2 2 0 Ferrous iron transport protein B AAA_25 PF13481.6 EAQ92366.1 - 0.14 11.7 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.10 EAQ92366.1 - 0.19 11.1 0.0 1.4 8.3 0.0 2.0 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Hydrolase PF00702.26 EAQ92368.1 - 4.6e-08 33.6 0.0 7.4e-08 32.9 0.0 1.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EAQ92368.1 - 6.8e-07 29.5 0.0 1.1e-06 28.8 0.0 1.4 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EAQ92368.1 - 2.5e-05 24.2 0.0 6.6e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like Mcp5_PH PF12814.7 EAQ92370.1 - 4.3e-46 156.0 0.0 8.1e-46 155.1 0.0 1.5 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology Fez1 PF06818.15 EAQ92370.1 - 0.0015 19.1 16.9 0.0031 18.0 16.9 1.4 1 0 0 1 1 1 1 Fez1 YkyA PF10368.9 EAQ92370.1 - 0.13 11.9 17.0 0.019 14.6 10.0 2.1 2 0 0 2 2 2 0 Putative cell-wall binding lipoprotein FmiP_Thoc5 PF09766.9 EAQ92370.1 - 0.14 11.4 7.0 0.79 9.0 1.2 2.6 3 0 0 3 3 3 0 Fms-interacting protein/Thoc5 IRF PF00605.17 EAQ92370.1 - 0.51 10.7 3.2 0.99 9.7 3.2 1.4 1 0 0 1 1 1 0 Interferon regulatory factor transcription factor DUF3584 PF12128.8 EAQ92370.1 - 0.86 7.0 15.0 1.3 6.5 15.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) GAS PF13851.6 EAQ92370.1 - 1 8.7 16.0 1.9 7.8 16.0 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DivIC PF04977.15 EAQ92370.1 - 4.1 7.2 5.4 4.4 7.2 0.0 2.4 1 1 1 2 2 2 0 Septum formation initiator PALP PF00291.25 EAQ92371.1 - 1.1e-07 31.6 0.0 1.4e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme IDO PF01231.18 EAQ92372.1 - 7.4e-07 28.3 0.0 8.2e-07 28.2 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase SpoU_methylase PF00588.19 EAQ92374.1 - 2.4e-27 95.8 0.0 3.9e-27 95.2 0.0 1.3 1 0 0 1 1 1 1 SpoU rRNA Methylase family zf-PHD-like PF15446.6 EAQ92375.1 - 1.1e-70 236.7 16.0 2.1e-70 235.7 16.0 1.6 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain SNF2_N PF00176.23 EAQ92375.1 - 5.9e-50 169.9 0.2 1.6e-49 168.5 0.2 1.6 1 1 1 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EAQ92375.1 - 4.1e-18 65.7 0.0 2.6e-17 63.2 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EAQ92375.1 - 2e-05 24.7 0.0 3.6e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 EAQ92375.1 - 3.2e-05 23.2 0.3 7.5e-05 22.0 0.3 1.5 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 PHD PF00628.29 EAQ92375.1 - 0.00029 20.7 8.8 0.00029 20.7 8.8 3.9 2 2 0 3 3 3 1 PHD-finger Chromo PF00385.24 EAQ92375.1 - 0.0065 16.4 4.5 0.024 14.5 0.4 3.3 3 0 0 3 3 3 1 Chromo (CHRromatin Organisation MOdifier) domain RNHCP PF12647.7 EAQ92375.1 - 0.011 15.7 1.7 0.011 15.7 1.7 2.2 2 0 0 2 2 2 0 RNHCP domain PCI PF01399.27 EAQ92380.1 - 0.079 13.5 0.0 0.16 12.5 0.0 1.5 1 0 0 1 1 1 0 PCI domain Rep_fac-A_C PF08646.10 EAQ92381.1 - 5.7e-46 155.9 9.9 6.9e-45 152.4 4.4 2.4 2 0 0 2 2 2 2 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 EAQ92381.1 - 7.3e-38 128.4 0.5 4.1e-37 126.0 0.4 2.3 3 0 0 3 3 3 1 Replication protein A OB domain Rep-A_N PF04057.12 EAQ92381.1 - 3.1e-20 72.1 0.0 6.4e-20 71.1 0.0 1.6 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.25 EAQ92381.1 - 1.1e-17 63.7 1.1 4.5e-12 45.8 0.0 4.5 4 1 0 4 4 4 2 OB-fold nucleic acid binding domain DUF223 PF02721.14 EAQ92381.1 - 0.0025 18.1 0.2 0.017 15.4 0.2 2.3 2 0 0 2 2 2 1 Domain of unknown function DUF223 CDC24_OB3 PF17244.2 EAQ92381.1 - 0.0045 16.7 1.4 0.16 11.6 0.2 3.0 3 0 0 3 3 3 1 Cell division control protein 24, OB domain 3 DUF5521 PF17659.1 EAQ92381.1 - 0.033 12.0 0.0 0.053 11.4 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5521) POT1 PF02765.17 EAQ92381.1 - 0.036 13.9 1.4 1.3 8.9 0.0 3.3 3 0 0 3 3 3 0 Telomeric single stranded DNA binding POT1/CDC13 Amidohydro_2 PF04909.14 EAQ92382.1 - 1.4e-29 103.8 2.7 1.6e-29 103.6 2.7 1.0 1 0 0 1 1 1 1 Amidohydrolase Cyt-b5 PF00173.28 EAQ92385.1 - 2.3e-20 72.5 0.2 2.6e-20 72.3 0.2 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain RE_LlaJI PF09563.10 EAQ92385.1 - 0.14 11.3 0.2 0.16 11.1 0.2 1.0 1 0 0 1 1 1 0 LlaJI restriction endonuclease CDK2AP PF09806.9 EAQ92386.1 - 0.0081 16.2 0.1 0.013 15.5 0.1 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase 2-associated protein AMPK1_CBM PF16561.5 EAQ92388.1 - 1.8e-05 24.9 0.0 3.1e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase CBM_20 PF00686.19 EAQ92388.1 - 0.0091 15.9 0.1 0.018 14.9 0.1 1.4 1 0 0 1 1 1 1 Starch binding domain Phage_Coat_B PF05356.11 EAQ92389.1 - 0.0018 18.1 0.5 0.0066 16.3 0.0 2.1 3 0 0 3 3 3 1 Phage Coat protein B HD PF01966.22 EAQ92390.1 - 1.6e-06 28.4 1.0 2.8e-06 27.5 1.0 1.4 1 0 0 1 1 1 1 HD domain EMP24_GP25L PF01105.24 EAQ92394.1 - 5.7e-40 137.2 0.0 7.2e-40 136.9 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Sdh5 PF03937.16 EAQ92395.1 - 5.8e-25 87.1 0.3 1.7e-24 85.5 0.3 1.7 2 0 0 2 2 2 1 Flavinator of succinate dehydrogenase ASFV_J13L PF05568.11 EAQ92395.1 - 0.42 10.3 1.3 0.42 10.4 0.3 1.6 2 0 0 2 2 2 0 African swine fever virus J13L protein MIS13 PF08202.11 EAQ92396.1 - 1.7e-62 211.5 0.0 5.4e-62 209.8 0.0 1.7 2 0 0 2 2 2 1 Mis12-Mtw1 protein family ZapB PF06005.12 EAQ92396.1 - 0.096 13.1 0.1 21 5.7 0.0 2.5 2 0 0 2 2 2 0 Cell division protein ZapB DUF5082 PF16888.5 EAQ92396.1 - 0.2 11.9 0.7 0.41 10.9 0.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) Pox_Ag35 PF03286.14 EAQ92396.1 - 7.9 6.2 9.9 7.3 6.3 8.4 1.7 1 1 0 1 1 1 0 Pox virus Ag35 surface protein Aft1_HRR PF11787.8 EAQ92397.1 - 3.8e-25 88.9 4.5 3.8e-25 88.9 4.5 4.9 3 2 0 3 3 3 1 Aft1 HRR domain Aft1_HRA PF11786.8 EAQ92397.1 - 1.2e-24 86.4 9.4 1.2e-24 86.4 9.4 2.9 3 1 0 3 3 3 1 Aft1 HRA domain Aft1_OSA PF11785.8 EAQ92397.1 - 2e-23 82.6 15.4 3.8e-22 78.5 11.8 3.5 2 0 0 2 2 2 1 Aft1 osmotic stress response (OSM) domain bZIP_1 PF00170.21 EAQ92397.1 - 3.7e-10 39.8 5.0 3.7e-10 39.8 5.0 1.8 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 EAQ92397.1 - 0.00018 21.5 8.3 0.00018 21.5 8.3 1.9 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 EAQ92397.1 - 0.0005 20.5 2.1 0.0005 20.5 2.1 3.0 3 0 0 3 3 3 1 bZIP Maf transcription factor THOC7 PF05615.13 EAQ92397.1 - 0.0069 16.7 0.9 0.0069 16.7 0.9 1.7 2 0 0 2 2 2 1 Tho complex subunit 7 IFT20 PF14931.6 EAQ92397.1 - 7.7 6.7 9.6 1.4 9.1 4.6 2.1 2 0 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 GST_C_2 PF13410.6 EAQ92399.1 - 0.00049 20.1 1.8 0.00089 19.2 1.8 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EAQ92399.1 - 0.062 13.5 0.1 0.1 12.8 0.1 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Forkhead PF00250.18 EAQ92400.1 - 2.9e-14 53.1 0.0 5.3e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 EAQ92400.1 - 6.7e-05 23.2 0.0 0.00013 22.3 0.0 1.4 1 0 0 1 1 1 1 FHA domain KIAA1328 PF15369.6 EAQ92400.1 - 0.0016 18.4 0.0 0.0016 18.4 0.0 2.0 2 0 0 2 2 2 1 Uncharacterised protein KIAA1328 MAP17 PF15807.5 EAQ92401.1 - 0.0074 16.5 0.4 0.0074 16.5 0.4 2.2 2 0 0 2 2 2 1 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 HemY_N PF07219.13 EAQ92401.1 - 0.062 13.5 0.9 0.39 10.9 0.4 2.7 2 1 0 2 2 2 0 HemY protein N-terminus BT1 PF03092.16 EAQ92401.1 - 0.18 10.0 0.0 0.26 9.5 0.0 1.1 1 0 0 1 1 1 0 BT1 family DUF4692 PF15763.5 EAQ92401.1 - 1.3 9.5 0.0 1.3 9.5 0.0 3.4 3 0 0 3 3 3 0 Regulator of human erythroid cell expansion (RHEX) Connexin PF00029.19 EAQ92401.1 - 2.6 7.7 5.6 0.57 9.9 0.4 2.0 2 0 0 2 2 2 0 Connexin DUF2681 PF10883.8 EAQ92401.1 - 7.8 7.0 12.5 0.35 11.3 1.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) SUR7 PF06687.12 EAQ92402.1 - 8.9e-26 90.8 5.8 8.9e-26 90.8 5.8 1.4 1 1 1 2 2 2 2 SUR7/PalI family Claudin_2 PF13903.6 EAQ92402.1 - 0.0032 17.2 1.1 0.0032 17.2 1.1 2.8 1 1 2 3 3 3 1 PMP-22/EMP/MP20/Claudin tight junction Trp_oprn_chp PF09534.10 EAQ92402.1 - 0.29 10.9 6.7 0.051 13.4 3.0 1.6 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) LapA_dom PF06305.11 EAQ92402.1 - 0.74 9.7 0.1 0.74 9.7 0.1 2.7 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain Yip1 PF04893.17 EAQ92402.1 - 1.4 8.6 15.2 0.31 10.7 10.9 1.8 2 0 0 2 2 2 0 Yip1 domain Reticulon PF02453.17 EAQ92402.1 - 4.4 7.3 9.9 2.9 7.8 5.9 2.4 2 1 0 2 2 2 0 Reticulon KAR9 PF08580.10 EAQ92406.1 - 2.1 6.8 8.0 3.1 6.2 8.0 1.2 1 0 0 1 1 1 0 Yeast cortical protein KAR9 TRP PF06011.12 EAQ92408.1 - 2.1e-163 544.0 28.2 2.5e-163 543.7 28.2 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 EAQ92408.1 - 4.8e-43 146.8 0.2 7.6e-43 146.2 0.2 1.3 1 0 0 1 1 1 1 ML-like domain E1_DerP2_DerF2 PF02221.15 EAQ92408.1 - 0.0056 17.1 0.1 0.01 16.3 0.1 1.5 1 0 0 1 1 1 1 ML domain DUF3433 PF11915.8 EAQ92410.1 - 2.5e-38 130.4 10.7 2.3e-20 72.9 1.8 3.8 6 0 0 6 6 6 2 Protein of unknown function (DUF3433) Ras PF00071.22 EAQ92411.1 - 0.017 14.7 0.0 1.9 8.0 0.0 2.1 2 0 0 2 2 2 0 Ras family AAA_7 PF12775.7 EAQ92411.1 - 0.055 13.0 0.0 1.5 8.3 0.1 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_19 PF13245.6 EAQ92411.1 - 0.12 12.7 1.2 0.17 12.2 1.2 1.5 1 1 0 1 1 1 0 AAA domain SAP130_C PF16014.5 EAQ92411.1 - 1.6 7.7 11.6 2.3 7.2 11.6 1.1 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus Peptidase_M48 PF01435.18 EAQ92412.1 - 3.3e-32 111.8 0.0 5.2e-32 111.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 Glyco_hydro_16 PF00722.21 EAQ92413.1 - 3.3e-05 23.4 0.0 3.3e-05 23.4 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Mitofilin PF09731.9 EAQ92413.1 - 0.91 8.3 23.0 1.5 7.6 23.0 1.3 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF4551 PF15087.6 EAQ92413.1 - 3.4 6.4 17.5 0.53 9.0 13.6 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF4551) SKG6 PF08693.10 EAQ92414.1 - 0.0065 15.8 5.8 0.0065 15.8 5.8 1.6 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Cir_N PF10197.9 EAQ92414.1 - 0.028 14.6 1.2 0.04 14.1 1.2 1.2 1 0 0 1 1 1 0 N-terminal domain of CBF1 interacting co-repressor CIR LapA_dom PF06305.11 EAQ92414.1 - 0.029 14.2 0.2 0.064 13.1 0.2 1.5 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain bZIP_1 PF00170.21 EAQ92415.1 - 1.2e-06 28.5 4.1 1.2e-06 28.5 4.1 1.7 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 EAQ92415.1 - 0.00021 21.3 4.1 0.00021 21.3 4.1 1.6 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 EAQ92415.1 - 0.0039 17.7 4.2 0.008 16.7 4.2 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor Dishevelled PF02377.15 EAQ92415.1 - 0.075 13.5 1.8 0.18 12.2 1.8 1.6 1 0 0 1 1 1 0 Dishevelled specific domain GAS PF13851.6 EAQ92415.1 - 0.17 11.2 0.9 0.25 10.7 0.9 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding TPR_12 PF13424.6 EAQ92416.1 - 6.7e-11 42.3 3.4 1.5e-05 25.2 0.1 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 EAQ92416.1 - 4.8e-05 23.1 0.4 0.00024 21.0 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 EAQ92416.1 - 0.00024 20.9 0.2 0.00059 19.6 0.0 1.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 EAQ92416.1 - 0.0024 17.6 0.0 0.0047 16.7 0.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat PEGSRP PF07623.11 EAQ92416.1 - 0.05 13.4 0.3 0.13 12.1 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1584) TPR_8 PF13181.6 EAQ92416.1 - 0.063 13.5 0.0 0.16 12.3 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TerY_C PF15616.6 EAQ92416.1 - 0.13 12.3 0.0 0.17 12.0 0.0 1.1 1 0 0 1 1 1 0 TerY-C metal binding domain zf-C2H2 PF00096.26 EAQ92418.1 - 1e-06 28.9 32.2 3.3e-06 27.2 2.1 5.4 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EAQ92418.1 - 0.00015 22.3 0.9 0.00015 22.3 0.9 6.6 7 0 0 7 7 7 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 EAQ92418.1 - 0.001 19.0 0.7 0.0042 17.1 0.7 2.1 1 0 0 1 1 1 1 C2H2-type zinc finger zf-met PF12874.7 EAQ92418.1 - 0.017 15.5 18.1 0.093 13.2 0.1 5.1 5 0 0 5 5 5 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EAQ92418.1 - 0.034 14.4 19.8 0.048 14.0 0.3 5.1 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 EAQ92418.1 - 0.28 11.7 13.6 1 9.9 5.1 3.7 3 0 0 3 3 3 0 Zinc-finger double domain AT_hook PF02178.19 EAQ92419.1 - 0.00082 19.0 17.1 0.038 13.8 5.2 2.9 2 0 0 2 2 2 2 AT hook motif MULE PF10551.9 EAQ92420.1 - 9.6e-30 102.9 0.1 1.9e-29 102.0 0.1 1.5 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.18 EAQ92420.1 - 7.4e-06 25.1 0.0 9.5e-06 24.7 0.0 1.1 1 0 0 1 1 1 1 Transposase, Mutator family DUF1360 PF07098.11 EAQ92420.1 - 0.053 13.5 0.0 0.088 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1360) Bradykinin PF06753.12 EAQ92421.1 - 3.5 7.4 7.8 0.53 10.0 1.8 2.7 2 0 0 2 2 2 0 Bradykinin PPR_2 PF13041.6 EAQ92423.1 - 5.3e-14 52.2 0.0 1.6e-13 50.6 0.0 1.9 1 0 0 1 1 1 1 PPR repeat family PPR_1 PF12854.7 EAQ92423.1 - 1.5e-10 40.5 0.0 2.4e-08 33.5 0.0 2.7 2 0 0 2 2 2 2 PPR repeat PPR_3 PF13812.6 EAQ92423.1 - 5.6e-08 32.7 0.0 1.4e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 Pentatricopeptide repeat domain PPR PF01535.20 EAQ92423.1 - 5.3e-07 29.5 0.5 1.1e-05 25.3 0.0 3.2 4 0 0 4 4 4 1 PPR repeat PPR_long PF17177.4 EAQ92423.1 - 6.9e-05 22.3 0.0 0.00012 21.5 0.0 1.3 1 0 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP cwf18 PF08315.12 EAQ92424.1 - 6.8e-43 146.6 6.6 6.8e-43 146.6 6.6 1.7 2 0 0 2 2 2 1 cwf18 pre-mRNA splicing factor Endonuc_Holl PF10107.9 EAQ92424.1 - 0.15 11.9 0.4 0.35 10.7 0.4 1.5 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase MitMem_reg PF13012.6 EAQ92427.1 - 2.1e-18 66.8 0.7 4e-18 65.9 0.2 1.7 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function JAB PF01398.21 EAQ92427.1 - 1.2e-17 63.9 0.0 2.1e-17 63.2 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease UPF0172 PF03665.13 EAQ92427.1 - 0.18 11.8 0.0 0.83 9.7 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0172) UTP25 PF06862.12 EAQ92428.1 - 6.3e-189 628.7 0.7 1.2e-188 627.7 0.7 1.4 1 1 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 DEAD PF00270.29 EAQ92428.1 - 0.00057 19.7 0.0 0.021 14.6 0.0 2.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase Ribosomal_L17 PF01196.19 EAQ92429.1 - 1.9e-32 112.0 0.1 2.9e-32 111.4 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L17 Mrpl_C PF18502.1 EAQ92429.1 - 0.036 14.3 0.0 0.8 10.0 0.0 2.2 2 0 0 2 2 2 0 54S ribosomal protein L8 C-terminal domain AIM5 PF17050.5 EAQ92430.1 - 1.7e-20 73.6 0.7 1.7e-20 73.6 0.7 2.6 3 0 0 3 3 3 1 Altered inheritance of mitochondria 5 PqqD PF05402.12 EAQ92430.1 - 0.083 13.2 0.5 0.16 12.3 0.5 1.5 1 0 0 1 1 1 0 Coenzyme PQQ synthesis protein D (PqqD) Acyl_transf_3 PF01757.22 EAQ92431.1 - 1.7e-72 244.3 20.4 2.1e-72 244.0 20.4 1.1 1 0 0 1 1 1 1 Acyltransferase family ALAD PF00490.21 EAQ92432.1 - 6.4e-120 400.1 0.0 7.4e-120 399.9 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase NDC10_II PF16787.5 EAQ92433.1 - 1.4e-59 201.7 0.0 2.3e-59 201.0 0.0 1.3 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 DDE_1 PF03184.19 EAQ92433.1 - 3.8e-28 98.3 0.0 6.7e-28 97.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease GCR1_C PF12550.8 EAQ92433.1 - 4.7e-19 68.5 1.1 1e-18 67.4 0.3 2.1 2 0 0 2 2 2 1 Transcriptional activator of glycolytic enzymes HTH_psq PF05225.16 EAQ92433.1 - 8.9e-10 38.2 0.2 2.1e-09 37.0 0.2 1.7 1 0 0 1 1 1 1 helix-turn-helix, Psq domain ZapB PF06005.12 EAQ92433.1 - 1.5 9.3 7.7 0.21 12.1 0.7 3.2 4 0 0 4 4 4 0 Cell division protein ZapB Y_phosphatase3 PF13350.6 EAQ92436.1 - 1.5e-25 90.5 0.0 1.7e-25 90.4 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Toxin_36 PF10550.9 EAQ92436.1 - 0.13 13.7 0.1 0.46 12.0 0.1 2.0 1 0 0 1 1 1 0 Conantokin-G mollusc-toxin S4 PF01479.25 EAQ92438.1 - 4.1e-11 42.4 0.2 1.3e-10 40.8 0.1 1.9 2 0 0 2 2 2 1 S4 domain Ribosomal_S4 PF00163.19 EAQ92438.1 - 1.3e-10 42.0 1.2 2.1e-10 41.4 1.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain THDPS_N_2 PF14805.6 EAQ92438.1 - 0.12 12.7 0.1 0.2 11.9 0.1 1.4 1 0 0 1 1 1 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal Ribosomal_S18 PF01084.20 EAQ92439.1 - 1.5e-13 50.7 0.0 3.6e-13 49.5 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S18 PPR PF01535.20 EAQ92440.1 - 6e-07 29.3 0.0 0.092 13.0 0.0 4.9 4 0 0 4 4 4 2 PPR repeat PPR_2 PF13041.6 EAQ92440.1 - 0.00082 19.5 0.0 2.4 8.4 0.0 4.4 5 0 0 5 5 5 2 PPR repeat family TPR_15 PF13429.6 EAQ92440.1 - 0.0054 16.0 0.1 0.34 10.1 0.1 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat FTA4 PF13093.6 EAQ92441.1 - 1.6e-71 240.4 0.0 2e-71 240.0 0.0 1.1 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Alkyl_sulf_dimr PF14863.6 EAQ92441.1 - 0.11 12.9 2.7 4.6 7.7 0.0 2.2 2 0 0 2 2 2 0 Alkyl sulfatase dimerisation ArfGap PF01412.18 EAQ92442.1 - 1.6e-36 124.9 0.0 3.7e-36 123.7 0.0 1.6 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Methyltransf_23 PF13489.6 EAQ92443.1 - 8.4e-18 64.7 0.0 1.2e-17 64.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAQ92443.1 - 7.7e-08 32.9 0.0 2.3e-07 31.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EAQ92443.1 - 2.9e-05 24.7 0.0 0.00019 22.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAQ92443.1 - 3.2e-05 23.8 0.0 0.0011 18.8 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EAQ92443.1 - 0.0014 19.2 0.0 0.0029 18.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EAQ92443.1 - 0.018 14.6 0.0 0.12 12.0 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase small domain Ubie_methyltran PF01209.18 EAQ92443.1 - 0.052 12.9 0.0 0.3 10.4 0.0 2.2 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 EAQ92443.1 - 0.13 11.7 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_16 PF10294.9 EAQ92443.1 - 0.16 11.7 0.0 0.24 11.1 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase Pyridoxal_deC PF00282.19 EAQ92444.1 - 2.2e-05 23.3 0.0 0.00023 20.0 0.0 2.0 2 0 0 2 2 2 1 Pyridoxal-dependent decarboxylase conserved domain B5 PF03484.15 EAQ92444.1 - 0.12 12.7 0.0 0.22 11.8 0.0 1.7 1 1 0 1 1 1 0 tRNA synthetase B5 domain ATG7_N PF16420.5 EAQ92445.1 - 2.3e-55 188.4 0.0 3.2e-37 128.8 0.0 2.3 1 1 1 2 2 2 2 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus ThiF PF00899.21 EAQ92445.1 - 7.6e-45 153.2 0.0 1.2e-44 152.5 0.0 1.3 1 0 0 1 1 1 1 ThiF family DUF2462 PF09495.10 EAQ92445.1 - 5.6e-11 43.0 6.0 1.2e-10 41.9 6.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2462) Shikimate_DH PF01488.20 EAQ92445.1 - 0.16 12.0 0.0 0.79 9.8 0.0 1.9 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase dCMP_cyt_deam_1 PF00383.23 EAQ92446.1 - 2.7e-27 94.6 0.9 4.1e-27 94.0 0.9 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EAQ92446.1 - 5.4e-13 48.9 0.1 9.2e-13 48.1 0.1 1.3 1 0 0 1 1 1 1 MafB19-like deaminase TSA PF03249.13 EAQ92446.1 - 0.11 11.3 0.1 0.17 10.7 0.1 1.2 1 0 0 1 1 1 0 Type specific antigen AAA_18 PF13238.6 EAQ92446.1 - 0.17 12.4 0.0 0.61 10.6 0.0 1.8 1 1 0 1 1 1 0 AAA domain Glyco_hydro_61 PF03443.14 EAQ92448.1 - 5.2e-59 199.6 0.1 6.2e-59 199.4 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Bile_Hydr_Trans PF04775.14 EAQ92448.1 - 0.2 11.7 0.1 0.36 10.9 0.1 1.4 1 0 0 1 1 1 0 Acyl-CoA thioester hydrolase/BAAT N-terminal region 2Fe-2S_thioredx PF01257.19 EAQ92449.1 - 3.9e-59 198.7 0.1 4.9e-59 198.4 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin HSP9_HSP12 PF04119.12 EAQ92449.1 - 0.096 13.1 0.0 0.22 11.9 0.0 1.5 1 0 0 1 1 1 0 Heat shock protein 9/12 Kelch_3 PF13415.6 EAQ92450.1 - 1.4e-18 66.7 17.3 0.00025 21.2 0.1 7.8 8 0 0 8 8 8 5 Galactose oxidase, central domain Kelch_6 PF13964.6 EAQ92450.1 - 1.1e-17 63.6 0.5 2.7e-05 24.3 0.0 5.8 6 0 0 6 6 5 3 Kelch motif Kelch_4 PF13418.6 EAQ92450.1 - 2.6e-16 59.3 19.1 0.00069 19.6 0.1 7.3 7 1 1 8 8 8 4 Galactose oxidase, central domain Kelch_1 PF01344.25 EAQ92450.1 - 3.1e-15 55.5 6.6 1.3e-06 27.9 0.0 6.0 6 0 0 6 6 6 3 Kelch motif Kelch_5 PF13854.6 EAQ92450.1 - 2.1e-14 53.1 7.1 3.9e-05 23.5 0.0 6.7 7 0 0 7 7 7 2 Kelch motif Kelch_2 PF07646.15 EAQ92450.1 - 2.8e-10 39.7 6.6 1.8e-05 24.5 0.2 5.5 5 1 0 5 5 5 1 Kelch motif Sporozoite_P67 PF05642.11 EAQ92450.1 - 0.02 13.0 3.5 0.03 12.4 3.5 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SDA1 PF05285.12 EAQ92450.1 - 0.034 13.6 8.7 0.052 13.0 8.7 1.2 1 0 0 1 1 1 0 SDA1 Sigma70_ner PF04546.13 EAQ92450.1 - 0.053 13.4 6.9 0.088 12.7 6.9 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region FYDLN_acid PF09538.10 EAQ92450.1 - 0.077 13.7 12.0 0.18 12.5 12.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Nop14 PF04147.12 EAQ92450.1 - 0.11 10.7 12.9 0.14 10.3 12.9 1.0 1 0 0 1 1 1 0 Nop14-like family DUF2457 PF10446.9 EAQ92450.1 - 0.17 11.0 18.9 0.27 10.3 18.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NOA36 PF06524.12 EAQ92450.1 - 0.21 10.9 15.5 0.33 10.2 15.5 1.2 1 0 0 1 1 1 0 NOA36 protein BSP_II PF05432.11 EAQ92450.1 - 0.23 11.1 10.5 0.35 10.5 10.5 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) RXT2_N PF08595.11 EAQ92450.1 - 0.4 10.7 7.9 0.67 10.0 7.9 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal PPP4R2 PF09184.11 EAQ92450.1 - 0.57 9.7 11.9 0.83 9.2 11.9 1.2 1 0 0 1 1 1 0 PPP4R2 FAM176 PF14851.6 EAQ92450.1 - 0.76 9.4 7.8 1.5 8.5 7.8 1.4 1 0 0 1 1 1 0 FAM176 family Pox_Ag35 PF03286.14 EAQ92450.1 - 1 9.1 9.2 1.7 8.4 9.2 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CDC45 PF02724.14 EAQ92450.1 - 1.3 7.3 11.1 1.8 6.7 11.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Cwf_Cwc_15 PF04889.12 EAQ92450.1 - 1.4 8.6 16.4 2.2 7.9 16.4 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein BUD22 PF09073.10 EAQ92450.1 - 1.7 7.9 14.4 2.6 7.3 14.4 1.2 1 0 0 1 1 1 0 BUD22 DUF2722 PF10846.8 EAQ92450.1 - 1.8 7.5 7.3 2.5 6.9 7.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) TFB6 PF17110.5 EAQ92450.1 - 2 8.1 6.8 3.2 7.5 6.8 1.2 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH TLP-20 PF06088.11 EAQ92450.1 - 3.5 7.5 8.0 5.5 6.8 8.0 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) CobT PF06213.12 EAQ92450.1 - 6.8 6.0 13.6 12 5.2 13.6 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Ceramidase_alk PF04734.13 EAQ92451.1 - 7.7e-220 730.8 0.0 8.9e-220 730.6 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 EAQ92451.1 - 5.5e-55 185.8 0.0 9.3e-55 185.0 0.0 1.4 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal BCAS2 PF05700.11 EAQ92452.1 - 2.5e-45 154.7 6.7 1.3e-44 152.4 6.7 1.8 1 1 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) DUF4510 PF14971.6 EAQ92452.1 - 0.044 14.1 2.8 0.044 14.1 2.8 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4510) TMF_TATA_bd PF12325.8 EAQ92452.1 - 0.075 13.3 0.1 0.12 12.6 0.1 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding cNMP_binding PF00027.29 EAQ92453.1 - 1.7e-24 85.7 0.0 2.8e-21 75.4 0.0 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain CDC50 PF03381.15 EAQ92454.1 - 3.9e-85 285.8 0.5 4.8e-85 285.5 0.5 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family FACT-Spt16_Nlob PF14826.6 EAQ92455.1 - 4.7e-58 195.5 0.6 1.4e-57 194.0 0.6 1.9 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain SPT16 PF08644.11 EAQ92455.1 - 1.6e-54 184.2 0.2 1.6e-54 184.2 0.2 2.7 3 0 0 3 3 3 1 FACT complex subunit (SPT16/CDC68) Peptidase_M24 PF00557.24 EAQ92455.1 - 5.1e-28 98.2 0.0 1e-27 97.2 0.0 1.5 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 EAQ92455.1 - 3.2e-15 56.3 0.2 1.1e-14 54.5 0.0 2.1 2 0 0 2 2 2 1 Histone chaperone Rttp106-like GCS PF03074.16 EAQ92460.1 - 3e-174 579.6 0.0 3.8e-174 579.3 0.0 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase Glycophorin_A PF01102.18 EAQ92461.1 - 0.00033 20.9 0.1 0.0013 19.0 0.1 2.0 1 0 0 1 1 1 1 Glycophorin A CFEM PF05730.11 EAQ92461.1 - 0.0077 16.3 1.6 0.015 15.4 1.6 1.4 1 0 0 1 1 1 1 CFEM domain DEAD PF00270.29 EAQ92462.1 - 6e-36 123.9 0.3 1.5e-35 122.6 0.2 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EAQ92462.1 - 9.7e-25 87.1 0.0 3.5e-24 85.3 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EAQ92462.1 - 6.9e-05 22.9 0.0 0.00011 22.3 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 EAQ92462.1 - 0.0002 21.1 0.0 0.00041 20.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain CMS1 PF14617.6 EAQ92462.1 - 0.0034 16.8 0.0 0.0063 15.9 0.0 1.3 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit AAA_19 PF13245.6 EAQ92462.1 - 0.035 14.4 0.0 0.47 10.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain FCH PF00611.23 EAQ92463.1 - 8.8e-19 67.6 1.3 2.3e-18 66.2 0.3 2.4 2 1 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.6 EAQ92463.1 - 5e-16 58.3 0.1 7.9e-14 51.2 0.0 2.6 2 0 0 2 2 2 1 Variant SH3 domain C1_1 PF00130.22 EAQ92463.1 - 2.5e-15 56.1 5.6 3.9e-15 55.5 5.6 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_1 PF00018.28 EAQ92463.1 - 6.5e-05 22.5 0.1 0.00027 20.5 0.0 1.9 2 0 0 2 2 2 1 SH3 domain C1_2 PF03107.16 EAQ92463.1 - 0.01 16.1 5.0 0.018 15.4 5.0 1.3 1 0 0 1 1 1 0 C1 domain SH3_10 PF17902.1 EAQ92463.1 - 0.066 13.3 0.0 0.23 11.5 0.0 1.9 1 0 0 1 1 1 0 SH3 domain Allexi_40kDa PF05549.11 EAQ92463.1 - 0.085 12.4 0.4 0.97 8.9 0.0 2.2 2 0 0 2 2 2 0 Allexivirus 40kDa protein FYVE PF01363.21 EAQ92463.1 - 0.36 11.0 4.1 0.77 9.9 4.1 1.5 1 0 0 1 1 1 0 FYVE zinc finger Glyco_hydro_72 PF03198.14 EAQ92464.1 - 1e-115 386.3 4.2 1.4e-115 385.9 4.2 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 EAQ92464.1 - 2e-08 34.0 2.9 2.9e-07 30.2 2.9 2.2 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF2713 PF10897.8 EAQ92464.1 - 0.029 14.0 0.1 0.052 13.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2713) SUIM_assoc PF16619.5 EAQ92466.1 - 0.12 12.4 9.6 0.26 11.4 9.6 1.5 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 PRIMA1 PF16101.5 EAQ92466.1 - 0.39 10.8 7.2 1.3 9.1 7.2 1.8 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 CAP_N PF01213.19 EAQ92466.1 - 2.7 7.4 6.0 4.1 6.8 6.0 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Coatomer_E PF04733.14 EAQ92467.1 - 5e-61 206.6 7.5 5.7e-61 206.5 7.5 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit ANAPC3 PF12895.7 EAQ92467.1 - 1.2e-06 28.7 2.4 0.33 11.2 0.4 3.6 3 1 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 EAQ92467.1 - 2.5e-06 27.9 29.0 0.00012 22.5 1.4 4.6 3 1 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 EAQ92467.1 - 9.1e-05 22.1 1.1 0.23 11.3 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_15 PF13429.6 EAQ92467.1 - 0.00014 21.2 12.2 0.00045 19.5 1.9 2.3 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 EAQ92467.1 - 0.00043 20.7 9.4 0.67 10.7 0.0 5.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 EAQ92467.1 - 0.00048 20.1 3.2 1.3 9.5 0.0 5.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.6 EAQ92467.1 - 0.0061 17.3 1.2 0.0061 17.3 1.2 6.5 4 3 2 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 EAQ92467.1 - 0.01 16.1 16.4 0.067 13.5 1.2 4.8 3 3 1 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 EAQ92467.1 - 0.021 14.9 0.0 0.021 14.9 0.0 6.7 8 0 0 8 8 8 0 Tetratricopeptide repeat Smr PF01713.21 EAQ92467.1 - 0.04 14.3 0.0 0.12 12.7 0.0 1.8 1 0 0 1 1 1 0 Smr domain TPR_4 PF07721.14 EAQ92467.1 - 0.059 14.0 1.5 0.059 14.0 1.5 6.2 7 0 0 7 7 5 0 Tetratricopeptide repeat Type_III_YscG PF09477.10 EAQ92467.1 - 0.28 11.3 9.4 0.14 12.3 1.0 3.6 1 1 4 5 5 5 0 Bacterial type II secretion system chaperone protein (type_III_yscG) AAA_lid_2 PF17863.1 EAQ92467.1 - 0.4 10.6 9.0 5.2 7.0 0.4 2.6 2 0 0 2 2 2 0 AAA lid domain TPR_7 PF13176.6 EAQ92467.1 - 2 8.6 14.1 3.4 7.9 0.1 6.0 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_16 PF13432.6 EAQ92467.1 - 2.6 8.8 36.2 0.18 12.5 2.8 5.7 2 2 4 6 6 6 0 Tetratricopeptide repeat PS_Dcarbxylase PF02666.15 EAQ92468.1 - 5e-54 182.9 0.0 7.8e-54 182.3 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.30 EAQ92468.1 - 6.8e-31 106.6 0.0 2.6e-17 63.0 0.0 2.5 2 0 0 2 2 2 2 C2 domain EF-hand_1 PF00036.32 EAQ92468.1 - 0.0037 16.7 0.0 0.018 14.5 0.0 2.3 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.6 EAQ92468.1 - 0.033 13.7 0.2 0.22 11.1 0.0 2.5 2 0 0 2 2 2 0 EF hand EF-hand_7 PF13499.6 EAQ92468.1 - 0.053 14.0 0.1 0.18 12.3 0.1 1.9 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_6 PF13405.6 EAQ92468.1 - 0.054 13.4 0.0 0.29 11.2 0.0 2.3 1 0 0 1 1 1 0 EF-hand domain DAO PF01266.24 EAQ92469.1 - 1.8e-09 37.7 0.1 8.1e-08 32.2 0.0 2.1 1 1 0 2 2 2 2 FAD dependent oxidoreductase K_oxygenase PF13434.6 EAQ92469.1 - 0.053 12.7 0.1 0.073 12.2 0.1 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 EAQ92469.1 - 0.091 12.7 0.1 5.2 7.0 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding DUF3405 PF11885.8 EAQ92470.1 - 8.7e-180 598.7 2.4 8.7e-180 598.7 2.4 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3405) LIM PF00412.22 EAQ92472.1 - 2.5e-21 75.7 9.8 1.2e-11 44.6 2.2 2.2 2 0 0 2 2 2 2 LIM domain zf-C2H2 PF00096.26 EAQ92472.1 - 0.58 10.7 4.6 9.8 6.9 1.6 3.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf_C2H2_13 PF18508.1 EAQ92472.1 - 2.4 7.8 4.1 39 4.0 0.7 3.3 3 0 0 3 3 3 0 Zinc finger domain TNFR_c6 PF00020.18 EAQ92472.1 - 4 7.9 9.8 2.9 8.4 0.1 3.0 3 0 0 3 3 3 0 TNFR/NGFR cysteine-rich region Inos-1-P_synth PF01658.17 EAQ92473.1 - 3e-45 152.9 0.7 4.6e-45 152.4 0.7 1.3 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase NAD_binding_5 PF07994.12 EAQ92473.1 - 1.3e-32 113.5 0.0 4.7e-29 101.8 0.0 2.0 1 1 1 2 2 2 2 Myo-inositol-1-phosphate synthase AMP-binding PF00501.28 EAQ92474.1 - 1.2e-85 287.7 0.0 1.5e-85 287.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EAQ92474.1 - 1.1e-14 55.2 0.8 3.4e-14 53.6 0.8 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain MFS_1 PF07690.16 EAQ92476.1 - 6.1e-20 71.4 53.6 7.2e-13 48.2 19.3 2.7 1 1 2 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.24 EAQ92476.1 - 6.2e-13 48.4 28.9 5.1e-06 25.6 3.5 3.2 2 1 1 3 3 3 3 Sugar (and other) transporter DnaJ PF00226.31 EAQ92477.1 - 2.7e-11 43.4 0.0 4.5e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain NIL PF09383.10 EAQ92477.1 - 0.02 14.7 0.0 0.052 13.4 0.0 1.6 2 0 0 2 2 2 0 NIL domain Pro_Al_protease PF02983.14 EAQ92477.1 - 0.21 11.7 0.9 11 6.1 0.0 2.7 1 1 1 2 2 2 0 Alpha-lytic protease prodomain Pectate_lyase_3 PF12708.7 EAQ92478.1 - 4.2e-22 79.0 2.2 1.1e-21 77.6 1.1 2.2 2 0 0 2 2 2 1 Pectate lyase superfamily protein Beta_helix PF13229.6 EAQ92478.1 - 5.6e-07 29.5 4.9 1.9e-06 27.8 5.0 1.9 2 0 0 2 2 2 1 Right handed beta helix region NosD PF05048.13 EAQ92478.1 - 7.4e-06 25.4 0.8 7.4e-06 25.4 0.8 1.8 2 1 0 2 2 2 1 Periplasmic copper-binding protein (NosD) Adeno_E1B_55K PF01696.17 EAQ92478.1 - 9.8e-05 21.2 0.9 0.00014 20.7 0.9 1.2 1 0 0 1 1 1 1 Adenovirus EB1 55K protein / large t-antigen SCP2 PF02036.17 EAQ92479.1 - 1.9e-24 86.1 0.3 2.2e-24 85.9 0.3 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 EAQ92479.1 - 2.5e-07 31.0 0.1 3.1e-07 30.7 0.1 1.2 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal SCP2_2 PF13530.6 EAQ92479.1 - 0.00042 20.7 0.1 0.00052 20.4 0.1 1.2 1 0 0 1 1 1 1 Sterol carrier protein domain YebF PF13995.6 EAQ92479.1 - 0.1 12.6 0.0 0.15 12.1 0.0 1.2 1 0 0 1 1 1 0 YebF-like protein Nucleoporin_FG PF13634.6 EAQ92480.1 - 1.7e-11 44.8 66.0 4.1e-08 33.9 14.5 10.1 1 1 6 9 9 9 6 Nucleoporin FG repeat region Ran_BP1 PF00638.18 EAQ92480.1 - 2.8e-11 43.8 0.0 1.3e-10 41.5 0.0 2.0 1 1 0 1 1 1 1 RanBP1 domain DUF808 PF05661.12 EAQ92481.1 - 0.11 11.6 0.4 0.15 11.1 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF808) Tfb5 PF06331.12 EAQ92482.1 - 6.6e-19 67.7 1.8 8.8e-19 67.3 1.8 1.2 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 CmcI PF04989.12 EAQ92482.1 - 0.062 13.0 0.6 0.068 12.8 0.6 1.1 1 0 0 1 1 1 0 Cephalosporin hydroxylase ECH_1 PF00378.20 EAQ92483.1 - 8.7e-41 139.9 0.5 3e-40 138.1 0.5 1.7 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EAQ92483.1 - 3.4e-34 118.8 0.2 1.6e-31 110.1 0.1 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase PEP_hydrolase PF09370.10 EAQ92483.1 - 0.005 16.1 0.1 0.0098 15.1 0.1 1.4 1 0 0 1 1 1 1 Phosphoenolpyruvate hydrolase-like SAM_2 PF07647.17 EAQ92484.1 - 2.6e-13 49.9 0.0 4.6e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_1 PF00018.28 EAQ92484.1 - 1.7e-12 46.7 0.0 3.2e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EAQ92484.1 - 5.7e-12 45.3 0.0 1.2e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain PH PF00169.29 EAQ92484.1 - 1.5e-07 31.9 0.0 7.4e-07 29.6 0.0 2.1 1 1 0 1 1 1 1 PH domain SH3_2 PF07653.17 EAQ92484.1 - 4e-05 23.2 0.0 8.8e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain PH_11 PF15413.6 EAQ92484.1 - 0.026 14.9 0.1 0.07 13.6 0.1 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain PH_8 PF15409.6 EAQ92484.1 - 0.07 13.4 0.0 0.42 10.9 0.0 2.2 2 0 0 2 2 2 0 Pleckstrin homology domain Nucleopor_Nup85 PF07575.13 EAQ92485.1 - 1.1e-15 57.2 0.0 4.4e-08 32.2 0.0 2.6 2 1 0 2 2 2 2 Nup85 Nucleoporin DUF952 PF06108.12 EAQ92486.1 - 3.3e-15 55.8 0.0 2.2e-14 53.2 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF952) ADH_N PF08240.12 EAQ92487.1 - 3.5e-27 94.4 1.4 8e-27 93.3 1.4 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EAQ92487.1 - 1.4e-20 73.5 0.2 2.6e-20 72.7 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EAQ92487.1 - 0.0027 17.0 0.5 0.0047 16.2 0.5 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 EAQ92487.1 - 0.011 15.4 0.1 0.019 14.6 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Sacchrp_dh_NADP PF03435.18 EAQ92487.1 - 0.056 13.7 0.1 0.11 12.8 0.1 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain ADH_zinc_N_2 PF13602.6 EAQ92487.1 - 0.061 14.4 0.0 0.16 13.0 0.0 1.7 1 1 0 1 1 1 0 Zinc-binding dehydrogenase TrkA_N PF02254.18 EAQ92487.1 - 0.11 12.7 1.1 0.14 12.4 0.0 1.7 2 0 0 2 2 2 0 TrkA-N domain zf-AN1 PF01428.16 EAQ92489.1 - 2.4e-13 50.0 5.2 2.4e-13 50.0 5.2 1.5 1 1 0 1 1 1 1 AN1-like Zinc finger C5HCH PF17982.1 EAQ92489.1 - 0.0066 16.6 6.3 0.02 15.1 6.3 1.8 1 1 1 2 2 2 1 NSD Cys-His rich domain DUF682 PF05081.12 EAQ92489.1 - 0.019 14.7 0.2 0.021 14.6 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF682) Transp_Tc5_C PF04236.15 EAQ92489.1 - 0.045 14.1 7.0 0.045 14.1 7.0 1.7 1 1 1 2 2 2 0 Tc5 transposase C-terminal domain DUF676 PF05057.14 EAQ92490.1 - 4.3e-53 180.1 0.0 7.8e-53 179.2 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) HHH PF00633.23 EAQ92490.1 - 1.4e-06 27.9 0.0 3.5e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif HhH-GPD PF00730.25 EAQ92490.1 - 0.0001 22.7 0.0 0.0056 17.1 0.0 2.5 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein Abhydrolase_6 PF12697.7 EAQ92490.1 - 0.00034 21.3 0.0 0.00034 21.3 0.0 2.5 2 2 0 2 2 2 1 Alpha/beta hydrolase family Palm_thioest PF02089.15 EAQ92490.1 - 0.00045 20.1 0.0 0.00077 19.4 0.0 1.3 1 0 0 1 1 1 1 Palmitoyl protein thioesterase PGAP1 PF07819.13 EAQ92490.1 - 0.0043 16.8 0.2 0.038 13.7 0.2 2.1 1 1 0 1 1 1 1 PGAP1-like protein Lipase_2 PF01674.18 EAQ92490.1 - 0.0049 16.4 0.0 0.0098 15.4 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 2) FAD_binding_6 PF00970.24 EAQ92490.1 - 0.16 12.4 0.0 0.32 11.4 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain DUF2793 PF10983.8 EAQ92491.1 - 0.12 12.2 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2793) GDPD PF03009.17 EAQ92492.1 - 1.9e-31 109.7 0.0 1.5e-30 106.8 0.0 1.9 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.6 EAQ92492.1 - 0.0026 18.1 0.4 0.0068 16.8 0.4 1.8 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Fungal_trans PF04082.18 EAQ92493.1 - 1.3e-30 106.3 0.0 2.3e-30 105.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EAQ92493.1 - 2.6e-10 40.2 11.1 5e-10 39.3 11.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fez1 PF06818.15 EAQ92493.1 - 0.027 14.9 0.4 0.057 13.9 0.4 1.5 1 0 0 1 1 1 0 Fez1 bZIP_1 PF00170.21 EAQ92493.1 - 0.098 12.8 0.3 0.27 11.3 0.3 1.8 1 0 0 1 1 1 0 bZIP transcription factor SET PF00856.28 EAQ92494.1 - 1.4e-05 25.6 0.0 2.6e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 SET domain MMR_HSR1_C PF08438.10 EAQ92495.1 - 1.8e-37 128.3 0.0 3.2e-37 127.5 0.0 1.4 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.23 EAQ92495.1 - 2.6e-16 59.7 0.0 6.2e-16 58.5 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EAQ92495.1 - 1.2e-05 24.9 0.1 0.00042 19.9 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EAQ92495.1 - 0.00067 19.6 0.5 0.063 13.2 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase ABC_tran PF00005.27 EAQ92495.1 - 0.028 14.9 0.0 0.36 11.3 0.0 2.2 2 0 0 2 2 2 0 ABC transporter Dynamin_N PF00350.23 EAQ92495.1 - 0.038 14.0 2.1 0.16 12.0 0.5 2.5 3 0 0 3 3 3 0 Dynamin family MMR_HSR1_Xtn PF16897.5 EAQ92495.1 - 0.039 14.0 0.1 0.087 12.8 0.1 1.5 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain GTP_EFTU PF00009.27 EAQ92495.1 - 0.045 13.3 0.5 0.79 9.2 0.0 2.5 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain AIG1 PF04548.16 EAQ92495.1 - 0.15 11.4 0.0 0.37 10.1 0.0 1.8 2 0 0 2 2 2 0 AIG1 family CTU2 PF10288.9 EAQ92495.1 - 0.22 11.8 0.0 0.37 11.0 0.0 1.4 1 0 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 tRNA-synt_2b PF00587.25 EAQ92496.1 - 6e-32 111.1 0.0 1.1e-31 110.2 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EAQ92496.1 - 3.1e-07 30.5 0.0 6.2e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain CBF PF03914.17 EAQ92497.1 - 5.9e-57 192.4 4.6 8.4e-57 191.9 0.1 2.9 3 0 0 3 3 3 1 CBF/Mak21 family Mo25 PF08569.11 EAQ92497.1 - 0.0075 15.7 0.1 0.018 14.4 0.1 1.6 1 0 0 1 1 1 1 Mo25-like DUF4481 PF14800.6 EAQ92497.1 - 0.053 13.0 0.1 0.11 11.9 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4481) 4HBT PF03061.22 EAQ92498.1 - 3.1e-09 37.0 0.0 5.1e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily V-ATPase_C PF03223.15 EAQ92499.1 - 9.4e-75 252.3 0.2 1.1e-74 252.1 0.2 1.0 1 0 0 1 1 1 1 V-ATPase subunit C AT_hook PF02178.19 EAQ92500.1 - 2.9 8.1 17.8 9.6 6.5 5.7 3.1 2 0 0 2 2 2 0 AT hook motif F-box PF00646.33 EAQ92501.1 - 3.9e-06 26.6 0.5 8.4e-06 25.5 0.5 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EAQ92501.1 - 0.0022 17.8 0.2 0.0066 16.3 0.2 1.8 1 0 0 1 1 1 1 F-box-like SH3_9 PF14604.6 EAQ92503.1 - 1.7e-28 98.2 4.1 1.3e-13 50.6 0.4 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 EAQ92503.1 - 2.9e-25 87.6 4.6 7.4e-12 44.7 0.6 2.4 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 EAQ92503.1 - 6.9e-16 57.7 0.0 3.5e-07 29.8 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain Cofilin_ADF PF00241.20 EAQ92503.1 - 4.9e-15 55.4 0.0 1e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Glutaredoxin PF00462.24 EAQ92505.1 - 6.9e-18 64.6 0.0 3.4e-17 62.4 0.0 2.2 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.20 EAQ92505.1 - 5.3e-14 52.1 0.0 1.4e-13 50.7 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 EAQ92505.1 - 0.0081 16.5 0.0 4.4 7.7 0.0 2.6 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.6 EAQ92505.1 - 0.052 14.0 0.0 1.9 8.9 0.0 3.1 1 1 2 3 3 3 0 Thioredoxin-like domain HyaE PF07449.11 EAQ92505.1 - 0.099 12.6 0.0 0.41 10.6 0.0 1.9 3 0 0 3 3 3 0 Hydrogenase-1 expression protein HyaE RdRP PF05183.12 EAQ92505.1 - 0.23 10.1 0.0 0.3 9.7 0.0 1.1 1 0 0 1 1 1 0 RNA dependent RNA polymerase Fungal_trans PF04082.18 EAQ92506.1 - 3.1e-18 65.8 0.2 5e-18 65.1 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Alpha-amylase PF00128.24 EAQ92507.1 - 3.3e-40 138.7 0.2 5.9e-26 91.8 0.0 3.1 1 1 0 3 3 3 3 Alpha amylase, catalytic domain DUF1966 PF09260.11 EAQ92507.1 - 5.6e-28 97.1 0.1 1e-27 96.2 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) GHL15 PF14885.6 EAQ92507.1 - 0.55 10.1 2.4 0.35 10.8 0.3 1.6 2 0 0 2 2 2 0 Hypothetical glycosyl hydrolase family 15 Fe-ADH PF00465.19 EAQ92508.1 - 0.021 13.6 0.1 0.043 12.6 0.1 1.4 2 0 0 2 2 2 0 Iron-containing alcohol dehydrogenase K_channel_TID PF07941.11 EAQ92508.1 - 0.64 10.5 11.8 1.4 9.4 11.1 2.0 1 1 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain F-box PF00646.33 EAQ92509.1 - 0.00047 20.0 0.0 0.00091 19.0 0.0 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EAQ92509.1 - 0.034 14.1 0.2 0.077 12.9 0.2 1.6 1 0 0 1 1 1 0 F-box-like Lambda_CIII PF02061.16 EAQ92509.1 - 0.04 14.0 0.1 0.087 12.9 0.1 1.6 1 0 0 1 1 1 0 Lambda Phage CIII PIF1 PF05970.14 EAQ92510.1 - 2.3e-18 66.5 0.1 4.5e-18 65.6 0.1 1.3 1 0 0 1 1 1 1 PIF1-like helicase HTH_psq PF05225.16 EAQ92510.1 - 7.5e-10 38.4 0.2 1.8e-09 37.2 0.2 1.7 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.16 EAQ92510.1 - 1.4e-08 34.6 0.0 2.7e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain AAA_30 PF13604.6 EAQ92510.1 - 2.7e-06 27.2 0.3 1.9e-05 24.5 0.0 2.5 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.6 EAQ92510.1 - 0.043 14.2 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain UvrD_C_2 PF13538.6 EAQ92510.1 - 0.047 13.5 0.0 0.13 12.1 0.0 1.8 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Pectate_lyase_3 PF12708.7 EAQ92511.1 - 2.6e-76 256.2 6.6 8.8e-64 215.3 1.2 2.8 2 0 0 2 2 2 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 EAQ92511.1 - 2.9e-06 26.9 4.9 0.019 14.7 0.2 2.9 3 0 0 3 3 3 2 N terminal extension of bacteriophage endosialidase DNase_NucA_NucB PF14040.6 EAQ92511.1 - 5.1e-05 23.6 0.4 0.00022 21.6 0.0 2.3 2 0 0 2 2 2 1 Deoxyribonuclease NucA/NucB CFEM PF05730.11 EAQ92512.1 - 1.7e-34 117.7 30.6 6.3e-14 51.8 5.4 5.3 5 0 0 5 5 5 3 CFEM domain Chitin_bind_1 PF00187.19 EAQ92512.1 - 0.0019 18.6 18.7 0.0019 18.6 18.7 7.6 8 1 1 9 9 9 3 Chitin recognition protein ABC_tran PF00005.27 EAQ92513.1 - 0.15 12.5 0.0 0.21 12.1 0.0 1.3 1 0 0 1 1 1 0 ABC transporter WD40 PF00400.32 EAQ92514.1 - 5.6e-65 213.7 30.3 4.4e-11 43.2 0.2 8.2 8 0 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAQ92514.1 - 2.1e-29 101.6 3.3 8.9e-07 29.1 0.0 6.6 1 1 5 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EAQ92514.1 - 1.1e-13 50.9 0.5 0.0095 14.9 0.0 6.0 1 1 4 6 6 6 3 WD40 region of Ge1, enhancer of mRNA-decapping protein IKI3 PF04762.12 EAQ92514.1 - 2.4e-10 39.2 2.1 4.5e-05 21.7 0.1 2.6 1 1 2 3 3 3 2 IKI3 family eIF2A PF08662.11 EAQ92514.1 - 2.7e-10 40.5 0.0 4.6e-05 23.4 0.0 3.2 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 EAQ92514.1 - 5.6e-08 31.9 9.8 0.16 10.6 0.0 5.7 3 2 3 6 6 6 4 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 EAQ92514.1 - 3e-06 26.4 22.5 0.041 12.8 0.1 5.3 2 2 4 6 6 6 5 Partner and localizer of BRCA2 WD40 domain PD40 PF07676.12 EAQ92514.1 - 4.2e-06 26.6 11.9 3.6 7.6 0.1 5.9 6 0 0 6 6 5 4 WD40-like Beta Propeller Repeat Nbas_N PF15492.6 EAQ92514.1 - 5.5e-05 22.6 2.5 2.6 7.3 0.0 4.4 2 2 2 4 4 4 1 Neuroblastoma-amplified sequence, N terminal Frtz PF11768.8 EAQ92514.1 - 5.8e-05 21.6 0.0 0.12 10.7 0.0 2.7 2 1 1 3 3 3 2 WD repeat-containing and planar cell polarity effector protein Fritz Cytochrom_D1 PF02239.16 EAQ92514.1 - 0.0015 17.1 0.0 0.063 11.8 0.0 2.8 2 2 1 3 3 3 1 Cytochrome D1 heme domain WD40_like PF17005.5 EAQ92514.1 - 0.0034 16.8 0.0 12 5.1 0.0 3.2 2 1 1 3 3 3 1 WD40-like domain Proteasome_A_N PF10584.9 EAQ92514.1 - 0.19 11.4 3.2 93 2.8 0.1 5.2 6 0 0 6 6 6 0 Proteasome subunit A N-terminal signature Myb_DNA-bind_6 PF13921.6 EAQ92515.1 - 0.0003 21.0 0.0 0.00054 20.2 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EAQ92515.1 - 0.06 13.6 0.2 0.11 12.7 0.2 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain Mis14 PF08641.12 EAQ92515.1 - 0.15 12.3 3.1 0.25 11.6 3.1 1.3 1 0 0 1 1 1 0 Kinetochore protein Mis14 like Pox_Ag35 PF03286.14 EAQ92516.1 - 0.012 15.4 2.3 0.012 15.4 2.3 3.0 3 0 0 3 3 3 0 Pox virus Ag35 surface protein C1_2 PF03107.16 EAQ92516.1 - 0.28 11.5 4.1 0.71 10.2 4.1 1.7 1 0 0 1 1 1 0 C1 domain Zn_ribbon_17 PF17120.5 EAQ92516.1 - 1.2 8.9 7.1 2.2 7.9 7.1 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-B_box PF00643.24 EAQ92516.1 - 1.3 9.3 4.6 3.3 7.9 4.6 1.7 1 0 0 1 1 1 0 B-box zinc finger ABC_tran PF00005.27 EAQ92517.1 - 1.4e-52 177.9 0.0 1.9e-32 112.6 0.0 2.8 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EAQ92517.1 - 2.5e-32 112.6 33.7 5.7e-26 91.8 18.1 3.2 3 1 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 EAQ92517.1 - 6.6e-08 32.2 0.2 0.01 15.3 0.0 3.9 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EAQ92517.1 - 3.1e-05 24.3 0.0 1.7 8.9 0.0 3.7 3 0 0 3 3 3 2 AAA domain AAA_23 PF13476.6 EAQ92517.1 - 3.6e-05 24.4 1.0 0.032 14.7 0.1 2.4 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 EAQ92517.1 - 0.00014 21.5 1.0 0.4 10.4 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EAQ92517.1 - 0.00042 20.4 0.4 0.15 12.1 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EAQ92517.1 - 0.00059 19.8 0.0 0.37 10.7 0.0 3.0 3 0 0 3 3 3 1 RsgA GTPase AAA_25 PF13481.6 EAQ92517.1 - 0.0006 19.4 0.2 4.7 6.7 0.0 3.5 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 EAQ92517.1 - 0.001 19.5 2.6 0.83 10.0 0.3 3.1 2 2 0 2 2 2 2 AAA ATPase domain DUF87 PF01935.17 EAQ92517.1 - 0.001 19.2 5.6 0.028 14.5 0.1 2.4 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_21 PF13304.6 EAQ92517.1 - 0.0013 18.6 0.1 13 5.5 0.0 3.9 4 0 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system T2SSE PF00437.20 EAQ92517.1 - 0.0042 16.2 0.0 0.078 12.0 0.0 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein Zeta_toxin PF06414.12 EAQ92517.1 - 0.0047 16.2 0.0 1.2 8.4 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin NACHT PF05729.12 EAQ92517.1 - 0.047 13.6 1.0 3.8 7.4 0.5 2.5 2 0 0 2 2 2 0 NACHT domain MeaB PF03308.16 EAQ92517.1 - 0.077 12.0 0.1 0.22 10.5 0.0 1.7 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NB-ARC PF00931.22 EAQ92517.1 - 0.1 11.8 3.1 1.4 8.1 0.1 3.0 3 0 0 3 3 3 0 NB-ARC domain SbcCD_C PF13558.6 EAQ92517.1 - 0.13 12.5 0.0 20 5.5 0.0 3.4 3 0 0 3 3 3 0 Putative exonuclease SbcCD, C subunit DUF2075 PF09848.9 EAQ92517.1 - 0.33 10.1 1.3 1.6 7.9 0.1 2.5 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) CbiA PF01656.23 EAQ92517.1 - 4.2 7.4 6.7 11 6.1 0.6 3.1 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short_C2 PF13561.6 EAQ92518.1 - 1.6e-54 185.0 0.0 2.1e-54 184.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EAQ92518.1 - 8e-44 149.4 0.0 1e-43 149.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EAQ92518.1 - 6e-11 42.6 0.0 8e-11 42.2 0.0 1.1 1 0 0 1 1 1 1 KR domain PALP PF00291.25 EAQ92518.1 - 0.045 13.2 0.0 0.063 12.7 0.0 1.1 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme DUF1776 PF08643.10 EAQ92518.1 - 0.065 12.6 0.0 0.095 12.1 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Cytochrom_C1 PF02167.15 EAQ92520.1 - 2e-94 315.4 0.0 2.4e-94 315.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 EAQ92520.1 - 0.0083 16.4 0.0 0.017 15.4 0.0 1.6 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III DAHP_synth_1 PF00793.20 EAQ92521.1 - 1.1e-101 339.3 0.0 1.3e-101 339.1 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family Pro_isomerase PF00160.21 EAQ92522.1 - 2.4e-50 170.9 0.3 6.8e-50 169.4 0.0 1.9 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 EAQ92522.1 - 2.4e-08 34.5 0.0 0.0012 19.7 0.0 4.9 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAQ92522.1 - 0.0095 16.2 0.0 0.11 12.8 0.0 2.6 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EAQ92522.1 - 0.047 12.6 0.6 5 6.0 0.1 3.1 3 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein FMN_dh PF01070.18 EAQ92523.1 - 1.7e-117 392.4 0.1 2e-117 392.2 0.1 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 EAQ92523.1 - 0.00035 19.7 1.3 0.0032 16.5 0.3 2.2 1 1 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 EAQ92523.1 - 0.00035 19.8 0.5 0.00055 19.2 0.5 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.15 EAQ92523.1 - 0.0054 16.2 2.7 0.0076 15.7 2.7 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase ThiG PF05690.14 EAQ92523.1 - 0.1 11.9 1.4 0.27 10.5 0.3 2.0 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG Nup84_Nup100 PF04121.13 EAQ92524.1 - 1.5e-203 678.0 0.1 1.8e-203 677.7 0.1 1.1 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 MTCP1 PF08991.10 EAQ92525.1 - 1.1e-26 92.9 5.2 1.2e-26 92.7 5.2 1.0 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type CHCH PF06747.13 EAQ92525.1 - 0.0014 18.7 5.6 0.0014 18.7 5.6 1.7 2 0 0 2 2 2 1 CHCH domain COX17 PF05051.13 EAQ92525.1 - 0.019 15.3 1.7 0.033 14.5 1.7 1.4 1 0 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.10 EAQ92525.1 - 0.042 13.9 4.0 0.095 12.7 4.0 1.7 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Rad60-SLD PF11976.8 EAQ92526.1 - 2e-19 69.2 0.1 2.4e-19 68.9 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EAQ92526.1 - 2e-11 43.4 0.1 2.3e-11 43.3 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin family HI0933_like PF03486.14 EAQ92526.1 - 0.026 13.2 0.2 0.028 13.1 0.2 1.1 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_8 PF13450.6 EAQ92526.1 - 0.042 14.1 0.0 0.062 13.5 0.0 1.4 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain LIM PF00412.22 EAQ92527.1 - 1.4e-17 63.7 12.4 7.8e-09 35.6 5.5 2.6 2 0 0 2 2 2 2 LIM domain DUF2321 PF10083.9 EAQ92527.1 - 0.0068 16.1 2.6 0.017 14.7 0.1 2.2 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2321) zf-dskA_traR PF01258.17 EAQ92527.1 - 0.056 13.4 0.2 0.056 13.4 0.2 3.7 4 0 0 4 4 4 0 Prokaryotic dksA/traR C4-type zinc finger DZR PF12773.7 EAQ92527.1 - 1.7 8.7 21.3 1.6 8.8 9.3 3.4 1 1 2 3 3 3 0 Double zinc ribbon Nudix_N_2 PF14803.6 EAQ92527.1 - 8 6.5 15.3 3.9 7.5 1.0 4.8 5 0 0 5 5 5 0 Nudix N-terminal MFS_1 PF07690.16 EAQ92529.1 - 8.4e-16 57.8 39.6 5.3e-15 55.2 38.8 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 EAQ92529.1 - 0.07 11.7 24.7 0.02 13.5 15.2 2.0 1 1 1 2 2 2 0 MFS/sugar transport protein Ligase_CoA PF00549.19 EAQ92530.1 - 8.4e-26 90.6 2.3 1.5e-15 57.3 0.0 3.4 2 1 0 2 2 2 2 CoA-ligase CoA_binding PF02629.19 EAQ92530.1 - 9.5e-13 48.7 0.3 6.2e-12 46.0 0.4 2.4 2 0 0 2 2 2 1 CoA binding domain Succ_CoA_lig PF13607.6 EAQ92530.1 - 4.1e-08 33.1 0.7 3.4e-05 23.7 0.1 3.0 3 1 0 3 3 3 2 Succinyl-CoA ligase like flavodoxin domain Dynamin_M PF01031.20 EAQ92531.1 - 1.5e-109 365.6 0.0 2.7e-109 364.8 0.0 1.4 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 EAQ92531.1 - 3.1e-52 177.0 0.0 6.9e-52 175.9 0.0 1.6 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 EAQ92531.1 - 2.4e-31 107.7 2.4 2.4e-31 107.7 2.4 2.0 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 EAQ92531.1 - 0.00012 22.2 0.2 0.0012 18.9 0.2 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 EAQ92531.1 - 0.085 13.1 0.0 1.9 8.7 0.0 2.7 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase Condensin2nSMC PF12422.8 EAQ92531.1 - 0.18 12.0 0.1 7.1 6.8 0.1 2.5 2 0 0 2 2 2 0 Condensin II non structural maintenance of chromosomes subunit WD40 PF00400.32 EAQ92532.1 - 4.7e-58 191.8 24.7 1.2e-11 44.9 0.4 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAQ92532.1 - 8.6e-26 90.1 0.5 2.4e-05 24.5 0.1 5.8 1 1 4 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EAQ92532.1 - 9.2e-14 51.1 0.3 0.0036 16.3 0.0 5.6 1 1 5 6 6 6 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 EAQ92532.1 - 1.3e-09 38.2 0.0 5.7e-06 26.3 0.0 2.3 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.12 EAQ92532.1 - 2e-08 32.8 1.1 0.00045 18.4 0.2 2.1 1 1 1 2 2 2 2 IKI3 family PD40 PF07676.12 EAQ92532.1 - 3.3e-08 33.3 5.9 1.2 9.1 0.1 5.6 5 0 0 5 5 5 3 WD40-like Beta Propeller Repeat Nup160 PF11715.8 EAQ92532.1 - 4.1e-08 32.3 2.2 0.19 10.3 0.0 4.9 3 2 2 5 5 5 3 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 EAQ92532.1 - 4.8e-07 29.0 11.6 0.028 13.3 0.3 4.0 2 2 2 4 4 4 3 Partner and localizer of BRCA2 WD40 domain Nbas_N PF15492.6 EAQ92532.1 - 4.7e-05 22.9 2.9 1.3 8.3 0.0 4.3 2 2 2 4 4 4 1 Neuroblastoma-amplified sequence, N terminal Frtz PF11768.8 EAQ92532.1 - 0.00034 19.1 0.0 0.05 11.9 0.0 2.1 2 0 0 2 2 2 2 WD repeat-containing and planar cell polarity effector protein Fritz DUF1513 PF07433.11 EAQ92532.1 - 0.017 14.2 0.5 2.1 7.4 0.0 2.9 1 1 1 3 3 3 0 Protein of unknown function (DUF1513) Cytochrom_D1 PF02239.16 EAQ92532.1 - 0.018 13.6 0.0 0.86 8.1 0.0 2.7 2 1 1 3 3 3 0 Cytochrome D1 heme domain DPPIV_N PF00930.21 EAQ92532.1 - 0.02 13.7 3.5 10 4.7 0.0 4.3 3 2 1 5 5 5 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Proteasome_A_N PF10584.9 EAQ92532.1 - 0.038 13.7 4.2 80 3.1 0.1 5.6 6 0 0 6 6 6 0 Proteasome subunit A N-terminal signature Coatomer_WDAD PF04053.14 EAQ92532.1 - 0.15 11.0 0.0 1.5 7.8 0.0 2.1 2 1 0 2 2 2 0 Coatomer WD associated region Peptidase_S9_N PF02897.15 EAQ92532.1 - 0.34 9.7 0.5 4.8 5.9 0.2 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase, N-terminal beta-propeller domain Pectate_lyase_3 PF12708.7 EAQ92534.1 - 2e-74 250.0 12.7 9e-64 215.2 1.7 2.8 3 0 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 EAQ92534.1 - 6.9e-06 25.7 5.2 0.021 14.5 0.1 3.1 3 0 0 3 3 3 2 N terminal extension of bacteriophage endosialidase DNase_NucA_NucB PF14040.6 EAQ92534.1 - 4.5e-05 23.8 0.4 0.00022 21.6 0.0 2.3 2 0 0 2 2 2 1 Deoxyribonuclease NucA/NucB CFEM PF05730.11 EAQ92535.1 - 3.3e-34 116.8 31.3 1.2e-13 50.9 6.1 5.3 5 0 0 5 5 5 3 CFEM domain Chitin_bind_1 PF00187.19 EAQ92535.1 - 0.0007 20.0 18.5 0.0007 20.0 18.5 7.7 8 1 0 8 8 8 3 Chitin recognition protein LysM PF01476.20 EAQ92535.1 - 0.15 12.2 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 LysM domain p450 PF00067.22 EAQ92536.1 - 3.6e-66 223.8 0.0 1.1e-51 176.1 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 Ribonuc_L-PSP PF01042.21 EAQ92539.1 - 1.7e-41 141.0 0.1 2.1e-41 140.7 0.1 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP PMT_4TMC PF16192.5 EAQ92540.1 - 2.9e-68 229.4 10.9 2.9e-68 229.4 10.9 3.4 2 1 0 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase PMT PF02366.18 EAQ92540.1 - 5.1e-64 216.2 16.6 3.9e-59 200.2 13.8 2.6 2 1 1 3 3 3 2 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.19 EAQ92540.1 - 3e-19 69.6 0.8 9.1e-19 68.0 0.8 1.8 1 1 1 2 2 2 2 MIR domain PMT_2 PF13231.6 EAQ92540.1 - 0.013 15.8 10.3 0.013 15.8 10.3 2.8 4 1 0 4 4 4 0 Dolichyl-phosphate-mannose-protein mannosyltransferase zf-C2H2 PF00096.26 EAQ92541.1 - 0.0072 16.7 2.7 0.0072 16.7 2.7 2.8 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 EAQ92541.1 - 0.042 13.6 0.6 0.042 13.6 0.6 2.8 3 0 0 3 3 3 0 C2H2-type zinc-finger domain Helicase_C PF00271.31 EAQ92543.1 - 2e-23 82.8 0.1 4.9e-23 81.6 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EAQ92543.1 - 3.3e-23 82.5 0.0 8e-23 81.3 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAQ92543.1 - 1.4e-15 57.5 0.0 4.1e-15 56.0 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 EAQ92543.1 - 0.0021 17.8 0.0 0.0045 16.7 0.0 1.4 1 0 0 1 1 1 1 SWI2/SNF2 ATPase AAA_22 PF13401.6 EAQ92543.1 - 0.0028 18.0 0.0 0.012 15.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain LRR_9 PF14580.6 EAQ92544.1 - 1.2e-09 37.9 0.0 2.1e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 Leucine-rich repeat NTF2 PF02136.20 EAQ92544.1 - 3.1e-05 24.5 0.0 5.6e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain LRR_4 PF12799.7 EAQ92544.1 - 8.8e-05 22.8 0.0 0.002 18.5 0.0 2.5 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) RRM_9 PF18444.1 EAQ92544.1 - 0.00023 21.0 0.0 0.00064 19.5 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif LRR_6 PF13516.6 EAQ92544.1 - 0.014 15.4 0.3 0.087 12.9 0.1 2.5 3 0 0 3 3 3 0 Leucine Rich repeat LRR_8 PF13855.6 EAQ92544.1 - 0.024 14.4 0.0 0.057 13.2 0.0 1.7 1 0 0 1 1 1 0 Leucine rich repeat SARAF PF06682.12 EAQ92545.1 - 0.0064 16.2 6.9 0.022 14.4 6.8 1.8 1 1 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis Kelch_5 PF13854.6 EAQ92545.1 - 0.087 12.8 1.5 1.4 8.9 0.1 3.3 4 0 0 4 4 4 0 Kelch motif HLH PF00010.26 EAQ92546.1 - 6.8e-16 58.0 0.0 1.4e-15 57.0 0.0 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Spt20 PF12090.8 EAQ92546.1 - 0.1 12.2 18.6 0.01 15.5 13.8 1.9 2 0 0 2 2 2 0 Spt20 family MSC PF09402.10 EAQ92547.1 - 3.6e-113 378.4 0.0 4.8e-113 378.1 0.0 1.1 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.7 EAQ92547.1 - 2.4e-17 62.3 0.1 6e-17 61.1 0.0 1.7 2 0 0 2 2 2 1 HeH/LEM domain Thymopoietin PF08198.11 EAQ92547.1 - 0.0012 18.4 0.0 0.0034 16.9 0.0 1.7 1 0 0 1 1 1 1 Thymopoietin protein Dermcidin PF15291.6 EAQ92547.1 - 0.093 13.3 0.2 0.093 13.3 0.2 2.1 2 0 0 2 2 2 0 Dermcidin, antibiotic peptide SYCE1 PF15233.6 EAQ92547.1 - 0.097 12.7 0.5 0.2 11.7 0.5 1.4 1 0 0 1 1 1 0 Synaptonemal complex central element protein 1 HisG PF01634.18 EAQ92548.1 - 3.6e-56 189.6 0.0 9.6e-56 188.2 0.0 1.7 2 0 0 2 2 2 1 ATP phosphoribosyltransferase HisG_C PF08029.11 EAQ92548.1 - 5.4e-28 96.9 0.3 1.2e-27 95.8 0.3 1.6 1 0 0 1 1 1 1 HisG, C-terminal domain MFS_2 PF13347.6 EAQ92549.1 - 3.7e-08 32.4 4.0 3.7e-08 32.4 4.0 2.5 2 1 0 2 2 2 1 MFS/sugar transport protein MFS_1_like PF12832.7 EAQ92549.1 - 0.00012 21.1 0.2 0.00012 21.1 0.2 1.8 2 1 0 2 2 2 1 MFS_1 like family Sel1 PF08238.12 EAQ92550.1 - 1.4e-37 127.3 29.0 3.8e-05 24.2 0.1 7.6 7 0 0 7 7 7 7 Sel1 repeat TPR_6 PF13174.6 EAQ92550.1 - 0.0072 16.9 0.9 16 6.4 0.0 4.4 3 1 1 4 4 4 2 Tetratricopeptide repeat Chitin_synth_2 PF03142.15 EAQ92552.1 - 2.2e-247 821.9 5.9 2.7e-199 663.2 0.2 2.1 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 EAQ92552.1 - 5.8e-14 52.5 7.4 3.3e-13 50.0 7.4 2.1 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EAQ92552.1 - 5.7e-10 39.5 0.0 9.3e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 EAQ92552.1 - 9.8e-05 21.9 0.0 0.0027 17.2 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 EAQ92552.1 - 0.023 14.5 0.0 0.05 13.4 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 2 DUF2415 PF10313.9 EAQ92553.1 - 0.015 15.2 0.0 0.46 10.5 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised protein domain (DUF2415) WD40 PF00400.32 EAQ92553.1 - 0.04 14.8 1.7 0.49 11.3 0.9 3.0 2 0 0 2 2 2 0 WD domain, G-beta repeat DNA_pol_phi PF04931.13 EAQ92553.1 - 8.2 4.4 13.8 11 3.9 13.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi Glyco_hydro_17 PF00332.18 EAQ92554.1 - 0.22 11.1 0.5 0.42 10.1 0.2 1.5 2 0 0 2 2 2 0 Glycosyl hydrolases family 17 RNB PF00773.19 EAQ92555.1 - 3.1e-65 220.6 0.0 5.6e-65 219.8 0.0 1.4 1 0 0 1 1 1 1 RNB domain FliJ PF02050.16 EAQ92555.1 - 0.00071 19.8 0.6 0.0014 18.9 0.6 1.4 1 0 0 1 1 1 1 Flagellar FliJ protein Sec10 PF07393.11 EAQ92556.1 - 1.7e-234 780.5 4.6 2e-234 780.3 4.6 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 DUF5099 PF17025.5 EAQ92557.1 - 0.004 17.5 0.0 0.0059 17.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5099) Prenyltransf PF01255.19 EAQ92557.1 - 0.0043 16.6 0.0 0.0056 16.2 0.0 1.2 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Met_10 PF02475.16 EAQ92558.1 - 3.8e-63 212.8 0.0 5.9e-63 212.2 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein DUF1752 PF08550.10 EAQ92559.1 - 9.1e-11 41.4 5.7 2.1e-10 40.3 5.7 1.7 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) DUF4611 PF15387.6 EAQ92559.1 - 0.19 12.0 3.4 0.69 10.2 0.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) PBP1_TM PF14812.6 EAQ92559.1 - 1.2 9.6 10.5 5.7 7.4 1.8 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Proteasome PF00227.26 EAQ92560.1 - 7.2e-47 159.3 0.2 8.6e-47 159.1 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Peptidase_M22 PF00814.25 EAQ92561.1 - 5.2e-44 151.0 0.0 7.9e-43 147.1 0.0 2.2 1 1 0 1 1 1 1 Glycoprotease family FGGY_C PF02782.16 EAQ92561.1 - 0.15 11.8 0.0 0.36 10.5 0.0 1.6 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain Glyco_transf_34 PF05637.12 EAQ92562.1 - 3.2e-44 151.5 0.1 2.2e-43 148.7 0.1 2.0 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Glyco_hydro_16 PF00722.21 EAQ92563.1 - 3.5e-06 26.6 0.0 7.2e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Ank_4 PF13637.6 EAQ92564.1 - 1.8e-27 95.4 0.0 2.1e-09 37.7 0.0 4.7 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAQ92564.1 - 2.6e-27 95.2 0.0 7.1e-14 52.2 0.0 3.0 2 1 1 3 3 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAQ92564.1 - 3.9e-21 74.8 0.6 4.1e-08 33.3 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EAQ92564.1 - 1.8e-20 72.4 0.0 0.00067 20.0 0.0 6.0 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 EAQ92564.1 - 2.6e-17 61.1 0.0 0.011 16.2 0.0 6.2 6 0 0 6 6 5 4 Ankyrin repeat NACHT PF05729.12 EAQ92564.1 - 2.7e-06 27.4 0.1 8.9e-06 25.7 0.1 1.8 1 1 0 1 1 1 1 NACHT domain DUF676 PF05057.14 EAQ92564.1 - 0.00098 18.7 0.0 0.002 17.7 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) AAA_16 PF13191.6 EAQ92564.1 - 0.0024 18.3 0.0 0.0068 16.8 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain Abhydrolase_6 PF12697.7 EAQ92564.1 - 0.0053 17.4 0.1 0.015 15.9 0.1 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family AAA_22 PF13401.6 EAQ92564.1 - 0.012 15.9 0.0 0.039 14.2 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_30 PF13604.6 EAQ92564.1 - 0.036 13.8 0.0 0.076 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EAQ92564.1 - 0.081 12.7 0.3 0.48 10.2 0.2 2.3 1 1 1 2 2 2 0 P-loop containing region of AAA domain AAA_19 PF13245.6 EAQ92564.1 - 0.11 12.8 0.0 0.3 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EAQ92564.1 - 0.11 12.6 0.1 0.23 11.6 0.1 1.5 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 EAQ92564.1 - 0.12 12.0 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Viral_helicase1 PF01443.18 EAQ92564.1 - 0.13 12.0 0.1 0.24 11.1 0.1 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.27 EAQ92564.1 - 0.15 12.6 0.0 0.41 11.1 0.0 1.7 1 0 0 1 1 1 0 ABC transporter PGAP1 PF07819.13 EAQ92564.1 - 0.15 11.8 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein AAA_18 PF13238.6 EAQ92564.1 - 0.16 12.5 0.0 0.43 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EAQ92564.1 - 0.18 11.0 0.1 0.38 10.0 0.1 1.5 1 0 0 1 1 1 0 Zeta toxin Abhydrolase_2 PF02230.16 EAQ92565.1 - 2e-22 80.1 0.3 1.3e-15 57.8 0.1 2.3 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase FSH1 PF03959.13 EAQ92565.1 - 0.017 14.8 0.0 0.09 12.4 0.0 2.3 1 1 0 1 1 1 0 Serine hydrolase (FSH1) ZapB PF06005.12 EAQ92565.1 - 0.031 14.7 5.6 0.31 11.5 3.1 2.5 2 1 0 2 2 2 0 Cell division protein ZapB Hydrolase_4 PF12146.8 EAQ92565.1 - 0.042 13.1 0.2 2.4 7.4 0.0 2.5 1 1 1 2 2 2 0 Serine aminopeptidase, S33 DUF2203 PF09969.9 EAQ92565.1 - 0.052 14.3 6.5 0.12 13.1 0.5 2.5 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Abhydrolase_3 PF07859.13 EAQ92565.1 - 0.065 13.1 0.0 0.16 11.8 0.0 1.7 1 0 0 1 1 1 0 alpha/beta hydrolase fold Type_III_YscX PF09474.10 EAQ92565.1 - 0.11 12.8 1.3 0.36 11.1 1.1 2.0 1 1 1 2 2 2 0 Type III secretion system YscX (type_III_YscX) Peptidase_S9 PF00326.21 EAQ92565.1 - 0.16 11.5 0.9 0.82 9.1 0.9 2.1 1 1 0 1 1 1 0 Prolyl oligopeptidase family HAP1_N PF04849.13 EAQ92565.1 - 0.66 9.1 13.8 1.1 8.4 13.8 1.2 1 0 0 1 1 1 0 HAP1 N-terminal conserved region TPR_MLP1_2 PF07926.12 EAQ92565.1 - 0.85 9.7 15.7 0.28 11.2 7.7 2.4 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Noelin-1 PF12308.8 EAQ92565.1 - 1 9.3 5.9 7.8 6.5 0.8 2.7 2 1 0 2 2 2 0 Neurogenesis glycoprotein DUF3500 PF12006.8 EAQ92566.1 - 1.2e-93 313.8 0.0 1.5e-93 313.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3500) Med16 PF11635.8 EAQ92567.1 - 7e-39 133.4 0.0 1.3e-24 86.2 0.1 2.0 1 1 1 2 2 2 2 Mediator complex subunit 16 Ribosomal_60s PF00428.19 EAQ92567.1 - 2.7 8.7 6.7 0.36 11.4 2.2 1.9 2 0 0 2 2 2 0 60s Acidic ribosomal protein SIR2 PF02146.17 EAQ92568.1 - 6e-28 98.0 0.0 2.4e-27 96.0 0.0 1.8 1 1 0 1 1 1 1 Sir2 family SNF2_N PF00176.23 EAQ92569.1 - 9.6e-58 195.6 0.0 1.6e-57 194.8 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.24 EAQ92569.1 - 1.6e-26 91.9 1.7 5.5e-17 61.4 0.4 3.3 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.31 EAQ92569.1 - 7.5e-20 71.3 0.0 2e-19 70.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4208 PF13907.6 EAQ92569.1 - 1.9e-12 47.5 0.4 1e-11 45.1 0.0 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF4208) ResIII PF04851.15 EAQ92569.1 - 1.4e-07 31.7 0.0 1.3e-06 28.5 0.0 2.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 EAQ92569.1 - 9.7e-07 28.2 2.3 9.8e-07 28.2 0.0 2.2 2 1 0 2 2 1 1 Class II histone deacetylase complex subunits 2 and 3 Cdh1_DBD_1 PF18196.1 EAQ92569.1 - 0.00044 20.5 0.3 0.00044 20.5 0.3 5.7 5 1 1 6 6 6 1 Chromodomain helicase DNA-binding domain 1 SLIDE PF09111.10 EAQ92569.1 - 0.018 15.1 4.5 0.11 12.5 0.0 3.2 3 0 0 3 3 2 0 SLIDE CHDCT2 PF08074.11 EAQ92569.1 - 0.024 14.8 0.7 0.38 10.9 0.0 2.9 2 1 0 2 2 2 0 CHDCT2 (NUC038) domain CDH1_2_SANT_HL1 PF18375.1 EAQ92569.1 - 0.042 14.5 4.7 0.051 14.3 0.9 3.2 2 0 0 2 2 2 0 CDH1/2 SANT-Helical linker 1 POR PF01558.18 EAQ92569.1 - 0.05 13.7 0.2 0.17 12.0 0.0 1.9 2 0 0 2 2 2 0 Pyruvate ferredoxin/flavodoxin oxidoreductase ABC_tran PF00005.27 EAQ92570.1 - 4e-16 59.8 0.0 1.5e-06 28.8 0.0 2.8 3 0 0 3 3 2 2 ABC transporter AAA_16 PF13191.6 EAQ92570.1 - 1.2e-07 32.2 0.0 0.0067 16.8 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 EAQ92570.1 - 5e-07 29.8 2.4 0.087 12.6 1.1 3.6 3 1 0 4 4 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 EAQ92570.1 - 1e-05 26.0 0.0 0.011 16.1 0.1 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EAQ92570.1 - 1.9e-05 25.0 0.0 0.0041 17.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 EAQ92570.1 - 2e-05 24.5 0.0 0.14 11.9 0.0 2.6 3 0 0 3 3 3 2 AAA ATPase domain AAA_23 PF13476.6 EAQ92570.1 - 9.2e-05 23.0 0.0 0.033 14.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EAQ92570.1 - 0.00031 20.7 0.0 0.76 9.7 0.0 2.7 3 0 0 3 3 3 2 RsgA GTPase AAA_18 PF13238.6 EAQ92570.1 - 0.00032 21.2 0.0 1.4 9.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 EAQ92570.1 - 0.00036 20.2 0.2 0.48 10.2 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain Rad17 PF03215.15 EAQ92570.1 - 0.00051 20.0 0.0 0.057 13.3 0.0 2.3 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_24 PF13479.6 EAQ92570.1 - 0.00058 19.6 0.1 0.22 11.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 EAQ92570.1 - 0.00066 20.0 0.1 0.3 11.5 0.0 2.5 2 0 0 2 2 2 1 RNA helicase Thymidylate_kin PF02223.17 EAQ92570.1 - 0.00091 18.9 0.2 0.92 9.1 0.1 2.8 3 0 0 3 3 3 2 Thymidylate kinase SRP54 PF00448.22 EAQ92570.1 - 0.0011 18.6 2.4 0.058 13.0 0.1 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_7 PF12775.7 EAQ92570.1 - 0.0013 18.3 0.2 0.048 13.2 0.1 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_28 PF13521.6 EAQ92570.1 - 0.0013 19.0 0.5 0.16 12.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 EAQ92570.1 - 0.0018 17.7 0.5 3.9 6.8 0.0 3.2 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain NACHT PF05729.12 EAQ92570.1 - 0.002 18.1 1.9 0.18 11.7 0.0 2.7 2 0 0 2 2 2 1 NACHT domain AAA_13 PF13166.6 EAQ92570.1 - 0.0025 16.5 0.4 0.0047 15.6 0.0 1.6 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 EAQ92570.1 - 0.0037 17.3 0.0 0.057 13.4 0.0 2.3 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE NB-ARC PF00931.22 EAQ92570.1 - 0.0037 16.5 0.0 0.29 10.3 0.0 2.2 2 0 0 2 2 2 1 NB-ARC domain AAA_33 PF13671.6 EAQ92570.1 - 0.0043 17.2 0.9 0.49 10.6 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 EAQ92570.1 - 0.0049 16.9 0.3 0.3 11.1 0.0 2.7 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 EAQ92570.1 - 0.027 14.2 0.2 1.6 8.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain VirE PF05272.11 EAQ92570.1 - 0.029 14.1 0.0 6.7 6.4 0.0 2.5 2 0 0 2 2 2 0 Virulence-associated protein E PduV-EutP PF10662.9 EAQ92570.1 - 0.038 13.7 2.0 0.15 11.8 0.0 2.9 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation CLP1_P PF16575.5 EAQ92570.1 - 0.12 12.1 0.6 0.81 9.5 0.0 2.3 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_14 PF13173.6 EAQ92570.1 - 0.13 12.3 0.5 19 5.3 0.0 2.9 2 1 0 2 2 2 0 AAA domain CbiA PF01656.23 EAQ92570.1 - 0.15 12.2 0.1 4.7 7.3 0.0 2.8 3 0 0 3 3 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain MMR_HSR1 PF01926.23 EAQ92570.1 - 0.18 11.9 1.3 25 5.0 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase NTPase_1 PF03266.15 EAQ92570.1 - 0.2 11.6 3.4 2.2 8.2 0.1 2.7 3 0 0 3 3 3 0 NTPase MukB PF04310.12 EAQ92570.1 - 0.25 11.1 0.9 30 4.3 0.0 2.7 3 0 0 3 3 3 0 MukB N-terminal FF PF01846.19 EAQ92571.1 - 1.7e-50 169.0 7.1 5.2e-13 49.0 0.2 6.9 6 1 0 6 6 6 5 FF domain WW PF00397.26 EAQ92571.1 - 6.6e-18 64.5 14.3 8.4e-11 41.8 2.9 2.6 2 0 0 2 2 2 2 WW domain RhoGAP-FF1 PF16512.5 EAQ92571.1 - 0.0014 19.3 10.5 0.65 10.7 0.1 4.5 4 0 0 4 4 4 2 p190-A and -B Rho GAPs FF domain HycH PF07450.11 EAQ92571.1 - 0.065 13.6 0.1 0.19 12.1 0.1 1.8 1 0 0 1 1 1 0 Formate hydrogenlyase maturation protein HycH Glyco_hyd_101C PF17451.2 EAQ92571.1 - 1.1 9.5 4.3 10 6.4 0.1 2.8 1 1 1 2 2 2 0 Glycosyl hydrolase 101 beta sandwich domain Trs65 PF12735.7 EAQ92572.1 - 1.3e-77 261.3 0.0 1.8e-77 260.9 0.0 1.1 1 0 0 1 1 1 1 TRAPP trafficking subunit Trs65 SLD3 PF08639.10 EAQ92573.1 - 3.1e-189 630.2 1.1 5.2e-189 629.5 1.1 1.3 1 0 0 1 1 1 1 DNA replication regulator SLD3 Pkinase PF00069.25 EAQ92574.1 - 3.4e-22 79.1 0.0 7e-22 78.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ92574.1 - 2.3e-13 50.0 0.0 4.4e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase NOG1_N PF17835.1 EAQ92574.1 - 0.36 10.8 5.4 0.48 10.4 0.1 3.3 3 0 0 3 3 3 0 NOG1 N-terminal helical domain Homeodomain PF00046.29 EAQ92575.1 - 3.6e-15 55.6 1.5 6.6e-15 54.7 1.5 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 EAQ92575.1 - 0.00025 20.9 0.1 0.0011 18.8 0.1 2.1 2 0 0 2 2 2 1 Homeobox KN domain YdaS_antitoxin PF15943.5 EAQ92575.1 - 0.18 11.7 0.0 0.37 10.7 0.0 1.4 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HAD_2 PF13419.6 EAQ92577.1 - 2.2e-17 63.7 0.0 3.6e-15 56.5 0.0 2.1 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EAQ92577.1 - 8e-09 36.1 0.0 0.00033 21.0 0.0 2.2 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EAQ92577.1 - 1e-05 25.5 0.0 2e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like GHL6 PF14871.6 EAQ92577.1 - 0.16 12.1 0.0 0.3 11.2 0.0 1.4 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase 6 GN3L_Grn1 PF08701.11 EAQ92578.1 - 8.3e-25 86.7 17.3 1.7e-24 85.7 17.3 1.5 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.23 EAQ92578.1 - 1.3e-16 60.7 0.1 5.1e-12 45.9 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EAQ92578.1 - 4.6e-06 26.6 0.0 0.00011 22.2 0.0 2.2 1 1 0 1 1 1 1 RsgA GTPase GTP_EFTU PF00009.27 EAQ92578.1 - 7e-06 25.7 0.0 0.026 14.0 0.0 2.6 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 EAQ92578.1 - 3.6e-05 23.9 4.3 0.18 11.9 0.1 3.6 2 2 0 3 3 3 2 Dynamin family FeoB_N PF02421.18 EAQ92578.1 - 0.003 17.1 0.1 0.028 13.9 0.0 2.4 2 1 0 2 2 2 1 Ferrous iron transport protein B MeaB PF03308.16 EAQ92578.1 - 0.05 12.6 1.9 0.066 12.2 0.0 2.1 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Nuc_deoxyri_tr2 PF15891.5 EAQ92578.1 - 0.071 13.4 1.4 0.88 9.9 0.0 2.5 2 0 0 2 2 2 0 Nucleoside 2-deoxyribosyltransferase like AAA_18 PF13238.6 EAQ92578.1 - 0.23 12.0 0.0 0.23 12.0 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EAQ92578.1 - 0.32 11.3 0.0 0.32 11.3 0.0 3.1 2 1 0 2 2 2 0 AAA ATPase domain Nop14 PF04147.12 EAQ92578.1 - 0.51 8.5 23.3 0.78 7.9 23.3 1.2 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 EAQ92578.1 - 1.8 7.8 22.7 3.1 7.1 22.7 1.3 1 0 0 1 1 1 0 BUD22 NOA36 PF06524.12 EAQ92578.1 - 4 6.7 18.3 7.4 5.8 18.3 1.4 1 0 0 1 1 1 0 NOA36 protein CNDH2_C PF16858.5 EAQ92578.1 - 5.7 6.7 14.5 10 5.9 14.5 1.3 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term RNB PF00773.19 EAQ92579.1 - 4.5e-97 325.3 0.0 7.9e-97 324.5 0.0 1.4 1 0 0 1 1 1 1 RNB domain Rrp44_S1 PF17215.3 EAQ92579.1 - 6.1e-31 106.2 0.2 1.7e-30 104.8 0.0 1.9 2 0 0 2 2 2 1 S1 domain Rrp44_CSD1 PF17216.3 EAQ92579.1 - 8.1e-29 100.2 0.1 2.9e-28 98.4 0.1 1.9 1 1 0 1 1 1 1 Rrp44-like cold shock domain OB_Dis3 PF17849.1 EAQ92579.1 - 8.8e-20 70.5 0.0 2e-19 69.4 0.0 1.7 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) PIN_4 PF13638.6 EAQ92579.1 - 4.8e-10 39.8 1.5 7.7e-10 39.2 0.0 2.2 2 0 0 2 2 2 1 PIN domain CSD2 PF17876.1 EAQ92579.1 - 7.6e-08 32.4 0.1 0.0008 19.5 0.0 3.0 2 0 0 2 2 2 2 Cold shock domain OB_RNB PF08206.11 EAQ92579.1 - 0.091 12.5 0.0 0.31 10.8 0.0 1.9 1 0 0 1 1 1 0 Ribonuclease B OB domain Dynein_heavy PF03028.15 EAQ92580.1 - 0.061 13.4 0.0 0.094 12.8 0.0 1.3 1 0 0 1 1 1 0 Dynein heavy chain region D6 P-loop domain CRC_subunit PF08624.10 EAQ92581.1 - 1.2e-51 174.7 0.0 1.7e-51 174.2 0.0 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit CBFD_NFYB_HMF PF00808.23 EAQ92582.1 - 3e-06 27.4 0.1 4.6e-06 26.8 0.1 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EAQ92582.1 - 0.00046 20.5 6.1 0.0014 18.9 0.1 2.1 1 1 1 2 2 2 1 Core histone H2A/H2B/H3/H4 eIF3_subunit PF08597.10 EAQ92582.1 - 0.008 16.1 0.9 0.0099 15.8 0.9 1.1 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit DUF3915 PF13054.6 EAQ92582.1 - 0.11 12.5 0.1 0.15 12.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Bromo_TP PF07524.13 EAQ92582.1 - 0.12 12.4 0.0 0.19 11.8 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated Gram_pos_anchor PF00746.21 EAQ92583.1 - 0.18 11.7 1.7 0.43 10.5 0.3 2.1 2 0 0 2 2 2 0 LPXTG cell wall anchor motif Aldedh PF00171.22 EAQ92585.1 - 1.7e-107 359.8 0.0 2.1e-107 359.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family HLH PF00010.26 EAQ92586.1 - 1.3e-12 47.5 0.2 2.8e-12 46.4 0.2 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF601 PF04642.12 EAQ92586.1 - 0.15 11.6 4.6 0.23 10.9 4.6 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF601 TEBP_beta PF07404.11 EAQ92586.1 - 1.8 7.9 7.2 2.9 7.1 7.2 1.3 1 0 0 1 1 1 0 Telomere-binding protein beta subunit (TEBP beta) PhoD PF09423.10 EAQ92587.1 - 0.00038 19.6 0.1 0.0029 16.7 0.1 2.3 3 0 0 3 3 3 1 PhoD-like phosphatase Rhomboid PF01694.22 EAQ92588.1 - 4.7e-26 91.6 8.5 9.2e-26 90.6 8.5 1.5 1 0 0 1 1 1 1 Rhomboid family HTH_28 PF13518.6 EAQ92588.1 - 0.043 14.0 0.2 2 8.6 0.0 2.8 2 0 0 2 2 2 0 Helix-turn-helix domain DUF3558 PF12079.8 EAQ92589.1 - 8.3 6.4 14.2 36 4.3 14.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3558) PVL_ORF50 PF07768.11 EAQ92590.1 - 0.077 13.3 0.9 0.077 13.3 0.9 2.2 3 0 0 3 3 3 0 PVL ORF-50-like family IU_nuc_hydro PF01156.19 EAQ92592.1 - 6.7e-55 186.8 0.0 1.2e-54 185.9 0.0 1.3 1 1 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase DUF2188 PF09954.9 EAQ92592.1 - 0.04 14.1 0.0 0.086 13.0 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2188) HpcH_HpaI PF03328.14 EAQ92593.1 - 6.2e-20 71.3 0.0 5.9e-19 68.1 0.0 1.9 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family CHORD PF04968.12 EAQ92594.1 - 1.5e-44 150.5 21.1 1.8e-25 89.4 6.1 2.3 2 0 0 2 2 2 2 CHORD CS PF04969.16 EAQ92594.1 - 1.8e-13 51.3 0.0 2.7e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 CS domain DUF1467 PF07330.12 EAQ92595.1 - 0.03 14.3 0.0 0.079 12.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1467) WH2 PF02205.20 EAQ92597.1 - 2.5e-11 43.0 0.3 2.5e-11 43.0 0.3 2.8 3 0 0 3 3 3 1 WH2 motif RRM_1 PF00076.22 EAQ92600.1 - 8.2e-40 134.5 0.0 1.1e-18 66.8 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 EAQ92600.1 - 0.054 13.3 0.1 1.2 8.9 0.0 2.9 3 0 0 3 3 3 0 Rrp7 RRM-like N-terminal domain RRM_7 PF16367.5 EAQ92600.1 - 0.079 13.1 0.0 2.5 8.3 0.0 2.6 2 0 0 2 2 2 0 RNA recognition motif NDUFB10 PF10249.9 EAQ92601.1 - 0.012 16.2 0.0 0.013 15.9 0.0 1.2 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit 10 HWE_HK PF07536.14 EAQ92601.1 - 0.068 13.9 0.0 0.1 13.3 0.0 1.3 1 0 0 1 1 1 0 HWE histidine kinase Ribosomal_L37 PF08561.10 EAQ92602.1 - 8.6e-41 139.2 0.2 1.4e-40 138.6 0.2 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L37 FXR_C1 PF16096.5 EAQ92602.1 - 0.024 14.8 0.0 0.059 13.6 0.0 1.6 1 0 0 1 1 1 0 Fragile X-related 1 protein C-terminal region 2 TAFII55_N PF04658.13 EAQ92603.1 - 3.3e-49 166.7 0.0 6.8e-49 165.7 0.0 1.6 1 0 0 1 1 1 1 TAFII55 protein conserved region DUF3245 PF11595.8 EAQ92603.1 - 2.5 8.6 18.5 5 7.6 0.6 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3245) DTHCT PF08070.11 EAQ92603.1 - 4.9 7.9 10.7 3 8.6 2.5 3.2 2 0 0 2 2 2 0 DTHCT (NUC029) region FAM176 PF14851.6 EAQ92603.1 - 9.4 5.9 23.1 0.74 9.5 4.5 3.3 3 0 0 3 3 3 0 FAM176 family Bromo_TP PF07524.13 EAQ92604.1 - 8.9e-07 28.8 0.0 2.2e-06 27.6 0.0 1.6 2 0 0 2 2 2 1 Bromodomain associated TFIID-31kDa PF02291.15 EAQ92604.1 - 0.041 14.0 0.0 0.057 13.5 0.0 1.4 1 1 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Glyco_hydro_15 PF00723.21 EAQ92605.1 - 9.1e-53 179.6 0.0 1.6e-50 172.2 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 15 TPT PF03151.16 EAQ92606.1 - 2.8e-11 43.3 5.3 3.9e-11 42.9 5.3 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EAQ92606.1 - 0.0028 17.8 7.7 0.0028 17.8 7.7 2.9 2 1 1 3 3 3 2 EamA-like transporter family RRM_1 PF00076.22 EAQ92607.1 - 4.1e-17 61.7 0.1 6.3e-17 61.2 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 6PGD PF00393.19 EAQ92608.1 - 3.2e-127 423.9 0.0 3.9e-127 423.6 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 EAQ92608.1 - 1.7e-43 148.5 0.0 2.8e-43 147.8 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 EAQ92608.1 - 0.12 12.6 0.0 0.38 11.0 0.0 1.9 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase SWI-SNF_Ssr4 PF08549.10 EAQ92609.1 - 9.5e-244 811.3 8.8 4.9e-146 488.3 1.4 2.1 1 1 1 2 2 2 2 Fungal domain of unknown function (DUF1750) Ribosomal_S17_N PF16205.5 EAQ92610.1 - 2e-33 114.6 0.2 3.2e-33 113.9 0.2 1.3 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 EAQ92610.1 - 1.9e-14 53.5 0.1 3.7e-14 52.6 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S17 Spc7_N PF15402.6 EAQ92611.1 - 5.8e-104 349.2 48.5 5.8e-80 269.8 39.0 3.0 1 1 1 2 2 2 2 N-terminus of kinetochore NMS complex subunit Spc7 Spc7 PF08317.11 EAQ92612.1 - 1.1e-92 310.3 12.4 1.9e-92 309.5 12.4 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein Spc7_N PF15402.6 EAQ92612.1 - 3.4e-70 237.5 20.6 4.9e-70 236.9 20.6 1.2 1 0 0 1 1 1 1 N-terminus of kinetochore NMS complex subunit Spc7 Spc7_C2 PF15577.6 EAQ92612.1 - 5.1e-17 61.7 0.1 9.7e-17 60.8 0.1 1.5 1 0 0 1 1 1 1 Spc7_C2 Laminin_II PF06009.12 EAQ92612.1 - 0.056 13.5 2.5 0.12 12.3 2.5 1.6 1 0 0 1 1 1 0 Laminin Domain II KxDL PF10241.9 EAQ92612.1 - 0.074 13.3 3.8 0.12 12.7 1.6 2.4 3 0 0 3 3 3 0 Uncharacterized conserved protein kleA_kleC PF17383.2 EAQ92612.1 - 0.12 12.7 4.2 0.34 11.2 4.2 1.7 1 0 0 1 1 1 0 Uncharacterized KorC regulated protein A Herpes_UL25 PF01499.16 EAQ92612.1 - 0.14 10.7 2.8 0.22 10.0 2.8 1.2 1 0 0 1 1 1 0 Herpesvirus UL25 family Scaffolding_pro PF11418.8 EAQ92612.1 - 0.14 12.7 1.6 0.28 11.8 0.9 1.8 2 0 0 2 2 2 0 Phi29 scaffolding protein ING PF12998.7 EAQ92612.1 - 0.15 12.6 3.6 0.34 11.5 0.4 2.8 2 1 1 3 3 2 0 Inhibitor of growth proteins N-terminal histone-binding Exonuc_VII_L PF02601.15 EAQ92612.1 - 0.28 10.7 4.9 0.52 9.8 4.9 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit V_ATPase_I PF01496.19 EAQ92612.1 - 0.33 8.8 3.9 0.5 8.2 3.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Syntaxin PF00804.25 EAQ92612.1 - 0.5 10.0 9.2 0.25 11.0 6.0 2.0 1 1 1 2 2 2 0 Syntaxin MotA_ExbB PF01618.16 EAQ92612.1 - 0.8 9.5 3.5 1.3 8.8 0.1 2.6 2 0 0 2 2 2 0 MotA/TolQ/ExbB proton channel family HAUS6_N PF14661.6 EAQ92612.1 - 0.81 9.2 5.5 1.6 8.2 5.5 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF4201 PF13870.6 EAQ92612.1 - 3 7.6 12.4 0.026 14.3 4.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) FlaC_arch PF05377.11 EAQ92613.1 - 2.4 8.6 5.5 4.9 7.6 0.7 2.6 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Atg14 PF10186.9 EAQ92614.1 - 6.7e-56 189.7 3.6 7.7e-54 182.9 2.7 2.1 1 1 1 2 2 2 2 Vacuolar sorting 38 and autophagy-related subunit 14 Spc7 PF08317.11 EAQ92614.1 - 0.0096 14.8 1.5 0.013 14.4 1.5 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein PUA_3 PF17785.1 EAQ92614.1 - 0.042 13.7 0.0 0.084 12.7 0.0 1.6 1 0 0 1 1 1 0 PUA-like domain AAA_13 PF13166.6 EAQ92614.1 - 0.064 11.9 0.5 0.081 11.6 0.5 1.1 1 0 0 1 1 1 0 AAA domain TMPIT PF07851.13 EAQ92614.1 - 0.069 12.4 0.5 0.094 12.0 0.5 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF4407 PF14362.6 EAQ92614.1 - 0.083 12.2 4.9 0.13 11.6 4.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Golgin_A5 PF09787.9 EAQ92614.1 - 0.096 12.1 4.8 0.14 11.6 4.8 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 T3SSipB PF16535.5 EAQ92614.1 - 0.12 12.8 5.5 0.2 12.1 5.5 1.3 1 0 0 1 1 1 0 Type III cell invasion protein SipB Jnk-SapK_ap_N PF09744.9 EAQ92614.1 - 0.2 11.9 4.3 0.31 11.3 4.3 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Spectrin PF00435.21 EAQ92614.1 - 0.27 11.8 2.9 0.47 11.0 2.9 1.4 1 0 0 1 1 1 0 Spectrin repeat APG6_N PF17675.1 EAQ92614.1 - 9.4 6.8 9.7 20 5.7 9.7 1.5 1 1 0 1 1 1 0 Apg6 coiled-coil region APC_u14 PF16635.5 EAQ92615.1 - 1 9.9 6.5 0.19 12.3 3.3 1.5 2 0 0 2 2 2 0 Unstructured region on APC between SAMP and APC_crr DUF3807 PF12720.7 EAQ92616.1 - 4.4e-57 193.3 6.0 5e-57 193.1 6.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3807) DNA_pol_alpha_N PF12254.8 EAQ92616.1 - 3.5 7.8 12.3 1.4 9.1 0.1 3.3 2 2 1 3 3 3 0 DNA polymerase alpha subunit p180 N terminal NAD_binding_1 PF00175.21 EAQ92617.1 - 1e-32 113.0 0.0 2.4e-32 111.8 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 EAQ92617.1 - 7.8e-22 77.5 0.0 1.5e-21 76.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 EAQ92617.1 - 4.1e-09 36.7 0.0 0.00025 21.2 0.0 2.6 3 0 0 3 3 3 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 EAQ92617.1 - 0.11 12.8 0.0 0.34 11.1 0.0 1.9 3 0 0 3 3 3 0 Siderophore-interacting FAD-binding domain SH3_1 PF00018.28 EAQ92618.1 - 8.7e-09 34.9 0.1 1.5e-08 34.1 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EAQ92618.1 - 8.3e-08 32.0 0.2 1.8e-07 30.9 0.2 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EAQ92618.1 - 3e-05 23.6 0.0 5.2e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Ssu72 PF04722.13 EAQ92620.1 - 1.3e-80 269.5 0.0 1.5e-80 269.3 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein GIT_SHD PF08518.11 EAQ92621.1 - 8.4e-25 86.1 5.2 3.4e-13 48.9 1.9 2.6 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT DUF4407 PF14362.6 EAQ92621.1 - 0.092 12.1 30.9 17 4.7 6.1 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) APG6_N PF17675.1 EAQ92621.1 - 0.12 12.9 40.2 0.28 11.7 13.5 2.6 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF5082 PF16888.5 EAQ92621.1 - 0.19 12.0 25.1 0.66 10.3 9.1 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) CLZ PF16526.5 EAQ92621.1 - 0.26 11.7 18.7 0.51 10.7 0.4 3.9 2 2 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Lebercilin PF15619.6 EAQ92621.1 - 0.26 10.9 32.8 2.2 7.9 21.0 2.6 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease UPF0242 PF06785.11 EAQ92621.1 - 0.6 10.2 30.3 0.75 9.9 15.1 2.5 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus AAA_13 PF13166.6 EAQ92621.1 - 0.82 8.2 19.7 1.5 7.4 19.7 1.4 1 0 0 1 1 1 0 AAA domain FUSC PF04632.12 EAQ92621.1 - 2 6.9 15.4 4 5.8 15.4 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family Helo_like_N PF17111.5 EAQ92621.1 - 2.3 7.5 10.7 0.33 10.3 3.1 2.6 2 1 0 3 3 3 0 Fungal N-terminal domain of STAND proteins Uso1_p115_C PF04871.13 EAQ92621.1 - 2.8 8.3 39.3 2.6 8.4 14.5 4.0 3 1 1 5 5 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region Lectin_N PF03954.14 EAQ92621.1 - 2.9 7.6 8.9 19 5.0 0.1 3.1 2 1 0 2 2 2 0 Hepatic lectin, N-terminal domain Golgin_A5 PF09787.9 EAQ92621.1 - 3.2 7.1 30.0 17 4.8 30.2 2.0 1 1 0 1 1 1 0 Golgin subfamily A member 5 Spc7 PF08317.11 EAQ92621.1 - 4.3 6.1 33.0 2.9 6.7 15.5 2.8 2 1 1 3 3 3 0 Spc7 kinetochore protein DUF2229 PF09989.9 EAQ92621.1 - 5.7 6.5 5.3 6.1 6.4 3.7 1.8 1 1 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) Prefoldin PF02996.17 EAQ92621.1 - 6 6.8 24.8 1.8 8.5 0.6 4.6 3 1 1 4 4 4 0 Prefoldin subunit Fez1 PF06818.15 EAQ92621.1 - 6.8 7.1 30.8 22 5.5 9.3 2.5 1 1 1 2 2 2 0 Fez1 DUF3584 PF12128.8 EAQ92621.1 - 7.1 4.0 30.6 11 3.4 30.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) MARVEL PF01284.23 EAQ92622.1 - 1.1e-08 35.2 3.2 1.8e-08 34.5 3.2 1.4 1 0 0 1 1 1 1 Membrane-associating domain TFR_dimer PF04253.15 EAQ92623.1 - 5.3e-34 116.9 0.1 1e-33 116.0 0.1 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 EAQ92623.1 - 9.5e-19 67.9 0.0 2.8e-18 66.4 0.0 1.7 2 0 0 2 2 2 1 Peptidase family M28 PA PF02225.22 EAQ92623.1 - 3.8e-08 33.3 0.6 1e-07 31.9 0.1 2.0 2 0 0 2 2 2 1 PA domain BLOC1_2 PF10046.9 EAQ92623.1 - 0.0067 16.7 1.0 0.2 12.0 0.1 2.4 2 0 0 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Trimer_CC PF08954.11 EAQ92623.1 - 0.019 14.5 0.3 0.038 13.5 0.3 1.5 1 0 0 1 1 1 0 Trimerisation motif Apolipoprotein PF01442.18 EAQ92623.1 - 0.025 14.4 1.5 0.044 13.7 1.5 1.3 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Cytochrom_C_2 PF01322.20 EAQ92623.1 - 1.6 9.7 3.8 1.1 10.1 1.9 1.7 2 0 0 2 2 2 0 Cytochrome C' MFS_1 PF07690.16 EAQ92624.1 - 5.4e-26 91.4 35.0 6.1e-17 61.6 11.8 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EAQ92624.1 - 3.8e-06 26.0 5.8 3.8e-06 26.0 5.8 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter RasGAP_C PF03836.15 EAQ92625.1 - 1.6e-44 151.4 1.5 1.6e-44 151.4 1.5 2.4 3 0 0 3 3 3 1 RasGAP C-terminus RasGAP PF00616.19 EAQ92625.1 - 2.1e-30 106.0 0.0 8.7e-15 55.0 0.0 2.7 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase IQ PF00612.27 EAQ92625.1 - 2.5e-20 70.3 33.7 0.034 13.9 0.8 13.7 14 0 0 14 14 14 8 IQ calmodulin-binding motif CH PF00307.31 EAQ92625.1 - 4.1e-11 43.0 0.0 1.4e-10 41.3 0.0 2.0 1 0 0 1 1 1 1 Calponin homology (CH) domain ASL_C PF08328.11 EAQ92625.1 - 2.4 8.3 4.8 5 7.2 0.9 3.1 2 0 0 2 2 2 0 Adenylosuccinate lyase C-terminal IMPDH PF00478.25 EAQ92626.1 - 1.4e-127 425.4 6.2 1.7e-127 425.2 6.2 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 EAQ92626.1 - 3.6e-16 59.3 0.1 5e-08 33.3 0.1 2.5 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.18 EAQ92626.1 - 5.3e-09 35.6 2.2 1.6e-07 30.7 1.0 2.2 2 0 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.15 EAQ92626.1 - 1.5e-08 34.4 3.0 0.001 18.5 2.7 2.4 2 0 0 2 2 2 2 Nitronate monooxygenase His_biosynth PF00977.21 EAQ92626.1 - 0.00013 21.5 2.7 0.01 15.3 0.4 2.4 1 1 1 2 2 2 2 Histidine biosynthesis protein PK PF00224.21 EAQ92626.1 - 0.035 13.0 0.0 0.15 11.0 0.0 2.0 2 1 1 3 3 3 0 Pyruvate kinase, barrel domain YpsA PF06908.11 EAQ92626.1 - 0.12 12.4 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 YspA SLOG family AlaDh_PNT_N PF05222.15 EAQ92627.1 - 2.7e-30 105.5 0.0 4.1e-30 104.8 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.21 EAQ92627.1 - 0.0052 16.1 0.4 0.013 14.8 0.0 1.8 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Fungal_trans PF04082.18 EAQ92628.1 - 3.7e-09 36.0 0.2 8.8e-09 34.8 0.2 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EAQ92628.1 - 0.0028 17.8 5.4 0.0057 16.8 5.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3395 PF11875.8 EAQ92629.1 - 1.6e-05 24.8 0.1 3.4e-05 23.8 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3395) DnaJ PF00226.31 EAQ92629.1 - 0.028 14.5 0.0 0.075 13.2 0.0 1.8 1 0 0 1 1 1 0 DnaJ domain Pkinase PF00069.25 EAQ92630.1 - 2.8e-62 210.5 0.0 3.6e-62 210.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ92630.1 - 3.9e-16 59.1 0.0 6.7e-16 58.4 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EAQ92630.1 - 2.2e-05 24.5 0.2 0.077 12.9 0.2 3.0 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EAQ92630.1 - 0.036 12.8 0.0 0.057 12.2 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase V-SNARE PF05008.15 EAQ92631.1 - 2.5e-21 75.8 2.4 2.5e-21 75.8 2.4 2.1 2 1 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.8 EAQ92631.1 - 1.8e-13 50.6 2.5 1.8e-13 50.6 2.5 2.0 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 EAQ92631.1 - 0.018 14.9 2.5 0.022 14.7 0.7 2.1 2 1 0 2 2 2 0 Sec20 Use1 PF09753.9 EAQ92631.1 - 0.057 13.1 6.3 0.85 9.3 6.3 2.6 1 1 0 1 1 1 0 Membrane fusion protein Use1 YqjK PF13997.6 EAQ92631.1 - 0.21 11.8 6.6 0.6 10.4 0.2 3.2 3 0 0 3 3 3 0 YqjK-like protein zf-C4H2 PF10146.9 EAQ92631.1 - 1.3 9.3 4.0 1.6 9.0 0.3 2.0 1 1 0 2 2 2 0 Zinc finger-containing protein DUF4713 PF15831.5 EAQ92631.1 - 5.1 7.6 6.2 8.7 6.9 3.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4713) APG6 PF04111.12 EAQ92632.1 - 7.7e-58 195.4 0.0 1.3e-57 194.7 0.0 1.3 1 0 0 1 1 1 1 Apg6 BARA domain APG6_N PF17675.1 EAQ92632.1 - 8.8e-38 129.8 11.3 1.6e-37 129.0 11.3 1.4 1 0 0 1 1 1 1 Apg6 coiled-coil region BBS2_C PF14782.6 EAQ92632.1 - 0.016 14.0 1.4 0.023 13.5 1.4 1.1 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal GCN5L1 PF06320.13 EAQ92632.1 - 0.055 13.6 3.4 0.11 12.7 3.4 1.5 1 0 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) DUF3450 PF11932.8 EAQ92632.1 - 0.066 12.5 11.5 0.14 11.4 10.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF2514 PF10721.9 EAQ92632.1 - 0.19 11.7 8.5 0.22 11.5 6.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2514) FUSC PF04632.12 EAQ92632.1 - 0.32 9.5 3.3 0.42 9.1 3.3 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family HAUS-augmin3 PF14932.6 EAQ92632.1 - 0.35 10.4 14.3 0.067 12.8 9.3 1.9 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 CENP-F_leu_zip PF10473.9 EAQ92632.1 - 0.39 10.7 11.8 2.8 8.0 11.8 2.1 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FapA PF03961.13 EAQ92632.1 - 0.46 9.0 2.1 0.67 8.5 2.1 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A KASH_CCD PF14662.6 EAQ92632.1 - 0.46 10.3 9.8 0.76 9.6 9.8 1.3 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH V_ATPase_I PF01496.19 EAQ92632.1 - 0.67 7.8 2.2 0.89 7.4 2.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spc7 PF08317.11 EAQ92632.1 - 0.87 8.4 9.3 1.8 7.4 9.3 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein Uds1 PF15456.6 EAQ92632.1 - 1.4 9.1 10.1 0.87 9.8 7.0 2.1 1 1 1 2 2 2 0 Up-regulated During Septation YlqD PF11068.8 EAQ92632.1 - 3.2 8.1 6.9 6.5 7.1 6.9 1.5 1 0 0 1 1 1 0 YlqD protein Glyco_hydro_45 PF02015.16 EAQ92633.1 - 3.5e-75 252.5 20.2 4.1e-75 252.3 20.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 Het-C PF07217.11 EAQ92634.1 - 1.9e-206 686.9 1.6 2.2e-106 356.6 0.0 2.0 1 1 1 2 2 2 2 Heterokaryon incompatibility protein Het-C Metallothio_2 PF01439.18 EAQ92634.1 - 0.12 13.2 1.4 0.32 11.9 1.4 1.7 1 0 0 1 1 1 0 Metallothionein ALIX_LYPXL_bnd PF13949.6 EAQ92634.1 - 0.14 11.4 0.6 0.22 10.8 0.6 1.2 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV DASH_Ask1 PF08655.10 EAQ92634.1 - 0.2 11.5 0.6 1.5 8.8 0.1 2.3 2 0 0 2 2 2 0 DASH complex subunit Ask1 HMG_box PF00505.19 EAQ92636.1 - 1.4e-05 25.4 0.0 3.4e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EAQ92636.1 - 0.001 19.6 0.0 0.0031 18.1 0.0 1.8 1 0 0 1 1 1 1 HMG-box domain Urease_alpha PF00449.20 EAQ92637.1 - 3.3e-55 185.6 4.7 6.3e-55 184.7 2.4 2.5 3 0 0 3 3 3 1 Urease alpha-subunit, N-terminal domain Urease_beta PF00699.20 EAQ92637.1 - 3.3e-37 126.4 0.0 5.7e-37 125.7 0.0 1.4 1 0 0 1 1 1 1 Urease beta subunit Urease_gamma PF00547.18 EAQ92637.1 - 1.9e-27 95.5 0.0 4.4e-27 94.3 0.0 1.7 1 1 0 1 1 1 1 Urease, gamma subunit Amidohydro_1 PF01979.20 EAQ92637.1 - 3.9e-25 88.9 0.1 6.4e-25 88.2 0.1 1.2 1 0 0 1 1 1 1 Amidohydrolase family Maf PF02545.14 EAQ92639.1 - 3.9e-42 143.9 0.0 1.1e-41 142.5 0.0 1.8 1 1 0 1 1 1 1 Maf-like protein tRNA-synt_2b PF00587.25 EAQ92639.1 - 1.1e-32 113.4 0.0 5.2e-31 108.0 0.0 2.2 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EAQ92639.1 - 0.00083 19.5 0.0 0.0016 18.6 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain Ribosomal_S3_C PF00189.20 EAQ92639.1 - 0.064 13.8 0.0 0.16 12.5 0.0 1.7 1 0 0 1 1 1 0 Ribosomal protein S3, C-terminal domain Glyco_hydro_47 PF01532.20 EAQ92640.1 - 6.3e-172 572.6 0.0 7.6e-172 572.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Utp11 PF03998.13 EAQ92641.1 - 7.5e-50 170.2 8.9 8.3e-50 170.0 8.9 1.0 1 0 0 1 1 1 1 Utp11 protein SLATT_5 PF18160.1 EAQ92641.1 - 0.09 12.1 0.3 0.15 11.4 0.3 1.2 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 DAO PF01266.24 EAQ92643.1 - 1e-33 117.4 5.5 1.3e-33 117.0 5.5 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EAQ92643.1 - 6.4e-05 23.4 1.0 0.00015 22.2 1.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EAQ92643.1 - 0.00012 21.5 0.1 0.00019 20.8 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EAQ92643.1 - 0.00064 19.1 0.2 0.001 18.4 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 EAQ92643.1 - 0.0013 17.9 0.3 0.0021 17.2 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain ApbA PF02558.16 EAQ92643.1 - 0.0017 18.0 0.0 0.0029 17.3 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.6 EAQ92643.1 - 0.0018 18.7 0.0 0.0035 17.8 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding NAD_binding_8 PF13450.6 EAQ92643.1 - 0.0036 17.5 2.1 0.0093 16.2 1.4 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.18 EAQ92643.1 - 0.0058 16.5 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 EAQ92643.1 - 0.023 14.0 0.0 0.035 13.4 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 EAQ92643.1 - 0.045 13.3 0.1 0.069 12.7 0.1 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain GIDA PF01134.22 EAQ92643.1 - 0.13 11.3 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 EAQ92643.1 - 0.15 11.3 0.0 0.31 10.3 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase fn3 PF00041.21 EAQ92644.1 - 4.8e-07 30.0 0.2 1.5e-06 28.4 0.0 2.0 2 0 0 2 2 2 1 Fibronectin type III domain MbeD_MobD PF04899.12 EAQ92644.1 - 1.1 9.4 6.0 0.46 10.6 0.1 2.8 2 1 1 3 3 3 0 MbeD/MobD like Tht1 PF04163.12 EAQ92644.1 - 3.5 6.3 3.8 5.1 5.7 3.8 1.1 1 0 0 1 1 1 0 Tht1-like nuclear fusion protein DUF4047 PF13256.6 EAQ92644.1 - 5.5 7.2 9.4 16 5.7 9.5 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4047) Exonuc_VII_L PF02601.15 EAQ92644.1 - 7.5 6.0 13.5 12 5.3 13.5 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit LNS2 PF08235.13 EAQ92645.1 - 6e-93 310.5 0.0 8e-93 310.1 0.0 1.2 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 EAQ92645.1 - 2.7e-42 142.9 0.0 7.1e-42 141.5 0.0 1.7 2 0 0 2 2 2 1 lipin, N-terminal conserved region Acid_phosphat_B PF03767.14 EAQ92645.1 - 0.00057 19.5 0.0 0.035 13.7 0.0 2.6 2 0 0 2 2 2 1 HAD superfamily, subfamily IIIB (Acid phosphatase) TFIID-31kDa PF02291.15 EAQ92646.1 - 7e-19 68.1 0.0 1e-18 67.5 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit SPATA3 PF15662.5 EAQ92646.1 - 1.1 9.9 21.0 1.5 9.4 21.0 1.3 1 0 0 1 1 1 0 Spermatogenesis-associated protein 3 family CCDC53 PF10152.9 EAQ92646.1 - 3.4 8.1 13.5 5.8 7.3 13.5 1.4 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex DUF4551 PF15087.6 EAQ92646.1 - 4.2 6.1 8.4 4.6 5.9 8.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Pex14_N PF04695.13 EAQ92646.1 - 4.4 7.9 24.9 7.2 7.2 24.9 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PAT1 PF09770.9 EAQ92646.1 - 4.5 5.4 8.6 4.7 5.4 8.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SPX PF03105.19 EAQ92646.1 - 6.1 6.7 11.1 7 6.4 11.1 1.1 1 0 0 1 1 1 0 SPX domain Trypan_PARP PF05887.11 EAQ92646.1 - 7.6 6.5 14.6 10 6.1 14.6 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Histidinol_dh PF00815.20 EAQ92647.1 - 7.1e-128 427.1 8.2 1.2e-99 334.2 4.6 2.2 1 1 1 2 2 2 2 Histidinol dehydrogenase PRA-CH PF01502.18 EAQ92647.1 - 1.1e-24 86.0 0.1 2.3e-24 85.0 0.1 1.6 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.17 EAQ92647.1 - 1.3e-11 44.8 1.7 1.9e-11 44.3 0.1 2.1 2 0 0 2 2 2 1 Phosphoribosyl-ATP pyrophosphohydrolase PLA2_B PF01735.18 EAQ92648.1 - 1.8e-175 584.1 0.0 2.2e-175 583.8 0.0 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain DUF3176 PF11374.8 EAQ92650.1 - 1.1e-24 86.6 1.2 2.2e-23 82.5 0.0 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF3176) Cation_efflux PF01545.21 EAQ92651.1 - 8.3e-50 169.3 10.3 3.8e-49 167.1 10.3 1.8 1 1 0 1 1 1 1 Cation efflux family GST_N PF02798.20 EAQ92652.1 - 5.9e-14 52.2 0.0 9.2e-14 51.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EAQ92652.1 - 8.2e-14 51.8 0.0 1.4e-13 51.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EAQ92652.1 - 1.5e-10 41.2 0.0 4.3e-10 39.7 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EAQ92652.1 - 4.5e-09 36.5 0.0 9.4e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EAQ92652.1 - 3.5e-08 33.5 0.0 6.2e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EAQ92652.1 - 6.7e-05 22.8 0.1 0.00011 22.1 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 EAQ92652.1 - 0.018 15.8 0.0 0.07 13.9 0.0 1.8 2 0 0 2 2 2 0 Glutathione S-transferase N-terminal domain GST_C_5 PF16865.5 EAQ92652.1 - 0.056 14.0 0.0 0.11 13.1 0.0 1.5 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain F-box-like PF12937.7 EAQ92653.1 - 2.1e-07 30.7 0.0 4.3e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EAQ92653.1 - 0.00077 19.3 0.0 0.0044 16.9 0.1 2.1 2 0 0 2 2 2 1 F-box domain TPR_1 PF00515.28 EAQ92653.1 - 0.014 15.2 0.0 0.32 10.9 0.0 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 EAQ92653.1 - 0.039 14.1 0.0 3 8.2 0.0 2.7 1 1 1 2 2 2 0 Tetratricopeptide repeat MBOAT PF03062.19 EAQ92654.1 - 3.3e-47 161.5 12.1 3.3e-47 161.5 12.1 1.5 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family DUF2613 PF11021.8 EAQ92655.1 - 0.041 14.0 2.8 0.082 13.0 2.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) Prefoldin_3 PF13758.6 EAQ92657.1 - 7.9e-34 115.7 0.4 2.6e-33 114.0 0.4 1.9 1 0 0 1 1 1 1 Prefoldin subunit DUF3835 PF12927.7 EAQ92657.1 - 2.8e-20 72.9 8.8 4.3e-17 62.7 0.0 5.0 5 0 0 5 5 5 2 Domain of unknown function (DUF3835) MIS13 PF08202.11 EAQ92657.1 - 0.00048 19.5 1.5 0.00048 19.5 1.5 1.9 2 0 0 2 2 2 1 Mis12-Mtw1 protein family DUF16 PF01519.16 EAQ92657.1 - 5.2 7.6 7.6 13 6.3 0.0 3.4 4 0 0 4 4 4 0 Protein of unknown function DUF16 CS PF04969.16 EAQ92658.1 - 1e-17 64.9 0.5 3.8e-17 63.1 0.0 2.1 3 0 0 3 3 3 1 CS domain MAT1 PF06391.13 EAQ92659.1 - 1.1e-36 126.6 0.3 1.4e-36 126.3 0.3 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_5 PF17121.5 EAQ92659.1 - 5.5e-32 109.4 11.1 8.2e-32 108.9 11.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EAQ92659.1 - 0.00025 20.9 5.4 0.00056 19.7 5.4 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EAQ92659.1 - 0.00035 20.3 6.4 0.00053 19.8 6.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EAQ92659.1 - 0.0053 16.6 6.9 0.019 14.8 7.1 1.8 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) MRP-S26 PF14943.6 EAQ92659.1 - 0.0062 16.5 12.3 0.0097 15.8 12.3 1.3 1 0 0 1 1 1 1 Mitochondrial ribosome subunit S26 zf-RING_2 PF13639.6 EAQ92659.1 - 0.011 16.1 6.9 0.017 15.4 6.9 1.3 1 0 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.6 EAQ92659.1 - 0.013 15.4 9.4 0.22 11.5 9.9 2.2 1 1 1 2 2 2 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 EAQ92659.1 - 0.031 14.3 5.9 0.057 13.4 5.9 1.5 1 0 0 1 1 1 0 RING-type zinc-finger Zn_ribbon_17 PF17120.5 EAQ92659.1 - 0.12 12.0 2.2 0.24 11.1 2.2 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type DUF3797 PF12677.7 EAQ92659.1 - 0.19 11.6 3.8 0.51 10.3 3.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3797) zf-C3HC4_4 PF15227.6 EAQ92659.1 - 0.35 11.1 6.0 0.72 10.1 6.0 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 EAQ92659.1 - 0.63 9.9 9.9 11 6.0 10.8 2.1 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain DUF5401 PF17380.2 EAQ92659.1 - 0.95 7.5 13.6 1.3 7.0 13.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) DUF1682 PF07946.14 EAQ92659.1 - 3 7.0 8.2 4.4 6.4 8.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Rrn6 PF10214.9 EAQ92659.1 - 3.8 5.9 6.0 5.3 5.4 6.0 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor zf-RING_6 PF14835.6 EAQ92659.1 - 4.8 7.1 5.6 2.9 7.9 2.0 2.1 1 1 1 2 2 2 0 zf-RING of BARD1-type protein IBR PF01485.21 EAQ92659.1 - 8.5 6.7 8.0 9.3 6.6 2.9 2.3 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain ANTH PF07651.16 EAQ92660.1 - 4.3e-70 235.9 0.9 5.4e-70 235.5 0.9 1.1 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.20 EAQ92660.1 - 1.1e-06 28.7 0.0 2e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 ENTH domain tRNA-synt_2 PF00152.20 EAQ92661.1 - 1.1e-42 146.2 0.0 7.4e-37 127.1 0.0 2.6 2 1 0 2 2 2 2 tRNA synthetases class II (D, K and N) p450 PF00067.22 EAQ92663.1 - 4.7e-73 246.5 0.0 6e-73 246.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 TFIIS_M PF07500.14 EAQ92664.1 - 1.8e-24 86.4 0.1 1.8e-24 86.4 0.1 2.1 2 1 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 EAQ92664.1 - 2.5e-18 65.7 7.6 4.7e-18 64.8 7.6 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 EAQ92664.1 - 5e-12 45.7 0.7 1.6e-11 44.0 0.7 1.9 1 0 0 1 1 1 1 TFIIS helical bundle-like domain DpnD-PcfM PF14207.6 EAQ92664.1 - 0.076 12.9 0.4 0.21 11.5 0.4 1.7 1 0 0 1 1 1 0 DpnD/PcfM-like protein PALP PF00291.25 EAQ92665.1 - 1.2e-61 208.7 2.5 1.4e-61 208.5 2.5 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme tRNA-synt_1d PF00750.19 EAQ92665.1 - 0.22 10.4 0.0 0.31 9.9 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (R) Methyltransf_28 PF02636.17 EAQ92666.1 - 7.5e-32 111.0 0.0 1e-27 97.5 0.0 2.1 1 1 1 2 2 2 2 Putative S-adenosyl-L-methionine-dependent methyltransferase PRMT5 PF05185.16 EAQ92666.1 - 8.3e-05 22.5 0.0 0.00015 21.7 0.0 1.4 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase tRNA-synt_2c PF01411.19 EAQ92667.1 - 6.5e-160 533.3 0.7 1.9e-159 531.7 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 EAQ92667.1 - 3.2e-17 62.3 0.3 8.1e-17 61.0 0.3 1.8 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain GDE_C PF06202.14 EAQ92667.1 - 0.041 12.8 0.8 0.071 12.0 0.8 1.3 1 0 0 1 1 1 0 Amylo-alpha-1,6-glucosidase AviRa PF11599.8 EAQ92667.1 - 0.045 13.2 1.3 0.1 12.1 1.3 1.6 1 0 0 1 1 1 0 RRNA methyltransferase AviRa RCR PF12273.8 EAQ92669.1 - 3.7e-08 34.0 27.7 4.3e-07 30.6 27.7 2.4 1 1 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red PP2C PF00481.21 EAQ92670.1 - 1.8e-10 40.9 0.0 0.00027 20.7 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.12 EAQ92670.1 - 3e-10 40.3 0.1 2.7e-09 37.2 0.1 2.0 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 EAQ92670.1 - 3.6e-08 33.3 0.2 6.2e-08 32.5 0.2 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C GPI-anchored PF10342.9 EAQ92671.1 - 2.9e-15 56.8 0.6 2.9e-15 56.8 0.6 2.6 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family PARM PF17061.5 EAQ92671.1 - 0.029 14.5 23.6 0.035 14.3 23.6 1.1 1 0 0 1 1 1 0 PARM DUF2141 PF09912.9 EAQ92671.1 - 0.039 13.9 0.1 2.2 8.2 0.0 2.8 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2141) Plasmodium_Vir PF05795.11 EAQ92671.1 - 0.38 10.1 2.1 0.36 10.2 2.1 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Menin PF05053.13 EAQ92671.1 - 1.1 7.6 3.8 1.2 7.4 3.8 1.0 1 0 0 1 1 1 0 Menin Presenilin PF01080.17 EAQ92671.1 - 5.8 5.6 6.9 7.7 5.2 6.9 1.1 1 0 0 1 1 1 0 Presenilin Macoilin PF09726.9 EAQ92671.1 - 8 4.9 9.0 9.2 4.7 9.0 1.0 1 0 0 1 1 1 0 Macoilin family Apt1 PF10351.9 EAQ92671.1 - 10 4.9 10.7 12 4.6 10.7 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain NAD_binding_8 PF13450.6 EAQ92674.1 - 1.2e-10 41.4 0.1 4e-10 39.8 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.19 EAQ92674.1 - 5.8e-09 34.9 0.0 4.9e-08 31.8 0.0 2.2 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 EAQ92674.1 - 1.1e-05 24.8 0.0 0.035 13.3 0.1 3.8 3 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 EAQ92674.1 - 2.8e-05 23.5 0.0 0.033 13.4 0.0 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EAQ92674.1 - 6.2e-05 23.0 0.2 0.028 14.4 0.0 3.7 3 1 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.17 EAQ92674.1 - 0.17 11.1 0.1 0.71 9.1 0.0 1.9 2 0 0 2 2 2 0 Thi4 family Patatin PF01734.22 EAQ92675.1 - 9.5e-22 78.2 0.0 2.1e-21 77.0 0.0 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase TPR_12 PF13424.6 EAQ92675.1 - 1.2e-12 47.9 10.3 3.6e-05 24.0 0.4 4.8 6 0 0 6 6 6 3 Tetratricopeptide repeat AAA_16 PF13191.6 EAQ92675.1 - 5.4e-06 26.9 0.4 4e-05 24.1 0.0 2.6 4 0 0 4 4 4 1 AAA ATPase domain NB-ARC PF00931.22 EAQ92675.1 - 2.8e-05 23.4 0.0 5.9e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_3 PF07726.11 EAQ92675.1 - 0.21 11.5 0.0 0.39 10.6 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TPR_10 PF13374.6 EAQ92675.1 - 1.6 8.7 8.1 0.56 10.2 0.4 4.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.6 EAQ92676.1 - 7.8e-14 51.7 9.3 0.00019 21.6 0.2 5.5 4 1 1 5 5 5 5 Tetratricopeptide repeat Patatin PF01734.22 EAQ92676.1 - 1.5e-12 48.1 0.0 4.5e-12 46.6 0.0 1.8 1 0 0 1 1 1 1 Patatin-like phospholipase NB-ARC PF00931.22 EAQ92676.1 - 2.5e-11 43.2 0.0 6.4e-07 28.8 0.0 2.5 1 1 1 2 2 2 2 NB-ARC domain TPR_10 PF13374.6 EAQ92676.1 - 5.8e-06 26.0 16.0 0.39 10.6 0.3 6.2 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 EAQ92676.1 - 1.2e-05 25.0 17.2 0.65 10.3 0.2 6.7 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 EAQ92676.1 - 0.00016 21.3 9.2 0.95 9.4 0.0 5.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 EAQ92676.1 - 0.00035 21.1 12.5 2.2 9.3 0.0 6.3 5 1 1 6 6 5 1 Tetratricopeptide repeat AAA_16 PF13191.6 EAQ92676.1 - 0.00051 20.5 0.0 0.0022 18.4 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain TPR_MalT PF17874.1 EAQ92676.1 - 0.00069 19.1 3.9 0.067 12.6 0.1 2.6 2 0 0 2 2 2 2 MalT-like TPR region TPR_8 PF13181.6 EAQ92676.1 - 0.0025 17.9 11.9 1.1 9.6 0.1 6.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 EAQ92676.1 - 0.012 16.1 2.2 10 6.7 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 EAQ92676.1 - 0.013 16.1 2.5 8.6 7.3 0.1 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat SNARE PF05739.19 EAQ92676.1 - 0.066 13.2 0.9 0.55 10.3 0.6 2.5 2 0 0 2 2 2 0 SNARE domain TPR_6 PF13174.6 EAQ92676.1 - 0.87 10.4 4.3 15 6.4 0.2 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 EAQ92676.1 - 3.3 8.5 14.9 21 5.9 0.3 5.7 5 1 1 6 6 5 0 Tetratricopeptide repeat HA2 PF04408.23 EAQ92677.1 - 2e-19 69.9 0.0 2e-19 69.9 0.0 2.8 2 1 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EAQ92677.1 - 1.2e-13 51.3 0.0 3.3e-13 49.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 EAQ92677.1 - 9.3e-10 38.7 0.1 2.3e-09 37.5 0.1 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 EAQ92677.1 - 1.3e-05 25.1 0.0 4.6e-05 23.3 0.0 2.0 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAQ92677.1 - 1.3e-05 25.5 0.2 5.9e-05 23.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EAQ92677.1 - 0.095 12.6 0.2 0.28 11.1 0.0 1.8 2 0 0 2 2 2 0 RsgA GTPase ABC_tran PF00005.27 EAQ92677.1 - 0.096 13.2 0.0 0.096 13.2 0.0 2.8 2 1 0 2 2 2 0 ABC transporter AAA_29 PF13555.6 EAQ92677.1 - 0.15 11.8 0.0 0.39 10.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain GTP_EFTU PF00009.27 EAQ92678.1 - 3e-09 36.7 0.0 7.2e-09 35.5 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 EAQ92678.1 - 0.035 14.5 0.1 0.1 13.0 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 EAQ92678.1 - 0.062 13.1 0.4 0.16 11.7 0.4 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATP_bind_1 PF03029.17 EAQ92678.1 - 0.16 11.7 0.7 9 6.0 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein T2SSE PF00437.20 EAQ92678.1 - 0.16 11.0 0.0 0.28 10.2 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF5546 PF17700.1 EAQ92678.1 - 0.19 12.1 0.1 0.19 12.1 0.1 2.8 4 0 0 4 4 4 0 Family of unknown function (DUF5546) ABC_ATPase PF09818.9 EAQ92678.1 - 0.22 10.2 0.3 0.39 9.5 0.3 1.2 1 0 0 1 1 1 0 Predicted ATPase of the ABC class Rab5ip PF07019.12 EAQ92679.1 - 7.4e-28 97.0 5.0 9.7e-28 96.6 5.0 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) Vezatin PF12632.7 EAQ92680.1 - 3.1e-73 246.6 0.1 6e-73 245.6 0.1 1.5 1 0 0 1 1 1 1 Mysoin-binding motif of peroxisomes TBCC_N PF16752.5 EAQ92680.1 - 0.29 11.6 2.8 3.6 8.1 0.1 2.9 3 0 0 3 3 3 0 Tubulin-specific chaperone C N-terminal domain PCNA_N PF00705.18 EAQ92681.1 - 6.9e-58 193.9 4.6 4.3e-57 191.3 3.5 2.0 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 EAQ92681.1 - 4.7e-51 172.3 0.3 2.7e-50 169.8 0.1 1.9 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.13 EAQ92681.1 - 3.6e-08 33.2 0.1 4.5e-08 32.8 0.1 1.1 1 0 0 1 1 1 1 Rad9 Rad1 PF02144.16 EAQ92681.1 - 2.3e-05 23.6 2.1 0.00086 18.5 2.1 2.0 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Hus1 PF04005.12 EAQ92681.1 - 8.4e-05 21.8 0.2 0.0031 16.7 0.1 2.1 2 0 0 2 2 2 1 Hus1-like protein DNA_pol3_beta_3 PF02768.15 EAQ92681.1 - 0.027 14.3 0.3 0.21 11.4 0.0 2.3 2 1 1 3 3 3 0 DNA polymerase III beta subunit, C-terminal domain AMA-1 PF02430.15 EAQ92681.1 - 0.089 11.7 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Apical membrane antigen 1 Phos_pyr_kin PF08543.12 EAQ92682.1 - 0.0004 19.8 0.0 0.0013 18.2 0.0 1.7 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 EAQ92682.1 - 0.017 14.4 0.1 0.079 12.2 0.0 2.1 2 0 0 2 2 2 0 pfkB family carbohydrate kinase DUF1134 PF06577.12 EAQ92682.1 - 0.095 12.5 0.3 0.19 11.5 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1134) Latarcin PF10279.9 EAQ92682.1 - 0.099 13.1 0.1 0.19 12.1 0.1 1.4 1 0 0 1 1 1 0 Latarcin precursor IMS_HHH PF11798.8 EAQ92682.1 - 0.18 12.2 0.0 0.67 10.4 0.0 1.9 1 0 0 1 1 1 0 IMS family HHH motif dUTPase PF00692.19 EAQ92683.1 - 4.5e-42 142.8 0.0 5.4e-42 142.5 0.0 1.1 1 0 0 1 1 1 1 dUTPase CENP-K PF11802.8 EAQ92684.1 - 1.6e-16 60.7 0.1 4.9e-07 29.6 1.3 2.4 2 1 0 2 2 2 2 Centromere-associated protein K BST2 PF16716.5 EAQ92684.1 - 0.018 15.6 7.9 0.018 15.6 7.9 3.5 3 1 1 4 4 4 0 Bone marrow stromal antigen 2 Spc29 PF17082.5 EAQ92684.1 - 0.04 13.7 3.1 0.3 10.9 1.5 2.3 2 0 0 2 2 2 0 Spindle Pole Component 29 MID_MedPIWI PF18296.1 EAQ92684.1 - 0.098 12.4 0.1 0.21 11.4 0.0 1.5 1 1 1 2 2 2 0 MID domain of medPIWI TMPIT PF07851.13 EAQ92684.1 - 0.54 9.4 3.6 5 6.3 4.1 2.0 2 0 0 2 2 2 0 TMPIT-like protein Fez1 PF06818.15 EAQ92684.1 - 1 9.8 15.7 1.3 9.5 7.4 2.9 3 0 0 3 3 3 0 Fez1 DDHD PF02862.17 EAQ92684.1 - 2.9 8.0 4.3 9.3 6.3 0.1 2.5 1 1 1 2 2 2 0 DDHD domain DUF1664 PF07889.12 EAQ92684.1 - 3.1 7.9 7.2 6.9 6.7 3.4 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) HAUS6_N PF14661.6 EAQ92684.1 - 5.3 6.5 10.6 0.056 13.0 1.1 2.3 3 0 0 3 3 3 0 HAUS augmin-like complex subunit 6 N-terminus Atg14 PF10186.9 EAQ92684.1 - 5.8 5.9 21.5 0.29 10.2 10.9 2.7 3 0 0 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 Spc7 PF08317.11 EAQ92684.1 - 6.9 5.4 24.6 0.095 11.6 12.5 2.5 2 1 1 3 3 3 0 Spc7 kinetochore protein KH_1 PF00013.29 EAQ92685.1 - 8.8e-44 147.2 7.7 3.2e-18 65.3 0.7 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 EAQ92685.1 - 4.3e-13 48.9 5.0 0.0046 16.7 0.1 3.2 3 0 0 3 3 3 3 KH domain MOEP19 PF16005.5 EAQ92685.1 - 1e-05 25.4 0.0 0.0099 15.9 0.0 3.2 3 0 0 3 3 3 1 KH-like RNA-binding domain KH_4 PF13083.6 EAQ92685.1 - 1.6e-05 24.7 2.6 0.34 10.8 0.2 3.4 3 0 0 3 3 3 2 KH domain KH_5 PF13184.6 EAQ92685.1 - 0.00038 20.5 9.0 0.34 11.0 0.3 3.4 3 0 0 3 3 3 3 NusA-like KH domain RVT_1 PF00078.27 EAQ92686.1 - 6e-19 68.4 0.0 1e-18 67.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_C12 PF01088.21 EAQ92687.1 - 3.5e-30 105.3 0.0 1.7e-27 96.6 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 DUF2443 PF10398.9 EAQ92688.1 - 0.12 12.5 0.1 0.2 11.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2443) Baculo_PEP_C PF04513.12 EAQ92688.1 - 0.14 12.2 2.1 0.22 11.6 0.1 2.2 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3169 PF11368.8 EAQ92688.1 - 3.1 7.3 5.8 6.3 6.2 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) DUF1765 PF08578.10 EAQ92689.1 - 2.4e-47 160.5 0.8 3.8e-47 159.8 0.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) Cys_Met_Meta_PP PF01053.20 EAQ92690.1 - 2.6e-139 464.0 0.3 3e-139 463.8 0.3 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 EAQ92690.1 - 4.8e-07 29.3 0.2 7.5e-07 28.6 0.2 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EAQ92690.1 - 9e-07 28.2 1.6 1.2e-06 27.8 0.7 1.6 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 EAQ92690.1 - 3.5e-06 26.6 0.6 6.7e-06 25.7 0.6 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 EAQ92690.1 - 0.0011 18.3 0.5 0.0025 17.2 0.5 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase GDC-P PF02347.16 EAQ92690.1 - 0.01 14.7 0.2 0.01 14.7 0.2 1.4 2 0 0 2 2 2 0 Glycine cleavage system P-protein Big_3_5 PF16640.5 EAQ92690.1 - 2.6 8.3 8.0 4.2 7.6 4.3 2.5 2 1 0 2 2 2 0 Bacterial Ig-like domain (group 3) Fungal_trans_2 PF11951.8 EAQ92691.1 - 0.00081 18.3 0.4 0.0017 17.2 0.4 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EAQ92691.1 - 0.0049 17.0 1.6 0.0093 16.1 1.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GlcNAc_2-epim PF07221.11 EAQ92691.1 - 0.019 14.2 0.6 0.72 9.0 0.3 2.3 2 0 0 2 2 2 0 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) Brix PF04427.18 EAQ92692.1 - 1.9e-42 145.5 0.0 2.5e-42 145.2 0.0 1.1 1 0 0 1 1 1 1 Brix domain zf-MYND PF01753.18 EAQ92693.1 - 5.1e-08 32.9 10.6 9.9e-08 32.0 10.6 1.5 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.16 EAQ92693.1 - 0.013 15.4 11.8 0.023 14.5 11.8 1.5 1 0 0 1 1 1 0 HIT zinc finger MFS_1 PF07690.16 EAQ92694.1 - 1.8e-16 60.0 10.0 2.3e-16 59.7 10.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1275 PF06912.11 EAQ92695.1 - 2e-45 155.1 17.5 2.5e-45 154.8 17.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) Ribosomal_L34 PF00468.17 EAQ92695.1 - 0.72 9.9 3.6 5.5 7.0 0.0 3.0 3 0 0 3 3 3 0 Ribosomal protein L34 UPF0154 PF03672.13 EAQ92695.1 - 3.3 7.8 4.3 13 5.9 0.2 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) DUF4131 PF13567.6 EAQ92695.1 - 7.7 6.1 16.4 6.9 6.3 4.9 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Helicase_C PF00271.31 EAQ92696.1 - 3.3e-17 62.8 0.0 1.8e-16 60.5 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 EAQ92696.1 - 7.3e-17 61.9 4.1 1.7e-16 60.7 4.1 1.7 1 0 0 1 1 1 1 RecQ zinc-binding RQC PF09382.10 EAQ92696.1 - 1.9e-11 43.8 0.0 3.4e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 RQC domain DEAD PF00270.29 EAQ92696.1 - 0.00072 19.4 0.2 0.0018 18.1 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase KAR9 PF08580.10 EAQ92698.1 - 1.3e-184 615.6 10.0 1.3e-184 615.6 10.0 3.1 2 2 0 2 2 2 1 Yeast cortical protein KAR9 Syntaxin-6_N PF09177.11 EAQ92698.1 - 0.018 15.6 6.0 0.88 10.2 0.0 3.9 2 1 0 2 2 2 0 Syntaxin 6, N-terminal DUF4618 PF15397.6 EAQ92698.1 - 7.9 5.8 5.9 10 5.4 0.6 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4618) Ank_2 PF12796.7 EAQ92699.1 - 1.7e-39 134.3 8.9 1.7e-15 57.3 0.0 8.5 6 2 2 8 8 8 6 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAQ92699.1 - 2.8e-29 97.9 7.3 0.0037 17.6 0.0 12.3 13 1 0 13 13 13 6 Ankyrin repeat Ank_4 PF13637.6 EAQ92699.1 - 6.7e-24 83.9 5.6 3.7e-09 36.9 0.1 10.5 10 3 3 13 13 13 5 Ankyrin repeats (many copies) Ank PF00023.30 EAQ92699.1 - 6.8e-22 76.9 18.2 0.00085 19.7 0.0 10.6 10 1 0 10 10 10 6 Ankyrin repeat Ank_5 PF13857.6 EAQ92699.1 - 1.3e-21 76.4 10.1 0.0037 17.5 0.2 10.4 9 2 2 11 11 11 5 Ankyrin repeats (many copies) Sod_Cu PF00080.20 EAQ92701.1 - 1.9e-09 37.8 0.0 2.4e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) CHRD PF07452.12 EAQ92701.1 - 0.015 16.3 0.1 0.019 16.0 0.0 1.3 1 1 0 1 1 1 0 CHRD domain Aminotran_5 PF00266.19 EAQ92702.1 - 7.7e-05 21.8 0.0 0.00018 20.6 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class-V DUF202 PF02656.15 EAQ92707.1 - 3.7e-05 24.1 0.7 6.5e-05 23.3 0.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF202) GRA6 PF05084.13 EAQ92710.1 - 0.039 13.9 8.6 0.058 13.3 8.6 1.2 1 0 0 1 1 1 0 Granule antigen protein (GRA6) SOG2 PF10428.9 EAQ92710.1 - 0.17 11.1 10.6 0.23 10.6 6.9 2.0 2 0 0 2 2 2 0 RAM signalling pathway protein NUDE_C PF04880.13 EAQ92710.1 - 0.27 11.7 5.0 0.16 12.5 3.1 1.7 2 0 0 2 2 2 0 NUDE protein, C-terminal conserved region DUF3275 PF11679.8 EAQ92710.1 - 2.3 8.2 6.7 0.088 12.8 0.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3275) Med3 PF11593.8 EAQ92710.1 - 9.8 5.2 22.1 18 4.4 22.1 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DAD PF02109.16 EAQ92711.1 - 1.2e-49 167.2 0.7 1.5e-49 166.9 0.7 1.1 1 0 0 1 1 1 1 DAD family DUF3439 PF11921.8 EAQ92711.1 - 2.6 8.1 10.9 5.6 7.0 10.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) TMEM119 PF15724.5 EAQ92711.1 - 7.8 6.5 9.0 14 5.6 9.0 1.4 1 0 0 1 1 1 0 TMEM119 family GRASP55_65 PF04495.14 EAQ92712.1 - 4.1e-48 163.2 0.0 7.1e-47 159.2 0.0 2.1 1 1 1 2 2 2 1 GRASP55/65 PDZ-like domain PDZ_6 PF17820.1 EAQ92712.1 - 0.0062 16.4 0.4 3.4 7.6 0.0 2.6 3 0 0 3 3 3 2 PDZ domain Methyltransf_15 PF09445.10 EAQ92713.1 - 1.5e-49 167.8 0.0 2.4e-49 167.1 0.0 1.3 1 1 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Met_10 PF02475.16 EAQ92713.1 - 6.8e-05 22.7 0.0 7.6e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Cons_hypoth95 PF03602.15 EAQ92713.1 - 0.00082 19.1 0.0 0.0026 17.4 0.0 1.7 2 0 0 2 2 2 1 Conserved hypothetical protein 95 UPF0020 PF01170.18 EAQ92713.1 - 0.0013 18.4 0.0 0.0078 15.9 0.0 2.0 2 0 0 2 2 2 1 Putative RNA methylase family UPF0020 Methyltransf_25 PF13649.6 EAQ92713.1 - 0.0015 19.1 0.1 0.0034 18.1 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain N6_N4_Mtase PF01555.18 EAQ92713.1 - 0.034 13.9 0.0 0.09 12.5 0.0 1.7 2 0 0 2 2 2 0 DNA methylase Methyltransf_5 PF01795.19 EAQ92713.1 - 0.045 13.2 0.0 0.056 12.9 0.0 1.1 1 0 0 1 1 1 0 MraW methylase family MTS PF05175.14 EAQ92713.1 - 0.051 13.1 0.0 0.075 12.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_18 PF12847.7 EAQ92713.1 - 0.092 12.7 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 EAQ92713.1 - 0.15 12.7 0.0 0.31 11.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Dopey_N PF04118.14 EAQ92714.1 - 4.6e-116 387.2 0.0 2.1e-115 385.1 0.0 2.0 2 0 0 2 2 2 1 Dopey, N-terminal BEN PF10523.9 EAQ92714.1 - 0.042 14.1 0.0 0.23 11.7 0.0 2.2 2 0 0 2 2 2 0 BEN domain Mon1 PF03164.14 EAQ92715.1 - 3.3e-151 503.9 0.0 4e-151 503.7 0.0 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 Thioredoxin PF00085.20 EAQ92717.1 - 2.1e-62 207.6 4.6 1.2e-31 108.7 0.4 3.7 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.6 EAQ92717.1 - 1.1e-47 162.4 2.5 3.8e-35 121.5 0.4 3.4 2 2 2 4 4 4 3 Thioredoxin-like domain Calsequestrin PF01216.17 EAQ92717.1 - 2.4e-09 36.7 1.9 4.9e-09 35.7 1.9 1.4 1 0 0 1 1 1 1 Calsequestrin Redoxin PF08534.10 EAQ92717.1 - 5.1e-09 36.0 3.8 0.0016 18.1 0.0 3.4 2 1 0 3 3 3 3 Redoxin Thioredoxin_8 PF13905.6 EAQ92717.1 - 5.9e-09 36.1 0.0 0.0027 18.0 0.0 3.7 3 0 0 3 3 3 2 Thioredoxin-like OST3_OST6 PF04756.13 EAQ92717.1 - 7.9e-08 32.0 1.5 0.0098 15.3 0.0 2.9 3 0 0 3 3 3 2 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 EAQ92717.1 - 1.1e-07 31.7 1.8 0.0054 16.7 0.1 3.4 3 0 0 3 3 3 2 AhpC/TSA family Thioredoxin_2 PF13098.6 EAQ92717.1 - 1.3e-07 32.0 1.0 0.0049 17.3 0.1 3.3 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 EAQ92717.1 - 1.7e-07 31.3 0.2 0.026 14.7 0.0 3.2 3 0 0 3 3 3 2 Thioredoxin-like ERp29_N PF07912.13 EAQ92717.1 - 3.2e-05 24.1 3.0 1.5 8.9 0.1 4.3 3 2 0 3 3 3 2 ERp29, N-terminal domain DSBA PF01323.20 EAQ92717.1 - 0.003 17.4 0.4 0.19 11.5 0.1 2.7 2 1 0 2 2 2 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 EAQ92717.1 - 0.65 10.1 7.1 3.6 7.7 0.5 3.6 3 2 0 3 3 3 0 Thioredoxin zf-HIT PF04438.16 EAQ92718.1 - 4.8e-09 35.9 5.3 4.8e-09 35.9 5.3 1.6 2 0 0 2 2 2 1 HIT zinc finger SR-25 PF10500.9 EAQ92718.1 - 0.0035 17.0 6.6 0.0062 16.2 6.6 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Trypan_PARP PF05887.11 EAQ92718.1 - 0.0055 16.7 16.3 0.013 15.5 16.3 1.6 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) AP3D1 PF06375.11 EAQ92718.1 - 0.048 13.9 8.1 0.086 13.1 8.1 1.3 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 Eapp_C PF10238.9 EAQ92718.1 - 0.18 11.9 1.9 0.61 10.2 1.9 1.8 1 1 0 1 1 1 0 E2F-associated phosphoprotein TFIIA PF03153.13 EAQ92718.1 - 3.1 7.7 12.8 4.7 7.1 12.8 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spem1 PF15670.5 EAQ92718.1 - 3.1 7.3 6.1 3.4 7.2 1.7 2.6 1 1 1 2 2 2 0 Spermatid maturation protein 1 Macoilin PF09726.9 EAQ92718.1 - 7.7 4.9 6.6 10 4.6 6.6 1.1 1 0 0 1 1 1 0 Macoilin family DUF3090 PF11290.8 EAQ92719.1 - 0.08 12.7 1.2 0.2 11.5 0.4 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3090) WLM PF08325.10 EAQ92720.1 - 9.5e-28 97.6 0.1 2e-27 96.5 0.1 1.6 1 1 0 1 1 1 1 WLM domain DUF45 PF01863.17 EAQ92720.1 - 6.7e-08 32.8 0.4 1.6e-07 31.6 0.4 1.5 1 0 0 1 1 1 1 Protein of unknown function DUF45 zf-RanBP PF00641.18 EAQ92720.1 - 0.0024 17.1 6.4 0.0078 15.5 6.4 1.9 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others DUF4110 PF13422.6 EAQ92721.1 - 1.1e-31 108.8 0.3 1.1e-31 108.8 0.3 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF4110) Kelch_3 PF13415.6 EAQ92721.1 - 2.1e-22 78.9 14.0 9e-08 32.2 0.1 6.4 7 0 0 7 7 7 3 Galactose oxidase, central domain Kelch_4 PF13418.6 EAQ92721.1 - 2.7e-22 78.5 19.1 9.9e-06 25.5 0.0 6.7 6 2 1 7 7 7 5 Galactose oxidase, central domain Kelch_5 PF13854.6 EAQ92721.1 - 1.3e-17 63.4 2.7 4.2e-07 29.8 0.0 5.9 6 0 0 6 6 6 3 Kelch motif Kelch_2 PF07646.15 EAQ92721.1 - 4.2e-16 58.2 2.0 0.0025 17.7 0.0 6.0 5 1 0 5 5 5 4 Kelch motif Kelch_1 PF01344.25 EAQ92721.1 - 2.9e-15 55.6 3.8 1.8e-05 24.2 0.0 5.0 4 1 0 4 4 4 4 Kelch motif Kelch_6 PF13964.6 EAQ92721.1 - 6.2e-14 51.7 3.0 0.00051 20.2 0.1 5.7 6 0 0 6 6 6 2 Kelch motif BUD22 PF09073.10 EAQ92721.1 - 0.79 9.0 31.6 0.027 13.8 14.0 2.5 2 0 0 2 2 2 0 BUD22 SelK_SelG PF10961.8 EAQ92721.1 - 0.99 10.1 13.0 8.7 7.0 6.2 2.7 2 0 0 2 2 2 0 Selenoprotein SelK_SelG PI3K_1B_p101 PF10486.9 EAQ92721.1 - 9.6 3.8 6.4 17 3.0 6.4 1.3 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit ERAP1_C PF11838.8 EAQ92722.1 - 3.7e-88 296.1 0.1 1.6e-87 294.0 0.1 2.1 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 EAQ92722.1 - 1.4e-85 286.3 0.6 2.2e-85 285.7 0.6 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 EAQ92722.1 - 2e-50 171.6 0.9 4.3e-50 170.5 0.3 1.8 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain Enolase_C PF00113.22 EAQ92723.1 - 1.2e-152 507.3 0.1 1.6e-152 506.9 0.1 1.2 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 EAQ92723.1 - 2.8e-43 147.2 0.8 3.9e-35 120.9 0.2 2.8 2 1 1 3 3 3 2 Enolase, N-terminal domain MR_MLE_C PF13378.6 EAQ92723.1 - 1.2e-07 31.5 0.0 2.8e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 EAQ92723.1 - 0.00019 20.6 0.8 0.05 12.7 0.1 3.0 3 0 0 3 3 3 1 Methylaspartate ammonia-lyase C-terminus Mad3_BUB1_I PF08311.12 EAQ92724.1 - 1.3e-43 147.9 0.4 4.3e-43 146.2 0.4 2.0 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Pkinase PF00069.25 EAQ92724.1 - 5.4e-07 29.2 0.0 2.1e-06 27.3 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Mad3_BUB1_II PF08171.11 EAQ92724.1 - 3e-06 27.3 0.0 2e-05 24.6 0.0 2.4 3 0 0 3 3 3 1 Mad3/BUB1 homology region 2 Pkinase_Tyr PF07714.17 EAQ92724.1 - 0.0044 16.4 0.0 0.023 14.0 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase AP_endonuc_2 PF01261.24 EAQ92725.1 - 1.4e-31 109.6 0.5 2.8e-31 108.6 0.2 1.6 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel F-box-like PF12937.7 EAQ92726.1 - 3.8e-05 23.5 0.0 8.8e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 F-box-like DUF2415 PF10313.9 EAQ92726.1 - 0.055 13.4 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein domain (DUF2415) F-box_4 PF15966.5 EAQ92726.1 - 0.17 11.8 0.0 0.49 10.3 0.0 1.8 1 1 1 2 2 2 0 F-box RRM_1 PF00076.22 EAQ92727.1 - 6e-12 45.2 0.0 1e-11 44.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 EAQ92727.1 - 0.00019 21.9 28.6 0.00019 21.9 28.6 3.5 3 1 0 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 Btz PF09405.10 EAQ92727.1 - 0.018 15.3 0.0 0.046 14.0 0.0 1.7 1 0 0 1 1 1 0 CASC3/Barentsz eIF4AIII binding Nup35_RRM_2 PF14605.6 EAQ92727.1 - 0.11 12.5 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif DEAD PF00270.29 EAQ92728.1 - 8.3e-46 155.9 1.5 1.4e-45 155.2 1.5 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EAQ92728.1 - 4e-32 110.8 0.3 6.4e-31 107.0 0.1 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EAQ92728.1 - 7.1e-06 26.1 0.0 1.1e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 EAQ92728.1 - 0.00057 19.7 0.1 0.0012 18.6 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAQ92728.1 - 0.00099 19.5 1.4 0.0078 16.6 0.5 2.3 2 1 0 2 2 2 1 AAA domain CMS1 PF14617.6 EAQ92728.1 - 0.012 15.0 0.3 0.026 13.9 0.0 1.7 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit AAA_22 PF13401.6 EAQ92728.1 - 0.016 15.4 0.8 0.084 13.1 0.8 2.2 1 1 0 1 1 1 0 AAA domain IL17R_D_N PF16742.5 EAQ92728.1 - 0.065 13.3 0.0 0.17 11.9 0.0 1.7 1 0 0 1 1 1 0 N-terminus of interleukin 17 receptor D tRNA-synt_1b PF00579.25 EAQ92728.1 - 0.089 12.1 0.0 0.49 9.7 0.0 2.1 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) Helicase_RecD PF05127.14 EAQ92728.1 - 0.089 12.6 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 Helicase Flavi_DEAD PF07652.14 EAQ92728.1 - 0.097 12.6 0.2 0.64 10.0 0.2 2.2 1 1 0 1 1 1 0 Flavivirus DEAD domain fragilysinNterm PF16376.5 EAQ92728.1 - 0.11 12.2 0.0 0.32 10.7 0.0 1.7 1 0 0 1 1 1 0 N-terminal domain of fragilysin Cupin_8 PF13621.6 EAQ92729.1 - 1.8e-17 63.9 0.1 4.4e-16 59.4 0.1 2.1 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 EAQ92729.1 - 2.9e-10 40.6 0.0 7e-10 39.3 0.0 1.7 1 1 0 1 1 1 1 JmjC domain, hydroxylase F-box-like PF12937.7 EAQ92729.1 - 0.0027 17.5 0.2 0.0066 16.3 0.0 1.7 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EAQ92729.1 - 0.04 13.8 0.0 0.096 12.6 0.0 1.5 1 0 0 1 1 1 0 F-box domain Cupin_4 PF08007.12 EAQ92729.1 - 0.086 12.3 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Cupin superfamily protein F-box_4 PF15966.5 EAQ92729.1 - 0.23 11.3 1.8 0.24 11.3 0.0 1.8 2 0 0 2 2 2 0 F-box DUF1771 PF08590.10 EAQ92730.1 - 2.2e-15 56.8 11.7 6.5e-15 55.3 11.7 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.21 EAQ92730.1 - 1e-06 29.0 0.0 3.4e-06 27.3 0.0 1.9 1 0 0 1 1 1 1 Smr domain zf-CCCH PF00642.24 EAQ92730.1 - 0.0019 18.1 0.2 0.004 17.0 0.2 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) HBS1_N PF08938.10 EAQ92730.1 - 0.009 16.3 0.0 0.02 15.2 0.0 1.6 1 0 0 1 1 1 1 HBS1 N-terminus PAM2 PF07145.15 EAQ92730.1 - 0.018 14.7 0.0 0.049 13.3 0.0 1.8 1 0 0 1 1 1 0 Ataxin-2 C-terminal region zf-CCCH_2 PF14608.6 EAQ92730.1 - 0.089 13.3 0.5 0.16 12.5 0.5 1.4 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger zf_CCCH_4 PF18345.1 EAQ92730.1 - 0.14 12.2 1.5 0.59 10.3 1.5 2.0 1 1 0 1 1 1 0 Zinc finger domain zf-CCCH_4 PF18044.1 EAQ92730.1 - 3.4 7.6 4.5 33 4.4 4.5 2.3 1 1 0 1 1 1 0 CCCH-type zinc finger SNARE_assoc PF09335.11 EAQ92731.1 - 3.1e-12 47.0 9.1 3.1e-12 47.0 9.1 2.6 3 1 1 4 4 4 1 SNARE associated Golgi protein DUF3487 PF11990.8 EAQ92731.1 - 1.1 9.2 4.7 0.87 9.5 1.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3487) Abhydrolase_1 PF00561.20 EAQ92733.1 - 1.2e-10 41.5 0.0 3.3e-10 40.0 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EAQ92733.1 - 3.7e-09 36.2 0.0 8.1e-09 35.1 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EAQ92733.1 - 3e-05 24.8 3.8 0.0072 16.9 3.8 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S28 PF05577.12 EAQ92733.1 - 0.00035 19.5 0.0 0.00052 18.9 0.0 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Esterase PF00756.20 EAQ92733.1 - 0.0014 18.3 0.0 0.0034 17.1 0.0 1.6 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 EAQ92733.1 - 0.026 14.0 0.1 0.27 10.7 0.1 2.1 1 1 0 1 1 1 0 Prolyl oligopeptidase family BTB PF00651.31 EAQ92734.1 - 8e-08 32.5 0.0 1.1e-07 32.0 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain DEAD PF00270.29 EAQ92735.1 - 4.1e-16 59.2 0.0 1.8e-15 57.2 0.0 2.1 3 0 0 3 3 3 1 DEAD/DEAH box helicase ResIII PF04851.15 EAQ92735.1 - 0.00072 19.6 0.0 0.0015 18.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HHH_5 PF14520.6 EAQ92735.1 - 0.061 13.9 0.0 0.22 12.2 0.0 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix domain BAH PF01426.18 EAQ92737.1 - 3.4e-16 59.2 0.0 7.5e-16 58.1 0.0 1.6 1 0 0 1 1 1 1 BAH domain zf-HC5HC2H_2 PF13832.6 EAQ92737.1 - 9.8e-11 41.8 0.3 9.8e-11 41.8 0.3 3.9 3 1 1 4 4 4 1 PHD-zinc-finger like domain PHD_2 PF13831.6 EAQ92737.1 - 6.9e-09 35.1 4.8 6.9e-09 35.1 4.8 3.7 4 0 0 4 4 4 1 PHD-finger PHD PF00628.29 EAQ92737.1 - 4e-06 26.6 7.0 4e-06 26.6 7.0 5.1 6 0 0 6 6 6 1 PHD-finger zf-HC5HC2H PF13771.6 EAQ92737.1 - 0.00037 20.7 0.4 0.00037 20.7 0.4 4.3 3 1 0 3 3 3 1 PHD-like zinc-binding domain C1_1 PF00130.22 EAQ92737.1 - 0.0012 18.6 1.9 0.0012 18.6 1.9 4.4 5 1 1 6 6 6 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Myb_DNA-binding PF00249.31 EAQ92737.1 - 0.0026 17.9 1.0 0.0085 16.3 0.0 2.4 2 0 0 2 2 2 1 Myb-like DNA-binding domain C1_2 PF03107.16 EAQ92737.1 - 0.0093 16.3 0.4 0.0093 16.3 0.4 4.7 5 0 0 5 5 5 2 C1 domain GATA PF00320.27 EAQ92737.1 - 1.3 8.7 7.2 1.1 8.9 0.6 3.6 3 0 0 3 3 3 0 GATA zinc finger DUF1178 PF06676.11 EAQ92737.1 - 3.3 8.1 15.1 3.5 8.0 0.4 3.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1178) DnaJ_C PF01556.18 EAQ92739.1 - 1.6e-37 128.9 0.0 2e-37 128.5 0.0 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EAQ92739.1 - 1.6e-27 95.4 1.7 2.9e-27 94.6 1.7 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EAQ92739.1 - 2.4e-15 56.6 17.2 4.3e-15 55.8 17.2 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.19 EAQ92739.1 - 1.4 8.9 9.5 2.2 8.3 1.9 2.4 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Anti-TRAP PF15777.5 EAQ92739.1 - 1.6 8.7 15.9 2.6 8.1 1.8 2.6 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein zinc-ribbons_6 PF07191.12 EAQ92739.1 - 2.5 8.1 7.7 1.3 9.1 1.7 2.4 1 1 1 2 2 2 0 zinc-ribbons DUF2614 PF11023.8 EAQ92739.1 - 4.4 7.4 6.2 22 5.2 0.4 2.2 1 1 1 2 2 2 0 Zinc-ribbon containing domain WD40 PF00400.32 EAQ92740.1 - 0.18 12.7 0.1 0.88 10.5 0.1 2.2 2 0 0 2 2 2 0 WD domain, G-beta repeat Ribosomal_L10 PF00466.20 EAQ92741.1 - 5.4e-23 81.0 0.1 1.4e-22 79.7 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein L10 RL10P_insert PF17777.1 EAQ92741.1 - 9e-23 80.1 0.0 1.7e-22 79.2 0.0 1.5 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_60s PF00428.19 EAQ92741.1 - 1.4e-15 57.7 3.2 1.4e-15 57.7 3.2 2.3 3 0 0 3 3 3 1 60s Acidic ribosomal protein MutS_V PF00488.21 EAQ92742.1 - 8.2e-70 234.7 0.0 1.4e-69 233.9 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EAQ92742.1 - 8.7e-20 71.8 0.0 2.1e-17 64.0 0.0 2.4 1 1 0 1 1 1 1 MutS domain III MutS_I PF01624.20 EAQ92742.1 - 2.7e-18 66.3 0.0 1e-17 64.4 0.0 2.0 2 0 0 2 2 2 1 MutS domain I AAA_29 PF13555.6 EAQ92742.1 - 0.0081 15.9 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 EAQ92742.1 - 0.056 13.7 0.0 1.7 8.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 EAQ92742.1 - 0.16 12.5 0.2 0.56 10.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain Nop14 PF04147.12 EAQ92743.1 - 0.22 9.7 13.9 0.31 9.2 13.9 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 EAQ92743.1 - 0.39 10.1 15.0 0.68 9.3 15.0 1.3 1 0 0 1 1 1 0 SDA1 YL1 PF05764.13 EAQ92743.1 - 2.4 8.2 16.8 0.64 10.1 12.0 2.1 2 0 0 2 2 2 0 YL1 nuclear protein FA_desaturase PF00487.24 EAQ92743.1 - 3.3 7.5 14.2 9.7 5.9 14.2 1.6 1 1 0 1 1 1 0 Fatty acid desaturase Glyco_hydro_38N PF01074.22 EAQ92744.1 - 1.9e-87 293.3 0.1 3.8e-87 292.3 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 EAQ92744.1 - 3.5e-50 171.0 0.9 1.2e-49 169.3 0.5 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 EAQ92744.1 - 1.3e-28 99.0 0.0 3.3e-28 97.7 0.0 1.8 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 EAQ92744.1 - 1.4e-09 37.9 0.0 5.2e-09 36.1 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain 7TMR-DISMED2 PF07696.11 EAQ92744.1 - 0.16 12.1 1.1 0.45 10.6 0.1 2.3 2 1 0 2 2 2 0 7TMR-DISM extracellular 2 Nop14 PF04147.12 EAQ92745.1 - 1.7e-301 1002.7 28.2 2.1e-301 1002.3 28.2 1.1 1 0 0 1 1 1 1 Nop14-like family P22_portal PF16510.5 EAQ92746.1 - 0.092 11.3 0.0 0.15 10.6 0.0 1.3 1 0 0 1 1 1 0 Phage P22-like portal protein CAP_GLY PF01302.25 EAQ92747.1 - 3.3e-16 59.0 0.2 8e-16 57.8 0.2 1.7 1 0 0 1 1 1 1 CAP-Gly domain CLIP1_ZNF PF16641.5 EAQ92747.1 - 2e-06 27.5 10.2 0.00047 20.0 1.3 2.5 2 0 0 2 2 2 2 CLIP1 zinc knuckle Spc7 PF08317.11 EAQ92747.1 - 0.019 13.8 30.4 0.12 11.3 5.7 3.3 2 1 2 4 4 4 0 Spc7 kinetochore protein Glutaredoxin2_C PF04399.13 EAQ92747.1 - 0.026 14.4 5.1 0.47 10.3 0.4 2.5 2 0 0 2 2 2 0 Glutaredoxin 2, C terminal domain DUF812 PF05667.11 EAQ92747.1 - 0.034 13.0 31.4 0.035 13.0 18.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF812) BLOC1_2 PF10046.9 EAQ92747.1 - 0.09 13.1 14.8 0.03 14.6 2.0 3.5 4 0 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Med4 PF10018.9 EAQ92747.1 - 0.13 11.9 15.8 0.065 12.9 0.7 3.0 3 0 0 3 3 2 0 Vitamin-D-receptor interacting Mediator subunit 4 DivIC PF04977.15 EAQ92747.1 - 0.24 11.2 22.7 0.25 11.1 0.4 5.0 4 1 1 5 5 5 0 Septum formation initiator NPV_P10 PF05531.12 EAQ92747.1 - 0.44 11.0 13.3 2.5 8.6 2.8 3.1 3 1 1 4 4 3 0 Nucleopolyhedrovirus P10 protein zf_PR_Knuckle PF18445.1 EAQ92747.1 - 0.58 10.0 3.3 7.4 6.5 0.2 2.5 2 0 0 2 2 2 0 PR zinc knuckle motif SesA PF17107.5 EAQ92747.1 - 0.61 10.3 8.3 1.1 9.5 2.9 3.1 1 1 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Pkip-1 PF06878.11 EAQ92747.1 - 0.89 9.6 10.4 0.75 9.9 2.0 2.3 1 1 1 2 2 2 0 Pkip-1 protein AAA_13 PF13166.6 EAQ92747.1 - 1.1 7.8 21.2 0.011 14.5 7.1 2.5 1 1 2 3 3 3 0 AAA domain Cauli_AT PF03233.13 EAQ92747.1 - 2.3 8.1 5.1 1.7 8.5 0.9 2.4 2 0 0 2 2 2 0 Aphid transmission protein HrpB7 PF09486.10 EAQ92747.1 - 2.7 8.4 34.7 3.6 7.9 16.0 3.5 2 1 1 3 3 3 0 Bacterial type III secretion protein (HrpB7) FliD_N PF02465.18 EAQ92747.1 - 2.9 8.7 10.7 7.5 7.3 1.2 3.2 2 1 1 3 3 2 0 Flagellar hook-associated protein 2 N-terminus DP PF08781.10 EAQ92747.1 - 3.1 7.7 11.3 0.35 10.7 3.2 2.6 2 0 0 2 2 2 0 Transcription factor DP FAM76 PF16046.5 EAQ92747.1 - 3.3 7.0 20.9 0.25 10.7 2.7 3.2 2 1 1 3 3 3 0 FAM76 protein Fib_alpha PF08702.10 EAQ92747.1 - 3.7 7.7 20.4 1.2 9.3 1.8 3.5 1 1 5 6 6 6 0 Fibrinogen alpha/beta chain family Sec8_exocyst PF04048.14 EAQ92747.1 - 3.7 7.4 6.2 11 5.9 1.0 2.6 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain Phage_GP20 PF06810.11 EAQ92747.1 - 3.8 7.3 20.6 1.4 8.7 5.2 3.2 1 1 1 2 2 2 0 Phage minor structural protein GP20 DUF948 PF06103.11 EAQ92747.1 - 4.3 7.7 6.1 0.85 9.9 0.6 2.6 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF745 PF05335.13 EAQ92747.1 - 4.3 7.0 21.7 2 8.1 4.9 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF745) T2SSM PF04612.12 EAQ92747.1 - 6 6.9 10.1 1.4 8.9 0.9 2.6 2 1 0 2 2 2 0 Type II secretion system (T2SS), protein M NuDC PF16273.5 EAQ92747.1 - 8.7 7.0 10.4 12 6.5 3.0 3.0 2 0 0 2 2 2 0 Nuclear distribution C domain Pkinase PF00069.25 EAQ92748.1 - 1.2e-24 87.1 0.0 2.3e-14 53.4 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ92748.1 - 3.8e-09 36.2 0.0 9.8e-05 21.8 0.0 3.0 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EAQ92748.1 - 0.0029 17.0 0.0 1 8.6 0.0 2.1 2 0 0 2 2 2 2 Kinase-like IU_nuc_hydro PF01156.19 EAQ92749.1 - 3.9e-13 49.6 0.2 9.4e-06 25.4 0.1 2.6 2 1 1 3 3 3 2 Inosine-uridine preferring nucleoside hydrolase RED_N PF07808.13 EAQ92749.1 - 1.5e-07 31.3 9.9 1.5e-07 31.3 9.9 2.7 3 0 0 3 3 3 1 RED-like protein N-terminal region Lsm_interact PF05391.11 EAQ92749.1 - 0.15 11.6 1.0 0.46 10.1 1.0 1.9 1 0 0 1 1 1 0 Lsm interaction motif IMS PF00817.20 EAQ92750.1 - 3e-37 127.9 0.0 6.3e-37 126.9 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family REV1_C PF16727.5 EAQ92750.1 - 2.9e-25 88.5 4.9 6e-25 87.5 4.9 1.6 1 0 0 1 1 1 1 DNA repair protein REV1 C-terminal domain IMS_C PF11799.8 EAQ92750.1 - 6.6e-14 52.6 0.0 1.4e-13 51.6 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain UBM PF14377.6 EAQ92750.1 - 1.2e-13 50.0 7.4 7.9e-07 28.3 0.1 3.6 3 0 0 3 3 3 3 Ubiquitin binding region BRCT_2 PF16589.5 EAQ92750.1 - 4.6e-07 30.2 0.0 1e-06 29.0 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 EAQ92750.1 - 0.0038 17.5 0.0 0.0088 16.3 0.0 1.6 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain mCpol PF18182.1 EAQ92750.1 - 0.0056 17.0 0.0 0.012 15.9 0.0 1.5 1 0 0 1 1 1 1 minimal CRISPR polymerase domain IMS_HHH PF11798.8 EAQ92750.1 - 0.015 15.6 0.3 0.09 13.1 0.0 2.5 2 0 0 2 2 2 0 IMS family HHH motif PTCB-BRCT PF12738.7 EAQ92750.1 - 0.046 13.7 0.0 0.13 12.2 0.0 1.8 2 0 0 2 2 2 0 twin BRCT domain BRCT PF00533.26 EAQ92750.1 - 0.052 13.9 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain Peptidase_M3 PF01432.20 EAQ92751.1 - 2.1e-101 340.5 0.0 5.7e-101 339.0 0.0 1.7 2 0 0 2 2 2 1 Peptidase family M3 Peptidase_M50B PF13398.6 EAQ92751.1 - 0.022 14.4 0.1 0.036 13.7 0.1 1.3 1 0 0 1 1 1 0 Peptidase M50B-like ApoO PF09769.9 EAQ92752.1 - 7.3e-35 119.8 2.2 5.8e-34 116.9 0.1 2.1 1 1 1 2 2 2 2 Apolipoprotein O Mito_carr PF00153.27 EAQ92753.1 - 6.7e-46 154.2 5.7 4e-21 74.7 0.0 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein Sod_Fe_C PF02777.18 EAQ92755.1 - 7.5e-14 51.7 0.0 7.8e-06 26.0 0.0 2.5 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain SAM_2 PF07647.17 EAQ92756.1 - 0.0021 18.1 0.0 0.0087 16.2 0.0 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) PH PF00169.29 EAQ92756.1 - 0.011 16.2 0.0 0.31 11.6 0.0 2.6 1 1 0 1 1 1 0 PH domain SAM_1 PF00536.30 EAQ92756.1 - 0.048 14.1 0.0 0.12 12.8 0.0 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) PH_9 PF15410.6 EAQ92756.1 - 0.12 12.8 0.0 1.8 9.0 0.0 2.2 2 0 0 2 2 2 0 Pleckstrin homology domain Fungal_trans_2 PF11951.8 EAQ92758.1 - 3e-78 263.3 0.0 3.8e-78 263.0 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EAQ92758.1 - 9.8e-08 32.0 5.6 1.6e-07 31.3 5.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FerI PF08151.12 EAQ92758.1 - 0.2 11.8 0.0 0.42 10.7 0.0 1.4 1 0 0 1 1 1 0 FerI (NUC094) domain Haemadin PF09065.10 EAQ92760.1 - 0.0082 15.9 6.6 0.02 14.7 6.6 1.7 1 0 0 1 1 1 1 Haemadin SPX PF03105.19 EAQ92760.1 - 0.03 14.3 1.2 0.042 13.8 1.2 1.1 1 0 0 1 1 1 0 SPX domain Insulin_TMD PF17870.1 EAQ92760.1 - 0.095 12.8 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment RAP1 PF07218.11 EAQ92760.1 - 0.94 7.7 2.1 1.2 7.3 2.1 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Aldo_ket_red PF00248.21 EAQ92763.1 - 6.3e-55 186.4 0.0 7.4e-55 186.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family AidB_N PF18158.1 EAQ92763.1 - 0.14 12.1 0.0 0.59 10.0 0.0 1.9 2 0 0 2 2 2 0 Adaptive response protein AidB N-terminal domain PIF1 PF05970.14 EAQ92764.1 - 1.7e-11 43.9 0.8 5e-06 25.9 0.0 2.8 4 0 0 4 4 4 2 PIF1-like helicase WD40 PF00400.32 EAQ92765.1 - 8.5e-137 441.0 69.7 4.6e-11 43.1 0.1 16.3 17 0 0 17 17 15 13 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAQ92765.1 - 1e-56 189.2 3.6 0.0002 21.6 0.0 12.5 2 2 9 12 12 12 12 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EAQ92765.1 - 6.5e-38 130.5 20.8 0.053 12.5 0.0 12.2 3 3 9 12 12 12 12 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 EAQ92765.1 - 2.7e-24 84.5 33.8 2.6 8.1 0.0 13.5 13 0 0 13 13 13 12 WD40-like Beta Propeller Repeat NACHT PF05729.12 EAQ92765.1 - 2.6e-21 76.3 1.0 7.5e-21 74.8 1.0 1.8 1 1 0 1 1 1 1 NACHT domain PNP_UDP_1 PF01048.20 EAQ92765.1 - 1e-13 51.1 0.1 1.6e-13 50.4 0.1 1.3 1 0 0 1 1 1 1 Phosphorylase superfamily Proteasome_A_N PF10584.9 EAQ92765.1 - 6.4e-09 35.3 6.9 2.2e+02 1.7 0.0 12.2 13 0 0 13 13 13 0 Proteasome subunit A N-terminal signature DUF202 PF02656.15 EAQ92765.1 - 5.6e-06 26.7 0.2 5.6e-06 26.7 0.2 2.2 2 0 0 2 2 1 1 Domain of unknown function (DUF202) Glyco_hydro_106 PF17132.4 EAQ92765.1 - 0.0024 16.3 5.0 0.87 7.8 0.1 3.7 4 0 0 4 4 4 2 alpha-L-rhamnosidase AAA_22 PF13401.6 EAQ92765.1 - 0.1 12.9 0.1 1.9 8.8 0.0 2.5 1 1 0 2 2 2 0 AAA domain Importin_rep_3 PF18806.1 EAQ92765.1 - 0.18 11.8 0.1 9.1 6.4 0.0 3.0 4 0 0 4 4 3 0 Importin 13 repeat AAA_11 PF13086.6 EAQ92766.1 - 4.9e-58 197.0 0.0 5.2e-57 193.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.6 EAQ92766.1 - 3.1e-55 186.9 0.0 9.1e-55 185.4 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EAQ92766.1 - 1.6e-10 41.0 0.0 2.8e-09 37.0 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAQ92766.1 - 9.8e-07 29.2 0.0 7.9e-06 26.3 0.0 2.6 3 1 0 3 3 2 1 AAA domain Viral_helicase1 PF01443.18 EAQ92766.1 - 1.7e-06 27.9 0.0 0.72 9.6 0.0 3.3 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 EAQ92766.1 - 9.4e-06 25.1 0.1 5.5e-05 22.6 0.1 2.1 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 EAQ92766.1 - 2.1e-05 24.6 0.0 0.00012 22.2 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 EAQ92766.1 - 0.00012 21.7 0.0 0.00046 19.8 0.0 1.7 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_22 PF13401.6 EAQ92766.1 - 0.00013 22.3 0.1 0.0012 19.1 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EAQ92766.1 - 0.00076 19.9 0.1 0.0019 18.6 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 EAQ92766.1 - 0.0032 17.1 0.5 0.45 10.0 0.0 3.3 2 1 1 3 3 3 1 AAA domain DEAD PF00270.29 EAQ92766.1 - 0.0032 17.3 0.0 0.09 12.5 0.0 2.3 1 1 1 2 2 2 1 DEAD/DEAH box helicase Helicase_RecD PF05127.14 EAQ92766.1 - 0.0033 17.3 0.0 0.19 11.6 0.0 2.4 2 0 0 2 2 2 1 Helicase UvrD_C_2 PF13538.6 EAQ92766.1 - 0.0063 16.3 0.0 0.25 11.2 0.0 2.6 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain Flavi_DEAD PF07652.14 EAQ92766.1 - 0.0081 16.1 0.0 0.023 14.7 0.0 1.8 1 0 0 1 1 1 1 Flavivirus DEAD domain AAA_24 PF13479.6 EAQ92766.1 - 0.0087 15.8 0.0 0.028 14.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain T2SSE PF00437.20 EAQ92766.1 - 0.01 14.9 0.0 0.02 14.0 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein UvrD_C PF13361.6 EAQ92766.1 - 0.017 14.5 0.0 2.1 7.6 0.0 2.7 3 0 0 3 3 3 0 UvrD-like helicase C-terminal domain AAA PF00004.29 EAQ92766.1 - 0.023 15.1 0.0 0.08 13.4 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EAQ92766.1 - 0.028 14.4 0.0 0.12 12.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) PhoH PF02562.16 EAQ92766.1 - 0.058 12.8 0.0 0.41 10.0 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein IstB_IS21 PF01695.17 EAQ92766.1 - 0.065 13.0 0.0 0.18 11.6 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein 4HB_MCP_1 PF12729.7 EAQ92766.1 - 0.12 12.0 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction TrwB_AAD_bind PF10412.9 EAQ92766.1 - 0.12 11.2 0.0 0.21 10.4 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_6 PF12774.7 EAQ92766.1 - 0.15 11.0 0.0 0.95 8.4 0.0 2.0 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region Ribosomal_L30_N PF08079.12 EAQ92766.1 - 1.3 9.3 6.6 3.2 8.1 6.6 1.6 1 0 0 1 1 1 0 Ribosomal L30 N-terminal domain ATG16 PF08614.11 EAQ92767.1 - 0.015 15.6 1.2 0.015 15.6 1.2 1.8 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) BST2 PF16716.5 EAQ92767.1 - 0.028 15.0 0.1 0.06 13.9 0.1 1.5 1 0 0 1 1 1 0 Bone marrow stromal antigen 2 betaPIX_CC PF16523.5 EAQ92767.1 - 0.045 13.6 0.1 0.1 12.4 0.1 1.5 1 0 0 1 1 1 0 betaPIX coiled coil SlyX PF04102.12 EAQ92767.1 - 0.1 13.2 0.0 14 6.3 0.0 2.7 2 0 0 2 2 2 0 SlyX Myosin_tail_1 PF01576.19 EAQ92767.1 - 0.11 10.3 0.4 0.16 9.8 0.4 1.1 1 0 0 1 1 1 0 Myosin tail Macoilin PF09726.9 EAQ92767.1 - 0.61 8.6 3.2 0.17 10.4 0.1 1.5 2 0 0 2 2 2 0 Macoilin family DUF737 PF05300.11 EAQ92767.1 - 1.2 9.5 7.6 0.25 11.7 0.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF737) HATPase_c PF02518.26 EAQ92768.1 - 2.7e-06 27.9 0.0 1.7e-05 25.2 0.0 2.1 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Aldedh PF00171.22 EAQ92770.1 - 1.9e-131 438.8 0.1 2.4e-131 438.5 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Asp PF00026.23 EAQ92771.1 - 2.2e-48 165.3 0.1 1.5e-34 119.9 1.6 2.1 1 1 1 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 EAQ92771.1 - 3.3e-10 40.5 3.2 5.8e-06 26.7 0.0 2.5 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 EAQ92771.1 - 0.00075 19.3 0.0 0.0021 17.8 0.0 1.7 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Peptidase_S8 PF00082.22 EAQ92773.1 - 3.9e-19 69.0 0.0 1.1e-18 67.5 0.0 1.7 1 0 0 1 1 1 1 Subtilase family Ank_2 PF12796.7 EAQ92773.1 - 1.7e-06 28.5 0.0 0.0015 19.1 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 EAQ92773.1 - 0.00021 21.6 0.3 0.014 15.9 0.0 3.6 4 0 0 4 4 4 1 Ankyrin repeat Ank_3 PF13606.6 EAQ92773.1 - 0.011 16.2 0.4 1.5 9.6 0.0 3.9 5 0 0 5 5 5 0 Ankyrin repeat Ank_5 PF13857.6 EAQ92773.1 - 0.012 16.0 0.0 0.28 11.5 0.0 2.9 2 1 0 2 2 2 0 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAQ92773.1 - 0.064 13.9 0.0 5.3 7.7 0.0 3.1 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAQ92775.1 - 8.9e-53 176.8 2.6 5.4e-09 36.5 0.1 9.5 4 2 4 9 9 9 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAQ92775.1 - 9.2e-39 131.3 9.9 7.5e-06 26.4 0.0 10.2 8 2 3 11 11 11 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAQ92775.1 - 5.5e-29 97.0 14.7 0.0043 17.5 0.1 13.8 14 1 0 14 14 14 8 Ankyrin repeat Ank_5 PF13857.6 EAQ92775.1 - 6.5e-23 80.5 15.9 0.0019 18.5 0.0 11.8 10 4 4 14 14 14 6 Ankyrin repeats (many copies) Ank PF00023.30 EAQ92775.1 - 5e-20 71.0 24.7 0.026 15.0 0.0 11.9 12 1 0 12 12 12 5 Ankyrin repeat DUF676 PF05057.14 EAQ92775.1 - 1.7e-05 24.5 0.0 3e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) SdiA-regulated PF06977.11 EAQ92775.1 - 0.032 13.5 0.0 0.063 12.5 0.0 1.4 1 0 0 1 1 1 0 SdiA-regulated PGAP1 PF07819.13 EAQ92775.1 - 0.075 12.7 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein ZZ PF00569.17 EAQ92775.1 - 0.19 11.6 8.0 0.43 10.4 8.0 1.6 1 0 0 1 1 1 0 Zinc finger, ZZ type ANAPC_CDC26 PF10471.9 EAQ92776.1 - 3.1e-15 56.7 0.8 3.1e-15 56.7 0.8 2.3 2 1 0 2 2 2 1 Anaphase-promoting complex APC subunit CDC26 Cwf_Cwc_15 PF04889.12 EAQ92776.1 - 1.5 8.5 7.9 2.9 7.6 7.9 1.4 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Peptidase_M1_N PF17900.1 EAQ92777.1 - 2.8e-07 30.9 0.2 0.0079 16.4 0.0 2.8 3 0 0 3 3 3 2 Peptidase M1 N-terminal domain SAS4 PF15460.6 EAQ92779.1 - 2e-29 101.6 0.0 5.4e-29 100.2 0.0 1.8 1 0 0 1 1 1 1 Something about silencing, SAS, complex subunit 4 PEHE PF15275.6 EAQ92779.1 - 1.8 9.2 0.0 1.8 9.2 0.0 3.6 3 2 0 3 3 3 0 PEHE domain DUF1491 PF07372.12 EAQ92779.1 - 6.5 7.2 6.8 1.3 9.4 2.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1491) Filament PF00038.21 EAQ92780.1 - 0.0045 16.6 9.9 0.0045 16.6 9.9 6.3 4 2 0 5 5 5 3 Intermediate filament protein FIVAR PF07554.13 EAQ92780.1 - 0.029 15.1 2.5 0.21 12.4 0.1 3.1 2 0 0 2 2 2 0 FIVAR domain IBR PF01485.21 EAQ92781.1 - 2e-09 37.5 38.7 8.7e-07 29.1 5.8 3.8 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 EAQ92781.1 - 0.0016 18.7 6.9 0.0016 18.7 6.9 3.7 3 1 1 4 4 4 1 Ring finger domain 3Beta_HSD PF01073.19 EAQ92782.1 - 4.8e-21 75.0 0.0 2.5e-20 72.6 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EAQ92782.1 - 4.3e-09 36.2 0.0 1.1e-08 34.8 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 EAQ92782.1 - 1.8e-06 27.3 0.0 6.3e-06 25.6 0.0 1.7 2 0 0 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.6 EAQ92782.1 - 3.4e-05 23.8 0.0 0.00012 22.0 0.0 2.1 1 1 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 EAQ92782.1 - 0.0042 17.0 0.3 0.016 15.1 0.3 1.8 1 1 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 EAQ92782.1 - 0.0072 15.8 0.0 0.016 14.7 0.0 1.5 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Peptidase_C97 PF05903.14 EAQ92783.1 - 1.8e-34 118.8 0.0 2.2e-34 118.4 0.0 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.13 EAQ92783.1 - 0.00075 19.8 0.0 0.0012 19.2 0.0 1.2 1 0 0 1 1 1 1 Lecithin retinol acyltransferase YchF-GTPase_C PF06071.13 EAQ92784.1 - 1.8e-34 117.8 0.6 4.3e-34 116.6 0.0 2.0 2 1 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 EAQ92784.1 - 2.9e-16 59.6 0.0 8.6e-16 58.0 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EAQ92784.1 - 0.0012 18.4 0.0 0.0021 17.6 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.21 EAQ92784.1 - 0.0023 17.9 0.1 0.0063 16.5 0.1 1.8 1 0 0 1 1 1 1 TGS domain BetaGal_dom3 PF13363.6 EAQ92784.1 - 0.14 11.7 0.0 0.33 10.6 0.0 1.5 1 0 0 1 1 1 0 Beta-galactosidase, domain 3 AAA_23 PF13476.6 EAQ92784.1 - 0.4 11.2 4.5 5.2 7.5 4.3 2.2 1 1 0 1 1 1 0 AAA domain VPS9 PF02204.18 EAQ92785.1 - 1e-21 77.1 0.0 2.6e-21 75.8 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ank_5 PF13857.6 EAQ92785.1 - 1.2e-18 66.9 0.0 6.5e-13 48.6 0.0 5.5 5 1 1 6 6 6 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAQ92785.1 - 1.7e-11 44.5 0.1 0.0074 16.9 0.0 3.8 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAQ92785.1 - 1.3e-07 32.1 0.1 0.035 14.7 0.0 5.0 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAQ92785.1 - 5.6e-06 26.3 0.3 0.42 11.3 0.0 5.5 6 0 0 6 6 6 1 Ankyrin repeat PX PF00787.24 EAQ92785.1 - 0.00016 21.7 0.1 0.00046 20.2 0.1 1.8 1 0 0 1 1 1 1 PX domain Ank PF00023.30 EAQ92785.1 - 0.0012 19.2 0.2 3.8 8.1 0.0 4.2 4 0 0 4 4 4 1 Ankyrin repeat PKS_DE PF18369.1 EAQ92785.1 - 0.12 13.0 2.4 2.5 8.7 0.0 3.9 3 0 0 3 3 3 0 Polyketide synthase dimerisation element domain ketoacyl-synt PF00109.26 EAQ92786.1 - 9.3e-71 238.4 0.5 9.3e-71 238.4 0.5 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.6 EAQ92786.1 - 5.2e-42 144.1 0.2 2.6e-29 102.4 0.0 2.3 1 1 1 2 2 2 2 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 EAQ92786.1 - 3.8e-37 126.9 0.9 8.8e-37 125.7 0.2 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 EAQ92786.1 - 4.8e-16 59.2 0.0 1.2e-15 58.0 0.0 1.6 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Acyl_transf_1 PF00698.21 EAQ92786.1 - 6.8e-13 48.8 0.9 9.6e-07 28.6 0.1 3.3 2 1 1 3 3 3 3 Acyl transferase domain Methyltransf_12 PF08242.12 EAQ92786.1 - 7.2e-08 33.1 0.0 2.5e-07 31.3 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EAQ92786.1 - 2.6e-06 27.4 0.0 5.5e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 EAQ92786.1 - 1.4e-05 25.3 0.0 0.0001 22.6 0.0 2.5 2 0 0 2 2 2 1 Phosphopantetheine attachment site Methyltransf_11 PF08241.12 EAQ92786.1 - 0.00032 21.3 0.0 0.0012 19.5 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAQ92786.1 - 0.00041 20.2 0.0 0.00089 19.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.23 EAQ92786.1 - 0.0019 17.6 0.8 0.0044 16.4 0.1 1.9 2 0 0 2 2 2 1 Thiolase, N-terminal domain adh_short PF00106.25 EAQ92787.1 - 2.3e-19 69.6 4.2 9.9e-19 67.6 0.5 2.8 3 0 0 3 3 3 1 short chain dehydrogenase adh_short_C2 PF13561.6 EAQ92787.1 - 2.6e-11 43.5 3.1 1.9e-10 40.7 1.3 2.3 2 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EAQ92787.1 - 1.2e-09 38.4 0.8 2.2e-09 37.5 0.8 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EAQ92787.1 - 0.05 13.1 0.0 0.075 12.5 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EAQ92787.1 - 0.088 11.9 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DNA_pol_B_palm PF14792.6 EAQ92789.1 - 3.4e-33 114.2 0.0 6.2e-33 113.4 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.6 EAQ92789.1 - 1.2e-25 89.4 0.3 8.6e-25 86.7 0.6 2.2 2 0 0 2 2 2 1 DNA polymerase beta thumb HHH_8 PF14716.6 EAQ92789.1 - 9.7e-19 67.5 0.2 2.5e-18 66.2 0.2 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.9 EAQ92789.1 - 4e-16 58.6 0.0 1e-15 57.3 0.0 1.7 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda BRCT_2 PF16589.5 EAQ92789.1 - 0.0038 17.6 0.0 0.0077 16.6 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain NTP_transf_2 PF01909.23 EAQ92789.1 - 0.05 13.9 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 Nucleotidyltransferase domain DUF3292 PF11696.8 EAQ92789.1 - 0.18 10.2 2.4 0.29 9.4 2.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) Mob1_phocein PF03637.17 EAQ92790.1 - 7.3e-44 149.8 0.4 1.7e-43 148.6 0.4 1.5 1 1 0 1 1 1 1 Mob1/phocein family Methyltransf_25 PF13649.6 EAQ92791.1 - 1.5e-11 44.9 0.0 4e-11 43.5 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain PrmA PF06325.13 EAQ92791.1 - 4.3e-11 42.8 0.0 6.1e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 EAQ92791.1 - 1.2e-10 41.4 0.0 2.4e-10 40.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EAQ92791.1 - 7.4e-08 32.9 0.0 2.7e-07 31.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.11 EAQ92791.1 - 2.6e-07 29.9 0.1 3.9e-07 29.3 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_23 PF13489.6 EAQ92791.1 - 2.5e-06 27.5 0.0 6.2e-06 26.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.7 EAQ92791.1 - 4.5e-05 23.4 0.2 0.0001 22.3 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EAQ92791.1 - 6.2e-05 22.6 0.0 0.00011 21.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 EAQ92791.1 - 0.00027 21.6 0.0 0.00057 20.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EAQ92791.1 - 0.00031 20.1 0.0 0.00045 19.6 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase FtsJ PF01728.19 EAQ92791.1 - 0.00093 19.3 0.1 0.0014 18.7 0.1 1.5 1 1 0 1 1 1 1 FtsJ-like methyltransferase PRMT5 PF05185.16 EAQ92791.1 - 0.0018 18.2 0.1 0.0043 16.9 0.1 1.6 1 1 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_C PF17286.2 EAQ92791.1 - 0.0084 16.0 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 PRMT5 oligomerisation domain Methyltransf_32 PF13679.6 EAQ92791.1 - 0.014 15.4 0.0 0.024 14.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 EAQ92791.1 - 0.018 14.8 0.2 0.028 14.2 0.2 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.9 EAQ92791.1 - 0.026 14.3 0.1 0.04 13.7 0.1 1.3 1 0 0 1 1 1 0 Lysine methyltransferase DOT1 PF08123.13 EAQ92791.1 - 0.051 13.1 0.1 0.084 12.4 0.1 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 TehB PF03848.14 EAQ92791.1 - 0.058 12.8 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 Tellurite resistance protein TehB Met_10 PF02475.16 EAQ92791.1 - 0.069 12.9 0.1 0.1 12.3 0.1 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_15 PF09445.10 EAQ92791.1 - 0.085 12.4 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Cons_hypoth95 PF03602.15 EAQ92791.1 - 0.086 12.5 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 RrnaAD PF00398.20 EAQ92791.1 - 0.089 11.8 0.0 0.21 10.6 0.0 1.7 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase PGM_PMM_IV PF00408.20 EAQ92792.1 - 1.7e-12 47.3 0.4 4.8e-12 45.9 0.4 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_I PF02878.16 EAQ92792.1 - 1.6e-09 37.6 0.1 8.7e-08 32.0 0.0 2.4 1 1 1 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 EAQ92792.1 - 0.018 15.6 0.4 1 10.0 0.3 3.1 2 1 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 EAQ92792.1 - 0.021 15.0 0.1 0.088 13.0 0.1 2.1 1 1 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III T3SS_ATPase_C PF18269.1 EAQ92792.1 - 0.15 11.9 0.0 31 4.5 0.0 2.8 3 0 0 3 3 3 0 T3SS EscN ATPase C-terminal domain ERCC4 PF02732.15 EAQ92793.1 - 8.5e-25 87.8 0.0 1.3e-24 87.2 0.0 1.3 1 0 0 1 1 1 1 ERCC4 domain HHH_8 PF14716.6 EAQ92793.1 - 0.018 15.4 0.0 0.048 14.0 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix domain HHH_5 PF14520.6 EAQ92793.1 - 0.089 13.4 0.0 0.21 12.2 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix domain Lum_binding PF00677.17 EAQ92794.1 - 5.4e-45 151.3 1.0 3.8e-23 81.3 0.1 2.1 2 0 0 2 2 2 2 Lumazine binding domain Glyco_transf_17 PF04724.13 EAQ92795.1 - 4.3e-36 124.7 0.0 5.6e-36 124.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 17 UPF0258 PF06789.12 EAQ92795.1 - 0.063 13.4 0.1 0.098 12.8 0.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0258) SecG PF03840.14 EAQ92795.1 - 0.41 10.8 1.0 0.64 10.1 0.3 1.6 2 0 0 2 2 2 0 Preprotein translocase SecG subunit Peptidase_C15 PF01470.17 EAQ92796.1 - 0.00037 20.7 0.0 0.00049 20.3 0.0 1.1 1 0 0 1 1 1 1 Pyroglutamyl peptidase Oxidored_FMN PF00724.20 EAQ92797.1 - 1.2e-65 222.1 0.0 2.6e-62 211.1 0.0 2.1 2 0 0 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family XPG_N PF00752.17 EAQ92800.1 - 8e-32 109.7 0.0 1.6e-31 108.8 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain DUF2401 PF10287.9 EAQ92800.1 - 4.4e-26 91.9 0.2 1e-25 90.7 0.2 1.6 1 0 0 1 1 1 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.9 EAQ92800.1 - 9.2e-26 90.1 0.1 2.5e-25 88.7 0.1 1.8 1 0 0 1 1 1 1 Glycine-rich protein domain (DUF2403) XPG_I PF00867.18 EAQ92800.1 - 1.8e-20 73.1 0.0 5.6e-20 71.5 0.0 1.8 1 0 0 1 1 1 1 XPG I-region UIM PF02809.20 EAQ92800.1 - 0.0002 21.0 1.0 0.0002 21.0 1.0 4.1 4 0 0 4 4 4 1 Ubiquitin interaction motif HHH PF00633.23 EAQ92800.1 - 0.16 11.9 0.1 0.39 10.7 0.1 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif DUF2229 PF09989.9 EAQ92800.1 - 0.18 11.4 0.1 0.5 10.0 0.1 1.7 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) LSM PF01423.22 EAQ92801.1 - 1.9e-09 37.1 0.1 9.9e-09 34.8 0.1 2.0 1 1 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EAQ92801.1 - 0.043 14.0 0.0 0.1 12.8 0.0 1.9 1 1 0 1 1 1 0 Ataxin 2 SM domain Gemini_C4 PF01492.17 EAQ92801.1 - 0.2 11.6 2.9 0.42 10.6 2.9 1.4 1 0 0 1 1 1 0 Geminivirus C4 protein Pil1 PF13805.6 EAQ92802.1 - 8.3e-101 336.9 3.3 1.1e-100 336.5 3.3 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 EZH2_N PF18601.1 EAQ92803.1 - 1.5e-32 111.7 0.0 4.5e-32 110.2 0.0 1.8 1 0 0 1 1 1 1 EZH2 N-terminal domain Ezh2_MCSS PF18600.1 EAQ92803.1 - 1.7e-24 85.2 0.6 3.2e-24 84.3 0.6 1.5 1 0 0 1 1 1 1 MCSS domain SET PF00856.28 EAQ92803.1 - 5.4e-17 62.7 2.3 1.8e-16 61.0 0.3 3.0 2 1 0 2 2 2 1 SET domain preSET_CXC PF18264.1 EAQ92803.1 - 3.1e-05 24.3 13.0 3.1e-05 24.3 13.0 3.4 2 1 2 4 4 4 1 CXC domain WD40 PF00400.32 EAQ92804.1 - 2.2e-09 37.8 9.5 1.1 10.3 0.0 9.5 10 0 0 10 10 10 2 WD domain, G-beta repeat R2K_3 PF14243.6 EAQ92804.1 - 0.1 12.6 0.1 0.2 11.6 0.1 1.4 1 0 0 1 1 1 0 ATP-grasp domain, R2K clade family 3 SUR7 PF06687.12 EAQ92805.1 - 1.2e-39 136.1 7.2 1.6e-39 135.8 7.2 1.1 1 0 0 1 1 1 1 SUR7/PalI family Metallophos PF00149.28 EAQ92807.1 - 1.4e-34 120.4 0.0 2.4e-34 119.7 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EAQ92807.1 - 2.2e-14 53.6 0.0 3.7e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Glyco_transf_22 PF03901.17 EAQ92808.1 - 9.9e-28 97.5 8.3 1.3e-27 97.1 8.3 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family F_actin_cap_B PF01115.17 EAQ92809.1 - 1.2e-104 349.2 0.0 1.4e-104 349.0 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit Epimerase PF01370.21 EAQ92810.1 - 9.4e-17 61.3 0.0 1.3e-16 60.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EAQ92810.1 - 1.4e-06 27.6 0.0 1.8e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 EAQ92810.1 - 0.00012 21.6 0.0 0.00019 20.9 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EAQ92810.1 - 0.0023 17.0 0.0 0.0044 16.1 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Mito_carr PF00153.27 EAQ92813.1 - 1.5e-48 162.7 7.6 3.1e-17 62.3 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Glyco_transf_28 PF03033.20 EAQ92814.1 - 1.3e-20 73.9 0.5 1.7e-11 44.3 0.0 2.5 2 0 0 2 2 2 2 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 EAQ92814.1 - 1.4e-05 24.1 0.2 2.2e-05 23.5 0.2 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 EAQ92814.1 - 0.00012 22.1 0.0 0.00076 19.5 0.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase family 28 C-terminal domain ATG_C PF09333.11 EAQ92814.1 - 0.0023 18.2 0.0 0.0097 16.2 0.0 2.1 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain VPS13_C PF16909.5 EAQ92814.1 - 0.23 11.2 0.4 0.5 10.1 0.4 1.5 1 0 0 1 1 1 0 Vacuolar-sorting-associated 13 protein C-terminal RAP80_UIM PF18282.1 EAQ92814.1 - 1.7 8.5 10.2 1 9.2 0.2 2.5 2 0 0 2 2 2 0 RAP80 N-terminal ubiquitin interaction motif SnoaL_4 PF13577.6 EAQ92815.1 - 2.2e-19 69.8 0.0 2.6e-19 69.6 0.0 1.0 1 0 0 1 1 1 1 SnoaL-like domain NAD_binding_10 PF13460.6 EAQ92816.1 - 1.3e-13 51.2 0.0 3.2e-13 50.0 0.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EAQ92816.1 - 8.8e-12 45.1 0.0 6.1e-11 42.3 0.0 2.0 1 1 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 EAQ92816.1 - 2.4e-06 27.2 0.0 4.8e-05 22.9 0.0 2.5 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 EAQ92816.1 - 6e-05 23.3 0.0 0.00012 22.3 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain KR PF08659.10 EAQ92816.1 - 8.5e-05 22.5 0.0 0.00016 21.6 0.0 1.4 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.17 EAQ92816.1 - 0.001 19.6 0.0 0.0042 17.6 0.0 2.0 2 1 1 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent Polysacc_synt_2 PF02719.15 EAQ92816.1 - 0.01 15.0 0.0 0.022 13.9 0.0 1.5 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.24 EAQ92816.1 - 0.045 14.2 0.0 0.11 13.0 0.0 1.7 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 EAQ92816.1 - 0.051 13.0 0.0 0.46 9.8 0.0 2.0 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Red1 PF07964.11 EAQ92816.1 - 0.06 11.6 0.0 0.079 11.2 0.0 1.1 1 0 0 1 1 1 0 Rec10 / Red1 Shikimate_DH PF01488.20 EAQ92816.1 - 0.13 12.3 0.0 0.26 11.3 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase TPP_enzyme_M PF00205.22 EAQ92816.1 - 0.15 11.8 0.0 1.8 8.3 0.0 2.2 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain PAS_3 PF08447.12 EAQ92816.1 - 0.19 12.1 0.0 0.37 11.1 0.0 1.4 1 0 0 1 1 1 0 PAS fold PAF-AH_p_II PF03403.13 EAQ92817.1 - 8.7e-52 175.9 0.0 1.2e-24 86.5 0.0 4.0 4 0 0 4 4 4 3 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 EAQ92817.1 - 2.3e-07 30.0 0.0 3.8e-05 22.7 0.0 2.2 2 0 0 2 2 2 2 Chlorophyllase enzyme Hydrolase_4 PF12146.8 EAQ92817.1 - 0.00029 20.2 0.0 0.23 10.7 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Chlorophyllase PF07224.11 EAQ92817.1 - 0.00061 18.9 0.0 0.011 14.8 0.0 2.1 2 0 0 2 2 2 1 Chlorophyllase Abhydrolase_6 PF12697.7 EAQ92817.1 - 0.0028 18.3 0.4 0.0028 18.3 0.4 2.4 2 1 2 4 4 4 1 Alpha/beta hydrolase family Mito_carr PF00153.27 EAQ92820.1 - 4.4e-25 87.4 0.1 4.5e-12 45.7 0.0 3.0 2 1 1 3 3 3 2 Mitochondrial carrier protein DUF1708 PF08101.11 EAQ92821.1 - 4.9e-142 474.1 0.0 6.9e-142 473.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) UDG PF03167.19 EAQ92822.1 - 3.1e-22 79.2 0.1 5.4e-22 78.4 0.1 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily CDC27 PF09507.10 EAQ92822.1 - 0.067 12.6 0.4 0.067 12.6 0.4 1.6 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 Metallophos PF00149.28 EAQ92823.1 - 1e-12 49.0 0.3 1.8e-12 48.2 0.3 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Serglycin PF04360.12 EAQ92823.1 - 3.7 7.5 8.8 0.15 12.0 0.5 2.4 3 0 0 3 3 3 0 Serglycin Glyco_hydro_3_C PF01915.22 EAQ92824.1 - 1.8e-66 224.0 0.0 4.3e-66 222.8 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EAQ92824.1 - 2.5e-57 194.7 0.0 4.3e-57 193.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain PA14 PF07691.12 EAQ92824.1 - 3.2e-25 88.6 0.0 5.5e-25 87.9 0.0 1.4 1 0 0 1 1 1 1 PA14 domain Fn3-like PF14310.6 EAQ92824.1 - 6.2e-23 80.7 0.1 1.8e-22 79.2 0.1 1.9 1 0 0 1 1 1 1 Fibronectin type III-like domain GLEYA PF10528.9 EAQ92824.1 - 0.062 13.7 0.0 0.29 11.6 0.0 2.2 3 0 0 3 3 3 0 GLEYA domain RRF PF01765.19 EAQ92827.1 - 2.8e-30 105.4 0.1 3.6e-30 105.1 0.1 1.1 1 0 0 1 1 1 1 Ribosome recycling factor DUF3090 PF11290.8 EAQ92827.1 - 0.1 12.4 0.3 0.22 11.3 0.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3090) PHD PF00628.29 EAQ92828.1 - 0.014 15.3 2.5 0.036 14.0 2.5 1.7 1 0 0 1 1 1 0 PHD-finger zf-HC5HC2H PF13771.6 EAQ92828.1 - 0.1 12.9 1.1 0.22 11.8 1.1 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain ATG22 PF11700.8 EAQ92829.1 - 5.7e-187 622.1 9.5 6.6e-187 621.9 9.5 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 EAQ92829.1 - 1.4e-05 24.3 42.5 0.015 14.3 6.7 3.2 2 1 1 3 3 3 3 Major Facilitator Superfamily TRAP-gamma PF07074.12 EAQ92829.1 - 0.0029 17.2 0.9 0.0081 15.7 0.9 1.7 1 0 0 1 1 1 1 Translocon-associated protein, gamma subunit (TRAP-gamma) Phage_holin_3_6 PF07332.11 EAQ92829.1 - 0.37 10.8 0.0 0.37 10.8 0.0 3.5 3 1 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III DUF3602 PF12223.8 EAQ92830.1 - 1.3e-22 80.2 11.6 2e-22 79.5 4.3 2.5 1 1 1 2 2 2 2 Protein of unknown function (DUF3602) FAA_hydrolase PF01557.18 EAQ92832.1 - 8e-64 215.3 0.0 1e-63 214.9 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family DUF3724 PF12521.8 EAQ92832.1 - 0.26 11.3 1.1 0.93 9.5 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3724) Sugar_tr PF00083.24 EAQ92834.1 - 5.7e-84 282.6 16.9 6.9e-84 282.3 16.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EAQ92834.1 - 8.7e-28 97.2 18.9 1.3e-27 96.7 18.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 EAQ92834.1 - 6.7e-05 21.5 3.1 0.00025 19.6 0.7 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) PTR2 PF00854.21 EAQ92834.1 - 0.065 12.1 7.2 0.11 11.3 0.8 2.3 2 0 0 2 2 2 0 POT family OATP PF03137.20 EAQ92834.1 - 0.31 9.3 7.1 1.8 6.8 6.8 2.5 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family MutS_V PF00488.21 EAQ92835.1 - 1.4e-69 233.9 0.4 4.6e-69 232.2 0.2 2.0 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.18 EAQ92835.1 - 5.1e-35 121.4 0.8 1.1e-34 120.4 0.8 1.6 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 EAQ92835.1 - 2.4e-30 105.1 0.4 5.3e-30 104.0 0.0 1.8 2 0 0 2 2 2 1 MutS domain I MutS_II PF05188.17 EAQ92835.1 - 6.2e-10 39.5 0.0 1.4e-09 38.3 0.0 1.7 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 EAQ92835.1 - 0.001 19.4 0.0 0.0025 18.1 0.0 1.7 1 0 0 1 1 1 1 MutS family domain IV DUF4911 PF16256.5 EAQ92835.1 - 0.17 11.9 0.0 0.37 10.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4911) zf-C2H2 PF00096.26 EAQ92836.1 - 0.096 13.2 1.5 0.2 12.2 1.5 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-SCNM1 PF15803.5 EAQ92836.1 - 0.43 10.3 1.6 0.68 9.6 1.6 1.3 1 0 0 1 1 1 0 Zinc-finger of sodium channel modifier 1 Prenyltrans PF00432.21 EAQ92837.1 - 1.4e-54 181.5 7.9 6.5e-12 45.0 0.0 6.1 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 EAQ92837.1 - 6e-05 22.3 0.1 0.091 11.8 0.0 3.4 2 1 2 4 4 4 3 Squalene-hopene cyclase N-terminal domain RhoGAP PF00620.27 EAQ92838.1 - 4.1e-29 101.4 0.0 6.4e-29 100.7 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain Mucin PF01456.17 EAQ92838.1 - 0.81 9.7 5.0 0.16 11.9 0.2 2.2 2 0 0 2 2 2 0 Mucin-like glycoprotein RRS1 PF04939.12 EAQ92839.1 - 3.5e-53 179.8 0.3 4.1e-53 179.6 0.3 1.0 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) U-box PF04564.15 EAQ92839.1 - 0.084 13.1 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 U-box domain DAP3 PF10236.9 EAQ92840.1 - 6e-106 354.1 0.0 7.4e-106 353.8 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.6 EAQ92840.1 - 0.0034 17.8 0.0 0.0069 16.8 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain MCM PF00493.23 EAQ92841.1 - 3.7e-103 343.5 1.1 4.3e-103 343.2 0.0 1.7 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 EAQ92841.1 - 1.9e-30 105.3 0.4 1.9e-30 105.3 0.4 1.7 2 0 0 2 2 2 1 MCM OB domain MCM_N PF14551.6 EAQ92841.1 - 5e-20 72.0 2.4 5e-20 72.0 2.4 2.1 2 0 0 2 2 2 1 MCM N-terminal domain MCM_lid PF17855.1 EAQ92841.1 - 4.8e-19 68.6 0.8 1e-18 67.5 0.8 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 EAQ92841.1 - 2.9e-07 30.1 0.0 2.3e-05 23.9 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EAQ92841.1 - 7.7e-07 29.2 0.0 3.5e-06 27.1 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_lid_2 PF17863.1 EAQ92841.1 - 0.00075 19.3 0.4 0.0023 17.8 0.4 1.8 1 0 0 1 1 1 1 AAA lid domain AAA_3 PF07726.11 EAQ92841.1 - 0.025 14.4 0.0 0.083 12.7 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase_C PF13335.6 EAQ92841.1 - 0.04 14.5 1.0 0.19 12.4 0.6 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI C-terminal CHASE2 PF05226.11 EAQ92841.1 - 0.04 13.6 0.3 0.17 11.5 0.1 2.0 2 0 0 2 2 2 0 CHASE2 domain PSD5 PF07637.11 EAQ92841.1 - 0.15 12.5 0.2 0.52 10.7 0.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1595) Sigma54_activat PF00158.26 EAQ92841.1 - 0.17 11.6 0.1 0.97 9.1 0.0 2.2 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA PF00004.29 EAQ92842.1 - 7.9e-57 191.3 0.0 3e-43 147.4 0.0 2.7 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.11 EAQ92842.1 - 3.4e-28 97.9 0.2 6.7e-28 96.9 0.2 1.5 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_lid_3 PF17862.1 EAQ92842.1 - 3.1e-15 55.7 0.2 1.7e-09 37.3 0.1 2.7 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 EAQ92842.1 - 7e-10 39.5 9.2 0.00038 20.9 0.1 5.3 4 2 1 6 6 5 2 AAA ATPase domain AAA_7 PF12775.7 EAQ92842.1 - 1.9e-07 30.7 0.0 1e-05 25.2 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_2 PF07724.14 EAQ92842.1 - 4.7e-07 30.1 0.0 0.0097 16.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) NACHT PF05729.12 EAQ92842.1 - 3e-06 27.3 0.3 0.0038 17.1 0.0 3.3 3 1 0 3 3 3 1 NACHT domain AAA_5 PF07728.14 EAQ92842.1 - 7.1e-06 26.1 0.2 0.048 13.7 0.0 3.3 3 1 0 3 3 2 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EAQ92842.1 - 8.7e-06 25.6 0.0 0.014 15.2 0.0 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 EAQ92842.1 - 0.00011 22.2 0.1 0.26 11.3 0.0 2.3 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 EAQ92842.1 - 0.00012 22.3 3.0 0.66 10.3 0.2 4.2 3 2 1 4 4 3 1 AAA domain AAA_18 PF13238.6 EAQ92842.1 - 0.00024 21.6 0.1 0.97 10.0 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_14 PF13173.6 EAQ92842.1 - 0.00027 21.0 0.0 0.78 9.8 0.0 2.8 3 0 0 3 3 2 2 AAA domain Zeta_toxin PF06414.12 EAQ92842.1 - 0.00032 20.0 0.2 0.095 12.0 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin Sigma54_activ_2 PF14532.6 EAQ92842.1 - 0.00035 20.7 0.0 0.024 14.7 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_33 PF13671.6 EAQ92842.1 - 0.00052 20.2 0.3 0.24 11.5 0.0 2.8 2 1 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 EAQ92842.1 - 0.00082 19.1 0.0 0.05 13.3 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_25 PF13481.6 EAQ92842.1 - 0.0026 17.4 3.0 1.2 8.6 0.2 3.6 2 2 2 4 4 4 1 AAA domain TIP49 PF06068.13 EAQ92842.1 - 0.0031 16.8 0.0 1.1 8.4 0.0 2.2 2 0 0 2 2 2 1 TIP49 P-loop domain ATPase PF06745.13 EAQ92842.1 - 0.0036 16.7 0.1 0.96 8.7 0.0 2.4 2 0 0 2 2 2 1 KaiC Mg_chelatase PF01078.21 EAQ92842.1 - 0.0037 16.7 0.1 0.77 9.1 0.1 2.6 3 0 0 3 3 2 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 EAQ92842.1 - 0.004 17.5 0.3 0.12 12.7 0.0 3.0 3 0 0 3 3 3 1 AAA domain IstB_IS21 PF01695.17 EAQ92842.1 - 0.0053 16.5 0.1 4.3 7.0 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein NB-ARC PF00931.22 EAQ92842.1 - 0.0055 15.9 0.1 1.2 8.3 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain AAA_17 PF13207.6 EAQ92842.1 - 0.0057 17.1 1.8 2.4 8.6 0.1 2.8 3 0 0 3 3 2 1 AAA domain RNA_helicase PF00910.22 EAQ92842.1 - 0.0062 16.9 0.0 4.9 7.6 0.0 2.8 2 0 0 2 2 2 0 RNA helicase ABC_tran PF00005.27 EAQ92842.1 - 0.013 16.0 0.0 7.1 7.2 0.0 3.0 2 0 0 2 2 2 0 ABC transporter AAA_28 PF13521.6 EAQ92842.1 - 0.023 15.0 0.1 5.4 7.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 EAQ92842.1 - 0.024 13.7 0.1 0.076 12.1 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein PEX-2N PF09263.10 EAQ92842.1 - 0.029 14.7 0.6 3.3 8.1 0.0 2.8 3 0 0 3 3 2 0 Peroxisome biogenesis factor 1, N-terminal KAP_NTPase PF07693.14 EAQ92842.1 - 0.034 13.4 0.3 5 6.3 0.1 2.4 1 1 1 2 2 2 0 KAP family P-loop domain NTPase_1 PF03266.15 EAQ92842.1 - 0.04 13.8 0.1 0.55 10.1 0.0 2.2 2 0 0 2 2 2 0 NTPase DUF2075 PF09848.9 EAQ92842.1 - 0.041 13.1 0.0 8.7 5.5 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.18 EAQ92842.1 - 0.046 13.4 0.0 4.2 7.1 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_29 PF13555.6 EAQ92842.1 - 0.053 13.3 0.0 0.82 9.5 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF815 PF05673.13 EAQ92842.1 - 0.062 12.4 0.0 0.84 8.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_24 PF13479.6 EAQ92842.1 - 0.066 12.9 0.2 13 5.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain CobU PF02283.16 EAQ92842.1 - 0.11 12.1 1.0 0.2 11.2 0.0 1.9 2 0 0 2 2 2 0 Cobinamide kinase / cobinamide phosphate guanyltransferase TrwB_AAD_bind PF10412.9 EAQ92842.1 - 0.14 11.1 0.0 0.33 9.8 0.0 1.5 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_30 PF13604.6 EAQ92842.1 - 0.27 10.9 6.1 0.55 9.9 0.0 3.1 3 0 0 3 3 3 0 AAA domain Ank_2 PF12796.7 EAQ92843.1 - 0.007 16.9 0.0 0.033 14.8 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) VTC PF09359.10 EAQ92845.1 - 3.4e-99 331.7 0.2 6.2e-99 330.8 0.0 1.5 2 0 0 2 2 2 1 VTC domain DUF202 PF02656.15 EAQ92845.1 - 4.5e-13 49.4 3.1 1e-12 48.3 3.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF202) SPX PF03105.19 EAQ92845.1 - 2.6e-11 44.1 10.9 1.5e-05 25.1 0.1 3.9 2 1 1 4 4 4 2 SPX domain HTH_29 PF13551.6 EAQ92845.1 - 0.013 15.5 0.1 0.25 11.4 0.0 2.7 3 0 0 3 3 3 0 Winged helix-turn helix TrmB PF01978.19 EAQ92845.1 - 0.019 14.8 0.6 0.27 11.1 0.1 2.6 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB FixQ PF05545.11 EAQ92845.1 - 0.033 14.2 0.8 0.074 13.0 0.8 1.5 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ Fe_dep_repress PF01325.19 EAQ92845.1 - 0.074 13.3 0.1 0.19 11.9 0.1 1.7 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain Cys_Met_Meta_PP PF01053.20 EAQ92846.1 - 1.2e-17 63.6 0.0 2.3e-17 62.6 0.0 1.4 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 EAQ92846.1 - 1.8e-07 30.7 0.0 2.7e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Hexokinase_2 PF03727.16 EAQ92847.1 - 3.3e-71 239.5 0.0 4.6e-71 239.1 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 EAQ92847.1 - 8e-61 205.4 0.0 1.4e-60 204.7 0.0 1.4 1 0 0 1 1 1 1 Hexokinase FGGY_N PF00370.21 EAQ92847.1 - 0.13 11.8 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain SRR1 PF07985.12 EAQ92848.1 - 3.9e-11 42.8 0.0 8.6e-11 41.7 0.0 1.6 1 0 0 1 1 1 1 SRR1 PCIF1_WW PF12237.8 EAQ92848.1 - 0.071 12.7 0.0 1 8.9 0.0 2.1 2 0 0 2 2 2 0 Phosphorylated CTD interacting factor 1 WW domain Ribophorin_I PF04597.14 EAQ92849.1 - 7.6e-156 519.7 0.3 8.6e-156 519.5 0.3 1.0 1 0 0 1 1 1 1 Ribophorin I Pil1 PF13805.6 EAQ92850.1 - 2.2e-115 384.7 2.7 2.9e-115 384.3 2.7 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 MCM PF00493.23 EAQ92851.1 - 5.7e-36 123.7 0.1 1.2e-19 70.3 0.0 2.0 1 1 1 2 2 2 2 MCM P-loop domain Clat_adaptor_s PF01217.20 EAQ92852.1 - 7.4e-13 48.6 0.1 2e-12 47.3 0.1 1.6 2 0 0 2 2 2 1 Clathrin adaptor complex small chain Pkinase PF00069.25 EAQ92853.1 - 4.4e-52 177.1 0.0 5.8e-52 176.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ92853.1 - 6.2e-40 137.1 0.0 9.2e-40 136.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Sua5_yciO_yrdC PF01300.18 EAQ92853.1 - 5e-07 29.4 0.1 2e-06 27.4 0.0 1.9 2 0 0 2 2 2 1 Telomere recombination Haspin_kinase PF12330.8 EAQ92853.1 - 0.013 14.5 0.0 0.33 9.8 0.0 2.1 2 0 0 2 2 2 0 Haspin like kinase domain Pkinase_fungal PF17667.1 EAQ92853.1 - 0.023 13.5 0.0 0.046 12.5 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 EAQ92853.1 - 0.053 12.9 0.0 0.16 11.3 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EAQ92853.1 - 0.12 11.6 0.0 2.4 7.4 0.0 2.2 2 0 0 2 2 2 0 Kinase-like FAD_binding_3 PF01494.19 EAQ92855.1 - 3.9e-14 52.6 0.1 5.3e-10 39.1 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 EAQ92855.1 - 0.00011 21.4 0.1 0.011 14.8 0.0 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein NAD_binding_9 PF13454.6 EAQ92855.1 - 0.0025 17.8 0.0 0.0054 16.7 0.0 1.6 1 0 0 1 1 1 1 FAD-NAD(P)-binding SE PF08491.10 EAQ92855.1 - 0.0045 16.1 0.0 0.0068 15.5 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase Pyr_redox_2 PF07992.14 EAQ92855.1 - 0.0049 16.1 0.0 0.0068 15.7 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EAQ92855.1 - 0.0099 15.5 0.2 0.043 13.4 0.1 1.9 1 1 0 2 2 2 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 EAQ92855.1 - 0.063 12.4 0.0 0.13 11.4 0.0 1.5 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 EAQ92855.1 - 0.077 12.2 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 Thi4 family NAD_binding_8 PF13450.6 EAQ92855.1 - 0.11 12.7 0.2 0.43 10.9 0.1 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pex14_N PF04695.13 EAQ92856.1 - 0.00024 21.8 13.2 0.00024 21.8 13.2 3.3 3 1 0 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Lin-8 PF03353.15 EAQ92856.1 - 0.004 16.8 6.4 0.004 16.8 6.4 2.0 2 0 0 2 2 2 1 Ras-mediated vulval-induction antagonist DDHD PF02862.17 EAQ92856.1 - 0.0073 16.5 4.4 0.0073 16.5 4.4 2.0 2 0 0 2 2 2 1 DDHD domain SpoIIP PF07454.11 EAQ92856.1 - 0.012 15.1 8.3 0.026 14.0 8.3 1.5 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Maf1 PF09174.10 EAQ92856.1 - 0.015 15.4 2.5 0.015 15.4 2.5 1.7 2 0 0 2 2 1 0 Maf1 regulator MDM10 PF12519.8 EAQ92856.1 - 0.037 12.9 3.4 0.069 12.0 3.4 1.3 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Peptidase_S64 PF08192.11 EAQ92856.1 - 0.2 10.1 6.6 0.11 11.0 3.5 1.8 2 0 0 2 2 2 0 Peptidase family S64 Pet20 PF08692.10 EAQ92856.1 - 0.21 12.3 2.1 0.58 10.9 2.1 1.7 1 0 0 1 1 1 0 Mitochondrial protein Pet20 Otopetrin PF03189.13 EAQ92856.1 - 0.24 10.2 1.2 0.34 9.7 1.2 1.2 1 0 0 1 1 1 0 Otopetrin EPL1 PF10513.9 EAQ92856.1 - 0.35 11.2 16.5 0.072 13.5 9.9 2.3 2 0 0 2 2 2 0 Enhancer of polycomb-like ABC2_membrane_2 PF12679.7 EAQ92856.1 - 0.63 9.3 1.1 0.93 8.7 1.1 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein Band_3_cyto PF07565.13 EAQ92856.1 - 0.99 9.2 11.2 2 8.2 11.2 1.4 1 0 0 1 1 1 0 Band 3 cytoplasmic domain SID-1_RNA_chan PF13965.6 EAQ92856.1 - 2.2 6.6 2.9 3.1 6.1 2.9 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 EOS1 PF12326.8 EAQ92856.1 - 3.5 7.5 7.7 0.34 10.8 3.1 1.6 2 0 0 2 2 2 0 N-glycosylation protein TERB2 PF15101.6 EAQ92856.1 - 3.6 7.6 22.2 0.88 9.6 18.8 1.6 2 0 0 2 2 2 0 Telomere-associated protein TERB2 SLC12 PF03522.15 EAQ92856.1 - 4.9 6.1 13.3 10 5.0 13.3 1.4 1 0 0 1 1 1 0 Solute carrier family 12 Suf PF05843.14 EAQ92856.1 - 5 7.0 22.6 0.058 13.4 11.5 2.3 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DUF913 PF06025.12 EAQ92856.1 - 5.8 5.8 9.1 13 4.6 9.1 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF1980 PF09323.10 EAQ92856.1 - 6.8 6.6 12.5 15 5.4 10.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) FAM91_C PF14648.6 EAQ92856.1 - 6.8 5.4 6.5 10 4.8 6.5 1.1 1 0 0 1 1 1 0 FAM91 C-terminus NARP1 PF12569.8 EAQ92856.1 - 8 5.2 15.1 15 4.4 15.1 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Connexin PF00029.19 EAQ92856.1 - 8.2 6.1 12.2 16 5.1 12.2 1.4 1 0 0 1 1 1 0 Connexin Complex1_49kDa PF00346.19 EAQ92857.1 - 1.3e-122 408.2 0.0 1.7e-122 407.7 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.19 EAQ92857.1 - 0.014 14.3 0.0 0.027 13.4 0.0 1.4 1 1 0 1 1 1 0 Nickel-dependent hydrogenase RNA_pol_A_bac PF01000.26 EAQ92858.1 - 1.7e-26 92.8 0.0 3.8e-26 91.7 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 EAQ92858.1 - 8e-17 60.4 0.0 1.1e-16 60.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Prot_ATP_OB_N PF17758.1 EAQ92858.1 - 0.026 14.2 0.0 0.056 13.1 0.0 1.5 1 0 0 1 1 1 0 Proteasomal ATPase OB N-terminal domain ThiF PF00899.21 EAQ92859.1 - 1.7e-65 220.8 0.0 2.5e-65 220.3 0.0 1.1 1 0 0 1 1 1 1 ThiF family E2_bind PF08825.10 EAQ92859.1 - 1.6e-30 105.1 0.0 2.6e-30 104.4 0.0 1.4 1 0 0 1 1 1 1 E2 binding domain UAE_UbL PF14732.6 EAQ92859.1 - 0.0013 19.3 0.0 0.01 16.4 0.0 2.3 2 0 0 2 2 2 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain Shikimate_DH PF01488.20 EAQ92859.1 - 0.0016 18.5 0.2 0.0045 17.0 0.1 1.7 1 1 1 2 2 2 1 Shikimate / quinate 5-dehydrogenase Ecm33 PF12454.8 EAQ92859.1 - 0.022 14.9 2.6 0.049 13.8 2.6 1.6 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein UDPG_MGDP_dh_N PF03721.14 EAQ92859.1 - 0.031 13.9 0.0 0.048 13.2 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_7 PF13241.6 EAQ92859.1 - 0.037 14.5 0.2 0.085 13.3 0.1 1.7 2 0 0 2 2 2 0 Putative NAD(P)-binding Pyr_redox PF00070.27 EAQ92859.1 - 0.04 14.5 0.0 0.095 13.3 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase UBA_e1_thiolCys PF10585.9 EAQ92859.1 - 0.35 10.8 1.4 10 6.0 0.0 2.2 1 1 1 2 2 2 0 Ubiquitin-activating enzyme active site Telomere_reg-2 PF10193.9 EAQ92860.1 - 2.9e-37 127.4 0.0 1e-36 125.7 0.0 2.0 1 0 0 1 1 1 1 Telomere length regulation protein G-patch PF01585.23 EAQ92863.1 - 1.2e-05 25.1 0.0 6e-05 22.9 0.0 2.4 1 1 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 EAQ92863.1 - 0.0012 18.9 0.1 0.0012 18.9 0.1 4.2 4 1 0 4 4 4 1 G-patch domain TFIIF_alpha PF05793.12 EAQ92863.1 - 0.0027 16.4 42.6 0.0039 15.9 42.6 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) BTB PF00651.31 EAQ92864.1 - 0.14 12.4 0.0 0.33 11.2 0.0 1.6 1 0 0 1 1 1 0 BTB/POZ domain DUF4596 PF15363.6 EAQ92865.1 - 1.4 9.2 5.5 1 9.7 1.4 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4596) RhoGAP PF00620.27 EAQ92866.1 - 2.8e-44 150.6 0.3 1.1e-43 148.7 0.3 2.0 2 0 0 2 2 2 1 RhoGAP domain PH PF00169.29 EAQ92866.1 - 2.2e-12 47.4 0.0 5.7e-12 46.1 0.0 1.8 1 0 0 1 1 1 1 PH domain Fungal_trans PF04082.18 EAQ92866.1 - 0.00061 18.9 0.0 0.0012 18.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EAQ92866.1 - 0.02 15.0 7.9 0.034 14.3 7.9 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain PH_8 PF15409.6 EAQ92866.1 - 0.091 13.0 0.0 0.28 11.5 0.0 1.8 2 0 0 2 2 2 0 Pleckstrin homology domain PITH PF06201.13 EAQ92870.1 - 4.7e-39 134.0 0.0 7.4e-39 133.4 0.0 1.3 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.20 EAQ92870.1 - 1.5e-25 89.1 0.0 2.6e-25 88.4 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EAQ92870.1 - 3.2e-08 34.0 0.2 1e-07 32.4 0.2 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 EAQ92870.1 - 5.4e-07 29.2 0.1 1e-06 28.3 0.1 1.4 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 EAQ92870.1 - 3.8e-06 27.2 0.1 6.4e-05 23.2 0.1 2.3 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.6 EAQ92870.1 - 0.0019 18.0 0.0 0.004 16.9 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 EAQ92870.1 - 0.0035 17.5 0.1 0.0067 16.6 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 EAQ92870.1 - 0.004 17.1 0.2 0.029 14.3 0.2 2.0 1 1 0 1 1 1 1 AhpC/TSA family HyaE PF07449.11 EAQ92870.1 - 0.016 15.1 0.0 0.032 14.2 0.0 1.4 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Redoxin PF08534.10 EAQ92870.1 - 0.025 14.3 0.4 0.43 10.3 0.2 2.2 1 1 1 2 2 2 0 Redoxin DIM1 PF02966.16 EAQ92870.1 - 0.072 12.9 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Mitosis protein DIM1 Serglycin PF04360.12 EAQ92870.1 - 0.1 12.5 1.5 0.19 11.6 1.5 1.4 1 0 0 1 1 1 0 Serglycin Thioredoxin_3 PF13192.6 EAQ92870.1 - 0.15 12.1 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin domain MFS_1 PF07690.16 EAQ92873.1 - 3.1e-27 95.4 37.0 3.1e-27 95.4 37.0 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EAQ92873.1 - 4.3e-13 48.9 1.9 4.3e-13 48.9 1.9 2.2 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 EAQ92873.1 - 0.00022 19.8 2.2 0.0018 16.7 1.4 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF4083 PF13314.6 EAQ92873.1 - 0.2 11.6 2.3 0.95 9.5 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4083) Presenilin PF01080.17 EAQ92874.1 - 1.6 7.4 3.1 2 7.1 3.1 1.1 1 0 0 1 1 1 0 Presenilin PRP38_assoc PF12871.7 EAQ92874.1 - 6.3 7.5 32.7 2.6 8.7 17.2 2.0 2 0 0 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term PRA1 PF03208.19 EAQ92875.1 - 8.3e-27 93.6 1.7 1.2e-26 93.1 1.7 1.2 1 0 0 1 1 1 1 PRA1 family protein GH131_N PF18271.1 EAQ92877.1 - 8.6e-71 238.6 2.3 1.9e-70 237.5 2.3 1.5 1 1 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain FluMu_N PF17891.1 EAQ92877.1 - 0.028 14.2 0.0 0.065 13.0 0.0 1.5 1 0 0 1 1 1 0 Mu-like prophage FluMu N-terminal domain DUF2911 PF11138.8 EAQ92877.1 - 0.037 13.9 0.0 0.055 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2911) YbjQ_1 PF01906.17 EAQ92878.1 - 6e-29 100.8 0.5 7.2e-29 100.5 0.5 1.1 1 0 0 1 1 1 1 Putative heavy-metal-binding DPPIV_N PF00930.21 EAQ92879.1 - 1.7e-110 369.1 0.1 2.3e-110 368.7 0.1 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 EAQ92879.1 - 6.1e-56 189.2 1.8 1.1e-55 188.4 1.8 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 EAQ92879.1 - 4.3e-06 26.5 1.1 6.7e-05 22.6 0.6 2.5 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) PAF-AH_p_II PF03403.13 EAQ92879.1 - 0.048 12.2 0.0 0.084 11.4 0.0 1.3 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Methyltransf_11 PF08241.12 EAQ92880.1 - 8.1e-19 68.1 0.0 2.2e-18 66.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Sterol_MT_C PF08498.10 EAQ92880.1 - 5.9e-18 64.9 0.5 1.2e-17 64.0 0.5 1.5 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_25 PF13649.6 EAQ92880.1 - 2.4e-16 60.2 0.0 4.7e-16 59.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAQ92880.1 - 2.3e-15 56.7 0.0 3.2e-15 56.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EAQ92880.1 - 3.5e-12 46.5 0.0 5.8e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EAQ92880.1 - 2.1e-08 33.8 0.0 2.9e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 EAQ92880.1 - 3.2e-08 33.2 0.0 4.7e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 EAQ92880.1 - 3.2e-08 34.2 0.0 9.7e-08 32.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.19 EAQ92880.1 - 0.0058 16.4 0.0 0.0096 15.7 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.12 EAQ92880.1 - 0.011 15.3 0.0 0.03 13.9 0.0 1.7 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW Methyltransf_9 PF08003.11 EAQ92880.1 - 0.015 14.3 0.0 0.028 13.3 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) Methyltransf_8 PF05148.15 EAQ92880.1 - 0.023 14.5 0.0 0.23 11.3 0.0 2.0 1 1 0 1 1 1 0 Hypothetical methyltransferase Methyltransf_29 PF03141.16 EAQ92880.1 - 0.16 10.5 0.0 0.23 9.9 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_15 PF09445.10 EAQ92880.1 - 0.18 11.4 0.0 0.26 10.8 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase DarT PF14487.6 EAQ92881.1 - 0.05 13.5 0.2 0.076 12.8 0.2 1.2 1 0 0 1 1 1 0 ssDNA thymidine ADP-ribosyltransferase, DarT ATP-synt_ab PF00006.25 EAQ92884.1 - 1.4e-22 80.4 0.1 1.8e-22 80.0 0.1 1.1 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 EAQ92884.1 - 0.00018 21.9 0.3 0.00044 20.7 0.3 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain RbcS PF12338.8 EAQ92884.1 - 0.017 15.3 0.4 0.59 10.4 0.2 2.5 2 0 0 2 2 2 0 Ribulose-1,5-bisphosphate carboxylase small subunit ATP-synt_ab_C PF00306.27 EAQ92885.1 - 2.6e-46 157.1 0.1 2.9e-46 156.9 0.1 1.0 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain Tex_N PF09371.10 EAQ92885.1 - 0.081 12.6 0.0 0.18 11.5 0.0 1.5 2 0 0 2 2 2 0 Tex-like protein N-terminal domain zf-RVT PF13966.6 EAQ92886.1 - 0.11 13.2 0.0 0.35 11.6 0.0 1.8 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase AAA_19 PF13245.6 EAQ92887.1 - 0.019 15.3 0.0 0.021 15.1 0.0 1.1 1 0 0 1 1 1 0 AAA domain Mannosyl_trans3 PF11051.8 EAQ92888.1 - 2.4e-36 125.5 0.1 4.3e-18 65.6 0.0 2.1 1 1 1 2 2 2 2 Mannosyltransferase putative Carb_kinase PF01256.17 EAQ92889.1 - 1.5e-08 34.4 0.0 1.7e-08 34.3 0.0 1.1 1 0 0 1 1 1 1 Carbohydrate kinase Carb_kinase PF01256.17 EAQ92890.1 - 1.6e-11 44.2 0.1 2.1e-11 43.8 0.1 1.1 1 0 0 1 1 1 1 Carbohydrate kinase Ribosomal_L5_C PF00673.21 EAQ92892.1 - 7.6e-22 77.3 0.0 1.1e-21 76.8 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 EAQ92892.1 - 9.4e-19 67.5 0.0 2.7e-18 66.1 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L5 MPC PF03650.13 EAQ92893.1 - 8.5e-34 116.0 0.1 1.5e-33 115.2 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers LSM PF01423.22 EAQ92893.1 - 1.2e-18 66.5 0.0 2e-18 65.9 0.0 1.2 1 0 0 1 1 1 1 LSM domain PYC_OADA PF02436.18 EAQ92894.1 - 1.4e-67 227.3 0.0 2.5e-67 226.5 0.0 1.5 1 0 0 1 1 1 1 Conserved carboxylase domain CPSase_L_D2 PF02786.17 EAQ92894.1 - 5.3e-55 186.2 0.4 4.5e-52 176.6 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain HMGL-like PF00682.19 EAQ92894.1 - 2.3e-25 89.7 0.0 3.9e-25 88.9 0.0 1.3 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.22 EAQ92894.1 - 4.6e-19 68.0 1.5 8.5e-19 67.2 0.6 2.0 2 0 0 2 2 2 1 Biotin-requiring enzyme Biotin_carb_C PF02785.19 EAQ92894.1 - 3.6e-15 56.0 0.0 1.1e-06 28.7 0.0 2.7 2 0 0 2 2 2 2 Biotin carboxylase C-terminal domain Biotin_lipoyl_2 PF13533.6 EAQ92894.1 - 6.9e-10 38.6 0.7 8.3e-06 25.5 0.0 2.8 1 1 1 2 2 2 2 Biotin-lipoyl like HlyD_D23 PF16576.5 EAQ92894.1 - 1.3e-05 24.5 0.1 0.091 12.0 0.0 2.4 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion Dala_Dala_lig_C PF07478.13 EAQ92894.1 - 1.5e-05 24.7 0.0 2.7e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 EAQ92894.1 - 1.9e-05 24.3 0.0 3.6e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_ST PF14397.6 EAQ92894.1 - 0.0027 17.0 0.0 0.011 15.0 0.0 1.9 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp DUF2118 PF09891.9 EAQ92894.1 - 0.0052 16.8 0.1 0.079 12.9 0.1 2.6 2 0 0 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2118) HlyD_3 PF13437.6 EAQ92894.1 - 0.013 16.2 0.8 2.3 8.9 0.1 3.1 4 0 0 4 4 2 0 HlyD family secretion protein GCV_H PF01597.19 EAQ92894.1 - 0.034 14.0 0.5 0.61 10.0 0.1 2.4 1 1 1 2 2 2 0 Glycine cleavage H-protein RimK PF08443.11 EAQ92894.1 - 0.079 12.5 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 RimK-like ATP-grasp domain NQRA PF05896.11 EAQ92894.1 - 0.13 11.7 0.1 0.22 10.9 0.1 1.3 1 0 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) GARS_A PF01071.19 EAQ92894.1 - 0.14 11.9 0.0 0.35 10.6 0.0 1.7 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Clathrin PF00637.20 EAQ92895.1 - 1.7e-196 644.0 32.8 3e-32 111.4 1.8 7.5 7 0 0 7 7 7 7 Region in Clathrin and VPS Clathrin_H_link PF13838.6 EAQ92895.1 - 2.5e-33 113.8 2.6 3.4e-33 113.4 0.8 2.4 2 0 0 2 2 2 1 Clathrin-H-link Clathrin_propel PF01394.20 EAQ92895.1 - 2.4e-32 109.7 0.2 1.6e-06 28.1 0.1 6.6 6 0 0 6 6 6 6 Clathrin propeller repeat TPR_7 PF13176.6 EAQ92895.1 - 0.00059 19.7 3.7 7.9 6.8 0.0 7.2 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_8 PF13181.6 EAQ92895.1 - 0.0058 16.8 1.6 8.9 6.8 0.0 5.6 5 0 0 5 5 5 1 Tetratricopeptide repeat Rop PF01815.16 EAQ92895.1 - 0.028 14.3 0.1 0.12 12.3 0.1 2.1 1 0 0 1 1 1 0 Rop protein Coatomer_WDAD PF04053.14 EAQ92895.1 - 0.031 13.3 5.9 5.6 5.9 0.2 4.3 4 0 0 4 4 4 0 Coatomer WD associated region PPR PF01535.20 EAQ92895.1 - 0.031 14.5 0.2 48 4.5 0.0 5.0 3 0 0 3 3 3 0 PPR repeat Clathrin-link PF09268.10 EAQ92895.1 - 0.034 13.5 0.4 3.5 7.1 0.0 2.7 2 0 0 2 2 2 0 Clathrin, heavy-chain linker TPR_14 PF13428.6 EAQ92895.1 - 0.44 11.5 16.0 3 8.9 0.1 8.2 9 0 0 9 9 9 0 Tetratricopeptide repeat Methyltr_RsmB-F PF01189.17 EAQ92896.1 - 3e-74 249.0 0.0 4.8e-74 248.3 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 EAQ92896.1 - 2.3e-08 34.4 0.1 3e-07 30.8 0.0 2.5 2 0 0 2 2 2 1 N-terminal domain of 16S rRNA methyltransferase RsmF DUF2431 PF10354.9 EAQ92896.1 - 0.031 14.5 0.0 0.13 12.5 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF2431) DUF1640 PF07798.11 EAQ92897.1 - 2.2e-55 187.4 8.9 2.8e-55 187.1 8.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) GNAT_acetyltr_2 PF13718.6 EAQ92897.1 - 0.26 10.6 1.9 0.55 9.6 0.1 2.1 1 1 2 3 3 3 0 GNAT acetyltransferase 2 DUF5374 PF17344.2 EAQ92898.1 - 9.3 6.3 5.7 77 3.3 0.7 3.3 3 0 0 3 3 3 0 Family of unknown function (DUF5374) Rad50_zn_hook PF04423.14 EAQ92900.1 - 0.0054 16.5 1.1 0.5 10.2 0.1 2.5 2 0 0 2 2 2 1 Rad50 zinc hook motif zf-RING_2 PF13639.6 EAQ92900.1 - 0.02 15.2 6.9 0.02 15.2 6.9 3.1 3 1 0 3 3 3 0 Ring finger domain Prok-RING_4 PF14447.6 EAQ92900.1 - 0.021 14.6 3.4 4.6 7.2 0.1 3.2 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 RINGv PF12906.7 EAQ92900.1 - 1.4 9.2 10.0 0.092 12.9 3.2 2.6 2 0 0 2 2 2 0 RING-variant domain zf-RING_11 PF17123.5 EAQ92900.1 - 2 8.2 5.4 2.4 8.0 0.0 2.9 3 0 0 3 3 3 0 RING-like zinc finger zf-C2H2_4 PF13894.6 EAQ92900.1 - 2.6 9.1 6.3 18 6.5 0.3 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger zf-RING_UBOX PF13445.6 EAQ92900.1 - 6.6 6.9 14.9 0.079 13.0 2.1 3.0 3 0 0 3 3 3 0 RING-type zinc-finger zf-RING_4 PF14570.6 EAQ92900.1 - 8.5 6.3 9.8 32 4.4 0.1 3.3 2 1 1 3 3 3 0 RING/Ubox like zinc-binding domain Cullin PF00888.22 EAQ92901.1 - 4.2e-187 623.5 0.6 4.9e-187 623.3 0.6 1.0 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 EAQ92901.1 - 1.6e-12 47.3 0.2 6.9e-12 45.2 0.0 2.2 2 0 0 2 2 2 1 Cullin protein neddylation domain zf-DNL PF05180.12 EAQ92902.1 - 3.8e-28 97.2 0.3 6.5e-28 96.5 0.3 1.4 1 0 0 1 1 1 1 DNL zinc finger HypA PF01155.19 EAQ92902.1 - 0.051 13.6 0.5 0.25 11.4 0.3 1.9 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA TFIIA PF03153.13 EAQ92902.1 - 0.14 12.2 5.6 0.15 12.0 5.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CCDC53 PF10152.9 EAQ92902.1 - 0.61 10.5 5.8 0.84 10.0 5.8 1.2 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex KAR9 PF08580.10 EAQ92902.1 - 0.67 8.4 8.9 0.81 8.1 8.9 1.0 1 0 0 1 1 1 0 Yeast cortical protein KAR9 PAT1 PF09770.9 EAQ92902.1 - 1.2 7.3 5.5 1.4 7.1 5.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4551 PF15087.6 EAQ92902.1 - 1.5 7.5 6.4 1.9 7.3 6.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DRIM PF07539.12 EAQ92903.1 - 1.4e-201 671.1 1.6 1.4e-201 671.1 1.6 2.8 4 0 0 4 4 4 1 Down-regulated in metastasis CobT PF06213.12 EAQ92903.1 - 0.00072 19.0 0.2 0.017 14.5 0.9 2.6 2 0 0 2 2 2 1 Cobalamin biosynthesis protein CobT DUF3161 PF11362.8 EAQ92903.1 - 0.084 12.9 0.0 0.3 11.1 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3161) Rcd1 PF04078.13 EAQ92903.1 - 0.085 12.1 0.5 1.9 7.7 0.0 2.8 2 0 0 2 2 2 0 Cell differentiation family, Rcd1-like HEAT PF02985.22 EAQ92903.1 - 0.11 12.8 2.1 29 5.3 0.0 5.8 6 0 0 6 6 6 0 HEAT repeat Vac14_Fab1_bd PF12755.7 EAQ92903.1 - 0.12 13.0 0.1 4.1 8.1 0.0 3.4 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region DNA_RNApol_7kD PF03604.13 EAQ92904.1 - 2e-06 27.4 0.1 3e-06 26.8 0.1 1.3 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit LacI PF00356.21 EAQ92904.1 - 0.0099 15.7 0.1 0.017 14.9 0.1 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family CwfJ_C_1 PF04677.15 EAQ92905.1 - 8.4e-25 87.0 0.0 2.4e-24 85.6 0.0 1.6 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 EAQ92905.1 - 4.1e-15 56.5 0.8 8.7e-15 55.4 0.8 1.6 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 ERAP1_C PF11838.8 EAQ92906.1 - 1.1e-23 84.3 0.6 6.9e-22 78.4 0.2 2.0 1 1 1 2 2 2 2 ERAP1-like C-terminal domain HEAT_2 PF13646.6 EAQ92906.1 - 0.0071 16.7 0.2 0.026 14.9 0.0 2.0 2 0 0 2 2 2 1 HEAT repeats DUF3364 PF11844.8 EAQ92906.1 - 0.11 12.8 0.1 0.21 11.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3364) Peptidase_M1 PF01433.20 EAQ92907.1 - 1.4e-70 237.2 0.0 2.1e-70 236.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 EAQ92907.1 - 3.6e-11 43.2 0.1 1.8e-08 34.3 0.1 2.5 1 1 1 2 2 2 2 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 EAQ92907.1 - 5.2e-09 36.6 0.0 1.8e-07 31.5 0.0 2.3 1 1 1 2 2 2 1 Peptidase M1 N-terminal domain GATase PF00117.28 EAQ92907.1 - 0.16 11.7 0.0 0.5 10.1 0.0 1.7 2 0 0 2 2 2 0 Glutamine amidotransferase class-I Rhodanese PF00581.20 EAQ92909.1 - 3.7e-12 46.7 0.0 6.7e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain DNA_pol_phi PF04931.13 EAQ92911.1 - 8.6e-186 619.4 17.1 1.4e-185 618.6 17.1 1.3 1 1 0 1 1 1 1 DNA polymerase phi EB1 PF03271.17 EAQ92911.1 - 0.031 14.5 0.1 0.53 10.6 0.0 2.6 2 0 0 2 2 2 0 EB1-like C-terminal motif DUF1676 PF07898.13 EAQ92911.1 - 0.42 10.6 3.1 1.1 9.3 3.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) RRN3 PF05327.11 EAQ92911.1 - 2.1 6.8 8.9 4.6 5.7 8.9 1.6 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Goodbye PF17109.5 EAQ92911.1 - 7.3 7.1 9.0 0.95 9.9 0.3 3.6 4 0 0 4 4 4 0 fungal STAND N-terminal Goodbye domain Proteasome PF00227.26 EAQ92912.1 - 1.2e-27 96.6 0.3 4.3e-13 49.2 0.0 2.2 1 1 1 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.9 EAQ92912.1 - 0.16 11.7 0.4 0.16 11.7 0.4 1.7 2 0 0 2 2 2 0 Proteasome subunit A N-terminal signature DnaJ PF00226.31 EAQ92915.1 - 6e-16 58.3 0.2 9.4e-16 57.7 0.2 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ PF00226.31 EAQ92916.1 - 1.3e-09 38.0 0.4 2.8e-09 37.0 0.4 1.6 1 0 0 1 1 1 1 DnaJ domain DUF5568 PF17724.1 EAQ92916.1 - 0.027 14.3 1.2 0.027 14.3 1.2 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5568) RestrictionSfiI PF11487.8 EAQ92916.1 - 0.068 13.0 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 Type II restriction enzyme SfiI Tyrosinase PF00264.20 EAQ92917.1 - 5.5e-48 164.2 0.0 7.4e-48 163.8 0.0 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase DUF2318 PF10080.9 EAQ92919.1 - 0.022 14.9 1.6 0.022 14.9 1.6 1.9 1 1 1 2 2 2 0 Predicted membrane protein (DUF2318) GFA PF04828.14 EAQ92919.1 - 0.88 10.0 6.9 3.4 8.1 0.1 2.4 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme A2L_zn_ribbon PF08792.10 EAQ92919.1 - 8.9 6.2 10.9 0.34 10.7 4.7 1.8 2 0 0 2 2 2 0 A2L zinc ribbon domain GMC_oxred_N PF00732.19 EAQ92920.1 - 3.9e-33 115.1 0.0 6.3e-33 114.4 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EAQ92920.1 - 2.6e-26 92.9 0.5 6.1e-26 91.7 0.3 1.7 2 0 0 2 2 2 1 GMC oxidoreductase DAO PF01266.24 EAQ92920.1 - 0.005 16.5 0.0 0.019 14.5 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 EAQ92920.1 - 0.017 14.4 0.0 0.028 13.6 0.0 1.2 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.12 EAQ92920.1 - 0.035 13.2 0.0 0.071 12.1 0.0 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein DUF2384 PF09722.10 EAQ92920.1 - 0.089 12.8 0.0 0.32 11.1 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2384) NAD_binding_8 PF13450.6 EAQ92920.1 - 0.097 12.9 0.1 0.28 11.4 0.1 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 EAQ92920.1 - 0.1 11.4 0.0 0.16 10.8 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase TMEM171 PF15471.6 EAQ92920.1 - 0.29 10.1 1.5 0.49 9.3 1.5 1.2 1 0 0 1 1 1 0 Transmembrane protein family 171 Zn_clus PF00172.18 EAQ92921.1 - 4.3e-07 29.9 6.8 1e-06 28.8 6.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EAQ92921.1 - 0.0049 15.7 0.9 0.0065 15.3 0.9 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF4231 PF14015.6 EAQ92925.1 - 0.03 14.8 0.2 0.042 14.3 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) Peptidase_M56 PF05569.11 EAQ92925.1 - 0.056 12.6 0.5 0.069 12.3 0.5 1.1 1 0 0 1 1 1 0 BlaR1 peptidase M56 hDGE_amylase PF14701.6 EAQ92926.1 - 1.2e-178 594.8 0.0 1.5e-178 594.4 0.0 1.1 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain GDE_C PF06202.14 EAQ92926.1 - 5.2e-119 397.6 0.0 1.1e-118 396.5 0.0 1.5 2 0 0 2 2 2 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.6 EAQ92926.1 - 1.7e-87 293.3 0.0 5.4e-87 291.7 0.0 1.9 3 0 0 3 3 3 1 Central domain of human glycogen debranching enzyme hGDE_N PF14699.6 EAQ92926.1 - 6.1e-30 103.2 0.0 1.3e-29 102.2 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme NAD_Gly3P_dh_N PF01210.23 EAQ92927.1 - 2e-45 154.6 0.1 3.5e-45 153.8 0.1 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 EAQ92927.1 - 1.2e-35 122.8 0.0 2.2e-35 122.0 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus AIG2_2 PF13772.6 EAQ92928.1 - 5.6e-06 26.7 0.1 9.3e-05 22.8 0.1 2.2 2 0 0 2 2 2 1 AIG2-like family Death PF00531.22 EAQ92929.1 - 0.032 14.4 0.1 0.1 12.8 0.1 1.9 1 1 0 1 1 1 0 Death domain Peptidase_C48 PF02902.19 EAQ92930.1 - 2.7e-14 53.5 0.1 1.5e-13 51.1 0.1 2.1 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain SLX9 PF15341.6 EAQ92931.1 - 3.2e-44 150.5 2.5 5.1e-44 149.8 2.5 1.3 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 LSM_int_assoc PF16605.5 EAQ92931.1 - 0.0054 16.8 1.6 0.014 15.5 1.6 1.7 1 0 0 1 1 1 1 LSM-interacting associated unstructured ThiF PF00899.21 EAQ92932.1 - 3.4e-53 180.5 0.0 4.8e-53 180.0 0.0 1.1 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 EAQ92932.1 - 1.7e-10 41.4 0.0 1e-09 38.9 0.0 2.2 2 0 0 2 2 2 1 Rhodanese-like domain Shikimate_DH PF01488.20 EAQ92932.1 - 0.00024 21.2 0.2 0.00063 19.8 0.1 1.8 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 EAQ92932.1 - 0.011 16.2 0.0 0.025 15.0 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding FAD_binding_3 PF01494.19 EAQ92932.1 - 0.49 9.6 1.3 2.6 7.2 1.6 1.9 2 0 0 2 2 2 0 FAD binding domain Sacchrp_dh_NADP PF03435.18 EAQ92932.1 - 0.63 10.3 1.9 8.4 6.7 1.7 2.6 2 1 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Pam17 PF08566.10 EAQ92933.1 - 2.8e-64 215.9 0.0 4.1e-64 215.4 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 Chromo PF00385.24 EAQ92934.1 - 4.3e-09 36.1 3.9 1.1e-08 34.8 3.9 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DHDPS PF00701.22 EAQ92935.1 - 3.6e-40 137.5 0.0 5e-40 137.0 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family PIF1 PF05970.14 EAQ92937.1 - 1.9e-07 30.6 0.1 2.3e-07 30.3 0.1 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 EAQ92937.1 - 0.058 13.1 0.1 0.086 12.5 0.1 1.2 1 0 0 1 1 1 0 AAA domain ydhR PF08803.11 EAQ92937.1 - 0.19 11.7 0.1 0.32 10.9 0.1 1.4 1 0 0 1 1 1 0 Putative mono-oxygenase ydhR MFS_1 PF07690.16 EAQ92939.1 - 2.3e-18 66.3 35.1 7.7e-15 54.7 22.7 3.8 2 2 1 3 3 3 3 Major Facilitator Superfamily DUF3237 PF11578.8 EAQ92941.1 - 4.8e-35 120.6 0.0 6.6e-35 120.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) zf-BED PF02892.15 EAQ92941.1 - 0.006 16.6 4.2 0.75 9.9 0.3 2.4 2 0 0 2 2 2 2 BED zinc finger PHD_4 PF16866.5 EAQ92941.1 - 0.28 11.3 4.7 6.8 6.9 0.4 2.5 2 0 0 2 2 2 0 PHD-finger Zn_Tnp_IS91 PF14319.6 EAQ92941.1 - 7.6 6.6 12.5 13 6.0 3.7 2.3 2 0 0 2 2 2 0 Transposase zinc-binding domain HLH PF00010.26 EAQ92943.1 - 9.8e-11 41.4 0.0 3.5e-10 39.7 0.0 2.0 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain SPX PF03105.19 EAQ92943.1 - 8.4 6.2 11.4 16 5.3 11.4 1.5 1 0 0 1 1 1 0 SPX domain NAD_binding_10 PF13460.6 EAQ92945.1 - 0.0001 22.3 0.0 0.00011 22.2 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding DapB_N PF01113.20 EAQ92945.1 - 0.00064 19.8 0.0 0.00086 19.4 0.0 1.4 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Epimerase PF01370.21 EAQ92945.1 - 0.0011 18.4 0.0 0.0011 18.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EAQ92945.1 - 0.0023 17.1 0.0 0.0031 16.7 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.13 EAQ92945.1 - 0.003 17.2 0.0 0.007 16.0 0.0 1.6 1 1 1 2 2 2 1 NmrA-like family 3Beta_HSD PF01073.19 EAQ92945.1 - 0.18 10.8 0.0 0.2 10.6 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF3439 PF11921.8 EAQ92946.1 - 2.5 8.1 9.4 4.5 7.3 9.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) DUF1770 PF08589.10 EAQ92947.1 - 0.11 13.5 0.6 0.11 13.5 0.6 3.1 2 1 0 2 2 2 0 Fungal protein of unknown function (DUF1770) Rrn6 PF10214.9 EAQ92949.1 - 0.41 9.1 2.2 0.48 8.9 2.2 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DUF4360 PF14273.6 EAQ92950.1 - 1e-26 93.9 1.6 1.3e-26 93.6 1.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Form_Nir_trans PF01226.17 EAQ92951.1 - 4.6e-26 91.6 8.5 5.2e-19 68.5 9.6 2.0 1 1 1 2 2 2 2 Formate/nitrite transporter Cellulase PF00150.18 EAQ92953.1 - 4.7e-50 170.6 3.9 6e-50 170.3 3.9 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.18 EAQ92953.1 - 1.1e-11 44.5 16.9 1.1e-11 44.5 16.9 2.6 2 0 0 2 2 2 1 Fungal cellulose binding domain CHASE4 PF05228.13 EAQ92953.1 - 0.0059 16.8 0.0 0.016 15.4 0.0 1.7 1 1 1 2 2 2 1 CHASE4 domain Toxin_7 PF05980.12 EAQ92953.1 - 7.3 6.9 6.7 0.97 9.7 0.4 2.5 3 0 0 3 3 3 0 Toxin 7 DUF3243 PF11588.8 EAQ92954.1 - 0.012 15.8 0.1 0.033 14.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3243) Cid2 PF09774.9 EAQ92954.1 - 0.65 10.4 4.9 0.99 9.8 4.9 1.2 1 0 0 1 1 1 0 Caffeine-induced death protein 2 HAUS6_N PF14661.6 EAQ92954.1 - 0.91 9.1 4.0 1.3 8.6 4.0 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Glyco_hydro_61 PF03443.14 EAQ92956.1 - 4.3e-54 183.6 0.5 5.6e-54 183.2 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Amidoligase_2 PF12224.8 EAQ92958.1 - 6.9e-13 48.8 0.0 1.2e-12 48.0 0.0 1.3 1 0 0 1 1 1 1 Putative amidoligase enzyme DUF4719 PF15843.5 EAQ92958.1 - 0.49 10.5 3.7 0.82 9.8 3.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4719) AA_permease_2 PF13520.6 EAQ92961.1 - 7.8e-58 196.3 41.1 9.3e-58 196.0 41.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EAQ92961.1 - 4.2e-18 65.2 35.8 6.4e-18 64.6 35.8 1.2 1 0 0 1 1 1 1 Amino acid permease Myb_DNA-binding PF00249.31 EAQ92963.1 - 0.012 15.8 3.9 0.05 13.8 0.6 3.1 3 1 0 3 3 3 0 Myb-like DNA-binding domain zf-C2H2 PF00096.26 EAQ92967.1 - 4.9e-05 23.6 2.7 0.047 14.2 0.2 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EAQ92967.1 - 0.00065 20.3 3.1 0.58 11.1 0.1 3.4 2 0 0 2 2 2 2 C2H2-type zinc finger AFT PF08731.11 EAQ92967.1 - 0.074 13.5 0.1 0.19 12.2 0.1 1.6 1 0 0 1 1 1 0 Transcription factor AFT RVT_1 PF00078.27 EAQ92968.1 - 4.4e-15 55.8 0.0 6.3e-15 55.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 EAQ92968.1 - 0.13 12.9 0.0 0.28 11.9 0.0 1.5 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase RRM_1 PF00076.22 EAQ92969.1 - 1.3e-16 60.1 0.0 3.8e-16 58.7 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ecm29 PF13001.7 EAQ92972.1 - 3.5e-92 309.6 0.0 6.3e-91 305.5 0.0 2.8 3 0 0 3 3 3 1 Proteasome stabiliser HEAT PF02985.22 EAQ92972.1 - 0.0088 16.2 7.2 0.71 10.3 0.0 6.6 6 0 0 6 6 6 1 HEAT repeat IFRD PF05004.13 EAQ92972.1 - 0.011 14.9 5.5 0.76 8.8 0.1 3.1 2 1 0 3 3 3 0 Interferon-related developmental regulator (IFRD) Vac14_Fab1_bd PF12755.7 EAQ92972.1 - 0.098 13.3 0.7 0.99 10.1 0.0 3.0 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 EAQ92972.1 - 0.62 10.6 15.1 10 6.8 0.0 6.6 7 0 0 7 7 7 0 HEAT-like repeat Thioredoxin_7 PF13899.6 EAQ92973.1 - 2.1e-18 66.3 0.1 4.4e-18 65.3 0.1 1.5 1 0 0 1 1 1 1 Thioredoxin-like UBA_4 PF14555.6 EAQ92973.1 - 1.7e-08 34.1 0.2 3.5e-08 33.1 0.2 1.5 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.20 EAQ92973.1 - 4.1e-07 30.1 0.0 8e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 UBX domain Thioredox_DsbH PF03190.15 EAQ92973.1 - 0.072 13.0 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF255 Pkinase PF00069.25 EAQ92974.1 - 1.4e-58 198.3 0.0 4.4e-58 196.7 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ92974.1 - 2.2e-41 141.9 0.0 6.1e-41 140.4 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Nucleoporin_N PF08801.11 EAQ92975.1 - 0.056 12.2 0.2 0.09 11.5 0.2 1.3 1 1 0 1 1 1 0 Nup133 N terminal like Iso_dh PF00180.20 EAQ92977.1 - 1.1e-66 225.4 0.0 1.3e-50 172.6 0.0 2.0 2 0 0 2 2 2 2 Isocitrate/isopropylmalate dehydrogenase Tyosinase_C PF18132.1 EAQ92978.1 - 0.00016 22.3 0.0 0.00086 20.0 0.0 2.0 1 1 0 1 1 1 1 Tyosinase C-terminal domain WBS_methylT PF12589.8 EAQ92979.1 - 1.5e-14 54.5 4.1 2.6e-14 53.7 4.1 1.4 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.12 EAQ92979.1 - 1.8e-10 41.4 0.0 3.8e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAQ92979.1 - 2.5e-09 37.7 0.0 7.3e-09 36.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.19 EAQ92979.1 - 5.5e-05 23.0 0.0 9.5e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.12 EAQ92979.1 - 0.00019 22.1 0.1 0.0011 19.6 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAQ92979.1 - 0.0044 16.8 0.0 0.0069 16.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EAQ92979.1 - 0.0062 15.9 0.0 0.13 11.5 0.0 2.0 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 EAQ92979.1 - 0.049 13.5 0.0 0.077 12.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Serglycin PF04360.12 EAQ92980.1 - 0.0076 16.2 2.4 0.012 15.6 2.4 1.4 1 0 0 1 1 1 1 Serglycin FMO-like PF00743.19 EAQ92982.1 - 5e-18 64.8 0.0 1.1e-16 60.4 0.0 2.0 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 EAQ92982.1 - 5.2e-11 42.3 0.0 6.8e-10 38.6 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EAQ92982.1 - 7.2e-09 35.8 0.1 1.2e-07 31.8 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EAQ92982.1 - 1.7e-08 34.6 0.1 1.1e-07 32.0 0.0 2.4 2 1 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 EAQ92982.1 - 1.2e-07 31.4 0.0 5.1e-06 26.0 0.0 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EAQ92982.1 - 5.8e-06 25.7 0.0 0.00013 21.3 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 EAQ92982.1 - 5.3e-05 23.0 0.0 0.00018 21.2 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EAQ92982.1 - 0.0061 17.1 0.1 2.5 8.7 0.2 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EAQ92982.1 - 0.037 12.7 0.0 0.085 11.5 0.0 1.6 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.17 EAQ92982.1 - 0.042 13.1 0.0 0.083 12.1 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Amino_oxidase PF01593.24 EAQ92982.1 - 0.044 13.1 0.0 0.14 11.4 0.0 1.8 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.19 EAQ92982.1 - 0.058 12.6 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain MFS_1 PF07690.16 EAQ92983.1 - 1.8e-33 115.9 33.0 2.2e-33 115.7 31.9 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily 2-Hacid_dh PF00389.30 EAQ92985.1 - 7.2e-29 100.1 0.1 1.1e-28 99.5 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 2-Hacid_dh_C PF02826.19 EAQ92985.1 - 7e-13 48.3 0.0 1.4e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain LIFR_D2 PF17971.1 EAQ92985.1 - 0.0086 16.3 0.0 0.017 15.3 0.0 1.4 1 0 0 1 1 1 1 Leukemia inhibitory factor receptor D2 domain Dynamin_N PF00350.23 EAQ92986.1 - 1.6e-30 106.4 0.0 4.5e-30 104.9 0.0 1.8 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 EAQ92986.1 - 1.7e-13 50.4 0.0 2.5e-12 46.6 0.0 2.5 2 1 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.23 EAQ92986.1 - 4.6e-05 23.5 0.0 0.00012 22.1 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Phe_tRNA-synt_N PF02912.18 EAQ92986.1 - 0.0088 16.0 0.0 0.038 13.9 0.0 2.1 2 0 0 2 2 2 1 Aminoacyl tRNA synthetase class II, N-terminal domain ABC_tran PF00005.27 EAQ92986.1 - 0.019 15.5 0.0 0.067 13.7 0.0 1.9 1 0 0 1 1 1 0 ABC transporter T3SS_needle_E PF08988.10 EAQ92986.1 - 0.059 13.5 3.0 5.2 7.3 0.1 2.9 2 0 0 2 2 2 0 Type III secretion system, cytoplasmic E component of needle GED PF02212.18 EAQ92986.1 - 0.19 11.9 0.8 0.83 9.9 0.8 2.1 1 0 0 1 1 1 0 Dynamin GTPase effector domain Metal_resist PF13801.6 EAQ92986.1 - 0.2 11.9 0.1 0.2 11.9 0.1 3.9 5 0 0 5 5 5 0 Heavy-metal resistance Pneumo_att_G PF05539.11 EAQ92986.1 - 4 6.9 5.2 6.9 6.2 5.2 1.3 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Ank_4 PF13637.6 EAQ92987.1 - 1.7e-22 79.5 0.8 0.013 16.1 0.0 8.7 7 2 1 9 9 9 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAQ92987.1 - 5e-18 65.5 0.0 3e-06 27.7 0.0 5.9 3 2 3 6 6 6 3 Ankyrin repeats (3 copies) Ank PF00023.30 EAQ92987.1 - 2.2e-17 62.6 11.1 0.018 15.5 0.0 8.7 9 0 0 9 9 9 6 Ankyrin repeat Ank_5 PF13857.6 EAQ92987.1 - 7.8e-11 42.0 4.2 2 8.8 0.0 7.9 8 1 1 9 9 9 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAQ92987.1 - 5.5e-10 38.6 8.8 0.88 10.3 0.0 9.1 10 2 0 10 10 10 4 Ankyrin repeat DUF2520 PF10728.9 EAQ92987.1 - 0.0072 16.1 0.3 0.5 10.1 0.2 2.9 1 1 2 3 3 3 1 Domain of unknown function (DUF2520) Clp_N PF02861.20 EAQ92987.1 - 0.053 13.7 3.8 16 5.7 0.0 4.4 5 0 0 5 5 5 0 Clp amino terminal domain, pathogenicity island component Ank_4 PF13637.6 EAQ92988.1 - 4.1e-52 173.9 11.6 3.8e-07 30.5 0.0 14.1 10 2 4 14 14 14 12 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAQ92988.1 - 4.1e-52 174.7 1.1 3.6e-11 43.5 0.0 9.3 4 3 6 10 10 10 9 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAQ92988.1 - 2.4e-43 145.6 16.6 3.7e-05 23.9 0.0 14.6 10 6 4 14 14 14 10 Ankyrin repeats (many copies) Ank PF00023.30 EAQ92988.1 - 4.2e-43 144.0 33.2 1.9e-06 28.0 0.2 14.9 15 0 0 15 15 15 10 Ankyrin repeat Ank_3 PF13606.6 EAQ92988.1 - 2.2e-34 113.6 11.9 0.00029 21.1 0.0 15.1 17 0 0 17 17 17 7 Ankyrin repeat NACHT PF05729.12 EAQ92988.1 - 2.9e-05 24.0 0.0 9.2e-05 22.4 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EAQ92988.1 - 0.0032 17.9 0.0 0.017 15.5 0.0 2.2 1 0 0 1 1 1 1 AAA ATPase domain RSN1_7TM PF02714.15 EAQ92991.1 - 6.1e-80 268.5 20.2 8.8e-80 267.9 20.2 1.2 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 EAQ92991.1 - 2.2e-39 135.5 0.0 4.3e-39 134.6 0.0 1.5 1 1 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 EAQ92991.1 - 3.7e-37 127.5 1.6 3.7e-37 127.5 1.6 2.7 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport MutS_V PF00488.21 EAQ92992.1 - 1.7e-58 197.8 0.1 2.8e-58 197.0 0.1 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EAQ92992.1 - 2.4e-29 102.9 1.5 4.6e-29 102.0 1.5 1.5 1 0 0 1 1 1 1 MutS domain III MutS_II PF05188.17 EAQ92992.1 - 0.072 13.4 0.5 0.44 10.8 0.3 2.5 2 1 0 2 2 2 0 MutS domain II Aminotran_4 PF01063.19 EAQ92993.1 - 4.7e-21 75.7 0.0 8.2e-21 74.9 0.0 1.4 1 1 0 1 1 1 1 Amino-transferase class IV DUF4222 PF13973.6 EAQ92993.1 - 0.0096 15.5 0.0 2.4 7.8 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4222) Glyco_transf_20 PF00982.21 EAQ92994.1 - 8.6e-165 549.0 0.2 1.4e-164 548.3 0.2 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 EAQ92994.1 - 2.6e-33 115.1 0.0 5.1e-33 114.2 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase Zincin_2 PF10103.9 EAQ92994.1 - 0.02 14.2 0.0 0.048 12.9 0.0 1.6 1 0 0 1 1 1 0 Zincin-like metallopeptidase Glyco_transf_5 PF08323.11 EAQ92994.1 - 0.078 12.7 0.4 0.17 11.5 0.4 1.5 1 0 0 1 1 1 0 Starch synthase catalytic domain HNH_repeat PF18780.1 EAQ92994.1 - 0.11 12.4 1.8 0.26 11.1 1.8 1.6 1 0 0 1 1 1 0 Homing endonuclease repeat WD40 PF00400.32 EAQ92995.1 - 1.7e-58 193.2 35.6 6.4e-11 42.6 0.7 9.1 8 1 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAQ92995.1 - 2.2e-23 82.3 6.0 0.00045 20.4 0.0 6.5 3 3 3 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EAQ92995.1 - 2.3e-07 30.9 0.3 0.00023 21.1 0.0 3.1 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 EAQ92995.1 - 7.7e-05 21.8 0.0 0.53 9.2 0.0 3.7 3 1 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EAQ92995.1 - 0.00017 20.4 0.5 5 5.6 0.1 4.4 4 1 0 4 4 4 2 Nucleoporin Nup120/160 PD40 PF07676.12 EAQ92995.1 - 0.022 14.7 0.8 6 6.9 0.0 3.9 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat WD40_like PF17005.5 EAQ92995.1 - 0.038 13.3 0.0 9.1 5.5 0.0 3.7 4 1 1 5 5 5 0 WD40-like domain NLE PF08154.12 EAQ92995.1 - 0.11 13.1 0.0 0.2 12.2 0.0 1.4 1 0 0 1 1 1 0 NLE (NUC135) domain FAD_binding_9 PF08021.11 EAQ92995.1 - 0.13 12.5 0.0 0.66 10.2 0.0 2.2 3 0 0 3 3 3 0 Siderophore-interacting FAD-binding domain IKI3 PF04762.12 EAQ92995.1 - 0.24 9.4 0.3 0.74 7.7 0.1 1.8 2 0 0 2 2 2 0 IKI3 family DUF1707 PF08044.11 EAQ92996.1 - 0.062 13.4 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1707) Calc_CGRP_IAPP PF00214.19 EAQ92997.1 - 0.14 12.5 0.2 0.32 11.4 0.1 1.6 1 1 0 1 1 1 0 Calcitonin / CGRP / IAPP family DUF2273 PF10031.9 EAQ92997.1 - 5.2 7.2 6.9 24 5.0 0.1 2.3 2 0 0 2 2 2 0 Small integral membrane protein (DUF2273) Amino_oxidase PF01593.24 EAQ92998.1 - 3.6e-28 99.1 0.0 5.1e-28 98.6 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EAQ92998.1 - 0.0005 20.2 0.0 0.0012 19.0 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain TPP_enzyme_N PF02776.18 EAQ92999.1 - 3.6e-45 153.6 0.0 1.6e-44 151.5 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 EAQ92999.1 - 9.7e-17 61.2 0.2 7.6e-16 58.3 0.0 2.5 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 EAQ92999.1 - 1.6e-14 53.8 0.0 2.5e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain Exo_endo_phos_2 PF14529.6 EAQ93000.1 - 7e-12 45.2 0.0 4.2e-11 42.7 0.0 2.3 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase zf-CCHC PF00098.23 EAQ93000.1 - 0.001 19.0 1.7 0.001 19.0 1.7 2.6 2 0 0 2 2 1 1 Zinc knuckle SlyX PF04102.12 EAQ93000.1 - 0.017 15.8 9.5 0.051 14.2 6.5 3.1 2 1 0 2 2 1 0 SlyX USP8_interact PF08941.10 EAQ93000.1 - 0.018 14.8 0.1 0.067 13.0 0.1 2.0 1 0 0 1 1 1 0 USP8 interacting CorA PF01544.18 EAQ93000.1 - 0.028 13.7 1.4 0.055 12.8 1.4 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein HMMR_N PF15905.5 EAQ93000.1 - 0.028 13.9 0.4 0.05 13.1 0.4 1.3 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal PKcGMP_CC PF16808.5 EAQ93000.1 - 0.046 13.6 0.5 0.14 12.0 0.5 1.9 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Spc29 PF17082.5 EAQ93000.1 - 0.059 13.2 0.2 0.11 12.4 0.2 1.4 1 0 0 1 1 1 0 Spindle Pole Component 29 ZapA PF05164.13 EAQ93000.1 - 0.061 13.8 0.2 1.4 9.4 0.0 2.7 2 0 0 2 2 2 0 Cell division protein ZapA Fib_alpha PF08702.10 EAQ93000.1 - 0.071 13.3 1.2 0.21 11.8 1.2 1.9 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF3584 PF12128.8 EAQ93000.1 - 0.11 10.0 4.6 0.16 9.5 4.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Exo_endo_phos PF03372.23 EAQ93000.1 - 0.12 11.9 0.0 0.25 10.8 0.0 1.5 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family DUF724 PF05266.14 EAQ93000.1 - 0.14 12.0 0.5 0.27 11.1 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) BLOC1_2 PF10046.9 EAQ93000.1 - 0.28 11.5 1.2 0.83 10.0 1.2 1.8 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Exonuc_VII_L PF02601.15 EAQ93000.1 - 0.31 10.6 4.5 0.53 9.8 4.5 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit XPC-binding PF09280.11 EAQ93000.1 - 0.33 10.7 2.4 8.1 6.3 0.5 2.5 1 1 1 2 2 2 0 XPC-binding domain UPF0242 PF06785.11 EAQ93000.1 - 0.45 10.6 3.4 1.1 9.4 3.0 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus YlqD PF11068.8 EAQ93000.1 - 0.46 10.9 4.0 1.2 9.5 4.0 1.7 1 0 0 1 1 1 0 YlqD protein DUF2968 PF11180.8 EAQ93000.1 - 0.77 9.4 6.4 1.7 8.2 6.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) CENP-F_leu_zip PF10473.9 EAQ93000.1 - 5.9 6.9 8.9 0.93 9.5 4.2 2.1 2 1 0 2 2 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Pox_A3L PF05288.11 EAQ93000.1 - 8.9 6.4 6.6 11 6.1 2.5 2.7 2 1 0 2 2 2 0 Poxvirus A3L Protein DNase_NucA_NucB PF14040.6 EAQ93001.1 - 7.4e-07 29.6 0.0 1.5e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 Deoxyribonuclease NucA/NucB Zn_clus PF00172.18 EAQ93002.1 - 0.00064 19.8 6.7 0.0013 18.8 6.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HTH_psq PF05225.16 EAQ93003.1 - 1.7e-05 24.4 0.1 3.7e-05 23.4 0.1 1.6 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.16 EAQ93003.1 - 0.00093 19.2 0.0 0.002 18.1 0.0 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain BrkDBD PF09607.10 EAQ93003.1 - 0.13 12.0 0.1 0.28 11.0 0.1 1.6 1 0 0 1 1 1 0 Brinker DNA-binding domain Condensation PF00668.20 EAQ93004.1 - 4e-65 220.3 0.0 7.4e-65 219.4 0.0 1.3 1 0 0 1 1 1 1 Condensation domain KR PF08659.10 EAQ93004.1 - 2e-52 177.7 0.0 4.4e-51 173.4 0.0 2.7 2 0 0 2 2 2 1 KR domain PS-DH PF14765.6 EAQ93004.1 - 2.2e-50 171.6 0.0 5.2e-50 170.4 0.0 1.6 1 0 0 1 1 1 1 Polyketide synthase dehydratase AMP-binding PF00501.28 EAQ93004.1 - 2.2e-49 168.2 0.0 6.2e-31 107.4 0.0 2.2 1 1 1 2 2 2 2 AMP-binding enzyme NAD_binding_4 PF07993.12 EAQ93004.1 - 8.8e-39 133.2 0.0 4.5e-38 130.9 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein Acyl_transf_1 PF00698.21 EAQ93004.1 - 3.7e-37 128.5 1.5 8.6e-37 127.3 1.5 1.5 1 0 0 1 1 1 1 Acyl transferase domain ketoacyl-synt PF00109.26 EAQ93004.1 - 5.8e-33 114.5 0.4 1.4e-32 113.2 0.4 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EAQ93004.1 - 2.3e-30 105.0 0.0 1.2e-29 102.7 0.0 2.4 2 0 0 2 2 1 1 Beta-ketoacyl synthase, C-terminal domain MULE PF10551.9 EAQ93004.1 - 9.2e-24 83.7 0.4 2.3e-23 82.4 0.4 1.8 1 0 0 1 1 1 1 MULE transposase domain Methyltransf_12 PF08242.12 EAQ93004.1 - 1.6e-17 64.0 0.0 6.8e-17 62.0 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 EAQ93004.1 - 9.4e-17 61.1 3.0 1.3e-08 35.1 0.1 2.9 2 0 0 2 2 2 2 Phosphopantetheine attachment site Epimerase PF01370.21 EAQ93004.1 - 8.9e-15 54.8 0.0 5.2e-13 49.0 0.0 2.4 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Methyltransf_25 PF13649.6 EAQ93004.1 - 3.4e-13 50.1 0.0 2.6e-12 47.3 0.0 2.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EAQ93004.1 - 4.6e-13 49.6 0.0 2e-12 47.6 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 EAQ93004.1 - 8.2e-13 48.2 0.0 3.9e-12 46.0 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase KAsynt_C_assoc PF16197.5 EAQ93004.1 - 1.3e-12 48.1 0.0 6e-12 46.0 0.0 2.2 2 0 0 2 2 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_31 PF13847.6 EAQ93004.1 - 1.6e-12 47.5 0.0 3.7e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EAQ93004.1 - 1.9e-11 44.1 0.0 5.4e-11 42.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain NAD_binding_10 PF13460.6 EAQ93004.1 - 4e-08 33.3 0.1 1.6e-07 31.4 0.1 2.1 1 0 0 1 1 1 1 NAD(P)H-binding Transposase_mut PF00872.18 EAQ93004.1 - 1.9e-06 27.0 0.2 6.7e-06 25.2 0.0 1.8 2 0 0 2 2 2 1 Transposase, Mutator family Methyltransf_16 PF10294.9 EAQ93004.1 - 1e-05 25.3 0.0 2.9e-05 23.9 0.0 1.7 2 0 0 2 2 1 1 Lysine methyltransferase 3Beta_HSD PF01073.19 EAQ93004.1 - 2.4e-05 23.5 0.0 0.0015 17.6 0.0 2.4 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family AMP-binding_C PF13193.6 EAQ93004.1 - 8.7e-05 23.4 0.9 0.00035 21.5 0.0 2.6 2 0 0 2 2 1 1 AMP-binding enzyme C-terminal domain Ubie_methyltran PF01209.18 EAQ93004.1 - 9.6e-05 21.8 0.0 0.0002 20.7 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Thiolase_N PF00108.23 EAQ93004.1 - 0.0011 18.5 0.0 0.0022 17.4 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain DUF2857 PF11198.8 EAQ93004.1 - 0.0017 18.1 0.0 0.0043 16.8 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2857) RrnaAD PF00398.20 EAQ93004.1 - 0.0073 15.4 0.2 3.5 6.6 0.0 2.5 2 0 0 2 2 2 2 Ribosomal RNA adenine dimethylase GDP_Man_Dehyd PF16363.5 EAQ93004.1 - 0.0085 15.5 0.0 0.029 13.8 0.0 1.9 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Methyltransf_33 PF10017.9 EAQ93004.1 - 0.1 11.8 0.0 0.25 10.5 0.0 1.6 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent HSBP1 PF06825.12 EAQ93004.1 - 0.15 12.0 0.0 0.55 10.1 0.0 2.0 1 0 0 1 1 1 0 Heat shock factor binding protein 1 ADH_zinc_N PF00107.26 EAQ93005.1 - 7.9e-07 29.1 0.0 1.4e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EAQ93005.1 - 0.1 13.6 0.0 0.26 12.3 0.0 1.7 1 1 0 1 1 1 0 Zinc-binding dehydrogenase p450 PF00067.22 EAQ93007.1 - 5.2e-31 107.9 0.0 7.4e-31 107.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_4 PF01565.23 EAQ93007.1 - 3.5e-16 59.2 0.1 6.9e-16 58.2 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EAQ93007.1 - 1.3e-06 28.4 0.0 3.7e-06 26.9 0.0 1.8 1 0 0 1 1 1 1 Berberine and berberine like His_Phos_1 PF00300.22 EAQ93007.1 - 0.058 13.1 0.1 0.12 12.0 0.1 1.5 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) p450 PF00067.22 EAQ93008.1 - 2.1e-32 112.5 0.0 2.3e-32 112.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.25 EAQ93010.1 - 1.4e-18 67.1 0.1 1.7e-16 60.3 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EAQ93010.1 - 5e-12 45.9 0.0 2.2e-10 40.5 0.0 2.1 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EAQ93010.1 - 5.8e-05 23.1 0.0 9.7e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF1270 PF06900.11 EAQ93010.1 - 0.097 13.1 0.4 2.6 8.5 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1270) Abhydrolase_6 PF12697.7 EAQ93011.1 - 4.8e-07 30.6 1.1 4.8e-07 30.6 1.1 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF1100 PF06500.11 EAQ93011.1 - 1.8e-05 23.8 0.0 2.6e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_3 PF07859.13 EAQ93011.1 - 0.0066 16.3 0.0 0.018 14.9 0.0 1.7 1 0 0 1 1 1 1 alpha/beta hydrolase fold AXE1 PF05448.12 EAQ93011.1 - 0.02 13.6 0.0 0.038 12.7 0.0 1.4 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.21 EAQ93011.1 - 0.028 13.9 0.0 0.078 12.4 0.0 1.7 2 0 0 2 2 2 0 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 EAQ93011.1 - 0.055 12.7 0.0 0.32 10.2 0.0 2.0 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Esterase PF00756.20 EAQ93011.1 - 0.1 12.2 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Putative esterase UvrD_C_2 PF13538.6 EAQ93012.1 - 0.12 12.2 0.0 0.65 9.9 0.0 2.2 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain Sugar_tr PF00083.24 EAQ93013.1 - 6.3e-79 265.9 20.7 7.4e-79 265.7 20.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EAQ93013.1 - 1.3e-28 100.0 25.2 1e-27 97.0 14.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 EAQ93013.1 - 0.0011 18.4 3.1 0.0011 18.4 3.1 2.4 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB MFS_3 PF05977.13 EAQ93013.1 - 0.051 12.0 5.5 0.068 11.6 1.7 2.1 2 0 0 2 2 2 0 Transmembrane secretion effector Phage_holin_3_2 PF04550.12 EAQ93013.1 - 0.061 13.9 0.4 0.061 13.9 0.4 2.2 3 0 0 3 3 3 0 Phage holin family 2 AA_permease_2 PF13520.6 EAQ93014.1 - 6.9e-58 196.5 27.3 9.1e-58 196.1 27.3 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EAQ93014.1 - 2e-15 56.4 35.2 1.6e-14 53.4 35.2 2.0 1 1 0 1 1 1 1 Amino acid permease ECH_1 PF00378.20 EAQ93014.1 - 0.048 13.0 0.1 13 5.0 0.0 2.6 3 0 0 3 3 3 0 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EAQ93014.1 - 0.24 10.9 0.0 0.85 9.1 0.1 1.8 2 0 0 2 2 2 0 Enoyl-CoA hydratase/isomerase DUF2205 PF10224.9 EAQ93015.1 - 3.6e-12 46.1 0.4 6.5e-12 45.3 0.4 1.5 1 0 0 1 1 1 1 Short coiled-coil protein Suppressor_APC PF11414.8 EAQ93017.1 - 0.067 13.3 0.3 0.2 11.7 0.4 1.7 2 0 0 2 2 2 0 Adenomatous polyposis coli tumour suppressor protein Rrn6 PF10214.9 EAQ93018.1 - 0.0092 14.5 0.0 0.0092 14.5 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase I-specific transcription-initiation factor MFS_1 PF07690.16 EAQ93019.1 - 1.8e-29 102.8 30.9 2.5e-29 102.3 30.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Trp_oprn_chp PF09534.10 EAQ93019.1 - 0.1 12.4 3.3 0.14 11.9 0.0 2.2 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) zf-RVT PF13966.6 EAQ93022.1 - 0.05 14.3 0.0 0.11 13.2 0.0 1.5 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase Glyco_hydro_2_C PF02836.17 EAQ93023.1 - 7.6e-110 366.8 0.0 9.7e-110 366.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.17 EAQ93023.1 - 2.8e-46 158.1 0.0 1.2e-45 156.0 0.0 2.0 1 1 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.18 EAQ93023.1 - 9.4e-43 146.0 1.2 2.5e-42 144.6 0.6 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.21 EAQ93023.1 - 2e-15 57.4 0.0 3.5e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 DUF4981 PF16353.5 EAQ93023.1 - 1.2e-09 38.5 0.3 4.7e-09 36.6 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function(DUF4981) BetaGal_dom4_5 PF13364.6 EAQ93023.1 - 0.00065 20.3 1.0 0.0024 18.4 0.1 2.2 2 0 0 2 2 2 1 Beta-galactosidase jelly roll domain Glyco_hydro_42 PF02449.15 EAQ93023.1 - 0.062 12.6 0.1 0.12 11.7 0.1 1.3 1 0 0 1 1 1 0 Beta-galactosidase Sugar_tr PF00083.24 EAQ93024.1 - 6.7e-97 325.2 20.3 7.7e-97 325.0 20.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EAQ93024.1 - 8.4e-37 126.9 41.6 2.6e-32 112.1 22.4 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EAQ93025.1 - 9.6e-74 248.9 14.7 1.3e-73 248.5 14.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EAQ93025.1 - 3.3e-23 82.2 21.2 1.3e-19 70.4 13.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EAQ93025.1 - 0.015 13.8 2.1 0.022 13.2 2.1 1.2 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 EAQ93025.1 - 1 7.5 8.9 0.61 8.3 0.9 2.8 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 EAQ93026.1 - 8.9e-47 159.7 30.5 8.9e-47 159.7 30.5 2.3 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EAQ93026.1 - 3.6e-12 45.9 29.8 8.4e-12 44.7 11.6 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.13 EAQ93026.1 - 0.00011 20.7 7.7 0.00018 20.1 7.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 EAQ93026.1 - 0.00084 18.3 0.1 0.00084 18.3 0.1 1.7 2 0 0 2 2 2 1 MFS_1 like family DUF2418 PF10332.9 EAQ93026.1 - 0.1 13.1 1.0 0.34 11.5 1.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2418) OATP PF03137.20 EAQ93026.1 - 0.13 10.5 6.7 0.021 13.1 1.2 2.2 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF4115 PF13464.6 EAQ93028.1 - 0.14 12.4 0.1 2.9 8.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4115) RNase_PH PF01138.21 EAQ93029.1 - 4.5e-38 130.7 0.0 6.6e-38 130.2 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Thioredoxin PF00085.20 EAQ93030.1 - 2.1e-07 30.8 0.1 0.0026 17.7 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_6 PF13848.6 EAQ93030.1 - 0.00076 19.4 0.1 0.012 15.5 0.0 2.6 2 1 0 2 2 2 1 Thioredoxin-like domain ERp29_N PF07912.13 EAQ93030.1 - 0.01 16.0 0.1 0.018 15.2 0.1 1.3 1 0 0 1 1 1 0 ERp29, N-terminal domain Thioredoxin_2 PF13098.6 EAQ93030.1 - 0.082 13.4 0.3 0.66 10.5 0.1 2.3 1 1 1 2 2 2 0 Thioredoxin-like domain ThiJ_like PF17124.5 EAQ93030.1 - 0.12 12.0 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 ThiJ/PfpI family-like Vta1 PF04652.16 EAQ93031.1 - 2e-43 147.8 4.6 2e-43 147.8 4.6 1.4 2 0 0 2 2 2 1 Vta1 like Vta1_C PF18097.1 EAQ93031.1 - 2.4e-16 59.1 0.4 5.1e-16 58.1 0.0 1.7 2 0 0 2 2 2 1 Vta1 C-terminal domain Glyco_hydro_61 PF03443.14 EAQ93032.1 - 0.085 12.8 0.1 0.22 11.5 0.0 1.7 2 0 0 2 2 2 0 Glycosyl hydrolase family 61 Acyl-CoA_dh_1 PF00441.24 EAQ93033.1 - 3.4e-20 72.8 4.0 3.4e-20 72.8 4.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EAQ93033.1 - 8.4e-11 42.5 0.2 5.1e-10 40.0 0.2 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EAQ93033.1 - 2.7e-06 27.5 0.0 8e-06 26.0 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EAQ93033.1 - 0.0035 17.6 4.0 0.0035 17.6 4.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Presenilin PF01080.17 EAQ93034.1 - 5.5 5.6 16.4 7.3 5.2 16.4 1.1 1 0 0 1 1 1 0 Presenilin JAB PF01398.21 EAQ93035.1 - 1.9e-27 95.6 0.0 4e-27 94.5 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 EAQ93035.1 - 1.6e-12 47.8 0.4 2.5e-12 47.2 0.4 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 EAQ93035.1 - 1.3e-06 28.2 0.0 2.5e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain DUF5624 PF18538.1 EAQ93035.1 - 0.068 13.3 0.1 0.13 12.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5624) Hist_deacetyl PF00850.19 EAQ93036.1 - 2.5e-79 267.0 0.1 5.7e-79 265.8 0.0 1.6 2 0 0 2 2 2 1 Histone deacetylase domain Peptidase_A4 PF01828.17 EAQ93037.1 - 3.4e-68 229.2 5.0 4e-68 229.0 5.0 1.0 1 0 0 1 1 1 1 Peptidase A4 family ThrE PF06738.12 EAQ93038.1 - 1.2e-67 227.8 6.1 3.5e-66 223.0 1.7 2.3 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 EAQ93038.1 - 5.8e-05 23.2 24.9 0.00026 21.1 1.0 3.4 3 0 0 3 3 3 3 Threonine/Serine exporter, ThrE Amidoligase_2 PF12224.8 EAQ93039.1 - 3.9e-13 49.6 0.0 6.9e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 Putative amidoligase enzyme THOC2_N PF16134.5 EAQ93040.1 - 0.046 12.4 0.2 0.056 12.1 0.2 1.1 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus NOA36 PF06524.12 EAQ93040.1 - 1.1 8.6 7.3 1.6 8.0 7.3 1.3 1 1 0 1 1 1 0 NOA36 protein AA_permease PF00324.21 EAQ93042.1 - 9.5e-123 410.3 46.8 1.1e-122 410.1 46.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EAQ93042.1 - 4.6e-27 94.9 51.1 6.2e-27 94.5 51.1 1.1 1 0 0 1 1 1 1 Amino acid permease Ribonuc_L-PSP PF01042.21 EAQ93044.1 - 3e-18 66.0 0.0 4.5e-18 65.4 0.0 1.3 1 1 0 1 1 1 1 Endoribonuclease L-PSP Aldedh PF00171.22 EAQ93045.1 - 7e-140 466.6 0.0 8.1e-140 466.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family OmdA PF13376.6 EAQ93045.1 - 0.013 15.5 2.4 0.034 14.1 0.1 2.7 2 1 1 3 3 3 0 Bacteriocin-protection, YdeI or OmpD-Associated Amidohydro_2 PF04909.14 EAQ93046.1 - 6e-49 167.4 0.5 8.6e-49 166.9 0.5 1.2 1 0 0 1 1 1 1 Amidohydrolase Ank_2 PF12796.7 EAQ93047.1 - 1.3e-27 96.2 0.0 1.2e-15 57.8 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAQ93047.1 - 8.2e-22 77.0 0.0 3.3e-09 36.8 0.0 4.0 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 EAQ93047.1 - 8.9e-20 70.2 0.0 3e-05 24.2 0.0 4.6 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 EAQ93047.1 - 2.3e-19 69.5 0.0 1.2e-08 35.3 0.0 3.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAQ93047.1 - 3e-14 51.7 0.0 0.026 15.1 0.0 4.6 4 0 0 4 4 4 3 Ankyrin repeat RNF220 PF15926.5 EAQ93047.1 - 0.049 13.3 0.1 0.13 11.9 0.1 1.7 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase RNF220 DUF2946 PF11162.8 EAQ93047.1 - 1.6 9.4 5.5 4.9 7.9 1.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2946) MITF_TFEB_C_3_N PF15951.5 EAQ93048.1 - 0.17 12.5 0.1 6 7.5 0.2 2.3 2 0 0 2 2 2 0 MITF/TFEB/TFEC/TFE3 N-terminus Amidohydro_3 PF07969.11 EAQ93049.1 - 2.7e-39 135.9 7.8 3.4e-39 135.6 7.8 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 EAQ93049.1 - 0.00011 21.7 0.3 0.12 11.7 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family AP_endonuc_2 PF01261.24 EAQ93049.1 - 0.02 14.3 0.2 0.034 13.6 0.2 1.4 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel 2OG-FeII_Oxy_3 PF13640.6 EAQ93050.1 - 1.1e-10 42.2 0.3 5.6e-10 40.0 0.3 1.9 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily GBV-C_env PF12786.7 EAQ93050.1 - 0.069 11.8 0.0 0.11 11.1 0.0 1.3 1 0 0 1 1 1 0 GB virus C genotype envelope adh_short_C2 PF13561.6 EAQ93051.1 - 5e-33 114.6 0.1 3.8e-22 79.0 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EAQ93051.1 - 9.9e-15 54.5 0.1 1.9e-09 37.2 0.1 2.2 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 EAQ93051.1 - 4.4e-06 26.7 0.4 8.3e-06 25.8 0.4 1.4 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 EAQ93051.1 - 0.0019 17.3 0.0 0.0028 16.7 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EAQ93051.1 - 0.0042 16.6 0.0 0.0068 15.9 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Methyltransf_25 PF13649.6 EAQ93051.1 - 0.041 14.6 0.0 0.09 13.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Sacchrp_dh_NADP PF03435.18 EAQ93051.1 - 0.059 13.6 0.2 0.11 12.8 0.2 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Pkinase PF00069.25 EAQ93052.1 - 9.8e-74 248.0 0.0 1.4e-73 247.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ93052.1 - 3.3e-36 124.9 0.0 6.1e-36 124.0 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAQ93052.1 - 0.0011 18.4 0.4 0.5 9.6 0.0 2.7 3 0 0 3 3 3 2 Kinase-like Pkinase_fungal PF17667.1 EAQ93052.1 - 0.018 13.9 0.0 0.018 13.9 0.0 2.0 3 1 0 4 4 4 0 Fungal protein kinase APH PF01636.23 EAQ93052.1 - 0.025 14.5 0.0 0.064 13.2 0.0 1.8 1 0 0 1 1 1 0 Phosphotransferase enzyme family Peptidase_S28 PF05577.12 EAQ93053.1 - 8.5e-41 140.1 0.9 2.2e-33 115.7 0.3 2.1 1 1 0 2 2 2 2 Serine carboxypeptidase S28 PAP2 PF01569.21 EAQ93054.1 - 4.7e-14 52.3 0.2 8.8e-14 51.4 0.2 1.4 1 0 0 1 1 1 1 PAP2 superfamily AMP-binding PF00501.28 EAQ93055.1 - 4.3e-73 246.3 0.0 1.1e-72 245.0 0.0 1.7 2 0 0 2 2 2 1 AMP-binding enzyme NAD_binding_4 PF07993.12 EAQ93055.1 - 1.2e-69 234.3 0.0 1.7e-69 233.8 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 EAQ93055.1 - 1.8e-10 40.7 0.0 3.4e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 EAQ93055.1 - 1.7e-09 37.9 0.0 3.8e-09 36.8 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.19 EAQ93055.1 - 2.1e-07 30.3 0.0 6e-07 28.7 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family AMP-binding_C PF13193.6 EAQ93055.1 - 4.1e-05 24.5 0.0 0.00031 21.7 0.0 2.6 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain NAD_binding_10 PF13460.6 EAQ93055.1 - 0.0022 17.9 3.3 0.33 10.8 1.6 3.8 2 1 1 3 3 3 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 EAQ93055.1 - 0.03 13.5 0.0 0.062 12.4 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 EAQ93055.1 - 0.032 13.4 0.0 0.11 11.5 0.0 1.9 1 1 0 1 1 1 0 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 EAQ93055.1 - 0.083 12.3 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase AAR2 PF05282.11 EAQ93055.1 - 0.097 12.1 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 AAR2 protein SUR7 PF06687.12 EAQ93057.1 - 1.4e-13 51.0 0.1 2e-13 50.5 0.1 1.2 1 0 0 1 1 1 1 SUR7/PalI family LYRIC PF15686.5 EAQ93057.1 - 0.0021 17.7 0.6 0.0021 17.7 0.6 1.6 1 1 1 2 2 2 1 Lysine-rich CEACAM1 co-isolated protein family Cytochrom_B558a PF05038.13 EAQ93057.1 - 0.44 10.1 2.9 2.9 7.4 1.2 2.7 2 1 1 3 3 3 0 Cytochrome Cytochrome b558 alpha-subunit Fig1 PF12351.8 EAQ93057.1 - 3 7.7 6.3 5.8 6.8 6.3 1.5 1 0 0 1 1 1 0 Ca2+ regulator and membrane fusion protein Fig1 SET PF00856.28 EAQ93058.1 - 1.9e-13 51.1 0.0 7.3e-13 49.3 0.0 1.9 1 1 0 1 1 1 1 SET domain SAF PF08666.12 EAQ93058.1 - 0.07 13.8 0.1 15 6.3 0.0 2.4 2 0 0 2 2 2 0 SAF domain Amidoligase_2 PF12224.8 EAQ93060.1 - 4.9e-12 46.0 0.7 1.7e-11 44.3 0.2 2.1 2 1 0 2 2 2 1 Putative amidoligase enzyme SET PF00856.28 EAQ93061.1 - 2.6e-13 50.7 0.0 2.3e-12 47.6 0.0 2.2 1 1 0 1 1 1 1 SET domain TPR_2 PF07719.17 EAQ93061.1 - 1.9e-08 33.8 1.4 8.9e-05 22.3 0.2 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 EAQ93061.1 - 0.00019 21.1 1.3 0.02 14.7 0.1 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 EAQ93061.1 - 0.0066 16.6 0.5 1.4 9.4 0.1 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 EAQ93061.1 - 0.0075 16.9 0.7 0.06 14.0 0.9 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 EAQ93061.1 - 0.0079 16.5 0.9 0.2 12.0 0.1 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF4678 PF15727.5 EAQ93061.1 - 0.21 10.8 0.3 0.44 9.8 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4678) NACHT PF05729.12 EAQ93062.1 - 8.4e-07 29.0 0.0 2.3e-06 27.7 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 EAQ93062.1 - 1.4e-05 25.4 0.0 5.2e-05 23.5 0.0 2.0 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 EAQ93062.1 - 2.3e-05 24.4 0.0 7.8e-05 22.7 0.0 1.8 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Acetyltransf_1 PF00583.25 EAQ93062.1 - 0.00017 21.8 0.0 0.00046 20.4 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family AAA_33 PF13671.6 EAQ93062.1 - 0.0021 18.2 0.0 0.0076 16.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain Acetyltransf_7 PF13508.7 EAQ93062.1 - 0.0029 18.0 0.0 0.0083 16.5 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EAQ93062.1 - 0.018 15.0 0.0 0.076 13.0 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Mitovir_RNA_pol PF05919.11 EAQ93062.1 - 0.032 13.4 0.0 0.064 12.4 0.0 1.4 2 0 0 2 2 2 0 Mitovirus RNA-dependent RNA polymerase Helo_like_N PF17111.5 EAQ93062.1 - 0.045 13.1 0.1 0.15 11.4 0.1 1.8 1 1 0 1 1 1 0 Fungal N-terminal domain of STAND proteins AAA_16 PF13191.6 EAQ93062.1 - 0.046 14.1 0.0 0.15 12.4 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain DUF2075 PF09848.9 EAQ93062.1 - 0.12 11.6 0.0 0.42 9.8 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.22 EAQ93062.1 - 0.17 12.3 0.0 0.43 11.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA PF00004.29 EAQ93062.1 - 0.19 12.1 0.0 0.53 10.7 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Hemerythrin PF01814.23 EAQ93063.1 - 2.3e-07 31.5 0.2 3.1e-07 31.1 0.2 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Fungal_trans_2 PF11951.8 EAQ93064.1 - 7.4e-55 186.3 1.1 1.1e-54 185.7 1.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EAQ93064.1 - 5e-08 32.9 5.3 1.1e-07 31.8 5.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MARVEL PF01284.23 EAQ93065.1 - 0.0047 17.0 14.2 0.0074 16.3 14.2 1.2 1 0 0 1 1 1 1 Membrane-associating domain ENTH PF01417.20 EAQ93066.1 - 6.1e-47 158.8 0.1 9.3e-47 158.2 0.1 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 EAQ93066.1 - 0.00018 20.6 0.1 0.00024 20.2 0.1 1.1 1 0 0 1 1 1 1 ANTH domain Pro_isomerase PF00160.21 EAQ93067.1 - 3.3e-15 56.7 0.1 3.9e-15 56.5 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RNA_pol_Rpc34 PF05158.12 EAQ93068.1 - 1.7e-137 458.3 0.0 2.1e-137 458.0 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit RPA_C PF08784.11 EAQ93068.1 - 0.00048 20.7 2.7 0.012 16.3 0.0 3.1 3 1 0 3 3 3 1 Replication protein A C terminal HTH_34 PF13601.6 EAQ93068.1 - 0.022 14.9 0.0 0.055 13.6 0.0 1.6 1 0 0 1 1 1 0 Winged helix DNA-binding domain B-block_TFIIIC PF04182.12 EAQ93068.1 - 0.052 13.7 0.1 5.3 7.3 0.0 3.1 3 0 0 3 3 3 0 B-block binding subunit of TFIIIC Rrf2 PF02082.20 EAQ93068.1 - 0.065 13.6 0.0 13 6.3 0.0 2.3 2 0 0 2 2 2 0 Transcriptional regulator MarR PF01047.22 EAQ93068.1 - 0.12 12.4 0.0 0.44 10.5 0.0 1.9 3 0 0 3 3 3 0 MarR family MFS_1 PF07690.16 EAQ93069.1 - 5.1e-31 107.9 28.1 1.1e-30 106.7 18.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily GPI-anchored PF10342.9 EAQ93070.1 - 1.2e-16 61.3 1.3 1.2e-16 61.3 1.3 1.9 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family p450 PF00067.22 EAQ93071.1 - 2.2e-46 158.6 0.0 7.4e-39 133.8 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 TPR_1 PF00515.28 EAQ93074.1 - 2.8e-38 128.2 28.4 1.9e-06 27.4 0.1 9.9 10 0 0 10 10 10 7 Tetratricopeptide repeat STI1 PF17830.1 EAQ93074.1 - 5.8e-38 128.6 16.0 9.6e-21 73.5 3.5 3.1 4 0 0 4 4 3 2 STI1 domain TPR_2 PF07719.17 EAQ93074.1 - 2.3e-30 102.2 33.3 0.00022 21.1 0.0 10.2 11 0 0 11 11 10 8 Tetratricopeptide repeat TPR_11 PF13414.6 EAQ93074.1 - 3e-16 58.8 22.3 0.002 17.8 0.5 8.0 8 0 0 8 8 8 4 TPR repeat TPR_12 PF13424.6 EAQ93074.1 - 2.9e-14 53.1 16.4 5.7e-10 39.4 0.8 6.1 4 2 2 6 6 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 EAQ93074.1 - 4e-14 53.0 13.8 0.0016 19.1 0.3 6.2 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 EAQ93074.1 - 4.3e-14 51.5 25.4 0.00021 21.3 0.3 7.8 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_14 PF13428.6 EAQ93074.1 - 1.4e-12 47.3 5.3 0.11 13.3 0.0 7.8 5 2 2 7 7 7 1 Tetratricopeptide repeat TPR_7 PF13176.6 EAQ93074.1 - 1.6e-12 46.5 9.5 0.0015 18.4 0.0 7.1 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 EAQ93074.1 - 1.9e-11 44.3 13.8 0.04 14.4 0.1 6.8 5 2 2 7 7 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 EAQ93074.1 - 1.9e-09 37.3 9.1 5.6 7.6 0.0 8.0 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_9 PF13371.6 EAQ93074.1 - 9.8e-09 35.2 2.1 0.0046 17.1 0.0 4.4 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_10 PF13374.6 EAQ93074.1 - 3.5e-05 23.5 12.8 0.97 9.4 0.1 6.5 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_MalT PF17874.1 EAQ93074.1 - 0.00074 19.0 0.5 0.017 14.5 0.0 2.6 3 0 0 3 3 3 1 MalT-like TPR region TPR_6 PF13174.6 EAQ93074.1 - 0.016 15.8 16.6 0.084 13.5 0.1 7.3 7 0 0 7 7 7 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EAQ93074.1 - 0.06 13.6 8.0 2.4 8.4 2.6 3.8 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF5486 PF17588.2 EAQ93074.1 - 0.24 11.3 5.9 1.1 9.2 1.8 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5486) Fis1_TPR_C PF14853.6 EAQ93074.1 - 0.28 11.3 6.9 4.4 7.5 0.1 4.6 6 0 0 6 6 5 0 Fis1 C-terminal tetratricopeptide repeat XPC-binding PF09280.11 EAQ93074.1 - 0.5 10.1 8.7 4.6 7.1 1.0 3.2 3 0 0 3 3 3 0 XPC-binding domain DUF5113 PF17140.4 EAQ93074.1 - 1.5 8.6 6.9 6.4 6.6 0.2 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF5113) HMG-CoA_red PF00368.18 EAQ93075.1 - 9.9e-107 357.1 4.2 1.1e-106 357.0 4.2 1.0 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase MFS_1 PF07690.16 EAQ93076.1 - 3.6e-40 138.0 60.1 3.6e-40 138.0 60.1 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EAQ93076.1 - 9.4e-15 54.4 11.3 9.4e-15 54.4 11.3 2.7 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 EAQ93076.1 - 9e-14 50.8 25.8 1.2e-13 50.4 25.8 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) HD_4 PF13328.6 EAQ93076.1 - 0.061 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 HD domain Esterase_phd PF10503.9 EAQ93077.1 - 5.8e-26 91.4 0.7 8.3e-26 90.8 0.7 1.1 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 EAQ93077.1 - 7.4e-13 48.5 1.1 1.3e-12 47.7 1.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family CBM_1 PF00734.18 EAQ93077.1 - 9.7e-12 44.6 12.5 4.4e-11 42.5 12.5 2.3 1 0 0 1 1 1 1 Fungal cellulose binding domain Esterase PF00756.20 EAQ93077.1 - 0.00038 20.2 0.3 0.0006 19.5 0.3 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_3 PF07859.13 EAQ93077.1 - 0.0013 18.7 0.1 0.002 18.1 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 EAQ93077.1 - 0.02 13.8 0.2 0.033 13.1 0.0 1.5 2 0 0 2 2 2 0 Carboxylesterase family Abhydrolase_2 PF02230.16 EAQ93077.1 - 0.083 12.7 0.1 0.19 11.5 0.1 1.5 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Toxin_7 PF05980.12 EAQ93077.1 - 0.1 12.9 4.7 0.25 11.6 4.7 1.7 1 0 0 1 1 1 0 Toxin 7 BAAT_C PF08840.11 EAQ93077.1 - 0.16 11.9 0.1 0.36 10.7 0.1 1.5 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Glyco_hydro_3 PF00933.21 EAQ93078.1 - 4.9e-29 101.7 0.0 8.2e-29 101.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 EAQ93078.1 - 3.3e-16 59.9 0.0 7e-16 58.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain RRM_1 PF00076.22 EAQ93079.1 - 1.3e-20 73.0 0.0 3e-11 43.0 0.0 2.6 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SPOR PF05036.13 EAQ93079.1 - 0.0034 17.7 0.1 4 7.9 0.0 2.5 2 0 0 2 2 2 2 Sporulation related domain RRM_5 PF13893.6 EAQ93079.1 - 0.029 14.0 0.0 1.5 8.4 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 EAQ93079.1 - 0.041 13.9 0.0 2.1 8.5 0.0 2.3 2 0 0 2 2 2 0 Limkain b1 RRM_occluded PF16842.5 EAQ93079.1 - 0.073 12.9 0.0 3.9 7.4 0.0 2.3 2 0 0 2 2 2 0 Occluded RNA-recognition motif Nup35_RRM PF05172.13 EAQ93079.1 - 0.12 12.4 0.0 0.36 10.8 0.0 1.7 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif bZIP_1 PF00170.21 EAQ93080.1 - 0.0081 16.2 8.6 0.012 15.7 8.6 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EAQ93080.1 - 0.75 9.9 12.4 1.6 8.9 12.4 1.5 1 0 0 1 1 1 0 Basic region leucine zipper GFO_IDH_MocA PF01408.22 EAQ93081.1 - 7.1e-06 26.9 0.0 1.6e-05 25.7 0.0 1.5 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold WSC PF01822.19 EAQ93082.1 - 2.1e-16 59.9 12.2 3.1e-11 43.3 3.4 3.4 3 0 0 3 3 3 2 WSC domain LysM PF01476.20 EAQ93082.1 - 0.0083 16.2 0.0 0.082 13.0 0.0 2.6 3 0 0 3 3 3 1 LysM domain Bowman-Birk_leg PF00228.20 EAQ93082.1 - 0.19 12.2 2.4 0.46 10.9 0.2 3.0 2 0 0 2 2 2 0 Bowman-Birk serine protease inhibitor family Chitin_bind_1 PF00187.19 EAQ93083.1 - 1.9e-10 41.1 28.3 5.3e-06 26.8 3.6 2.4 2 0 0 2 2 2 2 Chitin recognition protein zf-RVT PF13966.6 EAQ93083.1 - 0.093 13.5 0.0 0.32 11.7 0.0 1.9 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase F-box-like PF12937.7 EAQ93084.1 - 0.00047 20.0 0.1 0.0018 18.1 0.1 2.0 1 0 0 1 1 1 1 F-box-like HTH_51 PF18558.1 EAQ93084.1 - 0.075 12.9 0.0 0.34 10.8 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain LRR_6 PF13516.6 EAQ93084.1 - 0.085 13.0 0.2 13 6.1 0.0 3.7 3 0 0 3 3 3 0 Leucine Rich repeat F-box_4 PF15966.5 EAQ93084.1 - 0.11 12.3 0.2 0.23 11.3 0.2 1.5 1 0 0 1 1 1 0 F-box RVT_1 PF00078.27 EAQ93086.1 - 1.1e-37 129.7 0.0 5.8e-37 127.3 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 EAQ93086.1 - 1.1e-24 86.5 0.0 4.6e-24 84.6 0.0 2.2 2 0 0 2 2 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 EAQ93086.1 - 0.00015 21.3 0.3 0.0003 20.4 0.3 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SlyX PF04102.12 EAQ93086.1 - 0.0083 16.7 5.5 0.065 13.9 5.5 2.6 1 1 0 1 1 1 1 SlyX zf-CCHC PF00098.23 EAQ93086.1 - 0.0092 16.0 2.5 0.0092 16.0 2.5 2.5 2 0 0 2 2 1 1 Zinc knuckle USP8_interact PF08941.10 EAQ93086.1 - 0.075 12.8 0.1 0.19 11.5 0.1 1.7 1 0 0 1 1 1 0 USP8 interacting HMMR_N PF15905.5 EAQ93086.1 - 0.077 12.5 0.5 0.14 11.6 0.5 1.3 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal CENP-F_leu_zip PF10473.9 EAQ93086.1 - 0.092 12.8 0.8 0.24 11.4 0.8 1.7 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PKcGMP_CC PF16808.5 EAQ93086.1 - 0.12 12.3 0.5 0.38 10.6 0.5 1.9 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase CorA PF01544.18 EAQ93086.1 - 0.14 11.5 1.7 0.25 10.6 1.7 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein UPF0242 PF06785.11 EAQ93086.1 - 0.33 11.0 1.3 0.66 10.0 1.3 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF3584 PF12128.8 EAQ93086.1 - 0.69 7.4 5.7 1 6.8 5.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) YlqD PF11068.8 EAQ93086.1 - 1 9.7 3.9 3.4 8.0 3.9 1.8 1 0 0 1 1 1 0 YlqD protein DUF2968 PF11180.8 EAQ93086.1 - 1.1 8.9 5.4 2.6 7.7 5.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) Herpes_pp85 PF04637.12 EAQ93086.1 - 3.7 5.9 5.7 1.9 6.8 3.1 1.7 2 0 0 2 2 2 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Pkinase PF00069.25 EAQ93087.1 - 2.6e-27 95.9 0.0 8.8e-27 94.1 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ93087.1 - 4.4e-09 36.0 0.4 1.4e-07 31.1 0.2 2.7 2 1 0 2 2 2 1 Protein tyrosine kinase Glyco_hydro_26 PF02156.15 EAQ93088.1 - 1.4e-83 281.0 3.5 1.9e-83 280.5 3.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 26 CBM_35 PF16990.5 EAQ93088.1 - 3.2e-30 104.9 0.6 5.6e-30 104.1 0.6 1.4 1 0 0 1 1 1 1 Carbohydrate binding module (family 35) DUF2436 PF10365.9 EAQ93088.1 - 0.049 13.4 0.0 0.14 11.9 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF2436) Sod_Cu PF00080.20 EAQ93089.1 - 1.4e-06 28.5 1.5 4.1e-05 23.8 0.2 2.1 1 1 1 2 2 2 2 Copper/zinc superoxide dismutase (SODC) p450 PF00067.22 EAQ93090.1 - 4.8e-26 91.5 0.0 6.9e-25 87.7 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 DUF166 PF02593.14 EAQ93092.1 - 0.037 13.6 0.0 0.059 12.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function Ribosomal_L44 PF00935.19 EAQ93093.1 - 1.9e-36 124.4 11.9 2.8e-36 123.8 11.9 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 DUF3433 PF11915.8 EAQ93095.1 - 5.7e-21 74.8 5.5 5.7e-21 74.8 5.5 1.9 3 0 0 3 3 3 1 Protein of unknown function (DUF3433) DUF4834 PF16118.5 EAQ93096.1 - 0.014 16.3 0.1 0.02 15.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Mito_fiss_reg PF05308.11 EAQ93096.1 - 0.025 14.7 0.2 0.032 14.3 0.2 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator DUF2448 PF10476.9 EAQ93096.1 - 0.03 14.2 0.4 0.04 13.8 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2448) DUF3328 PF11807.8 EAQ93096.1 - 0.29 10.9 0.5 0.36 10.6 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) Menin PF05053.13 EAQ93096.1 - 0.35 9.2 1.1 0.39 9.0 1.1 1.1 1 0 0 1 1 1 0 Menin Shisa PF13908.6 EAQ93096.1 - 0.47 10.7 2.3 0.59 10.3 2.3 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator NUDE_C PF04880.13 EAQ93096.1 - 2.3 8.7 6.3 3.2 8.2 6.3 1.3 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region LPMO_10 PF03067.15 EAQ93097.1 - 3.9e-07 30.9 4.0 9.2e-07 29.7 0.1 2.2 2 0 0 2 2 2 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading TFIIF_alpha PF05793.12 EAQ93097.1 - 2.6 6.6 7.2 3.7 6.0 7.2 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SDA1 PF05285.12 EAQ93097.1 - 3.3 7.0 7.1 4.5 6.6 7.1 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 EAQ93097.1 - 3.4 5.8 6.5 4.2 5.5 6.5 1.0 1 0 0 1 1 1 0 Nop14-like family Herpes_Helicase PF02689.14 EAQ93098.1 - 0.00019 19.5 0.0 0.00026 19.1 0.0 1.1 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.6 EAQ93098.1 - 0.00036 20.3 0.0 0.00082 19.2 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain RVT_1 PF00078.27 EAQ93099.1 - 0.00075 19.1 0.0 0.014 14.9 0.0 2.1 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) PIF1 PF05970.14 EAQ93101.1 - 1e-18 67.7 0.0 1.7e-18 66.9 0.0 1.3 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 EAQ93101.1 - 2e-07 31.0 0.1 6.3e-07 29.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EAQ93101.1 - 0.00099 19.5 0.0 0.0025 18.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 EAQ93101.1 - 0.01 15.7 0.0 0.029 14.2 0.0 1.9 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain MFS_1 PF07690.16 EAQ93102.1 - 5.3e-06 25.6 29.9 1.7e-05 23.9 26.3 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 EAQ93102.1 - 0.0019 17.1 0.0 0.0034 16.3 0.0 1.4 1 1 0 1 1 1 1 MFS_1 like family Zn_clus PF00172.18 EAQ93103.1 - 5.8e-10 39.1 10.8 1.4e-09 37.9 10.8 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EAQ93103.1 - 0.0012 18.0 0.0 0.0018 17.4 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain p450 PF00067.22 EAQ93104.1 - 1.6e-08 33.7 0.1 4.6e-06 25.6 0.1 2.1 1 1 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 EAQ93106.1 - 7.1e-24 84.4 50.7 7.9e-19 67.8 36.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4731 PF15875.5 EAQ93106.1 - 8.6 6.6 5.9 16 5.8 0.1 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4731) Ferric_reduct PF01794.19 EAQ93107.1 - 5.3e-24 84.7 12.6 5.3e-24 84.7 12.6 2.8 3 1 1 4 4 4 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 EAQ93107.1 - 6.4e-06 26.2 0.0 1.4e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain Peptidase_U4 PF03419.13 EAQ93107.1 - 0.1 11.9 4.5 0.2 10.9 4.5 1.5 1 0 0 1 1 1 0 Sporulation factor SpoIIGA Methyltransf_25 PF13649.6 EAQ93108.1 - 1.3e-11 45.1 0.0 2e-11 44.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAQ93108.1 - 5.9e-10 39.1 0.0 7.2e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EAQ93108.1 - 2.8e-09 37.5 0.0 4.4e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EAQ93108.1 - 3.1e-08 33.2 0.0 4.2e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 EAQ93108.1 - 3.3e-07 31.0 0.0 4.9e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EAQ93108.1 - 7.4e-06 25.6 0.0 1e-05 25.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 EAQ93108.1 - 0.00023 20.8 0.0 0.00033 20.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 EAQ93108.1 - 0.0011 18.8 0.0 0.0015 18.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 EAQ93108.1 - 0.0012 18.5 0.0 0.0018 17.9 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_2 PF00891.18 EAQ93108.1 - 0.014 14.7 0.0 0.018 14.4 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_9 PF08003.11 EAQ93108.1 - 0.083 11.8 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) RraA-like PF03737.15 EAQ93109.1 - 5.6e-23 81.8 0.0 6.7e-23 81.5 0.0 1.0 1 0 0 1 1 1 1 Aldolase/RraA YqfQ PF14181.6 EAQ93109.1 - 0.35 11.1 1.1 0.64 10.2 0.9 1.4 1 1 1 2 2 2 0 YqfQ-like protein MMM1 PF10296.9 EAQ93110.1 - 0.024 13.7 0.7 0.032 13.3 0.0 1.5 2 0 0 2 2 2 0 Maintenance of mitochondrial morphology protein 1 Phage_holin_2_4 PF16082.5 EAQ93110.1 - 8.6 6.2 8.2 33 4.3 0.0 2.7 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like MFS_1 PF07690.16 EAQ93111.1 - 2.6e-22 79.2 59.8 5.6e-15 55.1 32.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily YrhC PF14143.6 EAQ93111.1 - 3.8 7.7 0.0 3.8 7.7 0.0 3.6 5 0 0 5 5 5 0 YrhC-like protein FMN_red PF03358.15 EAQ93112.1 - 3.3e-08 33.4 0.0 4.8e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 EAQ93112.1 - 8.4e-07 28.9 0.0 1.2e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.25 EAQ93112.1 - 0.00041 20.6 0.4 0.0031 17.7 0.4 2.3 1 1 0 1 1 1 1 Flavodoxin Yae1_N PF09811.9 EAQ93113.1 - 3.1e-11 42.8 3.3 6.9e-11 41.7 3.3 1.6 1 0 0 1 1 1 1 Essential protein Yae1, N terminal Ribosomal_S8 PF00410.19 EAQ93115.1 - 4e-10 39.7 0.0 1.5e-09 37.9 0.0 1.8 1 1 0 1 1 1 1 Ribosomal protein S8 SPO11_like PF03533.14 EAQ93115.1 - 0.028 14.5 0.3 0.068 13.3 0.3 1.7 1 0 0 1 1 1 0 SPO11 homologue Iso_dh PF00180.20 EAQ93118.1 - 2.5e-96 322.9 0.0 3.5e-96 322.4 0.0 1.2 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF1447 PF07288.11 EAQ93118.1 - 0.2 11.7 0.2 0.52 10.4 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1447) GTP_EFTU PF00009.27 EAQ93119.1 - 2.6e-58 196.8 0.2 5e-58 195.8 0.2 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 EAQ93119.1 - 4.5e-33 113.2 0.0 8.7e-33 112.3 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.18 EAQ93119.1 - 5.6e-33 113.3 0.0 1.2e-32 112.3 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 EAQ93119.1 - 8.5e-22 77.0 0.0 1.8e-21 75.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EAQ93119.1 - 2.8e-14 53.3 0.0 6.7e-14 52.0 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 EAQ93119.1 - 4.6e-07 29.7 0.0 1.1e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 EAQ93119.1 - 0.034 14.2 0.0 0.074 13.1 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase Asp PF00026.23 EAQ93120.1 - 2.4e-64 217.8 0.3 3.4e-64 217.2 0.3 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EAQ93120.1 - 4.1e-11 43.4 0.3 1.2e-06 28.9 0.0 2.7 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EAQ93120.1 - 0.00095 19.8 0.1 0.18 12.5 0.1 2.7 2 1 0 2 2 2 1 Aspartyl protease TAXi_C PF14541.6 EAQ93120.1 - 0.045 13.5 0.0 0.11 12.3 0.0 1.7 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 EAQ93120.1 - 0.063 13.8 0.0 15 6.2 0.0 3.0 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease PDZ_1 PF12812.7 EAQ93120.1 - 0.12 12.4 0.0 1.1 9.4 0.0 2.3 2 0 0 2 2 2 0 PDZ-like domain Aminotran_1_2 PF00155.21 EAQ93122.1 - 2e-36 126.0 0.0 2.5e-36 125.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EAQ93122.1 - 8.1e-06 24.6 0.0 1.2e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 EAQ93122.1 - 1.2e-05 24.5 0.0 2.3e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_MocR PF12897.7 EAQ93122.1 - 0.01 14.7 0.0 0.013 14.3 0.0 1.3 1 1 0 1 1 1 0 Alanine-glyoxylate amino-transferase DegT_DnrJ_EryC1 PF01041.17 EAQ93122.1 - 0.043 13.1 0.0 0.075 12.3 0.0 1.4 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Alliinase_C PF04864.13 EAQ93122.1 - 0.22 10.3 0.0 0.35 9.7 0.0 1.2 1 0 0 1 1 1 0 Allinase ABC2_membrane PF01061.24 EAQ93123.1 - 4.8e-39 134.0 22.4 9.3e-39 133.0 22.4 1.5 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 EAQ93123.1 - 2.1e-24 86.6 0.0 3.8e-24 85.7 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 EAQ93123.1 - 4.7e-07 29.2 28.9 2.2e-06 27.0 28.9 2.0 1 1 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 EAQ93123.1 - 2.2e-05 24.5 0.0 0.25 11.1 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EAQ93123.1 - 0.008 15.9 0.1 0.018 14.8 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_18 PF13238.6 EAQ93123.1 - 0.018 15.6 0.0 0.044 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAQ93123.1 - 0.018 14.6 0.1 0.043 13.4 0.1 1.6 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 EAQ93123.1 - 0.021 14.3 0.0 0.38 10.2 0.0 2.2 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EAQ93123.1 - 0.025 14.5 0.0 0.065 13.1 0.0 1.6 2 0 0 2 2 2 0 RsgA GTPase NADH-G_4Fe-4S_3 PF10588.9 EAQ93123.1 - 0.036 13.6 0.6 5.3 6.7 0.0 2.8 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region AAA_23 PF13476.6 EAQ93123.1 - 0.056 13.9 0.1 0.1 13.1 0.1 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EAQ93123.1 - 0.074 13.0 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_33 PF13671.6 EAQ93123.1 - 0.12 12.6 0.0 0.52 10.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EAQ93123.1 - 0.12 12.7 0.0 0.26 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EAQ93123.1 - 0.16 12.3 0.0 0.32 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.6 EAQ93123.1 - 0.18 12.0 0.0 0.34 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC2_membrane_2 PF12679.7 EAQ93123.1 - 4 6.6 21.5 5.1e+02 -0.3 21.5 2.2 1 1 0 1 1 1 0 ABC-2 family transporter protein SPT16 PF08644.11 EAQ93124.1 - 0.24 11.6 2.0 1 9.6 0.2 2.2 1 1 1 2 2 2 0 FACT complex subunit (SPT16/CDC68) NGP1NT PF08153.12 EAQ93125.1 - 1.6e-49 167.4 0.6 2.4e-49 166.8 0.6 1.3 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 EAQ93125.1 - 1.4e-15 57.3 0.0 2.8e-15 56.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EAQ93125.1 - 7e-06 25.7 0.0 1.2e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EAQ93125.1 - 0.0011 19.0 0.1 0.15 12.1 0.1 2.7 1 1 1 2 2 2 1 Dynamin family RsgA_GTPase PF03193.16 EAQ93125.1 - 0.0034 17.3 0.0 0.0063 16.4 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase APT PF03440.14 EAQ93126.1 - 0.089 12.8 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Aerolysin/Pertussis toxin (APT) domain Thioredoxin_4 PF13462.6 EAQ93128.1 - 2.8e-05 24.4 0.0 0.00027 21.1 0.0 2.0 1 1 0 2 2 2 1 Thioredoxin Thioredoxin_3 PF13192.6 EAQ93128.1 - 0.037 14.1 0.1 0.053 13.6 0.1 1.4 1 0 0 1 1 1 0 Thioredoxin domain DSBA PF01323.20 EAQ93128.1 - 0.068 12.9 2.4 3.7 7.3 0.3 2.2 2 0 0 2 2 2 0 DSBA-like thioredoxin domain DUF1713 PF08213.11 EAQ93129.1 - 5.3e-09 35.9 21.7 1e-08 34.9 21.7 1.5 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) ER-remodelling PF14755.6 EAQ93129.1 - 1.9 8.8 11.1 1.1 9.5 5.6 2.6 2 1 0 2 2 2 0 Intracellular membrane remodeller Raffinose_syn PF05691.12 EAQ93130.1 - 9.7e-49 165.8 0.6 4.1e-40 137.3 0.0 3.1 2 1 1 3 3 3 3 Raffinose synthase or seed imbibition protein Sip1 Melibiase PF02065.18 EAQ93130.1 - 0.019 13.9 0.0 0.029 13.3 0.0 1.2 1 0 0 1 1 1 0 Melibiase DUF5037 PF16440.5 EAQ93130.1 - 0.044 13.3 0.0 0.073 12.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5037) AIRC PF00731.20 EAQ93131.1 - 5.5e-59 198.0 1.6 1.3e-58 196.8 1.6 1.7 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.22 EAQ93131.1 - 1.3e-34 119.2 0.0 1.3e-33 116.0 0.0 2.3 1 1 0 1 1 1 1 ATP-grasp domain PurK_C PF17769.1 EAQ93131.1 - 7.7e-14 51.1 0.0 1.9e-13 49.9 0.0 1.7 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain XdhC_C PF13478.6 EAQ93131.1 - 0.0031 18.0 0.0 2.1 8.9 0.0 2.7 2 0 0 2 2 2 2 XdhC Rossmann domain 2-Hacid_dh_C PF02826.19 EAQ93131.1 - 0.0047 16.3 0.0 0.0091 15.4 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CPSase_L_D2 PF02786.17 EAQ93131.1 - 0.021 14.3 1.0 1.5 8.3 0.0 2.6 3 0 0 3 3 3 0 Carbamoyl-phosphate synthase L chain, ATP binding domain PrpR_N PF06506.11 EAQ93131.1 - 0.038 13.6 0.2 0.6 9.7 0.0 2.7 3 0 0 3 3 3 0 Propionate catabolism activator ATPgrasp_N PF18130.1 EAQ93131.1 - 0.04 14.5 0.2 1.1 9.8 0.0 2.9 2 0 0 2 2 2 0 ATP-grasp N-terminal domain 3HCDH_N PF02737.18 EAQ93131.1 - 0.092 12.6 0.0 1.2 9.0 0.0 2.7 2 1 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Strep_SA_rep PF06696.11 EAQ93131.1 - 3.5 7.7 6.2 1.8 8.6 3.5 2.0 2 0 0 2 2 2 0 Streptococcal surface antigen repeat Peptidase_M16 PF00675.20 EAQ93132.1 - 7.1e-57 191.6 0.4 2.2e-56 190.0 0.5 1.8 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EAQ93132.1 - 3.3e-36 125.0 0.0 2e-35 122.5 0.0 2.1 2 0 0 2 2 2 1 Peptidase M16 inactive domain M16C_assoc PF08367.11 EAQ93132.1 - 0.015 14.4 0.1 0.03 13.4 0.1 1.5 1 0 0 1 1 1 0 Peptidase M16C associated RbsD_FucU PF05025.13 EAQ93132.1 - 0.032 14.6 0.2 0.15 12.4 0.1 2.2 2 0 0 2 2 2 0 RbsD / FucU transport protein family Esterase PF00756.20 EAQ93132.1 - 0.045 13.4 0.0 0.088 12.4 0.0 1.5 1 0 0 1 1 1 0 Putative esterase MTD PF01993.18 EAQ93132.1 - 0.1 11.9 0.0 7.1 5.9 0.0 2.3 1 1 1 2 2 2 0 methylene-5,6,7,8-tetrahydromethanopterin dehydrogenase zf-RING_2 PF13639.6 EAQ93134.1 - 2.6e-12 46.9 6.3 4e-12 46.3 6.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EAQ93134.1 - 1.5e-08 34.3 6.2 2.4e-08 33.7 6.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EAQ93134.1 - 2e-08 33.8 1.0 3.4e-08 33.1 1.0 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 EAQ93134.1 - 8.5e-08 31.9 4.0 1.4e-07 31.3 4.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EAQ93134.1 - 2e-07 31.2 8.9 7.2e-07 29.4 8.9 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 EAQ93134.1 - 1.7e-06 27.9 3.6 2.7e-06 27.2 3.6 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EAQ93134.1 - 0.00027 20.9 4.5 0.00042 20.3 0.6 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 EAQ93134.1 - 0.00072 19.6 2.7 0.0014 18.7 2.7 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 EAQ93134.1 - 0.0024 17.7 2.4 0.0036 17.1 2.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) OAD_gamma PF04277.13 EAQ93134.1 - 0.019 15.5 0.3 0.28 11.8 0.0 2.9 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain zf-RING_4 PF14570.6 EAQ93134.1 - 0.032 14.0 6.3 0.054 13.3 6.3 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Zn_ribbon_17 PF17120.5 EAQ93134.1 - 0.09 12.4 4.8 0.16 11.6 4.8 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 EAQ93134.1 - 0.16 12.1 4.0 0.36 11.0 4.0 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING PHD PF00628.29 EAQ93134.1 - 0.18 11.8 5.6 0.31 11.0 5.6 1.4 1 0 0 1 1 1 0 PHD-finger FANCL_C PF11793.8 EAQ93134.1 - 0.3 11.3 3.1 0.83 9.9 3.1 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.7 EAQ93134.1 - 0.31 11.2 3.5 0.75 10.0 3.5 1.7 1 1 0 1 1 1 0 RING-variant domain Prok-RING_4 PF14447.6 EAQ93134.1 - 0.44 10.5 4.7 0.93 9.4 4.7 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Prok-RING_1 PF14446.6 EAQ93134.1 - 0.96 9.4 7.7 0.056 13.4 1.5 1.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 DUF3752 PF12572.8 EAQ93135.1 - 3.2e-48 164.1 6.1 6e-48 163.2 6.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3752) Vps8 PF12816.7 EAQ93136.1 - 1.7e-75 252.9 0.0 3.2e-75 252.0 0.0 1.5 1 0 0 1 1 1 1 Golgi CORVET complex core vacuolar protein 8 PIG-P PF08510.12 EAQ93136.1 - 1.6e-51 173.3 0.0 3.5e-51 172.2 0.0 1.6 1 0 0 1 1 1 1 PIG-P Clathrin PF00637.20 EAQ93136.1 - 2.7e-05 24.1 0.0 0.026 14.4 0.0 2.8 3 0 0 3 3 3 2 Region in Clathrin and VPS RhlB PF12300.8 EAQ93136.1 - 0.0087 16.2 3.8 0.0087 16.2 3.8 3.6 3 0 0 3 3 3 1 ATP-dependent RNA helicase RhlB CDC45 PF02724.14 EAQ93136.1 - 0.18 10.1 2.4 0.34 9.2 2.4 1.3 1 0 0 1 1 1 0 CDC45-like protein DPM2 PF07297.12 EAQ93136.1 - 0.85 10.0 11.3 2.1 8.7 11.3 1.6 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) SSP160 PF06933.11 EAQ93136.1 - 2.1 6.4 11.3 3.3 5.8 11.3 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Actin PF00022.19 EAQ93138.1 - 9.3e-144 479.0 0.0 1.1e-143 478.8 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.13 EAQ93138.1 - 3.8e-05 22.7 0.1 0.0071 15.2 0.0 2.1 2 0 0 2 2 2 2 MreB/Mbl protein D-ser_dehydrat PF14031.6 EAQ93139.1 - 3.8e-23 82.0 0.0 8.5e-23 80.8 0.0 1.6 1 0 0 1 1 1 1 Putative serine dehydratase domain Ala_racemase_N PF01168.20 EAQ93139.1 - 1.5e-07 31.3 0.0 3.3e-07 30.2 0.0 1.5 1 1 0 1 1 1 1 Alanine racemase, N-terminal domain DUF3591 PF12157.8 EAQ93140.1 - 3.8e-164 546.5 0.6 4.6e-164 546.3 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3591) zf-CCHC PF00098.23 EAQ93140.1 - 0.025 14.7 0.4 0.045 13.8 0.4 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_6 PF15288.6 EAQ93140.1 - 0.26 11.1 2.1 1.3 8.9 2.1 2.2 1 0 0 1 1 1 0 Zinc knuckle SRF-TF PF00319.18 EAQ93143.1 - 3.8e-24 83.9 0.2 5.8e-24 83.3 0.2 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) FRG1 PF06229.12 EAQ93144.1 - 5.3e-49 166.5 0.0 6.5e-49 166.2 0.0 1.1 1 0 0 1 1 1 1 FRG1-like domain Fascin PF06268.13 EAQ93144.1 - 0.038 14.2 0.0 0.094 12.9 0.0 1.7 2 0 0 2 2 2 0 Fascin domain 2OG-FeII_Oxy PF03171.20 EAQ93145.1 - 0.03 14.8 0.0 0.094 13.2 0.0 1.8 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 EAQ93145.1 - 0.043 14.6 0.0 0.079 13.7 0.0 1.4 1 0 0 1 1 1 0 non-haem dioxygenase in morphine synthesis N-terminal DUF4448 PF14610.6 EAQ93146.1 - 1.6e-42 145.5 0.0 1.9e-42 145.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Glyco_hydro_31 PF01055.26 EAQ93147.1 - 8.7e-94 315.2 0.8 1.3e-93 314.6 0.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 EAQ93147.1 - 6.8e-34 116.5 0.0 1.2e-33 115.7 0.0 1.4 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Sugar_tr PF00083.24 EAQ93148.1 - 1.5e-124 416.3 21.6 1.8e-124 416.1 21.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EAQ93148.1 - 2.1e-21 76.2 37.1 1e-16 60.9 14.4 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily Ilm1 PF10311.9 EAQ93148.1 - 0.053 13.2 0.0 0.088 12.5 0.0 1.5 1 1 0 1 1 1 0 Increased loss of mitochondrial DNA protein 1 7tm_1 PF00001.21 EAQ93148.1 - 0.11 11.8 4.7 0.99 8.7 1.4 2.5 2 0 0 2 2 2 0 7 transmembrane receptor (rhodopsin family) FAD_binding_2 PF00890.24 EAQ93149.1 - 1.8e-84 284.3 0.7 2.2e-84 284.0 0.7 1.1 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.28 EAQ93149.1 - 1.3e-21 76.5 0.1 2.5e-20 72.4 0.0 2.8 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.24 EAQ93149.1 - 1.3e-14 54.6 0.4 2.6e-14 53.6 0.4 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 EAQ93149.1 - 4.1e-10 39.6 0.6 2.1e-09 37.3 0.6 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EAQ93149.1 - 8.8e-09 35.5 2.7 1.6e-07 31.4 0.6 3.0 2 1 1 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EAQ93149.1 - 1.6e-06 27.5 0.3 2.2e-05 23.8 0.2 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EAQ93149.1 - 1.1e-05 24.9 0.0 0.14 11.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EAQ93149.1 - 1.3e-05 24.1 3.0 0.0086 14.8 0.2 3.3 3 0 0 3 3 3 2 HI0933-like protein Thi4 PF01946.17 EAQ93149.1 - 0.00015 21.1 1.1 0.03 13.6 0.3 2.4 2 0 0 2 2 2 2 Thi4 family Amino_oxidase PF01593.24 EAQ93149.1 - 0.0025 17.2 0.7 0.28 10.4 0.2 3.0 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.19 EAQ93149.1 - 0.0026 17.1 2.0 0.0049 16.1 2.0 1.5 1 1 0 1 1 1 1 FAD binding domain GIDA PF01134.22 EAQ93149.1 - 0.0082 15.3 4.6 0.16 11.1 1.3 2.7 3 0 0 3 3 3 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 EAQ93149.1 - 0.07 12.4 0.9 0.15 11.4 0.9 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 EAQ93149.1 - 0.62 10.7 4.3 4.9 7.8 1.6 2.9 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Sin3a_C PF16879.5 EAQ93150.1 - 1.7e-71 241.3 5.5 1.7e-71 241.3 5.5 2.1 3 0 0 3 3 3 1 C-terminal domain of Sin3a protein PAH PF02671.21 EAQ93150.1 - 1.3e-42 143.7 2.5 4.6e-18 65.1 3.2 3.8 3 1 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.12 EAQ93150.1 - 1.2e-39 134.3 0.4 3.2e-39 133.0 0.0 2.0 2 0 0 2 2 2 1 Sin3 family co-repressor Pollen_allerg_1 PF01357.21 EAQ93150.1 - 0.0084 16.1 0.3 0.24 11.4 0.4 2.5 2 0 0 2 2 2 1 Pollen allergen Fasciclin PF02469.22 EAQ93150.1 - 0.014 15.6 0.0 0.044 14.0 0.0 1.8 1 0 0 1 1 1 0 Fasciclin domain Lge1 PF11488.8 EAQ93150.1 - 0.15 12.3 1.1 0.64 10.3 0.2 2.4 2 0 0 2 2 2 0 Transcriptional regulatory protein LGE1 Chromate_transp PF02417.15 EAQ93151.1 - 9.3e-17 61.6 13.0 3.9e-16 59.6 13.0 1.8 1 1 0 1 1 1 1 Chromate transporter TMP_2 PF06791.13 EAQ93151.1 - 0.14 11.8 2.5 0.23 11.1 2.5 1.2 1 0 0 1 1 1 0 Prophage tail length tape measure protein Fungal_trans PF04082.18 EAQ93152.1 - 0.00097 18.2 0.1 0.0023 17.0 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain FeS_assembly_P PF01883.19 EAQ93153.1 - 3.6e-07 30.3 0.0 1.7e-06 28.1 0.0 2.0 1 1 0 1 1 1 1 Iron-sulfur cluster assembly protein GTP_EFTU PF00009.27 EAQ93154.1 - 3.7e-47 160.4 0.0 5.4e-47 159.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFTUD2 PF16004.5 EAQ93154.1 - 4.8e-36 124.0 6.1 1e-35 123.0 6.1 1.6 1 0 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_C PF00679.24 EAQ93154.1 - 9.8e-19 67.2 0.0 3.4e-18 65.4 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G C-terminus EFG_IV PF03764.18 EAQ93154.1 - 9.9e-16 57.6 0.0 2.6e-15 56.3 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV GTP_EFTU_D2 PF03144.25 EAQ93154.1 - 2.4e-10 40.7 0.2 5.7e-10 39.5 0.2 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 EAQ93154.1 - 1e-06 28.7 0.0 2.3e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 EAQ93154.1 - 5.6e-06 26.4 0.1 1.2e-05 25.4 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Thiolase_N PF00108.23 EAQ93155.1 - 1.4e-88 296.6 0.9 2.7e-88 295.7 0.9 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EAQ93155.1 - 4.1e-47 158.9 0.3 1e-46 157.6 0.3 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EAQ93155.1 - 4.8e-05 23.1 1.2 0.00012 21.7 0.7 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 EAQ93155.1 - 0.019 14.8 5.3 0.072 13.0 0.1 2.8 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Sel1 PF08238.12 EAQ93156.1 - 9.7e-38 127.8 44.2 7.8e-07 29.6 1.3 12.2 12 1 1 13 13 13 10 Sel1 repeat LapA_dom PF06305.11 EAQ93156.1 - 4.4 7.2 5.2 1.6 8.6 2.1 1.8 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Fer2_3 PF13085.6 EAQ93157.1 - 1.1e-33 115.5 0.0 1.6e-33 114.9 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2 PF00111.27 EAQ93157.1 - 0.0017 18.3 0.2 0.0035 17.3 0.2 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain SF3a60_bindingd PF12108.8 EAQ93157.1 - 0.1 12.5 0.4 0.17 11.8 0.4 1.4 1 0 0 1 1 1 0 Splicing factor SF3a60 binding domain FTCD_C PF04961.12 EAQ93158.1 - 0.84 9.4 3.0 0.63 9.8 0.2 1.9 2 0 0 2 2 2 0 Formiminotransferase-cyclodeaminase WD40 PF00400.32 EAQ93161.1 - 8.7e-36 121.3 22.4 1.7e-08 34.9 1.2 6.9 6 1 0 6 6 6 5 WD domain, G-beta repeat PRP4 PF08799.11 EAQ93161.1 - 2.5e-15 55.7 2.2 4.1e-15 55.0 2.2 1.4 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like ANAPC4_WD40 PF12894.7 EAQ93161.1 - 1.2e-11 44.7 0.7 0.057 13.7 0.0 5.6 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EAQ93161.1 - 0.0084 16.0 0.0 2.3 8.1 0.0 2.6 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 EAQ93161.1 - 0.014 14.4 0.0 12 4.8 0.0 3.2 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 EAQ93161.1 - 0.026 13.8 0.0 7.4 5.8 0.0 3.0 3 0 0 3 3 3 0 WD40-like domain Pkinase PF00069.25 EAQ93162.1 - 3.1e-69 233.3 0.0 3.9e-69 233.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ93162.1 - 9.8e-30 103.7 0.0 1.3e-29 103.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EAQ93162.1 - 0.0025 16.8 0.1 0.0037 16.3 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EAQ93162.1 - 0.0067 15.8 0.1 0.016 14.5 0.0 1.6 1 1 1 2 2 2 1 Kinase-like FTA2 PF13095.6 EAQ93162.1 - 0.015 14.9 0.0 0.46 10.1 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 EAQ93162.1 - 0.039 12.7 0.5 0.073 11.8 0.5 1.5 1 1 0 1 1 1 0 Fungal protein kinase APH PF01636.23 EAQ93162.1 - 0.073 13.0 0.3 2.4 8.0 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family ATP_sub_h PF10775.9 EAQ93163.1 - 3.4e-26 91.0 0.8 5.1e-26 90.5 0.8 1.3 1 0 0 1 1 1 1 ATP synthase complex subunit h Pkinase PF00069.25 EAQ93164.1 - 1.9e-68 230.7 0.0 2.5e-68 230.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ93164.1 - 2e-31 109.2 0.0 2.9e-31 108.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 EAQ93164.1 - 3.5e-14 53.2 0.6 1.1e-13 51.6 0.6 2.0 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 EAQ93164.1 - 9.4e-10 38.3 0.0 3.8e-09 36.3 0.0 1.8 1 1 0 2 2 2 1 Kinase-like C2 PF00168.30 EAQ93164.1 - 3.5e-08 33.7 0.0 7.8e-05 22.9 0.0 2.5 2 0 0 2 2 2 2 C2 domain Haspin_kinase PF12330.8 EAQ93164.1 - 0.0012 17.9 0.4 0.0029 16.6 0.1 1.6 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 EAQ93164.1 - 0.0076 15.6 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Adeno_E3_15_3 PF03307.14 EAQ93164.1 - 0.011 15.7 0.0 0.021 14.8 0.0 1.4 1 0 0 1 1 1 0 Adenovirus 15.3kD protein in E3 region Pkinase_fungal PF17667.1 EAQ93164.1 - 0.012 14.4 0.0 0.23 10.2 0.0 2.2 2 0 0 2 2 2 0 Fungal protein kinase FTA2 PF13095.6 EAQ93164.1 - 0.026 14.2 0.2 6.6 6.3 0.1 2.5 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 EAQ93164.1 - 0.04 13.8 0.0 0.077 12.9 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 EAQ93164.1 - 0.047 13.3 0.1 0.076 12.6 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase SUZ PF12752.7 EAQ93167.1 - 9.8e-05 23.0 7.5 9.8e-05 23.0 7.5 3.2 2 1 1 3 3 3 1 SUZ domain Spore_III_AF PF09581.10 EAQ93167.1 - 0.027 14.5 0.3 0.043 13.8 0.3 1.2 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) U1snRNP70_N PF12220.8 EAQ93167.1 - 0.079 13.6 10.8 0.056 14.1 3.8 2.2 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal EMC3_TMCO1 PF01956.16 EAQ93167.1 - 0.84 9.4 1.8 1.6 8.5 1.8 1.4 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Fe_hyd_lg_C PF02906.14 EAQ93168.1 - 1.9e-50 171.8 0.0 4.7e-50 170.5 0.0 1.6 1 1 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain zf-H2C2_2 PF13465.6 EAQ93170.1 - 2.2e-07 31.0 3.2 2.8e-06 27.5 1.1 2.4 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.26 EAQ93170.1 - 5.1e-07 29.8 2.7 2.1e-05 24.7 0.3 2.4 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 EAQ93170.1 - 1.7e-05 24.7 0.5 0.052 13.6 0.0 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_4 PF13894.6 EAQ93170.1 - 0.00047 20.8 3.0 0.01 16.6 0.3 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_11 PF16622.5 EAQ93170.1 - 0.18 11.6 0.3 0.45 10.3 0.0 1.8 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-H2C2_5 PF13909.6 EAQ93170.1 - 0.4 10.5 1.9 1.9 8.3 0.0 2.3 2 0 0 2 2 2 0 C2H2-type zinc-finger domain MPDZ_u10 PF16667.5 EAQ93170.1 - 6.7 7.7 8.5 9 7.3 4.7 2.6 2 0 0 2 2 2 0 Unstructured region 10 on multiple PDZ protein LRR_6 PF13516.6 EAQ93171.1 - 8.7e-10 37.9 15.6 0.00013 21.7 0.0 6.8 7 0 0 7 7 7 2 Leucine Rich repeat LRR_4 PF12799.7 EAQ93171.1 - 6.3e-07 29.6 15.5 0.091 13.2 0.0 6.2 6 1 0 6 6 6 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EAQ93171.1 - 5.2e-05 22.9 13.1 0.56 10.0 0.1 5.2 4 1 0 4 4 4 2 Leucine rich repeat LRR_1 PF00560.33 EAQ93171.1 - 0.00017 21.6 1.5 11 7.0 0.1 5.5 5 0 0 5 5 5 1 Leucine Rich Repeat Lin-8 PF03353.15 EAQ93171.1 - 0.88 9.1 8.0 1.3 8.5 8.0 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Glyco_hydro_18 PF00704.28 EAQ93172.1 - 1.1e-70 238.8 0.0 1.4e-70 238.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF5580 PF17743.1 EAQ93174.1 - 0.071 11.6 0.9 0.12 10.9 0.9 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5580) HWE_HK PF07536.14 EAQ93174.1 - 0.093 13.4 0.0 0.67 10.7 0.0 2.2 2 0 0 2 2 2 0 HWE histidine kinase Cmc1 PF08583.10 EAQ93174.1 - 0.52 10.4 9.0 0.04 13.9 3.1 2.2 2 1 0 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.13 EAQ93174.1 - 0.65 10.2 4.7 9.1 6.5 0.4 2.4 2 0 0 2 2 2 0 CHCH domain CX9C PF16860.5 EAQ93174.1 - 0.93 9.6 3.1 12 6.0 0.1 2.4 2 0 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Ank_2 PF12796.7 EAQ93176.1 - 1.4e-28 99.3 0.7 5.8e-08 33.2 0.5 3.8 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAQ93176.1 - 7.5e-26 90.2 7.6 4.8e-07 30.2 0.3 7.0 2 2 5 7 7 7 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAQ93176.1 - 3.4e-24 84.6 13.1 1.2e-11 44.6 0.2 5.9 3 2 3 6 6 6 3 Ankyrin repeats (many copies) Ank PF00023.30 EAQ93176.1 - 7.2e-21 73.7 19.2 0.0018 18.6 0.1 7.3 7 0 0 7 7 7 7 Ankyrin repeat Ank_3 PF13606.6 EAQ93176.1 - 4.6e-19 66.5 8.9 0.0013 19.0 0.2 8.0 7 1 0 7 7 7 4 Ankyrin repeat Helo_like_N PF17111.5 EAQ93177.1 - 2.6e-18 66.2 2.4 4.6e-18 65.4 2.2 1.5 1 1 0 1 1 1 1 Fungal N-terminal domain of STAND proteins SesA PF17107.5 EAQ93177.1 - 0.00082 19.6 0.1 0.00082 19.6 0.1 2.6 1 1 1 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases TMV_coat PF00721.21 EAQ93177.1 - 0.04 13.7 4.5 0.087 12.7 4.5 1.6 1 0 0 1 1 1 0 Virus coat protein (TMV like) Ses_B PF17046.5 EAQ93177.1 - 0.051 13.5 0.5 0.12 12.4 0.5 1.7 1 0 0 1 1 1 0 SesB domain on fungal death-pathway protein TraG_N PF07916.11 EAQ93177.1 - 0.055 12.3 4.8 0.072 11.9 4.8 1.1 1 0 0 1 1 1 0 TraG-like protein, N-terminal region CutA1 PF03091.15 EAQ93177.1 - 0.068 13.0 0.3 0.19 11.6 0.3 1.8 1 0 0 1 1 1 0 CutA1 divalent ion tolerance protein AnfO_nitrog PF09582.10 EAQ93177.1 - 0.097 12.0 2.0 0.14 11.5 1.8 1.4 1 1 0 1 1 1 0 Iron only nitrogenase protein AnfO (AnfO_nitrog) YbjQ_1 PF01906.17 EAQ93177.1 - 0.21 12.2 2.1 4.8 7.9 0.7 2.8 2 1 0 2 2 2 0 Putative heavy-metal-binding FH2 PF02181.23 EAQ93177.1 - 0.33 10.0 6.0 3.2 6.8 6.1 2.0 1 1 1 2 2 2 0 Formin Homology 2 Domain FUSC PF04632.12 EAQ93177.1 - 0.64 8.5 11.1 1 7.8 11.1 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF4407 PF14362.6 EAQ93177.1 - 0.69 9.2 10.4 1.1 8.5 10.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CR6_interact PF10147.9 EAQ93177.1 - 0.79 9.4 7.7 0.11 12.1 1.3 2.1 1 1 1 2 2 2 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 DUF4665 PF15679.5 EAQ93177.1 - 0.81 10.3 3.6 1.1 9.9 0.4 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4665) HAUS-augmin3 PF14932.6 EAQ93177.1 - 1.2 8.7 11.0 2.6 7.6 11.0 1.5 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF745 PF05335.13 EAQ93177.1 - 1.3 8.7 19.8 28 4.4 19.4 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF745) COG5 PF10392.9 EAQ93177.1 - 1.5 9.0 10.4 0.43 10.7 4.7 2.6 2 1 1 3 3 3 0 Golgi transport complex subunit 5 Phage_GPO PF05929.11 EAQ93177.1 - 1.7 8.2 9.9 2.7 7.5 9.9 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Phage_holin_7_1 PF16081.5 EAQ93177.1 - 2 8.6 10.6 0.52 10.5 5.1 2.5 1 1 1 3 3 3 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family DUF2203 PF09969.9 EAQ93177.1 - 4 8.2 10.0 1.1e+02 3.5 0.6 3.1 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) AIP3 PF03915.13 EAQ93177.1 - 6.7 5.7 11.1 3.4 6.7 8.2 1.9 2 1 0 2 2 2 0 Actin interacting protein 3 AATF-Che1 PF13339.6 EAQ93177.1 - 7 7.3 9.7 10 6.8 8.2 2.0 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor Hrs_helical PF12210.8 EAQ93177.1 - 9.5 6.8 12.9 3.4e+02 1.9 0.1 3.4 2 1 0 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate CAF1A PF12253.8 EAQ93178.1 - 1.8 8.8 6.8 2.2 8.5 0.1 2.3 2 0 0 2 2 2 0 Chromatin assembly factor 1 subunit A TPR_12 PF13424.6 EAQ93179.1 - 6.5e-38 128.9 7.6 2.7e-12 46.8 0.3 6.5 3 2 4 7 7 7 5 Tetratricopeptide repeat TPR_10 PF13374.6 EAQ93179.1 - 1.9e-35 119.8 8.4 2.5e-09 36.7 0.0 8.3 7 1 1 8 8 8 6 Tetratricopeptide repeat TPR_7 PF13176.6 EAQ93179.1 - 1.6e-10 40.3 7.8 0.14 12.2 0.1 7.6 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_8 PF13181.6 EAQ93179.1 - 3.9e-08 32.9 5.7 1.1 9.6 0.0 6.6 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_4 PF07721.14 EAQ93179.1 - 1.2e-06 28.6 5.4 15 6.5 0.0 7.5 7 1 1 8 8 7 0 Tetratricopeptide repeat TPR_2 PF07719.17 EAQ93179.1 - 2.1e-06 27.4 17.1 0.62 10.3 0.0 7.7 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_1 PF00515.28 EAQ93179.1 - 1.8e-05 24.3 11.3 0.33 10.9 0.0 6.0 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_MalT PF17874.1 EAQ93179.1 - 5.6e-05 22.7 8.1 0.01 15.3 0.2 3.7 1 1 1 3 3 3 2 MalT-like TPR region TPR_19 PF14559.6 EAQ93179.1 - 0.00019 21.9 4.2 3.3 8.3 0.0 5.7 4 2 3 7 7 7 1 Tetratricopeptide repeat TPR_14 PF13428.6 EAQ93179.1 - 0.0013 19.4 11.3 11 7.2 0.0 7.6 8 1 1 9 9 8 1 Tetratricopeptide repeat TPR_17 PF13431.6 EAQ93179.1 - 0.0023 18.2 1.1 72 4.1 0.0 6.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 EAQ93179.1 - 3.6 8.4 15.9 9.9 7.0 0.1 6.3 8 0 0 8 8 7 0 Tetratricopeptide repeat RVT_1 PF00078.27 EAQ93180.1 - 7.1e-33 114.0 0.0 1.1e-32 113.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ER_lumen_recept PF00810.18 EAQ93181.1 - 1.2e-39 136.5 14.3 1.7e-39 136.0 14.3 1.2 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.14 EAQ93181.1 - 0.054 13.3 0.2 0.054 13.3 0.2 3.0 4 0 0 4 4 4 0 PQ loop repeat DUF1516 PF07457.11 EAQ93181.1 - 0.055 13.7 0.4 0.055 13.7 0.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1516) NUP214 PF16755.5 EAQ93182.1 - 0.00011 21.6 0.0 0.00018 20.9 0.0 1.2 1 0 0 1 1 1 1 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 ANAPC4_WD40 PF12894.7 EAQ93182.1 - 0.01 16.1 0.0 0.038 14.3 0.0 1.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Na_trans_assoc PF06512.13 EAQ93182.1 - 0.45 10.8 6.2 0.98 9.7 6.2 1.5 1 0 0 1 1 1 0 Sodium ion transport-associated Proteasome PF00227.26 EAQ93183.1 - 2.8e-46 157.4 0.3 3.6e-46 157.1 0.3 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.8 EAQ93183.1 - 4.3e-12 45.2 0.0 4.3e-12 45.2 0.0 1.7 2 0 0 2 2 2 1 Proteasome beta subunits C terminal Sel1 PF08238.12 EAQ93184.1 - 4.6e-12 46.2 8.5 0.00048 20.7 0.0 3.7 4 0 0 4 4 4 3 Sel1 repeat COPIIcoated_ERV PF07970.12 EAQ93185.1 - 9.7e-77 257.7 0.0 2.7e-76 256.3 0.0 1.7 1 1 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 EAQ93185.1 - 3.8e-31 107.3 0.0 1.1e-30 105.8 0.0 1.8 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Acetyltransf_3 PF13302.7 EAQ93186.1 - 4.7e-16 59.7 0.0 5.6e-16 59.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EAQ93186.1 - 0.056 13.7 0.0 0.084 13.1 0.0 1.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family Per1 PF04080.13 EAQ93187.1 - 3.4e-100 335.0 9.8 4e-100 334.8 9.8 1.0 1 0 0 1 1 1 1 Per1-like family MerC PF03203.14 EAQ93187.1 - 1.3 9.5 11.1 0.32 11.5 5.6 2.4 1 1 1 2 2 2 0 MerC mercury resistance protein Ppx-GppA PF02541.16 EAQ93190.1 - 1.6e-24 86.8 0.0 3.7e-23 82.4 0.0 2.1 1 1 0 1 1 1 1 Ppx/GppA phosphatase family TOPRIM_C PF16898.5 EAQ93192.1 - 0.054 13.8 0.3 0.11 12.8 0.3 1.4 1 0 0 1 1 1 0 C-terminal associated domain of TOPRIM Metallophos PF00149.28 EAQ93194.1 - 1.7e-10 41.8 0.1 2.2e-10 41.4 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EAQ93194.1 - 5.6e-06 26.6 0.5 0.00022 21.5 0.5 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain RCR PF12273.8 EAQ93195.1 - 3.5e-24 85.8 11.4 5.3e-24 85.2 11.4 1.3 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red Ribosomal_S9 PF00380.19 EAQ93196.1 - 1.9e-30 105.9 0.2 2.2e-30 105.7 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Arf PF00025.21 EAQ93197.1 - 7.2e-43 146.0 0.0 8.6e-43 145.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 EAQ93197.1 - 1.4e-18 67.0 0.0 1.6e-18 66.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAQ93197.1 - 5.6e-14 52.4 0.0 9.4e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 EAQ93197.1 - 1.8e-07 30.7 0.0 2.2e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 EAQ93197.1 - 4.9e-06 26.0 0.0 2.5e-05 23.6 0.0 2.2 1 1 1 2 2 2 1 G-protein alpha subunit MMR_HSR1 PF01926.23 EAQ93197.1 - 6.1e-06 26.3 0.0 9.4e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 EAQ93197.1 - 0.00012 21.6 0.0 0.00015 21.2 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 EAQ93197.1 - 0.017 14.7 0.2 0.043 13.3 0.2 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B DUF1979 PF09322.10 EAQ93197.1 - 0.067 13.1 0.2 9.8 6.2 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1979) MMR_HSR1_Xtn PF16897.5 EAQ93197.1 - 0.14 12.1 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain RNA_pol_Rpb2_6 PF00562.28 EAQ93198.1 - 1.8e-112 376.2 0.0 2.4e-112 375.9 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_3 PF04565.16 EAQ93198.1 - 2.1e-28 98.3 0.0 4.2e-28 97.3 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_2 PF04561.14 EAQ93198.1 - 3.3e-24 85.6 0.0 5.2e-24 84.9 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpa2_4 PF06883.12 EAQ93198.1 - 3.5e-24 84.6 0.0 7.7e-24 83.5 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_1 PF04563.15 EAQ93198.1 - 5.7e-20 71.7 0.0 4.2e-19 68.9 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 EAQ93198.1 - 1.1e-15 57.8 0.0 4.3e-14 52.7 0.0 2.6 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 7 Tyrosinase PF00264.20 EAQ93199.1 - 8.3e-53 179.9 0.9 1.3e-52 179.3 0.9 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase Tyosinase_C PF18132.1 EAQ93199.1 - 4.1e-26 92.1 0.0 7.7e-26 91.2 0.0 1.5 1 0 0 1 1 1 1 Tyosinase C-terminal domain STIMATE PF12400.8 EAQ93200.1 - 1e-41 142.4 3.9 1.7e-41 141.7 3.9 1.3 1 0 0 1 1 1 1 STIMATE family RRM_1 PF00076.22 EAQ93201.1 - 4.3e-19 68.1 0.3 8.4e-19 67.2 0.1 1.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EAQ93201.1 - 1.3e-06 28.0 0.0 1.4e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EAQ93201.1 - 0.00097 18.9 0.0 0.0013 18.5 0.0 1.2 1 0 0 1 1 1 1 Occluded RNA-recognition motif Frankia_peptide PF14407.6 EAQ93201.1 - 0.0096 15.9 0.1 2.1 8.4 0.0 2.9 2 1 1 3 3 3 1 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. RRM_8 PF11835.8 EAQ93201.1 - 0.037 14.2 0.0 0.047 13.9 0.0 1.2 1 0 0 1 1 1 0 RRM-like domain Tsc35 PF15079.6 EAQ93202.1 - 0.43 10.1 1.5 0.72 9.4 1.5 1.3 1 0 0 1 1 1 0 Testis-specific protein 35 zf-UDP PF14569.6 EAQ93202.1 - 1.4 9.1 8.1 0.54 10.4 1.3 2.5 2 0 0 2 2 2 0 Zinc-binding RING-finger zf-C3HC4 PF00097.25 EAQ93202.1 - 9.6 6.2 12.8 3 7.8 5.6 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) AAA PF00004.29 EAQ93203.1 - 1.1e-30 106.8 0.0 2e-30 105.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EAQ93203.1 - 1.8e-07 30.8 0.0 4.7e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 EAQ93203.1 - 7.7e-05 22.7 0.0 0.00048 20.1 0.0 2.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EAQ93203.1 - 0.00017 21.9 0.0 0.0034 17.7 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.14 EAQ93203.1 - 0.00026 21.2 0.0 0.00077 19.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 EAQ93203.1 - 0.00051 20.5 0.1 0.011 16.1 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 EAQ93203.1 - 0.002 17.4 0.0 0.0035 16.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 EAQ93203.1 - 0.0074 16.0 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 EAQ93203.1 - 0.017 14.9 0.1 0.19 11.4 0.1 2.6 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EAQ93203.1 - 0.019 15.2 0.0 0.054 13.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EAQ93203.1 - 0.043 14.2 0.0 0.14 12.6 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.6 EAQ93203.1 - 0.044 13.9 0.0 0.083 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EAQ93203.1 - 0.056 12.9 0.0 0.16 11.5 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region ATPase_2 PF01637.18 EAQ93203.1 - 0.065 13.1 0.9 11 5.9 0.0 2.9 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea AAA_3 PF07726.11 EAQ93203.1 - 0.072 13.0 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 EAQ93203.1 - 0.11 12.5 0.0 0.27 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 EAQ93203.1 - 0.12 11.8 0.0 0.35 10.2 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 EAQ93203.1 - 0.13 12.8 0.0 0.41 11.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain Cpn60_TCP1 PF00118.24 EAQ93204.1 - 2.7e-148 494.7 16.6 3e-148 494.5 16.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Phage_tail_X PF05489.12 EAQ93204.1 - 0.12 12.1 0.0 0.3 10.8 0.0 1.6 1 0 0 1 1 1 0 Phage Tail Protein X DUF3599 PF12206.8 EAQ93204.1 - 0.16 12.3 0.1 0.35 11.2 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3599) DUF3546 PF12066.8 EAQ93205.1 - 2.1e-33 114.8 4.5 2.1e-33 114.8 4.5 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3546) DUF4187 PF13821.6 EAQ93205.1 - 7.9e-12 44.8 0.1 2e-11 43.5 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) ARS2 PF04959.13 EAQ93205.1 - 1.7e-06 28.6 13.0 7.7e-06 26.4 12.8 2.3 1 1 0 1 1 1 1 Arsenite-resistance protein 2 PEP-utilisers_N PF05524.13 EAQ93205.1 - 1.6 8.9 5.0 2.1 8.6 0.4 2.7 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal OmpH PF03938.14 EAQ93205.1 - 8.6 6.7 12.9 17 5.8 5.2 2.4 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Mito_carr PF00153.27 EAQ93207.1 - 7.7e-59 195.6 0.0 1.5e-20 72.9 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF2292 PF10055.9 EAQ93207.1 - 0.25 11.0 0.2 0.43 10.3 0.2 1.3 1 0 0 1 1 1 0 Uncharacterized small protein (DUF2292) DEAD PF00270.29 EAQ93209.1 - 2e-47 161.2 0.0 3e-46 157.4 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EAQ93209.1 - 1.3e-27 96.4 0.0 4.9e-27 94.5 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EAQ93209.1 - 0.00015 21.8 0.0 0.0004 20.4 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF3334 PF11813.8 EAQ93209.1 - 0.0027 17.5 0.2 0.016 15.0 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3334) PRAI PF00697.22 EAQ93209.1 - 0.15 11.8 0.1 0.28 10.9 0.1 1.4 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase Mitoc_mL59 PF18126.1 EAQ93210.1 - 4.9e-38 130.4 1.1 4.9e-38 130.4 1.1 1.8 2 0 0 2 2 2 1 Mitochondrial ribosomal protein mL59 zf-CSL PF05207.13 EAQ93210.1 - 5.3e-17 61.3 1.2 8e-17 60.7 1.2 1.3 1 0 0 1 1 1 1 CSL zinc finger DnaJ PF00226.31 EAQ93210.1 - 1.3e-11 44.4 1.3 1.2e-10 41.3 1.3 2.3 1 1 0 1 1 1 1 DnaJ domain 14-3-3 PF00244.20 EAQ93211.1 - 8.7e-107 355.7 4.8 1e-106 355.5 4.8 1.0 1 0 0 1 1 1 1 14-3-3 protein TPR_19 PF14559.6 EAQ93211.1 - 0.22 12.0 3.3 0.74 10.4 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Alpha-L-AF_C PF06964.12 EAQ93212.1 - 2.3e-21 76.7 0.1 1.2e-20 74.4 0.1 2.1 1 1 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain CBM_4_9 PF02018.17 EAQ93212.1 - 0.00013 22.3 0.1 0.00029 21.1 0.1 1.6 1 0 0 1 1 1 1 Carbohydrate binding domain MFS_1 PF07690.16 EAQ93214.1 - 8.1e-25 87.5 36.7 4.2e-24 85.1 35.5 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EAQ93214.1 - 5.8e-15 55.1 4.2 5.8e-15 55.1 4.2 1.6 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 EAQ93214.1 - 0.00096 18.5 27.1 0.0016 17.8 9.5 3.2 2 1 1 3 3 3 3 Uncharacterised MFS-type transporter YbfB VIR_N PF15912.5 EAQ93214.1 - 0.037 13.6 2.4 0.072 12.7 2.4 1.4 1 0 0 1 1 1 0 Virilizer, N-terminal DUF3578 PF12102.8 EAQ93214.1 - 0.23 11.0 0.7 0.39 10.3 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3578) PRIMA1 PF16101.5 EAQ93214.1 - 1.3 9.1 7.9 4.5 7.3 7.9 1.9 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 MULE PF10551.9 EAQ93215.1 - 2.3e-28 98.4 0.1 4.1e-28 97.6 0.1 1.4 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.18 EAQ93215.1 - 1e-06 27.9 0.0 1.6e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Transposase, Mutator family DDE_Tnp_ISL3 PF01610.17 EAQ93215.1 - 0.12 12.1 0.5 0.28 10.9 0.5 1.6 1 1 0 1 1 1 0 Transposase Glyco_hydro_12 PF01670.16 EAQ93216.1 - 9e-54 182.7 4.8 1.3e-53 182.2 4.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 adh_short PF00106.25 EAQ93216.1 - 5.5e-17 61.9 0.0 1.3e-16 60.6 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EAQ93216.1 - 3.7e-16 59.4 0.0 6.1e-16 58.7 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EAQ93216.1 - 2.6e-06 27.5 0.0 4.6e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 KR domain MULE PF10551.9 EAQ93217.1 - 5.4e-24 84.4 0.0 9.4e-24 83.7 0.0 1.4 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.18 EAQ93217.1 - 0.00058 18.8 0.0 0.0011 18.0 0.0 1.3 1 0 0 1 1 1 1 Transposase, Mutator family IATP PF04568.12 EAQ93218.1 - 1.2e-30 105.9 2.0 1.3e-30 105.7 2.0 1.0 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP DUF489 PF04356.12 EAQ93218.1 - 0.026 14.6 0.5 0.034 14.1 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF489) NPV_P10 PF05531.12 EAQ93218.1 - 0.063 13.7 1.0 0.096 13.2 1.0 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF2205 PF10224.9 EAQ93218.1 - 0.083 12.9 5.4 0.12 12.4 5.4 1.2 1 0 0 1 1 1 0 Short coiled-coil protein DUF1003 PF06210.11 EAQ93218.1 - 0.092 12.9 1.9 0.14 12.3 1.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1003) IKKbetaNEMObind PF12179.8 EAQ93218.1 - 0.11 12.6 0.2 0.2 11.7 0.2 1.4 1 0 0 1 1 1 0 I-kappa-kinase-beta NEMO binding domain DivIC PF04977.15 EAQ93218.1 - 0.17 11.7 4.0 0.29 10.9 4.0 1.4 1 0 0 1 1 1 0 Septum formation initiator FlaC_arch PF05377.11 EAQ93218.1 - 0.36 11.3 1.6 0.58 10.6 1.6 1.2 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Nsp1_C PF05064.13 EAQ93219.1 - 1.8e-43 147.0 0.3 3.8e-43 146.0 0.3 1.5 1 0 0 1 1 1 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.6 EAQ93219.1 - 9.2e-10 39.2 140.3 0.12 13.3 42.5 6.0 1 1 3 4 4 3 3 Nucleoporin FG repeat region DUF948 PF06103.11 EAQ93219.1 - 0.076 13.3 0.4 0.41 10.9 0.0 2.2 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF812 PF05667.11 EAQ93219.1 - 0.15 10.9 2.1 0.24 10.3 0.7 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF812) EzrA PF06160.12 EAQ93219.1 - 0.23 9.6 4.0 2.6 6.1 1.7 2.0 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA MIP-T3_C PF17749.1 EAQ93219.1 - 0.27 11.2 0.1 0.27 11.2 0.1 2.4 3 0 0 3 3 3 0 Microtubule-binding protein MIP-T3 C-terminal region DUF4200 PF13863.6 EAQ93219.1 - 0.35 11.3 6.2 2.3 8.6 3.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) HIP1_clath_bdg PF16515.5 EAQ93219.1 - 0.65 10.6 2.7 14 6.3 1.3 2.4 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 ATG16 PF08614.11 EAQ93219.1 - 1 9.6 6.5 0.94 9.7 2.6 2.3 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) V-SNARE PF05008.15 EAQ93219.1 - 1.4 9.3 3.2 7.2 7.1 0.1 2.9 3 0 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus OmpH PF03938.14 EAQ93219.1 - 1.9 8.8 7.9 23 5.3 3.5 2.6 1 1 2 3 3 3 0 Outer membrane protein (OmpH-like) DUF4407 PF14362.6 EAQ93219.1 - 3.2 7.0 6.6 0.84 8.9 3.2 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) TPR_MLP1_2 PF07926.12 EAQ93219.1 - 8.8 6.4 7.7 2.8 8.0 5.0 1.5 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF5102 PF17104.5 EAQ93220.1 - 1.1e-96 324.3 0.1 5e-96 322.1 0.1 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF5102) eIF2_C PF09173.11 EAQ93221.1 - 5.7e-35 119.4 0.5 1.3e-34 118.3 0.5 1.6 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 EAQ93221.1 - 3.5e-22 78.9 1.2 3.6e-21 75.6 1.2 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 EAQ93221.1 - 7.8e-10 39.0 0.1 1.7e-09 37.9 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EAQ93221.1 - 0.0037 17.3 0.0 0.0078 16.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase ProQ_C PF17516.2 EAQ93221.1 - 0.0039 16.6 1.9 0.009 15.4 1.9 1.6 1 0 0 1 1 1 1 ProQ C-terminal domain MMR_HSR1_Xtn PF16897.5 EAQ93221.1 - 0.01 15.8 1.1 0.034 14.2 0.1 2.2 2 0 0 2 2 2 0 C-terminal region of MMR_HSR1 domain RsgA_GTPase PF03193.16 EAQ93221.1 - 0.043 13.7 0.2 0.49 10.3 0.1 2.2 2 0 0 2 2 2 0 RsgA GTPase Vpu PF00558.19 EAQ93223.1 - 2.5 7.9 4.3 5.1 6.9 1.4 2.3 2 0 0 2 2 2 0 Vpu protein ADK PF00406.22 EAQ93224.1 - 1.6e-44 151.7 0.0 2.2e-44 151.2 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EAQ93224.1 - 7.7e-35 120.3 0.0 1.1e-34 119.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EAQ93224.1 - 2.7e-06 28.0 0.0 4.6e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EAQ93224.1 - 0.00045 20.4 0.4 0.0023 18.1 0.0 2.3 2 1 0 2 2 2 1 AAA domain Thymidylate_kin PF02223.17 EAQ93224.1 - 0.0014 18.3 0.1 0.13 12.0 0.0 2.2 2 0 0 2 2 2 2 Thymidylate kinase PCI PF01399.27 EAQ93225.1 - 4e-14 53.0 0.3 2e-13 50.7 0.1 2.1 2 0 0 2 2 2 1 PCI domain eIF3m_C_helix PF18005.1 EAQ93225.1 - 3.7e-05 23.3 0.2 3.7e-05 23.3 0.2 1.9 2 0 0 2 2 2 1 eIF3 subunit M, C-terminal helix Pkinase PF00069.25 EAQ93226.1 - 3.1e-74 249.7 0.0 4e-74 249.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ93226.1 - 1.2e-36 126.3 0.0 1.6e-36 125.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 EAQ93226.1 - 3.9e-15 56.0 0.2 7.8e-15 55.0 0.2 1.5 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.6 EAQ93226.1 - 1.8e-10 40.6 0.0 2.4e-08 33.6 0.0 2.1 2 0 0 2 2 2 2 Kinase-like Yop-YscD_cpl PF16697.5 EAQ93226.1 - 7.7e-08 32.5 0.0 1.6e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain FHA_2 PF17913.1 EAQ93226.1 - 0.0001 22.5 0.0 0.00021 21.5 0.0 1.4 1 0 0 1 1 1 1 FHA domain Pkinase_fungal PF17667.1 EAQ93226.1 - 0.00023 20.1 0.0 0.00039 19.3 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EAQ93226.1 - 0.0049 16.2 0.0 0.0082 15.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 EAQ93226.1 - 0.013 14.4 0.0 0.02 13.9 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase ADH_zinc_N_2 PF13602.6 EAQ93227.1 - 6.9e-15 56.3 0.0 1.5e-14 55.2 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EAQ93227.1 - 6.8e-14 52.0 0.0 1.2e-13 51.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EAQ93227.1 - 0.00016 21.5 0.8 0.00057 19.7 0.4 2.0 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Dimer_Tnp_hAT PF05699.14 EAQ93229.1 - 3.2e-13 49.3 0.1 7.5e-13 48.1 0.1 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region p450 PF00067.22 EAQ93230.1 - 1.7e-25 89.7 0.0 1.6e-21 76.6 0.0 3.0 2 1 0 3 3 3 3 Cytochrome P450 ArfGap PF01412.18 EAQ93231.1 - 2.9e-33 114.4 1.6 4.2e-33 113.9 0.0 2.2 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf BAR_3 PF16746.5 EAQ93231.1 - 1.7e-21 77.0 17.9 2.8e-21 76.3 17.9 1.2 1 0 0 1 1 1 1 BAR domain of APPL family PH PF00169.29 EAQ93231.1 - 1.9e-13 50.8 0.1 8.9e-13 48.7 0.1 2.2 1 0 0 1 1 1 1 PH domain MamL-1 PF09596.10 EAQ93231.1 - 0.044 14.0 0.0 0.15 12.3 0.0 2.0 1 0 0 1 1 1 0 MamL-1 domain PilJ PF13675.6 EAQ93231.1 - 0.14 12.2 5.5 0.057 13.4 0.5 2.8 3 0 0 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF2115 PF09888.9 EAQ93231.1 - 0.74 10.3 5.2 1.9 9.0 5.2 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2115) PH_9 PF15410.6 EAQ93231.1 - 1.1 9.7 5.2 0.6 10.5 0.8 2.6 2 1 0 2 2 2 0 Pleckstrin homology domain C2 PF00168.30 EAQ93233.1 - 9.4e-18 64.4 0.0 2.5e-17 63.1 0.0 1.8 1 0 0 1 1 1 1 C2 domain Membr_traf_MHD PF10540.9 EAQ93233.1 - 4e-17 62.7 1.9 6.9e-10 39.3 0.9 3.0 1 1 1 2 2 2 2 Munc13 (mammalian uncoordinated) homology domain DUF810 PF05664.11 EAQ93233.1 - 0.041 12.4 0.0 0.041 12.4 0.0 1.8 2 0 0 2 2 2 0 Plant family of unknown function (DUF810) Pyrophosphatase PF00719.19 EAQ93234.1 - 2.9e-56 189.7 0.1 3.7e-56 189.3 0.1 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase Pro-kuma_activ PF09286.11 EAQ93235.1 - 0.13 12.6 0.1 0.23 11.8 0.1 1.4 1 0 0 1 1 1 0 Pro-kumamolisin, activation domain Pkinase PF00069.25 EAQ93236.1 - 2.3e-25 89.5 0.0 3.3e-25 88.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ93236.1 - 1.9e-13 50.3 0.0 3.6e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RVT_1 PF00078.27 EAQ93236.1 - 2.3e-05 24.0 0.0 3.9e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Herpes_V23 PF01802.17 EAQ93236.1 - 0.16 11.4 0.0 0.25 10.7 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus VP23 like capsid protein ANAPC4_WD40 PF12894.7 EAQ93237.1 - 5.5e-05 23.4 0.0 6.4 7.2 0.1 4.7 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain DUF2583 PF10762.9 EAQ93237.1 - 0.011 16.1 0.8 0.029 14.8 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2583) WD40 PF00400.32 EAQ93237.1 - 0.021 15.7 6.0 12 7.0 0.0 5.0 5 0 0 5 5 5 0 WD domain, G-beta repeat NINJA_B PF16136.5 EAQ93237.1 - 6.9 7.1 10.2 3.3 8.1 2.7 3.1 3 0 0 3 3 3 0 Putative nuclear localisation signal NACHT PF05729.12 EAQ93238.1 - 1.6e-09 37.9 0.1 4.2e-09 36.5 0.1 1.7 1 0 0 1 1 1 1 NACHT domain PNP_UDP_1 PF01048.20 EAQ93238.1 - 2.9e-09 36.5 0.2 1.9e-08 33.9 0.1 2.4 2 1 0 2 2 2 1 Phosphorylase superfamily Ank_2 PF12796.7 EAQ93238.1 - 2.8e-07 31.0 0.0 1.4e-06 28.8 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 EAQ93238.1 - 3.4e-06 27.3 0.1 0.0016 18.8 0.1 3.1 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 EAQ93238.1 - 1.1e-05 25.9 0.1 0.0063 17.1 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) AAA_16 PF13191.6 EAQ93238.1 - 1.1e-05 25.9 2.7 2.3e-05 24.8 0.8 2.3 2 0 0 2 2 2 1 AAA ATPase domain Ank_3 PF13606.6 EAQ93238.1 - 0.00018 21.7 0.0 0.43 11.3 0.0 3.2 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 EAQ93238.1 - 0.0003 21.0 0.0 0.0011 19.3 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) AAA_22 PF13401.6 EAQ93238.1 - 0.00045 20.5 0.0 0.0013 19.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 EAQ93238.1 - 0.0086 15.3 0.0 0.026 13.7 0.0 1.9 1 1 0 1 1 1 1 NB-ARC domain AAA_14 PF13173.6 EAQ93238.1 - 0.023 14.7 0.0 0.77 9.8 0.0 2.8 2 1 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 EAQ93238.1 - 0.058 13.3 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Enkurin PF13864.6 EAQ93238.1 - 0.14 12.6 0.8 0.62 10.5 0.1 2.3 2 0 0 2 2 2 0 Calmodulin-binding PIF1 PF05970.14 EAQ93239.1 - 3.5e-06 26.4 0.0 4.6e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase Indigoidine_A PF04227.12 EAQ93242.1 - 1e-74 251.6 0.0 1.5e-74 251.0 0.0 1.3 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.24 EAQ93242.1 - 1.6e-22 80.2 0.7 8.3e-13 48.3 0.0 2.7 2 1 0 2 2 2 2 pfkB family carbohydrate kinase adh_short PF00106.25 EAQ93243.1 - 2.3e-30 105.5 0.1 3.6e-30 104.9 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EAQ93243.1 - 4.4e-21 75.5 0.1 6.5e-21 74.9 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EAQ93243.1 - 4.2e-05 23.5 0.1 7.3e-05 22.8 0.1 1.3 1 0 0 1 1 1 1 KR domain FAD_binding_3 PF01494.19 EAQ93244.1 - 1.1e-74 251.8 0.0 1.4e-74 251.5 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 EAQ93244.1 - 1.7e-26 93.2 0.0 4.9e-26 91.7 0.0 1.8 2 0 0 2 2 2 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox PF00070.27 EAQ93244.1 - 2.7e-05 24.6 0.1 0.0022 18.5 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EAQ93244.1 - 0.00011 21.6 0.0 0.00061 19.1 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EAQ93244.1 - 0.00042 19.1 0.2 0.00088 18.1 0.2 1.5 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.6 EAQ93244.1 - 0.0011 19.1 0.0 0.003 17.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EAQ93244.1 - 0.0037 16.9 0.0 0.007 16.0 0.0 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EAQ93244.1 - 0.012 14.7 0.3 0.025 13.6 0.2 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 EAQ93244.1 - 0.036 13.4 0.0 0.072 12.4 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 EAQ93244.1 - 0.048 12.9 0.0 0.089 12.0 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EAQ93244.1 - 0.063 12.4 0.3 0.35 9.9 0.2 2.0 2 0 0 2 2 2 0 FAD binding domain 3HCDH_N PF02737.18 EAQ93244.1 - 0.098 12.5 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.22 EAQ93244.1 - 0.1 11.7 0.1 0.15 11.2 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_9 PF13454.6 EAQ93244.1 - 0.12 12.4 0.0 0.28 11.1 0.0 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding Thi4 PF01946.17 EAQ93244.1 - 0.13 11.5 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Thi4 family F-box-like PF12937.7 EAQ93245.1 - 3.5e-06 26.8 1.0 8.1e-06 25.6 1.0 1.6 1 0 0 1 1 1 1 F-box-like HET PF06985.11 EAQ93245.1 - 7.2e-06 26.4 0.6 1.5e-05 25.4 0.0 1.8 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) F-box PF00646.33 EAQ93245.1 - 0.0019 18.0 1.4 0.0041 16.9 1.4 1.5 1 0 0 1 1 1 1 F-box domain Arrestin_N PF00339.29 EAQ93246.1 - 1.3e-16 61.0 0.0 3.7e-16 59.5 0.0 1.8 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 EAQ93246.1 - 6e-05 23.5 0.0 0.0027 18.1 0.0 2.7 2 2 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain NicO PF03824.16 EAQ93247.1 - 0.29 10.5 4.8 0.1 11.9 0.2 2.1 2 0 0 2 2 2 0 High-affinity nickel-transport protein DAP10 PF07213.11 EAQ93247.1 - 0.38 10.7 3.3 0.2 11.7 0.2 2.1 2 0 0 2 2 2 0 DAP10 membrane protein SLD5_C PF16922.5 EAQ93248.1 - 2.5e-12 46.8 0.0 4.1e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus Sld5 PF05916.11 EAQ93248.1 - 8.3e-10 39.1 1.0 3.6e-09 37.0 0.4 2.1 2 0 0 2 2 2 1 GINS complex protein Aldolase_II PF00596.21 EAQ93250.1 - 1.9e-43 148.6 0.0 2.3e-43 148.3 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Calreticulin PF00262.18 EAQ93251.1 - 3.5e-168 559.2 18.6 4.9e-168 558.7 18.6 1.2 1 0 0 1 1 1 1 Calreticulin family DUF1911 PF08929.10 EAQ93251.1 - 0.14 13.0 0.3 0.48 11.3 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1911) YtxH PF12732.7 EAQ93251.1 - 1.7 9.2 7.0 2.2 8.9 3.2 2.6 2 0 0 2 2 2 0 YtxH-like protein Aldedh PF00171.22 EAQ93252.1 - 1.7e-134 448.8 0.1 2e-134 448.6 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family AAA_22 PF13401.6 EAQ93253.1 - 5.8e-13 49.3 0.0 1.5e-12 48.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EAQ93253.1 - 2.6e-12 47.5 1.4 5e-11 43.3 0.1 2.8 2 2 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 EAQ93253.1 - 4.6e-09 36.8 0.0 1e-08 35.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 EAQ93253.1 - 1.2e-06 28.1 0.0 2.4e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Bacterial TniB protein AAA_lid_10 PF17872.1 EAQ93253.1 - 1.1e-05 25.4 0.2 3.6e-05 23.8 0.0 1.9 2 0 0 2 2 2 1 AAA lid domain Cdc6_C PF09079.11 EAQ93253.1 - 1.8e-05 24.6 0.1 9.3e-05 22.3 0.0 2.2 2 0 0 2 2 2 1 CDC6, C terminal winged helix domain NACHT PF05729.12 EAQ93253.1 - 0.00062 19.7 0.1 0.0034 17.3 0.0 2.1 2 0 0 2 2 2 1 NACHT domain AAA_19 PF13245.6 EAQ93253.1 - 0.00076 19.8 0.8 0.0071 16.7 0.0 2.5 2 1 0 2 2 2 1 AAA domain KAP_NTPase PF07693.14 EAQ93253.1 - 0.0044 16.3 0.0 0.0067 15.7 0.0 1.5 1 1 0 1 1 1 1 KAP family P-loop domain T2SSE PF00437.20 EAQ93253.1 - 0.013 14.6 0.4 0.038 13.1 0.0 1.9 3 0 0 3 3 3 0 Type II/IV secretion system protein RNA_helicase PF00910.22 EAQ93253.1 - 0.017 15.5 0.0 0.034 14.5 0.0 1.5 1 0 0 1 1 1 0 RNA helicase MMR_HSR1 PF01926.23 EAQ93253.1 - 0.021 14.9 0.0 0.044 13.9 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_5 PF07728.14 EAQ93253.1 - 0.028 14.4 0.0 0.064 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 EAQ93253.1 - 0.042 13.9 0.0 0.093 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 EAQ93253.1 - 0.046 12.9 0.0 0.086 12.0 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain DUF815 PF05673.13 EAQ93253.1 - 0.055 12.6 0.0 0.11 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 EAQ93253.1 - 0.058 12.9 0.0 0.15 11.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_30 PF13604.6 EAQ93253.1 - 0.084 12.6 0.1 0.24 11.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 EAQ93253.1 - 0.15 12.0 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AIG1 PF04548.16 EAQ93253.1 - 0.22 10.8 2.9 4 6.7 0.7 2.8 2 1 0 2 2 2 0 AIG1 family Aminotran_5 PF00266.19 EAQ93254.1 - 1.1e-29 103.6 0.0 1.6e-29 103.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V MOSC_N PF03476.16 EAQ93254.1 - 1e-22 80.3 0.0 1.9e-22 79.4 0.0 1.5 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.17 EAQ93254.1 - 4.7e-21 75.2 0.0 8.4e-21 74.4 0.0 1.5 1 0 0 1 1 1 1 MOSC domain MBOAT_2 PF13813.6 EAQ93255.1 - 1.3e-11 44.6 0.6 1.3e-11 44.6 0.6 3.7 5 1 0 5 5 5 1 Membrane bound O-acyl transferase family Antimicrobial12 PF08107.11 EAQ93255.1 - 0.084 12.7 0.1 0.16 11.8 0.1 1.4 1 0 0 1 1 1 0 Pleurocidin family Zn_clus PF00172.18 EAQ93256.1 - 5e-08 32.9 11.1 1e-07 32.0 11.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAT1 PF09770.9 EAQ93256.1 - 6.2 5.0 11.1 9.4 4.4 11.1 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 URO-D PF01208.17 EAQ93258.1 - 1.1e-128 429.2 0.0 1.3e-128 429.1 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) PDE8 PF08629.10 EAQ93259.1 - 0.071 13.1 0.2 0.15 12.1 0.2 1.5 1 0 0 1 1 1 0 PDE8 phosphodiesterase DUF3602 PF12223.8 EAQ93260.1 - 5.3e-15 55.8 7.8 4.2e-12 46.5 2.4 2.8 2 2 1 3 3 3 2 Protein of unknown function (DUF3602) Nucleo_P87 PF07267.11 EAQ93261.1 - 4.6 6.0 8.7 5 5.9 8.7 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Transglut_core PF01841.19 EAQ93263.1 - 0.091 13.2 0.4 0.24 11.9 0.4 1.6 1 0 0 1 1 1 0 Transglutaminase-like superfamily Yeast-kill-tox PF09207.11 EAQ93263.1 - 6.7 7.4 8.3 8.4 7.1 0.8 2.9 3 0 0 3 3 3 0 Yeast killer toxin RhoGEF PF00621.20 EAQ93264.1 - 1.7e-30 106.6 0.1 1.7e-30 106.6 0.1 1.8 2 0 0 2 2 2 1 RhoGEF domain BAR PF03114.18 EAQ93264.1 - 1.5e-07 31.3 1.6 4.7e-07 29.7 1.4 1.9 1 1 0 1 1 1 1 BAR domain Telomerase_RBD PF12009.8 EAQ93265.1 - 3.6e-52 176.0 0.8 7.8e-52 174.9 0.8 1.6 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.27 EAQ93265.1 - 0.095 12.2 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Glyco_hydro_7 PF00840.20 EAQ93270.1 - 1.2e-197 656.9 8.8 1.4e-197 656.8 8.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 FolB PF02152.18 EAQ93271.1 - 1.3e-20 74.0 0.0 4.2e-16 59.5 0.0 2.4 2 0 0 2 2 2 2 Dihydroneopterin aldolase UDPGP PF01704.18 EAQ93273.1 - 6e-191 634.5 0.0 6.9e-191 634.3 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase PilO PF04350.13 EAQ93273.1 - 0.13 12.4 0.0 0.37 10.9 0.0 1.7 1 0 0 1 1 1 0 Pilus assembly protein, PilO ING PF12998.7 EAQ93274.1 - 4e-23 81.9 6.7 5.8e-23 81.4 6.7 1.3 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 EAQ93274.1 - 0.00037 20.3 9.7 0.00062 19.6 9.7 1.3 1 0 0 1 1 1 1 PHD-finger NusB PF01029.18 EAQ93274.1 - 0.72 10.1 4.4 1 9.6 1.1 2.1 1 1 1 2 2 2 0 NusB family Tmemb_cc2 PF10267.9 EAQ93274.1 - 2 7.5 7.2 3.6 6.6 7.1 1.6 1 1 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein DUF2880 PF11082.8 EAQ93274.1 - 2.4 8.5 7.4 13 6.2 1.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2880) PP1_bind PF15276.6 EAQ93274.1 - 3.9 7.9 7.2 0.34 11.2 0.6 2.7 3 0 0 3 3 3 0 Protein phosphatase 1 binding Hist_deacetyl PF00850.19 EAQ93275.1 - 6.5e-81 272.2 0.0 8.3e-81 271.8 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain MFS_1 PF07690.16 EAQ93276.1 - 9.1e-09 34.7 24.3 9.1e-09 34.7 24.3 3.0 2 1 0 3 3 3 1 Major Facilitator Superfamily DUF1270 PF06900.11 EAQ93276.1 - 0.079 13.3 1.4 5.7 7.4 0.2 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1270) MCLC PF05934.11 EAQ93276.1 - 0.15 10.8 0.8 0.35 9.6 0.1 1.8 2 0 0 2 2 2 0 Mid-1-related chloride channel (MCLC) WW PF00397.26 EAQ93277.1 - 1.3e-11 44.3 0.1 4.2e-11 42.7 0.1 2.0 1 0 0 1 1 1 1 WW domain PhoD PF09423.10 EAQ93277.1 - 0.095 11.7 0.3 0.89 8.5 0.1 2.1 2 0 0 2 2 2 0 PhoD-like phosphatase PMM PF03332.13 EAQ93278.1 - 6.4e-104 346.5 0.4 7.5e-104 346.3 0.4 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 EAQ93278.1 - 0.00073 19.4 0.0 0.0052 16.5 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EAQ93278.1 - 0.0097 16.3 0.0 3.8 7.9 0.0 2.7 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase S6PP PF05116.13 EAQ93278.1 - 0.016 14.8 0.0 1.1 8.8 0.0 2.1 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase Na_Ca_ex PF01699.24 EAQ93279.1 - 7e-21 74.8 5.9 7e-21 74.8 5.9 1.6 1 1 1 2 2 2 1 Sodium/calcium exchanger protein Na_Ca_ex PF01699.24 EAQ93280.1 - 1.3e-27 96.7 20.3 1.6e-27 96.3 19.1 1.7 2 0 0 2 2 2 1 Sodium/calcium exchanger protein Cnd2 PF05786.14 EAQ93281.1 - 0 1028.3 0.9 0 1028.1 0.9 1.0 1 0 0 1 1 1 1 Condensin complex subunit 2 CNDH2_N PF06278.11 EAQ93281.1 - 0.0026 17.9 0.0 0.011 15.9 0.0 2.1 1 0 0 1 1 1 1 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal HMG_box PF00505.19 EAQ93284.1 - 5.6e-10 39.5 2.1 9.3e-10 38.8 0.3 2.0 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EAQ93284.1 - 3.7e-07 30.6 0.2 3.7e-07 30.6 0.2 1.7 2 0 0 2 2 2 1 HMG-box domain WYL_3 PF18488.1 EAQ93284.1 - 0.021 15.2 1.4 0.042 14.2 1.4 1.4 1 0 0 1 1 1 0 WYL domain MlaC PF05494.12 EAQ93284.1 - 0.057 13.2 0.2 0.087 12.6 0.2 1.3 1 0 0 1 1 1 0 MlaC protein DUF4717 PF15838.5 EAQ93284.1 - 0.096 12.7 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4717) SOG2 PF10428.9 EAQ93284.1 - 0.11 11.6 13.1 0.12 11.5 13.1 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein PAP1 PF08601.10 EAQ93284.1 - 0.63 9.7 14.5 0.71 9.5 14.5 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 HATPase_c PF02518.26 EAQ93286.1 - 3.7e-31 107.9 0.1 1.1e-30 106.3 0.1 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HAMP PF00672.25 EAQ93286.1 - 7.9e-31 106.2 14.1 1.1e-07 32.2 0.1 6.6 6 1 0 6 6 5 4 HAMP domain Response_reg PF00072.24 EAQ93286.1 - 9.4e-26 90.2 0.4 9.4e-26 90.2 0.4 2.9 3 0 0 3 3 3 1 Response regulator receiver domain HisKA PF00512.25 EAQ93286.1 - 2e-17 62.9 2.4 7.5e-17 61.1 0.5 3.0 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain Syntaxin_2 PF14523.6 EAQ93286.1 - 4.3e-05 23.8 11.1 3.9 7.9 0.0 6.3 2 2 4 7 7 7 3 Syntaxin-like protein Fib_alpha PF08702.10 EAQ93286.1 - 0.0017 18.5 27.0 0.18 12.0 0.2 5.5 5 0 0 5 5 5 2 Fibrinogen alpha/beta chain family DUF948 PF06103.11 EAQ93286.1 - 0.0017 18.5 34.9 0.22 11.8 0.4 8.1 6 2 1 7 7 6 2 Bacterial protein of unknown function (DUF948) DUF4279 PF14106.6 EAQ93286.1 - 0.042 14.1 0.0 15 5.8 0.0 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4279) DUF883 PF05957.13 EAQ93286.1 - 0.12 12.9 8.2 5.4 7.7 0.1 4.2 3 1 0 4 4 3 0 Bacterial protein of unknown function (DUF883) GLE1 PF07817.13 EAQ93286.1 - 0.18 11.0 1.3 2.6 7.2 0.1 3.0 3 0 0 3 3 3 0 GLE1-like protein GhoS PF11080.8 EAQ93286.1 - 0.45 10.5 2.0 1.3 9.1 0.1 2.8 3 0 0 3 3 3 0 Endoribonuclease GhoS GatB_Yqey PF02637.18 EAQ93286.1 - 0.57 10.0 6.3 1.7 8.5 0.0 3.9 4 0 0 4 4 4 0 GatB domain AdHead_fibreRBD PF16812.5 EAQ93286.1 - 1.3 8.9 3.6 1.4 8.7 0.2 2.8 3 0 0 3 3 3 0 C-terminal head domain of the fowl adenovirus type 1 long fibre BORCS6 PF10157.9 EAQ93286.1 - 6.1 7.0 8.0 14 5.9 0.0 4.5 4 2 0 5 5 5 0 BLOC-1-related complex sub-unit 6 DUF3829 PF12889.7 EAQ93286.1 - 7.5 5.9 9.2 1.2 8.6 0.1 3.7 4 1 1 5 5 5 0 Protein of unknown function (DUF3829) WXG100 PF06013.12 EAQ93286.1 - 8.9 6.6 18.6 3.2 8.1 0.2 6.8 3 3 3 7 7 7 0 Proteins of 100 residues with WXG Dus PF01207.17 EAQ93288.1 - 1.8e-40 139.0 0.1 5.7e-40 137.3 0.1 1.8 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) TRP PF06011.12 EAQ93289.1 - 1.3e-147 491.9 16.0 1.7e-147 491.6 16.0 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 EAQ93289.1 - 4.6e-40 137.2 3.2 7.5e-40 136.5 3.2 1.4 1 0 0 1 1 1 1 ML-like domain DUF2663 PF10864.8 EAQ93289.1 - 0.9 9.9 5.1 1.2 9.6 0.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2663) Shisa PF13908.6 EAQ93289.1 - 4.3 7.5 5.6 19 5.4 0.4 2.6 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Tmemb_14 PF03647.13 EAQ93292.1 - 2.5e-23 82.6 6.4 2.9e-23 82.4 6.4 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C Aim19 PF10315.9 EAQ93292.1 - 0.063 13.6 0.6 0.53 10.6 0.6 2.1 1 1 0 1 1 1 0 Altered inheritance of mitochondria protein 19 CytB6-F_Fe-S PF08802.10 EAQ93292.1 - 0.71 10.0 7.4 1.7 8.8 0.1 2.9 3 0 0 3 3 3 0 Cytochrome B6-F complex Fe-S subunit Prefoldin_2 PF01920.20 EAQ93293.1 - 3e-25 88.2 4.1 3.5e-25 88.0 4.1 1.0 1 0 0 1 1 1 1 Prefoldin subunit DUF4757 PF15949.5 EAQ93293.1 - 0.0092 16.5 0.1 0.011 16.2 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4757) DUF2089 PF09862.9 EAQ93293.1 - 0.01 15.8 0.6 0.086 12.9 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2089) DUF2205 PF10224.9 EAQ93293.1 - 0.021 14.8 0.9 0.76 9.8 0.0 2.1 2 0 0 2 2 2 0 Short coiled-coil protein DUF2956 PF11169.8 EAQ93293.1 - 0.04 14.1 0.3 0.04 14.1 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) Prefoldin PF02996.17 EAQ93293.1 - 0.18 11.7 3.6 1.9 8.4 0.3 2.1 1 1 0 2 2 2 0 Prefoldin subunit CBFD_NFYB_HMF PF00808.23 EAQ93294.1 - 2e-29 101.7 1.2 2.6e-29 101.3 1.2 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EAQ93294.1 - 3.6e-06 27.4 0.2 6.2e-06 26.6 0.0 1.5 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.16 EAQ93294.1 - 0.001 19.1 0.0 0.0014 18.6 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.13 EAQ93294.1 - 0.001 19.0 0.0 0.002 18.1 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated CENP-T_C PF15511.6 EAQ93294.1 - 0.0024 18.0 0.0 0.0031 17.6 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TFIID_20kDa PF03847.13 EAQ93294.1 - 0.042 14.4 0.0 0.071 13.6 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A GMC_oxred_N PF00732.19 EAQ93295.1 - 1.3e-47 162.6 0.0 1.7e-47 162.3 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EAQ93295.1 - 8.1e-42 143.2 0.0 1.6e-41 142.2 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 EAQ93295.1 - 1.8e-05 24.5 0.2 9.6e-05 22.1 0.1 2.2 2 1 1 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EAQ93295.1 - 2e-05 23.9 7.6 0.0037 16.4 6.1 2.5 2 1 1 3 3 3 2 FAD binding domain Pyr_redox_3 PF13738.6 EAQ93295.1 - 0.00068 19.0 0.7 0.11 11.7 0.6 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EAQ93295.1 - 0.0012 19.1 0.2 0.0033 17.6 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EAQ93295.1 - 0.0032 16.7 0.7 0.011 15.0 0.6 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EAQ93295.1 - 0.007 15.5 0.4 0.011 14.8 0.4 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Trp_halogenase PF04820.14 EAQ93295.1 - 0.0097 14.8 0.7 0.013 14.3 0.7 1.1 1 0 0 1 1 1 1 Tryptophan halogenase Soyouz_module PF14313.6 EAQ93295.1 - 0.03 14.1 0.1 1.2 9.0 0.1 2.5 2 0 0 2 2 2 0 N-terminal region of Paramyxovirinae phosphoprotein (P) Thi4 PF01946.17 EAQ93295.1 - 0.051 12.8 0.4 0.1 11.9 0.4 1.4 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.22 EAQ93295.1 - 0.11 11.6 1.2 0.17 10.9 1.2 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A HI0933_like PF03486.14 EAQ93295.1 - 0.47 9.1 1.1 0.66 8.6 1.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Fungal_trans PF04082.18 EAQ93296.1 - 4.3e-20 71.9 0.0 6.2e-20 71.3 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EAQ93296.1 - 1e-06 28.8 10.4 1.8e-06 27.9 10.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pox_A_type_inc PF04508.12 EAQ93296.1 - 0.082 12.8 0.6 0.16 11.9 0.6 1.5 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat MFS_1 PF07690.16 EAQ93297.1 - 5.3e-11 42.0 28.3 1.3e-10 40.7 28.2 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily RuvA_C PF07499.13 EAQ93297.1 - 0.17 12.4 2.2 9 6.8 0.0 2.7 2 1 0 2 2 2 0 RuvA, C-terminal domain ADH_N PF08240.12 EAQ93299.1 - 3.8e-26 91.1 3.7 7.5e-26 90.2 3.7 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EAQ93299.1 - 1.4e-15 57.4 0.1 2.3e-15 56.7 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EAQ93299.1 - 0.0011 20.0 0.0 0.0032 18.5 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ELFV_dehydrog PF00208.21 EAQ93299.1 - 0.0015 18.3 0.1 0.0026 17.5 0.1 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 2-Hacid_dh_C PF02826.19 EAQ93299.1 - 0.005 16.2 0.1 0.011 15.2 0.1 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Glu_dehyd_C PF16912.5 EAQ93299.1 - 0.0094 15.5 0.3 0.017 14.6 0.3 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus Haem_degrading PF03928.14 EAQ93299.1 - 0.095 12.8 1.0 0.35 10.9 0.3 2.1 2 0 0 2 2 2 0 Haem-degrading DUF1450 PF07293.11 EAQ93299.1 - 1.8 8.4 3.7 24 4.8 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1450) Sortilin-Vps10 PF15902.5 EAQ93300.1 - 0.011 14.5 1.2 0.67 8.7 0.1 2.7 3 0 0 3 3 3 0 Sortilin, neurotensin receptor 3, BNR PF02012.20 EAQ93300.1 - 0.16 12.1 9.2 4.1 7.8 0.2 4.0 3 0 0 3 3 3 0 BNR/Asp-box repeat RRN3 PF05327.11 EAQ93301.1 - 3.1e-155 517.9 0.0 3.1e-155 517.9 0.0 1.5 2 0 0 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 bZIP_1 PF00170.21 EAQ93301.1 - 0.006 16.7 8.1 0.015 15.3 8.1 1.7 1 0 0 1 1 1 1 bZIP transcription factor DUF4407 PF14362.6 EAQ93301.1 - 0.38 10.1 5.1 0.86 8.9 5.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) eIF-3_zeta PF05091.12 EAQ93301.1 - 2.7 6.9 5.7 0.3 10.0 0.4 1.8 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF2205 PF10224.9 EAQ93301.1 - 5.6 7.0 7.6 12 6.0 3.2 2.8 2 0 0 2 2 2 0 Short coiled-coil protein WSC PF01822.19 EAQ93303.1 - 7.3e-75 247.2 69.3 6.8e-20 71.1 11.6 5.3 4 1 1 5 5 5 5 WSC domain Glyoxal_oxid_N PF07250.11 EAQ93303.1 - 6.8e-26 90.9 0.0 1.3e-25 90.1 0.0 1.4 1 0 0 1 1 1 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 EAQ93303.1 - 9.3e-20 70.7 0.0 1.9e-19 69.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Ank_2 PF12796.7 EAQ93305.1 - 1.1e-32 112.5 10.2 4.1e-16 59.3 1.4 3.9 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 EAQ93305.1 - 1.3e-31 107.6 24.0 0.00051 20.4 0.1 8.2 8 0 0 8 8 8 7 Ankyrin repeat Ank_4 PF13637.6 EAQ93305.1 - 7.8e-27 93.3 7.3 1.1e-07 32.3 0.1 7.1 2 1 6 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAQ93305.1 - 3.6e-24 82.2 4.3 0.0012 19.2 0.1 7.9 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 EAQ93305.1 - 1.6e-23 82.4 11.0 1e-07 32.0 0.1 6.3 3 2 3 6 6 6 4 Ankyrin repeats (many copies) ABC_tran PF00005.27 EAQ93305.1 - 0.029 14.9 0.0 0.069 13.7 0.0 1.7 1 0 0 1 1 1 0 ABC transporter DUF3789 PF12664.7 EAQ93305.1 - 0.22 11.3 0.7 0.48 10.2 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3789) Oxysterol_BP PF01237.18 EAQ93306.1 - 2.7e-38 131.8 0.1 5.6e-32 111.0 0.0 2.0 2 0 0 2 2 2 2 Oxysterol-binding protein SQHop_cyclase_C PF13243.6 EAQ93307.1 - 5.7e-52 176.8 0.0 2.3e-48 165.0 0.1 2.1 2 0 0 2 2 2 2 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 EAQ93307.1 - 3.3e-42 144.6 0.5 7.8e-34 117.1 0.0 4.6 4 1 2 6 6 6 3 Squalene-hopene cyclase N-terminal domain Prenyltrans PF00432.21 EAQ93307.1 - 9e-33 111.7 6.9 1e-09 37.9 0.0 5.9 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat TED_complement PF07678.14 EAQ93307.1 - 0.0023 17.0 0.0 0.031 13.3 0.0 2.5 2 1 1 3 3 3 1 A-macroglobulin TED domain Pec_lyase PF09492.10 EAQ93307.1 - 0.013 14.8 0.0 0.78 9.0 0.0 3.0 2 1 1 3 3 3 0 Pectic acid lyase Nas2_N PF18265.1 EAQ93309.1 - 1.8e-28 98.2 0.0 2.6e-28 97.8 0.0 1.2 1 0 0 1 1 1 1 Nas2 N_terminal domain PDZ_6 PF17820.1 EAQ93309.1 - 1.4e-08 34.4 0.1 2.8e-08 33.5 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EAQ93309.1 - 3.4e-07 30.5 0.0 5.9e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.14 EAQ93309.1 - 9.4e-06 26.0 0.0 1.8e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain PDZ PF00595.24 EAQ93309.1 - 4.1e-05 23.8 0.0 6.6e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 PDZ domain RhoGEF PF00621.20 EAQ93310.1 - 0.029 14.6 0.0 0.048 13.9 0.0 1.3 1 0 0 1 1 1 0 RhoGEF domain SBDS PF01172.18 EAQ93311.1 - 1.5e-20 73.1 0.0 1.8e-20 72.8 0.0 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein MgtE PF01769.16 EAQ93312.1 - 0.31 11.4 2.5 0.3 11.5 0.3 1.8 2 0 0 2 2 2 0 Divalent cation transporter OPA3 PF07047.12 EAQ93314.1 - 6.4e-30 103.5 0.8 1e-29 102.9 0.8 1.3 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) DUF2681 PF10883.8 EAQ93314.1 - 0.0026 18.1 0.2 0.0026 18.1 0.2 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2681) VSG_B PF13206.6 EAQ93314.1 - 0.086 12.1 4.3 0.11 11.7 4.3 1.1 1 0 0 1 1 1 0 Trypanosomal VSG domain PAP_PilO PF06864.12 EAQ93314.1 - 0.1 11.4 1.5 0.25 10.1 1.5 1.7 1 1 0 1 1 1 0 Pilin accessory protein (PilO) CAF-1_p150 PF11600.8 EAQ93314.1 - 0.15 11.7 21.5 0.55 9.9 6.9 2.1 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal HAUS6_N PF14661.6 EAQ93314.1 - 0.16 11.5 9.5 1.5 8.3 1.0 2.0 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus Bac_luciferase PF00296.20 EAQ93314.1 - 0.2 11.1 6.5 1.3 8.4 6.5 1.9 1 1 0 1 1 1 0 Luciferase-like monooxygenase Tho2 PF11262.8 EAQ93314.1 - 0.23 10.6 9.5 0.57 9.3 1.5 2.0 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 DUF16 PF01519.16 EAQ93314.1 - 0.47 11.0 6.1 1.2 9.7 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF16 PIEZO PF15917.5 EAQ93314.1 - 4.1 6.8 8.0 1 8.8 0.7 2.0 2 0 0 2 2 2 0 Piezo Pkinase PF00069.25 EAQ93315.1 - 5.5e-67 225.9 0.0 8.1e-67 225.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ93315.1 - 8.4e-41 140.0 0.0 1.2e-40 139.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAQ93315.1 - 1.2e-07 31.3 0.0 3.2e-07 30.0 0.0 1.6 1 1 0 1 1 1 1 Kinase-like POLO_box PF00659.18 EAQ93315.1 - 2.6e-06 27.5 0.1 0.0039 17.4 0.0 2.8 2 0 0 2 2 2 2 POLO box duplicated region Kdo PF06293.14 EAQ93315.1 - 0.00043 19.7 0.0 0.00079 18.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EAQ93315.1 - 0.021 13.8 0.1 0.049 12.6 0.1 1.5 2 0 0 2 2 2 0 Haspin like kinase domain Pkinase_fungal PF17667.1 EAQ93315.1 - 0.039 12.7 3.6 0.042 12.6 0.0 2.2 2 1 0 2 2 2 0 Fungal protein kinase Sushi_2 PF09014.10 EAQ93315.1 - 0.11 12.3 0.1 0.27 11.1 0.1 1.6 1 0 0 1 1 1 0 Beta-2-glycoprotein-1 fifth domain SRP-alpha_N PF04086.13 EAQ93315.1 - 1.2 9.0 8.1 2.8 7.8 8.1 1.6 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal FAD_binding_3 PF01494.19 EAQ93316.1 - 7.9e-13 48.4 0.0 1.1e-12 47.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain BLOC1_2 PF10046.9 EAQ93317.1 - 0.0032 17.7 4.7 0.0032 17.7 4.7 2.4 2 1 0 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1664 PF07889.12 EAQ93317.1 - 0.02 14.9 0.5 0.02 14.9 0.5 2.4 3 0 0 3 3 2 0 Protein of unknown function (DUF1664) TMF_DNA_bd PF12329.8 EAQ93317.1 - 0.025 14.6 5.8 0.025 14.6 5.8 2.8 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding WXG100 PF06013.12 EAQ93317.1 - 0.083 13.1 4.5 6.2 7.1 0.3 2.9 2 1 0 2 2 2 0 Proteins of 100 residues with WXG Sec8_exocyst PF04048.14 EAQ93317.1 - 0.094 12.6 5.0 1.3 8.9 1.2 2.1 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain DUF3450 PF11932.8 EAQ93317.1 - 0.11 11.8 20.5 0.76 9.0 9.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DUF16 PF01519.16 EAQ93317.1 - 0.35 11.4 13.3 0.69 10.4 6.8 2.3 2 0 0 2 2 2 0 Protein of unknown function DUF16 BST2 PF16716.5 EAQ93317.1 - 0.38 11.4 17.3 0.098 13.3 5.9 2.9 2 1 1 3 3 3 0 Bone marrow stromal antigen 2 GldM_N PF12081.8 EAQ93317.1 - 0.46 10.6 6.9 0.16 12.0 0.8 2.2 2 0 0 2 2 2 0 GldM N-terminal domain FlaC_arch PF05377.11 EAQ93317.1 - 0.53 10.7 3.0 0.45 10.9 0.5 2.1 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) M_domain PF12938.7 EAQ93317.1 - 1.1 9.0 3.5 1 9.1 0.1 2.1 2 0 0 2 2 2 0 M domain of GW182 DivIC PF04977.15 EAQ93317.1 - 1.2 9.0 14.8 0.13 12.0 6.5 2.9 2 1 0 2 2 2 0 Septum formation initiator T3SSipB PF16535.5 EAQ93317.1 - 1.2 9.6 11.4 0.18 12.3 2.3 2.4 2 0 0 2 2 2 0 Type III cell invasion protein SipB DUF1706 PF08020.11 EAQ93317.1 - 1.2 9.0 8.0 0.44 10.5 0.3 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1706) Tropomyosin PF00261.20 EAQ93317.1 - 1.2 8.4 29.6 0.82 9.0 26.0 2.3 1 1 1 2 2 2 0 Tropomyosin Prefoldin PF02996.17 EAQ93317.1 - 1.5 8.8 14.3 0.19 11.6 3.8 3.3 2 2 2 4 4 4 0 Prefoldin subunit TBCC_N PF16752.5 EAQ93317.1 - 1.6 9.2 13.7 1.1 9.7 4.8 2.5 2 0 0 2 2 2 0 Tubulin-specific chaperone C N-terminal domain Rx_N PF18052.1 EAQ93317.1 - 2.3 8.6 11.5 0.083 13.2 2.4 2.5 2 1 1 3 3 3 0 Rx N-terminal domain FH2 PF02181.23 EAQ93317.1 - 2.6 7.1 12.9 0.22 10.6 3.6 2.1 2 0 0 2 2 2 0 Formin Homology 2 Domain APG6_N PF17675.1 EAQ93317.1 - 2.7 8.5 31.7 5 7.6 17.4 2.2 2 0 0 2 2 2 0 Apg6 coiled-coil region Snapin_Pallidin PF14712.6 EAQ93317.1 - 3 8.3 12.6 3.2 8.2 2.0 2.2 2 0 0 2 2 2 0 Snapin/Pallidin DUF5344 PF17279.2 EAQ93317.1 - 3.1 8.4 8.1 11 6.7 3.6 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5344) Acetyltransf_11 PF13720.6 EAQ93317.1 - 3.4 8.2 7.2 1.2 9.6 2.7 2.3 2 0 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Swi5 PF07061.11 EAQ93317.1 - 4.5 7.4 13.8 2.9 8.0 4.4 3.3 2 1 1 3 3 3 0 Swi5 DUF641 PF04859.12 EAQ93317.1 - 4.7 7.6 22.6 0.89 9.9 8.6 2.2 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) Phage_GP20 PF06810.11 EAQ93317.1 - 5.2 6.9 13.7 0.3 10.9 5.3 2.2 2 0 0 2 2 2 0 Phage minor structural protein GP20 zf-CpG_bind_C PF12269.8 EAQ93317.1 - 5.6 6.7 11.3 1.7 8.4 3.1 2.2 2 0 0 2 2 2 0 CpG binding protein zinc finger C terminal domain DUF1657 PF07870.11 EAQ93317.1 - 5.7 6.9 9.7 9.3 6.2 5.2 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1657) Fib_alpha PF08702.10 EAQ93317.1 - 8.1 6.6 13.3 2.3 8.4 5.7 2.7 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Abhydrolase_1 PF00561.20 EAQ93318.1 - 4.4e-13 49.5 0.0 6e-13 49.0 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EAQ93318.1 - 3.2e-08 34.4 0.0 3.8e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EAQ93318.1 - 0.0016 17.7 0.0 0.0024 17.2 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S28 PF05577.12 EAQ93318.1 - 0.0021 17.0 0.0 0.0028 16.5 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Ribonuc_2-5A PF06479.12 EAQ93318.1 - 0.12 12.5 0.0 0.72 10.0 0.0 2.1 2 0 0 2 2 2 0 Ribonuclease 2-5A WD40 PF00400.32 EAQ93319.1 - 2e-18 66.4 9.8 0.00046 20.9 0.0 6.9 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAQ93319.1 - 4.3e-07 30.1 0.0 0.016 15.5 0.0 4.1 4 2 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 EAQ93319.1 - 0.017 15.0 0.1 3.1 7.8 0.1 2.9 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat RRM_1 PF00076.22 EAQ93320.1 - 2.1e-08 33.8 0.0 5.9e-08 32.4 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EAQ93320.1 - 1.4e-06 27.9 0.0 2.1e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 EAQ93320.1 - 0.0077 16.3 0.0 0.016 15.3 0.0 1.4 1 0 0 1 1 1 1 Limkain b1 Calcipressin PF04847.12 EAQ93320.1 - 0.014 15.2 0.1 0.043 13.6 0.1 1.8 1 1 1 2 2 2 0 Calcipressin RRM_occluded PF16842.5 EAQ93320.1 - 0.15 11.9 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 Occluded RNA-recognition motif Glyco_hydro_47 PF01532.20 EAQ93322.1 - 1.1e-161 538.8 0.0 1.5e-161 538.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF4038 PF13204.6 EAQ93322.1 - 0.029 14.0 0.1 0.062 12.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4038) DUF883 PF05957.13 EAQ93322.1 - 0.087 13.4 0.2 0.22 12.1 0.2 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) AA_permease PF00324.21 EAQ93323.1 - 3.9e-142 474.2 32.1 8.2e-140 466.6 27.7 2.0 2 0 0 2 2 2 2 Amino acid permease AA_permease_2 PF13520.6 EAQ93323.1 - 1.1e-36 126.7 30.4 1.4e-36 126.3 30.4 1.1 1 0 0 1 1 1 1 Amino acid permease Glyco_transf_25 PF01755.17 EAQ93327.1 - 0.14 12.0 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 25 (LPS biosynthesis protein) DUF4131 PF13567.6 EAQ93327.1 - 2.1 8.0 7.3 8.3 6.0 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) MFS_1 PF07690.16 EAQ93328.1 - 1.3e-05 24.3 8.0 2.8e-05 23.2 7.6 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EAQ93328.1 - 0.12 10.9 5.8 0.24 9.9 5.8 1.4 1 1 0 1 1 1 0 MFS/sugar transport protein F-box-like PF12937.7 EAQ93329.1 - 8.2e-06 25.6 0.5 1.7e-05 24.6 0.5 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EAQ93329.1 - 0.00012 21.9 2.1 0.00047 20.0 2.1 2.0 1 1 0 1 1 1 1 F-box domain AMP-binding PF00501.28 EAQ93330.1 - 4.6e-97 325.3 0.0 6e-97 324.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EAQ93330.1 - 7.5e-18 65.3 0.9 1.8e-17 64.0 0.9 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ATP11 PF06644.11 EAQ93331.1 - 4.8e-99 331.6 0.0 5.6e-99 331.3 0.0 1.0 1 0 0 1 1 1 1 ATP11 protein Totivirus_coat PF05518.11 EAQ93331.1 - 0.47 8.4 3.7 0.6 8.1 3.7 1.1 1 0 0 1 1 1 0 Totivirus coat protein peroxidase PF00141.23 EAQ93332.1 - 1.5e-47 162.3 0.0 2.2e-47 161.7 0.0 1.2 1 0 0 1 1 1 1 Peroxidase EcoR124_C PF12008.8 EAQ93332.1 - 0.068 12.8 0.0 1.3 8.6 0.0 2.2 2 0 0 2 2 2 0 Type I restriction and modification enzyme - subunit R C terminal DUF4810 PF16068.5 EAQ93333.1 - 0.02 15.4 0.3 1 9.9 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4810) TPR_14 PF13428.6 EAQ93333.1 - 3.2 8.8 8.6 65 4.7 0.0 5.2 5 1 1 6 6 6 0 Tetratricopeptide repeat Syja_N PF02383.18 EAQ93334.1 - 9.9e-72 241.9 0.0 1.4e-71 241.4 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.23 EAQ93334.1 - 3.3e-08 33.3 0.0 7.1e-08 32.2 0.0 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SPACA7 PF15307.6 EAQ93334.1 - 0.18 12.1 0.0 0.4 11.0 0.0 1.5 1 0 0 1 1 1 0 Sperm acrosome-associated protein 7 14-3-3 PF00244.20 EAQ93336.1 - 2.4e-107 357.5 1.0 2.8e-107 357.3 1.0 1.0 1 0 0 1 1 1 1 14-3-3 protein Lipase_3 PF01764.25 EAQ93337.1 - 0.043 13.7 0.0 11 5.9 0.0 2.2 2 0 0 2 2 2 0 Lipase (class 3) SOG2 PF10428.9 EAQ93337.1 - 0.49 9.5 2.1 0.62 9.2 2.1 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein 2-ph_phosp PF04029.14 EAQ93339.1 - 0.073 12.2 0.0 0.093 11.9 0.0 1.1 1 0 0 1 1 1 0 2-phosphosulpholactate phosphatase TUG-UBL1 PF11470.8 EAQ93340.1 - 9.2e-25 86.6 0.0 3.2e-24 84.9 0.0 2.0 2 0 0 2 2 2 1 TUG ubiquitin-like domain UBX PF00789.20 EAQ93340.1 - 0.0012 19.0 0.0 0.0065 16.6 0.0 2.2 3 0 0 3 3 3 1 UBX domain RBD PF02196.15 EAQ93340.1 - 0.016 15.2 0.0 0.1 12.7 0.0 2.2 2 0 0 2 2 2 0 Raf-like Ras-binding domain Proteasome PF00227.26 EAQ93341.1 - 2.3e-38 131.6 0.0 2.6e-38 131.4 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit E1-E2_ATPase PF00122.20 EAQ93342.1 - 5.4e-51 172.7 4.1 3.1e-50 170.2 1.8 2.8 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 EAQ93342.1 - 6.6e-46 156.3 4.9 6.6e-46 156.3 4.9 1.7 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EAQ93342.1 - 7e-23 82.0 1.8 1e-21 78.2 1.8 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EAQ93342.1 - 4.2e-21 74.8 0.0 8.2e-21 73.9 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 EAQ93342.1 - 3.4e-18 65.1 0.8 6.9e-18 64.1 0.1 2.0 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EAQ93342.1 - 2.2e-09 37.5 0.8 4.7e-06 26.5 1.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 EAQ93342.1 - 3.4e-06 27.6 0.0 1.3e-05 25.7 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase TBCA PF02970.16 EAQ93343.1 - 2.1e-25 88.8 14.2 3.2e-25 88.3 9.2 2.0 1 1 1 2 2 2 1 Tubulin binding cofactor A Csm1_N PF18504.1 EAQ93343.1 - 0.036 14.4 10.7 0.049 14.0 3.5 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain Exonuc_VII_L PF02601.15 EAQ93343.1 - 0.096 12.2 3.1 0.11 12.0 3.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Spc7 PF08317.11 EAQ93343.1 - 0.19 10.6 9.6 0.13 11.1 7.9 1.3 1 1 0 1 1 1 0 Spc7 kinetochore protein Tropomyosin PF00261.20 EAQ93343.1 - 0.25 10.7 17.6 4.2 6.7 17.6 2.0 1 1 0 1 1 1 0 Tropomyosin DUF4404 PF14357.6 EAQ93343.1 - 0.3 11.7 7.4 2.8 8.6 0.5 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) TMPIT PF07851.13 EAQ93343.1 - 1 8.5 6.9 0.35 10.1 3.9 1.6 1 1 1 2 2 2 0 TMPIT-like protein DUF1910 PF08928.10 EAQ93343.1 - 1.1 9.3 6.7 2.8 7.9 6.7 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF1910) TMF_DNA_bd PF12329.8 EAQ93343.1 - 3.9 7.5 16.4 6.3 6.9 6.4 2.3 1 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF4407 PF14362.6 EAQ93343.1 - 6.2 6.1 8.3 7.8 5.8 8.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) XhlA PF10779.9 EAQ93343.1 - 8.5 6.7 7.4 22 5.4 1.2 2.5 1 1 1 2 2 2 0 Haemolysin XhlA THOC7 PF05615.13 EAQ93344.1 - 7.5e-46 155.7 8.7 7.5e-46 155.7 8.7 2.2 2 0 0 2 2 2 1 Tho complex subunit 7 Sigma70_ner PF04546.13 EAQ93344.1 - 0.29 11.0 15.5 0.048 13.5 4.0 2.8 3 1 0 3 3 3 0 Sigma-70, non-essential region RTBV_P46 PF06216.11 EAQ93344.1 - 0.4 9.5 1.1 0.56 9.0 0.6 1.4 1 1 0 1 1 1 0 Rice tungro bacilliform virus P46 protein PilO PF04350.13 EAQ93344.1 - 0.56 10.4 4.3 2.9 8.0 0.5 2.7 1 1 1 2 2 2 0 Pilus assembly protein, PilO DUF4407 PF14362.6 EAQ93344.1 - 9 5.5 16.4 14 4.9 16.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Elongin_A PF06881.11 EAQ93345.1 - 7.9e-27 93.8 1.5 1.3e-26 93.2 1.5 1.3 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A ubiquitin PF00240.23 EAQ93346.1 - 1.3e-22 79.3 0.1 1.6e-22 79.1 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EAQ93346.1 - 1.1e-09 38.0 0.1 1.3e-09 37.8 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 EAQ93346.1 - 0.059 13.3 0.0 0.079 12.9 0.0 1.2 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_2 PF14560.6 EAQ93346.1 - 0.12 12.8 0.0 0.17 12.3 0.0 1.3 1 1 0 1 1 1 0 Ubiquitin-like domain Band_7 PF01145.25 EAQ93347.1 - 1.2e-23 84.0 2.6 1.8e-23 83.5 2.6 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family CSTF2_hinge PF14327.6 EAQ93348.1 - 1.9e-33 114.8 1.6 1.9e-33 114.8 1.6 1.9 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.22 EAQ93348.1 - 1.1e-22 79.6 0.0 1.7e-22 79.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.6 EAQ93348.1 - 2.2e-10 39.9 3.4 2.2e-10 39.9 3.4 2.9 4 0 0 4 4 4 1 Transcription termination and cleavage factor C-terminal RRM_7 PF16367.5 EAQ93348.1 - 0.062 13.4 0.0 0.1 12.7 0.0 1.5 1 1 0 1 1 1 0 RNA recognition motif L1R_F9L PF02442.17 EAQ93348.1 - 0.17 11.7 0.3 0.39 10.5 0.1 1.7 2 0 0 2 2 2 0 Lipid membrane protein of large eukaryotic DNA viruses DUF3135 PF11333.8 EAQ93348.1 - 0.2 12.0 3.2 0.22 11.8 0.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3135) Spo7_2_N PF15407.6 EAQ93348.1 - 0.22 11.2 0.0 0.46 10.2 0.0 1.4 1 0 0 1 1 1 0 Sporulation protein family 7 CorA PF01544.18 EAQ93349.1 - 1.3e-36 126.4 1.8 1.5e-34 119.7 1.8 2.1 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein His_Phos_1 PF00300.22 EAQ93349.1 - 0.035 13.8 0.1 0.072 12.8 0.1 1.4 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) Lebercilin PF15619.6 EAQ93349.1 - 0.13 11.9 4.6 0.062 12.9 1.8 1.9 3 0 0 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease Arc_PepC_II PF06847.11 EAQ93349.1 - 0.25 11.9 0.8 7.5 7.1 0.2 2.8 2 1 1 3 3 3 0 Archaeal Peptidase A24 C-terminus Type II DUF3237 PF11578.8 EAQ93351.1 - 2.2e-30 105.5 0.1 2.4e-30 105.3 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) Mob1_phocein PF03637.17 EAQ93352.1 - 6.3e-30 104.4 0.0 1.6e-28 99.8 0.0 2.1 1 1 0 1 1 1 1 Mob1/phocein family Leo1 PF04004.13 EAQ93353.1 - 2.4e-20 73.0 6.9 4.3e-18 65.7 0.1 2.9 2 1 1 3 3 3 2 Leo1-like protein BRO1 PF03097.18 EAQ93354.1 - 0.00054 18.9 0.0 0.00084 18.2 0.0 1.3 1 0 0 1 1 1 1 BRO1-like domain Alg6_Alg8 PF03155.15 EAQ93355.1 - 9.2e-131 437.1 27.6 1.2e-83 281.7 10.5 2.2 2 0 0 2 2 2 2 ALG6, ALG8 glycosyltransferase family SURF4 PF02077.15 EAQ93357.1 - 1.3e-89 300.4 8.7 1.5e-89 300.1 8.7 1.0 1 0 0 1 1 1 1 SURF4 family Zn_clus PF00172.18 EAQ93358.1 - 1.3e-06 28.4 9.8 4.1e-06 26.8 9.8 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BOP1NT PF08145.12 EAQ93359.1 - 2e-102 342.6 6.9 3.2e-102 341.9 6.9 1.3 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.32 EAQ93359.1 - 2e-19 69.5 0.5 2.4e-07 31.3 0.0 5.4 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAQ93359.1 - 2.2e-05 24.7 0.0 0.0022 18.2 0.0 3.7 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EAQ93359.1 - 0.094 11.3 0.0 0.14 10.7 0.0 1.1 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Lipase_GDSL_2 PF13472.6 EAQ93360.1 - 2.8e-24 86.5 2.3 5.3e-24 85.6 2.3 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EAQ93360.1 - 8.8e-07 29.1 0.0 1.4e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DUF3336 PF11815.8 EAQ93362.1 - 3.8e-29 101.2 0.0 2e-28 98.8 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) Patatin PF01734.22 EAQ93362.1 - 2.5e-12 47.4 0.1 4.6e-12 46.5 0.1 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase Helicase_C PF00271.31 EAQ93363.1 - 6.2e-17 61.9 0.0 2.1e-16 60.2 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 EAQ93363.1 - 7.8e-14 51.1 0.8 9.4e-08 31.1 0.3 2.2 1 1 1 2 2 2 2 SNF2 family N-terminal domain HIGH_NTase1_ass PF16581.5 EAQ93363.1 - 0.012 15.6 0.3 0.036 14.1 0.1 1.8 2 0 0 2 2 2 0 Cytidyltransferase-related C-terminal region ERCC3_RAD25_C PF16203.5 EAQ93363.1 - 0.03 13.5 0.0 0.063 12.5 0.0 1.5 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase VMA21 PF09446.10 EAQ93364.1 - 1e-14 54.4 9.1 1.4e-14 53.9 9.1 1.2 1 0 0 1 1 1 1 VMA21-like domain DUF2406 PF10295.9 EAQ93365.1 - 4.9e-28 97.6 1.2 9.8e-28 96.6 0.2 2.1 2 0 0 2 2 2 1 Uncharacterised protein (DUF2406) Ribosomal_L35Ae PF01247.18 EAQ93367.1 - 5.6e-32 109.8 0.1 6.5e-32 109.6 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 EAQ93367.1 - 0.00097 19.3 0.1 0.35 11.1 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain APH PF01636.23 EAQ93369.1 - 3.6e-11 43.5 1.1 5.8e-10 39.5 1.2 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EAQ93369.1 - 0.0056 16.3 0.3 0.088 12.4 0.2 2.3 2 1 0 2 2 2 1 Choline/ethanolamine kinase HMG_box_2 PF09011.10 EAQ93369.1 - 0.12 13.0 0.0 0.28 11.8 0.0 1.5 1 0 0 1 1 1 0 HMG-box domain G6PD_C PF02781.16 EAQ93370.1 - 2.8e-115 384.5 0.0 4.7e-115 383.7 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 EAQ93370.1 - 3.2e-52 177.7 0.1 6e-52 176.8 0.1 1.5 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Med14 PF08638.11 EAQ93371.1 - 1.1e-68 230.4 0.0 1.1e-68 230.4 0.0 2.4 2 0 0 2 2 2 1 Mediator complex subunit MED14 SpoIIIAH PF12685.7 EAQ93371.1 - 0.055 13.3 4.3 0.088 12.6 4.3 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein TFIIA PF03153.13 EAQ93371.1 - 0.14 12.1 37.6 0.24 11.4 37.6 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Amino_oxidase PF01593.24 EAQ93372.1 - 1e-23 84.4 0.0 1.3e-23 84.1 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EAQ93372.1 - 6.2e-10 39.2 0.0 3.1e-09 36.9 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EAQ93372.1 - 1.2e-08 35.0 1.3 1.6e-05 24.6 0.1 2.8 2 1 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EAQ93372.1 - 0.00011 21.6 0.0 0.0062 15.8 0.0 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EAQ93372.1 - 0.0041 16.4 0.0 0.0071 15.6 0.0 1.2 1 0 0 1 1 1 1 Thi4 family MCRA PF06100.11 EAQ93372.1 - 0.022 13.6 0.0 0.031 13.1 0.0 1.2 1 0 0 1 1 1 0 MCRA family Pyr_redox PF00070.27 EAQ93372.1 - 0.15 12.7 0.1 1.9 9.1 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase zf-CCCH_2 PF14608.6 EAQ93373.1 - 2.6e-12 46.7 53.9 2.8e-05 24.4 11.9 5.5 5 1 0 5 5 5 5 RNA-binding, Nab2-type zinc finger Glyco_hydro_20 PF00728.22 EAQ93374.1 - 3.8e-86 289.7 0.0 4.7e-86 289.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 EAQ93374.1 - 2.1e-33 115.9 0.0 4.9e-33 114.7 0.0 1.7 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 EAQ93374.1 - 1.2e-06 29.3 0.0 0.001 19.8 0.0 2.4 2 0 0 2 2 2 2 Glycosyl hydrolase family 20, domain 2 p450 PF00067.22 EAQ93375.1 - 3.1e-61 207.5 0.0 4.2e-61 207.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Aminotran_1_2 PF00155.21 EAQ93376.1 - 1.6e-16 60.5 0.0 2e-16 60.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 EAQ93376.1 - 1.4e-08 34.0 0.0 1.9e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase UPF0139 PF03669.13 EAQ93378.1 - 0.12 12.2 0.2 0.22 11.4 0.2 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0139) Glyco_hydro_16 PF00722.21 EAQ93379.1 - 1.3e-43 148.5 0.4 2.1e-43 147.8 0.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Topoisom_I PF01028.20 EAQ93380.1 - 8.9e-96 319.6 6.8 2.5e-95 318.2 6.8 1.8 1 0 0 1 1 1 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.15 EAQ93380.1 - 3.7e-95 317.5 3.7 3.7e-95 317.5 3.7 2.5 3 0 0 3 3 3 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topo_C_assoc PF14370.6 EAQ93380.1 - 2.4e-30 104.3 0.3 1e-29 102.2 0.1 2.3 2 0 0 2 2 2 1 C-terminal topoisomerase domain DUF4094 PF13334.6 EAQ93380.1 - 0.35 11.3 1.7 1.5 9.3 1.7 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) ATP-synt PF00231.19 EAQ93381.1 - 3.9e-79 266.3 0.5 4.7e-79 266.0 0.5 1.0 1 0 0 1 1 1 1 ATP synthase Amino_oxidase PF01593.24 EAQ93382.1 - 2.9e-84 284.0 0.1 5e-70 237.0 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase SWIRM PF04433.17 EAQ93382.1 - 9.1e-15 54.8 0.0 1.9e-14 53.8 0.0 1.5 1 0 0 1 1 1 1 SWIRM domain NAD_binding_8 PF13450.6 EAQ93382.1 - 7.5e-08 32.5 0.0 1.7e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HMG_box PF00505.19 EAQ93382.1 - 3.2e-06 27.5 2.3 1.3e-05 25.6 2.3 2.1 1 1 0 1 1 1 1 HMG (high mobility group) box Pyr_redox_2 PF07992.14 EAQ93382.1 - 0.00055 19.2 0.0 0.0012 18.2 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EAQ93382.1 - 0.0009 18.9 4.0 0.0014 18.3 0.2 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase HMG_box_2 PF09011.10 EAQ93382.1 - 0.0012 19.3 1.2 0.0026 18.3 1.2 1.5 1 0 0 1 1 1 1 HMG-box domain OmdA PF13376.6 EAQ93382.1 - 0.084 12.9 0.9 0.18 11.8 0.9 1.6 1 0 0 1 1 1 0 Bacteriocin-protection, YdeI or OmpD-Associated Sec1 PF00995.23 EAQ93383.1 - 4.8e-126 422.3 0.0 5.4e-126 422.1 0.0 1.0 1 0 0 1 1 1 1 Sec1 family UQ_con PF00179.26 EAQ93384.1 - 3.4e-13 49.4 0.0 3.6e-13 49.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Pkinase PF00069.25 EAQ93385.1 - 1.4e-68 231.1 0.0 1.8e-68 230.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ93385.1 - 6.3e-33 114.1 0.0 1e-32 113.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAQ93385.1 - 2.2e-07 30.5 0.0 3.3e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EAQ93385.1 - 0.00032 20.1 0.1 0.00054 19.4 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EAQ93385.1 - 0.0011 17.8 0.0 0.0024 16.7 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase YrbL-PhoP_reg PF10707.9 EAQ93385.1 - 0.0039 16.7 0.1 0.017 14.6 0.0 2.1 3 0 0 3 3 3 1 PhoP regulatory network protein YrbL PFL-like PF02901.15 EAQ93386.1 - 0.28 9.7 1.8 0.4 9.3 1.8 1.1 1 0 0 1 1 1 0 Pyruvate formate lyase-like CCDC53 PF10152.9 EAQ93386.1 - 0.44 11.0 1.9 1 9.7 1.9 1.5 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex tRNA-synt_His PF13393.6 EAQ93387.1 - 2.1e-31 109.3 0.0 3.2e-25 89.1 0.0 2.3 2 0 0 2 2 2 2 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 EAQ93387.1 - 4.5e-13 49.2 0.0 8.5e-13 48.3 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain HGTP_anticodon2 PF12745.7 EAQ93387.1 - 0.0013 18.3 0.0 0.002 17.7 0.0 1.2 1 0 0 1 1 1 1 Anticodon binding domain of tRNAs tRNA-synt_2 PF00152.20 EAQ93387.1 - 0.093 11.8 0.0 0.4 9.7 0.0 1.9 2 0 0 2 2 2 0 tRNA synthetases class II (D, K and N) AIRC PF00731.20 EAQ93387.1 - 0.15 11.6 0.0 1.7 8.2 0.0 2.3 2 0 0 2 2 2 0 AIR carboxylase tRNA-synt_2b PF00587.25 EAQ93387.1 - 0.16 12.0 0.0 0.43 10.5 0.0 1.8 1 1 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) ABC_membrane PF00664.23 EAQ93388.1 - 2.1e-66 224.4 26.7 1e-41 143.4 20.6 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EAQ93388.1 - 1.5e-44 151.9 0.0 3.7e-31 108.5 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EAQ93388.1 - 7.5e-10 38.6 1.1 0.0042 16.6 0.0 3.2 2 1 1 3 3 3 3 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 EAQ93388.1 - 0.0025 18.0 2.0 0.95 9.7 0.3 3.9 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.6 EAQ93388.1 - 0.0027 18.1 0.2 0.015 15.7 0.1 2.3 2 1 0 2 2 2 1 AAA ATPase domain ABC_ATPase PF09818.9 EAQ93388.1 - 0.003 16.4 0.1 0.035 12.9 0.0 2.1 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_22 PF13401.6 EAQ93388.1 - 0.0065 16.7 0.1 0.098 12.9 0.1 2.7 2 1 0 2 2 2 1 AAA domain AAA_15 PF13175.6 EAQ93388.1 - 0.0089 15.8 0.2 0.015 15.1 0.2 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 EAQ93388.1 - 0.014 15.2 0.3 0.1 12.4 0.2 2.2 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 EAQ93388.1 - 0.029 14.1 0.3 0.43 10.3 0.1 2.8 2 1 0 2 2 2 0 AAA domain AAA PF00004.29 EAQ93388.1 - 0.041 14.3 0.2 58 4.1 0.0 3.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 EAQ93388.1 - 0.042 13.6 0.2 0.13 12.1 0.2 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.6 EAQ93388.1 - 0.11 12.0 0.0 0.91 9.1 0.0 2.4 3 0 0 3 3 3 0 AAA domain dCMP_cyt_deam_1 PF00383.23 EAQ93389.1 - 7.7e-15 54.6 0.0 9.5e-15 54.3 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 EAQ93389.1 - 2e-09 37.7 2.0 9.7e-08 32.3 0.1 2.1 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.6 EAQ93389.1 - 0.0013 18.4 0.4 0.97 9.0 0.0 2.1 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases FYVE PF01363.21 EAQ93390.1 - 7.8e-21 74.0 0.7 7.8e-21 74.0 0.7 3.0 3 0 0 3 3 3 1 FYVE zinc finger zf-RING_2 PF13639.6 EAQ93390.1 - 1.2e-06 28.7 4.8 1.2e-06 28.7 4.8 3.9 4 0 0 4 4 4 1 Ring finger domain zf-C3HC4_2 PF13923.6 EAQ93390.1 - 4.5e-06 26.4 3.4 4.5e-06 26.4 3.4 4.0 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EAQ93390.1 - 4.9e-05 23.0 4.6 4.9e-05 23.0 4.6 2.6 3 0 0 3 3 3 1 RING-like zinc finger zf-C3HC4 PF00097.25 EAQ93390.1 - 0.00043 20.1 2.8 0.00043 20.1 2.8 3.7 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EAQ93390.1 - 0.00047 20.1 2.9 0.00047 20.1 2.9 3.8 3 0 0 3 3 3 1 RING-type zinc-finger DZR PF12773.7 EAQ93390.1 - 0.0035 17.3 7.9 0.18 11.9 5.0 3.1 2 0 0 2 2 2 1 Double zinc ribbon Rad50_zn_hook PF04423.14 EAQ93390.1 - 0.005 16.7 2.9 0.024 14.5 0.6 2.4 2 0 0 2 2 2 1 Rad50 zinc hook motif FYVE_2 PF02318.16 EAQ93390.1 - 0.0076 16.5 6.3 0.011 16.0 0.3 2.5 2 0 0 2 2 2 1 FYVE-type zinc finger zf-RING-like PF08746.11 EAQ93390.1 - 0.017 15.5 2.9 0.017 15.5 2.9 3.2 4 0 0 4 4 2 0 RING-like domain Zn-C2H2_12 PF18112.1 EAQ93390.1 - 0.37 11.3 3.7 1.9 9.0 0.1 2.9 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zf-piccolo PF05715.13 EAQ93390.1 - 0.64 10.2 13.4 0.46 10.7 5.1 3.3 3 0 0 3 3 3 0 Piccolo Zn-finger zinc_ribbon_2 PF13240.6 EAQ93390.1 - 1 9.2 8.3 3.3 7.5 0.2 3.6 3 0 0 3 3 3 0 zinc-ribbon domain zf-C2H2_6 PF13912.6 EAQ93390.1 - 3.2 7.9 10.3 8 6.6 0.0 4.5 5 0 0 5 5 4 0 C2H2-type zinc finger Elf1 PF05129.13 EAQ93390.1 - 3.6 7.7 12.7 0.93 9.6 2.4 3.6 4 0 0 4 4 4 0 Transcription elongation factor Elf1 like SH3BGR PF04908.15 EAQ93391.1 - 0.00013 22.1 3.0 0.00029 21.0 0.0 3.0 3 1 0 3 3 3 1 SH3-binding, glutamic acid-rich protein PPP4R2 PF09184.11 EAQ93391.1 - 0.0056 16.3 15.4 0.0056 16.3 15.4 2.2 2 0 0 2 2 2 1 PPP4R2 LAP1C PF05609.12 EAQ93391.1 - 8.4 5.4 31.0 12 4.8 29.3 1.8 2 0 0 2 2 2 0 Lamina-associated polypeptide 1C (LAP1C) Apc15p PF05841.11 EAQ93392.1 - 3.5 8.5 9.1 1.3 9.9 6.1 1.7 1 1 0 2 2 2 0 Apc15p protein AAA PF00004.29 EAQ93394.1 - 4.7e-49 166.2 0.0 2.5e-43 147.7 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EAQ93394.1 - 7.8e-05 23.1 0.4 0.021 15.2 0.0 3.4 2 1 1 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 EAQ93394.1 - 0.00019 21.3 0.0 0.00054 19.7 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Parvo_NS1 PF01057.17 EAQ93394.1 - 0.00082 18.5 0.0 0.0014 17.8 0.0 1.2 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_2 PF07724.14 EAQ93394.1 - 0.004 17.3 0.0 0.0095 16.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_25 PF13481.6 EAQ93394.1 - 0.0063 16.1 0.0 0.026 14.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 EAQ93394.1 - 0.0077 16.6 0.0 0.04 14.3 0.0 2.3 3 0 0 3 3 1 1 RNA helicase IstB_IS21 PF01695.17 EAQ93394.1 - 0.0079 15.9 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.6 EAQ93394.1 - 0.009 16.3 0.0 0.038 14.3 0.0 2.0 1 1 1 2 2 2 1 AAA domain TIP49 PF06068.13 EAQ93394.1 - 0.013 14.8 0.0 0.02 14.1 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_5 PF07728.14 EAQ93394.1 - 0.028 14.4 0.0 0.14 12.2 0.0 2.2 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 EAQ93394.1 - 0.03 13.7 0.1 0.058 12.8 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ATPase PF06745.13 EAQ93394.1 - 0.032 13.6 0.0 0.087 12.2 0.0 1.6 2 0 0 2 2 2 0 KaiC AAA_7 PF12775.7 EAQ93394.1 - 0.056 13.0 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region PhoH PF02562.16 EAQ93394.1 - 0.07 12.6 0.2 0.18 11.2 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein AAA_18 PF13238.6 EAQ93394.1 - 0.098 13.2 0.0 0.2 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EAQ93394.1 - 0.11 12.8 0.0 0.26 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 EAQ93394.1 - 0.11 11.7 0.1 0.23 10.6 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) TsaE PF02367.17 EAQ93394.1 - 0.11 12.5 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activat PF00158.26 EAQ93394.1 - 0.15 11.8 0.0 1.6 8.4 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_lid_3 PF17862.1 EAQ93394.1 - 0.19 11.6 2.8 1.2 9.0 0.0 3.0 3 0 0 3 3 3 0 AAA+ lid domain Abhydro_lipase PF04083.16 EAQ93395.1 - 6e-20 70.6 0.0 1.4e-19 69.4 0.0 1.7 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 EAQ93395.1 - 0.00024 20.8 0.1 0.0005 19.8 0.1 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EAQ93395.1 - 0.0056 16.0 0.0 0.01 15.1 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF3899 PF13038.6 EAQ93395.1 - 0.0073 16.8 0.1 0.027 15.0 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3899) Glyco_hydro_125 PF06824.11 EAQ93396.1 - 5.1e-184 612.0 0.3 7.9e-184 611.3 0.3 1.3 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) DUF778 PF05608.12 EAQ93396.1 - 0.22 11.9 1.8 7.4 6.9 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF778) AICARFT_IMPCHas PF01808.18 EAQ93397.1 - 9.3e-92 307.6 0.0 1.2e-91 307.2 0.0 1.2 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 EAQ93397.1 - 4.4e-23 81.3 0.0 8.5e-23 80.4 0.0 1.5 1 0 0 1 1 1 1 MGS-like domain RRM_1 PF00076.22 EAQ93398.1 - 8.3e-13 48.0 0.0 7.6e-05 22.4 0.0 3.0 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EAQ93398.1 - 0.088 12.9 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif Striatin PF08232.12 EAQ93398.1 - 0.74 10.4 10.0 0.11 13.1 0.8 2.2 2 0 0 2 2 2 0 Striatin family Peptidase_S49_N PF08496.10 EAQ93398.1 - 0.96 9.5 4.0 0.88 9.6 0.4 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Proteasom_Rpn13 PF04683.13 EAQ93399.1 - 1.8e-24 86.0 0.0 2.8e-24 85.4 0.0 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor RPN13_C PF16550.5 EAQ93399.1 - 7.5e-12 45.4 1.2 3e-10 40.3 1.2 2.3 1 1 0 1 1 1 1 UCH-binding domain PAD_porph PF04371.15 EAQ93399.1 - 0.21 10.9 0.0 0.3 10.3 0.0 1.1 1 0 0 1 1 1 0 Porphyromonas-type peptidyl-arginine deiminase DUF826 PF05696.11 EAQ93399.1 - 0.46 10.6 3.1 3.6 7.7 0.2 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF826) Anp1 PF03452.14 EAQ93400.1 - 2.4e-106 355.0 0.0 2.8e-106 354.8 0.0 1.0 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.26 EAQ93400.1 - 0.0018 18.1 0.0 0.0029 17.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Tom37 PF10568.9 EAQ93400.1 - 0.081 13.2 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein UQ_con PF00179.26 EAQ93401.1 - 1.6e-31 108.8 0.0 1.9e-31 108.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EAQ93401.1 - 0.12 12.7 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 RWD domain Cgr1 PF03879.14 EAQ93403.1 - 4.4e-31 107.4 24.9 6.1e-31 107.0 24.9 1.1 1 0 0 1 1 1 1 Cgr1 family RR_TM4-6 PF06459.12 EAQ93403.1 - 1.6 8.5 10.2 1.8 8.3 10.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Med9 PF07544.13 EAQ93404.1 - 0.01 15.9 0.6 0.031 14.4 0.6 1.8 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 DotU PF09850.9 EAQ93404.1 - 0.31 10.7 1.8 0.38 10.5 0.1 2.0 2 0 0 2 2 2 0 Type VI secretion system protein DotU DHR10 PF18595.1 EAQ93404.1 - 0.34 11.0 6.4 0.16 12.0 2.6 2.0 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain KxDL PF10241.9 EAQ93404.1 - 0.58 10.5 2.1 3.7 7.9 0.3 2.4 1 1 1 2 2 2 0 Uncharacterized conserved protein Jnk-SapK_ap_N PF09744.9 EAQ93404.1 - 1.1 9.4 4.0 0.55 10.4 1.0 1.8 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF3818 PF12825.7 EAQ93405.1 - 2.9e-130 434.2 2.2 4.4e-130 433.6 2.2 1.3 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 EAQ93405.1 - 4.8e-34 117.2 0.6 9e-34 116.3 0.6 1.4 1 0 0 1 1 1 1 PX-associated FAD_binding_2 PF00890.24 EAQ93406.1 - 4.9e-123 411.3 4.4 6.1e-123 411.0 4.4 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 EAQ93406.1 - 3.8e-45 153.0 0.8 5.7e-45 152.4 0.8 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 EAQ93406.1 - 3e-06 26.7 0.3 0.0016 17.7 0.1 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EAQ93406.1 - 0.00013 21.2 1.2 0.045 12.8 1.9 2.4 2 0 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.17 EAQ93406.1 - 0.00026 20.3 0.2 0.12 11.6 0.1 2.3 2 0 0 2 2 2 2 Thi4 family FAD_binding_3 PF01494.19 EAQ93406.1 - 0.0028 17.0 3.4 0.003 16.8 0.1 2.4 3 0 0 3 3 3 1 FAD binding domain DAO PF01266.24 EAQ93406.1 - 0.16 11.5 1.6 0.3 10.6 1.6 1.6 1 1 0 1 1 1 0 FAD dependent oxidoreductase DUF5519 PF17648.1 EAQ93407.1 - 0.19 11.6 0.2 0.19 11.6 0.2 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5519) DUF3405 PF11885.8 EAQ93408.1 - 7.1e-205 681.5 2.4 7.1e-205 681.5 2.4 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3405) DUF3740 PF12548.8 EAQ93408.1 - 0.034 14.6 1.6 0.36 11.3 0.0 2.7 3 0 0 3 3 3 0 Sulfatase protein EMP24_GP25L PF01105.24 EAQ93409.1 - 1.2e-46 159.0 0.0 1.3e-46 158.8 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Arf PF00025.21 EAQ93410.1 - 1.2e-78 262.6 0.2 1.3e-78 262.4 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EAQ93410.1 - 2.2e-14 53.7 0.0 3e-14 53.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 EAQ93410.1 - 2.4e-13 49.9 0.0 3e-13 49.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 EAQ93410.1 - 3.6e-13 49.4 1.0 5e-09 35.8 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 EAQ93410.1 - 7.9e-13 48.3 0.0 8.5e-13 48.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 EAQ93410.1 - 1.4e-10 41.0 0.0 1.6e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EAQ93410.1 - 1e-05 25.6 0.0 1.6e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 EAQ93410.1 - 0.0025 17.2 0.2 0.0071 15.7 0.1 1.6 2 0 0 2 2 2 1 6-phosphofructo-2-kinase AAA_2 PF07724.14 EAQ93411.1 - 1.1e-45 155.8 0.0 2.2e-44 151.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 EAQ93411.1 - 7.7e-36 122.2 2.3 7.7e-36 122.2 2.3 2.6 1 1 1 2 2 2 1 AAA lid domain ClpB_D2-small PF10431.9 EAQ93411.1 - 4.5e-25 87.5 0.1 1.7e-24 85.6 0.1 2.1 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 EAQ93411.1 - 7e-19 68.6 0.1 5.8e-10 39.7 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EAQ93411.1 - 5.8e-12 45.8 0.0 7.3e-09 35.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EAQ93411.1 - 2.6e-09 37.7 4.3 0.004 17.5 0.6 4.1 2 2 1 3 3 3 2 AAA ATPase domain Sigma54_activat PF00158.26 EAQ93411.1 - 5.1e-07 29.5 0.4 0.00029 20.6 0.0 2.6 2 1 0 2 2 2 1 Sigma-54 interaction domain ATPase_2 PF01637.18 EAQ93411.1 - 6.9e-07 29.4 0.7 1.2 9.0 0.1 4.0 3 1 0 3 3 3 2 ATPase domain predominantly from Archaea AAA_22 PF13401.6 EAQ93411.1 - 1.1e-06 29.0 4.3 0.034 14.4 0.1 3.9 3 2 0 3 3 2 2 AAA domain AAA_14 PF13173.6 EAQ93411.1 - 4.3e-06 26.8 0.0 0.065 13.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 EAQ93411.1 - 1.5e-05 25.0 0.0 0.18 11.7 0.0 2.6 2 0 0 2 2 2 2 NACHT domain TniB PF05621.11 EAQ93411.1 - 9e-05 22.0 0.0 0.02 14.3 0.0 3.4 3 1 0 3 3 2 1 Bacterial TniB protein IstB_IS21 PF01695.17 EAQ93411.1 - 9.3e-05 22.2 0.2 0.3 10.8 0.0 2.8 2 1 0 2 2 2 2 IstB-like ATP binding protein AAA_7 PF12775.7 EAQ93411.1 - 0.00012 21.6 0.0 0.18 11.3 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region RsgA_GTPase PF03193.16 EAQ93411.1 - 0.0002 21.3 0.1 0.9 9.4 0.0 2.8 2 1 0 2 2 2 2 RsgA GTPase RNA_helicase PF00910.22 EAQ93411.1 - 0.0013 19.0 0.0 0.47 10.9 0.0 3.0 2 1 0 2 2 2 1 RNA helicase AAA_18 PF13238.6 EAQ93411.1 - 0.0016 19.0 3.2 0.13 12.8 0.0 3.6 4 0 0 4 4 3 1 AAA domain AAA_33 PF13671.6 EAQ93411.1 - 0.0053 16.9 0.0 2.7 8.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.22 EAQ93411.1 - 0.0053 16.4 0.1 0.3 10.7 0.0 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_28 PF13521.6 EAQ93411.1 - 0.0061 16.8 1.3 7.3 6.8 0.0 3.8 3 1 0 3 3 3 0 AAA domain AAA_24 PF13479.6 EAQ93411.1 - 0.0072 16.1 0.0 0.55 9.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 EAQ93411.1 - 0.0097 16.4 0.6 2 8.9 0.0 3.3 3 0 0 3 3 3 1 ABC transporter Roc PF08477.13 EAQ93411.1 - 0.0098 16.1 0.1 1.8 8.8 0.0 2.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase TsaE PF02367.17 EAQ93411.1 - 0.014 15.4 0.1 4 7.5 0.0 2.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 EAQ93411.1 - 0.023 14.3 0.1 0.64 9.6 0.0 2.8 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 EAQ93411.1 - 0.029 13.6 0.3 2.4 7.3 0.2 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF815) Bac_DnaA PF00308.18 EAQ93411.1 - 0.039 13.8 0.0 3.4 7.4 0.0 2.6 2 0 0 2 2 2 0 Bacterial dnaA protein Mg_chelatase PF01078.21 EAQ93411.1 - 0.04 13.3 0.1 3 7.2 0.0 3.0 2 1 0 2 2 2 0 Magnesium chelatase, subunit ChlI NTPase_1 PF03266.15 EAQ93411.1 - 0.041 13.8 0.1 0.54 10.1 0.0 2.6 2 0 0 2 2 2 0 NTPase Zeta_toxin PF06414.12 EAQ93411.1 - 0.042 13.1 0.0 2.5 7.3 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin UvrD-helicase PF00580.21 EAQ93411.1 - 0.061 12.8 2.3 0.9 9.0 0.1 2.3 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain Seryl_tRNA_N PF02403.22 EAQ93411.1 - 0.073 13.3 13.3 0.23 11.7 12.3 2.3 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain AAA_23 PF13476.6 EAQ93411.1 - 0.076 13.5 7.6 1.5 9.3 4.6 3.1 3 0 0 3 3 3 0 AAA domain AAA_19 PF13245.6 EAQ93411.1 - 0.086 13.2 1.4 2.2 8.6 0.2 3.1 2 2 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 EAQ93411.1 - 0.086 12.6 0.1 0.89 9.3 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein PduV-EutP PF10662.9 EAQ93411.1 - 0.12 12.2 0.0 1.6 8.5 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ADIP PF11559.8 EAQ93411.1 - 2.6 8.1 13.9 5.3 7.1 13.9 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding OEP PF02321.18 EAQ93411.1 - 4 7.2 10.4 10 5.9 10.4 1.6 1 0 0 1 1 1 0 Outer membrane efflux protein GrpE PF01025.19 EAQ93411.1 - 5.3 6.7 9.2 12 5.5 9.2 1.6 1 0 0 1 1 1 0 GrpE UPF0242 PF06785.11 EAQ93411.1 - 5.4 7.1 11.2 11 6.1 11.2 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus APG6_N PF17675.1 EAQ93411.1 - 8.2 7.0 17.6 18 5.9 17.6 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region Sld5 PF05916.11 EAQ93412.1 - 5.4e-13 49.3 0.0 7.5e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein FliT PF05400.13 EAQ93412.1 - 0.096 13.5 0.0 0.6 11.0 0.0 2.2 2 0 0 2 2 2 0 Flagellar protein FliT Sulfate_transp PF00916.20 EAQ93413.1 - 4.2e-50 170.6 6.8 4.2e-50 170.6 6.8 1.5 1 1 1 2 2 2 1 Sulfate permease family DUF3188 PF11384.8 EAQ93413.1 - 1.1 9.0 0.0 1.1 9.0 0.0 3.8 5 0 0 5 5 5 0 Protein of unknown function (DUF3188) Kinesin PF00225.23 EAQ93415.1 - 1.2e-94 317.0 0.1 2e-94 316.2 0.1 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EAQ93415.1 - 1.1e-17 64.3 0.0 4e-17 62.5 0.0 2.0 2 0 0 2 2 2 1 Microtubule binding PKcGMP_CC PF16808.5 EAQ93415.1 - 0.022 14.6 0.6 0.022 14.6 0.6 4.2 4 0 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Tho2 PF11262.8 EAQ93415.1 - 0.037 13.2 2.1 0.075 12.2 2.1 1.4 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DASH_Spc34 PF08657.10 EAQ93415.1 - 0.082 12.7 8.1 0.12 12.1 0.0 2.6 2 0 0 2 2 2 0 DASH complex subunit Spc34 DUF5593 PF18007.1 EAQ93415.1 - 0.74 10.5 4.6 26 5.6 0.1 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF5593) DUF4407 PF14362.6 EAQ93415.1 - 1.2 8.4 17.4 0.2 11.0 4.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) TFB6 PF17110.5 EAQ93415.1 - 1.3 8.8 5.5 3.4 7.4 5.5 1.7 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH OmpH PF03938.14 EAQ93415.1 - 1.9 8.8 10.8 3.7 7.9 4.5 2.8 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) Microtub_bind PF13931.6 EAQ93415.1 - 4.1 7.8 7.1 3.3 8.1 3.3 2.7 2 0 0 2 2 2 0 Kinesin-associated microtubule-binding p450 PF00067.22 EAQ93417.1 - 2.2e-68 231.1 0.0 2.8e-68 230.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Get5_bdg PF16843.5 EAQ93417.1 - 0.061 12.8 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Binding domain to Get4 on Get5, Golgi to ER traffic protein HSP70 PF00012.20 EAQ93418.1 - 4.8e-175 583.2 6.1 6.5e-175 582.8 6.1 1.2 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EAQ93418.1 - 1.2e-19 70.3 0.2 1.8e-19 69.7 0.2 1.2 1 0 0 1 1 1 1 MreB/Mbl protein FIVAR PF07554.13 EAQ93418.1 - 0.071 13.9 0.5 5.7 7.8 0.1 2.7 2 0 0 2 2 2 0 FIVAR domain TPP_enzyme_N PF02776.18 EAQ93418.1 - 0.085 12.5 0.3 0.3 10.7 0.0 1.9 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain StbA PF06406.11 EAQ93418.1 - 0.1 11.8 0.1 0.27 10.4 0.0 1.7 2 0 0 2 2 2 0 StbA protein Peroxin-13_N PF04088.13 EAQ93419.1 - 6.1e-51 172.5 0.0 8.5e-51 172.1 0.0 1.2 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.17 EAQ93419.1 - 2.5e-07 30.3 0.0 4.7e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EAQ93419.1 - 3.4e-05 23.4 0.0 5.7e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EAQ93419.1 - 0.0001 22.1 0.0 0.00017 21.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain TFIIA PF03153.13 EAQ93420.1 - 5.4e-89 300.1 2.3 6.2e-89 299.9 2.3 1.0 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DNA_pol_phi PF04931.13 EAQ93420.1 - 1.7 6.6 5.1 2.3 6.2 5.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi Roughex PF06020.11 EAQ93420.1 - 5.2 6.1 6.1 10 5.1 6.1 1.4 1 0 0 1 1 1 0 Drosophila roughex protein CENP-B_dimeris PF09026.10 EAQ93420.1 - 7.1 7.1 11.0 13 6.2 11.0 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF2937 PF11157.8 EAQ93420.1 - 7.5 6.2 6.5 2.8 7.6 3.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) ANAPC4_WD40 PF12894.7 EAQ93421.1 - 3.4e-17 62.5 3.8 4e-05 23.8 0.2 4.4 3 1 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EAQ93421.1 - 2.8e-16 59.6 18.4 0.00033 21.4 0.1 6.3 7 0 0 7 7 7 5 WD domain, G-beta repeat Ge1_WD40 PF16529.5 EAQ93421.1 - 7.1e-06 25.2 0.0 0.00045 19.3 0.0 3.2 2 1 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 EAQ93421.1 - 1.1e-05 25.5 0.1 0.00049 20.0 0.0 2.4 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Kelch_4 PF13418.6 EAQ93422.1 - 1.6e-29 101.7 6.8 3.6e-08 33.3 0.0 5.0 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_6 PF13964.6 EAQ93422.1 - 6.6e-23 80.2 3.6 7.4e-05 22.9 0.0 5.1 3 1 2 5 5 5 4 Kelch motif Kelch_5 PF13854.6 EAQ93422.1 - 4.2e-22 77.7 7.3 6.2e-06 26.1 0.0 4.9 5 0 0 5 5 5 4 Kelch motif Kelch_1 PF01344.25 EAQ93422.1 - 4.2e-20 71.1 2.3 7.3e-05 22.3 0.0 4.9 5 0 0 5 5 5 3 Kelch motif Kelch_2 PF07646.15 EAQ93422.1 - 1.6e-18 65.8 3.8 5.5e-05 23.0 0.0 4.7 4 0 0 4 4 4 4 Kelch motif Kelch_3 PF13415.6 EAQ93422.1 - 1.9e-17 63.1 17.9 2e-08 34.3 0.2 5.8 7 0 0 7 7 7 4 Galactose oxidase, central domain BTB PF00651.31 EAQ93422.1 - 1.9e-08 34.5 0.0 3.4e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2_aberr PF17017.5 EAQ93423.1 - 1.1e-05 25.7 0.9 0.023 14.8 0.1 2.4 2 0 0 2 2 2 2 Aberrant zinc-finger zf-C2H2_4 PF13894.6 EAQ93423.1 - 0.00017 22.2 19.5 0.023 15.5 1.2 4.1 4 0 0 4 4 4 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EAQ93423.1 - 0.00089 19.6 6.8 0.022 15.2 1.1 3.0 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 EAQ93423.1 - 0.0095 16.3 15.7 0.1 13.1 1.5 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 EAQ93423.1 - 0.93 9.9 9.6 0.84 10.0 0.3 3.6 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding DUF3254 PF11630.8 EAQ93424.1 - 0.015 15.4 0.0 0.02 15.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3254) HIG_1_N PF04588.13 EAQ93425.1 - 1.4e-05 25.2 3.4 1.4e-05 25.2 3.4 2.2 2 0 0 2 2 2 1 Hypoxia induced protein conserved region DUF1689 PF07954.11 EAQ93425.1 - 0.018 15.5 0.2 0.41 11.0 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1689) Kelch_5 PF13854.6 EAQ93426.1 - 8.9e-39 130.9 13.1 1e-06 28.6 0.2 6.2 6 0 0 6 6 6 6 Kelch motif Kelch_1 PF01344.25 EAQ93426.1 - 1.3e-38 130.4 17.1 1e-08 34.6 1.9 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 EAQ93426.1 - 6e-36 122.1 22.3 2e-08 34.3 0.2 7.1 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_4 PF13418.6 EAQ93426.1 - 1.1e-35 121.4 15.7 3.2e-06 27.1 0.3 6.3 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_6 PF13964.6 EAQ93426.1 - 1e-32 111.3 16.2 1.5e-06 28.3 0.0 6.3 4 2 2 6 6 6 5 Kelch motif Kelch_2 PF07646.15 EAQ93426.1 - 1e-31 107.7 14.4 6.1e-09 35.5 0.6 6.4 6 0 0 6 6 6 6 Kelch motif Dus PF01207.17 EAQ93427.1 - 6.3e-32 110.9 0.0 3.7e-22 78.8 0.0 2.4 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) zf-CCCH PF00642.24 EAQ93427.1 - 0.0054 16.6 6.0 0.29 11.1 1.1 2.6 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EAQ93427.1 - 0.33 11.1 11.4 0.15 12.1 2.0 2.8 2 0 0 2 2 2 0 Zinc finger domain Pro_isomerase PF00160.21 EAQ93428.1 - 1.6e-24 87.0 0.0 1.9e-24 86.7 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 EAQ93430.1 - 8.1e-58 192.2 4.7 1.1e-13 50.8 0.0 5.5 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TEA PF01285.18 EAQ93430.1 - 4.9e-10 39.3 0.0 1.3e-09 38.0 0.0 1.8 1 0 0 1 1 1 1 TEA/ATTS domain RRM_occluded PF16842.5 EAQ93430.1 - 2.2e-05 24.2 0.1 0.72 9.8 0.0 4.6 5 0 0 5 5 5 1 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 EAQ93430.1 - 0.0023 17.9 0.1 24 5.0 0.0 4.4 4 0 0 4 4 4 0 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 EAQ93430.1 - 0.018 15.1 0.0 22 5.2 0.0 3.6 3 0 0 3 3 3 0 RNA recognition motif Limkain-b1 PF11608.8 EAQ93430.1 - 0.052 13.6 0.1 31 4.7 0.0 4.1 4 0 0 4 4 4 0 Limkain b1 Smg4_UPF3 PF03467.15 EAQ93430.1 - 0.053 13.5 1.0 0.77 9.7 0.0 2.9 3 0 0 3 3 3 0 Smg-4/UPF3 family Nup35_RRM PF05172.13 EAQ93430.1 - 0.16 11.9 0.0 1.1 9.2 0.0 2.4 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Dynein_light PF01221.18 EAQ93431.1 - 9.9e-11 41.8 1.7 1.5e-10 41.3 1.7 1.2 1 0 0 1 1 1 1 Dynein light chain type 1 DUF3452 PF11934.8 EAQ93431.1 - 0.089 12.4 0.1 0.11 12.0 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3452) DUF3915 PF13054.6 EAQ93432.1 - 0.0052 16.8 6.0 0.011 15.7 6.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3915) Apis_Csd PF11671.8 EAQ93432.1 - 8.7 6.3 9.7 20 5.2 9.7 1.5 1 0 0 1 1 1 0 Complementary sex determiner protein LRR_6 PF13516.6 EAQ93433.1 - 0.13 12.4 0.1 0.27 11.4 0.1 1.5 1 0 0 1 1 1 0 Leucine Rich repeat Methyltransf_16 PF10294.9 EAQ93435.1 - 9.3e-21 74.3 0.0 1.5e-20 73.7 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 EAQ93435.1 - 0.00026 20.8 0.0 0.00045 20.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Dehyd-heme_bind PF09098.10 EAQ93435.1 - 0.069 12.8 0.1 0.12 12.0 0.1 1.3 1 0 0 1 1 1 0 Quinohemoprotein amine dehydrogenase A, alpha subunit, haem binding MTS PF05175.14 EAQ93435.1 - 0.09 12.3 0.0 1.1 8.8 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase small domain HCV_NS5a_1b PF08301.13 EAQ93437.1 - 0.027 15.0 0.1 0.043 14.4 0.1 1.4 1 0 0 1 1 1 0 Hepatitis C virus non-structural 5a domain 1b HSP70 PF00012.20 EAQ93440.1 - 6e-225 748.0 5.7 6.8e-225 747.8 5.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EAQ93440.1 - 6.1e-17 61.4 0.7 4.5e-16 58.6 0.2 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 EAQ93440.1 - 0.0004 20.2 0.0 0.00094 19.0 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.10 EAQ93440.1 - 0.024 13.6 0.6 0.17 10.9 0.3 2.2 2 1 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain IF4E PF01652.18 EAQ93441.1 - 7.4e-55 185.1 0.2 9.3e-55 184.8 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E AMP-binding PF00501.28 EAQ93442.1 - 2.2e-69 234.1 0.0 1.1e-68 231.8 0.0 1.8 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EAQ93442.1 - 8.1e-11 42.7 0.3 1.6e-10 41.8 0.3 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain BolA PF01722.18 EAQ93443.1 - 5e-30 103.6 2.0 6.1e-30 103.3 2.0 1.1 1 0 0 1 1 1 1 BolA-like protein ASXH PF13919.6 EAQ93443.1 - 0.034 14.2 0.2 0.04 13.9 0.2 1.2 1 0 0 1 1 1 0 Asx homology domain PIP5K PF01504.18 EAQ93445.1 - 4.7e-35 121.2 0.6 3.7e-27 95.2 1.4 2.5 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 EAQ93445.1 - 8.6e-26 90.6 0.0 1.3e-25 90.0 0.0 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.21 EAQ93445.1 - 4.9e-13 49.0 11.8 4.9e-13 49.0 11.8 2.1 2 0 0 2 2 2 1 FYVE zinc finger Peptidase_M3_N PF08439.10 EAQ93446.1 - 0.11 12.7 0.0 0.38 11.0 0.0 2.0 1 0 0 1 1 1 0 Oligopeptidase F Astro_capsid_p PF12226.8 EAQ93446.1 - 0.17 11.0 1.3 0.28 10.3 1.3 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Spt20 PF12090.8 EAQ93447.1 - 1.6e-06 27.9 14.8 3.5e-06 26.8 14.8 1.6 1 0 0 1 1 1 1 Spt20 family DUF2722 PF10846.8 EAQ93447.1 - 2e-05 23.7 11.1 3.3e-05 23.0 11.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) TFIIA PF03153.13 EAQ93447.1 - 0.0013 18.9 16.4 0.0023 18.0 16.4 1.4 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Med15 PF09606.10 EAQ93447.1 - 0.0073 15.1 15.8 0.016 14.0 15.8 1.5 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4175 PF13779.6 EAQ93447.1 - 0.028 12.3 13.5 0.039 11.9 13.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DDHD PF02862.17 EAQ93447.1 - 0.05 13.8 3.3 0.089 12.9 3.3 1.4 1 0 0 1 1 1 0 DDHD domain Roughex PF06020.11 EAQ93447.1 - 0.055 12.6 8.7 0.12 11.5 8.7 1.5 1 0 0 1 1 1 0 Drosophila roughex protein DUF4770 PF15994.5 EAQ93447.1 - 0.056 13.7 5.3 0.11 12.8 5.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) AIF_C PF14721.6 EAQ93447.1 - 0.069 13.5 1.8 0.16 12.3 1.8 1.6 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Presenilin PF01080.17 EAQ93447.1 - 0.071 11.9 7.4 0.1 11.3 7.4 1.2 1 0 0 1 1 1 0 Presenilin eIF-3_zeta PF05091.12 EAQ93447.1 - 0.1 11.6 8.9 0.14 11.1 8.9 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) FAM91_C PF14648.6 EAQ93447.1 - 0.12 11.1 0.5 0.18 10.6 0.5 1.1 1 0 0 1 1 1 0 FAM91 C-terminus Band_3_cyto PF07565.13 EAQ93447.1 - 0.29 10.9 5.8 0.45 10.3 5.8 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain SprA-related PF12118.8 EAQ93447.1 - 0.32 10.1 17.5 0.58 9.2 17.5 1.3 1 0 0 1 1 1 0 SprA-related family SpoIIP PF07454.11 EAQ93447.1 - 0.35 10.3 7.4 0.61 9.5 7.4 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) BRF1 PF07741.13 EAQ93447.1 - 0.55 10.6 8.7 44 4.5 0.0 2.5 2 0 0 2 2 2 0 Brf1-like TBP-binding domain PH_4 PF15404.6 EAQ93447.1 - 0.74 9.6 4.6 1.6 8.5 4.6 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain DUF4834 PF16118.5 EAQ93447.1 - 0.78 10.7 11.3 2.3 9.2 11.3 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) MscS_TM PF12794.7 EAQ93447.1 - 0.84 8.4 2.6 1.4 7.7 2.6 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Hid1 PF12722.7 EAQ93447.1 - 1.9 6.5 5.9 2.5 6.1 5.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CPSF100_C PF13299.6 EAQ93447.1 - 2.1 8.5 8.6 0.99 9.6 5.2 2.0 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal TERB2 PF15101.6 EAQ93447.1 - 2.6 8.1 13.6 7.2 6.6 13.6 1.7 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Neur_chan_memb PF02932.16 EAQ93447.1 - 2.7 8.0 5.0 5.8 6.9 5.0 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region GTA_holin_3TM PF11351.8 EAQ93447.1 - 6.9 7.2 6.8 14 6.3 6.8 1.4 1 0 0 1 1 1 0 Holin of 3TMs, for gene-transfer release Pex14_N PF04695.13 EAQ93447.1 - 7 7.3 22.6 3.5 8.3 15.9 2.6 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Hydin_ADK PF17213.3 EAQ93447.1 - 7.6 6.8 8.4 13 6.0 6.8 2.1 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain Cyclin_N PF00134.23 EAQ93448.1 - 6.8e-40 135.7 1.0 1.3e-39 134.8 0.1 2.0 3 0 0 3 3 3 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EAQ93448.1 - 1.9e-10 40.8 1.4 5.8e-10 39.3 0.0 2.5 2 1 0 2 2 2 1 Cyclin, C-terminal domain Rad4 PF03835.15 EAQ93450.1 - 1.8e-15 56.9 4.3 3.1e-15 56.1 4.3 1.4 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Transglut_core PF01841.19 EAQ93450.1 - 6.2e-15 55.6 2.3 1.5e-14 54.4 2.3 1.7 1 0 0 1 1 1 1 Transglutaminase-like superfamily YdjO PF14169.6 EAQ93450.1 - 0.089 12.5 4.3 1.4 8.7 0.4 2.7 1 1 1 2 2 2 0 Cold-inducible protein YdjO WD40 PF00400.32 EAQ93452.1 - 4.3e-06 27.4 16.9 0.17 12.8 0.0 8.4 10 0 0 10 10 10 2 WD domain, G-beta repeat PQQ_2 PF13360.6 EAQ93452.1 - 1.5e-05 24.7 0.2 5.8e-05 22.8 0.0 1.9 2 1 0 2 2 2 1 PQQ-like domain PQQ PF01011.21 EAQ93452.1 - 0.00024 20.9 0.1 0.03 14.2 0.0 2.8 2 0 0 2 2 2 1 PQQ enzyme repeat ANAPC4_WD40 PF12894.7 EAQ93452.1 - 0.00034 20.8 3.7 1.2 9.4 0.0 6.0 4 2 2 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 EAQ93452.1 - 0.0014 19.0 1.3 8.1 7.1 0.1 4.2 4 0 0 4 4 4 2 PQQ-like domain Ge1_WD40 PF16529.5 EAQ93452.1 - 0.019 14.0 0.0 0.35 9.8 0.0 2.9 4 0 0 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 EAQ93452.1 - 0.024 13.4 0.2 0.43 9.3 0.0 2.6 2 1 1 3 3 3 0 Nup133 N terminal like NAPRTase PF04095.16 EAQ93453.1 - 4.8e-57 193.3 0.4 2e-31 109.5 0.7 2.1 2 0 0 2 2 2 2 Nicotinate phosphoribosyltransferase (NAPRTase) family NAPRTase_N PF17767.1 EAQ93453.1 - 4.5e-35 120.8 0.0 8.1e-35 119.9 0.0 1.4 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain ATP-synt_G PF04718.15 EAQ93456.1 - 3.2e-35 121.0 1.5 1.9e-33 115.3 0.2 2.1 2 0 0 2 2 2 2 Mitochondrial ATP synthase g subunit Collagen_mid PF15984.5 EAQ93456.1 - 0.0057 16.4 2.9 0.0091 15.8 2.8 1.5 1 1 0 1 1 1 1 Bacterial collagen, middle region SipA_VBS PF17985.1 EAQ93456.1 - 0.18 11.8 0.8 10 6.3 0.3 2.4 2 0 0 2 2 2 0 SipA vinculin binding site zf-H2C2_2 PF13465.6 EAQ93457.1 - 0.0063 16.9 0.6 0.018 15.5 0.6 1.8 1 0 0 1 1 1 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 EAQ93457.1 - 0.36 11.8 3.5 4.7 8.3 0.3 3.0 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 EAQ93457.1 - 2 9.0 7.1 1 10.0 0.3 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type ADH_N PF08240.12 EAQ93459.1 - 4.6e-27 94.0 3.4 1e-26 93.0 3.4 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EAQ93459.1 - 6.4e-16 58.5 0.1 1.1e-15 57.8 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EAQ93459.1 - 2.2e-05 24.1 0.6 0.00055 19.5 0.6 2.5 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus Collagen PF01391.18 EAQ93459.1 - 0.13 12.0 1.1 0.23 11.2 1.1 1.4 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) Bap31 PF05529.12 EAQ93461.1 - 7.8e-50 168.2 8.0 1e-49 167.9 8.0 1.1 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 EAQ93461.1 - 7.5e-15 54.7 3.3 7.5e-15 54.7 3.3 2.2 2 0 0 2 2 2 1 Bap31/Bap29 cytoplasmic coiled-coil domain Csm1_N PF18504.1 EAQ93461.1 - 0.037 14.4 0.2 0.037 14.4 0.2 2.0 2 0 0 2 2 2 0 Csm1 N-terminal domain DUF192 PF02643.15 EAQ93461.1 - 0.051 13.7 0.1 0.1 12.8 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized ACR, COG1430 GPS2_interact PF15784.5 EAQ93461.1 - 0.11 13.0 2.0 0.19 12.2 1.6 1.7 1 1 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DivIC PF04977.15 EAQ93461.1 - 2 8.2 7.6 2.9 7.7 0.6 3.3 3 1 1 4 4 4 0 Septum formation initiator DUF4083 PF13314.6 EAQ93461.1 - 4.4 7.3 7.5 45 4.1 1.7 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4083) DUF1479 PF07350.12 EAQ93462.1 - 3.6e-157 523.4 0.0 4.5e-157 523.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) PhyH PF05721.13 EAQ93462.1 - 0.0068 16.7 0.0 0.08 13.2 0.0 2.3 2 0 0 2 2 2 1 Phytanoyl-CoA dioxygenase (PhyH) HHH PF00633.23 EAQ93462.1 - 0.18 11.7 0.1 0.38 10.7 0.1 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif 4F5 PF04419.14 EAQ93463.1 - 0.0019 19.1 6.1 0.0026 18.6 6.1 1.2 1 0 0 1 1 1 1 4F5 protein family DIOX_N PF14226.6 EAQ93464.1 - 7.3e-17 62.2 0.0 8.6e-08 33.0 0.0 3.1 3 0 0 3 3 3 2 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EAQ93464.1 - 1.1e-07 32.2 0.0 2.2e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily WD40 PF00400.32 EAQ93465.1 - 5.3e-06 27.1 15.4 0.023 15.5 0.2 5.9 7 0 0 7 7 7 3 WD domain, G-beta repeat PD40 PF07676.12 EAQ93465.1 - 0.021 14.8 2.4 44 4.2 0.3 4.4 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat ANAPC4_WD40 PF12894.7 EAQ93465.1 - 0.059 13.7 0.3 10 6.5 0.1 4.3 3 2 2 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain MRJP PF03022.16 EAQ93465.1 - 0.18 11.1 1.1 5.4 6.3 0.0 2.8 3 0 0 3 3 3 0 Major royal jelly protein RNA_pol_N PF01194.17 EAQ93466.1 - 1.2e-28 99.2 1.2 1.5e-28 98.8 1.2 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Chordopox_RPO7 PF05864.12 EAQ93466.1 - 0.034 14.4 0.5 0.051 13.8 0.5 1.3 1 0 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) RNA_pol_Rpb1_1 PF04997.12 EAQ93469.1 - 7.2e-108 360.6 0.0 1.3e-107 359.8 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 EAQ93469.1 - 3e-99 331.8 0.2 5.3e-99 331.0 0.2 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 EAQ93469.1 - 1.9e-75 252.6 0.0 5.9e-75 251.1 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 EAQ93469.1 - 1.1e-63 214.5 4.8 2.2e-63 213.6 4.8 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_7 PF04990.12 EAQ93469.1 - 1.9e-46 157.4 7.3 5.7e-46 155.9 7.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_3 PF04983.18 EAQ93469.1 - 4.3e-45 153.5 0.0 1.5e-44 151.7 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 EAQ93469.1 - 5.7e-38 129.2 0.1 1.3e-37 128.0 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.13 EAQ93469.1 - 0.0052 17.1 203.3 0.021 15.2 12.3 14.3 10 4 7 17 17 17 11 RNA polymerase Rpb1 C-terminal repeat zf-C4pol PF14260.6 EAQ93469.1 - 0.11 13.0 1.4 0.3 11.6 1.4 1.7 1 0 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta WD40 PF00400.32 EAQ93470.1 - 1e-15 57.8 5.3 1.9e-05 25.3 0.3 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAQ93470.1 - 1.6e-10 41.1 1.1 0.00063 20.0 0.0 4.8 3 3 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EAQ93470.1 - 7.7e-05 22.6 0.0 0.074 12.9 0.0 3.3 3 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A SRP-alpha_N PF04086.13 EAQ93471.1 - 0.17 11.8 25.5 0.57 10.1 25.5 1.7 1 1 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Presenilin PF01080.17 EAQ93472.1 - 0.19 10.4 2.9 0.38 9.5 2.9 1.4 1 0 0 1 1 1 0 Presenilin Apt1 PF10351.9 EAQ93472.1 - 6.9 5.4 7.6 11 4.7 7.6 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Bromodomain PF00439.25 EAQ93473.1 - 1.3e-34 118.1 0.1 6.1e-16 58.3 0.2 2.4 2 0 0 2 2 2 2 Bromodomain IFT57 PF10498.9 EAQ93473.1 - 0.19 10.7 3.1 0.28 10.1 3.1 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 NOA36 PF06524.12 EAQ93473.1 - 0.84 8.9 11.4 1.4 8.2 11.4 1.2 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.14 EAQ93473.1 - 7.3 4.8 12.4 11 4.2 12.4 1.1 1 0 0 1 1 1 0 CDC45-like protein CKS PF01111.19 EAQ93474.1 - 8.2e-18 64.4 0.1 1.4e-17 63.7 0.1 1.4 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit ERO1 PF04137.15 EAQ93475.1 - 4.5e-121 404.3 0.0 5.8e-121 404.0 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) HVSL PF09749.9 EAQ93476.1 - 9.1e-25 87.5 0.0 1.1e-24 87.3 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein Pal1 PF08316.11 EAQ93477.1 - 9.4e-11 42.6 0.0 2.3e-10 41.4 0.0 1.7 1 0 0 1 1 1 1 Pal1 cell morphology protein CPSF_A PF03178.15 EAQ93478.1 - 9.2e-75 251.9 0.0 2e-74 250.8 0.0 1.5 1 0 0 1 1 1 1 CPSF A subunit region LMBR1 PF04791.16 EAQ93479.1 - 1e-14 54.4 14.7 3.2e-13 49.5 14.7 2.0 1 1 0 1 1 1 1 LMBR1-like membrane protein SR-25 PF10500.9 EAQ93479.1 - 2.1 7.9 11.2 0.14 11.7 5.8 1.7 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein AHH PF14412.6 EAQ93480.1 - 0.18 11.9 0.0 0.32 11.1 0.0 1.4 1 0 0 1 1 1 0 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH UDG PF03167.19 EAQ93482.1 - 6.9e-22 78.1 0.0 1.5e-21 77.0 0.0 1.6 1 1 0 1 1 1 1 Uracil DNA glycosylase superfamily Striatin PF08232.12 EAQ93482.1 - 0.97 10.0 2.5 9.1 6.9 0.1 2.2 2 0 0 2 2 2 0 Striatin family UDPGP PF01704.18 EAQ93483.1 - 1e-54 185.8 0.0 1.4e-54 185.3 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Fer4_20 PF14691.6 EAQ93483.1 - 0.034 13.9 0.1 0.064 13.0 0.1 1.4 1 0 0 1 1 1 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster NTP_transf_3 PF12804.7 EAQ93483.1 - 0.11 12.8 0.0 0.23 11.8 0.0 1.5 1 0 0 1 1 1 0 MobA-like NTP transferase domain Mpv17_PMP22 PF04117.12 EAQ93484.1 - 7.1e-23 80.6 1.2 1.2e-22 79.9 1.2 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family ubiquitin PF00240.23 EAQ93485.1 - 4.2e-18 64.9 0.1 6.4e-18 64.3 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 EAQ93485.1 - 1.1e-06 28.4 0.6 3.9e-06 26.6 0.0 2.3 2 0 0 2 2 2 1 UBA/TS-N domain Rad60-SLD_2 PF13881.6 EAQ93485.1 - 0.005 16.9 0.0 0.0088 16.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EAQ93485.1 - 0.0088 16.6 0.0 0.015 15.9 0.0 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD PF11976.8 EAQ93485.1 - 0.013 15.3 0.3 0.021 14.6 0.3 1.3 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like HOIP-UBA PF16678.5 EAQ93485.1 - 0.082 12.9 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 HOIP UBA domain pair UPF0154 PF03672.13 EAQ93485.1 - 0.089 12.8 1.6 6.7 6.8 0.0 3.6 3 1 0 3 3 3 0 Uncharacterised protein family (UPF0154) Blt1 PF12754.7 EAQ93485.1 - 0.14 12.4 0.1 0.33 11.2 0.1 1.6 1 1 0 1 1 1 0 Blt1 N-terminal domain STI1 PF17830.1 EAQ93485.1 - 5 7.1 8.1 6.9 6.7 2.3 2.7 1 1 1 2 2 2 0 STI1 domain Glyco_hydro_18 PF00704.28 EAQ93486.1 - 5.4e-46 157.8 0.0 1.1e-45 156.8 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Myosin_head PF00063.21 EAQ93487.1 - 7.2e-240 797.8 3.5 8.5e-240 797.6 3.5 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 EAQ93487.1 - 1.5e-46 158.4 0.0 2.6e-46 157.7 0.0 1.4 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding SH3_1 PF00018.28 EAQ93487.1 - 7.1e-13 48.0 0.1 1.5e-12 46.9 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EAQ93487.1 - 4.5e-11 42.4 0.1 1.1e-10 41.2 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EAQ93487.1 - 2.3e-08 33.6 0.0 6.6e-08 32.1 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain IQ PF00612.27 EAQ93487.1 - 0.0049 16.6 10.0 0.17 11.8 2.4 2.7 1 1 1 2 2 2 2 IQ calmodulin-binding motif SH3_3 PF08239.11 EAQ93487.1 - 0.016 15.5 0.4 0.035 14.4 0.4 1.6 1 0 0 1 1 1 0 Bacterial SH3 domain AAA_22 PF13401.6 EAQ93487.1 - 0.043 14.1 0.0 0.12 12.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain Hpr_kinase_C PF07475.12 EAQ93487.1 - 0.052 13.1 0.1 8.3 5.9 0.0 2.3 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain AAA_16 PF13191.6 EAQ93487.1 - 0.088 13.2 0.0 0.26 11.6 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 EAQ93487.1 - 0.15 12.0 0.1 0.37 10.7 0.1 1.6 1 0 0 1 1 1 0 NACHT domain DUF4913 PF16259.5 EAQ93487.1 - 0.16 12.0 1.1 0.42 10.7 1.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4913) FAD_binding_8 PF08022.12 EAQ93488.1 - 1.2e-22 80.0 0.0 2.5e-22 79.0 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 EAQ93488.1 - 4.9e-22 78.7 0.0 8e-22 78.0 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 EAQ93488.1 - 8.5e-20 71.1 10.3 8.5e-20 71.1 10.3 2.4 1 1 1 2 2 2 1 Ferric reductase like transmembrane component LrgA PF03788.14 EAQ93488.1 - 0.021 14.8 0.2 0.021 14.8 0.2 2.1 3 0 0 3 3 3 0 LrgA family NAD_binding_1 PF00175.21 EAQ93488.1 - 0.1 13.3 0.0 2.1 9.0 0.0 2.2 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 EAQ93488.1 - 0.11 12.9 0.0 0.22 11.9 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain DUF4780 PF16012.5 EAQ93488.1 - 0.19 11.1 0.0 0.5 9.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4780) Pex2_Pex12 PF04757.14 EAQ93489.1 - 1.2e-36 126.5 0.0 1.7e-36 125.9 0.0 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.6 EAQ93489.1 - 0.00028 21.0 4.3 0.00059 19.9 4.3 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 EAQ93489.1 - 0.03 14.3 2.6 0.097 12.7 2.6 1.9 1 1 0 1 1 1 0 RING-type zinc-finger DUF501 PF04417.12 EAQ93489.1 - 0.089 12.6 0.3 0.17 11.7 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF501) zf-C3HC4_3 PF13920.6 EAQ93489.1 - 6.4 6.7 9.2 6.9 6.6 4.7 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) IBN_N PF03810.19 EAQ93490.1 - 8.9e-15 54.4 2.0 6.4e-14 51.6 0.3 3.3 4 0 0 4 4 4 1 Importin-beta N-terminal domain Xpo1 PF08389.12 EAQ93490.1 - 7.8e-05 22.8 3.4 0.00031 20.8 0.1 3.4 5 0 0 5 5 5 1 Exportin 1-like protein TPR_10 PF13374.6 EAQ93491.1 - 5e-70 229.7 0.1 8.9e-12 44.5 0.1 6.7 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_12 PF13424.6 EAQ93491.1 - 1.2e-55 185.7 3.7 8.6e-14 51.6 0.0 6.3 1 1 5 6 6 6 6 Tetratricopeptide repeat TPR_7 PF13176.6 EAQ93491.1 - 1.1e-19 68.9 1.7 0.00062 19.6 0.0 6.4 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_16 PF13432.6 EAQ93491.1 - 2e-13 50.7 0.0 0.07 13.8 0.0 6.1 5 1 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 EAQ93491.1 - 2.9e-11 42.6 1.9 0.65 10.2 0.0 6.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_4 PF07721.14 EAQ93491.1 - 5.2e-11 42.1 0.2 8.6 7.3 0.0 6.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.28 EAQ93491.1 - 6.2e-09 35.3 0.0 0.63 10.0 0.0 5.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_MalT PF17874.1 EAQ93491.1 - 1.4e-08 34.5 9.2 3.1e-06 26.8 2.3 2.3 1 1 1 2 2 2 2 MalT-like TPR region TPR_19 PF14559.6 EAQ93491.1 - 2.8e-08 34.1 0.4 0.11 13.0 0.0 5.2 3 1 2 5 5 5 3 Tetratricopeptide repeat NB-ARC PF00931.22 EAQ93491.1 - 1.7e-07 30.7 0.0 4.3e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain TPR_14 PF13428.6 EAQ93491.1 - 1.8e-06 28.3 4.6 42 5.3 0.0 6.9 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_17 PF13431.6 EAQ93491.1 - 2.2e-06 27.6 0.6 0.53 10.8 0.0 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 EAQ93491.1 - 4.6e-05 23.3 1.0 11 6.6 0.0 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat Ses_B PF17046.5 EAQ93491.1 - 0.00038 20.3 1.1 0.0009 19.1 1.1 1.7 1 0 0 1 1 1 1 SesB domain on fungal death-pathway protein NACHT PF05729.12 EAQ93491.1 - 0.00057 19.8 0.0 0.001 19.0 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_25 PF13481.6 EAQ93491.1 - 0.0022 17.6 0.0 0.0041 16.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain TPR_5 PF12688.7 EAQ93491.1 - 0.0036 17.5 0.0 17 5.7 0.0 3.6 1 1 2 3 3 3 0 Tetratrico peptide repeat PPR PF01535.20 EAQ93491.1 - 0.031 14.5 0.7 69 4.0 0.1 4.6 5 0 0 5 5 4 0 PPR repeat AAA_16 PF13191.6 EAQ93491.1 - 0.11 12.9 0.1 0.4 11.1 0.1 2.1 1 1 0 1 1 1 0 AAA ATPase domain HemY_N PF07219.13 EAQ93491.1 - 0.2 11.8 5.5 34 4.7 0.0 4.7 1 1 3 5 5 5 0 HemY protein N-terminus TPR_6 PF13174.6 EAQ93491.1 - 0.43 11.3 1.9 86 4.1 0.1 4.8 5 0 0 5 5 4 0 Tetratricopeptide repeat Cytochrom_B558a PF05038.13 EAQ93493.1 - 0.00054 19.6 0.2 0.0024 17.5 0.1 2.0 1 1 0 2 2 2 1 Cytochrome Cytochrome b558 alpha-subunit Pribosyltran PF00156.27 EAQ93496.1 - 8.4e-14 51.4 0.0 1.9e-13 50.2 0.0 1.5 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EAQ93496.1 - 0.017 14.5 0.0 0.028 13.8 0.0 1.3 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Glyco_hydro_47 PF01532.20 EAQ93497.1 - 2.9e-111 372.6 0.0 3.6e-111 372.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Radical_SAM_C PF16199.5 EAQ93500.1 - 1.8e-32 111.2 0.0 2.8e-32 110.6 0.0 1.3 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Acetyltransf_1 PF00583.25 EAQ93500.1 - 1.5e-09 38.1 0.1 2.2e-09 37.6 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EAQ93500.1 - 3.4e-06 27.0 0.0 6.3e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EAQ93500.1 - 0.01 16.3 0.0 0.018 15.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Fungal_trans PF04082.18 EAQ93502.1 - 0.00023 20.3 0.2 0.00062 18.9 0.2 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cytochrom_B562 PF07361.11 EAQ93502.1 - 0.048 14.3 0.3 0.13 13.0 0.2 1.7 2 0 0 2 2 2 0 Cytochrome b562 Zn_clus PF00172.18 EAQ93502.1 - 0.081 13.1 1.8 0.18 11.9 1.8 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain PEP-utilisers_N PF05524.13 EAQ93502.1 - 0.1 12.8 0.1 1.3 9.2 0.1 2.2 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal Nup54 PF13874.6 EAQ93502.1 - 0.16 12.0 4.7 0.047 13.8 0.9 2.0 3 0 0 3 3 3 0 Nucleoporin complex subunit 54 PRCC PF10253.9 EAQ93503.1 - 0.022 15.5 3.2 0.03 15.1 3.2 1.1 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting adh_short_C2 PF13561.6 EAQ93504.1 - 3.1e-54 184.0 2.0 4.4e-54 183.5 2.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EAQ93504.1 - 6e-45 153.1 1.3 7.6e-45 152.8 1.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EAQ93504.1 - 3.9e-13 49.7 1.4 3.9e-13 49.7 1.4 1.6 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 EAQ93504.1 - 0.0005 19.6 0.5 0.00098 18.6 0.5 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EAQ93504.1 - 0.0035 16.8 0.1 0.0075 15.7 0.0 1.6 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase TetR_C_27 PF17935.1 EAQ93506.1 - 0.0065 16.5 0.1 0.29 11.2 0.0 2.4 2 0 0 2 2 2 2 Tetracyclin repressor-like, C-terminal domain Globin PF00042.22 EAQ93507.1 - 1.5e-10 41.6 0.0 2.5e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Globin NAD_binding_1 PF00175.21 EAQ93507.1 - 2.1e-06 28.4 0.0 5.8e-06 26.9 0.0 1.8 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 EAQ93507.1 - 0.00013 22.2 0.0 0.00022 21.5 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Protoglobin PF11563.8 EAQ93507.1 - 0.00037 20.4 0.0 0.00054 19.9 0.0 1.3 1 0 0 1 1 1 1 Protoglobin Fib_alpha PF08702.10 EAQ93507.1 - 0.046 13.9 0.2 0.077 13.2 0.2 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family NAD_binding_6 PF08030.12 EAQ93507.1 - 0.07 13.2 0.9 0.47 10.6 0.1 2.2 2 0 0 2 2 2 0 Ferric reductase NAD binding domain Glyco_hydro_85 PF03644.13 EAQ93507.1 - 0.13 11.7 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 85 SpoVIF PF14069.6 EAQ93508.1 - 0.09 12.6 0.1 0.19 11.5 0.1 1.5 1 0 0 1 1 1 0 Stage VI sporulation protein F Bud13 PF09736.9 EAQ93511.1 - 0.035 14.5 3.9 0.079 13.3 3.9 1.6 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex Iron_traffic PF04362.14 EAQ93511.1 - 0.068 12.9 0.0 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 Bacterial Fe(2+) trafficking Cwf_Cwc_15 PF04889.12 EAQ93511.1 - 0.08 12.7 12.5 0.22 11.2 12.5 1.7 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Asp-B-Hydro_N PF05279.11 EAQ93511.1 - 0.093 12.8 7.5 0.16 12.1 7.5 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region EF-hand_1 PF00036.32 EAQ93511.1 - 1.1 9.0 4.9 7.7 6.3 1.7 2.7 2 0 0 2 2 2 0 EF hand Vps53_N PF04100.12 EAQ93512.1 - 2.9e-76 256.9 0.9 3.1e-74 250.2 1.0 2.1 1 1 0 1 1 1 1 Vps53-like, N-terminal HAUS5 PF14817.6 EAQ93512.1 - 0.0011 17.8 1.0 0.0015 17.4 0.3 1.5 2 0 0 2 2 2 1 HAUS augmin-like complex subunit 5 Spc7 PF08317.11 EAQ93512.1 - 0.046 12.6 1.6 0.078 11.8 1.6 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein FliG_N PF14842.6 EAQ93512.1 - 0.075 13.6 0.0 0.24 11.9 0.0 1.8 1 0 0 1 1 1 0 FliG N-terminal domain APG6_N PF17675.1 EAQ93512.1 - 0.86 10.1 3.8 0.84 10.2 0.8 2.5 2 1 0 2 2 2 0 Apg6 coiled-coil region NPR2 PF06218.11 EAQ93513.1 - 3e-90 303.1 0.0 2.3e-89 300.2 0.0 1.9 1 1 0 1 1 1 1 Nitrogen permease regulator 2 tRNA-synt_1b PF00579.25 EAQ93514.1 - 1.2e-77 261.2 0.0 1.8e-77 260.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) TyrRSs_C PF16714.5 EAQ93514.1 - 1.9e-47 160.0 0.0 4.3e-47 158.9 0.0 1.6 1 0 0 1 1 1 1 Tyrosyl-tRNA synthetase C-terminal domain CybS PF05328.12 EAQ93515.1 - 6.4e-53 178.0 0.0 8e-53 177.7 0.0 1.1 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit Sdh_cyt PF01127.22 EAQ93515.1 - 0.024 14.7 0.3 0.12 12.4 0.3 1.9 1 1 0 1 1 1 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Zn_clus PF00172.18 EAQ93516.1 - 8.7e-06 25.8 11.6 1.4e-05 25.1 11.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EAQ93516.1 - 3e-05 23.2 0.1 4.8e-05 22.5 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3419 PF11899.8 EAQ93517.1 - 4.6e-153 510.0 0.0 5.9e-153 509.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_23 PF13489.6 EAQ93517.1 - 2.7e-07 30.6 0.0 2.7e-06 27.3 0.0 2.2 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAQ93517.1 - 4.6e-07 30.4 0.0 2e-05 25.2 0.0 3.3 4 0 0 4 4 4 1 Methyltransferase domain Methyltransf_12 PF08242.12 EAQ93517.1 - 1.1e-06 29.2 0.0 8.5e-06 26.4 0.0 2.4 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAQ93517.1 - 1.5e-05 24.8 0.0 6.1e-05 22.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EAQ93517.1 - 1.9e-05 25.2 0.0 0.00098 19.7 0.0 3.3 4 0 0 4 4 4 1 Methyltransferase domain Ubie_methyltran PF01209.18 EAQ93517.1 - 5.7e-05 22.6 0.0 0.12 11.7 0.0 2.5 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family PCMT PF01135.19 EAQ93517.1 - 0.019 14.7 0.0 0.036 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ada3 PF10198.9 EAQ93518.1 - 4.2e-55 185.5 0.0 4.2e-55 185.5 0.0 2.5 3 1 0 3 3 3 1 Histone acetyltransferases subunit 3 Med3 PF11593.8 EAQ93518.1 - 0.069 12.3 6.1 0.33 10.1 2.2 2.4 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal zf-RING_2 PF13639.6 EAQ93519.1 - 6.8e-11 42.3 7.3 1.4e-10 41.4 7.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EAQ93519.1 - 5e-09 35.9 5.5 9.5e-09 35.0 5.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EAQ93519.1 - 4e-08 32.9 3.0 4e-08 32.9 3.0 2.0 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_5 PF14634.6 EAQ93519.1 - 8.4e-07 28.9 5.2 1.3e-06 28.2 5.2 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 EAQ93519.1 - 7.2e-06 26.2 4.3 1.4e-05 25.3 3.3 2.0 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EAQ93519.1 - 1.4e-05 24.8 6.7 2.4e-05 24.1 6.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EAQ93519.1 - 2e-05 24.5 2.3 2e-05 24.5 2.3 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EAQ93519.1 - 0.00083 19.2 4.5 0.0013 18.5 4.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EAQ93519.1 - 0.0024 17.7 5.7 0.0044 16.9 5.7 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 EAQ93519.1 - 0.0027 17.7 0.8 0.0073 16.3 0.8 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 EAQ93519.1 - 0.065 12.9 2.6 0.12 12.0 2.6 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 EAQ93519.1 - 0.11 12.7 6.9 0.23 11.6 6.9 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 EAQ93519.1 - 0.17 11.7 3.6 0.29 11.0 3.6 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-HC5HC2H_2 PF13832.6 EAQ93519.1 - 0.2 11.8 0.5 0.38 10.9 0.4 1.5 1 1 0 1 1 1 0 PHD-zinc-finger like domain YdjO PF14169.6 EAQ93519.1 - 0.27 11.0 1.6 9 6.1 0.1 3.0 2 1 1 3 3 3 0 Cold-inducible protein YdjO FANCL_C PF11793.8 EAQ93519.1 - 0.38 11.0 4.2 3.8 7.7 4.1 2.2 1 1 1 2 2 2 0 FANCL C-terminal domain PHD PF00628.29 EAQ93519.1 - 0.74 9.7 3.5 1.3 9.0 3.5 1.4 1 0 0 1 1 1 0 PHD-finger DUF1272 PF06906.11 EAQ93519.1 - 4.2 7.5 5.2 11 6.2 0.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1272) DUF726 PF05277.12 EAQ93520.1 - 1.2e-120 402.5 0.8 1.7e-120 402.1 0.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Thioesterase PF00975.20 EAQ93520.1 - 4.7e-05 23.6 0.0 0.00011 22.3 0.0 1.6 1 0 0 1 1 1 1 Thioesterase domain Osteopontin PF00865.18 EAQ93520.1 - 2.7 7.4 7.5 6.1 6.2 7.5 1.5 1 0 0 1 1 1 0 Osteopontin Noc2 PF03715.13 EAQ93521.1 - 4.4e-117 390.6 0.0 9.2e-117 389.6 0.0 1.5 1 0 0 1 1 1 1 Noc2p family Nop14 PF04147.12 EAQ93521.1 - 1e-05 24.0 0.1 1e-05 24.0 0.1 3.8 2 2 1 3 3 3 1 Nop14-like family SWIRM-assoc_2 PF16496.5 EAQ93523.1 - 0.00072 18.5 0.3 0.00072 18.5 0.3 4.5 4 1 1 5 5 5 1 SWIRM-associated domain at the N-terminal AT_hook PF02178.19 EAQ93523.1 - 0.0048 16.6 12.0 0.31 11.0 0.4 4.7 4 0 0 4 4 4 2 AT hook motif PTCB-BRCT PF12738.7 EAQ93523.1 - 0.017 15.0 0.0 4.1 7.4 0.0 2.4 2 0 0 2 2 2 0 twin BRCT domain DUF155 PF02582.14 EAQ93524.1 - 4.7e-54 183.1 0.1 7.2e-54 182.5 0.1 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 LBP_BPI_CETP_C PF02886.17 EAQ93524.1 - 0.16 11.4 0.1 0.25 10.8 0.1 1.2 1 0 0 1 1 1 0 LBP / BPI / CETP family, C-terminal domain zinc_ribbon_15 PF17032.5 EAQ93525.1 - 1.5e-05 25.7 0.7 2.1e-05 25.2 0.7 1.2 1 0 0 1 1 1 1 zinc-ribbon family ArsA_ATPase PF02374.15 EAQ93526.1 - 3.6e-24 85.5 0.1 5.2e-24 85.0 0.1 1.2 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.23 EAQ93526.1 - 1.1e-10 41.7 0.3 1.8e-10 40.9 0.1 1.6 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain RNase_P_p30 PF01876.16 EAQ93526.1 - 1.4e-10 41.1 0.0 1.1e-08 34.9 0.0 2.3 2 0 0 2 2 2 1 RNase P subunit p30 AAA_31 PF13614.6 EAQ93526.1 - 9.2e-10 38.7 0.0 1.8e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain Fer4_NifH PF00142.18 EAQ93526.1 - 9.6e-06 25.2 0.0 1.6e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ParA PF10609.9 EAQ93526.1 - 0.00016 21.2 0.1 0.00025 20.6 0.1 1.2 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CBP_BcsQ PF06564.12 EAQ93526.1 - 0.00095 18.7 0.0 0.0015 18.1 0.0 1.2 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsQ SRP54 PF00448.22 EAQ93526.1 - 0.0011 18.7 0.0 0.0019 17.9 0.0 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_25 PF13481.6 EAQ93526.1 - 0.14 11.7 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 EAQ93526.1 - 0.15 11.2 0.0 0.25 10.5 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain GFA PF04828.14 EAQ93528.1 - 3.5e-06 27.2 1.1 3.5e-06 27.2 1.1 1.6 2 1 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme HET PF06985.11 EAQ93529.1 - 9.3e-33 113.6 0.0 1.6e-32 112.8 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Acyl_transf_3 PF01757.22 EAQ93530.1 - 1.1e-30 106.9 13.6 1.8e-30 106.2 13.6 1.4 1 1 0 1 1 1 1 Acyltransferase family PepSY_TM PF03929.16 EAQ93531.1 - 0.0021 17.8 0.1 0.0025 17.5 0.1 1.0 1 0 0 1 1 1 1 PepSY-associated TM region LapA_dom PF06305.11 EAQ93531.1 - 0.0064 16.3 3.8 0.02 14.7 0.1 2.1 2 0 0 2 2 2 1 Lipopolysaccharide assembly protein A domain Ctr PF04145.15 EAQ93531.1 - 0.21 12.2 0.3 0.23 12.1 0.3 1.0 1 0 0 1 1 1 0 Ctr copper transporter family Med8 PF10232.9 EAQ93533.1 - 1.2e-36 126.5 0.1 1.4e-36 126.2 0.1 1.1 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 FlgN PF05130.12 EAQ93533.1 - 0.023 15.2 0.4 0.023 15.2 0.4 2.1 2 0 0 2 2 2 0 FlgN protein Nop53 PF07767.11 EAQ93533.1 - 0.19 11.1 6.3 0.29 10.5 6.3 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Pes-10 PF07149.11 EAQ93533.1 - 0.2 10.7 3.2 0.56 9.2 3.2 1.6 1 1 0 1 1 1 0 Pes-10 PBP1_TM PF14812.6 EAQ93533.1 - 0.55 10.6 11.8 3.8 8.0 3.5 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FlxA PF14282.6 EAQ93533.1 - 0.57 10.2 0.1 0.57 10.2 0.1 2.4 2 1 0 2 2 2 0 FlxA-like protein BUD22 PF09073.10 EAQ93533.1 - 0.92 8.8 8.8 1.2 8.4 8.8 1.1 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 EAQ93533.1 - 1.3 7.1 13.6 2 6.6 13.6 1.1 1 0 0 1 1 1 0 Nop14-like family CENP-B_dimeris PF09026.10 EAQ93533.1 - 1.5 9.3 15.5 1.6 9.1 8.2 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Nucleo_P87 PF07267.11 EAQ93533.1 - 1.6 7.5 5.5 2.4 6.9 5.5 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 GRP PF07172.11 EAQ93533.1 - 5 7.9 8.3 0.94 10.2 3.1 2.0 2 0 0 2 2 2 0 Glycine rich protein family Sulfatase PF00884.23 EAQ93534.1 - 1.3e-52 179.1 0.0 1.7e-52 178.7 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Choline_sulf_C PF12411.8 EAQ93534.1 - 8.7e-29 99.1 1.8 4.3e-28 96.9 0.8 2.4 2 0 0 2 2 2 1 Choline sulfatase enzyme C terminal Phosphodiest PF01663.22 EAQ93534.1 - 3.5e-09 36.7 0.1 0.001 18.8 0.0 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4976 PF16347.5 EAQ93534.1 - 0.0024 18.1 0.0 0.0051 17.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4976) PQ-loop PF04193.14 EAQ93535.1 - 9.4e-24 83.0 4.7 2.6e-13 49.5 2.8 2.6 2 0 0 2 2 2 2 PQ loop repeat MtrF PF09472.10 EAQ93535.1 - 0.069 12.6 2.3 2.3 7.7 0.1 2.4 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) Ric8 PF10165.9 EAQ93536.1 - 4.9e-133 444.5 0.0 6.3e-133 444.2 0.0 1.1 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn Chromo PF00385.24 EAQ93536.1 - 8.1e-14 51.3 0.1 1.5e-13 50.4 0.1 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Baculo_PP31 PF05311.11 EAQ93536.1 - 1.7 8.1 5.6 0.16 11.4 0.9 1.6 2 0 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) Rif1_N PF12231.8 EAQ93537.1 - 1.1e-149 498.5 1.5 1.6e-149 498.0 1.5 1.2 1 0 0 1 1 1 1 Rap1-interacting factor 1 N terminal Aldose_epim PF01263.20 EAQ93538.1 - 7.2e-23 81.3 0.0 9.6e-23 80.9 0.0 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase DAHP_synth_2 PF01474.16 EAQ93539.1 - 2.7e-202 672.1 0.0 3e-202 671.9 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family UBA_4 PF14555.6 EAQ93540.1 - 0.11 12.3 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 UBA-like domain tRNA_anti-like PF12869.7 EAQ93540.1 - 0.46 10.1 3.1 0.99 9.0 3.1 1.7 1 1 0 1 1 1 0 tRNA_anti-like E1-E2_ATPase PF00122.20 EAQ93541.1 - 4.8e-50 169.6 0.4 4.8e-50 169.6 0.4 1.9 2 0 0 2 2 2 1 E1-E2 ATPase HMA PF00403.26 EAQ93541.1 - 4.4e-46 155.2 1.4 4.7e-12 46.2 0.1 4.5 4 0 0 4 4 4 4 Heavy-metal-associated domain Hydrolase PF00702.26 EAQ93541.1 - 3.6e-39 135.2 2.4 3.6e-39 135.2 2.4 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EAQ93541.1 - 0.00016 21.5 2.4 0.00033 20.5 1.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase zinc_ribbon_12 PF11331.8 EAQ93541.1 - 0.048 13.5 0.8 19 5.1 0.0 3.3 3 0 0 3 3 3 0 Probable zinc-ribbon domain DUF1656 PF07869.12 EAQ93541.1 - 2.5 8.2 7.9 2.9 8.0 5.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1656) PCI PF01399.27 EAQ93542.1 - 0.00064 20.2 0.0 0.0011 19.5 0.0 1.4 1 0 0 1 1 1 1 PCI domain RGS PF00615.19 EAQ93543.1 - 1.9e-09 37.8 0.0 1e-07 32.3 0.0 2.2 1 1 0 1 1 1 1 Regulator of G protein signaling domain Ribosomal_L31e PF01198.19 EAQ93544.1 - 5.8e-39 132.2 0.6 7.8e-39 131.8 0.6 1.2 1 0 0 1 1 1 1 Ribosomal protein L31e UQ_con PF00179.26 EAQ93545.1 - 6.7e-49 165.1 0.0 7.9e-49 164.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EAQ93545.1 - 7.8e-06 25.6 0.0 1e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 EAQ93545.1 - 0.0016 18.8 0.0 0.0017 18.6 0.0 1.3 1 0 0 1 1 1 1 RWD domain UEV PF05743.13 EAQ93545.1 - 0.0071 16.2 0.0 0.011 15.6 0.0 1.4 1 1 0 1 1 1 1 UEV domain Pkinase PF00069.25 EAQ93546.1 - 4.3e-53 180.4 0.0 5.8e-53 179.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ93546.1 - 2.4e-24 86.0 0.0 3.5e-24 85.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAQ93546.1 - 1.6e-07 30.9 0.0 2.3e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EAQ93546.1 - 0.0076 15.6 0.0 0.019 14.3 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EAQ93546.1 - 0.013 15.4 4.0 0.82 9.5 0.0 3.3 3 1 0 3 3 3 0 Phosphotransferase enzyme family SprT-like PF10263.9 EAQ93547.1 - 0.0012 18.7 0.0 0.0019 18.0 0.0 1.2 1 0 0 1 1 1 1 SprT-like family F-box-like PF12937.7 EAQ93548.1 - 3.9e-09 36.3 0.2 8.5e-09 35.2 0.0 1.7 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EAQ93548.1 - 2.5e-07 30.4 0.0 6.9e-07 29.0 0.0 1.8 1 0 0 1 1 1 1 F-box domain ABC_tran PF00005.27 EAQ93550.1 - 8.5e-49 165.6 0.0 2e-28 99.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EAQ93550.1 - 3.7e-36 125.2 23.5 8.3e-24 84.7 9.7 3.3 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 EAQ93550.1 - 1.5e-09 37.7 0.0 0.00051 19.6 0.0 4.1 3 1 1 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EAQ93550.1 - 0.00022 21.6 0.5 0.043 14.2 0.1 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 EAQ93550.1 - 0.002 17.8 1.0 2.5 7.9 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain T2SSE PF00437.20 EAQ93550.1 - 0.0024 17.0 0.0 0.53 9.3 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein MMR_HSR1 PF01926.23 EAQ93550.1 - 0.0029 17.7 0.3 0.1 12.7 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EAQ93550.1 - 0.0047 16.9 0.1 2.3 8.1 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 EAQ93550.1 - 0.0049 16.5 0.0 1.3 8.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EAQ93550.1 - 0.011 16.0 0.3 7.9 6.8 0.0 3.1 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.17 EAQ93550.1 - 0.016 15.3 2.3 0.59 10.2 0.1 2.6 2 0 0 2 2 2 0 Helicase HerA, central domain IstB_IS21 PF01695.17 EAQ93550.1 - 0.02 14.7 0.0 1.7 8.4 0.0 2.7 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_30 PF13604.6 EAQ93550.1 - 0.056 13.2 0.5 3.6 7.3 0.1 2.9 3 0 0 3 3 3 0 AAA domain DUF2075 PF09848.9 EAQ93550.1 - 0.074 12.3 0.3 1.1 8.4 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) SbcCD_C PF13558.6 EAQ93550.1 - 0.096 12.9 0.0 19 5.5 0.0 3.3 3 0 0 3 3 3 0 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 EAQ93550.1 - 0.098 13.1 4.4 0.8 10.2 0.2 2.7 3 0 0 3 3 2 0 AAA domain AAA_21 PF13304.6 EAQ93550.1 - 0.12 12.2 0.2 17 5.1 0.0 3.5 4 0 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 EAQ93550.1 - 0.18 11.5 0.2 3 7.5 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain AAA_7 PF12775.7 EAQ93550.1 - 0.22 11.0 0.2 23 4.4 0.1 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region CbiA PF01656.23 EAQ93550.1 - 0.23 11.5 1.5 30 4.7 0.7 2.9 3 0 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain WD40 PF00400.32 EAQ93551.1 - 2e-15 56.9 9.8 0.0084 17.0 0.1 7.1 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAQ93551.1 - 1.2e-14 54.3 0.0 0.002 18.4 0.0 5.4 4 2 2 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EAQ93551.1 - 0.0006 19.7 0.1 0.18 11.7 0.0 3.0 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.14 EAQ93551.1 - 0.0062 15.6 0.0 0.57 9.2 0.0 2.6 2 1 1 3 3 3 1 Coatomer WD associated region HIRA_B PF09453.10 EAQ93551.1 - 0.018 14.9 0.5 0.018 14.9 0.5 2.5 3 0 0 3 3 3 0 HIRA B motif PD40 PF07676.12 EAQ93551.1 - 2.3 8.3 4.6 7.1 6.7 0.4 3.5 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Amidase PF01425.21 EAQ93552.1 - 5.5e-80 269.5 0.0 8.3e-80 268.9 0.0 1.3 1 1 0 1 1 1 1 Amidase Methyltransf_11 PF08241.12 EAQ93553.1 - 0.0051 17.4 0.2 0.031 14.9 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAQ93553.1 - 0.028 15.1 0.4 1.6 9.5 0.0 2.9 2 1 1 3 3 3 0 Methyltransferase domain PCMT PF01135.19 EAQ93553.1 - 0.22 11.2 0.0 0.87 9.3 0.0 1.8 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF1776 PF08643.10 EAQ93554.1 - 1.2e-114 382.7 0.0 1.5e-114 382.4 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) adh_short PF00106.25 EAQ93554.1 - 0.01 15.3 0.0 0.02 14.4 0.0 1.5 1 1 0 1 1 1 0 short chain dehydrogenase Pyr_redox_2 PF07992.14 EAQ93555.1 - 5.8e-32 111.1 0.9 6e-30 104.5 0.0 2.6 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase ADH_zinc_N PF00107.26 EAQ93555.1 - 5.9e-31 107.1 1.5 2.1e-30 105.3 0.9 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Pyr_redox PF00070.27 EAQ93555.1 - 5.9e-13 49.2 0.2 1.6e-10 41.4 0.1 2.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EAQ93555.1 - 2.5e-12 46.7 0.0 1.2e-10 41.1 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ADH_zinc_N_2 PF13602.6 EAQ93555.1 - 3.2e-06 28.2 0.1 1.3e-05 26.2 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase NAD_binding_7 PF13241.6 EAQ93555.1 - 2.9e-05 24.4 0.1 0.01 16.3 0.0 2.9 2 1 0 2 2 2 1 Putative NAD(P)-binding ADH_N PF08240.12 EAQ93555.1 - 3.2e-05 23.8 0.0 0.00011 22.0 0.0 2.0 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Thi4 PF01946.17 EAQ93555.1 - 0.00015 21.1 0.1 0.00078 18.8 0.0 2.2 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 EAQ93555.1 - 0.0004 20.5 1.9 0.15 12.3 0.0 3.2 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 EAQ93555.1 - 0.0016 17.8 6.6 0.084 12.2 0.9 3.3 3 0 0 3 3 3 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 EAQ93555.1 - 0.0024 17.0 7.2 0.9 8.6 0.3 3.9 2 2 2 4 4 4 2 Glucose inhibited division protein A FAD_oxidored PF12831.7 EAQ93555.1 - 0.02 14.2 0.1 0.044 13.1 0.1 1.6 1 0 0 1 1 1 0 FAD dependent oxidoreductase K_oxygenase PF13434.6 EAQ93555.1 - 0.026 13.7 0.1 0.89 8.6 0.0 2.6 3 0 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 EAQ93555.1 - 0.027 14.1 2.0 12 5.3 0.3 3.3 2 1 1 3 3 3 0 FAD dependent oxidoreductase adh_short PF00106.25 EAQ93555.1 - 0.033 13.6 0.4 0.33 10.4 0.1 2.2 2 0 0 2 2 2 0 short chain dehydrogenase FAD_binding_3 PF01494.19 EAQ93555.1 - 0.033 13.4 0.1 5.4 6.1 0.0 2.3 2 0 0 2 2 2 0 FAD binding domain ADH_N_2 PF16884.5 EAQ93555.1 - 0.036 14.0 0.0 0.17 11.8 0.0 2.1 2 0 0 2 2 2 0 N-terminal domain of oxidoreductase Trp_halogenase PF04820.14 EAQ93555.1 - 0.063 12.1 0.4 0.72 8.6 0.0 2.5 3 0 0 3 3 3 0 Tryptophan halogenase TrkA_N PF02254.18 EAQ93555.1 - 0.08 13.2 4.0 0.15 12.4 0.1 3.0 4 0 0 4 4 4 0 TrkA-N domain HI0933_like PF03486.14 EAQ93555.1 - 0.083 11.6 3.9 2.7 6.6 0.1 4.1 3 2 2 5 5 5 0 HI0933-like protein 2-Hacid_dh_C PF02826.19 EAQ93555.1 - 0.17 11.3 2.1 1.7 8.0 0.2 2.5 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 EAQ93555.1 - 0.17 12.0 0.1 17 5.4 0.0 3.1 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.24 EAQ93555.1 - 0.89 8.6 10.4 0.13 11.3 0.3 3.8 4 1 1 5 5 5 0 FAD binding domain DUF1772 PF08592.11 EAQ93556.1 - 1.3e-11 45.0 0.8 2e-11 44.4 0.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) MFS_1 PF07690.16 EAQ93557.1 - 7.7e-19 67.8 34.1 4.2e-13 48.9 10.9 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EAQ93557.1 - 1.3e-16 60.5 19.5 1.4e-14 53.9 1.9 2.7 2 1 1 3 3 3 2 Sugar (and other) transporter DUF1345 PF07077.11 EAQ93557.1 - 0.013 15.2 1.9 0.26 11.0 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1345) UPF0242 PF06785.11 EAQ93559.1 - 0.067 13.3 14.3 0.61 10.2 6.7 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Ntox28 PF15605.6 EAQ93559.1 - 0.69 10.2 8.6 0.48 10.7 4.1 2.8 1 1 0 2 2 2 0 Bacterial toxin 28 DUF3453 PF11935.8 EAQ93560.1 - 2e-69 233.7 0.2 4.8e-69 232.4 0.1 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3453) Ribosomal_60s PF00428.19 EAQ93560.1 - 0.67 10.6 3.2 1 10.0 0.5 2.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein Sds3 PF08598.11 EAQ93562.1 - 2.4e-16 60.4 1.7 2.4e-16 60.4 1.7 2.9 2 1 0 2 2 2 1 Sds3-like DUF2315 PF10231.9 EAQ93562.1 - 2.5 8.2 5.3 18 5.5 1.8 2.8 2 1 0 2 2 2 0 Apoptogenic protein 1 RRM_1 PF00076.22 EAQ93563.1 - 2.4e-10 40.1 0.1 2.6e-07 30.4 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Tubulin_C PF03953.17 EAQ93564.1 - 0.00024 21.3 0.0 0.00036 20.7 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Glyco_hydro_16 PF00722.21 EAQ93565.1 - 1.1e-16 60.8 0.6 1.6e-16 60.3 0.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.15 EAQ93565.1 - 3.9e-05 22.2 1.9 0.044 12.2 0.0 2.3 3 0 0 3 3 3 2 Beta-glucan synthesis-associated protein (SKN1) Zn_clus PF00172.18 EAQ93566.1 - 1.6e-06 28.1 9.1 4.5e-06 26.7 9.1 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GPI-anchored PF10342.9 EAQ93567.1 - 1.7e-20 73.5 0.0 1.7e-20 73.5 0.0 2.9 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Apt1 PF10351.9 EAQ93567.1 - 0.16 10.8 2.8 0.2 10.5 2.8 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain zf-CCCH PF00642.24 EAQ93572.1 - 0.00021 21.1 7.2 0.00039 20.2 7.2 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 EAQ93572.1 - 0.0014 19.3 1.9 0.0014 19.3 1.9 2.5 2 1 0 2 2 2 1 Torus domain zf_CCCH_4 PF18345.1 EAQ93572.1 - 0.11 12.5 11.6 0.18 11.9 11.6 1.3 1 0 0 1 1 1 0 Zinc finger domain zf-CCCH_4 PF18044.1 EAQ93572.1 - 0.98 9.3 11.4 1.6 8.6 11.4 1.4 1 0 0 1 1 1 0 CCCH-type zinc finger Velvet PF11754.8 EAQ93572.1 - 1.9 8.3 16.6 1.4 8.8 7.3 2.2 2 0 0 2 2 2 0 Velvet factor BORG_CEP PF14957.6 EAQ93572.1 - 3.7 8.7 12.6 0.45 11.7 2.8 2.3 2 0 0 2 2 2 0 Cdc42 effector TFIIA PF03153.13 EAQ93572.1 - 6.2 6.7 35.1 13 5.7 35.3 1.5 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CAP_GLY PF01302.25 EAQ93573.1 - 4.2e-20 71.5 0.1 1.1e-19 70.2 0.1 1.7 2 0 0 2 2 2 1 CAP-Gly domain LRR_4 PF12799.7 EAQ93573.1 - 9.8e-15 54.4 1.9 3.2e-05 24.2 0.1 4.4 4 0 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EAQ93573.1 - 6.3e-09 35.5 6.7 0.022 14.5 2.2 5.2 2 1 4 6 6 6 3 Leucine rich repeat LRR_6 PF13516.6 EAQ93573.1 - 6.4e-08 32.0 1.0 1.5 9.0 0.0 6.0 6 0 0 6 6 6 3 Leucine Rich repeat LRR_1 PF00560.33 EAQ93573.1 - 6.7e-05 22.9 4.6 30 5.7 0.0 6.3 5 1 0 5 5 5 1 Leucine Rich Repeat MaoC_dehydratas PF01575.19 EAQ93574.1 - 1.3e-23 82.9 0.0 2.2e-23 82.1 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 EAQ93574.1 - 5.9e-06 26.4 0.0 0.0033 17.6 0.0 2.3 2 0 0 2 2 2 2 N-terminal half of MaoC dehydratase TFIIA PF03153.13 EAQ93575.1 - 0.67 9.9 6.5 0.71 9.8 6.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit WD40 PF00400.32 EAQ93576.1 - 1.1e-07 32.4 6.7 0.58 11.1 0.5 5.9 6 1 0 6 6 6 3 WD domain, G-beta repeat MtaB PF12176.8 EAQ93576.1 - 0.04 12.7 0.1 0.065 12.0 0.1 1.2 1 0 0 1 1 1 0 Methanol-cobalamin methyltransferase B subunit ATP-synt_E PF05680.12 EAQ93577.1 - 1.6e-25 89.2 0.3 1.8e-25 89.1 0.3 1.0 1 0 0 1 1 1 1 ATP synthase E chain Lipoprotein_3 PF00938.17 EAQ93577.1 - 0.0053 16.9 1.0 0.0087 16.2 1.0 1.3 1 0 0 1 1 1 1 Lipoprotein DUF349 PF03993.12 EAQ93577.1 - 0.013 15.7 1.1 0.017 15.4 1.1 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF349) Drf_GBD PF06371.13 EAQ93577.1 - 0.043 13.4 0.1 0.047 13.3 0.1 1.1 1 0 0 1 1 1 0 Diaphanous GTPase-binding Domain DUF1656 PF07869.12 EAQ93579.1 - 0.075 13.1 2.3 0.13 12.3 2.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1656) PGA2 PF07543.12 EAQ93579.1 - 0.15 12.1 3.8 0.24 11.4 3.8 1.3 1 0 0 1 1 1 0 Protein trafficking PGA2 CENP-B_dimeris PF09026.10 EAQ93579.1 - 0.31 11.4 9.2 0.62 10.5 9.2 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Nop14 PF04147.12 EAQ93579.1 - 2.8 6.0 10.2 3.5 5.7 10.2 1.1 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.12 EAQ93579.1 - 9 5.5 13.1 13 5.0 13.1 1.1 1 0 0 1 1 1 0 NOA36 protein Acetyltransf_3 PF13302.7 EAQ93581.1 - 7.1e-21 75.3 0.0 8.6e-21 75.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Ribosomal_L18A PF01775.17 EAQ93582.1 - 8.5e-55 184.0 0.3 1.1e-54 183.7 0.3 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A PCI PF01399.27 EAQ93583.1 - 1.1e-13 51.6 0.0 5.5e-13 49.3 0.0 2.3 2 0 0 2 2 2 1 PCI domain BTB PF00651.31 EAQ93584.1 - 8.1e-10 38.9 0.2 3.8e-09 36.8 0.0 2.1 3 0 0 3 3 3 1 BTB/POZ domain Hydrolase_4 PF12146.8 EAQ93585.1 - 0.0032 16.7 0.1 0.16 11.2 0.0 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 EAQ93585.1 - 0.05 13.5 0.0 0.093 12.6 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold LRR_4 PF12799.7 EAQ93586.1 - 1.2e-42 143.2 41.2 9e-08 32.3 1.1 6.3 1 1 10 11 11 11 10 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EAQ93586.1 - 6.3e-21 73.9 27.2 2.1e-07 30.6 4.8 5.5 3 2 2 5 5 5 4 Leucine rich repeat LRR_9 PF14580.6 EAQ93586.1 - 5.8e-15 55.2 7.6 4.1e-06 26.4 2.2 4.4 1 1 3 4 4 4 4 Leucine-rich repeat LRR_6 PF13516.6 EAQ93586.1 - 6.9e-06 25.7 17.5 0.31 11.2 0.4 7.2 8 0 0 8 8 8 2 Leucine Rich repeat LRR_1 PF00560.33 EAQ93586.1 - 0.079 13.6 20.9 8 7.5 0.4 7.2 8 1 0 8 8 8 0 Leucine Rich Repeat DUF1233 PF06806.12 EAQ93586.1 - 0.14 11.7 0.1 2.2 8.0 0.0 2.7 3 0 0 3 3 3 0 Putative excisionase (DUF1233) Aldo_ket_red PF00248.21 EAQ93587.1 - 4.5e-43 147.5 0.0 5.5e-43 147.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Yos1 PF08571.10 EAQ93588.1 - 9.9e-12 45.0 0.0 1.1e-11 44.9 0.0 1.0 1 0 0 1 1 1 1 Yos1-like UCH PF00443.29 EAQ93589.1 - 5.9e-54 183.3 0.0 5.9e-54 183.3 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EAQ93589.1 - 1.4e-23 84.0 9.5 1.5e-19 70.8 0.1 2.7 3 0 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase Borrelia_P83 PF05262.11 EAQ93589.1 - 0.35 9.3 14.3 0.54 8.7 14.3 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein Peptidase_C98 PF15499.6 EAQ93589.1 - 1.7 8.1 11.9 0.73 9.2 0.9 3.6 4 0 0 4 4 4 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Sec61_beta PF03911.16 EAQ93590.1 - 3.1e-19 68.7 1.9 4.2e-19 68.3 1.9 1.2 1 0 0 1 1 1 1 Sec61beta family DUF1180 PF06679.12 EAQ93590.1 - 0.13 12.6 2.1 0.16 12.4 2.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) NIF PF03031.18 EAQ93591.1 - 2.2e-45 154.2 0.0 3.1e-45 153.7 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase ABC_membrane_2 PF06472.15 EAQ93592.1 - 7.3e-92 307.6 0.6 9e-91 304.0 0.0 2.3 2 0 0 2 2 2 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 EAQ93592.1 - 1e-14 55.2 0.0 2.5e-14 53.9 0.0 1.7 1 0 0 1 1 1 1 ABC transporter RuvB_N PF05496.12 EAQ93592.1 - 0.0073 16.1 0.0 0.063 13.0 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_23 PF13476.6 EAQ93592.1 - 0.04 14.4 0.2 0.68 10.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EAQ93592.1 - 0.055 13.9 0.0 0.2 12.1 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 EAQ93592.1 - 0.083 12.6 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.29 EAQ93592.1 - 0.11 13.0 0.0 0.29 11.6 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EAQ93592.1 - 0.11 12.2 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Mg_chelatase PF01078.21 EAQ93592.1 - 0.15 11.4 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PP2C PF00481.21 EAQ93593.1 - 1e-56 192.5 0.0 1.7e-56 191.7 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_8 PF13855.6 EAQ93593.1 - 5.1e-44 147.9 48.1 5.4e-11 42.1 0.1 9.1 4 3 4 10 10 10 9 Leucine rich repeat LRR_4 PF12799.7 EAQ93593.1 - 1.2e-34 117.7 53.4 0.00031 21.1 0.6 11.9 10 2 2 12 12 12 9 Leucine Rich repeats (2 copies) Guanylate_cyc PF00211.20 EAQ93593.1 - 8e-24 84.3 0.0 3.9e-23 82.0 0.0 1.9 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain Ad_cyc_g-alpha PF08509.11 EAQ93593.1 - 6.8e-23 80.1 1.9 2.6e-22 78.3 1.9 2.1 1 0 0 1 1 1 1 Adenylate cyclase G-alpha binding domain LRR_1 PF00560.33 EAQ93593.1 - 2.8e-08 33.2 37.5 18 6.4 0.0 15.5 13 4 0 13 13 13 1 Leucine Rich Repeat LRR_9 PF14580.6 EAQ93593.1 - 8.9e-07 28.6 13.3 0.01 15.3 0.2 4.1 2 1 2 4 4 4 3 Leucine-rich repeat LRR_6 PF13516.6 EAQ93593.1 - 1.8e-05 24.4 39.2 6.4 7.1 0.2 12.6 13 0 0 13 13 13 2 Leucine Rich repeat RA PF00788.23 EAQ93593.1 - 0.0016 19.0 0.1 0.0045 17.6 0.1 1.8 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain RTC4 PF14474.6 EAQ93595.1 - 3.6e-32 111.1 0.0 6.3e-32 110.3 0.0 1.4 1 0 0 1 1 1 1 RTC4-like domain Dynamitin PF04912.14 EAQ93596.1 - 5.3e-89 299.3 3.5 7.2e-89 298.8 3.5 1.2 1 0 0 1 1 1 1 Dynamitin ThiS PF02597.20 EAQ93596.1 - 8.2e-05 23.2 2.5 0.00011 22.8 0.0 2.6 3 1 0 3 3 3 1 ThiS family FlgN PF05130.12 EAQ93596.1 - 0.0074 16.8 0.8 0.0074 16.8 0.8 2.9 3 0 0 3 3 3 1 FlgN protein Snapin_Pallidin PF14712.6 EAQ93596.1 - 0.23 11.9 2.5 4 7.9 0.0 3.0 3 1 0 3 3 3 0 Snapin/Pallidin DASH_Spc19 PF08287.11 EAQ93596.1 - 0.24 11.3 11.2 1.8 8.4 1.5 2.6 2 1 0 2 2 2 0 Spc19 DUF3053 PF11254.8 EAQ93596.1 - 0.44 10.1 4.8 1.5 8.3 0.3 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3053) FH2 PF02181.23 EAQ93596.1 - 0.72 8.9 0.0 0.72 8.9 0.0 2.1 3 0 0 3 3 3 0 Formin Homology 2 Domain DUF4407 PF14362.6 EAQ93596.1 - 0.73 9.1 7.6 5 6.4 1.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Wtap PF17098.5 EAQ93596.1 - 0.87 9.5 7.1 13 5.7 0.1 3.1 3 0 0 3 3 3 0 WTAP/Mum2p family HAMP PF00672.25 EAQ93596.1 - 0.88 10.0 3.5 7.7 7.0 0.0 3.0 3 0 0 3 3 3 0 HAMP domain CENP-H PF05837.12 EAQ93596.1 - 1.2 9.5 9.2 3 8.3 0.4 3.2 3 0 0 3 3 3 0 Centromere protein H (CENP-H) ZapB PF06005.12 EAQ93596.1 - 1.8 9.0 12.5 15 6.1 0.0 3.7 3 0 0 3 3 3 0 Cell division protein ZapB DUF2203 PF09969.9 EAQ93596.1 - 2 9.2 10.1 22 5.8 0.7 3.4 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) DivIC PF04977.15 EAQ93596.1 - 2.6 7.9 12.3 1.1 9.0 0.6 3.4 3 0 0 3 3 3 0 Septum formation initiator Cep57_MT_bd PF06657.13 EAQ93596.1 - 2.6 8.5 9.8 4.5 7.8 1.3 4.3 4 1 0 4 4 4 0 Centrosome microtubule-binding domain of Cep57 GrpE PF01025.19 EAQ93596.1 - 4.3 7.0 6.1 2.2 7.9 0.9 2.7 3 0 0 3 3 3 0 GrpE CorA PF01544.18 EAQ93596.1 - 4.3 6.6 7.8 0.89 8.8 0.9 2.5 2 1 0 2 2 2 0 CorA-like Mg2+ transporter protein ATP-synt_E PF05680.12 EAQ93596.1 - 5.2 7.5 7.5 0.78 10.1 1.5 2.4 2 0 0 2 2 2 0 ATP synthase E chain Packaging_FI PF14000.6 EAQ93596.1 - 7.4 7.0 7.7 3.2 8.2 0.7 2.9 3 0 0 3 3 3 0 DNA packaging protein FI COG4 PF08318.12 EAQ93597.1 - 4.4e-121 404.1 0.0 8.8e-121 403.1 0.0 1.5 1 0 0 1 1 1 1 COG4 transport protein Dynamin_N PF00350.23 EAQ93597.1 - 2.2e-31 109.2 0.0 5.8e-31 107.8 0.0 1.8 1 1 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 EAQ93597.1 - 8.1e-18 64.6 0.0 3e-17 62.8 0.0 1.9 2 0 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.23 EAQ93597.1 - 0.0003 20.9 0.0 0.007 16.4 0.0 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase DLIC PF05783.11 EAQ93597.1 - 0.013 14.4 4.0 0.042 12.7 0.0 2.2 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) ABC_tran PF00005.27 EAQ93597.1 - 0.026 15.1 0.0 0.091 13.3 0.0 1.9 1 0 0 1 1 1 0 ABC transporter HSCB_C PF07743.13 EAQ93597.1 - 0.039 14.5 1.9 1.3 9.6 0.1 3.8 3 0 0 3 3 3 0 HSCB C-terminal oligomerisation domain Roc PF08477.13 EAQ93597.1 - 0.048 13.9 0.0 0.11 12.7 0.0 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EAQ93597.1 - 0.13 11.9 0.0 0.31 10.6 0.0 1.7 1 0 0 1 1 1 0 Ras family Pex19 PF04614.12 EAQ93597.1 - 0.68 9.7 6.2 2.3 7.9 0.1 2.3 2 0 0 2 2 2 0 Pex19 protein family E1-E2_ATPase PF00122.20 EAQ93598.1 - 2.8e-45 154.1 0.1 7.4e-45 152.7 0.1 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 EAQ93598.1 - 8e-41 139.7 0.1 8e-41 139.7 0.1 1.6 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Cation_ATPase_N PF00690.26 EAQ93598.1 - 2.1e-19 69.0 0.0 4.4e-19 67.9 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase PF00702.26 EAQ93598.1 - 9.6e-19 68.5 5.1 5.7e-18 66.0 3.5 2.9 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EAQ93598.1 - 2.2e-06 27.7 0.0 4.7e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EAQ93598.1 - 4.4e-05 23.4 1.1 8e-05 22.5 1.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Rad21_Rec8_N PF04825.13 EAQ93600.1 - 1.3e-33 115.4 0.0 2.4e-33 114.6 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 EAQ93600.1 - 4.2e-08 32.4 0.1 1.1e-07 31.0 0.1 1.7 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein Peptidase_S9 PF00326.21 EAQ93601.1 - 7.9e-46 156.2 0.0 2.8e-45 154.4 0.0 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family COesterase PF00135.28 EAQ93601.1 - 3.4e-06 26.2 0.0 5.2e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family AXE1 PF05448.12 EAQ93601.1 - 0.19 10.3 0.0 0.35 9.5 0.0 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) NuA4 PF09340.10 EAQ93602.1 - 1.5e-24 85.6 0.0 2.6e-24 84.9 0.0 1.4 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 YPEB PF14620.6 EAQ93602.1 - 0.11 11.8 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 YpeB sporulation PspB PF06667.12 EAQ93602.1 - 0.22 11.6 0.1 0.34 11.0 0.1 1.2 1 0 0 1 1 1 0 Phage shock protein B PWI PF01480.17 EAQ93603.1 - 8.7e-30 102.9 0.1 1.3e-29 102.3 0.1 1.3 1 0 0 1 1 1 1 PWI domain FAA_hydrolase PF01557.18 EAQ93605.1 - 1.1e-50 172.3 0.0 1.3e-50 172.1 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family 3-HAO PF06052.12 EAQ93606.1 - 3.3e-59 198.9 0.0 3.8e-59 198.7 0.0 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_1 PF00190.22 EAQ93606.1 - 2e-06 27.5 0.0 3e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 EAQ93606.1 - 6.5e-06 25.8 0.0 1e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 EAQ93606.1 - 0.0028 17.5 0.0 0.0042 17.0 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain ARD PF03079.14 EAQ93606.1 - 0.051 13.7 0.0 0.084 13.0 0.0 1.3 1 0 0 1 1 1 0 ARD/ARD' family Cupin_4 PF08007.12 EAQ93606.1 - 0.096 12.1 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Cupin superfamily protein DZR PF12773.7 EAQ93606.1 - 0.39 10.8 4.4 0.79 9.8 4.4 1.5 1 0 0 1 1 1 0 Double zinc ribbon IBR PF01485.21 EAQ93606.1 - 0.43 10.8 3.5 1.5 9.1 3.1 2.0 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain WD40 PF00400.32 EAQ93608.1 - 2.9e-89 290.6 22.5 3.9e-11 43.3 0.3 8.9 8 0 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAQ93608.1 - 1.7e-33 114.7 7.3 0.0016 18.7 0.1 7.7 2 1 6 8 8 7 7 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EAQ93608.1 - 2.1e-15 56.5 14.3 0.36 9.7 0.1 7.3 1 1 6 7 7 7 7 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 EAQ93608.1 - 4.5e-13 48.8 0.0 10 6.2 0.0 7.6 7 0 0 7 7 7 2 WD40-like Beta Propeller Repeat NACHT PF05729.12 EAQ93608.1 - 6.8e-09 35.9 0.0 1.4e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EAQ93608.1 - 9.7e-07 29.3 2.5 5.2e-06 26.9 0.0 3.2 3 2 0 3 3 3 1 AAA ATPase domain Tli4_C PF18426.1 EAQ93608.1 - 3.1e-06 27.6 1.9 29 4.9 0.0 6.8 7 0 0 7 7 7 0 Tle cognate immunity protein 4 C-terminal domain NYD-SP28_assoc PF14775.6 EAQ93608.1 - 4.3e-05 23.5 7.6 53 4.0 0.0 8.2 8 0 0 8 8 8 0 Sperm tail C-terminal domain DUF1258 PF06869.12 EAQ93608.1 - 0.0005 19.6 0.1 4.9 6.5 0.0 4.6 1 1 6 7 7 7 1 Protein of unknown function (DUF1258) DUF815 PF05673.13 EAQ93608.1 - 0.02 14.0 0.0 0.04 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) HARP PF07443.13 EAQ93608.1 - 0.027 14.1 0.0 64 3.3 0.0 4.1 4 0 0 4 4 4 0 HepA-related protein (HARP) WD40_like PF17005.5 EAQ93608.1 - 0.039 13.3 0.0 27 3.9 0.0 3.6 4 1 1 5 5 5 0 WD40-like domain Cutinase PF01083.22 EAQ93608.1 - 0.04 13.9 0.4 1.3e+02 2.4 0.0 4.7 1 1 5 6 6 6 0 Cutinase NB-ARC PF00931.22 EAQ93608.1 - 0.055 12.6 0.0 0.17 11.1 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain DUF746 PF05344.11 EAQ93608.1 - 0.058 13.2 0.3 5.4 6.9 0.1 4.0 4 0 0 4 4 4 0 Domain of Unknown Function (DUF746) KAP_NTPase PF07693.14 EAQ93608.1 - 0.11 11.8 0.2 0.24 10.6 0.2 1.5 1 0 0 1 1 1 0 KAP family P-loop domain CbiA PF01656.23 EAQ93608.1 - 0.12 12.4 0.6 0.8 9.8 0.2 2.4 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain EXS PF03124.14 EAQ93609.1 - 6.9e-105 351.0 9.9 7.8e-105 350.8 9.9 1.0 1 0 0 1 1 1 1 EXS family Pex2_Pex12 PF04757.14 EAQ93610.1 - 6.1e-41 140.5 0.0 7.6e-41 140.2 0.0 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.6 EAQ93610.1 - 6.8e-07 29.0 2.9 1.2e-06 28.2 2.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EAQ93610.1 - 2.6e-06 27.4 3.1 4.9e-06 26.5 3.1 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EAQ93610.1 - 4.1e-05 23.4 3.5 8e-05 22.4 3.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EAQ93610.1 - 4.4e-05 23.6 1.6 7.5e-05 22.8 1.6 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 EAQ93610.1 - 8e-05 22.4 2.3 0.00012 21.9 2.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EAQ93610.1 - 9.8e-05 22.6 2.2 0.00018 21.8 2.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 EAQ93610.1 - 0.00031 20.6 2.0 0.0006 19.7 2.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EAQ93610.1 - 0.019 14.8 2.6 0.03 14.2 2.6 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 CBP_BcsF PF11120.8 EAQ93610.1 - 0.14 12.3 1.5 0.31 11.2 1.5 1.5 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsF zf-LYAR PF08790.11 EAQ93611.1 - 2.7e-08 33.6 0.2 5.6e-08 32.6 0.2 1.6 1 0 0 1 1 1 1 LYAR-type C2HC zinc finger LAT2 PF15703.5 EAQ93611.1 - 0.52 10.2 7.6 0.58 10.0 1.5 2.3 2 0 0 2 2 2 0 Linker for activation of T-cells family member 2 Hydrolase_4 PF12146.8 EAQ93612.1 - 2e-17 63.3 0.0 1.1e-13 51.1 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EAQ93612.1 - 6.2e-12 45.7 0.2 2.2e-08 34.0 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EAQ93612.1 - 1.8e-07 32.0 0.2 2.9e-06 28.1 0.0 1.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family DUF818 PF05677.12 EAQ93612.1 - 5.9e-06 25.5 0.0 8.2e-06 25.0 0.0 1.1 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) AXE1 PF05448.12 EAQ93612.1 - 0.00013 20.8 0.3 0.6 8.7 0.1 3.0 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) FSH1 PF03959.13 EAQ93612.1 - 0.0017 18.0 0.0 0.0091 15.7 0.0 2.0 2 1 0 2 2 2 1 Serine hydrolase (FSH1) DLH PF01738.18 EAQ93612.1 - 0.0022 17.6 0.0 0.021 14.4 0.0 2.1 1 1 0 1 1 1 1 Dienelactone hydrolase family BAAT_C PF08840.11 EAQ93612.1 - 0.01 15.8 0.0 0.1 12.5 0.0 2.4 3 0 0 3 3 3 0 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.21 EAQ93612.1 - 0.059 12.8 0.0 0.26 10.7 0.0 1.9 1 1 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 EAQ93612.1 - 0.085 12.7 0.2 0.28 11.0 0.2 1.9 2 1 0 2 2 2 0 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 EAQ93612.1 - 0.11 12.1 0.0 7.3 6.1 0.0 2.1 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) R3H PF01424.22 EAQ93613.1 - 6.8e-16 58.0 0.0 1.8e-15 56.7 0.0 1.8 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.17 EAQ93613.1 - 0.0036 17.3 13.7 0.0036 17.3 13.7 14.2 13 1 1 14 14 14 5 NF-X1 type zinc finger PTPA PF03095.15 EAQ93615.1 - 2.1e-114 382.0 0.0 2.5e-114 381.8 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein RNase_PH PF01138.21 EAQ93616.1 - 1.1e-13 51.9 0.0 2e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 EAQ93616.1 - 0.038 14.0 0.0 0.071 13.2 0.0 1.5 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 DUF3042 PF11240.8 EAQ93616.1 - 0.31 11.1 1.4 1.2 9.3 1.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3042) NAD_kinase PF01513.21 EAQ93617.1 - 1.2e-78 264.3 0.0 6.5e-78 261.9 0.0 1.9 1 1 1 2 2 2 1 ATP-NAD kinase Homeodomain PF00046.29 EAQ93618.1 - 5.3e-09 35.8 1.3 1.4e-08 34.4 1.3 1.7 1 0 0 1 1 1 1 Homeodomain zf-GRF PF06839.12 EAQ93618.1 - 2.5e-08 33.8 3.5 5e-08 32.9 3.5 1.5 1 0 0 1 1 1 1 GRF zinc finger PH_12 PF16457.5 EAQ93619.1 - 8.1e-38 130.0 0.2 1.6e-36 125.8 0.0 2.6 2 1 0 2 2 2 1 Pleckstrin homology domain ELMO_CED12 PF04727.13 EAQ93619.1 - 1.6e-21 77.2 0.0 1.3e-20 74.3 0.0 2.0 2 0 0 2 2 2 1 ELMO/CED-12 family DUF3361 PF11841.8 EAQ93619.1 - 2.3e-13 50.4 0.0 1.6e-08 34.6 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3361) Amidase PF01425.21 EAQ93619.1 - 0.53 9.2 2.2 0.89 8.4 2.2 1.3 1 0 0 1 1 1 0 Amidase FAD_binding_4 PF01565.23 EAQ93620.1 - 6.5e-19 68.1 0.1 1e-18 67.4 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain C2 PF00168.30 EAQ93621.1 - 7.7e-80 263.8 0.0 2.9e-21 75.7 0.0 5.5 5 0 0 5 5 5 5 C2 domain SMP_LBD PF17047.5 EAQ93621.1 - 0.00018 21.0 0.0 0.00033 20.2 0.0 1.3 1 0 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain NT-C2 PF10358.9 EAQ93621.1 - 0.066 12.9 0.0 0.46 10.2 0.0 2.3 2 0 0 2 2 2 0 N-terminal C2 in EEIG1 and EHBP1 proteins MLVIN_C PF18697.1 EAQ93621.1 - 0.09 12.9 0.1 4.2 7.5 0.1 3.0 2 0 0 2 2 2 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain zf-CCCH PF00642.24 EAQ93622.1 - 2.9e-08 33.4 20.0 2.9e-07 30.2 2.5 3.1 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.22 EAQ93622.1 - 0.0028 17.4 0.0 0.0044 16.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 EAQ93622.1 - 0.0057 16.7 3.3 0.0057 16.7 3.3 3.3 3 0 0 3 3 3 1 Zinc finger domain Torus PF16131.5 EAQ93622.1 - 0.023 15.4 3.7 0.48 11.1 0.2 2.4 2 0 0 2 2 2 0 Torus domain SCRG1 PF15224.6 EAQ93622.1 - 0.17 12.0 3.7 0.2 11.8 0.1 2.3 2 0 0 2 2 2 0 Scrapie-responsive protein 1 zf-CCCH_3 PF15663.5 EAQ93622.1 - 0.18 12.1 4.8 0.19 12.0 1.0 2.3 2 0 0 2 2 2 0 Zinc-finger containing family Oxysterol_BP PF01237.18 EAQ93624.1 - 6.2e-58 196.4 0.4 1.1e-47 162.7 0.0 2.7 1 1 2 3 3 3 2 Oxysterol-binding protein DUF3729 PF12526.8 EAQ93624.1 - 1 11.0 12.9 2.2 9.9 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3729) Abhydrolase_1 PF00561.20 EAQ93625.1 - 0.042 13.5 0.0 0.064 12.9 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EAQ93625.1 - 0.12 11.6 0.0 0.46 9.7 0.0 1.7 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Ammonium_transp PF00909.21 EAQ93626.1 - 1.1e-111 373.4 24.4 1.4e-111 373.0 24.4 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family CRT10 PF08728.10 EAQ93627.1 - 1.6e-18 66.3 0.0 2.5e-10 39.2 0.0 2.1 2 0 0 2 2 2 2 CRT10 Cellulase PF00150.18 EAQ93628.1 - 4.8e-11 42.6 0.0 1.7e-10 40.8 0.0 1.8 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) 7tm_2 PF00002.24 EAQ93629.1 - 3e-06 26.7 12.7 6.7e-06 25.6 12.6 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (Secretin family) L6_membrane PF05805.12 EAQ93629.1 - 0.0032 17.1 2.4 0.0078 15.8 1.6 2.0 1 1 1 2 2 2 1 L6 membrane protein Dicty_CAR PF05462.11 EAQ93629.1 - 0.047 12.8 4.6 0.079 12.1 4.6 1.4 1 0 0 1 1 1 0 Slime mold cyclic AMP receptor DC_STAMP PF07782.13 EAQ93629.1 - 0.25 11.2 1.3 1.2 9.0 0.1 2.6 3 0 0 3 3 3 0 DC-STAMP-like protein TauD PF02668.16 EAQ93631.1 - 2.9e-24 86.3 0.2 5.9e-24 85.3 0.2 1.5 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 EAQ93631.1 - 0.022 13.9 0.0 0.033 13.3 0.0 1.2 1 0 0 1 1 1 0 CsiD ATG13 PF10033.9 EAQ93632.1 - 0.024 14.3 0.1 0.024 14.3 0.1 1.1 1 0 0 1 1 1 0 Autophagy-related protein 13 Exo_endo_phos PF03372.23 EAQ93636.1 - 2e-15 57.0 0.0 5.1e-15 55.6 0.0 1.7 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Dicty_REP PF05086.12 EAQ93636.1 - 3.3 5.6 6.6 4.5 5.1 6.6 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Pcc1 PF09341.10 EAQ93639.1 - 6e-27 93.6 1.7 1.1e-26 92.8 1.7 1.4 1 0 0 1 1 1 1 Transcription factor Pcc1 DSPn PF14671.6 EAQ93640.1 - 7.5e-42 143.1 0.0 4.6e-39 134.1 0.0 2.9 2 1 0 2 2 2 2 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 EAQ93640.1 - 3e-17 62.7 0.0 5.4e-17 61.9 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EAQ93640.1 - 2.1e-06 27.5 0.0 3.9e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase SWIM PF04434.17 EAQ93641.1 - 0.0034 17.0 0.1 0.0062 16.2 0.1 1.4 1 0 0 1 1 1 1 SWIM zinc finger Vac7 PF12751.7 EAQ93641.1 - 0.49 9.8 2.2 1.2 8.4 0.2 2.1 2 0 0 2 2 2 0 Vacuolar segregation subunit 7 Sulfate_transp PF00916.20 EAQ93642.1 - 3.4e-101 338.7 23.6 4.3e-101 338.4 23.6 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 EAQ93642.1 - 1.2e-07 31.4 0.0 2.1e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 STAS domain SNN_transmemb PF09049.10 EAQ93642.1 - 1.1 9.2 9.4 0.35 10.8 0.8 3.6 3 0 0 3 3 3 0 Stannin transmembrane RabGAP-TBC PF00566.18 EAQ93644.1 - 1.7e-33 116.1 0.0 3.4e-27 95.5 0.0 2.3 2 0 0 2 2 2 2 Rab-GTPase-TBC domain PX PF00787.24 EAQ93644.1 - 0.13 12.3 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 PX domain Peptidase_C69 PF03577.15 EAQ93644.1 - 0.17 10.8 0.1 0.27 10.1 0.1 1.2 1 0 0 1 1 1 0 Peptidase family C69 TFIIA PF03153.13 EAQ93644.1 - 0.78 9.7 11.0 1.2 9.0 11.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit HlyIII PF03006.20 EAQ93645.1 - 3e-62 210.3 18.0 3.6e-62 210.0 18.0 1.1 1 0 0 1 1 1 1 Haemolysin-III related FtsK_SpoIIIE PF01580.18 EAQ93645.1 - 0.17 11.2 1.4 0.54 9.6 0.7 2.0 1 1 1 2 2 2 0 FtsK/SpoIIIE family An_peroxidase PF03098.15 EAQ93645.1 - 0.18 10.4 0.0 0.24 9.9 0.0 1.1 1 0 0 1 1 1 0 Animal haem peroxidase Exonuc_VII_L PF02601.15 EAQ93645.1 - 0.22 11.1 0.8 0.3 10.6 0.8 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF883 PF05957.13 EAQ93645.1 - 3.2 8.4 7.5 14 6.4 2.5 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) FmiP_Thoc5 PF09766.9 EAQ93646.1 - 1.5e-33 116.6 11.7 1.9e-33 116.3 11.7 1.1 1 0 0 1 1 1 1 Fms-interacting protein/Thoc5 Glyco_hydro_3_C PF01915.22 EAQ93646.1 - 0.12 12.3 0.2 0.17 11.8 0.2 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain TSC22 PF01166.18 EAQ93646.1 - 0.22 11.9 6.5 0.75 10.2 0.1 2.5 2 0 0 2 2 2 0 TSC-22/dip/bun family CENP-F_leu_zip PF10473.9 EAQ93646.1 - 0.24 11.4 11.1 0.65 10.0 5.0 2.3 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DivIC PF04977.15 EAQ93646.1 - 0.27 11.0 7.0 2.1 8.2 3.8 2.5 2 0 0 2 2 2 0 Septum formation initiator DUF641 PF04859.12 EAQ93646.1 - 0.62 10.4 8.7 0.66 10.3 0.2 2.2 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) Casc1_N PF15927.5 EAQ93646.1 - 6 6.5 13.7 0.24 11.1 7.7 1.7 2 0 0 2 2 2 0 Cancer susceptibility candidate 1 N-terminus Glyco_trans_2_3 PF13632.6 EAQ93648.1 - 1.8e-18 67.2 0.2 1.8e-18 67.2 0.2 1.9 2 0 0 2 2 2 1 Glycosyl transferase family group 2 DJ-1_PfpI PF01965.24 EAQ93649.1 - 5.6e-11 42.5 0.0 7.3e-11 42.2 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family FKBP_C PF00254.28 EAQ93650.1 - 4.2e-32 110.3 0.0 1.3e-30 105.5 0.0 2.4 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase NPL PF17800.1 EAQ93650.1 - 2.2e-31 108.5 3.0 2.2e-31 108.5 3.0 2.8 2 2 0 2 2 2 1 Nucleoplasmin-like domain CinA PF02464.17 EAQ93651.1 - 2.3e-31 108.4 9.9 3.6e-24 85.1 2.2 2.4 2 0 0 2 2 2 2 Competence-damaged protein Pkinase PF00069.25 EAQ93651.1 - 2.1e-22 79.8 0.0 1e-17 64.4 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ93651.1 - 9e-06 25.1 0.0 2.7e-05 23.6 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase zf-UBR PF02207.20 EAQ93652.1 - 3.7e-19 68.6 15.1 9.5e-19 67.3 15.1 1.8 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 EAQ93652.1 - 1.7e-05 24.5 0.0 5.3e-05 22.9 0.0 1.9 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS zf-RING_2 PF13639.6 EAQ93652.1 - 0.012 16.0 0.7 0.012 16.0 0.7 4.1 4 1 1 5 5 5 0 Ring finger domain UCR_UQCRX_QCR9 PF05365.12 EAQ93653.1 - 3.3e-26 91.0 2.9 3.9e-26 90.8 2.9 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Mago-bind PF09282.10 EAQ93654.1 - 4.6e-15 55.2 4.0 9.8e-15 54.1 4.0 1.6 1 0 0 1 1 1 1 Mago binding Nucleo_P87 PF07267.11 EAQ93654.1 - 0.26 10.1 5.8 0.28 10.0 5.8 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF4407 PF14362.6 EAQ93654.1 - 2.5 7.3 6.3 2.8 7.2 6.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Presenilin PF01080.17 EAQ93654.1 - 6.1 5.5 4.8 6.7 5.4 4.8 1.1 1 0 0 1 1 1 0 Presenilin BCS1_N PF08740.11 EAQ93655.1 - 7.9e-40 136.8 0.0 1.1e-39 136.3 0.0 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 EAQ93655.1 - 7.6e-21 74.9 0.0 1.1e-20 74.4 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EAQ93655.1 - 1.2e-05 25.1 0.0 2.1e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EAQ93655.1 - 5.6e-05 23.6 0.0 0.00012 22.6 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 EAQ93655.1 - 0.00011 22.2 0.0 0.00028 20.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 EAQ93655.1 - 0.0002 20.9 0.0 0.00037 20.1 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 EAQ93655.1 - 0.00022 21.5 0.0 0.00044 20.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 EAQ93655.1 - 0.0021 17.3 0.0 0.0031 16.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 EAQ93655.1 - 0.0031 18.0 0.0 0.0057 17.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 EAQ93655.1 - 0.006 16.3 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAQ93655.1 - 0.015 15.1 0.0 0.021 14.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 EAQ93655.1 - 0.017 15.6 0.1 1.8 9.0 0.0 2.4 1 1 1 2 2 2 0 AAA domain Rad17 PF03215.15 EAQ93655.1 - 0.02 14.8 0.0 0.031 14.2 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_25 PF13481.6 EAQ93655.1 - 0.029 14.0 0.0 0.066 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EAQ93655.1 - 0.033 14.3 0.0 0.079 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 EAQ93655.1 - 0.038 13.3 0.0 0.069 12.5 0.0 1.4 1 0 0 1 1 1 0 KaiC RNA_helicase PF00910.22 EAQ93655.1 - 0.044 14.2 0.0 0.087 13.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_28 PF13521.6 EAQ93655.1 - 0.045 14.0 0.0 0.085 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EAQ93655.1 - 0.047 14.2 0.0 0.11 13.0 0.0 1.6 2 0 0 2 2 1 0 ABC transporter AAA_21 PF13304.6 EAQ93655.1 - 0.059 13.2 0.1 0.66 9.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_6 PF12774.7 EAQ93655.1 - 0.081 11.9 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region AAA_19 PF13245.6 EAQ93655.1 - 0.088 13.1 1.4 1.4 9.2 0.1 2.4 1 1 1 2 2 2 0 AAA domain AAA_3 PF07726.11 EAQ93655.1 - 0.096 12.5 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 EAQ93655.1 - 0.12 12.3 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 EAQ93655.1 - 0.13 12.0 0.0 0.28 10.9 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein PPV_E1_C PF00519.17 EAQ93655.1 - 0.25 10.1 0.0 0.37 9.6 0.0 1.1 1 0 0 1 1 1 0 Papillomavirus helicase Tim44 PF04280.15 EAQ93656.1 - 2.4e-36 125.0 0.0 6.3e-36 123.7 0.0 1.8 1 0 0 1 1 1 1 Tim44-like domain DUF1768 PF08719.11 EAQ93657.1 - 3.2e-56 190.0 0.0 4.1e-56 189.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) ABC_tran PF00005.27 EAQ93658.1 - 2.8e-32 112.1 0.0 5.4e-32 111.2 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 EAQ93658.1 - 6.3e-20 71.9 8.5 6.3e-20 71.9 8.5 2.3 2 0 0 2 2 2 1 ABC transporter transmembrane region SMC_N PF02463.19 EAQ93658.1 - 3.9e-06 26.5 0.1 4.8e-05 22.9 0.0 2.1 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain PAM2 PF07145.15 EAQ93658.1 - 0.00036 20.0 0.3 0.00074 19.0 0.3 1.6 1 0 0 1 1 1 1 Ataxin-2 C-terminal region AAA_15 PF13175.6 EAQ93658.1 - 0.00099 18.9 0.0 0.0019 18.0 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 EAQ93658.1 - 0.0044 16.9 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase Zeta_toxin PF06414.12 EAQ93658.1 - 0.005 16.1 0.0 0.0099 15.2 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_21 PF13304.6 EAQ93658.1 - 0.017 14.9 0.0 0.052 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EAQ93658.1 - 0.022 15.3 0.8 0.037 14.5 0.1 1.7 2 0 0 2 2 1 0 AAA domain AAA_22 PF13401.6 EAQ93658.1 - 0.067 13.5 0.0 0.26 11.6 0.0 1.9 2 1 0 2 2 1 0 AAA domain DUF1449 PF07290.11 EAQ93658.1 - 0.075 12.6 2.8 0.8 9.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1449) DUF815 PF05673.13 EAQ93658.1 - 0.084 12.0 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) SbcCD_C PF13558.6 EAQ93658.1 - 0.085 13.1 0.3 1.1 9.6 0.3 2.7 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA PF00004.29 EAQ93658.1 - 0.11 12.9 0.3 0.73 10.3 0.3 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 EAQ93658.1 - 0.11 12.2 0.1 0.29 10.9 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.6 EAQ93658.1 - 0.13 11.9 0.3 0.38 10.4 0.3 1.7 1 1 0 1 1 1 0 AAA domain SpoIIIAH PF12685.7 EAQ93658.1 - 0.19 11.5 6.9 0.12 12.2 0.7 2.2 2 0 0 2 2 2 0 SpoIIIAH-like protein MTABC_N PF16185.5 EAQ93658.1 - 4.9 6.6 10.6 0.46 9.9 0.3 3.3 3 1 0 3 3 3 0 Mitochondrial ABC-transporter N-terminal five TM region adh_short PF00106.25 EAQ93659.1 - 9.3e-31 106.8 0.5 1.6e-30 106.0 0.5 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EAQ93659.1 - 3.5e-23 82.4 5.2 6.6e-23 81.5 5.2 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 EAQ93659.1 - 8.6e-07 29.0 1.3 1.9e-06 27.9 1.3 1.6 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 EAQ93659.1 - 1.5e-06 28.2 0.7 1.5e-06 28.2 0.7 2.0 2 0 0 2 2 2 1 KR domain IQ PF00612.27 EAQ93659.1 - 4.5e-05 22.9 1.3 0.00013 21.5 1.3 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif NmrA PF05368.13 EAQ93659.1 - 0.00022 20.9 1.2 0.00047 19.8 0.8 1.7 2 0 0 2 2 2 1 NmrA-like family Epimerase PF01370.21 EAQ93659.1 - 0.013 15.0 0.4 0.024 14.1 0.4 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.26 EAQ93659.1 - 0.46 10.5 2.3 0.77 9.7 0.5 2.3 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Roughex PF06020.11 EAQ93659.1 - 4.7 6.2 11.0 8 5.5 5.6 2.4 2 0 0 2 2 2 0 Drosophila roughex protein Perilipin PF03036.16 EAQ93659.1 - 5.6 5.9 7.2 0.4 9.6 0.1 2.1 2 0 0 2 2 2 0 Perilipin family adh_short PF00106.25 EAQ93660.1 - 3.3e-21 75.6 0.1 9.4e-12 44.8 0.0 2.2 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EAQ93660.1 - 1.2e-06 28.3 0.1 0.0061 16.1 0.0 2.2 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EAQ93660.1 - 0.061 13.2 0.1 0.45 10.4 0.2 2.0 2 0 0 2 2 2 0 KR domain NAD_binding_10 PF13460.6 EAQ93660.1 - 0.087 12.7 0.2 0.23 11.3 0.2 1.6 2 0 0 2 2 2 0 NAD(P)H-binding Epimerase PF01370.21 EAQ93660.1 - 0.098 12.1 0.0 0.36 10.2 0.0 1.8 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Peptidase_M28 PF04389.17 EAQ93661.1 - 2e-36 125.6 0.0 2.8e-36 125.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 PX PF00787.24 EAQ93662.1 - 9.2e-20 70.7 0.1 1.5e-19 70.0 0.1 1.3 1 0 0 1 1 1 1 PX domain Alpha_GJ PF03229.13 EAQ93664.1 - 9.3 6.8 15.1 0.29 11.7 8.1 2.2 2 2 0 2 2 2 0 Alphavirus glycoprotein J Ribophorin_II PF05817.14 EAQ93665.1 - 1.1e-28 100.2 0.1 1.9e-24 86.2 0.0 2.0 2 0 0 2 2 2 2 Oligosaccharyltransferase subunit Ribophorin II Cep57_MT_bd PF06657.13 EAQ93666.1 - 5.7e-22 78.0 0.1 5.7e-22 78.0 0.1 7.5 8 0 0 8 8 8 2 Centrosome microtubule-binding domain of Cep57 Cep57_CLD_2 PF14197.6 EAQ93666.1 - 4.9e-17 61.8 9.6 4.9e-17 61.8 9.6 7.7 5 1 2 7 7 7 2 Centrosome localisation domain of PPC89 KASH_CCD PF14662.6 EAQ93666.1 - 0.00047 20.0 69.2 0.00051 19.9 35.0 6.3 3 1 1 6 6 6 2 Coiled-coil region of CCDC155 or KASH YabA PF06156.13 EAQ93666.1 - 0.00069 20.2 51.3 0.75 10.5 2.1 7.9 2 1 3 5 5 5 4 Initiation control protein YabA ADIP PF11559.8 EAQ93666.1 - 0.0017 18.5 7.9 0.0017 18.5 7.9 7.6 3 1 4 8 8 8 1 Afadin- and alpha -actinin-Binding MerR_2 PF13591.6 EAQ93666.1 - 0.0059 16.4 2.3 0.0059 16.4 2.3 4.4 5 0 0 5 5 5 1 MerR HTH family regulatory protein Rootletin PF15035.6 EAQ93666.1 - 0.74 9.8 63.9 0.023 14.7 22.1 5.2 2 2 1 4 4 4 0 Ciliary rootlet component, centrosome cohesion DUF4706 PF15797.5 EAQ93666.1 - 2.6 8.6 8.5 3.3 8.3 0.0 3.8 3 1 0 3 3 3 0 Domain of unknown function (DUF4706) DUF3573 PF12097.8 EAQ93666.1 - 3.1 6.5 5.4 5.5 5.7 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3573) Mod_r PF07200.13 EAQ93666.1 - 3.8 7.6 56.2 0.11 12.7 16.8 6.5 2 2 4 6 6 6 0 Modifier of rudimentary (Mod(r)) protein Fungal_trans PF04082.18 EAQ93667.1 - 1.2e-12 47.5 0.5 2e-12 46.8 0.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Beta_elim_lyase PF01212.21 EAQ93668.1 - 1.8e-41 142.4 0.0 2.3e-41 142.0 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 EAQ93668.1 - 0.054 12.7 0.0 0.062 12.5 0.0 1.1 1 0 0 1 1 1 0 Aminotransferase class I and II Trehalase PF01204.18 EAQ93669.1 - 2.4e-85 287.3 7.3 4.1e-44 151.3 13.1 3.6 1 1 1 2 2 2 2 Trehalase Bromodomain PF00439.25 EAQ93670.1 - 1.3e-25 89.2 0.7 2.6e-25 88.3 0.7 1.5 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 EAQ93670.1 - 8.2e-08 32.5 0.0 1.5e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EAQ93670.1 - 6.3e-07 29.4 0.3 1.7e-06 28.0 0.2 1.8 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EAQ93670.1 - 0.00033 21.0 0.3 0.00066 20.1 0.1 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EAQ93670.1 - 0.11 12.5 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Aldedh PF00171.22 EAQ93673.1 - 2.2e-170 567.1 0.0 2.5e-170 566.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Gly_rich_SFCGS PF14272.6 EAQ93673.1 - 0.07 13.1 0.0 0.19 11.8 0.0 1.7 1 0 0 1 1 1 0 Glycine-rich SFCGS DUF126 PF01989.16 EAQ93673.1 - 0.11 12.3 0.3 2.8 7.8 0.1 2.8 2 0 0 2 2 2 0 Aconitase X swivel domain Glyco_hydro_79C PF16862.5 EAQ93674.1 - 2.1e-22 79.9 0.0 4.6e-22 78.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain Glyco_hydro_79n PF03662.14 EAQ93674.1 - 0.069 12.1 0.0 0.25 10.2 0.0 1.8 2 0 0 2 2 2 0 Glycosyl hydrolase family 79, N-terminal domain HATPase_c PF02518.26 EAQ93676.1 - 1.2e-21 77.3 0.0 2.2e-21 76.5 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EAQ93676.1 - 2.8e-18 66.1 0.0 3.1e-14 53.1 0.0 2.6 2 0 0 2 2 2 2 Response regulator receiver domain PAS_4 PF08448.10 EAQ93676.1 - 1.5e-08 34.9 0.0 0.00075 19.7 0.0 2.7 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 EAQ93676.1 - 1.4e-06 28.5 0.0 1.9e-05 24.8 0.0 2.8 3 0 0 3 3 3 1 PAS domain HisKA PF00512.25 EAQ93676.1 - 2.6e-06 27.4 1.4 4.2e-06 26.7 0.0 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_8 PF13188.7 EAQ93676.1 - 7.5e-05 22.6 0.0 0.00023 21.1 0.0 1.9 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 EAQ93676.1 - 0.0019 18.2 0.0 0.013 15.5 0.0 2.3 2 0 0 2 2 2 1 PAS fold PAS_3 PF08447.12 EAQ93676.1 - 0.0023 18.2 0.2 0.026 14.8 0.0 2.4 2 0 0 2 2 2 1 PAS fold GAF_2 PF13185.6 EAQ93676.1 - 0.0023 18.2 0.1 0.11 12.8 0.0 2.9 3 0 0 3 3 3 1 GAF domain GAF_3 PF13492.6 EAQ93676.1 - 0.029 14.7 0.0 0.065 13.6 0.0 1.6 1 0 0 1 1 1 0 GAF domain PH_6 PF15406.6 EAQ93677.1 - 2.6e-45 153.3 3.2 2.6e-45 153.3 3.2 3.4 4 1 1 5 5 5 1 Pleckstrin homology domain PH PF00169.29 EAQ93677.1 - 0.0064 17.0 0.0 0.017 15.6 0.0 1.9 1 0 0 1 1 1 1 PH domain IQ_SEC7_PH PF16453.5 EAQ93677.1 - 0.18 11.7 0.0 0.33 10.9 0.0 1.4 1 0 0 1 1 1 0 PH domain RNA_pol_Rpc4 PF05132.14 EAQ93678.1 - 1.3 9.5 8.8 4.1 7.8 0.1 2.4 2 0 0 2 2 2 0 RNA polymerase III RPC4 tRNA-synt_2 PF00152.20 EAQ93679.1 - 1.6e-59 201.5 0.0 7.5e-59 199.3 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EAQ93679.1 - 5.5e-11 42.3 0.0 9.9e-11 41.5 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EAQ93679.1 - 0.00038 20.0 0.0 0.04 13.4 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) zf-Tim10_DDP PF02953.15 EAQ93680.1 - 3.1e-16 58.8 2.5 3.5e-16 58.6 2.5 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.13 EAQ93680.1 - 0.014 15.1 2.3 0.02 14.6 2.3 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) PG_binding_1 PF01471.18 EAQ93681.1 - 0.0047 17.1 0.0 1.6 9.0 0.0 2.7 2 0 0 2 2 2 2 Putative peptidoglycan binding domain Tropomyosin_1 PF12718.7 EAQ93681.1 - 0.053 13.7 2.9 0.081 13.1 0.2 2.4 1 1 1 2 2 2 0 Tropomyosin like DUF410 PF04190.13 EAQ93681.1 - 0.093 12.5 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF410) Spc7 PF08317.11 EAQ93681.1 - 0.13 11.1 2.1 0.21 10.5 2.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein APG6_N PF17675.1 EAQ93681.1 - 0.37 11.3 3.0 1 9.9 3.0 1.7 1 0 0 1 1 1 0 Apg6 coiled-coil region NPV_P10 PF05531.12 EAQ93681.1 - 0.39 11.2 1.1 29 5.2 0.1 2.7 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein SlyX PF04102.12 EAQ93681.1 - 0.9 10.2 5.9 10 6.8 0.5 3.0 2 0 0 2 2 2 0 SlyX CLTH PF10607.9 EAQ93682.1 - 2.8e-30 105.1 0.0 3.8e-30 104.7 0.0 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain CRPA PF05745.11 EAQ93683.1 - 0.039 14.0 0.8 2.8 7.9 0.1 2.6 2 0 0 2 2 2 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) PPP4R2 PF09184.11 EAQ93684.1 - 7.1e-05 22.5 21.0 0.25 10.9 21.0 3.3 1 1 0 1 1 1 1 PPP4R2 AAA_23 PF13476.6 EAQ93685.1 - 4.1e-34 118.8 0.1 4.1e-34 118.8 0.1 7.6 1 1 3 4 4 1 1 AAA domain AAA_15 PF13175.6 EAQ93685.1 - 1.3e-10 41.6 2.5 9.7e-07 28.8 1.8 5.7 2 1 3 5 5 4 2 AAA ATPase domain AAA_21 PF13304.6 EAQ93685.1 - 6.7e-09 36.0 0.7 9.4e-06 25.6 0.3 4.8 4 3 2 6 6 6 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EAQ93685.1 - 7.7e-09 35.3 32.3 1.6e-07 31.0 0.0 2.9 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 EAQ93685.1 - 5e-06 26.7 0.1 2.2e-05 24.6 0.0 2.2 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 EAQ93685.1 - 0.00083 19.0 0.0 0.0017 18.0 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF641 PF04859.12 EAQ93685.1 - 0.018 15.4 1.1 0.018 15.4 1.1 9.7 4 3 5 10 10 9 0 Plant protein of unknown function (DUF641) AAA_16 PF13191.6 EAQ93685.1 - 0.061 13.7 0.0 0.061 13.7 0.0 5.2 3 2 0 3 3 1 0 AAA ATPase domain ABC_tran PF00005.27 EAQ93685.1 - 0.066 13.7 0.0 0.066 13.7 0.0 7.1 3 2 0 4 4 2 0 ABC transporter Pesticin PF16754.5 EAQ93685.1 - 0.1 12.6 2.1 0.27 11.2 0.4 2.7 2 0 0 2 2 2 0 Bacterial toxin homologue of phage lysozyme, C-term AAA_13 PF13166.6 EAQ93685.1 - 0.14 10.8 0.0 0.14 10.8 0.0 7.0 3 1 4 7 7 7 0 AAA domain DUF3800 PF12686.7 EAQ93685.1 - 0.58 10.8 4.0 4.2e+02 1.6 3.6 4.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) AAA_22 PF13401.6 EAQ93685.1 - 8.6 6.6 11.1 3.4 8.0 0.0 4.1 3 1 0 3 3 3 0 AAA domain GATA PF00320.27 EAQ93687.1 - 7.7e-16 57.4 6.0 1.9e-15 56.2 6.0 1.7 1 0 0 1 1 1 1 GATA zinc finger PAS_3 PF08447.12 EAQ93687.1 - 8.1e-13 48.5 0.0 1.8e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 EAQ93687.1 - 3.6e-06 27.0 0.0 8.3e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_11 PF14598.6 EAQ93687.1 - 1.8e-05 24.8 0.0 3.9e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 EAQ93687.1 - 0.00027 21.1 0.0 0.00052 20.2 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 EAQ93687.1 - 0.00056 20.1 0.0 0.003 17.8 0.0 2.0 2 0 0 2 2 2 1 PAS domain Zn-ribbon_8 PF09723.10 EAQ93687.1 - 0.0029 17.7 0.2 0.0068 16.5 0.2 1.6 1 0 0 1 1 1 1 Zinc ribbon domain PRKG1_interact PF15898.5 EAQ93687.1 - 0.03 15.2 0.9 0.054 14.4 0.9 1.3 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain TF_Zn_Ribbon PF08271.12 EAQ93687.1 - 0.1 12.1 1.6 0.78 9.3 0.2 2.8 3 0 0 3 3 3 0 TFIIB zinc-binding PAS_8 PF13188.7 EAQ93687.1 - 0.13 12.3 0.0 0.34 11.0 0.0 1.7 1 0 0 1 1 1 0 PAS domain LapA_dom PF06305.11 EAQ93687.1 - 1.8 8.4 4.1 0.5 10.2 1.1 1.6 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain adh_short PF00106.25 EAQ93688.1 - 1.7e-29 102.7 0.1 1.3e-28 99.9 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EAQ93688.1 - 2.6e-19 69.7 0.0 4.4e-19 69.0 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EAQ93688.1 - 4.5e-08 33.2 0.1 4.2e-07 30.0 0.1 2.1 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EAQ93688.1 - 4.7e-05 23.3 0.0 9.1e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding NACHT PF05729.12 EAQ93689.1 - 2.8e-09 37.1 0.0 5.6e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EAQ93689.1 - 5.5e-08 33.4 0.2 3.8e-06 27.4 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 EAQ93689.1 - 0.016 14.4 0.0 0.03 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) NB-ARC PF00931.22 EAQ93689.1 - 0.045 12.9 0.0 0.13 11.4 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain AAA_30 PF13604.6 EAQ93689.1 - 0.073 12.8 0.0 0.45 10.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.14 EAQ93689.1 - 0.077 12.2 0.1 0.18 11.0 0.1 1.5 1 0 0 1 1 1 0 KAP family P-loop domain CbiA PF01656.23 EAQ93689.1 - 0.083 12.9 1.2 0.63 10.1 0.2 2.7 3 0 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain APS_kinase PF01583.20 EAQ93689.1 - 0.16 11.8 0.1 0.36 10.7 0.1 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase FAD-oxidase_C PF02913.19 EAQ93690.1 - 5.7e-64 216.1 0.2 8.7e-64 215.5 0.2 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 EAQ93690.1 - 7.2e-38 129.5 0.1 3e-37 127.4 0.0 2.1 3 0 0 3 3 3 1 FAD binding domain Clr5 PF14420.6 EAQ93691.1 - 9.1e-09 35.4 1.9 3.9e-08 33.4 1.5 2.2 2 1 0 2 2 1 1 Clr5 domain TFIIA PF03153.13 EAQ93691.1 - 6.3e-05 23.1 38.8 6.3e-05 23.1 38.8 2.0 3 0 0 3 3 2 1 Transcription factor IIA, alpha/beta subunit SOG2 PF10428.9 EAQ93691.1 - 0.033 13.4 16.3 0.049 12.8 16.3 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein EPL1 PF10513.9 EAQ93691.1 - 0.035 14.5 6.0 0.078 13.4 6.0 1.6 1 0 0 1 1 1 0 Enhancer of polycomb-like HTH_21 PF13276.6 EAQ93691.1 - 0.049 13.8 0.3 0.28 11.3 0.2 2.3 2 0 0 2 2 2 0 HTH-like domain SpoIIP PF07454.11 EAQ93691.1 - 0.12 11.8 7.3 0.28 10.6 7.3 1.5 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Mlh1_C PF16413.5 EAQ93691.1 - 0.18 11.1 8.0 0.35 10.2 8.0 1.4 1 0 0 1 1 1 0 DNA mismatch repair protein Mlh1 C-terminus DUF2722 PF10846.8 EAQ93691.1 - 0.19 10.6 27.0 0.016 14.2 20.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) TERB2 PF15101.6 EAQ93691.1 - 0.29 11.2 10.4 0.52 10.3 10.4 1.4 1 0 0 1 1 1 0 Telomere-associated protein TERB2 eIF-3_zeta PF05091.12 EAQ93691.1 - 0.72 8.8 13.5 1.1 8.2 13.5 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Connexin PF00029.19 EAQ93691.1 - 0.78 9.5 3.4 1.2 8.8 3.4 1.2 1 0 0 1 1 1 0 Connexin EIIBC-GUT_N PF03612.14 EAQ93691.1 - 0.97 9.1 7.2 2.1 8.1 7.2 1.5 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus CLN3 PF02487.17 EAQ93691.1 - 1.1 8.3 3.2 1.5 7.8 3.2 1.1 1 0 0 1 1 1 0 CLN3 protein DUF4407 PF14362.6 EAQ93691.1 - 1.1 8.5 7.6 2 7.7 7.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3391 PF11871.8 EAQ93691.1 - 1.4 9.4 14.4 0.28 11.7 6.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) OATP PF03137.20 EAQ93691.1 - 1.9 6.7 3.0 2.7 6.2 3.0 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family V_ATPase_I PF01496.19 EAQ93691.1 - 2.2 6.1 6.3 3.2 5.6 6.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF5308 PF17233.2 EAQ93691.1 - 2.2 8.5 16.8 0.19 11.9 10.9 2.0 1 1 0 2 2 2 0 Family of unknown function (DUF5308) ZYG-11_interact PF05884.12 EAQ93691.1 - 2.4 7.5 5.7 3.6 6.9 5.7 1.2 1 0 0 1 1 1 0 Interactor of ZYG-11 PAT1 PF09770.9 EAQ93691.1 - 2.4 6.3 27.0 3.7 5.7 27.0 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Coilin_N PF15862.5 EAQ93691.1 - 2.8 7.7 12.6 19 5.1 11.3 2.4 2 0 0 2 2 2 0 Coilin N-terminus EMC3_TMCO1 PF01956.16 EAQ93691.1 - 4 7.1 8.1 7.1 6.3 8.1 1.3 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like CDT1_C PF16679.5 EAQ93691.1 - 4 7.9 0.0 4 7.9 0.0 2.8 2 0 0 2 2 2 0 DNA replication factor Cdt1 C-terminal domain DUF4518 PF15008.6 EAQ93691.1 - 5.7 6.0 13.1 35 3.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4518) TPR_10 PF13374.6 EAQ93692.1 - 9.8e-20 69.8 0.2 7e-07 28.9 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 EAQ93692.1 - 5.6e-14 52.2 1.3 2.2e-08 34.3 0.1 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_MalT PF17874.1 EAQ93692.1 - 0.0015 18.0 0.6 0.013 14.9 0.0 2.0 1 1 1 2 2 2 1 MalT-like TPR region TPR_7 PF13176.6 EAQ93692.1 - 0.04 13.9 0.4 5 7.4 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat PRCC PF10253.9 EAQ93692.1 - 0.065 14.0 2.7 0.27 12.0 0.9 2.4 2 1 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting TPR_2 PF07719.17 EAQ93692.1 - 0.086 13.0 1.6 2.9 8.2 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF4574 PF15141.6 EAQ93692.1 - 0.61 10.0 2.8 0.86 9.6 0.8 2.1 2 0 0 2 2 2 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 Amidase PF01425.21 EAQ93693.1 - 7.6e-65 219.6 0.0 1.1e-64 219.1 0.0 1.1 1 0 0 1 1 1 1 Amidase BASP1 PF05466.12 EAQ93694.1 - 0.026 14.5 1.0 0.055 13.5 1.0 1.4 1 0 0 1 1 1 0 Brain acid soluble protein 1 (BASP1 protein) Troponin PF00992.20 EAQ93694.1 - 1.6 9.0 11.8 2.8 8.2 0.0 2.3 2 0 0 2 2 2 0 Troponin Glyco_tranf_2_3 PF13641.6 EAQ93697.1 - 2.7e-18 66.7 0.2 3.7e-18 66.3 0.2 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 EAQ93697.1 - 4.2e-05 23.1 0.0 8.6e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 EAQ93697.1 - 0.017 14.9 0.1 0.056 13.3 0.0 1.9 2 0 0 2 2 2 0 Glycosyl transferase family 2 SOG2 PF10428.9 EAQ93699.1 - 8.9 5.4 14.9 12 4.9 14.9 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein GWT1 PF06423.12 EAQ93701.1 - 2.3e-42 144.6 0.2 5.6e-42 143.4 0.2 1.7 1 0 0 1 1 1 1 GWT1 DUF4818 PF16089.5 EAQ93701.1 - 0.00051 20.5 0.2 0.0022 18.5 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4818) Pkinase PF00069.25 EAQ93702.1 - 7.6e-64 215.6 0.0 2.4e-63 214.0 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAQ93702.1 - 7.1e-36 123.8 0.0 3.2e-30 105.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EAQ93702.1 - 5.6e-07 29.2 0.1 0.0012 18.2 0.0 2.2 1 1 0 2 2 2 2 Kinase-like APH PF01636.23 EAQ93702.1 - 6.7e-06 26.2 0.1 3.7e-05 23.8 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EAQ93702.1 - 0.0067 15.8 0.1 0.014 14.8 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EAQ93702.1 - 0.012 14.6 0.1 0.019 13.9 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain RIO1 PF01163.22 EAQ93702.1 - 0.045 13.4 0.0 0.086 12.4 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 EAQ93702.1 - 0.55 8.9 2.4 0.82 8.4 0.0 2.1 2 0 0 2 2 2 0 Fungal protein kinase RRM_1 PF00076.22 EAQ93703.1 - 6.1e-15 54.8 0.1 1.4e-14 53.6 0.1 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 EAQ93703.1 - 0.0024 17.9 0.1 0.0042 17.1 0.1 1.4 1 0 0 1 1 1 1 RNA binding motif RRM_5 PF13893.6 EAQ93703.1 - 0.1 12.2 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glyco_hydro_76 PF03663.14 EAQ93704.1 - 3.1e-19 69.7 5.1 1e-11 45.0 0.2 3.9 3 1 0 3 3 3 2 Glycosyl hydrolase family 76 ADK PF00406.22 EAQ93705.1 - 4.2e-20 72.4 0.0 2.9e-14 53.4 0.0 2.1 2 0 0 2 2 2 2 Adenylate kinase ADK_lid PF05191.14 EAQ93705.1 - 1e-13 51.0 0.0 1.8e-13 50.2 0.0 1.5 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.6 EAQ93705.1 - 0.0074 16.7 0.0 0.076 13.4 0.0 2.2 1 1 0 2 2 2 1 AAA domain LETM1 PF07766.13 EAQ93706.1 - 3.3e-106 354.5 0.4 3.3e-106 354.5 0.4 1.4 2 0 0 2 2 2 1 LETM1-like protein SAP PF02037.27 EAQ93706.1 - 0.00082 19.1 0.0 0.17 11.7 0.0 3.4 3 0 0 3 3 3 1 SAP domain BPL_N PF09825.9 EAQ93706.1 - 2.7 7.0 5.9 0.53 9.3 0.1 2.1 2 0 0 2 2 2 0 Biotin-protein ligase, N terminal PX PF00787.24 EAQ93707.1 - 4.5e-20 71.7 0.1 1.2e-19 70.4 0.1 1.7 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 EAQ93707.1 - 5.7e-09 35.9 8.0 4.3e-06 26.4 1.9 2.1 2 0 0 2 2 2 2 Vps5 C terminal like BAR PF03114.18 EAQ93707.1 - 2.2e-07 30.8 3.9 0.0042 16.8 2.2 2.2 2 0 0 2 2 2 2 BAR domain Sec34 PF04136.15 EAQ93707.1 - 0.014 15.3 0.7 0.026 14.4 0.3 1.6 1 1 0 1 1 1 0 Sec34-like family DUF4795 PF16043.5 EAQ93707.1 - 0.05 13.2 2.3 0.24 11.0 2.6 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) BAR_3 PF16746.5 EAQ93707.1 - 0.088 12.5 2.4 6.8 6.3 0.1 2.7 2 1 0 3 3 3 0 BAR domain of APPL family Laminin_II PF06009.12 EAQ93707.1 - 0.15 12.1 3.4 0.079 13.0 0.8 1.9 2 1 0 2 2 2 0 Laminin Domain II FlaC_arch PF05377.11 EAQ93707.1 - 0.79 10.2 3.1 1.2 9.6 1.1 2.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Leu_zip PF15294.6 EAQ93707.1 - 1 8.8 6.6 0.39 10.2 3.7 1.6 2 0 0 2 2 2 0 Leucine zipper XhlA PF10779.9 EAQ93707.1 - 1.4 9.2 4.9 0.36 11.1 1.0 2.0 2 0 0 2 2 2 0 Haemolysin XhlA SHE3 PF17078.5 EAQ93707.1 - 2.3 7.9 6.5 1.1 9.0 2.8 2.0 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 Spc7 PF08317.11 EAQ93707.1 - 4.9 5.9 10.3 0.27 10.1 4.1 2.0 2 1 0 2 2 2 0 Spc7 kinetochore protein DUF16 PF01519.16 EAQ93707.1 - 7.3 7.1 6.9 1.1 9.8 1.1 2.4 2 1 1 3 3 3 0 Protein of unknown function DUF16 eIF3_subunit PF08597.10 EAQ93707.1 - 8.1 6.3 11.0 0.25 11.2 3.6 1.9 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit Peptidase_S8 PF00082.22 EAQ93708.1 - 4e-39 134.7 1.6 4e-39 134.7 1.6 1.8 2 0 0 2 2 2 1 Subtilase family P_proprotein PF01483.20 EAQ93708.1 - 2.2e-24 85.3 1.1 4.4e-24 84.3 1.1 1.5 1 0 0 1 1 1 1 Proprotein convertase P-domain Peptidase_S8_N PF16361.5 EAQ93708.1 - 0.019 15.5 0.0 0.054 14.0 0.0 1.7 2 0 0 2 2 2 0 N-terminal of Subtilase family S8_pro-domain PF16470.5 EAQ93708.1 - 0.019 15.7 0.1 0.05 14.4 0.1 1.7 1 0 0 1 1 1 0 Peptidase S8 pro-domain PhoD PF09423.10 EAQ93709.1 - 0.0008 18.5 0.0 0.023 13.7 0.0 2.2 2 0 0 2 2 2 2 PhoD-like phosphatase Na_Ca_ex PF01699.24 EAQ93710.1 - 1.1e-32 113.1 31.8 1.7e-21 76.8 20.2 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein KIAA1328 PF15369.6 EAQ93710.1 - 3 7.6 8.1 4.5 7.0 8.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein KIAA1328 SPRY PF00622.28 EAQ93711.1 - 3.3e-05 24.0 0.0 5.1e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 SPRY domain DEAD PF00270.29 EAQ93712.1 - 6.6e-28 97.7 0.0 1.1e-15 57.9 0.0 2.3 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 EAQ93712.1 - 5e-23 81.6 0.0 1.3e-22 80.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EAQ93712.1 - 1.5e-05 25.0 0.4 0.0002 21.4 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit TRAP_alpha PF03896.16 EAQ93712.1 - 7.4 5.7 7.9 7.3 5.7 0.1 2.9 3 0 0 3 3 3 0 Translocon-associated protein (TRAP), alpha subunit tRNA-synt_1 PF00133.22 EAQ93713.1 - 1.4e-148 495.8 0.0 1.9e-148 495.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 EAQ93713.1 - 2.9e-19 69.1 0.0 2e-11 43.3 0.0 3.3 3 0 0 3 3 3 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 EAQ93713.1 - 4.8e-18 65.6 0.0 8.5e-18 64.8 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 EAQ93713.1 - 0.015 14.6 0.1 0.45 9.8 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain DUF35_N PF12172.8 EAQ93713.1 - 0.2 11.6 10.4 0.023 14.5 4.0 2.7 3 0 0 3 3 3 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Tom37 PF10568.9 EAQ93714.1 - 5e-32 110.8 3.5 7.4e-32 110.3 3.5 1.3 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_6 PF17171.4 EAQ93714.1 - 0.00021 21.0 0.0 0.00046 19.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 EAQ93714.1 - 0.097 13.4 0.1 0.53 11.1 0.1 2.2 2 1 0 2 2 2 0 Glutathione S-transferase N-terminal domain K_channel_TID PF07941.11 EAQ93714.1 - 0.75 10.3 6.7 1 9.9 5.6 1.8 1 1 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain PIG-U PF06728.13 EAQ93717.1 - 1.8e-84 284.0 23.7 2.2e-84 283.7 23.7 1.1 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U BatA PF07584.11 EAQ93717.1 - 0.06 13.7 2.0 0.24 11.8 0.2 2.8 2 0 0 2 2 2 0 Aerotolerance regulator N-terminal 8TM_micro PF17028.5 EAQ93717.1 - 0.16 11.6 7.9 0.41 10.3 7.8 1.6 1 1 0 1 1 1 0 8TM Microsporidial transmembrane domain Pescadillo_N PF06732.11 EAQ93718.1 - 1e-121 405.7 0.0 1e-121 405.7 0.0 1.6 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT PF00533.26 EAQ93718.1 - 0.0026 18.1 0.0 0.016 15.6 0.0 2.2 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Astro_capsid_p PF12226.8 EAQ93718.1 - 0.0058 15.8 10.6 0.0058 15.8 10.6 1.6 2 0 0 2 2 2 1 Turkey astrovirus capsid protein BRCT_2 PF16589.5 EAQ93718.1 - 0.017 15.5 0.0 0.072 13.5 0.0 2.1 1 1 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain RRN9 PF10680.9 EAQ93719.1 - 1.1e-21 76.8 0.0 3.8e-20 71.9 0.0 3.2 3 0 0 3 3 3 1 RNA polymerase I specific transcription initiation factor Kinesin PF00225.23 EAQ93720.1 - 2.7e-111 371.7 1.0 2.7e-111 371.7 1.0 2.3 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EAQ93720.1 - 1.7e-25 89.7 0.1 1.7e-25 89.7 0.1 2.7 4 0 0 4 4 4 1 Microtubule binding Microtub_bind PF13931.6 EAQ93720.1 - 2.1e-05 24.9 0.6 2.1e-05 24.9 0.6 5.6 3 1 2 5 5 5 1 Kinesin-associated microtubule-binding UPF0183 PF03676.14 EAQ93721.1 - 4.5e-52 177.7 0.0 4.9e-31 108.4 0.0 3.8 3 1 0 3 3 3 3 Uncharacterised protein family (UPF0183) LRR_RI_capping PF18779.1 EAQ93721.1 - 0.17 11.5 0.0 0.37 10.5 0.0 1.5 1 0 0 1 1 1 0 Capping Ribonuclease inhibitor Leucine Rich Repeat Syja_N PF02383.18 EAQ93723.1 - 5.5e-90 301.9 0.0 6.9e-90 301.6 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain Ras PF00071.22 EAQ93724.1 - 1.1e-46 158.4 4.4 2.6e-41 140.9 1.6 2.0 1 1 1 2 2 2 2 Ras family Roc PF08477.13 EAQ93724.1 - 1.3e-26 93.2 2.2 1.3e-20 73.8 0.5 2.5 2 1 1 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAQ93724.1 - 2.8e-12 46.4 0.3 3.7e-11 42.8 0.3 1.9 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EAQ93724.1 - 5.3e-07 29.4 0.1 6.8e-07 29.0 0.1 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EAQ93724.1 - 6.9e-06 26.1 2.1 0.024 14.6 0.4 2.3 1 1 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 EAQ93724.1 - 4e-05 23.1 0.6 0.00056 19.3 0.6 2.0 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EAQ93724.1 - 0.0015 18.6 0.4 0.18 11.9 0.4 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 EAQ93724.1 - 0.0085 16.5 0.1 0.012 16.0 0.1 1.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EAQ93724.1 - 0.09 13.1 0.0 2.9 8.2 0.0 2.2 1 1 1 2 2 2 0 AAA domain PRK PF00485.18 EAQ93724.1 - 0.1 12.3 0.0 0.14 11.9 0.0 1.3 1 1 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Mitofilin PF09731.9 EAQ93725.1 - 3.1e-169 564.8 11.4 4.4e-169 564.3 11.4 1.2 1 0 0 1 1 1 1 Mitochondrial inner membrane protein YceG_bac PF14266.6 EAQ93725.1 - 0.041 12.8 1.8 0.061 12.2 1.8 1.1 1 0 0 1 1 1 0 Putative component of 'biosynthetic module' 4HB_MCP_1 PF12729.7 EAQ93725.1 - 0.13 11.8 8.4 0.29 10.7 8.4 1.5 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction Mur_ligase_M PF08245.12 EAQ93726.1 - 0.019 15.0 0.8 0.13 12.2 0.8 2.4 1 1 0 1 1 1 0 Mur ligase middle domain ACC_epsilon PF13822.6 EAQ93726.1 - 0.081 13.6 0.4 0.32 11.7 0.4 2.1 1 0 0 1 1 1 0 Acyl-CoA carboxylase epsilon subunit Mur_ligase_C PF02875.21 EAQ93726.1 - 0.094 13.0 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain Mur_ligase_C PF02875.21 EAQ93727.1 - 0.018 15.3 0.0 0.056 13.7 0.0 1.9 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain DUF1479 PF07350.12 EAQ93727.1 - 0.19 10.5 0.4 0.32 9.7 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1479) ADH_N PF08240.12 EAQ93728.1 - 1.3e-28 99.1 0.8 2.5e-28 98.1 0.1 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EAQ93728.1 - 8.2e-23 80.8 1.4 8.2e-23 80.8 1.4 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EAQ93728.1 - 1.8e-08 34.2 1.2 3.1e-08 33.4 1.2 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 EAQ93728.1 - 8.6e-08 33.3 0.1 2.5e-07 31.8 0.1 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.14 EAQ93728.1 - 0.008 15.8 0.7 0.036 13.6 0.2 2.0 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_25 PF13649.6 EAQ93728.1 - 0.038 14.7 0.1 0.075 13.7 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase domain AlaDh_PNT_C PF01262.21 EAQ93728.1 - 0.055 12.8 2.5 0.086 12.1 2.5 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain AdoHcyase_NAD PF00670.21 EAQ93728.1 - 0.062 13.4 0.5 2.3 8.3 0.7 2.2 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Pyr_redox_3 PF13738.6 EAQ93728.1 - 0.079 12.2 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Mannosidase_ig PF17786.1 EAQ93729.1 - 1.3e-12 48.2 1.4 2.3e-12 47.3 0.1 2.1 2 0 0 2 2 2 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 EAQ93729.1 - 4.8e-12 46.5 0.1 1.1e-11 45.3 0.1 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Ig_mannosidase PF17753.1 EAQ93729.1 - 3.6e-06 26.6 0.0 1e-05 25.1 0.0 1.8 1 0 0 1 1 1 1 Ig-fold domain Glyco_hydro_2_C PF02836.17 EAQ93729.1 - 0.012 14.8 0.2 0.044 12.9 0.2 1.8 1 1 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.18 EAQ93729.1 - 0.059 13.3 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, sugar binding domain Ras PF00071.22 EAQ93730.1 - 9.9e-42 142.3 0.0 1.5e-41 141.7 0.0 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAQ93730.1 - 5.3e-29 100.9 0.0 8e-29 100.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAQ93730.1 - 1.1e-11 44.5 0.0 5e-11 42.4 0.0 1.8 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EAQ93730.1 - 2.7e-05 24.2 0.0 4.2e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EAQ93730.1 - 0.0017 17.7 0.0 0.0023 17.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_33 PF13671.6 EAQ93730.1 - 0.002 18.3 0.0 0.0031 17.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain SRPRB PF09439.10 EAQ93730.1 - 0.0036 16.8 0.0 0.0047 16.4 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 EAQ93730.1 - 0.0059 16.9 0.1 0.016 15.5 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 EAQ93730.1 - 0.035 13.6 0.0 0.054 13.0 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region RsgA_GTPase PF03193.16 EAQ93730.1 - 0.037 13.9 0.0 0.087 12.7 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_28 PF13521.6 EAQ93730.1 - 0.064 13.5 0.0 0.097 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EAQ93730.1 - 0.072 13.5 0.1 0.23 11.8 0.1 1.7 2 1 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.27 EAQ93730.1 - 0.11 13.0 0.0 0.19 12.2 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_5 PF07728.14 EAQ93730.1 - 0.15 12.0 0.0 0.33 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 EAQ93730.1 - 0.16 11.9 0.0 0.26 11.2 0.0 1.3 1 0 0 1 1 1 0 NACHT domain adh_short PF00106.25 EAQ93731.1 - 4.1e-23 81.9 0.1 7.9e-17 61.4 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EAQ93731.1 - 2.7e-16 59.9 0.1 2.9e-13 49.9 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EAQ93731.1 - 5.1e-05 23.3 1.1 0.056 13.4 0.0 2.3 2 0 0 2 2 2 2 KR domain 2-Hacid_dh_C PF02826.19 EAQ93733.1 - 2.3e-44 150.8 0.1 1.3e-43 148.5 0.1 2.0 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EAQ93733.1 - 2.9e-05 23.8 0.0 4e-05 23.3 0.0 1.3 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AOC_like PF18678.1 EAQ93733.1 - 0.055 13.1 0.2 0.12 12.0 0.2 1.5 1 0 0 1 1 1 0 Allene oxide cyclase barrel like domain DUF1749 PF08538.10 EAQ93734.1 - 2.5e-53 181.1 0.0 3.3e-53 180.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_1 PF00561.20 EAQ93734.1 - 0.021 14.5 0.0 0.028 14.1 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold RNase_T PF00929.24 EAQ93736.1 - 0.0063 17.1 0.0 0.091 13.3 0.0 2.4 1 1 0 1 1 1 1 Exonuclease GRDP-like PF07173.12 EAQ93738.1 - 4.5e-19 69.5 0.0 3.3e-16 60.2 0.0 2.3 2 0 0 2 2 2 2 Glycine-rich domain-containing protein-like Lipase_3 PF01764.25 EAQ93739.1 - 5.7e-11 42.5 0.0 1e-10 41.6 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Peptidase_S9 PF00326.21 EAQ93740.1 - 8.5e-48 162.6 2.7 9.4e-48 162.5 1.6 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family DPPIV_N PF00930.21 EAQ93740.1 - 3.8e-34 118.0 0.8 2.4e-33 115.4 0.8 2.0 1 1 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region VHL PF01847.16 EAQ93740.1 - 2.6e-09 36.9 0.0 8.6e-09 35.2 0.0 1.9 1 0 0 1 1 1 1 VHL beta domain Peptidase_S15 PF02129.18 EAQ93740.1 - 2.3e-05 24.1 2.6 0.0014 18.3 2.3 2.3 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.18 EAQ93740.1 - 0.00077 19.1 0.0 0.0015 18.1 0.0 1.4 1 0 0 1 1 1 1 Dienelactone hydrolase family Esterase PF00756.20 EAQ93740.1 - 0.0016 18.2 0.6 0.0035 17.0 0.6 1.5 1 0 0 1 1 1 1 Putative esterase Esterase_phd PF10503.9 EAQ93740.1 - 0.038 13.5 1.4 0.062 12.8 1.4 1.2 1 0 0 1 1 1 0 Esterase PHB depolymerase Abhydrolase_3 PF07859.13 EAQ93740.1 - 0.43 10.4 3.1 9.9 5.9 3.1 2.3 1 1 0 1 1 1 0 alpha/beta hydrolase fold Zn_Tnp_IS1595 PF12760.7 EAQ93741.1 - 1.8 8.6 6.1 0.3 11.1 1.3 2.1 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Glyco_hydro_11 PF00457.17 EAQ93743.1 - 3.5e-65 219.0 9.4 4.3e-65 218.7 9.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 YppG PF14179.6 EAQ93744.1 - 0.14 12.8 5.2 0.2 12.3 5.2 1.2 1 0 0 1 1 1 0 YppG-like protein Dicty_REP PF05086.12 EAQ93744.1 - 3.2 5.6 7.1 3.5 5.5 7.1 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Dynamitin PF04912.14 EAQ93745.1 - 0.00087 18.7 5.6 0.0012 18.2 5.6 1.2 1 0 0 1 1 1 1 Dynamitin NCA2 PF08637.10 EAQ93745.1 - 0.037 13.2 0.5 0.054 12.7 0.5 1.1 1 0 0 1 1 1 0 ATP synthase regulation protein NCA2 FAM76 PF16046.5 EAQ93745.1 - 0.061 12.7 1.0 0.087 12.2 1.0 1.2 1 0 0 1 1 1 0 FAM76 protein Interferon PF00143.19 EAQ93745.1 - 0.077 13.2 0.2 0.39 10.9 0.3 1.9 2 0 0 2 2 2 0 Interferon alpha/beta domain DrsE PF02635.15 EAQ93745.1 - 0.1 13.0 0.0 3 8.2 0.0 2.7 2 0 0 2 2 2 0 DsrE/DsrF-like family FlgN PF05130.12 EAQ93745.1 - 0.22 12.0 7.8 0.37 11.3 7.8 1.3 1 0 0 1 1 1 0 FlgN protein Allexi_40kDa PF05549.11 EAQ93745.1 - 0.32 10.5 1.5 0.46 10.0 1.5 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein DUF2894 PF11445.8 EAQ93745.1 - 1.1 9.7 11.6 2.5 8.5 11.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2894) ECH_1 PF00378.20 EAQ93746.1 - 5.5e-10 39.0 0.4 1.4e-05 24.6 0.0 2.1 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EAQ93746.1 - 0.16 11.5 0.1 0.37 10.2 0.0 1.4 1 1 1 2 2 2 0 Enoyl-CoA hydratase/isomerase AMP-binding PF00501.28 EAQ93747.1 - 2.6e-49 168.0 8.3 6.3e-28 97.5 1.3 3.2 2 1 1 3 3 3 3 AMP-binding enzyme AMP-binding_C PF13193.6 EAQ93747.1 - 0.00039 21.3 0.0 0.0016 19.4 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain MAM PF00629.23 EAQ93748.1 - 0.073 13.0 0.2 0.14 12.1 0.2 1.4 1 0 0 1 1 1 0 MAM domain, meprin/A5/mu Ferritin_2 PF13668.6 EAQ93749.1 - 1.7e-15 57.4 0.0 2.4e-15 56.9 0.0 1.3 1 0 0 1 1 1 1 Ferritin-like domain DUF1996 PF09362.10 EAQ93751.1 - 3.1e-80 269.5 2.2 3.8e-80 269.2 2.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Ank_2 PF12796.7 EAQ93754.1 - 3.4e-78 258.3 7.7 3.1e-10 40.5 0.0 10.4 4 2 6 12 12 12 11 Ankyrin repeats (3 copies) Ank PF00023.30 EAQ93754.1 - 2.7e-53 176.2 47.8 0.00048 20.5 1.7 18.3 18 1 1 19 19 19 14 Ankyrin repeat Ank_4 PF13637.6 EAQ93754.1 - 1.9e-50 168.6 9.7 9.9e-08 32.4 0.0 15.0 6 5 10 16 16 16 14 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAQ93754.1 - 7.2e-48 155.0 19.9 0.028 15.0 0.0 18.4 19 1 0 19 19 19 13 Ankyrin repeat Ank_5 PF13857.6 EAQ93754.1 - 3.8e-36 122.7 29.6 1.4e-06 28.4 0.1 14.6 9 5 8 17 17 17 12 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAQ93755.1 - 3e-12 47.0 0.3 3.5e-05 24.3 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAQ93755.1 - 1.7e-06 28.2 1.1 0.3 11.4 0.0 4.9 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAQ93755.1 - 3.8e-05 24.1 0.8 1.4 9.6 0.0 3.9 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAQ93755.1 - 4.5e-05 23.5 4.5 0.12 13.0 0.0 5.3 5 0 0 5 5 5 1 Ankyrin repeat Ank PF00023.30 EAQ93755.1 - 0.00016 22.0 0.9 0.024 15.1 0.1 3.6 3 0 0 3 3 3 1 Ankyrin repeat Peptidase_S8 PF00082.22 EAQ93755.1 - 0.012 14.9 0.1 0.039 13.2 0.1 1.7 1 1 0 1 1 1 0 Subtilase family DUF2520 PF10728.9 EAQ93755.1 - 0.021 14.6 0.2 0.045 13.5 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2520) HET PF06985.11 EAQ93756.1 - 7e-15 55.7 0.0 1.3e-14 54.7 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) OrsD PF12013.8 EAQ93756.1 - 0.14 12.6 3.1 9 6.8 0.4 2.4 2 0 0 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D SWI-SNF_Ssr4 PF08549.10 EAQ93757.1 - 0.24 10.0 0.8 0.32 9.6 0.8 1.2 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) Fungal_trans_2 PF11951.8 EAQ93762.1 - 5.5e-29 101.2 0.0 6.7e-29 100.9 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain PAD PF03068.15 EAQ93763.1 - 1.5e-99 333.7 0.0 2.3e-99 333.0 0.0 1.1 1 0 0 1 1 1 1 Protein-arginine deiminase (PAD) DLH PF01738.18 EAQ93765.1 - 3e-09 36.8 0.0 0.0025 17.4 0.0 3.0 2 1 0 2 2 2 2 Dienelactone hydrolase family Ncstrn_small PF18266.1 EAQ93766.1 - 0.022 14.8 0.0 0.04 13.9 0.0 1.4 1 0 0 1 1 1 0 Nicastrin small lobe NAD_binding_1 PF00175.21 EAQ93767.1 - 1e-29 103.3 0.0 1.6e-29 102.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 EAQ93767.1 - 2.1e-23 82.5 0.0 3.9e-23 81.7 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.28 EAQ93767.1 - 1.2e-19 70.3 0.0 2.5e-19 69.2 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 EAQ93767.1 - 0.00047 20.3 0.0 0.067 13.3 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain p450 PF00067.22 EAQ93768.1 - 8.2e-69 232.5 0.0 9.6e-69 232.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 dCMP_cyt_deam_2 PF08211.12 EAQ93768.1 - 0.19 11.9 0.0 33 4.7 0.0 2.5 2 0 0 2 2 2 0 Cytidine and deoxycytidylate deaminase zinc-binding region Vip3A_N PF12495.8 EAQ93769.1 - 0.15 11.9 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 Vegetative insecticide protein 3A N terminal Glyco_hydro_127 PF07944.12 EAQ93770.1 - 8e-137 456.9 0.2 9.3e-137 456.6 0.2 1.0 1 0 0 1 1 1 1 Beta-L-arabinofuranosidase, GH127 DNA_pol_phi PF04931.13 EAQ93772.1 - 0.016 13.3 0.5 0.022 12.9 0.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi CAP_N PF01213.19 EAQ93772.1 - 0.92 8.9 7.6 0.06 12.8 1.6 1.8 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal DUF4407 PF14362.6 EAQ93772.1 - 4.6 6.5 6.3 8.9 5.6 6.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Pkinase PF00069.25 EAQ93774.1 - 1.2e-08 34.6 0.0 0.00014 21.4 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain SR-25 PF10500.9 EAQ93774.1 - 0.064 12.9 3.7 0.11 12.1 3.7 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Pkinase_Tyr PF07714.17 EAQ93774.1 - 0.13 11.5 0.0 0.69 9.1 0.0 1.9 2 0 0 2 2 2 0 Protein tyrosine kinase Aldo_ket_red PF00248.21 EAQ93776.1 - 2.3e-63 214.1 0.0 2.9e-63 213.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family CODH_A_N PF18537.1 EAQ93776.1 - 0.15 12.1 2.0 9.2 6.4 0.1 2.8 3 1 0 3 3 3 0 Carbon monoxide dehydrogenase subunit alpha N-terminal domain Astro_capsid_p PF12226.8 EAQ93781.1 - 0.19 10.9 2.7 0.24 10.5 2.7 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein zf-CRD PF17979.1 EAQ93781.1 - 0.29 11.2 0.5 20 5.3 0.1 2.1 2 0 0 2 2 2 0 Cysteine rich domain with multizinc binding regions Sporozoite_P67 PF05642.11 EAQ93781.1 - 0.67 8.0 4.5 0.87 7.6 4.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PHD_2 PF13831.6 EAQ93781.1 - 0.83 9.3 5.6 10 5.8 0.5 2.2 2 0 0 2 2 2 0 PHD-finger Zip PF02535.22 EAQ93783.1 - 5e-24 85.1 17.5 7.3e-14 51.7 2.9 3.6 3 1 2 5 5 5 3 ZIP Zinc transporter DnaJ PF00226.31 EAQ93784.1 - 3.7e-12 46.2 0.1 8.7e-12 45.0 0.1 1.6 1 0 0 1 1 1 1 DnaJ domain TFIIA PF03153.13 EAQ93784.1 - 0.025 14.6 9.7 0.032 14.2 9.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1943 PF09172.11 EAQ93784.1 - 0.86 8.8 4.2 1.4 8.1 4.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) DUF3138 PF11336.8 EAQ93784.1 - 2.3 6.7 8.5 3.3 6.2 8.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF2115 PF09888.9 EAQ93784.1 - 5.9 7.4 6.6 13 6.3 6.6 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2115) Fungal_trans PF04082.18 EAQ93785.1 - 1.7e-14 53.5 1.0 2.1e-14 53.2 0.1 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EAQ93785.1 - 1e-08 35.1 10.6 1.8e-08 34.4 10.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NUDIX PF00293.28 EAQ93786.1 - 6.9e-21 74.7 0.1 8.1e-21 74.4 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain cNMP_binding PF00027.29 EAQ93788.1 - 2.5e-34 117.2 0.0 3.4e-18 65.5 0.0 2.8 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain cNMPbd_u2 PF16643.5 EAQ93788.1 - 8.9e-28 97.7 8.2 8.9e-28 97.7 8.2 2.1 2 0 0 2 2 2 1 Unstructured region on cNMP-binding protein LRR_6 PF13516.6 EAQ93788.1 - 1.6e-07 30.8 0.2 0.72 10.1 0.0 5.2 5 0 0 5 5 5 2 Leucine Rich repeat F-box PF00646.33 EAQ93788.1 - 1.4e-06 28.0 3.5 1.6e-06 27.8 0.1 2.9 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.7 EAQ93788.1 - 5.9e-05 22.9 0.2 0.00023 21.0 0.2 2.1 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 EAQ93788.1 - 0.00021 21.6 0.0 1.2 9.7 0.0 4.1 1 1 4 5 5 5 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EAQ93788.1 - 0.012 16.0 4.5 46 5.1 0.0 5.9 7 1 0 7 7 7 0 Leucine Rich Repeat Bax1-I PF01027.20 EAQ93789.1 - 4.3e-36 124.7 9.5 6.8e-36 124.1 9.5 1.2 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Caprin-1_C PF12287.8 EAQ93789.1 - 0.083 13.0 0.5 0.12 12.5 0.5 1.1 1 0 0 1 1 1 0 Cytoplasmic activation/proliferation-associated protein-1 C term PMSR PF01625.21 EAQ93790.1 - 1e-59 201.1 0.1 1.2e-59 200.9 0.1 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase HET PF06985.11 EAQ93791.1 - 5.1e-33 114.5 1.0 9.6e-25 87.6 0.0 3.3 4 0 0 4 4 4 2 Heterokaryon incompatibility protein (HET) AAA PF00004.29 EAQ93792.1 - 4.2e-09 36.9 1.8 3.1e-06 27.6 1.8 2.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EAQ93792.1 - 0.019 15.3 7.4 0.15 12.4 0.1 3.4 4 1 1 5 5 5 0 AAA domain AAA_19 PF13245.6 EAQ93792.1 - 0.031 14.6 0.0 0.088 13.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EAQ93792.1 - 0.034 14.5 1.1 0.14 12.5 0.3 2.2 1 1 1 2 2 2 0 AAA ATPase domain Slx4 PF09494.10 EAQ93793.1 - 1.6e-21 76.0 0.0 6.7e-21 74.0 0.0 2.0 2 0 0 2 2 2 1 Slx4 endonuclease AT_hook PF02178.19 EAQ93793.1 - 3.1e-05 23.4 18.1 0.19 11.7 1.3 4.7 3 0 0 3 3 3 3 AT hook motif Ribosomal_S21e PF01249.18 EAQ93794.1 - 2.8e-37 126.7 0.1 3.2e-37 126.5 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e SKG6 PF08693.10 EAQ93796.1 - 2.3 7.7 9.1 5 6.6 9.1 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain adh_short_C2 PF13561.6 EAQ93797.1 - 1.2e-52 178.8 0.0 1.6e-52 178.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EAQ93797.1 - 1.1e-47 162.1 0.1 1.4e-47 161.7 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EAQ93797.1 - 5.2e-07 29.7 0.1 6.9e-07 29.3 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EAQ93797.1 - 0.0021 17.6 0.0 0.0027 17.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EAQ93797.1 - 0.015 14.8 0.0 0.021 14.2 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase DUF2974 PF11187.8 EAQ93797.1 - 0.067 12.7 0.0 0.17 11.4 0.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2974) DUF1776 PF08643.10 EAQ93797.1 - 0.2 11.0 0.0 0.32 10.3 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) PAF-AH_p_II PF03403.13 EAQ93798.1 - 9.9e-05 21.0 0.0 0.00011 20.8 0.0 1.1 1 0 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 EAQ93798.1 - 0.0014 17.6 0.0 0.0017 17.3 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_5 PF12695.7 EAQ93798.1 - 0.1 12.4 0.0 0.13 12.1 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase family Peripla_BP_6 PF13458.6 EAQ93798.1 - 0.2 11.3 0.0 0.29 10.8 0.0 1.1 1 0 0 1 1 1 0 Periplasmic binding protein Zn_clus PF00172.18 EAQ93799.1 - 7.1e-05 22.8 4.2 0.0002 21.4 4.2 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fructosamin_kin PF03881.14 EAQ93800.1 - 3.9e-11 42.7 0.0 1.1e-10 41.3 0.0 1.5 2 0 0 2 2 2 1 Fructosamine kinase CorA PF01544.18 EAQ93801.1 - 1.2e-15 57.6 0.2 2.2e-15 56.7 0.2 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Peptidase_S8 PF00082.22 EAQ93801.1 - 5.6e-11 42.3 0.2 9.8e-11 41.4 0.2 1.3 1 0 0 1 1 1 1 Subtilase family ACR_tran PF00873.19 EAQ93801.1 - 0.14 9.8 1.4 0.21 9.2 1.4 1.1 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family Acetyltransf_9 PF13527.7 EAQ93802.1 - 0.00013 22.1 0.0 0.0065 16.5 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EAQ93802.1 - 0.0059 16.8 0.0 0.69 10.2 0.0 2.6 2 1 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_15 PF17013.5 EAQ93802.1 - 0.065 12.7 0.0 0.095 12.2 0.0 1.2 1 0 0 1 1 1 0 Putative acetyl-transferase Acetyltransf_10 PF13673.7 EAQ93802.1 - 0.098 12.6 0.0 0.31 11.0 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EAQ93802.1 - 0.16 12.4 0.0 0.3 11.5 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DASH_Duo1 PF08651.10 EAQ93804.1 - 0.078 12.8 0.0 1.7 8.5 0.0 2.5 2 0 0 2 2 2 0 DASH complex subunit Duo1 Zn_clus PF00172.18 EAQ93805.1 - 0.041 14.0 4.5 0.072 13.2 4.5 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain RPEL PF02755.15 EAQ93806.1 - 0.14 11.9 0.1 0.23 11.2 0.1 1.4 1 0 0 1 1 1 0 RPEL repeat Dimer_Tnp_hAT PF05699.14 EAQ93808.1 - 3.1e-16 58.9 0.3 7.8e-16 57.7 0.3 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-BED PF02892.15 EAQ93808.1 - 0.085 12.9 0.1 0.22 11.6 0.1 1.7 1 0 0 1 1 1 0 BED zinc finger DJ-1_PfpI PF01965.24 EAQ93809.1 - 8.4e-11 41.9 0.0 1.1e-10 41.6 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family WD40 PF00400.32 EAQ93810.1 - 3.8e-05 24.3 21.4 0.00026 21.7 0.2 5.7 6 0 0 6 6 6 2 WD domain, G-beta repeat Zn_ribbon_17 PF17120.5 EAQ93810.1 - 0.011 15.3 2.1 0.011 15.3 2.1 2.9 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type ANAPC4_WD40 PF12894.7 EAQ93810.1 - 0.013 15.8 0.0 0.37 11.1 0.0 3.1 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain DUF4379 PF14311.6 EAQ93810.1 - 0.064 13.6 7.4 0.16 12.3 0.9 2.8 2 0 0 2 2 2 0 Probable Zinc-ribbon domain Ribosomal_L37ae PF01780.19 EAQ93810.1 - 0.33 11.1 4.1 1 9.5 4.1 1.8 1 0 0 1 1 1 0 Ribosomal L37ae protein family PHD PF00628.29 EAQ93810.1 - 0.42 10.5 5.9 7 6.6 0.3 3.1 2 0 0 2 2 2 0 PHD-finger zf-CHY PF05495.12 EAQ93810.1 - 0.63 10.6 6.4 0.15 12.5 2.8 1.8 2 0 0 2 2 2 0 CHY zinc finger zinc-ribbons_6 PF07191.12 EAQ93810.1 - 2.4 8.2 5.5 6.5 6.8 5.5 1.6 1 0 0 1 1 1 0 zinc-ribbons Cactin_mid PF10312.9 EAQ93811.1 - 8.7e-65 218.2 4.1 1.2e-64 217.8 4.1 1.2 1 0 0 1 1 1 1 Conserved mid region of cactin CactinC_cactus PF09732.9 EAQ93811.1 - 9.4e-57 190.4 5.4 1.5e-56 189.7 5.4 1.3 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein SF3A2 PF16835.5 EAQ93811.1 - 0.014 15.7 0.0 0.034 14.5 0.0 1.6 1 0 0 1 1 1 0 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) DUF1087 PF06465.13 EAQ93811.1 - 0.15 12.1 4.3 0.49 10.5 0.3 2.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1087) Forkhead PF00250.18 EAQ93813.1 - 2.3e-21 75.8 0.2 5.4e-21 74.7 0.2 1.5 1 0 0 1 1 1 1 Forkhead domain XLF PF09302.11 EAQ93814.1 - 1.6e-53 181.5 0.0 2.6e-53 180.8 0.0 1.3 1 0 0 1 1 1 1 XLF-Cernunnos, XRcc4-like factor, NHEJ component Phage_HK97_TLTM PF06120.11 EAQ93815.1 - 0.0008 18.7 0.5 0.0014 17.8 0.5 1.3 1 0 0 1 1 1 1 Tail length tape measure protein Yip1 PF04893.17 EAQ93815.1 - 0.047 13.4 0.0 0.082 12.6 0.0 1.3 1 0 0 1 1 1 0 Yip1 domain Gram_pos_anchor PF00746.21 EAQ93815.1 - 0.071 13.1 2.7 0.2 11.6 2.7 1.8 1 0 0 1 1 1 0 LPXTG cell wall anchor motif DUF4292 PF14125.6 EAQ93815.1 - 0.14 11.8 0.1 0.24 11.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4292) IHABP4_N PF16174.5 EAQ93816.1 - 0.71 10.5 9.2 0.95 10.0 9.2 1.3 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal Hamartin PF04388.12 EAQ93816.1 - 1.2 7.8 9.0 1.2 7.7 9.0 1.1 1 0 0 1 1 1 0 Hamartin protein Ank_2 PF12796.7 EAQ93817.1 - 1.4e-08 35.2 0.0 0.0018 18.8 0.0 3.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAQ93817.1 - 4.6e-07 29.6 0.4 5.2 8.0 0.0 4.8 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.6 EAQ93817.1 - 0.0001 22.8 0.5 0.34 11.5 0.0 3.7 3 1 0 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAQ93817.1 - 0.0014 18.9 0.1 1.8 9.0 0.0 3.7 4 1 0 4 4 4 1 Ankyrin repeats (many copies) ECM1 PF05782.11 EAQ93819.1 - 0.025 13.5 0.7 0.03 13.3 0.7 1.0 1 0 0 1 1 1 0 Extracellular matrix protein 1 (ECM1) RVT_1 PF00078.27 EAQ93820.1 - 7.1e-36 123.8 0.0 4e-35 121.3 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 EAQ93820.1 - 0.0023 17.9 1.7 0.0023 17.9 1.7 2.6 2 0 0 2 2 1 1 Zinc knuckle SlyX PF04102.12 EAQ93820.1 - 0.0049 17.5 5.6 0.071 13.7 5.6 2.9 1 1 0 1 1 1 1 SlyX USP8_interact PF08941.10 EAQ93820.1 - 0.058 13.2 0.1 0.17 11.7 0.1 1.9 1 0 0 1 1 1 0 USP8 interacting CorA PF01544.18 EAQ93820.1 - 0.062 12.6 1.5 0.15 11.4 1.5 1.5 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein CENP-F_leu_zip PF10473.9 EAQ93820.1 - 0.072 13.1 0.8 0.21 11.6 0.8 1.8 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HMMR_N PF15905.5 EAQ93820.1 - 0.077 12.5 0.4 0.13 11.7 0.4 1.2 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal PKcGMP_CC PF16808.5 EAQ93820.1 - 0.11 12.3 0.6 0.36 10.7 0.6 1.9 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF3584 PF12128.8 EAQ93820.1 - 0.26 8.7 4.6 0.43 8.0 4.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) UPF0242 PF06785.11 EAQ93820.1 - 0.29 11.2 1.3 0.6 10.2 1.3 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus YlqD PF11068.8 EAQ93820.1 - 0.72 10.2 3.6 2.5 8.5 3.6 1.8 1 0 0 1 1 1 0 YlqD protein FAM76 PF16046.5 EAQ93820.1 - 2.2 7.6 11.9 2.1 7.6 0.8 2.6 2 0 0 2 2 2 0 FAM76 protein Exonuc_VII_L PF02601.15 EAQ93820.1 - 3.4 7.2 7.8 1.5 8.3 4.5 2.0 2 0 0 2 2 2 0 Exonuclease VII, large subunit KELK PF15796.5 EAQ93820.1 - 9.2 6.8 7.9 14 6.2 3.3 2.7 2 0 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Atg14 PF10186.9 EAQ93822.1 - 5.7e-20 71.7 3.7 4.5e-19 68.7 3.7 2.0 1 1 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 VPS38 PF17649.1 EAQ93822.1 - 4.5e-10 39.0 1.1 2.1e-06 26.9 0.0 3.2 4 0 0 4 4 4 2 Vacuolar protein sorting 38 ABC_tran_Xtn PF12848.7 EAQ93822.1 - 0.64 10.1 7.3 1.2 9.2 7.3 1.4 1 0 0 1 1 1 0 ABC transporter SKG6 PF08693.10 EAQ93823.1 - 9.8e-06 24.9 1.0 2.7e-05 23.5 1.0 1.8 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4448 PF14610.6 EAQ93823.1 - 0.00052 19.8 0.0 0.00082 19.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) DUF1180 PF06679.12 EAQ93823.1 - 0.0013 19.1 0.4 0.0027 18.1 0.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1180) Rax2 PF12768.7 EAQ93823.1 - 0.029 13.8 0.0 0.041 13.3 0.0 1.3 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Adeno_E3_CR2 PF02439.15 EAQ93823.1 - 0.1 12.4 0.1 0.18 11.6 0.1 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 EphA2_TM PF14575.6 EAQ93823.1 - 0.15 13.0 0.0 0.35 11.8 0.0 1.6 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 EAQ93823.1 - 1.1 9.1 7.2 29 4.5 5.8 2.5 3 0 0 3 3 3 0 TMEM154 protein family Granulin PF00396.18 EAQ93823.1 - 4.2 7.8 7.8 3.5 8.0 3.2 2.4 2 0 0 2 2 2 0 Granulin MULE PF10551.9 EAQ93826.1 - 6.4e-22 77.8 0.1 1.2e-21 76.9 0.1 1.5 1 0 0 1 1 1 1 MULE transposase domain FAR1 PF03101.15 EAQ93826.1 - 7.2e-05 23.4 0.5 0.00017 22.2 0.5 1.6 1 0 0 1 1 1 1 FAR1 DNA-binding domain Transposase_mut PF00872.18 EAQ93826.1 - 0.0067 15.3 0.0 0.011 14.6 0.0 1.2 1 0 0 1 1 1 1 Transposase, Mutator family AT_hook PF02178.19 EAQ93826.1 - 2.6 8.2 26.2 0.2 11.6 5.2 4.1 3 0 0 3 3 3 0 AT hook motif Sporozoite_P67 PF05642.11 EAQ93828.1 - 0.024 12.7 5.5 0.029 12.5 5.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Maff2 PF12750.7 EAQ93828.1 - 0.16 11.9 1.5 0.31 10.9 0.8 1.8 2 0 0 2 2 2 0 Maff2 family CCDC158 PF15921.5 EAQ93828.1 - 1.3 6.8 3.5 1.6 6.5 3.5 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 158 MFS_1 PF07690.16 EAQ93829.1 - 4.1e-41 141.1 56.2 4.1e-41 141.1 56.2 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily Polyketide_cyc2 PF10604.9 EAQ93830.1 - 9.3e-12 45.4 0.0 1.1e-11 45.2 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 EAQ93830.1 - 0.11 12.8 0.0 0.16 12.2 0.0 1.5 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport DUF3102 PF11300.8 EAQ93830.1 - 0.11 12.7 0.0 0.16 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3102) Glyco_hydro_11 PF00457.17 EAQ93832.1 - 1.5e-63 213.7 19.6 1.4e-61 207.2 19.6 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 11 ADH_zinc_N PF00107.26 EAQ93833.1 - 3.2e-21 75.7 0.7 6e-21 74.8 0.7 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EAQ93833.1 - 5.4e-21 74.5 0.9 1.2e-20 73.4 0.2 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 EAQ93833.1 - 2.8e-06 27.0 0.2 4.1e-06 26.4 0.2 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus AMP-binding PF00501.28 EAQ93833.1 - 0.0029 16.3 0.5 0.0048 15.5 0.5 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AlaDh_PNT_C PF01262.21 EAQ93833.1 - 0.02 14.2 4.8 0.042 13.1 4.8 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.6 EAQ93833.1 - 0.075 14.1 0.1 0.19 12.8 0.1 1.8 1 1 0 1 1 1 0 Zinc-binding dehydrogenase GCD14 PF08704.10 EAQ93833.1 - 0.1 12.3 0.3 0.21 11.3 0.0 1.6 2 0 0 2 2 2 0 tRNA methyltransferase complex GCD14 subunit Titin_Z PF09042.11 EAQ93833.1 - 0.26 11.3 0.9 0.55 10.2 0.9 1.5 1 0 0 1 1 1 0 Titin Z p450 PF00067.22 EAQ93834.1 - 4.6e-65 220.2 0.0 5.8e-65 219.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.18 EAQ93835.1 - 4.9e-10 38.9 0.1 3.8e-08 32.7 0.0 2.3 2 0 0 2 2 2 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.6 EAQ93835.1 - 7.4e-07 29.3 6.8 0.00017 21.8 2.0 2.9 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 EAQ93835.1 - 2.7e-06 27.5 12.9 0.00051 20.4 7.0 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 EAQ93835.1 - 3.3e-06 27.2 1.3 0.032 14.5 0.6 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding Zn_clus PF00172.18 EAQ93835.1 - 2.2e-05 24.5 10.1 5.2e-05 23.3 10.1 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_4 PF13894.6 EAQ93835.1 - 4.7e-05 23.9 13.7 0.016 16.0 5.1 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 EAQ93835.1 - 0.0031 17.5 10.1 0.26 11.3 2.9 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 EAQ93835.1 - 0.014 15.7 4.6 1.3 9.5 1.0 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2HE PF16278.5 EAQ93835.1 - 0.18 12.3 3.0 0.56 10.7 3.0 1.8 1 0 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger zf-Di19 PF05605.12 EAQ93835.1 - 0.4 11.0 5.1 1.2 9.5 5.1 1.8 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.7 EAQ93835.1 - 4.3 7.7 7.8 9.9 6.6 0.2 2.6 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) F-box-like PF12937.7 EAQ93836.1 - 0.0022 17.8 2.4 0.0096 15.8 2.4 2.1 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 EAQ93837.1 - 0.76 9.7 3.5 13 5.8 0.0 3.9 4 0 0 4 4 4 0 F-box domain zf-RVT PF13966.6 EAQ93838.1 - 0.039 14.7 0.1 0.17 12.6 0.0 2.1 2 0 0 2 2 2 0 zinc-binding in reverse transcriptase Glyco_hydro_11 PF00457.17 EAQ93839.1 - 5e-80 267.3 15.3 5.8e-80 267.1 15.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 FA_desaturase PF00487.24 EAQ93841.1 - 2.2 8.1 8.6 0.11 12.3 1.5 2.2 2 0 0 2 2 2 0 Fatty acid desaturase GRDP-like PF07173.12 EAQ93846.1 - 5.7e-18 65.9 1.4 8.6e-13 49.1 0.0 2.8 2 1 0 2 2 2 2 Glycine-rich domain-containing protein-like Mu-like_Com PF10122.9 EAQ93846.1 - 0.088 12.3 0.1 0.7 9.4 0.1 2.2 2 0 0 2 2 2 0 Mu-like prophage protein Com Glyco_hydro_75 PF07335.11 EAQ93849.1 - 3.5e-57 193.2 0.0 6.4e-57 192.4 0.0 1.4 1 0 0 1 1 1 1 Fungal chitosanase of glycosyl hydrolase group 75 APH PF01636.23 EAQ93850.1 - 2.2e-09 37.6 0.8 3.7e-09 36.9 0.1 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EAQ93850.1 - 7.5e-07 28.9 0.1 1e-06 28.5 0.1 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.20 EAQ93850.1 - 0.079 12.3 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Pkinase PF00069.25 EAQ93850.1 - 0.094 12.1 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain Malic_M PF03949.15 EAQ93852.1 - 4.2e-88 294.9 0.1 5.6e-88 294.5 0.1 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 EAQ93852.1 - 5.9e-39 133.7 0.0 4e-26 91.9 0.0 2.3 2 0 0 2 2 2 2 Malic enzyme, N-terminal domain Ribosomal_L14 PF00238.19 EAQ93853.1 - 8.5e-33 113.0 0.0 1e-32 112.8 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e HET PF06985.11 EAQ93854.1 - 8.5e-13 48.9 3.9 4.5e-07 30.3 0.2 3.4 2 1 1 3 3 3 3 Heterokaryon incompatibility protein (HET) TraK PF06586.11 EAQ93854.1 - 0.12 12.0 1.1 0.21 11.3 1.1 1.3 1 0 0 1 1 1 0 TraK protein DUF4683 PF15735.5 EAQ93855.1 - 0.077 12.6 1.3 0.23 11.0 1.3 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4683) DUF5427 PF10310.9 EAQ93856.1 - 1.2e-180 601.4 0.0 1.4e-180 601.2 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5427) Flu_M1_C PF08289.11 EAQ93856.1 - 0.1 12.8 1.6 0.16 12.2 0.2 2.0 2 0 0 2 2 2 0 Influenza Matrix protein (M1) C-terminal domain SARAF PF06682.12 EAQ93856.1 - 0.14 11.8 3.6 0.25 11.0 3.6 1.3 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Pol_alpha_B_N PF08418.10 EAQ93856.1 - 0.29 11.1 4.7 0.49 10.3 4.7 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal CDH-cyt PF16010.5 EAQ93857.1 - 2.7e-46 157.6 3.4 3.1e-46 157.4 3.4 1.0 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase DOMON PF03351.17 EAQ93857.1 - 0.00055 20.2 0.0 0.00095 19.4 0.0 1.3 1 0 0 1 1 1 1 DOMON domain Zip PF02535.22 EAQ93858.1 - 2e-57 194.9 0.2 2.4e-57 194.7 0.2 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter DUF4381 PF14316.6 EAQ93860.1 - 0.041 14.1 4.6 0.21 11.8 0.0 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4381) 7TM-7TMR_HD PF07698.11 EAQ93860.1 - 0.55 10.0 6.6 0.23 11.2 1.3 2.2 2 0 0 2 2 2 0 7TM receptor with intracellular HD hydrolase Peptidase_C14 PF00656.22 EAQ93861.1 - 3.1e-28 99.4 0.0 5.2e-13 49.5 0.1 2.2 2 0 0 2 2 2 2 Caspase domain WW PF00397.26 EAQ93862.1 - 8.7e-07 28.9 7.9 8.7e-07 28.9 7.9 2.4 2 0 0 2 2 2 1 WW domain KinB_sensor PF16767.5 EAQ93862.1 - 0.006 17.0 1.9 0.0099 16.3 1.9 1.2 1 0 0 1 1 1 1 Sensor domain of alginate biosynthesis sensor protein KinB DUF4404 PF14357.6 EAQ93862.1 - 0.039 14.6 3.1 0.065 13.9 3.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) Romo1 PF10247.9 EAQ93862.1 - 0.044 14.1 0.4 0.071 13.5 0.4 1.2 1 0 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 LSM PF01423.22 EAQ93863.1 - 1.7e-21 75.7 0.7 1.9e-21 75.5 0.7 1.0 1 0 0 1 1 1 1 LSM domain Fe-ADH_2 PF13685.6 EAQ93864.1 - 0.13 11.9 0.1 0.21 11.3 0.1 1.2 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase OmpH PF03938.14 EAQ93864.1 - 4.4 7.7 9.4 16 5.8 9.4 1.9 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF3844 PF12955.7 EAQ93865.1 - 3.8e-36 123.4 2.8 6.3e-36 122.7 2.8 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) MFS_1 PF07690.16 EAQ93867.1 - 2.8e-33 115.3 29.3 4.1e-32 111.5 14.1 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EAQ93867.1 - 0.003 16.1 4.3 0.0047 15.4 4.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 EAQ93867.1 - 0.076 11.3 0.6 0.17 10.2 0.6 1.5 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Glyco_tranf_2_3 PF13641.6 EAQ93868.1 - 4.1e-25 89.0 0.0 5.2e-25 88.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 EAQ93868.1 - 5.8e-09 35.7 0.0 2.4e-08 33.6 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 EAQ93868.1 - 7.7e-07 29.1 0.0 1.1e-06 28.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.6 EAQ93868.1 - 4.4e-05 23.5 1.7 4.4e-05 23.5 1.7 2.0 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Beta-lactamase PF00144.24 EAQ93869.1 - 2.2e-28 99.5 3.4 9.3e-20 71.1 0.1 2.5 3 0 0 3 3 3 2 Beta-lactamase BNR_4 PF15892.5 EAQ93871.1 - 1.5e-40 139.3 0.0 2e-40 138.9 0.0 1.1 1 0 0 1 1 1 1 BNR repeat-containing family member Sugar_tr PF00083.24 EAQ93872.1 - 6.7e-118 394.4 21.6 7.8e-118 394.2 21.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EAQ93872.1 - 9.6e-24 83.9 48.4 7.1e-21 74.5 18.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EAQ93872.1 - 0.0012 17.4 3.8 0.0012 17.4 3.8 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) OPT PF03169.15 EAQ93873.1 - 1.3e-79 268.4 46.0 1.6e-79 268.2 46.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein FhuF_C PF11575.8 EAQ93874.1 - 0.14 12.1 0.8 0.14 12.1 0.8 2.4 2 0 0 2 2 2 0 FhuF 2Fe-2S C-terminal domain Asp PF00026.23 EAQ93875.1 - 1.2e-75 254.9 4.8 1.4e-75 254.7 4.8 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EAQ93875.1 - 6.1e-15 55.9 2.2 1.7e-07 31.6 0.1 3.1 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EAQ93875.1 - 0.0001 22.9 1.3 0.17 12.6 0.4 3.3 2 1 0 2 2 2 2 Aspartyl protease PIF1 PF05970.14 EAQ93876.1 - 7.1e-06 25.4 0.2 1.2e-05 24.7 0.2 1.3 1 0 0 1 1 1 1 PIF1-like helicase UvrD_C_2 PF13538.6 EAQ93876.1 - 0.0096 15.7 0.0 0.031 14.1 0.0 1.9 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain PEGSRP PF07623.11 EAQ93876.1 - 0.14 12.0 0.9 6.7 6.6 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1584) Tim17 PF02466.19 EAQ93878.1 - 0.039 14.3 7.5 0.19 12.1 7.4 1.9 1 1 1 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family Pro_dh PF01619.18 EAQ93879.1 - 4e-72 243.3 0.0 4.7e-72 243.0 0.0 1.0 1 0 0 1 1 1 1 Proline dehydrogenase HTH_5 PF01022.20 EAQ93879.1 - 0.1 12.5 0.1 0.38 10.6 0.0 2.0 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family Fungal_trans PF04082.18 EAQ93880.1 - 4.4e-11 42.3 0.0 7.1e-11 41.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EAQ93880.1 - 2.2e-08 34.1 7.2 4.9e-08 33.0 7.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 EAQ93881.1 - 1.5e-23 83.3 22.9 2.5e-23 82.6 22.9 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily NIF PF03031.18 EAQ93884.1 - 7.5e-38 129.7 0.1 1.1e-37 129.2 0.1 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF737 PF05300.11 EAQ93884.1 - 3.2 8.0 14.4 11 6.4 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF737) NMO PF03060.15 EAQ93886.1 - 1.4e-28 100.3 9.4 6.6e-24 84.9 3.3 2.2 2 0 0 2 2 2 2 Nitronate monooxygenase IMPDH PF00478.25 EAQ93886.1 - 8.4e-08 31.6 2.1 1.4e-06 27.6 2.1 2.0 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 EAQ93886.1 - 6.7e-06 25.4 4.8 1.2e-05 24.5 4.8 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase OpuAC PF04069.12 EAQ93886.1 - 0.056 13.0 0.0 1.6 8.2 0.0 2.1 2 0 0 2 2 2 0 Substrate binding domain of ABC-type glycine betaine transport system SnoaL PF07366.12 EAQ93887.1 - 2e-13 50.2 0.0 1.3e-12 47.6 0.0 2.1 2 0 0 2 2 2 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 EAQ93887.1 - 8.3e-05 23.2 0.0 0.00017 22.2 0.0 1.5 1 0 0 1 1 1 1 SnoaL-like domain DUF3302 PF11742.8 EAQ93887.1 - 0.075 13.2 1.2 0.21 11.8 1.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3302) RhoGAP PF00620.27 EAQ93888.1 - 1.1e-15 57.7 0.0 2.7e-15 56.5 0.0 1.7 1 0 0 1 1 1 1 RhoGAP domain Helo_like_N PF17111.5 EAQ93888.1 - 0.034 13.5 0.0 0.051 12.9 0.0 1.3 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins Methyltransf_31 PF13847.6 EAQ93889.1 - 4e-06 26.7 0.0 5.2e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAQ93889.1 - 3.2e-05 24.6 0.0 5.4e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EAQ93889.1 - 0.00067 20.3 0.0 0.0012 19.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EAQ93889.1 - 0.018 15.8 0.1 0.026 15.2 0.1 1.2 1 0 0 1 1 1 0 Methyltransferase domain PTS_2-RNA PF01885.16 EAQ93890.1 - 4.7e-24 85.4 0.0 7.2e-24 84.8 0.0 1.2 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family La PF05383.17 EAQ93890.1 - 0.17 12.0 0.0 0.36 10.9 0.0 1.5 1 0 0 1 1 1 0 La domain AP_endonuc_2 PF01261.24 EAQ93891.1 - 3.8e-41 140.9 0.0 4.5e-41 140.6 0.0 1.1 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel LPD22 PF18834.1 EAQ93891.1 - 0.14 12.4 0.0 0.6 10.3 0.0 2.0 2 1 0 2 2 2 0 Large polyvalent protein associated domain 22 FBPase PF00316.20 EAQ93892.1 - 0.17 11.3 0.0 0.3 10.5 0.0 1.4 1 0 0 1 1 1 0 Fructose-1-6-bisphosphatase, N-terminal domain MFS_1 PF07690.16 EAQ93893.1 - 1e-45 156.2 53.9 4.8e-44 150.7 53.9 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EAQ93893.1 - 2e-17 63.2 35.2 1.4e-15 57.1 13.2 2.8 2 1 1 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 EAQ93893.1 - 3.6e-14 52.1 16.8 3.6e-14 52.1 16.8 1.4 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 EAQ93893.1 - 0.0072 14.7 15.9 0.064 11.5 2.1 2.8 2 1 1 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family DUF3318 PF11780.8 EAQ93893.1 - 0.73 9.8 4.1 0.17 11.8 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3318) Pox_A14 PF05767.12 EAQ93893.1 - 1.2 9.3 5.8 0.89 9.8 0.5 2.8 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 zf-CCHC PF00098.23 EAQ93894.1 - 2e-05 24.4 3.4 3.4e-05 23.7 3.4 1.4 1 0 0 1 1 1 1 Zinc knuckle PspA_IM30 PF04012.12 EAQ93894.1 - 0.00085 19.0 4.7 0.0014 18.3 4.7 1.3 1 0 0 1 1 1 1 PspA/IM30 family COG2 PF06148.11 EAQ93894.1 - 0.0011 19.0 3.6 0.0022 18.1 3.6 1.5 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF812 PF05667.11 EAQ93894.1 - 0.0024 16.8 3.1 0.0032 16.4 3.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Spc7 PF08317.11 EAQ93894.1 - 0.0062 15.5 4.0 0.0088 15.0 4.0 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF148 PF02520.17 EAQ93894.1 - 0.0069 16.5 6.2 0.014 15.5 6.2 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF148 Golgin_A5 PF09787.9 EAQ93894.1 - 0.012 15.1 5.8 0.019 14.4 5.8 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 Filament PF00038.21 EAQ93894.1 - 0.028 14.0 4.9 0.05 13.2 4.9 1.3 1 0 0 1 1 1 0 Intermediate filament protein TPR_MLP1_2 PF07926.12 EAQ93894.1 - 0.046 13.8 8.4 0.23 11.5 8.4 2.1 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF2408 PF10303.9 EAQ93894.1 - 0.063 13.8 3.5 0.6 10.7 3.5 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) HIP1_clath_bdg PF16515.5 EAQ93894.1 - 0.072 13.7 6.5 0.15 12.7 6.5 1.6 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 TMPIT PF07851.13 EAQ93894.1 - 0.14 11.4 1.5 0.19 10.9 1.5 1.1 1 0 0 1 1 1 0 TMPIT-like protein H-kinase_dim PF02895.14 EAQ93894.1 - 0.15 12.5 2.8 0.18 12.2 1.6 1.7 1 1 0 1 1 1 0 Signal transducing histidine kinase, homodimeric domain DUF1664 PF07889.12 EAQ93894.1 - 0.15 12.1 5.1 0.34 10.9 4.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) USP8_interact PF08941.10 EAQ93894.1 - 0.15 11.9 2.0 0.24 11.2 2.0 1.3 1 0 0 1 1 1 0 USP8 interacting CENP-F_leu_zip PF10473.9 EAQ93894.1 - 0.17 11.9 8.4 0.71 9.9 8.3 1.9 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SlyX PF04102.12 EAQ93894.1 - 0.23 12.1 4.8 0.56 10.9 4.5 1.8 1 1 0 1 1 1 0 SlyX Baculo_PEP_C PF04513.12 EAQ93894.1 - 0.27 11.3 10.7 0.4 10.7 10.7 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus TolA_bind_tri PF16331.5 EAQ93894.1 - 0.38 10.9 3.9 0.75 9.9 3.8 1.6 1 1 0 1 1 1 0 TolA binding protein trimerisation FlaC_arch PF05377.11 EAQ93894.1 - 0.75 10.2 5.0 0.43 11.0 1.8 2.3 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) MIS13 PF08202.11 EAQ93894.1 - 0.78 9.0 6.3 1.5 8.0 6.2 1.5 1 1 1 2 2 2 0 Mis12-Mtw1 protein family YabA PF06156.13 EAQ93894.1 - 2.5 8.8 6.2 3.1 8.5 4.6 2.0 2 0 0 2 2 2 0 Initiation control protein YabA FAM76 PF16046.5 EAQ93894.1 - 4.7 6.5 12.2 0.24 10.7 2.6 2.1 2 0 0 2 2 2 0 FAM76 protein DDE_1 PF03184.19 EAQ93895.1 - 1.3e-26 93.3 0.0 2.3e-26 92.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.16 EAQ93895.1 - 7.6e-09 35.2 0.0 1.8e-08 34.0 0.0 1.7 1 0 0 1 1 1 1 helix-turn-helix, Psq domain SpoIIID PF12116.8 EAQ93895.1 - 0.051 13.7 0.0 0.3 11.2 0.0 2.1 2 0 0 2 2 2 0 Stage III sporulation protein D adh_short_C2 PF13561.6 EAQ93896.1 - 3.3e-57 193.7 0.9 3.8e-57 193.5 0.9 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EAQ93896.1 - 1.9e-45 154.7 0.7 2.2e-45 154.5 0.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EAQ93896.1 - 6.1e-14 52.3 0.5 7.7e-14 52.0 0.5 1.2 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 EAQ93896.1 - 0.00099 18.5 0.2 0.0023 17.3 0.1 1.7 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.21 EAQ93896.1 - 0.001 18.6 0.3 0.0031 17.0 0.3 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family AdoHcyase_NAD PF00670.21 EAQ93896.1 - 0.0073 16.4 0.5 0.012 15.7 0.5 1.4 1 1 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Eno-Rase_NADH_b PF12242.8 EAQ93896.1 - 0.18 11.6 1.0 0.41 10.4 1.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Sugar_tr PF00083.24 EAQ93897.1 - 4.6e-82 276.3 20.3 5.2e-82 276.1 20.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EAQ93897.1 - 9.2e-22 77.4 48.7 1.1e-16 60.8 15.3 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 EAQ93897.1 - 3.3e-05 23.4 9.3 3.3e-05 23.4 9.3 2.3 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB MFS_1_like PF12832.7 EAQ93897.1 - 3.9 6.2 16.1 0.62 8.9 4.6 2.4 2 1 0 2 2 2 0 MFS_1 like family Lig_chan PF00060.26 EAQ93897.1 - 4 7.3 6.7 0.51 10.2 0.8 2.4 2 1 0 2 2 2 0 Ligand-gated ion channel Fungal_trans_2 PF11951.8 EAQ93898.1 - 1.6e-05 24.0 0.2 2.6e-05 23.2 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EAQ93898.1 - 0.092 12.9 1.6 0.25 11.5 1.6 1.7 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF89 PF01937.19 EAQ93899.1 - 3.2e-94 315.8 0.0 4e-94 315.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function DUF89 AnmK PF03702.14 EAQ93900.1 - 2.5e-68 230.8 0.0 4.7e-68 230.0 0.0 1.4 1 0 0 1 1 1 1 Anhydro-N-acetylmuramic acid kinase OrsD PF12013.8 EAQ93900.1 - 3.4e-22 79.0 6.7 1.4e-10 41.6 0.1 2.8 2 0 0 2 2 2 2 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2H2_2 PF12756.7 EAQ93900.1 - 0.28 11.5 2.0 32 4.9 0.1 3.0 4 0 0 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-BED PF02892.15 EAQ93900.1 - 2 8.5 4.8 12 6.0 1.2 3.1 3 0 0 3 3 3 0 BED zinc finger # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Chaetomium_globosum_CBS_148.51-ASM14336v1/GCA_000143365.1_ASM14336v1_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Chaetomium_globosum_CBS_148.51-ASM14336v1/GCA_000143365.1_ASM14336v1_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Chaetomium_globosum_CBS_148.51-ASM14336v1/GCA_000143365.1_ASM14336v1_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Chaetomium_globosum_CBS_148.51-ASM14336v1/GCA_000143365.1_ASM14336v1_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Sun Mar 24 16:48:06 2019 # [ok]